                              Sequence Listing

<110> Genentech Inc.

<120> Compositions and methods for the treatment of immune
      related diseases

<130> P2053R1

<141> 2004-08-10

<150> US 60/493,546
<151> 2003-08-11

<160> 6464

<210> 1
<211> 562
<212> DNA
<213> Homo sapien

<400> 1
 gccggaaccg ccatcttcca gtaattcgcc aaaatgacga acacaaaggg 50

 aaagaggaga ggcacccgat atatgttctc taggcctttt agaaaacatg 100

 gagttgttcc tttggccaca tatatgcgaa tctataagaa aggtgatatt 150

 gtagacatca agggaatggg tactgttcaa aaaggaatgc cccacaagtg 200

 ttaccatggc aaaactggaa gagtctacaa tgttacccag catgctgctg 250

 gcattgttgt aaacgaacaa gttaagggca agattcttgc caagagaatt 300

 aatgtgcgta ttgagcacat taagcactct aagagccgag ataacttcct 350

 gaaacgtgtg aaggragatg atcaggaaaa graagaagcc caagagaaag 400

 gtacctgggt tcaactaaag cgccamcctg ctccacccag agaagcacac 450

 tttgtgagaa ccaatgggaa ggagcctgag ctgctggaac ctattcccta 500

 tgaattcatg gcataatagg tgttaaaaaa aaaataaagg acctctgggc 550

 taccaaaaaa aa 562

<210> 2
<211> 160
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 111, 117, 131
<223> unknown amino acid

<400> 2
 Met Thr Asn Thr Lys Gly Lys Arg Arg Gly Thr Arg Tyr Met Phe
   1               5                  10                  15

 Ser Arg Pro Phe Arg Lys His Gly Val Val Pro Leu Ala Thr Tyr
                  20                  25                  30

 Met Arg Ile Tyr Lys Lys Gly Asp Ile Val Asp Ile Lys Gly Met
                  35                  40                  45

 Gly Thr Val Gln Lys Gly Met Pro His Lys Cys Tyr His Gly Lys
                  50                  55                  60

 Thr Gly Arg Val Tyr Asn Val Thr Gln His Ala Ala Gly Ile Val
                  65                  70                  75

 Val Asn Glu Gln Val Lys Gly Lys Ile Leu Ala Lys Arg Ile Asn
                  80                  85                  90

 Val Arg Ile Glu His Ile Lys His Ser Lys Ser Arg Asp Asn Phe
                  95                 100                 105

 Leu Lys Arg Val Lys Xaa Asp Asp Gln Glu Lys Xaa Glu Ala Gln
                 110                 115                 120

 Glu Lys Gly Thr Trp Val Gln Leu Lys Arg Xaa Pro Ala Pro Pro
                 125                 130                 135

 Arg Glu Ala His Phe Val Arg Thr Asn Gly Lys Glu Pro Glu Leu
                 140                 145                 150

 Leu Glu Pro Ile Pro Tyr Glu Phe Met Ala
                 155                 160

<210> 3
<211> 2714
<212> DNA
<213> Homo sapien

<400> 3
 ccgacatgtt gagtcataag acgcgtcggt gttgcagtct gtgtccttgg 50

 aggtgaccag ggccactgca ggcatggtgc tagcagagct gtacgtctct 100

 gaccgagagg gaagcgatgc cacgggagat ggaaccaagg agaaaccatt 150

 taaaacaggt ctaaaggctt tgatgacagt agggaaagaa ccatttccta 200

 ccatttacgt agattcacaa aaagaaaatg agaggtggaa tgttatttct 250

 aaatcacagt tgaagaacat taaaaagatg tggcataggg aacaaatgaa 300

 gagtgaatcc cgggaaaaga aagaggcaga agatagttta cgaagagaaa 350

 agaacctgga agaagcaaag aagattacca ttaaaaatga tccaagtctc 400

 ccagagccaa aatgtgtgaa gattggtgcg ttagaaggat atagaggcca 450

 aagagtaaag gtgtttggct gggtccacag gctgcgcagg caaggaaaga 500

 atttaatgtt tctggtgttg cgagatggta caggttatct tcagtgtgtc 550

 ttggcggatg agttgtgtca gtgctacaat ggagttctct tgtccacgga 600

 gagcagtgtt gcagtgtatg gaatgctaaa tcttacccca aagggcaagc 650

 aggctccagg tggccatgag ctgagttgtg acttctggga actaattggg 700

 ttggcccctg ctggaggagc tgacaacctg atcaatgagg agtctgacgt 750

 tgatgtccag ctcaacaaca gacacatgat gatccgagga gaaaacatgt 800

 ccaaaatcct aaaagcacga tccatggtca ccaggtgctt tagagatcac 850

 ttctttgata gggggtacta tgaagttact cctccaacat tagtgcaaac 900

 acaagtagaa ggtggtgcca cactcttcaa gcttgactat tttggggaag 950

 aggcattttt gactcaatcc tctcagttgt acttggagac ctgcctccca 1000

 gccctgggag atgttttttg tattgctcag tcataccggg cagagcagtc 1050

 cagaacacga aggcacctgg ctgagtacac tcacgtggaa gctgagtgtc 1100

 ctttcctgac ttttgacgac ctcctgaacc ggttggagga cttggtttgt 1150

 gatgtggtag atcgaatatt gaagtcacct gcagggagca tagtgcatga 1200

 gctcaacccg aactttcagc cccccaaacg gcctttcaaa cggatgaact 1250

 attcagatgc tatcgtttgg ctaaaagaac atgatgtaaa gaaagaagat 1300

 ggaactttct atgaatttgg agaagatatc ccagaagctc ctgagagact 1350

 gatgacagac accattaatg aaccaatctt gctgtgtcga tttcctgtgg 1400

 agatcaagtc cttctacatg cagcgatgtc ctgaggattc ccgtcttact 1450

 gaatctgtcg acgtgttgat gcccaatgtt ggtgagattg tgggaggctc 1500

 aatgcgtatc tttgatagtg aagaaatact ggcaggttat aaaagggaag 1550

 ggattgaccc cactccctat tactggtata cggatcagag aaaatacggt 1600

 acatgtcccc atggaggata tggcttgggc ttggaacgat tcttaacgtg 1650

 gattctgaat aggtatcaca tccgagacgt gtgcttatac cctcgatttg 1700

 tccagcgttg cacgccataa ccattttctc cagaagcgtg gaggaaagat 1750

 tatgaaagga acaggctctt taaaaaagaa aacaaaaagc cagaatcttc 1800

 cttttttttg tttcattggg gtttctcttt ctgtttttct ttctactacc 1850

 ataaaaacta tctcaaatca cctgaacatc aagtgatatt aaggttgtca 1900

 tcttaagaaa aaatatccat ttttttctta agttcgggaa acaaagttcg 1950

 gggaaaatac ctggcatgaa actgtagtta gggatacatt tcagcatttt 2000

 actcacttta tccaagttat tcattttatt caagttatat gtatgtataa 2050

 ttcaacaatt ttagattatg gtgtaagata ctccagtaac ttatctttct 2100

 gtccttttaa gtgtacctgg aattctttga tttattttat tgcatcaatg 2150

 aattaaaaca aaaatcttgg gggaagaaat tggcaatatc gtataaaaat 2200

 ctgctcatat tagaacacag tataattcag cagtaaacac tagaatcaaa 2250

 tgaatagcct tttgtatcag ttattaatct tttctaactc tgcttagctg 2300

 ctaataatcc tgaggcatag aaattgaaga atttgtaaaa atagaattgc 2350

 cttaaaggat ttgaagtaag aacataattt tggggagagt tttttagtga 2400

 ttcacagtat ccctcttagc attaatttaa ggtaaagagg cagattgatt 2450

 ttccctcttt cctggtaatt cctaagtaat taagaataaa taagttccaa 2500

 aagaaattgt agctggaatc ttaataacaa ttgtgagtgg ctgtttgagt 2550

 tgcccccacc atgtccttag atctaatctg tgctacctta ttaactcaca 2600

 gcaggcttac tgaatggctt catttcagat ttagttgatt tctccaccaa 2650

 atgcatgtca tgtattctca ataggctgta ttcccagcag tcaataaatg 2700

 aacacccgta aaaa 2714

<210> 4
<211> 548
<212> PRT
<213> Homo sapien

<400> 4
 Met Val Leu Ala Glu Leu Tyr Val Ser Asp Arg Glu Gly Ser Asp
   1               5                  10                  15

 Ala Thr Gly Asp Gly Thr Lys Glu Lys Pro Phe Lys Thr Gly Leu
                  20                  25                  30

 Lys Ala Leu Met Thr Val Gly Lys Glu Pro Phe Pro Thr Ile Tyr
                  35                  40                  45

 Val Asp Ser Gln Lys Glu Asn Glu Arg Trp Asn Val Ile Ser Lys
                  50                  55                  60

 Ser Gln Leu Lys Asn Ile Lys Lys Met Trp His Arg Glu Gln Met
                  65                  70                  75

 Lys Ser Glu Ser Arg Glu Lys Lys Glu Ala Glu Asp Ser Leu Arg
                  80                  85                  90

 Arg Glu Lys Asn Leu Glu Glu Ala Lys Lys Ile Thr Ile Lys Asn
                  95                 100                 105

 Asp Pro Ser Leu Pro Glu Pro Lys Cys Val Lys Ile Gly Ala Leu
                 110                 115                 120

 Glu Gly Tyr Arg Gly Gln Arg Val Lys Val Phe Gly Trp Val His
                 125                 130                 135

 Arg Leu Arg Arg Gln Gly Lys Asn Leu Met Phe Leu Val Leu Arg
                 140                 145                 150

 Asp Gly Thr Gly Tyr Leu Gln Cys Val Leu Ala Asp Glu Leu Cys
                 155                 160                 165

 Gln Cys Tyr Asn Gly Val Leu Leu Ser Thr Glu Ser Ser Val Ala
                 170                 175                 180

 Val Tyr Gly Met Leu Asn Leu Thr Pro Lys Gly Lys Gln Ala Pro
                 185                 190                 195

 Gly Gly His Glu Leu Ser Cys Asp Phe Trp Glu Leu Ile Gly Leu
                 200                 205                 210

 Ala Pro Ala Gly Gly Ala Asp Asn Leu Ile Asn Glu Glu Ser Asp
                 215                 220                 225

 Val Asp Val Gln Leu Asn Asn Arg His Met Met Ile Arg Gly Glu
                 230                 235                 240

 Asn Met Ser Lys Ile Leu Lys Ala Arg Ser Met Val Thr Arg Cys
                 245                 250                 255

 Phe Arg Asp His Phe Phe Asp Arg Gly Tyr Tyr Glu Val Thr Pro
                 260                 265                 270

 Pro Thr Leu Val Gln Thr Gln Val Glu Gly Gly Ala Thr Leu Phe
                 275                 280                 285

 Lys Leu Asp Tyr Phe Gly Glu Glu Ala Phe Leu Thr Gln Ser Ser
                 290                 295                 300

 Gln Leu Tyr Leu Glu Thr Cys Leu Pro Ala Leu Gly Asp Val Phe
                 305                 310                 315

 Cys Ile Ala Gln Ser Tyr Arg Ala Glu Gln Ser Arg Thr Arg Arg
                 320                 325                 330

 His Leu Ala Glu Tyr Thr His Val Glu Ala Glu Cys Pro Phe Leu
                 335                 340                 345

 Thr Phe Asp Asp Leu Leu Asn Arg Leu Glu Asp Leu Val Cys Asp
                 350                 355                 360

 Val Val Asp Arg Ile Leu Lys Ser Pro Ala Gly Ser Ile Val His
                 365                 370                 375

 Glu Leu Asn Pro Asn Phe Gln Pro Pro Lys Arg Pro Phe Lys Arg
                 380                 385                 390

 Met Asn Tyr Ser Asp Ala Ile Val Trp Leu Lys Glu His Asp Val
                 395                 400                 405

 Lys Lys Glu Asp Gly Thr Phe Tyr Glu Phe Gly Glu Asp Ile Pro
                 410                 415                 420

 Glu Ala Pro Glu Arg Leu Met Thr Asp Thr Ile Asn Glu Pro Ile
                 425                 430                 435

 Leu Leu Cys Arg Phe Pro Val Glu Ile Lys Ser Phe Tyr Met Gln
                 440                 445                 450

 Arg Cys Pro Glu Asp Ser Arg Leu Thr Glu Ser Val Asp Val Leu
                 455                 460                 465

 Met Pro Asn Val Gly Glu Ile Val Gly Gly Ser Met Arg Ile Phe
                 470                 475                 480

 Asp Ser Glu Glu Ile Leu Ala Gly Tyr Lys Arg Glu Gly Ile Asp
                 485                 490                 495

 Pro Thr Pro Tyr Tyr Trp Tyr Thr Asp Gln Arg Lys Tyr Gly Thr
                 500                 505                 510

 Cys Pro His Gly Gly Tyr Gly Leu Gly Leu Glu Arg Phe Leu Thr
                 515                 520                 525

 Trp Ile Leu Asn Arg Tyr His Ile Arg Asp Val Cys Leu Tyr Pro
                 530                 535                 540

 Arg Phe Val Gln Arg Cys Thr Pro
                 545

<210> 5
<211> 698
<212> DNA
<213> Homo sapien

<400> 5
 ctttcctttc gctgctgcgg ccgcagccat gagtatgctc aggcttcaga 50

 agaggctcgc ctctagtgtc ctccgctgtg gcaagaagaa ggtctggtta 100

 gaccccaatg agaccaatga aatcgccaat gccaactccc gtcagcagat 150

 ccggaagctc atcaaagatg ggctgatcat ccgcaagcct gtgacggtcc 200

 attcccgggc tcgatgccgg aaaaacacct tggcccgccg gaagggcagg 250

 cacatgggca taggtaagcg gaagggtaca gccaatgccc gaatgccaga 300

 gaaggtcaca tggatgagga gaatgaggat tttgcgccgg ctgctcagaa 350

 gataccgtga atctaagaag atcgatcgcc acatgtatca cagcctgtac 400

 ctgaaggtga aggggaatgt gttcaaaaac aagcggattc tcatggaaca 450

 catccacaag ctgaaggcag acaaggcccg caagaagctc ctggctgacc 500

 aggctgaggc ccgcaggtct aagaccaagg aagcacgcaa gcgccgtgaa 550

 gagcgcctcc aggccaagaa ggaggagatc atcaagactt tatccaagga 600

 ggaagagacc aagaaataaa acctcccact ttgtctgtac atactggcct 650

 ctgtgattac atagatcagc cattaaaata aaacaagcct taatctgc 698

<210> 6
<211> 196
<212> PRT
<213> Homo sapien

<400> 6
 Met Ser Met Leu Arg Leu Gln Lys Arg Leu Ala Ser Ser Val Leu
   1               5                  10                  15

 Arg Cys Gly Lys Lys Lys Val Trp Leu Asp Pro Asn Glu Thr Asn
                  20                  25                  30

 Glu Ile Ala Asn Ala Asn Ser Arg Gln Gln Ile Arg Lys Leu Ile
                  35                  40                  45

 Lys Asp Gly Leu Ile Ile Arg Lys Pro Val Thr Val His Ser Arg
                  50                  55                  60

 Ala Arg Cys Arg Lys Asn Thr Leu Ala Arg Arg Lys Gly Arg His
                  65                  70                  75

 Met Gly Ile Gly Lys Arg Lys Gly Thr Ala Asn Ala Arg Met Pro
                  80                  85                  90

 Glu Lys Val Thr Trp Met Arg Arg Met Arg Ile Leu Arg Arg Leu
                  95                 100                 105

 Leu Arg Arg Tyr Arg Glu Ser Lys Lys Ile Asp Arg His Met Tyr
                 110                 115                 120

 His Ser Leu Tyr Leu Lys Val Lys Gly Asn Val Phe Lys Asn Lys
                 125                 130                 135

 Arg Ile Leu Met Glu His Ile His Lys Leu Lys Ala Asp Lys Ala
                 140                 145                 150

 Arg Lys Lys Leu Leu Ala Asp Gln Ala Glu Ala Arg Arg Ser Lys
                 155                 160                 165

 Thr Lys Glu Ala Arg Lys Arg Arg Glu Glu Arg Leu Gln Ala Lys
                 170                 175                 180

 Lys Glu Glu Ile Ile Lys Thr Leu Ser Lys Glu Glu Glu Thr Lys
                 185                 190                 195

 Lys


<210> 7
<211> 1200
<212> DNA
<213> Homo sapien

<400> 7
 gcccgaccgc tttccgggag actggagtcg aaggccgtga ggtatttttc 50

 taagtcagcc ataatggcag gtgaagaaat taatgaagac tatccagtag 100

 aaattcacga gtatttgtca gcgtttgaga attccattgg tgctgtggat 150

 gagatgctga agaccatgat gtctgtttct agaaatgagt tgttgcagaa 200

 gttggatcca cttgaacaag caaaagtgga tttggtttct gcatacacat 250

 taaattcaat gttttgggtt tatttggcaa cccaaggagt taatcctaag 300

 gaacatccag taaaacagga attggaaaga atcagagtat atatgaacag 350

 agtcaaggaa ataacagaca agaaaaaggc tggcaagctg gacagaggtg 400

 cagcttcaag atttgtaaaa aatgccctct gggaaccaaa atcgaaaaat 450

 gcatcaaaag ttgccaataa aggaaaaagt aaaagttaac tttttggttt 500

 tgatgtacac atattcaaaa agtacatctt cccccccccc cccccccccg 550

 caaaataatt ctgtggcagg gcaaggttta aatgtgtttc ttattaatat 600

 gtaaattcac agtaaatatg taaagctaaa tactttcctc tccaaagatc 650

 attatcttta ttgattagca ctgaggattt taacattgtg atatattata 700

 tatttataat ttaccatctc ttgatgagac tcttatttct ttatataggt 750

 cagtcttgca agtaccattt tataagcagc tgtgaaattt aagtgaaatg 800

 ttctttgtaa acatttgtac tattttaaat gaataatgac cttatgaagt 850

 atgctatctg taggctgaaa ttataggtac atctgttttc actatatgat 900

 attaagaaag cgtgaaatga cttaaatgtt catttttttc tgtatagata 950

 ctttatcatg ttttcatgat tttaggaatt actgctttgt tgatattcaa 1000

 agtgtgaaac taaaacttta tggttgtact ttaattcttg gcatgttgcc 1050

 tctatgtccc atttaaaata aaatacattc tcattaactt tagatgggaa 1100

 ataaggttgt atgttgatgg atgaattttg gcatgatgac tgtactctca 1150

 ataaaggctg aaaatgttgt ataaaaaaaa aaaaaaaaaa aaaaaaaaaa 1200

<210> 8
<211> 141
<212> PRT
<213> Homo sapien

<400> 8
 Met Ala Gly Glu Glu Ile Asn Glu Asp Tyr Pro Val Glu Ile His
   1               5                  10                  15

 Glu Tyr Leu Ser Ala Phe Glu Asn Ser Ile Gly Ala Val Asp Glu
                  20                  25                  30

 Met Leu Lys Thr Met Met Ser Val Ser Arg Asn Glu Leu Leu Gln
                  35                  40                  45

 Lys Leu Asp Pro Leu Glu Gln Ala Lys Val Asp Leu Val Ser Ala
                  50                  55                  60

 Tyr Thr Leu Asn Ser Met Phe Trp Val Tyr Leu Ala Thr Gln Gly
                  65                  70                  75

 Val Asn Pro Lys Glu His Pro Val Lys Gln Glu Leu Glu Arg Ile
                  80                  85                  90

 Arg Val Tyr Met Asn Arg Val Lys Glu Ile Thr Asp Lys Lys Lys
                  95                 100                 105

 Ala Gly Lys Leu Asp Arg Gly Ala Ala Ser Arg Phe Val Lys Asn
                 110                 115                 120

 Ala Leu Trp Glu Pro Lys Ser Lys Asn Ala Ser Lys Val Ala Asn
                 125                 130                 135

 Lys Gly Lys Ser Lys Ser
                 140

<210> 9
<211> 2567
<212> DNA
<213> Homo sapien

<400> 9
 ctccggcgca gtgttgggac tgtctgggta tcggaaagca agcctacgtt 50

 gctcactatt acgtataatc cttttctttt caagatgcct gaggaagtgc 100

 accatggaga ggaggaggtg gagacttttg cctttcaggc agaaattgcc 150

 caactcatgt ccctcatcat caataccttc tattccaaca aggagatttt 200

 ccttcgggag ttgatctcta atgcttctga tgccttggac aagattcgct 250

 atgagagcct gacagaccct tcgaagttgg acagtggtaa agagctgaaa 300

 attgacatca tccccaaccc tcaggaacgt accctgactt tggtagacac 350

 aggcattggc atgaccaaag ctgatctcat aaataatttg ggaaccattg 400

 ccaagtctgg tactaaagca ttcatggagg ctcttcaggc tggtgcagac 450

 atctccatga ttgggcagtt tggtgttggc ttttattctg cctacttggt 500

 ggcagagaaa gtggttgtga tcacaaagca caacgatgat gaacagtatg 550

 cttgggagtc ttctgctgga ggttccttca ctgtgcgtgc tgaccatggt 600

 gagcccattg gcaggggtac caaagtgatc ctccatctta aagaagatca 650

 gacagagtac ctagaagaga ggcgggtcaa agaagtagtg aagaagcatt 700

 ctcagttcat aggctatccc atcacccttt atttggagaa ggaacgagag 750

 aaggaaatta gtgatgatga ggcagaggaa gagaaaggtg agaaagaaga 800

 ggaagataaa gatgatgaag aaaaacccaa gatcgaagat gtgggttcag 850

 atgaggagga tgacagcggt aaggataaga agaagaaaac taagaagatc 900

 aaagagaaat acattgatca ggaagaacta aacaagacca agcctatttg 950

 gaccagaaac cctgatgaca tcacccaaga ggagtatgga gaattctaca 1000

 agagcctcac taatgactgg gaagaccact tggcagtcaa gcacttttct 1050

 gtagaaggtc agttggaatt cagggcattg ctatttattc ctcgtcgggc 1100

 tccctttgac ctttttgaga acaagaagaa aaagaacaac atcaaactct 1150

 atgtccgccg tgtgttcatc atggacagct gtgatgagtt gataccagag 1200

 tatctcaatt ttatccgtgg tgtggttgac tctgaggatc tgcccctgaa 1250

 catctcccga gaaatgctcc agcagagcaa aatcttgaaa gtcattcgca 1300

 aaaacattgt taagaagtgc cttgagctct tctctgagct ggcagaagac 1350

 aaggagaatt acaagaaatt ctatgaggca ttctctaaaa atctcaagct 1400

 tggaatccac gaagactcca ctaaccgccg ccgcctgtct gagctgctgc 1450

 gctatcatac ctcccagtct ggagatgaga tgacatctct gtcagagtat 1500

 gtttctcgca tgaaggagac acagaagtcc atctattaca tcactggtga 1550

 gagcaaagag caggtggcca actcagcttt tgtggagcga gtgcggaaac 1600

 ggggcttcga ggtggtatat atgaccgagc ccattgacga gtactgtgtg 1650

 cagcagctca aggaatttga tgggaagagc ctggtctcag ttaccaagga 1700

 gggtctggag ctgcctgagg atgaggagga gaagaagaag atggaagaga 1750

 gcaaggcaaa gtttgagaac ctctgcaagc tcatgaaaga aatcttagat 1800

 aagaaggttg agaaggtgac aatctccaat agacttgtgt cttcaccttg 1850

 ctgcattgtg accagcacct acggctggac agccaatatg gagcggatca 1900

 tgaaagccca ggcacttcgg gacaactcca ccatgggcta tatgatggcc 1950

 aaaaagcacc tggagatcaa ccctgaccac cccattgtgg agacgctgcg 2000

 gcagaaggct gaggccgaca agaatgataa ggcagttaag gacctggtgg 2050

 tgctgctgtt tgaaaccgcc ctgctatctt ctggcttttc ccttgaggat 2100

 ccccagaccc actccaaccg catctatcgc atgatcaagc taggtctagg 2150

 tattgatgaa gatgaagtgg cagcagagga acccaatgct gcagttcctg 2200

 atgagatccc ccctctcgag ggcgatgagg atgcgtctcg catggaagaa 2250

 gtcgattagg ttaggagttc atagttggaa aacttgtgcc cttgtatagt 2300

 gtccccatgg gctcccactg cagcctcgag tgcccctgtc ccacctggct 2350

 ccccctgctg gtgtctagtg tttttttccc tctcctgtcc ttgtgttgaa 2400

 ggcagtaaac taagggtgtc aagccccatt ccctctctac tcttgacagc 2450

 aggattggat gttgtgtatt gtggtttatt ttattttctt cattttgttc 2500

 tgaaattaaa gtatgcaaaa taaagaatat gccgttttaa aaaaaaaaaa 2550

 aaaaaaaaaa aaaaaaa 2567

<210> 10
<211> 724
<212> PRT
<213> Homo sapien

<400> 10
 Met Pro Glu Glu Val His His Gly Glu Glu Glu Val Glu Thr Phe
   1               5                  10                  15

 Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu Ile Ile Asn
                  20                  25                  30

 Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu Ile Ser
                  35                  40                  45

 Asn Ala Ser Asp Ala Leu Asp Lys Ile Arg Tyr Glu Ser Leu Thr
                  50                  55                  60

 Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu Lys Ile Asp Ile
                  65                  70                  75

 Ile Pro Asn Pro Gln Glu Arg Thr Leu Thr Leu Val Asp Thr Gly
                  80                  85                  90

 Ile Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile
                  95                 100                 105

 Ala Lys Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly
                 110                 115                 120

 Ala Asp Ile Ser Met Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser
                 125                 130                 135

 Ala Tyr Leu Val Ala Glu Lys Val Val Val Ile Thr Lys His Asn
                 140                 145                 150

 Asp Asp Glu Gln Tyr Ala Trp Glu Ser Ser Ala Gly Gly Ser Phe
                 155                 160                 165

 Thr Val Arg Ala Asp His Gly Glu Pro Ile Gly Arg Gly Thr Lys
                 170                 175                 180

 Val Ile Leu His Leu Lys Glu Asp Gln Thr Glu Tyr Leu Glu Glu
                 185                 190                 195

 Arg Arg Val Lys Glu Val Val Lys Lys His Ser Gln Phe Ile Gly
                 200                 205                 210

 Tyr Pro Ile Thr Leu Tyr Leu Glu Lys Glu Arg Glu Lys Glu Ile
                 215                 220                 225

 Ser Asp Asp Glu Ala Glu Glu Glu Lys Gly Glu Lys Glu Glu Glu
                 230                 235                 240

 Asp Lys Asp Asp Glu Glu Lys Pro Lys Ile Glu Asp Val Gly Ser
                 245                 250                 255

 Asp Glu Glu Asp Asp Ser Gly Lys Asp Lys Lys Lys Lys Thr Lys
                 260                 265                 270

 Lys Ile Lys Glu Lys Tyr Ile Asp Gln Glu Glu Leu Asn Lys Thr
                 275                 280                 285

 Lys Pro Ile Trp Thr Arg Asn Pro Asp Asp Ile Thr Gln Glu Glu
                 290                 295                 300

 Tyr Gly Glu Phe Tyr Lys Ser Leu Thr Asn Asp Trp Glu Asp His
                 305                 310                 315

 Leu Ala Val Lys His Phe Ser Val Glu Gly Gln Leu Glu Phe Arg
                 320                 325                 330

 Ala Leu Leu Phe Ile Pro Arg Arg Ala Pro Phe Asp Leu Phe Glu
                 335                 340                 345

 Asn Lys Lys Lys Lys Asn Asn Ile Lys Leu Tyr Val Arg Arg Val
                 350                 355                 360

 Phe Ile Met Asp Ser Cys Asp Glu Leu Ile Pro Glu Tyr Leu Asn
                 365                 370                 375

 Phe Ile Arg Gly Val Val Asp Ser Glu Asp Leu Pro Leu Asn Ile
                 380                 385                 390

 Ser Arg Glu Met Leu Gln Gln Ser Lys Ile Leu Lys Val Ile Arg
                 395                 400                 405

 Lys Asn Ile Val Lys Lys Cys Leu Glu Leu Phe Ser Glu Leu Ala
                 410                 415                 420

 Glu Asp Lys Glu Asn Tyr Lys Lys Phe Tyr Glu Ala Phe Ser Lys
                 425                 430                 435

 Asn Leu Lys Leu Gly Ile His Glu Asp Ser Thr Asn Arg Arg Arg
                 440                 445                 450

 Leu Ser Glu Leu Leu Arg Tyr His Thr Ser Gln Ser Gly Asp Glu
                 455                 460                 465

 Met Thr Ser Leu Ser Glu Tyr Val Ser Arg Met Lys Glu Thr Gln
                 470                 475                 480

 Lys Ser Ile Tyr Tyr Ile Thr Gly Glu Ser Lys Glu Gln Val Ala
                 485                 490                 495

 Asn Ser Ala Phe Val Glu Arg Val Arg Lys Arg Gly Phe Glu Val
                 500                 505                 510

 Val Tyr Met Thr Glu Pro Ile Asp Glu Tyr Cys Val Gln Gln Leu
                 515                 520                 525

 Lys Glu Phe Asp Gly Lys Ser Leu Val Ser Val Thr Lys Glu Gly
                 530                 535                 540

 Leu Glu Leu Pro Glu Asp Glu Glu Glu Lys Lys Lys Met Glu Glu
                 545                 550                 555

 Ser Lys Ala Lys Phe Glu Asn Leu Cys Lys Leu Met Lys Glu Ile
                 560                 565                 570

 Leu Asp Lys Lys Val Glu Lys Val Thr Ile Ser Asn Arg Leu Val
                 575                 580                 585

 Ser Ser Pro Cys Cys Ile Val Thr Ser Thr Tyr Gly Trp Thr Ala
                 590                 595                 600

 Asn Met Glu Arg Ile Met Lys Ala Gln Ala Leu Arg Asp Asn Ser
                 605                 610                 615

 Thr Met Gly Tyr Met Met Ala Lys Lys His Leu Glu Ile Asn Pro
                 620                 625                 630

 Asp His Pro Ile Val Glu Thr Leu Arg Gln Lys Ala Glu Ala Asp
                 635                 640                 645

 Lys Asn Asp Lys Ala Val Lys Asp Leu Val Val Leu Leu Phe Glu
                 650                 655                 660

 Thr Ala Leu Leu Ser Ser Gly Phe Ser Leu Glu Asp Pro Gln Thr
                 665                 670                 675

 His Ser Asn Arg Ile Tyr Arg Met Ile Lys Leu Gly Leu Gly Ile
                 680                 685                 690

 Asp Glu Asp Glu Val Ala Ala Glu Glu Pro Asn Ala Ala Val Pro
                 695                 700                 705

 Asp Glu Ile Pro Pro Leu Glu Gly Asp Glu Asp Ala Ser Arg Met
                 710                 715                 720

 Glu Glu Val Asp


<210> 11
<211> 632
<212> DNA
<213> Homo sapien

<400> 11
 ctctcggctt tcggctcgga ggaggccaag gtgcaacttc cttcggtcgt 50

 cccgaatccg ggttcatccg acaccagccg cctccaccat gccgccgaag 100

 ttcgacccca acgagatcaa agtcgtatac ctgaggtgca ccggaggtga 150

 agtcggtgcc acttctgccc tggcccccaa gatcggcccc ctgggtctgt 200

 ctccaaaaaa agttggtgat gacattgcca aggcaacggg tgactggaag 250

 ggcctgagga ttacagtgaa actgaccatt cagaacagac aggcccagat 300

 tgaggtggtg ccttctgcct ctgccctgat catcaaagcc ctcaaggaac 350

 caccaagaga cagaaagaaa cagaaaaaca ttaaacacag tgggaatatc 400

 acttttgatg agattgtcaa cattgctcga cagatgcggc accgatcctt 450

 agccagagaa ctctctggaa ccattaaaga gatcctgggg actgcccagt 500

 cagtgggctg taatgttgat ggccgccatc ctcatgacat catcgatgac 550

 atcaacagtg gtgctgtgga atgcccagcc agttaagcac aaaggaaaac 600

 atttcaataa aggatcattt gacaactggt ga 632

<210> 12
<211> 165
<212> PRT
<213> Homo sapien

<400> 12
 Met Pro Pro Lys Phe Asp Pro Asn Glu Ile Lys Val Val Tyr Leu
   1               5                  10                  15

 Arg Cys Thr Gly Gly Glu Val Gly Ala Thr Ser Ala Leu Ala Pro
                  20                  25                  30

 Lys Ile Gly Pro Leu Gly Leu Ser Pro Lys Lys Val Gly Asp Asp
                  35                  40                  45

 Ile Ala Lys Ala Thr Gly Asp Trp Lys Gly Leu Arg Ile Thr Val
                  50                  55                  60

 Lys Leu Thr Ile Gln Asn Arg Gln Ala Gln Ile Glu Val Val Pro
                  65                  70                  75

 Ser Ala Ser Ala Leu Ile Ile Lys Ala Leu Lys Glu Pro Pro Arg
                  80                  85                  90

 Asp Arg Lys Lys Gln Lys Asn Ile Lys His Ser Gly Asn Ile Thr
                  95                 100                 105

 Phe Asp Glu Ile Val Asn Ile Ala Arg Gln Met Arg His Arg Ser
                 110                 115                 120

 Leu Ala Arg Glu Leu Ser Gly Thr Ile Lys Glu Ile Leu Gly Thr
                 125                 130                 135

 Ala Gln Ser Val Gly Cys Asn Val Asp Gly Arg His Pro His Asp
                 140                 145                 150

 Ile Ile Asp Asp Ile Asn Ser Gly Ala Val Glu Cys Pro Ala Ser
                 155                 160                 165

<210> 13
<211> 3301
<212> DNA
<213> Homo sapien

<400> 13
 aggagccagg aagagagctg tgaccagcag cgtcccttat tcgcttggcc 50

 ttggttcctg tttgcactgg ctacagcagg gcactggccc ctactgtcac 100

 cgccacctac acaaagaccc tatctctgag cgctgcagcc tactgttcag 150

 ccccaggttt gaggatggat gccctggacg cttcgaagct actggatgag 200

 gagctgtatt caagacagct gtatgtgctg ggctcacctg ccatgcagag 250

 gattcaggga gccagggtcc tggtgtcagg cctgcagggc ctgggggccg 300

 aggtggccaa gaacttggtt ctgatgggtg tgggcagcct cactctgcat 350

 gatccccacc ccacctgctg gtccgacctg gctgcccagt ttctcctctc 400

 agagcaggac ttggaaagga gcagagccga ggcctctcaa gagctcttgg 450

 ctcagctcaa cagagctgtc caggtcgtcg tgcacacggg tgacatcact 500

 gaggacctgc tgttggactt ccaggtggtg gtgctgactg ctgcaaagct 550

 ggaggagcag ctgaaggtgg gcaccttgtg tcataagcat ggagtttgct 600

 ttctggcggc tgacacccgg ggcctcgtgg ggcagttgtt ctgtgacttt 650

 ggtgaggact tcactgtgca ggaccccaca gaggcagaac ccctgacagc 700

 tgccatccag cacatctccc agggctcccc tggcattctc actctgagga 750

 aaggggccaa tacccactac ttccgtgatg gagacttggt gactttctcg 800

 ggaattgagg gaatggttga gctcaacgac tgtgatcccc ggtctatcca 850

 cgtgcgggag gatgggtccc tggagattgg agacacaaca actttctctc 900

 ggtacttgcg tggtggggct atcactgaag tcaagagacc caagactgtg 950

 agacataagt ccctggacac agccctgctc cagccccatg tggtggccca 1000

 gagctcccag gaagttcacc atgcccactg cctgcatcag gccttctgtg 1050

 cactgcacaa gttccagcac ctccatggcc ggccacccca gccctgggat 1100

 cctgttgatg cagagactgt ggtgggcctg gcccgggacc tggaaccact 1150

 gaagcggaca gaggaagagc cactggaaga gccactggat gaggccctag 1200

 tgcggacagt cgccctaagc agtgcaaggt gtcttgagcc tatggtggca 1250

 tgctgggtca gtagctgccc aggaagtgct gaaggcaatc tccagaagtt 1300

 catgcctctg gaccagtggc tttactttga tgccctcgat tgtcttccgg 1350

 aagatgggga gctccttccc agtcctgagg actgtgccct gagaggcagc 1400

 cgctatgatg ggcaaattgc agtgtttggg gctggttttc aggagaaact 1450

 gagacgccag cactacctcc tggtgggcgc tggtgccatt ggttgtgagc 1500

 tgctcaaagt ctttgcccta gtgggactgg gggccgggaa cagcgggggc 1550

 ttgactgttg ttgacatgga ccacatagag cgctccaatc tcagccgtca 1600

 gttcctcttc aggtcccagg acgttggtag acccaaggca gaggtggctg 1650

 cagcagctgc ccggggcctg aacccagact tacaggtgat cccgctcacc 1700

 tacccactgg atcccaccac agagcacatc tatggggata actttttctc 1750

 ccgtgtggat ggtgtggctg ctgccctgga cagtttccag gcccggcgct 1800

 atgtggctgc tcgttgcacc cactatctga agccactgct ggaggcaggc 1850

 acatcgggca cctggggcag tgctacagta ttcatgccac atgtgactga 1900

 ggcctacaga gcccctgcct cagctgcagc ttctgaggat gccccctacc 1950

 ctgtctgtac cgtgcggtac ttccctagca cagccgagca caccctgcag 2000

 tgggcccggc atgagtttga agaactcttc cgactgtctg cagagaccat 2050

 caaccaccac caacaggcac acacctccct ggcagacatg gatgagccac 2100

 agacactcac cttactgaag ccagtgcttg gggtcctgag agtgcgtcca 2150

 cagaactggc aagactgtgt ggcgtgggct cttggccact ggaaactctg 2200

 ctttcattat ggcatcaaac agctgctgag gcacttccca cctaataaag 2250

 tgcttgagga tggaactccc ttctggtcag gtcccaaaca gtgtccccag 2300

 cccttggagt ttgacaccaa ccaagacaca cacctcctct acgtactggc 2350

 agctgccaac ctgtatgccc agatgcatgg gctgcctggc tcacaggact 2400

 ggactgcact cagggagctg ctgaagctgc tgccacagcc tgacccccaa 2450

 cagatggccc ccatctttgc tagtaatcta gagctggctt cggcttctgc 2500

 tgagtttggc cctgagcagc agaaggaact gaacaaagcc ctggaagtct 2550

 ggagtgtggg ccctcccctg aagcctctga tgtttgagaa ggatgatgac 2600

 agcaacttcc atgtggactt tgtggtagcg gcagctagcc tgagatgtca 2650

 gaactacggg attccaccgg tcaaccgtgc ccagagcaag cgaattgtgg 2700

 gccagattat cccagccatt gccaccacta cagcagctgt ggcaggcctg 2750

 ttgggcctgg agctgtataa ggtggtgagt gggccacggc ctcgtagtgc 2800

 ctttcgccac agctacctac atctggctga aaactacctc atccgctata 2850

 tgccttttgc cccagccatc cagacgttcc atcacctgaa gtggacctct 2900

 tgggaccgtc tgaaggtacc agctgggcag cctgagagga ccctggagtc 2950

 gctgctggct catcttcagg agcagcacgg gttgagggtg aggatcctgc 3000

 tgcacggctc agccctgctc tatgcggccg gatggtcacc tgaaaagcag 3050

 gcccagcacc tgcccctcag ggtgacagaa ctggttcagc agctgacagg 3100

 ccaggcacct gctcctgggc agcgggtgtt ggtgctagag ctgagctgtg 3150

 agggtgacga cgaggacact gccttcccac ctctgcacta tgagctgtga 3200

 caaggcagcc accctgtcac ctagctcaat ggagccccgg atcccaagcc 3250

 ctgcattgta agcccacagt aggcactcaa taattgcttg ttaaaggaag 3300

 g 3301

<210> 14
<211> 1011
<212> PRT
<213> Homo sapien

<400> 14
 Met Asp Ala Leu Asp Ala Ser Lys Leu Leu Asp Glu Glu Leu Tyr
   1               5                  10                  15

 Ser Arg Gln Leu Tyr Val Leu Gly Ser Pro Ala Met Gln Arg Ile
                  20                  25                  30

 Gln Gly Ala Arg Val Leu Val Ser Gly Leu Gln Gly Leu Gly Ala
                  35                  40                  45

 Glu Val Ala Lys Asn Leu Val Leu Met Gly Val Gly Ser Leu Thr
                  50                  55                  60

 Leu His Asp Pro His Pro Thr Cys Trp Ser Asp Leu Ala Ala Gln
                  65                  70                  75

 Phe Leu Leu Ser Glu Gln Asp Leu Glu Arg Ser Arg Ala Glu Ala
                  80                  85                  90

 Ser Gln Glu Leu Leu Ala Gln Leu Asn Arg Ala Val Gln Val Val
                  95                 100                 105

 Val His Thr Gly Asp Ile Thr Glu Asp Leu Leu Leu Asp Phe Gln
                 110                 115                 120

 Val Val Val Leu Thr Ala Ala Lys Leu Glu Glu Gln Leu Lys Val
                 125                 130                 135

 Gly Thr Leu Cys His Lys His Gly Val Cys Phe Leu Ala Ala Asp
                 140                 145                 150

 Thr Arg Gly Leu Val Gly Gln Leu Phe Cys Asp Phe Gly Glu Asp
                 155                 160                 165

 Phe Thr Val Gln Asp Pro Thr Glu Ala Glu Pro Leu Thr Ala Ala
                 170                 175                 180

 Ile Gln His Ile Ser Gln Gly Ser Pro Gly Ile Leu Thr Leu Arg
                 185                 190                 195

 Lys Gly Ala Asn Thr His Tyr Phe Arg Asp Gly Asp Leu Val Thr
                 200                 205                 210

 Phe Ser Gly Ile Glu Gly Met Val Glu Leu Asn Asp Cys Asp Pro
                 215                 220                 225

 Arg Ser Ile His Val Arg Glu Asp Gly Ser Leu Glu Ile Gly Asp
                 230                 235                 240

 Thr Thr Thr Phe Ser Arg Tyr Leu Arg Gly Gly Ala Ile Thr Glu
                 245                 250                 255

 Val Lys Arg Pro Lys Thr Val Arg His Lys Ser Leu Asp Thr Ala
                 260                 265                 270

 Leu Leu Gln Pro His Val Val Ala Gln Ser Ser Gln Glu Val His
                 275                 280                 285

 His Ala His Cys Leu His Gln Ala Phe Cys Ala Leu His Lys Phe
                 290                 295                 300

 Gln His Leu His Gly Arg Pro Pro Gln Pro Trp Asp Pro Val Asp
                 305                 310                 315

 Ala Glu Thr Val Val Gly Leu Ala Arg Asp Leu Glu Pro Leu Lys
                 320                 325                 330

 Arg Thr Glu Glu Glu Pro Leu Glu Glu Pro Leu Asp Glu Ala Leu
                 335                 340                 345

 Val Arg Thr Val Ala Leu Ser Ser Ala Arg Cys Leu Glu Pro Met
                 350                 355                 360

 Val Ala Cys Trp Val Ser Ser Cys Pro Gly Ser Ala Glu Gly Asn
                 365                 370                 375

 Leu Gln Lys Phe Met Pro Leu Asp Gln Trp Leu Tyr Phe Asp Ala
                 380                 385                 390

 Leu Asp Cys Leu Pro Glu Asp Gly Glu Leu Leu Pro Ser Pro Glu
                 395                 400                 405

 Asp Cys Ala Leu Arg Gly Ser Arg Tyr Asp Gly Gln Ile Ala Val
                 410                 415                 420

 Phe Gly Ala Gly Phe Gln Glu Lys Leu Arg Arg Gln His Tyr Leu
                 425                 430                 435

 Leu Val Gly Ala Gly Ala Ile Gly Cys Glu Leu Leu Lys Val Phe
                 440                 445                 450

 Ala Leu Val Gly Leu Gly Ala Gly Asn Ser Gly Gly Leu Thr Val
                 455                 460                 465

 Val Asp Met Asp His Ile Glu Arg Ser Asn Leu Ser Arg Gln Phe
                 470                 475                 480

 Leu Phe Arg Ser Gln Asp Val Gly Arg Pro Lys Ala Glu Val Ala
                 485                 490                 495

 Ala Ala Ala Ala Arg Gly Leu Asn Pro Asp Leu Gln Val Ile Pro
                 500                 505                 510

 Leu Thr Tyr Pro Leu Asp Pro Thr Thr Glu His Ile Tyr Gly Asp
                 515                 520                 525

 Asn Phe Phe Ser Arg Val Asp Gly Val Ala Ala Ala Leu Asp Ser
                 530                 535                 540

 Phe Gln Ala Arg Arg Tyr Val Ala Ala Arg Cys Thr His Tyr Leu
                 545                 550                 555

 Lys Pro Leu Leu Glu Ala Gly Thr Ser Gly Thr Trp Gly Ser Ala
                 560                 565                 570

 Thr Val Phe Met Pro His Val Thr Glu Ala Tyr Arg Ala Pro Ala
                 575                 580                 585

 Ser Ala Ala Ala Ser Glu Asp Ala Pro Tyr Pro Val Cys Thr Val
                 590                 595                 600

 Arg Tyr Phe Pro Ser Thr Ala Glu His Thr Leu Gln Trp Ala Arg
                 605                 610                 615

 His Glu Phe Glu Glu Leu Phe Arg Leu Ser Ala Glu Thr Ile Asn
                 620                 625                 630

 His His Gln Gln Ala His Thr Ser Leu Ala Asp Met Asp Glu Pro
                 635                 640                 645

 Gln Thr Leu Thr Leu Leu Lys Pro Val Leu Gly Val Leu Arg Val
                 650                 655                 660

 Arg Pro Gln Asn Trp Gln Asp Cys Val Ala Trp Ala Leu Gly His
                 665                 670                 675

 Trp Lys Leu Cys Phe His Tyr Gly Ile Lys Gln Leu Leu Arg His
                 680                 685                 690

 Phe Pro Pro Asn Lys Val Leu Glu Asp Gly Thr Pro Phe Trp Ser
                 695                 700                 705

 Gly Pro Lys Gln Cys Pro Gln Pro Leu Glu Phe Asp Thr Asn Gln
                 710                 715                 720

 Asp Thr His Leu Leu Tyr Val Leu Ala Ala Ala Asn Leu Tyr Ala
                 725                 730                 735

 Gln Met His Gly Leu Pro Gly Ser Gln Asp Trp Thr Ala Leu Arg
                 740                 745                 750

 Glu Leu Leu Lys Leu Leu Pro Gln Pro Asp Pro Gln Gln Met Ala
                 755                 760                 765

 Pro Ile Phe Ala Ser Asn Leu Glu Leu Ala Ser Ala Ser Ala Glu
                 770                 775                 780

 Phe Gly Pro Glu Gln Gln Lys Glu Leu Asn Lys Ala Leu Glu Val
                 785                 790                 795

 Trp Ser Val Gly Pro Pro Leu Lys Pro Leu Met Phe Glu Lys Asp
                 800                 805                 810

 Asp Asp Ser Asn Phe His Val Asp Phe Val Val Ala Ala Ala Ser
                 815                 820                 825

 Leu Arg Cys Gln Asn Tyr Gly Ile Pro Pro Val Asn Arg Ala Gln
                 830                 835                 840

 Ser Lys Arg Ile Val Gly Gln Ile Ile Pro Ala Ile Ala Thr Thr
                 845                 850                 855

 Thr Ala Ala Val Ala Gly Leu Leu Gly Leu Glu Leu Tyr Lys Val
                 860                 865                 870

 Val Ser Gly Pro Arg Pro Arg Ser Ala Phe Arg His Ser Tyr Leu
                 875                 880                 885

 His Leu Ala Glu Asn Tyr Leu Ile Arg Tyr Met Pro Phe Ala Pro
                 890                 895                 900

 Ala Ile Gln Thr Phe His His Leu Lys Trp Thr Ser Trp Asp Arg
                 905                 910                 915

 Leu Lys Val Pro Ala Gly Gln Pro Glu Arg Thr Leu Glu Ser Leu
                 920                 925                 930

 Leu Ala His Leu Gln Glu Gln His Gly Leu Arg Val Arg Ile Leu
                 935                 940                 945

 Leu His Gly Ser Ala Leu Leu Tyr Ala Ala Gly Trp Ser Pro Glu
                 950                 955                 960

 Lys Gln Ala Gln His Leu Pro Leu Arg Val Thr Glu Leu Val Gln
                 965                 970                 975

 Gln Leu Thr Gly Gln Ala Pro Ala Pro Gly Gln Arg Val Leu Val
                 980                 985                 990

 Leu Glu Leu Ser Cys Glu Gly Asp Asp Glu Asp Thr Ala Phe Pro
                 995                1000                1005

 Pro Leu His Tyr Glu Leu
                1010

<210> 15
<211> 1929
<212> DNA
<213> Homo sapien

<400> 15
 acccccgcac ccagctccgc agaccggcgg gcgcgcgcgg gctctggagg 50

 ccacgggcat gatgcttcgg gtcctggtgg gggctgtcct ccctgccatg 100

 ctactggctg ccccaccacc catcaacaag ctggcactgt tcccagataa 150

 gagtgcctgg tgcgaagcca agaacatcac ccagatcgtg ggccacagcg 200

 gctgtgaggc caagtccatc cagaacaggg cgtgcctagg acagtgcttc 250

 agctacagcg tccccaacac cttcccacag tccacagagt ccctggttca 300

 ctgtgactcc tgcatgccag cccagtccat gtgggagatt gtgacgctgg 350

 agtgcccggg ccacgaggag gtgcccaggg tggacaagct ggtggagaag 400

 atcctgcact gtagctgcca ggcctgcggc aaggagccta gtcacgaggg 450

 gctgagcgtc tatgtgcagg gcgaggacgg gccgggatcc cagcccggca 500

 cccaccctca cccccatccc cacccccatc ctggcgggca gacccctgag 550

 cccgaggacc cccctggggc cccccacaca gaggaagagg gggctgagga 600

 ctgaggcccc cccaactctt cctcccctct catccccctg tggaatgttg 650

 ggtctcactc tctggggaag tcaggggaga agctgaagcc cccctttggc 700

 actggatgga cttggcttca gactcggact tgaatgctgc ccggttgcca 750

 tggagatctg aaggggcggg gttagagcca agctgcacaa tttaatatat 800

 tcaagagtgg ggggaggaag cagaggtctt cagggctctt tttttggggg 850

 gggggtggtc tcttcctgtc tggcttctag agatgtgcct gtgggagggg 900

 gaggaagttg gctgagccat tgagtgctgg gggaggccat ccaagatggc 950

 atgaatcggg ctaaggtccc tgggggtgca gatggtactg ctgaggtccc 1000

 gggcttagtg tgagcatctt gccagcctca ggcttgaggg agggctgggc 1050

 tagaaagacc actggcagaa acaggaggct ccggccccac aggtttcccc 1100

 aaggcctctc accccacttc ccatctccag ggaagcgtcg ccccagtggc 1150

 actgaagtgg ccctccctca gcggaggggt ttgggagtca ggcctgggca 1200

 ggaccctgct gactcgtggc gcgggagctg ggagccaggc tctccgggcc 1250

 tttctctggc ttccttggct tgcctggtgg gggaagggga ggaggggaag 1300

 aaggaaaggg aagagtcttc caaggccaga gggaggggga caacccccca 1350

 agaccatccc tgaagacgag catccccctc ctctccctgt tagaaatgtt 1400

 agtgccccgc actgtgcccc aagttctagg ccccccagaa agctgtcaga 1450

 gccggccgcc ttctcccctc tcccagggat gctctttgta aatatcggat 1500

 gggtgtggga gtgaggggtt acctccctcg ccccaaggtt ccagaggccc 1550

 taggcgggat gggctcgctg aacctcgagg aactccagga cgaggaggac 1600

 atgggacttg cgtggacagt cagggttcac ttgggctctc tctagctccc 1650

 caattctgcc tgcctcctcc ctcccagctg cactttaacc ctagaaggtg 1700

 gggacctggg gggagggaca gggcaggcgg gcccatgaag aaagcccctc 1750

 gttgcccagc actgtctgcg tctgctcttc tgtgcccagg gtggctgcca 1800

 gcccactgcc tcctgcctgg ggtggcctgg ccctcctggc tgttgcgacg 1850

 cgggcttctg gagcttgtca ccattggaca gtctccctga tggaccctca 1900

 gtcttctcat gaataaattc ttcggaatt 1929

<210> 16
<211> 180
<212> PRT
<213> Homo sapien

<400> 16
 Met Leu Arg Val Leu Val Gly Ala Val Leu Pro Ala Met Leu Leu
   1               5                  10                  15

 Ala Ala Pro Pro Pro Ile Asn Lys Leu Ala Leu Phe Pro Asp Lys
                  20                  25                  30

 Ser Ala Trp Cys Glu Ala Lys Asn Ile Thr Gln Ile Val Gly His
                  35                  40                  45

 Ser Gly Cys Glu Ala Lys Ser Ile Gln Asn Arg Ala Cys Leu Gly
                  50                  55                  60

 Gln Cys Phe Ser Tyr Ser Val Pro Asn Thr Phe Pro Gln Ser Thr
                  65                  70                  75

 Glu Ser Leu Val His Cys Asp Ser Cys Met Pro Ala Gln Ser Met
                  80                  85                  90

 Trp Glu Ile Val Thr Leu Glu Cys Pro Gly His Glu Glu Val Pro
                  95                 100                 105

 Arg Val Asp Lys Leu Val Glu Lys Ile Leu His Cys Ser Cys Gln
                 110                 115                 120

 Ala Cys Gly Lys Glu Pro Ser His Glu Gly Leu Ser Val Tyr Val
                 125                 130                 135

 Gln Gly Glu Asp Gly Pro Gly Ser Gln Pro Gly Thr His Pro His
                 140                 145                 150

 Pro His Pro His Pro His Pro Gly Gly Gln Thr Pro Glu Pro Glu
                 155                 160                 165

 Asp Pro Pro Gly Ala Pro His Thr Glu Glu Glu Gly Ala Glu Asp
                 170                 175                 180

<210> 17
<211> 2739
<212> DNA
<213> Homo sapien

<400> 17
 cgactgcagc ctgggtttta ttcttggcct ggccctgacc gggagctggc 50

 ccctcggctg cttctctggc tcggggggga ctttctctgg ctcagatccg 100

 gacccctgaa ctggacctgg ttgtcgtccc cccgcttctc agccccctct 150

 ggggttcctc tctcctctcc gcccactctt tgctcactgc cccatgtccc 200

 tcggtcagtc ggcctgtctg ttcctctcta tagctcggtc aaggagtgtg 250

 atgactggcg agcagatggc tgccttccat ccatcgtcca cccccaaccc 300

 gctggagagg cccatcaaga tgggctggct gaagaagcag aggtccatcg 350

 tgaagaactg gcagcagagg tactttgtgc tgagggcgca gcagctctac 400

 tactacaagg atgaagagga cacgaagccc cagggctgca tgtatctacc 450

 aggatgtaca atcaaggaga tcgccacaaa cccagaagaa gctgggaagt 500

 ttgtctttga aatcattcca gcctcatggg accagaatcg catgggacag 550

 gactcctatg tcctcatggc cagctctcag gcggagatgg aggagtgggt 600

 taaattcctc aggagagttg ctggcacacc ctgtggagtg tttggccagc 650

 gcttggatga gactgtggcc tatgaacaga aattcggccc ccatctggtg 700

 cccatcctgg tggagaaatg tgcagagttc atcctggagc acggccggaa 750

 tgaagagggc atcttccgtc tgcctgggca ggacaacctg gtgaagcagc 800

 tgagagacgc ttttgatgct ggggagcggc cctcctttga cagagacaca 850

 gatgtgcaca ctgtggcttc cctgttaaag ctctacctcc gagacctccc 900

 agagcccgtg gttccctgga gccagtacga agggttcctg ctctgtgggc 950

 agctcacgaa tgcggatgag gcaaaggctc agcaggagtt gatgaagcag 1000

 ctctccatcc ttcctcgtga caactatagt ctcctgagct acatctgcag 1050

 gttcctacat gaaatacagc tgaactgtgc tgttaacaag atgagtgtgg 1100

 acaacctggc tactgtgatt ggtgtgaatc tcatcaggtc gaaggtcgaa 1150

 gaccctgccg tgatcatgag agggactcct cagatccaaa gagtgatgac 1200

 tatgatgatc agagaccatg aagtcctctt ccccaagtcc aaggatatac 1250

 ccctgtcacc ccctgcccag aaaaatgacc ccaagaaagc tccagtggcc 1300

 cgaagctctg taggctggga tgccactgaa gacctccgaa tttctaggac 1350

 agacagcttc agtagcatga caagcgactc tgatacaacc agccccaccg 1400

 gacagcagcc gagcgatgcg tttccggagg acagcagcaa agtacccagg 1450

 gaaaagccag gagactggaa aatgcaatct cgtaaaagga ctcaaacact 1500

 ccctaaccgg aaatgtttct tgacatcagc ttttcagggt gccaacagca 1550

 gcaaaatgga gatctttaaa aatgaattct ggtcgccttc ctcagaggct 1600

 aaggcagggg aagggcacag gagaacgatg tctcaagact tgcgccaact 1650

 ttctgactcc caacggactt ccacctacga taacgtccct tccctgccag 1700

 ggtcccctgg ggaggaagcc agtgcactct cttcccaagc ctgtgactcc 1750

 aagggagata ctcttgccag tccaaactct gaaactgggc ctggaaaaaa 1800

 gaactctgga gaagaggaaa ttgattcttt gcagaggatg gtccaagagc 1850

 tacgaaagga aatagaaaca cagaagcaaa tgtatgagga acagattaaa 1900

 aaccttgaga aggaaaatta tgacgtttgg gctaaagtgg tgaggctcaa 1950

 tgaagaactg gagaaggaaa agaagaagtc tgcagcccta gagatcagcc 2000

 tccgcaacat ggagcgctcc cgggaggatg ttgagaagag gaacaaggcc 2050

 ttggaagaag aagtcaagga atttgtcaaa tccatgaagg aacccaagac 2100

 cgaggcttaa gggtcccagg agtactgcag ggacagcccc agagaggccc 2150

 aactctggcc cctttctcag tgctatctga tgacggggaa acaaaattat 2200

 tctctgagag ggaaaggaca tttgagggaa acatcaaatt tccccataaa 2250

 taaatgaatg gagtttgcag gaaggtgagg gtgagcagag atgtgtgtgg 2300

 acatctctga ccatccatcg ctgtattcaa atggattgtt ctattccatt 2350

 ctggtctcag gcatgaccac gtccagtgaa gacatttgag gcagcacatc 2400

 tcaggaccca ggcaatagac tggccccaac tcaggctgga ctaaggtgtg 2450

 attaattctt tgttttttgt gtggaacagc tcaccttgtc agacagcctc 2500

 agggcatctc tgagacacag gggcagaaaa tgacattcat cttttgagtc 2550

 ctcatccatg gagtgctgtg tttggggggc tgcatctgct gaagcgagaa 2600

 ccccattctg ccaccccacc aggatgccca ttctccagga cttctccaac 2650

 ttactattag actaaaccag aacaagcaac aaactgtatt tatgcaagca 2700

 aaattgatga gaaaattata ttcaaataaa gcaaaattt 2739

<210> 18
<211> 638
<212> PRT
<213> Homo sapien

<400> 18
 Met Ser Leu Gly Gln Ser Ala Cys Leu Phe Leu Ser Ile Ala Arg
   1               5                  10                  15

 Ser Arg Ser Val Met Thr Gly Glu Gln Met Ala Ala Phe His Pro
                  20                  25                  30

 Ser Ser Thr Pro Asn Pro Leu Glu Arg Pro Ile Lys Met Gly Trp
                  35                  40                  45

 Leu Lys Lys Gln Arg Ser Ile Val Lys Asn Trp Gln Gln Arg Tyr
                  50                  55                  60

 Phe Val Leu Arg Ala Gln Gln Leu Tyr Tyr Tyr Lys Asp Glu Glu
                  65                  70                  75

 Asp Thr Lys Pro Gln Gly Cys Met Tyr Leu Pro Gly Cys Thr Ile
                  80                  85                  90

 Lys Glu Ile Ala Thr Asn Pro Glu Glu Ala Gly Lys Phe Val Phe
                  95                 100                 105

 Glu Ile Ile Pro Ala Ser Trp Asp Gln Asn Arg Met Gly Gln Asp
                 110                 115                 120

 Ser Tyr Val Leu Met Ala Ser Ser Gln Ala Glu Met Glu Glu Trp
                 125                 130                 135

 Val Lys Phe Leu Arg Arg Val Ala Gly Thr Pro Cys Gly Val Phe
                 140                 145                 150

 Gly Gln Arg Leu Asp Glu Thr Val Ala Tyr Glu Gln Lys Phe Gly
                 155                 160                 165

 Pro His Leu Val Pro Ile Leu Val Glu Lys Cys Ala Glu Phe Ile
                 170                 175                 180

 Leu Glu His Gly Arg Asn Glu Glu Gly Ile Phe Arg Leu Pro Gly
                 185                 190                 195

 Gln Asp Asn Leu Val Lys Gln Leu Arg Asp Ala Phe Asp Ala Gly
                 200                 205                 210

 Glu Arg Pro Ser Phe Asp Arg Asp Thr Asp Val His Thr Val Ala
                 215                 220                 225

 Ser Leu Leu Lys Leu Tyr Leu Arg Asp Leu Pro Glu Pro Val Val
                 230                 235                 240

 Pro Trp Ser Gln Tyr Glu Gly Phe Leu Leu Cys Gly Gln Leu Thr
                 245                 250                 255

 Asn Ala Asp Glu Ala Lys Ala Gln Gln Glu Leu Met Lys Gln Leu
                 260                 265                 270

 Ser Ile Leu Pro Arg Asp Asn Tyr Ser Leu Leu Ser Tyr Ile Cys
                 275                 280                 285

 Arg Phe Leu His Glu Ile Gln Leu Asn Cys Ala Val Asn Lys Met
                 290                 295                 300

 Ser Val Asp Asn Leu Ala Thr Val Ile Gly Val Asn Leu Ile Arg
                 305                 310                 315

 Ser Lys Val Glu Asp Pro Ala Val Ile Met Arg Gly Thr Pro Gln
                 320                 325                 330

 Ile Gln Arg Val Met Thr Met Met Ile Arg Asp His Glu Val Leu
                 335                 340                 345

 Phe Pro Lys Ser Lys Asp Ile Pro Leu Ser Pro Pro Ala Gln Lys
                 350                 355                 360

 Asn Asp Pro Lys Lys Ala Pro Val Ala Arg Ser Ser Val Gly Trp
                 365                 370                 375

 Asp Ala Thr Glu Asp Leu Arg Ile Ser Arg Thr Asp Ser Phe Ser
                 380                 385                 390

 Ser Met Thr Ser Asp Ser Asp Thr Thr Ser Pro Thr Gly Gln Gln
                 395                 400                 405

 Pro Ser Asp Ala Phe Pro Glu Asp Ser Ser Lys Val Pro Arg Glu
                 410                 415                 420

 Lys Pro Gly Asp Trp Lys Met Gln Ser Arg Lys Arg Thr Gln Thr
                 425                 430                 435

 Leu Pro Asn Arg Lys Cys Phe Leu Thr Ser Ala Phe Gln Gly Ala
                 440                 445                 450

 Asn Ser Ser Lys Met Glu Ile Phe Lys Asn Glu Phe Trp Ser Pro
                 455                 460                 465

 Ser Ser Glu Ala Lys Ala Gly Glu Gly His Arg Arg Thr Met Ser
                 470                 475                 480

 Gln Asp Leu Arg Gln Leu Ser Asp Ser Gln Arg Thr Ser Thr Tyr
                 485                 490                 495

 Asp Asn Val Pro Ser Leu Pro Gly Ser Pro Gly Glu Glu Ala Ser
                 500                 505                 510

 Ala Leu Ser Ser Gln Ala Cys Asp Ser Lys Gly Asp Thr Leu Ala
                 515                 520                 525

 Ser Pro Asn Ser Glu Thr Gly Pro Gly Lys Lys Asn Ser Gly Glu
                 530                 535                 540

 Glu Glu Ile Asp Ser Leu Gln Arg Met Val Gln Glu Leu Arg Lys
                 545                 550                 555

 Glu Ile Glu Thr Gln Lys Gln Met Tyr Glu Glu Gln Ile Lys Asn
                 560                 565                 570

 Leu Glu Lys Glu Asn Tyr Asp Val Trp Ala Lys Val Val Arg Leu
                 575                 580                 585

 Asn Glu Glu Leu Glu Lys Glu Lys Lys Lys Ser Ala Ala Leu Glu
                 590                 595                 600

 Ile Ser Leu Arg Asn Met Glu Arg Ser Arg Glu Asp Val Glu Lys
                 605                 610                 615

 Arg Asn Lys Ala Leu Glu Glu Glu Val Lys Glu Phe Val Lys Ser
                 620                 625                 630

 Met Lys Glu Pro Lys Thr Glu Ala
                 635

<210> 19
<211> 2937
<212> DNA
<213> Homo sapien

<400> 19
 acgcgtccgc ttcggaatga gagactcaac cataatagaa agaatggaga 50

 actattaacc accattcttc agtgggctgt gattttcaga ggggaatact 100

 aagaaatggt tttccatact ggaacccaaa ggtaaagaca ctcaaggaca 150

 gacatttttg gcagagcata gatgaaaatg gcaagttccc tggctttcct 200

 tctgctcaac tttcatgtct ccctcttctt ggtccagctg ctcactcctt 250

 gctcagctca gttttctgtg cttggaccct ctgggcccat cctggccatg 300

 gtgggtgaag acgctgatct gccctgtcac ctgttcccga ccatgagtgc 350

 agagaccatg gagctgaggt gggtgagttc cagcctaagg caggtggtga 400

 acgtgtatgc agatggaaag gaagtggaag acaggcagag tgcaccatat 450

 cgagggagaa cttcgattct gcgggatggc atcactgcag ggaaggctgc 500

 tctccgaata cacaacgtca cagcctctga cagtggaaag tacttgtgtt 550

 atttccaaga tggtgacttc tacgaaaaag ccctggtgga gctgaaggtt 600

 gcagcattgg gttctgatct tcacattgaa gtgaagggtt atgaggatgg 650

 agggatccat ctggagtgca ggtccactgg ctggtacccc caaccccaaa 700

 taaagtggag cgacaccaag ggagagaaca tcccggctgt ggaagcacct 750

 gtggttgcag atggagtggg cctgtatgca gtagcagcat ctgtgatcat 800

 gagaggcagc tctggtgggg gtgtatcctg catcatcaga aattccctcc 850

 tcggcctgga aaagacagcc agcatatcca tcgcagaccc cttcttcagg 900

 agcgcccagc cctggatcgc ggccctggca gggaccctgc ctatctcgtt 950

 gctgcttctc gcaggagcca gttacttctt gtggagacaa cagaaggaaa 1000

 aaattgctct gtccagggag acagaaagag agcgagagat gaaagaaatg 1050

 ggatacgctg caacagagca agaaataagc ctaagagaga agctccagga 1100

 ggaactcaag tggaggaaaa tccagtacat ggctcgtgga gagaagtctt 1150

 tggcctatca tgaatggaaa atggccctct tcaaacctgc ggatgtgatt 1200

 ctggatccag acacggcaaa cgccatcctc cttgtttctg aggaccagag 1250

 gagtgtgcag cgtgctgaag agccgcggga tctgccagac aaccctgaga 1300

 gatttgaatg gcgttactgt gtccttggct gtgaaaactt cacatcaggg 1350

 agacattact gggaggtgga agtgggggac agaaaagagt ggcatattgg 1400

 ggtatgtagt aagaacgtgg agaggaaaaa aggttgggtc aaaatgacac 1450

 cggagaacgg atactggact atgggcctga ctgatgggaa taagtatcgg 1500

 gctctcactg agcccagaac caacctgaaa cttcctgagc ctcctaggaa 1550

 agtggggatc ttcctggact atgagactgg agagatctcg ttctataatg 1600

 ccacagatgg atctcatatc tacacctttc cgcacgcctc tttctctgag 1650

 cctctatatc ctgttttcag aattttgacc ttggagccca ctgccctgac 1700

 catttgccca ataccaaaag aagtagagag ttcccccgat cctgacctag 1750

 tgcctgatca ttccctggag acaccactga ccccgggctt agctaatgaa 1800

 agtggggagc ctcaggctga agtaacatct ctgcttctcc ctgcccaccc 1850

 tggagctgag gtctcccctt ctgcaacaac caatcagaac cataagctac 1900

 aggcacgcac tgaagcactt tactgatatt cattccatta ttccatatga 1950

 cagttgtttt gagtttcgta ccaccttatt gtccccttat acagataagg 2000

 aaactggggt gcagaaaggt gaattaactt tacaaagtag acatgacaag 2050

 tgaacagcag agctgggatc taaacagcaa taactaacat taacagagaa 2100

 tttaaaatgt tcttagtgct gtgttataag ctttggtgga tgtcactcct 2150

 ttaatcctca caacaccctg tcgggtagtc atattttgca agtatggaag 2200

 ctgaggcagg gcaacatgaa gtaacttaca taattcatac agtaatttgt 2250

 gcagttggga gatgttcagc cttagtccct ggctaattgc ctgttctttt 2300

 ccagcctgat tttttttccc acaggaagag cccacatgta gccctgaggt 2350

 ttccttccca ggacagctgc agggtagaga tcattttaag tgcttgtgga 2400

 gttgacatcc ctattgactc tttcccagct gatatcagag acttagaccc 2450

 agcactcctt ggattagctc tgcagagtgt cttggttgag agaataacct 2500

 catagtacca acatgacatg tgacttggaa agagactaga ggccacactt 2550

 gataaatcat ggggcacaga tatgttccca cccaacaaat gtgataagtg 2600

 attgtgcagc cagagccagc cttccttcaa tcaaggtttc caggcagagc 2650

 aaatacccta gagattctct gtgatatagg aaatttggat caaggaagct 2700

 aaaagaatta cagggatgtt tttaatccca ctatggactc agtctcctgg 2750

 aaataggtct gtccactcct ggtcattggt ggatgttaaa cccatattcc 2800

 tttcaactgc tgcctgctag ggaaaactgc tcctcattat catcactatt 2850

 attgctcacc actgtatccc ctctacttgg caagtggttg tcaagttcta 2900

 gttgttcaat aaatgtgtta ataatgaaaa aaaaaaa 2937

<210> 20
<211> 584
<212> PRT
<213> Homo sapien

<400> 20
 Met Lys Met Ala Ser Ser Leu Ala Phe Leu Leu Leu Asn Phe His
   1               5                  10                  15

 Val Ser Leu Phe Leu Val Gln Leu Leu Thr Pro Cys Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Arg Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asp Leu
                 140                 145                 150

 His Ile Glu Val Lys Gly Tyr Glu Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Lys Trp Ser
                 170                 175                 180

 Asp Thr Lys Gly Glu Asn Ile Pro Ala Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Ala Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Ser Ser Gly Gly Gly Val Ser Cys Ile Ile Arg Asn Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Pro Trp Ile Ala Ala Leu Ala Gly Thr
                 245                 250                 255

 Leu Pro Ile Ser Leu Leu Leu Leu Ala Gly Ala Ser Tyr Phe Leu
                 260                 265                 270

 Trp Arg Gln Gln Lys Glu Lys Ile Ala Leu Ser Arg Glu Thr Glu
                 275                 280                 285

 Arg Glu Arg Glu Met Lys Glu Met Gly Tyr Ala Ala Thr Glu Gln
                 290                 295                 300

 Glu Ile Ser Leu Arg Glu Lys Leu Gln Glu Glu Leu Lys Trp Arg
                 305                 310                 315

 Lys Ile Gln Tyr Met Ala Arg Gly Glu Lys Ser Leu Ala Tyr His
                 320                 325                 330

 Glu Trp Lys Met Ala Leu Phe Lys Pro Ala Asp Val Ile Leu Asp
                 335                 340                 345

 Pro Asp Thr Ala Asn Ala Ile Leu Leu Val Ser Glu Asp Gln Arg
                 350                 355                 360

 Ser Val Gln Arg Ala Glu Glu Pro Arg Asp Leu Pro Asp Asn Pro
                 365                 370                 375

 Glu Arg Phe Glu Trp Arg Tyr Cys Val Leu Gly Cys Glu Asn Phe
                 380                 385                 390

 Thr Ser Gly Arg His Tyr Trp Glu Val Glu Val Gly Asp Arg Lys
                 395                 400                 405

 Glu Trp His Ile Gly Val Cys Ser Lys Asn Val Glu Arg Lys Lys
                 410                 415                 420

 Gly Trp Val Lys Met Thr Pro Glu Asn Gly Tyr Trp Thr Met Gly
                 425                 430                 435

 Leu Thr Asp Gly Asn Lys Tyr Arg Ala Leu Thr Glu Pro Arg Thr
                 440                 445                 450

 Asn Leu Lys Leu Pro Glu Pro Pro Arg Lys Val Gly Ile Phe Leu
                 455                 460                 465

 Asp Tyr Glu Thr Gly Glu Ile Ser Phe Tyr Asn Ala Thr Asp Gly
                 470                 475                 480

 Ser His Ile Tyr Thr Phe Pro His Ala Ser Phe Ser Glu Pro Leu
                 485                 490                 495

 Tyr Pro Val Phe Arg Ile Leu Thr Leu Glu Pro Thr Ala Leu Thr
                 500                 505                 510

 Ile Cys Pro Ile Pro Lys Glu Val Glu Ser Ser Pro Asp Pro Asp
                 515                 520                 525

 Leu Val Pro Asp His Ser Leu Glu Thr Pro Leu Thr Pro Gly Leu
                 530                 535                 540

 Ala Asn Glu Ser Gly Glu Pro Gln Ala Glu Val Thr Ser Leu Leu
                 545                 550                 555

 Leu Pro Ala His Pro Gly Ala Glu Val Ser Pro Ser Ala Thr Thr
                 560                 565                 570

 Asn Gln Asn His Lys Leu Gln Ala Arg Thr Glu Ala Leu Tyr
                 575                 580

<210> 21
<211> 6060
<212> DNA
<213> Homo sapien

<400> 21
 atctcactga ggaccaacct ttcgacattc ttcagaaatc cttgcaagag 50

 gccaatatca ctgaacagac attggcagaa gaggcatatt tggatgccag 100

 tataggttca agccaacagt ttgcacaagc tcagcttcat ccttcttcat 150

 cagcatcctt tactcaggct tctaatgttt ctaattactc aggtcagacg 200

 ctgcagccta taggggtgac gcatgtgcct gttggagcat cgtttgcaag 250

 caatacagtg ggtgtacaac atggctttat gcaacatgtg gggatcagtg 300

 ttcccagcca gcatttgtct aatagcagtc agattagtgg ttctggtcaa 350

 atacagttaa ttgggtcatt tggtaatcat ccttccatga tgactattaa 400

 taacctagat ggatctcaaa tcatattaaa gggcagcggg cagcaagccc 450

 catcaaatgt gagtggaggg ctcctggttc atagacagac tcctaatggc 500

 aactccttgt ttgggaactc tagttccagt ccagtagcac agcctgttac 550

 cgttccattt aacagcacaa attttcaaac atctttacct gtgcataaca 600

 tcatcataca aaggggtctt gcaccaaatt caaataaagt cccaattaat 650

 atacagccaa agcctatcca gatgggtcag caaaatacat acaatgtgaa 700

 caatttggga attcagcagc accacgtaca acaagggatc tcttttgctt 750

 ctgcaagctc accccagggc tcagtagttg gtccacacat gtctgtgaac 800

 attgtaaacc aacagaacac aagaaagcca gtcacctcac aggcagtgag 850

 cagcactggg ggcagtattg ttattcattc ccccatgggc caacctcacg 900

 caccccaaag tcagttcctt atacctacaa gcctttctgt cagttccaac 950

 tcggtacacc acgtccagac tataaatggg caacttcttc aaactcaacc 1000

 ctctcagctc atttctggcc aagtggcctc agagcatgtc atgttgaaca 1050

 gaaactcttc caacatgctc aggaccaacc aaccatatac tggaccgatg 1100

 cttaacaacc agaatactgc tgtccactta gtgtctgggc agacatttgc 1150

 tgcctctgga agtccagtga tagccaatca tgcctctcct cagcttgtgg 1200

 gtggacagat gcccttgcag caggcatccc caactgtatt acacctgtca 1250

 cctgggcaga gcagcgtttc ccaaggaaga cctggcttcg ccaccatgcc 1300

 atcggtgaca agcatgtcag gacctagtcg gttccctgct gtcagctcag 1350

 ccagcactgc ccatcctagt cttgggtctg cagttcagtc tggttcatca 1400

 ggatcaaact ttacaggaga tcagctgacc cagccaaaca ggactccagt 1450

 accagtcagt gtgtctcatc gtcttccagt ttcttcttcc aagtctacca 1500

 gcaccttcag taacacacct ggaacaggaa cccagcaaca attcttctgc 1550

 caggctcaga aaaaatgtct gaatcagact tcccccattt ctgctcccaa 1600

 gaccacagac ggcctgaggc aagcacagat ccctgggctc ttgagcacca 1650

 cactgccagg gcaggattct ggaagcaaag ttatatccgc atccttagga 1700

 accgcacaac cacagcagga aaaagtagtt ggatcatctc ctggccatcc 1750

 agctgtgcag gtggagagtc attcgggagg acaaaaaagg cctgctgcga 1800

 aacagctaac gaaaggagct ttcattctcc agcagttgca gagggaccaa 1850

 gcccacactg tgacaccaga caaaagtcac ttccgatcac taagtgatgc 1900

 ggtacagaga ctgctctcct accacgtgtg ccagggctcc atgcccactg 1950

 aagaagactt gagaaaagtg gacaatgaat ttgagacagt tgccactcag 2000

 ctcctaaaaa ggacccaagc tatgcttaac aaatacagat gcctgctcct 2050

 agaagatgcc atgcgaatca atccctctgc tgagatggtg atgatcgata 2100

 ggatgttcaa ccaggaggaa agagcttccc tgtcccgaga caagcgtttg 2150

 gcacttgtag accctgaggg ttttcaggct gatttctgtt gttccttcaa 2200

 acttgataaa gctgctcatg agacacagtt tggccggagt gaccagcatg 2250

 gcagtaaagc aagcagctct ctgcaaccgc cagccaaggc ccaaggcaga 2300

 gaccgagcca aaaccggtgt gacggaaccc atgaatcatg accagtttca 2350

 tctagtgcct aatcacatcg tggtctctgc agaaggaaac atttctaaaa 2400

 aaacagaatg ccttggcaga gcactgaaat ttgacaaagt gggcttagtg 2450

 cagtaccaga gcacgtctga agagaaggcc agccggagag agcctctgaa 2500

 ggccagtcag tgctctcccg gccctgaggg gcaccggaaa acctcatcca 2550

 gatcggatca tggtactgag agcaaactgt caagcatcct agcagattcg 2600

 cacttggaga tgacgtgtaa caattccttc caggacaaaa gtctgaggaa 2650

 ttctccaaag aatgaagttt tacacacaga catcatgaaa gggtcaggcg 2700

 aaccccagcc agatctccag ctgacaaaga gcttggaaac cacatttaag 2750

 aacatcttgg aactcaaaaa ggcgggacgg cagccccaga gtgaccccac 2800

 ggttagcggc tctgttgagt tagatttccc caacttttct cctatggctt 2850

 cacaggaaaa ctgcctggaa aagttcatcc cggaccacag tgaaggtgtt 2900

 gtagaaactg actccatttt agaagcagct gtaaatagta tcctagagtg 2950

 ttaatagcag cagtcctccc cctaccccgc cccgagaccc caccccgaga 3000

 ccccaccccg gaccagttac attcgttcct ggcaaaagca aatggaaatg 3050

 gtctcctgtc tccagcctgc ttgatctttc atcacaggtt attctttcta 3100

 atctcaatcc tgttctttgt ttaagagcaa tacttgtcgt gattacaggg 3150

 agatccttta gtaaaattaa tccttggcag aaagcagtct gataggcccc 3200

 actcatttca agtgttatga aagtgcttat aggcattttg tttatttgtt 3250

 ttgtttttta aaaacactgt aactcaatga gaccacagta tacttggccc 3300

 ttggtaaaat tttgacaatc ataagtcatt tgaaaagaac agacttacta 3350

 aaatcaaacg agacggatag aagctacttt ttaaagaata tcccactgca 3400

 tctgcaaatt tagttttggg tttttttatt attattattt tgagtttttt 3450

 tgtgtgtgtt ttgttgttat tgttgagggg aagaccacat ggttcttccc 3500

 cctcagccat ctttgagcag taaattgctg gctgtgctgc cagggacccg 3550

 cagccctggt ggaaaagcca gtagcacata cgcagggcat tgcagggctt 3600

 ccctattgat ggttcaagtg cttttctgat gcttccggag caaaacctca 3650

 tgcttttagg catatctatg ttgaatttca cctagggaat gttctgttct 3700

 tagttacagc agcaaaattt gaaataattt caccaggcta aataaaggaa 3750

 aatggaaacc agttaagagg cacagtgtac agaggaggcc gggatagagc 3800

 catgagggtt ataatattaa tatgtatata tgtaaaagca tatatatgtt 3850

 aactattgag aaaaaacaag ttttgcattt tataattgga tatagtcaac 3900

 atataatgta tgtttttgtt tgttgctgga ttttgtttca tttaacctct 3950

 ctttgcaccc tctcccacaa caaataccaa gcatcaaaag cactttcatt 4000

 tgaaaattat tatgttgtaa tttttcagtt taaactttaa ggagactctg 4050

 gccttgttta tgcttcttgt ctgagaacag tagtgacccc tggcagcaat 4100

 tcattaccaa aacacagaca aaccaaaggt aaccagctag cccaccactg 4150

 aaaggaaaga tctgagacat gggattccca tttgagagcc aaaggatatg 4200

 ccctgtcatg gtttctgttt ggcctgtgtt catattagtg agcatggctt 4250

 actgcttttt tttttttttt tttttgtcag ggagtattct ccgttttcct 4300

 ttctcgtata cctgccccag gttatcccat ttctgttgtt acctttattc 4350

 ttaatgtcat tgtaaccatc acttatctcc tctcattggg aaagctacat 4400

 gatagtattt ttatgcactc ttctcccaca catacacaca cgtgcatgta 4450

 tctgagctgc tcggatccag aggtcatttt tgttacagtg tgtgcacact 4500

 cactctcctt cttagtgtgc atactctctc atttattctg tttatctccc 4550

 tggctctgga ggtgcagcca ctggtcttca ctttaatgtg ttgccagaat 4600

 ctgcttctgg ctgtcgccaa catggggatg acccccattg tcatcatgtt 4650

 gggcatttct tttccagatt ggcctgtgat ggaaaggaag gcttctaatt 4700

 agaaaacaca gcaacagaag acctataccc cggtgcccct gtgtcccact 4750

 acacacagaa aaccctgtga gatggccagt cttcataata gcaacgtacc 4800

 ttcaccccag ccacatgccc cagccaatac aaattggaaa atctggccca 4850

 ttttagggtt accatttttt ccttatttgt gccaatgtcc aagttgcaga 4900

 tttccccttt ttcctgtatt gtaacatatt agataagttg gtgtcgccag 4950

 ttggtacttt ctgtttgggt agtcctaggg taacaccctg ccctaaactc 5000

 catgatttca taggcttttc ttcccttggg gctcatgctc ccctaattcc 5050

 tagcaagatg atccttccta atcaaattct tctcattgca gaactttatc 5100

 cctggaagcc ttcatgtggg ctgctagtga gttacattaa ttactgcaaa 5150

 tcagtggaat tctcaagaga caagataagc ttcatgtaca tttgtcacct 5200

 ctctttcttc cctatcctgc cctgctgtcc caatcctagc ttttctatat 5250

 accatcttaa agggttttta agccctaaca cttgtctagc aaatggagag 5300

 cctaatttac caaaatgaaa cttgtaaatt tttgtgtcat tgtatgtaag 5350

 tttacttttt atggaggaag gattctagat aatgacaaat gaagattatg 5400

 acatgtattt cactcctgtg attaggttct acgcacatgg gtcataactc 5450

 gcatgtcgag ccccctctag tgaagggtag gagagctcag cctcggatgg 5500

 ccaacattca gttgttcagg ttcattcgtc aaagttaagt tttagaacta 5550

 tttgtactca gtaacaaaaa tcattttctt tttttttttt tttttctgtt 5600

 gtggaaaagc gtgaatttgt tattaagcat ttgattttct gtgtccttaa 5650

 gtacttcctg aagatgaagc aaaattttaa tctggcaatt atgaaaaaga 5700

 aatattttag ctctgaagga tttagtagat tctgttagat tagggaggcc 5750

 ttacagactg actttactta aagaggacgc gtcactcgct gtcagtgtgg 5800

 tgtgggcttt atttgcttaa ataccttcat ttgtatagta cgtctcactt 5850

 gaaattgctt tgtatacatt ttgtaaaaat atttataaaa tgttttgtaa 5900

 aaaaaaaaaa actataacaa attgcagttt attttgttat gttggataaa 5950

 tactgttaaa agaaaccagt cagtaactat attgttaatc catggttagg 6000

 aaatgtttag ttggagatta caaattgaaa caaccattgc aatacagcca 6050

 aagatttggg 6060

<210> 22
<211> 983
<212> PRT
<213> Homo sapien

<400> 22
 Leu Thr Glu Asp Gln Pro Phe Asp Ile Leu Gln Lys Ser Leu Gln
   1               5                  10                  15

 Glu Ala Asn Ile Thr Glu Gln Thr Leu Ala Glu Glu Ala Tyr Leu
                  20                  25                  30

 Asp Ala Ser Ile Gly Ser Ser Gln Gln Phe Ala Gln Ala Gln Leu
                  35                  40                  45

 His Pro Ser Ser Ser Ala Ser Phe Thr Gln Ala Ser Asn Val Ser
                  50                  55                  60

 Asn Tyr Ser Gly Gln Thr Leu Gln Pro Ile Gly Val Thr His Val
                  65                  70                  75

 Pro Val Gly Ala Ser Phe Ala Ser Asn Thr Val Gly Val Gln His
                  80                  85                  90

 Gly Phe Met Gln His Val Gly Ile Ser Val Pro Ser Gln His Leu
                  95                 100                 105

 Ser Asn Ser Ser Gln Ile Ser Gly Ser Gly Gln Ile Gln Leu Ile
                 110                 115                 120

 Gly Ser Phe Gly Asn His Pro Ser Met Met Thr Ile Asn Asn Leu
                 125                 130                 135

 Asp Gly Ser Gln Ile Ile Leu Lys Gly Ser Gly Gln Gln Ala Pro
                 140                 145                 150

 Ser Asn Val Ser Gly Gly Leu Leu Val His Arg Gln Thr Pro Asn
                 155                 160                 165

 Gly Asn Ser Leu Phe Gly Asn Ser Ser Ser Ser Pro Val Ala Gln
                 170                 175                 180

 Pro Val Thr Val Pro Phe Asn Ser Thr Asn Phe Gln Thr Ser Leu
                 185                 190                 195

 Pro Val His Asn Ile Ile Ile Gln Arg Gly Leu Ala Pro Asn Ser
                 200                 205                 210

 Asn Lys Val Pro Ile Asn Ile Gln Pro Lys Pro Ile Gln Met Gly
                 215                 220                 225

 Gln Gln Asn Thr Tyr Asn Val Asn Asn Leu Gly Ile Gln Gln His
                 230                 235                 240

 His Val Gln Gln Gly Ile Ser Phe Ala Ser Ala Ser Ser Pro Gln
                 245                 250                 255

 Gly Ser Val Val Gly Pro His Met Ser Val Asn Ile Val Asn Gln
                 260                 265                 270

 Gln Asn Thr Arg Lys Pro Val Thr Ser Gln Ala Val Ser Ser Thr
                 275                 280                 285

 Gly Gly Ser Ile Val Ile His Ser Pro Met Gly Gln Pro His Ala
                 290                 295                 300

 Pro Gln Ser Gln Phe Leu Ile Pro Thr Ser Leu Ser Val Ser Ser
                 305                 310                 315

 Asn Ser Val His His Val Gln Thr Ile Asn Gly Gln Leu Leu Gln
                 320                 325                 330

 Thr Gln Pro Ser Gln Leu Ile Ser Gly Gln Val Ala Ser Glu His
                 335                 340                 345

 Val Met Leu Asn Arg Asn Ser Ser Asn Met Leu Arg Thr Asn Gln
                 350                 355                 360

 Pro Tyr Thr Gly Pro Met Leu Asn Asn Gln Asn Thr Ala Val His
                 365                 370                 375

 Leu Val Ser Gly Gln Thr Phe Ala Ala Ser Gly Ser Pro Val Ile
                 380                 385                 390

 Ala Asn His Ala Ser Pro Gln Leu Val Gly Gly Gln Met Pro Leu
                 395                 400                 405

 Gln Gln Ala Ser Pro Thr Val Leu His Leu Ser Pro Gly Gln Ser
                 410                 415                 420

 Ser Val Ser Gln Gly Arg Pro Gly Phe Ala Thr Met Pro Ser Val
                 425                 430                 435

 Thr Ser Met Ser Gly Pro Ser Arg Phe Pro Ala Val Ser Ser Ala
                 440                 445                 450

 Ser Thr Ala His Pro Ser Leu Gly Ser Ala Val Gln Ser Gly Ser
                 455                 460                 465

 Ser Gly Ser Asn Phe Thr Gly Asp Gln Leu Thr Gln Pro Asn Arg
                 470                 475                 480

 Thr Pro Val Pro Val Ser Val Ser His Arg Leu Pro Val Ser Ser
                 485                 490                 495

 Ser Lys Ser Thr Ser Thr Phe Ser Asn Thr Pro Gly Thr Gly Thr
                 500                 505                 510

 Gln Gln Gln Phe Phe Cys Gln Ala Gln Lys Lys Cys Leu Asn Gln
                 515                 520                 525

 Thr Ser Pro Ile Ser Ala Pro Lys Thr Thr Asp Gly Leu Arg Gln
                 530                 535                 540

 Ala Gln Ile Pro Gly Leu Leu Ser Thr Thr Leu Pro Gly Gln Asp
                 545                 550                 555

 Ser Gly Ser Lys Val Ile Ser Ala Ser Leu Gly Thr Ala Gln Pro
                 560                 565                 570

 Gln Gln Glu Lys Val Val Gly Ser Ser Pro Gly His Pro Ala Val
                 575                 580                 585

 Gln Val Glu Ser His Ser Gly Gly Gln Lys Arg Pro Ala Ala Lys
                 590                 595                 600

 Gln Leu Thr Lys Gly Ala Phe Ile Leu Gln Gln Leu Gln Arg Asp
                 605                 610                 615

 Gln Ala His Thr Val Thr Pro Asp Lys Ser His Phe Arg Ser Leu
                 620                 625                 630

 Ser Asp Ala Val Gln Arg Leu Leu Ser Tyr His Val Cys Gln Gly
                 635                 640                 645

 Ser Met Pro Thr Glu Glu Asp Leu Arg Lys Val Asp Asn Glu Phe
                 650                 655                 660

 Glu Thr Val Ala Thr Gln Leu Leu Lys Arg Thr Gln Ala Met Leu
                 665                 670                 675

 Asn Lys Tyr Arg Cys Leu Leu Leu Glu Asp Ala Met Arg Ile Asn
                 680                 685                 690

 Pro Ser Ala Glu Met Val Met Ile Asp Arg Met Phe Asn Gln Glu
                 695                 700                 705

 Glu Arg Ala Ser Leu Ser Arg Asp Lys Arg Leu Ala Leu Val Asp
                 710                 715                 720

 Pro Glu Gly Phe Gln Ala Asp Phe Cys Cys Ser Phe Lys Leu Asp
                 725                 730                 735

 Lys Ala Ala His Glu Thr Gln Phe Gly Arg Ser Asp Gln His Gly
                 740                 745                 750

 Ser Lys Ala Ser Ser Ser Leu Gln Pro Pro Ala Lys Ala Gln Gly
                 755                 760                 765

 Arg Asp Arg Ala Lys Thr Gly Val Thr Glu Pro Met Asn His Asp
                 770                 775                 780

 Gln Phe His Leu Val Pro Asn His Ile Val Val Ser Ala Glu Gly
                 785                 790                 795

 Asn Ile Ser Lys Lys Thr Glu Cys Leu Gly Arg Ala Leu Lys Phe
                 800                 805                 810

 Asp Lys Val Gly Leu Val Gln Tyr Gln Ser Thr Ser Glu Glu Lys
                 815                 820                 825

 Ala Ser Arg Arg Glu Pro Leu Lys Ala Ser Gln Cys Ser Pro Gly
                 830                 835                 840

 Pro Glu Gly His Arg Lys Thr Ser Ser Arg Ser Asp His Gly Thr
                 845                 850                 855

 Glu Ser Lys Leu Ser Ser Ile Leu Ala Asp Ser His Leu Glu Met
                 860                 865                 870

 Thr Cys Asn Asn Ser Phe Gln Asp Lys Ser Leu Arg Asn Ser Pro
                 875                 880                 885

 Lys Asn Glu Val Leu His Thr Asp Ile Met Lys Gly Ser Gly Glu
                 890                 895                 900

 Pro Gln Pro Asp Leu Gln Leu Thr Lys Ser Leu Glu Thr Thr Phe
                 905                 910                 915

 Lys Asn Ile Leu Glu Leu Lys Lys Ala Gly Arg Gln Pro Gln Ser
                 920                 925                 930

 Asp Pro Thr Val Ser Gly Ser Val Glu Leu Asp Phe Pro Asn Phe
                 935                 940                 945

 Ser Pro Met Ala Ser Gln Glu Asn Cys Leu Glu Lys Phe Ile Pro
                 950                 955                 960

 Asp His Ser Glu Gly Val Val Glu Thr Asp Ser Ile Leu Glu Ala
                 965                 970                 975

 Ala Val Asn Ser Ile Leu Glu Cys
                 980

<210> 23
<211> 1835
<212> DNA
<213> Homo sapien

<400> 23
 ctcgctgcgc caccgcctcc cgccacccct gcccgcccga cagcgccgcc 50

 gcctgccccg ccatgggtcg acagaaggag ctggtgtccc gctgcgggga 100

 gatgctccac atccgctacc ggctgctccg acaggcgctg gccgagtgcc 150

 tggggaccct catcctggtg atgtttggct gtggctccgt ggcccaggtt 200

 gtgctcagcc ggggcaccca cggtggtttc ctcaccatca acctggcctt 250

 tggctttgct gtcactctgg gcatcctcat cgctggccag gtctctgggg 300

 cccacctgaa ccctgccgtg acctttgcca tgtgcttcct ggctcgtgag 350

 ccctggatca agctgcccat ctacaccctg gcacagacgc tgggagcctt 400

 cttgggtgct ggaatagttt ttgggctgta ttatgatgca atctggcact 450

 tcgccgacaa ccagcttttt gtttcgggcc ccaatggcac agccggcatc 500

 tttgctacct acccctctgg acacttggat atgatcaatg gcttctttga 550

 ccagttcata ggcacagcct cccttatcgt gtgtgtgctg gccattgttg 600

 acccctacaa caaccccgtc ccccgaggcc tggaggcctt caccgtgggc 650

 ctggtggtcc tggtcattgg cacctccatg ggcttcaact ccggctatgc 700

 cgtcaaccct gcccgggact ttggcccccg cctttttaca gcccttgcgg 750

 gctggggctc tgcagtcttc acgaccggcc agcattggtg gtgggtgccc 800

 atcgtgtccc cactcctggg ctccattgcg ggtgtcttcg tgtaccagct 850

 gatgatcggc tgccacctgg agcagccccc accctccaac gaggaagaga 900

 atgtgaagct ggcccatgtg aagcacaagg agcagatctg agtgggcagg 950

 ggccatctcc ccactccgct gccctggcct tgagcatcca ctgactgtcc 1000

 aagggccact cccaagaagc ccccttcacg atccaccctt tcaggctaag 1050

 gagctcccta tctaccctca ccccacgaga cagccccttc aggatttcca 1100

 ctggaccttg cccaaatagc accttaggcc actgccccta agctggggtg 1150

 gaaccggaat ttgggtcaat acatcctttt gtctcccaag ggaagagaat 1200

 gggcagcagg tatgtgtgtg tgtgcatgtg tgtgcatgtg tgtgcatgtg 1250

 tgtgcagggg tgtgtgtgtg tggggggggt tcccagatat tcagggcaag 1300

 ggaccagtcg gaagggattc tggctattgg gggagcccag agacagggga 1350

 aggcagcctg tccatctgtg cataaggaga ggaaagttcc agggtgtgta 1400

 tgtttcaggg gcttcacatg gaggagctgc agatagatat gtgtttctgt 1450

 gtatgtgtat gtctgccttt ttttctaagt gggggcttct acaggctttt 1500

 gggaagtagg gtggatgtgg gtagggctgg gaggaggggg ccacagctta 1550

 ggtttggagc tctggatgta catacataag taggagcagt gggacgtgtt 1600

 tctgtcataa tgcaggcatg aagggtggag tgaagtcagg tcataagttt 1650

 catgtttgct tttgttttgt tttgttttta atgtatgtag cagatgttac 1700

 agtcttaggg atccgggatg ggagacccca ctttagaaag ggtcgtcact 1750

 cctttaatcc tctactcaac aatgtactct tttactttta tattaaaaaa 1800

 aataaaataa atatgtgcct aaaaaaaaaa aaaaa 1835

<210> 24
<211> 292
<212> PRT
<213> Homo sapien

<400> 24
 Met Gly Arg Gln Lys Glu Leu Val Ser Arg Cys Gly Glu Met Leu
   1               5                  10                  15

 His Ile Arg Tyr Arg Leu Leu Arg Gln Ala Leu Ala Glu Cys Leu
                  20                  25                  30

 Gly Thr Leu Ile Leu Val Met Phe Gly Cys Gly Ser Val Ala Gln
                  35                  40                  45

 Val Val Leu Ser Arg Gly Thr His Gly Gly Phe Leu Thr Ile Asn
                  50                  55                  60

 Leu Ala Phe Gly Phe Ala Val Thr Leu Gly Ile Leu Ile Ala Gly
                  65                  70                  75

 Gln Val Ser Gly Ala His Leu Asn Pro Ala Val Thr Phe Ala Met
                  80                  85                  90

 Cys Phe Leu Ala Arg Glu Pro Trp Ile Lys Leu Pro Ile Tyr Thr
                  95                 100                 105

 Leu Ala Gln Thr Leu Gly Ala Phe Leu Gly Ala Gly Ile Val Phe
                 110                 115                 120

 Gly Leu Tyr Tyr Asp Ala Ile Trp His Phe Ala Asp Asn Gln Leu
                 125                 130                 135

 Phe Val Ser Gly Pro Asn Gly Thr Ala Gly Ile Phe Ala Thr Tyr
                 140                 145                 150

 Pro Ser Gly His Leu Asp Met Ile Asn Gly Phe Phe Asp Gln Phe
                 155                 160                 165

 Ile Gly Thr Ala Ser Leu Ile Val Cys Val Leu Ala Ile Val Asp
                 170                 175                 180

 Pro Tyr Asn Asn Pro Val Pro Arg Gly Leu Glu Ala Phe Thr Val
                 185                 190                 195

 Gly Leu Val Val Leu Val Ile Gly Thr Ser Met Gly Phe Asn Ser
                 200                 205                 210

 Gly Tyr Ala Val Asn Pro Ala Arg Asp Phe Gly Pro Arg Leu Phe
                 215                 220                 225

 Thr Ala Leu Ala Gly Trp Gly Ser Ala Val Phe Thr Thr Gly Gln
                 230                 235                 240

 His Trp Trp Trp Val Pro Ile Val Ser Pro Leu Leu Gly Ser Ile
                 245                 250                 255

 Ala Gly Val Phe Val Tyr Gln Leu Met Ile Gly Cys His Leu Glu
                 260                 265                 270

 Gln Pro Pro Pro Ser Asn Glu Glu Glu Asn Val Lys Leu Ala His
                 275                 280                 285

 Val Lys His Lys Glu Gln Ile
                 290

<210> 25
<211> 3351
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 713, 716
<223> Unknown base

<400> 25
 tttaggtaaa accggattta acccttggga aaaaaaaaaa aaaaggagag 50

 agaagacagt tcctttcctg tagaaattaa aacaaaatac aaattgagga 100

 agctctgcta cccaggctgt catggtagag aacttgaaga agacctgttt 150

 ggatggacac ctggtttcaa aagtcaggtg tggagactgt taaatgggag 200

 ggcctcatcc ataaatgatt tctggcaacg tcttcttcag gtggagcttg 250

 acgtcttttt aatgttactt ggggagggag tgctcattaa gggatgccag 300

 ggccagctct ggtggttcct ggggaggctg cgtccttccc tgcttctgca 350

 tgtcatgagg cagcaggaag gtttcccctg cacctgtctg tcctggctcc 400

 ctctgggtag ccccctactg ttctgtgctt cagcacagcc tggtttgtca 450

 agaggcacat agttggggct gggctgcatg gcacaggggc ttatgtgcct 500

 gctggttatt taattttcag ccttaagttt tctttaatat tttcctgttg 550

 gctatttaaa ggttttggtt atcttttatt ccttatctac aatcaagatg 600

 acaatgtaat tgaattatct tatttataac acggttcgtg attcatgatt 650

 catgattaca agtagaaaat atgtcatgtt cctcacctcc aaataaatat 700

 gtgtgtgtct gtntgngtgt ctatatgtat gtgcggagag ggagagagtg 750

 gggaaggaga gcagtgttat catacataga gaggctaaat gtgtcccatc 800

 cctcactgtc agctttataa aggagtttga ctccatccac agaagaatgt 850

 tttataagac taggaaaaca cgttgaaaac taggataaac agcaacaaaa 900

 atcaactaaa tatgttgtta ctgttgctaa ggattttctc cttagaataa 950

 tttaggattt ttaaaaattt ctgtttgcca aatgctgtag ataaatggcc 1000

 agattcttcc tatccctagg attcctttat tatttttttt cacagatttt 1050

 gagaacaagg gggagagata gtatggaaga ttaagattcc attaatctta 1100

 tagaactgtg ttgtcaccca aattcctgct tgtttgaaca tggcatcttc 1150

 atagattcag gattcactac cctctatagc tggatcttga aaattatctg 1200

 gccagataat tttgcatctg cttggatgat tgtagactga gatgtgagtg 1250

 gaggataaag tattagactt ttgctgagta actgccaacc aagaagtatt 1300

 tatcggacac ttactaggtg cctaggattg tatcagaggg aatatgaaat 1350

 gtgtccctgc cctacctagt tttaacgaca gaatatctat taaaggctac 1400

 ttagctgaag ggtaagggtg acaggtctag gggaagcttt gggaggtggt 1450

 gtgctgtgac agaaaaagtg gcagagtagg gacgagagac ctgcattcta 1500

 gccctgtttc tgtcacttgc tctgtacact tagacaacag cttgacctct 1550

 tgagctttag tttcctcctc tgcataatga gagggttaga ctactgaatt 1600

 gtatgggaaa aaaatacaaa ttcctgggtc ctaggccatg cctgctgaat 1650

 ccgactgttc aggaagaggc ctaggaaatc tgtgagggaa tccccagggg 1700

 aatctcgtga ccagccaggt gtgaaatctg ctaactggaa gatctcaaag 1750

 cttccttcac tttttgtgat tttgtggtca tgtaacgtta ctgtattatt 1800

 ctacgtaaat gtgggtactt ggatgtttat catactgttt ctctgtgttt 1850

 acatactaat ttgtgtaaga aatgcatttt agtctgtgta cctcaacctg 1900

 ctgtttgttt cctagaggtg ttagtagtct ttaaatacaa gtaagactta 1950

 agaggatatt tgatgttatt tacctggata ttttcttccc cttttattta 2000

 tttagaggaa attgagattc taggagccaa aaaaatgaaa acaaaattct 2050

 aaggcaaagt taaagaaaaa aattacatta tttcttacca tttgctactt 2100

 tataatgaaa atttaaaaat tatatgggaa gatttttctc tgggataaca 2150

 aatccttgtc ataaagtaag aggtcttttt aaagtaggta ggctataagg 2200

 cctgtaattt aaaataatac tcctttctct agggtttggt gcaattctcc 2250

 attaatgaag ataacatttg aattccccaa agcaggtgag gagtcgggga 2300

 ggagaaagcg atgttaaaat gaaaactcac tgcaaaagag gaggcagagg 2350

 aagaaggaat gtaaacccct taaagcagat gtgtgtgggg ccttatgaag 2400

 accaggattc tgcgggtgtc aggggattgc ccctcttgac agagactagg 2450

 gttttagact gaggcttcct gcagggtgtt cgcattgccc ttctccgttc 2500

 cccttcagac ctttctgggg agaagaggtg ggaggagggg agaaagactg 2550

 ttcatcttat tctgaatcct ggagcagctg aaggttttct cttgagtcag 2600

 gatgcagtgg taatgcatta accagcaagt gtggccaagg ataatgaaaa 2650

 agtgggaaag gaaggtcctc ctcctccctg attgtagcat ccagcagtct 2700

 ctgtagccag gttactcaag aaccacattt gatttcctgg ccctttgcct 2750

 tggcagtgat ggcattttta tttcactgtg ttttaaagtc ttcatttatt 2800

 tttataacat gggttaggga gaagggccac aaatggaggg attgtccttt 2850

 caagcaccac agcttcagat aaaattagta ctttcaaata ttgtccactt 2900

 taacttaaaa aattctagag ggattatatt ggagactcaa ctgcccttgg 2950

 ttttagttta taaaatggcc tagtactgtg gaattttaat tttagaaagt 3000

 cttagcatca gatcataaac attcattaaa agaactcaca tcccatctga 3050

 aacttcccag gggagttggg attcttagta gattggtaga aaggggctca 3100

 ttttctactg catttcccat ttttggtatc ttgttcagca tgttttattt 3150

 ttatttcttg tctgcagaac atcctatatt tatgagaaca ttctttaaga 3200

 agaccaccac atagaatacc ccttcctatc agctcgctct gatttagcct 3250

 taattttgtt aaatttttta gagatgaatg aagtgctgct gtggaaagaa 3300

 atgtacatat actatttctg tatcattaaa attacatttt tatggttcaa 3350

 g 3351

<210> 26
<211> 23
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 713, 716
<223> Unknown amino acid

<400> 26
 Leu Gly Lys Thr Gly Phe Asn Pro Trp Glu Lys Lys Lys Lys Arg
   1               5                  10                  15

 Arg Glu Lys Thr Val Pro Phe Leu
                  20

<210> 27
<211> 6113
<212> DNA
<213> Homo sapien

<400> 27
 ccccggtgca ccgtgctagc ccccagccag ggcgttgggg agggcggtgg 50

 ccatggccag tcacgtggac ctgctgacgg agctgcagct gctggagaag 100

 gtgcccacgc tggagcggct gcgggctgcc cagaagcgcc gggcccagca 150

 gctgaagaaa tgggcacagt acgagcagga cttgcagcac cgcaagcgaa 200

 agcatgagcg gaagcgcagc acgggcggtc gccgcaagaa agtgtccttc 250

 gaggccagcg tggccctgct ggaggcctcg ctgaggaacg acgccgagga 300

 agtacgctac ttcctgaaga ataaggtcag ccctgatttg tgcaatgagg 350

 acggactcac agccctacac cagtgctgca tcgacaactt tgaggaaatt 400

 gtgaagctgc tcctctccca tggtgccaat gtgaacgcca aggacaacga 450

 gctgtggaca cctctccatg ctgcagccac ctgcggccac atcaacctgg 500

 tgaagatcct cgttcagtat ggggccgact tgcttgctgt caactcggat 550

 gggaacatgc catatgacct ctgcgaggat gaacccaccc tggatgtcat 600

 cgagacctgc atggcatacc agggcatcac ccaagagaaa atcaacgaga 650

 tgcgggtggc tcctgagcag cagatgattg cggacatcca ctgcatgatc 700

 gcagcgggcc aggacctgga ctggatagat gcccagggtg ccacactgct 750

 gcacatagct ggagccaatg gatacctgcg ggcagctgag ctcctcctgg 800

 atcatggagt gcgtgtggat gtgaaggact gggatggctg ggagcccctg 850

 catgcagctg ccttctgggg acagatgcag atggcagagc tattggtgtc 900

 ccatggagct agtctcagtg caaggacatc catggatgag atgccaatag 950

 acctgtgcga ggaggaagag ttcaaggtcc tgctgctgga gctaaaacac 1000

 aagcatgatg tgatcatgaa gtcacagctg aggcacaagt catccttgag 1050

 ccggaggacc tccagcgcag gcagccgtgg gaaggtggtg cggcgagcca 1100

 gcctgtcgga caggaccaac ctgtatagga aggagtatga gggagaggcc 1150

 atcctgtggc agcggagtgc agctgaggat cagcggacct ccacctacaa 1200

 cggggacatc agggagacca ggacagacca agagaataag gaccctaacc 1250

 ccaggctgga gaagcccgtg ctactctccg aatttcctac caagatccca 1300

 cgaggtgaac tggacatgcc tgttgagaat ggcctccggg ctccggtcag 1350

 tgcctaccag tatgcgctgg ccaacgggga tgtctggaag gtgcatgagg 1400

 tgcctgacta cagcatggcc tatggcaacc ctggcgtggc cgacgccacc 1450

 ccgccctgga gcagctacaa ggaacagagc cctcagacgc ttctggagct 1500

 gaagcggcag cgggctgcag ccaagctgct cagccacccc ttccttagca 1550

 cacacctggg cagcagcatg gccaggacgg gcgagagtag cagtgaaggc 1600

 aaggctccct tgatcggagg cagaacttca ccgtacagca gcaatgggac 1650

 ctcggtatat tacacggtca ccagcggaga tcccccactc ttaaagttca 1700

 aggcccccat agaggagatg gaggagaagg tgcatggctg ttgccgtatc 1750

 tcctagtctc cgtgtgatgg aggagggaga tgcctgggga ggggctcctg 1800

 gaatccaggc cagcccaaca accctggctg gggaggtgtc agggcagctg 1850

 gggagaggtg ggctctgctt ttcagaggaa ctcagacccc agccctcagc 1900

 tggctgccca tagcatccca tgtcccacgt cccgtggttc tgcttcctgc 1950

 tgcatcgtct gccatctgac acaaggcctg tcgtggcctc ctggttcact 2000

 ctgctgtctg atcttgggag ggtgggcttg agatcccagc tctattcttg 2050

 gtataaaggc ttctccggat cagtacatgc atgtcacatt aacacacaca 2100

 cacacacaca tatacacaca cacacaagct cgatcagtgt gtgtaggaat 2150

 gacatacctg ggctcagggg aagcaagggg gcttagaatt tgtggggtat 2200

 tcccaaaagg atggaagtta agactcagag tctcattacc actgccaatg 2250

 tggttttagc aggggagggg acctgctaag ctgagaccca tagtcctgct 2300

 cagagttatc ccaaagtctg agccaccagc cacacctgac aggggtgaga 2350

 agtcctcgct gtgttcagag ggagccagga atctacatgg gtagatgaga 2400

 tagacacaga cctgctcccc gcagccttgt tgagagccac acttctgccc 2450

 atgccaggag ccagctgtgt gaccatccag gggtggaggg ggaaaaccag 2500

 gcaatttcgt tcctggaatc aaccaaatca tgttttcctc ttggatggaa 2550

 gtgtcaaagg cagaagggtg tgggaggggg acaaggtcag tatttaccaa 2600

 agtgtatctg attttaaaaa ttcctttagt ctgtaaaact cctagaggga 2650

 gggaggtaac tgaattcact tctttttgtg gatcgtatca aggtcactgg 2700

 gttttactgg ctggtgctgg gaaaatgaag ctaagtgagg agcttccatt 2750

 ggaatgcttt tccagggaga gaggccagtt aatttaaaaa aaacagtcgc 2800

 tagttaacag cgacagagcc cagcaccctg gggtctttgt gaatatccag 2850

 actgtttcag cccagcccat ctcagccaac cctccttaga ctgagctgtc 2900

 agagcaagca attaggggcc agcctgcctc cacctcccac ccccttccac 2950

 ctccatcagt catgtgtgca gagtcagtgc tcgggatccc gggcccagct 3000

 tttgcctttt tggggatgct tggtgagaca gatttgccag tcagcccttt 3050

 tgagttcccg cctcacccag gggctcccag cctgcacttg caggagtggt 3100

 gatgccccaa gtctgcgaat ccagggtgca cgtggtcaat atcccctcct 3150

 gcattcagga gagccatggt agggctggag ttgggtcttg cccagccctg 3200

 cagtttcata gtcccagcct tcctggtgct ggggagggag gactgtgaat 3250

 ggctgttctc ccctcactgc tgagtctccc aggaccccct ttggagatgc 3300

 ccatggcatg ggcactgccc acaggctcag ccagaacctc ttggtgtacc 3350

 cgataagctg caggttatcc cttgctctgt gcgcctttta tttgtcctta 3400

 aactacctcc ttagagctct gaaggggtct cctagttcca gattttaatt 3450

 tggggaacag atctgggttc tttttaaccc tcttctttct cagtctatga 3500

 gaaacttgcc ctgaggggca cctgggctag gggcttggga ctggaagacc 3550

 atccccgcct tgtgccacaa ctttggtcat gggatctgct ctttgtcatt 3600

 cttagccccc tactgtggcc cccatagccc cataacccag agagggagct 3650

 ggacttcagg gagcctgagt gatgctttcc caggagcagg gcagctggct 3700

 ggaccagaaa gtagagggcc catgggagtg actgcaccct tggtggctgc 3750

 tggaaaggga gaggttctca gcatcaggcc acctccaccc caatgccagg 3800

 atagatgtat tctagagtag gggtggaggc ggcccaggag gctgaagaca 3850

 ggtgcacaga tgcttcccac gaccttgcca tttggggtgg gctcttcaac 3900

 atctcaggct gtggctggaa caggacagga tgatctaaaa cacacgtacc 3950

 attggctgta aaacagtatg agcccagact gacgctgaaa tccctcatga 4000

 gccaacctta gctacaaggt agggagttct gagggaagcc gcgtgctcct 4050

 caggagagag ctgtttaggt tttccgatct ttttgctcag gggccaaaca 4100

 ctgaaggcac gtactgccca acccactgag cgcctgaggc cattccctcc 4150

 ttttccgcat gcctcctgcc tcctgggcta ttcctctcca cccagaaggc 4200

 tgggaatccc agctgattcc ctgacaggag ccgacttcac acacaggtga 4250

 ctctcaggca ttggctcatg ttttcagcca gggataaacc atcccttctt 4300

 ggggctttaa gtccctgggg agctttccct gtaggtctcc tgggtgttga 4350

 gagacaagtt ggagaccaac ctccaatgaa tgagccgcgg tcattcatta 4400

 attcactcac gtaatttact gagtagctgc aacatgccag cctctacgtt 4450

 aggttctgcg gataaaggag gaataagaca gagtcaggag aactgttcct 4500

 tgtggtttcc gtcccttggg gaccacaggc atcagcagtc ccattcaagt 4550

 cacctgaggc aaagtgtctg catcttcgtc cagcgaccct ttgcttttcg 4600

 gctcctagaa tccttagagt ctgaattcct ttagctggga acagctgtca 4650

 tggtcacccc tggataacat ttgccaccaa gtatagatgc tggatcttgg 4700

 gttccaggca gacatcatcc aggtccatct ggaactttca gtgatagctg 4750

 ccttcagcca gcatctttgg gggactctat aatagcagct tgagatcagt 4800

 gtctagaaga ctgttctgca atttgctgcc aaatgcatct caggttttta 4850

 aagtcattgt ttcttgctca tggtggctca tttattacat agtcccctca 4900

 ccccactaat ggataatggg aggaaaagtt gctgcttcct tcagcatcaa 4950

 agcctttcct tgggaatctg cctccctcca tggcaggggt ggattcggga 5000

 gctgggagta accaggcaaa gtcaaccaga tgcctagctc ctgctgagac 5050

 ccaggtccta tggcagctcc tcattagatt aaaggagacc acttccaaag 5100

 caggtgctgc atggctcacc atcatatgcc ccaaacaact gaaagttggc 5150

 ggttatcacc agactgtgag tttctggcaa gtagcttggg gaagctgaat 5200

 aaactctagg cccagggcta ctaaagactt caggatagaa ttctccatca 5250

 aatatacagc ataagtaaaa ctgctctgca ctgtttaatc catttccaag 5300

 gggcttagaa aagctaacaa gggtgtgtcc cctgtcctgc cccaccggtt 5350

 tgctggcttt gtaataacat aagaccattg tggttgttgg tgtcagatac 5400

 cttcccatcc tgagctctct cacctacctg ctctctctcc tagagcagga 5450

 tactggggta cttttaagaa gggtgctcct tttaagatgc ccagaaaagc 5500

 tgtatttaac tcttgctatt tgtaacttgg ggatggtctc ccctgcccca 5550

 gggcacataa gagcaaaggc tccaatggtc agtggatgac tctgcaaaag 5600

 tgaccccctg tgccagaagc tatagccctc tccccaacag gtctctcttg 5650

 ttggccagag ggcctgcttc ccatgggcat tgcaagtgcc accgtgcggg 5700

 gcctggctct gcacacccag gaaaagtctg cagaccccca gccctccgca 5750

 ataattcacc agaccagaag ccactggtgt acagagaaca cttaaaaaaa 5800

 tgtattttat gtgaaaaaaa attaaaactc tgtatactgt atcagcagct 5850

 ttgtgtaaaa atggcaatca agagagtcta atatatttaa aactttttta 5900

 aaaaaaatct tcgcggatct ttgatatcgt actgaggtaa cttccacgta 5950

 gccccttgcc acgcggcacc ggtgggcctt gggtccaaaa ctgtggctca 6000

 gccacatccc aaagggggca catgtccctg gagttgcttc cagctgccaa 6050

 ggcctgtgac agaattcgct gttaagagtt tttaattaaa attattaaat 6100

 tccttttaat aac 6113

<210> 28
<211> 567
<212> PRT
<213> Homo sapien

<400> 28
 Met Ala Ser His Val Asp Leu Leu Thr Glu Leu Gln Leu Leu Glu
   1               5                  10                  15

 Lys Val Pro Thr Leu Glu Arg Leu Arg Ala Ala Gln Lys Arg Arg
                  20                  25                  30

 Ala Gln Gln Leu Lys Lys Trp Ala Gln Tyr Glu Gln Asp Leu Gln
                  35                  40                  45

 His Arg Lys Arg Lys His Glu Arg Lys Arg Ser Thr Gly Gly Arg
                  50                  55                  60

 Arg Lys Lys Val Ser Phe Glu Ala Ser Val Ala Leu Leu Glu Ala
                  65                  70                  75

 Ser Leu Arg Asn Asp Ala Glu Glu Val Arg Tyr Phe Leu Lys Asn
                  80                  85                  90

 Lys Val Ser Pro Asp Leu Cys Asn Glu Asp Gly Leu Thr Ala Leu
                  95                 100                 105

 His Gln Cys Cys Ile Asp Asn Phe Glu Glu Ile Val Lys Leu Leu
                 110                 115                 120

 Leu Ser His Gly Ala Asn Val Asn Ala Lys Asp Asn Glu Leu Trp
                 125                 130                 135

 Thr Pro Leu His Ala Ala Ala Thr Cys Gly His Ile Asn Leu Val
                 140                 145                 150

 Lys Ile Leu Val Gln Tyr Gly Ala Asp Leu Leu Ala Val Asn Ser
                 155                 160                 165

 Asp Gly Asn Met Pro Tyr Asp Leu Cys Glu Asp Glu Pro Thr Leu
                 170                 175                 180

 Asp Val Ile Glu Thr Cys Met Ala Tyr Gln Gly Ile Thr Gln Glu
                 185                 190                 195

 Lys Ile Asn Glu Met Arg Val Ala Pro Glu Gln Gln Met Ile Ala
                 200                 205                 210

 Asp Ile His Cys Met Ile Ala Ala Gly Gln Asp Leu Asp Trp Ile
                 215                 220                 225

 Asp Ala Gln Gly Ala Thr Leu Leu His Ile Ala Gly Ala Asn Gly
                 230                 235                 240

 Tyr Leu Arg Ala Ala Glu Leu Leu Leu Asp His Gly Val Arg Val
                 245                 250                 255

 Asp Val Lys Asp Trp Asp Gly Trp Glu Pro Leu His Ala Ala Ala
                 260                 265                 270

 Phe Trp Gly Gln Met Gln Met Ala Glu Leu Leu Val Ser His Gly
                 275                 280                 285

 Ala Ser Leu Ser Ala Arg Thr Ser Met Asp Glu Met Pro Ile Asp
                 290                 295                 300

 Leu Cys Glu Glu Glu Glu Phe Lys Val Leu Leu Leu Glu Leu Lys
                 305                 310                 315

 His Lys His Asp Val Ile Met Lys Ser Gln Leu Arg His Lys Ser
                 320                 325                 330

 Ser Leu Ser Arg Arg Thr Ser Ser Ala Gly Ser Arg Gly Lys Val
                 335                 340                 345

 Val Arg Arg Ala Ser Leu Ser Asp Arg Thr Asn Leu Tyr Arg Lys
                 350                 355                 360

 Glu Tyr Glu Gly Glu Ala Ile Leu Trp Gln Arg Ser Ala Ala Glu
                 365                 370                 375

 Asp Gln Arg Thr Ser Thr Tyr Asn Gly Asp Ile Arg Glu Thr Arg
                 380                 385                 390

 Thr Asp Gln Glu Asn Lys Asp Pro Asn Pro Arg Leu Glu Lys Pro
                 395                 400                 405

 Val Leu Leu Ser Glu Phe Pro Thr Lys Ile Pro Arg Gly Glu Leu
                 410                 415                 420

 Asp Met Pro Val Glu Asn Gly Leu Arg Ala Pro Val Ser Ala Tyr
                 425                 430                 435

 Gln Tyr Ala Leu Ala Asn Gly Asp Val Trp Lys Val His Glu Val
                 440                 445                 450

 Pro Asp Tyr Ser Met Ala Tyr Gly Asn Pro Gly Val Ala Asp Ala
                 455                 460                 465

 Thr Pro Pro Trp Ser Ser Tyr Lys Glu Gln Ser Pro Gln Thr Leu
                 470                 475                 480

 Leu Glu Leu Lys Arg Gln Arg Ala Ala Ala Lys Leu Leu Ser His
                 485                 490                 495

 Pro Phe Leu Ser Thr His Leu Gly Ser Ser Met Ala Arg Thr Gly
                 500                 505                 510

 Glu Ser Ser Ser Glu Gly Lys Ala Pro Leu Ile Gly Gly Arg Thr
                 515                 520                 525

 Ser Pro Tyr Ser Ser Asn Gly Thr Ser Val Tyr Tyr Thr Val Thr
                 530                 535                 540

 Ser Gly Asp Pro Pro Leu Leu Lys Phe Lys Ala Pro Ile Glu Glu
                 545                 550                 555

 Met Glu Glu Lys Val His Gly Cys Cys Arg Ile Ser
                 560                 565

<210> 29
<211> 2121
<212> DNA
<213> Homo sapien

<400> 29
 ggcacgaggg cccggcggca ggtcccagcc cggggctaga gaccgagggc 50

 cggggtccgg gcccggcggc gggacccagg cggttgaggc tggtcaggag 100

 tcagccagcc tgaaagagca ggatggatct tgatgtggtt aacatgtttg 150

 tgattgcggg cggcacgctg gccatcccaa tcctggcatt tgtggcttca 200

 tttcttctgt ggccttcagc actgataaga atctattatt ggtactggcg 250

 gaggacattg ggcatgcaag tccgctatgt tcaccatgaa gactatcagt 300

 tctgttattc cttccggggc aggcctgggc acaaaccctc catcctcatg 350

 ctccacggat tctctgccca caaggatatg tggctcagtg tggtcaagtt 400

 ccttccaaag aacctgcact tggtctgcgt ggacatgcca ggacatgagg 450

 gcaccacccg ctcctccctg gatgacctgt ccatagatgg gcaagttaag 500

 aggatacacc agtttgtaga atgcctgaag ctgaacaaaa aacctttcca 550

 cctggtaggc acctccatgg gtggccaggt ggctggggtg tatgctgctt 600

 actacccatc ggatgtctcc agcctgtgtc tcgtgtgtcc tgctggcctg 650

 cagtactcaa ctgacaatca atttgtacaa cggctcaaag aactgcaggg 700

 ctctgccgcc gtggagaaga ttcccttgat cccgtctacc ccagaagaga 750

 tgagtgaaat gcttcagctc tgctcctatg tccgcttcaa ggtgccccag 800

 cagatcctgc aaggccttgt cgatgtccgc atccctcata acaacttcta 850

 ccgaaagttg tttttggaaa tcgtcagtga gaagtccaga tactctctcc 900

 atcagaacat ggacaagatc aaggttccga cgcagatcat ctgggggaaa 950

 caagaccagg tgctggatgt gtctggggca gacatgttgg ccaagtcaat 1000

 tgccaactgc caggtggagc ttctggaaaa ctgtgggcac tcagtagtga 1050

 tggaaagacc caggaagaca gccaagctca taatcgactt tttagcttct 1100

 gtgcacaaca cagacaacaa caagaagctg gactgaggcc ccgactgcag 1150

 cctgcattct gcacacagca tctgctccca tcccccaagt ctgacgcagc 1200

 caccactctc agggatcctg ccccaaatgc ggtcggagcg ccagtgaccc 1250

 tgaggaagcc cgtcccttat ccctggtatc cacggttccc cagagctttg 1300

 gggaccacgc gaaaacctcc aagatatttt tcacaaaata gaaactcata 1350

 tggaacaaaa taagaaaccc cagccatgaa atctaccatg aagtcttcaa 1400

 gttcatgtca ctgagaagct tgtgcaaagc agccaccttg gaccataatt 1450

 aaatcaagga cattttcttt gagacattcc ttatagttgg agactcaaga 1500

 tatttttgtt gcatcaggtg tattcccttg catgggcagt ggcttttata 1550

 ggagcattag tcctcattcg ctgaaccctg ttgtttaggt ctaatttaag 1600

 ttttacatag agacccatgt atgactgcag cccattggct gcaagaccag 1650

 ggaggaaagt ggcaagctgt agaaaatgtt tacacgcatg gaggggcatt 1700

 gctctagccc tcagagcgtc cggagcagca gggtacatgg gtgggaggtt 1750

 cattcagcac ccaccagtca ggtatgttct gagtgaaccc acagcagtcg 1800

 cagaatgagc acctggcagg gtgggtttcc taggaataat ttattatttt 1850

 taaaaatagg cctaataaag caataatgtt ctagacatct gtctaagtaa 1900

 tcagactcag gttccacaca caagcaacaa ctcgtgggcc tcttttctat 1950

 ttcaatgtgc tactaagaac ccttggatgt aacatactag ttagttaatg 2000

 aattctgtga attctgtgaa gagtaatgtg attgaaaata agtctaaaca 2050

 gctgtaaaag tgaccacaat gacatgaaat aaatttaata agtctagatc 2100

 agcaaaaaaa aaaaaaaaaa a 2121

<210> 30
<211> 337
<212> PRT
<213> Homo sapien

<400> 30
 Met Asp Leu Asp Val Val Asn Met Phe Val Ile Ala Gly Gly Thr
   1               5                  10                  15

 Leu Ala Ile Pro Ile Leu Ala Phe Val Ala Ser Phe Leu Leu Trp
                  20                  25                  30

 Pro Ser Ala Leu Ile Arg Ile Tyr Tyr Trp Tyr Trp Arg Arg Thr
                  35                  40                  45

 Leu Gly Met Gln Val Arg Tyr Val His His Glu Asp Tyr Gln Phe
                  50                  55                  60

 Cys Tyr Ser Phe Arg Gly Arg Pro Gly His Lys Pro Ser Ile Leu
                  65                  70                  75

 Met Leu His Gly Phe Ser Ala His Lys Asp Met Trp Leu Ser Val
                  80                  85                  90

 Val Lys Phe Leu Pro Lys Asn Leu His Leu Val Cys Val Asp Met
                  95                 100                 105

 Pro Gly His Glu Gly Thr Thr Arg Ser Ser Leu Asp Asp Leu Ser
                 110                 115                 120

 Ile Asp Gly Gln Val Lys Arg Ile His Gln Phe Val Glu Cys Leu
                 125                 130                 135

 Lys Leu Asn Lys Lys Pro Phe His Leu Val Gly Thr Ser Met Gly
                 140                 145                 150

 Gly Gln Val Ala Gly Val Tyr Ala Ala Tyr Tyr Pro Ser Asp Val
                 155                 160                 165

 Ser Ser Leu Cys Leu Val Cys Pro Ala Gly Leu Gln Tyr Ser Thr
                 170                 175                 180

 Asp Asn Gln Phe Val Gln Arg Leu Lys Glu Leu Gln Gly Ser Ala
                 185                 190                 195

 Ala Val Glu Lys Ile Pro Leu Ile Pro Ser Thr Pro Glu Glu Met
                 200                 205                 210

 Ser Glu Met Leu Gln Leu Cys Ser Tyr Val Arg Phe Lys Val Pro
                 215                 220                 225

 Gln Gln Ile Leu Gln Gly Leu Val Asp Val Arg Ile Pro His Asn
                 230                 235                 240

 Asn Phe Tyr Arg Lys Leu Phe Leu Glu Ile Val Ser Glu Lys Ser
                 245                 250                 255

 Arg Tyr Ser Leu His Gln Asn Met Asp Lys Ile Lys Val Pro Thr
                 260                 265                 270

 Gln Ile Ile Trp Gly Lys Gln Asp Gln Val Leu Asp Val Ser Gly
                 275                 280                 285

 Ala Asp Met Leu Ala Lys Ser Ile Ala Asn Cys Gln Val Glu Leu
                 290                 295                 300

 Leu Glu Asn Cys Gly His Ser Val Val Met Glu Arg Pro Arg Lys
                 305                 310                 315

 Thr Ala Lys Leu Ile Ile Asp Phe Leu Ala Ser Val His Asn Thr
                 320                 325                 330

 Asp Asn Asn Lys Lys Leu Asp
                 335

<210> 31
<211> 1853
<212> DNA
<213> Homo sapien

<400> 31
 ctgagcctct ccgtgcaatg attaacccgg cggggcggcc ggcgcgggac 50

 ccgagacgga ggcgcggggc cggggcggga ccccgcagga ccgctcggct 100

 tcctgctctc gccggagttt ccgcgtagag ggcgcatcgc cggcccgggg 150

 cccttggtgc ggcgtggcgc agggcgcggc gtggggcgcg cgtgggcgcg 200

 gcgcaggcgg cccgggtcac catgaggact ctccgcaggt tgaagttcat 250

 gagttcgccc agcctcagtg acctgggcaa gagagagccg gccgccgccg 300

 cggacgagcg gggcacgcag cagcgccggg cctgcgccaa cgccacctgg 350

 aacagcatcc acaacggggt gatcgccgtc ttccagcgca aggggctgcc 400

 cgaccaggag ctcttcagcc tcaacgaggg cgtccggcag ctgttgaaga 450

 cagagctggg gtccttcttc acggagtacc tgcagaacca gctgctgaca 500

 aaaggcatgg tgatccttcg ggacaagatt cgcttctatg agggacagaa 550

 gctgctggac tcactggcag agacctggga cttcttcttc agtgacgtgc 600

 tgcccatgct gcaggccatc ttctacccgg tgcagggcaa ggagccatcg 650

 gtgcgccagc tggccctgct gcacttccgg aatgccatca ccctcagtgt 700

 gaagctagag gatgcgctgg cccgggccca tgcccgtgtg ccccctgcca 750

 tcgtgcagat gctgctggtg ctgcaggggg tacatgagtc caggggcgtg 800

 actgaggact acctgcgcct ggagacgctg gtccagaagg tggtgtcgcc 850

 atacctgggc acctacggcc tccactccag cgaggggccc ttcacccatt 900

 cctgcatcct ggaaaagcgc ctcctccgcc gctcccgctc gggggacgtg 950

 ctggccaaga accctgtggt gcgctccaag agctacaaca cgcctctgct 1000

 gaaccccgtg caggagcacg aggcggaggg cgcggcggcc ggcggtacca 1050

 gcatccgcag gcactctgtg tcggagatga cgtcctgccc cgagcctcag 1100

 ggcttctccg acccgcccgg ccagggcccc accgggacct tcaggtcctc 1150

 cccggcgccc cactcagggc cctgccccag cagactgtac cccacgaccc 1200

 agccccctga gcagggcttg gatcccaccc gcagctccct gccccgctcc 1250

 agcccggaga acctggtgga ccagatcctg gagtccgtgg actcggattc 1300

 tgaagggatt ttcattgact ttggccgggg ccggggctct ggcatgtccg 1350

 acttggaggg ctctgggggc cggcagagtg tcgtgtgagg cctcacagct 1400

 ggccttgagt ttttactgac acgtccctgt gtgcgggggt gtccatgtgg 1450

 cgtgtgtgtg agtgagactt ttttactgcg tcccgtcccg ccagccctat 1500

 cggcctcgtc actggccttg gtcactttgt atttctgtct tggttggaaa 1550

 taccatcagc cttccttgct cggcccaggt ctgtttcagg catctgagtc 1600

 ggcgtttacc caggggccgg gccagagacg ggggtcggcc gctcgctccc 1650

 acgctcctcc tgccccagcc ctctggtgtc cacacctgcc cacagagaat 1700

 gtaaacccag tgggctctgc ccacgccggg ccccaaagtg accagactcc 1750

 agcacacctg tctcctcctg cctggggtgg ccatggggat ggaagggggt 1800

 ggaataaaac ctgtcaccct gggaaaaaaa aaaaaaaaaa aaaaaaaaaa 1850

 aaa 1853

<210> 32
<211> 388
<212> PRT
<213> Homo sapien

<400> 32
 Met Arg Thr Leu Arg Arg Leu Lys Phe Met Ser Ser Pro Ser Leu
   1               5                  10                  15

 Ser Asp Leu Gly Lys Arg Glu Pro Ala Ala Ala Ala Asp Glu Arg
                  20                  25                  30

 Gly Thr Gln Gln Arg Arg Ala Cys Ala Asn Ala Thr Trp Asn Ser
                  35                  40                  45

 Ile His Asn Gly Val Ile Ala Val Phe Gln Arg Lys Gly Leu Pro
                  50                  55                  60

 Asp Gln Glu Leu Phe Ser Leu Asn Glu Gly Val Arg Gln Leu Leu
                  65                  70                  75

 Lys Thr Glu Leu Gly Ser Phe Phe Thr Glu Tyr Leu Gln Asn Gln
                  80                  85                  90

 Leu Leu Thr Lys Gly Met Val Ile Leu Arg Asp Lys Ile Arg Phe
                  95                 100                 105

 Tyr Glu Gly Gln Lys Leu Leu Asp Ser Leu Ala Glu Thr Trp Asp
                 110                 115                 120

 Phe Phe Phe Ser Asp Val Leu Pro Met Leu Gln Ala Ile Phe Tyr
                 125                 130                 135

 Pro Val Gln Gly Lys Glu Pro Ser Val Arg Gln Leu Ala Leu Leu
                 140                 145                 150

 His Phe Arg Asn Ala Ile Thr Leu Ser Val Lys Leu Glu Asp Ala
                 155                 160                 165

 Leu Ala Arg Ala His Ala Arg Val Pro Pro Ala Ile Val Gln Met
                 170                 175                 180

 Leu Leu Val Leu Gln Gly Val His Glu Ser Arg Gly Val Thr Glu
                 185                 190                 195

 Asp Tyr Leu Arg Leu Glu Thr Leu Val Gln Lys Val Val Ser Pro
                 200                 205                 210

 Tyr Leu Gly Thr Tyr Gly Leu His Ser Ser Glu Gly Pro Phe Thr
                 215                 220                 225

 His Ser Cys Ile Leu Glu Lys Arg Leu Leu Arg Arg Ser Arg Ser
                 230                 235                 240

 Gly Asp Val Leu Ala Lys Asn Pro Val Val Arg Ser Lys Ser Tyr
                 245                 250                 255

 Asn Thr Pro Leu Leu Asn Pro Val Gln Glu His Glu Ala Glu Gly
                 260                 265                 270

 Ala Ala Ala Gly Gly Thr Ser Ile Arg Arg His Ser Val Ser Glu
                 275                 280                 285

 Met Thr Ser Cys Pro Glu Pro Gln Gly Phe Ser Asp Pro Pro Gly
                 290                 295                 300

 Gln Gly Pro Thr Gly Thr Phe Arg Ser Ser Pro Ala Pro His Ser
                 305                 310                 315

 Gly Pro Cys Pro Ser Arg Leu Tyr Pro Thr Thr Gln Pro Pro Glu
                 320                 325                 330

 Gln Gly Leu Asp Pro Thr Arg Ser Ser Leu Pro Arg Ser Ser Pro
                 335                 340                 345

 Glu Asn Leu Val Asp Gln Ile Leu Glu Ser Val Asp Ser Asp Ser
                 350                 355                 360

 Glu Gly Ile Phe Ile Asp Phe Gly Arg Gly Arg Gly Ser Gly Met
                 365                 370                 375

 Ser Asp Leu Glu Gly Ser Gly Gly Arg Gln Ser Val Val
                 380                 385

<210> 33
<211> 5492
<212> DNA
<213> Homo sapien

<400> 33
 tgagggcttt gctatgacct cagtcccctc acggagccac gactgcccct 50

 tgctgccaca gcctttccaa gaccctgccc ggccctgccc catcctcagc 100

 cccgagtcac catgggcagc gtcagtagcc tcatctccgg ccacagcttc 150

 cacagcaagc actgccgggc ttcgcagtac aagctgcgca agtcctccca 200

 cctcaagaag ctcaaccggt attccgacgg gctgctgagg tttggcttct 250

 cccaggactc cggtcacggc aagtccagct ccaaaatggg caagagcgaa 300

 gacttcttct acatcaaggt cagccagaaa gcccggggct cccatcaccc 350

 agattacacg gcactgtcca gcggggattt agggggccag gctggggtgg 400

 actttgaccc gtccacaccc cccaagctca tgcccttctc caatcagcta 450

 gaaatgggct ccgagaaggg tgcagtgagg cccacagcct tcaagcctgt 500

 gctgccacgg tcaggagcca tcctgcactc ctccccggag agtgccagcc 550

 accagctgca ccccgcccct ccagacaagc ccaaggagca ggagctgaag 600

 cctggcctgt gctctggggc gctgtcagac tccggccgga actccatgtc 650

 cagcctgccc acacacagca ccagcagcag ctaccagctg gacccgctgg 700

 tcacacccgt gggacccaca agccgttttg ggggctccgc ccacaacatc 750

 acccagggca tcgtcctcca ggacagcaac atgatgagcc tgaaggctct 800

 gtccttctcc gacggaggta gcaagctggg ccactcgaac aaggcagaca 850

 agggcccctc gtgtgtccgc tcccccatct ccacggacga gtgcagcatc 900

 caggagctgg agcagaagct gttggagagg gagggcgccc tccagaagct 950

 gcagcgcagc tttgaggaga aggagcttgc ctccagcctg gcctacgagg 1000

 agcggccgcg gcgctgcagg gacgagctgg agggcccgga gcccaaaggc 1050

 ggcaacaagc tcaagcaggc ctcgcagaag agccagcgcg cgcagcaggt 1100

 cctgcacctg caggtactgc agcttcagca ggagaagcgg cagctccggc 1150

 aggagctcga gagcctcatg aaggagcagg acctgctgga gaccaagctc 1200

 aggtcctacg agagggagaa gaccagcttc ggccccgcgc tggaggagac 1250

 ccagtgggag gtgtgccaga agtcaggcga gatctccctc ctgaagcagc 1300

 agctgaagga gtcccagacg gaggtgaacg ccaaggctag cgagatcctg 1350

 ggtctcaagg cacagctgaa ggacacgcgg ggcaagctgg agggcctgga 1400

 gctgaggacc caggacctgg agggcgccct gcgcaccaag ggcctggagc 1450

 tggaggtctg tgagaatgag ctgcagcgca agaagaacga ggcggagctg 1500

 ctgcgggaga aggtgaacct gctggagcag gagctgcagg agctgcgggc 1550

 ccaggccgcc ctggcccgcg acatggggcc gcccaccttc cccgaggacg 1600

 tccctgccct gcagcgggag ctggagcggc tgcgggccga gctgcgggag 1650

 gagcggcaag gccatgacca gatgtcctcg ggcttccagc atgagcggct 1700

 cgtgtggaag gaggagaagg agaaggtgat tcagtaccag aaacagctgc 1750

 agcagagcta cgtggccatg taccagcgga accagcgcct ggagaaggcc 1800

 ctgcagcagc tggcacgtgg ggacagcgcc ggggagccct tggaggttga 1850

 cctggaaggg gctgacatcc cctacgagga catcatagcc actgagatct 1900

 gaggggctgc ctgggaaggc gagtctgggg acctggcact gggaggcagg 1950

 gctctcccgt gcatcccccc tgctcagcaa ttcagacccc tctgagagac 2000

 gccactccct gggacacaga cccaggaccc ccgaggggag ggcaggatgg 2050

 cctttccttc cctctctgat gtcccagtgc tcaccagccc tgcagcccac 2100

 cagacgtcag gccctgactc ctctggcttt cccaggagat gggtccaggg 2150

 gtctgtctgc tttggttaag ggctccctaa actttggcct ttgttcgaaa 2200

 tagatatcct ctccccctcc tccagggaag gtggccacag caagaacagc 2250

 ggctcccctc cgcttctcat cccaacctct ttttcctcct ggacacattg 2300

 gaatgccttg gaaatagaaa gaagccatat atgaccagaa gccttggaac 2350

 cagccccatc agaacctgag ctattttcct ctggccgcag aggtgtaggg 2400

 gtggaatgag ccgcggggaa gctggctttg aaacctcagg gctgtcccag 2450

 ccccggcaag ccacaggaag gaggggagag acaggcagcc cagcagtgtg 2500

 gagaccctgc cacagccaga ggagggcaga gggagaatcc aagggttgag 2550

 agccagtggc gggtgatggc cagcccctgg ggcccagccc ctgtttactg 2600

 gttcttgcaa atgggagctg agcagcctct ggacagccag tgacctttga 2650

 cctcggtgac cactcttctt taagccatag accctgaggc cctgggctgg 2700

 gtgctgggaa gggagggttg aaaccaccgt gaaccagagg gtgtggcttt 2750

 ccaggcaccc tcagggagcc tccccatctg tccagctggg gccagaggct 2800

 gggagtccct acctgcttca cgttggccgg cggctactct ggaatgtttt 2850

 tccctcccca gaatcaagct tttgcttgat ccagaagagc ccatatcact 2900

 aagatggcat atatgtgatc tgggcatttt cctcctctgc ctacagccag 2950

 gtttagcggc aaacctttcc cccttagcac cttcagggct gagttctggg 3000

 tttctagagg tcaggacggc tcctcagagc gccaggaagc cagagcccca 3050

 agcaggacga aaaagaggca tacacacagc agtgtgaata gcctggccac 3100

 cagccatcct ccctccacct caagaccccc atttgtccca gactaaagga 3150

 tccagagagc agctcccttt ctcaggagct tgggcagtgc cccagggagt 3200

 ccagggtttc tctgcagatg tgcggagcgg gaggcggtgg tagagagaga 3250

 taaaaggtgg agtttctctg ttgtttggtt cagggatttt atttttaatt 3300

 ttatgagaca gggtcttgct ctgtccccca ggctggagtg cagtggcatg 3350

 atcatagctc actgcagcct catactcctg ggctcaagca atcctcctgc 3400

 ctcagccttc caactagctg ggactacagg tgcgcgccac cgtgcctggc 3450

 taacttttca ttttttttgt agggacgggg tctcgttttg ttgccaaagc 3500

 tggtctcaaa cttgtggcct caagcaatcc acctgccttg gcctcccaaa 3550

 gtgctgagat tgcagatgtg agccaccgtg cctggccaga tttttctttt 3600

 attcttcttt ctttttcttt tttgctttct tgtcttttca gaagcaagcc 3650

 agacctagca ggctgttcca tgttctattt ttgactgtag ccacagctgc 3700

 tgttctcagg acagcatccc ttcccacatg cctgcgcctg ctgcctgctg 3750

 agatgaggag gggagcgtct gggaacttgc gagtccaagg ccagtcccca 3800

 tttctgcctc gctcaccgct ggcccttaga gaccccgagg taggggtggg 3850

 gagatgcttc tctccttgcc ccccgccctc atgggtccta gcccttccct 3900

 gagtgcgggc tgaggccaga gtcacctttt ctgtggctgg ctctaccttc 3950

 ctgtccctga ggttaaacgg tgcccatcct gccatcctca aacgacagag 4000

 gagcttttct ggaatttcaa accattgctc ttagtcccaa gctaggctta 4050

 aacctggaat ctacaagcca aaagtccctc cctgcctgag ggcagtaccc 4100

 tccattgggc acagtccaga cccaagtcaa agatgcccca ttccttgcgc 4150

 ctcagccctc agttccttca tttccaccag gccgtgcctt gtttgagttt 4200

 ttcctcccag tgagactgcc ccacggagac agaggaaagg gctggctccc 4250

 cctccccagg ctggagaccc cccccaactc caggaaagag cagtcagagt 4300

 ccagtgctct gcctcagacg ttgcctgaga agaagtggct gccacaccca 4350

 ggggaaggcc ctgaggcgga ggctgtgctc cgccatggtg tcccggtacc 4400

 ttccatacac agaggagtgc agccttctcc atatctccat ggccctgtcc 4450

 caggccggcc cagatgtgtc ccccccaggc cttgtcctac gtccaaggtg 4500

 gcagatgtct tccctgggct gccaccagcc cccgccccag agtggcccac 4550

 cgtggcacta gaatgcaagt atcctgcgac cttgcaacct caccttcctg 4600

 tgggtgttct ttcctgccct gtccaaaagc gccctcacta ttcttggacc 4650

 atgccagatt ctgcctctct ggaaagaggc tctggacagc agaagcctcc 4700

 aagcacagag cctggcccca ggccccagac agggtgggct tcctgccctt 4750

 ccctctgggc acgcctgctg gccgacccac tgacccactc ggatggacca 4800

 acctgctctg tccccaaagg acgcctgcag gagagagcag cactccgcat 4850

 cacctcacca aggatcggac tctgcccctg gacctgggaa cgactggact 4900

 gtcacggggt tccctcctag ctctcccagt gaactcctgc caggcacaca 4950

 cagcccctat agcactgagc tcacatggga ctgggatatg ggggcatctc 5000

 ttccccagag aggcactcag tgagcctcct gtgcctggcc ccagtctggg 5050

 ccatctctta ggtgagacag ttgcccgaaa ctaagccagg cctggctgga 5100

 ggagcagcag cttggggaga gggatttccc tgcagacctc aagccatcat 5150

 gcggtgggtg ctgccatgac agaggctgca cccctgggcc agcggggctg 5200

 ctcacccacc tcttgtgcaa ggtggccttt gtgctgcgcc tgcaggcaga 5250

 gctggagccc ccagcagagg caggctggga cggaccagca tctggaagat 5300

 gtacatagtt atttttctct ttgtggtttc ttgtttggtt tggtttgctt 5350

 ttgacagctt cattttattt ttgacgtcac tttttggcca tgtaaactat 5400

 ttgtggcaat tttatgtttt tatttatgaa taaagaatgc catttctcac 5450

 gccctctaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 5492

<210> 34
<211> 596
<212> PRT
<213> Homo sapien

<400> 34
 Met Gly Ser Val Ser Ser Leu Ile Ser Gly His Ser Phe His Ser
   1               5                  10                  15

 Lys His Cys Arg Ala Ser Gln Tyr Lys Leu Arg Lys Ser Ser His
                  20                  25                  30

 Leu Lys Lys Leu Asn Arg Tyr Ser Asp Gly Leu Leu Arg Phe Gly
                  35                  40                  45

 Phe Ser Gln Asp Ser Gly His Gly Lys Ser Ser Ser Lys Met Gly
                  50                  55                  60

 Lys Ser Glu Asp Phe Phe Tyr Ile Lys Val Ser Gln Lys Ala Arg
                  65                  70                  75

 Gly Ser His His Pro Asp Tyr Thr Ala Leu Ser Ser Gly Asp Leu
                  80                  85                  90

 Gly Gly Gln Ala Gly Val Asp Phe Asp Pro Ser Thr Pro Pro Lys
                  95                 100                 105

 Leu Met Pro Phe Ser Asn Gln Leu Glu Met Gly Ser Glu Lys Gly
                 110                 115                 120

 Ala Val Arg Pro Thr Ala Phe Lys Pro Val Leu Pro Arg Ser Gly
                 125                 130                 135

 Ala Ile Leu His Ser Ser Pro Glu Ser Ala Ser His Gln Leu His
                 140                 145                 150

 Pro Ala Pro Pro Asp Lys Pro Lys Glu Gln Glu Leu Lys Pro Gly
                 155                 160                 165

 Leu Cys Ser Gly Ala Leu Ser Asp Ser Gly Arg Asn Ser Met Ser
                 170                 175                 180

 Ser Leu Pro Thr His Ser Thr Ser Ser Ser Tyr Gln Leu Asp Pro
                 185                 190                 195

 Leu Val Thr Pro Val Gly Pro Thr Ser Arg Phe Gly Gly Ser Ala
                 200                 205                 210

 His Asn Ile Thr Gln Gly Ile Val Leu Gln Asp Ser Asn Met Met
                 215                 220                 225

 Ser Leu Lys Ala Leu Ser Phe Ser Asp Gly Gly Ser Lys Leu Gly
                 230                 235                 240

 His Ser Asn Lys Ala Asp Lys Gly Pro Ser Cys Val Arg Ser Pro
                 245                 250                 255

 Ile Ser Thr Asp Glu Cys Ser Ile Gln Glu Leu Glu Gln Lys Leu
                 260                 265                 270

 Leu Glu Arg Glu Gly Ala Leu Gln Lys Leu Gln Arg Ser Phe Glu
                 275                 280                 285

 Glu Lys Glu Leu Ala Ser Ser Leu Ala Tyr Glu Glu Arg Pro Arg
                 290                 295                 300

 Arg Cys Arg Asp Glu Leu Glu Gly Pro Glu Pro Lys Gly Gly Asn
                 305                 310                 315

 Lys Leu Lys Gln Ala Ser Gln Lys Ser Gln Arg Ala Gln Gln Val
                 320                 325                 330

 Leu His Leu Gln Val Leu Gln Leu Gln Gln Glu Lys Arg Gln Leu
                 335                 340                 345

 Arg Gln Glu Leu Glu Ser Leu Met Lys Glu Gln Asp Leu Leu Glu
                 350                 355                 360

 Thr Lys Leu Arg Ser Tyr Glu Arg Glu Lys Thr Ser Phe Gly Pro
                 365                 370                 375

 Ala Leu Glu Glu Thr Gln Trp Glu Val Cys Gln Lys Ser Gly Glu
                 380                 385                 390

 Ile Ser Leu Leu Lys Gln Gln Leu Lys Glu Ser Gln Thr Glu Val
                 395                 400                 405

 Asn Ala Lys Ala Ser Glu Ile Leu Gly Leu Lys Ala Gln Leu Lys
                 410                 415                 420

 Asp Thr Arg Gly Lys Leu Glu Gly Leu Glu Leu Arg Thr Gln Asp
                 425                 430                 435

 Leu Glu Gly Ala Leu Arg Thr Lys Gly Leu Glu Leu Glu Val Cys
                 440                 445                 450

 Glu Asn Glu Leu Gln Arg Lys Lys Asn Glu Ala Glu Leu Leu Arg
                 455                 460                 465

 Glu Lys Val Asn Leu Leu Glu Gln Glu Leu Gln Glu Leu Arg Ala
                 470                 475                 480

 Gln Ala Ala Leu Ala Arg Asp Met Gly Pro Pro Thr Phe Pro Glu
                 485                 490                 495

 Asp Val Pro Ala Leu Gln Arg Glu Leu Glu Arg Leu Arg Ala Glu
                 500                 505                 510

 Leu Arg Glu Glu Arg Gln Gly His Asp Gln Met Ser Ser Gly Phe
                 515                 520                 525

 Gln His Glu Arg Leu Val Trp Lys Glu Glu Lys Glu Lys Val Ile
                 530                 535                 540

 Gln Tyr Gln Lys Gln Leu Gln Gln Ser Tyr Val Ala Met Tyr Gln
                 545                 550                 555

 Arg Asn Gln Arg Leu Glu Lys Ala Leu Gln Gln Leu Ala Arg Gly
                 560                 565                 570

 Asp Ser Ala Gly Glu Pro Leu Glu Val Asp Leu Glu Gly Ala Asp
                 575                 580                 585

 Ile Pro Tyr Glu Asp Ile Ile Ala Thr Glu Ile
                 590                 595

<210> 35
<211> 2446
<212> DNA
<213> Homo sapien

<400> 35
 ggccgggcgg gcatgggcct tcccggcccg gagctgggag tcgaaggggc 50

 gggaggcgtg atggtgaact cgcaagaagt ttgagggacg cgcgggcccc 100

 gcgcccactc cccctccacc ggacacggct ggggccggcg atgcctgaga 150

 gggggtcgga ggacgcagtg aacatatatg catgtacagt gtggatcctc 200

 atctgagagg agggagatga aaacacaccc acctcacagg ctgttgtgag 250

 gactaagggt gcggcagtgc ctggtacatg ggagccagcg ccggcagcca 300

 ccatggcgtc acgcataggg ttgcgcatgc agctcatgcg ggagcaggcg 350

 cagcaggagg agcagcggga gcgcatgcag caacaggctg tcatgcatta 400

 catgcagcag cagcagcagc agcaacagca gcagctcgga gggccgccca 450

 ccccggccat caataccccc gtccacttcc agtcgccacc acctgtgcct 500

 ggggaggtgt tgaaggtgca gtcctacctg gagaatccca catcctacca 550

 tctgcagcag tcgcagcatc agaaggtgcg ggagtacctg tccgagacct 600

 atgggaacaa gtttgctgcc cacatcagcc cagcccaggg ctctccgaaa 650

 cccccaccag ccgcctcccc aggggtgcga gctggacacg tgctgtcctc 700

 ctccgctggc aacagtgctc ccaatagccc catggccatg ctgcacattg 750

 gctccaaccc tgagagggag ttggatgatg tcattgacaa cattatgcgt 800

 ctggacgatg tccttggcta catcaatcct gaaatgcaga tgcccaacac 850

 gctacccctg tccagcagcc acctgaatgt gtacagcagc gacccccagg 900

 tcacagcctc cctggtgggc gtcaccagca gctcctgccc tgcggacctg 950

 acccagaagc gagagctcac agatgctgag agcagggccc tggccaagga 1000

 gcggcagaag aaagacaatc acaacttaat tgaaaggaga cgaaggttca 1050

 acatcaatga ccgcatcaag gagttgggaa tgctgatccc caaggccaat 1100

 gacctggacg tgcgctggaa caagggcacc atcctcaagg cctctgtgga 1150

 ttacatccgg aggatgcaga aggacctgca aaagtccagg gagctggaga 1200

 accactctcg ccgcctggag atgaccaaca agcagctctg gctccgtatc 1250

 caggagctgg agatgcaggc tcgagtgcac ggcctcccta ccacctcccc 1300

 gtccggcatg aacatggctg agctggccca gcaggtggtg aagcaggagc 1350

 tgcctagcga agagggccca ggggaggccc tgatgctggg ggctgaggtc 1400

 cctgaccctg agccactgcc agctctgccc ccgcaagccc cgctgcccct 1450

 gcccacccag ccaccatccc cattccatca cctggacttc agccacagcc 1500

 tgagctttgg gggcagggag gacgagggtc ccccgggcta ccccgaaccc 1550

 ctggcgccgg ggcatggctc cccattcccc agcctgtcca agaaggatct 1600

 ggacctcatg ctcctggacg actcactgct accgctggcc tctgatccac 1650

 ttctgtccac catgtccccc gaggcctcca aggccagcag ccgccggagc 1700

 agcttcagca tggaggaggg cgatgtgctg tgaccctggc tgcccctgtg 1750

 ccagggaaca ggggccggcc tgggggctgg gagggccagg ggcacctccc 1800

 tcccaccctt caggctgcac tgtgtgtgaa gtagccacct gccctgcctc 1850

 cctcctcccc gttggcccct gtttggactt agtgcctgtc tggcagcctg 1900

 tggggtcagg agaagcaccc ccagggcagc cctcttgact ggcgcagtgg 1950

 gaagaggcct tcagcccctc tcccggagat ggaatcgcgg ggcagggagg 2000

 ggcagggtgt tctagaggtg agaagagggc ctggtggaga ttccctgtct 2050

 tctgagcccg agcccctcat taccagtgaa ggacatgctt gaggggttcg 2100

 ggaagctcct catctgaggc aactggtcct gggggtgctc aggcctgcct 2150

 ttttgggact cagatggcag gaggtccacc ccgcagcctg gtcctcggct 2200

 ctcccacagg tgggcacccc ccactttggt gctaatagct ctccaccagg 2250

 tggtgtgagc gcgggggctg ccagaagcgg gaggggtcac tgccggaaga 2300

 gcagctgccc tccgacccct cactttgtgc ctttagtaaa cactgtgctt 2350

 tgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2400

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 2446

<210> 36
<211> 476
<212> PRT
<213> Homo sapien

<400> 36
 Met Ala Ser Arg Ile Gly Leu Arg Met Gln Leu Met Arg Glu Gln
   1               5                  10                  15

 Ala Gln Gln Glu Glu Gln Arg Glu Arg Met Gln Gln Gln Ala Val
                  20                  25                  30

 Met His Tyr Met Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Leu
                  35                  40                  45

 Gly Gly Pro Pro Thr Pro Ala Ile Asn Thr Pro Val His Phe Gln
                  50                  55                  60

 Ser Pro Pro Pro Val Pro Gly Glu Val Leu Lys Val Gln Ser Tyr
                  65                  70                  75

 Leu Glu Asn Pro Thr Ser Tyr His Leu Gln Gln Ser Gln His Gln
                  80                  85                  90

 Lys Val Arg Glu Tyr Leu Ser Glu Thr Tyr Gly Asn Lys Phe Ala
                  95                 100                 105

 Ala His Ile Ser Pro Ala Gln Gly Ser Pro Lys Pro Pro Pro Ala
                 110                 115                 120

 Ala Ser Pro Gly Val Arg Ala Gly His Val Leu Ser Ser Ser Ala
                 125                 130                 135

 Gly Asn Ser Ala Pro Asn Ser Pro Met Ala Met Leu His Ile Gly
                 140                 145                 150

 Ser Asn Pro Glu Arg Glu Leu Asp Asp Val Ile Asp Asn Ile Met
                 155                 160                 165

 Arg Leu Asp Asp Val Leu Gly Tyr Ile Asn Pro Glu Met Gln Met
                 170                 175                 180

 Pro Asn Thr Leu Pro Leu Ser Ser Ser His Leu Asn Val Tyr Ser
                 185                 190                 195

 Ser Asp Pro Gln Val Thr Ala Ser Leu Val Gly Val Thr Ser Ser
                 200                 205                 210

 Ser Cys Pro Ala Asp Leu Thr Gln Lys Arg Glu Leu Thr Asp Ala
                 215                 220                 225

 Glu Ser Arg Ala Leu Ala Lys Glu Arg Gln Lys Lys Asp Asn His
                 230                 235                 240

 Asn Leu Ile Glu Arg Arg Arg Arg Phe Asn Ile Asn Asp Arg Ile
                 245                 250                 255

 Lys Glu Leu Gly Met Leu Ile Pro Lys Ala Asn Asp Leu Asp Val
                 260                 265                 270

 Arg Trp Asn Lys Gly Thr Ile Leu Lys Ala Ser Val Asp Tyr Ile
                 275                 280                 285

 Arg Arg Met Gln Lys Asp Leu Gln Lys Ser Arg Glu Leu Glu Asn
                 290                 295                 300

 His Ser Arg Arg Leu Glu Met Thr Asn Lys Gln Leu Trp Leu Arg
                 305                 310                 315

 Ile Gln Glu Leu Glu Met Gln Ala Arg Val His Gly Leu Pro Thr
                 320                 325                 330

 Thr Ser Pro Ser Gly Met Asn Met Ala Glu Leu Ala Gln Gln Val
                 335                 340                 345

 Val Lys Gln Glu Leu Pro Ser Glu Glu Gly Pro Gly Glu Ala Leu
                 350                 355                 360

 Met Leu Gly Ala Glu Val Pro Asp Pro Glu Pro Leu Pro Ala Leu
                 365                 370                 375

 Pro Pro Gln Ala Pro Leu Pro Leu Pro Thr Gln Pro Pro Ser Pro
                 380                 385                 390

 Phe His His Leu Asp Phe Ser His Ser Leu Ser Phe Gly Gly Arg
                 395                 400                 405

 Glu Asp Glu Gly Pro Pro Gly Tyr Pro Glu Pro Leu Ala Pro Gly
                 410                 415                 420

 His Gly Ser Pro Phe Pro Ser Leu Ser Lys Lys Asp Leu Asp Leu
                 425                 430                 435

 Met Leu Leu Asp Asp Ser Leu Leu Pro Leu Ala Ser Asp Pro Leu
                 440                 445                 450

 Leu Ser Thr Met Ser Pro Glu Ala Ser Lys Ala Ser Ser Arg Arg
                 455                 460                 465

 Ser Ser Phe Ser Met Glu Glu Gly Asp Val Leu
                 470                 475

<210> 37
<211> 3900
<212> DNA
<213> Homo sapien

<400> 37
 cgatggccct gcccagtccc agacagaacc tactacgtgc ggcggcagct 50

 ggggcgggaa ggcgggcgct gggggcgctg cggccgctgc agcgcagggt 100

 ccacctggtc ggctgcacct gtggaggagg aggtggattt caggcttccc 150

 gtagactgga agaatcggct caaaaccgct tgcctcgcag gggctgagct 200

 ggaggcagcg aggccgcccg acgcaggctt ccggcgagac atggcagggc 250

 aaggatggca gcccggcggc agggcccggc gaggagcgcg aacccgcggc 300

 cgcagttccc aggcgtctgc gggcgcgagc acgccgcgac cctgcgtgcg 350

 ccggggcggg ggggcggggc ctcgcctgca caaataggga cgagggggcg 400

 gggcggccac aatttcgcgc caaacttgac cgcgcgttct gctgtaacga 450

 gcgggctcgg aggtcctccc gctgctgtca tggttggttc gctaaactgc 500

 atcgtcgctg tgtcccagaa catgggcatc ggcaagaacg gggacctgcc 550

 ctggccaccg ctcaggaatg aattcagata tttccagaga atgaccacaa 600

 cctcttcagt agaaggtaaa cagaatctgg tgattatggg taagaagacc 650

 tggttctcca ttcctgagaa gaatcgacct ttaaagggta gaattaattt 700

 agttctcagc agagaactca aggaacctcc acaaggagct cattttcttt 750

 ccagaagtct agatgatgcc ttaaaactta ctgaacaacc agaattagca 800

 aataaagtag acatggtctg gatagttggt ggcagttctg tttataagga 850

 agccatgaat cacccaggcc atcttaaact atttgtgaca aggatcatgc 900

 aagactttga aagtgacacg ttttttccag aaattgattt ggagaaatat 950

 aaacttctgc cagaataccc aggtgttctc tctgatgtcc aggaggagaa 1000

 aggcattaag tacaaatttg aagtatatga gaagaatgat taatatgaag 1050

 gtgttttcta gtttaagttg ttccccctcc ctctgaaaaa agtatgtatt 1100

 tttacattag aaaaggtttt ttgttgactt tagatctata attatttcta 1150

 agcaacttgt ttttattccc cactactctt ctctctatca gataccattt 1200

 atgagacatt cttgctataa ctaagtgctt ctccaagacc ccaactgagt 1250

 ccccagcacc tgctacagtg agctgccatt ccacacccat cacatgtggc 1300

 actcttgcca gtccttgaca ttgtcgggct tttcacatgt tggtaatatt 1350

 tattaaagat gaagatccac atacccttca actgagcagt ttcactagtg 1400

 gaaataccaa aagcttccta cgtgtatatc cagaggtttg tagataaatg 1450

 ttgccacctt gtttgtaaca gtgaaaaatt gaaaacaacc tggaagtcca 1500

 gtgatgggaa aatgagtatg tttctgtctt agattgggga acccaaagca 1550

 gattgcaaga ctgaaatttc agtgaaagca gtgtatttgc taggtcatac 1600

 cagaaatcat caattgaggt acggagaaac tgaactgaga aggtaagaaa 1650

 agcaatttaa agtcagcgag caggttctca ttgataacaa gctccatact 1700

 gctgagatac agggaaatgg aggggggaaa gctggagtat tgatcccgcc 1750

 cccctccttg gttgtcagct ccctgtcctg tgtgtgggcg gaacatagtc 1800

 cagctgctct atagcaagtc tcaggtgttt gcagtaagaa gctgctggca 1850

 tgcacgggaa cagtgaatgc caaacactta aagcaattcg atgtttaagt 1900

 atgtaagttc tttttttttt agacagcgtt tcgctcttgt tgcccaggct 1950

 agcatgcaat ggtgtgacct cggcttactg caacctccgc cttcccagat 2000

 tcaagcgatt ctcctgcctc aggctcccaa gtagctagga ccaggtgcgc 2050

 gccaccacgc ccggctaatt tttgtatttt gtatttttag tagagatggg 2100

 gtttcaccat gttggtcagg ctagtctcga actcgtgacc gcaagcgatt 2150

 cacccacctc agcctcccaa agtgctggga ttaccggctt gagccaccac 2200

 acccggcaca tcttcattct ttttatgtag taaaaagtat aaggccacac 2250

 atggtttatt tgaagtattt tataatttaa aaaaatacag aagcaggaaa 2300

 accaattata agttcaagtg agggatgatg gttgcttgaa ccaaagggtt 2350

 gcatgtagta agaaattgtg atttaagata tattttaaag ttataagtag 2400

 caggatattc tgatggagtt tgactttggt tttgggccca gggagtttca 2450

 gatgcctttg agaaatgaat gaagtagaga gaaaataaaa gaaaaaccag 2500

 ccaggcacag tggctcacac ctgtaatccc agcgctttgg gaggctaagg 2550

 caggcagatc acttgagacc agcttgggca acatggcaaa gccccatctc 2600

 tacaaaaaac acaaaaatta gctgggcatt gtggcgcaca cctgtattcc 2650

 catctagtca ggaagctgag atggaagaat taattgagcc cacgagttca 2700

 aggctgcagt gagtcgtgat tgtgccactg cactccagcc ggggtgacag 2750

 aagagacctt gtctcgaaaa cgaatctgaa aacaatggaa ccatgccttc 2800

 ataattctag aaagttattt tcaactgata aatctatatt cacccaaata 2850

 atcaagggtg aaggtaaaat aatacatttt tagacaagca aagactcagg 2900

 ggttacctcc atgtgccctt tttagggaag ctgttggaga aaatactcca 2950

 gcaaaatgaa ggagtacaca aaccagagaa tgacatgaat ccagcaaata 3000

 ggatccaaca caggcaatat tccagctatg gagctagctt taaaaaggaa 3050

 cagtaaaaat attaatcggt tagctgggtg gaatggccca tgcctgtagt 3100

 cccagctact caggaggctc agcagcagga cgacttgagc ccaagagttc 3150

 cagaccagcc tggccacctt agtgagatcc cttctcttaa aaataataac 3200

 ttattgccag atttggggca tttggaaaga agttcattga agataaagca 3250

 aaagtaaaaa aaaaaaaaaa aaaaacaagg ggaaagggtt ggttaggcaa 3300

 tcattctagg gcagaaagaa gtacaggata ggaagagcat aatacactgt 3350

 ttttctcaac aaggagcagt atgtacacag tcataatgat gtgactgctt 3400

 agcccctaaa tatggtaact actctgggac aatatgggag gaaaagtgaa 3450

 gattgtgatg gtgtaagagc taatcctcat ctgtcatatc cagaaatcac 3500

 tatataatat ataataatga aatgactaag ttatgtgagg aaaaaaacag 3550

 aagacattgc taaaagagtt aaaagtcatt gctctggaga attaggaggg 3600

 atggggcagg ggactgttag gatgcattat aaactgaaaa gcctttttaa 3650

 aattttatgt attaatatat gcattcactt gaaaaactaa aaaaaaacaa 3700

 taatttggaa aaacccatga aggtaactaa cggaaggaaa aactaagaga 3750

 atgaaaagta tttgcctctg gaaagaacaa ctggcaggac tgttgttttc 3800

 attgtaagac ttttggagcc atttaattgt acttaaccat tttcatctat 3850

 ttctttaata agaacaattc catcttaata aagagttaca cttgttaata 3900

<210> 38
<211> 187
<212> PRT
<213> Homo sapien

<400> 38
 Met Val Gly Ser Leu Asn Cys Ile Val Ala Val Ser Gln Asn Met
   1               5                  10                  15

 Gly Ile Gly Lys Asn Gly Asp Leu Pro Trp Pro Pro Leu Arg Asn
                  20                  25                  30

 Glu Phe Arg Tyr Phe Gln Arg Met Thr Thr Thr Ser Ser Val Glu
                  35                  40                  45

 Gly Lys Gln Asn Leu Val Ile Met Gly Lys Lys Thr Trp Phe Ser
                  50                  55                  60

 Ile Pro Glu Lys Asn Arg Pro Leu Lys Gly Arg Ile Asn Leu Val
                  65                  70                  75

 Leu Ser Arg Glu Leu Lys Glu Pro Pro Gln Gly Ala His Phe Leu
                  80                  85                  90

 Ser Arg Ser Leu Asp Asp Ala Leu Lys Leu Thr Glu Gln Pro Glu
                  95                 100                 105

 Leu Ala Asn Lys Val Asp Met Val Trp Ile Val Gly Gly Ser Ser
                 110                 115                 120

 Val Tyr Lys Glu Ala Met Asn His Pro Gly His Leu Lys Leu Phe
                 125                 130                 135

 Val Thr Arg Ile Met Gln Asp Phe Glu Ser Asp Thr Phe Phe Pro
                 140                 145                 150

 Glu Ile Asp Leu Glu Lys Tyr Lys Leu Leu Pro Glu Tyr Pro Gly
                 155                 160                 165

 Val Leu Ser Asp Val Gln Glu Glu Lys Gly Ile Lys Tyr Lys Phe
                 170                 175                 180

 Glu Val Tyr Glu Lys Asn Asp
                 185

<210> 39
<211> 6322
<212> DNA
<213> Homo sapien

<400> 39
 ctgagagcga catgtccccg gcggctcagg cggagcggcc cgtggcgctg 50

 tttttctgag tccggggtgg cctggcagcc ggccgaggac gagggtcggc 100

 gggggctgcc cccgtggtgg tggccgccat gctgggagcc tgggcggttg 150

 agggaaccgc tgtggcgctc ctgcgactgc tgctgctgct gctgccgccg 200

 gcgatccggg gacccgggct cggcgtggcc ggcgtggccg gcgcggcggg 250

 ggccgggctg cccgagagcg tcatttgggc ggtcaacgcg ggtggagagg 300

 cgcatgtgga cgtgcacggg atccacttcc gcaaggaccc tttggaaggc 350

 cgggtgggcc gagcctcaga ctatggcatg aaactgccaa tcctgcgttc 400

 caaccctgag gaccagatcc tgtatcaaac tgagcggtac aatgaggaga 450

 cctttggcta cgaagtgccc atcaaagagg agggggacta cgtgctggtc 500

 ttgaaatttg cagaggtcta ctttgcacag tcccagcaaa aggtatttga 550

 tgtacgattg aatggccacg tcgtggtgaa ggacttggat atctttgatc 600

 gtgttgggca tagcacagct cacgatgaaa ttatacctat gagcatcaga 650

 aaggggaagc tgagtgtcca gggggaggtg tccaccttca cagggaaact 700

 ctacattgag tttgtcaagg ggtactatga caatcccaag gtctgtgcac 750

 tctacatcat ggctgggaca gtggatgatg taccaaagct tcagcctcat 800

 ccgggattgg agaagaaaga agaggaagaa gaagaagaag aatatgatga 850

 agggtctaat ctcaaaaaac agaccaataa gaaccgggtg cagtcaggcc 900

 cccgcacacc caacccctat gcctcggaca acagcagcct catgtttccc 950

 atcctggtgg ccttcggagt cttcattcca accctcttct gcctctgccg 1000

 gttgtgagaa caaatgacta tcctgaacag ggtggagggg tgtgggaaag 1050

 aaaccagcca tattggtttt ggtttctgta tttttcacaa tgattaatga 1100

 acaaaaacaa agagaaaaaa aacacacatc aattaaagga gacaaaaaga 1150

 ggcagagcga gtagagagca gccctcattc accacctggt cccagacgtg 1200

 cttcagtcct cgtcctctct ttgtggctgg ctcccagcct tctctttcct 1250

 cttgaggata cttagggtaa actggatcct tcctgctcaa ggatcctcat 1300

 ttgtatacct agtggaaagg actctgaact cagaggagtc actgttcctt 1350

 tttttaggtt agaaattaac agcagggaaa tgccatctta ttacctgaga 1400

 cgaccagcac tgggagttag gtacggtctg aagttatgtc tagataagac 1450

 ttcagacgtc ctgggattga aagaatgtgt gtgaaggggt agaatttgtg 1500

 cggtaaagac ttaaaaaaaa aagtagggag attaaaaaaa aagaaagaaa 1550

 atgcttcctt atctggaagc ctttctggat taatccagtg atggtcccac 1600

 ctttagtgtt tgagctttgt cattgcttgt ctccctggca tgtgccagtt 1650

 atagactgtc cagcatccaa gacgtttcgg ttatgtcggg tcctcagatc 1700

 gcctctgact tgttaccaca acaaatcatt ttgatttcag tgcctgttgg 1750

 ggacttgatt tcttctcagg ttttgtttgt ttgtttgttt ccttaatctg 1800

 gctcatttga aatttcttct ccctctcaac catcccacta agttatagcc 1850

 aagaagggaa ggagacacgg ggatttgggg ttctctgctt gaatgtcttc 1900

 tcctttacca cctcaccttg ttggtacctc cctccctgga tctctgagcc 1950

 agcagccagg aggacctgac ccagcagttc tttactggcc cctttgtagg 2000

 gccttgctgc cagggggcag ggatgctttc cagcctgcag caacagaaca 2050

 cttgacctta aaagtctctt ctggtctttg gattagaaaa ggcttatgtt 2100

 agcatagctt aagagcaacc tcagagactt gagccctact aagtgactga 2150

 ccactgttta gagtgtctgg tatctgatgt tcatttattc ccatgttctt 2200

 gtgtgtcaca gttcagccag ttttggttta tgcctagagc tacttcaagg 2250

 aactagacta attagctata taggcccagc gatgcttctt attgatctta 2300

 atagtatgcc cttccttccc ctgtcctttc atttctctat ccaagtagca 2350

 gtcaggttct tggtgtgatg ggactgaaag aattccagtc agccagagcc 2400

 ttggcagctc tgaagctaac cttagcatct aagtgtcgat cttgaattcc 2450

 ctgaaaaaat ttctatagga aatgaagctt ccctggtccc ctcctttctg 2500

 gccattgtca tccatttccc agttagggca acaatgaagg aggacccagc 2550

 caagctagaa ggaattttgt ggatgggaga cagcaggatt agcttcagct 2600

 tgggctggag cagtcaatat aggatctcag gccaggcccg cttttctaga 2650

 atgtgtttaa ttttgagttt gctttattag atatgttttt taagagctct 2700

 gtatatttga actgctcctt atgtgacaaa ataggtagct cttgggctca 2750

 tgtcctgggt tttggctctt taatgattac tccaggccag catttagtcg 2800

 tttgagaatt gtagcctgtt gttttcgctg tgacttgggt ctcagtgcta 2850

 gggtattgag tcaggcagct ggagggttgt ggcccgaggc tgcagtcaga 2900

 ggtatacttc ccatagtgct tcacacagct cccctgcttc taaaggataa 2950

 ggtactgtag ccttggtcct ggggaccacc tgcctggggc agtggacatc 3000

 ctaactaaac aggcttctgg cagtagcttt ggttcctatc ccatcgaaat 3050

 tccccaaagc cctgggccac tgccattggg ttagtcaaga tgaaggagga 3100

 ggactggctg cctccatttt gccttgtttg ttagtttgcc tgggtctgtc 3150

 tgaggaagga gggggtcccg ccttccacct caacacatcc cttcagtgac 3200

 tcagagtctc agaaggaaac cctgactcct ggggccattt cctaatggta 3250

 ctgtaagcca agcagctttg cttctgcctc tgtttccaag cccacccttt 3300

 tcccctgagc tcagggttag ggatgggcgc tttcctctct ggttgtgaac 3350

 gaaaggaagg aacatctttc tatggctaac aaaaactaaa ggggaagtga 3400

 ggaaacagga agaagtatgg tgggggctgg ggtagactcc cctggagcca 3450

 agcctatcca gctaacaaga gctccctggg gctggtcaca gctggctcat 3500

 gatgctgaac ttgaaagttt ttttgttttt gtttttgttt tgtggctcct 3550

 ccaagatata ggtacatgaa gtttaggtta aaggggtggg attctttatt 3600

 tttatttttg tattgtatgt gtcaagaatt actctgttgt tcaccttttg 3650

 ctttttgcac tgtttgttct cttatctgta ttttgagctt agtgctagga 3700

 ctgagaggct gcaccatagg gaatgtatgg gagatggtga ggggtgccag 3750

 tgaggggtgc gtggaggaga ggcctgggct cctctactgg atctacactc 3800

 tgtcccaggt ttttagatcc cactgagccc agctgactga aaacaaggac 3850

 agtcagggtg aaacttcttt tgccagaagt gtggcctgag ttgaatttct 3900

 gggaggatga cgcagatgtc tgctgcagag ctgggctgag agttctgcag 3950

 tctagctctg acttaggtca ggggcctgtt ggtctctcat tggacgtttt 4000

 tgggtctcac tcatgcttac tgaaacattg tgccaagaaa ctctgtggga 4050

 tttgtgtccc ttaaaccaga ctcacttttc tgaaaaatct ccattgttga 4100

 ggagaggctg ctcaatcgac accccgagtt ctcatgactg ggaagatagt 4150

 tttcttcagg tgtcaatggc gttagactcc caggaagact agccctgccc 4200

 acagggccac ctgttggttt gagagcgtgt tcgtgttctc ttgccctccc 4250

 tgcctaagag ctactgggat cacgttagcg ggcatttagg ctttgatgag 4300

 agggcacagt ttgagttagg tttacctccc cctttctgtg cctgggaact 4350

 gtttggtcca gctttagaac tgtggttttg acttccttat ctcttgggag 4400

 aagcttctgt tttaaggaat ttctcttcct tcttctcctg cctctagcct 4450

 ctcctggaaa ggcctggata tggtttctaa aatctcagct gagaacttca 4500

 gaaaacagca gcagtatttt ccttttccta gtgctaaaat ccctttccct 4550

 agaaattggc tcaccttggg aaacccaggg aaagaatcag caggttctct 4600

 gccctcccta ggggttgggg aaggacccac cccggtcagc acagtgcctt 4650

 ttcctctcct gctctgagcc agggtggggc attccctcta gattcaggtt 4700

 tgggcagggg tcctatagtc cctgccatgg ggctgcttcc ctgtcccttc 4750

 cctccccttt gctggcctac tctggcataa ttcaagtgtc ttcttgcctt 4800

 ggggatcctt agtggcatca aatggcaaca tggaatattg tcctccatgc 4850

 ccctccagaa ggacctagga gagtaggtga gctttccaaa gtgagagacg 4900

 aatctttctt tctttttttt tttaaagggc aggatgggta tgctttgggc 4950

 tttctccttc tgtggccccg gaggaaggag agactgaggc aaggcaaagt 5000

 gatagtacac tgaagcagaa ccggaaacac ccaggaactg ttcagaaatc 5050

 tcagaagaaa tctgcttctc ttcgatggaa agatataatt aacgatcaaa 5100

 gagctctaag aaaattgcaa agaagcctta atgttcaagc tttagaaaga 5150

 tcagagcaat ttttctcttt cagtccaaac taagactctc tgtatttaaa 5200

 tctctctggg gcaagagggc tagatttcct cattttgtta tgagactaga 5250

 ttggtaccag tagatcagct gcctagcgag ggcaggtttc ttctttgcat 5300

 ctgtgtggct tgcttccagt ctggcctgtc ctttccagct gccttttgtc 5350

 tagcctgcta tggggggcca gattatcttg ataagagcag gtgatttggg 5400

 gactagctgg gttggtagga aaagagcagg atggatctct tgggacaggt 5450

 tcccccagga gtataaacac aaggagccag gattgtcctg gcagccaagg 5500

 aaacagtagt gcctgtttga gttggcagag agggccttgg cacctcttgc 5550

 atccaggcag tcttgtgaga tgggggcaca tagcactggg gaaagcagaa 5600

 ctccattctc acctctattt tgagcttcag tgctttattt cagtatgagg 5650

 aaaaacaaca acaaactgaa gtgcgctttc cgtcctttca aaggacaact 5700

 gtcgggaagg gagagccgag ttgcgaggta ggaggggagc actggcaggg 5750

 agagacattc ttgactcctc tcttccctgg tgtgttgtga tccagggaat 5800

 gaaaagaaat ttgaccctgg attggttctc tccttggact taaggaatct 5850

 taccttttcc ttccacaaag ttctcccagg caaggaccag ctgcccattc 5900

 tgagcccagg gcagcctctt caaccattat tggtctaacc tggcttgtca 5950

 ggaaaccaag cccacccttc cacattgggc ctggctgctc tattctgtac 6000

 caagtactgg agaaaaagca tcaagttctt agcccttgta gcttctaccc 6050

 tagtttccca tcctctctct gtggaggcca aaccaactct ttgccagcag 6100

 ccacaacatg cattgacagc ggcacagtga gatataactg atgggctttg 6150

 aacctggttg gccggggaag ctgtaggggt ggatagagct ggctttcctt 6200

 ctgggctgtc tccatctgac cctacccctt ccatgtccca ccccactccc 6250

 accaaaaagt acaaaatcag gatgtttttc actgtccatt gctttgtgtt 6300

 ttaataaaca atttgcagtg ac 6322

<210> 40
<211> 292
<212> PRT
<213> Homo sapien

<400> 40
 Met Leu Gly Ala Trp Ala Val Glu Gly Thr Ala Val Ala Leu Leu
   1               5                  10                  15

 Arg Leu Leu Leu Leu Leu Leu Pro Pro Ala Ile Arg Gly Pro Gly
                  20                  25                  30

 Leu Gly Val Ala Gly Val Ala Gly Ala Ala Gly Ala Gly Leu Pro
                  35                  40                  45

 Glu Ser Val Ile Trp Ala Val Asn Ala Gly Gly Glu Ala His Val
                  50                  55                  60

 Asp Val His Gly Ile His Phe Arg Lys Asp Pro Leu Glu Gly Arg
                  65                  70                  75

 Val Gly Arg Ala Ser Asp Tyr Gly Met Lys Leu Pro Ile Leu Arg
                  80                  85                  90

 Ser Asn Pro Glu Asp Gln Ile Leu Tyr Gln Thr Glu Arg Tyr Asn
                  95                 100                 105

 Glu Glu Thr Phe Gly Tyr Glu Val Pro Ile Lys Glu Glu Gly Asp
                 110                 115                 120

 Tyr Val Leu Val Leu Lys Phe Ala Glu Val Tyr Phe Ala Gln Ser
                 125                 130                 135

 Gln Gln Lys Val Phe Asp Val Arg Leu Asn Gly His Val Val Val
                 140                 145                 150

 Lys Asp Leu Asp Ile Phe Asp Arg Val Gly His Ser Thr Ala His
                 155                 160                 165

 Asp Glu Ile Ile Pro Met Ser Ile Arg Lys Gly Lys Leu Ser Val
                 170                 175                 180

 Gln Gly Glu Val Ser Thr Phe Thr Gly Lys Leu Tyr Ile Glu Phe
                 185                 190                 195

 Val Lys Gly Tyr Tyr Asp Asn Pro Lys Val Cys Ala Leu Tyr Ile
                 200                 205                 210

 Met Ala Gly Thr Val Asp Asp Val Pro Lys Leu Gln Pro His Pro
                 215                 220                 225

 Gly Leu Glu Lys Lys Glu Glu Glu Glu Glu Glu Glu Glu Tyr Asp
                 230                 235                 240

 Glu Gly Ser Asn Leu Lys Lys Gln Thr Asn Lys Asn Arg Val Gln
                 245                 250                 255

 Ser Gly Pro Arg Thr Pro Asn Pro Tyr Ala Ser Asp Asn Ser Ser
                 260                 265                 270

 Leu Met Phe Pro Ile Leu Val Ala Phe Gly Val Phe Ile Pro Thr
                 275                 280                 285

 Leu Phe Cys Leu Cys Arg Leu
                 290

<210> 41
<211> 2693
<212> DNA
<213> Homo sapien

<400> 41
 cgaaaaaaga ggggaagagt attaaagacc atttctggct gggcagggca 50

 ctctcagcag ctcaactgcc cagcgtgacc agtggccacc tctgcagtgt 100

 cttccacaac ctggtcttga ctcgtctgct gaacaaatcc tctgacctca 150

 ggccggctgt gaacgtagtt cctgagagat agcaaacatg cccaacagtg 200

 agcccgcatc tctgctggag ctgttcaaca gcatcgccac acaaggggag 250

 ctcgtaaggt ccctcaaagc gggaaatgcg tcaaaggatg aaattgattc 300

 tgcagtaaag atgttggtgt cattaaaaat gagctacaaa gctgccgcgg 350

 gggaggatta caaggctgac tgtcctccag ggaacccagc acctaccagt 400

 aatcatggcc cagatgccac agaagctgaa gaggattttg tggacccatg 450

 gacagtacag acaagcagtg caaaaggcat agactacgat aagctcattg 500

 ttcggtttgg aagtagtaaa attgacaaag agctaataaa ccgaatagag 550

 agagccaccg gccaaagacc acaccacttc ctgcgcagag gcatcttctt 600

 ctcacacaga gatatgaatc aggttcttga tgcctatgaa aataagaagc 650

 cattttatct gtacacgggc cggggcccct cttctgaagc aatgcatgta 700

 ggtcacctca ttccatttat tttcacaaag tggctccagg atgtatttaa 750

 cgtgcccttg gtcatccaga tgacggatga cgagaagtat ctgtggaagg 800

 acctgaccct ggaccaggcc tatggcgatg ctgttgagaa tgccaaggac 850

 atcatcgcct gtggctttga catcaacaag actttcatat tctctgacct 900

 ggactacatg gggatgagct caggtttcta caaaaatgtg gtgaagattc 950

 aaaagcatgt taccttcaac caagtgaaag gcattttcgg cttcactgac 1000

 agcgactgca ttgggaagat cagttttcct gccatccagg ctgctccctc 1050

 cttcagcaac tcattcccac agatcttccg agacaggacg gatatccagt 1100

 gccttatccc atgtgccatt gaccaggatc cttactttag aatgacaagg 1150

 gacgtcgccc ccaggatcgg ctatcctaaa ccagccctgt tgcactccac 1200

 cttcttccca gccctgcagg gcgcccagac caaaatgagt gccagcgacc 1250

 caaactcctc catcttcctc accgacacgg ccaagcagat caaaaccaag 1300

 gtcaataagc atgcgttttc tggagggaga gacaccatcg aggagcacag 1350

 gcagtttggg ggcaactgtg atgtggacgt gtctttcatg tacctgacct 1400

 tcttcctcga ggacgacgac aagctcgagc agatcaggaa ggattacacc 1450

 agcggagcca tgctcaccgg tgagctcaag aaggcactca tagaggttct 1500

 gcagcccttg atcgcagagc accaggcccg gcgcaaggag gtcacggatg 1550

 agatagtgaa agagttcatg actccccgga agctgtcctt cgactttcag 1600

 tagcactcgt tttacatatg cttataaaag aagtgatgta tcagtaatgt 1650

 atcaataatc ccagcccagt caaagcaccg ccacctgtag gcttctgtct 1700

 catggtaatt actgggcctg gcctctgtaa gcctgtgtat gttatcaata 1750

 ctgtttcttc ctgtgagttc cattatttct atctcttatg ggcaaagcat 1800

 tgtgggtaat tggtgctggc taacattgca tggtcggata gagaagtcca 1850

 gctgtgagtc tctccccaaa gcagccccac agtggagcct tcggctggaa 1900

 gtccatgggc caccctgttc ttgtccatgg aggacttccg agggttccaa 1950

 gtatactctt aagacccact ctgtttaaaa atatatattc tatgtatgcg 2000

 tatatggaat tgaaatgtca ttattgtaac ctagaaagtg ctttgaaata 2050

 ttgatgtggg gaggtttatt gagcacaaga tgtatttcag cccatgcccc 2100

 ctcccaaaaa gaaattgata agtaaaagct tcgttataca tttgactaag 2150

 aaatcaccca gctttaaagc tgcttttaac aatgaagatt gaacagagtt 2200

 cagcaatttt gattaaatta agacttgggg gtgaaacttt ccagtttact 2250

 gaactccaga ccatgcatgt agtccactcc agaaatcatg ctcgcttccc 2300

 ttggcacacc agtgttctcc tgccaaatga ccctagaccc tctgtcctgc 2350

 agagtcaggg tggcttttcc cctgactgtg tccgatgcca aggagtcctg 2400

 gcctccgcag atgcttcatt ttgacccttg gctgcagtgg aagtcagcac 2450

 agagcagtgc cctggctgtg tcctggacgg gtggacttag ctagggagaa 2500

 agtcgaggca gcagccctcg aggccctcac agatgtctag gcaggcctca 2550

 tttcatcacg cagcatgtgc aggcctggaa gagcaaagcc aaatctcagg 2600

 gaagtccttg gttgatgtat ctgggtctcc tctggagcac tctgccctcc 2650

 tgtcacccag tagagtaaat aaacttcctt ggctcctaaa aaa 2693

<210> 42
<211> 471
<212> PRT
<213> Homo sapien

<400> 42
 Met Pro Asn Ser Glu Pro Ala Ser Leu Leu Glu Leu Phe Asn Ser
   1               5                  10                  15

 Ile Ala Thr Gln Gly Glu Leu Val Arg Ser Leu Lys Ala Gly Asn
                  20                  25                  30

 Ala Ser Lys Asp Glu Ile Asp Ser Ala Val Lys Met Leu Val Ser
                  35                  40                  45

 Leu Lys Met Ser Tyr Lys Ala Ala Ala Gly Glu Asp Tyr Lys Ala
                  50                  55                  60

 Asp Cys Pro Pro Gly Asn Pro Ala Pro Thr Ser Asn His Gly Pro
                  65                  70                  75

 Asp Ala Thr Glu Ala Glu Glu Asp Phe Val Asp Pro Trp Thr Val
                  80                  85                  90

 Gln Thr Ser Ser Ala Lys Gly Ile Asp Tyr Asp Lys Leu Ile Val
                  95                 100                 105

 Arg Phe Gly Ser Ser Lys Ile Asp Lys Glu Leu Ile Asn Arg Ile
                 110                 115                 120

 Glu Arg Ala Thr Gly Gln Arg Pro His His Phe Leu Arg Arg Gly
                 125                 130                 135

 Ile Phe Phe Ser His Arg Asp Met Asn Gln Val Leu Asp Ala Tyr
                 140                 145                 150

 Glu Asn Lys Lys Pro Phe Tyr Leu Tyr Thr Gly Arg Gly Pro Ser
                 155                 160                 165

 Ser Glu Ala Met His Val Gly His Leu Ile Pro Phe Ile Phe Thr
                 170                 175                 180

 Lys Trp Leu Gln Asp Val Phe Asn Val Pro Leu Val Ile Gln Met
                 185                 190                 195

 Thr Asp Asp Glu Lys Tyr Leu Trp Lys Asp Leu Thr Leu Asp Gln
                 200                 205                 210

 Ala Tyr Gly Asp Ala Val Glu Asn Ala Lys Asp Ile Ile Ala Cys
                 215                 220                 225

 Gly Phe Asp Ile Asn Lys Thr Phe Ile Phe Ser Asp Leu Asp Tyr
                 230                 235                 240

 Met Gly Met Ser Ser Gly Phe Tyr Lys Asn Val Val Lys Ile Gln
                 245                 250                 255

 Lys His Val Thr Phe Asn Gln Val Lys Gly Ile Phe Gly Phe Thr
                 260                 265                 270

 Asp Ser Asp Cys Ile Gly Lys Ile Ser Phe Pro Ala Ile Gln Ala
                 275                 280                 285

 Ala Pro Ser Phe Ser Asn Ser Phe Pro Gln Ile Phe Arg Asp Arg
                 290                 295                 300

 Thr Asp Ile Gln Cys Leu Ile Pro Cys Ala Ile Asp Gln Asp Pro
                 305                 310                 315

 Tyr Phe Arg Met Thr Arg Asp Val Ala Pro Arg Ile Gly Tyr Pro
                 320                 325                 330

 Lys Pro Ala Leu Leu His Ser Thr Phe Phe Pro Ala Leu Gln Gly
                 335                 340                 345

 Ala Gln Thr Lys Met Ser Ala Ser Asp Pro Asn Ser Ser Ile Phe
                 350                 355                 360

 Leu Thr Asp Thr Ala Lys Gln Ile Lys Thr Lys Val Asn Lys His
                 365                 370                 375

 Ala Phe Ser Gly Gly Arg Asp Thr Ile Glu Glu His Arg Gln Phe
                 380                 385                 390

 Gly Gly Asn Cys Asp Val Asp Val Ser Phe Met Tyr Leu Thr Phe
                 395                 400                 405

 Phe Leu Glu Asp Asp Asp Lys Leu Glu Gln Ile Arg Lys Asp Tyr
                 410                 415                 420

 Thr Ser Gly Ala Met Leu Thr Gly Glu Leu Lys Lys Ala Leu Ile
                 425                 430                 435

 Glu Val Leu Gln Pro Leu Ile Ala Glu His Gln Ala Arg Arg Lys
                 440                 445                 450

 Glu Val Thr Asp Glu Ile Val Lys Glu Phe Met Thr Pro Arg Lys
                 455                 460                 465

 Leu Ser Phe Asp Phe Gln
                 470

<210> 43
<211> 2693
<212> DNA
<213> Homo sapien

<400> 43
 cgaaaaaaga ggggaagagt attaaagacc atttctggct gggcagggca 50

 ctctcagcag ctcaactgcc cagcgtgacc agtggccacc tctgcagtgt 100

 cttccacaac ctggtcttga ctcgtctgct gaacaaatcc tctgacctca 150

 ggccggctgt gaacgtagtt cctgagagat agcaaacatg cccaacagtg 200

 agcccgcatc tctgctggag ctgttcaaca gcatcgccac acaaggggag 250

 ctcgtaaggt ccctcaaagc gggaaatgcg tcaaaggatg aaattgattc 300

 tgcagtaaag atgttggtgt cattaaaaat gagctacaaa gctgccgcgg 350

 gggaggatta caaggctgac tgtcctccag ggaacccagc acctaccagt 400

 aatcatggcc cagatgccac agaagctgaa gaggattttg tggacccatg 450

 gacagtacag acaagcagtg caaaaggcat agactacgat aagctcattg 500

 ttcggtttgg aagtagtaaa attgacaaag agctaataaa ccgaatagag 550

 agagccaccg gccaaagacc acaccacttc ctgcgcagag gcatcttctt 600

 ctcacacaga gatatgaatc aggttcttga tgcctatgaa aataagaagc 650

 cattttatct gtacacgggc cggggcccct cttctgaagc aatgcatgta 700

 ggtcacctca ttccatttat tttcacaaag tggctccagg atgtatttaa 750

 cgtgcccttg gtcatccaga tgacggatga cgagaagtat ctgtggaagg 800

 acctgaccct ggaccaggcc tatggcgatg ctgttgagaa tgccaaggac 850

 atcatcgcct gtggctttga catcaacaag actttcatat tctctgacct 900

 ggactacatg gggatgagct caggtttcta caaaaatgtg gtgaagattc 950

 aaaagcatgt taccttcaac caagtgaaag gcattttcgg cttcactgac 1000

 agcgactgca ttgggaagat cagttttcct gccatccagg ctgctccctc 1050

 cttcagcaac tcattcccac agatcttccg agacaggacg gatatccagt 1100

 gccttatccc atgtgccatt gaccaggatc cttactttag aatgacaagg 1150

 gacgtcgccc ccaggatcgg ctatcctaaa ccagccctgt tgcactccac 1200

 cttcttccca gccctgcagg gcgcccagac caaaatgagt gccagcgacc 1250

 caaactcctc catcttcctc accgacacgg ccaagcagat caaaaccaag 1300

 gtcaataagc atgcgttttc tggagggaga gacaccatcg aggagcacag 1350

 gcagtttggg ggcaactgtg atgtggacgt gtctttcatg tacctgacct 1400

 tcttcctcga ggacgacgac aagctcgagc agatcaggaa ggattacacc 1450

 agcggagcca tgctcaccgg tgagctcaag aaggcactca tagaggttct 1500

 gcagcccttg atcgcagagc accaggcccg gcgcaaggag gtcacggatg 1550

 agatagtgaa agagttcatg actccccgga agctgtcctt cgactttcag 1600

 tagcactcgt tttacatatg cttataaaag aagtgatgta tcagtaatgt 1650

 atcaataatc ccagcccagt caaagcaccg ccacctgtag gcttctgtct 1700

 catggtaatt actgggcctg gcctctgtaa gcctgtgtat gttatcaata 1750

 ctgtttcttc ctgtgagttc cattatttct atctcttatg ggcaaagcat 1800

 tgtgggtaat tggtgctggc taacattgca tggtcggata gagaagtcca 1850

 gctgtgagtc tctccccaaa gcagccccac agtggagcct tcggctggaa 1900

 gtccatgggc caccctgttc ttgtccatgg aggacttccg agggttccaa 1950

 gtatactctt aagacccact ctgtttaaaa atatatattc tatgtatgcg 2000

 tatatggaat tgaaatgtca ttattgtaac ctagaaagtg ctttgaaata 2050

 ttgatgtggg gaggtttatt gagcacaaga tgtatttcag cccatgcccc 2100

 ctcccaaaaa gaaattgata agtaaaagct tcgttataca tttgactaag 2150

 aaatcaccca gctttaaagc tgcttttaac aatgaagatt gaacagagtt 2200

 cagcaatttt gattaaatta agacttgggg gtgaaacttt ccagtttact 2250

 gaactccaga ccatgcatgt agtccactcc agaaatcatg ctcgcttccc 2300

 ttggcacacc agtgttctcc tgccaaatga ccctagaccc tctgtcctgc 2350

 agagtcaggg tggcttttcc cctgactgtg tccgatgcca aggagtcctg 2400

 gcctccgcag atgcttcatt ttgacccttg gctgcagtgg aagtcagcac 2450

 agagcagtgc cctggctgtg tcctggacgg gtggacttag ctagggagaa 2500

 agtcgaggca gcagccctcg aggccctcac agatgtctag gcaggcctca 2550

 tttcatcacg cagcatgtgc aggcctggaa gagcaaagcc aaatctcagg 2600

 gaagtccttg gttgatgtat ctgggtctcc tctggagcac tctgccctcc 2650

 tgtcacccag tagagtaaat aaacttcctt ggctcctaaa aaa 2693

<210> 44
<211> 471
<212> PRT
<213> Homo sapien

<400> 44
 Met Pro Asn Ser Glu Pro Ala Ser Leu Leu Glu Leu Phe Asn Ser
   1               5                  10                  15

 Ile Ala Thr Gln Gly Glu Leu Val Arg Ser Leu Lys Ala Gly Asn
                  20                  25                  30

 Ala Ser Lys Asp Glu Ile Asp Ser Ala Val Lys Met Leu Val Ser
                  35                  40                  45

 Leu Lys Met Ser Tyr Lys Ala Ala Ala Gly Glu Asp Tyr Lys Ala
                  50                  55                  60

 Asp Cys Pro Pro Gly Asn Pro Ala Pro Thr Ser Asn His Gly Pro
                  65                  70                  75

 Asp Ala Thr Glu Ala Glu Glu Asp Phe Val Asp Pro Trp Thr Val
                  80                  85                  90

 Gln Thr Ser Ser Ala Lys Gly Ile Asp Tyr Asp Lys Leu Ile Val
                  95                 100                 105

 Arg Phe Gly Ser Ser Lys Ile Asp Lys Glu Leu Ile Asn Arg Ile
                 110                 115                 120

 Glu Arg Ala Thr Gly Gln Arg Pro His His Phe Leu Arg Arg Gly
                 125                 130                 135

 Ile Phe Phe Ser His Arg Asp Met Asn Gln Val Leu Asp Ala Tyr
                 140                 145                 150

 Glu Asn Lys Lys Pro Phe Tyr Leu Tyr Thr Gly Arg Gly Pro Ser
                 155                 160                 165

 Ser Glu Ala Met His Val Gly His Leu Ile Pro Phe Ile Phe Thr
                 170                 175                 180

 Lys Trp Leu Gln Asp Val Phe Asn Val Pro Leu Val Ile Gln Met
                 185                 190                 195

 Thr Asp Asp Glu Lys Tyr Leu Trp Lys Asp Leu Thr Leu Asp Gln
                 200                 205                 210

 Ala Tyr Gly Asp Ala Val Glu Asn Ala Lys Asp Ile Ile Ala Cys
                 215                 220                 225

 Gly Phe Asp Ile Asn Lys Thr Phe Ile Phe Ser Asp Leu Asp Tyr
                 230                 235                 240

 Met Gly Met Ser Ser Gly Phe Tyr Lys Asn Val Val Lys Ile Gln
                 245                 250                 255

 Lys His Val Thr Phe Asn Gln Val Lys Gly Ile Phe Gly Phe Thr
                 260                 265                 270

 Asp Ser Asp Cys Ile Gly Lys Ile Ser Phe Pro Ala Ile Gln Ala
                 275                 280                 285

 Ala Pro Ser Phe Ser Asn Ser Phe Pro Gln Ile Phe Arg Asp Arg
                 290                 295                 300

 Thr Asp Ile Gln Cys Leu Ile Pro Cys Ala Ile Asp Gln Asp Pro
                 305                 310                 315

 Tyr Phe Arg Met Thr Arg Asp Val Ala Pro Arg Ile Gly Tyr Pro
                 320                 325                 330

 Lys Pro Ala Leu Leu His Ser Thr Phe Phe Pro Ala Leu Gln Gly
                 335                 340                 345

 Ala Gln Thr Lys Met Ser Ala Ser Asp Pro Asn Ser Ser Ile Phe
                 350                 355                 360

 Leu Thr Asp Thr Ala Lys Gln Ile Lys Thr Lys Val Asn Lys His
                 365                 370                 375

 Ala Phe Ser Gly Gly Arg Asp Thr Ile Glu Glu His Arg Gln Phe
                 380                 385                 390

 Gly Gly Asn Cys Asp Val Asp Val Ser Phe Met Tyr Leu Thr Phe
                 395                 400                 405

 Phe Leu Glu Asp Asp Asp Lys Leu Glu Gln Ile Arg Lys Asp Tyr
                 410                 415                 420

 Thr Ser Gly Ala Met Leu Thr Gly Glu Leu Lys Lys Ala Leu Ile
                 425                 430                 435

 Glu Val Leu Gln Pro Leu Ile Ala Glu His Gln Ala Arg Arg Lys
                 440                 445                 450

 Glu Val Thr Asp Glu Ile Val Lys Glu Phe Met Thr Pro Arg Lys
                 455                 460                 465

 Leu Ser Phe Asp Phe Gln
                 470

<210> 45
<211> 3137
<212> DNA
<213> Homo sapien

<400> 45
 gcggagcgtg tgagcagtac tgcggcctcc tctcctctcc taacctcgct 50

 ctcgcggcct acctttaccc gcccgcctgc tcggcgacca gcggggatcc 100

 tcccccagcc gcaagtccac gaagaaagca acgaatgaaa attatgaaga 150

 caacgagaag tcagactcct ccgggtcgcg ctccagctgc ttcggcttcg 200

 tcgcctactc tgtgaactcc ggggagagat ctcgagtcaa gattaagacc 250

 ttaacccacc aacctgcctg ttcggacacc ccccgggccg gccgctgtct 300

 gtccccttct ccatcgccct ctcccagaaa gctccggtgc ttggaccagc 350

 tagagtctga gaaagaggag aggcgcgaac gccactccaa aaagagaagg 400

 gttaaagagg gcaaccctaa cgatacgctt gactttctgt ggctgggaac 450

 accttccacc atgaccacct cagcaagttc ccacttaaat aaaggcatca 500

 agcaggtgta catgtccctg cctcagggtg agaaagtcca ggccatgtat 550

 atctggatcg atggtactgg agaaggactg cgctgcaaga cccggaccct 600

 ggacagtgag cccaagtgtg tggaagagtt gcctgagtgg aatttcgatg 650

 gctccagtac tttacagtct gagggttcca acagtgacat gtatctcgtg 700

 cctgctgcca tgtttcggga ccccttccgt aaggacccta acaagctggt 750

 gttatgtgaa gttttcaagt acaatcgaag gcctgcagag accaatttga 800

 ggcacacctg taaacggata atggacatgg tgagcaacca gcacccctgg 850

 tttggcatgg agcaggagta taccctcatg gggacagatg ggcacccctt 900

 tggttggcct tccaacggct tcccagggcc ccagggtcca tattactgtg 950

 gtgtgggagc agacagagcc tatggcaggg acatcgtgga ggcccattac 1000

 cgggcctgct tgtatgctgg agtcaagatt gcggggacta atgccgaggt 1050

 catgcctgcc cagtgggaat ttcagattgg accttgtgaa ggaatcagca 1100

 tgggagatca tctctgggtg gcccgtttca tcttgcatcg tgtgtgtgaa 1150

 gactttggag tgatagcaac ctttgatcct aagcccattc ctgggaactg 1200

 gaatggtgca ggctgccata ccaacttcag caccaaggcc atgcgggagg 1250

 agaatggtct gaagtacatc gaggaggcca ttgagaaact aagcaagcgg 1300

 caccagtacc acatccgtgc ctatgatccc aagggaggcc tggacaatgc 1350

 ccgacgtcta actggattcc atgaaacctc caacatcaac gacttttctg 1400

 ctggtgtagc caatcgtagc gccagcatac gcattccccg gactgttggc 1450

 caggagaaga agggttactt tgaagatcgt cgcccctctg ccaactgcga 1500

 ccccttttcg gtgacagaag ccctcatccg cacgtgtctt ctcaatgaaa 1550

 ccggcgatga gcccttccag tacaaaaatt aagtggacta gacctccagc 1600

 tgttgagccc ctcctagttc ttcatcccac tccaactctt ccccctctcc 1650

 cagttgtccc gattgtaact caaagggtgg aatatcaagg tcgttttttt 1700

 cattccatgt gcccagttaa tcttgctttc tttgtttggc tgggatagag 1750

 gggtcaagtt attaatttct tcacacctac cctccttttt ttccctatca 1800

 ctgaagcttt ttagtgcatt agtggggagg agggtgggga gacataacca 1850

 ctgcttccat ttaatggggt gcacctgtcc aataggcgta gctatccgga 1900

 cagagcacgt ttgcagaagg gggactcttc ttccaggtag ctgaaagggg 1950

 aagacctgac gtactctggt taggttagga cttgccctcg tggtggaaac 2000

 ttttcttaaa aagttataac caacttttct attaaaagtg ggaattagga 2050

 gagaaggtag gggttgggaa tcagagagaa tggctttggt ctcttgcttg 2100

 tgggactagc ctggcttggg actaaatgcc ctgctctgaa cacgaagctt 2150

 agtataaact gatggatatc cctaccttga aagaagaaaa ggttcttact 2200

 gcttggtcct tgatttatca cacaaagcag aatagtattt ttatatttaa 2250

 atgtaaagac aaaaaactat atgtatggtt ttgtggatta tgtgtgtttt 2300

 gctaaaggaa aaaaccatcc aggtcacggg gcaccaaatt tgagacaaat 2350

 agtcggatta gaaataaagc atctcatttt gagtagagag caagggaagt 2400

 ggttcttaga tggtgatctg ggattaggcc ctcaagaccc ttttgggttt 2450

 ctgccctgcc caccctctgg agaaggtggg cactggatta gttaacagac 2500

 gacacgttac tagcagtcac ttgatctccg tggctttggt ttaaaagaca 2550

 cacttgtcca cataggttta gagataagag ttggctgttc aacttgagca 2600

 tgttactgac agagggggta ttggggttat tttctggtag gaatagcatg 2650

 tcactaaagc aggccttttg atattaaatt ttttaaaaag caaaattata 2700

 gaagtttaga ttttaatcaa atttgtaggg tttctaggta atttttacag 2750

 aattgcttgt ttgcttcaac tgtctcctac ctctgctctt ggaggagatg 2800

 gggacagggc tggagtcaaa acacttgtaa ttttgtatct tgatgtcttt 2850

 gttaagactg ctgaagaatt attttttttc ttttataata aggaataaac 2900

 cccaccttta ttccttcatt tcatctacca ttttctggtt cttgtgttgg 2950

 ctgtggcagg ccagctgtgg ttttcttttg ccatgacaac ttctaattgc 3000

 catgtacagt atgttcaaag tcaaataact cctcattgta aacaaactgt 3050

 gtaactgccc aaagcagcac ttataaatca gcctaacata aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 3137

<210> 46
<211> 373
<212> PRT
<213> Homo sapien

<400> 46
 Met Thr Thr Ser Ala Ser Ser His Leu Asn Lys Gly Ile Lys Gln
   1               5                  10                  15

 Val Tyr Met Ser Leu Pro Gln Gly Glu Lys Val Gln Ala Met Tyr
                  20                  25                  30

 Ile Trp Ile Asp Gly Thr Gly Glu Gly Leu Arg Cys Lys Thr Arg
                  35                  40                  45

 Thr Leu Asp Ser Glu Pro Lys Cys Val Glu Glu Leu Pro Glu Trp
                  50                  55                  60

 Asn Phe Asp Gly Ser Ser Thr Leu Gln Ser Glu Gly Ser Asn Ser
                  65                  70                  75

 Asp Met Tyr Leu Val Pro Ala Ala Met Phe Arg Asp Pro Phe Arg
                  80                  85                  90

 Lys Asp Pro Asn Lys Leu Val Leu Cys Glu Val Phe Lys Tyr Asn
                  95                 100                 105

 Arg Arg Pro Ala Glu Thr Asn Leu Arg His Thr Cys Lys Arg Ile
                 110                 115                 120

 Met Asp Met Val Ser Asn Gln His Pro Trp Phe Gly Met Glu Gln
                 125                 130                 135

 Glu Tyr Thr Leu Met Gly Thr Asp Gly His Pro Phe Gly Trp Pro
                 140                 145                 150

 Ser Asn Gly Phe Pro Gly Pro Gln Gly Pro Tyr Tyr Cys Gly Val
                 155                 160                 165

 Gly Ala Asp Arg Ala Tyr Gly Arg Asp Ile Val Glu Ala His Tyr
                 170                 175                 180

 Arg Ala Cys Leu Tyr Ala Gly Val Lys Ile Ala Gly Thr Asn Ala
                 185                 190                 195

 Glu Val Met Pro Ala Gln Trp Glu Phe Gln Ile Gly Pro Cys Glu
                 200                 205                 210

 Gly Ile Ser Met Gly Asp His Leu Trp Val Ala Arg Phe Ile Leu
                 215                 220                 225

 His Arg Val Cys Glu Asp Phe Gly Val Ile Ala Thr Phe Asp Pro
                 230                 235                 240

 Lys Pro Ile Pro Gly Asn Trp Asn Gly Ala Gly Cys His Thr Asn
                 245                 250                 255

 Phe Ser Thr Lys Ala Met Arg Glu Glu Asn Gly Leu Lys Tyr Ile
                 260                 265                 270

 Glu Glu Ala Ile Glu Lys Leu Ser Lys Arg His Gln Tyr His Ile
                 275                 280                 285

 Arg Ala Tyr Asp Pro Lys Gly Gly Leu Asp Asn Ala Arg Arg Leu
                 290                 295                 300

 Thr Gly Phe His Glu Thr Ser Asn Ile Asn Asp Phe Ser Ala Gly
                 305                 310                 315

 Val Ala Asn Arg Ser Ala Ser Ile Arg Ile Pro Arg Thr Val Gly
                 320                 325                 330

 Gln Glu Lys Lys Gly Tyr Phe Glu Asp Arg Arg Pro Ser Ala Asn
                 335                 340                 345

 Cys Asp Pro Phe Ser Val Thr Glu Ala Leu Ile Arg Thr Cys Leu
                 350                 355                 360

 Leu Asn Glu Thr Gly Asp Glu Pro Phe Gln Tyr Lys Asn
                 365                 370

<210> 47
<211> 1956
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 63
<223> Unknown base

<400> 47
 ccgagcgccc cgcctgctcc gtgtccgaca tgctgcgccg cgctctgctg 50

 tgcctgccgt ggnccgccct ggtgcgcgcc gacgcccccg aggaggagga 100

 ccacgtcttg gtgctgcgga aaagcaactt cgcggaggcg ctggcggccc 150

 acaagtaccc gccggtggag ttccatgccc cctggtgtgg ccactgcaag 200

 gctctggccc ctgagtatgc caaagccgct gggaagctga aggcagaagg 250

 ttccgagatc aggttggcca aggtggacgc cacggaggag tctgacctag 300

 cccagcagta cggcgtgcgc ggctatccca ccatcaagtt cttcaggaat 350

 ggagacacgg cttcccccaa ggaatataca gctggcagag aggctgatga 400

 catcgtgaac tggctgaaga agcgcacggg cccggctgcc accaccctgc 450

 ctgacggcgc agctgcagag tccttggtgg agtccagcga ggtggccgtc 500

 atcggcttct tcaaggacgt ggagtcggac tctgccaagc agtttttgca 550

 ggcagcagag gccatcgatg acataccatt tgggatcact tccaacagtg 600

 acgtgttctc caaataccag ctcgacaaag atggggttgt cctctttaag 650

 aagtttgatg aaggccggaa caactttgaa ggggaggtca ccaaggagaa 700

 cctgctggac tttatcaaac acaaccagct gccccttgtc atcgagttca 750

 ccgagcagac agccccgaag atttttggag gtgaaatcaa gactcacatc 800

 ctgctgttct tgcccaagag tgtgtctgac tatgacggca aactgagcaa 850

 cttcaaaaca gcagccgaga gcttcaaggg caagatcctg ttcatcttca 900

 tcgacagcga ccacaccgac aaccagcgca tcctcgagtt ctttggcctg 950

 aagaaggaag agtgcccggc cgtgcgcctc atcaccttgg aggaggagat 1000

 gaccaagtac aagcccgaat cggaggagct gacggcagag aggatcacag 1050

 agttctgcca ccgcttcctg gagggcaaaa tcaagcccca cctgatgagc 1100

 caggagctgc cggaggactg ggacaagcag cctgtcaagg tgcttgttgg 1150

 gaagaacttt gaagacgtgg cttttgatga gaaaaaaaac gtctttgtgg 1200

 agttctatgc cccatggtgt ggtcactgca aacagttggc tcccatttgg 1250

 gataaactgg gagagacgta caaggaccat gagaacatcg tcatcgccaa 1300

 gatggactcg actgccaacg aggtggaggc cgtcaaagtg cacggcttcc 1350

 ccacactcgg gttctttcct gccagtgccg acaggacggt cattgattac 1400

 aacggggaac gcacgctgga tggttttaag aaattcctag agagcggtgg 1450

 ccaagatggg gcaggggatg ttgacgacct cgaggacctc gaagaagcag 1500

 aggagccaga catggaggaa gacgatgacc agaaagctgt gaaagatgaa 1550

 ctgtaatacg caaagccgga cccgggcgct gccgagaccc ctcgggggct 1600

 gcacacccag cagcagcgca cgcctccgaa gcctgcggcc tcgcttgaag 1650

 gagggcgtcg ccggaaaccc aaggaacctc tctgaagtga cacctcaccc 1700

 ctacacaccg tccgttcacc cccgtctctt ccttctgctt ttcggttttt 1750

 ggaaaacccg gatcctactc taggcagccc accttggtgg gcttgtttcc 1800

 tgaaaccatg atgtactttt tcatacatga gtctgtccag agtgcttgct 1850

 accgtgttcg gagtctcgct gcctccctcc cgcgggaggt tctcctcttt 1900

 ttgaaaattc cgtccgtggg atttttagac atttttacga catcagggta 1950

 tttgtt 1956

<210> 48
<211> 508
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 12
<223> unknown amino acid

<220>
<221> Unsure
<222> 63
<223> Unknown amino acid

<400> 48
 Met Leu Arg Arg Ala Leu Leu Cys Leu Pro Trp Xaa Ala Leu Val
   1               5                  10                  15

 Arg Ala Asp Ala Pro Glu Glu Glu Asp His Val Leu Val Leu Arg
                  20                  25                  30

 Lys Ser Asn Phe Ala Glu Ala Leu Ala Ala His Lys Tyr Pro Pro
                  35                  40                  45

 Val Glu Phe His Ala Pro Trp Cys Gly His Cys Lys Ala Leu Ala
                  50                  55                  60

 Pro Glu Tyr Ala Lys Ala Ala Gly Lys Leu Lys Ala Glu Gly Ser
                  65                  70                  75

 Glu Ile Arg Leu Ala Lys Val Asp Ala Thr Glu Glu Ser Asp Leu
                  80                  85                  90

 Ala Gln Gln Tyr Gly Val Arg Gly Tyr Pro Thr Ile Lys Phe Phe
                  95                 100                 105

 Arg Asn Gly Asp Thr Ala Ser Pro Lys Glu Tyr Thr Ala Gly Arg
                 110                 115                 120

 Glu Ala Asp Asp Ile Val Asn Trp Leu Lys Lys Arg Thr Gly Pro
                 125                 130                 135

 Ala Ala Thr Thr Leu Pro Asp Gly Ala Ala Ala Glu Ser Leu Val
                 140                 145                 150

 Glu Ser Ser Glu Val Ala Val Ile Gly Phe Phe Lys Asp Val Glu
                 155                 160                 165

 Ser Asp Ser Ala Lys Gln Phe Leu Gln Ala Ala Glu Ala Ile Asp
                 170                 175                 180

 Asp Ile Pro Phe Gly Ile Thr Ser Asn Ser Asp Val Phe Ser Lys
                 185                 190                 195

 Tyr Gln Leu Asp Lys Asp Gly Val Val Leu Phe Lys Lys Phe Asp
                 200                 205                 210

 Glu Gly Arg Asn Asn Phe Glu Gly Glu Val Thr Lys Glu Asn Leu
                 215                 220                 225

 Leu Asp Phe Ile Lys His Asn Gln Leu Pro Leu Val Ile Glu Phe
                 230                 235                 240

 Thr Glu Gln Thr Ala Pro Lys Ile Phe Gly Gly Glu Ile Lys Thr
                 245                 250                 255

 His Ile Leu Leu Phe Leu Pro Lys Ser Val Ser Asp Tyr Asp Gly
                 260                 265                 270

 Lys Leu Ser Asn Phe Lys Thr Ala Ala Glu Ser Phe Lys Gly Lys
                 275                 280                 285

 Ile Leu Phe Ile Phe Ile Asp Ser Asp His Thr Asp Asn Gln Arg
                 290                 295                 300

 Ile Leu Glu Phe Phe Gly Leu Lys Lys Glu Glu Cys Pro Ala Val
                 305                 310                 315

 Arg Leu Ile Thr Leu Glu Glu Glu Met Thr Lys Tyr Lys Pro Glu
                 320                 325                 330

 Ser Glu Glu Leu Thr Ala Glu Arg Ile Thr Glu Phe Cys His Arg
                 335                 340                 345

 Phe Leu Glu Gly Lys Ile Lys Pro His Leu Met Ser Gln Glu Leu
                 350                 355                 360

 Pro Glu Asp Trp Asp Lys Gln Pro Val Lys Val Leu Val Gly Lys
                 365                 370                 375

 Asn Phe Glu Asp Val Ala Phe Asp Glu Lys Lys Asn Val Phe Val
                 380                 385                 390

 Glu Phe Tyr Ala Pro Trp Cys Gly His Cys Lys Gln Leu Ala Pro
                 395                 400                 405

 Ile Trp Asp Lys Leu Gly Glu Thr Tyr Lys Asp His Glu Asn Ile
                 410                 415                 420

 Val Ile Ala Lys Met Asp Ser Thr Ala Asn Glu Val Glu Ala Val
                 425                 430                 435

 Lys Val His Gly Phe Pro Thr Leu Gly Phe Phe Pro Ala Ser Ala
                 440                 445                 450

 Asp Arg Thr Val Ile Asp Tyr Asn Gly Glu Arg Thr Leu Asp Gly
                 455                 460                 465

 Phe Lys Lys Phe Leu Glu Ser Gly Gly Gln Asp Gly Ala Gly Asp
                 470                 475                 480

 Val Asp Asp Leu Glu Asp Leu Glu Glu Ala Glu Glu Pro Asp Met
                 485                 490                 495

 Glu Glu Asp Asp Asp Gln Lys Ala Val Lys Asp Glu Leu
                 500                 505

<210> 49
<211> 595
<212> DNA
<213> Homo sapien

<400> 49
 gggcaaggct gggccgggaa gggcgtgggt tgaggagagg ctccagaccc 50

 gcacgccgcg cgcacagagc tctcagcgcc gctcccagcc acagcctccc 100

 gcgcctcgct cagctccaac atggcaaaaa tctccagccc tacagagact 150

 gagcggtgca tcgagtccct gattgctgtc ttccagaagt atgctggaaa 200

 ggatggttat aactacactc tctccaagac agagttccta agcttcatga 250

 atacagaact agctgccttc acaaagaacc agaaggaccc tggtgtcctt 300

 gaccgcatga tgaagaaact ggacaccaac agtgatggtc agctagattt 350

 ctcagaattt cttaatctga ttggtggcct agctatggct tgccatgact 400

 ccttcctcaa ggctgtccct tcccagaagc ggacctgagg accccttggc 450

 cctggccttc aaacccaccc cctttccttc cagcctttct gtcatcatct 500

 ccacagccca cccatcccct gagcacacta accacctcat gcaggcccca 550

 cctgccaata gtaataaagc aatgtcactt ttttaaaaca tgaaa 595

<210> 50
<211> 105
<212> PRT
<213> Homo sapien

<400> 50
 Met Ala Lys Ile Ser Ser Pro Thr Glu Thr Glu Arg Cys Ile Glu
   1               5                  10                  15

 Ser Leu Ile Ala Val Phe Gln Lys Tyr Ala Gly Lys Asp Gly Tyr
                  20                  25                  30

 Asn Tyr Thr Leu Ser Lys Thr Glu Phe Leu Ser Phe Met Asn Thr
                  35                  40                  45

 Glu Leu Ala Ala Phe Thr Lys Asn Gln Lys Asp Pro Gly Val Leu
                  50                  55                  60

 Asp Arg Met Met Lys Lys Leu Asp Thr Asn Ser Asp Gly Gln Leu
                  65                  70                  75

 Asp Phe Ser Glu Phe Leu Asn Leu Ile Gly Gly Leu Ala Met Ala
                  80                  85                  90

 Cys His Asp Ser Phe Leu Lys Ala Val Pro Ser Gln Lys Arg Thr
                  95                 100                 105

<210> 51
<211> 521
<212> DNA
<213> Homo sapien

<400> 51
 tcttcctcgg cgctgcctac ggaggtggca gccatctcct tctcggcatc 50

 atggccgccc tcagacccct tgtgaagccc aagatcgtca aaaagagaac 100

 caagaagttc atccggcacc agtcagaccg atatgtcaaa attaagcgta 150

 actggcggaa acccagaggc attgacaaca gggttcgtag aagattcaag 200

 ggccagatct tgatgcccaa cattggttat ggaagcaaca aaaaaacaaa 250

 gcacatgctg cccagtggct tccggaagtt cctggtccac aacgtcaagg 300

 agctggaagt gctgctgatg tgcaacaaat cttactgtgc cgagatcgct 350

 cacaatgttt cctccaagaa ccgcaaagcc atcgtggaaa gagctgccca 400

 actggccatc agagtcacca accccaatgc caggctgcgc agtgaagaaa 450

 atgagtaggc agctcatgtg cacgttttct gtttaaataa atgtaaaaac 500

 tgccatctgg catcttcctt c 521

<210> 52
<211> 135
<212> PRT
<213> Homo sapien

<400> 52
 Met Ala Ala Leu Arg Pro Leu Val Lys Pro Lys Ile Val Lys Lys
   1               5                  10                  15

 Arg Thr Lys Lys Phe Ile Arg His Gln Ser Asp Arg Tyr Val Lys
                  20                  25                  30

 Ile Lys Arg Asn Trp Arg Lys Pro Arg Gly Ile Asp Asn Arg Val
                  35                  40                  45

 Arg Arg Arg Phe Lys Gly Gln Ile Leu Met Pro Asn Ile Gly Tyr
                  50                  55                  60

 Gly Ser Asn Lys Lys Thr Lys His Met Leu Pro Ser Gly Phe Arg
                  65                  70                  75

 Lys Phe Leu Val His Asn Val Lys Glu Leu Glu Val Leu Leu Met
                  80                  85                  90

 Cys Asn Lys Ser Tyr Cys Ala Glu Ile Ala His Asn Val Ser Ser
                  95                 100                 105

 Lys Asn Arg Lys Ala Ile Val Glu Arg Ala Ala Gln Leu Ala Ile
                 110                 115                 120

 Arg Val Thr Asn Pro Asn Ala Arg Leu Arg Ser Glu Glu Asn Glu
                 125                 130                 135

<210> 53
<211> 1207
<212> DNA
<213> Homo sapien

<400> 53
 gagacagcgc cggggcaagt gagagccgga cgggcactgg gcgactctgt 50

 gcctcgctga ggaaaaataa ctaaacatgg gcaaaggaga tcctaagaag 100

 ccgagaggca aaatgtcatc atatgcattt tttgtgcaaa cttgtcggga 150

 ggagcataag aagaagcacc cagatgcttc agtcaacttc tcagagtttt 200

 ctaagaagtg ctcagagagg tggaagacca tgtctgctaa agagaaagga 250

 aaatttgaag atatggcaaa ggcggacaag gcccgttatg aaagagaaat 300

 gaaaacctat atccctccca aaggggagac aaaaaagaag ttcaaggatc 350

 ccaatgcacc caagaggcct ccttcggcct tcttcctctt ctgctctgag 400

 tatcgcccaa aaatcaaagg agaacatcct ggcctgtcca ttggtgatgt 450

 tgcgaagaaa ctgggagaga tgtggaataa cactgctgca gatgacaagc 500

 agccttatga aaagaaggct gcgaagctga aggaaaaata cgaaaaggat 550

 attgctgcat atcgagctaa aggaaagcct gatgcagcaa aaaagggagt 600

 tgtcaaggct gaaaaaagca agaaaaagaa ggaagaggag gaagatgagg 650

 aagatgaaga ggatgaggag gaggaggaag atgaagaaga tgaagatgaa 700

 gaagaagatg atgatgatga ataagttggt tctagcgcag tttttttttc 750

 ttgtctataa agcatttaac ccccctgtac acaactcact ccttttaaag 800

 aaaaaaattg aaatgtaagg ctgtgtaaga tttgttttta aactgtacag 850

 tgtctttttt tgtatagtta acacactacc gaatgtgtct ttagatagcc 900

 ctgtcctggt ggtattttca atagccacta accttgcctg gtacagtatg 950

 ggggttgtaa attggcatgg aaatttaaag caggttcttg ttggtgcaca 1000

 gcacaaatta gttatatatg gggatggtag ttttttcatc ttcagttgtc 1050

 tctgatgcag cttatacgaa ataattgttg ttctgttaac tgaataccac 1100

 tctgtaattg caaaaaaaaa aaaagttgca gctgttttgt tgacattctg 1150

 aatgcttcta agtaaataca atttttttta ttaaaaaaaa aaaaaaaaaa 1200

 aaaaaaa 1207

<210> 54
<211> 215
<212> PRT
<213> Homo sapien

<400> 54
 Met Gly Lys Gly Asp Pro Lys Lys Pro Arg Gly Lys Met Ser Ser
   1               5                  10                  15

 Tyr Ala Phe Phe Val Gln Thr Cys Arg Glu Glu His Lys Lys Lys
                  20                  25                  30

 His Pro Asp Ala Ser Val Asn Phe Ser Glu Phe Ser Lys Lys Cys
                  35                  40                  45

 Ser Glu Arg Trp Lys Thr Met Ser Ala Lys Glu Lys Gly Lys Phe
                  50                  55                  60

 Glu Asp Met Ala Lys Ala Asp Lys Ala Arg Tyr Glu Arg Glu Met
                  65                  70                  75

 Lys Thr Tyr Ile Pro Pro Lys Gly Glu Thr Lys Lys Lys Phe Lys
                  80                  85                  90

 Asp Pro Asn Ala Pro Lys Arg Pro Pro Ser Ala Phe Phe Leu Phe
                  95                 100                 105

 Cys Ser Glu Tyr Arg Pro Lys Ile Lys Gly Glu His Pro Gly Leu
                 110                 115                 120

 Ser Ile Gly Asp Val Ala Lys Lys Leu Gly Glu Met Trp Asn Asn
                 125                 130                 135

 Thr Ala Ala Asp Asp Lys Gln Pro Tyr Glu Lys Lys Ala Ala Lys
                 140                 145                 150

 Leu Lys Glu Lys Tyr Glu Lys Asp Ile Ala Ala Tyr Arg Ala Lys
                 155                 160                 165

 Gly Lys Pro Asp Ala Ala Lys Lys Gly Val Val Lys Ala Glu Lys
                 170                 175                 180

 Ser Lys Lys Lys Lys Glu Glu Glu Glu Asp Glu Glu Asp Glu Glu
                 185                 190                 195

 Asp Glu Glu Glu Glu Glu Asp Glu Glu Asp Glu Asp Glu Glu Glu
                 200                 205                 210

 Asp Asp Asp Asp Glu
                 215

<210> 55
<211> 4674
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 220-221, 256-257
<223> Unknown base

<400> 55
 cgaggaccgg ggctgtccga gatacggcct tcatatccct cttcctcccc 50

 tggactcttt ctgagctcag agccgccgca gccgggacag gagggcaggc 100

 tttctccaac catcatgctg cggagcatat tacctgtacg ccctggctcc 150

 gggagcggca gtcgagtatc ctctggtcag gcggcgcggg cggcgcctca 200

 gcggaagagc gggcctctgn nggccgcatg tgaccaaccc ccggccccct 250

 cacccnncac gtggttggag gtttccagaa gcgctgccgc caccgcatcg 300

 cgcagctctt tgccgtcgga gcgcttgttt gctgcctcgt actcctccat 350

 ttatccgcca tgataagtgc cagccgagct gcagcagccc gtctcgtggg 400

 cgccgcagcc tcccggggcc ctacggccgc ccgccaccag gatagctgga 450

 atggccttag tcatgaggct tttagacttg tttcaaggcg ggattatgca 500

 tcagaagcaa tcaagggagc agttgttggt attgatttgg gtactaccaa 550

 ctcctgcgtg gcagttatgg aaggtaaaca agcaaaggtg ctggagaatg 600

 ccgaaggtgc cagaaccacc ccttcagttg tggcctttac agcagatggt 650

 gagcgacttg ttggaatgcc ggccaagcga caggctgtca ccaacccaaa 700

 caatacattt tatgctacca agcgtctcat tggccggcga tatgatgatc 750

 ctgaagtaca gaaagacatt aaaaatgttc cctttaaaat tgtccgtgcc 800

 tccaatggtg atgcctgggt tgaggctcat gggaaattgt attctccgag 850

 tcagattgga gcatttgtgt tgatgaagat gaaagagact gcagaaaatt 900

 acttggggca cacagcaaaa aatgctgtga tcacagtccc agcttatttc 950

 aatgactcgc agagacaggc cactaaagat gctggccaga tatctgggac 1000

 tgaatgtgct tcgggtgatt aatgagccca cagctgctgc tcttgcctat 1050

 ggtctagaca aatcagaaga caaagtcatt gctgtatatg atttaggtgg 1100

 tggaactttt gatatttcta tcctggaaat tcagaaagga gtatttgagg 1150

 tgaaatccac aaatggggat accttcttag gtggggaaga ctttgaccag 1200

 gccttgctac ggcacattgt gaaggagttc aagagagaga caggggttga 1250

 tttgactaaa gacaacatgg cacttcagag ggtacgggaa gctgctgaaa 1300

 aggctaaatg tgaactctcc tcatctgtgc agactgacat caatttgccc 1350

 tatcttacaa tggattcttc tggacccaag catttgaata tgaagttgac 1400

 ccgtgctcaa tttgaaggga ttgtcactga tctaatcaga aggactatcg 1450

 ctccatgcca aaaagctatg caagatgcag aagtcagcaa gagtgacata 1500

 ggagaagtga ttcttgtggg tggcatgact aggatgccca aggttcagca 1550

 gactgtacag gatctttttg gcagagcccc aagtaaagct gtcaatcctg 1600

 atgaggctgt ggccattgga gctgccattc agggaggtgt gttggccggc 1650

 gatgtcacgg atgtgctgct ccttgatgtc actcccctgt ctctgggtat 1700

 tgaaactcta ggaggtgtct ttaccaaact tattaatagg aataccacta 1750

 ttccaaccaa gaagagccag gtattctcta ctgccgctga tggtcaaacg 1800

 caagtggaaa ttaaagtgtg tcagggtgaa agagagatgg ctggagacaa 1850

 caaactcctt ggacagttta ctttgattgg aattccacca gcccctcgtg 1900

 gagttcctca gattgaagtt acatttgaca ttgatgccaa tgggatagta 1950

 catgtttctg ctaaagataa aggcacagga cgtgagcagc agattgtaat 2000

 ccagtcttct ggtggattaa gcaaagatga tattgaaaat atggttaaaa 2050

 atgcagagaa atatgctgaa gaagaccggc gaaagaagga acgagttgaa 2100

 gcagttaata tggctgaagg aatcattcac gacacagaaa ccaagatgga 2150

 agaattcaag gaccaattac ctgctgatga gtgcaacaag ctgaaagaag 2200

 agatttccaa aatgagggag ctcctggcta gaaaagacag cgaaacagga 2250

 gaaaatatta gacaggcagc atcctctctt cagcaggcat cattgaagct 2300

 gttcgaaatg gcatacaaaa agatggcatc tgagcgagaa ggctctggaa 2350

 gttctggcac tggggaacaa aaggaagatc aaaaggagga aaaacagtaa 2400

 taatagcaga aattttgaag ccagaaggac aacatatgaa gcttaggagt 2450

 gaagagactt cctgagcaga aatgggcgaa cttcagtctt tttactgtgt 2500

 ttttgcagta ttctatatat aatttcctta atttgtaaat ttagtgacca 2550

 ttagctagtg atcatttaat ggacagtgat tctaacagta taaagttcac 2600

 aatattctat gtccctagcc tgtcattttt cagctgcatg taaaaggagg 2650

 taggatgaat tgatcattat aaagatttaa ctattttatg ctgaagtgac 2700

 catattttca aggggtgaaa ccatctcgca cacagcaatg aaggtagtca 2750

 tccatagact tgaaatgaga ccacatatgg ggatgagatc cttctagtta 2800

 gcctagtact gctgtactgg cctgtatgta catggggtcc ttcaactgag 2850

 gccttgcaag tcaagctggc tgtgccatgt ttgtagatgg ggcagaggaa 2900

 tctagaacaa tgggaaactt agctatttat attaggtaca gctattaaaa 2950

 caaggtagga atgaggctag acctttaact tccctaaggc atacttttct 3000

 agctaccttc tgccctgtgt ctggcaccta catccttgat gattgttctc 3050

 ttacccattc tggaattttt ttttttttaa ataaatacag aaagcatctt 3100

 gatctcttgt ttgtgagggg tgatgccctg agatttagct tcaagaatat 3150

 gccatggctc atgcttccca tatttcccaa agagggaaat acaggatttg 3200

 ctaacactgg ttaaaaatgc aaattcaaga tttggaaggg ctgttataat 3250

 gaaataatga gcagtatcag catgtgcaaa tcttgtttga aggattttat 3300

 tttctcccct tagacctttg gtacatttag aatcttgaaa gtttctagat 3350

 ctctaacatg aaagtttcta gatctctaac atgaaagttt ttagatctct 3400

 aacatgaaaa ccaaggtggc tattttcagg ttgctttcag ctccaagtag 3450

 aaataaccag aattggctta cattaaagaa actgcatcta gaaataagtc 3500

 ctaagatact atttctatgg ctcaaaaata aaaggaaccc agatttcttt 3550

 ccctatttct gcttttctgt cctcagtgta ctggcttgtc ccaaattctc 3600

 tgatgtagtt ctaataatta tcatgtgctg acaacctgag cagaaaggca 3650

 actacatctt tattcaatgt taagatttcc caaaagtctt ccagcacatt 3700

 tcccttatgt ttcatggatg aatgtcatat gccatgttca aaagagtctg 3750

 ttatcaagat gggcttagaa tatcagacac aatggctcct tttataatgt 3800

 tttgtaatat gtagaaatga gattactgta tttccaaaaa tcagtataag 3850

 aaatcaattt aatttgcaag tatgaaggaa gtgatttaga caacattttt 3900

 ggaagattca gtgcttgtta acacccatgt aaaagattct tgggattcgt 3950

 gaaaaattct aggctcaggt ttccaaccac atgaacactc aatgggaaca 4000

 ttgtaggatt atgaaggatt gttatatggt gtgttggaaa ataactttta 4050

 gcatttttgg ttggcccttg cccactgcct ctactgtctc ctaaagataa 4100

 ctttaaaagc cctccaggat ttccaaagta ctccagttga gaactactgg 4150

 cttaatgcta gtcaagattc atccttggga tcagagagag gagccaaatg 4200

 cccaagcaaa atatatattt gagttctatt aggagggaga agttgcttgg 4250

 gtatgggtgg acacagtatt tcagtcacct atcagtaaag ctaatagcat 4300

 aaatagcaag aaggtatatg gagattccct acagccaata ggatatatat 4350

 ctagaataag atttactgta agaaagaaac tggctcacaa ttatggaacc 4400

 gaggtcccac ccacagtcca ctgctgggaa agctgttggg gtaaaatttc 4450

 agtgaccagg aacacagtgg tgtcctagtc cgaggttaga agaatatgga 4500

 tgtcttagct ctggcagttc tatataggcc cttaactgat tagatgatgt 4550

 ccactcacct caaagcagag caatctccaa ttcaatacta atctcttctg 4600

 gagagagaca aatgtttaac ccgttaaatg gcatcaatgg ctaaactgac 4650

 acataaaatt aactatcaca aaag 4674

<210> 56
<211> 799
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 74, 86
<223> unknown amino acid

<220>
<221> Unsure
<222> 220-221, 256-257
<223> Unknown amino acid

<400> 56
 Arg Gly Pro Gly Leu Ser Glu Ile Arg Pro Ser Tyr Pro Ser Ser
   1               5                  10                  15

 Ser Pro Gly Leu Phe Leu Ser Ser Glu Pro Pro Gln Pro Gly Gln
                  20                  25                  30

 Glu Gly Arg Leu Ser Pro Thr Ile Met Leu Arg Ser Ile Leu Pro
                  35                  40                  45

 Val Arg Pro Gly Ser Gly Ser Gly Ser Arg Val Ser Ser Gly Gln
                  50                  55                  60

 Ala Ala Arg Ala Ala Pro Gln Arg Lys Ser Gly Pro Leu Xaa Ala
                  65                  70                  75

 Ala Cys Asp Gln Pro Pro Ala Pro Ser Pro Xaa Thr Trp Leu Glu
                  80                  85                  90

 Val Ser Arg Ser Ala Ala Ala Thr Ala Ser Arg Ser Ser Leu Pro
                  95                 100                 105

 Ser Glu Arg Leu Phe Ala Ala Ser Tyr Ser Ser Ile Tyr Pro Pro
                 110                 115                 120

 Ile Ser Ala Ser Arg Ala Ala Ala Ala Arg Leu Val Gly Ala Ala
                 125                 130                 135

 Ala Ser Arg Gly Pro Thr Ala Ala Arg His Gln Asp Ser Trp Asn
                 140                 145                 150

 Gly Leu Ser His Glu Ala Phe Arg Leu Val Ser Arg Arg Asp Tyr
                 155                 160                 165

 Ala Ser Glu Ala Ile Lys Gly Ala Val Val Gly Ile Asp Leu Gly
                 170                 175                 180

 Thr Thr Asn Ser Cys Val Ala Val Met Glu Gly Lys Gln Ala Lys
                 185                 190                 195

 Val Leu Glu Asn Ala Glu Gly Ala Arg Thr Thr Pro Ser Val Val
                 200                 205                 210

 Ala Phe Thr Ala Asp Gly Glu Arg Leu Val Gly Met Pro Ala Lys
                 215                 220                 225

 Arg Gln Ala Val Thr Asn Pro Asn Asn Thr Phe Tyr Ala Thr Lys
                 230                 235                 240

 Arg Leu Ile Gly Arg Arg Tyr Asp Asp Pro Glu Val Gln Lys Asp
                 245                 250                 255

 Ile Lys Asn Val Pro Phe Lys Ile Val Arg Ala Ser Asn Gly Asp
                 260                 265                 270

 Ala Trp Val Glu Ala His Gly Lys Leu Tyr Ser Pro Ser Gln Ile
                 275                 280                 285

 Gly Ala Phe Val Leu Met Lys Met Lys Glu Thr Ala Glu Asn Tyr
                 290                 295                 300

 Leu Gly His Thr Ala Lys Asn Ala Val Ile Thr Val Pro Ala Tyr
                 305                 310                 315

 Phe Asn Asp Ser Gln Arg Gln Ala Pro Leu Lys Met Leu Ala Arg
                 320                 325                 330

 Tyr Leu Gly Leu Asn Val Leu Arg Val Ile Asn Glu Pro Thr Ala
                 335                 340                 345

 Ala Ala Leu Ala Tyr Gly Leu Asp Lys Ser Glu Asp Lys Val Ile
                 350                 355                 360

 Ala Val Tyr Asp Leu Gly Gly Gly Thr Phe Asp Ile Ser Ile Leu
                 365                 370                 375

 Glu Ile Gln Lys Gly Val Phe Glu Val Lys Ser Thr Asn Gly Asp
                 380                 385                 390

 Thr Phe Leu Gly Gly Glu Asp Phe Asp Gln Ala Leu Leu Arg His
                 395                 400                 405

 Ile Val Lys Glu Phe Lys Arg Glu Thr Gly Val Asp Leu Thr Lys
                 410                 415                 420

 Asp Asn Met Ala Leu Gln Arg Val Arg Glu Ala Ala Glu Lys Ala
                 425                 430                 435

 Lys Cys Glu Leu Ser Ser Ser Val Gln Thr Asp Ile Asn Leu Pro
                 440                 445                 450

 Tyr Leu Thr Met Asp Ser Ser Gly Pro Lys His Leu Asn Met Lys
                 455                 460                 465

 Leu Thr Arg Ala Gln Phe Glu Gly Ile Val Thr Asp Leu Ile Arg
                 470                 475                 480

 Arg Thr Ile Ala Pro Cys Gln Lys Ala Met Gln Asp Ala Glu Val
                 485                 490                 495

 Ser Lys Ser Asp Ile Gly Glu Val Ile Leu Val Gly Gly Met Thr
                 500                 505                 510

 Arg Met Pro Lys Val Gln Gln Thr Val Gln Asp Leu Phe Gly Arg
                 515                 520                 525

 Ala Pro Ser Lys Ala Val Asn Pro Asp Glu Ala Val Ala Ile Gly
                 530                 535                 540

 Ala Ala Ile Gln Gly Gly Val Leu Ala Gly Asp Val Thr Asp Val
                 545                 550                 555

 Leu Leu Leu Asp Val Thr Pro Leu Ser Leu Gly Ile Glu Thr Leu
                 560                 565                 570

 Gly Gly Val Phe Thr Lys Leu Ile Asn Arg Asn Thr Thr Ile Pro
                 575                 580                 585

 Thr Lys Lys Ser Gln Val Phe Ser Thr Ala Ala Asp Gly Gln Thr
                 590                 595                 600

 Gln Val Glu Ile Lys Val Cys Gln Gly Glu Arg Glu Met Ala Gly
                 605                 610                 615

 Asp Asn Lys Leu Leu Gly Gln Phe Thr Leu Ile Gly Ile Pro Pro
                 620                 625                 630

 Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile Asp
                 635                 640                 645

 Ala Asn Gly Ile Val His Val Ser Ala Lys Asp Lys Gly Thr Gly
                 650                 655                 660

 Arg Glu Gln Gln Ile Val Ile Gln Ser Ser Gly Gly Leu Ser Lys
                 665                 670                 675

 Asp Asp Ile Glu Asn Met Val Lys Asn Ala Glu Lys Tyr Ala Glu
                 680                 685                 690

 Glu Asp Arg Arg Lys Lys Glu Arg Val Glu Ala Val Asn Met Ala
                 695                 700                 705

 Glu Gly Ile Ile His Asp Thr Glu Thr Lys Met Glu Glu Phe Lys
                 710                 715                 720

 Asp Gln Leu Pro Ala Asp Glu Cys Asn Lys Leu Lys Glu Glu Ile
                 725                 730                 735

 Ser Lys Met Arg Glu Leu Leu Ala Arg Lys Asp Ser Glu Thr Gly
                 740                 745                 750

 Glu Asn Ile Arg Gln Ala Ala Ser Ser Leu Gln Gln Ala Ser Leu
                 755                 760                 765

 Lys Leu Phe Glu Met Ala Tyr Lys Lys Met Ala Ser Glu Arg Glu
                 770                 775                 780

 Gly Ser Gly Ser Ser Gly Thr Gly Glu Gln Lys Glu Asp Gln Lys
                 785                 790                 795

 Glu Glu Lys Gln


<210> 57
<211> 2852
<212> DNA
<213> Homo sapien

<400> 57
 ggaggtttcc agaagcgctg ccgccaccgc atcgcgcagc tctttgccgt 50

 cggagcgctt gtttgctgcc tcgtactcct ccatttatcc gccatgataa 100

 gtgccagccg agctgcagca gcccgtctcg tgggcgccgc agcctcccgg 150

 ggccctacgg ccgcccgcca ccaggatagc tggaatggcc ttagtcatga 200

 ggcttttaga cttgtttcaa ggcgggatta tgcatcagaa gcaatcaagg 250

 gagcagttgt tggtattgat ttgggtacta ccaactcctg cgtggcagtt 300

 atggaaggta aacaagcaaa ggtgctggag aatgccgaag gtgccagaac 350

 caccccttca gttgtggcct ttacagcaga tggtgagcga cttgttggaa 400

 tgccggccaa gcgacaggct gtcaccaacc caaacaatac attttatgct 450

 accaagcgtc tcattggccg gcgatatgat gatcctgaag tacagaaaga 500

 cattaaaaat gttcccttta aaattgtccg tgcctccaat ggtgatgcct 550

 gggttgaggc tcatgggaaa ttgtattctc cgagtcagat tggagcattt 600

 gtgttgatga agatgaaaga gactgcagaa aattacttgg ggcacacagc 650

 aaaaaatgct gtgatcacag tcccagctta tttcaatgac tcgcagagac 700

 aggccactaa agatgctggc cagatatctg gactgaatgt gcttcgggtg 750

 attaatgagc ccacagctgc tgctcttgcc tatggtctag acaaatcaga 800

 agacaaagtc attgctgtat atgatttagg tggtggaact tttgatattt 850

 ctatcctgga aattcagaaa ggagtatttg aggtgaaatc cacaaatggg 900

 gataccttct taggtgggga agactttgac caggccttgc tacggcacat 950

 tgtgaaggag ttcaagagag agacaggggt tgatttgact aaagacaaca 1000

 tggcacttca gagggtacgg gaagctgctg aaaaggctaa atgtgaactc 1050

 tcctcatctg tgcagactga catcaatttg ccctatctta caatggattc 1100

 ttctggaccc aagcatttga atatgaagtt gacccgtgct caatttgaag 1150

 ggattgtcac tgatctaatc agaaggacta tcgctccatg ccaaaaagct 1200

 atgcaagatg cagaagtcag caagagtgac ataggagaag tgattcttgt 1250

 gggtggcatg actaggatgc ccaaggttca gcagactgta caggatcttt 1300

 ttggcagagc cccaagtaaa gctgtcaatc ctgatgaggc tgtggccatt 1350

 ggagctgcca ttcagggagg tgtgttggcc ggcgatgtca cggatgtgct 1400

 gctccttgat gtcactcccc tgtctctggg tattgaaact ctaggaggtg 1450

 tctttaccaa acttattaat aggaatacca ctattccaac caagaagagc 1500

 caggtattct ctactgccgc tgatggtcaa acgcaagtgg aaattaaagt 1550

 gtgtcagggt gaaagagaga tggctggaga caacaaactc cttggacagt 1600

 ttactttgat tggaattcca ccagcccctc gtggagttcc tcagattgaa 1650

 gttacatttg acattgatgc caatgggata gtacatgttt ctgctaaaga 1700

 taaaggcaca ggacgtgagc agcagattgt aatccagtct tctggtggat 1750

 taagcaaaga tgatattgaa aatatggtta aaaatgcaga gaaatatgct 1800

 gaagaagacc ggcgaaagaa ggaacgagtt gaagcagtta atatggctga 1850

 aggaatcatt cacgacacag aaaccaagat ggaagaattc aaggaccaat 1900

 tacctgctga tgagtgcaac aagctgaaag aagagatttc caaaatgagg 1950

 gagctcctgg ctagaaaaga cagcgaaaca ggagaaaata ttagacaggc 2000

 agcatcctct cttcagcagg catcactgaa gctgttcgaa atggcataca 2050

 aaaagatggc atctgagcga gaaggctctg gaagttctgg cactggggaa 2100

 caaaaggaag atcaaaagga ggaaaaacag taataatagc agaaattttg 2150

 aagccagaag gacaacatat gaagcttagg agtgaagaga cttcctgagc 2200

 agaaatgggc gaacttcagt ctttttactg tgtttttgca gtattctata 2250

 tataatttcc ttaatttgta aatttagtga ccattagcta gtgatcattt 2300

 aatggacagt gattctaaca gtataaagtt cacaatattc tatgtcccta 2350

 gcctgtcatt tttcagctgc atgtaaaagg aggtaggatg aattgatcat 2400

 tataaagatt taactatttt atgctgaagt gaccatattt tcaaggggtg 2450

 aaaccatctc gcacacagca atgaaggtag tcatccatag acttgaaatg 2500

 agaccacata tggggatgag atccttctag ttagcctagt actgctgtac 2550

 tggcctgtat gtacatgggg tccttcaact gaggccttgc aagtcaagct 2600

 ggctgtgcca tgtttgtaga tggggcagag gaatctagaa caatgggaaa 2650

 cttagctatt tatattaggt acagctatta aaacaaggta ggaatgaggc 2700

 tagaccttta acttccctaa ggcatacttt tctagctacc ttctgccctg 2750

 tgtctggcac ctacatcctt gatgattgtt ctcttaccca ttctggaatt 2800

 tttttttttt taaataaata cagaaagcat cttgaaaaaa aaaaaaaaaa 2850

 aa 2852

<210> 58
<211> 679
<212> PRT
<213> Homo sapien

<400> 58
 Met Ile Ser Ala Ser Arg Ala Ala Ala Ala Arg Leu Val Gly Ala
   1               5                  10                  15

 Ala Ala Ser Arg Gly Pro Thr Ala Ala Arg His Gln Asp Ser Trp
                  20                  25                  30

 Asn Gly Leu Ser His Glu Ala Phe Arg Leu Val Ser Arg Arg Asp
                  35                  40                  45

 Tyr Ala Ser Glu Ala Ile Lys Gly Ala Val Val Gly Ile Asp Leu
                  50                  55                  60

 Gly Thr Thr Asn Ser Cys Val Ala Val Met Glu Gly Lys Gln Ala
                  65                  70                  75

 Lys Val Leu Glu Asn Ala Glu Gly Ala Arg Thr Thr Pro Ser Val
                  80                  85                  90

 Val Ala Phe Thr Ala Asp Gly Glu Arg Leu Val Gly Met Pro Ala
                  95                 100                 105

 Lys Arg Gln Ala Val Thr Asn Pro Asn Asn Thr Phe Tyr Ala Thr
                 110                 115                 120

 Lys Arg Leu Ile Gly Arg Arg Tyr Asp Asp Pro Glu Val Gln Lys
                 125                 130                 135

 Asp Ile Lys Asn Val Pro Phe Lys Ile Val Arg Ala Ser Asn Gly
                 140                 145                 150

 Asp Ala Trp Val Glu Ala His Gly Lys Leu Tyr Ser Pro Ser Gln
                 155                 160                 165

 Ile Gly Ala Phe Val Leu Met Lys Met Lys Glu Thr Ala Glu Asn
                 170                 175                 180

 Tyr Leu Gly His Thr Ala Lys Asn Ala Val Ile Thr Val Pro Ala
                 185                 190                 195

 Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp Ala Gly Gln
                 200                 205                 210

 Ile Ser Gly Leu Asn Val Leu Arg Val Ile Asn Glu Pro Thr Ala
                 215                 220                 225

 Ala Ala Leu Ala Tyr Gly Leu Asp Lys Ser Glu Asp Lys Val Ile
                 230                 235                 240

 Ala Val Tyr Asp Leu Gly Gly Gly Thr Phe Asp Ile Ser Ile Leu
                 245                 250                 255

 Glu Ile Gln Lys Gly Val Phe Glu Val Lys Ser Thr Asn Gly Asp
                 260                 265                 270

 Thr Phe Leu Gly Gly Glu Asp Phe Asp Gln Ala Leu Leu Arg His
                 275                 280                 285

 Ile Val Lys Glu Phe Lys Arg Glu Thr Gly Val Asp Leu Thr Lys
                 290                 295                 300

 Asp Asn Met Ala Leu Gln Arg Val Arg Glu Ala Ala Glu Lys Ala
                 305                 310                 315

 Lys Cys Glu Leu Ser Ser Ser Val Gln Thr Asp Ile Asn Leu Pro
                 320                 325                 330

 Tyr Leu Thr Met Asp Ser Ser Gly Pro Lys His Leu Asn Met Lys
                 335                 340                 345

 Leu Thr Arg Ala Gln Phe Glu Gly Ile Val Thr Asp Leu Ile Arg
                 350                 355                 360

 Arg Thr Ile Ala Pro Cys Gln Lys Ala Met Gln Asp Ala Glu Val
                 365                 370                 375

 Ser Lys Ser Asp Ile Gly Glu Val Ile Leu Val Gly Gly Met Thr
                 380                 385                 390

 Arg Met Pro Lys Val Gln Gln Thr Val Gln Asp Leu Phe Gly Arg
                 395                 400                 405

 Ala Pro Ser Lys Ala Val Asn Pro Asp Glu Ala Val Ala Ile Gly
                 410                 415                 420

 Ala Ala Ile Gln Gly Gly Val Leu Ala Gly Asp Val Thr Asp Val
                 425                 430                 435

 Leu Leu Leu Asp Val Thr Pro Leu Ser Leu Gly Ile Glu Thr Leu
                 440                 445                 450

 Gly Gly Val Phe Thr Lys Leu Ile Asn Arg Asn Thr Thr Ile Pro
                 455                 460                 465

 Thr Lys Lys Ser Gln Val Phe Ser Thr Ala Ala Asp Gly Gln Thr
                 470                 475                 480

 Gln Val Glu Ile Lys Val Cys Gln Gly Glu Arg Glu Met Ala Gly
                 485                 490                 495

 Asp Asn Lys Leu Leu Gly Gln Phe Thr Leu Ile Gly Ile Pro Pro
                 500                 505                 510

 Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile Asp
                 515                 520                 525

 Ala Asn Gly Ile Val His Val Ser Ala Lys Asp Lys Gly Thr Gly
                 530                 535                 540

 Arg Glu Gln Gln Ile Val Ile Gln Ser Ser Gly Gly Leu Ser Lys
                 545                 550                 555

 Asp Asp Ile Glu Asn Met Val Lys Asn Ala Glu Lys Tyr Ala Glu
                 560                 565                 570

 Glu Asp Arg Arg Lys Lys Glu Arg Val Glu Ala Val Asn Met Ala
                 575                 580                 585

 Glu Gly Ile Ile His Asp Thr Glu Thr Lys Met Glu Glu Phe Lys
                 590                 595                 600

 Asp Gln Leu Pro Ala Asp Glu Cys Asn Lys Leu Lys Glu Glu Ile
                 605                 610                 615

 Ser Lys Met Arg Glu Leu Leu Ala Arg Lys Asp Ser Glu Thr Gly
                 620                 625                 630

 Glu Asn Ile Arg Gln Ala Ala Ser Ser Leu Gln Gln Ala Ser Leu
                 635                 640                 645

 Lys Leu Phe Glu Met Ala Tyr Lys Lys Met Ala Ser Glu Arg Glu
                 650                 655                 660

 Gly Ser Gly Ser Ser Gly Thr Gly Glu Gln Lys Glu Asp Gln Lys
                 665                 670                 675

 Glu Glu Lys Gln


<210> 59
<211> 2852
<212> DNA
<213> Homo sapien

<400> 59
 ggaggtttcc agaagcgctg ccgccaccgc atcgcgcagc tctttgccgt 50

 cggagcgctt gtttgctgcc tcgtactcct ccatttatcc gccatgataa 100

 gtgccagccg agctgcagca gcccgtctcg tgggcgccgc agcctcccgg 150

 ggccctacgg ccgcccgcca ccaggatagc tggaatggcc ttagtcatga 200

 ggcttttaga cttgtttcaa ggcgggatta tgcatcagaa gcaatcaagg 250

 gagcagttgt tggtattgat ttgggtacta ccaactcctg cgtggcagtt 300

 atggaaggta aacaagcaaa ggtgctggag aatgccgaag gtgccagaac 350

 caccccttca gttgtggcct ttacagcaga tggtgagcga cttgttggaa 400

 tgccggccaa gcgacaggct gtcaccaacc caaacaatac attttatgct 450

 accaagcgtc tcattggccg gcgatatgat gatcctgaag tacagaaaga 500

 cattaaaaat gttcccttta aaattgtccg tgcctccaat ggtgatgcct 550

 gggttgaggc tcatgggaaa ttgtattctc cgagtcagat tggagcattt 600

 gtgttgatga agatgaaaga gactgcagaa aattacttgg ggcacacagc 650

 aaaaaatgct gtgatcacag tcccagctta tttcaatgac tcgcagagac 700

 aggccactaa agatgctggc cagatatctg gactgaatgt gcttcgggtg 750

 attaatgagc ccacagctgc tgctcttgcc tatggtctag acaaatcaga 800

 agacaaagtc attgctgtat atgatttagg tggtggaact tttgatattt 850

 ctatcctgga aattcagaaa ggagtatttg aggtgaaatc cacaaatggg 900

 gataccttct taggtgggga agactttgac caggccttgc tacggcacat 950

 tgtgaaggag ttcaagagag agacaggggt tgatttgact aaagacaaca 1000

 tggcacttca gagggtacgg gaagctgctg aaaaggctaa atgtgaactc 1050

 tcctcatctg tgcagactga catcaatttg ccctatctta caatggattc 1100

 ttctggaccc aagcatttga atatgaagtt gacccgtgct caatttgaag 1150

 ggattgtcac tgatctaatc agaaggacta tcgctccatg ccaaaaagct 1200

 atgcaagatg cagaagtcag caagagtgac ataggagaag tgattcttgt 1250

 gggtggcatg actaggatgc ccaaggttca gcagactgta caggatcttt 1300

 ttggcagagc cccaagtaaa gctgtcaatc ctgatgaggc tgtggccatt 1350

 ggagctgcca ttcagggagg tgtgttggcc ggcgatgtca cggatgtgct 1400

 gctccttgat gtcactcccc tgtctctggg tattgaaact ctaggaggtg 1450

 tctttaccaa acttattaat aggaatacca ctattccaac caagaagagc 1500

 caggtattct ctactgccgc tgatggtcaa acgcaagtgg aaattaaagt 1550

 gtgtcagggt gaaagagaga tggctggaga caacaaactc cttggacagt 1600

 ttactttgat tggaattcca ccagcccctc gtggagttcc tcagattgaa 1650

 gttacatttg acattgatgc caatgggata gtacatgttt ctgctaaaga 1700

 taaaggcaca ggacgtgagc agcagattgt aatccagtct tctggtggat 1750

 taagcaaaga tgatattgaa aatatggtta aaaatgcaga gaaatatgct 1800

 gaagaagacc ggcgaaagaa ggaacgagtt gaagcagtta atatggctga 1850

 aggaatcatt cacgacacag aaaccaagat ggaagaattc aaggaccaat 1900

 tacctgctga tgagtgcaac aagctgaaag aagagatttc caaaatgagg 1950

 gagctcctgg ctagaaaaga cagcgaaaca ggagaaaata ttagacaggc 2000

 agcatcctct cttcagcagg catcactgaa gctgttcgaa atggcataca 2050

 aaaagatggc atctgagcga gaaggctctg gaagttctgg cactggggaa 2100

 caaaaggaag atcaaaagga ggaaaaacag taataatagc agaaattttg 2150

 aagccagaag gacaacatat gaagcttagg agtgaagaga cttcctgagc 2200

 agaaatgggc gaacttcagt ctttttactg tgtttttgca gtattctata 2250

 tataatttcc ttaatttgta aatttagtga ccattagcta gtgatcattt 2300

 aatggacagt gattctaaca gtataaagtt cacaatattc tatgtcccta 2350

 gcctgtcatt tttcagctgc atgtaaaagg aggtaggatg aattgatcat 2400

 tataaagatt taactatttt atgctgaagt gaccatattt tcaaggggtg 2450

 aaaccatctc gcacacagca atgaaggtag tcatccatag acttgaaatg 2500

 agaccacata tggggatgag atccttctag ttagcctagt actgctgtac 2550

 tggcctgtat gtacatgggg tccttcaact gaggccttgc aagtcaagct 2600

 ggctgtgcca tgtttgtaga tggggcagag gaatctagaa caatgggaaa 2650

 cttagctatt tatattaggt acagctatta aaacaaggta ggaatgaggc 2700

 tagaccttta acttccctaa ggcatacttt tctagctacc ttctgccctg 2750

 tgtctggcac ctacatcctt gatgattgtt ctcttaccca ttctggaatt 2800

 tttttttttt taaataaata cagaaagcat cttgaaaaaa aaaaaaaaaa 2850

 aa 2852

<210> 60
<211> 679
<212> PRT
<213> Homo sapien

<400> 60
 Met Ile Ser Ala Ser Arg Ala Ala Ala Ala Arg Leu Val Gly Ala
   1               5                  10                  15

 Ala Ala Ser Arg Gly Pro Thr Ala Ala Arg His Gln Asp Ser Trp
                  20                  25                  30

 Asn Gly Leu Ser His Glu Ala Phe Arg Leu Val Ser Arg Arg Asp
                  35                  40                  45

 Tyr Ala Ser Glu Ala Ile Lys Gly Ala Val Val Gly Ile Asp Leu
                  50                  55                  60

 Gly Thr Thr Asn Ser Cys Val Ala Val Met Glu Gly Lys Gln Ala
                  65                  70                  75

 Lys Val Leu Glu Asn Ala Glu Gly Ala Arg Thr Thr Pro Ser Val
                  80                  85                  90

 Val Ala Phe Thr Ala Asp Gly Glu Arg Leu Val Gly Met Pro Ala
                  95                 100                 105

 Lys Arg Gln Ala Val Thr Asn Pro Asn Asn Thr Phe Tyr Ala Thr
                 110                 115                 120

 Lys Arg Leu Ile Gly Arg Arg Tyr Asp Asp Pro Glu Val Gln Lys
                 125                 130                 135

 Asp Ile Lys Asn Val Pro Phe Lys Ile Val Arg Ala Ser Asn Gly
                 140                 145                 150

 Asp Ala Trp Val Glu Ala His Gly Lys Leu Tyr Ser Pro Ser Gln
                 155                 160                 165

 Ile Gly Ala Phe Val Leu Met Lys Met Lys Glu Thr Ala Glu Asn
                 170                 175                 180

 Tyr Leu Gly His Thr Ala Lys Asn Ala Val Ile Thr Val Pro Ala
                 185                 190                 195

 Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp Ala Gly Gln
                 200                 205                 210

 Ile Ser Gly Leu Asn Val Leu Arg Val Ile Asn Glu Pro Thr Ala
                 215                 220                 225

 Ala Ala Leu Ala Tyr Gly Leu Asp Lys Ser Glu Asp Lys Val Ile
                 230                 235                 240

 Ala Val Tyr Asp Leu Gly Gly Gly Thr Phe Asp Ile Ser Ile Leu
                 245                 250                 255

 Glu Ile Gln Lys Gly Val Phe Glu Val Lys Ser Thr Asn Gly Asp
                 260                 265                 270

 Thr Phe Leu Gly Gly Glu Asp Phe Asp Gln Ala Leu Leu Arg His
                 275                 280                 285

 Ile Val Lys Glu Phe Lys Arg Glu Thr Gly Val Asp Leu Thr Lys
                 290                 295                 300

 Asp Asn Met Ala Leu Gln Arg Val Arg Glu Ala Ala Glu Lys Ala
                 305                 310                 315

 Lys Cys Glu Leu Ser Ser Ser Val Gln Thr Asp Ile Asn Leu Pro
                 320                 325                 330

 Tyr Leu Thr Met Asp Ser Ser Gly Pro Lys His Leu Asn Met Lys
                 335                 340                 345

 Leu Thr Arg Ala Gln Phe Glu Gly Ile Val Thr Asp Leu Ile Arg
                 350                 355                 360

 Arg Thr Ile Ala Pro Cys Gln Lys Ala Met Gln Asp Ala Glu Val
                 365                 370                 375

 Ser Lys Ser Asp Ile Gly Glu Val Ile Leu Val Gly Gly Met Thr
                 380                 385                 390

 Arg Met Pro Lys Val Gln Gln Thr Val Gln Asp Leu Phe Gly Arg
                 395                 400                 405

 Ala Pro Ser Lys Ala Val Asn Pro Asp Glu Ala Val Ala Ile Gly
                 410                 415                 420

 Ala Ala Ile Gln Gly Gly Val Leu Ala Gly Asp Val Thr Asp Val
                 425                 430                 435

 Leu Leu Leu Asp Val Thr Pro Leu Ser Leu Gly Ile Glu Thr Leu
                 440                 445                 450

 Gly Gly Val Phe Thr Lys Leu Ile Asn Arg Asn Thr Thr Ile Pro
                 455                 460                 465

 Thr Lys Lys Ser Gln Val Phe Ser Thr Ala Ala Asp Gly Gln Thr
                 470                 475                 480

 Gln Val Glu Ile Lys Val Cys Gln Gly Glu Arg Glu Met Ala Gly
                 485                 490                 495

 Asp Asn Lys Leu Leu Gly Gln Phe Thr Leu Ile Gly Ile Pro Pro
                 500                 505                 510

 Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile Asp
                 515                 520                 525

 Ala Asn Gly Ile Val His Val Ser Ala Lys Asp Lys Gly Thr Gly
                 530                 535                 540

 Arg Glu Gln Gln Ile Val Ile Gln Ser Ser Gly Gly Leu Ser Lys
                 545                 550                 555

 Asp Asp Ile Glu Asn Met Val Lys Asn Ala Glu Lys Tyr Ala Glu
                 560                 565                 570

 Glu Asp Arg Arg Lys Lys Glu Arg Val Glu Ala Val Asn Met Ala
                 575                 580                 585

 Glu Gly Ile Ile His Asp Thr Glu Thr Lys Met Glu Glu Phe Lys
                 590                 595                 600

 Asp Gln Leu Pro Ala Asp Glu Cys Asn Lys Leu Lys Glu Glu Ile
                 605                 610                 615

 Ser Lys Met Arg Glu Leu Leu Ala Arg Lys Asp Ser Glu Thr Gly
                 620                 625                 630

 Glu Asn Ile Arg Gln Ala Ala Ser Ser Leu Gln Gln Ala Ser Leu
                 635                 640                 645

 Lys Leu Phe Glu Met Ala Tyr Lys Lys Met Ala Ser Glu Arg Glu
                 650                 655                 660

 Gly Ser Gly Ser Ser Gly Thr Gly Glu Gln Lys Glu Asp Gln Lys
                 665                 670                 675

 Glu Glu Lys Gln


<210> 61
<211> 1153
<212> DNA
<213> Homo sapien

<400> 61
 gccgccgccg ccatgaacat tttccggctg actggggacc tgtcccacct 50

 ggcggccatc gtcatcctgc tgctgaagat ctggaagacg cgctcctgcg 100

 ccggtatttc tgggaaaagc cagcttctgt ttgcactggt cttcacaact 150

 cgttacctgg atctttttac ttcatttatt tcattgtata acacatctat 200

 gaaggttatc taccttgcct gctcctatgc cacagtgtac ctgatctacc 250

 tgaaatttaa ggcaacctac gatggaaatc atgatacctt ccgagtggag 300

 tttctggtgg tccctgtggg aggcctctca tttttagtta atcacgattt 350

 ctctcctctt gagatcctct ggaccttctc catctacctg gagtccgtgg 400

 ctatccttcc gcagctgttt atgatcagca agactgggga ggccgagacc 450

 atcaccaccc actacctgtt cttcctgggc ctctatcgtg ctttgtatct 500

 tgtcaactgg atctggcgct tctactttga gggcttcttt gacctcattg 550

 ctgtggtggc cggcgtagtc cagaccatcc tatactgtga cttcttctac 600

 ttgtacatta caaaagtact caagggaaag aagctcagtt tgccagcata 650

 agtgccaaag accatcacca gcatctgtcc ttcagggtgc tcggacagaa 700

 ttcttaccac agcaaaggca taagatgctt gatacggaaa atcagaaact 750

 taactctttt gttgcagata gtcatcagtg gctctgtaaa aacgcagagg 800

 aaaagagcca gaaggtttct gtttaatgca tcttgcctta tcttttttta 850

 ttactgtgta caaagatttt tttacacaaa gaaacttaat gctgtattaa 900

 taaattcagt gtgtagcttc aattgggata gttccaaaag tgaagatttt 950

 gtgaggaata agtgcaaatt ttttttttat tttaaaaaat tctttgaaac 1000

 tcttaagtct ttgtgtctgc aatgaaattg tactccttga cagttgatag 1050

 attatgtatt cttccatccc tcaaacttgc attccactat atttattttt 1100

 tggcaaaaga tgagctgtat ttgtttgaaa tctgagacac tatgttcaat 1150

 tgg 1153

<210> 62
<211> 212
<212> PRT
<213> Homo sapien

<400> 62
 Met Asn Ile Phe Arg Leu Thr Gly Asp Leu Ser His Leu Ala Ala
   1               5                  10                  15

 Ile Val Ile Leu Leu Leu Lys Ile Trp Lys Thr Arg Ser Cys Ala
                  20                  25                  30

 Gly Ile Ser Gly Lys Ser Gln Leu Leu Phe Ala Leu Val Phe Thr
                  35                  40                  45

 Thr Arg Tyr Leu Asp Leu Phe Thr Ser Phe Ile Ser Leu Tyr Asn
                  50                  55                  60

 Thr Ser Met Lys Val Ile Tyr Leu Ala Cys Ser Tyr Ala Thr Val
                  65                  70                  75

 Tyr Leu Ile Tyr Leu Lys Phe Lys Ala Thr Tyr Asp Gly Asn His
                  80                  85                  90

 Asp Thr Phe Arg Val Glu Phe Leu Val Val Pro Val Gly Gly Leu
                  95                 100                 105

 Ser Phe Leu Val Asn His Asp Phe Ser Pro Leu Glu Ile Leu Trp
                 110                 115                 120

 Thr Phe Ser Ile Tyr Leu Glu Ser Val Ala Ile Leu Pro Gln Leu
                 125                 130                 135

 Phe Met Ile Ser Lys Thr Gly Glu Ala Glu Thr Ile Thr Thr His
                 140                 145                 150

 Tyr Leu Phe Phe Leu Gly Leu Tyr Arg Ala Leu Tyr Leu Val Asn
                 155                 160                 165

 Trp Ile Trp Arg Phe Tyr Phe Glu Gly Phe Phe Asp Leu Ile Ala
                 170                 175                 180

 Val Val Ala Gly Val Val Gln Thr Ile Leu Tyr Cys Asp Phe Phe
                 185                 190                 195

 Tyr Leu Tyr Ile Thr Lys Val Leu Lys Gly Lys Lys Leu Ser Leu
                 200                 205                 210

 Pro Ala


<210> 63
<211> 2339
<212> DNA
<213> Homo sapien

<400> 63
 ggtccaccat ggccctgctg cactccggcc gcgtcctccc cgggatcgcc 50

 gccgccttcc acccgggcct cgccgccgcg gcctctgcca gagccagctc 100

 ctggtggacc catgtggaaa tgggacctcc agatcccatt ctgggagtca 150

 ctgaagcctt taagagggac accaatagca aaaagatgaa tctgggagtt 200

 ggtgcctacc gggatgataa tggaaagcct tacgttctgc ctagcgtccg 250

 caaggcagag gcccagattg ccgcaaaaaa tttggacaag gaatacctgc 300

 ccattggggg actggctgaa ttttgcaagg catctgcaga actagccctg 350

 ggtgagaaca gcgaagtctt gaagagtggc cggtttgtca ctgtgcagac 400

 catttctgga actggagcct taaggatcgg agccagtttt ctgcaaagat 450

 tttttaagtt cagccgagat gtctttctgc ccaaaccaac ctggggaaac 500

 cacacaccca tcttcaggga tgctggcatg cagctacaag gttatcggta 550

 ttatgacccc aagacttgcg gttttgactt cacaggcgct gtggaggata 600

 tttcaaaaat accagagcag agtgttcttc ttctgcatgc ctgcgcccac 650

 aatcccacgg gagtggaccc gcgtccggaa cagtggaagg aaatagcaac 700

 agtggtgaag aaaaggaatc tctttgcgtt ctttgacatg gcctaccaag 750

 gctttgccag tggtgatggt gataaggatg cctgggctgt gcgccacttc 800

 atcgaacagg gcattaatgt ttgcctctgc caatcatatg ccaagaacat 850

 gggcttatat ggtgagcgtg taggagcctt cactatggtc tgcaaagatg 900

 cggatgaagc caaaagggta gagtcacagt tgaagatctt gatccgtccc 950

 atgtattcca accctcccct caatggggcc cggattgctg ctgccattct 1000

 gaacacccca gatttgcgaa aacaatggct gcaagaagtg aaaggcatgg 1050

 ctgaccgcat cattggcatg cggactcaac tggtctccaa cctcaagaag 1100

 gagggttcca cccacaattg gcaacacatc accgaccaaa ttggcatgtt 1150

 ctgtttcaca gggctaaagc ctgaacaggt ggagcggctg atcaaggagt 1200

 tctccatcta catgacaaaa gatggccgca tctctgtggc aggggtcacc 1250

 tccagcaacg tgggctacct tgcccatgcc attcaccagg tcaccaagta 1300

 atgtccctgg gtcgaggaaa cagagacaac ctttctgtct tcagcctctg 1350

 ctattgagag cttcacacag acaatgagag agggtggatg gtggtgagtg 1400

 gatcatttct ttcagccaca gtgtgtaaca ctcagcattt gaatgtttct 1450

 cagaaaagaa catgtagtga cacagggcag aggcatccat ggctggcgtc 1500

 tggaatatta aaccaaactc tccccggtcc ttttttctcc aacttttctc 1550

 aaagagttta catgtgcaag aaagtcatcg caccaaaaaa cctgtcaatt 1600

 atgccattgc aatatttcag aagctttaac tgaagtgtca ggttcctcgt 1650

 gagaaacaag cacaccttag aggctttgag agaaggccag ctagttctgt 1700

 catgagtagt cggcctcgtg tctgtcctcc catcttggaa caaccttatc 1750

 aacaggccgc actgcagaaa tgatgtttta tgaaaaccat gagctgctgc 1800

 cactccagca agggaaataa tgcagtttcc tgtcttattt aagaaaaaga 1850

 gaaggctctc ttttctccct tgtcattgcc gttcttttcc ttacacgcaa 1900

 aacattttta actattgcag tttcatccca ttctactgct tgattgacca 1950

 tcaactccat cctatcgaga ttatttaaga atgaagaaca taatttttct 2000

 gctgatgccg taccctcacc cttttcagca aagaatagtg gagagtagga 2050

 aactgtactt tatctcggca tcctcttgaa tgatagtgca agtttctcca 2100

 gttgggatgt tgtctctgcc cggttggacc tcctcccttt gttgaatgtg 2150

 gtgtgcagcc tctcatctca cactgtgagt ccagcggcgc agggtggtac 2200

 caggaaagag gatattctag gcttgcgtgc tgctagctgg gttcaggctt 2250

 cacccactgg aaagaaccac catctgctct aaccatgtag acttattgcg 2300

 gcctggtttt ctctgttaca ataaaattac tgtagaccc 2339

<210> 64
<211> 430
<212> PRT
<213> Homo sapien

<400> 64
 Met Ala Leu Leu His Ser Gly Arg Val Leu Pro Gly Ile Ala Ala
   1               5                  10                  15

 Ala Phe His Pro Gly Leu Ala Ala Ala Ala Ser Ala Arg Ala Ser
                  20                  25                  30

 Ser Trp Trp Thr His Val Glu Met Gly Pro Pro Asp Pro Ile Leu
                  35                  40                  45

 Gly Val Thr Glu Ala Phe Lys Arg Asp Thr Asn Ser Lys Lys Met
                  50                  55                  60

 Asn Leu Gly Val Gly Ala Tyr Arg Asp Asp Asn Gly Lys Pro Tyr
                  65                  70                  75

 Val Leu Pro Ser Val Arg Lys Ala Glu Ala Gln Ile Ala Ala Lys
                  80                  85                  90

 Asn Leu Asp Lys Glu Tyr Leu Pro Ile Gly Gly Leu Ala Glu Phe
                  95                 100                 105

 Cys Lys Ala Ser Ala Glu Leu Ala Leu Gly Glu Asn Ser Glu Val
                 110                 115                 120

 Leu Lys Ser Gly Arg Phe Val Thr Val Gln Thr Ile Ser Gly Thr
                 125                 130                 135

 Gly Ala Leu Arg Ile Gly Ala Ser Phe Leu Gln Arg Phe Phe Lys
                 140                 145                 150

 Phe Ser Arg Asp Val Phe Leu Pro Lys Pro Thr Trp Gly Asn His
                 155                 160                 165

 Thr Pro Ile Phe Arg Asp Ala Gly Met Gln Leu Gln Gly Tyr Arg
                 170                 175                 180

 Tyr Tyr Asp Pro Lys Thr Cys Gly Phe Asp Phe Thr Gly Ala Val
                 185                 190                 195

 Glu Asp Ile Ser Lys Ile Pro Glu Gln Ser Val Leu Leu Leu His
                 200                 205                 210

 Ala Cys Ala His Asn Pro Thr Gly Val Asp Pro Arg Pro Glu Gln
                 215                 220                 225

 Trp Lys Glu Ile Ala Thr Val Val Lys Lys Arg Asn Leu Phe Ala
                 230                 235                 240

 Phe Phe Asp Met Ala Tyr Gln Gly Phe Ala Ser Gly Asp Gly Asp
                 245                 250                 255

 Lys Asp Ala Trp Ala Val Arg His Phe Ile Glu Gln Gly Ile Asn
                 260                 265                 270

 Val Cys Leu Cys Gln Ser Tyr Ala Lys Asn Met Gly Leu Tyr Gly
                 275                 280                 285

 Glu Arg Val Gly Ala Phe Thr Met Val Cys Lys Asp Ala Asp Glu
                 290                 295                 300

 Ala Lys Arg Val Glu Ser Gln Leu Lys Ile Leu Ile Arg Pro Met
                 305                 310                 315

 Tyr Ser Asn Pro Pro Leu Asn Gly Ala Arg Ile Ala Ala Ala Ile
                 320                 325                 330

 Leu Asn Thr Pro Asp Leu Arg Lys Gln Trp Leu Gln Glu Val Lys
                 335                 340                 345

 Gly Met Ala Asp Arg Ile Ile Gly Met Arg Thr Gln Leu Val Ser
                 350                 355                 360

 Asn Leu Lys Lys Glu Gly Ser Thr His Asn Trp Gln His Ile Thr
                 365                 370                 375

 Asp Gln Ile Gly Met Phe Cys Phe Thr Gly Leu Lys Pro Glu Gln
                 380                 385                 390

 Val Glu Arg Leu Ile Lys Glu Phe Ser Ile Tyr Met Thr Lys Asp
                 395                 400                 405

 Gly Arg Ile Ser Val Ala Gly Val Thr Ser Ser Asn Val Gly Tyr
                 410                 415                 420

 Leu Ala His Ala Ile His Gln Val Thr Lys
                 425                 430

<210> 65
<211> 2188
<212> DNA
<213> Homo sapien

<400> 65
 ctctttccct tcggtgtgcc actgaagatc ctggtgtcgc catgggccgc 50

 cgccccgccc gttgttaccg gtattgtaag aacaagccgt acccaaagtc 100

 tcgcttctgc cgaggtgtcc ctgatgccaa gattcgcatt tttgacctgg 150

 ggcggaaaaa ggcaaaagtg gatgagtttc cgctttgtgg ccacatggtg 200

 tcagatgaat atgagcagct gtcctctgaa gccctggagg ctgcccgaat 250

 ttgtgccaat aagtacatgg taaaaagttg tggcaaagat ggcttccata 300

 tccgggtgcg gctccacccc ttccacgtca tccgcatcaa caagatgttg 350

 tcctgtgctg gggctgacag gctccaaaca ggcatgcgag gtgcctttgg 400

 aaagccccag ggcactgtgg ccagggttca cattggccaa gttatcatgt 450

 ccatccgcac caagctgcag aacaaggagc atgtgattga ggccctgcgc 500

 agggccaagt tcaagtttcc tggccgccag aagatccaca tctcaaagaa 550

 gtggggcttc accaagttca atgctgatga atttgaagac atggtggctg 600

 aaaagcggct catcccagat ggctgtgggg tcaagtacat ccccagtcgt 650

 ggccctctgg acaagtggcg ggccctgcac tcatgagggc ttccaatgtg 700

 ctgcccccct cttaatactc accaataaat tctacttcct gtccacctat 750

 gtctttgtat ctacattctt gacggggaag gaacttcctc tgggaacctt 800

 tgggtcattg ccctttcact tcagaaacag gttgacaact cagccctgct 850

 catgaggcag caaaccctgc aaagggctgg gactggtggc cttatgtcag 900

 ttgtctactc tggagcttga cttggacctc cccaggtcct aggcagtagg 950

 ttgaaaaaca ctgaagtgct tttcatgaag cacagctgca gcaaagcctt 1000

 gcaatcccag gctggggtca gcctacagtt gtgttgctta ttacaacaca 1050

 tgcggaccaa gaggggcttg tgggctagag gctgaccagc agcgtttatt 1100

 tagcaagggt aggtgtgcat cacattgggc ttgttctcac ccatctggtt 1150

 tggccattcc tccttggtgg gaatcatcca ggtactgctg aggtcacctg 1200

 cgatttgccc catttcctat ctctagcaac ctcctgggcc ccatgccccc 1250

 accccttcta gaacctgcat tcccagggcc ttcaccacct gaccaaaggt 1300

 ctaggctaac ctttggtcat ttgtaacaag acctcggaac agacacgtgt 1350

 gtggcatggt ttggcctggg gatcttagat gtctgacctg aactattgta 1400

 gaacagcgct ggcttttggg ggagcagcaa aaatgagagg agtgctaggt 1450

 gggtggcctg agcatctgta tccagggaca ggactccaaa ggcttttggt 1500

 cccagagctg gggtatgttg gccccagccc ccagcctgtg gctcccaaaa 1550

 ggcctctggt tttttgtaat ctcagtttac agccatttct taggttttta 1600

 attaccttta ttttattttg ccaaacatac ctgggaatac cttttatttt 1650

 ttttttacct tggggtgatg gttccaaacc ataaatgtga ttatagttaa 1700

 cacatgaccc ttctagcgtc ccagccagtg tttttcctga cctctcttct 1750

 ttggagagga ggatggaagg gaggggtccg gcatgctgct ggcattttgc 1800

 tgtgtcctgc agcccctttc cgggacacct gggttcacac agctttttag 1850

 cttacataac tggtgcagat tttctgtgtg gagatgttgc cttgaccagc 1900

 cttggctgga ctttaccagg catgcagaag cctgtaccaa cacagactac 1950

 agcacccagg aggtgcgagt gtggctgctc agcggttata acaggcctga 2000

 ctgcattgtt caccggatta taatgagcca aaatgtttcc cggtgtttgc 2050

 tggtttcagg gaaggagttt gatatagcag attaaccacc ctccttgtag 2100

 ctattggggc ttaatggttt cctggtgatt cttaccaatc cacaataaac 2150

 atggcccatt ggcatatctg caaaaaaaaa aaaaaaaa 2188

<210> 66
<211> 214
<212> PRT
<213> Homo sapien

<400> 66
 Met Gly Arg Arg Pro Ala Arg Cys Tyr Arg Tyr Cys Lys Asn Lys
   1               5                  10                  15

 Pro Tyr Pro Lys Ser Arg Phe Cys Arg Gly Val Pro Asp Ala Lys
                  20                  25                  30

 Ile Arg Ile Phe Asp Leu Gly Arg Lys Lys Ala Lys Val Asp Glu
                  35                  40                  45

 Phe Pro Leu Cys Gly His Met Val Ser Asp Glu Tyr Glu Gln Leu
                  50                  55                  60

 Ser Ser Glu Ala Leu Glu Ala Ala Arg Ile Cys Ala Asn Lys Tyr
                  65                  70                  75

 Met Val Lys Ser Cys Gly Lys Asp Gly Phe His Ile Arg Val Arg
                  80                  85                  90

 Leu His Pro Phe His Val Ile Arg Ile Asn Lys Met Leu Ser Cys
                  95                 100                 105

 Ala Gly Ala Asp Arg Leu Gln Thr Gly Met Arg Gly Ala Phe Gly
                 110                 115                 120

 Lys Pro Gln Gly Thr Val Ala Arg Val His Ile Gly Gln Val Ile
                 125                 130                 135

 Met Ser Ile Arg Thr Lys Leu Gln Asn Lys Glu His Val Ile Glu
                 140                 145                 150

 Ala Leu Arg Arg Ala Lys Phe Lys Phe Pro Gly Arg Gln Lys Ile
                 155                 160                 165

 His Ile Ser Lys Lys Trp Gly Phe Thr Lys Phe Asn Ala Asp Glu
                 170                 175                 180

 Phe Glu Asp Met Val Ala Glu Lys Arg Leu Ile Pro Asp Gly Cys
                 185                 190                 195

 Gly Val Lys Tyr Ile Pro Ser Arg Gly Pro Leu Asp Lys Trp Arg
                 200                 205                 210

 Ala Leu His Ser


<210> 67
<211> 344
<212> DNA
<213> Homo sapien

<400> 67
 cctttccggc ggtgacgacc tacgcacacg agaacatgcc tctcgcaaag 50

 gatctccttc atccctctcc agaagaggag aagaggaaac acaagaagaa 100

 acgcctggtg cagagcccca attcctactt catggatgtg aaatgcccag 150

 gatgctataa aatcaccacg gtctttagcc atgcacaaac ggtagttttg 200

 tgtgttggct gctccactgt cctctgccag cctacaggag gaaaagcaag 250

 gcttacagaa ggatgttcct tcaggaggaa gcagcactaa aagcactctg 300

 agtcaagatg agtgggaaac catctcaata aacacatttt ggat 344

<210> 68
<211> 84
<212> PRT
<213> Homo sapien

<400> 68
 Met Pro Leu Ala Lys Asp Leu Leu His Pro Ser Pro Glu Glu Glu
   1               5                  10                  15

 Lys Arg Lys His Lys Lys Lys Arg Leu Val Gln Ser Pro Asn Ser
                  20                  25                  30

 Tyr Phe Met Asp Val Lys Cys Pro Gly Cys Tyr Lys Ile Thr Thr
                  35                  40                  45

 Val Phe Ser His Ala Gln Thr Val Val Leu Cys Val Gly Cys Ser
                  50                  55                  60

 Thr Val Leu Cys Gln Pro Thr Gly Gly Lys Ala Arg Leu Thr Glu
                  65                  70                  75

 Gly Cys Ser Phe Arg Arg Lys Gln His
                  80

<210> 69
<211> 3502
<212> DNA
<213> Homo sapien

<400> 69
 acatgacagc agatccgcgg aagggcagaa tgggactcca agcctgcctc 50

 ctagggctct ttgccctcat cctctctggc aaatgcagtt acagcccgga 100

 gcccgaccag cggaggacgc tgcccccagg ctgggtgtcc ctgggccgtg 150

 cggaccctga ggaagagctg agtctcacct ttgccctgag acagcagaat 200

 gtggaaagac tctcggagct ggtgcaggct gtgtcggatc ccagctctcc 250

 tcaatacgga aaatacctga ccctagagaa tgtggctgat ctggtgaggc 300

 catccccact gaccctccac acggtgcaaa aatggctctt ggcagccgga 350

 gcccagaagt gccattctgt gatcacacag gactttctga cttgctggct 400

 gagcatccga caagcagagc tgctgctccc tggggctgag tttcatcact 450

 atgtgggagg acctacggaa acccatgttg taaggtcccc acatccctac 500

 cagcttccac aggccttggc cccccatgtg gactttgtgg ggggactgca 550

 ccgttttccc ccaacatcat ccctgaggca acgtcctgag ccgcaggtga 600

 cagggactgt aggcctgcat ctgggggtaa ccccctctgt gatccgtaag 650

 cgatacaact tgacctcaca agacgtgggc tctggcacca gcaataacag 700

 ccaagcctgt gcccagttcc tggagcagta tttccatgac tcagacctgg 750

 ctcagttcat gcgcctcttc ggtggcaact ttgcacatca ggcatcagta 800

 gcccgtgtgg ttggacaaca gggccggggc cgggccggga ttgaggccag 850

 tctagatgtg cagtacctga tgagtgctgg tgccaacatc tccacctggg 900

 tctacagtag ccctggccgg catgagggac aggagccctt cctgcagtgg 950

 ctcatgctgc tcagtaatga gtcagccctg ccacatgtgc atactgtgag 1000

 ctatggagat gatgaggact ccctcagcag cgcctacatc cagcgggtca 1050

 acactgagct catgaaggct gccgctcggg gtctcaccct gctcttcgcc 1100

 tcaggtgaca gtggggccgg gtgttggtct gtctctggaa gacaccagtt 1150

 ccgccctacc ttccctgcct ccagccccta tgtcaccaca gtgggaggca 1200

 catccttcca ggaacctttc ctcatcacaa atgaaattgt tgactatatc 1250

 agtggtggtg gcttcagcaa tgtgttccca cggccttcat accaggagga 1300

 agctgtaacg aagttcctga gctctagccc ccacctgcca ccatccagtt 1350

 acttcaatgc cagtggccgt gcctacccag atgtggctgc actttctgat 1400

 ggctactggg tggtcagcaa cagagtgccc attccatggg tgtccggaac 1450

 ctcggcctct actccagtgt ttggggggat cctatccttg atcaatgagc 1500

 acaggatcct tagtggccgc ccccctcttg gctttctcaa cccaaggctc 1550

 taccagcagc atggggcagg actctttgat gtaacccgtg gctgccatga 1600

 gtcctgtctg gatgaagagg tagagggcca gggtttctgc tctggtcctg 1650

 gctgggatcc tgtaacaggc tggggaacac ccaacttccc agctttgctg 1700

 aagactctac tcaacccctg accctttcct atcaggagag atggcttgtc 1750

 ccctgccctg aagctggcag ttcagtccct tattctgccc tgttggaagc 1800

 cctgctgaac cctcaactat tgactgctgc agacagctta tctccctaac 1850

 cctgaaatgc ggtgagcttg acttgactcc caaccctacc atgctccatc 1900

 atactcaggt ctccctactc ctgccttaga ttcctcaata agatgctgta 1950

 actagcattt tttgaatgcc tctccctccg catctcatct ttctcttttc 2000

 aatcaggctt ttccaaaggg ttgtatacag actctgtgca ctatttcact 2050

 tgatattcat tccccaattc actgcaagga gacctctact gtcaccgttt 2100

 actctttcct accctgacat ccagaaacaa tggcctccag tgcatacttc 2150

 tcaatctttg ctttatggcc tttccatcat agttgcccac tccctctcct 2200

 tacttagctt ccaggtctta acttctctga ctactcttgt cttcctctct 2250

 catcaatttc tgcttcttca tggaatgctg accttcattg ctccatttgt 2300

 agatttttgc tcttctcagt ttactcattg tcccctggaa caaatcactg 2350

 acatctacaa ccattaccat ctcactaaat aagactttct atccaataat 2400

 gattgatacc tcaaatgtaa gatgcgtgat actcaacatt tcatcgtcca 2450

 ccttcccaac cccaaacaat tccatctcgt ttcttcttgg taaatgatgc 2500

 tatgcttttt ccaaccaagc cagaaacctg tgtcatcttt tcaccccacc 2550

 ttcaatcaac aagtcctcaa tcaacaagtc ctactgactg cacatcttaa 2600

 atatatcttt atcagtccac aagtccttcc aattatattt cccaagtata 2650

 tctagaactt atccacttat atccccactg ctactacctt agtttagggc 2700

 tatattctct tgaaaaaaag tgtccttact tcctgccaat ccccaagtca 2750

 tcttccagag taaaatgcaa atcccatcag gccacttgga tgaaaaccct 2800

 tcaaggatta ctggatagaa ttcaggcttt cccctccagc ccccaatcat 2850

 agctcacaaa ccttccttgc tatttgttct taagtaaaaa atcatttttc 2900

 ctcctccctc cccaaacccc aaggaactct cactcttgct caagctgttc 2950

 cgtcccctta ccacccctga tacaactgcc aggttaattt ccagaattct 3000

 tgcaagactc agttcagaag tcaccttctt tcgtgaatgt tttgattccc 3050

 tgaggctact ttattttggt atggctgaaa aatcctagat tttctaaaca 3100

 aaacctgttt gaatcttggt tctgatatgg actaggagag agactgggtc 3150

 aagtaagctt atctccctga ggctgtttcc tcgtctgtta agtgtgaata 3200

 tcaatacctg cctttcataa tcaccaggga ataaagtgga ataatgttga 3250

 taacagtgct tggcacctgg aagtaggtgg cagatgttaa cgcccttcct 3300

 cccttgcact gcgccccctg tgcctacctc tagcattgta acgaccacat 3350

 agtattgaaa tggccagttt acttgtctgc cttcctttcc aagaccgttg 3400

 gtgcctagag gactagaatc gtgtcctatt taactttgtg ttcccaggtc 3450

 ctagctcagg agttggcaaa taagaattaa atgtctgcta caccgaaaca 3500

 aa 3502

<210> 70
<211> 563
<212> PRT
<213> Homo sapien

<400> 70
 Met Gly Leu Gln Ala Cys Leu Leu Gly Leu Phe Ala Leu Ile Leu
   1               5                  10                  15

 Ser Gly Lys Cys Ser Tyr Ser Pro Glu Pro Asp Gln Arg Arg Thr
                  20                  25                  30

 Leu Pro Pro Gly Trp Val Ser Leu Gly Arg Ala Asp Pro Glu Glu
                  35                  40                  45

 Glu Leu Ser Leu Thr Phe Ala Leu Arg Gln Gln Asn Val Glu Arg
                  50                  55                  60

 Leu Ser Glu Leu Val Gln Ala Val Ser Asp Pro Ser Ser Pro Gln
                  65                  70                  75

 Tyr Gly Lys Tyr Leu Thr Leu Glu Asn Val Ala Asp Leu Val Arg
                  80                  85                  90

 Pro Ser Pro Leu Thr Leu His Thr Val Gln Lys Trp Leu Leu Ala
                  95                 100                 105

 Ala Gly Ala Gln Lys Cys His Ser Val Ile Thr Gln Asp Phe Leu
                 110                 115                 120

 Thr Cys Trp Leu Ser Ile Arg Gln Ala Glu Leu Leu Leu Pro Gly
                 125                 130                 135

 Ala Glu Phe His His Tyr Val Gly Gly Pro Thr Glu Thr His Val
                 140                 145                 150

 Val Arg Ser Pro His Pro Tyr Gln Leu Pro Gln Ala Leu Ala Pro
                 155                 160                 165

 His Val Asp Phe Val Gly Gly Leu His Arg Phe Pro Pro Thr Ser
                 170                 175                 180

 Ser Leu Arg Gln Arg Pro Glu Pro Gln Val Thr Gly Thr Val Gly
                 185                 190                 195

 Leu His Leu Gly Val Thr Pro Ser Val Ile Arg Lys Arg Tyr Asn
                 200                 205                 210

 Leu Thr Ser Gln Asp Val Gly Ser Gly Thr Ser Asn Asn Ser Gln
                 215                 220                 225

 Ala Cys Ala Gln Phe Leu Glu Gln Tyr Phe His Asp Ser Asp Leu
                 230                 235                 240

 Ala Gln Phe Met Arg Leu Phe Gly Gly Asn Phe Ala His Gln Ala
                 245                 250                 255

 Ser Val Ala Arg Val Val Gly Gln Gln Gly Arg Gly Arg Ala Gly
                 260                 265                 270

 Ile Glu Ala Ser Leu Asp Val Gln Tyr Leu Met Ser Ala Gly Ala
                 275                 280                 285

 Asn Ile Ser Thr Trp Val Tyr Ser Ser Pro Gly Arg His Glu Gly
                 290                 295                 300

 Gln Glu Pro Phe Leu Gln Trp Leu Met Leu Leu Ser Asn Glu Ser
                 305                 310                 315

 Ala Leu Pro His Val His Thr Val Ser Tyr Gly Asp Asp Glu Asp
                 320                 325                 330

 Ser Leu Ser Ser Ala Tyr Ile Gln Arg Val Asn Thr Glu Leu Met
                 335                 340                 345

 Lys Ala Ala Ala Arg Gly Leu Thr Leu Leu Phe Ala Ser Gly Asp
                 350                 355                 360

 Ser Gly Ala Gly Cys Trp Ser Val Ser Gly Arg His Gln Phe Arg
                 365                 370                 375

 Pro Thr Phe Pro Ala Ser Ser Pro Tyr Val Thr Thr Val Gly Gly
                 380                 385                 390

 Thr Ser Phe Gln Glu Pro Phe Leu Ile Thr Asn Glu Ile Val Asp
                 395                 400                 405

 Tyr Ile Ser Gly Gly Gly Phe Ser Asn Val Phe Pro Arg Pro Ser
                 410                 415                 420

 Tyr Gln Glu Glu Ala Val Thr Lys Phe Leu Ser Ser Ser Pro His
                 425                 430                 435

 Leu Pro Pro Ser Ser Tyr Phe Asn Ala Ser Gly Arg Ala Tyr Pro
                 440                 445                 450

 Asp Val Ala Ala Leu Ser Asp Gly Tyr Trp Val Val Ser Asn Arg
                 455                 460                 465

 Val Pro Ile Pro Trp Val Ser Gly Thr Ser Ala Ser Thr Pro Val
                 470                 475                 480

 Phe Gly Gly Ile Leu Ser Leu Ile Asn Glu His Arg Ile Leu Ser
                 485                 490                 495

 Gly Arg Pro Pro Leu Gly Phe Leu Asn Pro Arg Leu Tyr Gln Gln
                 500                 505                 510

 His Gly Ala Gly Leu Phe Asp Val Thr Arg Gly Cys His Glu Ser
                 515                 520                 525

 Cys Leu Asp Glu Glu Val Glu Gly Gln Gly Phe Cys Ser Gly Pro
                 530                 535                 540

 Gly Trp Asp Pro Val Thr Gly Trp Gly Thr Pro Asn Phe Pro Ala
                 545                 550                 555

 Leu Leu Lys Thr Leu Leu Asn Pro
                 560

<210> 71
<211> 801
<212> DNA
<213> Homo sapien

<400> 71
 caccgcaccc tcggactgcc ccaaggcccc cgccgccgct ccagcgccgc 50

 gcagccaccg ccgccgccgc cgcctctcct tagtcgccgc catgacgacc 100

 gcgtccacct cgcaggtgcg ccagaactac caccaggact cagaggccgc 150

 catcaaccgc cagatcaacc tggagctcta cgcctcctac gtttacctgt 200

 ccatgtctta ctactttgac cgcgatgatg tggctttgaa gaactttgcc 250

 aaatactttc ttcaccaatc tcatgaggag agggaacatg ctgagaaact 300

 gatgaagctg cagaaccaac gaggtggccg aatcttcctt caggatatca 350

 agaaaccaga ctgtgatgac tgggagagcg ggctgaatgc aatggagtgt 400

 gcattacatt tggaaaaaaa tgtgaatcag tcactactgg aactgcacaa 450

 actggccact gacaaaaatg acccccattt gtgtgacttc attgagacac 500

 attacctgaa tgagcaggtg aaagccatca aagaattggg tgaccacgtg 550

 accaacttgc gcaagatggg agcgcccgaa tctggcttgg cggaatatct 600

 ctttgacaag cacacctggg agacagtgat aatgaaagct aagcctcggg 650

 ctaatttccc atagccgtgg ggtgacttcc tggtcaccaa ggcagtgcat 700

 gcatgttggg gtttccttta ccttttctat aagttgtacc aaaacatcca 750

 cttaagttct ttgatttgta ccattccttc aaataaagaa atttggtacc 800

 c 801

<210> 72
<211> 190
<212> PRT
<213> Homo sapien

<400> 72
 Met Thr Thr Ala Ser Thr Ser Gln Val Arg Gln Asn Tyr His Gln
   1               5                  10                  15

 Asp Ser Glu Ala Ala Ile Asn Arg Gln Ile Asn Leu Glu Leu Tyr
                  20                  25                  30

 Ala Ser Tyr Val Tyr Leu Ser Met Ser Tyr Tyr Phe Asp Arg Asp
                  35                  40                  45

 Asp Val Ala Leu Lys Asn Phe Ala Lys Tyr Phe Leu His Gln Ser
                  50                  55                  60

 His Glu Glu Arg Glu His Ala Glu Lys Leu Met Lys Leu Gln Asn
                  65                  70                  75

 Gln Arg Gly Gly Arg Ile Phe Leu Gln Asp Ile Lys Lys Pro Asp
                  80                  85                  90

 Cys Asp Asp Trp Glu Ser Gly Leu Asn Ala Met Glu Cys Ala Leu
                  95                 100                 105

 His Leu Glu Lys Asn Val Asn Gln Ser Leu Leu Glu Leu His Lys
                 110                 115                 120

 Leu Ala Thr Asp Lys Asn Asp Pro His Leu Cys Asp Phe Ile Glu
                 125                 130                 135

 Thr His Tyr Leu Asn Glu Gln Val Lys Ala Ile Lys Glu Leu Gly
                 140                 145                 150

 Asp His Val Thr Asn Leu Arg Lys Met Gly Ala Pro Glu Ser Gly
                 155                 160                 165

 Leu Ala Glu Tyr Leu Phe Asp Lys His Thr Trp Glu Thr Val Ile
                 170                 175                 180

 Met Lys Ala Lys Pro Arg Ala Asn Phe Pro
                 185                 190

<210> 73
<211> 2826
<212> DNA
<213> Homo sapien

<400> 73
 gggcggctga gtaggtgggt ggtgcgggcc cggccgggcc ggggcaggag 50

 acgggcgtgg ggtcggcgct agcccccgag aacccccgtt tcatcctccg 100

 ctctcatccc cgtcccggtc ccagtcccgt tcccatccct acacctccgt 150

 ccgccgttcc ccgggccccg ccgccccgga tgccgagccc gcccgccgtc 200

 ttcccgctcc caggcctggc cgccatggcg ccgcgggcgg gaggcctttg 250

 tggggcgggc acgtggggcg ctgggggcgc gggagcgggg ccgccatggg 300

 ctgcggggcc gcgcgagcgc tcgcctccgt cctctgcctc cgcaggaacg 350

 ccgcgatggc tgcgcaggga gagccccagg tccagttcaa acttgtattg 400

 gttggtgatg gtggtactgg aaaaacgacc ttcgtgaaac gtcatttgac 450

 tggtgaattt gagaagaagt atgtagccac cttgggtgtt gaggttcatc 500

 ccctagtgtt ccacaccaac agaggaccta ttaagttcaa tgtatgggac 550

 acagccggcc aggagaaatt cggtggactg agagatggct attatatcca 600

 agcccagtgt gccatcataa tgtttgatgt aacatcgaga gttacttaca 650

 agaatgtgcc taactggcat agagatctgg tacgagtgtg tgaaaacatc 700

 cccattgtgt tgtgtggcaa caaagtggat attaaggaca ggaaagtgaa 750

 ggcgaaatcc attgtcttcc accgaaagaa gaatcttcag tactacgaca 800

 tttctgccaa aagtaactac aactttgaaa agcccttcct ctggcttgct 850

 aggaagctca ttggagaccc taacttggaa tttgttgcca tgcctgctct 900

 cgccccacca gaagttgtca tggacccagc tttggcagca cagtatgagc 950

 acgacttaga ggttgctcag acaactgctc tcccggatga ggatgatgac 1000

 ctgtgagaat gaagctggag cccagcgtca gaagtctagt tttataggca 1050

 gctgtcctgt gatgtcagcg gtgcagcgtg tgtgccacct cattattatc 1100

 tagctaagcg gaacatgtgc ttcatctgtg ggatgctgaa ggagatgagt 1150

 gggcttcgga gtgaatgtgg cagtttaaaa aataacttca ttgtttggac 1200

 ctgcatattt agctgttttg gaacgcagtt gattccttga gtttcatata 1250

 taagactgct gcagtcacat cacaatattc agtggtgaaa tcttgtttgt 1300

 tactgtcatt cccattcctt ttcgtttaga atcagaataa agttgtattt 1350

 caaatatcta agcaagtgaa ctcatccctt gtttataaat agcatttgga 1400

 aaccactaaa gtagggaagt tttatgccat gttaatattt gaattgcctt 1450

 gcttttatca cttaatttga aatctattgg gttaatttct ccctatgttt 1500

 atttttgtac atttgagcca tgtcacacaa actgatgatg acaggtcagc 1550

 agtattctat ttggttagaa gggttacatg gtgtaaatat tagtgcagtt 1600

 aagctaaagc agtgtttgct ccaccttcat attggctagg tagggtcacc 1650

 tagggaagca cttgctcaaa atctgtgacc tgtcagaata aaaatgtggt 1700

 ttgtacatat caaatagata ttttaagggt aatattttct tttatggcaa 1750

 aagtaatcat gttttaatgt agaacctcaa acaggatgga acatcagtgg 1800

 atggcaggag gttgggaatt cttgctgtta aaaataatta caaattttgc 1850

 acttttttgt ttgaatgtta gatgcttagt gtgaagttga tacgcaagga 1900

 aaatggtcca tgtttaccca cagttttcag gtactcctag actttaaaga 1950

 tgtcttgaac atttaagttc ttcagcagtt cacactacac cgtttttttg 2000

 tttttttttc ccccccggga gggttttttt gtagggcagc acagcagagc 2050

 aggacatgga tgaaatacta ggaatatgca cagtggggca gtgtgggggc 2100

 ttctcagtaa tggagaacag ttggtgaaac tttttttttt ttttaactaa 2150

 gcatttaatt tatcttgcat attttccaca tttaaaaatg aattaggtct 2200

 attaggataa ttaggagttt gatcccatca acactattct tgtagcagtt 2250

 aggaatcttg agctattttt ttctcatacg attactatag tccagtttac 2300

 caaagttttc tttagatgtc tgataatctt gagatgattg cttaccttaa 2350

 aaggtataga aaggatcact taaatatatg gaaaaatgaa ataagggtga 2400

 agctgaataa agttctactt actgtattaa ctggcaacag ttgagtttct 2450

 taagatctga attgctgtgt atgttacgct gtattcagaa ccagtttcta 2500

 accagcctgt gagatgggaa gttttttccc cataattggg atgaaacctt 2550

 tcattcaggt attttgaatt gaaggtgtat gtgttgtttg taaccttgtg 2600

 gagattgcaa gtggtgttga cattctggat cttctatgta acagttgaaa 2650

 tttggaagtg acgtcactta cctgtctaac gtggtgtggg agagaattta 2700

 caagtccttt attgaaagaa taattgttgc aaaatatatt gcttctactt 2750

 tgcctggaaa aaaatctatg tcgggtgcgg agaaagaggt aatgaaatgg 2800

 caggaattca tatcagctat catacc 2826

<210> 74
<211> 334
<212> PRT
<213> Homo sapien

<400> 74
 Gly Arg Leu Ser Arg Trp Val Val Arg Ala Arg Pro Gly Arg Gly
   1               5                  10                  15

 Arg Arg Arg Ala Trp Gly Arg Arg Ser Pro Arg Glu Pro Pro Phe
                  20                  25                  30

 His Pro Pro Leu Ser Ser Pro Ser Arg Ser Gln Ser Arg Ser His
                  35                  40                  45

 Pro Tyr Thr Ser Val Arg Arg Ser Pro Gly Pro Ala Ala Pro Asp
                  50                  55                  60

 Ala Glu Pro Ala Arg Arg Leu Pro Ala Pro Arg Pro Gly Arg His
                  65                  70                  75

 Gly Ala Ala Gly Gly Arg Pro Leu Trp Gly Gly His Val Gly Arg
                  80                  85                  90

 Trp Gly Arg Gly Ser Gly Ala Ala Met Gly Cys Gly Ala Ala Arg
                  95                 100                 105

 Ala Leu Ala Ser Val Leu Cys Leu Arg Arg Asn Ala Ala Met Ala
                 110                 115                 120

 Ala Gln Gly Glu Pro Gln Val Gln Phe Lys Leu Val Leu Val Gly
                 125                 130                 135

 Asp Gly Gly Thr Gly Lys Thr Thr Phe Val Lys Arg His Leu Thr
                 140                 145                 150

 Gly Glu Phe Glu Lys Lys Tyr Val Ala Thr Leu Gly Val Glu Val
                 155                 160                 165

 His Pro Leu Val Phe His Thr Asn Arg Gly Pro Ile Lys Phe Asn
                 170                 175                 180

 Val Trp Asp Thr Ala Gly Gln Glu Lys Phe Gly Gly Leu Arg Asp
                 185                 190                 195

 Gly Tyr Tyr Ile Gln Ala Gln Cys Ala Ile Ile Met Phe Asp Val
                 200                 205                 210

 Thr Ser Arg Val Thr Tyr Lys Asn Val Pro Asn Trp His Arg Asp
                 215                 220                 225

 Leu Val Arg Val Cys Glu Asn Ile Pro Ile Val Leu Cys Gly Asn
                 230                 235                 240

 Lys Val Asp Ile Lys Asp Arg Lys Val Lys Ala Lys Ser Ile Val
                 245                 250                 255

 Phe His Arg Lys Lys Asn Leu Gln Tyr Tyr Asp Ile Ser Ala Lys
                 260                 265                 270

 Ser Asn Tyr Asn Phe Glu Lys Pro Phe Leu Trp Leu Ala Arg Lys
                 275                 280                 285

 Leu Ile Gly Asp Pro Asn Leu Glu Phe Val Ala Met Pro Ala Leu
                 290                 295                 300

 Ala Pro Pro Glu Val Val Met Asp Pro Ala Leu Ala Ala Gln Tyr
                 305                 310                 315

 Glu His Asp Leu Glu Val Ala Gln Thr Thr Ala Leu Pro Asp Glu
                 320                 325                 330

 Asp Asp Asp Leu


<210> 75
<211> 1656
<212> DNA
<213> Mus musculus

<400> 75
 cgcccctgct ctcgcgccgg cgtcggctgc gtctccggcg tttgaattgc 50

 gcttccgcca tctttccagc ctcagtcgga cgggcgcgga ggcgcttctg 100

 gaaggaacgc cgcgatggct gcgcagggag agccccaggt ccagttcaaa 150

 cttgtattgg ttggtgatgg tggtactgga aaaacgacct tcgtgaaacg 200

 tcatttgact ggtgaatttg agaagaagta tgtagccacc ttgggtgttg 250

 aggttcatcc cctagtgttc cacaccaaca gaggacctat taagttcaat 300

 gtatgggaca cagccggcca ggagaaattc ggtggactga gagatggcta 350

 ttatatccaa gcccagtgtg ccatcataat gtttgatgta acatcgagag 400

 ttacttacaa gaatgtgcct aactggcata gagatctggt acgagtgtgt 450

 gaaaacatcc ccattgtgtt gtgtggcaac aaagtggata ttaaggacag 500

 gaaagtgaag gcgaaatcca ttgtcttcca ccgaaagaag aatcttcagt 550

 actacgacat ttctgccaaa agtaactaca actttgaaaa gcccttcctc 600

 tggcttgcta ggaagctcat tggagaccct aacttggaat ttgttgccat 650

 gcctgctctc gccccaccag aagttgtcat ggacccagct ttggcagcac 700

 agtatgagca cgacttagag gttgctcaga caactgctct cccggatgag 750

 gatgatgacc tgtgagaatg aagctggagc ccagcgtcag aagtctagtt 800

 ttataggcag ctgtcctgtg atgtcagcgg tgcagcgtgt gtgccacctc 850

 attattatct agctaagcgg aacatgtgct ttatctgtgg gatgctgaag 900

 gagatgagtg ggcttcggag tgaatgtggc agtttaaaaa ataacttcat 950

 tgtttggacc tgcatattta gctgtttgga cgcagttgat tccttgagtt 1000

 tcatatataa gactgctgca gtcacatcac aatattcagt ggtgaaatct 1050

 tgtttgttac tgtcattccc attccttttc tttagaatca gaataaagtt 1100

 gtatttcaaa tatctaagca agtgaactca tcccttgttt ataaatagca 1150

 tttggaaacc actaaagtag ggaagtttta tgccatgtta atatttgaat 1200

 tgccttgctt ttatcactta atttgaaatc tattgggtta atttctccct 1250

 atgtttattt ttgtacattt gagccatgtc acacaaactg atgatgacag 1300

 gtcagcagta ttctatttgg ttagaagggt tacatggtgt aaatattagt 1350

 gcagttaagc taaagcagtg tttgctccac cttcatattg gctaggtagg 1400

 gtcacctagg gaagcacttg ctcaaaatct gtgacctgtc agaataaaaa 1450

 tgtggtttgt acatatcaaa tagatatttt aagggtaata ttttctttta 1500

 tggcaaaagt aatcatgttt taatgtagaa cctcaaacag gatggaacat 1550

 cagtggatgg caggaggttg ggaattcttg ctgttaaaaa taattacaaa 1600

 ttttgcactt tttgtttgaa tgttagatgc ttagtgtgaa gttgatacgc 1650

 aagccg 1656

<210> 76
<211> 216
<212> PRT
<213> Mus musculus

<400> 76
 Met Ala Ala Gln Gly Glu Pro Gln Val Gln Phe Lys Leu Val Leu
   1               5                  10                  15

 Val Gly Asp Gly Gly Thr Gly Lys Thr Thr Phe Val Lys Arg His
                  20                  25                  30

 Leu Thr Gly Glu Phe Glu Lys Lys Tyr Val Ala Thr Leu Gly Val
                  35                  40                  45

 Glu Val His Pro Leu Val Phe His Thr Asn Arg Gly Pro Ile Lys
                  50                  55                  60

 Phe Asn Val Trp Asp Thr Ala Gly Gln Glu Lys Phe Gly Gly Leu
                  65                  70                  75

 Arg Asp Gly Tyr Tyr Ile Gln Ala Gln Cys Ala Ile Ile Met Phe
                  80                  85                  90

 Asp Val Thr Ser Arg Val Thr Tyr Lys Asn Val Pro Asn Trp His
                  95                 100                 105

 Arg Asp Leu Val Arg Val Cys Glu Asn Ile Pro Ile Val Leu Cys
                 110                 115                 120

 Gly Asn Lys Val Asp Ile Lys Asp Arg Lys Val Lys Ala Lys Ser
                 125                 130                 135

 Ile Val Phe His Arg Lys Lys Asn Leu Gln Tyr Tyr Asp Ile Ser
                 140                 145                 150

 Ala Lys Ser Asn Tyr Asn Phe Glu Lys Pro Phe Leu Trp Leu Ala
                 155                 160                 165

 Arg Lys Leu Ile Gly Asp Pro Asn Leu Glu Phe Val Ala Met Pro
                 170                 175                 180

 Ala Leu Ala Pro Pro Glu Val Val Met Asp Pro Ala Leu Ala Ala
                 185                 190                 195

 Gln Tyr Glu His Asp Leu Glu Val Ala Gln Thr Thr Ala Leu Pro
                 200                 205                 210

 Asp Glu Asp Asp Asp Leu
                 215

<210> 77
<211> 4459
<212> DNA
<213> Homo sapien

<400> 77
 gtttctctct ctccttctct ctctctctct ctctctcttt tttttccgcc 50

 ctagctgggg ctgtgttgga ggagaggaag aaagagagac agaggattgc 100

 attcatccgt tacgttcttg aaatttccta atagcaagac cagcgaagcg 150

 gttgcaccct tttcaatctt gcaaaggaaa aaaacaaaac aaaacaaaaa 200

 aaacccaagt ccccttcccg gcagtttttg ccttaaagct gccctcttga 250

 aattaatttt ttcccaggag agagatgtct tatcagggga agaaaaatat 300

 tccacgcatc acgagcgatc gtcttctgat caaaggaggt aaaattgtta 350

 atgatgacca gtcgttctat gcagacatat acatggaaga tgggttgatc 400

 aagcaaatag gagaaaatct gattgtgcca ggaggagtga agaccatcga 450

 ggcccactcc cggatggtga tccccggagg aattgacgtc cacactcgtt 500

 tccagatgcc tgatcaggga atgacgtctg ctgatgattt cttccaagga 550

 accaaggcgg ccctggctgg gggaaccact atgatcattg accacgttgt 600

 tcctgagcct gggacaagcc tgctcgctgc ctttgaccag tggagggaat 650

 gggccgacag caagtcctgc tgtgactact ctctgcatgt ggacatcagc 700

 gagtggcata agggcatcca ggaggagatg gaagcgcttg tgaaggatca 750

 cggggtaaat tccttcctcg tgtacatggc tttcaaagat cgcttccagc 800

 taacggattg ccagatttat gaagtactga gtgtgatccg ggatattggc 850

 gccatagccc aagtccacgc agaaaatggc gacatcattg cagaggagca 900

 gcagaggatc ctggatctgg gcatcacggg ccccgaggga catgtgctga 950

 gccgacctga ggaggtcgag gccgaagccg tgaatcgtgc catcaccatc 1000

 gccaaccaga ccaactgccc gctgtatatc accaaggtga tgagcaaaag 1050

 ctctgctgag gtcatcgccc aggcacggaa gaagggaact gtggtgtatg 1100

 gcgagcccat cactgccagc ttgggaacgg acggctccca ttactggagc 1150

 aagaactggg ccaaggctgc tgcctttgtc acctccccac ccttgagccc 1200

 tgatccaacc actccagact ttctcaactc cttgctgtcc tgtggagacc 1250

 tccaggtcac gggcagtgcc cattgcacgt ttaacactgc ccagaaggct 1300

 gtaggaaagg acaacttcac cctgattccg gagggcacca atggcactga 1350

 ggagcggatg tccgtcatct gggacaaggc tgtggtcact gggaagatgg 1400

 atgagaacca gtttgtggct gtgaccagca ccaatgcagc caaagtcttc 1450

 aacctttacc cccggaaagg ccgcattgct gtgggatccg atgccgacct 1500

 ggtcatctgg gaccccgaca gcgttaaaac catctctgcc aagacacaca 1550

 acagctctct cgagtacaac atctttgaag gcatggagtg ccgcggctcc 1600

 ccactggtgg tcatcagcca ggggaagatt gtcctggagg acggcaccct 1650

 gcatgtcacc gaaggctctg gacgctacat tccccggaag cccttccctg 1700

 attttgttta caagcgtatc aaggcaagga gcaggctggc tgagctgaga 1750

 ggggttcctc gtggcctgta tgacggacct gtgtgtgaag tgtctgtgac 1800

 gcccaagaca gtcactccag cctcctcggc caagacgtct cctgccaagc 1850

 agcaggcccc acctgtccgg aacctgcacc agtctggatt cagtttgtct 1900

 ggtgctcaga ttgatgacaa cattccccgc cgcaccaccc agcgtatcgt 1950

 ggcgcccccc ggtggccgtg ccaacatcac cagcctgggc tagagctcct 2000

 gggctgtgcg tccactgggg actggggatg ggacacctga ggacattctg 2050

 agacttcttt cttccttcct tttttttttt ttgttttttt ttttaagagc 2100

 ctgtgatagt tactgtggag cagccagttc atggggtccc ccttggggcc 2150

 ccacaccccg tctctcacca agagttactg attttgctca tccacttccc 2200

 tacacatcta tgggtatcac acccaagact acccaccaag ctcatacagg 2250

 gaaccacacc caacacttag acatgcgaac aagcagcccc cagcgagggt 2300

 ctccttcgcc ttcaacctcc tagtgtctgt tagcatcttc cttttcatgg 2350

 ggggagggaa gataaagtga attgcccaga gctgcctttt tcttttcttt 2400

 ttaaaaattt taagaagttt tccttgtggg gctggggagg ggccggggtc 2450

 agggagagtc tttttttttt tttttttaaa tactaaattg gaacatttaa 2500

 ttccatatta atacaagggg tttgaactgg acatcctaat gatgcaatta 2550

 cgtcatcacc cagctgattc cgggtggttg gcaaactcat cgtgtctgtc 2600

 ctgagaggct ccacaatgcc cacccgcatc gccattctgt agtcttcagg 2650

 gtcagctgtt gataaagggg caggcttgcg ttattggcct agattttgct 2700

 gcagattaaa tcctttgagg attctcttct cttttaccat ttttctgcgt 2750

 gctctcactc tctctttctc tctctagctt tttaattcat gaatattttc 2800

 gtgtctgtct ctctctctct ctgtgtttcc tccagccctt gtctcggaga 2850

 cggtgttttc ctcccttgcc ccattatctt ttcacctccc aggtctacca 2900

 tttcatggtg gtcgttgggt ccgcctaaag gatttgagcg tttgccattg 2950

 caagcatagt gctgtgtcat cctggtccat gtaggactgg tgctaaccac 3000

 ctgccatcat gaggatgtgt gctagagtgt gggaccctgg ccaagtgcag 3050

 gaatgggcca tgccgtctca cccacagtat cacacgtgga accgcagaca 3100

 gggcccagaa gctttagagg tatgaggctg cagaaccgga gagattttcc 3150

 tctgtgcagt gctctctggc taaagtcacg gtcaaaccta aacaccgagc 3200

 ctcattaacc caagtgaacc aaccaaagtc accagttcag aagtgctaag 3250

 ctaataggag tctgacccga gggcctgctg cttcctggtt aagtatcttt 3300

 tgagattcta gaacacatgg gagcttttta ttttcgggga aaaaccgtat 3350

 ttttttcttg tccaattatt tctaaagaca cactacatag aaagaggccc 3400

 tataaactca aaaagtcatt gggaaactta aagtctattc tactttgcaa 3450

 gaggagaaat gtgttttatg aacgatagat cacatcagaa ctcctgtggg 3500

 gaggaaacct tataaattaa acacatggcc cccttagaga ccacaggtga 3550

 tgtctgtctc catccttccc tctccttttc tgtcaccttt ccccctagct 3600

 ggctcctttg gacctacccc tgtccttgct gacttgtgtt gcattgtatt 3650

 ccaaacgtgt ttacaggttc tcttaagcaa tgttgtattt gcaggctttt 3700

 ctgaatacca aatctgcttt ttgtaaagcg taaaaacatc acaaagtagg 3750

 tcattccatc accacccttg tctctctaca cattttgcct ttggggatct 3800

 ggttggggtt ttgggttttt tgttgttgtt gtttatttgt tattttaaag 3850

 gtaaattgca cttttaaaaa aataattggt tgacttaata tatttgcttt 3900

 ttttctcacc tgcacttaga ggaaatttga acaagttgga aaaaaacaat 3950

 ttttgtttca attctaagaa acacttgcag ctctagtatt cacttgagtc 4000

 ttcctgtttt tcctgtaccg ggtcatggta atttttggtt gttttggttg 4050

 ttttcttaaa aaacaagtta aaacctgacg atttctgcag gctgtgtaag 4100

 catgtttacc tgttggcttg ctttgtgtgt ctgttaaatg aatgtcatat 4150

 gtaaatgcta aaataaatcg acagtgtctc agaactgaat aactgcagtg 4200

 acttgatgct ctaaaacagt gtaggattta agaatagatg gtttttaatc 4250

 ctggaaattg tgattgtgac ccatgagtgg aggaactttc agttctaaag 4300

 ctgataaagt gtgtagccag aagagtactt ttttttttgt aaccactgtc 4350

 ttgatggcaa aataattatg gtaaaaaaca agtctcgtgt ttattattcc 4400

 ttaagaactc tgtgttatat taccatggaa cgcctaataa agcaaaatgt 4450

 ggttgtttc 4459

<210> 78
<211> 572
<212> PRT
<213> Homo sapien

<400> 78
 Met Ser Tyr Gln Gly Lys Lys Asn Ile Pro Arg Ile Thr Ser Asp
   1               5                  10                  15

 Arg Leu Leu Ile Lys Gly Gly Lys Ile Val Asn Asp Asp Gln Ser
                  20                  25                  30

 Phe Tyr Ala Asp Ile Tyr Met Glu Asp Gly Leu Ile Lys Gln Ile
                  35                  40                  45

 Gly Glu Asn Leu Ile Val Pro Gly Gly Val Lys Thr Ile Glu Ala
                  50                  55                  60

 His Ser Arg Met Val Ile Pro Gly Gly Ile Asp Val His Thr Arg
                  65                  70                  75

 Phe Gln Met Pro Asp Gln Gly Met Thr Ser Ala Asp Asp Phe Phe
                  80                  85                  90

 Gln Gly Thr Lys Ala Ala Leu Ala Gly Gly Thr Thr Met Ile Ile
                  95                 100                 105

 Asp His Val Val Pro Glu Pro Gly Thr Ser Leu Leu Ala Ala Phe
                 110                 115                 120

 Asp Gln Trp Arg Glu Trp Ala Asp Ser Lys Ser Cys Cys Asp Tyr
                 125                 130                 135

 Ser Leu His Val Asp Ile Ser Glu Trp His Lys Gly Ile Gln Glu
                 140                 145                 150

 Glu Met Glu Ala Leu Val Lys Asp His Gly Val Asn Ser Phe Leu
                 155                 160                 165

 Val Tyr Met Ala Phe Lys Asp Arg Phe Gln Leu Thr Asp Cys Gln
                 170                 175                 180

 Ile Tyr Glu Val Leu Ser Val Ile Arg Asp Ile Gly Ala Ile Ala
                 185                 190                 195

 Gln Val His Ala Glu Asn Gly Asp Ile Ile Ala Glu Glu Gln Gln
                 200                 205                 210

 Arg Ile Leu Asp Leu Gly Ile Thr Gly Pro Glu Gly His Val Leu
                 215                 220                 225

 Ser Arg Pro Glu Glu Val Glu Ala Glu Ala Val Asn Arg Ala Ile
                 230                 235                 240

 Thr Ile Ala Asn Gln Thr Asn Cys Pro Leu Tyr Ile Thr Lys Val
                 245                 250                 255

 Met Ser Lys Ser Ser Ala Glu Val Ile Ala Gln Ala Arg Lys Lys
                 260                 265                 270

 Gly Thr Val Val Tyr Gly Glu Pro Ile Thr Ala Ser Leu Gly Thr
                 275                 280                 285

 Asp Gly Ser His Tyr Trp Ser Lys Asn Trp Ala Lys Ala Ala Ala
                 290                 295                 300

 Phe Val Thr Ser Pro Pro Leu Ser Pro Asp Pro Thr Thr Pro Asp
                 305                 310                 315

 Phe Leu Asn Ser Leu Leu Ser Cys Gly Asp Leu Gln Val Thr Gly
                 320                 325                 330

 Ser Ala His Cys Thr Phe Asn Thr Ala Gln Lys Ala Val Gly Lys
                 335                 340                 345

 Asp Asn Phe Thr Leu Ile Pro Glu Gly Thr Asn Gly Thr Glu Glu
                 350                 355                 360

 Arg Met Ser Val Ile Trp Asp Lys Ala Val Val Thr Gly Lys Met
                 365                 370                 375

 Asp Glu Asn Gln Phe Val Ala Val Thr Ser Thr Asn Ala Ala Lys
                 380                 385                 390

 Val Phe Asn Leu Tyr Pro Arg Lys Gly Arg Ile Ala Val Gly Ser
                 395                 400                 405

 Asp Ala Asp Leu Val Ile Trp Asp Pro Asp Ser Val Lys Thr Ile
                 410                 415                 420

 Ser Ala Lys Thr His Asn Ser Ser Leu Glu Tyr Asn Ile Phe Glu
                 425                 430                 435

 Gly Met Glu Cys Arg Gly Ser Pro Leu Val Val Ile Ser Gln Gly
                 440                 445                 450

 Lys Ile Val Leu Glu Asp Gly Thr Leu His Val Thr Glu Gly Ser
                 455                 460                 465

 Gly Arg Tyr Ile Pro Arg Lys Pro Phe Pro Asp Phe Val Tyr Lys
                 470                 475                 480

 Arg Ile Lys Ala Arg Ser Arg Leu Ala Glu Leu Arg Gly Val Pro
                 485                 490                 495

 Arg Gly Leu Tyr Asp Gly Pro Val Cys Glu Val Ser Val Thr Pro
                 500                 505                 510

 Lys Thr Val Thr Pro Ala Ser Ser Ala Lys Thr Ser Pro Ala Lys
                 515                 520                 525

 Gln Gln Ala Pro Pro Val Arg Asn Leu His Gln Ser Gly Phe Ser
                 530                 535                 540

 Leu Ser Gly Ala Gln Ile Asp Asp Asn Ile Pro Arg Arg Thr Thr
                 545                 550                 555

 Gln Arg Ile Val Ala Pro Pro Gly Gly Arg Ala Asn Ile Thr Ser
                 560                 565                 570

 Leu Gly


<210> 79
<211> 1630
<212> DNA
<213> Homo sapien

<400> 79
 agggccgggg tggggcgctg gcgtttccgt tgcttggatc agtctaggtg 50

 cagctgcgga tccttcagcg tctgcatctc ggcgtcgccc cgcgtaccgt 100

 cgcccggctc tccgccgctc tcccgggggt tcggggcact tgggtcccac 150

 agtctggtcc tgcttcacct tcccctgacc tgagtagtcg ccatggcaca 200

 ggttctcaga ggcactgtga ctgacttccc tggatttgat gagcgggctg 250

 atgcagaaac tcttcggaag gctatgaaag gcttgggcac agatgaggag 300

 agcatcctga ctctgttgac atcccgaagt aatgctcagc gccaggaaat 350

 ctctgcagct tttaagactc tgtttggcag ggatcttctg gatgacctga 400

 aatcagaact aactggaaaa tttgaaaaat taattgtggc tctgatgaaa 450

 ccctctcggc tttatgatgc ttatgaactg aaacatgcct tgaagggagc 500

 tggaacaaat gaaaaagtac tgacagaaat tattgcttca aggacacctg 550

 aagaactgag agccatcaaa caagtttatg aagaagaata tggctcaagc 600

 ctggaagatg acgtggtggg ggacacttca gggtactacc agcggatgtt 650

 ggtggttctc cttcaggcta acagagaccc tgatgctgga attgatgaag 700

 ctcaagttga acaagatgct caggctttat ttcaggctgg agaacttaaa 750

 tgggggacag atgaagaaaa gtttatcacc atctttggaa cacgaagtgt 800

 gtctcatttg agaaaggtgt ttgacaagta catgactata tcaggatttc 850

 aaattgagga aaccattgac cgcgagactt ctggcaattt agagcaacta 900

 ctccttgctg ttgtgaaatc tattcgaagt atacctgcct accttgcaga 950

 gaccctctat tatgctatga agggagctgg gacagatgat cataccctca 1000

 tcagagtcat ggtttccagg agtgagattg atctgtttaa catcaggaag 1050

 gagtttagga agaattttgc cacctctctt tattccatga ttaagggaga 1100

 tacatctggg gactataaga aagctcttct gctgctctgt ggagaagatg 1150

 actaacgtgt cacggggaag agctccctgc tgtgtgcctg caccacccca 1200

 ctgccttcct tcagcacctt tagctgcatt tgtatgccag tgcttaacac 1250

 attgccttat tcatactagc atgctcatga ccaacacata cacgtcatag 1300

 aagaaaatag tggtgcttct ttctgatctc tagtggagat ctctttgact 1350

 gctgtagtac taaagtgtac ttaatgttac taagtttaat gcctggccat 1400

 tttccattta tatatatttt ttaagaggct agagtgcttt tagccttttt 1450

 taaaaactcc atttatatta catttgtaac catgatactt taattagaag 1500

 cttagccttg aaattgtgaa ctcttggaaa tgttattagt gaagttcgca 1550

 actaaactaa acctgtaaaa ttatgatgat tgtattcaaa agattaatga 1600

 aaaataaaca tttctgtccc cctgaattat 1630

<210> 80
<211> 320
<212> PRT
<213> Homo sapien

<400> 80
 Met Ala Gln Val Leu Arg Gly Thr Val Thr Asp Phe Pro Gly Phe
   1               5                  10                  15

 Asp Glu Arg Ala Asp Ala Glu Thr Leu Arg Lys Ala Met Lys Gly
                  20                  25                  30

 Leu Gly Thr Asp Glu Glu Ser Ile Leu Thr Leu Leu Thr Ser Arg
                  35                  40                  45

 Ser Asn Ala Gln Arg Gln Glu Ile Ser Ala Ala Phe Lys Thr Leu
                  50                  55                  60

 Phe Gly Arg Asp Leu Leu Asp Asp Leu Lys Ser Glu Leu Thr Gly
                  65                  70                  75

 Lys Phe Glu Lys Leu Ile Val Ala Leu Met Lys Pro Ser Arg Leu
                  80                  85                  90

 Tyr Asp Ala Tyr Glu Leu Lys His Ala Leu Lys Gly Ala Gly Thr
                  95                 100                 105

 Asn Glu Lys Val Leu Thr Glu Ile Ile Ala Ser Arg Thr Pro Glu
                 110                 115                 120

 Glu Leu Arg Ala Ile Lys Gln Val Tyr Glu Glu Glu Tyr Gly Ser
                 125                 130                 135

 Ser Leu Glu Asp Asp Val Val Gly Asp Thr Ser Gly Tyr Tyr Gln
                 140                 145                 150

 Arg Met Leu Val Val Leu Leu Gln Ala Asn Arg Asp Pro Asp Ala
                 155                 160                 165

 Gly Ile Asp Glu Ala Gln Val Glu Gln Asp Ala Gln Ala Leu Phe
                 170                 175                 180

 Gln Ala Gly Glu Leu Lys Trp Gly Thr Asp Glu Glu Lys Phe Ile
                 185                 190                 195

 Thr Ile Phe Gly Thr Arg Ser Val Ser His Leu Arg Lys Val Phe
                 200                 205                 210

 Asp Lys Tyr Met Thr Ile Ser Gly Phe Gln Ile Glu Glu Thr Ile
                 215                 220                 225

 Asp Arg Glu Thr Ser Gly Asn Leu Glu Gln Leu Leu Leu Ala Val
                 230                 235                 240

 Val Lys Ser Ile Arg Ser Ile Pro Ala Tyr Leu Ala Glu Thr Leu
                 245                 250                 255

 Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp His Thr Leu Ile
                 260                 265                 270

 Arg Val Met Val Ser Arg Ser Glu Ile Asp Leu Phe Asn Ile Arg
                 275                 280                 285

 Lys Glu Phe Arg Lys Asn Phe Ala Thr Ser Leu Tyr Ser Met Ile
                 290                 295                 300

 Lys Gly Asp Thr Ser Gly Asp Tyr Lys Lys Ala Leu Leu Leu Leu
                 305                 310                 315

 Cys Gly Glu Asp Asp
                 320

<210> 81
<211> 1436
<212> DNA
<213> Homo sapien

<400> 81
 agtgtggtca ggcggctcgg actgagcagg actttcctta tcccagttga 50

 ttgtgcagaa tacactgcct atcgcttgtc ttctattcac catggcttct 100

 tctgatatcc aggtgaaaga actggagaag cgtgcctcag gccaggcttt 150

 tgagctgatt ctcagccctc ggtcaaaaga atctgttcca gaattccccc 200

 tttcccctcc aaagaagaag gatctttccc tggaggaaat tcagaagaaa 250

 ttagaagctg cagaagaaag acgcaagtcc catgaagctg aggtcttgaa 300

 gcagctggct gagaaacgag agcacgagaa agaagtgctt cagaaggcaa 350

 tagaagagaa caacaacttc agtaaaatgg cagaagagaa actgacccac 400

 aaaatggaag ctaataaaga gaaccgagag gcacaaatgg ctgccaaact 450

 ggaacgtttg cgagagaagg ataagcacat tgaagaagtg cggaagaaca 500

 aagaatccaa agaccctgct gacgagactg aagctgacta atttgttctg 550

 agaactgact ttctccccat ccccttccta aatatccaaa gactgtactg 600

 gccagtgtca ttttattttt tccctcctga caaatatttt agaagctaat 650

 gtaggactgt ataggtagat ccagatccag actgtaagat gttgttttag 700

 gggctaaagg ggagaaactg aaagtgtttt actctttttc taaagtgttg 750

 gtctttctaa tgtagctatt tttcttgttg catcttttct acttcagtac 800

 acttggtgta ctgggttaat ggctagtact gtattggctc tgtgaaaaca 850

 tatttgtgaa aagagtatgt agtggcttct tttgaactgt tagatgctga 900

 atatctgttc acttttcaat cccaattctg tcccaatctt accagatgct 950

 actggacttg aatggttaat aaaactgcac agtgctgttg gtggcagtga 1000

 cttcttttga gttaggttaa taaatcaagc catagagccc ctcctggttg 1050

 atacttgttc cagatggggc ctttggggct ggtagaaata cccaacgcac 1100

 aaatgaccgc acgttctctg ccccgtttct tgccccagtg tggtttgcat 1150

 tgtctccttc cacaatgact gctttgtttg gatgcctcag cccaggtcag 1200

 ctgttacttt ctttcagatg tttatttgca aacaaccatt ttttgttctg 1250

 tgtccctttt aaaaggcaga ttaaaagcac aagcgtgttt ctagagaaca 1300

 gttgagagag aatctcaaga ttctacttgg tggtttgctt gctctacgtt 1350

 acaggtgggg catgtcctca tcctttcctg ccataaaagc tatgacacga 1400

 gaatcagaat attaataaaa ctttatgtac tgctgt 1436

<210> 82
<211> 149
<212> PRT
<213> Homo sapien

<400> 82
 Met Ala Ser Ser Asp Ile Gln Val Lys Glu Leu Glu Lys Arg Ala
   1               5                  10                  15

 Ser Gly Gln Ala Phe Glu Leu Ile Leu Ser Pro Arg Ser Lys Glu
                  20                  25                  30

 Ser Val Pro Glu Phe Pro Leu Ser Pro Pro Lys Lys Lys Asp Leu
                  35                  40                  45

 Ser Leu Glu Glu Ile Gln Lys Lys Leu Glu Ala Ala Glu Glu Arg
                  50                  55                  60

 Arg Lys Ser His Glu Ala Glu Val Leu Lys Gln Leu Ala Glu Lys
                  65                  70                  75

 Arg Glu His Glu Lys Glu Val Leu Gln Lys Ala Ile Glu Glu Asn
                  80                  85                  90

 Asn Asn Phe Ser Lys Met Ala Glu Glu Lys Leu Thr His Lys Met
                  95                 100                 105

 Glu Ala Asn Lys Glu Asn Arg Glu Ala Gln Met Ala Ala Lys Leu
                 110                 115                 120

 Glu Arg Leu Arg Glu Lys Asp Lys His Ile Glu Glu Val Arg Lys
                 125                 130                 135

 Asn Lys Glu Ser Lys Asp Pro Ala Asp Glu Thr Glu Ala Asp
                 140                 145

<210> 83
<211> 2062
<212> DNA
<213> Homo sapien

<400> 83
 gtcagtccct cctgtagccg ccgccgccgc cgcccgccgc ccctctgcca 50

 gcagctccgg cgccacctcg ggccggcgtc tccggcgggc gggagccagg 100

 cgctgacggg cgcggcgggg gcggccgagc gctcctgcgg ctgcgactca 150

 ggctccggcg tctgcgcttc cccatggggc tggcctgcgg cgcctgggcg 200

 ctctgagatt gtcactgctg ttccaagggc acacgcagag ggatttggaa 250

 ttcctggaga gttgcctttg tgagaagctg gaaatatttc tttcaattcc 300

 atctcttagt tttccatagg aacatcaaga aatcatgaac aactttggta 350

 atgaagagtt tgactgccac ttcctcgatg aaggttttac tgccaaggac 400

 attctggacc agaaaattaa tgaagtttct tcttctgatg ataaggatgc 450

 cttctatgtg gcagacctgg gagacattct aaagaaacat ctgaggtggt 500

 taaaagctct ccctcgtgtc accccctttt atgcagtcaa atgtaatgat 550

 agcaaagcca tcgtgaagac ccttgctgct accgggacag gatttgactg 600

 tgctagcaag actgaaatac agttggtgca gagtctgggg gtgcctccag 650

 agaggattat ctatgcaaat ccttgtaaac aagtatctca aattaagtat 700

 gctgctaata atggagtcca gatgatgact tttgatagtg aagttgagtt 750

 gatgaaagtt gccagagcac atcccaaagc aaagttggtt ttgcggattg 800

 ccactgatga ttccaaagca gtctgtcgtc tcagtgtgaa attcggtgcc 850

 acgctcagaa ccagcaggct ccttttggaa cgggcgaaag agctaaatat 900

 cgatgttgtt ggtgtcagct tccatgtagg aagcggctgt accgatcctg 950

 agaccttcgt gcaggcaatc tctgatgccc gctgtgtttt tgacatgggg 1000

 gctgaggttg gtttcagcat gtatctgctt gatattggcg gtggctttcc 1050

 tggatctgag gatgtgaaac ttaaatttga agagatcacc ggcgtaatca 1100

 acccagcgtt ggacaaatac tttccgtcag actctggagt gagaatcata 1150

 gctgagcccg gcagatacta tgttgcatca gctttcacgc ttgcagttaa 1200

 tatcattgcc aagaaaattg tattaaagga acagacgggc tctgatgacg 1250

 aagatgagtc gagtgagcag acctttatgt attatgtgaa tgatggcgtc 1300

 tatggatcat ttaattgcat actctatgac cacgcacatg taaagcccct 1350

 tctgcaaaag agacctaaac cagatgagaa gtattattca tccagcatat 1400

 ggggaccaac atgtgatggc ctcgatcgga ttgttgagcg ctgtgacctg 1450

 cctgaaatgc atgtgggtga ttggatgctc tttgaaaaca tgggcgctta 1500

 cactgttgct gctgcctcta cgttcaatgg cttccagagg ccgacgatct 1550

 actatgtgat gtcagggcct gcgtggcaac tcatgcagca attccagaac 1600

 cccgacttcc cacccgaagt agaggaacag gatgccagca ccctgcctgt 1650

 gtcttgtgcc tgggagagtg ggatgaaacg ccacagagca gcctgtgctt 1700

 cggctagtat taatgtgtag atagcactct ggtagctgtt aactgcaagt 1750

 ttagcttgaa ttaagggatt tggggggacc atgtaactta attactgcta 1800

 gttttgaaat gtctttgtaa gagtagggtc gccatgatgc agccatatgg 1850

 aagactagga tatgggtcac acttatctgt gttcctatgg aaactatttg 1900

 aatatttgtt ttatatggat ttttattcac tcttcagaca cgctactcaa 1950

 gagtgcccct cagctgctga acaagcattt gtagcttgta caatggcaga 2000

 atgggccaaa agcttagtgt tgtgacctgt ttttaaaata aagtatcttg 2050

 aaataattag gc 2062

<210> 84
<211> 461
<212> PRT
<213> Homo sapien

<400> 84
 Met Asn Asn Phe Gly Asn Glu Glu Phe Asp Cys His Phe Leu Asp
   1               5                  10                  15

 Glu Gly Phe Thr Ala Lys Asp Ile Leu Asp Gln Lys Ile Asn Glu
                  20                  25                  30

 Val Ser Ser Ser Asp Asp Lys Asp Ala Phe Tyr Val Ala Asp Leu
                  35                  40                  45

 Gly Asp Ile Leu Lys Lys His Leu Arg Trp Leu Lys Ala Leu Pro
                  50                  55                  60

 Arg Val Thr Pro Phe Tyr Ala Val Lys Cys Asn Asp Ser Lys Ala
                  65                  70                  75

 Ile Val Lys Thr Leu Ala Ala Thr Gly Thr Gly Phe Asp Cys Ala
                  80                  85                  90

 Ser Lys Thr Glu Ile Gln Leu Val Gln Ser Leu Gly Val Pro Pro
                  95                 100                 105

 Glu Arg Ile Ile Tyr Ala Asn Pro Cys Lys Gln Val Ser Gln Ile
                 110                 115                 120

 Lys Tyr Ala Ala Asn Asn Gly Val Gln Met Met Thr Phe Asp Ser
                 125                 130                 135

 Glu Val Glu Leu Met Lys Val Ala Arg Ala His Pro Lys Ala Lys
                 140                 145                 150

 Leu Val Leu Arg Ile Ala Thr Asp Asp Ser Lys Ala Val Cys Arg
                 155                 160                 165

 Leu Ser Val Lys Phe Gly Ala Thr Leu Arg Thr Ser Arg Leu Leu
                 170                 175                 180

 Leu Glu Arg Ala Lys Glu Leu Asn Ile Asp Val Val Gly Val Ser
                 185                 190                 195

 Phe His Val Gly Ser Gly Cys Thr Asp Pro Glu Thr Phe Val Gln
                 200                 205                 210

 Ala Ile Ser Asp Ala Arg Cys Val Phe Asp Met Gly Ala Glu Val
                 215                 220                 225

 Gly Phe Ser Met Tyr Leu Leu Asp Ile Gly Gly Gly Phe Pro Gly
                 230                 235                 240

 Ser Glu Asp Val Lys Leu Lys Phe Glu Glu Ile Thr Gly Val Ile
                 245                 250                 255

 Asn Pro Ala Leu Asp Lys Tyr Phe Pro Ser Asp Ser Gly Val Arg
                 260                 265                 270

 Ile Ile Ala Glu Pro Gly Arg Tyr Tyr Val Ala Ser Ala Phe Thr
                 275                 280                 285

 Leu Ala Val Asn Ile Ile Ala Lys Lys Ile Val Leu Lys Glu Gln
                 290                 295                 300

 Thr Gly Ser Asp Asp Glu Asp Glu Ser Ser Glu Gln Thr Phe Met
                 305                 310                 315

 Tyr Tyr Val Asn Asp Gly Val Tyr Gly Ser Phe Asn Cys Ile Leu
                 320                 325                 330

 Tyr Asp His Ala His Val Lys Pro Leu Leu Gln Lys Arg Pro Lys
                 335                 340                 345

 Pro Asp Glu Lys Tyr Tyr Ser Ser Ser Ile Trp Gly Pro Thr Cys
                 350                 355                 360

 Asp Gly Leu Asp Arg Ile Val Glu Arg Cys Asp Leu Pro Glu Met
                 365                 370                 375

 His Val Gly Asp Trp Met Leu Phe Glu Asn Met Gly Ala Tyr Thr
                 380                 385                 390

 Val Ala Ala Ala Ser Thr Phe Asn Gly Phe Gln Arg Pro Thr Ile
                 395                 400                 405

 Tyr Tyr Val Met Ser Gly Pro Ala Trp Gln Leu Met Gln Gln Phe
                 410                 415                 420

 Gln Asn Pro Asp Phe Pro Pro Glu Val Glu Glu Gln Asp Ala Ser
                 425                 430                 435

 Thr Leu Pro Val Ser Cys Ala Trp Glu Ser Gly Met Lys Arg His
                 440                 445                 450

 Arg Ala Ala Cys Ala Ser Ala Ser Ile Asn Val
                 455                 460

<210> 85
<211> 2202
<212> DNA
<213> Homo sapien

<400> 85
 cacgcttgcc gccgccccgc agaaatgctt cggttaccca cagtctttcg 50

 ccagatgaga ccggtgtcca gggtactggc tcctcatctc actcgggctt 100

 atgccaaaga tgtaaaattt ggtgcagatg cccgagcctt aatgcttcaa 150

 ggtgtagacc ttttagccga tgctgtggcc gttacaatgg ggccaaaggg 200

 aagaacagtg attattgagc agggttgggg aagtcccaaa gtaacaaaag 250

 atggtgtgac tgttgcaaag tcaattgact taaaagataa atacaagaac 300

 attggagcta aacttgttca agatgttgcc aataacacaa atgaagaagc 350

 tggggatggc actaccactg ctactgtact ggcacgctct atagccaagg 400

 aaggcttcga gaagattagc aaaggtgcta atccagtgga aatcaggaga 450

 ggtgtgatgt tagctgttga tgctgtaatt gctgaactta aaaagcagtc 500

 taaacctgtg accacccctg aagaaattgc acaggttgct acgatttctg 550

 caaacggaga caaagaaatt ggcaatatca tctctgatgc aatgaaaaaa 600

 gttggaagaa agggtgtcat cacagtaaag gatggaaaaa cactgaatga 650

 tgaattagaa attattgaag gcatgaagtt tgatcgaggc tatatttctc 700

 catactttat taatacatca aaaggtcaga aatgtgaatt ccaggatgcc 750

 tatgttctgt tgagtgaaaa gaaaatttct agtatccagt ccattgtacc 800

 tgctcttgaa attgccaatg ctcaccgtaa gcctttggtc ataatcgctg 850

 aagatgttga tggagaagct ctaagtacac tcgtcttgaa taggctaaag 900

 gttggtcttc aggttgtggc agtcaaggct ccagggtttg gtgacaatag 950

 aaagaaccag cttaaagata tggctattgc tactggtggt gcagtgtttg 1000

 gagaagaggg attgaccctg aatcttgaag acgttcagcc tcatgactta 1050

 ggaaaagttg gagaggtcat tgtgaccaaa gacgatgcca tgctcttaaa 1100

 aggaaaaggt gacaaggctc aaattgaaaa acgtattcaa gaaatcattg 1150

 agcagttaga tgtcacaact agtgaatatg aaaaggaaaa actgaatgaa 1200

 cggcttgcaa aactttcaga tggagtggct gtgctgaagg ttggtgggac 1250

 aagtgatgtt gaagtgaatg aaaagaaaga cagagttaca gatgccctta 1300

 atgctacaag agctgctgtt gaagaaggca ttgttttggg agggggttgt 1350

 gccctccttc gatgcattcc agccttggac tcattgactc cagctaatga 1400

 agatcaaaaa attggtatag aaattattaa aagaacactc aaaattccag 1450

 caatgaccat tgctaagaat gcaggtgttg aaggatcttt gatagttgag 1500

 aaaattatgc aaagttcctc agaagttggt tatgatgcta tggctggaga 1550

 ttttgtgaat atggtggaaa aaggaatcat tgacccaaca aaggttgtga 1600

 gaactgcttt attggatgct gctggtgtgg cctctctgtt aactacagca 1650

 gaagttgtag tcacagaaat tcctaaagaa gagaaggacc ctggaatggg 1700

 tgcaatgggt ggaatgggag gtggtatggg aggtggcatg ttctaactcc 1750

 tagactagtg ctttaccttt attaatgaac tgtgacagga agcccaaggc 1800

 agtgttcctc accaataact tcagagaagt cagttggaga aaatgaagaa 1850

 aaaggctggc tgaaaatcac tataaccatc agttactggt ttcagttgac 1900

 aaaatatata atggtttact gctgtcattg tccatgccta cagataattt 1950

 attttgtatt tttgaataaa aaacatttgt acattcctga tactgggtac 2000

 aagagccatg taccagtgta ctgctttcaa cttaaatcac tgaggcattt 2050

 ttactactat tctgttaaaa tcaggatttt agtgcttgcc accaccagat 2100

 gagaagttaa gcagcctttc tgtggagagt gagaataatt gtgtacaaag 2150

 tagagaagta tccaattatg tgacaacctt tgtgtaataa aaatttgttt 2200

 aa 2202

<210> 86
<211> 573
<212> PRT
<213> Homo sapien

<400> 86
 Met Leu Arg Leu Pro Thr Val Phe Arg Gln Met Arg Pro Val Ser
   1               5                  10                  15

 Arg Val Leu Ala Pro His Leu Thr Arg Ala Tyr Ala Lys Asp Val
                  20                  25                  30

 Lys Phe Gly Ala Asp Ala Arg Ala Leu Met Leu Gln Gly Val Asp
                  35                  40                  45

 Leu Leu Ala Asp Ala Val Ala Val Thr Met Gly Pro Lys Gly Arg
                  50                  55                  60

 Thr Val Ile Ile Glu Gln Gly Trp Gly Ser Pro Lys Val Thr Lys
                  65                  70                  75

 Asp Gly Val Thr Val Ala Lys Ser Ile Asp Leu Lys Asp Lys Tyr
                  80                  85                  90

 Lys Asn Ile Gly Ala Lys Leu Val Gln Asp Val Ala Asn Asn Thr
                  95                 100                 105

 Asn Glu Glu Ala Gly Asp Gly Thr Thr Thr Ala Thr Val Leu Ala
                 110                 115                 120

 Arg Ser Ile Ala Lys Glu Gly Phe Glu Lys Ile Ser Lys Gly Ala
                 125                 130                 135

 Asn Pro Val Glu Ile Arg Arg Gly Val Met Leu Ala Val Asp Ala
                 140                 145                 150

 Val Ile Ala Glu Leu Lys Lys Gln Ser Lys Pro Val Thr Thr Pro
                 155                 160                 165

 Glu Glu Ile Ala Gln Val Ala Thr Ile Ser Ala Asn Gly Asp Lys
                 170                 175                 180

 Glu Ile Gly Asn Ile Ile Ser Asp Ala Met Lys Lys Val Gly Arg
                 185                 190                 195

 Lys Gly Val Ile Thr Val Lys Asp Gly Lys Thr Leu Asn Asp Glu
                 200                 205                 210

 Leu Glu Ile Ile Glu Gly Met Lys Phe Asp Arg Gly Tyr Ile Ser
                 215                 220                 225

 Pro Tyr Phe Ile Asn Thr Ser Lys Gly Gln Lys Cys Glu Phe Gln
                 230                 235                 240

 Asp Ala Tyr Val Leu Leu Ser Glu Lys Lys Ile Ser Ser Ile Gln
                 245                 250                 255

 Ser Ile Val Pro Ala Leu Glu Ile Ala Asn Ala His Arg Lys Pro
                 260                 265                 270

 Leu Val Ile Ile Ala Glu Asp Val Asp Gly Glu Ala Leu Ser Thr
                 275                 280                 285

 Leu Val Leu Asn Arg Leu Lys Val Gly Leu Gln Val Val Ala Val
                 290                 295                 300

 Lys Ala Pro Gly Phe Gly Asp Asn Arg Lys Asn Gln Leu Lys Asp
                 305                 310                 315

 Met Ala Ile Ala Thr Gly Gly Ala Val Phe Gly Glu Glu Gly Leu
                 320                 325                 330

 Thr Leu Asn Leu Glu Asp Val Gln Pro His Asp Leu Gly Lys Val
                 335                 340                 345

 Gly Glu Val Ile Val Thr Lys Asp Asp Ala Met Leu Leu Lys Gly
                 350                 355                 360

 Lys Gly Asp Lys Ala Gln Ile Glu Lys Arg Ile Gln Glu Ile Ile
                 365                 370                 375

 Glu Gln Leu Asp Val Thr Thr Ser Glu Tyr Glu Lys Glu Lys Leu
                 380                 385                 390

 Asn Glu Arg Leu Ala Lys Leu Ser Asp Gly Val Ala Val Leu Lys
                 395                 400                 405

 Val Gly Gly Thr Ser Asp Val Glu Val Asn Glu Lys Lys Asp Arg
                 410                 415                 420

 Val Thr Asp Ala Leu Asn Ala Thr Arg Ala Ala Val Glu Glu Gly
                 425                 430                 435

 Ile Val Leu Gly Gly Gly Cys Ala Leu Leu Arg Cys Ile Pro Ala
                 440                 445                 450

 Leu Asp Ser Leu Thr Pro Ala Asn Glu Asp Gln Lys Ile Gly Ile
                 455                 460                 465

 Glu Ile Ile Lys Arg Thr Leu Lys Ile Pro Ala Met Thr Ile Ala
                 470                 475                 480

 Lys Asn Ala Gly Val Glu Gly Ser Leu Ile Val Glu Lys Ile Met
                 485                 490                 495

 Gln Ser Ser Ser Glu Val Gly Tyr Asp Ala Met Ala Gly Asp Phe
                 500                 505                 510

 Val Asn Met Val Glu Lys Gly Ile Ile Asp Pro Thr Lys Val Val
                 515                 520                 525

 Arg Thr Ala Leu Leu Asp Ala Ala Gly Val Ala Ser Leu Leu Thr
                 530                 535                 540

 Thr Ala Glu Val Val Val Thr Glu Ile Pro Lys Glu Glu Lys Asp
                 545                 550                 555

 Pro Gly Met Gly Ala Met Gly Gly Met Gly Gly Gly Met Gly Gly
                 560                 565                 570

 Gly Met Phe


<210> 87
<211> 2202
<212> DNA
<213> Homo sapien

<400> 87
 cacgcttgcc gccgccccgc agaaatgctt cggttaccca cagtctttcg 50

 ccagatgaga ccggtgtcca gggtactggc tcctcatctc actcgggctt 100

 atgccaaaga tgtaaaattt ggtgcagatg cccgagcctt aatgcttcaa 150

 ggtgtagacc ttttagccga tgctgtggcc gttacaatgg ggccaaaggg 200

 aagaacagtg attattgagc agggttgggg aagtcccaaa gtaacaaaag 250

 atggtgtgac tgttgcaaag tcaattgact taaaagataa atacaagaac 300

 attggagcta aacttgttca agatgttgcc aataacacaa atgaagaagc 350

 tggggatggc actaccactg ctactgtact ggcacgctct atagccaagg 400

 aaggcttcga gaagattagc aaaggtgcta atccagtgga aatcaggaga 450

 ggtgtgatgt tagctgttga tgctgtaatt gctgaactta aaaagcagtc 500

 taaacctgtg accacccctg aagaaattgc acaggttgct acgatttctg 550

 caaacggaga caaagaaatt ggcaatatca tctctgatgc aatgaaaaaa 600

 gttggaagaa agggtgtcat cacagtaaag gatggaaaaa cactgaatga 650

 tgaattagaa attattgaag gcatgaagtt tgatcgaggc tatatttctc 700

 catactttat taatacatca aaaggtcaga aatgtgaatt ccaggatgcc 750

 tatgttctgt tgagtgaaaa gaaaatttct agtatccagt ccattgtacc 800

 tgctcttgaa attgccaatg ctcaccgtaa gcctttggtc ataatcgctg 850

 aagatgttga tggagaagct ctaagtacac tcgtcttgaa taggctaaag 900

 gttggtcttc aggttgtggc agtcaaggct ccagggtttg gtgacaatag 950

 aaagaaccag cttaaagata tggctattgc tactggtggt gcagtgtttg 1000

 gagaagaggg attgaccctg aatcttgaag acgttcagcc tcatgactta 1050

 ggaaaagttg gagaggtcat tgtgaccaaa gacgatgcca tgctcttaaa 1100

 aggaaaaggt gacaaggctc aaattgaaaa acgtattcaa gaaatcattg 1150

 agcagttaga tgtcacaact agtgaatatg aaaaggaaaa actgaatgaa 1200

 cggcttgcaa aactttcaga tggagtggct gtgctgaagg ttggtgggac 1250

 aagtgatgtt gaagtgaatg aaaagaaaga cagagttaca gatgccctta 1300

 atgctacaag agctgctgtt gaagaaggca ttgttttggg agggggttgt 1350

 gccctccttc gatgcattcc agccttggac tcattgactc cagctaatga 1400

 agatcaaaaa attggtatag aaattattaa aagaacactc aaaattccag 1450

 caatgaccat tgctaagaat gcaggtgttg aaggatcttt gatagttgag 1500

 aaaattatgc aaagttcctc agaagttggt tatgatgcta tggctggaga 1550

 ttttgtgaat atggtggaaa aaggaatcat tgacccaaca aaggttgtga 1600

 gaactgcttt attggatgct gctggtgtgg cctctctgtt aactacagca 1650

 gaagttgtag tcacagaaat tcctaaagaa gagaaggacc ctggaatggg 1700

 tgcaatgggt ggaatgggag gtggtatggg aggtggcatg ttctaactcc 1750

 tagactagtg ctttaccttt attaatgaac tgtgacagga agcccaaggc 1800

 agtgttcctc accaataact tcagagaagt cagttggaga aaatgaagaa 1850

 aaaggctggc tgaaaatcac tataaccatc agttactggt ttcagttgac 1900

 aaaatatata atggtttact gctgtcattg tccatgccta cagataattt 1950

 attttgtatt tttgaataaa aaacatttgt acattcctga tactgggtac 2000

 aagagccatg taccagtgta ctgctttcaa cttaaatcac tgaggcattt 2050

 ttactactat tctgttaaaa tcaggatttt agtgcttgcc accaccagat 2100

 gagaagttaa gcagcctttc tgtggagagt gagaataatt gtgtacaaag 2150

 tagagaagta tccaattatg tgacaacctt tgtgtaataa aaatttgttt 2200

 aa 2202

<210> 88
<211> 573
<212> PRT
<213> Homo sapien

<400> 88
 Met Leu Arg Leu Pro Thr Val Phe Arg Gln Met Arg Pro Val Ser
   1               5                  10                  15

 Arg Val Leu Ala Pro His Leu Thr Arg Ala Tyr Ala Lys Asp Val
                  20                  25                  30

 Lys Phe Gly Ala Asp Ala Arg Ala Leu Met Leu Gln Gly Val Asp
                  35                  40                  45

 Leu Leu Ala Asp Ala Val Ala Val Thr Met Gly Pro Lys Gly Arg
                  50                  55                  60

 Thr Val Ile Ile Glu Gln Gly Trp Gly Ser Pro Lys Val Thr Lys
                  65                  70                  75

 Asp Gly Val Thr Val Ala Lys Ser Ile Asp Leu Lys Asp Lys Tyr
                  80                  85                  90

 Lys Asn Ile Gly Ala Lys Leu Val Gln Asp Val Ala Asn Asn Thr
                  95                 100                 105

 Asn Glu Glu Ala Gly Asp Gly Thr Thr Thr Ala Thr Val Leu Ala
                 110                 115                 120

 Arg Ser Ile Ala Lys Glu Gly Phe Glu Lys Ile Ser Lys Gly Ala
                 125                 130                 135

 Asn Pro Val Glu Ile Arg Arg Gly Val Met Leu Ala Val Asp Ala
                 140                 145                 150

 Val Ile Ala Glu Leu Lys Lys Gln Ser Lys Pro Val Thr Thr Pro
                 155                 160                 165

 Glu Glu Ile Ala Gln Val Ala Thr Ile Ser Ala Asn Gly Asp Lys
                 170                 175                 180

 Glu Ile Gly Asn Ile Ile Ser Asp Ala Met Lys Lys Val Gly Arg
                 185                 190                 195

 Lys Gly Val Ile Thr Val Lys Asp Gly Lys Thr Leu Asn Asp Glu
                 200                 205                 210

 Leu Glu Ile Ile Glu Gly Met Lys Phe Asp Arg Gly Tyr Ile Ser
                 215                 220                 225

 Pro Tyr Phe Ile Asn Thr Ser Lys Gly Gln Lys Cys Glu Phe Gln
                 230                 235                 240

 Asp Ala Tyr Val Leu Leu Ser Glu Lys Lys Ile Ser Ser Ile Gln
                 245                 250                 255

 Ser Ile Val Pro Ala Leu Glu Ile Ala Asn Ala His Arg Lys Pro
                 260                 265                 270

 Leu Val Ile Ile Ala Glu Asp Val Asp Gly Glu Ala Leu Ser Thr
                 275                 280                 285

 Leu Val Leu Asn Arg Leu Lys Val Gly Leu Gln Val Val Ala Val
                 290                 295                 300

 Lys Ala Pro Gly Phe Gly Asp Asn Arg Lys Asn Gln Leu Lys Asp
                 305                 310                 315

 Met Ala Ile Ala Thr Gly Gly Ala Val Phe Gly Glu Glu Gly Leu
                 320                 325                 330

 Thr Leu Asn Leu Glu Asp Val Gln Pro His Asp Leu Gly Lys Val
                 335                 340                 345

 Gly Glu Val Ile Val Thr Lys Asp Asp Ala Met Leu Leu Lys Gly
                 350                 355                 360

 Lys Gly Asp Lys Ala Gln Ile Glu Lys Arg Ile Gln Glu Ile Ile
                 365                 370                 375

 Glu Gln Leu Asp Val Thr Thr Ser Glu Tyr Glu Lys Glu Lys Leu
                 380                 385                 390

 Asn Glu Arg Leu Ala Lys Leu Ser Asp Gly Val Ala Val Leu Lys
                 395                 400                 405

 Val Gly Gly Thr Ser Asp Val Glu Val Asn Glu Lys Lys Asp Arg
                 410                 415                 420

 Val Thr Asp Ala Leu Asn Ala Thr Arg Ala Ala Val Glu Glu Gly
                 425                 430                 435

 Ile Val Leu Gly Gly Gly Cys Ala Leu Leu Arg Cys Ile Pro Ala
                 440                 445                 450

 Leu Asp Ser Leu Thr Pro Ala Asn Glu Asp Gln Lys Ile Gly Ile
                 455                 460                 465

 Glu Ile Ile Lys Arg Thr Leu Lys Ile Pro Ala Met Thr Ile Ala
                 470                 475                 480

 Lys Asn Ala Gly Val Glu Gly Ser Leu Ile Val Glu Lys Ile Met
                 485                 490                 495

 Gln Ser Ser Ser Glu Val Gly Tyr Asp Ala Met Ala Gly Asp Phe
                 500                 505                 510

 Val Asn Met Val Glu Lys Gly Ile Ile Asp Pro Thr Lys Val Val
                 515                 520                 525

 Arg Thr Ala Leu Leu Asp Ala Ala Gly Val Ala Ser Leu Leu Thr
                 530                 535                 540

 Thr Ala Glu Val Val Val Thr Glu Ile Pro Lys Glu Glu Lys Asp
                 545                 550                 555

 Pro Gly Met Gly Ala Met Gly Gly Met Gly Gly Gly Met Gly Gly
                 560                 565                 570

 Gly Met Phe


<210> 89
<211> 632
<212> DNA
<213> Homo sapien

<400> 89
 ctctcggctt tcggctcgga ggaggccaag gtgcaacttc cttcggtcgt 50

 cccgaatccg ggttcatccg acaccagccg cctccaccat gccgccgaag 100

 ttcgacccca acgagatcaa agtcgtatac ctgaggtgca ccggaggtga 150

 agtcggtgcc acttctgccc tggcccccaa gatcggcccc ctgggtctgt 200

 ctccaaaaaa agttggtgat gacattgcca aggcaacggg tgactggaag 250

 ggcctgagga ttacagtgaa actgaccatt cagaacagac aggcccagat 300

 tgaggtggtg ccttctgcct ctgccctgat catcaaagcc ctcaaggaac 350

 caccaagaga cagaaagaaa cagaaaaaca ttaaacacag tgggaatatc 400

 acttttgatg agattgtcaa cattgctcga cagatgcggc accgatcctt 450

 agccagagaa ctctctggaa ccattaaaga gatcctgggg actgcccagt 500

 cagtgggctg taatgttgat ggccgccatc ctcatgacat catcgatgac 550

 atcaacagtg gtgctgtgga atgcccagcc agttaagcac aaaggaaaac 600

 atttcaataa aggatcattt gacaactggt ga 632

<210> 90
<211> 165
<212> PRT
<213> Homo sapien

<400> 90
 Met Pro Pro Lys Phe Asp Pro Asn Glu Ile Lys Val Val Tyr Leu
   1               5                  10                  15

 Arg Cys Thr Gly Gly Glu Val Gly Ala Thr Ser Ala Leu Ala Pro
                  20                  25                  30

 Lys Ile Gly Pro Leu Gly Leu Ser Pro Lys Lys Val Gly Asp Asp
                  35                  40                  45

 Ile Ala Lys Ala Thr Gly Asp Trp Lys Gly Leu Arg Ile Thr Val
                  50                  55                  60

 Lys Leu Thr Ile Gln Asn Arg Gln Ala Gln Ile Glu Val Val Pro
                  65                  70                  75

 Ser Ala Ser Ala Leu Ile Ile Lys Ala Leu Lys Glu Pro Pro Arg
                  80                  85                  90

 Asp Arg Lys Lys Gln Lys Asn Ile Lys His Ser Gly Asn Ile Thr
                  95                 100                 105

 Phe Asp Glu Ile Val Asn Ile Ala Arg Gln Met Arg His Arg Ser
                 110                 115                 120

 Leu Ala Arg Glu Leu Ser Gly Thr Ile Lys Glu Ile Leu Gly Thr
                 125                 130                 135

 Ala Gln Ser Val Gly Cys Asn Val Asp Gly Arg His Pro His Asp
                 140                 145                 150

 Ile Ile Asp Asp Ile Asn Ser Gly Ala Val Glu Cys Pro Ala Ser
                 155                 160                 165

<210> 91
<211> 1322
<212> DNA
<213> Homo sapien

<400> 91
 tagcttggca cgaggctcgg gtcgttgtgg tgcgctgtct tcccgcttgc 50

 gtcagggacc tgcccgactc agtggccgcc atggcatcag atgaaggcaa 100

 actttttgtt ggagggctga gttttgacac caatgagcag tcgctggagc 150

 aggtcttctc aaagtacgga cagatctctg aagtggtggt tgtgaaagac 200

 agggagaccc agagatctcg gggatttggg tttgtcacct ttgagaacat 250

 tgacgacgct aaggatgcca tgatggccat gaatgggaag tctgtagatg 300

 gacggcagat ccgagtagac caggcaggca agtcgtcaga caaccgatcc 350

 cgtgggtacc gtggtggctc tgccgggggc cggggcttct tccgtggggg 400

 ccgaggacgg ggccgtgggt tctctagagg aggaggggac cgaggctatg 450

 gggggaaccg gttcgagtcc aggagtgggg gctacggagg ctccagagac 500

 tactatagca gccggagtca gagtggtggc tacagtgacc ggagctcggg 550

 cgggtcctac agagacagtt acgacagtta cgctacacac aacgagtaaa 600

 aacccttcct gctcaagatc gtccttccaa tggctgtgtg tttaaagatt 650

 gtgggagctt cgctgaacgt taatgtgtag taaatgcacc tccttgtatt 700

 cccactttcg tagtcatttc ggttctgatc ttgtcaaacc cagcctgacc 750

 gcttctgacg ccgggatggc ctcgttacta gacttttctt tttaaggaag 800

 tgctgttttt ttttgagggt tttcaaaaca ttttgaaaag catttacttt 850

 tttgaccacg agccatgagt tttcaaaaaa atcgggggtt gtgtgggttt 900

 ttggtttttg ttttagtttt tggttgcgtt gccttttttt tttagtgggg 950

 ttggccccat gaagtgggtg ccccactcac ttctctgaga tcgaacggac 1000

 tgtgaatccg ctctttgtcg gaagctgagc aagctgtggc ttttttccaa 1050

 ctccgtgtga cgtttctgag tgtagtgtgg taggacccgg cgggtgtgca 1100

 gcaactgccc tggagcccca gcccctgcgt ccatctgtgc tgtgcgcccc 1150

 acagtagacg tgcagacgtc cctgagaggt tcttgaagat gtttatttat 1200

 attgtccttt tttactggaa gacgtacgca tactccatcg atgttgtatt 1250

 tgcagtggct gaggaattct tgtacgcagt tttctttggc tttacgagcc 1300

 gattaaaaga ccgtgtgaaa tg 1322

<210> 92
<211> 172
<212> PRT
<213> Homo sapien

<400> 92
 Met Ala Ser Asp Glu Gly Lys Leu Phe Val Gly Gly Leu Ser Phe
   1               5                  10                  15

 Asp Thr Asn Glu Gln Ser Leu Glu Gln Val Phe Ser Lys Tyr Gly
                  20                  25                  30

 Gln Ile Ser Glu Val Val Val Val Lys Asp Arg Glu Thr Gln Arg
                  35                  40                  45

 Ser Arg Gly Phe Gly Phe Val Thr Phe Glu Asn Ile Asp Asp Ala
                  50                  55                  60

 Lys Asp Ala Met Met Ala Met Asn Gly Lys Ser Val Asp Gly Arg
                  65                  70                  75

 Gln Ile Arg Val Asp Gln Ala Gly Lys Ser Ser Asp Asn Arg Ser
                  80                  85                  90

 Arg Gly Tyr Arg Gly Gly Ser Ala Gly Gly Arg Gly Phe Phe Arg
                  95                 100                 105

 Gly Gly Arg Gly Arg Gly Arg Gly Phe Ser Arg Gly Gly Gly Asp
                 110                 115                 120

 Arg Gly Tyr Gly Gly Asn Arg Phe Glu Ser Arg Ser Gly Gly Tyr
                 125                 130                 135

 Gly Gly Ser Arg Asp Tyr Tyr Ser Ser Arg Ser Gln Ser Gly Gly
                 140                 145                 150

 Tyr Ser Asp Arg Ser Ser Gly Gly Ser Tyr Arg Asp Ser Tyr Asp
                 155                 160                 165

 Ser Tyr Ala Thr His Asn Glu
                 170

<210> 93
<211> 1322
<212> DNA
<213> Homo sapien

<400> 93
 tagcttggca cgaggctcgg gtcgttgtgg tgcgctgtct tcccgcttgc 50

 gtcagggacc tgcccgactc agtggccgcc atggcatcag atgaaggcaa 100

 actttttgtt ggagggctga gttttgacac caatgagcag tcgctggagc 150

 aggtcttctc aaagtacgga cagatctctg aagtggtggt tgtgaaagac 200

 agggagaccc agagatctcg gggatttggg tttgtcacct ttgagaacat 250

 tgacgacgct aaggatgcca tgatggccat gaatgggaag tctgtagatg 300

 gacggcagat ccgagtagac caggcaggca agtcgtcaga caaccgatcc 350

 cgtgggtacc gtggtggctc tgccgggggc cggggcttct tccgtggggg 400

 ccgaggacgg ggccgtgggt tctctagagg aggaggggac cgaggctatg 450

 gggggaaccg gttcgagtcc aggagtgggg gctacggagg ctccagagac 500

 tactatagca gccggagtca gagtggtggc tacagtgacc ggagctcggg 550

 cgggtcctac agagacagtt acgacagtta cgctacacac aacgagtaaa 600

 aacccttcct gctcaagatc gtccttccaa tggctgtgtg tttaaagatt 650

 gtgggagctt cgctgaacgt taatgtgtag taaatgcacc tccttgtatt 700

 cccactttcg tagtcatttc ggttctgatc ttgtcaaacc cagcctgacc 750

 gcttctgacg ccgggatggc ctcgttacta gacttttctt tttaaggaag 800

 tgctgttttt ttttgagggt tttcaaaaca ttttgaaaag catttacttt 850

 tttgaccacg agccatgagt tttcaaaaaa atcgggggtt gtgtgggttt 900

 ttggtttttg ttttagtttt tggttgcgtt gccttttttt tttagtgggg 950

 ttggccccat gaagtgggtg ccccactcac ttctctgaga tcgaacggac 1000

 tgtgaatccg ctctttgtcg gaagctgagc aagctgtggc ttttttccaa 1050

 ctccgtgtga cgtttctgag tgtagtgtgg taggacccgg cgggtgtgca 1100

 gcaactgccc tggagcccca gcccctgcgt ccatctgtgc tgtgcgcccc 1150

 acagtagacg tgcagacgtc cctgagaggt tcttgaagat gtttatttat 1200

 attgtccttt tttactggaa gacgtacgca tactccatcg atgttgtatt 1250

 tgcagtggct gaggaattct tgtacgcagt tttctttggc tttacgagcc 1300

 gattaaaaga ccgtgtgaaa tg 1322

<210> 94
<211> 172
<212> PRT
<213> Homo sapien

<400> 94
 Met Ala Ser Asp Glu Gly Lys Leu Phe Val Gly Gly Leu Ser Phe
   1               5                  10                  15

 Asp Thr Asn Glu Gln Ser Leu Glu Gln Val Phe Ser Lys Tyr Gly
                  20                  25                  30

 Gln Ile Ser Glu Val Val Val Val Lys Asp Arg Glu Thr Gln Arg
                  35                  40                  45

 Ser Arg Gly Phe Gly Phe Val Thr Phe Glu Asn Ile Asp Asp Ala
                  50                  55                  60

 Lys Asp Ala Met Met Ala Met Asn Gly Lys Ser Val Asp Gly Arg
                  65                  70                  75

 Gln Ile Arg Val Asp Gln Ala Gly Lys Ser Ser Asp Asn Arg Ser
                  80                  85                  90

 Arg Gly Tyr Arg Gly Gly Ser Ala Gly Gly Arg Gly Phe Phe Arg
                  95                 100                 105

 Gly Gly Arg Gly Arg Gly Arg Gly Phe Ser Arg Gly Gly Gly Asp
                 110                 115                 120

 Arg Gly Tyr Gly Gly Asn Arg Phe Glu Ser Arg Ser Gly Gly Tyr
                 125                 130                 135

 Gly Gly Ser Arg Asp Tyr Tyr Ser Ser Arg Ser Gln Ser Gly Gly
                 140                 145                 150

 Tyr Ser Asp Arg Ser Ser Gly Gly Ser Tyr Arg Asp Ser Tyr Asp
                 155                 160                 165

 Ser Tyr Ala Thr His Asn Glu
                 170

<210> 95
<211> 1863
<212> DNA
<213> Homo sapien

<400> 95
 gttccaaggt ttgcggcccg gtctcggaga agaggggaga gtggagggcc 50

 gctgaataag cttccaaaat gatgcccaca ccagttatcc tattgaaaga 100

 ggggactgat agctcccaag gcatccccca gcttgtgagt aacatcagtg 150

 cctgccaggt gattgctgag gctgtaagaa ctaccctggg tccccgtggc 200

 atggacaagc ttattgtaga tggcagaggc aaagcaacaa tttctaatga 250

 tggggccaca attctgaaac ttcttgatgt tgtccatcct gcagcaaaga 300

 ctttggtaga cattgccaaa tcccaagatg ctgaggtggg tgatggcacc 350

 acctcagtga ccttgctggc tgcagagttt ctgaagcagg tgaaacccta 400

 tgtggaggaa ggtttacacc cccagatcat cattcgagct ttccgcacag 450

 ccacccagct ggcagttaac aagatcaaag agattgctgt gaccgtgaag 500

 aaggcagata aagtggagca gaggaagctg ctggaaaagt gtgccatgac 550

 cgctctgagc tccaagctga tctcccagca gaaagctttc tttgctaaga 600

 tggtggtgga tgcagtgatg atgctcgatg atttgctgca gcttaaaatg 650

 attggaatca agaaggtaca gggtggagcc ctcgaggatt ctcagctggt 700

 agctggtgtt gcattcaaga agactttctc ttacgctggg tttgaaatgc 750

 aacccaaaaa gtaccacaat cccaagattg cccttttgaa tgtcgagctc 800

 gagttgaaag ctgagaaaga caatgctgag ataagagtcc acacagttga 850

 ggattatcag gcaattgttg atgctgagtg gaacattctc tatgacaagt 900

 tagagaagat ccatcattct ggagccaaag ttgtcttgtc caaactcccc 950

 attggggatg tggccaccca gtactttgct gacagggaca tgttctgtgc 1000

 tggccgagta cctgaggagg atctgaagag gacaatgatg gcctgtggag 1050

 gctcaatcca gaccagtgtg aatgctctgt cagcagatgt gctgggtcga 1100

 tgccaggtgt ttgaagagac ccagattgga ggcgagaggt acaatttttt 1150

 tactggctgc cccaaggcca agacatgcac cttcattctc cgtggcggcg 1200

 ccgagcagtt tatggaggag acagagcggt ccctgcatga tgccatcatg 1250

 atcgtcagga gggccatcaa gaatgattca gtggtggctg gtggcggggc 1300

 cattgagatg gaactctcca agtacctgcg ggattactca aggactattc 1350

 caggaaaaca gcagctgttg attggggctt atgccaaggc cttggagatt 1400

 atcccacgcc agctgtgtga caatgctggc tttgatgcca caaacattct 1450

 caacaagctg cgggctcggc atgcccaggg gggtacatgg tatggagtag 1500

 acatcaacaa cgaggacatt gctgacaact ttgaagcttt cgtgtgggag 1550

 ccagctatgg tgcggatcaa tgcgctgaca gcagcctctg aggctgcgtg 1600

 cctgatcgtg tctgtagatg aaaccatcaa gaacccccgc tcgactgtgg 1650

 atgctcccac agcagcaggc cggggccgtg gtcgtggccg cccccactga 1700

 gaggcacccc acccatcaca tggctggctg gctgctgggt gcacttaccc 1750

 tccttggctt ggttacttca ttttacaagg aaggggtagt aattggccca 1800

 ctctcttctt actggaggct atttaaataa aatgtaagac ttcaaaaaaa 1850

 aaaaaaaaaa aaa 1863

<210> 96
<211> 543
<212> PRT
<213> Homo sapien

<400> 96
 Met Met Pro Thr Pro Val Ile Leu Leu Lys Glu Gly Thr Asp Ser
   1               5                  10                  15

 Ser Gln Gly Ile Pro Gln Leu Val Ser Asn Ile Ser Ala Cys Gln
                  20                  25                  30

 Val Ile Ala Glu Ala Val Arg Thr Thr Leu Gly Pro Arg Gly Met
                  35                  40                  45

 Asp Lys Leu Ile Val Asp Gly Arg Gly Lys Ala Thr Ile Ser Asn
                  50                  55                  60

 Asp Gly Ala Thr Ile Leu Lys Leu Leu Asp Val Val His Pro Ala
                  65                  70                  75

 Ala Lys Thr Leu Val Asp Ile Ala Lys Ser Gln Asp Ala Glu Val
                  80                  85                  90

 Gly Asp Gly Thr Thr Ser Val Thr Leu Leu Ala Ala Glu Phe Leu
                  95                 100                 105

 Lys Gln Val Lys Pro Tyr Val Glu Glu Gly Leu His Pro Gln Ile
                 110                 115                 120

 Ile Ile Arg Ala Phe Arg Thr Ala Thr Gln Leu Ala Val Asn Lys
                 125                 130                 135

 Ile Lys Glu Ile Ala Val Thr Val Lys Lys Ala Asp Lys Val Glu
                 140                 145                 150

 Gln Arg Lys Leu Leu Glu Lys Cys Ala Met Thr Ala Leu Ser Ser
                 155                 160                 165

 Lys Leu Ile Ser Gln Gln Lys Ala Phe Phe Ala Lys Met Val Val
                 170                 175                 180

 Asp Ala Val Met Met Leu Asp Asp Leu Leu Gln Leu Lys Met Ile
                 185                 190                 195

 Gly Ile Lys Lys Val Gln Gly Gly Ala Leu Glu Asp Ser Gln Leu
                 200                 205                 210

 Val Ala Gly Val Ala Phe Lys Lys Thr Phe Ser Tyr Ala Gly Phe
                 215                 220                 225

 Glu Met Gln Pro Lys Lys Tyr His Asn Pro Lys Ile Ala Leu Leu
                 230                 235                 240

 Asn Val Glu Leu Glu Leu Lys Ala Glu Lys Asp Asn Ala Glu Ile
                 245                 250                 255

 Arg Val His Thr Val Glu Asp Tyr Gln Ala Ile Val Asp Ala Glu
                 260                 265                 270

 Trp Asn Ile Leu Tyr Asp Lys Leu Glu Lys Ile His His Ser Gly
                 275                 280                 285

 Ala Lys Val Val Leu Ser Lys Leu Pro Ile Gly Asp Val Ala Thr
                 290                 295                 300

 Gln Tyr Phe Ala Asp Arg Asp Met Phe Cys Ala Gly Arg Val Pro
                 305                 310                 315

 Glu Glu Asp Leu Lys Arg Thr Met Met Ala Cys Gly Gly Ser Ile
                 320                 325                 330

 Gln Thr Ser Val Asn Ala Leu Ser Ala Asp Val Leu Gly Arg Cys
                 335                 340                 345

 Gln Val Phe Glu Glu Thr Gln Ile Gly Gly Glu Arg Tyr Asn Phe
                 350                 355                 360

 Phe Thr Gly Cys Pro Lys Ala Lys Thr Cys Thr Phe Ile Leu Arg
                 365                 370                 375

 Gly Gly Ala Glu Gln Phe Met Glu Glu Thr Glu Arg Ser Leu His
                 380                 385                 390

 Asp Ala Ile Met Ile Val Arg Arg Ala Ile Lys Asn Asp Ser Val
                 395                 400                 405

 Val Ala Gly Gly Gly Ala Ile Glu Met Glu Leu Ser Lys Tyr Leu
                 410                 415                 420

 Arg Asp Tyr Ser Arg Thr Ile Pro Gly Lys Gln Gln Leu Leu Ile
                 425                 430                 435

 Gly Ala Tyr Ala Lys Ala Leu Glu Ile Ile Pro Arg Gln Leu Cys
                 440                 445                 450

 Asp Asn Ala Gly Phe Asp Ala Thr Asn Ile Leu Asn Lys Leu Arg
                 455                 460                 465

 Ala Arg His Ala Gln Gly Gly Thr Trp Tyr Gly Val Asp Ile Asn
                 470                 475                 480

 Asn Glu Asp Ile Ala Asp Asn Phe Glu Ala Phe Val Trp Glu Pro
                 485                 490                 495

 Ala Met Val Arg Ile Asn Ala Leu Thr Ala Ala Ser Glu Ala Ala
                 500                 505                 510

 Cys Leu Ile Val Ser Val Asp Glu Thr Ile Lys Asn Pro Arg Ser
                 515                 520                 525

 Thr Val Asp Ala Pro Thr Ala Ala Gly Arg Gly Arg Gly Arg Gly
                 530                 535                 540

 Arg Pro His


<210> 97
<211> 737
<212> DNA
<213> Mus musculus

<400> 97
 ggagtttcgc cgccgcagtc ttcgccacca tgccgcccta caccgtggtc 50

 tatttcccag ttcgaggccg ctgcgcggcc ctgcgcatgc tgctggcaga 100

 tcagggccag agctggaagg aggaggtggt gaccgtggag acgtggcagg 150

 agggctcact caaagcctcc tgcctatacg ggcagctccc caagttccag 200

 gacggagacc tcaccctgta ccagtccaat accatcctgc gtcacctggg 250

 ccgcaccctt gggctctatg ggaaggacca gcaggaggca gccctggtgg 300

 acatggtgaa tgacggcgtg gaggacctcc gctgcaaata catctccctc 350

 atctacacca actatgaggc gggcaaggat gactatgtga aggcactgcc 400

 cgggcaactg aagccttttg agaccctgct gtcccagaac cagggaggca 450

 agaccttcat tgtgggagac cagatctcct tcgctgacta caacctgctg 500

 gacttgctgc tgatccatga ggtcctagcc cctggctgcc tggatgcgtt 550

 ccccctgctc tcagcatatg tggggcgcct cagcgcccgg cccaagctca 600

 aggccttcct ggcctcccct gagtacgtga acctccccat caatggcaac 650

 gggaaacagt gagggttggg gggactctga gcgggaggca gagtttgcct 700

 tcctttctcc aggaccaata aaatttctaa gagagct 737

<210> 98
<211> 210
<212> PRT
<213> Mus musculus

<400> 98
 Met Pro Pro Tyr Thr Val Val Tyr Phe Pro Val Arg Gly Arg Cys
   1               5                  10                  15

 Ala Ala Leu Arg Met Leu Leu Ala Asp Gln Gly Gln Ser Trp Lys
                  20                  25                  30

 Glu Glu Val Val Thr Val Glu Thr Trp Gln Glu Gly Ser Leu Lys
                  35                  40                  45

 Ala Ser Cys Leu Tyr Gly Gln Leu Pro Lys Phe Gln Asp Gly Asp
                  50                  55                  60

 Leu Thr Leu Tyr Gln Ser Asn Thr Ile Leu Arg His Leu Gly Arg
                  65                  70                  75

 Thr Leu Gly Leu Tyr Gly Lys Asp Gln Gln Glu Ala Ala Leu Val
                  80                  85                  90

 Asp Met Val Asn Asp Gly Val Glu Asp Leu Arg Cys Lys Tyr Ile
                  95                 100                 105

 Ser Leu Ile Tyr Thr Asn Tyr Glu Ala Gly Lys Asp Asp Tyr Val
                 110                 115                 120

 Lys Ala Leu Pro Gly Gln Leu Lys Pro Phe Glu Thr Leu Leu Ser
                 125                 130                 135

 Gln Asn Gln Gly Gly Lys Thr Phe Ile Val Gly Asp Gln Ile Ser
                 140                 145                 150

 Phe Ala Asp Tyr Asn Leu Leu Asp Leu Leu Leu Ile His Glu Val
                 155                 160                 165

 Leu Ala Pro Gly Cys Leu Asp Ala Phe Pro Leu Leu Ser Ala Tyr
                 170                 175                 180

 Val Gly Arg Leu Ser Ala Arg Pro Lys Leu Lys Ala Phe Leu Ala
                 185                 190                 195

 Ser Pro Glu Tyr Val Asn Leu Pro Ile Asn Gly Asn Gly Lys Gln
                 200                 205                 210

<210> 99
<211> 4552
<212> DNA
<213> Homo sapien

<400> 99
 agcgcccgcc gcgtccgggg ccggctggtg cgcgagacgc cgccgagagt 50

 tgtgaagggc gcgggtgggg ggcgctgccg gcctcgtggg tacgttcgtg 100

 ccgcgtctgt cccagagctg gggccgcagg agcggaggca agaggggcac 150

 tatggcagac aaagttagga ggcagaggcc gaggaggcga gtctgttggg 200

 ccttggtggc tgtgctcttg gcagacctgt tggcactgag tgatacactg 250

 gcagtgatgt ctgtggacct gggcagtgag tccatgaagg tggccattgt 300

 caaacctgga gtgcccatgg aaattgtctt gaataaggaa tctcggagga 350

 aaacaccggt gatcgtgacc ctgaaagaaa atgaaagatt ctttggagac 400

 agtgcagcaa gcatggcgat taagaatcca aaggctacgc tacgttactt 450

 ccagcacctc ctggggaagc aggcagataa cccccatgta gctctttacc 500

 aggcccgctt cccggagcac gagctgactt tcgacccaca gaggcagact 550

 gtgcactttc agatcagctc gcagctgcag ttctcacctg aggaagtgtt 600

 gggcatggtt ctcaattatt ctcgttctct agctgaagat tttgcagagc 650

 agcccatcaa ggatgcagtg atcaccgtgc cagtcttctt caaccaggcc 700

 gagcgccgag ctgtgctgca ggctgctcgt atggctggcc tcaaagtgct 750

 gcagctcatc aatgacaaca ccgccactgc cctcagctat ggtgtcttcc 800

 gccggaaaga tattaacacc actgcccaga atatcatgtt ctatgacatg 850

 ggctcaggca gcaccgtatg caccattgtg acctaccaga tggtgaagac 900

 taaggaagct gggatgcagc cacagctgca gatccgggga gtaggatttg 950

 accgtaccct ggggggcctg gagatggagc tccggcttcg agaacgcctg 1000

 gctgggcttt tcaatgagca gcgcaagggt cagagagcaa aggatgtgcg 1050

 ggagaacccg cgtgccatgg ccaagctgct gcgtgaggct aatcggctca 1100

 aaaccgtcct cagtgccaac gctgaccaca tggcacagat tgaaggcctg 1150

 atggatgatg tggacttcaa ggcaaaagtg actcgtgtgg aatttgagga 1200

 gttgtgtgca gacttgtttg agcgggtgcc tgggcctgta cagcaggccc 1250

 tccagagtgc cgaaatgagt ctggatgaga ttgagcaggt gatcctggtg 1300

 ggtggggcca ctcgggtccc cagagttcag gaggtgctgc tgaaggccgt 1350

 gggcaaggag gagctgggga agaacatcaa tgcagatgaa gcagccgcca 1400

 tgggggcagt gtaccaggca gctgcgctca gcaaagcctt taaagtgaag 1450

 ccatttgtcg tccgagatgc agtggtctac cccatcctgg tggagttcac 1500

 gagggaggtg gaggaggagc ctgggattca cagcctgaag cacaataaac 1550

 gggtactctt ctctcggatg gggccctacc ctcaacgcaa agtcatcacc 1600

 tttaaccgct acagccatga tttcaacttc cacatcaact acggcgacct 1650

 gggcttcctg gggcctgaag atcttcgggt atttggctcc cagaatctga 1700

 ccacagtgaa gctaaaaggg gtgggtgaca gcttcaagaa gtatcctgac 1750

 tacgagtcca agggcatcaa ggctcacttc aacctggatg agagtggcgt 1800

 gctcagtcta gacagggtgg agtctgtatt tgagacactg gtagaggaca 1850

 gcgcagaaga ggaatctact ctcaccaaac ttggcaacac catttccagc 1900

 ctgtttggag gcggtaccac accagatgcc aaggagaatg gtactgatac 1950

 tgtccaggag gaagaggaga gccctgcaga ggggagcaag gacgagcctg 2000

 gggagcaggt ggagctcaag gaggaagctg aggccccagt ggaggatggc 2050

 tctcagcccc caccccctga acctaaggga gatgcaaccc ctgagggaga 2100

 aaaggccaca gaaaaagaaa atggggacaa gtctgaggcc cagaaaccaa 2150

 gtgagaaggc agaggcaggg cctgagggcg tcgctccagc cccagaggga 2200

 gagaagaagc agaagcccgc caggaagcgg cgaatggtag aggagatcgg 2250

 ggtggagctg gttgttctgg acctgcctga cttgccagag gataagctgg 2300

 ctcagtcggt gcagaaactt caggacttga cactccgaga cctggagaag 2350

 caggaacggg aaaaagctgc caacagcttg gaagcgttca tatttgagac 2400

 ccaggacaag ctgtaccagc ccgagtacca ggaagtgtcc acagaggagc 2450

 agcgtgagga gatctctggg aagctcagcg ccgcatccac ctggctggag 2500

 gatgagggtg ttggagccac cacagtgatg ttgaaggaga agctggctga 2550

 gctgaggaag ctgtgccaag ggctgttttt tcgggtagag gagcgcaaga 2600

 agtggcccga acggctgtct gccctcgata atctcctcaa ccattccagc 2650

 atgttcctca agggggcccg gctcatccca gagatggacc agatcttcac 2700

 tgaggtggag atgacaacgt tagagaaagt catcaatgag acctgggcct 2750

 ggaagaatgc aactctggcc gagcaggcta agctgcccgc cacagagaag 2800

 cctgtgttgc tctcaaaaga cattgaagct aagatgatgg ccctggaccg 2850

 agaggtgcag tatctgctca ataaggccaa gtttaccaag ccccggcccc 2900

 ggcctaagga caagaatggg acccgggcag agccacccct caatgccagt 2950

 gccagtgacc agggggagaa ggtcatccct ccagcaggcc agactgaaga 3000

 tgcagagccc atttcagaac ctgagaaagt agagactgga tccgagccag 3050

 gagacactga gcctttggag ttaggaggtc ctggagcaga acctgaacag 3100

 aaagaacaat cgacaggaca gaagcggcct ttgaagaacg acgaactata 3150

 acccccacct ctgttttccc cattcatctc cacccccttc ccccaccact 3200

 tctatttatt taacatcgag ggttggggga ggggttggtc ctgccctcgg 3250

 ctggagttcc tttctcaccc ctgtgatttg gaggtgtgga gaaggggaag 3300

 ggagggacag ctcactggtt ccttctgcag tacctctgtg gttaaaaatg 3350

 gaaactgttc tcctccccag ccccactccc tgttccctac ccatataggc 3400

 cctaaatttg ggaaaaatca ctattaattt ctgaatcctt tgcctgtggg 3450

 taggaagaga atggctgcca gtggctgatg ggtcccggtg atgggaaggg 3500

 tatcaggttg ctggggagtt tccactcttc tctggtgatt gttccttccc 3550

 tcccttcctc tcccaccatg cgatgagcat cctttcaggc cagtgtctgc 3600

 agagcctcag ttaccaggtt tggtttctga gtgcctatct gtgctctttc 3650

 ctccctctgc gggcttctct tgctctgagc ctcccttccc cattcccatg 3700

 cagctccttt ccccctgggt ttccttggct tcctgcagca aattgggcag 3750

 ttctctgccc cttgcctaaa agcctgtacc tctggattgg cggaagtaaa 3800

 tctggaagga ttctcactcg tatttcccac ccctagtggc cagaggaggg 3850

 aggggcacag tgaagaaggg agcccaccac ctctccgaag aggaaagcca 3900

 cgtagagtgg ttggcatggg gtgccagcat cgtgcaagct ctgtcataat 3950

 ctgcatcttc ccagcagcct ggtaccccag gttcctgtaa ctccctgcct 4000

 cctcctctct tctgctgttc tgctcctccc agacagagcc tttccctcac 4050

 cccctgaccc cctgggctga ccaaaatgtg ctttctactg tgagtcccta 4100

 tcccaagatc ctggggaaag gagagaccat ggtgtgaatg tagagatgcc 4150

 acctccctct ctctgaggca ggcctgtgga tgaaggagga gggtcagggc 4200

 tggccttcct ctgtgcatca ctctgctagg ttgggggccc ccgacccacc 4250

 atacctacgc ctagggagcc cgtcctccag tattccgtct gtagcaggag 4300

 ctagggctgc tgcctcagct ccaagacaag aatgaacctg gctgtgtcag 4350

 tcattttgtc ttttcctttt tttttttttg ccacattggc agagatggga 4400

 cctaagggtc ccacccctca ccccaccccc acctcttctg tatgtttgaa 4450

 ttctttcagt agctgttgat gctggttgga caggtttgag tcaaattgta 4500

 ctttgctcca ttgttaattg agaaactgtt tcaataaaat attcttttct 4550

 ac 4552

<210> 100
<211> 999
<212> PRT
<213> Homo sapien

<400> 100
 Met Ala Asp Lys Val Arg Arg Gln Arg Pro Arg Arg Arg Val Cys
   1               5                  10                  15

 Trp Ala Leu Val Ala Val Leu Leu Ala Asp Leu Leu Ala Leu Ser
                  20                  25                  30

 Asp Thr Leu Ala Val Met Ser Val Asp Leu Gly Ser Glu Ser Met
                  35                  40                  45

 Lys Val Ala Ile Val Lys Pro Gly Val Pro Met Glu Ile Val Leu
                  50                  55                  60

 Asn Lys Glu Ser Arg Arg Lys Thr Pro Val Ile Val Thr Leu Lys
                  65                  70                  75

 Glu Asn Glu Arg Phe Phe Gly Asp Ser Ala Ala Ser Met Ala Ile
                  80                  85                  90

 Lys Asn Pro Lys Ala Thr Leu Arg Tyr Phe Gln His Leu Leu Gly
                  95                 100                 105

 Lys Gln Ala Asp Asn Pro His Val Ala Leu Tyr Gln Ala Arg Phe
                 110                 115                 120

 Pro Glu His Glu Leu Thr Phe Asp Pro Gln Arg Gln Thr Val His
                 125                 130                 135

 Phe Gln Ile Ser Ser Gln Leu Gln Phe Ser Pro Glu Glu Val Leu
                 140                 145                 150

 Gly Met Val Leu Asn Tyr Ser Arg Ser Leu Ala Glu Asp Phe Ala
                 155                 160                 165

 Glu Gln Pro Ile Lys Asp Ala Val Ile Thr Val Pro Val Phe Phe
                 170                 175                 180

 Asn Gln Ala Glu Arg Arg Ala Val Leu Gln Ala Ala Arg Met Ala
                 185                 190                 195

 Gly Leu Lys Val Leu Gln Leu Ile Asn Asp Asn Thr Ala Thr Ala
                 200                 205                 210

 Leu Ser Tyr Gly Val Phe Arg Arg Lys Asp Ile Asn Thr Thr Ala
                 215                 220                 225

 Gln Asn Ile Met Phe Tyr Asp Met Gly Ser Gly Ser Thr Val Cys
                 230                 235                 240

 Thr Ile Val Thr Tyr Gln Met Val Lys Thr Lys Glu Ala Gly Met
                 245                 250                 255

 Gln Pro Gln Leu Gln Ile Arg Gly Val Gly Phe Asp Arg Thr Leu
                 260                 265                 270

 Gly Gly Leu Glu Met Glu Leu Arg Leu Arg Glu Arg Leu Ala Gly
                 275                 280                 285

 Leu Phe Asn Glu Gln Arg Lys Gly Gln Arg Ala Lys Asp Val Arg
                 290                 295                 300

 Glu Asn Pro Arg Ala Met Ala Lys Leu Leu Arg Glu Ala Asn Arg
                 305                 310                 315

 Leu Lys Thr Val Leu Ser Ala Asn Ala Asp His Met Ala Gln Ile
                 320                 325                 330

 Glu Gly Leu Met Asp Asp Val Asp Phe Lys Ala Lys Val Thr Arg
                 335                 340                 345

 Val Glu Phe Glu Glu Leu Cys Ala Asp Leu Phe Glu Arg Val Pro
                 350                 355                 360

 Gly Pro Val Gln Gln Ala Leu Gln Ser Ala Glu Met Ser Leu Asp
                 365                 370                 375

 Glu Ile Glu Gln Val Ile Leu Val Gly Gly Ala Thr Arg Val Pro
                 380                 385                 390

 Arg Val Gln Glu Val Leu Leu Lys Ala Val Gly Lys Glu Glu Leu
                 395                 400                 405

 Gly Lys Asn Ile Asn Ala Asp Glu Ala Ala Ala Met Gly Ala Val
                 410                 415                 420

 Tyr Gln Ala Ala Ala Leu Ser Lys Ala Phe Lys Val Lys Pro Phe
                 425                 430                 435

 Val Val Arg Asp Ala Val Val Tyr Pro Ile Leu Val Glu Phe Thr
                 440                 445                 450

 Arg Glu Val Glu Glu Glu Pro Gly Ile His Ser Leu Lys His Asn
                 455                 460                 465

 Lys Arg Val Leu Phe Ser Arg Met Gly Pro Tyr Pro Gln Arg Lys
                 470                 475                 480

 Val Ile Thr Phe Asn Arg Tyr Ser His Asp Phe Asn Phe His Ile
                 485                 490                 495

 Asn Tyr Gly Asp Leu Gly Phe Leu Gly Pro Glu Asp Leu Arg Val
                 500                 505                 510

 Phe Gly Ser Gln Asn Leu Thr Thr Val Lys Leu Lys Gly Val Gly
                 515                 520                 525

 Asp Ser Phe Lys Lys Tyr Pro Asp Tyr Glu Ser Lys Gly Ile Lys
                 530                 535                 540

 Ala His Phe Asn Leu Asp Glu Ser Gly Val Leu Ser Leu Asp Arg
                 545                 550                 555

 Val Glu Ser Val Phe Glu Thr Leu Val Glu Asp Ser Ala Glu Glu
                 560                 565                 570

 Glu Ser Thr Leu Thr Lys Leu Gly Asn Thr Ile Ser Ser Leu Phe
                 575                 580                 585

 Gly Gly Gly Thr Thr Pro Asp Ala Lys Glu Asn Gly Thr Asp Thr
                 590                 595                 600

 Val Gln Glu Glu Glu Glu Ser Pro Ala Glu Gly Ser Lys Asp Glu
                 605                 610                 615

 Pro Gly Glu Gln Val Glu Leu Lys Glu Glu Ala Glu Ala Pro Val
                 620                 625                 630

 Glu Asp Gly Ser Gln Pro Pro Pro Pro Glu Pro Lys Gly Asp Ala
                 635                 640                 645

 Thr Pro Glu Gly Glu Lys Ala Thr Glu Lys Glu Asn Gly Asp Lys
                 650                 655                 660

 Ser Glu Ala Gln Lys Pro Ser Glu Lys Ala Glu Ala Gly Pro Glu
                 665                 670                 675

 Gly Val Ala Pro Ala Pro Glu Gly Glu Lys Lys Gln Lys Pro Ala
                 680                 685                 690

 Arg Lys Arg Arg Met Val Glu Glu Ile Gly Val Glu Leu Val Val
                 695                 700                 705

 Leu Asp Leu Pro Asp Leu Pro Glu Asp Lys Leu Ala Gln Ser Val
                 710                 715                 720

 Gln Lys Leu Gln Asp Leu Thr Leu Arg Asp Leu Glu Lys Gln Glu
                 725                 730                 735

 Arg Glu Lys Ala Ala Asn Ser Leu Glu Ala Phe Ile Phe Glu Thr
                 740                 745                 750

 Gln Asp Lys Leu Tyr Gln Pro Glu Tyr Gln Glu Val Ser Thr Glu
                 755                 760                 765

 Glu Gln Arg Glu Glu Ile Ser Gly Lys Leu Ser Ala Ala Ser Thr
                 770                 775                 780

 Trp Leu Glu Asp Glu Gly Val Gly Ala Thr Thr Val Met Leu Lys
                 785                 790                 795

 Glu Lys Leu Ala Glu Leu Arg Lys Leu Cys Gln Gly Leu Phe Phe
                 800                 805                 810

 Arg Val Glu Glu Arg Lys Lys Trp Pro Glu Arg Leu Ser Ala Leu
                 815                 820                 825

 Asp Asn Leu Leu Asn His Ser Ser Met Phe Leu Lys Gly Ala Arg
                 830                 835                 840

 Leu Ile Pro Glu Met Asp Gln Ile Phe Thr Glu Val Glu Met Thr
                 845                 850                 855

 Thr Leu Glu Lys Val Ile Asn Glu Thr Trp Ala Trp Lys Asn Ala
                 860                 865                 870

 Thr Leu Ala Glu Gln Ala Lys Leu Pro Ala Thr Glu Lys Pro Val
                 875                 880                 885

 Leu Leu Ser Lys Asp Ile Glu Ala Lys Met Met Ala Leu Asp Arg
                 890                 895                 900

 Glu Val Gln Tyr Leu Leu Asn Lys Ala Lys Phe Thr Lys Pro Arg
                 905                 910                 915

 Pro Arg Pro Lys Asp Lys Asn Gly Thr Arg Ala Glu Pro Pro Leu
                 920                 925                 930

 Asn Ala Ser Ala Ser Asp Gln Gly Glu Lys Val Ile Pro Pro Ala
                 935                 940                 945

 Gly Gln Thr Glu Asp Ala Glu Pro Ile Ser Glu Pro Glu Lys Val
                 950                 955                 960

 Glu Thr Gly Ser Glu Pro Gly Asp Thr Glu Pro Leu Glu Leu Gly
                 965                 970                 975

 Gly Pro Gly Ala Glu Pro Glu Gln Lys Glu Gln Ser Thr Gly Gln
                 980                 985                 990

 Lys Arg Pro Leu Lys Asn Asp Glu Leu
                 995

<210> 101
<211> 2002
<212> DNA
<213> Homo sapien

<400> 101
 aattccgcgg caaccgctcc ggcaacgcca accgctccgc tgcgcgcagg 50

 ctgggctgca ggctctcggc tgcagcgctg ggctggtgtg cagtggtgcg 100

 accacggctc acggcagcct cagccaccca gatgtaagcg atctggttcc 150

 cacctcagcc ttccgagtag tggatctagg atctggcttc caacatgtgg 200

 cagctctggg cctccctctg ctgcctgctg gtgttggcca atgcccggag 250

 caggccctct ttccatcccg tgtcggatga gctggtcaac tatgtcaaca 300

 aacggaatac cacgtggcag gccgggcaca acttctacaa cgtggacatg 350

 agctacttga agaggctatg tggtaccttc ctgggtgggc ccaagccacc 400

 ccagagagtt atgtttaccg aggacctgaa gctgcctgca agcttcgatg 450

 cacgggaaca atggccacag tgtcccacca tcaaagagat cagagaccag 500

 ggctcctgtg gctcctgctg ggccttcggg gctgtggaag ccatctctga 550

 ccgcatctgc atccacacca atgcgcacgt cagcgtggag gtgtcggcgg 600

 aggacctgct cacctgctgt ggcagcatgt gtggggacgg ctgtaatggt 650

 ggctatcctg ctgaagcttg gaacttctgg acaagaaaag gcctggtttc 700

 tggtggcctc tatgaatccc atgtagggtg cagaccgtac tccatccctc 750

 cctgtgagca ccacgtcaac ggctcccggc ccccatgcac gggggaggga 800

 gataccccca agtgtagcaa gatctgtgag cctggctaca gcccgaccta 850

 caaacaggac aagcactacg gatacaattc ctacagcgtc tccaatagcg 900

 agaaggacat catggccgag atctacaaaa acggccccgt ggagggagct 950

 ttctctgtgt attcggactt cctgctctac aagtcaggag tgtaccaaca 1000

 cgtcaccgga gagatgatgg gtggccatgc catccgcatc ctgggctggg 1050

 gagtggagaa tggcacaccc tactggctgg ttgccaactc ctggaacact 1100

 gactggggtg acaatggctt ctttaaaata ctcagaggac aggatcactg 1150

 cggaatcgaa tcagaagtgg tggctggaat tccacgcacc gatcagtact 1200

 gggaaaagat ctaatctgcc gtgggcctgt cgtgccagtc ctgggggcga 1250

 gatcggggta gaaagtcatt ttattcttta agttcacgta agatacaagt 1300

 ttcaggcagg gtctgaagga ctggattggc caaagtcctc caaggagacc 1350

 aagtcctggc tacatcccag cctgtggtta cagtgcagac aggccatgtg 1400

 agccaccgct gccagcacag agcgtccttc cccctgtaga ctagtgccgt 1450

 gggagtacct gctgcccagc tgctgtggcc ccctccgtga tccatccatc 1500

 tccagggagc aagacagaga cgcaggatgg aaagcggagt tcctaacagg 1550

 atgaaagttc ccccatcagt tcccccagta cctccaagca agtagctttc 1600

 cacatttgtc acagaaatca gaggagagat ggtgttggga gccctttgga 1650

 gaacgccagt ctccaggtcc ccctgcatct atcgagtttg caatgtcaca 1700

 acctctctga tcttgtgctc agcatgattc tttaatagaa gttttatttt 1750

 tcgtgcactc tgctaatcat gtgggtgagc cagtggaaca gcgggagcct 1800

 gtgctggttt gcagattgcc tcctaatgac gcggctcaaa aggaaaccaa 1850

 gtggtcagga gttgtttctg acccactgat ctctactacc acaaggaaaa 1900

 tagtttagga gaaaccagct tttactgttt ttgaaaaatt acagcttcac 1950

 cctgtcaagt taacaaggaa tgcctgtgcc aataaaaggt ttctccaact 2000

 tg 2002

<210> 102
<211> 339
<212> PRT
<213> Homo sapien

<400> 102
 Met Trp Gln Leu Trp Ala Ser Leu Cys Cys Leu Leu Val Leu Ala
   1               5                  10                  15

 Asn Ala Arg Ser Arg Pro Ser Phe His Pro Val Ser Asp Glu Leu
                  20                  25                  30

 Val Asn Tyr Val Asn Lys Arg Asn Thr Thr Trp Gln Ala Gly His
                  35                  40                  45

 Asn Phe Tyr Asn Val Asp Met Ser Tyr Leu Lys Arg Leu Cys Gly
                  50                  55                  60

 Thr Phe Leu Gly Gly Pro Lys Pro Pro Gln Arg Val Met Phe Thr
                  65                  70                  75

 Glu Asp Leu Lys Leu Pro Ala Ser Phe Asp Ala Arg Glu Gln Trp
                  80                  85                  90

 Pro Gln Cys Pro Thr Ile Lys Glu Ile Arg Asp Gln Gly Ser Cys
                  95                 100                 105

 Gly Ser Cys Trp Ala Phe Gly Ala Val Glu Ala Ile Ser Asp Arg
                 110                 115                 120

 Ile Cys Ile His Thr Asn Ala His Val Ser Val Glu Val Ser Ala
                 125                 130                 135

 Glu Asp Leu Leu Thr Cys Cys Gly Ser Met Cys Gly Asp Gly Cys
                 140                 145                 150

 Asn Gly Gly Tyr Pro Ala Glu Ala Trp Asn Phe Trp Thr Arg Lys
                 155                 160                 165

 Gly Leu Val Ser Gly Gly Leu Tyr Glu Ser His Val Gly Cys Arg
                 170                 175                 180

 Pro Tyr Ser Ile Pro Pro Cys Glu His His Val Asn Gly Ser Arg
                 185                 190                 195

 Pro Pro Cys Thr Gly Glu Gly Asp Thr Pro Lys Cys Ser Lys Ile
                 200                 205                 210

 Cys Glu Pro Gly Tyr Ser Pro Thr Tyr Lys Gln Asp Lys His Tyr
                 215                 220                 225

 Gly Tyr Asn Ser Tyr Ser Val Ser Asn Ser Glu Lys Asp Ile Met
                 230                 235                 240

 Ala Glu Ile Tyr Lys Asn Gly Pro Val Glu Gly Ala Phe Ser Val
                 245                 250                 255

 Tyr Ser Asp Phe Leu Leu Tyr Lys Ser Gly Val Tyr Gln His Val
                 260                 265                 270

 Thr Gly Glu Met Met Gly Gly His Ala Ile Arg Ile Leu Gly Trp
                 275                 280                 285

 Gly Val Glu Asn Gly Thr Pro Tyr Trp Leu Val Ala Asn Ser Trp
                 290                 295                 300

 Asn Thr Asp Trp Gly Asp Asn Gly Phe Phe Lys Ile Leu Arg Gly
                 305                 310                 315

 Gln Asp His Cys Gly Ile Glu Ser Glu Val Val Ala Gly Ile Pro
                 320                 325                 330

 Arg Thr Asp Gln Tyr Trp Glu Lys Ile
                 335

<210> 103
<211> 1996
<212> DNA
<213> Homo sapien

<400> 103
 tccggcaacg ccaaccgctc cgctgcgcgc aggctgggct gcaggctctc 50

 ggctgcagcg ctgggctggt gtgcagtggt gcgaccacgg ctcacggcag 100

 cctcagccac ccagatgtaa gcgatctggt tcccacctca gcctcccgag 150

 tagtggatct aggatccggc ttccaacatg tggcagctct gggcctccct 200

 ctgctgcctg ctggtgttgg ccaatgcccg gagcaggccc tctttccatc 250

 ccctgtcgga tgagctggtc aactatgtca acaaacggaa taccacgtgg 300

 caggccgggc acaacttcta caacgtggac atgagctact tgaagaggct 350

 atgtggtacc ttcctgggtg ggcccaagcc accccagaga gttatgttta 400

 ccgaggacct gaagctgcct gcaagcttcg atgcacggga acaatggcca 450

 cagtgtccca ccatcaaaga gatcagagac cagggctcct gtggctcctg 500

 ctgggccttc ggggctgtgg aagccatctc tgaccggatc tgcatccaca 550

 ccaatgcgca cgtcagcgtg gaggtgtcgg cggaggacct gctcacatgc 600

 tgtggcagca tgtgtgggga cggctgtaat ggtggctatc ctgctgaagc 650

 ttggaacttc tggacaagaa aaggcctggt ttctggtggc ctctatgaat 700

 cccatgtagg gtgcagaccg tactccatcc ctccctgtga gcaccacgtc 750

 aacggctccc ggcccccatg cacgggggag ggagataccc ccaagtgtag 800

 caagatctgt gagcctggct acagcccgac ctacaaacag gacaagcact 850

 acggatacaa ttcctacagc gtctccaata gcgagaagga catcatggcc 900

 gagatctaca aaaacggccc cgtggaggga gctttctctg tgtattcgga 950

 cttcctgctc tacaagtcag gagtgtacca acacgtcacc ggagagatga 1000

 tgggtggcca tgccatccgc atcctgggct ggggagtgga gaatggcaca 1050

 ccctactggc tggttgccaa ctcctggaac actgactggg gtgacaatgg 1100

 cttctttaaa atactcagag gacaggatca ctgtggaatc gaatcagaag 1150

 tggtggctgg aattccacgc accgatcagt actgggaaaa gatctaatct 1200

 gccgtgggcc tgtcgtgcca gtcctggggg cgagatcggg gtagaaatgc 1250

 attttattct ttaagttcac gtaagataca agtttcaggc agggtctgaa 1300

 ggactggatt ggccaaacat cagacctgtc ttccaaggag accaagtcct 1350

 ggctacatcc cagcctgtgg ttacagtgca gacaggccat gtgagccacc 1400

 gctgccagca cagagcgtcc ttccccctgt agactagtgc cgtgggagta 1450

 cctgctgccc agctgctgtg gccccctccg tgatccatcc atctccaggg 1500

 agcaagacag agacgcagga tggaaagcgg agttcctaac aggatgaaag 1550

 ttcccccatc agttccccca gtacctccaa gcaagtagct ttccacattt 1600

 gtcacagaaa tcagaggaga gatggtgttg ggagcccttt ggagaacgcc 1650

 agtctccagg tccccctgca tctatcgagt ttgcaatgtc acaacctctc 1700

 tgatcttgtg ctcagcatga ttctttaata gaagttttat ttttcgtgca 1750

 ctctgctaat catgtgggtg agccagtgga acagcgggag cctgtgctgg 1800

 tttgcagatt gcctcctaat gacgcggctc aaaaggaaac caagtggtca 1850

 ggagttgttt ctgacccact gatctctact accacaagga aaatagttta 1900

 ggagaaacca gcttttactg tttttgaaaa attacagctt caccctgtca 1950

 agttaacaag gaatgcctgt gccaataaaa ggtttctcca acttga 1996

<210> 104
<211> 339
<212> PRT
<213> Homo sapien

<400> 104
 Met Trp Gln Leu Trp Ala Ser Leu Cys Cys Leu Leu Val Leu Ala
   1               5                  10                  15

 Asn Ala Arg Ser Arg Pro Ser Phe His Pro Leu Ser Asp Glu Leu
                  20                  25                  30

 Val Asn Tyr Val Asn Lys Arg Asn Thr Thr Trp Gln Ala Gly His
                  35                  40                  45

 Asn Phe Tyr Asn Val Asp Met Ser Tyr Leu Lys Arg Leu Cys Gly
                  50                  55                  60

 Thr Phe Leu Gly Gly Pro Lys Pro Pro Gln Arg Val Met Phe Thr
                  65                  70                  75

 Glu Asp Leu Lys Leu Pro Ala Ser Phe Asp Ala Arg Glu Gln Trp
                  80                  85                  90

 Pro Gln Cys Pro Thr Ile Lys Glu Ile Arg Asp Gln Gly Ser Cys
                  95                 100                 105

 Gly Ser Cys Trp Ala Phe Gly Ala Val Glu Ala Ile Ser Asp Arg
                 110                 115                 120

 Ile Cys Ile His Thr Asn Ala His Val Ser Val Glu Val Ser Ala
                 125                 130                 135

 Glu Asp Leu Leu Thr Cys Cys Gly Ser Met Cys Gly Asp Gly Cys
                 140                 145                 150

 Asn Gly Gly Tyr Pro Ala Glu Ala Trp Asn Phe Trp Thr Arg Lys
                 155                 160                 165

 Gly Leu Val Ser Gly Gly Leu Tyr Glu Ser His Val Gly Cys Arg
                 170                 175                 180

 Pro Tyr Ser Ile Pro Pro Cys Glu His His Val Asn Gly Ser Arg
                 185                 190                 195

 Pro Pro Cys Thr Gly Glu Gly Asp Thr Pro Lys Cys Ser Lys Ile
                 200                 205                 210

 Cys Glu Pro Gly Tyr Ser Pro Thr Tyr Lys Gln Asp Lys His Tyr
                 215                 220                 225

 Gly Tyr Asn Ser Tyr Ser Val Ser Asn Ser Glu Lys Asp Ile Met
                 230                 235                 240

 Ala Glu Ile Tyr Lys Asn Gly Pro Val Glu Gly Ala Phe Ser Val
                 245                 250                 255

 Tyr Ser Asp Phe Leu Leu Tyr Lys Ser Gly Val Tyr Gln His Val
                 260                 265                 270

 Thr Gly Glu Met Met Gly Gly His Ala Ile Arg Ile Leu Gly Trp
                 275                 280                 285

 Gly Val Glu Asn Gly Thr Pro Tyr Trp Leu Val Ala Asn Ser Trp
                 290                 295                 300

 Asn Thr Asp Trp Gly Asp Asn Gly Phe Phe Lys Ile Leu Arg Gly
                 305                 310                 315

 Gln Asp His Cys Gly Ile Glu Ser Glu Val Val Ala Gly Ile Pro
                 320                 325                 330

 Arg Thr Asp Gln Tyr Trp Glu Lys Ile
                 335

<210> 105
<211> 618
<212> DNA
<213> Homo sapien

<400> 105
 cttttgcggg tggcggcgaa cgcggagagc acgccatgaa ggcctcgggc 50

 acgctacgag agtacaaggt agtgggtcgc tgcctgccca cccccaaatg 100

 ccacacgccg cccctctacc gcatgcgaat ctttgcgcct aatcatgtcg 150

 tcgccaagtc ccgcttctgg tactttgtat ctcagttaaa gaagatgaag 200

 aagtcttcag gggagattgt ctactgtggg caggtgtttg agaagtcccc 250

 cctgcgggtg aagaacttcg ggatctggct gcgctatgac tcccggagcg 300

 gcacccacaa catgtaccgg gaataccggg acctgaccac cgcaggcgct 350

 gtcacccagt gctaccgaga catgggtgcc cggcaccgcg cccgagccca 400

 ctccattcag atcatgaagg tggaggagat cgcggccagc aagtgccgcc 450

 ggccggctgt caagcagttc cacgactcca agatcaagtt cccgctgccc 500

 caccgggtcc tgcgccgtca gcacaagcca cgcttcacca ccaagaggcc 550

 caacaccttc ttctaggtgc agggccctcg tccgggtgtg ccccaaataa 600

 actcaggaac gccccggt 618

<210> 106
<211> 176
<212> PRT
<213> Homo sapien

<400> 106
 Met Lys Ala Ser Gly Thr Leu Arg Glu Tyr Lys Val Val Gly Arg
   1               5                  10                  15

 Cys Leu Pro Thr Pro Lys Cys His Thr Pro Pro Leu Tyr Arg Met
                  20                  25                  30

 Arg Ile Phe Ala Pro Asn His Val Val Ala Lys Ser Arg Phe Trp
                  35                  40                  45

 Tyr Phe Val Ser Gln Leu Lys Lys Met Lys Lys Ser Ser Gly Glu
                  50                  55                  60

 Ile Val Tyr Cys Gly Gln Val Phe Glu Lys Ser Pro Leu Arg Val
                  65                  70                  75

 Lys Asn Phe Gly Ile Trp Leu Arg Tyr Asp Ser Arg Ser Gly Thr
                  80                  85                  90

 His Asn Met Tyr Arg Glu Tyr Arg Asp Leu Thr Thr Ala Gly Ala
                  95                 100                 105

 Val Thr Gln Cys Tyr Arg Asp Met Gly Ala Arg His Arg Ala Arg
                 110                 115                 120

 Ala His Ser Ile Gln Ile Met Lys Val Glu Glu Ile Ala Ala Ser
                 125                 130                 135

 Lys Cys Arg Arg Pro Ala Val Lys Gln Phe His Asp Ser Lys Ile
                 140                 145                 150

 Lys Phe Pro Leu Pro His Arg Val Leu Arg Arg Gln His Lys Pro
                 155                 160                 165

 Arg Phe Thr Thr Lys Arg Pro Asn Thr Phe Phe
                 170                 175

<210> 107
<211> 2767
<212> DNA
<213> Homo sapien

<400> 107
 gggcgggcgc attgcagact gcggagtcag acggtgctat gtacgccctc 50

 ttcctcctgg ccagcctcct gggcgcggct ctagccggcc cggtccttgg 100

 actgaaagaa tgcaccaggg gctcggcagt gtggtgccag aatgtgaaga 150

 cggcgtccga ctgcggggca gtgaagcact gcctgcagac cgtttggaac 200

 aagccaacag tgaaatccct tccctgcgac atatgcaaag acgttgtcac 250

 cgcagctggt gatatgctga aggacaatgc cactgaggag gagatccttg 300

 tttacttgga gaagacctgt gactggcttc cgaaaccgaa catgtctgct 350

 tcatgcaagg agatagtgga ctcctacctc cctgtcatcc tggacatcat 400

 taaaggagaa atgagccgtc ctggggaggt gtgctctgct ctcaacctct 450

 gcgagtctct ccagaagcac ctagcagagc tgaatcacca gaagcagctg 500

 gagtccaata agatcccaga gctggacatg actgaggtgg tggccccctt 550

 catggccaac atccctctcc tcctctaccc tcaggacggc ccccgcagca 600

 agccccagcc aaaggataat ggggacgttt gccaggactg cattcagatg 650

 gtgactgaca tccagactgc tgtacggacc aactccacct ttgtccaggc 700

 cttggtggaa catgtcaagg aggagtgtga ccgcctgggc cctggcatgg 750

 ccgacatatg caagaactat atcagccagt attctgaaat tgctatccag 800

 atgatgatgc acatgcaacc caaggagatc tgtgcgctgg ttgggttctg 850

 tgatgaggtg aaagagatgc ccatgcagac tctggtcccc gccaaagtgg 900

 cctccaagaa tgtcatccct gccctggaac tggtggagcc cattaagaag 950

 cacgaggtcc cagcaaagtc tgatgtttac tgtgaggtgt gtgaattcct 1000

 ggtgaaggag gtgaccaagc tgattgacaa caacaagact gagaaagaaa 1050

 tactcgacgc ttttgacaaa atgtgctcga agctgccgaa gtccctgtcg 1100

 gaagagtgcc aggaggtggt ggacacgtac ggcagctcca tcctgtccat 1150

 cctgctggag gaggtcagcc ctgagctggt gtgcagcatg ctgcacctct 1200

 gctctggcac gcggctgcct gcactgaccg ttcacgtgac tcagccaaag 1250

 gacggtggct tctgcgaagt gtgcaagaag ctggtgggtt atttggatcg 1300

 caacctggag aaaaacagca ccaagcagga gatcctggct gctcttgaga 1350

 aaggctgcag cttcctgcca gacccttacc agaagcagtg tgatcagttt 1400

 gtggcagagt acgagcccgt gctgatcgag atcctggtgg aggtgatgga 1450

 tccttccttc gtgtgcttga aaattggagc ctgcccctcg gcccataagc 1500

 ccttgttggg aactgagaag tgtatatggg gcccaagcta ctggtgccag 1550

 aacacagaga cagcagccca gtgcaatgct gtcgagcatt gcaaacgcca 1600

 tgtgtggaac taggaggagg aatattccat cttggcagaa accacagcat 1650

 tggttttttt ctacttgtgt gtctggggga atgaacgcac agatctgttt 1700

 gactttgtta taaaaatagg gctcccccac ctcccccatt tctgtgtcct 1750

 ttattgtagc attgctgtct gcaagggagc ccctagcccc tagcccctgg 1800

 cagacatagc tgcttcagtg ccccttttct ctctgctaga tggatgttga 1850

 tgcactggag gtcttttagc ctgcccttgc atggcgcctg ctggaggagg 1900

 agagagctct gctggcatga gccacagttt cttgactgga ggccatcaac 1950

 cctcttggtt gaggccttgt tctgagccct gacatgtgct tgggcactgg 2000

 tgggcctggg cttctgaggt ggcctcctgc cctgatcagg gaccctcccc 2050

 gctttcctgg gcctctcagt tgaacaaagc agcaaaacaa aggcagtttt 2100

 atatgaaaga ttagaagcct ggaataatca ggctttttaa atgatgtaat 2150

 tcccactgta atagcatagg gattttggaa gcagctgctg gtggcttggg 2200

 acatcagtgg ggccaagggt tctctgtccc tggttcaact gtgatttggc 2250

 tttcccgtgt ctttcctggt gatgccttgt ttggggttct gtgggtttgg 2300

 gtgggaagag ggccatctgc ctgaatgtaa cctgctagct ctccgaagcc 2350

 ctgcgggcct ggcttgtgtg agcgtgtgga cagtggtggc cgcgctgtgc 2400

 ctgctcgtgt tgcctacatg tccctggctg ttgaggcgct gcttcagcct 2450

 gcacccctcc cttgtctcat agatgctcct tttgaccttt tcaaataaat 2500

 atggatggcg agctcctagg cctctggctt cctggtagag ggcggcatgc 2550

 cgaagggtct gtctgggtgt ggattggatg ctgggggtgt gggggttgga 2600

 agctgtctgt ggcccacttg ggcacccacg cttctgtcca cttctggttg 2650

 ccaggagaca gcaagcaaag ccagcaggac atgaagttgc tattaaatgg 2700

 acttcgtgat ttttgttttg cactaaagtt tctgtgattt aacaataaaa 2750

 ttctgttagc ccccccg 2767

<210> 108
<211> 524
<212> PRT
<213> Homo sapien

<400> 108
 Met Tyr Ala Leu Phe Leu Leu Ala Ser Leu Leu Gly Ala Ala Leu
   1               5                  10                  15

 Ala Gly Pro Val Leu Gly Leu Lys Glu Cys Thr Arg Gly Ser Ala
                  20                  25                  30

 Val Trp Cys Gln Asn Val Lys Thr Ala Ser Asp Cys Gly Ala Val
                  35                  40                  45

 Lys His Cys Leu Gln Thr Val Trp Asn Lys Pro Thr Val Lys Ser
                  50                  55                  60

 Leu Pro Cys Asp Ile Cys Lys Asp Val Val Thr Ala Ala Gly Asp
                  65                  70                  75

 Met Leu Lys Asp Asn Ala Thr Glu Glu Glu Ile Leu Val Tyr Leu
                  80                  85                  90

 Glu Lys Thr Cys Asp Trp Leu Pro Lys Pro Asn Met Ser Ala Ser
                  95                 100                 105

 Cys Lys Glu Ile Val Asp Ser Tyr Leu Pro Val Ile Leu Asp Ile
                 110                 115                 120

 Ile Lys Gly Glu Met Ser Arg Pro Gly Glu Val Cys Ser Ala Leu
                 125                 130                 135

 Asn Leu Cys Glu Ser Leu Gln Lys His Leu Ala Glu Leu Asn His
                 140                 145                 150

 Gln Lys Gln Leu Glu Ser Asn Lys Ile Pro Glu Leu Asp Met Thr
                 155                 160                 165

 Glu Val Val Ala Pro Phe Met Ala Asn Ile Pro Leu Leu Leu Tyr
                 170                 175                 180

 Pro Gln Asp Gly Pro Arg Ser Lys Pro Gln Pro Lys Asp Asn Gly
                 185                 190                 195

 Asp Val Cys Gln Asp Cys Ile Gln Met Val Thr Asp Ile Gln Thr
                 200                 205                 210

 Ala Val Arg Thr Asn Ser Thr Phe Val Gln Ala Leu Val Glu His
                 215                 220                 225

 Val Lys Glu Glu Cys Asp Arg Leu Gly Pro Gly Met Ala Asp Ile
                 230                 235                 240

 Cys Lys Asn Tyr Ile Ser Gln Tyr Ser Glu Ile Ala Ile Gln Met
                 245                 250                 255

 Met Met His Met Gln Pro Lys Glu Ile Cys Ala Leu Val Gly Phe
                 260                 265                 270

 Cys Asp Glu Val Lys Glu Met Pro Met Gln Thr Leu Val Pro Ala
                 275                 280                 285

 Lys Val Ala Ser Lys Asn Val Ile Pro Ala Leu Glu Leu Val Glu
                 290                 295                 300

 Pro Ile Lys Lys His Glu Val Pro Ala Lys Ser Asp Val Tyr Cys
                 305                 310                 315

 Glu Val Cys Glu Phe Leu Val Lys Glu Val Thr Lys Leu Ile Asp
                 320                 325                 330

 Asn Asn Lys Thr Glu Lys Glu Ile Leu Asp Ala Phe Asp Lys Met
                 335                 340                 345

 Cys Ser Lys Leu Pro Lys Ser Leu Ser Glu Glu Cys Gln Glu Val
                 350                 355                 360

 Val Asp Thr Tyr Gly Ser Ser Ile Leu Ser Ile Leu Leu Glu Glu
                 365                 370                 375

 Val Ser Pro Glu Leu Val Cys Ser Met Leu His Leu Cys Ser Gly
                 380                 385                 390

 Thr Arg Leu Pro Ala Leu Thr Val His Val Thr Gln Pro Lys Asp
                 395                 400                 405

 Gly Gly Phe Cys Glu Val Cys Lys Lys Leu Val Gly Tyr Leu Asp
                 410                 415                 420

 Arg Asn Leu Glu Lys Asn Ser Thr Lys Gln Glu Ile Leu Ala Ala
                 425                 430                 435

 Leu Glu Lys Gly Cys Ser Phe Leu Pro Asp Pro Tyr Gln Lys Gln
                 440                 445                 450

 Cys Asp Gln Phe Val Ala Glu Tyr Glu Pro Val Leu Ile Glu Ile
                 455                 460                 465

 Leu Val Glu Val Met Asp Pro Ser Phe Val Cys Leu Lys Ile Gly
                 470                 475                 480

 Ala Cys Pro Ser Ala His Lys Pro Leu Leu Gly Thr Glu Lys Cys
                 485                 490                 495

 Ile Trp Gly Pro Ser Tyr Trp Cys Gln Asn Thr Glu Thr Ala Ala
                 500                 505                 510

 Gln Cys Asn Ala Val Glu His Cys Lys Arg His Val Trp Asn
                 515                 520

<210> 109
<211> 649
<212> DNA
<213> Homo sapien

<400> 109
 agaatacact cacaagccac tccgctgctc gcctctccgc cccgcgtcca 50

 gctcgcccag ctcgcccagc gtccgccgcg cctcgccaag gcttcaacgg 100

 accacaccaa aatgccatct caaatggaac acgccatgga aaccatgatg 150

 tttacatttc acaaattcgc tggggataaa ggctacttaa caaaggagga 200

 cctgagagta ctcatggaaa aggagttccc tggatttttg gaaaatcaaa 250

 aagaccctct ggctgtggac aaaataatga aggacctgga ccagtgtaga 300

 gatggcaaag tgggcttcca gagcttcttt tccctaattg cgggcctcac 350

 cattgcatgc aatgactatt ttgtagtaca catgaagcag aagggaaaga 400

 agtaggcaga aatgagcagt tcgctcctcc ctgataagag ttgtccaaag 450

 ggtcgcttaa ggaatctgcc ccacagcttc ccccatagaa ggatttcatg 500

 agcagatcag gacacttagc aaatgtaaaa ataaaatcta actctcattt 550

 gacaagcaga gaaagaaaag ttaaatacca gataagcttt tgatttttgt 600

 attgtttgca tccccttgcc ctcaataaat aaagttcttt tttagttcc 649

<210> 110
<211> 97
<212> PRT
<213> Homo sapien

<400> 110
 Met Pro Ser Gln Met Glu His Ala Met Glu Thr Met Met Phe Thr
   1               5                  10                  15

 Phe His Lys Phe Ala Gly Asp Lys Gly Tyr Leu Thr Lys Glu Asp
                  20                  25                  30

 Leu Arg Val Leu Met Glu Lys Glu Phe Pro Gly Phe Leu Glu Asn
                  35                  40                  45

 Gln Lys Asp Pro Leu Ala Val Asp Lys Ile Met Lys Asp Leu Asp
                  50                  55                  60

 Gln Cys Arg Asp Gly Lys Val Gly Phe Gln Ser Phe Phe Ser Leu
                  65                  70                  75

 Ile Ala Gly Leu Thr Ile Ala Cys Asn Asp Tyr Phe Val Val His
                  80                  85                  90

 Met Lys Gln Lys Gly Lys Lys
                  95

<210> 111
<211> 1821
<212> DNA
<213> Homo sapien

<400> 111
 cgcgtgaact gcttcctgca ggctggccat ggcgcttcac gttcccaagg 50

 ctccgggctt tgcccagatg ctcaaggagg gagcgaaaca cttttcagga 100

 ttagaagagg ctgtgtatag aaacatacaa gcttgcaagg agcttgccca 150

 aaccactcgt acagcatatg gaccaaaagg aatgaacaaa atggttatca 200

 accacttgga gaagttgttt gtgacaaacg atgcagcaac tattttaaga 250

 gaactagaag tacagcatcc tgctgcaaaa atgattgtaa tggcttctca 300

 tatgcaagag caagaagttg gagatggcac aaactttgtt ctggtatttg 350

 ctggagctct cctggaatta gctgaagaac ttctgaggat tggcctgtca 400

 gtttcagagg tcatagaagg ttatgaaata gcctgcagaa aagctcatga 450

 gattcttcct aatttggtat gttgttctgc aaaaaacctt cgagatattg 500

 atgaagtctc atctctactt cgtacctcca taatgagtaa acaatatggt 550

 aatgaagtat ttctggccaa gcttattgct caggcatgcg tatctatttt 600

 tcctgattcc ggccatttca atgttgataa catcagagtt tgtaaaattc 650

 tgggctctgg tatcagttcc tcttcagtat tgcatggcat ggtttttaag 700

 aaggaaaccg aaggtgatgt aacatctgtc aaagatgcaa aaatagcagt 750

 gtactcttgt ccttttgatg gcatgataac agaaactaag ggaacagtgt 800

 tgataaagac tgctgaagaa ttgatgaatt ttagtaaggg agaagaaaac 850

 ctcatggatg cacaagtcaa agctattgct gatactggtg caaatgtcgt 900

 agtaacaggt ggcaaagtgg cagacatggc tcttcattat gcaaataaat 950

 ataatatcat gttagtgagg ctaaactcaa aatgggatct ccgaagactt 1000

 tgtaaaactg ttggtgctac agctcttcct agattgacac ctcctgtcct 1050

 tgaagaaatg ggacactgtg acagtgttta cctctcagaa gttggagata 1100

 ctcaggtggt ggtttttaag catgaaaagg aagatggcgc catttctacc 1150

 atagtacttc gaggctctac agacaatctg atggatgaca tagaaagggt 1200

 agtagacgat ggtgttaata ctttcaaagt tcttacaagg gataaacgtc 1250

 ttgtacccgg aggtggagca acagaaattg aattagccaa acagatcaca 1300

 tcatatggag agacatgtcc tggacttgaa cagtatgcta ttaagaagtt 1350

 tgctgaggca tttgaagcta ttccccgcgc actggcagaa aactctggag 1400

 ttaaggccaa tgaagtaatc tctaaacttt atgcagtaca tcaagaagga 1450

 aataaaaacg ttggattaga tattgaggct gaagtccctg ctgtaaagga 1500

 catgctggaa gctggtattc tagatactta cctgggaaaa tattgggcta 1550

 tcaaactcgc tactaatgct gcagtcactg tacttagagt ggatcagatc 1600

 atcatggcaa aaccagctgg tgggcccaag cctccaagtg ggaagaaaga 1650

 ctgggatgat gaccaaaatg attgaaattg gcttaatttt tactgtaggt 1700

 gaaggctgta tttgtagtag tactcaagaa tcacctgatg ttttcttatt 1750

 ctccttaaat taagagttat tttgtgtttg tattcttggc tggatgttat 1800

 aataaacata ttgttactgt c 1821

<210> 112
<211> 548
<212> PRT
<213> Homo sapien

<400> 112
 Met Ala Leu His Val Pro Lys Ala Pro Gly Phe Ala Gln Met Leu
   1               5                  10                  15

 Lys Glu Gly Ala Lys His Phe Ser Gly Leu Glu Glu Ala Val Tyr
                  20                  25                  30

 Arg Asn Ile Gln Ala Cys Lys Glu Leu Ala Gln Thr Thr Arg Thr
                  35                  40                  45

 Ala Tyr Gly Pro Lys Gly Met Asn Lys Met Val Ile Asn His Leu
                  50                  55                  60

 Glu Lys Leu Phe Val Thr Asn Asp Ala Ala Thr Ile Leu Arg Glu
                  65                  70                  75

 Leu Glu Val Gln His Pro Ala Ala Lys Met Ile Val Met Ala Ser
                  80                  85                  90

 His Met Gln Glu Gln Glu Val Gly Asp Gly Thr Asn Phe Val Leu
                  95                 100                 105

 Val Phe Ala Gly Ala Leu Leu Glu Leu Ala Glu Glu Leu Leu Arg
                 110                 115                 120

 Ile Gly Leu Ser Val Ser Glu Val Ile Glu Gly Tyr Glu Ile Ala
                 125                 130                 135

 Cys Arg Lys Ala His Glu Ile Leu Pro Asn Leu Val Cys Cys Ser
                 140                 145                 150

 Ala Lys Asn Leu Arg Asp Ile Asp Glu Val Ser Ser Leu Leu Arg
                 155                 160                 165

 Thr Ser Ile Met Ser Lys Gln Tyr Gly Asn Glu Val Phe Leu Ala
                 170                 175                 180

 Lys Leu Ile Ala Gln Ala Cys Val Ser Ile Phe Pro Asp Ser Gly
                 185                 190                 195

 His Phe Asn Val Asp Asn Ile Arg Val Cys Lys Ile Leu Gly Ser
                 200                 205                 210

 Gly Ile Ser Ser Ser Ser Val Leu His Gly Met Val Phe Lys Lys
                 215                 220                 225

 Glu Thr Glu Gly Asp Val Thr Ser Val Lys Asp Ala Lys Ile Ala
                 230                 235                 240

 Val Tyr Ser Cys Pro Phe Asp Gly Met Ile Thr Glu Thr Lys Gly
                 245                 250                 255

 Thr Val Leu Ile Lys Thr Ala Glu Glu Leu Met Asn Phe Ser Lys
                 260                 265                 270

 Gly Glu Glu Asn Leu Met Asp Ala Gln Val Lys Ala Ile Ala Asp
                 275                 280                 285

 Thr Gly Ala Asn Val Val Val Thr Gly Gly Lys Val Ala Asp Met
                 290                 295                 300

 Ala Leu His Tyr Ala Asn Lys Tyr Asn Ile Met Leu Val Arg Leu
                 305                 310                 315

 Asn Ser Lys Trp Asp Leu Arg Arg Leu Cys Lys Thr Val Gly Ala
                 320                 325                 330

 Thr Ala Leu Pro Arg Leu Thr Pro Pro Val Leu Glu Glu Met Gly
                 335                 340                 345

 His Cys Asp Ser Val Tyr Leu Ser Glu Val Gly Asp Thr Gln Val
                 350                 355                 360

 Val Val Phe Lys His Glu Lys Glu Asp Gly Ala Ile Ser Thr Ile
                 365                 370                 375

 Val Leu Arg Gly Ser Thr Asp Asn Leu Met Asp Asp Ile Glu Arg
                 380                 385                 390

 Val Val Asp Asp Gly Val Asn Thr Phe Lys Val Leu Thr Arg Asp
                 395                 400                 405

 Lys Arg Leu Val Pro Gly Gly Gly Ala Thr Glu Ile Glu Leu Ala
                 410                 415                 420

 Lys Gln Ile Thr Ser Tyr Gly Glu Thr Cys Pro Gly Leu Glu Gln
                 425                 430                 435

 Tyr Ala Ile Lys Lys Phe Ala Glu Ala Phe Glu Ala Ile Pro Arg
                 440                 445                 450

 Ala Leu Ala Glu Asn Ser Gly Val Lys Ala Asn Glu Val Ile Ser
                 455                 460                 465

 Lys Leu Tyr Ala Val His Gln Glu Gly Asn Lys Asn Val Gly Leu
                 470                 475                 480

 Asp Ile Glu Ala Glu Val Pro Ala Val Lys Asp Met Leu Glu Ala
                 485                 490                 495

 Gly Ile Leu Asp Thr Tyr Leu Gly Lys Tyr Trp Ala Ile Lys Leu
                 500                 505                 510

 Ala Thr Asn Ala Ala Val Thr Val Leu Arg Val Asp Gln Ile Ile
                 515                 520                 525

 Met Ala Lys Pro Ala Gly Gly Pro Lys Pro Pro Ser Gly Lys Lys
                 530                 535                 540

 Asp Trp Asp Asp Asp Gln Asn Asp
                 545

<210> 113
<211> 1973
<212> DNA
<213> Homo sapien

<400> 113
 ggatccggca acgaaggtac catggcggga cgtggcgcca tggtgctgtt 50

 gcacgtgctg tttgagcacg cggtcggcta cgcgctcgtg gcgctgaagg 100

 aagtggagga gatcagtctg ctgcagccgc aggtggagga gtccgtgctc 150

 aacctgggca aattccacag catcgttcgt ctggtggcct tttgtccctt 200

 tgcctcatcc caggttgcct tggaaaatgc caacgccgtg tctgaagggg 250

 ttgttcatga ggacctccgc ctgctcttgg agacccacct gccgtccaaa 300

 aagaagaaag tactcttggg agttggggat cccaagattg gtgccgcaat 350

 acaggaggag ttagggtaca actgccagac tggaggagtc atagctgaga 400

 tcctgcgagg agttcgtctg cacttccaca atctggtgaa gggtctgacc 450

 gatctgtcag cttgtaaagc acagctgggg ctgggacaca gctattcccg 500

 tgccaaagtt aagtttaatg tgaaccgggt ggacaatatg atcatccagt 550

 ccattagcct cctggaccag ctggataagg acatcaatac cttctctatg 600

 cgtgtcaggg agtggtacgg gtatcacttt ccggagctgg tgaagatcat 650

 caacgacaat gccacatact gccgtcttgc ccagtttatt ggaaaccgaa 700

 gggaactgaa tgaggacaag ctggagaagc tggaggagct gacaatggat 750

 ggggccaagg ctaaggctat tctggatgcc tcacggtcct ccatgggcat 800

 ggacatatct gccattgact tgataaacat cgagagcttc tccagtcgtg 850

 tggtgtcttt atctgaatac cgccagagcc tacacactta cctgcgctcc 900

 aagatgagcc aagtagcccc cagcctgtca gccctaattg gggaagcggt 950

 aggtgcacgt ctcatcgcac atgctggcag cctcaccaac ctggccaagt 1000

 atccagcatc cacagtgcag atccttgggg ctgaaaaggc cctgttcaga 1050

 gccctgaaga caaggggtaa cactccaaaa tatggactca ttttccactc 1100

 caccttcatt ggccgagcag ctgccaagaa caaaggccgc atctcccgat 1150

 acctggcaaa caaatgcagt attgcctcac gaatcgattg cttctctgag 1200

 gtgcccacga gtgtattcgg ggagaagctt cgagaacaag ttgaagagcg 1250

 actgtccttc tatgagactg gagagatacc acgaaagaat ctggatgtca 1300

 tgaaggaagc aatggttcag gcagaggcag aggaagcggc tgctgagatt 1350

 actaggaagc tggagaaaca ggagaagaaa cgcttaaaga aggaaaagaa 1400

 acggctggct gcacttgccc tcgcgtcttc agaaaacagc agtagtactc 1450

 cagaggagtg tgaggagacg agtgaaaaac ccaaaaagaa gaaaaagcaa 1500

 aagccccagg aggttcctca ggagaatgga atggaagacc catctatctc 1550

 tttctccaaa cccaagaaaa agaaatcttt ttccaaggag gagttgatga 1600

 gtagcgatct tgaagagacc gctggcagca ccagtattcc caagaggaag 1650

 aagtctacac ccaaggagga aacagttaat gaccctgagg aggcaggcca 1700

 cagaagtcgg tccaagaaaa agaggaaatt ctccaaagag gagccggtca 1750

 gcagtgggcc tgaagaggcg gttggcaaga gcagctccaa gaagaagaaa 1800

 aagttccata aagcatccca ggaagattag aatgcaaatg gacattctct 1850

 gggaggtggg gcataccata gcccaaggtg acatttccca ccctgtgccc 1900

 gtgttcccaa taaaaacaaa ttcacaagaa aaaaaaaaaa aaaaaaaaaa 1950

 ttcctgaggc cgcaagggaa ttc 1973

<210> 114
<211> 602
<212> PRT
<213> Homo sapien

<400> 114
 Met Ala Gly Arg Gly Ala Met Val Leu Leu His Val Leu Phe Glu
   1               5                  10                  15

 His Ala Val Gly Tyr Ala Leu Val Ala Leu Lys Glu Val Glu Glu
                  20                  25                  30

 Ile Ser Leu Leu Gln Pro Gln Val Glu Glu Ser Val Leu Asn Leu
                  35                  40                  45

 Gly Lys Phe His Ser Ile Val Arg Leu Val Ala Phe Cys Pro Phe
                  50                  55                  60

 Ala Ser Ser Gln Val Ala Leu Glu Asn Ala Asn Ala Val Ser Glu
                  65                  70                  75

 Gly Val Val His Glu Asp Leu Arg Leu Leu Leu Glu Thr His Leu
                  80                  85                  90

 Pro Ser Lys Lys Lys Lys Val Leu Leu Gly Val Gly Asp Pro Lys
                  95                 100                 105

 Ile Gly Ala Ala Ile Gln Glu Glu Leu Gly Tyr Asn Cys Gln Thr
                 110                 115                 120

 Gly Gly Val Ile Ala Glu Ile Leu Arg Gly Val Arg Leu His Phe
                 125                 130                 135

 His Asn Leu Val Lys Gly Leu Thr Asp Leu Ser Ala Cys Lys Ala
                 140                 145                 150

 Gln Leu Gly Leu Gly His Ser Tyr Ser Arg Ala Lys Val Lys Phe
                 155                 160                 165

 Asn Val Asn Arg Val Asp Asn Met Ile Ile Gln Ser Ile Ser Leu
                 170                 175                 180

 Leu Asp Gln Leu Asp Lys Asp Ile Asn Thr Phe Ser Met Arg Val
                 185                 190                 195

 Arg Glu Trp Tyr Gly Tyr His Phe Pro Glu Leu Val Lys Ile Ile
                 200                 205                 210

 Asn Asp Asn Ala Thr Tyr Cys Arg Leu Ala Gln Phe Ile Gly Asn
                 215                 220                 225

 Arg Arg Glu Leu Asn Glu Asp Lys Leu Glu Lys Leu Glu Glu Leu
                 230                 235                 240

 Thr Met Asp Gly Ala Lys Ala Lys Ala Ile Leu Asp Ala Ser Arg
                 245                 250                 255

 Ser Ser Met Gly Met Asp Ile Ser Ala Ile Asp Leu Ile Asn Ile
                 260                 265                 270

 Glu Ser Phe Ser Ser Arg Val Val Ser Leu Ser Glu Tyr Arg Gln
                 275                 280                 285

 Ser Leu His Thr Tyr Leu Arg Ser Lys Met Ser Gln Val Ala Pro
                 290                 295                 300

 Ser Leu Ser Ala Leu Ile Gly Glu Ala Val Gly Ala Arg Leu Ile
                 305                 310                 315

 Ala His Ala Gly Ser Leu Thr Asn Leu Ala Lys Tyr Pro Ala Ser
                 320                 325                 330

 Thr Val Gln Ile Leu Gly Ala Glu Lys Ala Leu Phe Arg Ala Leu
                 335                 340                 345

 Lys Thr Arg Gly Asn Thr Pro Lys Tyr Gly Leu Ile Phe His Ser
                 350                 355                 360

 Thr Phe Ile Gly Arg Ala Ala Ala Lys Asn Lys Gly Arg Ile Ser
                 365                 370                 375

 Arg Tyr Leu Ala Asn Lys Cys Ser Ile Ala Ser Arg Ile Asp Cys
                 380                 385                 390

 Phe Ser Glu Val Pro Thr Ser Val Phe Gly Glu Lys Leu Arg Glu
                 395                 400                 405

 Gln Val Glu Glu Arg Leu Ser Phe Tyr Glu Thr Gly Glu Ile Pro
                 410                 415                 420

 Arg Lys Asn Leu Asp Val Met Lys Glu Ala Met Val Gln Ala Glu
                 425                 430                 435

 Ala Glu Glu Ala Ala Ala Glu Ile Thr Arg Lys Leu Glu Lys Gln
                 440                 445                 450

 Glu Lys Lys Arg Leu Lys Lys Glu Lys Lys Arg Leu Ala Ala Leu
                 455                 460                 465

 Ala Leu Ala Ser Ser Glu Asn Ser Ser Ser Thr Pro Glu Glu Cys
                 470                 475                 480

 Glu Glu Thr Ser Glu Lys Pro Lys Lys Lys Lys Lys Gln Lys Pro
                 485                 490                 495

 Gln Glu Val Pro Gln Glu Asn Gly Met Glu Asp Pro Ser Ile Ser
                 500                 505                 510

 Phe Ser Lys Pro Lys Lys Lys Lys Ser Phe Ser Lys Glu Glu Leu
                 515                 520                 525

 Met Ser Ser Asp Leu Glu Glu Thr Ala Gly Ser Thr Ser Ile Pro
                 530                 535                 540

 Lys Arg Lys Lys Ser Thr Pro Lys Glu Glu Thr Val Asn Asp Pro
                 545                 550                 555

 Glu Glu Ala Gly His Arg Ser Arg Ser Lys Lys Lys Arg Lys Phe
                 560                 565                 570

 Ser Lys Glu Glu Pro Val Ser Ser Gly Pro Glu Glu Ala Val Gly
                 575                 580                 585

 Lys Ser Ser Ser Lys Lys Lys Lys Lys Phe His Lys Ala Ser Gln
                 590                 595                 600

 Glu Asp


<210> 115
<211> 1883
<212> DNA
<213> Homo sapien

<400> 115
 atgcccgaga atgtggcacc ccggagcggg gcgactgccg gggctgccgg 50

 cggccgcggg aaaggcgcct atcaggaccg cgacaagcca gcccagatcc 100

 gcttcagcaa catttccgcc gccaaagcgg ttgctgatgc tattagaaca 150

 agccttggac caaaaggaat ggataaaatg attcaagatg gaaaaggtga 200

 tgtaaccatt acaaatgatg gtgctaccat tctgaaacaa atgcaagtat 250

 tacatccagc agccagaatg ctggtggagc tgtctaaggc tcaagatata 300

 gaagcaggag atggcaccac atcagtagtc atcattgctg gctccctctt 350

 agattcttgt accaagcttc ttcagaaagg gattcatcca accatcattt 400

 ctgagtcatt ccagaaggcc ctggaaaagg gcattgaaat cttgactgac 450

 atgtctcgac ctgtggaact gagtgacaga gaaactttgt taaatagtgc 500

 aaccacttca ctgaactcaa aggtggtttc tcagtattca agtctgcttt 550

 ctccaatgag tgtaaatgca gtgatgaaag tgattgaccc agccacagcc 600

 accagtgtag atcttagaga tattaaaata gttaagaagc ttggtgggac 650

 aattgatgac tgtgagttgg tggaagggct ggttctcacc caaaaagtgt 700

 caaattctgg cataaccaga gttgaaaagg ccaagattgg gcttattcag 750

 ttttgcttat ctgctcccaa aacagacatg gataatcaaa tagtggtttc 800

 tgactatgcc cagatggacc gagtgctgcg agaagagaga gcctatattt 850

 taaatttagt gaagcaaatt aaaaaaacag gatgtaatgt ccttctcata 900

 cagaaatcta ttctaagaga tgctcttagt gatcttgcat tacactttct 950

 gaataaaatg aagatcatgg tgattaagga tattgaaaga gaagacattg 1000

 aattcatttg taagacaatt ggaaccaagc cagttgctca tattgaccaa 1050

 tttactgctg acatgctggg ttctgctgag ttagctgagg aggtcaattt 1100

 aaatggttct ggcaaactgc tcaagattac aggctgtgcc agccctggaa 1150

 aaacagttac aattgttgtt cgtggttcta acaaactggt gattgaagaa 1200

 gctgagcgct ccattcatga tgccctatgt gttattcgtt gtttagtgaa 1250

 gaagagggct cttattgcag gaggtggtgc tccagaaata gagttggccc 1300

 tagcattaac tgaatattca cgaacactga gtggtatgga atcctactgc 1350

 gttcgtgctt ttgcagatgc tatggaggtc attccatcta cactagctga 1400

 aaatgccggc ctgaatccca tttctacagt aacagaacta agaaaccggc 1450

 atgcccaggg agaaaaaact gcaggcatta atgtccgaaa gggtggtatt 1500

 tccaacattt tggaggaact ggttgtccag cctctgttgg tatcagtcag 1550

 tgctctgact cttgcaactg aaactgttcg gagcattctg aaaatagatg 1600

 atgtggtaaa cactcgataa tctggataac tgactagcac cattatgatc 1650

 accagtattg tggctggaat ggaagaagat caccttggtg ttccttgttt 1700

 ggaagattat ttcctctgaa tttctgggct tggtcttcca gttggcattt 1750

 gcctgaagtt gtattgaaac aatttaatga aaatattaaa tatttggttt 1800

 caaaaggcag atttatcttc tcccaacatt ctgttatttc tgatactttt 1850

 gaaaaactaa taaaaactaa taaaagaagc gta 1883

<210> 116
<211> 539
<212> PRT
<213> Homo sapien

<400> 116
 Met Pro Glu Asn Val Ala Pro Arg Ser Gly Ala Thr Ala Gly Ala
   1               5                  10                  15

 Ala Gly Gly Arg Gly Lys Gly Ala Tyr Gln Asp Arg Asp Lys Pro
                  20                  25                  30

 Ala Gln Ile Arg Phe Ser Asn Ile Ser Ala Ala Lys Ala Val Ala
                  35                  40                  45

 Asp Ala Ile Arg Thr Ser Leu Gly Pro Lys Gly Met Asp Lys Met
                  50                  55                  60

 Ile Gln Asp Gly Lys Gly Asp Val Thr Ile Thr Asn Asp Gly Ala
                  65                  70                  75

 Thr Ile Leu Lys Gln Met Gln Val Leu His Pro Ala Ala Arg Met
                  80                  85                  90

 Leu Val Glu Leu Ser Lys Ala Gln Asp Ile Glu Ala Gly Asp Gly
                  95                 100                 105

 Thr Thr Ser Val Val Ile Ile Ala Gly Ser Leu Leu Asp Ser Cys
                 110                 115                 120

 Thr Lys Leu Leu Gln Lys Gly Ile His Pro Thr Ile Ile Ser Glu
                 125                 130                 135

 Ser Phe Gln Lys Ala Leu Glu Lys Gly Ile Glu Ile Leu Thr Asp
                 140                 145                 150

 Met Ser Arg Pro Val Glu Leu Ser Asp Arg Glu Thr Leu Leu Asn
                 155                 160                 165

 Ser Ala Thr Thr Ser Leu Asn Ser Lys Val Val Ser Gln Tyr Ser
                 170                 175                 180

 Ser Leu Leu Ser Pro Met Ser Val Asn Ala Val Met Lys Val Ile
                 185                 190                 195

 Asp Pro Ala Thr Ala Thr Ser Val Asp Leu Arg Asp Ile Lys Ile
                 200                 205                 210

 Val Lys Lys Leu Gly Gly Thr Ile Asp Asp Cys Glu Leu Val Glu
                 215                 220                 225

 Gly Leu Val Leu Thr Gln Lys Val Ser Asn Ser Gly Ile Thr Arg
                 230                 235                 240

 Val Glu Lys Ala Lys Ile Gly Leu Ile Gln Phe Cys Leu Ser Ala
                 245                 250                 255

 Pro Lys Thr Asp Met Asp Asn Gln Ile Val Val Ser Asp Tyr Ala
                 260                 265                 270

 Gln Met Asp Arg Val Leu Arg Glu Glu Arg Ala Tyr Ile Leu Asn
                 275                 280                 285

 Leu Val Lys Gln Ile Lys Lys Thr Gly Cys Asn Val Leu Leu Ile
                 290                 295                 300

 Gln Lys Ser Ile Leu Arg Asp Ala Leu Ser Asp Leu Ala Leu His
                 305                 310                 315

 Phe Leu Asn Lys Met Lys Ile Met Val Ile Lys Asp Ile Glu Arg
                 320                 325                 330

 Glu Asp Ile Glu Phe Ile Cys Lys Thr Ile Gly Thr Lys Pro Val
                 335                 340                 345

 Ala His Ile Asp Gln Phe Thr Ala Asp Met Leu Gly Ser Ala Glu
                 350                 355                 360

 Leu Ala Glu Glu Val Asn Leu Asn Gly Ser Gly Lys Leu Leu Lys
                 365                 370                 375

 Ile Thr Gly Cys Ala Ser Pro Gly Lys Thr Val Thr Ile Val Val
                 380                 385                 390

 Arg Gly Ser Asn Lys Leu Val Ile Glu Glu Ala Glu Arg Ser Ile
                 395                 400                 405

 His Asp Ala Leu Cys Val Ile Arg Cys Leu Val Lys Lys Arg Ala
                 410                 415                 420

 Leu Ile Ala Gly Gly Gly Ala Pro Glu Ile Glu Leu Ala Leu Ala
                 425                 430                 435

 Leu Thr Glu Tyr Ser Arg Thr Leu Ser Gly Met Glu Ser Tyr Cys
                 440                 445                 450

 Val Arg Ala Phe Ala Asp Ala Met Glu Val Ile Pro Ser Thr Leu
                 455                 460                 465

 Ala Glu Asn Ala Gly Leu Asn Pro Ile Ser Thr Val Thr Glu Leu
                 470                 475                 480

 Arg Asn Arg His Ala Gln Gly Glu Lys Thr Ala Gly Ile Asn Val
                 485                 490                 495

 Arg Lys Gly Gly Ile Ser Asn Ile Leu Glu Glu Leu Val Val Gln
                 500                 505                 510

 Pro Leu Leu Val Ser Val Ser Ala Leu Thr Leu Ala Thr Glu Thr
                 515                 520                 525

 Val Arg Ser Ile Leu Lys Ile Asp Asp Val Val Asn Thr Arg
                 530                 535

<210> 117
<211> 975
<212> DNA
<213> Homo sapien

<400> 117
 gggggggaag tgctctaact tttcttaagg ttttgttgct agcccttcaa 50

 gtgcactgag ctatgtgact cggatggtct ttcacacggc acatttggac 100

 atttccagaa ctaccatgag atggtttaga cgggaattca tgcaaatgag 150

 gggtcaaaaa tggtatagtg accccgtcca cgtcctccaa gctcacgacc 200

 ttggagcccc gtggagctgg actgaggagg aggctgcaca gcgggagagc 250

 agctggtcca gaccagccct gcagccccca ctcagccggc agccagatgg 300

 ccccgcaagg cctccaggga tggcccctag ccacaggccc tggctgaggt 350

 ctctgggtcg gtcagtgaca tgtaggtagg aagcactgaa aatagtgttc 400

 ccagagcact ttgcaactcc ctgggtaaga gggacgacac ctctggtttt 450

 tcaataccaa ttacatggaa cttttctgta atgggtacaa tgaagaagtt 500

 tctaaaaaca cacacaaagc acattgggcc aactatttag taagcccgga 550

 tagacttatt gccaaaaaca aaaaatagct ttcaaaagaa atttaagttc 600

 tatgagaaat tccttagtca tggtgttgcg taaatcatat tttagctgca 650

 cggcattacc ccacacaggg tggcagaact tgaagggtta ctgacgtgta 700

 aatgctggta tttgatttcc tgtgtgtgtt gccctggcat taagggcatt 750

 ttacccttgc agttttacta aaacactgaa aaatattcca agcttcatat 800

 taaccctacc tgtcaacgta acgatttcat gaacgttatt atattgtcga 850

 attcctactg acaacattat aactgtatgg gagcttaact ttataaggaa 900

 atgtattttg acactggtat cttattaaag tattctgatc ctaccaaaaa 950

 aaaaaaaaaa aaaaaaaaaa aaaaa 975

<210> 118
<211> 101
<212> PRT
<213> Homo sapien

<400> 118
 Met Val Phe His Thr Ala His Leu Asp Ile Ser Arg Thr Thr Met
   1               5                  10                  15

 Arg Trp Phe Arg Arg Glu Phe Met Gln Met Arg Gly Gln Lys Trp
                  20                  25                  30

 Tyr Ser Asp Pro Val His Val Leu Gln Ala His Asp Leu Gly Ala
                  35                  40                  45

 Pro Trp Ser Trp Thr Glu Glu Glu Ala Ala Gln Arg Glu Ser Ser
                  50                  55                  60

 Trp Ser Arg Pro Ala Leu Gln Pro Pro Leu Ser Arg Gln Pro Asp
                  65                  70                  75

 Gly Pro Ala Arg Pro Pro Gly Met Ala Pro Ser His Arg Pro Trp
                  80                  85                  90

 Leu Arg Ser Leu Gly Arg Ser Val Thr Cys Arg
                  95                 100

<210> 119
<211> 2518
<212> DNA
<213> Homo sapien

<400> 119
 ctgcggcgcg ccgggcggaa ctttctagaa cgctcggtga gaggcggagg 50

 agcggtaact accccggctg cgcacagctc ggcgctcctt cccgctccct 100

 cacacaccgg cctcagcccg caccggcagt agaagatggt gaaagaaaca 150

 acttactacg atgttttggg ggtcaaaccc aatgctactc aggaagaatt 200

 gaaaaaggct tataggaaac tggctttgaa gtaccatcct gataagaacc 250

 caaatgaagg agagaagttt aaacagattt ctcaagctta cgaagttctc 300

 tctgatgcaa agaaaaggga attatatgac aaaggaggag aacaggcaat 350

 taaagagggt ggagcaggtg gcggttttgg ctcccccatg gacatctttg 400

 atatgttttt tggaggagga ggaaggatgc agagagaaag gagaggtaaa 450

 aatgttgtac atcagctctc agtaacccta gaagacttat ataatggtgc 500

 aacaagaaaa ctggctctgc aaaagaatgt gatttgtgac aaatgtgaag 550

 gtagaggagg taagaaagga gcagtagagt gctgtcccaa ttgccgaggt 600

 actggaatgc aaataagaat tcatcagata ggacctggaa tggttcagca 650

 aattcagtct gtgtgcatgg agtgccaggg ccatggggag cggatcagtc 700

 ctaaagatag atgtaaaagc tgcaacggaa ggaagatagt tcgagagaag 750

 aaaattttag aagttcatat tgacaaaggc atgaaagatg gccagaagat 800

 aacattccat ggtgaaggag accaagaacc aggactggag ccaggcgata 850

 ttatcattgt gttagatcag aaggaccatg ctgtttttac tcgacgagga 900

 gaagaccttt tcatgtgtat ggacatacag ctcgttgaag cactgtgtgg 950

 cttccagaag ccaatatcta ctcttgacaa ccgaaccatc gtcatcacct 1000

 ctcatccagg tcagattgtc aagcatggag atatcaagtg tgtactaaat 1050

 gaaggcatgc caatttatcg tagaccatat gaaaagggtc gcctaatcat 1100

 cgaatttaag gtaaactttc ctgagaatgg ctttctctct cctgataaac 1150

 tgtctttgct ggaaaaactc ctacccgaga ggaaggaagt ggaagagact 1200

 gatgagatgg accaagtaga actggtggac tttgatccaa atcaggaaag 1250

 acggcgccac tacaatggag aagcatatga ggatgatgaa catcatccca 1300

 gaggtggtgt tcagtgtcag acctcttaat gggccagtga ataacactca 1350

 ctgctggcat ttaatgtgca gtagtgaatg agtgaaggac tgtaatcata 1400

 atatgctcac tacttgctct tgtttttgtt ttaataaact atagtagtgt 1450

 tttaaaaagt taaatgaaga ataaacgcaa atataaaagc tctgattttg 1500

 ccctgtatgt atgatgactt cagtgtgcaa gatgaagttt aatacctgta 1550

 aaaactacaa agaagttccc ctagcatttc taggccaaac cttgtaattg 1600

 acttcagcta tgtacgtgga caagcttaga ctgaaatgct aggtatatgt 1650

 attggcttca gtgtatgacc cttcattgtt aagctatgaa agtaaaactc 1700

 tgtatttaac tggcaatgag gaaaaaaaaa ttttgtagag aagtgttggt 1750

 ctgtatagtt ctttatatta agtgggattc attgtaatgc ctctgcattt 1800

 attctgttgc ctcagctgtt acttgaagat ggcgtaatat ataatttatc 1850

 ctgtggtatc agtgataaaa atgatacctt tctgtaggag gggtttatca 1900

 taatatgctg cttcttgaag gcttgcactt ccagaattgt gtttccttct 1950

 gctgtgccat tcatatatat atacatatat atatataatc ttgaccagtc 2000

 ctggtcattt gctcccctcc ttgtctgtgg accatgataa gcccaagtag 2050

 tgacttcaga gctgggtaac agaaattaaa gtgaaaagac ctttacgtgg 2100

 agaatttgca tgcgtaatat aggaaggtgt tctttaggta tgttacagga 2150

 ttactttaaa ccatttgact ttcgctccaa agttatgttg gtagtatagc 2200

 aaattatgat gaatagcttt aattgtatgt ttaaaagtct catatgttca 2250

 catgcttaaa tctgggtatc agaatttaag caattcttga aatgtattgt 2300

 ctccttaata tactaattac aaagcatctc caatgtgtgt cactacaggc 2350

 ttttttttcc cagatcatca aattttggct tttaactaag atacatagct 2400

 ttattttagc tagtctgaat gagtgataca aaaatactat tgaactatag 2450

 ttaaataata ttaaatagga tggagagtaa aagtggagga ctgggtaatg 2500

 agccaagaag aaggggtg 2518

<210> 120
<211> 397
<212> PRT
<213> Homo sapien

<400> 120
 Met Val Lys Glu Thr Thr Tyr Tyr Asp Val Leu Gly Val Lys Pro
   1               5                  10                  15

 Asn Ala Thr Gln Glu Glu Leu Lys Lys Ala Tyr Arg Lys Leu Ala
                  20                  25                  30

 Leu Lys Tyr His Pro Asp Lys Asn Pro Asn Glu Gly Glu Lys Phe
                  35                  40                  45

 Lys Gln Ile Ser Gln Ala Tyr Glu Val Leu Ser Asp Ala Lys Lys
                  50                  55                  60

 Arg Glu Leu Tyr Asp Lys Gly Gly Glu Gln Ala Ile Lys Glu Gly
                  65                  70                  75

 Gly Ala Gly Gly Gly Phe Gly Ser Pro Met Asp Ile Phe Asp Met
                  80                  85                  90

 Phe Phe Gly Gly Gly Gly Arg Met Gln Arg Glu Arg Arg Gly Lys
                  95                 100                 105

 Asn Val Val His Gln Leu Ser Val Thr Leu Glu Asp Leu Tyr Asn
                 110                 115                 120

 Gly Ala Thr Arg Lys Leu Ala Leu Gln Lys Asn Val Ile Cys Asp
                 125                 130                 135

 Lys Cys Glu Gly Arg Gly Gly Lys Lys Gly Ala Val Glu Cys Cys
                 140                 145                 150

 Pro Asn Cys Arg Gly Thr Gly Met Gln Ile Arg Ile His Gln Ile
                 155                 160                 165

 Gly Pro Gly Met Val Gln Gln Ile Gln Ser Val Cys Met Glu Cys
                 170                 175                 180

 Gln Gly His Gly Glu Arg Ile Ser Pro Lys Asp Arg Cys Lys Ser
                 185                 190                 195

 Cys Asn Gly Arg Lys Ile Val Arg Glu Lys Lys Ile Leu Glu Val
                 200                 205                 210

 His Ile Asp Lys Gly Met Lys Asp Gly Gln Lys Ile Thr Phe His
                 215                 220                 225

 Gly Glu Gly Asp Gln Glu Pro Gly Leu Glu Pro Gly Asp Ile Ile
                 230                 235                 240

 Ile Val Leu Asp Gln Lys Asp His Ala Val Phe Thr Arg Arg Gly
                 245                 250                 255

 Glu Asp Leu Phe Met Cys Met Asp Ile Gln Leu Val Glu Ala Leu
                 260                 265                 270

 Cys Gly Phe Gln Lys Pro Ile Ser Thr Leu Asp Asn Arg Thr Ile
                 275                 280                 285

 Val Ile Thr Ser His Pro Gly Gln Ile Val Lys His Gly Asp Ile
                 290                 295                 300

 Lys Cys Val Leu Asn Glu Gly Met Pro Ile Tyr Arg Arg Pro Tyr
                 305                 310                 315

 Glu Lys Gly Arg Leu Ile Ile Glu Phe Lys Val Asn Phe Pro Glu
                 320                 325                 330

 Asn Gly Phe Leu Ser Pro Asp Lys Leu Ser Leu Leu Glu Lys Leu
                 335                 340                 345

 Leu Pro Glu Arg Lys Glu Val Glu Glu Thr Asp Glu Met Asp Gln
                 350                 355                 360

 Val Glu Leu Val Asp Phe Asp Pro Asn Gln Glu Arg Arg Arg His
                 365                 370                 375

 Tyr Asn Gly Glu Ala Tyr Glu Asp Asp Glu His His Pro Arg Gly
                 380                 385                 390

 Gly Val Gln Cys Gln Thr Ser
                 395

<210> 121
<211> 1438
<212> DNA
<213> Homo sapien

<400> 121
 cggtaactac cccggctgcg cacagctcgg cgctccttcc cgctccctca 50

 cacaccgcct cagcccgcac cggcagtaga agatggtgaa agaaacaact 100

 tactacgatg ttttgggggt caaacccaat gctactcagg aagaattgaa 150

 aaaggcttat aggaaactgg ccttgaagta ccatcctgat aagaacccaa 200

 atgaaggaga gaagtttaaa cagatttctc aagcttacga agttctctct 250

 gatgcaaaga aaagggaatt atatgacaaa ggaggagaac aggcaattaa 300

 agagggtgga gcaggtggcg gttttggctc ccccatggac atctttgata 350

 tgttttttgg aggaggagga aggatgcaga gagaaaggag aggtaaaaat 400

 gttgtacatc agctctcagt aaccctagaa gacttatata atggtgcaac 450

 aagaaaactg gctctgcaaa agaatgtgat ttgtgacaaa tgtgaaggta 500

 gaggaggtaa gaaaggagca gtagagtgct gtcccaattg ccgaggtact 550

 ggaatgcaaa taagaattca tcagatagga cctggaatgg ttcagcaaat 600

 tcagtctgtg tgcatggagt gccagggcca tggggagcgg atcagtccta 650

 aagatagatg taaaagctgc aacggaagga agatagttcg agagaagaaa 700

 attttagaag ttcatattga caaaggcatg aaagatggcc agaagataac 750

 attccatggt gaaggagacc aagaaccagg actggagcca ggcgatatta 800

 tcattgtgtt agatcagaag gaccatgctg tttttactcg acgaggagaa 850

 gaccttttca tgtgtatgga catacagctc gttgaagcac tgtgtggctt 900

 ccagaagcca atatctactc ttgacaaccg aaccatcgtc atcacctctc 950

 atccaggtca gattgtcaag catggagata tcaagtgtgt actaaatgaa 1000

 ggcatgccaa tttatcgtag accatatgaa aagggtcgcc taatcatcga 1050

 atttaaggta aactttcctg agaatggctt tctctctcct gataaactgt 1100

 ctttgctgga aaaactccta cccgagagga aggaagtgga agagactgat 1150

 gagatggacc aagtagaact ggtggacttt gatccaaatc aggaaagacg 1200

 gcgccactac aatggagaag catatgagga tgatgaacat catcccagag 1250

 gtggtgttca gtgtcagacc tcttaatggc cagtgaataa cactcactgc 1300

 tggcatttaa tgtgcagtag tgaatgagtg aaggactgta atcataatat 1350

 gctcactact tgctcttgtt tttgttttaa taaactatag tagtgttata 1400

 aaaagttaaa tgaagaataa acgcaaatat aaaagctc 1438

<210> 122
<211> 397
<212> PRT
<213> Homo sapien

<400> 122
 Met Val Lys Glu Thr Thr Tyr Tyr Asp Val Leu Gly Val Lys Pro
   1               5                  10                  15

 Asn Ala Thr Gln Glu Glu Leu Lys Lys Ala Tyr Arg Lys Leu Ala
                  20                  25                  30

 Leu Lys Tyr His Pro Asp Lys Asn Pro Asn Glu Gly Glu Lys Phe
                  35                  40                  45

 Lys Gln Ile Ser Gln Ala Tyr Glu Val Leu Ser Asp Ala Lys Lys
                  50                  55                  60

 Arg Glu Leu Tyr Asp Lys Gly Gly Glu Gln Ala Ile Lys Glu Gly
                  65                  70                  75

 Gly Ala Gly Gly Gly Phe Gly Ser Pro Met Asp Ile Phe Asp Met
                  80                  85                  90

 Phe Phe Gly Gly Gly Gly Arg Met Gln Arg Glu Arg Arg Gly Lys
                  95                 100                 105

 Asn Val Val His Gln Leu Ser Val Thr Leu Glu Asp Leu Tyr Asn
                 110                 115                 120

 Gly Ala Thr Arg Lys Leu Ala Leu Gln Lys Asn Val Ile Cys Asp
                 125                 130                 135

 Lys Cys Glu Gly Arg Gly Gly Lys Lys Gly Ala Val Glu Cys Cys
                 140                 145                 150

 Pro Asn Cys Arg Gly Thr Gly Met Gln Ile Arg Ile His Gln Ile
                 155                 160                 165

 Gly Pro Gly Met Val Gln Gln Ile Gln Ser Val Cys Met Glu Cys
                 170                 175                 180

 Gln Gly His Gly Glu Arg Ile Ser Pro Lys Asp Arg Cys Lys Ser
                 185                 190                 195

 Cys Asn Gly Arg Lys Ile Val Arg Glu Lys Lys Ile Leu Glu Val
                 200                 205                 210

 His Ile Asp Lys Gly Met Lys Asp Gly Gln Lys Ile Thr Phe His
                 215                 220                 225

 Gly Glu Gly Asp Gln Glu Pro Gly Leu Glu Pro Gly Asp Ile Ile
                 230                 235                 240

 Ile Val Leu Asp Gln Lys Asp His Ala Val Phe Thr Arg Arg Gly
                 245                 250                 255

 Glu Asp Leu Phe Met Cys Met Asp Ile Gln Leu Val Glu Ala Leu
                 260                 265                 270

 Cys Gly Phe Gln Lys Pro Ile Ser Thr Leu Asp Asn Arg Thr Ile
                 275                 280                 285

 Val Ile Thr Ser His Pro Gly Gln Ile Val Lys His Gly Asp Ile
                 290                 295                 300

 Lys Cys Val Leu Asn Glu Gly Met Pro Ile Tyr Arg Arg Pro Tyr
                 305                 310                 315

 Glu Lys Gly Arg Leu Ile Ile Glu Phe Lys Val Asn Phe Pro Glu
                 320                 325                 330

 Asn Gly Phe Leu Ser Pro Asp Lys Leu Ser Leu Leu Glu Lys Leu
                 335                 340                 345

 Leu Pro Glu Arg Lys Glu Val Glu Glu Thr Asp Glu Met Asp Gln
                 350                 355                 360

 Val Glu Leu Val Asp Phe Asp Pro Asn Gln Glu Arg Arg Arg His
                 365                 370                 375

 Tyr Asn Gly Glu Ala Tyr Glu Asp Asp Glu His His Pro Arg Gly
                 380                 385                 390

 Gly Val Gln Cys Gln Thr Ser
                 395

<210> 123
<211> 3285
<212> DNA
<213> Homo sapien

<400> 123
 ctagaattca gcggccgctg aattctagac ccggatgaag agtaacgcca 50

 ttaccgcccg agccgccgag agccttagcc gacggaaact ggacactgga 100

 ccggcagcgc catgagactc ctcccccgct tgctgctgct tctcttactc 150

 gtgttccctg ccactgtctt gttccgaggc ggccccagag gctcgttagc 200

 agtggcacaa gatcttacag aggatgaaga aacagtagaa gattccataa 250

 ttgaggatga agatgatgaa gccgaggtag aagaagatga acccacagat 300

 ttggtagaag ataaagagga agaagatgtg tctggtgaac ctgaagcttc 350

 accgagtgca gatacaacta tactgtttgt aaaaggagaa gattttccag 400

 caaataacat tgtgaagttc ctggtaggct ttaccaacaa gggtacagaa 450

 gattttattg ttgaatcctt agatgcctca ttccgttatc ctcaggacca 500

 ccagttttat atccagaatt tcacagctct tcctctgaac actgtagtgc 550

 caccccagag acaggcaact tttgagtact ctttcattcc tgcagagccc 600

 atgggcggac gaccatttgg tttggtcatc aatctgaact acaaagattt 650

 gaacggcaat gtattccaag atgcagtctt caatcaaaca gttacagtta 700

 ttgaaagaga ggatgggtta gatggagaaa caatctttat gtatatgttc 750

 cttgctggtc ttgggcttct ggttattgtt ggccttcatc aactcctaga 800

 atctagaaag cgtaagagac ccatacagaa agtagaaatg ggtacatcaa 850

 gtcagaatga tgttgacatg agttggattc ctcaggaaac attgaatcaa 900

 atcaataaag cttcaccaag aaggttgccc aggaaacggg cacagaagag 950

 atcagtggga tctgatgagt aaatgttcct ttgtgcaaca attcggtctt 1000

 tacttaacct gccctaatat ttttcggcct gatgggaatt agtgcagaga 1050

 agccagtcac catagaaggc aactcctact tgtgtgtgga ctgagcaatc 1100

 agagtctgtg gcgataatat tgctgaaaat gcactgcatt catttttcta 1150

 aagtaacaaa tttggttttt ttttaaacca ttaaaatcta tgtgtgtgcg 1200

 tgtgtatgta tgtgagcagt tggtcttacc agaatcattg ttgaactacc 1250

 tgaaacaagt ctttagaata ctaaatataa tgctgttgtc tcttcctttt 1300

 tgacattttc tgattttttc ccccaaaact cagttaatat ttacccacta 1350

 tgattattga tgtcctgcct tgaacagttt taaagaaaac aatttttgga 1400

 atagctcaaa tttcaattga tggcacaaat cagcattttg ttgttgttac 1450

 tgtattacaa ttagtattct aaaggcagaa gcagaagtag ctgcttttta 1500

 gcaatagaat tgtttcagta ttttgctgct gtttaatgcg catcttcaga 1550

 aaacttccca gtggcttcaa ggaatttggg gatctctctg gcaacaaatt 1600

 gtgaaacatg aaatttctgc tgactttaat atatgaaacc taatcctacc 1650

 ccctttttta acaaaaagaa actagtacat ttgtgaaaat tgtgttgtgt 1700

 tgtccattgt tgctctagtt ctgacccaga ggtagctctg gagtgatttt 1750

 agacctactc actcagttgt gtgtaggttt ttttgttttg ttttgagaga 1800

 gaatttttct ctccttaata gaagcatcct ttttaaagag aagttgcctt 1850

 ggtccacaca ctaagcagaa aaccaagtta tcaggacaga gatatttccc 1900

 agttactcct aatcaatgaa gaaagtgagt tggatatttt taaagcagtt 1950

 aactaatttt ttcttaccta atcttttggg agttttgctt gttgatataa 2000

 cctttttagt taacctgaaa gattccaaaa attgttctta agtgcttgag 2050

 actggaacca aaattaaatt gtacttcata aaatcctctt atagagttac 2100

 tcttgcccta gattgtaaat taagtttggc attattgtca gactggatgg 2150

 agggtgaagt aaaatagtat gaacaattaa gaggctctcc ccctcttgtc 2200

 tttaagccat attctcctac atgtatttta taagaaaatg ttaagtcaaa 2250

 ttttagtggc tctttaattc ctgacctctt cattctcctt ttcagtataa 2300

 cctcccctat gctcatgccc acacagacaa aaaaacaaaa cgaaatacac 2350

 acagaaaaaa gtctttccaa actgtttaag tatttaaaca tctgagccaa 2400

 agcagataga agttattgta taattgttaa tcactttgca aataggggct 2450

 atcaaattac ctatattggc attgctggat tataaactct atatctgtaa 2500

 tataaagtgt ttgagttttt aattgggctg ttatgatcag taattgattt 2550

 tgagaaagct ctatgagctc taagtaactg catggttttt tgtttaatgt 2600

 aatataggag acccttcaca ttcccaagga atatattcca aaacattttt 2650

 gtgaatatct aagtttgtga aactactagg gcatgataca gtaaggtgta 2700

 attacagaat ttacgaaatg taaatggcct ctacagagtt ttatggaata 2750

 cctggtacta acgtaggcag ctgcaaaacc acactgagtt acagctgtca 2800

 gccctcctca ttcctaaata acttgcctta catatcagcc ctcccacttc 2850

 tgaagttcaa attagtgcct cggaaatgta gaatttatta tttgtcattt 2900

 ttttttttta gcatagattg agaacagttg aactcttaaa tcctcagatg 2950

 ccaggggtct gctctagcat cagtaagtat ttagcagaaa ctaactccgt 3000

 aatgaatgga attcaattcc acacatggtt tgttcaagca cacttaataa 3050

 gtagcctatt ttttaaatgt ctttttaaaa tgtaaatatt tggatgaagt 3100

 ttttctttgt tttgatatat tcatttgcta caccaactat gttttcagaa 3150

 ttcatctttt gaacaacttg gtttcagaat atgtaaaatg actttaagga 3200

 tcttgtgtat caaacctatc cccggatgtg tgagaataat gtgttcataa 3250

 agcatggatc tcgtaaaaaa aaaaaaaaaa aaaaa 3285

<210> 124
<211> 286
<212> PRT
<213> Homo sapien

<400> 124
 Met Arg Leu Leu Pro Arg Leu Leu Leu Leu Leu Leu Leu Val Phe
   1               5                  10                  15

 Pro Ala Thr Val Leu Phe Arg Gly Gly Pro Arg Gly Ser Leu Ala
                  20                  25                  30

 Val Ala Gln Asp Leu Thr Glu Asp Glu Glu Thr Val Glu Asp Ser
                  35                  40                  45

 Ile Ile Glu Asp Glu Asp Asp Glu Ala Glu Val Glu Glu Asp Glu
                  50                  55                  60

 Pro Thr Asp Leu Val Glu Asp Lys Glu Glu Glu Asp Val Ser Gly
                  65                  70                  75

 Glu Pro Glu Ala Ser Pro Ser Ala Asp Thr Thr Ile Leu Phe Val
                  80                  85                  90

 Lys Gly Glu Asp Phe Pro Ala Asn Asn Ile Val Lys Phe Leu Val
                  95                 100                 105

 Gly Phe Thr Asn Lys Gly Thr Glu Asp Phe Ile Val Glu Ser Leu
                 110                 115                 120

 Asp Ala Ser Phe Arg Tyr Pro Gln Asp His Gln Phe Tyr Ile Gln
                 125                 130                 135

 Asn Phe Thr Ala Leu Pro Leu Asn Thr Val Val Pro Pro Gln Arg
                 140                 145                 150

 Gln Ala Thr Phe Glu Tyr Ser Phe Ile Pro Ala Glu Pro Met Gly
                 155                 160                 165

 Gly Arg Pro Phe Gly Leu Val Ile Asn Leu Asn Tyr Lys Asp Leu
                 170                 175                 180

 Asn Gly Asn Val Phe Gln Asp Ala Val Phe Asn Gln Thr Val Thr
                 185                 190                 195

 Val Ile Glu Arg Glu Asp Gly Leu Asp Gly Glu Thr Ile Phe Met
                 200                 205                 210

 Tyr Met Phe Leu Ala Gly Leu Gly Leu Leu Val Ile Val Gly Leu
                 215                 220                 225

 His Gln Leu Leu Glu Ser Arg Lys Arg Lys Arg Pro Ile Gln Lys
                 230                 235                 240

 Val Glu Met Gly Thr Ser Ser Gln Asn Asp Val Asp Met Ser Trp
                 245                 250                 255

 Ile Pro Gln Glu Thr Leu Asn Gln Ile Asn Lys Ala Ser Pro Arg
                 260                 265                 270

 Arg Leu Pro Arg Lys Arg Ala Gln Lys Arg Ser Val Gly Ser Asp
                 275                 280                 285

 Glu


<210> 125
<211> 2251
<212> DNA
<213> Homo sapien

<400> 125
 gccgcgtgca gaggtgctca agcctcctcg cggtccgcag tcagtgccgc 50

 cgcgcccggc ctcccgcacg ccccgcaggt agcgcccccg cccgcggccc 100

 agagtgcgct cgcgccggca ccagctcccg gataaacggc gcgccgcgcg 150

 gagatgacag ccgaggagat gaaggcgacc gagagcgggg cgcagtcggc 200

 gccgctgccc atggagggag tggacatcag ccccaaacag gacgaaggcg 250

 tgctgaaggt catcaagaga gagggcacag gtacagagat gcccatgatt 300

 ggggaccgag tctttgtcca ctacactggc tggctattag atggcacaaa 350

 gtttgactcc agtctggatc gcaaggacaa attctccttt gacctgggaa 400

 aaggggaggt catcaaggct tgggacattg ccatagccac catgaaggtg 450

 ggggaggtgt gccacatcac ctgcaaacca gaatatgcct acggttcagc 500

 aggcagtcct ccaaagattc cccccaatgc cacgcttgta tttgaggtgg 550

 agttgtttga gtttaaggga gaagatctga cggaagagga agatggcgga 600

 atcattcgca gaatacagac tcgcggtgaa ggctatgcta agcccaatga 650

 gggtgctatc gtggaggttg cactggaagg gtactacaag gacaagctct 700

 ttgaccagcg ggagctccgc tttgagattg gcgaggggga gaacctggat 750

 ctgccttatg gtctggagag ggccattcag cgcatggaga aaggagaaca 800

 ttccatcgtg tacctcaagc ccagctatgc ttttggcagt gttgggaagg 850

 aaaagttcca aatcccacca aatgctgagc tgaaatatga attacacctc 900

 aagagttttg aaaaggccaa ggagtcttgg gagatgaatt cagaagagaa 950

 gctggaacag agcaccatag tgaaagagcg gggcactgtg tacttcaagg 1000

 aaggtaaata caagcaagct ttactacagt ataagaagat cgtgtcttgg 1050

 ctggaatatg agtctagttt ttccaatgag gaagcacaga aagcacaggc 1100

 ccttcgactg gcctctcacc tcaacctggc catgtgtcat ctgaaactac 1150

 aggccttctc tgctgccatt gaaagctgta acaaggccct agaactggac 1200

 agcaacaacg agaagggcct cttccgccgg ggagaggccc acctggccgt 1250

 gaatgacttt gaactggcac gggctgattt ccagaaggtc ctgcagctct 1300

 accccaacaa caaagccgcc aagacccagc tggctgtgtg ccagcagcgg 1350

 atccgaaggc agcttgcccg ggagaagaag ctctatgcca atatgtttga 1400

 gaggctggct gaggaggaga acaaggccaa ggcagaggct tcctcaggag 1450

 accatcccac tgacacagag atgaaggagg agcagaagag caacacggca 1500

 gggagccagt ctcaggtgga gacagaagca tagcccctct ccaccagccc 1550

 tactcctgcg gctgcctgcc ccccagtctc cccactccac cctgttagtt 1600

 ttgtaaaaac tgaagaattt tgagtgaatt agacctttat ttttctatct 1650

 ggttggatgg tggctttagg ggaaggggga aaggtgtagg ctgggggatt 1700

 gaggtgggga atcattttag ctggtgtcag cccctcttcc cttcctccat 1750

 tgcacatgaa catatgtcca tccatatata ttcatcagaa tgttaattta 1800

 ttttgctccc tctgttaggt ccattttcta agggtagaag aggcaagtgg 1850

 tagggatgag gtctgataag aacccagggt ggagagggag actcctgggc 1900

 agccgttttc ctcatccttt ccctctccca gtccatttcc aaatgtggcc 1950

 tccatgtggg tgctagggac atgggaaaaa ccactgctat gccatttctt 2000

 ctctctgttc ccttcctcac ccccgacggt gtggctgatg atgtcttctg 2050

 gtgtcatggt gaccaccccc tgttccctgt tctggtattt cccctgtcag 2100

 tttcccctct cggccaggtt gtgtcccaaa atcccctcag cctcttctct 2150

 gcacgttgct gaaggtccag gcttgcctca agttccatgc ttgagcaata 2200

 aagtggaaac aataaaacct gggtgtcaga caaaaaaaaa aaaaaaaaaa 2250

 a 2251

<210> 126
<211> 459
<212> PRT
<213> Homo sapien

<400> 126
 Met Thr Ala Glu Glu Met Lys Ala Thr Glu Ser Gly Ala Gln Ser
   1               5                  10                  15

 Ala Pro Leu Pro Met Glu Gly Val Asp Ile Ser Pro Lys Gln Asp
                  20                  25                  30

 Glu Gly Val Leu Lys Val Ile Lys Arg Glu Gly Thr Gly Thr Glu
                  35                  40                  45

 Met Pro Met Ile Gly Asp Arg Val Phe Val His Tyr Thr Gly Trp
                  50                  55                  60

 Leu Leu Asp Gly Thr Lys Phe Asp Ser Ser Leu Asp Arg Lys Asp
                  65                  70                  75

 Lys Phe Ser Phe Asp Leu Gly Lys Gly Glu Val Ile Lys Ala Trp
                  80                  85                  90

 Asp Ile Ala Ile Ala Thr Met Lys Val Gly Glu Val Cys His Ile
                  95                 100                 105

 Thr Cys Lys Pro Glu Tyr Ala Tyr Gly Ser Ala Gly Ser Pro Pro
                 110                 115                 120

 Lys Ile Pro Pro Asn Ala Thr Leu Val Phe Glu Val Glu Leu Phe
                 125                 130                 135

 Glu Phe Lys Gly Glu Asp Leu Thr Glu Glu Glu Asp Gly Gly Ile
                 140                 145                 150

 Ile Arg Arg Ile Gln Thr Arg Gly Glu Gly Tyr Ala Lys Pro Asn
                 155                 160                 165

 Glu Gly Ala Ile Val Glu Val Ala Leu Glu Gly Tyr Tyr Lys Asp
                 170                 175                 180

 Lys Leu Phe Asp Gln Arg Glu Leu Arg Phe Glu Ile Gly Glu Gly
                 185                 190                 195

 Glu Asn Leu Asp Leu Pro Tyr Gly Leu Glu Arg Ala Ile Gln Arg
                 200                 205                 210

 Met Glu Lys Gly Glu His Ser Ile Val Tyr Leu Lys Pro Ser Tyr
                 215                 220                 225

 Ala Phe Gly Ser Val Gly Lys Glu Lys Phe Gln Ile Pro Pro Asn
                 230                 235                 240

 Ala Glu Leu Lys Tyr Glu Leu His Leu Lys Ser Phe Glu Lys Ala
                 245                 250                 255

 Lys Glu Ser Trp Glu Met Asn Ser Glu Glu Lys Leu Glu Gln Ser
                 260                 265                 270

 Thr Ile Val Lys Glu Arg Gly Thr Val Tyr Phe Lys Glu Gly Lys
                 275                 280                 285

 Tyr Lys Gln Ala Leu Leu Gln Tyr Lys Lys Ile Val Ser Trp Leu
                 290                 295                 300

 Glu Tyr Glu Ser Ser Phe Ser Asn Glu Glu Ala Gln Lys Ala Gln
                 305                 310                 315

 Ala Leu Arg Leu Ala Ser His Leu Asn Leu Ala Met Cys His Leu
                 320                 325                 330

 Lys Leu Gln Ala Phe Ser Ala Ala Ile Glu Ser Cys Asn Lys Ala
                 335                 340                 345

 Leu Glu Leu Asp Ser Asn Asn Glu Lys Gly Leu Phe Arg Arg Gly
                 350                 355                 360

 Glu Ala His Leu Ala Val Asn Asp Phe Glu Leu Ala Arg Ala Asp
                 365                 370                 375

 Phe Gln Lys Val Leu Gln Leu Tyr Pro Asn Asn Lys Ala Ala Lys
                 380                 385                 390

 Thr Gln Leu Ala Val Cys Gln Gln Arg Ile Arg Arg Gln Leu Ala
                 395                 400                 405

 Arg Glu Lys Lys Leu Tyr Ala Asn Met Phe Glu Arg Leu Ala Glu
                 410                 415                 420

 Glu Glu Asn Lys Ala Lys Ala Glu Ala Ser Ser Gly Asp His Pro
                 425                 430                 435

 Thr Asp Thr Glu Met Lys Glu Glu Gln Lys Ser Asn Thr Ala Gly
                 440                 445                 450

 Ser Gln Ser Gln Val Glu Thr Glu Ala
                 455

<210> 127
<211> 2251
<212> DNA
<213> Homo sapien

<400> 127
 gccgcgtgca gaggtgctca agcctcctcg cggtccgcag tcagtgccgc 50

 cgcgcccggc ctcccgcacg ccccgcaggt agcgcccccg cccgcggccc 100

 agagtgcgct cgcgccggca ccagctcccg gataaacggc gcgccgcgcg 150

 gagatgacag ccgaggagat gaaggcgacc gagagcgggg cgcagtcggc 200

 gccgctgccc atggagggag tggacatcag ccccaaacag gacgaaggcg 250

 tgctgaaggt catcaagaga gagggcacag gtacagagat gcccatgatt 300

 ggggaccgag tctttgtcca ctacactggc tggctattag atggcacaaa 350

 gtttgactcc agtctggatc gcaaggacaa attctccttt gacctgggaa 400

 aaggggaggt catcaaggct tgggacattg ccatagccac catgaaggtg 450

 ggggaggtgt gccacatcac ctgcaaacca gaatatgcct acggttcagc 500

 aggcagtcct ccaaagattc cccccaatgc cacgcttgta tttgaggtgg 550

 agttgtttga gtttaaggga gaagatctga cggaagagga agatggcgga 600

 atcattcgca gaatacagac tcgcggtgaa ggctatgcta agcccaatga 650

 gggtgctatc gtggaggttg cactggaagg gtactacaag gacaagctct 700

 ttgaccagcg ggagctccgc tttgagattg gcgaggggga gaacctggat 750

 ctgccttatg gtctggagag ggccattcag cgcatggaga aaggagaaca 800

 ttccatcgtg tacctcaagc ccagctatgc ttttggcagt gttgggaagg 850

 aaaagttcca aatcccacca aatgctgagc tgaaatatga attacacctc 900

 aagagttttg aaaaggccaa ggagtcttgg gagatgaatt cagaagagaa 950

 gctggaacag agcaccatag tgaaagagcg gggcactgtg tacttcaagg 1000

 aaggtaaata caagcaagct ttactacagt ataagaagat cgtgtcttgg 1050

 ctggaatatg agtctagttt ttccaatgag gaagcacaga aagcacaggc 1100

 ccttcgactg gcctctcacc tcaacctggc catgtgtcat ctgaaactac 1150

 aggccttctc tgctgccatt gaaagctgta acaaggccct agaactggac 1200

 agcaacaacg agaagggcct cttccgccgg ggagaggccc acctggccgt 1250

 gaatgacttt gaactggcac gggctgattt ccagaaggtc ctgcagctct 1300

 accccaacaa caaagccgcc aagacccagc tggctgtgtg ccagcagcgg 1350

 atccgaaggc agcttgcccg ggagaagaag ctctatgcca atatgtttga 1400

 gaggctggct gaggaggaga acaaggccaa ggcagaggct tcctcaggag 1450

 accatcccac tgacacagag atgaaggagg agcagaagag caacacggca 1500

 gggagccagt ctcaggtgga gacagaagca tagcccctct ccaccagccc 1550

 tactcctgcg gctgcctgcc ccccagtctc cccactccac cctgttagtt 1600

 ttgtaaaaac tgaagaattt tgagtgaatt agacctttat ttttctatct 1650

 ggttggatgg tggctttagg ggaaggggga aaggtgtagg ctgggggatt 1700

 gaggtgggga atcattttag ctggtgtcag cccctcttcc cttcctccat 1750

 tgcacatgaa catatgtcca tccatatata ttcatcagaa tgttaattta 1800

 ttttgctccc tctgttaggt ccattttcta agggtagaag aggcaagtgg 1850

 tagggatgag gtctgataag aacccagggt ggagagggag actcctgggc 1900

 agccgttttc ctcatccttt ccctctccca gtccatttcc aaatgtggcc 1950

 tccatgtggg tgctagggac atgggaaaaa ccactgctat gccatttctt 2000

 ctctctgttc ccttcctcac ccccgacggt gtggctgatg atgtcttctg 2050

 gtgtcatggt gaccaccccc tgttccctgt tctggtattt cccctgtcag 2100

 tttcccctct cggccaggtt gtgtcccaaa atcccctcag cctcttctct 2150

 gcacgttgct gaaggtccag gcttgcctca agttccatgc ttgagcaata 2200

 aagtggaaac aataaaacct gggtgtcaga caaaaaaaaa aaaaaaaaaa 2250

 a 2251

<210> 128
<211> 459
<212> PRT
<213> Homo sapien

<400> 128
 Met Thr Ala Glu Glu Met Lys Ala Thr Glu Ser Gly Ala Gln Ser
   1               5                  10                  15

 Ala Pro Leu Pro Met Glu Gly Val Asp Ile Ser Pro Lys Gln Asp
                  20                  25                  30

 Glu Gly Val Leu Lys Val Ile Lys Arg Glu Gly Thr Gly Thr Glu
                  35                  40                  45

 Met Pro Met Ile Gly Asp Arg Val Phe Val His Tyr Thr Gly Trp
                  50                  55                  60

 Leu Leu Asp Gly Thr Lys Phe Asp Ser Ser Leu Asp Arg Lys Asp
                  65                  70                  75

 Lys Phe Ser Phe Asp Leu Gly Lys Gly Glu Val Ile Lys Ala Trp
                  80                  85                  90

 Asp Ile Ala Ile Ala Thr Met Lys Val Gly Glu Val Cys His Ile
                  95                 100                 105

 Thr Cys Lys Pro Glu Tyr Ala Tyr Gly Ser Ala Gly Ser Pro Pro
                 110                 115                 120

 Lys Ile Pro Pro Asn Ala Thr Leu Val Phe Glu Val Glu Leu Phe
                 125                 130                 135

 Glu Phe Lys Gly Glu Asp Leu Thr Glu Glu Glu Asp Gly Gly Ile
                 140                 145                 150

 Ile Arg Arg Ile Gln Thr Arg Gly Glu Gly Tyr Ala Lys Pro Asn
                 155                 160                 165

 Glu Gly Ala Ile Val Glu Val Ala Leu Glu Gly Tyr Tyr Lys Asp
                 170                 175                 180

 Lys Leu Phe Asp Gln Arg Glu Leu Arg Phe Glu Ile Gly Glu Gly
                 185                 190                 195

 Glu Asn Leu Asp Leu Pro Tyr Gly Leu Glu Arg Ala Ile Gln Arg
                 200                 205                 210

 Met Glu Lys Gly Glu His Ser Ile Val Tyr Leu Lys Pro Ser Tyr
                 215                 220                 225

 Ala Phe Gly Ser Val Gly Lys Glu Lys Phe Gln Ile Pro Pro Asn
                 230                 235                 240

 Ala Glu Leu Lys Tyr Glu Leu His Leu Lys Ser Phe Glu Lys Ala
                 245                 250                 255

 Lys Glu Ser Trp Glu Met Asn Ser Glu Glu Lys Leu Glu Gln Ser
                 260                 265                 270

 Thr Ile Val Lys Glu Arg Gly Thr Val Tyr Phe Lys Glu Gly Lys
                 275                 280                 285

 Tyr Lys Gln Ala Leu Leu Gln Tyr Lys Lys Ile Val Ser Trp Leu
                 290                 295                 300

 Glu Tyr Glu Ser Ser Phe Ser Asn Glu Glu Ala Gln Lys Ala Gln
                 305                 310                 315

 Ala Leu Arg Leu Ala Ser His Leu Asn Leu Ala Met Cys His Leu
                 320                 325                 330

 Lys Leu Gln Ala Phe Ser Ala Ala Ile Glu Ser Cys Asn Lys Ala
                 335                 340                 345

 Leu Glu Leu Asp Ser Asn Asn Glu Lys Gly Leu Phe Arg Arg Gly
                 350                 355                 360

 Glu Ala His Leu Ala Val Asn Asp Phe Glu Leu Ala Arg Ala Asp
                 365                 370                 375

 Phe Gln Lys Val Leu Gln Leu Tyr Pro Asn Asn Lys Ala Ala Lys
                 380                 385                 390

 Thr Gln Leu Ala Val Cys Gln Gln Arg Ile Arg Arg Gln Leu Ala
                 395                 400                 405

 Arg Glu Lys Lys Leu Tyr Ala Asn Met Phe Glu Arg Leu Ala Glu
                 410                 415                 420

 Glu Glu Asn Lys Ala Lys Ala Glu Ala Ser Ser Gly Asp His Pro
                 425                 430                 435

 Thr Asp Thr Glu Met Lys Glu Glu Gln Lys Ser Asn Thr Ala Gly
                 440                 445                 450

 Ser Gln Ser Gln Val Glu Thr Glu Ala
                 455

<210> 129
<211> 2376
<212> DNA
<213> Homo sapien

<400> 129
 gaggaggagt ggggaccggg cggggggtgg aggaagaggc ctcgcgcaga 50

 ggagggagca attgaatttc aaacacaaac aactcgacga gcgcgcaccc 100

 accgcgccgg agccttgccc cgatccgcgc ccgccccgtc cgtgcggcgc 150

 gcgggcggag acgccgtggc cgcgccggag ctcgggccgg gggccaccat 200

 cgaggcgggg gccgcgcgag ggccggagcg gagcggcgcc gccaccgccg 250

 cacgcgcaaa cttgggctcg cgcttcccgg cccggcgcgg agcccggggc 300

 gcccggagcc ccgccatgtc gcgatccaac cggcagaagg agtacaaatg 350

 cggggacctg gtgttcgcca agatgaaggg ctacccacac tggccggccc 400

 ggattgacga gatgcctgag gctgccgtga aatcaacagc caacaaatac 450

 caagtctttt ttttcgggac ccacgagacg gcattcctgg gccccaaaga 500

 cctcttccct tacgaggaat ccaaggagaa gtttggcaag cccaacaaga 550

 ggaaagggtt cagcgagggg ctgtgggaga tcgagaacaa ccctactgtc 600

 aaggcttccg gctatcagtc ctcccagaaa aagagctgtg tggaagagcc 650

 tgaaccagag cccgaagctg cagagggtga cggtgataag aaggggaatg 700

 cagagggcag cagcgacgag gaagggaagc tggtcattga tgagccagcc 750

 aaggagaaga acgagaaagg agcgttgaag aggagagcag gggacttgct 800

 ggaggactct cctaaacgtc ccaaggaggc agaaaaccct gaaggagagg 850

 agaaggaggc agccaccttg gaggttgaga ggccccttcc tatggaggtg 900

 gaaaagaata gcaccccctc tgagcccggc tctggccggg ggcctcccca 950

 agaggaagaa gaagaggagg atgaagagga agaggctacc aaggaagatg 1000

 ctgaggcccc aggcatcaga gatcatgaga gcctgtagcc accaatgttt 1050

 caagaggagc ccccaccctg ttcctgctgc tgtctgggtg ctactgggga 1100

 aactggccat ggcctgcaaa ctgggaaccc ctttcccacc ccaacctgct 1150

 ctcctcttct actcactttt cccactccaa gcccagccca tggagattga 1200

 cctggatggg gcaggccacc tggctctcac ctctaggtcc ccatactcct 1250

 atgatctgag tcagagccat gtcttctccc tggaatgagt tgaggccact 1300

 gtgttccttc cgcttggagc tattttccag gcttctgctg gggcctggga 1350

 caactgctcc cacctcctga cacccttctc ccactctcct aggcattctg 1400

 gacctctggg ttgggatcag gggtaggaat ggaaggatgg agcatcaaca 1450

 gcagggtggg cttgtggggc ctgggagggg caatcctcaa atgcggggtg 1500

 ggggcagcac aggagggcgg cctccttctg agctcctgtc ccctgctaca 1550

 cctattatcc cagctgccta gattcaggga aagtgggaca gcttgtaggg 1600

 gaggggctcc tttccataaa tccttgatga ttgacaacac ccatttttcc 1650

 ttttgccgac cccaagagtt ttgggagttg tagttaatca tcaagagaat 1700

 ttggggcttc caagttgttc gggccaagga cctgagacct gaagggttga 1750

 ctttacccat ttgggtggga gtgttgagca tctgtccccc tttagatctc 1800

 tgaagccaca aataggatgc ttgggaagac tcctagctgt cctttttcct 1850

 ctccacacag tgctcaaggc cagcttatag tcatatatat cacccagaca 1900

 taaaggaaaa gacacatttt ttaggaaatg tttttaataa aagaaaatta 1950

 caaaaaaaaa ttttaaagac ccctaaccct ttgtgtgctc tccattctgc 2000

 tccttcccca tcgttgcccc catttctgag gtgcactggg aggctcccct 2050

 tctatttggg gcttgatgac tttctttttg tagctggggc tttgatgttc 2100

 cttccagtgt catttctcat ccacataccc tgacctggcc ccctcagtgt 2150

 tgtcaccaga tctgatttgt aacccactga gaggacagag agaaataagt 2200

 gccctctccc accctcttcc tactggtctc tctatgcctc tctacagtct 2250

 cgtctctttt accctggccc ctctcccttg ggctctgatg aaaaattgct 2300

 gactgtagct ttggaagttt agctctgaga accgtagatg atttcagttc 2350

 taggaaaata aaacccgttg attact 2376

<210> 130
<211> 240
<212> PRT
<213> Homo sapien

<400> 130
 Met Ser Arg Ser Asn Arg Gln Lys Glu Tyr Lys Cys Gly Asp Leu
   1               5                  10                  15

 Val Phe Ala Lys Met Lys Gly Tyr Pro His Trp Pro Ala Arg Ile
                  20                  25                  30

 Asp Glu Met Pro Glu Ala Ala Val Lys Ser Thr Ala Asn Lys Tyr
                  35                  40                  45

 Gln Val Phe Phe Phe Gly Thr His Glu Thr Ala Phe Leu Gly Pro
                  50                  55                  60

 Lys Asp Leu Phe Pro Tyr Glu Glu Ser Lys Glu Lys Phe Gly Lys
                  65                  70                  75

 Pro Asn Lys Arg Lys Gly Phe Ser Glu Gly Leu Trp Glu Ile Glu
                  80                  85                  90

 Asn Asn Pro Thr Val Lys Ala Ser Gly Tyr Gln Ser Ser Gln Lys
                  95                 100                 105

 Lys Ser Cys Val Glu Glu Pro Glu Pro Glu Pro Glu Ala Ala Glu
                 110                 115                 120

 Gly Asp Gly Asp Lys Lys Gly Asn Ala Glu Gly Ser Ser Asp Glu
                 125                 130                 135

 Glu Gly Lys Leu Val Ile Asp Glu Pro Ala Lys Glu Lys Asn Glu
                 140                 145                 150

 Lys Gly Ala Leu Lys Arg Arg Ala Gly Asp Leu Leu Glu Asp Ser
                 155                 160                 165

 Pro Lys Arg Pro Lys Glu Ala Glu Asn Pro Glu Gly Glu Glu Lys
                 170                 175                 180

 Glu Ala Ala Thr Leu Glu Val Glu Arg Pro Leu Pro Met Glu Val
                 185                 190                 195

 Glu Lys Asn Ser Thr Pro Ser Glu Pro Gly Ser Gly Arg Gly Pro
                 200                 205                 210

 Pro Gln Glu Glu Glu Glu Glu Glu Asp Glu Glu Glu Glu Ala Thr
                 215                 220                 225

 Lys Glu Asp Ala Glu Ala Pro Gly Ile Arg Asp His Glu Ser Leu
                 230                 235                 240

<210> 131
<211> 5773
<212> DNA
<213> Homo sapien

<400> 131
 gtgaccacgg accaggcagt ctctaatgaa taggcaaggc cacaacctcc 50

 attctcccag aaaagaagaa atgctcatct gaaattcatc acctctctgg 100

 agtcttcaaa ctgaccaagc attgaaaaga acacagtttc agaaaacagt 150

 ttccagtgcc tctggccttc ctactgaaag cagacacaga gtgcatgaag 200

 accgttcaaa tatgtcaggg acctcctccc atgagtcctt ctatgactcc 250

 ctctcagaca tgcaggaaga aagcaagaat actgacttct tcccgggcct 300

 ttctgctttc ctcagccagg aagagataaa caagagtctt gacctggccc 350

 ggagagccat agccgactcc gaaacagaag attttgactc ggaaaaggag 400

 atctcgcaga ttttcagtac ttctcctgca agcctctgtg aacatccttc 450

 ccataaggag accaaattgg gtgaacacgc ctcgaggaga cctcaggata 500

 acaggtcaac acctgtccag cctctggcag agaaacaaac taagagtatc 550

 tcttcacctg tttcaaagag gaaacctgcc atgtcacccc tgctcaccag 600

 gcccagctac atccggagcc tccgaaaggc tgaaaagcgt ggtgcaaaaa 650

 ctcccagcac aaacgtaaag cccaaaacgc cacatcaaag aaagggtggc 700

 ccccagagcc agctgtgtga caaggcagct aatttaattg aggagctaac 750

 atccatattt aaagccgcaa agccaagaaa cagaagccca aatggggagt 800

 cctcgtcacc agacagtggg tacctgtctc ctaaaaatca gccgtcagcc 850

 ctgctgagtg cctcagccag ccagagccct atggaagacc aaggggagat 900

 ggaaagagag gtcaagtccc ctggggccag gcattgctac caggacaacc 950

 aggacttggc agtgccacac aaccgcaagt ctcacccaca gccccacagc 1000

 gccctccact tcccagctgc acctcgattc atccaaaagc tgaggagcca 1050

 agaagtagca gaagggagcc gagtttatct ggagtgtaga gtcactggaa 1100

 accccactcc tcgagtcaga tggttctgtg aagggaaaga actgcacaac 1150

 actcctgata ttcaaatcca ctgtgaggga ggggacctcc ataccctgat 1200

 catagcagag gcctttgagg acgacacagg tcgctacacc tgtttggcta 1250

 cgaatcccag cggctcagac acaacatctg ctgaggtgtt cattgaaggt 1300

 gccagttcaa cagattctga cagtgaaagt ttagctttca aatcaagagc 1350

 tggagctatg ccacaagctc aaaagaaaac aacttctgtt tccttgacaa 1400

 taggatcatc atctccaaag acaggggtga ccacagctgt gattcaacca 1450

 ctgtctgtcc ctgtgcaaca ggttcacagt ccaacttcat atctctgccg 1500

 acctgatgga accactactg cctactttcc tcctgttttt acaaaggaac 1550

 tgcaaaacac agccgtggcg gaaggccagg tggtggttct ggagtgccgg 1600

 gtccgtgggg caccccctct gcaggtccag tggtttcggc aagggagtga 1650

 aatccaagac tctccagatt tccgaattct acagaaaaaa cctagatcta 1700

 cagctgaacc tgaggagatt tgcaccctag ttatcgctga gactttccct 1750

 gaagatgcag ggatctttac atgttcagca agaaatgatt atggatcagc 1800

 aaccagcact gcccagctgg ttgtcacctc agccaacact gaaaactgta 1850

 gttacgagtc aatgggagaa tccaacaatg accacttcca acactttcca 1900

 cctccccctc caatcttgga gacaagttcc ttggagttgg cttcaaagaa 1950

 accatctgag atccagcagg tgaacaaccc tgagttaggc ctgagcaggg 2000

 cagcccttca aatgcaattc aatgctgctg agagggaaac gagcggagtc 2050

 catcccagcc gtggagtaaa tggactgatt aacggcaaag ctaacagtaa 2100

 taaatctctt ccaacaccag ctgtcctgct ttcacccact aaggagccac 2150

 cacctctgct tgccaaacca aaactaggat ttccaaagaa ggccagtaga 2200

 actgctagaa tagcctccga tgaggaaatt caaggcacaa aggatgctgt 2250

 tattcaagac ctggaacgaa aacttcgctt caaggaggac ctcctgaaca 2300

 atggccagcc gaggttaaca tacgaagaaa gaatggctcg tcgactgcta 2350

 ggtgctgaca gtgcaactgt ctttaatatt caggagccag aagaggaaac 2400

 agctaatcag gaatacaaag tctccagctg tgaacagaga ctcatcagtg 2450

 aaatagagta caggctagaa aggtctcctg tggatgaatc aggtgatgaa 2500

 gttcagtatg gagatgtgcc tgtggaaaat ggaatggcac cattctttga 2550

 gatgaagctg aaacattaca agatctttga gggaatgcca gtaactttca 2600

 catgtagagt ggctggaaat ccaaagccaa agatctattg gtttaaagat 2650

 gggaagcaga tctctccaaa gagtgatcac tacaccattc aaagagatct 2700

 cgatgggacc tgctccctcc ataccacagc ctccacccta gatgatgatg 2750

 ggaattatac aattatggct gcaaaccctc agggccgcat cagttgtact 2800

 ggacggctaa tggtacaggc tgtcaaccaa agaggtcgaa gtccccggtc 2850

 tccctcaggc catcctcatg tcagaaggcc tcgttctaga tcaagggaca 2900

 gtggagacga aaatgaacca attcaggagc gattcttcag acctcacttc 2950

 ttgcaggctc ctggagatct gactgttcaa gaaggaaaac tctgcagaat 3000

 ggactgcaaa gtcagtgggt taccaacccc agatctaagc tggcaactag 3050

 atggaaagcc cgtacgccct gacagtgctc acaagatgct ggtgcgtgag 3100

 aacggggtgc actctctgat catagagcca gtcacgtcac gtgatgccgg 3150

 catctacaca tgtatagcta ccaaccgagc aggacagaac tcattcagcc 3200

 tggagcttgt ggttgctgct aaagaagcac acaaaccccc tgtgtttatt 3250

 gagaagctcc aaaacacagg agttgctgat gggtacccag tgcggctgga 3300

 atgtcgtgta ttgggagtgc caccacctca gatattttgg aagaaagaaa 3350

 atgaatcact cactcacagc actgaccgag tgagcatgca ccaggacaac 3400

 cacggctaca tctgcctgct cattcaggga gccacaaaag aagatgctgg 3450

 gtggtatact gtgtcagcca agaatgaagc agggattgtg tcctgtactg 3500

 ccaggctgga cgtttacatt tctcgacatt aatagtgaac cacaccagga 3550

 gaacaaatac ccaacccagt ggcatcagca gtcacagagc accaagccaa 3600

 aaaaagtacg gccctcagcc agtcgctatg cagcactttc ggaccaggga 3650

 ctagacatca aagcagcgtt ccaacctgag gccaacccat ctcacctgac 3700

 actgaatact gccttggtag aaagtgagga cctgtaatcc agcattcttg 3750

 ttaaagctga aacactgaaa cagccattgc cttgaccaac atattccttt 3800

 gtcacattat gtaaaaggca gaaacatacc tttgactata agaaattaaa 3850

 aaaaaacacc aaaataatat ttttcttact tgatatacca aacttagttt 3900

 aagtagataa tgctaataca aatatacaca ttgcacagaa aatacacatt 3950

 tactgtccaa tttaaaactt tggaattgct gtgattaaag tgatcaaaat 4000

 gccaaaatac taaaggaaat caattgttca caggtaacta caatttgtat 4050

 tatctacaag tgcctttaaa cacaagatat aggtgctgtg tagcctgata 4100

 gtgtgaaatg tttaatgagg gagttgtacc acaaacagta ctacaatgat 4150

 tctgaagcac agtgtattca gacagataca gtgaaccaag tgcaatatgt 4200

 aaggatgaaa gaagaagaga tgacaaagaa rtccaagtaa atgccttgtc 4250

 tttgcaaatg tttttatatt aaatcataag gaaggaacta cttgccttaa 4300

 atgttaatat caaaagagtt ttctaacaag gttaatacct tagttcttaa 4350

 catttttttt ctttatgtgt agtgttttca tgctaccttg gtaggaaact 4400

 tatttacaaa ccatattaaa aggctaattt aaatataaat aatataaagt 4450

 gctctgaata aagcagaaat atattacagt tcattccaca gaaagcatcc 4500

 aaaccaccca aatgaccaag gcatatatag tatttggagg aatcaggggt 4550

 ttggaaggag tagggaggag aatgaaggaa artgcaacca gcatgattat 4600

 agtgtgttca tttagataaa agtagaaggc acaggagagg tagcaaaggc 4650

 caggcttttc tttggttttc ttcaaacata ggtgaaaaaa acactgccat 4700

 tcacaagtca aggaacccag ggccagctgg aagtgtggag cacacatgct 4750

 gtggagcaca catgctgtgg agattgcagt gtgtctgagg tttgtgtagt 4800

 agtggaagat tttaggtatg tagagcaagt tgaaaatgga ttgagactgc 4850

 atggtggcat aaatgagaaa ttgcctgtag catctagtct acttgaagga 4900

 agtggagaca taaggagaga caaaaacagg tttgtgccat aaagtatttt 4950

 ttcaaagaca ccaagatgtg gtaaatgaaa attattagtt cacttccctg 5000

 ctgccatgaa actttgcctt aagaaggtgc tggattccaa ggtttgtaaa 5050

 ggcatctcgg taaagactgc tttttgaatg catatgattt tgcatcagct 5100

 agactgagtt gattctgacc agacttgatg gttttaagtc ggaaccgata 5150

 aattttaaaa aggagaaaaa ataatttgac ctagtagtat aaaacatgag 5200

 gctttaatgg tactttgcta tgaaaagaaa acactgtatt ccttatgcaa 5250

 aacacatgta tctttcatta tttataagtg gcctctctta gctcagttac 5300

 tcaattcata cgtaatattt tttaaaataa ttttatatct gtgtaccacc 5350

 ccatatattt catattactg tttcacatgt acagctttct acttctttgt 5400

 aagaacacca accaaccaag gtttaagtga ttaataggct tgagcaccgg 5450

 gtggcagatg ttctatgcag tgtggttcaa gtttctttga ccgcacttat 5500

 atgcattgct agtatggaat ttaagatacc atacacagtc tctcatggac 5550

 ctatctctat tgtagaatta tgacttatgt cttacttggc aaatttttct 5600

 gaatgtgacc tttttttgct gatttgctgg gtttgggatt aactagcatt 5650

 attttgccac ctttatattg tatttataaa aaaaagtact atcaatcaat 5700

 catactactt tggattgttg tgctggtgta atgtggattt aacatcaata 5750

 aatatttgac aaataaaaaa aaa 5773

<210> 132
<211> 1106
<212> PRT
<213> Homo sapien

<400> 132
 Met Ser Gly Thr Ser Ser His Glu Ser Phe Tyr Asp Ser Leu Ser
   1               5                  10                  15

 Asp Met Gln Glu Glu Ser Lys Asn Thr Asp Phe Phe Pro Gly Leu
                  20                  25                  30

 Ser Ala Phe Leu Ser Gln Glu Glu Ile Asn Lys Ser Leu Asp Leu
                  35                  40                  45

 Ala Arg Arg Ala Ile Ala Asp Ser Glu Thr Glu Asp Phe Asp Ser
                  50                  55                  60

 Glu Lys Glu Ile Ser Gln Ile Phe Ser Thr Ser Pro Ala Ser Leu
                  65                  70                  75

 Cys Glu His Pro Ser His Lys Glu Thr Lys Leu Gly Glu His Ala
                  80                  85                  90

 Ser Arg Arg Pro Gln Asp Asn Arg Ser Thr Pro Val Gln Pro Leu
                  95                 100                 105

 Ala Glu Lys Gln Thr Lys Ser Ile Ser Ser Pro Val Ser Lys Arg
                 110                 115                 120

 Lys Pro Ala Met Ser Pro Leu Leu Thr Arg Pro Ser Tyr Ile Arg
                 125                 130                 135

 Ser Leu Arg Lys Ala Glu Lys Arg Gly Ala Lys Thr Pro Ser Thr
                 140                 145                 150

 Asn Val Lys Pro Lys Thr Pro His Gln Arg Lys Gly Gly Pro Gln
                 155                 160                 165

 Ser Gln Leu Cys Asp Lys Ala Ala Asn Leu Ile Glu Glu Leu Thr
                 170                 175                 180

 Ser Ile Phe Lys Ala Ala Lys Pro Arg Asn Arg Ser Pro Asn Gly
                 185                 190                 195

 Glu Ser Ser Ser Pro Asp Ser Gly Tyr Leu Ser Pro Lys Asn Gln
                 200                 205                 210

 Pro Ser Ala Leu Leu Ser Ala Ser Ala Ser Gln Ser Pro Met Glu
                 215                 220                 225

 Asp Gln Gly Glu Met Glu Arg Glu Val Lys Ser Pro Gly Ala Arg
                 230                 235                 240

 His Cys Tyr Gln Asp Asn Gln Asp Leu Ala Val Pro His Asn Arg
                 245                 250                 255

 Lys Ser His Pro Gln Pro His Ser Ala Leu His Phe Pro Ala Ala
                 260                 265                 270

 Pro Arg Phe Ile Gln Lys Leu Arg Ser Gln Glu Val Ala Glu Gly
                 275                 280                 285

 Ser Arg Val Tyr Leu Glu Cys Arg Val Thr Gly Asn Pro Thr Pro
                 290                 295                 300

 Arg Val Arg Trp Phe Cys Glu Gly Lys Glu Leu His Asn Thr Pro
                 305                 310                 315

 Asp Ile Gln Ile His Cys Glu Gly Gly Asp Leu His Thr Leu Ile
                 320                 325                 330

 Ile Ala Glu Ala Phe Glu Asp Asp Thr Gly Arg Tyr Thr Cys Leu
                 335                 340                 345

 Ala Thr Asn Pro Ser Gly Ser Asp Thr Thr Ser Ala Glu Val Phe
                 350                 355                 360

 Ile Glu Gly Ala Ser Ser Thr Asp Ser Asp Ser Glu Ser Leu Ala
                 365                 370                 375

 Phe Lys Ser Arg Ala Gly Ala Met Pro Gln Ala Gln Lys Lys Thr
                 380                 385                 390

 Thr Ser Val Ser Leu Thr Ile Gly Ser Ser Ser Pro Lys Thr Gly
                 395                 400                 405

 Val Thr Thr Ala Val Ile Gln Pro Leu Ser Val Pro Val Gln Gln
                 410                 415                 420

 Val His Ser Pro Thr Ser Tyr Leu Cys Arg Pro Asp Gly Thr Thr
                 425                 430                 435

 Thr Ala Tyr Phe Pro Pro Val Phe Thr Lys Glu Leu Gln Asn Thr
                 440                 445                 450

 Ala Val Ala Glu Gly Gln Val Val Val Leu Glu Cys Arg Val Arg
                 455                 460                 465

 Gly Ala Pro Pro Leu Gln Val Gln Trp Phe Arg Gln Gly Ser Glu
                 470                 475                 480

 Ile Gln Asp Ser Pro Asp Phe Arg Ile Leu Gln Lys Lys Pro Arg
                 485                 490                 495

 Ser Thr Ala Glu Pro Glu Glu Ile Cys Thr Leu Val Ile Ala Glu
                 500                 505                 510

 Thr Phe Pro Glu Asp Ala Gly Ile Phe Thr Cys Ser Ala Arg Asn
                 515                 520                 525

 Asp Tyr Gly Ser Ala Thr Ser Thr Ala Gln Leu Val Val Thr Ser
                 530                 535                 540

 Ala Asn Thr Glu Asn Cys Ser Tyr Glu Ser Met Gly Glu Ser Asn
                 545                 550                 555

 Asn Asp His Phe Gln His Phe Pro Pro Pro Pro Pro Ile Leu Glu
                 560                 565                 570

 Thr Ser Ser Leu Glu Leu Ala Ser Lys Lys Pro Ser Glu Ile Gln
                 575                 580                 585

 Gln Val Asn Asn Pro Glu Leu Gly Leu Ser Arg Ala Ala Leu Gln
                 590                 595                 600

 Met Gln Phe Asn Ala Ala Glu Arg Glu Thr Ser Gly Val His Pro
                 605                 610                 615

 Ser Arg Gly Val Asn Gly Leu Ile Asn Gly Lys Ala Asn Ser Asn
                 620                 625                 630

 Lys Ser Leu Pro Thr Pro Ala Val Leu Leu Ser Pro Thr Lys Glu
                 635                 640                 645

 Pro Pro Pro Leu Leu Ala Lys Pro Lys Leu Gly Phe Pro Lys Lys
                 650                 655                 660

 Ala Ser Arg Thr Ala Arg Ile Ala Ser Asp Glu Glu Ile Gln Gly
                 665                 670                 675

 Thr Lys Asp Ala Val Ile Gln Asp Leu Glu Arg Lys Leu Arg Phe
                 680                 685                 690

 Lys Glu Asp Leu Leu Asn Asn Gly Gln Pro Arg Leu Thr Tyr Glu
                 695                 700                 705

 Glu Arg Met Ala Arg Arg Leu Leu Gly Ala Asp Ser Ala Thr Val
                 710                 715                 720

 Phe Asn Ile Gln Glu Pro Glu Glu Glu Thr Ala Asn Gln Glu Tyr
                 725                 730                 735

 Lys Val Ser Ser Cys Glu Gln Arg Leu Ile Ser Glu Ile Glu Tyr
                 740                 745                 750

 Arg Leu Glu Arg Ser Pro Val Asp Glu Ser Gly Asp Glu Val Gln
                 755                 760                 765

 Tyr Gly Asp Val Pro Val Glu Asn Gly Met Ala Pro Phe Phe Glu
                 770                 775                 780

 Met Lys Leu Lys His Tyr Lys Ile Phe Glu Gly Met Pro Val Thr
                 785                 790                 795

 Phe Thr Cys Arg Val Ala Gly Asn Pro Lys Pro Lys Ile Tyr Trp
                 800                 805                 810

 Phe Lys Asp Gly Lys Gln Ile Ser Pro Lys Ser Asp His Tyr Thr
                 815                 820                 825

 Ile Gln Arg Asp Leu Asp Gly Thr Cys Ser Leu His Thr Thr Ala
                 830                 835                 840

 Ser Thr Leu Asp Asp Asp Gly Asn Tyr Thr Ile Met Ala Ala Asn
                 845                 850                 855

 Pro Gln Gly Arg Ile Ser Cys Thr Gly Arg Leu Met Val Gln Ala
                 860                 865                 870

 Val Asn Gln Arg Gly Arg Ser Pro Arg Ser Pro Ser Gly His Pro
                 875                 880                 885

 His Val Arg Arg Pro Arg Ser Arg Ser Arg Asp Ser Gly Asp Glu
                 890                 895                 900

 Asn Glu Pro Ile Gln Glu Arg Phe Phe Arg Pro His Phe Leu Gln
                 905                 910                 915

 Ala Pro Gly Asp Leu Thr Val Gln Glu Gly Lys Leu Cys Arg Met
                 920                 925                 930

 Asp Cys Lys Val Ser Gly Leu Pro Thr Pro Asp Leu Ser Trp Gln
                 935                 940                 945

 Leu Asp Gly Lys Pro Val Arg Pro Asp Ser Ala His Lys Met Leu
                 950                 955                 960

 Val Arg Glu Asn Gly Val His Ser Leu Ile Ile Glu Pro Val Thr
                 965                 970                 975

 Ser Arg Asp Ala Gly Ile Tyr Thr Cys Ile Ala Thr Asn Arg Ala
                 980                 985                 990

 Gly Gln Asn Ser Phe Ser Leu Glu Leu Val Val Ala Ala Lys Glu
                 995                1000                1005

 Ala His Lys Pro Pro Val Phe Ile Glu Lys Leu Gln Asn Thr Gly
                1010                1015                1020

 Val Ala Asp Gly Tyr Pro Val Arg Leu Glu Cys Arg Val Leu Gly
                1025                1030                1035

 Val Pro Pro Pro Gln Ile Phe Trp Lys Lys Glu Asn Glu Ser Leu
                1040                1045                1050

 Thr His Ser Thr Asp Arg Val Ser Met His Gln Asp Asn His Gly
                1055                1060                1065

 Tyr Ile Cys Leu Leu Ile Gln Gly Ala Thr Lys Glu Asp Ala Gly
                1070                1075                1080

 Trp Tyr Thr Val Ser Ala Lys Asn Glu Ala Gly Ile Val Ser Cys
                1085                1090                1095

 Thr Ala Arg Leu Asp Val Tyr Ile Ser Arg His
                1100                1105

<210> 133
<211> 1692
<212> DNA
<213> Homo sapien

<400> 133
 atacacgtgc catgtgcagc atgaggggct acccgagccc gtcaccctga 50

 gatggaagcc ggcttcccag cccaccatcc ccatcgtggg catcattgct 100

 ggcctggttc tccttggatc tgtggtctct ggagctgtgg ttgctgctgt 150

 gatatggagg aagaagagct caggtggaaa aggagggagc tactctaagg 200

 ctgagtggag cgacagtgcc caggggtctg agtctcacag cttgtaaagc 250

 ctgagacagc tgccttgtgt gcgactgaga tgcacagctg ccttgtgtgc 300

 gactgagatg caggatttcc tcacgcctcc cctatgtgtc ttaggggact 350

 ctggcttctc tttttgcaag ggcctctgaa tctgtctgtg tccctgttag 400

 cacaatgtga ggaggtagag aaacagtcca cctctgtgtc taccatgacc 450

 cccttcctca cactgacctg tgttccttcc ctgttctctt ttctattaaa 500

 aataagaacc tgggcagagt gcggcagctc atgcctgtaa tcccagcact 550

 tagggaggcc gaggagggca gatcacgagg tcaggagatc gaaaccatcc 600

 tggctaacac ggtgaaaccc cgtctctact aaaaaataca aaaaattagc 650

 tgggcgcaga ggcacgggcc tgtagtccca gctactcagg aggcggaggc 700

 aggagaatgg cgtcaacccg ggaggcggag gttgcagtga gccaggattg 750

 tgcgactgca ctccagcctg ggtgacaggg tgaaacgcca tctcaaaaaa 800

 taaaaattaa aaaataaaaa aagaacctgg atctcaattt aatttttcat 850

 attcttgcaa tgaaatggac ttgaggaagc taagatcata gctagaaata 900

 cagataattc cacagcacat ctctagcaaa tttagcctat tcctattctc 950

 tagcctattc cttaccacct gtaatcttga ccatatacct tggagttgaa 1000

 tattgttttc atactgctgt ggtttgaatg ttccctccaa cactcatgtt 1050

 gagacttaat ccctaatgtg gcaatactga aaggtggggc ctttgagatg 1100

 tgattggatc gtaaggctgt gccttcattc atgggttaat ggattaatgg 1150

 gttatcacag gaatgggact ggtggcttta taagaagagg aaaagagaac 1200

 tgagctagca tgcccaaccc acagagagcc tccactagag tgatgctaag 1250

 tggaaatgtg aggtgcagct gccacagagg gcccccacca gggaaatgtc 1300

 tagtgtctag tggatccagg ccacaggaga gagtgccttg tggagcgctg 1350

 ggagcaggac ctgaccacca ccaggacccc agaactgtgg agtcagtggc 1400

 agcatgcagc gcccccttgg gaaagcttta ggcaccagcc tgcaacccat 1450

 tcgagcagcc acgtaggctc gacccagcaa agccacaggc acggggctac 1500

 ctgaggcctt gggggccaat ccctgctcca gtgtgtccgt gaggcagcac 1550

 acgaagtcaa aagagattat ctcttcccac agataccttt tctctcccat 1600

 gaccctttaa cagcatctgc ttcattcccc tcaccttccc aggctgatct 1650

 gaggtaaact ttgaagtaaa ataaaagctg tgtttgagca tc 1692

<210> 134
<211> 5773
<212> DNA
<213> Homo sapien

<400> 134
 gtgaccacgg accaggcagt ctctaatgaa taggcaaggc cacaacctcc 50

 attctcccag aaaagaagaa atgctcatct gaaattcatc acctctctgg 100

 agtcttcaaa ctgaccaagc attgaaaaga acacagtttc agaaaacagt 150

 ttccagtgcc tctggccttc ctactgaaag cagacacaga gtgcatgaag 200

 accgttcaaa tatgtcaggg acctcctccc atgagtcctt ctatgactcc 250

 ctctcagaca tgcaggaaga aagcaagaat actgacttct tcccgggcct 300

 ttctgctttc ctcagccagg aagagataaa caagagtctt gacctggccc 350

 ggagagccat agccgactcc gaaacagaag attttgactc ggaaaaggag 400

 atctcgcaga ttttcagtac ttctcctgca agcctctgtg aacatccttc 450

 ccataaggag accaaattgg gtgaacacgc ctcgaggaga cctcaggata 500

 acaggtcaac acctgtccag cctctggcag agaaacaaac taagagtatc 550

 tcttcacctg tttcaaagag gaaacctgcc atgtcacccc tgctcaccag 600

 gcccagctac atccggagcc tccgaaaggc tgaaaagcgt ggtgcaaaaa 650

 ctcccagcac aaacgtaaag cccaaaacgc cacatcaaag aaagggtggc 700

 ccccagagcc agctgtgtga caaggcagct aatttaattg aggagctaac 750

 atccatattt aaagccgcaa agccaagaaa cagaagccca aatggggagt 800

 cctcgtcacc agacagtggg tacctgtctc ctaaaaatca gccgtcagcc 850

 ctgctgagtg cctcagccag ccagagccct atggaagacc aaggggagat 900

 ggaaagagag gtcaagtccc ctggggccag gcattgctac caggacaacc 950

 aggacttggc agtgccacac aaccgcaagt ctcacccaca gccccacagc 1000

 gccctccact tcccagctgc acctcgattc atccaaaagc tgaggagcca 1050

 agaagtagca gaagggagcc gagtttatct ggagtgtaga gtcactggaa 1100

 accccactcc tcgagtcaga tggttctgtg aagggaaaga actgcacaac 1150

 actcctgata ttcaaatcca ctgtgaggga ggggacctcc ataccctgat 1200

 catagcagag gcctttgagg acgacacagg tcgctacacc tgtttggcta 1250

 cgaatcccag cggctcagac acaacatctg ctgaggtgtt cattgaaggt 1300

 gccagttcaa cagattctga cagtgaaagt ttagctttca aatcaagagc 1350

 tggagctatg ccacaagctc aaaagaaaac aacttctgtt tccttgacaa 1400

 taggatcatc atctccaaag acaggggtga ccacagctgt gattcaacca 1450

 ctgtctgtcc ctgtgcaaca ggttcacagt ccaacttcat atctctgccg 1500

 acctgatgga accactactg cctactttcc tcctgttttt acaaaggaac 1550

 tgcaaaacac agccgtggcg gaaggccagg tggtggttct ggagtgccgg 1600

 gtccgtgggg caccccctct gcaggtccag tggtttcggc aagggagtga 1650

 aatccaagac tctccagatt tccgaattct acagaaaaaa cctagatcta 1700

 cagctgaacc tgaggagatt tgcaccctag ttatcgctga gactttccct 1750

 gaagatgcag ggatctttac atgttcagca agaaatgatt atggatcagc 1800

 aaccagcact gcccagctgg ttgtcacctc agccaacact gaaaactgta 1850

 gttacgagtc aatgggagaa tccaacaatg accacttcca acactttcca 1900

 cctccccctc caatcttgga gacaagttcc ttggagttgg cttcaaagaa 1950

 accatctgag atccagcagg tgaacaaccc tgagttaggc ctgagcaggg 2000

 cagcccttca aatgcaattc aatgctgctg agagggaaac gagcggagtc 2050

 catcccagcc gtggagtaaa tggactgatt aacggcaaag ctaacagtaa 2100

 taaatctctt ccaacaccag ctgtcctgct ttcacccact aaggagccac 2150

 cacctctgct tgccaaacca aaactaggat ttccaaagaa ggccagtaga 2200

 actgctagaa tagcctccga tgaggaaatt caaggcacaa aggatgctgt 2250

 tattcaagac ctggaacgaa aacttcgctt caaggaggac ctcctgaaca 2300

 atggccagcc gaggttaaca tacgaagaaa gaatggctcg tcgactgcta 2350

 ggtgctgaca gtgcaactgt ctttaatatt caggagccag aagaggaaac 2400

 agctaatcag gaatacaaag tctccagctg tgaacagaga ctcatcagtg 2450

 aaatagagta caggctagaa aggtctcctg tggatgaatc aggtgatgaa 2500

 gttcagtatg gagatgtgcc tgtggaaaat ggaatggcac cattctttga 2550

 gatgaagctg aaacattaca agatctttga gggaatgcca gtaactttca 2600

 catgtagagt ggctggaaat ccaaagccaa agatctattg gtttaaagat 2650

 gggaagcaga tctctccaaa gagtgatcac tacaccattc aaagagatct 2700

 cgatgggacc tgctccctcc ataccacagc ctccacccta gatgatgatg 2750

 ggaattatac aattatggct gcaaaccctc agggccgcat cagttgtact 2800

 ggacggctaa tggtacaggc tgtcaaccaa agaggtcgaa gtccccggtc 2850

 tccctcaggc catcctcatg tcagaaggcc tcgttctaga tcaagggaca 2900

 gtggagacga aaatgaacca attcaggagc gattcttcag acctcacttc 2950

 ttgcaggctc ctggagatct gactgttcaa gaaggaaaac tctgcagaat 3000

 ggactgcaaa gtcagtgggt taccaacccc agatctaagc tggcaactag 3050

 atggaaagcc cgtacgccct gacagtgctc acaagatgct ggtgcgtgag 3100

 aacggggtgc actctctgat catagagcca gtcacgtcac gtgatgccgg 3150

 catctacaca tgtatagcta ccaaccgagc aggacagaac tcattcagcc 3200

 tggagcttgt ggttgctgct aaagaagcac acaaaccccc tgtgtttatt 3250

 gagaagctcc aaaacacagg agttgctgat gggtacccag tgcggctgga 3300

 atgtcgtgta ttgggagtgc caccacctca gatattttgg aagaaagaaa 3350

 atgaatcact cactcacagc actgaccgag tgagcatgca ccaggacaac 3400

 cacggctaca tctgcctgct cattcaggga gccacaaaag aagatgctgg 3450

 gtggtatact gtgtcagcca agaatgaagc agggattgtg tcctgtactg 3500

 ccaggctgga cgtttacatt tctcgacatt aatagtgaac cacaccagga 3550

 gaacaaatac ccaacccagt ggcatcagca gtcacagagc accaagccaa 3600

 aaaaagtacg gccctcagcc agtcgctatg cagcactttc ggaccaggga 3650

 ctagacatca aagcagcgtt ccaacctgag gccaacccat ctcacctgac 3700

 actgaatact gccttggtag aaagtgagga cctgtaatcc agcattcttg 3750

 ttaaagctga aacactgaaa cagccattgc cttgaccaac atattccttt 3800

 gtcacattat gtaaaaggca gaaacatacc tttgactata agaaattaaa 3850

 aaaaaacacc aaaataatat ttttcttact tgatatacca aacttagttt 3900

 aagtagataa tgctaataca aatatacaca ttgcacagaa aatacacatt 3950

 tactgtccaa tttaaaactt tggaattgct gtgattaaag tgatcaaaat 4000

 gccaaaatac taaaggaaat caattgttca caggtaacta caatttgtat 4050

 tatctacaag tgcctttaaa cacaagatat aggtgctgtg tagcctgata 4100

 gtgtgaaatg tttaatgagg gagttgtacc acaaacagta ctacaatgat 4150

 tctgaagcac agtgtattca gacagataca gtgaaccaag tgcaatatgt 4200

 aaggatgaaa gaagaagaga tgacaaagaa rtccaagtaa atgccttgtc 4250

 tttgcaaatg tttttatatt aaatcataag gaaggaacta cttgccttaa 4300

 atgttaatat caaaagagtt ttctaacaag gttaatacct tagttcttaa 4350

 catttttttt ctttatgtgt agtgttttca tgctaccttg gtaggaaact 4400

 tatttacaaa ccatattaaa aggctaattt aaatataaat aatataaagt 4450

 gctctgaata aagcagaaat atattacagt tcattccaca gaaagcatcc 4500

 aaaccaccca aatgaccaag gcatatatag tatttggagg aatcaggggt 4550

 ttggaaggag tagggaggag aatgaaggaa artgcaacca gcatgattat 4600

 agtgtgttca tttagataaa agtagaaggc acaggagagg tagcaaaggc 4650

 caggcttttc tttggttttc ttcaaacata ggtgaaaaaa acactgccat 4700

 tcacaagtca aggaacccag ggccagctgg aagtgtggag cacacatgct 4750

 gtggagcaca catgctgtgg agattgcagt gtgtctgagg tttgtgtagt 4800

 agtggaagat tttaggtatg tagagcaagt tgaaaatgga ttgagactgc 4850

 atggtggcat aaatgagaaa ttgcctgtag catctagtct acttgaagga 4900

 agtggagaca taaggagaga caaaaacagg tttgtgccat aaagtatttt 4950

 ttcaaagaca ccaagatgtg gtaaatgaaa attattagtt cacttccctg 5000

 ctgccatgaa actttgcctt aagaaggtgc tggattccaa ggtttgtaaa 5050

 ggcatctcgg taaagactgc tttttgaatg catatgattt tgcatcagct 5100

 agactgagtt gattctgacc agacttgatg gttttaagtc ggaaccgata 5150

 aattttaaaa aggagaaaaa ataatttgac ctagtagtat aaaacatgag 5200

 gctttaatgg tactttgcta tgaaaagaaa acactgtatt ccttatgcaa 5250

 aacacatgta tctttcatta tttataagtg gcctctctta gctcagttac 5300

 tcaattcata cgtaatattt tttaaaataa ttttatatct gtgtaccacc 5350

 ccatatattt catattactg tttcacatgt acagctttct acttctttgt 5400

 aagaacacca accaaccaag gtttaagtga ttaataggct tgagcaccgg 5450

 gtggcagatg ttctatgcag tgtggttcaa gtttctttga ccgcacttat 5500

 atgcattgct agtatggaat ttaagatacc atacacagtc tctcatggac 5550

 ctatctctat tgtagaatta tgacttatgt cttacttggc aaatttttct 5600

 gaatgtgacc tttttttgct gatttgctgg gtttgggatt aactagcatt 5650

 attttgccac ctttatattg tatttataaa aaaaagtact atcaatcaat 5700

 catactactt tggattgttg tgctggtgta atgtggattt aacatcaata 5750

 aatatttgac aaataaaaaa aaa 5773

<210> 135
<211> 1106
<212> PRT
<213> Homo sapien

<400> 135
 Met Ser Gly Thr Ser Ser His Glu Ser Phe Tyr Asp Ser Leu Ser
   1               5                  10                  15

 Asp Met Gln Glu Glu Ser Lys Asn Thr Asp Phe Phe Pro Gly Leu
                  20                  25                  30

 Ser Ala Phe Leu Ser Gln Glu Glu Ile Asn Lys Ser Leu Asp Leu
                  35                  40                  45

 Ala Arg Arg Ala Ile Ala Asp Ser Glu Thr Glu Asp Phe Asp Ser
                  50                  55                  60

 Glu Lys Glu Ile Ser Gln Ile Phe Ser Thr Ser Pro Ala Ser Leu
                  65                  70                  75

 Cys Glu His Pro Ser His Lys Glu Thr Lys Leu Gly Glu His Ala
                  80                  85                  90

 Ser Arg Arg Pro Gln Asp Asn Arg Ser Thr Pro Val Gln Pro Leu
                  95                 100                 105

 Ala Glu Lys Gln Thr Lys Ser Ile Ser Ser Pro Val Ser Lys Arg
                 110                 115                 120

 Lys Pro Ala Met Ser Pro Leu Leu Thr Arg Pro Ser Tyr Ile Arg
                 125                 130                 135

 Ser Leu Arg Lys Ala Glu Lys Arg Gly Ala Lys Thr Pro Ser Thr
                 140                 145                 150

 Asn Val Lys Pro Lys Thr Pro His Gln Arg Lys Gly Gly Pro Gln
                 155                 160                 165

 Ser Gln Leu Cys Asp Lys Ala Ala Asn Leu Ile Glu Glu Leu Thr
                 170                 175                 180

 Ser Ile Phe Lys Ala Ala Lys Pro Arg Asn Arg Ser Pro Asn Gly
                 185                 190                 195

 Glu Ser Ser Ser Pro Asp Ser Gly Tyr Leu Ser Pro Lys Asn Gln
                 200                 205                 210

 Pro Ser Ala Leu Leu Ser Ala Ser Ala Ser Gln Ser Pro Met Glu
                 215                 220                 225

 Asp Gln Gly Glu Met Glu Arg Glu Val Lys Ser Pro Gly Ala Arg
                 230                 235                 240

 His Cys Tyr Gln Asp Asn Gln Asp Leu Ala Val Pro His Asn Arg
                 245                 250                 255

 Lys Ser His Pro Gln Pro His Ser Ala Leu His Phe Pro Ala Ala
                 260                 265                 270

 Pro Arg Phe Ile Gln Lys Leu Arg Ser Gln Glu Val Ala Glu Gly
                 275                 280                 285

 Ser Arg Val Tyr Leu Glu Cys Arg Val Thr Gly Asn Pro Thr Pro
                 290                 295                 300

 Arg Val Arg Trp Phe Cys Glu Gly Lys Glu Leu His Asn Thr Pro
                 305                 310                 315

 Asp Ile Gln Ile His Cys Glu Gly Gly Asp Leu His Thr Leu Ile
                 320                 325                 330

 Ile Ala Glu Ala Phe Glu Asp Asp Thr Gly Arg Tyr Thr Cys Leu
                 335                 340                 345

 Ala Thr Asn Pro Ser Gly Ser Asp Thr Thr Ser Ala Glu Val Phe
                 350                 355                 360

 Ile Glu Gly Ala Ser Ser Thr Asp Ser Asp Ser Glu Ser Leu Ala
                 365                 370                 375

 Phe Lys Ser Arg Ala Gly Ala Met Pro Gln Ala Gln Lys Lys Thr
                 380                 385                 390

 Thr Ser Val Ser Leu Thr Ile Gly Ser Ser Ser Pro Lys Thr Gly
                 395                 400                 405

 Val Thr Thr Ala Val Ile Gln Pro Leu Ser Val Pro Val Gln Gln
                 410                 415                 420

 Val His Ser Pro Thr Ser Tyr Leu Cys Arg Pro Asp Gly Thr Thr
                 425                 430                 435

 Thr Ala Tyr Phe Pro Pro Val Phe Thr Lys Glu Leu Gln Asn Thr
                 440                 445                 450

 Ala Val Ala Glu Gly Gln Val Val Val Leu Glu Cys Arg Val Arg
                 455                 460                 465

 Gly Ala Pro Pro Leu Gln Val Gln Trp Phe Arg Gln Gly Ser Glu
                 470                 475                 480

 Ile Gln Asp Ser Pro Asp Phe Arg Ile Leu Gln Lys Lys Pro Arg
                 485                 490                 495

 Ser Thr Ala Glu Pro Glu Glu Ile Cys Thr Leu Val Ile Ala Glu
                 500                 505                 510

 Thr Phe Pro Glu Asp Ala Gly Ile Phe Thr Cys Ser Ala Arg Asn
                 515                 520                 525

 Asp Tyr Gly Ser Ala Thr Ser Thr Ala Gln Leu Val Val Thr Ser
                 530                 535                 540

 Ala Asn Thr Glu Asn Cys Ser Tyr Glu Ser Met Gly Glu Ser Asn
                 545                 550                 555

 Asn Asp His Phe Gln His Phe Pro Pro Pro Pro Pro Ile Leu Glu
                 560                 565                 570

 Thr Ser Ser Leu Glu Leu Ala Ser Lys Lys Pro Ser Glu Ile Gln
                 575                 580                 585

 Gln Val Asn Asn Pro Glu Leu Gly Leu Ser Arg Ala Ala Leu Gln
                 590                 595                 600

 Met Gln Phe Asn Ala Ala Glu Arg Glu Thr Ser Gly Val His Pro
                 605                 610                 615

 Ser Arg Gly Val Asn Gly Leu Ile Asn Gly Lys Ala Asn Ser Asn
                 620                 625                 630

 Lys Ser Leu Pro Thr Pro Ala Val Leu Leu Ser Pro Thr Lys Glu
                 635                 640                 645

 Pro Pro Pro Leu Leu Ala Lys Pro Lys Leu Gly Phe Pro Lys Lys
                 650                 655                 660

 Ala Ser Arg Thr Ala Arg Ile Ala Ser Asp Glu Glu Ile Gln Gly
                 665                 670                 675

 Thr Lys Asp Ala Val Ile Gln Asp Leu Glu Arg Lys Leu Arg Phe
                 680                 685                 690

 Lys Glu Asp Leu Leu Asn Asn Gly Gln Pro Arg Leu Thr Tyr Glu
                 695                 700                 705

 Glu Arg Met Ala Arg Arg Leu Leu Gly Ala Asp Ser Ala Thr Val
                 710                 715                 720

 Phe Asn Ile Gln Glu Pro Glu Glu Glu Thr Ala Asn Gln Glu Tyr
                 725                 730                 735

 Lys Val Ser Ser Cys Glu Gln Arg Leu Ile Ser Glu Ile Glu Tyr
                 740                 745                 750

 Arg Leu Glu Arg Ser Pro Val Asp Glu Ser Gly Asp Glu Val Gln
                 755                 760                 765

 Tyr Gly Asp Val Pro Val Glu Asn Gly Met Ala Pro Phe Phe Glu
                 770                 775                 780

 Met Lys Leu Lys His Tyr Lys Ile Phe Glu Gly Met Pro Val Thr
                 785                 790                 795

 Phe Thr Cys Arg Val Ala Gly Asn Pro Lys Pro Lys Ile Tyr Trp
                 800                 805                 810

 Phe Lys Asp Gly Lys Gln Ile Ser Pro Lys Ser Asp His Tyr Thr
                 815                 820                 825

 Ile Gln Arg Asp Leu Asp Gly Thr Cys Ser Leu His Thr Thr Ala
                 830                 835                 840

 Ser Thr Leu Asp Asp Asp Gly Asn Tyr Thr Ile Met Ala Ala Asn
                 845                 850                 855

 Pro Gln Gly Arg Ile Ser Cys Thr Gly Arg Leu Met Val Gln Ala
                 860                 865                 870

 Val Asn Gln Arg Gly Arg Ser Pro Arg Ser Pro Ser Gly His Pro
                 875                 880                 885

 His Val Arg Arg Pro Arg Ser Arg Ser Arg Asp Ser Gly Asp Glu
                 890                 895                 900

 Asn Glu Pro Ile Gln Glu Arg Phe Phe Arg Pro His Phe Leu Gln
                 905                 910                 915

 Ala Pro Gly Asp Leu Thr Val Gln Glu Gly Lys Leu Cys Arg Met
                 920                 925                 930

 Asp Cys Lys Val Ser Gly Leu Pro Thr Pro Asp Leu Ser Trp Gln
                 935                 940                 945

 Leu Asp Gly Lys Pro Val Arg Pro Asp Ser Ala His Lys Met Leu
                 950                 955                 960

 Val Arg Glu Asn Gly Val His Ser Leu Ile Ile Glu Pro Val Thr
                 965                 970                 975

 Ser Arg Asp Ala Gly Ile Tyr Thr Cys Ile Ala Thr Asn Arg Ala
                 980                 985                 990

 Gly Gln Asn Ser Phe Ser Leu Glu Leu Val Val Ala Ala Lys Glu
                 995                1000                1005

 Ala His Lys Pro Pro Val Phe Ile Glu Lys Leu Gln Asn Thr Gly
                1010                1015                1020

 Val Ala Asp Gly Tyr Pro Val Arg Leu Glu Cys Arg Val Leu Gly
                1025                1030                1035

 Val Pro Pro Pro Gln Ile Phe Trp Lys Lys Glu Asn Glu Ser Leu
                1040                1045                1050

 Thr His Ser Thr Asp Arg Val Ser Met His Gln Asp Asn His Gly
                1055                1060                1065

 Tyr Ile Cys Leu Leu Ile Gln Gly Ala Thr Lys Glu Asp Ala Gly
                1070                1075                1080

 Trp Tyr Thr Val Ser Ala Lys Asn Glu Ala Gly Ile Val Ser Cys
                1085                1090                1095

 Thr Ala Arg Leu Asp Val Tyr Ile Ser Arg His
                1100                1105

<210> 136
<211> 482
<212> DNA
<213> Homo sapien

<400> 136
 ttccttttcc tccctgtcgc caccgaggtc gcacgcgtga gacttctccg 50

 ccgcctccgc cgcagacgcc gccgcgatgc gctacgtcgc ctcctacctg 100

 ctggctgccc tagggggcaa ctcctccccc agcgccaagg acatcaagaa 150

 gatcttggac agcgtgggta tcgaggcgga cgacgaccgg ctcaacaagg 200

 ttatcagtga gctgaatgga aaaaacattg aagacgtcat tgcccagggt 250

 attggcaagc ttgccagtgt acctgctggt ggggctgtag ccgtctctgc 300

 tgccccaggc tctgcagccc ctgctgctgg ttctgcccct gctgcagcag 350

 aggagaagaa agatgagaag aaggaggagt ctgaagagtc agatgatgac 400

 atgggatttg gcctttttga ttaaattcct gctcccctgc aaataaagcc 450

 tttttacaca tctcaaaaaa aaaaaaaaaa aa 482

<210> 137
<211> 115
<212> PRT
<213> Homo sapien

<400> 137
 Met Arg Tyr Val Ala Ser Tyr Leu Leu Ala Ala Leu Gly Gly Asn
   1               5                  10                  15

 Ser Ser Pro Ser Ala Lys Asp Ile Lys Lys Ile Leu Asp Ser Val
                  20                  25                  30

 Gly Ile Glu Ala Asp Asp Asp Arg Leu Asn Lys Val Ile Ser Glu
                  35                  40                  45

 Leu Asn Gly Lys Asn Ile Glu Asp Val Ile Ala Gln Gly Ile Gly
                  50                  55                  60

 Lys Leu Ala Ser Val Pro Ala Gly Gly Ala Val Ala Val Ser Ala
                  65                  70                  75

 Ala Pro Gly Ser Ala Ala Pro Ala Ala Gly Ser Ala Pro Ala Ala
                  80                  85                  90

 Ala Glu Glu Lys Lys Asp Glu Lys Lys Glu Glu Ser Glu Glu Ser
                  95                 100                 105

 Asp Asp Asp Met Gly Phe Gly Leu Phe Asp
                 110                 115

<210> 138
<211> 1901
<212> DNA
<213> Homo sapien

<400> 138
 atggggcatc ggccggtgct cgtgctcagc cagaacacaa agcgtgaatc 50

 cggaagaaaa gttcaatctg gaaacatcaa tgctgccaag actattgcag 100

 atatcatccg aacatgtttg ggacccaagt ccatgatgaa gatgcttttg 150

 gacccaatgg gaggcattgt gatgaccaat gatggcaatg ccattcttcg 200

 agagattcaa gtccagcatc cagcggccaa gtccatgatc gaaattagcc 250

 ggacccagga tgaagaagtt ggagatggga ccacatcagt aattattctt 300

 gcaggggaaa tgctgtctgt agctgagcac ttcctggagc agcagatgca 350

 cccaacagtg gtgatcagtg cttaccgcaa ggcattggat gatatgatca 400

 gcaccctaaa gaaaataagt atcccagtcg acatcagtga cagtgatatg 450

 atgctgaaca tcatcaacag ctctattact accaaagcca tcagccggtg 500

 gtcatctttg gcttgcaaca ttgccctgga tgctgtcaag atggtacagt 550

 ttgaggagaa tggtcggaaa gagattgaca taaaaaaata tgcaagagtg 600

 gaaaagatac ctggaggcat cattgaagac tcctgtgtct tgcgtggagt 650

 catgattaac aaggatgtga cccatccacg tatgcggcgc tatatcaaga 700

 accctcgcat tgtgctgctg gattcttctc tggaatacaa gaaaggagga 750

 agccagactg acattgagat tacacgagag gaggacttca cccgaattct 800

 ccagatggag gaagagtaca tccagcagct ctgtgaggac attatccaac 850

 tgaagcccga tgtggtcatc actgaaaagg gcatctcaga tttagctcag 900

 cactacctta tgcgggccaa tatcacagcc atccgcagag tccggaagac 950

 agacaataat cgcattgcta gagcctgtgg ggcccggata gtcagccgac 1000

 cagaggaact gagagaagat gatgttggaa caggagcagg cctgttggaa 1050

 atcaagaaaa ttggagatga atactttact ttcatcactg actgcaaaga 1100

 ccccaaggcc tgcaccattc tcctccgggg ggctagcaaa gagattctct 1150

 cggaagtaga acgcaacctc caggatgcca tgcaagtgtg tcgcaatgtt 1200

 ctcctggacc ctcagctggt gccagggggt ggggcctccg agatggctgt 1250

 cgcccatgcc ttgacagaaa aatccaaggc catgactggt gtggaacaat 1300

 ggccatacag ggctgttgcc caggccctag aggtcattcc tcgtaccctg 1350

 atccagaact gtggggccag caccatccgt ctacttacct cccttcgggc 1400

 caagcacacc caggagaact gtgagacctg gggtgtaaat ggtgagacgg 1450

 gtactttggt ggacatgaag gaactgggca tatgggagcc attggctgtg 1500

 aagctgcaga cttataagac agcagtggag acggcagttc tgctactgcg 1550

 aattgatgac atcgtttcag gccacaaaaa gaaaggcgat gaccagagcc 1600

 ggcaaggcgg ggctcctgat gctggccagg agtgagtgct aggcaaggct 1650

 acttcaatgc acagaaccag cagagtctcc ccttttcctg agccagagtg 1700

 ccaggaacac tgtggacgtc tttgttcaga agggatcagg ttggggggca 1750

 gcccccagtc cctttctgtc ccagctcagt tttccaaaag acactgacat 1800

 gtaattcttc tctattgtaa ggtttccatt tagtttgctt ccgatgatta 1850

 aatctaagtc atttgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1900

 a 1901

<210> 139
<211> 544
<212> PRT
<213> Homo sapien

<400> 139
 Met Gly His Arg Pro Val Leu Val Leu Ser Gln Asn Thr Lys Arg
   1               5                  10                  15

 Glu Ser Gly Arg Lys Val Gln Ser Gly Asn Ile Asn Ala Ala Lys
                  20                  25                  30

 Thr Ile Ala Asp Ile Ile Arg Thr Cys Leu Gly Pro Lys Ser Met
                  35                  40                  45

 Met Lys Met Leu Leu Asp Pro Met Gly Gly Ile Val Met Thr Asn
                  50                  55                  60

 Asp Gly Asn Ala Ile Leu Arg Glu Ile Gln Val Gln His Pro Ala
                  65                  70                  75

 Ala Lys Ser Met Ile Glu Ile Ser Arg Thr Gln Asp Glu Glu Val
                  80                  85                  90

 Gly Asp Gly Thr Thr Ser Val Ile Ile Leu Ala Gly Glu Met Leu
                  95                 100                 105

 Ser Val Ala Glu His Phe Leu Glu Gln Gln Met His Pro Thr Val
                 110                 115                 120

 Val Ile Ser Ala Tyr Arg Lys Ala Leu Asp Asp Met Ile Ser Thr
                 125                 130                 135

 Leu Lys Lys Ile Ser Ile Pro Val Asp Ile Ser Asp Ser Asp Met
                 140                 145                 150

 Met Leu Asn Ile Ile Asn Ser Ser Ile Thr Thr Lys Ala Ile Ser
                 155                 160                 165

 Arg Trp Ser Ser Leu Ala Cys Asn Ile Ala Leu Asp Ala Val Lys
                 170                 175                 180

 Met Val Gln Phe Glu Glu Asn Gly Arg Lys Glu Ile Asp Ile Lys
                 185                 190                 195

 Lys Tyr Ala Arg Val Glu Lys Ile Pro Gly Gly Ile Ile Glu Asp
                 200                 205                 210

 Ser Cys Val Leu Arg Gly Val Met Ile Asn Lys Asp Val Thr His
                 215                 220                 225

 Pro Arg Met Arg Arg Tyr Ile Lys Asn Pro Arg Ile Val Leu Leu
                 230                 235                 240

 Asp Ser Ser Leu Glu Tyr Lys Lys Gly Gly Ser Gln Thr Asp Ile
                 245                 250                 255

 Glu Ile Thr Arg Glu Glu Asp Phe Thr Arg Ile Leu Gln Met Glu
                 260                 265                 270

 Glu Glu Tyr Ile Gln Gln Leu Cys Glu Asp Ile Ile Gln Leu Lys
                 275                 280                 285

 Pro Asp Val Val Ile Thr Glu Lys Gly Ile Ser Asp Leu Ala Gln
                 290                 295                 300

 His Tyr Leu Met Arg Ala Asn Ile Thr Ala Ile Arg Arg Val Arg
                 305                 310                 315

 Lys Thr Asp Asn Asn Arg Ile Ala Arg Ala Cys Gly Ala Arg Ile
                 320                 325                 330

 Val Ser Arg Pro Glu Glu Leu Arg Glu Asp Asp Val Gly Thr Gly
                 335                 340                 345

 Ala Gly Leu Leu Glu Ile Lys Lys Ile Gly Asp Glu Tyr Phe Thr
                 350                 355                 360

 Phe Ile Thr Asp Cys Lys Asp Pro Lys Ala Cys Thr Ile Leu Leu
                 365                 370                 375

 Arg Gly Ala Ser Lys Glu Ile Leu Ser Glu Val Glu Arg Asn Leu
                 380                 385                 390

 Gln Asp Ala Met Gln Val Cys Arg Asn Val Leu Leu Asp Pro Gln
                 395                 400                 405

 Leu Val Pro Gly Gly Gly Ala Ser Glu Met Ala Val Ala His Ala
                 410                 415                 420

 Leu Thr Glu Lys Ser Lys Ala Met Thr Gly Val Glu Gln Trp Pro
                 425                 430                 435

 Tyr Arg Ala Val Ala Gln Ala Leu Glu Val Ile Pro Arg Thr Leu
                 440                 445                 450

 Ile Gln Asn Cys Gly Ala Ser Thr Ile Arg Leu Leu Thr Ser Leu
                 455                 460                 465

 Arg Ala Lys His Thr Gln Glu Asn Cys Glu Thr Trp Gly Val Asn
                 470                 475                 480

 Gly Glu Thr Gly Thr Leu Val Asp Met Lys Glu Leu Gly Ile Trp
                 485                 490                 495

 Glu Pro Leu Ala Val Lys Leu Gln Thr Tyr Lys Thr Ala Val Glu
                 500                 505                 510

 Thr Ala Val Leu Leu Leu Arg Ile Asp Asp Ile Val Ser Gly His
                 515                 520                 525

 Lys Lys Lys Gly Asp Asp Gln Ser Arg Gln Gly Gly Ala Pro Asp
                 530                 535                 540

 Ala Gly Gln Glu


<210> 140
<211> 1783
<212> DNA
<213> Homo sapien

<400> 140
 cctctcggag ctggaaatgc agctattgag atcttcgaat gctgcggagc 50

 tggaggcgga ggcagctggg gaggtccgag cgatgtgacc aggccgccat 100

 cgctcgtctc ttcctctctc ctgccgcctc ctgtgtcgaa aataactttt 150

 ttagtctaaa gaaagaaaga caaaagtagt cgtccgcccc tcacgccctc 200

 tcttcctctc agccttccgc ccggtgagga agcccggggt ggctgctccg 250

 ccgtcggggc cgcgccgccg agccccagcg ccccgggccg cccccgcacg 300

 ccgcccccat gcatcccttc tacacccggg ccgccaccat gataggcgag 350

 atcgccgccg ccgtgtcctt catctccaag tttctccgca ccaaggggct 400

 gacgagcgag cgacagctgc agaccttcag ccagagcctg caggagctgc 450

 tggcagaaca ttataaacat cactggttcc cagaaaagcc atgcaaggga 500

 tcgggttacc gttgtattcg catcaaccat aaaatggatc ctctgattgg 550

 acaggcagca cagcggattg gactgagcag tcaggagctg ttcaggcttc 600

 tcccaagtga actcacactc tgggttgacc cctatgaagt gtcctacaga 650

 attggagagg atggctccat ctgtgtgctg tatgaagcct caccagcagg 700

 aggtagcact caaaacagca ccaacgtgca aatggtagac agccgaatca 750

 gctgtaagga ggaacttctc ttgggcagaa cgagcccttc caaaaactac 800

 aatatgatga ctgtatcagg ttaagatata gtctgtggat ggatcatctg 850

 atgatgatcc ataaatttga tttttgcttt gggtgggctc ctcttgggga 900

 tggattatgg aatttaaacc atgtcacagc tgtgaagatc tggcacaaga 950

 tagaatggta aaaaaaaaaa aaaattttaa gtgacagtgc catagtttgg 1000

 acagtacctt tcaatgatta attttaatag cctgtgagtc caagtaaatg 1050

 atcactttat ttgctaggga gggaagtcct agggtggttt cagtttctcc 1100

 cagacatacc taaattttta catcaatcct tttaaagaaa atctgtattt 1150

 caaagaatct ttctctgcag taaatctcgc aggggaattt gcactattac 1200

 acttgaaagt tgttattgtt aaccttttcg gcagctttta ataggaaagt 1250

 taaacgtttt aaacatggta gtactggaaa ttttacaaga cttttaccta 1300

 gcacttaaat atgtataaat gtacataaag acaaactagt aagcatgacc 1350

 tggggaaatg gtcagacctt gtattgtgtt tttggccttg aaagtagcaa 1400

 gtgaccagaa tctgccatgg caacaggctt taaaaaagac ccttaaaaag 1450

 acactgtctc aactgtggtg ttagcaccag ccagctctct gtacatttgc 1500

 tagcttgtag ttttctaaga ctgagtaaac ttcttatttt tagaaagtgg 1550

 aggtctggtt tgtaactttc cttgtactta attgggtaaa agtcttttcc 1600

 acaaaccacc atctattttg tgaactttgt tagtcatctt ttatttggta 1650

 aattatgaac tggtgtaaat ttgtacagtt catgtatatt gattgtggca 1700

 aagttgtaca gatttctata ttttggatga gaaatttttc ttctctctat 1750

 aataaatcgt ttcttatctt ggcattttta acc 1783

<210> 141
<211> 171
<212> PRT
<213> Homo sapien

<400> 141
 Met His Pro Phe Tyr Thr Arg Ala Ala Thr Met Ile Gly Glu Ile
   1               5                  10                  15

 Ala Ala Ala Val Ser Phe Ile Ser Lys Phe Leu Arg Thr Lys Gly
                  20                  25                  30

 Leu Thr Ser Glu Arg Gln Leu Gln Thr Phe Ser Gln Ser Leu Gln
                  35                  40                  45

 Glu Leu Leu Ala Glu His Tyr Lys His His Trp Phe Pro Glu Lys
                  50                  55                  60

 Pro Cys Lys Gly Ser Gly Tyr Arg Cys Ile Arg Ile Asn His Lys
                  65                  70                  75

 Met Asp Pro Leu Ile Gly Gln Ala Ala Gln Arg Ile Gly Leu Ser
                  80                  85                  90

 Ser Gln Glu Leu Phe Arg Leu Leu Pro Ser Glu Leu Thr Leu Trp
                  95                 100                 105

 Val Asp Pro Tyr Glu Val Ser Tyr Arg Ile Gly Glu Asp Gly Ser
                 110                 115                 120

 Ile Cys Val Leu Tyr Glu Ala Ser Pro Ala Gly Gly Ser Thr Gln
                 125                 130                 135

 Asn Ser Thr Asn Val Gln Met Val Asp Ser Arg Ile Ser Cys Lys
                 140                 145                 150

 Glu Glu Leu Leu Leu Gly Arg Thr Ser Pro Ser Lys Asn Tyr Asn
                 155                 160                 165

 Met Met Thr Val Ser Gly
                 170

<210> 142
<211> 1783
<212> DNA
<213> Homo sapien

<400> 142
 cctctcggag ctggaaatgc agctattgag atcttcgaat gctgcggagc 50

 tggaggcgga ggcagctggg gaggtccgag cgatgtgacc aggccgccat 100

 cgctcgtctc ttcctctctc ctgccgcctc ctgtgtcgaa aataactttt 150

 ttagtctaaa gaaagaaaga caaaagtagt cgtccgcccc tcacgccctc 200

 tcttcctctc agccttccgc ccggtgagga agcccggggt ggctgctccg 250

 ccgtcggggc cgcgccgccg agccccagcg ccccgggccg cccccgcacg 300

 ccgcccccat gcatcccttc tacacccggg ccgccaccat gataggcgag 350

 atcgccgccg ccgtgtcctt catctccaag tttctccgca ccaaggggct 400

 gacgagcgag cgacagctgc agaccttcag ccagagcctg caggagctgc 450

 tggcagaaca ttataaacat cactggttcc cagaaaagcc atgcaaggga 500

 tcgggttacc gttgtattcg catcaaccat aaaatggatc ctctgattgg 550

 acaggcagca cagcggattg gactgagcag tcaggagctg ttcaggcttc 600

 tcccaagtga actcacactc tgggttgacc cctatgaagt gtcctacaga 650

 attggagagg atggctccat ctgtgtgctg tatgaagcct caccagcagg 700

 aggtagcact caaaacagca ccaacgtgca aatggtagac agccgaatca 750

 gctgtaagga ggaacttctc ttgggcagaa cgagcccttc caaaaactac 800

 aatatgatga ctgtatcagg ttaagatata gtctgtggat ggatcatctg 850

 atgatgatcc ataaatttga tttttgcttt gggtgggctc ctcttgggga 900

 tggattatgg aatttaaacc atgtcacagc tgtgaagatc tggcacaaga 950

 tagaatggta aaaaaaaaaa aaaattttaa gtgacagtgc catagtttgg 1000

 acagtacctt tcaatgatta attttaatag cctgtgagtc caagtaaatg 1050

 atcactttat ttgctaggga gggaagtcct agggtggttt cagtttctcc 1100

 cagacatacc taaattttta catcaatcct tttaaagaaa atctgtattt 1150

 caaagaatct ttctctgcag taaatctcgc aggggaattt gcactattac 1200

 acttgaaagt tgttattgtt aaccttttcg gcagctttta ataggaaagt 1250

 taaacgtttt aaacatggta gtactggaaa ttttacaaga cttttaccta 1300

 gcacttaaat atgtataaat gtacataaag acaaactagt aagcatgacc 1350

 tggggaaatg gtcagacctt gtattgtgtt tttggccttg aaagtagcaa 1400

 gtgaccagaa tctgccatgg caacaggctt taaaaaagac ccttaaaaag 1450

 acactgtctc aactgtggtg ttagcaccag ccagctctct gtacatttgc 1500

 tagcttgtag ttttctaaga ctgagtaaac ttcttatttt tagaaagtgg 1550

 aggtctggtt tgtaactttc cttgtactta attgggtaaa agtcttttcc 1600

 acaaaccacc atctattttg tgaactttgt tagtcatctt ttatttggta 1650

 aattatgaac tggtgtaaat ttgtacagtt catgtatatt gattgtggca 1700

 aagttgtaca gatttctata ttttggatga gaaatttttc ttctctctat 1750

 aataaatcgt ttcttatctt ggcattttta acc 1783

<210> 143
<211> 171
<212> PRT
<213> Homo sapien

<400> 143
 Met His Pro Phe Tyr Thr Arg Ala Ala Thr Met Ile Gly Glu Ile
   1               5                  10                  15

 Ala Ala Ala Val Ser Phe Ile Ser Lys Phe Leu Arg Thr Lys Gly
                  20                  25                  30

 Leu Thr Ser Glu Arg Gln Leu Gln Thr Phe Ser Gln Ser Leu Gln
                  35                  40                  45

 Glu Leu Leu Ala Glu His Tyr Lys His His Trp Phe Pro Glu Lys
                  50                  55                  60

 Pro Cys Lys Gly Ser Gly Tyr Arg Cys Ile Arg Ile Asn His Lys
                  65                  70                  75

 Met Asp Pro Leu Ile Gly Gln Ala Ala Gln Arg Ile Gly Leu Ser
                  80                  85                  90

 Ser Gln Glu Leu Phe Arg Leu Leu Pro Ser Glu Leu Thr Leu Trp
                  95                 100                 105

 Val Asp Pro Tyr Glu Val Ser Tyr Arg Ile Gly Glu Asp Gly Ser
                 110                 115                 120

 Ile Cys Val Leu Tyr Glu Ala Ser Pro Ala Gly Gly Ser Thr Gln
                 125                 130                 135

 Asn Ser Thr Asn Val Gln Met Val Asp Ser Arg Ile Ser Cys Lys
                 140                 145                 150

 Glu Glu Leu Leu Leu Gly Arg Thr Ser Pro Ser Lys Asn Tyr Asn
                 155                 160                 165

 Met Met Thr Val Ser Gly
                 170

<210> 144
<211> 5341
<212> DNA
<213> Homo sapien

<400> 144
 gcacagtctg tctcttcgcc ggttcccggc cccgtggatc ctacttctct 50

 gtcgcccgcg gttcgccgcc ccgctcgccg ccgcgatgcc agtgtttcat 100

 acgcgcacga tcgagagcat cctggagccg gtggcacagc agatctccca 150

 cctggtgata atgcacgagg agggcgaggt ggacggcaaa gccattcctg 200

 acctcaccgc gcccgtggcc gccgtgcagg cggccgtcag caacctcgtc 250

 cgggttggaa aagagactgt tcaaaccact gaggatcaga ttttgaagag 300

 agatatgcca ccagcattta ttaaggttga gaatgcttgc accaagcttg 350

 tccaggcagc tcagatgctt cagtcagacc cttactcagt gcctgctcga 400

 gattatctaa ttgatgggtc aaggggcatc ctctctggaa catcagacct 450

 gctccttacc ttcgatgagg ctgaggtccg taaaattatt agagtttgca 500

 aaggaatttt ggaatatctt acagtggcag aggtggtgga gactatggaa 550

 gatttggtca cttacacaaa gaatcttggg ccaggaatga ctaagatggc 600

 caagatgatt gacgagagac agcaggagct cactcaccag gagcaccgag 650

 tgatgttggt gaactcgatg aacaccgtga aagagttgct gccagttctc 700

 atttcagcta tgaagatttt tgtaacaact aaaaactcaa aaaaccaagg 750

 catagaggaa gctttaaaaa atcgcaattt tactgtagaa aaaatgagtg 800

 ctgaaattaa tgagataatt cgtgtgttac aactcacctc ttgggatgaa 850

 gatgcctggg ccagcaagga cactgaagcc atgaagagag cattggcctc 900

 catagactcc aaactgaacc aggccaaagg ttggctccgt gaccctagtg 950

 cctccccagg ggatgctggt gagcaggcca tcagacagat cttagatgaa 1000

 gctggaaaag ttggtgaact ctgtgcaggc aaagaacgca gggagattct 1050

 gggaacttgc aaaatgctag ggcagatgac tgatcaagtg gctgacctcc 1100

 gtgccagagg acaaggatcc tcaccggtgg ccatgcagaa agctcagcag 1150

 gtatctcagg gtctggatgt gctcacagca aaagtggaaa atgcagctcg 1200

 caagctggaa gccatgacca actcaaagca gagcattgca aagaagatcg 1250

 atgctgctca gaactggctt gcagatccaa atggtggacc ggaaggagaa 1300

 gagcagattc gaggtgcttt ggctgaagct cggaaaatag cagaattatg 1350

 tgatgatcct aaagaaagag atgacattct acgttccctt ggggaaatat 1400

 ctgctctgac ttctaaatta gcagatctac gaagacaggg gaaaggagat 1450

 tctccagagg ctcgagcctt ggccaaacag gtggccacgg ccctgcagaa 1500

 cctgcagacc aaaaccaacc gggctgtggc caacagcaga ccggccaaag 1550

 cagctgtaca ccttgagggc aagattgagc aagcacagcg gtggattgat 1600

 aatcccacag tggatgaccg tggagtcggt caggctgcca tccgggggct 1650

 tgtggccgaa gggcatcgtc tggctaatgt tatgatgggg ccttatcggc 1700

 aagatcttct cgccaagtgt gaccgagtgg accagctgac agcccagctg 1750

 gctgacctgg ctgccagagg ggaaggggag agtcctcagg cacgagcact 1800

 tgcatctcag ctccaagact ccttaaagga tctaaaagct cggatgcagg 1850

 aggccatgac tcaggaagtg tcagatgttt tcagcgatac cacaactccc 1900

 atcaagctgt tggcagtggc agccacggcg cctcctgatg cgcctaacag 1950

 ggaagaggta tttgatgaga gggcagctaa ctttgaaaac cattcaggaa 2000

 agcttggtgc tacggccgag aaggcggctg cggttggtac tgctaataaa 2050

 tcaacagtgg aaggcattca ggcctcagtg aagacggccc gagaactcac 2100

 accccaggtg gtctcggctg ctcgtatctt acttaggaac cctggaaatc 2150

 aagctgctta tgaacatttt gagaccatga agaaccagtg gatcgataat 2200

 gttgaaaaaa tgacagggct ggtggacgaa gccattgata ccaaatctct 2250

 gttggatgct tcagaagaag caattaaaaa agacctggac aagtgcaagg 2300

 tagctatggc caacattcag cctcagatgc tggttgctgg ggcaaccagt 2350

 attgctcgtc gggccaaccg gatcctgctg gtggctaaga gggaggtgga 2400

 gaattccgag gatcccaagt tccgtgaggc tgtgaaagct gcctctgatg 2450

 aattgagcaa aaccatctcc ccaatggtga tggatgcaaa agctgtggct 2500

 ggaaacattt ccgaccctgg actgcaaaag agcttcctgg actcaggata 2550

 tcggatcctg ggagctgtgg ccaaggtcag agaagccttc caacctcagg 2600

 agcctgactt cccgccgcct ccaccagacc ttgaacaact ccgactaaca 2650

 gatgagcttg ctcctcccaa accacctctg cctgaaggtg aggtccctcc 2700

 acctaggcct ccaccaccag aggaaaagga tgaagagttc cctgagcaga 2750

 aggccgggga ggtgattaac cagccaatga tgatggctgc cagacagctc 2800

 catgatgaag ctcgcaaatg gtccagcaag ccgggcatcc cagccgctga 2850

 ggtgggtata ggtgttgtag ctgaggcaga tgcggccgat gctgctggct 2900

 tccctgtccc ccctgacatg gaagacgatt acgaacctga gctgctgtta 2950

 atgccatcca atcagccggt caaccagccc attctggccg cggctcagtc 3000

 cttgcatcgg gaagctacca agtggtctag taagggcaat gacatcattg 3050

 cagcagccaa gcgcatggct ctgctgatgg ctgagatgtc tcggctggta 3100

 agagggggca gtggtaccaa gcgggcactc attcagtgtg ccaaggacat 3150

 cgccaaggcc tcagatgagg tgactcggtt ggccaaggag gttgccaagc 3200

 agtgcacaga taaacggatt agaaccaacc tcttacaggt atgtgagcga 3250

 atcccaacca taagcaccca gctcaaaatc ctgtccacag tgaaggccac 3300

 catgctgggc cggaccaaca tcagtgatga ggagtctgag caggccacag 3350

 agatgctggt tcacaatgcc cagaacctca tgcagtctgt gaaggagact 3400

 gtgcgggaag ctgaagctgc ttcaatcaaa attcgaacag atgctggatt 3450

 tacactgcgc tgggttagaa agactccctg gtaccagtag gcacctggct 3500

 gagcctggct ggcacagaaa cctctactaa aaagaaggaa aatgatctga 3550

 gtcccaggag ctgcccagag ttgctgggag ctgaaaaatc acatcctggc 3600

 ctggcacatc agaaaggaat gggggcctct tcaaattaga agacatttat 3650

 actctttttt catggacact ttgaaatgtg tttctgtata aagcctgtat 3700

 tctcaaacac agttacactt gtgcaccctc tatcccaata ggcagactgg 3750

 gtttctagcc catggacttc acataagctc agaatccaag tgaacactag 3800

 ccagacactc tgctctgccc ttgttcccta ggggacactt ccctctgttt 3850

 ctctttcctt ggctcccatt cactcttcca gaatcccaag acccagggcc 3900

 caggcaaatc agttactaag aagaaaattg ctgtgcctcc caaaattgtt 3950

 ttgagctttc catgttgctg ccaaccatac cttccttccc tgggctgtgc 4000

 tacctgggtc cttttcagaa gtgagctttg ctgctacagg ggaaggtggc 4050

 ctctgtggag ccccagcata tgggggcctg gattcatttc ctgcccttcc 4100

 tcagtttaat ccttctagtt tcccacaata taaaactgta cttcactgtc 4150

 aggaagaaat cacagaatca tatgattctg cttttaccat gcccctgagc 4200

 aatgtctgtg ctagggaaac tccccgtccc atatcctgcc tcagcccgcc 4250

 aaggtagcca tcccatgaac acactgtgtc ctggtgctct ctgccactgg 4300

 aagggcagag tagccagggt gtggccctgc catcttccca gcagggccac 4350

 tcccggcact ccatgcttag tcactgcctg cagaggtctg tgctgaggcc 4400

 ttatcattca ttcttagctc ttaattgttc attttgagct gaaatgctgc 4450

 attttaattt taaccaaaac atgtctccta tatcctggtt tttgtagcct 4500

 tcctccacat cctttctaaa caagatttta aagacatgta ggtgtttgtt 4550

 catctgtaac tctaaaagat cctttttaaa ttcagtccta agaaagagga 4600

 gtgcttgtcc cctaagagtg tttaatggca aggcagccct gtctgaagga 4650

 cacttcctgc ctaagggaga gtggtatttg cagactagaa ttctagtgct 4700

 gctgaagatg aatcaatggg aaatactact cctgtaattc ctacctccct 4750

 gcaaccaact acaaccaagc tctctgcatc tactcccaag tatggggttc 4800

 aagagagtaa tgggtttcat atttcttatc accacagtaa gttcctacta 4850

 ggcaaaatga gagggcagtg tttccttttt ggtacttatt actgctaagt 4900

 atttcccagc acatgaaacc ttattttttc caaagccaga accagatgag 4950

 taaaggagta agaaccttgc ctgaacatcc ttccttccca cccatcgctg 5000

 tgtgttagtt cccaacatcg aatgtgtaca acttaagttg gtcctttaca 5050

 ctcaggcttt cactatttcc tttaaaatga ggatgattat tttcaaggcc 5100

 ctcagcatat ttgtatagtt gcttgcctga tataaatgca atattaatgc 5150

 ctttaaagta tgaatctatg ccaaagatca cttgttgttt tactaaagaa 5200

 agattactta gaggaaataa gaaaaatcat gtttgctctc ccggttcttc 5250

 cagtggtttg agacactggt ttacacttta tgccggatgt gcttttctcc 5300

 aatatcagtg ctcgagacac agtgaagcaa attaaaaaaa a 5341

<210> 145
<211> 1134
<212> PRT
<213> Homo sapien

<400> 145
 Met Pro Val Phe His Thr Arg Thr Ile Glu Ser Ile Leu Glu Pro
   1               5                  10                  15

 Val Ala Gln Gln Ile Ser His Leu Val Ile Met His Glu Glu Gly
                  20                  25                  30

 Glu Val Asp Gly Lys Ala Ile Pro Asp Leu Thr Ala Pro Val Ala
                  35                  40                  45

 Ala Val Gln Ala Ala Val Ser Asn Leu Val Arg Val Gly Lys Glu
                  50                  55                  60

 Thr Val Gln Thr Thr Glu Asp Gln Ile Leu Lys Arg Asp Met Pro
                  65                  70                  75

 Pro Ala Phe Ile Lys Val Glu Asn Ala Cys Thr Lys Leu Val Gln
                  80                  85                  90

 Ala Ala Gln Met Leu Gln Ser Asp Pro Tyr Ser Val Pro Ala Arg
                  95                 100                 105

 Asp Tyr Leu Ile Asp Gly Ser Arg Gly Ile Leu Ser Gly Thr Ser
                 110                 115                 120

 Asp Leu Leu Leu Thr Phe Asp Glu Ala Glu Val Arg Lys Ile Ile
                 125                 130                 135

 Arg Val Cys Lys Gly Ile Leu Glu Tyr Leu Thr Val Ala Glu Val
                 140                 145                 150

 Val Glu Thr Met Glu Asp Leu Val Thr Tyr Thr Lys Asn Leu Gly
                 155                 160                 165

 Pro Gly Met Thr Lys Met Ala Lys Met Ile Asp Glu Arg Gln Gln
                 170                 175                 180

 Glu Leu Thr His Gln Glu His Arg Val Met Leu Val Asn Ser Met
                 185                 190                 195

 Asn Thr Val Lys Glu Leu Leu Pro Val Leu Ile Ser Ala Met Lys
                 200                 205                 210

 Ile Phe Val Thr Thr Lys Asn Ser Lys Asn Gln Gly Ile Glu Glu
                 215                 220                 225

 Ala Leu Lys Asn Arg Asn Phe Thr Val Glu Lys Met Ser Ala Glu
                 230                 235                 240

 Ile Asn Glu Ile Ile Arg Val Leu Gln Leu Thr Ser Trp Asp Glu
                 245                 250                 255

 Asp Ala Trp Ala Ser Lys Asp Thr Glu Ala Met Lys Arg Ala Leu
                 260                 265                 270

 Ala Ser Ile Asp Ser Lys Leu Asn Gln Ala Lys Gly Trp Leu Arg
                 275                 280                 285

 Asp Pro Ser Ala Ser Pro Gly Asp Ala Gly Glu Gln Ala Ile Arg
                 290                 295                 300

 Gln Ile Leu Asp Glu Ala Gly Lys Val Gly Glu Leu Cys Ala Gly
                 305                 310                 315

 Lys Glu Arg Arg Glu Ile Leu Gly Thr Cys Lys Met Leu Gly Gln
                 320                 325                 330

 Met Thr Asp Gln Val Ala Asp Leu Arg Ala Arg Gly Gln Gly Ser
                 335                 340                 345

 Ser Pro Val Ala Met Gln Lys Ala Gln Gln Val Ser Gln Gly Leu
                 350                 355                 360

 Asp Val Leu Thr Ala Lys Val Glu Asn Ala Ala Arg Lys Leu Glu
                 365                 370                 375

 Ala Met Thr Asn Ser Lys Gln Ser Ile Ala Lys Lys Ile Asp Ala
                 380                 385                 390

 Ala Gln Asn Trp Leu Ala Asp Pro Asn Gly Gly Pro Glu Gly Glu
                 395                 400                 405

 Glu Gln Ile Arg Gly Ala Leu Ala Glu Ala Arg Lys Ile Ala Glu
                 410                 415                 420

 Leu Cys Asp Asp Pro Lys Glu Arg Asp Asp Ile Leu Arg Ser Leu
                 425                 430                 435

 Gly Glu Ile Ser Ala Leu Thr Ser Lys Leu Ala Asp Leu Arg Arg
                 440                 445                 450

 Gln Gly Lys Gly Asp Ser Pro Glu Ala Arg Ala Leu Ala Lys Gln
                 455                 460                 465

 Val Ala Thr Ala Leu Gln Asn Leu Gln Thr Lys Thr Asn Arg Ala
                 470                 475                 480

 Val Ala Asn Ser Arg Pro Ala Lys Ala Ala Val His Leu Glu Gly
                 485                 490                 495

 Lys Ile Glu Gln Ala Gln Arg Trp Ile Asp Asn Pro Thr Val Asp
                 500                 505                 510

 Asp Arg Gly Val Gly Gln Ala Ala Ile Arg Gly Leu Val Ala Glu
                 515                 520                 525

 Gly His Arg Leu Ala Asn Val Met Met Gly Pro Tyr Arg Gln Asp
                 530                 535                 540

 Leu Leu Ala Lys Cys Asp Arg Val Asp Gln Leu Thr Ala Gln Leu
                 545                 550                 555

 Ala Asp Leu Ala Ala Arg Gly Glu Gly Glu Ser Pro Gln Ala Arg
                 560                 565                 570

 Ala Leu Ala Ser Gln Leu Gln Asp Ser Leu Lys Asp Leu Lys Ala
                 575                 580                 585

 Arg Met Gln Glu Ala Met Thr Gln Glu Val Ser Asp Val Phe Ser
                 590                 595                 600

 Asp Thr Thr Thr Pro Ile Lys Leu Leu Ala Val Ala Ala Thr Ala
                 605                 610                 615

 Pro Pro Asp Ala Pro Asn Arg Glu Glu Val Phe Asp Glu Arg Ala
                 620                 625                 630

 Ala Asn Phe Glu Asn His Ser Gly Lys Leu Gly Ala Thr Ala Glu
                 635                 640                 645

 Lys Ala Ala Ala Val Gly Thr Ala Asn Lys Ser Thr Val Glu Gly
                 650                 655                 660

 Ile Gln Ala Ser Val Lys Thr Ala Arg Glu Leu Thr Pro Gln Val
                 665                 670                 675

 Val Ser Ala Ala Arg Ile Leu Leu Arg Asn Pro Gly Asn Gln Ala
                 680                 685                 690

 Ala Tyr Glu His Phe Glu Thr Met Lys Asn Gln Trp Ile Asp Asn
                 695                 700                 705

 Val Glu Lys Met Thr Gly Leu Val Asp Glu Ala Ile Asp Thr Lys
                 710                 715                 720

 Ser Leu Leu Asp Ala Ser Glu Glu Ala Ile Lys Lys Asp Leu Asp
                 725                 730                 735

 Lys Cys Lys Val Ala Met Ala Asn Ile Gln Pro Gln Met Leu Val
                 740                 745                 750

 Ala Gly Ala Thr Ser Ile Ala Arg Arg Ala Asn Arg Ile Leu Leu
                 755                 760                 765

 Val Ala Lys Arg Glu Val Glu Asn Ser Glu Asp Pro Lys Phe Arg
                 770                 775                 780

 Glu Ala Val Lys Ala Ala Ser Asp Glu Leu Ser Lys Thr Ile Ser
                 785                 790                 795

 Pro Met Val Met Asp Ala Lys Ala Val Ala Gly Asn Ile Ser Asp
                 800                 805                 810

 Pro Gly Leu Gln Lys Ser Phe Leu Asp Ser Gly Tyr Arg Ile Leu
                 815                 820                 825

 Gly Ala Val Ala Lys Val Arg Glu Ala Phe Gln Pro Gln Glu Pro
                 830                 835                 840

 Asp Phe Pro Pro Pro Pro Pro Asp Leu Glu Gln Leu Arg Leu Thr
                 845                 850                 855

 Asp Glu Leu Ala Pro Pro Lys Pro Pro Leu Pro Glu Gly Glu Val
                 860                 865                 870

 Pro Pro Pro Arg Pro Pro Pro Pro Glu Glu Lys Asp Glu Glu Phe
                 875                 880                 885

 Pro Glu Gln Lys Ala Gly Glu Val Ile Asn Gln Pro Met Met Met
                 890                 895                 900

 Ala Ala Arg Gln Leu His Asp Glu Ala Arg Lys Trp Ser Ser Lys
                 905                 910                 915

 Pro Gly Ile Pro Ala Ala Glu Val Gly Ile Gly Val Val Ala Glu
                 920                 925                 930

 Ala Asp Ala Ala Asp Ala Ala Gly Phe Pro Val Pro Pro Asp Met
                 935                 940                 945

 Glu Asp Asp Tyr Glu Pro Glu Leu Leu Leu Met Pro Ser Asn Gln
                 950                 955                 960

 Pro Val Asn Gln Pro Ile Leu Ala Ala Ala Gln Ser Leu His Arg
                 965                 970                 975

 Glu Ala Thr Lys Trp Ser Ser Lys Gly Asn Asp Ile Ile Ala Ala
                 980                 985                 990

 Ala Lys Arg Met Ala Leu Leu Met Ala Glu Met Ser Arg Leu Val
                 995                1000                1005

 Arg Gly Gly Ser Gly Thr Lys Arg Ala Leu Ile Gln Cys Ala Lys
                1010                1015                1020

 Asp Ile Ala Lys Ala Ser Asp Glu Val Thr Arg Leu Ala Lys Glu
                1025                1030                1035

 Val Ala Lys Gln Cys Thr Asp Lys Arg Ile Arg Thr Asn Leu Leu
                1040                1045                1050

 Gln Val Cys Glu Arg Ile Pro Thr Ile Ser Thr Gln Leu Lys Ile
                1055                1060                1065

 Leu Ser Thr Val Lys Ala Thr Met Leu Gly Arg Thr Asn Ile Ser
                1070                1075                1080

 Asp Glu Glu Ser Glu Gln Ala Thr Glu Met Leu Val His Asn Ala
                1085                1090                1095

 Gln Asn Leu Met Gln Ser Val Lys Glu Thr Val Arg Glu Ala Glu
                1100                1105                1110

 Ala Ala Ser Ile Lys Ile Arg Thr Asp Ala Gly Phe Thr Leu Arg
                1115                1120                1125

 Trp Val Arg Lys Thr Pro Trp Tyr Gln
                1130

<210> 146
<211> 967
<212> DNA
<213> Mus musculus

<400> 146
 gcggcatggg cagtatccgc cgccatcctc ttccgtgagg cgcgctgaga 50

 cccggaccgg ccctcctgag aggatgccgg tgcgggcgcc cgcggagagg 100

 gacccgtcgc catgggccgt gtgatccgtg gacagaggaa gggcgccggg 150

 tctgtgttcc gcgcgcacgt gaagcaccgt aaaggcgctg cgcgcctgcg 200

 cgccgtggat ttcgctgagc ggcacggcta catcaagggc atcgtcaagg 250

 acatcatcca cgacccgggc cgcggcgcgc ccctcgccaa ggtggtcttc 300

 cgggatccgt atcggtttaa gaagcggacg gagctgttca ttgccgccga 350

 gggcattcac acgggccagt ttgtgtattg cggcaagaag gcccagctca 400

 acattggcaa tgtgctccct gtgggcacca tgcctgaggg tacaatcgtg 450

 tgctgcctgg aggagaagcc tggagaccgt ggcaagctgg cccgggcatc 500

 agggaactat gccaccgtta tctcccacaa ccctgagacc aagaagaccc 550

 gtgtgaagct gccctccggc tccaagaagg ttatctcctc agccaacaga 600

 gctgtggttg gtgtggtggc tggaggtggc cgaattgaca aacccatctt 650

 gaaggctggc cgggcgtacc acaaatataa ggcaaagagg aactgctggc 700

 cacgagtacg gggtgtggcc atgaatcctg tggagcatcc ttttggaggt 750

 ggcaaccacc agcacatcgg caagccctcc accatccgca gagatgcccc 800

 tgctggccgc aaagtgggtc tcattgctgc ccgccggact ggacgtctcc 850

 ggggaaccaa gactgtgcag gagaaagaga actagtgctg agggcctcaa 900

 taaagtttgt gtttatgcca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 950

 aaaaaaaaaa aaaaaaa 967

<210> 147
<211> 257
<212> PRT
<213> Mus musculus

<400> 147
 Met Gly Arg Val Ile Arg Gly Gln Arg Lys Gly Ala Gly Ser Val
   1               5                  10                  15

 Phe Arg Ala His Val Lys His Arg Lys Gly Ala Ala Arg Leu Arg
                  20                  25                  30

 Ala Val Asp Phe Ala Glu Arg His Gly Tyr Ile Lys Gly Ile Val
                  35                  40                  45

 Lys Asp Ile Ile His Asp Pro Gly Arg Gly Ala Pro Leu Ala Lys
                  50                  55                  60

 Val Val Phe Arg Asp Pro Tyr Arg Phe Lys Lys Arg Thr Glu Leu
                  65                  70                  75

 Phe Ile Ala Ala Glu Gly Ile His Thr Gly Gln Phe Val Tyr Cys
                  80                  85                  90

 Gly Lys Lys Ala Gln Leu Asn Ile Gly Asn Val Leu Pro Val Gly
                  95                 100                 105

 Thr Met Pro Glu Gly Thr Ile Val Cys Cys Leu Glu Glu Lys Pro
                 110                 115                 120

 Gly Asp Arg Gly Lys Leu Ala Arg Ala Ser Gly Asn Tyr Ala Thr
                 125                 130                 135

 Val Ile Ser His Asn Pro Glu Thr Lys Lys Thr Arg Val Lys Leu
                 140                 145                 150

 Pro Ser Gly Ser Lys Lys Val Ile Ser Ser Ala Asn Arg Ala Val
                 155                 160                 165

 Val Gly Val Val Ala Gly Gly Gly Arg Ile Asp Lys Pro Ile Leu
                 170                 175                 180

 Lys Ala Gly Arg Ala Tyr His Lys Tyr Lys Ala Lys Arg Asn Cys
                 185                 190                 195

 Trp Pro Arg Val Arg Gly Val Ala Met Asn Pro Val Glu His Pro
                 200                 205                 210

 Phe Gly Gly Gly Asn His Gln His Ile Gly Lys Pro Ser Thr Ile
                 215                 220                 225

 Arg Arg Asp Ala Pro Ala Gly Arg Lys Val Gly Leu Ile Ala Ala
                 230                 235                 240

 Arg Arg Thr Gly Arg Leu Arg Gly Thr Lys Thr Val Gln Glu Lys
                 245                 250                 255

 Glu Asn


<210> 148
<211> 547
<212> DNA
<213> Homo sapien

<400> 148
 acggaagtgt aggttacggt ctgagacatc accgccaagc tgggcatcgg 50

 ggagatggcc gagactgacc ccaagaccgt gcaggacctc acctcggtgg 100

 tgcagacact cctgcagcag atgcaagata aatttcagac catgtctgac 150

 cagatcattg ggagaattga tgatatgagt agtcgcattg atgatctgga 200

 aaagaatatc gcggacctca tgacacaggc tggggtggaa gaactggaaa 250

 gtgaaaacaa gatacctgcc acgcaaaaga gttgaaggtt gctaataatt 300

 tatactggaa tctggcattt ttccaagcca agagaagatc gaatggcttt 350

 ttgcagctaa ctactatgtg tagacaggtt ttatattata aagtatgcat 400

 tcttatcacc tagtatatag ttagtttgta gagtgatttc cccccagttt 450

 cttgaacatg gtatcttcac atcttggacc ttggtcagtt gtgctattca 500

 ttattaaaca ctaaaacttt ggcggttctt gcataaaaaa aaaaaaa 547

<210> 149
<211> 76
<212> PRT
<213> Homo sapien

<400> 149
 Met Ala Glu Thr Asp Pro Lys Thr Val Gln Asp Leu Thr Ser Val
   1               5                  10                  15

 Val Gln Thr Leu Leu Gln Gln Met Gln Asp Lys Phe Gln Thr Met
                  20                  25                  30

 Ser Asp Gln Ile Ile Gly Arg Ile Asp Asp Met Ser Ser Arg Ile
                  35                  40                  45

 Asp Asp Leu Glu Lys Asn Ile Ala Asp Leu Met Thr Gln Ala Gly
                  50                  55                  60

 Val Glu Glu Leu Glu Ser Glu Asn Lys Ile Pro Ala Thr Gln Lys
                  65                  70                  75

 Ser


<210> 150
<211> 6480
<212> DNA
<213> Homo sapien

<400> 150
 agagcgagca ggggagagcg agaccagttt taaggggagg accggtgcga 50

 gtgaggcagc cccgaggctc tgctcgccca ccacccaatc ctcgcctccc 100

 ttctgctcca ccttctctct ctgccctcac ctctcccccg aaaaccccct 150

 atttagccaa aggaaggagg tcaggggaac gctctcccct ccccttccaa 200

 aaaacaaaaa cagaaaaacc cttttccagg ccggggaaag caggagggag 250

 aggggccgcc gggctggcca tggagctgct gtgccacgag gtggacccgg 300

 tccgcagggc cgtgcgggac cgcaacctgc tccgagacga ccgcgtcctg 350

 cagaacctgc tcaccatcga ggagcgctac cttccgcagt gctcctactt 400

 caagtgcgtg cagaaggaca tccaacccta catgcgcaga atggtggcca 450

 cctggatgct ggaggtctgt gaggaacaga agtgcgaaga agaggtcttc 500

 cctctggcca tgaattacct ggaccgtttc ttggctgggg tcccgactcc 550

 gaagtcccat ctgcaactcc tgggtgctgt ctgcatgttc ctggcctcca 600

 aactcaaaga gaccagcccg ctgaccgcgg agaagctgtg catttacacc 650

 gacaactcca tcaagcctca ggagctgctg gagtgggaac tggtggtgct 700

 ggggaagttg aagtggaacc tggcagctgt cactcctcat gacttcattg 750

 agcacatctt gcgcaagctg ccccagcagc gggagaagct gtctctgatc 800

 cgcaagcatg ctcagacctt cattgctctg tgtgccaccg actttaagtt 850

 tgccatgtac ccaccgtcga tgatcgcaac tggaagtgtg ggagcagcca 900

 tctgtgggct ccagcaggat gaggaagtga gctcgctcac ttgtgatgcc 950

 ctgactgagc tgctggctaa gatcaccaac acagacgtgg attgtctcaa 1000

 agcttgccag gagcagattg aggcggtgct cctcaatagc ctgcagcagt 1050

 accgtcagga ccaacgtgac ggatccaagt cggaggatga actggaccaa 1100

 gccagcaccc ctacagacgt gcgggatatc gacctgtgag gatgccagtt 1150

 gggccgaaag agagagacgc gtccataatc tggtctcttc ttctttctgg 1200

 ttgtttttgt tctttgtgtt ttagggtgaa acttaaaaaa aaaattctgc 1250

 ccccacctag atcatattta aagatctttt agaagtgaga gaaaaaggtc 1300

 ctacgaaaac ggaataataa aaagcatttg gtgcctattt gaagtacagc 1350

 ataagggaat cccttgtata tgcgaacagt tattgtttga ttatgtaaaa 1400

 gtaatagtaa aatgcttaca ggaaaacctg cagagtagtt agagaatatg 1450

 tatgcctgca atatgggaac aaattagagg agactttttt ttttcatgtt 1500

 atgagctagc acatacaccc ccttgtagta taatttcaag gaactgtgta 1550

 cgccatttat ggcatgatta gattgcaaag caatgaactc aagaaggaat 1600

 tgaaataagg agggacatga tggggaagga gtacaaaaca atctctcaac 1650

 atgattgaac catttgggat ggagaagcac ctttgctctc agccacctgt 1700

 tactaagtca ggagtgtagt tggatctcta cattaatgtc ctcttgctgt 1750

 ctacagtagc tgctacctaa aaaaagatgt tttattttgc cagttggaca 1800

 caggtgattg gctcctgggt ttcatgttct gtgacatcct gcttcttctt 1850

 ccaaatgcag ttcattgcag acaccaccat attgctatct aatggggaaa 1900

 tgtagctatg ggccataacc aaaactcaca tgaaacggag gcagatggag 1950

 accaagggtg ggatccagaa tggagtcttt tctgttattg tatttaaaag 2000

 ggtaatgtgg ccttggcatt tcttcttaga aaaaaactaa tttttggtgc 2050

 tgattggcat gtctggttca cagtttagca ttgttataaa ccattccatt 2100

 cgaaaagcac tttgaaaaat tgttcccgag cgatagatgg gatggtttat 2150

 gcaagtcatg ctgaatactc ctcccctctt ctcttttgcc ccctcccttc 2200

 ctgcccccag tctgggttac tcttcgcttc tggtatctgg cgttctttgg 2250

 tacacagttc tggtgttcct accaggactc aagagacacc ccttcctgct 2300

 gacattccca tcacaacatt cctcagacaa gcctgtaaac taaaatctgt 2350

 taccattctg atggcacaga aggatcttaa ttcccatctc tatacttctc 2400

 ctttggacat ggaaagaaaa gttattgctg gtgcaaagat agatggctga 2450

 acatcagggt gtggcatttt gttccctttt ccgttttttt tttttttatt 2500

 gttgttgtta attttattgc aaagttgtat tcagcgtact tgaatttttc 2550

 ttcctctcca cttcttagag gcattcagtt agcaaagagg ttggagcaac 2600

 aacttttttt tttttttttg cacaattgta attgacaggt aatgaagcta 2650

 tttgttaaaa tatttgcctt tttaagtaaa aaagaaaaat cagaacaggg 2700

 ctatttgaag aattatttta tacacagatt ctgccttgtt tcatagtatg 2750

 agggttgaag acggaaaaca atctaagggt ctctcatttt tttaattttg 2800

 ttttgttcag tttggttttt tttttttttt gcgctgctaa gaagctaaag 2850

 tcatccatcc ttattcacgt tgacagtacc tagctgtaat gtttcacaga 2900

 gtgtgctgct attttataaa catttttata atatattatt ttactgctta 2950

 aattccaagt cctgaagtag atggttgaga tatgagttct tcgtactgga 3000

 aaagcccttc cgtagtttgt tttcttctgg tagcatattc atggttgttt 3050

 ttttttttct tttttggttt tttggttttt tttttttcct ctgatcacat 3100

 tcttcaaaga cggagtattc tttacctcag gtttactgga caaaatcaat 3150

 aactacaaaa ggcaatgatt cacgcttttg ttttcataat acctcacaac 3200

 cgtacagttt ctgcttggga gcccattcgc atgaggaata cagaagcagt 3250

 gtgagcaggg ctgactccct ctcaggtgga aggcagggcg gtctcactcc 3300

 cagggacctt tttggtcatg gaggccatcg ggctcccagt tagaccctgg 3350

 tatcctcatc atgatggaaa aaatacattg aaccaaggga tcctccctcc 3400

 ccttcaaggc agacgttcag tacaaacatt tatgcggtag gctcagatgt 3450

 cgtaatttgc acttaggtac caggtgtcag gaaacagact aaaaagaatt 3500

 ccaccaggct gtttggagat cctcatcttg gagctttttc aaaagcgggg 3550

 cttcatctgc aaagggccct ttcatcttga agtttttccc ctccgtcttt 3600

 cccctcccct ggcatggaca ccttgtgttt aggatcatct ctgcaggttt 3650

 cctaggtctg aatctgcgag tagatgaacc tgcagcaagc agcgtttatg 3700

 gtgcttcctt ctccctcctc tgtctcaaac tgcgcaggca agcactatgc 3750

 aagcccaggc cctctgctga gcggtactaa acggtcgggt tttcaatcac 3800

 actgaattgg caggataaga aaaataggtc agataagtat gggatgatag 3850

 ttgaagggag gtgaagaggc tgcttctcta cagaggtgaa attccagatg 3900

 agtcagtctc ttgggaagtg tgtttagaag ggttcaggac tttgtgagtt 3950

 agcatgaccc taaaattcta ggggatttct ggtgggacaa tgggtggtga 4000

 attttgaagt tttggagagg gaagtggagc agccagcaag taagctagcc 4050

 agagttttct caagagccag ctttgctcag cacactctcc tgggccccaa 4100

 ggagtcccac ggaatgggga aagtgggaac cctggagttc ttgggaatct 4150

 tggagcctaa agagaaaccg aggtgcaaat tcatttcatg gtgactgacc 4200

 cttgagctta aacagaagca gcaaatgaaa gaaccggaca aataaggaag 4250

 ggcacaagcc tacccgactc tatttacagt ctgtaacttt ccactcttcc 4300

 tgtagtcccg aggcccctgg gtccttctag cttttctctt tcccatcctt 4350

 ggggccttgt gtgatgatgg gtgtggggct gccgatggga aagtcggggg 4400

 ttgttaggct tttctgcctg ctcctgctta aacacaagaa ggaatcctgg 4450

 attttgccct ctccttagct cttagtctct ttggtaggag ttttgttcca 4500

 gaggagctct cccccttgga tttgaacttg ctctttttgt tgttgttgtt 4550

 ctttctcttc tttttcttac ctcccactaa aggggttcca aattatcctg 4600

 gtctttttct accttgttgt gtttctatct cgtctttact tccatctgtt 4650

 tgtttttttc tccatcagtg ggggccgagt tgttccccca gcctgccaaa 4700

 ttttgatcct tcccctcttt tggccaaatc ctagggggaa gaaatcctag 4750

 tatgccaaaa atatatgcta agcataatta aactccatgc gggtccataa 4800

 cagccaagaa gcctgcagga gaaagccaag ggcagttccc tccgcagaac 4850

 accccatgcg tgctgagagg cgagctcctt gaagaagggg ctgttcttcc 4900

 aggaggcctt attttgaact gcctcaggac cccactggag agcacagcat 4950

 gccttactac tgggtcatcc ttggtctatg tgctctgtac tggaggctct 5000

 gttctgcctc ttatcagcca ggtcaggggc acacatggct taagtgacaa 5050

 agccagagga gaagacaacc ctgacagcat cacgctgcat cccattgcta 5100

 gcaggattgg caactcttca gacggagctg cgcttccctg cagtctagca 5150

 cctctagggc ctctccagac tgtgccctgg gagctctggg actgaaaggt 5200

 taagaacata aggcaggatc agatgactct ctccaagagg gcaggggaat 5250

 tttctctcca tgggccacag gggacagggc tgggagaaga aatagacttg 5300

 caccttatgt catgtaaata attgattttc tagttcaaga agataatatt 5350

 ggtagtgtgg gaattggagg taggaagggg aggaagtctg agtaagccag 5400

 ttggcttcta agccaaaagg attcctcttt gtttatctct gagacagtcc 5450

 aaccttgaga atagctttaa aagggaaatt aatgctgaga tgataaagtc 5500

 cccttaagcc aacaaaccct ctgtagctat agaatgagtg caggtttcta 5550

 ttggtgtgga ctcagagcaa tttacaagag ctgttcatgc agccatccat 5600

 ttgtgcaaaa tagggtaaga agattcaaga ggatatttat tacttcctca 5650

 taccacatgg cttttgatga ttctggattc taaacaaccc agaatggtca 5700

 tttcaggcac aacgatacta cattcgtgtg tgtctgcttt taaacttggc 5750

 tgggctatca gaccctattc tcggctcagg ttttgagaag ccatcagcaa 5800

 atgtgtacgt gcatgctgta gctgcagcct gcatcccttc gcctgcagcc 5850

 tactttgggg aaataaagtg ccttactgac tgtagccatt acagtatcca 5900

 atgtcttttg acaggtgcct gtccttgaaa aacaaagttt ctatttttat 5950

 ttttaattgg tttagttctt aactgctggc caactcttac atccccagca 6000

 aatcatcggg ccattggatt ttttccatta tgttcatcac ccttatatca 6050

 tgtacctcag atctctctct ctctcctctc tctcagttat atagtttctt 6100

 gtcttggact ttttttttct tttctttttc tttttttttt tgctttaaaa 6150

 caagtgtgat gccatatcaa gtccatgtta ttctctcaca gtgtactcta 6200

 taagaggtgt gggtgtctgt ttggtcagga tgttagaaag tgctgataag 6250

 tagcatgatc agtgtatgcg aaaaggtttt taggaagtat ggcaaaaatg 6300

 ttgtattggc tatgatggtg acatgatata gtcagctgcc ttttaagagg 6350

 tcttatctgt tcagtgttaa gtgatttaaa aaaataataa cctgttttct 6400

 gactagttta aagatggatt tgaaaatggt tttgaatgca attaggttat 6450

 gctatttgga caataaactc accttgacct 6480

<210> 151
<211> 289
<212> PRT
<213> Homo sapien

<400> 151
 Met Glu Leu Leu Cys His Glu Val Asp Pro Val Arg Arg Ala Val
   1               5                  10                  15

 Arg Asp Arg Asn Leu Leu Arg Asp Asp Arg Val Leu Gln Asn Leu
                  20                  25                  30

 Leu Thr Ile Glu Glu Arg Tyr Leu Pro Gln Cys Ser Tyr Phe Lys
                  35                  40                  45

 Cys Val Gln Lys Asp Ile Gln Pro Tyr Met Arg Arg Met Val Ala
                  50                  55                  60

 Thr Trp Met Leu Glu Val Cys Glu Glu Gln Lys Cys Glu Glu Glu
                  65                  70                  75

 Val Phe Pro Leu Ala Met Asn Tyr Leu Asp Arg Phe Leu Ala Gly
                  80                  85                  90

 Val Pro Thr Pro Lys Ser His Leu Gln Leu Leu Gly Ala Val Cys
                  95                 100                 105

 Met Phe Leu Ala Ser Lys Leu Lys Glu Thr Ser Pro Leu Thr Ala
                 110                 115                 120

 Glu Lys Leu Cys Ile Tyr Thr Asp Asn Ser Ile Lys Pro Gln Glu
                 125                 130                 135

 Leu Leu Glu Trp Glu Leu Val Val Leu Gly Lys Leu Lys Trp Asn
                 140                 145                 150

 Leu Ala Ala Val Thr Pro His Asp Phe Ile Glu His Ile Leu Arg
                 155                 160                 165

 Lys Leu Pro Gln Gln Arg Glu Lys Leu Ser Leu Ile Arg Lys His
                 170                 175                 180

 Ala Gln Thr Phe Ile Ala Leu Cys Ala Thr Asp Phe Lys Phe Ala
                 185                 190                 195

 Met Tyr Pro Pro Ser Met Ile Ala Thr Gly Ser Val Gly Ala Ala
                 200                 205                 210

 Ile Cys Gly Leu Gln Gln Asp Glu Glu Val Ser Ser Leu Thr Cys
                 215                 220                 225

 Asp Ala Leu Thr Glu Leu Leu Ala Lys Ile Thr Asn Thr Asp Val
                 230                 235                 240

 Asp Cys Leu Lys Ala Cys Gln Glu Gln Ile Glu Ala Val Leu Leu
                 245                 250                 255

 Asn Ser Leu Gln Gln Tyr Arg Gln Asp Gln Arg Asp Gly Ser Lys
                 260                 265                 270

 Ser Glu Asp Glu Leu Asp Gln Ala Ser Thr Pro Thr Asp Val Arg
                 275                 280                 285

 Asp Ile Asp Leu


<210> 152
<211> 6480
<212> DNA
<213> Homo sapien

<400> 152
 agagcgagca ggggagagcg agaccagttt taaggggagg accggtgcga 50

 gtgaggcagc cccgaggctc tgctcgccca ccacccaatc ctcgcctccc 100

 ttctgctcca ccttctctct ctgccctcac ctctcccccg aaaaccccct 150

 atttagccaa aggaaggagg tcaggggaac gctctcccct ccccttccaa 200

 aaaacaaaaa cagaaaaacc cttttccagg ccggggaaag caggagggag 250

 aggggccgcc gggctggcca tggagctgct gtgccacgag gtggacccgg 300

 tccgcagggc cgtgcgggac cgcaacctgc tccgagacga ccgcgtcctg 350

 cagaacctgc tcaccatcga ggagcgctac cttccgcagt gctcctactt 400

 caagtgcgtg cagaaggaca tccaacccta catgcgcaga atggtggcca 450

 cctggatgct ggaggtctgt gaggaacaga agtgcgaaga agaggtcttc 500

 cctctggcca tgaattacct ggaccgtttc ttggctgggg tcccgactcc 550

 gaagtcccat ctgcaactcc tgggtgctgt ctgcatgttc ctggcctcca 600

 aactcaaaga gaccagcccg ctgaccgcgg agaagctgtg catttacacc 650

 gacaactcca tcaagcctca ggagctgctg gagtgggaac tggtggtgct 700

 ggggaagttg aagtggaacc tggcagctgt cactcctcat gacttcattg 750

 agcacatctt gcgcaagctg ccccagcagc gggagaagct gtctctgatc 800

 cgcaagcatg ctcagacctt cattgctctg tgtgccaccg actttaagtt 850

 tgccatgtac ccaccgtcga tgatcgcaac tggaagtgtg ggagcagcca 900

 tctgtgggct ccagcaggat gaggaagtga gctcgctcac ttgtgatgcc 950

 ctgactgagc tgctggctaa gatcaccaac acagacgtgg attgtctcaa 1000

 agcttgccag gagcagattg aggcggtgct cctcaatagc ctgcagcagt 1050

 accgtcagga ccaacgtgac ggatccaagt cggaggatga actggaccaa 1100

 gccagcaccc ctacagacgt gcgggatatc gacctgtgag gatgccagtt 1150

 gggccgaaag agagagacgc gtccataatc tggtctcttc ttctttctgg 1200

 ttgtttttgt tctttgtgtt ttagggtgaa acttaaaaaa aaaattctgc 1250

 ccccacctag atcatattta aagatctttt agaagtgaga gaaaaaggtc 1300

 ctacgaaaac ggaataataa aaagcatttg gtgcctattt gaagtacagc 1350

 ataagggaat cccttgtata tgcgaacagt tattgtttga ttatgtaaaa 1400

 gtaatagtaa aatgcttaca ggaaaacctg cagagtagtt agagaatatg 1450

 tatgcctgca atatgggaac aaattagagg agactttttt ttttcatgtt 1500

 atgagctagc acatacaccc ccttgtagta taatttcaag gaactgtgta 1550

 cgccatttat ggcatgatta gattgcaaag caatgaactc aagaaggaat 1600

 tgaaataagg agggacatga tggggaagga gtacaaaaca atctctcaac 1650

 atgattgaac catttgggat ggagaagcac ctttgctctc agccacctgt 1700

 tactaagtca ggagtgtagt tggatctcta cattaatgtc ctcttgctgt 1750

 ctacagtagc tgctacctaa aaaaagatgt tttattttgc cagttggaca 1800

 caggtgattg gctcctgggt ttcatgttct gtgacatcct gcttcttctt 1850

 ccaaatgcag ttcattgcag acaccaccat attgctatct aatggggaaa 1900

 tgtagctatg ggccataacc aaaactcaca tgaaacggag gcagatggag 1950

 accaagggtg ggatccagaa tggagtcttt tctgttattg tatttaaaag 2000

 ggtaatgtgg ccttggcatt tcttcttaga aaaaaactaa tttttggtgc 2050

 tgattggcat gtctggttca cagtttagca ttgttataaa ccattccatt 2100

 cgaaaagcac tttgaaaaat tgttcccgag cgatagatgg gatggtttat 2150

 gcaagtcatg ctgaatactc ctcccctctt ctcttttgcc ccctcccttc 2200

 ctgcccccag tctgggttac tcttcgcttc tggtatctgg cgttctttgg 2250

 tacacagttc tggtgttcct accaggactc aagagacacc ccttcctgct 2300

 gacattccca tcacaacatt cctcagacaa gcctgtaaac taaaatctgt 2350

 taccattctg atggcacaga aggatcttaa ttcccatctc tatacttctc 2400

 ctttggacat ggaaagaaaa gttattgctg gtgcaaagat agatggctga 2450

 acatcagggt gtggcatttt gttccctttt ccgttttttt tttttttatt 2500

 gttgttgtta attttattgc aaagttgtat tcagcgtact tgaatttttc 2550

 ttcctctcca cttcttagag gcattcagtt agcaaagagg ttggagcaac 2600

 aacttttttt tttttttttg cacaattgta attgacaggt aatgaagcta 2650

 tttgttaaaa tatttgcctt tttaagtaaa aaagaaaaat cagaacaggg 2700

 ctatttgaag aattatttta tacacagatt ctgccttgtt tcatagtatg 2750

 agggttgaag acggaaaaca atctaagggt ctctcatttt tttaattttg 2800

 ttttgttcag tttggttttt tttttttttt gcgctgctaa gaagctaaag 2850

 tcatccatcc ttattcacgt tgacagtacc tagctgtaat gtttcacaga 2900

 gtgtgctgct attttataaa catttttata atatattatt ttactgctta 2950

 aattccaagt cctgaagtag atggttgaga tatgagttct tcgtactgga 3000

 aaagcccttc cgtagtttgt tttcttctgg tagcatattc atggttgttt 3050

 ttttttttct tttttggttt tttggttttt tttttttcct ctgatcacat 3100

 tcttcaaaga cggagtattc tttacctcag gtttactgga caaaatcaat 3150

 aactacaaaa ggcaatgatt cacgcttttg ttttcataat acctcacaac 3200

 cgtacagttt ctgcttggga gcccattcgc atgaggaata cagaagcagt 3250

 gtgagcaggg ctgactccct ctcaggtgga aggcagggcg gtctcactcc 3300

 cagggacctt tttggtcatg gaggccatcg ggctcccagt tagaccctgg 3350

 tatcctcatc atgatggaaa aaatacattg aaccaaggga tcctccctcc 3400

 ccttcaaggc agacgttcag tacaaacatt tatgcggtag gctcagatgt 3450

 cgtaatttgc acttaggtac caggtgtcag gaaacagact aaaaagaatt 3500

 ccaccaggct gtttggagat cctcatcttg gagctttttc aaaagcgggg 3550

 cttcatctgc aaagggccct ttcatcttga agtttttccc ctccgtcttt 3600

 cccctcccct ggcatggaca ccttgtgttt aggatcatct ctgcaggttt 3650

 cctaggtctg aatctgcgag tagatgaacc tgcagcaagc agcgtttatg 3700

 gtgcttcctt ctccctcctc tgtctcaaac tgcgcaggca agcactatgc 3750

 aagcccaggc cctctgctga gcggtactaa acggtcgggt tttcaatcac 3800

 actgaattgg caggataaga aaaataggtc agataagtat gggatgatag 3850

 ttgaagggag gtgaagaggc tgcttctcta cagaggtgaa attccagatg 3900

 agtcagtctc ttgggaagtg tgtttagaag ggttcaggac tttgtgagtt 3950

 agcatgaccc taaaattcta ggggatttct ggtgggacaa tgggtggtga 4000

 attttgaagt tttggagagg gaagtggagc agccagcaag taagctagcc 4050

 agagttttct caagagccag ctttgctcag cacactctcc tgggccccaa 4100

 ggagtcccac ggaatgggga aagtgggaac cctggagttc ttgggaatct 4150

 tggagcctaa agagaaaccg aggtgcaaat tcatttcatg gtgactgacc 4200

 cttgagctta aacagaagca gcaaatgaaa gaaccggaca aataaggaag 4250

 ggcacaagcc tacccgactc tatttacagt ctgtaacttt ccactcttcc 4300

 tgtagtcccg aggcccctgg gtccttctag cttttctctt tcccatcctt 4350

 ggggccttgt gtgatgatgg gtgtggggct gccgatggga aagtcggggg 4400

 ttgttaggct tttctgcctg ctcctgctta aacacaagaa ggaatcctgg 4450

 attttgccct ctccttagct cttagtctct ttggtaggag ttttgttcca 4500

 gaggagctct cccccttgga tttgaacttg ctctttttgt tgttgttgtt 4550

 ctttctcttc tttttcttac ctcccactaa aggggttcca aattatcctg 4600

 gtctttttct accttgttgt gtttctatct cgtctttact tccatctgtt 4650

 tgtttttttc tccatcagtg ggggccgagt tgttccccca gcctgccaaa 4700

 ttttgatcct tcccctcttt tggccaaatc ctagggggaa gaaatcctag 4750

 tatgccaaaa atatatgcta agcataatta aactccatgc gggtccataa 4800

 cagccaagaa gcctgcagga gaaagccaag ggcagttccc tccgcagaac 4850

 accccatgcg tgctgagagg cgagctcctt gaagaagggg ctgttcttcc 4900

 aggaggcctt attttgaact gcctcaggac cccactggag agcacagcat 4950

 gccttactac tgggtcatcc ttggtctatg tgctctgtac tggaggctct 5000

 gttctgcctc ttatcagcca ggtcaggggc acacatggct taagtgacaa 5050

 agccagagga gaagacaacc ctgacagcat cacgctgcat cccattgcta 5100

 gcaggattgg caactcttca gacggagctg cgcttccctg cagtctagca 5150

 cctctagggc ctctccagac tgtgccctgg gagctctggg actgaaaggt 5200

 taagaacata aggcaggatc agatgactct ctccaagagg gcaggggaat 5250

 tttctctcca tgggccacag gggacagggc tgggagaaga aatagacttg 5300

 caccttatgt catgtaaata attgattttc tagttcaaga agataatatt 5350

 ggtagtgtgg gaattggagg taggaagggg aggaagtctg agtaagccag 5400

 ttggcttcta agccaaaagg attcctcttt gtttatctct gagacagtcc 5450

 aaccttgaga atagctttaa aagggaaatt aatgctgaga tgataaagtc 5500

 cccttaagcc aacaaaccct ctgtagctat agaatgagtg caggtttcta 5550

 ttggtgtgga ctcagagcaa tttacaagag ctgttcatgc agccatccat 5600

 ttgtgcaaaa tagggtaaga agattcaaga ggatatttat tacttcctca 5650

 taccacatgg cttttgatga ttctggattc taaacaaccc agaatggtca 5700

 tttcaggcac aacgatacta cattcgtgtg tgtctgcttt taaacttggc 5750

 tgggctatca gaccctattc tcggctcagg ttttgagaag ccatcagcaa 5800

 atgtgtacgt gcatgctgta gctgcagcct gcatcccttc gcctgcagcc 5850

 tactttgggg aaataaagtg ccttactgac tgtagccatt acagtatcca 5900

 atgtcttttg acaggtgcct gtccttgaaa aacaaagttt ctatttttat 5950

 ttttaattgg tttagttctt aactgctggc caactcttac atccccagca 6000

 aatcatcggg ccattggatt ttttccatta tgttcatcac ccttatatca 6050

 tgtacctcag atctctctct ctctcctctc tctcagttat atagtttctt 6100

 gtcttggact ttttttttct tttctttttc tttttttttt tgctttaaaa 6150

 caagtgtgat gccatatcaa gtccatgtta ttctctcaca gtgtactcta 6200

 taagaggtgt gggtgtctgt ttggtcagga tgttagaaag tgctgataag 6250

 tagcatgatc agtgtatgcg aaaaggtttt taggaagtat ggcaaaaatg 6300

 ttgtattggc tatgatggtg acatgatata gtcagctgcc ttttaagagg 6350

 tcttatctgt tcagtgttaa gtgatttaaa aaaataataa cctgttttct 6400

 gactagttta aagatggatt tgaaaatggt tttgaatgca attaggttat 6450

 gctatttgga caataaactc accttgacct 6480

<210> 153
<211> 289
<212> PRT
<213> Homo sapien

<400> 153
 Met Glu Leu Leu Cys His Glu Val Asp Pro Val Arg Arg Ala Val
   1               5                  10                  15

 Arg Asp Arg Asn Leu Leu Arg Asp Asp Arg Val Leu Gln Asn Leu
                  20                  25                  30

 Leu Thr Ile Glu Glu Arg Tyr Leu Pro Gln Cys Ser Tyr Phe Lys
                  35                  40                  45

 Cys Val Gln Lys Asp Ile Gln Pro Tyr Met Arg Arg Met Val Ala
                  50                  55                  60

 Thr Trp Met Leu Glu Val Cys Glu Glu Gln Lys Cys Glu Glu Glu
                  65                  70                  75

 Val Phe Pro Leu Ala Met Asn Tyr Leu Asp Arg Phe Leu Ala Gly
                  80                  85                  90

 Val Pro Thr Pro Lys Ser His Leu Gln Leu Leu Gly Ala Val Cys
                  95                 100                 105

 Met Phe Leu Ala Ser Lys Leu Lys Glu Thr Ser Pro Leu Thr Ala
                 110                 115                 120

 Glu Lys Leu Cys Ile Tyr Thr Asp Asn Ser Ile Lys Pro Gln Glu
                 125                 130                 135

 Leu Leu Glu Trp Glu Leu Val Val Leu Gly Lys Leu Lys Trp Asn
                 140                 145                 150

 Leu Ala Ala Val Thr Pro His Asp Phe Ile Glu His Ile Leu Arg
                 155                 160                 165

 Lys Leu Pro Gln Gln Arg Glu Lys Leu Ser Leu Ile Arg Lys His
                 170                 175                 180

 Ala Gln Thr Phe Ile Ala Leu Cys Ala Thr Asp Phe Lys Phe Ala
                 185                 190                 195

 Met Tyr Pro Pro Ser Met Ile Ala Thr Gly Ser Val Gly Ala Ala
                 200                 205                 210

 Ile Cys Gly Leu Gln Gln Asp Glu Glu Val Ser Ser Leu Thr Cys
                 215                 220                 225

 Asp Ala Leu Thr Glu Leu Leu Ala Lys Ile Thr Asn Thr Asp Val
                 230                 235                 240

 Asp Cys Leu Lys Ala Cys Gln Glu Gln Ile Glu Ala Val Leu Leu
                 245                 250                 255

 Asn Ser Leu Gln Gln Tyr Arg Gln Asp Gln Arg Asp Gly Ser Lys
                 260                 265                 270

 Ser Glu Asp Glu Leu Asp Gln Ala Ser Thr Pro Thr Asp Val Arg
                 275                 280                 285

 Asp Ile Asp Leu


<210> 154
<211> 6478
<212> DNA
<213> Homo sapien

<400> 154
 agagcgagca ggggagagcg agaccagttt taaggggagg accggtgcga 50

 gtaaggcagc cccgaggctc tgctcgccca ccacccaatc ctcgcctccc 100

 ttctgctcca ccttctctct ctgccctcac ctctcccccg aaaaccccct 150

 atttagccaa aggaaggagg tcaggggaac gctctcccct ccccttccaa 200

 aaaacaaaaa cagaaaaacc cttttccagg ccggggaaag caggagggag 250

 aggggccgcc gggctggcca tggagctgct gtgccacgag gtggacccgg 300

 tccgcagggc cgtgcgggac cgcaacctgc tccgagacga ccgcgtcctg 350

 cagaacctgc tcaccatcga ggagcgctac cttccgcagt gctcctactt 400

 caagtgcgtg cagaaggaca tccaacccta catgcgcaga atggtggcca 450

 cctggatgct ggaggtctgt gaggaacaga agtgcgaaga agaggtcttc 500

 cctctggcca tgaattacct ggaccgtttc ttggctgggg tcccgactcc 550

 gaagtcccat ctgcaactcc tgggtgctgt ctgcatgttc ctggcctcca 600

 aactcaaaga gaccagcccg ctgaccgcgg agaagctgtg catttacacc 650

 gacaactcca tcaagcctca ggagctgctg gagtgggaac tggtggtgct 700

 ggggaagttg aagtggaacc tggcagctgt cactcctcat gacttcattg 750

 agcacatctt gcgcaagctg ccccagcagc gggagaagct gtctctgatc 800

 cgcaagcatg ctcagacctt cattgctctg tgtgccaccg actttaagtt 850

 tgccatgtac ccaccgtcga tgatcgcaac tggaagtgtg ggagcagcca 900

 tctgtgggct ccagcaggat gaggaagtga gctcgctcac ttgtgatgcc 950

 ctgactgagc tgctggctaa gatcaccaac acagacgtgg attgtctcaa 1000

 agcttgccag gagcagattg aggcggtgct cctcaatagc ctgcagcagt 1050

 accgtcagga ccaacgtgac ggatccaagt cggaggatga actggaccaa 1100

 gccagcaccc ctacagacgt gcgggatatc gacctgtgag gatgccagtt 1150

 gggccgaaag agagagacgc gtccataatc tggtctcttc ttctttctgg 1200

 ttgtttttgt tctttgtgtt ttagggtgaa acttaaaaaa aaaattctgc 1250

 ccccacctag atcatattta aagatctttt agaagtgaga gaaaaaggtc 1300

 ctacgaaaac ggaataataa aaagcatttg gtgcctattt gaagtacagc 1350

 ataagggaat cccttgtata tgcgaacagt tattgtttga ttatgtaaaa 1400

 gtaatagtaa aatgcttaca ggaaaacctg cagagtagtt agagaatatg 1450

 tatgcctgca atatgggaac aaattagagg agactttttt tttcatgtta 1500

 tgagctagca catacacccc cttgtagtat aatttcaagg aactgtgtac 1550

 gccatttatg gcatgattag attgcaaagc aatgaactca agaaggaatt 1600

 gaaataagga gggacatgat ggggaaggag tacaaaacaa tctctcaaca 1650

 tgattgaacc atttgggatg gagaagcacc tttgctctca gccacctgtt 1700

 actaagtcag gagtgtagtt ggatctctac attaatgtcc tcttgctgtc 1750

 tacagtagct gctacctaaa aaaagatgtt ttattttgcc agttggacac 1800

 aggtgattgg ctcctgggtt tcatgttctg tgacatcctg cttcttcttc 1850

 caaatgcagt tcattgcaga caccaccata ttgctatcta atggggaaat 1900

 gtagctatgg gccataacca aaactcacat gaaacggagg cagatggaga 1950

 ccaagggtgg gatccagaat ggagtctttt ctgttattgt atttaaaagg 2000

 gtaatgtggc cttggcattt cttcttagaa aaaaactaat ttttggtgct 2050

 gattggcatg tctggttcac agtttagcat tgttataaac cattccattc 2100

 gaaaagcact ttgaaaaatt gttcccgagc gatagatggg atggtttatg 2150

 caagtcatgc tgaatactcc tcccctcttc tcttttgccc cctcccttcc 2200

 tgcccccagt ctgggttact cttcgcttct ggtatctggc gttctttggt 2250

 acacagttct ggtgttccta ccaggactca agagacaccc cttcctgctg 2300

 acattcccat cacaacattc ctcagacaag cctgtaaact aaaatctgtt 2350

 accatctgat ggcacagaag gatcttaatt cccatctcta tacttctcct 2400

 ttggacatgg aaagaaaagt tattgctggt gcaaagatag atggctgaac 2450

 atcagggtgt ggcattttgt tcccttttcc gttttttttt tttttattgt 2500

 tgttgttaat tttattgcaa agttgtattc agcgtacttg aatttttctt 2550

 cctctccact tcttagaggc attcagttag caaagaggtt ggagcaacaa 2600

 cttttttttt ttttttttgc acaattgtaa ttgacaggta atgaagctat 2650

 ttgttaaaat atttgccttt ttaagtaaaa aagaaaaatc agaacagggc 2700

 tatttgaaga attattttat acacagattc tgccttgttt catagtatga 2750

 gggttgaaga cggaaaacaa tctaagggtc tctcattttt ttaattttgt 2800

 tttgttcagt ttggtttttt tttttttttg cgctgctaag aagctaaagt 2850

 catccatcct tattcacgtt gacagtacct agctgtaatg tttcacagag 2900

 tgtgctgcta ttttataaac atttttataa tatattattt tactgcttaa 2950

 attccaagtc ctgaagtaga tggttgagat atgagttctt cgtactggaa 3000

 aagcccttcc gtagtttgtt ttcttctggt agcatattca tggttgtttt 3050

 tttttttctt ttttggtttt ttggtttttt ttttttcctc tgatcacatt 3100

 cttcaaagac ggagtattct tacctcaggt ttactggaca aaatcaataa 3150

 ctacaaaagg caatgattca cgcttttgtt ttcataatac ctcacaaccg 3200

 tacagtttct gcttgggagc ccattcgcat gaggaataca gaagcagtgt 3250

 gagcagggct gactccctct caggtggaag gcagggcggt ctcactccca 3300

 gggacctttt tggtcatgga ggccatcggg ctcccagtta gaccctggta 3350

 tcctcatcat gatggaaaaa atacattgaa ccaagggatc ctccctcccc 3400

 ttcaaggcag acgttcagta caaacattta tgcggtaggc tcagatgtcg 3450

 taatttgcac ttaggtacca ggtgtcagga aacagactaa aaagaattcc 3500

 accaggctgt ttggagatcc tcatcttgga gctttttcaa aagcggggct 3550

 tcatctgcaa agggcccttt catcttgaag tttttcccct ccgtctttcc 3600

 cctcccctgg catggacacc ttgtgtttag gatcatctct gcaggtttcc 3650

 taggtctgaa tctgcgagta gatgaacctg cagcaagcag cgtttatggt 3700

 gcttccttct ccctcctctg tctcaaactg cgcaggcaag cactatgcaa 3750

 gcccaggccc tctgctgagc ggtactaaac ggtcgggttt tcaatcacac 3800

 tgaattggca ggataagaaa aataggtcag ataagtatgg gatgatagtt 3850

 gaagggaggt gaagaggctg cttctctaca gaggtgaaat tccagatgag 3900

 tcagtctctt gggaagtgtg tttagaaggg ttcaggactt tgtgagttag 3950

 catgacccta aaattctagg ggatttctgg tgggacaatg ggtggtgaat 4000

 tttgaagttt tggagaggga agtggagcag ccagcaagta agctagccag 4050

 agttttctca agagccagct ttgctcagca cactctcctg ggccccaagg 4100

 agtcccacgg aatggggaaa gtgggaaccc tggagttctt gggaatcttg 4150

 gagcctaaag agaaaccgag gtgcaaattc atttcatggt gactgaccct 4200

 tgagcttaaa cagaagcagc aaatgaaaga accggacaaa taaggaaggg 4250

 cacaagccta cccgactcta tttacagtct gtaactttcc actcttcctg 4300

 tagtcccgag gcccctgggt ccttctagct tttctctttc ccatccttgg 4350

 ggccttgtgt gatgatgggt gtggggctgc cgatgggaaa gtcgggggtt 4400

 gttaggcttt tctgcctgct cctgcttaaa cacaagaagg aatcctggat 4450

 tttgccctct ccttagctct tagtctcttt ggtaggagtt ttgttccaga 4500

 ggagctctcc cccttggatt tgaacttgct ctttttgttg ttgttgttct 4550

 ttctcttctt tttcttacct cccactaaag gggttccaaa ttatcctggt 4600

 ctttttctac cttgttgtgt ttctatctcg tctttacttc catctgtttg 4650

 tttttttctc catcagtggg ggccgagttg ttcccccagc ctgccaaatt 4700

 ttgatccttc ccctcttttg gccaaatcct agggggaaga aatcctagta 4750

 tgccaaaaat atatgctaag cataattaaa ctccatgcgg gtccataaca 4800

 gccaagaagc ctgcaggaga aagccaaggg cagttccctc cgcagaacac 4850

 cccatgcgtg ctgagaggcg agctccttga agaaggggct gttcttccag 4900

 gaggccttat tttgaactgc ctcaggaccc cactggagag cacagcatgc 4950

 cttactactg ggtcatcctt ggtctatgtg ctctgtactg gaggctctgt 5000

 tctgcctctt atcagccagg tcaggggcac acatggctta agtgacaaag 5050

 ccagaggaga agacaaccct gacagcatca cgctgcatcc cattgctagc 5100

 aggattggca actcttcaga cggagctgcg cttccctgca gtctagcacc 5150

 tctagggcct ctccagactg tgccctggga gctctgggac tgaaaggtta 5200

 agaacataag gcaggatcag atgactctct ccaagagggc aggggaattt 5250

 tctctccatg ggccacaggg gacagggctg ggagaagaaa tagacttgca 5300

 ccttatgtca tgtaaataat tgattttcta gttcaagaag ataatattgg 5350

 tagtgtggga attggaggta ggaaggggag gaagtctgag taagccagtt 5400

 ggcttctaag ccaaaaggat tcctctttgt ttatctctga gacagtccaa 5450

 ccttgagaat agctttaaaa gggaaattaa tgctgagatg ataaagtccc 5500

 cttaagccaa caaaccctct gtagctatag aatgagtgca ggtttctatt 5550

 ggtgtggact cagagcaatt tacaagagct gttcatgcag ccatccattt 5600

 gtgcaaaata gggtaagaag attcaagagg atatttatta cttcctcata 5650

 ccacatggct tttgatgatt ctggattcta aacaacccag aatggtcatt 5700

 tcaggcacaa cgatactaca ttcgtgtgtg tctgctttta aacttggctg 5750

 ggctatcaga ccctattctc ggctcaggtt ttgagaagcc atcagcaaat 5800

 gtgtacgtgc atgctgtagc tgcagcctgc atcccttcgc ctgcagccta 5850

 ctttggggaa ataaagtgcc ttactgactg tagccattac agtatccaat 5900

 gtcttttgac aggtgcctgt ccttgaaaaa caaagtttct atttttattt 5950

 ttaattggtt tagttcttaa ctgctggcca actcttacat ccccagcaaa 6000

 tcatcgggcc attggatttt ttccattatg ttcatcaccc ttatatcatg 6050

 tacctcagat ctctctctct ctcctctctc tcagttatat agtttcttgt 6100

 cttggacttt ttttttcttt tctttttctt tttttttttg ctttaaaaca 6150

 agtgtgatgc catatcaagt ccatgttatt ctctcacagt gtactctata 6200

 agaggtgtgg gtgtctgttt ggtcaggatg ttagaaagtg ctgataagta 6250

 gcatgatcag tgtatgcgaa aaggttttta ggaagtatgg caaaaatgtt 6300

 gtattggcta tgatggtgac atgatatagt cagctgcctt ttaagaggtc 6350

 ttatctgttc agtgttaagt gatttaaaaa aataataacc tgttttctga 6400

 ctagtttaaa gatggatttg aaaatggttt tgaatgcaat taggttatgc 6450

 tatttggaca ataaactcac cttgacct 6478

<210> 155
<211> 289
<212> PRT
<213> Homo sapien

<400> 155
 Met Glu Leu Leu Cys His Glu Val Asp Pro Val Arg Arg Ala Val
   1               5                  10                  15

 Arg Asp Arg Asn Leu Leu Arg Asp Asp Arg Val Leu Gln Asn Leu
                  20                  25                  30

 Leu Thr Ile Glu Glu Arg Tyr Leu Pro Gln Cys Ser Tyr Phe Lys
                  35                  40                  45

 Cys Val Gln Lys Asp Ile Gln Pro Tyr Met Arg Arg Met Val Ala
                  50                  55                  60

 Thr Trp Met Leu Glu Val Cys Glu Glu Gln Lys Cys Glu Glu Glu
                  65                  70                  75

 Val Phe Pro Leu Ala Met Asn Tyr Leu Asp Arg Phe Leu Ala Gly
                  80                  85                  90

 Val Pro Thr Pro Lys Ser His Leu Gln Leu Leu Gly Ala Val Cys
                  95                 100                 105

 Met Phe Leu Ala Ser Lys Leu Lys Glu Thr Ser Pro Leu Thr Ala
                 110                 115                 120

 Glu Lys Leu Cys Ile Tyr Thr Asp Asn Ser Ile Lys Pro Gln Glu
                 125                 130                 135

 Leu Leu Glu Trp Glu Leu Val Val Leu Gly Lys Leu Lys Trp Asn
                 140                 145                 150

 Leu Ala Ala Val Thr Pro His Asp Phe Ile Glu His Ile Leu Arg
                 155                 160                 165

 Lys Leu Pro Gln Gln Arg Glu Lys Leu Ser Leu Ile Arg Lys His
                 170                 175                 180

 Ala Gln Thr Phe Ile Ala Leu Cys Ala Thr Asp Phe Lys Phe Ala
                 185                 190                 195

 Met Tyr Pro Pro Ser Met Ile Ala Thr Gly Ser Val Gly Ala Ala
                 200                 205                 210

 Ile Cys Gly Leu Gln Gln Asp Glu Glu Val Ser Ser Leu Thr Cys
                 215                 220                 225

 Asp Ala Leu Thr Glu Leu Leu Ala Lys Ile Thr Asn Thr Asp Val
                 230                 235                 240

 Asp Cys Leu Lys Ala Cys Gln Glu Gln Ile Glu Ala Val Leu Leu
                 245                 250                 255

 Asn Ser Leu Gln Gln Tyr Arg Gln Asp Gln Arg Asp Gly Ser Lys
                 260                 265                 270

 Ser Glu Asp Glu Leu Asp Gln Ala Ser Thr Pro Thr Asp Val Arg
                 275                 280                 285

 Asp Ile Asp Leu


<210> 156
<211> 442
<212> DNA
<213> Rattus norvegicus

<400> 156
 cttcctttcc aacttggacg ctgcagaatg gctcccgcaa agaagggtgg 50

 cgagaagaaa aagggccgtt ctgccatcaa cgaagtggta acccgagaat 100

 acaccatcaa cattcacaag cgcatccatg gagtgggctt caagaagcgt 150

 gcacctcggg cactcaaaga gattcggaaa tttgccatga aggagatggg 200

 aactccagat gtgcgcattg acaccaggct caacaaagct gtctgggcca 250

 aaggaataag gaatgtgcca taccgaatcc gtgtgcggct gtccagaaaa 300

 cgtaatgagg atgaagattc accaaataag ctatatactt tggttaccta 350

 tgtacctgtt accactttca aaaatctaca gacagtcaat gtggatgaga 400

 actaatcgct gatcgtcaga tcaaataaag ttataaaatt gc 442

<210> 157
<211> 125
<212> PRT
<213> Rattus norvegicus

<400> 157
 Met Ala Pro Ala Lys Lys Gly Gly Glu Lys Lys Lys Gly Arg Ser
   1               5                  10                  15

 Ala Ile Asn Glu Val Val Thr Arg Glu Tyr Thr Ile Asn Ile His
                  20                  25                  30

 Lys Arg Ile His Gly Val Gly Phe Lys Lys Arg Ala Pro Arg Ala
                  35                  40                  45

 Leu Lys Glu Ile Arg Lys Phe Ala Met Lys Glu Met Gly Thr Pro
                  50                  55                  60

 Asp Val Arg Ile Asp Thr Arg Leu Asn Lys Ala Val Trp Ala Lys
                  65                  70                  75

 Gly Ile Arg Asn Val Pro Tyr Arg Ile Arg Val Arg Leu Ser Arg
                  80                  85                  90

 Lys Arg Asn Glu Asp Glu Asp Ser Pro Asn Lys Leu Tyr Thr Leu
                  95                 100                 105

 Val Thr Tyr Val Pro Val Thr Thr Phe Lys Asn Leu Gln Thr Val
                 110                 115                 120

 Asn Val Asp Glu Asn
                 125

<210> 158
<211> 7581
<212> DNA
<213> Homo sapien

<400> 158
 tagacagtaa ggagccaggg gaacagagag aattgtgggg cagcaccgct 50

 ccttgggtcc ccactcccca tttctcattg cttggaaatc catgccaaga 100

 tgcctgcctt ccttggtcta aagtgtctgg ggaaattgtg cagctctgag 150

 aaaagcaaag tcacctcatc tgagagaacc agtgccaggg gctcgaacag 200

 aaagagactg attgttgagg accggagggt ctctgggacc tccttcaccg 250

 ctcataggcg tgccactatc actcatttgc tgtatctctg tcccaaggac 300

 tactgcccac gtgggcgtgt atgtaacagc gttgatcctt ttgtggccca 350

 ccctcaggac cctcaccacc catcagagaa gcctgtcatt cactgccata 400

 aatgtgggga gccttgcaag ggtgaagtgc ttcgggtcca gaccaaacat 450

 ttccacatca agtgtttcac ctgcaaagtg tgtggctgtg acctggcaca 500

 agggggcttc ttcataaaga acggagagta tctctgcacc ctggactacc 550

 agcggatgta cgggacacgc tgccatggct gtggggagtt cgtggagggc 600

 gaagtggtga ctgctctggg caagacctac catcccaatt gctttgcttg 650

 tactatctgc aagcgcccgt ttccacccgg agaccgagtc acattcaatg 700

 ggagagactg cctttgtcaa ctctgtgcac agccgatgtc gtccagtccg 750

 aaagaaacca ccttctccag caattgtgcc ggctgcggaa gagatatcaa 800

 gaacgggcag gcgctgctgg cgctggataa gcagtggcac ttggggtgct 850

 ttaaatgcaa gtcctgcggg aaggtcctca ccggggagta catcagcaag 900

 gatggtgctc cgtactgtga aaaggactac cagggactct ttggggtgaa 950

 atgtgaggcg tgtcaccagt ttatcacagg gaaagtcctg gaggcaggtg 1000

 acaaacatta ccaccccagc tgtgcacgat gcagcagatg caaccagatg 1050

 ttcacagaag gagaggaaat gtatcttcaa ggctccaccg tttggcatcc 1100

 cgactgtaag caatctacga agaccgagga aaagctgcgg cctaccagga 1150

 catcctcgga aagtatttat tctaggccag gctccagtat tcctggctca 1200

 ccaggtcata ctatctatgc aaaagtagac aatgagatcc tggattacaa 1250

 ggatttagca gccattccga aggtcaaggc aatttatgac attgaacgtc 1300

 cagatcttat tacctatgag cctttctaca cttcgggcta tgatgacaaa 1350

 caggagagac agagccttgg agagtctccg aggactttgt ctcctactcc 1400

 atcagcagaa gggtaccagg atgttcggga tcggatgatc catcggtcca 1450

 cgagccaggg ctccatcaac tcccctgtgt acagccgcca cagctacact 1500

 ccaaccacgt cccgctctcc ccagcatttc cacagacctg gcaatgagcc 1550

 gtccagcggc cggaactccc ctctccctta ccggccagac agccgccctc 1600

 taactccaac ttacgctcag gcccctaaac atttccatgt tccagatcaa 1650

 ggaatcaaca tttaccgaaa gccacccatc tacaaacagc atgctgcctt 1700

 ggcagcccag agcaagtcct cagaagatat catcaagttt tccaagttcc 1750

 cagcagccca ggcaccagac cccagcgaga caccagagat tgagacggac 1800

 cactggcctg gtcccccctc atttgctgtc ataggacctg acatgaaacg 1850

 cagatctagt ggcagagagg aagatgatga ggaacttctg agacgtcggc 1900

 agcttcaaga agagcaatta atgaagctta actcaggcct gggacagttg 1950

 atcttgaaag aagagatgga gaaagagagc cgggaaaggt catctctgtt 2000

 agccagtcgc tacgattctc ccatcaactc agcttcacat attccatcat 2050

 ctaaaactgc atctctccct ggctatggaa gaaatgggct tcaccggcct 2100

 gtttctaccg acttcgctca gtataacagc tatggggatg tcagcggggg 2150

 agtgcgagat taccagacac tcccagatgg ccacatgcct gcaatgagaa 2200

 tggaccgagg agtgtctatg cccaacatgt tggaaccaaa gatatttcca 2250

 tatgaaatgc tcatggtgac caacagaggg cgaaacaaaa tcctcagaga 2300

 ggtggacaga accaggctgg agcgccactt agcccctgaa gtgtttcggg 2350

 aaatctttgg aatgtccata caggagtttg acaggttacc tctttggaga 2400

 cgcaacgaca tgaagaaaaa agcaaaactc ttctaagtcc cactcgtgaa 2450

 tggcaattag agaaaggact gacagtggcg gtgccccata ggatgtcata 2500

 ttgaggccca aacttgattg gagaatttgc aaactaccgt cgctcagcaa 2550

 caccaaaaag agaaagtctg gttaaaacac catgagtcaa atgtcgggcc 2600

 agccaacagt aacacttgcc aagaagcatg gcgtagaaat ttctatgttc 2650

 cgaaacacag agtagtgtcc acatgtgacc ttttcacatt accttatgta 2700

 tacaacagga gctgcgttgt tttcttcttt ttcttttcct ttatctgttg 2750

 tccaacaaca gtgctgactg tccggataag agctggcaag tgcccttagg 2800

 atgccgcatg ggaaaaatcg gttatcataa tttcaaagta taaatatatt 2850

 tattatgtag cgctgcggct aagaaggaag agtgaggggt ctgtccatgg 2900

 ggtggcagtg atttcacacc cgcctttctt gaatggcttc gtgttactca 2950

 gccgtgccct ggcaggaatg gaactccatc agggaacagg gcagctctgt 3000

 ttgaatgggg tgaaaaacag caaaattaat tcttagcaag ctccttgttc 3050

 tctactgttc accgggacct ggctggcaaa tgacttagct attagtatat 3100

 ttaaaaactg ttcaaaagca aaagagaagg aacaggaatg aaaggaaacc 3150

 ttcccttaac tctttctgct tcccatagca ggtctggttc ctgctccccg 3200

 cctaggacag gagctgtctg gagctccacc tttgcaaaga aaggaaaaac 3250

 acaaattgcc cccagattgg cccagtggca tgccattagg tgattttgcg 3300

 taggggccat atcattcatg gccaaaaaaa accaaaaagc aaaaaacaaa 3350

 aacaagtccc atgtcctact gactctagtt cttccagtcg ttatcctctg 3400

 ctgtctctct ggcatcctat gaatcagatc aagcccatgc tgttgttggt 3450

 ttttaaggtt tctttcaata ataggctaag gaaagacatg tttttctctt 3500

 ttaaatctct gcaactccaa agtagactcc ttcgaacgta tttaatttgg 3550

 ccttttcagc tttcttcttg cccagctctg tcgaattcat gggtgtgtgt 3600

 gcacatgttg gtttcactca cccagagtaa ttttgtgagc atgcatgtgc 3650

 tttttaattt ctgcttgaat gtttgtcctg ctgtgttgca gcttctaaag 3700

 acattgtcac cgagtgtgtg tgactcaaag atcaagagtg aggctaaact 3750

 gcgaccccaa catcacttcc ttcatggaaa ggtgttggcg ctgatgtagc 3800

 tcatggaagg atcagactgg gaaccacaga ggaaggatga ggtgggatgt 3850

 ggaggtcaga gcatctcacg agagtccctc aggctctgca acactagatt 3900

 cgaatatgag cctagggttt ccccaacacg tgcgtgcata tgaaaccaca 3950

 tcatgattcc cgacgtgagt tagatgaggg agagtttgtg taactccaca 4000

 cccaggaggg taagccactt tattatcatg ctttggggct gtgcttaaga 4050

 atttaagctc tgttttaaag ccgaagaaga aaacatttga atttaccttc 4100

 atatgccact aagaacaaaa gctctgaagt tcttcctgct ggcaccaaat 4150

 attaggatta caagctgtct ctctgacacc agtggtaaaa aagcaagtag 4200

 aatagtttct gagtctgtgt tgcagcctct gacacgtggc tcactgctgt 4250

 catttggggg gtggaatgaa cagtcactgt tctatagcat cctcctgtgc 4300

 tcttacctaa ggaatctaaa ttgtcctagc cttccattgc tatgcactga 4350

 atgaggacta ctctcgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg 4400

 tgtgtgtgtg tgttggatct actaacatgt ttagcaaatg gctctgacag 4450

 ggtggccatg agcagatgag accagctctt gcttggttgg aagccacact 4500

 gcagtttgca gtttagcctt tggtgtctca gtggcctctt gcttattcca 4550

 tgctttttct atcccatcct ctctctgtgc cctcctgcaa tggcagcctt 4600

 ggcacaatgc ctgggtgtcc tcatccttgc tttactctgg aaagtgtggg 4650

 gatggagagg atggtgcatt tccagtgctt ccttacctgt caataacaat 4700

 ggtggccacc tgggtcccag cacttggctg gtggagagat ttttttcatt 4750

 atggagctaa taaagggtcc ctacgtttta cattgattaa tgaattatca 4800

 cccagacatg tgcagatgaa atgtcaatat aagaaaaatc aaggtatttg 4850

 ggaaacatgg gcataatcag gtagttttgc taaaattcct cttccttggt 4900

 ctacataaag aagacatggg tctgtcatag aatggggaca ttagactgaa 4950

 aactgggaca acccccttcc ttattttata gagactagga gttaaggggc 5000

 ctgcctaaga ttgcagtgat aaagaactga accctaaatc agctcccact 5050

 aatgaaaccc tgctttcctt gtatctttta aactcagttc tgcatccaac 5100

 ttgagaagaa aaaaagcttc tttccatatc aagtaccata tgagttcatt 5150

 taaactgcac cttgcagaaa tgcattgcca gaaagcacca gtagcctcct 5200

 atctgcaagc agagtagtgc tctgctctgg ggaggggtca ttggaaacca 5250

 taatgcagag tgggccccct actccatttc ccagcaaaag gctccagctg 5300

 gagggatggg ttgtggggca acctggttcc tgctaactgc cagattgaat 5350

 gtgtgggcta gaatgcctgc gcatttagtt aaactgggct cagcatgctt 5400

 gtcctcaaaa tgtccatcct ggtcacagca cacaagatgg ctattggtct 5450

 gcttttaccc taccctgtac tatacatgaa aattccagtt attaacacac 5500

 tcaaactggt ggagcttgtt caccctagga aggggattgt atatatggca 5550

 ggcttccctg gtgccgatgt aaagggctac atttgggaac atttgacttc 5600

 cttgggactc ttaagtgcat actgatggca tgaagtaaaa ggggcctcaa 5650

 tgatgatagg aaaatcagtt cttttaaaat ttcttcaaga aaatccaggc 5700

 tatcacatag tctttctgtg tgacttatta ggagatagga agagcattgg 5750

 gaaacttgca cagctagcta tgcatctaca ttttggtttg gggttagtta 5800

 tgaaatgttc ttaatatgac gtgttcaata acttcacata aacttcctgt 5850

 tctccaaaac ctcaaagaga tagagttaat gagttgttgt ttttttttaa 5900

 atgggggtag ttttctatct gtcatgggct ctagcatcta ctccgctacc 5950

 caattctgtc atctccaagc tgagtttcct cttctgaggc agaggctgga 6000

 gcagttcttt ttcagttctc atcctctcca tcccaatcca gtatatcaat 6050

 caactctaac tcggagacgt ctagctggca atgtttctaa aactttcact 6100

 ggatttcttt agacattgaa gcaaacattt ttttctaaga attgcttctc 6150

 agatgatgat atcaaatgta tatgcttttg caagtttgaa aagttcaaat 6200

 taaccacttt tgactaggta agtctttcta aaaaccattt aaagctaact 6250

 gggtcttagc atcctcctgt gtatggaaga gacaggtgac cgctccaggt 6300

 tgggtgctca cagaaccctt ttcctgactc tcatggaaga tggtggaagg 6350

 aaaatagact gtctcatcaa ccctcctgtg tcctctgaag caatctcagt 6400

 ttttattaac cacctcttct gtgtttctgg tagctattta acctgtattt 6450

 aatctgtact tcctatgcca gcctcaattt tatttgattt ttaaaattat 6500

 tctcttctaa ccaatgaagt gtttgtcagt atgccccaaa gcttgctctt 6550

 ttgtgctccc ttttgaataa ctttctatcc agaaaaagag attatttggg 6600

 acttgagatt tgcagtgata ccaacttata gcaatgatgt actttaaggg 6650

 aactacccaa ctatgttgtg atagaagaaa gagaaacctt cactttggca 6700

 ttttttttaa tcactgttta tttttctgtt tgcggcccag gaagcagtgg 6750

 gaggtggtgg cagatatgct ttgcatatgg attgttatgt ttttatttgg 6800

 gcaagtttaa tcatggaaaa ctcaaaaaga aggggggaaa tggtcagttt 6850

 aagccaaaag aaactttcta aacaatgtat aggtacacag caaaattaaa 6900

 caaatccaac aatttctgaa gcttagtgta attgagtggt ggttgttatt 6950

 caataaaatt attcccaaaa gtgtttctcc taagagtgca gttcccatga 7000

 gtcacttcct gaacccattg accaaaggtg gacagagaca atcctgtaga 7050

 ccttgacatt cagaaagatg tgagctgctt actgatcata tatgcatacg 7100

 tttctttaca gcagaggaaa ccattgtcca caaaactgat gttcttttgg 7150

 ggttttatgt acagacttgt ccaatcatgt gtgtggttcc tgcgagttgc 7200

 tgatgactcc gcattgaagc tctctgagtt ctttgatttt aagttgggtt 7250

 tatggaattt tttcaaatgt tggaaggcgt gtggttcttc ctgccctccc 7300

 tccccttttg gaaatatgaa agcaaatgtt tagaagaatt ccttttgaaa 7350

 agctgtgtcg tgttccctgt gaaactgagc aggtgtgtgt tggcgcgcta 7400

 agtgccacat gcttgtgtgt agaggaggag gtggccctgc cggctccgcg 7450

 ctgctgtgcc tgtgatccct acctgctccc cgctcctgtt gccagcagca 7500

 ctcactgcac tcctttgtca tatactctgc atcactgtca tactcacaac 7550

 ttcgtgaata aagttgtgtg ctttattcgt c 7581

<210> 159
<211> 778
<212> PRT
<213> Homo sapien

<400> 159
 Met Pro Ala Phe Leu Gly Leu Lys Cys Leu Gly Lys Leu Cys Ser
   1               5                  10                  15

 Ser Glu Lys Ser Lys Val Thr Ser Ser Glu Arg Thr Ser Ala Arg
                  20                  25                  30

 Gly Ser Asn Arg Lys Arg Leu Ile Val Glu Asp Arg Arg Val Ser
                  35                  40                  45

 Gly Thr Ser Phe Thr Ala His Arg Arg Ala Thr Ile Thr His Leu
                  50                  55                  60

 Leu Tyr Leu Cys Pro Lys Asp Tyr Cys Pro Arg Gly Arg Val Cys
                  65                  70                  75

 Asn Ser Val Asp Pro Phe Val Ala His Pro Gln Asp Pro His His
                  80                  85                  90

 Pro Ser Glu Lys Pro Val Ile His Cys His Lys Cys Gly Glu Pro
                  95                 100                 105

 Cys Lys Gly Glu Val Leu Arg Val Gln Thr Lys His Phe His Ile
                 110                 115                 120

 Lys Cys Phe Thr Cys Lys Val Cys Gly Cys Asp Leu Ala Gln Gly
                 125                 130                 135

 Gly Phe Phe Ile Lys Asn Gly Glu Tyr Leu Cys Thr Leu Asp Tyr
                 140                 145                 150

 Gln Arg Met Tyr Gly Thr Arg Cys His Gly Cys Gly Glu Phe Val
                 155                 160                 165

 Glu Gly Glu Val Val Thr Ala Leu Gly Lys Thr Tyr His Pro Asn
                 170                 175                 180

 Cys Phe Ala Cys Thr Ile Cys Lys Arg Pro Phe Pro Pro Gly Asp
                 185                 190                 195

 Arg Val Thr Phe Asn Gly Arg Asp Cys Leu Cys Gln Leu Cys Ala
                 200                 205                 210

 Gln Pro Met Ser Ser Ser Pro Lys Glu Thr Thr Phe Ser Ser Asn
                 215                 220                 225

 Cys Ala Gly Cys Gly Arg Asp Ile Lys Asn Gly Gln Ala Leu Leu
                 230                 235                 240

 Ala Leu Asp Lys Gln Trp His Leu Gly Cys Phe Lys Cys Lys Ser
                 245                 250                 255

 Cys Gly Lys Val Leu Thr Gly Glu Tyr Ile Ser Lys Asp Gly Ala
                 260                 265                 270

 Pro Tyr Cys Glu Lys Asp Tyr Gln Gly Leu Phe Gly Val Lys Cys
                 275                 280                 285

 Glu Ala Cys His Gln Phe Ile Thr Gly Lys Val Leu Glu Ala Gly
                 290                 295                 300

 Asp Lys His Tyr His Pro Ser Cys Ala Arg Cys Ser Arg Cys Asn
                 305                 310                 315

 Gln Met Phe Thr Glu Gly Glu Glu Met Tyr Leu Gln Gly Ser Thr
                 320                 325                 330

 Val Trp His Pro Asp Cys Lys Gln Ser Thr Lys Thr Glu Glu Lys
                 335                 340                 345

 Leu Arg Pro Thr Arg Thr Ser Ser Glu Ser Ile Tyr Ser Arg Pro
                 350                 355                 360

 Gly Ser Ser Ile Pro Gly Ser Pro Gly His Thr Ile Tyr Ala Lys
                 365                 370                 375

 Val Asp Asn Glu Ile Leu Asp Tyr Lys Asp Leu Ala Ala Ile Pro
                 380                 385                 390

 Lys Val Lys Ala Ile Tyr Asp Ile Glu Arg Pro Asp Leu Ile Thr
                 395                 400                 405

 Tyr Glu Pro Phe Tyr Thr Ser Gly Tyr Asp Asp Lys Gln Glu Arg
                 410                 415                 420

 Gln Ser Leu Gly Glu Ser Pro Arg Thr Leu Ser Pro Thr Pro Ser
                 425                 430                 435

 Ala Glu Gly Tyr Gln Asp Val Arg Asp Arg Met Ile His Arg Ser
                 440                 445                 450

 Thr Ser Gln Gly Ser Ile Asn Ser Pro Val Tyr Ser Arg His Ser
                 455                 460                 465

 Tyr Thr Pro Thr Thr Ser Arg Ser Pro Gln His Phe His Arg Pro
                 470                 475                 480

 Gly Asn Glu Pro Ser Ser Gly Arg Asn Ser Pro Leu Pro Tyr Arg
                 485                 490                 495

 Pro Asp Ser Arg Pro Leu Thr Pro Thr Tyr Ala Gln Ala Pro Lys
                 500                 505                 510

 His Phe His Val Pro Asp Gln Gly Ile Asn Ile Tyr Arg Lys Pro
                 515                 520                 525

 Pro Ile Tyr Lys Gln His Ala Ala Leu Ala Ala Gln Ser Lys Ser
                 530                 535                 540

 Ser Glu Asp Ile Ile Lys Phe Ser Lys Phe Pro Ala Ala Gln Ala
                 545                 550                 555

 Pro Asp Pro Ser Glu Thr Pro Glu Ile Glu Thr Asp His Trp Pro
                 560                 565                 570

 Gly Pro Pro Ser Phe Ala Val Ile Gly Pro Asp Met Lys Arg Arg
                 575                 580                 585

 Ser Ser Gly Arg Glu Glu Asp Asp Glu Glu Leu Leu Arg Arg Arg
                 590                 595                 600

 Gln Leu Gln Glu Glu Gln Leu Met Lys Leu Asn Ser Gly Leu Gly
                 605                 610                 615

 Gln Leu Ile Leu Lys Glu Glu Met Glu Lys Glu Ser Arg Glu Arg
                 620                 625                 630

 Ser Ser Leu Leu Ala Ser Arg Tyr Asp Ser Pro Ile Asn Ser Ala
                 635                 640                 645

 Ser His Ile Pro Ser Ser Lys Thr Ala Ser Leu Pro Gly Tyr Gly
                 650                 655                 660

 Arg Asn Gly Leu His Arg Pro Val Ser Thr Asp Phe Ala Gln Tyr
                 665                 670                 675

 Asn Ser Tyr Gly Asp Val Ser Gly Gly Val Arg Asp Tyr Gln Thr
                 680                 685                 690

 Leu Pro Asp Gly His Met Pro Ala Met Arg Met Asp Arg Gly Val
                 695                 700                 705

 Ser Met Pro Asn Met Leu Glu Pro Lys Ile Phe Pro Tyr Glu Met
                 710                 715                 720

 Leu Met Val Thr Asn Arg Gly Arg Asn Lys Ile Leu Arg Glu Val
                 725                 730                 735

 Asp Arg Thr Arg Leu Glu Arg His Leu Ala Pro Glu Val Phe Arg
                 740                 745                 750

 Glu Ile Phe Gly Met Ser Ile Gln Glu Phe Asp Arg Leu Pro Leu
                 755                 760                 765

 Trp Arg Arg Asn Asp Met Lys Lys Lys Ala Lys Leu Phe
                 770                 775

<210> 160
<211> 1672
<212> DNA
<213> Homo sapien

<400> 160
 ggcttcatga cagaaagatg tgtgttctcg gactctgtgc tcttattgat 50

 atggaacaga taccccaagt tttaaatcag gtttctggac agattttgcc 100

 ggcttttatc cttttattta acggattgaa aagagcatat gcctgccatg 150

 cagaacatga gaatgacagt gatgatgatg atgaagctga agatgatgat 200

 gaaaccgagg aactggggag tgatgaagat gatattgatg aagatgggca 250

 agaatatttg gagattctgg ctaagcaggc tggtgaagat ggagatgatg 300

 aagattggga agaagatgat gctgaagaga ctgctctgga aggctattcc 350

 acaatcattg atgatgaaga taaccctgtt gatgagtatc agatatttaa 400

 agctatcttt caaactattc aaaatcgtaa tcctgtgtgg tatcaggcac 450

 tgactcacgg tcttaatgaa gaacaaagaa aacagttaca ggacatagca 500

 actctggctg atcaaagaag agcagcccat gaatccaaaa tgattgagaa 550

 gcatggagga tacaaattca gtgctccagt tgtgccaagt tctttcaatt 600

 ttggaggccc agcaccaggg atgaattgag ttatctcttt ctttcctgct 650

 gtgtgcttgt agtgaagagc ttgtgttcct cctagtagtg gttccagaac 700

 tggttcatgt tatctattct aaactaataa tcaatagatg gacaaaagaa 750

 acaacaaccc caggagatgg gacctgatca tgcaacctgg cactggaaaa 800

 gaaatcagcg ggattttggg ggtggggggg atgggaggta ccttagaggg 850

 agtattttct ttattttttg aagaaagtaa gatcctgact ctgaagcttc 900

 aaagtgacac tgtggaaatc tgaaacgagg ggatgtcatg aaggcagctt 950

 ttctttttct gaggaaaaaa taggcatggg ctacaggact atttaaaatg 1000

 tctcatttac agtataaaac tcaaaggtag atgtaatttt tacacctatg 1050

 agtatttgtc caatttctgt ctcttcctca ccattgggta tctattcttt 1100

 atatgtaaat aagataaggt catctgatag ccttattcag tcttcatcat 1150

 tttcatcatt gttcctatgt agattattgg acatttattg tagcactaca 1200

 taactgatta taaaaatctg taaatgaatt agcactttca tattgaaaca 1250

 agcctgctag cctatgtata aaatagcaaa atgtttgctg tttataaaaa 1300

 gatgtaatgg ggtggggggc aggggtaatt tcaagttatt aatttaaaaa 1350

 tgaactagca attttgtacc tggtgacttt gtggtgcact cacctctgat 1400

 agtgacttga attcggtatg taaaaagggg ttagtggtat ttcattgctg 1450

 ctaaaaatga caactccctc tgtgtcctgt ttttcttaaa gctgtcagtg 1500

 tacaagtggg tatttgaata ccagacctta ctgtaaaaaa taaaaaaggt 1550

 ggtatctaga gcatgtaaat tggatataaa gttctgctct taaagagttg 1600

 atctaagagt atggctaaac atctatatat gcaatctatt aaaagaactt 1650

 aattcggcta ttaaaaaaaa aa 1672

<210> 161
<211> 2913
<212> DNA
<213> Homo sapien

<400> 161
 gggggagccc ctgcaagttt cccgggccgc gcgccgcgct cgctcgcctc 50

 ccagcccgcg gcccgagccg ccgccgcgcc cgccatgccc tcggccaaac 100

 aaaggggctc caagggcggc cacggcgccg cgagcccctc ggagaagggt 150

 gcccacccgt cgggcggcgc ggatgacgtg gcgaagaagc cgccgccggc 200

 gccgcagcag ccgccgccgc cgcccgcgcc gcacccgcag cagcacccgc 250

 agcagcaccc gcagaaccag gcgcacggca agggcggcca ccgcggcggc 300

 ggcggcggcg gcggcaagtc ctcctcctcc tcctccgcct ccgccgccgc 350

 tgccgccgcc gccgcctcgt cctcggcgtc ctgctcgcgc aggctcggca 400

 gggcgctcaa ctttctcttc tacctcgccc tggtggcggc ggccgctttc 450

 tcgggctggt gcgtccacca cgtcctggag gaggtccagc aggtccggcg 500

 cagccaccag gacttctccc ggcagaggga ggagctgggc cagggcttgc 550

 agggcgtcga gcagaaggtg cagtctttgc aagccacatt tggaactttt 600

 gagtccatct tgagaagctc ccaacataaa caagacctca cagagaaagc 650

 tgtgaagcaa ggggagagtg aggtcagccg gatcagcgaa gtgctgcaga 700

 aactccagaa tgagattctc aaagacctct cggatgggat ccatgtggtg 750

 aaggacgccc gggagcggga cttcacgtcc ctggagaaca cggtggagga 800

 gcggctgacg gagctcacca aatccatcaa cgacaacatc gccatcttca 850

 cagaagtcca gaagaggagc cagaaggaga tcaatgacat gaaggcaaag 900

 gttgcctccc tggaagaatc tgaggggaac aagcaggatt tgaaagcctt 950

 aaaggaagct gtgaaggaga tacagacctc agccaagtcc agagagtggg 1000

 acatggaggc cctgagaagt acccttcaga ctatggagtc tgacatctac 1050

 accgaggttc gcgagctggt gagcctcaag caggagcagc aggctttcaa 1100

 ggaggcggcc gacacggagc ggctcgccct gcaggccctc acggagaagc 1150

 ttctcaggtc tgaggagtcc gtctcccgcc tcccggagga gatccggaga 1200

 ctggaggaag agctccgcca gctgaagtcc gattcccacg ggccgaagga 1250

 ggacggaggc ttcagacact cggaagcctt tgaggcactc cagcaaaaga 1300

 gtcagggact ggactccagg ctccagcacg tggaggatgg ggtgctctcc 1350

 atgcaggtgg cttctgcgcg ccagaccgag agcctggagt ccctcctgtc 1400

 caagagccag gagcacgagc agcgcctggc cgccctgcag gggcgcctgg 1450

 aaggcctcgg gtcctcagag gcagaccagg atggcctggc cagcacggtg 1500

 aggagcctgg gcgagaccca gctggtgctc tacggtgacg tggaggagct 1550

 gaagaggagt gtgggcgagc tccccagcac cgtggaatca ctccagaagg 1600

 tgcaggagca ggtgcacacg ctgctcagtc aggaccaagc ccaggccgcc 1650

 cgtctgcctc ctcaggactt cctggacaga ctttcttctc tagacaacct 1700

 gaaagcctca gtcagccaag tggaggcgga cttgaaaatg ctcaggactg 1750

 ctgtggacag tttggttgca tactcggtca aaatagaaac caacgagaac 1800

 aatctggaat cagccaaggg tttactagat gacctgagga atgatctgga 1850

 taggttgttt gtgaaagtgg agaagattca cgaaaaggtc taaatgaatt 1900

 gcgtgtgcag ggcgcggatt taaagtccaa tttctcatga ccaaaaaatg 1950

 tgtggttttt tcccatgtgt cccctacccc ccaatttctt gtcccctctt 2000

 aaagagcagt tgtcaccacc tgaacaccaa ggcattgtat tttcatgccc 2050

 agttaactta tttacaatat ttaagttctc tgcttctgca tttggttggt 2100

 ttcctgaagc gcagcccctg tgaataacag gtggcttttc atggatgtct 2150

 ctagtcagag aaaaatgata aaggcttaaa ttgaggatta acagaagcag 2200

 attaacctca gaaatcctgt ctggctggca gatttcaagt aaaaaaaaaa 2250

 aaaaggtggg ttggggggac ccttttcttt ctagttgtct ttaaggaaaa 2300

 ttaattttac tttttttttt gttctggccg aaatttttat gagatatctc 2350

 tcacttgtct tccactttga accggttaaa gctcatagct gtcagctctg 2400

 aatgaggagg ggagaagccc ctgggtcttt ctttgaaagg aatccgctgc 2450

 ttgagggctg cctccctcat ggtgtgcgtg tcgttctctt cctgacgcat 2500

 ctgtgatatc agaggtaact atgcaaagca tccaggcggt tctgaatgtg 2550

 aagcactaca cccagcagag tcccggtgcc ctctgtcccc actgccggcc 2600

 catgtcctct ctccggaggt caccaaggaa tgcacaggtt tcgactacca 2650

 gaaaggggag tccttgggtt ctttcaaaaa attcgtgagg agagctgtct 2700

 acagtggaat agggggtctc cctggggaat gcaggccaag tccttttatt 2750

 ttaacatgat gtccatgaag aggtttgccg tctgggcagc cctgtcggca 2800

 aggagcgtgc atactgcgtt tgtgtaattg tttgctgtat ctcccttccc 2850

 tctgagctgt attgttcttt aatggctgtc ttgcccttcc aaaaaaaatt 2900

 gaaaaaaaaa aaa 2913

<210> 162
<211> 602
<212> PRT
<213> Homo sapien

<400> 162
 Met Pro Ser Ala Lys Gln Arg Gly Ser Lys Gly Gly His Gly Ala
   1               5                  10                  15

 Ala Ser Pro Ser Glu Lys Gly Ala His Pro Ser Gly Gly Ala Asp
                  20                  25                  30

 Asp Val Ala Lys Lys Pro Pro Pro Ala Pro Gln Gln Pro Pro Pro
                  35                  40                  45

 Pro Pro Ala Pro His Pro Gln Gln His Pro Gln Gln His Pro Gln
                  50                  55                  60

 Asn Gln Ala His Gly Lys Gly Gly His Arg Gly Gly Gly Gly Gly
                  65                  70                  75

 Gly Gly Lys Ser Ser Ser Ser Ser Ser Ala Ser Ala Ala Ala Ala
                  80                  85                  90

 Ala Ala Ala Ala Ser Ser Ser Ala Ser Cys Ser Arg Arg Leu Gly
                  95                 100                 105

 Arg Ala Leu Asn Phe Leu Phe Tyr Leu Ala Leu Val Ala Ala Ala
                 110                 115                 120

 Ala Phe Ser Gly Trp Cys Val His His Val Leu Glu Glu Val Gln
                 125                 130                 135

 Gln Val Arg Arg Ser His Gln Asp Phe Ser Arg Gln Arg Glu Glu
                 140                 145                 150

 Leu Gly Gln Gly Leu Gln Gly Val Glu Gln Lys Val Gln Ser Leu
                 155                 160                 165

 Gln Ala Thr Phe Gly Thr Phe Glu Ser Ile Leu Arg Ser Ser Gln
                 170                 175                 180

 His Lys Gln Asp Leu Thr Glu Lys Ala Val Lys Gln Gly Glu Ser
                 185                 190                 195

 Glu Val Ser Arg Ile Ser Glu Val Leu Gln Lys Leu Gln Asn Glu
                 200                 205                 210

 Ile Leu Lys Asp Leu Ser Asp Gly Ile His Val Val Lys Asp Ala
                 215                 220                 225

 Arg Glu Arg Asp Phe Thr Ser Leu Glu Asn Thr Val Glu Glu Arg
                 230                 235                 240

 Leu Thr Glu Leu Thr Lys Ser Ile Asn Asp Asn Ile Ala Ile Phe
                 245                 250                 255

 Thr Glu Val Gln Lys Arg Ser Gln Lys Glu Ile Asn Asp Met Lys
                 260                 265                 270

 Ala Lys Val Ala Ser Leu Glu Glu Ser Glu Gly Asn Lys Gln Asp
                 275                 280                 285

 Leu Lys Ala Leu Lys Glu Ala Val Lys Glu Ile Gln Thr Ser Ala
                 290                 295                 300

 Lys Ser Arg Glu Trp Asp Met Glu Ala Leu Arg Ser Thr Leu Gln
                 305                 310                 315

 Thr Met Glu Ser Asp Ile Tyr Thr Glu Val Arg Glu Leu Val Ser
                 320                 325                 330

 Leu Lys Gln Glu Gln Gln Ala Phe Lys Glu Ala Ala Asp Thr Glu
                 335                 340                 345

 Arg Leu Ala Leu Gln Ala Leu Thr Glu Lys Leu Leu Arg Ser Glu
                 350                 355                 360

 Glu Ser Val Ser Arg Leu Pro Glu Glu Ile Arg Arg Leu Glu Glu
                 365                 370                 375

 Glu Leu Arg Gln Leu Lys Ser Asp Ser His Gly Pro Lys Glu Asp
                 380                 385                 390

 Gly Gly Phe Arg His Ser Glu Ala Phe Glu Ala Leu Gln Gln Lys
                 395                 400                 405

 Ser Gln Gly Leu Asp Ser Arg Leu Gln His Val Glu Asp Gly Val
                 410                 415                 420

 Leu Ser Met Gln Val Ala Ser Ala Arg Gln Thr Glu Ser Leu Glu
                 425                 430                 435

 Ser Leu Leu Ser Lys Ser Gln Glu His Glu Gln Arg Leu Ala Ala
                 440                 445                 450

 Leu Gln Gly Arg Leu Glu Gly Leu Gly Ser Ser Glu Ala Asp Gln
                 455                 460                 465

 Asp Gly Leu Ala Ser Thr Val Arg Ser Leu Gly Glu Thr Gln Leu
                 470                 475                 480

 Val Leu Tyr Gly Asp Val Glu Glu Leu Lys Arg Ser Val Gly Glu
                 485                 490                 495

 Leu Pro Ser Thr Val Glu Ser Leu Gln Lys Val Gln Glu Gln Val
                 500                 505                 510

 His Thr Leu Leu Ser Gln Asp Gln Ala Gln Ala Ala Arg Leu Pro
                 515                 520                 525

 Pro Gln Asp Phe Leu Asp Arg Leu Ser Ser Leu Asp Asn Leu Lys
                 530                 535                 540

 Ala Ser Val Ser Gln Val Glu Ala Asp Leu Lys Met Leu Arg Thr
                 545                 550                 555

 Ala Val Asp Ser Leu Val Ala Tyr Ser Val Lys Ile Glu Thr Asn
                 560                 565                 570

 Glu Asn Asn Leu Glu Ser Ala Lys Gly Leu Leu Asp Asp Leu Arg
                 575                 580                 585

 Asn Asp Leu Asp Arg Leu Phe Val Lys Val Glu Lys Ile His Glu
                 590                 595                 600

 Lys Val


<210> 163
<211> 2913
<212> DNA
<213> Homo sapien

<400> 163
 gggggagccc ctgcaagttt cccgggccgc gcgccgcgct cgctcgcctc 50

 ccagcccgcg gcccgagccg ccgccgcgcc cgccatgccc tcggccaaac 100

 aaaggggctc caagggcggc cacggcgccg cgagcccctc ggagaagggt 150

 gcccacccgt cgggcggcgc ggatgacgtg gcgaagaagc cgccgccggc 200

 gccgcagcag ccgccgccgc cgcccgcgcc gcacccgcag cagcacccgc 250

 agcagcaccc gcagaaccag gcgcacggca agggcggcca ccgcggcggc 300

 ggcggcggcg gcggcaagtc ctcctcctcc tcctccgcct ccgccgccgc 350

 tgccgccgcc gccgcctcgt cctcggcgtc ctgctcgcgc aggctcggca 400

 gggcgctcaa ctttctcttc tacctcgccc tggtggcggc ggccgctttc 450

 tcgggctggt gcgtccacca cgtcctggag gaggtccagc aggtccggcg 500

 cagccaccag gacttctccc ggcagaggga ggagctgggc cagggcttgc 550

 agggcgtcga gcagaaggtg cagtctttgc aagccacatt tggaactttt 600

 gagtccatct tgagaagctc ccaacataaa caagacctca cagagaaagc 650

 tgtgaagcaa ggggagagtg aggtcagccg gatcagcgaa gtgctgcaga 700

 aactccagaa tgagattctc aaagacctct cggatgggat ccatgtggtg 750

 aaggacgccc gggagcggga cttcacgtcc ctggagaaca cggtggagga 800

 gcggctgacg gagctcacca aatccatcaa cgacaacatc gccatcttca 850

 cagaagtcca gaagaggagc cagaaggaga tcaatgacat gaaggcaaag 900

 gttgcctccc tggaagaatc tgaggggaac aagcaggatt tgaaagcctt 950

 aaaggaagct gtgaaggaga tacagacctc agccaagtcc agagagtggg 1000

 acatggaggc cctgagaagt acccttcaga ctatggagtc tgacatctac 1050

 accgaggttc gcgagctggt gagcctcaag caggagcagc aggctttcaa 1100

 ggaggcggcc gacacggagc ggctcgccct gcaggccctc acggagaagc 1150

 ttctcaggtc tgaggagtcc gtctcccgcc tcccggagga gatccggaga 1200

 ctggaggaag agctccgcca gctgaagtcc gattcccacg ggccgaagga 1250

 ggacggaggc ttcagacact cggaagcctt tgaggcactc cagcaaaaga 1300

 gtcagggact ggactccagg ctccagcacg tggaggatgg ggtgctctcc 1350

 atgcaggtgg cttctgcgcg ccagaccgag agcctggagt ccctcctgtc 1400

 caagagccag gagcacgagc agcgcctggc cgccctgcag gggcgcctgg 1450

 aaggcctcgg gtcctcagag gcagaccagg atggcctggc cagcacggtg 1500

 aggagcctgg gcgagaccca gctggtgctc tacggtgacg tggaggagct 1550

 gaagaggagt gtgggcgagc tccccagcac cgtggaatca ctccagaagg 1600

 tgcaggagca ggtgcacacg ctgctcagtc aggaccaagc ccaggccgcc 1650

 cgtctgcctc ctcaggactt cctggacaga ctttcttctc tagacaacct 1700

 gaaagcctca gtcagccaag tggaggcgga cttgaaaatg ctcaggactg 1750

 ctgtggacag tttggttgca tactcggtca aaatagaaac caacgagaac 1800

 aatctggaat cagccaaggg tttactagat gacctgagga atgatctgga 1850

 taggttgttt gtgaaagtgg agaagattca cgaaaaggtc taaatgaatt 1900

 gcgtgtgcag ggcgcggatt taaagtccaa tttctcatga ccaaaaaatg 1950

 tgtggttttt tcccatgtgt cccctacccc ccaatttctt gtcccctctt 2000

 aaagagcagt tgtcaccacc tgaacaccaa ggcattgtat tttcatgccc 2050

 agttaactta tttacaatat ttaagttctc tgcttctgca tttggttggt 2100

 ttcctgaagc gcagcccctg tgaataacag gtggcttttc atggatgtct 2150

 ctagtcagag aaaaatgata aaggcttaaa ttgaggatta acagaagcag 2200

 attaacctca gaaatcctgt ctggctggca gatttcaagt aaaaaaaaaa 2250

 aaaaggtggg ttggggggac ccttttcttt ctagttgtct ttaaggaaaa 2300

 ttaattttac tttttttttt gttctggccg aaatttttat gagatatctc 2350

 tcacttgtct tccactttga accggttaaa gctcatagct gtcagctctg 2400

 aatgaggagg ggagaagccc ctgggtcttt ctttgaaagg aatccgctgc 2450

 ttgagggctg cctccctcat ggtgtgcgtg tcgttctctt cctgacgcat 2500

 ctgtgatatc agaggtaact atgcaaagca tccaggcggt tctgaatgtg 2550

 aagcactaca cccagcagag tcccggtgcc ctctgtcccc actgccggcc 2600

 catgtcctct ctccggaggt caccaaggaa tgcacaggtt tcgactacca 2650

 gaaaggggag tccttgggtt ctttcaaaaa attcgtgagg agagctgtct 2700

 acagtggaat agggggtctc cctggggaat gcaggccaag tccttttatt 2750

 ttaacatgat gtccatgaag aggtttgccg tctgggcagc cctgtcggca 2800

 aggagcgtgc atactgcgtt tgtgtaattg tttgctgtat ctcccttccc 2850

 tctgagctgt attgttcttt aatggctgtc ttgcccttcc aaaaaaaatt 2900

 gaaaaaaaaa aaa 2913

<210> 164
<211> 602
<212> PRT
<213> Homo sapien

<400> 164
 Met Pro Ser Ala Lys Gln Arg Gly Ser Lys Gly Gly His Gly Ala
   1               5                  10                  15

 Ala Ser Pro Ser Glu Lys Gly Ala His Pro Ser Gly Gly Ala Asp
                  20                  25                  30

 Asp Val Ala Lys Lys Pro Pro Pro Ala Pro Gln Gln Pro Pro Pro
                  35                  40                  45

 Pro Pro Ala Pro His Pro Gln Gln His Pro Gln Gln His Pro Gln
                  50                  55                  60

 Asn Gln Ala His Gly Lys Gly Gly His Arg Gly Gly Gly Gly Gly
                  65                  70                  75

 Gly Gly Lys Ser Ser Ser Ser Ser Ser Ala Ser Ala Ala Ala Ala
                  80                  85                  90

 Ala Ala Ala Ala Ser Ser Ser Ala Ser Cys Ser Arg Arg Leu Gly
                  95                 100                 105

 Arg Ala Leu Asn Phe Leu Phe Tyr Leu Ala Leu Val Ala Ala Ala
                 110                 115                 120

 Ala Phe Ser Gly Trp Cys Val His His Val Leu Glu Glu Val Gln
                 125                 130                 135

 Gln Val Arg Arg Ser His Gln Asp Phe Ser Arg Gln Arg Glu Glu
                 140                 145                 150

 Leu Gly Gln Gly Leu Gln Gly Val Glu Gln Lys Val Gln Ser Leu
                 155                 160                 165

 Gln Ala Thr Phe Gly Thr Phe Glu Ser Ile Leu Arg Ser Ser Gln
                 170                 175                 180

 His Lys Gln Asp Leu Thr Glu Lys Ala Val Lys Gln Gly Glu Ser
                 185                 190                 195

 Glu Val Ser Arg Ile Ser Glu Val Leu Gln Lys Leu Gln Asn Glu
                 200                 205                 210

 Ile Leu Lys Asp Leu Ser Asp Gly Ile His Val Val Lys Asp Ala
                 215                 220                 225

 Arg Glu Arg Asp Phe Thr Ser Leu Glu Asn Thr Val Glu Glu Arg
                 230                 235                 240

 Leu Thr Glu Leu Thr Lys Ser Ile Asn Asp Asn Ile Ala Ile Phe
                 245                 250                 255

 Thr Glu Val Gln Lys Arg Ser Gln Lys Glu Ile Asn Asp Met Lys
                 260                 265                 270

 Ala Lys Val Ala Ser Leu Glu Glu Ser Glu Gly Asn Lys Gln Asp
                 275                 280                 285

 Leu Lys Ala Leu Lys Glu Ala Val Lys Glu Ile Gln Thr Ser Ala
                 290                 295                 300

 Lys Ser Arg Glu Trp Asp Met Glu Ala Leu Arg Ser Thr Leu Gln
                 305                 310                 315

 Thr Met Glu Ser Asp Ile Tyr Thr Glu Val Arg Glu Leu Val Ser
                 320                 325                 330

 Leu Lys Gln Glu Gln Gln Ala Phe Lys Glu Ala Ala Asp Thr Glu
                 335                 340                 345

 Arg Leu Ala Leu Gln Ala Leu Thr Glu Lys Leu Leu Arg Ser Glu
                 350                 355                 360

 Glu Ser Val Ser Arg Leu Pro Glu Glu Ile Arg Arg Leu Glu Glu
                 365                 370                 375

 Glu Leu Arg Gln Leu Lys Ser Asp Ser His Gly Pro Lys Glu Asp
                 380                 385                 390

 Gly Gly Phe Arg His Ser Glu Ala Phe Glu Ala Leu Gln Gln Lys
                 395                 400                 405

 Ser Gln Gly Leu Asp Ser Arg Leu Gln His Val Glu Asp Gly Val
                 410                 415                 420

 Leu Ser Met Gln Val Ala Ser Ala Arg Gln Thr Glu Ser Leu Glu
                 425                 430                 435

 Ser Leu Leu Ser Lys Ser Gln Glu His Glu Gln Arg Leu Ala Ala
                 440                 445                 450

 Leu Gln Gly Arg Leu Glu Gly Leu Gly Ser Ser Glu Ala Asp Gln
                 455                 460                 465

 Asp Gly Leu Ala Ser Thr Val Arg Ser Leu Gly Glu Thr Gln Leu
                 470                 475                 480

 Val Leu Tyr Gly Asp Val Glu Glu Leu Lys Arg Ser Val Gly Glu
                 485                 490                 495

 Leu Pro Ser Thr Val Glu Ser Leu Gln Lys Val Gln Glu Gln Val
                 500                 505                 510

 His Thr Leu Leu Ser Gln Asp Gln Ala Gln Ala Ala Arg Leu Pro
                 515                 520                 525

 Pro Gln Asp Phe Leu Asp Arg Leu Ser Ser Leu Asp Asn Leu Lys
                 530                 535                 540

 Ala Ser Val Ser Gln Val Glu Ala Asp Leu Lys Met Leu Arg Thr
                 545                 550                 555

 Ala Val Asp Ser Leu Val Ala Tyr Ser Val Lys Ile Glu Thr Asn
                 560                 565                 570

 Glu Asn Asn Leu Glu Ser Ala Lys Gly Leu Leu Asp Asp Leu Arg
                 575                 580                 585

 Asn Asp Leu Asp Arg Leu Phe Val Lys Val Glu Lys Ile His Glu
                 590                 595                 600

 Lys Val


<210> 165
<211> 3344
<212> DNA
<213> Homo sapien

<400> 165
 ggtacagctg cgcgtctgcg ggaataggtg cagcgggccc ttggcggggg 50

 actctgaggg aggagctggg gacggcgacc ctaggagagt tctttggggt 100

 gactttcaag atggactcta ctctaacagc aagtgaaatc cggcagcgat 150

 ttatagattt cttcaagagg aacgagcata cgtatgttca ctcgtctgcc 200

 accatcccat tggatgaccc cactttgctc tttgccaatg caggcatgaa 250

 ccagtttaaa cccattttcc tgaacacaat tgacccatct caccccatgg 300

 caaagctgag cagagctgcc aatacccaga agtgcatccg ggctgggggc 350

 aaacaaaatg acctggacga tgtgggcaag gatgtctatc atcacacctt 400

 cttcgagatg ctgggctctt ggtcttttgg agattacttt aaggaattgg 450

 catgtaagat ggctctggaa ctcctcaccc aagagtttgg cattcccatt 500

 gaaagacttt atgttactta ctttggcggg gatgaagcag ctggcttaga 550

 agcagatctg gaatgcaaac agatctggca aaatttgggg ctggatgaca 600

 ccaaaatcct cccaggcaac atgaaggata acttctggga gatgggtgac 650

 acgggcccct gtggtccttg cagtgagatc cactacgacc ggattggtgg 700

 tcgggacgcc gcacatcttg tcaaccagga cgaccctaat gtgctggaga 750

 tctggaacct tgtgttcatc cagtataaca gggaagctga tggcattctg 800

 aaacctcttc ccaagaaaag cattgacaca gggatgggcc tggaacgact 850

 ggtatctgtg ctgcagaata agatgtccaa ctatgacact gacctttttg 900

 tcccttactt tgaagccatt cagaagggca caggtgcccg accatacact 950

 gggaaagttg gtgctgagga tgccgatggg attgacatgg cctaccgggt 1000

 gctggctgac catgctcgga ccatcactgt ggcactggct gatggtggcc 1050

 ggcctgacaa cacagggcgt ggatatgtgt tgagacggat tctccgccga 1100

 gctgtccgat acgcccatga aaagctcaat gccagcaggg gcttctttgc 1150

 tacgttagtg gatgttgtcg tccagtccct gggagatgca tttcctgagc 1200

 tgaagaagga cccagacatg gtgaaggaca tcattaatga agaagaggtg 1250

 cagtttctca agactctcag cagagggcgt cgcatcctgg acaggaaaat 1300

 tcagagcctg ggagacagca agaccattcc cggagacact gcttggctcc 1350

 tctatgacac ctatgggttt ccagtggatc tgactggact gattgctgaa 1400

 gagaagggcc tggtggtaga catggatggc tttgaagagg agaggaaact 1450

 ggcccagctg aaatcacagg gcaagggagc tggtggggaa gacctcatta 1500

 tgctggacat ttacgctatc gaagagctcc gggcacgggg tctggaggtc 1550

 acagatgatt ccccaaagta caattaccat ttggactcca gtggtagcta 1600

 tgtatttgag aacacagtgg ctacggtgat ggctctgcgc agggagaaga 1650

 tgttcgtgga agaggtgtcc acaggccagg agtgtggagt ggtgctggac 1700

 aagacctgtt tctatgctga gcaaggaggc cagatctatg acgaaggcta 1750

 cctggtgaag gtggatgaca gcagtgaaga taaaacagag tttacagtga 1800

 agaatgctca ggtccgagga gggtatgtgc tacacattgg aaccatctac 1850

 ggtgacctga aagtggggga tcaggtctgg ctgtttattg atgagccccg 1900

 acgaagaccc atcatgagca accacacagc tacgcacatt ctgaacttcg 1950

 ccctgcgctc agtgcttggg gaagctgacc agaaaggctc attggttgct 2000

 cctgaccgcc tcagatttga ctttactgcc aagggagcca tgtccaccca 2050

 acagatcaag aaggctgaag agattgctaa tgagatgatt gaggcagcca 2100

 aggccgtcta tacccaggat tgccccctgg cagcagcgaa agccatccag 2150

 ggcctacggg ctgtgtttga tgagacctat cctgaccctg tgcgagtcgt 2200

 ctccattggg gtcccggtgt ccgagttgct ggatgacccc tctgggcctg 2250

 ctggctccct gacttctgtt gagttctgtg ggggaacgca cctgcggaac 2300

 tcgagtcatg caggagcttt tgtgatcgtg acggaagaag ccattgccaa 2350

 gggtatccgg aggattgtgg ctgtcacagg tgccgaggcc cagaaggccc 2400

 tcaggaaagc agagagcttg aagaaatgtc tctctgtcat ggaagccaaa 2450

 gtgaaggctc agactgctcc aaacaaggat gtgcagaggg agatcgctga 2500

 ccttggagag gccctggcca ctgcagtcat cccccagtgg cagaaggatg 2550

 aattgcggga gactctcaaa tccctaaaga aggtcatgga tgacttggac 2600

 cgagccagca aagccgatgt ccagaaacga gtgttagaga agacgaagca 2650

 gttcatcgac agcaacccca accagcctct tgtcatcctg gagatggaga 2700

 gcggcgcctc agccaaggcc ctgaatgaag ccttgaagct cttcaagatg 2750

 cactcccctc agacttctgc catgctcttc acggtggaca atgaggctgg 2800

 caagatcacg tgcctgtgtc aagtccccca gaatgcagcc aatcggggct 2850

 taaaagccag cgagtgggtg cagcaggtgt caggcttgat ggacggtaaa 2900

 ggtggtggca aggatgtgtc tgcacaggcc acaggcaaga acgttggctg 2950

 cctgcaggag gcgctgcagc tggccacttc cttcgcccag ctgcgcctcg 3000

 gggatgtaaa gaactgagtg gggaaggagg aggctcccac tggatccatc 3050

 cgtccagcca agagctcttc atctgctaca agaacatttg aatcttggga 3100

 cctttaaaga gcccctccta acccagcagt aactggaaca cacttgggag 3150

 cagtcctatg tctcagtgcc ccttaaattt ctgccctgag ccctccacgt 3200

 cagtgccatc ggtctagaac cactaacccc gcattgctgt tgatcgtcac 3250

 gctcgcatct atagataacg gctctccaga cctgagcttt ccgcgtcagc 3300

 aagtaggaat cgtttttgct gcagagaata aaaggaccac gtgc 3344

<210> 166
<211> 968
<212> PRT
<213> Homo sapien

<400> 166
 Met Asp Ser Thr Leu Thr Ala Ser Glu Ile Arg Gln Arg Phe Ile
   1               5                  10                  15

 Asp Phe Phe Lys Arg Asn Glu His Thr Tyr Val His Ser Ser Ala
                  20                  25                  30

 Thr Ile Pro Leu Asp Asp Pro Thr Leu Leu Phe Ala Asn Ala Gly
                  35                  40                  45

 Met Asn Gln Phe Lys Pro Ile Phe Leu Asn Thr Ile Asp Pro Ser
                  50                  55                  60

 His Pro Met Ala Lys Leu Ser Arg Ala Ala Asn Thr Gln Lys Cys
                  65                  70                  75

 Ile Arg Ala Gly Gly Lys Gln Asn Asp Leu Asp Asp Val Gly Lys
                  80                  85                  90

 Asp Val Tyr His His Thr Phe Phe Glu Met Leu Gly Ser Trp Ser
                  95                 100                 105

 Phe Gly Asp Tyr Phe Lys Glu Leu Ala Cys Lys Met Ala Leu Glu
                 110                 115                 120

 Leu Leu Thr Gln Glu Phe Gly Ile Pro Ile Glu Arg Leu Tyr Val
                 125                 130                 135

 Thr Tyr Phe Gly Gly Asp Glu Ala Ala Gly Leu Glu Ala Asp Leu
                 140                 145                 150

 Glu Cys Lys Gln Ile Trp Gln Asn Leu Gly Leu Asp Asp Thr Lys
                 155                 160                 165

 Ile Leu Pro Gly Asn Met Lys Asp Asn Phe Trp Glu Met Gly Asp
                 170                 175                 180

 Thr Gly Pro Cys Gly Pro Cys Ser Glu Ile His Tyr Asp Arg Ile
                 185                 190                 195

 Gly Gly Arg Asp Ala Ala His Leu Val Asn Gln Asp Asp Pro Asn
                 200                 205                 210

 Val Leu Glu Ile Trp Asn Leu Val Phe Ile Gln Tyr Asn Arg Glu
                 215                 220                 225

 Ala Asp Gly Ile Leu Lys Pro Leu Pro Lys Lys Ser Ile Asp Thr
                 230                 235                 240

 Gly Met Gly Leu Glu Arg Leu Val Ser Val Leu Gln Asn Lys Met
                 245                 250                 255

 Ser Asn Tyr Asp Thr Asp Leu Phe Val Pro Tyr Phe Glu Ala Ile
                 260                 265                 270

 Gln Lys Gly Thr Gly Ala Arg Pro Tyr Thr Gly Lys Val Gly Ala
                 275                 280                 285

 Glu Asp Ala Asp Gly Ile Asp Met Ala Tyr Arg Val Leu Ala Asp
                 290                 295                 300

 His Ala Arg Thr Ile Thr Val Ala Leu Ala Asp Gly Gly Arg Pro
                 305                 310                 315

 Asp Asn Thr Gly Arg Gly Tyr Val Leu Arg Arg Ile Leu Arg Arg
                 320                 325                 330

 Ala Val Arg Tyr Ala His Glu Lys Leu Asn Ala Ser Arg Gly Phe
                 335                 340                 345

 Phe Ala Thr Leu Val Asp Val Val Val Gln Ser Leu Gly Asp Ala
                 350                 355                 360

 Phe Pro Glu Leu Lys Lys Asp Pro Asp Met Val Lys Asp Ile Ile
                 365                 370                 375

 Asn Glu Glu Glu Val Gln Phe Leu Lys Thr Leu Ser Arg Gly Arg
                 380                 385                 390

 Arg Ile Leu Asp Arg Lys Ile Gln Ser Leu Gly Asp Ser Lys Thr
                 395                 400                 405

 Ile Pro Gly Asp Thr Ala Trp Leu Leu Tyr Asp Thr Tyr Gly Phe
                 410                 415                 420

 Pro Val Asp Leu Thr Gly Leu Ile Ala Glu Glu Lys Gly Leu Val
                 425                 430                 435

 Val Asp Met Asp Gly Phe Glu Glu Glu Arg Lys Leu Ala Gln Leu
                 440                 445                 450

 Lys Ser Gln Gly Lys Gly Ala Gly Gly Glu Asp Leu Ile Met Leu
                 455                 460                 465

 Asp Ile Tyr Ala Ile Glu Glu Leu Arg Ala Arg Gly Leu Glu Val
                 470                 475                 480

 Thr Asp Asp Ser Pro Lys Tyr Asn Tyr His Leu Asp Ser Ser Gly
                 485                 490                 495

 Ser Tyr Val Phe Glu Asn Thr Val Ala Thr Val Met Ala Leu Arg
                 500                 505                 510

 Arg Glu Lys Met Phe Val Glu Glu Val Ser Thr Gly Gln Glu Cys
                 515                 520                 525

 Gly Val Val Leu Asp Lys Thr Cys Phe Tyr Ala Glu Gln Gly Gly
                 530                 535                 540

 Gln Ile Tyr Asp Glu Gly Tyr Leu Val Lys Val Asp Asp Ser Ser
                 545                 550                 555

 Glu Asp Lys Thr Glu Phe Thr Val Lys Asn Ala Gln Val Arg Gly
                 560                 565                 570

 Gly Tyr Val Leu His Ile Gly Thr Ile Tyr Gly Asp Leu Lys Val
                 575                 580                 585

 Gly Asp Gln Val Trp Leu Phe Ile Asp Glu Pro Arg Arg Arg Pro
                 590                 595                 600

 Ile Met Ser Asn His Thr Ala Thr His Ile Leu Asn Phe Ala Leu
                 605                 610                 615

 Arg Ser Val Leu Gly Glu Ala Asp Gln Lys Gly Ser Leu Val Ala
                 620                 625                 630

 Pro Asp Arg Leu Arg Phe Asp Phe Thr Ala Lys Gly Ala Met Ser
                 635                 640                 645

 Thr Gln Gln Ile Lys Lys Ala Glu Glu Ile Ala Asn Glu Met Ile
                 650                 655                 660

 Glu Ala Ala Lys Ala Val Tyr Thr Gln Asp Cys Pro Leu Ala Ala
                 665                 670                 675

 Ala Lys Ala Ile Gln Gly Leu Arg Ala Val Phe Asp Glu Thr Tyr
                 680                 685                 690

 Pro Asp Pro Val Arg Val Val Ser Ile Gly Val Pro Val Ser Glu
                 695                 700                 705

 Leu Leu Asp Asp Pro Ser Gly Pro Ala Gly Ser Leu Thr Ser Val
                 710                 715                 720

 Glu Phe Cys Gly Gly Thr His Leu Arg Asn Ser Ser His Ala Gly
                 725                 730                 735

 Ala Phe Val Ile Val Thr Glu Glu Ala Ile Ala Lys Gly Ile Arg
                 740                 745                 750

 Arg Ile Val Ala Val Thr Gly Ala Glu Ala Gln Lys Ala Leu Arg
                 755                 760                 765

 Lys Ala Glu Ser Leu Lys Lys Cys Leu Ser Val Met Glu Ala Lys
                 770                 775                 780

 Val Lys Ala Gln Thr Ala Pro Asn Lys Asp Val Gln Arg Glu Ile
                 785                 790                 795

 Ala Asp Leu Gly Glu Ala Leu Ala Thr Ala Val Ile Pro Gln Trp
                 800                 805                 810

 Gln Lys Asp Glu Leu Arg Glu Thr Leu Lys Ser Leu Lys Lys Val
                 815                 820                 825

 Met Asp Asp Leu Asp Arg Ala Ser Lys Ala Asp Val Gln Lys Arg
                 830                 835                 840

 Val Leu Glu Lys Thr Lys Gln Phe Ile Asp Ser Asn Pro Asn Gln
                 845                 850                 855

 Pro Leu Val Ile Leu Glu Met Glu Ser Gly Ala Ser Ala Lys Ala
                 860                 865                 870

 Leu Asn Glu Ala Leu Lys Leu Phe Lys Met His Ser Pro Gln Thr
                 875                 880                 885

 Ser Ala Met Leu Phe Thr Val Asp Asn Glu Ala Gly Lys Ile Thr
                 890                 895                 900

 Cys Leu Cys Gln Val Pro Gln Asn Ala Ala Asn Arg Gly Leu Lys
                 905                 910                 915

 Ala Ser Glu Trp Val Gln Gln Val Ser Gly Leu Met Asp Gly Lys
                 920                 925                 930

 Gly Gly Gly Lys Asp Val Ser Ala Gln Ala Thr Gly Lys Asn Val
                 935                 940                 945

 Gly Cys Leu Gln Glu Ala Leu Gln Leu Ala Thr Ser Phe Ala Gln
                 950                 955                 960

 Leu Arg Leu Gly Asp Val Lys Asn
                 965

<210> 167
<211> 1246
<212> DNA
<213> Homo sapien

<400> 167
 gaccagccta cagccgcctg catctgtatc cagcgccagg tcccgccagt 50

 cccagctgcg cgcgcccccc agtcccgcac ccgttcggcc caggctaagt 100

 tagccctcac catgccggtc aaaggaggca ccaagtgcat caaatacctg 150

 ctgttcggat ttaacttcat cttctggctt gccgggattg ctgtccttgc 200

 cattggacta tggctccgat tcgactctca gaccaagagc atcttcgagc 250

 aagaaactaa taataataat tccagcttct acacaggagt ctatattctg 300

 atcggagccg gcgccctcat gatgctggtg ggcttcctgg gctgctgcgg 350

 ggctgtgcag gagtcccagt gcatgctggg actgttcttc ggcttcctct 400

 tggtgatatt cgccattgaa atagctgcgg ccatctgggg atattcccac 450

 aaggatgagg tgattaagga agtccaggag ttttacaagg acacctacaa 500

 caagctgaaa accaaggatg agccccagcg ggaaacgctg aaagccatcc 550

 actatgcgtt gaactgctgt ggtttggctg ggggcgtgga acagtttatc 600

 tcagacatct gccccaagaa ggacgtactc gaaaccttca ccgtgaagtc 650

 ctgtcctgat gccatcaaag aggtcttcga caataaattc cacatcatcg 700

 gcgcagtggg catcggcatt gccgtggtca tgatatttgg catgatcttc 750

 agtatgatct tgtgctgtgc tatccgcagg aaccgcgaga tggtctagag 800

 tcagcttaca tccctgagca ggaaagttta cccatgaaga ttggtgggat 850

 tttttgtttg tttgttttgt tttgtttgtt gtttgttgtt tgtttttttg 900

 ccactaattt tagtattcat tctgcattgc tagataaaag ctgaagttac 950

 tttatgtttg tcttttaatg cttcattcaa tattgacatt tgtagttgag 1000

 cggggggttt ggtttgcttt ggtttatatt ttttcagttg tttgtttttg 1050

 cttgttatat taagcagaaa tcctgcaatg aaaggtacta tatttgctag 1100

 actctagaca agatattgta cataaaagaa tttttttgtc tttaaataga 1150

 tacaaatgtc tatcaacttt aatcaagttg taacttatat tgaagacaat 1200

 ttgatacata ataaaaaatt atgacaatgt caaaaaaaaa aaaaaa 1246

<210> 168
<211> 228
<212> PRT
<213> Homo sapien

<400> 168
 Met Pro Val Lys Gly Gly Thr Lys Cys Ile Lys Tyr Leu Leu Phe
   1               5                  10                  15

 Gly Phe Asn Phe Ile Phe Trp Leu Ala Gly Ile Ala Val Leu Ala
                  20                  25                  30

 Ile Gly Leu Trp Leu Arg Phe Asp Ser Gln Thr Lys Ser Ile Phe
                  35                  40                  45

 Glu Gln Glu Thr Asn Asn Asn Asn Ser Ser Phe Tyr Thr Gly Val
                  50                  55                  60

 Tyr Ile Leu Ile Gly Ala Gly Ala Leu Met Met Leu Val Gly Phe
                  65                  70                  75

 Leu Gly Cys Cys Gly Ala Val Gln Glu Ser Gln Cys Met Leu Gly
                  80                  85                  90

 Leu Phe Phe Gly Phe Leu Leu Val Ile Phe Ala Ile Glu Ile Ala
                  95                 100                 105

 Ala Ala Ile Trp Gly Tyr Ser His Lys Asp Glu Val Ile Lys Glu
                 110                 115                 120

 Val Gln Glu Phe Tyr Lys Asp Thr Tyr Asn Lys Leu Lys Thr Lys
                 125                 130                 135

 Asp Glu Pro Gln Arg Glu Thr Leu Lys Ala Ile His Tyr Ala Leu
                 140                 145                 150

 Asn Cys Cys Gly Leu Ala Gly Gly Val Glu Gln Phe Ile Ser Asp
                 155                 160                 165

 Ile Cys Pro Lys Lys Asp Val Leu Glu Thr Phe Thr Val Lys Ser
                 170                 175                 180

 Cys Pro Asp Ala Ile Lys Glu Val Phe Asp Asn Lys Phe His Ile
                 185                 190                 195

 Ile Gly Ala Val Gly Ile Gly Ile Ala Val Val Met Ile Phe Gly
                 200                 205                 210

 Met Ile Phe Ser Met Ile Leu Cys Cys Ala Ile Arg Arg Asn Arg
                 215                 220                 225

 Glu Met Val


<210> 169
<211> 2704
<212> DNA
<213> Homo sapien

<400> 169
 gcttagtgta accagcggcg tatatttttt aggcgccttt tcgaaaacct 50

 agtagttaat attcatttgt ttaaatctta ttttattttt aagctcaaac 100

 tgcttaagaa taccttaatt ccttaaagtg aaataatttt ttgcaaaggg 150

 gtttcctcga tttggagctt tttttttctt ccaccgtcat ttctaactct 200

 taaaaccaac tcagttccat catggtgatg ttcaagaaga tcaagtcttt 250

 tgaggtggtc tttaacgacc ctgaaaaggt gtacggcagt ggcgagaggg 300

 tggctggccg ggtgatagtg gaggtgtgtg aagttactcg tgtcaaagcc 350

 gttaggatcc tggcttgcgg agtggctaaa gtgctttgga tgcagggatc 400

 ccagcagtgc aaacagactt cggagtacct gcgctatgaa gacacgcttc 450

 ttctggaaga ccagccaaca ggtgagaatg agatggtgat catgagacct 500

 ggaaacaaat atgagtacaa gttcggcttt gagcttcctc aggggcctct 550

 gggaacatcc ttcaaaggaa aatatgggtg tgtagactac tgggtgaagg 600

 cttttcttga ccgcccgagc cagccaactc aagagacaaa gaaaaacttt 650

 gaagtagtgg atctggtgga tgtcaatacc cctgatttaa tggcacctgt 700

 gtctgctaaa aaagaaaaga aagtttcctg catgttcatt cctgatgggc 750

 gggtgtctgt ctctgctcga attgacagaa aaggattctg tgaaggtgat 800

 gagatttcca tccatgctga ctttgagaat acatgttccc gaattgtggt 850

 ccccaaagct gccattgtgg cccgccacac ttaccttgcc aatggccaga 900

 ccaaggtgct gactcagaag ttgtcatcag tcagaggcaa tcatattatc 950

 tcagggacat gcgcatcatg gcgtggcaag agccttcggg ttcagaagat 1000

 caggccttct atcctgggct gcaacatcct tcgagttgaa tattccttac 1050

 tgatctatgt tagcgttcct ggatccaaga aggtcatcct tgacctgccc 1100

 ctggtaattg gcagcagatc aggtctaagc agcagaacat ccagcatggc 1150

 cagccgaacc agctctgaga tgagttgggt agatctgaac atccctgata 1200

 ccccagaagc tcctccctgc tatatggatg tcattcctga agatcaccga 1250

 ttggagagcc caacaactcc tctgctagat gacatggatg gctctcaaga 1300

 cagccctatc tttatgtatg cccctgagtt caagttcatg ccaccaccga 1350

 cttatactga ggtggatccc tgcatcctca acaacaatgt gcagtgagca 1400

 tgtggaagaa aagaagcagc tttacctact tgtttctttt tgtctctctt 1450

 cctggacact cactttttca gagactcaac agtctcgtca atggagtgtg 1500

 ggtccacctt agcctctgac ttcctaatgt aggaggtggt cagcaggcaa 1550

 tctcctgggc cttaaaggat gcggactcat cctcagccag cgcccatgtt 1600

 gtgatacagg ggtgtttgtt ggatgggttt aaaaataact agaaaaactc 1650

 aggcccatcc attttctcag atctccttga aaattgaggc cttttcgata 1700

 gtttcgggtc aggtaaaaat ggcctcctgg cgtaagcttt tcaaggtttt 1750

 ttggaggctt tttgtaaatt gtgataggaa ctttggacct tgaacttacg 1800

 tatcatgtgg agaagagcca atttaacaaa ctaggaagat gaaaagggaa 1850

 attgtggcca aaactttggg aaaaggaggt tcttaaaatc agtgtttccc 1900

 ctttgtgcac ttgtagaaaa aaaagaaaaa ccttctagag ctgatttgat 1950

 ggacaatgga gagagctttc cctgtgatta taaaaaagga agctagctgc 2000

 tctacggtca tctttgctta gagtatactt taacctggct tttaaagcag 2050

 tagtaactgc cccaccaaag gtcttaaaag ccatttttgg agcctattgc 2100

 actgtgttct cctactgcaa atattttcat atgggaggat ggttttctct 2150

 tcatgtaagt ccttggaatt gattctaagg tgatgttctt agcactttaa 2200

 ttcctgtcaa attttttgtt ctccccttct gccatcttaa atgtaagctg 2250

 aaactggtct actgtgtctc tagggttaag ccaaaagaca aaaaaaattt 2300

 tactactttt gagattgccc caatgtacag aattatataa ttctaacgct 2350

 taaatcatgt gaaagggttg ctgctgtcag ccttgcccac tgtgacttca 2400

 aacccaagga ggaactcttg atcaagatgc ccaaccctgt gatcagaacc 2450

 tccaaatact gccatgagaa actagagggc aggtgttcat aaaagccctt 2500

 tgaaccccct tcctgccctg tgttaggaga tagggatatt ggcccctcac 2550

 tgcagctgcc agcacttggt cagtcactct cagccatagc actttgttca 2600

 ctgtcctgtg tcagagcact gagctccacc cttttctgag agttattaca 2650

 gccagaaagt gtgggctgaa gatggttggt ttcatgtggg ggtattatgt 2700

 accc 2704

<210> 170
<211> 391
<212> PRT
<213> Homo sapien

<400> 170
 Met Val Met Phe Lys Lys Ile Lys Ser Phe Glu Val Val Phe Asn
   1               5                  10                  15

 Asp Pro Glu Lys Val Tyr Gly Ser Gly Glu Arg Val Ala Gly Arg
                  20                  25                  30

 Val Ile Val Glu Val Cys Glu Val Thr Arg Val Lys Ala Val Arg
                  35                  40                  45

 Ile Leu Ala Cys Gly Val Ala Lys Val Leu Trp Met Gln Gly Ser
                  50                  55                  60

 Gln Gln Cys Lys Gln Thr Ser Glu Tyr Leu Arg Tyr Glu Asp Thr
                  65                  70                  75

 Leu Leu Leu Glu Asp Gln Pro Thr Gly Glu Asn Glu Met Val Ile
                  80                  85                  90

 Met Arg Pro Gly Asn Lys Tyr Glu Tyr Lys Phe Gly Phe Glu Leu
                  95                 100                 105

 Pro Gln Gly Pro Leu Gly Thr Ser Phe Lys Gly Lys Tyr Gly Cys
                 110                 115                 120

 Val Asp Tyr Trp Val Lys Ala Phe Leu Asp Arg Pro Ser Gln Pro
                 125                 130                 135

 Thr Gln Glu Thr Lys Lys Asn Phe Glu Val Val Asp Leu Val Asp
                 140                 145                 150

 Val Asn Thr Pro Asp Leu Met Ala Pro Val Ser Ala Lys Lys Glu
                 155                 160                 165

 Lys Lys Val Ser Cys Met Phe Ile Pro Asp Gly Arg Val Ser Val
                 170                 175                 180

 Ser Ala Arg Ile Asp Arg Lys Gly Phe Cys Glu Gly Asp Glu Ile
                 185                 190                 195

 Ser Ile His Ala Asp Phe Glu Asn Thr Cys Ser Arg Ile Val Val
                 200                 205                 210

 Pro Lys Ala Ala Ile Val Ala Arg His Thr Tyr Leu Ala Asn Gly
                 215                 220                 225

 Gln Thr Lys Val Leu Thr Gln Lys Leu Ser Ser Val Arg Gly Asn
                 230                 235                 240

 His Ile Ile Ser Gly Thr Cys Ala Ser Trp Arg Gly Lys Ser Leu
                 245                 250                 255

 Arg Val Gln Lys Ile Arg Pro Ser Ile Leu Gly Cys Asn Ile Leu
                 260                 265                 270

 Arg Val Glu Tyr Ser Leu Leu Ile Tyr Val Ser Val Pro Gly Ser
                 275                 280                 285

 Lys Lys Val Ile Leu Asp Leu Pro Leu Val Ile Gly Ser Arg Ser
                 290                 295                 300

 Gly Leu Ser Ser Arg Thr Ser Ser Met Ala Ser Arg Thr Ser Ser
                 305                 310                 315

 Glu Met Ser Trp Val Asp Leu Asn Ile Pro Asp Thr Pro Glu Ala
                 320                 325                 330

 Pro Pro Cys Tyr Met Asp Val Ile Pro Glu Asp His Arg Leu Glu
                 335                 340                 345

 Ser Pro Thr Thr Pro Leu Leu Asp Asp Met Asp Gly Ser Gln Asp
                 350                 355                 360

 Ser Pro Ile Phe Met Tyr Ala Pro Glu Phe Lys Phe Met Pro Pro
                 365                 370                 375

 Pro Thr Tyr Thr Glu Val Asp Pro Cys Ile Leu Asn Asn Asn Val
                 380                 385                 390

 Gln


<210> 171
<211> 2704
<212> DNA
<213> Homo sapien

<400> 171
 gcttagtgta accagcggcg tatatttttt aggcgccttt tcgaaaacct 50

 agtagttaat attcatttgt ttaaatctta ttttattttt aagctcaaac 100

 tgcttaagaa taccttaatt ccttaaagtg aaataatttt ttgcaaaggg 150

 gtttcctcga tttggagctt tttttttctt ccaccgtcat ttctaactct 200

 taaaaccaac tcagttccat catggtgatg ttcaagaaga tcaagtcttt 250

 tgaggtggtc tttaacgacc ctgaaaaggt gtacggcagt ggcgagaggg 300

 tggctggccg ggtgatagtg gaggtgtgtg aagttactcg tgtcaaagcc 350

 gttaggatcc tggcttgcgg agtggctaaa gtgctttgga tgcagggatc 400

 ccagcagtgc aaacagactt cggagtacct gcgctatgaa gacacgcttc 450

 ttctggaaga ccagccaaca ggtgagaatg agatggtgat catgagacct 500

 ggaaacaaat atgagtacaa gttcggcttt gagcttcctc aggggcctct 550

 gggaacatcc ttcaaaggaa aatatgggtg tgtagactac tgggtgaagg 600

 cttttcttga ccgcccgagc cagccaactc aagagacaaa gaaaaacttt 650

 gaagtagtgg atctggtgga tgtcaatacc cctgatttaa tggcacctgt 700

 gtctgctaaa aaagaaaaga aagtttcctg catgttcatt cctgatgggc 750

 gggtgtctgt ctctgctcga attgacagaa aaggattctg tgaaggtgat 800

 gagatttcca tccatgctga ctttgagaat acatgttccc gaattgtggt 850

 ccccaaagct gccattgtgg cccgccacac ttaccttgcc aatggccaga 900

 ccaaggtgct gactcagaag ttgtcatcag tcagaggcaa tcatattatc 950

 tcagggacat gcgcatcatg gcgtggcaag agccttcggg ttcagaagat 1000

 caggccttct atcctgggct gcaacatcct tcgagttgaa tattccttac 1050

 tgatctatgt tagcgttcct ggatccaaga aggtcatcct tgacctgccc 1100

 ctggtaattg gcagcagatc aggtctaagc agcagaacat ccagcatggc 1150

 cagccgaacc agctctgaga tgagttgggt agatctgaac atccctgata 1200

 ccccagaagc tcctccctgc tatatggatg tcattcctga agatcaccga 1250

 ttggagagcc caacaactcc tctgctagat gacatggatg gctctcaaga 1300

 cagccctatc tttatgtatg cccctgagtt caagttcatg ccaccaccga 1350

 cttatactga ggtggatccc tgcatcctca acaacaatgt gcagtgagca 1400

 tgtggaagaa aagaagcagc tttacctact tgtttctttt tgtctctctt 1450

 cctggacact cactttttca gagactcaac agtctcgtca atggagtgtg 1500

 ggtccacctt agcctctgac ttcctaatgt aggaggtggt cagcaggcaa 1550

 tctcctgggc cttaaaggat gcggactcat cctcagccag cgcccatgtt 1600

 gtgatacagg ggtgtttgtt ggatgggttt aaaaataact agaaaaactc 1650

 aggcccatcc attttctcag atctccttga aaattgaggc cttttcgata 1700

 gtttcgggtc aggtaaaaat ggcctcctgg cgtaagcttt tcaaggtttt 1750

 ttggaggctt tttgtaaatt gtgataggaa ctttggacct tgaacttacg 1800

 tatcatgtgg agaagagcca atttaacaaa ctaggaagat gaaaagggaa 1850

 attgtggcca aaactttggg aaaaggaggt tcttaaaatc agtgtttccc 1900

 ctttgtgcac ttgtagaaaa aaaagaaaaa ccttctagag ctgatttgat 1950

 ggacaatgga gagagctttc cctgtgatta taaaaaagga agctagctgc 2000

 tctacggtca tctttgctta gagtatactt taacctggct tttaaagcag 2050

 tagtaactgc cccaccaaag gtcttaaaag ccatttttgg agcctattgc 2100

 actgtgttct cctactgcaa atattttcat atgggaggat ggttttctct 2150

 tcatgtaagt ccttggaatt gattctaagg tgatgttctt agcactttaa 2200

 ttcctgtcaa attttttgtt ctccccttct gccatcttaa atgtaagctg 2250

 aaactggtct actgtgtctc tagggttaag ccaaaagaca aaaaaaattt 2300

 tactactttt gagattgccc caatgtacag aattatataa ttctaacgct 2350

 taaatcatgt gaaagggttg ctgctgtcag ccttgcccac tgtgacttca 2400

 aacccaagga ggaactcttg atcaagatgc ccaaccctgt gatcagaacc 2450

 tccaaatact gccatgagaa actagagggc aggtgttcat aaaagccctt 2500

 tgaaccccct tcctgccctg tgttaggaga tagggatatt ggcccctcac 2550

 tgcagctgcc agcacttggt cagtcactct cagccatagc actttgttca 2600

 ctgtcctgtg tcagagcact gagctccacc cttttctgag agttattaca 2650

 gccagaaagt gtgggctgaa gatggttggt ttcatgtggg ggtattatgt 2700

 accc 2704

<210> 172
<211> 391
<212> PRT
<213> Homo sapien

<400> 172
 Met Val Met Phe Lys Lys Ile Lys Ser Phe Glu Val Val Phe Asn
   1               5                  10                  15

 Asp Pro Glu Lys Val Tyr Gly Ser Gly Glu Arg Val Ala Gly Arg
                  20                  25                  30

 Val Ile Val Glu Val Cys Glu Val Thr Arg Val Lys Ala Val Arg
                  35                  40                  45

 Ile Leu Ala Cys Gly Val Ala Lys Val Leu Trp Met Gln Gly Ser
                  50                  55                  60

 Gln Gln Cys Lys Gln Thr Ser Glu Tyr Leu Arg Tyr Glu Asp Thr
                  65                  70                  75

 Leu Leu Leu Glu Asp Gln Pro Thr Gly Glu Asn Glu Met Val Ile
                  80                  85                  90

 Met Arg Pro Gly Asn Lys Tyr Glu Tyr Lys Phe Gly Phe Glu Leu
                  95                 100                 105

 Pro Gln Gly Pro Leu Gly Thr Ser Phe Lys Gly Lys Tyr Gly Cys
                 110                 115                 120

 Val Asp Tyr Trp Val Lys Ala Phe Leu Asp Arg Pro Ser Gln Pro
                 125                 130                 135

 Thr Gln Glu Thr Lys Lys Asn Phe Glu Val Val Asp Leu Val Asp
                 140                 145                 150

 Val Asn Thr Pro Asp Leu Met Ala Pro Val Ser Ala Lys Lys Glu
                 155                 160                 165

 Lys Lys Val Ser Cys Met Phe Ile Pro Asp Gly Arg Val Ser Val
                 170                 175                 180

 Ser Ala Arg Ile Asp Arg Lys Gly Phe Cys Glu Gly Asp Glu Ile
                 185                 190                 195

 Ser Ile His Ala Asp Phe Glu Asn Thr Cys Ser Arg Ile Val Val
                 200                 205                 210

 Pro Lys Ala Ala Ile Val Ala Arg His Thr Tyr Leu Ala Asn Gly
                 215                 220                 225

 Gln Thr Lys Val Leu Thr Gln Lys Leu Ser Ser Val Arg Gly Asn
                 230                 235                 240

 His Ile Ile Ser Gly Thr Cys Ala Ser Trp Arg Gly Lys Ser Leu
                 245                 250                 255

 Arg Val Gln Lys Ile Arg Pro Ser Ile Leu Gly Cys Asn Ile Leu
                 260                 265                 270

 Arg Val Glu Tyr Ser Leu Leu Ile Tyr Val Ser Val Pro Gly Ser
                 275                 280                 285

 Lys Lys Val Ile Leu Asp Leu Pro Leu Val Ile Gly Ser Arg Ser
                 290                 295                 300

 Gly Leu Ser Ser Arg Thr Ser Ser Met Ala Ser Arg Thr Ser Ser
                 305                 310                 315

 Glu Met Ser Trp Val Asp Leu Asn Ile Pro Asp Thr Pro Glu Ala
                 320                 325                 330

 Pro Pro Cys Tyr Met Asp Val Ile Pro Glu Asp His Arg Leu Glu
                 335                 340                 345

 Ser Pro Thr Thr Pro Leu Leu Asp Asp Met Asp Gly Ser Gln Asp
                 350                 355                 360

 Ser Pro Ile Phe Met Tyr Ala Pro Glu Phe Lys Phe Met Pro Pro
                 365                 370                 375

 Pro Thr Tyr Thr Glu Val Asp Pro Cys Ile Leu Asn Asn Asn Val
                 380                 385                 390

 Gln


<210> 173
<211> 2704
<212> DNA
<213> Homo sapien

<400> 173
 gcttagtgta accagcggcg tatatttttt aggcgccttt tcgaaaacct 50

 agtagttaat attcatttgt ttaaatctta ttttattttt aagctcaaac 100

 tgcttaagaa taccttaatt ccttaaagtg aaataatttt ttgcaaaggg 150

 gtttcctcga tttggagctt tttttttctt ccaccgtcat ttctaactct 200

 taaaaccaac tcagttccat catggtgatg ttcaagaaga tcaagtcttt 250

 tgaggtggtc tttaacgacc ctgaaaaggt gtacggcagt ggcgagaggg 300

 tggctggccg ggtgatagtg gaggtgtgtg aagttactcg tgtcaaagcc 350

 gttaggatcc tggcttgcgg agtggctaaa gtgctttgga tgcagggatc 400

 ccagcagtgc aaacagactt cggagtacct gcgctatgaa gacacgcttc 450

 ttctggaaga ccagccaaca ggtgagaatg agatggtgat catgagacct 500

 ggaaacaaat atgagtacaa gttcggcttt gagcttcctc aggggcctct 550

 gggaacatcc ttcaaaggaa aatatgggtg tgtagactac tgggtgaagg 600

 cttttcttga ccgcccgagc cagccaactc aagagacaaa gaaaaacttt 650

 gaagtagtgg atctggtgga tgtcaatacc cctgatttaa tggcacctgt 700

 gtctgctaaa aaagaaaaga aagtttcctg catgttcatt cctgatgggc 750

 gggtgtctgt ctctgctcga attgacagaa aaggattctg tgaaggtgat 800

 gagatttcca tccatgctga ctttgagaat acatgttccc gaattgtggt 850

 ccccaaagct gccattgtgg cccgccacac ttaccttgcc aatggccaga 900

 ccaaggtgct gactcagaag ttgtcatcag tcagaggcaa tcatattatc 950

 tcagggacat gcgcatcatg gcgtggcaag agccttcggg ttcagaagat 1000

 caggccttct atcctgggct gcaacatcct tcgagttgaa tattccttac 1050

 tgatctatgt tagcgttcct ggatccaaga aggtcatcct tgacctgccc 1100

 ctggtaattg gcagcagatc aggtctaagc agcagaacat ccagcatggc 1150

 cagccgaacc agctctgaga tgagttgggt agatctgaac atccctgata 1200

 ccccagaagc tcctccctgc tatatggatg tcattcctga agatcaccga 1250

 ttggagagcc caacaactcc tctgctagat gacatggatg gctctcaaga 1300

 cagccctatc tttatgtatg cccctgagtt caagttcatg ccaccaccga 1350

 cttatactga ggtggatccc tgcatcctca acaacaatgt gcagtgagca 1400

 tgtggaagaa aagaagcagc tttacctact tgtttctttt tgtctctctt 1450

 cctggacact cactttttca gagactcaac agtctcgtca atggagtgtg 1500

 ggtccacctt agcctctgac ttcctaatgt aggaggtggt cagcaggcaa 1550

 tctcctgggc cttaaaggat gcggactcat cctcagccag cgcccatgtt 1600

 gtgatacagg ggtgtttgtt ggatgggttt aaaaataact agaaaaactc 1650

 aggcccatcc attttctcag atctccttga aaattgaggc cttttcgata 1700

 gtttcgggtc aggtaaaaat ggcctcctgg cgtaagcttt tcaaggtttt 1750

 ttggaggctt tttgtaaatt gtgataggaa ctttggacct tgaacttacg 1800

 tatcatgtgg agaagagcca atttaacaaa ctaggaagat gaaaagggaa 1850

 attgtggcca aaactttggg aaaaggaggt tcttaaaatc agtgtttccc 1900

 ctttgtgcac ttgtagaaaa aaaagaaaaa ccttctagag ctgatttgat 1950

 ggacaatgga gagagctttc cctgtgatta taaaaaagga agctagctgc 2000

 tctacggtca tctttgctta gagtatactt taacctggct tttaaagcag 2050

 tagtaactgc cccaccaaag gtcttaaaag ccatttttgg agcctattgc 2100

 actgtgttct cctactgcaa atattttcat atgggaggat ggttttctct 2150

 tcatgtaagt ccttggaatt gattctaagg tgatgttctt agcactttaa 2200

 ttcctgtcaa attttttgtt ctccccttct gccatcttaa atgtaagctg 2250

 aaactggtct actgtgtctc tagggttaag ccaaaagaca aaaaaaattt 2300

 tactactttt gagattgccc caatgtacag aattatataa ttctaacgct 2350

 taaatcatgt gaaagggttg ctgctgtcag ccttgcccac tgtgacttca 2400

 aacccaagga ggaactcttg atcaagatgc ccaaccctgt gatcagaacc 2450

 tccaaatact gccatgagaa actagagggc aggtgttcat aaaagccctt 2500

 tgaaccccct tcctgccctg tgttaggaga tagggatatt ggcccctcac 2550

 tgcagctgcc agcacttggt cagtcactct cagccatagc actttgttca 2600

 ctgtcctgtg tcagagcact gagctccacc cttttctgag agttattaca 2650

 gccagaaagt gtgggctgaa gatggttggt ttcatgtggg ggtattatgt 2700

 accc 2704

<210> 174
<211> 391
<212> PRT
<213> Homo sapien

<400> 174
 Met Val Met Phe Lys Lys Ile Lys Ser Phe Glu Val Val Phe Asn
   1               5                  10                  15

 Asp Pro Glu Lys Val Tyr Gly Ser Gly Glu Arg Val Ala Gly Arg
                  20                  25                  30

 Val Ile Val Glu Val Cys Glu Val Thr Arg Val Lys Ala Val Arg
                  35                  40                  45

 Ile Leu Ala Cys Gly Val Ala Lys Val Leu Trp Met Gln Gly Ser
                  50                  55                  60

 Gln Gln Cys Lys Gln Thr Ser Glu Tyr Leu Arg Tyr Glu Asp Thr
                  65                  70                  75

 Leu Leu Leu Glu Asp Gln Pro Thr Gly Glu Asn Glu Met Val Ile
                  80                  85                  90

 Met Arg Pro Gly Asn Lys Tyr Glu Tyr Lys Phe Gly Phe Glu Leu
                  95                 100                 105

 Pro Gln Gly Pro Leu Gly Thr Ser Phe Lys Gly Lys Tyr Gly Cys
                 110                 115                 120

 Val Asp Tyr Trp Val Lys Ala Phe Leu Asp Arg Pro Ser Gln Pro
                 125                 130                 135

 Thr Gln Glu Thr Lys Lys Asn Phe Glu Val Val Asp Leu Val Asp
                 140                 145                 150

 Val Asn Thr Pro Asp Leu Met Ala Pro Val Ser Ala Lys Lys Glu
                 155                 160                 165

 Lys Lys Val Ser Cys Met Phe Ile Pro Asp Gly Arg Val Ser Val
                 170                 175                 180

 Ser Ala Arg Ile Asp Arg Lys Gly Phe Cys Glu Gly Asp Glu Ile
                 185                 190                 195

 Ser Ile His Ala Asp Phe Glu Asn Thr Cys Ser Arg Ile Val Val
                 200                 205                 210

 Pro Lys Ala Ala Ile Val Ala Arg His Thr Tyr Leu Ala Asn Gly
                 215                 220                 225

 Gln Thr Lys Val Leu Thr Gln Lys Leu Ser Ser Val Arg Gly Asn
                 230                 235                 240

 His Ile Ile Ser Gly Thr Cys Ala Ser Trp Arg Gly Lys Ser Leu
                 245                 250                 255

 Arg Val Gln Lys Ile Arg Pro Ser Ile Leu Gly Cys Asn Ile Leu
                 260                 265                 270

 Arg Val Glu Tyr Ser Leu Leu Ile Tyr Val Ser Val Pro Gly Ser
                 275                 280                 285

 Lys Lys Val Ile Leu Asp Leu Pro Leu Val Ile Gly Ser Arg Ser
                 290                 295                 300

 Gly Leu Ser Ser Arg Thr Ser Ser Met Ala Ser Arg Thr Ser Ser
                 305                 310                 315

 Glu Met Ser Trp Val Asp Leu Asn Ile Pro Asp Thr Pro Glu Ala
                 320                 325                 330

 Pro Pro Cys Tyr Met Asp Val Ile Pro Glu Asp His Arg Leu Glu
                 335                 340                 345

 Ser Pro Thr Thr Pro Leu Leu Asp Asp Met Asp Gly Ser Gln Asp
                 350                 355                 360

 Ser Pro Ile Phe Met Tyr Ala Pro Glu Phe Lys Phe Met Pro Pro
                 365                 370                 375

 Pro Thr Tyr Thr Glu Val Asp Pro Cys Ile Leu Asn Asn Asn Val
                 380                 385                 390

 Gln


<210> 175
<211> 1399
<212> DNA
<213> Homo sapien

<400> 175
 agtgtgaaat cttcagagaa gaatttctct ttagttcttt gcaagaaggt 50

 agagataaag acactttttc aaaaatggca atggtatcag aattcctcaa 100

 gcaggcctgg tttattgaaa atgaagagca ggaatatgtt caaactgtga 150

 agtcatccaa aggtggtccc ggatcagcgg tgagccccta tcctaccttc 200

 aatccatcct cggatgtcgc tgccttgcat aaggccataa tggttaaagg 250

 tgtggatgaa gcaaccatca ttgacattct aactaagcga aacaatgcac 300

 agcgtcaaca gatcaaagca gcatatctcc aggaaacagg aaagcccctg 350

 gatgaaacac ttaagaaagc ccttacaggt caccttgagg aggttgtttt 400

 agctctgcta aaaactccag cgcaatttga tgctgatgaa cttcgtgctg 450

 ccatgaaggg ccttggaact gatgaagata ctctaattga gattttggca 500

 tcaagaacta acaaagaaat cagagacatt aacagggtct acagagagga 550

 actgaagaga gatctggcca aagacataac ctcagacaca tctggagatt 600

 ttcggaacgc tttgctttct cttgctaagg gtgaccgatc tgaggacttt 650

 ggtgtgaatg aagacttggc tgattcagat gccagggcct tgtatgaagc 700

 aggagaaagg agaaagggga cagacgtaaa cgtgttcaat accatcctta 750

 ccaccagaag ctatccacaa cttcgcagag tgtttcagaa atacaccaag 800

 tacagtaagc atgacatgaa caaagttctg gacctggagt tgaaaggtga 850

 cattgagaaa tgcctcacag ctatcgtgaa gtgcgccaca agcaaaccag 900

 ctttctttgc agagaagctt catcaagcca tgaaaggtgt tggaactcgc 950

 cataaggcat tgatcaggat tatggtttcc cgttctgaaa ttgacatgaa 1000

 tgatatcaaa gcattctatc agaagatgta tggtatctcc ctttgccaag 1050

 ccatcctgga tgaaaccaaa ggagattatg agaaaatcct ggtggctctt 1100

 tgtggaggaa actaaacatt cccttgatgg tctcaagcta tgatcagaag 1150

 actttaatta tatattttca tcctataagc ttaaatagga aagtttcttc 1200

 aacaggatta cagtgtagct acctacatgc tgaaaaatat agcctttaaa 1250

 tcatttttat attataactc tgtataatag agataagtcc attttttaaa 1300

 aatgttttcc ccaaaccata aaaccctata caagttgttc tagtaacaat 1350

 acatgagaaa gatgtctatg tagctgaaaa taaaatgacg tcacaagac 1399

<210> 176
<211> 346
<212> PRT
<213> Homo sapien

<400> 176
 Met Ala Met Val Ser Glu Phe Leu Lys Gln Ala Trp Phe Ile Glu
   1               5                  10                  15

 Asn Glu Glu Gln Glu Tyr Val Gln Thr Val Lys Ser Ser Lys Gly
                  20                  25                  30

 Gly Pro Gly Ser Ala Val Ser Pro Tyr Pro Thr Phe Asn Pro Ser
                  35                  40                  45

 Ser Asp Val Ala Ala Leu His Lys Ala Ile Met Val Lys Gly Val
                  50                  55                  60

 Asp Glu Ala Thr Ile Ile Asp Ile Leu Thr Lys Arg Asn Asn Ala
                  65                  70                  75

 Gln Arg Gln Gln Ile Lys Ala Ala Tyr Leu Gln Glu Thr Gly Lys
                  80                  85                  90

 Pro Leu Asp Glu Thr Leu Lys Lys Ala Leu Thr Gly His Leu Glu
                  95                 100                 105

 Glu Val Val Leu Ala Leu Leu Lys Thr Pro Ala Gln Phe Asp Ala
                 110                 115                 120

 Asp Glu Leu Arg Ala Ala Met Lys Gly Leu Gly Thr Asp Glu Asp
                 125                 130                 135

 Thr Leu Ile Glu Ile Leu Ala Ser Arg Thr Asn Lys Glu Ile Arg
                 140                 145                 150

 Asp Ile Asn Arg Val Tyr Arg Glu Glu Leu Lys Arg Asp Leu Ala
                 155                 160                 165

 Lys Asp Ile Thr Ser Asp Thr Ser Gly Asp Phe Arg Asn Ala Leu
                 170                 175                 180

 Leu Ser Leu Ala Lys Gly Asp Arg Ser Glu Asp Phe Gly Val Asn
                 185                 190                 195

 Glu Asp Leu Ala Asp Ser Asp Ala Arg Ala Leu Tyr Glu Ala Gly
                 200                 205                 210

 Glu Arg Arg Lys Gly Thr Asp Val Asn Val Phe Asn Thr Ile Leu
                 215                 220                 225

 Thr Thr Arg Ser Tyr Pro Gln Leu Arg Arg Val Phe Gln Lys Tyr
                 230                 235                 240

 Thr Lys Tyr Ser Lys His Asp Met Asn Lys Val Leu Asp Leu Glu
                 245                 250                 255

 Leu Lys Gly Asp Ile Glu Lys Cys Leu Thr Ala Ile Val Lys Cys
                 260                 265                 270

 Ala Thr Ser Lys Pro Ala Phe Phe Ala Glu Lys Leu His Gln Ala
                 275                 280                 285

 Met Lys Gly Val Gly Thr Arg His Lys Ala Leu Ile Arg Ile Met
                 290                 295                 300

 Val Ser Arg Ser Glu Ile Asp Met Asn Asp Ile Lys Ala Phe Tyr
                 305                 310                 315

 Gln Lys Met Tyr Gly Ile Ser Leu Cys Gln Ala Ile Leu Asp Glu
                 320                 325                 330

 Thr Lys Gly Asp Tyr Glu Lys Ile Leu Val Ala Leu Cys Gly Gly
                 335                 340                 345

 Asn


<210> 177
<211> 3322
<212> DNA
<213> Homo sapien

<400> 177
 gaaagctgta tttgctgcac gtggaaatct ccgttatttt ccagcaccca 50

 acagtagcgt aatgggagta acggacttaa cctcatttct ctttcagagc 100

 atttagcctt catatgccct tccctgcatg cttcccccag gccgtcaaga 150

 cttgagttct gcctcgcttc ccggcgcggt cgcagccctc agcccactta 200

 ggataatggc gacagctgag gtactgaaca ttggtaaaaa attatatgag 250

 ggtaaaacaa aagaagtcta cgaattgtta gacagtccag gaaaagtcct 300

 cctgcagtcc aaggaccaga ttacagcagg aaatgcagct agaaaaaacc 350

 acctggaagg aaaagctgca atctcaaata aaatcaccag ttgtattttt 400

 cagttattac aggaagcagg tattaaaact gccttcacca gaaaatgtgg 450

 ggagacagct ttcattgcac cgcagtgtga aatgattcca attgaatggg 500

 tttgcagaag aatagcaact ggttcttttc tcaaaagaaa tcctggtgtc 550

 aaggaaggat ataagtttta cccacctaaa gtggagttgt ttttcaagga 600

 tgatgccaat aatgacccac agtggtctga ggaacagctg attgctgcaa 650

 aattttgctt tgctggactt cttataggcc agactgaagt ggatatcatg 700

 agtcatgcta cacaggctat atttgaaata ctggagaaat cctggttgcc 750

 ccagaattgt acactggttg atatgaagat tgaatttggt gttgatgtaa 800

 ccaccaaaga aattgttctt gctgatgtta ttgacaatga ttcctggaga 850

 ctctggccat caggagatcg aagccaacag aaagacaaac agtcttatcg 900

 ggacctcaaa gaagtaactc ctgaagggct ccaaatggta aagaaaaact 950

 ttgagtgggt tgcagagaga gtagagttgc ttttgaaatc agaaagtcag 1000

 tgcagggttg tagtgttgat gggctctact tctgatcttg gtcactgtga 1050

 aaaaatcaag aaggcctgtg gaaattttgg cattccatgt gaacttcgag 1100

 taacatctgc gcataaagga ccagatgaaa ctctgaggat taaagctgag 1150

 tatgaagggg atggcattcc tactgtattt gtggcagtgg caggcagaag 1200

 taatggtttg ggaccagtga tgtctgggaa cactgcatat ccagttatca 1250

 gctgtcctcc cctcacacca gactggggag ttcaggatgt gtggtcttct 1300

 cttcgactac ccagtggtct tggctgttca accgtacttt ctccagaagg 1350

 atcagctcaa tttgctgctc agatatttgg gttaagcaac catttggtat 1400

 ggagcaaact gcgagcaagc attttgaaca catggatttc cttgaagcag 1450

 gctgacaaga aaatcagaga atgtaattta taagaaagaa tgccattgaa 1500

 ttttttaggg gaaaaactac aaatttctaa tttagctgaa ggaaaatcaa 1550

 gcaagatgaa aaggtaattt taaattagag aacacaaata aaatgtatta 1600

 gtgaataaat gcttctctag atccatatta ataaacatga gcatctaacc 1650

 cctcctttct taggctagac accaagatat ttcagccagc ctttatcatt 1700

 cctcttactt tatccttttt ccttaagtat tggtggtcac tactattgag 1750

 tttcttcctt aacactgatt aaatgatctt aactccctca gctaaaactg 1800

 gcattactga ctcccagcta tatttctcca gacttgcatt tttttttttt 1850

 tttttgagac agggtctcac tgtcgcccag gctggagtgc agtggcgtga 1900

 tctcagttca ctgctgcttt ccctcctggg ctcaagcagt tctcccacct 1950

 cagcctctcg actaacaggg actataatct tgcagcacca tgccgagcta 2000

 attttatttt ttgtagagat gagctctcac tatgtcaccc aggttcgtct 2050

 caaactcctg aaccctagta attctcctat ctcagcctcc caaagtgcta 2100

 gggttacaga catgagccac tgtgcctgtc tagacttgta ctttcaactg 2150

 tccatttctc cctgtctgtc ccatgggcac tcatgaaaaa acagaatgct 2200

 cccaacttta ttcatcttcc aagcctgtag ctcttggtat actcactgtt 2250

 gcaagtcaga agcttgattt catcattgat gtttttctca cgtttcacat 2300

 ctcactcatc accaagtcat gttggtgtta atttctgatt aacccttgaa 2350

 tttaccgtct tctcatcctc tgtacaaaag cctcaagtga gggtcaaatt 2400

 caacattatc ctgatctaga cagcccccat tctcaatcca cccttttcca 2450

 agttgattgc ccaaggactt ctaacaataa actctctttt gcaccacaga 2500

 cttctttgaa aatatacatg ctgttgaccc tctctgtaga aaaccgcaca 2550

 cataaaactt accaacagat ttcattggtt cttgggttct cccgaagcct 2600

 atccatggtt tatagattaa gaattgatga ggtagctggg cacagtggct 2650

 cacacctacg atcacagcac ttcgggaggc tgaagcaagc agatcacttg 2700

 aggtcaggag tttgagacca gcctggccaa catggtgaaa ccctgtctct 2750

 actaaaaata caaaaagtag ccagccgtga tgacaggcac ctgtaatccc 2800

 agctactcgg gaggctgagg catgagaatt gcttgaaccc gggaggcgga 2850

 ggttgcagtg agcctggatc atgccactgc actccaacct gggcagcaga 2900

 gcaagactct gtctcaaaag gggaaaaaaa aaattgctga tgtgacccat 2950

 gaagggaact cattttcctc gtaattttgg actgccacac attggtacct 3000

 ttagttctct gaaggcccac gtttttatca ttaagaccta tttgttagct 3050

 agtagagctt tatgttcgct gtccatgaaa ccttctgtaa ccacagtgac 3100

 tacaagtagt tctttctcta ttgaattatt aggtccagaa tagaagatgt 3150

 cattgtacac tttatttccc tcacactgtg ttatgctctg atgtgctatg 3200

 cttagctatc tgtcagagat tagtaaatta taaaactcat gtgtactact 3250

 taagtttata tcttatgcta gtttataaga acaattaaaa ggacttagaa 3300

 gattaaaaaa aaaaaaaaaa aa 3322

<210> 178
<211> 425
<212> PRT
<213> Homo sapien

<400> 178
 Met Ala Thr Ala Glu Val Leu Asn Ile Gly Lys Lys Leu Tyr Glu
   1               5                  10                  15

 Gly Lys Thr Lys Glu Val Tyr Glu Leu Leu Asp Ser Pro Gly Lys
                  20                  25                  30

 Val Leu Leu Gln Ser Lys Asp Gln Ile Thr Ala Gly Asn Ala Ala
                  35                  40                  45

 Arg Lys Asn His Leu Glu Gly Lys Ala Ala Ile Ser Asn Lys Ile
                  50                  55                  60

 Thr Ser Cys Ile Phe Gln Leu Leu Gln Glu Ala Gly Ile Lys Thr
                  65                  70                  75

 Ala Phe Thr Arg Lys Cys Gly Glu Thr Ala Phe Ile Ala Pro Gln
                  80                  85                  90

 Cys Glu Met Ile Pro Ile Glu Trp Val Cys Arg Arg Ile Ala Thr
                  95                 100                 105

 Gly Ser Phe Leu Lys Arg Asn Pro Gly Val Lys Glu Gly Tyr Lys
                 110                 115                 120

 Phe Tyr Pro Pro Lys Val Glu Leu Phe Phe Lys Asp Asp Ala Asn
                 125                 130                 135

 Asn Asp Pro Gln Trp Ser Glu Glu Gln Leu Ile Ala Ala Lys Phe
                 140                 145                 150

 Cys Phe Ala Gly Leu Leu Ile Gly Gln Thr Glu Val Asp Ile Met
                 155                 160                 165

 Ser His Ala Thr Gln Ala Ile Phe Glu Ile Leu Glu Lys Ser Trp
                 170                 175                 180

 Leu Pro Gln Asn Cys Thr Leu Val Asp Met Lys Ile Glu Phe Gly
                 185                 190                 195

 Val Asp Val Thr Thr Lys Glu Ile Val Leu Ala Asp Val Ile Asp
                 200                 205                 210

 Asn Asp Ser Trp Arg Leu Trp Pro Ser Gly Asp Arg Ser Gln Gln
                 215                 220                 225

 Lys Asp Lys Gln Ser Tyr Arg Asp Leu Lys Glu Val Thr Pro Glu
                 230                 235                 240

 Gly Leu Gln Met Val Lys Lys Asn Phe Glu Trp Val Ala Glu Arg
                 245                 250                 255

 Val Glu Leu Leu Leu Lys Ser Glu Ser Gln Cys Arg Val Val Val
                 260                 265                 270

 Leu Met Gly Ser Thr Ser Asp Leu Gly His Cys Glu Lys Ile Lys
                 275                 280                 285

 Lys Ala Cys Gly Asn Phe Gly Ile Pro Cys Glu Leu Arg Val Thr
                 290                 295                 300

 Ser Ala His Lys Gly Pro Asp Glu Thr Leu Arg Ile Lys Ala Glu
                 305                 310                 315

 Tyr Glu Gly Asp Gly Ile Pro Thr Val Phe Val Ala Val Ala Gly
                 320                 325                 330

 Arg Ser Asn Gly Leu Gly Pro Val Met Ser Gly Asn Thr Ala Tyr
                 335                 340                 345

 Pro Val Ile Ser Cys Pro Pro Leu Thr Pro Asp Trp Gly Val Gln
                 350                 355                 360

 Asp Val Trp Ser Ser Leu Arg Leu Pro Ser Gly Leu Gly Cys Ser
                 365                 370                 375

 Thr Val Leu Ser Pro Glu Gly Ser Ala Gln Phe Ala Ala Gln Ile
                 380                 385                 390

 Phe Gly Leu Ser Asn His Leu Val Trp Ser Lys Leu Arg Ala Ser
                 395                 400                 405

 Ile Leu Asn Thr Trp Ile Ser Leu Lys Gln Ala Asp Lys Lys Ile
                 410                 415                 420

 Arg Glu Cys Asn Leu
                 425

<210> 179
<211> 4878
<212> DNA
<213> Homo sapien

<400> 179
 tccgcgtcag caagctgcct gcagctgtcc tgactgcgcc ctgagtggag 50

 gtaccaagtg acactgtttc tccttctagg aacagaagcg tttggagaac 100

 agtcccagcc ttgtgacact gggcccatat cagcgtttag cccaccaggg 150

 tccacccagc acctgcgctc ccaagctgtc acaatgcaaa caacgctatc 200

 aagatctcac aggagaagct gctgctatca tgaagccaac tgtctttgct 250

 catggcgata cgagctggag aaatacagag ttatacttag taggtgaacc 300

 cttgctgata gcaggacatg tatacaggtc cgggtggacc tccaggacct 350

 gggctacgag acttgtggcc aaagcaagaa tgaggctgaa caggaggaaa 400

 ccaccagtcc cggactacaa ccatagggcc acccaccaca ttgaaaacca 450

 gaagagcatt ttgctgccgc cgagcgtgga cgcaggcgga tctctgaaga 500

 gctgggtcgc cagcctctcc cgcgcacgtt gcctggcctc cagcacctac 550

 ttggtcccgc gcgctccctc gtgtcgcccc tcggagcagc agccgccgcg 600

 gtcgccgcta cccggaaaga agtcagagac gccgcgaggt cgccgccacc 650

 gccatgccca agaataaagg taaaggaggt aaaaacagac gcaggggtaa 700

 gaatgagaat gaatctgaaa aaagagaact ggtattcaaa gaggatggtc 750

 aggagtatgc tcaggtaatc aaaatgttgg gaaatggacg gctagaagca 800

 atgtgtttcg atggtgtaaa gaggttatgt cacatcagag gaaaattgag 850

 aaaaaaggtt tggataaata cctcggacat tattttggtt ggtctccgag 900

 actaccagga taacaaagct gatgtaattt taaaatacaa tgcagacgaa 950

 gctagaagtc tgaaggcata cggcgagctt ccagagcatg ctaaaatcaa 1000

 tgaaactgat acatttggtc ctggagatga tgatgaaatt cagtttgatg 1050

 acattggaga tgatgatgaa gatattgatg acatctaaat tgaactcaac 1100

 attttacatt ccatcttttc tgaagattgt cctacaattt ggattttgat 1150

 catgacaaag aagattaaaa tttcattagc atgaatgcaa tttgttaaag 1200

 cagactgatt tgtttctaag atatttttgg tttttttaaa actgataata 1250

 atgctgaatt atcttaagtg agatgttaag cccactttgt tcttttaatg 1300

 taatggagct tatgggtaga agaccatgtc tactaattac aaaaaaaaaa 1350

 aaaaaccatg cattgctgct tttcctacca cttccagtaa gaaaatgggt 1400

 gttttgaaga aatcatttgc cttgtcctca cggaatctga ttaagccctg 1450

 gcctcttgat tgtatagagt cattgtgtat attccagtta cctagatatt 1500

 cccttgagat tttgatacaa tttgagggag gcagaagtct gcagttgaag 1550

 aaaaaaaata agtctgtttg tcatatttaa gtagcctgtg gctattttta 1600

 tactgatttt gatatcatgt tcttttcata gtcgtatttt gccaccgtaa 1650

 acataaaaaa aaaaaaagat ttccaaaatg ccgttttcag aacctgggtt 1700

 ttaatagcag tattgaattt gtaagcttag tagttgcaga aattgaacac 1750

 taggtggcac tcagttatct taacagggga agtactgata caattgttga 1800

 cttttctttt actatgtgta agaaataccc caaacatgaa aagattgttt 1850

 tgatcatatg catgtatgta gaatattttt gcagagcaga aagattatgt 1900

 tagaagtgtg atttttattt tcagaagtca tatacatgta agctacaatt 1950

 ttgagtgctt tataaacact taagatatat atataaattt taatttcata 2000

 gcaacttgta aaaaataaaa tacttgttga aaagcctttt tcaacatatc 2050

 cctaagctaa gggaagagga aggaataaca actcagtgaa aagatggtct 2100

 ccagtttctg aatgaaaaag ctacagctga gaaataaaat aaaatgtcat 2150

 gctgcagaat atgttatacc cttattttgt gttaaggata tattttatta 2200

 tgtgaatggt tttgtttttg ttttttgttt ttgttttttg cttgtattgg 2250

 gaattagctt tactggtaac ttccttattt agtttttagt ggtcaactct 2300

 aataaaatga aactagggct gagctagtta gccctcacta gccaaactga 2350

 aactctatgc aacattaaaa gaagagatcc atcatgtagc ttgtgacact 2400

 tttattttat tagtcaccgg ggaacttttc agtgatgaaa atacacaggg 2450

 taataaacct tcacatggct tcaaaaggaa aacaagcaaa tcttctctaa 2500

 tctactctta ctataatttc ctaagtgtac accaaactct ggatttaaaa 2550

 atctgaagta ctatagaaca ttaagttgaa gaatggaaat taagagtacg 2600

 tattcatggt ttatatttct tattctatgg agttcgtgaa cacatctagg 2650

 tggaatgcat ctgagactaa gggctggttt ttaatcctca taagaaacca 2700

 gccttgaaga attaacaatt ctcttcattg gtattctaaa cctcctaaga 2750

 tatttaggct tctgtacata aaagtgtttt tgctaaattt acagtatata 2800

 tagatccttt catattattt tactaagaat gtttgaactt tgcatatttg 2850

 atatagttcc tggtaggaat agcacagctc aaacattagt ttttctactt 2900

 acctcctcta acacgtggtt tgtctggaga gtttctaaaa attcagctat 2950

 aaccccagtt catgtattta ctggtgattg ttcttgctga ggtagtaaca 3000

 gcccaatctt gggctgttaa atcctaggaa atctcgaatc atagtgatta 3050

 aaatagttgg ggtaaagttg tagcttatat gcaatactac ttggaggaat 3100

 tcttctacta atttgtattt aatgtggaaa ttgtatagtt tcattgattt 3150

 aatcataaat aatggaaatg gtctccaaga agttttattt ttcatttttt 3200

 tgcttataca ctctgattcc tataatacag tgctataagc tatgcacaga 3250

 aaataaaatg tttgaaatcc aagaataatg gttcttactg ctaagaggga 3300

 gtaatagtta ttactaatga ttttgattgg gttgcatttt tgttgcaatg 3350

 tttattccac ttgcagttag aatatgaata tgttttatca ctagtgtggc 3400

 taaataacca aacatttgtg taaaaaaaaa aaaaagccaa gatttcattg 3450

 tttgttgaat atttcttaag catctggccc ctaaagagac cgcttcttac 3500

 caagcctgta aactatgcat gatggaaatt cttgtatttt atttaggaat 3550

 ggctgttggt ttactcacca catctgtgga atcatggcta taaatgtttg 3600

 cttacaaact ctttgtgact tgtaatttaa cttaatctca tctaatgtaa 3650

 atattagatt atgatgttca gtaacatctt ccataggtat aaactgctgt 3700

 cattattgat ttcagagtaa ctctgagtaa tcaaataggt aaaagcatgt 3750

 tttgagtaaa atagctagat ttatacttta cttgtataca gacttaacaa 3800

 caaccggtat tgactggatt gacagctaaa gtatcagaat gaaagcaagg 3850

 tttttttgat gttacctgac tgtcataaag atgaaaatga tttgtattgg 3900

 tatgaaatgc ttatctttat tctacttcgt aagggtaagt tttatttata 3950

 ctctttggac tcccatgaac ttttgcacac tgctttgtgt ttttggttta 4000

 ccctaaacta ccatcctttt tatctttgct ttttttcttc ctattcagaa 4050

 aagagcaaaa tgtgaaaaga cacaagactc tcaggtatag aatgaactga 4100

 gcaatttgga gaatgtattg gactttgtcc tctcttattc ccccctccta 4150

 gccctgcaag ttgctaggta cttgtgaggc agtgtactgg agaggggaga 4200

 gcatggatcc tggggtcaaa gggcctttgc ccccaccctt acttggccct 4250

 ctacctgcag gtgaccactg gcacattctc ctgcttgtct cagcttcagg 4300

 ttcttcacct ctaagatggg gatgatgaaa acagtacctg tcatgcagaa 4350

 ttgttgggag gattgataat ttagatgttt atacatgtaa tgtacttaga 4400

 tcagtgtctg ctcttttcac ttgatatcca gtactatgta agatagaagg 4450

 tgcatgtctt ctgtattctg tatttcccat ttcttttgcg tgcagtcttt 4500

 gattcgtaca atagaaggaa cacgtagaat gtatatttgt acattcatgt 4550

 caacatagta tttgaaattg ctaccaaact catttaattt ggcataagac 4600

 taacagatga agtctctcat ttgcttgaag atattttaca aaataccaac 4650

 tgttctatat ttctttagaa aaagattata gttattaata ttgatacctc 4700

 tgataatatt ttattcttaa atcttcagtg attcctttta ctatagattc 4750

 atgacagcta attagtacta actgatttag aggtttcctt tcccatcata 4800

 tggaatgatg taaagaaatc agatacaaac tactgcaatt agaaaataaa 4850

 atatgaacaa ctttcaacaa tgtaaaaa 4878

<210> 180
<211> 145
<212> PRT
<213> Homo sapien

<400> 180
 Met Lys Pro Thr Val Phe Ala His Gly Asp Thr Ser Trp Arg Asn
   1               5                  10                  15

 Thr Glu Leu Tyr Leu Val Gly Glu Pro Leu Leu Ile Ala Gly His
                  20                  25                  30

 Val Tyr Arg Ser Gly Trp Thr Ser Arg Thr Trp Ala Thr Arg Leu
                  35                  40                  45

 Val Ala Lys Ala Arg Met Arg Leu Asn Arg Arg Lys Pro Pro Val
                  50                  55                  60

 Pro Asp Tyr Asn His Arg Ala Thr His His Ile Glu Asn Gln Lys
                  65                  70                  75

 Ser Ile Leu Leu Pro Pro Ser Val Asp Ala Gly Gly Ser Leu Lys
                  80                  85                  90

 Ser Trp Val Ala Ser Leu Ser Arg Ala Arg Cys Leu Ala Ser Ser
                  95                 100                 105

 Thr Tyr Leu Val Pro Arg Ala Pro Ser Cys Arg Pro Ser Glu Gln
                 110                 115                 120

 Gln Pro Pro Arg Ser Pro Leu Pro Gly Lys Lys Ser Glu Thr Pro
                 125                 130                 135

 Arg Gly Arg Arg His Arg His Ala Gln Glu
                 140                 145

<210> 181
<211> 1439
<212> DNA
<213> Homo sapien

<400> 181
 cggggaggac ggtctgcata ctcgctgccc gccggctccc tcccccgcgt 50

 ccctgcgacc gccgcggcga agatggcctc aggagtgcaa gtagctgatg 100

 aagtatgtcg cattttttat gacatgaaag ttcgtaaatg ctccacacca 150

 gaagaaatca agaaaagaaa gaaggctgtc attttttgtc tcagtgcaga 200

 caaaaagtgc atcattgtag aagaaggcaa agagatcttg gttggagatg 250

 ttggtgtaac cataactgat cctttcaagc attttgtggg aatgcttcct 300

 gaaaaagatt gtcgctatgc tttgtatgat gcaagctttg aaacaaaaga 350

 atccagaaaa gaagagttga tgtttttttt gtgggcacca gaactagcac 400

 ctctgaaaag taaaatgatc tatgcaagct ccaaggatgc aattaaaaag 450

 aaatttcaag gcataaaaca tgaatgtcaa gcaaatggac cagaagatct 500

 caatcgggct tgtattgctg aaaagttagg tggatcctta attgtagcct 550

 ttgaaggatg ccctgtgtag attattcagt gccacaaatt gaaagcttcc 600

 atgtttaatg ttatcctctt gctatataaa taaagcaaat atatttaggc 650

 cagggtctca ctgaggggga gctgtcttgt catcttttag agtaaactat 700

 tctataaaca tatgcaaaca gccctaaata aatctaaagt ctaaagtttt 750

 attgatgtga aattaaattc ttattggcca aatgcctgtt ttgatgagtt 800

 gatttataaa gatttttgtt aagctcagga ttttaaatta cacagttcac 850

 aaacagtaaa ggccatgtga agagaattat tacatcttta ttaacctcag 900

 catttacttt gtttcttttg cttaggaaat tgctcataat ctggttataa 950

 ttttggtcca aattctttat tcttccttga gctaagcaga ataatggaat 1000

 ataatatgtc ttcataatat aacaacacta atacactaat agtaagatta 1050

 agttaggcag tcttctacca aatgtgtaat ggagattgcc tcaaaattgt 1100

 gtccacataa tccacgctca tcttgcaaag cgctatttca ggcacatcat 1150

 tggaatacag gaagtagccc tgcacctgcc agtgagctcg ccattcactg 1200

 attggaagag tgacctggca tcttggaaat cattgtgtgt cttcaggaga 1250

 atgtgcagtg tcttgtaaca actaattaat aatgcaaatt agggctacat 1300

 tgtaatctgc tttgttaatg aaaatgataa aacagaatat tgacaagcta 1350

 ggacacctgt ggtatcttta attgtatctc cttcagaagt ttgcttctta 1400

 tggtataata aagtatggaa gaataaaaaa aaaaaaaaa 1439

<210> 182
<211> 165
<212> PRT
<213> Homo sapien

<400> 182
 Met Ala Ser Gly Val Gln Val Ala Asp Glu Val Cys Arg Ile Phe
   1               5                  10                  15

 Tyr Asp Met Lys Val Arg Lys Cys Ser Thr Pro Glu Glu Ile Lys
                  20                  25                  30

 Lys Arg Lys Lys Ala Val Ile Phe Cys Leu Ser Ala Asp Lys Lys
                  35                  40                  45

 Cys Ile Ile Val Glu Glu Gly Lys Glu Ile Leu Val Gly Asp Val
                  50                  55                  60

 Gly Val Thr Ile Thr Asp Pro Phe Lys His Phe Val Gly Met Leu
                  65                  70                  75

 Pro Glu Lys Asp Cys Arg Tyr Ala Leu Tyr Asp Ala Ser Phe Glu
                  80                  85                  90

 Thr Lys Glu Ser Arg Lys Glu Glu Leu Met Phe Phe Leu Trp Ala
                  95                 100                 105

 Pro Glu Leu Ala Pro Leu Lys Ser Lys Met Ile Tyr Ala Ser Ser
                 110                 115                 120

 Lys Asp Ala Ile Lys Lys Lys Phe Gln Gly Ile Lys His Glu Cys
                 125                 130                 135

 Gln Ala Asn Gly Pro Glu Asp Leu Asn Arg Ala Cys Ile Ala Glu
                 140                 145                 150

 Lys Leu Gly Gly Ser Leu Ile Val Ala Phe Glu Gly Cys Pro Val
                 155                 160                 165

<210> 183
<211> 2310
<212> DNA
<213> Homo sapien

<400> 183
 acttccgttt ttgctgggta ggcgacccgg acggagggcc ggcgaggtgc 50

 ggggtctggt gatgcgagct gcgcctctcg gcaagatttc gcgctgccca 100

 tcccgggccc tttcatcagt aatcggtagt ggatcactct gccaagcggc 150

 aggaagaatt aaggaaacga caaggagacg ctcggctctc tcccgcttgg 200

 ctccttgcgg cctcctcttc ccttcgctcc ggcccggtga aactgaactt 250

 ataatcgtca ctggattgta agtacccgag gcgaagagag ctcgctgagc 300

 cctgattttt tgagtgtctt tgttccggga gagtttgtga gttgaaagta 350

 tctctgctgg gctttctggg ccgaaaaccg ttccggggga gccgccattt 400

 gctttcctgt tccctagcta gctagctagc tctctccgcg ttgtccggca 450

 gcggcaccta gaggttggga cttggcattg catctgattt aatgaactta 500

 agtctgtgaa taagcctttg tgttaacgac tggtattcgg tcacagcata 550

 tttagagaaa agacttggag cttaaataaa aactaaggca aaatagacgc 600

 ttagctgctg atctacagag aacttcttgt aattaaaaga tttcaattca 650

 tagcaaactg gtgttttaaa ctattgcagt agctggaact ttttagtgta 700

 accagcattt attggagaag tgaatcacaa ggaaataaag atgagtaaaa 750

 gcaaagatga tgctcctcac gaactggaga gccagtttat cttacgtctg 800

 cctccagaat atgcctctac tgtgagaagg gcagtacagt ctggtcatgt 850

 caacctcaag gacagactga caattgagtt acatcctgat gggcgtcatg 900

 gaatcgtcag agtggaccgt gttccattgg cctcaaaatt agtagacctg 950

 ccctgtgtta tggaaagctt gaaaaccatt gataaaaaaa ctttttacaa 1000

 gacagctgat atctgtcaga tgcttgtatc cacagttgat ggtgatctct 1050

 atcctcctgt ggaggagcca gttgctagca ctgatcctaa agcaagcaag 1100

 aaaaaggata aggacaaaga gaaaaagttt atctggaacc acggaattac 1150

 tctgcctcta aagaatgtca ggaagagaag gttccggaag acagcaaaga 1200

 agaaatatat tgaatctcca gatgttgaaa aagaagtgaa acgattgctg 1250

 agtacagatg ctgaagctgt tagtactcgg tgggaaataa ttgccgaaga 1300

 tgaaacaaag gaggcagaaa atcaaggcct ggatatctct tctccaggaa 1350

 tgtctggtca caggcagggc catgactcat tagaacatga tgagcttcgg 1400

 gagatattca atgacctcag cagcagcagt gaggatgaag atgagaccca 1450

 gcatcaagat gaagaagata taaacatcat tgacacggag gaagatctgg 1500

 agagacagct acaggacaag ctaaatgaat cagatgaaca gcaccaggaa 1550

 aatgaaggaa ccaatcagct ggttatggga attcagaagc agattgacaa 1600

 catgaaaggc aagctccaag agacccagga cagggcaaaa cgacaagagg 1650

 atctcatcat gaaagtggaa aatctggctc tcaagaacag atttcaggct 1700

 gtactggatg agctcaaaca aaaggaagac cgagaaaagg agcaactcag 1750

 ctctttgcaa gaggagctag aatcactcct agagaagtaa aaagaactga 1800

 tatttaattt cagtcttcag actggtcagc attagaaaat tcttggcttt 1850

 attgtactgg gtattaagac cttgctcttc ctagtccttt taatgctgtg 1900

 tgttctgtta agttctttca tttgtttgta attttgtttt tcagcaaatt 1950

 tatattgttt tgctaggtgt tcatcctata agaagcagga ttgtataggc 2000

 agaaaaatga ttgtaggaaa gttgcaggat tagcggaatg tatggttcaa 2050

 ccttaattat agcttcattg caggacttta ctgtttctcc attttctaga 2100

 agctgctgtt gctgctttgt gatgacgtga gatcaataag aagaacctag 2150

 tctagagaca atgatgctag tttgcatatg ttttcctatg caataattgt 2200

 tttcccagtt attcaaagca gctttctata tgtagagatg caaattatta 2250

 agttgtttcc aatacaataa ataaaagcat ctgtttttca ctttaaaaaa 2300

 aaaaaaaaaa 2310

<210> 184
<211> 349
<212> PRT
<213> Homo sapien

<400> 184
 Met Ser Lys Ser Lys Asp Asp Ala Pro His Glu Leu Glu Ser Gln
   1               5                  10                  15

 Phe Ile Leu Arg Leu Pro Pro Glu Tyr Ala Ser Thr Val Arg Arg
                  20                  25                  30

 Ala Val Gln Ser Gly His Val Asn Leu Lys Asp Arg Leu Thr Ile
                  35                  40                  45

 Glu Leu His Pro Asp Gly Arg His Gly Ile Val Arg Val Asp Arg
                  50                  55                  60

 Val Pro Leu Ala Ser Lys Leu Val Asp Leu Pro Cys Val Met Glu
                  65                  70                  75

 Ser Leu Lys Thr Ile Asp Lys Lys Thr Phe Tyr Lys Thr Ala Asp
                  80                  85                  90

 Ile Cys Gln Met Leu Val Ser Thr Val Asp Gly Asp Leu Tyr Pro
                  95                 100                 105

 Pro Val Glu Glu Pro Val Ala Ser Thr Asp Pro Lys Ala Ser Lys
                 110                 115                 120

 Lys Lys Asp Lys Asp Lys Glu Lys Lys Phe Ile Trp Asn His Gly
                 125                 130                 135

 Ile Thr Leu Pro Leu Lys Asn Val Arg Lys Arg Arg Phe Arg Lys
                 140                 145                 150

 Thr Ala Lys Lys Lys Tyr Ile Glu Ser Pro Asp Val Glu Lys Glu
                 155                 160                 165

 Val Lys Arg Leu Leu Ser Thr Asp Ala Glu Ala Val Ser Thr Arg
                 170                 175                 180

 Trp Glu Ile Ile Ala Glu Asp Glu Thr Lys Glu Ala Glu Asn Gln
                 185                 190                 195

 Gly Leu Asp Ile Ser Ser Pro Gly Met Ser Gly His Arg Gln Gly
                 200                 205                 210

 His Asp Ser Leu Glu His Asp Glu Leu Arg Glu Ile Phe Asn Asp
                 215                 220                 225

 Leu Ser Ser Ser Ser Glu Asp Glu Asp Glu Thr Gln His Gln Asp
                 230                 235                 240

 Glu Glu Asp Ile Asn Ile Ile Asp Thr Glu Glu Asp Leu Glu Arg
                 245                 250                 255

 Gln Leu Gln Asp Lys Leu Asn Glu Ser Asp Glu Gln His Gln Glu
                 260                 265                 270

 Asn Glu Gly Thr Asn Gln Leu Val Met Gly Ile Gln Lys Gln Ile
                 275                 280                 285

 Asp Asn Met Lys Gly Lys Leu Gln Glu Thr Gln Asp Arg Ala Lys
                 290                 295                 300

 Arg Gln Glu Asp Leu Ile Met Lys Val Glu Asn Leu Ala Leu Lys
                 305                 310                 315

 Asn Arg Phe Gln Ala Val Leu Asp Glu Leu Lys Gln Lys Glu Asp
                 320                 325                 330

 Arg Glu Lys Glu Gln Leu Ser Ser Leu Gln Glu Glu Leu Glu Ser
                 335                 340                 345

 Leu Leu Glu Lys


<210> 185
<211> 4170
<212> DNA
<213> Homo sapien

<400> 185
 cgcgggtctg tggagagccg ggtgcgagcg gcggcagcac gaggggaaaa 50

 gagctgagcg gagaccaaag tcagccggga gacagtgggt ctgtgagaga 100

 ccgaatagag gggctggggc cacgagcgcc attgacaagc aatggggaag 150

 aaacagaaaa acaagagcga agacagcacc aaggatgaca ttgatcttga 200

 tgccttggct gcagaaatag aaggagctgg tgctgccaaa gaacaggagc 250

 ctcaaaagtc aaaagggaaa aagaaaaaag agaaaaaaaa gcaggacttt 300

 gatgaagatg atatcctgaa agaactggaa gaattgtctt tggaagctca 350

 aggcatcaaa gctgacagag aaactgttgc agtgaagcca acagaaaaca 400

 atgaagagga attcacctca aaagataaaa aaaagaaagg acagaagggc 450

 aaaaaacaga gttttgatga taatgatagc gaagaattgg aagataaaga 500

 ttcaaaatca aaaaagactg caaaaccgaa agtggaaatg tactctggga 550

 gtgatgatga tgatgatttt aacaaacttc ctaaaaaagc taaagggaaa 600

 gctcaaaaat caaataagaa gtgggatggg tcagaggagg atgaggataa 650

 cagtaaaaaa attaaagagc gttcaagaat aaattcttct ggtgaaagtg 700

 gtgatgaatc agatgaattt ttgcaatcta gaaaaggaca gaaaaaaaat 750

 cagaaaaaca agccaggtcc taacatagaa agtgggaatg aagatgatga 800

 cgcctccttc aaaattaaga cagtggccca aaagaaggca gaaaagaagg 850

 agcgcgagag aaaaaagcga gatgaagaaa aagcgaaact gcggaagctg 900

 aaagaaaaag aagagttaga aacaggtaaa aaggatcaga gtaaacaaaa 950

 ggaatctcaa aggaaatttg aagaagaaac tgtaaaatcc aaagtgactg 1000

 ttgatactgg agtaattcct gcctctgaag agaaagcaga gactcccaca 1050

 gctgcagaag atgacaatga aggagacaaa aagaagaaag ataagaagaa 1100

 aaagaaagga gaaaaggaag aaaaagagaa agagaagaaa aaaggaccta 1150

 gcaaagccac tgttaaagct atgcaagaag ctctggctaa gcttaaagag 1200

 gaagaagaaa gacagaagag agaagaggaa gaacgtataa aacggcttga 1250

 agaattagaa gccaagcgta aagaagagga acgattggaa caagaaaaaa 1300

 gagaaaggaa aaagcaaaaa gaaaaagaaa gaaaagaacg cttgaaaaaa 1350

 gaagggaaac ttttaactaa atcccagaga gaagccagag ccagagccga 1400

 agctactctt aaactgctac aagctcaggg tgttgaagtg ccatcaaaag 1450

 actctttgcc aaagaagagg ccaatttatg aagataaaaa gaggaaaaaa 1500

 ataccacagc agctagaaag taaagaagtg tctgaatcaa tggaattatg 1550

 tgctgctgta gaagttatgg aacaaggagt accagaaaag gaagagacac 1600

 cacctcctgt tgaaccagaa gaagaagaag atactgagga tgctggattg 1650

 gatgattggg aagctatggc cagtgatgag gagacagaaa aagtagaagg 1700

 aaacacagtt catatagaag taaaagaaaa ccctgaagag gaggaggagg 1750

 aggaagaaga ggaagaagaa gatgaagaaa gtgaagaaga ggaggaagag 1800

 gagggagaaa gtgaaggcag tgaaggtgat gaggaagatg aaaaggtgtc 1850

 agatgagaag gattcaggga agacattaga taaaaagcca agtaaagaaa 1900

 tgagctcaga ttctgaatat gactctgatg atgatcggac taaagaagaa 1950

 agggcttatg acaaagcaaa acggaggatt gagaaacggc gacttgaaca 2000

 tagtaaaaat gtaaacaccg aaaagctaag agcccctatt atctgcgtac 2050

 ttgggcatgt ggacacaggg aagacaaaaa ttctagataa gctccgtcac 2100

 acacatgtac aagacggtga agcaggtggt atcacacaac aaatttgggc 2150

 caccaatgtt cctcttgaag ctattaatga acagactaag atgattaaaa 2200

 attttgatag agagaatgta cggattccag gaatgctaat tattgatact 2250

 cctgggcatg aatctttcag taatctgaga aatagaggaa gctctctttg 2300

 tgacattgcc attttagttg ttgatattat gcatggtttg gagccccaga 2350

 caattgagtc tatcaacctt ctcaaatcta aaaaatgtcc cttcattgtt 2400

 gcactcaata agattgatag gttatatgat tggaaaaaga gtcctgactc 2450

 tgatgtggct gctactttaa agaagcagaa aaagaataca aaagatgaat 2500

 ttgaggagcg agcaaaggct attattgtag aatttgcaca gcagggtttg 2550

 aatgctgctt tgttttatga gaataaagat ccccgcactt ttgtgtcttt 2600

 ggtacctacc tctgcacata ctggtgatgg catgggaagt ctgatctacc 2650

 ttcttgtaga gttaactcag accatgttga gcaagagact tgcacactgt 2700

 gaagagctga gagcacaggt gatggaggtt aaagctctcc cggggatggg 2750

 caccactata gatgtcattt tgatcaatgg gcgtttgaag gaaggagata 2800

 caatcattgt tcctggagta gaagggccca ttgtaactca gattcgaggc 2850

 ctcctgttac ctcctcctat gaaggaatta cgagtgaaga accagtatga 2900

 aaagcataaa gaagtagaag cagctcaggg ggtaaagatt cttggaaaag 2950

 acctggagaa aacattggct ggtttacccc tccttgtggc ttataaagaa 3000

 gatgaaatcc ctgttcttaa agatgaattg atccatgagt taaagcagac 3050

 actaaatgct atcaaattag aagaaaaagg agtctatgtc caggcatcta 3100

 cactgggttc tttggaagct ctactggaat ttctgaaaac atcagaagtg 3150

 ccctatgcag gaattaacat tggcccagtg cataaaaaag atgttatgaa 3200

 ggcttcagtg atgttggaac atgaccctca gtatgcagta attttggcct 3250

 tcgatgtgag aattgaacga gatgcacaag aaatggctga tagtttagga 3300

 gttagaattt ttagtgcaga aattatttat catttatttg atgcctttac 3350

 aaaatataga caagactaca agaaacagaa acaagaagaa tttaagcaca 3400

 tagcagtatt tccctgcaag ataaaaatcc tccctcagta catttttaat 3450

 tctcgagatc cgatagtgat gggggtgacg gtggaagcag gtcaggtgaa 3500

 acaggggaca cccatgtgtg tcccaagcaa aaattttgtt gacatcggaa 3550

 tagtaacaag tattgaaata aaccataaac aagtggatgt tgcaaaaaaa 3600

 ggacaagaag tttgtgtaaa aatagaacct atccctggtg agtcacccaa 3650

 aatgtttgga agacattttg aagctacaga tattcttgtt agtaagatca 3700

 gccggcagtc cattgatgca ctcaaagact ggttcagaga tgaaatgcag 3750

 aagagtgact ggcagcttat tgtggagctg aagaaagtat ttgaaatcat 3800

 ctaatttttt cacatggagc aggaactgga gtaaatgcaa tactgtgttg 3850

 taatatccca acaaaaatca gacaaaaaat ggaacagacg tatttggaca 3900

 ctgatggact taagtatgga aggaagaaaa ataggtgtat aaaatgtttt 3950

 ccatgagaaa ccaagaaact tacactggtt tgacagtggt cagttacatg 4000

 tccccacagt tccaatgtgc ctgttcactc acctctccct tccccaaccc 4050

 ttctctactt ggctgctgtt ttaaagtttg cccttcccca aatttggatt 4100

 tttattacag agtctaaagc tctttcgatt ttatactgat taaatcagta 4150

 ctgcagtatt tgattaacca 4170

<210> 186
<211> 1220
<212> PRT
<213> Homo sapien

<400> 186
 Met Gly Lys Lys Gln Lys Asn Lys Ser Glu Asp Ser Thr Lys Asp
   1               5                  10                  15

 Asp Ile Asp Leu Asp Ala Leu Ala Ala Glu Ile Glu Gly Ala Gly
                  20                  25                  30

 Ala Ala Lys Glu Gln Glu Pro Gln Lys Ser Lys Gly Lys Lys Lys
                  35                  40                  45

 Lys Glu Lys Lys Lys Gln Asp Phe Asp Glu Asp Asp Ile Leu Lys
                  50                  55                  60

 Glu Leu Glu Glu Leu Ser Leu Glu Ala Gln Gly Ile Lys Ala Asp
                  65                  70                  75

 Arg Glu Thr Val Ala Val Lys Pro Thr Glu Asn Asn Glu Glu Glu
                  80                  85                  90

 Phe Thr Ser Lys Asp Lys Lys Lys Lys Gly Gln Lys Gly Lys Lys
                  95                 100                 105

 Gln Ser Phe Asp Asp Asn Asp Ser Glu Glu Leu Glu Asp Lys Asp
                 110                 115                 120

 Ser Lys Ser Lys Lys Thr Ala Lys Pro Lys Val Glu Met Tyr Ser
                 125                 130                 135

 Gly Ser Asp Asp Asp Asp Asp Phe Asn Lys Leu Pro Lys Lys Ala
                 140                 145                 150

 Lys Gly Lys Ala Gln Lys Ser Asn Lys Lys Trp Asp Gly Ser Glu
                 155                 160                 165

 Glu Asp Glu Asp Asn Ser Lys Lys Ile Lys Glu Arg Ser Arg Ile
                 170                 175                 180

 Asn Ser Ser Gly Glu Ser Gly Asp Glu Ser Asp Glu Phe Leu Gln
                 185                 190                 195

 Ser Arg Lys Gly Gln Lys Lys Asn Gln Lys Asn Lys Pro Gly Pro
                 200                 205                 210

 Asn Ile Glu Ser Gly Asn Glu Asp Asp Asp Ala Ser Phe Lys Ile
                 215                 220                 225

 Lys Thr Val Ala Gln Lys Lys Ala Glu Lys Lys Glu Arg Glu Arg
                 230                 235                 240

 Lys Lys Arg Asp Glu Glu Lys Ala Lys Leu Arg Lys Leu Lys Glu
                 245                 250                 255

 Lys Glu Glu Leu Glu Thr Gly Lys Lys Asp Gln Ser Lys Gln Lys
                 260                 265                 270

 Glu Ser Gln Arg Lys Phe Glu Glu Glu Thr Val Lys Ser Lys Val
                 275                 280                 285

 Thr Val Asp Thr Gly Val Ile Pro Ala Ser Glu Glu Lys Ala Glu
                 290                 295                 300

 Thr Pro Thr Ala Ala Glu Asp Asp Asn Glu Gly Asp Lys Lys Lys
                 305                 310                 315

 Lys Asp Lys Lys Lys Lys Lys Gly Glu Lys Glu Glu Lys Glu Lys
                 320                 325                 330

 Glu Lys Lys Lys Gly Pro Ser Lys Ala Thr Val Lys Ala Met Gln
                 335                 340                 345

 Glu Ala Leu Ala Lys Leu Lys Glu Glu Glu Glu Arg Gln Lys Arg
                 350                 355                 360

 Glu Glu Glu Glu Arg Ile Lys Arg Leu Glu Glu Leu Glu Ala Lys
                 365                 370                 375

 Arg Lys Glu Glu Glu Arg Leu Glu Gln Glu Lys Arg Glu Arg Lys
                 380                 385                 390

 Lys Gln Lys Glu Lys Glu Arg Lys Glu Arg Leu Lys Lys Glu Gly
                 395                 400                 405

 Lys Leu Leu Thr Lys Ser Gln Arg Glu Ala Arg Ala Arg Ala Glu
                 410                 415                 420

 Ala Thr Leu Lys Leu Leu Gln Ala Gln Gly Val Glu Val Pro Ser
                 425                 430                 435

 Lys Asp Ser Leu Pro Lys Lys Arg Pro Ile Tyr Glu Asp Lys Lys
                 440                 445                 450

 Arg Lys Lys Ile Pro Gln Gln Leu Glu Ser Lys Glu Val Ser Glu
                 455                 460                 465

 Ser Met Glu Leu Cys Ala Ala Val Glu Val Met Glu Gln Gly Val
                 470                 475                 480

 Pro Glu Lys Glu Glu Thr Pro Pro Pro Val Glu Pro Glu Glu Glu
                 485                 490                 495

 Glu Asp Thr Glu Asp Ala Gly Leu Asp Asp Trp Glu Ala Met Ala
                 500                 505                 510

 Ser Asp Glu Glu Thr Glu Lys Val Glu Gly Asn Thr Val His Ile
                 515                 520                 525

 Glu Val Lys Glu Asn Pro Glu Glu Glu Glu Glu Glu Glu Glu Glu
                 530                 535                 540

 Glu Glu Glu Asp Glu Glu Ser Glu Glu Glu Glu Glu Glu Glu Gly
                 545                 550                 555

 Glu Ser Glu Gly Ser Glu Gly Asp Glu Glu Asp Glu Lys Val Ser
                 560                 565                 570

 Asp Glu Lys Asp Ser Gly Lys Thr Leu Asp Lys Lys Pro Ser Lys
                 575                 580                 585

 Glu Met Ser Ser Asp Ser Glu Tyr Asp Ser Asp Asp Asp Arg Thr
                 590                 595                 600

 Lys Glu Glu Arg Ala Tyr Asp Lys Ala Lys Arg Arg Ile Glu Lys
                 605                 610                 615

 Arg Arg Leu Glu His Ser Lys Asn Val Asn Thr Glu Lys Leu Arg
                 620                 625                 630

 Ala Pro Ile Ile Cys Val Leu Gly His Val Asp Thr Gly Lys Thr
                 635                 640                 645

 Lys Ile Leu Asp Lys Leu Arg His Thr His Val Gln Asp Gly Glu
                 650                 655                 660

 Ala Gly Gly Ile Thr Gln Gln Ile Trp Ala Thr Asn Val Pro Leu
                 665                 670                 675

 Glu Ala Ile Asn Glu Gln Thr Lys Met Ile Lys Asn Phe Asp Arg
                 680                 685                 690

 Glu Asn Val Arg Ile Pro Gly Met Leu Ile Ile Asp Thr Pro Gly
                 695                 700                 705

 His Glu Ser Phe Ser Asn Leu Arg Asn Arg Gly Ser Ser Leu Cys
                 710                 715                 720

 Asp Ile Ala Ile Leu Val Val Asp Ile Met His Gly Leu Glu Pro
                 725                 730                 735

 Gln Thr Ile Glu Ser Ile Asn Leu Leu Lys Ser Lys Lys Cys Pro
                 740                 745                 750

 Phe Ile Val Ala Leu Asn Lys Ile Asp Arg Leu Tyr Asp Trp Lys
                 755                 760                 765

 Lys Ser Pro Asp Ser Asp Val Ala Ala Thr Leu Lys Lys Gln Lys
                 770                 775                 780

 Lys Asn Thr Lys Asp Glu Phe Glu Glu Arg Ala Lys Ala Ile Ile
                 785                 790                 795

 Val Glu Phe Ala Gln Gln Gly Leu Asn Ala Ala Leu Phe Tyr Glu
                 800                 805                 810

 Asn Lys Asp Pro Arg Thr Phe Val Ser Leu Val Pro Thr Ser Ala
                 815                 820                 825

 His Thr Gly Asp Gly Met Gly Ser Leu Ile Tyr Leu Leu Val Glu
                 830                 835                 840

 Leu Thr Gln Thr Met Leu Ser Lys Arg Leu Ala His Cys Glu Glu
                 845                 850                 855

 Leu Arg Ala Gln Val Met Glu Val Lys Ala Leu Pro Gly Met Gly
                 860                 865                 870

 Thr Thr Ile Asp Val Ile Leu Ile Asn Gly Arg Leu Lys Glu Gly
                 875                 880                 885

 Asp Thr Ile Ile Val Pro Gly Val Glu Gly Pro Ile Val Thr Gln
                 890                 895                 900

 Ile Arg Gly Leu Leu Leu Pro Pro Pro Met Lys Glu Leu Arg Val
                 905                 910                 915

 Lys Asn Gln Tyr Glu Lys His Lys Glu Val Glu Ala Ala Gln Gly
                 920                 925                 930

 Val Lys Ile Leu Gly Lys Asp Leu Glu Lys Thr Leu Ala Gly Leu
                 935                 940                 945

 Pro Leu Leu Val Ala Tyr Lys Glu Asp Glu Ile Pro Val Leu Lys
                 950                 955                 960

 Asp Glu Leu Ile His Glu Leu Lys Gln Thr Leu Asn Ala Ile Lys
                 965                 970                 975

 Leu Glu Glu Lys Gly Val Tyr Val Gln Ala Ser Thr Leu Gly Ser
                 980                 985                 990

 Leu Glu Ala Leu Leu Glu Phe Leu Lys Thr Ser Glu Val Pro Tyr
                 995                1000                1005

 Ala Gly Ile Asn Ile Gly Pro Val His Lys Lys Asp Val Met Lys
                1010                1015                1020

 Ala Ser Val Met Leu Glu His Asp Pro Gln Tyr Ala Val Ile Leu
                1025                1030                1035

 Ala Phe Asp Val Arg Ile Glu Arg Asp Ala Gln Glu Met Ala Asp
                1040                1045                1050

 Ser Leu Gly Val Arg Ile Phe Ser Ala Glu Ile Ile Tyr His Leu
                1055                1060                1065

 Phe Asp Ala Phe Thr Lys Tyr Arg Gln Asp Tyr Lys Lys Gln Lys
                1070                1075                1080

 Gln Glu Glu Phe Lys His Ile Ala Val Phe Pro Cys Lys Ile Lys
                1085                1090                1095

 Ile Leu Pro Gln Tyr Ile Phe Asn Ser Arg Asp Pro Ile Val Met
                1100                1105                1110

 Gly Val Thr Val Glu Ala Gly Gln Val Lys Gln Gly Thr Pro Met
                1115                1120                1125

 Cys Val Pro Ser Lys Asn Phe Val Asp Ile Gly Ile Val Thr Ser
                1130                1135                1140

 Ile Glu Ile Asn His Lys Gln Val Asp Val Ala Lys Lys Gly Gln
                1145                1150                1155

 Glu Val Cys Val Lys Ile Glu Pro Ile Pro Gly Glu Ser Pro Lys
                1160                1165                1170

 Met Phe Gly Arg His Phe Glu Ala Thr Asp Ile Leu Val Ser Lys
                1175                1180                1185

 Ile Ser Arg Gln Ser Ile Asp Ala Leu Lys Asp Trp Phe Arg Asp
                1190                1195                1200

 Glu Met Gln Lys Ser Asp Trp Gln Leu Ile Val Glu Leu Lys Lys
                1205                1210                1215

 Val Phe Glu Ile Ile
                1220

<210> 187
<211> 1877
<212> DNA
<213> Homo sapien

<400> 187
 cgcccccaga gtctggcttt ccgcggctgc ccgcctcgcg cgtcttccct 50

 gcccgggtct cctcgctgtc gccgccgctg ccacaccatg gccttcgtca 100

 ccaggcagtt catgcgttcc gtgtcctcct cgtccaccgc ctcggcctcg 150

 gccaagaaga taatcgtcaa gcacgtgacg gtcatcggcg gcgggctgat 200

 gggcgccggc attgcccagg ttgctgcagc aactggtcac acagtagtgt 250

 tggtagacca gacagaggac atcctggcaa aatccaaaaa gggaattgag 300

 gaaagcctta ggaaagtggc aaagaagaag tttgcagaaa accctaaggc 350

 cggcgatgaa tttgtggaga agaccctgag caccatagcg accagcacgg 400

 atgcagcctc cgttgtccac agcacagact tggtggtgga agccatcgtg 450

 gagaatctga aggtgaaaaa cgagctcttc aaaaggctgg acaagtttgc 500

 tgctgaacat acaatctttg ccagcaacac ttcctccttg catattacaa 550

 gcatagctaa tgccaccacc agacaagacc gattcgctgg cctccatttc 600

 ttcaacccag tgcctgtcat gaaacttgtg gaggtcatta aaacaccaat 650

 gaccagccag aagacatttg aatctttggt agactttagc aaagccctag 700

 gaaagcatcc tgtttcttgc aaggacactc ctgggtttat tgtgaaccgc 750

 ctcctggttc catacctcat ggaagcaatc aggctgtatg aacgaggtga 800

 cgcatccaaa gaagacattg acactgctat gaaattagga gccggttacc 850

 ccatgggccc atttgagctt ctagattatg tcggactgga tactacgaag 900

 ttcatcgtgg atgggtggca tgaaatggat gcagagaacc cattacatca 950

 gcccagccca tccttaaata agctggtagc agagaacaag ttcggcaaga 1000

 agactggaga aggattttac aaatacaagt gatgtgcagc ttctccggct 1050

 ctgagaagaa cacctgagag cgctttccag ccagtgcccc gagtgcctgt 1100

 gggaatgctc tttggtcaga cattccctca cacagtacag tttaataaat 1150

 gtgcattttg attgtaatct atcgaagtga ttattacacc agttacagca 1200

 gtaatagatt ctccattaag aaataattcc cttttttagt ctgttcattt 1250

 ctgtgtattt tctaaacagc tttacaccct tggtgccttg gagcaaacat 1300

 gttttttgaa ccttgtcatt tttgtgaaga attgcctaga ttccttctct 1350

 catcaacggg aaagtacttc ctctgagagt gcgagtgcac catgctcact 1400

 gttgctgcgt gggagagtca caagccactg gcaagcaagt ggtatagtct 1450

 gtgaagcact gcagcgagca gcacctggat cttgccttta taagaacatt 1500

 ttactacctg cagctttgag tcttgcccta cattttgggc atgacataag 1550

 atgtgtcttt attcagctcg tcgtgaagat gctgctgctg aatgggtcag 1600

 catatctctg tttgcatggt ttgcaggagg tcggttttca tggtcattca 1650

 gttccacaga tctgaatgat tactgtctgt ctgtgtcttt tttccatgag 1700

 aaatcactgt tgcaaattgc ctataaattg actctactaa aataacaatg 1750

 tttcagtctg aaaatttgaa ttgaaaaaaa tgtataatat aaaattgtaa 1800

 tacactcaaa tgattataaa agtaaaagtt ggtaatttag gcaaaaaaaa 1850

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 1877

<210> 188
<211> 314
<212> PRT
<213> Homo sapien

<400> 188
 Met Ala Phe Val Thr Arg Gln Phe Met Arg Ser Val Ser Ser Ser
   1               5                  10                  15

 Ser Thr Ala Ser Ala Ser Ala Lys Lys Ile Ile Val Lys His Val
                  20                  25                  30

 Thr Val Ile Gly Gly Gly Leu Met Gly Ala Gly Ile Ala Gln Val
                  35                  40                  45

 Ala Ala Ala Thr Gly His Thr Val Val Leu Val Asp Gln Thr Glu
                  50                  55                  60

 Asp Ile Leu Ala Lys Ser Lys Lys Gly Ile Glu Glu Ser Leu Arg
                  65                  70                  75

 Lys Val Ala Lys Lys Lys Phe Ala Glu Asn Pro Lys Ala Gly Asp
                  80                  85                  90

 Glu Phe Val Glu Lys Thr Leu Ser Thr Ile Ala Thr Ser Thr Asp
                  95                 100                 105

 Ala Ala Ser Val Val His Ser Thr Asp Leu Val Val Glu Ala Ile
                 110                 115                 120

 Val Glu Asn Leu Lys Val Lys Asn Glu Leu Phe Lys Arg Leu Asp
                 125                 130                 135

 Lys Phe Ala Ala Glu His Thr Ile Phe Ala Ser Asn Thr Ser Ser
                 140                 145                 150

 Leu His Ile Thr Ser Ile Ala Asn Ala Thr Thr Arg Gln Asp Arg
                 155                 160                 165

 Phe Ala Gly Leu His Phe Phe Asn Pro Val Pro Val Met Lys Leu
                 170                 175                 180

 Val Glu Val Ile Lys Thr Pro Met Thr Ser Gln Lys Thr Phe Glu
                 185                 190                 195

 Ser Leu Val Asp Phe Ser Lys Ala Leu Gly Lys His Pro Val Ser
                 200                 205                 210

 Cys Lys Asp Thr Pro Gly Phe Ile Val Asn Arg Leu Leu Val Pro
                 215                 220                 225

 Tyr Leu Met Glu Ala Ile Arg Leu Tyr Glu Arg Gly Asp Ala Ser
                 230                 235                 240

 Lys Glu Asp Ile Asp Thr Ala Met Lys Leu Gly Ala Gly Tyr Pro
                 245                 250                 255

 Met Gly Pro Phe Glu Leu Leu Asp Tyr Val Gly Leu Asp Thr Thr
                 260                 265                 270

 Lys Phe Ile Val Asp Gly Trp His Glu Met Asp Ala Glu Asn Pro
                 275                 280                 285

 Leu His Gln Pro Ser Pro Ser Leu Asn Lys Leu Val Ala Glu Asn
                 290                 295                 300

 Lys Phe Gly Lys Lys Thr Gly Glu Gly Phe Tyr Lys Tyr Lys
                 305                 310

<210> 189
<211> 2015
<212> DNA
<213> Homo sapien

<400> 189
 tcgctgcgaa ggacatttgg gctgtgtgtg cgacgcgggt cggaggggca 50

 gtcgggggaa ccgcgaagaa gccgaggagc ccggagcccc gcgtgacgct 100

 cctctctcag tccaaaagcg gcttttggtt cggcgcagag agacccgggg 150

 gtctagcttt tcctcgaaaa gcgccgccct gcccttggcc ccgagaacag 200

 acaaagagca ccgcagggcc gatcacgctg ggggcgctga ggccggccat 250

 ggtcatggaa gtgggcaccc tggacgctgg aggcctgcgg gcgctgctgg 300

 gggagcgagc ggcgcaatgc ctgctgctgg actgccgctc cttcttcgct 350

 ttcaacgccg gccacatcgc cggctctgtc aacgtgcgct tcagcaccat 400

 cgtgcggcgc cgggccaagg gcgccatggg cctggagcac atcgtgccca 450

 acgccgagct ccgcggccgc ctgctggccg gcgcctacca cgccgtggtg 500

 ttgctggacg agcgcagcgc cgccctggac ggcgccaagc gcgacggcac 550

 cctggccctg gcggccggcg cgctctgccg cgaggcgcgc gccgcgcaag 600

 tcttcttcct caaaggagga tacgaagcgt tttcggcttc ctgcccggag 650

 ctgtgcagca aacagtcgac ccccatgggg ctcagccttc ccctgagtac 700

 tagcgtccct gacagcgcgg aatctgggtg cagttcctgc agtaccccac 750

 tctacgatca gggtggcccg gtggaaatcc tgccctttct gtacctgggc 800

 agtgcgtatc acgcttcccg caaggacatg ctggatgcct tgggcataac 850

 tgccttgatc aacgtctcag ccaattgtcc caaccatttt gagggtcact 900

 accagtacaa gagcatccct gtggaggaca accacaaggc agacatcagc 950

 tcctggttca acgaggccat tgacttcata gactccatca agaatgctgg 1000

 aggaagggtg tttgtccact gccaggcagg catttcccgg tcagccacca 1050

 tctgccttgc ttaccttatg aggactaatc gagtcaagct ggacgaggcc 1100

 tttgagtttg tgaagcagag gcgaagcatc atctctccca acttcagctt 1150

 catgggccag ctgctgcagt ttgagtccca ggtgctggct ccgcactgtt 1200

 cggcagaggc tgggagcccc gccatggctg tgctcgaccg aggcacctcc 1250

 accaccaccg tgttcaactt ccccgtctcc atccctgtcc actccacgaa 1300

 cagtgcgctg agctaccttc agagccccat tacgacctct cccagctgct 1350

 gaaaggccac gggaggtgag gctcttcaca tcccattggg actccatgct 1400

 ccttgagagg agaaatgcaa taactctggg aggggctcga gagggctggt 1450

 ccttatttat ttaacttcac ccgagttcct ctgggtttct aagcagttat 1500

 ggtgatgact tagcgtcaag acatttgctg aactcagcac attcgggacc 1550

 aatatatagt gggtacatca agtccatctg acaaaatggg gcagaagaga 1600

 aaggactcag tgtgtgatcc ggtttctttt tgctcgcccc tgttttttgt 1650

 agaatctctt catgcttgac atacctacca gtattattcc cgacgacaca 1700

 tatacatatg agaatatacc ttatttattt ttgtgtaggt gtctgccttc 1750

 acaaatgtca ttgtctactc ctagaagaac caaatacctc aatttttgtt 1800

 tttgagtact gtactatcct gtaaatatat cttaagcagg tttgttttca 1850

 gcactgatgg aaaataccag tgttgggttt ttttttagtt gccaacagtt 1900

 gtatgtttgc tgattattta tgacctgaaa taatatattt cttcttctaa 1950

 gaagacattt tgttacataa ggatgacttt tttatacaat ggaataaatt 2000

 atggcatttc tattg 2015

<210> 190
<211> 367
<212> PRT
<213> Homo sapien

<400> 190
 Met Val Met Glu Val Gly Thr Leu Asp Ala Gly Gly Leu Arg Ala
   1               5                  10                  15

 Leu Leu Gly Glu Arg Ala Ala Gln Cys Leu Leu Leu Asp Cys Arg
                  20                  25                  30

 Ser Phe Phe Ala Phe Asn Ala Gly His Ile Ala Gly Ser Val Asn
                  35                  40                  45

 Val Arg Phe Ser Thr Ile Val Arg Arg Arg Ala Lys Gly Ala Met
                  50                  55                  60

 Gly Leu Glu His Ile Val Pro Asn Ala Glu Leu Arg Gly Arg Leu
                  65                  70                  75

 Leu Ala Gly Ala Tyr His Ala Val Val Leu Leu Asp Glu Arg Ser
                  80                  85                  90

 Ala Ala Leu Asp Gly Ala Lys Arg Asp Gly Thr Leu Ala Leu Ala
                  95                 100                 105

 Ala Gly Ala Leu Cys Arg Glu Ala Arg Ala Ala Gln Val Phe Phe
                 110                 115                 120

 Leu Lys Gly Gly Tyr Glu Ala Phe Ser Ala Ser Cys Pro Glu Leu
                 125                 130                 135

 Cys Ser Lys Gln Ser Thr Pro Met Gly Leu Ser Leu Pro Leu Ser
                 140                 145                 150

 Thr Ser Val Pro Asp Ser Ala Glu Ser Gly Cys Ser Ser Cys Ser
                 155                 160                 165

 Thr Pro Leu Tyr Asp Gln Gly Gly Pro Val Glu Ile Leu Pro Phe
                 170                 175                 180

 Leu Tyr Leu Gly Ser Ala Tyr His Ala Ser Arg Lys Asp Met Leu
                 185                 190                 195

 Asp Ala Leu Gly Ile Thr Ala Leu Ile Asn Val Ser Ala Asn Cys
                 200                 205                 210

 Pro Asn His Phe Glu Gly His Tyr Gln Tyr Lys Ser Ile Pro Val
                 215                 220                 225

 Glu Asp Asn His Lys Ala Asp Ile Ser Ser Trp Phe Asn Glu Ala
                 230                 235                 240

 Ile Asp Phe Ile Asp Ser Ile Lys Asn Ala Gly Gly Arg Val Phe
                 245                 250                 255

 Val His Cys Gln Ala Gly Ile Ser Arg Ser Ala Thr Ile Cys Leu
                 260                 265                 270

 Ala Tyr Leu Met Arg Thr Asn Arg Val Lys Leu Asp Glu Ala Phe
                 275                 280                 285

 Glu Phe Val Lys Gln Arg Arg Ser Ile Ile Ser Pro Asn Phe Ser
                 290                 295                 300

 Phe Met Gly Gln Leu Leu Gln Phe Glu Ser Gln Val Leu Ala Pro
                 305                 310                 315

 His Cys Ser Ala Glu Ala Gly Ser Pro Ala Met Ala Val Leu Asp
                 320                 325                 330

 Arg Gly Thr Ser Thr Thr Thr Val Phe Asn Phe Pro Val Ser Ile
                 335                 340                 345

 Pro Val His Ser Thr Asn Ser Ala Leu Ser Tyr Leu Gln Ser Pro
                 350                 355                 360

 Ile Thr Thr Ser Pro Ser Cys
                 365

<210> 191
<211> 1136
<212> DNA
<213> Homo sapien

<400> 191
 cgggtgctgg gggctcgaga accgagcgga gctggttgag ccttcaaagt 50

 cctaaaacgc gcggccgtgg gttcggggtt tattgattga attccgccgg 100

 cgcgggagcc tctgcagaga gagagcgcga gagatggaga tgggcagacg 150

 gattcattta gagctgcgga acaggacgcc ctctgatgtg aaagaacttg 200

 tcctggacaa cagtcggtcg aatgaaggca aactcgaagg cctcacagat 250

 gaatttgaag aactggaatt cttaagtaca atcaacgtag gcctcacctc 300

 aatcgcaaac ttaccaaagt taaacaaact taagaagctt gaactaagcg 350

 ataacagagt ctcagggggc ctggaagtat tggcagaaaa gtgtccgaac 400

 ctcacgcatc taaatttaag tggcaacaaa attaaagacc tcagcacaat 450

 agagccactg aaaaagttag aaaacctcaa gagcttagac cttttcaatt 500

 gcgaggtaac caacctgaac gactaccgag aaaatgtgtt caagctcctc 550

 ccgcaactca catatctcga cggctatgac cgggacgaca aggaggcccc 600

 tgactcggat gctgagggct acgtggaggg cctggatgat gaggaggagg 650

 atgaggatga ggaggagtat gatgaagatg ctcaggtagt ggaagacgag 700

 gaggacgagg atgaggagga ggaaggtgaa gaggaggacg tgagtggaga 750

 ggaggaggag gatgaagaag gttataacga tggagaggta gatgacgagg 800

 aagatgaaga agagcttggt gaagaagaaa ggggtcagaa gcgaaaacga 850

 gaacctgaag atgagggaga agatgatgac taagtggaat aacctatttt 900

 gaaaaattcc tattgtgatt tgactgtttt tacccatatc ccctctcccc 950

 cccccctcca atcctgcccc ctgaaactta tttttttctg attgtaacgt 1000

 tgctgtggga acgagagggg aagagtgtac tgggggttgc ggggggaggg 1050

 atggcgggtg ggggtggaat aaaatactat ttttactgcc actctttaaa 1100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 1136

<210> 192
<211> 249
<212> PRT
<213> Homo sapien

<400> 192
 Met Glu Met Gly Arg Arg Ile His Leu Glu Leu Arg Asn Arg Thr
   1               5                  10                  15

 Pro Ser Asp Val Lys Glu Leu Val Leu Asp Asn Ser Arg Ser Asn
                  20                  25                  30

 Glu Gly Lys Leu Glu Gly Leu Thr Asp Glu Phe Glu Glu Leu Glu
                  35                  40                  45

 Phe Leu Ser Thr Ile Asn Val Gly Leu Thr Ser Ile Ala Asn Leu
                  50                  55                  60

 Pro Lys Leu Asn Lys Leu Lys Lys Leu Glu Leu Ser Asp Asn Arg
                  65                  70                  75

 Val Ser Gly Gly Leu Glu Val Leu Ala Glu Lys Cys Pro Asn Leu
                  80                  85                  90

 Thr His Leu Asn Leu Ser Gly Asn Lys Ile Lys Asp Leu Ser Thr
                  95                 100                 105

 Ile Glu Pro Leu Lys Lys Leu Glu Asn Leu Lys Ser Leu Asp Leu
                 110                 115                 120

 Phe Asn Cys Glu Val Thr Asn Leu Asn Asp Tyr Arg Glu Asn Val
                 125                 130                 135

 Phe Lys Leu Leu Pro Gln Leu Thr Tyr Leu Asp Gly Tyr Asp Arg
                 140                 145                 150

 Asp Asp Lys Glu Ala Pro Asp Ser Asp Ala Glu Gly Tyr Val Glu
                 155                 160                 165

 Gly Leu Asp Asp Glu Glu Glu Asp Glu Asp Glu Glu Glu Tyr Asp
                 170                 175                 180

 Glu Asp Ala Gln Val Val Glu Asp Glu Glu Asp Glu Asp Glu Glu
                 185                 190                 195

 Glu Glu Gly Glu Glu Glu Asp Val Ser Gly Glu Glu Glu Glu Asp
                 200                 205                 210

 Glu Glu Gly Tyr Asn Asp Gly Glu Val Asp Asp Glu Glu Asp Glu
                 215                 220                 225

 Glu Glu Leu Gly Glu Glu Glu Arg Gly Gln Lys Arg Lys Arg Glu
                 230                 235                 240

 Pro Glu Asp Glu Gly Glu Asp Asp Asp
                 245

<210> 193
<211> 2997
<212> DNA
<213> Homo sapien

<400> 193
 ggactgcggt ctcgggcagc aatggccgag aagcgcgaca cacgggactc 50

 cgaagcccag cggctccccg actccttcaa ggacagcccc agtaagggcc 100

 ttggaccttg cggatggatt ttggtggcgt tctcattctt attcaccgtt 150

 ataactttcc caatctcaat atggatgtgc ataaagatta taaaagagta 200

 tgaaagagcc atcatcttta gattgggtcg cattttacaa ggaggagcca 250

 aaggacctgg tttgtttttt attctgccat gcactgacag cttcatcaaa 300

 gtggacatga gaactatttc atttgatatt cctcctcagg agatcctgac 350

 aaaggattca gtgacaatta gcgtggatgg tgtggtctat taccgcgttc 400

 agaatgcaac cctggctgtg gcaaatatca ccaacgctga ctcagcaacc 450

 cgtcttttgg cacaaactac tctgaggaat gttctgggca ccaagaatct 500

 ttctcagatc ctctctgaca gagaagaaat tgcacacaac atgcagtcta 550

 ctctggatga tgccactgat gcctggggaa taaaggtgga gcgtgtggaa 600

 attaaggatg tgaaactacc tgtgcagctc cagagagcta tggctgcaga 650

 agcagaagcg tcccgcgagg cccgcgccaa ggttattgca gccgaaggag 700

 aaatgaatgc atccagggct ctgaaagaag cctccatggt catcactgaa 750

 tctcctgcag cccttcagct ccgatacctg cagacactga ccaccattgc 800

 tgctgagaaa aactcaacaa ttgtcttccc tctgcccata gatatgctgc 850

 aaggaatcat aggggcaaaa cacagccatc taggctagtg tagagatgag 900

 cgctagcctt ccaagcatga agtcggggac caaattagcc tttaactcat 950

 aaagagaggg tagggctttt ctttttccat atgtcaattg tggtgttccc 1000

 agaatgtata gcagttataa aaataggtga aagaattgtt agcttgtaaa 1050

 tactgagaga ttggtgattt atataaggta atctgttagt cttaaaatag 1100

 ttaaaagttt gtatttttag attattatgt agtaggttag atccctcttg 1150

 ttttgacttc cactgactca ttctgaaccc cctaagcacc caggccacag 1200

 gcaagaacct gggctgtaac tgccacctga caccgctgac tggctaaatg 1250

 ctttgcagaa agtgatgacc ttacaccaca accagcttct ccaggtcata 1300

 tgtgccttac ctccagaagt cttttttttt ttttttttct gagatggagt 1350

 ttcactcttg ttgcccaggc tggagtgcaa tagcatgatc tcggctcact 1400

 gcaacctccg cctcctgggt tcaagagatt ctcctgcctc agcctcccca 1450

 gtagctggga ttacaggctc atgccaccat gcccagctaa tttttgtatt 1500

 attattattg ttttttagta gagacggggt ttcaccatgt tggccaggct 1550

 agtcacgaac tcctaacctc aggtgatcca cccacctctg cctccaaagt 1600

 gctggattac aggctgagct accaccctgg tttggagagt cttaattaat 1650

 tgaaatttcc ctaatgttca tttattttct aaatccagcc gtgtttcaga 1700

 ataatcctta cttgagagta gccattttct tgtgtacttg tcagaactag 1750

 aggaaatagc caagactaat gaaaaacatt actctaaccc ttaaaagact 1800

 tttaaattca ctactagagt ggtcatttta aaaatacatc catgttttaa 1850

 cttattttga gcctttcttt tatgagtaaa tgattcctcc ttgttctgtc 1900

 tttcaaacca gctaaatatt tgtcacaaaa gtgacttttt tctcactgtt 1950

 gcctattttc atatatcagg ttttaaatag ttttaatttt ttaataaaat 2000

 ttttctctac gttctatatg caattgttat atatctattt gaatagctga 2050

 aggactaaaa tactttttta agagataact tcaggaaacc attatatttt 2100

 actatctgca tgctgttaac tgtggtacac tgtgaaatat gttgattaca 2150

 aacccattca ttacatagta taaggaattc acagtatatt gactatatag 2200

 tgtctaatga ctgggcagat actgtcaact tacaatatct atatagagag 2250

 gctttaaact taccttactc attctctatg atgtatgact tgatgctgaa 2300

 agaggaagct ggtcagctcc tcatggacaa caaattctta gtctataata 2350

 ttaggagaca tctctagttt tgcaaatgtc tgtgaatctg agcaacctgg 2400

 acttctgctt actggccaga aagctggcgg gtgacatttg taacatttcc 2450

 tctttgagac tctgagttca cctagagaag tctaagcata acagctttct 2500

 ttcccagcac gagcctttat agctctcttt agctcaacca ctctgtccat 2550

 ccagccaatg gatgtccttc cctgtaccca attcaagctt attttaggga 2600

 agccttgaaa ctaccatgta tctggctcta gctgagttat tgaggattga 2650

 gccagtgcaa cgttaaactc agtgcactta catttgattt aaatgatggt 2700

 tttatctgtt gtgtgaagtg gttcaccctt gaggaccagg agcctccata 2750

 tcctgactga aaaccttttc tgagacttag agtaacagta cttttggttc 2800

 cttgagttct cctgtctcca gatacctaaa tgaccttgac ttttctgcct 2850

 tgtgaattcg tagtccaatc agctgaaatt aaatcacttg ggagggacgc 2900

 atagaaggag ctctaggaac acagtgccag tgcagaagtt tctccaggtg 2950

 gcctcccttt ccaacaatgt acataataaa gtgtatgcac tttcact 2997

<210> 194
<211> 288
<212> PRT
<213> Homo sapien

<400> 194
 Met Ala Glu Lys Arg Asp Thr Arg Asp Ser Glu Ala Gln Arg Leu
   1               5                  10                  15

 Pro Asp Ser Phe Lys Asp Ser Pro Ser Lys Gly Leu Gly Pro Cys
                  20                  25                  30

 Gly Trp Ile Leu Val Ala Phe Ser Phe Leu Phe Thr Val Ile Thr
                  35                  40                  45

 Phe Pro Ile Ser Ile Trp Met Cys Ile Lys Ile Ile Lys Glu Tyr
                  50                  55                  60

 Glu Arg Ala Ile Ile Phe Arg Leu Gly Arg Ile Leu Gln Gly Gly
                  65                  70                  75

 Ala Lys Gly Pro Gly Leu Phe Phe Ile Leu Pro Cys Thr Asp Ser
                  80                  85                  90

 Phe Ile Lys Val Asp Met Arg Thr Ile Ser Phe Asp Ile Pro Pro
                  95                 100                 105

 Gln Glu Ile Leu Thr Lys Asp Ser Val Thr Ile Ser Val Asp Gly
                 110                 115                 120

 Val Val Tyr Tyr Arg Val Gln Asn Ala Thr Leu Ala Val Ala Asn
                 125                 130                 135

 Ile Thr Asn Ala Asp Ser Ala Thr Arg Leu Leu Ala Gln Thr Thr
                 140                 145                 150

 Leu Arg Asn Val Leu Gly Thr Lys Asn Leu Ser Gln Ile Leu Ser
                 155                 160                 165

 Asp Arg Glu Glu Ile Ala His Asn Met Gln Ser Thr Leu Asp Asp
                 170                 175                 180

 Ala Thr Asp Ala Trp Gly Ile Lys Val Glu Arg Val Glu Ile Lys
                 185                 190                 195

 Asp Val Lys Leu Pro Val Gln Leu Gln Arg Ala Met Ala Ala Glu
                 200                 205                 210

 Ala Glu Ala Ser Arg Glu Ala Arg Ala Lys Val Ile Ala Ala Glu
                 215                 220                 225

 Gly Glu Met Asn Ala Ser Arg Ala Leu Lys Glu Ala Ser Met Val
                 230                 235                 240

 Ile Thr Glu Ser Pro Ala Ala Leu Gln Leu Arg Tyr Leu Gln Thr
                 245                 250                 255

 Leu Thr Thr Ile Ala Ala Glu Lys Asn Ser Thr Ile Val Phe Pro
                 260                 265                 270

 Leu Pro Ile Asp Met Leu Gln Gly Ile Ile Gly Ala Lys His Ser
                 275                 280                 285

 His Leu Gly


<210> 195
<211> 3065
<212> DNA
<213> Homo sapien

<400> 195
 gcagcctgag gaaaaaaaga gaaaaagata aaaaaaatct gaaaacgctt 50

 caaaatcctg aaaaaaaaaa ggaaaagaaa aaacgaatcc tcggagaacc 100

 cgcggggaag tcactttcgt acgcttccgg cctgccccgc gcccgccgcc 150

 gcagcgcttg gcgtccgtcg gtctccgtcc gtcggtccgg gggtgagccg 200

 cccgcccggc ccgccgtgcc ctccccccgc tcgggccccg agccccgcgc 250

 cccggcctgc cccggcgcac cacgtgtccg tgctgccctt cgccgcccgc 300

 ccggggtcgc cgagtcggcg cccacaaaga tttggtttcc ctctgcccgg 350

 cggttgtaat cttaaaccgc cggagcccga ggcctatatt tatagagaaa 400

 cgcgtgtccc cgaggcccgc cgtgggcagc gtccggtcgc ctcttaaagg 450

 atttttaccc ttcggaaggg gattccccgt ttaatttttt tcctactttg 500

 attttttgaa atttggagcc ttcgcaccag gaccgcggag aagtgcaaag 550

 tcgcggggag ggccgtattg tgcggagagc cttttgtctg cggtgctgcg 600

 gccgtgggag ccggcccccg cctcccgttt ccgtcccgtc tccaagcccg 650

 ccgactccag ctcgtcctcg ccgcgccggt gccacctgtg agccggcgcg 700

 ggcccgggct ccggctccga aggcgcccct ttgtcctgcg gcgggcccga 750

 taagaagtcc tctggcgggg ctcggggtgg tggggggcgg ggagatgaac 800

 gctgcggcca gcagctaccc catggcctcc ctgtacgtgg gcgacctgca 850

 ttcggacgtc accgaggcca tgctgtacga aaagttcagc cccgcggggc 900

 ctgtgctgtc catccgggtc tgccgcgata tgatcacccg ccgctccctg 950

 ggctatgcct acgtcaactt ccagcagccg gccgacgctg agcgggcttt 1000

 ggacaccatg aactttgatg tgattaaggg aaagccaatc cgcatcatgt 1050

 ggtctcagag ggatccctct ttgagaaaat ctggtgtggg aaacgtcttc 1100

 atcaagaacc tggacaaatc tatagataac aaggcacttt atgatacttt 1150

 ttctgctttt ggaaacatac tgtcctgcaa ggtggtgtgt gatgagaacg 1200

 gctctaaggg ttatgccttt gtccacttcg agacccaaga ggctgccgac 1250

 aaggccatcg agaagatgaa tggcatgctc ctcaatgacc gcaaagtatt 1300

 tgtgggcaga ttcaagtctc gcaaagagcg ggaagctgag cttggagcca 1350

 aagccaagga attcaccaat gtttatatca aaaactttgg ggaagaggtg 1400

 gatgatgaga gtctgaaaga gctattcagt cagtttggta agaccctaag 1450

 tgtcaaggtg atgagagatc ccaatgggaa atccaaaggc tttggctttg 1500

 tgagttacga aaaacacgag gatgccaata aggctgtgga agagatgaat 1550

 ggaaaagaaa taagtggtaa aatcatattt gtaggccgtg cacaaaagaa 1600

 agtagaacgg caggcagagt taaaacggaa atttgaacag ttgaaacagg 1650

 agagaattag tcgatatcag ggggtgaatc tctacattaa gaacttggat 1700

 gacactattg atgatgagaa attaaggaaa gaattttctc cttttggatc 1750

 aattaccagt gctaaggtaa tgctggagga tggaagaagc aaagggtttg 1800

 gcttcgtctg cttctcatct cctgaagaag caaccaaagc agtcactgag 1850

 atgaatggac gcattgtggg ctccaagcca ctatatgttg ccctggccca 1900

 gaggaaggaa gagagaaagg ctcacctgac caaccagtat atgcaacgag 1950

 tggctggaat gagagcactt cctgccaatg ccatcttaaa tcagttccag 2000

 cctgcagcgg gtggctactt tgtgccagca gtcccacagg ctcagggaag 2050

 gcctccatat tatacaccta accagttagc acagatgagg cctaatccac 2100

 gctggcagca aggtgggaga cctcaaggct tccaaggaat gccaagtgct 2150

 atacgccagt ctgggcctcg tccaactctt cgccatctgg ctccaactgg 2200

 gtctgagtgc ccggaccgct tggctatgga ctttggtggg gctggtgccg 2250

 cccagcaagg gctgactgac agctgccagt ctggaggcgt tcccacagct 2300

 gtgcagaact tagcgccacg cgctgctgtt gctgctgctg ctccccgggc 2350

 tgttgccccc tacaaatacg cctccagtgt ccgcagccct catcctgcca 2400

 tacagcctct gcaggcaccc cagcctgcgg tccatgtgca ggggcaggag 2450

 ccactgactg cctccatgct ggctgcagca cccccccagg aacagaagca 2500

 gatgctggga gaacgcttgt tcccactcat ccaaacaatg cattcaaatc 2550

 tggctgggaa gatcacggga atgctgctgg agatagacaa ctctgagctg 2600

 ctgcacatgt tagagtcccc cgagtctctc cgctccaagg tggatgaagc 2650

 tgtagcagtt ctacaggctc atcatgccaa gaaagaagct gcccagaagg 2700

 tgggcgctgt tgctgctgct acctcttaga caaggaaaaa ccgattcaaa 2750

 agccaaataa ccccttatgg aattcaactc aaggtttgaa gacttcctag 2800

 cttgtcctat ggacctcaac accaaggatt acaaattgca aatttaatag 2850

 gtcattttgt atcaaaaggt caattatgaa gcacctagaa tttttcaatt 2900

 atacgaatat gttctttggg ttctgctgtg gcccagacag tgttaacttt 2950

 ttttttattg tgggttttga ttttttcccc cagaaattgg ttttatttga 3000

 tgtacccaag tcttacgttt cccaataaag aaaaaaaatc tccataaaaa 3050

 aagtcgagcg gccgc 3065

<210> 196
<211> 644
<212> PRT
<213> Homo sapien

<400> 196
 Met Asn Ala Ala Ala Ser Ser Tyr Pro Met Ala Ser Leu Tyr Val
   1               5                  10                  15

 Gly Asp Leu His Ser Asp Val Thr Glu Ala Met Leu Tyr Glu Lys
                  20                  25                  30

 Phe Ser Pro Ala Gly Pro Val Leu Ser Ile Arg Val Cys Arg Asp
                  35                  40                  45

 Met Ile Thr Arg Arg Ser Leu Gly Tyr Ala Tyr Val Asn Phe Gln
                  50                  55                  60

 Gln Pro Ala Asp Ala Glu Arg Ala Leu Asp Thr Met Asn Phe Asp
                  65                  70                  75

 Val Ile Lys Gly Lys Pro Ile Arg Ile Met Trp Ser Gln Arg Asp
                  80                  85                  90

 Pro Ser Leu Arg Lys Ser Gly Val Gly Asn Val Phe Ile Lys Asn
                  95                 100                 105

 Leu Asp Lys Ser Ile Asp Asn Lys Ala Leu Tyr Asp Thr Phe Ser
                 110                 115                 120

 Ala Phe Gly Asn Ile Leu Ser Cys Lys Val Val Cys Asp Glu Asn
                 125                 130                 135

 Gly Ser Lys Gly Tyr Ala Phe Val His Phe Glu Thr Gln Glu Ala
                 140                 145                 150

 Ala Asp Lys Ala Ile Glu Lys Met Asn Gly Met Leu Leu Asn Asp
                 155                 160                 165

 Arg Lys Val Phe Val Gly Arg Phe Lys Ser Arg Lys Glu Arg Glu
                 170                 175                 180

 Ala Glu Leu Gly Ala Lys Ala Lys Glu Phe Thr Asn Val Tyr Ile
                 185                 190                 195

 Lys Asn Phe Gly Glu Glu Val Asp Asp Glu Ser Leu Lys Glu Leu
                 200                 205                 210

 Phe Ser Gln Phe Gly Lys Thr Leu Ser Val Lys Val Met Arg Asp
                 215                 220                 225

 Pro Asn Gly Lys Ser Lys Gly Phe Gly Phe Val Ser Tyr Glu Lys
                 230                 235                 240

 His Glu Asp Ala Asn Lys Ala Val Glu Glu Met Asn Gly Lys Glu
                 245                 250                 255

 Ile Ser Gly Lys Ile Ile Phe Val Gly Arg Ala Gln Lys Lys Val
                 260                 265                 270

 Glu Arg Gln Ala Glu Leu Lys Arg Lys Phe Glu Gln Leu Lys Gln
                 275                 280                 285

 Glu Arg Ile Ser Arg Tyr Gln Gly Val Asn Leu Tyr Ile Lys Asn
                 290                 295                 300

 Leu Asp Asp Thr Ile Asp Asp Glu Lys Leu Arg Lys Glu Phe Ser
                 305                 310                 315

 Pro Phe Gly Ser Ile Thr Ser Ala Lys Val Met Leu Glu Asp Gly
                 320                 325                 330

 Arg Ser Lys Gly Phe Gly Phe Val Cys Phe Ser Ser Pro Glu Glu
                 335                 340                 345

 Ala Thr Lys Ala Val Thr Glu Met Asn Gly Arg Ile Val Gly Ser
                 350                 355                 360

 Lys Pro Leu Tyr Val Ala Leu Ala Gln Arg Lys Glu Glu Arg Lys
                 365                 370                 375

 Ala His Leu Thr Asn Gln Tyr Met Gln Arg Val Ala Gly Met Arg
                 380                 385                 390

 Ala Leu Pro Ala Asn Ala Ile Leu Asn Gln Phe Gln Pro Ala Ala
                 395                 400                 405

 Gly Gly Tyr Phe Val Pro Ala Val Pro Gln Ala Gln Gly Arg Pro
                 410                 415                 420

 Pro Tyr Tyr Thr Pro Asn Gln Leu Ala Gln Met Arg Pro Asn Pro
                 425                 430                 435

 Arg Trp Gln Gln Gly Gly Arg Pro Gln Gly Phe Gln Gly Met Pro
                 440                 445                 450

 Ser Ala Ile Arg Gln Ser Gly Pro Arg Pro Thr Leu Arg His Leu
                 455                 460                 465

 Ala Pro Thr Gly Ser Glu Cys Pro Asp Arg Leu Ala Met Asp Phe
                 470                 475                 480

 Gly Gly Ala Gly Ala Ala Gln Gln Gly Leu Thr Asp Ser Cys Gln
                 485                 490                 495

 Ser Gly Gly Val Pro Thr Ala Val Gln Asn Leu Ala Pro Arg Ala
                 500                 505                 510

 Ala Val Ala Ala Ala Ala Pro Arg Ala Val Ala Pro Tyr Lys Tyr
                 515                 520                 525

 Ala Ser Ser Val Arg Ser Pro His Pro Ala Ile Gln Pro Leu Gln
                 530                 535                 540

 Ala Pro Gln Pro Ala Val His Val Gln Gly Gln Glu Pro Leu Thr
                 545                 550                 555

 Ala Ser Met Leu Ala Ala Ala Pro Pro Gln Glu Gln Lys Gln Met
                 560                 565                 570

 Leu Gly Glu Arg Leu Phe Pro Leu Ile Gln Thr Met His Ser Asn
                 575                 580                 585

 Leu Ala Gly Lys Ile Thr Gly Met Leu Leu Glu Ile Asp Asn Ser
                 590                 595                 600

 Glu Leu Leu His Met Leu Glu Ser Pro Glu Ser Leu Arg Ser Lys
                 605                 610                 615

 Val Asp Glu Ala Val Ala Val Leu Gln Ala His His Ala Lys Lys
                 620                 625                 630

 Glu Ala Ala Gln Lys Val Gly Ala Val Ala Ala Ala Thr Ser
                 635                 640

<210> 197
<211> 1273
<212> DNA
<213> Homo sapien

<400> 197
 caagatggcg gcagctgcgg cttcgcttcg cggggtagtg ttgggcccgc 50

 ggggcgcggg gctcccgggc gcgcgtgccc ggggtctgct gtgcagcgcg 100

 cggcccgggc agctcccgct acggacacct caggcagtgg ccttgtcgtc 150

 gaagtctggc ctttcccgag gccggaaagt gatgctgtca gcgctgggca 200

 tgctggcggc agggggtgcg gggctggccg tggctctgca ttcggctgtg 250

 agtgccagtg acctggagct gcaccccccc agctatccgt ggtctcaccg 300

 tggcctcctc tcttccttgg accacaccag catccggagg ggtttccagg 350

 tatataagca ggtgtgcgcc tcctgccaca gcatggactt cgtggcctac 400

 cgccacctgg tgggcgtgtg ctacacggag gatgaagcta aggagctggc 450

 tgcggaggtg gaggttcaag acggccccaa tgaagatggg gagatgttca 500

 tgcggccagg gaagctgttc gactatttcc caaaaccata ccccaacagt 550

 gaggctgctc gagctgccaa caacggagca ttgccccctg acctcagcta 600

 catcgtgcga gctaggcatg gtggtgagga ctacgtcttc tccctgctca 650

 cgggctactg cgagccaccc accggggtgt cactgcggga aggtctctac 700

 ttcaacccct actttcctgg ccaggccatt gccatggccc ctcccatcta 750

 cacagatgtc ttagagtttg acgatggcac cccagctacc atgtcccaga 800

 tagccaagga tgtgtgcacc ttcctgcgct gggcatctga gccagagcac 850

 gaccatcgaa aacgcatggg gctcaagatg ttgatgatga tggctctgct 900

 ggtgcccctg gtctacacca taaagcggca caagtggtca gtcctgaaga 950

 gtcggaagct ggcatatcgg ccgcccaagt gaccctgtcc agtgtctgct 1000

 tgccatcctg ccagaacagg ccctcaagcc caagagccat cccaggcctg 1050

 ttcaggcctc agctaagcct ctcttcatct ggaagaagag gcaagggggc 1100

 aggagaccag gctctagctc tgggccctcc ttcagccccc atcatgggaa 1150

 taaattaatt ttctcaatgt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1250

 aaaaaaaaaa aaaaaaaaaa aaa 1273

<210> 198
<211> 325
<212> PRT
<213> Homo sapien

<400> 198
 Met Ala Ala Ala Ala Ala Ser Leu Arg Gly Val Val Leu Gly Pro
   1               5                  10                  15

 Arg Gly Ala Gly Leu Pro Gly Ala Arg Ala Arg Gly Leu Leu Cys
                  20                  25                  30

 Ser Ala Arg Pro Gly Gln Leu Pro Leu Arg Thr Pro Gln Ala Val
                  35                  40                  45

 Ala Leu Ser Ser Lys Ser Gly Leu Ser Arg Gly Arg Lys Val Met
                  50                  55                  60

 Leu Ser Ala Leu Gly Met Leu Ala Ala Gly Gly Ala Gly Leu Ala
                  65                  70                  75

 Val Ala Leu His Ser Ala Val Ser Ala Ser Asp Leu Glu Leu His
                  80                  85                  90

 Pro Pro Ser Tyr Pro Trp Ser His Arg Gly Leu Leu Ser Ser Leu
                  95                 100                 105

 Asp His Thr Ser Ile Arg Arg Gly Phe Gln Val Tyr Lys Gln Val
                 110                 115                 120

 Cys Ala Ser Cys His Ser Met Asp Phe Val Ala Tyr Arg His Leu
                 125                 130                 135

 Val Gly Val Cys Tyr Thr Glu Asp Glu Ala Lys Glu Leu Ala Ala
                 140                 145                 150

 Glu Val Glu Val Gln Asp Gly Pro Asn Glu Asp Gly Glu Met Phe
                 155                 160                 165

 Met Arg Pro Gly Lys Leu Phe Asp Tyr Phe Pro Lys Pro Tyr Pro
                 170                 175                 180

 Asn Ser Glu Ala Ala Arg Ala Ala Asn Asn Gly Ala Leu Pro Pro
                 185                 190                 195

 Asp Leu Ser Tyr Ile Val Arg Ala Arg His Gly Gly Glu Asp Tyr
                 200                 205                 210

 Val Phe Ser Leu Leu Thr Gly Tyr Cys Glu Pro Pro Thr Gly Val
                 215                 220                 225

 Ser Leu Arg Glu Gly Leu Tyr Phe Asn Pro Tyr Phe Pro Gly Gln
                 230                 235                 240

 Ala Ile Ala Met Ala Pro Pro Ile Tyr Thr Asp Val Leu Glu Phe
                 245                 250                 255

 Asp Asp Gly Thr Pro Ala Thr Met Ser Gln Ile Ala Lys Asp Val
                 260                 265                 270

 Cys Thr Phe Leu Arg Trp Ala Ser Glu Pro Glu His Asp His Arg
                 275                 280                 285

 Lys Arg Met Gly Leu Lys Met Leu Met Met Met Ala Leu Leu Val
                 290                 295                 300

 Pro Leu Val Tyr Thr Ile Lys Arg His Lys Trp Ser Val Leu Lys
                 305                 310                 315

 Ser Arg Lys Leu Ala Tyr Arg Pro Pro Lys
                 320                 325

<210> 199
<211> 2391
<212> DNA
<213> Homo sapien

<400> 199
 cgcaaccgga actagccttc tgggggccgg cttggtttat ctctggcggc 50

 cttgtagtcg tctccgagac tccccacccc tccttccctc ttgaccccct 100

 aggtttgatt gccctttccc cgaaacaact atcatgagcg cgaggctgcc 150

 ggtgttgtct ccacctcggt ggccgcggct gttgctgctg tcgctgctcc 200

 tgctgggggc ggttcctggc ccgcgccgga gcggcgcttt ctacctgccc 250

 ggcctggcgc ccgtcaactt ctgcgacgaa gaaaaaaaga gcgacgagtg 300

 caaggccgaa atagaactat ttgtgaacag acttgattca gtggaatcag 350

 ttcttcctta tgaatacaca gcgtttgatt tttgccaagc atcagaagga 400

 aagcgcccat ctgaaaatct tggtcaggta ctattcgggg aaagaattga 450

 accttcacca tataagttta cgtttaataa gaaggagacc tgtaagcttg 500

 tttgtacaaa aacataccat acagagaaag ctgaagacaa acaaaagtta 550

 gaattcttga aaaaaagcat gttattgaat tatcaacatc actggattgt 600

 ggataatatg cctgtaacgt ggtgttacga tgttgaagat ggtcagaggt 650

 tctgtaatcc tggatttcct attggctgtt acattacaga taaaggccat 700

 gcaaaagatg cctgtgttat tagttcagat ttccatgaaa gagatacatt 750

 ttacatcttc aaccatgttg acatcaaaat atactatcat gttgttgaaa 800

 ctgggtccat gggagcaaga ttagtggctg ctaaacttga accgaaaagc 850

 ttcaaacata cccatataga taaaccagac tgctcagggc cccccatgga 900

 cataagtaac aaggcttctg gggagataaa aattgcctat acttactctg 950

 ttagcttcga ggaagatgat aagatcagat gggcgtctag atgggactat 1000

 attctggagt ctatgcctca tacccacatt cagtggttta gcattatgaa 1050

 ttccctggtc attgttctct tcttatctgg aatggtagct atgattatgt 1100

 tacggacact gcacaaagat attgctagat ataatcagat ggactctacg 1150

 gaagatgccc aggaagaatt tggctggaaa cttgttcatg gtgatatatt 1200

 ccgtcctcca agaaaaggga tgctgctatc agtctttcta ggatccggga 1250

 cacagatttt aattatgacc tttgtgactc tatttttcgc ttgcctggga 1300

 tttttgtcac ctgccaaccg aggagcgctg atgacgtgtg ctgtggtcct 1350

 gtgggtgctg ctgggcaccc ctgcaggcta tgttgctgcc agattctata 1400

 agtcctttgg aggtgagaag tggaaaacaa atgttttatt aacatcattt 1450

 ctttgtcctg ggattgtatt tgctgacttc tttataatga atctgatcct 1500

 ctggggagaa ggatcttcag cagctattcc ttttgggaca ctggttgcca 1550

 tattggccct ttggttctgc atatctgtgc ctctgacgtt tattggtgca 1600

 tactttggtt ttaagaagaa tgccattgaa cacccagttc gaaccaatca 1650

 gattccacgt cagattcctg aacagtcgtt ctacacgaag cccttgcctg 1700

 gtattatcat gggagggatt ttgccctttg gctgcatctt tatacaactt 1750

 ttcttcattc tgaatagtat ttggtcacac cagatgtatt acatgtttgg 1800

 cttcctattt ctggtgttta tcattttggt tattacctgt tctgaagcaa 1850

 ctatacttct ttgctatttc cacctatgtg cagaggatta tcattggcaa 1900

 tggcgttcat tccttacgag tggctttact gcagtttatt tcttaatcta 1950

 tgcagtacac tacttctttt caaaactgca gatcacggga acagcaagca 2000

 caattctgta ctttggttat accatgataa tggttttgat cttctttctt 2050

 tttacaggaa caattggctt ctttgcatgc ttttggtttg ttaccaaaat 2100

 atacagtgtg gtgaaggttg actgaagaag tccagtgtgt ccagttaaaa 2150

 cagaaataaa ttaaactctt catcaacaaa gacctgtttt tgtgactgcc 2200

 ttgagtttta tcagaattat tggcctagta atccttcaga aacaccgtaa 2250

 ttctaaataa acctcttccc atacaccttt cccccataag atctgtcttc 2300

 aacactataa agcatttgta ttgtgatttg attaagtata tatttggttg 2350

 ttctcaatga agagcaaatt taaatattat gtgcatttga a 2391

<210> 200
<211> 663
<212> PRT
<213> Homo sapien

<400> 200
 Met Ser Ala Arg Leu Pro Val Leu Ser Pro Pro Arg Trp Pro Arg
   1               5                  10                  15

 Leu Leu Leu Leu Ser Leu Leu Leu Leu Gly Ala Val Pro Gly Pro
                  20                  25                  30

 Arg Arg Ser Gly Ala Phe Tyr Leu Pro Gly Leu Ala Pro Val Asn
                  35                  40                  45

 Phe Cys Asp Glu Glu Lys Lys Ser Asp Glu Cys Lys Ala Glu Ile
                  50                  55                  60

 Glu Leu Phe Val Asn Arg Leu Asp Ser Val Glu Ser Val Leu Pro
                  65                  70                  75

 Tyr Glu Tyr Thr Ala Phe Asp Phe Cys Gln Ala Ser Glu Gly Lys
                  80                  85                  90

 Arg Pro Ser Glu Asn Leu Gly Gln Val Leu Phe Gly Glu Arg Ile
                  95                 100                 105

 Glu Pro Ser Pro Tyr Lys Phe Thr Phe Asn Lys Lys Glu Thr Cys
                 110                 115                 120

 Lys Leu Val Cys Thr Lys Thr Tyr His Thr Glu Lys Ala Glu Asp
                 125                 130                 135

 Lys Gln Lys Leu Glu Phe Leu Lys Lys Ser Met Leu Leu Asn Tyr
                 140                 145                 150

 Gln His His Trp Ile Val Asp Asn Met Pro Val Thr Trp Cys Tyr
                 155                 160                 165

 Asp Val Glu Asp Gly Gln Arg Phe Cys Asn Pro Gly Phe Pro Ile
                 170                 175                 180

 Gly Cys Tyr Ile Thr Asp Lys Gly His Ala Lys Asp Ala Cys Val
                 185                 190                 195

 Ile Ser Ser Asp Phe His Glu Arg Asp Thr Phe Tyr Ile Phe Asn
                 200                 205                 210

 His Val Asp Ile Lys Ile Tyr Tyr His Val Val Glu Thr Gly Ser
                 215                 220                 225

 Met Gly Ala Arg Leu Val Ala Ala Lys Leu Glu Pro Lys Ser Phe
                 230                 235                 240

 Lys His Thr His Ile Asp Lys Pro Asp Cys Ser Gly Pro Pro Met
                 245                 250                 255

 Asp Ile Ser Asn Lys Ala Ser Gly Glu Ile Lys Ile Ala Tyr Thr
                 260                 265                 270

 Tyr Ser Val Ser Phe Glu Glu Asp Asp Lys Ile Arg Trp Ala Ser
                 275                 280                 285

 Arg Trp Asp Tyr Ile Leu Glu Ser Met Pro His Thr His Ile Gln
                 290                 295                 300

 Trp Phe Ser Ile Met Asn Ser Leu Val Ile Val Leu Phe Leu Ser
                 305                 310                 315

 Gly Met Val Ala Met Ile Met Leu Arg Thr Leu His Lys Asp Ile
                 320                 325                 330

 Ala Arg Tyr Asn Gln Met Asp Ser Thr Glu Asp Ala Gln Glu Glu
                 335                 340                 345

 Phe Gly Trp Lys Leu Val His Gly Asp Ile Phe Arg Pro Pro Arg
                 350                 355                 360

 Lys Gly Met Leu Leu Ser Val Phe Leu Gly Ser Gly Thr Gln Ile
                 365                 370                 375

 Leu Ile Met Thr Phe Val Thr Leu Phe Phe Ala Cys Leu Gly Phe
                 380                 385                 390

 Leu Ser Pro Ala Asn Arg Gly Ala Leu Met Thr Cys Ala Val Val
                 395                 400                 405

 Leu Trp Val Leu Leu Gly Thr Pro Ala Gly Tyr Val Ala Ala Arg
                 410                 415                 420

 Phe Tyr Lys Ser Phe Gly Gly Glu Lys Trp Lys Thr Asn Val Leu
                 425                 430                 435

 Leu Thr Ser Phe Leu Cys Pro Gly Ile Val Phe Ala Asp Phe Phe
                 440                 445                 450

 Ile Met Asn Leu Ile Leu Trp Gly Glu Gly Ser Ser Ala Ala Ile
                 455                 460                 465

 Pro Phe Gly Thr Leu Val Ala Ile Leu Ala Leu Trp Phe Cys Ile
                 470                 475                 480

 Ser Val Pro Leu Thr Phe Ile Gly Ala Tyr Phe Gly Phe Lys Lys
                 485                 490                 495

 Asn Ala Ile Glu His Pro Val Arg Thr Asn Gln Ile Pro Arg Gln
                 500                 505                 510

 Ile Pro Glu Gln Ser Phe Tyr Thr Lys Pro Leu Pro Gly Ile Ile
                 515                 520                 525

 Met Gly Gly Ile Leu Pro Phe Gly Cys Ile Phe Ile Gln Leu Phe
                 530                 535                 540

 Phe Ile Leu Asn Ser Ile Trp Ser His Gln Met Tyr Tyr Met Phe
                 545                 550                 555

 Gly Phe Leu Phe Leu Val Phe Ile Ile Leu Val Ile Thr Cys Ser
                 560                 565                 570

 Glu Ala Thr Ile Leu Leu Cys Tyr Phe His Leu Cys Ala Glu Asp
                 575                 580                 585

 Tyr His Trp Gln Trp Arg Ser Phe Leu Thr Ser Gly Phe Thr Ala
                 590                 595                 600

 Val Tyr Phe Leu Ile Tyr Ala Val His Tyr Phe Phe Ser Lys Leu
                 605                 610                 615

 Gln Ile Thr Gly Thr Ala Ser Thr Ile Leu Tyr Phe Gly Tyr Thr
                 620                 625                 630

 Met Ile Met Val Leu Ile Phe Phe Leu Phe Thr Gly Thr Ile Gly
                 635                 640                 645

 Phe Phe Ala Cys Phe Trp Phe Val Thr Lys Ile Tyr Ser Val Val
                 650                 655                 660

 Lys Val Asp


<210> 201
<211> 3595
<212> DNA
<213> Homo sapien

<400> 201
 aaaagttgcg gggcatagac gagcgccccg ggacgcagct agcgcgaccc 50

 tgagccggcg cccgtggtcc ggccatggac gacctcgacg ccctgctggc 100

 ggacttggag tctaccacct cccacatctc caaacggcct gtgttcttgt 150

 cggaggagac cccctactca tacccaactg gaaaccacac ataccaggag 200

 attgccgtgc caccccccgt ccccccaccc ccgtccagcg aggccctcaa 250

 tggcacaatc cttgacccct tagaccagtg gcagcccagc ggctcccgat 300

 tcatccacca gcagcctcag tcctcatcac ctgtgtacgg ctccagtgcc 350

 aaaacttcca gtgtctccaa ccctcaggac agtgttggct ctccgtgctc 400

 ccgagtgggt gaggaggagc acgtctacag cttccccaac aagcagaaat 450

 cagctgagcc ttcacccacc gtaatgagca cgtccctggg cagcaacctt 500

 tctgaactcg accgcctgct gctggaactg aacgctgtac agcataaccc 550

 gccaggcttc cctgcagatg aggccaactc aagccccccg cttcctgggg 600

 ccctgagccc cctctatggt gtcccagaga ctaacagccc cttgggaggc 650

 aaagctgggc ccctgacgaa agagaagcct aagcggaatg ggggccgggg 700

 cctggaggac gtgcggccca gtgtggagag tctcttggat gaactggaga 750

 gctccgtgcc cagccccgtc cctgccatca ctgtgaacca gggcgagatg 800

 agcagcccgc agcgcgtcac ctccacccaa cagcagacac gcatctcggc 850

 ctcctctgcc accagggagc tggacgagct gatggcttcg ctgtcggatt 900

 tcaagttcat ggcccagggg aagacaggga gcagctcacc ccctgggggg 950

 cccccgaagc ccgggagcca gctggacagc atgctgggga gcctgcagtc 1000

 tgacctgaac aagctggggg tcgccacagt cgccaaagga gtctgcgggg 1050

 cctgcaagaa gcccatcgcc gggcaggttg tgaccgccat ggggaagacg 1100

 tggcaccccg agcacttcgt ctgcacccac tgccaggagg agatcggatc 1150

 ccggaacttc ttcgagcggg atggacagcc ctactgtgaa aaggactacc 1200

 acaacctctt ctccccgcgc tgctactact gcaacggccc catcctggat 1250

 aaagtggtga cagcccttga ccggacgtgg caccctgaac acttcttctg 1300

 tgcacagtgt ggagccttct ttggtcccga agggttccac gagaaggacg 1350

 gcaaggccta ctgtcgcaag gactacttcg acatgttcgc acccaagtgt 1400

 ggcggctgcg cccgggccat cctggagaac tatatctcag ccctcaacac 1450

 gctgtggcat cctgagtgct ttgtgtgccg ggaatgcttc acgccattcg 1500

 tgaacggcag cttcttcgag cacgacgggc agccctactg tgaggtgcac 1550

 taccacgagc ggcgcggctc gctgtgttct ggctgccaga agcccatcac 1600

 cggccgctgc atcaccgcca tggccaagaa gttccacccc gagcacttcg 1650

 tctgtgcctt ctgcctcaag cagctcaaca agggcacctt caaggagcag 1700

 aacgacaagc cttactgtca gaactgcttc ctcaagctct tctgctaggt 1750

 gccctgcccc tgtctctgcc ccccttcccc agccagcatc cccaactgcg 1800

 actgtgacct agagacttca cccgggggtg aaggggtaaa cccgactgaa 1850

 actggaaccc ttgtcctccg ctggtgcggg atggacagag ggccgtgagg 1900

 ggtccccctg cttgtcttca cccctgccag agcctctggg ccccctcctc 1950

 cctcctgtag ctctccctag gctgcccact ctccatcctc cccaggggta 2000

 gaggctgggg gctccacccc agcccatgta cgtccccacg aactggcctg 2050

 gccagcaccc cacactggag ccatctcttc ctcatatttc agcagtgcag 2100

 ccggggggca gggaagggca ggcagggtct gttggggtct ctttttatcc 2150

 ttattcctcc cccgacctaa ttgtctttgt tctgtgatta ttgggggaca 2200

 cccggctccc tccagacaat gccagcataa atccatccat ccaaaggcag 2250

 agaaccaaag gggccatgga aggttctctg tgctcctcct acccttccag 2300

 tgccctaggc ctggcgactg cccctgcctt ttagacccgc actccccttt 2350

 tatacctgct cttgttctac tgagaaaagc ctctccagca ataatgtttt 2400

 ctagtcactt cctccgtctc cgggacggcg tgcctggaca ctgtccgact 2450

 ttgatagatt tctacactga ggttgaattc atatcgcctg agatgtttta 2500

 cttctctata caccatgatt ttgtagagat attaaagacg ttcccttttg 2550

 tatctcttct tcatcaccgc cactgggcct tcactgatgg tgtctggtgt 2600

 gtagattgct ttgtctgtgg ggtggggtgg ggaagcaata tgtattttat 2650

 tgtttcttag cacaagcagg tgtgctggga gcagctctgt gactccccct 2700

 ctttcacttc atagctccca ggactgtttt ataaactgct gctatttgga 2750

 aaccccttct ttacttccca ggccagcaag ccttcactga aactggttga 2800

 agagtgttgc acccttttgg gcctagaatt ctgaacttta tctgttctgt 2850

 ttctgtggga ggagaagggg aagtatgttt tggggggctg cttcctgtct 2900

 gagtaagccc tcaggagcct cttgctcccc tgtgaacccc tgaaccttct 2950

 gagcccccct gcttctatgg ggctctctct tctgccttct caggaaagct 3000

 gtgtctgatt ttggccatca ggactctgac gtctctttgg tcttgttgat 3050

 ttacctctgg gcatatccct tccccagatc tgctcctccc ctttcacagg 3100

 tgggatcggc actcaggggg tctggaaaga aggtcataag ggagcatgat 3150

 aggatttggg gcagagggac aggctcctct ggggaaaccc cccagagctc 3200

 tttaccaagg atgaaagagg agccaggcct tgggctcctg atgaccagaa 3250

 aggggccacc ggggtctaat ggtgacagtc caaaccactc cactggcctc 3300

 ctggcagaag ccgagtgtgc tggggtctcc gaagagggtc cctccttttt 3350

 gggggaaggt cagcccagcc cctccaaagg tctgatgtct ccactttcac 3400

 ccgcaggcct taccgctctg tttatagtga cccaccctag atcttcccca 3450

 agagggactg gggtttctgg ggtccattct ctgagtcagt ggttatttga 3500

 aaatttgatt ttgattttat tttttctctg taaacttcca agctggcttt 3550

 tcccatttca attcctgtga tttatgccaa taaagtttgc ccatg 3595

<210> 202
<211> 557
<212> PRT
<213> Homo sapien

<400> 202
 Met Asp Asp Leu Asp Ala Leu Leu Ala Asp Leu Glu Ser Thr Thr
   1               5                  10                  15

 Ser His Ile Ser Lys Arg Pro Val Phe Leu Ser Glu Glu Thr Pro
                  20                  25                  30

 Tyr Ser Tyr Pro Thr Gly Asn His Thr Tyr Gln Glu Ile Ala Val
                  35                  40                  45

 Pro Pro Pro Val Pro Pro Pro Pro Ser Ser Glu Ala Leu Asn Gly
                  50                  55                  60

 Thr Ile Leu Asp Pro Leu Asp Gln Trp Gln Pro Ser Gly Ser Arg
                  65                  70                  75

 Phe Ile His Gln Gln Pro Gln Ser Ser Ser Pro Val Tyr Gly Ser
                  80                  85                  90

 Ser Ala Lys Thr Ser Ser Val Ser Asn Pro Gln Asp Ser Val Gly
                  95                 100                 105

 Ser Pro Cys Ser Arg Val Gly Glu Glu Glu His Val Tyr Ser Phe
                 110                 115                 120

 Pro Asn Lys Gln Lys Ser Ala Glu Pro Ser Pro Thr Val Met Ser
                 125                 130                 135

 Thr Ser Leu Gly Ser Asn Leu Ser Glu Leu Asp Arg Leu Leu Leu
                 140                 145                 150

 Glu Leu Asn Ala Val Gln His Asn Pro Pro Gly Phe Pro Ala Asp
                 155                 160                 165

 Glu Ala Asn Ser Ser Pro Pro Leu Pro Gly Ala Leu Ser Pro Leu
                 170                 175                 180

 Tyr Gly Val Pro Glu Thr Asn Ser Pro Leu Gly Gly Lys Ala Gly
                 185                 190                 195

 Pro Leu Thr Lys Glu Lys Pro Lys Arg Asn Gly Gly Arg Gly Leu
                 200                 205                 210

 Glu Asp Val Arg Pro Ser Val Glu Ser Leu Leu Asp Glu Leu Glu
                 215                 220                 225

 Ser Ser Val Pro Ser Pro Val Pro Ala Ile Thr Val Asn Gln Gly
                 230                 235                 240

 Glu Met Ser Ser Pro Gln Arg Val Thr Ser Thr Gln Gln Gln Thr
                 245                 250                 255

 Arg Ile Ser Ala Ser Ser Ala Thr Arg Glu Leu Asp Glu Leu Met
                 260                 265                 270

 Ala Ser Leu Ser Asp Phe Lys Phe Met Ala Gln Gly Lys Thr Gly
                 275                 280                 285

 Ser Ser Ser Pro Pro Gly Gly Pro Pro Lys Pro Gly Ser Gln Leu
                 290                 295                 300

 Asp Ser Met Leu Gly Ser Leu Gln Ser Asp Leu Asn Lys Leu Gly
                 305                 310                 315

 Val Ala Thr Val Ala Lys Gly Val Cys Gly Ala Cys Lys Lys Pro
                 320                 325                 330

 Ile Ala Gly Gln Val Val Thr Ala Met Gly Lys Thr Trp His Pro
                 335                 340                 345

 Glu His Phe Val Cys Thr His Cys Gln Glu Glu Ile Gly Ser Arg
                 350                 355                 360

 Asn Phe Phe Glu Arg Asp Gly Gln Pro Tyr Cys Glu Lys Asp Tyr
                 365                 370                 375

 His Asn Leu Phe Ser Pro Arg Cys Tyr Tyr Cys Asn Gly Pro Ile
                 380                 385                 390

 Leu Asp Lys Val Val Thr Ala Leu Asp Arg Thr Trp His Pro Glu
                 395                 400                 405

 His Phe Phe Cys Ala Gln Cys Gly Ala Phe Phe Gly Pro Glu Gly
                 410                 415                 420

 Phe His Glu Lys Asp Gly Lys Ala Tyr Cys Arg Lys Asp Tyr Phe
                 425                 430                 435

 Asp Met Phe Ala Pro Lys Cys Gly Gly Cys Ala Arg Ala Ile Leu
                 440                 445                 450

 Glu Asn Tyr Ile Ser Ala Leu Asn Thr Leu Trp His Pro Glu Cys
                 455                 460                 465

 Phe Val Cys Arg Glu Cys Phe Thr Pro Phe Val Asn Gly Ser Phe
                 470                 475                 480

 Phe Glu His Asp Gly Gln Pro Tyr Cys Glu Val His Tyr His Glu
                 485                 490                 495

 Arg Arg Gly Ser Leu Cys Ser Gly Cys Gln Lys Pro Ile Thr Gly
                 500                 505                 510

 Arg Cys Ile Thr Ala Met Ala Lys Lys Phe His Pro Glu His Phe
                 515                 520                 525

 Val Cys Ala Phe Cys Leu Lys Gln Leu Asn Lys Gly Thr Phe Lys
                 530                 535                 540

 Glu Gln Asn Asp Lys Pro Tyr Cys Gln Asn Cys Phe Leu Lys Leu
                 545                 550                 555

 Phe Cys


<210> 203
<211> 1976
<212> DNA
<213> Homo sapien

<400> 203
 gccacacggt ctttgagctg agtcgaggtg gaccctttga acgcagtcgc 50

 cctacagccg ctgattcccc ccgcatcgcc tcccgtggaa gcccaggccc 100

 gcttcgcagc tttctccctt tgtctcataa ccatgtccac caacgagaat 150

 gctaatacac cagctgcccg tcttcacaga ttcaagaaca agggaaaaga 200

 cagtacagaa atgaggcgtc gcagaataga ggtcaatgtg gagctgagga 250

 aagctaagaa ggatgaccag atgctgaaga ggagaaatgt aagctcattt 300

 cctgatgatg ctacttctcc gctgcaggaa aaccgcaaca accagggcac 350

 tgtaaattgg tctgttgatg acattgtcaa aggcataaat agcagcaatg 400

 tggaaaatca gctccaagct actcaagctg ccaggaaact actttccaga 450

 gaaaaacagc cccccataga caacataatc cgggctggtt tgattccgaa 500

 atttgtgtcc ttcttgggca gaactgattg tagtcccatt cagtttgaat 550

 ctgcttgggc actcactaac attgcttctg ggacatcaga acaaaccaag 600

 gctgtggtag atggaggtgc catcccagca ttcatttctc tgttggcatc 650

 tccccatgct cacatcagtg aacaagctgt ctgggctcta ggaaacattg 700

 caggtgatgg ctcagtgttc cgagacttgg ttattaagta cggtgcagtt 750

 gacccactgt tggctctcct tgcagttcct gatatgtcat ctttagcatg 800

 tggctactta cgtaatctta cctggacact ttctaatctt tgccgcaaca 850

 agaatcctgc acccccgata gatgctgttg agcagattct tcctacctta 900

 gttcggctcc tgcatcatga tgatccagaa gtgttagcag atacctgctg 950

 ggctatttcc taccttactg atggtccaaa tgaacgaatt ggcatggtgg 1000

 tgaaaacagg agttgtgccc caacttgtga agcttctagg agcttctgaa 1050

 ttgccaattg tgactcctgc cctaagagcc atagggaata ttgtcactgg 1100

 tacagatgaa cagactcagg ttgtgattga tgcaggagca ctcgccgtct 1150

 ttcccagcct gctcaccaac cccaaaacta acattcagaa ggaagctacg 1200

 tggacaatgt caaacatcac agccggccgc caggaccaga tacagcaagt 1250

 tgtgaatcat ggattagtcc cattccttgt cagtgttctc tctaaggcag 1300

 attttaagac acaaaaggaa gctgtgtggg ccgtgaccaa ctataccagt 1350

 ggtggaacag ttgaacagat tgtgtacctt gttcactgtg gcataataga 1400

 accgttgatg aacctcttaa ctgcaaaaga taccaagatt attctggtta 1450

 tcctggatgc catttcaaat atctttcagg ctgctgagaa actaggtgaa 1500

 actgagaaac ttagtataat gattgaagaa tgtggaggct tagacaaaat 1550

 tgaagctcta caaaaccatg aaaatgagtc tgtgtataag gcttcgttaa 1600

 gcttaattga gaagtatttc tctgtagagg aagaggaaga tcaaaacgtt 1650

 gtaccagaaa ctacctctga aggctacact ttccaagttc aggatggggc 1700

 tcctgggacc tttaactttt agatcatgta gctgagacat aaatttgttg 1750

 tgtactacgt ttggtatttt gtcttattgt ttctctacta agaactcttt 1800

 cttaaatgtg gtttgttact gtagcacttt ttacactgaa actatacttg 1850

 aacagttcca actgtacata catactgtat gaagcttgtc ctctgactag 1900

 gtttctaatt tctatgtgga atttcctatc ttgcagcatc ctgtaaataa 1950

 acattcaagt ccacccttaa aaaaaa 1976

<210> 204
<211> 529
<212> PRT
<213> Homo sapien

<400> 204
 Met Ser Thr Asn Glu Asn Ala Asn Thr Pro Ala Ala Arg Leu His
   1               5                  10                  15

 Arg Phe Lys Asn Lys Gly Lys Asp Ser Thr Glu Met Arg Arg Arg
                  20                  25                  30

 Arg Ile Glu Val Asn Val Glu Leu Arg Lys Ala Lys Lys Asp Asp
                  35                  40                  45

 Gln Met Leu Lys Arg Arg Asn Val Ser Ser Phe Pro Asp Asp Ala
                  50                  55                  60

 Thr Ser Pro Leu Gln Glu Asn Arg Asn Asn Gln Gly Thr Val Asn
                  65                  70                  75

 Trp Ser Val Asp Asp Ile Val Lys Gly Ile Asn Ser Ser Asn Val
                  80                  85                  90

 Glu Asn Gln Leu Gln Ala Thr Gln Ala Ala Arg Lys Leu Leu Ser
                  95                 100                 105

 Arg Glu Lys Gln Pro Pro Ile Asp Asn Ile Ile Arg Ala Gly Leu
                 110                 115                 120

 Ile Pro Lys Phe Val Ser Phe Leu Gly Arg Thr Asp Cys Ser Pro
                 125                 130                 135

 Ile Gln Phe Glu Ser Ala Trp Ala Leu Thr Asn Ile Ala Ser Gly
                 140                 145                 150

 Thr Ser Glu Gln Thr Lys Ala Val Val Asp Gly Gly Ala Ile Pro
                 155                 160                 165

 Ala Phe Ile Ser Leu Leu Ala Ser Pro His Ala His Ile Ser Glu
                 170                 175                 180

 Gln Ala Val Trp Ala Leu Gly Asn Ile Ala Gly Asp Gly Ser Val
                 185                 190                 195

 Phe Arg Asp Leu Val Ile Lys Tyr Gly Ala Val Asp Pro Leu Leu
                 200                 205                 210

 Ala Leu Leu Ala Val Pro Asp Met Ser Ser Leu Ala Cys Gly Tyr
                 215                 220                 225

 Leu Arg Asn Leu Thr Trp Thr Leu Ser Asn Leu Cys Arg Asn Lys
                 230                 235                 240

 Asn Pro Ala Pro Pro Ile Asp Ala Val Glu Gln Ile Leu Pro Thr
                 245                 250                 255

 Leu Val Arg Leu Leu His His Asp Asp Pro Glu Val Leu Ala Asp
                 260                 265                 270

 Thr Cys Trp Ala Ile Ser Tyr Leu Thr Asp Gly Pro Asn Glu Arg
                 275                 280                 285

 Ile Gly Met Val Val Lys Thr Gly Val Val Pro Gln Leu Val Lys
                 290                 295                 300

 Leu Leu Gly Ala Ser Glu Leu Pro Ile Val Thr Pro Ala Leu Arg
                 305                 310                 315

 Ala Ile Gly Asn Ile Val Thr Gly Thr Asp Glu Gln Thr Gln Val
                 320                 325                 330

 Val Ile Asp Ala Gly Ala Leu Ala Val Phe Pro Ser Leu Leu Thr
                 335                 340                 345

 Asn Pro Lys Thr Asn Ile Gln Lys Glu Ala Thr Trp Thr Met Ser
                 350                 355                 360

 Asn Ile Thr Ala Gly Arg Gln Asp Gln Ile Gln Gln Val Val Asn
                 365                 370                 375

 His Gly Leu Val Pro Phe Leu Val Ser Val Leu Ser Lys Ala Asp
                 380                 385                 390

 Phe Lys Thr Gln Lys Glu Ala Val Trp Ala Val Thr Asn Tyr Thr
                 395                 400                 405

 Ser Gly Gly Thr Val Glu Gln Ile Val Tyr Leu Val His Cys Gly
                 410                 415                 420

 Ile Ile Glu Pro Leu Met Asn Leu Leu Thr Ala Lys Asp Thr Lys
                 425                 430                 435

 Ile Ile Leu Val Ile Leu Asp Ala Ile Ser Asn Ile Phe Gln Ala
                 440                 445                 450

 Ala Glu Lys Leu Gly Glu Thr Glu Lys Leu Ser Ile Met Ile Glu
                 455                 460                 465

 Glu Cys Gly Gly Leu Asp Lys Ile Glu Ala Leu Gln Asn His Glu
                 470                 475                 480

 Asn Glu Ser Val Tyr Lys Ala Ser Leu Ser Leu Ile Glu Lys Tyr
                 485                 490                 495

 Phe Ser Val Glu Glu Glu Glu Asp Gln Asn Val Val Pro Glu Thr
                 500                 505                 510

 Thr Ser Glu Gly Tyr Thr Phe Gln Val Gln Asp Gly Ala Pro Gly
                 515                 520                 525

 Thr Phe Asn Phe


<210> 205
<211> 526
<212> DNA
<213> Homo sapien

<400> 205
 atctctctcg ggtggagtcc ttctgacagc tggtgcgcct gcccgggaac 50

 atcctcctgg actcaatcat ggcttgtggt ctggtcgcca gcaacctgaa 100

 tctcaaacct ggagagtgcc ttcgagtgcg aggcgaggtg gctcctgacg 150

 ctaagagctt cgtgctgaac ctgggcaaag acagcaacaa cctgtgcctg 200

 cacttcaacc ctcgcttcaa cgcccacggc gacgccaaca ccatcgtgtg 250

 caacagcaag gacggcgggg cctgggggac cgagcagcgg gaggctgtct 300

 ttcccttcca gcctggaagt gttgcagagg tgtgcatcac cttcgaccag 350

 gccaacctga ccgtcaagct gccagatgga tacgaattca agttccccaa 400

 ccgcctcaac ctggaggcca tcaactacat ggcagctgac ggtgacttca 450

 agatcaaatg tgtggccttt gactgaaatc agccagccca tggcccccaa 500

 taaaggcagc tgcctctgct cccctg 526

<210> 206
<211> 135
<212> PRT
<213> Homo sapien

<400> 206
 Met Ala Cys Gly Leu Val Ala Ser Asn Leu Asn Leu Lys Pro Gly
   1               5                  10                  15

 Glu Cys Leu Arg Val Arg Gly Glu Val Ala Pro Asp Ala Lys Ser
                  20                  25                  30

 Phe Val Leu Asn Leu Gly Lys Asp Ser Asn Asn Leu Cys Leu His
                  35                  40                  45

 Phe Asn Pro Arg Phe Asn Ala His Gly Asp Ala Asn Thr Ile Val
                  50                  55                  60

 Cys Asn Ser Lys Asp Gly Gly Ala Trp Gly Thr Glu Gln Arg Glu
                  65                  70                  75

 Ala Val Phe Pro Phe Gln Pro Gly Ser Val Ala Glu Val Cys Ile
                  80                  85                  90

 Thr Phe Asp Gln Ala Asn Leu Thr Val Lys Leu Pro Asp Gly Tyr
                  95                 100                 105

 Glu Phe Lys Phe Pro Asn Arg Leu Asn Leu Glu Ala Ile Asn Tyr
                 110                 115                 120

 Met Ala Ala Asp Gly Asp Phe Lys Ile Lys Cys Val Ala Phe Asp
                 125                 130                 135

<210> 207
<211> 1636
<212> DNA
<213> Homo sapien

<400> 207
 ggcacgaggc ttctgtgcgc tcgggctcct ggtcccggct ccccggttac 50

 cggggcgcga gtatgaccac aatggcggcc gccaccctgc tgcgcgcgac 100

 gccccacttc agcggtctcg ccgccggccg gaccttcctg ctgcagggtc 150

 tgttgcggct gctgaaagcc ccggcattgc ctctcttgtg ccgcggcctg 200

 gccgtggagg ccaagaagac ttacgtgcgc gacaagccac atgtgaatgt 250

 gggtaccatc ggccatgtgg accacgggaa gaccacgctg actgcagcca 300

 tcacgaagat tctagctgag ggaggtgggg ctaagttcaa gaagtacgag 350

 gagattgaca atgccccgga ggagcgagct cggggtatca ccatcaatgc 400

 ggctcatgtg gagtatagca ctgccgcccg ccactacgcc cacacagact 450

 gcccgggtca tgcagattat gttaagaata tgatcacagg cactgcaccc 500

 ctcgacggct gcatcctggt ggtagcagcc aatgacggcc ccatgcccca 550

 gacccgagag cacttattac tggccagaca gattggggtg gagcatgtgg 600

 tggtgtatgt gaacaaggct gacgctgtcc aggactctga gatggtggaa 650

 ctggtggaac tggagatccg ggagctgctc accgagtttg gctataaagg 700

 ggaggagacc ccagtcatcg taggctctgc tctctgtgcc cttgagggtc 750

 gggaccctga gttaggcctg aagtctgtgc agaagctact ggatgctgtg 800

 gacacttaca tcccagtgcc cgcccgggac ctggagaagc ctttcctgct 850

 gcctgtggag gcggtgtact ccgtccctgg ccgtggcacc gtggtgacag 900

 gtacactaga gcgtggcatt ttaaagaagg gagacgagtg tgagctccta 950

 ggacatagca agaacatccg cactgtggtg acaggcattg agatgttcca 1000

 caagagcctg gagagggccg aggccggaga taacctcggg gccctggtcc 1050

 gaggcttgaa gcgggaggac ttgcggcggg gcctggtcat ggtcaagcca 1100

 ggttccatca agccccacca gaaggtggag gcccaggttt acatcctcag 1150

 caaggaggaa ggtggccgcc acaagccctt tgtgtcccac ttcatgcctg 1200

 tcatgttctc cctgacttgg gacatggcct gtcggattat cctgccccca 1250

 gagaaggagc ttgccatgcc cggggaggac ctgaagttca acctaatctt 1300

 gcggcagcca atgatcttag agaaaggcca gcgtttcacc ctgcgagatg 1350

 gcaaccggac tattggcacc ggtctagtca ccaacacgct ggccatgact 1400

 gaggaggaga agaatatcaa atggggttga gtgtgcagat ctctgctcag 1450

 cttcccttgc gtttaaggcc tgccctagcc agggctccct cctgcttcca 1500

 gtaccctctc atggcatagg ctgcaaccca gcagagggca gctagatgga 1550

 catttcccct gctcggaagg gttggcctgc ctggctgggg aggtcagtaa 1600

 actttgaata gtaaaaaaaa aaaaaaaaaa aaaaaa 1636

<210> 208
<211> 452
<212> PRT
<213> Homo sapien

<400> 208
 Met Ala Ala Ala Thr Leu Leu Arg Ala Thr Pro His Phe Ser Gly
   1               5                  10                  15

 Leu Ala Ala Gly Arg Thr Phe Leu Leu Gln Gly Leu Leu Arg Leu
                  20                  25                  30

 Leu Lys Ala Pro Ala Leu Pro Leu Leu Cys Arg Gly Leu Ala Val
                  35                  40                  45

 Glu Ala Lys Lys Thr Tyr Val Arg Asp Lys Pro His Val Asn Val
                  50                  55                  60

 Gly Thr Ile Gly His Val Asp His Gly Lys Thr Thr Leu Thr Ala
                  65                  70                  75

 Ala Ile Thr Lys Ile Leu Ala Glu Gly Gly Gly Ala Lys Phe Lys
                  80                  85                  90

 Lys Tyr Glu Glu Ile Asp Asn Ala Pro Glu Glu Arg Ala Arg Gly
                  95                 100                 105

 Ile Thr Ile Asn Ala Ala His Val Glu Tyr Ser Thr Ala Ala Arg
                 110                 115                 120

 His Tyr Ala His Thr Asp Cys Pro Gly His Ala Asp Tyr Val Lys
                 125                 130                 135

 Asn Met Ile Thr Gly Thr Ala Pro Leu Asp Gly Cys Ile Leu Val
                 140                 145                 150

 Val Ala Ala Asn Asp Gly Pro Met Pro Gln Thr Arg Glu His Leu
                 155                 160                 165

 Leu Leu Ala Arg Gln Ile Gly Val Glu His Val Val Val Tyr Val
                 170                 175                 180

 Asn Lys Ala Asp Ala Val Gln Asp Ser Glu Met Val Glu Leu Val
                 185                 190                 195

 Glu Leu Glu Ile Arg Glu Leu Leu Thr Glu Phe Gly Tyr Lys Gly
                 200                 205                 210

 Glu Glu Thr Pro Val Ile Val Gly Ser Ala Leu Cys Ala Leu Glu
                 215                 220                 225

 Gly Arg Asp Pro Glu Leu Gly Leu Lys Ser Val Gln Lys Leu Leu
                 230                 235                 240

 Asp Ala Val Asp Thr Tyr Ile Pro Val Pro Ala Arg Asp Leu Glu
                 245                 250                 255

 Lys Pro Phe Leu Leu Pro Val Glu Ala Val Tyr Ser Val Pro Gly
                 260                 265                 270

 Arg Gly Thr Val Val Thr Gly Thr Leu Glu Arg Gly Ile Leu Lys
                 275                 280                 285

 Lys Gly Asp Glu Cys Glu Leu Leu Gly His Ser Lys Asn Ile Arg
                 290                 295                 300

 Thr Val Val Thr Gly Ile Glu Met Phe His Lys Ser Leu Glu Arg
                 305                 310                 315

 Ala Glu Ala Gly Asp Asn Leu Gly Ala Leu Val Arg Gly Leu Lys
                 320                 325                 330

 Arg Glu Asp Leu Arg Arg Gly Leu Val Met Val Lys Pro Gly Ser
                 335                 340                 345

 Ile Lys Pro His Gln Lys Val Glu Ala Gln Val Tyr Ile Leu Ser
                 350                 355                 360

 Lys Glu Glu Gly Gly Arg His Lys Pro Phe Val Ser His Phe Met
                 365                 370                 375

 Pro Val Met Phe Ser Leu Thr Trp Asp Met Ala Cys Arg Ile Ile
                 380                 385                 390

 Leu Pro Pro Glu Lys Glu Leu Ala Met Pro Gly Glu Asp Leu Lys
                 395                 400                 405

 Phe Asn Leu Ile Leu Arg Gln Pro Met Ile Leu Glu Lys Gly Gln
                 410                 415                 420

 Arg Phe Thr Leu Arg Asp Gly Asn Arg Thr Ile Gly Thr Gly Leu
                 425                 430                 435

 Val Thr Asn Thr Leu Ala Met Thr Glu Glu Glu Lys Asn Ile Lys
                 440                 445                 450

 Trp Gly


<210> 209
<211> 1299
<212> DNA
<213> Homo sapien

<400> 209
 ggcacgaggg cggcggcggc ggtagaggcg gcggcggcgg cggcagcggg 50

 ctcggaggca gcggttgggc tcgcggcgag cggacggggt cgagtcagtg 100

 cgttcgcgcg agttggaatc gaagcctctt aaaatggcag atgacttgga 150

 cttcgagaca ggagatgcag gggcctcagc caccttccca atgcagtgct 200

 cagcattacg taagaatggc tttgtggtgc tcaaaggccg gccatgtaag 250

 atcgtcgaga tgtctacttc gaagactggc aagcacggcc acgccaaggt 300

 ccatctggtt ggtattgaca tctttactgg gaagaaatat gaagatatct 350

 gcccgtcaac tcataatatg gatgtcccca acatcaaaag gaatgacttc 400

 cagctgattg gcatccagga tgggtaccta tcactgctcc aggacagcgg 450

 ggaggtacga gaggaccttc gtctccctga gggagacctt ggcaaggaga 500

 ttgagcagaa gtacgactgt ggagaagaga tcctgatcac ggtgctgtct 550

 gccatgacag aggaggcagc tgttgcaatc aaggccatgg caaaataact 600

 ggctcccagg atggcggtgg tggcagcagt gatcctctga acctgcagag 650

 gccccctccc cgagcctggc ctggctctgg cccggtccta agctggactc 700

 ctcctacaca atttatttga cgttttattt tggttttccc caccccctca 750

 atctgtcggg gagcccctgc ccttcaccta gctcccttgg ccaggagcga 800

 gcgaagctgt ggccttggtg aagctgccct cctcttctcc cctcacacta 850

 cagccctggt gggggagaag ggggtgggtg ctgcttgtgg tttagtcttt 900

 tttttttttt tttttttttt tttaaattca atctggaatc agaaagcggt 950

 ggattctggc aaatggtcct tgtgccctcc ccactcatcc ctggtctggt 1000

 cccctgttgc ccatagccct ttaccctgag caccacccca acagactggg 1050

 gaccagcccc ctcgcctgcc tgtgtctctc cccaaacccc tttagatggg 1100

 gagggaagag gaggagaggg gaggggacct gccccctcct caggcatctg 1150

 ggagggccct gcccccatgg gctttaccct tccctgcggg ctctctcccc 1200

 gacacatttg ttaaaatcaa acctgaataa aactacaagt ttaatatgaa 1250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1299

<210> 210
<211> 154
<212> PRT
<213> Homo sapien

<400> 210
 Met Ala Asp Asp Leu Asp Phe Glu Thr Gly Asp Ala Gly Ala Ser
   1               5                  10                  15

 Ala Thr Phe Pro Met Gln Cys Ser Ala Leu Arg Lys Asn Gly Phe
                  20                  25                  30

 Val Val Leu Lys Gly Arg Pro Cys Lys Ile Val Glu Met Ser Thr
                  35                  40                  45

 Ser Lys Thr Gly Lys His Gly His Ala Lys Val His Leu Val Gly
                  50                  55                  60

 Ile Asp Ile Phe Thr Gly Lys Lys Tyr Glu Asp Ile Cys Pro Ser
                  65                  70                  75

 Thr His Asn Met Asp Val Pro Asn Ile Lys Arg Asn Asp Phe Gln
                  80                  85                  90

 Leu Ile Gly Ile Gln Asp Gly Tyr Leu Ser Leu Leu Gln Asp Ser
                  95                 100                 105

 Gly Glu Val Arg Glu Asp Leu Arg Leu Pro Glu Gly Asp Leu Gly
                 110                 115                 120

 Lys Glu Ile Glu Gln Lys Tyr Asp Cys Gly Glu Glu Ile Leu Ile
                 125                 130                 135

 Thr Val Leu Ser Ala Met Thr Glu Glu Ala Ala Val Ala Ile Lys
                 140                 145                 150

 Ala Met Ala Lys


<210> 211
<211> 2937
<212> DNA
<213> Homo sapien

<400> 211
 gggttgcgcc agggagccgg aaagccgact cccgaagttg gggtcctggg 50

 aaaacttggg tcctgggttg actgagaagc ggcggggaaa ggaggcgggc 100

 caggaggagg gggcctggcg gacgccggcc ggggggcggg gcgcggcggg 150

 gctgtcggtc acgcccctca gtccgccccg ccccgccccg cctgccgggg 200

 aagggccacg ttgcccggcc cggccgtccg gccccggcgc gccgcagaaa 250

 gggctggcga gtcgaaaggc gaggcggccg cggcagcgct tgggacgcgc 300

 ctgggcaccg ggctcgctcc ctgcgccccg gagcaggcca agttcggggc 350

 caggacgtcg ggaggacctg gtgcatggct gcctcctaat cccatagtcc 400

 agaggaggca tccctaggac tgcgggcaag ggagccgggc aagcccaggg 450

 cagccttgaa ccgtcccctg gcctgccctc cccggtgggg gccaggatgc 500

 tgaagaagca gtctgcaggg cttgtgctgt ggggcgctat cctctttgtg 550

 gcctggaatg ccctgctgct cctcttcttc tggacgcgcc cagcacctgg 600

 caggccaccc tcagtcagcg ctctcgatgg cgaccccgcc agcctcaccc 650

 gggaagtgat tcgcctggcc caagacgccg aggtggagct ggagcggcag 700

 cgtgggctgc tgcagcagat cggggatgcc ctgtcgagcc agcgggggag 750

 ggtgcccacc gcggcccctc ccgcccagcc gcgtgtgcct gtgacccccg 800

 cgccggcggt gattcccatc ctggtcatcg cctgtgaccg cagcactgtt 850

 cggcgctgcc tggacaagct gctgcattat cggccctcgg ctgagctctt 900

 ccccatcatc gttagccagg actgcgggca cgaggagacg gcccaggcca 950

 tcgcctccta cggcagcgcg gtcacgcaca tccggcagcc cgacctgagc 1000

 agcattgcgg tgccgccgga ccaccgcaag ttccagggct actacaagat 1050

 cgcgcgccac taccgctggg cgctgggcca ggtcttccgg cagtttcgct 1100

 tccccgcggc cgtggtggtg gaggatgacc tggaggtggc cccggacttc 1150

 ttcgagtact ttcgggccac ctatccgctg ctgaaggccg acccctccct 1200

 gtggtgcgtc tcggcctgga atgacaacgg caaggagcag atggtggacg 1250

 ccagcaggcc tgagctgctc taccgcaccg actttttccc tggcctgggc 1300

 tggctgctgt tggccgagct ctgggctgag ctggagccca agtggccaaa 1350

 ggccttctgg gacgactgga tgcggcggcc ggagcagcgg caggggcggg 1400

 cctgcatacg ccctgagatc tcaagaacga tgacctttgg ccgcaagggt 1450

 gtgagccacg ggcagttctt tgaccagcac ctcaagttta tcaagctgaa 1500

 ccagcagttt gtgcacttca cccagctgga cctgtcttac ctgcagcggg 1550

 aggcctatga ccgagatttc ctcgcccgcg tctacggtgc tccccagctg 1600

 caggtggaga aagtgaggac caatgaccgg aaggagctgg gggaggtgcg 1650

 ggtgcagtat acgggcaggg acagcttcaa ggctttcgcc aaggctctgg 1700

 gtgtcatgga tgaccttaag tcgggggttc cgagagctgg ctaccggggt 1750

 attgtcacct tccagttccg gggccgccgt gtccacctgg cgcccccacc 1800

 gacgtgggag ggctatgatc ctagctggaa ttagcacctg cctgtccttc 1850

 ctgggcccct ccttgccaca tcatgagctg aggtgggacc acagtcccca 1900

 ggctgcatcg gcctgcctgt gtttccctct taggtgcatt tatctttttg 1950

 atttttccga gtggcattta agtgcacaaa tgataacaag aggattattc 2000

 tcccgttctc aagggagtca gatcagggga actattctag ggtatgttgc 2050

 ggggtattaa gcaggaaacc actgtgtggt ggggggcact gggcttgttg 2100

 gggccagaaa tgtccacgtc ctgagctttc tcctggagca tgtgcagaga 2150

 gtttggcaac gttcgctctc ttgaccagac cccttctccc tgacctggct 2200

 cttccagcca gggcacgagc cctccttcta tacctgctcc ccttccccca 2250

 gtggggactg agttatggga gaaggggaca tatttgtggc caaaatgata 2300

 ctaaccaaag gggcttcctt gtcagggcct ggtggagttg gtgggtcatc 2350

 ggggctcact gcctcctgcc cttctctcct gtctgacccc cacttagccc 2400

 ttctctcctt gcagcctagc agtttatagt tctgagatgg aaagttgaag 2450

 ggggcaagca agacctctcc tcagcccatg cccagctgtc aggagagagg 2500

 tgcagggagg aaggccttgt gctgggacaa cctctctctt gccttacctc 2550

 agagagggac tatgccctga cccctccttt ctgaaaatca gtgccctccc 2600

 tgttgctcta ggaggctcct gctggcttgg tagaagacag aattcgatct 2650

 gcctgtccct ttttcccctg gggtttgaca cacaggctcc tctcagcatg 2700

 aggtggagca gtgaccaggt ggagcagtga ccaggacgcc tctggcccag 2750

 tgctgcccag cctccccgcc cgctcccagg cgccccatgt cctcacaggc 2800

 caggacgcca tggcaggatg gagaggactt ggtggatttt tgtttcttgc 2850

 ctgacctcag tttcatgaaa gaaagtggaa gctacagaat tattttctaa 2900

 aataaaggct gaattgtctg aaaaaaaaaa aaaaaaa 2937

<210> 212
<211> 445
<212> PRT
<213> Homo sapien

<400> 212
 Met Leu Lys Lys Gln Ser Ala Gly Leu Val Leu Trp Gly Ala Ile
   1               5                  10                  15

 Leu Phe Val Ala Trp Asn Ala Leu Leu Leu Leu Phe Phe Trp Thr
                  20                  25                  30

 Arg Pro Ala Pro Gly Arg Pro Pro Ser Val Ser Ala Leu Asp Gly
                  35                  40                  45

 Asp Pro Ala Ser Leu Thr Arg Glu Val Ile Arg Leu Ala Gln Asp
                  50                  55                  60

 Ala Glu Val Glu Leu Glu Arg Gln Arg Gly Leu Leu Gln Gln Ile
                  65                  70                  75

 Gly Asp Ala Leu Ser Ser Gln Arg Gly Arg Val Pro Thr Ala Ala
                  80                  85                  90

 Pro Pro Ala Gln Pro Arg Val Pro Val Thr Pro Ala Pro Ala Val
                  95                 100                 105

 Ile Pro Ile Leu Val Ile Ala Cys Asp Arg Ser Thr Val Arg Arg
                 110                 115                 120

 Cys Leu Asp Lys Leu Leu His Tyr Arg Pro Ser Ala Glu Leu Phe
                 125                 130                 135

 Pro Ile Ile Val Ser Gln Asp Cys Gly His Glu Glu Thr Ala Gln
                 140                 145                 150

 Ala Ile Ala Ser Tyr Gly Ser Ala Val Thr His Ile Arg Gln Pro
                 155                 160                 165

 Asp Leu Ser Ser Ile Ala Val Pro Pro Asp His Arg Lys Phe Gln
                 170                 175                 180

 Gly Tyr Tyr Lys Ile Ala Arg His Tyr Arg Trp Ala Leu Gly Gln
                 185                 190                 195

 Val Phe Arg Gln Phe Arg Phe Pro Ala Ala Val Val Val Glu Asp
                 200                 205                 210

 Asp Leu Glu Val Ala Pro Asp Phe Phe Glu Tyr Phe Arg Ala Thr
                 215                 220                 225

 Tyr Pro Leu Leu Lys Ala Asp Pro Ser Leu Trp Cys Val Ser Ala
                 230                 235                 240

 Trp Asn Asp Asn Gly Lys Glu Gln Met Val Asp Ala Ser Arg Pro
                 245                 250                 255

 Glu Leu Leu Tyr Arg Thr Asp Phe Phe Pro Gly Leu Gly Trp Leu
                 260                 265                 270

 Leu Leu Ala Glu Leu Trp Ala Glu Leu Glu Pro Lys Trp Pro Lys
                 275                 280                 285

 Ala Phe Trp Asp Asp Trp Met Arg Arg Pro Glu Gln Arg Gln Gly
                 290                 295                 300

 Arg Ala Cys Ile Arg Pro Glu Ile Ser Arg Thr Met Thr Phe Gly
                 305                 310                 315

 Arg Lys Gly Val Ser His Gly Gln Phe Phe Asp Gln His Leu Lys
                 320                 325                 330

 Phe Ile Lys Leu Asn Gln Gln Phe Val His Phe Thr Gln Leu Asp
                 335                 340                 345

 Leu Ser Tyr Leu Gln Arg Glu Ala Tyr Asp Arg Asp Phe Leu Ala
                 350                 355                 360

 Arg Val Tyr Gly Ala Pro Gln Leu Gln Val Glu Lys Val Arg Thr
                 365                 370                 375

 Asn Asp Arg Lys Glu Leu Gly Glu Val Arg Val Gln Tyr Thr Gly
                 380                 385                 390

 Arg Asp Ser Phe Lys Ala Phe Ala Lys Ala Leu Gly Val Met Asp
                 395                 400                 405

 Asp Leu Lys Ser Gly Val Pro Arg Ala Gly Tyr Arg Gly Ile Val
                 410                 415                 420

 Thr Phe Gln Phe Arg Gly Arg Arg Val His Leu Ala Pro Pro Pro
                 425                 430                 435

 Thr Trp Glu Gly Tyr Asp Pro Ser Trp Asn
                 440                 445

<210> 213
<211> 2220
<212> DNA
<213> Homo sapien

<400> 213
 ggaaaattac ccggtatcgt tagagctaca ccaaaattgc attgagccaa 50

 acttgccacc aagagcccaa caatcaccat gatgctgagc acggaaggca 100

 gggaggggtt cgtggtgaag gtcaggggcc taccctggtc ctgctcagcc 150

 gatgaagtga tgcgcttctt ctctgattgc aagatccaaa atggcacatc 200

 aggtattcgt ttcatctaca ccagagaagg cagaccaagt ggtgaagcat 250

 ttgttgaact tgaatctgaa gaggaagtga aattggcttt gaagaaggac 300

 agagaaacca tgggacacag atacgttgaa gtattcaagt ctaacagtgt 350

 tgaaatggat tgggtgttga agcatacagg tccgaatagc cctgatactg 400

 ccaacgatgg cttcgtccgg cttagaggac tcccatttgg ctgtagcaag 450

 gaagagattg ttcagttctt ttcagggttg gaaattgtgc caaatgggat 500

 gacactgcca gtggactttc aggggcgaag cacaggggaa gcctttgtgc 550

 agtttgcttc acaggagata gctgagaagg ccttaaagaa acacaaggaa 600

 agaatagggc acaggtacat tgagatcttc aagagtagcc gagctgaagt 650

 tcgaacccac tatgatcccc ctcgaaagct catggctatg cagcggccag 700

 gtccctatga taggccgggg gctggcagag ggtataatag cattggcaga 750

 ggagctgggt ttgaaaggat gaggcgtggt gcctatggtg gagggtatgg 800

 aggctatgat gactatggtg gctataatga tggatatggc tttgggtctg 850

 atagatttgg aagagacctc aattactgtt tttcaggaat gtctgatcat 900

 agatacggag atggtgggtc cagtttccag agcaccacag ggcactgtgt 950

 acacatgagg gggttacctt acagagccac tgagaatgat atttataatt 1000

 tcttctcacc tcttaatccc atgagagtac atattgaaat tggacccgat 1050

 ggcagagtta ccggtgaggc agatgttgaa tttgctactc atgaagatgc 1100

 tgtggcagct atggcaaaag acaaagctaa tatgcaacac agatatgtgg 1150

 agctcttctt aaattctact gcaggaacaa gtgggggtgc ttacgatcac 1200

 agctatgtag aacttttttt gaattctaca gcaggggcaa gtggtggcgc 1250

 ttatggtagc caaatgatgg gagggatggg cttatccaac cagtctagtt 1300

 atggaggtcc tgctagccag cagctgagtg gtggttatgg aggtggttat 1350

 ggtggtcaga gcagtatgag tggatatgac caagttctgc aggaaaactc 1400

 cagtgactat cagtcaaacc ttgcttaggt agagaaggag cactaaatag 1450

 ctactccaga tataaaagct gtacatttgt gggagttgaa tagaatggga 1500

 gggatgttta gtatatccag tatgattggt aaatgggaaa tataattgat 1550

 tctgatcact cttggtcagc ttctctttct ttatctttct ttctcctttt 1600

 ttaagaaaac gagttaagtt taacagtttt gcattacagg cttgtgattc 1650

 atgcttactg taaagtggaa gttgagatta ttttaaaact tcaagctcag 1700

 taattttgaa cactgaaaca ttcatctagg acataataac aaagttcagt 1750

 attgaccata actgttaaaa caatttttag ctttcctcaa gttagttatg 1800

 ttgtaggagt gtacctaagc agtaagcgta tttaggttaa tgcagtttca 1850

 cttatgttaa atgttgctct tataccacaa atacattgaa aacttcggat 1900

 gcatgttgag aaacatgcct ttctgtaaaa ctcaaatata ggagctgtgt 1950

 ctacgattca aagtgaaaac atttggcatg tttgttaatt ctagcttttt 2000

 ggtttaatat cctgtaaggc acgtgagtgt acactttttt tttttttaag 2050

 gatacgggac aattttaaga tgtaatacca atactttaga agtttggtcg 2100

 tgtcgtttgt atgaaaatct gaggctttgg tttaaatctt tccttgtatt 2150

 gtgatttcca tttagatgta ttgtactaag tgaaacttgt taaataaatc 2200

 ttccttttaa aaactggaaa 2220

<210> 214
<211> 449
<212> PRT
<213> Homo sapien

<400> 214
 Met Met Leu Ser Thr Glu Gly Arg Glu Gly Phe Val Val Lys Val
   1               5                  10                  15

 Arg Gly Leu Pro Trp Ser Cys Ser Ala Asp Glu Val Met Arg Phe
                  20                  25                  30

 Phe Ser Asp Cys Lys Ile Gln Asn Gly Thr Ser Gly Ile Arg Phe
                  35                  40                  45

 Ile Tyr Thr Arg Glu Gly Arg Pro Ser Gly Glu Ala Phe Val Glu
                  50                  55                  60

 Leu Glu Ser Glu Glu Glu Val Lys Leu Ala Leu Lys Lys Asp Arg
                  65                  70                  75

 Glu Thr Met Gly His Arg Tyr Val Glu Val Phe Lys Ser Asn Ser
                  80                  85                  90

 Val Glu Met Asp Trp Val Leu Lys His Thr Gly Pro Asn Ser Pro
                  95                 100                 105

 Asp Thr Ala Asn Asp Gly Phe Val Arg Leu Arg Gly Leu Pro Phe
                 110                 115                 120

 Gly Cys Ser Lys Glu Glu Ile Val Gln Phe Phe Ser Gly Leu Glu
                 125                 130                 135

 Ile Val Pro Asn Gly Met Thr Leu Pro Val Asp Phe Gln Gly Arg
                 140                 145                 150

 Ser Thr Gly Glu Ala Phe Val Gln Phe Ala Ser Gln Glu Ile Ala
                 155                 160                 165

 Glu Lys Ala Leu Lys Lys His Lys Glu Arg Ile Gly His Arg Tyr
                 170                 175                 180

 Ile Glu Ile Phe Lys Ser Ser Arg Ala Glu Val Arg Thr His Tyr
                 185                 190                 195

 Asp Pro Pro Arg Lys Leu Met Ala Met Gln Arg Pro Gly Pro Tyr
                 200                 205                 210

 Asp Arg Pro Gly Ala Gly Arg Gly Tyr Asn Ser Ile Gly Arg Gly
                 215                 220                 225

 Ala Gly Phe Glu Arg Met Arg Arg Gly Ala Tyr Gly Gly Gly Tyr
                 230                 235                 240

 Gly Gly Tyr Asp Asp Tyr Gly Gly Tyr Asn Asp Gly Tyr Gly Phe
                 245                 250                 255

 Gly Ser Asp Arg Phe Gly Arg Asp Leu Asn Tyr Cys Phe Ser Gly
                 260                 265                 270

 Met Ser Asp His Arg Tyr Gly Asp Gly Gly Ser Ser Phe Gln Ser
                 275                 280                 285

 Thr Thr Gly His Cys Val His Met Arg Gly Leu Pro Tyr Arg Ala
                 290                 295                 300

 Thr Glu Asn Asp Ile Tyr Asn Phe Phe Ser Pro Leu Asn Pro Met
                 305                 310                 315

 Arg Val His Ile Glu Ile Gly Pro Asp Gly Arg Val Thr Gly Glu
                 320                 325                 330

 Ala Asp Val Glu Phe Ala Thr His Glu Asp Ala Val Ala Ala Met
                 335                 340                 345

 Ala Lys Asp Lys Ala Asn Met Gln His Arg Tyr Val Glu Leu Phe
                 350                 355                 360

 Leu Asn Ser Thr Ala Gly Thr Ser Gly Gly Ala Tyr Asp His Ser
                 365                 370                 375

 Tyr Val Glu Leu Phe Leu Asn Ser Thr Ala Gly Ala Ser Gly Gly
                 380                 385                 390

 Ala Tyr Gly Ser Gln Met Met Gly Gly Met Gly Leu Ser Asn Gln
                 395                 400                 405

 Ser Ser Tyr Gly Gly Pro Ala Ser Gln Gln Leu Ser Gly Gly Tyr
                 410                 415                 420

 Gly Gly Gly Tyr Gly Gly Gln Ser Ser Met Ser Gly Tyr Asp Gln
                 425                 430                 435

 Val Leu Gln Glu Asn Ser Ser Asp Tyr Gln Ser Asn Leu Ala
                 440                 445

<210> 215
<211> 4765
<212> DNA
<213> Homo sapien

<400> 215
 gttctcgctc cggagccgct gcacatttcg gaatcttctg cggcttgtcc 50

 atagtgtgaa taaaaactaa atcacatcta taattctact gaactggtca 100

 tacagacgct gccatatatg tcacagtaca ctgaaaagga gccagcagca 150

 atggaccaag aatctggtaa ggctgtctgg cccaaaccag caggagggta 200

 tcagacaatt acaggcagga gatatggaag aagacatgct tatgtcagtt 250

 ttaaaccatg tatgaccaga catgaaagaa gcttaggtcg ggctggtgat 300

 gactatgaag tgttggaact agatgatgtt ccaaaggaaa attcctcagg 350

 ttccagtcct ttggatcaag ttgattcttc tttacccagt gaacctatat 400

 ttgaaaaaag tgaaacagaa attcccactt gtggttcagc attgaatcaa 450

 accactgaga gcagtcaatc ctttgttgca gtacatcaca gtgaggaagg 500

 cagggatacc ttaggaagca gtacaaatct tcataatcac tctgagggag 550

 agtatattcc aggagcttgt agtgcttcaa gtgtccaaaa tggaattgca 600

 ttggttcata cagactctta tgatccagat ggcaaacatg gagaagataa 650

 tgaccatctt caactttctg cagaagtcgt ggaaggtagt agataccagg 700

 aatcattagg caatacagta tttgagttgg aaaacagaga ggcagaggca 750

 tacactggtc tttcaccacc agttccctca tttaactgtg aagtaagaga 800

 tgagtttgaa gagttagatt ctgtaccatt agtgaaaagt tctgctggtg 850

 atactgagtt tgtccatcag aatagccagg aaattcagag gtcttctcaa 900

 gatgaaatgg ttagtacgaa acaacaaaat aatactagcc aggaaagaca 950

 gacagaacat tcacctgaag atgcagcctg tggtccaggg catatttgta 1000

 gtgaacgaaa taccaatgat agggaaaaga accatggaag ttctcctgaa 1050

 caggtagtga ggccaaaagt tagaaaactg ataagttcaa gccaggtgga 1100

 ccaagaaaca ggttttaata ggcatgaggc gaaacaaaga agtgttcaaa 1150

 gatggagaga ggctttggaa gttgaggaaa gtggctcaga tgacctctta 1200

 ataaaatgtg aagaatatga tggagagcat gactgtatgt tcttggatcc 1250

 accatactca agagttatta cacaaaggga aacagaaaat aaccaaatga 1300

 catcagaaag tggagccaca gcgggaaggc aagaagtgga taacaccttt 1350

 tggaatggct gtggagatta ttaccaactc tatgacaaag atgaagatag 1400

 ttctgaatgc agtgatgggg aatggtctgc ttctttgcct catcgatttt 1450

 ctggtacaga aaaagatcaa tcctcaagtg atgaaagctg ggagactctg 1500

 ccaggaaaag atgagaatga acctgagcta caaagtgata gcagtggccc 1550

 tgaagaagaa aaccaagaat tatctcttca ggaaggggaa cagacatcct 1600

 tggaagaggg agaaattcct tggttacagt acaatgaagt caatgaaagc 1650

 agcagtgatg agggaaatga acctgccaat gaatttgcac agccagcttt 1700

 catgttggat ggtaacaata acctggagga tgactccagt gtgagtgaag 1750

 acttagatgt ggattggagc ctatttgatg gctttgcaga tggactagga 1800

 gttgctgaag ctatttcata tgtggatcct cagttcctta cctacatggc 1850

 actagaagaa cgcttagccc aggctatgga gactgctctg gcccatttag 1900

 agtctcttgc agtggatgtt gaggtggcca atccaccagc tagtaaggaa 1950

 agcattgatg gtcttccaga gacccttgtt cttgaagatc acactgctat 2000

 tggtcaggaa caatgctgtc caatctgttg cagtgagtat attaaggatg 2050

 atatagcaac agagttgccc tgtcaccatt tctttcacaa accttgtgtc 2100

 tcaatttggc tacaaaagtc gggaacatgc cctgtgtgcc gccgtcattt 2150

 cccacctgcg gttattgaag catctgcagc tccttcctct gagcctgatc 2200

 ctgatgcccc accttcaaat gacagtattg cagaagcacc ctaaaccttg 2250

 acagttgaaa tgagatcagt gtatcaaagt aaatctgcaa attccttcta 2300

 aatttcatgt gcaaataatt atatataaat atatttaaaa atgctatata 2350

 tagtatatgc catagtttag aaagaatatt aacctttcta aactaaattt 2400

 aggtttgcag aaagtattaa acatttttaa gctgaatgtt gagacagtgc 2450

 atccattttc tttagttgaa tatgtttgta ttaattgtaa agccaagctt 2500

 atcagttgac tctctccaga ataaataatc atctgtgtgg catacgttat 2550

 tggctttgtc tgtaatactg ccactaagtg attataatta agctgtcctg 2600

 tttgcatcaa atgtaaagac tgtgttcaca accgtagtaa aatttggttt 2650

 cattggaaat gaaacaaatt ctaaagtatg ctttttcact agtccctttg 2700

 attttgctat atcataacct cttggttcat atgctgagaa atttttcaga 2750

 aagtccattt ttgtttaaaa ttagaacttt tcagaatgcc aaatgaaggc 2800

 taaaattttg gccagaacat tacaaaagtt ttaaatcgta gacgtaactc 2850

 cccctgaaat aaagttaggt agtaaaatcc ttaatgaaac cagtggatgt 2900

 gcttaacgta aggttagtaa agcatacaaa gaatctagtg tgctcagggc 2950

 ttggtacaat gagctgaatt agatggcctt atgaaactct ttctaacctc 3000

 ttacccaacc tgtttctcct tggttaaaat tatacttgaa ggcccagaac 3050

 actcatggca catttgttta atattgctta tagttagttt aaggtaattt 3100

 tgcttctaca gtattttgga aggtctgaaa acttgcacag ggtcatcttt 3150

 gtaattatat aaccccaaac taagatgcac aatgtctcct tcaggtgatc 3200

 acacacagtg gacgagtatg tgcaaacatg gacataatag ttcacttaca 3250

 aatgtgattt gatgttaaca ctagagaatg atgactgtag aacatttgag 3300

 caagtaaaat agtaaagcac atagtgagtg tatgtccgtc taactggtac 3350

 attgataatt tagtttgggc acataaaagg aatatttata tggcttccca 3400

 aatgcagagt tacatcttat tcgtgtattt ctctgagtat ttatatcccg 3450

 tctccttttt tcattcttaa aaataaatga attttcactg ttggcacata 3500

 tgaggcttaa atataaggaa cataacactt gcattctaat ttttgcatat 3550

 attgtaaatg tgtctggtat ttacagcaaa atactgtgta tccttttatg 3600

 ggtaaaacaa aagtgaacat tgcatgcatg taatgtgatg aatttgtaat 3650

 ttaggagttc tttggggctt ctgtgacttg ggaaatgctt acattcaggc 3700

 cttaatgttg cattagctag catgttttcc ctctgatgta tatagtcact 3750

 gttgtataaa ctaatctttg cttgttttct actctgtgat ctttccatat 3800

 catatttcat taatgatcag ttagtgtcaa ggagtcaaaa cagattaaaa 3850

 ttaatttcat gtgtatatgg tggaaatttg tggctagtgt gatttttgtt 3900

 tgtttccttt taagtactgt tgatcagttg tgacacttac tggttaaact 3950

 tacgttgcta aagatttctc tataataagc cacacattat atttagacta 4000

 tattaaggga ccttggtttt cttctagata gcagctgtcc caaagaaaat 4050

 atttcttctt tgtctgttaa gatttagcta ttatctgcca gttgttaaga 4100

 ggttttggtt ccaaactcaa ccagcaatgt tgagagctga acttaagata 4150

 gctgttgtac tttttgcttt ccatctgtta ctgtccttca ttcttggctc 4200

 cctactatct ataaacagct gctgtgaaga agaaaagttg aataagagtt 4250

 ggcttaaatt ttaaaaaaga aaaagaaaat tgaggtttta ggattttcat 4300

 ggtaacaagc tctggtataa gctaaggctg gcaagttcag atactaaaat 4350

 attatttgat catatcttgg atccttttga aaaagttaag actatatgaa 4400

 ggtaaattag aaataagtat gaatattaat aaaatagcat ttatcttatt 4450

 tctctatttt atgttgtgac ttaacctaat tttatttttt taacattttc 4500

 ttatttctta taatatgaat gctgatattt aaaggtagat ctatgtggta 4550

 ttctttgtgt ttcttaattg tttaactctt aagattattt gtgatctgga 4600

 tttatgtatt tgttagatac atacgaattg ttaaaatgga atgcaagttt 4650

 ttcaaaagcc caggtctaaa tgtaatggtt ggtttattgt tctataaccc 4700

 cagcccatca ttttctgtgt aaatcataaa caataaacag aatatactcg 4750

 gtggtcattt ctaat 4765

<210> 216
<211> 708
<212> PRT
<213> Homo sapien

<400> 216
 Met Ser Gln Tyr Thr Glu Lys Glu Pro Ala Ala Met Asp Gln Glu
   1               5                  10                  15

 Ser Gly Lys Ala Val Trp Pro Lys Pro Ala Gly Gly Tyr Gln Thr
                  20                  25                  30

 Ile Thr Gly Arg Arg Tyr Gly Arg Arg His Ala Tyr Val Ser Phe
                  35                  40                  45

 Lys Pro Cys Met Thr Arg His Glu Arg Ser Leu Gly Arg Ala Gly
                  50                  55                  60

 Asp Asp Tyr Glu Val Leu Glu Leu Asp Asp Val Pro Lys Glu Asn
                  65                  70                  75

 Ser Ser Gly Ser Ser Pro Leu Asp Gln Val Asp Ser Ser Leu Pro
                  80                  85                  90

 Ser Glu Pro Ile Phe Glu Lys Ser Glu Thr Glu Ile Pro Thr Cys
                  95                 100                 105

 Gly Ser Ala Leu Asn Gln Thr Thr Glu Ser Ser Gln Ser Phe Val
                 110                 115                 120

 Ala Val His His Ser Glu Glu Gly Arg Asp Thr Leu Gly Ser Ser
                 125                 130                 135

 Thr Asn Leu His Asn His Ser Glu Gly Glu Tyr Ile Pro Gly Ala
                 140                 145                 150

 Cys Ser Ala Ser Ser Val Gln Asn Gly Ile Ala Leu Val His Thr
                 155                 160                 165

 Asp Ser Tyr Asp Pro Asp Gly Lys His Gly Glu Asp Asn Asp His
                 170                 175                 180

 Leu Gln Leu Ser Ala Glu Val Val Glu Gly Ser Arg Tyr Gln Glu
                 185                 190                 195

 Ser Leu Gly Asn Thr Val Phe Glu Leu Glu Asn Arg Glu Ala Glu
                 200                 205                 210

 Ala Tyr Thr Gly Leu Ser Pro Pro Val Pro Ser Phe Asn Cys Glu
                 215                 220                 225

 Val Arg Asp Glu Phe Glu Glu Leu Asp Ser Val Pro Leu Val Lys
                 230                 235                 240

 Ser Ser Ala Gly Asp Thr Glu Phe Val His Gln Asn Ser Gln Glu
                 245                 250                 255

 Ile Gln Arg Ser Ser Gln Asp Glu Met Val Ser Thr Lys Gln Gln
                 260                 265                 270

 Asn Asn Thr Ser Gln Glu Arg Gln Thr Glu His Ser Pro Glu Asp
                 275                 280                 285

 Ala Ala Cys Gly Pro Gly His Ile Cys Ser Glu Arg Asn Thr Asn
                 290                 295                 300

 Asp Arg Glu Lys Asn His Gly Ser Ser Pro Glu Gln Val Val Arg
                 305                 310                 315

 Pro Lys Val Arg Lys Leu Ile Ser Ser Ser Gln Val Asp Gln Glu
                 320                 325                 330

 Thr Gly Phe Asn Arg His Glu Ala Lys Gln Arg Ser Val Gln Arg
                 335                 340                 345

 Trp Arg Glu Ala Leu Glu Val Glu Glu Ser Gly Ser Asp Asp Leu
                 350                 355                 360

 Leu Ile Lys Cys Glu Glu Tyr Asp Gly Glu His Asp Cys Met Phe
                 365                 370                 375

 Leu Asp Pro Pro Tyr Ser Arg Val Ile Thr Gln Arg Glu Thr Glu
                 380                 385                 390

 Asn Asn Gln Met Thr Ser Glu Ser Gly Ala Thr Ala Gly Arg Gln
                 395                 400                 405

 Glu Val Asp Asn Thr Phe Trp Asn Gly Cys Gly Asp Tyr Tyr Gln
                 410                 415                 420

 Leu Tyr Asp Lys Asp Glu Asp Ser Ser Glu Cys Ser Asp Gly Glu
                 425                 430                 435

 Trp Ser Ala Ser Leu Pro His Arg Phe Ser Gly Thr Glu Lys Asp
                 440                 445                 450

 Gln Ser Ser Ser Asp Glu Ser Trp Glu Thr Leu Pro Gly Lys Asp
                 455                 460                 465

 Glu Asn Glu Pro Glu Leu Gln Ser Asp Ser Ser Gly Pro Glu Glu
                 470                 475                 480

 Glu Asn Gln Glu Leu Ser Leu Gln Glu Gly Glu Gln Thr Ser Leu
                 485                 490                 495

 Glu Glu Gly Glu Ile Pro Trp Leu Gln Tyr Asn Glu Val Asn Glu
                 500                 505                 510

 Ser Ser Ser Asp Glu Gly Asn Glu Pro Ala Asn Glu Phe Ala Gln
                 515                 520                 525

 Pro Ala Phe Met Leu Asp Gly Asn Asn Asn Leu Glu Asp Asp Ser
                 530                 535                 540

 Ser Val Ser Glu Asp Leu Asp Val Asp Trp Ser Leu Phe Asp Gly
                 545                 550                 555

 Phe Ala Asp Gly Leu Gly Val Ala Glu Ala Ile Ser Tyr Val Asp
                 560                 565                 570

 Pro Gln Phe Leu Thr Tyr Met Ala Leu Glu Glu Arg Leu Ala Gln
                 575                 580                 585

 Ala Met Glu Thr Ala Leu Ala His Leu Glu Ser Leu Ala Val Asp
                 590                 595                 600

 Val Glu Val Ala Asn Pro Pro Ala Ser Lys Glu Ser Ile Asp Gly
                 605                 610                 615

 Leu Pro Glu Thr Leu Val Leu Glu Asp His Thr Ala Ile Gly Gln
                 620                 625                 630

 Glu Gln Cys Cys Pro Ile Cys Cys Ser Glu Tyr Ile Lys Asp Asp
                 635                 640                 645

 Ile Ala Thr Glu Leu Pro Cys His His Phe Phe His Lys Pro Cys
                 650                 655                 660

 Val Ser Ile Trp Leu Gln Lys Ser Gly Thr Cys Pro Val Cys Arg
                 665                 670                 675

 Arg His Phe Pro Pro Ala Val Ile Glu Ala Ser Ala Ala Pro Ser
                 680                 685                 690

 Ser Glu Pro Asp Pro Asp Ala Pro Pro Ser Asn Asp Ser Ile Ala
                 695                 700                 705

 Glu Ala Pro


<210> 217
<211> 2992
<212> DNA
<213> Homo sapien

<400> 217
 ggcacgaggg gcggccggtg agggggaagc aagtctggtc tctgtgattg 50

 aagaagtcgg ctctgggctc cagtgcggga atcacacaca tacctcagaa 100

 tgccgggtct aagttgtaga ttttatcaac acaaatttcc tgaggtggaa 150

 gatgtagtga tggtgaatgt cagatccatt gctgaaatgg gggcttatgt 200

 cagcttgctg gaatacaaca acattgaagg catgattctt cttagtgaat 250

 tatccagaag gcgtatccgt tctatcaaca aactcatccg aattggcagg 300

 aatgagtgtg tggttgtcat tagggtggac aaagaaaaag gatatattga 350

 tttgtcaaaa agaagagttt ctccagagga agcaatcaaa tgtgaagaca 400

 aattcacaaa atccaaaact gtttatagca ttcttcgtca tgttgctgag 450

 gtgttagaat acaccaagga tgagcagctg gaaagcctat tccagaggac 500

 tgcctgggtc tttgatgaca agtacaagag acctggatat ggtgcctatg 550

 atgcatttaa gcatgcagtc tcagacccat ctattttgga tagtttagat 600

 ttgaatgaag atgaacggga agtactcatt aataatatta ataggcgctt 650

 gaccccacag gctgtcaaaa ttcgagcaga tattgaagtg gcttgttatg 700

 gttatgaagg cattgatgct gtaaaagaag ccctaagagc aggtttgaat 750

 tgttctacag aaaacatgcc cattaagatt aatctaatag ctcctcctcg 800

 gtatgtaatg actacgacaa ccctggagag aacagaaggc ctttctgtcc 850

 tcagtcaagc tatggctgtt atcaaagaga agattgagga aaagaggggt 900

 gtgttcaatg ttcaaatgga gcccaaagtg gtcacagata cagatgagac 950

 tgaacttgcg aggcagatgg agaggcttga aagagaaaat gccgaagtgg 1000

 atggagatga tgatgcagaa gaaatggaag ccaaagctga agattaactt 1050

 tgtgggaaac agagtccaat ttaaggaaca cagagcagcg cttcctggct 1100

 gtaaatccta gacttgaaag ttttccagta ttgaaaactt caaagctgaa 1150

 tattttttat ttctaagtat ttaaatgttc taacagatca gaacatgaaa 1200

 tgccctccta aatgtcagct gttgtcacac agtagctcca acactttgag 1250

 catttttaag ggagtggcct catttcacta gagacaaatc tttaagaata 1300

 gttctaaaat tgggcttgtg atttccattt ctgatgtctc cagattggca 1350

 cccctttcta gttcaatgcc tcacgagatt tgccaggggc atccaaggca 1400

 aacaatccca atctttctat ataaaatgta ttcaagcaaa catcaaataa 1450

 atttctggga tatttaacta taggcttctt ccttcttgtc accagttaaa 1500

 agcattttaa tactaagacc ctaattcttt tatctttatt ttagtcttga 1550

 tgtggaactg taggagcagg tgaataaagg atctctataa cagatccttt 1600

 caaaagaaga gttttagaga aaataaattt aactttaacc acagtgaaag 1650

 ttgaccctta gcgggacaaa gccttaaaat gcattgaaag aattagatcg 1700

 gttctgtgcc ttttatctat ttgagattga tgacaacctg tgtgagagaa 1750

 tttatcacac cacgtcctta ttggaataat aagctacttg ccttgagttt 1800

 ataattcagg gtggtaaagt atgtttttaa attttaaaaa gcagctgcat 1850

 tttttattta gttggaatat cacccaattt tttattttta ttgctattaa 1900

 aatatccact agatgccacc tagagctcca gttctttata acaaaacagg 1950

 gatctgtttg aacacttact gttgtttttt tttttttaca tgtttccatc 2000

 atttctgtct ttaagaacta attcgtacat aataagtttc ataggtaaca 2050

 cattatattc tcttatgata cttgaggtac cagttgtatt taattttatt 2100

 cattatccct agatagctat taagatactt agattagacc taacccacca 2150

 tagtcaatcc aagactagac tactcaatat taaagggtct ggaaaataga 2200

 agagtgtgtt gggcaggtag tttgtaccat ttatgaaggt ttgttccttt 2250

 gttaaattta gcagcctgta ctagcttttg aaatccagaa gttttaactt 2300

 ccagtggctg gtttctgaga gagtgccatg attgctagcc agcattccat 2350

 attgggaata tgtagaggag aacctggatg tacttaagag tggcatataa 2400

 ttttcacttc tgtctgttga ggcaaaaaaa aaacaagttt agaaagctgg 2450

 caacatgaag aatgcattca aaatataaca ggtgcttctt tgttgtacgc 2500

 agaggaattt tttcttttga ttttgtttac tgaaatttgt tatacttcaa 2550

 aagccataac ttgaaaaata ctggtggcgt cgatggtgag tgatttttat 2600

 cccacgtggg ccttttgctc agttccatgg caattttgta aattgaccct 2650

 agccagagaa tagatcagta tttcactgat accacgagga aaagaacaaa 2700

 caaaacttaa aagtattcat acaccttgct aacctaaaag acagcaggga 2750

 caagatacat atgaggacaa ggtatacacc cagttctgaa taacttgaag 2800

 aacaggcttg gcaaagaagt aagtttatcc aaatcttgaa tttctgccag 2850

 gcatggtagc tcatgcctgt aaccctggca cttaaggggc caaggcagga 2900

 ggatcacttg aggccagtga gctgtgatca ctccagtgca ctcgagcctg 2950

 ggtgacaggg caagaccctg tctcaaaaaa aaaaaaaaaa aa 2992

<210> 218
<211> 315
<212> PRT
<213> Homo sapien

<400> 218
 Met Pro Gly Leu Ser Cys Arg Phe Tyr Gln His Lys Phe Pro Glu
   1               5                  10                  15

 Val Glu Asp Val Val Met Val Asn Val Arg Ser Ile Ala Glu Met
                  20                  25                  30

 Gly Ala Tyr Val Ser Leu Leu Glu Tyr Asn Asn Ile Glu Gly Met
                  35                  40                  45

 Ile Leu Leu Ser Glu Leu Ser Arg Arg Arg Ile Arg Ser Ile Asn
                  50                  55                  60

 Lys Leu Ile Arg Ile Gly Arg Asn Glu Cys Val Val Val Ile Arg
                  65                  70                  75

 Val Asp Lys Glu Lys Gly Tyr Ile Asp Leu Ser Lys Arg Arg Val
                  80                  85                  90

 Ser Pro Glu Glu Ala Ile Lys Cys Glu Asp Lys Phe Thr Lys Ser
                  95                 100                 105

 Lys Thr Val Tyr Ser Ile Leu Arg His Val Ala Glu Val Leu Glu
                 110                 115                 120

 Tyr Thr Lys Asp Glu Gln Leu Glu Ser Leu Phe Gln Arg Thr Ala
                 125                 130                 135

 Trp Val Phe Asp Asp Lys Tyr Lys Arg Pro Gly Tyr Gly Ala Tyr
                 140                 145                 150

 Asp Ala Phe Lys His Ala Val Ser Asp Pro Ser Ile Leu Asp Ser
                 155                 160                 165

 Leu Asp Leu Asn Glu Asp Glu Arg Glu Val Leu Ile Asn Asn Ile
                 170                 175                 180

 Asn Arg Arg Leu Thr Pro Gln Ala Val Lys Ile Arg Ala Asp Ile
                 185                 190                 195

 Glu Val Ala Cys Tyr Gly Tyr Glu Gly Ile Asp Ala Val Lys Glu
                 200                 205                 210

 Ala Leu Arg Ala Gly Leu Asn Cys Ser Thr Glu Asn Met Pro Ile
                 215                 220                 225

 Lys Ile Asn Leu Ile Ala Pro Pro Arg Tyr Val Met Thr Thr Thr
                 230                 235                 240

 Thr Leu Glu Arg Thr Glu Gly Leu Ser Val Leu Ser Gln Ala Met
                 245                 250                 255

 Ala Val Ile Lys Glu Lys Ile Glu Glu Lys Arg Gly Val Phe Asn
                 260                 265                 270

 Val Gln Met Glu Pro Lys Val Val Thr Asp Thr Asp Glu Thr Glu
                 275                 280                 285

 Leu Ala Arg Gln Met Glu Arg Leu Glu Arg Glu Asn Ala Glu Val
                 290                 295                 300

 Asp Gly Asp Asp Asp Ala Glu Glu Met Glu Ala Lys Ala Glu Asp
                 305                 310                 315

<210> 219
<211> 1449
<212> DNA
<213> Homo sapien

<400> 219
 cttttcctgt ggcagcagcc gggctgagag gagcgtggct gtctcctctc 50

 tccgccatgg cgtgtgctcg cccactgata tcggtgtact ccgaaaaggg 100

 ggagtcatct ggcaaaaatg tcactttgcc tgctgtattc aaggctccta 150

 ttcgaccaga tattgtgaac tttgttcaca ccaacttgcg caaaaacaac 200

 agacagccct atgctgtcag tgaattagca ggtcatcaga ctagtgctga 250

 gtcttggggt actggcagag ctgtggctcg aattcccaga gttcgaggtg 300

 gtgggactca ccgctctggc cagggtgctt ttggaaacat gtgtcgtgga 350

 ggccgaatgt ttgcaccaac caaaacctgg cgccgttggc atcgtagagt 400

 gaacacaacc caaaaacgat acgccatctg ttctgccctg gctgcctcag 450

 ccctaccagc actggtcatg tctaaaggtc atcgtattga ggaagttcct 500

 gaacttcctt tggtagttga agataaagtt gaaggctaca agaagaccaa 550

 ggaagctgtt ttgctcctta agaaacttaa agcctggaat gatatcaaaa 600

 aggtctatgc ctctcagcga atgagagctg gcaaaggcaa aatgagaaac 650

 cgtcgccgta tccagcgcag gggcccgtgc atcatctata atgaggataa 700

 tggtatcatc aaggccttca gaaacatccc tggaattact ctgcttaatg 750

 taagcaagct gaacattttg aagcttgctc ctggtgggca tgtgggacgt 800

 ttctgcattt ggactgaaag tgctttccgg aagttagatg aattgtacgg 850

 cacttggcgt aaagccgctt ccctcaagag taactacaat cttcccatgc 900

 acaagatgat taatacagat cttagcagaa tcttgaaaag cccagagatc 950

 caaagagccc ttcgagcacc acgcaagaag atccatcgca gagtcctaaa 1000

 gaagaaccca ctgaaaaact tgagaatcat gttgaagcta aacccatatg 1050

 caaagaccat gcgccggaac accattcttc gccaggccag gaatcacaag 1100

 ctccgggtgg ataaggcagc tgctgcagca gcggcactac aagccaaatc 1150

 agatgagaag gcggcggttg caggcaagaa gcctgtggta ggtaagaaag 1200

 gaaagaaggc tgctgttggt gttaagaagc agaagaagcc tctggtggga 1250

 aaaaaggcag cagctaccaa gaaaccagcc cctgaaaaga agcctgcaga 1300

 gaagaaacct actacagagg agaagaagcc tgctgcataa actcttaaat 1350

 ttgattattc cataaaggtc aaatcatttt ggacagcttc ttttgaataa 1400

 agacctgatt atacaggcag tgagaaacat gaaaaaaaaa aaaaaaaaa 1449

<210> 220
<211> 427
<212> PRT
<213> Homo sapien

<400> 220
 Met Ala Cys Ala Arg Pro Leu Ile Ser Val Tyr Ser Glu Lys Gly
   1               5                  10                  15

 Glu Ser Ser Gly Lys Asn Val Thr Leu Pro Ala Val Phe Lys Ala
                  20                  25                  30

 Pro Ile Arg Pro Asp Ile Val Asn Phe Val His Thr Asn Leu Arg
                  35                  40                  45

 Lys Asn Asn Arg Gln Pro Tyr Ala Val Ser Glu Leu Ala Gly His
                  50                  55                  60

 Gln Thr Ser Ala Glu Ser Trp Gly Thr Gly Arg Ala Val Ala Arg
                  65                  70                  75

 Ile Pro Arg Val Arg Gly Gly Gly Thr His Arg Ser Gly Gln Gly
                  80                  85                  90

 Ala Phe Gly Asn Met Cys Arg Gly Gly Arg Met Phe Ala Pro Thr
                  95                 100                 105

 Lys Thr Trp Arg Arg Trp His Arg Arg Val Asn Thr Thr Gln Lys
                 110                 115                 120

 Arg Tyr Ala Ile Cys Ser Ala Leu Ala Ala Ser Ala Leu Pro Ala
                 125                 130                 135

 Leu Val Met Ser Lys Gly His Arg Ile Glu Glu Val Pro Glu Leu
                 140                 145                 150

 Pro Leu Val Val Glu Asp Lys Val Glu Gly Tyr Lys Lys Thr Lys
                 155                 160                 165

 Glu Ala Val Leu Leu Leu Lys Lys Leu Lys Ala Trp Asn Asp Ile
                 170                 175                 180

 Lys Lys Val Tyr Ala Ser Gln Arg Met Arg Ala Gly Lys Gly Lys
                 185                 190                 195

 Met Arg Asn Arg Arg Arg Ile Gln Arg Arg Gly Pro Cys Ile Ile
                 200                 205                 210

 Tyr Asn Glu Asp Asn Gly Ile Ile Lys Ala Phe Arg Asn Ile Pro
                 215                 220                 225

 Gly Ile Thr Leu Leu Asn Val Ser Lys Leu Asn Ile Leu Lys Leu
                 230                 235                 240

 Ala Pro Gly Gly His Val Gly Arg Phe Cys Ile Trp Thr Glu Ser
                 245                 250                 255

 Ala Phe Arg Lys Leu Asp Glu Leu Tyr Gly Thr Trp Arg Lys Ala
                 260                 265                 270

 Ala Ser Leu Lys Ser Asn Tyr Asn Leu Pro Met His Lys Met Ile
                 275                 280                 285

 Asn Thr Asp Leu Ser Arg Ile Leu Lys Ser Pro Glu Ile Gln Arg
                 290                 295                 300

 Ala Leu Arg Ala Pro Arg Lys Lys Ile His Arg Arg Val Leu Lys
                 305                 310                 315

 Lys Asn Pro Leu Lys Asn Leu Arg Ile Met Leu Lys Leu Asn Pro
                 320                 325                 330

 Tyr Ala Lys Thr Met Arg Arg Asn Thr Ile Leu Arg Gln Ala Arg
                 335                 340                 345

 Asn His Lys Leu Arg Val Asp Lys Ala Ala Ala Ala Ala Ala Ala
                 350                 355                 360

 Leu Gln Ala Lys Ser Asp Glu Lys Ala Ala Val Ala Gly Lys Lys
                 365                 370                 375

 Pro Val Val Gly Lys Lys Gly Lys Lys Ala Ala Val Gly Val Lys
                 380                 385                 390

 Lys Gln Lys Lys Pro Leu Val Gly Lys Lys Ala Ala Ala Thr Lys
                 395                 400                 405

 Lys Pro Ala Pro Glu Lys Lys Pro Ala Glu Lys Lys Pro Thr Thr
                 410                 415                 420

 Glu Glu Lys Lys Pro Ala Ala
                 425

<210> 221
<211> 4912
<212> DNA
<213> Homo sapien

<400> 221
 ggcacgaggc tgctctcgca actcaagatg gcggacgaga gtgagacagc 50

 agtgaagccg ccggcacctc cgctgccgca gatgatggaa gggaacggga 100

 acggccatga gcactgcagc gattgcgaga atgaggagga caacagctac 150

 aaccggggtg gtttgagtcc agccaatgac actggagcca aaaagaagaa 200

 aaagaaacaa aaaaagaaga aagaaaaagg cagtgagaca gattcagccc 250

 aggatcagcc tgtgaagatg aactctttgc cagcagagag gatccaggaa 300

 atacagaagg ccattgagct gttctcagtg ggtcagggac ctgccaaaac 350

 catggaggag gctagcaagc gaagctacca gttctgggat acgcagcccg 400

 tccccaagct gggcgaagtg gtgaacaccc atggccccgt ggagcctgac 450

 aaggacaata tccgccagga gccctacacc ctgccccagg gcttcacctg 500

 ggatgctttg gacttgggcg atcgtggtgt gctaaaagaa ctgtacaccc 550

 tcctgaatga gaactatgtg gaagatgatg acaacatgtt ccgatttgat 600

 tattccccgg agtttctttt gtgggctctc cggccacccg gctggctccc 650

 ccagtggcac tgtggggttc gagtggtctc aagtcggaaa ttggttgggt 700

 tcattagcgc catcccagca aacatccata tctatgacac agagaagaag 750

 atggtagaga tcaacttcct gtgtgtccac aagaagctgc gttccaagag 800

 ggttgctcca gttctgatcc gagagatcac caggcgggtt cacctggagg 850

 gcatcttcca agcagtttac actgccgggg tggtactacc aaagcccgtt 900

 ggcacctgca ggtattggca tcggtcccta aacccacgga agctgattga 950

 agtgaagttc tcccacctga gcagaaatat gaccatgcag cgcaccatga 1000

 agctctaccg actgccagag actcccaaga cagctgggct gcgaccaatg 1050

 gaaacaaagg acattccagt agtgcaccag ctcctcacca ggtacttgaa 1100

 gcaatttcac cttacgcccg tcatgagcca ggaggaggtg gagcactggt 1150

 tctaccccca ggagaatatc atcgacactt tcgtggtgga gaacgcaaac 1200

 ggagaggtga cagatttcct gagcttttat acgctgccct ccaccatcat 1250

 gaaccatcca acccacaaga gtctcaaagc tgcttattct ttctacaacg 1300

 ttcacaccca gacccctctt ctagacctca tgagcgacgc ccttgtcctc 1350

 gccaaaatga aagggtttga tgtgttcaat gcactggatc tcatggagaa 1400

 caaaaccttc ctggagaagc tcaagtttgg cataggggac ggcaacctgc 1450

 agtattacct ttacaattgg aaatgcccca gcatgggggc agagaaggtt 1500

 ggactggtgc tacaataacc agtcaccagt gcgattctgg ataaagccac 1550

 tgaaaattcg aaccaggaaa tggaacccca ccactgttgg tccaattttc 1600

 acacacgtga gaatccctgg caaagggagc agaactgaac cggctttacc 1650

 aaaccgccag cgaacttgac aattgtattg cgatggcgtg ggctgcgtga 1700

 cgtcacctcc ggtcgtgtct ctggtctccg tgttttccag ttaattacat 1750

 cctcatgcag ccgtgatcaa gggaatgtaa ctgctgaaaa ctagctcgtg 1800

 attggcatat aatggagtta acgggtgaat aataaaagta tatatatata 1850

 ttatatatat ataaatattt taaatatctt tcatgttcca aatgtacaag 1900

 gatgtttggt ctttaatgaa aagctgaatc tagatcattc ctcagaatga 1950

 ggacccgagg acagtggcag acagacgcgt tggcacagtt catggtttcc 2000

 tccagaggag acattggctt atcatgggga aaaagaggat ctggagaacc 2050

 tcatccagct ccccttctga atcagctggg atgactggct ttgagaagga 2100

 agggaagatg gaacaggctc agatctcatg ggatagcacg tggagctctt 2150

 ggctggggct gaccctgggc agggactttc ctgcagggcc agacctgcct 2200

 gcattctgag acaaagcaat ggacggtccg cagaagcaga cctcattgat 2250

 tgagtccttt cttccatccc cttggcctgc tccctgtagg aagtcatcct 2300

 gccaactgat ttaaaagggc tctttagcca gttgttgcca accttatagg 2350

 gatgagtccc ctgtgagatt ttgcttttcc actgcctggg atgatgcagt 2400

 ttgaagaggc ccttggacct ccttgtaaca tcagggacct ttggagacca 2450

 ttatcagtgt aagccctgct tagctcatct tagagcaaag agccagcacc 2500

 ctgatgtccc tggggtggct aggcaggagt ggcgtggggc caatacccag 2550

 accccttcag ccaccagccc ctggcctgtg ccttccaacc cattagccat 2600

 ttcttgttgt gcccctttcc aagatacagc ctgcaagtgg tagcaagaag 2650

 tgattagagg cagatctgga cttggcaaca gaagtggttt cccatctcca 2700

 ttgtctgagt ctgattttcg ctgatgctgt tttgtggatt tttgtggtag 2750

 tgatggttgt cagtgctgcc agtttcccaa aacgtaatca agcctctggt 2800

 cacatggctg tcgatgtagg cattctggag tggtgttcag ccaagtgacc 2850

 gggcaaaatt gggctgtgaa attgtacttc caggcttgga tgtaattttt 2900

 gctctagaga gaagcaagtg gtgggaagga ggtagcatga cgtgtggtgt 2950

 gcgggtttcc ttgctgccgt cacctctccg ctcatacagg aatgaagcct 3000

 tagccaggag gccaggctca gccctgtgcc actcaccgaa gccactttct 3050

 acaggccagc aggggcttgt tgcaggctgt gggttttggt gtggtttgtc 3100

 agaggctaat tctgcagagt ttccaaaacc agaagacatc gtatgcttgg 3150

 gatgggggcc gtgccacccg tgggaatgct gcccgctctg cagactgctg 3200

 ctagagccag caactccact aaggtggatt ttcatcaggg gcctgcaggg 3250

 ccctcccttt tcccattgtt cctgcgctgc aaattgcagg ccccagcaat 3300

 cgtgactgac gtttgctcct tgactccaag aaactgagac caaagaagct 3350

 gctgttctta gcaagatgcg cactgcattc cacaggtggg aggagtcgga 3400

 gaggcagggg cttgctttgc agccccacag acaacagttg cacagtgcct 3450

 caagccccag agtggctcac cctgtccaga cctttgagga tatcaaagga 3500

 caaagtgccc aagtctttcc taccttgggg gaacctggaa cttggaaagg 3550

 ctccctgtcc tagtcttgat ctgttctggg ccaggtccca gcttgagctg 3600

 cctctgagat ttgggctgtg cggatctctg gagtgagctc tgtttcggtt 3650

 gacccaggtc atggaatgga aacggtgagg ccccagtggc tgttctggaa 3700

 gaaacagatc tcctggcaaa ggccccagca tctccctcac tgaaaccagg 3750

 tggccggctc ctcggactct gctttatgtt gcggtgagaa ctctgcccag 3800

 gtgtgcaggg tttggcttgt gggctgcttg ctgctcatct gatttttgtc 3850

 ccagtagtcc ctgcgttctt cattcaaccc cttctgggac ttcagctcag 3900

 agagcaccat cccgggggtc agggcctccc cacaggagcc ctgcagtgtg 3950

 gtagcgccat ggctgtctca aaccaagcaa aggaaggacc ctgaggcctt 4000

 cacgctaacc atcctcgagc aactgctgtt ggaaggcctc cctgggcctg 4050

 gcccccaccc tctgccaccc agtcctccca gctgccatgt ttcaaagacg 4100

 acctttacct cctgcctttg gattgactct gcatttgacc acggactcca 4150

 gtctgtgtgt agggagagag ctgagtagga ggcctccact ccggatcgag 4200

 gcctgtatag ggctcgtttc cccacacatg cctatttctg aagaggcttc 4250

 tgtcttattt gaaggccagc ccacacccag ctactttaac accaggttta 4300

 tggaaaatgt caggccttcc ccacaactcc tgtctaactg ctgtcgcccc 4350

 cctacttgct ggctctcaga agcctagggg agtccctgtg gtcctgaatt 4400

 ctttccccaa agacgaccag catttaacca acctaagggc ccaaaggcct 4450

 tggacaactg catggagctg cactctagga gaaggagggg aaccagatgt 4500

 tagatcaggg gagggagcag gagtgtccct cccgtcagtg cctacccacc 4550

 tgtgaggcag ccttctgatg gcctggccca ccttccccag aaccagggga 4600

 ggcctgaggc ttcagtttta ctctgctgca aaatgaaggc gggcctgcaa 4650

 gccgactaca cctacggagg ctgttgagga caatttcatt ccattaaatt 4700

 aaaaaatact gactggctgg caggcaggtg ccatgtctgg gaacagggac 4750

 gggggagctt cacctttttg tcttggcttt tctttgggct gtgggggggc 4800

 atccatttcc agggtcgggg aggaaatacc aaatgcattg ttgttctgct 4850

 caatacatct cacttgtttc taataaagaa agcagctgaa caaaaaaaaa 4900

 aaaaaaaaaa aa 4912

<210> 222
<211> 496
<212> PRT
<213> Homo sapien

<400> 222
 Met Ala Asp Glu Ser Glu Thr Ala Val Lys Pro Pro Ala Pro Pro
   1               5                  10                  15

 Leu Pro Gln Met Met Glu Gly Asn Gly Asn Gly His Glu His Cys
                  20                  25                  30

 Ser Asp Cys Glu Asn Glu Glu Asp Asn Ser Tyr Asn Arg Gly Gly
                  35                  40                  45

 Leu Ser Pro Ala Asn Asp Thr Gly Ala Lys Lys Lys Lys Lys Lys
                  50                  55                  60

 Gln Lys Lys Lys Lys Glu Lys Gly Ser Glu Thr Asp Ser Ala Gln
                  65                  70                  75

 Asp Gln Pro Val Lys Met Asn Ser Leu Pro Ala Glu Arg Ile Gln
                  80                  85                  90

 Glu Ile Gln Lys Ala Ile Glu Leu Phe Ser Val Gly Gln Gly Pro
                  95                 100                 105

 Ala Lys Thr Met Glu Glu Ala Ser Lys Arg Ser Tyr Gln Phe Trp
                 110                 115                 120

 Asp Thr Gln Pro Val Pro Lys Leu Gly Glu Val Val Asn Thr His
                 125                 130                 135

 Gly Pro Val Glu Pro Asp Lys Asp Asn Ile Arg Gln Glu Pro Tyr
                 140                 145                 150

 Thr Leu Pro Gln Gly Phe Thr Trp Asp Ala Leu Asp Leu Gly Asp
                 155                 160                 165

 Arg Gly Val Leu Lys Glu Leu Tyr Thr Leu Leu Asn Glu Asn Tyr
                 170                 175                 180

 Val Glu Asp Asp Asp Asn Met Phe Arg Phe Asp Tyr Ser Pro Glu
                 185                 190                 195

 Phe Leu Leu Trp Ala Leu Arg Pro Pro Gly Trp Leu Pro Gln Trp
                 200                 205                 210

 His Cys Gly Val Arg Val Val Ser Ser Arg Lys Leu Val Gly Phe
                 215                 220                 225

 Ile Ser Ala Ile Pro Ala Asn Ile His Ile Tyr Asp Thr Glu Lys
                 230                 235                 240

 Lys Met Val Glu Ile Asn Phe Leu Cys Val His Lys Lys Leu Arg
                 245                 250                 255

 Ser Lys Arg Val Ala Pro Val Leu Ile Arg Glu Ile Thr Arg Arg
                 260                 265                 270

 Val His Leu Glu Gly Ile Phe Gln Ala Val Tyr Thr Ala Gly Val
                 275                 280                 285

 Val Leu Pro Lys Pro Val Gly Thr Cys Arg Tyr Trp His Arg Ser
                 290                 295                 300

 Leu Asn Pro Arg Lys Leu Ile Glu Val Lys Phe Ser His Leu Ser
                 305                 310                 315

 Arg Asn Met Thr Met Gln Arg Thr Met Lys Leu Tyr Arg Leu Pro
                 320                 325                 330

 Glu Thr Pro Lys Thr Ala Gly Leu Arg Pro Met Glu Thr Lys Asp
                 335                 340                 345

 Ile Pro Val Val His Gln Leu Leu Thr Arg Tyr Leu Lys Gln Phe
                 350                 355                 360

 His Leu Thr Pro Val Met Ser Gln Glu Glu Val Glu His Trp Phe
                 365                 370                 375

 Tyr Pro Gln Glu Asn Ile Ile Asp Thr Phe Val Val Glu Asn Ala
                 380                 385                 390

 Asn Gly Glu Val Thr Asp Phe Leu Ser Phe Tyr Thr Leu Pro Ser
                 395                 400                 405

 Thr Ile Met Asn His Pro Thr His Lys Ser Leu Lys Ala Ala Tyr
                 410                 415                 420

 Ser Phe Tyr Asn Val His Thr Gln Thr Pro Leu Leu Asp Leu Met
                 425                 430                 435

 Ser Asp Ala Leu Val Leu Ala Lys Met Lys Gly Phe Asp Val Phe
                 440                 445                 450

 Asn Ala Leu Asp Leu Met Glu Asn Lys Thr Phe Leu Glu Lys Leu
                 455                 460                 465

 Lys Phe Gly Ile Gly Asp Gly Asn Leu Gln Tyr Tyr Leu Tyr Asn
                 470                 475                 480

 Trp Lys Cys Pro Ser Met Gly Ala Glu Lys Val Gly Leu Val Leu
                 485                 490                 495

 Gln


<210> 223
<211> 1931
<212> DNA
<213> Homo sapien

<400> 223
 gcccaagagc gagcgcgcag cacgaagctc gagccgcctc cgccgcgcga 50

 ccccacctcg gccgccgccg cctgcgccgc gagatccgcc ccggcctccc 100

 cgagagcgag ccccggccgc cgcgaccacc agccgcgcta accgccgacc 150

 aaccgccacc gaggcgcctg agcgagagca gaggaggagg aggcatgagt 200

 gaggcgggcg aggccaccac caccaccacc accaccctcc cgcaggctcc 250

 gacggaggcg gccgccgcgg ctccccagga ccccgcgccc aagagcccgg 300

 tgggcagcgg tgcgccccag gccgcggccc cggcgcccgc cgcccacgtc 350

 gcaggaaacc ccggtgggga cgcggccccc gcagccacgg gcaccgcggc 400

 cgccgcctct ttagccgccg ccgccggcag cgaagacgcg gagaaaaaag 450

 ttctcgccac caaagtcctt ggcactgtca aatggttcaa cgtcagaaat 500

 ggatatggat ttataaatcg aaatgacacc aaagaagatg tatttgtaca 550

 tcagactgcc atcaagaaga ataacccacg gaaatatctg cgcagtgtag 600

 gagatggaga aactgtagag tttgatgtgg ttgaaggaga gaagggtgca 650

 gaagctgcca atgtgactgg cccggatgga gttcctgtgg aagggagtcg 700

 ttacgctgca gatcggcgcc gttacagacg tggctactat ggaaggcgcc 750

 gtggccctcc ccggaattac gctggggagg aggaggagga agggagcggc 800

 agcagtgaag gatttgaccc ccctgccact gataggcagt tctctggggc 850

 ccggaatcag ctgcgccgcc cccagtatcg ccctcagtac cggcagcggc 900

 ggttcccgcc ttaccacgtg ggacagacct ttgaccgtcg ctcacgggtc 950

 ttaccccatc ccaacagaat acaggctggt gagattggag agatgaagga 1000

 tggagtccca gagggagcac aacttcaggg accggttcat cgaaatccaa 1050

 cttaccgccc aaggtaccgt agcaggggac ctcctcgccc acgacctgcc 1100

 ccagcagttg gagaggctga agataaagaa aatcagcaag ccaccagtgg 1150

 tccaaaccag ccgtctgttc gccgtggata tcggcgtccc tacaattacc 1200

 ggcgtcgccc gcgtcctcct aacgctcctt cacaagatgg caaagaggcc 1250

 aaggcaggtg aagcaccaac tgagaaccct gctccaccca cccagcagag 1300

 cagtgctgag taacaccagg ctcctcaggc accttcacca tcggcaggtg 1350

 acctaaagaa ttaatgacca ttcagaaata aagcaaaaag caggccacaa 1400

 ccttaaccaa caccaaagaa acatccaagc aataaagtgg aagactaacc 1450

 aagatttgga cattggaatg tttactgtta ttctttaaga aacatctaca 1500

 aaaagaaaat gtcaacaaat ttttccagca agctgagaac ctgggaattc 1550

 ctgcacggaa gacaagagag tagcctctcc agtttcagca accgctaggt 1600

 ttctattttt tttcctggtt tttactgttt tggtaatata tatattgaaa 1650

 caagaaatat taataccaca tggggagaac cccaaccaaa gaaatctgaa 1700

 atatatagta aatgcttttt tttccgtttt tgttcatttt ggatgctggt 1750

 gctaaacctc caagtgtcat gatttaaaaa aaaaaaaaat ttatgtcctt 1800

 cttatttatt tctaggatga ggggaggata acatttttgc tttcttatgt 1850

 gactctcttt gaaaatgtgc agtaagaaat tcctcaaaaa taaaattttt 1900

 acccttcaga ggaaaaaaaa aaaaaaaaaa a 1931

<210> 224
<211> 372
<212> PRT
<213> Homo sapien

<400> 224
 Met Ser Glu Ala Gly Glu Ala Thr Thr Thr Thr Thr Thr Thr Leu
   1               5                  10                  15

 Pro Gln Ala Pro Thr Glu Ala Ala Ala Ala Ala Pro Gln Asp Pro
                  20                  25                  30

 Ala Pro Lys Ser Pro Val Gly Ser Gly Ala Pro Gln Ala Ala Ala
                  35                  40                  45

 Pro Ala Pro Ala Ala His Val Ala Gly Asn Pro Gly Gly Asp Ala
                  50                  55                  60

 Ala Pro Ala Ala Thr Gly Thr Ala Ala Ala Ala Ser Leu Ala Ala
                  65                  70                  75

 Ala Ala Gly Ser Glu Asp Ala Glu Lys Lys Val Leu Ala Thr Lys
                  80                  85                  90

 Val Leu Gly Thr Val Lys Trp Phe Asn Val Arg Asn Gly Tyr Gly
                  95                 100                 105

 Phe Ile Asn Arg Asn Asp Thr Lys Glu Asp Val Phe Val His Gln
                 110                 115                 120

 Thr Ala Ile Lys Lys Asn Asn Pro Arg Lys Tyr Leu Arg Ser Val
                 125                 130                 135

 Gly Asp Gly Glu Thr Val Glu Phe Asp Val Val Glu Gly Glu Lys
                 140                 145                 150

 Gly Ala Glu Ala Ala Asn Val Thr Gly Pro Asp Gly Val Pro Val
                 155                 160                 165

 Glu Gly Ser Arg Tyr Ala Ala Asp Arg Arg Arg Tyr Arg Arg Gly
                 170                 175                 180

 Tyr Tyr Gly Arg Arg Arg Gly Pro Pro Arg Asn Tyr Ala Gly Glu
                 185                 190                 195

 Glu Glu Glu Glu Gly Ser Gly Ser Ser Glu Gly Phe Asp Pro Pro
                 200                 205                 210

 Ala Thr Asp Arg Gln Phe Ser Gly Ala Arg Asn Gln Leu Arg Arg
                 215                 220                 225

 Pro Gln Tyr Arg Pro Gln Tyr Arg Gln Arg Arg Phe Pro Pro Tyr
                 230                 235                 240

 His Val Gly Gln Thr Phe Asp Arg Arg Ser Arg Val Leu Pro His
                 245                 250                 255

 Pro Asn Arg Ile Gln Ala Gly Glu Ile Gly Glu Met Lys Asp Gly
                 260                 265                 270

 Val Pro Glu Gly Ala Gln Leu Gln Gly Pro Val His Arg Asn Pro
                 275                 280                 285

 Thr Tyr Arg Pro Arg Tyr Arg Ser Arg Gly Pro Pro Arg Pro Arg
                 290                 295                 300

 Pro Ala Pro Ala Val Gly Glu Ala Glu Asp Lys Glu Asn Gln Gln
                 305                 310                 315

 Ala Thr Ser Gly Pro Asn Gln Pro Ser Val Arg Arg Gly Tyr Arg
                 320                 325                 330

 Arg Pro Tyr Asn Tyr Arg Arg Arg Pro Arg Pro Pro Asn Ala Pro
                 335                 340                 345

 Ser Gln Asp Gly Lys Glu Ala Lys Ala Gly Glu Ala Pro Thr Glu
                 350                 355                 360

 Asn Pro Ala Pro Pro Thr Gln Gln Ser Ser Ala Glu
                 365                 370

<210> 225
<211> 2922
<212> DNA
<213> Homo sapien

<400> 225
 ggacaccggg ccatgcacgc ccccaactga agctgcatct caaagccgaa 50

 gattccagca gcccagggga tttcaaagag ctcagactca gaggaacatc 100

 tgcggagaga cccccgaagc cctctccagg gcagtcctca tccagacgct 150

 ccgctagtgc agacaggagc gcgcagtggc cccggctcgc cgcgccatgg 200

 agcggatccc cagcgcgcaa ccaccccccg cctgcctgcc caaagcaccg 250

 ggactggagc acggagacct accagggatg taccctgccc acatgtacca 300

 agtgtacaag tcaagacggg gaataaagcg gagcgaggac agcaaggaga 350

 cctacaaatt gccgcaccgg ctcatcgaga aaaagagacg tgaccggatt 400

 aacgagtgca tcgcccagct gaaggatctc ctacccgaac atctcaaact 450

 tacaactttg ggtcacttgg aaaaagcagt ggttcttgaa cttaccttga 500

 agcatgtgaa agcactaaca aacctaattg atcagcagca gcagaaaatc 550

 attgccctgc agagtggttt acaagctggt gagctgtcag ggagaaatgt 600

 cgaaacaggt caagagatgt tctgctcagg tttccagaca tgtgcccggg 650

 aggtgcttca gtatctggcc aagcacgaga acactcggga cctgaagtct 700

 tcgcagcttg tcacccacct ccaccgggtg gtctcggagc tgctgcaggg 750

 tggtacctcc aggaagccat cagacccagc tcccaaagtg atggacttca 800

 aggaaaaacc cagctctccg gccaaaggtt cggaaggtcc tgggaaaaac 850

 tgcgtgccag tcatccagcg gactttcgct cactcgagtg gggagcagag 900

 cggcagcgac acggacacag acagtggcta tggaggagaa tcggagaagg 950

 gcgacttgcg cagtgagcag ccgtgcttca aaagtgacca cggacgcagg 1000

 ttcacgatgg gagaaaggat cggcgcaatt aagcaagagt ccgaagaacc 1050

 ccccacaaaa aagaaccgga tgcagctttc ggatgatgaa ggccatttca 1100

 ctagcagtga cctgatcagc tccccgttcc tgggcccaca cccacaccag 1150

 cctcctttct gcctgccctt ctacctgatc ccaccttcag cgactgccta 1200

 cctgcccatg ctggagaagt gctggtatcc cacctcagtg ccagtgctat 1250

 acccaggcct caacgcctct gccgcagccc tctctagctt catgaaccca 1300

 gacaagatct cggctccctt gctcatgccc cagagactcc cttctccctt 1350

 gccagctcat ccgtccgtcg actcttctgt cttgctccaa gctctgaagc 1400

 caatcccccc tttaaactta gaaaccaaag actaaactct ctaggggatc 1450

 ctgctgcttt gctttccttc ctcgctactt cctaaaaagc aacaaaaaag 1500

 tttttgtgaa tgctgcaaga ttgttgcatt gtgtatactg agataatctg 1550

 aggcatggag agcagattca gggtgtgtgt gtgtgtgtgt gtgtgtgtgt 1600

 gtatgtgcgt gtgcgtgcac atgtgtgcct gcgtgttggt ataggacttt 1650

 aaagctcctt ttggcatagg gaagtcacga aggattgctt gacatcagga 1700

 gacttggggg ggattgtagc agacgtctgg gcttttcccc acccagagaa 1750

 tagccccctt cgatacacat cagctggatt ttcaaaagct tcaaagtctt 1800

 ggtctgtgag tcactcttca gtttgggagc tgggtctgtg gctttgatca 1850

 gaaggtactt tcaaaagagg gctttccagg gctcagctcc caaccagctg 1900

 ttaggacccc acccttttgc ctttattgtc gacgtgactc accagacgtc 1950

 ggggagagag agcagtcaga ccgagctttc tgctaacatg gggaggtagc 2000

 aggcactggc atagcacggt agtggtttgg ggaggtttcc gcaggtctgc 2050

 tccccacccc tgcctcggaa gaataaagag aatgtagttc cctactcagg 2100

 ctttcgtagt gattagctta ctaaggaact gaaaatgggc cccttgtaca 2150

 agctgagctg ccccggaggg agggaggagt tccctgggct tctggcacct 2200

 gtttctaggc ctaaccatta gtacttactg tgcagggaac caaaccaagg 2250

 tctgagaaat gcggacaccc cgagcgagca ccccaaagtg cacaaagctg 2300

 agtaaaaagc tgcccccttc aaacagaact agactcagtt ttcaattcca 2350

 tcctaaaact ccttttaacc aagcttagct tctcaaaggc ctaaccaagc 2400

 cttggcaccg ccagatcctt tctgtaggct aattcctctt gcccaacggc 2450

 atatggagtg tccttattgc taaaaaggat tccgtctcct tcaaagaagt 2500

 tttatttttg gtccagagta cttgttttcc cgatgtgtcc agccagctcc 2550

 gcagcagctt ttcaagatgc actatgcctg attgctgatc gtgttttaac 2600

 tttttctttt cctgttttta ttttggtatt aagtcgttgc ctttatttgt 2650

 aaagctgtta taaatatata ttatataaat atattaaaaa ggaaaatgtt 2700

 tcagatgttt atttgtataa ttacttgatt cacacagtga gaaaaaatga 2750

 atgtattcct gtttttgaag agaagaataa tttttttttc tctagggaga 2800

 ggtacagtgt ttatattttg gagccttcct gaaggtgtaa aattgtaaat 2850

 atttttatct atgagtaaat gttaagtagt tgttttaaaa tacttaataa 2900

 aataattctt ttcctgtgga ag 2922

<210> 226
<211> 412
<212> PRT
<213> Homo sapien

<400> 226
 Met Glu Arg Ile Pro Ser Ala Gln Pro Pro Pro Ala Cys Leu Pro
   1               5                  10                  15

 Lys Ala Pro Gly Leu Glu His Gly Asp Leu Pro Gly Met Tyr Pro
                  20                  25                  30

 Ala His Met Tyr Gln Val Tyr Lys Ser Arg Arg Gly Ile Lys Arg
                  35                  40                  45

 Ser Glu Asp Ser Lys Glu Thr Tyr Lys Leu Pro His Arg Leu Ile
                  50                  55                  60

 Glu Lys Lys Arg Arg Asp Arg Ile Asn Glu Cys Ile Ala Gln Leu
                  65                  70                  75

 Lys Asp Leu Leu Pro Glu His Leu Lys Leu Thr Thr Leu Gly His
                  80                  85                  90

 Leu Glu Lys Ala Val Val Leu Glu Leu Thr Leu Lys His Val Lys
                  95                 100                 105

 Ala Leu Thr Asn Leu Ile Asp Gln Gln Gln Gln Lys Ile Ile Ala
                 110                 115                 120

 Leu Gln Ser Gly Leu Gln Ala Gly Glu Leu Ser Gly Arg Asn Val
                 125                 130                 135

 Glu Thr Gly Gln Glu Met Phe Cys Ser Gly Phe Gln Thr Cys Ala
                 140                 145                 150

 Arg Glu Val Leu Gln Tyr Leu Ala Lys His Glu Asn Thr Arg Asp
                 155                 160                 165

 Leu Lys Ser Ser Gln Leu Val Thr His Leu His Arg Val Val Ser
                 170                 175                 180

 Glu Leu Leu Gln Gly Gly Thr Ser Arg Lys Pro Ser Asp Pro Ala
                 185                 190                 195

 Pro Lys Val Met Asp Phe Lys Glu Lys Pro Ser Ser Pro Ala Lys
                 200                 205                 210

 Gly Ser Glu Gly Pro Gly Lys Asn Cys Val Pro Val Ile Gln Arg
                 215                 220                 225

 Thr Phe Ala His Ser Ser Gly Glu Gln Ser Gly Ser Asp Thr Asp
                 230                 235                 240

 Thr Asp Ser Gly Tyr Gly Gly Glu Ser Glu Lys Gly Asp Leu Arg
                 245                 250                 255

 Ser Glu Gln Pro Cys Phe Lys Ser Asp His Gly Arg Arg Phe Thr
                 260                 265                 270

 Met Gly Glu Arg Ile Gly Ala Ile Lys Gln Glu Ser Glu Glu Pro
                 275                 280                 285

 Pro Thr Lys Lys Asn Arg Met Gln Leu Ser Asp Asp Glu Gly His
                 290                 295                 300

 Phe Thr Ser Ser Asp Leu Ile Ser Ser Pro Phe Leu Gly Pro His
                 305                 310                 315

 Pro His Gln Pro Pro Phe Cys Leu Pro Phe Tyr Leu Ile Pro Pro
                 320                 325                 330

 Ser Ala Thr Ala Tyr Leu Pro Met Leu Glu Lys Cys Trp Tyr Pro
                 335                 340                 345

 Thr Ser Val Pro Val Leu Tyr Pro Gly Leu Asn Ala Ser Ala Ala
                 350                 355                 360

 Ala Leu Ser Ser Phe Met Asn Pro Asp Lys Ile Ser Ala Pro Leu
                 365                 370                 375

 Leu Met Pro Gln Arg Leu Pro Ser Pro Leu Pro Ala His Pro Ser
                 380                 385                 390

 Val Asp Ser Ser Val Leu Leu Gln Ala Leu Lys Pro Ile Pro Pro
                 395                 400                 405

 Leu Asn Leu Glu Thr Lys Asp
                 410

<210> 227
<211> 2922
<212> DNA
<213> Homo sapien

<400> 227
 ggacaccggg ccatgcacgc ccccaactga agctgcatct caaagccgaa 50

 gattccagca gcccagggga tttcaaagag ctcagactca gaggaacatc 100

 tgcggagaga cccccgaagc cctctccagg gcagtcctca tccagacgct 150

 ccgctagtgc agacaggagc gcgcagtggc cccggctcgc cgcgccatgg 200

 agcggatccc cagcgcgcaa ccaccccccg cctgcctgcc caaagcaccg 250

 ggactggagc acggagacct accagggatg taccctgccc acatgtacca 300

 agtgtacaag tcaagacggg gaataaagcg gagcgaggac agcaaggaga 350

 cctacaaatt gccgcaccgg ctcatcgaga aaaagagacg tgaccggatt 400

 aacgagtgca tcgcccagct gaaggatctc ctacccgaac atctcaaact 450

 tacaactttg ggtcacttgg aaaaagcagt ggttcttgaa cttaccttga 500

 agcatgtgaa agcactaaca aacctaattg atcagcagca gcagaaaatc 550

 attgccctgc agagtggttt acaagctggt gagctgtcag ggagaaatgt 600

 cgaaacaggt caagagatgt tctgctcagg tttccagaca tgtgcccggg 650

 aggtgcttca gtatctggcc aagcacgaga acactcggga cctgaagtct 700

 tcgcagcttg tcacccacct ccaccgggtg gtctcggagc tgctgcaggg 750

 tggtacctcc aggaagccat cagacccagc tcccaaagtg atggacttca 800

 aggaaaaacc cagctctccg gccaaaggtt cggaaggtcc tgggaaaaac 850

 tgcgtgccag tcatccagcg gactttcgct cactcgagtg gggagcagag 900

 cggcagcgac acggacacag acagtggcta tggaggagaa tcggagaagg 950

 gcgacttgcg cagtgagcag ccgtgcttca aaagtgacca cggacgcagg 1000

 ttcacgatgg gagaaaggat cggcgcaatt aagcaagagt ccgaagaacc 1050

 ccccacaaaa aagaaccgga tgcagctttc ggatgatgaa ggccatttca 1100

 ctagcagtga cctgatcagc tccccgttcc tgggcccaca cccacaccag 1150

 cctcctttct gcctgccctt ctacctgatc ccaccttcag cgactgccta 1200

 cctgcccatg ctggagaagt gctggtatcc cacctcagtg ccagtgctat 1250

 acccaggcct caacgcctct gccgcagccc tctctagctt catgaaccca 1300

 gacaagatct cggctccctt gctcatgccc cagagactcc cttctccctt 1350

 gccagctcat ccgtccgtcg actcttctgt cttgctccaa gctctgaagc 1400

 caatcccccc tttaaactta gaaaccaaag actaaactct ctaggggatc 1450

 ctgctgcttt gctttccttc ctcgctactt cctaaaaagc aacaaaaaag 1500

 tttttgtgaa tgctgcaaga ttgttgcatt gtgtatactg agataatctg 1550

 aggcatggag agcagattca gggtgtgtgt gtgtgtgtgt gtgtgtgtgt 1600

 gtatgtgcgt gtgcgtgcac atgtgtgcct gcgtgttggt ataggacttt 1650

 aaagctcctt ttggcatagg gaagtcacga aggattgctt gacatcagga 1700

 gacttggggg ggattgtagc agacgtctgg gcttttcccc acccagagaa 1750

 tagccccctt cgatacacat cagctggatt ttcaaaagct tcaaagtctt 1800

 ggtctgtgag tcactcttca gtttgggagc tgggtctgtg gctttgatca 1850

 gaaggtactt tcaaaagagg gctttccagg gctcagctcc caaccagctg 1900

 ttaggacccc acccttttgc ctttattgtc gacgtgactc accagacgtc 1950

 ggggagagag agcagtcaga ccgagctttc tgctaacatg gggaggtagc 2000

 aggcactggc atagcacggt agtggtttgg ggaggtttcc gcaggtctgc 2050

 tccccacccc tgcctcggaa gaataaagag aatgtagttc cctactcagg 2100

 ctttcgtagt gattagctta ctaaggaact gaaaatgggc cccttgtaca 2150

 agctgagctg ccccggaggg agggaggagt tccctgggct tctggcacct 2200

 gtttctaggc ctaaccatta gtacttactg tgcagggaac caaaccaagg 2250

 tctgagaaat gcggacaccc cgagcgagca ccccaaagtg cacaaagctg 2300

 agtaaaaagc tgcccccttc aaacagaact agactcagtt ttcaattcca 2350

 tcctaaaact ccttttaacc aagcttagct tctcaaaggc ctaaccaagc 2400

 cttggcaccg ccagatcctt tctgtaggct aattcctctt gcccaacggc 2450

 atatggagtg tccttattgc taaaaaggat tccgtctcct tcaaagaagt 2500

 tttatttttg gtccagagta cttgttttcc cgatgtgtcc agccagctcc 2550

 gcagcagctt ttcaagatgc actatgcctg attgctgatc gtgttttaac 2600

 tttttctttt cctgttttta ttttggtatt aagtcgttgc ctttatttgt 2650

 aaagctgtta taaatatata ttatataaat atattaaaaa ggaaaatgtt 2700

 tcagatgttt atttgtataa ttacttgatt cacacagtga gaaaaaatga 2750

 atgtattcct gtttttgaag agaagaataa tttttttttc tctagggaga 2800

 ggtacagtgt ttatattttg gagccttcct gaaggtgtaa aattgtaaat 2850

 atttttatct atgagtaaat gttaagtagt tgttttaaaa tacttaataa 2900

 aataattctt ttcctgtgga ag 2922

<210> 228
<211> 412
<212> PRT
<213> Homo sapien

<400> 228
 Met Glu Arg Ile Pro Ser Ala Gln Pro Pro Pro Ala Cys Leu Pro
   1               5                  10                  15

 Lys Ala Pro Gly Leu Glu His Gly Asp Leu Pro Gly Met Tyr Pro
                  20                  25                  30

 Ala His Met Tyr Gln Val Tyr Lys Ser Arg Arg Gly Ile Lys Arg
                  35                  40                  45

 Ser Glu Asp Ser Lys Glu Thr Tyr Lys Leu Pro His Arg Leu Ile
                  50                  55                  60

 Glu Lys Lys Arg Arg Asp Arg Ile Asn Glu Cys Ile Ala Gln Leu
                  65                  70                  75

 Lys Asp Leu Leu Pro Glu His Leu Lys Leu Thr Thr Leu Gly His
                  80                  85                  90

 Leu Glu Lys Ala Val Val Leu Glu Leu Thr Leu Lys His Val Lys
                  95                 100                 105

 Ala Leu Thr Asn Leu Ile Asp Gln Gln Gln Gln Lys Ile Ile Ala
                 110                 115                 120

 Leu Gln Ser Gly Leu Gln Ala Gly Glu Leu Ser Gly Arg Asn Val
                 125                 130                 135

 Glu Thr Gly Gln Glu Met Phe Cys Ser Gly Phe Gln Thr Cys Ala
                 140                 145                 150

 Arg Glu Val Leu Gln Tyr Leu Ala Lys His Glu Asn Thr Arg Asp
                 155                 160                 165

 Leu Lys Ser Ser Gln Leu Val Thr His Leu His Arg Val Val Ser
                 170                 175                 180

 Glu Leu Leu Gln Gly Gly Thr Ser Arg Lys Pro Ser Asp Pro Ala
                 185                 190                 195

 Pro Lys Val Met Asp Phe Lys Glu Lys Pro Ser Ser Pro Ala Lys
                 200                 205                 210

 Gly Ser Glu Gly Pro Gly Lys Asn Cys Val Pro Val Ile Gln Arg
                 215                 220                 225

 Thr Phe Ala His Ser Ser Gly Glu Gln Ser Gly Ser Asp Thr Asp
                 230                 235                 240

 Thr Asp Ser Gly Tyr Gly Gly Glu Ser Glu Lys Gly Asp Leu Arg
                 245                 250                 255

 Ser Glu Gln Pro Cys Phe Lys Ser Asp His Gly Arg Arg Phe Thr
                 260                 265                 270

 Met Gly Glu Arg Ile Gly Ala Ile Lys Gln Glu Ser Glu Glu Pro
                 275                 280                 285

 Pro Thr Lys Lys Asn Arg Met Gln Leu Ser Asp Asp Glu Gly His
                 290                 295                 300

 Phe Thr Ser Ser Asp Leu Ile Ser Ser Pro Phe Leu Gly Pro His
                 305                 310                 315

 Pro His Gln Pro Pro Phe Cys Leu Pro Phe Tyr Leu Ile Pro Pro
                 320                 325                 330

 Ser Ala Thr Ala Tyr Leu Pro Met Leu Glu Lys Cys Trp Tyr Pro
                 335                 340                 345

 Thr Ser Val Pro Val Leu Tyr Pro Gly Leu Asn Ala Ser Ala Ala
                 350                 355                 360

 Ala Leu Ser Ser Phe Met Asn Pro Asp Lys Ile Ser Ala Pro Leu
                 365                 370                 375

 Leu Met Pro Gln Arg Leu Pro Ser Pro Leu Pro Ala His Pro Ser
                 380                 385                 390

 Val Asp Ser Ser Val Leu Leu Gln Ala Leu Lys Pro Ile Pro Pro
                 395                 400                 405

 Leu Asn Leu Glu Thr Lys Asp
                 410

<210> 229
<211> 849
<212> DNA
<213> Homo sapien

<400> 229
 gcggtcagct attgacactt cctggtggga tccgagtgag gcgacggggt 50

 aggggttggc gctcaggcgg cgaccatggc gtatcacggc ctcactgtgc 100

 ctctcattgt gatgagcgtg ttctggggct tcgtcggctt cttggtgcct 150

 tggttcatcc ctaagggtcc taaccgggga gttatcatta ccatgttggt 200

 gacctgttca gtttgctgct atctcttttg gctgattgca attctggccc 250

 aactcaaccc tctctttgga ccgcaattga aaaatgaaac catctggtat 300

 ctgaagtatc attggccttg aggaagaaga catgctctac agtgctcagt 350

 ctttgaggtc acgagaagag aatgccttct agatgcaaaa tcacctccaa 400

 accagaccac ttttcttgac ttgcctgttt tggccattag ctgccttaaa 450

 cgttaacagc acatttgaat gccttattct acaatgcagc gtgttttcct 500

 ttgccttttt tgcactttgg tgaattacgt gcctccataa cctgaactgt 550

 gccgactcca caaaacgatt atgtactctt ctgagataga agatgctgtt 600

 cttctgagag atacgttact ctctccttgg aatctgtgga tttgaagatg 650

 gctcctgcct tctcacgtgg gaatcagtga agtgtttaga aactgctgca 700

 agacaaacaa gactccagtg gggtggtcag taggagagca cgttcagagg 750

 gaagagccat ctcaacagaa tcgcaccaaa ctatactttc aggatgaatt 800

 tcttctttct gccatctttt ggaataaata ttttcctcct ttctatgga 849

<210> 230
<211> 81
<212> PRT
<213> Homo sapien

<400> 230
 Met Ala Tyr His Gly Leu Thr Val Pro Leu Ile Val Met Ser Val
   1               5                  10                  15

 Phe Trp Gly Phe Val Gly Phe Leu Val Pro Trp Phe Ile Pro Lys
                  20                  25                  30

 Gly Pro Asn Arg Gly Val Ile Ile Thr Met Leu Val Thr Cys Ser
                  35                  40                  45

 Val Cys Cys Tyr Leu Phe Trp Leu Ile Ala Ile Leu Ala Gln Leu
                  50                  55                  60

 Asn Pro Leu Phe Gly Pro Gln Leu Lys Asn Glu Thr Ile Trp Tyr
                  65                  70                  75

 Leu Lys Tyr His Trp Pro
                  80

<210> 231
<211> 1333
<212> DNA
<213> Homo sapien

<400> 231
 tagagtcgtt gggcccggcg cgacccgcag gagcgtagag agcgcgggac 50

 tagagtgcag agctccggga cgtggatcgg agccggcgcg atgggcggag 100

 agcaggagga ggagcggttc gacggcatgt tgctggccat ggctcagcag 150

 cacgagggcg gcgtgcagga gcttgtgaac accttcttca gcttccttcg 200

 acgcaaaaca gactttttca ttggaggaga agaagggatg gcagagaagc 250

 ttatcacaca gactttcagc caccacaatc agctggcaca gaagacccgg 300

 cgggagaaga gagcccggca ggaggccgag cggcgggaga aggcggagcg 350

 ggcggccaga ctggccaagg aagccaagtc agagacctca gggccccaga 400

 tcaaggagct aactgatgaa gaggcagaga ggctgcagct agagattgac 450

 cagaaaaagg atgcagagaa tcatgaggcc cagctcaaga acggcagcct 500

 tgactcccca gggaagcagg atactgagga agatgaggag gaagatgaga 550

 aggacaaagg aaaactgaag cccaacctag gcaacggggc agacctgccc 600

 aattaccgct ggacccagac cctgtcggag ctggacctgg cggtcccttt 650

 ctgtgtgaac ttccggctga aagggaagga catggtggtg gacatccagc 700

 ggcggcacct ccgggtgggg ctcaaggggc agccagcgat cattgatggg 750

 gagctctaca atgaagtgaa ggtggaggag agctcgtggc tcattgagga 800

 cggcaaggtg gtgactgtgc atctggagaa gatcaataag atggagtggt 850

 ggagccgctt ggtgtccagt gaccctgaga tcaacaccaa gaagattaac 900

 cctgagaatt ccaagctgtc agacctggac agtgagactc gcagcatggt 950

 ggaaaagatg atgtatgacc agcgacagaa gtccatgggg ctgccaactt 1000

 cagacgaaca gaagaaacag gagattctga agaagttcat ggatcaacat 1050

 ccggagatgg atttttccaa ggctaaattc aactagcccc tgttttttcc 1100

 tccctgaact cttggggctg agctgcaacc acccaacttt ctttcccact 1150

 cttctctggg acttgtgggc ctcagggctt ggggcaggca tgggactggc 1200

 ccaggcacac aggtcccggg gcatcaggag aaaggctggg tcttgggacc 1250

 ttgtcctccc cagttggcct actgttacac attaaaacga tttgcccagc 1300

 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1333

<210> 232
<211> 331
<212> PRT
<213> Homo sapien

<400> 232
 Met Gly Gly Glu Gln Glu Glu Glu Arg Phe Asp Gly Met Leu Leu
   1               5                  10                  15

 Ala Met Ala Gln Gln His Glu Gly Gly Val Gln Glu Leu Val Asn
                  20                  25                  30

 Thr Phe Phe Ser Phe Leu Arg Arg Lys Thr Asp Phe Phe Ile Gly
                  35                  40                  45

 Gly Glu Glu Gly Met Ala Glu Lys Leu Ile Thr Gln Thr Phe Ser
                  50                  55                  60

 His His Asn Gln Leu Ala Gln Lys Thr Arg Arg Glu Lys Arg Ala
                  65                  70                  75

 Arg Gln Glu Ala Glu Arg Arg Glu Lys Ala Glu Arg Ala Ala Arg
                  80                  85                  90

 Leu Ala Lys Glu Ala Lys Ser Glu Thr Ser Gly Pro Gln Ile Lys
                  95                 100                 105

 Glu Leu Thr Asp Glu Glu Ala Glu Arg Leu Gln Leu Glu Ile Asp
                 110                 115                 120

 Gln Lys Lys Asp Ala Glu Asn His Glu Ala Gln Leu Lys Asn Gly
                 125                 130                 135

 Ser Leu Asp Ser Pro Gly Lys Gln Asp Thr Glu Glu Asp Glu Glu
                 140                 145                 150

 Glu Asp Glu Lys Asp Lys Gly Lys Leu Lys Pro Asn Leu Gly Asn
                 155                 160                 165

 Gly Ala Asp Leu Pro Asn Tyr Arg Trp Thr Gln Thr Leu Ser Glu
                 170                 175                 180

 Leu Asp Leu Ala Val Pro Phe Cys Val Asn Phe Arg Leu Lys Gly
                 185                 190                 195

 Lys Asp Met Val Val Asp Ile Gln Arg Arg His Leu Arg Val Gly
                 200                 205                 210

 Leu Lys Gly Gln Pro Ala Ile Ile Asp Gly Glu Leu Tyr Asn Glu
                 215                 220                 225

 Val Lys Val Glu Glu Ser Ser Trp Leu Ile Glu Asp Gly Lys Val
                 230                 235                 240

 Val Thr Val His Leu Glu Lys Ile Asn Lys Met Glu Trp Trp Ser
                 245                 250                 255

 Arg Leu Val Ser Ser Asp Pro Glu Ile Asn Thr Lys Lys Ile Asn
                 260                 265                 270

 Pro Glu Asn Ser Lys Leu Ser Asp Leu Asp Ser Glu Thr Arg Ser
                 275                 280                 285

 Met Val Glu Lys Met Met Tyr Asp Gln Arg Gln Lys Ser Met Gly
                 290                 295                 300

 Leu Pro Thr Ser Asp Glu Gln Lys Lys Gln Glu Ile Leu Lys Lys
                 305                 310                 315

 Phe Met Asp Gln His Pro Glu Met Asp Phe Ser Lys Ala Lys Phe
                 320                 325                 330

 Asn


<210> 233
<211> 4539
<212> DNA
<213> Homo sapien

<400> 233
 cggcgcgcac actgctcgct gggccgcggc tcccgggtgt cccaggcccg 50

 gccggtgcgc agagcatggc gggtgcgggc ccgaagcggc gcgcgctagc 100

 ggcgccggcg gccgaggaga aggaagaggc gcgggagaag atgctggccg 150

 ccaagagcgc ggacggctcg gcgccggcag gcgagggcga gggcgtgacc 200

 ctgcagcgga acatcacgct gctcaacggc gtggccatca tcgtggggac 250

 cattatcggc tcgggcatct tcgtgacgcc cacgggcgtg ctcaaggagg 300

 caggctcgcc ggggctggcg ctggtggtgt gggccgcgtg cggcgtcttc 350

 tccatcgtgg gcgcgctctg ctacgcggag ctcggcacca ccatctccaa 400

 atcgggcggc gactacgcct acatgctgga ggtctacggc tcgctgcccg 450

 ccttcctcaa gctctggatc gagctgctca tcatccggcc ttcatcgcag 500

 tacatcgtgg ccctggtctt cgccacctac ctgctcaagc cgctcttccc 550

 cacctgcccg gtgcccgagg aggcagccaa gctcgtggcc tgcctctgcg 600

 tgctgctgct cacggccgtg aactgctaca gcgtgaaggc cgccacccgg 650

 gtccaggatg cctttgccgc cgccaagctc ctggccctgg ccctgatcat 700

 cctgctgggc ttcgtccaga tcgggaaggg tgatgtgtcc aatctagatc 750

 ccaacttctc atttgaaggc accaaactgg atgtggggaa cattgtgctg 800

 gcattataca gcggcctctt tgcctatgga ggatggaatt acttgaattt 850

 cgtcacagag gaaatgatca acccctacag aaacctgccc ctggccatca 900

 tcatctccct gcccatcgtg acgctggtgt acgtgctgac caacctggcc 950

 tacttcacca ccctgtccac cgagcagatg ctgtcgtccg aggccgtggc 1000

 cgtggacttc gggaactatc acctgggcgt catgtcctgg atcatccccg 1050

 tcttcgtggg cctgtcctgc ttcggctccg tcaatgggtc cctgttcaca 1100

 tcctccaggc tcttcttcgt ggggtcccgg gaaggccacc tgccctccat 1150

 cctctccatg atccacccac agctcctcac ccccgtgccg tccctcgtgt 1200

 tcacgtgtgt gatgacgctg ctctacgcct tctccaagga catcttctcc 1250

 gtcatcaact tcttcagctt cttcaactgg ctctgcgtgg ccctggccat 1300

 catcggcatg atctggctgc gccacagaaa gcctgagctt gagcggccca 1350

 tcaaggtgaa cctggccctg cctgtgttct tcatcctggc ctgcctcttc 1400

 ctgatcgccg tctccttctg gaagacaccc gtggagtgtg gcatcggctt 1450

 caccatcatc ctcagcgggc tgcccgtcta cttcttcggg gtctggtgga 1500

 aaaacaagcc caagtggctc ctccagggca tcttctccac gaccgtcctg 1550

 tgtcagaagc tcatgcaggt ggtcccccag gagacatagc caggaggccg 1600

 agtggctgcc ggaggagcat gcgcagaggc cagttaaagt agatcacctc 1650

 ctcgaaccca ctccggttcc ccgcaaccca cagctcagct gcccatccca 1700

 gtccctcgcc gtccctccca ggtcgggcag tggaggctgc tgtgaaaact 1750

 ctggtacgaa tctcatccct caactgaggg ccagggaccc aggtgtgcct 1800

 gtgctcctgc ccaggagcag cttttggtct ccttgggccc tttttccctt 1850

 ccctcctttg tttacttata tatatatttt ttttaaactt aaattttggg 1900

 tcaacttgac accactaaga tgatttttta aggagctggg ggaaggcagg 1950

 agccttcctt tctcctgccc caagggccca gaccctgggc aaacagagct 2000

 actgagactt ggaacctcat tgctacgaca gacttgcact gaagccggac 2050

 agctgcccag acacatgggc ttgtgacatt cgtgaaaacc aaccctgtgg 2100

 gcttatgtct ctgccttagg gtttgcagag tggaaactca gccgtagggt 2150

 ggcactggga gggggtgggg gatctgggca aggtgggtga ttcctcccag 2200

 gaggtgcttg aggccccgat ggactcctga ccataatcct agccccgaga 2250

 caccatcctg agccagggaa cagccccagg gttggggggt gccggcatct 2300

 cccctagctc accaggcctg gcctctgggc agtgtggcct cttggctatt 2350

 tctgttccag ttttggaggc tgagttctgg ttcatgcaga caaagccctg 2400

 tccttcagtc ttctagaaac agagacaaga aaggcagaca caccgcggcc 2450

 aggcacccat gtgggcgccc accctgggct ccacacagca gtgtcccctg 2500

 ccccagaggt cgcagctacc ctcagcctcc aatgcattgg cctctgtacc 2550

 gcccggcagc cccttctggc cggtgctggg ttcccactcc cggcctaggc 2600

 acctccccgc tctccctgtc acgctcatgt cctgtcctgg tcctgatgcc 2650

 cgttgtctag gagacagagc caagcactgc tcacgtctct gccgcctgcg 2700

 tttggaggcc cctgggctct cacccagtcc ccacccgcct gcagagaggg 2750

 aactagggca ccccttgttt ctgttgttcc cgtgaatttt tttcgctatg 2800

 ggaggcagcc gaggcctggc caatgcggcc cactttcctg agctgtcgct 2850

 gcctccatgg cagcagccaa ggacccccag aacaagaaga cccccccgca 2900

 ggatccctcc tgagctcggg gggctctgcc ttctcaggcc ccgggcttcc 2950

 cttctcccca gccagaggtg gagccaagtg gtccagcgtc actccagtgc 3000

 tcagctgtgg ctggaggagc tggcctgtgg cacagccctg agtgtcccaa 3050

 gccgggagcc aacgaagccg gacacggctt cactgaccag cggctgctca 3100

 agccgcaagc tctcagcaag tgcccagtgg agcctgccgc ccccacctgg 3150

 gcaccgggac cccctcacca tccagtgggc ccggagaaac ctgatgaaca 3200

 gtttggggac tcaggaccag atgtccgtct ctcttgcttg aggaatgaag 3250

 acctttattc acccctgccc cgttgcttcc cgctgcacat ggacagactt 3300

 cacagcgtct gctcatagga cctgcatcct tcctggggac gaattccact 3350

 cgtccaaggg acagcccacg gtctggaggc cgaggaccac cagcaggcag 3400

 gtggactgac tgtgttgggc aagacctctt ccctctgggc ctgttctctt 3450

 ggctgcaaat aaggacagca gctggtgccc cacctgcctg gtgcattgct 3500

 gtgtgaatcc aggaggcagt ggacatcgta ggcagccacg gccccgggtc 3550

 caggagaagt gctccctgga ggcacgcacc actgcttccc actggggccg 3600

 gcggggccca cgcacgacgt cagcctctta ccttcccgcc tcggctaggg 3650

 gtcctcggga tgccgttctg ttccaacctc ctgctctggg aggtggacat 3700

 gcctcaagga tacagggagc cggcggcctc tcgacggcac gcacttgcct 3750

 gttggctgct gcggctgtgg gcgagcatgg gggctgccag cgtctgttgt 3800

 ggaaagtagc tgctagtgaa atggctgggg ccgctggggt ccgtcttcac 3850

 actgcgcagg tctcttctgg gcgtctgagc tggggtggga gctcctccgc 3900

 agaaggttgg tggggggtcc agtctgtgat ccttggtgct gtgtgcccca 3950

 ctccagcctg gggaccccac ttcagaaggt aggggccgtg tcccgcggtg 4000

 ctgactgagg cctgcttccc cctccccctc ctgctgtgct ggaattccac 4050

 agggaccagg gccaccgcag gggactgtct cagaagactt gatttttccg 4100

 tccctttttc tccacactcc actgacaaac gtccccagcg gtttccactt 4150

 gtgggcttca ggtgttttca agcacaaccc accacaacaa gcaagtgcat 4200

 tttcagtcgt tgtgcttttt tgttttgtgc taacgtctta ctaatttaaa 4250

 gatgctgtcg gcaccatgtt tatttatttc cagtggtcat gctcagcctt 4300

 gctgctctgc gtggcgcagg tgccatgcct gctccctgtc tgtgtcccag 4350

 ccacgcaggg ccatccactg tgacgtcggc cgaccaggct ggacaccctc 4400

 tgccgagtaa tgacgtgtgt ggctgggacc ttctttattc tgtgttaatg 4450

 gctaacctgt tacactgggc tgggttgggt agggtgttct ggcttttttg 4500

 tggggttttt atttttaaag aaacactcaa tcatcctag 4539

<210> 234
<211> 507
<212> PRT
<213> Homo sapien

<400> 234
 Met Ala Gly Ala Gly Pro Lys Arg Arg Ala Leu Ala Ala Pro Ala
   1               5                  10                  15

 Ala Glu Glu Lys Glu Glu Ala Arg Glu Lys Met Leu Ala Ala Lys
                  20                  25                  30

 Ser Ala Asp Gly Ser Ala Pro Ala Gly Glu Gly Glu Gly Val Thr
                  35                  40                  45

 Leu Gln Arg Asn Ile Thr Leu Leu Asn Gly Val Ala Ile Ile Val
                  50                  55                  60

 Gly Thr Ile Ile Gly Ser Gly Ile Phe Val Thr Pro Thr Gly Val
                  65                  70                  75

 Leu Lys Glu Ala Gly Ser Pro Gly Leu Ala Leu Val Val Trp Ala
                  80                  85                  90

 Ala Cys Gly Val Phe Ser Ile Val Gly Ala Leu Cys Tyr Ala Glu
                  95                 100                 105

 Leu Gly Thr Thr Ile Ser Lys Ser Gly Gly Asp Tyr Ala Tyr Met
                 110                 115                 120

 Leu Glu Val Tyr Gly Ser Leu Pro Ala Phe Leu Lys Leu Trp Ile
                 125                 130                 135

 Glu Leu Leu Ile Ile Arg Pro Ser Ser Gln Tyr Ile Val Ala Leu
                 140                 145                 150

 Val Phe Ala Thr Tyr Leu Leu Lys Pro Leu Phe Pro Thr Cys Pro
                 155                 160                 165

 Val Pro Glu Glu Ala Ala Lys Leu Val Ala Cys Leu Cys Val Leu
                 170                 175                 180

 Leu Leu Thr Ala Val Asn Cys Tyr Ser Val Lys Ala Ala Thr Arg
                 185                 190                 195

 Val Gln Asp Ala Phe Ala Ala Ala Lys Leu Leu Ala Leu Ala Leu
                 200                 205                 210

 Ile Ile Leu Leu Gly Phe Val Gln Ile Gly Lys Gly Asp Val Ser
                 215                 220                 225

 Asn Leu Asp Pro Asn Phe Ser Phe Glu Gly Thr Lys Leu Asp Val
                 230                 235                 240

 Gly Asn Ile Val Leu Ala Leu Tyr Ser Gly Leu Phe Ala Tyr Gly
                 245                 250                 255

 Gly Trp Asn Tyr Leu Asn Phe Val Thr Glu Glu Met Ile Asn Pro
                 260                 265                 270

 Tyr Arg Asn Leu Pro Leu Ala Ile Ile Ile Ser Leu Pro Ile Val
                 275                 280                 285

 Thr Leu Val Tyr Val Leu Thr Asn Leu Ala Tyr Phe Thr Thr Leu
                 290                 295                 300

 Ser Thr Glu Gln Met Leu Ser Ser Glu Ala Val Ala Val Asp Phe
                 305                 310                 315

 Gly Asn Tyr His Leu Gly Val Met Ser Trp Ile Ile Pro Val Phe
                 320                 325                 330

 Val Gly Leu Ser Cys Phe Gly Ser Val Asn Gly Ser Leu Phe Thr
                 335                 340                 345

 Ser Ser Arg Leu Phe Phe Val Gly Ser Arg Glu Gly His Leu Pro
                 350                 355                 360

 Ser Ile Leu Ser Met Ile His Pro Gln Leu Leu Thr Pro Val Pro
                 365                 370                 375

 Ser Leu Val Phe Thr Cys Val Met Thr Leu Leu Tyr Ala Phe Ser
                 380                 385                 390

 Lys Asp Ile Phe Ser Val Ile Asn Phe Phe Ser Phe Phe Asn Trp
                 395                 400                 405

 Leu Cys Val Ala Leu Ala Ile Ile Gly Met Ile Trp Leu Arg His
                 410                 415                 420

 Arg Lys Pro Glu Leu Glu Arg Pro Ile Lys Val Asn Leu Ala Leu
                 425                 430                 435

 Pro Val Phe Phe Ile Leu Ala Cys Leu Phe Leu Ile Ala Val Ser
                 440                 445                 450

 Phe Trp Lys Thr Pro Val Glu Cys Gly Ile Gly Phe Thr Ile Ile
                 455                 460                 465

 Leu Ser Gly Leu Pro Val Tyr Phe Phe Gly Val Trp Trp Lys Asn
                 470                 475                 480

 Lys Pro Lys Trp Leu Leu Gln Gly Ile Phe Ser Thr Thr Val Leu
                 485                 490                 495

 Cys Gln Lys Leu Met Gln Val Val Pro Gln Glu Thr
                 500                 505

<210> 235
<211> 1989
<212> DNA
<213> Homo sapien

<400> 235
 gcggccgccg ggactcttcc tggagacacc gccatggccg ggctatcccg 50

 cgggtccgcg cgcgcactgc tcgccgccct gctggcgtcg acgctgttgg 100

 cgctgctcgt gtcgcccgcg cggggtcgcg gcggccggga ccacggggac 150

 tgggacgagg cctcccggct gccgccgcta ccaccccgcg aggacgcggc 200

 gcgcgtggcc cgcttcgtga cgcacgtctc cgactggggc gctctggcca 250

 ccatctccac gctggaggcg gtgcgcggcc ggcccttcgc cgacgtcctc 300

 tcgctcagcg acgggccccc gggcgcgggc agcggcgtgc cctatttcta 350

 cctgagcccg ctgcagctct ccgtgagcaa cctgcaggag aatccatatg 400

 ctacactgac catgactttg gcacagacca acttctgcaa gaaacatgga 450

 tttgatccac aaagtcccct ttgtgttcac ataatgctgt caggaactgt 500

 gaccaaggtg aatgaaacag aaatggatat tgcaaagcat tcgttattca 550

 ttcgacaccc tgagatgaaa acctggcctt ccagccataa ttggttcttt 600

 gctaagttga atataaccaa tatctgggtc ctggactact ttggtggacc 650

 aaaaatcgtg acaccagaag aatattataa tgtcacagtt cagtgaagca 700

 gactgtggtg aatttagcaa cacttatgaa gtttcttaaa gtggctcata 750

 cacacttaaa aggcttaatg tttctctgga aagcgtccca gaatattagc 800

 cagttttctg tcacatgctg gtttgtttgc ttgcttgttt acttgcttgt 850

 ttaccaatag agttgacctg ttattggatt tcctggaaga tgtggtagct 900

 acttttttcc tattttgaag ccattttcgt agagaaatat ccttcactat 950

 aatcaaataa gttttgtccc atcaattcca aagatgtttc cagtggtgct 1000

 cttgaagagg aatgagtacc agttttaaat tgcccattgg catttgaagg 1050

 tagttgagta tgtgttcttt attcctagaa gccactgtgc ttggtagagt 1100

 gcatcactca ccacagctgc ctcctgagct gcctgagcct ggtgcaaaag 1150

 gattggcccc cattatggtg cttctgaata aatcttgcca agatagacaa 1200

 acaatgatga aactcagatg gagcttccta ctcatgttga tttatgtctc 1250

 acaatcctgg gtattgttaa ttcaacatag ggtgaaacta tttctgataa 1300

 agaacttttg aaaaactttt tatactctaa agtgatactc agaacaaaag 1350

 aaagtcataa aactcctgaa tttaatttcc ccacctaagt cgagacagta 1400

 ttatcaaaac acatgtgcac acagattatt ttttggctcc aaaactggat 1450

 tgcaaaagaa agaggagaag aatattttgt gtgttcctgg tattctttta 1500

 taagtaaagt ttacccaggc atggaccagc ttcagccagg gacaaaatcc 1550

 cctcccaaac cactctccac agctttttaa aaatacttct actcttaaca 1600

 attacctaag gcttcctcaa ctgccccaaa tctcttaata gcttctagtg 1650

 ctgctacaat ctaagtcagg tcaccagagg gaagagaaca tggcattaaa 1700

 agaatcacat cttcagaaga gaagacacta atattattac ccatatacat 1750

 gatttcagaa gatgacataa gattcctctt aaagaggaaa tgtcaggaat 1800

 caagccactg aatccttaaa gagaaaagtt gaatatgagt cattgtgtct 1850

 gaaaactgca aagtgaactt aactgagatc cagcaaacag gttctgttta 1900

 agaaaaataa tttatactaa atttagtaaa atggacttct tattcaaagc 1950

 atcaataatt aaaagaatta ttttaaaaaa aaaaaaaaa 1989

<210> 236
<211> 220
<212> PRT
<213> Homo sapien

<400> 236
 Met Ala Gly Leu Ser Arg Gly Ser Ala Arg Ala Leu Leu Ala Ala
   1               5                  10                  15

 Leu Leu Ala Ser Thr Leu Leu Ala Leu Leu Val Ser Pro Ala Arg
                  20                  25                  30

 Gly Arg Gly Gly Arg Asp His Gly Asp Trp Asp Glu Ala Ser Arg
                  35                  40                  45

 Leu Pro Pro Leu Pro Pro Arg Glu Asp Ala Ala Arg Val Ala Arg
                  50                  55                  60

 Phe Val Thr His Val Ser Asp Trp Gly Ala Leu Ala Thr Ile Ser
                  65                  70                  75

 Thr Leu Glu Ala Val Arg Gly Arg Pro Phe Ala Asp Val Leu Ser
                  80                  85                  90

 Leu Ser Asp Gly Pro Pro Gly Ala Gly Ser Gly Val Pro Tyr Phe
                  95                 100                 105

 Tyr Leu Ser Pro Leu Gln Leu Ser Val Ser Asn Leu Gln Glu Asn
                 110                 115                 120

 Pro Tyr Ala Thr Leu Thr Met Thr Leu Ala Gln Thr Asn Phe Cys
                 125                 130                 135

 Lys Lys His Gly Phe Asp Pro Gln Ser Pro Leu Cys Val His Ile
                 140                 145                 150

 Met Leu Ser Gly Thr Val Thr Lys Val Asn Glu Thr Glu Met Asp
                 155                 160                 165

 Ile Ala Lys His Ser Leu Phe Ile Arg His Pro Glu Met Lys Thr
                 170                 175                 180

 Trp Pro Ser Ser His Asn Trp Phe Phe Ala Lys Leu Asn Ile Thr
                 185                 190                 195

 Asn Ile Trp Val Leu Asp Tyr Phe Gly Gly Pro Lys Ile Val Thr
                 200                 205                 210

 Pro Glu Glu Tyr Tyr Asn Val Thr Val Gln
                 215                 220

<210> 237
<211> 1231
<212> DNA
<213> Homo sapien

<400> 237
 aggtctcagc cggtcgtcgc gacgttcgcc cgctcgctct gaggctcctg 50

 aagccgaaac tagctagact ttcctccttc ccgcctgcct gtagcggcgt 100

 tgttgccact ccgccaccat gttcgaggcg cgcctggtcc agggctccat 150

 cctcaagaag gtgttggagg cactcaagga cctcatcaac gaggcctgct 200

 gggatattag ctccagcggt gtaaacctgc agagcatgga ctcgtcccac 250

 gtctctttgg tgcagctcac cctgcggtct gagggcttcg acacctaccg 300

 ctgcgaccgc aacctggcca tgggcgtgaa cctcaccagt atgtccaaaa 350

 tactaaaatg cgccggcaat gaagatatca ttacactaag ggccgaagat 400

 aacgcggata ccttggcgct agtatttgaa gcaccaaacc aggagaaagt 450

 ttcagactat gaaatgaagt tgatggattt agatgttgaa caacttggaa 500

 ttccagaaca ggagtacagc tgtgtagtaa agatgccttc tggtgaattt 550

 gcacgtatat gccgagatct cagccatatt ggagatgctg ttgtaatttc 600

 ctgtgcaaaa gacggagtga aattttctgc aagtggagaa cttggaaatg 650

 gaaacattaa attgtcacag acaagtaatg tcgataaaga ggaggaagct 700

 gttaccatag agatgaatga accagttcaa ctaacttttg cactgaggta 750

 cctgaacttc tttacaaaag ccactccact ctcttcaacg gtgacactca 800

 gtatgtctgc agatgtaccc cttgttgtag agtataaaat tgcggatatg 850

 ggacacttaa aatactactt ggctcccaag atcgaggatg aagaaggatc 900

 ttaggcattc ttaaaattca agaaaataaa actaagctct ttgagaactg 950

 cttctaagat gccagcatat actgaagtct tttctgtcac caaatttgta 1000

 cctctaagta catatgtaga tattgttttc tgtaaataac ctattttttt 1050

 tctctattct ctccaatttg tttaaagaat aaagtccaaa gtctgatctg 1100

 gtctagttaa cctagaagta tttttgtctc ttagaaatac ttgtgatttt 1150

 tataatacaa aagggtcttg actctaaatg cagttttaag aagtgttttt 1200

 gaatttaaat aaagttactt gaatttcaaa c 1231

<210> 238
<211> 261
<212> PRT
<213> Homo sapien

<400> 238
 Met Phe Glu Ala Arg Leu Val Gln Gly Ser Ile Leu Lys Lys Val
   1               5                  10                  15

 Leu Glu Ala Leu Lys Asp Leu Ile Asn Glu Ala Cys Trp Asp Ile
                  20                  25                  30

 Ser Ser Ser Gly Val Asn Leu Gln Ser Met Asp Ser Ser His Val
                  35                  40                  45

 Ser Leu Val Gln Leu Thr Leu Arg Ser Glu Gly Phe Asp Thr Tyr
                  50                  55                  60

 Arg Cys Asp Arg Asn Leu Ala Met Gly Val Asn Leu Thr Ser Met
                  65                  70                  75

 Ser Lys Ile Leu Lys Cys Ala Gly Asn Glu Asp Ile Ile Thr Leu
                  80                  85                  90

 Arg Ala Glu Asp Asn Ala Asp Thr Leu Ala Leu Val Phe Glu Ala
                  95                 100                 105

 Pro Asn Gln Glu Lys Val Ser Asp Tyr Glu Met Lys Leu Met Asp
                 110                 115                 120

 Leu Asp Val Glu Gln Leu Gly Ile Pro Glu Gln Glu Tyr Ser Cys
                 125                 130                 135

 Val Val Lys Met Pro Ser Gly Glu Phe Ala Arg Ile Cys Arg Asp
                 140                 145                 150

 Leu Ser His Ile Gly Asp Ala Val Val Ile Ser Cys Ala Lys Asp
                 155                 160                 165

 Gly Val Lys Phe Ser Ala Ser Gly Glu Leu Gly Asn Gly Asn Ile
                 170                 175                 180

 Lys Leu Ser Gln Thr Ser Asn Val Asp Lys Glu Glu Glu Ala Val
                 185                 190                 195

 Thr Ile Glu Met Asn Glu Pro Val Gln Leu Thr Phe Ala Leu Arg
                 200                 205                 210

 Tyr Leu Asn Phe Phe Thr Lys Ala Thr Pro Leu Ser Ser Thr Val
                 215                 220                 225

 Thr Leu Ser Met Ser Ala Asp Val Pro Leu Val Val Glu Tyr Lys
                 230                 235                 240

 Ile Ala Asp Met Gly His Leu Lys Tyr Tyr Leu Ala Pro Lys Ile
                 245                 250                 255

 Glu Asp Glu Glu Gly Ser
                 260

<210> 239
<211> 3089
<212> DNA
<213> Homo sapien

<400> 239
 aaagattccg aggtgcagaa gttgtctgag tgcgttggtc ggcggcagtc 50

 gggccagacc caggactctg cgactttaca tctttaaatg gatgagatgg 100

 ctaccactca gatttccaaa gatgagcttg atgaactcaa agaggccttt 150

 gcaaaagttg atctcaacag caacggattc atttgtgact atgaacttca 200

 tgagctcttc aaggaagcta atatgccatt accaggatat aaagtgagag 250

 aaattattca gaaactcatg ctggatggtg acaggaataa agatgggaaa 300

 ataagttttg acgaatttgt ttatattttt caagaggtaa aaagtagtga 350

 tattgccaag accttccgca aagcaatcaa caggaaagaa ggtatttgtg 400

 ctctgggtgg aacttcagag ttgtccagcg aaggaacaca gcattcttac 450

 tcagaggaag aaaaatatgc ttttgttaac tggataaaca aagctttgga 500

 aaatgatcct gattgtagac atgttatacc aatgaaccct aacaccgatg 550

 acctgttcaa agctgttggt gatggaattg tgctttgtaa aatgattaac 600

 ctttcagttc ctgataccat tgatgaaaga gcaatcaaca agaagaaact 650

 tacacccttc atcattcagg aaaacttgaa cttggcactg aactctgctt 700

 ctgccattgg gtgtcatgtt gtgaacattg gtgcagaaga tttgagggct 750

 gggaaacctc atctggtttt gggactgctt tggcagatca ttaagatcgg 800

 tttgttcgct gacattgaat taagcaggaa tgaagccttg gctgctttac 850

 tccgagatgg tgagactttg gaggaactta tgaaattgtc tccagaagag 900

 cttctgctta gatgggcaaa ctttcatttg gaaaactcgg gctggcaaaa 950

 aattaacaac tttagtgctg acatcaagga ttccaaagcc tatttccatc 1000

 ttctcaatca aatcgcacca aaaggacaaa aggaaggtga accacggata 1050

 gatattaaca tgtcaggttt caatgaaaca gatgatttga agagagctga 1100

 gagtatgctt caacaagcag ataaattagg ttgcagacag tttgttaccc 1150

 ctgctgatgt tgtcagtgga aaccccaaac tcaacttagc tttcgtggct 1200

 aacctgttta ataaataccc agcactaact aagccagaga accaggatat 1250

 tgactggact ctattagaag gagaaactcg tgaagaaaga accttccgta 1300

 actggatgaa ctctcttggt gtcaatcctc acgtaaacca tctctatgct 1350

 gacctgcaag atgccctggt aatcttacag ttatatgaac gaattaaagt 1400

 tcctgttgac tggagtaagg ttaataaacc tccatacccg aaactgggag 1450

 ccaacatgaa aaagctagaa aactgcaact atgctgttga attagggaag 1500

 catcctgcta aattctccct ggttggcatt ggagggcaag acctgaatga 1550

 tgggaaccaa accctgactt tagctttagt ctggcagctg atgagaagat 1600

 ataccctcaa tgtcctggaa gatcttggag atggtcagaa agccaatgac 1650

 gacatcattg tgaactgggt gaacagaacg ttgagtgaag ctggaaaatc 1700

 aacttccatt cagagtttta aggacaagac gatcagctcc agtttggcag 1750

 ttgtggattt aattgatgcc atccagccag gctgtataaa ctatgacctt 1800

 gtgaagagtg gcaatctaac agaagatgac aagcacaata atgccaagta 1850

 tgcagtgtca atggctagaa gaatcggagc cagagtgtat gctctccctg 1900

 aagaccttgt ggaagtaaag cccaagatgg tcatgactgt gtttgcatgt 1950

 ttgatgggca ggggaatgaa gagagtgtaa aataaccaat ctgaataaaa 2000

 cagccatgct cccaggtgca tgattcgcag gtcagctatt tccaggtgaa 2050

 gtgcttatgg cttaaggaac tcttggccat tcaaaggact tttcattttg 2100

 attaacagga ctagcttatc atgagagccc tcaggggaaa gggtttaaga 2150

 aaaacaactc ctctttccca tagtcagagt tgaatttgtc aggcacgcct 2200

 gaaatgtgct catagccaaa acattttact ctctcctcct agaatgctgc 2250

 ccttgacatt tcccattgct gtatgttatt tcttgctctg ttatcttttg 2300

 ccctcttaga atgtccctct cttgggactt gcttagatga tgggatatga 2350

 atattattag acagtaattt tgctttccat ccagtatgct agttcttatt 2400

 cgagaactat ggtcagagcg tatttggata tgagtatcct ttgcttatct 2450

 ttgtagtact gaaaatttgc cgaagtaact ggctgtgcag aatgtaatag 2500

 aagcttttct tattctttta ttcttaagat cagtatcttt ttacagtatt 2550

 ctttctacat gatccttttt tgtacattta agaatatttt gattatatta 2600

 aacaagactg ctgattttgc tacttttttt aaggggtctt caagtaagta 2650

 aaacatacat cgtagctaga agaaaaatgt accttaaatt tgcatcttcc 2700

 ctctcatacc caagctgtaa acaattgaaa tattttgtct taaatcactt 2750

 ggttcaatac atgcttattt gttttaaaac ctgtatcatc aaactctctc 2800

 tctaaattta aaatgctgtt gaatatgata cttttgagga gagagtgtgc 2850

 tcagaactta gacgggattt ggtaggccaa gtatgctaag tgtacaatat 2900

 attttttaat tttacacctg aaacaaagaa atgtggtcac taaaaataaa 2950

 agtatatatg taggaattaa tgtactcttg ctttgtcaag ctgtttgcta 3000

 tagtttccaa ggtattatgt tactctaact ctgaaaagtg atgtaatctg 3050

 gtagcaatgt agtagttcaa ataaaggcat ttacataat 3089

<210> 240
<211> 630
<212> PRT
<213> Homo sapien

<400> 240
 Met Asp Glu Met Ala Thr Thr Gln Ile Ser Lys Asp Glu Leu Asp
   1               5                  10                  15

 Glu Leu Lys Glu Ala Phe Ala Lys Val Asp Leu Asn Ser Asn Gly
                  20                  25                  30

 Phe Ile Cys Asp Tyr Glu Leu His Glu Leu Phe Lys Glu Ala Asn
                  35                  40                  45

 Met Pro Leu Pro Gly Tyr Lys Val Arg Glu Ile Ile Gln Lys Leu
                  50                  55                  60

 Met Leu Asp Gly Asp Arg Asn Lys Asp Gly Lys Ile Ser Phe Asp
                  65                  70                  75

 Glu Phe Val Tyr Ile Phe Gln Glu Val Lys Ser Ser Asp Ile Ala
                  80                  85                  90

 Lys Thr Phe Arg Lys Ala Ile Asn Arg Lys Glu Gly Ile Cys Ala
                  95                 100                 105

 Leu Gly Gly Thr Ser Glu Leu Ser Ser Glu Gly Thr Gln His Ser
                 110                 115                 120

 Tyr Ser Glu Glu Glu Lys Tyr Ala Phe Val Asn Trp Ile Asn Lys
                 125                 130                 135

 Ala Leu Glu Asn Asp Pro Asp Cys Arg His Val Ile Pro Met Asn
                 140                 145                 150

 Pro Asn Thr Asp Asp Leu Phe Lys Ala Val Gly Asp Gly Ile Val
                 155                 160                 165

 Leu Cys Lys Met Ile Asn Leu Ser Val Pro Asp Thr Ile Asp Glu
                 170                 175                 180

 Arg Ala Ile Asn Lys Lys Lys Leu Thr Pro Phe Ile Ile Gln Glu
                 185                 190                 195

 Asn Leu Asn Leu Ala Leu Asn Ser Ala Ser Ala Ile Gly Cys His
                 200                 205                 210

 Val Val Asn Ile Gly Ala Glu Asp Leu Arg Ala Gly Lys Pro His
                 215                 220                 225

 Leu Val Leu Gly Leu Leu Trp Gln Ile Ile Lys Ile Gly Leu Phe
                 230                 235                 240

 Ala Asp Ile Glu Leu Ser Arg Asn Glu Ala Leu Ala Ala Leu Leu
                 245                 250                 255

 Arg Asp Gly Glu Thr Leu Glu Glu Leu Met Lys Leu Ser Pro Glu
                 260                 265                 270

 Glu Leu Leu Leu Arg Trp Ala Asn Phe His Leu Glu Asn Ser Gly
                 275                 280                 285

 Trp Gln Lys Ile Asn Asn Phe Ser Ala Asp Ile Lys Asp Ser Lys
                 290                 295                 300

 Ala Tyr Phe His Leu Leu Asn Gln Ile Ala Pro Lys Gly Gln Lys
                 305                 310                 315

 Glu Gly Glu Pro Arg Ile Asp Ile Asn Met Ser Gly Phe Asn Glu
                 320                 325                 330

 Thr Asp Asp Leu Lys Arg Ala Glu Ser Met Leu Gln Gln Ala Asp
                 335                 340                 345

 Lys Leu Gly Cys Arg Gln Phe Val Thr Pro Ala Asp Val Val Ser
                 350                 355                 360

 Gly Asn Pro Lys Leu Asn Leu Ala Phe Val Ala Asn Leu Phe Asn
                 365                 370                 375

 Lys Tyr Pro Ala Leu Thr Lys Pro Glu Asn Gln Asp Ile Asp Trp
                 380                 385                 390

 Thr Leu Leu Glu Gly Glu Thr Arg Glu Glu Arg Thr Phe Arg Asn
                 395                 400                 405

 Trp Met Asn Ser Leu Gly Val Asn Pro His Val Asn His Leu Tyr
                 410                 415                 420

 Ala Asp Leu Gln Asp Ala Leu Val Ile Leu Gln Leu Tyr Glu Arg
                 425                 430                 435

 Ile Lys Val Pro Val Asp Trp Ser Lys Val Asn Lys Pro Pro Tyr
                 440                 445                 450

 Pro Lys Leu Gly Ala Asn Met Lys Lys Leu Glu Asn Cys Asn Tyr
                 455                 460                 465

 Ala Val Glu Leu Gly Lys His Pro Ala Lys Phe Ser Leu Val Gly
                 470                 475                 480

 Ile Gly Gly Gln Asp Leu Asn Asp Gly Asn Gln Thr Leu Thr Leu
                 485                 490                 495

 Ala Leu Val Trp Gln Leu Met Arg Arg Tyr Thr Leu Asn Val Leu
                 500                 505                 510

 Glu Asp Leu Gly Asp Gly Gln Lys Ala Asn Asp Asp Ile Ile Val
                 515                 520                 525

 Asn Trp Val Asn Arg Thr Leu Ser Glu Ala Gly Lys Ser Thr Ser
                 530                 535                 540

 Ile Gln Ser Phe Lys Asp Lys Thr Ile Ser Ser Ser Leu Ala Val
                 545                 550                 555

 Val Asp Leu Ile Asp Ala Ile Gln Pro Gly Cys Ile Asn Tyr Asp
                 560                 565                 570

 Leu Val Lys Ser Gly Asn Leu Thr Glu Asp Asp Lys His Asn Asn
                 575                 580                 585

 Ala Lys Tyr Ala Val Ser Met Ala Arg Arg Ile Gly Ala Arg Val
                 590                 595                 600

 Tyr Ala Leu Pro Glu Asp Leu Val Glu Val Lys Pro Lys Met Val
                 605                 610                 615

 Met Thr Val Phe Ala Cys Leu Met Gly Arg Gly Met Lys Arg Val
                 620                 625                 630

<210> 241
<211> 1311
<212> DNA
<213> Homo sapien

<400> 241
 ctctaccggc gggatttgat ggcgtgatgt ctcacagaaa gttctccgct 50

 cccagacatg ggtccctcgg cttcctgcct cggaagcgca gcagcaggca 100

 tcgtgggaag gtgaagagct tccctaagga tgacccgtcc aagccggtcc 150

 acctcacagc cttcctggga tacaaggctg gcatgactca catcgtgcgg 200

 gaagtcgaca ggccgggatc caaggtgaac aagaaggagg tggtggaggc 250

 tgtgaccatt gtagagacac cacccatggt ggttgtgggc attgtgggct 300

 acgtggaaac ccctcgaggc ctccggacct tcaagactgt ctttgctgag 350

 cacatcagtg atgaatgcaa gaggcgtttc tataagaatt ggcataaatc 400

 taagaagaag gcctttacca agtactgcaa gaaatggcag gatgaggatg 450

 gcaagaagca gctggagaag gacttcagca gcatgaagaa gtactgccaa 500

 gtcatccgtg tcattgccca cacccagatg cgcctgcttc ctctgcgcca 550

 gaagaaggcc cacctgatgg agatccaggt gaacggaggc actgtggccg 600

 agaagctgga ctgggcccgc gagaggcttg agcagcaggt acctgtgaac 650

 caagtgtttg ggcaggatga gatgatcgac gtcatcgggg tgaccaaggg 700

 caaaggctac aaaggggtca ccagtcgttg gcacaccaag aagctgcccc 750

 gcaagaccca ccgaggcctg cgcaaggtgg cctgtattgg ggcatggcat 800

 cctgctcgtg tagccttctc tgtggcacgc gctgggcaga aaggctacca 850

 tcaccgcact gagatcaaca agaagattta taagattggc cagggctacc 900

 ttatcaagga cggcaagctg atcaagaaca atgcctccac tgactatgac 950

 ctatctgaca agagcatcaa ccctctgggt ggctttgtcc actatggtga 1000

 agtgaccaat gactttgtca tgctgaaagg ctgtgtggtg ggaaccaaga 1050

 agcgggtgct caccctccgc aagtccttgc tggtgcagac gaagcggcgg 1100

 gctctggaga agattgacct taagttcatt gacaccacct ccaagtttgg 1150

 ccatggccgc ttccagacca tggaggagaa gaaagcattc atgggaccac 1200

 tgaagaaaga ccgaattgca aaggaagaag gagcttaatg ccaggaacag 1250

 attttgcagt tggtggggtc tcaataaaag ttattttcca ctgaaaaaaa 1300

 aaaaaaaaaa a 1311

<210> 242
<211> 403
<212> PRT
<213> Homo sapien

<400> 242
 Met Ser His Arg Lys Phe Ser Ala Pro Arg His Gly Ser Leu Gly
   1               5                  10                  15

 Phe Leu Pro Arg Lys Arg Ser Ser Arg His Arg Gly Lys Val Lys
                  20                  25                  30

 Ser Phe Pro Lys Asp Asp Pro Ser Lys Pro Val His Leu Thr Ala
                  35                  40                  45

 Phe Leu Gly Tyr Lys Ala Gly Met Thr His Ile Val Arg Glu Val
                  50                  55                  60

 Asp Arg Pro Gly Ser Lys Val Asn Lys Lys Glu Val Val Glu Ala
                  65                  70                  75

 Val Thr Ile Val Glu Thr Pro Pro Met Val Val Val Gly Ile Val
                  80                  85                  90

 Gly Tyr Val Glu Thr Pro Arg Gly Leu Arg Thr Phe Lys Thr Val
                  95                 100                 105

 Phe Ala Glu His Ile Ser Asp Glu Cys Lys Arg Arg Phe Tyr Lys
                 110                 115                 120

 Asn Trp His Lys Ser Lys Lys Lys Ala Phe Thr Lys Tyr Cys Lys
                 125                 130                 135

 Lys Trp Gln Asp Glu Asp Gly Lys Lys Gln Leu Glu Lys Asp Phe
                 140                 145                 150

 Ser Ser Met Lys Lys Tyr Cys Gln Val Ile Arg Val Ile Ala His
                 155                 160                 165

 Thr Gln Met Arg Leu Leu Pro Leu Arg Gln Lys Lys Ala His Leu
                 170                 175                 180

 Met Glu Ile Gln Val Asn Gly Gly Thr Val Ala Glu Lys Leu Asp
                 185                 190                 195

 Trp Ala Arg Glu Arg Leu Glu Gln Gln Val Pro Val Asn Gln Val
                 200                 205                 210

 Phe Gly Gln Asp Glu Met Ile Asp Val Ile Gly Val Thr Lys Gly
                 215                 220                 225

 Lys Gly Tyr Lys Gly Val Thr Ser Arg Trp His Thr Lys Lys Leu
                 230                 235                 240

 Pro Arg Lys Thr His Arg Gly Leu Arg Lys Val Ala Cys Ile Gly
                 245                 250                 255

 Ala Trp His Pro Ala Arg Val Ala Phe Ser Val Ala Arg Ala Gly
                 260                 265                 270

 Gln Lys Gly Tyr His His Arg Thr Glu Ile Asn Lys Lys Ile Tyr
                 275                 280                 285

 Lys Ile Gly Gln Gly Tyr Leu Ile Lys Asp Gly Lys Leu Ile Lys
                 290                 295                 300

 Asn Asn Ala Ser Thr Asp Tyr Asp Leu Ser Asp Lys Ser Ile Asn
                 305                 310                 315

 Pro Leu Gly Gly Phe Val His Tyr Gly Glu Val Thr Asn Asp Phe
                 320                 325                 330

 Val Met Leu Lys Gly Cys Val Val Gly Thr Lys Lys Arg Val Leu
                 335                 340                 345

 Thr Leu Arg Lys Ser Leu Leu Val Gln Thr Lys Arg Arg Ala Leu
                 350                 355                 360

 Glu Lys Ile Asp Leu Lys Phe Ile Asp Thr Thr Ser Lys Phe Gly
                 365                 370                 375

 His Gly Arg Phe Gln Thr Met Glu Glu Lys Lys Ala Phe Met Gly
                 380                 385                 390

 Pro Leu Lys Lys Asp Arg Ile Ala Lys Glu Glu Gly Ala
                 395                 400

<210> 243
<211> 2943
<212> DNA
<213> Homo sapien

<400> 243
 gagtcacgat gatggcggcc accatcctgt ggtgagctag cggattccct 50

 gcttgtctcg ccgaccccct cgcgccttct gcagactccg tggctggcgc 100

 tcggcgcgtg aggaagcacg gcggcccgag ttcgcgggga aggccgcagt 150

 cgcggaggca gcggcgcggt ccggggcacg ggctggggga gaggccgctc 200

 cgctgggcga atgtgacaag cccccacccc caccgccttc ctccccagag 250

 cgcgaggagc gcgggcgacc ccggggcccc gccaggccac agaccccgcc 300

 cagcggccag cacccggcgc aggcccggca gccgagctgc gcggcggcac 350

 catgcaggtc accctgaaga ccctccagca gcagaccttc aagatagaca 400

 ttgaccccga ggagacggtg aaagcactga aagagaagat tgaatctgaa 450

 aaggggaaag atgcctttcc agtagcaggt caaaaattaa tttatgcagg 500

 caaaatcctc aatgatgata ctgctctcaa agaatataaa attgatgaga 550

 aaaactttgt ggtggttatg gtgaccaaac ccaaagcagt gtccacacca 600

 gcaccagcta caactcagca gtcagctcct gccagcacta cagcagttac 650

 ttcctccacc accacaactg tggctcaggc tccaacccct gtccctgcct 700

 tggcccccac ttccacacct gcatccatca ctccagcatc agcgacagca 750

 tcttctgaac ctgcacctgc tagtgcagct aaacaagaga agcctgcaga 800

 aaagccagca gagacaccag tggctactag cccaacagca actgacagta 850

 catcgggtga ttcttctcgg tcaaaccttt ttgaagatgc aacgagtgca 900

 cttgtgacgg gtcagtctta cgagaatatg gtaactgaga tcatgtcaat 950

 gggctatgaa cgagagcaag taattgcagc cctgagagcc agtttcaaca 1000

 accctgacag agcagtggag tatcttttaa tgggaatccc tggagataga 1050

 gaaagtcagg ctgtggttga cccccctcaa gcagctagta ctggggctcc 1100

 tcagtcttca gcagtggctg cagctgcagc aactacgaca gcaacaacta 1150

 caacaacaag ttctggagga catccccttg aatttttacg gaatcagcct 1200

 cagtttcaac agatgagaca aattattcag cagaatcctt ccttgcttcc 1250

 agcgttacta cagcagatag gtcgagagaa tcctcaatta cttcagcaaa 1300

 ttagccaaca ccaggagcat tttattcaga tgttaaatga accagttcaa 1350

 gaagctggtg gtcaaggagg aggaggtgga ggtggcagtg gaggaattgc 1400

 agaagctgga agtggtcata tgaactacat tcaagtaaca cctcaggaaa 1450

 aagaagctat agaaaggtta aaggcattag gatttcctga aggacttgtg 1500

 atacaagcgt attttgcttg tgagaagaat gagaatttgg ctgccaattt 1550

 tcttctacag cagaactttg atgaagattg aaagggactt ttttatatct 1600

 cacacttcac accagtgcat tacactaact tgttcactgg attgtctggg 1650

 atgacttggg ctcatatcca caatacttgg tataaggtag tagattgttg 1700

 ggggtgggga gggagggatc taggatacag ggcagggata aatacagtgc 1750

 atgtctgctt caattagcag atgccgcaac tccacacagt gtgtaaaata 1800

 tatacaacca aaaatcagct tttgcaggtc tttatttctt ctgtaaaaca 1850

 gtaggtaact tttcctaggt ttcactcttt ttagtgtact agatccagaa 1900

 acttagtgta atgccctgct ttatatttct ttgacttaac attggtttca 1950

 gaaagaatct tagctaccta gaatttacag tctctgtttc atggcaacac 2000

 tggataatgg ctttgtgaaa tttaaaaaat ttttgtagcg actgtaaaca 2050

 gaaatgccaa attgatggtt aattgttgct gcttcaaaaa taagtataaa 2100

 attaatatgt aaggaagccc attctttcat gttaaatact tggggtggga 2150

 ggggagaaag ggaacctttt cttaaaatga aaataattac tgctatttta 2200

 aaatttcttg atcattgaat gtgagaccct tctaacatga tttgagaagc 2250

 tgtacaagta taggcagagt tattttcctg tttacatttt ttttttgttt 2300

 tggggaaaaa attggtaggt gtctaattac tgtttacttc attgttatat 2350

 tgcagtaaaa gttttaaaac aaccattgca tgtttgcttt tgatgtatcc 2400

 ctttgtgaaa ttagcacttt tggggccaat ggagaaatgc agcattcact 2450

 ctccctgtct tttccccttc cctcagcaga aacgtgttta tcagcaagtc 2500

 gtgagtcaaa ctgctgcctt ttaaaaaacc cacaaaatgc tgattcagtt 2550

 caaaattaat gcaaatgttt caaaactggg tttctgatat ttgtaaatgt 2600

 gtttctttat tagataagag tgtattacca ttaaagtcat tagtataata 2650

 ttgctttcaa aaagaaatgg tagacaaaac tataatccag catcttttat 2700

 tgcattggaa agactggcaa agtcttttgg atgggttggg agatgtggct 2750

 ggaaagtact ttggaaaata tacaatcaag atatctcatg gcatattaaa 2800

 agaaaaatct taatagcagt gttggctttt atttggattt tttcatctca 2850

 gttttttctg tggaatctcc ttcattggca ttgttattta atcataaacg 2900

 gggcagatgt ctacttgttc agtttttcaa atctgttttc ctg 2943

<210> 244
<211> 409
<212> PRT
<213> Homo sapien

<400> 244
 Met Gln Val Thr Leu Lys Thr Leu Gln Gln Gln Thr Phe Lys Ile
   1               5                  10                  15

 Asp Ile Asp Pro Glu Glu Thr Val Lys Ala Leu Lys Glu Lys Ile
                  20                  25                  30

 Glu Ser Glu Lys Gly Lys Asp Ala Phe Pro Val Ala Gly Gln Lys
                  35                  40                  45

 Leu Ile Tyr Ala Gly Lys Ile Leu Asn Asp Asp Thr Ala Leu Lys
                  50                  55                  60

 Glu Tyr Lys Ile Asp Glu Lys Asn Phe Val Val Val Met Val Thr
                  65                  70                  75

 Lys Pro Lys Ala Val Ser Thr Pro Ala Pro Ala Thr Thr Gln Gln
                  80                  85                  90

 Ser Ala Pro Ala Ser Thr Thr Ala Val Thr Ser Ser Thr Thr Thr
                  95                 100                 105

 Thr Val Ala Gln Ala Pro Thr Pro Val Pro Ala Leu Ala Pro Thr
                 110                 115                 120

 Ser Thr Pro Ala Ser Ile Thr Pro Ala Ser Ala Thr Ala Ser Ser
                 125                 130                 135

 Glu Pro Ala Pro Ala Ser Ala Ala Lys Gln Glu Lys Pro Ala Glu
                 140                 145                 150

 Lys Pro Ala Glu Thr Pro Val Ala Thr Ser Pro Thr Ala Thr Asp
                 155                 160                 165

 Ser Thr Ser Gly Asp Ser Ser Arg Ser Asn Leu Phe Glu Asp Ala
                 170                 175                 180

 Thr Ser Ala Leu Val Thr Gly Gln Ser Tyr Glu Asn Met Val Thr
                 185                 190                 195

 Glu Ile Met Ser Met Gly Tyr Glu Arg Glu Gln Val Ile Ala Ala
                 200                 205                 210

 Leu Arg Ala Ser Phe Asn Asn Pro Asp Arg Ala Val Glu Tyr Leu
                 215                 220                 225

 Leu Met Gly Ile Pro Gly Asp Arg Glu Ser Gln Ala Val Val Asp
                 230                 235                 240

 Pro Pro Gln Ala Ala Ser Thr Gly Ala Pro Gln Ser Ser Ala Val
                 245                 250                 255

 Ala Ala Ala Ala Ala Thr Thr Thr Ala Thr Thr Thr Thr Thr Ser
                 260                 265                 270

 Ser Gly Gly His Pro Leu Glu Phe Leu Arg Asn Gln Pro Gln Phe
                 275                 280                 285

 Gln Gln Met Arg Gln Ile Ile Gln Gln Asn Pro Ser Leu Leu Pro
                 290                 295                 300

 Ala Leu Leu Gln Gln Ile Gly Arg Glu Asn Pro Gln Leu Leu Gln
                 305                 310                 315

 Gln Ile Ser Gln His Gln Glu His Phe Ile Gln Met Leu Asn Glu
                 320                 325                 330

 Pro Val Gln Glu Ala Gly Gly Gln Gly Gly Gly Gly Gly Gly Gly
                 335                 340                 345

 Ser Gly Gly Ile Ala Glu Ala Gly Ser Gly His Met Asn Tyr Ile
                 350                 355                 360

 Gln Val Thr Pro Gln Glu Lys Glu Ala Ile Glu Arg Leu Lys Ala
                 365                 370                 375

 Leu Gly Phe Pro Glu Gly Leu Val Ile Gln Ala Tyr Phe Ala Cys
                 380                 385                 390

 Glu Lys Asn Glu Asn Leu Ala Ala Asn Phe Leu Leu Gln Gln Asn
                 395                 400                 405

 Phe Asp Glu Asp


<210> 245
<211> 2718
<212> DNA
<213> Homo sapien

<400> 245
 cagggtaacg ctgtcttgtg gacccgcact tcccacccga gacctctcac 50

 tgagcccgag ccgcgcgcga catgagccac gggaagggaa ccgacatgct 100

 cccggagatc gccgccgccg tgggcttcct ctccagcctc ctgaggaccc 150

 ggggctgcgt gagcgagcag aggcttaagg tcttcagcgg ggcgctccag 200

 gaggcactca cagagcacta caaacaccac tggtttcccg aaaagccgtc 250

 caagggctcc ggctaccgct gcattcgcat caaccacaag atggacccca 300

 tcatcagcag ggtggccagc cagatcggac tcagccagcc ccagctgcac 350

 cagctgctgc ccagcgagct gaccctgtgg gtggacccct atgaggtgtc 400

 ctaccgcatt ggggaggacg gctccatctg cgtcttgtac gaggaggccc 450

 cactggccgc ctcctgtggg ctcctcacct gcaagaacca agtgctgctg 500

 ggccggagca gcccctccaa gaactacgtg atggcagtct ccagctaggc 550

 ccttccgccc ccgccctggg cgccgccgtg ctcatgctgc cgtgacaaca 600

 ggccaccaca tacctcaacc tggggaactg tatttttaaa tgaagagcta 650

 tttatatata ttattttttt ttaagaaagg aggaaaagaa accaaaagtt 700

 ttttttaaga aaaaaaatcc ttcaagggag ctgcttggaa gtggcctccc 750

 caggtgcctt tggagagaac tgttgcgtgc ttgagtctgt gagccagtgt 800

 ctgcctatag gagggggagc tgttaggggg tagacctagc caaggagaag 850

 tgggagacgt ttggctagca ccccaggaag atgtgagagg gagcaagcaa 900

 ggttagcaac tgtgaacaga gaggtcggga tttgccctgg gggaggaaga 950

 gaggccaagt tcagagctct ctgtctcccc cagccagaca cctgcatccc 1000

 tggctcctct attactcagg ggcattcatg cctggactta aacaatacta 1050

 tgttatcttt tcttttattt ttctaatgag gtcctgggca gagagtgaaa 1100

 aggcctctcc tgattcctac tgtcctaagc tgcttttctt gaaatcatga 1150

 cttgtttcta attctaccct caggggcctg tagatgttgc tttccagcca 1200

 ggaatctaaa gctttgggtt ttctgagggg ggggaggagg gaactggagg 1250

 ttattggggt taggatggaa gggaactctg cacaaaacct ttgctttgct 1300

 agtgctgctt tgtgtgtatg tgtggcaaat aatttggggg tgatttgcaa 1350

 tgaaattttg ggacccaaag agtatccact ggggatgttt tttggccaaa 1400

 actcttcctt ttggaaccac atgaaagtct tgatgctgct gccatgatcc 1450

 ctttgagagg tggctcaaaa gctacaggga actccaggtc ctttattact 1500

 gccttctttt caaaagcaca actctcctct aaccctcccc tcccccttcc 1550

 cttctggtcg ggtcatagag ctaccgtatt ttctaggaca agagttctca 1600

 gtcactgtgc aatatgcccc ctgggtccca ggagggtctg gaggaaaact 1650

 ggctatcaga acctcctgat gccctggtgg gcttagggaa ccatctctcc 1700

 tgctctcctt gggatgatgg ctggctagtc agccttgcat gtattccttg 1750

 gctgaatggg agagtgcccc atgttctgca agactacttg gtattcttgt 1800

 agggccgaca ctaaataaaa gccaaacctt gggcactgtt ttttctccct 1850

 ggtgctcaga gcacctgtgg gaaaggttgc tgtctgtctc agtacaatcc 1900

 aaatttgtcg tagacttgtg caatatatac tgttgtgggt tggagaaaag 1950

 tggaaagcta cactgggaag aaactccctt ccttcaattt ctcagtgaca 2000

 ttgatgaggg gtcctcaaaa gacctcgagt ttcccaaacc gaatcacctt 2050

 aagaaggaca gggctagggc atttggccag gatggccacc ctcctgctgt 2100

 tgccccttag tgaggaatct tcaccccact tcctctaccc ccaggttctc 2150

 ctccccacag ccagtcccct ttcctggatt tctaaactgc tcaattttga 2200

 ctcaaaggtg ctatttacca aacactctcc ctacccattc ctgccagctc 2250

 tgcctccttt tcaactctcc acattttgta ttgccttccc agacctgctt 2300

 ccagtcttta ttgctttaaa gttcactttg ggcccacaga cccaagagct 2350

 aattttctgg tttgtgggtt gaaacaaagc tgtgaatcac tgcaggctgt 2400

 gttcttgcat cttgtctgca aacaggtccc tgccttttta gaagcagcct 2450

 catggtctca tgcttaatct tgtctctctt ctcttcttta tgatgttcac 2500

 tttaaaaaca acaaaacccc tgagctggac tgttgagcag gcctgtctct 2550

 cctattaagt aaaaataaat agtagtagta tgtttgtaag ctattctgac 2600

 agaaaagaca aaggttacta attgtatgat agtgttttta tatggaagaa 2650

 tgtacagctt atggacaaat gtacaccttt ttgttacttt aataaaaatg 2700

 tagtaggata aaaaaaaa 2718

<210> 246
<211> 158
<212> PRT
<213> Homo sapien

<400> 246
 Met Ser His Gly Lys Gly Thr Asp Met Leu Pro Glu Ile Ala Ala
   1               5                  10                  15

 Ala Val Gly Phe Leu Ser Ser Leu Leu Arg Thr Arg Gly Cys Val
                  20                  25                  30

 Ser Glu Gln Arg Leu Lys Val Phe Ser Gly Ala Leu Gln Glu Ala
                  35                  40                  45

 Leu Thr Glu His Tyr Lys His His Trp Phe Pro Glu Lys Pro Ser
                  50                  55                  60

 Lys Gly Ser Gly Tyr Arg Cys Ile Arg Ile Asn His Lys Met Asp
                  65                  70                  75

 Pro Ile Ile Ser Arg Val Ala Ser Gln Ile Gly Leu Ser Gln Pro
                  80                  85                  90

 Gln Leu His Gln Leu Leu Pro Ser Glu Leu Thr Leu Trp Val Asp
                  95                 100                 105

 Pro Tyr Glu Val Ser Tyr Arg Ile Gly Glu Asp Gly Ser Ile Cys
                 110                 115                 120

 Val Leu Tyr Glu Glu Ala Pro Leu Ala Ala Ser Cys Gly Leu Leu
                 125                 130                 135

 Thr Cys Lys Asn Gln Val Leu Leu Gly Arg Ser Ser Pro Ser Lys
                 140                 145                 150

 Asn Tyr Val Met Ala Val Ser Ser
                 155

<210> 247
<211> 2706
<212> DNA
<213> Homo sapien

<400> 247
 ctctgtagct gtgaccctga taccgcgtgg tgtgctccga acacatggtg 50

 cccagaacga aggcggcgtc cagaagccct aggtcccaga ggtccgctca 100

 gcggcaggcg cataaggcgg ggccggcgcg ggcctttcct tccatcggaa 150

 ccgttctccc ggggctgagt ccctgcccgg actccgaacg ccgaagacca 200

 ggggccggaa gcgcgcgccg ccactgccac gccgtgtcag tcgggaggga 250

 gggagcgagc aggcgaagcc gcggaggacg gggtgaagat ggcggccttc 300

 tccgagatgg gtgtaatgcc tgagattgca caagctgtgg aagagatgga 350

 ttggctcctc ccaactgata tccaggctga atctatccca ttgatcttag 400

 gaggaggtga tgtacttatg gctgcagaaa caggaagtgg caaaactggt 450

 gcttttagta ttccagttat ccagatagtt tatgaaactc tgaaagacca 500

 acaggaaggc aaaaaaggaa aaacaacaat taaaactggt gcttcagtgc 550

 tgaacaaatg gcagatgaac ccatatgaca gaggatctgc ttttgcaatt 600

 gggtcagatg gtctttgttg tcaaagcaga gaagtaaagg aatggcatgg 650

 gtgtagagct actaaaggat taatgaaagg gaaacactac tatgaagtat 700

 cctgtcatga ccaagggtta tgcagggtcg ggtggtctac catgcaggcc 750

 tctttggacc taggtactga caagtttgga tttggctttg gtggaacagg 800

 aaagaaatcc cataacaaac aatttgataa ttatggagag gaattcacta 850

 tgcatgatac cattggatgt tacctggata tagataaggg acatgtcaag 900

 ttctccaaaa atggaaaaga tcttggtctg gcatttgaaa taccaccaca 950

 tatgaaaaac caagccctct ttcctgcctg tgttttgaag aatgctgaac 1000

 tgaaatttaa cttcggtgaa gaggaattta agtttccacc aaaagatggc 1050

 tttgttgctc tttccaaggc accggatggt tacattgtca aatcacagca 1100

 ctcaggtaat gcacaggtga cacaaacaaa gtttctcccc aatgctccga 1150

 aagctctcat tgttgaacct tcccgggagt tagctgaaca aactttgaac 1200

 aacatcaagc agtttaagaa atacattgat aatcctaaat taagggagct 1250

 tctgataatt ggaggtgttg cagcccggga tcagctctct gttttggaaa 1300

 atggagtaga tatagttgta ggtactccgg gaagactaga tgacttggtg 1350

 tcaactggaa agctgaactt atctcaagtt agattcctgg tcctggatga 1400

 agctgatggg cttctttctc aaggttattc tgattttata aataggatgc 1450

 acaatcagat tcctcaggtt acctctgatg gaaaaagact tcaggtgatt 1500

 gtttgctctg ccactttgca ttctttcgat gtaaagaaac tgtccgagaa 1550

 gataatgcat tttcctacat gggttgactt aaaaggagaa gactctgttc 1600

 cagatactgt acaccatgtt gttgtcccag taaatcccaa aactgacaga 1650

 ctctgggaaa ggcttggaaa gagccacatt agaactgatg atgtacatgc 1700

 aaaagataac acaagacctg gtgctaatag tccagagatg tggtctgaag 1750

 ctattaaaat cctgaaaggg gagtatgctg tccgggcaat caaggaacat 1800

 aagatggatc aagcaattat cttctgtaga accaaaattg actgtgataa 1850

 cttggagcag tactttatac aacaaggagg aggacctgat aaaaaaggac 1900

 accagttctc atgtgtttgt cttcatggtg acagaaagcc tcatgagaga 1950

 aagcaaaact tggaaagatt taagaaagga gatgtaagat tcttgatttg 2000

 cacagatgta gctgctagag gaattgatat ccacggtgtt ccttatgtta 2050

 taaatgtcac tctgcccgat gaaaagcaaa actacgtaca tcgaattggc 2100

 agagtaggaa gagctgaaag gatgggtctg gcaatttccc tggtggcaac 2150

 agaaaaagaa aaggtttggt accatgtatg tagcagccgt ggaaaagggt 2200

 gttataacac aagactcaag gaagatggag gctgtaccat atggtacaac 2250

 gagatgcagt tactatctga gatagaagaa cacctgaact gtaccatttc 2300

 tcaggttgag ccggatataa aggtaccagt ggatgaattt gatgggaaag 2350

 ttacctacgg tcagaaaagg gctgctggtg gtggaagcta taaaggccat 2400

 gtggatattt tggcacctac tgttcaagag ttggctgccc ttgaaaagga 2450

 ggcgcagaca tctttcctgc atcttggcta ccttcctaac cagctgttca 2500

 gaaccttctg atttttacat ttactgaata agatttgagt aatgaaagtc 2550

 tgtagtctta aaactctaaa acagttgtac tgcttccaag cagcagtatt 2600

 tatagtaacg taagctatta atgctaactc ttgcatgtca agaaacatta 2650

 gtcttaggaa ttcttcaaaa aatggcatcc caatgaaaat aaatttgatg 2700

 actata 2706

<210> 248
<211> 740
<212> PRT
<213> Homo sapien

<400> 248
 Met Ala Ala Phe Ser Glu Met Gly Val Met Pro Glu Ile Ala Gln
   1               5                  10                  15

 Ala Val Glu Glu Met Asp Trp Leu Leu Pro Thr Asp Ile Gln Ala
                  20                  25                  30

 Glu Ser Ile Pro Leu Ile Leu Gly Gly Gly Asp Val Leu Met Ala
                  35                  40                  45

 Ala Glu Thr Gly Ser Gly Lys Thr Gly Ala Phe Ser Ile Pro Val
                  50                  55                  60

 Ile Gln Ile Val Tyr Glu Thr Leu Lys Asp Gln Gln Glu Gly Lys
                  65                  70                  75

 Lys Gly Lys Thr Thr Ile Lys Thr Gly Ala Ser Val Leu Asn Lys
                  80                  85                  90

 Trp Gln Met Asn Pro Tyr Asp Arg Gly Ser Ala Phe Ala Ile Gly
                  95                 100                 105

 Ser Asp Gly Leu Cys Cys Gln Ser Arg Glu Val Lys Glu Trp His
                 110                 115                 120

 Gly Cys Arg Ala Thr Lys Gly Leu Met Lys Gly Lys His Tyr Tyr
                 125                 130                 135

 Glu Val Ser Cys His Asp Gln Gly Leu Cys Arg Val Gly Trp Ser
                 140                 145                 150

 Thr Met Gln Ala Ser Leu Asp Leu Gly Thr Asp Lys Phe Gly Phe
                 155                 160                 165

 Gly Phe Gly Gly Thr Gly Lys Lys Ser His Asn Lys Gln Phe Asp
                 170                 175                 180

 Asn Tyr Gly Glu Glu Phe Thr Met His Asp Thr Ile Gly Cys Tyr
                 185                 190                 195

 Leu Asp Ile Asp Lys Gly His Val Lys Phe Ser Lys Asn Gly Lys
                 200                 205                 210

 Asp Leu Gly Leu Ala Phe Glu Ile Pro Pro His Met Lys Asn Gln
                 215                 220                 225

 Ala Leu Phe Pro Ala Cys Val Leu Lys Asn Ala Glu Leu Lys Phe
                 230                 235                 240

 Asn Phe Gly Glu Glu Glu Phe Lys Phe Pro Pro Lys Asp Gly Phe
                 245                 250                 255

 Val Ala Leu Ser Lys Ala Pro Asp Gly Tyr Ile Val Lys Ser Gln
                 260                 265                 270

 His Ser Gly Asn Ala Gln Val Thr Gln Thr Lys Phe Leu Pro Asn
                 275                 280                 285

 Ala Pro Lys Ala Leu Ile Val Glu Pro Ser Arg Glu Leu Ala Glu
                 290                 295                 300

 Gln Thr Leu Asn Asn Ile Lys Gln Phe Lys Lys Tyr Ile Asp Asn
                 305                 310                 315

 Pro Lys Leu Arg Glu Leu Leu Ile Ile Gly Gly Val Ala Ala Arg
                 320                 325                 330

 Asp Gln Leu Ser Val Leu Glu Asn Gly Val Asp Ile Val Val Gly
                 335                 340                 345

 Thr Pro Gly Arg Leu Asp Asp Leu Val Ser Thr Gly Lys Leu Asn
                 350                 355                 360

 Leu Ser Gln Val Arg Phe Leu Val Leu Asp Glu Ala Asp Gly Leu
                 365                 370                 375

 Leu Ser Gln Gly Tyr Ser Asp Phe Ile Asn Arg Met His Asn Gln
                 380                 385                 390

 Ile Pro Gln Val Thr Ser Asp Gly Lys Arg Leu Gln Val Ile Val
                 395                 400                 405

 Cys Ser Ala Thr Leu His Ser Phe Asp Val Lys Lys Leu Ser Glu
                 410                 415                 420

 Lys Ile Met His Phe Pro Thr Trp Val Asp Leu Lys Gly Glu Asp
                 425                 430                 435

 Ser Val Pro Asp Thr Val His His Val Val Val Pro Val Asn Pro
                 440                 445                 450

 Lys Thr Asp Arg Leu Trp Glu Arg Leu Gly Lys Ser His Ile Arg
                 455                 460                 465

 Thr Asp Asp Val His Ala Lys Asp Asn Thr Arg Pro Gly Ala Asn
                 470                 475                 480

 Ser Pro Glu Met Trp Ser Glu Ala Ile Lys Ile Leu Lys Gly Glu
                 485                 490                 495

 Tyr Ala Val Arg Ala Ile Lys Glu His Lys Met Asp Gln Ala Ile
                 500                 505                 510

 Ile Phe Cys Arg Thr Lys Ile Asp Cys Asp Asn Leu Glu Gln Tyr
                 515                 520                 525

 Phe Ile Gln Gln Gly Gly Gly Pro Asp Lys Lys Gly His Gln Phe
                 530                 535                 540

 Ser Cys Val Cys Leu His Gly Asp Arg Lys Pro His Glu Arg Lys
                 545                 550                 555

 Gln Asn Leu Glu Arg Phe Lys Lys Gly Asp Val Arg Phe Leu Ile
                 560                 565                 570

 Cys Thr Asp Val Ala Ala Arg Gly Ile Asp Ile His Gly Val Pro
                 575                 580                 585

 Tyr Val Ile Asn Val Thr Leu Pro Asp Glu Lys Gln Asn Tyr Val
                 590                 595                 600

 His Arg Ile Gly Arg Val Gly Arg Ala Glu Arg Met Gly Leu Ala
                 605                 610                 615

 Ile Ser Leu Val Ala Thr Glu Lys Glu Lys Val Trp Tyr His Val
                 620                 625                 630

 Cys Ser Ser Arg Gly Lys Gly Cys Tyr Asn Thr Arg Leu Lys Glu
                 635                 640                 645

 Asp Gly Gly Cys Thr Ile Trp Tyr Asn Glu Met Gln Leu Leu Ser
                 650                 655                 660

 Glu Ile Glu Glu His Leu Asn Cys Thr Ile Ser Gln Val Glu Pro
                 665                 670                 675

 Asp Ile Lys Val Pro Val Asp Glu Phe Asp Gly Lys Val Thr Tyr
                 680                 685                 690

 Gly Gln Lys Arg Ala Ala Gly Gly Gly Ser Tyr Lys Gly His Val
                 695                 700                 705

 Asp Ile Leu Ala Pro Thr Val Gln Glu Leu Ala Ala Leu Glu Lys
                 710                 715                 720

 Glu Ala Gln Thr Ser Phe Leu His Leu Gly Tyr Leu Pro Asn Gln
                 725                 730                 735

 Leu Phe Arg Thr Phe
                 740

<210> 249
<211> 2208
<212> DNA
<213> Homo sapien

<400> 249
 gaattcatgc taaattgctg gaaggctgcg tctctgctgt ggtgtcagtt 50

 ccggatgcct catcgccagg ggcgcgccgc agccacccac cctccggacc 100

 gcggcagctg ctgacccgcc atcgccatgg cccgcgggaa agccaaggag 150

 gagggcagct ggaagaaatt catctggaac tcagagaaga aggagtttct 200

 gggcaggacc ggtggcagtt ggtttaagat ccttctattc tacgtaatat 250

 tttatggctg cctggctggc atcttcatcg gaaccatcca agtgatgctg 300

 ctcaccatca gtgaatttaa gcccacatat caggaccgag tggccccgcc 350

 aggattaaca cagattcctc agatccagaa gactgaaatt tcctttcgtc 400

 ctaatgatcc caagagctat gaggcatatg tactgaacat agttaggttc 450

 ctggaaaagt acaaagattc agcccagagg gatgacatga tttttgaaga 500

 ttgtggcgat gtgcccagtg aaccgaaaga acgaggagac tttaatcatg 550

 aacgaggaga gcgaaaggtc tgcagattca agcttgaatg gctgggaaat 600

 tgctctggat taaatgatga aacttatggc tacaaagagg gcaaaccgtg 650

 cattattata aagctcaacc gagttctagg cttcaaacct aagcctccca 700

 agaatgagtc cttggagact tacccagtga tgaagtataa cccaaatgtc 750

 cttcccgttc agtgcactgg caagcgagat gaagataagg ataaagttgg 800

 aaatgtggag tattttggac tgggcaactc ccctggtttt cctctgcagt 850

 attatccgta ctatggcaaa ctcctgcagc ccaaatacct gcagcccctg 900

 ctggccgtac agttcaccaa tcttaccatg gacactgaaa ttcgcataga 950

 gtgtaaggcg tacggtgaga acattgggta cagtgagaaa gaccgttttc 1000

 agggacgttt tgatgtaaaa attgaagtta agagctgatc acaagcacaa 1050

 atctttccca ctagccattt aataagttaa aaaaagatac aaaaacaaaa 1100

 acctactagt cttgaacaaa ctgtcatacg tatgggacct acacttaatc 1150

 tatatgcttt acactagctt tctgcattta ataggttaga atgtaaatta 1200

 aagtgtagca atagcaacaa aatatttatt ctactgtaaa tgacaaaaga 1250

 aaaagaaaaa ttgagccttg ggacgtgccc atttttactg taaattatga 1300

 ttccgtaact gaccttgtag taagcagtgt ttctggcccc taagtattgc 1350

 tgccttgtgt attttattta gtgtacagta ctacaggtgc atactctggt 1400

 catttttcaa gccatgtttt attgtatctg ttttctactt tatgtgagca 1450

 aggtttgctg tccaaggtgt aaatattcaa cgggaataaa actggcatgg 1500

 taattttttt tttttgtttg ttttttgttt tttggctctt tcaaaggtaa 1550

 tggcccatcg atgagcattt ttaacatact ccatagtctt ttcctgtggt 1600

 gttaggtctt tatttttatt tttttcctgg gggctggggt gggggtttgt 1650

 catgggggaa ctgcccttta aattttaagt gacactacag aaaaacacaa 1700

 aaaggtgatg ggttgtgtta tgcttgtatt gaatgctgtc ttgacatctc 1750

 ttgccttgtc ctccggtatg ttctaaagct gtgtctgaga tctggatctg 1800

 cccatcactt tggcctaggg acagggctaa ttaatttgct ttatacattt 1850

 tcttttactt tccttttttc ctttctggag gcatcacatg ctggtgctgt 1900

 gtctttatga atgttttaac cattttcatg gtggaagaat tttatattta 1950

 tgcagttgta caattttatt tttttctgca agaaaaagtg taatgtatga 2000

 aataaaccaa agtcacttgt ttgaaaataa atctttattt tgaactttat 2050

 aaaagcaatg cagtacccca tagactggtg ttaaatgttg tctacagtgc 2100

 aaaatccatg ttctaacata tgtaataatt gccaggagta cagtgctctt 2150

 gttgatcttg tattcagtca ggttaaaaca acggacaata aaagaatgaa 2200

 ccgaattc 2208

<210> 250
<211> 303
<212> PRT
<213> Homo sapien

<400> 250
 Met Ala Arg Gly Lys Ala Lys Glu Glu Gly Ser Trp Lys Lys Phe
   1               5                  10                  15

 Ile Trp Asn Ser Glu Lys Lys Glu Phe Leu Gly Arg Thr Gly Gly
                  20                  25                  30

 Ser Trp Phe Lys Ile Leu Leu Phe Tyr Val Ile Phe Tyr Gly Cys
                  35                  40                  45

 Leu Ala Gly Ile Phe Ile Gly Thr Ile Gln Val Met Leu Leu Thr
                  50                  55                  60

 Ile Ser Glu Phe Lys Pro Thr Tyr Gln Asp Arg Val Ala Pro Pro
                  65                  70                  75

 Gly Leu Thr Gln Ile Pro Gln Ile Gln Lys Thr Glu Ile Ser Phe
                  80                  85                  90

 Arg Pro Asn Asp Pro Lys Ser Tyr Glu Ala Tyr Val Leu Asn Ile
                  95                 100                 105

 Val Arg Phe Leu Glu Lys Tyr Lys Asp Ser Ala Gln Arg Asp Asp
                 110                 115                 120

 Met Ile Phe Glu Asp Cys Gly Asp Val Pro Ser Glu Pro Lys Glu
                 125                 130                 135

 Arg Gly Asp Phe Asn His Glu Arg Gly Glu Arg Lys Val Cys Arg
                 140                 145                 150

 Phe Lys Leu Glu Trp Leu Gly Asn Cys Ser Gly Leu Asn Asp Glu
                 155                 160                 165

 Thr Tyr Gly Tyr Lys Glu Gly Lys Pro Cys Ile Ile Ile Lys Leu
                 170                 175                 180

 Asn Arg Val Leu Gly Phe Lys Pro Lys Pro Pro Lys Asn Glu Ser
                 185                 190                 195

 Leu Glu Thr Tyr Pro Val Met Lys Tyr Asn Pro Asn Val Leu Pro
                 200                 205                 210

 Val Gln Cys Thr Gly Lys Arg Asp Glu Asp Lys Asp Lys Val Gly
                 215                 220                 225

 Asn Val Glu Tyr Phe Gly Leu Gly Asn Ser Pro Gly Phe Pro Leu
                 230                 235                 240

 Gln Tyr Tyr Pro Tyr Tyr Gly Lys Leu Leu Gln Pro Lys Tyr Leu
                 245                 250                 255

 Gln Pro Leu Leu Ala Val Gln Phe Thr Asn Leu Thr Met Asp Thr
                 260                 265                 270

 Glu Ile Arg Ile Glu Cys Lys Ala Tyr Gly Glu Asn Ile Gly Tyr
                 275                 280                 285

 Ser Glu Lys Asp Arg Phe Gln Gly Arg Phe Asp Val Lys Ile Glu
                 290                 295                 300

 Val Lys Ser


<210> 251
<211> 2208
<212> DNA
<213> Homo sapien

<400> 251
 gaattcatgc taaattgctg gaaggctgcg tctctgctgt ggtgtcagtt 50

 ccggatgcct catcgccagg ggcgcgccgc agccacccac cctccggacc 100

 gcggcagctg ctgacccgcc atcgccatgg cccgcgggaa agccaaggag 150

 gagggcagct ggaagaaatt catctggaac tcagagaaga aggagtttct 200

 gggcaggacc ggtggcagtt ggtttaagat ccttctattc tacgtaatat 250

 tttatggctg cctggctggc atcttcatcg gaaccatcca agtgatgctg 300

 ctcaccatca gtgaatttaa gcccacatat caggaccgag tggccccgcc 350

 aggattaaca cagattcctc agatccagaa gactgaaatt tcctttcgtc 400

 ctaatgatcc caagagctat gaggcatatg tactgaacat agttaggttc 450

 ctggaaaagt acaaagattc agcccagagg gatgacatga tttttgaaga 500

 ttgtggcgat gtgcccagtg aaccgaaaga acgaggagac tttaatcatg 550

 aacgaggaga gcgaaaggtc tgcagattca agcttgaatg gctgggaaat 600

 tgctctggat taaatgatga aacttatggc tacaaagagg gcaaaccgtg 650

 cattattata aagctcaacc gagttctagg cttcaaacct aagcctccca 700

 agaatgagtc cttggagact tacccagtga tgaagtataa cccaaatgtc 750

 cttcccgttc agtgcactgg caagcgagat gaagataagg ataaagttgg 800

 aaatgtggag tattttggac tgggcaactc ccctggtttt cctctgcagt 850

 attatccgta ctatggcaaa ctcctgcagc ccaaatacct gcagcccctg 900

 ctggccgtac agttcaccaa tcttaccatg gacactgaaa ttcgcataga 950

 gtgtaaggcg tacggtgaga acattgggta cagtgagaaa gaccgttttc 1000

 agggacgttt tgatgtaaaa attgaagtta agagctgatc acaagcacaa 1050

 atctttccca ctagccattt aataagttaa aaaaagatac aaaaacaaaa 1100

 acctactagt cttgaacaaa ctgtcatacg tatgggacct acacttaatc 1150

 tatatgcttt acactagctt tctgcattta ataggttaga atgtaaatta 1200

 aagtgtagca atagcaacaa aatatttatt ctactgtaaa tgacaaaaga 1250

 aaaagaaaaa ttgagccttg ggacgtgccc atttttactg taaattatga 1300

 ttccgtaact gaccttgtag taagcagtgt ttctggcccc taagtattgc 1350

 tgccttgtgt attttattta gtgtacagta ctacaggtgc atactctggt 1400

 catttttcaa gccatgtttt attgtatctg ttttctactt tatgtgagca 1450

 aggtttgctg tccaaggtgt aaatattcaa cgggaataaa actggcatgg 1500

 taattttttt tttttgtttg ttttttgttt tttggctctt tcaaaggtaa 1550

 tggcccatcg atgagcattt ttaacatact ccatagtctt ttcctgtggt 1600

 gttaggtctt tatttttatt tttttcctgg gggctggggt gggggtttgt 1650

 catgggggaa ctgcccttta aattttaagt gacactacag aaaaacacaa 1700

 aaaggtgatg ggttgtgtta tgcttgtatt gaatgctgtc ttgacatctc 1750

 ttgccttgtc ctccggtatg ttctaaagct gtgtctgaga tctggatctg 1800

 cccatcactt tggcctaggg acagggctaa ttaatttgct ttatacattt 1850

 tcttttactt tccttttttc ctttctggag gcatcacatg ctggtgctgt 1900

 gtctttatga atgttttaac cattttcatg gtggaagaat tttatattta 1950

 tgcagttgta caattttatt tttttctgca agaaaaagtg taatgtatga 2000

 aataaaccaa agtcacttgt ttgaaaataa atctttattt tgaactttat 2050

 aaaagcaatg cagtacccca tagactggtg ttaaatgttg tctacagtgc 2100

 aaaatccatg ttctaacata tgtaataatt gccaggagta cagtgctctt 2150

 gttgatcttg tattcagtca ggttaaaaca acggacaata aaagaatgaa 2200

 ccgaattc 2208

<210> 252
<211> 303
<212> PRT
<213> Homo sapien

<400> 252
 Met Ala Arg Gly Lys Ala Lys Glu Glu Gly Ser Trp Lys Lys Phe
   1               5                  10                  15

 Ile Trp Asn Ser Glu Lys Lys Glu Phe Leu Gly Arg Thr Gly Gly
                  20                  25                  30

 Ser Trp Phe Lys Ile Leu Leu Phe Tyr Val Ile Phe Tyr Gly Cys
                  35                  40                  45

 Leu Ala Gly Ile Phe Ile Gly Thr Ile Gln Val Met Leu Leu Thr
                  50                  55                  60

 Ile Ser Glu Phe Lys Pro Thr Tyr Gln Asp Arg Val Ala Pro Pro
                  65                  70                  75

 Gly Leu Thr Gln Ile Pro Gln Ile Gln Lys Thr Glu Ile Ser Phe
                  80                  85                  90

 Arg Pro Asn Asp Pro Lys Ser Tyr Glu Ala Tyr Val Leu Asn Ile
                  95                 100                 105

 Val Arg Phe Leu Glu Lys Tyr Lys Asp Ser Ala Gln Arg Asp Asp
                 110                 115                 120

 Met Ile Phe Glu Asp Cys Gly Asp Val Pro Ser Glu Pro Lys Glu
                 125                 130                 135

 Arg Gly Asp Phe Asn His Glu Arg Gly Glu Arg Lys Val Cys Arg
                 140                 145                 150

 Phe Lys Leu Glu Trp Leu Gly Asn Cys Ser Gly Leu Asn Asp Glu
                 155                 160                 165

 Thr Tyr Gly Tyr Lys Glu Gly Lys Pro Cys Ile Ile Ile Lys Leu
                 170                 175                 180

 Asn Arg Val Leu Gly Phe Lys Pro Lys Pro Pro Lys Asn Glu Ser
                 185                 190                 195

 Leu Glu Thr Tyr Pro Val Met Lys Tyr Asn Pro Asn Val Leu Pro
                 200                 205                 210

 Val Gln Cys Thr Gly Lys Arg Asp Glu Asp Lys Asp Lys Val Gly
                 215                 220                 225

 Asn Val Glu Tyr Phe Gly Leu Gly Asn Ser Pro Gly Phe Pro Leu
                 230                 235                 240

 Gln Tyr Tyr Pro Tyr Tyr Gly Lys Leu Leu Gln Pro Lys Tyr Leu
                 245                 250                 255

 Gln Pro Leu Leu Ala Val Gln Phe Thr Asn Leu Thr Met Asp Thr
                 260                 265                 270

 Glu Ile Arg Ile Glu Cys Lys Ala Tyr Gly Glu Asn Ile Gly Tyr
                 275                 280                 285

 Ser Glu Lys Asp Arg Phe Gln Gly Arg Phe Asp Val Lys Ile Glu
                 290                 295                 300

 Val Lys Ser


<210> 253
<211> 2287
<212> DNA
<213> Homo sapien

<400> 253
 ggctgaggca gtggctcctt gcacagcagc tgcacgcgcc gtggctccgg 50

 atcttcttcg tctttgcagc gtagcccgag tcggtcagcg ccagaggacc 100

 tcagcagcca tgtcgaagcc ccatagtgaa gccgggactg ccttcattca 150

 gacccagcag ctgcacgcag ccatggctga cacattcctg gagcacatgt 200

 gccgcctgga cattgattca ccacccatca cagcccggaa cactggcatc 250

 atctgtacca ttggcccagc ttcccgatca gtggagacgt tgaaggagat 300

 gattaagtct ggaatgaatg tggctcgtct gaacttctct catggaactc 350

 atgagtacca tgcggagacc atcaagaatg tgcgcacagc cacggaaagc 400

 tttgcttctg accccatcct ctaccggccc gttgctgtgg ctctagacac 450

 taaaggacct gagatccgaa ctgggctcat caagggcagc ggcactgcag 500

 aggtggagct gaagaaggga gccactctca aaatcacgct ggataacgcc 550

 tacatggaaa agtgtgacga gaacatcctg tggctggact acaagaacat 600

 ctgcaaggtg gtggaagtgg gcagcaagat ctacgtggat gatgggctta 650

 tttctctcca ggtgaagcag aaaggtgccg acttcctggt gacggaggtg 700

 gaaaatggtg gctccttggg cagcaagaag ggtgtgaacc ttcctggggc 750

 tgctgtggac ttgcctgctg tgtcggagaa ggacatccag gatctgaagt 800

 ttggggtcga gcaggatgtt gatatggtgt ttgcgtcatt catccgcaag 850

 gcatctgatg tccatgaagt taggaaggtc ctgggagaga agggaaagaa 900

 catcaagatt atcagcaaaa tcgagaatca tgagggggtt cggaggtttg 950

 atgaaatcct ggaggccagt gatgggatca tggtggctcg tggtgatcta 1000

 ggcattgaga ttcctgcaga gaaggtcttc cttgctcaga agatgatgat 1050

 tggacggtgc aaccgagctg ggaagcctgt catctgtgct actcagatgc 1100

 tggagagcat gatcaagaag ccccgcccca ctcgggctga aggcagtgat 1150

 gtggccaatg cagtcctgga tggagccgac tgcatcatgc tgtctggaga 1200

 aacagccaaa ggggactatc ctctggaggc tgtgcgcatg cagaacctga 1250

 ttgcccgtga ggcagaggct gccatctacc acttgcaatt atttgaggaa 1300

 ctccgccgcc tggcgcccat taccagcgac cccacagaag ccaccgccgt 1350

 gggtgccgtg gaggcctcct tcaagtgctg cagtggggcc ataatcgtcc 1400

 tcaccaagtc tggcaggtct gctcaccagg tggccagata ccgcccacgt 1450

 gcccccatca ttgctgtgac ccggaatccc cagacagctc gtcaggccca 1500

 cctgtaccgt ggcatcttcc ctgtgctgtg caaggaccca gtccaggagg 1550

 cctgggctga ggacgtggac ctccgggtga actttgccat gaatgttggc 1600

 aaggcccgag gcttcttcaa gaagggagat gtggtcattg tgctgaccgg 1650

 atggcgccct ggctccggct tcaccaacac catgcgtgtt gttcctgtgc 1700

 cgtgatggac cccagagccc ctcctccagc ccctgtccca cccccttccc 1750

 ccagcccatc cattaggcca gcaacgcttg tagaactcac tctgggctgt 1800

 aacgtggcac tggtaggttg ggacaccagg gaagaagatc aacgcctcac 1850

 tgaaacatgg ctgtgtttgc agcctgctct agtgggacag cccagagcct 1900

 ggctgcccca tcatgtggcc ccacccaatc aagggaagaa ggaggaatgc 1950

 tggactggag gcccctggag ccagatggca agagggtgac agcttccttt 2000

 cctgtgtgta ctctgtccag ttcctttaga aaaaatggat gcccagagga 2050

 ctcccaaccc tggcttgggg tcaagaaaca gccagcaaga gttaggggcc 2100

 ttagggcact gggctgttgt tccattgaag ccgactctgg ccctggccct 2150

 tacttgcttc tctagctctc taggcctctc cagtttgcac ctgtccccac 2200

 cctccactca gctgtcctgc agcaaacact ccaccctcca ccttccattt 2250

 tcccccacta ctgcagcacc tccaggcctg ttgccgc 2287

<210> 254
<211> 531
<212> PRT
<213> Homo sapien

<400> 254
 Met Ser Lys Pro His Ser Glu Ala Gly Thr Ala Phe Ile Gln Thr
   1               5                  10                  15

 Gln Gln Leu His Ala Ala Met Ala Asp Thr Phe Leu Glu His Met
                  20                  25                  30

 Cys Arg Leu Asp Ile Asp Ser Pro Pro Ile Thr Ala Arg Asn Thr
                  35                  40                  45

 Gly Ile Ile Cys Thr Ile Gly Pro Ala Ser Arg Ser Val Glu Thr
                  50                  55                  60

 Leu Lys Glu Met Ile Lys Ser Gly Met Asn Val Ala Arg Leu Asn
                  65                  70                  75

 Phe Ser His Gly Thr His Glu Tyr His Ala Glu Thr Ile Lys Asn
                  80                  85                  90

 Val Arg Thr Ala Thr Glu Ser Phe Ala Ser Asp Pro Ile Leu Tyr
                  95                 100                 105

 Arg Pro Val Ala Val Ala Leu Asp Thr Lys Gly Pro Glu Ile Arg
                 110                 115                 120

 Thr Gly Leu Ile Lys Gly Ser Gly Thr Ala Glu Val Glu Leu Lys
                 125                 130                 135

 Lys Gly Ala Thr Leu Lys Ile Thr Leu Asp Asn Ala Tyr Met Glu
                 140                 145                 150

 Lys Cys Asp Glu Asn Ile Leu Trp Leu Asp Tyr Lys Asn Ile Cys
                 155                 160                 165

 Lys Val Val Glu Val Gly Ser Lys Ile Tyr Val Asp Asp Gly Leu
                 170                 175                 180

 Ile Ser Leu Gln Val Lys Gln Lys Gly Ala Asp Phe Leu Val Thr
                 185                 190                 195

 Glu Val Glu Asn Gly Gly Ser Leu Gly Ser Lys Lys Gly Val Asn
                 200                 205                 210

 Leu Pro Gly Ala Ala Val Asp Leu Pro Ala Val Ser Glu Lys Asp
                 215                 220                 225

 Ile Gln Asp Leu Lys Phe Gly Val Glu Gln Asp Val Asp Met Val
                 230                 235                 240

 Phe Ala Ser Phe Ile Arg Lys Ala Ser Asp Val His Glu Val Arg
                 245                 250                 255

 Lys Val Leu Gly Glu Lys Gly Lys Asn Ile Lys Ile Ile Ser Lys
                 260                 265                 270

 Ile Glu Asn His Glu Gly Val Arg Arg Phe Asp Glu Ile Leu Glu
                 275                 280                 285

 Ala Ser Asp Gly Ile Met Val Ala Arg Gly Asp Leu Gly Ile Glu
                 290                 295                 300

 Ile Pro Ala Glu Lys Val Phe Leu Ala Gln Lys Met Met Ile Gly
                 305                 310                 315

 Arg Cys Asn Arg Ala Gly Lys Pro Val Ile Cys Ala Thr Gln Met
                 320                 325                 330

 Leu Glu Ser Met Ile Lys Lys Pro Arg Pro Thr Arg Ala Glu Gly
                 335                 340                 345

 Ser Asp Val Ala Asn Ala Val Leu Asp Gly Ala Asp Cys Ile Met
                 350                 355                 360

 Leu Ser Gly Glu Thr Ala Lys Gly Asp Tyr Pro Leu Glu Ala Val
                 365                 370                 375

 Arg Met Gln Asn Leu Ile Ala Arg Glu Ala Glu Ala Ala Ile Tyr
                 380                 385                 390

 His Leu Gln Leu Phe Glu Glu Leu Arg Arg Leu Ala Pro Ile Thr
                 395                 400                 405

 Ser Asp Pro Thr Glu Ala Thr Ala Val Gly Ala Val Glu Ala Ser
                 410                 415                 420

 Phe Lys Cys Cys Ser Gly Ala Ile Ile Val Leu Thr Lys Ser Gly
                 425                 430                 435

 Arg Ser Ala His Gln Val Ala Arg Tyr Arg Pro Arg Ala Pro Ile
                 440                 445                 450

 Ile Ala Val Thr Arg Asn Pro Gln Thr Ala Arg Gln Ala His Leu
                 455                 460                 465

 Tyr Arg Gly Ile Phe Pro Val Leu Cys Lys Asp Pro Val Gln Glu
                 470                 475                 480

 Ala Trp Ala Glu Asp Val Asp Leu Arg Val Asn Phe Ala Met Asn
                 485                 490                 495

 Val Gly Lys Ala Arg Gly Phe Phe Lys Lys Gly Asp Val Val Ile
                 500                 505                 510

 Val Leu Thr Gly Trp Arg Pro Gly Ser Gly Phe Thr Asn Thr Met
                 515                 520                 525

 Arg Val Val Pro Val Pro
                 530

<210> 255
<211> 921
<212> DNA
<213> Homo sapien

<400> 255
 cgcgactccc acttccgccc ttttggctct ctgaccagca ccatggcggt 50

 tggcaagaac aagcgcctta cgaaaggcgg caaaaaggga gccaagaaga 100

 aagtggttga tccattttct aagaaagatt ggtatgatgt gaaagcacct 150

 gctatgttca atataagaaa tattggaaag acgctcgtca ccaggaccca 200

 aggaaccaaa attgcatctg atggtctcaa gggtcgtgtg tttgaagtga 250

 gtcttgctga tttgcagaat gatgaagttg catttagaaa attcaagctg 300

 attactgaag atgttcaggg taaaaactgc ctgactaact tccatggcat 350

 ggatcttacc cgtgacaaaa tgtgttccat ggtcaaaaaa tggcagacaa 400

 tgattgaagc tcacgttgat gtcaagacta ccgatggtta cttgcttcgt 450

 ctgttctgtg ttggttttac taaaaaacgc aacaatcaga tacggaagac 500

 ctcttatgct cagcaccaac aggtccgcca aatccggaag aagatgatgg 550

 aaatcatgac ccgagaggtg cagacaaatg acttgaaaga agtggtcaat 600

 aaattgattc cagacagcat tggaaaagac atagaaaagg cttgccaatc 650

 tatttatcct ctccatgatg tcttcgttag aaaagtaaaa atgctgaaga 700

 agcccaagtt tgaattggga aagctcatgg agcttcatgg tgaaggcagt 750

 agttctggaa aagccactgg ggacgagaca ggtgctaaag ttgaacgagc 800

 tgatggatat gaaccaccag tccaagaatc tgtttaaagt tcagacttca 850

 aatagtggca aataaaaagt gctatttgtg atggtttgct tctgaaaaaa 900

 aaaaaaaaaa aaaaaaaaaa a 921

<210> 256
<211> 264
<212> PRT
<213> Homo sapien

<400> 256
 Met Ala Val Gly Lys Asn Lys Arg Leu Thr Lys Gly Gly Lys Lys
   1               5                  10                  15

 Gly Ala Lys Lys Lys Val Val Asp Pro Phe Ser Lys Lys Asp Trp
                  20                  25                  30

 Tyr Asp Val Lys Ala Pro Ala Met Phe Asn Ile Arg Asn Ile Gly
                  35                  40                  45

 Lys Thr Leu Val Thr Arg Thr Gln Gly Thr Lys Ile Ala Ser Asp
                  50                  55                  60

 Gly Leu Lys Gly Arg Val Phe Glu Val Ser Leu Ala Asp Leu Gln
                  65                  70                  75

 Asn Asp Glu Val Ala Phe Arg Lys Phe Lys Leu Ile Thr Glu Asp
                  80                  85                  90

 Val Gln Gly Lys Asn Cys Leu Thr Asn Phe His Gly Met Asp Leu
                  95                 100                 105

 Thr Arg Asp Lys Met Cys Ser Met Val Lys Lys Trp Gln Thr Met
                 110                 115                 120

 Ile Glu Ala His Val Asp Val Lys Thr Thr Asp Gly Tyr Leu Leu
                 125                 130                 135

 Arg Leu Phe Cys Val Gly Phe Thr Lys Lys Arg Asn Asn Gln Ile
                 140                 145                 150

 Arg Lys Thr Ser Tyr Ala Gln His Gln Gln Val Arg Gln Ile Arg
                 155                 160                 165

 Lys Lys Met Met Glu Ile Met Thr Arg Glu Val Gln Thr Asn Asp
                 170                 175                 180

 Leu Lys Glu Val Val Asn Lys Leu Ile Pro Asp Ser Ile Gly Lys
                 185                 190                 195

 Asp Ile Glu Lys Ala Cys Gln Ser Ile Tyr Pro Leu His Asp Val
                 200                 205                 210

 Phe Val Arg Lys Val Lys Met Leu Lys Lys Pro Lys Phe Glu Leu
                 215                 220                 225

 Gly Lys Leu Met Glu Leu His Gly Glu Gly Ser Ser Ser Gly Lys
                 230                 235                 240

 Ala Thr Gly Asp Glu Thr Gly Ala Lys Val Glu Arg Ala Asp Gly
                 245                 250                 255

 Tyr Glu Pro Pro Val Gln Glu Ser Val
                 260

<210> 257
<211> 2130
<212> DNA
<213> Homo sapien

<400> 257
 tgaaccgagg caagggggcg cggcgcacgc agtatggcgc ccaacatcta 50

 cttggttcgc cagcggatca gtcgactcgg ccagaggatg tccggcttcc 100

 agatcaacct caacccgctc aaggagccac tcggcttcat caaggtcctc 150

 gagtggattg cttctatctt tgcttttgcc acctgtggag gttttaaggg 200

 ccaaacagaa attcaagtga attgtcctcc tgcagttact gagaataaaa 250

 ctgttacagc tacttttggt tatccattca ggttgaatga ggcatcattt 300

 cagccacctc caggtgtaaa catatgtgat gtaaattgga aagattacgt 350

 cctcataggc gattactctt cttctgcaca attctatgtt acctttgcag 400

 tctttgtgtt cctgtactgc attgctgccc ttctgcttta tgttggctac 450

 acgagtctgt atctggatag tcgtaaactt cctatgatag actttgttgt 500

 tacacttgtt gccacttttt tgtggttggt gagcacttca gcctgggcta 550

 aagctctgac agatattaaa atagctactg gtcacaatat tattgatgaa 600

 cttccgcctt gtaagaagaa agcagtactg tgttactttg gctctgtgac 650

 cagtatggga tccctaaatg tatctgtgat atttggcttt ctaaatatga 700

 tactctgggg aggaaatgct tggtttgtgt acaaggagac cagcctacac 750

 agtccatcaa atacatctgc ccctcatagc caaggaggta ttccacctcc 800

 taccggaata taattaaagg gagaaataca ctgtatgaag tatatgttga 850

 tactatgaca tgttgccaac accttgagaa gcattatttg tttctaataa 900

 aagtaatggc tttgtcaata tattggtggg tttaaaactt tgctgctttt 950

 ttacataaag cctgtgcctt tcctagaaag ttaagatgta aatgtattct 1000

 cacatgtaaa tttgaaagtt caggggtcta ttatgaaatg gattacacat 1050

 tttaaatgaa cccataattt ttttcactaa agctgtttgc cctccaaagt 1100

 gtttacacct aagcctaaca tgtatcgctc attcagaaaa ctgttatatt 1150

 gtcataccat agtaggaaga aaaaccttta tttggaatat acactactgt 1200

 aagtttgtac agatcatata cctaccacct gtctttgctt aaagagcctt 1250

 gattacataa atatgtagga aaaaacatat tgagttcaaa atttatatct 1300

 aacattgttt atgttatgat tttttttaat tgcaaagact aggtgtatat 1350

 ttttttctgt ttttctaaat gacccgtggt acttaatagg tgtactaaaa 1400

 ttgtgttggg agcagggatt tggaaatttc tgagagatgt gtagttaatt 1450

 agtaattctg tttcatgaga tatgatctgt tatgctagtg gtttaatagg 1500

 cttgctatgt aagtagaacg tggctcaact agatatctta tatgtatggg 1550

 cattacctct tagtgatatt tgtttcctgt cctttgttgc tcatgctgtt 1600

 taagtgcagg ctgagaccca gcctctttgt aagtacagta aaataatcca 1650

 ccgtttttta cagaccctag tcaaagggtt aaaaaaatta agattgcttt 1700

 ccatgtttga aatttaccat tgagagtcaa tgaagttgct attttgagtt 1750

 tagcattgat attgtgaaaa taagtgcaat ttggatttca tgtttcttaa 1800

 tattcattct tgtttcacaa atgaatgatt aaggaattat gcatcataaa 1850

 ggaacctaag tgaggtatat gatgagtgta ttgtctttgc acacacatat 1900

 aggtatattc tgaatacaag cttattcatt ttgcttccta atctttttgt 1950

 tgtacaggga ttcaggtttc ttattcttac aacatgattg tttatatgtg 2000

 aagcacatct tgctgttgcc ttatttttga tgcttttatt catgacaaga 2050

 attgtcaata taagaatgta tatctttgcc gcaaccaatt taataaagga 2100

 gttgaaagaa aaaaaaaaaa aaaaaaaaaa 2130

<210> 258
<211> 259
<212> PRT
<213> Homo sapien

<400> 258
 Met Ala Pro Asn Ile Tyr Leu Val Arg Gln Arg Ile Ser Arg Leu
   1               5                  10                  15

 Gly Gln Arg Met Ser Gly Phe Gln Ile Asn Leu Asn Pro Leu Lys
                  20                  25                  30

 Glu Pro Leu Gly Phe Ile Lys Val Leu Glu Trp Ile Ala Ser Ile
                  35                  40                  45

 Phe Ala Phe Ala Thr Cys Gly Gly Phe Lys Gly Gln Thr Glu Ile
                  50                  55                  60

 Gln Val Asn Cys Pro Pro Ala Val Thr Glu Asn Lys Thr Val Thr
                  65                  70                  75

 Ala Thr Phe Gly Tyr Pro Phe Arg Leu Asn Glu Ala Ser Phe Gln
                  80                  85                  90

 Pro Pro Pro Gly Val Asn Ile Cys Asp Val Asn Trp Lys Asp Tyr
                  95                 100                 105

 Val Leu Ile Gly Asp Tyr Ser Ser Ser Ala Gln Phe Tyr Val Thr
                 110                 115                 120

 Phe Ala Val Phe Val Phe Leu Tyr Cys Ile Ala Ala Leu Leu Leu
                 125                 130                 135

 Tyr Val Gly Tyr Thr Ser Leu Tyr Leu Asp Ser Arg Lys Leu Pro
                 140                 145                 150

 Met Ile Asp Phe Val Val Thr Leu Val Ala Thr Phe Leu Trp Leu
                 155                 160                 165

 Val Ser Thr Ser Ala Trp Ala Lys Ala Leu Thr Asp Ile Lys Ile
                 170                 175                 180

 Ala Thr Gly His Asn Ile Ile Asp Glu Leu Pro Pro Cys Lys Lys
                 185                 190                 195

 Lys Ala Val Leu Cys Tyr Phe Gly Ser Val Thr Ser Met Gly Ser
                 200                 205                 210

 Leu Asn Val Ser Val Ile Phe Gly Phe Leu Asn Met Ile Leu Trp
                 215                 220                 225

 Gly Gly Asn Ala Trp Phe Val Tyr Lys Glu Thr Ser Leu His Ser
                 230                 235                 240

 Pro Ser Asn Thr Ser Ala Pro His Ser Gln Gly Gly Ile Pro Pro
                 245                 250                 255

 Pro Thr Gly Ile


<210> 259
<211> 2130
<212> DNA
<213> Homo sapien

<400> 259
 tgaaccgagg caagggggcg cggcgcacgc agtatggcgc ccaacatcta 50

 cttggttcgc cagcggatca gtcgactcgg ccagaggatg tccggcttcc 100

 agatcaacct caacccgctc aaggagccac tcggcttcat caaggtcctc 150

 gagtggattg cttctatctt tgcttttgcc acctgtggag gttttaaggg 200

 ccaaacagaa attcaagtga attgtcctcc tgcagttact gagaataaaa 250

 ctgttacagc tacttttggt tatccattca ggttgaatga ggcatcattt 300

 cagccacctc caggtgtaaa catatgtgat gtaaattgga aagattacgt 350

 cctcataggc gattactctt cttctgcaca attctatgtt acctttgcag 400

 tctttgtgtt cctgtactgc attgctgccc ttctgcttta tgttggctac 450

 acgagtctgt atctggatag tcgtaaactt cctatgatag actttgttgt 500

 tacacttgtt gccacttttt tgtggttggt gagcacttca gcctgggcta 550

 aagctctgac agatattaaa atagctactg gtcacaatat tattgatgaa 600

 cttccgcctt gtaagaagaa agcagtactg tgttactttg gctctgtgac 650

 cagtatggga tccctaaatg tatctgtgat atttggcttt ctaaatatga 700

 tactctgggg aggaaatgct tggtttgtgt acaaggagac cagcctacac 750

 agtccatcaa atacatctgc ccctcatagc caaggaggta ttccacctcc 800

 taccggaata taattaaagg gagaaataca ctgtatgaag tatatgttga 850

 tactatgaca tgttgccaac accttgagaa gcattatttg tttctaataa 900

 aagtaatggc tttgtcaata tattggtggg tttaaaactt tgctgctttt 950

 ttacataaag cctgtgcctt tcctagaaag ttaagatgta aatgtattct 1000

 cacatgtaaa tttgaaagtt caggggtcta ttatgaaatg gattacacat 1050

 tttaaatgaa cccataattt ttttcactaa agctgtttgc cctccaaagt 1100

 gtttacacct aagcctaaca tgtatcgctc attcagaaaa ctgttatatt 1150

 gtcataccat agtaggaaga aaaaccttta tttggaatat acactactgt 1200

 aagtttgtac agatcatata cctaccacct gtctttgctt aaagagcctt 1250

 gattacataa atatgtagga aaaaacatat tgagttcaaa atttatatct 1300

 aacattgttt atgttatgat tttttttaat tgcaaagact aggtgtatat 1350

 ttttttctgt ttttctaaat gacccgtggt acttaatagg tgtactaaaa 1400

 ttgtgttggg agcagggatt tggaaatttc tgagagatgt gtagttaatt 1450

 agtaattctg tttcatgaga tatgatctgt tatgctagtg gtttaatagg 1500

 cttgctatgt aagtagaacg tggctcaact agatatctta tatgtatggg 1550

 cattacctct tagtgatatt tgtttcctgt cctttgttgc tcatgctgtt 1600

 taagtgcagg ctgagaccca gcctctttgt aagtacagta aaataatcca 1650

 ccgtttttta cagaccctag tcaaagggtt aaaaaaatta agattgcttt 1700

 ccatgtttga aatttaccat tgagagtcaa tgaagttgct attttgagtt 1750

 tagcattgat attgtgaaaa taagtgcaat ttggatttca tgtttcttaa 1800

 tattcattct tgtttcacaa atgaatgatt aaggaattat gcatcataaa 1850

 ggaacctaag tgaggtatat gatgagtgta ttgtctttgc acacacatat 1900

 aggtatattc tgaatacaag cttattcatt ttgcttccta atctttttgt 1950

 tgtacaggga ttcaggtttc ttattcttac aacatgattg tttatatgtg 2000

 aagcacatct tgctgttgcc ttatttttga tgcttttatt catgacaaga 2050

 attgtcaata taagaatgta tatctttgcc gcaaccaatt taataaagga 2100

 gttgaaagaa aaaaaaaaaa aaaaaaaaaa 2130

<210> 260
<211> 259
<212> PRT
<213> Homo sapien

<400> 260
 Met Ala Pro Asn Ile Tyr Leu Val Arg Gln Arg Ile Ser Arg Leu
   1               5                  10                  15

 Gly Gln Arg Met Ser Gly Phe Gln Ile Asn Leu Asn Pro Leu Lys
                  20                  25                  30

 Glu Pro Leu Gly Phe Ile Lys Val Leu Glu Trp Ile Ala Ser Ile
                  35                  40                  45

 Phe Ala Phe Ala Thr Cys Gly Gly Phe Lys Gly Gln Thr Glu Ile
                  50                  55                  60

 Gln Val Asn Cys Pro Pro Ala Val Thr Glu Asn Lys Thr Val Thr
                  65                  70                  75

 Ala Thr Phe Gly Tyr Pro Phe Arg Leu Asn Glu Ala Ser Phe Gln
                  80                  85                  90

 Pro Pro Pro Gly Val Asn Ile Cys Asp Val Asn Trp Lys Asp Tyr
                  95                 100                 105

 Val Leu Ile Gly Asp Tyr Ser Ser Ser Ala Gln Phe Tyr Val Thr
                 110                 115                 120

 Phe Ala Val Phe Val Phe Leu Tyr Cys Ile Ala Ala Leu Leu Leu
                 125                 130                 135

 Tyr Val Gly Tyr Thr Ser Leu Tyr Leu Asp Ser Arg Lys Leu Pro
                 140                 145                 150

 Met Ile Asp Phe Val Val Thr Leu Val Ala Thr Phe Leu Trp Leu
                 155                 160                 165

 Val Ser Thr Ser Ala Trp Ala Lys Ala Leu Thr Asp Ile Lys Ile
                 170                 175                 180

 Ala Thr Gly His Asn Ile Ile Asp Glu Leu Pro Pro Cys Lys Lys
                 185                 190                 195

 Lys Ala Val Leu Cys Tyr Phe Gly Ser Val Thr Ser Met Gly Ser
                 200                 205                 210

 Leu Asn Val Ser Val Ile Phe Gly Phe Leu Asn Met Ile Leu Trp
                 215                 220                 225

 Gly Gly Asn Ala Trp Phe Val Tyr Lys Glu Thr Ser Leu His Ser
                 230                 235                 240

 Pro Ser Asn Thr Ser Ala Pro His Ser Gln Gly Gly Ile Pro Pro
                 245                 250                 255

 Pro Thr Gly Ile


<210> 261
<211> 2644
<212> DNA
<213> Homo sapien

<400> 261
 ccgaggccaa gtcccgggcg ctagcccacc tcccacccgc ctcttggctc 50

 ctctcctcta ggccgtcgct ttcgggttct ctcatcgctt cgtcgttcgc 100

 caatgtttga ggagaaggcc agcagtcctt cagggaagat gggaggcgag 150

 gagaagccga ttggtgctgg tgaagagaag caaaaggaag gaggcaaaaa 200

 gaagaacaaa gaaggatctg gagatggagg tcgagctgag ttgaatcctt 250

 ggcctgaata tatttacaca cgtcttgaga tgtataatat actaaaagca 300

 gaacatgatt ccattctggc agaaaaggca gaaaaagata gcaagccaat 350

 taaagtcact ttgcctgatg gtaaacaggt tgatgcggaa tcttggaaaa 400

 ctacaccata tcaaattgcc tgtggaatta gtcaaggcct ggccgacaac 450

 accgttattg ctaaagtaaa taatgttgtg tgggacctgg accgccctct 500

 ggaagaagat tgtaccttgg agcttctcaa gtttgaggat gaggaagctc 550

 aggcagtgta ttggcactct agtgctcaca taatgggtga aggcatggaa 600

 agagtctatg gtggatgttt atgctacggt ccgccaatag aaaatggatt 650

 ctattatgac atgtacctcg aagaaggggg tgtgtctagc aatgatttct 700

 cttctctgga ggctttgtgt aagaaaatca ttaaagaaaa acaagctttt 750

 gaaagactgg aagttaagaa agaaacttta ctggcaatgt ttaagtacaa 800

 caagttcaaa tgccggatat tgaatgaaaa ggtgaatact ccaactacca 850

 cagtctatag atgtggccct ttgatagatc tctgccgggg tcctcatgtt 900

 agacacacgg gcaaaattaa ggctttaaaa atacacaaaa attcctccac 950

 gtactgggaa ggcaaagcag atatggagac tctccagaga atttatggca 1000

 tttcattccc agatcctaaa atgttgaaag agtgggagaa gttccaagag 1050

 gaagctaaaa accgagatca taggaaaatt ggcagggacc aagaactata 1100

 tttctttcat gaactcagcc ctggaagttg cttttttctg ccaaaaggag 1150

 tctatattta taatgcactt attgaattca ttaggagcga atataggaaa 1200

 agaggattcc aggaggtagt caccccaaac atcttcaaca gccgactctg 1250

 gatgacctcg ggccactggc agcactacag cgagaacatg ttctcctttg 1300

 aggtggagaa ggagctgttt gccctgaaac ccatgaactg cccaggacac 1350

 tcccttatgt ttgatcatcg gccaaggtcc tggcgagaac tgcctctgcg 1400

 gctagctgat tttgggggtc ttcataggaa cgagctgtct ggagcactca 1450

 caggactcac ccgggtacga agattccaac aggatgatgc tcacatattc 1500

 tgtgccatgg agcagattga agatgaaata aaaggttgtt tggattttct 1550

 acgtacggta tatagcgtat ttggattttc ttttaaacta aacctttcta 1600

 ctcgcccgga aaaattcctt ggagatatcg aagtatggga tcaagctgag 1650

 aaacaacttg aaaacagtct gaatgaattt ggtgaaaagt gggagttaaa 1700

 ctctggagat ggagctttct atggcccaaa gattgacata cagattaaag 1750

 atgcgattgg gcggtaccac cagtgtgcaa ccatccagct ggatttccag 1800

 ttgcccatca gatttaatct tacttatgta agccatgatg gtgaggataa 1850

 gaaaaggcca gtgattgttc atcgagccat cttgggatca gtggaaagaa 1900

 tgattgctat cctcacagaa aactatgggg gcaaattggc ccccttttgg 1950

 ctgtcccctc gccaggtaat ggtagttcca gtgggaccaa cctgtgatga 2000

 atatgcccaa aacgtacgac aacaattcca cgatgccaaa ttcatggcag 2050

 acattgatct ggatccaggc tgtacattga ataaaaagat tcgaaatgca 2100

 cagttagcac agtataactt cattttagtt gttggtgaaa aagagaaaat 2150

 cactggcact gttaatatcc gcacaagaga caataaggtc cacggggaac 2200

 gcaccatttc tgaaactatc gagcggctac agcagctcaa agagttccgc 2250

 agcaaacagg cagaagaaga attttaatga aaaaattacc cagattggct 2300

 ccatggaaaa ggaggaacag cgtttccgta aaattgactt tgtactcgaa 2350

 aacgtcaatt tatattgaac ttggaggagg agtttggcaa agtctgaaat 2400

 aggtcaacct gcaggcgtaa ctatttttga cctagtcagt ttttaaacaa 2450

 tgtgcatttg aaggagttaa ttaaaagaga gccaataaaa tgattttact 2500

 cattcagtat ctgagtactg gaagtgaaac atgaggaatg ctttagtgta 2550

 atgtgggaga acttttttgt aaatttaatg caattgaaaa agttttcaaa 2600

 ttcaattaag ataactagaa ttggttatgg tgtaacccga attc 2644

<210> 262
<211> 712
<212> PRT
<213> Homo sapien

<400> 262
 Met Gly Gly Glu Glu Lys Pro Ile Gly Ala Gly Glu Glu Lys Gln
   1               5                  10                  15

 Lys Glu Gly Gly Lys Lys Lys Asn Lys Glu Gly Ser Gly Asp Gly
                  20                  25                  30

 Gly Arg Ala Glu Leu Asn Pro Trp Pro Glu Tyr Ile Tyr Thr Arg
                  35                  40                  45

 Leu Glu Met Tyr Asn Ile Leu Lys Ala Glu His Asp Ser Ile Leu
                  50                  55                  60

 Ala Glu Lys Ala Glu Lys Asp Ser Lys Pro Ile Lys Val Thr Leu
                  65                  70                  75

 Pro Asp Gly Lys Gln Val Asp Ala Glu Ser Trp Lys Thr Thr Pro
                  80                  85                  90

 Tyr Gln Ile Ala Cys Gly Ile Ser Gln Gly Leu Ala Asp Asn Thr
                  95                 100                 105

 Val Ile Ala Lys Val Asn Asn Val Val Trp Asp Leu Asp Arg Pro
                 110                 115                 120

 Leu Glu Glu Asp Cys Thr Leu Glu Leu Leu Lys Phe Glu Asp Glu
                 125                 130                 135

 Glu Ala Gln Ala Val Tyr Trp His Ser Ser Ala His Ile Met Gly
                 140                 145                 150

 Glu Gly Met Glu Arg Val Tyr Gly Gly Cys Leu Cys Tyr Gly Pro
                 155                 160                 165

 Pro Ile Glu Asn Gly Phe Tyr Tyr Asp Met Tyr Leu Glu Glu Gly
                 170                 175                 180

 Gly Val Ser Ser Asn Asp Phe Ser Ser Leu Glu Ala Leu Cys Lys
                 185                 190                 195

 Lys Ile Ile Lys Glu Lys Gln Ala Phe Glu Arg Leu Glu Val Lys
                 200                 205                 210

 Lys Glu Thr Leu Leu Ala Met Phe Lys Tyr Asn Lys Phe Lys Cys
                 215                 220                 225

 Arg Ile Leu Asn Glu Lys Val Asn Thr Pro Thr Thr Thr Val Tyr
                 230                 235                 240

 Arg Cys Gly Pro Leu Ile Asp Leu Cys Arg Gly Pro His Val Arg
                 245                 250                 255

 His Thr Gly Lys Ile Lys Ala Leu Lys Ile His Lys Asn Ser Ser
                 260                 265                 270

 Thr Tyr Trp Glu Gly Lys Ala Asp Met Glu Thr Leu Gln Arg Ile
                 275                 280                 285

 Tyr Gly Ile Ser Phe Pro Asp Pro Lys Met Leu Lys Glu Trp Glu
                 290                 295                 300

 Lys Phe Gln Glu Glu Ala Lys Asn Arg Asp His Arg Lys Ile Gly
                 305                 310                 315

 Arg Asp Gln Glu Leu Tyr Phe Phe His Glu Leu Ser Pro Gly Ser
                 320                 325                 330

 Cys Phe Phe Leu Pro Lys Gly Val Tyr Ile Tyr Asn Ala Leu Ile
                 335                 340                 345

 Glu Phe Ile Arg Ser Glu Tyr Arg Lys Arg Gly Phe Gln Glu Val
                 350                 355                 360

 Val Thr Pro Asn Ile Phe Asn Ser Arg Leu Trp Met Thr Ser Gly
                 365                 370                 375

 His Trp Gln His Tyr Ser Glu Asn Met Phe Ser Phe Glu Val Glu
                 380                 385                 390

 Lys Glu Leu Phe Ala Leu Lys Pro Met Asn Cys Pro Gly His Ser
                 395                 400                 405

 Leu Met Phe Asp His Arg Pro Arg Ser Trp Arg Glu Leu Pro Leu
                 410                 415                 420

 Arg Leu Ala Asp Phe Gly Gly Leu His Arg Asn Glu Leu Ser Gly
                 425                 430                 435

 Ala Leu Thr Gly Leu Thr Arg Val Arg Arg Phe Gln Gln Asp Asp
                 440                 445                 450

 Ala His Ile Phe Cys Ala Met Glu Gln Ile Glu Asp Glu Ile Lys
                 455                 460                 465

 Gly Cys Leu Asp Phe Leu Arg Thr Val Tyr Ser Val Phe Gly Phe
                 470                 475                 480

 Ser Phe Lys Leu Asn Leu Ser Thr Arg Pro Glu Lys Phe Leu Gly
                 485                 490                 495

 Asp Ile Glu Val Trp Asp Gln Ala Glu Lys Gln Leu Glu Asn Ser
                 500                 505                 510

 Leu Asn Glu Phe Gly Glu Lys Trp Glu Leu Asn Ser Gly Asp Gly
                 515                 520                 525

 Ala Phe Tyr Gly Pro Lys Ile Asp Ile Gln Ile Lys Asp Ala Ile
                 530                 535                 540

 Gly Arg Tyr His Gln Cys Ala Thr Ile Gln Leu Asp Phe Gln Leu
                 545                 550                 555

 Pro Ile Arg Phe Asn Leu Thr Tyr Val Ser His Asp Gly Glu Asp
                 560                 565                 570

 Lys Lys Arg Pro Val Ile Val His Arg Ala Ile Leu Gly Ser Val
                 575                 580                 585

 Glu Arg Met Ile Ala Ile Leu Thr Glu Asn Tyr Gly Gly Lys Leu
                 590                 595                 600

 Ala Pro Phe Trp Leu Ser Pro Arg Gln Val Met Val Val Pro Val
                 605                 610                 615

 Gly Pro Thr Cys Asp Glu Tyr Ala Gln Asn Val Arg Gln Gln Phe
                 620                 625                 630

 His Asp Ala Lys Phe Met Ala Asp Ile Asp Leu Asp Pro Gly Cys
                 635                 640                 645

 Thr Leu Asn Lys Lys Ile Arg Asn Ala Gln Leu Ala Gln Tyr Asn
                 650                 655                 660

 Phe Ile Leu Val Val Gly Glu Lys Glu Lys Ile Thr Gly Thr Val
                 665                 670                 675

 Asn Ile Arg Thr Arg Asp Asn Lys Val His Gly Glu Arg Thr Ile
                 680                 685                 690

 Ser Glu Thr Ile Glu Arg Leu Gln Gln Leu Lys Glu Phe Arg Ser
                 695                 700                 705

 Lys Gln Ala Glu Glu Glu Phe
                 710

<210> 263
<211> 670
<212> DNA
<213> Homo sapien

<400> 263
 cggccacgag gcggaatccc ttctgctctc ccagcgcagc gccgccgccc 50

 ggcccctcca gcttcccgga ccatggccaa cctggagcgc accttcatcg 100

 ccatcaagcc ggacggcgtg cagcgcggcc tggtgggcga gatcatcaag 150

 cgcttcgagc agaagggatt ccgcctcgtg gccatgaagt tcctccgggc 200

 ctctgaagaa cacctgaagc agcactacat tgacctgaaa gaccgaccat 250

 tcttccctgg gctggtgaag tacatgaact cagggccggt tgtggccatg 300

 gtctgggagg ggctgaacgt ggtgaagaca ggccgagtga tgcttgggga 350

 gaccaatcca gcagattcaa agccaggcac cattcgtggg gacttctgca 400

 ttcaggttgg caggaacatc attcatggca gtgattcagt aaaaagtgct 450

 gaaaaagaaa tcagcctatg gtttaagcct gaagaactgg ttgactacaa 500

 gtcttgtgct catgactggg tctatgaata agaggtggac acaacagcag 550

 tctccttcag cacggcgtgg tgtgtccctg gacacagctc ttcattccat 600

 tgacttagag gcaacaggat tgatcattct tttatagagc atatttgcca 650

 ataaagcttt tggaagccgg 670

<210> 264
<211> 152
<212> PRT
<213> Homo sapien

<400> 264
 Met Ala Asn Leu Glu Arg Thr Phe Ile Ala Ile Lys Pro Asp Gly
   1               5                  10                  15

 Val Gln Arg Gly Leu Val Gly Glu Ile Ile Lys Arg Phe Glu Gln
                  20                  25                  30

 Lys Gly Phe Arg Leu Val Ala Met Lys Phe Leu Arg Ala Ser Glu
                  35                  40                  45

 Glu His Leu Lys Gln His Tyr Ile Asp Leu Lys Asp Arg Pro Phe
                  50                  55                  60

 Phe Pro Gly Leu Val Lys Tyr Met Asn Ser Gly Pro Val Val Ala
                  65                  70                  75

 Met Val Trp Glu Gly Leu Asn Val Val Lys Thr Gly Arg Val Met
                  80                  85                  90

 Leu Gly Glu Thr Asn Pro Ala Asp Ser Lys Pro Gly Thr Ile Arg
                  95                 100                 105

 Gly Asp Phe Cys Ile Gln Val Gly Arg Asn Ile Ile His Gly Ser
                 110                 115                 120

 Asp Ser Val Lys Ser Ala Glu Lys Glu Ile Ser Leu Trp Phe Lys
                 125                 130                 135

 Pro Glu Glu Leu Val Asp Tyr Lys Ser Cys Ala His Asp Trp Val
                 140                 145                 150

 Tyr Glu


<210> 265
<211> 2493
<212> DNA
<213> Homo sapien

<400> 265
 aactgagggg gtggctagca gcaaacaagt atggagctag cacaagagct 50

 aagaaataac ctccatccct accactcagc acacaacccc tacggtccca 100

 gcacactgag ccctggctcc caagggctgc ctcctgacag ctccgtcatg 150

 gcacttttta acgcttcagc aacaaacacc aggcagctgt tgccactggc 200

 ctcctacccc tactctgggg cttgggggtc actcccccca ggacttacct 250

 tccaaaacaa actttcttca ctttgtatta taggtacaag acagcgactt 300

 acgtatcttt tctcctcctc cctagtgttc ctccccattt tttcagaaaa 350

 cacttctgac tcctgtccct tccccttctg cttttggtca gtccctgttc 400

 ttgagcctct tttctcctct ccccaggatg cagaaagtgg tgaacccagg 450

 aactgaggaa ggaggtttcc agttcattta cattaagggc cctgggggag 500

 aataaagctc agagcaggag ggagtaagga aacatttcct ttttgttttt 550

 atttggttgg agtttctcat atttgaaaac attgcggtat ccatgatttg 600

 gccttgtgga gggtgttcct aggtagaggt gagaatgggg aggcaagatc 650

 tcaggcacca ggcaggaggt gccttgtaag ctaactgggc ggaggtggag 700

 gtgcagtgtc aactgtggct ctgtaactct tcaaaggccc agtttcccct 750

 cacgcagcct cttaggtagc gtttccccta atcgtggggg ttggacccca 800

 gagtcttcca aagaattttc actggttgcc tgcatctttg gctctgctgt 850

 gatctgattg gaggagggac agtttctggt acccatcctc tgatttatac 900

 atatgcattt tttcccctct ggcctttaga tggcctcagc cccagccacc 950

 atatacccct gcagtttgca ctttaattga tggtagttca gttggggtac 1000

 ttgttttatg gaagttttga ttgatttact tgccctccca ccttcttttt 1050

 aattcaatga aatctgaggt taatgcgagg ttcgaggaga ggttatagat 1100

 aaaactacca gtggcagcta ctcaagtcct atctccactg ttagcttcct 1150

 ccaactctaa ttattaacct atattcttgc caagctaact attgactata 1200

 ggtttgcctt tcctggagaa ttaattgagc aattgaggag tgtctcagga 1250

 tagcacaggc caaggtaggg gagtaaaaag gaggtcaggc aaaagggagg 1300

 agttttctgt cctttcccag gtttcacact caatttgata tccattacca 1350

 tgtcttttct acttccttgt aaataggtat gatctttatt cccactgtac 1400

 agtctgttct atcctctgcc tcccatcagg ccctgtttct ttgttccttt 1450

 gttaatatct tgaatttagt ccctccatcc ttaatccccc catccctccc 1500

 catcatgcaa ccagtggttt aatccatgta ccaatagggg ctagtaccac 1550

 agaggcctcc tgtggtgccc tcgtatcata ccacctgttc ctgtggagag 1600

 ggaatgaccg gcactgaagg taccttacaa ctggctcata ttatcagagg 1650

 accttggtcc tttctaaatc tctagtctct cttcatatcc ttcatcaggt 1700

 gttttaagat gtctctgaga agccatcaag gcaaaagaga actttaagtt 1750

 ccttgttcca gcccggagtt ttgggaaaga aagaaaggaa aggtcacagt 1800

 gacctaggat tggaaccttc ctgccctttt ggcttgcaga ctgccttcta 1850

 tcccagaaca gctgagaaat ctatgaagct gagattctga aggacccagc 1900

 ttaggttctt ccacttaagg cctcaattcc cttccttttc caaggggcag 1950

 ccttagttcc catggccctg aaacacacac atttccccct tcctttccca 2000

 gaagccactg gccccccata gcacccagtg catccttttt acaagtggaa 2050

 gaactaggat ggctttccaa agtcttctag aaatgaagtt ctttctctgt 2100

 gcagctttcc cccttggagc aggagtgaag atgtttcatt atcttgggcc 2150

 tgggaaacca cttccccagg cttctccctc cccccacccc cataggaaca 2200

 ggatttggcc ttagcttcgt gggcctatcg gctgccttcc ctctacttcc 2250

 taccacctct tctgccttcc tttgagctct gttgggcttg gggatcttag 2300

 ttttcttttg tttatttccc agctcatttt tttcttctgg tcagtttttt 2350

 taaggggggg tgttgtggtt ttttgttttt gttttgcttc tgagaaagca 2400

 tttgcctttc ttcctctccc aacataacaa tcgtggtaac agaatgcgac 2450

 tgctgattta ccgatgtatt taatgtaagt aaaaaaagga aaa 2493

<210> 266
<211> 141
<212> PRT
<213> Homo sapien

<400> 266
 Met Glu Leu Ala Gln Glu Leu Arg Asn Asn Leu His Pro Tyr His
   1               5                  10                  15

 Ser Ala His Asn Pro Tyr Gly Pro Ser Thr Leu Ser Pro Gly Ser
                  20                  25                  30

 Gln Gly Leu Pro Pro Asp Ser Ser Val Met Ala Leu Phe Asn Ala
                  35                  40                  45

 Ser Ala Thr Asn Thr Arg Gln Leu Leu Pro Leu Ala Ser Tyr Pro
                  50                  55                  60

 Tyr Ser Gly Ala Trp Gly Ser Leu Pro Pro Gly Leu Thr Phe Gln
                  65                  70                  75

 Asn Lys Leu Ser Ser Leu Cys Ile Ile Gly Thr Arg Gln Arg Leu
                  80                  85                  90

 Thr Tyr Leu Phe Ser Ser Ser Leu Val Phe Leu Pro Ile Phe Ser
                  95                 100                 105

 Glu Asn Thr Ser Asp Ser Cys Pro Phe Pro Phe Cys Phe Trp Ser
                 110                 115                 120

 Val Pro Val Leu Glu Pro Leu Phe Ser Ser Pro Gln Asp Ala Glu
                 125                 130                 135

 Ser Gly Glu Pro Arg Asn
                 140

<210> 267
<211> 1793
<212> DNA
<213> Homo sapien

<400> 267
 ggcaccgcgc gggacggagc ttggctgttg gtcggtgggt tcccgtgcgg 50

 cggcggccaa ggaggaggag acacagttgg agcagctccg tgggctgact 100

 ggggcgaggc ctcagcagcg cgagcttgag tgcggccgag cctgcggcgc 150

 cttcccctgc gggtggggac gagcgggccc cgcggcgtca tcggcggcga 200

 ggagccgccg cgcctcggcc tagcatgtcg gaagcgggcg aggagcagcc 250

 catggagacg acgggcgcca ccgagaacgg acatgaggcc gtccccgaag 300

 cgagtcgcgg ccggggctgg acgggcgccg cggcggggct ggaggcgcga 350

 ccgccgcgcc cccgagcggg aatcagaacg gcgccgaggg accagatcaa 400

 cgccagcaag aacgaggagg acgcgggaaa aatgttcgtt ggtggcctga 450

 gctgggatac tagcaaaaaa gatttaaaag actattttac taaatttgga 500

 gaggtcgttg actgtacaat aaaaatggat cccaacactg gacggtcaag 550

 agggtttggg tttatcctgt tcaaagatgc agccagtgtg gagaaggtcc 600

 tagaccagaa ggagcacagg ctggatggcc gtgtcattga ccctaaaaag 650

 gccatggcta tgaagaagga cccggtcaag aaaatcttcg ttgggggtct 700

 gaatcctgaa agtcccactg aggaaaagat cagggagtac tttggcgagt 750

 ttggggagat tgaggccatt gaattgccaa tggatccaaa gttgaacaaa 800

 agacgaggtt ttgtgtttat cacctttaaa gaagaagaac ccgtgaagaa 850

 ggttctggag aaaaagttcc atactgtcag tggaagcaag tgtgagatca 900

 aggtggccca gcccaaagaa gtctatcagc agcagcagta tggctctggg 950

 ggccgtggaa accgcaaccg agggaaccga ggcagcggag gtggtggtgg 1000

 aggtggaggt cagagtcaga gttggaatca gggctacggc aactactgga 1050

 accagggcta cggctaccag cagggctacg ggcctggcta tggcggctac 1100

 gactactcgc cctatggcta ttacggctac ggccccggct acgactacag 1150

 tcagggtagt acaaactacg gcaagagcca gcgacgtggt ggccatcaga 1200

 ataactacaa gccatactga ggcggccaag ggagcgacca actgatcgca 1250

 cacatgcttt gtttggatat ggagtgaaca caattatgta ccaaatttaa 1300

 cttggcaaac tttctattgc ctgtcccatg tgcatcttat ttaaaatttc 1350

 ccccatggaa atcactctcc tgttgactat ttccagagct ctaggtgttt 1400

 aggcagcgtg tggtgtctga gaggccatag cgccatcatg ggctgatttt 1450

 tattaccagg tcccccagaa gcaggtgaga ggctctgctt cctgctgccg 1500

 ctctgcagcc tggacctgtg gaccctggtt gtaaagagta aattgtatct 1550

 taggaaacca gtgtcacctt tttttcacct tttaatttta tattatttgc 1600

 gtcatacatt tcctgtaacg gaagtgttaa ttttactgta ctttttggta 1650

 ccccttttgg gaatctaatg tattgtaagg tattttacac gtgtcctgat 1700

 tttgccacaa cctggatatt gaagctatcc aagcttttga aataaaattt 1750

 aaaaacccca agcctgggtg agtgtgggaa aaaaaaaaaa aaa 1793

<210> 268
<211> 331
<212> PRT
<213> Homo sapien

<400> 268
 Met Ser Glu Ala Gly Glu Glu Gln Pro Met Glu Thr Thr Gly Ala
   1               5                  10                  15

 Thr Glu Asn Gly His Glu Ala Val Pro Glu Ala Ser Arg Gly Arg
                  20                  25                  30

 Gly Trp Thr Gly Ala Ala Ala Gly Leu Glu Ala Arg Pro Pro Arg
                  35                  40                  45

 Pro Arg Ala Gly Ile Arg Thr Ala Pro Arg Asp Gln Ile Asn Ala
                  50                  55                  60

 Ser Lys Asn Glu Glu Asp Ala Gly Lys Met Phe Val Gly Gly Leu
                  65                  70                  75

 Ser Trp Asp Thr Ser Lys Lys Asp Leu Lys Asp Tyr Phe Thr Lys
                  80                  85                  90

 Phe Gly Glu Val Val Asp Cys Thr Ile Lys Met Asp Pro Asn Thr
                  95                 100                 105

 Gly Arg Ser Arg Gly Phe Gly Phe Ile Leu Phe Lys Asp Ala Ala
                 110                 115                 120

 Ser Val Glu Lys Val Leu Asp Gln Lys Glu His Arg Leu Asp Gly
                 125                 130                 135

 Arg Val Ile Asp Pro Lys Lys Ala Met Ala Met Lys Lys Asp Pro
                 140                 145                 150

 Val Lys Lys Ile Phe Val Gly Gly Leu Asn Pro Glu Ser Pro Thr
                 155                 160                 165

 Glu Glu Lys Ile Arg Glu Tyr Phe Gly Glu Phe Gly Glu Ile Glu
                 170                 175                 180

 Ala Ile Glu Leu Pro Met Asp Pro Lys Leu Asn Lys Arg Arg Gly
                 185                 190                 195

 Phe Val Phe Ile Thr Phe Lys Glu Glu Glu Pro Val Lys Lys Val
                 200                 205                 210

 Leu Glu Lys Lys Phe His Thr Val Ser Gly Ser Lys Cys Glu Ile
                 215                 220                 225

 Lys Val Ala Gln Pro Lys Glu Val Tyr Gln Gln Gln Gln Tyr Gly
                 230                 235                 240

 Ser Gly Gly Arg Gly Asn Arg Asn Arg Gly Asn Arg Gly Ser Gly
                 245                 250                 255

 Gly Gly Gly Gly Gly Gly Gly Gln Ser Gln Ser Trp Asn Gln Gly
                 260                 265                 270

 Tyr Gly Asn Tyr Trp Asn Gln Gly Tyr Gly Tyr Gln Gln Gly Tyr
                 275                 280                 285

 Gly Pro Gly Tyr Gly Gly Tyr Asp Tyr Ser Pro Tyr Gly Tyr Tyr
                 290                 295                 300

 Gly Tyr Gly Pro Gly Tyr Asp Tyr Ser Gln Gly Ser Thr Asn Tyr
                 305                 310                 315

 Gly Lys Ser Gln Arg Arg Gly Gly His Gln Asn Asn Tyr Lys Pro
                 320                 325                 330

 Tyr


<210> 269
<211> 3116
<212> DNA
<213> Homo sapien

<400> 269
 agcgctcaga tacgcgacgc gtagcaggcg gggaccgaac gggtgcctca 50

 gtgtccttcc cctcccctcg cctggcctcg ccgtcctctc cccgcagccg 100

 gaccggaact atgtgatccc ggaagttccg gggcctttgc tgtgtgggat 150

 aaacagtaat ggcggaggct gcaactcccg gaacaacagc cacaacatca 200

 ggagcaggag cggcagcggc gacggcggca gcagcctccc ccaccccgat 250

 ccccacagtc accgccccgt ccctgggggc gggcggaggg ggcggcggca 300

 gcgacggcag cggcggcggc tggactaaac aggtcacctg caggtatttt 350

 atgcatgggg tttgtaagga aggagacaac tgtcgctact cgcatgacct 400

 ctctgacagt ccgtatagtg tagtgtgcaa gtattttcag cgagggtact 450

 gtatttatgg agaccgctgc agatatgaac atagcaaacc attgaaacag 500

 gaagaagcaa ctgctacaga gctaactaca aagtcatccc ttgctgcttc 550

 ctcaagtctc tcatcgatag ttggaccact tgttgaaatg aatacaggcg 600

 aagctgagtc aagaaattca aactttgcaa ctgtaggagc aggttcagag 650

 gactgggtga atgctattga gtttgttcct gggcaaccct actgtggccg 700

 tactgcgcct tcctgcactg aagcacccct gcagggctca gtgaccaagg 750

 aagaatcaga gaaagagcaa accgccgtgg agacaaagaa gcagctgtgc 800

 ccctatgctg cagtgggaga gtgccgatac ggggagaact gtgtgtatct 850

 ccacggagat tcttgtgaca tgtgtgggct gcagctcctg catccaatgg 900

 atgctgccca gagatcgcag catatcaaat cgtgcattga ggcccatgag 950

 aaggacatgg agctctcatt tgccgtgcag cgcagcaagg acatggtgtg 1000

 tgggatctgc atggaggtgg tctatgagaa agccaacccc agtgagcgcc 1050

 gcttcgggat cctctccaac tgcaaccaca cctactgtct caagtgcatt 1100

 cgcaagtgga ggagtgctaa gcaatttgag agcaagatca taaagtcctg 1150

 cccagaatgc cggatcacat ctaactttgt cattccaagt gagtactggg 1200

 tggaggagaa agaagagaag cagaaactca ttctgaaata caaggaggca 1250

 atgagcaaca aggcgtgcag gtattttgat gaaggacgtg ggagctgccc 1300

 atttggaggg aactgttttt acaagcatgc gtaccctgat ggccgtagag 1350

 aggagccaca gagacagaaa gtgggaacat caagcagata ccgggcccaa 1400

 cgaaggaacc acttctggga actcattgag gaaagagaga acagcaaccc 1450

 ctttgacaac gatgaagaag aggttgtcac ctttgagctg ggcgagatgt 1500

 tgcttatgct tttggctgca ggtggggacg acgaactaac agactctgaa 1550

 gatgagtggg acttgtttca tgatgagctg gaagattttt atgacttgga 1600

 tctatagcaa ccttgcgtgg cgtgtgaact ggtctgctga cctcagacag 1650

 cagctgtccc ctgtggtggt gtggcagtgc ctgtgttctc tcctaggcag 1700

 gcctctcaac tccaggtgct gtcctaagaa tttttaccca gggcctgtct 1750

 tctcaacccc tcacctttcc ctgaggagtg tgttgttttc cctgttgaaa 1800

 aaagttacaa aaataaatct taaagttagt tttttgtaac acgaatttaa 1850

 ctgtcagaca gttagtgtag gtgtgttgcg tcatctgttt tcaaccagat 1900

 tgcatttatg gacttttcac acactcattt tgaggacccc aggttcaaaa 1950

 gtaaaagcag tggccctgct ttggggtcca agaataggag tgatgggtga 2000

 agggacctaa gctggccaat agccctctgc cccagacatg ggatgtggat 2050

 ccttgaggtt tctggtgaaa tctgcacatc tgtgttttta tatctgttcc 2100

 ctaccctgta atccctacca cgtgcacttg ttctgtggtt ttggtctctt 2150

 gtttaattgc acacaagtaa tactactggg taaccagaat caggtgtgaa 2200

 tgtgttgaga ttttttactg ttttgcatga taggaaaatt gagaaagaat 2250

 acgtataaaa gatagagagg cataacatca atgcagagtt ggaagttggc 2300

 tcccaagggc tgacatggtg tgagtgtgtg ggtgtgtgat aagcttctca 2350

 tccctgcata gatgcagtat tcttagcctt agtagaaaaa cctggtttag 2400

 tggtttaagc cttgtgtggc agatagatct taaagggcaa agcagtatat 2450

 tggtagttgt caatatagca gtgctagctc tgtctatata aatagagaaa 2500

 tggggttagc catagaggtt aaaactacct ggttatccca tataataaca 2550

 caaactgggt cttggataca cagttgtatt taatgtttta cgatctagcc 2600

 tttccagtac aggcactttc tgagaaacct ttgtcctcac ttgaggcatt 2650

 ttgttgtcgg gtttttgtgt ttgtttttgt gggtatttgc ctcattccac 2700

 ccctgagctt tcaggtagac agacgtgatt caaaactctg ttctaaggtg 2750

 tttattgtag tggagtaatg ggtttgcagt gataagtcat acttttccac 2800

 cgaaagggag ggcttgggaa tccctgagat tagctaaagt taagttgttg 2850

 gaagaattcc ttgattggaa attgtacctt tgtgttttgt tgctctgttt 2900

 cctgaaaata actcggggat gctcctggtt tgtccatcta ctgctttgat 2950

 tccttggatc ccacccattc tttcacttta agaaaaaaca aataattgtt 3000

 gcagaggtct ctgtattttg cagctgccct tttgtaagaa gcacttttcc 3050

 caaataaaac aattaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaa 3116

<210> 270
<211> 482
<212> PRT
<213> Homo sapien

<400> 270
 Met Ala Glu Ala Ala Thr Pro Gly Thr Thr Ala Thr Thr Ser Gly
   1               5                  10                  15

 Ala Gly Ala Ala Ala Ala Thr Ala Ala Ala Ala Ser Pro Thr Pro
                  20                  25                  30

 Ile Pro Thr Val Thr Ala Pro Ser Leu Gly Ala Gly Gly Gly Gly
                  35                  40                  45

 Gly Gly Ser Asp Gly Ser Gly Gly Gly Trp Thr Lys Gln Val Thr
                  50                  55                  60

 Cys Arg Tyr Phe Met His Gly Val Cys Lys Glu Gly Asp Asn Cys
                  65                  70                  75

 Arg Tyr Ser His Asp Leu Ser Asp Ser Pro Tyr Ser Val Val Cys
                  80                  85                  90

 Lys Tyr Phe Gln Arg Gly Tyr Cys Ile Tyr Gly Asp Arg Cys Arg
                  95                 100                 105

 Tyr Glu His Ser Lys Pro Leu Lys Gln Glu Glu Ala Thr Ala Thr
                 110                 115                 120

 Glu Leu Thr Thr Lys Ser Ser Leu Ala Ala Ser Ser Ser Leu Ser
                 125                 130                 135

 Ser Ile Val Gly Pro Leu Val Glu Met Asn Thr Gly Glu Ala Glu
                 140                 145                 150

 Ser Arg Asn Ser Asn Phe Ala Thr Val Gly Ala Gly Ser Glu Asp
                 155                 160                 165

 Trp Val Asn Ala Ile Glu Phe Val Pro Gly Gln Pro Tyr Cys Gly
                 170                 175                 180

 Arg Thr Ala Pro Ser Cys Thr Glu Ala Pro Leu Gln Gly Ser Val
                 185                 190                 195

 Thr Lys Glu Glu Ser Glu Lys Glu Gln Thr Ala Val Glu Thr Lys
                 200                 205                 210

 Lys Gln Leu Cys Pro Tyr Ala Ala Val Gly Glu Cys Arg Tyr Gly
                 215                 220                 225

 Glu Asn Cys Val Tyr Leu His Gly Asp Ser Cys Asp Met Cys Gly
                 230                 235                 240

 Leu Gln Leu Leu His Pro Met Asp Ala Ala Gln Arg Ser Gln His
                 245                 250                 255

 Ile Lys Ser Cys Ile Glu Ala His Glu Lys Asp Met Glu Leu Ser
                 260                 265                 270

 Phe Ala Val Gln Arg Ser Lys Asp Met Val Cys Gly Ile Cys Met
                 275                 280                 285

 Glu Val Val Tyr Glu Lys Ala Asn Pro Ser Glu Arg Arg Phe Gly
                 290                 295                 300

 Ile Leu Ser Asn Cys Asn His Thr Tyr Cys Leu Lys Cys Ile Arg
                 305                 310                 315

 Lys Trp Arg Ser Ala Lys Gln Phe Glu Ser Lys Ile Ile Lys Ser
                 320                 325                 330

 Cys Pro Glu Cys Arg Ile Thr Ser Asn Phe Val Ile Pro Ser Glu
                 335                 340                 345

 Tyr Trp Val Glu Glu Lys Glu Glu Lys Gln Lys Leu Ile Leu Lys
                 350                 355                 360

 Tyr Lys Glu Ala Met Ser Asn Lys Ala Cys Arg Tyr Phe Asp Glu
                 365                 370                 375

 Gly Arg Gly Ser Cys Pro Phe Gly Gly Asn Cys Phe Tyr Lys His
                 380                 385                 390

 Ala Tyr Pro Asp Gly Arg Arg Glu Glu Pro Gln Arg Gln Lys Val
                 395                 400                 405

 Gly Thr Ser Ser Arg Tyr Arg Ala Gln Arg Arg Asn His Phe Trp
                 410                 415                 420

 Glu Leu Ile Glu Glu Arg Glu Asn Ser Asn Pro Phe Asp Asn Asp
                 425                 430                 435

 Glu Glu Glu Val Val Thr Phe Glu Leu Gly Glu Met Leu Leu Met
                 440                 445                 450

 Leu Leu Ala Ala Gly Gly Asp Asp Glu Leu Thr Asp Ser Glu Asp
                 455                 460                 465

 Glu Trp Asp Leu Phe His Asp Glu Leu Glu Asp Phe Tyr Asp Leu
                 470                 475                 480

 Asp Leu


<210> 271
<211> 1249
<212> DNA
<213> Homo sapien

<400> 271
 ggcacgagcc agggtttcct cttcaagtag gtctaaaaca ttttttttct 50

 cattgacttc cttcctgttc taactgccag tactcagaag tcagagttga 100

 gagacagagg caccccggac agagacgtga agcactgaat aaatagatca 150

 gaatgactga aaaagcccca gagccacatg tggaggagga tgacgatgat 200

 gagctggaca gcaagctcaa ttataagcct ccaccacaga agtccctgaa 250

 agagctgcag gaaatggaca aagatgatga gagtctaatt aagtacaaga 300

 aaacgctgct gggagatggt cctgtggtga cagatccgaa agcccccaat 350

 gtcgttgtca cccggctcac cctggtttgt gagagtgccc cgggaccaat 400

 caccatggac cttactggag atctggaagc cctcaaaaag gaaaccattg 450

 tgttaaagga aggttctgaa tatagagtca aaattcactt caaagtgaac 500

 agggatattg tgtcaggcct gaaatacgtt cagcacacct acaggactgg 550

 ggtgaaagtg gataaagcaa catttatggt tggcagctat ggacctcggc 600

 ctgaggagta tgagttcctc actccagttg aggaggctcc caagggcatg 650

 ctggcccgag gcacgtacca caacaagtcc ttcttcaccg acgatgacaa 700

 gcaagaccac ctcagctggg agtggaacct gtcgattaag aaggagtgga 750

 cagaatgaat gcatccaccc cgttccccac ccttgccacc tggaagaatt 800

 ctctcaggcg tgttcagcac cctgtccctc ctccctgtcc acagctgggt 850

 ccctcttcaa cactgccaca tttccttatt gatcgatctt ttcccaccct 900

 gtcactcaac gtggtcccta gaacaagagg cttaaaaccg ggctttcacc 950

 caacctgctc cctctgatcc tccatcaggg ccagatcttc cacgtctcca 1000

 tctcagtaca caatcattta atatttccct gtcttacccc tattcaagca 1050

 actagaggcc agaaaatggg caaattatca ctaacaggtc tttgactcag 1100

 gttccagtag ttcattctaa tgcctagatt cttttgtggt tgttgctggc 1150

 ccaatgagtc cctagtcaca tcccctgcca gagggagttc ttcttttgtg 1200

 agagacactg taaacgacac aagagaacaa gaataaaaca ataactgtg 1249

<210> 272
<211> 201
<212> PRT
<213> Homo sapien

<400> 272
 Met Thr Glu Lys Ala Pro Glu Pro His Val Glu Glu Asp Asp Asp
   1               5                  10                  15

 Asp Glu Leu Asp Ser Lys Leu Asn Tyr Lys Pro Pro Pro Gln Lys
                  20                  25                  30

 Ser Leu Lys Glu Leu Gln Glu Met Asp Lys Asp Asp Glu Ser Leu
                  35                  40                  45

 Ile Lys Tyr Lys Lys Thr Leu Leu Gly Asp Gly Pro Val Val Thr
                  50                  55                  60

 Asp Pro Lys Ala Pro Asn Val Val Val Thr Arg Leu Thr Leu Val
                  65                  70                  75

 Cys Glu Ser Ala Pro Gly Pro Ile Thr Met Asp Leu Thr Gly Asp
                  80                  85                  90

 Leu Glu Ala Leu Lys Lys Glu Thr Ile Val Leu Lys Glu Gly Ser
                  95                 100                 105

 Glu Tyr Arg Val Lys Ile His Phe Lys Val Asn Arg Asp Ile Val
                 110                 115                 120

 Ser Gly Leu Lys Tyr Val Gln His Thr Tyr Arg Thr Gly Val Lys
                 125                 130                 135

 Val Asp Lys Ala Thr Phe Met Val Gly Ser Tyr Gly Pro Arg Pro
                 140                 145                 150

 Glu Glu Tyr Glu Phe Leu Thr Pro Val Glu Glu Ala Pro Lys Gly
                 155                 160                 165

 Met Leu Ala Arg Gly Thr Tyr His Asn Lys Ser Phe Phe Thr Asp
                 170                 175                 180

 Asp Asp Lys Gln Asp His Leu Ser Trp Glu Trp Asn Leu Ser Ile
                 185                 190                 195

 Lys Lys Glu Trp Thr Glu
                 200

<210> 273
<211> 5698
<212> DNA
<213> Homo sapien

<400> 273
 aggttcaagt ggagctctcc taaccgacgc gcgtctgtgg agaagcggct 50

 tggtcggggg tggtctcgtg gggtcctgcc tgtttagtcg ctttcagggt 100

 tcttgagccc cttcacgacc gtcaccatgg aagtgtcacc attgcagcct 150

 gtaaatgaaa atatgcaagt caacaaaata aagaaaaatg aagatgctaa 200

 gaaaagactg tctgttgaaa gaatctatca aaagaaaaca caattggaac 250

 atattttgct ccgcccagac acctacattg gttctgtgga attagtgacc 300

 cagcaaatgt gggtttacga tgaagatgtt ggcattaact atagggaagt 350

 cacttttgtt cctggtttgt acaaaatctt tgatgagatt ctagttaatg 400

 ctgcggacaa caaacaaagg gacccaaaaa tgtcttgtat tagagtcaca 450

 attgatccgg aaaacaattt aattagtata tggaataatg gaaaaggtat 500

 tcctgttgtt gaacacaaag ttgaaaagat gtatgtccca gctctcatat 550

 ttggacagct cctaacttct agtaactatg atgatgatga aaagaaagtg 600

 acaggtggtc gaaatggcta tggagccaaa ttgtgtaaca tattcagtac 650

 caaatttact gtggaaacag ccagtagaga atacaagaaa atgttcaaac 700

 agacatggat ggataatatg ggaagagctg gtgagatgga actcaagccc 750

 ttcaatggag aagattatac atgtatcacc tttcagcctg atttgtctaa 800

 gtttaaaatg caaagcctgg acaaagatat tgttgcacta atggtcagaa 850

 gagcatatga tattgctgga tccaccaaag atgtcaaagt ctttcttaat 900

 ggaaataaac tgccagtaaa aggatttcgt agttatgtgg acatgtattt 950

 gaaggacaag ttggatgaaa ctggtaactc cttgaaagta atacatgaac 1000

 aagtaaacca caggtgggaa gtgtgtttaa ctatgagtga aaaaggcttt 1050

 cagcaaatta gctttgtcaa cagcattgct acatccaagg gtggcagaca 1100

 tgttgattat gtagctgatc agattgtgac taaacttgtt gatgttgtga 1150

 agaagaagaa caagggtggt gttgcagtaa aagcacatca ggtgaaaaat 1200

 cacatgtgga tttttgtaaa tgccttaatt gaaaacccaa cctttgactc 1250

 tcagacaaaa gaaaacatga ctttacaacc caagagcttt ggatcaacat 1300

 gccaattgag tgaaaaattt atcaaagctg ccattggctg tggtattgta 1350

 gaaagcatac taaactgggt gaagtttaag gcccaagtcc agttaaacaa 1400

 gaagtgttca gctgtaaaac ataatagaat caagggaatt cccaaactcg 1450

 atgatgccaa tgatgcaggg ggccgaaact ccactgagtg tacgcttatc 1500

 ctgactgagg gagattcagc caaaactttg gctgtttcag gccttggtgt 1550

 ggttgggaga gacaaatatg gggttttccc tcttagagga aaaatactca 1600

 atgttcgaga agcttctcat aagcagatca tggaaaatgc tgagattaac 1650

 aatatcatca agattgtggg tcttcagtac aagaaaaact atgaagatga 1700

 agattcattg aagacgcttc gttatgggaa gataatgatt atgacagatc 1750

 aggaccaaga tggttcccac atcaaaggct tgctgattaa ttttatccat 1800

 cacaactggc cctctcttct gcgacatcgt tttctggagg aatttatcac 1850

 tcccattgta aaggtatcta aaaacaagca agaaatggca ttttacagcc 1900

 ttcctgaatt tgaagagtgg aagagttcta ctccaaatca taaaaaatgg 1950

 aaagtcaaat attacaaagg tttgggcacc agcacatcaa aggaagctaa 2000

 agaatacttt gcagatatga aaagacatcg tatccagttc aaatattctg 2050

 gtcctgaaga tgatgctgct atcagcctgg cctttagcaa aaaacagata 2100

 gatgatcgaa aggaatggtt aactaatttc atggaggata gaagacaacg 2150

 aaagttactt gggcttcctg aggattactt gtatggacaa actaccacat 2200

 atctgacata taatgacttc atcaacaagg aacttatctt gttctcaaat 2250

 tctgataacg agagatctat cccttctatg gtggatggtt tgaaaccagg 2300

 tcagagaaag gttttgttta cttgcttcaa acggaatgac aagcgagaag 2350

 taaaggttgc ccaattagct ggatcagtgg ctgaaatgtc ttcttatcat 2400

 catggtgaga tgtcactaat gatgaccatt atcaatttgg ctcagaattt 2450

 tgtgggtagc aataatctaa acctcttgca gcccattggt cagtttggta 2500

 ccaggctaca tggtggcaag gattctgcta gtccacgata catctttaca 2550

 atgctcagct ctttggctcg attgttattt ccaccaaaag atgatcacac 2600

 gttgaagttt ttatatgatg acaaccagcg tgttgagcct gaatggtaca 2650

 ttcctattat tcccatggtg ctgataaatg gtgctgaagg aatcggtact 2700

 gggtggtcct gcaaaatccc caactttgat gtgcgtgaaa ttgtaaataa 2750

 catcaggcgt ttgatggatg gagaagaacc tttgccaatg cttccaagtt 2800

 acaagaactt caagggtact attgaagaac tggctccaaa tcaatatgtg 2850

 attagtggtg aagtagctat tcttaattct acaaccattg aaatctcaga 2900

 gcttcccgtc agaacatgga cccagacata caaagaacaa gttctagaac 2950

 ccatgttgaa tggcaccgag aagacacctc ctctcataac agactatagg 3000

 gaataccata cagataccac tgtgaaattt gttgtgaaga tgactgaaga 3050

 aaaactggca gaggcagaga gagttggact acacaaagtc ttcaaactcc 3100

 aaactagtct cacatgcaac tctatggtgc tttttgacca cgtaggctgt 3150

 ttaaagaaat atgacacggt gttggatatt ctaagagact tttttgaact 3200

 cagacttaaa tattatggat taagaaaaga atggctccta ggaatgcttg 3250

 gtgctgaatc tgctaaactg aataatcagg ctcgctttat cttagagaaa 3300

 atagatggca aaataatcat tgaaaataag cctaagaaag aattaattaa 3350

 agttctgatt cagaggggat atgattcgga tcctgtgaag gcctggaaag 3400

 aagcccagca aaaggttcca gatgaagaag aaaatgaaga gagtgacaac 3450

 gaaaaggaaa ctgaaaagag tgactccgta acagattctg gaccaacctt 3500

 caactatctt cttgatatgc ccctttggta tttaaccaag gaaaagaaag 3550

 atgaactctg caggctaaga aatgaaaaag aacaagagct ggacacatta 3600

 aaaagaaaga gtccatcaga tttgtggaaa gaagacttgg ctacatttat 3650

 tgaagaattg gaggctgttg aagccaagga aaaacaagat gaacaagtcg 3700

 gacttcctgg gaaagggggg aaggccaagg ggaaaaaaac acaaatggct 3750

 gaagttttgc cttctccgcg tggtcaaaga gtcattccac gaataaccat 3800

 agaaatgaaa gcagaggcag aaaagaaaaa taaaaagaaa attaagaatg 3850

 aaaatactga aggaagccct caagaagatg gtgtggaact agaaggccta 3900

 aaacaaagat tagaaaagaa acagaaaaga gaaccaggta caaagacaaa 3950

 gaaacaaact acattggcat ttaagccaat caaaaaagga aagaagagaa 4000

 atccctggtc tgattcagaa tcagatagga gcagtgacga aagtaatttt 4050

 gatgtccctc cacgagaaac agagccacgg agagcagcaa caaaaacaaa 4100

 attcacaatg gatttggatt cagatgaaga tttctcagat tttgatgaaa 4150

 aaactgatga tgaagatttt gtcccatcag atgctagtcc acctaagacc 4200

 aaaacttccc caaaacttag taacaaagaa ctgaaaccac agaaaagtgt 4250

 cgtgtcagac cttgaagctg atgatgttaa gggcagtgta ccactgtctt 4300

 caagccctcc tgctacacat ttcccagatg aaactgaaat tacaaaccca 4350

 gttcctaaaa agaatgtgac agtgaagaag acagcagcaa aaagtcagtc 4400

 ttccacctcc actaccggtg ccaaaaaaag ggctgcccca aaaggaacta 4450

 aaagggatcc agctttgaat tctggtgtct ctcaaaagcc tgatcctgcc 4500

 aaaaccaaga atcgccgcaa aaggaagcca tccacttctg atgattctga 4550

 ctctaatttt gagaaaattg tttcgaaagc agtcacaagc aagaaatcca 4600

 agggggagag tgatgacttc catatggact ttgactcagc tgtggctcct 4650

 cgggcaaaat ctgtacgggc aaagaaacct ataaagtacc tggaagagtc 4700

 agatgaagat gatctgtttt aaaatgtgag gcgattattt taagtaatta 4750

 tcttaccaag cccaagactg gttttaaagt tacctgaagc tcttaacttc 4800

 ctcccctctg aatttagttt ggggaaggtg tttttagtac aagacatcaa 4850

 agtgaagtaa agcccaagtg ttctttagct ttttataata ctgtctaaat 4900

 agtgaccatc tcatgggcat tgttttcttc tctgctttgt ctgtgttttg 4950

 agtctgcttt cttttgtctt taaaacctga tttttaagtt cttctgaact 5000

 gtagaaatag ctatctgatc acttcagcgt aaagcagtgt gtttattaac 5050

 catccactaa gctaaaacta gagcagtttg atttaaaagt gtcactcttc 5100

 ctccttttct actttcagta gatatgagat agagcataat tatctgtttt 5150

 atcttagttt tatacataat ttaccatcag atagaacttt atggttctag 5200

 tacagatact ctactacact cagcctctta tgtgccaagt ttttctttaa 5250

 gcaatgagaa attgctcatg ttcttcatct tctcaaatca tcagaggcca 5300

 aagaaaaaca ctttggctgt gtctataact tgacacagtc aatagaatga 5350

 agaaaattag agtagttatg tgattatttc agctcttgac ctgtcccctc 5400

 tggctgcctc tgagtctgaa tctcccaaag agagaaacca atttctaaga 5450

 ggactggatt gcagaagact cggggacaac atttgatcca agatcttaaa 5500

 tgttatattg ataaccatgc tcagcaatga gctattagat tcattttggg 5550

 aaatctccat aatttcaatt tgtaaacttt gttaagacct gtctacattg 5600

 ttatatgtgt gtgacttgag taatgttatc aacgtttttg taaatattta 5650

 ctatgttttt ctattagcta aattccaaca attttgtact ttaataaa 5698

<210> 274
<211> 1531
<212> PRT
<213> Homo sapien

<400> 274
 Met Glu Val Ser Pro Leu Gln Pro Val Asn Glu Asn Met Gln Val
   1               5                  10                  15

 Asn Lys Ile Lys Lys Asn Glu Asp Ala Lys Lys Arg Leu Ser Val
                  20                  25                  30

 Glu Arg Ile Tyr Gln Lys Lys Thr Gln Leu Glu His Ile Leu Leu
                  35                  40                  45

 Arg Pro Asp Thr Tyr Ile Gly Ser Val Glu Leu Val Thr Gln Gln
                  50                  55                  60

 Met Trp Val Tyr Asp Glu Asp Val Gly Ile Asn Tyr Arg Glu Val
                  65                  70                  75

 Thr Phe Val Pro Gly Leu Tyr Lys Ile Phe Asp Glu Ile Leu Val
                  80                  85                  90

 Asn Ala Ala Asp Asn Lys Gln Arg Asp Pro Lys Met Ser Cys Ile
                  95                 100                 105

 Arg Val Thr Ile Asp Pro Glu Asn Asn Leu Ile Ser Ile Trp Asn
                 110                 115                 120

 Asn Gly Lys Gly Ile Pro Val Val Glu His Lys Val Glu Lys Met
                 125                 130                 135

 Tyr Val Pro Ala Leu Ile Phe Gly Gln Leu Leu Thr Ser Ser Asn
                 140                 145                 150

 Tyr Asp Asp Asp Glu Lys Lys Val Thr Gly Gly Arg Asn Gly Tyr
                 155                 160                 165

 Gly Ala Lys Leu Cys Asn Ile Phe Ser Thr Lys Phe Thr Val Glu
                 170                 175                 180

 Thr Ala Ser Arg Glu Tyr Lys Lys Met Phe Lys Gln Thr Trp Met
                 185                 190                 195

 Asp Asn Met Gly Arg Ala Gly Glu Met Glu Leu Lys Pro Phe Asn
                 200                 205                 210

 Gly Glu Asp Tyr Thr Cys Ile Thr Phe Gln Pro Asp Leu Ser Lys
                 215                 220                 225

 Phe Lys Met Gln Ser Leu Asp Lys Asp Ile Val Ala Leu Met Val
                 230                 235                 240

 Arg Arg Ala Tyr Asp Ile Ala Gly Ser Thr Lys Asp Val Lys Val
                 245                 250                 255

 Phe Leu Asn Gly Asn Lys Leu Pro Val Lys Gly Phe Arg Ser Tyr
                 260                 265                 270

 Val Asp Met Tyr Leu Lys Asp Lys Leu Asp Glu Thr Gly Asn Ser
                 275                 280                 285

 Leu Lys Val Ile His Glu Gln Val Asn His Arg Trp Glu Val Cys
                 290                 295                 300

 Leu Thr Met Ser Glu Lys Gly Phe Gln Gln Ile Ser Phe Val Asn
                 305                 310                 315

 Ser Ile Ala Thr Ser Lys Gly Gly Arg His Val Asp Tyr Val Ala
                 320                 325                 330

 Asp Gln Ile Val Thr Lys Leu Val Asp Val Val Lys Lys Lys Asn
                 335                 340                 345

 Lys Gly Gly Val Ala Val Lys Ala His Gln Val Lys Asn His Met
                 350                 355                 360

 Trp Ile Phe Val Asn Ala Leu Ile Glu Asn Pro Thr Phe Asp Ser
                 365                 370                 375

 Gln Thr Lys Glu Asn Met Thr Leu Gln Pro Lys Ser Phe Gly Ser
                 380                 385                 390

 Thr Cys Gln Leu Ser Glu Lys Phe Ile Lys Ala Ala Ile Gly Cys
                 395                 400                 405

 Gly Ile Val Glu Ser Ile Leu Asn Trp Val Lys Phe Lys Ala Gln
                 410                 415                 420

 Val Gln Leu Asn Lys Lys Cys Ser Ala Val Lys His Asn Arg Ile
                 425                 430                 435

 Lys Gly Ile Pro Lys Leu Asp Asp Ala Asn Asp Ala Gly Gly Arg
                 440                 445                 450

 Asn Ser Thr Glu Cys Thr Leu Ile Leu Thr Glu Gly Asp Ser Ala
                 455                 460                 465

 Lys Thr Leu Ala Val Ser Gly Leu Gly Val Val Gly Arg Asp Lys
                 470                 475                 480

 Tyr Gly Val Phe Pro Leu Arg Gly Lys Ile Leu Asn Val Arg Glu
                 485                 490                 495

 Ala Ser His Lys Gln Ile Met Glu Asn Ala Glu Ile Asn Asn Ile
                 500                 505                 510

 Ile Lys Ile Val Gly Leu Gln Tyr Lys Lys Asn Tyr Glu Asp Glu
                 515                 520                 525

 Asp Ser Leu Lys Thr Leu Arg Tyr Gly Lys Ile Met Ile Met Thr
                 530                 535                 540

 Asp Gln Asp Gln Asp Gly Ser His Ile Lys Gly Leu Leu Ile Asn
                 545                 550                 555

 Phe Ile His His Asn Trp Pro Ser Leu Leu Arg His Arg Phe Leu
                 560                 565                 570

 Glu Glu Phe Ile Thr Pro Ile Val Lys Val Ser Lys Asn Lys Gln
                 575                 580                 585

 Glu Met Ala Phe Tyr Ser Leu Pro Glu Phe Glu Glu Trp Lys Ser
                 590                 595                 600

 Ser Thr Pro Asn His Lys Lys Trp Lys Val Lys Tyr Tyr Lys Gly
                 605                 610                 615

 Leu Gly Thr Ser Thr Ser Lys Glu Ala Lys Glu Tyr Phe Ala Asp
                 620                 625                 630

 Met Lys Arg His Arg Ile Gln Phe Lys Tyr Ser Gly Pro Glu Asp
                 635                 640                 645

 Asp Ala Ala Ile Ser Leu Ala Phe Ser Lys Lys Gln Ile Asp Asp
                 650                 655                 660

 Arg Lys Glu Trp Leu Thr Asn Phe Met Glu Asp Arg Arg Gln Arg
                 665                 670                 675

 Lys Leu Leu Gly Leu Pro Glu Asp Tyr Leu Tyr Gly Gln Thr Thr
                 680                 685                 690

 Thr Tyr Leu Thr Tyr Asn Asp Phe Ile Asn Lys Glu Leu Ile Leu
                 695                 700                 705

 Phe Ser Asn Ser Asp Asn Glu Arg Ser Ile Pro Ser Met Val Asp
                 710                 715                 720

 Gly Leu Lys Pro Gly Gln Arg Lys Val Leu Phe Thr Cys Phe Lys
                 725                 730                 735

 Arg Asn Asp Lys Arg Glu Val Lys Val Ala Gln Leu Ala Gly Ser
                 740                 745                 750

 Val Ala Glu Met Ser Ser Tyr His His Gly Glu Met Ser Leu Met
                 755                 760                 765

 Met Thr Ile Ile Asn Leu Ala Gln Asn Phe Val Gly Ser Asn Asn
                 770                 775                 780

 Leu Asn Leu Leu Gln Pro Ile Gly Gln Phe Gly Thr Arg Leu His
                 785                 790                 795

 Gly Gly Lys Asp Ser Ala Ser Pro Arg Tyr Ile Phe Thr Met Leu
                 800                 805                 810

 Ser Ser Leu Ala Arg Leu Leu Phe Pro Pro Lys Asp Asp His Thr
                 815                 820                 825

 Leu Lys Phe Leu Tyr Asp Asp Asn Gln Arg Val Glu Pro Glu Trp
                 830                 835                 840

 Tyr Ile Pro Ile Ile Pro Met Val Leu Ile Asn Gly Ala Glu Gly
                 845                 850                 855

 Ile Gly Thr Gly Trp Ser Cys Lys Ile Pro Asn Phe Asp Val Arg
                 860                 865                 870

 Glu Ile Val Asn Asn Ile Arg Arg Leu Met Asp Gly Glu Glu Pro
                 875                 880                 885

 Leu Pro Met Leu Pro Ser Tyr Lys Asn Phe Lys Gly Thr Ile Glu
                 890                 895                 900

 Glu Leu Ala Pro Asn Gln Tyr Val Ile Ser Gly Glu Val Ala Ile
                 905                 910                 915

 Leu Asn Ser Thr Thr Ile Glu Ile Ser Glu Leu Pro Val Arg Thr
                 920                 925                 930

 Trp Thr Gln Thr Tyr Lys Glu Gln Val Leu Glu Pro Met Leu Asn
                 935                 940                 945

 Gly Thr Glu Lys Thr Pro Pro Leu Ile Thr Asp Tyr Arg Glu Tyr
                 950                 955                 960

 His Thr Asp Thr Thr Val Lys Phe Val Val Lys Met Thr Glu Glu
                 965                 970                 975

 Lys Leu Ala Glu Ala Glu Arg Val Gly Leu His Lys Val Phe Lys
                 980                 985                 990

 Leu Gln Thr Ser Leu Thr Cys Asn Ser Met Val Leu Phe Asp His
                 995                1000                1005

 Val Gly Cys Leu Lys Lys Tyr Asp Thr Val Leu Asp Ile Leu Arg
                1010                1015                1020

 Asp Phe Phe Glu Leu Arg Leu Lys Tyr Tyr Gly Leu Arg Lys Glu
                1025                1030                1035

 Trp Leu Leu Gly Met Leu Gly Ala Glu Ser Ala Lys Leu Asn Asn
                1040                1045                1050

 Gln Ala Arg Phe Ile Leu Glu Lys Ile Asp Gly Lys Ile Ile Ile
                1055                1060                1065

 Glu Asn Lys Pro Lys Lys Glu Leu Ile Lys Val Leu Ile Gln Arg
                1070                1075                1080

 Gly Tyr Asp Ser Asp Pro Val Lys Ala Trp Lys Glu Ala Gln Gln
                1085                1090                1095

 Lys Val Pro Asp Glu Glu Glu Asn Glu Glu Ser Asp Asn Glu Lys
                1100                1105                1110

 Glu Thr Glu Lys Ser Asp Ser Val Thr Asp Ser Gly Pro Thr Phe
                1115                1120                1125

 Asn Tyr Leu Leu Asp Met Pro Leu Trp Tyr Leu Thr Lys Glu Lys
                1130                1135                1140

 Lys Asp Glu Leu Cys Arg Leu Arg Asn Glu Lys Glu Gln Glu Leu
                1145                1150                1155

 Asp Thr Leu Lys Arg Lys Ser Pro Ser Asp Leu Trp Lys Glu Asp
                1160                1165                1170

 Leu Ala Thr Phe Ile Glu Glu Leu Glu Ala Val Glu Ala Lys Glu
                1175                1180                1185

 Lys Gln Asp Glu Gln Val Gly Leu Pro Gly Lys Gly Gly Lys Ala
                1190                1195                1200

 Lys Gly Lys Lys Thr Gln Met Ala Glu Val Leu Pro Ser Pro Arg
                1205                1210                1215

 Gly Gln Arg Val Ile Pro Arg Ile Thr Ile Glu Met Lys Ala Glu
                1220                1225                1230

 Ala Glu Lys Lys Asn Lys Lys Lys Ile Lys Asn Glu Asn Thr Glu
                1235                1240                1245

 Gly Ser Pro Gln Glu Asp Gly Val Glu Leu Glu Gly Leu Lys Gln
                1250                1255                1260

 Arg Leu Glu Lys Lys Gln Lys Arg Glu Pro Gly Thr Lys Thr Lys
                1265                1270                1275

 Lys Gln Thr Thr Leu Ala Phe Lys Pro Ile Lys Lys Gly Lys Lys
                1280                1285                1290

 Arg Asn Pro Trp Ser Asp Ser Glu Ser Asp Arg Ser Ser Asp Glu
                1295                1300                1305

 Ser Asn Phe Asp Val Pro Pro Arg Glu Thr Glu Pro Arg Arg Ala
                1310                1315                1320

 Ala Thr Lys Thr Lys Phe Thr Met Asp Leu Asp Ser Asp Glu Asp
                1325                1330                1335

 Phe Ser Asp Phe Asp Glu Lys Thr Asp Asp Glu Asp Phe Val Pro
                1340                1345                1350

 Ser Asp Ala Ser Pro Pro Lys Thr Lys Thr Ser Pro Lys Leu Ser
                1355                1360                1365

 Asn Lys Glu Leu Lys Pro Gln Lys Ser Val Val Ser Asp Leu Glu
                1370                1375                1380

 Ala Asp Asp Val Lys Gly Ser Val Pro Leu Ser Ser Ser Pro Pro
                1385                1390                1395

 Ala Thr His Phe Pro Asp Glu Thr Glu Ile Thr Asn Pro Val Pro
                1400                1405                1410

 Lys Lys Asn Val Thr Val Lys Lys Thr Ala Ala Lys Ser Gln Ser
                1415                1420                1425

 Ser Thr Ser Thr Thr Gly Ala Lys Lys Arg Ala Ala Pro Lys Gly
                1430                1435                1440

 Thr Lys Arg Asp Pro Ala Leu Asn Ser Gly Val Ser Gln Lys Pro
                1445                1450                1455

 Asp Pro Ala Lys Thr Lys Asn Arg Arg Lys Arg Lys Pro Ser Thr
                1460                1465                1470

 Ser Asp Asp Ser Asp Ser Asn Phe Glu Lys Ile Val Ser Lys Ala
                1475                1480                1485

 Val Thr Ser Lys Lys Ser Lys Gly Glu Ser Asp Asp Phe His Met
                1490                1495                1500

 Asp Phe Asp Ser Ala Val Ala Pro Arg Ala Lys Ser Val Arg Ala
                1505                1510                1515

 Lys Lys Pro Ile Lys Tyr Leu Glu Glu Ser Asp Glu Asp Asp Leu
                1520                1525                1530

 Phe


<210> 275
<211> 5698
<212> DNA
<213> Homo sapien

<400> 275
 aggttcaagt ggagctctcc taaccgacgc gcgtctgtgg agaagcggct 50

 tggtcggggg tggtctcgtg gggtcctgcc tgtttagtcg ctttcagggt 100

 tcttgagccc cttcacgacc gtcaccatgg aagtgtcacc attgcagcct 150

 gtaaatgaaa atatgcaagt caacaaaata aagaaaaatg aagatgctaa 200

 gaaaagactg tctgttgaaa gaatctatca aaagaaaaca caattggaac 250

 atattttgct ccgcccagac acctacattg gttctgtgga attagtgacc 300

 cagcaaatgt gggtttacga tgaagatgtt ggcattaact atagggaagt 350

 cacttttgtt cctggtttgt acaaaatctt tgatgagatt ctagttaatg 400

 ctgcggacaa caaacaaagg gacccaaaaa tgtcttgtat tagagtcaca 450

 attgatccgg aaaacaattt aattagtata tggaataatg gaaaaggtat 500

 tcctgttgtt gaacacaaag ttgaaaagat gtatgtccca gctctcatat 550

 ttggacagct cctaacttct agtaactatg atgatgatga aaagaaagtg 600

 acaggtggtc gaaatggcta tggagccaaa ttgtgtaaca tattcagtac 650

 caaatttact gtggaaacag ccagtagaga atacaagaaa atgttcaaac 700

 agacatggat ggataatatg ggaagagctg gtgagatgga actcaagccc 750

 ttcaatggag aagattatac atgtatcacc tttcagcctg atttgtctaa 800

 gtttaaaatg caaagcctgg acaaagatat tgttgcacta atggtcagaa 850

 gagcatatga tattgctgga tccaccaaag atgtcaaagt ctttcttaat 900

 ggaaataaac tgccagtaaa aggatttcgt agttatgtgg acatgtattt 950

 gaaggacaag ttggatgaaa ctggtaactc cttgaaagta atacatgaac 1000

 aagtaaacca caggtgggaa gtgtgtttaa ctatgagtga aaaaggcttt 1050

 cagcaaatta gctttgtcaa cagcattgct acatccaagg gtggcagaca 1100

 tgttgattat gtagctgatc agattgtgac taaacttgtt gatgttgtga 1150

 agaagaagaa caagggtggt gttgcagtaa aagcacatca ggtgaaaaat 1200

 cacatgtgga tttttgtaaa tgccttaatt gaaaacccaa cctttgactc 1250

 tcagacaaaa gaaaacatga ctttacaacc caagagcttt ggatcaacat 1300

 gccaattgag tgaaaaattt atcaaagctg ccattggctg tggtattgta 1350

 gaaagcatac taaactgggt gaagtttaag gcccaagtcc agttaaacaa 1400

 gaagtgttca gctgtaaaac ataatagaat caagggaatt cccaaactcg 1450

 atgatgccaa tgatgcaggg ggccgaaact ccactgagtg tacgcttatc 1500

 ctgactgagg gagattcagc caaaactttg gctgtttcag gccttggtgt 1550

 ggttgggaga gacaaatatg gggttttccc tcttagagga aaaatactca 1600

 atgttcgaga agcttctcat aagcagatca tggaaaatgc tgagattaac 1650

 aatatcatca agattgtggg tcttcagtac aagaaaaact atgaagatga 1700

 agattcattg aagacgcttc gttatgggaa gataatgatt atgacagatc 1750

 aggaccaaga tggttcccac atcaaaggct tgctgattaa ttttatccat 1800

 cacaactggc cctctcttct gcgacatcgt tttctggagg aatttatcac 1850

 tcccattgta aaggtatcta aaaacaagca agaaatggca ttttacagcc 1900

 ttcctgaatt tgaagagtgg aagagttcta ctccaaatca taaaaaatgg 1950

 aaagtcaaat attacaaagg tttgggcacc agcacatcaa aggaagctaa 2000

 agaatacttt gcagatatga aaagacatcg tatccagttc aaatattctg 2050

 gtcctgaaga tgatgctgct atcagcctgg cctttagcaa aaaacagata 2100

 gatgatcgaa aggaatggtt aactaatttc atggaggata gaagacaacg 2150

 aaagttactt gggcttcctg aggattactt gtatggacaa actaccacat 2200

 atctgacata taatgacttc atcaacaagg aacttatctt gttctcaaat 2250

 tctgataacg agagatctat cccttctatg gtggatggtt tgaaaccagg 2300

 tcagagaaag gttttgttta cttgcttcaa acggaatgac aagcgagaag 2350

 taaaggttgc ccaattagct ggatcagtgg ctgaaatgtc ttcttatcat 2400

 catggtgaga tgtcactaat gatgaccatt atcaatttgg ctcagaattt 2450

 tgtgggtagc aataatctaa acctcttgca gcccattggt cagtttggta 2500

 ccaggctaca tggtggcaag gattctgcta gtccacgata catctttaca 2550

 atgctcagct ctttggctcg attgttattt ccaccaaaag atgatcacac 2600

 gttgaagttt ttatatgatg acaaccagcg tgttgagcct gaatggtaca 2650

 ttcctattat tcccatggtg ctgataaatg gtgctgaagg aatcggtact 2700

 gggtggtcct gcaaaatccc caactttgat gtgcgtgaaa ttgtaaataa 2750

 catcaggcgt ttgatggatg gagaagaacc tttgccaatg cttccaagtt 2800

 acaagaactt caagggtact attgaagaac tggctccaaa tcaatatgtg 2850

 attagtggtg aagtagctat tcttaattct acaaccattg aaatctcaga 2900

 gcttcccgtc agaacatgga cccagacata caaagaacaa gttctagaac 2950

 ccatgttgaa tggcaccgag aagacacctc ctctcataac agactatagg 3000

 gaataccata cagataccac tgtgaaattt gttgtgaaga tgactgaaga 3050

 aaaactggca gaggcagaga gagttggact acacaaagtc ttcaaactcc 3100

 aaactagtct cacatgcaac tctatggtgc tttttgacca cgtaggctgt 3150

 ttaaagaaat atgacacggt gttggatatt ctaagagact tttttgaact 3200

 cagacttaaa tattatggat taagaaaaga atggctccta ggaatgcttg 3250

 gtgctgaatc tgctaaactg aataatcagg ctcgctttat cttagagaaa 3300

 atagatggca aaataatcat tgaaaataag cctaagaaag aattaattaa 3350

 agttctgatt cagaggggat atgattcgga tcctgtgaag gcctggaaag 3400

 aagcccagca aaaggttcca gatgaagaag aaaatgaaga gagtgacaac 3450

 gaaaaggaaa ctgaaaagag tgactccgta acagattctg gaccaacctt 3500

 caactatctt cttgatatgc ccctttggta tttaaccaag gaaaagaaag 3550

 atgaactctg caggctaaga aatgaaaaag aacaagagct ggacacatta 3600

 aaaagaaaga gtccatcaga tttgtggaaa gaagacttgg ctacatttat 3650

 tgaagaattg gaggctgttg aagccaagga aaaacaagat gaacaagtcg 3700

 gacttcctgg gaaagggggg aaggccaagg ggaaaaaaac acaaatggct 3750

 gaagttttgc cttctccgcg tggtcaaaga gtcattccac gaataaccat 3800

 agaaatgaaa gcagaggcag aaaagaaaaa taaaaagaaa attaagaatg 3850

 aaaatactga aggaagccct caagaagatg gtgtggaact agaaggccta 3900

 aaacaaagat tagaaaagaa acagaaaaga gaaccaggta caaagacaaa 3950

 gaaacaaact acattggcat ttaagccaat caaaaaagga aagaagagaa 4000

 atccctggtc tgattcagaa tcagatagga gcagtgacga aagtaatttt 4050

 gatgtccctc cacgagaaac agagccacgg agagcagcaa caaaaacaaa 4100

 attcacaatg gatttggatt cagatgaaga tttctcagat tttgatgaaa 4150

 aaactgatga tgaagatttt gtcccatcag atgctagtcc acctaagacc 4200

 aaaacttccc caaaacttag taacaaagaa ctgaaaccac agaaaagtgt 4250

 cgtgtcagac cttgaagctg atgatgttaa gggcagtgta ccactgtctt 4300

 caagccctcc tgctacacat ttcccagatg aaactgaaat tacaaaccca 4350

 gttcctaaaa agaatgtgac agtgaagaag acagcagcaa aaagtcagtc 4400

 ttccacctcc actaccggtg ccaaaaaaag ggctgcccca aaaggaacta 4450

 aaagggatcc agctttgaat tctggtgtct ctcaaaagcc tgatcctgcc 4500

 aaaaccaaga atcgccgcaa aaggaagcca tccacttctg atgattctga 4550

 ctctaatttt gagaaaattg tttcgaaagc agtcacaagc aagaaatcca 4600

 agggggagag tgatgacttc catatggact ttgactcagc tgtggctcct 4650

 cgggcaaaat ctgtacgggc aaagaaacct ataaagtacc tggaagagtc 4700

 agatgaagat gatctgtttt aaaatgtgag gcgattattt taagtaatta 4750

 tcttaccaag cccaagactg gttttaaagt tacctgaagc tcttaacttc 4800

 ctcccctctg aatttagttt ggggaaggtg tttttagtac aagacatcaa 4850

 agtgaagtaa agcccaagtg ttctttagct ttttataata ctgtctaaat 4900

 agtgaccatc tcatgggcat tgttttcttc tctgctttgt ctgtgttttg 4950

 agtctgcttt cttttgtctt taaaacctga tttttaagtt cttctgaact 5000

 gtagaaatag ctatctgatc acttcagcgt aaagcagtgt gtttattaac 5050

 catccactaa gctaaaacta gagcagtttg atttaaaagt gtcactcttc 5100

 ctccttttct actttcagta gatatgagat agagcataat tatctgtttt 5150

 atcttagttt tatacataat ttaccatcag atagaacttt atggttctag 5200

 tacagatact ctactacact cagcctctta tgtgccaagt ttttctttaa 5250

 gcaatgagaa attgctcatg ttcttcatct tctcaaatca tcagaggcca 5300

 aagaaaaaca ctttggctgt gtctataact tgacacagtc aatagaatga 5350

 agaaaattag agtagttatg tgattatttc agctcttgac ctgtcccctc 5400

 tggctgcctc tgagtctgaa tctcccaaag agagaaacca atttctaaga 5450

 ggactggatt gcagaagact cggggacaac atttgatcca agatcttaaa 5500

 tgttatattg ataaccatgc tcagcaatga gctattagat tcattttggg 5550

 aaatctccat aatttcaatt tgtaaacttt gttaagacct gtctacattg 5600

 ttatatgtgt gtgacttgag taatgttatc aacgtttttg taaatattta 5650

 ctatgttttt ctattagcta aattccaaca attttgtact ttaataaa 5698

<210> 276
<211> 1531
<212> PRT
<213> Homo sapien

<400> 276
 Met Glu Val Ser Pro Leu Gln Pro Val Asn Glu Asn Met Gln Val
   1               5                  10                  15

 Asn Lys Ile Lys Lys Asn Glu Asp Ala Lys Lys Arg Leu Ser Val
                  20                  25                  30

 Glu Arg Ile Tyr Gln Lys Lys Thr Gln Leu Glu His Ile Leu Leu
                  35                  40                  45

 Arg Pro Asp Thr Tyr Ile Gly Ser Val Glu Leu Val Thr Gln Gln
                  50                  55                  60

 Met Trp Val Tyr Asp Glu Asp Val Gly Ile Asn Tyr Arg Glu Val
                  65                  70                  75

 Thr Phe Val Pro Gly Leu Tyr Lys Ile Phe Asp Glu Ile Leu Val
                  80                  85                  90

 Asn Ala Ala Asp Asn Lys Gln Arg Asp Pro Lys Met Ser Cys Ile
                  95                 100                 105

 Arg Val Thr Ile Asp Pro Glu Asn Asn Leu Ile Ser Ile Trp Asn
                 110                 115                 120

 Asn Gly Lys Gly Ile Pro Val Val Glu His Lys Val Glu Lys Met
                 125                 130                 135

 Tyr Val Pro Ala Leu Ile Phe Gly Gln Leu Leu Thr Ser Ser Asn
                 140                 145                 150

 Tyr Asp Asp Asp Glu Lys Lys Val Thr Gly Gly Arg Asn Gly Tyr
                 155                 160                 165

 Gly Ala Lys Leu Cys Asn Ile Phe Ser Thr Lys Phe Thr Val Glu
                 170                 175                 180

 Thr Ala Ser Arg Glu Tyr Lys Lys Met Phe Lys Gln Thr Trp Met
                 185                 190                 195

 Asp Asn Met Gly Arg Ala Gly Glu Met Glu Leu Lys Pro Phe Asn
                 200                 205                 210

 Gly Glu Asp Tyr Thr Cys Ile Thr Phe Gln Pro Asp Leu Ser Lys
                 215                 220                 225

 Phe Lys Met Gln Ser Leu Asp Lys Asp Ile Val Ala Leu Met Val
                 230                 235                 240

 Arg Arg Ala Tyr Asp Ile Ala Gly Ser Thr Lys Asp Val Lys Val
                 245                 250                 255

 Phe Leu Asn Gly Asn Lys Leu Pro Val Lys Gly Phe Arg Ser Tyr
                 260                 265                 270

 Val Asp Met Tyr Leu Lys Asp Lys Leu Asp Glu Thr Gly Asn Ser
                 275                 280                 285

 Leu Lys Val Ile His Glu Gln Val Asn His Arg Trp Glu Val Cys
                 290                 295                 300

 Leu Thr Met Ser Glu Lys Gly Phe Gln Gln Ile Ser Phe Val Asn
                 305                 310                 315

 Ser Ile Ala Thr Ser Lys Gly Gly Arg His Val Asp Tyr Val Ala
                 320                 325                 330

 Asp Gln Ile Val Thr Lys Leu Val Asp Val Val Lys Lys Lys Asn
                 335                 340                 345

 Lys Gly Gly Val Ala Val Lys Ala His Gln Val Lys Asn His Met
                 350                 355                 360

 Trp Ile Phe Val Asn Ala Leu Ile Glu Asn Pro Thr Phe Asp Ser
                 365                 370                 375

 Gln Thr Lys Glu Asn Met Thr Leu Gln Pro Lys Ser Phe Gly Ser
                 380                 385                 390

 Thr Cys Gln Leu Ser Glu Lys Phe Ile Lys Ala Ala Ile Gly Cys
                 395                 400                 405

 Gly Ile Val Glu Ser Ile Leu Asn Trp Val Lys Phe Lys Ala Gln
                 410                 415                 420

 Val Gln Leu Asn Lys Lys Cys Ser Ala Val Lys His Asn Arg Ile
                 425                 430                 435

 Lys Gly Ile Pro Lys Leu Asp Asp Ala Asn Asp Ala Gly Gly Arg
                 440                 445                 450

 Asn Ser Thr Glu Cys Thr Leu Ile Leu Thr Glu Gly Asp Ser Ala
                 455                 460                 465

 Lys Thr Leu Ala Val Ser Gly Leu Gly Val Val Gly Arg Asp Lys
                 470                 475                 480

 Tyr Gly Val Phe Pro Leu Arg Gly Lys Ile Leu Asn Val Arg Glu
                 485                 490                 495

 Ala Ser His Lys Gln Ile Met Glu Asn Ala Glu Ile Asn Asn Ile
                 500                 505                 510

 Ile Lys Ile Val Gly Leu Gln Tyr Lys Lys Asn Tyr Glu Asp Glu
                 515                 520                 525

 Asp Ser Leu Lys Thr Leu Arg Tyr Gly Lys Ile Met Ile Met Thr
                 530                 535                 540

 Asp Gln Asp Gln Asp Gly Ser His Ile Lys Gly Leu Leu Ile Asn
                 545                 550                 555

 Phe Ile His His Asn Trp Pro Ser Leu Leu Arg His Arg Phe Leu
                 560                 565                 570

 Glu Glu Phe Ile Thr Pro Ile Val Lys Val Ser Lys Asn Lys Gln
                 575                 580                 585

 Glu Met Ala Phe Tyr Ser Leu Pro Glu Phe Glu Glu Trp Lys Ser
                 590                 595                 600

 Ser Thr Pro Asn His Lys Lys Trp Lys Val Lys Tyr Tyr Lys Gly
                 605                 610                 615

 Leu Gly Thr Ser Thr Ser Lys Glu Ala Lys Glu Tyr Phe Ala Asp
                 620                 625                 630

 Met Lys Arg His Arg Ile Gln Phe Lys Tyr Ser Gly Pro Glu Asp
                 635                 640                 645

 Asp Ala Ala Ile Ser Leu Ala Phe Ser Lys Lys Gln Ile Asp Asp
                 650                 655                 660

 Arg Lys Glu Trp Leu Thr Asn Phe Met Glu Asp Arg Arg Gln Arg
                 665                 670                 675

 Lys Leu Leu Gly Leu Pro Glu Asp Tyr Leu Tyr Gly Gln Thr Thr
                 680                 685                 690

 Thr Tyr Leu Thr Tyr Asn Asp Phe Ile Asn Lys Glu Leu Ile Leu
                 695                 700                 705

 Phe Ser Asn Ser Asp Asn Glu Arg Ser Ile Pro Ser Met Val Asp
                 710                 715                 720

 Gly Leu Lys Pro Gly Gln Arg Lys Val Leu Phe Thr Cys Phe Lys
                 725                 730                 735

 Arg Asn Asp Lys Arg Glu Val Lys Val Ala Gln Leu Ala Gly Ser
                 740                 745                 750

 Val Ala Glu Met Ser Ser Tyr His His Gly Glu Met Ser Leu Met
                 755                 760                 765

 Met Thr Ile Ile Asn Leu Ala Gln Asn Phe Val Gly Ser Asn Asn
                 770                 775                 780

 Leu Asn Leu Leu Gln Pro Ile Gly Gln Phe Gly Thr Arg Leu His
                 785                 790                 795

 Gly Gly Lys Asp Ser Ala Ser Pro Arg Tyr Ile Phe Thr Met Leu
                 800                 805                 810

 Ser Ser Leu Ala Arg Leu Leu Phe Pro Pro Lys Asp Asp His Thr
                 815                 820                 825

 Leu Lys Phe Leu Tyr Asp Asp Asn Gln Arg Val Glu Pro Glu Trp
                 830                 835                 840

 Tyr Ile Pro Ile Ile Pro Met Val Leu Ile Asn Gly Ala Glu Gly
                 845                 850                 855

 Ile Gly Thr Gly Trp Ser Cys Lys Ile Pro Asn Phe Asp Val Arg
                 860                 865                 870

 Glu Ile Val Asn Asn Ile Arg Arg Leu Met Asp Gly Glu Glu Pro
                 875                 880                 885

 Leu Pro Met Leu Pro Ser Tyr Lys Asn Phe Lys Gly Thr Ile Glu
                 890                 895                 900

 Glu Leu Ala Pro Asn Gln Tyr Val Ile Ser Gly Glu Val Ala Ile
                 905                 910                 915

 Leu Asn Ser Thr Thr Ile Glu Ile Ser Glu Leu Pro Val Arg Thr
                 920                 925                 930

 Trp Thr Gln Thr Tyr Lys Glu Gln Val Leu Glu Pro Met Leu Asn
                 935                 940                 945

 Gly Thr Glu Lys Thr Pro Pro Leu Ile Thr Asp Tyr Arg Glu Tyr
                 950                 955                 960

 His Thr Asp Thr Thr Val Lys Phe Val Val Lys Met Thr Glu Glu
                 965                 970                 975

 Lys Leu Ala Glu Ala Glu Arg Val Gly Leu His Lys Val Phe Lys
                 980                 985                 990

 Leu Gln Thr Ser Leu Thr Cys Asn Ser Met Val Leu Phe Asp His
                 995                1000                1005

 Val Gly Cys Leu Lys Lys Tyr Asp Thr Val Leu Asp Ile Leu Arg
                1010                1015                1020

 Asp Phe Phe Glu Leu Arg Leu Lys Tyr Tyr Gly Leu Arg Lys Glu
                1025                1030                1035

 Trp Leu Leu Gly Met Leu Gly Ala Glu Ser Ala Lys Leu Asn Asn
                1040                1045                1050

 Gln Ala Arg Phe Ile Leu Glu Lys Ile Asp Gly Lys Ile Ile Ile
                1055                1060                1065

 Glu Asn Lys Pro Lys Lys Glu Leu Ile Lys Val Leu Ile Gln Arg
                1070                1075                1080

 Gly Tyr Asp Ser Asp Pro Val Lys Ala Trp Lys Glu Ala Gln Gln
                1085                1090                1095

 Lys Val Pro Asp Glu Glu Glu Asn Glu Glu Ser Asp Asn Glu Lys
                1100                1105                1110

 Glu Thr Glu Lys Ser Asp Ser Val Thr Asp Ser Gly Pro Thr Phe
                1115                1120                1125

 Asn Tyr Leu Leu Asp Met Pro Leu Trp Tyr Leu Thr Lys Glu Lys
                1130                1135                1140

 Lys Asp Glu Leu Cys Arg Leu Arg Asn Glu Lys Glu Gln Glu Leu
                1145                1150                1155

 Asp Thr Leu Lys Arg Lys Ser Pro Ser Asp Leu Trp Lys Glu Asp
                1160                1165                1170

 Leu Ala Thr Phe Ile Glu Glu Leu Glu Ala Val Glu Ala Lys Glu
                1175                1180                1185

 Lys Gln Asp Glu Gln Val Gly Leu Pro Gly Lys Gly Gly Lys Ala
                1190                1195                1200

 Lys Gly Lys Lys Thr Gln Met Ala Glu Val Leu Pro Ser Pro Arg
                1205                1210                1215

 Gly Gln Arg Val Ile Pro Arg Ile Thr Ile Glu Met Lys Ala Glu
                1220                1225                1230

 Ala Glu Lys Lys Asn Lys Lys Lys Ile Lys Asn Glu Asn Thr Glu
                1235                1240                1245

 Gly Ser Pro Gln Glu Asp Gly Val Glu Leu Glu Gly Leu Lys Gln
                1250                1255                1260

 Arg Leu Glu Lys Lys Gln Lys Arg Glu Pro Gly Thr Lys Thr Lys
                1265                1270                1275

 Lys Gln Thr Thr Leu Ala Phe Lys Pro Ile Lys Lys Gly Lys Lys
                1280                1285                1290

 Arg Asn Pro Trp Ser Asp Ser Glu Ser Asp Arg Ser Ser Asp Glu
                1295                1300                1305

 Ser Asn Phe Asp Val Pro Pro Arg Glu Thr Glu Pro Arg Arg Ala
                1310                1315                1320

 Ala Thr Lys Thr Lys Phe Thr Met Asp Leu Asp Ser Asp Glu Asp
                1325                1330                1335

 Phe Ser Asp Phe Asp Glu Lys Thr Asp Asp Glu Asp Phe Val Pro
                1340                1345                1350

 Ser Asp Ala Ser Pro Pro Lys Thr Lys Thr Ser Pro Lys Leu Ser
                1355                1360                1365

 Asn Lys Glu Leu Lys Pro Gln Lys Ser Val Val Ser Asp Leu Glu
                1370                1375                1380

 Ala Asp Asp Val Lys Gly Ser Val Pro Leu Ser Ser Ser Pro Pro
                1385                1390                1395

 Ala Thr His Phe Pro Asp Glu Thr Glu Ile Thr Asn Pro Val Pro
                1400                1405                1410

 Lys Lys Asn Val Thr Val Lys Lys Thr Ala Ala Lys Ser Gln Ser
                1415                1420                1425

 Ser Thr Ser Thr Thr Gly Ala Lys Lys Arg Ala Ala Pro Lys Gly
                1430                1435                1440

 Thr Lys Arg Asp Pro Ala Leu Asn Ser Gly Val Ser Gln Lys Pro
                1445                1450                1455

 Asp Pro Ala Lys Thr Lys Asn Arg Arg Lys Arg Lys Pro Ser Thr
                1460                1465                1470

 Ser Asp Asp Ser Asp Ser Asn Phe Glu Lys Ile Val Ser Lys Ala
                1475                1480                1485

 Val Thr Ser Lys Lys Ser Lys Gly Glu Ser Asp Asp Phe His Met
                1490                1495                1500

 Asp Phe Asp Ser Ala Val Ala Pro Arg Ala Lys Ser Val Arg Ala
                1505                1510                1515

 Lys Lys Pro Ile Lys Tyr Leu Glu Glu Ser Asp Glu Asp Asp Leu
                1520                1525                1530

 Phe


<210> 277
<211> 4243
<212> DNA
<213> Homo sapien

<400> 277
 agatatctcc ggcgccgccc gccattttga ctccagtgtc tcgtttgcag 50

 tcggcgcttt aggggaactg tcttcctccg caggcgcgag gctgggtaca 100

 gggtctattg tctgtggttg actccgtact ttggtctgag gccttcggga 150

 gctttcccga ggcagttagc agaagccgca gcggccgccc ccgcccgtct 200

 cctctgtccc tgggcccggg agggaccaac ttggcgtcac gcccctcagc 250

 ggtcgccact ctcttctctg ttgttgggtc cgcatcgtat tcccggaatc 300

 agacggtgcc ccatagatgg ccagctttcc cccgagggtc aacgagaaag 350

 agatcgtgag attacgtact ataggtgaac ttttagctcc tgcagctcct 400

 tttgacaaga aatgtggtcg tgaaaattgg actgttgctt ttgctccaga 450

 tggttcatac tttgcttggt cacaaggaca tcgcacagta aagcttgttc 500

 cgtggtccca gtgccttcag aactttctct tgcatggcac caagaatgtt 550

 accaattcaa gcagtttaag attgccaaga caaaatagtg atggtggtca 600

 gaaaaataag cctcgtgaac atattataga ctgtggagat atagtctgga 650

 gtcttgcttt tgggtcatca gttccagaaa aacagagtcg ctgtgtaaat 700

 atagaatggc atcgcttcag atttggacaa gatcagctac ttcttgctac 750

 agggttgaac aatgggcgta tcaaaatatg ggatgtatat acaggaaaac 800

 tcctccttaa cttggtagat catactgaag tggtcagaga tttaactttt 850

 gctccagatg gaagcttgat cctggtgtca gcttcaagag acaaaactct 900

 cagagtatgg gacctgaaag atgatggaaa catgatgaaa gtattgaggg 950

 ggcatcagaa ttgggtgtac agctgtgcat tctctcctga ctcttctatg 1000

 ctgtgttcag tcggagccag taaagcagtg gtggcagcaa tattggtgtg 1050

 attgaggtta tgctggcacc actcgcacac aggcgcacaa tggtgttagc 1100

 tgggcagaaa gagtggcatc tctggctacc gggctggggg cgacctttac 1150

 cataggatga agtaaccttg cattcggctg caaggtgtac tgtacgtaca 1200

 caggtgctgg tcgatgtcca ctttctgctt ttctttcttt ctttttttct 1250

 tttttaaagt aatttccccc acagtaaaat acactgactc ctgagtaaat 1300

 tgattttcca gttttatgga attgggagtc tgacaagtga aaccaattta 1350

 atgtaaagta tttggctttc aaatggtttc tctgtgctat tttttggaat 1400

 tctttcagat tccagagata tcttacgtct ttgattcaat ttaaaatttg 1450

 tacttatttt cttttagaaa taatgtattg tgtctgtgca gaaaaaaaaa 1500

 aaaccaaaaa ggattgcttt actccaagag gagagattgt cttaggataa 1550

 acctccaagc tcacatttaa tataacagac tgaagtaaac attagaatcc 1600

 tgtttagagc tattctgcac agttaactac tgatctttag aatctaaaat 1650

 tgtatatgaa cttattctta aataattgaa ccgttttata ttcaaatgac 1700

 ttatgatcgt ggttagtttg ggaaaaataa gatggttaaa ttttgattta 1750

 ttgaaatgta attgtattat tttcataaaa tagcattttc attttgtaat 1800

 gtggtttaac atccttgttg tttgccaaag aaatttcatt tggctgtgaa 1850

 tattctattt gcttgcagta tctgtttctc ttcctaggct caagttggtg 1900

 acccaagcct attgtaaaca agtgattatc tcaaagggag atgccaatgg 1950

 agtaacaatt tgttaacctt acgttttctg tctgtatatt tttttaaaaa 2000

 tctggtagtt tctggaaaaa aaagagaagg gggtttgtag tacttaaccc 2050

 tatttatttc cgtatatttt agttaattag tttttggaat aaatggattt 2100

 cagtatagct ttgtggttaa attgcattgc ctttatttta tgtttaggct 2150

 tatttttaaa ttaacattta acagaaacat ttgaaataga atttgcatgt 2200

 ctgccttaat taacttaaag actgatttta atctgactat gacactgagc 2250

 atattcttta aattactcat aatttataat gcttaatata atcttaatta 2300

 aatttagcag ttttagtata agatgtgcca ttttgtcctc tgtatgtctg 2350

 aatgaagcta taacatttgc ctttttattg caggttttcc tttggaatat 2400

 ggataaatac accatgatac ggaaactaga aggacatcac catgatgtgg 2450

 tagcttgtga cttttctcct gatggagcat tactggctac tgcatcttat 2500

 gatactcgag tatatatctg ggatccacat aatggagaca ttctgatgga 2550

 atttgggcac ctgtttcccc cacctactcc aatatttgct ggaggagcaa 2600

 atgaccggtg ggtacgatct gtatctttta gccatgatgg actgcatgtt 2650

 gcaagccttg ctgatgataa aatggtgagg ttctggagaa ttgatgagga 2700

 ttatccagtg caagttgcac ctttgagcaa tggtctttgc tgtgccttct 2750

 ctactgatgg cagtgtttta gctgctggga cacatgacgg aagtgtgtat 2800

 ttttgggcca ctccacggca ggtccctagc ctgcaacatt tatgtcgcat 2850

 gtcaatccga agagtgatgc ccacccaaga agttcaggag ctgccgattc 2900

 cttccaagct tttggagttt ctctcgtatc gtatttagaa gattctgcct 2950

 tccctagtag tagggactga cagaatacac ttaacacaaa cctcaagctt 3000

 tactgacttc aattatctgt ttttaaagac gtagaagatt tatttaattt 3050

 gatatgttct tgtactgcat tttgatcagt tgagctttta aaatattatt 3100

 tatagacaat agaagtattt ctgaacatat caaatataaa tttttttaaa 3150

 gatctaactg tgaaaacata catacctgta catatttaga tataagctgc 3200

 tatatgttga atggaccctt ttgcttttct gatttttagt tctgacatgt 3250

 atatattgct tcagtagagc cacaatatgt atctttgctg taaagtgcaa 3300

 ggaaatttta aattctggga cactgagtta gatggtaaat actgacttac 3350

 gaaagttgaa ttgggtgagg cgggcaaatc acctgaggtc agcagtttga 3400

 gactagcctg gcaaacatga tgaaaccctg tctctactaa aaatacaaaa 3450

 aaaaaaaaaa ttagccaggc gtggtggtgc acacctgtag tcctagctac 3500

 ttgggaggct gaggcaggag aattgcttga acccaggagg tggaggttgc 3550

 agtaagccaa gatcacacca ctgcactcca acctggacaa cagagcgaga 3600

 ctccatctca aaaaaaaaaa aaaattgtgt tgcctcatac gaaatgtatt 3650

 tggttttgtt ggagagtgtc agactgatct ggaagtgaaa cacagtttat 3700

 gtacagggaa aaggatttta ttatccttag gaatgtcatc caagacgtag 3750

 agcttgaatg tgacgttatt taaaaacaac aacaaagaag gcagagccag 3800

 gatataacta gaaaaaggat gtcttttttt ttttttttac tccccctcta 3850

 aacactgctg ctgccttaat tttagaaagc agcttactag tttacccttg 3900

 tggtataaag tattataaat tgttgtgaat ttgaagaatc cgtctactgt 3950

 attattgcta aatattttgt ttatactaag ggacaattat tttaagacca 4000

 tggatttaaa aaaaaaaaaa aaaactctgt ttctgcaggg gatgatattg 4050

 gtgagttgcc aaagaagcaa tacagcatat ctgcttttgc cttctgttgt 4100

 ttatcttacc tgcagatatt aagaatgtat gcattatgta aaatgctcaa 4150

 ttatatattt ttgttgagtt ttttaattaa agacttgtaa aaaaaaaaaa 4200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 4243

<210> 278
<211> 244
<212> PRT
<213> Homo sapien

<400> 278
 Met Ala Ser Phe Pro Pro Arg Val Asn Glu Lys Glu Ile Val Arg
   1               5                  10                  15

 Leu Arg Thr Ile Gly Glu Leu Leu Ala Pro Ala Ala Pro Phe Asp
                  20                  25                  30

 Lys Lys Cys Gly Arg Glu Asn Trp Thr Val Ala Phe Ala Pro Asp
                  35                  40                  45

 Gly Ser Tyr Phe Ala Trp Ser Gln Gly His Arg Thr Val Lys Leu
                  50                  55                  60

 Val Pro Trp Ser Gln Cys Leu Gln Asn Phe Leu Leu His Gly Thr
                  65                  70                  75

 Lys Asn Val Thr Asn Ser Ser Ser Leu Arg Leu Pro Arg Gln Asn
                  80                  85                  90

 Ser Asp Gly Gly Gln Lys Asn Lys Pro Arg Glu His Ile Ile Asp
                  95                 100                 105

 Cys Gly Asp Ile Val Trp Ser Leu Ala Phe Gly Ser Ser Val Pro
                 110                 115                 120

 Glu Lys Gln Ser Arg Cys Val Asn Ile Glu Trp His Arg Phe Arg
                 125                 130                 135

 Phe Gly Gln Asp Gln Leu Leu Leu Ala Thr Gly Leu Asn Asn Gly
                 140                 145                 150

 Arg Ile Lys Ile Trp Asp Val Tyr Thr Gly Lys Leu Leu Leu Asn
                 155                 160                 165

 Leu Val Asp His Thr Glu Val Val Arg Asp Leu Thr Phe Ala Pro
                 170                 175                 180

 Asp Gly Ser Leu Ile Leu Val Ser Ala Ser Arg Asp Lys Thr Leu
                 185                 190                 195

 Arg Val Trp Asp Leu Lys Asp Asp Gly Asn Met Met Lys Val Leu
                 200                 205                 210

 Arg Gly His Gln Asn Trp Val Tyr Ser Cys Ala Phe Ser Pro Asp
                 215                 220                 225

 Ser Ser Met Leu Cys Ser Val Gly Ala Ser Lys Ala Val Val Ala
                 230                 235                 240

 Ala Ile Leu Val


<210> 279
<211> 4212
<212> DNA
<213> Homo sapien

<400> 279
 gggcagtgtc tcgtttgcag tcggcgcttt aggggaactg tcttcctccg 50

 caggcgcgag gctgggtaca gggtctattg tctgtggttg actccgtact 100

 ttggtctgag gccttcggga gctttcccga ggcagttagc agaagccgca 150

 gcggccgccc ccgcccgtct cctctgtccc tgggcccggg agggaccaac 200

 ttggcgtcac gcccctcagc ggtcgccact ctcttctctg ttgttgggtc 250

 cgcatcgtat tcccggaatc agacggtgcc ccatagatgg ccagctttcc 300

 cccgagggtc aacgagaaag agatcgtgag attacgtact ataggtgaac 350

 ttttagctcc tgcagctcct tttgacaaga aatgtggtcg tgaaaattgg 400

 actgttgctt ttgctccaga tggttcatac tttgcttggt cacaaggaca 450

 tcgcacagta aagcttgttc cgtggtccca gtgccttcag aactttctct 500

 tgcatggcac caagaatgtt accaattcaa gcagtttaag attgccaaga 550

 caaaatagtg atggtggtca gaaaaataag cctcgtgaac atattataga 600

 ctgtggagat atagtctgga gtcttgcttt tgggtcatca gttccagaaa 650

 aacagagtcg ctgtgtaaat atagaatggc atcgcttcag atttggacaa 700

 gatcagctac ttcttgctac agggttgaac agtgggcgta tcaaaatatg 750

 ggatgtatat acaggaaaac tcctccttaa cttggtagat catactggag 800

 tggtcagaga tttaactttt gctccagatg gaagcttgat cctggtgtca 850

 gcttcaagag acaaaactct cagagtatgg gacctgagag atgatggaaa 900

 catgatgaaa gtattgaggg ggcatcagaa ttgggtgtac agctgtgcat 950

 tctctcctga ctcttctatg ctgtgttcag tcggagccag taaagcagtg 1000

 gtggcagcaa tattggtgtg attgaggtta tgctggcacc actcgcacac 1050

 aggcgcacaa tggtgttagc tgggcagaaa gagtggcatc tctggctacc 1100

 gggctggggg cgacctttac cataggatga agtaaccttg cattcggctg 1150

 caaggtgtac tgtacgtaca caggtgctgg tcgatgtcca ctttctgctt 1200

 ttctttcttt ctttttttct tttttaaagt aatttccccc acagtaaaat 1250

 acactgactc ctgagtaaat tgattttcca gttttatgga attgggagtc 1300

 tgacaagtga aaccaattta atgtaaagta tttggctttc aaatggtttc 1350

 tctgtgctat tttttggaat tctttcagat tccagagata tcttacgtct 1400

 ttgattcaat ttaaaatttg tacttatttt cttttagaaa taatgtattg 1450

 tgtctgtgca gaaaaaaaaa aaaccaaaaa ggattgcttt actccaagag 1500

 gagagattgt cttaggataa acctccaagc tcacatttaa tataacagac 1550

 tgaagtaaac attagaatcc tgtttagagc tattctgcac agttaactac 1600

 tgatctttag aatctaaaat tgtatatgaa cttattctta aataattgaa 1650

 ctgttttata ttcaaatgac ttatgatcgt ggttagtttg ggaaaaataa 1700

 gatggttaaa ttttgattta ttgaaatgta attgtattat tttcataaaa 1750

 tagcattttc attttgtaat gtggtttaac atccttgttg tttgccaaag 1800

 aaatttcatt tggctgtgaa tattctattt gcttgcagta tctgtttctc 1850

 ttcctaggct caagttggtg acccaagcct attgtaaaca agtgattatc 1900

 tcaaagggag atgccaatgg agtaacaatt tgttaacctt acgttttctg 1950

 tctgtatatt ttttaaaaat ctggtagttt ctggaaaaaa aaagagaagg 2000

 gggtttgtag tacttaaccc tatttatttc cgtatatttt agttaattag 2050

 tttttggaat aaatggattt cagtatagct ttgtggttaa attgcattgc 2100

 ctttatttta tgtttaggct tatttttaaa ttaacattta acagaaacat 2150

 ttgaaataga atttgcatgt ctgccttaat taacttaaag actgatttta 2200

 atctgactat gacactgagc atattcttta aattactcat aatttataat 2250

 gcttaatata atcttaatta aatttagcag ttttagtata agatgtgcca 2300

 ttttgtcctc tgtatgtctg aatgaagcta taacattcgc ctttttattg 2350

 caggttttcc tttggaatat ggataaatac accatgatgc ggaaactaga 2400

 aggacatcac catgatgtgg tagcttgtga cttttctcct gatggagcat 2450

 tactggctac tgcatcttat gatacttgag tatatatctg ggatccacat 2500

 aatggagaca ttctgatgga atttgggcac ctgtttcccc cacctactcc 2550

 aatatttgct ggaggagcaa atgaccggtg ggtacgatct gtatctttta 2600

 gccatgatgg actgcatgtt gcaagccttg ctgatgataa aatgggtgag 2650

 gttctggaga attgatgagg attatccagt gcaagttgca cctgtgagca 2700

 atggtctttg ctgtgccttc tctactgatg gcagtgtttt agctgctggg 2750

 acacatgacg gaagtgtgta tttttgggcc actccacggc aggtccctag 2800

 cctgcaacat ttatgtcgca tgtcaatccg aagagtgatg cccacccaag 2850

 aagttcagga gctgccgatt ccttccaagc ttttggagtt tctctcgtat 2900

 cgtatttaga agattctgcc ttccctagta gtagggactg acagaataca 2950

 cttaacacaa acctcaagct ttactgactt caattatctg tttttaaaga 3000

 cgtagaagat ttatttaatt tgatatgttc ttgtactgca ttttgatcag 3050

 ttgagctttt aaaatattat ttatagacaa tagaagtatt tctgaacata 3100

 tcaaatataa atttttttaa agatctaact gtgaaaacat acatacctgt 3150

 acatatttag atataagctg ctatatgttg aatggaccct tttgcttttc 3200

 tgatttttag ttctgacatg tatatattgc ttcagtagag ccacaatatg 3250

 tatctttgct gtaaagtgca aggaaatttt aaattctggg acactgagtt 3300

 agatggtaaa tactgactta cgaaagttga attgggtgag gcgggcaaat 3350

 cacctgaggt cagcagtttg agactagcct ggcaaacatg atgaaaccct 3400

 gtctctacta aaaatacaaa aaaaaaaaaa ttagccaggc gtggtggtgc 3450

 acacctgtag tcctagctac ttgggaggct gaggcaggag aattgcttga 3500

 acccaggagg tggaggttgc agtaagccaa gatcacacca ctgcactcca 3550

 acctggacaa cagagcgaga ctccatctca aaaaaaaaaa aaaattgtgt 3600

 tgcctcatac gaaatgtatt tggttttgtt ggagagtgtc agactgatct 3650

 ggaagtgaaa cacagtttat gtacagggaa aaggatttta ttatccttag 3700

 gaatgtcatc caagacgtag agcttgaatg tgacgttatt taaaaacaac 3750

 aacaaagaag gcagagccag gatataacta gaaaaaggat gtcttttttt 3800

 tttttttact ccccctctaa acactgctgc tgccttaatt ttagaaagca 3850

 gcttactagt ttacccttgt ggtataaagt attataaatt gttgtgaatt 3900

 tgaagaatcc gtctactgta ttattgctaa atattttgtt tatactaagg 3950

 gacaattatt ttaagaccat ggatttaaag aaaaaaaaaa aaactctgtt 4000

 tctgcagggg atgatattgg tgagttgcca aagaagcaat acagcatatc 4050

 tgcttttgcc ttctgttgtt tatcttacct gcagatatta agaatgtatg 4100

 cattatgtaa aatgctcaat tatatatttt tgttgagttt tttaattaaa 4150

 gacttgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4200

 aaaaaagaaa aa 4212

<210> 280
<211> 112
<212> PRT
<213> Homo sapien

<400> 280
 Met Thr Gly Gly Tyr Asp Leu Tyr Leu Leu Ala Met Met Asp Cys
   1               5                  10                  15

 Met Leu Gln Ala Leu Leu Met Ile Lys Trp Val Arg Phe Trp Arg
                  20                  25                  30

 Ile Asp Glu Asp Tyr Pro Val Gln Val Ala Pro Val Ser Asn Gly
                  35                  40                  45

 Leu Cys Cys Ala Phe Ser Thr Asp Gly Ser Val Leu Ala Ala Gly
                  50                  55                  60

 Thr His Asp Gly Ser Val Tyr Phe Trp Ala Thr Pro Arg Gln Val
                  65                  70                  75

 Pro Ser Leu Gln His Leu Cys Arg Met Ser Ile Arg Arg Val Met
                  80                  85                  90

 Pro Thr Gln Glu Val Gln Glu Leu Pro Ile Pro Ser Lys Leu Leu
                  95                 100                 105

 Glu Phe Leu Ser Tyr Arg Ile
                 110

<210> 281
<211> 1982
<212> DNA
<213> Homo sapien

<400> 281
 gcagaggagg agcgcacgcc ggcctcgaag aacttctgct tgggtggctg 50

 aactctgatc ttgacctaga gtcatggcca tggcaaccaa aggaggtact 100

 gtcaaagctg cttcaggatt caatgccatg gaagatgccc agaccctgag 150

 gaaggccatg aaagggctcg gcaccgatga agacgccatt attagcgtcc 200

 ttgcctaccg caacaccgcc cagcgccagg agatcaggac agcctacaag 250

 agcaccatcg gcagggactt gatagacgac ctgaagtcag aactgagtgg 300

 caacttcgag caggtgattg tggggatgat gacgcccacg gtgctgtatg 350

 acgtgcaaga gctgcgaagg gccatgaagg gagccggcac tgatgagggc 400

 tgcctaattg agatcctggc ctcccggacc cctgaggaga tccggcgcat 450

 aagccaaacc taccagcagc aatatggacg gagccttgaa gatgacattc 500

 gctctgacac atcgttcatg ttccagcgag tgctggtgtc tctgtcagct 550

 ggtgggaggg atgaaggaaa ttatctggac gatgctctcg tgagacagga 600

 tgcccaggac ctgtatgagg ctggagagaa gaaatggggg acagatgagg 650

 tgaaatttct aactgttctc tgttcccgga accgaaatca cctgttgcat 700

 gtgtttgatg aatacaaaag gatatcacag aaggatattg aacagagtat 750

 taaatctgaa acatctggta gctttgaaga tgctctgctg gctatagtaa 800

 agtgcatgag gaacaaatct gcatattttg ctgaaaagct ctataaatcg 850

 atgaagggct tgggcaccga tgataacacc ctcatcagag tgatggtttc 900

 tcgagcagaa attgacatgt tggatatccg ggcacacttc aagagactct 950

 atggaaagtc tctgtactcg ttcatcaagg gtgacacatc tggagactac 1000

 aggaaagtac tgcttgttct ctgtggagga gatgattaaa ataaaaatcc 1050

 cagaaggaca ggaggattct caacactttg aattttttta acttcatttt 1100

 tctacactgc tattatcatt atctcagaat gcttatttcc aattaaaacg 1150

 cctacagctg cctcctagaa tatagactgt ctgtattatt attcacctat 1200

 aattagtcat tatgatgctt taaagctgta cttgcatttc aaagcttata 1250

 agatataaat ggagatttta aagtagaaat aaatatgtat tccatgtttt 1300

 taaaagatta ctttctactt tgtgtttcac agacattgaa tatattaaat 1350

 tattccatat tttcttttca gtgaaaaatt ttttaaatgg aagactgttc 1400

 taaaatcact tttttcccta atccaatttt tagagtggct agtagtttct 1450

 tcatttgaaa ttgtaagcat ccggtcagta agaatgccca tccagttttc 1500

 tatatttcat agtcaaagcc ttgaaagcat ctacaaatct ctttttttag 1550

 gttttgtcca tagcatcagt tgatccttac taagtttttc atgggagact 1600

 tccttcatca catcttatgt tgaaatcact ttctgtagtc aaagtatacc 1650

 aaaaccaatt tatctgaact aaattctaaa gtatggttat acaaaccata 1700

 tacatctggt taccaaacat aaatgctgaa cattccatat tattatagtt 1750

 aatgtcttaa tccagcttgc aagtgaatgg aaaaaaaaat aagcttcaaa 1800

 ctaggtattc tgggaatgat gtaatgctct gaatttagta tgatataaag 1850

 aaaacttttt tgtgctaaaa atacttttta aaatcaattt tgttgattgt 1900

 agtaatttct atttgcactg tgcctttcaa ctccagaaac attctaagat 1950

 gtacttggat ttaattaaaa agttcacttt gt 1982

<210> 282
<211> 321
<212> PRT
<213> Homo sapien

<400> 282
 Met Ala Met Ala Thr Lys Gly Gly Thr Val Lys Ala Ala Ser Gly
   1               5                  10                  15

 Phe Asn Ala Met Glu Asp Ala Gln Thr Leu Arg Lys Ala Met Lys
                  20                  25                  30

 Gly Leu Gly Thr Asp Glu Asp Ala Ile Ile Ser Val Leu Ala Tyr
                  35                  40                  45

 Arg Asn Thr Ala Gln Arg Gln Glu Ile Arg Thr Ala Tyr Lys Ser
                  50                  55                  60

 Thr Ile Gly Arg Asp Leu Ile Asp Asp Leu Lys Ser Glu Leu Ser
                  65                  70                  75

 Gly Asn Phe Glu Gln Val Ile Val Gly Met Met Thr Pro Thr Val
                  80                  85                  90

 Leu Tyr Asp Val Gln Glu Leu Arg Arg Ala Met Lys Gly Ala Gly
                  95                 100                 105

 Thr Asp Glu Gly Cys Leu Ile Glu Ile Leu Ala Ser Arg Thr Pro
                 110                 115                 120

 Glu Glu Ile Arg Arg Ile Ser Gln Thr Tyr Gln Gln Gln Tyr Gly
                 125                 130                 135

 Arg Ser Leu Glu Asp Asp Ile Arg Ser Asp Thr Ser Phe Met Phe
                 140                 145                 150

 Gln Arg Val Leu Val Ser Leu Ser Ala Gly Gly Arg Asp Glu Gly
                 155                 160                 165

 Asn Tyr Leu Asp Asp Ala Leu Val Arg Gln Asp Ala Gln Asp Leu
                 170                 175                 180

 Tyr Glu Ala Gly Glu Lys Lys Trp Gly Thr Asp Glu Val Lys Phe
                 185                 190                 195

 Leu Thr Val Leu Cys Ser Arg Asn Arg Asn His Leu Leu His Val
                 200                 205                 210

 Phe Asp Glu Tyr Lys Arg Ile Ser Gln Lys Asp Ile Glu Gln Ser
                 215                 220                 225

 Ile Lys Ser Glu Thr Ser Gly Ser Phe Glu Asp Ala Leu Leu Ala
                 230                 235                 240

 Ile Val Lys Cys Met Arg Asn Lys Ser Ala Tyr Phe Ala Glu Lys
                 245                 250                 255

 Leu Tyr Lys Ser Met Lys Gly Leu Gly Thr Asp Asp Asn Thr Leu
                 260                 265                 270

 Ile Arg Val Met Val Ser Arg Ala Glu Ile Asp Met Leu Asp Ile
                 275                 280                 285

 Arg Ala His Phe Lys Arg Leu Tyr Gly Lys Ser Leu Tyr Ser Phe
                 290                 295                 300

 Ile Lys Gly Asp Thr Ser Gly Asp Tyr Arg Lys Val Leu Leu Val
                 305                 310                 315

 Leu Cys Gly Gly Asp Asp
                 320

<210> 283
<211> 1982
<212> DNA
<213> Homo sapien

<400> 283
 gcagaggagg agcgcacgcc ggcctcgaag aacttctgct tgggtggctg 50

 aactctgatc ttgacctaga gtcatggcca tggcaaccaa aggaggtact 100

 gtcaaagctg cttcaggatt caatgccatg gaagatgccc agaccctgag 150

 gaaggccatg aaagggctcg gcaccgatga agacgccatt attagcgtcc 200

 ttgcctaccg caacaccgcc cagcgccagg agatcaggac agcctacaag 250

 agcaccatcg gcagggactt gatagacgac ctgaagtcag aactgagtgg 300

 caacttcgag caggtgattg tggggatgat gacgcccacg gtgctgtatg 350

 acgtgcaaga gctgcgaagg gccatgaagg gagccggcac tgatgagggc 400

 tgcctaattg agatcctggc ctcccggacc cctgaggaga tccggcgcat 450

 aagccaaacc taccagcagc aatatggacg gagccttgaa gatgacattc 500

 gctctgacac atcgttcatg ttccagcgag tgctggtgtc tctgtcagct 550

 ggtgggaggg atgaaggaaa ttatctggac gatgctctcg tgagacagga 600

 tgcccaggac ctgtatgagg ctggagagaa gaaatggggg acagatgagg 650

 tgaaatttct aactgttctc tgttcccgga accgaaatca cctgttgcat 700

 gtgtttgatg aatacaaaag gatatcacag aaggatattg aacagagtat 750

 taaatctgaa acatctggta gctttgaaga tgctctgctg gctatagtaa 800

 agtgcatgag gaacaaatct gcatattttg ctgaaaagct ctataaatcg 850

 atgaagggct tgggcaccga tgataacacc ctcatcagag tgatggtttc 900

 tcgagcagaa attgacatgt tggatatccg ggcacacttc aagagactct 950

 atggaaagtc tctgtactcg ttcatcaagg gtgacacatc tggagactac 1000

 aggaaagtac tgcttgttct ctgtggagga gatgattaaa ataaaaatcc 1050

 cagaaggaca ggaggattct caacactttg aattttttta acttcatttt 1100

 tctacactgc tattatcatt atctcagaat gcttatttcc aattaaaacg 1150

 cctacagctg cctcctagaa tatagactgt ctgtattatt attcacctat 1200

 aattagtcat tatgatgctt taaagctgta cttgcatttc aaagcttata 1250

 agatataaat ggagatttta aagtagaaat aaatatgtat tccatgtttt 1300

 taaaagatta ctttctactt tgtgtttcac agacattgaa tatattaaat 1350

 tattccatat tttcttttca gtgaaaaatt ttttaaatgg aagactgttc 1400

 taaaatcact tttttcccta atccaatttt tagagtggct agtagtttct 1450

 tcatttgaaa ttgtaagcat ccggtcagta agaatgccca tccagttttc 1500

 tatatttcat agtcaaagcc ttgaaagcat ctacaaatct ctttttttag 1550

 gttttgtcca tagcatcagt tgatccttac taagtttttc atgggagact 1600

 tccttcatca catcttatgt tgaaatcact ttctgtagtc aaagtatacc 1650

 aaaaccaatt tatctgaact aaattctaaa gtatggttat acaaaccata 1700

 tacatctggt taccaaacat aaatgctgaa cattccatat tattatagtt 1750

 aatgtcttaa tccagcttgc aagtgaatgg aaaaaaaaat aagcttcaaa 1800

 ctaggtattc tgggaatgat gtaatgctct gaatttagta tgatataaag 1850

 aaaacttttt tgtgctaaaa atacttttta aaatcaattt tgttgattgt 1900

 agtaatttct atttgcactg tgcctttcaa ctccagaaac attctaagat 1950

 gtacttggat ttaattaaaa agttcacttt gt 1982

<210> 284
<211> 321
<212> PRT
<213> Homo sapien

<400> 284
 Met Ala Met Ala Thr Lys Gly Gly Thr Val Lys Ala Ala Ser Gly
   1               5                  10                  15

 Phe Asn Ala Met Glu Asp Ala Gln Thr Leu Arg Lys Ala Met Lys
                  20                  25                  30

 Gly Leu Gly Thr Asp Glu Asp Ala Ile Ile Ser Val Leu Ala Tyr
                  35                  40                  45

 Arg Asn Thr Ala Gln Arg Gln Glu Ile Arg Thr Ala Tyr Lys Ser
                  50                  55                  60

 Thr Ile Gly Arg Asp Leu Ile Asp Asp Leu Lys Ser Glu Leu Ser
                  65                  70                  75

 Gly Asn Phe Glu Gln Val Ile Val Gly Met Met Thr Pro Thr Val
                  80                  85                  90

 Leu Tyr Asp Val Gln Glu Leu Arg Arg Ala Met Lys Gly Ala Gly
                  95                 100                 105

 Thr Asp Glu Gly Cys Leu Ile Glu Ile Leu Ala Ser Arg Thr Pro
                 110                 115                 120

 Glu Glu Ile Arg Arg Ile Ser Gln Thr Tyr Gln Gln Gln Tyr Gly
                 125                 130                 135

 Arg Ser Leu Glu Asp Asp Ile Arg Ser Asp Thr Ser Phe Met Phe
                 140                 145                 150

 Gln Arg Val Leu Val Ser Leu Ser Ala Gly Gly Arg Asp Glu Gly
                 155                 160                 165

 Asn Tyr Leu Asp Asp Ala Leu Val Arg Gln Asp Ala Gln Asp Leu
                 170                 175                 180

 Tyr Glu Ala Gly Glu Lys Lys Trp Gly Thr Asp Glu Val Lys Phe
                 185                 190                 195

 Leu Thr Val Leu Cys Ser Arg Asn Arg Asn His Leu Leu His Val
                 200                 205                 210

 Phe Asp Glu Tyr Lys Arg Ile Ser Gln Lys Asp Ile Glu Gln Ser
                 215                 220                 225

 Ile Lys Ser Glu Thr Ser Gly Ser Phe Glu Asp Ala Leu Leu Ala
                 230                 235                 240

 Ile Val Lys Cys Met Arg Asn Lys Ser Ala Tyr Phe Ala Glu Lys
                 245                 250                 255

 Leu Tyr Lys Ser Met Lys Gly Leu Gly Thr Asp Asp Asn Thr Leu
                 260                 265                 270

 Ile Arg Val Met Val Ser Arg Ala Glu Ile Asp Met Leu Asp Ile
                 275                 280                 285

 Arg Ala His Phe Lys Arg Leu Tyr Gly Lys Ser Leu Tyr Ser Phe
                 290                 295                 300

 Ile Lys Gly Asp Thr Ser Gly Asp Tyr Arg Lys Val Leu Leu Val
                 305                 310                 315

 Leu Cys Gly Gly Asp Asp
                 320

<210> 285
<211> 1763
<212> DNA
<213> Homo sapien

<400> 285
 tagctggatt ccagccattg ctgcagctgc tccacagccc ttttcaggac 50

 ccaaacaacc gcagccgctg ttcccaggat ggtgatccgt gtatatattg 100

 catcttcctc tggctctaca gcgattaaga agaaacaaca agatgtgctt 150

 ggtttcctag aagccaacaa aataggattt gaagaaaaag atattgcagc 200

 caatgaagag aatcggaagt ggatgagaga aaatgtacct gaaaatagtc 250

 gaccagccac aggttacccc ctgccacctc agattttcaa tgaaagccag 300

 tatcgcgggg actatgatgc cttctttgaa gccagagaaa ataatgcagt 350

 gtatgccttc ttaggcttga cagccccacc tggttcaaag gaagcagaag 400

 tgcaagcaaa gcagcaagca tgaaccttaa gcactgtgct ttaagcatcc 450

 tgaaaaatga gtctccattg cttttataaa atagcagaat tagctttgct 500

 tcaaaagaaa taggcttaat gttgaaataa tagattagtt gggttttcac 550

 atgcaaacat tcaaaatgaa tacaaaatta aaatttgaac attatggtga 600

 ttatggtgag gagaatggga tattaacata aaattatatt aataagtaga 650

 tatcgtagaa atagtgttgt tacctgccaa gccatcctgt atacaccaat 700

 gattttacaa agaaaacacc cttccctcct tctgccatta ctatggcaac 750

 ttaagtgtat ctgcagctct acattaaaaa ggagaaagag aaataacctg 800

 tctctcattc ctaagttgcc tcattaattt tcatgaacaa gaatatgtac 850

 ctttttgatg ctatattact gcgattaaaa aagttcttgc aggtaatgtt 900

 tatgtatagt taaacgttgt aatttcttat cgtaattata acattcccat 950

 tctttgtaga tgaaactcta catatgaacc acagattttc tgagcttcta 1000

 aatgtagcct ttcattgcac atttcagtga tcagaataga tatcctttta 1050

 cacgcacaaa agcaatagat tcattcagtg gacaagttcc ttgtttaact 1100

 acacagctat gatggaatca tatatccaag ttccttgcct cagtgaaata 1150

 tgcatatgta tatcatgaag tgggatgcca agtaagctta aaatgcattc 1200

 tctagcaaag agattagact tttaaataac tcttataaaa caggttggcg 1250

 atcatttccc aagattggtt tcccttgagt ttttgttaaa acaaatctta 1300

 gtagttttgc ccgtttaaaa caactcacaa tcgtaaatgc tactattcct 1350

 aagatatctt acctttttat ttcagtttag ccatgtattg tatgagtgta 1400

 ttagtctaag cagtgagaat cttttctatg cctctattcc agcaaaaagt 1450

 agaagtatca aataaaaagg gcaactttta aaatattaag cctgaagact 1500

 tctaaaaaga caagaaacat ggcctaaata accaacatag atttacatag 1550

 taagtttcac actaccttat taccaaaagc aaacacctct tactttaaac 1600

 tacattatca tgtatatcta ttgtatgctg gtctttactt tttgccaaaa 1650

 tcaacatata atgaagagat gcctttgttt gatgagattc aaacttgatg 1700

 ctatgcttta aaataaactc agtactttta gaaacataaa aaaaaaaaaa 1750

 aaaaaaaaaa aaa 1763

<210> 286
<211> 114
<212> PRT
<213> Homo sapien

<400> 286
 Met Val Ile Arg Val Tyr Ile Ala Ser Ser Ser Gly Ser Thr Ala
   1               5                  10                  15

 Ile Lys Lys Lys Gln Gln Asp Val Leu Gly Phe Leu Glu Ala Asn
                  20                  25                  30

 Lys Ile Gly Phe Glu Glu Lys Asp Ile Ala Ala Asn Glu Glu Asn
                  35                  40                  45

 Arg Lys Trp Met Arg Glu Asn Val Pro Glu Asn Ser Arg Pro Ala
                  50                  55                  60

 Thr Gly Tyr Pro Leu Pro Pro Gln Ile Phe Asn Glu Ser Gln Tyr
                  65                  70                  75

 Arg Gly Asp Tyr Asp Ala Phe Phe Glu Ala Arg Glu Asn Asn Ala
                  80                  85                  90

 Val Tyr Ala Phe Leu Gly Leu Thr Ala Pro Pro Gly Ser Lys Glu
                  95                 100                 105

 Ala Glu Val Gln Ala Lys Gln Gln Ala
                 110

<210> 287
<211> 1763
<212> DNA
<213> Homo sapien

<400> 287
 tagctggatt ccagccattg ctgcagctgc tccacagccc ttttcaggac 50

 ccaaacaacc gcagccgctg ttcccaggat ggtgatccgt gtatatattg 100

 catcttcctc tggctctaca gcgattaaga agaaacaaca agatgtgctt 150

 ggtttcctag aagccaacaa aataggattt gaagaaaaag atattgcagc 200

 caatgaagag aatcggaagt ggatgagaga aaatgtacct gaaaatagtc 250

 gaccagccac aggttacccc ctgccacctc agattttcaa tgaaagccag 300

 tatcgcgggg actatgatgc cttctttgaa gccagagaaa ataatgcagt 350

 gtatgccttc ttaggcttga cagccccacc tggttcaaag gaagcagaag 400

 tgcaagcaaa gcagcaagca tgaaccttaa gcactgtgct ttaagcatcc 450

 tgaaaaatga gtctccattg cttttataaa atagcagaat tagctttgct 500

 tcaaaagaaa taggcttaat gttgaaataa tagattagtt gggttttcac 550

 atgcaaacat tcaaaatgaa tacaaaatta aaatttgaac attatggtga 600

 ttatggtgag gagaatggga tattaacata aaattatatt aataagtaga 650

 tatcgtagaa atagtgttgt tacctgccaa gccatcctgt atacaccaat 700

 gattttacaa agaaaacacc cttccctcct tctgccatta ctatggcaac 750

 ttaagtgtat ctgcagctct acattaaaaa ggagaaagag aaataacctg 800

 tctctcattc ctaagttgcc tcattaattt tcatgaacaa gaatatgtac 850

 ctttttgatg ctatattact gcgattaaaa aagttcttgc aggtaatgtt 900

 tatgtatagt taaacgttgt aatttcttat cgtaattata acattcccat 950

 tctttgtaga tgaaactcta catatgaacc acagattttc tgagcttcta 1000

 aatgtagcct ttcattgcac atttcagtga tcagaataga tatcctttta 1050

 cacgcacaaa agcaatagat tcattcagtg gacaagttcc ttgtttaact 1100

 acacagctat gatggaatca tatatccaag ttccttgcct cagtgaaata 1150

 tgcatatgta tatcatgaag tgggatgcca agtaagctta aaatgcattc 1200

 tctagcaaag agattagact tttaaataac tcttataaaa caggttggcg 1250

 atcatttccc aagattggtt tcccttgagt ttttgttaaa acaaatctta 1300

 gtagttttgc ccgtttaaaa caactcacaa tcgtaaatgc tactattcct 1350

 aagatatctt acctttttat ttcagtttag ccatgtattg tatgagtgta 1400

 ttagtctaag cagtgagaat cttttctatg cctctattcc agcaaaaagt 1450

 agaagtatca aataaaaagg gcaactttta aaatattaag cctgaagact 1500

 tctaaaaaga caagaaacat ggcctaaata accaacatag atttacatag 1550

 taagtttcac actaccttat taccaaaagc aaacacctct tactttaaac 1600

 tacattatca tgtatatcta ttgtatgctg gtctttactt tttgccaaaa 1650

 tcaacatata atgaagagat gcctttgttt gatgagattc aaacttgatg 1700

 ctatgcttta aaataaactc agtactttta gaaacataaa aaaaaaaaaa 1750

 aaaaaaaaaa aaa 1763

<210> 288
<211> 114
<212> PRT
<213> Homo sapien

<400> 288
 Met Val Ile Arg Val Tyr Ile Ala Ser Ser Ser Gly Ser Thr Ala
   1               5                  10                  15

 Ile Lys Lys Lys Gln Gln Asp Val Leu Gly Phe Leu Glu Ala Asn
                  20                  25                  30

 Lys Ile Gly Phe Glu Glu Lys Asp Ile Ala Ala Asn Glu Glu Asn
                  35                  40                  45

 Arg Lys Trp Met Arg Glu Asn Val Pro Glu Asn Ser Arg Pro Ala
                  50                  55                  60

 Thr Gly Tyr Pro Leu Pro Pro Gln Ile Phe Asn Glu Ser Gln Tyr
                  65                  70                  75

 Arg Gly Asp Tyr Asp Ala Phe Phe Glu Ala Arg Glu Asn Asn Ala
                  80                  85                  90

 Val Tyr Ala Phe Leu Gly Leu Thr Ala Pro Pro Gly Ser Lys Glu
                  95                 100                 105

 Ala Glu Val Gln Ala Lys Gln Gln Ala
                 110

<210> 289
<211> 905
<212> DNA
<213> Homo sapien

<400> 289
 caacacaggg gcagtctcca ggacctccac accattaaca agatgagcct 50

 tgtgctccct tgggctctag agaggaagcc cctctgagcc ctcagcccct 100

 ctttcctccc tctcctaaag taatttgatc ctcaggaatt tgttctgccc 150

 tcatctggcc ctggccagct ctgcatttga caaatgccag gaagaggaaa 200

 ctgttgagaa aacggaacta ctggggaaag ggagggctca ctgagaacca 250

 tcccggtaac ccgaccgccg ctggtcacca tgaaccacat tgtgcaaacc 300

 ttctctcctg tcaacagcgg ccagcctccc aactacgaga tgctcaagga 350

 ggagcaggaa gtggctatgc tgggggggcc ccacaaccct gctcccccga 400

 cgtccaccgt gatccacatc cgcagcgaga cctccgtgcc tgaccatgtc 450

 gtctggtccc tgttcaacac cctcttcatg aacacctgct gcctgggctt 500

 catagcattc gcctactccg tgaagtctag ggacaggaag atggttggcg 550

 acgtgaccgg ggcccaggcc tatgcctcca ccgccaagtg cctgaacatc 600

 tgggccctga ttttgggcat cttcatgacc attctgctcg tcatcatccc 650

 agtgttggtc gtccaggccc agcgatagat caggaggcat cattgaggcc 700

 aggagctctg cccgtgacct gtatcccacg tactctatct tccattcctc 750

 gccctgcccc cagaggccag gagctctgcc cttgacctgt attccactta 800

 ctccaccttc cattcctcgc cctgtcccca cagccgagtc ctgcatcagc 850

 cctttatcct cacacgcttt tctacaatgg cattcaataa agtgtatatg 900

 tttct 905

<210> 290
<211> 132
<212> PRT
<213> Homo sapien

<400> 290
 Met Asn His Ile Val Gln Thr Phe Ser Pro Val Asn Ser Gly Gln
   1               5                  10                  15

 Pro Pro Asn Tyr Glu Met Leu Lys Glu Glu Gln Glu Val Ala Met
                  20                  25                  30

 Leu Gly Gly Pro His Asn Pro Ala Pro Pro Thr Ser Thr Val Ile
                  35                  40                  45

 His Ile Arg Ser Glu Thr Ser Val Pro Asp His Val Val Trp Ser
                  50                  55                  60

 Leu Phe Asn Thr Leu Phe Met Asn Thr Cys Cys Leu Gly Phe Ile
                  65                  70                  75

 Ala Phe Ala Tyr Ser Val Lys Ser Arg Asp Arg Lys Met Val Gly
                  80                  85                  90

 Asp Val Thr Gly Ala Gln Ala Tyr Ala Ser Thr Ala Lys Cys Leu
                  95                 100                 105

 Asn Ile Trp Ala Leu Ile Leu Gly Ile Phe Met Thr Ile Leu Leu
                 110                 115                 120

 Val Ile Ile Pro Val Leu Val Val Gln Ala Gln Arg
                 125                 130

<210> 291
<211> 1325
<212> DNA
<213> Homo sapien

<400> 291
 gcgattcggt ggcacgtgga gccacggcgt gggagtaggg ggctgaaggc 50

 aggcagcagc ggccagggcc gccctctgct agccgcttgg gtctcgggat 100

 accccgtttc ttcctgtagg tgtgggacgt gcgtgcggcg agatggacac 150

 tcccccgctc tcggattcgg agtcggaatc cgatgaatcc cttgtcacag 200

 acagagagtt gcaggatgcg ttttcccgag ggcttctgaa gccaggcctc 250

 aatgtcgtgc tagaggggcc gaagaaggcc gtgaacgacg tgaatggcct 300

 gaagcaatgt ttggcagaat tcaagcggga tctggaatgg gttgaaaggc 350

 tcgatgtgac actgggtccg gtaccggaga tcggtggatc tgaggcgcca 400

 gcacctcaga acaaggacca gaaagctgtt gatccagaag acgacttcca 450

 gcgagagatg agtttctatc gccaagccca ggccgcagtg cttgcagtct 500

 taccccgcct ccatcagctc aaagtcccta cgaagcgacc cactgattat 550

 tttgcggaaa tggccaaatc tgatctgcag gtgcagaaga ttcgacagaa 600

 gctgcagact aaacaggctg ccatggagag gtctgaaaaa gctaagcaac 650

 tgcgagcact taggaaatac gggaagaagg tgcaaacgga ggttcttcag 700

 aagaggcagc aggagaaagc ccatatgatg aatgctatta agaaatatca 750

 gaaaggcttc tctgataaac tggatttcct tgagggagat cagaaacctc 800

 tggcacagcg caagaaggca ggagccaaag gccagcagat gaggaagggg 850

 cccagtgcta aacgacggta taaaaaccag aagtttggtt ttggtggaaa 900

 gaagaaaggc tcaaagtgga acactcggga gagctatgat gatgtatcta 950

 gcttccgggc caagacagct catggcagag gcctcaagag gcctggcaag 1000

 aaagggtcaa ataagagacc tggaaaacga acaagagaga agatgaagaa 1050

 cagaacacac taaatagcat ctttgaatac aaagaaccaa gaaaaaggaa 1100

 tgaagactcg caatttcacg acacactttg atcccttctg ttggtgtcat 1150

 gttgtaaaca tttctttcaa taaactaaag aaaaattatt aaaggaacac 1200

 atacctttgg ttaaatagtc tagactaaaa gattgagaag ttactttcca 1250

 ttgctatcta ttgataattt agacattgag ttcaaattgc cttcatttta 1300

 tgataaataa tgatttaact gaaaa 1325

<210> 292
<211> 306
<212> PRT
<213> Homo sapien

<400> 292
 Met Asp Thr Pro Pro Leu Ser Asp Ser Glu Ser Glu Ser Asp Glu
   1               5                  10                  15

 Ser Leu Val Thr Asp Arg Glu Leu Gln Asp Ala Phe Ser Arg Gly
                  20                  25                  30

 Leu Leu Lys Pro Gly Leu Asn Val Val Leu Glu Gly Pro Lys Lys
                  35                  40                  45

 Ala Val Asn Asp Val Asn Gly Leu Lys Gln Cys Leu Ala Glu Phe
                  50                  55                  60

 Lys Arg Asp Leu Glu Trp Val Glu Arg Leu Asp Val Thr Leu Gly
                  65                  70                  75

 Pro Val Pro Glu Ile Gly Gly Ser Glu Ala Pro Ala Pro Gln Asn
                  80                  85                  90

 Lys Asp Gln Lys Ala Val Asp Pro Glu Asp Asp Phe Gln Arg Glu
                  95                 100                 105

 Met Ser Phe Tyr Arg Gln Ala Gln Ala Ala Val Leu Ala Val Leu
                 110                 115                 120

 Pro Arg Leu His Gln Leu Lys Val Pro Thr Lys Arg Pro Thr Asp
                 125                 130                 135

 Tyr Phe Ala Glu Met Ala Lys Ser Asp Leu Gln Val Gln Lys Ile
                 140                 145                 150

 Arg Gln Lys Leu Gln Thr Lys Gln Ala Ala Met Glu Arg Ser Glu
                 155                 160                 165

 Lys Ala Lys Gln Leu Arg Ala Leu Arg Lys Tyr Gly Lys Lys Val
                 170                 175                 180

 Gln Thr Glu Val Leu Gln Lys Arg Gln Gln Glu Lys Ala His Met
                 185                 190                 195

 Met Asn Ala Ile Lys Lys Tyr Gln Lys Gly Phe Ser Asp Lys Leu
                 200                 205                 210

 Asp Phe Leu Glu Gly Asp Gln Lys Pro Leu Ala Gln Arg Lys Lys
                 215                 220                 225

 Ala Gly Ala Lys Gly Gln Gln Met Arg Lys Gly Pro Ser Ala Lys
                 230                 235                 240

 Arg Arg Tyr Lys Asn Gln Lys Phe Gly Phe Gly Gly Lys Lys Lys
                 245                 250                 255

 Gly Ser Lys Trp Asn Thr Arg Glu Ser Tyr Asp Asp Val Ser Ser
                 260                 265                 270

 Phe Arg Ala Lys Thr Ala His Gly Arg Gly Leu Lys Arg Pro Gly
                 275                 280                 285

 Lys Lys Gly Ser Asn Lys Arg Pro Gly Lys Arg Thr Arg Glu Lys
                 290                 295                 300

 Met Lys Asn Arg Thr His
                 305

<210> 293
<211> 2786
<212> DNA
<213> Homo sapien

<400> 293
 agcactctcc agcctctcac cgcaaaatta cacaccccag tacaccagca 50

 gaggaaactt ataacctcgg gaggcgggtc cttcccctca gtgcggtcac 100

 atacttccag aagagcggac cagggctgct gccagcacct gccactcaga 150

 gcgcctctgt cgctgggacc cttcagaact ctctttgctc acaagttacc 200

 aaaaaaaaaa gagccaacat gttggtattg ctggctggta tctttgtggt 250

 ccacatcgct actgttatta tgctatttgt tagcaccatt gccaatgtct 300

 ggttggtttc caatacggta gatgcatcag taggtctttg gaaaaactgt 350

 accaacatta gctgcagtga cagcctgtca tatgccagtg aagatgccct 400

 caagacagtg caggccttca tgattctctc tatcatcttc tgtgtcattg 450

 ccctcctggt cttcgtgttc cagctcttca ccatggagaa gggaaaccgg 500

 ttcttcctct caggggccac cacactggtg tgctggctgt gcattcttgt 550

 gggggtgtcc atctacacta gtcattatgc gaatcgtgat ggaacgcagt 600

 atcaccacgg ctattcctac atcctgggct ggatctgctt ctgcttcagc 650

 ttcatcatcg gcgttctcta tctggtcctg agaaagaaat aaggccggac 700

 gagttcatgg ggatctgggg ggtggggagg aggaagccgt tgaatctggg 750

 agggaagtgg aggttgctgt acaggaaaaa ccgagatagg ggagggggga 800

 gggggaagca aaggggggag gtcaaatccc aaaccattac tgaggggatt 850

 ctctactgcc aagcccctgc cctggggaga aagtagttgg ctagtacttt 900

 gatgctccct tgatggggtc cagagagcct ccctgcagcc accagacttg 950

 gcctccagct gttcttagtg acacacactg tctggggccc catcagctgc 1000

 cacaacacca gccccacttc tgggtcatgc actgaggtcc acagacctac 1050

 tgcactgagt taaaatagcg gtacaagttc tggcaagagc agatactgtc 1100

 tttgtgctga atacgctaag cctggaagcc atcctgccct tctgacccaa 1150

 agcaaaacat cacattccag tctgaagtgc ctactggggg gctttggcct 1200

 gtgagccatt gtccctcttt ggaacagata tttagctctg tggaattcag 1250

 tgacaaaatg ggaggaggaa agagagtttg taaggtcatg ctggtgggtt 1300

 agctaaacca agaaggagac cttttcacaa tggaaaacct gggggatggt 1350

 cagagcccag tcgagacctc acacacggct gtccctcatg gagacctcat 1400

 gccatggtct ttgctaggcc tcttgctgaa agccaaggca gctcttctgg 1450

 agtttctcta aagtcactag tgaacaattc ggtggtaaaa gtaccacaca 1500

 aactatggga tccaaggggc agtcttgcaa cagtgccatg ttagggttat 1550

 gtttttagga ttcccctcaa tgcagtcagt gtttctttta agtatacaac 1600

 aggagagaga tggacatggc tcattgtagc acaatcctat tactcttcct 1650

 ctaacatttt tgaggaagtt ttgtctaatt atcaatattg aggatcaggg 1700

 ctcctaggct cagtggtagc tctggcttag acaccacctg gagtgatcac 1750

 ctcttgggga ccctgcctat cccacttcac aggtgaggca tggcaattct 1800

 ggaagctgat taaaacacac ataaaccaaa accaaacaac aggcccttgg 1850

 gtgaaaggtg ctatataatt gtgaagtatt aagcctaccg tatttcagcc 1900

 atgataagaa cagagtgcct gcattcccag gaaaatacga aaatcccatg 1950

 agataaataa aaatataggt gatgggcaga tcttttcttt aaaataaaaa 2000

 agcaaaaact cttgtggtac ctagtcagat ggtagacgag ctgtctgctg 2050

 ccgcaggagc acctctatac aggacttaga agtagtatgt tattcctggt 2100

 taagcaggca ttgctttgcc ctggagcagc tattttaagc catctcagat 2150

 tctgtctaaa ggggtttttt gggaagacgt tttctttatc gccctgagaa 2200

 gatctacccc agggagaatc tgagacatct tgcctacttt tctttattag 2250

 ctttctcctc atccatttct tttatacctt tcctttttgg ggagttgtta 2300

 tgccatgatt tttggtattt atgtaaaagg attattacta attctatttc 2350

 tctatgttta ttctagttaa ggaaatgttg agggcaagcc accaaattac 2400

 ctaggctgag gttagagaga ttggccagca aaaactgtgg gaagatgaac 2450

 tttgtcatta tgatttcatt atcacatgat tatagaaggc tgtcttagtg 2500

 caaaaaacat acttacattt cagacatatc caaagggaat actcacattt 2550

 tgttaagaag ttgaactatg actggagtaa accatgtatt cccttatctt 2600

 ttactttttt tctgtgacat ttatgtctca tgtaatttgc attactctgg 2650

 tggattgttc tagtactgta ttgggcttct tcgttaatag attatttcat 2700

 atactataat tgtaaatatt ttgatacaaa tgtttataac tctagggata 2750

 taaaaacaga ttctgattcc cttcaaaaaa aaaaaa 2786

<210> 294
<211> 157
<212> PRT
<213> Homo sapien

<400> 294
 Met Leu Val Leu Leu Ala Gly Ile Phe Val Val His Ile Ala Thr
   1               5                  10                  15

 Val Ile Met Leu Phe Val Ser Thr Ile Ala Asn Val Trp Leu Val
                  20                  25                  30

 Ser Asn Thr Val Asp Ala Ser Val Gly Leu Trp Lys Asn Cys Thr
                  35                  40                  45

 Asn Ile Ser Cys Ser Asp Ser Leu Ser Tyr Ala Ser Glu Asp Ala
                  50                  55                  60

 Leu Lys Thr Val Gln Ala Phe Met Ile Leu Ser Ile Ile Phe Cys
                  65                  70                  75

 Val Ile Ala Leu Leu Val Phe Val Phe Gln Leu Phe Thr Met Glu
                  80                  85                  90

 Lys Gly Asn Arg Phe Phe Leu Ser Gly Ala Thr Thr Leu Val Cys
                  95                 100                 105

 Trp Leu Cys Ile Leu Val Gly Val Ser Ile Tyr Thr Ser His Tyr
                 110                 115                 120

 Ala Asn Arg Asp Gly Thr Gln Tyr His His Gly Tyr Ser Tyr Ile
                 125                 130                 135

 Leu Gly Trp Ile Cys Phe Cys Phe Ser Phe Ile Ile Gly Val Leu
                 140                 145                 150

 Tyr Leu Val Leu Arg Lys Lys
                 155

<210> 295
<211> 2786
<212> DNA
<213> Homo sapien

<400> 295
 agcactctcc agcctctcac cgcaaaatta cacaccccag tacaccagca 50

 gaggaaactt ataacctcgg gaggcgggtc cttcccctca gtgcggtcac 100

 atacttccag aagagcggac cagggctgct gccagcacct gccactcaga 150

 gcgcctctgt cgctgggacc cttcagaact ctctttgctc acaagttacc 200

 aaaaaaaaaa gagccaacat gttggtattg ctggctggta tctttgtggt 250

 ccacatcgct actgttatta tgctatttgt tagcaccatt gccaatgtct 300

 ggttggtttc caatacggta gatgcatcag taggtctttg gaaaaactgt 350

 accaacatta gctgcagtga cagcctgtca tatgccagtg aagatgccct 400

 caagacagtg caggccttca tgattctctc tatcatcttc tgtgtcattg 450

 ccctcctggt cttcgtgttc cagctcttca ccatggagaa gggaaaccgg 500

 ttcttcctct caggggccac cacactggtg tgctggctgt gcattcttgt 550

 gggggtgtcc atctacacta gtcattatgc gaatcgtgat ggaacgcagt 600

 atcaccacgg ctattcctac atcctgggct ggatctgctt ctgcttcagc 650

 ttcatcatcg gcgttctcta tctggtcctg agaaagaaat aaggccggac 700

 gagttcatgg ggatctgggg ggtggggagg aggaagccgt tgaatctggg 750

 agggaagtgg aggttgctgt acaggaaaaa ccgagatagg ggagggggga 800

 gggggaagca aaggggggag gtcaaatccc aaaccattac tgaggggatt 850

 ctctactgcc aagcccctgc cctggggaga aagtagttgg ctagtacttt 900

 gatgctccct tgatggggtc cagagagcct ccctgcagcc accagacttg 950

 gcctccagct gttcttagtg acacacactg tctggggccc catcagctgc 1000

 cacaacacca gccccacttc tgggtcatgc actgaggtcc acagacctac 1050

 tgcactgagt taaaatagcg gtacaagttc tggcaagagc agatactgtc 1100

 tttgtgctga atacgctaag cctggaagcc atcctgccct tctgacccaa 1150

 agcaaaacat cacattccag tctgaagtgc ctactggggg gctttggcct 1200

 gtgagccatt gtccctcttt ggaacagata tttagctctg tggaattcag 1250

 tgacaaaatg ggaggaggaa agagagtttg taaggtcatg ctggtgggtt 1300

 agctaaacca agaaggagac cttttcacaa tggaaaacct gggggatggt 1350

 cagagcccag tcgagacctc acacacggct gtccctcatg gagacctcat 1400

 gccatggtct ttgctaggcc tcttgctgaa agccaaggca gctcttctgg 1450

 agtttctcta aagtcactag tgaacaattc ggtggtaaaa gtaccacaca 1500

 aactatggga tccaaggggc agtcttgcaa cagtgccatg ttagggttat 1550

 gtttttagga ttcccctcaa tgcagtcagt gtttctttta agtatacaac 1600

 aggagagaga tggacatggc tcattgtagc acaatcctat tactcttcct 1650

 ctaacatttt tgaggaagtt ttgtctaatt atcaatattg aggatcaggg 1700

 ctcctaggct cagtggtagc tctggcttag acaccacctg gagtgatcac 1750

 ctcttgggga ccctgcctat cccacttcac aggtgaggca tggcaattct 1800

 ggaagctgat taaaacacac ataaaccaaa accaaacaac aggcccttgg 1850

 gtgaaaggtg ctatataatt gtgaagtatt aagcctaccg tatttcagcc 1900

 atgataagaa cagagtgcct gcattcccag gaaaatacga aaatcccatg 1950

 agataaataa aaatataggt gatgggcaga tcttttcttt aaaataaaaa 2000

 agcaaaaact cttgtggtac ctagtcagat ggtagacgag ctgtctgctg 2050

 ccgcaggagc acctctatac aggacttaga agtagtatgt tattcctggt 2100

 taagcaggca ttgctttgcc ctggagcagc tattttaagc catctcagat 2150

 tctgtctaaa ggggtttttt gggaagacgt tttctttatc gccctgagaa 2200

 gatctacccc agggagaatc tgagacatct tgcctacttt tctttattag 2250

 ctttctcctc atccatttct tttatacctt tcctttttgg ggagttgtta 2300

 tgccatgatt tttggtattt atgtaaaagg attattacta attctatttc 2350

 tctatgttta ttctagttaa ggaaatgttg agggcaagcc accaaattac 2400

 ctaggctgag gttagagaga ttggccagca aaaactgtgg gaagatgaac 2450

 tttgtcatta tgatttcatt atcacatgat tatagaaggc tgtcttagtg 2500

 caaaaaacat acttacattt cagacatatc caaagggaat actcacattt 2550

 tgttaagaag ttgaactatg actggagtaa accatgtatt cccttatctt 2600

 ttactttttt tctgtgacat ttatgtctca tgtaatttgc attactctgg 2650

 tggattgttc tagtactgta ttgggcttct tcgttaatag attatttcat 2700

 atactataat tgtaaatatt ttgatacaaa tgtttataac tctagggata 2750

 taaaaacaga ttctgattcc cttcaaaaaa aaaaaa 2786

<210> 296
<211> 157
<212> PRT
<213> Homo sapien

<400> 296
 Met Leu Val Leu Leu Ala Gly Ile Phe Val Val His Ile Ala Thr
   1               5                  10                  15

 Val Ile Met Leu Phe Val Ser Thr Ile Ala Asn Val Trp Leu Val
                  20                  25                  30

 Ser Asn Thr Val Asp Ala Ser Val Gly Leu Trp Lys Asn Cys Thr
                  35                  40                  45

 Asn Ile Ser Cys Ser Asp Ser Leu Ser Tyr Ala Ser Glu Asp Ala
                  50                  55                  60

 Leu Lys Thr Val Gln Ala Phe Met Ile Leu Ser Ile Ile Phe Cys
                  65                  70                  75

 Val Ile Ala Leu Leu Val Phe Val Phe Gln Leu Phe Thr Met Glu
                  80                  85                  90

 Lys Gly Asn Arg Phe Phe Leu Ser Gly Ala Thr Thr Leu Val Cys
                  95                 100                 105

 Trp Leu Cys Ile Leu Val Gly Val Ser Ile Tyr Thr Ser His Tyr
                 110                 115                 120

 Ala Asn Arg Asp Gly Thr Gln Tyr His His Gly Tyr Ser Tyr Ile
                 125                 130                 135

 Leu Gly Trp Ile Cys Phe Cys Phe Ser Phe Ile Ile Gly Val Leu
                 140                 145                 150

 Tyr Leu Val Leu Arg Lys Lys
                 155

<210> 297
<211> 2562
<212> DNA
<213> Homo sapien

<400> 297
 gccgcgccgg ctctgggcac tcagcatcgt ttccttttcc tccgctggag 50

 cagctatggc ggcggtgaag accctgaacc ccaaggccga ggtggcccga 100

 gcgcaggcgg cgctggcggt caacatcagc gcagcgcggg gtctgcagga 150

 cgtgctaagg accaacctgg ggcccaaggg caccatgaag atgctcgttt 200

 ctggcgctgg agacatcaaa cttactaaag acggcaatgt gctgcttcac 250

 gaaatgcaaa ttcaacaccc aacagcttcc ttaatagcaa aggtagcaac 300

 agcccaggat gatataactg gtgatggtac gacttctaat gtcctaatca 350

 ttggagagct gctgaaacag gcggatctct acatttctga aggccttcat 400

 cctagaataa tcactgaagg atttgaagct gcaaaggaaa aggcccttca 450

 gtttttggaa gaagtcaaag taagcagaga gatggacagg gaaacactta 500

 tagatgtggc cagaacatct cttcgtacta aagttcatgc tgaacttgca 550

 gatgtcttaa cagaggctgt agtggactcc attttggcca ttaaaaagca 600

 agatgaacct attgatctct tcatgattga gatcatggag atgaaacata 650

 aatctgaaac tgatacaagc ttaatcagag ggcttgtttt ggaccacgga 700

 gcacggcatc ctgatatgaa gaaaagggtg gaggatgcat acatcctcac 750

 ttgtaacgtg tcattagagt atgagaaaac agaagtgaat tctggctttt 800

 tttacaagag tgcagaagag agagaaaaac tcgtgaaagc tgaaagaaaa 850

 ttcattgaag atagggttaa aaaaataata gaactgaaaa ggaaagtctg 900

 tggcgattca gataaaggat ttgttgttat taatcaaaag ggaattgacc 950

 ccttttcctt agatgctctt tcaaaagaag gcatagtcgc tctgcgcaga 1000

 gctaaaagga gaaatatgga gaggctgact cttgcttgtg gtggggtagc 1050

 cctgaattct tttgacgacc taagtcctga ctgcttggga catgcaggac 1100

 ttgtatatga gtatacattg ggagaagaga agtttacctt tattgagaaa 1150

 tgtaacaacc ctcgttctgt cacattattg atcaaaggac caaataagca 1200

 cacactcact cagatcaaag atgcagtgag ggacggcttg agggctgtca 1250

 aaaatgctat tgatgatggc tgtgtggttc caggtgctgg tgccgtggaa 1300

 gtggcaatgg cagaagccct gattaaacat aagcccagtg taaagggcag 1350

 ggcacagctt ggagtccaag catttgctga tgcattgctc attattccca 1400

 aggttcttgc tcagaactct ggttttgacc ttcaggaaac attagttaaa 1450

 attcaagcag aacattcaga atcaggtcag cttgtgggtg tggacctgaa 1500

 cacaggtgag ccaatggtgg cagcagaagt aggcgtatgg gataactatt 1550

 gtgtaaagaa acagcttctt cactcctgca ctgtgattgc caccaacatt 1600

 ctcttggttg atgagatcat gcgagctgga atgtcttctc tgaaaggttg 1650

 aattgaagct tcctctgtat ctgaatcttg aagactgcaa agtgatcctg 1700

 aggattacag ctgtggaatt tttgtccaag cttcaaataa ttttgaaaga 1750

 aattttccca tatgaaaaaa ggagagaaca ctggcatctg ttgaaatttg 1800

 gaagttctga aattatagta tttttaaaaa ttgcactgaa gtgtatacac 1850

 ataaagcagg tcttttatcc agtgaacagg atgttttgct ttagcagcag 1900

 tgacataaaa ttccatgtta gataagcata tgttacttac cttgttatta 1950

 aatatttctt gaaaagcaaa ttttaatggt taattttatg tggacgtatg 2000

 ttaaattatc caaactaccc tattgttaag catttggttt taaaattttt 2050

 atgctaatat aaatgctcaa gtaatttaaa atattgaaag catccctgtt 2100

 ggtataaatt tctgagtaaa tgcattggat cagttggact ttgaacgccc 2150

 tttgaaatgg ctttgctaaa atgctcccgc cacaaagttg taggaaatgg 2200

 gaagaggagt caactagagg caagggagtt gagagagctg caactgtaaa 2250

 gggcaagaac aggcagaggt aaaaagatga tggaaggtgt ggtgactaag 2300

 ggccacggtt attgggtgaa atttgagatg taggccaact gtattttcaa 2350

 gcttctgaac ttaaggcaaa atattcatcg caaagtctct agcgtcatat 2400

 ttttctcacc caaattacgt ttccacgagt tattatatat agttggtcta 2450

 tctctgcagt ccttgaaggt gaagttgtgt gttactaggc tgtgttttgg 2500

 gatgtcagca gtggcctgaa gtgagttgtg caataaatgt taagttgaaa 2550

 cctcaaaaaa aa 2562

<210> 298
<211> 531
<212> PRT
<213> Homo sapien

<400> 298
 Met Ala Ala Val Lys Thr Leu Asn Pro Lys Ala Glu Val Ala Arg
   1               5                  10                  15

 Ala Gln Ala Ala Leu Ala Val Asn Ile Ser Ala Ala Arg Gly Leu
                  20                  25                  30

 Gln Asp Val Leu Arg Thr Asn Leu Gly Pro Lys Gly Thr Met Lys
                  35                  40                  45

 Met Leu Val Ser Gly Ala Gly Asp Ile Lys Leu Thr Lys Asp Gly
                  50                  55                  60

 Asn Val Leu Leu His Glu Met Gln Ile Gln His Pro Thr Ala Ser
                  65                  70                  75

 Leu Ile Ala Lys Val Ala Thr Ala Gln Asp Asp Ile Thr Gly Asp
                  80                  85                  90

 Gly Thr Thr Ser Asn Val Leu Ile Ile Gly Glu Leu Leu Lys Gln
                  95                 100                 105

 Ala Asp Leu Tyr Ile Ser Glu Gly Leu His Pro Arg Ile Ile Thr
                 110                 115                 120

 Glu Gly Phe Glu Ala Ala Lys Glu Lys Ala Leu Gln Phe Leu Glu
                 125                 130                 135

 Glu Val Lys Val Ser Arg Glu Met Asp Arg Glu Thr Leu Ile Asp
                 140                 145                 150

 Val Ala Arg Thr Ser Leu Arg Thr Lys Val His Ala Glu Leu Ala
                 155                 160                 165

 Asp Val Leu Thr Glu Ala Val Val Asp Ser Ile Leu Ala Ile Lys
                 170                 175                 180

 Lys Gln Asp Glu Pro Ile Asp Leu Phe Met Ile Glu Ile Met Glu
                 185                 190                 195

 Met Lys His Lys Ser Glu Thr Asp Thr Ser Leu Ile Arg Gly Leu
                 200                 205                 210

 Val Leu Asp His Gly Ala Arg His Pro Asp Met Lys Lys Arg Val
                 215                 220                 225

 Glu Asp Ala Tyr Ile Leu Thr Cys Asn Val Ser Leu Glu Tyr Glu
                 230                 235                 240

 Lys Thr Glu Val Asn Ser Gly Phe Phe Tyr Lys Ser Ala Glu Glu
                 245                 250                 255

 Arg Glu Lys Leu Val Lys Ala Glu Arg Lys Phe Ile Glu Asp Arg
                 260                 265                 270

 Val Lys Lys Ile Ile Glu Leu Lys Arg Lys Val Cys Gly Asp Ser
                 275                 280                 285

 Asp Lys Gly Phe Val Val Ile Asn Gln Lys Gly Ile Asp Pro Phe
                 290                 295                 300

 Ser Leu Asp Ala Leu Ser Lys Glu Gly Ile Val Ala Leu Arg Arg
                 305                 310                 315

 Ala Lys Arg Arg Asn Met Glu Arg Leu Thr Leu Ala Cys Gly Gly
                 320                 325                 330

 Val Ala Leu Asn Ser Phe Asp Asp Leu Ser Pro Asp Cys Leu Gly
                 335                 340                 345

 His Ala Gly Leu Val Tyr Glu Tyr Thr Leu Gly Glu Glu Lys Phe
                 350                 355                 360

 Thr Phe Ile Glu Lys Cys Asn Asn Pro Arg Ser Val Thr Leu Leu
                 365                 370                 375

 Ile Lys Gly Pro Asn Lys His Thr Leu Thr Gln Ile Lys Asp Ala
                 380                 385                 390

 Val Arg Asp Gly Leu Arg Ala Val Lys Asn Ala Ile Asp Asp Gly
                 395                 400                 405

 Cys Val Val Pro Gly Ala Gly Ala Val Glu Val Ala Met Ala Glu
                 410                 415                 420

 Ala Leu Ile Lys His Lys Pro Ser Val Lys Gly Arg Ala Gln Leu
                 425                 430                 435

 Gly Val Gln Ala Phe Ala Asp Ala Leu Leu Ile Ile Pro Lys Val
                 440                 445                 450

 Leu Ala Gln Asn Ser Gly Phe Asp Leu Gln Glu Thr Leu Val Lys
                 455                 460                 465

 Ile Gln Ala Glu His Ser Glu Ser Gly Gln Leu Val Gly Val Asp
                 470                 475                 480

 Leu Asn Thr Gly Glu Pro Met Val Ala Ala Glu Val Gly Val Trp
                 485                 490                 495

 Asp Asn Tyr Cys Val Lys Lys Gln Leu Leu His Ser Cys Thr Val
                 500                 505                 510

 Ile Ala Thr Asn Ile Leu Leu Val Asp Glu Ile Met Arg Ala Gly
                 515                 520                 525

 Met Ser Ser Leu Lys Gly
                 530

<210> 299
<211> 2562
<212> DNA
<213> Homo sapien

<400> 299
 gccgcgccgg ctctgggcac tcagcatcgt ttccttttcc tccgctggag 50

 cagctatggc ggcggtgaag accctgaacc ccaaggccga ggtggcccga 100

 gcgcaggcgg cgctggcggt caacatcagc gcagcgcggg gtctgcagga 150

 cgtgctaagg accaacctgg ggcccaaggg caccatgaag atgctcgttt 200

 ctggcgctgg agacatcaaa cttactaaag acggcaatgt gctgcttcac 250

 gaaatgcaaa ttcaacaccc aacagcttcc ttaatagcaa aggtagcaac 300

 agcccaggat gatataactg gtgatggtac gacttctaat gtcctaatca 350

 ttggagagct gctgaaacag gcggatctct acatttctga aggccttcat 400

 cctagaataa tcactgaagg atttgaagct gcaaaggaaa aggcccttca 450

 gtttttggaa gaagtcaaag taagcagaga gatggacagg gaaacactta 500

 tagatgtggc cagaacatct cttcgtacta aagttcatgc tgaacttgca 550

 gatgtcttaa cagaggctgt agtggactcc attttggcca ttaaaaagca 600

 agatgaacct attgatctct tcatgattga gatcatggag atgaaacata 650

 aatctgaaac tgatacaagc ttaatcagag ggcttgtttt ggaccacgga 700

 gcacggcatc ctgatatgaa gaaaagggtg gaggatgcat acatcctcac 750

 ttgtaacgtg tcattagagt atgagaaaac agaagtgaat tctggctttt 800

 tttacaagag tgcagaagag agagaaaaac tcgtgaaagc tgaaagaaaa 850

 ttcattgaag atagggttaa aaaaataata gaactgaaaa ggaaagtctg 900

 tggcgattca gataaaggat ttgttgttat taatcaaaag ggaattgacc 950

 ccttttcctt agatgctctt tcaaaagaag gcatagtcgc tctgcgcaga 1000

 gctaaaagga gaaatatgga gaggctgact cttgcttgtg gtggggtagc 1050

 cctgaattct tttgacgacc taagtcctga ctgcttggga catgcaggac 1100

 ttgtatatga gtatacattg ggagaagaga agtttacctt tattgagaaa 1150

 tgtaacaacc ctcgttctgt cacattattg atcaaaggac caaataagca 1200

 cacactcact cagatcaaag atgcagtgag ggacggcttg agggctgtca 1250

 aaaatgctat tgatgatggc tgtgtggttc caggtgctgg tgccgtggaa 1300

 gtggcaatgg cagaagccct gattaaacat aagcccagtg taaagggcag 1350

 ggcacagctt ggagtccaag catttgctga tgcattgctc attattccca 1400

 aggttcttgc tcagaactct ggttttgacc ttcaggaaac attagttaaa 1450

 attcaagcag aacattcaga atcaggtcag cttgtgggtg tggacctgaa 1500

 cacaggtgag ccaatggtgg cagcagaagt aggcgtatgg gataactatt 1550

 gtgtaaagaa acagcttctt cactcctgca ctgtgattgc caccaacatt 1600

 ctcttggttg atgagatcat gcgagctgga atgtcttctc tgaaaggttg 1650

 aattgaagct tcctctgtat ctgaatcttg aagactgcaa agtgatcctg 1700

 aggattacag ctgtggaatt tttgtccaag cttcaaataa ttttgaaaga 1750

 aattttccca tatgaaaaaa ggagagaaca ctggcatctg ttgaaatttg 1800

 gaagttctga aattatagta tttttaaaaa ttgcactgaa gtgtatacac 1850

 ataaagcagg tcttttatcc agtgaacagg atgttttgct ttagcagcag 1900

 tgacataaaa ttccatgtta gataagcata tgttacttac cttgttatta 1950

 aatatttctt gaaaagcaaa ttttaatggt taattttatg tggacgtatg 2000

 ttaaattatc caaactaccc tattgttaag catttggttt taaaattttt 2050

 atgctaatat aaatgctcaa gtaatttaaa atattgaaag catccctgtt 2100

 ggtataaatt tctgagtaaa tgcattggat cagttggact ttgaacgccc 2150

 tttgaaatgg ctttgctaaa atgctcccgc cacaaagttg taggaaatgg 2200

 gaagaggagt caactagagg caagggagtt gagagagctg caactgtaaa 2250

 gggcaagaac aggcagaggt aaaaagatga tggaaggtgt ggtgactaag 2300

 ggccacggtt attgggtgaa atttgagatg taggccaact gtattttcaa 2350

 gcttctgaac ttaaggcaaa atattcatcg caaagtctct agcgtcatat 2400

 ttttctcacc caaattacgt ttccacgagt tattatatat agttggtcta 2450

 tctctgcagt ccttgaaggt gaagttgtgt gttactaggc tgtgttttgg 2500

 gatgtcagca gtggcctgaa gtgagttgtg caataaatgt taagttgaaa 2550

 cctcaaaaaa aa 2562

<210> 300
<211> 531
<212> PRT
<213> Homo sapien

<400> 300
 Met Ala Ala Val Lys Thr Leu Asn Pro Lys Ala Glu Val Ala Arg
   1               5                  10                  15

 Ala Gln Ala Ala Leu Ala Val Asn Ile Ser Ala Ala Arg Gly Leu
                  20                  25                  30

 Gln Asp Val Leu Arg Thr Asn Leu Gly Pro Lys Gly Thr Met Lys
                  35                  40                  45

 Met Leu Val Ser Gly Ala Gly Asp Ile Lys Leu Thr Lys Asp Gly
                  50                  55                  60

 Asn Val Leu Leu His Glu Met Gln Ile Gln His Pro Thr Ala Ser
                  65                  70                  75

 Leu Ile Ala Lys Val Ala Thr Ala Gln Asp Asp Ile Thr Gly Asp
                  80                  85                  90

 Gly Thr Thr Ser Asn Val Leu Ile Ile Gly Glu Leu Leu Lys Gln
                  95                 100                 105

 Ala Asp Leu Tyr Ile Ser Glu Gly Leu His Pro Arg Ile Ile Thr
                 110                 115                 120

 Glu Gly Phe Glu Ala Ala Lys Glu Lys Ala Leu Gln Phe Leu Glu
                 125                 130                 135

 Glu Val Lys Val Ser Arg Glu Met Asp Arg Glu Thr Leu Ile Asp
                 140                 145                 150

 Val Ala Arg Thr Ser Leu Arg Thr Lys Val His Ala Glu Leu Ala
                 155                 160                 165

 Asp Val Leu Thr Glu Ala Val Val Asp Ser Ile Leu Ala Ile Lys
                 170                 175                 180

 Lys Gln Asp Glu Pro Ile Asp Leu Phe Met Ile Glu Ile Met Glu
                 185                 190                 195

 Met Lys His Lys Ser Glu Thr Asp Thr Ser Leu Ile Arg Gly Leu
                 200                 205                 210

 Val Leu Asp His Gly Ala Arg His Pro Asp Met Lys Lys Arg Val
                 215                 220                 225

 Glu Asp Ala Tyr Ile Leu Thr Cys Asn Val Ser Leu Glu Tyr Glu
                 230                 235                 240

 Lys Thr Glu Val Asn Ser Gly Phe Phe Tyr Lys Ser Ala Glu Glu
                 245                 250                 255

 Arg Glu Lys Leu Val Lys Ala Glu Arg Lys Phe Ile Glu Asp Arg
                 260                 265                 270

 Val Lys Lys Ile Ile Glu Leu Lys Arg Lys Val Cys Gly Asp Ser
                 275                 280                 285

 Asp Lys Gly Phe Val Val Ile Asn Gln Lys Gly Ile Asp Pro Phe
                 290                 295                 300

 Ser Leu Asp Ala Leu Ser Lys Glu Gly Ile Val Ala Leu Arg Arg
                 305                 310                 315

 Ala Lys Arg Arg Asn Met Glu Arg Leu Thr Leu Ala Cys Gly Gly
                 320                 325                 330

 Val Ala Leu Asn Ser Phe Asp Asp Leu Ser Pro Asp Cys Leu Gly
                 335                 340                 345

 His Ala Gly Leu Val Tyr Glu Tyr Thr Leu Gly Glu Glu Lys Phe
                 350                 355                 360

 Thr Phe Ile Glu Lys Cys Asn Asn Pro Arg Ser Val Thr Leu Leu
                 365                 370                 375

 Ile Lys Gly Pro Asn Lys His Thr Leu Thr Gln Ile Lys Asp Ala
                 380                 385                 390

 Val Arg Asp Gly Leu Arg Ala Val Lys Asn Ala Ile Asp Asp Gly
                 395                 400                 405

 Cys Val Val Pro Gly Ala Gly Ala Val Glu Val Ala Met Ala Glu
                 410                 415                 420

 Ala Leu Ile Lys His Lys Pro Ser Val Lys Gly Arg Ala Gln Leu
                 425                 430                 435

 Gly Val Gln Ala Phe Ala Asp Ala Leu Leu Ile Ile Pro Lys Val
                 440                 445                 450

 Leu Ala Gln Asn Ser Gly Phe Asp Leu Gln Glu Thr Leu Val Lys
                 455                 460                 465

 Ile Gln Ala Glu His Ser Glu Ser Gly Gln Leu Val Gly Val Asp
                 470                 475                 480

 Leu Asn Thr Gly Glu Pro Met Val Ala Ala Glu Val Gly Val Trp
                 485                 490                 495

 Asp Asn Tyr Cys Val Lys Lys Gln Leu Leu His Ser Cys Thr Val
                 500                 505                 510

 Ile Ala Thr Asn Ile Leu Leu Val Asp Glu Ile Met Arg Ala Gly
                 515                 520                 525

 Met Ser Ser Leu Lys Gly
                 530

<210> 301
<211> 9501
<212> DNA
<213> Homo sapien

<400> 301
 ggccccaatg agtggcacac agtctactat caccgacagg tttcccctca 50

 aaaaacctat aaggcatgga agtattttga accgagagtc accaacagat 100

 aagaagcaga aagttgagcg cattgcatca catgattttg accccacaga 150

 tagctcctcc aagaagacaa agtctagttc agaggagagt agatccgaga 200

 tatatggtct tgttcagcgt tgcgtaatca tccagaaaga tgacaatgga 250

 tttgggctga cggtcagtgg agacaatcca gtcttcgtac agtctgtcaa 300

 agaagatgga gcagccatgc gggctggagt acagacaggt gatcgaatca 350

 tcaaggtgaa tggaactctg gtgactcatt caaatcatct ggaggtggtg 400

 aagctaatca aatctggttc ctatgtagct ctcactgttc agggacgccc 450

 acctgggtcg ccccagattc cacttgccga ctctgaagta gagccgtcag 500

 tcattggaca tatgtctccc atcatgacat ctcctcattc acctggagca 550

 tctgggaata tggagagaat cactagtcct gtgctcatgg gggaggaaaa 600

 caatgtggtt cataaccaga aagtagaaat tctgagaaaa atgttacaga 650

 aagaacagga acggctacag ttattgcagg aagattacaa ccgaacacct 700

 gcccaaagat tgctaaaaga gatccaagag gccaagaaac acattcctca 750

 gctgcaagag cagttatcca aagccacagg ctctgctcag gatggagctg 800

 tagttacacc ctccagacct ttaggggaca ccctaacagt cagtgaggca 850

 gaaacagatc ctggagatgt actgggcagg actgactgta gcagtggaga 900

 tgcttctcgg cccagtagtg acaatgcaga tagtcccaag agtggcccaa 950

 aagagagaat ttatctagag gaaaacccag agaaaagtga aacaattcag 1000

 gacactgaca ctcaatcact tgtcggaagt ccctcaaccc gtatagcacc 1050

 tcatattatt ggagcagaag atgatgattt tggtactgaa catgaacaga 1100

 tcaatggaca gtgcagctgt ttccagagca ttgaattact aaaatctcgc 1150

 ccggctcatt tggctgtttt cttacaccat gtagtttcac aatttgaccc 1200

 tgcgactttg ctctgttatc tctattcaga cctgtataaa cataccaatt 1250

 ccaaagaaac tcgtcgcatc ttccttgagt ttcatcagtt ctttctagat 1300

 cgatcagcac acctgaaagt ttctgttcct gatgaaatgt ctgcagatct 1350

 agaaaagaga agacctgagc tcattcctga ggatctgcat cgccactata 1400

 tccaaactat gcaagaaaga gtccatccag aagttcaaag gcacttagaa 1450

 gattttcggc agaaacgtag tatgggactg accttggctg aaagcgagct 1500

 gactaaactt gatgcagagc gagacaagga ccgattgact ttggagaagg 1550

 agcggacatg tgcagaacag attgttgcca aaattgaaga agtattgatg 1600

 actgctcagg ctgtagagga agataagagc tccaccatgc agtatgttat 1650

 tctcatgtat atgaagcatt tgggagtaaa agtgaaagag cctcgaaatt 1700

 tggagcacaa acggggtcgg attggatttc ttcccaaaat caagcaaagt 1750

 atgaagaaag ataaagaagg ggaagaaaaa gggaagcgaa gaggattccc 1800

 cagcatcctg ggacccccac ggagaccaag ccgtcatgac aacagtgcaa 1850

 ttggcagagc catggaacta cagaaggcgc gccaccctaa gcacttatcc 1900

 acaccctcat ctgtgagtcc tgaacctcag gactctgcca agttgcgcca 1950

 gagtgggtta gcaaatgaag gaacagacgc tggatacctg cctgccaatt 2000

 ccatgtcttc tgtagcttca ggggcctctt tttcccagga aggagggaaa 2050

 gagaatgata caggatcaaa gcaagttgga gaaacatcag cacctggaga 2100

 caccttagat ggcacacctc gtactctcaa tactgtcttt gatttcccac 2150

 cacctccatt agaccaagtg caggaggagg aatgtgaagt agaaagggtg 2200

 actgaacatg ggacaccaaa gccctttcga aagtttgaca gtgtagcttt 2250

 tggagaaagt caaagtgagg atgaacaatt tgaaaatgac ttagagacag 2300

 acccacccaa ctggcagcag cttgttagtc gagaagtgtt actgggacta 2350

 aaaccttgtg aaatcaaaag acaggaagtg attaatgaat tgttctacac 2400

 tgaaagagct catgttcgaa cactgaaggt tcttgatcaa gtgttctatc 2450

 agcgagtatc cagagaagga attctgtcac cctcagagct acggaaaatt 2500

 ttttcaaact tggaagatat tcttcaactt catattggat tgaatgaaca 2550

 aatgaaggct gttcgaaaga gaaatgagac ctctgttatc gatcagattg 2600

 gggaagattt gctgacatgg ttcagcggac caggagagga gaaattgaaa 2650

 catgctgctg ctaccttttg cagtaaccaa cctttcgccc tggaaatgat 2700

 caaatctcgt cagaaaaagg attctcgatt tcagactttt gtgcaagatg 2750

 ctgaaagtaa tccactgtgt cgtcgtcttc aactgaagga tattattccc 2800

 actcaaatgc aaaggcttac taagtaccca cttctgttgg ataatattgc 2850

 caaatacaca gaatggccaa cagaaaggga gaaggtgaag aaagctgcag 2900

 atcactgtcg tcagatctta aattatgtaa atcaggctgt caaggaggca 2950

 gaaaacaagc agcgcctaga agattatcag cgtcgccttg atacctccag 3000

 cctgaagttg tcagagtacc caaatgttga agagctcagg aatttggatt 3050

 taacaaaaag gaagatgatt catgaagggc cattggtttg gaaggtgaat 3100

 agagataaaa ctattgattt atacacgttg ctgctggaag acattcttgt 3150

 attgttacaa aagcaggatg atagactggt tttaaggtgt catagtaaga 3200

 ttctggcatc tacagctgat agcaaacaca cgtttagccc tgtcattaag 3250

 ttgagtacag tgttggttcg acaagtggca acagataaca aagctttatt 3300

 cgtcatttcc atgtcagaca atggcgctca gatttatgaa ctggtggcac 3350

 agacagtttc tgaaaagact gtctggcagg acctaatctg tcggatggct 3400

 gcatcagtga aggagcaatc cacaaagcca attccattac cacagtcaac 3450

 acctggcgaa ggagataatg atgaagaaga tccttcaaaa ttaaaagagg 3500

 agcagcatgg catttcagtc actggtttgc agagtccaga cagagatttg 3550

 ggattagaat ctaccttaat atcgtcaaaa cctcagtctc attcactgag 3600

 tacctctggg aaatcagagg tacgtgatct gtttgtggct gagagacagt 3650

 ttgcaaagga acaacataca gatgggacac taaaggaagt tggagaagat 3700

 tatcaaatcg caatcccaga ttcacacctg cctgtctcag aagaacggtg 3750

 ggcattggat gcactaagaa atttgggttt gttgaagcag ttgctggtgc 3800

 aacagctagg tttgactgag aagagcgttc aggaagactg gcaacatttc 3850

 ccaagataca gaacagcctc tcaggggccg cagacagaca gtgtcatcca 3900

 gaactctgaa aatattaagg cctatcattc tggtgaagga catatgccct 3950

 ttagaactgg aactggtgac attgcaactt gttacagtcc acggacttca 4000

 actgaatctt ttgctccacg ggattcagtg ggactggcac cccaggatag 4050

 ccaggcaagt aacattttag taatggacca catgattatg accccagaga 4100

 tgcctaccat ggagccagaa gggggtcttg atgacagtgg agagcacttt 4150

 tttgatgccc gtgaagcaca tagtgatgag aatccatcag aaggtgatgg 4200

 agcagttaac aaggaagaga aggatgttaa tttacgcatc tcaggaaact 4250

 atttgatcct tgatggctat gacccagtgc aggagagttc cacagatgag 4300

 gaggttgctt cctcacttac cctgcagccc atgacaggca tccctgctgt 4350

 ggaatccacc caccagcagc aacattctcc tcagaatact cactccgatg 4400

 gggcaatttc accattcacc cccgaatttc tggtccagca gcgctgggga 4450

 gctatggagt attcctgttt tgagatccag agtccctcct cttgtgcaga 4500

 ttcacagagc cagatcatgg agtacattca taagatagag gctgaccttg 4550

 aacacttaaa gaaggtggag gaaagttaca ccattctttg ccaaaggctg 4600

 gctggatcag ccctcacaga caagcactca gataaaagtt agagccgcat 4650

 gtcctggagg tgactgcagg ttgttggatt tggagtatcg gccgtgtctc 4700

 accacatcct ggctccagtg tggatgcaga gagagtgtga cagaggatct 4750

 gcctgtgaac cacctgggat tagtcaagtc ccaaggtgcc cagagtggga 4800

 ctagttcttc acagtgtggc agctgcacta atctgtttgt gagggaatat 4850

 ccattccctc actctactct cctcactatc ggaaattcat tttgattcag 4900

 aataaaaacc aaatgtatag agctttgggt gtaggatatg aaattgtact 4950

 tagatttaag aaaaagagaa aatcagatgt atttatttga cttcattccg 5000

 tatttgaaag cacattttaa tttttatttg ccttgttttg ttttaattga 5050

 gtagtgagag ttttagacct ttgtctttag tacacccaag gatcaactgc 5100

 tcctgaagca aagaggtcag gatggagtat gcagaagttg ggtagagagg 5150

 ttaagaagag gaggaagtga gacggggaag ggaggagcac cttgcttcac 5200

 tatacagtat tccaagctct ctgctgtcca gtaggctgct tctctgaggg 5250

 tcacctcaaa ggtatgctat gccgtgtggc tcttatgtgc ccaggtggtg 5300

 tggtcagaga gtggatgggc ttcctcccgc cctgaggcaa gcacctcttc 5350

 tctgtagctg ggatcaacca caattaatag gaatcctcaa catactaaat 5400

 agcaggcact tgaaaatggg tgtgttttct tccattgtcg tcttttctat 5450

 tgagggttgg gatttgggtg ggagaggaaa gcaaatttta ttttcttgac 5500

 tataaatttg ttattcttgg tatcatttca tttttataat tatacattag 5550

 acattggcac ttgtgtaaaa ctgtccctgc agattgagca ggaagtaaaa 5600

 acaaatggaa atgcttcgga tagtggcagg ggtgggggtt gctaaggaaa 5650

 gggtgggatg ggagtgggta aagagtttgg gaaggttatc taactgaatc 5700

 actactgagt tgaatcatgg ctatcattag ccacaggtac tgctgattat 5750

 aaggccagta aaattttagt acctggaggt ttgactctaa tttttgcact 5800

 gatggtgcca aagggccctg agtcaaaagg atagccaagg gtggagtgga 5850

 aaaagatatg gtgaaggcag aactgctcac accagctcca gaagcacgtc 5900

 ctctgacttc actgccgcag ctctttccac acggggccgt gattgaccct 5950

 aaaaattgca gaccagcaca tacactggac actgcaggca aggtgttggt 6000

 aactgcctgc tctaggatga atagtagcgt tagcagcacc ctacagaggg 6050

 taagtttcag aattgtaatt tgagaactcc ttcaattata ttgactttct 6100

 ttggttttcc ttgtgcatta ggtatatatt ttttgaagta tttttgccaa 6150

 ctaaaatgaa gtctgtaaat tctgttaata aacaaggagt tcatccgttg 6200

 ctcacatctt tcattggtgc cctctgaact ctgtgggttg ctaggatgta 6250

 attttaatgc ttccctgcag tccaaagatg attttttcac cacaaatggt 6300

 aagggatgcc cacctacttt tataaacacc actgcaactt aacaagttta 6350

 tttatctatg tccagatttc tgtttctgtc ctaaattgat ctgtgttttt 6400

 aggtggatca acttggatct ttagacctca tctataaatt gaaattatat 6450

 ttttagtcat aagccaagta caatctaact cagaatggga ttaaaaattt 6500

 tagaagcaga agctaatata taaatgaagt ttgggatttg gaactttctg 6550

 tatctcttag gaggaacaag taaaaaccaa atggttacat tgtgctgcta 6600

 gaaataatgt cattctcaat taaaagggtt acacctgtag ccacttgaca 6650

 ctaacaccat cgagggcaat taatcaggag aaaagtaaat ataaaaactt 6700

 tgctcttaac gtcacacact acagggtaat tatgtaattc tctagcactc 6750

 aattaagaag cttgtaggtt agcaaaattt cagtttctct agttcagcca 6800

 gtgtcttgtc cttagtaatt atttgctttc cctgcagttc aatttctcct 6850

 tggaactcta acaggactaa ctggaaaaat actttgacca tagctctagt 6900

 acttccaaat aaattcatat ctagattttc aaacaaagcc ccaagatgaa 6950

 gtctaattct gaaaatatct cacaattttt gaatgttctt tttatcttac 7000

 cgacctaact tctcttttcc ctcccaactt ggcctcccac acgttccatt 7050

 tcattttggc cattatagtc acatccgttt gactttggtt gtgacatctt 7100

 cctttcagga tgatggaatt agatgcagtc tgtctttgag tgagactggt 7150

 caccatcaga ggagtttttt ctaagtgacg tgactagaag ttgaaatcta 7200

 cttccctgct aaagggcaca ggggtggtgt acaaagaaag ctaccttccc 7250

 agagcaagca ggctgcattt tagctatgga agtgacctgc tgtgacactg 7300

 tgctctcttc tgtgggctta atggttcctt tgctatgaag tggcaaatta 7350

 catgtagagt gtctccttcc ttttcagaga acagttaatc aaggcaaatc 7400

 agcaagcccc caaagtgctg taatttaaca tcatgattac caccttcgaa 7450

 gctatatatt ttgcatactt taaaatcacc taacttggac tgcttgaatt 7500

 acattggctt ttagaaccga aattgtaact atgtattgta tttcatggga 7550

 ggtatatttt atgagctttt tggctttctt ttttcccaca gcaactgcca 7600

 atgaaggatg aatccccttt ttaaaaagtt gttgttgttg ttgtttattt 7650

 gattttgagt taggagggat aatagagaag tccatttaaa aattattttt 7700

 agaagctaaa gaaagtaatt atgcttcctg tgaattgtct tttactggca 7750

 tctttgtttt cctctttgat gttagtaaat ttggtgtaat acgtggggct 7800

 tccatatttc aaagtggaag ctttcttctc tgaagtcgat atatggtttt 7850

 gaattactag agctttggtc agtatttcct tccctatatg tcacagaggg 7900

 caccactgag aactgcgtgc ataggacctc aaaatacaaa attagcaggg 7950

 cctcacagtc agcttcctca tggctagttt ttccccctta tattacaatt 8000

 tttgttttat aagtcatttt tttcctgata tttccaccac ttttcagagt 8050

 catctacaaa atttttcttt cctcaagaaa agagttcctt ttgccttatt 8100

 ccttatgcct tccccactgg tattgagggt tttgataata aattggtagg 8150

 aaaaaaaagt acctcctaga aggaagcctt ccccaccatt tccaggtgcc 8200

 aactgctaag cagatatatt ccaaaaatgg taactgtcat gtgcacactg 8250

 ttggttattt ttaataagcc tcttcctact agaacatttt attttccttg 8300

 ttcaccatac aatcatgtac tctttaacag aaattgcttt taaaaaatat 8350

 ctggaactat ctttaaaaaa actttattaa taatcatgta tttttactga 8400

 tcacattttg aaatgcctaa aagactttat tgttctaatt atccagatgt 8450

 acctttgtaa aatagctctt ttatgaatta gctgataagg ctgtatgttt 8500

 ctggaacaaa atattggtca tctaaaaact ttctgttttc tggggtctgg 8550

 gaaaatagaa aataagattt caaatattaa ataagcttaa aggaaccaag 8600

 catgtgactt ttactttgta ttctggttga tttgtcttgt ccaagttata 8650

 ttagaaaagt tgaggagtcg aggagcctgt aattaatttt cctgtcagtg 8700

 actgtcagac atcttcctgc ttattagagc atccctagca acaaggctaa 8750

 accttcatga cagtgctggc aggtgggctt gccctagcat gtggggcagg 8800

 tttgttgttt ttttaatagc tttattgaga tattcacata tcatataatt 8850

 catccattta aagtgtataa tcagatgggt tttggtatat tattgatttt 8900

 taattgtggt gaaatatata tataacaaaa tttgctattg taactatttt 8950

 taagtataaa gttcagtgag gtaggccagc ttttatgacg cacctgaaga 9000

 taactttggt tttaatccta ccctaaatga agcatatgcc tctatttttc 9050

 ctgtccccag tgctgggctt cttcacatac caacatttct gtgcttttac 9100

 caacagcatt ttagctcaga aggctcgctt actttgggca tttgctgtat 9150

 tttggttttg aaatacttgt aatttgactt attcttggga taatatttta 9200

 gttttcagtc attcaagggc acatttggct gacggagcta ataagcgtaa 9250

 taaaatgctt agtagtttat accatctttt agttaaacat tttaaagatt 9300

 aagactattc aaatgtactt tgcggaaatt aacctgtttg tatgcctggc 9350

 tttgtttaca aacatatatc tatatctata tatatagata cagatacaga 9400

 tacatatctg gtggaacaaa gaaatacctg taccattccc acttgctctt 9450

 tgatagccac ctcctaggaa tggagacaat aaaactctgt atttgcatgt 9500

 g 9501

<210> 302
<211> 1544
<212> PRT
<213> Homo sapien

<400> 302
 Met Ser Gly Thr Gln Ser Thr Ile Thr Asp Arg Phe Pro Leu Lys
   1               5                  10                  15

 Lys Pro Ile Arg His Gly Ser Ile Leu Asn Arg Glu Ser Pro Thr
                  20                  25                  30

 Asp Lys Lys Gln Lys Val Glu Arg Ile Ala Ser His Asp Phe Asp
                  35                  40                  45

 Pro Thr Asp Ser Ser Ser Lys Lys Thr Lys Ser Ser Ser Glu Glu
                  50                  55                  60

 Ser Arg Ser Glu Ile Tyr Gly Leu Val Gln Arg Cys Val Ile Ile
                  65                  70                  75

 Gln Lys Asp Asp Asn Gly Phe Gly Leu Thr Val Ser Gly Asp Asn
                  80                  85                  90

 Pro Val Phe Val Gln Ser Val Lys Glu Asp Gly Ala Ala Met Arg
                  95                 100                 105

 Ala Gly Val Gln Thr Gly Asp Arg Ile Ile Lys Val Asn Gly Thr
                 110                 115                 120

 Leu Val Thr His Ser Asn His Leu Glu Val Val Lys Leu Ile Lys
                 125                 130                 135

 Ser Gly Ser Tyr Val Ala Leu Thr Val Gln Gly Arg Pro Pro Gly
                 140                 145                 150

 Ser Pro Gln Ile Pro Leu Ala Asp Ser Glu Val Glu Pro Ser Val
                 155                 160                 165

 Ile Gly His Met Ser Pro Ile Met Thr Ser Pro His Ser Pro Gly
                 170                 175                 180

 Ala Ser Gly Asn Met Glu Arg Ile Thr Ser Pro Val Leu Met Gly
                 185                 190                 195

 Glu Glu Asn Asn Val Val His Asn Gln Lys Val Glu Ile Leu Arg
                 200                 205                 210

 Lys Met Leu Gln Lys Glu Gln Glu Arg Leu Gln Leu Leu Gln Glu
                 215                 220                 225

 Asp Tyr Asn Arg Thr Pro Ala Gln Arg Leu Leu Lys Glu Ile Gln
                 230                 235                 240

 Glu Ala Lys Lys His Ile Pro Gln Leu Gln Glu Gln Leu Ser Lys
                 245                 250                 255

 Ala Thr Gly Ser Ala Gln Asp Gly Ala Val Val Thr Pro Ser Arg
                 260                 265                 270

 Pro Leu Gly Asp Thr Leu Thr Val Ser Glu Ala Glu Thr Asp Pro
                 275                 280                 285

 Gly Asp Val Leu Gly Arg Thr Asp Cys Ser Ser Gly Asp Ala Ser
                 290                 295                 300

 Arg Pro Ser Ser Asp Asn Ala Asp Ser Pro Lys Ser Gly Pro Lys
                 305                 310                 315

 Glu Arg Ile Tyr Leu Glu Glu Asn Pro Glu Lys Ser Glu Thr Ile
                 320                 325                 330

 Gln Asp Thr Asp Thr Gln Ser Leu Val Gly Ser Pro Ser Thr Arg
                 335                 340                 345

 Ile Ala Pro His Ile Ile Gly Ala Glu Asp Asp Asp Phe Gly Thr
                 350                 355                 360

 Glu His Glu Gln Ile Asn Gly Gln Cys Ser Cys Phe Gln Ser Ile
                 365                 370                 375

 Glu Leu Leu Lys Ser Arg Pro Ala His Leu Ala Val Phe Leu His
                 380                 385                 390

 His Val Val Ser Gln Phe Asp Pro Ala Thr Leu Leu Cys Tyr Leu
                 395                 400                 405

 Tyr Ser Asp Leu Tyr Lys His Thr Asn Ser Lys Glu Thr Arg Arg
                 410                 415                 420

 Ile Phe Leu Glu Phe His Gln Phe Phe Leu Asp Arg Ser Ala His
                 425                 430                 435

 Leu Lys Val Ser Val Pro Asp Glu Met Ser Ala Asp Leu Glu Lys
                 440                 445                 450

 Arg Arg Pro Glu Leu Ile Pro Glu Asp Leu His Arg His Tyr Ile
                 455                 460                 465

 Gln Thr Met Gln Glu Arg Val His Pro Glu Val Gln Arg His Leu
                 470                 475                 480

 Glu Asp Phe Arg Gln Lys Arg Ser Met Gly Leu Thr Leu Ala Glu
                 485                 490                 495

 Ser Glu Leu Thr Lys Leu Asp Ala Glu Arg Asp Lys Asp Arg Leu
                 500                 505                 510

 Thr Leu Glu Lys Glu Arg Thr Cys Ala Glu Gln Ile Val Ala Lys
                 515                 520                 525

 Ile Glu Glu Val Leu Met Thr Ala Gln Ala Val Glu Glu Asp Lys
                 530                 535                 540

 Ser Ser Thr Met Gln Tyr Val Ile Leu Met Tyr Met Lys His Leu
                 545                 550                 555

 Gly Val Lys Val Lys Glu Pro Arg Asn Leu Glu His Lys Arg Gly
                 560                 565                 570

 Arg Ile Gly Phe Leu Pro Lys Ile Lys Gln Ser Met Lys Lys Asp
                 575                 580                 585

 Lys Glu Gly Glu Glu Lys Gly Lys Arg Arg Gly Phe Pro Ser Ile
                 590                 595                 600

 Leu Gly Pro Pro Arg Arg Pro Ser Arg His Asp Asn Ser Ala Ile
                 605                 610                 615

 Gly Arg Ala Met Glu Leu Gln Lys Ala Arg His Pro Lys His Leu
                 620                 625                 630

 Ser Thr Pro Ser Ser Val Ser Pro Glu Pro Gln Asp Ser Ala Lys
                 635                 640                 645

 Leu Arg Gln Ser Gly Leu Ala Asn Glu Gly Thr Asp Ala Gly Tyr
                 650                 655                 660

 Leu Pro Ala Asn Ser Met Ser Ser Val Ala Ser Gly Ala Ser Phe
                 665                 670                 675

 Ser Gln Glu Gly Gly Lys Glu Asn Asp Thr Gly Ser Lys Gln Val
                 680                 685                 690

 Gly Glu Thr Ser Ala Pro Gly Asp Thr Leu Asp Gly Thr Pro Arg
                 695                 700                 705

 Thr Leu Asn Thr Val Phe Asp Phe Pro Pro Pro Pro Leu Asp Gln
                 710                 715                 720

 Val Gln Glu Glu Glu Cys Glu Val Glu Arg Val Thr Glu His Gly
                 725                 730                 735

 Thr Pro Lys Pro Phe Arg Lys Phe Asp Ser Val Ala Phe Gly Glu
                 740                 745                 750

 Ser Gln Ser Glu Asp Glu Gln Phe Glu Asn Asp Leu Glu Thr Asp
                 755                 760                 765

 Pro Pro Asn Trp Gln Gln Leu Val Ser Arg Glu Val Leu Leu Gly
                 770                 775                 780

 Leu Lys Pro Cys Glu Ile Lys Arg Gln Glu Val Ile Asn Glu Leu
                 785                 790                 795

 Phe Tyr Thr Glu Arg Ala His Val Arg Thr Leu Lys Val Leu Asp
                 800                 805                 810

 Gln Val Phe Tyr Gln Arg Val Ser Arg Glu Gly Ile Leu Ser Pro
                 815                 820                 825

 Ser Glu Leu Arg Lys Ile Phe Ser Asn Leu Glu Asp Ile Leu Gln
                 830                 835                 840

 Leu His Ile Gly Leu Asn Glu Gln Met Lys Ala Val Arg Lys Arg
                 845                 850                 855

 Asn Glu Thr Ser Val Ile Asp Gln Ile Gly Glu Asp Leu Leu Thr
                 860                 865                 870

 Trp Phe Ser Gly Pro Gly Glu Glu Lys Leu Lys His Ala Ala Ala
                 875                 880                 885

 Thr Phe Cys Ser Asn Gln Pro Phe Ala Leu Glu Met Ile Lys Ser
                 890                 895                 900

 Arg Gln Lys Lys Asp Ser Arg Phe Gln Thr Phe Val Gln Asp Ala
                 905                 910                 915

 Glu Ser Asn Pro Leu Cys Arg Arg Leu Gln Leu Lys Asp Ile Ile
                 920                 925                 930

 Pro Thr Gln Met Gln Arg Leu Thr Lys Tyr Pro Leu Leu Leu Asp
                 935                 940                 945

 Asn Ile Ala Lys Tyr Thr Glu Trp Pro Thr Glu Arg Glu Lys Val
                 950                 955                 960

 Lys Lys Ala Ala Asp His Cys Arg Gln Ile Leu Asn Tyr Val Asn
                 965                 970                 975

 Gln Ala Val Lys Glu Ala Glu Asn Lys Gln Arg Leu Glu Asp Tyr
                 980                 985                 990

 Gln Arg Arg Leu Asp Thr Ser Ser Leu Lys Leu Ser Glu Tyr Pro
                 995                1000                1005

 Asn Val Glu Glu Leu Arg Asn Leu Asp Leu Thr Lys Arg Lys Met
                1010                1015                1020

 Ile His Glu Gly Pro Leu Val Trp Lys Val Asn Arg Asp Lys Thr
                1025                1030                1035

 Ile Asp Leu Tyr Thr Leu Leu Leu Glu Asp Ile Leu Val Leu Leu
                1040                1045                1050

 Gln Lys Gln Asp Asp Arg Leu Val Leu Arg Cys His Ser Lys Ile
                1055                1060                1065

 Leu Ala Ser Thr Ala Asp Ser Lys His Thr Phe Ser Pro Val Ile
                1070                1075                1080

 Lys Leu Ser Thr Val Leu Val Arg Gln Val Ala Thr Asp Asn Lys
                1085                1090                1095

 Ala Leu Phe Val Ile Ser Met Ser Asp Asn Gly Ala Gln Ile Tyr
                1100                1105                1110

 Glu Leu Val Ala Gln Thr Val Ser Glu Lys Thr Val Trp Gln Asp
                1115                1120                1125

 Leu Ile Cys Arg Met Ala Ala Ser Val Lys Glu Gln Ser Thr Lys
                1130                1135                1140

 Pro Ile Pro Leu Pro Gln Ser Thr Pro Gly Glu Gly Asp Asn Asp
                1145                1150                1155

 Glu Glu Asp Pro Ser Lys Leu Lys Glu Glu Gln His Gly Ile Ser
                1160                1165                1170

 Val Thr Gly Leu Gln Ser Pro Asp Arg Asp Leu Gly Leu Glu Ser
                1175                1180                1185

 Thr Leu Ile Ser Ser Lys Pro Gln Ser His Ser Leu Ser Thr Ser
                1190                1195                1200

 Gly Lys Ser Glu Val Arg Asp Leu Phe Val Ala Glu Arg Gln Phe
                1205                1210                1215

 Ala Lys Glu Gln His Thr Asp Gly Thr Leu Lys Glu Val Gly Glu
                1220                1225                1230

 Asp Tyr Gln Ile Ala Ile Pro Asp Ser His Leu Pro Val Ser Glu
                1235                1240                1245

 Glu Arg Trp Ala Leu Asp Ala Leu Arg Asn Leu Gly Leu Leu Lys
                1250                1255                1260

 Gln Leu Leu Val Gln Gln Leu Gly Leu Thr Glu Lys Ser Val Gln
                1265                1270                1275

 Glu Asp Trp Gln His Phe Pro Arg Tyr Arg Thr Ala Ser Gln Gly
                1280                1285                1290

 Pro Gln Thr Asp Ser Val Ile Gln Asn Ser Glu Asn Ile Lys Ala
                1295                1300                1305

 Tyr His Ser Gly Glu Gly His Met Pro Phe Arg Thr Gly Thr Gly
                1310                1315                1320

 Asp Ile Ala Thr Cys Tyr Ser Pro Arg Thr Ser Thr Glu Ser Phe
                1325                1330                1335

 Ala Pro Arg Asp Ser Val Gly Leu Ala Pro Gln Asp Ser Gln Ala
                1340                1345                1350

 Ser Asn Ile Leu Val Met Asp His Met Ile Met Thr Pro Glu Met
                1355                1360                1365

 Pro Thr Met Glu Pro Glu Gly Gly Leu Asp Asp Ser Gly Glu His
                1370                1375                1380

 Phe Phe Asp Ala Arg Glu Ala His Ser Asp Glu Asn Pro Ser Glu
                1385                1390                1395

 Gly Asp Gly Ala Val Asn Lys Glu Glu Lys Asp Val Asn Leu Arg
                1400                1405                1410

 Ile Ser Gly Asn Tyr Leu Ile Leu Asp Gly Tyr Asp Pro Val Gln
                1415                1420                1425

 Glu Ser Ser Thr Asp Glu Glu Val Ala Ser Ser Leu Thr Leu Gln
                1430                1435                1440

 Pro Met Thr Gly Ile Pro Ala Val Glu Ser Thr His Gln Gln Gln
                1445                1450                1455

 His Ser Pro Gln Asn Thr His Ser Asp Gly Ala Ile Ser Pro Phe
                1460                1465                1470

 Thr Pro Glu Phe Leu Val Gln Gln Arg Trp Gly Ala Met Glu Tyr
                1475                1480                1485

 Ser Cys Phe Glu Ile Gln Ser Pro Ser Ser Cys Ala Asp Ser Gln
                1490                1495                1500

 Ser Gln Ile Met Glu Tyr Ile His Lys Ile Glu Ala Asp Leu Glu
                1505                1510                1515

 His Leu Lys Lys Val Glu Glu Ser Tyr Thr Ile Leu Cys Gln Arg
                1520                1525                1530

 Leu Ala Gly Ser Ala Leu Thr Asp Lys His Ser Asp Lys Ser
                1535                1540

<210> 303
<211> 2528
<212> DNA
<213> Homo sapien

<400> 303
 gagttccagc agtccgcgag ctgccgtcgg ctccgcgggg ggggcgggcc 50

 gggcaccccg gggcgcggag gagcgctcct cgcttctctc cttcccccct 100

 gccgcactcc gccggaccct cccgccggcc cgcgccgctg cactcgccct 150

 ctcctctcgc cccccggcaa actttcggcc cctccccgcc cctcgcccgt 200

 tattcgtcgt ggctcaagcc cggccacgcc gccccaaggg ctcctcccga 250

 cctcccggcc tgccgctccg gccactgcgg gatccagaaa catgtcgacc 300

 acacttctgt ccgccttcta cgatgtcgac ttcttgtgca agacagagaa 350

 atccctggcc aacctcaacc tgaacaacat gctggacaag aaggcggtgg 400

 ggacgcctgt ggccgccgcc cccagctcgg gcttcgcgcc gggattcctc 450

 cgacggcact cggccagcaa cctgcatgca ctcgcccacc ccgcgcccag 500

 ccccggcagc tgctcgccca agttcccggg cgccgctaac ggcagcagct 550

 gcggcagcgc ggcggccggc ggtccgacct cctacggcac ccttaaggag 600

 ccgtcggggg gcggcggcac agccctgctc aacaaggaga acaaattccg 650

 ggaccgctcg tttagcgaga acggcgatcg cagccagcac ctcctgcacc 700

 tgcagcagca gcagaagggg ggcggcggct cccagatcaa ctccacgcgc 750

 tacaagaccg agctgtgccg gcccttcgag gagagcggca cgtgcaagta 800

 cggcgaaaag tgccagttcg cgcatggctt ccacgagctg cgcagcctga 850

 ctcgccatcc gaagtacaag accgagctgt gccgcacctt tcataccatc 900

 ggcttctgcc cctatgggcc gcgctgccac ttcatccaca acgcggacga 950

 gcggcggccc gcgccgtcgg ggggcgcctc cggggacctg cgtgcctttg 1000

 gcacgcgcga tgcgttgcac ctgggcttcc cgcgggagcc gcggcccaag 1050

 ttgcaccaca gcctcagctt ctcgggcttc ccgtcgggcc accatcagcc 1100

 cccgggcggc ctcgagtcgc cgctgctgct cgacagcccc acgtcgcgca 1150

 cgccgccgcc gccctcctgc tcttcggcct cgtcctgctc ctcctccgcc 1200

 tcctcctgtt cctcggcctc cgcggcctcc acgccctcgg gcgccccgac 1250

 atgctgcgcc tccgcggcgg ccgcggctgc ggccgctctg ctgtacggca 1300

 ccgggggcgc cgaggacctg ctggcgccgg gggccccgtg cgcggcctgc 1350

 tcgtcggcct cgtgcgccaa caacgccttc gccttcggtc cggagctcag 1400

 cagcctcatc acgccgctcg ccatccagac ccacaacttt gccgccgtgg 1450

 ccgccgccgc ctactaccgc agtcagcagc agcagcagca gcagggcctg 1500

 gcgccccccg cgcagccgcc ggcgccgccc agcgcgaccc tccccgccgg 1550

 ggccgccgca cctccctcgc cgcccttcag cttccagctg ccgcgccgcc 1600

 tgtccgactc gcccgtgttc gacgcgcccc ccagcccccc ggactcgctg 1650

 tcggaccgcg acagctacct aagcggctcc ctgagctccg gcagcctcag 1700

 cggctctgag tctcccagcc tcgaccctgg ccgccgcctg ccaatcttca 1750

 gccgcctctc catctccgac gactgaggca agagggcgcc agtgaggagg 1800

 aagggaaggc ggttcagaga tgttggagga cacccctcgc catctcgccc 1850

 ttgctggggg cacgggagtg gggggggtga catgggccct aggcagactg 1900

 caagcccgac cgagcacttg gactcgaact ctgtgccggg aggggccccc 1950

 acccctcctt tttcggtttc ctcttgtctt ttttttttta tttttattac 2000

 gaagtttcat tctttttgag caaaaaagtc gaactttttc tgttgaacaa 2050

 aatattcaca acagggcagt tgtgatacga atagaacaaa aaaaaaaaaa 2100

 aaacacttaa actttgttag gactccgatg agtttgggac ttcaggaaaa 2150

 atcaacccag caccagcagc taccaaccac cattccatct cttcacttga 2200

 acagcattag ttaagtccag atgtgggaac ccttctcttg gaagaagttc 2250

 ctaattgtgt ctcagaccgg tgtaaacaaa ccagccagcc gccaccttgc 2300

 taaacctata agctttttaa aatccaatat attctgccaa gaatatgcct 2350

 tgatagttag ccctcagccc ataggtgttt tttgtttttt aacagaatta 2400

 tatatgtctg ggggtgaaaa aacccttgca ttccaaaggt ccatactggt 2450

 tacttggttt cattgccacc acttagtgga tgttcagttt agaaccattt 2500

 tgtctgctcc ctctggaagc cttgcgca 2528

<210> 304
<211> 494
<212> PRT
<213> Homo sapien

<400> 304
 Met Ser Thr Thr Leu Leu Ser Ala Phe Tyr Asp Val Asp Phe Leu
   1               5                  10                  15

 Cys Lys Thr Glu Lys Ser Leu Ala Asn Leu Asn Leu Asn Asn Met
                  20                  25                  30

 Leu Asp Lys Lys Ala Val Gly Thr Pro Val Ala Ala Ala Pro Ser
                  35                  40                  45

 Ser Gly Phe Ala Pro Gly Phe Leu Arg Arg His Ser Ala Ser Asn
                  50                  55                  60

 Leu His Ala Leu Ala His Pro Ala Pro Ser Pro Gly Ser Cys Ser
                  65                  70                  75

 Pro Lys Phe Pro Gly Ala Ala Asn Gly Ser Ser Cys Gly Ser Ala
                  80                  85                  90

 Ala Ala Gly Gly Pro Thr Ser Tyr Gly Thr Leu Lys Glu Pro Ser
                  95                 100                 105

 Gly Gly Gly Gly Thr Ala Leu Leu Asn Lys Glu Asn Lys Phe Arg
                 110                 115                 120

 Asp Arg Ser Phe Ser Glu Asn Gly Asp Arg Ser Gln His Leu Leu
                 125                 130                 135

 His Leu Gln Gln Gln Gln Lys Gly Gly Gly Gly Ser Gln Ile Asn
                 140                 145                 150

 Ser Thr Arg Tyr Lys Thr Glu Leu Cys Arg Pro Phe Glu Glu Ser
                 155                 160                 165

 Gly Thr Cys Lys Tyr Gly Glu Lys Cys Gln Phe Ala His Gly Phe
                 170                 175                 180

 His Glu Leu Arg Ser Leu Thr Arg His Pro Lys Tyr Lys Thr Glu
                 185                 190                 195

 Leu Cys Arg Thr Phe His Thr Ile Gly Phe Cys Pro Tyr Gly Pro
                 200                 205                 210

 Arg Cys His Phe Ile His Asn Ala Asp Glu Arg Arg Pro Ala Pro
                 215                 220                 225

 Ser Gly Gly Ala Ser Gly Asp Leu Arg Ala Phe Gly Thr Arg Asp
                 230                 235                 240

 Ala Leu His Leu Gly Phe Pro Arg Glu Pro Arg Pro Lys Leu His
                 245                 250                 255

 His Ser Leu Ser Phe Ser Gly Phe Pro Ser Gly His His Gln Pro
                 260                 265                 270

 Pro Gly Gly Leu Glu Ser Pro Leu Leu Leu Asp Ser Pro Thr Ser
                 275                 280                 285

 Arg Thr Pro Pro Pro Pro Ser Cys Ser Ser Ala Ser Ser Cys Ser
                 290                 295                 300

 Ser Ser Ala Ser Ser Cys Ser Ser Ala Ser Ala Ala Ser Thr Pro
                 305                 310                 315

 Ser Gly Ala Pro Thr Cys Cys Ala Ser Ala Ala Ala Ala Ala Ala
                 320                 325                 330

 Ala Ala Leu Leu Tyr Gly Thr Gly Gly Ala Glu Asp Leu Leu Ala
                 335                 340                 345

 Pro Gly Ala Pro Cys Ala Ala Cys Ser Ser Ala Ser Cys Ala Asn
                 350                 355                 360

 Asn Ala Phe Ala Phe Gly Pro Glu Leu Ser Ser Leu Ile Thr Pro
                 365                 370                 375

 Leu Ala Ile Gln Thr His Asn Phe Ala Ala Val Ala Ala Ala Ala
                 380                 385                 390

 Tyr Tyr Arg Ser Gln Gln Gln Gln Gln Gln Gln Gly Leu Ala Pro
                 395                 400                 405

 Pro Ala Gln Pro Pro Ala Pro Pro Ser Ala Thr Leu Pro Ala Gly
                 410                 415                 420

 Ala Ala Ala Pro Pro Ser Pro Pro Phe Ser Phe Gln Leu Pro Arg
                 425                 430                 435

 Arg Leu Ser Asp Ser Pro Val Phe Asp Ala Pro Pro Ser Pro Pro
                 440                 445                 450

 Asp Ser Leu Ser Asp Arg Asp Ser Tyr Leu Ser Gly Ser Leu Ser
                 455                 460                 465

 Ser Gly Ser Leu Ser Gly Ser Glu Ser Pro Ser Leu Asp Pro Gly
                 470                 475                 480

 Arg Arg Leu Pro Ile Phe Ser Arg Leu Ser Ile Ser Asp Asp
                 485                 490

<210> 305
<211> 5533
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 95, 99, 108
<223> Unknown base

<400> 305
 cagatttacg aggttctgtt ctagtgccaa aggctcttgg tagtaaatag 50

 tgagcaaaat agatacctgt ctcctgatgg atcttgccag ccccntccnt 100

 attttttntt aagttattta ttaaaaccac acacaccttg caaagaaaaa 150

 gggaaactgg cagtctctgt agaggaagcc ggtggcatcg ctcagagcca 200

 caaactgtat ttctaaacag ccctttccct ggttccctct ctcctgcccc 250

 acttttttta aaatccagac tgtaaaaaac acatctactg acactcactt 300

 tactttaaaa aaagaagaga aaaagtaaag cgttacaaga ctttcctcct 350

 ggaaactata aactgaaaaa aaaatccata aaagattaaa tcctggcggg 400

 ttgtggggtg gcgggggccg gcggggaggg ggcgcggagt ggagattggc 450

 tctctgaggt ggtcaggggc cctgtgacag cttgggactt tcagcacctg 500

 gtttggggtc atttatctgc tcaactgtca ggacccccca cccccaaacc 550

 ccagccacca acacaaccat cgtagaaggg aacacaacac agagggtctt 600

 ttttcatttt tttaaaaaat cggtttggtt gtgtttttgt tttccatggg 650

 ggagctttaa aactcattat tgcaacacta gttccatttt tcgccagggt 700

 tccaataaca cggcatcata aaggcaacgc aacccacagt tctcaagaca 750

 tttaccacgg tcactacatc cggcagcggg gtggccccta gctcctgctg 800

 cccccccgcc ctttctcccc gcccgccccc ggagctcagc cgatttctga 850

 ggctccaact ctacccactc cctccccggg ccgccgccgc cgcgccttcc 900

 cccattctta ctccctcgag gagagccaca ggttgcaaat ccaaccaacc 950

 tcgcaatcta tttttgcaaa atcactcaca aagatctccc tttcgcgccc 1000

 gcgcccgctc ctcccgcgcc gggtcccctc agccacggcc acaaagtgcc 1050

 cttctctcct cctgagtctt gcacataagg aacgcgggct ggggctctgt 1100

 tcgtctttct cctcgcccaa ggtaaggacc tcgggaatct gaagcctggc 1150

 gtccactacg ctcaggcccg cagttccctt tttacagagc ttgcaccatg 1200

 ggaaaaaata aaataaaatt taggaaaggg aggcaacagc cattgggagc 1250

 caacacagag tcacgcagcg cccaaaatac aaacaccgca gcggccagaa 1300

 atcccgccac ctttctcgtt ctcccaggct gtcctgtcga ggttccctga 1350

 gtccccccgc acactgaaag gcatcgcagg tgcagtgcgc acccctttcc 1400

 cacccacccc aagaagccct gtcccgccat cagtctctct cctcgggatg 1450

 agcagggaga gcgcgcggag gttcccgact ccctcgacta caaccaagaa 1500

 agaataattt tcaaagtgtt caacatcccc gcccccaagc tccccaaaac 1550

 acaggggcag ggaacaccaa aacactcggc tctcgttagg aagatcacgg 1600

 ctctgaaagg aaatagtaga cacgatactt catctcatct ggatttatga 1650

 ccaaaaaaac aaaaacaaaa acccaaagag ttcgcttgca ttttttcctt 1700

 ccaaatctcg gttcggctcg aaggcaggga atctaaaaga ccgaggccga 1750

 tggaagagag ccagcggggc gagcgagcgg gcagcctccc tttttgcctc 1800

 ccggagtcac ccgttattcg tcgtggctca agcccggcca cgccgcccca 1850

 agggctcctc ccgacctccc ggcctgccgc tccggccact gcgggatcca 1900

 gaaacatgtc gaccacactt ctgtccgcct tctacgatgt cgacttcttg 1950

 tgcaagacag agaaatccct ggccaacctc aacctgaaca acatgctgga 2000

 caagaaggcg gtggggacgc ctgtggccgc cgcccccagc tcgggcttcg 2050

 cgccgggatt cctccgacgg cactcggcca gcaacctgca tgcactcgcc 2100

 caccccgcgc ccagccccgg cagctgctcg cccaagttcc cgggcgccgc 2150

 taacggcagc agctgcggca gcgcggcggc cggcggtccg acctcctacg 2200

 gcacccttaa ggagccgtcg gggggcggcg gcacagccct gctcaacaag 2250

 gagaacaaat tccgggaccg ctcgtttagc gagaacggcg atcgcagcca 2300

 gcacctcctg cacctgcagc agcagcagaa ggggggcggc ggctcccaga 2350

 tcaactccac gcgctacaag accgagctgt gccggccctt cgaggagagc 2400

 ggcacgtgca agtacggcga aaagtgccag ttcgcgcatg gcttccacga 2450

 gctgcgcagc ctgactcgcc atccgaagta caagaccgag ctgtgccgca 2500

 cctttcatac catcggcttc tgcccctatg ggccgcgctg ccacttcatc 2550

 cacaacgcgg acgagcggcg gcccgcgccg tcggggggcg cctccgggga 2600

 cctgcgtgcc tttggcacgc gcgatgcgtt gcacctgggc ttcccgcggg 2650

 agccgcggcc caagttgcac cacagcctca gcttctcggg cttcccgtcg 2700

 ggccaccatc agcccccggg cggcctcgag tcgccgctgc tgctcgacag 2750

 ccccacgtcg cgcacgccgc cgccgccctc ctgctcttcg gcctcgtcct 2800

 gctcctcctc cgcctcctcc tgttcctcgg cctccgcggc ctccacgccc 2850

 tcgggcgccc cgacatgctg cgcctccgcg gcggccgcgg ctgcggccgc 2900

 tctgctgtac ggcaccgggg gcgccgagga cctgctggcg ccgggggccc 2950

 cgtgcgcggc ctgctcgtcg gcctcgtgcg ccaacaacgc cttcgccttc 3000

 ggtccggagc tcagcagcct catcacgccg ctcgccatcc agacccacaa 3050

 ctttgccgcc gtggccgccg ccgcctacta ccgcagtcag cagcagcagc 3100

 agcagcaggg cctggcgccc cccgcgcagc cgccggcgcc gcccagcgcg 3150

 accctccccg ccggggccgc cgcacctccc tcgccgccct tcagcttcca 3200

 gctgccgcgc cgcctgtccg actcgcccgt gttcgacgcg ccccccagcc 3250

 ccccggactc gctgtcggac cgcgacagct acctaagcgg ctccctgagc 3300

 tccggcagcc tcagcggctc tgagtctccc agcctcgacc ctggccgccg 3350

 cctgccaatc ttcagccgcc tctccatctc cgacgactga ggcaagaggg 3400

 cgccagtgag gaggaaggga aggcggttca gagatgttgg aggacacccc 3450

 tcgccatctc gcccttgctg ggggcacggg agtggggggg gtgacatggg 3500

 ccctaggcag actgcaagcc cgaccgagca cttggactcg aactctgtgc 3550

 cgggaggggc ccccacccct cctttttcgg tttcctcttg tctctttttt 3600

 tttattttta ttacgaagtt tcattctttt tgagcaaaaa agtcgaactt 3650

 tttctgttga acaaaatatt cacaacaggg cagttgtgat acgaatagaa 3700

 caaaaaagaa aaaaaaaaca cttaaacttt gttaggactc cgatgagttt 3750

 gggacttcag gaaaaatcaa cccagcacca gcagctacca accaccattc 3800

 catctcttca cttgaacagc attagttaag tccagatgtg ggaacccttc 3850

 tcttggaaga agttcctaat tgtgtctcag accggtgtaa acaaaccagc 3900

 cagccgccac cttgctaaac ctataagctt tttaaaatcc aatatattct 3950

 gccaagaata tgccttgata gttagccctc agcccatagg tgttttttgt 4000

 tttttaacag aattatatat gtctgggggt gaaaaaaccc ttgcattcca 4050

 aaggtccata ctggttactt ggtttcattg ccaccactta gtggatgttc 4100

 agtttagaac cattttgtct gctccctctg gaagccttgc gcagagctta 4150

 ctttgtaatt gttggagaat aactgctgaa tttttagctg ttttgagttg 4200

 attcgcacca ctgcaccaca actcaatatg aaaactattt aacttattta 4250

 ttatcttgtg aaaagtatac aatgaaaatt ttgttcatac tgtatttatc 4300

 aagtatgatg aaaagcaata gatatatatt cttttattat gttaaattat 4350

 gattgccatt attaatcggc aaaatgtgga gtgtatgttc ttttcacagt 4400

 aatatatgcc ttttgtaact tcacttggtt attttattgt aaatgagtac 4450

 aaaattctta atttaagaga ttgtatgtaa tatttatttc attaatttct 4500

 ttccttgttt acgtaaattt tgaaagattg catgatttct tgacagaaat 4550

 cgatcttgat gctgtggaag tagtttgagg aacatcctat gagttttctt 4600

 agaatgtata aaggttgtag cccatccaac ttcaaagaaa aaaatgacca 4650

 catactttgc aatcaggctg aaatgtggca tgcttttcta attccaactt 4700

 tataaactag caaaaaagtg tttgcttatt ccaccagttc tactgtgaca 4750

 tactcgagta taaagacatg tagcaataac ggggagtggg gggggagtct 4800

 cacagtgcct ttggaagggc ccgaacttgc cttaaatctt cctcaaccaa 4850

 ataagtattt tattagtgct tgagagaatc tgaatgtagg atgggttcaa 4900

 ctgcacaaaa ggaaaagatt tttaccactt tttttatata gatataaagt 4950

 gaagcaaccg ccttagtgct gaaatatgta gtacatgaat atgccttgtt 5000

 taattacaga aaattccaaa acttgtacta tttttttttt ccatgtagaa 5050

 aggcaggaat gtctcctaag ctttcctgga cagcagatga atgagcggta 5100

 gctttagttt gtacgtaggt acagttggag cactatatgt actctctgga 5150

 ctactttgga cagaagtagg tttttgaatg taacaagata agtcaacttg 5200

 agttgtaata tattttgggg aatcagctca ctacaaattg tgactgtaaa 5250

 cattgtactg taaatgtttt gtagttttcc cccaataaaa tttttgggaa 5300

 aaaaaggtat taacatgtaa gagctttctt tttaaacagg aatgtcttag 5350

 ctttctagct tcccagctaa ccatgtctgc cattccccag gtcttggcat 5400

 ggtgggggag gacttggaga gctggcagag ccagagttca gaagagcctg 5450

 cgtcctctca gcccgtatat attttataag caagttcttc taatgaaaga 5500

 aagtaattat ttggactgtc aagggcatta gtt 5533

<210> 306
<211> 546
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 95, 99, 108
<223> Unknown amino acid

<400> 306
 Met Glu Glu Ser Gln Arg Gly Glu Arg Ala Gly Ser Leu Pro Phe
   1               5                  10                  15

 Cys Leu Pro Glu Ser Pro Val Ile Arg Arg Gly Ser Ser Pro Ala
                  20                  25                  30

 Thr Pro Pro Gln Gly Leu Leu Pro Thr Ser Arg Pro Ala Ala Pro
                  35                  40                  45

 Ala Thr Ala Gly Ser Arg Asn Met Ser Thr Thr Leu Leu Ser Ala
                  50                  55                  60

 Phe Tyr Asp Val Asp Phe Leu Cys Lys Thr Glu Lys Ser Leu Ala
                  65                  70                  75

 Asn Leu Asn Leu Asn Asn Met Leu Asp Lys Lys Ala Val Gly Thr
                  80                  85                  90

 Pro Val Ala Ala Ala Pro Ser Ser Gly Phe Ala Pro Gly Phe Leu
                  95                 100                 105

 Arg Arg His Ser Ala Ser Asn Leu His Ala Leu Ala His Pro Ala
                 110                 115                 120

 Pro Ser Pro Gly Ser Cys Ser Pro Lys Phe Pro Gly Ala Ala Asn
                 125                 130                 135

 Gly Ser Ser Cys Gly Ser Ala Ala Ala Gly Gly Pro Thr Ser Tyr
                 140                 145                 150

 Gly Thr Leu Lys Glu Pro Ser Gly Gly Gly Gly Thr Ala Leu Leu
                 155                 160                 165

 Asn Lys Glu Asn Lys Phe Arg Asp Arg Ser Phe Ser Glu Asn Gly
                 170                 175                 180

 Asp Arg Ser Gln His Leu Leu His Leu Gln Gln Gln Gln Lys Gly
                 185                 190                 195

 Gly Gly Gly Ser Gln Ile Asn Ser Thr Arg Tyr Lys Thr Glu Leu
                 200                 205                 210

 Cys Arg Pro Phe Glu Glu Ser Gly Thr Cys Lys Tyr Gly Glu Lys
                 215                 220                 225

 Cys Gln Phe Ala His Gly Phe His Glu Leu Arg Ser Leu Thr Arg
                 230                 235                 240

 His Pro Lys Tyr Lys Thr Glu Leu Cys Arg Thr Phe His Thr Ile
                 245                 250                 255

 Gly Phe Cys Pro Tyr Gly Pro Arg Cys His Phe Ile His Asn Ala
                 260                 265                 270

 Asp Glu Arg Arg Pro Ala Pro Ser Gly Gly Ala Ser Gly Asp Leu
                 275                 280                 285

 Arg Ala Phe Gly Thr Arg Asp Ala Leu His Leu Gly Phe Pro Arg
                 290                 295                 300

 Glu Pro Arg Pro Lys Leu His His Ser Leu Ser Phe Ser Gly Phe
                 305                 310                 315

 Pro Ser Gly His His Gln Pro Pro Gly Gly Leu Glu Ser Pro Leu
                 320                 325                 330

 Leu Leu Asp Ser Pro Thr Ser Arg Thr Pro Pro Pro Pro Ser Cys
                 335                 340                 345

 Ser Ser Ala Ser Ser Cys Ser Ser Ser Ala Ser Ser Cys Ser Ser
                 350                 355                 360

 Ala Ser Ala Ala Ser Thr Pro Ser Gly Ala Pro Thr Cys Cys Ala
                 365                 370                 375

 Ser Ala Ala Ala Ala Ala Ala Ala Ala Leu Leu Tyr Gly Thr Gly
                 380                 385                 390

 Gly Ala Glu Asp Leu Leu Ala Pro Gly Ala Pro Cys Ala Ala Cys
                 395                 400                 405

 Ser Ser Ala Ser Cys Ala Asn Asn Ala Phe Ala Phe Gly Pro Glu
                 410                 415                 420

 Leu Ser Ser Leu Ile Thr Pro Leu Ala Ile Gln Thr His Asn Phe
                 425                 430                 435

 Ala Ala Val Ala Ala Ala Ala Tyr Tyr Arg Ser Gln Gln Gln Gln
                 440                 445                 450

 Gln Gln Gln Gly Leu Ala Pro Pro Ala Gln Pro Pro Ala Pro Pro
                 455                 460                 465

 Ser Ala Thr Leu Pro Ala Gly Ala Ala Ala Pro Pro Ser Pro Pro
                 470                 475                 480

 Phe Ser Phe Gln Leu Pro Arg Arg Leu Ser Asp Ser Pro Val Phe
                 485                 490                 495

 Asp Ala Pro Pro Ser Pro Pro Asp Ser Leu Ser Asp Arg Asp Ser
                 500                 505                 510

 Tyr Leu Ser Gly Ser Leu Ser Ser Gly Ser Leu Ser Gly Ser Glu
                 515                 520                 525

 Ser Pro Ser Leu Asp Pro Gly Arg Arg Leu Pro Ile Phe Ser Arg
                 530                 535                 540

 Leu Ser Ile Ser Asp Asp
                 545

<210> 307
<211> 2528
<212> DNA
<213> Homo sapien

<400> 307
 gagttccagc agtccgcgag ctgccgtcgg ctccgcgggg ggggcgggcc 50

 gggcaccccg gggcgcggag gagcgctcct cgcttctctc cttcccccct 100

 gccgcactcc gccggaccct cccgccggcc cgcgccgctg cactcgccct 150

 ctcctctcgc cccccggcaa actttcggcc cctccccgcc cctcgcccgt 200

 tattcgtcgt ggctcaagcc cggccacgcc gccccaaggg ctcctcccga 250

 cctcccggcc tgccgctccg gccactgcgg gatccagaaa catgtcgacc 300

 acacttctgt ccgccttcta cgatgtcgac ttcttgtgca agacagagaa 350

 atccctggcc aacctcaacc tgaacaacat gctggacaag aaggcggtgg 400

 ggacgcctgt ggccgccgcc cccagctcgg gcttcgcgcc gggattcctc 450

 cgacggcact cggccagcaa cctgcatgca ctcgcccacc ccgcgcccag 500

 ccccggcagc tgctcgccca agttcccggg cgccgctaac ggcagcagct 550

 gcggcagcgc ggcggccggc ggtccgacct cctacggcac ccttaaggag 600

 ccgtcggggg gcggcggcac agccctgctc aacaaggaga acaaattccg 650

 ggaccgctcg tttagcgaga acggcgatcg cagccagcac ctcctgcacc 700

 tgcagcagca gcagaagggg ggcggcggct cccagatcaa ctccacgcgc 750

 tacaagaccg agctgtgccg gcccttcgag gagagcggca cgtgcaagta 800

 cggcgaaaag tgccagttcg cgcatggctt ccacgagctg cgcagcctga 850

 ctcgccatcc gaagtacaag accgagctgt gccgcacctt tcataccatc 900

 ggcttctgcc cctatgggcc gcgctgccac ttcatccaca acgcggacga 950

 gcggcggccc gcgccgtcgg ggggcgcctc cggggacctg cgtgcctttg 1000

 gcacgcgcga tgcgttgcac ctgggcttcc cgcgggagcc gcggcccaag 1050

 ttgcaccaca gcctcagctt ctcgggcttc ccgtcgggcc accatcagcc 1100

 cccgggcggc ctcgagtcgc cgctgctgct cgacagcccc acgtcgcgca 1150

 cgccgccgcc gccctcctgc tcttcggcct cgtcctgctc ctcctccgcc 1200

 tcctcctgtt cctcggcctc cgcggcctcc acgccctcgg gcgccccgac 1250

 atgctgcgcc tccgcggcgg ccgcggctgc ggccgctctg ctgtacggca 1300

 ccgggggcgc cgaggacctg ctggcgccgg gggccccgtg cgcggcctgc 1350

 tcgtcggcct cgtgcgccaa caacgccttc gccttcggtc cggagctcag 1400

 cagcctcatc acgccgctcg ccatccagac ccacaacttt gccgccgtgg 1450

 ccgccgccgc ctactaccgc agtcagcagc agcagcagca gcagggcctg 1500

 gcgccccccg cgcagccgcc ggcgccgccc agcgcgaccc tccccgccgg 1550

 ggccgccgca cctccctcgc cgcccttcag cttccagctg ccgcgccgcc 1600

 tgtccgactc gcccgtgttc gacgcgcccc ccagcccccc ggactcgctg 1650

 tcggaccgcg acagctacct aagcggctcc ctgagctccg gcagcctcag 1700

 cggctctgag tctcccagcc tcgaccctgg ccgccgcctg ccaatcttca 1750

 gccgcctctc catctccgac gactgaggca agagggcgcc agtgaggagg 1800

 aagggaaggc ggttcagaga tgttggagga cacccctcgc catctcgccc 1850

 ttgctggggg cacgggagtg gggggggtga catgggccct aggcagactg 1900

 caagcccgac cgagcacttg gactcgaact ctgtgccggg aggggccccc 1950

 acccctcctt tttcggtttc ctcttgtctt ttttttttta tttttattac 2000

 gaagtttcat tctttttgag caaaaaagtc gaactttttc tgttgaacaa 2050

 aatattcaca acagggcagt tgtgatacga atagaacaaa aaaaaaaaaa 2100

 aaacacttaa actttgttag gactccgatg agtttgggac ttcaggaaaa 2150

 atcaacccag caccagcagc taccaaccac cattccatct cttcacttga 2200

 acagcattag ttaagtccag atgtgggaac ccttctcttg gaagaagttc 2250

 ctaattgtgt ctcagaccgg tgtaaacaaa ccagccagcc gccaccttgc 2300

 taaacctata agctttttaa aatccaatat attctgccaa gaatatgcct 2350

 tgatagttag ccctcagccc ataggtgttt tttgtttttt aacagaatta 2400

 tatatgtctg ggggtgaaaa aacccttgca ttccaaaggt ccatactggt 2450

 tacttggttt cattgccacc acttagtgga tgttcagttt agaaccattt 2500

 tgtctgctcc ctctggaagc cttgcgca 2528

<210> 308
<211> 494
<212> PRT
<213> Homo sapien

<400> 308
 Met Ser Thr Thr Leu Leu Ser Ala Phe Tyr Asp Val Asp Phe Leu
   1               5                  10                  15

 Cys Lys Thr Glu Lys Ser Leu Ala Asn Leu Asn Leu Asn Asn Met
                  20                  25                  30

 Leu Asp Lys Lys Ala Val Gly Thr Pro Val Ala Ala Ala Pro Ser
                  35                  40                  45

 Ser Gly Phe Ala Pro Gly Phe Leu Arg Arg His Ser Ala Ser Asn
                  50                  55                  60

 Leu His Ala Leu Ala His Pro Ala Pro Ser Pro Gly Ser Cys Ser
                  65                  70                  75

 Pro Lys Phe Pro Gly Ala Ala Asn Gly Ser Ser Cys Gly Ser Ala
                  80                  85                  90

 Ala Ala Gly Gly Pro Thr Ser Tyr Gly Thr Leu Lys Glu Pro Ser
                  95                 100                 105

 Gly Gly Gly Gly Thr Ala Leu Leu Asn Lys Glu Asn Lys Phe Arg
                 110                 115                 120

 Asp Arg Ser Phe Ser Glu Asn Gly Asp Arg Ser Gln His Leu Leu
                 125                 130                 135

 His Leu Gln Gln Gln Gln Lys Gly Gly Gly Gly Ser Gln Ile Asn
                 140                 145                 150

 Ser Thr Arg Tyr Lys Thr Glu Leu Cys Arg Pro Phe Glu Glu Ser
                 155                 160                 165

 Gly Thr Cys Lys Tyr Gly Glu Lys Cys Gln Phe Ala His Gly Phe
                 170                 175                 180

 His Glu Leu Arg Ser Leu Thr Arg His Pro Lys Tyr Lys Thr Glu
                 185                 190                 195

 Leu Cys Arg Thr Phe His Thr Ile Gly Phe Cys Pro Tyr Gly Pro
                 200                 205                 210

 Arg Cys His Phe Ile His Asn Ala Asp Glu Arg Arg Pro Ala Pro
                 215                 220                 225

 Ser Gly Gly Ala Ser Gly Asp Leu Arg Ala Phe Gly Thr Arg Asp
                 230                 235                 240

 Ala Leu His Leu Gly Phe Pro Arg Glu Pro Arg Pro Lys Leu His
                 245                 250                 255

 His Ser Leu Ser Phe Ser Gly Phe Pro Ser Gly His His Gln Pro
                 260                 265                 270

 Pro Gly Gly Leu Glu Ser Pro Leu Leu Leu Asp Ser Pro Thr Ser
                 275                 280                 285

 Arg Thr Pro Pro Pro Pro Ser Cys Ser Ser Ala Ser Ser Cys Ser
                 290                 295                 300

 Ser Ser Ala Ser Ser Cys Ser Ser Ala Ser Ala Ala Ser Thr Pro
                 305                 310                 315

 Ser Gly Ala Pro Thr Cys Cys Ala Ser Ala Ala Ala Ala Ala Ala
                 320                 325                 330

 Ala Ala Leu Leu Tyr Gly Thr Gly Gly Ala Glu Asp Leu Leu Ala
                 335                 340                 345

 Pro Gly Ala Pro Cys Ala Ala Cys Ser Ser Ala Ser Cys Ala Asn
                 350                 355                 360

 Asn Ala Phe Ala Phe Gly Pro Glu Leu Ser Ser Leu Ile Thr Pro
                 365                 370                 375

 Leu Ala Ile Gln Thr His Asn Phe Ala Ala Val Ala Ala Ala Ala
                 380                 385                 390

 Tyr Tyr Arg Ser Gln Gln Gln Gln Gln Gln Gln Gly Leu Ala Pro
                 395                 400                 405

 Pro Ala Gln Pro Pro Ala Pro Pro Ser Ala Thr Leu Pro Ala Gly
                 410                 415                 420

 Ala Ala Ala Pro Pro Ser Pro Pro Phe Ser Phe Gln Leu Pro Arg
                 425                 430                 435

 Arg Leu Ser Asp Ser Pro Val Phe Asp Ala Pro Pro Ser Pro Pro
                 440                 445                 450

 Asp Ser Leu Ser Asp Arg Asp Ser Tyr Leu Ser Gly Ser Leu Ser
                 455                 460                 465

 Ser Gly Ser Leu Ser Gly Ser Glu Ser Pro Ser Leu Asp Pro Gly
                 470                 475                 480

 Arg Arg Leu Pro Ile Phe Ser Arg Leu Ser Ile Ser Asp Asp
                 485                 490

<210> 309
<211> 2435
<212> DNA
<213> Homo sapien

<400> 309
 gcagcgccgc gactcgtgcg ggtaggcgtc tgcgctcggt ttgagggctc 50

 ggcgcggggt ttcctgttcc tccttctgcg cggctgcagc tcgggacttc 100

 ggcctgaccc agcccccatg gcttcagaag agctacagaa agatctagaa 150

 gaggtaaagg tgttgctgga aaaggctact aggaaaagag tacgtgatgc 200

 ccttacagct gaaaaatcca agattgagac agaaatcaag aacaagatgc 250

 aacagaaatc acagaagaaa gcagaacttc ttgataatga aaaaccagct 300

 gctgtggttg ctcccattac aacgggctat acggtgaaaa tcagtaatta 350

 tggatgggat cagtcagata agtttgtgaa aatctacatt accttaactg 400

 gagttcatca agttcccact gagaatgtgc aggtgcattt cacagagagg 450

 tcatttgatc ttttggtaaa gaatctaaat gggaagagtt actccatgat 500

 tgtgaacaat ctcttgaaac ccatctctgt ggaaggcagt tcaaaaaaag 550

 tcaagactga tacagttctt atattgtgta gaaagaaagt ggaaaacaca 600

 aggtgggatt acctgaccca ggttgaaaag gagtgcaaag aaaaagagaa 650

 gccctcctat gacactgaaa cagatcctag tgagggattg atgaatgttc 700

 taaagaaaat ttatgaagat ggagacgatg atatgaagcg aaccattaat 750

 aaagcctggg tggaatcaag agagaagcaa gccaaaggag acacggaatt 800

 ttgagacttt aaagtcgttt tgggaactgt gatgtgatgt ggaaatactg 850

 atgtttccag taagggaata ttggtgagct gcatatataa atttgacaga 900

 tagctattta catagccttc taagtaaagg caatgaattc tccatttcct 950

 actggaggat ttatttaaat aaaatatgct tattaaacac tcctgcaaag 1000

 atggttttat tagtaccctg gtcattttgt tcaaggaagg gttatattgc 1050

 attctcacgt gaaatataaa aagcaagtct tgcccaataa aaacgctaca 1100

 ttgtgtgtat tttttgttca gctaagaatt ggaaaagtat ttgcttgcct 1150

 tttaagttac tgacatcagc ttccaccagt gtaaaaattg agtaaaacct 1200

 gaagttttgc ataaaatgca aatcggtgcc tgtgcttgaa ggttgctgta 1250

 gagcatctga ccccttatta ccaccttaag caatgtatat gccatgcatt 1300

 accatgcact aattcaatca caggtgtttc tatctagatt taaatatatt 1350

 tgtcaatgaa tgtggaatag aaaatctaaa catgacaata atagacatat 1400

 ctttgtatgg taccagttag ttttgccgtg gatcagatgg tttataaaag 1450

 taataaccat aaagcaaaaa ataatttgaa agcccgtcta ttcctatgct 1500

 caataaagtt aagtttttct tcattagaac agttttatga tttatttgtc 1550

 taggagtatg tcagaaaaat caggctttta gtaggaatta ctcctattcc 1600

 ccctgaagtc aggaccagtg cctgtgatct ccattacttt attttcctgg 1650

 aggtattagc caacacagtt agatcagaga aagcaattga agccaggcat 1700

 gaaggctggc gcccgtaatc ccagctacta aggctggagg atcacttcag 1750

 cccaggagtt taaggctgca gtgagctatg atgatgccac tgtactgcag 1800

 cttgggtaac agattgagaa cctgtctcat taaaaaaaaa aaaaaaaaaa 1850

 aagccgttag acacacagga aaaatccaga agggtaaact aaactaaagc 1900

 tacaattaat atgggaattt ggaagaagtg gtaggattta aaatacagaa 1950

 acagtttatg tataggatag ctataagtaa atactgaaac acattatgcc 2000

 tctgtaattg gggttgacac atgaacagaa tagcagacac aatgcatatg 2050

 aaagttacag aatatggtaa aagtggggta aagatgggtt tttaatgata 2100

 ctaagataac tgaaaatagg catatagata tattccaagc cgcctgacga 2150

 tctaattgta aaaagtaaag catacaaata ctagaagaaa atggaggaaa 2200

 acgacattat atgtgactta aaacctagaa gaaataaata aaactattga 2250

 tcaattttaa ctacataaaa atgtttatag gacaagaaaa accccaccat 2300

 aacccaaggc aaacaatgta ttgacaggat tccaataatt aagaatactt 2350

 catacaaaaa gaaatgtaaa tgacctttaa catgtaaaga tgctcacctt 2400

 gttcagaaga gaataaacca gtgtttttac ctttc 2435

<210> 310
<211> 228
<212> PRT
<213> Homo sapien

<400> 310
 Met Ala Ser Glu Glu Leu Gln Lys Asp Leu Glu Glu Val Lys Val
   1               5                  10                  15

 Leu Leu Glu Lys Ala Thr Arg Lys Arg Val Arg Asp Ala Leu Thr
                  20                  25                  30

 Ala Glu Lys Ser Lys Ile Glu Thr Glu Ile Lys Asn Lys Met Gln
                  35                  40                  45

 Gln Lys Ser Gln Lys Lys Ala Glu Leu Leu Asp Asn Glu Lys Pro
                  50                  55                  60

 Ala Ala Val Val Ala Pro Ile Thr Thr Gly Tyr Thr Val Lys Ile
                  65                  70                  75

 Ser Asn Tyr Gly Trp Asp Gln Ser Asp Lys Phe Val Lys Ile Tyr
                  80                  85                  90

 Ile Thr Leu Thr Gly Val His Gln Val Pro Thr Glu Asn Val Gln
                  95                 100                 105

 Val His Phe Thr Glu Arg Ser Phe Asp Leu Leu Val Lys Asn Leu
                 110                 115                 120

 Asn Gly Lys Ser Tyr Ser Met Ile Val Asn Asn Leu Leu Lys Pro
                 125                 130                 135

 Ile Ser Val Glu Gly Ser Ser Lys Lys Val Lys Thr Asp Thr Val
                 140                 145                 150

 Leu Ile Leu Cys Arg Lys Lys Val Glu Asn Thr Arg Trp Asp Tyr
                 155                 160                 165

 Leu Thr Gln Val Glu Lys Glu Cys Lys Glu Lys Glu Lys Pro Ser
                 170                 175                 180

 Tyr Asp Thr Glu Thr Asp Pro Ser Glu Gly Leu Met Asn Val Leu
                 185                 190                 195

 Lys Lys Ile Tyr Glu Asp Gly Asp Asp Asp Met Lys Arg Thr Ile
                 200                 205                 210

 Asn Lys Ala Trp Val Glu Ser Arg Glu Lys Gln Ala Lys Gly Asp
                 215                 220                 225

 Thr Glu Phe


<210> 311
<211> 2174
<212> DNA
<213> Homo sapien

<400> 311
 agaaggccca gcgccgggaa ggggtttgca gctgctccgt catcgtgcgg 50

 cccgacgcta tctcgcgctc gtgtgcaggc ccggctcggc tcctggtccc 100

 cggtgcgagg gttaacgcga ggccccggcc tcggtccccg gactaggccg 150

 tgaccccggg tgccatgaag caggagggct cggcgcggcg ccgcggcgcg 200

 gacaaggcga aaccgccgcc cggcggagga gaacaagaac ccccaccgcc 250

 gccggccccc caggatgtgg agatgaaaga ggaggcagcg acgggtggcg 300

 ggtcgacggg ggaggcagac ggcaagacgg cggcggcagc ggctgagcac 350

 tcccagcgag agctggacac agtcaccttg gaggacatca aggagcacgt 400

 gaaacagcta gagaaagcgg tttcaggcaa ggagccgaga ttcgtgctgc 450

 gggccctgcg gatgctgcct tccacatcac gccgcctcaa ccactatgtt 500

 ctgtataagg ctgtgcaggg cttcttcact tcaaataatg ccactcgaga 550

 ctttttgctc cccttcctgg aagagcccat ggacacagag gctgatttac 600

 agttccgtcc ccgcacggga aaagctgcgt cgacacccct cctgcctgaa 650

 gtggaagcct atctccaact cctcgtggtc atcttcatga tgaacagcaa 700

 gcgctacaaa gaggcacaga agatctctga tgatctgatg cagaagatca 750

 gtactcagaa ccgccgggcc ctagaccttg tagccgcaaa gtgttactat 800

 tatcacgccc gggtctatga gttcctggac aagctggatg tggtgcgcag 850

 cttcttgcat gctcggctcc ggacagctac gcttcggcat gacgcagacg 900

 ggcaggccac cctgttgaac ctcctgctgc ggaattacct acactacagc 950

 ttgtacgacc aggctgagaa gctggtgtcc aagtctgtgt tcccagagca 1000

 ggccaacaac aatgagtggg ccaggtacct ctactacaca gggcgaatca 1050

 aagccatcca gctggagtac tcagaggccc ggagaacgat gaccaacgcc 1100

 cttcgcaagg cccctcagca cacagctgtc ggcttcaaac agacggtgca 1150

 caagcttctc atcgtggtgg agctgttgct gggggagatc cctgaccggc 1200

 tgcagttccg ccagccctcc ctcaagcgct cactcatgcc ctatttcctt 1250

 ctgactcaag ctgtcaggac aggaaaccta gccaagttca accaggtcct 1300

 ggatcagttt ggggagaagt ttcaagcaga tgggacctac accctaatta 1350

 tccggctgcg gcacaacgtg attaagacag gtgtacgcat gatcagcctc 1400

 tcctattccc gaatctcctt ggctgacatc gcccagaagc tgcagttgga 1450

 tagccccgaa gatgcagagt tcattgttgc caaggccatc cgggatggtg 1500

 tcattgaggc cagcatcaac cacgagaagg gctatgtcca atccaaggag 1550

 atgattgaca tctattccac ccgagagccc cagctagcct tccaccagcg 1600

 catctccttc tgcctagata tccacaacat gtctgtcaag gccatgaggt 1650

 ttcctcccaa atcgtacaac aaggacttgg agtctgcaga ggaacggcgt 1700

 gagcgagaac agcaggactt ggagtttgcc aaggagatgg cagaagatga 1750

 tgatgacagc ttcccttgag ctggggggct ggggaggggt agggggaatg 1800

 gggacaggct ctttccccct tgggggtccc ctgcccaggg cactgtcccc 1850

 attttcccac acacagctca tatgctgcat tcgtgcaggg ggtgggggtg 1900

 ctgggagcca gccaccctga cctcccccag ggctcctccc cagccggtga 1950

 cttactgtac agcaggcagg agggtgggca ggcaacctcc ccgggcaggg 2000

 tcctggccag cagtgtggga gcaggagggg aaggatagtt ctgtgtactc 2050

 ctttagggag tgggggacta gaactgggat gtcttggctt gtatgttttt 2100

 tgaagcttcg attatgattt ttaaacaata aaaagttctc cacagtgaaa 2150

 aaaaaaaaaa aaaaaaaaaa aaaa 2174

<210> 312
<211> 534
<212> PRT
<213> Homo sapien

<400> 312
 Met Lys Gln Glu Gly Ser Ala Arg Arg Arg Gly Ala Asp Lys Ala
   1               5                  10                  15

 Lys Pro Pro Pro Gly Gly Gly Glu Gln Glu Pro Pro Pro Pro Pro
                  20                  25                  30

 Ala Pro Gln Asp Val Glu Met Lys Glu Glu Ala Ala Thr Gly Gly
                  35                  40                  45

 Gly Ser Thr Gly Glu Ala Asp Gly Lys Thr Ala Ala Ala Ala Ala
                  50                  55                  60

 Glu His Ser Gln Arg Glu Leu Asp Thr Val Thr Leu Glu Asp Ile
                  65                  70                  75

 Lys Glu His Val Lys Gln Leu Glu Lys Ala Val Ser Gly Lys Glu
                  80                  85                  90

 Pro Arg Phe Val Leu Arg Ala Leu Arg Met Leu Pro Ser Thr Ser
                  95                 100                 105

 Arg Arg Leu Asn His Tyr Val Leu Tyr Lys Ala Val Gln Gly Phe
                 110                 115                 120

 Phe Thr Ser Asn Asn Ala Thr Arg Asp Phe Leu Leu Pro Phe Leu
                 125                 130                 135

 Glu Glu Pro Met Asp Thr Glu Ala Asp Leu Gln Phe Arg Pro Arg
                 140                 145                 150

 Thr Gly Lys Ala Ala Ser Thr Pro Leu Leu Pro Glu Val Glu Ala
                 155                 160                 165

 Tyr Leu Gln Leu Leu Val Val Ile Phe Met Met Asn Ser Lys Arg
                 170                 175                 180

 Tyr Lys Glu Ala Gln Lys Ile Ser Asp Asp Leu Met Gln Lys Ile
                 185                 190                 195

 Ser Thr Gln Asn Arg Arg Ala Leu Asp Leu Val Ala Ala Lys Cys
                 200                 205                 210

 Tyr Tyr Tyr His Ala Arg Val Tyr Glu Phe Leu Asp Lys Leu Asp
                 215                 220                 225

 Val Val Arg Ser Phe Leu His Ala Arg Leu Arg Thr Ala Thr Leu
                 230                 235                 240

 Arg His Asp Ala Asp Gly Gln Ala Thr Leu Leu Asn Leu Leu Leu
                 245                 250                 255

 Arg Asn Tyr Leu His Tyr Ser Leu Tyr Asp Gln Ala Glu Lys Leu
                 260                 265                 270

 Val Ser Lys Ser Val Phe Pro Glu Gln Ala Asn Asn Asn Glu Trp
                 275                 280                 285

 Ala Arg Tyr Leu Tyr Tyr Thr Gly Arg Ile Lys Ala Ile Gln Leu
                 290                 295                 300

 Glu Tyr Ser Glu Ala Arg Arg Thr Met Thr Asn Ala Leu Arg Lys
                 305                 310                 315

 Ala Pro Gln His Thr Ala Val Gly Phe Lys Gln Thr Val His Lys
                 320                 325                 330

 Leu Leu Ile Val Val Glu Leu Leu Leu Gly Glu Ile Pro Asp Arg
                 335                 340                 345

 Leu Gln Phe Arg Gln Pro Ser Leu Lys Arg Ser Leu Met Pro Tyr
                 350                 355                 360

 Phe Leu Leu Thr Gln Ala Val Arg Thr Gly Asn Leu Ala Lys Phe
                 365                 370                 375

 Asn Gln Val Leu Asp Gln Phe Gly Glu Lys Phe Gln Ala Asp Gly
                 380                 385                 390

 Thr Tyr Thr Leu Ile Ile Arg Leu Arg His Asn Val Ile Lys Thr
                 395                 400                 405

 Gly Val Arg Met Ile Ser Leu Ser Tyr Ser Arg Ile Ser Leu Ala
                 410                 415                 420

 Asp Ile Ala Gln Lys Leu Gln Leu Asp Ser Pro Glu Asp Ala Glu
                 425                 430                 435

 Phe Ile Val Ala Lys Ala Ile Arg Asp Gly Val Ile Glu Ala Ser
                 440                 445                 450

 Ile Asn His Glu Lys Gly Tyr Val Gln Ser Lys Glu Met Ile Asp
                 455                 460                 465

 Ile Tyr Ser Thr Arg Glu Pro Gln Leu Ala Phe His Gln Arg Ile
                 470                 475                 480

 Ser Phe Cys Leu Asp Ile His Asn Met Ser Val Lys Ala Met Arg
                 485                 490                 495

 Phe Pro Pro Lys Ser Tyr Asn Lys Asp Leu Glu Ser Ala Glu Glu
                 500                 505                 510

 Arg Arg Glu Arg Glu Gln Gln Asp Leu Glu Phe Ala Lys Glu Met
                 515                 520                 525

 Ala Glu Asp Asp Asp Asp Ser Phe Pro
                 530

<210> 313
<211> 2225
<212> DNA
<213> Homo sapien

<400> 313
 cgacatggcg cgcgagctgc gggcgctgct gctgtggggc cgccgcctgc 50

 ggcctttgct gcgggcgccg gcgctggcgg ccgtgccggg aggaaaacca 100

 attctgtgtc ctcggaggac cacagcccag ttgggcccca ggcgaaaccc 150

 agcctggagc ttgcaggcag gacgactgtt cagcacgcag accgccgagg 200

 acaaggagga acccctgcac tcgattatca gcagcacaga gagcgtgcag 250

 ggttccactt ccaaacatga gttccaggcc gagacaaaga agcttttgga 300

 cattgttgcc cggtccctgt actcagaaaa agaggtgttt atacgggagc 350

 tgatctccaa tgccagcgat gccttggaaa aactgcgtca caaactggtg 400

 tctgacggcc aagcactgcc agaaatggag attcacttgc agaccaatgc 450

 cgagaaaggc accatcacca tccaggatac tggtatcggg atgacacagg 500

 aagagctggt gtccaacctg gggacgattg ccagatcggg gtcaaaggcc 550

 ttcctggatg ctctgcagaa ccaggctgag gccagcagca agatcatcgg 600

 ccagtttgga gtgggtttct actcagcttt catggtggct gacagagtgg 650

 aggtctattc ccgctcggca gccccgggga gcctgggtta ccagtggctt 700

 tcagatggtt ctggagtgtt tgaaatcgcc gaagcttcgg gagttagaac 750

 cgggacaaaa atcatcatcc acctgaaatc cgactgcaag gagttttcca 800

 gcgaggcccg ggtgcgagat gtggtaacga agtacagcaa cttcgtcagc 850

 ttccccttgt acttgaatgg aaggcggatg aacaccttgc aggccatctg 900

 gatgatggac cccaaggatg tcggtgagtg gcaacatgag gagttctacc 950

 gctacgtcgc gcaggctcac gacaagcccc gctacaccct gcactataag 1000

 acggacgcac cgctcaacat ccgcagcatc ttctacgtgc ccgacatgaa 1050

 accgtccatg tttgatgtga gccgggagct gggctccagc gttgcactgt 1100

 acagccgcaa agtcctcatc cagaccaagg ccacggacat cctgcccaag 1150

 tggctgcgct tcatccgagg tgtggtggac agtgaggaca ttcccctgaa 1200

 cctcagccgg gagctgctgc aggagagcgc actcatcagg aaactccggg 1250

 acgttttaca gcagaggctg atcaaattct tcattgacca gagtaaaaaa 1300

 gatgctgaga agtatgcaaa gttttttgaa gattacggcc tgttcatgcg 1350

 ggagggcatt gtgaccgcca ccgagcagga ggtcaaggag gacatagcaa 1400

 agctgctgcg ctacgagtcc tcggcgctgc cctccgggca gctaaccagc 1450

 ctctcagaat acgccagccg catgcgggcc ggcacccgca acatctacta 1500

 cctgtgcgcc cccaaccgtc acctggcaga gcactcaccc tactatgagg 1550

 ccatgaagaa gaaagacaca gaggttctct tctgctttga gcagtttgat 1600

 gagctcaccc tgctgcacct tcgtgagttt gacaagaaga agctgatctc 1650

 tgtggagacg gacatagtcg tggatcacta caaggaggag aagtttgagg 1700

 acaggtcccc agccgccgag tgcctatcag agaaggagac ggaggagctc 1750

 atggcctgga tgagaaatgt gctggggtcg cgtgtcacca acgtgaaggt 1800

 gaccctccga ctggacaccc accctgccat ggtcaccgtg ctggagatgg 1850

 gggctgcccg ccacttcctg cgcatgcagc agctggccaa gacccaggag 1900

 gagcgcgcac agctcctgca gcccacgctg gagatcaacc ccaggcacgc 1950

 gctcatcaag aagctgaatc agctgcgcgc aagcgagcct ggcctggctc 2000

 agctgctggt ggatcagata tacgagaacg ccatgattgc tgctggactt 2050

 gttgacgacc ctagggccat ggtgggccgc ttgaatgagc tgcttgtcaa 2100

 ggccctggag cgacactgac agccaggggg ccagaaggac tgacaccaca 2150

 gatgacagcc ccacctcctt gagctttatt tacctaaatt taaaggtatt 2200

 tcttaacccg aaaaaaaaaa aaaaa 2225

<210> 314
<211> 704
<212> PRT
<213> Homo sapien

<400> 314
 Met Ala Arg Glu Leu Arg Ala Leu Leu Leu Trp Gly Arg Arg Leu
   1               5                  10                  15

 Arg Pro Leu Leu Arg Ala Pro Ala Leu Ala Ala Val Pro Gly Gly
                  20                  25                  30

 Lys Pro Ile Leu Cys Pro Arg Arg Thr Thr Ala Gln Leu Gly Pro
                  35                  40                  45

 Arg Arg Asn Pro Ala Trp Ser Leu Gln Ala Gly Arg Leu Phe Ser
                  50                  55                  60

 Thr Gln Thr Ala Glu Asp Lys Glu Glu Pro Leu His Ser Ile Ile
                  65                  70                  75

 Ser Ser Thr Glu Ser Val Gln Gly Ser Thr Ser Lys His Glu Phe
                  80                  85                  90

 Gln Ala Glu Thr Lys Lys Leu Leu Asp Ile Val Ala Arg Ser Leu
                  95                 100                 105

 Tyr Ser Glu Lys Glu Val Phe Ile Arg Glu Leu Ile Ser Asn Ala
                 110                 115                 120

 Ser Asp Ala Leu Glu Lys Leu Arg His Lys Leu Val Ser Asp Gly
                 125                 130                 135

 Gln Ala Leu Pro Glu Met Glu Ile His Leu Gln Thr Asn Ala Glu
                 140                 145                 150

 Lys Gly Thr Ile Thr Ile Gln Asp Thr Gly Ile Gly Met Thr Gln
                 155                 160                 165

 Glu Glu Leu Val Ser Asn Leu Gly Thr Ile Ala Arg Ser Gly Ser
                 170                 175                 180

 Lys Ala Phe Leu Asp Ala Leu Gln Asn Gln Ala Glu Ala Ser Ser
                 185                 190                 195

 Lys Ile Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala Phe Met
                 200                 205                 210

 Val Ala Asp Arg Val Glu Val Tyr Ser Arg Ser Ala Ala Pro Gly
                 215                 220                 225

 Ser Leu Gly Tyr Gln Trp Leu Ser Asp Gly Ser Gly Val Phe Glu
                 230                 235                 240

 Ile Ala Glu Ala Ser Gly Val Arg Thr Gly Thr Lys Ile Ile Ile
                 245                 250                 255

 His Leu Lys Ser Asp Cys Lys Glu Phe Ser Ser Glu Ala Arg Val
                 260                 265                 270

 Arg Asp Val Val Thr Lys Tyr Ser Asn Phe Val Ser Phe Pro Leu
                 275                 280                 285

 Tyr Leu Asn Gly Arg Arg Met Asn Thr Leu Gln Ala Ile Trp Met
                 290                 295                 300

 Met Asp Pro Lys Asp Val Gly Glu Trp Gln His Glu Glu Phe Tyr
                 305                 310                 315

 Arg Tyr Val Ala Gln Ala His Asp Lys Pro Arg Tyr Thr Leu His
                 320                 325                 330

 Tyr Lys Thr Asp Ala Pro Leu Asn Ile Arg Ser Ile Phe Tyr Val
                 335                 340                 345

 Pro Asp Met Lys Pro Ser Met Phe Asp Val Ser Arg Glu Leu Gly
                 350                 355                 360

 Ser Ser Val Ala Leu Tyr Ser Arg Lys Val Leu Ile Gln Thr Lys
                 365                 370                 375

 Ala Thr Asp Ile Leu Pro Lys Trp Leu Arg Phe Ile Arg Gly Val
                 380                 385                 390

 Val Asp Ser Glu Asp Ile Pro Leu Asn Leu Ser Arg Glu Leu Leu
                 395                 400                 405

 Gln Glu Ser Ala Leu Ile Arg Lys Leu Arg Asp Val Leu Gln Gln
                 410                 415                 420

 Arg Leu Ile Lys Phe Phe Ile Asp Gln Ser Lys Lys Asp Ala Glu
                 425                 430                 435

 Lys Tyr Ala Lys Phe Phe Glu Asp Tyr Gly Leu Phe Met Arg Glu
                 440                 445                 450

 Gly Ile Val Thr Ala Thr Glu Gln Glu Val Lys Glu Asp Ile Ala
                 455                 460                 465

 Lys Leu Leu Arg Tyr Glu Ser Ser Ala Leu Pro Ser Gly Gln Leu
                 470                 475                 480

 Thr Ser Leu Ser Glu Tyr Ala Ser Arg Met Arg Ala Gly Thr Arg
                 485                 490                 495

 Asn Ile Tyr Tyr Leu Cys Ala Pro Asn Arg His Leu Ala Glu His
                 500                 505                 510

 Ser Pro Tyr Tyr Glu Ala Met Lys Lys Lys Asp Thr Glu Val Leu
                 515                 520                 525

 Phe Cys Phe Glu Gln Phe Asp Glu Leu Thr Leu Leu His Leu Arg
                 530                 535                 540

 Glu Phe Asp Lys Lys Lys Leu Ile Ser Val Glu Thr Asp Ile Val
                 545                 550                 555

 Val Asp His Tyr Lys Glu Glu Lys Phe Glu Asp Arg Ser Pro Ala
                 560                 565                 570

 Ala Glu Cys Leu Ser Glu Lys Glu Thr Glu Glu Leu Met Ala Trp
                 575                 580                 585

 Met Arg Asn Val Leu Gly Ser Arg Val Thr Asn Val Lys Val Thr
                 590                 595                 600

 Leu Arg Leu Asp Thr His Pro Ala Met Val Thr Val Leu Glu Met
                 605                 610                 615

 Gly Ala Ala Arg His Phe Leu Arg Met Gln Gln Leu Ala Lys Thr
                 620                 625                 630

 Gln Glu Glu Arg Ala Gln Leu Leu Gln Pro Thr Leu Glu Ile Asn
                 635                 640                 645

 Pro Arg His Ala Leu Ile Lys Lys Leu Asn Gln Leu Arg Ala Ser
                 650                 655                 660

 Glu Pro Gly Leu Ala Gln Leu Leu Val Asp Gln Ile Tyr Glu Asn
                 665                 670                 675

 Ala Met Ile Ala Ala Gly Leu Val Asp Asp Pro Arg Ala Met Val
                 680                 685                 690

 Gly Arg Leu Asn Glu Leu Leu Val Lys Ala Leu Glu Arg His
                 695                 700

<210> 315
<211> 1968
<212> DNA
<213> Homo sapien

<400> 315
 gaggaggagg aggagatgac tggggagcgg gagctcgaga atactgccca 50

 gttactctag cgcgccaggc cgaaccgcag cttcttggct taggtacttc 100

 tactcacagc ggccgattcc gaggccaact ccagcaatgg cttttgcaaa 150

 tctgcggaaa gtgctcatca gtgacagcct ggacccttgc tgccggaaga 200

 tcttgcaaga tggagggctg caggtggtgg aaaagcagaa ccttagcaaa 250

 gaggagctga tagcggagct gcaggactgt gaaggcctta ttgttcgctc 300

 tgccaccaag gtgaccgctg atgtcatcaa cgcagctgag aaactccagg 350

 tggtgggcag ggctggcaca ggtgtggaca atgtggatct ggaggccgca 400

 acaaggaagg gcatcttggt tatgaacacc cccaatggga acagcctcag 450

 tgccgcagaa ctcacttgtg gaatgatcat gtgcctggcc aggcagattc 500

 cccaggcgac ggcttcgatg aaggacggca aatgggagcg gaagaagttc 550

 atgggaacag agctgaatgg aaagaccctg ggaattcttg gcctgggcag 600

 gattgggaga gaggtagcta cccggatgca gtcctttggg atgaagacta 650

 tagggtatga ccccatcatt tccccagagg tctcggcctc ctttggtgtt 700

 cagcagctgc ccctggagga gatctggcct ctctgtgatt tcatcactgt 750

 gcacactcct ctcctgccct ccacgacagg cttgctgaat gacaacacct 800

 ttgcccagtg caagaagggg gtgcgtgtgg tgaactgtgc ccgtggaggg 850

 atcgtggacg aaggcgccct gctccgggcc ctgcagtctg gccagtgtgc 900

 cggggctgca ctggacgtgt ttacggaaga gccgccacgg gaccgggcct 950

 tggtggacca tgagaatgtc atcagctgtc cccacctggg tgccagcacc 1000

 aaggaggctc agagccgctg tggggaggaa attgctgttc agttcgtgga 1050

 catggtgaag gggaaatctc tcacgggggt tgtgaatgcc caggccctta 1100

 ccagtgcctt ctctccacac accaagcctt ggattggtct ggcagaagct 1150

 ctggggacac tgatgcgagc ctgggctggg tcccccaaag ggaccatcca 1200

 ggtgataaca cagggaacat ccctgaagaa tgctgggaac tgcctaagcc 1250

 ccgcagtcat tgtcggcctc ctgaaagagg cttccaagca ggcggatgtg 1300

 aacttggtga acgctaagct gctggtgaaa gaggctggcc tcaatgtcac 1350

 cacctcccac agccctgctg caccagggga gcaaggcttc ggggaatgcc 1400

 tcctggccgt ggccctggca ggcgcccctt accaggctgt gggcttggtc 1450

 caaggcacta cacctgtact gcaggggctc aatggagctg tcttcaggcc 1500

 agaagtgcct ctccgcaggg acctgcccct gctcctattc cggactcaga 1550

 cctctgaccc tgcaatgctg cctaccatga ttggcctcct ggcagaggca 1600

 ggcgtgcggc tgctgtccta ccagacttca ctggtgtcag atggggagac 1650

 ctggcacgtc atgggcatct cctccttgct gcccagcctg gaagcgtgga 1700

 agcagcatgt gactgaagcc ttccagttcc acttctaacc ttggagctca 1750

 ctggtccctg cctctggggc ttttctgaag aaacccaccc actgtgatca 1800

 atagggagag aaaatccaca ttcttgggct gaacgcgggc ctctgacact 1850

 gcttacactg cactctgacc ctgtagtaca gcaataaccg tctaataaag 1900

 agcctacccc caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1950

 aaaaaaaaaa aaaaaaaa 1968

<210> 316
<211> 533
<212> PRT
<213> Homo sapien

<400> 316
 Met Ala Phe Ala Asn Leu Arg Lys Val Leu Ile Ser Asp Ser Leu
   1               5                  10                  15

 Asp Pro Cys Cys Arg Lys Ile Leu Gln Asp Gly Gly Leu Gln Val
                  20                  25                  30

 Val Glu Lys Gln Asn Leu Ser Lys Glu Glu Leu Ile Ala Glu Leu
                  35                  40                  45

 Gln Asp Cys Glu Gly Leu Ile Val Arg Ser Ala Thr Lys Val Thr
                  50                  55                  60

 Ala Asp Val Ile Asn Ala Ala Glu Lys Leu Gln Val Val Gly Arg
                  65                  70                  75

 Ala Gly Thr Gly Val Asp Asn Val Asp Leu Glu Ala Ala Thr Arg
                  80                  85                  90

 Lys Gly Ile Leu Val Met Asn Thr Pro Asn Gly Asn Ser Leu Ser
                  95                 100                 105

 Ala Ala Glu Leu Thr Cys Gly Met Ile Met Cys Leu Ala Arg Gln
                 110                 115                 120

 Ile Pro Gln Ala Thr Ala Ser Met Lys Asp Gly Lys Trp Glu Arg
                 125                 130                 135

 Lys Lys Phe Met Gly Thr Glu Leu Asn Gly Lys Thr Leu Gly Ile
                 140                 145                 150

 Leu Gly Leu Gly Arg Ile Gly Arg Glu Val Ala Thr Arg Met Gln
                 155                 160                 165

 Ser Phe Gly Met Lys Thr Ile Gly Tyr Asp Pro Ile Ile Ser Pro
                 170                 175                 180

 Glu Val Ser Ala Ser Phe Gly Val Gln Gln Leu Pro Leu Glu Glu
                 185                 190                 195

 Ile Trp Pro Leu Cys Asp Phe Ile Thr Val His Thr Pro Leu Leu
                 200                 205                 210

 Pro Ser Thr Thr Gly Leu Leu Asn Asp Asn Thr Phe Ala Gln Cys
                 215                 220                 225

 Lys Lys Gly Val Arg Val Val Asn Cys Ala Arg Gly Gly Ile Val
                 230                 235                 240

 Asp Glu Gly Ala Leu Leu Arg Ala Leu Gln Ser Gly Gln Cys Ala
                 245                 250                 255

 Gly Ala Ala Leu Asp Val Phe Thr Glu Glu Pro Pro Arg Asp Arg
                 260                 265                 270

 Ala Leu Val Asp His Glu Asn Val Ile Ser Cys Pro His Leu Gly
                 275                 280                 285

 Ala Ser Thr Lys Glu Ala Gln Ser Arg Cys Gly Glu Glu Ile Ala
                 290                 295                 300

 Val Gln Phe Val Asp Met Val Lys Gly Lys Ser Leu Thr Gly Val
                 305                 310                 315

 Val Asn Ala Gln Ala Leu Thr Ser Ala Phe Ser Pro His Thr Lys
                 320                 325                 330

 Pro Trp Ile Gly Leu Ala Glu Ala Leu Gly Thr Leu Met Arg Ala
                 335                 340                 345

 Trp Ala Gly Ser Pro Lys Gly Thr Ile Gln Val Ile Thr Gln Gly
                 350                 355                 360

 Thr Ser Leu Lys Asn Ala Gly Asn Cys Leu Ser Pro Ala Val Ile
                 365                 370                 375

 Val Gly Leu Leu Lys Glu Ala Ser Lys Gln Ala Asp Val Asn Leu
                 380                 385                 390

 Val Asn Ala Lys Leu Leu Val Lys Glu Ala Gly Leu Asn Val Thr
                 395                 400                 405

 Thr Ser His Ser Pro Ala Ala Pro Gly Glu Gln Gly Phe Gly Glu
                 410                 415                 420

 Cys Leu Leu Ala Val Ala Leu Ala Gly Ala Pro Tyr Gln Ala Val
                 425                 430                 435

 Gly Leu Val Gln Gly Thr Thr Pro Val Leu Gln Gly Leu Asn Gly
                 440                 445                 450

 Ala Val Phe Arg Pro Glu Val Pro Leu Arg Arg Asp Leu Pro Leu
                 455                 460                 465

 Leu Leu Phe Arg Thr Gln Thr Ser Asp Pro Ala Met Leu Pro Thr
                 470                 475                 480

 Met Ile Gly Leu Leu Ala Glu Ala Gly Val Arg Leu Leu Ser Tyr
                 485                 490                 495

 Gln Thr Ser Leu Val Ser Asp Gly Glu Thr Trp His Val Met Gly
                 500                 505                 510

 Ile Ser Ser Leu Leu Pro Ser Leu Glu Ala Trp Lys Gln His Val
                 515                 520                 525

 Thr Glu Ala Phe Gln Phe His Phe
                 530

<210> 317
<211> 688
<212> DNA
<213> Homo sapien

<400> 317
 agccccgccc caggcgaggg cgccgcaccc acaccgcgct gcgcagtttt 50

 gttctgctcc agctgttcga aggtgatcca gacgcaagat ggctgtcctc 100

 tctaaggaat atggttttgt gcttctaact ggtgctgcca gctttataat 150

 ggtggcccac ctagccatca atgtttccaa ggcccgcaag aagtacaaag 200

 tggagtatcc tatcatgtac agcacggacc ctgaaaatgg gcacatcttc 250

 aactgcattc agcgagccca ccagaacacg ttggaagtgt atcctccctt 300

 cttatttttt ctagctgttg gaggtgttta ccacccgcgt atagcttctg 350

 gcctgggctt ggcctggatt gttggacgag ttctttatgc ttatggctat 400

 tacacgggag aacccagcaa gcgtagtcga ggagccctgg ggtccatcgc 450

 cctcctgggc ttggtgggca caactgtgtg ctctgctttc cagcatcttg 500

 gttgggttaa aagtggcttg ggcagtggac ccaaatgctg ccattaaaga 550

 attatagggg tttaaaaact ctcattcatt ttaaatgact tacctttatt 600

 tccagttaca ttttttttct aaatataata aaaacttacc tggcatcagc 650

 ctcataccta aaaaaaaaaa aaaaaaaaaa aaaaaaaa 688

<210> 318
<211> 152
<212> PRT
<213> Homo sapien

<400> 318
 Met Ala Val Leu Ser Lys Glu Tyr Gly Phe Val Leu Leu Thr Gly
   1               5                  10                  15

 Ala Ala Ser Phe Ile Met Val Ala His Leu Ala Ile Asn Val Ser
                  20                  25                  30

 Lys Ala Arg Lys Lys Tyr Lys Val Glu Tyr Pro Ile Met Tyr Ser
                  35                  40                  45

 Thr Asp Pro Glu Asn Gly His Ile Phe Asn Cys Ile Gln Arg Ala
                  50                  55                  60

 His Gln Asn Thr Leu Glu Val Tyr Pro Pro Phe Leu Phe Phe Leu
                  65                  70                  75

 Ala Val Gly Gly Val Tyr His Pro Arg Ile Ala Ser Gly Leu Gly
                  80                  85                  90

 Leu Ala Trp Ile Val Gly Arg Val Leu Tyr Ala Tyr Gly Tyr Tyr
                  95                 100                 105

 Thr Gly Glu Pro Ser Lys Arg Ser Arg Gly Ala Leu Gly Ser Ile
                 110                 115                 120

 Ala Leu Leu Gly Leu Val Gly Thr Thr Val Cys Ser Ala Phe Gln
                 125                 130                 135

 His Leu Gly Trp Val Lys Ser Gly Leu Gly Ser Gly Pro Lys Cys
                 140                 145                 150

 Cys His


<210> 319
<211> 425
<212> DNA
<213> Rattus norvegicus

<400> 319
 gcggtttctt tctttccgcg ccgatagcgc tcacgcaagc atggttaacg 50

 tccctaaaac ccgccggact ttctgtaaga agtgtggcaa gcaccaaccc 100

 cataaagtga cacagtacaa gaagggcaag gattctctgt acgcccaggg 150

 aaagcggcgt tatgacagga agcagagtgg ctatggtggg caaactaagc 200

 cgattttccg gaaaaaggct aaaactacaa agaagattgt gctaaggctt 250

 gagtgcgttg agcccaactg cagatctaag agaatgctgg ctattaaaag 300

 atgcaagcat tttgaactgg gaggagataa gaagagaaag ggccaagtga 350

 tccagttcta agtgtcatct tttattatga agacaataaa atcttgagtt 400

 tatgttcaaa aaaaaaaaaa aaaaa 425

<210> 320
<211> 106
<212> PRT
<213> Rattus norvegicus

<400> 320
 Met Val Asn Val Pro Lys Thr Arg Arg Thr Phe Cys Lys Lys Cys
   1               5                  10                  15

 Gly Lys His Gln Pro His Lys Val Thr Gln Tyr Lys Lys Gly Lys
                  20                  25                  30

 Asp Ser Leu Tyr Ala Gln Gly Lys Arg Arg Tyr Asp Arg Lys Gln
                  35                  40                  45

 Ser Gly Tyr Gly Gly Gln Thr Lys Pro Ile Phe Arg Lys Lys Ala
                  50                  55                  60

 Lys Thr Thr Lys Lys Ile Val Leu Arg Leu Glu Cys Val Glu Pro
                  65                  70                  75

 Asn Cys Arg Ser Lys Arg Met Leu Ala Ile Lys Arg Cys Lys His
                  80                  85                  90

 Phe Glu Leu Gly Gly Asp Lys Lys Arg Lys Gly Gln Val Ile Gln
                  95                 100                 105

 Phe


<210> 321
<211> 2428
<212> DNA
<213> Homo sapien

<400> 321
 cgtccagttt gagtctaggt tggagttgga accgtggaga tgcggaagga 50

 aaccccaccc cccctagtgc ccccggcggc ccgggagtgg aatcttcccc 100

 caaatgcgcc cgcctgcatg gaacggcagt tggaggctgc gcggtaccgg 150

 tccgatgggg cgcttctcct cggggcctcc agcctgagtg ggcgctgctg 200

 ggccggctcc ctctggcttt ttaaggaccc ctgtgccgcc cccaacgaag 250

 gcttctgctc cgccggagtc caaacggagg ctggagtggc tgacctcact 300

 tgggttgggg agagaggtat tctagtggcc tccgattcag gtgctgttga 350

 attgtgggaa ctagatgaga atgagacact tattgtcagc aagttctgca 400

 agtatgagca tgatgacatt gtgtctacag tcagtgtctt gagctctggc 450

 acacaagctg tcagtggtag caaagacatc tgcatcaagg tttgggacct 500

 tgctcagcag gtggtactga gttcataccg agctcatgct gctcaggtca 550

 cttgtgttgc tgcctctcct cacaaggact ctgtgtttct ttcatgcagc 600

 gaggacaata gaattttact ctgggatacc cgctgtccca agccagcatc 650

 acagattggc tgcagtgcgc ctggctacct tcctacctcg ctggcttggc 700

 atcctcagca aagtgaagtc tttgtctttg gtgatgagaa tgggacagtc 750

 tcccttgtgg acaccaagag tacaagctgt gtcctgagct cagctgtaca 800

 ctcccagtgt gtcactgggc tggtgttctc cccacacagt gttcccttcc 850

 tggcctctct cagtgaagac tgctcacttg ctgtgctgga ctcaagcctt 900

 tctgagttgt ttagaagcca agcccacaga gactttgtga gagatgcgac 950

 ttggtccccg ctcaatcact ccctgcttac cacagtgggc tgggaccatc 1000

 aggtcgtcca ccacgttgtg cccacagaac ctctcccagc ccctggacct 1050

 gcaagtgtta ctgagtagat tggatttaag acaaaaagca agtcccccat 1100

 gagtgtccac ttctttgccc tgccctctca gcttgtgaga caacacagga 1150

 gccttctata gtatgttgat atgctagatc tgtgccgtta ataggcatcg 1200

 tctctcagcc tgagggaggc tggattctgg gttcctgtag tcacagggag 1250

 gaaaagcttt cttaaaaatg gacatgtatg tgcgtgtgag tgtgtgtgta 1300

 gatttatagt ttttggtagt ggcaggaata aaaaaaatcc atcctacatc 1350

 ttccctaagc actgcctctc tctcaccccc caaaacaagt tgacgaaagg 1400

 gttttatgta gctgtctatg aggaattggc cgtgtctggg tgggttatgg 1450

 gatgtgggca tccctgggtt cttggaagca gctcttatgc tactcataga 1500

 gatgggattg actttatttt tttatagtgc ttaattcacc attatgagaa 1550

 atgcttccag tcacaaaaat gcagcccagc tcactctgag gaagaagcag 1600

 gacttggtac ggttttacac aactccttac cattaaactg aatcagaaat 1650

 ccattttctg gctgaataaa aagtttggct tgcctgtgta atgcccactc 1700

 ccttccccct ggctccctag tgatgggaca tatatgagag agaagtgttt 1750

 ttctatcata gacaccatag gggaaagttt ggggatgaag gagagcttaa 1800

 aggtgtttca attaagttag aaaactgaca caggctgttg agaattcttt 1850

 gccacttttc ccaccccaaa acagcatggg gcctgacatc ttctgccctg 1900

 gtcccctttc tcttgatgtg gaaagtctga atgcagtatt tatagacttc 1950

 taaggtttta aaatccagta tcaagaagaa aatcagaaat actggttggt 2000

 gaaataaaga gtttaggcat tgttggcctg tcttttttga agcatgtgtg 2050

 ttatgtgtag ttagatatat ttcacttatg tgagtcatca tggtgttggt 2100

 cttgtagccc attatttttc ctgtgcttcc ccagcttccc aaagtagcta 2150

 gttagaactt aaggtaaata tttattcttg ggttggtgga gtggatattg 2200

 ccagttagga gtcatggatc aattactgat tatattgaaa gtaaatataa 2250

 tcaattatgt acttttgagc tttgcaggtt caatttaggt aaaaatcaca 2300

 ttatgaaact gggaaagtct gaaggaatat gggcaaaata tttctcagta 2350

 aagcttccat gcttcaccct tgacatgatt acccttgagt aaaacatggg 2400

 aatttgtaaa aaaaaaaaaa aaaaaaaa 2428

<210> 322
<211> 342
<212> PRT
<213> Homo sapien

<400> 322
 Met Arg Lys Glu Thr Pro Pro Pro Leu Val Pro Pro Ala Ala Arg
   1               5                  10                  15

 Glu Trp Asn Leu Pro Pro Asn Ala Pro Ala Cys Met Glu Arg Gln
                  20                  25                  30

 Leu Glu Ala Ala Arg Tyr Arg Ser Asp Gly Ala Leu Leu Leu Gly
                  35                  40                  45

 Ala Ser Ser Leu Ser Gly Arg Cys Trp Ala Gly Ser Leu Trp Leu
                  50                  55                  60

 Phe Lys Asp Pro Cys Ala Ala Pro Asn Glu Gly Phe Cys Ser Ala
                  65                  70                  75

 Gly Val Gln Thr Glu Ala Gly Val Ala Asp Leu Thr Trp Val Gly
                  80                  85                  90

 Glu Arg Gly Ile Leu Val Ala Ser Asp Ser Gly Ala Val Glu Leu
                  95                 100                 105

 Trp Glu Leu Asp Glu Asn Glu Thr Leu Ile Val Ser Lys Phe Cys
                 110                 115                 120

 Lys Tyr Glu His Asp Asp Ile Val Ser Thr Val Ser Val Leu Ser
                 125                 130                 135

 Ser Gly Thr Gln Ala Val Ser Gly Ser Lys Asp Ile Cys Ile Lys
                 140                 145                 150

 Val Trp Asp Leu Ala Gln Gln Val Val Leu Ser Ser Tyr Arg Ala
                 155                 160                 165

 His Ala Ala Gln Val Thr Cys Val Ala Ala Ser Pro His Lys Asp
                 170                 175                 180

 Ser Val Phe Leu Ser Cys Ser Glu Asp Asn Arg Ile Leu Leu Trp
                 185                 190                 195

 Asp Thr Arg Cys Pro Lys Pro Ala Ser Gln Ile Gly Cys Ser Ala
                 200                 205                 210

 Pro Gly Tyr Leu Pro Thr Ser Leu Ala Trp His Pro Gln Gln Ser
                 215                 220                 225

 Glu Val Phe Val Phe Gly Asp Glu Asn Gly Thr Val Ser Leu Val
                 230                 235                 240

 Asp Thr Lys Ser Thr Ser Cys Val Leu Ser Ser Ala Val His Ser
                 245                 250                 255

 Gln Cys Val Thr Gly Leu Val Phe Ser Pro His Ser Val Pro Phe
                 260                 265                 270

 Leu Ala Ser Leu Ser Glu Asp Cys Ser Leu Ala Val Leu Asp Ser
                 275                 280                 285

 Ser Leu Ser Glu Leu Phe Arg Ser Gln Ala His Arg Asp Phe Val
                 290                 295                 300

 Arg Asp Ala Thr Trp Ser Pro Leu Asn His Ser Leu Leu Thr Thr
                 305                 310                 315

 Val Gly Trp Asp His Gln Val Val His His Val Val Pro Thr Glu
                 320                 325                 330

 Pro Leu Pro Ala Pro Gly Pro Ala Ser Val Thr Glu
                 335                 340

<210> 323
<211> 2279
<212> DNA
<213> Homo sapien

<400> 323
 tgcctgctga gggtggagac ccacgagccg aggcctcctg cagtgttctg 50

 cacagcaaac cgcacgctat ggctgacagc cgggatcccg ccagcgacca 100

 gatgcagcac tggaaggagc agcgggccgc gcagaaagct gatgtcctga 150

 ccactggagc tggtaaccca gtaggagaca aacttaatgt tattacagta 200

 gggccccgtg ggccccttct tgttcaggat gtggttttca ctgatgaaat 250

 ggctcatttt gaccgagaga gaattcctga gagagttgtg catgctaaag 300

 gagcaggggc ctttggctac tttgaggtca cacatgacat taccaaatac 350

 tccaaggcaa aggtatttga gcatattgga aagaagactc ccatcgcagt 400

 tcggttctcc actgttgctg gagaatcggg ttcagctgac acagttcggg 450

 accctcgtgg gtttgcagtg aaattttaca cagaagatgg taactgggat 500

 ctcgttggaa ataacacccc cattttcttc atcagggatc ccatattgtt 550

 tccatctttt atccacagcc aaaagagaaa tcctcagaca catctgaagg 600

 atccggacat ggtctgggac ttctggagcc tacgtcctga gtctctgcat 650

 caggtttctt tcttgttcag tgatcggggg attccagatg gacatcgcca 700

 catgaatgga tatggatcac atactttcaa gctggttaat gcaaatgggg 750

 aggcagttta ttgcaaattc cattataaga ctgaccaggg catcaaaaac 800

 ctttctgttg aagatgcggc gagactttcc caggaagatc ctgactatgg 850

 catccgggat ctttttaacg ccattgccac aggaaagtac ccctcctgga 900

 ctttttacat ccaggtcatg acatttaatc aggcagaaac ttttccattt 950

 aatccattcg atctcaccaa ggtttggcct cacaaggact accctctcat 1000

 cccagttggt aaactggtct taaaccggaa tccagttaat tactttgctg 1050

 aggttgaaca gatagccttc gacccaagca acatgccacc tggcattgag 1100

 gccagtcctg acaaaatgct tcagggccgc ctttttgcct atcctgacac 1150

 tcaccgccat cgcctgggac ccaattatct tcatatacct gtgaactgtc 1200

 cctaccgtgc tcgagtggcc aactaccagc gtgatggccc gatgtgcatg 1250

 caggacaatc agggtggtgc tccaaattac taccccaaca gctttggtgc 1300

 tccggaacaa cagccttctg ccctggagca cagcatccaa tattctggag 1350

 aagtgcggag attcaacact gccaatgatg ataacgttac tcaggtgcgg 1400

 gcattctatg tgaacgtgct gaatgaggaa cagaggaaac gtctgtgtga 1450

 gaacattgcc ggccacctga aggatgcaca aattttcatc cagaagaaag 1500

 cggtcaagaa cttcactgag gtccaccctg actacgggag ccacatccag 1550

 gctcttctgg acaagtacaa tgctgagaag cctaagaatg cgattcacac 1600

 ctttgtgcag tccggatctc acttggcggc aagggagaag gcaaatctgt 1650

 gaggccgggg ccctgcacct gtgcagcgaa gcttagcgtt catccgtgta 1700

 acccgctcat cactggatga agattctcct gtgctagatg tgcaaatgca 1750

 agctagtggc ttcaaaatag agaatcccac tttctatagc agattgtgta 1800

 acaattttaa tgctatttcc ccaggggaaa atgaaggtta ggatttaaca 1850

 gtcatttaaa aaaaaaattt gttttgacgg atgattggat tattcattta 1900

 aaatgattag aaggcaagtt tctagctaga aatatgattt tatttgacaa 1950

 aatttgttga aattatgtat gtttacatat cacctcatgg cctattatat 2000

 taaaatatgg ctataaatat ataaaaagaa aagataaaga tgatctactc 2050

 agaaattttt atttttctaa ggttctcata ggaaaagtac atttaataca 2100

 gcagtgtcat cagaagataa cttgagcacc gtcatggctt aatgtttatt 2150

 cctgataata attgatcaaa ttcatttttt tcactggagt tacattaatg 2200

 ttaattcagc actgatttca caacagatca atttgtaatt gcttacattt 2250

 ttacaataaa taatctgtac gtaagaaca 2279

<210> 324
<211> 527
<212> PRT
<213> Homo sapien

<400> 324
 Met Ala Asp Ser Arg Asp Pro Ala Ser Asp Gln Met Gln His Trp
   1               5                  10                  15

 Lys Glu Gln Arg Ala Ala Gln Lys Ala Asp Val Leu Thr Thr Gly
                  20                  25                  30

 Ala Gly Asn Pro Val Gly Asp Lys Leu Asn Val Ile Thr Val Gly
                  35                  40                  45

 Pro Arg Gly Pro Leu Leu Val Gln Asp Val Val Phe Thr Asp Glu
                  50                  55                  60

 Met Ala His Phe Asp Arg Glu Arg Ile Pro Glu Arg Val Val His
                  65                  70                  75

 Ala Lys Gly Ala Gly Ala Phe Gly Tyr Phe Glu Val Thr His Asp
                  80                  85                  90

 Ile Thr Lys Tyr Ser Lys Ala Lys Val Phe Glu His Ile Gly Lys
                  95                 100                 105

 Lys Thr Pro Ile Ala Val Arg Phe Ser Thr Val Ala Gly Glu Ser
                 110                 115                 120

 Gly Ser Ala Asp Thr Val Arg Asp Pro Arg Gly Phe Ala Val Lys
                 125                 130                 135

 Phe Tyr Thr Glu Asp Gly Asn Trp Asp Leu Val Gly Asn Asn Thr
                 140                 145                 150

 Pro Ile Phe Phe Ile Arg Asp Pro Ile Leu Phe Pro Ser Phe Ile
                 155                 160                 165

 His Ser Gln Lys Arg Asn Pro Gln Thr His Leu Lys Asp Pro Asp
                 170                 175                 180

 Met Val Trp Asp Phe Trp Ser Leu Arg Pro Glu Ser Leu His Gln
                 185                 190                 195

 Val Ser Phe Leu Phe Ser Asp Arg Gly Ile Pro Asp Gly His Arg
                 200                 205                 210

 His Met Asn Gly Tyr Gly Ser His Thr Phe Lys Leu Val Asn Ala
                 215                 220                 225

 Asn Gly Glu Ala Val Tyr Cys Lys Phe His Tyr Lys Thr Asp Gln
                 230                 235                 240

 Gly Ile Lys Asn Leu Ser Val Glu Asp Ala Ala Arg Leu Ser Gln
                 245                 250                 255

 Glu Asp Pro Asp Tyr Gly Ile Arg Asp Leu Phe Asn Ala Ile Ala
                 260                 265                 270

 Thr Gly Lys Tyr Pro Ser Trp Thr Phe Tyr Ile Gln Val Met Thr
                 275                 280                 285

 Phe Asn Gln Ala Glu Thr Phe Pro Phe Asn Pro Phe Asp Leu Thr
                 290                 295                 300

 Lys Val Trp Pro His Lys Asp Tyr Pro Leu Ile Pro Val Gly Lys
                 305                 310                 315

 Leu Val Leu Asn Arg Asn Pro Val Asn Tyr Phe Ala Glu Val Glu
                 320                 325                 330

 Gln Ile Ala Phe Asp Pro Ser Asn Met Pro Pro Gly Ile Glu Ala
                 335                 340                 345

 Ser Pro Asp Lys Met Leu Gln Gly Arg Leu Phe Ala Tyr Pro Asp
                 350                 355                 360

 Thr His Arg His Arg Leu Gly Pro Asn Tyr Leu His Ile Pro Val
                 365                 370                 375

 Asn Cys Pro Tyr Arg Ala Arg Val Ala Asn Tyr Gln Arg Asp Gly
                 380                 385                 390

 Pro Met Cys Met Gln Asp Asn Gln Gly Gly Ala Pro Asn Tyr Tyr
                 395                 400                 405

 Pro Asn Ser Phe Gly Ala Pro Glu Gln Gln Pro Ser Ala Leu Glu
                 410                 415                 420

 His Ser Ile Gln Tyr Ser Gly Glu Val Arg Arg Phe Asn Thr Ala
                 425                 430                 435

 Asn Asp Asp Asn Val Thr Gln Val Arg Ala Phe Tyr Val Asn Val
                 440                 445                 450

 Leu Asn Glu Glu Gln Arg Lys Arg Leu Cys Glu Asn Ile Ala Gly
                 455                 460                 465

 His Leu Lys Asp Ala Gln Ile Phe Ile Gln Lys Lys Ala Val Lys
                 470                 475                 480

 Asn Phe Thr Glu Val His Pro Asp Tyr Gly Ser His Ile Gln Ala
                 485                 490                 495

 Leu Leu Asp Lys Tyr Asn Ala Glu Lys Pro Lys Asn Ala Ile His
                 500                 505                 510

 Thr Phe Val Gln Ser Gly Ser His Leu Ala Ala Arg Glu Lys Ala
                 515                 520                 525

 Asn Leu


<210> 325
<211> 10558
<212> DNA
<213> Homo sapien

<400> 325
 cagtttggag ctcagtcttc caccaaaggc cgttcagttc tcctgggctc 50

 cagcctcctg caaggactgc aagagttttc ctccgcagct ctgagtctcc 100

 acttttttgg tggagaaagg ctgcaaaaag aaaaagagac gcagtgagtg 150

 ggaaaagtat gcatcctatt caaacctaat tgaatcgagg agcccaggga 200

 cacacgcctt caggtttgct caggggttca tatttggtgc ttagacaaat 250

 tcaaaatgag gaaacatcgg cacttgccct tagtggccgt cttttgcctc 300

 tttctctcag gctttcctac aactcatgcc cagcagcagc aagcagatgt 350

 caaaaatggt gcggctgctg atataatatt tctagtggat tcctcttgga 400

 ccattggaga ggaacatttc caacttgttc gagagtttct atatgatgtt 450

 gtaaaatcct tagctgtggg agaaaatgat ttccattttg ctctggtcca 500

 gttcaacgga aacccacata ccgagttcct gttaaatacg tatcgtacta 550

 aacaagaagt cctttctcat atttccaaca tgtcttatat tgggggaacc 600

 aatcagactg gaaaaggatt agaatacata atgcaaagcc acctcaccaa 650

 ggctgctgga agccgggccg gtgacggagt ccctcaggtt atcgtagtgt 700

 taactgatgg acactcgaag gatggccttg ctctgccctc agcggaactt 750

 aagtctgctg atgttaacgt gtttgcaatt ggagttgagg atgcagatga 800

 aggagcgtta aaagaaatag caagtgaacc gctcaatatg catatgttca 850

 acctagagaa ttttacctca cttcatgaca tagtaggaaa cttagtgtcc 900

 tgtgtgcatt catccgtgag tccagaaagg gctggggaca cggaaaccct 950

 taaagacatc acagcacaag actctgctga cattattttc cttattgatg 1000

 gatcaaacaa caccggaagt gtcaatttcg cagtcattct cgacttcctt 1050

 gtaaatctcc ttgagaaact cccaattgga actcagcaga tccgagtggg 1100

 ggtggtccag tttagcgatg agcccagaac catgttttcc ttggacacct 1150

 actccaccaa ggcccaggtt ctgggtgcag tgaaagccct cgggtttgct 1200

 ggtggggagt tggccaatat cggcctcgcc cttgatttcg tggtggagaa 1250

 ccacttcacc cgggcagggg gcagccgcgt ggaggaaggg gttccccagg 1300

 tgctggtcct cataagtgcc gggccttcta gtgacgagat tcgctacggg 1350

 gtggtagcac tgaagcaggc tagcgtgttc tcattcggcc ttggagccca 1400

 ggccgcctcc agggcagagc ttcagcacat agctaccgat gacaacttgg 1450

 tgtttactgt cccggaattc cgtagctttg gggacctcca ggagaaatta 1500

 ctgccgtaca ttgttggcgt ggcccaaagg cacattgtct tgaaaccgcc 1550

 aaccattgtc acacaagtca ttgaagtcaa caagagagac atagtcttcc 1600

 tggtggatgg ctcatctgca ctgggactgg ccaacttcaa tgccatccga 1650

 gacttcattg ctaaagtcat ccagaggctg gaaatcggac aggatcttat 1700

 ccaggtggca gtggcccagt atgcagacac tgtgaggcct gaattttatt 1750

 tcaataccca tccaacaaaa agggaagtca taaccgctgt gcggaaaatg 1800

 aagcccctgg acggctcggc cctgtacacg ggctctgctc tagactttgt 1850

 tcgtaacaac ctattcacga gttcagccgg ctaccgggct gccgagggga 1900

 ttcctaagct tttggtgctg atcacaggtg gtaagtccct agatgaaatc 1950

 agccagcctg cccaggagct gaagagaagc agcataatgg cctttgccat 2000

 tgggaacaag ggtgccgatc aggctgagct ggaagagatc gctttcgact 2050

 cctccctggt gttcatccca gctgagttcc gagccgcccc attgcaaggc 2100

 atgctgcctg gcttgctggc acctctcagg accctctctg gaacccctga 2150

 agttcactca aacaaaagag atatcatctt tcttttggat ggatcagcca 2200

 acgttggaaa aaccaatttc ccttatgtgc gcgactttgt aatgaaccta 2250

 gttaacagcc ttgatattgg aaatgacaat attcgtgttg gtttagtgca 2300

 atttagtgac actcctgtaa cggagttctc tttaaacaca taccagacca 2350

 agtcagatat ccttggtcat ctgaggcagc tgcagctcca gggaggttcg 2400

 ggcctgaaca caggctcagc cctaagctat gtctatgcca accacttcac 2450

 ggaagctggc ggcagcagga tccgtgaaca cgtgccgcag ctcctgcttc 2500

 tgctcacagc tgggcagtct gaggactcct atttgcaagc tgccaacgcc 2550

 ttgacacgcg cgggcatcct gactttttgt gtgggagcta gccaggcgaa 2600

 taaggcagag cttgagcaga ttgcttttaa cccaagcctg gtgtatctca 2650

 tggatgattt cagctccctg ccagctttgc ctcagcagct gattcagccc 2700

 ctaaccacat atgttagtgg aggtgtggag gaagtaccac tcgctcagcc 2750

 agagagcaag cgagacattc tgttcctctt tgacggctca gccaatcttg 2800

 tgggccagtt ccctgttgtc cgtgactttc tctacaagat tatcgatgag 2850

 ctcaatgtga agccagaggg gacccgaatt gcggtggctc agtacagcga 2900

 tgatgtcaag gtggagtccc gttttgatga gcaccagagt aagcctgaga 2950

 tcctgaatct tgtgaagaga atgaagatca agacgggcaa agccctcaac 3000

 ctgggctacg cgctggacta tgcacagagg tacatttttg tgaagtctgc 3050

 tggcagccgg atcgaggatg gagtgcttca gttcctggtg ctgctggtcg 3100

 caggaaggtc atctgaccgt gtggatgggc cagcaagtaa cctgaagcag 3150

 agtggggttg tgcctttcat cttccaagcc aagaacgcag accctgctga 3200

 gttagagcag atcgtgctgt ctccagcgtt tatcctggct gcagagtcgc 3250

 ttcccaagat tggagatctt catccacaga tagtgaatct cttaaaatca 3300

 gtgcacaacg gagcaccagc accagtttca ggtgaaaagg acgtggtgtt 3350

 tctgcttgat ggctctgagg gcgtcaggag cggcttccct ctgttgaaag 3400

 agtttgtcca gagagtggtg gaaagcctgg atgtgggcca ggaccgggtc 3450

 cgcgtggccg tggtgcagta cagcgaccgg accaggcccg agttctacct 3500

 gaattcatac atgaacaagc aggacgtcgt caacgctgtc cgccagctga 3550

 ccctgctggg agggccgacc cccaacaccg gggccgccct ggagtttgtc 3600

 ctgaggaaca tcctggtcag ctctgcggga agcaggataa cagaaggtgt 3650

 gccccagctg ctgatcgtcc tcacggccga caggtctggg gatgatgtgc 3700

 ggaacccctc cgtggtcgtg aagaggggtg gggctgtgcc cattggcatt 3750

 ggcatcggga acgctgacat cacagagatg cagaccatct ccttcatccc 3800

 ggactttgcc gtggccattc ccacctttcg ccagctgggg accgtccaac 3850

 aggtcatctc tgagagggtg acccagctca cccgcgagga gctgagcagg 3900

 ctgcagccgg tgttgcagcc tctaccgagc ccaggtgttg gtggcaagag 3950

 ggacgtggtc tttctcatcg atgggtccca aagtgccggg cctgagttcc 4000

 agtacgttcg caccctcata gagaggctgg ttgactacct ggacgtgggc 4050

 tttgacacca cccgggtggc tgtcatccag ttcagcgatg accccaaggc 4100

 ggagttcctg ctgaacgccc attccagcaa ggatgaagtg cagaacgcgg 4150

 tgcagcggct gaggcccaag ggagggcggc agatcaacgt gggcaatgcc 4200

 ctggagtacg tgtccaggaa catcttcaag aggcccctgg ggagccgcat 4250

 tgaagagggc gtcccacagt tcctggtcct catctcgtct ggaaagtctg 4300

 acgatgaggt ggtcgtcccg gcggtggagc tcaagcagtt tggcgtggcc 4350

 cctttcacga tcgccaggaa cgcagaccag gaggagctgg tgaagatctc 4400

 gctgagcccc gaatatgtgt tctcggtgag caccttccgg gagctgccca 4450

 gcctggagca gaaactgctg acgcccatca cgaccctgac ctcagagcag 4500

 atccagaagc tcttagccag cactcgctat ccacctccag cagttgagag 4550

 tgatgctgca gacattgtct ttctgatcga cagctctgag ggagttaggc 4600

 cagatggctt tgcacatatt cgagattttg ttagcaggat tgttcgaaga 4650

 ctcaacatcg gccccagtaa agtgagagtt ggggtcgtgc agttcagcaa 4700

 tgatgtcttc ccagaattct atctgaaaac ctacagatcc caggccccgg 4750

 tgctggacgc catacggcgc ctgaggctca gaggggggtc cccactgaac 4800

 actggcaagg ctctcgaatt tgtggcaaga aacctctttg ttaagtctgc 4850

 ggggagtcgc atagaagacg gggtgcccca acacctggtc ctggtcctgg 4900

 gtggaaaatc ccaggacgat gtgtccaggt tcgcccaggt gatccgttcc 4950

 tcgggcattg tgagtttagg ggtaggagac cggaacatcg acagaacaga 5000

 gctgcagacc atcaccaatg accccagact ggtcttcaca gtgcgagagt 5050

 tcagagagct tcccaacata gaagaaagaa tcatgaactc gtttggaccc 5100

 tccgcagcca ctcctgcacc tccaggggtg gacacccctc ctccttcacg 5150

 gccagagaag aagaaagcag acattgtgtt cctgttggat ggttccatca 5200

 acttcaggag ggacagtttc caggaagtgc ttcgttttgt gtctgaaata 5250

 gtggacacag tttatgaaga tggcgactcc atccaagtgg ggcttgtcca 5300

 gtacaactct gaccccactg acgaattctt cctgaaggac ttctctacca 5350

 agaggcagat tattgacgcc atcaacaaag tggtctacaa agggggaaga 5400

 cacgccaaca ctaaggtggg ccttgagcac ctgcgggtaa accactttgt 5450

 gcctgaggca ggcagccgcc tggaccagcg ggtccctcag attgcctttg 5500

 tgatcacggg aggaaagtcg gtggaagatg cacaggatgt gagcctggcc 5550

 ctcacccaga ggggggtcaa agtgtttgct gttggagtga ggaatatcga 5600

 ctcggaggag gttggaaaga tagcgtccaa cagcgccaca gcgttccgcg 5650

 tgggcaacgt ccaggagctg tccgaactga gcgagcaagt tttggaaact 5700

 ttgcatgatg cgatgcatga aaccctttgc cctggtgtaa ctgatgctgc 5750

 caaagcttgt aatctggatg tgattctggg gtttgatggt tctagagacc 5800

 agaatgtttt tgtggcccag aagggcttcg agtccaaggt ggacgccatc 5850

 ttgaacagaa tcagccagat gcacagggtc agctgcagcg gtggccgctc 5900

 gcccaccgtg cgtgtgtcag tggtggccaa cacgccctcg ggcccggtgg 5950

 aggcctttga ctttgacgag taccagccag agatgctcga gaagttccgg 6000

 aacatgcgca gccagcaccc ctacgtcctc acggaggaca ccctgaaggt 6050

 ctacctgaac aagttcagac agtcctcgcc ggacagcgtg aaggtggtca 6100

 ttcattttac tgatggagca gacggagatc tggctgattt acacagagca 6150

 tctgagaacc tccgccaaga aggagtccgt gccttgatcc tggtgggcct 6200

 tgaacgagtg gtcaacttgg agcggctaat gcatctggag tttgggcgag 6250

 ggtttatgta tgacaggccc ctgaggctta acttgctgga cttggattat 6300

 gaactagcgg agcagcttga caacattgcc gagaaagctt gctgtggggt 6350

 tccctgcaag tgctctgggc agaggggaga ccgcgggccc atcggcagca 6400

 tcgggccaaa gggtattcct ggagaagacg gctaccgagg ctatcctggt 6450

 gatgagggtg gacccggtga gcgtggtccg cctggtgtga acggcactca 6500

 aggtttccag ggctgcccgg gccagagagg agtaaagggc tctcggggat 6550

 tcccaggaga gaagggcgaa gtaggagaaa ttggactgga tggtctggat 6600

 ggtgaagatg gagacaaagg attgcctggt tcttctggag agaaagggaa 6650

 tcctggaaga aggggtgata aaggacctcg aggagagaaa ggagaaagag 6700

 gagatgttgg gattcgaggg gacccgggta acccaggaca agacagccag 6750

 gagagaggac ccaaaggaga aaccggtgac ctcggcccca tgggtgtccc 6800

 agggagagat ggagtacctg gaggacctgg agaaactggg aagaatggtg 6850

 gctttggccg aaggggaccc cccggagcta agggcaacaa gggcggtcct 6900

 ggccagccgg gctttgaggg agagcagggg accagaggtg cacagggccc 6950

 agctggtcct gctggtcctc cagggctgat aggagaacaa ggcatttctg 7000

 gacctagggg aagcggaggt gcccgtggcg ctcctggaga acgaggcaga 7050

 accggtccac tgggaagaaa gggtgagccc ggagagccag gaccaaaagg 7100

 aggaatcggg aacccgggcc ctcgtgggga gacgggagat gacgggagag 7150

 acggagttgg cagtgaagga cgcagaggca aaaaaggaga aagaggattt 7200

 cctggatacc caggaccaaa gggtaaccca ggtgaacctg ggctaaatgg 7250

 aacaacagga cccaaaggca tcagaggccg aaggggaaat tcgggacctc 7300

 cagggatagt tggacagaag gggagacctg gctacccagg accagctggt 7350

 ccaaggggca acaggggcga ctccatcgat caatgtgccc tcatccaaag 7400

 catcaaagat aaatgccctt gctgttacgg gcccctggag tgccccgtct 7450

 tcccaacaga actagccttt gctttagaca cctctgaggg agtcaaccaa 7500

 gacactttcg gccggatgcg agatgtggtc ttgagtattg tgaatgtcct 7550

 gaccattgct gagagcaact gcccgacggg ggcccgggtg gctgtggtca 7600

 cctacaacaa cgaggtgacc acggagatcc ggtttgctga ctccaagagg 7650

 aagtcggtcc tcctggacaa gattaagaac cttcaggtgg ctctgacatc 7700

 caaacagcag agtctggaga ctgccatgtc gtttgtggcc aggaacacat 7750

 ttaagcgtgt gaggaacgga ttcctaatga ggaaagtggc tgttttcttc 7800

 agcaacacac ccacaagagc atccccacag ctcagagagg ctgtgctcaa 7850

 actctcagat gcggggatca cccccttgtt ccttacaagg caggaagacc 7900

 ggcagctcat caacgctttg cagatcaata acacagcagt ggggcatgcg 7950

 cttgtcctgc ctgcagggag agacctcaca gacttcctgg agaatgtcct 8000

 cacgtgtcat gtttgcttgg acatctgcaa catcgaccca tcctgtggat 8050

 ttggcagttg gaggccttcc ttcagggaca ggagagcggc agggagtgat 8100

 gtggacatcg acatggcttt catcttagac agcgctgaga ccaccaccct 8150

 gttccagttc aatgagatga agaagtacat agcgtacctg gtcagacaac 8200

 tggacatgag cccagatccc aaggcctccc agcacttcgc cagagtggca 8250

 gttgtgcagc acgcgccctc tgagtccgtg gacaatgcca gcatgccacc 8300

 tgtgaaggtg gaattctccc tgactgacta tggctccaag gagaagctgg 8350

 tggacttcct cagcagggga atgacacagt tgcagggaac cagggcctta 8400

 ggcagtgcca ttgaatacac catagagaat gtctttgaaa gtgccccaaa 8450

 cccacgggac ctgaaaattg tggtcctgat gctgacgggc gaggtgccgg 8500

 agcagcagct ggaggaggcc cagagagtca tcctgcaggc caaatgcaag 8550

 ggctacttct tcgtggtcct gggcattggc aggaaggtga acatcaagga 8600

 ggtatacacc ttcgccagtg agccaaacga cgtcttcttc aaattagtgg 8650

 acaagtccac cgagctcaac gaggagcctt tgatgcgctt cgggaggctg 8700

 ttgccgtcct tcgtcagcag tgaaaatgct ttttacttgt ccccagatat 8750

 caggaaacag tgtgattggt tccaagggga ccaacccaca aagaaccttg 8800

 tgaagtttgg tcacaaacaa gtaaatgttc cgaataacgt tacttcaagt 8850

 cctacatcca acccagtgac gacaacgaag ccggtgacta cgacgaagcc 8900

 ggtgaccacc acaacaaagc ctgtaaccac cacaacaaag cctgtgacta 8950

 ttataaatca gccatctgtg aagccagccg ctgcaaagcc ggcccctgcg 9000

 aaacctgtgg ctgccaagcc tgtggccaca aagacggcca ctgttagacc 9050

 cccagtggcg gtgaagccag caacagcagc gaagcctgta gcagcaaagc 9100

 cagcagctgt aagacccccc gctgctgctg caaaaccagt ggcgaccaag 9150

 cctgaggtcc ctaggccaca ggcagccaaa ccagctgcca ccaagccagc 9200

 caccactaag cccgtggtta agatgctccg tgaagtccag gtgtttgaga 9250

 taacagagaa cagcgccaaa ctccactggg agaggcctga gccccccggt 9300

 ccttattttt atgacctcac cgtcacctca gcccatgatc agtccctggt 9350

 tctgaagcag aacctcacgg tcacggaccg cgtcattgga ggcctgctcg 9400

 ctgggcagac ataccatgtg gctgtggtct gctacctgag gtctcaggtc 9450

 agagccacct accacggaag tttcagtaca aagaaatctc agcccccacc 9500

 tccacagcca gcaaggtcag cttctagttc aaccatcaat ctaatggtga 9550

 gcacagaacc attggctctc actgaaacag atatatgcaa gttgccgaaa 9600

 gacgaaggaa cttgcaggga tttcatatta aaatggtact atgatccaaa 9650

 caccaaaagc tgtgcaagat tctggtatgg aggttgtggt ggaaacgaaa 9700

 acaaatttgg atcacagaaa gaatgtgaaa aggtttgcgc tcctgtgctc 9750

 gccaaacccg gagtcatcag tgtgatggga acctaagcgt gggtggccaa 9800

 catcatatac ctcttgaaga agaaggagtc agccatcgcc aacttgtctc 9850

 tgtagaagct ccgggtgtag attcccttgc actgtatcat ttcatgcttt 9900

 gatttacact cgaactcggg agggaacatc ctgctgcatg acctatcagt 9950

 atggtgctaa tgtgtctgtg gaccctcgct ctctgtctcc agcagttctc 10000

 tcgaatactt tgaatgttgt gtaacagtta gccactgctg gtgtttatgt 10050

 gaacattcct atcaatccaa attccctctg gagtttcatg ttatgcctgt 10100

 tgcaggcaaa tgtaaagtct agaaaataat gcaaatgtca cggctactct 10150

 atatactttt gcttggttca ttttttttcc cttttagtta agcatgactt 10200

 tagatgggaa gcctgtgtat cgtggagaaa caagagacca actttttcat 10250

 tccctgcccc caatttccca gactagattt caagctaatt ttctttttct 10300

 gaagcctcta acaaatgatc tagttcagaa ggaagcaaaa tcccttaatc 10350

 tatgtgcacc gttgggacca atgccttaat taaagaattt aaaaaagttg 10400

 taatagagaa tatttttggc attcctctca atgttgtgtg tttttttttt 10450

 ttgtgtgctg gagggagggg atttaatttt aattttaaaa tgtttaggaa 10500

 atttatacaa agaaactttt taataaagta tattgaaagt ttaaaaaaaa 10550

 aaaaaaaa 10558

<210> 326
<211> 2000
<212> PRT
<213> Homo sapien

<400> 326
 Met Arg Lys His Arg His Leu Pro Leu Val Ala Val Phe Cys Leu
   1               5                  10                  15

 Phe Leu Ser Gly Phe Pro Thr Thr His Ala Gln Gln Gln Gln Ala
                  20                  25                  30

 Asp Val Lys Asn Gly Ala Ala Ala Asp Ile Ile Phe Leu Val Asp
                  35                  40                  45

 Ser Ser Trp Thr Ile Gly Glu Glu His Phe Gln Leu Val Arg Glu
                  50                  55                  60

 Phe Leu Tyr Asp Val Val Lys Ser Leu Ala Val Gly Glu Asn Asp
                  65                  70                  75

 Phe His Phe Ala Leu Val Gln Phe Asn Gly Asn Pro His Thr Glu
                  80                  85                  90

 Phe Leu Leu Asn Thr Tyr Arg Thr Lys Gln Glu Val Leu Ser His
                  95                 100                 105

 Ile Ser Asn Met Ser Tyr Ile Gly Gly Thr Asn Gln Thr Gly Lys
                 110                 115                 120

 Gly Leu Glu Tyr Ile Met Gln Ser His Leu Thr Lys Ala Ala Gly
                 125                 130                 135

 Ser Arg Ala Gly Asp Gly Val Pro Gln Val Ile Val Val Leu Thr
                 140                 145                 150

 Asp Gly His Ser Lys Asp Gly Leu Ala Leu Pro Ser Ala Glu Leu
                 155                 160                 165

 Lys Ser Ala Asp Val Asn Val Phe Ala Ile Gly Val Glu Asp Ala
                 170                 175                 180

 Asp Glu Gly Ala Leu Lys Glu Ile Ala Ser Glu Pro Leu Asn Met
                 185                 190                 195

 His Met Phe Asn Leu Glu Asn Phe Thr Ser Leu His Asp Ile Val
                 200                 205                 210

 Gly Asn Leu Val Ser Cys Val His Ser Ser Val Ser Pro Glu Arg
                 215                 220                 225

 Ala Gly Asp Thr Glu Thr Leu Lys Asp Ile Thr Ala Gln Asp Ser
                 230                 235                 240

 Ala Asp Ile Ile Phe Leu Ile Asp Gly Ser Asn Asn Thr Gly Ser
                 245                 250                 255

 Val Asn Phe Ala Val Ile Leu Asp Phe Leu Val Asn Leu Leu Glu
                 260                 265                 270

 Lys Leu Pro Ile Gly Thr Gln Gln Ile Arg Val Gly Val Val Gln
                 275                 280                 285

 Phe Ser Asp Glu Pro Arg Thr Met Phe Ser Leu Asp Thr Tyr Ser
                 290                 295                 300

 Thr Lys Ala Gln Val Leu Gly Ala Val Lys Ala Leu Gly Phe Ala
                 305                 310                 315

 Gly Gly Glu Leu Ala Asn Ile Gly Leu Ala Leu Asp Phe Val Val
                 320                 325                 330

 Glu Asn His Phe Thr Arg Ala Gly Gly Ser Arg Val Glu Glu Gly
                 335                 340                 345

 Val Pro Gln Val Leu Val Leu Ile Ser Ala Gly Pro Ser Ser Asp
                 350                 355                 360

 Glu Ile Arg Tyr Gly Val Val Ala Leu Lys Gln Ala Ser Val Phe
                 365                 370                 375

 Ser Phe Gly Leu Gly Ala Gln Ala Ala Ser Arg Ala Glu Leu Gln
                 380                 385                 390

 His Ile Ala Thr Asp Asp Asn Leu Val Phe Thr Val Pro Glu Phe
                 395                 400                 405

 Arg Ser Phe Gly Asp Leu Gln Glu Lys Leu Leu Pro Tyr Ile Val
                 410                 415                 420

 Gly Val Ala Gln Arg His Ile Val Leu Lys Pro Pro Thr Ile Val
                 425                 430                 435

 Thr Gln Val Ile Glu Val Asn Lys Arg Asp Ile Val Phe Leu Val
                 440                 445                 450

 Asp Gly Ser Ser Ala Leu Gly Leu Ala Asn Phe Asn Ala Ile Arg
                 455                 460                 465

 Asp Phe Ile Ala Lys Val Ile Gln Arg Leu Glu Ile Gly Gln Asp
                 470                 475                 480

 Leu Ile Gln Val Ala Val Ala Gln Tyr Ala Asp Thr Val Arg Pro
                 485                 490                 495

 Glu Phe Tyr Phe Asn Thr His Pro Thr Lys Arg Glu Val Ile Thr
                 500                 505                 510

 Ala Val Arg Lys Met Lys Pro Leu Asp Gly Ser Ala Leu Tyr Thr
                 515                 520                 525

 Gly Ser Ala Leu Asp Phe Val Arg Asn Asn Leu Phe Thr Ser Ser
                 530                 535                 540

 Ala Gly Tyr Arg Ala Ala Glu Gly Ile Pro Lys Leu Leu Val Leu
                 545                 550                 555

 Ile Thr Gly Gly Lys Ser Leu Asp Glu Ile Ser Gln Pro Ala Gln
                 560                 565                 570

 Glu Leu Lys Arg Ser Ser Ile Met Ala Phe Ala Ile Gly Asn Lys
                 575                 580                 585

 Gly Ala Asp Gln Ala Glu Leu Glu Glu Ile Ala Phe Asp Ser Ser
                 590                 595                 600

 Leu Val Phe Ile Pro Ala Glu Phe Arg Ala Ala Pro Leu Gln Gly
                 605                 610                 615

 Met Leu Pro Gly Leu Leu Ala Pro Leu Arg Thr Leu Ser Gly Thr
                 620                 625                 630

 Pro Glu Val His Ser Asn Lys Arg Asp Ile Ile Phe Leu Leu Asp
                 635                 640                 645

 Gly Ser Ala Asn Val Gly Lys Thr Asn Phe Pro Tyr Val Arg Asp
                 650                 655                 660

 Phe Val Met Asn Leu Val Asn Ser Leu Asp Ile Gly Asn Asp Asn
                 665                 670                 675

 Ile Arg Val Gly Leu Val Gln Phe Ser Asp Thr Pro Val Thr Glu
                 680                 685                 690

 Phe Ser Leu Asn Thr Tyr Gln Thr Lys Ser Asp Ile Leu Gly His
                 695                 700                 705

 Leu Arg Gln Leu Gln Leu Gln Gly Gly Ser Gly Leu Asn Thr Gly
                 710                 715                 720

 Ser Ala Leu Ser Tyr Val Tyr Ala Asn His Phe Thr Glu Ala Gly
                 725                 730                 735

 Gly Ser Arg Ile Arg Glu His Val Pro Gln Leu Leu Leu Leu Leu
                 740                 745                 750

 Thr Ala Gly Gln Ser Glu Asp Ser Tyr Leu Gln Ala Ala Asn Ala
                 755                 760                 765

 Leu Thr Arg Ala Gly Ile Leu Thr Phe Cys Val Gly Ala Ser Gln
                 770                 775                 780

 Ala Asn Lys Ala Glu Leu Glu Gln Ile Ala Phe Asn Pro Ser Leu
                 785                 790                 795

 Val Tyr Leu Met Asp Asp Phe Ser Ser Leu Pro Ala Leu Pro Gln
                 800                 805                 810

 Gln Leu Ile Gln Pro Leu Thr Thr Tyr Val Ser Gly Gly Val Glu
                 815                 820                 825

 Glu Val Pro Leu Ala Gln Pro Glu Ser Lys Arg Asp Ile Leu Phe
                 830                 835                 840

 Leu Phe Asp Gly Ser Ala Asn Leu Val Gly Gln Phe Pro Val Val
                 845                 850                 855

 Arg Asp Phe Leu Tyr Lys Ile Ile Asp Glu Leu Asn Val Lys Pro
                 860                 865                 870

 Glu Gly Thr Arg Ile Ala Val Ala Gln Tyr Ser Asp Asp Val Lys
                 875                 880                 885

 Val Glu Ser Arg Phe Asp Glu His Gln Ser Lys Pro Glu Ile Leu
                 890                 895                 900

 Asn Leu Val Lys Arg Met Lys Ile Lys Thr Gly Lys Ala Leu Asn
                 905                 910                 915

 Leu Gly Tyr Ala Leu Asp Tyr Ala Gln Arg Tyr Ile Phe Val Lys
                 920                 925                 930

 Ser Ala Gly Ser Arg Ile Glu Asp Gly Val Leu Gln Phe Leu Val
                 935                 940                 945

 Leu Leu Val Ala Gly Arg Ser Ser Asp Arg Val Asp Gly Pro Ala
                 950                 955                 960

 Ser Asn Leu Lys Gln Ser Gly Val Val Pro Phe Ile Phe Gln Ala
                 965                 970                 975

 Lys Asn Ala Asp Pro Ala Glu Leu Glu Gln Ile Val Leu Ser Pro
                 980                 985                 990

 Ala Phe Ile Leu Ala Ala Glu Ser Leu Pro Lys Ile Gly Asp Leu
                 995                1000                1005

 His Pro Gln Ile Val Asn Leu Leu Lys Ser Val His Asn Gly Ala
                1010                1015                1020

 Pro Ala Pro Val Ser Gly Glu Lys Asp Val Val Phe Leu Leu Asp
                1025                1030                1035

 Gly Ser Glu Gly Val Arg Ser Gly Phe Pro Leu Leu Lys Glu Phe
                1040                1045                1050

 Val Gln Arg Val Val Glu Ser Leu Asp Val Gly Gln Asp Arg Val
                1055                1060                1065

 Arg Val Ala Val Val Gln Tyr Ser Asp Arg Thr Arg Pro Glu Phe
                1070                1075                1080

 Tyr Leu Asn Ser Tyr Met Asn Lys Gln Asp Val Val Asn Ala Val
                1085                1090                1095

 Arg Gln Leu Thr Leu Leu Gly Gly Pro Thr Pro Asn Thr Gly Ala
                1100                1105                1110

 Ala Leu Glu Phe Val Leu Arg Asn Ile Leu Val Ser Ser Ala Gly
                1115                1120                1125

 Ser Arg Ile Thr Glu Gly Val Pro Gln Leu Leu Ile Val Leu Thr
                1130                1135                1140

 Ala Asp Arg Ser Gly Asp Asp Val Arg Asn Pro Ser Val Val Val
                1145                1150                1155

 Lys Arg Gly Gly Ala Val Pro Ile Gly Ile Gly Ile Gly Asn Ala
                1160                1165                1170

 Asp Ile Thr Glu Met Gln Thr Ile Ser Phe Ile Pro Asp Phe Ala
                1175                1180                1185

 Val Ala Ile Pro Thr Phe Arg Gln Leu Gly Thr Val Gln Gln Val
                1190                1195                1200

 Ile Ser Glu Arg Val Thr Gln Leu Thr Arg Glu Glu Leu Ser Arg
                1205                1210                1215

 Leu Gln Pro Val Leu Gln Pro Leu Pro Ser Pro Gly Val Gly Gly
                1220                1225                1230

 Lys Arg Asp Val Val Phe Leu Ile Asp Gly Ser Gln Ser Ala Gly
                1235                1240                1245

 Pro Glu Phe Gln Tyr Val Arg Thr Leu Ile Glu Arg Leu Val Asp
                1250                1255                1260

 Tyr Leu Asp Val Gly Phe Asp Thr Thr Arg Val Ala Val Ile Gln
                1265                1270                1275

 Phe Ser Asp Asp Pro Lys Ala Glu Phe Leu Leu Asn Ala His Ser
                1280                1285                1290

 Ser Lys Asp Glu Val Gln Asn Ala Val Gln Arg Leu Arg Pro Lys
                1295                1300                1305

 Gly Gly Arg Gln Ile Asn Val Gly Asn Ala Leu Glu Tyr Val Ser
                1310                1315                1320

 Arg Asn Ile Phe Lys Arg Pro Leu Gly Ser Arg Ile Glu Glu Gly
                1325                1330                1335

 Val Pro Gln Phe Leu Val Leu Ile Ser Ser Gly Lys Ser Asp Asp
                1340                1345                1350

 Glu Val Val Val Pro Ala Val Glu Leu Lys Gln Phe Gly Val Ala
                1355                1360                1365

 Pro Phe Thr Ile Ala Arg Asn Ala Asp Gln Glu Glu Leu Val Lys
                1370                1375                1380

 Ile Ser Leu Ser Pro Glu Tyr Val Phe Ser Val Ser Thr Phe Arg
                1385                1390                1395

 Glu Leu Pro Ser Leu Glu Gln Lys Leu Leu Thr Pro Ile Thr Thr
                1400                1405                1410

 Leu Thr Ser Glu Gln Ile Gln Lys Leu Leu Ala Ser Thr Arg Tyr
                1415                1420                1425

 Pro Pro Pro Ala Val Glu Ser Asp Ala Ala Asp Ile Val Phe Leu
                1430                1435                1440

 Ile Asp Ser Ser Glu Gly Val Arg Pro Asp Gly Phe Ala His Ile
                1445                1450                1455

 Arg Asp Phe Val Ser Arg Ile Val Arg Arg Leu Asn Ile Gly Pro
                1460                1465                1470

 Ser Lys Val Arg Val Gly Val Val Gln Phe Ser Asn Asp Val Phe
                1475                1480                1485

 Pro Glu Phe Tyr Leu Lys Thr Tyr Arg Ser Gln Ala Pro Val Leu
                1490                1495                1500

 Asp Ala Ile Arg Arg Leu Arg Leu Arg Gly Gly Ser Pro Leu Asn
                1505                1510                1515

 Thr Gly Lys Ala Leu Glu Phe Val Ala Arg Asn Leu Phe Val Lys
                1520                1525                1530

 Ser Ala Gly Ser Arg Ile Glu Asp Gly Val Pro Gln His Leu Val
                1535                1540                1545

 Leu Val Leu Gly Gly Lys Ser Gln Asp Asp Val Ser Arg Phe Ala
                1550                1555                1560

 Gln Val Ile Arg Ser Ser Gly Ile Val Ser Leu Gly Val Gly Asp
                1565                1570                1575

 Arg Asn Ile Asp Arg Thr Glu Leu Gln Thr Ile Thr Asn Asp Pro
                1580                1585                1590

 Arg Leu Val Phe Thr Val Arg Glu Phe Arg Glu Leu Pro Asn Ile
                1595                1600                1605

 Glu Glu Arg Ile Met Asn Ser Phe Gly Pro Ser Ala Ala Thr Pro
                1610                1615                1620

 Ala Pro Pro Gly Val Asp Thr Pro Pro Pro Ser Arg Pro Glu Lys
                1625                1630                1635

 Lys Lys Ala Asp Ile Val Phe Leu Leu Asp Gly Ser Ile Asn Phe
                1640                1645                1650

 Arg Arg Asp Ser Phe Gln Glu Val Leu Arg Phe Val Ser Glu Ile
                1655                1660                1665

 Val Asp Thr Val Tyr Glu Asp Gly Asp Ser Ile Gln Val Gly Leu
                1670                1675                1680

 Val Gln Tyr Asn Ser Asp Pro Thr Asp Glu Phe Phe Leu Lys Asp
                1685                1690                1695

 Phe Ser Thr Lys Arg Gln Ile Ile Asp Ala Ile Asn Lys Val Val
                1700                1705                1710

 Tyr Lys Gly Gly Arg His Ala Asn Thr Lys Val Gly Leu Glu His
                1715                1720                1725

 Leu Arg Val Asn His Phe Val Pro Glu Ala Gly Ser Arg Leu Asp
                1730                1735                1740

 Gln Arg Val Pro Gln Ile Ala Phe Val Ile Thr Gly Gly Lys Ser
                1745                1750                1755

 Val Glu Asp Ala Gln Asp Val Ser Leu Ala Leu Thr Gln Arg Gly
                1760                1765                1770

 Val Lys Val Phe Ala Val Gly Val Arg Asn Ile Asp Ser Glu Glu
                1775                1780                1785

 Val Gly Lys Ile Ala Ser Asn Ser Ala Thr Ala Phe Arg Val Gly
                1790                1795                1800

 Asn Val Gln Glu Leu Ser Glu Leu Ser Glu Gln Val Leu Glu Thr
                1805                1810                1815

 Leu His Asp Ala Met His Glu Thr Leu Cys Pro Gly Val Thr Asp
                1820                1825                1830

 Ala Ala Lys Ala Cys Asn Leu Asp Val Ile Leu Gly Phe Asp Gly
                1835                1840                1845

 Ser Arg Asp Gln Asn Val Phe Val Ala Gln Lys Gly Phe Glu Ser
                1850                1855                1860

 Lys Val Asp Ala Ile Leu Asn Arg Ile Ser Gln Met His Arg Val
                1865                1870                1875

 Ser Cys Ser Gly Gly Arg Ser Pro Thr Val Arg Val Ser Val Val
                1880                1885                1890

 Ala Asn Thr Pro Ser Gly Pro Val Glu Ala Phe Asp Phe Asp Glu
                1895                1900                1905

 Tyr Gln Pro Glu Met Leu Glu Lys Phe Arg Asn Met Arg Ser Gln
                1910                1915                1920

 His Pro Tyr Val Leu Thr Glu Asp Thr Leu Lys Val Tyr Leu Asn
                1925                1930                1935

 Lys Phe Arg Gln Ser Ser Pro Asp Ser Val Lys Val Val Ile His
                1940                1945                1950

 Phe Thr Asp Gly Ala Asp Gly Asp Leu Ala Asp Leu His Arg Ala
                1955                1960                1965

 Ser Glu Asn Leu Arg Gln Glu Gly Val Arg Ala Leu Ile Leu Val
                1970                1975                1980

 Gly Leu Glu Arg Val Val Asn Leu Glu Arg Leu Met His Leu Glu
                1985                1990                1995

 Phe Gly Arg Gly Phe
                2000

<210> 327
<211> 2390
<212> DNA
<213> Homo sapien

<400> 327
 attggggttt cattgttccc gctgggccgg gcggtttagt gtaattgccg 50

 ccggaggagg aggcggagta acctctggtc agccgagaaa ccccactatc 100

 ctgtagccat aaccgcttaa acgatttggg aggtagtgaa gggcagggag 150

 ctggacctgg aggcgccgcc gcgacagcag cagccatgga ggacgagatg 200

 cccaagactc tatacgtcgg taacctttcc agagatgtga cagaagctct 250

 aattctgcaa ctctttagcc agattggacc ttgtaaaaac tgcaaaatga 300

 ttatggatac agctggaaat gatccctatt gttttgtgga gtttcatgag 350

 catcgtcatg cagctgcagc attagctgct atgaatggac ggaagataat 400

 gggtaaggaa gtcaaagtga attgggcaac aacccctagc agtcaaaaga 450

 aagatacaag cagtagtacc gttgtcagca cacagcgttc acaagatcat 500

 ttccatgtct ttgttggtga tctcagccca caaattacaa ctgaagatat 550

 aaaagctgct tttgcaccat ttggaagaat atcagatgcc cgagtggtaa 600

 aagacatggc aacaggaaag tctaagggat atggctttgt ctcctttttc 650

 aacaaatggg atgctgaaaa cgccattcaa cagatgggtg gccagtggct 700

 tggtggaaga caaatcagaa ctaactgggc aacccgaaag cctcccgctc 750

 caaagagtac atatgagtca aataccaaac agctatcata tgatgaggtt 800

 gtaaatcagt ctagtccaag caactgtact gtatactgtg gaggtgttac 850

 ttctgggcta acagaacaac taatgcgtca gactttttca ccatttggac 900

 aaataatgga aattcgagtc tttccagata aaggatattc atttgttcgg 950

 ttcaattccc atgaaagtgc agcacatgca attgtttctg ttaatggtac 1000

 taccattgaa ggtcatgttg tgaaatgcta ttggggcaaa gaaactcttg 1050

 atatgataaa tcccgtgcaa cagcagaatc aaattggata tccccaacct 1100

 tatggccagt ggggccagtg gtatggaaat gcacaacaaa ttggccagta 1150

 tatgcctaat ggttggcaag ttcctgcata tggaatgtat ggccaggcat 1200

 ggaaccagca aggatttaat cagacacagt cttctgcacc atggatggga 1250

 ccaaattatg gagtgcaacc gcctcaaggg caaaatggca gcatgttgcc 1300

 caatcagcct tctgggtatc gagtggcagg gtatgaaacc cagtgaataa 1350

 ggactccaga atctaaagcc agtggcttga ggctacaggg agtgtagtaa 1400

 agccgttgtt tacttaaaga tttatcaaat cagtcagtgc aaatgtcaga 1450

 tacaatgtat tcatttaaaa gattcatttt taatcatgaa attacttatc 1500

 atccacattg ttttaaaaag aaacaagatg ctggatgtct gccaattttt 1550

 gccttcatta ccttttttga taaagtttct cagatccttg tttcaaacac 1600

 aaatgcaggg attgctgcca ctttttaact attaagaggc agaaaattgc 1650

 acaatattga acttttttcc actgaagtag tgtgcagttc tagtttgcat 1700

 tcctgatatg atttaaaaca tgtaatataa agatgttaaa aaaaaaaacc 1750

 aaaactgtgc agagtctaga agttgtttgt catcttcagc ttgtgcacaa 1800

 ttctgtttta ggttaaaaaa aggcattgtt tgagctgtcc catctccact 1850

 gttatccctt tgggtttttt aatataaatt attagtttac atcatttttg 1900

 tatctacatc ttttttcaca aatttgtctt gccttattaa agttctgtaa 1950

 aatatactta aatggaaaaa atgatgttca tttagattga aaacttttct 2000

 cagatggatt gataattgca ttcatcttgt gttttatatg agaaggtgcc 2050

 tcaagaattt cctgttggat ttgtttaaaa ggatttttat ctttcgtgat 2100

 aaactttgct gtgtaccagg aactataaaa acaaaaactt gttactaaag 2150

 aaaatatctg aaatgtgata agttcttatg ccatgttaat ttcatgtgtc 2200

 aacttcaaca tttacatgta ttatttcatt atgtaaaatg ttttagcaat 2250

 ttaatatttt gcacagttag caaactttgt atgtcatttc cttcaaggca 2300

 tcatgcagag ttgacatgag atttataagg ttttaagttg tttgcatgtg 2350

 aaaatcaaat acatactttg gtagtctttg aaaaaaaaaa 2390

<210> 328
<211> 386
<212> PRT
<213> Homo sapien

<400> 328
 Met Glu Asp Glu Met Pro Lys Thr Leu Tyr Val Gly Asn Leu Ser
   1               5                  10                  15

 Arg Asp Val Thr Glu Ala Leu Ile Leu Gln Leu Phe Ser Gln Ile
                  20                  25                  30

 Gly Pro Cys Lys Asn Cys Lys Met Ile Met Asp Thr Ala Gly Asn
                  35                  40                  45

 Asp Pro Tyr Cys Phe Val Glu Phe His Glu His Arg His Ala Ala
                  50                  55                  60

 Ala Ala Leu Ala Ala Met Asn Gly Arg Lys Ile Met Gly Lys Glu
                  65                  70                  75

 Val Lys Val Asn Trp Ala Thr Thr Pro Ser Ser Gln Lys Lys Asp
                  80                  85                  90

 Thr Ser Ser Ser Thr Val Val Ser Thr Gln Arg Ser Gln Asp His
                  95                 100                 105

 Phe His Val Phe Val Gly Asp Leu Ser Pro Gln Ile Thr Thr Glu
                 110                 115                 120

 Asp Ile Lys Ala Ala Phe Ala Pro Phe Gly Arg Ile Ser Asp Ala
                 125                 130                 135

 Arg Val Val Lys Asp Met Ala Thr Gly Lys Ser Lys Gly Tyr Gly
                 140                 145                 150

 Phe Val Ser Phe Phe Asn Lys Trp Asp Ala Glu Asn Ala Ile Gln
                 155                 160                 165

 Gln Met Gly Gly Gln Trp Leu Gly Gly Arg Gln Ile Arg Thr Asn
                 170                 175                 180

 Trp Ala Thr Arg Lys Pro Pro Ala Pro Lys Ser Thr Tyr Glu Ser
                 185                 190                 195

 Asn Thr Lys Gln Leu Ser Tyr Asp Glu Val Val Asn Gln Ser Ser
                 200                 205                 210

 Pro Ser Asn Cys Thr Val Tyr Cys Gly Gly Val Thr Ser Gly Leu
                 215                 220                 225

 Thr Glu Gln Leu Met Arg Gln Thr Phe Ser Pro Phe Gly Gln Ile
                 230                 235                 240

 Met Glu Ile Arg Val Phe Pro Asp Lys Gly Tyr Ser Phe Val Arg
                 245                 250                 255

 Phe Asn Ser His Glu Ser Ala Ala His Ala Ile Val Ser Val Asn
                 260                 265                 270

 Gly Thr Thr Ile Glu Gly His Val Val Lys Cys Tyr Trp Gly Lys
                 275                 280                 285

 Glu Thr Leu Asp Met Ile Asn Pro Val Gln Gln Gln Asn Gln Ile
                 290                 295                 300

 Gly Tyr Pro Gln Pro Tyr Gly Gln Trp Gly Gln Trp Tyr Gly Asn
                 305                 310                 315

 Ala Gln Gln Ile Gly Gln Tyr Met Pro Asn Gly Trp Gln Val Pro
                 320                 325                 330

 Ala Tyr Gly Met Tyr Gly Gln Ala Trp Asn Gln Gln Gly Phe Asn
                 335                 340                 345

 Gln Thr Gln Ser Ser Ala Pro Trp Met Gly Pro Asn Tyr Gly Val
                 350                 355                 360

 Gln Pro Pro Gln Gly Gln Asn Gly Ser Met Leu Pro Asn Gln Pro
                 365                 370                 375

 Ser Gly Tyr Arg Val Ala Gly Tyr Glu Thr Gln
                 380                 385

<210> 329
<211> 1488
<212> DNA
<213> Homo sapien

<400> 329
 gttggtgagc atcatggcaa ccgttacagc cacaaccaaa gtcccggaga 50

 tccgtgatgt aacaaggatt gagcgaatcg gtgcccactc ccacatccgg 100

 ggactggggc tggacgatgc cttggagcct cggcaggctt cgcaaggcat 150

 ggtgggtcag ctggcggcac ggcgggcggc tggcgtggtg ctggagatga 200

 tccgggaagg gaagattgcc ggtcgggcag tccttattgc tggccagccg 250

 ggcacgggga agacggccat cgccatgggc atggcgcagg ccctgggccc 300

 tgacacgcca ttcacagcca tcgccggcag tgaaatcttc tccctggaga 350

 tgagcaagac cgaggcgctg acgcaggcct tccggcggtc catcggcgtt 400

 cgcatcaagg aggagacgga gatcatcgaa ggggaggtgg tggagatcca 450

 gattgatcga ccagcaacag ggacgggctc caaggtgggc aaactgaccc 500

 tcaagaccac agagatggag accatctacg acctgggcac caagatgatt 550

 gagtccctga ccaaggacaa ggtccaggcc ggggacgtga tcaccatcga 600

 caaggcgacg ggcaagatct ccaagctggg ccgctccttc acacgcgccc 650

 gcgactacga cgctatgggc tcccagacca agttcgtgca gtgcccagat 700

 ggggagctcc agaaacgcaa ggaggtggtg cacaccgtgt ccctgcacga 750

 gatcgacgtc atcaactctc gcacccaggg cttcctggcg ctcttctcag 800

 gtgacacagg ggagatcaag tcagaagtcc gtgagcagat caatgccaag 850

 gtggctgagt ggcgcgagga gggcaaggcg gagatcatcc ctggagtgct 900

 gttcatcgac gaggtccaca tgctggacat cgagagcttc tccttcctca 950

 accgggccct ggagagtgac atggcgcctg tcctgatcat ggccaccaac 1000

 cgtggcatca cgcgaatccg gggcaccagc taccagagcc ctcacggcat 1050

 ccccatagac ctgctggacc ggctgcttat cgtctccacc accccctaca 1100

 gcgagaaaga cacgaagcag atcctccgca tccggtgcga ggaagaagat 1150

 gtggagatga gtgaggacgc ctacacggtg ctgacccgca tcgggctgga 1200

 gacgtcactg cgctacgcca tccagctcat cacagctgcc agcttggtgt 1250

 gccggaaacg caagggtaca gaagtgcagg tggatgacat caagcgggtc 1300

 tactcactct tcctggacga gtcccgctcc acgcagtaca tgaaggagta 1350

 ccaggacgcc ttcctcttca acgaactcaa aggcgagacc atggacacct 1400

 cctgagttgg atgtcatccc ccgaccccac cctgttttcc accagagttc 1450

 tgacactgtg actctgtata aaatggttgg gaagctgc 1488

<210> 330
<211> 463
<212> PRT
<213> Homo sapien

<400> 330
 Met Ala Thr Val Thr Ala Thr Thr Lys Val Pro Glu Ile Arg Asp
   1               5                  10                  15

 Val Thr Arg Ile Glu Arg Ile Gly Ala His Ser His Ile Arg Gly
                  20                  25                  30

 Leu Gly Leu Asp Asp Ala Leu Glu Pro Arg Gln Ala Ser Gln Gly
                  35                  40                  45

 Met Val Gly Gln Leu Ala Ala Arg Arg Ala Ala Gly Val Val Leu
                  50                  55                  60

 Glu Met Ile Arg Glu Gly Lys Ile Ala Gly Arg Ala Val Leu Ile
                  65                  70                  75

 Ala Gly Gln Pro Gly Thr Gly Lys Thr Ala Ile Ala Met Gly Met
                  80                  85                  90

 Ala Gln Ala Leu Gly Pro Asp Thr Pro Phe Thr Ala Ile Ala Gly
                  95                 100                 105

 Ser Glu Ile Phe Ser Leu Glu Met Ser Lys Thr Glu Ala Leu Thr
                 110                 115                 120

 Gln Ala Phe Arg Arg Ser Ile Gly Val Arg Ile Lys Glu Glu Thr
                 125                 130                 135

 Glu Ile Ile Glu Gly Glu Val Val Glu Ile Gln Ile Asp Arg Pro
                 140                 145                 150

 Ala Thr Gly Thr Gly Ser Lys Val Gly Lys Leu Thr Leu Lys Thr
                 155                 160                 165

 Thr Glu Met Glu Thr Ile Tyr Asp Leu Gly Thr Lys Met Ile Glu
                 170                 175                 180

 Ser Leu Thr Lys Asp Lys Val Gln Ala Gly Asp Val Ile Thr Ile
                 185                 190                 195

 Asp Lys Ala Thr Gly Lys Ile Ser Lys Leu Gly Arg Ser Phe Thr
                 200                 205                 210

 Arg Ala Arg Asp Tyr Asp Ala Met Gly Ser Gln Thr Lys Phe Val
                 215                 220                 225

 Gln Cys Pro Asp Gly Glu Leu Gln Lys Arg Lys Glu Val Val His
                 230                 235                 240

 Thr Val Ser Leu His Glu Ile Asp Val Ile Asn Ser Arg Thr Gln
                 245                 250                 255

 Gly Phe Leu Ala Leu Phe Ser Gly Asp Thr Gly Glu Ile Lys Ser
                 260                 265                 270

 Glu Val Arg Glu Gln Ile Asn Ala Lys Val Ala Glu Trp Arg Glu
                 275                 280                 285

 Glu Gly Lys Ala Glu Ile Ile Pro Gly Val Leu Phe Ile Asp Glu
                 290                 295                 300

 Val His Met Leu Asp Ile Glu Ser Phe Ser Phe Leu Asn Arg Ala
                 305                 310                 315

 Leu Glu Ser Asp Met Ala Pro Val Leu Ile Met Ala Thr Asn Arg
                 320                 325                 330

 Gly Ile Thr Arg Ile Arg Gly Thr Ser Tyr Gln Ser Pro His Gly
                 335                 340                 345

 Ile Pro Ile Asp Leu Leu Asp Arg Leu Leu Ile Val Ser Thr Thr
                 350                 355                 360

 Pro Tyr Ser Glu Lys Asp Thr Lys Gln Ile Leu Arg Ile Arg Cys
                 365                 370                 375

 Glu Glu Glu Asp Val Glu Met Ser Glu Asp Ala Tyr Thr Val Leu
                 380                 385                 390

 Thr Arg Ile Gly Leu Glu Thr Ser Leu Arg Tyr Ala Ile Gln Leu
                 395                 400                 405

 Ile Thr Ala Ala Ser Leu Val Cys Arg Lys Arg Lys Gly Thr Glu
                 410                 415                 420

 Val Gln Val Asp Asp Ile Lys Arg Val Tyr Ser Leu Phe Leu Asp
                 425                 430                 435

 Glu Ser Arg Ser Thr Gln Tyr Met Lys Glu Tyr Gln Asp Ala Phe
                 440                 445                 450

 Leu Phe Asn Glu Leu Lys Gly Glu Thr Met Asp Thr Ser
                 455                 460

<210> 331
<211> 3254
<212> DNA
<213> Homo sapien

<400> 331
 agagttgcac tgagtgtggc tgaagcagcg aggcgggagt ggaggtgcgc 50

 ggagtcaggc agacagacag acacagccag ccagccaggt cggcagtata 100

 gtccgaactg caaatcttat tttcttttca ccttctctct aactgcccag 150

 agctagcgcc tgtggctccc gggctggtgg ttcgggagtg tccagagagc 200

 cttgtctcca gccggccccg ggaggagagc cctgctgccc aggcgctgtt 250

 gacagcggcg gaaagcagcg gtaccccacg cgcccgccgg gggacgtcgg 300

 cgagcggctg cagcagcaaa gaactttccc ggcggggagg accggagaca 350

 agtggcagag tcccggagcg aacttttgca agcctttcct gcgtcttagg 400

 cttctccacg gcggtaaaga ccagaaggcg gcggagagcc acgcaagaga 450

 agaaggacgt gcgctcagct tcgctcgcac cggttgttga acttgggcga 500

 gcgcgagccg cggctgccgg gcgccccctc cccctagcag cggaggaggg 550

 gacaagtcgt cggagtccgg gcggccaaga cccgccgccg gccggccact 600

 gcagggtccg cactgatccg ctccgcgggg agagccgctg ctctgggaag 650

 tgagttcgcc tgcggactcc gaggaaccgc tgcgcccgaa gagcgctcag 700

 tgagtgaccg cgacttttca aagccgggta gcgcgcgcga gtcgacaagt 750

 aagagtgcgg gaggcatctt aattaaccct gcgctccctg gagcgagctg 800

 gtgaggaggg cgcagcgggg acgacagcca gcgggtgcgt gcgctcttag 850

 agaaactttc cctgtcaaag gctccggggg gcgcgggtgt cccccgcttg 900

 ccagagccct gttgcggccc cgaaacttgt gcgcgcacgc caaactaacc 950

 tcacgtgaag tgacggactg ttctatgact gcaaagatgg aaacgacctt 1000

 ctatgacgat gccctcaacg cctcgttcct cccgtccgag agcggacctt 1050

 atggctacag taaccccaag atcctgaaac agagcatgac cctgaacctg 1100

 gccgacccag tggggagcct gaagccgcac ctccgcgcca agaactcgga 1150

 cctcctcacc tcgcccgacg tggggctgct caagctggcg tcgcccgagc 1200

 tggagcgcct gataatccag tccagcaacg ggcacatcac caccacgccg 1250

 acccccaccc agttcctgtg ccccaagaac gtgacagatg agcaggaggg 1300

 gttcgccgag ggcttcgtgc gcgccctggc cgaactgcac agccagaaca 1350

 cgctgcccag cgtcacgtcg gcggcgcagc cggtcaacgg ggcaggcatg 1400

 gtggctcccg cggtagcctc ggtggcaggg ggcagcggca gcggcggctt 1450

 cagcgccagc ctgcacagcg agccgccggt ctacgcaaac ctcagcaact 1500

 tcaacccagg cgcgctgagc agcggcggcg gggcgccctc ctacggcgcg 1550

 gccggcctgg cctttcccgc gcaaccccag cagcagcagc agccgccgca 1600

 ccacctgccc cagcagatgc ccgtgcagca cccgcggctg caggccctga 1650

 aggaggagcc tcagacagtg cccgagatgc ccggcgagac accgcccctg 1700

 tcccccatcg acatggagtc ccaggagcgg atcaaggcgg agaggaagcg 1750

 catgaggaac cgcatcgctg cctccaagtg ccgaaaaagg aagctggaga 1800

 gaatcgcccg gctggaggaa aaagtgaaaa ccttgaaagc tcagaactcg 1850

 gagctggcgt ccacggccaa catgctcagg gaacaggtgg cacagcttaa 1900

 acagaaagtc atgaaccacg ttaacagtgg gtgccaactc atgctaacgc 1950

 agcagttgca aacattttga agagagaccg tcgggggctg aggggcaacg 2000

 aagaaaaaaa ataacacaga gagacagact tgagaacttg acaagttgcg 2050

 acggagagaa aaaagaagtg tccgagaact aaagccaagg gtatccaagt 2100

 tggactgggt tcggtctgac ggcgccccca gtgtgcacga gtgggaagga 2150

 cttggtcgcg ccctcccttg gcgtggagcc agggagcggc cgcctgcggg 2200

 ctgccccgct ttgcggacgg gctgtccccg cgcgaacgga acgttggact 2250

 ttcgttaaca ttgaccaaga actgcatgga cctaacattc gatctcattc 2300

 agtattaaag gggggagggg gagggggtta caaactgcaa tagagactgt 2350

 agattgcttc tgtagtactc cttaagaaca caaagcgggg ggagggttgg 2400

 ggaggggcgg caggagggag gtttgtgaga gcgaggctga gcctacagat 2450

 gaactctttc tggcctgctt tcgttaactg tgtatgtaca tatatatatt 2500

 ttttaatttg attaaagctg attactgtca ataaacagct tcatgccttt 2550

 gtaagttatt tcttgtttgt ttgtttgggt atcctgccca gtgttgtttg 2600

 taaataagag atttggagca ctctgagttt accatttgta ataaagtata 2650

 taattttttt atgttttgtt tctgaaaatt ccagaaagga tatttaagaa 2700

 aatacaataa actattggaa agtactcccc taacctcttt tctgcatcat 2750

 ctgtagatcc tagtctatct aggtggagtt gaaagagtta agaatgctcg 2800

 ataaaatcac tctcagtgct tcttactatt aagcagtaaa aactgttctc 2850

 tattagactt agaaataaat gtacctgatg tacctgatgc tatgtcaggc 2900

 ttcatactcc acgctccccc agcgtatcta tatggaattg cttaccaaag 2950

 gctagtgcga tgtttcagga ggctggagga aggggggttg cagtggagag 3000

 ggacagccca ctgagaagtc aaacatttca aagtttggat tgcatcaagt 3050

 ggcatgtgct gtgaccattt ataatgttag aaattttaca ataggtgctt 3100

 attctcaaag caggaattgg tggcagattt tacaaaagat gtatccttcc 3150

 aatttggaat cttctctttg acaattccta gataaaaaga tggcctttgt 3200

 cttatgaata tttataacag cattctgtca caataaatgt attcaaatac 3250

 caat 3254

<210> 332
<211> 331
<212> PRT
<213> Homo sapien

<400> 332
 Met Thr Ala Lys Met Glu Thr Thr Phe Tyr Asp Asp Ala Leu Asn
   1               5                  10                  15

 Ala Ser Phe Leu Pro Ser Glu Ser Gly Pro Tyr Gly Tyr Ser Asn
                  20                  25                  30

 Pro Lys Ile Leu Lys Gln Ser Met Thr Leu Asn Leu Ala Asp Pro
                  35                  40                  45

 Val Gly Ser Leu Lys Pro His Leu Arg Ala Lys Asn Ser Asp Leu
                  50                  55                  60

 Leu Thr Ser Pro Asp Val Gly Leu Leu Lys Leu Ala Ser Pro Glu
                  65                  70                  75

 Leu Glu Arg Leu Ile Ile Gln Ser Ser Asn Gly His Ile Thr Thr
                  80                  85                  90

 Thr Pro Thr Pro Thr Gln Phe Leu Cys Pro Lys Asn Val Thr Asp
                  95                 100                 105

 Glu Gln Glu Gly Phe Ala Glu Gly Phe Val Arg Ala Leu Ala Glu
                 110                 115                 120

 Leu His Ser Gln Asn Thr Leu Pro Ser Val Thr Ser Ala Ala Gln
                 125                 130                 135

 Pro Val Asn Gly Ala Gly Met Val Ala Pro Ala Val Ala Ser Val
                 140                 145                 150

 Ala Gly Gly Ser Gly Ser Gly Gly Phe Ser Ala Ser Leu His Ser
                 155                 160                 165

 Glu Pro Pro Val Tyr Ala Asn Leu Ser Asn Phe Asn Pro Gly Ala
                 170                 175                 180

 Leu Ser Ser Gly Gly Gly Ala Pro Ser Tyr Gly Ala Ala Gly Leu
                 185                 190                 195

 Ala Phe Pro Ala Gln Pro Gln Gln Gln Gln Gln Pro Pro His His
                 200                 205                 210

 Leu Pro Gln Gln Met Pro Val Gln His Pro Arg Leu Gln Ala Leu
                 215                 220                 225

 Lys Glu Glu Pro Gln Thr Val Pro Glu Met Pro Gly Glu Thr Pro
                 230                 235                 240

 Pro Leu Ser Pro Ile Asp Met Glu Ser Gln Glu Arg Ile Lys Ala
                 245                 250                 255

 Glu Arg Lys Arg Met Arg Asn Arg Ile Ala Ala Ser Lys Cys Arg
                 260                 265                 270

 Lys Arg Lys Leu Glu Arg Ile Ala Arg Leu Glu Glu Lys Val Lys
                 275                 280                 285

 Thr Leu Lys Ala Gln Asn Ser Glu Leu Ala Ser Thr Ala Asn Met
                 290                 295                 300

 Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Met Asn His
                 305                 310                 315

 Val Asn Ser Gly Cys Gln Leu Met Leu Thr Gln Gln Leu Gln Thr
                 320                 325                 330

 Phe


<210> 333
<211> 3254
<212> DNA
<213> Homo sapien

<400> 333
 agagttgcac tgagtgtggc tgaagcagcg aggcgggagt ggaggtgcgc 50

 ggagtcaggc agacagacag acacagccag ccagccaggt cggcagtata 100

 gtccgaactg caaatcttat tttcttttca ccttctctct aactgcccag 150

 agctagcgcc tgtggctccc gggctggtgg ttcgggagtg tccagagagc 200

 cttgtctcca gccggccccg ggaggagagc cctgctgccc aggcgctgtt 250

 gacagcggcg gaaagcagcg gtaccccacg cgcccgccgg gggacgtcgg 300

 cgagcggctg cagcagcaaa gaactttccc ggcggggagg accggagaca 350

 agtggcagag tcccggagcg aacttttgca agcctttcct gcgtcttagg 400

 cttctccacg gcggtaaaga ccagaaggcg gcggagagcc acgcaagaga 450

 agaaggacgt gcgctcagct tcgctcgcac cggttgttga acttgggcga 500

 gcgcgagccg cggctgccgg gcgccccctc cccctagcag cggaggaggg 550

 gacaagtcgt cggagtccgg gcggccaaga cccgccgccg gccggccact 600

 gcagggtccg cactgatccg ctccgcgggg agagccgctg ctctgggaag 650

 tgagttcgcc tgcggactcc gaggaaccgc tgcgcccgaa gagcgctcag 700

 tgagtgaccg cgacttttca aagccgggta gcgcgcgcga gtcgacaagt 750

 aagagtgcgg gaggcatctt aattaaccct gcgctccctg gagcgagctg 800

 gtgaggaggg cgcagcgggg acgacagcca gcgggtgcgt gcgctcttag 850

 agaaactttc cctgtcaaag gctccggggg gcgcgggtgt cccccgcttg 900

 ccagagccct gttgcggccc cgaaacttgt gcgcgcacgc caaactaacc 950

 tcacgtgaag tgacggactg ttctatgact gcaaagatgg aaacgacctt 1000

 ctatgacgat gccctcaacg cctcgttcct cccgtccgag agcggacctt 1050

 atggctacag taaccccaag atcctgaaac agagcatgac cctgaacctg 1100

 gccgacccag tggggagcct gaagccgcac ctccgcgcca agaactcgga 1150

 cctcctcacc tcgcccgacg tggggctgct caagctggcg tcgcccgagc 1200

 tggagcgcct gataatccag tccagcaacg ggcacatcac caccacgccg 1250

 acccccaccc agttcctgtg ccccaagaac gtgacagatg agcaggaggg 1300

 gttcgccgag ggcttcgtgc gcgccctggc cgaactgcac agccagaaca 1350

 cgctgcccag cgtcacgtcg gcggcgcagc cggtcaacgg ggcaggcatg 1400

 gtggctcccg cggtagcctc ggtggcaggg ggcagcggca gcggcggctt 1450

 cagcgccagc ctgcacagcg agccgccggt ctacgcaaac ctcagcaact 1500

 tcaacccagg cgcgctgagc agcggcggcg gggcgccctc ctacggcgcg 1550

 gccggcctgg cctttcccgc gcaaccccag cagcagcagc agccgccgca 1600

 ccacctgccc cagcagatgc ccgtgcagca cccgcggctg caggccctga 1650

 aggaggagcc tcagacagtg cccgagatgc ccggcgagac accgcccctg 1700

 tcccccatcg acatggagtc ccaggagcgg atcaaggcgg agaggaagcg 1750

 catgaggaac cgcatcgctg cctccaagtg ccgaaaaagg aagctggaga 1800

 gaatcgcccg gctggaggaa aaagtgaaaa ccttgaaagc tcagaactcg 1850

 gagctggcgt ccacggccaa catgctcagg gaacaggtgg cacagcttaa 1900

 acagaaagtc atgaaccacg ttaacagtgg gtgccaactc atgctaacgc 1950

 agcagttgca aacattttga agagagaccg tcgggggctg aggggcaacg 2000

 aagaaaaaaa ataacacaga gagacagact tgagaacttg acaagttgcg 2050

 acggagagaa aaaagaagtg tccgagaact aaagccaagg gtatccaagt 2100

 tggactgggt tcggtctgac ggcgccccca gtgtgcacga gtgggaagga 2150

 cttggtcgcg ccctcccttg gcgtggagcc agggagcggc cgcctgcggg 2200

 ctgccccgct ttgcggacgg gctgtccccg cgcgaacgga acgttggact 2250

 ttcgttaaca ttgaccaaga actgcatgga cctaacattc gatctcattc 2300

 agtattaaag gggggagggg gagggggtta caaactgcaa tagagactgt 2350

 agattgcttc tgtagtactc cttaagaaca caaagcgggg ggagggttgg 2400

 ggaggggcgg caggagggag gtttgtgaga gcgaggctga gcctacagat 2450

 gaactctttc tggcctgctt tcgttaactg tgtatgtaca tatatatatt 2500

 ttttaatttg attaaagctg attactgtca ataaacagct tcatgccttt 2550

 gtaagttatt tcttgtttgt ttgtttgggt atcctgccca gtgttgtttg 2600

 taaataagag atttggagca ctctgagttt accatttgta ataaagtata 2650

 taattttttt atgttttgtt tctgaaaatt ccagaaagga tatttaagaa 2700

 aatacaataa actattggaa agtactcccc taacctcttt tctgcatcat 2750

 ctgtagatcc tagtctatct aggtggagtt gaaagagtta agaatgctcg 2800

 ataaaatcac tctcagtgct tcttactatt aagcagtaaa aactgttctc 2850

 tattagactt agaaataaat gtacctgatg tacctgatgc tatgtcaggc 2900

 ttcatactcc acgctccccc agcgtatcta tatggaattg cttaccaaag 2950

 gctagtgcga tgtttcagga ggctggagga aggggggttg cagtggagag 3000

 ggacagccca ctgagaagtc aaacatttca aagtttggat tgcatcaagt 3050

 ggcatgtgct gtgaccattt ataatgttag aaattttaca ataggtgctt 3100

 attctcaaag caggaattgg tggcagattt tacaaaagat gtatccttcc 3150

 aatttggaat cttctctttg acaattccta gataaaaaga tggcctttgt 3200

 cttatgaata tttataacag cattctgtca caataaatgt attcaaatac 3250

 caat 3254

<210> 334
<211> 331
<212> PRT
<213> Homo sapien

<400> 334
 Met Thr Ala Lys Met Glu Thr Thr Phe Tyr Asp Asp Ala Leu Asn
   1               5                  10                  15

 Ala Ser Phe Leu Pro Ser Glu Ser Gly Pro Tyr Gly Tyr Ser Asn
                  20                  25                  30

 Pro Lys Ile Leu Lys Gln Ser Met Thr Leu Asn Leu Ala Asp Pro
                  35                  40                  45

 Val Gly Ser Leu Lys Pro His Leu Arg Ala Lys Asn Ser Asp Leu
                  50                  55                  60

 Leu Thr Ser Pro Asp Val Gly Leu Leu Lys Leu Ala Ser Pro Glu
                  65                  70                  75

 Leu Glu Arg Leu Ile Ile Gln Ser Ser Asn Gly His Ile Thr Thr
                  80                  85                  90

 Thr Pro Thr Pro Thr Gln Phe Leu Cys Pro Lys Asn Val Thr Asp
                  95                 100                 105

 Glu Gln Glu Gly Phe Ala Glu Gly Phe Val Arg Ala Leu Ala Glu
                 110                 115                 120

 Leu His Ser Gln Asn Thr Leu Pro Ser Val Thr Ser Ala Ala Gln
                 125                 130                 135

 Pro Val Asn Gly Ala Gly Met Val Ala Pro Ala Val Ala Ser Val
                 140                 145                 150

 Ala Gly Gly Ser Gly Ser Gly Gly Phe Ser Ala Ser Leu His Ser
                 155                 160                 165

 Glu Pro Pro Val Tyr Ala Asn Leu Ser Asn Phe Asn Pro Gly Ala
                 170                 175                 180

 Leu Ser Ser Gly Gly Gly Ala Pro Ser Tyr Gly Ala Ala Gly Leu
                 185                 190                 195

 Ala Phe Pro Ala Gln Pro Gln Gln Gln Gln Gln Pro Pro His His
                 200                 205                 210

 Leu Pro Gln Gln Met Pro Val Gln His Pro Arg Leu Gln Ala Leu
                 215                 220                 225

 Lys Glu Glu Pro Gln Thr Val Pro Glu Met Pro Gly Glu Thr Pro
                 230                 235                 240

 Pro Leu Ser Pro Ile Asp Met Glu Ser Gln Glu Arg Ile Lys Ala
                 245                 250                 255

 Glu Arg Lys Arg Met Arg Asn Arg Ile Ala Ala Ser Lys Cys Arg
                 260                 265                 270

 Lys Arg Lys Leu Glu Arg Ile Ala Arg Leu Glu Glu Lys Val Lys
                 275                 280                 285

 Thr Leu Lys Ala Gln Asn Ser Glu Leu Ala Ser Thr Ala Asn Met
                 290                 295                 300

 Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Met Asn His
                 305                 310                 315

 Val Asn Ser Gly Cys Gln Leu Met Leu Thr Gln Gln Leu Gln Thr
                 320                 325                 330

 Phe


<210> 335
<211> 2870
<212> DNA
<213> Homo sapien

<400> 335
 ggcctgggtg gcgaattcgg cacgaggctc gccgctcgct atggcgtcgc 50

 tcaccgtgaa ggcctacctt ctgggcaagg aggacgcggc gcgcgagatt 100

 cgccgcttca gcttctgctg cagccccgag cctgaggcgg aagccgaggc 150

 tgcggcgggt ccgggaccct gcgagcggct gctgagccgg gtggccgccc 200

 tgttccccgc gctgcggcct ggcggcttcc aggcgcacta ccgcgatgag 250

 gacggggact tggttgcctt ttccagtgac gaggaattga caatggccat 300

 gtcctacgtg aaggatgaca tcttccgaat ctacattaaa gagaaaaaag 350

 agtgccggcg ggaccaccgc ccaccgtgtg ctcaggaggc gccccgcaac 400

 atggtgcacc ccaatgtgat ctgcgatggc tgcaatgggc ctgtggtagg 450

 aacccgctac aagtgcagcg tctgcccaga ctacgacttg tgtagcgtct 500

 gcgagggaaa gggcttgcac cgggggcaca ccaagctcgc attccccagc 550

 cccttcgggc acctgtctga gggcttctcg cacagccgct ggctccggaa 600

 ggtgaaacac ggacacttcg ggtggccagg atgggaaatg ggtccaccag 650

 gaaactggag cccacgtcct cctcgtgcag gggaggcccg ccctggcccc 700

 acggcagaat cagcttctgg tccatcggag gatccgagtg tgaatttcct 750

 gaagaacgtt ggggagagtg tggcagctgc ccttagccct ctgggcattg 800

 aagttgatat cgatgtggag cacggaggga aaagaagccg cctgaccccc 850

 gtctctccag agagttccag cacagaggag aagagcagct cacagccaag 900

 cagctgctgc tctgatccca gcaagccggg tgggaatgtt gagggcgcca 950

 cgcagtctct ggcggagcag atgagaaaga tcgccttgga gtccgagggg 1000

 cgccctgagg aacagatgga gtcggataac tgttcaggag gagatgatga 1050

 ctggacccat ctgtcttcaa aagaagtgga cccgtctaca ggtgaactcc 1100

 agtccctaca gatgccagaa tccgaagggc caagctctct ggacccctcc 1150

 caggagggac ccacagggct gaaggaagct gccttgtacc cacatctccc 1200

 gccagaggct gacccgcggc tgattgagtc cctctcccag atgctgtcca 1250

 tgggcttctc tgatgaaggc ggctggctca ccaggctcct gcagaccaag 1300

 aactatgaca tcggagcggc tctggacacc atccagtatt caaagcatcc 1350

 cccgccgttg tgaccacttt tgcccacctc ttctgcgtgc ccctcttctg 1400

 tctcatagtt gtgttaagct tgcgtagaat tgcaggtctc tgtacaggcc 1450

 agtttctctg ccttcttcca ggatcagggg ttagggtgca agaagccatt 1500

 tagggcagca aaacaagtga catgaaggga gggtccctgt gtgtgtgtgt 1550

 gtgctgatgt ttcctgggtg ccctggctcc ttgcagcagg gctgggcctg 1600

 cgagacccaa ggctcactgc agcgcgctcc tgacccctcc ctgcaggggc 1650

 tacgttagca gcccagcaca tagcttgcct aatggctttc actttctctt 1700

 ttgttttaaa tgactcatag gtccctgaca tttagttgat tattttctgc 1750

 tacagacctg gtacactctg attttagata aagtaagcct aggtgttgtc 1800

 agcaggcagg ctggggaggc cagtgttgtg ggcttcctgc tgggactgag 1850

 aaggctcacg aagggcatcc gcaatgttgg tttcactgag agctgcctcc 1900

 tggtctcttc accactgtag ttctctcatt tccaaaccat cagctgcttt 1950

 taaaataaga tctctttgta gccatcctgt taaatttgta aacaatctaa 2000

 ttaaatggca tcagcacttt aaccaatgac gtttgcatag agagaaatga 2050

 ttgacagtaa gtttattgtt aatggttctt acagagtatc tttaaaagtg 2100

 ccttagggga accctgtccc tcctaacaag tgtatctcga ttaataacct 2150

 gccagtccca gatcacacat catcatcgaa gtcttcccca gttataaaga 2200

 ggtcacatag tcgtgtgggt cgaggattct gtgcctccag gaccaggggc 2250

 ccaccctctg cccagggagt ccttgcgtcc catgaggtct tcccgcaagg 2300

 cctctcagac ccagatgtga cggggtgtgt ggcccgagga agctggacag 2350

 cggcagtggg cctgctgagg ccttctcttg aggcctgtgc tctgggggtc 2400

 ccttgcttag cctgtgctgg accagctggc ctggggtccc tctgaagaga 2450

 ccttggctgc tcactgtcca catgtgaact ttttctaggt ggcaggacaa 2500

 atcgcgccca tttagaggat gtggctgtaa cctgctggat gggactccat 2550

 agctccttcc caggacccct cagctccccg gcactgcagt ctgcagagtt 2600

 ctcctggagg caggggctgc tgccttgttt caccttccat gtcaggccag 2650

 cctgtccctg aaagagaaga tggccatgcc ctccatttgt aagaacaatg 2700

 ccagggccca ggaggaccgc ctgccctgcc tgggccttgg ctgggcctct 2750

 ggttctgaca ctttctgctg gaagctgtca ggctgggaca ggctttgatt 2800

 ttgagggtta gcaagacaaa gcaaataaat gccttccacc tcaccgcaaa 2850

 aaaaaaaaaa aaaaaaaaaa 2870

<210> 336
<211> 440
<212> PRT
<213> Homo sapien

<400> 336
 Met Ala Ser Leu Thr Val Lys Ala Tyr Leu Leu Gly Lys Glu Asp
   1               5                  10                  15

 Ala Ala Arg Glu Ile Arg Arg Phe Ser Phe Cys Cys Ser Pro Glu
                  20                  25                  30

 Pro Glu Ala Glu Ala Glu Ala Ala Ala Gly Pro Gly Pro Cys Glu
                  35                  40                  45

 Arg Leu Leu Ser Arg Val Ala Ala Leu Phe Pro Ala Leu Arg Pro
                  50                  55                  60

 Gly Gly Phe Gln Ala His Tyr Arg Asp Glu Asp Gly Asp Leu Val
                  65                  70                  75

 Ala Phe Ser Ser Asp Glu Glu Leu Thr Met Ala Met Ser Tyr Val
                  80                  85                  90

 Lys Asp Asp Ile Phe Arg Ile Tyr Ile Lys Glu Lys Lys Glu Cys
                  95                 100                 105

 Arg Arg Asp His Arg Pro Pro Cys Ala Gln Glu Ala Pro Arg Asn
                 110                 115                 120

 Met Val His Pro Asn Val Ile Cys Asp Gly Cys Asn Gly Pro Val
                 125                 130                 135

 Val Gly Thr Arg Tyr Lys Cys Ser Val Cys Pro Asp Tyr Asp Leu
                 140                 145                 150

 Cys Ser Val Cys Glu Gly Lys Gly Leu His Arg Gly His Thr Lys
                 155                 160                 165

 Leu Ala Phe Pro Ser Pro Phe Gly His Leu Ser Glu Gly Phe Ser
                 170                 175                 180

 His Ser Arg Trp Leu Arg Lys Val Lys His Gly His Phe Gly Trp
                 185                 190                 195

 Pro Gly Trp Glu Met Gly Pro Pro Gly Asn Trp Ser Pro Arg Pro
                 200                 205                 210

 Pro Arg Ala Gly Glu Ala Arg Pro Gly Pro Thr Ala Glu Ser Ala
                 215                 220                 225

 Ser Gly Pro Ser Glu Asp Pro Ser Val Asn Phe Leu Lys Asn Val
                 230                 235                 240

 Gly Glu Ser Val Ala Ala Ala Leu Ser Pro Leu Gly Ile Glu Val
                 245                 250                 255

 Asp Ile Asp Val Glu His Gly Gly Lys Arg Ser Arg Leu Thr Pro
                 260                 265                 270

 Val Ser Pro Glu Ser Ser Ser Thr Glu Glu Lys Ser Ser Ser Gln
                 275                 280                 285

 Pro Ser Ser Cys Cys Ser Asp Pro Ser Lys Pro Gly Gly Asn Val
                 290                 295                 300

 Glu Gly Ala Thr Gln Ser Leu Ala Glu Gln Met Arg Lys Ile Ala
                 305                 310                 315

 Leu Glu Ser Glu Gly Arg Pro Glu Glu Gln Met Glu Ser Asp Asn
                 320                 325                 330

 Cys Ser Gly Gly Asp Asp Asp Trp Thr His Leu Ser Ser Lys Glu
                 335                 340                 345

 Val Asp Pro Ser Thr Gly Glu Leu Gln Ser Leu Gln Met Pro Glu
                 350                 355                 360

 Ser Glu Gly Pro Ser Ser Leu Asp Pro Ser Gln Glu Gly Pro Thr
                 365                 370                 375

 Gly Leu Lys Glu Ala Ala Leu Tyr Pro His Leu Pro Pro Glu Ala
                 380                 385                 390

 Asp Pro Arg Leu Ile Glu Ser Leu Ser Gln Met Leu Ser Met Gly
                 395                 400                 405

 Phe Ser Asp Glu Gly Gly Trp Leu Thr Arg Leu Leu Gln Thr Lys
                 410                 415                 420

 Asn Tyr Asp Ile Gly Ala Ala Leu Asp Thr Ile Gln Tyr Ser Lys
                 425                 430                 435

 His Pro Pro Pro Leu
                 440

<210> 337
<211> 1797
<212> DNA
<213> Homo sapien

<400> 337
 ccagcaggga gctgggagct gggggaaacg acgccaggaa agctatcgcg 50

 ccagagaggg cgacgggggc tcgggaagcc tgacagggct tttgcgcaca 100

 gctgccggct ggctgctacc cgcccgcgcc agcccccgag aacgcgcgac 150

 caggcaccca gtccggtcac cgcagcggag agctcgccgc tcgctgcagc 200

 gaggcccgga gcggccccgc agggaccctc cccagaccgc ctgggccgcc 250

 cggatgtgca ctaaaatgga acagcccttc taccacgacg actcatacac 300

 agctacggga tacggccggg cccctggtgg cctctctcta cacgactaca 350

 aactcctgaa accgagcctg gcggtcaacc tggccgaccc ctaccggagt 400

 ctcaaagcgc ctggggctcg cggacccggc ccagagggcg gcggtggcgg 450

 cagctacttt tctggtcagg gctcggacac cggcgcgtct ctcaagctcg 500

 cctcttcgga gctggaacgc ctgattgtcc ccaacagcaa cggcgtgatc 550

 acgacgacgc ctacaccccc gggacagtac ttttaccccc gcgggggtgg 600

 cagcggtgga ggtgcagggg gcgcaggggg cggcgtcacc gaggagcagg 650

 agggcttcgc cgacggcttt gtcaaagccc tggacgatct gcacaagatg 700

 aaccacgtga caccccccaa cgtgtccctg ggcgctaccg gggggccccc 750

 ggctgggccc gggggcgtct acgccggccc ggagccacct cccgtttaca 800

 ccaacctcag cagctactcc ccagcctctg cgtcctcggg aggcgccggg 850

 gctgccgtcg ggaccgggag ctcgtacccg acgaccacca tcagctacct 900

 cccacacgcg ccgcccttcg ccggtggcca cccggcgcag ctgggcttgg 950

 gccgcggcgc ctccaccttc aaggaggaac cgcagaccgt gccggaggcg 1000

 cgcagccggg acgccacgcc gccggtgtcc cccatcaaca tggaagacca 1050

 agagcgcatc aaagtggagc gcaagcggct gcggaaccgg ctggcggcca 1100

 ccaagtgccg gaagcggaag ctggagcgca tcgcgcgcct ggaggacaag 1150

 gtgaagacgc tcaaggccga gaacgcgggg ctgtcgagta ccgccggcct 1200

 cctccgggag caggtggccc agctcaaaca gaaggtcatg acccacgtca 1250

 gcaacggctg tcagctgctg cttggggtca agggacacgc cttctgaacg 1300

 tcccctgccc ctttacggac accccctcgc ttggacggct gggcacacgc 1350

 ctcccactgg ggtccaggga gcaggcggtg ggcacccacc ctgggaccta 1400

 ggggcgccgc aaaccacact ggactccggc ccccctaccc tgcgcccagt 1450

 ccttccacct cgacgtttac aagccccccc ttccactttt ttttgtatgt 1500

 tttttttctg ctggaaacag actcgattca tattgaatat aatatatttg 1550

 tgtatttaac agggagggga agagggggcg atcgcggcgg agctggcccc 1600

 gccgcctggt actcaagccc gcggggacat tgggaagggg acccccgccc 1650

 cctgccctcc cctctctgca ccgtactgtg gaaaagaaac acgcacttag 1700

 tctctaaaga gtttatttta agacgtgttt gtgtttgtgt gtgtttgttc 1750

 tttttattga atctatttaa gtaaaaaaaa aattggttct ttattaa 1797

<210> 338
<211> 347
<212> PRT
<213> Homo sapien

<400> 338
 Met Cys Thr Lys Met Glu Gln Pro Phe Tyr His Asp Asp Ser Tyr
   1               5                  10                  15

 Thr Ala Thr Gly Tyr Gly Arg Ala Pro Gly Gly Leu Ser Leu His
                  20                  25                  30

 Asp Tyr Lys Leu Leu Lys Pro Ser Leu Ala Val Asn Leu Ala Asp
                  35                  40                  45

 Pro Tyr Arg Ser Leu Lys Ala Pro Gly Ala Arg Gly Pro Gly Pro
                  50                  55                  60

 Glu Gly Gly Gly Gly Gly Ser Tyr Phe Ser Gly Gln Gly Ser Asp
                  65                  70                  75

 Thr Gly Ala Ser Leu Lys Leu Ala Ser Ser Glu Leu Glu Arg Leu
                  80                  85                  90

 Ile Val Pro Asn Ser Asn Gly Val Ile Thr Thr Thr Pro Thr Pro
                  95                 100                 105

 Pro Gly Gln Tyr Phe Tyr Pro Arg Gly Gly Gly Ser Gly Gly Gly
                 110                 115                 120

 Ala Gly Gly Ala Gly Gly Gly Val Thr Glu Glu Gln Glu Gly Phe
                 125                 130                 135

 Ala Asp Gly Phe Val Lys Ala Leu Asp Asp Leu His Lys Met Asn
                 140                 145                 150

 His Val Thr Pro Pro Asn Val Ser Leu Gly Ala Thr Gly Gly Pro
                 155                 160                 165

 Pro Ala Gly Pro Gly Gly Val Tyr Ala Gly Pro Glu Pro Pro Pro
                 170                 175                 180

 Val Tyr Thr Asn Leu Ser Ser Tyr Ser Pro Ala Ser Ala Ser Ser
                 185                 190                 195

 Gly Gly Ala Gly Ala Ala Val Gly Thr Gly Ser Ser Tyr Pro Thr
                 200                 205                 210

 Thr Thr Ile Ser Tyr Leu Pro His Ala Pro Pro Phe Ala Gly Gly
                 215                 220                 225

 His Pro Ala Gln Leu Gly Leu Gly Arg Gly Ala Ser Thr Phe Lys
                 230                 235                 240

 Glu Glu Pro Gln Thr Val Pro Glu Ala Arg Ser Arg Asp Ala Thr
                 245                 250                 255

 Pro Pro Val Ser Pro Ile Asn Met Glu Asp Gln Glu Arg Ile Lys
                 260                 265                 270

 Val Glu Arg Lys Arg Leu Arg Asn Arg Leu Ala Ala Thr Lys Cys
                 275                 280                 285

 Arg Lys Arg Lys Leu Glu Arg Ile Ala Arg Leu Glu Asp Lys Val
                 290                 295                 300

 Lys Thr Leu Lys Ala Glu Asn Ala Gly Leu Ser Ser Thr Ala Gly
                 305                 310                 315

 Leu Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Met Thr
                 320                 325                 330

 His Val Ser Asn Gly Cys Gln Leu Leu Leu Gly Val Lys Gly His
                 335                 340                 345

 Ala Phe


<210> 339
<211> 2795
<212> DNA
<213> Homo sapien

<400> 339
 atcagcgagg gattcacggc gaaatgagac tgttcgtgag tgatggcgtc 50

 ccgggttgct tgccggtgct ggccgccgcc gggagagccc ggggcagagc 100

 agaggtgctc atcagcactg taggcccgga agattgtgtg gtcccgttcc 150

 tgacccggcc taaggtccct gtcttgcagc tggatagcgg caactacctc 200

 ttctccacta gtgcaatctg ccgatatttt tttttgttat ctggctggga 250

 gcaagatgac ctcactaacc agtggctgga atgggaagcg acagagctgc 300

 agccagcttt gtctgctgcc ctgtactatt tagtggtcca aggcaagaag 350

 ggggaagatg ttcttggttc agtgcggaga gccctgactc acattgacca 400

 cagcttgagt cgtcagaact gtcctttcct ggctggggag acagaatctc 450

 tagccgacat tgttttgtgg ggagccctat acccattact gcaagatccc 500

 gcctacctcc ctgaggagct gagtgccctg cacagctggt tccagacact 550

 gagtacccag gaaccatgtc agcgagctgc agagactgta ctgaaacagc 600

 aaggtgtcct ggctctccgg ccttacctcc aaaagcagcc ccagcccagc 650

 cccgctgagg gaagggctgt caccaatgag cctgaggagg aggagctggc 700

 taccctatct gaggaggaga ttgctatggc tgttactgct tgggagaagg 750

 gcctagaaag tttgcccccg ctgcggcccc agcagaatcc agtgttgcct 800

 gtggctggag aaaggaatgt gctcatcacc agtgccctcc cttacgtcaa 850

 caatgtcccc caccttggga acatcattgg ttgtgtgctc agtgccgatg 900

 tctttgccag gtactctcgc ctccgccagt ggaacaccct ctatctgtgt 950

 gggacagatg agtatggtac agcaacagag accaaggctc tggaggaggg 1000

 actaaccccc caggagatct gcgacaagta ccacatcatc catgctgaca 1050

 tctaccgctg gtttaacatt tcgtttgata tttttggtcg caccaccact 1100

 ccacagcaga ccaaaatcac ccaggacatt ttccagcagt tgctgaaacg 1150

 aggttttgtg ctgcaagata ctgtggagca actgcgatgt gagcactgtg 1200

 ctcgcttcct ggctgaccgc ttcgtggagg gcgtgtgtcc cttctgtggc 1250

 tatgaggagg ctcggggtga ccagtgtgac aagtgtggca agctcatcaa 1300

 tgctgtcgag cttaagaagc ctcagtgtaa agtctgccga tcatgccctg 1350

 tggtgcagtc gagccagcac ctgtttctgg acctgcctaa gctggagaag 1400

 cgactggagg agtggttggg gaggacattg cctggcagtg actggacacc 1450

 caatgcccag tttatcaccc gttcttggct tcgggatggc ctcaagccac 1500

 gctgcataac ccgagacctc aaatggggaa cccctgtacc cttagaaggt 1550

 tttgaagaca aggtattcta tgtctggttt gatgccacta ttggctatct 1600

 gtccatcaca gccaactaca cagaccagtg ggagagatgg tggaagaacc 1650

 cagagcaagt ggacctgtat cagttcatgg ccaaagacaa tgttcctttc 1700

 catagcttag tctttccttg ctcagcccta ggagctgagg ataactatac 1750

 cttggtcagc cacctcattg ctacagagta cctgaactat gaggatggga 1800

 aattctctaa gagccgcggt gtgggagtgt ttggggacat ggcccaggac 1850

 acggggatcc ctgctgacat ctggcgcttc tatctgctgt acattcggcc 1900

 tgagggccag gacagtgctt tctcctggac ggacctgctg ctgaagaata 1950

 attctgagct gcttaacaac ctgggcaact tcatcaacag agctgggatg 2000

 tttgtgtcta agttctttgg gggctatgtg cctgagatgg tgctcacccc 2050

 tgatgatcag cgcctgctgg cccatgtcac cctggagctc cagcactatc 2100

 accagctact tgagaaggtt cggatccggg atgccttgcg cagtatcctc 2150

 accatatctc gacatggcaa ccaatatatt caggtgaatg agccctggaa 2200

 gcggattaaa ggcagtgagg ctgacaggca acgggcagga acagtgactg 2250

 gcttggcagt gaatatagct gccttgctct ctgtcatgct tcagccttac 2300

 atgcccacgg ttagtgccac aatccaggcc cagctgcagc tcccacctcc 2350

 agcctgcagt atcctgctga caaacttcct gtgtacctta ccagcaggac 2400

 accagattgg cacagtcagt cccttgttcc aaaaattgga aaatgaccag 2450

 attgaaagtt taaggcagcg ctttggaggg ggccaggcaa aaacgtcccc 2500

 gaagccagca gttgtagaga ctgttacaac agccaagcca cagcagatac 2550

 aagcgctgat ggatgaagtg acaaaacaag gaaacattgt ccgagaactg 2600

 aaagcacaaa aggcagacaa gaacgaggtt gctgcggagg tggcgaaact 2650

 cttggatcta aagaaacagt tggctgtagc tgaggggaaa ccccctgaag 2700

 cccctaaagg caagaagaaa aagtaaaaga ccttggctca tagaaagtca 2750

 ctttaataga tagggacagt aataaataaa tgtacaatct ctata 2795

<210> 340
<211> 900
<212> PRT
<213> Homo sapien

<400> 340
 Met Arg Leu Phe Val Ser Asp Gly Val Pro Gly Cys Leu Pro Val
   1               5                  10                  15

 Leu Ala Ala Ala Gly Arg Ala Arg Gly Arg Ala Glu Val Leu Ile
                  20                  25                  30

 Ser Thr Val Gly Pro Glu Asp Cys Val Val Pro Phe Leu Thr Arg
                  35                  40                  45

 Pro Lys Val Pro Val Leu Gln Leu Asp Ser Gly Asn Tyr Leu Phe
                  50                  55                  60

 Ser Thr Ser Ala Ile Cys Arg Tyr Phe Phe Leu Leu Ser Gly Trp
                  65                  70                  75

 Glu Gln Asp Asp Leu Thr Asn Gln Trp Leu Glu Trp Glu Ala Thr
                  80                  85                  90

 Glu Leu Gln Pro Ala Leu Ser Ala Ala Leu Tyr Tyr Leu Val Val
                  95                 100                 105

 Gln Gly Lys Lys Gly Glu Asp Val Leu Gly Ser Val Arg Arg Ala
                 110                 115                 120

 Leu Thr His Ile Asp His Ser Leu Ser Arg Gln Asn Cys Pro Phe
                 125                 130                 135

 Leu Ala Gly Glu Thr Glu Ser Leu Ala Asp Ile Val Leu Trp Gly
                 140                 145                 150

 Ala Leu Tyr Pro Leu Leu Gln Asp Pro Ala Tyr Leu Pro Glu Glu
                 155                 160                 165

 Leu Ser Ala Leu His Ser Trp Phe Gln Thr Leu Ser Thr Gln Glu
                 170                 175                 180

 Pro Cys Gln Arg Ala Ala Glu Thr Val Leu Lys Gln Gln Gly Val
                 185                 190                 195

 Leu Ala Leu Arg Pro Tyr Leu Gln Lys Gln Pro Gln Pro Ser Pro
                 200                 205                 210

 Ala Glu Gly Arg Ala Val Thr Asn Glu Pro Glu Glu Glu Glu Leu
                 215                 220                 225

 Ala Thr Leu Ser Glu Glu Glu Ile Ala Met Ala Val Thr Ala Trp
                 230                 235                 240

 Glu Lys Gly Leu Glu Ser Leu Pro Pro Leu Arg Pro Gln Gln Asn
                 245                 250                 255

 Pro Val Leu Pro Val Ala Gly Glu Arg Asn Val Leu Ile Thr Ser
                 260                 265                 270

 Ala Leu Pro Tyr Val Asn Asn Val Pro His Leu Gly Asn Ile Ile
                 275                 280                 285

 Gly Cys Val Leu Ser Ala Asp Val Phe Ala Arg Tyr Ser Arg Leu
                 290                 295                 300

 Arg Gln Trp Asn Thr Leu Tyr Leu Cys Gly Thr Asp Glu Tyr Gly
                 305                 310                 315

 Thr Ala Thr Glu Thr Lys Ala Leu Glu Glu Gly Leu Thr Pro Gln
                 320                 325                 330

 Glu Ile Cys Asp Lys Tyr His Ile Ile His Ala Asp Ile Tyr Arg
                 335                 340                 345

 Trp Phe Asn Ile Ser Phe Asp Ile Phe Gly Arg Thr Thr Thr Pro
                 350                 355                 360

 Gln Gln Thr Lys Ile Thr Gln Asp Ile Phe Gln Gln Leu Leu Lys
                 365                 370                 375

 Arg Gly Phe Val Leu Gln Asp Thr Val Glu Gln Leu Arg Cys Glu
                 380                 385                 390

 His Cys Ala Arg Phe Leu Ala Asp Arg Phe Val Glu Gly Val Cys
                 395                 400                 405

 Pro Phe Cys Gly Tyr Glu Glu Ala Arg Gly Asp Gln Cys Asp Lys
                 410                 415                 420

 Cys Gly Lys Leu Ile Asn Ala Val Glu Leu Lys Lys Pro Gln Cys
                 425                 430                 435

 Lys Val Cys Arg Ser Cys Pro Val Val Gln Ser Ser Gln His Leu
                 440                 445                 450

 Phe Leu Asp Leu Pro Lys Leu Glu Lys Arg Leu Glu Glu Trp Leu
                 455                 460                 465

 Gly Arg Thr Leu Pro Gly Ser Asp Trp Thr Pro Asn Ala Gln Phe
                 470                 475                 480

 Ile Thr Arg Ser Trp Leu Arg Asp Gly Leu Lys Pro Arg Cys Ile
                 485                 490                 495

 Thr Arg Asp Leu Lys Trp Gly Thr Pro Val Pro Leu Glu Gly Phe
                 500                 505                 510

 Glu Asp Lys Val Phe Tyr Val Trp Phe Asp Ala Thr Ile Gly Tyr
                 515                 520                 525

 Leu Ser Ile Thr Ala Asn Tyr Thr Asp Gln Trp Glu Arg Trp Trp
                 530                 535                 540

 Lys Asn Pro Glu Gln Val Asp Leu Tyr Gln Phe Met Ala Lys Asp
                 545                 550                 555

 Asn Val Pro Phe His Ser Leu Val Phe Pro Cys Ser Ala Leu Gly
                 560                 565                 570

 Ala Glu Asp Asn Tyr Thr Leu Val Ser His Leu Ile Ala Thr Glu
                 575                 580                 585

 Tyr Leu Asn Tyr Glu Asp Gly Lys Phe Ser Lys Ser Arg Gly Val
                 590                 595                 600

 Gly Val Phe Gly Asp Met Ala Gln Asp Thr Gly Ile Pro Ala Asp
                 605                 610                 615

 Ile Trp Arg Phe Tyr Leu Leu Tyr Ile Arg Pro Glu Gly Gln Asp
                 620                 625                 630

 Ser Ala Phe Ser Trp Thr Asp Leu Leu Leu Lys Asn Asn Ser Glu
                 635                 640                 645

 Leu Leu Asn Asn Leu Gly Asn Phe Ile Asn Arg Ala Gly Met Phe
                 650                 655                 660

 Val Ser Lys Phe Phe Gly Gly Tyr Val Pro Glu Met Val Leu Thr
                 665                 670                 675

 Pro Asp Asp Gln Arg Leu Leu Ala His Val Thr Leu Glu Leu Gln
                 680                 685                 690

 His Tyr His Gln Leu Leu Glu Lys Val Arg Ile Arg Asp Ala Leu
                 695                 700                 705

 Arg Ser Ile Leu Thr Ile Ser Arg His Gly Asn Gln Tyr Ile Gln
                 710                 715                 720

 Val Asn Glu Pro Trp Lys Arg Ile Lys Gly Ser Glu Ala Asp Arg
                 725                 730                 735

 Gln Arg Ala Gly Thr Val Thr Gly Leu Ala Val Asn Ile Ala Ala
                 740                 745                 750

 Leu Leu Ser Val Met Leu Gln Pro Tyr Met Pro Thr Val Ser Ala
                 755                 760                 765

 Thr Ile Gln Ala Gln Leu Gln Leu Pro Pro Pro Ala Cys Ser Ile
                 770                 775                 780

 Leu Leu Thr Asn Phe Leu Cys Thr Leu Pro Ala Gly His Gln Ile
                 785                 790                 795

 Gly Thr Val Ser Pro Leu Phe Gln Lys Leu Glu Asn Asp Gln Ile
                 800                 805                 810

 Glu Ser Leu Arg Gln Arg Phe Gly Gly Gly Gln Ala Lys Thr Ser
                 815                 820                 825

 Pro Lys Pro Ala Val Val Glu Thr Val Thr Thr Ala Lys Pro Gln
                 830                 835                 840

 Gln Ile Gln Ala Leu Met Asp Glu Val Thr Lys Gln Gly Asn Ile
                 845                 850                 855

 Val Arg Glu Leu Lys Ala Gln Lys Ala Asp Lys Asn Glu Val Ala
                 860                 865                 870

 Ala Glu Val Ala Lys Leu Leu Asp Leu Lys Lys Gln Leu Ala Val
                 875                 880                 885

 Ala Glu Gly Lys Pro Pro Glu Ala Pro Lys Gly Lys Lys Lys Lys
                 890                 895                 900

<210> 341
<211> 3117
<212> DNA
<213> Homo sapien

<400> 341
 attcgaaccc cgtcgcgccc ctttgtgcgt cacgggtggc gggcgcggga 50

 aggggatttg gattgttgcg cctctgctct gaagaaagtg ctgtctggct 100

 ccaactccag ttctttcccc tgagcagcgc ctggaaccta acccttccca 150

 ctctgtcacc ttctcgatcc cgccggcgct ttagagccgc agtccagtct 200

 tggatccttc agagcctcag ccactagctg cgatgcatgt gatcaagcga 250

 gatggccgcc aagaacgagt catgtttgac aaaattacat ctcgaatcca 300

 gaagctttgt tatggactca atatggattt tgttgatcct gctcagatca 350

 ccatgaaagt aatccaaggc ttgtacagtg gggtcaccac agtggaacta 400

 gatactttgg ctgctgaaac agctgcaacc ttgactacta agcaccctga 450

 ctatgctatc ctggcagcca ggatcgctgt ctctaacttg cacaaagaaa 500

 caaagaaagt gttcagtgat gtgatggaag acctctataa ctacataaat 550

 ccacataatg gcaaacactc tcccatggtg gccaagtcaa cattggatat 600

 tgttctggcc aataaagatc gcctgaattc tgctattatc tatgaccgag 650

 atttctctta caattacttc ggctttaaga cgctagagcg gtcttatttg 700

 ttgaagatca atggaaaagt ggctgaaaga ccacaacata tgttgatgag 750

 agtatctgtt gggatccaca aagaagacat tgatgcagca attgaaacat 800

 ataatcttct ttctgagagg tggtttactc atgcttcgcc cactctcttc 850

 aatgctggta ccaaccgccc acaactttct agctgttttc ttctgagtat 900

 gaaagatgac agcattgaag gcatttatga cactctaaag caatgtgcat 950

 tgatttctaa gtctgctgga ggaattggtg ttgctgtgag ttgtattcgg 1000

 gctactggca gctacattgc tgggactaat ggcaattcca atggccttgt 1050

 accgatgctg agagtatata acaacacagc tagatatgtg gatcaaggtg 1100

 ggaacaagcg tcctggggca tttgctattt acctggagcc ttggcattta 1150

 gacatctttg aattccttga tttaaagaag aacacaggaa aggaagagca 1200

 gcgtgccaga gatcttttct ttgctctttg gattccggat ctcttcatga 1250

 aacgagtgga gactaatcag gactggtctt tgatgtgtcc aaatgagtgt 1300

 cctggtctgg atgaggtttg gggagaggaa tttgagaaac tatatgcaag 1350

 ttatgagaaa caaggtcgtg tccgcaaagt tgtaaaagct cagcagcttt 1400

 ggtatgccat cattgagtct cagacggaaa caggcacccc gtatatgctc 1450

 tacaaagatt cctgtaatcg aaagagcaac cagcagaacc tgggaaccat 1500

 caaatgcagc aacctgtgca cagaaatagt ggagtacacc agcaaagatg 1550

 aggttgctgt ttgtaatttg gcttccctgg ccctgaatat gtatgtcaca 1600

 tcagaacaca catacgactt taagaagttg gctgaagtca ctaaagtcgt 1650

 tgtccgaaac ttgaataaaa ttattgatat aaactactat cctgtaccag 1700

 aggcatgcct atcaaataaa cgccatcgcc ccattggaat tggggtacaa 1750

 ggtctggcag atgcttttat cctgatgaga tacccttttg agagtgcaga 1800

 agcccagtta ctgaataagc agatctttga aactatttat tatggtgctc 1850

 tggaagccag ctgtgacctt gccaaggagc agggcccata cgaaacctat 1900

 gagggctctc cagttagcaa aggaattctt cagtatgata tgtggaatgt 1950

 tactcctaca gacctatggg actggaaggt tctcaaggag aagattgcaa 2000

 agtatggtat aagaaacagt ttacttattg ccccgatgcc tacagcttcc 2050

 actgctcaga tcctggggaa taatgagtcc attgaacctt acaccagcaa 2100

 catctatact cgcagagtct tgtcaggaga atttcagatt gtaaatcctc 2150

 acttattgaa agatcttacc gagcggggcc tatggcatga agagatgaaa 2200

 aaccagatta ttgcatgcaa tggctctatt cagagcatac cagaaattcc 2250

 tgatgacctg aagcaacttt ataaaactgt gtgggaaatc tctcagaaaa 2300

 ctgttctcaa gatggcagct gagagaggtg ctttcattga tcaaagccaa 2350

 tctttgaaca tccacattgc tgagcctaac tatggcaaac tcactagtat 2400

 gcacttctac ggctggaagc agggtttgaa gactgggatg tattatttaa 2450

 ggacaagacc agcagctaat ccaatccagt tcactctaaa taaggagaag 2500

 ctaaaagata aagaaaaggt atcaaaagag gaagaagaga aggagaggaa 2550

 cacagcagcc atggtgtgct ctttggagaa tagagatgaa tgtctgatgt 2600

 gtggatcctg aggaaagact tggaagagac cagcatgtct tcagtagcca 2650

 aactacttct tgagcataga taggtatagt gggtttgctt gaggtggtaa 2700

 ggctttgctg gaccctgttg caggcaaaag gagtaattga tttaaagtac 2750

 tgttaatgat gttaatgatt tttttttaaa ctcatatatt gggattttca 2800

 ccaaaataat gcttttgaaa aaaagaaaaa aaaaacggat atattgagaa 2850

 tcaaagtaga agttttagga atgcaaaata agtcatcttg catacaggga 2900

 gtggttaagt aaggtttcat cacccattta gcatgctttt ctgaagactt 2950

 cagttttgtt aaggagattt agttttactg ctttgactgg tgggtctcta 3000

 gaagcaaaac tgagtgataa ctcatgagaa gtactgatag gacctttatc 3050

 tggatatggt cctataggtt attctgaaat aaagataaac atttctaagt 3100

 gaaaaaaaaa aaaaaaa 3117

<210> 342
<211> 792
<212> PRT
<213> Homo sapien

<400> 342
 Met His Val Ile Lys Arg Asp Gly Arg Gln Glu Arg Val Met Phe
   1               5                  10                  15

 Asp Lys Ile Thr Ser Arg Ile Gln Lys Leu Cys Tyr Gly Leu Asn
                  20                  25                  30

 Met Asp Phe Val Asp Pro Ala Gln Ile Thr Met Lys Val Ile Gln
                  35                  40                  45

 Gly Leu Tyr Ser Gly Val Thr Thr Val Glu Leu Asp Thr Leu Ala
                  50                  55                  60

 Ala Glu Thr Ala Ala Thr Leu Thr Thr Lys His Pro Asp Tyr Ala
                  65                  70                  75

 Ile Leu Ala Ala Arg Ile Ala Val Ser Asn Leu His Lys Glu Thr
                  80                  85                  90

 Lys Lys Val Phe Ser Asp Val Met Glu Asp Leu Tyr Asn Tyr Ile
                  95                 100                 105

 Asn Pro His Asn Gly Lys His Ser Pro Met Val Ala Lys Ser Thr
                 110                 115                 120

 Leu Asp Ile Val Leu Ala Asn Lys Asp Arg Leu Asn Ser Ala Ile
                 125                 130                 135

 Ile Tyr Asp Arg Asp Phe Ser Tyr Asn Tyr Phe Gly Phe Lys Thr
                 140                 145                 150

 Leu Glu Arg Ser Tyr Leu Leu Lys Ile Asn Gly Lys Val Ala Glu
                 155                 160                 165

 Arg Pro Gln His Met Leu Met Arg Val Ser Val Gly Ile His Lys
                 170                 175                 180

 Glu Asp Ile Asp Ala Ala Ile Glu Thr Tyr Asn Leu Leu Ser Glu
                 185                 190                 195

 Arg Trp Phe Thr His Ala Ser Pro Thr Leu Phe Asn Ala Gly Thr
                 200                 205                 210

 Asn Arg Pro Gln Leu Ser Ser Cys Phe Leu Leu Ser Met Lys Asp
                 215                 220                 225

 Asp Ser Ile Glu Gly Ile Tyr Asp Thr Leu Lys Gln Cys Ala Leu
                 230                 235                 240

 Ile Ser Lys Ser Ala Gly Gly Ile Gly Val Ala Val Ser Cys Ile
                 245                 250                 255

 Arg Ala Thr Gly Ser Tyr Ile Ala Gly Thr Asn Gly Asn Ser Asn
                 260                 265                 270

 Gly Leu Val Pro Met Leu Arg Val Tyr Asn Asn Thr Ala Arg Tyr
                 275                 280                 285

 Val Asp Gln Gly Gly Asn Lys Arg Pro Gly Ala Phe Ala Ile Tyr
                 290                 295                 300

 Leu Glu Pro Trp His Leu Asp Ile Phe Glu Phe Leu Asp Leu Lys
                 305                 310                 315

 Lys Asn Thr Gly Lys Glu Glu Gln Arg Ala Arg Asp Leu Phe Phe
                 320                 325                 330

 Ala Leu Trp Ile Pro Asp Leu Phe Met Lys Arg Val Glu Thr Asn
                 335                 340                 345

 Gln Asp Trp Ser Leu Met Cys Pro Asn Glu Cys Pro Gly Leu Asp
                 350                 355                 360

 Glu Val Trp Gly Glu Glu Phe Glu Lys Leu Tyr Ala Ser Tyr Glu
                 365                 370                 375

 Lys Gln Gly Arg Val Arg Lys Val Val Lys Ala Gln Gln Leu Trp
                 380                 385                 390

 Tyr Ala Ile Ile Glu Ser Gln Thr Glu Thr Gly Thr Pro Tyr Met
                 395                 400                 405

 Leu Tyr Lys Asp Ser Cys Asn Arg Lys Ser Asn Gln Gln Asn Leu
                 410                 415                 420

 Gly Thr Ile Lys Cys Ser Asn Leu Cys Thr Glu Ile Val Glu Tyr
                 425                 430                 435

 Thr Ser Lys Asp Glu Val Ala Val Cys Asn Leu Ala Ser Leu Ala
                 440                 445                 450

 Leu Asn Met Tyr Val Thr Ser Glu His Thr Tyr Asp Phe Lys Lys
                 455                 460                 465

 Leu Ala Glu Val Thr Lys Val Val Val Arg Asn Leu Asn Lys Ile
                 470                 475                 480

 Ile Asp Ile Asn Tyr Tyr Pro Val Pro Glu Ala Cys Leu Ser Asn
                 485                 490                 495

 Lys Arg His Arg Pro Ile Gly Ile Gly Val Gln Gly Leu Ala Asp
                 500                 505                 510

 Ala Phe Ile Leu Met Arg Tyr Pro Phe Glu Ser Ala Glu Ala Gln
                 515                 520                 525

 Leu Leu Asn Lys Gln Ile Phe Glu Thr Ile Tyr Tyr Gly Ala Leu
                 530                 535                 540

 Glu Ala Ser Cys Asp Leu Ala Lys Glu Gln Gly Pro Tyr Glu Thr
                 545                 550                 555

 Tyr Glu Gly Ser Pro Val Ser Lys Gly Ile Leu Gln Tyr Asp Met
                 560                 565                 570

 Trp Asn Val Thr Pro Thr Asp Leu Trp Asp Trp Lys Val Leu Lys
                 575                 580                 585

 Glu Lys Ile Ala Lys Tyr Gly Ile Arg Asn Ser Leu Leu Ile Ala
                 590                 595                 600

 Pro Met Pro Thr Ala Ser Thr Ala Gln Ile Leu Gly Asn Asn Glu
                 605                 610                 615

 Ser Ile Glu Pro Tyr Thr Ser Asn Ile Tyr Thr Arg Arg Val Leu
                 620                 625                 630

 Ser Gly Glu Phe Gln Ile Val Asn Pro His Leu Leu Lys Asp Leu
                 635                 640                 645

 Thr Glu Arg Gly Leu Trp His Glu Glu Met Lys Asn Gln Ile Ile
                 650                 655                 660

 Ala Cys Asn Gly Ser Ile Gln Ser Ile Pro Glu Ile Pro Asp Asp
                 665                 670                 675

 Leu Lys Gln Leu Tyr Lys Thr Val Trp Glu Ile Ser Gln Lys Thr
                 680                 685                 690

 Val Leu Lys Met Ala Ala Glu Arg Gly Ala Phe Ile Asp Gln Ser
                 695                 700                 705

 Gln Ser Leu Asn Ile His Ile Ala Glu Pro Asn Tyr Gly Lys Leu
                 710                 715                 720

 Thr Ser Met His Phe Tyr Gly Trp Lys Gln Gly Leu Lys Thr Gly
                 725                 730                 735

 Met Tyr Tyr Leu Arg Thr Arg Pro Ala Ala Asn Pro Ile Gln Phe
                 740                 745                 750

 Thr Leu Asn Lys Glu Lys Leu Lys Asp Lys Glu Lys Val Ser Lys
                 755                 760                 765

 Glu Glu Glu Glu Lys Glu Arg Asn Thr Ala Ala Met Val Cys Ser
                 770                 775                 780

 Leu Glu Asn Arg Asp Glu Cys Leu Met Cys Gly Ser
                 785                 790

<210> 343
<211> 3117
<212> DNA
<213> Homo sapien

<400> 343
 attcgaaccc cgtcgcgccc ctttgtgcgt cacgggtggc gggcgcggga 50

 aggggatttg gattgttgcg cctctgctct gaagaaagtg ctgtctggct 100

 ccaactccag ttctttcccc tgagcagcgc ctggaaccta acccttccca 150

 ctctgtcacc ttctcgatcc cgccggcgct ttagagccgc agtccagtct 200

 tggatccttc agagcctcag ccactagctg cgatgcatgt gatcaagcga 250

 gatggccgcc aagaacgagt catgtttgac aaaattacat ctcgaatcca 300

 gaagctttgt tatggactca atatggattt tgttgatcct gctcagatca 350

 ccatgaaagt aatccaaggc ttgtacagtg gggtcaccac agtggaacta 400

 gatactttgg ctgctgaaac agctgcaacc ttgactacta agcaccctga 450

 ctatgctatc ctggcagcca ggatcgctgt ctctaacttg cacaaagaaa 500

 caaagaaagt gttcagtgat gtgatggaag acctctataa ctacataaat 550

 ccacataatg gcaaacactc tcccatggtg gccaagtcaa cattggatat 600

 tgttctggcc aataaagatc gcctgaattc tgctattatc tatgaccgag 650

 atttctctta caattacttc ggctttaaga cgctagagcg gtcttatttg 700

 ttgaagatca atggaaaagt ggctgaaaga ccacaacata tgttgatgag 750

 agtatctgtt gggatccaca aagaagacat tgatgcagca attgaaacat 800

 ataatcttct ttctgagagg tggtttactc atgcttcgcc cactctcttc 850

 aatgctggta ccaaccgccc acaactttct agctgttttc ttctgagtat 900

 gaaagatgac agcattgaag gcatttatga cactctaaag caatgtgcat 950

 tgatttctaa gtctgctgga ggaattggtg ttgctgtgag ttgtattcgg 1000

 gctactggca gctacattgc tgggactaat ggcaattcca atggccttgt 1050

 accgatgctg agagtatata acaacacagc tagatatgtg gatcaaggtg 1100

 ggaacaagcg tcctggggca tttgctattt acctggagcc ttggcattta 1150

 gacatctttg aattccttga tttaaagaag aacacaggaa aggaagagca 1200

 gcgtgccaga gatcttttct ttgctctttg gattccggat ctcttcatga 1250

 aacgagtgga gactaatcag gactggtctt tgatgtgtcc aaatgagtgt 1300

 cctggtctgg atgaggtttg gggagaggaa tttgagaaac tatatgcaag 1350

 ttatgagaaa caaggtcgtg tccgcaaagt tgtaaaagct cagcagcttt 1400

 ggtatgccat cattgagtct cagacggaaa caggcacccc gtatatgctc 1450

 tacaaagatt cctgtaatcg aaagagcaac cagcagaacc tgggaaccat 1500

 caaatgcagc aacctgtgca cagaaatagt ggagtacacc agcaaagatg 1550

 aggttgctgt ttgtaatttg gcttccctgg ccctgaatat gtatgtcaca 1600

 tcagaacaca catacgactt taagaagttg gctgaagtca ctaaagtcgt 1650

 tgtccgaaac ttgaataaaa ttattgatat aaactactat cctgtaccag 1700

 aggcatgcct atcaaataaa cgccatcgcc ccattggaat tggggtacaa 1750

 ggtctggcag atgcttttat cctgatgaga tacccttttg agagtgcaga 1800

 agcccagtta ctgaataagc agatctttga aactatttat tatggtgctc 1850

 tggaagccag ctgtgacctt gccaaggagc agggcccata cgaaacctat 1900

 gagggctctc cagttagcaa aggaattctt cagtatgata tgtggaatgt 1950

 tactcctaca gacctatggg actggaaggt tctcaaggag aagattgcaa 2000

 agtatggtat aagaaacagt ttacttattg ccccgatgcc tacagcttcc 2050

 actgctcaga tcctggggaa taatgagtcc attgaacctt acaccagcaa 2100

 catctatact cgcagagtct tgtcaggaga atttcagatt gtaaatcctc 2150

 acttattgaa agatcttacc gagcggggcc tatggcatga agagatgaaa 2200

 aaccagatta ttgcatgcaa tggctctatt cagagcatac cagaaattcc 2250

 tgatgacctg aagcaacttt ataaaactgt gtgggaaatc tctcagaaaa 2300

 ctgttctcaa gatggcagct gagagaggtg ctttcattga tcaaagccaa 2350

 tctttgaaca tccacattgc tgagcctaac tatggcaaac tcactagtat 2400

 gcacttctac ggctggaagc agggtttgaa gactgggatg tattatttaa 2450

 ggacaagacc agcagctaat ccaatccagt tcactctaaa taaggagaag 2500

 ctaaaagata aagaaaaggt atcaaaagag gaagaagaga aggagaggaa 2550

 cacagcagcc atggtgtgct ctttggagaa tagagatgaa tgtctgatgt 2600

 gtggatcctg aggaaagact tggaagagac cagcatgtct tcagtagcca 2650

 aactacttct tgagcataga taggtatagt gggtttgctt gaggtggtaa 2700

 ggctttgctg gaccctgttg caggcaaaag gagtaattga tttaaagtac 2750

 tgttaatgat gttaatgatt tttttttaaa ctcatatatt gggattttca 2800

 ccaaaataat gcttttgaaa aaaagaaaaa aaaaacggat atattgagaa 2850

 tcaaagtaga agttttagga atgcaaaata agtcatcttg catacaggga 2900

 gtggttaagt aaggtttcat cacccattta gcatgctttt ctgaagactt 2950

 cagttttgtt aaggagattt agttttactg ctttgactgg tgggtctcta 3000

 gaagcaaaac tgagtgataa ctcatgagaa gtactgatag gacctttatc 3050

 tggatatggt cctataggtt attctgaaat aaagataaac atttctaagt 3100

 gaaaaaaaaa aaaaaaa 3117

<210> 344
<211> 792
<212> PRT
<213> Homo sapien

<400> 344
 Met His Val Ile Lys Arg Asp Gly Arg Gln Glu Arg Val Met Phe
   1               5                  10                  15

 Asp Lys Ile Thr Ser Arg Ile Gln Lys Leu Cys Tyr Gly Leu Asn
                  20                  25                  30

 Met Asp Phe Val Asp Pro Ala Gln Ile Thr Met Lys Val Ile Gln
                  35                  40                  45

 Gly Leu Tyr Ser Gly Val Thr Thr Val Glu Leu Asp Thr Leu Ala
                  50                  55                  60

 Ala Glu Thr Ala Ala Thr Leu Thr Thr Lys His Pro Asp Tyr Ala
                  65                  70                  75

 Ile Leu Ala Ala Arg Ile Ala Val Ser Asn Leu His Lys Glu Thr
                  80                  85                  90

 Lys Lys Val Phe Ser Asp Val Met Glu Asp Leu Tyr Asn Tyr Ile
                  95                 100                 105

 Asn Pro His Asn Gly Lys His Ser Pro Met Val Ala Lys Ser Thr
                 110                 115                 120

 Leu Asp Ile Val Leu Ala Asn Lys Asp Arg Leu Asn Ser Ala Ile
                 125                 130                 135

 Ile Tyr Asp Arg Asp Phe Ser Tyr Asn Tyr Phe Gly Phe Lys Thr
                 140                 145                 150

 Leu Glu Arg Ser Tyr Leu Leu Lys Ile Asn Gly Lys Val Ala Glu
                 155                 160                 165

 Arg Pro Gln His Met Leu Met Arg Val Ser Val Gly Ile His Lys
                 170                 175                 180

 Glu Asp Ile Asp Ala Ala Ile Glu Thr Tyr Asn Leu Leu Ser Glu
                 185                 190                 195

 Arg Trp Phe Thr His Ala Ser Pro Thr Leu Phe Asn Ala Gly Thr
                 200                 205                 210

 Asn Arg Pro Gln Leu Ser Ser Cys Phe Leu Leu Ser Met Lys Asp
                 215                 220                 225

 Asp Ser Ile Glu Gly Ile Tyr Asp Thr Leu Lys Gln Cys Ala Leu
                 230                 235                 240

 Ile Ser Lys Ser Ala Gly Gly Ile Gly Val Ala Val Ser Cys Ile
                 245                 250                 255

 Arg Ala Thr Gly Ser Tyr Ile Ala Gly Thr Asn Gly Asn Ser Asn
                 260                 265                 270

 Gly Leu Val Pro Met Leu Arg Val Tyr Asn Asn Thr Ala Arg Tyr
                 275                 280                 285

 Val Asp Gln Gly Gly Asn Lys Arg Pro Gly Ala Phe Ala Ile Tyr
                 290                 295                 300

 Leu Glu Pro Trp His Leu Asp Ile Phe Glu Phe Leu Asp Leu Lys
                 305                 310                 315

 Lys Asn Thr Gly Lys Glu Glu Gln Arg Ala Arg Asp Leu Phe Phe
                 320                 325                 330

 Ala Leu Trp Ile Pro Asp Leu Phe Met Lys Arg Val Glu Thr Asn
                 335                 340                 345

 Gln Asp Trp Ser Leu Met Cys Pro Asn Glu Cys Pro Gly Leu Asp
                 350                 355                 360

 Glu Val Trp Gly Glu Glu Phe Glu Lys Leu Tyr Ala Ser Tyr Glu
                 365                 370                 375

 Lys Gln Gly Arg Val Arg Lys Val Val Lys Ala Gln Gln Leu Trp
                 380                 385                 390

 Tyr Ala Ile Ile Glu Ser Gln Thr Glu Thr Gly Thr Pro Tyr Met
                 395                 400                 405

 Leu Tyr Lys Asp Ser Cys Asn Arg Lys Ser Asn Gln Gln Asn Leu
                 410                 415                 420

 Gly Thr Ile Lys Cys Ser Asn Leu Cys Thr Glu Ile Val Glu Tyr
                 425                 430                 435

 Thr Ser Lys Asp Glu Val Ala Val Cys Asn Leu Ala Ser Leu Ala
                 440                 445                 450

 Leu Asn Met Tyr Val Thr Ser Glu His Thr Tyr Asp Phe Lys Lys
                 455                 460                 465

 Leu Ala Glu Val Thr Lys Val Val Val Arg Asn Leu Asn Lys Ile
                 470                 475                 480

 Ile Asp Ile Asn Tyr Tyr Pro Val Pro Glu Ala Cys Leu Ser Asn
                 485                 490                 495

 Lys Arg His Arg Pro Ile Gly Ile Gly Val Gln Gly Leu Ala Asp
                 500                 505                 510

 Ala Phe Ile Leu Met Arg Tyr Pro Phe Glu Ser Ala Glu Ala Gln
                 515                 520                 525

 Leu Leu Asn Lys Gln Ile Phe Glu Thr Ile Tyr Tyr Gly Ala Leu
                 530                 535                 540

 Glu Ala Ser Cys Asp Leu Ala Lys Glu Gln Gly Pro Tyr Glu Thr
                 545                 550                 555

 Tyr Glu Gly Ser Pro Val Ser Lys Gly Ile Leu Gln Tyr Asp Met
                 560                 565                 570

 Trp Asn Val Thr Pro Thr Asp Leu Trp Asp Trp Lys Val Leu Lys
                 575                 580                 585

 Glu Lys Ile Ala Lys Tyr Gly Ile Arg Asn Ser Leu Leu Ile Ala
                 590                 595                 600

 Pro Met Pro Thr Ala Ser Thr Ala Gln Ile Leu Gly Asn Asn Glu
                 605                 610                 615

 Ser Ile Glu Pro Tyr Thr Ser Asn Ile Tyr Thr Arg Arg Val Leu
                 620                 625                 630

 Ser Gly Glu Phe Gln Ile Val Asn Pro His Leu Leu Lys Asp Leu
                 635                 640                 645

 Thr Glu Arg Gly Leu Trp His Glu Glu Met Lys Asn Gln Ile Ile
                 650                 655                 660

 Ala Cys Asn Gly Ser Ile Gln Ser Ile Pro Glu Ile Pro Asp Asp
                 665                 670                 675

 Leu Lys Gln Leu Tyr Lys Thr Val Trp Glu Ile Ser Gln Lys Thr
                 680                 685                 690

 Val Leu Lys Met Ala Ala Glu Arg Gly Ala Phe Ile Asp Gln Ser
                 695                 700                 705

 Gln Ser Leu Asn Ile His Ile Ala Glu Pro Asn Tyr Gly Lys Leu
                 710                 715                 720

 Thr Ser Met His Phe Tyr Gly Trp Lys Gln Gly Leu Lys Thr Gly
                 725                 730                 735

 Met Tyr Tyr Leu Arg Thr Arg Pro Ala Ala Asn Pro Ile Gln Phe
                 740                 745                 750

 Thr Leu Asn Lys Glu Lys Leu Lys Asp Lys Glu Lys Val Ser Lys
                 755                 760                 765

 Glu Glu Glu Glu Lys Glu Arg Asn Thr Ala Ala Met Val Cys Ser
                 770                 775                 780

 Leu Glu Asn Arg Asp Glu Cys Leu Met Cys Gly Ser
                 785                 790

<210> 345
<211> 2465
<212> DNA
<213> Homo sapien

<400> 345
 gagcagcgcg gcctgacggg accaaggcgg cgggagtctg cggtcgttcc 50

 ctcggctgtg gaccgggcgg cacgcacgcg gtgcagggta acatggcgga 100

 tgcggaagta attattttgc caaagaaaca taagaagaaa aaggagcgga 150

 agtcattgcc agaagaagat gtagccgaaa tacaacacgc tgaagaattt 200

 cttatcaaac ctgaatccaa agttgctaag ttggacacgt ctcagtggcc 250

 ccttttgcta aagaattttg ataagctgaa tgtaaggaca acacactata 300

 cacctcttgc atgtggttca aatcctctga agagagagat tggggactat 350

 atcaggacag gtttcattaa tcttgacaag ccctctaacc cctcttccca 400

 tgaggtggta gcctggattc gacggatact tcgggtggag aagacagggc 450

 acagtggtac tctggatccc aaggtgactg gttgtttaat cgtgtgcata 500

 gaacgagcca ctcgcttggt gaagtcacaa cagagtgcag gcaaagagta 550

 tgtggggatt gtccggctgc acaatgctat tgaagggggg acccagcttt 600

 ctagggccct agaaactctg acaggtgcct tattccagcg acccccactt 650

 attgctgcag taaagaggca gctccgagtg aggaccatct acgagagcaa 700

 aatgattgaa tacgatcctg aaagaagatt aggaatcttt tgggtgagtt 750

 gtgaggctgg cacctacatt cggacattat gtgtgcacct tggtttgtta 800

 ttgggagttg gtggtcagat gcaggagctt cggagggttc gttctggagt 850

 catgagtgaa aaggaccaca tggtgacaat gcatgatgtg cttgatgctc 900

 agtggctgta tgataaccac aaggatgaga gttacctgcg gcgagttgtt 950

 taccctttgg aaaagctgtt gacatctcat aaacggctgg ttatgaaaga 1000

 cagtgcagta aatgccatct gctatggggc caagattatg cttccaggtg 1050

 ttcttcgata tgaggacggc attgaggtca atcaggagat tgtggttatc 1100

 accaccaaag gagaagcaat ctgcatggct attgcattaa tgaccacagc 1150

 ggtcatctct acctgcgacc atggtatagt agccaagatc aagagagtga 1200

 tcatggagag agacacttac cctcggaagt ggggtttagg tccaaaggca 1250

 agtcagaaga agctgatgat caagcagggc cttctggaca agcatgggaa 1300

 gcccacagac agcacacctg ccacctggaa gcaggagtat gttgactaca 1350

 gtgagtctgc caaaaaagag gtggttgctg aagtggtaaa agccccgcag 1400

 gtagttgccg aagcagcaaa aactgcgaag cggaagcgag agagtgagag 1450

 tgaaagtgac gagactcctc cagcagctcc tcagttgatc aagaaggaaa 1500

 agaagaagag taagaaggac aagaaggcca aagctggtct ggagagcggg 1550

 gccgagcctg gagatgggga cagtgatacc accaagaaga agaagaagaa 1600

 gaagaaagca aaagaggtag aattggtttc tgagtagtga aggccacttg 1650

 aagctggagg agaaactaaa gccttattga gaaaacatgt tatagatcct 1700

 tttgttgctg agagagtgga acataggtcc tagacagggt gaagagttct 1750

 ggcacatttt agctgctact ttgagacctc ggtgatgtta cctggtgtgg 1800

 tcatcccatc ttgtcctgtt ttaaggatat gggtggtgaa agatgaaaga 1850

 ggcagagttt atcccaatga cttctctgtt tgagttggga agcctcacct 1900

 tcagacccag taactgtccg cagctgtctg ctagtggttg tcttaacatc 1950

 gtagtcctag tttgcatttt ttaaatcccc tctgtttaaa aggtttgtaa 2000

 aacaaaaaca aaaaactaag tctgctcagt gaaatgctgt agaaccctaa 2050

 ataagtggta gaagagtgtc actgaatttt gtctctgaat tcagtataac 2100

 tgagttttgt ccatgctggt gtctgggtta taggcctgat gggcctggta 2150

 gttttccatc ttgttctggc ctagaggtca gtcctttgca cttcctcaaa 2200

 gcttgtgtac agtgctcacc taaatccatc tgactacttg ttcctgtgcc 2250

 ctcttgtttt aggcctcgtt tacttttaaa aaatgaaatt gttcattgct 2300

 gggagaagaa tgttgtaatt tttacttatt aaagtcaact tgttaagttt 2350

 tttatgtatt cctgttgggt tttcttgttg atctcatgct agcagagcaa 2400

 aaattgtaaa atattttgat taaaaatcta gggaccttta tgtcctattt 2450

 ggaattcgat atcaa 2465

<210> 346
<211> 514
<212> PRT
<213> Homo sapien

<400> 346
 Met Ala Asp Ala Glu Val Ile Ile Leu Pro Lys Lys His Lys Lys
   1               5                  10                  15

 Lys Lys Glu Arg Lys Ser Leu Pro Glu Glu Asp Val Ala Glu Ile
                  20                  25                  30

 Gln His Ala Glu Glu Phe Leu Ile Lys Pro Glu Ser Lys Val Ala
                  35                  40                  45

 Lys Leu Asp Thr Ser Gln Trp Pro Leu Leu Leu Lys Asn Phe Asp
                  50                  55                  60

 Lys Leu Asn Val Arg Thr Thr His Tyr Thr Pro Leu Ala Cys Gly
                  65                  70                  75

 Ser Asn Pro Leu Lys Arg Glu Ile Gly Asp Tyr Ile Arg Thr Gly
                  80                  85                  90

 Phe Ile Asn Leu Asp Lys Pro Ser Asn Pro Ser Ser His Glu Val
                  95                 100                 105

 Val Ala Trp Ile Arg Arg Ile Leu Arg Val Glu Lys Thr Gly His
                 110                 115                 120

 Ser Gly Thr Leu Asp Pro Lys Val Thr Gly Cys Leu Ile Val Cys
                 125                 130                 135

 Ile Glu Arg Ala Thr Arg Leu Val Lys Ser Gln Gln Ser Ala Gly
                 140                 145                 150

 Lys Glu Tyr Val Gly Ile Val Arg Leu His Asn Ala Ile Glu Gly
                 155                 160                 165

 Gly Thr Gln Leu Ser Arg Ala Leu Glu Thr Leu Thr Gly Ala Leu
                 170                 175                 180

 Phe Gln Arg Pro Pro Leu Ile Ala Ala Val Lys Arg Gln Leu Arg
                 185                 190                 195

 Val Arg Thr Ile Tyr Glu Ser Lys Met Ile Glu Tyr Asp Pro Glu
                 200                 205                 210

 Arg Arg Leu Gly Ile Phe Trp Val Ser Cys Glu Ala Gly Thr Tyr
                 215                 220                 225

 Ile Arg Thr Leu Cys Val His Leu Gly Leu Leu Leu Gly Val Gly
                 230                 235                 240

 Gly Gln Met Gln Glu Leu Arg Arg Val Arg Ser Gly Val Met Ser
                 245                 250                 255

 Glu Lys Asp His Met Val Thr Met His Asp Val Leu Asp Ala Gln
                 260                 265                 270

 Trp Leu Tyr Asp Asn His Lys Asp Glu Ser Tyr Leu Arg Arg Val
                 275                 280                 285

 Val Tyr Pro Leu Glu Lys Leu Leu Thr Ser His Lys Arg Leu Val
                 290                 295                 300

 Met Lys Asp Ser Ala Val Asn Ala Ile Cys Tyr Gly Ala Lys Ile
                 305                 310                 315

 Met Leu Pro Gly Val Leu Arg Tyr Glu Asp Gly Ile Glu Val Asn
                 320                 325                 330

 Gln Glu Ile Val Val Ile Thr Thr Lys Gly Glu Ala Ile Cys Met
                 335                 340                 345

 Ala Ile Ala Leu Met Thr Thr Ala Val Ile Ser Thr Cys Asp His
                 350                 355                 360

 Gly Ile Val Ala Lys Ile Lys Arg Val Ile Met Glu Arg Asp Thr
                 365                 370                 375

 Tyr Pro Arg Lys Trp Gly Leu Gly Pro Lys Ala Ser Gln Lys Lys
                 380                 385                 390

 Leu Met Ile Lys Gln Gly Leu Leu Asp Lys His Gly Lys Pro Thr
                 395                 400                 405

 Asp Ser Thr Pro Ala Thr Trp Lys Gln Glu Tyr Val Asp Tyr Ser
                 410                 415                 420

 Glu Ser Ala Lys Lys Glu Val Val Ala Glu Val Val Lys Ala Pro
                 425                 430                 435

 Gln Val Val Ala Glu Ala Ala Lys Thr Ala Lys Arg Lys Arg Glu
                 440                 445                 450

 Ser Glu Ser Glu Ser Asp Glu Thr Pro Pro Ala Ala Pro Gln Leu
                 455                 460                 465

 Ile Lys Lys Glu Lys Lys Lys Ser Lys Lys Asp Lys Lys Ala Lys
                 470                 475                 480

 Ala Gly Leu Glu Ser Gly Ala Glu Pro Gly Asp Gly Asp Ser Asp
                 485                 490                 495

 Thr Thr Lys Lys Lys Lys Lys Lys Lys Lys Ala Lys Glu Val Glu
                 500                 505                 510

 Leu Val Ser Glu


<210> 347
<211> 2465
<212> DNA
<213> Homo sapien

<400> 347
 gagcagcgcg gcctgacggg accaaggcgg cgggagtctg cggtcgttcc 50

 ctcggctgtg gaccgggcgg cacgcacgcg gtgcagggta acatggcgga 100

 tgcggaagta attattttgc caaagaaaca taagaagaaa aaggagcgga 150

 agtcattgcc agaagaagat gtagccgaaa tacaacacgc tgaagaattt 200

 cttatcaaac ctgaatccaa agttgctaag ttggacacgt ctcagtggcc 250

 ccttttgcta aagaattttg ataagctgaa tgtaaggaca acacactata 300

 cacctcttgc atgtggttca aatcctctga agagagagat tggggactat 350

 atcaggacag gtttcattaa tcttgacaag ccctctaacc cctcttccca 400

 tgaggtggta gcctggattc gacggatact tcgggtggag aagacagggc 450

 acagtggtac tctggatccc aaggtgactg gttgtttaat cgtgtgcata 500

 gaacgagcca ctcgcttggt gaagtcacaa cagagtgcag gcaaagagta 550

 tgtggggatt gtccggctgc acaatgctat tgaagggggg acccagcttt 600

 ctagggccct agaaactctg acaggtgcct tattccagcg acccccactt 650

 attgctgcag taaagaggca gctccgagtg aggaccatct acgagagcaa 700

 aatgattgaa tacgatcctg aaagaagatt aggaatcttt tgggtgagtt 750

 gtgaggctgg cacctacatt cggacattat gtgtgcacct tggtttgtta 800

 ttgggagttg gtggtcagat gcaggagctt cggagggttc gttctggagt 850

 catgagtgaa aaggaccaca tggtgacaat gcatgatgtg cttgatgctc 900

 agtggctgta tgataaccac aaggatgaga gttacctgcg gcgagttgtt 950

 taccctttgg aaaagctgtt gacatctcat aaacggctgg ttatgaaaga 1000

 cagtgcagta aatgccatct gctatggggc caagattatg cttccaggtg 1050

 ttcttcgata tgaggacggc attgaggtca atcaggagat tgtggttatc 1100

 accaccaaag gagaagcaat ctgcatggct attgcattaa tgaccacagc 1150

 ggtcatctct acctgcgacc atggtatagt agccaagatc aagagagtga 1200

 tcatggagag agacacttac cctcggaagt ggggtttagg tccaaaggca 1250

 agtcagaaga agctgatgat caagcagggc cttctggaca agcatgggaa 1300

 gcccacagac agcacacctg ccacctggaa gcaggagtat gttgactaca 1350

 gtgagtctgc caaaaaagag gtggttgctg aagtggtaaa agccccgcag 1400

 gtagttgccg aagcagcaaa aactgcgaag cggaagcgag agagtgagag 1450

 tgaaagtgac gagactcctc cagcagctcc tcagttgatc aagaaggaaa 1500

 agaagaagag taagaaggac aagaaggcca aagctggtct ggagagcggg 1550

 gccgagcctg gagatgggga cagtgatacc accaagaaga agaagaagaa 1600

 gaagaaagca aaagaggtag aattggtttc tgagtagtga aggccacttg 1650

 aagctggagg agaaactaaa gccttattga gaaaacatgt tatagatcct 1700

 tttgttgctg agagagtgga acataggtcc tagacagggt gaagagttct 1750

 ggcacatttt agctgctact ttgagacctc ggtgatgtta cctggtgtgg 1800

 tcatcccatc ttgtcctgtt ttaaggatat gggtggtgaa agatgaaaga 1850

 ggcagagttt atcccaatga cttctctgtt tgagttggga agcctcacct 1900

 tcagacccag taactgtccg cagctgtctg ctagtggttg tcttaacatc 1950

 gtagtcctag tttgcatttt ttaaatcccc tctgtttaaa aggtttgtaa 2000

 aacaaaaaca aaaaactaag tctgctcagt gaaatgctgt agaaccctaa 2050

 ataagtggta gaagagtgtc actgaatttt gtctctgaat tcagtataac 2100

 tgagttttgt ccatgctggt gtctgggtta taggcctgat gggcctggta 2150

 gttttccatc ttgttctggc ctagaggtca gtcctttgca cttcctcaaa 2200

 gcttgtgtac agtgctcacc taaatccatc tgactacttg ttcctgtgcc 2250

 ctcttgtttt aggcctcgtt tacttttaaa aaatgaaatt gttcattgct 2300

 gggagaagaa tgttgtaatt tttacttatt aaagtcaact tgttaagttt 2350

 tttatgtatt cctgttgggt tttcttgttg atctcatgct agcagagcaa 2400

 aaattgtaaa atattttgat taaaaatcta gggaccttta tgtcctattt 2450

 ggaattcgat atcaa 2465

<210> 348
<211> 514
<212> PRT
<213> Homo sapien

<400> 348
 Met Ala Asp Ala Glu Val Ile Ile Leu Pro Lys Lys His Lys Lys
   1               5                  10                  15

 Lys Lys Glu Arg Lys Ser Leu Pro Glu Glu Asp Val Ala Glu Ile
                  20                  25                  30

 Gln His Ala Glu Glu Phe Leu Ile Lys Pro Glu Ser Lys Val Ala
                  35                  40                  45

 Lys Leu Asp Thr Ser Gln Trp Pro Leu Leu Leu Lys Asn Phe Asp
                  50                  55                  60

 Lys Leu Asn Val Arg Thr Thr His Tyr Thr Pro Leu Ala Cys Gly
                  65                  70                  75

 Ser Asn Pro Leu Lys Arg Glu Ile Gly Asp Tyr Ile Arg Thr Gly
                  80                  85                  90

 Phe Ile Asn Leu Asp Lys Pro Ser Asn Pro Ser Ser His Glu Val
                  95                 100                 105

 Val Ala Trp Ile Arg Arg Ile Leu Arg Val Glu Lys Thr Gly His
                 110                 115                 120

 Ser Gly Thr Leu Asp Pro Lys Val Thr Gly Cys Leu Ile Val Cys
                 125                 130                 135

 Ile Glu Arg Ala Thr Arg Leu Val Lys Ser Gln Gln Ser Ala Gly
                 140                 145                 150

 Lys Glu Tyr Val Gly Ile Val Arg Leu His Asn Ala Ile Glu Gly
                 155                 160                 165

 Gly Thr Gln Leu Ser Arg Ala Leu Glu Thr Leu Thr Gly Ala Leu
                 170                 175                 180

 Phe Gln Arg Pro Pro Leu Ile Ala Ala Val Lys Arg Gln Leu Arg
                 185                 190                 195

 Val Arg Thr Ile Tyr Glu Ser Lys Met Ile Glu Tyr Asp Pro Glu
                 200                 205                 210

 Arg Arg Leu Gly Ile Phe Trp Val Ser Cys Glu Ala Gly Thr Tyr
                 215                 220                 225

 Ile Arg Thr Leu Cys Val His Leu Gly Leu Leu Leu Gly Val Gly
                 230                 235                 240

 Gly Gln Met Gln Glu Leu Arg Arg Val Arg Ser Gly Val Met Ser
                 245                 250                 255

 Glu Lys Asp His Met Val Thr Met His Asp Val Leu Asp Ala Gln
                 260                 265                 270

 Trp Leu Tyr Asp Asn His Lys Asp Glu Ser Tyr Leu Arg Arg Val
                 275                 280                 285

 Val Tyr Pro Leu Glu Lys Leu Leu Thr Ser His Lys Arg Leu Val
                 290                 295                 300

 Met Lys Asp Ser Ala Val Asn Ala Ile Cys Tyr Gly Ala Lys Ile
                 305                 310                 315

 Met Leu Pro Gly Val Leu Arg Tyr Glu Asp Gly Ile Glu Val Asn
                 320                 325                 330

 Gln Glu Ile Val Val Ile Thr Thr Lys Gly Glu Ala Ile Cys Met
                 335                 340                 345

 Ala Ile Ala Leu Met Thr Thr Ala Val Ile Ser Thr Cys Asp His
                 350                 355                 360

 Gly Ile Val Ala Lys Ile Lys Arg Val Ile Met Glu Arg Asp Thr
                 365                 370                 375

 Tyr Pro Arg Lys Trp Gly Leu Gly Pro Lys Ala Ser Gln Lys Lys
                 380                 385                 390

 Leu Met Ile Lys Gln Gly Leu Leu Asp Lys His Gly Lys Pro Thr
                 395                 400                 405

 Asp Ser Thr Pro Ala Thr Trp Lys Gln Glu Tyr Val Asp Tyr Ser
                 410                 415                 420

 Glu Ser Ala Lys Lys Glu Val Val Ala Glu Val Val Lys Ala Pro
                 425                 430                 435

 Gln Val Val Ala Glu Ala Ala Lys Thr Ala Lys Arg Lys Arg Glu
                 440                 445                 450

 Ser Glu Ser Glu Ser Asp Glu Thr Pro Pro Ala Ala Pro Gln Leu
                 455                 460                 465

 Ile Lys Lys Glu Lys Lys Lys Ser Lys Lys Asp Lys Lys Ala Lys
                 470                 475                 480

 Ala Gly Leu Glu Ser Gly Ala Glu Pro Gly Asp Gly Asp Ser Asp
                 485                 490                 495

 Thr Thr Lys Lys Lys Lys Lys Lys Lys Lys Ala Lys Glu Val Glu
                 500                 505                 510

 Leu Val Ser Glu


<210> 349
<211> 1904
<212> DNA
<213> Homo sapien

<400> 349
 agctatttca aggcgcgcgc ctcgtggtgg actcaccgct agcccgcagc 50

 gctcggcttc ctggtaattc ttcacctctt ttctcagctc cctgcagcat 100

 gggtgctggg ccctccttgc tgctcgccgc cctcctgctg cttctctccg 150

 gcgacggcgc cgtgcgctgc gacacacctg ccaactgcac ctatcttgac 200

 ctgctgggca cctgggtctt ccaggtgggc tccagcggtt cccagcgcga 250

 tgtcaactgc tcggttatgg gaccacaaga aaaaaaagta gtggtgtacc 300

 ttcagaagct ggatacagca tatgatgacc ttggcaattc tggccatttc 350

 accatcattt acaaccaagg ctttgagatt gtgttgaatg actacaagtg 400

 gtttgccttt tttaagtata aagaagaggg cagcaaggtg accacttact 450

 gcaacgagac aatgactggg tgggtgcatg atgtgttggg ccggaactgg 500

 gcttgtttca ccggaaagaa ggtgggaact gcctctgaga atgtgtatgt 550

 caacacagca caccttaaga attctcagga aaagtattct aataggctct 600

 acaagtatga tcacaacttt gtgaaagcta tcaatgccat tcagaagtct 650

 tggactgcaa ctacatacat ggaatatgag actcttaccc tgggagatat 700

 gattaggaga agtggtggcc acagtcgaaa aatcccaagg cccaaacctg 750

 caccactgac tgctgaaata cagcaaaaga ttttgcattt gccaacatct 800

 tgggactgga gaaatgttca tggtatcaat tttgtcagtc ctgttcgaaa 850

 ccaagcatcc tgtggcagct gctactcatt tgcttctatg ggtatgctag 900

 aagcgagaat ccgtatacta accaacaatt ctcagacccc aatcctaagc 950

 cctcaggagg ttgtgtcttg tagccagtat gctcaaggct gtgaaggcgg 1000

 cttcccatac cttattgcag gaaagtacgc ccaagatttt gggctggtgg 1050

 aagaagcttg cttcccctac acaggcactg attctccatg caaaatgaag 1100

 gaagactgct ttcgttatta ctcctctgag taccactatg taggaggttt 1150

 ctatggaggc tgcaatgaag ccctgatgaa gcttgagttg gtccatcatg 1200

 ggcccatggc agttgctttt gaagtatatg atgacttcct ccactacaaa 1250

 aaggggatct accaccacac tggtctaaga gaccctttca acccctttga 1300

 gctgactaat catgctgttc tgcttgtggg ctatggcact gactcagcct 1350

 ctgggatgga ttactggatt gttaaaaaca gctggggcac cggctggggt 1400

 gagaatggct acttccggat ccgcagagga actgatgagt gtgcaattga 1450

 gagcatagca gtggcagcca caccaattcc taaattgtag ggtatgcctt 1500

 ccagtatttc ataatgatct gcatcagttg taaaggggaa ttggtatatt 1550

 cacagactgt agactttcag cagcaatctc agaagcttac aaatagattt 1600

 ccatgaagat atttgtcttc agaattaaaa ctgcccttaa ttttaatata 1650

 cctttcaatc ggccactggc catttttttc taagtattca attaagtggg 1700

 aattttctgg aagatggtca gctatgaagt aatagagttt gcttaatcat 1750

 ttgtaattca aacatgctat attttttaaa atcaatgtga aaacatagac 1800

 ttatttttaa attgtaccaa tcacaagaaa ataatggcaa taattatcaa 1850

 aacttttaaa atagatgctc atatttttaa aataaagttt taaaaataac 1900

 tgca 1904

<210> 350
<211> 463
<212> PRT
<213> Homo sapien

<400> 350
 Met Gly Ala Gly Pro Ser Leu Leu Leu Ala Ala Leu Leu Leu Leu
   1               5                  10                  15

 Leu Ser Gly Asp Gly Ala Val Arg Cys Asp Thr Pro Ala Asn Cys
                  20                  25                  30

 Thr Tyr Leu Asp Leu Leu Gly Thr Trp Val Phe Gln Val Gly Ser
                  35                  40                  45

 Ser Gly Ser Gln Arg Asp Val Asn Cys Ser Val Met Gly Pro Gln
                  50                  55                  60

 Glu Lys Lys Val Val Val Tyr Leu Gln Lys Leu Asp Thr Ala Tyr
                  65                  70                  75

 Asp Asp Leu Gly Asn Ser Gly His Phe Thr Ile Ile Tyr Asn Gln
                  80                  85                  90

 Gly Phe Glu Ile Val Leu Asn Asp Tyr Lys Trp Phe Ala Phe Phe
                  95                 100                 105

 Lys Tyr Lys Glu Glu Gly Ser Lys Val Thr Thr Tyr Cys Asn Glu
                 110                 115                 120

 Thr Met Thr Gly Trp Val His Asp Val Leu Gly Arg Asn Trp Ala
                 125                 130                 135

 Cys Phe Thr Gly Lys Lys Val Gly Thr Ala Ser Glu Asn Val Tyr
                 140                 145                 150

 Val Asn Thr Ala His Leu Lys Asn Ser Gln Glu Lys Tyr Ser Asn
                 155                 160                 165

 Arg Leu Tyr Lys Tyr Asp His Asn Phe Val Lys Ala Ile Asn Ala
                 170                 175                 180

 Ile Gln Lys Ser Trp Thr Ala Thr Thr Tyr Met Glu Tyr Glu Thr
                 185                 190                 195

 Leu Thr Leu Gly Asp Met Ile Arg Arg Ser Gly Gly His Ser Arg
                 200                 205                 210

 Lys Ile Pro Arg Pro Lys Pro Ala Pro Leu Thr Ala Glu Ile Gln
                 215                 220                 225

 Gln Lys Ile Leu His Leu Pro Thr Ser Trp Asp Trp Arg Asn Val
                 230                 235                 240

 His Gly Ile Asn Phe Val Ser Pro Val Arg Asn Gln Ala Ser Cys
                 245                 250                 255

 Gly Ser Cys Tyr Ser Phe Ala Ser Met Gly Met Leu Glu Ala Arg
                 260                 265                 270

 Ile Arg Ile Leu Thr Asn Asn Ser Gln Thr Pro Ile Leu Ser Pro
                 275                 280                 285

 Gln Glu Val Val Ser Cys Ser Gln Tyr Ala Gln Gly Cys Glu Gly
                 290                 295                 300

 Gly Phe Pro Tyr Leu Ile Ala Gly Lys Tyr Ala Gln Asp Phe Gly
                 305                 310                 315

 Leu Val Glu Glu Ala Cys Phe Pro Tyr Thr Gly Thr Asp Ser Pro
                 320                 325                 330

 Cys Lys Met Lys Glu Asp Cys Phe Arg Tyr Tyr Ser Ser Glu Tyr
                 335                 340                 345

 His Tyr Val Gly Gly Phe Tyr Gly Gly Cys Asn Glu Ala Leu Met
                 350                 355                 360

 Lys Leu Glu Leu Val His His Gly Pro Met Ala Val Ala Phe Glu
                 365                 370                 375

 Val Tyr Asp Asp Phe Leu His Tyr Lys Lys Gly Ile Tyr His His
                 380                 385                 390

 Thr Gly Leu Arg Asp Pro Phe Asn Pro Phe Glu Leu Thr Asn His
                 395                 400                 405

 Ala Val Leu Leu Val Gly Tyr Gly Thr Asp Ser Ala Ser Gly Met
                 410                 415                 420

 Asp Tyr Trp Ile Val Lys Asn Ser Trp Gly Thr Gly Trp Gly Glu
                 425                 430                 435

 Asn Gly Tyr Phe Arg Ile Arg Arg Gly Thr Asp Glu Cys Ala Ile
                 440                 445                 450

 Glu Ser Ile Ala Val Ala Ala Thr Pro Ile Pro Lys Leu
                 455                 460

<210> 351
<211> 1591
<212> DNA
<213> Homo sapien

<400> 351
 tctgggcgcg cgcgacgtca gtttgagttc tgtgttctcc ccgcccgtgt 50

 cccgcccgac ccgcgcccgc gatgctggcg ctgcgctgcg gctcccgctg 100

 gctcggcctg ctctccgtcc cgcgctccgt gccgctgcgc ctccccgcgg 150

 cccgcgcctg cagcaagggc tccggcgacc cgtcctcttc ctcctcctcc 200

 gggaacccgc tcgtgtacct ggacgtggac gccaacggga agccgctcgg 250

 ccgcgtggtg ctggagctga aggcagatgt cgtcccaaag acagctgaga 300

 acttcagagc cctgtgcact ggtgagaagg gcttcggcta caaaggctcc 350

 accttccaca gggtgatccc ttccttcatg tgccaggcgg gcgacttcac 400

 caaccacaat ggcacaggcg ggaagtccat ctacggaagc cgctttcctg 450

 acgagaactt tacactgaag cacgtggggc caggtgtcct gtccatggct 500

 aatgctggtc ctaacaccaa cggctcccag ttcttcatct gcaccataaa 550

 gacagactgg ttggatggca agcatgttgt gttcggtcac gtcaaagagg 600

 gcatggacgt cgtgaagaaa atagaatctt tcggctctaa gagtgggagg 650

 acatccaaga agattgtcat cacagactgt ggccagttga gctaatctgt 700

 ggccagggtg ctggcatggt ggcagctgca aatgtccatg cacccaggtg 750

 gccgcgttgg gctgtcagcc aaggtgcctg aaacgatacg tgtgcccact 800

 ccactgtcac agtgtgcctg aggaaggctg ctagggatgt tagacctcgg 850

 ccaggaccca ccacattgct tcctaatacc cacccttcct cacgacctca 900

 tttctgggca tctttgtgga catgatgtca cccacccctt gtcaagcatt 950

 gcctgtgatt gcccagccca gattcatctg tgccttggac atggtgatgg 1000

 tgatgggttg ccatccaagt gaaagtcttt tccttgacca agggggacag 1050

 tcagttttgc aaaaggactc taatacctgt ttaatattgt cttcctaatt 1100

 gggataattt aattaacaag attgactaga agtgaaactg caacactaac 1150

 ttccccgtgc tgtggtgtga cctgagttgg tgacacaggc cacagacccc 1200

 agagcttggc ttttgaaaca caactcaggg cttttgtgaa ggttcccccg 1250

 ctgagatctt tcctcctggt tactgtgaag cctgttggtt tgctgctgtc 1300

 gtttttgagg agggcccatg ggggtaggag cagttgaacc tgggaacaaa 1350

 cctcacttga gctgtgccta gacaatgtga attcctgtgt tgctaacaga 1400

 agtggcctgt aagctcctgt gctccggagg gaagcatttc ctggtaggct 1450

 ttgatttttc tgtgtgttaa agaaattcaa tctactcatg atgtgttatg 1500

 cataaaacat ttctggaaca tggatttgtg ttcaccttaa atgtgaaaat 1550

 aaatcctatt ttctatggaa aaaaaaaaaa aaaaaaaaaa a 1591

<210> 352
<211> 207
<212> PRT
<213> Homo sapien

<400> 352
 Met Leu Ala Leu Arg Cys Gly Ser Arg Trp Leu Gly Leu Leu Ser
   1               5                  10                  15

 Val Pro Arg Ser Val Pro Leu Arg Leu Pro Ala Ala Arg Ala Cys
                  20                  25                  30

 Ser Lys Gly Ser Gly Asp Pro Ser Ser Ser Ser Ser Ser Gly Asn
                  35                  40                  45

 Pro Leu Val Tyr Leu Asp Val Asp Ala Asn Gly Lys Pro Leu Gly
                  50                  55                  60

 Arg Val Val Leu Glu Leu Lys Ala Asp Val Val Pro Lys Thr Ala
                  65                  70                  75

 Glu Asn Phe Arg Ala Leu Cys Thr Gly Glu Lys Gly Phe Gly Tyr
                  80                  85                  90

 Lys Gly Ser Thr Phe His Arg Val Ile Pro Ser Phe Met Cys Gln
                  95                 100                 105

 Ala Gly Asp Phe Thr Asn His Asn Gly Thr Gly Gly Lys Ser Ile
                 110                 115                 120

 Tyr Gly Ser Arg Phe Pro Asp Glu Asn Phe Thr Leu Lys His Val
                 125                 130                 135

 Gly Pro Gly Val Leu Ser Met Ala Asn Ala Gly Pro Asn Thr Asn
                 140                 145                 150

 Gly Ser Gln Phe Phe Ile Cys Thr Ile Lys Thr Asp Trp Leu Asp
                 155                 160                 165

 Gly Lys His Val Val Phe Gly His Val Lys Glu Gly Met Asp Val
                 170                 175                 180

 Val Lys Lys Ile Glu Ser Phe Gly Ser Lys Ser Gly Arg Thr Ser
                 185                 190                 195

 Lys Lys Ile Val Ile Thr Asp Cys Gly Gln Leu Ser
                 200                 205

<210> 353
<211> 1591
<212> DNA
<213> Homo sapien

<400> 353
 tctgggcgcg cgcgacgtca gtttgagttc tgtgttctcc ccgcccgtgt 50

 cccgcccgac ccgcgcccgc gatgctggcg ctgcgctgcg gctcccgctg 100

 gctcggcctg ctctccgtcc cgcgctccgt gccgctgcgc ctccccgcgg 150

 cccgcgcctg cagcaagggc tccggcgacc cgtcctcttc ctcctcctcc 200

 gggaacccgc tcgtgtacct ggacgtggac gccaacggga agccgctcgg 250

 ccgcgtggtg ctggagctga aggcagatgt cgtcccaaag acagctgaga 300

 acttcagagc cctgtgcact ggtgagaagg gcttcggcta caaaggctcc 350

 accttccaca gggtgatccc ttccttcatg tgccaggcgg gcgacttcac 400

 caaccacaat ggcacaggcg ggaagtccat ctacggaagc cgctttcctg 450

 acgagaactt tacactgaag cacgtggggc caggtgtcct gtccatggct 500

 aatgctggtc ctaacaccaa cggctcccag ttcttcatct gcaccataaa 550

 gacagactgg ttggatggca agcatgttgt gttcggtcac gtcaaagagg 600

 gcatggacgt cgtgaagaaa atagaatctt tcggctctaa gagtgggagg 650

 acatccaaga agattgtcat cacagactgt ggccagttga gctaatctgt 700

 ggccagggtg ctggcatggt ggcagctgca aatgtccatg cacccaggtg 750

 gccgcgttgg gctgtcagcc aaggtgcctg aaacgatacg tgtgcccact 800

 ccactgtcac agtgtgcctg aggaaggctg ctagggatgt tagacctcgg 850

 ccaggaccca ccacattgct tcctaatacc cacccttcct cacgacctca 900

 tttctgggca tctttgtgga catgatgtca cccacccctt gtcaagcatt 950

 gcctgtgatt gcccagccca gattcatctg tgccttggac atggtgatgg 1000

 tgatgggttg ccatccaagt gaaagtcttt tccttgacca agggggacag 1050

 tcagttttgc aaaaggactc taatacctgt ttaatattgt cttcctaatt 1100

 gggataattt aattaacaag attgactaga agtgaaactg caacactaac 1150

 ttccccgtgc tgtggtgtga cctgagttgg tgacacaggc cacagacccc 1200

 agagcttggc ttttgaaaca caactcaggg cttttgtgaa ggttcccccg 1250

 ctgagatctt tcctcctggt tactgtgaag cctgttggtt tgctgctgtc 1300

 gtttttgagg agggcccatg ggggtaggag cagttgaacc tgggaacaaa 1350

 cctcacttga gctgtgccta gacaatgtga attcctgtgt tgctaacaga 1400

 agtggcctgt aagctcctgt gctccggagg gaagcatttc ctggtaggct 1450

 ttgatttttc tgtgtgttaa agaaattcaa tctactcatg atgtgttatg 1500

 cataaaacat ttctggaaca tggatttgtg ttcaccttaa atgtgaaaat 1550

 aaatcctatt ttctatggaa aaaaaaaaaa aaaaaaaaaa a 1591

<210> 354
<211> 207
<212> PRT
<213> Homo sapien

<400> 354
 Met Leu Ala Leu Arg Cys Gly Ser Arg Trp Leu Gly Leu Leu Ser
   1               5                  10                  15

 Val Pro Arg Ser Val Pro Leu Arg Leu Pro Ala Ala Arg Ala Cys
                  20                  25                  30

 Ser Lys Gly Ser Gly Asp Pro Ser Ser Ser Ser Ser Ser Gly Asn
                  35                  40                  45

 Pro Leu Val Tyr Leu Asp Val Asp Ala Asn Gly Lys Pro Leu Gly
                  50                  55                  60

 Arg Val Val Leu Glu Leu Lys Ala Asp Val Val Pro Lys Thr Ala
                  65                  70                  75

 Glu Asn Phe Arg Ala Leu Cys Thr Gly Glu Lys Gly Phe Gly Tyr
                  80                  85                  90

 Lys Gly Ser Thr Phe His Arg Val Ile Pro Ser Phe Met Cys Gln
                  95                 100                 105

 Ala Gly Asp Phe Thr Asn His Asn Gly Thr Gly Gly Lys Ser Ile
                 110                 115                 120

 Tyr Gly Ser Arg Phe Pro Asp Glu Asn Phe Thr Leu Lys His Val
                 125                 130                 135

 Gly Pro Gly Val Leu Ser Met Ala Asn Ala Gly Pro Asn Thr Asn
                 140                 145                 150

 Gly Ser Gln Phe Phe Ile Cys Thr Ile Lys Thr Asp Trp Leu Asp
                 155                 160                 165

 Gly Lys His Val Val Phe Gly His Val Lys Glu Gly Met Asp Val
                 170                 175                 180

 Val Lys Lys Ile Glu Ser Phe Gly Ser Lys Ser Gly Arg Thr Ser
                 185                 190                 195

 Lys Lys Ile Val Ile Thr Asp Cys Gly Gln Leu Ser
                 200                 205

<210> 355
<211> 1375
<212> DNA
<213> Homo sapien

<400> 355
 aaaagcaagc caggaggtgc ttgcggccgc ttctagtagt ttccaggcgc 50

 tgccgggcgg ctggcactaa gcggtcctga ggctgtggct acggctgctc 100

 cggagctggt ggcgccgcga taggagagcc gatggccaag tggggtgagg 150

 gagacccacg ctggatcgtg gaggagcggg cggacgccac caacgtcaac 200

 aactggcact ggacggagag agatgcttca aattggtcca cggataagct 250

 gaaaacactg ttcttggcag tgcaggttca aaatgaagaa ggcaagtgtg 300

 aggtgacgga agtgagtaag cttgatggag aggcatccat taacaatcgc 350

 aaagggaaac ttatcttctt ttatgaatgg agcgtcaaac taaactggac 400

 aggtacttct aagtcaggag tacagtacaa aggacatgtg gagatcccca 450

 atttgtctga tgaaaacagc gtggatgaag tggagattag tgtgagcctt 500

 gccaaagatg agcctgacac aaatctcgtg gccttaatga aggaagaagg 550

 ggtgaaactt ctaagagaag caatgggaat ttacatcagc accctcaaaa 600

 cagagttcac ccagggcatg atcttaccta caatgaatgg agagtcagta 650

 gacccagtgg ggcagccagc actgaaaact gaggagcgca aggctaagcc 700

 tgctccttca aaaacccagg ccagacctgt tggagtcaaa atccccactt 750

 gtaagatcac tcttaaggaa accttcctga cgtcaccaga ggagctctat 800

 agagtgttta ccacccaaga gctggtgcag gcctttaccc atgctcctgc 850

 aacattagaa gcagacagag gtggaaagtt ccacatggta gatggcaacg 900

 tctctgggga atttactgat ctggtccctg agaaacatat tgtgatgaag 950

 tggaggttta aatcttggcc agagggacac tttgccacca tcaccttgac 1000

 cttcatcgac aagaacggag agactgagct gtgcatggaa ggtcgaggca 1050

 tccctgctcc tgaggaagag cggacacgac agggctggca gcggtactac 1100

 tttgagggca ttaaacagac ctttggctat ggcgcacgct tattttaggg 1150

 ccagcggcag gggactccag cctgctggac acttcagtcc agctctctcc 1200

 tgactggggc ttgcgactca caggattgca tcgtcccagc tgctaacttg 1250

 gggccggggc ccctcccttc cacatatacc ttgggtttgt gcatgttttc 1300

 tgctgggtgg gttcagaggg caatttctct tttatgtgta catatgctaa 1350

 ataaacataa tttaaaaaac aaaaa 1375

<210> 356
<211> 338
<212> PRT
<213> Homo sapien

<400> 356
 Met Ala Lys Trp Gly Glu Gly Asp Pro Arg Trp Ile Val Glu Glu
   1               5                  10                  15

 Arg Ala Asp Ala Thr Asn Val Asn Asn Trp His Trp Thr Glu Arg
                  20                  25                  30

 Asp Ala Ser Asn Trp Ser Thr Asp Lys Leu Lys Thr Leu Phe Leu
                  35                  40                  45

 Ala Val Gln Val Gln Asn Glu Glu Gly Lys Cys Glu Val Thr Glu
                  50                  55                  60

 Val Ser Lys Leu Asp Gly Glu Ala Ser Ile Asn Asn Arg Lys Gly
                  65                  70                  75

 Lys Leu Ile Phe Phe Tyr Glu Trp Ser Val Lys Leu Asn Trp Thr
                  80                  85                  90

 Gly Thr Ser Lys Ser Gly Val Gln Tyr Lys Gly His Val Glu Ile
                  95                 100                 105

 Pro Asn Leu Ser Asp Glu Asn Ser Val Asp Glu Val Glu Ile Ser
                 110                 115                 120

 Val Ser Leu Ala Lys Asp Glu Pro Asp Thr Asn Leu Val Ala Leu
                 125                 130                 135

 Met Lys Glu Glu Gly Val Lys Leu Leu Arg Glu Ala Met Gly Ile
                 140                 145                 150

 Tyr Ile Ser Thr Leu Lys Thr Glu Phe Thr Gln Gly Met Ile Leu
                 155                 160                 165

 Pro Thr Met Asn Gly Glu Ser Val Asp Pro Val Gly Gln Pro Ala
                 170                 175                 180

 Leu Lys Thr Glu Glu Arg Lys Ala Lys Pro Ala Pro Ser Lys Thr
                 185                 190                 195

 Gln Ala Arg Pro Val Gly Val Lys Ile Pro Thr Cys Lys Ile Thr
                 200                 205                 210

 Leu Lys Glu Thr Phe Leu Thr Ser Pro Glu Glu Leu Tyr Arg Val
                 215                 220                 225

 Phe Thr Thr Gln Glu Leu Val Gln Ala Phe Thr His Ala Pro Ala
                 230                 235                 240

 Thr Leu Glu Ala Asp Arg Gly Gly Lys Phe His Met Val Asp Gly
                 245                 250                 255

 Asn Val Ser Gly Glu Phe Thr Asp Leu Val Pro Glu Lys His Ile
                 260                 265                 270

 Val Met Lys Trp Arg Phe Lys Ser Trp Pro Glu Gly His Phe Ala
                 275                 280                 285

 Thr Ile Thr Leu Thr Phe Ile Asp Lys Asn Gly Glu Thr Glu Leu
                 290                 295                 300

 Cys Met Glu Gly Arg Gly Ile Pro Ala Pro Glu Glu Glu Arg Thr
                 305                 310                 315

 Arg Gln Gly Trp Gln Arg Tyr Tyr Phe Glu Gly Ile Lys Gln Thr
                 320                 325                 330

 Phe Gly Tyr Gly Ala Arg Leu Phe
                 335

<210> 357
<211> 1550
<212> DNA
<213> Homo sapien

<400> 357
 tgccgccgtc ccgcccgcca gcgccccagc gaggaagcag cgcgcagccc 50

 gcggcccagc gcacccgcag cagcgcccgc agctcgtccg cgccatgttc 100

 caggcggccg agcgccccca ggagtgggcc atggagggcc cccgcgacgg 150

 gctgaagaag gagcggctac tggacgaccg ccacgacagc ggcctggact 200

 ccatgaaaga cgaggagtac gagcagatgg tcaaggagct gcaggagatc 250

 cgcctcgagc cgcaggaggt gccgcgcggc tcggagccct ggaagcagca 300

 gctcaccgag gacggggact cgttcctgca cttggccatc atccatgaag 350

 aaaaggcact gaccatggaa gtgatccgcc aggtgaaggg agacctggct 400

 ttcctcaact tccagaacaa cctgcagcag actccactcc acttggctgt 450

 gatcaccaac cagccagaaa ttgctgaggc acttctggga gctggctgtg 500

 atcctgagct ccgagacttt cgaggaaata cccccctaca ccttgcctgt 550

 gagcagggct gcctggccag cgtgggagtc ctgactcagt cctgcaccac 600

 cccgcacctc cactccatcc tgaaggctac caactacaat ggccacacgt 650

 gtctacactt agcctctatc catggctacc tgggcatcgt ggagcttttg 700

 gtgtccttgg gtgctgatgt caatgctcag gagccctgta atggccggac 750

 tgcccttcac ctcgcagtgg acctgcaaaa tcctgacctg gtgtcactcc 800

 tgttgaagtg tggggctgat gtcaacagag ttacctacca gggctattct 850

 ccctaccagc tcacctgggg ccgcccaagc acccggatac agcagcagct 900

 gggccagctg acactagaaa accttcagat gctgccagag agtgaggatg 950

 aggagagcta tgacacagag tcagagttca cggagttcac agaggacgag 1000

 ctgccctatg atgactgtgt gtttggaggc cagcgtctga cgttatgagt 1050

 gcaaaggggc tgaaagaaca tggacttgta tatttgtaca aaaaaaaagt 1100

 tttatttttc taaaaaaaga aaaaagaaga aaaaatttaa agggtgtact 1150

 tatatccaca ctgcacactg cctagcccaa aacgtcttat tgtggtagga 1200

 tcagccctca ttttgttgct tttgtgaact ttttgtaggg gacgagaaag 1250

 atcattgaaa ttctgagaaa acttctttta aacctcacct ttgtggggtt 1300

 tttggagaag gttatcaaaa atttcatgga aggaccacat tttatattta 1350

 ttgtgcttcg agtgactgac cccagtggta tcctgtgaca tgtaacagcc 1400

 aggagtgtta agcgttcagt gatgtggggt gaaaagttac tacctgtcaa 1450

 ggtttgtgtt accctcctgt aaatggtgta cataatgtat tgttggtaat 1500

 tattttggta cttttatgat gtatatttat taaagagatt tttacaaatg 1550

<210> 358
<211> 317
<212> PRT
<213> Homo sapien

<400> 358
 Met Phe Gln Ala Ala Glu Arg Pro Gln Glu Trp Ala Met Glu Gly
   1               5                  10                  15

 Pro Arg Asp Gly Leu Lys Lys Glu Arg Leu Leu Asp Asp Arg His
                  20                  25                  30

 Asp Ser Gly Leu Asp Ser Met Lys Asp Glu Glu Tyr Glu Gln Met
                  35                  40                  45

 Val Lys Glu Leu Gln Glu Ile Arg Leu Glu Pro Gln Glu Val Pro
                  50                  55                  60

 Arg Gly Ser Glu Pro Trp Lys Gln Gln Leu Thr Glu Asp Gly Asp
                  65                  70                  75

 Ser Phe Leu His Leu Ala Ile Ile His Glu Glu Lys Ala Leu Thr
                  80                  85                  90

 Met Glu Val Ile Arg Gln Val Lys Gly Asp Leu Ala Phe Leu Asn
                  95                 100                 105

 Phe Gln Asn Asn Leu Gln Gln Thr Pro Leu His Leu Ala Val Ile
                 110                 115                 120

 Thr Asn Gln Pro Glu Ile Ala Glu Ala Leu Leu Gly Ala Gly Cys
                 125                 130                 135

 Asp Pro Glu Leu Arg Asp Phe Arg Gly Asn Thr Pro Leu His Leu
                 140                 145                 150

 Ala Cys Glu Gln Gly Cys Leu Ala Ser Val Gly Val Leu Thr Gln
                 155                 160                 165

 Ser Cys Thr Thr Pro His Leu His Ser Ile Leu Lys Ala Thr Asn
                 170                 175                 180

 Tyr Asn Gly His Thr Cys Leu His Leu Ala Ser Ile His Gly Tyr
                 185                 190                 195

 Leu Gly Ile Val Glu Leu Leu Val Ser Leu Gly Ala Asp Val Asn
                 200                 205                 210

 Ala Gln Glu Pro Cys Asn Gly Arg Thr Ala Leu His Leu Ala Val
                 215                 220                 225

 Asp Leu Gln Asn Pro Asp Leu Val Ser Leu Leu Leu Lys Cys Gly
                 230                 235                 240

 Ala Asp Val Asn Arg Val Thr Tyr Gln Gly Tyr Ser Pro Tyr Gln
                 245                 250                 255

 Leu Thr Trp Gly Arg Pro Ser Thr Arg Ile Gln Gln Gln Leu Gly
                 260                 265                 270

 Gln Leu Thr Leu Glu Asn Leu Gln Met Leu Pro Glu Ser Glu Asp
                 275                 280                 285

 Glu Glu Ser Tyr Asp Thr Glu Ser Glu Phe Thr Glu Phe Thr Glu
                 290                 295                 300

 Asp Glu Leu Pro Tyr Asp Asp Cys Val Phe Gly Gly Gln Arg Leu
                 305                 310                 315

 Thr Leu


<210> 359
<211> 2160
<212> DNA
<213> Homo sapien

<400> 359
 agccccctgc ccctcgccgc cccccgccgc ctgcctgggc cgggccgagg 50

 atgcggcgca gcgcctcggc ggccaggctt gctcccctcc ggcacgcctg 100

 ctaacttccc ccgctacgtc cccgttcgcc cgccgggccg ccccgtctcc 150

 ccgcggcctc cgggtccggg tcctccagga cggccaggcc gtgccgccgt 200

 gtgccctccg ccgctcgccc gcgcgccgcg cgctccccgc ctgcgcccag 250

 cgccccgcgc ccgcgcccca gtcctcgggc ggtccatgct gcccctctgc 300

 ctcgtggccg ccctgctgct ggccgccggg cccgggccga gcctgggcga 350

 cgaagccatc cactgcccgc cctgctccga ggagaagctg gcgcgctgcc 400

 gcccccccgt gggctgcgag gagctggtgc gagaggcggg ctgcggctgt 450

 tgcgccactt gcgccctggg cttggggatg ccctgcgggg tgtacacccc 500

 ccgttgcggc tcgggcctgc gctgctaccc gccccgaggg gtggagaagc 550

 ccctgcacac actgatgcac gggcaaggcg tgtgcatgga gctggcggag 600

 atcgaggcca tccaggaaag cctgcagccc tctgacaagg acgagggtga 650

 ccaccccaac aacagcttca gcccctgtag cgcccatgac cgcaggtgcc 700

 tgcagaagca cttcgccaaa attcgagacc ggagcaccag tgggggcaag 750

 atgaaggtca atggggcgcc ccgggaggat gcccggcctg tgccccaggg 800

 ctcctgccag agcgagctgc accgggcgct ggagcggctg gccgcttcac 850

 agagccgcac ccacgaggac ctctacttca tccccatccc caactgcgac 900

 cgcaacggca acttccaccc caagcagtgt cacccagctc tggatgggca 950

 gcgtggcaag tgctggtgtg tggaccggaa gacgggggtg aagcttccgg 1000

 ggggcctgga gccaaagggg gagctggact gccaccagct ggctgacagc 1050

 tttcgagagt gaggcctgcc agcaggccag ggactcagcg tcccctgcta 1100

 ctcctgtgct ctggaggctg cagagctgac ccagagtgga gtctgagtct 1150

 gagtcctgtc tctgcctgcg gcccagaagt ttccctcaaa tgcgcgtgtg 1200

 cacgtgtgcg tgtgcgtgcg tgtgtgtgtg tttgtgagca tgggtgtgcc 1250

 cttggggtaa gccagagcct ggggtgttct ctttggtgtt acacagccca 1300

 agaggactga gactggcact tagcccaaga ggtctgagcc ctggtgtgtt 1350

 tccagatcga tcctggattc actcactcac tcattccttc actcatccag 1400

 ccacctaaaa acatttactg accatgtact acgtgccagc tctagttttc 1450

 agccttggga ggttttattc tgacttcctc tgattttggc atgtggagac 1500

 actcctataa ggagagttca agcctgtggg agtagaaaaa tctcattccc 1550

 agagtcagag gagaagagac atgtaccttg accatcgtcc ttcctctcaa 1600

 gctagcccag agggtgggag cctaaggaag cgtggggtag cagatggagt 1650

 aatggtcacg aggtccagac ccactcccaa agctcagact tgccaggctc 1700

 cctttctctt cttccccagg tccttccttt aggtctggtt gttgcaccat 1750

 ctgcttggtt ggctggcagc tgagagccct gctgtgggag agcgaagggg 1800

 gtcaaaggaa gacttgaagc acagagggct agggaggtgg ggtacatttc 1850

 tctgagcagt cagggtggga agaaagaatg caagagtgga ctgaatgtgc 1900

 ctaatggaga agacccacgt gctaggggat gaggggcttc ctgggtcctg 1950

 ttcccctacc ccatttgtgg tcacagccat gaagtcaccg ggatgaacct 2000

 atccttccag tggctcgctc cctgtagctc tgcctccctc tccatatctc 2050

 cttcccctac acctccctcc ccacacctcc ctactcccct gggcatcttc 2100

 tggcttgact ggatggaagg agacttagga acctaccagt tggccatgat 2150

 gtcttttctt 2160

<210> 360
<211> 258
<212> PRT
<213> Homo sapien

<400> 360
 Met Leu Pro Leu Cys Leu Val Ala Ala Leu Leu Leu Ala Ala Gly
   1               5                  10                  15

 Pro Gly Pro Ser Leu Gly Asp Glu Ala Ile His Cys Pro Pro Cys
                  20                  25                  30

 Ser Glu Glu Lys Leu Ala Arg Cys Arg Pro Pro Val Gly Cys Glu
                  35                  40                  45

 Glu Leu Val Arg Glu Ala Gly Cys Gly Cys Cys Ala Thr Cys Ala
                  50                  55                  60

 Leu Gly Leu Gly Met Pro Cys Gly Val Tyr Thr Pro Arg Cys Gly
                  65                  70                  75

 Ser Gly Leu Arg Cys Tyr Pro Pro Arg Gly Val Glu Lys Pro Leu
                  80                  85                  90

 His Thr Leu Met His Gly Gln Gly Val Cys Met Glu Leu Ala Glu
                  95                 100                 105

 Ile Glu Ala Ile Gln Glu Ser Leu Gln Pro Ser Asp Lys Asp Glu
                 110                 115                 120

 Gly Asp His Pro Asn Asn Ser Phe Ser Pro Cys Ser Ala His Asp
                 125                 130                 135

 Arg Arg Cys Leu Gln Lys His Phe Ala Lys Ile Arg Asp Arg Ser
                 140                 145                 150

 Thr Ser Gly Gly Lys Met Lys Val Asn Gly Ala Pro Arg Glu Asp
                 155                 160                 165

 Ala Arg Pro Val Pro Gln Gly Ser Cys Gln Ser Glu Leu His Arg
                 170                 175                 180

 Ala Leu Glu Arg Leu Ala Ala Ser Gln Ser Arg Thr His Glu Asp
                 185                 190                 195

 Leu Tyr Phe Ile Pro Ile Pro Asn Cys Asp Arg Asn Gly Asn Phe
                 200                 205                 210

 His Pro Lys Gln Cys His Pro Ala Leu Asp Gly Gln Arg Gly Lys
                 215                 220                 225

 Cys Trp Cys Val Asp Arg Lys Thr Gly Val Lys Leu Pro Gly Gly
                 230                 235                 240

 Leu Glu Pro Lys Gly Glu Leu Asp Cys His Gln Leu Ala Asp Ser
                 245                 250                 255

 Phe Arg Glu


<210> 361
<211> 1238
<212> DNA
<213> Homo sapien

<400> 361
 cggcggagct ggtcccgttg tgctgcggcg ccgcgcggcc tgcagtcccg 50

 ggcccgcgcc ccgcgccgcc cgcccgcccg ccatggagcc cggccccgac 100

 ggccccgccg cctccggccc cgccgccatc cgcgagggct ggttccgcga 150

 gacctgcagc ctgtggcccg gccaggccct gtcgctgcag gtggagcagc 200

 tgctccacca ccggcgctcg cgctaccagg acatcctcgt cttccgcagt 250

 aagacctatg gcaacgtgct ggtgttggac ggtgtcatcc agtgcacgga 300

 gagagacgag ttctcctacc aggagatgat cgccaacctg cctctctgca 350

 gccaccccaa cccgcgaaag gtgctgatca tcgggggcgg agatggaggt 400

 gtcctgcggg aggtggtgaa gcacccctcc gtggagtccg tggtccagtg 450

 tgagatcgac gaggatgtca tccaagtctc caagaagttc ctgccaggca 500

 tggccattgg ctactctagc tcgaaggtga ccctacatgt gggtgacggt 550

 tttgagttca tgaaacagaa tcaggatgcc ttcgacgtga tcatcactga 600

 ctcctcagac cccatgggcc ccgccgaaag tctcttcaag gagtcctatt 650

 accagctcat gaagacagcc ctcaaggaag atggtgtcct ctgctgccag 700

 ggcgagtgcg agtggctgca cctggacctc atcaaggaga tgcggcagtt 750

 ctgccagtcc ctgttccccg tggtggccta tgcctactgc accatcccca 800

 cctaccccag cggccagatc ggcttcatgc tgtgcagcaa gaacccgagc 850

 acgaacttcc aggagccggt gcagccgctg acacagcagc aggtggcgca 900

 gatgcagctg aagtactaca actccgacgt gcaccgcgcc gcctttgtgc 950

 tgcccgagtt tgcccgcaag gccctgaatg atgtgagctg agcccaggcg 1000

 ccaccactga tgccacccag gacctcggac cttggagcct gcggggtgcc 1050

 tcggcccctc cagccccggg ccggacctcc tgctggctct cgcccaccaa 1100

 ccaagtgtta caagccccag aatgctgccc ggcctgccct gctgggcgga 1150

 ctgtctgtgt gtctgtctct ctggcgttcc acctccaagc ctataccagc 1200

 tgtgtacagc gccatctctc tgccttctgt tgcccccg 1238

<210> 362
<211> 302
<212> PRT
<213> Homo sapien

<400> 362
 Met Glu Pro Gly Pro Asp Gly Pro Ala Ala Ser Gly Pro Ala Ala
   1               5                  10                  15

 Ile Arg Glu Gly Trp Phe Arg Glu Thr Cys Ser Leu Trp Pro Gly
                  20                  25                  30

 Gln Ala Leu Ser Leu Gln Val Glu Gln Leu Leu His His Arg Arg
                  35                  40                  45

 Ser Arg Tyr Gln Asp Ile Leu Val Phe Arg Ser Lys Thr Tyr Gly
                  50                  55                  60

 Asn Val Leu Val Leu Asp Gly Val Ile Gln Cys Thr Glu Arg Asp
                  65                  70                  75

 Glu Phe Ser Tyr Gln Glu Met Ile Ala Asn Leu Pro Leu Cys Ser
                  80                  85                  90

 His Pro Asn Pro Arg Lys Val Leu Ile Ile Gly Gly Gly Asp Gly
                  95                 100                 105

 Gly Val Leu Arg Glu Val Val Lys His Pro Ser Val Glu Ser Val
                 110                 115                 120

 Val Gln Cys Glu Ile Asp Glu Asp Val Ile Gln Val Ser Lys Lys
                 125                 130                 135

 Phe Leu Pro Gly Met Ala Ile Gly Tyr Ser Ser Ser Lys Val Thr
                 140                 145                 150

 Leu His Val Gly Asp Gly Phe Glu Phe Met Lys Gln Asn Gln Asp
                 155                 160                 165

 Ala Phe Asp Val Ile Ile Thr Asp Ser Ser Asp Pro Met Gly Pro
                 170                 175                 180

 Ala Glu Ser Leu Phe Lys Glu Ser Tyr Tyr Gln Leu Met Lys Thr
                 185                 190                 195

 Ala Leu Lys Glu Asp Gly Val Leu Cys Cys Gln Gly Glu Cys Glu
                 200                 205                 210

 Trp Leu His Leu Asp Leu Ile Lys Glu Met Arg Gln Phe Cys Gln
                 215                 220                 225

 Ser Leu Phe Pro Val Val Ala Tyr Ala Tyr Cys Thr Ile Pro Thr
                 230                 235                 240

 Tyr Pro Ser Gly Gln Ile Gly Phe Met Leu Cys Ser Lys Asn Pro
                 245                 250                 255

 Ser Thr Asn Phe Gln Glu Pro Val Gln Pro Leu Thr Gln Gln Gln
                 260                 265                 270

 Val Ala Gln Met Gln Leu Lys Tyr Tyr Asn Ser Asp Val His Arg
                 275                 280                 285

 Ala Ala Phe Val Leu Pro Glu Phe Ala Arg Lys Ala Leu Asn Asp
                 290                 295                 300

 Val Ser


<210> 363
<211> 1643
<212> DNA
<213> Homo sapien

<400> 363
 caccaagggc tggccgcagc cactgtagct gagctcagag ccttctgtgt 50

 ggtttgcggg ggcaaggtca gctgccccct gccctctctc tggggctatt 100

 tgaggaatgc ggcctttttg cataagaaag gcttttctct acagtaactg 150

 tggtcgctga tcaatgacac cttcctggta acatttcata ttgctttttt 200

 ggagatactt tgacgaaggt aattgggact cccatcaagt ctccacacag 250

 ctagcagcca cgtggggcac ttctccagca tatgtaagtg gaactcagaa 300

 ggcaacattc cctgaacata ctcttccacc agaatctcct ctacagattt 350

 ttgctgcccc ttttaccagt ggctgaatct actttctctt atggatcgct 400

 tacacctgag acgaactaca gaacagcacg taccagaggt ggaagtccaa 450

 gtcaaacgca gaaggactgc ctcactgagc aaccaagagt gtcagttgta 500

 cccgaggcgt tctcagcagc agcaagtacc tgtggtggat ttccaggctg 550

 aactgaggca ggcattctta gctgagacac caagaggtgg ttaaagccat 600

 attggagtag cgaggaatct gattccaagc aaaaaccagg ctccatctac 650

 tctttgaagc ttctgcccag cttgcattgt ttctaggaga acctgcgtca 700

 tacctttatc tatagccttc ccctaggtct tcagaagcat caagttttaa 750

 ctgtggacat tggatttggt ggaacagcaa tcatgactgt tggcaagagt 800

 agcaagatgc tgcagcacat tgactataga atgagatgta tcctgcaaga 850

 tggccgaatc ttcattggca cctttaaggc ttttgacaag catatgaatt 900

 tgatcctctg tgattgtgat gagttcagaa agatcaagcc aaagaatgcg 950

 aagcaaccag agcgtgaaga aaagcgggtt ttgggtctgg tgttgctgcg 1000

 tggggagaac ttggtatcca tgactgtgga ggggccaccc cccaaagata 1050

 ctggcattgc tcgggtacca cttgctggag ctgctggagg ccctggggtt 1100

 ggtagggcag ctggtagagg agtaccagct ggtgtgccaa ttccccaggc 1150

 ccctgctgga ttggcaggcc ctgtccgagg agttggggga ccatcccagc 1200

 aggtaatgac tccacaggga agaggcactg tagcagctgc tgctgttgct 1250

 gcgactgcca gtattgctgg agccccaaca cagtacccac caggacgggg 1300

 cactccgccc ccacccgtcg gcagagcaac cccacctcca ggcattatgg 1350

 ctcctccacc tggtatgaga ccacccatgg gcccaccaat tgggcttccc 1400

 cctgctcgag ggacgccaat aggcatgccg cctccgggaa tgagaccccc 1450

 tccaccaggc attagaggtc cacctccccc aggaatgcgt ccaccaagac 1500

 cttagcatac tgttgatcca tctcagtcac tttttcccct gcaatgcgtc 1550

 ttgtgaaatt gtgtagagtg tttgtgagct ttttgttccc tcattctgca 1600

 ttaataatag ctaataataa atgcatagag caattaaact gtg 1643

<210> 364
<211> 240
<212> PRT
<213> Homo sapien

<400> 364
 Met Thr Val Gly Lys Ser Ser Lys Met Leu Gln His Ile Asp Tyr
   1               5                  10                  15

 Arg Met Arg Cys Ile Leu Gln Asp Gly Arg Ile Phe Ile Gly Thr
                  20                  25                  30

 Phe Lys Ala Phe Asp Lys His Met Asn Leu Ile Leu Cys Asp Cys
                  35                  40                  45

 Asp Glu Phe Arg Lys Ile Lys Pro Lys Asn Ala Lys Gln Pro Glu
                  50                  55                  60

 Arg Glu Glu Lys Arg Val Leu Gly Leu Val Leu Leu Arg Gly Glu
                  65                  70                  75

 Asn Leu Val Ser Met Thr Val Glu Gly Pro Pro Pro Lys Asp Thr
                  80                  85                  90

 Gly Ile Ala Arg Val Pro Leu Ala Gly Ala Ala Gly Gly Pro Gly
                  95                 100                 105

 Val Gly Arg Ala Ala Gly Arg Gly Val Pro Ala Gly Val Pro Ile
                 110                 115                 120

 Pro Gln Ala Pro Ala Gly Leu Ala Gly Pro Val Arg Gly Val Gly
                 125                 130                 135

 Gly Pro Ser Gln Gln Val Met Thr Pro Gln Gly Arg Gly Thr Val
                 140                 145                 150

 Ala Ala Ala Ala Val Ala Ala Thr Ala Ser Ile Ala Gly Ala Pro
                 155                 160                 165

 Thr Gln Tyr Pro Pro Gly Arg Gly Thr Pro Pro Pro Pro Val Gly
                 170                 175                 180

 Arg Ala Thr Pro Pro Pro Gly Ile Met Ala Pro Pro Pro Gly Met
                 185                 190                 195

 Arg Pro Pro Met Gly Pro Pro Ile Gly Leu Pro Pro Ala Arg Gly
                 200                 205                 210

 Thr Pro Ile Gly Met Pro Pro Pro Gly Met Arg Pro Pro Pro Pro
                 215                 220                 225

 Gly Ile Arg Gly Pro Pro Pro Pro Gly Met Arg Pro Pro Arg Pro
                 230                 235                 240

<210> 365
<211> 1746
<212> DNA
<213> Homo sapien

<400> 365
 gagcctgact tcagcgctcc cactctcggc cgacacccct catggccaac 50

 cgttacacca tggatctgac tgccatctac gagagcctcc tgtcgctgag 100

 ccctgacgtg cccgtgccat ccgaccatgg agggactgag tccagcccag 150

 gctggggctc ctcgggaccc tggagcctga gcccctccga ctccagcccg 200

 tctggggtca cctcccgcct gcctggccgc tccaccagcc tagtggaggg 250

 ccgcagctgt ggctgggtgc ccccaccccc tggcttcgca ccgctggctc 300

 cccgcctggg ccctgagctg tcaccctcac ccacttcgcc cactgcaacc 350

 tccaccaccc cctcgcgcta caagactgag ctatgtcgga ccttctcaga 400

 gagtgggcgc tgccgctacg gggccaagtg ccagtttgcc catggcctgg 450

 gcgagctgcg ccaggccaat cgccacccca aatacaagac ggaactctgt 500

 cacaagttct acctccaggg ccgctgcccc tacggctctc gctgccactt 550

 catccacaac cctagcgaag acctggcggc cccgggccac cctcctgtgc 600

 ttcgccagag catcagcttc tccggcctgc cctctggccg ccggacctca 650

 ccaccaccac caggcctggc cggcccttcc ctgtcctcca gctccttctc 700

 gccctccagc tccccaccac cacctgggga ccttccactg tcaccctctg 750

 ccttctctgc tgcccctggc acccccctgg ctcgaagaga ccccacccca 800

 gtctgttgcc cctcctgccg aagggccact cctatcagcg tctgggggcc 850

 cttgggtggc ctggttcgga ccccctctgt acagtccctg ggatccgacc 900

 ctgatgaata tgccagcagc ggcagcagcc tggggggctc tgactctccc 950

 gtcttcgagg cgggagtttt tgcaccaccc cagcccgtgg cagccccccg 1000

 gcgactcccc atcttcaatc gcatctctgt ttctgagtga caaagtgact 1050

 gcccggtcag atcagctgga tctcagcggg gagccacgtc tcttgcactg 1100

 tggtctctgc atggacccca gggctgtggg gacttggggg acagtaatca 1150

 agtaatcccc ttttccagaa tgcattaacc cactcccctg acctcacgct 1200

 ggggcaggtc cccaagtgtg caagctcagt attcatgatg gtgggggatg 1250

 gagtgtcttc cgaggttctt gggggaaaaa aaattgtagc atatttaagg 1300

 gaggcaatga accctctccc ccacctcttc cctgcccaaa tctgtctcct 1350

 agaatcttat gtgctgtgaa taataggcct tcactgcccc tccagttttt 1400

 atagacctga ggttccagtg tctcctggta actggaacct ctcctgaggg 1450

 ggaatcctgg tgctcaaatt accctccaaa agcaagtagc caaagccgtt 1500

 gccaaacccc acccataaat caatgggccc tttatttatg acgactttat 1550

 ttattctaat atgattttat agtatttata tatattgggt cgtctgcttc 1600

 ccttgtattt ttcttccttt ttttgtaata ttgaaaacga cgatataatt 1650

 attataagta gactataata tatttagtaa tatatattat taccttaaaa 1700

 gtctattttt gtgttttggg catttttaaa taaacaatct gagtgt 1746

<210> 366
<211> 326
<212> PRT
<213> Homo sapien

<400> 366
 Met Asp Leu Thr Ala Ile Tyr Glu Ser Leu Leu Ser Leu Ser Pro
   1               5                  10                  15

 Asp Val Pro Val Pro Ser Asp His Gly Gly Thr Glu Ser Ser Pro
                  20                  25                  30

 Gly Trp Gly Ser Ser Gly Pro Trp Ser Leu Ser Pro Ser Asp Ser
                  35                  40                  45

 Ser Pro Ser Gly Val Thr Ser Arg Leu Pro Gly Arg Ser Thr Ser
                  50                  55                  60

 Leu Val Glu Gly Arg Ser Cys Gly Trp Val Pro Pro Pro Pro Gly
                  65                  70                  75

 Phe Ala Pro Leu Ala Pro Arg Leu Gly Pro Glu Leu Ser Pro Ser
                  80                  85                  90

 Pro Thr Ser Pro Thr Ala Thr Ser Thr Thr Pro Ser Arg Tyr Lys
                  95                 100                 105

 Thr Glu Leu Cys Arg Thr Phe Ser Glu Ser Gly Arg Cys Arg Tyr
                 110                 115                 120

 Gly Ala Lys Cys Gln Phe Ala His Gly Leu Gly Glu Leu Arg Gln
                 125                 130                 135

 Ala Asn Arg His Pro Lys Tyr Lys Thr Glu Leu Cys His Lys Phe
                 140                 145                 150

 Tyr Leu Gln Gly Arg Cys Pro Tyr Gly Ser Arg Cys His Phe Ile
                 155                 160                 165

 His Asn Pro Ser Glu Asp Leu Ala Ala Pro Gly His Pro Pro Val
                 170                 175                 180

 Leu Arg Gln Ser Ile Ser Phe Ser Gly Leu Pro Ser Gly Arg Arg
                 185                 190                 195

 Thr Ser Pro Pro Pro Pro Gly Leu Ala Gly Pro Ser Leu Ser Ser
                 200                 205                 210

 Ser Ser Phe Ser Pro Ser Ser Ser Pro Pro Pro Pro Gly Asp Leu
                 215                 220                 225

 Pro Leu Ser Pro Ser Ala Phe Ser Ala Ala Pro Gly Thr Pro Leu
                 230                 235                 240

 Ala Arg Arg Asp Pro Thr Pro Val Cys Cys Pro Ser Cys Arg Arg
                 245                 250                 255

 Ala Thr Pro Ile Ser Val Trp Gly Pro Leu Gly Gly Leu Val Arg
                 260                 265                 270

 Thr Pro Ser Val Gln Ser Leu Gly Ser Asp Pro Asp Glu Tyr Ala
                 275                 280                 285

 Ser Ser Gly Ser Ser Leu Gly Gly Ser Asp Ser Pro Val Phe Glu
                 290                 295                 300

 Ala Gly Val Phe Ala Pro Pro Gln Pro Val Ala Ala Pro Arg Arg
                 305                 310                 315

 Leu Pro Ile Phe Asn Arg Ile Ser Val Ser Glu
                 320                 325

<210> 367
<211> 3323
<212> DNA
<213> Homo sapien

<400> 367
 gatcacgaac cagtcaaaat cgtggtttat ttctgtaacg tgaagacttc 50

 tgctcttttt tctttgtttg tttttttcgt aaacatctgg gtgtatatca 100

 aacggcaaga tgtccagtaa tgtcccggcg gatatgataa atttgcgcct 150

 cattttggta agcggaaaaa caaaagagtt cctgttttct cctaacgatt 200

 ctgcttctga cattgcaaag catgtatatg acaattggcc aatggactgg 250

 gaagaagagc aggtcagcag tccaaatatt ctacgactta tttatcaagg 300

 acgatttcta catggaaatg tcacattagg agcattaaaa cttccttttg 350

 gcaaaacaac agtgatgcat ttggtggcca gagagacatt accagagcca 400

 aactctcaag gtcagaggaa tcgtgagaag actggagaga gtaattgttg 450

 tgtaatcctg taaacactgt ctgcctagtg tgatgtgata tagtctttgt 500

 ctttcatgct gctgggacag aaaagacccg acattgcttc agaaaccgtt 550

 cagaacagtc tgcctgtaaa cacatggaac tgaattacca catgaacact 600

 gtcatctttt ctcatgaaag taaaaagaac caagaacatt tttcactctg 650

 attttttatt tcttgtattt tttgttgagc tgttttaaca catattggtt 700

 tttgaatgca gtcaatctcc aggggaaaag ttaacaagtt atctttcgta 750

 gcagaaacca ttttgctgcc acaaaatttt catcatcaga actaataaat 800

 caagtgttcc aaatacaatt tgcactaaaa agattggcat tattttcctc 850

 atcagcagaa tttataacag tgtgtggtat ctagaaatac ttatatatac 900

 aattccacac tggaagacac tcagcaatta atgaagttaa ttactgggcc 950

 aacttgagag gaaaaaatgg aaaagaaact aaaatgttgg gtgaattcta 1000

 ccaaagtcag ccgtggtggc tgcactggca cagaatacta aactgagtgt 1050

 gactattttc actgcaacaa atgaaaaaac aaaatgtgcc tgtttaaagc 1100

 actcagtaga gggctgatga aactaatttt ttttccttta agacatgcac 1150

 tcttgagtcc tacagtaact gagtgtttgt ttagacagca caagaagggg 1200

 tgagagtgcg tctcctagcc ttaatgtggg agggtagttt cagtcactca 1250

 tcggctttca ttattgtgca gaaatattag aaaacctcat tgatcaattt 1300

 tatgtatttg aatatcagca aattgaaatt ttccataatt atcattaatt 1350

 tgtaaccaca tccagtgtca tgcttactcc ttagagttca gatgaattct 1400

 taaaattaaa aaaaaactcc atagtactaa ttttgtttct ttatatagtt 1450

 tgcgtttgat attagtgctt gcaattgtat taaagtcaaa agctgatttt 1500

 tatggcatac acaagaatgc cactttttct tttatttcat accaataatt 1550

 taaagattga tatgctaaaa acaatttgca cagcactaaa gcatgagcta 1600

 ctttcatcta aacctgtaaa aatatgaaag atttttatat tttttcactg 1650

 ggaagaaatt cttcctggat gaaattacaa atatgtgtag aatatattta 1700

 ataaaagact tataaaatac ctaactacag gacttaaaat atagattggc 1750

 gcgtagtata tagaacaata ttccatataa ataagtttag cctttataaa 1800

 aatgaagttg caggctgaca ttacattctg tacttactaa gtgtcaacag 1850

 cccttacaaa cattaaatgt aaatggtttc aaatggtcag cgttgtttaa 1900

 atgtaatcat gttattttat tcattgttaa tgctttgatg aaaaggcttt 1950

 atatgcagta gatctacgaa aatattgttc atactgatca gaattaaatt 2000

 tgtatagagc agagttttaa aatgaatgta aatagcacta aacgttttct 2050

 ttctgcaacc tgtacttaca gattcttcct gtaaactaaa taaaaaaaaa 2100

 atgatagtgc attttggtgg taattttaaa ggtcttgatt aggtcaataa 2150

 ttgtttaagc accgtctcat tcatgttttc tactttcatt tcttaagctt 2200

 ttaaaattca tttaattaat attctgttgt tgttttgggg agtattccca 2250

 atgtatcttt gatatttaac ctggttaatt tgtggacagt cacaacaatg 2300

 gatagaatta tgtagtctcc gttatcacta aaatgttatc ttcaagagat 2350

 gttaaatatt tatatgcttt gttgactagc tgaaatgtga attctgttag 2400

 tgttgactaa agaatctggt agttgcttaa ttgggcaatt aaacaattta 2450

 tggctctatt ttgtaaaaca aactactggt aattattttt aatacctatt 2500

 ttcattctga ttactctttt tttaagttaa agactatcag ttaattaaga 2550

 ttgagttttt atgatggtta aaaataattc tctattggtt tttcaatata 2600

 tttttctgtg tgttctcaga ttatatattt ccctcaattt agagtttgct 2650

 aagtgaaata aactggttca ctagtagaga aagaattacg tcgcttaata 2700

 cctaatatca tagttgtaca atatgaaaaa aaagaataaa aagtagcagt 2750

 aaaattatat actgaaaaca ccaaaaattt agatgcctta atagtatata 2800

 cgtgaaatac tcagctgtcc ctttaaaaat aattccttgg actgcctggt 2850

 ggttaaaata cgattcctca tatccaaggc tacttttgaa gatccctctg 2900

 ccaaaaatat agctcactta tctaaaggtg agagctgcat agatccagta 2950

 atgtacataa agcctgaatg atgagcctat gtccctgcct aacgctggtg 3000

 tctcactcat ctcttttacc taaattgtcc tgaactttgt taagtgttct 3050

 ggacaaggcc aagcttttct ttattaaaac ctcagcatgt ctccctgatc 3100

 tgaactattt gctttctctt caagataagt tgtattttac catggaaaaa 3150

 tacagtatct aacattacca ttcacgttaa atgaagtttc ctcataacat 3200

 ttatctttag ttttatgaag tcatcgtgac caatgttaca gtaatttctg 3250

 ttagctgatt gtggtaaaca atgtttaatg tgaaaagaaa ttaaaacttt 3300

 cttcatctgt tgtaaaaaaa aaa 3323

<210> 368
<211> 117
<212> PRT
<213> Homo sapien

<400> 368
 Met Ser Ser Asn Val Pro Ala Asp Met Ile Asn Leu Arg Leu Ile
   1               5                  10                  15

 Leu Val Ser Gly Lys Thr Lys Glu Phe Leu Phe Ser Pro Asn Asp
                  20                  25                  30

 Ser Ala Ser Asp Ile Ala Lys His Val Tyr Asp Asn Trp Pro Met
                  35                  40                  45

 Asp Trp Glu Glu Glu Gln Val Ser Ser Pro Asn Ile Leu Arg Leu
                  50                  55                  60

 Ile Tyr Gln Gly Arg Phe Leu His Gly Asn Val Thr Leu Gly Ala
                  65                  70                  75

 Leu Lys Leu Pro Phe Gly Lys Thr Thr Val Met His Leu Val Ala
                  80                  85                  90

 Arg Glu Thr Leu Pro Glu Pro Asn Ser Gln Gly Gln Arg Asn Arg
                  95                 100                 105

 Glu Lys Thr Gly Glu Ser Asn Cys Cys Val Ile Leu
                 110                 115

<210> 369
<211> 3323
<212> DNA
<213> Homo sapien

<400> 369
 gatcacgaac cagtcaaaat cgtggtttat ttctgtaacg tgaagacttc 50

 tgctcttttt tctttgtttg tttttttcgt aaacatctgg gtgtatatca 100

 aacggcaaga tgtccagtaa tgtcccggcg gatatgataa atttgcgcct 150

 cattttggta agcggaaaaa caaaagagtt cctgttttct cctaacgatt 200

 ctgcttctga cattgcaaag catgtatatg acaattggcc aatggactgg 250

 gaagaagagc aggtcagcag tccaaatatt ctacgactta tttatcaagg 300

 acgatttcta catggaaatg tcacattagg agcattaaaa cttccttttg 350

 gcaaaacaac agtgatgcat ttggtggcca gagagacatt accagagcca 400

 aactctcaag gtcagaggaa tcgtgagaag actggagaga gtaattgttg 450

 tgtaatcctg taaacactgt ctgcctagtg tgatgtgata tagtctttgt 500

 ctttcatgct gctgggacag aaaagacccg acattgcttc agaaaccgtt 550

 cagaacagtc tgcctgtaaa cacatggaac tgaattacca catgaacact 600

 gtcatctttt ctcatgaaag taaaaagaac caagaacatt tttcactctg 650

 attttttatt tcttgtattt tttgttgagc tgttttaaca catattggtt 700

 tttgaatgca gtcaatctcc aggggaaaag ttaacaagtt atctttcgta 750

 gcagaaacca ttttgctgcc acaaaatttt catcatcaga actaataaat 800

 caagtgttcc aaatacaatt tgcactaaaa agattggcat tattttcctc 850

 atcagcagaa tttataacag tgtgtggtat ctagaaatac ttatatatac 900

 aattccacac tggaagacac tcagcaatta atgaagttaa ttactgggcc 950

 aacttgagag gaaaaaatgg aaaagaaact aaaatgttgg gtgaattcta 1000

 ccaaagtcag ccgtggtggc tgcactggca cagaatacta aactgagtgt 1050

 gactattttc actgcaacaa atgaaaaaac aaaatgtgcc tgtttaaagc 1100

 actcagtaga gggctgatga aactaatttt ttttccttta agacatgcac 1150

 tcttgagtcc tacagtaact gagtgtttgt ttagacagca caagaagggg 1200

 tgagagtgcg tctcctagcc ttaatgtggg agggtagttt cagtcactca 1250

 tcggctttca ttattgtgca gaaatattag aaaacctcat tgatcaattt 1300

 tatgtatttg aatatcagca aattgaaatt ttccataatt atcattaatt 1350

 tgtaaccaca tccagtgtca tgcttactcc ttagagttca gatgaattct 1400

 taaaattaaa aaaaaactcc atagtactaa ttttgtttct ttatatagtt 1450

 tgcgtttgat attagtgctt gcaattgtat taaagtcaaa agctgatttt 1500

 tatggcatac acaagaatgc cactttttct tttatttcat accaataatt 1550

 taaagattga tatgctaaaa acaatttgca cagcactaaa gcatgagcta 1600

 ctttcatcta aacctgtaaa aatatgaaag atttttatat tttttcactg 1650

 ggaagaaatt cttcctggat gaaattacaa atatgtgtag aatatattta 1700

 ataaaagact tataaaatac ctaactacag gacttaaaat atagattggc 1750

 gcgtagtata tagaacaata ttccatataa ataagtttag cctttataaa 1800

 aatgaagttg caggctgaca ttacattctg tacttactaa gtgtcaacag 1850

 cccttacaaa cattaaatgt aaatggtttc aaatggtcag cgttgtttaa 1900

 atgtaatcat gttattttat tcattgttaa tgctttgatg aaaaggcttt 1950

 atatgcagta gatctacgaa aatattgttc atactgatca gaattaaatt 2000

 tgtatagagc agagttttaa aatgaatgta aatagcacta aacgttttct 2050

 ttctgcaacc tgtacttaca gattcttcct gtaaactaaa taaaaaaaaa 2100

 atgatagtgc attttggtgg taattttaaa ggtcttgatt aggtcaataa 2150

 ttgtttaagc accgtctcat tcatgttttc tactttcatt tcttaagctt 2200

 ttaaaattca tttaattaat attctgttgt tgttttgggg agtattccca 2250

 atgtatcttt gatatttaac ctggttaatt tgtggacagt cacaacaatg 2300

 gatagaatta tgtagtctcc gttatcacta aaatgttatc ttcaagagat 2350

 gttaaatatt tatatgcttt gttgactagc tgaaatgtga attctgttag 2400

 tgttgactaa agaatctggt agttgcttaa ttgggcaatt aaacaattta 2450

 tggctctatt ttgtaaaaca aactactggt aattattttt aatacctatt 2500

 ttcattctga ttactctttt tttaagttaa agactatcag ttaattaaga 2550

 ttgagttttt atgatggtta aaaataattc tctattggtt tttcaatata 2600

 tttttctgtg tgttctcaga ttatatattt ccctcaattt agagtttgct 2650

 aagtgaaata aactggttca ctagtagaga aagaattacg tcgcttaata 2700

 cctaatatca tagttgtaca atatgaaaaa aaagaataaa aagtagcagt 2750

 aaaattatat actgaaaaca ccaaaaattt agatgcctta atagtatata 2800

 cgtgaaatac tcagctgtcc ctttaaaaat aattccttgg actgcctggt 2850

 ggttaaaata cgattcctca tatccaaggc tacttttgaa gatccctctg 2900

 ccaaaaatat agctcactta tctaaaggtg agagctgcat agatccagta 2950

 atgtacataa agcctgaatg atgagcctat gtccctgcct aacgctggtg 3000

 tctcactcat ctcttttacc taaattgtcc tgaactttgt taagtgttct 3050

 ggacaaggcc aagcttttct ttattaaaac ctcagcatgt ctccctgatc 3100

 tgaactattt gctttctctt caagataagt tgtattttac catggaaaaa 3150

 tacagtatct aacattacca ttcacgttaa atgaagtttc ctcataacat 3200

 ttatctttag ttttatgaag tcatcgtgac caatgttaca gtaatttctg 3250

 ttagctgatt gtggtaaaca atgtttaatg tgaaaagaaa ttaaaacttt 3300

 cttcatctgt tgtaaaaaaa aaa 3323

<210> 370
<211> 117
<212> PRT
<213> Homo sapien

<400> 370
 Met Ser Ser Asn Val Pro Ala Asp Met Ile Asn Leu Arg Leu Ile
   1               5                  10                  15

 Leu Val Ser Gly Lys Thr Lys Glu Phe Leu Phe Ser Pro Asn Asp
                  20                  25                  30

 Ser Ala Ser Asp Ile Ala Lys His Val Tyr Asp Asn Trp Pro Met
                  35                  40                  45

 Asp Trp Glu Glu Glu Gln Val Ser Ser Pro Asn Ile Leu Arg Leu
                  50                  55                  60

 Ile Tyr Gln Gly Arg Phe Leu His Gly Asn Val Thr Leu Gly Ala
                  65                  70                  75

 Leu Lys Leu Pro Phe Gly Lys Thr Thr Val Met His Leu Val Ala
                  80                  85                  90

 Arg Glu Thr Leu Pro Glu Pro Asn Ser Gln Gly Gln Arg Asn Arg
                  95                 100                 105

 Glu Lys Thr Gly Glu Ser Asn Cys Cys Val Ile Leu
                 110                 115

<210> 371
<211> 3003
<212> DNA
<213> Homo sapien

<400> 371
 ctagttctag atccggcgag tagctggcgg tcccgggtgc tgctggttag 50

 tgtgctctga gggagggtcc gagccagccg ctgttttgcc ggaggagccc 100

 ctcaggccgt agtaagcatt aataatgtct ttcatctttg agtggatcta 150

 caatggcttc agcagtgtgc tccagttcct aggactgtac aagaaatctg 200

 gaaaacttgt attcttaggt ttggataatg caggcaaaac cactcttctt 250

 cacatgctca aagatgacag attgggccaa catgttccaa cactacatcc 300

 gacatcagaa gagctaacaa ttgctggaat gacctttaca acttttgatc 350

 ttggtgggca cgagcaagca cgtcgcgttt ggaaaaatta tctcccagca 400

 attaatggga ttgtctttct ggtggactgt gcagatcatt ctcgcctcgt 450

 ggaatccaaa gttgagctta atgctttaat gactgatgaa acaatatcca 500

 atgtgccaat ccttatcttg ggtaacaaaa ttgacagaac agatgcaatc 550

 agtgaagaaa aactccgtga gatatttggg ctttatggac agaccacagg 600

 aaaggggaat gtgaccctga aggagctgaa tgctcgcccc atggaagtgt 650

 tcatgtgcag tgtgctcaag aggcaaggtt acggcgaggg tttccgctgg 700

 ctctcccagt atattgactg atgtttggac ggtgaaaata aaagagtttt 750

 acttctctgg actgatccta ttcacagctt cctcatgaac ttttctaata 800

 gaacaaggaa agctctccaa ccatgtctgg cgttgagaag ccaagagtct 850

 ctgtcaactc tctcattgcc cagtggtgac atgtgctctt ctccacactg 900

 ttgggaggta atgctgcccc acgtgctggt gcaggtcagt atcctgggac 950

 ttggaagctg gcaggatttg ccgggtaaag ctgtatgcca tcatggggca 1000

 cctgaaaaga aaaacacgtc tcaccactgt ggttgattca aaagaaagtg 1050

 attctatttt ttaaagaaag cgttgttaat gtaattggta tccctcctaa 1100

 ctttttgagt tcacaattta cttggtccag agttttctat tctttttttt 1150

 ttttaaacta atgaatgaca tttagatact tcataaaatt atgaacagat 1200

 atggaggcca gagctcattt gggtaaactt actcctgctg agttagcagg 1250

 ttggtgagag aagctcccct gagctcacct gtctctctga ctgccttgga 1300

 gtaggtggca taaccttgtg cacagagaac tagaaaaggg gcagaacccc 1350

 ggccttgcag ttgtggcagg tttccactgt ggtaagctag gttcattcct 1400

 catcaaggaa tgtgtagcag attgttcact gtggaggagt taattataga 1450

 atgggttatt gttgttattc ttactcatga agttacagat tttagccagt 1500

 ctttgctttt atacttttgt gaaatttaat ttctctctat agcaccttcc 1550

 tttttcgttt tcagttatca aaagtgactt tgacctcata aaagagttga 1600

 gaacatctct cgtgtcacat actgcaggtg catcagttac ttttgcacag 1650

 attctggggg acatttttct gaataggaag acaggacaaa gttaacagct 1700

 taagggctct taattctgtg agttgaggac ttaaaagtat tgtagcattt 1750

 gtttggatcc atgaaaaatg tattcagtgg gctttaaaat ttccatttgc 1800

 agaatttggt ctctcaggct gtttgggagc tctttttttt acattttttc 1850

 tcctttgaca cctattttat tggtgtttaa agtaaaggtt aacatctgta 1900

 gcttttccag gttttttttt tttttttttt gatatgaaat tgtctttctc 1950

 cattgcagaa ataagctagg gaaacactaa cccaaaaact ttctgtagag 2000

 ctgttccttt ggaggcagca tcacttattg gcagtaaaga ctcagtataa 2050

 aagcaccagc atccctactt gggtgatggg gattaatttt atagcattcc 2100

 attttcctag tgccacatgt gaaattggat tttgatgatc ttaatctata 2150

 ttctaccctt ataataaaag atcaaaagat atatctccta tgaacagatt 2200

 ggagatagga gatgaaaagt tgggaggatg tctttattct aatgtgaggg 2250

 tagggaaaat gtggataaca ttactggggt gaaggaggca ttgttcttta 2300

 gttggagttc tcatttttat tctccagtac tgacttgtgg ggaaagcata 2350

 ctttttcact gccaggtact gaatgcagag gctcagtgaa gtatatatgt 2400

 gggaagtgca tgcatttcgt ttattagcaa acatagctgg attaagacaa 2450

 agttgttggt ttggaaaggg gttaaagcct taagtgaaca aatctagcta 2500

 acagtgaatg aactaggtaa tataacttgc atatttttaa tttcctttgg 2550

 ttaaaggtcc cccatacttc tctgttcgga gacatgagaa gtatgattac 2600

 ttcagtgtta gttttcttaa tttttttttt cccctatttg tcccttgtca 2650

 ctttgttgca agctagaaat ctgtgggtta tacatagggc agctctttgt 2700

 gaaagtggtt tattccactg gagaaagggg attgaaaatc agttagaacc 2750

 aatgtatttc ttgccccacg gaacactatt cctataagat agctgaaaga 2800

 agctgctgtg aggagctcag ctccaaacac aggatcagca ccttgtatag 2850

 gaattcccat gaattatgac ttctcattct gttttatcag agtgcatata 2900

 tgtcctactt caggaaaagt aaaacagtca tttacgaaag aaagtcaatc 2950

 tgtatcctaa gcattttaat aaaaagttaa aacaaaaaaa aaaaaaaaaa 3000

 aaa 3003

<210> 372
<211> 198
<212> PRT
<213> Homo sapien

<400> 372
 Met Ser Phe Ile Phe Glu Trp Ile Tyr Asn Gly Phe Ser Ser Val
   1               5                  10                  15

 Leu Gln Phe Leu Gly Leu Tyr Lys Lys Ser Gly Lys Leu Val Phe
                  20                  25                  30

 Leu Gly Leu Asp Asn Ala Gly Lys Thr Thr Leu Leu His Met Leu
                  35                  40                  45

 Lys Asp Asp Arg Leu Gly Gln His Val Pro Thr Leu His Pro Thr
                  50                  55                  60

 Ser Glu Glu Leu Thr Ile Ala Gly Met Thr Phe Thr Thr Phe Asp
                  65                  70                  75

 Leu Gly Gly His Glu Gln Ala Arg Arg Val Trp Lys Asn Tyr Leu
                  80                  85                  90

 Pro Ala Ile Asn Gly Ile Val Phe Leu Val Asp Cys Ala Asp His
                  95                 100                 105

 Ser Arg Leu Val Glu Ser Lys Val Glu Leu Asn Ala Leu Met Thr
                 110                 115                 120

 Asp Glu Thr Ile Ser Asn Val Pro Ile Leu Ile Leu Gly Asn Lys
                 125                 130                 135

 Ile Asp Arg Thr Asp Ala Ile Ser Glu Glu Lys Leu Arg Glu Ile
                 140                 145                 150

 Phe Gly Leu Tyr Gly Gln Thr Thr Gly Lys Gly Asn Val Thr Leu
                 155                 160                 165

 Lys Glu Leu Asn Ala Arg Pro Met Glu Val Phe Met Cys Ser Val
                 170                 175                 180

 Leu Lys Arg Gln Gly Tyr Gly Glu Gly Phe Arg Trp Leu Ser Gln
                 185                 190                 195

 Tyr Ile Asp


<210> 373
<211> 1807
<212> DNA
<213> Homo sapien

<400> 373
 ctctgagtca ccaacctgag gctgccccgg ccgcctgcgc acccggcagc 50

 accatgacag atcaggcctt tgtgacacta accacaaacg atgcctacgc 100

 caaaggtgcc ctggtcctgg gatcatctct gaaacagcac aggaccacca 150

 ggaggctggt cgtgctcgcc acccctcagg tctcagactc catgagaaaa 200

 gttttagaga cagtctttga tgaagtcatc atggtagatg tcttggacag 250

 tggcgattct gctcatctaa ccttaatgaa gaggccagag ttgggtgtca 300

 cgctgacaaa gctccactgc tggtcgctta cacagtattc aaaatgtgta 350

 ttcatggatg cagatactct ggtcctagca aatattgatg atctttttga 400

 cagagaagaa ttgtcagcag caccagaccc agggtggcct gactgcttca 450

 attccggagt cttcgtttat cagccttcag ttgaaacata caatcagctg 500

 ttgcatcttg cttctgagca aggtagtttt gatggtgggg accaaggcat 550

 actgaacaca ttttttagca gctgggcaac aacagatatc agaaaacacc 600

 tgccgtttat ttataaccta agcagcatct ctatatactc ctacctcccg 650

 gcatttaaag tgtttggtgc aagtgccaaa gttgtgcatt tcctgggacg 700

 agtcaaacca tggaattata cttatgatcc caaaacaaaa agtgtcaaaa 750

 gtgaggccca tgatcccaac atgactcatc cagagtttct catcctgtgg 800

 tggaacatct ttaccaccaa cgttttacct ctgcttcaac aatttggcct 850

 tgtcaaagac acctgctcat atgtaaatgt gctttcagac ttggtctata 900

 cactggcttt ctcttgtggc ttctgtagaa aggaagatgt ctcaggagcc 950

 atatcacatc tgtcccttgg ggagatccca gctatggcac agccgtttgt 1000

 atcctcggaa gaacggaagg aacgatggga acagggccag gctgattata 1050

 tgggagcaga ttcctttgac aacatcaaga ggaaacttga cacttacctc 1100

 cagtagaaac actgcatttt tctgtgaaca catccacttc acaagccttg 1150

 tttctgatac ttagtatcta gagctgggtt gagaaaagtc tgttacagtt 1200

 gctagaggtt ttcattaaaa cttatcagat gagaggcttt tttaggataa 1250

 gaggtgagaa ctgggcaaaa gttgtgaagc agcaattctg ttatatggac 1300

 agtgttctgc tttttaatcc tatttagctt gtttcagaaa ttctcacttt 1350

 tgttgactgc caacatacaa agtaagggaa actcaagata ttaagatggc 1400

 tgtatcagtt cttaaaatct gcagagcctg gttcaaaatc agtcactccc 1450

 ttcagaagca gacatggcat ctgttccttg cttgcttgtt ggttgtgtac 1500

 ctttcacgag acctgaattt tagaattgcc cagtgctgcc agagtgagtg 1550

 agtgtaattc tcctttcagg taaagatagg ctatctcaac actgctgagt 1600

 gattcataaa catatcaacc aatagcatta acccatttta tttcctgtcc 1650

 ttagtgtctg aagatgctca ccagttttct gtgtacagta aggcagcatg 1700

 ctaaaatgct tttgttcagt tctggatatt tgaaaatagc agtgtgttct 1750

 ctgatggtta cctgcagtgg caccctgtac aaaaaataaa agacttattg 1800

 gtgtaaa 1807

<210> 374
<211> 350
<212> PRT
<213> Homo sapien

<400> 374
 Met Thr Asp Gln Ala Phe Val Thr Leu Thr Thr Asn Asp Ala Tyr
   1               5                  10                  15

 Ala Lys Gly Ala Leu Val Leu Gly Ser Ser Leu Lys Gln His Arg
                  20                  25                  30

 Thr Thr Arg Arg Leu Val Val Leu Ala Thr Pro Gln Val Ser Asp
                  35                  40                  45

 Ser Met Arg Lys Val Leu Glu Thr Val Phe Asp Glu Val Ile Met
                  50                  55                  60

 Val Asp Val Leu Asp Ser Gly Asp Ser Ala His Leu Thr Leu Met
                  65                  70                  75

 Lys Arg Pro Glu Leu Gly Val Thr Leu Thr Lys Leu His Cys Trp
                  80                  85                  90

 Ser Leu Thr Gln Tyr Ser Lys Cys Val Phe Met Asp Ala Asp Thr
                  95                 100                 105

 Leu Val Leu Ala Asn Ile Asp Asp Leu Phe Asp Arg Glu Glu Leu
                 110                 115                 120

 Ser Ala Ala Pro Asp Pro Gly Trp Pro Asp Cys Phe Asn Ser Gly
                 125                 130                 135

 Val Phe Val Tyr Gln Pro Ser Val Glu Thr Tyr Asn Gln Leu Leu
                 140                 145                 150

 His Leu Ala Ser Glu Gln Gly Ser Phe Asp Gly Gly Asp Gln Gly
                 155                 160                 165

 Ile Leu Asn Thr Phe Phe Ser Ser Trp Ala Thr Thr Asp Ile Arg
                 170                 175                 180

 Lys His Leu Pro Phe Ile Tyr Asn Leu Ser Ser Ile Ser Ile Tyr
                 185                 190                 195

 Ser Tyr Leu Pro Ala Phe Lys Val Phe Gly Ala Ser Ala Lys Val
                 200                 205                 210

 Val His Phe Leu Gly Arg Val Lys Pro Trp Asn Tyr Thr Tyr Asp
                 215                 220                 225

 Pro Lys Thr Lys Ser Val Lys Ser Glu Ala His Asp Pro Asn Met
                 230                 235                 240

 Thr His Pro Glu Phe Leu Ile Leu Trp Trp Asn Ile Phe Thr Thr
                 245                 250                 255

 Asn Val Leu Pro Leu Leu Gln Gln Phe Gly Leu Val Lys Asp Thr
                 260                 265                 270

 Cys Ser Tyr Val Asn Val Leu Ser Asp Leu Val Tyr Thr Leu Ala
                 275                 280                 285

 Phe Ser Cys Gly Phe Cys Arg Lys Glu Asp Val Ser Gly Ala Ile
                 290                 295                 300

 Ser His Leu Ser Leu Gly Glu Ile Pro Ala Met Ala Gln Pro Phe
                 305                 310                 315

 Val Ser Ser Glu Glu Arg Lys Glu Arg Trp Glu Gln Gly Gln Ala
                 320                 325                 330

 Asp Tyr Met Gly Ala Asp Ser Phe Asp Asn Ile Lys Arg Lys Leu
                 335                 340                 345

 Asp Thr Tyr Leu Gln
                 350

<210> 375
<211> 3061
<212> DNA
<213> Homo sapien

<400> 375
 cggcacgagg cgactttggt ggaggtagtt ctttggcagc gggcatggcg 50

 ggtaccgtgg tgctggacga tgtggagctg cgggaggctc agagagatta 100

 cctggacttc ctggacgacg aggaagacca gggaatttat cagagcaaag 150

 ttcgggagct gatcagtgac aaccaatacc ggctgattgt caatgtgaat 200

 gacctgcgca ggaaaaacga gaagagggct aaccggcttc tgaacaatgc 250

 ctttgaggag ctggttgcct tccagcgggc cttaaaggat tttgtggcct 300

 ccattgatgc tacctatgcc aagcagtatg aggagttcta cgtaggactg 350

 gaaggcagct ttggctccaa gcacgtctcc ccgcggactc ttacctcctg 400

 cttcctcagc tgtgtggtct gtgtggaggg cattgtcact aaatgttctc 450

 tagttcgtcc caaagtcgtc cgcagtgtcc actactgtcc tgctactaag 500

 aagaccatag agcgacgtta ttctgatctc accaccctgg tggcctttcc 550

 ctccagctct gtctatccta ccaaggatga ggagaacaat ccccttgaga 600

 cagaatatgg cctttctgtc tacaaggatc accagaccat caccatccag 650

 gagatgccgg agaaggcccc agccggccag ctcccccgct ctgtggacgt 700

 cattctggat gatgacttgg tggataaagc gaagcctggt gaccgggttc 750

 aggtggtggg aacctaccgt tgccttcctg gaaagaaggg aggctacacc 800

 tctgggacct tcaggactgt cctgattgcc tgtaatgtta agcagatgag 850

 caaggatgct cagccctctt tctctgctga ggatatagcc aagatcaaga 900

 agttcagtaa aacccgatcc aaggatatct ttgaccagct ggccaagtca 950

 ttggccccaa gtatccatgg gcatgactat gtcaagaaag caatcctctg 1000

 cttgctcttg ggaggggtgg aacgagacct agaaaatggc agccacatcc 1050

 gtggggacat caatattctt ctaataggag acccatccgt tgccaagtct 1100

 cagcttctgc ggtatgtgct ttgcactgca ccccgagcta tccccaccac 1150

 tggccggggc tcctctggag tgggtctgac ggctgctgtc accacagacc 1200

 aggaaacagg agagcgccgt ctggaagcag gggccatggt cctggctgac 1250

 cgaggcgtgg tttgcattga tgaatttgac aaaatgtctg acatggatcg 1300

 cacagccatc catgaagtga tggagcaggg tcgagtgacc attgccaagg 1350

 ctggcatcca tgctcggctg aatgcccgct gcagtgtttt ggcagctgcc 1400

 aaccctgtct acggcaggta tgaccagtat aagactccaa tggagaacat 1450

 tgggctacag gactcactgc tgtcacgatt tgacttgctc ttcatcatgc 1500

 tggatcagat ggatcctgag caggatcggg agatctcaga ccatgtcctt 1550

 cggatgcacc gttacagagc acctggggag caggatggcg atgctatgcc 1600

 cttgggtagt gctgtggata tcctggccac agatgatccc aactttagcc 1650

 aggaagatca gcaggacacc cagatttatg agaagcatga caaccttcta 1700

 catgggacca agaagaaaaa ggagaagatg gtgagtgcag cattcatgaa 1750

 gaagtacatc catgtggcca aaatcatcaa gcctgtcctg acacaggagt 1800

 cggccaccta cattgcagaa gagtattcac gcctgcgcag ccaggatagc 1850

 atgagctcag acaccgccag gacatctcca gttacagccc gaacactgga 1900

 aactctgatt cgactggcca cagcccatgc gaaggcccgc atgagcaaga 1950

 ctgtggacct gcaggatgca gaggaagctg tggagttggt ccagtatgct 2000

 tactttaaga aggttctgga gaaggagaag aaacgtaaga agcgaagtga 2050

 ggatgaatca gagacagaag atgaagagga gaaaagccaa gaggaccagg 2100

 agcagaagag gaagagaagg aagactcgcc agccagatgc caaagatggg 2150

 gattcatacg acccctatga cttcagtgac acagaggagg aaatgcctca 2200

 agtacacact ccaaagacgg cagactcaca ggagaccaag gaatcccaga 2250

 aagtggagtt gagtgaatcc aggttgaagg cattcaaggt ggccctcttg 2300

 gatgtgttcc gggaagctca tgcgcagtca atcggcatga atcgcctcac 2350

 agaatccatc aaccgggaca gcgaagagcc cttctcttca gttgagatcc 2400

 aggctgctct gagcaagatg caggatgaca atcaggtcat ggtgtctgag 2450

 ggcatcatct tcctcatctg aggaggcctc gtctctgaac ttgggttgtg 2500

 ccgagagagt ttgttctgtg tttcccaccc tctccctgac ccaagtcttt 2550

 gcctctactc ccttaacagt gttgaattca actgaaggcg aggaatgttg 2600

 gtgatgaagc tgagttcagg actcggtgga ccctttggga atgggtcatg 2650

 aaagctgcca tggggtgagg aaagaggaga cagtgggaga ggacaatgac 2700

 tattgcatct tcattgcaaa agcactggct catccgccct acttcccatc 2750

 ccacacaaac ccaattgtaa ataacatatg acttctgagt acttttgggg 2800

 gcacaactgt tttctgtttg ctgttttttt gttttgtttt ttttctccag 2850

 agcactttgg tctagactag gctttgggtg gttccaattg gtggagagaa 2900

 gctctgaggc acgtcatgca ggtcaagaaa gctttctttg cagtagcacc 2950

 agttaaggtg aatatgtatt gtatcacaaa acaaacccaa tatccagatg 3000

 aatatccgag atgttgaata aacttagcca tttcgtacaa aaaaaggggg 3050

 gcccggtaaa c 3061

<210> 376
<211> 808
<212> PRT
<213> Homo sapien

<400> 376
 Met Ala Gly Thr Val Val Leu Asp Asp Val Glu Leu Arg Glu Ala
   1               5                  10                  15

 Gln Arg Asp Tyr Leu Asp Phe Leu Asp Asp Glu Glu Asp Gln Gly
                  20                  25                  30

 Ile Tyr Gln Ser Lys Val Arg Glu Leu Ile Ser Asp Asn Gln Tyr
                  35                  40                  45

 Arg Leu Ile Val Asn Val Asn Asp Leu Arg Arg Lys Asn Glu Lys
                  50                  55                  60

 Arg Ala Asn Arg Leu Leu Asn Asn Ala Phe Glu Glu Leu Val Ala
                  65                  70                  75

 Phe Gln Arg Ala Leu Lys Asp Phe Val Ala Ser Ile Asp Ala Thr
                  80                  85                  90

 Tyr Ala Lys Gln Tyr Glu Glu Phe Tyr Val Gly Leu Glu Gly Ser
                  95                 100                 105

 Phe Gly Ser Lys His Val Ser Pro Arg Thr Leu Thr Ser Cys Phe
                 110                 115                 120

 Leu Ser Cys Val Val Cys Val Glu Gly Ile Val Thr Lys Cys Ser
                 125                 130                 135

 Leu Val Arg Pro Lys Val Val Arg Ser Val His Tyr Cys Pro Ala
                 140                 145                 150

 Thr Lys Lys Thr Ile Glu Arg Arg Tyr Ser Asp Leu Thr Thr Leu
                 155                 160                 165

 Val Ala Phe Pro Ser Ser Ser Val Tyr Pro Thr Lys Asp Glu Glu
                 170                 175                 180

 Asn Asn Pro Leu Glu Thr Glu Tyr Gly Leu Ser Val Tyr Lys Asp
                 185                 190                 195

 His Gln Thr Ile Thr Ile Gln Glu Met Pro Glu Lys Ala Pro Ala
                 200                 205                 210

 Gly Gln Leu Pro Arg Ser Val Asp Val Ile Leu Asp Asp Asp Leu
                 215                 220                 225

 Val Asp Lys Ala Lys Pro Gly Asp Arg Val Gln Val Val Gly Thr
                 230                 235                 240

 Tyr Arg Cys Leu Pro Gly Lys Lys Gly Gly Tyr Thr Ser Gly Thr
                 245                 250                 255

 Phe Arg Thr Val Leu Ile Ala Cys Asn Val Lys Gln Met Ser Lys
                 260                 265                 270

 Asp Ala Gln Pro Ser Phe Ser Ala Glu Asp Ile Ala Lys Ile Lys
                 275                 280                 285

 Lys Phe Ser Lys Thr Arg Ser Lys Asp Ile Phe Asp Gln Leu Ala
                 290                 295                 300

 Lys Ser Leu Ala Pro Ser Ile His Gly His Asp Tyr Val Lys Lys
                 305                 310                 315

 Ala Ile Leu Cys Leu Leu Leu Gly Gly Val Glu Arg Asp Leu Glu
                 320                 325                 330

 Asn Gly Ser His Ile Arg Gly Asp Ile Asn Ile Leu Leu Ile Gly
                 335                 340                 345

 Asp Pro Ser Val Ala Lys Ser Gln Leu Leu Arg Tyr Val Leu Cys
                 350                 355                 360

 Thr Ala Pro Arg Ala Ile Pro Thr Thr Gly Arg Gly Ser Ser Gly
                 365                 370                 375

 Val Gly Leu Thr Ala Ala Val Thr Thr Asp Gln Glu Thr Gly Glu
                 380                 385                 390

 Arg Arg Leu Glu Ala Gly Ala Met Val Leu Ala Asp Arg Gly Val
                 395                 400                 405

 Val Cys Ile Asp Glu Phe Asp Lys Met Ser Asp Met Asp Arg Thr
                 410                 415                 420

 Ala Ile His Glu Val Met Glu Gln Gly Arg Val Thr Ile Ala Lys
                 425                 430                 435

 Ala Gly Ile His Ala Arg Leu Asn Ala Arg Cys Ser Val Leu Ala
                 440                 445                 450

 Ala Ala Asn Pro Val Tyr Gly Arg Tyr Asp Gln Tyr Lys Thr Pro
                 455                 460                 465

 Met Glu Asn Ile Gly Leu Gln Asp Ser Leu Leu Ser Arg Phe Asp
                 470                 475                 480

 Leu Leu Phe Ile Met Leu Asp Gln Met Asp Pro Glu Gln Asp Arg
                 485                 490                 495

 Glu Ile Ser Asp His Val Leu Arg Met His Arg Tyr Arg Ala Pro
                 500                 505                 510

 Gly Glu Gln Asp Gly Asp Ala Met Pro Leu Gly Ser Ala Val Asp
                 515                 520                 525

 Ile Leu Ala Thr Asp Asp Pro Asn Phe Ser Gln Glu Asp Gln Gln
                 530                 535                 540

 Asp Thr Gln Ile Tyr Glu Lys His Asp Asn Leu Leu His Gly Thr
                 545                 550                 555

 Lys Lys Lys Lys Glu Lys Met Val Ser Ala Ala Phe Met Lys Lys
                 560                 565                 570

 Tyr Ile His Val Ala Lys Ile Ile Lys Pro Val Leu Thr Gln Glu
                 575                 580                 585

 Ser Ala Thr Tyr Ile Ala Glu Glu Tyr Ser Arg Leu Arg Ser Gln
                 590                 595                 600

 Asp Ser Met Ser Ser Asp Thr Ala Arg Thr Ser Pro Val Thr Ala
                 605                 610                 615

 Arg Thr Leu Glu Thr Leu Ile Arg Leu Ala Thr Ala His Ala Lys
                 620                 625                 630

 Ala Arg Met Ser Lys Thr Val Asp Leu Gln Asp Ala Glu Glu Ala
                 635                 640                 645

 Val Glu Leu Val Gln Tyr Ala Tyr Phe Lys Lys Val Leu Glu Lys
                 650                 655                 660

 Glu Lys Lys Arg Lys Lys Arg Ser Glu Asp Glu Ser Glu Thr Glu
                 665                 670                 675

 Asp Glu Glu Glu Lys Ser Gln Glu Asp Gln Glu Gln Lys Arg Lys
                 680                 685                 690

 Arg Arg Lys Thr Arg Gln Pro Asp Ala Lys Asp Gly Asp Ser Tyr
                 695                 700                 705

 Asp Pro Tyr Asp Phe Ser Asp Thr Glu Glu Glu Met Pro Gln Val
                 710                 715                 720

 His Thr Pro Lys Thr Ala Asp Ser Gln Glu Thr Lys Glu Ser Gln
                 725                 730                 735

 Lys Val Glu Leu Ser Glu Ser Arg Leu Lys Ala Phe Lys Val Ala
                 740                 745                 750

 Leu Leu Asp Val Phe Arg Glu Ala His Ala Gln Ser Ile Gly Met
                 755                 760                 765

 Asn Arg Leu Thr Glu Ser Ile Asn Arg Asp Ser Glu Glu Pro Phe
                 770                 775                 780

 Ser Ser Val Glu Ile Gln Ala Ala Leu Ser Lys Met Gln Asp Asp
                 785                 790                 795

 Asn Gln Val Met Val Ser Glu Gly Ile Ile Phe Leu Ile
                 800                 805

<210> 377
<211> 2159
<212> DNA
<213> Homo sapien

<400> 377
 tctttccgtc ccgggcagcc agcgccagtc ggagccagcg cgagcgccgc 50

 cgccatcact gccgctgcca agtcctccac ccgctgcccc cgccatgtct 100

 gctaccgctg ccacggcccc ccctgctgcc ccggctgggg agggtggtcc 150

 ccctgcaccc cctccaaacc tcaccagtaa caggagactg cagcagaccc 200

 aggcccaggt ggatgaggtg gtggacatca tgagggtgaa cgtggacaag 250

 gtcctggagc gagaccagaa gctgtcggag ctggacgacc gtgcagatgc 300

 actccaggcg ggggcctccc agtttgaaac aagcgcagcc aagctcaagc 350

 gcaaatactg gtggaaaaac ctcaagatga tgatcatctt gggagtgatt 400

 tgcgccatca tcctcatcat catcatagtt tacttcagct cttaaatccc 450

 cgaggagtct gccctgccta gagaagggcc tctcccccaa ccctcagccg 500

 ttcctccacc tctcagccat atctttcagc cccccctccc ctggatccgt 550

 gtgtgtgtgt gtccgtgtgt gtgtccccct gtaaatagcc agctgttatt 600

 tatacatata taatattata tatatttggt ctgtttgtag ttttattact 650

 agatgatttt tccggttgtc cttaacaccc cttcctgagg ttcccttcac 700

 ccctctctct tgccttcctt ccctttccct ttcttcctga ctagccccaa 750

 gtcccttcat ttgcatctgc tatgcaatag tccctctcct ttccttcttc 800

 ttccctcaga tttagctgat ccttcctccc accctggcct tcctttcctc 850

 tttcctcctc actctccccg tcatgctccc tctgccccgc cctcaaaaaa 900

 aaaaaaaaaa aaaaaaaaaa aaaaaaccac cagcacctgt ccaggcttcc 950

 ttaggtacat cttctttgta tccattggga ggctctgaga ctggccccac 1000

 ttggtcctaa aaatcccaag gtctttggga gcgtccagca tgttaattag 1050

 cgtatcatta catactgcta tccctttcca tttctttttg ttccatcact 1100

 cttctctcaa cctgtgtttc tttttttact gaggagttag tccccattag 1150

 ttcttgtatc acattttcat ttgcacgaca ttactcgcag gtggtgggga 1200

 gcctgggctt ttggggaacc aggctgctct ggtccccagc attgcctcct 1250

 cctagcccct ctagtccagt ttgcctccct taccctcatt ttccaaacct 1300

 cttgtaccct cctctccctc ccccagtggt atgtaagtgt cttgaagttc 1350

 agtatgttat gatggaccaa taattctgcc cttcgggttt ctccctacat 1400

 tcctgctccc cagttttcat gtggggtact caactgacat tcccatgggg 1450

 tttccctccc atctgcctga tccacctcct cctcccacca caagatcaat 1500

 tgttggccac aattgatctc ttgtagaggg gtggctacca gtgtgtgtgt 1550

 gggggtcatc actgccttgg ggaggagtgg ggcagggcag agaatccccc 1600

 caattcctgc ctgaaatctc tggcctcacc cctgctgggg gttggactga 1650

 aaaccctcct ccccaatttg gggggtgttg ccccatcact gcccagctcc 1700

 tctgactgcc ccccctgaat ttagggtggg ggtactagtc actgccaatg 1750

 tgtgtatggg acttgctgga aaacggggat gcttgcccct ctccaggact 1800

 attgagccca gagagagctg tcctctcatt gggtgaactg attgaggaag 1850

 ggtctattgt ctttttaaat ggcacaattt taagggtttg agggtacagt 1900

 cccttaacct gccacgggag ggggccccca aactttcttc ccccccacac 1950

 ttctggtttt ctgtgtggag ggggagcagg gatatctaag ctgtggtgtg 2000

 aaagggtagg agagatgctg gaggtggggg tgctgtgttc tagacccccc 2050

 atattatccc agtgtcccct gcccccctct tcccccaccc catgccccca 2100

 attctgtggc gcatccagat tgtgaaaatg tacaataaat gtgtaatgag 2150

 taaccaggt 2159

<210> 378
<211> 116
<212> PRT
<213> Homo sapien

<400> 378
 Met Ser Ala Thr Ala Ala Thr Ala Pro Pro Ala Ala Pro Ala Gly
   1               5                  10                  15

 Glu Gly Gly Pro Pro Ala Pro Pro Pro Asn Leu Thr Ser Asn Arg
                  20                  25                  30

 Arg Leu Gln Gln Thr Gln Ala Gln Val Asp Glu Val Val Asp Ile
                  35                  40                  45

 Met Arg Val Asn Val Asp Lys Val Leu Glu Arg Asp Gln Lys Leu
                  50                  55                  60

 Ser Glu Leu Asp Asp Arg Ala Asp Ala Leu Gln Ala Gly Ala Ser
                  65                  70                  75

 Gln Phe Glu Thr Ser Ala Ala Lys Leu Lys Arg Lys Tyr Trp Trp
                  80                  85                  90

 Lys Asn Leu Lys Met Met Ile Ile Leu Gly Val Ile Cys Ala Ile
                  95                 100                 105

 Ile Leu Ile Ile Ile Ile Val Tyr Phe Ser Ser
                 110                 115

<210> 379
<211> 4318
<212> DNA
<213> Homo sapien

<400> 379
 aagcggctcg ggctgcggct ggctcagagt gccgcggggg gcgtggggcg 50

 gtgctgagga gctgaagccg tggccagctc gactccggac agtccagcga 100

 gcagcacggc gggaaccggc agccggagca gtcccggagc agaagcagca 150

 gcagcagcag cagccctcgc cgttcgcgga gcgcagccga gccggccatg 200

 gcgttgtcga tgccgctgaa tgggctgaag gaggaggaca aagagcccct 250

 catcgagctc ttcgtcaagg ctggcagtga tggtgaaagc ataggaaact 300

 gccccttttc ccagaggctc ttcatgattc tttggctcaa aggagttgta 350

 tttagtgtga cgactgttga cctgaaaagg aagccagcag acctgcagaa 400

 cttggctccc gggacccacc caccatttat aactttcaac agtgaagtca 450

 aaacggatgt aaataagatt gaggaatttc ttgaagaggt cttatgccct 500

 cccaagtact taaagctttc accaaaacac ccagaatcaa atactgctgg 550

 aatggacatc tttgccaaat tctctgcata tatcaagaat tcaaggccag 600

 aggctaatga agcactggag aggggtctcc tgaaaaccct gcagaaactg 650

 gatgaatatc tgaattctcc tctccctgat gaaattgatg aaaatagtat 700

 ggaggacata aagttttcta cacgtaaatt tctggatggc aatgaaatga 750

 cattagctga ttgcaacctg ctgcccaaac tgcatattgt caaggtggtg 800

 gccaaaaaat atcgcaactt tgatattcca aaagaaatga ctggcatctg 850

 gagataccta actaatgcat acagtaggga cgagttcacc aatacctgtc 900

 ccagtgataa ggaggttgaa atagcatata gtgatgtagc caaaagactc 950

 accaagtaaa atcgcgtttg taaaagagat gtcttcatgt cttcccctaa 1000

 gaatacgctt ttcctaacag gctactcctt cctgtagagc agaaattgta 1050

 ttttgcacga acatgcagtt attgaagatt aggatcaagg atagacaagg 1100

 tatagtagtt atcttaaaat atacactcct aagcagtatt attttaaaat 1150

 cctttaccct ggctacctcc cctacccggg ttcccctctc tttaatttgg 1200

 agacactcca ccacaaactt ttcactttag aggtagcttg ccatctctca 1250

 ggagccctca ccattgtgtc cattcactgt gtatagatgg cagaactttt 1300

 gaggtgcaat gtttaattgt taaaaatagt agccacgact ttatcaggca 1350

 gccccaaact ggtgcataat gcatggtaca agaaatattt atgtattttt 1400

 tggaattttg taatatttag taggagtata tgaaaggatt gctactgtat 1450

 cagaaatatt gtttcaattt agtctatcct ggatatgtac taacgaatat 1500

 taccaccaga gaagagagct ttctacaaaa gtcactacag attttgctat 1550

 attgctttgt agatagattt ttacttttgc ctaaaagcat ttatccttca 1600

 taccaattgt aacatctgac accatgtaga agctaaaagt ttagagggag 1650

 tgagcgtttt ctcaagacct tcctcaagca ttttatcttt agaagagaaa 1700

 ctgatgggca cctgatactc tgtctaaata cgtttgttat atgtgttttg 1750

 ccctgtgcca ttcatttgga actttattgc attctttatt ttaaaaagct 1800

 tgtttttacg taatcataga gcttgctatt tgtacatctg ttgagcaaca 1850

 ctacataact gatttttagt tgacttagct atagcagtac aatgattagt 1900

 aatgtaaaaa ttaacacaga aattaaccta aggaatgaag ggtgggtttg 1950

 tcaaaatatc aagtaaattt ttgtttctaa agtacattta atgtagatga 2000

 cctaaagaat gcgttatcca tcctatataa aagaaagata aaacacaggt 2050

 caccaatttt ctcatttcac cccatttacc ttgtatagag gattgttcat 2100

 tcctttggga ctaagttata gttatggtga gtgtgtattt actgtagttt 2150

 tgcctgatct cactcattgc acttcctgga gttaaatttt ccaacagcca 2200

 tgttgaggaa tagcactctg catgtttttg ttttgttttt cggggttttt 2250

 tttaattgaa gccctaaacc aggaattatt tgtgttctaa caggaggatg 2300

 aacttgctga aaataaaact ttgctatgta tttactcttt tttaaaagac 2350

 aaaagcaaaa ccagactttc tacgtactac tccaaagact gtgattgtga 2400

 ctataataca tttttggtaa tttttttata cctaatttgt ataggaagtg 2450

 ctatttctca taggctgttt cttgaaattt taagtttatt gctttaaaat 2500

 ggcagtgttt ctcccacttt gatatgctaa catttagtaa gcactggctt 2550

 tatgaaagcg gctttttata agtatactgc attttttgag cctatcatta 2600

 attagcttag tatgaaagat aagaaaatct ccatgttgta tccatttggc 2650

 tcaggaagat tctttgcctt acctttctta gaactcttta ttgcttatca 2700

 aaagtttgag tacccgcttg gttttttttt ggtaattaaa tattgtatga 2750

 tttatctggt tcaaggaaga tgcactattc agttatctat tgagaaatta 2800

 ttttgcagtg gttttagtgg gtgaaaatgt cccatctgca ccagtacaca 2850

 ggcaggcatt atcattcttc acctactttt taaatagtgg caacttggga 2900

 ttctttctgg tgattctgaa ccttgcctca tagcttaaag tataaaaaaa 2950

 gattcaagag cagtgaggtt tgttctttcc agtgaatggt ggactgagtg 3000

 gtgcgaggtg gagggctaac aagaggaaag aactacattc ttcagaatac 3050

 agtgatgaaa attcattttg aaactcaaat attttcattt tggatattct 3100

 cctgttttta ttaaaccagt gattacacct ggccatccct ctaaatgttc 3150

 taggaaggca tgtctattgt gattttgatg aagacagaat tatttttctc 3200

 tgtagaaaca cagataccac tttatcaggg aagttagtca aatgaaatgg 3250

 aaattggtaa atggacaaaa gctagctagt aaaaaggacg acccagcaac 3300

 atgctttaac cccattgtat gtttgtggaa agagcatagt ttaacatctt 3350

 gagaaatttg ggacataaag ttttcatggt agacagttca tgcagtatat 3400

 gaattgacat aatggaaata atctgatttt atttttacaa ctaacatcca 3450

 ttccccttca tttaaacacc ttttgtgttt tacttcagtg aggagattgg 3500

 agtctgaatg gatctgtttt ccaagagatt ctgagaaatt tttgtattca 3550

 gcagttggaa agctctctat tctagttgat aaaacttccc ttttttgatg 3600

 tagatgcaga tattctatac agttctgttg tcttttacta ggactgtaaa 3650

 cttttgtgat aaaattcaaa taagatttta tttctttgta attttggctt 3700

 tcacaattta tctttaaatc cttgagcaat ctgtatacaa ttaagagatt 3750

 tctgacattt attcttacac taaatggatc aactctagga tttaggcatg 3800

 ttaacttctg ttgtgttttg aatctctcca gagttgcatg tagatagcat 3850

 ttatttctgt gcccttaaac ccatttagaa aataactaca aagtaaaaat 3900

 gtagaggaaa tagaaatgta ttttttcatg aacattttga tacaaatttc 3950

 atcatttaat gattcaccaa tttcttgcat taatttgaat ttaagcattt 4000

 aattcaaaga gaggggagca tccattattg gtacatgtgg gcttttaaaa 4050

 actccatcct ttataaatag tcaaggtttg ggccacacaa agtatatttt 4100

 tatcatggaa aaatttcaac tcctcaagcc gtaatgttga acagaattgg 4150

 agtattttct ttataatttc ttgaacaggc aaatgaaagc ttattataga 4200

 atgcatgtat tttcttttat ctttggaaca tcagcaccag tatattgctg 4250

 gcagctattg tattaaaaaa taaagtatat tttcactatc aaaaaaaaaa 4300

 aaaaaaaaaa aaaaaaaa 4318

<210> 380
<211> 253
<212> PRT
<213> Homo sapien

<400> 380
 Met Ala Leu Ser Met Pro Leu Asn Gly Leu Lys Glu Glu Asp Lys
   1               5                  10                  15

 Glu Pro Leu Ile Glu Leu Phe Val Lys Ala Gly Ser Asp Gly Glu
                  20                  25                  30

 Ser Ile Gly Asn Cys Pro Phe Ser Gln Arg Leu Phe Met Ile Leu
                  35                  40                  45

 Trp Leu Lys Gly Val Val Phe Ser Val Thr Thr Val Asp Leu Lys
                  50                  55                  60

 Arg Lys Pro Ala Asp Leu Gln Asn Leu Ala Pro Gly Thr His Pro
                  65                  70                  75

 Pro Phe Ile Thr Phe Asn Ser Glu Val Lys Thr Asp Val Asn Lys
                  80                  85                  90

 Ile Glu Glu Phe Leu Glu Glu Val Leu Cys Pro Pro Lys Tyr Leu
                  95                 100                 105

 Lys Leu Ser Pro Lys His Pro Glu Ser Asn Thr Ala Gly Met Asp
                 110                 115                 120

 Ile Phe Ala Lys Phe Ser Ala Tyr Ile Lys Asn Ser Arg Pro Glu
                 125                 130                 135

 Ala Asn Glu Ala Leu Glu Arg Gly Leu Leu Lys Thr Leu Gln Lys
                 140                 145                 150

 Leu Asp Glu Tyr Leu Asn Ser Pro Leu Pro Asp Glu Ile Asp Glu
                 155                 160                 165

 Asn Ser Met Glu Asp Ile Lys Phe Ser Thr Arg Lys Phe Leu Asp
                 170                 175                 180

 Gly Asn Glu Met Thr Leu Ala Asp Cys Asn Leu Leu Pro Lys Leu
                 185                 190                 195

 His Ile Val Lys Val Val Ala Lys Lys Tyr Arg Asn Phe Asp Ile
                 200                 205                 210

 Pro Lys Glu Met Thr Gly Ile Trp Arg Tyr Leu Thr Asn Ala Tyr
                 215                 220                 225

 Ser Arg Asp Glu Phe Thr Asn Thr Cys Pro Ser Asp Lys Glu Val
                 230                 235                 240

 Glu Ile Ala Tyr Ser Asp Val Ala Lys Arg Leu Thr Lys
                 245                 250

<210> 381
<211> 4318
<212> DNA
<213> Homo sapien

<400> 381
 aagcggctcg ggctgcggct ggctcagagt gccgcggggg gcgtggggcg 50

 gtgctgagga gctgaagccg tggccagctc gactccggac agtccagcga 100

 gcagcacggc gggaaccggc agccggagca gtcccggagc agaagcagca 150

 gcagcagcag cagccctcgc cgttcgcgga gcgcagccga gccggccatg 200

 gcgttgtcga tgccgctgaa tgggctgaag gaggaggaca aagagcccct 250

 catcgagctc ttcgtcaagg ctggcagtga tggtgaaagc ataggaaact 300

 gccccttttc ccagaggctc ttcatgattc tttggctcaa aggagttgta 350

 tttagtgtga cgactgttga cctgaaaagg aagccagcag acctgcagaa 400

 cttggctccc gggacccacc caccatttat aactttcaac agtgaagtca 450

 aaacggatgt aaataagatt gaggaatttc ttgaagaggt cttatgccct 500

 cccaagtact taaagctttc accaaaacac ccagaatcaa atactgctgg 550

 aatggacatc tttgccaaat tctctgcata tatcaagaat tcaaggccag 600

 aggctaatga agcactggag aggggtctcc tgaaaaccct gcagaaactg 650

 gatgaatatc tgaattctcc tctccctgat gaaattgatg aaaatagtat 700

 ggaggacata aagttttcta cacgtaaatt tctggatggc aatgaaatga 750

 cattagctga ttgcaacctg ctgcccaaac tgcatattgt caaggtggtg 800

 gccaaaaaat atcgcaactt tgatattcca aaagaaatga ctggcatctg 850

 gagataccta actaatgcat acagtaggga cgagttcacc aatacctgtc 900

 ccagtgataa ggaggttgaa atagcatata gtgatgtagc caaaagactc 950

 accaagtaaa atcgcgtttg taaaagagat gtcttcatgt cttcccctaa 1000

 gaatacgctt ttcctaacag gctactcctt cctgtagagc agaaattgta 1050

 ttttgcacga acatgcagtt attgaagatt aggatcaagg atagacaagg 1100

 tatagtagtt atcttaaaat atacactcct aagcagtatt attttaaaat 1150

 cctttaccct ggctacctcc cctacccggg ttcccctctc tttaatttgg 1200

 agacactcca ccacaaactt ttcactttag aggtagcttg ccatctctca 1250

 ggagccctca ccattgtgtc cattcactgt gtatagatgg cagaactttt 1300

 gaggtgcaat gtttaattgt taaaaatagt agccacgact ttatcaggca 1350

 gccccaaact ggtgcataat gcatggtaca agaaatattt atgtattttt 1400

 tggaattttg taatatttag taggagtata tgaaaggatt gctactgtat 1450

 cagaaatatt gtttcaattt agtctatcct ggatatgtac taacgaatat 1500

 taccaccaga gaagagagct ttctacaaaa gtcactacag attttgctat 1550

 attgctttgt agatagattt ttacttttgc ctaaaagcat ttatccttca 1600

 taccaattgt aacatctgac accatgtaga agctaaaagt ttagagggag 1650

 tgagcgtttt ctcaagacct tcctcaagca ttttatcttt agaagagaaa 1700

 ctgatgggca cctgatactc tgtctaaata cgtttgttat atgtgttttg 1750

 ccctgtgcca ttcatttgga actttattgc attctttatt ttaaaaagct 1800

 tgtttttacg taatcataga gcttgctatt tgtacatctg ttgagcaaca 1850

 ctacataact gatttttagt tgacttagct atagcagtac aatgattagt 1900

 aatgtaaaaa ttaacacaga aattaaccta aggaatgaag ggtgggtttg 1950

 tcaaaatatc aagtaaattt ttgtttctaa agtacattta atgtagatga 2000

 cctaaagaat gcgttatcca tcctatataa aagaaagata aaacacaggt 2050

 caccaatttt ctcatttcac cccatttacc ttgtatagag gattgttcat 2100

 tcctttggga ctaagttata gttatggtga gtgtgtattt actgtagttt 2150

 tgcctgatct cactcattgc acttcctgga gttaaatttt ccaacagcca 2200

 tgttgaggaa tagcactctg catgtttttg ttttgttttt cggggttttt 2250

 tttaattgaa gccctaaacc aggaattatt tgtgttctaa caggaggatg 2300

 aacttgctga aaataaaact ttgctatgta tttactcttt tttaaaagac 2350

 aaaagcaaaa ccagactttc tacgtactac tccaaagact gtgattgtga 2400

 ctataataca tttttggtaa tttttttata cctaatttgt ataggaagtg 2450

 ctatttctca taggctgttt cttgaaattt taagtttatt gctttaaaat 2500

 ggcagtgttt ctcccacttt gatatgctaa catttagtaa gcactggctt 2550

 tatgaaagcg gctttttata agtatactgc attttttgag cctatcatta 2600

 attagcttag tatgaaagat aagaaaatct ccatgttgta tccatttggc 2650

 tcaggaagat tctttgcctt acctttctta gaactcttta ttgcttatca 2700

 aaagtttgag tacccgcttg gttttttttt ggtaattaaa tattgtatga 2750

 tttatctggt tcaaggaaga tgcactattc agttatctat tgagaaatta 2800

 ttttgcagtg gttttagtgg gtgaaaatgt cccatctgca ccagtacaca 2850

 ggcaggcatt atcattcttc acctactttt taaatagtgg caacttggga 2900

 ttctttctgg tgattctgaa ccttgcctca tagcttaaag tataaaaaaa 2950

 gattcaagag cagtgaggtt tgttctttcc agtgaatggt ggactgagtg 3000

 gtgcgaggtg gagggctaac aagaggaaag aactacattc ttcagaatac 3050

 agtgatgaaa attcattttg aaactcaaat attttcattt tggatattct 3100

 cctgttttta ttaaaccagt gattacacct ggccatccct ctaaatgttc 3150

 taggaaggca tgtctattgt gattttgatg aagacagaat tatttttctc 3200

 tgtagaaaca cagataccac tttatcaggg aagttagtca aatgaaatgg 3250

 aaattggtaa atggacaaaa gctagctagt aaaaaggacg acccagcaac 3300

 atgctttaac cccattgtat gtttgtggaa agagcatagt ttaacatctt 3350

 gagaaatttg ggacataaag ttttcatggt agacagttca tgcagtatat 3400

 gaattgacat aatggaaata atctgatttt atttttacaa ctaacatcca 3450

 ttccccttca tttaaacacc ttttgtgttt tacttcagtg aggagattgg 3500

 agtctgaatg gatctgtttt ccaagagatt ctgagaaatt tttgtattca 3550

 gcagttggaa agctctctat tctagttgat aaaacttccc ttttttgatg 3600

 tagatgcaga tattctatac agttctgttg tcttttacta ggactgtaaa 3650

 cttttgtgat aaaattcaaa taagatttta tttctttgta attttggctt 3700

 tcacaattta tctttaaatc cttgagcaat ctgtatacaa ttaagagatt 3750

 tctgacattt attcttacac taaatggatc aactctagga tttaggcatg 3800

 ttaacttctg ttgtgttttg aatctctcca gagttgcatg tagatagcat 3850

 ttatttctgt gcccttaaac ccatttagaa aataactaca aagtaaaaat 3900

 gtagaggaaa tagaaatgta ttttttcatg aacattttga tacaaatttc 3950

 atcatttaat gattcaccaa tttcttgcat taatttgaat ttaagcattt 4000

 aattcaaaga gaggggagca tccattattg gtacatgtgg gcttttaaaa 4050

 actccatcct ttataaatag tcaaggtttg ggccacacaa agtatatttt 4100

 tatcatggaa aaatttcaac tcctcaagcc gtaatgttga acagaattgg 4150

 agtattttct ttataatttc ttgaacaggc aaatgaaagc ttattataga 4200

 atgcatgtat tttcttttat ctttggaaca tcagcaccag tatattgctg 4250

 gcagctattg tattaaaaaa taaagtatat tttcactatc aaaaaaaaaa 4300

 aaaaaaaaaa aaaaaaaa 4318

<210> 382
<211> 253
<212> PRT
<213> Homo sapien

<400> 382
 Met Ala Leu Ser Met Pro Leu Asn Gly Leu Lys Glu Glu Asp Lys
   1               5                  10                  15

 Glu Pro Leu Ile Glu Leu Phe Val Lys Ala Gly Ser Asp Gly Glu
                  20                  25                  30

 Ser Ile Gly Asn Cys Pro Phe Ser Gln Arg Leu Phe Met Ile Leu
                  35                  40                  45

 Trp Leu Lys Gly Val Val Phe Ser Val Thr Thr Val Asp Leu Lys
                  50                  55                  60

 Arg Lys Pro Ala Asp Leu Gln Asn Leu Ala Pro Gly Thr His Pro
                  65                  70                  75

 Pro Phe Ile Thr Phe Asn Ser Glu Val Lys Thr Asp Val Asn Lys
                  80                  85                  90

 Ile Glu Glu Phe Leu Glu Glu Val Leu Cys Pro Pro Lys Tyr Leu
                  95                 100                 105

 Lys Leu Ser Pro Lys His Pro Glu Ser Asn Thr Ala Gly Met Asp
                 110                 115                 120

 Ile Phe Ala Lys Phe Ser Ala Tyr Ile Lys Asn Ser Arg Pro Glu
                 125                 130                 135

 Ala Asn Glu Ala Leu Glu Arg Gly Leu Leu Lys Thr Leu Gln Lys
                 140                 145                 150

 Leu Asp Glu Tyr Leu Asn Ser Pro Leu Pro Asp Glu Ile Asp Glu
                 155                 160                 165

 Asn Ser Met Glu Asp Ile Lys Phe Ser Thr Arg Lys Phe Leu Asp
                 170                 175                 180

 Gly Asn Glu Met Thr Leu Ala Asp Cys Asn Leu Leu Pro Lys Leu
                 185                 190                 195

 His Ile Val Lys Val Val Ala Lys Lys Tyr Arg Asn Phe Asp Ile
                 200                 205                 210

 Pro Lys Glu Met Thr Gly Ile Trp Arg Tyr Leu Thr Asn Ala Tyr
                 215                 220                 225

 Ser Arg Asp Glu Phe Thr Asn Thr Cys Pro Ser Asp Lys Glu Val
                 230                 235                 240

 Glu Ile Ala Tyr Ser Asp Val Ala Lys Arg Leu Thr Lys
                 245                 250

<210> 383
<211> 640
<212> DNA
<213> Homo sapien

<400> 383
 attctgagcc gagcccggtg ccaagcgcag ctagctcagc aggcggcagc 50

 ggcggcctga gcttcagggc agccagctcc tcccggtctc gccttcctcg 100

 cggtcagcat gaaagccttc agtcccgtga ggtccgttag gaaaaacagc 150

 ctgtcggacc acagcctggg catctcccgg agcaaaaccc ctgtggacga 200

 cccgatgagc ctgctataca acatgaacga ctgctactcc aagctcaagg 250

 agctggtgcc cagcatcccc cagaacaaga aggtgagcaa gatggaaatc 300

 ctgcagcacc tcatcgacta catcttggac ctgcagatcg ccctggactc 350

 gcatcccact attgtcagcc tgcatcacca gagacccggg cagaaccagc 400

 gctccaggac gccgctgacc accctcaaca cggatatcag catcctgtcc 450

 ttgcaggctt ctgaattccc ttctgagtta atgtcaaatg acagcaaagc 500

 actgtgtggc tgaataagcg gtgttcatga tttcttttat tctttgcaca 550

 acaacaacaa caacaaattc acggaatctt ttaagtgctg aacttatttt 600

 tcaaccattt cacaaggagg acaagttgaa tggacctttt 640

<210> 384
<211> 134
<212> PRT
<213> Homo sapien

<400> 384
 Met Lys Ala Phe Ser Pro Val Arg Ser Val Arg Lys Asn Ser Leu
   1               5                  10                  15

 Ser Asp His Ser Leu Gly Ile Ser Arg Ser Lys Thr Pro Val Asp
                  20                  25                  30

 Asp Pro Met Ser Leu Leu Tyr Asn Met Asn Asp Cys Tyr Ser Lys
                  35                  40                  45

 Leu Lys Glu Leu Val Pro Ser Ile Pro Gln Asn Lys Lys Val Ser
                  50                  55                  60

 Lys Met Glu Ile Leu Gln His Leu Ile Asp Tyr Ile Leu Asp Leu
                  65                  70                  75

 Gln Ile Ala Leu Asp Ser His Pro Thr Ile Val Ser Leu His His
                  80                  85                  90

 Gln Arg Pro Gly Gln Asn Gln Arg Ser Arg Thr Pro Leu Thr Thr
                  95                 100                 105

 Leu Asn Thr Asp Ile Ser Ile Leu Ser Leu Gln Ala Ser Glu Phe
                 110                 115                 120

 Pro Ser Glu Leu Met Ser Asn Asp Ser Lys Ala Leu Cys Gly
                 125                 130

<210> 385
<211> 1049
<212> DNA
<213> Homo sapien

<400> 385
 gcccggtgcc aagcgcagct agctcagcag gcggcagcgg cggcctgagc 50

 ttcagggcag ccagctcctc ccggtctcgc cttcctcgcg gtcagcatga 100

 aagccttcag tcccgtgagg tccgttagga aaaacagcct gtcggaccac 150

 agcctgggca tctcccggag caaaacccct gtggacgacc cgatgagcct 200

 gctatacaac atgaacgact gctactccaa gctcaaggag ctggtgccca 250

 gcatccccca gaacaagaag gtgagcaaga tggaaatcct gcagcacgtc 300

 atcgactaca tcttggacct gcagatcgcc ctggactcgc atcccactat 350

 tgtcagcctg catcaccaga gacccgggca gaaccaggcg tccaggacgc 400

 cgctgaccac cctcaacacg gatatcagca tcctgtcctt gcaggcttct 450

 gaattccctt ctgagttaat gtcaaatgac agcaaagcac tgtgtggctg 500

 aataagcggt gttcatgatt tcttttattc tttgcacaac aacaacaaca 550

 acaaattcac ggaatctttt aagtgctgaa cttatttttc aaccatttca 600

 caaggaggac aagttgaatg gaccttttta aaaagaaaaa aaaaatgaag 650

 gaaaactaag aatgatcatc ttcccagggt tcttacttga ctgtaattcg 700

 ttatttatga aaaaaccttt taaatgccct ttctgcagtt ggaaggtttt 750

 ctttatatac tattcccacc atggggagcg aaaacgttaa aatcacaagg 800

 aattgcccaa tctaagcaga ctttgccttt tttcaaaggt ggagcgtgat 850

 accagaagga tccagtattc agtcacttaa atgaagtctt ttggtcagaa 900

 attacctttt tcacacaagc ctactgaatg ctgtgtatat atttatatat 950

 aaatatatct atttgagtga aaccttgtga acctttaatt agagtcttct 1000

 tgtatagtgg cagagatgtc tattctgcat caaagtgtaa tgatgtact 1049

<210> 386
<211> 134
<212> PRT
<213> Homo sapien

<400> 386
 Met Lys Ala Phe Ser Pro Val Arg Ser Val Arg Lys Asn Ser Leu
   1               5                  10                  15

 Ser Asp His Ser Leu Gly Ile Ser Arg Ser Lys Thr Pro Val Asp
                  20                  25                  30

 Asp Pro Met Ser Leu Leu Tyr Asn Met Asn Asp Cys Tyr Ser Lys
                  35                  40                  45

 Leu Lys Glu Leu Val Pro Ser Ile Pro Gln Asn Lys Lys Val Ser
                  50                  55                  60

 Lys Met Glu Ile Leu Gln His Val Ile Asp Tyr Ile Leu Asp Leu
                  65                  70                  75

 Gln Ile Ala Leu Asp Ser His Pro Thr Ile Val Ser Leu His His
                  80                  85                  90

 Gln Arg Pro Gly Gln Asn Gln Ala Ser Arg Thr Pro Leu Thr Thr
                  95                 100                 105

 Leu Asn Thr Asp Ile Ser Ile Leu Ser Leu Gln Ala Ser Glu Phe
                 110                 115                 120

 Pro Ser Glu Leu Met Ser Asn Asp Ser Lys Ala Leu Cys Gly
                 125                 130

<210> 387
<211> 2261
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2261
<223> Unknown base

<400> 387
 gaattccgca gccgctgccg ccaggactgg gccttaggga ggaggaggcg 50

 agaagatggc ggacgacccc agtgctgccg acaggaacgt ggagatctgg 100

 aagatcaaga agctcattaa gagcttggag gcggcccgcg gcaatggcac 150

 cagcatgata tcattgatca ttcctcccaa agaccagatt tcacgagtgg 200

 caaaaatgtt agcggatgag tttggaactg catctaacat taagtctcga 250

 gtaaaccgcc tttcagtcct gggagccatt acatctgtac aacaaagact 300

 caaactttat aacaaagtac ctccaaatgg tctggaagta tactgtggaa 350

 caattgtaac agaagaagga aaggaaaaga aagtcaacat tgactttgaa 400

 cctttcaaac caattaatac gtcattgtat ttgtgtgaca acaaattcca 450

 tacagaggct cttacagcac tactttcaga tgatagcaag tttggattca 500

 ttgtaataga tggtagtggt gcactttttg gcacactcca aggaaacaca 550

 agagaagtcc tgcacaaatt cactgtggat ctcccaaaga aacacggtag 600

 aggaggtcag tcagccttgc gttttgcccg tttaagaatg gaaaagcgac 650

 ataactatgt tcggaaagta gcagagactg ctgtgcagct gtttatttct 700

 ggggacaaag tgaatgtggc tggtctagtt ttagctggat ccgctgactt 750

 taaaactgaa ctaagtcaat ctgatatgtt tgatcagagg ttacaatcaa 800

 aagttttaaa attagttgat atatcctatg gtggtgaaaa tggattcaac 850

 caagctattg agttatctac tgaagtcctc tccaacgtga aattcattca 900

 agagaagaaa ttaataggac gatactttga tgaaatcagc caggactcac 950

 tggcaagtac tgttttggcg ttgaagatac acataggctt tggaatggga 1000

 gctgtagaaa attctaatag tcatatgaaa tctggatata atgagatatg 1050

 ttcttcattg ccaaggcaca gaagaagaaa tctctatcta actccagagc 1100

 aagaaaagga taaatctcat ttcacagaca aagagaccgg acaggaacat 1150

 gagcttatcg agagcatgcc cctgttggaa tggtttgcta acaactataa 1200

 aaatttggag ctacgttgga aattgtcaca gataaatcac aagaagggtc 1250

 tcagtttgat gaaaggattt ggtggaattg gaggtatctt gcggtaccag 1300

 agtagatttc cagggaatgg aataccaagg aggagacgat gaattttttg 1350

 accttgatga ctactaggta gtcgacatgg gtccggcaaa acgtgcctca 1400

 ccctccagca tccaacccaa ggagcatacc catggtggaa tccaaacaga 1450

 tccctgtcct tacaattgga acatttccag aacttaatcc atgagcattg 1500

 gatattgaaa gaaaccgaaa caaaaccaga cccagcccta cactttggtt 1550

 tgtcatggtg cagcgcagca gcctaactaa ctaatgttcc ttcaaaagcc 1600

 actttggacg taatttaaaa aagaatccca gtttttactt ttactggatg 1650

 gtgaaattgg ttgctcttgt attttatgaa aaaaaatgat ttttttaacc 1700

 ttcatacata gaagcaaaaa tactttaact gctgtaaacc ttcaaaagtt 1750

 aatagaagtg agatcatact ggtttgtttc ttatttttga ttggagaaaa 1800

 attaaattgc tgcatttcgc ctaggtgacc atttacatgg attctcagtt 1850

 agactgcgta agaagaaata tatgtggtga aatgttggaa ccatttctct 1900

 cttggtctct gtttaatgtt gaagggtgag ctattaggag gcactttcaa 1950

 cttcactccc tcacgctacc ccgtccccct ccagactggc agtttcaagg 2000

 atgcaaattg cattgcaaaa tcaaactgac tcatgaagca tttgggccag 2050

 tgcactgttt acttccatct gtttgcagac acatttgtgc ccggcgtttg 2100

 ggagcccttt gtatcaatgt tctgacaagg gtccctataa ccttaaccta 2150

 ctcgaaaccg gtttgggatg gatatgatgg ggcttctgtg ctattgctgg 2200

 gattgggaga aataaaacat gcaatttaag tggaagcgaa gaaatttaaa 2250

 aaaaaaaaaa n 2261

<210> 388
<211> 428
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2261
<223> Unknown amino acid

<400> 388
 Met Ala Asp Asp Pro Ser Ala Ala Asp Arg Asn Val Glu Ile Trp
   1               5                  10                  15

 Lys Ile Lys Lys Leu Ile Lys Ser Leu Glu Ala Ala Arg Gly Asn
                  20                  25                  30

 Gly Thr Ser Met Ile Ser Leu Ile Ile Pro Pro Lys Asp Gln Ile
                  35                  40                  45

 Ser Arg Val Ala Lys Met Leu Ala Asp Glu Phe Gly Thr Ala Ser
                  50                  55                  60

 Asn Ile Lys Ser Arg Val Asn Arg Leu Ser Val Leu Gly Ala Ile
                  65                  70                  75

 Thr Ser Val Gln Gln Arg Leu Lys Leu Tyr Asn Lys Val Pro Pro
                  80                  85                  90

 Asn Gly Leu Glu Val Tyr Cys Gly Thr Ile Val Thr Glu Glu Gly
                  95                 100                 105

 Lys Glu Lys Lys Val Asn Ile Asp Phe Glu Pro Phe Lys Pro Ile
                 110                 115                 120

 Asn Thr Ser Leu Tyr Leu Cys Asp Asn Lys Phe His Thr Glu Ala
                 125                 130                 135

 Leu Thr Ala Leu Leu Ser Asp Asp Ser Lys Phe Gly Phe Ile Val
                 140                 145                 150

 Ile Asp Gly Ser Gly Ala Leu Phe Gly Thr Leu Gln Gly Asn Thr
                 155                 160                 165

 Arg Glu Val Leu His Lys Phe Thr Val Asp Leu Pro Lys Lys His
                 170                 175                 180

 Gly Arg Gly Gly Gln Ser Ala Leu Arg Phe Ala Arg Leu Arg Met
                 185                 190                 195

 Glu Lys Arg His Asn Tyr Val Arg Lys Val Ala Glu Thr Ala Val
                 200                 205                 210

 Gln Leu Phe Ile Ser Gly Asp Lys Val Asn Val Ala Gly Leu Val
                 215                 220                 225

 Leu Ala Gly Ser Ala Asp Phe Lys Thr Glu Leu Ser Gln Ser Asp
                 230                 235                 240

 Met Phe Asp Gln Arg Leu Gln Ser Lys Val Leu Lys Leu Val Asp
                 245                 250                 255

 Ile Ser Tyr Gly Gly Glu Asn Gly Phe Asn Gln Ala Ile Glu Leu
                 260                 265                 270

 Ser Thr Glu Val Leu Ser Asn Val Lys Phe Ile Gln Glu Lys Lys
                 275                 280                 285

 Leu Ile Gly Arg Tyr Phe Asp Glu Ile Ser Gln Asp Ser Leu Ala
                 290                 295                 300

 Ser Thr Val Leu Ala Leu Lys Ile His Ile Gly Phe Gly Met Gly
                 305                 310                 315

 Ala Val Glu Asn Ser Asn Ser His Met Lys Ser Gly Tyr Asn Glu
                 320                 325                 330

 Ile Cys Ser Ser Leu Pro Arg His Arg Arg Arg Asn Leu Tyr Leu
                 335                 340                 345

 Thr Pro Glu Gln Glu Lys Asp Lys Ser His Phe Thr Asp Lys Glu
                 350                 355                 360

 Thr Gly Gln Glu His Glu Leu Ile Glu Ser Met Pro Leu Leu Glu
                 365                 370                 375

 Trp Phe Ala Asn Asn Tyr Lys Asn Leu Glu Leu Arg Trp Lys Leu
                 380                 385                 390

 Ser Gln Ile Asn His Lys Lys Gly Leu Ser Leu Met Lys Gly Phe
                 395                 400                 405

 Gly Gly Ile Gly Gly Ile Leu Arg Tyr Gln Ser Arg Phe Pro Gly
                 410                 415                 420

 Asn Gly Ile Pro Arg Arg Arg Arg
                 425

<210> 389
<211> 3653
<212> DNA
<213> Homo sapien

<400> 389
 attgcaacac atgcagctgc ctggagagag ggagccggtg tcctacgtca 50

 gagccgccgc cgccgcgagc cgccgccggg gaggagcagc cgctgccgcc 100

 caggactggg cccttaggga ggaggaggcg agaagatggc ggacgacccc 150

 agtgctgccg acaggaacgt ggagatctgg aagatcaaga agctcattaa 200

 gagcttggag gcggcccgcg gcaatggcac cagcatgata tcattgatca 250

 ttcctcccaa agaccagatt tcacgagtgg caaaaatgtt agcggatgag 300

 tttggaactg catctaacat taagtcacga gtaaaccgcc tttcagtcct 350

 gggagccatt acatctgtac aacaaagact caaactttat aacaaagtac 400

 ctccaaatgg tctggttgta tactgtggaa caattgtaac agaagaagga 450

 aaggaaaaga aagtcaacat tgactttgaa cctttcaaac caattaatac 500

 gtcattgtat ttgtgtgaca acaaattcca tacagaggct cttacagcac 550

 tactttcaga tgatagcaag tttggattca ttgtaataga tggtagtggt 600

 gcactttttg gcacactcca aggaaacaca agagaagtcc tgcacaaatt 650

 cactgtggat ctcccaaaga aacacggtag aggaggtcag tcagccttgc 700

 gttttgcccg tttaagaatg gaaaagcgac ataactatgt tcggaaagta 750

 gcagagactg ctgtgcagct gtttatttct ggggacaaag tgaatgtggc 800

 tggtctagtt ttagctggat ccgctgactt taaaactgaa ctaagtcaat 850

 ctgatatgtt tgatcagagg ttacaatcaa aagttttaaa attagttgat 900

 atatcctatg gtggtgaaaa tggattcaac caagctattg agttatctac 950

 tgaagtcctc tccaacgtga aattcattca agagaagaaa ttaataggac 1000

 gatactttga tgaaatcagc caggacacgg gcaagtactg ttttggcgtt 1050

 gaagatacac taaaggcttt ggaaatggga gctgtagaaa ttctaatagt 1100

 ctatgaaaat ctggatataa tgagatatgt tcttcattgc caaggcacag 1150

 aagaggagaa aattctctat ctaactccag agcaagaaaa ggataaatct 1200

 catttcacag acaaagagac cggacaggaa catgagctta tcgagagcat 1250

 gcccctgttg gaatggtttg ctaacaacta taaaaaattt ggagctacgt 1300

 tggaaattgt cacagataaa tcacaagaag ggtctcagtt tgtgaaagga 1350

 tttggtggaa ttggaggtat cttgcggtac cgagtagatt tccagggaat 1400

 ggaataccaa ggaggagacg atgaattttt tgaccttgat gactactagg 1450

 tagtcgacat gggtccggca aaacgtgcct caccctccag catccaaccc 1500

 aaggagcata cccatggtgg aatccaaaca gatccctgcc ttacaattgg 1550

 aacatttcca gaacttaatc catgagcatt ggatattgaa aagaaaaccg 1600

 aaacaaaacc agacccagcc ctacactttg gtttgtcatg gtgtcagcgc 1650

 agcagcctac aactaagttc ctaaacgcca ctttggacta atttaaaaaa 1700

 gaatcccagt ttttactttt actggatggt gaaattggtt gctcttgtat 1750

 tttatgaaaa aaaatgattt ttttaacctt catacataga agcaaaaata 1800

 ctttaactgc tgtaaacctt caaaagttaa tagaagtgag atcatactgg 1850

 tttgtttctt attttgattg gagaaaaatt aaattgctgc atttcgcagt 1900

 gacccattta catggcattc tcagcttaga ctgcgtaaga agaaatatat 1950

 gtggtgaaat gttggaacca tttctctctt ggtctctgtt taatgttgaa 2000

 agggtgagct aataggaggc actttcaact tcactccctc acgctacccc 2050

 gtccccctcc agactggcag tttcaaggat gcaaattgca ttgcaaaatc 2100

 aaactgactc atgaagcatt tgggccagtg cactgtttac ttccatctgt 2150

 ttgcagacac atttgtgccc ggcgtttggg agccctttgt atcaatgttc 2200

 tgacaagggt ccctataacc ttaacctact cgaaaccggt ttgggatgga 2250

 tatgatgggg cttctgtgct attgctggga ttgggagaaa taaaacatgc 2300

 aatttaagtg gaagcgaaga aatttaaaga ggattttatt ttgcttgggt 2350

 caatccttgt taaaagggag gtggatgtgt ttccttgtgt tggatggcat 2400

 gagattatgt gaatgttttg atttattaaa atgaactgca aggtttttca 2450

 caggaacgac agacatgtat gactgcatgt aattataaac tcctgacctc 2500

 ctggtggggt tggagcatct gtttcaaatg tgggacttac aagcacttct 2550

 cacatgagaa attaggggcg ggtgggaagg gatgggacac agcttctggc 2600

 accatggatt taagaccatg ttggatccaa aagttggcct gaaaccctga 2650

 agctgatgct tcacagctgg gctgtaagtc agacttgaac ccagctgata 2700

 tgcaaggtca tggcgtgcca gggtggtgac agttgaacaa agtgtatagt 2750

 acgtgcccag tggtagcgat ggaaaaaagt ataccaaatg gactttgaag 2800

 gaccaaaggt tttaaaagtc aattggtatc acctccacac tgactagggt 2850

 agtggggtgc atttggtttt caaattgggt acttttaaca ctttagtgcc 2900

 tgactgctgt tctttactga cttgattcag tcactcgtag ctttattggt 2950

 ctgaaccagc tccttgttcc caggttacag acctgcctat cgttccaata 3000

 atcctgtttc acttgaatga agggagtatg tcttaaatgt aaagtttctg 3050

 gttctcacac tgtactctga ggtccaaata ctgtctgtca atgtgtaacc 3100

 tgatgtctca accccctgtg agaagagtcc attatttggt gttcaccaac 3150

 gtgggagact tcaccggaac aggctttttt gctttgggct ctgctatttg 3200

 tttgcagaac acccaagagc gagcaaacac gctctcttca cagcagtacc 3250

 ttagggtttt gccattgtaa atgggtctga tgtgatatga caagaccaga 3300

 gaaattggat gtaaatttac atttttgaat atgcttgttg tttcacatga 3350

 tacatttagg gtatgcagct ccttttgtag tttttatttt tactatttaa 3400

 gtttggaaat gatgccaaat ttttgtattt ctttaatcaa tgtgttctct 3450

 tcggtgatat atattgcatt atatattgat gtgtgtatca atatatattg 3500

 atatgtatta cacttacaca tacaaacaca tataagaggg ggtgaaaacc 3550

 gtagcctttg cattctctat agcctctgca gagagatact aagcagcaaa 3600

 atcttggtgt tgtgatgtac agaaatggag aagagtatta aaccatattt 3650

 aag 3653

<210> 390
<211> 437
<212> PRT
<213> Homo sapien

<400> 390
 Met Ala Asp Asp Pro Ser Ala Ala Asp Arg Asn Val Glu Ile Trp
   1               5                  10                  15

 Lys Ile Lys Lys Leu Ile Lys Ser Leu Glu Ala Ala Arg Gly Asn
                  20                  25                  30

 Gly Thr Ser Met Ile Ser Leu Ile Ile Pro Pro Lys Asp Gln Ile
                  35                  40                  45

 Ser Arg Val Ala Lys Met Leu Ala Asp Glu Phe Gly Thr Ala Ser
                  50                  55                  60

 Asn Ile Lys Ser Arg Val Asn Arg Leu Ser Val Leu Gly Ala Ile
                  65                  70                  75

 Thr Ser Val Gln Gln Arg Leu Lys Leu Tyr Asn Lys Val Pro Pro
                  80                  85                  90

 Asn Gly Leu Val Val Tyr Cys Gly Thr Ile Val Thr Glu Glu Gly
                  95                 100                 105

 Lys Glu Lys Lys Val Asn Ile Asp Phe Glu Pro Phe Lys Pro Ile
                 110                 115                 120

 Asn Thr Ser Leu Tyr Leu Cys Asp Asn Lys Phe His Thr Glu Ala
                 125                 130                 135

 Leu Thr Ala Leu Leu Ser Asp Asp Ser Lys Phe Gly Phe Ile Val
                 140                 145                 150

 Ile Asp Gly Ser Gly Ala Leu Phe Gly Thr Leu Gln Gly Asn Thr
                 155                 160                 165

 Arg Glu Val Leu His Lys Phe Thr Val Asp Leu Pro Lys Lys His
                 170                 175                 180

 Gly Arg Gly Gly Gln Ser Ala Leu Arg Phe Ala Arg Leu Arg Met
                 185                 190                 195

 Glu Lys Arg His Asn Tyr Val Arg Lys Val Ala Glu Thr Ala Val
                 200                 205                 210

 Gln Leu Phe Ile Ser Gly Asp Lys Val Asn Val Ala Gly Leu Val
                 215                 220                 225

 Leu Ala Gly Ser Ala Asp Phe Lys Thr Glu Leu Ser Gln Ser Asp
                 230                 235                 240

 Met Phe Asp Gln Arg Leu Gln Ser Lys Val Leu Lys Leu Val Asp
                 245                 250                 255

 Ile Ser Tyr Gly Gly Glu Asn Gly Phe Asn Gln Ala Ile Glu Leu
                 260                 265                 270

 Ser Thr Glu Val Leu Ser Asn Val Lys Phe Ile Gln Glu Lys Lys
                 275                 280                 285

 Leu Ile Gly Arg Tyr Phe Asp Glu Ile Ser Gln Asp Thr Gly Lys
                 290                 295                 300

 Tyr Cys Phe Gly Val Glu Asp Thr Leu Lys Ala Leu Glu Met Gly
                 305                 310                 315

 Ala Val Glu Ile Leu Ile Val Tyr Glu Asn Leu Asp Ile Met Arg
                 320                 325                 330

 Tyr Val Leu His Cys Gln Gly Thr Glu Glu Glu Lys Ile Leu Tyr
                 335                 340                 345

 Leu Thr Pro Glu Gln Glu Lys Asp Lys Ser His Phe Thr Asp Lys
                 350                 355                 360

 Glu Thr Gly Gln Glu His Glu Leu Ile Glu Ser Met Pro Leu Leu
                 365                 370                 375

 Glu Trp Phe Ala Asn Asn Tyr Lys Lys Phe Gly Ala Thr Leu Glu
                 380                 385                 390

 Ile Val Thr Asp Lys Ser Gln Glu Gly Ser Gln Phe Val Lys Gly
                 395                 400                 405

 Phe Gly Gly Ile Gly Gly Ile Leu Arg Tyr Arg Val Asp Phe Gln
                 410                 415                 420

 Gly Met Glu Tyr Gln Gly Gly Asp Asp Glu Phe Phe Asp Leu Asp
                 425                 430                 435

 Asp Tyr


<210> 391
<211> 732
<212> DNA
<213> Homo sapien

<400> 391
 tgctgcgaac cacgtgggtc ccgggcgcgt ttcgggtgct ggcggctgca 50

 gccggagttc aaacctaagc agctggaagg aaccatggcc aactgtgagc 100

 gtaccttcat tgcgatcaaa ccagatgggg tccagcgggg tcttgtggga 150

 gagattatca agcgttttga gcagaaagga ttccgccttg ttggtctgaa 200

 attcatgcaa gcttccgaag atcttctcaa ggaacactac gttgacctga 250

 aggaccgtcc attctttgcc ggcctggtga aatacatgca ctcagggccg 300

 gtagttgcca tggtctggga ggggctgaat gtggtgaaga cgggccgagt 350

 catgctcggg gagaccaacc ctgcagactc caagcctggg accatccgtg 400

 gagacttctg catacaagtt ggcaggaaca ttatacatgg cagtgattct 450

 gtggagagtg cagagaagga gatcggcttg tggtttcacc ctgaggaact 500

 ggtagattac acgagctgtg ctcagaactg gatctatgaa tgacaggagg 550

 gcagaccaca ttgcttttca catccatttc ccctccttcc catgggcaga 600

 ggaccaggct gtaggaaatc tagttattta caggaacttc atcataattt 650

 ggagggaagc tcttggagct gtgagttctc cctgtacagt gttaccatcc 700

 ccgaccatct gattaaaatg cttcctccca gc 732

<210> 392
<211> 152
<212> PRT
<213> Homo sapien

<400> 392
 Met Ala Asn Cys Glu Arg Thr Phe Ile Ala Ile Lys Pro Asp Gly
   1               5                  10                  15

 Val Gln Arg Gly Leu Val Gly Glu Ile Ile Lys Arg Phe Glu Gln
                  20                  25                  30

 Lys Gly Phe Arg Leu Val Gly Leu Lys Phe Met Gln Ala Ser Glu
                  35                  40                  45

 Asp Leu Leu Lys Glu His Tyr Val Asp Leu Lys Asp Arg Pro Phe
                  50                  55                  60

 Phe Ala Gly Leu Val Lys Tyr Met His Ser Gly Pro Val Val Ala
                  65                  70                  75

 Met Val Trp Glu Gly Leu Asn Val Val Lys Thr Gly Arg Val Met
                  80                  85                  90

 Leu Gly Glu Thr Asn Pro Ala Asp Ser Lys Pro Gly Thr Ile Arg
                  95                 100                 105

 Gly Asp Phe Cys Ile Gln Val Gly Arg Asn Ile Ile His Gly Ser
                 110                 115                 120

 Asp Ser Val Glu Ser Ala Glu Lys Glu Ile Gly Leu Trp Phe His
                 125                 130                 135

 Pro Glu Glu Leu Val Asp Tyr Thr Ser Cys Ala Gln Asn Trp Ile
                 140                 145                 150

 Tyr Glu


<210> 393
<211> 5224
<212> DNA
<213> Homo sapien

<400> 393
 ggctcataga gctgaacagt tgcaggatgc ggaggaggaa aaagatgatt 50

 caaatgaaga agaaaacaaa gacagccttg tagatgatga agaagagaaa 100

 gaagatcttg gcgatgagga tgaagcagag gaagaagagg aggaggacaa 150

 cttggctgct ggtgtggatg aggagagaag tgaggccaat gatcaggggc 200

 ccccaggaga ggacggtgtg acccgggagg aagtagagcc tgaggaggct 250

 gaagaaggca tctctgagca accctgccca gctgacacag aggtggtgga 300

 agactccttg aggcagcgta aaagtcagca tgctgacaag ggactgtaga 350

 tttaatgatg cgttttcaag aatacacacc aaaacaatat gtcagcttcc 400

 ctttggcctg cagtttgtac caaatcctta atttttcctg aatgagcaag 450

 cttctcttaa aagatgctct ctagtcattt ggtctcatgg cagtaagcct 500

 catgtatact aaggagagtc ttccaggtgt gacaatcagg atatagaaaa 550

 acaaacgtag tgttgggatc tgtttggaga ctgggatggg aacaagttca 600

 tttacttagg ggtcagagag tctcgaccag aggaggccat tcccagtcct 650

 aatcagcacc ttccagagac aaggctgcag gccctgtgaa atgaaagcca 700

 agcaggagcc ttggctcctg agcatcccca aagtgtaacg tagaagcctt 750

 gcatcctttt cttgtgtaaa gtatttattt ttgtcaaatt gcaggaaaca 800

 tcaggcacca cagtgcatga aaaatctttc acagctagaa attgaaaggg 850

 ccttgggtat agagagcagc tcagaagtca tcccagccct ctgaatctcc 900

 tgtgctatgt tttatttctt acctttaatt tttccagcat ttccaccatg 950

 ggcattcagg ctctccacac tcttcactat tatctcttgg tcagaggact 1000

 ccaataacag ccaggtttac atgaactgtg tttgttcatt ctgacctaag 1050

 gggtttagat aatcagtaac cataacccct gaagctgtga ctgccaaaca 1100

 tctcaaatga aatgttgtgg ccatcagaga ctcaaaagga agtaaggatt 1150

 ttacaagaca gattaaaaaa aaatggtttt gtccaaaata tagttgttgt 1200

 tgattttttt ttaagttttc taagcaatat ttttcaagcc agaagtcctc 1250

 taagtcttgc cagtacaagg tagtcttgtg aagaaaagtt gaatactgtt 1300

 ttgttttcat ctcaaggggt tccctgggtc ttgaactact ttaataataa 1350

 ctaaaaaacc acttctgatt ttccttcagt gatgtgcttt tggtgaaaga 1400

 attaatgaac tccagtacct gaaagtgaaa gatttgattt tgtttccatc 1450

 ttctgtaatc ttccaaagaa ttatatcttt gtaaatctct caatactcaa 1500

 cctactgtaa gtacccaggg aggctaattt ccttaaaaaa aaaaaatcta 1550

 tccatctact tctctcttac ctgatttatg tgttagaata aattcatgaa 1600

 attcgattcc aagcatacga aagatgccta aagttgattc tatgctcctt 1650

 agatccagac agaataatga gtacaggttt atgaaattct aaaagtttct 1700

 gtcgtcttta aaaaggaacg tgcagtatat ttctatctgg ctgtttagat 1750

 aaccctttcc ttgtattaat tgtgagcacg gagctcactg gtgggggagg 1800

 ttctgaaact ctctgccctc ctgtggttga atgaagatgt tgcaagactt 1850

 gcacaaagga ggttattctt ctgacagcat caacttttag agatggttct 1900

 ttttcatctt tccaattcag ttacttgaca gtctccttcc ccagtatgct 1950

 gaagtttgtt aagagtcacc agtaattgtg cttttcagac agtagtgcag 2000

 cttcaaaatc gaggccatca ctgggctgat gggctgggag aaccttgcca 2050

 tgtgcctgcc tgtttcctgc ccccttagtc actgcccatt tcctgccccc 2100

 ttggtcgctg acacaccttc acccaaagtg ccatggttct gatggtggca 2150

 gttccatctc cctgacatca ggaagctttt ctcgatcaga gcagagcggg 2200

 gcctgcctgc cctcgtgtca ctggatttct ttctcttata atcagctgaa 2250

 acagagttct caaagaacag taaactcagg ttcagaggta ttatggaata 2300

 agaatggttt catagtttgg cttttctata taattcctcc ctctcaaact 2350

 gaaatattca tttttttagt ggagtatttg actagagaga aggtaaggca 2400

 gaaatacagt ctacactggc ttttaaaaat gtaaagccaa tttccaaccg 2450

 gaccccaaat agtacaggtt gaacattccg ttccaacaat ccaaaacccc 2500

 aaatgctcca aaatcttaaa ctttgagttc cagcattccg tcagaagtgg 2550

 aaaattttac acctgacctc atttgacagg tggcagttac agtgcaatca 2600

 aaactttgtt ccatgcccaa gattattaaa aatattggat aaaattacct 2650

 tcaagctatg ttgtataagg tgtatataaa acaaatgaat tttgtgttta 2700

 gacttgggtc tactcccaag atacctcatt atatatatac aaaaatcccc 2750

 aaatccaaaa acatttgaaa cacttctggt cccacacatt ttggataagg 2800

 gatatttgac ctatatctaa ttatataata agaaaaatgt attttctttt 2850

 tttttttttt tttgagatgg agtttcactc ttgttgtcgc ccaggctgca 2900

 atggcacaat cttggcttac tacaacctcc gcctccctag ttcaagggat 2950

 tctcctgcct cagcctccca ggtagctggg attacaggca tgtgccacca 3000

 tgcctggcta attttgtatt tttagtagag acggggtttc gccatgttgg 3050

 tcagactggt cttgaactcc tgacctcagg tgatccgccc gcctcagcct 3100

 cccaacgtgc tgggattaca ggtgtgagcc accgtacctg gcagaaaatg 3150

 tactttcttt ctcagaaata cttttaaaaa aaattgaagg gtgaggagaa 3200

 aaacatcttg gagaagagga cccattaaaa ctttaaatat ctgtgggaac 3250

 catttttcct gattttccct tttttaacat catggcaaag atgggttttt 3300

 ttccaacaaa atttaattta atatctttcc acttgaagat tttaggtttg 3350

 ttttcaatac ttaatgaata taaaactaaa ggagaaaagc caacctgaaa 3400

 taatttaaac tttatatgaa catttcgata agagtttgtg gattttttct 3450

 gtagataata tatttgatcc agaactcaag tgcatggaaa catgattttg 3500

 atttttaaaa tctaaaaaaa aaaaaaatta aaatcatgct tccctctatt 3550

 gcagtatcag ttatttagtc acagaatggt attttatgta aattaaaatt 3600

 aggtgaatgc aatgcaggta actggttttg gaatgggaat gtgcagtgct 3650

 ttatgtttgg ggagttggag cagggtatct tttcatcaat tagaaggaaa 3700

 gtttgaaact tctgattacc tttatgttgg tttctcttat tatttgtctc 3750

 ttgctagatc tgctaaacca acccagcttg ctcagagatc tcatattgaa 3800

 gcaacataca ggcaatccac atctttcttt ccctttgaag tatagtcatt 3850

 ggatgggatg agggacaggg cctgttgggt tcacagggcc ttgcactgca 3900

 tgggcacata cttaaaagct cttgtgcatg gaatccctgt ctgttagcca 3950

 caggcctctt tagctctata cattcaaaat aactactgta gtagaaaata 4000

 gataagcttc agctgagttg gcttttgata gtggaaaaaa aacaaaattt 4050

 gactttttat ggccaaaatt ccttgttgac agctgtgatg ttctaatatg 4100

 atttgggaat atgtcagtct acagaacctg catcctgtaa aaacaccttt 4150

 ggggtagacg ataaaagtca tttttaaggc aaatacttac catgtgactt 4200

 tttattacca aatgcatcag tagtggagct ggtatgttgt ttcataggat 4250

 ggaaacatta gaagtccaga gaaaaataaa ttttaaaaaa aggtggaaaa 4300

 gttacggcaa acctgagatt tcagcataaa atctttagta tgaagtgaga 4350

 gaaagaagag ggaggctggt tctgttgctc gtatcaatag gttatctgtg 4400

 tccctcatct tggtgttaca gtgttatttc tgtcagtatt atgaatatgt 4450

 ggttgaccca tcctgtcaaa tgtaccaaca ttttcgaaag aattcattca 4500

 aatctcttat gccaacagaa aagttccttc ttgtttaata tctctttacc 4550

 tcagtcctac attttgattc tctggaggag attttagctt gtcttaaaaa 4600

 gccaaatttg gagtcatcaa gcctgctgaa cctgatgggg cagctttttg 4650

 aacagctttc tggaagtaag aacttcagtt gaaaagccct ttgatcgctt 4700

 cagcccggga catgcccttc agatggctta ttctcagtaa agctttatgt 4750

 agactgtgac actgtatatg tgtgactcgt acaactttga cgtgtttctg 4800

 aagtggttta atcgtatttg ttattagctt ctttgtggaa atgcaatttt 4850

 tatactaaaa acattgctta tttgcaatgc aatatgttat aaatttgttg 4900

 tttatattac tggtattagt cttagcctaa tgaacctaat tatttttctt 4950

 tctgtattct ttgcttcctc aaatagcatc tgcagcaatt ggaatgagaa 5000

 atccagatat gtgtttcaag tagtacattg cctgaatcac aaatcacttg 5050

 atcacagtat tgtatataat ccctgatcct atttgtttca ttttattgta 5100

 aattcccatt tgcatcaaaa cctaatgata gtgattggta agtaaaaaca 5150

 aatggtgtat tgcttttcat acaagtgttt tcacaaaagc catttgccta 5200

 ggcagcaaaa aatattaatt tgtt 5224

<210> 394
<211> 3583
<212> DNA
<213> Homo sapien

<400> 394
 cgcggacccg gccggcccag gcccgcgccc gccgcggccc tgagaggccc 50

 cggcaggtcc cggcccggcg gcggcagcca tggccggggg gccgggcccg 100

 ggggagcccg cagcccccgg cgcccagcac ttcttgtacg aggtgccgcc 150

 ctgggtcatg tgccgcttct acaaagtgat ggacgccctg gagcccgccg 200

 actggtgcca gttcgccgcc ctgatcgtgc gcgaccagac cgagctgcgg 250

 ctgtgcgagc gctccgggca gcgcacggcc agcgtcctgt ggccctggat 300

 caaccgcaac gcccgtgtgg ccgacctcgt gcacatcctc acgcacctgc 350

 agctgctccg tgcgcgggac atcatcacag cctggcaccc tcccgccccg 400

 cttccgtccc caggcaccac tgccccgagg cccagcagca tccctgcacc 450

 cgccgaggcc gaggcctgga gcccccggaa gttgccatcc tcagcctcca 500

 ccttcctctc cccagctttt ccaggctccc agacccattc agggcctgag 550

 ctcggcctgg ttccaagccc tgcttccctg tggcctccac cgccatctcc 600

 agccccttct tctaccaagc caggcccaga gagctcagtg tccctcctgc 650

 agggagcccg cccctctccg ttttgctggc ccctctgtga gatttcccgg 700

 ggcacccaca acttctcgga ggagctcaag atcggggagg gtggctttgg 750

 gtgcgtgtac cgggcggtga tgaggaacac ggtgtatgct gtgaagaggc 800

 tgaaggagaa cgctgacctg gagtggactg cagtgaagca gagcttcctg 850

 accgaggtgg agcagctgtc caggtttcgt cacccaaaca ttgtggactt 900

 tgctggctac tgtgctcaga acggcttcta ctgcctggtg tacggcttcc 950

 tgcccaacgg ctccctggag gaccgtctcc actgccagac ccaggcctgc 1000

 ccacctctct cctggcctca gcgactggac atccttctgg gtacagcccg 1050

 ggcaattcag tttctacatc aggacagccc cagcctcatc catggagaca 1100

 tcaagagttc caacgtcctt ctggatgaga ggctgacacc caagctggga 1150

 gactttggcc tggcccggtt cagccgcttt gccgggtcca gccccagcca 1200

 gagcagcatg gtggcccgga cacagacagt gcggggcacc ctggcctacc 1250

 tgcccgagga gtacatcaag acgggaaggc tggctgtgga cacggacacc 1300

 ttcagctttg gggtggtagt gctagagacc ttggctggtc agagggctgt 1350

 gaagacgcac ggtgccagga ccaagtatct gaaagacctg gtggaagagg 1400

 aggctgagga ggctggagtg gctttgagaa gcacccagag cacactgcaa 1450

 gcaggtctgg ctgcagatgc ctgggctgct cccatcgcca tgcagatcta 1500

 caagaagcac ctggacccca ggcccgggcc ctgcccacct gagctgggcc 1550

 tgggcctggg ccagctggcc tgctgctgcc tgcaccgccg ggccaaaagg 1600

 aggcctccta tgacccaggt gtacgagagg ctagagaagc tgcaggcagt 1650

 ggtggcgggg gtgcccgggc atttggaggc cgccagctgc atcccccctt 1700

 ccccgcagga gaactcctac gtgtccagca ctggcagagc ccacagtggg 1750

 gctgctccat ggcagcccct ggcagcgcca tcaggagcca gtgcccaggc 1800

 agcagagcag ctgcagagag gccccaacca gcccgtggag agtgacgaga 1850

 gcctaggcgg cctctctgct gccctgcgct cctggcactt gactccaagc 1900

 tgccctctgg acccagcacc cctcagggag gccggctgtc ctcaggggga 1950

 cacggcagga gaatcgagct gggggagtgg cccaggatcc cggcccacag 2000

 ccgtggaagg actggccctt ggcagctctg catcatcgtc gtcagagcca 2050

 ccgcagatta tcatcaaccc tgcccgacag aagatggtcc agaagctggc 2100

 cctgtacgag gatggggccc tggacagcct gcagctgctg tcgtccagct 2150

 ccctcccagg cttgggcctg gaacaggaca ggcaggggcc cgaagaaagt 2200

 gatgaatttc agagctgatg tgttcacctg ggcagatccc ccaaatccgg 2250

 aagtcaaagt tctcatggtc agaagttctc atggtgcacg agtcctcagc 2300

 actctgccgg cagtgggggt gggggcccat gcccgcgggg gagagaagga 2350

 ggtggccctg ctgttctagg ctctgtgggc ataggcaggc agagtggaac 2400

 cctgcctcca tgccagcatc tgggggcaag gaaggctggc atcatccagt 2450

 gaggaggctg gcgcatgttg ggaggctgct ggctgcacag acccgtgagg 2500

 ggaggagagg ggctgctgtg caggggtgtg gagtagggag ctggctcccc 2550

 tgagagccat gcagggcgtc tgcagcccag gcctctggca gcagctcttt 2600

 gcccatctct ttggacagtg gccaccctgc acaatggggc cgacgaggcc 2650

 tagggccctc ctacctgctt acaatttgga aaagtgtggc cgggtgcggt 2700

 ggctcacgcc tgtaatccca gcactttggg aggccaaggc aggaggatcg 2750

 ctggagccca gtaggtcaag accagccagg gcaacatgat gagaccctgt 2800

 ctctgccaaa aaatttttta aactattagc ctggcgtggt agcgcacgcc 2850

 tgtggtccca gctgctgggg aggctgaagt aggaggatca tttatgcttg 2900

 ggaggtcgag gctgcagtga gtcatgattg tatgactgca ctccagcctg 2950

 ggtgacagag caagaccctg tttcaaaaag aaaaaccctg ggaaaagtga 3000

 agtatggctg taagtctcat ggttcagtcc tagcaagaag cgagaattct 3050

 gagatcctcc agaaagtcga gcagcaccca cctccaacct cgggccagtg 3100

 tcttcaggct ttactgggga cctgcgagct ggcctaatgt ggtggcctgc 3150

 aagccaggcc atccctgggc gccacagacg agctccgagc caggtcaggc 3200

 ttcggaggcc acaagctcag cctcaggccc aggcactgat tgtggcagag 3250

 gggccactac ccaaggtcta gctaggccca agacctagtt acccagacag 3300

 tgagaagccc ctggaaggca gaaaagttgg gagcatggca gacagggaag 3350

 ggaaacattt tcagggaaaa gacatgtatc acatgtcttc agaagcaagt 3400

 caggtttcat gtaaccgagt gtcctcttgc gtgtccaaaa gtagcccagg 3450

 gctgtagcac aggcttcaca gtgattttgt gttcagccgt gagtcacact 3500

 acatgccccc gtgaagctgg gcattggtga cgtccaggtt gtccttgagt 3550

 aataaaaacg tatgttccct aaaaaaaaaa aaa 3583

<210> 395
<211> 712
<212> PRT
<213> Homo sapien

<400> 395
 Met Ala Gly Gly Pro Gly Pro Gly Glu Pro Ala Ala Pro Gly Ala
   1               5                  10                  15

 Gln His Phe Leu Tyr Glu Val Pro Pro Trp Val Met Cys Arg Phe
                  20                  25                  30

 Tyr Lys Val Met Asp Ala Leu Glu Pro Ala Asp Trp Cys Gln Phe
                  35                  40                  45

 Ala Ala Leu Ile Val Arg Asp Gln Thr Glu Leu Arg Leu Cys Glu
                  50                  55                  60

 Arg Ser Gly Gln Arg Thr Ala Ser Val Leu Trp Pro Trp Ile Asn
                  65                  70                  75

 Arg Asn Ala Arg Val Ala Asp Leu Val His Ile Leu Thr His Leu
                  80                  85                  90

 Gln Leu Leu Arg Ala Arg Asp Ile Ile Thr Ala Trp His Pro Pro
                  95                 100                 105

 Ala Pro Leu Pro Ser Pro Gly Thr Thr Ala Pro Arg Pro Ser Ser
                 110                 115                 120

 Ile Pro Ala Pro Ala Glu Ala Glu Ala Trp Ser Pro Arg Lys Leu
                 125                 130                 135

 Pro Ser Ser Ala Ser Thr Phe Leu Ser Pro Ala Phe Pro Gly Ser
                 140                 145                 150

 Gln Thr His Ser Gly Pro Glu Leu Gly Leu Val Pro Ser Pro Ala
                 155                 160                 165

 Ser Leu Trp Pro Pro Pro Pro Ser Pro Ala Pro Ser Ser Thr Lys
                 170                 175                 180

 Pro Gly Pro Glu Ser Ser Val Ser Leu Leu Gln Gly Ala Arg Pro
                 185                 190                 195

 Ser Pro Phe Cys Trp Pro Leu Cys Glu Ile Ser Arg Gly Thr His
                 200                 205                 210

 Asn Phe Ser Glu Glu Leu Lys Ile Gly Glu Gly Gly Phe Gly Cys
                 215                 220                 225

 Val Tyr Arg Ala Val Met Arg Asn Thr Val Tyr Ala Val Lys Arg
                 230                 235                 240

 Leu Lys Glu Asn Ala Asp Leu Glu Trp Thr Ala Val Lys Gln Ser
                 245                 250                 255

 Phe Leu Thr Glu Val Glu Gln Leu Ser Arg Phe Arg His Pro Asn
                 260                 265                 270

 Ile Val Asp Phe Ala Gly Tyr Cys Ala Gln Asn Gly Phe Tyr Cys
                 275                 280                 285

 Leu Val Tyr Gly Phe Leu Pro Asn Gly Ser Leu Glu Asp Arg Leu
                 290                 295                 300

 His Cys Gln Thr Gln Ala Cys Pro Pro Leu Ser Trp Pro Gln Arg
                 305                 310                 315

 Leu Asp Ile Leu Leu Gly Thr Ala Arg Ala Ile Gln Phe Leu His
                 320                 325                 330

 Gln Asp Ser Pro Ser Leu Ile His Gly Asp Ile Lys Ser Ser Asn
                 335                 340                 345

 Val Leu Leu Asp Glu Arg Leu Thr Pro Lys Leu Gly Asp Phe Gly
                 350                 355                 360

 Leu Ala Arg Phe Ser Arg Phe Ala Gly Ser Ser Pro Ser Gln Ser
                 365                 370                 375

 Ser Met Val Ala Arg Thr Gln Thr Val Arg Gly Thr Leu Ala Tyr
                 380                 385                 390

 Leu Pro Glu Glu Tyr Ile Lys Thr Gly Arg Leu Ala Val Asp Thr
                 395                 400                 405

 Asp Thr Phe Ser Phe Gly Val Val Val Leu Glu Thr Leu Ala Gly
                 410                 415                 420

 Gln Arg Ala Val Lys Thr His Gly Ala Arg Thr Lys Tyr Leu Lys
                 425                 430                 435

 Asp Leu Val Glu Glu Glu Ala Glu Glu Ala Gly Val Ala Leu Arg
                 440                 445                 450

 Ser Thr Gln Ser Thr Leu Gln Ala Gly Leu Ala Ala Asp Ala Trp
                 455                 460                 465

 Ala Ala Pro Ile Ala Met Gln Ile Tyr Lys Lys His Leu Asp Pro
                 470                 475                 480

 Arg Pro Gly Pro Cys Pro Pro Glu Leu Gly Leu Gly Leu Gly Gln
                 485                 490                 495

 Leu Ala Cys Cys Cys Leu His Arg Arg Ala Lys Arg Arg Pro Pro
                 500                 505                 510

 Met Thr Gln Val Tyr Glu Arg Leu Glu Lys Leu Gln Ala Val Val
                 515                 520                 525

 Ala Gly Val Pro Gly His Leu Glu Ala Ala Ser Cys Ile Pro Pro
                 530                 535                 540

 Ser Pro Gln Glu Asn Ser Tyr Val Ser Ser Thr Gly Arg Ala His
                 545                 550                 555

 Ser Gly Ala Ala Pro Trp Gln Pro Leu Ala Ala Pro Ser Gly Ala
                 560                 565                 570

 Ser Ala Gln Ala Ala Glu Gln Leu Gln Arg Gly Pro Asn Gln Pro
                 575                 580                 585

 Val Glu Ser Asp Glu Ser Leu Gly Gly Leu Ser Ala Ala Leu Arg
                 590                 595                 600

 Ser Trp His Leu Thr Pro Ser Cys Pro Leu Asp Pro Ala Pro Leu
                 605                 610                 615

 Arg Glu Ala Gly Cys Pro Gln Gly Asp Thr Ala Gly Glu Ser Ser
                 620                 625                 630

 Trp Gly Ser Gly Pro Gly Ser Arg Pro Thr Ala Val Glu Gly Leu
                 635                 640                 645

 Ala Leu Gly Ser Ser Ala Ser Ser Ser Ser Glu Pro Pro Gln Ile
                 650                 655                 660

 Ile Ile Asn Pro Ala Arg Gln Lys Met Val Gln Lys Leu Ala Leu
                 665                 670                 675

 Tyr Glu Asp Gly Ala Leu Asp Ser Leu Gln Leu Leu Ser Ser Ser
                 680                 685                 690

 Ser Leu Pro Gly Leu Gly Leu Glu Gln Asp Arg Gln Gly Pro Glu
                 695                 700                 705

 Glu Ser Asp Glu Phe Gln Ser
                 710

<210> 396
<211> 647
<212> DNA
<213> Homo sapien

<400> 396
 gctcactgag caccgtccca gcatccggac accacagcgg cccttcgctc 50

 cacgcagaaa accacacttc tcataccttc actcaacact tccttcccca 100

 aagccagaag atgcacaagg aggaacatga ggtggctgtg ctgggggcac 150

 cccccagcac catccttcca aggtccaccg tgattaacat ccacagcgag 200

 acctccgtgc ccgaccatgt cgtctggtcc ctgttcaaca ccctcttctt 250

 gaactggtgc tgtctgggct tcatagcatt cgcctactcc gtaaagtcta 300

 gggacaggaa gatggttggc gacgtgaccg gggcccaggc ctatgcctcc 350

 accgccaagt gcctgaacat ctgggccctg attctgggca tcctcatgac 400

 cattggattc atcctgttac tggtattcgg ctctgtaaca gtctaccata 450

 ttatgttaca gataatacag gaaaaacggg gttactagta gccgcccata 500

 gcctgcaacc tttgcactcc actgtgcaat gctggccctg cacgctgggg 550

 ctgttgcccc tgcccccttg gtcctgcccc tagatacagc agtttatacc 600

 cacacacctg tctacagtgt cattcaataa agtgcacgtg cttgtga 647

<210> 397
<211> 125
<212> PRT
<213> Homo sapien

<400> 397
 Met His Lys Glu Glu His Glu Val Ala Val Leu Gly Ala Pro Pro
   1               5                  10                  15

 Ser Thr Ile Leu Pro Arg Ser Thr Val Ile Asn Ile His Ser Glu
                  20                  25                  30

 Thr Ser Val Pro Asp His Val Val Trp Ser Leu Phe Asn Thr Leu
                  35                  40                  45

 Phe Leu Asn Trp Cys Cys Leu Gly Phe Ile Ala Phe Ala Tyr Ser
                  50                  55                  60

 Val Lys Ser Arg Asp Arg Lys Met Val Gly Asp Val Thr Gly Ala
                  65                  70                  75

 Gln Ala Tyr Ala Ser Thr Ala Lys Cys Leu Asn Ile Trp Ala Leu
                  80                  85                  90

 Ile Leu Gly Ile Leu Met Thr Ile Gly Phe Ile Leu Leu Leu Val
                  95                 100                 105

 Phe Gly Ser Val Thr Val Tyr His Ile Met Leu Gln Ile Ile Gln
                 110                 115                 120

 Glu Lys Arg Gly Tyr
                 125

<210> 398
<211> 2122
<212> DNA
<213> Homo sapien

<400> 398
 gcccgtcccg ccgcccgccc gccagccatg agctccacgc agttcaacaa 50

 gggcccctcg tacgggctgt cggccgaggt caagaaccgg ctcctgtcca 100

 aatatgaccc ccagaaggag gcagagctcc gcacctggat cgagggactc 150

 accggcctct ccatcggccc cgacttccag aagggcctga aggatggaac 200

 tatcttatgc acactcatga acaagctaca gccgggctcc gtccccaaga 250

 tcaaccgctc catgcagaac tggcaccagc tagaaaacct gtccaacttc 300

 atcaaggcca tggtcagcta cggcatgaac cctgtggacc tgttcgaggc 350

 caacgacctg tttgagagtg ggaacatgac gcaggtgcag gtgtctcttc 400

 tcgccctggc ggggaaggcc aagactaagg ggctgcagag cggggtggac 450

 attggcgtca agtactcgga gaagcaggag cggaatttcg acgatgccac 500

 catgaaggct ggccagtgcg tcatcgggct gcagatgggc accaacaaat 550

 gcgccagcca gtcgggcatg actgcctacg gcacgagaag gcatctctat 600

 gaccccaaga accatatcct gccccccatg gaccactcga ccatcagcct 650

 ccagatgggc acgaacaagt gcgccagcca ggtgggcatg acggctcccg 700

 ggacccggcg gcacatctat gataccaagc tgggaaccga caagtgtgac 750

 aactcctcca tgtccctgca gatgggctac acgcagggcg ccaaccagag 800

 cggccaggtc ttcggcctgg gccggcagat atatgacccc aagtactgcc 850

 cgcaaggcac agtggccgat ggggctccct cgggcaccgg cgactgcccg 900

 gacccggggg aggtccctga atatccccct tactaccagg aggaggccgg 950

 ctactgaggc tcccagcacg ctctctcccc acatcgtctt cccatctggg 1000

 tttttgggtt tttctgtgtt ttcatctttt tttttttttt tcttgacccg 1050

 ttcagtgctg ccagtcaacc aagggtctgt gagtgtcagc gtgggatcag 1100

 gcagcagagc ttttttcccc tttgccttga tccttcgcaa ggctgagcca 1150

 ctgggctgtg ggggaagggg tcaaggccat atcccaatac gtgtagggcg 1200

 agggtccctg ctggcacatt caggctgtgc tgggaagaag agacctgggc 1250

 ttggaaggaa ccggtccccg acggtttctg gttgcctcgc ctcttccccc 1300

 ttttgtcagc tgagcagttt gtggtttcta tgcccgcaag tttcaggaag 1350

 tattcacaaa agaaaaatac attttttccc ccaggggtgg ggcaaggaca 1400

 gtggagagag tgctaggaaa tgagtcccct gggaaagggg accgggccgt 1450

 gatgttaaat atctccggct cccaagtgac tggatttgcc taggaccttc 1500

 agatcaacag acttcagacc ctcagacctg ccccggggcc aggtggagaa 1550

 agtgagggcc gtacaaggaa gtgaaattct gagttgttgg ggctaagcct 1600

 gaccccctct ccatgctccc cgccccaact cactctggcc tcagtagatt 1650

 tttttttcag ttgtggttgt tgcccaggct ggagtgcagt ggcgccatct 1700

 tggctcactg cacctccacc ttccgggctc aagcgattct ccagcctcag 1750

 cctcctgagt agctaggact gcaggtgctc caccacgccc ggctaatttt 1800

 tgtattttta gtagagatgg ggtttcccca tgttggccag gctggtctcg 1850

 aactcctggc ctcaggtgtg atccgcccgc ctccgcctcc ccaagcgctg 1900

 agattacagg tgtgagccac cgtgcccagg ccctcagtag gttttaagga 1950

 gtccccagcc ctcctccctt ctgggcccga ccagcttata ctgctccatc 2000

 ttccccggcc acatgccccg ccaagtactg cacagggacc ccccacccag 2050

 gggccctgct ccgtgagata atgtgaaata cgactgtgga ccaaacgcaa 2100

 taaaaccttt gtttgtagga ag 2122

<210> 399
<211> 309
<212> PRT
<213> Homo sapien

<400> 399
 Met Ser Ser Thr Gln Phe Asn Lys Gly Pro Ser Tyr Gly Leu Ser
   1               5                  10                  15

 Ala Glu Val Lys Asn Arg Leu Leu Ser Lys Tyr Asp Pro Gln Lys
                  20                  25                  30

 Glu Ala Glu Leu Arg Thr Trp Ile Glu Gly Leu Thr Gly Leu Ser
                  35                  40                  45

 Ile Gly Pro Asp Phe Gln Lys Gly Leu Lys Asp Gly Thr Ile Leu
                  50                  55                  60

 Cys Thr Leu Met Asn Lys Leu Gln Pro Gly Ser Val Pro Lys Ile
                  65                  70                  75

 Asn Arg Ser Met Gln Asn Trp His Gln Leu Glu Asn Leu Ser Asn
                  80                  85                  90

 Phe Ile Lys Ala Met Val Ser Tyr Gly Met Asn Pro Val Asp Leu
                  95                 100                 105

 Phe Glu Ala Asn Asp Leu Phe Glu Ser Gly Asn Met Thr Gln Val
                 110                 115                 120

 Gln Val Ser Leu Leu Ala Leu Ala Gly Lys Ala Lys Thr Lys Gly
                 125                 130                 135

 Leu Gln Ser Gly Val Asp Ile Gly Val Lys Tyr Ser Glu Lys Gln
                 140                 145                 150

 Glu Arg Asn Phe Asp Asp Ala Thr Met Lys Ala Gly Gln Cys Val
                 155                 160                 165

 Ile Gly Leu Gln Met Gly Thr Asn Lys Cys Ala Ser Gln Ser Gly
                 170                 175                 180

 Met Thr Ala Tyr Gly Thr Arg Arg His Leu Tyr Asp Pro Lys Asn
                 185                 190                 195

 His Ile Leu Pro Pro Met Asp His Ser Thr Ile Ser Leu Gln Met
                 200                 205                 210

 Gly Thr Asn Lys Cys Ala Ser Gln Val Gly Met Thr Ala Pro Gly
                 215                 220                 225

 Thr Arg Arg His Ile Tyr Asp Thr Lys Leu Gly Thr Asp Lys Cys
                 230                 235                 240

 Asp Asn Ser Ser Met Ser Leu Gln Met Gly Tyr Thr Gln Gly Ala
                 245                 250                 255

 Asn Gln Ser Gly Gln Val Phe Gly Leu Gly Arg Gln Ile Tyr Asp
                 260                 265                 270

 Pro Lys Tyr Cys Pro Gln Gly Thr Val Ala Asp Gly Ala Pro Ser
                 275                 280                 285

 Gly Thr Gly Asp Cys Pro Asp Pro Gly Glu Val Pro Glu Tyr Pro
                 290                 295                 300

 Pro Tyr Tyr Gln Glu Glu Ala Gly Tyr
                 305

<210> 400
<211> 3305
<212> DNA
<213> Homo sapien

<400> 400
 aaaaaaaata tattaataaa aaagttcaaa aaaggggggg gattgtcatc 50

 tcctttgggg tgcgatggct tcaaatccaa actgaggctc tccgggtggt 100

 aaggatgtgc gaggaggcct cttgaagaac tccaggccta tcatgctgtc 150

 tctccgctaa agcctgaggc ccgaggtcag aggattcagg aaggctctgc 200

 agtcggccca ggagggcggg gtcccgtggt ggaggcgggg agagggaagg 250

 accgcacgga gcaccaaccc ctgctcggcc ccgtaccagg aagcgctggg 300

 gggcagagga gcggagttga ggcagaagcc aggtgaggct ggagtcctgg 350

 ggtaggcagg ctgtcgctgc cgctgccgct gcctgagatg gaaatcgggg 400

 gaggaagctc gcggaagaaa cagcggaggg ttcgtggaaa aaaaagcaat 450

 ggctgagcta agggatgggg taccaggtta gggggaggaa acggtagaga 500

 gaaataggtg gggctcccgc gcatgctcaa tagggaaggg gcgcccgtgg 550

 ggtgcggacg catgcgtagt gggcttctcg ggcggtgggg tgggcgcgga 600

 atttggagac ccacttcggg aaaggtaaaa tgcgggcgca attttagggt 650

 acctgtggga cccgggctct tagggtcttg acacaggacg ggcctgggcc 700

 gaaagcccag gcacgcccga ccagagagtg tttctccact cccggactct 750

 gccagtcagg atggtggtgc cttcgctgaa gcttcaggac ctcatcgaag 800

 agattcgcgg ggccaagact caggcccagg agcgggaggt gatccaaaag 850

 gagtgtgccc acatccgggc ctccttccgc gacggggacc cagtgcacag 900

 gcaccggcag ctggccaaac tgctctacgt ccacatgttg ggctaccccg 950

 cccactttgg acagatggag tgcctgaaac tgatcgcctc ctccagattc 1000

 acagacaaga gggtgggcta cctgggggcc atgcttctat tggatgagag 1050

 gcacgatgcc cacctgctca ttaccaacag catcaagaat gacctgagcc 1100

 aggggattca gccagtacaa ggcctggcct tgtgcacttt gagcaccatg 1150

 ggctctgctg agatgtgccg agacctggcc ccagaggtgg agaaactgct 1200

 cctgcagccc agtccctacg tgcgcaagaa ggctattctg actgcagtgc 1250

 acatgatccg gaaggtccct gaactctcca gtgtcttcct cccaccctgt 1300

 gcccaactgc ttcatgagcg tcaccatggc atcctgctgg gcaccatcac 1350

 gctgatcacg gagctctgcg aacgaagccc tgcagccctc aggcacttcc 1400

 gaaaggtggt accccagctg gtacacatcc tccggactct ggtgacaatg 1450

 ggatactcca cagaacacag catatctgga gtcagcgacc ccttcctgca 1500

 ggtccagata cttcgtctgc ttcggatcct gggccggaac cacgaggaga 1550

 gcagtgagac catgaatgac ttgctggccc aggtggccac taacacggac 1600

 accagccgaa atgccggaaa tgcggtcctg tttgagacag tactcaccat 1650

 catggatatc cgctctgcag ctggcctacg ggttctagct gtcaacattc 1700

 ttggtcgctt cctactcaac agtgacagga acattaggta tgtggccctg 1750

 acatcactgc ttcgactggt gcagtctgat cacagtgctg tgcagcggca 1800

 tcggcccact gtggtggaat gtctacggga aactgatgcc tccctcagcc 1850

 ggagagccct ggaactaagc ctggctctgg taaatagctc caatgtgcga 1900

 gccatgatgc aagagctgca ggcctttctg gagtcctgcc ctcctgacct 1950

 acgggctgac tgtgcctcag gcatcctgct ggctgcagag aggtttgctc 2000

 caaccaaacg ctggcacata gacaccatcc tgcatgtgct gacaacggcg 2050

 ggcacccatg tgcgggatga tgcagtggcc aacctgaccc agctgattgg 2100

 gggggcccag gagctacatg cctactctgt gcgccgcctc tacaatgccc 2150

 tggcagaaga catttcccag caaccactgg tgcaggtggc agcctggtgc 2200

 attggggagt atggggacct cctgctggca gggaactgcg aggagattga 2250

 gccccttcag gtggacgaag aggaagtgct ggcattgctg gaaaaggtgc 2300

 tgcagtccca catgtccctg ccagccactc gaggatatgc cctcacagcc 2350

 ctcatgaagc tcagcactcg cctctgtggg gacaacaacc gcatccgcca 2400

 ggtggtgtcc atctacggga gctgcttgga cgtggagctg cagcagcggg 2450

 ctgtggagta tgacacactc ttccggaaat acgaccacat gagggctgcc 2500

 atcctggaaa aaatgcctct tgtggagcga gatggccctc aggctgatga 2550

 ggaagcaaag gaaagcaaag aagcagccca gctttcagaa gcagccccag 2600

 tgcccacaga gccccaggcc tcacagctcc tggatctgct agatctcctg 2650

 gatggggctt ctggggatgt ccagcatcct ccccatctgg acccctcccc 2700

 aggaggtgcc ctggtacacc tgcttgacct tccctgtgta cctccacccc 2750

 cagctcccat cccagatctc aaagtgtttg agcgtgaggg agtacagctg 2800

 aatctgtctt tcattcgacc ccctgaaaac cctgctttgc tgttaatcac 2850

 catcactgcc accaacttct cagagggtga tgtcacccat ttcatctgcc 2900

 aggctgctgt gcccaagagt ctccagctgc agctgcaggc ccccagtggg 2950

 aacacagttc cagctcgggg tggccttcct atcacccagc tcttcagaat 3000

 cctcaatcct aacaaggccc ccctgcggct aaagctgcgc ctcacctacg 3050

 accactttca ccagtcggtg caggagatct ttgaggtgaa caacttgcct 3100

 gtggaatcgt ggcagtaact gtctccactc acagcctgaa attctcctgt 3150

 gtcccaaacc ccagggggcc ccagcagctt cgaacctaca cctgagggct 3200

 accagcaggt ggcgctctgg ctttgcactg caaaaactgg ggaccagccc 3250

 ccttctccca caaataaagc ccaataaagc ctgagaagtg aggaaagcca 3300

 aaaaa 3305

<210> 401
<211> 785
<212> PRT
<213> Homo sapien

<400> 401
 Met Val Val Pro Ser Leu Lys Leu Gln Asp Leu Ile Glu Glu Ile
   1               5                  10                  15

 Arg Gly Ala Lys Thr Gln Ala Gln Glu Arg Glu Val Ile Gln Lys
                  20                  25                  30

 Glu Cys Ala His Ile Arg Ala Ser Phe Arg Asp Gly Asp Pro Val
                  35                  40                  45

 His Arg His Arg Gln Leu Ala Lys Leu Leu Tyr Val His Met Leu
                  50                  55                  60

 Gly Tyr Pro Ala His Phe Gly Gln Met Glu Cys Leu Lys Leu Ile
                  65                  70                  75

 Ala Ser Ser Arg Phe Thr Asp Lys Arg Val Gly Tyr Leu Gly Ala
                  80                  85                  90

 Met Leu Leu Leu Asp Glu Arg His Asp Ala His Leu Leu Ile Thr
                  95                 100                 105

 Asn Ser Ile Lys Asn Asp Leu Ser Gln Gly Ile Gln Pro Val Gln
                 110                 115                 120

 Gly Leu Ala Leu Cys Thr Leu Ser Thr Met Gly Ser Ala Glu Met
                 125                 130                 135

 Cys Arg Asp Leu Ala Pro Glu Val Glu Lys Leu Leu Leu Gln Pro
                 140                 145                 150

 Ser Pro Tyr Val Arg Lys Lys Ala Ile Leu Thr Ala Val His Met
                 155                 160                 165

 Ile Arg Lys Val Pro Glu Leu Ser Ser Val Phe Leu Pro Pro Cys
                 170                 175                 180

 Ala Gln Leu Leu His Glu Arg His His Gly Ile Leu Leu Gly Thr
                 185                 190                 195

 Ile Thr Leu Ile Thr Glu Leu Cys Glu Arg Ser Pro Ala Ala Leu
                 200                 205                 210

 Arg His Phe Arg Lys Val Val Pro Gln Leu Val His Ile Leu Arg
                 215                 220                 225

 Thr Leu Val Thr Met Gly Tyr Ser Thr Glu His Ser Ile Ser Gly
                 230                 235                 240

 Val Ser Asp Pro Phe Leu Gln Val Gln Ile Leu Arg Leu Leu Arg
                 245                 250                 255

 Ile Leu Gly Arg Asn His Glu Glu Ser Ser Glu Thr Met Asn Asp
                 260                 265                 270

 Leu Leu Ala Gln Val Ala Thr Asn Thr Asp Thr Ser Arg Asn Ala
                 275                 280                 285

 Gly Asn Ala Val Leu Phe Glu Thr Val Leu Thr Ile Met Asp Ile
                 290                 295                 300

 Arg Ser Ala Ala Gly Leu Arg Val Leu Ala Val Asn Ile Leu Gly
                 305                 310                 315

 Arg Phe Leu Leu Asn Ser Asp Arg Asn Ile Arg Tyr Val Ala Leu
                 320                 325                 330

 Thr Ser Leu Leu Arg Leu Val Gln Ser Asp His Ser Ala Val Gln
                 335                 340                 345

 Arg His Arg Pro Thr Val Val Glu Cys Leu Arg Glu Thr Asp Ala
                 350                 355                 360

 Ser Leu Ser Arg Arg Ala Leu Glu Leu Ser Leu Ala Leu Val Asn
                 365                 370                 375

 Ser Ser Asn Val Arg Ala Met Met Gln Glu Leu Gln Ala Phe Leu
                 380                 385                 390

 Glu Ser Cys Pro Pro Asp Leu Arg Ala Asp Cys Ala Ser Gly Ile
                 395                 400                 405

 Leu Leu Ala Ala Glu Arg Phe Ala Pro Thr Lys Arg Trp His Ile
                 410                 415                 420

 Asp Thr Ile Leu His Val Leu Thr Thr Ala Gly Thr His Val Arg
                 425                 430                 435

 Asp Asp Ala Val Ala Asn Leu Thr Gln Leu Ile Gly Gly Ala Gln
                 440                 445                 450

 Glu Leu His Ala Tyr Ser Val Arg Arg Leu Tyr Asn Ala Leu Ala
                 455                 460                 465

 Glu Asp Ile Ser Gln Gln Pro Leu Val Gln Val Ala Ala Trp Cys
                 470                 475                 480

 Ile Gly Glu Tyr Gly Asp Leu Leu Leu Ala Gly Asn Cys Glu Glu
                 485                 490                 495

 Ile Glu Pro Leu Gln Val Asp Glu Glu Glu Val Leu Ala Leu Leu
                 500                 505                 510

 Glu Lys Val Leu Gln Ser His Met Ser Leu Pro Ala Thr Arg Gly
                 515                 520                 525

 Tyr Ala Leu Thr Ala Leu Met Lys Leu Ser Thr Arg Leu Cys Gly
                 530                 535                 540

 Asp Asn Asn Arg Ile Arg Gln Val Val Ser Ile Tyr Gly Ser Cys
                 545                 550                 555

 Leu Asp Val Glu Leu Gln Gln Arg Ala Val Glu Tyr Asp Thr Leu
                 560                 565                 570

 Phe Arg Lys Tyr Asp His Met Arg Ala Ala Ile Leu Glu Lys Met
                 575                 580                 585

 Pro Leu Val Glu Arg Asp Gly Pro Gln Ala Asp Glu Glu Ala Lys
                 590                 595                 600

 Glu Ser Lys Glu Ala Ala Gln Leu Ser Glu Ala Ala Pro Val Pro
                 605                 610                 615

 Thr Glu Pro Gln Ala Ser Gln Leu Leu Asp Leu Leu Asp Leu Leu
                 620                 625                 630

 Asp Gly Ala Ser Gly Asp Val Gln His Pro Pro His Leu Asp Pro
                 635                 640                 645

 Ser Pro Gly Gly Ala Leu Val His Leu Leu Asp Leu Pro Cys Val
                 650                 655                 660

 Pro Pro Pro Pro Ala Pro Ile Pro Asp Leu Lys Val Phe Glu Arg
                 665                 670                 675

 Glu Gly Val Gln Leu Asn Leu Ser Phe Ile Arg Pro Pro Glu Asn
                 680                 685                 690

 Pro Ala Leu Leu Leu Ile Thr Ile Thr Ala Thr Asn Phe Ser Glu
                 695                 700                 705

 Gly Asp Val Thr His Phe Ile Cys Gln Ala Ala Val Pro Lys Ser
                 710                 715                 720

 Leu Gln Leu Gln Leu Gln Ala Pro Ser Gly Asn Thr Val Pro Ala
                 725                 730                 735

 Arg Gly Gly Leu Pro Ile Thr Gln Leu Phe Arg Ile Leu Asn Pro
                 740                 745                 750

 Asn Lys Ala Pro Leu Arg Leu Lys Leu Arg Leu Thr Tyr Asp His
                 755                 760                 765

 Phe His Gln Ser Val Gln Glu Ile Phe Glu Val Asn Asn Leu Pro
                 770                 775                 780

 Val Glu Ser Trp Gln
                 785

<210> 402
<211> 1929
<212> DNA
<213> Homo sapien

<400> 402
 acccccgcac ccagctccgc agaccggcgg gcgcgcgcgg gctctggagg 50

 ccacgggcat gatgcttcgg gtcctggtgg gggctgtcct ccctgccatg 100

 ctactggctg ccccaccacc catcaacaag ctggcactgt tcccagataa 150

 gagtgcctgg tgcgaagcca agaacatcac ccagatcgtg ggccacagcg 200

 gctgtgaggc caagtccatc cagaacaggg cgtgcctagg acagtgcttc 250

 agctacagcg tccccaacac cttcccacag tccacagagt ccctggttca 300

 ctgtgactcc tgcatgccag cccagtccat gtgggagatt gtgacgctgg 350

 agtgcccggg ccacgaggag gtgcccaggg tggacaagct ggtggagaag 400

 atcctgcact gtagctgcca ggcctgcggc aaggagccta gtcacgaggg 450

 gctgagcgtc tatgtgcagg gcgaggacgg gccgggatcc cagcccggca 500

 cccaccctca cccccatccc cacccccatc ctggcgggca gacccctgag 550

 cccgaggacc cccctggggc cccccacaca gaggaagagg gggctgagga 600

 ctgaggcccc cccaactctt cctcccctct catccccctg tggaatgttg 650

 ggtctcactc tctggggaag tcaggggaga agctgaagcc cccctttggc 700

 actggatgga cttggcttca gactcggact tgaatgctgc ccggttgcca 750

 tggagatctg aaggggcggg gttagagcca agctgcacaa tttaatatat 800

 tcaagagtgg ggggaggaag cagaggtctt cagggctctt tttttggggg 850

 gggggtggtc tcttcctgtc tggcttctag agatgtgcct gtgggagggg 900

 gaggaagttg gctgagccat tgagtgctgg gggaggccat ccaagatggc 950

 atgaatcggg ctaaggtccc tgggggtgca gatggtactg ctgaggtccc 1000

 gggcttagtg tgagcatctt gccagcctca ggcttgaggg agggctgggc 1050

 tagaaagacc actggcagaa acaggaggct ccggccccac aggtttcccc 1100

 aaggcctctc accccacttc ccatctccag ggaagcgtcg ccccagtggc 1150

 actgaagtgg ccctccctca gcggaggggt ttgggagtca ggcctgggca 1200

 ggaccctgct gactcgtggc gcgggagctg ggagccaggc tctccgggcc 1250

 tttctctggc ttccttggct tgcctggtgg gggaagggga ggaggggaag 1300

 aaggaaaggg aagagtcttc caaggccaga gggaggggga caacccccca 1350

 agaccatccc tgaagacgag catccccctc ctctccctgt tagaaatgtt 1400

 agtgccccgc actgtgcccc aagttctagg ccccccagaa agctgtcaga 1450

 gccggccgcc ttctcccctc tcccagggat gctctttgta aatatcggat 1500

 gggtgtggga gtgaggggtt acctccctcg ccccaaggtt ccagaggccc 1550

 taggcgggat gggctcgctg aacctcgagg aactccagga cgaggaggac 1600

 atgggacttg cgtggacagt cagggttcac ttgggctctc tctagctccc 1650

 caattctgcc tgcctcctcc ctcccagctg cactttaacc ctagaaggtg 1700

 gggacctggg gggagggaca gggcaggcgg gcccatgaag aaagcccctc 1750

 gttgcccagc actgtctgcg tctgctcttc tgtgcccagg gtggctgcca 1800

 gcccactgcc tcctgcctgg ggtggcctgg ccctcctggc tgttgcgacg 1850

 cgggcttctg gagcttgtca ccattggaca gtctccctga tggaccctca 1900

 gtcttctcat gaataaattc ttcggaatt 1929

<210> 403
<211> 180
<212> PRT
<213> Homo sapien

<400> 403
 Met Leu Arg Val Leu Val Gly Ala Val Leu Pro Ala Met Leu Leu
   1               5                  10                  15

 Ala Ala Pro Pro Pro Ile Asn Lys Leu Ala Leu Phe Pro Asp Lys
                  20                  25                  30

 Ser Ala Trp Cys Glu Ala Lys Asn Ile Thr Gln Ile Val Gly His
                  35                  40                  45

 Ser Gly Cys Glu Ala Lys Ser Ile Gln Asn Arg Ala Cys Leu Gly
                  50                  55                  60

 Gln Cys Phe Ser Tyr Ser Val Pro Asn Thr Phe Pro Gln Ser Thr
                  65                  70                  75

 Glu Ser Leu Val His Cys Asp Ser Cys Met Pro Ala Gln Ser Met
                  80                  85                  90

 Trp Glu Ile Val Thr Leu Glu Cys Pro Gly His Glu Glu Val Pro
                  95                 100                 105

 Arg Val Asp Lys Leu Val Glu Lys Ile Leu His Cys Ser Cys Gln
                 110                 115                 120

 Ala Cys Gly Lys Glu Pro Ser His Glu Gly Leu Ser Val Tyr Val
                 125                 130                 135

 Gln Gly Glu Asp Gly Pro Gly Ser Gln Pro Gly Thr His Pro His
                 140                 145                 150

 Pro His Pro His Pro His Pro Gly Gly Gln Thr Pro Glu Pro Glu
                 155                 160                 165

 Asp Pro Pro Gly Ala Pro His Thr Glu Glu Glu Gly Ala Glu Asp
                 170                 175                 180

<210> 404
<211> 2271
<212> DNA
<213> Homo sapien

<400> 404
 tggccggaat tccggggagg gagaagcccc tttggcctgc cttacggaag 50

 cctgcgaggg agggtggtgt ccactgccca gttccgtgtc ccgatgccca 100

 gcgccacgca gcgcaagagt caggagaagc cgcgggagat catggacgcg 150

 gcggaagatt atgctaaaga gagatatgga atatcttcaa tgatacaatc 200

 acaagaaaaa ccagatcgag ttttggttcg ggttagagac ttgacaatac 250

 aaaaagctga tgaagttgtt tgggtacgtg caagagttca tacaagcaga 300

 gctaaaggga aacagtgctt cttagtccta cgtcagcagc agtttaatgt 350

 ccaggctctt gtggcggtgg gagaccatgc aagcaagcag atggttaaat 400

 ttgctgccaa catcaacaaa gagagcattg tggatgtaga aggtgttgtg 450

 agaaaagtga atcagaaaat tggaagctgt acacagcaag acgttgagtt 500

 acatgttcag aagatttatg tgatcagttt ggctgaaccc cgtctgcccc 550

 tgcagctgga tgatgctgtt cggcctgagc aagaaggaga agaggaagga 600

 agagctactg ttaaccagga tacaagatta gacaacagag tcattgatct 650

 taggacatca actagtcagg cagtcttccg tctccagtct ggcatctgcc 700

 atctcttccg agaaacttta attaacaaag gttttgtgga aatccaaact 750

 cctaaaatta tttcagctgc cagtgaagga ggagccaatg tttttactgt 800

 gtcatatttt aaaaataatg catacctggc tcagtcccca cagctatata 850

 agcaaatgtg catttgtgct gattttgaga aggttttctc tattggacca 900

 gtattcagag cggaagactc taatacccat agacatctaa ctgagtttgt 950

 tggtttggac attgaaatgg cttttaatta ccattaccac gaagttatgg 1000

 aagaaattgc tgacaccatg gtacaaatat tcaaaggact tcaagaaagg 1050

 tttcagactg aaattcaaac agtgaataaa cagttcccat gtgagccatt 1100

 caaatttttg gagccaactc taagactaga atattgtgaa gcattggcta 1150

 tgcttaggga agctggagtc gaaatgggag atgaagacga tctgagcaca 1200

 ccaaatgaaa agctgttggg tcatttggta aaggaaaagt atgatacaga 1250

 tttttatatt cttgataaat atccattggc tgtaagacct ttctatacca 1300

 tgcctgaccc aagaaatccc aaacagtcca agtcttacga tatgttcatg 1350

 agaggagaag aaatattgtc aggagctcaa agaatacatg atcctcaact 1400

 gctaacagag agagctttac atcatggaaa tgatttggag aaaattaagg 1450

 cttacattga ttccttccgc tttggagccc ctcctcatgc tggtggaggc 1500

 attggattgg aacgagttac tatgctgttt ctgggattgc ataatgttcg 1550

 tcagacctcc atgttccctc gtgatcccaa acgactcact ccttaaattc 1600

 acactttgcc acttaactcc agtgtggatg acagagcgag accctgcctc 1650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aaaaaaaaaa aagaaagcca cacttattct tttcagtaac ctgctagtgc 1750

 acaggctgta ctttaggtac ttaaaatatg cactagaata aatttgcaag 1800

 gccctaaaat atcactgtta tttttggagt aattcagtat aggttcgttt 1850

 aaaagagatt tttataactt cagacatgca tcagtaggaa ataacttgag 1900

 aaattcatat ggttatgtta caaattcata ttctgttact acagtaaacg 1950

 ttaagagttt taaacagtta agattgtaca atttttcttc ttttctatat 2000

 tacaagggcc ccagtgttaa tgtcttagat tttcagtatt tgaacttatt 2050

 tttttaaatt ctgtcattga gataagaata attcaggtag catctgaaat 2100

 tttaatgaat gtataattgg catatcatgg aaaattaacc agaaagtatc 2150

 agttcttaaa agttatgcct agaaattatg taaagctaaa ctactggtta 2200

 gaaagtattc agtgtaatat tgtattaatt tgttaaattc taaacttgaa 2250

 tttcaataaa attttaaagc t 2271

<210> 405
<211> 500
<212> PRT
<213> Homo sapien

<400> 405
 Met Pro Ser Ala Thr Gln Arg Lys Ser Gln Glu Lys Pro Arg Glu
   1               5                  10                  15

 Ile Met Asp Ala Ala Glu Asp Tyr Ala Lys Glu Arg Tyr Gly Ile
                  20                  25                  30

 Ser Ser Met Ile Gln Ser Gln Glu Lys Pro Asp Arg Val Leu Val
                  35                  40                  45

 Arg Val Arg Asp Leu Thr Ile Gln Lys Ala Asp Glu Val Val Trp
                  50                  55                  60

 Val Arg Ala Arg Val His Thr Ser Arg Ala Lys Gly Lys Gln Cys
                  65                  70                  75

 Phe Leu Val Leu Arg Gln Gln Gln Phe Asn Val Gln Ala Leu Val
                  80                  85                  90

 Ala Val Gly Asp His Ala Ser Lys Gln Met Val Lys Phe Ala Ala
                  95                 100                 105

 Asn Ile Asn Lys Glu Ser Ile Val Asp Val Glu Gly Val Val Arg
                 110                 115                 120

 Lys Val Asn Gln Lys Ile Gly Ser Cys Thr Gln Gln Asp Val Glu
                 125                 130                 135

 Leu His Val Gln Lys Ile Tyr Val Ile Ser Leu Ala Glu Pro Arg
                 140                 145                 150

 Leu Pro Leu Gln Leu Asp Asp Ala Val Arg Pro Glu Gln Glu Gly
                 155                 160                 165

 Glu Glu Glu Gly Arg Ala Thr Val Asn Gln Asp Thr Arg Leu Asp
                 170                 175                 180

 Asn Arg Val Ile Asp Leu Arg Thr Ser Thr Ser Gln Ala Val Phe
                 185                 190                 195

 Arg Leu Gln Ser Gly Ile Cys His Leu Phe Arg Glu Thr Leu Ile
                 200                 205                 210

 Asn Lys Gly Phe Val Glu Ile Gln Thr Pro Lys Ile Ile Ser Ala
                 215                 220                 225

 Ala Ser Glu Gly Gly Ala Asn Val Phe Thr Val Ser Tyr Phe Lys
                 230                 235                 240

 Asn Asn Ala Tyr Leu Ala Gln Ser Pro Gln Leu Tyr Lys Gln Met
                 245                 250                 255

 Cys Ile Cys Ala Asp Phe Glu Lys Val Phe Ser Ile Gly Pro Val
                 260                 265                 270

 Phe Arg Ala Glu Asp Ser Asn Thr His Arg His Leu Thr Glu Phe
                 275                 280                 285

 Val Gly Leu Asp Ile Glu Met Ala Phe Asn Tyr His Tyr His Glu
                 290                 295                 300

 Val Met Glu Glu Ile Ala Asp Thr Met Val Gln Ile Phe Lys Gly
                 305                 310                 315

 Leu Gln Glu Arg Phe Gln Thr Glu Ile Gln Thr Val Asn Lys Gln
                 320                 325                 330

 Phe Pro Cys Glu Pro Phe Lys Phe Leu Glu Pro Thr Leu Arg Leu
                 335                 340                 345

 Glu Tyr Cys Glu Ala Leu Ala Met Leu Arg Glu Ala Gly Val Glu
                 350                 355                 360

 Met Gly Asp Glu Asp Asp Leu Ser Thr Pro Asn Glu Lys Leu Leu
                 365                 370                 375

 Gly His Leu Val Lys Glu Lys Tyr Asp Thr Asp Phe Tyr Ile Leu
                 380                 385                 390

 Asp Lys Tyr Pro Leu Ala Val Arg Pro Phe Tyr Thr Met Pro Asp
                 395                 400                 405

 Pro Arg Asn Pro Lys Gln Ser Lys Ser Tyr Asp Met Phe Met Arg
                 410                 415                 420

 Gly Glu Glu Ile Leu Ser Gly Ala Gln Arg Ile His Asp Pro Gln
                 425                 430                 435

 Leu Leu Thr Glu Arg Ala Leu His His Gly Asn Asp Leu Glu Lys
                 440                 445                 450

 Ile Lys Ala Tyr Ile Asp Ser Phe Arg Phe Gly Ala Pro Pro His
                 455                 460                 465

 Ala Gly Gly Gly Ile Gly Leu Glu Arg Val Thr Met Leu Phe Leu
                 470                 475                 480

 Gly Leu His Asn Val Arg Gln Thr Ser Met Phe Pro Arg Asp Pro
                 485                 490                 495

 Lys Arg Leu Thr Pro
                 500

<210> 406
<211> 2271
<212> DNA
<213> Homo sapien

<400> 406
 tggccggaat tccggggagg gagaagcccc tttggcctgc cttacggaag 50

 cctgcgaggg agggtggtgt ccactgccca gttccgtgtc ccgatgccca 100

 gcgccacgca gcgcaagagt caggagaagc cgcgggagat catggacgcg 150

 gcggaagatt atgctaaaga gagatatgga atatcttcaa tgatacaatc 200

 acaagaaaaa ccagatcgag ttttggttcg ggttagagac ttgacaatac 250

 aaaaagctga tgaagttgtt tgggtacgtg caagagttca tacaagcaga 300

 gctaaaggga aacagtgctt cttagtccta cgtcagcagc agtttaatgt 350

 ccaggctctt gtggcggtgg gagaccatgc aagcaagcag atggttaaat 400

 ttgctgccaa catcaacaaa gagagcattg tggatgtaga aggtgttgtg 450

 agaaaagtga atcagaaaat tggaagctgt acacagcaag acgttgagtt 500

 acatgttcag aagatttatg tgatcagttt ggctgaaccc cgtctgcccc 550

 tgcagctgga tgatgctgtt cggcctgagc aagaaggaga agaggaagga 600

 agagctactg ttaaccagga tacaagatta gacaacagag tcattgatct 650

 taggacatca actagtcagg cagtcttccg tctccagtct ggcatctgcc 700

 atctcttccg agaaacttta attaacaaag gttttgtgga aatccaaact 750

 cctaaaatta tttcagctgc cagtgaagga ggagccaatg tttttactgt 800

 gtcatatttt aaaaataatg catacctggc tcagtcccca cagctatata 850

 agcaaatgtg catttgtgct gattttgaga aggttttctc tattggacca 900

 gtattcagag cggaagactc taatacccat agacatctaa ctgagtttgt 950

 tggtttggac attgaaatgg cttttaatta ccattaccac gaagttatgg 1000

 aagaaattgc tgacaccatg gtacaaatat tcaaaggact tcaagaaagg 1050

 tttcagactg aaattcaaac agtgaataaa cagttcccat gtgagccatt 1100

 caaatttttg gagccaactc taagactaga atattgtgaa gcattggcta 1150

 tgcttaggga agctggagtc gaaatgggag atgaagacga tctgagcaca 1200

 ccaaatgaaa agctgttggg tcatttggta aaggaaaagt atgatacaga 1250

 tttttatatt cttgataaat atccattggc tgtaagacct ttctatacca 1300

 tgcctgaccc aagaaatccc aaacagtcca agtcttacga tatgttcatg 1350

 agaggagaag aaatattgtc aggagctcaa agaatacatg atcctcaact 1400

 gctaacagag agagctttac atcatggaaa tgatttggag aaaattaagg 1450

 cttacattga ttccttccgc tttggagccc ctcctcatgc tggtggaggc 1500

 attggattgg aacgagttac tatgctgttt ctgggattgc ataatgttcg 1550

 tcagacctcc atgttccctc gtgatcccaa acgactcact ccttaaattc 1600

 acactttgcc acttaactcc agtgtggatg acagagcgag accctgcctc 1650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aaaaaaaaaa aagaaagcca cacttattct tttcagtaac ctgctagtgc 1750

 acaggctgta ctttaggtac ttaaaatatg cactagaata aatttgcaag 1800

 gccctaaaat atcactgtta tttttggagt aattcagtat aggttcgttt 1850

 aaaagagatt tttataactt cagacatgca tcagtaggaa ataacttgag 1900

 aaattcatat ggttatgtta caaattcata ttctgttact acagtaaacg 1950

 ttaagagttt taaacagtta agattgtaca atttttcttc ttttctatat 2000

 tacaagggcc ccagtgttaa tgtcttagat tttcagtatt tgaacttatt 2050

 tttttaaatt ctgtcattga gataagaata attcaggtag catctgaaat 2100

 tttaatgaat gtataattgg catatcatgg aaaattaacc agaaagtatc 2150

 agttcttaaa agttatgcct agaaattatg taaagctaaa ctactggtta 2200

 gaaagtattc agtgtaatat tgtattaatt tgttaaattc taaacttgaa 2250

 tttcaataaa attttaaagc t 2271

<210> 407
<211> 500
<212> PRT
<213> Homo sapien

<400> 407
 Met Pro Ser Ala Thr Gln Arg Lys Ser Gln Glu Lys Pro Arg Glu
   1               5                  10                  15

 Ile Met Asp Ala Ala Glu Asp Tyr Ala Lys Glu Arg Tyr Gly Ile
                  20                  25                  30

 Ser Ser Met Ile Gln Ser Gln Glu Lys Pro Asp Arg Val Leu Val
                  35                  40                  45

 Arg Val Arg Asp Leu Thr Ile Gln Lys Ala Asp Glu Val Val Trp
                  50                  55                  60

 Val Arg Ala Arg Val His Thr Ser Arg Ala Lys Gly Lys Gln Cys
                  65                  70                  75

 Phe Leu Val Leu Arg Gln Gln Gln Phe Asn Val Gln Ala Leu Val
                  80                  85                  90

 Ala Val Gly Asp His Ala Ser Lys Gln Met Val Lys Phe Ala Ala
                  95                 100                 105

 Asn Ile Asn Lys Glu Ser Ile Val Asp Val Glu Gly Val Val Arg
                 110                 115                 120

 Lys Val Asn Gln Lys Ile Gly Ser Cys Thr Gln Gln Asp Val Glu
                 125                 130                 135

 Leu His Val Gln Lys Ile Tyr Val Ile Ser Leu Ala Glu Pro Arg
                 140                 145                 150

 Leu Pro Leu Gln Leu Asp Asp Ala Val Arg Pro Glu Gln Glu Gly
                 155                 160                 165

 Glu Glu Glu Gly Arg Ala Thr Val Asn Gln Asp Thr Arg Leu Asp
                 170                 175                 180

 Asn Arg Val Ile Asp Leu Arg Thr Ser Thr Ser Gln Ala Val Phe
                 185                 190                 195

 Arg Leu Gln Ser Gly Ile Cys His Leu Phe Arg Glu Thr Leu Ile
                 200                 205                 210

 Asn Lys Gly Phe Val Glu Ile Gln Thr Pro Lys Ile Ile Ser Ala
                 215                 220                 225

 Ala Ser Glu Gly Gly Ala Asn Val Phe Thr Val Ser Tyr Phe Lys
                 230                 235                 240

 Asn Asn Ala Tyr Leu Ala Gln Ser Pro Gln Leu Tyr Lys Gln Met
                 245                 250                 255

 Cys Ile Cys Ala Asp Phe Glu Lys Val Phe Ser Ile Gly Pro Val
                 260                 265                 270

 Phe Arg Ala Glu Asp Ser Asn Thr His Arg His Leu Thr Glu Phe
                 275                 280                 285

 Val Gly Leu Asp Ile Glu Met Ala Phe Asn Tyr His Tyr His Glu
                 290                 295                 300

 Val Met Glu Glu Ile Ala Asp Thr Met Val Gln Ile Phe Lys Gly
                 305                 310                 315

 Leu Gln Glu Arg Phe Gln Thr Glu Ile Gln Thr Val Asn Lys Gln
                 320                 325                 330

 Phe Pro Cys Glu Pro Phe Lys Phe Leu Glu Pro Thr Leu Arg Leu
                 335                 340                 345

 Glu Tyr Cys Glu Ala Leu Ala Met Leu Arg Glu Ala Gly Val Glu
                 350                 355                 360

 Met Gly Asp Glu Asp Asp Leu Ser Thr Pro Asn Glu Lys Leu Leu
                 365                 370                 375

 Gly His Leu Val Lys Glu Lys Tyr Asp Thr Asp Phe Tyr Ile Leu
                 380                 385                 390

 Asp Lys Tyr Pro Leu Ala Val Arg Pro Phe Tyr Thr Met Pro Asp
                 395                 400                 405

 Pro Arg Asn Pro Lys Gln Ser Lys Ser Tyr Asp Met Phe Met Arg
                 410                 415                 420

 Gly Glu Glu Ile Leu Ser Gly Ala Gln Arg Ile His Asp Pro Gln
                 425                 430                 435

 Leu Leu Thr Glu Arg Ala Leu His His Gly Asn Asp Leu Glu Lys
                 440                 445                 450

 Ile Lys Ala Tyr Ile Asp Ser Phe Arg Phe Gly Ala Pro Pro His
                 455                 460                 465

 Ala Gly Gly Gly Ile Gly Leu Glu Arg Val Thr Met Leu Phe Leu
                 470                 475                 480

 Gly Leu His Asn Val Arg Gln Thr Ser Met Phe Pro Arg Asp Pro
                 485                 490                 495

 Lys Arg Leu Thr Pro
                 500

<210> 408
<211> 2977
<212> DNA
<213> Homo sapien

<400> 408
 gcaggcgctg cggccgtccc gggccgtgac tcctcctttc ccccgccccg 50

 cctccgttcg gagagccggc gggcgggcgc ctctcggcca ggaagcgcct 100

 cttggacgcg tgtgaccgat gcccagattg cacgaccact tctggagctg 150

 ctcctgtgcg cacagcgcga ggcgccgagg ccccccgcga gccagcgccg 200

 cggggctggc ggccaaggtt ggggagatga tcaacgtttc cgtgtccggg 250

 ccctccctgc tggcggccca cggtgccccg gacgctgacc ccgcgcccag 300

 gggccgcagt gctgcgatga gcggccccga gcccggcagc ccctacccca 350

 acacctggca tcatcgcctg ttgcagagga gcctcgtgct cttctcggtt 400

 ggggtggtcc tagccctggt gctcaacctg ctgcagatcc agaggaatgt 450

 cactctcttc cccgaggagg tgatcgccac catcttttcc tccgcctggt 500

 gggtccctcc ctgctgcggg acagcagctg ctgttgttgg cctactgtac 550

 ccctgtatcg acagtcacct cggagaaccc cacaaattta agagagaatg 600

 ggccagtgtc atgcgctgca tagcagtttt tgttggcatt aaccacgcca 650

 gtgctaaatt ggattttgcc aataatgtcc agctgtcctt gactttagca 700

 gccctatctt tgggcctttg gtggacattt gatcgttcca gaagtggcct 750

 tgggctgggg atcaccatag cttttctagc tacgctgatc acgcagtttc 800

 tcgtgtataa tggtgtctat cagtatacat ccccagattt cctctatatt 850

 cgttcttggc tcccttgtat atttttctca ggaggcgtca cggtggggaa 900

 cataggacga cagttagcta tgggtgttcc tgaaaagccc catagtgatt 950

 gagtcttcaa aaccaccgat tctgagagca aggaagattt tggaagaaaa 1000

 tctgactgtg gattatgaca aagattatct tttttcttaa gtaatctatt 1050

 tagatcgggc tgactgtaca aatgactcct ggaaaaaact cttcacctag 1100

 tctagaatag ggaggtggag aatgatgact taccctgaag tcttcccttg 1150

 actgcccgca ctggcgcctg tctgtgccct ggagcattct gcccaggcta 1200

 cgtgggttca ggcaggtggc agcttcccaa gtattcgatt tcattcatgt 1250

 gattaaaaca agttgccata tttcaaagcc ttgaactaag actcaattac 1300

 caacccgcag ttttgtgtca gtgcccaaag gaggtaggtt gatggtgctt 1350

 aacaaacatg aagtatggtg taataggaat aatatttatc caaaagattt 1400

 ttaaaaatag ggctgtgttt aaaaaaaaaa acaaaacaag aaaagcagca 1450

 gtgattatag agaggtcaca ctctaagtgg ggtcgcggcg tggccacgct 1500

 tcacggtcac gctcgtccgt cctgcagtgg cgtgtttaca tggtcacacg 1550

 tgtgtgtatc accagtgggt caactgcttg tcattcctcc cgtggcagtt 1600

 tgtgtagaca atcttactga gcaaaaggca atgaaaagtc ttggttccca 1650

 cactgcgata tattggaatt ttcacctcag tttatgaagt ttatttcgaa 1700

 atccatagtc atctaagaat gaatacctgt ctgccatgta tttcaatctt 1750

 agtgagccaa aattgtttgt ttgttactac agaatagaga tgactgtttt 1800

 ttgccacagc cctatggaat ttgcaatctg tgattgcctt gtaaaaagga 1850

 gagtgcatat ggcactgcat taaacgtgtg gtgtttctag tcaatgatat 1900

 tggtgagcac aatgtattca tttaatggca tagaccatac cagacctaat 1950

 ttgcaagtat tgggtcttaa acttcaagtg caatgtatat gaaaaccaat 2000

 ctgagccttg tatctcttaa atatttattt tttttaacgt gtgagatgtt 2050

 cgagagaagg ttctccattc atttcagtgc tgcctggagg aaactcggca 2100

 atgatttctt tcagttgtga agttcctttc gtgttacacc ctccactgaa 2150

 ccctcaacct tcgaaatact ccagttttgt gggtttggtc atttttactt 2200

 ataaatttac ctttttgtat tttgcaattt acatgtgttt ggtttgtttt 2250

 aaattctgtg aaagtggctt gattaaaaga ctccttttaa atggaagcca 2300

 ccagtcagca gaatggaagc ttagaggaac ttgcctgtga gcgctggtct 2350

 ttgtgtttgg ttttgtgatg taacgatctt tgctggggtt ttttgctttg 2400

 ttttgaggga aatgtcttgg agtaaatttt aagttcctgg agttaatttg 2450

 ttttacagga attttgtttt ttaaaaaaat aggatcattc tgaactttgg 2500

 aatgaccccc ttatatattt tctgaaaatg aaaacagtta catgaaaaaa 2550

 atttccaatg aagatgtcag cattttatga aaaaccagaa gttattagat 2600

 gaaagcagcg agtgaatctt taaaacagac ttgatcacgc acacacaata 2650

 agtctttctc tccgaaaccg gaagtaaatc tatatctgtt agaaataatg 2700

 tagccaaaag aatgtaaatt tgaggatttt tttgccaata gtttatagaa 2750

 aatatatgaa ccaaagtgat ttgagtttgt aaaaatgtaa aatagtatga 2800

 acaaaatttg cactctacca gatttgaaca tctagtgagg ttcacattca 2850

 tactaagttt tcaacattgt gttctttttg cattcatttt ttacttttat 2900

 taaaggttca aaccaaaaaa atctatgtcg gtgcggagaa agaggtaatg 2950

 aaatgccagg aattcggata tcaagct 2977

<210> 409
<211> 241
<212> PRT
<213> Homo sapien

<400> 409
 Met Ile Asn Val Ser Val Ser Gly Pro Ser Leu Leu Ala Ala His
   1               5                  10                  15

 Gly Ala Pro Asp Ala Asp Pro Ala Pro Arg Gly Arg Ser Ala Ala
                  20                  25                  30

 Met Ser Gly Pro Glu Pro Gly Ser Pro Tyr Pro Asn Thr Trp His
                  35                  40                  45

 His Arg Leu Leu Gln Arg Ser Leu Val Leu Phe Ser Val Gly Val
                  50                  55                  60

 Val Leu Ala Leu Val Leu Asn Leu Leu Gln Ile Gln Arg Asn Val
                  65                  70                  75

 Thr Leu Phe Pro Glu Glu Val Ile Ala Thr Ile Phe Ser Ser Ala
                  80                  85                  90

 Trp Trp Val Pro Pro Cys Cys Gly Thr Ala Ala Ala Val Val Gly
                  95                 100                 105

 Leu Leu Tyr Pro Cys Ile Asp Ser His Leu Gly Glu Pro His Lys
                 110                 115                 120

 Phe Lys Arg Glu Trp Ala Ser Val Met Arg Cys Ile Ala Val Phe
                 125                 130                 135

 Val Gly Ile Asn His Ala Ser Ala Lys Leu Asp Phe Ala Asn Asn
                 140                 145                 150

 Val Gln Leu Ser Leu Thr Leu Ala Ala Leu Ser Leu Gly Leu Trp
                 155                 160                 165

 Trp Thr Phe Asp Arg Ser Arg Ser Gly Leu Gly Leu Gly Ile Thr
                 170                 175                 180

 Ile Ala Phe Leu Ala Thr Leu Ile Thr Gln Phe Leu Val Tyr Asn
                 185                 190                 195

 Gly Val Tyr Gln Tyr Thr Ser Pro Asp Phe Leu Tyr Ile Arg Ser
                 200                 205                 210

 Trp Leu Pro Cys Ile Phe Phe Ser Gly Gly Val Thr Val Gly Asn
                 215                 220                 225

 Ile Gly Arg Gln Leu Ala Met Gly Val Pro Glu Lys Pro His Ser
                 230                 235                 240

 Asp


<210> 410
<211> 12003
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 7240
<223> Unknown base

<400> 410
 agctcacagt ggggtcgagg agacacagca caggcttctg aaaggtgccc 50

 tgtccattag ggagcacccc atttacagat gggtcatcct tcagctcact 100

 agtttcccag cgcatgacag tgggtagctt ttttttttcc tattataaac 150

 aaatcttcga tgtgactgcg atgatctacg gatgatctac gtatctggtt 200

 gtgtgatcct caagcactta tgcaaggtgg agtgtaaaca atggccaaga 250

 cccaaactgc aatgttccct gaagtccaac ctgcttggag tccttgggaa 300

 cgtgtacaat ggttaacagg cttgagagga gtcagctggg agagtgagag 350

 cgagactgcc ctgcagaggg gccgctgagg atggacccct gtaggccgtc 400

 cacacccacc acgcgtgtca tcctcaggaa atgcaaccgg atgctcggaa 450

 tttcgcccct aaagcgactc agggcagtct cagctcagga agacttcttt 500

 ttttgacctt ctggcttaaa gccacaaccc caggctgagg atgccacatc 550

 aacggcgttt cctcgccacg ctgcaggcgt gactcacgtt tctaagcctg 600

 cagggtcccc gggccaagcg cggctactga gagcacagcg tcctccctca 650

 gcccctgctc atctgcacgg agcaaagccg cagctttctc tgctgtcagc 700

 gctttatacg actcggatgt aggctctgag cgggcacggg cccgccctca 750

 gacggcgacc cgaggggcaa acaggatgga ggcgcgctcc cttggaggct 800

 gtggtctcga ttttatctgc tcctgggtgg tgcgggtggt ttgctctcta 850

 ggcgtgagca aaggccacaa ggggcccgaa aaaatcaccc aaggatgcaa 900

 gcccgccatt gcgctgagca ggggcctccc cgccgccaga gcccgcgccc 950

 ctccagggag gcccgcgcga tcgagacccg ccgcctcccg accaggcgcg 1000

 ggacaccagg cgaggggaga caggagccgg gaggggaggg gccgggcccg 1050

 caaccccacc cagtcctgcc tccgcctcct cccggtagga ccgtcccctc 1100

 ccaggcccca gctccgcggc cgcctcacca gaccgcgtgc ggacgggctc 1150

 gcgggcgggg cggggcaagc tcaggccacg cccctgggcg gtgcgcgcgg 1200

 gcggtgggta ggccgggcag gctcacgtga tgcgggcccc gcggcccgcg 1250

 gatataaacc cgcgcgcccg ccaggcgctg cggccgtccc gggccgtgac 1300

 tcctcctttc ccccgccccg cctccgttcg gagagccggc gggcgggcgc 1350

 ctctcggcca ggtacgcggc cggctgggat aggggtcgcg ggcgggcttt 1400

 ggtcgcgcag cagccggtcc tccccggagg taggcgggcg cgggccctgt 1450

 tgggtctttg ggacgcgggt cccgctgggg ccggggatgc tcctctctgt 1500

 gagcgcggtc ccgtcccccc ctgtccccgg gcgggcgcac gggggtctaa 1550

 ccttgggggg cggcgctccc gcctgtcccg ggtgccgggg ttcgcgtccc 1600

 gcggggcctt cctcgctctt tgtctcttct gagtgaactt gatgaccccc 1650

 ttcttccagg aagcgcctct tggacgcgtg tgaccgatgc ccagattgca 1700

 cgaccacttc tggagctgct cctgtgcgca cagcgcgagg cgccgaggcc 1750

 ccccgcgagc cagcaccgcg gggctgccgc ccaaggttgg ggagatgatc 1800

 aacgtttccg tgtccgggcc ctccctgctg gcggcccacg gtgccccgga 1850

 cgctgacccc gcgcccaggg gccgcagtgc tgcgatgagc ggccccgagc 1900

 ccggcagccc ctaccccaac acctggcatc atcgcctgtt gcagaggagc 1950

 ctcgtgctct tctcggttgg ggtggtccta accctggtgc tcaacctgct 2000

 gcagatccag aggaatgtca ctctcttccc cgaggaggtg atcgccacca 2050

 tcttttcctc cgcctggtgg gtccctccct gctgcgggac agcagctggt 2100

 gagtacccct cctggttctt ctggaagtaa aaagggtgtc ttttcggttg 2150

 aaagtacttt tcagcctata agaaacatgc atttgaaact ggaactatcc 2200

 acagattgaa agtgtgcatc tccagtcttg ggatttagag aaatgaagga 2250

 ggggtagaga ggacctggca cccccgaggg cgggttcggg acacagctct 2300

 ctgaagtttg aggaagcaca gtgatggaga tgaggcaggg agataattgg 2350

 ctgttcaagc aggtgctgtg ccaagttgac tgagggccct tccctcctgg 2400

 cgtccgggta cagccccagc tgtcatcccg cgccagccgc cccggattgg 2450

 ccgcctgggg aactggtgag cagcgggact gaaaggccat tggtcgcggc 2500

 agcaaacatg ctaccctgct ggataactga aaacaaaccc gtcacatggg 2550

 ttcaggaggc ggttgccagg ggagcaactt ctcagcactt ccttttgccg 2600

 ggtcgctgag taaactgtgg tctgaagcca aaccgcctac accctgaact 2650

 gttagagctc tgtagattac gttcttaaga aaagataccc cttacggcgt 2700

 ttagattttc gtacacccaa gcagtagcat agatgctgta caacgtaaca 2750

 ctgagtcagt ctgaactgtg gacacgggga ctgctgggtg tgtgtactag 2800

 actttcttgg ctatcattga cccgctttta tagaaatgtt gagttgatct 2850

 tggctcagca gatcacttac tgctcctgta gtcacacagc atttgtttat 2900

 ttaacgagct tgtcgggtgc tttctgcaac ctcaactcta taagctgttg 2950

 aaatgttaat ccaaaagtga gcaccacaag cccctatcct taagcagctt 3000

 agagtctggt ggggaaaaca aaccagtatg tcagtgactc cagtgcaggg 3050

 cagggagcat cctgtttgct ttgtggctga cgcctgccag ctgactgctg 3100

 accataggct tcagatgctt tgctgtgttc attccttaca gcaatgccat 3150

 ttgtagcttc atttatagat gtggcaactg aatcacagtt gaagtcaagc 3200

 ccaaggttgg cgcaggtaga aagggcccaa gccatcggtg gtagactgct 3250

 ccttcttgcc atggtagggt gtgtctcctg cactgtggaa acacattgcc 3300

 tcagttgact cactgaaaac agcaagcagc agagaggttt gtagcagatt 3350

 aaacaggggg ctccgtgttg aagaactagg acaggtgtct gtaactaaaa 3400

 agtagtgggt agaatgtttt catatgtgtt ctcggaggga cgggttcctc 3450

 tgtcgtttgt cgaaacacat tatgtggctg ttctaagtga acactttttg 3500

 agaacgatat ctagagttga aattccatgt ttcatataca gttggcagaa 3550

 tagtttcttt cctttaaccc taaaacttga tcttagaaat gagataggta 3600

 gccttcagta gttgtaattg gatcctcaag ggtttctagg aatatctgga 3650

 caatttctca tactctcata ttctactttt ttttaaacca tcagccaaga 3700

 gcataagtaa aatttttcat agtatgtttt ttacctattt atttattaag 3750

 ctatagtgag gtaaagttaa tttggggggt ccatttttca gaactccaaa 3800

 attagaacct gatgaagtat aataaattga aaacaacatt ttttatctga 3850

 atgtttgatg caaactgtgt ttcttgtttc tcagttgaac ctaaaaggta 3900

 tatttctttc atactagact gaggtgaaac aattgcaggg ttctcaagag 3950

 ccctgggaca cagtgaccct tgtgtcccag catccaaccc cacggggcgg 4000

 caccccactc ccccctacag acattcattc ctgccttcat ctttggcatt 4050

 ttacttctct tgggggaatg ccattccttc ccacctgtcc aaattccaag 4100

 ttcgtgtcta taaagaataa ctattccaga ccacagtgat ctctttctct 4150

 gtgtcccagt tacataatcc ttataatttt acacatgaga aaacaaacat 4200

 gcagagccac gtcccatcag agggcaagct gggatttgag gctgagtttt 4250

 ctcttcttgg tctggtgttc tttccgcagc ttgaggcttg accatgcggg 4300

 aaccagatgg agaataagcg aagcctgtgt ggggctgtct cgccccgtac 4350

 ttgcccatgt gcatgtgtgc acagtaggtg ctcagtgcct cgtacagaac 4400

 atgctagaac ccccgaaaat caactccagg gtcactctag gagcatgtga 4450

 cccagactgt caaagtcaca tcagcaaata tgtatctcat cacgtgcccc 4500

 aggcccagta ctgggtggtg gggaggagtg tcaagagctg tgatgtgaca 4550

 gggggtggac agatgctaac ctttttattg taagatagaa atcacaccgg 4600

 atgaaaagac aaggtggaac tacatagtca tttaagttct gtgtgcttta 4650

 ggcaaatgtg gatattaaat ataaggttac aatattgctc atattaatat 4700

 gaataatccc tgcttgattc cttcctgtgt ttactgagac atgttcaact 4750

 acactaaata atagtgattt ttaaaaaact tttcccaaac agtacaattt 4800

 tgtgggagtg gtactcaaag agaacaagaa tataaaatca ctctgaagtt 4850

 atagctgata attttttcta ggaaaaggac tggtttgagt aatgtactgt 4900

 gttactaatg accacgttgg aaattctgga acttggaatc tgctgtattc 4950

 taacattggc aacttttttt aaaacagctg ttgttggcct actgtacccc 5000

 tgtatcgaca gtcacctcgg agaaccccac aaatttaaga gagaatgggc 5050

 cagtgtcatg cgctgcatag caggttttgg tggcattaac cacgccagtg 5100

 ctgtatcctt aattttctgt gctacgtcca gagtatcttc ttaggttata 5150

 tattgaagca ttttgttttg ttatatactc aaatgactcc atgtcataat 5200

 acagacatga tggtggtacc tacccatttc agattactaa aaagagaaag 5250

 aagaatgggg ctatcgatga cttcatagca aaatatattg ttttatggtc 5300

 aaaataaata taaaattatt taaattttta tatatattaa aaaaattttt 5350

 aaaaatatat ataaaatata taataaatat atatttatat aaatatatat 5400

 aagcactcca tatatagctt tcagcaagtt cattctcatg gctaagtttc 5450

 tgactcagcg atggcaggga gatttcaggt gatcttaatg attactgtaa 5500

 cctgcatcca acaaatcctt tctttagctc attacacagg ctttatggac 5550

 agtgaattat ctgtgggaca ataataaaat acccatgttt ttaacccttg 5600

 tggttttacg tttttttatc ttaataagag tcaccgaact tttccttaac 5650

 ttttatatca ccagaaattg gattttgcca ataatgtcca gctgtccttg 5700

 actttagcag ccctatcttt gggcctttgg tggacatttg atcgttccag 5750

 aagtggcctt gggctgggga tcaccatagc ttttctagct acgctgatca 5800

 cgcagtttct cgtgtataat ggtgtctatc agtatacagt aagtgtgtgt 5850

 tttcaaatat tggctttgga aagcttagat attttcatat tttatttgtt 5900

 ttttatatag aatgatacag atttaggcat gaaattctca aaaatgctgc 5950

 tatccataac ttaatgtaac gcaaaggaaa accaagtagt agcagttaca 6000

 accaaacaaa tatgaacatt cgtaacattg gatggttgat atgcgttctg 6050

 catatcccca ctacagagaa tctgtgatgt agaattgagc caggtgaaat 6100

 tgactgctaa ggtacagttt cttttctcgc tccaggtata cgtccccaga 6150

 tttcctctat attcgttctt ggctcccttg tatatttttc tcaggaggcg 6200

 tcacggtggg gaacatagga cgacagttag ctatggtaag tgaaatgatc 6250

 atattatctt ctaaaacttg cttctcttta ccttgataga atgactttac 6300

 atgatacatt caaatttgcg ttcatatatt ctggttcaga cttgagtgac 6350

 aactactgag aaaagcttgg agtccggatc aagcaacctc ccgcttcagc 6400

 gtcccgagta gctgggatta caggcacatg ccaccatacc cggctaactt 6450

 ttttgctttt tgtggagatg ttatctccct gccttgtcca ggccgggctc 6500

 gaactcgtgg gctcaagcca tcctcccacc ttggcctccc aaagcactgg 6550

 gattataggc gtgagcctgg ccttgctttt tttaatatta aaaatctggt 6600

 cggatggtcc cacatggaaa tagtatgttg ttttcatgca ttcgccatca 6650

 tccccgttaa tagtcttccc aaaggagagc tggcaacctc catcattgct 6700

 ttcttgcttt gagatttttg tttcgggaac tctctttggg agagaattcc 6750

 ctaagaaggt ttttaaagaa taaaattgtc ctcaaccaga ttgactaatt 6800

 acacattata actacaactt gaataacatt taaagagttg ggttatttct 6850

 tgtttgatag gttggatgct tgttatatgt caagcctttt taaatcggtt 6900

 ttaagaaata agcattattt tggtggaggt agaaatttca caacattcat 6950

 aagttctaaa catctagaaa tggttggagg aaacattttc gttttgaaga 7000

 tagtttcatt aagtaatccc tgctgtgctc ctttgcttac agaaaaaaat 7050

 gttaaagata actccccata ggatagttgg tgtaattata attctcctta 7100

 cttcagcttt ctcttcatcc tttttattct ttaagcttgg gggaaaatgt 7150

 ttggatgttc tcgtatctta aaactggagg agagaggctg ggcgcggtgg 7200

 ctcacgcctt taatcccagc actttgggag ctgaggcggn cggatcacga 7250

 ggtcaggaga tcgagaccat cctggctaac acagtgaaac cccgtctgtc 7300

 ctgaaaatcc ccgaaaggaa aaaaaaaata cccaggcgtg gtggtgggca 7350

 cctgtagtcc cagctgcttg ggatgctgag gcaggagaat ggcgtgaacc 7400

 cgggaggcag agcttgcaat gagccgagat tgtcccactg cattccagcc 7450

 tgggtgacag agcaagactc tgtcgccgaa aaaaaaaaaa aaactggaga 7500

 agagagatca ccaccttaat ccccttccct actgggctat cacatgaaac 7550

 tgagctctga ggttctaagc ctaacccgcc taccactgtt tttattcata 7600

 aatacttaaa tccttacctc tggatcccaa ctgttactct ttttttcact 7650

 tcaaaatttg caaactcatt tctatccatc aaaccccgga aatggcccag 7700

 gggcttcaca gtgcagtccc ctccctcctg ctgcatccgt tcctcaggct 7750

 gtgccccagg ttgcattcgt ggtgcgtgtt ttctcccagg gcagccttcc 7800

 ccacattcca ctcttgtcat actgttgact cacaaaatgg aagtggctga 7850

 atgttccagg gatagtgtct aagagctatt ggtttaaggt tgaaacctac 7900

 accaagtaag gctttgtgaa gggagatgac gagagtgaag ttgttgacag 7950

 tctgaaggtg aagagattcc gagggtcagt tcagcaccgg gaccagaccc 8000

 gcccagatcc agggtaattt gaggtctgtg tttgggtgct gatggttttg 8050

 gccagtggac tccacaacct ctccttctta gctgtctcag gtctcttcag 8100

 atgccttggg tcttaactta tgcttccctc ccttaagaag aaacatagtt 8150

 aattggcaag aataaccatg ctcaaaaagt tacaagttgg gtttgggttc 8200

 aagttatatg ggcttcctag cttttctatg tggtatttcc ccccacacat 8250

 gccgttgtcc tttgtgtccg aaaatacagc agaaacattt gttatcagcc 8300

 tgttacggtt tttttgtttg cttgtggttt gtttttattt gtactttttt 8350

 ggagacggag tcttgctttg tcacccagac taaagtgcag tgggacaatc 8400

 ttggctcact gcatttgaac cgtctcccag gttcaaatga ttatcctgcc 8450

 tcagcctccc aagtagctag ggatcacagg gcgcccacca ccgcacctgg 8500

 ctaatttttc tgtttttagt agagacgggg tttcgccacg ttggccaggc 8550

 tggtctcgaa ctcctgacct caggtgatcc acctgcctct gcctcccaaa 8600

 gtgctgggat tacaggaatg agacaccgcg cccggcccag tctgtatgtt 8650

 taaaaaggaa aatgagtctg taaccatcat ttattagaac ttgtagtatg 8700

 ttgctgtgtg tagcttcaag tccttcctca agagtaagct gcaaactgcc 8750

 aacagaaatc aagcctgtcc tgttgacact gcccggcccc actgggacac 8800

 ctggagggag agtccccccc acctcagtgt cagattggaa tttgatttgg 8850

 cggtcctgtt tgtgattgac ccaatacagc tgctaatgat aataatacta 8900

 ttattgttat tgagggttta catttgttgg gctcttactg ctgcacagga 8950

 ggcattgtgc tgagcgtttc cattgttagg cagtttagtc ctcatacaca 9000

 agtctttgga gtagaaacta ttattagccc atttctaaaa ggggaattag 9050

 cagcttagga agattaaaca gcttgaccag gtgggtggca gaggtcgacg 9100

 ttgcaagccg acttctcatt agcataccac actgccaata ccaacacaat 9150

 gctcgcactg tctcacctgg aagcaggtta cagcagcctg cgttggtgtc 9200

 tgggttgcca tttacaatgt gccaccatta ggcaacactg ctggaagtcc 9250

 ctgtgccacg tgtcaggtcc gccccggcct ggctgtcgcc cgcctctggc 9300

 gtctctgcca ggcctcactg gggtctctgt cgaccaggga ttctaaaagt 9350

 ccacttccca tctatttatt cagtacatta gggaacaggg agtcaaattt 9400

 ttgttggccc aagtttcctt tcccgggttt gcttgcccaa gaagtttgcc 9450

 cgttttttgt tttccccccc cccacggttt gaataagaac cccctcccca 9500

 gttgtgcaaa aacccaagaa acttgggcag ttccttttca cctttgttcc 9550

 aattcccttg aaagcattgt attgtttccc taaggaagtc cttaattgtg 9600

 ttttgtcccc caggggtagt accctggcaa taccctggtt gactccaacc 9650

 cagactcatg actttcttac ctgccctggt tttgttcaag atgagaggct 9700

 cttttggcct gttttctgga tgagtaatct ccgtcattgc tgaagtgagg 9750

 agctcagctc cttcctctta aagtgagtgg agggcaatta agtaacgtgg 9800

 gaagtcacga ttctgaggga aaaaaattct gtatggagtt tctcttttgc 9850

 cctttagcag aagctccgtg acctcaggaa ggtcatttaa tctctctgtc 9900

 tttgcttctt catcagtgaa atactgttct ccattaagaa tttaccctga 9950

 ggtgcctggt catagtagta actgtagtgt ctacctctca gaagctctgt 10000

 gagggtcaga tgaggaagaa catgtagaaa ggatttccca actgtgaagc 10050

 tctgtgtgaa ttgagggcac acagagcttc agtattacaa agcatgacct 10100

 atttccaatg tctgtttcaa caaactgctg gtaaggtggg ttataacaca 10150

 ggcatcagat actaataaag gtttgtggca gaaacctccc ttcagataaa 10200

 ggttcaatcc cttaaattgc agttagaact ttcaggaacc tatcataccc 10250

 taagcatcac catgctttga taaaattggg tgtttccttt atatagatat 10300

 taatttagtt aaactttcac caagtcttac acttacatgg tggctttaat 10350

 aagggcctca gcagcgtaat ttcacctgag gcagagaatt atcctaattt 10400

 tgcaggtgag agctgtggct cacggggcca gagccatgaa gacggcgcag 10450

 gggagctggg agagctggcc tcggtctcca gttctctgca catgtcccac 10500

 ctctcaatct tgttgcttca gtcaaagaaa gtgtcaatat ttcccatgtt 10550

 aggacctact taattggtaa ttaaaatatt tatacattta gtgctaattt 10600

 tctctttcct tttttttttc ctttctacac atagggtgtt cctgaaaagc 10650

 cccatagtga ttgagtcttc aaaaccaccg attctgagag caaggaagat 10700

 tttggaagaa aatctgactg tggattatga caaagattat cttttttctt 10750

 aagtaatcta tttagatcgg gctgactgta caaatgactc ctggaaaaaa 10800

 ctcgtcacct atctagaaaa gtcaagaata gggaggtgga gaatgatgac 10850

 ttaccctgaa gtcttccctt gctacccaca ctggcgcctg tctgtgccct 10900

 ggagcattct gcccagccta cgtgggttca gtcaggtgcc accttcccaa 10950

 gtattcgatt tcattcatgt gattaaaaca agttgccata tttcaaagcc 11000

 ttgagctaag actcaattac caacccgcag ttttgtgtca gtgcccaaag 11050

 gagggaggtt gatggtgctt aacaaacatg aagtatggtg taataggaat 11100

 aatatttatc caaaagattt ttaaaaatag ggctgtgttt aaagaaggaa 11150

 tcaaaacaag aaaagcagca gtgattatag agaggtcaca ctctaagtgg 11200

 ggtcgcggcg tggccacgct tcacggtcac gctcgtccgt cctgcagtgg 11250

 cgtgtttaca tggtcacacg tgtgtgtatc accagtgggt caactgcttg 11300

 tcattcctcc cgcggcagtg ttgtgtagac aatcttactg agcaaaaggc 11350

 aatgaaaagt cttgggctcc cacactgcga tatattggaa ttcccacctc 11400

 agtttatgaa gtttatttcg aaatccatag tcatctaaga atgaatacct 11450

 gtctgccatg tatttcaatc ttagtgagcc aaaattgttt gtttgttact 11500

 acagaataga gatgactgtt ttttggcaca gccctatgga atttgcaatc 11550

 tgtgattgcc ttgtaaaaag gagagtgcat atggcactgc attaaacgtg 11600

 tggtgtttct agtcaatgat attggtgagc acaatgtatt catttaatgg 11650

 catagaccat accagaccta atttgcaagt attgggtctt caaacttcaa 11700

 gtgcaatgta ttatgaaaac caatctgagc cttgtatctc ttaaatattt 11750

 attccttcta acgtgtgaga tgtcccgaga gaagggttct ccattcattt 11800

 cagtgctgcc tggaggaaac tcggcaatga tttcttcagt tgtgaagttc 11850

 ctttcgggtt acaacctcca ctggaaccct caaccttcga aatactccag 11900

 ttttgggggt tggggccatt tacttataaa tttaccgccg ggtttttgga 11950

 atctacatgt cttgggggcg ggctcaaatt cttcgaaagt ggttggatta 12000

 aaa 12003

<210> 411
<211> 1549
<212> DNA
<213> Homo sapien

<400> 411
 tggcagtgcg cctgcgccgc gtcggcgtgc ggaacgccgc ggtgtctcgg 50

 cgcctctgcg cgcgggaaga tggcggaaca ggctaccaag tccgtgctgt 100

 ttgtgtgtct gggtaacatt tgtcgatcac ccattgcaga agcagttttc 150

 aggaaacttg taaccgatca aaacatctca gagaattgga gggtagacag 200

 cgcggcaact tccgggtatg agatagggaa cccccctgac taccgagggc 250

 agagctgcat gaagaggcac ggcattccca tgagccacgt tgcccggcag 300

 attaccaaag aagattttgc cacatttgat tatatactat gtatggatga 350

 aagcaatctg agagatttga atagaaaaag taatcaagtt aaaacctgca 400

 aagctaaaat tgaactactt gggagctatg atccacaaaa acaacttatt 450

 attgaagatc cctattatgg gaatgactct gactttgaga cggtgtacca 500

 gcagtgtgtc aggtgctgca gagcgttctt ggagaaggcc cactgaggca 550

 ggttcgtgcc ctgctgcggc cagcctgact agaccccacc ctgaggtcct 600

 gcatttctca gtcggtgtgt aatcacgttc cagggcccaa agcccagctc 650

 tttgttcagt tgacttactg tttcttacct taaaaagtaa ttgtagatgg 700

 aaatcagttg tgtttggcag gagaatcaat aaaaatcttt gattcagaca 750

 gcttatgggg tattttaagc attcttagac tagttgaaca tctcactttg 800

 ccccagttac aaaaatagta gaacaagcaa cataaaacaa tgaaggaaaa 850

 cctcacttga aggcccaggt caacatctaa gcctgttgag acttagataa 900

 tcgagtctac ctcttcagta ggtttgtgtg gatggcctgg agggcaggtg 950

 ccctctgctc cccagtgcta cctctctctt ccctagggcc ttttgtggat 1000

 tgacagtagt cccctccgta ggagctcaca gtctagatta gaagtgtttt 1050

 aatttctaca cacccatagt gcacacttgt atattgaaaa gatagggaag 1100

 agagaaacat ttatggaatc agtcgttggc accttcaata cttcatgatt 1150

 tttgtcgagt ttacttcatg aggaggtcag cccattggct cccatctgaa 1200

 ccactttgcc tctgaaactt aattacatcc agaaagaagg acacttgtat 1250

 gctagtctat ggtcagttga ggaatatgac tgtttttata tgcacatgta 1300

 acccaaatgt ccaatataaa ttggcttatt ttttaaaata attttaaaag 1350

 ttgggaaaag tgttattatt tggcatgctt aaatattgaa taagtattct 1400

 tcatcagcat ttaataaatg tataggcaga tgtaaggtaa tttctgtgta 1450

 ttttgagata atgtcaaaat catgaatatt tcaaaataaa ctggggagtt 1500

 ataaaaatac aactagagat ataaaaaaaa aaaaaaaaaa aaaaaaaaa 1549

<210> 412
<211> 158
<212> PRT
<213> Homo sapien

<400> 412
 Met Ala Glu Gln Ala Thr Lys Ser Val Leu Phe Val Cys Leu Gly
   1               5                  10                  15

 Asn Ile Cys Arg Ser Pro Ile Ala Glu Ala Val Phe Arg Lys Leu
                  20                  25                  30

 Val Thr Asp Gln Asn Ile Ser Glu Asn Trp Arg Val Asp Ser Ala
                  35                  40                  45

 Ala Thr Ser Gly Tyr Glu Ile Gly Asn Pro Pro Asp Tyr Arg Gly
                  50                  55                  60

 Gln Ser Cys Met Lys Arg His Gly Ile Pro Met Ser His Val Ala
                  65                  70                  75

 Arg Gln Ile Thr Lys Glu Asp Phe Ala Thr Phe Asp Tyr Ile Leu
                  80                  85                  90

 Cys Met Asp Glu Ser Asn Leu Arg Asp Leu Asn Arg Lys Ser Asn
                  95                 100                 105

 Gln Val Lys Thr Cys Lys Ala Lys Ile Glu Leu Leu Gly Ser Tyr
                 110                 115                 120

 Asp Pro Gln Lys Gln Leu Ile Ile Glu Asp Pro Tyr Tyr Gly Asn
                 125                 130                 135

 Asp Ser Asp Phe Glu Thr Val Tyr Gln Gln Cys Val Arg Cys Cys
                 140                 145                 150

 Arg Ala Phe Leu Glu Lys Ala His
                 155

<210> 413
<211> 1345
<212> DNA
<213> Homo sapien

<400> 413
 acttggcctt acactccgct cggctcacca tgtgtcactc tcgcagctgc 50

 cacccgacca tgaccatcct gcaggccccg accccggccc cctccaccat 100

 cccgggaccc cggcggggct ccggtcctga gatcttcacc ttcgaccctc 150

 tcccggagcc cgcagcggcc cctgccgggc gccccagcgc ctctcgcggg 200

 caccgaaagc gcagccgcag ggtctctcta ccctcgagtg gtgagtatcg 250

 ccgaagtggg cattcgcggt gtgcgctgcc ctggagtcac tggggaacga 300

 cccgactcca gagcctcgac ctgacctgtc tcctgttttg tctcccctta 350

 gtccggcgcc agctgccagt cgaggaaccg aacccagcca aaaggcttct 400

 ctttctgctg ctcaccatcg tcttctgcca gatcctgatg gctgaagagg 450

 gtgtgccggc gcccctgcct ccagaggacg cccctaacgc cgcatccctg 500

 gcgcccaccc ctgtgtcccc cgtcctcgag ccctttaatc tgacttcgga 550

 gccctcggac tacgctctgg acctcagcac tttcctccag caacacccgg 600

 ccgccttcta actgtgactc cccgcactcc ccaaaaagaa tccgaaaaac 650

 cacaaagaaa caccaggcgt acctggtgcg cgagagcgta tccccaactg 700

 ggacttccga ggcaacttga actcagaaca ctacagcgga gacgccaccc 750

 ggtgcttgag gcgggaccga ggcgcacaga gaccgaggcg catagagacc 800

 gaggcacagc ccagctgggc taggccggtg ggaaggagag cgtcgttaat 850

 ttatttctta ttgctcctaa ttaatattta tatgtattta tgtacgtcct 900

 cctaggtgat ggagatgtgt acgtaatatt tattttaact tatgcaaggg 950

 tgtgagatgt tccctctgct gtaaatgcag gtctcttggt atttattgag 1000

 ctttgtggga ctggtggaag caggacacct ggaactgcgg caaagtagga 1050

 gaagaaatgg ggaggactcg ggtgggggag gacgtcccgg ctgggatgaa 1100

 gtctggtggt gggtcgtaag tttaggaggt gactgcatcc tccagcatct 1150

 caactccgtc tgtctactgt gtgagacttc ggcggaccat taggaatgag 1200

 atccgtgaga tccttccatc ttcttgaagt cgcctttagg gtggctgcga 1250

 ggtagagggt tgggggttgg tgggctgtca cggagcgact gtcgagatcg 1300

 cctagtatgt tctgtgaaca caaataaaat tgatttactg tctgc 1345

<210> 414
<211> 193
<212> PRT
<213> Homo sapien

<400> 414
 Met Cys His Ser Arg Ser Cys His Pro Thr Met Thr Ile Leu Gln
   1               5                  10                  15

 Ala Pro Thr Pro Ala Pro Ser Thr Ile Pro Gly Pro Arg Arg Gly
                  20                  25                  30

 Ser Gly Pro Glu Ile Phe Thr Phe Asp Pro Leu Pro Glu Pro Ala
                  35                  40                  45

 Ala Ala Pro Ala Gly Arg Pro Ser Ala Ser Arg Gly His Arg Lys
                  50                  55                  60

 Arg Ser Arg Arg Val Ser Leu Pro Ser Ser Gly Glu Tyr Arg Arg
                  65                  70                  75

 Ser Gly His Ser Arg Cys Ala Leu Pro Trp Ser His Trp Gly Thr
                  80                  85                  90

 Thr Arg Leu Gln Ser Leu Asp Leu Thr Cys Leu Leu Phe Cys Leu
                  95                 100                 105

 Pro Leu Val Arg Arg Gln Leu Pro Val Glu Glu Pro Asn Pro Ala
                 110                 115                 120

 Lys Arg Leu Leu Phe Leu Leu Leu Thr Ile Val Phe Cys Gln Ile
                 125                 130                 135

 Leu Met Ala Glu Glu Gly Val Pro Ala Pro Leu Pro Pro Glu Asp
                 140                 145                 150

 Ala Pro Asn Ala Ala Ser Leu Ala Pro Thr Pro Val Ser Pro Val
                 155                 160                 165

 Leu Glu Pro Phe Asn Leu Thr Ser Glu Pro Ser Asp Tyr Ala Leu
                 170                 175                 180

 Asp Leu Ser Thr Phe Leu Gln Gln His Pro Ala Ala Phe
                 185                 190

<210> 415
<211> 1810
<212> DNA
<213> Homo sapien

<400> 415
 ctcagttagc ggtggagagg cagtatgtcc ggttcaatgg cgactgcgga 50

 agctagcggc agcgatggga aagggcagga agtcgagacc tcagtcacct 100

 attaccggtt ggaggaggtg gcaaagcgca actccttgaa ggaactgtgg 150

 cttgtgatcc atgggcgagt ctacgatgtc acccgcttcc tcaacgagca 200

 ccctggagga gaagaggttc tgctggaaca agctggtgta gatgcaagtg 250

 aaagctttga agatgtagga cactcttctg atgccagaga aatgctaaag 300

 cagtactaca ttggtgatat ccatccgagt gaccttaaac ctgaaagtgg 350

 tagcaaggac ccttcaaaaa atgatacatg caaaagttgc tgggcatatt 400

 ggattttacc catcataggc gctgttctct taggtttcct gtaccgctac 450

 tacacatcgg aaagcaaatc ctcctgagga ggccttgctg aagttagaaa 500

 gtgcatccac tttggggcga aaactagaga cttgcttggg ggctgcagaa 550

 gtgccctctc ctcgaatcct gccagttgca ttcttccccc ttggagccaa 600

 gacgattggc cagacatcac ctcagatctg agaccagcgt cttccatctc 650

 tcagagcctt actcccaaag tacctgctca ctgttccgtg ttgaacaatt 700

 gccggtgttt cctctcttca ctggtttcca tgagtaccct tatatttcac 750

 aactttctgt tcataagtta tagtgacatt gctctttggt aaaaatgcct 800

 gctttccaat actttgattg catattagac attcttaaca gggcggcagt 850

 ctagtgttga aagttttatt tttccatttt tcttttaagt aaattttttt 900

 taaaaaattc tgatttaggg ctaggtgtgg tggctcaggc ctgtaatcct 950

 ggcactttgg gaggccaagg tgggaacatc gcttgaggcc aagagttcaa 1000

 gaccagcctg ggcaacatag cgagacccct atctgtatta aaaaaaaatc 1050

 tgatttaatt cttttattta tcataagggg tttaattcct gaagtaaagg 1100

 tttgcaccta ttaaacttaa aactgccaaa tgatttttgt tcttttatgt 1150

 gcgtgataaa aatacaaaga atggtgtggc cacctcctcc ctttcaagct 1200

 agggcagcag gtagctcttc ccagcccctg agcccagccc cttcccaagt 1250

 ggtgccggac aaaaaactac atggcccttt cgtgtcttgg gggtggaaag 1300

 ggagggatga attggggtga tagaaccctg gtgaattcag agtaatcttt 1350

 ctttagaaaa ctggtgtttt ctaaagaaac aggataggag tttagagaag 1400

 gcaccaaagc tttcactttg gtttggcacc agtttctaac catctgtttt 1450

 ttctacccta gctatctttt attggtaaaa tataaatgta taattatgtt 1500

 tgtagagctt taccaaggag tttccctcct ttttttgttt gttgattagc 1550

 aaatttttga ttctccattt tccaaaagta agagactcca gcatggcctt 1600

 ctgtttgccc cgcagtaaag taacttccat ataaaatggt atttgaaagt 1650

 gagagttcat gacaacagac cgttttccat ttcatctgta ttttatctcc 1700

 gtgactccaa cttgtgggtt tgttctgttt ttccatgaga ataaaatact 1750

 ggcggttttt tttcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaaaaaaaaa 1810

<210> 416
<211> 146
<212> PRT
<213> Homo sapien

<400> 416
 Met Ala Thr Ala Glu Ala Ser Gly Ser Asp Gly Lys Gly Gln Glu
   1               5                  10                  15

 Val Glu Thr Ser Val Thr Tyr Tyr Arg Leu Glu Glu Val Ala Lys
                  20                  25                  30

 Arg Asn Ser Leu Lys Glu Leu Trp Leu Val Ile His Gly Arg Val
                  35                  40                  45

 Tyr Asp Val Thr Arg Phe Leu Asn Glu His Pro Gly Gly Glu Glu
                  50                  55                  60

 Val Leu Leu Glu Gln Ala Gly Val Asp Ala Ser Glu Ser Phe Glu
                  65                  70                  75

 Asp Val Gly His Ser Ser Asp Ala Arg Glu Met Leu Lys Gln Tyr
                  80                  85                  90

 Tyr Ile Gly Asp Ile His Pro Ser Asp Leu Lys Pro Glu Ser Gly
                  95                 100                 105

 Ser Lys Asp Pro Ser Lys Asn Asp Thr Cys Lys Ser Cys Trp Ala
                 110                 115                 120

 Tyr Trp Ile Leu Pro Ile Ile Gly Ala Val Leu Leu Gly Phe Leu
                 125                 130                 135

 Tyr Arg Tyr Tyr Thr Ser Glu Ser Lys Ser Ser
                 140                 145

<210> 417
<211> 983
<212> DNA
<213> Homo sapien

<400> 417
 gtggaattca tggcatctac ttcgtatgac tattgcagag tgcccatgga 50

 agacggggat aagcgctgta agcttctgct ggggatagga attctggtgc 100

 tcctgatcat cgtgattctg ggggtgccct tgattatctt caccatcaag 150

 gccaacagcg aggcctgccg ggacggcctt cgggcagtga tggagtgtcg 200

 caatgtcacc catctcctgc aacaagagct gaccgaggcc cagaagggct 250

 ttcaggatgt ggaggcccag gccgccacct gcaaccacac tgtgatggcc 300

 ctaatggctt ccctggatgc agagaaggcc caaggacaaa agaaagtgga 350

 ggagcttgag ggagagatca ctacattaaa ccataagctt caggacgcgt 400

 ctgcagaggt ggagcgactg agaagagaaa accaggtctt aagcgtgaga 450

 atcgcggaca agaagtacta ccccagctcc caggactcca gctccgctgc 500

 ggcgccccag ctgctgattg tgctgctggg cctcagcgct ctgctgcagt 550

 gagatcccag gaagctggca catcttggaa ggtccgtcct gctcggcttt 600

 tcgcttgaac attcccttga tctcatcagt tctgagcggg tcatggggca 650

 acacggttag cggggagagc acggggtagc cggagaaggg cctctggagc 700

 aggtctggag gggccatggg gcagtcctgg gtgtggggac acagtcgggt 750

 tgacccaggg ctgtctccct ccagagcctc cctccggaca atgagtcccc 800

 cctcttgtct cccaccctga gattgggcat ggggtgcggt gtggggggca 850

 tgtgctgcct gttgttatgg gttttttttg cggggggggt tgcttttttc 900

 tggggtcttt gagctccaaa aaataaacac ttcctttgag ggagagcaaa 950

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 983

<210> 418
<211> 180
<212> PRT
<213> Homo sapien

<400> 418
 Met Ala Ser Thr Ser Tyr Asp Tyr Cys Arg Val Pro Met Glu Asp
   1               5                  10                  15

 Gly Asp Lys Arg Cys Lys Leu Leu Leu Gly Ile Gly Ile Leu Val
                  20                  25                  30

 Leu Leu Ile Ile Val Ile Leu Gly Val Pro Leu Ile Ile Phe Thr
                  35                  40                  45

 Ile Lys Ala Asn Ser Glu Ala Cys Arg Asp Gly Leu Arg Ala Val
                  50                  55                  60

 Met Glu Cys Arg Asn Val Thr His Leu Leu Gln Gln Glu Leu Thr
                  65                  70                  75

 Glu Ala Gln Lys Gly Phe Gln Asp Val Glu Ala Gln Ala Ala Thr
                  80                  85                  90

 Cys Asn His Thr Val Met Ala Leu Met Ala Ser Leu Asp Ala Glu
                  95                 100                 105

 Lys Ala Gln Gly Gln Lys Lys Val Glu Glu Leu Glu Gly Glu Ile
                 110                 115                 120

 Thr Thr Leu Asn His Lys Leu Gln Asp Ala Ser Ala Glu Val Glu
                 125                 130                 135

 Arg Leu Arg Arg Glu Asn Gln Val Leu Ser Val Arg Ile Ala Asp
                 140                 145                 150

 Lys Lys Tyr Tyr Pro Ser Ser Gln Asp Ser Ser Ser Ala Ala Ala
                 155                 160                 165

 Pro Gln Leu Leu Ile Val Leu Leu Gly Leu Ser Ala Leu Leu Gln
                 170                 175                 180

<210> 419
<211> 2214
<212> DNA
<213> Homo sapien

<400> 419
 gttgactgga ggcggaggtt gcagtgagcc gagatcgccc cactgcactc 50

 cagcctggtg actccgtctc aaaaaaaagg ggaggggggc gggggagagt 100

 tgaaagctta atatgtactt tgggggctat taaagcaaac atttcgacta 150

 aaggggcgaa tcctcgaatt gtgcgatcaa gcacccgaga ggagagttgg 200

 ggggggtcag gaggggtggg ggctccaggg aacgcccggg ggcctgggcc 250

 ggggtctcgc ggggcccttc cggaaggatc gcggcccccg aaggtgggcg 300

 tcccgcgggg ctccagtctc caggacgttc cgggaggctc cgcgctctgg 350

 gaggccggct gcgtggggtc cccgcgctgc agccgcagag gccccccagg 400

 gccgcggttc ccggagcggg aaagtcccgc gcgggggcgg tggcctcggg 450

 ggcgggacgg ggcgggggcg ggggcgcggg cggccgagcc gaatcccctc 500

 caccgggacg ccccgctgcc gctcgggaag aggcgggccc tgcgcgccct 550

 gcgctcgcca tggcggtttg ggcggcgacg tgagcggctc cgcggacccc 600

 gagcggggcc ccggccgcga cctgagccgc cgccgagcgc ccggggccat 650

 gcgaccgacg ctgctgtggt cgctgctgct gctgctcgga gtcttcgccg 700

 ccgccgccgc ggccccgcca gaccctcttt cccagctgcc cgctcctcag 750

 cacccgaaga ttcgcctgta caacgcagag caggtcctga gttgggagcc 800

 agtggccctg agcaatagca cgaggcctgt tgtctaccga gtgcagttta 850

 aatacaccga cagtaaatgg ttcacggccg acatcatgtc cataggggtg 900

 aattgtacac agatcacagc aacagagtgt gacttcactg ccgccagtcc 950

 ctcagcaggc ttcccaatgg atttcaatgt cactctacgc cttcgagctg 1000

 agctgggagc actccattct gcctgggtga caatgccttg gtttcaacac 1050

 tatcggaatg tgactgtcgg gcctccagaa aacattgagg tgaccccagg 1100

 agaaggctcc ctcatcatca ggttctcctc tccctttgac atcgctgata 1150

 cctccacggc ctttttttgt tattatgtcc attactggga aaaaggagga 1200

 atccaacagg tcaaaggccc tttcagaagc aactccattt cattggataa 1250

 cttaaaaccc tccagagtgt actgtttaca agtccaggca caactgcttt 1300

 ggaacaaaag taacatcttt agagtcgggc atttaagcaa catatcttgc 1350

 tacgaaacaa tggcagatgc ctccactgag cttcagcaag tcatcctgat 1400

 ctccgtggga acattttcgt tgctgtcggt gctggcagga gcctgtttct 1450

 tcctggtcct gaaatataga ggcctgatta aatactggtt tcacactcca 1500

 ccaagcatcc cattacagat agaagagtat ttaaaagacc caactcagcc 1550

 catcttagag gccttggaca aggacagctc accaaaggat gacgtctggg 1600

 actctgtgtc cattatctcg tttccggaaa aggagcaaga agatgttctc 1650

 caaacgcttt gaaccaaagc atgggcctag cccactggct ccctggaaga 1700

 gatcaagcca tcggagctgc tagagttctg tctggacttt ccagagacca 1750

 gtattccctt ttgctgcctc taaaaggcct gtccctgcag acatgagaga 1800

 cagcaggtct catgggggtg acaagctttt tttttttttt cttaaagaat 1850

 tttcaaaatc aaattccaga atgattttac ggagatatcc caggaaaatt 1900

 aaggcttctc ttaaacacta aaaaggcatg taattgcttg ttagcaaaat 1950

 ggatatgaca catctctgat acttttttca ttattggttg ggctgagcag 2000

 tcagaagacc tggtcgtcgt cttgactttg gcaaatgagc cggagcccct 2050

 tgggcaggtc acacaacctg tcccagcgag ggacactgag tggcccttca 2100

 tgtacatcca tggtgtgctg gcttaaaatg taattaatct tgtaaatata 2150

 ctcctagtaa tttaagattt tgtttttaaa ctggaaataa aagattgtat 2200

 agtgcatgtt tttt 2214

<210> 420
<211> 337
<212> PRT
<213> Homo sapien

<400> 420
 Met Arg Pro Thr Leu Leu Trp Ser Leu Leu Leu Leu Leu Gly Val
   1               5                  10                  15

 Phe Ala Ala Ala Ala Ala Ala Pro Pro Asp Pro Leu Ser Gln Leu
                  20                  25                  30

 Pro Ala Pro Gln His Pro Lys Ile Arg Leu Tyr Asn Ala Glu Gln
                  35                  40                  45

 Val Leu Ser Trp Glu Pro Val Ala Leu Ser Asn Ser Thr Arg Pro
                  50                  55                  60

 Val Val Tyr Arg Val Gln Phe Lys Tyr Thr Asp Ser Lys Trp Phe
                  65                  70                  75

 Thr Ala Asp Ile Met Ser Ile Gly Val Asn Cys Thr Gln Ile Thr
                  80                  85                  90

 Ala Thr Glu Cys Asp Phe Thr Ala Ala Ser Pro Ser Ala Gly Phe
                  95                 100                 105

 Pro Met Asp Phe Asn Val Thr Leu Arg Leu Arg Ala Glu Leu Gly
                 110                 115                 120

 Ala Leu His Ser Ala Trp Val Thr Met Pro Trp Phe Gln His Tyr
                 125                 130                 135

 Arg Asn Val Thr Val Gly Pro Pro Glu Asn Ile Glu Val Thr Pro
                 140                 145                 150

 Gly Glu Gly Ser Leu Ile Ile Arg Phe Ser Ser Pro Phe Asp Ile
                 155                 160                 165

 Ala Asp Thr Ser Thr Ala Phe Phe Cys Tyr Tyr Val His Tyr Trp
                 170                 175                 180

 Glu Lys Gly Gly Ile Gln Gln Val Lys Gly Pro Phe Arg Ser Asn
                 185                 190                 195

 Ser Ile Ser Leu Asp Asn Leu Lys Pro Ser Arg Val Tyr Cys Leu
                 200                 205                 210

 Gln Val Gln Ala Gln Leu Leu Trp Asn Lys Ser Asn Ile Phe Arg
                 215                 220                 225

 Val Gly His Leu Ser Asn Ile Ser Cys Tyr Glu Thr Met Ala Asp
                 230                 235                 240

 Ala Ser Thr Glu Leu Gln Gln Val Ile Leu Ile Ser Val Gly Thr
                 245                 250                 255

 Phe Ser Leu Leu Ser Val Leu Ala Gly Ala Cys Phe Phe Leu Val
                 260                 265                 270

 Leu Lys Tyr Arg Gly Leu Ile Lys Tyr Trp Phe His Thr Pro Pro
                 275                 280                 285

 Ser Ile Pro Leu Gln Ile Glu Glu Tyr Leu Lys Asp Pro Thr Gln
                 290                 295                 300

 Pro Ile Leu Glu Ala Leu Asp Lys Asp Ser Ser Pro Lys Asp Asp
                 305                 310                 315

 Val Trp Asp Ser Val Ser Ile Ile Ser Phe Pro Glu Lys Glu Gln
                 320                 325                 330

 Glu Asp Val Leu Gln Thr Leu
                 335

<210> 421
<211> 5611
<212> DNA
<213> Homo sapien

<400> 421
 gcgcgaccgt cccgggggtg gggccgggcg cagcggcgag aggaggcgaa 50

 ggtggctgcg gtagcagcag cgcggcagcc tcggacccag cccggagcgc 100

 agggcggccg ctgcaggtcc ccgctcccct ccccgtgcgt ccgcccatgg 150

 ccgccgccgg gcagctgtgc ttgctctacc tgtcggcggg gctcctgtcc 200

 cggctcggcg cagccttcaa cttggacact cgggaggaca acgtgatccg 250

 gaaatatgga gaccccggga gcctcttcgg cttctcgctg gccatgcact 300

 ggcaactgca gcccgaggac aagcggctgt tgctcgtggg ggccccgcgc 350

 ggagaagcgc ttccactgca gagagccaac agaacgggag ggctgtacag 400

 ctgcgacatc accgcccggg ggccatgcac gcggatcgag tttgataacg 450

 atgctgaccc cacgtcagaa agcaaggaag atcagtggat gggggtcacc 500

 gtccagagcc aaggtccagg gggcaaggtc gtgacatgtg ctcaccgata 550

 tgaaaaaagg cagcatgtta atacgaagca ggaatcccga gacatctttg 600

 ggcggtgtta tgtcctgagt cagaatctca ggattgaaga cgatatggat 650

 gggggagatt ggagcttttg tgatgggcga ttgagaggcc atgagaaatt 700

 tggctcttgc cagcaaggtg tagcagctac ttttactaaa gactttcatt 750

 acattgtatt tggagccccg ggtacttata actggaaagg gattgttcgt 800

 gtagagcaaa agaataacac tttttttgac atgaacatct ttgaagatgg 850

 gccttatgaa gttggtggag agactgagca tgatgaaagt ctcgttcctg 900

 ttcctgctaa cagttactta ggtttttctt tggactcagg gaaaggtatt 950

 gtttctaaag atgagatcac ttttgtatct ggtgctccca gagccaatca 1000

 cagtggagcc gtggttttgc tgaagagaga catgaagtct gcacatctcc 1050

 tccctgagca catattcgat ggagaaggtc tggcctcttc atttggctat 1100

 gatgtggcgg tggtggacct caacaaggat gggtggcaag atatagttat 1150

 tggagcccca cagtattttg atagagatgg agaagttgga ggtgcagtgt 1200

 atgtctacat gaaccagcaa ggcagatgga ataatgtgaa gccaattcgt 1250

 cttaatggaa ccaaagattc tatgtttggc attgcagtaa aaaatattgg 1300

 agatattaat caagatggct acccagatat tgcagttgga gctccgtatg 1350

 atgacttggg aaaggttttt atctatcatg gatctgcaaa tggaataaat 1400

 accaaaccaa cacaggttct caagggtata tcaccttatt ttggatattc 1450

 aattgctgga aacatggacc ttgatcgaaa ttcctaccct gatgttgctg 1500

 ttggttccct ctcagattca gtaactattt tcagatcccg gcctgtgatt 1550

 aatattcaga aaaccatcac agtaactcct aacagaattg acctccgcca 1600

 gaaaacagcg tgtggggcgc ctagtgggat atgcctccag gttaaatcct 1650

 gttttgaata tactgctaac cccgctggtt ataatccttc aatatcaatt 1700

 gtgggcacac ttgaagctga aaaagaaaga agaaaatctg ggctatcctc 1750

 aagagttcag tttcgaaacc aaggttctga gcccaaatat actcaagaac 1800

 taactctgaa gaggcagaaa cagaaagtgt gcatggagga aaccctgtgg 1850

 ctacaggata atatcagaga taaactgcgt cccattccca taactgcctc 1900

 agtggagatc caagagccaa gctctcgtag gcgagtgaat tcacttccag 1950

 aagttcttcc aattctgaat tcagatgaac ccaagacagc tcatattgat 2000

 gttcacttct taaaagaggg atgtggagac gacaatgtat gtaacagcaa 2050

 ccttaaacta gaatataaat tttgcacccg agaaggaaat caagacaaat 2100

 tttcttattt accaattcaa aaaggtgtac cagaactagt tctaaaagat 2150

 cagaaggata ttgctttaga aataacagtg acaaacagcc cttccaaccc 2200

 aaggaatccc acaaaagatg gcgatgacgc ccatgaggct aaactgattg 2250

 caacgtttcc agacacttta acctattctg catatagaga actgagggct 2300

 ttccctgaga aacagttgag ttgtgttgcc aaccagaatg gctcgcaagc 2350

 tgactgtgag ctcggaaatc cttttaaaag aaattcaaat gtcacttttt 2400

 atttggtttt aagtacaact gaagtcacct ttgacacccc atatctggat 2450

 attaatctga agttagaaac aacaagcaat caagataatt tggctccaat 2500

 tacagctaaa gcaaaagtgg ttattgaact gcttttatcg gtctcgggag 2550

 ttgctaaacc ttcccaggtg tattttggag gtacagttgt tggcgagcaa 2600

 gctatgaaat ctgaagatga agtgggaagt ttaatagagt atgaattcag 2650

 ggtaataaac ttaggtaaac ctcttacaaa cctcggcaca gcaaccttga 2700

 acattcagtg gccaaaagaa attagcaatg ggaaatggtt gctttatttg 2750

 gtgaaagtag aatccaaagg attggaaaag gtaacttgtg agccacaaaa 2800

 ggagataaac tccctgaacc taacggagtc tcacaactca agaaagaaac 2850

 gggaaattac tgaaaaacag atagatgata acagaaaatt ttctttattt 2900

 gctgaaagaa aataccagac tcttaactgt agcgtgaacg tgaactgtgt 2950

 gaacatcaga tgcccgctgc gggggctgga cagcaaggcg tctcttattt 3000

 tgcgctcgag gttatggaac agcacatttc tagaggaata ttccaaactg 3050

 aactacttgg acattctcat gcgagccttc attgatgtga ctgctgctgc 3100

 cgaaaatatc aggctgccaa atgcaggcac tcaggttcga gtgactgtgt 3150

 ttccctcaaa gactgtagct cagtattcgg gagtaccttg gtggatcatc 3200

 ctagtggcta ttctcgctgg gatcttgatg cttgctttat tagtgtttat 3250

 actatggaag tgtggtttct tcaagagaaa taagaaagat cattatgatg 3300

 ccacatatca caaggctgag atccatgctc agccatctga taaagagagg 3350

 cttacttctg atgcatagta ttgatctact tctgtaattg tgtggattct 3400

 ttaaacgctc taggtacgat gacagtgttc cccgatacca tgctgtaagg 3450

 atccggaaag aagagcgaga gatcaaagat gaaaagtata ttgataacct 3500

 tgaaaaaaaa cagtggatca caaagtggaa cagaaatgaa agctactcat 3550

 agcgggggcc taaaaaaaaa aaagcttcac agtacccaaa ctgctttttc 3600

 caactcagaa attcaatttg gatttaaaag cctgctcaat ccctgaggac 3650

 tgatttcaga gtgactacac acagtacgaa cctacagttt taactgtgga 3700

 tattgttacg tagcctaagg ctcctgtttt gcacagccaa atttaaaact 3750

 gttggaatgg atttttcttt aactgccgta atttaacttt ctgggttgcc 3800

 tttgtttttg gcgtggctga cttacatcat gtgttgggga agggcctgcc 3850

 cagttgcact caggtgacat cctccagata gtgtagctga ggaggcacct 3900

 acactcacct gcactaacag agtggccgtc ctaacctcgg gcctgctgcg 3950

 cagacgtcca tcacgttagc tgtcccacat cacaagacta tgccattggg 4000

 gtagttgtgt ttcaacggaa agtgctgtct taaactaaat gtgcaataga 4050

 aggtgatgtt gccatcctac cgtcttttcc tgtttcctag ctgtgtgaat 4100

 acctgctcac gtcaaatgca tacaagtttc attctccctt tcactaaaaa 4150

 cacacaggtg caacagactt gaatgctagt tatacttatt tgtatatggt 4200

 atttattttt tcttttcttt acaaaccatt ttgttattga ctaacaggcc 4250

 aaagagtctc cagtttaccc ttcaggttgg tttaatcaat cagaattaga 4300

 attagagcat gggagggtca tcactatgac ctaaattatt tactgcaaaa 4350

 agaaaatctt tataaatgta ccagagagag ttgttttaat aacttatcta 4400

 taaactataa cctctccttc atgacagcct ccaccccaca acccaaaagg 4450

 tttaagaaat agaattataa ctgtaaagat gtttatttca ggcattggat 4500

 attttttact ttagaagcct gcataatgtt tctggattta catactgtaa 4550

 cattcaggaa ttcttggaga agatgggttt attcactgaa ctctagtgcg 4600

 gtttactcac tgctgcaaat actgtatatt caggacttga aagaaatggt 4650

 gaatgcctat ggaactagtg gatccaaact gatccagtat aagactactg 4700

 aatctgctac caaaacagtt aatcagtgag tcgagtgttc tattttttgt 4750

 tttgtttcct cccctatctg tattcccaaa aattactttg gggctaattt 4800

 aacaagaact ttaaattgtg ttttaattgt aaaaatggca gggggtggaa 4850

 ttattactct atacattcaa cagagactga atagatatga aagctgattt 4900

 tttttaatta ccatgcttca caatgttaag ttatatgggg agcaacagca 4950

 aacaggtgct aatttgtttt ggatatagta taagcagtgt ctgtgttttg 5000

 aaagaataga acacagtttg tagtgccact gttgttttgg ggggggcttt 5050

 ttttcttttt ccggaaaatc cttaaacctt aagatactaa ggacgttgtt 5100

 ttggttgtac ttggaattct tagtcacaaa atatattttg tttacaaaaa 5150

 tttctgtaaa acaggttata acagtgttta aagtctcagt ttcttgcttg 5200

 gggaacttgt gtccctaatg tgttagattg ctagattgct aaggagctga 5250

 tacttgacag ttttttagac ctgtgttact aaaaaaaaga tgaatgtcgg 5300

 aaaagggtgt tgggagggtg gtcaacaaag aaacaaagat gttatggtgt 5350

 ttagacttat ggttgttaaa aatgtcatct caagtcaagt cactggtctg 5400

 tttgcatttg atacattttt gtactaacta gcattgtaaa attatttcat 5450

 gattagaaat tacctgtgga tatttgtata aaagtgtgaa ataaattttt 5500

 tataaaagtg ttcattgttt cgtaacacag cattgtatat gtgaagcaaa 5550

 ctctaaaatt ataaatgaca acctgaatta tctatttcat caaaaaaaaa 5600

 aaaaaaaaaa a 5611

<210> 422
<211> 1073
<212> PRT
<213> Homo sapien

<400> 422
 Met Ala Ala Ala Gly Gln Leu Cys Leu Leu Tyr Leu Ser Ala Gly
   1               5                  10                  15

 Leu Leu Ser Arg Leu Gly Ala Ala Phe Asn Leu Asp Thr Arg Glu
                  20                  25                  30

 Asp Asn Val Ile Arg Lys Tyr Gly Asp Pro Gly Ser Leu Phe Gly
                  35                  40                  45

 Phe Ser Leu Ala Met His Trp Gln Leu Gln Pro Glu Asp Lys Arg
                  50                  55                  60

 Leu Leu Leu Val Gly Ala Pro Arg Gly Glu Ala Leu Pro Leu Gln
                  65                  70                  75

 Arg Ala Asn Arg Thr Gly Gly Leu Tyr Ser Cys Asp Ile Thr Ala
                  80                  85                  90

 Arg Gly Pro Cys Thr Arg Ile Glu Phe Asp Asn Asp Ala Asp Pro
                  95                 100                 105

 Thr Ser Glu Ser Lys Glu Asp Gln Trp Met Gly Val Thr Val Gln
                 110                 115                 120

 Ser Gln Gly Pro Gly Gly Lys Val Val Thr Cys Ala His Arg Tyr
                 125                 130                 135

 Glu Lys Arg Gln His Val Asn Thr Lys Gln Glu Ser Arg Asp Ile
                 140                 145                 150

 Phe Gly Arg Cys Tyr Val Leu Ser Gln Asn Leu Arg Ile Glu Asp
                 155                 160                 165

 Asp Met Asp Gly Gly Asp Trp Ser Phe Cys Asp Gly Arg Leu Arg
                 170                 175                 180

 Gly His Glu Lys Phe Gly Ser Cys Gln Gln Gly Val Ala Ala Thr
                 185                 190                 195

 Phe Thr Lys Asp Phe His Tyr Ile Val Phe Gly Ala Pro Gly Thr
                 200                 205                 210

 Tyr Asn Trp Lys Gly Ile Val Arg Val Glu Gln Lys Asn Asn Thr
                 215                 220                 225

 Phe Phe Asp Met Asn Ile Phe Glu Asp Gly Pro Tyr Glu Val Gly
                 230                 235                 240

 Gly Glu Thr Glu His Asp Glu Ser Leu Val Pro Val Pro Ala Asn
                 245                 250                 255

 Ser Tyr Leu Gly Phe Ser Leu Asp Ser Gly Lys Gly Ile Val Ser
                 260                 265                 270

 Lys Asp Glu Ile Thr Phe Val Ser Gly Ala Pro Arg Ala Asn His
                 275                 280                 285

 Ser Gly Ala Val Val Leu Leu Lys Arg Asp Met Lys Ser Ala His
                 290                 295                 300

 Leu Leu Pro Glu His Ile Phe Asp Gly Glu Gly Leu Ala Ser Ser
                 305                 310                 315

 Phe Gly Tyr Asp Val Ala Val Val Asp Leu Asn Lys Asp Gly Trp
                 320                 325                 330

 Gln Asp Ile Val Ile Gly Ala Pro Gln Tyr Phe Asp Arg Asp Gly
                 335                 340                 345

 Glu Val Gly Gly Ala Val Tyr Val Tyr Met Asn Gln Gln Gly Arg
                 350                 355                 360

 Trp Asn Asn Val Lys Pro Ile Arg Leu Asn Gly Thr Lys Asp Ser
                 365                 370                 375

 Met Phe Gly Ile Ala Val Lys Asn Ile Gly Asp Ile Asn Gln Asp
                 380                 385                 390

 Gly Tyr Pro Asp Ile Ala Val Gly Ala Pro Tyr Asp Asp Leu Gly
                 395                 400                 405

 Lys Val Phe Ile Tyr His Gly Ser Ala Asn Gly Ile Asn Thr Lys
                 410                 415                 420

 Pro Thr Gln Val Leu Lys Gly Ile Ser Pro Tyr Phe Gly Tyr Ser
                 425                 430                 435

 Ile Ala Gly Asn Met Asp Leu Asp Arg Asn Ser Tyr Pro Asp Val
                 440                 445                 450

 Ala Val Gly Ser Leu Ser Asp Ser Val Thr Ile Phe Arg Ser Arg
                 455                 460                 465

 Pro Val Ile Asn Ile Gln Lys Thr Ile Thr Val Thr Pro Asn Arg
                 470                 475                 480

 Ile Asp Leu Arg Gln Lys Thr Ala Cys Gly Ala Pro Ser Gly Ile
                 485                 490                 495

 Cys Leu Gln Val Lys Ser Cys Phe Glu Tyr Thr Ala Asn Pro Ala
                 500                 505                 510

 Gly Tyr Asn Pro Ser Ile Ser Ile Val Gly Thr Leu Glu Ala Glu
                 515                 520                 525

 Lys Glu Arg Arg Lys Ser Gly Leu Ser Ser Arg Val Gln Phe Arg
                 530                 535                 540

 Asn Gln Gly Ser Glu Pro Lys Tyr Thr Gln Glu Leu Thr Leu Lys
                 545                 550                 555

 Arg Gln Lys Gln Lys Val Cys Met Glu Glu Thr Leu Trp Leu Gln
                 560                 565                 570

 Asp Asn Ile Arg Asp Lys Leu Arg Pro Ile Pro Ile Thr Ala Ser
                 575                 580                 585

 Val Glu Ile Gln Glu Pro Ser Ser Arg Arg Arg Val Asn Ser Leu
                 590                 595                 600

 Pro Glu Val Leu Pro Ile Leu Asn Ser Asp Glu Pro Lys Thr Ala
                 605                 610                 615

 His Ile Asp Val His Phe Leu Lys Glu Gly Cys Gly Asp Asp Asn
                 620                 625                 630

 Val Cys Asn Ser Asn Leu Lys Leu Glu Tyr Lys Phe Cys Thr Arg
                 635                 640                 645

 Glu Gly Asn Gln Asp Lys Phe Ser Tyr Leu Pro Ile Gln Lys Gly
                 650                 655                 660

 Val Pro Glu Leu Val Leu Lys Asp Gln Lys Asp Ile Ala Leu Glu
                 665                 670                 675

 Ile Thr Val Thr Asn Ser Pro Ser Asn Pro Arg Asn Pro Thr Lys
                 680                 685                 690

 Asp Gly Asp Asp Ala His Glu Ala Lys Leu Ile Ala Thr Phe Pro
                 695                 700                 705

 Asp Thr Leu Thr Tyr Ser Ala Tyr Arg Glu Leu Arg Ala Phe Pro
                 710                 715                 720

 Glu Lys Gln Leu Ser Cys Val Ala Asn Gln Asn Gly Ser Gln Ala
                 725                 730                 735

 Asp Cys Glu Leu Gly Asn Pro Phe Lys Arg Asn Ser Asn Val Thr
                 740                 745                 750

 Phe Tyr Leu Val Leu Ser Thr Thr Glu Val Thr Phe Asp Thr Pro
                 755                 760                 765

 Tyr Leu Asp Ile Asn Leu Lys Leu Glu Thr Thr Ser Asn Gln Asp
                 770                 775                 780

 Asn Leu Ala Pro Ile Thr Ala Lys Ala Lys Val Val Ile Glu Leu
                 785                 790                 795

 Leu Leu Ser Val Ser Gly Val Ala Lys Pro Ser Gln Val Tyr Phe
                 800                 805                 810

 Gly Gly Thr Val Val Gly Glu Gln Ala Met Lys Ser Glu Asp Glu
                 815                 820                 825

 Val Gly Ser Leu Ile Glu Tyr Glu Phe Arg Val Ile Asn Leu Gly
                 830                 835                 840

 Lys Pro Leu Thr Asn Leu Gly Thr Ala Thr Leu Asn Ile Gln Trp
                 845                 850                 855

 Pro Lys Glu Ile Ser Asn Gly Lys Trp Leu Leu Tyr Leu Val Lys
                 860                 865                 870

 Val Glu Ser Lys Gly Leu Glu Lys Val Thr Cys Glu Pro Gln Lys
                 875                 880                 885

 Glu Ile Asn Ser Leu Asn Leu Thr Glu Ser His Asn Ser Arg Lys
                 890                 895                 900

 Lys Arg Glu Ile Thr Glu Lys Gln Ile Asp Asp Asn Arg Lys Phe
                 905                 910                 915

 Ser Leu Phe Ala Glu Arg Lys Tyr Gln Thr Leu Asn Cys Ser Val
                 920                 925                 930

 Asn Val Asn Cys Val Asn Ile Arg Cys Pro Leu Arg Gly Leu Asp
                 935                 940                 945

 Ser Lys Ala Ser Leu Ile Leu Arg Ser Arg Leu Trp Asn Ser Thr
                 950                 955                 960

 Phe Leu Glu Glu Tyr Ser Lys Leu Asn Tyr Leu Asp Ile Leu Met
                 965                 970                 975

 Arg Ala Phe Ile Asp Val Thr Ala Ala Ala Glu Asn Ile Arg Leu
                 980                 985                 990

 Pro Asn Ala Gly Thr Gln Val Arg Val Thr Val Phe Pro Ser Lys
                 995                1000                1005

 Thr Val Ala Gln Tyr Ser Gly Val Pro Trp Trp Ile Ile Leu Val
                1010                1015                1020

 Ala Ile Leu Ala Gly Ile Leu Met Leu Ala Leu Leu Val Phe Ile
                1025                1030                1035

 Leu Trp Lys Cys Gly Phe Phe Lys Arg Asn Lys Lys Asp His Tyr
                1040                1045                1050

 Asp Ala Thr Tyr His Lys Ala Glu Ile His Ala Gln Pro Ser Asp
                1055                1060                1065

 Lys Glu Arg Leu Thr Ser Asp Ala
                1070

<210> 423
<211> 782
<212> DNA
<213> Homo sapien

<400> 423
 aggggcctta gcgtgccgca tcgccgagat ccagcgccca gagagacacc 50

 agagaaccca ccatggcccc ctttgagccc ctggcttctg gcatcctgtt 100

 gttgctgtgg ctgatagccc ccagcagggc ctgcacctgt gtcccacccc 150

 acccacagac ggccttctgc aattccgacc tcgtcatcag ggccaagttc 200

 gtggggacac cagaagtcaa ccagaccacc ttataccagc gttatgagat 250

 caagatgacc aagatgtata aagggttcca agccttaggg gatgccgctg 300

 acatccggtt cgtctacacc cccgccatgg agagtgtctg cggatacttc 350

 cacaggtccc acaaccgcag cgaggagttt ctcattgctg gaaaactgca 400

 ggatggactc ttgcacatca ctacctgcag tttcgtggct ccctggaaca 450

 gcctgagctt agctcagcgc cggggcttca ccaagaccta cactgttggc 500

 tgtgaggaat gcacagtgtt tccctgttta tccatcccct gcaaactgca 550

 gagtggcact cattgcttgt ggacggacca gctcctccaa ggctctgaaa 600

 agggcttcca gtcccgtcac cttgcctgcc tgcctcggga gccagggctg 650

 tgcacctggc agtccctgcg gtcccagata gcctgaatcc tgcccggagt 700

 ggaactgaag cctgcacagt gtccaccctg ttcccactcc catctttctt 750

 ccggacaatg aaataaagag ttaccaccca gc 782

<210> 424
<211> 207
<212> PRT
<213> Homo sapien

<400> 424
 Met Ala Pro Phe Glu Pro Leu Ala Ser Gly Ile Leu Leu Leu Leu
   1               5                  10                  15

 Trp Leu Ile Ala Pro Ser Arg Ala Cys Thr Cys Val Pro Pro His
                  20                  25                  30

 Pro Gln Thr Ala Phe Cys Asn Ser Asp Leu Val Ile Arg Ala Lys
                  35                  40                  45

 Phe Val Gly Thr Pro Glu Val Asn Gln Thr Thr Leu Tyr Gln Arg
                  50                  55                  60

 Tyr Glu Ile Lys Met Thr Lys Met Tyr Lys Gly Phe Gln Ala Leu
                  65                  70                  75

 Gly Asp Ala Ala Asp Ile Arg Phe Val Tyr Thr Pro Ala Met Glu
                  80                  85                  90

 Ser Val Cys Gly Tyr Phe His Arg Ser His Asn Arg Ser Glu Glu
                  95                 100                 105

 Phe Leu Ile Ala Gly Lys Leu Gln Asp Gly Leu Leu His Ile Thr
                 110                 115                 120

 Thr Cys Ser Phe Val Ala Pro Trp Asn Ser Leu Ser Leu Ala Gln
                 125                 130                 135

 Arg Arg Gly Phe Thr Lys Thr Tyr Thr Val Gly Cys Glu Glu Cys
                 140                 145                 150

 Thr Val Phe Pro Cys Leu Ser Ile Pro Cys Lys Leu Gln Ser Gly
                 155                 160                 165

 Thr His Cys Leu Trp Thr Asp Gln Leu Leu Gln Gly Ser Glu Lys
                 170                 175                 180

 Gly Phe Gln Ser Arg His Leu Ala Cys Leu Pro Arg Glu Pro Gly
                 185                 190                 195

 Leu Cys Thr Trp Gln Ser Leu Arg Ser Gln Ile Ala
                 200                 205

<210> 425
<211> 1480
<212> DNA
<213> Homo sapien

<400> 425
 cgcgagccgg gaccacgccg acccagcgtg cccaggccga ggaaagcgcg 50

 gcggcggcag tccgaagacc caccggactg aaagagaagg acgaggtcat 100

 cttcggacgg gaggggcaag ccagccatcc tgggacccca ggcgtgcagg 150

 ttctctttga gggtattcca ccctgcaaaa agcatgtatt catggtcagc 200

 tctcagcaag gccagtagca gagtggtaaa ggccttggcc ctccaaggct 250

 gggaaaagac aatgacaagt caaatccaga cctatgttgg atgttggtct 300

 actaggtgac tgtctcctgg aaatgttatg cagctcagca aggtgaagtt 350

 tcgaaatcag tatgacaatg atgtcactgt ttggagcccc cagggcagga 400

 ttcatcaaat tgaatatgca atggaagctg ttaaacaagg ttcagccaca 450

 gttggtctga aatcaaaaac tcatgcagtt ttggttgcat tgaaaagggc 500

 gcaatcagag cttgcagctc atcagaaaaa aattctccat gttgacaacc 550

 atattggtat ctcaattgcg gggcttactg ctgatgctag actgttatgt 600

 aattttatgc gtcaggagtg tttggattcc agatttgtat tcgatagacc 650

 actgcctgtg tctcgtcttg tatctctaat tggaagcaag acccagatac 700

 caacacaacg atatggccgg agaccatatg gtgttggtct ccttattgct 750

 ggttatgatg atatgggccc tcacattttc caaacctgtc catctgctaa 800

 ctattttgac tgcagagcca tgtccattgg agcccgttcc caatcagctc 850

 gtacttactt ggagagacat atgtctgaat ttatggagtg taatttaaat 900

 gaactagtta aacatggtct gcgtgcctta agagagacgc ttcctgcaga 950

 acaggacctg actacaaaga atgtttccat tggaattgtt ggtaaagact 1000

 tggagtttac aatctatgat gatgatgatg tgtctccatt cctggaaggt 1050

 cttgaagaaa gaccacagag aaaggcacag cctgctcaac ctgctgatga 1100

 acctgcagaa aaggctgatg aaccaatgga acattaagtg ataagccagt 1150

 ctatatatgt attatcaaat atgtaagaat acaggcacca catactgatg 1200

 acaataatct atactttgaa ccaaaagttg cagagtggtg gaatgctatg 1250

 ttttaggaat cagtccagat gtgagttttt tccaagcaac ctcactgaaa 1300

 cctatataat ggaatacatt tttctttgaa agggtctgta taatcatttt 1350

 ctagaaagta tgggtatcta tactaatgtt tttatatgaa gaacataggt 1400

 gtctttgtgg ttttaaagac aactgtgaaa taaaattgtt tcaccgcctg 1450

 gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1480

<210> 426
<211> 269
<212> PRT
<213> Homo sapien

<400> 426
 Met Gln Leu Ser Lys Val Lys Phe Arg Asn Gln Tyr Asp Asn Asp
   1               5                  10                  15

 Val Thr Val Trp Ser Pro Gln Gly Arg Ile His Gln Ile Glu Tyr
                  20                  25                  30

 Ala Met Glu Ala Val Lys Gln Gly Ser Ala Thr Val Gly Leu Lys
                  35                  40                  45

 Ser Lys Thr His Ala Val Leu Val Ala Leu Lys Arg Ala Gln Ser
                  50                  55                  60

 Glu Leu Ala Ala His Gln Lys Lys Ile Leu His Val Asp Asn His
                  65                  70                  75

 Ile Gly Ile Ser Ile Ala Gly Leu Thr Ala Asp Ala Arg Leu Leu
                  80                  85                  90

 Cys Asn Phe Met Arg Gln Glu Cys Leu Asp Ser Arg Phe Val Phe
                  95                 100                 105

 Asp Arg Pro Leu Pro Val Ser Arg Leu Val Ser Leu Ile Gly Ser
                 110                 115                 120

 Lys Thr Gln Ile Pro Thr Gln Arg Tyr Gly Arg Arg Pro Tyr Gly
                 125                 130                 135

 Val Gly Leu Leu Ile Ala Gly Tyr Asp Asp Met Gly Pro His Ile
                 140                 145                 150

 Phe Gln Thr Cys Pro Ser Ala Asn Tyr Phe Asp Cys Arg Ala Met
                 155                 160                 165

 Ser Ile Gly Ala Arg Ser Gln Ser Ala Arg Thr Tyr Leu Glu Arg
                 170                 175                 180

 His Met Ser Glu Phe Met Glu Cys Asn Leu Asn Glu Leu Val Lys
                 185                 190                 195

 His Gly Leu Arg Ala Leu Arg Glu Thr Leu Pro Ala Glu Gln Asp
                 200                 205                 210

 Leu Thr Thr Lys Asn Val Ser Ile Gly Ile Val Gly Lys Asp Leu
                 215                 220                 225

 Glu Phe Thr Ile Tyr Asp Asp Asp Asp Val Ser Pro Phe Leu Glu
                 230                 235                 240

 Gly Leu Glu Glu Arg Pro Gln Arg Lys Ala Gln Pro Ala Gln Pro
                 245                 250                 255

 Ala Asp Glu Pro Ala Glu Lys Ala Asp Glu Pro Met Glu His
                 260                 265

<210> 427
<211> 2095
<212> DNA
<213> Homo sapien

<400> 427
 gcgcctgtca gggaagcggc gcgcgcgcgc gggcggcggg cgggctgggg 50

 atccgccgcg cagtgccagc gccagcgcca gacccgcgcc ccgcgctctc 100

 cggcccgtcg cctgccttgg gactcgcgag cccgcactcc cgccctgcct 150

 gttcgctgcc cgagtatgga gctgctgtgt tgcgaaggca cccggcacgc 200

 gccccgggcc gggccggacc cgcggctgct gggggaccag cgtgtcctgc 250

 agagcctgct ccgcctggag gagcgctacg taccccgcgc ctcctacttc 300

 cagtgcgtgc agcgggagat caagccgcac atgcggaaga tgctggctta 350

 ctggatgctg gaggtatgtg aggagcagcg ctgtgaggag gaagtcttcc 400

 ccctggccat gaactacctg gatcgctacc tgtcttgcgt ccccacccga 450

 aaggcgcagt tgcagctcct gggtgcggtc tgcatgctgc tggcctccaa 500

 gctgcgcgag accacgcccc tgaccatcga aaaactgtgc atctacaccg 550

 accacgctgt ctctccccgc cagttgcggg actgggaggt gctggtccta 600

 gggaagctca agtgggacct ggctgctgtg attgcacatg atttcctggc 650

 cttcattctg caccggctct ctctgccccg tgaccgacag gccttggtca 700

 aaaagcatgc ccagaccttt ttggccctct gtgctacaga ttataccttt 750

 gccatgtacc cgccatccat gatcgccacg ggcagcattg gggctgcagt 800

 gcaaggcctg ggtgcctgct ccatgtccgg ggatgagctc acagagctgc 850

 tggcagggat cactggcact gaagtggact gcctgcgggc ctgtcaggag 900

 cagatcgaag ctgcactcag ggagagcctc agggaagcct ctcagaccag 950

 ctccagccca gcgcccaaag ccccccgggg ctccagcagc caagggccca 1000

 gccagaccag cactcctaca gatgtcacag ccatacacct gtagccctgg 1050

 agaggccctc tggagtggcc actaagcaga ggaggggccg ctgccaccca 1100

 cctccctgcc tccaggaacc acaccacatc taagcctgaa ggggcgtctg 1150

 ttcccccttc acaaagccca agggatctgg tcctacccat ccccgcagtg 1200

 tgcactaagg ggcccggcca gccatgtctg catttcggtg gctagtcaag 1250

 ctcctcctcc ctgcatctga ccagcagcgc ctttcccaac tctagctggg 1300

 ggtgggccag gctgatggga cagaattgga tacatacacc agcattcctt 1350

 ttgaacgccc ccccccaccc ctgggggctc tcatgttttc aactgccaaa 1400

 atgctctagt gccttctaaa ggtgttgtcc cttctagggt tattgcattt 1450

 ggattggggt ccctctaaaa tttaatgcat gatagacaca tatgaggggg 1500

 aatagtctag atggctcctc tcagtacttt ggaggcccct atgtagtccg 1550

 tgctgacagc tgctcctaga gggaggggcc taggcctcag ccagagaagc 1600

 tataaattcc tctttgcttt gctttctgct cagcttctcc tgtgtgattg 1650

 acagctttgc tgctgaaggc tcattttaat ttattaattg ctttgagcac 1700

 aactttaaga ggacataatg ggggcctggc catcccacaa gtggtggtaa 1750

 ccctggtggt tgctgttttc ctcccttctg ctactggcaa aaggatcttt 1800

 gtggccaagg agctgctata gcctggggtg gggtcatgcc ctcctctccc 1850

 attgtccctc tgccccatcc tccagcaggg aaaatgcagc agggatgccc 1900

 tggaggtggc tgagcccctg tctagagagg gaggcaagcc ctgttgacac 1950

 aggtctttcc taaggctgca aggtttaggc tggtggccca ggaccatcat 2000

 cctactgtaa taaagatgat tgtgaaataa aactggcttt ggcttcttgg 2050

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 2095

<210> 428
<211> 292
<212> PRT
<213> Homo sapien

<400> 428
 Met Glu Leu Leu Cys Cys Glu Gly Thr Arg His Ala Pro Arg Ala
   1               5                  10                  15

 Gly Pro Asp Pro Arg Leu Leu Gly Asp Gln Arg Val Leu Gln Ser
                  20                  25                  30

 Leu Leu Arg Leu Glu Glu Arg Tyr Val Pro Arg Ala Ser Tyr Phe
                  35                  40                  45

 Gln Cys Val Gln Arg Glu Ile Lys Pro His Met Arg Lys Met Leu
                  50                  55                  60

 Ala Tyr Trp Met Leu Glu Val Cys Glu Glu Gln Arg Cys Glu Glu
                  65                  70                  75

 Glu Val Phe Pro Leu Ala Met Asn Tyr Leu Asp Arg Tyr Leu Ser
                  80                  85                  90

 Cys Val Pro Thr Arg Lys Ala Gln Leu Gln Leu Leu Gly Ala Val
                  95                 100                 105

 Cys Met Leu Leu Ala Ser Lys Leu Arg Glu Thr Thr Pro Leu Thr
                 110                 115                 120

 Ile Glu Lys Leu Cys Ile Tyr Thr Asp His Ala Val Ser Pro Arg
                 125                 130                 135

 Gln Leu Arg Asp Trp Glu Val Leu Val Leu Gly Lys Leu Lys Trp
                 140                 145                 150

 Asp Leu Ala Ala Val Ile Ala His Asp Phe Leu Ala Phe Ile Leu
                 155                 160                 165

 His Arg Leu Ser Leu Pro Arg Asp Arg Gln Ala Leu Val Lys Lys
                 170                 175                 180

 His Ala Gln Thr Phe Leu Ala Leu Cys Ala Thr Asp Tyr Thr Phe
                 185                 190                 195

 Ala Met Tyr Pro Pro Ser Met Ile Ala Thr Gly Ser Ile Gly Ala
                 200                 205                 210

 Ala Val Gln Gly Leu Gly Ala Cys Ser Met Ser Gly Asp Glu Leu
                 215                 220                 225

 Thr Glu Leu Leu Ala Gly Ile Thr Gly Thr Glu Val Asp Cys Leu
                 230                 235                 240

 Arg Ala Cys Gln Glu Gln Ile Glu Ala Ala Leu Arg Glu Ser Leu
                 245                 250                 255

 Arg Glu Ala Ser Gln Thr Ser Ser Ser Pro Ala Pro Lys Ala Pro
                 260                 265                 270

 Arg Gly Ser Ser Ser Gln Gly Pro Ser Gln Thr Ser Thr Pro Thr
                 275                 280                 285

 Asp Val Thr Ala Ile His Leu
                 290

<210> 429
<211> 1568
<212> DNA
<213> Homo sapien

<400> 429
 cgcaacgccg gtgcctgagg agcgatgccg agggaaatca tcaccctaca 50

 gttgggccag tgcggcaatc agattgggtt cgagttctgg aaacagctgt 100

 gcgccgagca tggtatcagc cccgaggcga tcgtggagga gttcgccacc 150

 gagggcactg accgcaagga cgtctttttc taccaggcag acgatgagca 200

 ctacatcccc cgggccgtgc tgctggactt ggaaccccgg gtgatccact 250

 ccatcctcaa ctccccctat gccaagctct acaacccaga gaacatctac 300

 ctgtcggaac atggaggagg agctggcaac aactgggcca gcggattctc 350

 ccagggagaa aagatccatg aggacatttt tgacatcata gaccgggagg 400

 cagatggtag tgacagtcta gagggctttg tgctgtgtca ctccattgct 450

 ggggggacag gctctggact gggttcctac ctcttagaac ggctgaatga 500

 caggtatcct aagaagctgg tgcagacata ctcagtgttt cccaaccagg 550

 acgagatgag cgatgtggtg gtccagcctt acaattcact cctcacactc 600

 aagaggctga cgcagaatgc agactgtctg gtggtgctgg acaacacagc 650

 cctgaaccgg attgccacag accgcctgca catccagaac ccatccttct 700

 cccagatcaa ccagctggtg tctaccatca tgtcagccag caccaccacc 750

 ctgcgctacc ctggctacat gaacaatgac ctcatcggcc tcatcgcctc 800

 gctcattccc accccacggc tccacttcct catgaccggc tacacccctc 850

 tcactacgga ccagtcagtg gccagcgtga ggaagaccac ggtcctggat 900

 gtcatgaggc ggctgctgca gcccaagaac gtgatggtgt ccacaggccg 950

 agaccgccag accaaccact gctacatcgc catcctcaac atcatccagg 1000

 gagaggtgga ccccacccag gtccacaaga gcttgcagag gatccgggaa 1050

 cgcaagttgg ccaacttcat cccgtggggc cccgccagca tccaggtggc 1100

 cctgtcgagg aagtctccct acctgccctc ggcccaccgg gtcagcgggc 1150

 tcatgatggc caaccacacc agcatctcct cgctcttcga gagaacctgt 1200

 cgccagtatg acaagctgcg taagcgggag gccttcctgg agcagttccg 1250

 caaggaggac atgttcaagg acaactttga tgagatggac acatccaggg 1300

 agattgtgca gcagctcatc gatgagtacc atgcggccac acggccagac 1350

 tacatctcct ggggcaccca ggagcagtga gtcccccagg acaggggacc 1400

 ctcatctgcc ttactggttg gcccaagccc tgcctgactg accaccccct 1450

 cagagcacag atcagggacc tcacgcatct ctttctcata tacatggact 1500

 ctctgttggc ctgcaaacac atttacttct cctcttatga gactatttat 1550

 ctttaataaa gcactggg 1568

<210> 430
<211> 451
<212> PRT
<213> Homo sapien

<400> 430
 Met Pro Arg Glu Ile Ile Thr Leu Gln Leu Gly Gln Cys Gly Asn
   1               5                  10                  15

 Gln Ile Gly Phe Glu Phe Trp Lys Gln Leu Cys Ala Glu His Gly
                  20                  25                  30

 Ile Ser Pro Glu Ala Ile Val Glu Glu Phe Ala Thr Glu Gly Thr
                  35                  40                  45

 Asp Arg Lys Asp Val Phe Phe Tyr Gln Ala Asp Asp Glu His Tyr
                  50                  55                  60

 Ile Pro Arg Ala Val Leu Leu Asp Leu Glu Pro Arg Val Ile His
                  65                  70                  75

 Ser Ile Leu Asn Ser Pro Tyr Ala Lys Leu Tyr Asn Pro Glu Asn
                  80                  85                  90

 Ile Tyr Leu Ser Glu His Gly Gly Gly Ala Gly Asn Asn Trp Ala
                  95                 100                 105

 Ser Gly Phe Ser Gln Gly Glu Lys Ile His Glu Asp Ile Phe Asp
                 110                 115                 120

 Ile Ile Asp Arg Glu Ala Asp Gly Ser Asp Ser Leu Glu Gly Phe
                 125                 130                 135

 Val Leu Cys His Ser Ile Ala Gly Gly Thr Gly Ser Gly Leu Gly
                 140                 145                 150

 Ser Tyr Leu Leu Glu Arg Leu Asn Asp Arg Tyr Pro Lys Lys Leu
                 155                 160                 165

 Val Gln Thr Tyr Ser Val Phe Pro Asn Gln Asp Glu Met Ser Asp
                 170                 175                 180

 Val Val Val Gln Pro Tyr Asn Ser Leu Leu Thr Leu Lys Arg Leu
                 185                 190                 195

 Thr Gln Asn Ala Asp Cys Leu Val Val Leu Asp Asn Thr Ala Leu
                 200                 205                 210

 Asn Arg Ile Ala Thr Asp Arg Leu His Ile Gln Asn Pro Ser Phe
                 215                 220                 225

 Ser Gln Ile Asn Gln Leu Val Ser Thr Ile Met Ser Ala Ser Thr
                 230                 235                 240

 Thr Thr Leu Arg Tyr Pro Gly Tyr Met Asn Asn Asp Leu Ile Gly
                 245                 250                 255

 Leu Ile Ala Ser Leu Ile Pro Thr Pro Arg Leu His Phe Leu Met
                 260                 265                 270

 Thr Gly Tyr Thr Pro Leu Thr Thr Asp Gln Ser Val Ala Ser Val
                 275                 280                 285

 Arg Lys Thr Thr Val Leu Asp Val Met Arg Arg Leu Leu Gln Pro
                 290                 295                 300

 Lys Asn Val Met Val Ser Thr Gly Arg Asp Arg Gln Thr Asn His
                 305                 310                 315

 Cys Tyr Ile Ala Ile Leu Asn Ile Ile Gln Gly Glu Val Asp Pro
                 320                 325                 330

 Thr Gln Val His Lys Ser Leu Gln Arg Ile Arg Glu Arg Lys Leu
                 335                 340                 345

 Ala Asn Phe Ile Pro Trp Gly Pro Ala Ser Ile Gln Val Ala Leu
                 350                 355                 360

 Ser Arg Lys Ser Pro Tyr Leu Pro Ser Ala His Arg Val Ser Gly
                 365                 370                 375

 Leu Met Met Ala Asn His Thr Ser Ile Ser Ser Leu Phe Glu Arg
                 380                 385                 390

 Thr Cys Arg Gln Tyr Asp Lys Leu Arg Lys Arg Glu Ala Phe Leu
                 395                 400                 405

 Glu Gln Phe Arg Lys Glu Asp Met Phe Lys Asp Asn Phe Asp Glu
                 410                 415                 420

 Met Asp Thr Ser Arg Glu Ile Val Gln Gln Leu Ile Asp Glu Tyr
                 425                 430                 435

 His Ala Ala Thr Arg Pro Asp Tyr Ile Ser Trp Gly Thr Gln Glu
                 440                 445                 450

 Gln


<210> 431
<211> 4336
<212> DNA
<213> Homo sapien

<400> 431
 ggcgggtccc gcggcgaggc agctcctggg cataagctgt ggccatgact 50

 actgaagtag gctctgtgtc tgaagtgaag aaggactcta gccagttagg 100

 aacagatgca accaaggaaa aacctaaaga agtagcagaa aatcagcaga 150

 atcagtcttc cgatccagag gaggaaaaag gttcccagcc acctcctgca 200

 gctgaaagcc aaagtagtct acgccgccag aagagagaga aggaaacatc 250

 ggagagcagg ggtatttctc ggttcatacc gccatggctt aagaagcaaa 300

 agtcatatac cttagtagtg gccaaagatg gaggagataa aaaagagcct 350

 acccaagctg ttgttgaaga acaggtctta gataaagagg aaccccttcc 400

 agaagaacag agacaggcta agggtgatgc tgaagaaatg gctcagaaga 450

 aacaagagat taaagttgaa gtcaaggaag aaaaaccctc agtgagcaag 500

 gaagaaaaac cctcagtgag caaagtggag atgcagccta ctgaattagt 550

 aagtaaggag agagaagaga aggtaaaaga aacacaggaa gacaaattag 600

 aaggaggagc agcaaaaagg gagaccaagg aagtgcagac caatgagctg 650

 aaagcagaga aggcatctca aaaagtcacc aagaagacca aaactgtcca 700

 gtgtaaagtg accctcttag atggcaccga atacagctgt gacctggaga 750

 aacatgccaa gggacaagtg ttatttgaca aagtgtgtga acacctcaat 800

 ctcttggaga aagactactt tggacttttg tttcaggaaa gccctgagca 850

 gaaaaactgg ttagatcctg ctaaagaaat aaagagacaa ctgagaaacc 900

 ttccatggct attcactttt aatgtgaagt tttatcctcc tgatccttct 950

 caattgactg aagatatcac cagatacttc ttgtgccttc agctccggca 1000

 ggacattgcc tctggccgcc tgccctgctc ttttgtgact catgctctcc 1050

 tgggatccta caccctgcag gctgaacttg gtgactatga cccagaagaa 1100

 catggcagca tcgacctcag tgaattccag tttgccccta ctcagactaa 1150

 ggagctggaa gagaaggtgg cagagctgca caaaacccac aggggcttat 1200

 cgccagcaca agctgattcc cagttcttag aaaatgcaaa gaggctttcc 1250

 atgtatggtg ttgacctaca tcatgccaag gactcagaag gtgtggacat 1300

 caagctgggc gtgtgtgcta atggacttct catttacaaa gacagactgc 1350

 gaatcaatcg ttttgcttgg ccgaaaatct taaaaatttc ctataaacgc 1400

 agtaacttct acattaaagt cagaccggca gagctggaac agtttgagag 1450

 taccattgga ttcaaactgc caaaccaccg ggcagcgaaa agactatgga 1500

 aagtgtgcgt ggagcatcat actttctaca ggcttgtttc tccagagcag 1550

 ccaccaaaag ccaagttcct gaccttgggg tccaaatttc gctatagtgg 1600

 ccgcacccaa gcacagaccc gccaggccag caccctcata gataggccag 1650

 caccacactt tgagcgcact tctagtaaac gggtctccag gagtctagat 1700

 ggagctccga ttggtgtcat ggaccaaagt cttatgaagg attttcctgg 1750

 cgctgctggg gagatttcag cctatggacc tggacttgtc agcattgccg 1800

 tggtacaaga tggggacggc aggagggaag tgagaagccc aactaaagcc 1850

 ccacatttgc agctcattga aggaaagaaa aattccttga gagtagaagg 1900

 ggataatatt tatgtcagac atagcaattt aatgttggag gaactggata 1950

 aggcccagga ggacatactg aaacatcagg ctagcattag tgaactcaag 2000

 cgcaatttta tggaatccac acctgagccg cgccctaatg aatgggaaaa 2050

 acgacgtatc acacctctgt ccctacagac acaagggagt tcacatgaga 2100

 ctctgaatat agtggaggag aagaagcggg cagaggttgg gaaagacgaa 2150

 agagtaatca cagaagaaat gaatggtaaa gagatatcac ctgggagtgg 2200

 tcctggggag attcgtaagg tggagcctgt gacacaaaaa gactccacct 2250

 ccctgtcttc tgagagcagc agcagcagca gtgagagtga ggaggaagac 2300

 gtgggagagt accgtcccca ccaccgagtg accgagggca ccatcaggga 2350

 ggaacaggag tatgaagaag aggtggagga agaaccccgc ccggcagcca 2400

 aggtagtaga gagggaggaa gcagtgcccg aagccagccc agtcacacaa 2450

 gcaggtgcca gtgtaatcac agtagaaaca gtgatccagg aaaatgtagg 2500

 tgcccaaaag atacccggag agaagagtgt acacgaaggc gctcttaagc 2550

 aagacatggg agaagaagca gaggaagagc cacagaaagt taacggagag 2600

 gtgtcccatg ttgacattga tgttttgcca caaattattt gttgttcaga 2650

 gccaccagtg gtaaaaacag agatggtaac aatttctgat gcctcacaaa 2700

 ggacagaaat ctccaccaag gaagtcccca ttgtccaaac tgagaccaaa 2750

 accatcacat atgagtctcc acagattgat ggcggggctg gtggtgattc 2800

 gggcacgtta ctgaccgcac aaaccatcac atctgagtcc gtgtcaacaa 2850

 cgacaaccac acacatcacc aagactgtaa aaggtggaat ttctgaaaca 2900

 agaattgaga aacgcattgt gatcacagga gatggagata ttgatcatga 2950

 ccaggcactg gctcaggcga tcagggaagc cagagagcag caccctgaca 3000

 tgtcggtcac aagagtggtg gtacacaaag aaacagagtt ggctgaggaa 3050

 ggggaagatt aagtaagaaa gtcatttttt aaacaacact caactttgtg 3100

 aacccctgaa gattttttga ccgttccaag tcttaatgcc acaccactat 3150

 tccagcgaat ttatgctaca actggtaaca atgaccagaa gcctgaagaa 3200

 ttaaaatgcc aacaccaaac ctttccttac cagctctggt ctatattgct 3250

 cccatgcatt taatatatta ttttgtttta taaccacttc taaatattct 3300

 cagttctttc tttttgttgt tgttaattaa ggggttttgg ttttgttttc 3350

 tgtttacttt gtgtgcaact acctgctttt aatgactcac tttgatcaaa 3400

 tgacagtgaa caaagccagc ccaagctggt aaggtgctgt tcacttgaac 3450

 aggtgctgtt gcgcagaaag gaaactctgt gactaattta gatagtggct 3500

 ttccttcttc tggattcttt tcattgaatt ctcacagtaa atatttacgg 3550

 agttttcaaa ttgcagcaaa tatactgtat gagaaaatat taatacagat 3600

 taaaagcctt tcttacatct tgaaaatttt ctaatatttg agaatttcac 3650

 agggatgttt tttatattgg gacccttttg actttccagt cctgtgactt 3700

 tctactttta gtagagagtc agaatctctg gactggagaa taatgaagaa 3750

 gttcactgac tgtgcactgt gcttagagac cctgccgcac cacagtgcca 3800

 atgcttgtca gacacatgcc cttcggcagc attccagaac aggagggaag 3850

 agaaagagaa aactttcttc cctctactaa aagattcagg cagcttaaaa 3900

 ccttagtgct ttctttctta acatacccaa atttcaattc tttccattat 3950

 ttgaacactt gggtagaact cttgctttgt attaaacctc tttgtctaca 4000

 catgtaaaac ttaccttttg ttattgagca ggcctatctc tttcagatag 4050

 ttttatgatt cacacaggtt tgaggatgct ggggagaggg ggagggggct 4100

 gtggtggtgt tctgttggtt acaagaaagt tataccattt aaagctggca 4150

 ccagagaccc gatagggact tattaactat attgaacatt ttttcctttg 4200

 cctttgaccc tatgtatagt tacgatgcca gattagattt atagcagcct 4250

 caagttgtat taaatgatat tttgcttcct gtaatactat tataaaataa 4300

 agtttgttta ttctctaaaa aaaaaaaaaa aaaaaa 4336

<210> 432
<211> 1005
<212> PRT
<213> Homo sapien

<400> 432
 Met Thr Thr Glu Val Gly Ser Val Ser Glu Val Lys Lys Asp Ser
   1               5                  10                  15

 Ser Gln Leu Gly Thr Asp Ala Thr Lys Glu Lys Pro Lys Glu Val
                  20                  25                  30

 Ala Glu Asn Gln Gln Asn Gln Ser Ser Asp Pro Glu Glu Glu Lys
                  35                  40                  45

 Gly Ser Gln Pro Pro Pro Ala Ala Glu Ser Gln Ser Ser Leu Arg
                  50                  55                  60

 Arg Gln Lys Arg Glu Lys Glu Thr Ser Glu Ser Arg Gly Ile Ser
                  65                  70                  75

 Arg Phe Ile Pro Pro Trp Leu Lys Lys Gln Lys Ser Tyr Thr Leu
                  80                  85                  90

 Val Val Ala Lys Asp Gly Gly Asp Lys Lys Glu Pro Thr Gln Ala
                  95                 100                 105

 Val Val Glu Glu Gln Val Leu Asp Lys Glu Glu Pro Leu Pro Glu
                 110                 115                 120

 Glu Gln Arg Gln Ala Lys Gly Asp Ala Glu Glu Met Ala Gln Lys
                 125                 130                 135

 Lys Gln Glu Ile Lys Val Glu Val Lys Glu Glu Lys Pro Ser Val
                 140                 145                 150

 Ser Lys Glu Glu Lys Pro Ser Val Ser Lys Val Glu Met Gln Pro
                 155                 160                 165

 Thr Glu Leu Val Ser Lys Glu Arg Glu Glu Lys Val Lys Glu Thr
                 170                 175                 180

 Gln Glu Asp Lys Leu Glu Gly Gly Ala Ala Lys Arg Glu Thr Lys
                 185                 190                 195

 Glu Val Gln Thr Asn Glu Leu Lys Ala Glu Lys Ala Ser Gln Lys
                 200                 205                 210

 Val Thr Lys Lys Thr Lys Thr Val Gln Cys Lys Val Thr Leu Leu
                 215                 220                 225

 Asp Gly Thr Glu Tyr Ser Cys Asp Leu Glu Lys His Ala Lys Gly
                 230                 235                 240

 Gln Val Leu Phe Asp Lys Val Cys Glu His Leu Asn Leu Leu Glu
                 245                 250                 255

 Lys Asp Tyr Phe Gly Leu Leu Phe Gln Glu Ser Pro Glu Gln Lys
                 260                 265                 270

 Asn Trp Leu Asp Pro Ala Lys Glu Ile Lys Arg Gln Leu Arg Asn
                 275                 280                 285

 Leu Pro Trp Leu Phe Thr Phe Asn Val Lys Phe Tyr Pro Pro Asp
                 290                 295                 300

 Pro Ser Gln Leu Thr Glu Asp Ile Thr Arg Tyr Phe Leu Cys Leu
                 305                 310                 315

 Gln Leu Arg Gln Asp Ile Ala Ser Gly Arg Leu Pro Cys Ser Phe
                 320                 325                 330

 Val Thr His Ala Leu Leu Gly Ser Tyr Thr Leu Gln Ala Glu Leu
                 335                 340                 345

 Gly Asp Tyr Asp Pro Glu Glu His Gly Ser Ile Asp Leu Ser Glu
                 350                 355                 360

 Phe Gln Phe Ala Pro Thr Gln Thr Lys Glu Leu Glu Glu Lys Val
                 365                 370                 375

 Ala Glu Leu His Lys Thr His Arg Gly Leu Ser Pro Ala Gln Ala
                 380                 385                 390

 Asp Ser Gln Phe Leu Glu Asn Ala Lys Arg Leu Ser Met Tyr Gly
                 395                 400                 405

 Val Asp Leu His His Ala Lys Asp Ser Glu Gly Val Asp Ile Lys
                 410                 415                 420

 Leu Gly Val Cys Ala Asn Gly Leu Leu Ile Tyr Lys Asp Arg Leu
                 425                 430                 435

 Arg Ile Asn Arg Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr
                 440                 445                 450

 Lys Arg Ser Asn Phe Tyr Ile Lys Val Arg Pro Ala Glu Leu Glu
                 455                 460                 465

 Gln Phe Glu Ser Thr Ile Gly Phe Lys Leu Pro Asn His Arg Ala
                 470                 475                 480

 Ala Lys Arg Leu Trp Lys Val Cys Val Glu His His Thr Phe Tyr
                 485                 490                 495

 Arg Leu Val Ser Pro Glu Gln Pro Pro Lys Ala Lys Phe Leu Thr
                 500                 505                 510

 Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln Ala Gln Thr
                 515                 520                 525

 Arg Gln Ala Ser Thr Leu Ile Asp Arg Pro Ala Pro His Phe Glu
                 530                 535                 540

 Arg Thr Ser Ser Lys Arg Val Ser Arg Ser Leu Asp Gly Ala Pro
                 545                 550                 555

 Ile Gly Val Met Asp Gln Ser Leu Met Lys Asp Phe Pro Gly Ala
                 560                 565                 570

 Ala Gly Glu Ile Ser Ala Tyr Gly Pro Gly Leu Val Ser Ile Ala
                 575                 580                 585

 Val Val Gln Asp Gly Asp Gly Arg Arg Glu Val Arg Ser Pro Thr
                 590                 595                 600

 Lys Ala Pro His Leu Gln Leu Ile Glu Gly Lys Lys Asn Ser Leu
                 605                 610                 615

 Arg Val Glu Gly Asp Asn Ile Tyr Val Arg His Ser Asn Leu Met
                 620                 625                 630

 Leu Glu Glu Leu Asp Lys Ala Gln Glu Asp Ile Leu Lys His Gln
                 635                 640                 645

 Ala Ser Ile Ser Glu Leu Lys Arg Asn Phe Met Glu Ser Thr Pro
                 650                 655                 660

 Glu Pro Arg Pro Asn Glu Trp Glu Lys Arg Arg Ile Thr Pro Leu
                 665                 670                 675

 Ser Leu Gln Thr Gln Gly Ser Ser His Glu Thr Leu Asn Ile Val
                 680                 685                 690

 Glu Glu Lys Lys Arg Ala Glu Val Gly Lys Asp Glu Arg Val Ile
                 695                 700                 705

 Thr Glu Glu Met Asn Gly Lys Glu Ile Ser Pro Gly Ser Gly Pro
                 710                 715                 720

 Gly Glu Ile Arg Lys Val Glu Pro Val Thr Gln Lys Asp Ser Thr
                 725                 730                 735

 Ser Leu Ser Ser Glu Ser Ser Ser Ser Ser Ser Glu Ser Glu Glu
                 740                 745                 750

 Glu Asp Val Gly Glu Tyr Arg Pro His His Arg Val Thr Glu Gly
                 755                 760                 765

 Thr Ile Arg Glu Glu Gln Glu Tyr Glu Glu Glu Val Glu Glu Glu
                 770                 775                 780

 Pro Arg Pro Ala Ala Lys Val Val Glu Arg Glu Glu Ala Val Pro
                 785                 790                 795

 Glu Ala Ser Pro Val Thr Gln Ala Gly Ala Ser Val Ile Thr Val
                 800                 805                 810

 Glu Thr Val Ile Gln Glu Asn Val Gly Ala Gln Lys Ile Pro Gly
                 815                 820                 825

 Glu Lys Ser Val His Glu Gly Ala Leu Lys Gln Asp Met Gly Glu
                 830                 835                 840

 Glu Ala Glu Glu Glu Pro Gln Lys Val Asn Gly Glu Val Ser His
                 845                 850                 855

 Val Asp Ile Asp Val Leu Pro Gln Ile Ile Cys Cys Ser Glu Pro
                 860                 865                 870

 Pro Val Val Lys Thr Glu Met Val Thr Ile Ser Asp Ala Ser Gln
                 875                 880                 885

 Arg Thr Glu Ile Ser Thr Lys Glu Val Pro Ile Val Gln Thr Glu
                 890                 895                 900

 Thr Lys Thr Ile Thr Tyr Glu Ser Pro Gln Ile Asp Gly Gly Ala
                 905                 910                 915

 Gly Gly Asp Ser Gly Thr Leu Leu Thr Ala Gln Thr Ile Thr Ser
                 920                 925                 930

 Glu Ser Val Ser Thr Thr Thr Thr Thr His Ile Thr Lys Thr Val
                 935                 940                 945

 Lys Gly Gly Ile Ser Glu Thr Arg Ile Glu Lys Arg Ile Val Ile
                 950                 955                 960

 Thr Gly Asp Gly Asp Ile Asp His Asp Gln Ala Leu Ala Gln Ala
                 965                 970                 975

 Ile Arg Glu Ala Arg Glu Gln His Pro Asp Met Ser Val Thr Arg
                 980                 985                 990

 Val Val Val His Lys Glu Thr Glu Leu Ala Glu Glu Gly Glu Asp
                 995                1000                1005

<210> 433
<211> 4336
<212> DNA
<213> Homo sapien

<400> 433
 ggcgggtccc gcggcgaggc agctcctggg cataagctgt ggccatgact 50

 actgaagtag gctctgtgtc tgaagtgaag aaggactcta gccagttagg 100

 aacagatgca accaaggaaa aacctaaaga agtagcagaa aatcagcaga 150

 atcagtcttc cgatccagag gaggaaaaag gttcccagcc acctcctgca 200

 gctgaaagcc aaagtagtct acgccgccag aagagagaga aggaaacatc 250

 ggagagcagg ggtatttctc ggttcatacc gccatggctt aagaagcaaa 300

 agtcatatac cttagtagtg gccaaagatg gaggagataa aaaagagcct 350

 acccaagctg ttgttgaaga acaggtctta gataaagagg aaccccttcc 400

 agaagaacag agacaggcta agggtgatgc tgaagaaatg gctcagaaga 450

 aacaagagat taaagttgaa gtcaaggaag aaaaaccctc agtgagcaag 500

 gaagaaaaac cctcagtgag caaagtggag atgcagccta ctgaattagt 550

 aagtaaggag agagaagaga aggtaaaaga aacacaggaa gacaaattag 600

 aaggaggagc agcaaaaagg gagaccaagg aagtgcagac caatgagctg 650

 aaagcagaga aggcatctca aaaagtcacc aagaagacca aaactgtcca 700

 gtgtaaagtg accctcttag atggcaccga atacagctgt gacctggaga 750

 aacatgccaa gggacaagtg ttatttgaca aagtgtgtga acacctcaat 800

 ctcttggaga aagactactt tggacttttg tttcaggaaa gccctgagca 850

 gaaaaactgg ttagatcctg ctaaagaaat aaagagacaa ctgagaaacc 900

 ttccatggct attcactttt aatgtgaagt tttatcctcc tgatccttct 950

 caattgactg aagatatcac cagatacttc ttgtgccttc agctccggca 1000

 ggacattgcc tctggccgcc tgccctgctc ttttgtgact catgctctcc 1050

 tgggatccta caccctgcag gctgaacttg gtgactatga cccagaagaa 1100

 catggcagca tcgacctcag tgaattccag tttgccccta ctcagactaa 1150

 ggagctggaa gagaaggtgg cagagctgca caaaacccac aggggcttat 1200

 cgccagcaca agctgattcc cagttcttag aaaatgcaaa gaggctttcc 1250

 atgtatggtg ttgacctaca tcatgccaag gactcagaag gtgtggacat 1300

 caagctgggc gtgtgtgcta atggacttct catttacaaa gacagactgc 1350

 gaatcaatcg ttttgcttgg ccgaaaatct taaaaatttc ctataaacgc 1400

 agtaacttct acattaaagt cagaccggca gagctggaac agtttgagag 1450

 taccattgga ttcaaactgc caaaccaccg ggcagcgaaa agactatgga 1500

 aagtgtgcgt ggagcatcat actttctaca ggcttgtttc tccagagcag 1550

 ccaccaaaag ccaagttcct gaccttgggg tccaaatttc gctatagtgg 1600

 ccgcacccaa gcacagaccc gccaggccag caccctcata gataggccag 1650

 caccacactt tgagcgcact tctagtaaac gggtctccag gagtctagat 1700

 ggagctccga ttggtgtcat ggaccaaagt cttatgaagg attttcctgg 1750

 cgctgctggg gagatttcag cctatggacc tggacttgtc agcattgccg 1800

 tggtacaaga tggggacggc aggagggaag tgagaagccc aactaaagcc 1850

 ccacatttgc agctcattga aggaaagaaa aattccttga gagtagaagg 1900

 ggataatatt tatgtcagac atagcaattt aatgttggag gaactggata 1950

 aggcccagga ggacatactg aaacatcagg ctagcattag tgaactcaag 2000

 cgcaatttta tggaatccac acctgagccg cgccctaatg aatgggaaaa 2050

 acgacgtatc acacctctgt ccctacagac acaagggagt tcacatgaga 2100

 ctctgaatat agtggaggag aagaagcggg cagaggttgg gaaagacgaa 2150

 agagtaatca cagaagaaat gaatggtaaa gagatatcac ctgggagtgg 2200

 tcctggggag attcgtaagg tggagcctgt gacacaaaaa gactccacct 2250

 ccctgtcttc tgagagcagc agcagcagca gtgagagtga ggaggaagac 2300

 gtgggagagt accgtcccca ccaccgagtg accgagggca ccatcaggga 2350

 ggaacaggag tatgaagaag aggtggagga agaaccccgc ccggcagcca 2400

 aggtagtaga gagggaggaa gcagtgcccg aagccagccc agtcacacaa 2450

 gcaggtgcca gtgtaatcac agtagaaaca gtgatccagg aaaatgtagg 2500

 tgcccaaaag atacccggag agaagagtgt acacgaaggc gctcttaagc 2550

 aagacatggg agaagaagca gaggaagagc cacagaaagt taacggagag 2600

 gtgtcccatg ttgacattga tgttttgcca caaattattt gttgttcaga 2650

 gccaccagtg gtaaaaacag agatggtaac aatttctgat gcctcacaaa 2700

 ggacagaaat ctccaccaag gaagtcccca ttgtccaaac tgagaccaaa 2750

 accatcacat atgagtctcc acagattgat ggcggggctg gtggtgattc 2800

 gggcacgtta ctgaccgcac aaaccatcac atctgagtcc gtgtcaacaa 2850

 cgacaaccac acacatcacc aagactgtaa aaggtggaat ttctgaaaca 2900

 agaattgaga aacgcattgt gatcacagga gatggagata ttgatcatga 2950

 ccaggcactg gctcaggcga tcagggaagc cagagagcag caccctgaca 3000

 tgtcggtcac aagagtggtg gtacacaaag aaacagagtt ggctgaggaa 3050

 ggggaagatt aagtaagaaa gtcatttttt aaacaacact caactttgtg 3100

 aacccctgaa gattttttga ccgttccaag tcttaatgcc acaccactat 3150

 tccagcgaat ttatgctaca actggtaaca atgaccagaa gcctgaagaa 3200

 ttaaaatgcc aacaccaaac ctttccttac cagctctggt ctatattgct 3250

 cccatgcatt taatatatta ttttgtttta taaccacttc taaatattct 3300

 cagttctttc tttttgttgt tgttaattaa ggggttttgg ttttgttttc 3350

 tgtttacttt gtgtgcaact acctgctttt aatgactcac tttgatcaaa 3400

 tgacagtgaa caaagccagc ccaagctggt aaggtgctgt tcacttgaac 3450

 aggtgctgtt gcgcagaaag gaaactctgt gactaattta gatagtggct 3500

 ttccttcttc tggattcttt tcattgaatt ctcacagtaa atatttacgg 3550

 agttttcaaa ttgcagcaaa tatactgtat gagaaaatat taatacagat 3600

 taaaagcctt tcttacatct tgaaaatttt ctaatatttg agaatttcac 3650

 agggatgttt tttatattgg gacccttttg actttccagt cctgtgactt 3700

 tctactttta gtagagagtc agaatctctg gactggagaa taatgaagaa 3750

 gttcactgac tgtgcactgt gcttagagac cctgccgcac cacagtgcca 3800

 atgcttgtca gacacatgcc cttcggcagc attccagaac aggagggaag 3850

 agaaagagaa aactttcttc cctctactaa aagattcagg cagcttaaaa 3900

 ccttagtgct ttctttctta acatacccaa atttcaattc tttccattat 3950

 ttgaacactt gggtagaact cttgctttgt attaaacctc tttgtctaca 4000

 catgtaaaac ttaccttttg ttattgagca ggcctatctc tttcagatag 4050

 ttttatgatt cacacaggtt tgaggatgct ggggagaggg ggagggggct 4100

 gtggtggtgt tctgttggtt acaagaaagt tataccattt aaagctggca 4150

 ccagagaccc gatagggact tattaactat attgaacatt ttttcctttg 4200

 cctttgaccc tatgtatagt tacgatgcca gattagattt atagcagcct 4250

 caagttgtat taaatgatat tttgcttcct gtaatactat tataaaataa 4300

 agtttgttta ttctctaaaa aaaaaaaaaa aaaaaa 4336

<210> 434
<211> 1005
<212> PRT
<213> Homo sapien

<400> 434
 Met Thr Thr Glu Val Gly Ser Val Ser Glu Val Lys Lys Asp Ser
   1               5                  10                  15

 Ser Gln Leu Gly Thr Asp Ala Thr Lys Glu Lys Pro Lys Glu Val
                  20                  25                  30

 Ala Glu Asn Gln Gln Asn Gln Ser Ser Asp Pro Glu Glu Glu Lys
                  35                  40                  45

 Gly Ser Gln Pro Pro Pro Ala Ala Glu Ser Gln Ser Ser Leu Arg
                  50                  55                  60

 Arg Gln Lys Arg Glu Lys Glu Thr Ser Glu Ser Arg Gly Ile Ser
                  65                  70                  75

 Arg Phe Ile Pro Pro Trp Leu Lys Lys Gln Lys Ser Tyr Thr Leu
                  80                  85                  90

 Val Val Ala Lys Asp Gly Gly Asp Lys Lys Glu Pro Thr Gln Ala
                  95                 100                 105

 Val Val Glu Glu Gln Val Leu Asp Lys Glu Glu Pro Leu Pro Glu
                 110                 115                 120

 Glu Gln Arg Gln Ala Lys Gly Asp Ala Glu Glu Met Ala Gln Lys
                 125                 130                 135

 Lys Gln Glu Ile Lys Val Glu Val Lys Glu Glu Lys Pro Ser Val
                 140                 145                 150

 Ser Lys Glu Glu Lys Pro Ser Val Ser Lys Val Glu Met Gln Pro
                 155                 160                 165

 Thr Glu Leu Val Ser Lys Glu Arg Glu Glu Lys Val Lys Glu Thr
                 170                 175                 180

 Gln Glu Asp Lys Leu Glu Gly Gly Ala Ala Lys Arg Glu Thr Lys
                 185                 190                 195

 Glu Val Gln Thr Asn Glu Leu Lys Ala Glu Lys Ala Ser Gln Lys
                 200                 205                 210

 Val Thr Lys Lys Thr Lys Thr Val Gln Cys Lys Val Thr Leu Leu
                 215                 220                 225

 Asp Gly Thr Glu Tyr Ser Cys Asp Leu Glu Lys His Ala Lys Gly
                 230                 235                 240

 Gln Val Leu Phe Asp Lys Val Cys Glu His Leu Asn Leu Leu Glu
                 245                 250                 255

 Lys Asp Tyr Phe Gly Leu Leu Phe Gln Glu Ser Pro Glu Gln Lys
                 260                 265                 270

 Asn Trp Leu Asp Pro Ala Lys Glu Ile Lys Arg Gln Leu Arg Asn
                 275                 280                 285

 Leu Pro Trp Leu Phe Thr Phe Asn Val Lys Phe Tyr Pro Pro Asp
                 290                 295                 300

 Pro Ser Gln Leu Thr Glu Asp Ile Thr Arg Tyr Phe Leu Cys Leu
                 305                 310                 315

 Gln Leu Arg Gln Asp Ile Ala Ser Gly Arg Leu Pro Cys Ser Phe
                 320                 325                 330

 Val Thr His Ala Leu Leu Gly Ser Tyr Thr Leu Gln Ala Glu Leu
                 335                 340                 345

 Gly Asp Tyr Asp Pro Glu Glu His Gly Ser Ile Asp Leu Ser Glu
                 350                 355                 360

 Phe Gln Phe Ala Pro Thr Gln Thr Lys Glu Leu Glu Glu Lys Val
                 365                 370                 375

 Ala Glu Leu His Lys Thr His Arg Gly Leu Ser Pro Ala Gln Ala
                 380                 385                 390

 Asp Ser Gln Phe Leu Glu Asn Ala Lys Arg Leu Ser Met Tyr Gly
                 395                 400                 405

 Val Asp Leu His His Ala Lys Asp Ser Glu Gly Val Asp Ile Lys
                 410                 415                 420

 Leu Gly Val Cys Ala Asn Gly Leu Leu Ile Tyr Lys Asp Arg Leu
                 425                 430                 435

 Arg Ile Asn Arg Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr
                 440                 445                 450

 Lys Arg Ser Asn Phe Tyr Ile Lys Val Arg Pro Ala Glu Leu Glu
                 455                 460                 465

 Gln Phe Glu Ser Thr Ile Gly Phe Lys Leu Pro Asn His Arg Ala
                 470                 475                 480

 Ala Lys Arg Leu Trp Lys Val Cys Val Glu His His Thr Phe Tyr
                 485                 490                 495

 Arg Leu Val Ser Pro Glu Gln Pro Pro Lys Ala Lys Phe Leu Thr
                 500                 505                 510

 Leu Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln Ala Gln Thr
                 515                 520                 525

 Arg Gln Ala Ser Thr Leu Ile Asp Arg Pro Ala Pro His Phe Glu
                 530                 535                 540

 Arg Thr Ser Ser Lys Arg Val Ser Arg Ser Leu Asp Gly Ala Pro
                 545                 550                 555

 Ile Gly Val Met Asp Gln Ser Leu Met Lys Asp Phe Pro Gly Ala
                 560                 565                 570

 Ala Gly Glu Ile Ser Ala Tyr Gly Pro Gly Leu Val Ser Ile Ala
                 575                 580                 585

 Val Val Gln Asp Gly Asp Gly Arg Arg Glu Val Arg Ser Pro Thr
                 590                 595                 600

 Lys Ala Pro His Leu Gln Leu Ile Glu Gly Lys Lys Asn Ser Leu
                 605                 610                 615

 Arg Val Glu Gly Asp Asn Ile Tyr Val Arg His Ser Asn Leu Met
                 620                 625                 630

 Leu Glu Glu Leu Asp Lys Ala Gln Glu Asp Ile Leu Lys His Gln
                 635                 640                 645

 Ala Ser Ile Ser Glu Leu Lys Arg Asn Phe Met Glu Ser Thr Pro
                 650                 655                 660

 Glu Pro Arg Pro Asn Glu Trp Glu Lys Arg Arg Ile Thr Pro Leu
                 665                 670                 675

 Ser Leu Gln Thr Gln Gly Ser Ser His Glu Thr Leu Asn Ile Val
                 680                 685                 690

 Glu Glu Lys Lys Arg Ala Glu Val Gly Lys Asp Glu Arg Val Ile
                 695                 700                 705

 Thr Glu Glu Met Asn Gly Lys Glu Ile Ser Pro Gly Ser Gly Pro
                 710                 715                 720

 Gly Glu Ile Arg Lys Val Glu Pro Val Thr Gln Lys Asp Ser Thr
                 725                 730                 735

 Ser Leu Ser Ser Glu Ser Ser Ser Ser Ser Ser Glu Ser Glu Glu
                 740                 745                 750

 Glu Asp Val Gly Glu Tyr Arg Pro His His Arg Val Thr Glu Gly
                 755                 760                 765

 Thr Ile Arg Glu Glu Gln Glu Tyr Glu Glu Glu Val Glu Glu Glu
                 770                 775                 780

 Pro Arg Pro Ala Ala Lys Val Val Glu Arg Glu Glu Ala Val Pro
                 785                 790                 795

 Glu Ala Ser Pro Val Thr Gln Ala Gly Ala Ser Val Ile Thr Val
                 800                 805                 810

 Glu Thr Val Ile Gln Glu Asn Val Gly Ala Gln Lys Ile Pro Gly
                 815                 820                 825

 Glu Lys Ser Val His Glu Gly Ala Leu Lys Gln Asp Met Gly Glu
                 830                 835                 840

 Glu Ala Glu Glu Glu Pro Gln Lys Val Asn Gly Glu Val Ser His
                 845                 850                 855

 Val Asp Ile Asp Val Leu Pro Gln Ile Ile Cys Cys Ser Glu Pro
                 860                 865                 870

 Pro Val Val Lys Thr Glu Met Val Thr Ile Ser Asp Ala Ser Gln
                 875                 880                 885

 Arg Thr Glu Ile Ser Thr Lys Glu Val Pro Ile Val Gln Thr Glu
                 890                 895                 900

 Thr Lys Thr Ile Thr Tyr Glu Ser Pro Gln Ile Asp Gly Gly Ala
                 905                 910                 915

 Gly Gly Asp Ser Gly Thr Leu Leu Thr Ala Gln Thr Ile Thr Ser
                 920                 925                 930

 Glu Ser Val Ser Thr Thr Thr Thr Thr His Ile Thr Lys Thr Val
                 935                 940                 945

 Lys Gly Gly Ile Ser Glu Thr Arg Ile Glu Lys Arg Ile Val Ile
                 950                 955                 960

 Thr Gly Asp Gly Asp Ile Asp His Asp Gln Ala Leu Ala Gln Ala
                 965                 970                 975

 Ile Arg Glu Ala Arg Glu Gln His Pro Asp Met Ser Val Thr Arg
                 980                 985                 990

 Val Val Val His Lys Glu Thr Glu Leu Ala Glu Glu Gly Glu Asp
                 995                1000                1005

<210> 435
<211> 1542
<212> DNA
<213> Homo sapien

<400> 435
 tgcgtttagg gcgaagacgg agttgtaaac ttcttaaaat tcctctctcg 50

 acacttcggt aattcctctt tcgagactaa agctcttttt gtatgcgtgt 100

 gtgtcaagcg tatgccccgg gattctcctc cgcttccttt tctcggtctt 150

 ccttcttgct ttagggaccg gaagagtcct tgaaccaaaa tagctcggcg 200

 ggcacttccg gggccggcgc ccagagttcc gggagggtgc aggcaggaga 250

 gggaaaggca gcagcggcgg cagctggagg atgaagaagg agcatgtgct 300

 tcactgccag ttctccgcgt ggtacccgtt cttccgaggc gttaccatca 350

 agagtgtcat tcttccactt cctcagaatg tgaaggatta tttactcgat 400

 gatggaactc tggtggtttc aggaagggat gatccaccaa cacattctca 450

 gccagacagt gatgatgaag cagaagaaat acagtggtct gatgatgaga 500

 acacagccac gcttacggca ccagaatttc ctgagtttgc cactaaagtc 550

 caggaaccta tcaattccct cgggggcagt gtctttccta agcttaattg 600

 gagtgcccca agggatgcgt attggatagc aatgaatagt tctctgaaat 650

 gtaaaaccct cagcgacatc tttctgcttt tcaagagttc cgatttcatc 700

 actcgtgact tcactcagcc gtttattcat tgtactgatg attctccaga 750

 tccatgtata gaatatgagc tcgttctccg aaaatggtgt gaattgattc 800

 ctggggctga gtttcgatgt tttgtcaagg aaaacaagct tattggtatt 850

 tctcaaagag actacacaca atactatgat catatttcta aacaaaagga 900

 agaaattcgc agatgcatac aagacttttt caagaaacac atacagtaca 950

 aattcttaga tgaagacttt gtgttcgata tatacagaga cagtaggggg 1000

 aaggtgtggc tcattgactt taatccattt ggtgaagtca cagattcact 1050

 gctgttcacc tgggaagaac tgatatctga gaacaactta aacggcgatt 1100

 ttagtgaagt tgacgctcaa gagcaggatt ccccagcttt ccgttgcaca 1150

 aacagtgaag tgacagtcca gcccagcccc tatttgagtt accggctacc 1200

 caaggacttt gtagacctct ctactgggag ggacgctcac aagctaatag 1250

 acttccttaa gctgaagaga aatcagcagg aggacgactg atgagcgtac 1300

 tgtaactgga gaagaggagg ccccgcccca ccgctccggg agctgctcat 1350

 cagccgcaac ttcctgccga ccctgatgcg ggtgggccga gcagtgtgga 1400

 catcagccac tttttatatt catgtacatt cacctgggga aaaaaacgga 1450

 gggactttgc tacttgtaaa aataacataa taaatagatc ttaaacatag 1500

 gaaaaccata ctgttctgat aataaaatgc tttctatgaa at 1542

<210> 436
<211> 336
<212> PRT
<213> Homo sapien

<400> 436
 Met Lys Lys Glu His Val Leu His Cys Gln Phe Ser Ala Trp Tyr
   1               5                  10                  15

 Pro Phe Phe Arg Gly Val Thr Ile Lys Ser Val Ile Leu Pro Leu
                  20                  25                  30

 Pro Gln Asn Val Lys Asp Tyr Leu Leu Asp Asp Gly Thr Leu Val
                  35                  40                  45

 Val Ser Gly Arg Asp Asp Pro Pro Thr His Ser Gln Pro Asp Ser
                  50                  55                  60

 Asp Asp Glu Ala Glu Glu Ile Gln Trp Ser Asp Asp Glu Asn Thr
                  65                  70                  75

 Ala Thr Leu Thr Ala Pro Glu Phe Pro Glu Phe Ala Thr Lys Val
                  80                  85                  90

 Gln Glu Pro Ile Asn Ser Leu Gly Gly Ser Val Phe Pro Lys Leu
                  95                 100                 105

 Asn Trp Ser Ala Pro Arg Asp Ala Tyr Trp Ile Ala Met Asn Ser
                 110                 115                 120

 Ser Leu Lys Cys Lys Thr Leu Ser Asp Ile Phe Leu Leu Phe Lys
                 125                 130                 135

 Ser Ser Asp Phe Ile Thr Arg Asp Phe Thr Gln Pro Phe Ile His
                 140                 145                 150

 Cys Thr Asp Asp Ser Pro Asp Pro Cys Ile Glu Tyr Glu Leu Val
                 155                 160                 165

 Leu Arg Lys Trp Cys Glu Leu Ile Pro Gly Ala Glu Phe Arg Cys
                 170                 175                 180

 Phe Val Lys Glu Asn Lys Leu Ile Gly Ile Ser Gln Arg Asp Tyr
                 185                 190                 195

 Thr Gln Tyr Tyr Asp His Ile Ser Lys Gln Lys Glu Glu Ile Arg
                 200                 205                 210

 Arg Cys Ile Gln Asp Phe Phe Lys Lys His Ile Gln Tyr Lys Phe
                 215                 220                 225

 Leu Asp Glu Asp Phe Val Phe Asp Ile Tyr Arg Asp Ser Arg Gly
                 230                 235                 240

 Lys Val Trp Leu Ile Asp Phe Asn Pro Phe Gly Glu Val Thr Asp
                 245                 250                 255

 Ser Leu Leu Phe Thr Trp Glu Glu Leu Ile Ser Glu Asn Asn Leu
                 260                 265                 270

 Asn Gly Asp Phe Ser Glu Val Asp Ala Gln Glu Gln Asp Ser Pro
                 275                 280                 285

 Ala Phe Arg Cys Thr Asn Ser Glu Val Thr Val Gln Pro Ser Pro
                 290                 295                 300

 Tyr Leu Ser Tyr Arg Leu Pro Lys Asp Phe Val Asp Leu Ser Thr
                 305                 310                 315

 Gly Arg Asp Ala His Lys Leu Ile Asp Phe Leu Lys Leu Lys Arg
                 320                 325                 330

 Asn Gln Gln Glu Asp Asp
                 335

<210> 437
<211> 2386
<212> DNA
<213> Homo sapien

<400> 437
 agcatacgcc gagccggtct ttgagcgcta acgtctttct gtctccccgc 50

 ggtggtgatg acggtgaaaa ctgaggctgc taagggcacc ctcacttact 100

 ccaggatgag gggcatggtg gcaattctca tcgctttcat gaagcagagg 150

 aggatgggtc tgaacgactt tattcagaag attgccaata actcctatgc 200

 atgcaaacac cctgaagttc agtccatctt gaagatctcc caacctcagg 250

 agcctgagct tatgaatgcc aacccttctc ctccaccaag tccttctcag 300

 caaatcaacc ttggcccgtc gtccaatcct catgctaaac catctgactt 350

 tcacttcttg aaagtgatcg gaaagggcag ttttggaaag gttcttctag 400

 caagacacaa ggcagaagaa gtgttctatg cagtcaaagt tttacagaag 450

 aaagcaatcc tgaaaaagaa agaggagaag catattatgt cggagcggaa 500

 tgttctgttg aagaatgtga agcacccttt cctggtgggc cttcacttct 550

 ctttccagac tgctgacaaa ttgtactttg tcctagacta cattaatggt 600

 ggagagttgt tctaccatct ccagagggaa cgctgcttcc tggaaccacg 650

 ggctcgtttc tatgctgctg aaatagccag tgccttgggc tacctgcatt 700

 cactgaacat cgtttataga gacttaaaac cagagaatat tttgctagat 750

 tcacagggac acattgtcct tactgacttc ggactctgca aggagaacat 800

 tgaacacaac agcacaacat ccaccttctg tggcacgccg gagtatctcg 850

 cacctgaggt gcttcataag cagccttatg acaggactgt ggactggtgg 900

 tgcctgggag ctgtcttgta tgagatgctg tatggcctgc cgccttttta 950

 tagccgaaac acagctgaaa tgtacgacaa cattctgaac aagcctctcc 1000

 agctgaaacc aaatattaca aattccgcaa gacacctcct ggagggcctc 1050

 ctgcagaagg acaggacaaa gcggctcggg gccaaggatg acttcatgga 1100

 gattaagagt catgtcttct tctccttaat taactgggat gatctcatta 1150

 ataagaagat tactccccct tttaacccaa atgtgagtgg gcccaacgac 1200

 ctacggcact ttgaccccga gtttaccgaa gagcctgtcc ccaactccat 1250

 tggcaagtcc cctgacagcg tcctcgtcac agccagcgtc aaggaagctg 1300

 ccgaggcttt cctaggcttt tcctatgcgc ctcccacgga ctctttcctc 1350

 tgaaccctgt tagggcttgg ttttaaagga ttttatgtgt gtttccgaat 1400

 gttttagtta gccttttggt ggagccgcca gctgacagga catcttacaa 1450

 gagaatttgc acatctctgg aagcttagca atcttattgc acactgttcg 1500

 ctggaagctt tttgaagagc acattctcct cagtgagctc atgaggtttt 1550

 catttttatt cttccttcca acgtggtgct atctctgaaa cgagcgttag 1600

 agtgccgcct tagacggagg caggagtttc gttagaaagc ggacgctgtt 1650

 ctaaaaaagg tctcctgcag atctgtctgg gctgtgatga cgaatattat 1700

 gaaatgtgcc ttttctgaag agattgtgtt agctccaaag cttttcctat 1750

 cgcagtgttt cagttcttta ttttcccttg tggatatgct gtgtgaaccg 1800

 tcgtgtgagt gtggtatgcc tgatcacaga tggattttgt tataagcatc 1850

 aatgtgacac ttgcaggaca ctacaacgtg ggacattgtt tgtttcttcc 1900

 atatttggaa gataaattta tgtgtagact tttttgtaag atacggttaa 1950

 taactaaaat ttattgaaat ggtcttgcaa tgactcgtat tcagatgctt 2000

 aaagaaagca ttgctgctac aaatatttct atttttagaa agggttttta 2050

 tggaccaatg ccccagttgt cagtcagagc cgttggtgtt tttcattgtt 2100

 taaaatgtca cctgtaaaat gggcattatt tatgtttttt tttttgcatt 2150

 cctgataatt gtatgtattg tataaagaac gtctgtacat tgggttataa 2200

 cactagtata tttaaactta caggcttatt tgtaatgtaa accaccattt 2250

 taatgtactg taattaacat ggttataata cgtacaatcc ttccctcatc 2300

 ccatcacaca actttttttg tgtgtgataa actgattttg gtttgcaata 2350

 aaaccttgaa aaatatttac aaaaaaaaaa aaaaaa 2386

<210> 438
<211> 431
<212> PRT
<213> Homo sapien

<400> 438
 Met Thr Val Lys Thr Glu Ala Ala Lys Gly Thr Leu Thr Tyr Ser
   1               5                  10                  15

 Arg Met Arg Gly Met Val Ala Ile Leu Ile Ala Phe Met Lys Gln
                  20                  25                  30

 Arg Arg Met Gly Leu Asn Asp Phe Ile Gln Lys Ile Ala Asn Asn
                  35                  40                  45

 Ser Tyr Ala Cys Lys His Pro Glu Val Gln Ser Ile Leu Lys Ile
                  50                  55                  60

 Ser Gln Pro Gln Glu Pro Glu Leu Met Asn Ala Asn Pro Ser Pro
                  65                  70                  75

 Pro Pro Ser Pro Ser Gln Gln Ile Asn Leu Gly Pro Ser Ser Asn
                  80                  85                  90

 Pro His Ala Lys Pro Ser Asp Phe His Phe Leu Lys Val Ile Gly
                  95                 100                 105

 Lys Gly Ser Phe Gly Lys Val Leu Leu Ala Arg His Lys Ala Glu
                 110                 115                 120

 Glu Val Phe Tyr Ala Val Lys Val Leu Gln Lys Lys Ala Ile Leu
                 125                 130                 135

 Lys Lys Lys Glu Glu Lys His Ile Met Ser Glu Arg Asn Val Leu
                 140                 145                 150

 Leu Lys Asn Val Lys His Pro Phe Leu Val Gly Leu His Phe Ser
                 155                 160                 165

 Phe Gln Thr Ala Asp Lys Leu Tyr Phe Val Leu Asp Tyr Ile Asn
                 170                 175                 180

 Gly Gly Glu Leu Phe Tyr His Leu Gln Arg Glu Arg Cys Phe Leu
                 185                 190                 195

 Glu Pro Arg Ala Arg Phe Tyr Ala Ala Glu Ile Ala Ser Ala Leu
                 200                 205                 210

 Gly Tyr Leu His Ser Leu Asn Ile Val Tyr Arg Asp Leu Lys Pro
                 215                 220                 225

 Glu Asn Ile Leu Leu Asp Ser Gln Gly His Ile Val Leu Thr Asp
                 230                 235                 240

 Phe Gly Leu Cys Lys Glu Asn Ile Glu His Asn Ser Thr Thr Ser
                 245                 250                 255

 Thr Phe Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val Leu His
                 260                 265                 270

 Lys Gln Pro Tyr Asp Arg Thr Val Asp Trp Trp Cys Leu Gly Ala
                 275                 280                 285

 Val Leu Tyr Glu Met Leu Tyr Gly Leu Pro Pro Phe Tyr Ser Arg
                 290                 295                 300

 Asn Thr Ala Glu Met Tyr Asp Asn Ile Leu Asn Lys Pro Leu Gln
                 305                 310                 315

 Leu Lys Pro Asn Ile Thr Asn Ser Ala Arg His Leu Leu Glu Gly
                 320                 325                 330

 Leu Leu Gln Lys Asp Arg Thr Lys Arg Leu Gly Ala Lys Asp Asp
                 335                 340                 345

 Phe Met Glu Ile Lys Ser His Val Phe Phe Ser Leu Ile Asn Trp
                 350                 355                 360

 Asp Asp Leu Ile Asn Lys Lys Ile Thr Pro Pro Phe Asn Pro Asn
                 365                 370                 375

 Val Ser Gly Pro Asn Asp Leu Arg His Phe Asp Pro Glu Phe Thr
                 380                 385                 390

 Glu Glu Pro Val Pro Asn Ser Ile Gly Lys Ser Pro Asp Ser Val
                 395                 400                 405

 Leu Val Thr Ala Ser Val Lys Glu Ala Ala Glu Ala Phe Leu Gly
                 410                 415                 420

 Phe Ser Tyr Ala Pro Pro Thr Asp Ser Phe Leu
                 425                 430

<210> 439
<211> 2708
<212> DNA
<213> Homo sapien

<400> 439
 ggcctgttct cgagtccgcg cttttcgtca ccgccatgtc gggaggtggt 50

 gtgattcgtg gccccgcagg gaacaacgat tgccgcatct acgtgggtaa 100

 cttacctcca gacatccgaa ccaaggacat tgaggacgtg ttctacaaat 150

 acggcgctat ccgcgacatc gacctcaaga atcgccgcgg gggaccgccc 200

 ttcgccttcg ttgagttcga ggacccgcga gacgcggaag acgcggtgta 250

 tggtcgcgac ggctatgatt acgatgggta ccgtctgcgg gtggagtttc 300

 ctcgaagcgg ccgtggaaca ggccgaggcg gcggcggggg tggaggtggc 350

 ggagctcccc gaggtcgcta tggcccccca tccaggcggt ctgaaaacag 400

 agtggttgtc tctggactgc ctccaagtgg aagttggcag gatttaaagg 450

 atcacatgcg tgaagcaggt gatgtatgtt atgctgatgt ttaccgagat 500

 ggcactggtg tcgtggagtt tgtacggaaa gaagatatga cctatgcagt 550

 tcgaaaactg gataacacta agtttagatc tcatgaggga gaaactgcct 600

 acatccgggt taaagttgat gggcccagaa gtccaagtta tggaagatct 650

 cgatctcgaa gccgtagtcg tagcagaagc cgtagcagaa gcaacagcag 700

 gagtcgcagt tactccccaa ggagaagcag aggatcacca cgctattctc 750

 cccgtcatag cagatctcgc tctcgtacat aagatgattg gtgacacttt 800

 ttgtagaacc catgttgtat acagttttcc tttattcagt acaatctttt 850

 cattttttaa ttcaaactgt tttgttcaga atgggctaaa gtgttgaatt 900

 gcattcttgt aatatcccct tgctcctaac atctacattc ccttcgtgtc 950

 tttgataaat tgtattttaa gtgatgtcat agacaggatt gtttaaattt 1000

 agttaactcc atactcttca gactgtgata ttgtgtaaat gtctatctgc 1050

 cctggtttgt gtgaactggg atgttggggg tgtttgtggt tatcttacct 1100

 ggggaagttc ttatgtttat cttgcttttc atgtgtcttt ctgtagacat 1150

 atctgaagag atggattaag aatgctttgg attaaggatt gtggagcaca 1200

 tttcaatcat tttaggattg tcaaaaggag gattgaggag gatcagatca 1250

 ataatggagg caatggtatg actccaagtg ctattgtcac agatgaaatt 1300

 ggcagtattg accttatact aaaaggcagg ggttaaaaat gattatatac 1350

 attttcctta aaacacttgc aaacatttta ttcagttgtc tttagctaca 1400

 attgctttgc tttttaaacc ttggcaattg tggcaaaatt atattgccca 1450

 ttttgtagca acttattttg ctcccttccc cccatttttg ttttaatagg 1500

 gactaatgtg ggaagaactg gctaatttgt cacagtgctt agttacaact 1550

 gttaatgtgt gacctgctgt tggtgtacat gtgggtacag ggtgttttta 1600

 aatccaacaa gatagagtat aatatcaata ctgctaaatc tgcatgtcct 1650

 ctgtgtgact gatagagcgt tgctatttca tttttttaag acaaaatgaa 1700

 agcaaaatat agagttccaa tgtattggtg tagataatct agttgggaat 1750

 acttttaagt ctcaccttcc cctttaaact aatattcata attggttcat 1800

 atgtttaaaa gactttaatt tacaaattaa attgcaaatg ggagcattag 1850

 atttagtttt agacttaggt gggtagcaat gccagtaaac ttaaattacg 1900

 taacttcttg caaccacgaa acctgtaata cgctgtacag taacaagtgt 1950

 tggcattatc agttgaactg taaatacaaa atgcttcttc caattagtct 2000

 ctatgatgat taagtttcta aaatttatct gaacaccatt cagaaacttg 2050

 ttttggggaa tttgatagtt attgatgtgc atctgttaaa ctgatgacag 2100

 acataactca tcattcccca gaaacctttt ttgattacag tatctaacat 2150

 tttgcctcct cttttttggt tttgctggtt ataaaggttt ggattggaga 2200

 gggctcactg gatcccaatc cttggagctg gatcattgga ttcaaatcat 2250

 aatgtggata ggatagggag gatgaattac caggattcat ggagcgggat 2300

 cagattacca ggaacatagg agtggattcc tgccccaacc aaaccgcatt 2350

 cgtgtggatt tttttattca acttaattgg ctattccaaa gatttttttt 2400

 ttcctatttt tgacgattgg agcccttaag atgcacgatg gaattgtgtt 2450

 ttgcgttttt tggtaaaagg agcaaagcga ggacctggag ataaacgctg 2500

 gagcaatctc cttggaagga ttcagcacga gtagatggta aacatttaaa 2550

 ggggaaaggg ggggtttgtt taaaatagta aatcagtaag tcacttctaa 2600

 atttaaagaa aacaaaattg gagttgaaga ataagtaggt ttccaattgg 2650

 ctattgccgt tttctttgaa aaaataaaca ttttttaaaa aacaaaaaaa 2700

 aaaaaaaa 2708

<210> 440
<211> 248
<212> PRT
<213> Homo sapien

<400> 440
 Met Ser Gly Gly Gly Val Ile Arg Gly Pro Ala Gly Asn Asn Asp
   1               5                  10                  15

 Cys Arg Ile Tyr Val Gly Asn Leu Pro Pro Asp Ile Arg Thr Lys
                  20                  25                  30

 Asp Ile Glu Asp Val Phe Tyr Lys Tyr Gly Ala Ile Arg Asp Ile
                  35                  40                  45

 Asp Leu Lys Asn Arg Arg Gly Gly Pro Pro Phe Ala Phe Val Glu
                  50                  55                  60

 Phe Glu Asp Pro Arg Asp Ala Glu Asp Ala Val Tyr Gly Arg Asp
                  65                  70                  75

 Gly Tyr Asp Tyr Asp Gly Tyr Arg Leu Arg Val Glu Phe Pro Arg
                  80                  85                  90

 Ser Gly Arg Gly Thr Gly Arg Gly Gly Gly Gly Gly Gly Gly Gly
                  95                 100                 105

 Gly Ala Pro Arg Gly Arg Tyr Gly Pro Pro Ser Arg Arg Ser Glu
                 110                 115                 120

 Asn Arg Val Val Val Ser Gly Leu Pro Pro Ser Gly Ser Trp Gln
                 125                 130                 135

 Asp Leu Lys Asp His Met Arg Glu Ala Gly Asp Val Cys Tyr Ala
                 140                 145                 150

 Asp Val Tyr Arg Asp Gly Thr Gly Val Val Glu Phe Val Arg Lys
                 155                 160                 165

 Glu Asp Met Thr Tyr Ala Val Arg Lys Leu Asp Asn Thr Lys Phe
                 170                 175                 180

 Arg Ser His Glu Gly Glu Thr Ala Tyr Ile Arg Val Lys Val Asp
                 185                 190                 195

 Gly Pro Arg Ser Pro Ser Tyr Gly Arg Ser Arg Ser Arg Ser Arg
                 200                 205                 210

 Ser Arg Ser Arg Ser Arg Ser Arg Ser Asn Ser Arg Ser Arg Ser
                 215                 220                 225

 Tyr Ser Pro Arg Arg Ser Arg Gly Ser Pro Arg Tyr Ser Pro Arg
                 230                 235                 240

 His Ser Arg Ser Arg Ser Arg Thr
                 245

<210> 441
<211> 5554
<212> DNA
<213> Homo sapien

<400> 441
 gggttaaggg cccgcgcggg ccgggggagt gcagcctcag gccgtgattg 50

 gttgcgccac ccaggccccc gcgccctgcc attggccccg cggcggcccc 100

 gcccctccgg cactcggcgc cgaagccgcg agctcgcccg ctggagctga 150

 gcgcgccgct gggccaggca gccgagccgt ccgagcagct gggctgggag 200

 cagggaaccc ggagctggga atcgggagcc gggcgcgggg agctgcgcga 250

 agccggggcg gagcacgcga gctatgatgt cgacgtacaa gcgggccacg 300

 ctggacgagg aggacctggt ggactcgctc tccgagggcg acgcataccc 350

 caacggcctg caggtgaact tccacagccc ccggagtggc cagaggtgct 400

 gggctgcacg gacccaggtg gagaagcggc tggtggtgtt ggtggtactt 450

 ctggcggcag gactggtggc ctgcttggca gcactgggca tccagtacca 500

 gacaagatcc ccctctgtgt gcctgagcga agcttgtgtc tcagtgacca 550

 gctccatctt gagctccatg gaccccacag tggacccctg ccatgacttc 600

 ttcagctacg cctgtggggg ctggatcaag gccaacccag tccctgatgg 650

 ccactcacgc tgggggacct tcagcaacct ctgggaacac aaccaagcaa 700

 tcatcaagca cctcctcgaa aactccacgg ccagcgtgag cgaggcagag 750

 agaaaggcgc aagtatacta ccgtgcgtgc atgaacgaga ccaggatcga 800

 ggagctcagg gccaaacctc taatggagtt gattgagagg ctcgggggct 850

 ggaacatcac aggtccctgg gccaaggaca acttccagga caccctgcag 900

 gtggtcaccg cccactaccg cacctcaccc ttcttctctg tctatgtcag 950

 tgccgattcc aagaactcca acagcaacgt gatccaggtg gaccagtctg 1000

 gcctgggctt gccctcgaga gactattacc tgaacaaaac tgaaaacgag 1050

 aaggtgctga ccggatatct gaactacatg gtccagctgg ggaagctgct 1100

 gggcggcggg gacgaggagg ccatccggcc ccagatgcag cagatcttgg 1150

 actttgagac ggcactggcc aacatcacca tcccacagga gaagcgccgt 1200

 gatgaggagc tcatctacca caaagtgacg gcagccgagc tgcagacctt 1250

 ggcacccgcc atcaactggt tgccttttct caacaccatc ttctaccccg 1300

 tggagatcaa tgaatccgag cctattgtgg tctatgacaa ggaatacctt 1350

 gagcagatct ccactctcat caacaccacc gacagatgcc tgctcaacaa 1400

 ctacatgatc tggaacctgg tgcggaaaac aagctccttc cttgaccagc 1450

 gctttcagga cgccgatgag aagttcatgg aagtcatgta cgggaccaag 1500

 aagacctgtc ttcctcgctg gaagttttgc gtgagtgaca cagaaaacaa 1550

 cctgggcttt gcgttgggcc ccatgtttgt caaagcaacc ttcgccgagg 1600

 acagcaagag catagccacc gagatcatcc tggagattaa gaaggcattt 1650

 gaggaaagcc tgagcaccct gaagtggatg gatgaggaaa cccgaaaatc 1700

 agccaaggaa aaggccgatg ccatctacaa catgatagga taccccaact 1750

 tcatcatgga tcccaaggag ctggacaaag tgtttaatga ctacactgca 1800

 gttccagacc tctactttga aaatgccatg cggtttttca acttctcatg 1850

 gagggtcact gccgatcagc tcaggaaagc ccccaacaga gatcagtgga 1900

 gcatgacccc gcccatggtg aacgcctact actcgcccac caagaatgag 1950

 attgtgtttc cggccgggat cctgcaggca ccattctaca cacgctcctc 2000

 acccaaggcc ttaaactttg gtggcatagg tgtcgtcgtg ggccatgagc 2050

 tgactcatgc ttttgatgat caaggacggg agtatgacaa ggacgggaac 2100

 ctccggccat ggtggaagaa ctcatccgtg gaggccttca agcgtcagac 2150

 cgagtgcatg gtagagcagt acagcaacta cagcgtgaac ggggagccgg 2200

 tgaacgggcg gcacaccctg ggggagaaca tcgccgacaa cgggggtctc 2250

 aaggcggcct atcgggctta ccagaactgg gtgaagaaga acggggctga 2300

 gcactcgctc cccaccctgg gcctcaccaa taaccagctc ttcttcctgg 2350

 gctttgcaca ggtctggtgc tccgtccgca cacctgagag ctcccacgaa 2400

 ggcctcatca ccgatcccca cagcccctct cgcttccggg tcatcggctc 2450

 cctctccaat tccaaggagt tctcagaaca cttccgctgc ccacctggct 2500

 cacccatgaa cccgcctcac aagtgcgaag tctggtaagg acgaagcgga 2550

 gagagccaag acggaggagg ggaaggggct gaggacgaga cccccatcca 2600

 gcctccaggg cattgctcag cccgcttggc cacccggggc cctgcttcct 2650

 cacactggcg ggttttcagc cggaaccgag cccatggtgt tggctctcaa 2700

 cgtgacccgc agtctgatcc cctgtgaaga gccggacatc ccaggcacac 2750

 gtgtgcgcca ccttcagcag gcattcgggt gctgggctgg tggctcatca 2800

 ggcctgggcc ccacactgac aagcgccaga tacgccacaa ataccactgt 2850

 gtcaaatgct ttcaagatat atttttgggg aaactatttt ttaaacactg 2900

 tggaatacac tggaaatctt cagggaaaaa cacatttaaa cacttttttt 2950

 tttaaggaaa gaattggtat atttattatg ttctgttttt ctaaataacc 3000

 tgtggacaag ggaagcccca ctgatttact ccctctcttc cccactccct 3050

 gtgaggctgg gctgaggcac ggatccctgg gccacagagc aagtctccaa 3100

 atcagacagc tgcctcagcc cctgggatgt gtgatttcag ctcctgtcac 3150

 ctcatgcaag ggcgtggaga ccagtagagg tgtggaggcc aggcagagag 3200

 aggagcctgc tctgcggggg gcccagctca tgggcactgc cccttcagct 3250

 agcctgcctc cgtcccctga gtccaacagt gggagcccta gctgggaagt 3300

 tctgatcccc aaagccacag caggggactg atggctatag cagaatgagg 3350

 tcgggtcagg accctcaaac accatctggg aacaccaagc accctgaatc 3400

 gagactgcag gagccctgcg gggtgagact gtgtcagaga tacactgctg 3450

 gccacaagtg tcccctctca gtcccacctt ttcgggctgt cccatgtcta 3500

 tctcaggggc ccgttacctc tctgcagcag tcccccatcc cagccacacc 3550

 agggtctgtc cggccaaccc tcttccccag ggaaaggaga aaagagaaaa 3600

 caggctgggc ccgcgtggct cactcctgta atcccagcac tttgggaggt 3650

 tgaggtgggc ggatgcacct gaggtcagga gtttgagacc agcctggcca 3700

 acgtggtgaa accccatctc tactaaaaaa aattacaaaa attagccggg 3750

 agtggtggtg ggcacctgta atcccagtta ctcgggaggc tgaggcaaga 3800

 gaatctcttg agctcaggag gcagaggttg cagtgagctg agattgcgcc 3850

 actgcactcc agcctgggtg acagagggag actccgtccc aaaaaaaaag 3900

 aaaagagaaa cagctgtcac ctcccgcagg acccaaatcc tctctctgag 3950

 caccgtcatc caccacatgg ctgggcctgg ctcccaggac cagtccagtc 4000

 ctctagtgcc ttatctgagg ctgcagccgc cagtctccac cccaaggaga 4050

 cagcccctgc tcctagatgc ccttggcctc cgcagtgcag cccccaggtg 4100

 tcctgactga agcacaggcc atagccccat ttccccggtg cctgcagggc 4150

 taacctccac gggagcccag gagctctggc cggcaggtcc atggcacagg 4200

 gcatcggaag actgcaaaac tgctggactt accctgggct gcagtccatt 4250

 gtcggcccct gggttgaatc aagatagtac ttgcagctag atggatgctt 4300

 ttagccaggg gacattgtga ggggaagatt cctccaccca gtctggcctg 4350

 tggtgtctgt ctcctccctg agaccacagc ttctccagta gcagactcat 4400

 gggcgccacc aagtggaagc acctggagcg gcctctgcca tccagtgggg 4450

 aagccaggcc ccgagacgga ggtgggggca gcacgtgccc tccacagcca 4500

 ccgctttccc gcctcagcag cccaggcctc ctggcccagc cctgcctgga 4550

 cagtgctctc ccctcacccg ggaagctgga atcctcctgc ccgagaggaa 4600

 gcagacggca cagggacacc cctgccacct tgggatctgc ctccaagctg 4650

 gtgcagggta tcgagagtgg attccagatg gaggtcctgg tcccagcacg 4700

 cagcagtcct ggtagctctg cagaggagac aggaacccga gaagtagctg 4750

 aagcagaagc cagccgcagt ccccttgcca catagaggcg ggcttctccc 4800

 agccatggtg tcccctctgc ctcccctccc ccgaccctcc tgccttccgc 4850

 gtggagggtg gtggtcctgt agtgtcagca ccagcaccat gggcttggac 4900

 cccctccctg gacacaggca ggtgtcctag ggctgggggt gcagcccgag 4950

 ggaatggaga ccacactcat ggctcaggtc tgccggggcc ggcagggggt 5000

 tggggaagaa gagggctcag gcccagcagg ggtggaagcc cctgccactg 5050

 ccactacccg ctccagagct ttaaggaaaa tgaagtgaga cccctcccct 5100

 taggcctggg gagccatagg gctggcttct ctgtgggtgc gtggacgtgg 5150

 ggttgggagc tgggaatcta ttttttgtat tatgttttga gctactgtag 5200

 ttttggcgtg gcactattgt aatggaaata aaatacttgt acggagggcc 5250

 atgtgtctgg gtgtctgtcc tcccaaggtg ctgtgtgtcc tttgaggccg 5300

 gcacagggct gtccacccta gcttctccag ggctgggcgc atctgtccct 5350

 gagagcaggg gtcttggacc ctgacaaatg ccagaaggtt gctcagtacc 5400

 tgtgccccca gccacccttc cttcacctac aagtgtgtga gcaccccctg 5450

 ctggtgagaa tgatgcacat caccacctgg gtccaagagg cctcctggta 5500

 aaaataattt ttctgttatc ttcgagcaag ggagtttcca ggtctcagat 5550

 gttt 5554

<210> 442
<211> 845
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 50
<223> unknown amino acid

<400> 442
 Gly Leu Arg Ala Arg Ala Gly Arg Gly Ser Ala Ala Ser Gly Arg
   1               5                  10                  15

 Asp Trp Leu Arg His Pro Gly Pro Arg Ala Leu Pro Leu Ala Pro
                  20                  25                  30

 Arg Arg Pro Arg Pro Ser Gly Thr Arg Arg Arg Ser Arg Glu Leu
                  35                  40                  45

 Ala Arg Trp Ser Xaa Ala Arg Arg Trp Ala Arg Gln Pro Ser Arg
                  50                  55                  60

 Pro Ser Ser Trp Ala Gly Ser Arg Glu Pro Gly Ala Gly Asn Arg
                  65                  70                  75

 Glu Pro Gly Ala Gly Ser Cys Ala Lys Pro Gly Arg Ser Thr Arg
                  80                  85                  90

 Ala Met Met Ser Thr Tyr Lys Arg Ala Thr Leu Asp Glu Glu Asp
                  95                 100                 105

 Leu Val Asp Ser Leu Ser Glu Gly Asp Ala Tyr Pro Asn Gly Leu
                 110                 115                 120

 Gln Val Asn Phe His Ser Pro Arg Ser Gly Gln Arg Cys Trp Ala
                 125                 130                 135

 Ala Arg Thr Gln Val Glu Lys Arg Leu Val Val Leu Val Val Leu
                 140                 145                 150

 Leu Ala Ala Gly Leu Val Ala Cys Leu Ala Ala Leu Gly Ile Gln
                 155                 160                 165

 Tyr Gln Thr Arg Ser Pro Ser Val Cys Leu Ser Glu Ala Cys Val
                 170                 175                 180

 Ser Val Thr Ser Ser Ile Leu Ser Ser Met Asp Pro Thr Val Asp
                 185                 190                 195

 Pro Cys His Asp Phe Phe Ser Tyr Ala Cys Gly Gly Trp Ile Lys
                 200                 205                 210

 Ala Asn Pro Val Pro Asp Gly His Ser Arg Trp Gly Thr Phe Ser
                 215                 220                 225

 Asn Leu Trp Glu His Asn Gln Ala Ile Ile Lys His Leu Leu Glu
                 230                 235                 240

 Asn Ser Thr Ala Ser Val Ser Glu Ala Glu Arg Lys Ala Gln Val
                 245                 250                 255

 Tyr Tyr Arg Ala Cys Met Asn Glu Thr Arg Ile Glu Glu Leu Arg
                 260                 265                 270

 Ala Lys Pro Leu Met Glu Leu Ile Glu Arg Leu Gly Gly Trp Asn
                 275                 280                 285

 Ile Thr Gly Pro Trp Ala Lys Asp Asn Phe Gln Asp Thr Leu Gln
                 290                 295                 300

 Val Val Thr Ala His Tyr Arg Thr Ser Pro Phe Phe Ser Val Tyr
                 305                 310                 315

 Val Ser Ala Asp Ser Lys Asn Ser Asn Ser Asn Val Ile Gln Val
                 320                 325                 330

 Asp Gln Ser Gly Leu Gly Leu Pro Ser Arg Asp Tyr Tyr Leu Asn
                 335                 340                 345

 Lys Thr Glu Asn Glu Lys Val Leu Thr Gly Tyr Leu Asn Tyr Met
                 350                 355                 360

 Val Gln Leu Gly Lys Leu Leu Gly Gly Gly Asp Glu Glu Ala Ile
                 365                 370                 375

 Arg Pro Gln Met Gln Gln Ile Leu Asp Phe Glu Thr Ala Leu Ala
                 380                 385                 390

 Asn Ile Thr Ile Pro Gln Glu Lys Arg Arg Asp Glu Glu Leu Ile
                 395                 400                 405

 Tyr His Lys Val Thr Ala Ala Glu Leu Gln Thr Leu Ala Pro Ala
                 410                 415                 420

 Ile Asn Trp Leu Pro Phe Leu Asn Thr Ile Phe Tyr Pro Val Glu
                 425                 430                 435

 Ile Asn Glu Ser Glu Pro Ile Val Val Tyr Asp Lys Glu Tyr Leu
                 440                 445                 450

 Glu Gln Ile Ser Thr Leu Ile Asn Thr Thr Asp Arg Cys Leu Leu
                 455                 460                 465

 Asn Asn Tyr Met Ile Trp Asn Leu Val Arg Lys Thr Ser Ser Phe
                 470                 475                 480

 Leu Asp Gln Arg Phe Gln Asp Ala Asp Glu Lys Phe Met Glu Val
                 485                 490                 495

 Met Tyr Gly Thr Lys Lys Thr Cys Leu Pro Arg Trp Lys Phe Cys
                 500                 505                 510

 Val Ser Asp Thr Glu Asn Asn Leu Gly Phe Ala Leu Gly Pro Met
                 515                 520                 525

 Phe Val Lys Ala Thr Phe Ala Glu Asp Ser Lys Ser Ile Ala Thr
                 530                 535                 540

 Glu Ile Ile Leu Glu Ile Lys Lys Ala Phe Glu Glu Ser Leu Ser
                 545                 550                 555

 Thr Leu Lys Trp Met Asp Glu Glu Thr Arg Lys Ser Ala Lys Glu
                 560                 565                 570

 Lys Ala Asp Ala Ile Tyr Asn Met Ile Gly Tyr Pro Asn Phe Ile
                 575                 580                 585

 Met Asp Pro Lys Glu Leu Asp Lys Val Phe Asn Asp Tyr Thr Ala
                 590                 595                 600

 Val Pro Asp Leu Tyr Phe Glu Asn Ala Met Arg Phe Phe Asn Phe
                 605                 610                 615

 Ser Trp Arg Val Thr Ala Asp Gln Leu Arg Lys Ala Pro Asn Arg
                 620                 625                 630

 Asp Gln Trp Ser Met Thr Pro Pro Met Val Asn Ala Tyr Tyr Ser
                 635                 640                 645

 Pro Thr Lys Asn Glu Ile Val Phe Pro Ala Gly Ile Leu Gln Ala
                 650                 655                 660

 Pro Phe Tyr Thr Arg Ser Ser Pro Lys Ala Leu Asn Phe Gly Gly
                 665                 670                 675

 Ile Gly Val Val Val Gly His Glu Leu Thr His Ala Phe Asp Asp
                 680                 685                 690

 Gln Gly Arg Glu Tyr Asp Lys Asp Gly Asn Leu Arg Pro Trp Trp
                 695                 700                 705

 Lys Asn Ser Ser Val Glu Ala Phe Lys Arg Gln Thr Glu Cys Met
                 710                 715                 720

 Val Glu Gln Tyr Ser Asn Tyr Ser Val Asn Gly Glu Pro Val Asn
                 725                 730                 735

 Gly Arg His Thr Leu Gly Glu Asn Ile Ala Asp Asn Gly Gly Leu
                 740                 745                 750

 Lys Ala Ala Tyr Arg Ala Tyr Gln Asn Trp Val Lys Lys Asn Gly
                 755                 760                 765

 Ala Glu His Ser Leu Pro Thr Leu Gly Leu Thr Asn Asn Gln Leu
                 770                 775                 780

 Phe Phe Leu Gly Phe Ala Gln Val Trp Cys Ser Val Arg Thr Pro
                 785                 790                 795

 Glu Ser Ser His Glu Gly Leu Ile Thr Asp Pro His Ser Pro Ser
                 800                 805                 810

 Arg Phe Arg Val Ile Gly Ser Leu Ser Asn Ser Lys Glu Phe Ser
                 815                 820                 825

 Glu His Phe Arg Cys Pro Pro Gly Ser Pro Met Asn Pro Pro His
                 830                 835                 840

 Lys Cys Glu Val Trp
                 845

<210> 443
<211> 2154
<212> DNA
<213> Homo sapien

<400> 443
 atataaccgc gtggcccgcg cgcgcgcttc cctcccggcg cagtcaccgg 50

 cgcggtctat ggctgcgact tctctaatgt ctgctttggc tgcccggctg 100

 ctgcagcccg cgcacagctg ctcccttcgc cttcgccctt tccacctcgc 150

 ggcagttcga aatgaagctg ttgtcatttc tggaaggaaa ctggcccagc 200

 agatcaagca ggaagtgcgg caggaggtag aagagtgggt ggcctcaggc 250

 aacaaacggc cacacctgag tgtgatcctg gttggcgaga atcctgcaag 300

 tcactcctat gtcctcaaca aaaccagggc agctgcagtt gtgggaatca 350

 acagtgagac aattatgaaa ccagcttcaa tttcagagga agaattgttg 400

 aatttaatca ataaactgaa taatgatgat aatgtagatg gcctccttgt 450

 tcagttgcct cttccagagc atattgatga gagaaggatc tgcaatgctg 500

 tttctccaga caaggatgtt gatggctttc atgtaattaa tgtaggacga 550

 atgtgtttgg atcagtattc catgttaccg gctactccat ggggtgtgtg 600

 ggaaataatc aagcgaactg gcattccaac cctagggaag aatgtggttg 650

 tggctggaag gtcaaaaaac gttggaatgc ccattgcaat gttactgcac 700

 acagatgggg cgcatgaacg tcccggaggt gatgccactg ttacaatatc 750

 tcatcgatat actcccaaag agcagttgaa gaaacataca attcttgcag 800

 atattgtaat atctgctgca ggtattccaa atctgatcac agcagatatg 850

 atcaaggaag gagcagcagt cattgatgtg ggaataaata gagttcacga 900

 tcctgtaact gccaaaccca agttggttgg agatgtggat tttgaaggag 950

 tcagacaaaa agctgggtat atcactccag ttcctggagg tgttggcccc 1000

 atgacagtgg caatgctaat gaagaatacc attattgctg caaaaaaggt 1050

 gctgaggctt gaagagcgag aagtgctgaa gtctaaagag cttggggtag 1100

 ccactaatta actactgtgt cttctgtgtc acaaacagca ctccaggcca 1150

 gctcaagaag caaagcaggc caatagaaat gcaatatttt taatttattc 1200

 tactgaaatg gtttaaaatg atgccttgta tttattgaaa gcttaaatgg 1250

 gtgggtgttt ctgcacatac ctctgcagta cctcaccagg gagcattcca 1300

 gtatcatgca gggtcctgtg atctagccag gagcagccat taacctagtg 1350

 attaatatgg gagacattac catatggagg atggatgctt cactttgtca 1400

 agcacctcag ttacacattc gccttttcta ggattgcatt tcccaagtgc 1450

 tattgcaata acagttgata ctcattttag gtaccagacc ttttgagttc 1500

 aactgatcaa accaaaggaa aagtgttgct agagaaaatt ggggaaaagg 1550

 tgaaaaagaa aaaatggtag taattgagca gaaaaaaatt aatttatata 1600

 tgtattgatt ggcaaccaga tttatctaag tagaactgaa ttggctagga 1650

 aaaaagaaaa actgcatgtt aatcattttc ctaagctgtc cttttgaggc 1700

 ttagtcagtt tattgggaaa atgtttagga ttattccttg ctattagtac 1750

 tcattttatg tatgttaccc ttcagtaagt tctccccatt ttagttttct 1800

 aggactgaaa ggattctttt ctacattata catgtgtgtt gtcatatttg 1850

 gcttttgcta tatactttaa cttcattgtt aaatttttgt attgtatagt 1900

 ttctttggtg tatcttaaaa cctatttttg aaaaacaaac ttggcttgat 1950

 aatcatttgg gcagcttggg taagtacgca acttactttt ccaccaaaga 2000

 actgtcagca gctgcctgct tttctgtgat gtatgtatcc tgttgacttt 2050

 tccagaaatt ttttaagagt ttgagttact attgaattta atcagacttt 2100

 ctgattaaag ggttttcttt cttttttaat aaaacacatc tgtctggtat 2150

 ggta 2154

<210> 444
<211> 344
<212> PRT
<213> Homo sapien

<400> 444
 Met Ser Ala Leu Ala Ala Arg Leu Leu Gln Pro Ala His Ser Cys
   1               5                  10                  15

 Ser Leu Arg Leu Arg Pro Phe His Leu Ala Ala Val Arg Asn Glu
                  20                  25                  30

 Ala Val Val Ile Ser Gly Arg Lys Leu Ala Gln Gln Ile Lys Gln
                  35                  40                  45

 Glu Val Arg Gln Glu Val Glu Glu Trp Val Ala Ser Gly Asn Lys
                  50                  55                  60

 Arg Pro His Leu Ser Val Ile Leu Val Gly Glu Asn Pro Ala Ser
                  65                  70                  75

 His Ser Tyr Val Leu Asn Lys Thr Arg Ala Ala Ala Val Val Gly
                  80                  85                  90

 Ile Asn Ser Glu Thr Ile Met Lys Pro Ala Ser Ile Ser Glu Glu
                  95                 100                 105

 Glu Leu Leu Asn Leu Ile Asn Lys Leu Asn Asn Asp Asp Asn Val
                 110                 115                 120

 Asp Gly Leu Leu Val Gln Leu Pro Leu Pro Glu His Ile Asp Glu
                 125                 130                 135

 Arg Arg Ile Cys Asn Ala Val Ser Pro Asp Lys Asp Val Asp Gly
                 140                 145                 150

 Phe His Val Ile Asn Val Gly Arg Met Cys Leu Asp Gln Tyr Ser
                 155                 160                 165

 Met Leu Pro Ala Thr Pro Trp Gly Val Trp Glu Ile Ile Lys Arg
                 170                 175                 180

 Thr Gly Ile Pro Thr Leu Gly Lys Asn Val Val Val Ala Gly Arg
                 185                 190                 195

 Ser Lys Asn Val Gly Met Pro Ile Ala Met Leu Leu His Thr Asp
                 200                 205                 210

 Gly Ala His Glu Arg Pro Gly Gly Asp Ala Thr Val Thr Ile Ser
                 215                 220                 225

 His Arg Tyr Thr Pro Lys Glu Gln Leu Lys Lys His Thr Ile Leu
                 230                 235                 240

 Ala Asp Ile Val Ile Ser Ala Ala Gly Ile Pro Asn Leu Ile Thr
                 245                 250                 255

 Ala Asp Met Ile Lys Glu Gly Ala Ala Val Ile Asp Val Gly Ile
                 260                 265                 270

 Asn Arg Val His Asp Pro Val Thr Ala Lys Pro Lys Leu Val Gly
                 275                 280                 285

 Asp Val Asp Phe Glu Gly Val Arg Gln Lys Ala Gly Tyr Ile Thr
                 290                 295                 300

 Pro Val Pro Gly Gly Val Gly Pro Met Thr Val Ala Met Leu Met
                 305                 310                 315

 Lys Asn Thr Ile Ile Ala Ala Lys Lys Val Leu Arg Leu Glu Glu
                 320                 325                 330

 Arg Glu Val Leu Lys Ser Lys Glu Leu Gly Val Ala Thr Asn
                 335                 340

<210> 445
<211> 5766
<212> DNA
<213> Homo sapien

<400> 445
 cgccgccgca gccgccgcca ccaacgccaa caacaacgtg tcgggagcag 50

 ccgcggccga agccggagca ggggccggag tcgcggctgg agtggggcct 100

 gcgcgtgtga gtggccgaga gttgcccgtg ccggagacct caaactccgg 150

 gcgggagcgc tttcggtggg ccgagccgcc gtcgcccgcg gcaccgtgtc 200

 cccaaggccc agacagcggg gcgggggtct atcaggcgcg ggactggctt 250

 ctctcaggcc gacccttcta gccgggctcc ggatcttcct cggcctcggg 300

 cccccttcac gttcaggacg gaggccggag aacggtgatc atcacacacc 350

 ccagccggct tcctggccag ggcattttct ctgcggccaa gcagtgttgg 400

 gattgtagct gctgggagcc ccctcctgcc gccacctctc ctgcaaggaa 450

 gggactgacg cgttcccact ttcttactct gcacctcccc actctcttcc 500

 cattcaagaa cgagtttctc ttccctctcc attggaaatc ctgctccgga 550

 ggtccaaaac acgtatttta agcgtgccct tcctcacctc ctggagcacc 600

 cttagaagta ttgcctactt atccgggctg agaatccttc atttttgacc 650

 tggctttttt ttcgcccttt gggagataaa ggtccctctc caccctctac 700

 taacactctg cacccaaggc cttatccttt ggggtcacca gctccttggc 750

 catttctatg tgatttcccc cacccatctg agttccagtt tcctctgggc 800

 tccaatctcc agtccctggc ggatctggtc agtcccaccc ctaggtggga 850

 gtgaccaggg ggctctggcc caggattccc aaccctggaa ggcagctcca 900

 aggcaggaag agaattgggc atcgggtacg aacctggcag ctcaggagtc 950

 ggggctccac tcaccccaca caaaaagatg aaaaagcgca aagagctcaa 1000

 tgcattgatt ggtttggctg gggacagccg gagaaagaag cccaagaaag 1050

 gcccaagcag tcaccgcctg cttcgcactg agcctcccga ctcagactct 1100

 gagtccagct ccgaagagga agaggaattc ggtgtggttg gaaatcgctc 1150

 tcgctttgcc aagggagact atttacgatg ctgcaagatc tgttatccgc 1200

 tctgtggttt tgtcatcctt gctgcctgtg ttgtggcctg tgttggcttg 1250

 gtgtggatgc aggttgctct caaggaggat ctggatgccc tcaaggaaaa 1300

 atttcgaaca atggaatcta atcagaaaag ctcattccaa gaaatcccca 1350

 aacttaatga agaactactc agcaagcaaa aacaacttga gaagattgaa 1400

 tctggagaga tgggtttgaa caaagtctgg ataaacatca cagaaatgaa 1450

 taagcagatt tctctgttga cttctgcagt gaaccacctc aaagccaatg 1500

 ttaagtcagc tgcagacttg attagcctgc ctaccactgt agagggactt 1550

 cagaagagtg tagcttccat tggcaatact ttaaacagcg tccatcttgc 1600

 tgtggaagca ctacagaaaa ctgtggatga acacaagaaa acgatggaat 1650

 tactgcagag tgatatgaat cagcacttct tgaaggagac tcctggaagc 1700

 aaccagatca ttccgtcacc ttcagccaca tcagaacttg acaataaaac 1750

 ccacagtgag aatttgaaac aggatatcct gtaccttcac aactctttag 1800

 aggaggtaaa cagtgcccta gtggggtacc agagacagaa tgatcttaaa 1850

 ctcgagggaa tgaacgagac agtcagtaat cttacccaga gagtcaacct 1900

 gatagaaagc gatgtggttg ctatgagcaa ggtagaaaag aaagcaaacc 1950

 tgtccttcag catgatgggt gatagatctg ccactctgaa aagacagtct 2000

 ttggatcaag tcaccaacag aacagataca gtaaaaatcc aaagcataaa 2050

 gaaagaagat agttcaaatt ctcaggtatc caagctaaga gagaaactcc 2100

 agctgatcag tgctcttaca aacaaacctg agagcaacag gcctccagag 2150

 accgccgatg aagagcaagt agagagtttc acatcaaagc catcagcatt 2200

 gccaaaattt tcacagtttc ttggagaccc agttgagaaa gctgcccaac 2250

 taagacctat ctccctacca ggagtttcta gcactgaaga tcttcaggat 2300

 ttattccgca agactggcca ggacgtggat gggaagctga cctaccagga 2350

 aatctggacc tccctaggtt ctgctatgcc agaaccagag agcttgagag 2400

 catttgattc cgatggagat ggaagatact cattcctgga gctaagggta 2450

 gctttaggta tctagcttca tcaggcatat tttagaaatg gactgcctaa 2500

 tatctattta cctaacaaca aaacaaccct tacttaccca tcagtcctct 2550

 agtcctccaa actactgtag cagatacttt gccacctttt aacttgtttg 2600

 aagaagctat ataaaagtta tttttttaaa gaagaagacc attttactta 2650

 tgatgttcag aaatctatga tttcctacaa ccagtaagat cttacatttt 2700

 aaaattgcca gaaaaaaaat taaagccctc tttttttctc tttccttttt 2750

 ttgaggggag gagaccttat cttttaaagc tgggaaatgt atatagagag 2800

 agaataagcc acttttatat ttcacttaaa tttgccttaa attagctgca 2850

 ctttatagag actcagaaaa tgtcttttct ttaaaagata ggccttttct 2900

 gtttgtaaat atttaaatga aagaaagcat tgtgcatatt gtgtggaaag 2950

 taggaagaat ggttttgaac aggatatgaa caaatgactt attaaaaatt 3000

 gctgatctgg tgtaggtggc agctgaaact acatccatgt ctccataagg 3050

 catccctcaa aggcccaggc gctgccaggg ggtttgtcct ggtagctgga 3100

 ggaaccgatt tcagggaata gacactggag acaatactga ctccaggcat 3150

 ggctcatgga agtaggattc tggttctttg ttcctattcc ctcagctaat 3200

 cccaacctgg gaatcagaga agtcttgggg atttttctca tttttagtac 3250

 tatttcaggg tttatgagca taaaaagtta tccattgggg agctccattt 3300

 tccctgctga gtgagctaga ttgccttccc cacccaccca cttaagtctg 3350

 tcttaaagcc gtagctggct cccaccacca gtaccatctc catttgaatg 3400

 gcagggctaa attcccccag ccattatctc acactgacca cccagagctt 3450

 tagaagagag ctgtgcttct aattttgacc cagaaaacca taccccttga 3500

 gattttacct agaggctaac caagagccta atatgtttct ctgggggatg 3550

 actaaagcca aaaaggctgt gagatgaaac atgtgaaata atattcagtt 3600

 tccttaccat taccagctca gaagtagcta gaggctttct acccaaagga 3650

 tgccaaagta tagcagggca ggcctggagc tagggccttc acatggtggt 3700

 agcaagtttt tcaaatctaa tacaatcaag tacaatactt cctttaaatg 3750

 cttctgtgga cctggcatga aagatcccta gattgaaagg aataatacct 3800

 ccatgtctcc tgtatgttga gtctagaatt gctgtgttgt tcttagaagc 3850

 agtctttggg caacaacttg aaaggggaaa aaaaaactac aaaaacttaa 3900

 ctttggtata ggccaagtca gggagaaagt agagaaagct gtcatgccac 3950

 agacttcttt agtggagatc atttcctttt taactttgtt caggttgccc 4000

 ttcaccatgg atacagtccg gtacccttaa acatttaagg gctgtttttt 4050

 tttttcttta tatgatgttc agcttggtat taaccaaact taaatttttt 4100

 ttccagaagt attaaaattt agttaaagca agatgaagtc ttttcccatg 4150

 aatgtgtccc cttatctcat tatagcttat gctcagtttc actttcttgg 4200

 aaaggttaaa acaaattagc ctggcacttt aggtaacttg aaaataactc 4250

 tcacccttct gactgccttc catccactct caccccacac ctttttttaa 4300

 tatatataca cccttacaga ttttctaaca accaaataaa attctagcaa 4350

 taaattgaat tatactgcta tatttgtata tactgtacca taaatagtat 4400

 gtctgtacct ggaaggtatt tttttgagaa ctgatttata tgaaatatac 4450

 ttgagggtaa tgtagcttgt cctttttagt ttcaaattct tattcatagg 4500

 cagatacttt gaagacacct taactctttg ttgtgtgtat tttcccttgc 4550

 atcagataac tatacatgga gaaatccatt ttgttttttg gtttatcttc 4600

 tgttcttcct accttgtgct tgtctgacta gtatcacccc tgagccagta 4650

 tacagtacca tcctctcccc ctaccaagtt tggcagaggt gtttatactg 4700

 cattctcaga tctatgaata tttttgtcat cctgcctgag aaagtacatc 4750

 ttccaggcaa aagtagggta tcttgaactc ctttcttctg agttgagcag 4800

 actcactggc ttaagcatcc cataagccta ttatttagtg tgaatttggg 4850

 acttttattt gtatgttgtc ttaacttact gagcctgtga cttgtattta 4900

 gctgtagtca agcctcacca gccatatctc atctctgaga ggaagactgg 4950

 atagtgagtt tggttttggt tttggtttta aaccctttta ccttttcagt 5000

 ctggcagctc ctactgctgc tttcctaagt tactcaaagc actgcttctt 5050

 ggtccttgtt ttcttttgcc ttgtactatc ttgtataatg tttactaaaa 5100

 gagcctcccc ataaatcaga gaggcaaaaa ggtagcatat aaaaagaaga 5150

 accaaaagaa gagaaaacct gacttctaga tgactgtggt gtcatctaaa 5200

 aggcagaggt gcctgaccct caggaatgtg tatgatgcaa cagagctgaa 5250

 gaatgggttc ccttcaccta ctgctggcca ttgtcccttc tgttggagat 5300

 tcctttcttt atggttgctg ttcataaccc cttcaacacc cccccttgct 5350

 ggtcctgccg gtcacagttg aggattttgg ctgtgatggg ctcatactca 5400

 taatggcctg ttgagttgtt tttagtgaca ggttttgttt gctgcacacc 5450

 tcattggctt gcttaccaac accagctaga agtggtccct ctttcatatc 5500

 caaaccagaa cacatttggg tattcctgag actttataga gcgtgtattg 5550

 tttgttatac gaacctaacc taccttgttg ttttctcata ttaagaaatt 5600

 taaatctact ttgttttagt gaagctattt tggtaatgta taagcaattt 5650

 tggttctgtt tagggagaat tcagggtttc catgacttga tttgagcttt 5700

 gcatatttca aataagtaac acagccattt taatttagct aaataaaaaa 5750

 atttcttttt tctctc 5766

<210> 446
<211> 495
<212> PRT
<213> Homo sapien

<400> 446
 Met Lys Lys Arg Lys Glu Leu Asn Ala Leu Ile Gly Leu Ala Gly
   1               5                  10                  15

 Asp Ser Arg Arg Lys Lys Pro Lys Lys Gly Pro Ser Ser His Arg
                  20                  25                  30

 Leu Leu Arg Thr Glu Pro Pro Asp Ser Asp Ser Glu Ser Ser Ser
                  35                  40                  45

 Glu Glu Glu Glu Glu Phe Gly Val Val Gly Asn Arg Ser Arg Phe
                  50                  55                  60

 Ala Lys Gly Asp Tyr Leu Arg Cys Cys Lys Ile Cys Tyr Pro Leu
                  65                  70                  75

 Cys Gly Phe Val Ile Leu Ala Ala Cys Val Val Ala Cys Val Gly
                  80                  85                  90

 Leu Val Trp Met Gln Val Ala Leu Lys Glu Asp Leu Asp Ala Leu
                  95                 100                 105

 Lys Glu Lys Phe Arg Thr Met Glu Ser Asn Gln Lys Ser Ser Phe
                 110                 115                 120

 Gln Glu Ile Pro Lys Leu Asn Glu Glu Leu Leu Ser Lys Gln Lys
                 125                 130                 135

 Gln Leu Glu Lys Ile Glu Ser Gly Glu Met Gly Leu Asn Lys Val
                 140                 145                 150

 Trp Ile Asn Ile Thr Glu Met Asn Lys Gln Ile Ser Leu Leu Thr
                 155                 160                 165

 Ser Ala Val Asn His Leu Lys Ala Asn Val Lys Ser Ala Ala Asp
                 170                 175                 180

 Leu Ile Ser Leu Pro Thr Thr Val Glu Gly Leu Gln Lys Ser Val
                 185                 190                 195

 Ala Ser Ile Gly Asn Thr Leu Asn Ser Val His Leu Ala Val Glu
                 200                 205                 210

 Ala Leu Gln Lys Thr Val Asp Glu His Lys Lys Thr Met Glu Leu
                 215                 220                 225

 Leu Gln Ser Asp Met Asn Gln His Phe Leu Lys Glu Thr Pro Gly
                 230                 235                 240

 Ser Asn Gln Ile Ile Pro Ser Pro Ser Ala Thr Ser Glu Leu Asp
                 245                 250                 255

 Asn Lys Thr His Ser Glu Asn Leu Lys Gln Asp Ile Leu Tyr Leu
                 260                 265                 270

 His Asn Ser Leu Glu Glu Val Asn Ser Ala Leu Val Gly Tyr Gln
                 275                 280                 285

 Arg Gln Asn Asp Leu Lys Leu Glu Gly Met Asn Glu Thr Val Ser
                 290                 295                 300

 Asn Leu Thr Gln Arg Val Asn Leu Ile Glu Ser Asp Val Val Ala
                 305                 310                 315

 Met Ser Lys Val Glu Lys Lys Ala Asn Leu Ser Phe Ser Met Met
                 320                 325                 330

 Gly Asp Arg Ser Ala Thr Leu Lys Arg Gln Ser Leu Asp Gln Val
                 335                 340                 345

 Thr Asn Arg Thr Asp Thr Val Lys Ile Gln Ser Ile Lys Lys Glu
                 350                 355                 360

 Asp Ser Ser Asn Ser Gln Val Ser Lys Leu Arg Glu Lys Leu Gln
                 365                 370                 375

 Leu Ile Ser Ala Leu Thr Asn Lys Pro Glu Ser Asn Arg Pro Pro
                 380                 385                 390

 Glu Thr Ala Asp Glu Glu Gln Val Glu Ser Phe Thr Ser Lys Pro
                 395                 400                 405

 Ser Ala Leu Pro Lys Phe Ser Gln Phe Leu Gly Asp Pro Val Glu
                 410                 415                 420

 Lys Ala Ala Gln Leu Arg Pro Ile Ser Leu Pro Gly Val Ser Ser
                 425                 430                 435

 Thr Glu Asp Leu Gln Asp Leu Phe Arg Lys Thr Gly Gln Asp Val
                 440                 445                 450

 Asp Gly Lys Leu Thr Tyr Gln Glu Ile Trp Thr Ser Leu Gly Ser
                 455                 460                 465

 Ala Met Pro Glu Pro Glu Ser Leu Arg Ala Phe Asp Ser Asp Gly
                 470                 475                 480

 Asp Gly Arg Tyr Ser Phe Leu Glu Leu Arg Val Ala Leu Gly Ile
                 485                 490                 495

<210> 447
<211> 3714
<212> DNA
<213> Homo sapien

<400> 447
 ccgggttgct gtgcgactat tctccgggag ccgttcgtgt caccgccgga 50

 acctggcgca ggttaattat agaaaatgcc aagtaggaaa tttgccgatg 100

 gtgaagtggt aagaggtcga tggcctggga gttcacttta ttatgaagta 150

 gaaattctga gccacgacag cacctcccag ctttacactg tgaagtataa 200

 agatggaaca gagcttgaat tgaaagagaa tgatattaag cctttaactt 250

 cctttaggca aaggaaaggt ggctcaactt ccagttcccc ttccagacgc 300

 cgagggagtc gatcaaggtc acgctcccga tcccctggtc gaccacctaa 350

 aagtgcccgc cgatctgctt ctgcttccca ccaggccgac attaaggaag 400

 caaggaggga agtggaagtt aaattgactc cgctgattct gaagccattt 450

 ggaaatagca tcagcagata taatggggag cctgagcata ttgagagaaa 500

 tgacgcacct cataaaaata cacaggaaaa attcagtttg tcacaagaaa 550

 gcagttacat agcaacacag tatagccttc gtccaagaag agaagaagtc 600

 aaattaaaag aaatagattc taaggaagaa aaatacgttg caaaagaact 650

 ggcagtgaga acctttgaag tgacccccat ccgggcaaag gacttggagt 700

 ttggaggagt acctggtgtg tttctcatca tgtttggcct gcctgtgttc 750

 ctcttcctgt tgctgttgat gtgtaaacag aaagatccca gtcttctgaa 800

 tttccctcct cctttgccag ctttgtatga gttatgggaa accagagtat 850

 ttggggtcta cctcctgtgg tttttgattc aagtcctgtt ctacctactg 900

 ccaattggaa aggttgtaga aggaacgcct cttattgatg gaagaagact 950

 caagtataga ttaaatggat tctatccttt tatcctgaca tctgcagtca 1000

 tcggaacatc tctcttccag ggcgtagagt ttcattacgt gtacagtcat 1050

 tttcttcagt ttgcacttgc ggccactgtt ttttgtgtgg tcttgagtgt 1100

 gtatctctac atgcgctctt tgaaagcgcc ccggaatgac ctgtcgcctg 1150

 ccagctctgg aaatgctgtc tatgatttct tcattggccg tgaattaaac 1200

 cctcgaattg gtacttttga tctcaaatac ttttgtgaat tgcgccccgg 1250

 attgattgga tgggtggtta ttaacttggt gatgcttttg gctgaaatga 1300

 aaatacagga ccgcgctgtt ccatccttgg ccatgatttt agttaatagt 1350

 ttccagcttc tctatgtggt ggatgctctc tggaatgagg aagcgttgtt 1400

 gacgaccatg gacatcatcc acgatggatt tggattcatg ctggcttttg 1450

 gagacttggt gtgggttccc tttatttaca gcttccaagc cttttattta 1500

 gtcagtcatc caaatgaagt gtcttggcca atggcttctc taattattgt 1550

 tctgaaactt tgtggttatg taatcttccg aggtgcaaat tctcagaaaa 1600

 atgcattccg gaaaaatccc agtgatccaa agcttgcaca tttaaaaacc 1650

 attcatactt caagtggaaa aaatcttcta gtttctggat ggtggggctt 1700

 tgttcgccac cccaattact tgggtgatct catcatggcc ttggcgtggt 1750

 ccctcccatg tggttttaac cacattctgc cttatttcta cataatttat 1800

 ttcaccatgt tgcttgtcca ccgagaagct cgtgacgagt accactgtaa 1850

 gaagaaatac ggcgtggctt gggaaaagta ctgtcagcgt gtgccctacc 1900

 gtatatttcc atacatctac taatgctctt ctggcttttc tacaaaatac 1950

 tcctgcaatt ccagctgcca tttgcaaaaa caggaaaaaa atccgaaact 2000

 ttcttttgtt gcactgacag ggtctgtact tttttttttc tttttgagtc 2050

 aggactatgg agccgagtag ttgatctttt aatatagccg tgtttacttg 2100

 tattaactta cagttaacat aggaaaaata caagtaagga tgtgagaatt 2150

 tgcattttaa tgggaaattt tcaaccctta atctgaaaac agaagacagt 2200

 cttaatataa atgtactgtg aagaatgcta ttgatgttta tggtttctga 2250

 ttacttttca aattttgatg tttttttgcc agttggcttt tcttaaatga 2300

 aaacactgtt ccatttaaag tacatttatg ttttattcag taagagaata 2350

 gaattttcat ttgtttttct ttaaatcctt tactaattat ataatttgaa 2400

 agcaaaaaga agggcctata ttaaatgctg aaagtgaaaa gtgatgacat 2450

 tattagcaga cactgcttaa aggagaccat ttgtagcagt tggcttaacc 2500

 tcaacttcta aaactacatt gaaaatgtaa atacatagct tagttttttg 2550

 taatatatgg tgacttcaga tttttttgta cagtattttg aatgtgagat 2600

 gattgtcagg actaactgtc tttttaacaa aacattttca gtattttaaa 2650

 taaaattttg taaagtaatg tgaattaaaa attttggaac aattagaatt 2700

 cattcactat tgtatagaag atgctgttaa aacataggaa gggtattttt 2750

 cttgatccaa agtttgtgaa tttggctttg ctacctcaat tgcaggtgtt 2800

 tgtttgcctt tataaactgt tgcaaataga aaaaaaatag aataagtata 2850

 tatttttgga gtaacatcaa tatttaaaca tttttacaca gatcggtgtt 2900

 tgaaaatttg ccatttcagg ctaatatttt tatatatttt tgacttttta 2950

 aaagttcatc agtgtttttg ctactgttaa gcttatgcag tttatactgt 3000

 attttttatg tatcctttat atttaccaaa cctgactccc tgtaaaggag 3050

 tgctgtctta aaaacaactg aaggggttaa agtcgtttct tttagtttaa 3100

 tagatgtgca taaggtagct ttagcaatta aattctagtg aagttgatat 3150

 agtctcattt ttaattgtcc tgtaatggaa cagtagcaaa ttcactaaac 3200

 ttttgtgttc agagttaaat tgttctcagt actttcaatg taggggaatg 3250

 taataaacat agtgtgtatg tttgggtttt aattacacat tttatatatg 3300

 agccatttag atatgcagtg ttaattctat actgcatttg aagtgtatgt 3350

 aacttagctt atgttaatgc agtcatgaag ttggtttgct ccagcatccg 3400

 gtagtcttta aacattcttt tagtgaaatt gtcattgttt tatcagtgct 3450

 aatgtgtgca agcagttttt ttattttgct tttctcctgg catcagaaag 3500

 tggtggcgtt ttctgtactg gattgcacca aggaagcttt tggggaggaa 3550

 ggaaggacat taaattcttt ccctggtaat gaaaagagcc ctttatcaat 3600

 acagtgctgc aatttctgga tatcagctac actttgtttt taagtttgtt 3650

 tttgacatgt ttatttggca aattttataa tgaagtttta agttgaaaat 3700

 aaaatgtagc aaca 3714

<210> 448
<211> 615
<212> PRT
<213> Homo sapien

<400> 448
 Met Pro Ser Arg Lys Phe Ala Asp Gly Glu Val Val Arg Gly Arg
   1               5                  10                  15

 Trp Pro Gly Ser Ser Leu Tyr Tyr Glu Val Glu Ile Leu Ser His
                  20                  25                  30

 Asp Ser Thr Ser Gln Leu Tyr Thr Val Lys Tyr Lys Asp Gly Thr
                  35                  40                  45

 Glu Leu Glu Leu Lys Glu Asn Asp Ile Lys Pro Leu Thr Ser Phe
                  50                  55                  60

 Arg Gln Arg Lys Gly Gly Ser Thr Ser Ser Ser Pro Ser Arg Arg
                  65                  70                  75

 Arg Gly Ser Arg Ser Arg Ser Arg Ser Arg Ser Pro Gly Arg Pro
                  80                  85                  90

 Pro Lys Ser Ala Arg Arg Ser Ala Ser Ala Ser His Gln Ala Asp
                  95                 100                 105

 Ile Lys Glu Ala Arg Arg Glu Val Glu Val Lys Leu Thr Pro Leu
                 110                 115                 120

 Ile Leu Lys Pro Phe Gly Asn Ser Ile Ser Arg Tyr Asn Gly Glu
                 125                 130                 135

 Pro Glu His Ile Glu Arg Asn Asp Ala Pro His Lys Asn Thr Gln
                 140                 145                 150

 Glu Lys Phe Ser Leu Ser Gln Glu Ser Ser Tyr Ile Ala Thr Gln
                 155                 160                 165

 Tyr Ser Leu Arg Pro Arg Arg Glu Glu Val Lys Leu Lys Glu Ile
                 170                 175                 180

 Asp Ser Lys Glu Glu Lys Tyr Val Ala Lys Glu Leu Ala Val Arg
                 185                 190                 195

 Thr Phe Glu Val Thr Pro Ile Arg Ala Lys Asp Leu Glu Phe Gly
                 200                 205                 210

 Gly Val Pro Gly Val Phe Leu Ile Met Phe Gly Leu Pro Val Phe
                 215                 220                 225

 Leu Phe Leu Leu Leu Leu Met Cys Lys Gln Lys Asp Pro Ser Leu
                 230                 235                 240

 Leu Asn Phe Pro Pro Pro Leu Pro Ala Leu Tyr Glu Leu Trp Glu
                 245                 250                 255

 Thr Arg Val Phe Gly Val Tyr Leu Leu Trp Phe Leu Ile Gln Val
                 260                 265                 270

 Leu Phe Tyr Leu Leu Pro Ile Gly Lys Val Val Glu Gly Thr Pro
                 275                 280                 285

 Leu Ile Asp Gly Arg Arg Leu Lys Tyr Arg Leu Asn Gly Phe Tyr
                 290                 295                 300

 Pro Phe Ile Leu Thr Ser Ala Val Ile Gly Thr Ser Leu Phe Gln
                 305                 310                 315

 Gly Val Glu Phe His Tyr Val Tyr Ser His Phe Leu Gln Phe Ala
                 320                 325                 330

 Leu Ala Ala Thr Val Phe Cys Val Val Leu Ser Val Tyr Leu Tyr
                 335                 340                 345

 Met Arg Ser Leu Lys Ala Pro Arg Asn Asp Leu Ser Pro Ala Ser
                 350                 355                 360

 Ser Gly Asn Ala Val Tyr Asp Phe Phe Ile Gly Arg Glu Leu Asn
                 365                 370                 375

 Pro Arg Ile Gly Thr Phe Asp Leu Lys Tyr Phe Cys Glu Leu Arg
                 380                 385                 390

 Pro Gly Leu Ile Gly Trp Val Val Ile Asn Leu Val Met Leu Leu
                 395                 400                 405

 Ala Glu Met Lys Ile Gln Asp Arg Ala Val Pro Ser Leu Ala Met
                 410                 415                 420

 Ile Leu Val Asn Ser Phe Gln Leu Leu Tyr Val Val Asp Ala Leu
                 425                 430                 435

 Trp Asn Glu Glu Ala Leu Leu Thr Thr Met Asp Ile Ile His Asp
                 440                 445                 450

 Gly Phe Gly Phe Met Leu Ala Phe Gly Asp Leu Val Trp Val Pro
                 455                 460                 465

 Phe Ile Tyr Ser Phe Gln Ala Phe Tyr Leu Val Ser His Pro Asn
                 470                 475                 480

 Glu Val Ser Trp Pro Met Ala Ser Leu Ile Ile Val Leu Lys Leu
                 485                 490                 495

 Cys Gly Tyr Val Ile Phe Arg Gly Ala Asn Ser Gln Lys Asn Ala
                 500                 505                 510

 Phe Arg Lys Asn Pro Ser Asp Pro Lys Leu Ala His Leu Lys Thr
                 515                 520                 525

 Ile His Thr Ser Ser Gly Lys Asn Leu Leu Val Ser Gly Trp Trp
                 530                 535                 540

 Gly Phe Val Arg His Pro Asn Tyr Leu Gly Asp Leu Ile Met Ala
                 545                 550                 555

 Leu Ala Trp Ser Leu Pro Cys Gly Phe Asn His Ile Leu Pro Tyr
                 560                 565                 570

 Phe Tyr Ile Ile Tyr Phe Thr Met Leu Leu Val His Arg Glu Ala
                 575                 580                 585

 Arg Asp Glu Tyr His Cys Lys Lys Lys Tyr Gly Val Ala Trp Glu
                 590                 595                 600

 Lys Tyr Cys Gln Arg Val Pro Tyr Arg Ile Phe Pro Tyr Ile Tyr
                 605                 610                 615

<210> 449
<211> 4092
<212> DNA
<213> Homo sapien

<400> 449
 gtcacaaagg ggggaacacg tgggcgccgg ctgccggggc ggcgatctta 50

 gggaactagg gtcacctgga gagccgccca ccgtctctgc ccgctcgact 100

 cctccgcccg ggccgctcgg ccggtccagc cgcggccggc gcctggctgt 150

 gaggtggatt cccggcccag tctgaccatc tccctccagt ttttccactt 200

 cgttcggacc ttctcataac tatgtccacc ctctacgtct cccctcaccc 250

 agatgccttc cccagcctcc gagccctcat agccgctcgc tatggggagg 300

 ctggggaggg tcccggatgg ggaggagccc acccccgcat ctgtctccag 350

 ccacccccga ctagcaggac tccctttccc ccaccccgcc tgccggccct 400

 ggagcagggg cccggtgggc tctgggtgtg gggggccacg gctgtggccc 450

 agctgctgtg gccagcaggc ctggggggcc cagggggcag ccgggcggct 500

 gtccttgtcc aacagtgggt cagttacgcc gacacggagt taataccagc 550

 tgcctgtgga gcaacgctgc cggccctggg actccgaagc tcggcccagg 600

 acccccaggc tgtgctgggg gccctgggca gggccctgag ccccttggag 650

 gagtggcttc ggctgcacac ctacttggcc ggggaggccc ccactctggc 700

 tgacctggcg gctgtcacag ccttgctgct gcctttccga tacgtcctag 750

 acccacctgc ccgccggatc tggaataatg tgactcgctg gtttgtcacg 800

 tgtgtccggc agccagaatt ccgagccgtg ctaggagaag tggttctata 850

 ctcaggagcc aggcctctct ctcatcagcc aggccccgag gctcctgccc 900

 tcccaaagac agctgctcag ctcaagaaag aggcaaagaa acgggagaag 950

 ctagagaaat tccaacagaa gcagaagatc caacagcagc agccacctcc 1000

 aggggagaag aaaccaaaac cagagaagag ggagaaacgg gatcctgggg 1050

 tcattaccta tgacctccca accccacccg gggaaaagaa agatgtcagt 1100

 ggccccatgc ccgactccta cagccctcgg tatgtggagg ctgcctggta 1150

 cccttggtgg gagcagcagg gcttcttcaa gccagagtat gggcgtccta 1200

 atgtgtcagc agcaaatccc cgaggtgtct tcatgatgtg catcccaccc 1250

 cccaatgtga caggctccct gcacctgggc catgcactca ccaacgccat 1300

 ccaggactcc ctgactcgat ggcaccgcat gcgtggggag accaccctgt 1350

 ggaaccctgg ctgtgaccat gcaggtattg ccacccaggt ggtggtggag 1400

 aagaagctat ggcgtgagca gggactgagc cggcaccagc tgggccgcga 1450

 ggcctttcta caggaagtct ggaagtggaa ggaggagaaa ggtgaccgga 1500

 tttaccacca gttgaagaag cttggcagct ccttggactg ggatcgagcc 1550

 tgtttcacca tggaccctaa actctcagca gctgtgacag aggcctttgt 1600

 ccggcttcac gaggaaggca tcatctatcg cagtacccgc cttgttaact 1650

 ggtcctgcac cctcaactcc gccatctctg acattgaggt ggataagaag 1700

 gagctgacag gtcgcaccct gctctccgtg cctggctaca aggagaaggt 1750

 ggagttcggg gtcctcgtgt cctttgccta taaggtccaa ggctcagata 1800

 gcgacgagga ggtggtggtg gcaacaactc ggatcgagac aatgctggga 1850

 gatgtggctg tagctgtgca ccccaaagat accagatacc agcacctgaa 1900

 ggggaagaac gtgatccacc cattcctgtc tcggagcctt cccattgtct 1950

 tcgatgaatt tgtggacatg gactttggca caggtgctgt gaagatcacc 2000

 cccgcacatg accaaaatga ctatgaagtt gggcagcggc acgggctgga 2050

 ggccatcagc atcatggact cccggggggc cctcatcaat gtgcctccgc 2100

 ctttcctggg cctgcccagg tttgaggcca ggaaagcggt gctggtggcg 2150

 ctgaaggagc ggggactgtt ccgtggcatt gaggacaacc ccatggtggt 2200

 gccactttgc aaccggtcga aggacgtggt agagcctctg ctgcggccgc 2250

 agtggtacgt tcgctgcggg gagatggccc aggctgccag cgccgctgtg 2300

 actcggggtg acctccgcat cctgcctgag gcccatcagc gcacatggca 2350

 tgcctggatg gacaacatcc gggagtggtg catttccagg cagctgtggt 2400

 ggggccatcg catcccagcc tactttgtca ctgtcagtga cccagcggtg 2450

 ccccctgggg aggaccctga tgggcggtac tgggtgagtg gacgcaatga 2500

 ggcggaggcc cgggagaagg cagccaagga gttcggagtg tcccctgaca 2550

 agatcagtct ccagcaagat gaggatgtat tggatacctg gttctcctct 2600

 ggcctcttcc ccttatccat tttgggctgg cccaaccagt cagaagacct 2650

 gagtgtgttc taccccggga cactgctgga gaccggtcat gacatcctct 2700

 tcttctgggt ggcccggatg gtcatgctgg gcctgaagct cacgggcagg 2750

 ctgcccttta gagaggtcta cctccatgcc atcgtgcgag atgctcacgg 2800

 ccggaagatg agcaagtctc taggcaatgt catcgatccc ctggatgtca 2850

 tctatggaat ctccctgcag ggcctccaca accagctgct gaacagcaac 2900

 ctggatccca gcgaggtgga gaaggccaaa gaagggcaga aagctgactt 2950

 cccagcgggg attcctgaat gtggcaccga tgctctccgg tttggattat 3000

 gtgcctacat gtcccagggt cgtgacatca acctggatgt gaaccggata 3050

 ctgggttacc gccacttctg caacaagctc tggaatgcca ccaagtttgc 3100

 ccttcgtggc cttgggaagg gttttgtgcc ctcacccacc tcccagcccg 3150

 gaggccatga gagcctggtg gaccgctgga tccgcagccg cctgacagag 3200

 gctgtgaggc tcagcaatca aggcttccag gcctacgact tcccggccgt 3250

 caccactgcc cagtacagct tctggctcta tgagctctgt gatgtctact 3300

 tggagtgcct gaaacctgta ctgaatgggg tggaccaggt ggcagctgag 3350

 tgtgcccgcc agaccctgta cacttgcctg gacgttggcc tgcggctgct 3400

 ctcacccttc atgcccttcg tgacggagga gctgttccag aggctgcccc 3450

 ggaggatgcc gcaagctccc cctagcctct gtgttacccc ctacccggag 3500

 ccctcagagt gctcctggaa ggaccccgag gcagaagccg cccttgagct 3550

 ggcgctaagc atcacgcgag ccgtgcgctc cctgcgggcc gactacaacc 3600

 tcacccggat ccggcctgac tgtttcctgg aagtggcgga tgaggccacg 3650

 ggcgccctgg catcggcggt gtcgggctac gtgcaggccc tggccagcgc 3700

 aggtgtggtg gctgttctgg ccctgggggc tcccgccccc cagggttgcg 3750

 ctgtggctct ggcttctgat cgctgctcca tccacctgca gcttcagggg 3800

 ctggtggacc ctgcacggga gctgggcaag ctgcaagcca agcgagttga 3850

 ggcccagcgg caggcccagc gtctgcggga acgccgtgct gcctcgggct 3900

 atcctgtcaa ggtgccgctc gaagtccagg aggcagatga agccaagctc 3950

 caacagacag aagcagagct caggaaggtg gatgaggcca tcgccctatt 4000

 ccagaagatg ctgtgatcca ccacccagct tcacccctca cccccagcgg 4050

 ctcaccatgg ggatggcagc aataaaatat tttcccacaa aa 4092

<210> 450
<211> 1264
<212> PRT
<213> Homo sapien

<400> 450
 Met Ser Thr Leu Tyr Val Ser Pro His Pro Asp Ala Phe Pro Ser
   1               5                  10                  15

 Leu Arg Ala Leu Ile Ala Ala Arg Tyr Gly Glu Ala Gly Glu Gly
                  20                  25                  30

 Pro Gly Trp Gly Gly Ala His Pro Arg Ile Cys Leu Gln Pro Pro
                  35                  40                  45

 Pro Thr Ser Arg Thr Pro Phe Pro Pro Pro Arg Leu Pro Ala Leu
                  50                  55                  60

 Glu Gln Gly Pro Gly Gly Leu Trp Val Trp Gly Ala Thr Ala Val
                  65                  70                  75

 Ala Gln Leu Leu Trp Pro Ala Gly Leu Gly Gly Pro Gly Gly Ser
                  80                  85                  90

 Arg Ala Ala Val Leu Val Gln Gln Trp Val Ser Tyr Ala Asp Thr
                  95                 100                 105

 Glu Leu Ile Pro Ala Ala Cys Gly Ala Thr Leu Pro Ala Leu Gly
                 110                 115                 120

 Leu Arg Ser Ser Ala Gln Asp Pro Gln Ala Val Leu Gly Ala Leu
                 125                 130                 135

 Gly Arg Ala Leu Ser Pro Leu Glu Glu Trp Leu Arg Leu His Thr
                 140                 145                 150

 Tyr Leu Ala Gly Glu Ala Pro Thr Leu Ala Asp Leu Ala Ala Val
                 155                 160                 165

 Thr Ala Leu Leu Leu Pro Phe Arg Tyr Val Leu Asp Pro Pro Ala
                 170                 175                 180

 Arg Arg Ile Trp Asn Asn Val Thr Arg Trp Phe Val Thr Cys Val
                 185                 190                 195

 Arg Gln Pro Glu Phe Arg Ala Val Leu Gly Glu Val Val Leu Tyr
                 200                 205                 210

 Ser Gly Ala Arg Pro Leu Ser His Gln Pro Gly Pro Glu Ala Pro
                 215                 220                 225

 Ala Leu Pro Lys Thr Ala Ala Gln Leu Lys Lys Glu Ala Lys Lys
                 230                 235                 240

 Arg Glu Lys Leu Glu Lys Phe Gln Gln Lys Gln Lys Ile Gln Gln
                 245                 250                 255

 Gln Gln Pro Pro Pro Gly Glu Lys Lys Pro Lys Pro Glu Lys Arg
                 260                 265                 270

 Glu Lys Arg Asp Pro Gly Val Ile Thr Tyr Asp Leu Pro Thr Pro
                 275                 280                 285

 Pro Gly Glu Lys Lys Asp Val Ser Gly Pro Met Pro Asp Ser Tyr
                 290                 295                 300

 Ser Pro Arg Tyr Val Glu Ala Ala Trp Tyr Pro Trp Trp Glu Gln
                 305                 310                 315

 Gln Gly Phe Phe Lys Pro Glu Tyr Gly Arg Pro Asn Val Ser Ala
                 320                 325                 330

 Ala Asn Pro Arg Gly Val Phe Met Met Cys Ile Pro Pro Pro Asn
                 335                 340                 345

 Val Thr Gly Ser Leu His Leu Gly His Ala Leu Thr Asn Ala Ile
                 350                 355                 360

 Gln Asp Ser Leu Thr Arg Trp His Arg Met Arg Gly Glu Thr Thr
                 365                 370                 375

 Leu Trp Asn Pro Gly Cys Asp His Ala Gly Ile Ala Thr Gln Val
                 380                 385                 390

 Val Val Glu Lys Lys Leu Trp Arg Glu Gln Gly Leu Ser Arg His
                 395                 400                 405

 Gln Leu Gly Arg Glu Ala Phe Leu Gln Glu Val Trp Lys Trp Lys
                 410                 415                 420

 Glu Glu Lys Gly Asp Arg Ile Tyr His Gln Leu Lys Lys Leu Gly
                 425                 430                 435

 Ser Ser Leu Asp Trp Asp Arg Ala Cys Phe Thr Met Asp Pro Lys
                 440                 445                 450

 Leu Ser Ala Ala Val Thr Glu Ala Phe Val Arg Leu His Glu Glu
                 455                 460                 465

 Gly Ile Ile Tyr Arg Ser Thr Arg Leu Val Asn Trp Ser Cys Thr
                 470                 475                 480

 Leu Asn Ser Ala Ile Ser Asp Ile Glu Val Asp Lys Lys Glu Leu
                 485                 490                 495

 Thr Gly Arg Thr Leu Leu Ser Val Pro Gly Tyr Lys Glu Lys Val
                 500                 505                 510

 Glu Phe Gly Val Leu Val Ser Phe Ala Tyr Lys Val Gln Gly Ser
                 515                 520                 525

 Asp Ser Asp Glu Glu Val Val Val Ala Thr Thr Arg Ile Glu Thr
                 530                 535                 540

 Met Leu Gly Asp Val Ala Val Ala Val His Pro Lys Asp Thr Arg
                 545                 550                 555

 Tyr Gln His Leu Lys Gly Lys Asn Val Ile His Pro Phe Leu Ser
                 560                 565                 570

 Arg Ser Leu Pro Ile Val Phe Asp Glu Phe Val Asp Met Asp Phe
                 575                 580                 585

 Gly Thr Gly Ala Val Lys Ile Thr Pro Ala His Asp Gln Asn Asp
                 590                 595                 600

 Tyr Glu Val Gly Gln Arg His Gly Leu Glu Ala Ile Ser Ile Met
                 605                 610                 615

 Asp Ser Arg Gly Ala Leu Ile Asn Val Pro Pro Pro Phe Leu Gly
                 620                 625                 630

 Leu Pro Arg Phe Glu Ala Arg Lys Ala Val Leu Val Ala Leu Lys
                 635                 640                 645

 Glu Arg Gly Leu Phe Arg Gly Ile Glu Asp Asn Pro Met Val Val
                 650                 655                 660

 Pro Leu Cys Asn Arg Ser Lys Asp Val Val Glu Pro Leu Leu Arg
                 665                 670                 675

 Pro Gln Trp Tyr Val Arg Cys Gly Glu Met Ala Gln Ala Ala Ser
                 680                 685                 690

 Ala Ala Val Thr Arg Gly Asp Leu Arg Ile Leu Pro Glu Ala His
                 695                 700                 705

 Gln Arg Thr Trp His Ala Trp Met Asp Asn Ile Arg Glu Trp Cys
                 710                 715                 720

 Ile Ser Arg Gln Leu Trp Trp Gly His Arg Ile Pro Ala Tyr Phe
                 725                 730                 735

 Val Thr Val Ser Asp Pro Ala Val Pro Pro Gly Glu Asp Pro Asp
                 740                 745                 750

 Gly Arg Tyr Trp Val Ser Gly Arg Asn Glu Ala Glu Ala Arg Glu
                 755                 760                 765

 Lys Ala Ala Lys Glu Phe Gly Val Ser Pro Asp Lys Ile Ser Leu
                 770                 775                 780

 Gln Gln Asp Glu Asp Val Leu Asp Thr Trp Phe Ser Ser Gly Leu
                 785                 790                 795

 Phe Pro Leu Ser Ile Leu Gly Trp Pro Asn Gln Ser Glu Asp Leu
                 800                 805                 810

 Ser Val Phe Tyr Pro Gly Thr Leu Leu Glu Thr Gly His Asp Ile
                 815                 820                 825

 Leu Phe Phe Trp Val Ala Arg Met Val Met Leu Gly Leu Lys Leu
                 830                 835                 840

 Thr Gly Arg Leu Pro Phe Arg Glu Val Tyr Leu His Ala Ile Val
                 845                 850                 855

 Arg Asp Ala His Gly Arg Lys Met Ser Lys Ser Leu Gly Asn Val
                 860                 865                 870

 Ile Asp Pro Leu Asp Val Ile Tyr Gly Ile Ser Leu Gln Gly Leu
                 875                 880                 885

 His Asn Gln Leu Leu Asn Ser Asn Leu Asp Pro Ser Glu Val Glu
                 890                 895                 900

 Lys Ala Lys Glu Gly Gln Lys Ala Asp Phe Pro Ala Gly Ile Pro
                 905                 910                 915

 Glu Cys Gly Thr Asp Ala Leu Arg Phe Gly Leu Cys Ala Tyr Met
                 920                 925                 930

 Ser Gln Gly Arg Asp Ile Asn Leu Asp Val Asn Arg Ile Leu Gly
                 935                 940                 945

 Tyr Arg His Phe Cys Asn Lys Leu Trp Asn Ala Thr Lys Phe Ala
                 950                 955                 960

 Leu Arg Gly Leu Gly Lys Gly Phe Val Pro Ser Pro Thr Ser Gln
                 965                 970                 975

 Pro Gly Gly His Glu Ser Leu Val Asp Arg Trp Ile Arg Ser Arg
                 980                 985                 990

 Leu Thr Glu Ala Val Arg Leu Ser Asn Gln Gly Phe Gln Ala Tyr
                 995                1000                1005

 Asp Phe Pro Ala Val Thr Thr Ala Gln Tyr Ser Phe Trp Leu Tyr
                1010                1015                1020

 Glu Leu Cys Asp Val Tyr Leu Glu Cys Leu Lys Pro Val Leu Asn
                1025                1030                1035

 Gly Val Asp Gln Val Ala Ala Glu Cys Ala Arg Gln Thr Leu Tyr
                1040                1045                1050

 Thr Cys Leu Asp Val Gly Leu Arg Leu Leu Ser Pro Phe Met Pro
                1055                1060                1065

 Phe Val Thr Glu Glu Leu Phe Gln Arg Leu Pro Arg Arg Met Pro
                1070                1075                1080

 Gln Ala Pro Pro Ser Leu Cys Val Thr Pro Tyr Pro Glu Pro Ser
                1085                1090                1095

 Glu Cys Ser Trp Lys Asp Pro Glu Ala Glu Ala Ala Leu Glu Leu
                1100                1105                1110

 Ala Leu Ser Ile Thr Arg Ala Val Arg Ser Leu Arg Ala Asp Tyr
                1115                1120                1125

 Asn Leu Thr Arg Ile Arg Pro Asp Cys Phe Leu Glu Val Ala Asp
                1130                1135                1140

 Glu Ala Thr Gly Ala Leu Ala Ser Ala Val Ser Gly Tyr Val Gln
                1145                1150                1155

 Ala Leu Ala Ser Ala Gly Val Val Ala Val Leu Ala Leu Gly Ala
                1160                1165                1170

 Pro Ala Pro Gln Gly Cys Ala Val Ala Leu Ala Ser Asp Arg Cys
                1175                1180                1185

 Ser Ile His Leu Gln Leu Gln Gly Leu Val Asp Pro Ala Arg Glu
                1190                1195                1200

 Leu Gly Lys Leu Gln Ala Lys Arg Val Glu Ala Gln Arg Gln Ala
                1205                1210                1215

 Gln Arg Leu Arg Glu Arg Arg Ala Ala Ser Gly Tyr Pro Val Lys
                1220                1225                1230

 Val Pro Leu Glu Val Gln Glu Ala Asp Glu Ala Lys Leu Gln Gln
                1235                1240                1245

 Thr Glu Ala Glu Leu Arg Lys Val Asp Glu Ala Ile Ala Leu Phe
                1250                1255                1260

 Gln Lys Met Leu


<210> 451
<211> 2570
<212> DNA
<213> Homo sapien

<400> 451
 tcggaggagc cagccgaaat cctgccgcct gcccgggacg aggaggagga 50

 ggaggaagag gggatggagc aggggctgga ggaggaagaa gaggtggatc 100

 cccggatcca gggagaactg gagaagttaa atcagtccac ggatgatatc 150

 aacagacggg agactgaact tgaggatgct cgtcagaagt tccgctctgt 200

 tctggttgaa gcaacggtga aactggatga actggtgaag aaaattggca 250

 aagctgtgga agactccaag ccctactggg aggcacggag ggtggcgagg 300

 caggctcagc tggaagctca gaaagccacg caggacttcc agagggccac 350

 agaggtgctc cgtgccgcca aggagaccat ctccctggcc gagcagcggc 400

 tgctggagga tgacaagcgg cagttcgact ccgcctggca ggagatgctg 450

 aatcacgcca ctcagagggt catggaggcg gagcagacca agaccaggag 500

 cgagctggtg cataaggaga cggcagccag gtacaatgcc gccatgggcc 550

 gcatgcgaca gctggagaag aaactcaaga gagccatcaa caagtccaag 600

 ccttattttg aactcaaggc aaagtactat gtgcagctcg agcaactgaa 650

 aaagactgtg gatgacctgc aggccaaact gaccctggca aaaggcgagt 700

 acaagatggc cctgaagaac ctggagatga tctcagatga gatccacgag 750

 cggcggcgct ccagtgccat ggggcctcgg ggatgcggtg ttggtgctga 800

 gggcagcagc acatctgtgg aggatctgcc agggagcaaa cctgagcctg 850

 atgccatttc tgtggcctcg gaggcctttg aagatgacag ctgtagcaac 900

 tttgtgtctg aagatgactc ggaaacccag tccgtgtcca gctttagttc 950

 aggaccaaca agcccgtctg agatgcctga ccagttccct gcggttgtga 1000

 ggcctggcag cctggatctg cccagccctg tgtccctgtc agagtttggg 1050

 atgatgttcc cagtgttggg ccctcgaagt gaatgcagcg gggcctcctc 1100

 ccctgaatgt gaagtagaac gaggagacag ggcagaaggg gcagagaata 1150

 aaacaagtga caaagccaac aacaaccggg gcctcagcag tagcagtggc 1200

 agtggtggca gcagtaagag ccaaagcagc acctcccctg agggccaggc 1250

 cttggagaac cggatgaagc agctctccct acagtgctca aagggaagag 1300

 atggaattat tgctgacata aaaatggtgc agattggctg attcatcctg 1350

 ggccctggcc gatgtgcata tcaacattta tacatggaac tggagaacat 1400

 tgtgccaata atcatttaat atatgccaaa tcttacacgt ctactctaaa 1450

 ctgctctaat gaagtttcag tgaccttgag ggctaaagat tgttcttctg 1500

 ggtaagagct cttgggctgg tttttcagag cagagttctt gttgtgggta 1550

 gactgtgact aggttcacag cctttgtgga acattccgta taacggcatt 1600

 gtggaagcaa taactagttc ctatgaaaga accagagctg ggaagatggc 1650

 tgggaagcca ggccaaagtg ggggcaacag cttgcttctc tttctcttct 1700

 caccctcagt ttgtatggga aaatggagat gtcctctcca ctttatccca 1750

 cgatatctaa atgaaaaaga aagaaaaccc acacacaaag caaaaactca 1800

 agtattaaga gcacatattt ttgacccagt ggaggcttaa aaaaaaaaaa 1850

 atccaagaac acaattcatt ttcaccacct ctggtgttca gagggggctt 1900

 ttaaaaaagc gtgtatgctg ggatacccat taaaaccatt ttctagaagg 1950

 ctaccatgag ctgcactttt tggggtggga aaggtgaatg ccagtgggga 2000

 tgcgggggga tgagggtagg agggacttat agaaggggat ttgtggctgt 2050

 gggggagaag gttctacagc ataagcctta tcctgccagc caaggggatt 2100

 tattctaaga gaagtgcatg tgaagaatgg ttgccactgt tattagattg 2150

 acaagatgtt aatttctctg taggttgtaa ctttaaaaat aaatgaaatt 2200

 atttaagggt tatgctgcac tagtattcct tagaggaaac agttctttaa 2250

 agttaggaaa gggagtaggc aggcatgtgt tggcaaaggc tgttaatagt 2300

 agttaagtgt taagactgct tttctttaac gttttcatgg taatgcatat 2350

 ttagagcact gtatttttgt cttgttaaga aaatttagca tttctaaaag 2400

 aaaaaagcaa ccctctttca aactgttaat tctgtcacag cctgtatatt 2450

 ttagtcattt gtaaatctct tcatacaata gtgacttctt ttttgactga 2500

 tacagtatct taattacaag gttattttgt acttgtctta atacactaag 2550

 tgtaataaaa acggcttgag 2570

<210> 452
<211> 425
<212> PRT
<213> Homo sapien

<400> 452
 Met Glu Gln Gly Leu Glu Glu Glu Glu Glu Val Asp Pro Arg Ile
   1               5                  10                  15

 Gln Gly Glu Leu Glu Lys Leu Asn Gln Ser Thr Asp Asp Ile Asn
                  20                  25                  30

 Arg Arg Glu Thr Glu Leu Glu Asp Ala Arg Gln Lys Phe Arg Ser
                  35                  40                  45

 Val Leu Val Glu Ala Thr Val Lys Leu Asp Glu Leu Val Lys Lys
                  50                  55                  60

 Ile Gly Lys Ala Val Glu Asp Ser Lys Pro Tyr Trp Glu Ala Arg
                  65                  70                  75

 Arg Val Ala Arg Gln Ala Gln Leu Glu Ala Gln Lys Ala Thr Gln
                  80                  85                  90

 Asp Phe Gln Arg Ala Thr Glu Val Leu Arg Ala Ala Lys Glu Thr
                  95                 100                 105

 Ile Ser Leu Ala Glu Gln Arg Leu Leu Glu Asp Asp Lys Arg Gln
                 110                 115                 120

 Phe Asp Ser Ala Trp Gln Glu Met Leu Asn His Ala Thr Gln Arg
                 125                 130                 135

 Val Met Glu Ala Glu Gln Thr Lys Thr Arg Ser Glu Leu Val His
                 140                 145                 150

 Lys Glu Thr Ala Ala Arg Tyr Asn Ala Ala Met Gly Arg Met Arg
                 155                 160                 165

 Gln Leu Glu Lys Lys Leu Lys Arg Ala Ile Asn Lys Ser Lys Pro
                 170                 175                 180

 Tyr Phe Glu Leu Lys Ala Lys Tyr Tyr Val Gln Leu Glu Gln Leu
                 185                 190                 195

 Lys Lys Thr Val Asp Asp Leu Gln Ala Lys Leu Thr Leu Ala Lys
                 200                 205                 210

 Gly Glu Tyr Lys Met Ala Leu Lys Asn Leu Glu Met Ile Ser Asp
                 215                 220                 225

 Glu Ile His Glu Arg Arg Arg Ser Ser Ala Met Gly Pro Arg Gly
                 230                 235                 240

 Cys Gly Val Gly Ala Glu Gly Ser Ser Thr Ser Val Glu Asp Leu
                 245                 250                 255

 Pro Gly Ser Lys Pro Glu Pro Asp Ala Ile Ser Val Ala Ser Glu
                 260                 265                 270

 Ala Phe Glu Asp Asp Ser Cys Ser Asn Phe Val Ser Glu Asp Asp
                 275                 280                 285

 Ser Glu Thr Gln Ser Val Ser Ser Phe Ser Ser Gly Pro Thr Ser
                 290                 295                 300

 Pro Ser Glu Met Pro Asp Gln Phe Pro Ala Val Val Arg Pro Gly
                 305                 310                 315

 Ser Leu Asp Leu Pro Ser Pro Val Ser Leu Ser Glu Phe Gly Met
                 320                 325                 330

 Met Phe Pro Val Leu Gly Pro Arg Ser Glu Cys Ser Gly Ala Ser
                 335                 340                 345

 Ser Pro Glu Cys Glu Val Glu Arg Gly Asp Arg Ala Glu Gly Ala
                 350                 355                 360

 Glu Asn Lys Thr Ser Asp Lys Ala Asn Asn Asn Arg Gly Leu Ser
                 365                 370                 375

 Ser Ser Ser Gly Ser Gly Gly Ser Ser Lys Ser Gln Ser Ser Thr
                 380                 385                 390

 Ser Pro Glu Gly Gln Ala Leu Glu Asn Arg Met Lys Gln Leu Ser
                 395                 400                 405

 Leu Gln Cys Ser Lys Gly Arg Asp Gly Ile Ile Ala Asp Ile Lys
                 410                 415                 420

 Met Val Gln Ile Gly
                 425

<210> 453
<211> 2570
<212> DNA
<213> Homo sapien

<400> 453
 tcggaggagc cagccgaaat cctgccgcct gcccgggacg aggaggagga 50

 ggaggaagag gggatggagc aggggctgga ggaggaagaa gaggtggatc 100

 cccggatcca gggagaactg gagaagttaa atcagtccac ggatgatatc 150

 aacagacggg agactgaact tgaggatgct cgtcagaagt tccgctctgt 200

 tctggttgaa gcaacggtga aactggatga actggtgaag aaaattggca 250

 aagctgtgga agactccaag ccctactggg aggcacggag ggtggcgagg 300

 caggctcagc tggaagctca gaaagccacg caggacttcc agagggccac 350

 agaggtgctc cgtgccgcca aggagaccat ctccctggcc gagcagcggc 400

 tgctggagga tgacaagcgg cagttcgact ccgcctggca ggagatgctg 450

 aatcacgcca ctcagagggt catggaggcg gagcagacca agaccaggag 500

 cgagctggtg cataaggaga cggcagccag gtacaatgcc gccatgggcc 550

 gcatgcgaca gctggagaag aaactcaaga gagccatcaa caagtccaag 600

 ccttattttg aactcaaggc aaagtactat gtgcagctcg agcaactgaa 650

 aaagactgtg gatgacctgc aggccaaact gaccctggca aaaggcgagt 700

 acaagatggc cctgaagaac ctggagatga tctcagatga gatccacgag 750

 cggcggcgct ccagtgccat ggggcctcgg ggatgcggtg ttggtgctga 800

 gggcagcagc acatctgtgg aggatctgcc agggagcaaa cctgagcctg 850

 atgccatttc tgtggcctcg gaggcctttg aagatgacag ctgtagcaac 900

 tttgtgtctg aagatgactc ggaaacccag tccgtgtcca gctttagttc 950

 aggaccaaca agcccgtctg agatgcctga ccagttccct gcggttgtga 1000

 ggcctggcag cctggatctg cccagccctg tgtccctgtc agagtttggg 1050

 atgatgttcc cagtgttggg ccctcgaagt gaatgcagcg gggcctcctc 1100

 ccctgaatgt gaagtagaac gaggagacag ggcagaaggg gcagagaata 1150

 aaacaagtga caaagccaac aacaaccggg gcctcagcag tagcagtggc 1200

 agtggtggca gcagtaagag ccaaagcagc acctcccctg agggccaggc 1250

 cttggagaac cggatgaagc agctctccct acagtgctca aagggaagag 1300

 atggaattat tgctgacata aaaatggtgc agattggctg attcatcctg 1350

 ggccctggcc gatgtgcata tcaacattta tacatggaac tggagaacat 1400

 tgtgccaata atcatttaat atatgccaaa tcttacacgt ctactctaaa 1450

 ctgctctaat gaagtttcag tgaccttgag ggctaaagat tgttcttctg 1500

 ggtaagagct cttgggctgg tttttcagag cagagttctt gttgtgggta 1550

 gactgtgact aggttcacag cctttgtgga acattccgta taacggcatt 1600

 gtggaagcaa taactagttc ctatgaaaga accagagctg ggaagatggc 1650

 tgggaagcca ggccaaagtg ggggcaacag cttgcttctc tttctcttct 1700

 caccctcagt ttgtatggga aaatggagat gtcctctcca ctttatccca 1750

 cgatatctaa atgaaaaaga aagaaaaccc acacacaaag caaaaactca 1800

 agtattaaga gcacatattt ttgacccagt ggaggcttaa aaaaaaaaaa 1850

 atccaagaac acaattcatt ttcaccacct ctggtgttca gagggggctt 1900

 ttaaaaaagc gtgtatgctg ggatacccat taaaaccatt ttctagaagg 1950

 ctaccatgag ctgcactttt tggggtggga aaggtgaatg ccagtgggga 2000

 tgcgggggga tgagggtagg agggacttat agaaggggat ttgtggctgt 2050

 gggggagaag gttctacagc ataagcctta tcctgccagc caaggggatt 2100

 tattctaaga gaagtgcatg tgaagaatgg ttgccactgt tattagattg 2150

 acaagatgtt aatttctctg taggttgtaa ctttaaaaat aaatgaaatt 2200

 atttaagggt tatgctgcac tagtattcct tagaggaaac agttctttaa 2250

 agttaggaaa gggagtaggc aggcatgtgt tggcaaaggc tgttaatagt 2300

 agttaagtgt taagactgct tttctttaac gttttcatgg taatgcatat 2350

 ttagagcact gtatttttgt cttgttaaga aaatttagca tttctaaaag 2400

 aaaaaagcaa ccctctttca aactgttaat tctgtcacag cctgtatatt 2450

 ttagtcattt gtaaatctct tcatacaata gtgacttctt ttttgactga 2500

 tacagtatct taattacaag gttattttgt acttgtctta atacactaag 2550

 tgtaataaaa acggcttgag 2570

<210> 454
<211> 425
<212> PRT
<213> Homo sapien

<400> 454
 Met Glu Gln Gly Leu Glu Glu Glu Glu Glu Val Asp Pro Arg Ile
   1               5                  10                  15

 Gln Gly Glu Leu Glu Lys Leu Asn Gln Ser Thr Asp Asp Ile Asn
                  20                  25                  30

 Arg Arg Glu Thr Glu Leu Glu Asp Ala Arg Gln Lys Phe Arg Ser
                  35                  40                  45

 Val Leu Val Glu Ala Thr Val Lys Leu Asp Glu Leu Val Lys Lys
                  50                  55                  60

 Ile Gly Lys Ala Val Glu Asp Ser Lys Pro Tyr Trp Glu Ala Arg
                  65                  70                  75

 Arg Val Ala Arg Gln Ala Gln Leu Glu Ala Gln Lys Ala Thr Gln
                  80                  85                  90

 Asp Phe Gln Arg Ala Thr Glu Val Leu Arg Ala Ala Lys Glu Thr
                  95                 100                 105

 Ile Ser Leu Ala Glu Gln Arg Leu Leu Glu Asp Asp Lys Arg Gln
                 110                 115                 120

 Phe Asp Ser Ala Trp Gln Glu Met Leu Asn His Ala Thr Gln Arg
                 125                 130                 135

 Val Met Glu Ala Glu Gln Thr Lys Thr Arg Ser Glu Leu Val His
                 140                 145                 150

 Lys Glu Thr Ala Ala Arg Tyr Asn Ala Ala Met Gly Arg Met Arg
                 155                 160                 165

 Gln Leu Glu Lys Lys Leu Lys Arg Ala Ile Asn Lys Ser Lys Pro
                 170                 175                 180

 Tyr Phe Glu Leu Lys Ala Lys Tyr Tyr Val Gln Leu Glu Gln Leu
                 185                 190                 195

 Lys Lys Thr Val Asp Asp Leu Gln Ala Lys Leu Thr Leu Ala Lys
                 200                 205                 210

 Gly Glu Tyr Lys Met Ala Leu Lys Asn Leu Glu Met Ile Ser Asp
                 215                 220                 225

 Glu Ile His Glu Arg Arg Arg Ser Ser Ala Met Gly Pro Arg Gly
                 230                 235                 240

 Cys Gly Val Gly Ala Glu Gly Ser Ser Thr Ser Val Glu Asp Leu
                 245                 250                 255

 Pro Gly Ser Lys Pro Glu Pro Asp Ala Ile Ser Val Ala Ser Glu
                 260                 265                 270

 Ala Phe Glu Asp Asp Ser Cys Ser Asn Phe Val Ser Glu Asp Asp
                 275                 280                 285

 Ser Glu Thr Gln Ser Val Ser Ser Phe Ser Ser Gly Pro Thr Ser
                 290                 295                 300

 Pro Ser Glu Met Pro Asp Gln Phe Pro Ala Val Val Arg Pro Gly
                 305                 310                 315

 Ser Leu Asp Leu Pro Ser Pro Val Ser Leu Ser Glu Phe Gly Met
                 320                 325                 330

 Met Phe Pro Val Leu Gly Pro Arg Ser Glu Cys Ser Gly Ala Ser
                 335                 340                 345

 Ser Pro Glu Cys Glu Val Glu Arg Gly Asp Arg Ala Glu Gly Ala
                 350                 355                 360

 Glu Asn Lys Thr Ser Asp Lys Ala Asn Asn Asn Arg Gly Leu Ser
                 365                 370                 375

 Ser Ser Ser Gly Ser Gly Gly Ser Ser Lys Ser Gln Ser Ser Thr
                 380                 385                 390

 Ser Pro Glu Gly Gln Ala Leu Glu Asn Arg Met Lys Gln Leu Ser
                 395                 400                 405

 Leu Gln Cys Ser Lys Gly Arg Asp Gly Ile Ile Ala Asp Ile Lys
                 410                 415                 420

 Met Val Gln Ile Gly
                 425

<210> 455
<211> 1645
<212> DNA
<213> Homo sapien

<400> 455
 agtcaagatg gaggagtacg cgcgagagcc ttgcccatgg cgaattgtgg 50

 atgactgtgg tggggccttt acgatgggta ccattggtgg tggtatcttt 100

 caagcaatca aaggttttcg caattctcca gtgggagtaa accacagact 150

 acgagggagt ttgacagcta ttaaaaccag ggctccacag ttaggaggta 200

 gctttgcagt ttggggaggg ctgttttcca tgattgactg tagtatggtt 250

 caagtcagag gaaaggaaga tccctggaac tccatcacaa gtggtgcctt 300

 aacgggagcc atactggcag caagaaatgg accagtggcc atggttgggt 350

 cagccgcaat gggtggcatt ctcctagctt taattgaagg agctggtatc 400

 ttgttgacaa gatttgcctc tgcacagttt cccaatggtc ctcagtttgc 450

 agaagacccc tcccagttgc cttcaactca gttaccttcc tcaccttttg 500

 gagactatcg acaatatcag taggacttct ttcctaggat ttctttaaca 550

 gaacgagttg tggttcgaga aggatttcag aagatcaagt tacagtctgt 600

 ttttaaaacc ataggtggga cagctatggc caataggcta taaagagaca 650

 tttagcactt ttttctattt aaaggaacaa gcggggaagg gtgctaaaag 700

 ataatacgtt tatttattca cacttgaatt gcatttgtga tcaaaataaa 750

 tgtttaaatc gctaaaggaa aatacagtaa gtgcttgaaa gatgaaggac 800

 caaaaggcca aaaaacagtg aaatatgatc atcatctctt gcggacttct 850

 ctgcctggtt ttgtgtgttc tgttattcaa acaataaaaa gctggtggaa 900

 cttactcttt cttttaagat aagttgtaga cttcgatgtt tcatgctcat 950

 gtacttcaaa taatgcatgt tttatagtta gtccctcatc acttgaagtg 1000

 acttctgaga attatgcaga gtcaacatgg atcatttcac agtgagatgc 1050

 tttatggatt gaaggatatg gtaaaatgtt tatagtttac tttgaaagta 1100

 aaatatacta tgtcttggtt ttgaggatat tggatacaaa actctcttcc 1150

 tttagggcta ctgagtcttg attcctgatc atcagaaatt tcaccagaaa 1200

 caacttgctt ccaatatacc caattctata tgaagaattc atggagagtg 1250

 tactggcact ggaagagttt agtgtttctt gtatgcttga aaataaagta 1300

 tgtactgttt tgaatgtgtt ccaagtcctc tgcataaacg atgtattttg 1350

 gggtctggtt gggcctggaa aatggatgag cacttcagaa caggtcattt 1400

 tcctgatatt ggaagtgaca tgtggcccta taggaggcat gatgttagtt 1450

 aattacacat ttgcctacat ctgtgggaaa tggagaacaa agccatgtgg 1500

 gtactgtaaa cacacgttta tcttttggcc caatgccata catatggtag 1550

 gcatttaatt actgattgtg tttggataat ttgggaattt tcgactgtgg 1600

 taaaatatac ataaaataat acttattaaa aaaaaaaaaa aaaaa 1645

<210> 456
<211> 171
<212> PRT
<213> Homo sapien

<400> 456
 Met Glu Glu Tyr Ala Arg Glu Pro Cys Pro Trp Arg Ile Val Asp
   1               5                  10                  15

 Asp Cys Gly Gly Ala Phe Thr Met Gly Thr Ile Gly Gly Gly Ile
                  20                  25                  30

 Phe Gln Ala Ile Lys Gly Phe Arg Asn Ser Pro Val Gly Val Asn
                  35                  40                  45

 His Arg Leu Arg Gly Ser Leu Thr Ala Ile Lys Thr Arg Ala Pro
                  50                  55                  60

 Gln Leu Gly Gly Ser Phe Ala Val Trp Gly Gly Leu Phe Ser Met
                  65                  70                  75

 Ile Asp Cys Ser Met Val Gln Val Arg Gly Lys Glu Asp Pro Trp
                  80                  85                  90

 Asn Ser Ile Thr Ser Gly Ala Leu Thr Gly Ala Ile Leu Ala Ala
                  95                 100                 105

 Arg Asn Gly Pro Val Ala Met Val Gly Ser Ala Ala Met Gly Gly
                 110                 115                 120

 Ile Leu Leu Ala Leu Ile Glu Gly Ala Gly Ile Leu Leu Thr Arg
                 125                 130                 135

 Phe Ala Ser Ala Gln Phe Pro Asn Gly Pro Gln Phe Ala Glu Asp
                 140                 145                 150

 Pro Ser Gln Leu Pro Ser Thr Gln Leu Pro Ser Ser Pro Phe Gly
                 155                 160                 165

 Asp Tyr Arg Gln Tyr Gln
                 170

<210> 457
<211> 3236
<212> DNA
<213> Homo sapien

<400> 457
 ctccaccgcg gcgagaggca tgggcacgtg gctgccgagg gtggccgagc 50

 tctgggaaga aaagcccgtg tgcctctgca tagcgtcgct acagcgctga 100

 ctcggtgtgg attgattgga aaggtttgag ggagtacttg ggaagcatgg 150

 tggcacatga tgagactgga ggtctcctac ctattaaaag gaccatacga 200

 gtcctagatg tcaataacca gtccttcaga gaacaagagg agccaagcaa 250

 taaaagagtt cgacctctgg ctcgtgtcac gtccttggca aatttaatct 300

 ctcctgtaag aaatggagct gtcagacgtt ttggtcaaac aatacagtca 350

 tttacccttc gtggtgacca cagatcccca gcctctgccc agaagttttc 400

 tagcaggtca acagtcccaa cacccgccaa gagaaggagc agtgcactgt 450

 ggtcagagat gctggacatc accatgaagg agtctctcac caccagggag 500

 atcagacggc aggaggcaat atatgaaatg tcccgaggtg aacaggattt 550

 aattgaggat ctcaaacttg caagaaaggc ctaccatgac cccatgttaa 600

 agttgtccat catgtcagaa gaggaactca cacatatatt tggtgatctg 650

 gactcttaca tacctctgca tgaagatttg ttgacaagaa taggagaagc 700

 aaccaagcct gatggaacag tggagcagat tggtcacatt ctcgtgagct 750

 ggttaccgcg cttgaatgcc tacagaggtt actgtagtaa ccagctggca 800

 gccaaagctc ttcttgatca aaagaaacag gatccaagag tccaagactt 850

 cctccagcga tgtctcgagt ctcccttcag tcgaaaacta gatctttgga 900

 gtttcctaga tatccctcga agtcgcctag tcaaataccc tttactgtta 950

 aaagaaattc ttaaacacac tccaaaagag caccctgatg ttcagcttct 1000

 ggaggatgct atattgataa tacagggagt cctctctgat atcaacttga 1050

 agaaaggtga atccgagtgc cagtattaca tcgacaagct ggagtacctg 1100

 gatgaaaagc agagggaccc cagaatcgaa gcgagcaaag tgctgctgtg 1150

 ccatggggag ctgcggagca agagtggaca taaactttac attttcctgt 1200

 ttcaagacat cttggttctg actcggcccg tcacacggaa cgaacggcac 1250

 tcttaccagg tttaccggca gccaatccca gtccaagagc tagtcctaga 1300

 agacctgcag gatggagatg tgagaatggg aggctccttt cgaggagctt 1350

 tcagtaactc agagaaagct aaaaatatct ttagaattcg cttccatgac 1400

 ccctctccag cccagtctca cactctgcaa gccaatgacg tgttccacaa 1450

 gcagcagtgg ttcaactgta ttcgagcggc cattgccccc ttccagtcgg 1500

 caggcagtcc acctgagctg cagggcctgc cggagctgca cgaagagtgt 1550

 gaggggaacc acccctctgc gaggaaactc acagcccaga ggagggcatc 1600

 cacagtttcc agtgttactc aggtagaagt tgatgaaaac gcttacagat 1650

 gtggctctgg catgcagatg gcagaggaca gcaagagctt aaagacacac 1700

 cagacacagc ccggcatccg aagagcgagg gacaaagccc tttctggtgg 1750

 caaacggaaa gagactttgg tgtagagaag gctctgtgtg ttaactgatg 1800

 ggagagactg tttgtttata aatgtgtaca gttttgtttt ctcgtaaggg 1850

 gagcatcata gggttacttt ataccagttg taacattttc attgtttttg 1900

 gttgttcttt tttctttttt taatggcagc taaagatata cagattactg 1950

 ttaaattgca gtcctttttt tttttaaaga tattttcttg aattatttag 2000

 aacatggtaa gcctggtatt ttttaatcaa acaaaatatt tatgaaatgg 2050

 gttttctctt aattctggat tcatcatggc tttctaatac caattgtaat 2100

 atttacaata ttcaccaaaa cttagaattt tgcaaatgct ggaattctgc 2150

 cagtgtttct ttgctaagcc ttgcatgcaa aatttgaaat tttaacattg 2200

 gcacccaaaa cctacatgga atgtatgtct ggagtatttc aaactttaca 2250

 ttgaaacata atttccttgg aaaacaaacc ataagcctga ggaggttttt 2300

 atcaactgga atgctttata ttagtttgtt tttcactgta cattcctcat 2350

 tttacattca tttaacctgc cgattattta atttttttat tgtaaagtag 2400

 tttttagcat ttgcttttat ttttttactt tgatgccttt tcaaattggc 2450

 atgtctttaa agtatttttc ttcctgatta aaaatgtgtg tgtatgtgtg 2500

 tgtgtgtgtg tatatatata tattttttta aatcacatta attttaccaa 2550

 gtgaaaccaa gccatactgt ttttgagcca attaagaaaa ttgccatttt 2600

 taaagtgtag catttcaggg taaagaccca tgaaatggct tgatgtattc 2650

 tagactactg aaagaaaacc acttcaaaga ttttgttgaa agttttagtg 2700

 ttgtctgaaa tgcaagaggg aaggtgattg gtagtgagtt aaaagaaaaa 2750

 gagaggaaaa gagagtagtt ttgtcttcaa gtaaaatgtc tggttgtgcc 2800

 agacatttca caagtgtgaa aggagatagg agaagctcaa cttgagggcg 2850

 tgtagtaagt tgtagaaggc tcgaggggac gtggacttat ttgccttggt 2900

 ttgcaatacc tgcaaataat gagtttgaaa agaaacaatg aaatgtgtta 2950

 aaaatttgac catattagat aaattttggt ggatttagtc ataagatgga 3000

 aaaagactgg tgaatctttt attacaaaat gtttctgtta aaatgggatc 3050

 atcatctttg aaagggggga ggaggagtaa aagcccgatt ataatggtga 3100

 tcaattcaag tcagtgttga ctattctgtg aaatatattt ggccagtgga 3150

 aatgataatc agaaaagact gtaaatagat ccatccaaat gatttctctg 3200

 tacaaatgaa tgatactatt aaaaaaaaaa aaaaaa 3236

<210> 458
<211> 542
<212> PRT
<213> Homo sapien

<400> 458
 Met Val Ala His Asp Glu Thr Gly Gly Leu Leu Pro Ile Lys Arg
   1               5                  10                  15

 Thr Ile Arg Val Leu Asp Val Asn Asn Gln Ser Phe Arg Glu Gln
                  20                  25                  30

 Glu Glu Pro Ser Asn Lys Arg Val Arg Pro Leu Ala Arg Val Thr
                  35                  40                  45

 Ser Leu Ala Asn Leu Ile Ser Pro Val Arg Asn Gly Ala Val Arg
                  50                  55                  60

 Arg Phe Gly Gln Thr Ile Gln Ser Phe Thr Leu Arg Gly Asp His
                  65                  70                  75

 Arg Ser Pro Ala Ser Ala Gln Lys Phe Ser Ser Arg Ser Thr Val
                  80                  85                  90

 Pro Thr Pro Ala Lys Arg Arg Ser Ser Ala Leu Trp Ser Glu Met
                  95                 100                 105

 Leu Asp Ile Thr Met Lys Glu Ser Leu Thr Thr Arg Glu Ile Arg
                 110                 115                 120

 Arg Gln Glu Ala Ile Tyr Glu Met Ser Arg Gly Glu Gln Asp Leu
                 125                 130                 135

 Ile Glu Asp Leu Lys Leu Ala Arg Lys Ala Tyr His Asp Pro Met
                 140                 145                 150

 Leu Lys Leu Ser Ile Met Ser Glu Glu Glu Leu Thr His Ile Phe
                 155                 160                 165

 Gly Asp Leu Asp Ser Tyr Ile Pro Leu His Glu Asp Leu Leu Thr
                 170                 175                 180

 Arg Ile Gly Glu Ala Thr Lys Pro Asp Gly Thr Val Glu Gln Ile
                 185                 190                 195

 Gly His Ile Leu Val Ser Trp Leu Pro Arg Leu Asn Ala Tyr Arg
                 200                 205                 210

 Gly Tyr Cys Ser Asn Gln Leu Ala Ala Lys Ala Leu Leu Asp Gln
                 215                 220                 225

 Lys Lys Gln Asp Pro Arg Val Gln Asp Phe Leu Gln Arg Cys Leu
                 230                 235                 240

 Glu Ser Pro Phe Ser Arg Lys Leu Asp Leu Trp Ser Phe Leu Asp
                 245                 250                 255

 Ile Pro Arg Ser Arg Leu Val Lys Tyr Pro Leu Leu Leu Lys Glu
                 260                 265                 270

 Ile Leu Lys His Thr Pro Lys Glu His Pro Asp Val Gln Leu Leu
                 275                 280                 285

 Glu Asp Ala Ile Leu Ile Ile Gln Gly Val Leu Ser Asp Ile Asn
                 290                 295                 300

 Leu Lys Lys Gly Glu Ser Glu Cys Gln Tyr Tyr Ile Asp Lys Leu
                 305                 310                 315

 Glu Tyr Leu Asp Glu Lys Gln Arg Asp Pro Arg Ile Glu Ala Ser
                 320                 325                 330

 Lys Val Leu Leu Cys His Gly Glu Leu Arg Ser Lys Ser Gly His
                 335                 340                 345

 Lys Leu Tyr Ile Phe Leu Phe Gln Asp Ile Leu Val Leu Thr Arg
                 350                 355                 360

 Pro Val Thr Arg Asn Glu Arg His Ser Tyr Gln Val Tyr Arg Gln
                 365                 370                 375

 Pro Ile Pro Val Gln Glu Leu Val Leu Glu Asp Leu Gln Asp Gly
                 380                 385                 390

 Asp Val Arg Met Gly Gly Ser Phe Arg Gly Ala Phe Ser Asn Ser
                 395                 400                 405

 Glu Lys Ala Lys Asn Ile Phe Arg Ile Arg Phe His Asp Pro Ser
                 410                 415                 420

 Pro Ala Gln Ser His Thr Leu Gln Ala Asn Asp Val Phe His Lys
                 425                 430                 435

 Gln Gln Trp Phe Asn Cys Ile Arg Ala Ala Ile Ala Pro Phe Gln
                 440                 445                 450

 Ser Ala Gly Ser Pro Pro Glu Leu Gln Gly Leu Pro Glu Leu His
                 455                 460                 465

 Glu Glu Cys Glu Gly Asn His Pro Ser Ala Arg Lys Leu Thr Ala
                 470                 475                 480

 Gln Arg Arg Ala Ser Thr Val Ser Ser Val Thr Gln Val Glu Val
                 485                 490                 495

 Asp Glu Asn Ala Tyr Arg Cys Gly Ser Gly Met Gln Met Ala Glu
                 500                 505                 510

 Asp Ser Lys Ser Leu Lys Thr His Gln Thr Gln Pro Gly Ile Arg
                 515                 520                 525

 Arg Ala Arg Asp Lys Ala Leu Ser Gly Gly Lys Arg Lys Glu Thr
                 530                 535                 540

 Leu Val


<210> 459
<211> 865
<212> DNA
<213> Homo sapien

<400> 459
 ctcaaacacc gcctgctaaa aatacccgac tggaggagca taaaagcgca 50

 gccgagccca gcgccccgca cttttctgag cagacgtcca gagcagagtc 100

 agccagcatg accgagcgcc gcgtcccctt ctcgctcctg cggggcccca 150

 gctgggaccc cttccgcgac tggtacccgc atagccgcct cttcgaccag 200

 gccttcgggc tgccccggct gccggaggag tggtcgcagt ggttaggcgg 250

 cagcagctgg ccaggctacg tgcgccccct gccccccgcc gccatcgaga 300

 gccccgcagt ggccgcgccc gcctacagcc gcgcgctcag ccggcaactc 350

 agcagcgggg tctcggagat ccggcacact gcggaccgct ggcgcgtgtc 400

 cctggatgtc aaccacttcg ccccggacga gctgacggtc aagaccaagg 450

 atggcgtggt ggagatcacc ggcaagcacg aggagcggca ggacgagcat 500

 ggctacatct cccggtgctt cacgcggaaa tacacgctgc cccccggtgt 550

 ggaccccacc caagtttcct cctccctgtc ccctgagggc acactgaccg 600

 tggaggcccc catgcccaag ctagccacgc agtccaacga gatcaccatc 650

 ccagtcacct tcgagtcgcg ggcccagctt gggggcccag aagctgcaaa 700

 atccgatgag actgccgcca agtaaagcct tagcctggat gcccacccct 750

 gctgccgcca ctggctgtgc ctcccccgcc acctgtgtgt tcttttgata 800

 catttatctt ctgtttttct caaataaagt tcaaagcaac cacctgtaaa 850

 aaaaaaaaaa aaaaa 865

<210> 460
<211> 205
<212> PRT
<213> Homo sapien

<400> 460
 Met Thr Glu Arg Arg Val Pro Phe Ser Leu Leu Arg Gly Pro Ser
   1               5                  10                  15

 Trp Asp Pro Phe Arg Asp Trp Tyr Pro His Ser Arg Leu Phe Asp
                  20                  25                  30

 Gln Ala Phe Gly Leu Pro Arg Leu Pro Glu Glu Trp Ser Gln Trp
                  35                  40                  45

 Leu Gly Gly Ser Ser Trp Pro Gly Tyr Val Arg Pro Leu Pro Pro
                  50                  55                  60

 Ala Ala Ile Glu Ser Pro Ala Val Ala Ala Pro Ala Tyr Ser Arg
                  65                  70                  75

 Ala Leu Ser Arg Gln Leu Ser Ser Gly Val Ser Glu Ile Arg His
                  80                  85                  90

 Thr Ala Asp Arg Trp Arg Val Ser Leu Asp Val Asn His Phe Ala
                  95                 100                 105

 Pro Asp Glu Leu Thr Val Lys Thr Lys Asp Gly Val Val Glu Ile
                 110                 115                 120

 Thr Gly Lys His Glu Glu Arg Gln Asp Glu His Gly Tyr Ile Ser
                 125                 130                 135

 Arg Cys Phe Thr Arg Lys Tyr Thr Leu Pro Pro Gly Val Asp Pro
                 140                 145                 150

 Thr Gln Val Ser Ser Ser Leu Ser Pro Glu Gly Thr Leu Thr Val
                 155                 160                 165

 Glu Ala Pro Met Pro Lys Leu Ala Thr Gln Ser Asn Glu Ile Thr
                 170                 175                 180

 Ile Pro Val Thr Phe Glu Ser Arg Ala Gln Leu Gly Gly Pro Glu
                 185                 190                 195

 Ala Ala Lys Ser Asp Glu Thr Ala Ala Lys
                 200                 205

<210> 461
<211> 2493
<212> DNA
<213> Homo sapien

<400> 461
 actgcgactc gagacagcgg cccggcagga cagctccaga atgaaaatgc 50

 ggttcttggg gttggtggtc tgtttggttc tctggcccct gcattctgag 100

 gggtctggag ggaaactgac agctgtggat cctgaaacaa acatgaatgt 150

 gagtgaaatt atctcttact ggggattccc tagtgaggaa tacctagttg 200

 agacagaaga tggatatatt ctgtgcctta accgaattcc tcatgggagg 250

 aagaaccatt ctgacaaagg tcccaaacca gttgtcttcc tgcaacatgg 300

 cttgctggca gattctagta actgggtcac aaaccttgcc aacagcagcc 350

 tgggcttcat tcttgctgat gctggttttg acgtgtggat gggcaacagc 400

 agaggaaata cctggtctcg gaaacataag acactctcag tttctcagga 450

 tgaattctgg gctttcagtt atgatgagat ggcaaaatat gacctaccag 500

 cttccattaa cttcattctg aataaaactg gccaagaaca agtgtattat 550

 gtgggtcatt ctcaaggcac cactataggt tttatagcat tttcacagat 600

 ccctgagctg gctaaaagga ttaaaatgtt ttttgccctg ggtcctgtgg 650

 cttccgtcgc cttctgtact agccctatgg ccaaattagg acgattacca 700

 gatcatctca ttaaggactt atttggagac aaagaatttc ttccccagag 750

 tgcgtttttg aagtggctgg gtacccacgt ttgcactcat gtcatactga 800

 aggagctctg tggaaatctc tgttttcttc tgtgtggatt taatgagaga 850

 aatttaaata tgtctagagt ggatgtatat acaacacatt ctcctgctgg 900

 aacttctgtg caaaacatgt tacactggag ccaggctgtt aaattccaaa 950

 agtttcaagc ctttgactgg ggaagcagtg ccaagaatta ttttcattac 1000

 aaccagagtt atcctcccac atacaatgtg aaggacatgc ttgtgccgac 1050

 tgcagtctgg agcgggggtc acgactggct tgcagatgtc tacgacgtca 1100

 atatcttact gactcagatc accaacttgg tgttccatga gagcattccg 1150

 gaatgggagc atcttgactt catttggggc ctggatgccc cttggaggct 1200

 ttataataaa attattaatc taatgaggaa atatcagtga aagctggact 1250

 tgagctgtgt accaccaagt caatgattat gtcatgtgaa aatgtgtttg 1300

 cttcatttct gtaaaacact tgtttttctt tcccaggtct tttgtttttt 1350

 tatatccaag aaaatgataa ctttgaagat gcccagttca ctctagtttc 1400

 aattagaaac atactagcta ttttttcttt aattagggct ggaataggaa 1450

 gccagtgtct caaccatagt attgtctctt taagtctttt aaatatcact 1500

 gatgtgtaaa aaggtcatta tatccattct gtttttaaaa tttaaaatat 1550

 attgactttt tgcccttcat aggacaaagt aatatatgtg ttggaatttt 1600

 aaaattgtgt tgtcattggt aaatctgtca ctgacttaag cgaggtataa 1650

 aagtacgcag ttttcatgtc cttgccttaa agagctctct agtctaacgg 1700

 tcttgtagtt agagatctaa atgacatttt atcatgtttt cctgcagcag 1750

 gtgcatagtc aaatccagaa atatcacagc tgtgccagta ataaggatgc 1800

 taacaattaa ttttatcaaa cctaactgtg acagctgtga tttgacacgt 1850

 tttaattgct caggttaaat gaaatagttt tccggcgtct tcaaaaacaa 1900

 attgcactga taaaacaaaa acaaaagtat gttttaaatg ctttgaagac 1950

 tgatacactc aaccatctat attcatgagc tctcaatttc atggcaggcc 2000

 atagttctac ttatctgaga agcaaatccc tgtggagact ataccactat 2050

 tttttctgag attaatgtac tcttggagcc cgctactgtc gttattgatc 2100

 acatctgtgt gaagccaaag ccccgtggtt gcccatgaga agtgtccttg 2150

 ttcattttca cccaaatgaa gtgtgaacgt gatgttttcg gatgcaaact 2200

 cagctcaggg attcattttg tgtcttagtt ttatatgcat ccttattttt 2250

 aatacacctg cttcacgtcc ctatgttggg aagtccatat ttgtctgctt 2300

 ttcttgcagc atcatttcct tacaatactg tccggtggac aaaatgacaa 2350

 ttgatatgtt tttctgatat aattacttta gctgcactaa cagtacaatg 2400

 cttgttaatg gttaatatag gcagggcgaa tactactttg taacttttaa 2450

 agtcttaaac ttttcaataa aattgagtga gacttatagg ccc 2493

<210> 462
<211> 399
<212> PRT
<213> Homo sapien

<400> 462
 Met Lys Met Arg Phe Leu Gly Leu Val Val Cys Leu Val Leu Trp
   1               5                  10                  15

 Pro Leu His Ser Glu Gly Ser Gly Gly Lys Leu Thr Ala Val Asp
                  20                  25                  30

 Pro Glu Thr Asn Met Asn Val Ser Glu Ile Ile Ser Tyr Trp Gly
                  35                  40                  45

 Phe Pro Ser Glu Glu Tyr Leu Val Glu Thr Glu Asp Gly Tyr Ile
                  50                  55                  60

 Leu Cys Leu Asn Arg Ile Pro His Gly Arg Lys Asn His Ser Asp
                  65                  70                  75

 Lys Gly Pro Lys Pro Val Val Phe Leu Gln His Gly Leu Leu Ala
                  80                  85                  90

 Asp Ser Ser Asn Trp Val Thr Asn Leu Ala Asn Ser Ser Leu Gly
                  95                 100                 105

 Phe Ile Leu Ala Asp Ala Gly Phe Asp Val Trp Met Gly Asn Ser
                 110                 115                 120

 Arg Gly Asn Thr Trp Ser Arg Lys His Lys Thr Leu Ser Val Ser
                 125                 130                 135

 Gln Asp Glu Phe Trp Ala Phe Ser Tyr Asp Glu Met Ala Lys Tyr
                 140                 145                 150

 Asp Leu Pro Ala Ser Ile Asn Phe Ile Leu Asn Lys Thr Gly Gln
                 155                 160                 165

 Glu Gln Val Tyr Tyr Val Gly His Ser Gln Gly Thr Thr Ile Gly
                 170                 175                 180

 Phe Ile Ala Phe Ser Gln Ile Pro Glu Leu Ala Lys Arg Ile Lys
                 185                 190                 195

 Met Phe Phe Ala Leu Gly Pro Val Ala Ser Val Ala Phe Cys Thr
                 200                 205                 210

 Ser Pro Met Ala Lys Leu Gly Arg Leu Pro Asp His Leu Ile Lys
                 215                 220                 225

 Asp Leu Phe Gly Asp Lys Glu Phe Leu Pro Gln Ser Ala Phe Leu
                 230                 235                 240

 Lys Trp Leu Gly Thr His Val Cys Thr His Val Ile Leu Lys Glu
                 245                 250                 255

 Leu Cys Gly Asn Leu Cys Phe Leu Leu Cys Gly Phe Asn Glu Arg
                 260                 265                 270

 Asn Leu Asn Met Ser Arg Val Asp Val Tyr Thr Thr His Ser Pro
                 275                 280                 285

 Ala Gly Thr Ser Val Gln Asn Met Leu His Trp Ser Gln Ala Val
                 290                 295                 300

 Lys Phe Gln Lys Phe Gln Ala Phe Asp Trp Gly Ser Ser Ala Lys
                 305                 310                 315

 Asn Tyr Phe His Tyr Asn Gln Ser Tyr Pro Pro Thr Tyr Asn Val
                 320                 325                 330

 Lys Asp Met Leu Val Pro Thr Ala Val Trp Ser Gly Gly His Asp
                 335                 340                 345

 Trp Leu Ala Asp Val Tyr Asp Val Asn Ile Leu Leu Thr Gln Ile
                 350                 355                 360

 Thr Asn Leu Val Phe His Glu Ser Ile Pro Glu Trp Glu His Leu
                 365                 370                 375

 Asp Phe Ile Trp Gly Leu Asp Ala Pro Trp Arg Leu Tyr Asn Lys
                 380                 385                 390

 Ile Ile Asn Leu Met Arg Lys Tyr Gln
                 395

<210> 463
<211> 1535
<212> DNA
<213> Homo sapien

<400> 463
 cctccgctca gtccgggagc gcacgtgggc cgcggcgctc cgacctccgc 50

 tttcccaccg cccgcagctg aagcacatcc cgcagcccgg cgcggactcc 100

 gatcgccgca gttgccctct ggcgccatgt cgcagaacgg agcgcccggg 150

 atgcaggagg agagcctgca gggctcctgg gtagaactgc acttcagcaa 200

 taatgggaac gggggcagcg ttccagcctc ggtttctatt tataatggag 250

 acatggaaaa aatactgctg gacgcacagc atgagtctgg acggagtagc 300

 tccaagagct ctcactgtga cagcccacct cgctcgcaga caccacaaga 350

 taccaacagg gcttctgaaa cagataccca tagcattgga gagaaaaaca 400

 gctcacagtc tgaggaagat gatattgaaa gaaggaaaga agttgaaagc 450

 atcttgaaga aaaactcaga ttggatatgg gattggtcaa gtcggccgga 500

 aaatattccc cccaaggagt tcctctttaa acacccgaag cgcacggcca 550

 ccctcagcat gaggaacacg agcgtcatga agaaaggggg catattctct 600

 gcagaatttc tgaaagtttt ccttccatct ctgctgctct ctcatttgct 650

 ggccatcgga ttggggatct atattggaag gcgtctgaca acctccacca 700

 gcaccttttg atgaagaact ggagtctgac ttggttcgtt agtggattac 750

 ttctgagctt gcaacatagc tcactgaaga gctgttagat cctggggtgg 800

 ccacgtcact tgtgtttatt tgttctgtaa atgctgcgtt cctaatttag 850

 taaaataaaa gaatagacac taaaatcatg ttgatctata attacaccta 900

 tgggatcaat aagcatgtca gactgattaa tgtctactgt gaaaatttgg 950

 tagtaaattt tcatttgata ttagatataa atatctgaat ataaataatt 1000

 ttaatatact agtcatgatg tgtgttgtat tttaaaaatt atctgcaacc 1050

 ttaattcagc tgaagtactt tatatttcaa aagaatgaat aacattgata 1100

 ataaaatcgc tactttaagg ggtttgtcca aaataaatat tgtggcctta 1150

 tatatcacac tattgtagaa agtattattt aatttaaatg gatgcaggtt 1200

 gtctactaaa gaaagattat atataactat gctaattgtt cataatcaac 1250

 agaaaccaag atagagctac aaactcagct gtacagttcg tacactaaac 1300

 tcttcttgct tttgcattat aaggaattaa gtctccgatt attaggtgat 1350

 caccctggat gatcagtttt ctgctgaagg cacctactca gtatcttttc 1400

 ctctttatca ctctgcattg gtgaatttaa tcctctcctt tgtgttcaac 1450

 ttttgtgtgc ttttaaaatc agctttattc taagcaaatc tgtgtctact 1500

 ttaaaaaact ggaaatggaa aaaaaaataa atctt 1535

<210> 464
<211> 194
<212> PRT
<213> Homo sapien

<400> 464
 Met Ser Gln Asn Gly Ala Pro Gly Met Gln Glu Glu Ser Leu Gln
   1               5                  10                  15

 Gly Ser Trp Val Glu Leu His Phe Ser Asn Asn Gly Asn Gly Gly
                  20                  25                  30

 Ser Val Pro Ala Ser Val Ser Ile Tyr Asn Gly Asp Met Glu Lys
                  35                  40                  45

 Ile Leu Leu Asp Ala Gln His Glu Ser Gly Arg Ser Ser Ser Lys
                  50                  55                  60

 Ser Ser His Cys Asp Ser Pro Pro Arg Ser Gln Thr Pro Gln Asp
                  65                  70                  75

 Thr Asn Arg Ala Ser Glu Thr Asp Thr His Ser Ile Gly Glu Lys
                  80                  85                  90

 Asn Ser Ser Gln Ser Glu Glu Asp Asp Ile Glu Arg Arg Lys Glu
                  95                 100                 105

 Val Glu Ser Ile Leu Lys Lys Asn Ser Asp Trp Ile Trp Asp Trp
                 110                 115                 120

 Ser Ser Arg Pro Glu Asn Ile Pro Pro Lys Glu Phe Leu Phe Lys
                 125                 130                 135

 His Pro Lys Arg Thr Ala Thr Leu Ser Met Arg Asn Thr Ser Val
                 140                 145                 150

 Met Lys Lys Gly Gly Ile Phe Ser Ala Glu Phe Leu Lys Val Phe
                 155                 160                 165

 Leu Pro Ser Leu Leu Leu Ser His Leu Leu Ala Ile Gly Leu Gly
                 170                 175                 180

 Ile Tyr Ile Gly Arg Arg Leu Thr Thr Ser Thr Ser Thr Phe
                 185                 190

<210> 465
<211> 1221
<212> DNA
<213> Homo sapien

<400> 465
 cgcaggctgg aaggaagacg aacctacgaa gcagagatct gaagacagca 50

 tgtacacagc cattccccag agtggctctc cattcccagg ctcagtgcag 100

 gatccaggcc tgcatgtgtg gcgggtggag aagctgaagc cggtgcctgt 150

 ggcgcaagag aaccagggcg tcttcttctc gggggactcc tacctagtgc 200

 tgcacaatgg cccagaagag gtttcccatc tgcacctgtg gataggccag 250

 cagtcatccc gggatgagca gggggcctgt gccgtgctgg ctgtgcacct 300

 caacacgctg ctgggagagc ggcctgtgca gcaccgcgag gtgcagggca 350

 atgagtctga cctcttcatg agctacttcc cacggggcct caagtaccag 400

 gaaggtggtg tggagtcagc atttcacaag acctccacag gagccccagc 450

 tgccatcaag aaactctacc aggtgaaggg gaagaagaac atccgtgcca 500

 ccgagcgggc actgaactgg gacagcttca acactgggga ctgcttcatc 550

 ctggacctgg gccagaacat cttcgcctgg tgtggtggaa agtccaacat 600

 cctggaacgc aacaaggcga gggacctggc cctggccatc cgggacagtg 650

 agcgacaggg caaggcccag gtggagattg tcactgatgg ggaggagcct 700

 gctgagatga tccaggtcct gggccccaag cctgctctga aggagggcaa 750

 ccctgaggaa gacctcacag ctgacaaggc aaatgcccag gccgcagctc 800

 tgtataaggt ctctgatgcc actggacaga tgaacctgac caaggtggct 850

 gactccagcc cctttgccct tgaactgctg atatctgatg actgctttgt 900

 gctggacaac gggctctgtg gcaagatcta tatctggaag gggcgaaaag 950

 cgaatgagaa ggagcggcag gcagccctgc aggtggccga gggcttcatc 1000

 tcgcgcatgc agtacgcccc gaacactcag gtggagattc tgcctcaggg 1050

 ccgtgagagt cccatcttca agcaattttt caaggactgg aaatgagggt 1100

 gggcgtcttc ctgccccatg ctcccctgcc ccccaccacc tgcctgcttg 1150

 cttctctggc tgcctggtca gtgcagaggt gccccctgca gatgttcaat 1200

 aaaggagaca agtgctttcc c 1221

<210> 466
<211> 348
<212> PRT
<213> Homo sapien

<400> 466
 Met Tyr Thr Ala Ile Pro Gln Ser Gly Ser Pro Phe Pro Gly Ser
   1               5                  10                  15

 Val Gln Asp Pro Gly Leu His Val Trp Arg Val Glu Lys Leu Lys
                  20                  25                  30

 Pro Val Pro Val Ala Gln Glu Asn Gln Gly Val Phe Phe Ser Gly
                  35                  40                  45

 Asp Ser Tyr Leu Val Leu His Asn Gly Pro Glu Glu Val Ser His
                  50                  55                  60

 Leu His Leu Trp Ile Gly Gln Gln Ser Ser Arg Asp Glu Gln Gly
                  65                  70                  75

 Ala Cys Ala Val Leu Ala Val His Leu Asn Thr Leu Leu Gly Glu
                  80                  85                  90

 Arg Pro Val Gln His Arg Glu Val Gln Gly Asn Glu Ser Asp Leu
                  95                 100                 105

 Phe Met Ser Tyr Phe Pro Arg Gly Leu Lys Tyr Gln Glu Gly Gly
                 110                 115                 120

 Val Glu Ser Ala Phe His Lys Thr Ser Thr Gly Ala Pro Ala Ala
                 125                 130                 135

 Ile Lys Lys Leu Tyr Gln Val Lys Gly Lys Lys Asn Ile Arg Ala
                 140                 145                 150

 Thr Glu Arg Ala Leu Asn Trp Asp Ser Phe Asn Thr Gly Asp Cys
                 155                 160                 165

 Phe Ile Leu Asp Leu Gly Gln Asn Ile Phe Ala Trp Cys Gly Gly
                 170                 175                 180

 Lys Ser Asn Ile Leu Glu Arg Asn Lys Ala Arg Asp Leu Ala Leu
                 185                 190                 195

 Ala Ile Arg Asp Ser Glu Arg Gln Gly Lys Ala Gln Val Glu Ile
                 200                 205                 210

 Val Thr Asp Gly Glu Glu Pro Ala Glu Met Ile Gln Val Leu Gly
                 215                 220                 225

 Pro Lys Pro Ala Leu Lys Glu Gly Asn Pro Glu Glu Asp Leu Thr
                 230                 235                 240

 Ala Asp Lys Ala Asn Ala Gln Ala Ala Ala Leu Tyr Lys Val Ser
                 245                 250                 255

 Asp Ala Thr Gly Gln Met Asn Leu Thr Lys Val Ala Asp Ser Ser
                 260                 265                 270

 Pro Phe Ala Leu Glu Leu Leu Ile Ser Asp Asp Cys Phe Val Leu
                 275                 280                 285

 Asp Asn Gly Leu Cys Gly Lys Ile Tyr Ile Trp Lys Gly Arg Lys
                 290                 295                 300

 Ala Asn Glu Lys Glu Arg Gln Ala Ala Leu Gln Val Ala Glu Gly
                 305                 310                 315

 Phe Ile Ser Arg Met Gln Tyr Ala Pro Asn Thr Gln Val Glu Ile
                 320                 325                 330

 Leu Pro Gln Gly Arg Glu Ser Pro Ile Phe Lys Gln Phe Phe Lys
                 335                 340                 345

 Asp Trp Lys


<210> 467
<211> 3195
<212> DNA
<213> Homo sapien

<400> 467
 agaggcttcc ctggctggtg cctgagcccg gcgtccctcg ccccccgccc 50

 tccccgcatc cctctcctcc ctcgcgcctg gccctgtggc tcttcctccc 100

 tccctccttc cccccccccc cacccctcgc ccgctgcctc cctcggccca 150

 gccagctgtg ccggcgtttg ttggctgccc tgcgcccggc cctccagcca 200

 gccttctgcc ggccccgccg cgatggaggt gccccagccg gagcccgcgc 250

 caggctcggc tctcagtcca gcaggcgtgt gcggtggcgc ccagcgtccg 300

 ggccacctcc cgggcctcct gctgggatct catggcctcc tggggtcccc 350

 ggtgcgggcg gccgcttcct cgccggtcac caccctcacc cagaccatgc 400

 acgacctcgc cgggctcggc agccgcagcc gcctgacgca cctatccctg 450

 tctcgacggg catccgaatc ctccctgtcg tctgaatcct ccgaatcttc 500

 tgatgcaggt ctctgcatgg attcccccag ccctatggac ccccacatgg 550

 cggagcagac gtttgaacag gccatccagg cagccagccg gatcattcga 600

 aacgagcagt ttgccatcag acgcttccag tctatgccgg tgaggctgct 650

 gggccacagc cccgtgcttc ggaacatcac caactcccag gcgcccgacg 700

 gccggaggaa gagcgaggcg ggcagtggag ctgccagcag ctctggggaa 750

 gacaaggaga atgtgcgctt ctggaaggcc ggggtgggag ctctccggga 800

 agaggagggg gcatgctggg gtggttccct ggcatgtgag gaccctcctc 850

 tcccatcttg gctgcaggat ggatttgtct tcaagatgcc atggaagccc 900

 acacatccca gctccaccca tgctctggca gagtgggcca gccgcaggga 950

 agcctttgcc cagagaccca gctcggcccc cgacctgatg tgtctcagtc 1000

 ctgaccggaa gatggaagtg gaggagctca gccccctggc cctaggtcgc 1050

 ttctctctga cccctgcaga gggggatact gaggaagatg atggatttgt 1100

 ggacatccta gagagtgact taaaggatga tgatgcagtt cccccaggca 1150

 tggagagtct cattagtgcc ccactggtca agaccttgga aaaggaagag 1200

 gaaaaggacc tcgtcatgta cagcaagtgc cagcggctct tccgctctcc 1250

 gtccatgccc tgcagcgtga tccggcccat cctcaagagg ctggagcggc 1300

 cccaggacag ggacacgccc gtgcagaata agcggaggcg gagcgtgacc 1350

 cctcctgagg agcagcagga ggctgaggaa cctaaagccc gcgtcctccg 1400

 ctcaaaatca ctgtgtcacg atgagatcga gaacctcctg gacagtgacc 1450

 accgagagct gattggagat tactctaagg ccttcctcct acagacagta 1500

 gacggaaagc accaagacct caagtacatc tcaccagaaa cgatggtggc 1550

 cctattgacg ggcaagttca gcaacatcgt ggataagttt gtgattgtag 1600

 actgcagata cccctatgaa tatgaaggcg ggcacatcaa gactgcggtg 1650

 aacttgcccc tggaacgcga cgccgagagc ttcctactga agagccccat 1700

 cgcgccctgt agcctggaca agagagtcat cctcattttc cactgtgaat 1750

 tctcatctga gcgtgggccc cgcatgtgcc gtttcatcag ggaacgagac 1800

 cgtgctgtca acgactaccc cagcctctac taccctgaga tgtatatcct 1850

 gaaaggcggc tacaaggagt tcttccctca gcacccgaac ttctgtgaac 1900

 cccaggacta ccggcccatg aaccacgagg ccttcaagga tgagctaaag 1950

 accttccgcc tcaagactcg cagctgggct ggggagcgga gccggcggga 2000

 gctctgtagc cggctgcagg accagtgagg ggcctgcgcc agtcctgcta 2050

 cctcccttgc ctttcgaggc ctgaagccag ctgccctatg ggcctgccgg 2100

 gctgagggcc tgctggaggc ctcaggtgct gtccatggga aagatggtgt 2150

 ggtgtcctgc ctgtctgccc cagcccagat tcccctgtgt catcccatca 2200

 ttttccatat cctggtgccc cccacccctg gaagagccca gtctgttgag 2250

 ttagttaagt tgggttaata ccagcttaaa ggcagtattt tgtgtcctcc 2300

 aggagcttct tgtttccttg ttagggttaa cccttcatct tcctgtgtcc 2350

 tgaaacgctc ctttgtgtgt gtgtcagctg aggctgggga gagccgtggt 2400

 ccctgaggat gggtcagagc taaactcctt cctggcctga gagtcagctc 2450

 tctgccctgt gtacttcccg ggccagggct gcccctaatc tctgtaggaa 2500

 ccgtggtatg tctgccatgt tgcccctttc tcttttcccc tttcctgtcc 2550

 caccatacga gcacctccag cctgaacaga agctcttact ctttcctatt 2600

 tcagtgttac ctgtgtgctt ggtctgtttg actttacgcc catctcagga 2650

 cacttccgta gactgtttag gttcccctgt caaatatcag ttacccactc 2700

 ggtcccagtt ttgttgcccc agaaagggat gttattatcc ttgggggctc 2750

 ccagggcaag ggttaaggcc tgaatcatga gcctgctgga agcccagccc 2800

 ctactgctgt gaaccctggg gcctgactgc tcagaacttg ctgctgtctt 2850

 gttgcggatg gatggaaggt tggatggatg ggtggatggc cgtggatggc 2900

 cgtggatgcg cagtgccttg catacccaaa ccaggtggga gcgttttgtt 2950

 gagcatgaca cctgcagcag gaatatatgt gtgcctattt gtgtggacaa 3000

 aaatatttac acttagggtt tggagctatt caagaggaaa tgtcacagaa 3050

 gcagctaaac caaggactga gcaccctctg gattctgaat ctcaagatgg 3100

 gggcagggct gtgcttgaag gccctgctga gtcatctgtt agggccttgg 3150

 ttcaataaag cactgagcaa gttgagaaaa aaaaaaaaaa aaaaa 3195

<210> 468
<211> 601
<212> PRT
<213> Homo sapien

<400> 468
 Met Glu Val Pro Gln Pro Glu Pro Ala Pro Gly Ser Ala Leu Ser
   1               5                  10                  15

 Pro Ala Gly Val Cys Gly Gly Ala Gln Arg Pro Gly His Leu Pro
                  20                  25                  30

 Gly Leu Leu Leu Gly Ser His Gly Leu Leu Gly Ser Pro Val Arg
                  35                  40                  45

 Ala Ala Ala Ser Ser Pro Val Thr Thr Leu Thr Gln Thr Met His
                  50                  55                  60

 Asp Leu Ala Gly Leu Gly Ser Arg Ser Arg Leu Thr His Leu Ser
                  65                  70                  75

 Leu Ser Arg Arg Ala Ser Glu Ser Ser Leu Ser Ser Glu Ser Ser
                  80                  85                  90

 Glu Ser Ser Asp Ala Gly Leu Cys Met Asp Ser Pro Ser Pro Met
                  95                 100                 105

 Asp Pro His Met Ala Glu Gln Thr Phe Glu Gln Ala Ile Gln Ala
                 110                 115                 120

 Ala Ser Arg Ile Ile Arg Asn Glu Gln Phe Ala Ile Arg Arg Phe
                 125                 130                 135

 Gln Ser Met Pro Val Arg Leu Leu Gly His Ser Pro Val Leu Arg
                 140                 145                 150

 Asn Ile Thr Asn Ser Gln Ala Pro Asp Gly Arg Arg Lys Ser Glu
                 155                 160                 165

 Ala Gly Ser Gly Ala Ala Ser Ser Ser Gly Glu Asp Lys Glu Asn
                 170                 175                 180

 Val Arg Phe Trp Lys Ala Gly Val Gly Ala Leu Arg Glu Glu Glu
                 185                 190                 195

 Gly Ala Cys Trp Gly Gly Ser Leu Ala Cys Glu Asp Pro Pro Leu
                 200                 205                 210

 Pro Ser Trp Leu Gln Asp Gly Phe Val Phe Lys Met Pro Trp Lys
                 215                 220                 225

 Pro Thr His Pro Ser Ser Thr His Ala Leu Ala Glu Trp Ala Ser
                 230                 235                 240

 Arg Arg Glu Ala Phe Ala Gln Arg Pro Ser Ser Ala Pro Asp Leu
                 245                 250                 255

 Met Cys Leu Ser Pro Asp Arg Lys Met Glu Val Glu Glu Leu Ser
                 260                 265                 270

 Pro Leu Ala Leu Gly Arg Phe Ser Leu Thr Pro Ala Glu Gly Asp
                 275                 280                 285

 Thr Glu Glu Asp Asp Gly Phe Val Asp Ile Leu Glu Ser Asp Leu
                 290                 295                 300

 Lys Asp Asp Asp Ala Val Pro Pro Gly Met Glu Ser Leu Ile Ser
                 305                 310                 315

 Ala Pro Leu Val Lys Thr Leu Glu Lys Glu Glu Glu Lys Asp Leu
                 320                 325                 330

 Val Met Tyr Ser Lys Cys Gln Arg Leu Phe Arg Ser Pro Ser Met
                 335                 340                 345

 Pro Cys Ser Val Ile Arg Pro Ile Leu Lys Arg Leu Glu Arg Pro
                 350                 355                 360

 Gln Asp Arg Asp Thr Pro Val Gln Asn Lys Arg Arg Arg Ser Val
                 365                 370                 375

 Thr Pro Pro Glu Glu Gln Gln Glu Ala Glu Glu Pro Lys Ala Arg
                 380                 385                 390

 Val Leu Arg Ser Lys Ser Leu Cys His Asp Glu Ile Glu Asn Leu
                 395                 400                 405

 Leu Asp Ser Asp His Arg Glu Leu Ile Gly Asp Tyr Ser Lys Ala
                 410                 415                 420

 Phe Leu Leu Gln Thr Val Asp Gly Lys His Gln Asp Leu Lys Tyr
                 425                 430                 435

 Ile Ser Pro Glu Thr Met Val Ala Leu Leu Thr Gly Lys Phe Ser
                 440                 445                 450

 Asn Ile Val Asp Lys Phe Val Ile Val Asp Cys Arg Tyr Pro Tyr
                 455                 460                 465

 Glu Tyr Glu Gly Gly His Ile Lys Thr Ala Val Asn Leu Pro Leu
                 470                 475                 480

 Glu Arg Asp Ala Glu Ser Phe Leu Leu Lys Ser Pro Ile Ala Pro
                 485                 490                 495

 Cys Ser Leu Asp Lys Arg Val Ile Leu Ile Phe His Cys Glu Phe
                 500                 505                 510

 Ser Ser Glu Arg Gly Pro Arg Met Cys Arg Phe Ile Arg Glu Arg
                 515                 520                 525

 Asp Arg Ala Val Asn Asp Tyr Pro Ser Leu Tyr Tyr Pro Glu Met
                 530                 535                 540

 Tyr Ile Leu Lys Gly Gly Tyr Lys Glu Phe Phe Pro Gln His Pro
                 545                 550                 555

 Asn Phe Cys Glu Pro Gln Asp Tyr Arg Pro Met Asn His Glu Ala
                 560                 565                 570

 Phe Lys Asp Glu Leu Lys Thr Phe Arg Leu Lys Thr Arg Ser Trp
                 575                 580                 585

 Ala Gly Glu Arg Ser Arg Arg Glu Leu Cys Ser Arg Leu Gln Asp
                 590                 595                 600

 Gln


<210> 469
<211> 4788
<212> DNA
<213> Homo sapien

<400> 469
 tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa 50

 gctaagttgt ttatctcggc tgcggcggga actgcggacg gtggcgggcg 100

 agcggctcct ctgccagagt tgatattcac tgatggactc caaagaatca 150

 ttaactcctg gtagagaaga aaaccccagc agtgtgcttg ctcaggagag 200

 gggagatgtg atggacttct ataaaaccct aagaggagga gctactgtga 250

 aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc 300

 aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc 350

 gcagcagcca gatctgtcca aagcagtttc actctcaatg ggactgtata 400

 tgggagagac agaaacaaaa gtgatgggaa atgacctggg attcccacag 450

 cagggccaaa tcagcctttc ctcgggggaa acagacttaa agcttttgga 500

 agaaagcatt gcaaacctca ataggtcgac cagtgttcca gagaacccca 550

 agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt 600

 ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca 650

 gactggcacc aacggtggca atgtgaaatt gtataccaca gaccaaagca 700

 cctttgacat tttgcaggat ttggagtttt cttctgggtc cccaggtaaa 750

 gagacgaatg agagtccttg gagatcagac ctgttgatag atgaaaactg 800

 tttgctttct cctctggcgg gagaagacga ttcattcctt ttggaaggaa 850

 actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa 900

 attaaggata atggagatct ggttttgtca agccccagta atgtaacact 950

 gccccaagtg aaaacagaaa aagaagattt catcgaactc tgcacccctg 1000

 gggtaattaa gcaagagaaa ctgggcacag tttactgtca ggcaagcttt 1050

 cctggagcaa atataattgg taataaaatg tctgccattt ctgttcatgg 1100

 tgtgagtacc tctggaggac agatgtacca ctatgacatg aatacagcat 1150

 ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca 1200

 attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga 1250

 caacttgact tctctgggga ctctgaactt ccctggtcga acagtttttt 1300

 ctaatggcta ttcaagcccc agcatgagac cagatgtaag ctctcctcca 1350

 tccagctcct caacagcaac aacaggacca cctcccaaac tctgcctggt 1400

 gtgctctgat gaagcttcag gatgtcatta tggagtctta acttgtggaa 1450

 gctgtaaagt tttcttcaaa agagcagtgg aaggacagca caattaccta 1500

 tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg 1550

 cccagcatgc cgctatcgaa aatgtcttca ggctggaatg aacctggaag 1600

 ctcgaaaaac aaagaaaaaa ataaaaggaa ttcagcaggc cactacagga 1650

 gtctcacaag aaacctctga aaatcctggt aacaaaacaa tagttcctgc 1700

 aacgttacca caactcaccc ctaccctggt gtcactgttg gaggttattg 1750

 aacctgaagt gttatatgca ggatatgata gctctgttcc agactcaact 1800

 tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc 1850

 agcagtgaaa tgggcaaagg caataccagg tttcaggaac ttacacctgg 1900

 atgaccaaat gaccctactg cagtactcct ggatgtttct tatggcattt 1950

 gctctggggt ggagatcata tagacaatca agtgcaaacc tgctgtgttt 2000

 tgctcctgat ctgattatta atgagcagag aatgactcta ccctgcatgt 2050

 acgaccaatg taaacacatg ctgtatgttt cctctgagtt acacaggctt 2100

 caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc 2150

 ttcagttcct aaggacggtc tgaagagcca agagctattt gatgaaatta 2200

 gaatgaccta catcaaagag ctaggaaaag ccattgtcaa gagggaagga 2250

 aactccagcc agaactggca gcggttttat caactgacaa aactcttgga 2300

 ttctatgcat gaagtggttg aaaatctcct taactattgc ttccaaacat 2350

 ttttggataa gaccatgagt attgaattcc ccgagatgtt agctgaaatc 2400

 atcaccaatc agataccaaa atattcaaat ggaaatatca aaaaacttct 2450

 gtttcatcaa aagtgactgc cttaataaga atggttgcct taaagaaagt 2500

 cgaattaata gcttttattg tataaactat cagtttgtcc tgtagaggtt 2550

 ttgttgtttt attttttatt gttttcatct gttgttttgt tttaaatacg 2600

 cactacatgt ggtttataga gggccaagac ttggcaacag aagcagttga 2650

 gtcgtcatca cttttcagtg atgggagagt agatggtgaa atttattagt 2700

 taatatatcc cagaaattag aaaccttaat atgtggacgt aatctccaca 2750

 gtcaaagaag gatggcacct aaaccaccag tgcccaaagt ctgtgtgatg 2800

 aactttctct tcatactttt tttcacagtt ggctggatga aattttctag 2850

 actttctgtt ggtgtatccc ccccctgtat agttaggata gcatttttga 2900

 tttatgcatg gaaacctgaa aaaaagttta caagtgtata tcagaaaagg 2950

 gaagttgtgc cttttatagc tattactgtc tggttttaac aatttccttt 3000

 atatttagtg aactacgctt gctcattttt tcttacataa ttttttattc 3050

 aagttattgt acagctgttt aagatgggca gctagttcgt agctttccca 3100

 aataaactct aaacattaat caatcatctg tgtgaaaatg ggttggtgct 3150

 tctaacctga tggcacttag ctatcagaag accacaaaaa ttgactcaaa 3200

 tctccagtat tcttgtcaaa aaaaaaaaaa aaaaagctca tattttgtat 3250

 atatctgctt cagtggagaa ttatataggt tgtgcaaatt aacagtccta 3300

 actggtatag agcacctagt ccagtgacct gctgggtaaa ctgtggatga 3350

 tggttgcaaa agactaattt aaaaaataac taccaagagg ccctgtctgt 3400

 acctaacgcc ctatttttgc aatggctata tggcaagaaa gctggtaaac 3450

 tatttgtctt tcaggacctt ttgaagtagt ttgtataact tcttaaaagt 3500

 tgtgattcca gataaccagc tgtaacacag ctgagagact tttaatcaga 3550

 caaagtaatt cctctcacta aactttaccc aaaaactaaa tctctaatat 3600

 ggcaaaaatg gctagacacc cattttcaca ttcccatctg tcaccaattg 3650

 gttaatcttt cctgatggta caggaaagct cagctactga tttttgtgat 3700

 ttagaactgt atgtcagaca tccatgtttg taaaactaca catccctaat 3750

 gtgtgccata gagtttaaca caagtcctgt gaatttcttc actgttgaaa 3800

 attattttaa acaaaataga agctgtagta gccctttctg tgtgcacctt 3850

 accaactttc tgtaaactca aaacttaaca tatttactaa gccacaagaa 3900

 atttgatttc tattcaaggt ggccaaatta tttgtgtaat agaaaactga 3950

 aaatctaata ttaaaaatat ggaacttcta atatattttt atatttagtt 4000

 atagtttcag atatatatca tattggtatt cactaatctg ggaagggaag 4050

 ggctactgca gctttacatg caatttatta aaatgattgt aaaatagctt 4100

 gtatagtgta aaataagaat gatttttaga tgagattgtt ttatcatgac 4150

 atgttatata ttttttgtag gggtcaaaga aatgctgatg gataacctat 4200

 atgatttata gtttgtacat gcattcatac aggcagcgat ggtctcagaa 4250

 accaaacagt ttgctctagg ggaagaggga gatggagact ggtcctgtgt 4300

 gcagtgaagg ttgctgaggc tctgacccag tgagattaca gaggaagtta 4350

 tcctctgcct cccattctga ccacccttct cattccaaca gtgagtctgt 4400

 cagcgcaggt ttagtttact caatctcccc ttgcactaaa gtatgtaaag 4450

 tatgtaaaca ggagacagga aggtggtgct tacatcctta aaggcaccat 4500

 ctaatagcgg gttactttca catacagccc tcccccagca gttgaatgac 4550

 aacagaagct tcagaagttt ggcaatagtt tgcatagagg taccagcaat 4600

 atgtaaatag tgcagaatct cataggttgc caataataca ctaattcctt 4650

 tctatcctac aacaagagtt tatttccaaa taaaatgagg acatgttttt 4700

 gttttctttg aatgcttttt gaatgttatt tgttattttc agtattttgg 4750

 agaaattatt taataaaaaa acaatcattt gctttttg 4788

<210> 470
<211> 777
<212> PRT
<213> Homo sapien

<400> 470
 Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro
   1               5                  10                  15

 Ser Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr
                  20                  25                  30

 Lys Thr Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser
                  35                  40                  45

 Pro Ser Leu Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg
                  50                  55                  60

 Leu Leu Val Asp Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln
                  65                  70                  75

 Pro Asp Leu Ser Lys Ala Val Ser Leu Ser Met Gly Leu Tyr Met
                  80                  85                  90

 Gly Glu Thr Glu Thr Lys Val Met Gly Asn Asp Leu Gly Phe Pro
                  95                 100                 105

 Gln Gln Gly Gln Ile Ser Leu Ser Ser Gly Glu Thr Asp Leu Lys
                 110                 115                 120

 Leu Leu Glu Glu Ser Ile Ala Asn Leu Asn Arg Ser Thr Ser Val
                 125                 130                 135

 Pro Glu Asn Pro Lys Ser Ser Ala Ser Thr Ala Val Ser Ala Ala
                 140                 145                 150

 Pro Thr Glu Lys Glu Phe Pro Lys Thr His Ser Asp Val Ser Ser
                 155                 160                 165

 Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr Asn Gly Gly Asn
                 170                 175                 180

 Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp Ile Leu Gln
                 185                 190                 195

 Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr Asn Glu
                 200                 205                 210

 Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu Leu
                 215                 220                 225

 Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn
                 230                 235                 240

 Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro
                 245                 250                 255

 Lys Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn
                 260                 265                 270

 Val Thr Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu
                 275                 280                 285

 Leu Cys Thr Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val
                 290                 295                 300

 Tyr Cys Gln Ala Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys
                 305                 310                 315

 Met Ser Ala Ile Ser Val His Gly Val Ser Thr Ser Gly Gly Gln
                 320                 325                 330

 Met Tyr His Tyr Asp Met Asn Thr Ala Ser Leu Ser Gln Gln Gln
                 335                 340                 345

 Asp Gln Lys Pro Ile Phe Asn Val Ile Pro Pro Ile Pro Val Gly
                 350                 355                 360

 Ser Glu Asn Trp Asn Arg Cys Gln Gly Ser Gly Asp Asp Asn Leu
                 365                 370                 375

 Thr Ser Leu Gly Thr Leu Asn Phe Pro Gly Arg Thr Val Phe Ser
                 380                 385                 390

 Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro Asp Val Ser Ser Pro
                 395                 400                 405

 Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro Pro Pro Lys Leu
                 410                 415                 420

 Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His Tyr Gly Val
                 425                 430                 435

 Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala Val Glu
                 440                 445                 450

 Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile Ile
                 455                 460                 465

 Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys
                 470                 475                 480

 Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys
                 485                 490                 495

 Lys Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu
                 500                 505                 510

 Thr Ser Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu
                 515                 520                 525

 Pro Gln Leu Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu
                 530                 535                 540

 Pro Glu Val Leu Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser
                 545                 550                 555

 Thr Trp Arg Ile Met Thr Thr Leu Asn Met Leu Gly Gly Arg Gln
                 560                 565                 570

 Val Ile Ala Ala Val Lys Trp Ala Lys Ala Ile Pro Gly Phe Arg
                 575                 580                 585

 Asn Leu His Leu Asp Asp Gln Met Thr Leu Leu Gln Tyr Ser Trp
                 590                 595                 600

 Met Phe Leu Met Ala Phe Ala Leu Gly Trp Arg Ser Tyr Arg Gln
                 605                 610                 615

 Ser Ser Ala Asn Leu Leu Cys Phe Ala Pro Asp Leu Ile Ile Asn
                 620                 625                 630

 Glu Gln Arg Met Thr Leu Pro Cys Met Tyr Asp Gln Cys Lys His
                 635                 640                 645

 Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu Gln Val Ser Tyr
                 650                 655                 660

 Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu Ser Ser Val
                 665                 670                 675

 Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu Ile Arg
                 680                 685                 690

 Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg Glu
                 695                 700                 705

 Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys
                 710                 715                 720

 Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr
                 725                 730                 735

 Cys Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro
                 740                 745                 750

 Glu Met Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser
                 755                 760                 765

 Asn Gly Asn Ile Lys Lys Leu Leu Phe His Gln Lys
                 770                 775

<210> 471
<211> 3568
<212> DNA
<213> Homo sapien

<400> 471
 ccggtcctga gacacgctgt gtggctgaaa agtgaaggca agagctcatt 50

 tggcctctgt gctcccctcc gcaagggatc gtttctccag aagagctgga 100

 tattctttcg cccagttatg gcagacaagt taacgagaat tgctattgtc 150

 aaccatgaca aatgtaaacc taagaaatgt cgacaggaat gcaaaaagag 200

 ttgtcctgta gttcgaatgg gaaaattatg catagaggtt acaccccaga 250

 gcaaaatagc atggatttcc gaaactcttt gtattggttg tggtatctgt 300

 attaagaaat gcccctttgg cgccttatca attgtcaatc taccaagcaa 350

 cttggaaaaa gaaaccacac atcgatattg tgccaatgcc ttcaaacttc 400

 acaggttgcc tatccctcgt ccaggtgaag ttttgggatt agttggaact 450

 aatggtattg gaaagtcagc tgctttaaaa attttagcag gaaaacaaaa 500

 gccaaacctt ggaaagtacg atgatcctcc tgactggcag gagattttga 550

 cttatttccg tggatctgaa ttacaaaatt actttacaaa gattctagaa 600

 gatgacctaa aagccatcat caaacctcaa tatgtagcca gattcctaag 650

 gctggcaaag gggacagtgg gatctatttt ggaccgaaaa gatgaaacaa 700

 agacacaggc aattgtatgt cagcagcttg atttaaccca cctaaaagaa 750

 cgaaatgttg aagatctttc aggaggagag ttgcagagat ttgcttgtgc 800

 tgtcgtttgc atacagaaag ctgatatttt catgtttgat gagccttcta 850

 gttacctaga tgtcaagcag cgtttaaagg ctgctattac tatacgatct 900

 ctaataaatc cagatagata tatcattgtg gtggaacatg atctaagtgt 950

 attagactat ctctccgact tcatctgctg tttatatggt gtaccaagcg 1000

 cctatggagt tgtcactatg ccttttagtg taagagaagg cataaacatt 1050

 tttttggatg gctatgttcc aacagaaaac ttgagattca gagatgcatc 1100

 acttgttttt aaagtggctg agacagcaaa tgaagaagaa gttaaaaaga 1150

 tgtgtatgta taaatatcca ggaatgaaga aaaaaatggg agaatttgag 1200

 ctagcaattg tagctggaga gtttacagat tctgaaatta tggtgatgct 1250

 gggggaaaat ggaacgggta aaacgacatt tatcagaatg cttgctggaa 1300

 gacttaaacc tgatgaagga ggagaagtac cagttctaaa tgtcagttat 1350

 aagccacaga aaattagtcc caaatcaact ggaagtgttc gccagttact 1400

 acatgaaaag ataagagatg cttatactca cccacaattt gtgaccgatg 1450

 taatgaagcc tctgcaaatt gaaaacatca ttgatcaaga ggtgcagaca 1500

 ttatctggtg gtgaactaca gcgagtacgt ttacgccttt gcttgggcaa 1550

 acctgctgat gtctatttaa ttgatgaacc atctgcatat ttggattctg 1600

 agcaaagact gatggcagct cgagttgtca aacgtttcat actccatgca 1650

 aaaaagacag cctttgttgt ggaacatgac ttcatcatgg ccacctatct 1700

 agcggatcgc gtcatcgttt ttgatggtgt tccatctaag aacacagttg 1750

 caaacagtcc tcaaaccctt ttggctggca tgaataaatt tttgtctcag 1800

 cttgaaatta cattcagaag agatccaaac aactataggc cacgaataaa 1850

 caaacttaat tcaattaagg atgtagaaca aaagaagagt ggaaactact 1900

 ttttcttgga tgattagact gactctgaga atattgataa gccatttatt 1950

 aaaaggagta tttactagaa ttttttgtca tataaaactt gaatcaggat 2000

 tttatgcccc acatactctg gaacttgaag tataatatac ttaatataac 2050

 ataaaaagcc agttgggttc taaattgtag ttgaaacaca gaaaatgcca 2100

 cttttctgtt cctgaagagg ctcttttgtg cataatattc taaaatgaag 2150

 acatttcaag ctatacaaat tacttccaag ttttcatgat gtatgggaag 2200

 attttcagta ggtgtattat attcacggta ccaaatgctg accagtgttg 2250

 ctccattttt taaatcttga aaagggtttc tgtacttacc tggtttgcca 2300

 agtatgccag tgtaatgaaa ctgcccttat tttaaaagcc agtcaaagat 2350

 tccactgatt gacatttgat aaataaacat caggattatg tttattgttt 2400

 gttttcagtc tttgcactat attaccagta tatggtttcc gaggaagatt 2450

 atctactgca aaacaccact gttggaaaaa taggtatttt taaattgttt 2500

 ttaatccttt tttggtgctt ttaaacatgt ttaagcaaaa accaattcag 2550

 tccattcccc gcaaaaaacc cctaacttta ctctgaactt tttttgtttt 2600

 tgcattccat gaggttctgt attcagtcat tctctaggta atgtcatttt 2650

 tgtacacata tatttatata atcactgatt gagatttagg aaaaagcatt 2700

 tctaaagaat atttgcttcc cttagaacta cagactcgaa atctttaaag 2750

 atggtgccta agcatctatg tatttttttt aagttccaca gatttttctg 2800

 ttgggcaggc caaggattat aaaccacttc cctaaaggca acattaatgc 2850

 aaaagtcccc agatggcaat acaaagtatc ccctggtacc acatatattc 2900

 atttgtgagt ttggatatag agcacattat ctaaaccatt ttgtagttcc 2950

 aaaaacccat ctaaatttct tgagttcctg aattttgaac aggattacct 3000

 ggagcctgga gccactttaa gttgtacttc tgactaaact ggaattatga 3050

 gtgaggaaga gtgtttacta aataaatgac tggggcaagc aaaattgagg 3100

 aggaaattag aaactgtttg acaaacttta agagctactt gaaataacag 3150

 aagtcttgat taatatgcaa ataatggcta gaaagtatgg tttaactgga 3200

 ccctattatg ccttttaaaa ataatttcag taacccataa atacatgttg 3250

 taaaaaattc aaatatacag aatggaataa aaaaatgatc tccctttatt 3300

 accctcccaa aggttaccag cgtttgaatt taataatgta tattctttca 3350

 tgcttttttc tgtgcactta cctaagtgtg aatatgtaaa gggtttgttt 3400

 tgtatacaaa tgggattata ctaaaataag taatgcctat ttttaaggat 3450

 aggttaaatt tgtgaatgat catttcaaat atattgaata aaataagcaa 3500

 aagctattgt tatttactga tcctgaaaaa aaaaaaaaaa aaaaaaaaaa 3550

 aaaaaaaaaa aaaaaaaa 3568

<210> 472
<211> 599
<212> PRT
<213> Homo sapien

<400> 472
 Met Ala Asp Lys Leu Thr Arg Ile Ala Ile Val Asn His Asp Lys
   1               5                  10                  15

 Cys Lys Pro Lys Lys Cys Arg Gln Glu Cys Lys Lys Ser Cys Pro
                  20                  25                  30

 Val Val Arg Met Gly Lys Leu Cys Ile Glu Val Thr Pro Gln Ser
                  35                  40                  45

 Lys Ile Ala Trp Ile Ser Glu Thr Leu Cys Ile Gly Cys Gly Ile
                  50                  55                  60

 Cys Ile Lys Lys Cys Pro Phe Gly Ala Leu Ser Ile Val Asn Leu
                  65                  70                  75

 Pro Ser Asn Leu Glu Lys Glu Thr Thr His Arg Tyr Cys Ala Asn
                  80                  85                  90

 Ala Phe Lys Leu His Arg Leu Pro Ile Pro Arg Pro Gly Glu Val
                  95                 100                 105

 Leu Gly Leu Val Gly Thr Asn Gly Ile Gly Lys Ser Ala Ala Leu
                 110                 115                 120

 Lys Ile Leu Ala Gly Lys Gln Lys Pro Asn Leu Gly Lys Tyr Asp
                 125                 130                 135

 Asp Pro Pro Asp Trp Gln Glu Ile Leu Thr Tyr Phe Arg Gly Ser
                 140                 145                 150

 Glu Leu Gln Asn Tyr Phe Thr Lys Ile Leu Glu Asp Asp Leu Lys
                 155                 160                 165

 Ala Ile Ile Lys Pro Gln Tyr Val Ala Arg Phe Leu Arg Leu Ala
                 170                 175                 180

 Lys Gly Thr Val Gly Ser Ile Leu Asp Arg Lys Asp Glu Thr Lys
                 185                 190                 195

 Thr Gln Ala Ile Val Cys Gln Gln Leu Asp Leu Thr His Leu Lys
                 200                 205                 210

 Glu Arg Asn Val Glu Asp Leu Ser Gly Gly Glu Leu Gln Arg Phe
                 215                 220                 225

 Ala Cys Ala Val Val Cys Ile Gln Lys Ala Asp Ile Phe Met Phe
                 230                 235                 240

 Asp Glu Pro Ser Ser Tyr Leu Asp Val Lys Gln Arg Leu Lys Ala
                 245                 250                 255

 Ala Ile Thr Ile Arg Ser Leu Ile Asn Pro Asp Arg Tyr Ile Ile
                 260                 265                 270

 Val Val Glu His Asp Leu Ser Val Leu Asp Tyr Leu Ser Asp Phe
                 275                 280                 285

 Ile Cys Cys Leu Tyr Gly Val Pro Ser Ala Tyr Gly Val Val Thr
                 290                 295                 300

 Met Pro Phe Ser Val Arg Glu Gly Ile Asn Ile Phe Leu Asp Gly
                 305                 310                 315

 Tyr Val Pro Thr Glu Asn Leu Arg Phe Arg Asp Ala Ser Leu Val
                 320                 325                 330

 Phe Lys Val Ala Glu Thr Ala Asn Glu Glu Glu Val Lys Lys Met
                 335                 340                 345

 Cys Met Tyr Lys Tyr Pro Gly Met Lys Lys Lys Met Gly Glu Phe
                 350                 355                 360

 Glu Leu Ala Ile Val Ala Gly Glu Phe Thr Asp Ser Glu Ile Met
                 365                 370                 375

 Val Met Leu Gly Glu Asn Gly Thr Gly Lys Thr Thr Phe Ile Arg
                 380                 385                 390

 Met Leu Ala Gly Arg Leu Lys Pro Asp Glu Gly Gly Glu Val Pro
                 395                 400                 405

 Val Leu Asn Val Ser Tyr Lys Pro Gln Lys Ile Ser Pro Lys Ser
                 410                 415                 420

 Thr Gly Ser Val Arg Gln Leu Leu His Glu Lys Ile Arg Asp Ala
                 425                 430                 435

 Tyr Thr His Pro Gln Phe Val Thr Asp Val Met Lys Pro Leu Gln
                 440                 445                 450

 Ile Glu Asn Ile Ile Asp Gln Glu Val Gln Thr Leu Ser Gly Gly
                 455                 460                 465

 Glu Leu Gln Arg Val Arg Leu Arg Leu Cys Leu Gly Lys Pro Ala
                 470                 475                 480

 Asp Val Tyr Leu Ile Asp Glu Pro Ser Ala Tyr Leu Asp Ser Glu
                 485                 490                 495

 Gln Arg Leu Met Ala Ala Arg Val Val Lys Arg Phe Ile Leu His
                 500                 505                 510

 Ala Lys Lys Thr Ala Phe Val Val Glu His Asp Phe Ile Met Ala
                 515                 520                 525

 Thr Tyr Leu Ala Asp Arg Val Ile Val Phe Asp Gly Val Pro Ser
                 530                 535                 540

 Lys Asn Thr Val Ala Asn Ser Pro Gln Thr Leu Leu Ala Gly Met
                 545                 550                 555

 Asn Lys Phe Leu Ser Gln Leu Glu Ile Thr Phe Arg Arg Asp Pro
                 560                 565                 570

 Asn Asn Tyr Arg Pro Arg Ile Asn Lys Leu Asn Ser Ile Lys Asp
                 575                 580                 585

 Val Glu Gln Lys Lys Ser Gly Asn Tyr Phe Phe Leu Asp Asp
                 590                 595

<210> 473
<211> 4064
<212> DNA
<213> Homo sapien

<400> 473
 ctgcggccgc ctggtttctt gccttaagga gcccattgcc tttcccgctg 50

 aagtctagat gttgacatgt aataaagcgg gcagcaggat ggtggtggat 100

 gcggccaact ccaatgggcc tttccagccc gtggtccttc tccatattcg 150

 agatgttcct cctgctgatc aagagaagct ttttatccag aagttacgtc 200

 agtgttgcgt cctctttgac tttgtttctg atccactaag tgacctaaag 250

 tggaaggaag taaaacgagc tgctttaagt gaaatggtag aatatatcac 300

 ccataatcgg aatgtgatca cagagcctat ttacccagaa gtagtccata 350

 tgtttgcagt taacatgttt cgaacattac caccttcctc caatcctacg 400

 ggagcggaat ttgacccgga ggaagatgaa ccaacgttag aagcagcctg 450

 gcctcatcta cagcttgttt atgaattttt cttaagattt ttagagtctc 500

 cagatttcca acctaatata gcgaagaaat atattgatca gaagtttgta 550

 ttgcagcttt tagagctctt tgacagtgaa gatcctcggg agagagattt 600

 tcttaaaacc acccttcaca gaatctatgg gaaattccta ggcttgagag 650

 cttacatcag aaaacagata aataatatat tttataggtt tatttatgaa 700

 acagagcatc ataatggcat agcagagtta ctggaaatat tgggaagtat 750

 aattaatgga tttgccttac cactaaaaga agagcacaag attttcttat 800

 tgaaggtgtt actacctttg cacaaagtga aatctctgag tgtctaccat 850

 ccccagctgg catactgtgt agtgcagttt ttagaaaagg acagcaccct 900

 cacggaacca gtggtgatgg cacttctcaa atactggcca aagactcaca 950

 gtccaaaaga agtaatgttc ttaaacgaat tagaagagat tttagatgtc 1000

 attgaaccat cagaatttgt gaagatcatg gaacccctct tccggcagtt 1050

 ggccaaatgt gtctccagcc cacacttcca ggtggcagag cgagctctct 1100

 attactggaa taatgaatac atcatgagtt taatcagtga caacgcagcg 1150

 aagattctgc ccatcatgtt tccttccttg taccgcaact caaagaccca 1200

 ttggaacaag acaatacatg gcttgatata caacgccctg aagctcttca 1250

 tggagatgaa ccaaaagcta tttgatgact gtacacaaca gttcaaagca 1300

 gagaaactaa aagagaagct aaaaatgaaa gaacgggaag aagcatgggt 1350

 taaaatagaa aatctagcca aagccaatcc ccagtacaca gtgtatagtc 1400

 aagccagcac catgagcatt ccggttgcaa tggagacaga tgggccttta 1450

 tttgaagatg tgcagatgct gagaaagaca gtgaaggacg aggctcatca 1500

 ggcacagaaa gatccgaaga aggaccgtcc tcttgcactc cgcaagtccg 1550

 agctgcctca ggacccccac accaagaaag ccttggaagc tcactgcagg 1600

 gccgatgagc tggcctccca ggacggccgc tagcctccgg ggcgccgcgt 1650

 cggggccggg cccgccagtt cttttccgga ttctgtagaa aatacatact 1700

 tcctgtgcca taccaatcag ttacactcaa agctttcttg gaccccgttc 1750

 cgtaggcaat aacgtgcgtc cgcctcagcg cgagattagg agttcaaaca 1800

 atggtgactt cccagagccc gctggcagag ccgcgggttg acgacggtgt 1850

 cctcgcagtg tcgccgccac cccagcgtag tccaagtcag actatttcac 1900

 aaagtcagag cgataggaaa gcaccctgcc cttcatcttc atgttctccc 1950

 aaatggaact taggatcttt taacataggt ggttctgtga taacatcagt 2000

 gttttccaaa tcaaaggaac gctttaaaaa ataggaccta ttttttaaga 2050

 ctttacagcc tttgaaatgg tttccacgtg attgttacgc cagcagttct 2100

 tttgtttgtt tttcaatctc agtgaaatgg ctctttgctt tcgagttctc 2150

 acgcaacgta ctgggcaaat gacaatcctc agccgctggt attttctaag 2200

 gggtctcttc actttgatga gtgacatgaa caccgtgtct ccttctcttg 2250

 tgtgtaccta aagccatatt tccaagtctg tggtactcca ggattccagg 2300

 agtaagcctg tagaagagat ttattttaaa agagattgct ctgaaattta 2350

 tcttaaaaga gcttgctctg tctaccttga cagaaattgg agttttaaaa 2400

 ttatgtgtta atatttttat ttgcagattt cgtttccgtc aacttaaaca 2450

 ttgttgccct tcaacaaggc tcttgaatta ataaaattat agtctctaag 2500

 aattccacat tttatggaaa gttagagcaa aatcattttg agttaagcca 2550

 gttcttagcc taatgcaaac tgcagcgcct ttaagcataa agtaacacaa 2600

 cagcattgca cggggccggc actgccgctg ccttcactga aggctgcagt 2650

 gctgttctga gagcttggag gaggcaccag cgaggatgac gtttagtgga 2700

 gctctttctg ttgaaaagag ctcacgttat caacaccttg taaggaaaat 2750

 acagtgtctg agttttcatc ggtcttcaca tgctgctata tattccacag 2800

 agttccttgc atgtactgag cttttgtttt agatggaata gcacaaggag 2850

 aaaaatcttt aaacttagtg ctttgtctat tctttatttc tctcagggtg 2900

 gccagtattt tgacttattt atcctgcttg aaagctactt gagatgtgta 2950

 ctgctattct aaacacgtga tctagtttct ttcatctctg gcataagatt 3000

 atataactta atgttaagtg tcttgaggca taaaagacaa aatgtggctt 3050

 attttaggat ctgttttttc atcgaggtct cgggtatcct ttcaaagata 3100

 gtgagaagca gacactgctc cttgtgcagc tctggtacct cctgcccact 3150

 gctgtcactt caagccactg gcaatgcttc tgtcctcgtg tcttggagga 3200

 aaatcacctg gggggagggg acttcttgtg gtaagagcaa gtgcaggtat 3250

 gaaatgcgaa gattgcccca gctaaaagtg gacaagtccg ctttgtgaga 3300

 tgaatacttc ctgagaaact tgacaagtat ctctccattt taccattatg 3350

 aaaactatca ttaaaaaaaa cagtttagat gccttctcct tttgagggaa 3400

 aaagggtgct ttttattgta taaagcagcg tcttatgtat tttgatatac 3450

 cattgtttga acttccgtct ttagctgata gattctcaaa tatccttgat 3500

 tttggatgtt cagtatgttt gtgagagagg tttctgggaa gactctcttt 3550

 ttgccctcgg gaaaaagcaa aatatcaatg tttgggtgac tgtgtaaagc 3600

 tcagtgtgta agaacatctt tttgtctagg ttttctttct gctctttatt 3650

 gaagacaaac actcaccaaa aagaaaaata aaagttttca gagaaactaa 3700

 ttttctttgg caagagtatt acttaatatt ttggcctcct aaagtttccc 3750

 tagttagtac tcggactcct gtgctaattg tcagcttaca tatcattgta 3800

 tagagactgt ttattctgta ccaaactgat ttcaaaagta ctacattgaa 3850

 aataaaccgg tgactgtttt tcttcataaa gttctgcgtt tggcatcttc 3900

 actctttcca aaatgtatct gtacatcaga aatgtcacta ttccaagtgt 3950

 ctttttagtg tggcctttag tatggcttcc ttttaatatt gtacatacat 4000

 tgtatctttg ttttatggta ataagtaata aaaatgtaga cttcaaaaaa 4050

 aaaagcggcc gcag 4064

<210> 474
<211> 514
<212> PRT
<213> Homo sapien

<400> 474
 Met Val Val Asp Ala Ala Asn Ser Asn Gly Pro Phe Gln Pro Val
   1               5                  10                  15

 Val Leu Leu His Ile Arg Asp Val Pro Pro Ala Asp Gln Glu Lys
                  20                  25                  30

 Leu Phe Ile Gln Lys Leu Arg Gln Cys Cys Val Leu Phe Asp Phe
                  35                  40                  45

 Val Ser Asp Pro Leu Ser Asp Leu Lys Trp Lys Glu Val Lys Arg
                  50                  55                  60

 Ala Ala Leu Ser Glu Met Val Glu Tyr Ile Thr His Asn Arg Asn
                  65                  70                  75

 Val Ile Thr Glu Pro Ile Tyr Pro Glu Val Val His Met Phe Ala
                  80                  85                  90

 Val Asn Met Phe Arg Thr Leu Pro Pro Ser Ser Asn Pro Thr Gly
                  95                 100                 105

 Ala Glu Phe Asp Pro Glu Glu Asp Glu Pro Thr Leu Glu Ala Ala
                 110                 115                 120

 Trp Pro His Leu Gln Leu Val Tyr Glu Phe Phe Leu Arg Phe Leu
                 125                 130                 135

 Glu Ser Pro Asp Phe Gln Pro Asn Ile Ala Lys Lys Tyr Ile Asp
                 140                 145                 150

 Gln Lys Phe Val Leu Gln Leu Leu Glu Leu Phe Asp Ser Glu Asp
                 155                 160                 165

 Pro Arg Glu Arg Asp Phe Leu Lys Thr Thr Leu His Arg Ile Tyr
                 170                 175                 180

 Gly Lys Phe Leu Gly Leu Arg Ala Tyr Ile Arg Lys Gln Ile Asn
                 185                 190                 195

 Asn Ile Phe Tyr Arg Phe Ile Tyr Glu Thr Glu His His Asn Gly
                 200                 205                 210

 Ile Ala Glu Leu Leu Glu Ile Leu Gly Ser Ile Ile Asn Gly Phe
                 215                 220                 225

 Ala Leu Pro Leu Lys Glu Glu His Lys Ile Phe Leu Leu Lys Val
                 230                 235                 240

 Leu Leu Pro Leu His Lys Val Lys Ser Leu Ser Val Tyr His Pro
                 245                 250                 255

 Gln Leu Ala Tyr Cys Val Val Gln Phe Leu Glu Lys Asp Ser Thr
                 260                 265                 270

 Leu Thr Glu Pro Val Val Met Ala Leu Leu Lys Tyr Trp Pro Lys
                 275                 280                 285

 Thr His Ser Pro Lys Glu Val Met Phe Leu Asn Glu Leu Glu Glu
                 290                 295                 300

 Ile Leu Asp Val Ile Glu Pro Ser Glu Phe Val Lys Ile Met Glu
                 305                 310                 315

 Pro Leu Phe Arg Gln Leu Ala Lys Cys Val Ser Ser Pro His Phe
                 320                 325                 330

 Gln Val Ala Glu Arg Ala Leu Tyr Tyr Trp Asn Asn Glu Tyr Ile
                 335                 340                 345

 Met Ser Leu Ile Ser Asp Asn Ala Ala Lys Ile Leu Pro Ile Met
                 350                 355                 360

 Phe Pro Ser Leu Tyr Arg Asn Ser Lys Thr His Trp Asn Lys Thr
                 365                 370                 375

 Ile His Gly Leu Ile Tyr Asn Ala Leu Lys Leu Phe Met Glu Met
                 380                 385                 390

 Asn Gln Lys Leu Phe Asp Asp Cys Thr Gln Gln Phe Lys Ala Glu
                 395                 400                 405

 Lys Leu Lys Glu Lys Leu Lys Met Lys Glu Arg Glu Glu Ala Trp
                 410                 415                 420

 Val Lys Ile Glu Asn Leu Ala Lys Ala Asn Pro Gln Tyr Thr Val
                 425                 430                 435

 Tyr Ser Gln Ala Ser Thr Met Ser Ile Pro Val Ala Met Glu Thr
                 440                 445                 450

 Asp Gly Pro Leu Phe Glu Asp Val Gln Met Leu Arg Lys Thr Val
                 455                 460                 465

 Lys Asp Glu Ala His Gln Ala Gln Lys Asp Pro Lys Lys Asp Arg
                 470                 475                 480

 Pro Leu Ala Leu Arg Lys Ser Glu Leu Pro Gln Asp Pro His Thr
                 485                 490                 495

 Lys Lys Ala Leu Glu Ala His Cys Arg Ala Asp Glu Leu Ala Ser
                 500                 505                 510

 Gln Asp Gly Arg


<210> 475
<211> 2475
<212> DNA
<213> Homo sapien

<400> 475
 ccggaggagt ccgagaggaa gcggaggcgc gagctggagg cggcggctcc 50

 cgtcggcctc cggcaggact gagcgctggg aggccggaag gcgggcgcgc 100

 acggcggaga ggcgggcggg aggccggagc atattaatga aaagtgccat 150

 aaactgaaaa accaaacatg agggtagcag gtgctgcaaa gttggtggta 200

 gctgtggcag tgtttttact gacattttat gttatttctc aagtatttga 250

 aataaaaatg gatgcaagtt taggaaatct atttgcaaga tcagcattgg 300

 acacagctgc acgttctaca aagcctccca gatataagtg tgggatctca 350

 aaagcttgcc ctgagaagca ttttgctttt aaaatggcaa gtggagcagc 400

 caacgtggtg ggacccaaaa tctgcctgga agataatgtt ttaatgagtg 450

 gtgttaagaa taatgttgga agagggatca atgttgcctt ggcaaatgga 500

 aaaacaggag aagtattaga cactaaatat tttgacatgt ggggaggaga 550

 tgtggcacca tttattgagt ttctgaaggc catacaagat ggaacaatag 600

 ttttaatggg aacatacgat gatggagcaa ccaaactcaa tgatgaggca 650

 cggcggctca ttgctgattt ggggagcaca tctattacta atcttggttt 700

 tagagacaac tgggtcttct gtggtgggaa gggcattaag acaaaaagcc 750

 cttttgaaca gcacataaag aacaataagg atacaaacaa atatgaagga 800

 tggcctgaag ttgtagaaat ggaaggatgc atcccccaga agcaagacta 850

 atggaaatgt ggagagaatt gaagaaagcg cactttcact cttaatggga 900

 gagctataaa tggcagagct atgtgtaaat attttaagag catgcagcca 950

 tcttggtgtg tgcatgagta ttgtctcttt tgatatcagg attatttatt 1000

 gctaacgtaa atagatagca ttgtaaataa tcatcacaat gatcaaatca 1050

 ctgaaccatg tctccgcaca tttccctaaa agtacaatgt ttagactgct 1100

 atggtaatac atattttaaa ttctaaaagc atacacaatg tgtaactgaa 1150

 tggtttgtga aaaatatatt gatatatata ctagttgcta tgaaaatatc 1200

 atggaataat agggatttta gggtggatac tttattttct tttatgtttc 1250

 tatatgttgc gttgtgatga cattatcttt taaattaaaa agagatttgg 1300

 ctagttgtgt gtgtaatgtt actttacagt ccgactctcc tgatgtacct 1350

 cttttcatga tctttttctt tccttcccaa gaaactgagg aatgtttaat 1400

 atgaaaacat acatcggata tgtgaaaagc acaacaaaat tcttaatgta 1450

 cacagtaaaa aagtaaatat ataaatgtag atggcattta ggaccacagc 1500

 ttgctggatt tgtgttagct atgggaataa cttgattttg tataagctat 1550

 ttagagtgag gctggaggtg gcagcttcac agaactggag aaccaggcca 1600

 agtcccctcc ccaacctaat taggtcattc aggacagcta agtcagtata 1650

 tttagagcaa tactagcata cgtttttctt aattgttatc agcattgacc 1700

 aagtggtttg gaaggaggca tgctttaata tcacaataat tttgatttgt 1750

 aaaccaagaa attaatcctg tgtttatcta acttcataat agcaattatt 1800

 gcccgaagct atagtggcat atttacaaaa gttcttatta ctgggcggac 1850

 tgataacatt taaaaaataa ttgtgtttga ccccaaatga ctttataccc 1900

 aattctacat aaaaatatag aagatctatc tttttttgtt accttcagat 1950

 gttcactaaa taactcagtt tttaagcaga agttttcagg gcattaaata 2000

 tatgttgtgt atgaagtatc tcaaactgga acataaattt agtgatcaaa 2050

 ctgccattca cagtgtaagg cagcacttaa atttcgaacc taaagtttag 2100

 atgcattgta taaaaaaacc taaaagcagt atctgttatt tagctgtaaa 2150

 ccaagttgga agctattcgg ataatttctt aaatattgat gaactttgga 2200

 gtactgtttc ttccttcaaa ctgaatgtaa ttaattcatg aataaatgca 2250

 ccttatatgt ttaaacaatc tttgtatact tttgggattt ttggtgctta 2300

 tatgctaaat cacattcagc atgtgtattt tgacatttaa aatacttccc 2350

 tcaattctgt aaattaaaag aatagttatt ttacagttcc agggattgtg 2400

 aaataaatgt tgcagttttt taaaataatg aaaataaata ctcttggttt 2450

 tgctttgtga aaaaaaaaaa aaaaa 2475

<210> 476
<211> 227
<212> PRT
<213> Homo sapien

<400> 476
 Met Arg Val Ala Gly Ala Ala Lys Leu Val Val Ala Val Ala Val
   1               5                  10                  15

 Phe Leu Leu Thr Phe Tyr Val Ile Ser Gln Val Phe Glu Ile Lys
                  20                  25                  30

 Met Asp Ala Ser Leu Gly Asn Leu Phe Ala Arg Ser Ala Leu Asp
                  35                  40                  45

 Thr Ala Ala Arg Ser Thr Lys Pro Pro Arg Tyr Lys Cys Gly Ile
                  50                  55                  60

 Ser Lys Ala Cys Pro Glu Lys His Phe Ala Phe Lys Met Ala Ser
                  65                  70                  75

 Gly Ala Ala Asn Val Val Gly Pro Lys Ile Cys Leu Glu Asp Asn
                  80                  85                  90

 Val Leu Met Ser Gly Val Lys Asn Asn Val Gly Arg Gly Ile Asn
                  95                 100                 105

 Val Ala Leu Ala Asn Gly Lys Thr Gly Glu Val Leu Asp Thr Lys
                 110                 115                 120

 Tyr Phe Asp Met Trp Gly Gly Asp Val Ala Pro Phe Ile Glu Phe
                 125                 130                 135

 Leu Lys Ala Ile Gln Asp Gly Thr Ile Val Leu Met Gly Thr Tyr
                 140                 145                 150

 Asp Asp Gly Ala Thr Lys Leu Asn Asp Glu Ala Arg Arg Leu Ile
                 155                 160                 165

 Ala Asp Leu Gly Ser Thr Ser Ile Thr Asn Leu Gly Phe Arg Asp
                 170                 175                 180

 Asn Trp Val Phe Cys Gly Gly Lys Gly Ile Lys Thr Lys Ser Pro
                 185                 190                 195

 Phe Glu Gln His Ile Lys Asn Asn Lys Asp Thr Asn Lys Tyr Glu
                 200                 205                 210

 Gly Trp Pro Glu Val Val Glu Met Glu Gly Cys Ile Pro Gln Lys
                 215                 220                 225

 Gln Asp


<210> 477
<211> 2562
<212> DNA
<213> Homo sapien

<400> 477
 agaggctacc tatggtgaac gtgttgtagc ctttgctgca gtggaaggca 50

 ttttcttttc cggttctttt gcgtcgatat tctggctcaa gaaacgagga 100

 ctgatgcctg gcctcacatt ttctaatgaa cttattagca gagatgaggg 150

 tttacactgt gattttgctt gcctgatgtt caaacacctg gtacacaaac 200

 catcggagga gagagtaaga gaaataatta tcaatgctgt tcggatagaa 250

 caggagttcc tcactgaggc cttgcctgtg aagctcattg ggatgaattg 300

 cactctaatg aagcaataca ttgagtttgt ggcagacaga cttatgctgg 350

 aactgggttt tagcaaggtt ttcagagtag agaacccatt tgactttatg 400

 gagaatattt cactggaagg aaagactaac ttctttgaga agagagtagg 450

 cgagtatcag aggatgggag tgatgtcaag tccaacagag aattctttta 500

 ccttggatgc tgacttctaa atgaactgaa gatgtgccct tacttggctg 550

 attttttttt tccatctcat aagaaaaatc agctgaagtg ttaccaacta 600

 gccacaccat gaattgtccg taatgttcat taacagcatc tttaaaactg 650

 tgtagctacc tcacaaccag tcctgtctgt ttatagtgct ggtagtatca 700

 ccttttgcca gaaggcctgg ctggctgtga cttaccatag cagtgacaat 750

 ggcagtcttg gctttaaagt gaggggtgac cctttagtga gcttagcaca 800

 gcgggattaa acagtccttt aaccagcaca gccagttaaa agatgcagcc 850

 tcactgcttc aacgcagatt ttaatgttta cttaaatata aacctggcac 900

 tttacaaaca aataaacatt gtttgtactc acaaggcgat aatagcttga 950

 tttatttggt ttctacacca aatacattct cctgaccact aatgggagcc 1000

 aattcacaat tcactaagtg actaaagtaa gttaaacttg tgtagactaa 1050

 gcatgtaatt tttaagtttt attttaatga attaaaatat ttgttaacca 1100

 actttaaagt cagtcctgtg tatacctaga tattagtcag ttggtgccag 1150

 atagaagaca ggttgtgttt ttatcctgtg gcttgtgtag tgtcctggga 1200

 ttctctgccc cctctgagta gagtgttgtg ggataaagga atctctcagg 1250

 gcaaggagct tcttaagtta aatcactaga aatttagggg tgatctgggc 1300

 cttcatatgt gtgagaagcc gtttcatttt atttctcact gtattttcct 1350

 caacgtctgg ttgatgagaa aaaattcttg aagagttttc atatgtggga 1400

 gctaaggtag tattgtaaaa tttcaagtca tccttaaaca aaatgatcca 1450

 cctaagatct tgcccctgtt aagtggtgaa atcaactaga ggtggttcct 1500

 acaagttgtt cattctagtt ttgtttggtg taagtaggtt gtgtgagtta 1550

 attcatttat atttactatg tctgttaaat cagaaatttt ttattatcta 1600

 tgttcttcta gattttacct gtagttcata cttcagtcac ccagtgtctt 1650

 attctggcat tgtctaaatc tgagcattgt ctagggggat cttaaacttt 1700

 agtaggaaac catgagctgt taatacagtt tccattcaaa tattaatttc 1750

 agaatgaaac ataatttttt tttttttttt tgagatggag tctcgctctg 1800

 ttgcccaggc tggagtgcag tggcgcgatt ttggctcact gtaacctcca 1850

 tctcctgggt tcaagcaatt ctcctgtctc agcctcccta gtagctggga 1900

 ctgcaggtat gtgctaccac acctggctaa tttttgtatt tttagtagag 1950

 atggagtttc accatattgg ccaggctggt cttgaactcc tgacctcagg 2000

 tgatccaccc acctcggcct cccaaagtgc tgggattgca ggcgtgataa 2050

 acaaatattc ttaatagggc tactttgaat taatctgcct ttatgtttgg 2100

 gagaagaaag ctgagacatt gcatgaaaga tgatgagaga taaatgttga 2150

 tcttttggcc ccatttgtta attgtattca gtatttgaac gtcgtcctgt 2200

 ttattgttag ttttcttcat catttattgt atagacaatt tttaaatctc 2250

 tgtaatatga tacattttcc tatcttttaa gttattgtta cctaaagtta 2300

 atccagatta tatggtcctt atatgtgtac aacattaaaa tgaaaggctt 2350

 tgtcttgcat tgtgaggtac aggcggaagt tggaatcagg ttttaggatt 2400

 ctgtctctca ttagctgaat aatgtgagga ttaacttctg ccagctcaga 2450

 ccatttccta atcagttgaa agggaaacaa gtatttcagt ctcaaaattg 2500

 aataatgcac aagtcttaag tgattaaaat aaaactgttc ttatgtcaaa 2550

 aaaaaaaaaa aa 2562

<210> 478
<211> 1654
<212> DNA
<213> Homo sapien

<400> 478
 gaattcgggc ggtcctcgga gacacgcggc ggtgtcctgt gttggccatg 50

 gccgactacc tgattagtgg gggcacgtcc tacgtgccag acgacggact 100

 cacagcacag cagctcttca actgcggaga cggcctcacc tacaatgact 150

 ttctcattct ccctgggtac atcgacttca ctgcagacca ggtggacctg 200

 acttctgctc tgaccaagaa aatcactctt aagaccccac tggtttcctc 250

 tcccatggac acagtcacag aggctgggat ggccatagca atggcgctta 300

 caggcggtat tggcttcatc caccacaact gtacacctga attccaggcc 350

 aatgaagttc ggaaagtgaa gaaatatgaa cagggattca tcacagaccc 400

 tgtggtcctc agccccaagg atcgcgtgcg ggatgttttt gaggccaagg 450

 cccggcatgg tttctgcggt atcccaatca cagacacagg ccggatgggg 500

 agccgcttgg tgggcatcat ctcctccagg gacattgatt ttctcaaaga 550

 ggaggaacat gactgtttct tggaagagat aatgacaaag agggaagact 600

 tggtggtagc cccccgcagc atcacactga aggaggcaaa tgaaattctg 650

 cagcgcagca agaagggaaa gttgcccatt gtaaatgaag atgatgagct 700

 tgtggccatc attgcccgga cagacctgaa gaagaatcgg gactacccac 750

 tagcctccaa agatgccaag aaacagctgc tgtgtggggc agccattggc 800

 actcatgagg atgacaagta taggctggac ttgctcgccc aggctggtgt 850

 ggatgtagtg gttttggact cttcccaggg aaattccatc ttccagatca 900

 atatgatcaa gtacatcaaa gacaaatacc ctaatctcca agtcattgga 950

 ggcaatgtgg tcactgctgc ccaggccaag aacctcattg atgcaggtgt 1000

 ggatgccctg cgggtgggca tgggaagtgg ctccatctgc attacgcagg 1050

 aagtgctggc ctgtgggcgg ccccaagcaa cagcagtgta caaggtgtca 1100

 gagtatgcac ggcgctttgg tgttccggtc attgctgatg gaggaatcca 1150

 aaatgtgggt catattgcga aagccttggc ccttggggcc tccacagtca 1200

 tgatgggctc tctcctggct gccaccactg aggcccctgg tgaatacttc 1250

 ttttccgatg ggatccggct aaagaaatat cgcggtatgg gttctctcga 1300

 tgccatggac aagcacctca gcagccagaa cagatatttc agtgaagctg 1350

 acaaaatcaa agtggcccag ggagtgtctg gtgctgtgca ggacaaaggg 1400

 tcaatccaca aatttgtccc ttacctgatt gctggcatcc aacactcatg 1450

 ccaggacatt ggtgccaaga gcttgaccca agtccgagcc atgatgtact 1500

 ctggggagct taagtttgag aagagaacgt cctcagccca ggtggaaggt 1550

 ggcgtccata gcctccattc gtatgagaag cggcttttct gaaaagggat 1600

 ccagcacacc tcctcggttt ttttttcaat aaaagtttag aaagacccga 1650

 attc 1654

<210> 479
<211> 514
<212> PRT
<213> Homo sapien

<400> 479
 Met Ala Asp Tyr Leu Ile Ser Gly Gly Thr Ser Tyr Val Pro Asp
   1               5                  10                  15

 Asp Gly Leu Thr Ala Gln Gln Leu Phe Asn Cys Gly Asp Gly Leu
                  20                  25                  30

 Thr Tyr Asn Asp Phe Leu Ile Leu Pro Gly Tyr Ile Asp Phe Thr
                  35                  40                  45

 Ala Asp Gln Val Asp Leu Thr Ser Ala Leu Thr Lys Lys Ile Thr
                  50                  55                  60

 Leu Lys Thr Pro Leu Val Ser Ser Pro Met Asp Thr Val Thr Glu
                  65                  70                  75

 Ala Gly Met Ala Ile Ala Met Ala Leu Thr Gly Gly Ile Gly Phe
                  80                  85                  90

 Ile His His Asn Cys Thr Pro Glu Phe Gln Ala Asn Glu Val Arg
                  95                 100                 105

 Lys Val Lys Lys Tyr Glu Gln Gly Phe Ile Thr Asp Pro Val Val
                 110                 115                 120

 Leu Ser Pro Lys Asp Arg Val Arg Asp Val Phe Glu Ala Lys Ala
                 125                 130                 135

 Arg His Gly Phe Cys Gly Ile Pro Ile Thr Asp Thr Gly Arg Met
                 140                 145                 150

 Gly Ser Arg Leu Val Gly Ile Ile Ser Ser Arg Asp Ile Asp Phe
                 155                 160                 165

 Leu Lys Glu Glu Glu His Asp Cys Phe Leu Glu Glu Ile Met Thr
                 170                 175                 180

 Lys Arg Glu Asp Leu Val Val Ala Pro Arg Ser Ile Thr Leu Lys
                 185                 190                 195

 Glu Ala Asn Glu Ile Leu Gln Arg Ser Lys Lys Gly Lys Leu Pro
                 200                 205                 210

 Ile Val Asn Glu Asp Asp Glu Leu Val Ala Ile Ile Ala Arg Thr
                 215                 220                 225

 Asp Leu Lys Lys Asn Arg Asp Tyr Pro Leu Ala Ser Lys Asp Ala
                 230                 235                 240

 Lys Lys Gln Leu Leu Cys Gly Ala Ala Ile Gly Thr His Glu Asp
                 245                 250                 255

 Asp Lys Tyr Arg Leu Asp Leu Leu Ala Gln Ala Gly Val Asp Val
                 260                 265                 270

 Val Val Leu Asp Ser Ser Gln Gly Asn Ser Ile Phe Gln Ile Asn
                 275                 280                 285

 Met Ile Lys Tyr Ile Lys Asp Lys Tyr Pro Asn Leu Gln Val Ile
                 290                 295                 300

 Gly Gly Asn Val Val Thr Ala Ala Gln Ala Lys Asn Leu Ile Asp
                 305                 310                 315

 Ala Gly Val Asp Ala Leu Arg Val Gly Met Gly Ser Gly Ser Ile
                 320                 325                 330

 Cys Ile Thr Gln Glu Val Leu Ala Cys Gly Arg Pro Gln Ala Thr
                 335                 340                 345

 Ala Val Tyr Lys Val Ser Glu Tyr Ala Arg Arg Phe Gly Val Pro
                 350                 355                 360

 Val Ile Ala Asp Gly Gly Ile Gln Asn Val Gly His Ile Ala Lys
                 365                 370                 375

 Ala Leu Ala Leu Gly Ala Ser Thr Val Met Met Gly Ser Leu Leu
                 380                 385                 390

 Ala Ala Thr Thr Glu Ala Pro Gly Glu Tyr Phe Phe Ser Asp Gly
                 395                 400                 405

 Ile Arg Leu Lys Lys Tyr Arg Gly Met Gly Ser Leu Asp Ala Met
                 410                 415                 420

 Asp Lys His Leu Ser Ser Gln Asn Arg Tyr Phe Ser Glu Ala Asp
                 425                 430                 435

 Lys Ile Lys Val Ala Gln Gly Val Ser Gly Ala Val Gln Asp Lys
                 440                 445                 450

 Gly Ser Ile His Lys Phe Val Pro Tyr Leu Ile Ala Gly Ile Gln
                 455                 460                 465

 His Ser Cys Gln Asp Ile Gly Ala Lys Ser Leu Thr Gln Val Arg
                 470                 475                 480

 Ala Met Met Tyr Ser Gly Glu Leu Lys Phe Glu Lys Arg Thr Ser
                 485                 490                 495

 Ser Ala Gln Val Glu Gly Gly Val His Ser Leu His Ser Tyr Glu
                 500                 505                 510

 Lys Arg Leu Phe


<210> 480
<211> 717
<212> DNA
<213> Mus musculus

<400> 480
 agagcgatca tgtcgcacaa acaaatttac tattcggaca aatacgacga 50

 cgaggagttt gagtatcgac atgtcatgct gcccaaggac atagccaagc 100

 tggtccctaa aacccatctg atgtctgaat ctgaatggag gaatcttggc 150

 gttcagcaga gtcagggatg ggtccattat atgatccatg aaccagaacc 200

 tcacatcttg ctgttccggc gcccactacc caagaaacca aagaaatgaa 250

 gctggcaagc tacttttcag cctcaagctt tacacagctg tccttacttc 300

 ctaacatctt tctgataaca ttattatgtt gccttcttgt ttctcacttt 350

 gatatttaaa agatgttcaa tacactgttt gaatgtgctg gtaactgctt 400

 tgcttcttga gtagagccac caccaccata gcccagccag atgagtgctc 450

 tgtggaccca cagcctaagc tgagtgtgac cccagaagcc acgatgtgct 500

 ctgtatccag aacacacttg gcagatggag gaagcatctg agtttgagac 550

 catggctgtt acagggatca tgtaaacttg ctgtttttgt tttttctgcc 600

 gggtgttgta tgtgtggtga cttgcggatt tatgtttcag tgtactggaa 650

 actttccatt ttattcaaga aatctgttca tgttaaaagc cttgattaaa 700

 gaggaagttt ttataat 717

<210> 481
<211> 79
<212> PRT
<213> Mus musculus

<400> 481
 Met Ser His Lys Gln Ile Tyr Tyr Ser Asp Lys Tyr Asp Asp Glu
   1               5                  10                  15

 Glu Phe Glu Tyr Arg His Val Met Leu Pro Lys Asp Ile Ala Lys
                  20                  25                  30

 Leu Val Pro Lys Thr His Leu Met Ser Glu Ser Glu Trp Arg Asn
                  35                  40                  45

 Leu Gly Val Gln Gln Ser Gln Gly Trp Val His Tyr Met Ile His
                  50                  55                  60

 Glu Pro Glu Pro His Ile Leu Leu Phe Arg Arg Pro Leu Pro Lys
                  65                  70                  75

 Lys Pro Lys Lys


<210> 482
<211> 1985
<212> DNA
<213> Homo sapien

<400> 482
 tactgacttt cagcaccaac ttgtggtccc aggtaagttt ccacgctggt 50

 actttagccc tgggctcgaa cctgcggaca cgctgtggct gcaactcccc 100

 gcccgccaga cctcagtacg cagcgcggct ggtgagaaac ataatgcact 150

 ctgacttcca cgcgtggaat ggggagatgg actgcacggc gggcggacct 200

 gctcgggctg atggacggca ggtggactga tgtgcgcagg gactggcggc 250

 agcgcggtca gagccagtca gccaaagcca ggccagcaca atagactgtc 300

 ccggttcccg ccaggaggcg gccgagcacc aactgtacgg tactgcgcct 350

 gcgccgcgac cgccaacgcg cccagtctac gcttgcgcgg cgcaacaggg 400

 ccgactgcag ctggaagatg gcggcgtccg tggtctgtcg ggccgctacc 450

 gccggggcac aagtgctatt gcgcgcccgc cgctcgccgg ccctgctgcg 500

 gacgccagcc ttgcggagta cggcaacctt cgctcaggcg ctccagttcg 550

 tgccggagac gcaggttagc ctgctggaca acggcctgcg tgtggcctcc 600

 gagcagtcct ctcagcccac ttgcacggtg ggagtgtgga ttgatgttgg 650

 cagccgtttt gagactgaga agaataatgg ggcaggctac tttttggagc 700

 atctggcttt caagggaaca aagaatcggc ctggcagtgc cctggagaag 750

 gaggtggaga gcatgggggc ccatcttaat gcctacagca cccgggagca 800

 cacagcttac tacatcaagg cgctgtccaa ggatctgccg aaagctgtgg 850

 agctcctggg tgacattgtg cagaactgta gtctggaaga ctcacagatt 900

 gagaaggaac gtgatgtgat cctgcgggag atgcaggaga atgatgcatc 950

 tatgcgagat gtggtcttta actacctgca tgccacagca ttccagggca 1000

 cacctctagc ccaggctgtg gaggggccca gtgagaatgt caggaagctg 1050

 tctcgtgcag acttgaccga gtacctcagc acacattaca aggcccctcg 1100

 aatggtgctg gcagcagctg gaggagtgga gcaccagcaa ctgttagacc 1150

 tcgcccagaa gcacctcggt ggcatcccat ggacatatgc agaggacgct 1200

 gtgcccactc ttactccatg ccgcttcact ggcagtgaga tccgccaccg 1250

 tgatgatgct ctaccttttg cccacgtggc cattgcagta gagggtcctg 1300

 gctgggccag cccggacagt gtggccttgc aagtggccaa tgccatcatc 1350

 ggccactatg actgcactta tggtggtggc gtgcacctgt ccagcccact 1400

 ggcttcaggt gctgtggcca acaagctatg ccagagtttc cagaccttca 1450

 gcatctgcta tgcagagacg ggcttgctgg gtgcacactt tgtctgtgac 1500

 cgaatgaaaa tcgatgacat gatgttcgtc ctgcaagggc agtggatgcg 1550

 cctgtgtacc agtgccacgg agagtgaggt ggcccggggc aaaaacatcc 1600

 tcagaaatgc cctggtatct catctagatg gcactactcc tgtgtgtgag 1650

 gacatcggac gcagcctcct gacctatggc cgccgcatcc ccctggctga 1700

 atgggaaagc cggattgcgg aggtggatgc cagtgtggta cgtgagatct 1750

 gctccaagta catctatgac cagtgcccag cagtggctgg atatggcccc 1800

 attgagcagc tcccagacta caaccggatc cgtagcggca tgttctggct 1850

 gcgcttctag gcgggaagcc tatgtaagca agagggcagg gccggggttt 1900

 gtggtccccc ccccaccaca aacacagcac ttcggctcct ctaacctgtg 1950

 ccacaggtga ccaccaataa aatcctctgc tgaga 1985

<210> 483
<211> 480
<212> PRT
<213> Homo sapien

<400> 483
 Met Ala Ala Ser Val Val Cys Arg Ala Ala Thr Ala Gly Ala Gln
   1               5                  10                  15

 Val Leu Leu Arg Ala Arg Arg Ser Pro Ala Leu Leu Arg Thr Pro
                  20                  25                  30

 Ala Leu Arg Ser Thr Ala Thr Phe Ala Gln Ala Leu Gln Phe Val
                  35                  40                  45

 Pro Glu Thr Gln Val Ser Leu Leu Asp Asn Gly Leu Arg Val Ala
                  50                  55                  60

 Ser Glu Gln Ser Ser Gln Pro Thr Cys Thr Val Gly Val Trp Ile
                  65                  70                  75

 Asp Val Gly Ser Arg Phe Glu Thr Glu Lys Asn Asn Gly Ala Gly
                  80                  85                  90

 Tyr Phe Leu Glu His Leu Ala Phe Lys Gly Thr Lys Asn Arg Pro
                  95                 100                 105

 Gly Ser Ala Leu Glu Lys Glu Val Glu Ser Met Gly Ala His Leu
                 110                 115                 120

 Asn Ala Tyr Ser Thr Arg Glu His Thr Ala Tyr Tyr Ile Lys Ala
                 125                 130                 135

 Leu Ser Lys Asp Leu Pro Lys Ala Val Glu Leu Leu Gly Asp Ile
                 140                 145                 150

 Val Gln Asn Cys Ser Leu Glu Asp Ser Gln Ile Glu Lys Glu Arg
                 155                 160                 165

 Asp Val Ile Leu Arg Glu Met Gln Glu Asn Asp Ala Ser Met Arg
                 170                 175                 180

 Asp Val Val Phe Asn Tyr Leu His Ala Thr Ala Phe Gln Gly Thr
                 185                 190                 195

 Pro Leu Ala Gln Ala Val Glu Gly Pro Ser Glu Asn Val Arg Lys
                 200                 205                 210

 Leu Ser Arg Ala Asp Leu Thr Glu Tyr Leu Ser Thr His Tyr Lys
                 215                 220                 225

 Ala Pro Arg Met Val Leu Ala Ala Ala Gly Gly Val Glu His Gln
                 230                 235                 240

 Gln Leu Leu Asp Leu Ala Gln Lys His Leu Gly Gly Ile Pro Trp
                 245                 250                 255

 Thr Tyr Ala Glu Asp Ala Val Pro Thr Leu Thr Pro Cys Arg Phe
                 260                 265                 270

 Thr Gly Ser Glu Ile Arg His Arg Asp Asp Ala Leu Pro Phe Ala
                 275                 280                 285

 His Val Ala Ile Ala Val Glu Gly Pro Gly Trp Ala Ser Pro Asp
                 290                 295                 300

 Ser Val Ala Leu Gln Val Ala Asn Ala Ile Ile Gly His Tyr Asp
                 305                 310                 315

 Cys Thr Tyr Gly Gly Gly Val His Leu Ser Ser Pro Leu Ala Ser
                 320                 325                 330

 Gly Ala Val Ala Asn Lys Leu Cys Gln Ser Phe Gln Thr Phe Ser
                 335                 340                 345

 Ile Cys Tyr Ala Glu Thr Gly Leu Leu Gly Ala His Phe Val Cys
                 350                 355                 360

 Asp Arg Met Lys Ile Asp Asp Met Met Phe Val Leu Gln Gly Gln
                 365                 370                 375

 Trp Met Arg Leu Cys Thr Ser Ala Thr Glu Ser Glu Val Ala Arg
                 380                 385                 390

 Gly Lys Asn Ile Leu Arg Asn Ala Leu Val Ser His Leu Asp Gly
                 395                 400                 405

 Thr Thr Pro Val Cys Glu Asp Ile Gly Arg Ser Leu Leu Thr Tyr
                 410                 415                 420

 Gly Arg Arg Ile Pro Leu Ala Glu Trp Glu Ser Arg Ile Ala Glu
                 425                 430                 435

 Val Asp Ala Ser Val Val Arg Glu Ile Cys Ser Lys Tyr Ile Tyr
                 440                 445                 450

 Asp Gln Cys Pro Ala Val Ala Gly Tyr Gly Pro Ile Glu Gln Leu
                 455                 460                 465

 Pro Asp Tyr Asn Arg Ile Arg Ser Gly Met Phe Trp Leu Arg Phe
                 470                 475                 480

<210> 484
<211> 931
<212> DNA
<213> Homo sapien

<400> 484
 cagagtttcg ccatggcccg gggccccaag aagcacttaa agcgtgttgc 50

 agcgccgaag cattggatgc ttgacaaact aacgggtgta tttgcacctc 100

 gtccatcgac aggtccccac aagctgaggg aatgtcttcc tctgatcgtc 150

 ttcctcagga atagactcaa gtatgcgttg actggagatg aggtaaagaa 200

 gatatgtatg caacgtttca tcaaaattga tggcaaggtt cgagtggatg 250

 tcacataccc tgctggattc atggatgtca tcagcatcga gaagacaggt 300

 gaacatttcc gcctggtcta tgacaccaag ggccgttttg ctgttcaccg 350

 catcacagtg gaagaggcaa agtacaagtt gtgcaaagtg aggaagatta 400

 ctgtgggagt gaagggaatc cctcacctgg tgactcatga tgctcgaacc 450

 atccgctacc cagatcctgt catcaaggtg aacgatactg tgcagattga 500

 tttagggact ggcaagataa tcaactttat caaatttgat acaggcaatt 550

 tgtgtatggt gattggtgga gccaacctcg gtcgtgttgg tgtgatcacc 600

 aacagggaaa gacatcctgg ttcttttgat gtggtgcatg tgaaggatgc 650

 caatggcaac agctttgcca cgaggctttc caacattttt gtcattggca 700

 atggcaataa accttggatt tccctgccca ggggaaaggg cattcgactt 750

 actgttgctg aagagagaga taagaggctg gccaccaaac agagcagtgg 800

 ctaaattgca gtagcagcat atcttttttt ctttgcacaa ataaacagtg 850

 aattctcgtt taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 931

<210> 485
<211> 263
<212> PRT
<213> Homo sapien

<400> 485
 Met Ala Arg Gly Pro Lys Lys His Leu Lys Arg Val Ala Ala Pro
   1               5                  10                  15

 Lys His Trp Met Leu Asp Lys Leu Thr Gly Val Phe Ala Pro Arg
                  20                  25                  30

 Pro Ser Thr Gly Pro His Lys Leu Arg Glu Cys Leu Pro Leu Ile
                  35                  40                  45

 Val Phe Leu Arg Asn Arg Leu Lys Tyr Ala Leu Thr Gly Asp Glu
                  50                  55                  60

 Val Lys Lys Ile Cys Met Gln Arg Phe Ile Lys Ile Asp Gly Lys
                  65                  70                  75

 Val Arg Val Asp Val Thr Tyr Pro Ala Gly Phe Met Asp Val Ile
                  80                  85                  90

 Ser Ile Glu Lys Thr Gly Glu His Phe Arg Leu Val Tyr Asp Thr
                  95                 100                 105

 Lys Gly Arg Phe Ala Val His Arg Ile Thr Val Glu Glu Ala Lys
                 110                 115                 120

 Tyr Lys Leu Cys Lys Val Arg Lys Ile Thr Val Gly Val Lys Gly
                 125                 130                 135

 Ile Pro His Leu Val Thr His Asp Ala Arg Thr Ile Arg Tyr Pro
                 140                 145                 150

 Asp Pro Val Ile Lys Val Asn Asp Thr Val Gln Ile Asp Leu Gly
                 155                 160                 165

 Thr Gly Lys Ile Ile Asn Phe Ile Lys Phe Asp Thr Gly Asn Leu
                 170                 175                 180

 Cys Met Val Ile Gly Gly Ala Asn Leu Gly Arg Val Gly Val Ile
                 185                 190                 195

 Thr Asn Arg Glu Arg His Pro Gly Ser Phe Asp Val Val His Val
                 200                 205                 210

 Lys Asp Ala Asn Gly Asn Ser Phe Ala Thr Arg Leu Ser Asn Ile
                 215                 220                 225

 Phe Val Ile Gly Asn Gly Asn Lys Pro Trp Ile Ser Leu Pro Arg
                 230                 235                 240

 Gly Lys Gly Ile Arg Leu Thr Val Ala Glu Glu Arg Asp Lys Arg
                 245                 250                 255

 Leu Ala Thr Lys Gln Ser Ser Gly
                 260

<210> 486
<211> 2587
<212> DNA
<213> Homo sapien

<400> 486
 ggcacacacg aggaggaggg ttgagctgct gccgccgccg cctctgtcgt 50

 cgtcgcgagt gtggagtcgg gactggagct gctgccgcgg cgacgccggg 100

 gatctttgtc gctagctccc ggcccttctg ccccgccgcc ttccctcagt 150

 cagcgttgcc cactcctctc cggccgggcg cccctgcctc catttctcgc 200

 tctctgtcca ccacacacac ggcccccccg atcatggatc cgggcagtgg 250

 cggcggcggc ggcggcggcg gcggcggcgg gagcagcagc ggcagcagca 300

 gcagcgactc ggcgcctgac tgctgggacc aggcggacat ggaagccccc 350

 gggccgggcc cttgcggcgg cggcggcttc cctggcggcg gcggccgagg 400

 cccagcggga gaacctcagc gcggccttca gccggcaact caacgtcaac 450

 gccaagccct tcgtgcccaa cgtccacgcc gccgagttcg tgccgtcctt 500

 cctgcggggc ccggcagcgc cgccaccccc agctggcggc gccgccaata 550

 accacggagc cggcagcggc gcgggaggcc gtgcggcacc tgtggaatcc 600

 tctcaagagg aacagtcatt gtgtgaaggt tcaaattcag ctgttagcat 650

 ggaactttca gaacctattg tagaaaatgg agagacagaa atgtctccag 700

 aagaatcatg ggagcacaaa gaagaaataa gtgaagcaga gccagggggt 750

 ggttccttgg gagatggaag gccgccagag gaaagtgccc atgaaatgat 800

 ggaggaggaa gaggaaatcc caaaacctaa gtctgtggtt gcaccgccag 850

 gtgctcctaa gaaagagcat gtaaatgtag tattcattgg gcacgtagat 900

 gctggcaagt caaccattgg aggacaaata atgtatttga ctggaatggt 950

 tgacaaaagg acgcttgaaa agtatgaaag agaagctaaa gagaaaaaca 1000

 gagaaacttg gtacttgtct tgggccttag acacaaatca ggaagaacga 1050

 gacaagggta aaacagtaga agtgggtcgt gcctattttg aaaccgaaaa 1100

 gaagcatttc acaattctag atgcccctgg ccacaagagt tttgtcccaa 1150

 atatgattgg tggtgcctct caagctgatt tggctgtgct ggtaatctca 1200

 gccaggaaag gagagtttga aactggattt gaaaaaggag gacagacaag 1250

 agaacatgca atgttggcaa agacagcagg tgtaaaacac ctaattgtgc 1300

 taattaataa gatggatgat ccaacagtaa attggagcaa tgagagatat 1350

 gaagaatgta aggagaaact agtgccattt ttgaaaaaag ttggcttcaa 1400

 tcccaaaaag gacattcact ttatgccctg ctcaggactt actggagcaa 1450

 atctcaaaga gcagtcggat ttctgtcctt ggtacattgg attaccgttt 1500

 attccatatc tggataattt gccgaacttc aatagatcag ttgatggacc 1550

 aatcaggctg ccaattgtgg ataagtacaa ggatatgggc actgtggtcc 1600

 tgggaaagct ggaatcagga tctatttgta aaggccagca gcttgtgatg 1650

 atgccaaaca agcacaacgt ggaagttctt ggaatacttt ccgatgatgt 1700

 agagactgat accgtagccc caggtgaaaa cctcaaaatc agactgaaag 1750

 gaattgaaga agaggagatt cttccagggt ttatactttg tgatcctaat 1800

 aatctttgtc attctggacg cacatttgat gcccagatag tgattataga 1850

 gcacaaatcc atcatctgcc caggctataa tgcggtgctg catattcata 1900

 cctgtattga ggaggtggaa ataacagcct taatctgctt ggtagacaaa 1950

 aaatcaggag aaaaaagtaa gacccgaccc cgttttgtga aacaagatca 2000

 agtatgcatt gctcgcttaa ggacagcagg aaccatctgc cttgagacct 2050

 ttaaagactt ccctcagatg ggtcgtttca ccttaagaga tgagggtaag 2100

 accattgcaa ttggaaaagt tctgaaactg gttccagaga aagactaagc 2150

 attttcttga tgaccctgca caatactgtg aggaaaattg actgcagaag 2200

 cctacttcac accgccttct cttattttct gcccattgat aaacctctcc 2250

 ccatattttg caaagaggaa attcacagca aaagtccaca ttatgtcagc 2300

 tttctcatat tgagagctct gctatgccac tgttgaattt ttcccaagat 2350

 tcctgtccct agccctcact tcaaactctg cttccttgga cagatttggc 2400

 aatagctttg taagtgatgt ggacataatt gcctacaata atgaaaacct 2450

 acaggaattt ttttattttt cattttcccc ttaggcatat ttagtatttt 2500

 tcccccaggc cagatcattc gtgagtgtgc gagtgtgtgt gcacatgtta 2550

 caaaggcaac taccatgtta ataaaatatt caatttg 2587

<210> 487
<211> 499
<212> PRT
<213> Homo sapien

<400> 487
 Met Glu Leu Ser Glu Pro Ile Val Glu Asn Gly Glu Thr Glu Met
   1               5                  10                  15

 Ser Pro Glu Glu Ser Trp Glu His Lys Glu Glu Ile Ser Glu Ala
                  20                  25                  30

 Glu Pro Gly Gly Gly Ser Leu Gly Asp Gly Arg Pro Pro Glu Glu
                  35                  40                  45

 Ser Ala His Glu Met Met Glu Glu Glu Glu Glu Ile Pro Lys Pro
                  50                  55                  60

 Lys Ser Val Val Ala Pro Pro Gly Ala Pro Lys Lys Glu His Val
                  65                  70                  75

 Asn Val Val Phe Ile Gly His Val Asp Ala Gly Lys Ser Thr Ile
                  80                  85                  90

 Gly Gly Gln Ile Met Tyr Leu Thr Gly Met Val Asp Lys Arg Thr
                  95                 100                 105

 Leu Glu Lys Tyr Glu Arg Glu Ala Lys Glu Lys Asn Arg Glu Thr
                 110                 115                 120

 Trp Tyr Leu Ser Trp Ala Leu Asp Thr Asn Gln Glu Glu Arg Asp
                 125                 130                 135

 Lys Gly Lys Thr Val Glu Val Gly Arg Ala Tyr Phe Glu Thr Glu
                 140                 145                 150

 Lys Lys His Phe Thr Ile Leu Asp Ala Pro Gly His Lys Ser Phe
                 155                 160                 165

 Val Pro Asn Met Ile Gly Gly Ala Ser Gln Ala Asp Leu Ala Val
                 170                 175                 180

 Leu Val Ile Ser Ala Arg Lys Gly Glu Phe Glu Thr Gly Phe Glu
                 185                 190                 195

 Lys Gly Gly Gln Thr Arg Glu His Ala Met Leu Ala Lys Thr Ala
                 200                 205                 210

 Gly Val Lys His Leu Ile Val Leu Ile Asn Lys Met Asp Asp Pro
                 215                 220                 225

 Thr Val Asn Trp Ser Asn Glu Arg Tyr Glu Glu Cys Lys Glu Lys
                 230                 235                 240

 Leu Val Pro Phe Leu Lys Lys Val Gly Phe Asn Pro Lys Lys Asp
                 245                 250                 255

 Ile His Phe Met Pro Cys Ser Gly Leu Thr Gly Ala Asn Leu Lys
                 260                 265                 270

 Glu Gln Ser Asp Phe Cys Pro Trp Tyr Ile Gly Leu Pro Phe Ile
                 275                 280                 285

 Pro Tyr Leu Asp Asn Leu Pro Asn Phe Asn Arg Ser Val Asp Gly
                 290                 295                 300

 Pro Ile Arg Leu Pro Ile Val Asp Lys Tyr Lys Asp Met Gly Thr
                 305                 310                 315

 Val Val Leu Gly Lys Leu Glu Ser Gly Ser Ile Cys Lys Gly Gln
                 320                 325                 330

 Gln Leu Val Met Met Pro Asn Lys His Asn Val Glu Val Leu Gly
                 335                 340                 345

 Ile Leu Ser Asp Asp Val Glu Thr Asp Thr Val Ala Pro Gly Glu
                 350                 355                 360

 Asn Leu Lys Ile Arg Leu Lys Gly Ile Glu Glu Glu Glu Ile Leu
                 365                 370                 375

 Pro Gly Phe Ile Leu Cys Asp Pro Asn Asn Leu Cys His Ser Gly
                 380                 385                 390

 Arg Thr Phe Asp Ala Gln Ile Val Ile Ile Glu His Lys Ser Ile
                 395                 400                 405

 Ile Cys Pro Gly Tyr Asn Ala Val Leu His Ile His Thr Cys Ile
                 410                 415                 420

 Glu Glu Val Glu Ile Thr Ala Leu Ile Cys Leu Val Asp Lys Lys
                 425                 430                 435

 Ser Gly Glu Lys Ser Lys Thr Arg Pro Arg Phe Val Lys Gln Asp
                 440                 445                 450

 Gln Val Cys Ile Ala Arg Leu Arg Thr Ala Gly Thr Ile Cys Leu
                 455                 460                 465

 Glu Thr Phe Lys Asp Phe Pro Gln Met Gly Arg Phe Thr Leu Arg
                 470                 475                 480

 Asp Glu Gly Lys Thr Ile Ala Ile Gly Lys Val Leu Lys Leu Val
                 485                 490                 495

 Pro Glu Lys Asp


<210> 488
<211> 2001
<212> DNA
<213> Homo sapien

<400> 488
 gaagggcggc gcgcttaggc aggcggtggc gcggctggag tgccgcgggg 50

 agggctgtgc cggttgcttt ctgcagccgc atctcggcca gctctcctcg 100

 ccgtccccgg ggcgctgtgc gtctccagtc cgggaccgaa gccgcctgcc 150

 gtagcgggcg gccagatccg cgtcccgcct cagcggccgg aggacatgcg 200

 ggagagagaa tgagccagag ggacacgctg gtgcatctgt ttgccggagg 250

 atgtggtggt acagtgggag ctattctgac atgtccactg gaagttgtaa 300

 aaacacgact gcagtcatct tctgtgacgc tttatatttc tgaagttcag 350

 ctgaacacca tggctggagc cagtgtcaac cgagtagtgt ctcccggacc 400

 tcttcattgc ctaaaggtga tcttggaaaa agaagggcct cgttccttgt 450

 ttagaggact aggccccaat ttagtggggg tagccccttc cagagcaata 500

 tactttgctg cttattcaaa ctgcaaggaa aagttgaatg atgtatttga 550

 tcctgattct acccaagtac atatgatttc agctgcaatg gcaggtttta 600

 ctgcaatcac agcaaccaac cccatttggc ttataaagac tcggttacag 650

 cttgatgcaa ggaaccgcgg ggaaaggcga atgggtgctt ttgaatgtgt 700

 tcgtaaagtg tatcagacag atggactaaa aggattttat aggggcatgt 750

 ctgcttcata tgctggtata tcagagactg ttatccattt tgttatttat 800

 gaaagtataa aacaaaaact actggaatat aagactgctt ctacaatgga 850

 aaatggtgaa gagtctgtga aagaagcatc agattttgtg ggaatgatgc 900

 tagctgctgc cacctcaaaa acttgtgcca caactatagc atatccacat 950

 gttgtaagaa caagactacg tgaagaggga acaaaataca gatctttttt 1000

 tcagactcta tctttgcttg ttcaagaaga aggttatggg tctctttatc 1050

 gtggtctgac aactcatcta gtgagacaga ttccaaacac agccattatg 1100

 atggccacct atgaattggt ggtttaccta ctcaatggat agcagcacga 1150

 ggactgctgt actgcaaaaa aagaagacca aaagattaca gtggaccatg 1200

 ggatacagaa gccagcatgg cagacagaag aaaaatagtt tgggaacatg 1250

 taactattct aagtggaagt tttgttgtag gaattatagt aatcacacca 1300

 cattacttgg cctttcggta atgtgaaaaa aaaaaaaaaa cctcagagcc 1350

 tccaaggaaa tgcctttaga agcactcctc tctcaaaatt gccattttct 1400

 ctaccatgtc ccccagacac agttgggttt tgttgattta tggcagtctt 1450

 ctaaacaaag ccatccttaa ttttacatac tgtattgtaa ctatccaaag 1500

 atagtattgg cagtcataaa tttataactt ctggcctttg tttaattcca 1550

 gtaaaataac agcaatgaca atgagatcgt cagtattatt ttcacatttc 1600

 cctgagagga cctggcacaa tattttaaat ttaattattt ggcagtagtc 1650

 actgtttttg acaaccaatg aaatagcgtc taaatatctt gtatattttt 1700

 tagcatcaaa atgttttggt ttccactgct gacaggtgct tgttgtttag 1750

 cctaatgtgg atatttaaat tgttaacata ccaaacacac atggtaatag 1800

 tttgggacaa aataactagt aaaatgttga tttctcggct atttcactga 1850

 ctgcggcatg tcctcgtgtc ttctctgatt ttgtggtaca tgaatgaatg 1900

 catttatctt tttagtgact tactagttac gaacttgaat tatcacctct 1950

 ttgtcatact taagtatcat ttacataaag tgtaaaagat tttttcactt 2000

 t 2001

<210> 489
<211> 310
<212> PRT
<213> Homo sapien

<400> 489
 Met Ser Gln Arg Asp Thr Leu Val His Leu Phe Ala Gly Gly Cys
   1               5                  10                  15

 Gly Gly Thr Val Gly Ala Ile Leu Thr Cys Pro Leu Glu Val Val
                  20                  25                  30

 Lys Thr Arg Leu Gln Ser Ser Ser Val Thr Leu Tyr Ile Ser Glu
                  35                  40                  45

 Val Gln Leu Asn Thr Met Ala Gly Ala Ser Val Asn Arg Val Val
                  50                  55                  60

 Ser Pro Gly Pro Leu His Cys Leu Lys Val Ile Leu Glu Lys Glu
                  65                  70                  75

 Gly Pro Arg Ser Leu Phe Arg Gly Leu Gly Pro Asn Leu Val Gly
                  80                  85                  90

 Val Ala Pro Ser Arg Ala Ile Tyr Phe Ala Ala Tyr Ser Asn Cys
                  95                 100                 105

 Lys Glu Lys Leu Asn Asp Val Phe Asp Pro Asp Ser Thr Gln Val
                 110                 115                 120

 His Met Ile Ser Ala Ala Met Ala Gly Phe Thr Ala Ile Thr Ala
                 125                 130                 135

 Thr Asn Pro Ile Trp Leu Ile Lys Thr Arg Leu Gln Leu Asp Ala
                 140                 145                 150

 Arg Asn Arg Gly Glu Arg Arg Met Gly Ala Phe Glu Cys Val Arg
                 155                 160                 165

 Lys Val Tyr Gln Thr Asp Gly Leu Lys Gly Phe Tyr Arg Gly Met
                 170                 175                 180

 Ser Ala Ser Tyr Ala Gly Ile Ser Glu Thr Val Ile His Phe Val
                 185                 190                 195

 Ile Tyr Glu Ser Ile Lys Gln Lys Leu Leu Glu Tyr Lys Thr Ala
                 200                 205                 210

 Ser Thr Met Glu Asn Gly Glu Glu Ser Val Lys Glu Ala Ser Asp
                 215                 220                 225

 Phe Val Gly Met Met Leu Ala Ala Ala Thr Ser Lys Thr Cys Ala
                 230                 235                 240

 Thr Thr Ile Ala Tyr Pro His Val Val Arg Thr Arg Leu Arg Glu
                 245                 250                 255

 Glu Gly Thr Lys Tyr Arg Ser Phe Phe Gln Thr Leu Ser Leu Leu
                 260                 265                 270

 Val Gln Glu Glu Gly Tyr Gly Ser Leu Tyr Arg Gly Leu Thr Thr
                 275                 280                 285

 His Leu Val Arg Gln Ile Pro Asn Thr Ala Ile Met Met Ala Thr
                 290                 295                 300

 Tyr Glu Leu Val Val Tyr Leu Leu Asn Gly
                 305                 310

<210> 490
<211> 3220
<212> DNA
<213> Homo sapien

<400> 490
 gagctgtccc cggtgccgcc gacccgggcc gtgccgtgtg cccgtggctc 50

 cagccgctgc cgcctcgatc tcctcgtctc ccgctccgcc ctcccttttc 100

 cctggatgaa cttgcgtcct ttctcttctc cgccatggaa ttctgctccg 150

 tgcttttagc cctcctgagc caaagaaacc ccagacaaca gatgcccata 200

 cgcagcgtat agcagtaact ccccagctcg gtttctgtgc cgtagtttac 250

 agtatttaat tttatataat atatattatt tattatagca tttttgatac 300

 ctcatattct gtttacacat cttgaaaggc gctcagtagt tctcttacta 350

 aacaaccact actccagaga atggcaacgc tgattaccag tactacagct 400

 gctaccgccg cttctggtcc tttggtggac tacctatgga tgctcatcct 450

 gggcttcatt attgcatttg tcttggcatt ctccgtggga gccaatgatg 500

 tagcaaattc ttttggtaca gctgtgggct caggtgtagt gaccctgaag 550

 caagcctgca tcctagctag catctttgaa acagtgggct ctgtcttact 600

 gggggccaaa gtgagcgaaa ccatccggaa gggcttgatt gacgtggaga 650

 tgtacaactc gactcaaggg ctactgatgg ccggctcagt cagtgctatg 700

 tttggttctg ctgtgtggca actcgtggct tcgtttttga agctccctat 750

 ttctggaacc cattgtattg ttggtgcaac tattggtttc tccctcgtgg 800

 caaaggggca ggagggtgtc aagtggtctg aactgataaa aattgtgatg 850

 tcttggttcg tgtccccact gctttctgga attatgtctg gaattttatt 900

 cttcctggtt cgtgcattca tcctccataa ggcagatcca gttcctaatg 950

 gtttgcgagc tttgccagtt ttctatgcct gcacagttgg aataaacctc 1000

 ttttccatca tgtatactgg agcaccgttg ctgggctttg acaaacttcc 1050

 tctgtggggt accatcctca tctcggtggg atgtgcagtt ttctgtgccc 1100

 ttatcgtctg gttctttgta tgtcccagga tgaagagaaa aattgaacga 1150

 gaaataaagt gtagtccttc tgaaagcccc ttaatggaaa aaaagaatag 1200

 cttgaaagaa gaccatgaag aaacaaagtt gtctgttggt gatattgaaa 1250

 acaagcatcc tgtttctgag gtagggcctg ccactgtgcc cctccaggct 1300

 gtggtggagg agagaacagt ctcattcaaa cttggagatt tggaggaagc 1350

 tccagagaga gagaggcttc ccagcgtgga cttgaaagag gaaaccagca 1400

 tagatagcac cgtgaatggt gcagtgcagt tgcctaatgg gaaccttgtc 1450

 cagttcagtc aagccgtcag caaccaaata aactccagtg gccactccca 1500

 gtatcacacc gtgcataagg attccggcct gtacaaagag ctactccata 1550

 aattacatct tgccaaggtg ggagattgca tgggagactc cggtgacaaa 1600

 cccttaaggc gcaataatag ctatacttcc tataccatgg caatatgtgg 1650

 catgcctctg gattcattcc gtgccaaaga aggtgaacag aagggcgaag 1700

 aaatggagaa gctgacatgg cctaatgcag actccaagaa gcgaattcga 1750

 atggacagtt acaccagtta ctgcaatgct gtgtctgacc ttcactcagc 1800

 atctgagata gacatgagtg tcaaggcagc gatgggtcta ggtgacagaa 1850

 aaggaagtaa tggctctcta gaagaatggt atgaccagga taagcctgaa 1900

 gtctctctcc tcttccagtt cctgcagatc cttacagcct gctttgggtc 1950

 attcgcccat ggtggcaatg acgtaagcaa tgccattggg cctctggttg 2000

 ctttatattt ggtttatgac acaggagatg tttcttcaaa agtggcaaca 2050

 ccaatatggc ttctactcta tggtggtgtt ggtatctgtg ttggtctgtg 2100

 ggtttgggga agaagagtta tccagaccat ggggaaggat ctgacaccga 2150

 tcacaccctc tagtggcttc agtattgaac tggcatctgc cctcactgtg 2200

 gtgattgcat caaatattgg ccttcccatc agtacaacac attgtaaagt 2250

 gggctctgtt gtgtctgttg gctggctccg gtccaagaag gctgttgact 2300

 ggcgtctctt tcgtaacatt tttatggcct ggtttgtcac agtccccatt 2350

 tctggagtta tcagtgctgc catcatggca atcttcagat atgtcatcct 2400

 cagaatgtga agctgtttga gattaaaatt tgtgtcaatg tttgggacca 2450

 tcttaggtat tcctgctccc ctgaagaatg attacagtgt taacagaaga 2500

 ctgacaagag tctttttatt tgggagcaga ggagggaagt gttacttgtg 2550

 ctataactgc ttttgtgcta aatatgaatt gtctcaaaat tagctgtgta 2600

 aaatagcccg ggttccactg gctcctgctg aggtcccctt tccttctggg 2650

 ctgtgaattc ctgtacatat ttctctactt tttgtatcag gcttcaattc 2700

 cattatgttt taatgttgtc tctgaagatg acttgtgatt tttttttctt 2750

 ttttttaaac catgaagagc cgtttgacag agcatgctct gcgttgttgg 2800

 tttcaccagc ttctgccctc acatgcacag ggatttaaca acaaaaatat 2850

 aactacaact tcccttgtag tctcttatat aagtagagtc cttggtactc 2900

 tgccctcctg tcagtagtgg caggatctat tggcatattc gggagcttct 2950

 tagagggatg aggttctttg aacacagtga aaatttaaat tagtaacttt 3000

 tttgcaagca gtttattgac tgttattgct aagaagaagt aagaaagaaa 3050

 aagcctgttg gcaatcttgg ttatttcttt aagatttctg gcagtgtggg 3100

 atggatgaat gaagtggaat gtgaactttg ggcaagttaa atgggacagc 3150

 cttccatgtt catttgtcta cctcttaact gaataaaaaa gcctacagtt 3200

 tttagaaaaa acccgaattc 3220

<210> 491
<211> 679
<212> PRT
<213> Homo sapien

<400> 491
 Met Ala Thr Leu Ile Thr Ser Thr Thr Ala Ala Thr Ala Ala Ser
   1               5                  10                  15

 Gly Pro Leu Val Asp Tyr Leu Trp Met Leu Ile Leu Gly Phe Ile
                  20                  25                  30

 Ile Ala Phe Val Leu Ala Phe Ser Val Gly Ala Asn Asp Val Ala
                  35                  40                  45

 Asn Ser Phe Gly Thr Ala Val Gly Ser Gly Val Val Thr Leu Lys
                  50                  55                  60

 Gln Ala Cys Ile Leu Ala Ser Ile Phe Glu Thr Val Gly Ser Val
                  65                  70                  75

 Leu Leu Gly Ala Lys Val Ser Glu Thr Ile Arg Lys Gly Leu Ile
                  80                  85                  90

 Asp Val Glu Met Tyr Asn Ser Thr Gln Gly Leu Leu Met Ala Gly
                  95                 100                 105

 Ser Val Ser Ala Met Phe Gly Ser Ala Val Trp Gln Leu Val Ala
                 110                 115                 120

 Ser Phe Leu Lys Leu Pro Ile Ser Gly Thr His Cys Ile Val Gly
                 125                 130                 135

 Ala Thr Ile Gly Phe Ser Leu Val Ala Lys Gly Gln Glu Gly Val
                 140                 145                 150

 Lys Trp Ser Glu Leu Ile Lys Ile Val Met Ser Trp Phe Val Ser
                 155                 160                 165

 Pro Leu Leu Ser Gly Ile Met Ser Gly Ile Leu Phe Phe Leu Val
                 170                 175                 180

 Arg Ala Phe Ile Leu His Lys Ala Asp Pro Val Pro Asn Gly Leu
                 185                 190                 195

 Arg Ala Leu Pro Val Phe Tyr Ala Cys Thr Val Gly Ile Asn Leu
                 200                 205                 210

 Phe Ser Ile Met Tyr Thr Gly Ala Pro Leu Leu Gly Phe Asp Lys
                 215                 220                 225

 Leu Pro Leu Trp Gly Thr Ile Leu Ile Ser Val Gly Cys Ala Val
                 230                 235                 240

 Phe Cys Ala Leu Ile Val Trp Phe Phe Val Cys Pro Arg Met Lys
                 245                 250                 255

 Arg Lys Ile Glu Arg Glu Ile Lys Cys Ser Pro Ser Glu Ser Pro
                 260                 265                 270

 Leu Met Glu Lys Lys Asn Ser Leu Lys Glu Asp His Glu Glu Thr
                 275                 280                 285

 Lys Leu Ser Val Gly Asp Ile Glu Asn Lys His Pro Val Ser Glu
                 290                 295                 300

 Val Gly Pro Ala Thr Val Pro Leu Gln Ala Val Val Glu Glu Arg
                 305                 310                 315

 Thr Val Ser Phe Lys Leu Gly Asp Leu Glu Glu Ala Pro Glu Arg
                 320                 325                 330

 Glu Arg Leu Pro Ser Val Asp Leu Lys Glu Glu Thr Ser Ile Asp
                 335                 340                 345

 Ser Thr Val Asn Gly Ala Val Gln Leu Pro Asn Gly Asn Leu Val
                 350                 355                 360

 Gln Phe Ser Gln Ala Val Ser Asn Gln Ile Asn Ser Ser Gly His
                 365                 370                 375

 Ser Gln Tyr His Thr Val His Lys Asp Ser Gly Leu Tyr Lys Glu
                 380                 385                 390

 Leu Leu His Lys Leu His Leu Ala Lys Val Gly Asp Cys Met Gly
                 395                 400                 405

 Asp Ser Gly Asp Lys Pro Leu Arg Arg Asn Asn Ser Tyr Thr Ser
                 410                 415                 420

 Tyr Thr Met Ala Ile Cys Gly Met Pro Leu Asp Ser Phe Arg Ala
                 425                 430                 435

 Lys Glu Gly Glu Gln Lys Gly Glu Glu Met Glu Lys Leu Thr Trp
                 440                 445                 450

 Pro Asn Ala Asp Ser Lys Lys Arg Ile Arg Met Asp Ser Tyr Thr
                 455                 460                 465

 Ser Tyr Cys Asn Ala Val Ser Asp Leu His Ser Ala Ser Glu Ile
                 470                 475                 480

 Asp Met Ser Val Lys Ala Ala Met Gly Leu Gly Asp Arg Lys Gly
                 485                 490                 495

 Ser Asn Gly Ser Leu Glu Glu Trp Tyr Asp Gln Asp Lys Pro Glu
                 500                 505                 510

 Val Ser Leu Leu Phe Gln Phe Leu Gln Ile Leu Thr Ala Cys Phe
                 515                 520                 525

 Gly Ser Phe Ala His Gly Gly Asn Asp Val Ser Asn Ala Ile Gly
                 530                 535                 540

 Pro Leu Val Ala Leu Tyr Leu Val Tyr Asp Thr Gly Asp Val Ser
                 545                 550                 555

 Ser Lys Val Ala Thr Pro Ile Trp Leu Leu Leu Tyr Gly Gly Val
                 560                 565                 570

 Gly Ile Cys Val Gly Leu Trp Val Trp Gly Arg Arg Val Ile Gln
                 575                 580                 585

 Thr Met Gly Lys Asp Leu Thr Pro Ile Thr Pro Ser Ser Gly Phe
                 590                 595                 600

 Ser Ile Glu Leu Ala Ser Ala Leu Thr Val Val Ile Ala Ser Asn
                 605                 610                 615

 Ile Gly Leu Pro Ile Ser Thr Thr His Cys Lys Val Gly Ser Val
                 620                 625                 630

 Val Ser Val Gly Trp Leu Arg Ser Lys Lys Ala Val Asp Trp Arg
                 635                 640                 645

 Leu Phe Arg Asn Ile Phe Met Ala Trp Phe Val Thr Val Pro Ile
                 650                 655                 660

 Ser Gly Val Ile Ser Ala Ala Ile Met Ala Ile Phe Arg Tyr Val
                 665                 670                 675

 Ile Leu Arg Met


<210> 492
<211> 1470
<212> DNA
<213> Homo sapien

<400> 492
 agagccgcca gcgaggctgg ggatgggggc gccgctgctc tctcccggct 50

 ggggagccgg ggctgccggc cggcgctggt ggatgctgct ggcgcccctg 100

 ctgccggcgc tgctgctggt gcggcccgcg ggggccctgg tggaggggct 150

 ctactgcggc acgcgggact gctacgaggt gctgggcgtg agccgctcgg 200

 cgggcaaggc ggagatcgcg cgggcctacc gccagctggc ccggcgctac 250

 caccctgacc gctaccggcc ccagcccgga gacgagggcc ccgggcggac 300

 gccgcagagc gccgaggagg ctttcctgct ggtggcaacc gcctacgaga 350

 cactcaaggt ctctcaggca gctgcagagc ttcaacagta ctgtatgcag 400

 aatgcctgca aggatgccct gctggtgggt gttccagctg gaagtaaccc 450

 cttccgggag cctagatcct gtgctttact ctgaagactc gagagaagtt 500

 tgctgaggaa tgccttcaag cacaaagtga tgaatgactg ccttcaagtc 550

 tcaagaaaac acttttccct aacttttaga gatatttcag ccctttcctg 600

 tggcctggtc ctatagccaa aatcacagat attcatgagt ttctacttga 650

 gtgagaaaac tgggtgaagg aatagaattt taaatagtaa taactgcttg 700

 ttttttttgt gcaagtactt ttatacataa gataaacaaa aaccttacca 750

 ccaaacatac caaaatgcac ctctttcata agtgagttac taagatttct 800

 atacctggaa tatcatgtat gtttcattta ctggatgttt acattttagg 850

 aaggaaaata gttttgttta tttaaacaac tgaatactta taaactgttg 900

 ttcctggaag ttatttattc cataaaaaat ttgttctttt gtcatgaatt 950

 tataattcct aaatgaagac cagaaagtac aaattgctgg gaggaagaat 1000

 aggctttatt aatcaactga tgtcttgatt tttctaaatg ggaagattgc 1050

 tttattttta acactaatta tgggagcaga ttcttagcaa acttctttgg 1100

 aaaagttaat gttatgatgt gcattaggct gccccatcgt gtatataaat 1150

 gaagcagatt tgatttttgt attcttacgt ttctctgctt tgtagttgtg 1200

 gctgtactta aagaaataca gaatttcata tatttaaaaa tgtttaaaat 1250

 gtgacccaca gaacattgta aatgattaaa aactaacatg aaaatattac 1300

 aacctaaaag aattcttaac ttcacaagtg ttttacttcg acgatgtgcc 1350

 tttgatttaa tttgggacac ttttttagaa ggatacatta ttcgtgtttg 1400

 caacggtctt tgaagagctt ggaaataaaa tttctgctta attaatcaaa 1450

 aaaaaaaaaa aaaaaaaaaa 1470

<210> 493
<211> 153
<212> PRT
<213> Homo sapien

<400> 493
 Met Gly Ala Pro Leu Leu Ser Pro Gly Trp Gly Ala Gly Ala Ala
   1               5                  10                  15

 Gly Arg Arg Trp Trp Met Leu Leu Ala Pro Leu Leu Pro Ala Leu
                  20                  25                  30

 Leu Leu Val Arg Pro Ala Gly Ala Leu Val Glu Gly Leu Tyr Cys
                  35                  40                  45

 Gly Thr Arg Asp Cys Tyr Glu Val Leu Gly Val Ser Arg Ser Ala
                  50                  55                  60

 Gly Lys Ala Glu Ile Ala Arg Ala Tyr Arg Gln Leu Ala Arg Arg
                  65                  70                  75

 Tyr His Pro Asp Arg Tyr Arg Pro Gln Pro Gly Asp Glu Gly Pro
                  80                  85                  90

 Gly Arg Thr Pro Gln Ser Ala Glu Glu Ala Phe Leu Leu Val Ala
                  95                 100                 105

 Thr Ala Tyr Glu Thr Leu Lys Val Ser Gln Ala Ala Ala Glu Leu
                 110                 115                 120

 Gln Gln Tyr Cys Met Gln Asn Ala Cys Lys Asp Ala Leu Leu Val
                 125                 130                 135

 Gly Val Pro Ala Gly Ser Asn Pro Phe Arg Glu Pro Arg Ser Cys
                 140                 145                 150

 Ala Leu Leu


<210> 494
<211> 921
<212> DNA
<213> Homo sapien

<400> 494
 gcggcgctcg cgccaaggga cgtgtttctg cgctcgcgtg gtcatggagg 50

 cgctgccgct gctagccgcg acaactccgg accacggccg ccaccgaagg 100

 ctgcttctgc tgccgctact gctgttcctg ctgccggctg gagctgtgca 150

 gggctgggag acagaggaga ggccccggac tcgcgaagag gagtgccact 200

 tctacgcggg tggacaagtg tacccgggag aggcatcccg ggtatcggtc 250

 gccgaccact ccctgcacct aagcaaagcg aagatttcca agccagcgcc 300

 ctactgggaa ggaacagctg tgatcgatgg agaatttaag gagctgaagt 350

 taactgatta tcgtgggaaa tacttggttt tcttcttcta cccacttgat 400

 ttcacatttg tgtgtccaac tgaaattatc gcttttggcg acagacttga 450

 agaattcaga tctataaata ctgaagtggt agcatgctct gttgattcac 500

 agtttaccca tttggcctgg attaataccc ctcgaagaca aggaggactt 550

 gggccaataa ggattccact tctttcagat ttgacccatc agatctcaaa 600

 ggactatggt gtatacctag aggactcagg ccacactctt agaggtctct 650

 tcattattga tgacaaagga atcctaagac aaattactct gaatgatctt 700

 cctgtgggta gatcagtgga tgagacacta cgtttggttc aagcattcca 750

 gtacactgac aaacacggag aagtctgccc tgctggctgg aaacctggta 800

 gtgaaacaat aatcccagat ccagctggaa agctgaagta tttcgataaa 850

 ctgaattgag aaatacttct tcaagttatg atgcttgaaa gttctcaata 900

 aagttcacgg tttcattacc a 921

<210> 495
<211> 271
<212> PRT
<213> Homo sapien

<400> 495
 Met Glu Ala Leu Pro Leu Leu Ala Ala Thr Thr Pro Asp His Gly
   1               5                  10                  15

 Arg His Arg Arg Leu Leu Leu Leu Pro Leu Leu Leu Phe Leu Leu
                  20                  25                  30

 Pro Ala Gly Ala Val Gln Gly Trp Glu Thr Glu Glu Arg Pro Arg
                  35                  40                  45

 Thr Arg Glu Glu Glu Cys His Phe Tyr Ala Gly Gly Gln Val Tyr
                  50                  55                  60

 Pro Gly Glu Ala Ser Arg Val Ser Val Ala Asp His Ser Leu His
                  65                  70                  75

 Leu Ser Lys Ala Lys Ile Ser Lys Pro Ala Pro Tyr Trp Glu Gly
                  80                  85                  90

 Thr Ala Val Ile Asp Gly Glu Phe Lys Glu Leu Lys Leu Thr Asp
                  95                 100                 105

 Tyr Arg Gly Lys Tyr Leu Val Phe Phe Phe Tyr Pro Leu Asp Phe
                 110                 115                 120

 Thr Phe Val Cys Pro Thr Glu Ile Ile Ala Phe Gly Asp Arg Leu
                 125                 130                 135

 Glu Glu Phe Arg Ser Ile Asn Thr Glu Val Val Ala Cys Ser Val
                 140                 145                 150

 Asp Ser Gln Phe Thr His Leu Ala Trp Ile Asn Thr Pro Arg Arg
                 155                 160                 165

 Gln Gly Gly Leu Gly Pro Ile Arg Ile Pro Leu Leu Ser Asp Leu
                 170                 175                 180

 Thr His Gln Ile Ser Lys Asp Tyr Gly Val Tyr Leu Glu Asp Ser
                 185                 190                 195

 Gly His Thr Leu Arg Gly Leu Phe Ile Ile Asp Asp Lys Gly Ile
                 200                 205                 210

 Leu Arg Gln Ile Thr Leu Asn Asp Leu Pro Val Gly Arg Ser Val
                 215                 220                 225

 Asp Glu Thr Leu Arg Leu Val Gln Ala Phe Gln Tyr Thr Asp Lys
                 230                 235                 240

 His Gly Glu Val Cys Pro Ala Gly Trp Lys Pro Gly Ser Glu Thr
                 245                 250                 255

 Ile Ile Pro Asp Pro Ala Gly Lys Leu Lys Tyr Phe Asp Lys Leu
                 260                 265                 270

 Asn


<210> 496
<211> 2102
<212> DNA
<213> Homo sapien

<400> 496
 ccgctgggcg tagctgcgac tcggcggagt cccggcggcg cgtccttgtt 50

 ctaacccggc gcgccatgac cgtcgcgcgg ccgagcgtgc ccgcggcgct 100

 gcccctcctc ggggagctgc cccggctgct gctgctggtg ctgttgtgcc 150

 tgccggccgt gtggggtgac tgtggccttc ccccagatgt acctaatgcc 200

 cagccagctt tggaaggccg tacaagtttt cccgaggata ctgtaataac 250

 gtacaaatgt gaagaaagct ttgtgaaaat tcctggcgag aaggactcag 300

 tgatctgcct taagggcagt caatggtcag atattgaaga gttctgcaat 350

 cgtagctgcg aggtgccaac aaggctaaat tctgcatccc tcaaacagcc 400

 ttatatcact cagaattatt ttccagtcgg tactgttgtg gaatatgagt 450

 gccgtccagg ttacagaaga gaaccttctc tatcaccaaa actaacttgc 500

 cttcagaatt taaaatggtc cacagcagtc gaattttgta aaaagaaatc 550

 atgccctaat ccgggagaaa tacgaaatgg tcagattgat gtaccaggtg 600

 gcatattatt tggtgcaacc atctccttct catgtaacac agggtacaaa 650

 ttatttggct cgacttctag tttttgtctt atttcaggca gctctgtcca 700

 gtggagtgac ccgttgccag agtgcagaga aatttattgt ccagcaccac 750

 cacaaattga caatggaata attcaagggg aacgtgacca ttatggatat 800

 agacagtctg taacgtatgc atgtaataaa ggattcacca tgattggaga 850

 gcactctatt tattgtactg tgaataatga tgaaggagag tggagtggcc 900

 caccacctga atgcagagga aaatctctaa cttccaaggt cccaccaaca 950

 gttcagaaac ctaccacagt aaatgttcca actacagaag tctcaccaac 1000

 ttctcagaaa accaccacaa aaaccaccac accaaatgct caagcaacac 1050

 ggagtacacc tgtttccagg acaaccaagc attttcatga aacaacccca 1100

 aataaaggaa gtggaaccac ttcaggtact acccgtcttc tatctgggca 1150

 cacgtgtttc acgttgacag gtttgcttgg gacgctagta accatgggct 1200

 tgctgactta gccaaagaag agttaagaag aaaatacaca caagtataca 1250

 gactgttcct agtttcttag acttatctgc atattggata aaataaatgc 1300

 aattgtgctc ttcatttagg atgctttcat tgtctttaag atgtgttagg 1350

 aatgtcaaca gagcaaggag aaaaaaggca gtcctggaat cacattctta 1400

 gcacacctac acctcttgaa aatagaacaa cttgcagaat tgagagtgat 1450

 tcctttccta aaagtgtaag aaagcataga gatttgttcg tatttagaat 1500

 gggatcacga ggaaaagaga aggaaagtga tttttttcca caagatctgt 1550

 aatgttattt ccacttataa aggaaataaa aaatgaaaaa cattatttgg 1600

 atatcaaaag caaataaaaa cccaattcag tctcttctaa gcaaaattgc 1650

 taaagagaga tgaaccacat tataaagtaa tctttggctg taaggcattt 1700

 tcatctttcc ttcgggttgg caaaatattt taaaggtaaa acatgctggt 1750

 gaaccagggg tgttgatggt gataagggag gaatatagaa tgaaagactg 1800

 aatcttcctt tgttgcacaa atagagtttg gaaaaagcct gtgaaaggtg 1850

 tcttctttga cttaatgtct ttaaaagtat ccagagatac tacaatatta 1900

 acataagaaa agattatata ttatttctga atcgagatgt ccatagtcaa 1950

 atttgtaaat cttattcttt tgtaatattt atttatattt atttatgaca 2000

 gtgaacattc tgattttaca tgtaaaacaa gaaaagttga agaagatatg 2050

 tgaagaaaaa tgtatttttc ctaaatagaa ataaatgatc ccattttttg 2100

 gt 2102

<210> 497
<211> 381
<212> PRT
<213> Homo sapien

<400> 497
 Met Thr Val Ala Arg Pro Ser Val Pro Ala Ala Leu Pro Leu Leu
   1               5                  10                  15

 Gly Glu Leu Pro Arg Leu Leu Leu Leu Val Leu Leu Cys Leu Pro
                  20                  25                  30

 Ala Val Trp Gly Asp Cys Gly Leu Pro Pro Asp Val Pro Asn Ala
                  35                  40                  45

 Gln Pro Ala Leu Glu Gly Arg Thr Ser Phe Pro Glu Asp Thr Val
                  50                  55                  60

 Ile Thr Tyr Lys Cys Glu Glu Ser Phe Val Lys Ile Pro Gly Glu
                  65                  70                  75

 Lys Asp Ser Val Ile Cys Leu Lys Gly Ser Gln Trp Ser Asp Ile
                  80                  85                  90

 Glu Glu Phe Cys Asn Arg Ser Cys Glu Val Pro Thr Arg Leu Asn
                  95                 100                 105

 Ser Ala Ser Leu Lys Gln Pro Tyr Ile Thr Gln Asn Tyr Phe Pro
                 110                 115                 120

 Val Gly Thr Val Val Glu Tyr Glu Cys Arg Pro Gly Tyr Arg Arg
                 125                 130                 135

 Glu Pro Ser Leu Ser Pro Lys Leu Thr Cys Leu Gln Asn Leu Lys
                 140                 145                 150

 Trp Ser Thr Ala Val Glu Phe Cys Lys Lys Lys Ser Cys Pro Asn
                 155                 160                 165

 Pro Gly Glu Ile Arg Asn Gly Gln Ile Asp Val Pro Gly Gly Ile
                 170                 175                 180

 Leu Phe Gly Ala Thr Ile Ser Phe Ser Cys Asn Thr Gly Tyr Lys
                 185                 190                 195

 Leu Phe Gly Ser Thr Ser Ser Phe Cys Leu Ile Ser Gly Ser Ser
                 200                 205                 210

 Val Gln Trp Ser Asp Pro Leu Pro Glu Cys Arg Glu Ile Tyr Cys
                 215                 220                 225

 Pro Ala Pro Pro Gln Ile Asp Asn Gly Ile Ile Gln Gly Glu Arg
                 230                 235                 240

 Asp His Tyr Gly Tyr Arg Gln Ser Val Thr Tyr Ala Cys Asn Lys
                 245                 250                 255

 Gly Phe Thr Met Ile Gly Glu His Ser Ile Tyr Cys Thr Val Asn
                 260                 265                 270

 Asn Asp Glu Gly Glu Trp Ser Gly Pro Pro Pro Glu Cys Arg Gly
                 275                 280                 285

 Lys Ser Leu Thr Ser Lys Val Pro Pro Thr Val Gln Lys Pro Thr
                 290                 295                 300

 Thr Val Asn Val Pro Thr Thr Glu Val Ser Pro Thr Ser Gln Lys
                 305                 310                 315

 Thr Thr Thr Lys Thr Thr Thr Pro Asn Ala Gln Ala Thr Arg Ser
                 320                 325                 330

 Thr Pro Val Ser Arg Thr Thr Lys His Phe His Glu Thr Thr Pro
                 335                 340                 345

 Asn Lys Gly Ser Gly Thr Thr Ser Gly Thr Thr Arg Leu Leu Ser
                 350                 355                 360

 Gly His Thr Cys Phe Thr Leu Thr Gly Leu Leu Gly Thr Leu Val
                 365                 370                 375

 Thr Met Gly Leu Leu Thr
                 380

<210> 498
<211> 2102
<212> DNA
<213> Homo sapien

<400> 498
 ccgctgggcg tagctgcgac tcggcggagt cccggcggcg cgtccttgtt 50

 ctaacccggc gcgccatgac cgtcgcgcgg ccgagcgtgc ccgcggcgct 100

 gcccctcctc ggggagctgc cccggctgct gctgctggtg ctgttgtgcc 150

 tgccggccgt gtggggtgac tgtggccttc ccccagatgt acctaatgcc 200

 cagccagctt tggaaggccg tacaagtttt cccgaggata ctgtaataac 250

 gtacaaatgt gaagaaagct ttgtgaaaat tcctggcgag aaggactcag 300

 tgatctgcct taagggcagt caatggtcag atattgaaga gttctgcaat 350

 cgtagctgcg aggtgccaac aaggctaaat tctgcatccc tcaaacagcc 400

 ttatatcact cagaattatt ttccagtcgg tactgttgtg gaatatgagt 450

 gccgtccagg ttacagaaga gaaccttctc tatcaccaaa actaacttgc 500

 cttcagaatt taaaatggtc cacagcagtc gaattttgta aaaagaaatc 550

 atgccctaat ccgggagaaa tacgaaatgg tcagattgat gtaccaggtg 600

 gcatattatt tggtgcaacc atctccttct catgtaacac agggtacaaa 650

 ttatttggct cgacttctag tttttgtctt atttcaggca gctctgtcca 700

 gtggagtgac ccgttgccag agtgcagaga aatttattgt ccagcaccac 750

 cacaaattga caatggaata attcaagggg aacgtgacca ttatggatat 800

 agacagtctg taacgtatgc atgtaataaa ggattcacca tgattggaga 850

 gcactctatt tattgtactg tgaataatga tgaaggagag tggagtggcc 900

 caccacctga atgcagagga aaatctctaa cttccaaggt cccaccaaca 950

 gttcagaaac ctaccacagt aaatgttcca actacagaag tctcaccaac 1000

 ttctcagaaa accaccacaa aaaccaccac accaaatgct caagcaacac 1050

 ggagtacacc tgtttccagg acaaccaagc attttcatga aacaacccca 1100

 aataaaggaa gtggaaccac ttcaggtact acccgtcttc tatctgggca 1150

 cacgtgtttc acgttgacag gtttgcttgg gacgctagta accatgggct 1200

 tgctgactta gccaaagaag agttaagaag aaaatacaca caagtataca 1250

 gactgttcct agtttcttag acttatctgc atattggata aaataaatgc 1300

 aattgtgctc ttcatttagg atgctttcat tgtctttaag atgtgttagg 1350

 aatgtcaaca gagcaaggag aaaaaaggca gtcctggaat cacattctta 1400

 gcacacctac acctcttgaa aatagaacaa cttgcagaat tgagagtgat 1450

 tcctttccta aaagtgtaag aaagcataga gatttgttcg tatttagaat 1500

 gggatcacga ggaaaagaga aggaaagtga tttttttcca caagatctgt 1550

 aatgttattt ccacttataa aggaaataaa aaatgaaaaa cattatttgg 1600

 atatcaaaag caaataaaaa cccaattcag tctcttctaa gcaaaattgc 1650

 taaagagaga tgaaccacat tataaagtaa tctttggctg taaggcattt 1700

 tcatctttcc ttcgggttgg caaaatattt taaaggtaaa acatgctggt 1750

 gaaccagggg tgttgatggt gataagggag gaatatagaa tgaaagactg 1800

 aatcttcctt tgttgcacaa atagagtttg gaaaaagcct gtgaaaggtg 1850

 tcttctttga cttaatgtct ttaaaagtat ccagagatac tacaatatta 1900

 acataagaaa agattatata ttatttctga atcgagatgt ccatagtcaa 1950

 atttgtaaat cttattcttt tgtaatattt atttatattt atttatgaca 2000

 gtgaacattc tgattttaca tgtaaaacaa gaaaagttga agaagatatg 2050

 tgaagaaaaa tgtatttttc ctaaatagaa ataaatgatc ccattttttg 2100

 gt 2102

<210> 499
<211> 381
<212> PRT
<213> Homo sapien

<400> 499
 Met Thr Val Ala Arg Pro Ser Val Pro Ala Ala Leu Pro Leu Leu
   1               5                  10                  15

 Gly Glu Leu Pro Arg Leu Leu Leu Leu Val Leu Leu Cys Leu Pro
                  20                  25                  30

 Ala Val Trp Gly Asp Cys Gly Leu Pro Pro Asp Val Pro Asn Ala
                  35                  40                  45

 Gln Pro Ala Leu Glu Gly Arg Thr Ser Phe Pro Glu Asp Thr Val
                  50                  55                  60

 Ile Thr Tyr Lys Cys Glu Glu Ser Phe Val Lys Ile Pro Gly Glu
                  65                  70                  75

 Lys Asp Ser Val Ile Cys Leu Lys Gly Ser Gln Trp Ser Asp Ile
                  80                  85                  90

 Glu Glu Phe Cys Asn Arg Ser Cys Glu Val Pro Thr Arg Leu Asn
                  95                 100                 105

 Ser Ala Ser Leu Lys Gln Pro Tyr Ile Thr Gln Asn Tyr Phe Pro
                 110                 115                 120

 Val Gly Thr Val Val Glu Tyr Glu Cys Arg Pro Gly Tyr Arg Arg
                 125                 130                 135

 Glu Pro Ser Leu Ser Pro Lys Leu Thr Cys Leu Gln Asn Leu Lys
                 140                 145                 150

 Trp Ser Thr Ala Val Glu Phe Cys Lys Lys Lys Ser Cys Pro Asn
                 155                 160                 165

 Pro Gly Glu Ile Arg Asn Gly Gln Ile Asp Val Pro Gly Gly Ile
                 170                 175                 180

 Leu Phe Gly Ala Thr Ile Ser Phe Ser Cys Asn Thr Gly Tyr Lys
                 185                 190                 195

 Leu Phe Gly Ser Thr Ser Ser Phe Cys Leu Ile Ser Gly Ser Ser
                 200                 205                 210

 Val Gln Trp Ser Asp Pro Leu Pro Glu Cys Arg Glu Ile Tyr Cys
                 215                 220                 225

 Pro Ala Pro Pro Gln Ile Asp Asn Gly Ile Ile Gln Gly Glu Arg
                 230                 235                 240

 Asp His Tyr Gly Tyr Arg Gln Ser Val Thr Tyr Ala Cys Asn Lys
                 245                 250                 255

 Gly Phe Thr Met Ile Gly Glu His Ser Ile Tyr Cys Thr Val Asn
                 260                 265                 270

 Asn Asp Glu Gly Glu Trp Ser Gly Pro Pro Pro Glu Cys Arg Gly
                 275                 280                 285

 Lys Ser Leu Thr Ser Lys Val Pro Pro Thr Val Gln Lys Pro Thr
                 290                 295                 300

 Thr Val Asn Val Pro Thr Thr Glu Val Ser Pro Thr Ser Gln Lys
                 305                 310                 315

 Thr Thr Thr Lys Thr Thr Thr Pro Asn Ala Gln Ala Thr Arg Ser
                 320                 325                 330

 Thr Pro Val Ser Arg Thr Thr Lys His Phe His Glu Thr Thr Pro
                 335                 340                 345

 Asn Lys Gly Ser Gly Thr Thr Ser Gly Thr Thr Arg Leu Leu Ser
                 350                 355                 360

 Gly His Thr Cys Phe Thr Leu Thr Gly Leu Leu Gly Thr Leu Val
                 365                 370                 375

 Thr Met Gly Leu Leu Thr
                 380

<210> 500
<211> 3744
<212> DNA
<213> Homo sapien

<400> 500
 ccacgcgtcc ggtggcggtc gagcgtggcg taggcgaatc ctcggcacta 50

 agcatatgga cctcgcggcg gcagcggagc cgggcgccgg cagccagcac 100

 ctggaggtcc gcgacgaggt ggccgagaag tgccagaaac tgttcctgga 150

 cttcttggag gagtttcaga gcagcgatgg agaaattaaa tacttgcaat 200

 tagcagagga actgattcgt cctgagagaa acacattggt tgtgagtttt 250

 gtggacctgg aacaatttaa ccagcaactt tccaccacca ttcaagagga 300

 gttctataga gtttaccctt acctgtgtcg ggccttgaaa acattcgtca 350

 aagaccgtaa agagatccct cttgccaagg atttttatgt tgcattccaa 400

 gacctgccta ccagacacaa gattcgagag ctcacctcat ccagaattgg 450

 tttgctcact cgcatcagtg ggcaggtggt gcggactcac ccagttcacc 500

 cagagcttgt gagcggaact tttctgtgct tggactgtca gacagtgatc 550

 agggatgtag aacagcagtt caaatacaca cagccaaaca tctgccgaaa 600

 tccagtttgt gccaacagga ggagattctt actggataca aataaatcaa 650

 gatttgttga ttttcaaaag gttcgtattc aagagaccca agctgagctt 700

 cctcgaggga gtatcccccg cagtttagaa gtaattttaa gggctgaagc 750

 tgtggaatca gctcaagctg gtgacaagtg tgactttaca gggacactga 800

 ttgttgtgcc tgacgtctcc aagcttagca caccaggagc acgtgcagaa 850

 actaattccc gtgtcagtgg tgttgatgga tatgagacag aaggcattcg 900

 aggactccgg gcccttggtg ttagggacct ttcttatagg ctggtctttc 950

 ttgcctgctg tgttgcgcca accaacccaa ggtttggggg gaaagagctc 1000

 agagatgagg aacagacagc tgagagcatt aagaaccaaa tgactgtgaa 1050

 agaatgggag aaagtgtttg agatgagtca agataaaaat ctataccaca 1100

 atctttgtac cagcctgttc cctactatac atggcaatga tgaagtaaaa 1150

 cggggtgtcc tgctgatgct ctttggtggc gttccaaaga caacaggaga 1200

 agggacctct cttcgagggg acataaatgt ttgcattgtt ggtgacccaa 1250

 gtacagctaa gagccaattt ctcaagcacg tggaggagtt cagccccaga 1300

 gctgtctaca ccagtggtaa agcgtccagt gctgctggct taacagcagc 1350

 tgttgtgaga gatgaagaat ctcatgagtt tgtcattgag gctggagctt 1400

 tgatgttggc tgataatggt gtgtgttgta ttgatgaatt tgataagatg 1450

 gacgtgcggg atcaagttgc tattcatgaa gctatggaac agcagaccat 1500

 atccatcact aaagcaggag tgaaggctac tctgaacgcc cggacgtcca 1550

 ttttggcagc agcaaaccca atcagtggac actatgacag atcaaaatca 1600

 ttgaaacaga atataaattt gtcagctccc atcatgtccc gattcgatct 1650

 cttctttatc cttgtggatg aatgtaatga ggttacagat tatgccattg 1700

 ccaggcgcat agtagatttg cattcaagaa ttgaggaatc aattgatcgt 1750

 gtctattccc tcgatgatat cagaagatat cttctctttg caagacagtt 1800

 taaacccaag atttccaaag agtcagagga cttcattgtg gagcaatata 1850

 aacatctccg ccagagagat ggttctggag tgaccaagtc ttcatggagg 1900

 attacagtgc gacagcttga gagcatgatt cgtctctctg aagctatggc 1950

 tcggatgcac tgctgtgatg aggtccaacc taaacatgtg aaggaagctt 2000

 tccggttact gaataaatca atcatccgtg tggaaacacc tgatgtcaat 2050

 ctagatcaag aggaagagat ccagatggag gtagatgagg gtgccggtgg 2100

 catcaatggt catgctgaca gccctgctcc tgtgaacggg atcaatggct 2150

 acaatgaaga cataaatcaa gagtctgctc ccaaagcctc cttaaggctg 2200

 ggcttctctg agtactgccg aatctctaac cttattgtgc ttcacctcag 2250

 aaaggtggaa gaagaagagg acgagtcagc attaaagagg agcgagcttg 2300

 ttaactggta cttgaaggaa atcgaatcag agatagactc tgaagaagaa 2350

 cttataaata aaaaaagaat catagagaaa gttattcatc gactcacaca 2400

 ctatgatcat gttctaattg agctcaccca ggctggattg aaaggctcca 2450

 cagagggaag tgagagctat gaagaagatc cctacttggt agttaaccct 2500

 aactacttgc tcgaagattg agatagtgaa agtaactgac cagagctgag 2550

 gaactgtggc acagcacctc gtggcctgga gcctggctgg agctctgcta 2600

 gggacagaag tgtttctgga agtgatgctt ccaggatttg ttttcagaaa 2650

 caagaattga gttgatggtc ctatgtgtca cattcatcac aggtttcata 2700

 ccaacacagg cttcagcact tcctttggtg tgtttcctgt cccagtgaag 2750

 ttggaaccaa ataatgtgta gtctctataa ccaatacctt tgttttcatg 2800

 tgtaagaaaa ggcccattac ttttaaggta tgtgctgtcc tattgagcaa 2850

 ataacttttt ttcaattgcc agctactgct tttattcatc aaaataaaat 2900

 aacttgttct gaagttgtct attggatttc tttctactgt accctgatta 2950

 ttacttccat ctacttctga atgtgagact ttcccttttt gcttaacctg 3000

 gagtgaagag gtagaactgt ggtattatgg atgaggtttc tatgagaagg 3050

 agtcattaga gaactcatat gaaagctaga ggccttagag atgactttcc 3100

 aaggttaatt ccagtttttt ttttttttaa gtttataaaa gtttattata 3150

 cttttttaaa attactcttt agtaatttat tttacttctg tgtcctaagg 3200

 gtaatttctc aggattgttt tcaaattgct tttttagggg aaataggtca 3250

 tttgctatat tacaagcaat ccccaaattt tatggtcttc caggaaaagt 3300

 tattaccgtt tatgatacta acagttcctg agacttagct atgatcagta 3350

 tgttcatgag gtggagcagt tcctgtgttg cagcttttaa caacagatgg 3400

 cattcattaa atcacaaagt atgttaaagg tcacaaaagc aaaataactg 3450

 tctgaggcta aggcccacgt gggacagtct aatacccatg agtactcaac 3500

 ttgccttgat gtctgagctt tccagtgcaa tgtgaatttg agcagccaga 3550

 aatctattag tagaaagcaa gacagattaa tataggttaa aacaatgatt 3600

 taaatatgtt tctcccaata attatctctt tccctggaat caacttgtat 3650

 gaaaccttgt caaaatgtac tccacaagta tgtacaatta agtattttaa 3700

 aaataaatgg caaacattaa aaaaaaaaaa aaaaaaaaaa aaaa 3744

<210> 501
<211> 821
<212> PRT
<213> Homo sapien

<400> 501
 Met Asp Leu Ala Ala Ala Ala Glu Pro Gly Ala Gly Ser Gln His
   1               5                  10                  15

 Leu Glu Val Arg Asp Glu Val Ala Glu Lys Cys Gln Lys Leu Phe
                  20                  25                  30

 Leu Asp Phe Leu Glu Glu Phe Gln Ser Ser Asp Gly Glu Ile Lys
                  35                  40                  45

 Tyr Leu Gln Leu Ala Glu Glu Leu Ile Arg Pro Glu Arg Asn Thr
                  50                  55                  60

 Leu Val Val Ser Phe Val Asp Leu Glu Gln Phe Asn Gln Gln Leu
                  65                  70                  75

 Ser Thr Thr Ile Gln Glu Glu Phe Tyr Arg Val Tyr Pro Tyr Leu
                  80                  85                  90

 Cys Arg Ala Leu Lys Thr Phe Val Lys Asp Arg Lys Glu Ile Pro
                  95                 100                 105

 Leu Ala Lys Asp Phe Tyr Val Ala Phe Gln Asp Leu Pro Thr Arg
                 110                 115                 120

 His Lys Ile Arg Glu Leu Thr Ser Ser Arg Ile Gly Leu Leu Thr
                 125                 130                 135

 Arg Ile Ser Gly Gln Val Val Arg Thr His Pro Val His Pro Glu
                 140                 145                 150

 Leu Val Ser Gly Thr Phe Leu Cys Leu Asp Cys Gln Thr Val Ile
                 155                 160                 165

 Arg Asp Val Glu Gln Gln Phe Lys Tyr Thr Gln Pro Asn Ile Cys
                 170                 175                 180

 Arg Asn Pro Val Cys Ala Asn Arg Arg Arg Phe Leu Leu Asp Thr
                 185                 190                 195

 Asn Lys Ser Arg Phe Val Asp Phe Gln Lys Val Arg Ile Gln Glu
                 200                 205                 210

 Thr Gln Ala Glu Leu Pro Arg Gly Ser Ile Pro Arg Ser Leu Glu
                 215                 220                 225

 Val Ile Leu Arg Ala Glu Ala Val Glu Ser Ala Gln Ala Gly Asp
                 230                 235                 240

 Lys Cys Asp Phe Thr Gly Thr Leu Ile Val Val Pro Asp Val Ser
                 245                 250                 255

 Lys Leu Ser Thr Pro Gly Ala Arg Ala Glu Thr Asn Ser Arg Val
                 260                 265                 270

 Ser Gly Val Asp Gly Tyr Glu Thr Glu Gly Ile Arg Gly Leu Arg
                 275                 280                 285

 Ala Leu Gly Val Arg Asp Leu Ser Tyr Arg Leu Val Phe Leu Ala
                 290                 295                 300

 Cys Cys Val Ala Pro Thr Asn Pro Arg Phe Gly Gly Lys Glu Leu
                 305                 310                 315

 Arg Asp Glu Glu Gln Thr Ala Glu Ser Ile Lys Asn Gln Met Thr
                 320                 325                 330

 Val Lys Glu Trp Glu Lys Val Phe Glu Met Ser Gln Asp Lys Asn
                 335                 340                 345

 Leu Tyr His Asn Leu Cys Thr Ser Leu Phe Pro Thr Ile His Gly
                 350                 355                 360

 Asn Asp Glu Val Lys Arg Gly Val Leu Leu Met Leu Phe Gly Gly
                 365                 370                 375

 Val Pro Lys Thr Thr Gly Glu Gly Thr Ser Leu Arg Gly Asp Ile
                 380                 385                 390

 Asn Val Cys Ile Val Gly Asp Pro Ser Thr Ala Lys Ser Gln Phe
                 395                 400                 405

 Leu Lys His Val Glu Glu Phe Ser Pro Arg Ala Val Tyr Thr Ser
                 410                 415                 420

 Gly Lys Ala Ser Ser Ala Ala Gly Leu Thr Ala Ala Val Val Arg
                 425                 430                 435

 Asp Glu Glu Ser His Glu Phe Val Ile Glu Ala Gly Ala Leu Met
                 440                 445                 450

 Leu Ala Asp Asn Gly Val Cys Cys Ile Asp Glu Phe Asp Lys Met
                 455                 460                 465

 Asp Val Arg Asp Gln Val Ala Ile His Glu Ala Met Glu Gln Gln
                 470                 475                 480

 Thr Ile Ser Ile Thr Lys Ala Gly Val Lys Ala Thr Leu Asn Ala
                 485                 490                 495

 Arg Thr Ser Ile Leu Ala Ala Ala Asn Pro Ile Ser Gly His Tyr
                 500                 505                 510

 Asp Arg Ser Lys Ser Leu Lys Gln Asn Ile Asn Leu Ser Ala Pro
                 515                 520                 525

 Ile Met Ser Arg Phe Asp Leu Phe Phe Ile Leu Val Asp Glu Cys
                 530                 535                 540

 Asn Glu Val Thr Asp Tyr Ala Ile Ala Arg Arg Ile Val Asp Leu
                 545                 550                 555

 His Ser Arg Ile Glu Glu Ser Ile Asp Arg Val Tyr Ser Leu Asp
                 560                 565                 570

 Asp Ile Arg Arg Tyr Leu Leu Phe Ala Arg Gln Phe Lys Pro Lys
                 575                 580                 585

 Ile Ser Lys Glu Ser Glu Asp Phe Ile Val Glu Gln Tyr Lys His
                 590                 595                 600

 Leu Arg Gln Arg Asp Gly Ser Gly Val Thr Lys Ser Ser Trp Arg
                 605                 610                 615

 Ile Thr Val Arg Gln Leu Glu Ser Met Ile Arg Leu Ser Glu Ala
                 620                 625                 630

 Met Ala Arg Met His Cys Cys Asp Glu Val Gln Pro Lys His Val
                 635                 640                 645

 Lys Glu Ala Phe Arg Leu Leu Asn Lys Ser Ile Ile Arg Val Glu
                 650                 655                 660

 Thr Pro Asp Val Asn Leu Asp Gln Glu Glu Glu Ile Gln Met Glu
                 665                 670                 675

 Val Asp Glu Gly Ala Gly Gly Ile Asn Gly His Ala Asp Ser Pro
                 680                 685                 690

 Ala Pro Val Asn Gly Ile Asn Gly Tyr Asn Glu Asp Ile Asn Gln
                 695                 700                 705

 Glu Ser Ala Pro Lys Ala Ser Leu Arg Leu Gly Phe Ser Glu Tyr
                 710                 715                 720

 Cys Arg Ile Ser Asn Leu Ile Val Leu His Leu Arg Lys Val Glu
                 725                 730                 735

 Glu Glu Glu Asp Glu Ser Ala Leu Lys Arg Ser Glu Leu Val Asn
                 740                 745                 750

 Trp Tyr Leu Lys Glu Ile Glu Ser Glu Ile Asp Ser Glu Glu Glu
                 755                 760                 765

 Leu Ile Asn Lys Lys Arg Ile Ile Glu Lys Val Ile His Arg Leu
                 770                 775                 780

 Thr His Tyr Asp His Val Leu Ile Glu Leu Thr Gln Ala Gly Leu
                 785                 790                 795

 Lys Gly Ser Thr Glu Gly Ser Glu Ser Tyr Glu Glu Asp Pro Tyr
                 800                 805                 810

 Leu Val Val Asn Pro Asn Tyr Leu Leu Glu Asp
                 815                 820

<210> 502
<211> 1627
<212> DNA
<213> Homo sapien

<400> 502
 gcccccacca tcaaggggaa gaaagtgctc ttcggattcc ggttcgccct 50

 ggcctcccgc agccgccgcg ggaccggccc ccagcacacc cccggggcgc 100

 cgggcgcggg gcagccgccc ggacgcgcgc gggcctcagg cgccgccggg 150

 accccagccc cccaaacttt ggcaagttgc gggcgccgag cgcacccgga 200

 ggcgcggggc gcggccgcag gcggagccgc cccctgacgc cgggccgccc 250

 cctcccggcc ccggccgccc cgccggctcc gcggaaagtt tgcggccgcc 300

 cctgcgccgc acccggggcc tgggtgagac tgcggcggcg gcagggcgcg 350

 gacggccata tttgccggcg cggcccgagc cgccgacaac aaaaagtgcg 400

 cgggcgctcg gcgggcgctc ggacgggcgc ggggctgcag cgctaccgcc 450

 cggcctcgcc gccgccgccg ccgccctcgc ggcctggccc cgccgcgccc 500

 ggcgcgcccg ccgcccgggg ggatgtctta caaaccgaac ttggccgcgc 550

 acatgcccgc cgccgccctc aacgccgctg ggagtgtcca ctcgccttcc 600

 accagcatgg caacgtcttc acagtaccgc cagctgctca gtgactacgg 650

 gccaccgtcc ctaggctaca cccagggaac tgggaacagc caggtgcccc 700

 aaagcaaata cgcggagctg ctggccatca ttgaagagct ggggaaggag 750

 atcagaccca cgtacgcagg gagcaagagt gccatggaga ggctgaagcg 800

 cggcatcatt cacgctagag gactggttcg ggagtgcttg gcagaaacgg 850

 aacggaatgc cagatcctag ctgccttgtt ggttttgaag gatttccatc 900

 tttttacaag atgagaagtt acagttcatc tcccctgttc agatgaaacc 950

 cttgttttca aaatggttac agtttcgttt ttcctcccat ggttcacttg 1000

 gctctgaacc tacagtctca aagattgaga aaagattttg cagttaatta 1050

 ggatttgcat tttaagtagt taggaactgc ccaggttttt tttgtttttt 1100

 aagcattgat ttaaaagatg cacggaaagt tatcttacag caaactgtag 1150

 tttgcctcca agacaccatt gtctcccttt aatcttctct tttgtataca 1200

 tttgttaccc atggtgttct ttgttccttt tcataagcta ataccactgt 1250

 agggattttg ttttgaacgc atattgacag cacgctttac ttagtagccg 1300

 gttcccattt gccatacaat gtaggttctg cttaatgtaa cttctttttt 1350

 gcttaagcat ttgcatgact attagtgctt caaagtcaat ttttaaaaat 1400

 gcacaagtta taaatacaga agaaagagca acccaccaaa cctaacaagg 1450

 acccccgaac actttcatac taagactgta agtagatctc agttctgcgt 1500

 ttattgtaag ttgataaaaa catctggaag aaaatgacta aaactgtttg 1550

 catctttgta tgtatttatt acttgatgta ataaagctta ttttcattaa 1600

 caatttgtat taaaaaaaaa aaaaaaa 1627

<210> 503
<211> 115
<212> PRT
<213> Homo sapien

<400> 503
 Met Ser Tyr Lys Pro Asn Leu Ala Ala His Met Pro Ala Ala Ala
   1               5                  10                  15

 Leu Asn Ala Ala Gly Ser Val His Ser Pro Ser Thr Ser Met Ala
                  20                  25                  30

 Thr Ser Ser Gln Tyr Arg Gln Leu Leu Ser Asp Tyr Gly Pro Pro
                  35                  40                  45

 Ser Leu Gly Tyr Thr Gln Gly Thr Gly Asn Ser Gln Val Pro Gln
                  50                  55                  60

 Ser Lys Tyr Ala Glu Leu Leu Ala Ile Ile Glu Glu Leu Gly Lys
                  65                  70                  75

 Glu Ile Arg Pro Thr Tyr Ala Gly Ser Lys Ser Ala Met Glu Arg
                  80                  85                  90

 Leu Lys Arg Gly Ile Ile His Ala Arg Gly Leu Val Arg Glu Cys
                  95                 100                 105

 Leu Ala Glu Thr Glu Arg Asn Ala Arg Ser
                 110                 115

<210> 504
<211> 4180
<212> DNA
<213> Homo sapien

<400> 504
 gcggggaagc agcagcggcc aggatgaatc ccaggtgctc tggagctgga 50

 tggtgaaggt cggcactctt caccctcccg agccctgccc gtctcggccc 100

 catgccccca ccagtcagcc ccgggccaca ggcagtgagc aggcacctgg 150

 gagccgaggc cctgtgacca ggccaaggag acgggcgctc cagggtccca 200

 gccacctgtc ccccccatgg agctgaggcc ctggttgcta tgggtggtag 250

 cagcaacagg aaccttggtc ctgctagcag ctgatgctca gggccagaag 300

 gtcttcacca acacgtgggc tgtgcgcatc cctggaggcc cagcggtggc 350

 caacagtgtg gcacggaagc atgggttcct caacctgggc cagatcttcg 400

 gggactatta ccacttctgg catcgaggag tgacgaagcg gtccctgtcg 450

 cctcaccgcc cgcggcacag ccggctgcag agggagcctc aagtacagtg 500

 gctggaacag caggtggcaa agcgacggac taaacgggac gtgtaccagg 550

 agcccacaga ccccaagttt cctcagcagt ggtacctgtc tggtgtcact 600

 cagcgggacc tgaatgtgaa ggcggcctgg gcgcagggct acacagggca 650

 cggcattgtg gtctccattc tggacgatgg catcgagaag aaccacccgg 700

 acttggcagg caattatgat cctggggcca gttttgatgt caatgaccag 750

 gaccctgacc cccagcctcg gtacacacag atgaatgaca acaggcacgg 800

 cacacggtgt gcgggggaag tggctgcggt ggccaacaac ggtgtctgtg 850

 gtgtaggtgt ggcctacaac gcccgcattg gaggggtgcg catgctggat 900

 ggcgaggtga cagatgcagt ggaggcacgc tcgctgggcc tgaaccccaa 950

 ccacatccac atctacagtg ccagctgggg ccccgaggat gacggcaaga 1000

 cagtggatgg gccagcccgc ctcgccgagg aggccttctt ccgtggggtt 1050

 agccagggcc gaggggggct gggctccatc tttgtctggg cctcggggaa 1100

 cgggggccgg gaacatgaca gctgcaactg cgacggctac accaacagta 1150

 tctacacgct gtccatcagc agcgccacgc agtttggcaa cgtgccgtgg 1200

 tacagcgagg cctgctcgtc cacactggcc acgacctaca gcagtggcaa 1250

 ccagaatgag aagcagatcg tgacgactga cttgcggcag aagtgcacgg 1300

 agtctcacac gggcacctca gcctctgccc ccttagcagc cggcatcatt 1350

 gctctcaccc tggaggccaa taagaacctc acatggcggg acatgcaaca 1400

 cctggtggta cagacctcga agccagccca cctcaatgcc aacgactggg 1450

 ccaccaatgg tgtgggccgg aaagtgagcc actcatatgg ctacgggctt 1500

 ttggacgcag gcgccatggt ggccctggcc cagaattgga ccacagtggc 1550

 cccccagcgg aagtgcatca tcgacatcct caccgagccc aaagacatcg 1600

 ggaaacggct cgaggtgcgg aagaccgtga ccgcgtgcct gggcgagccc 1650

 aaccacatca ctcggctgga gcacgctcag gcgcggctca ccctgtccta 1700

 taatcgccgt ggcgacctgg ccatccacct ggtcagcccc atgggcaccc 1750

 gctccaccct gctggcagcc aggccacatg actactccgc agatgggttt 1800

 aatgactggg ccttcatgac aactcattcc tgggatgagg atccctctgg 1850

 cgagtgggtc ctagagattg aaaacaccag cgaagccaac aactatggga 1900

 cgctgaccaa gttcaccctc gtactctatg gcaccgcccc tgaggggctg 1950

 cccgtacctc cagaaagcag tggctgcaag accctcacgt ccagtcaggc 2000

 ctgtgtggtg tgcgaggaag gcttctccct gcaccagaag agctgtgtcc 2050

 agcactgccc tccagggttc gccccccaag tcctcgatac gcactatagc 2100

 accgagaatg acgtggagac catccgggcc agcgtctgcg ccccctgcca 2150

 cgcctcatgt gccacatgcc aggggccggc cctgacagac tgcctcagct 2200

 gccccagcca cgcctccttg gaccctgtgg agcagacttg ctcccggcaa 2250

 agccagagca gccgagagtc cccgccacag cagcagccac ctcggctgcc 2300

 cccggaggtg gaggcggggc aacggctgcg ggcagggctg ctgccctcac 2350

 acctgcctga ggtggtggcc ggcctcagct gcgccttcat cgtgctggtc 2400

 ttcgtcactg tcttcctggt cctgcagctg cgctctggct ttagttttcg 2450

 gggggtgaag gtgtacacca tggaccgtgg cctcatctcc tacaaggggc 2500

 tgccccctga agcctggcag gaggagtgcc cgtctgactc agaagaggac 2550

 gagggccggg gcgagaggac cgcctttatc aaagaccaga gcgccctctg 2600

 atgagcccac tgcccacccc ctcaagccaa tcccctcctt gggcactttt 2650

 taattcacca aagtattttt ttatcttggg actgggtttg gaccccagct 2700

 gggaggcaag aggggtggag actgcttccc atcctaccct cgggcccacc 2750

 tggccacctg aggtgggccc aggaccagct ggggcgtggg gagggccgta 2800

 ccccaccctc agcacccctt ccatgtggag aaaggagtga aacctttagg 2850

 gcagcttgcc ccggccccgg ccccagccag agttcctgcg gagtgaagag 2900

 gggcagccct tgcttgttgg gattcctgac ccaggccgca gctcttgccc 2950

 ttccctgtcc ctctaaagca ataatggtcc catccaggca gtcgggggct 3000

 ggcctaggag atatctgagg gaggaggcca cctctccaag ggcttctgca 3050

 ccctccaccc tgtcccccag ctctggtgag tcttggcggc agcagccatc 3100

 ataggaaggg accaaggcaa ggcaggtgcc tccaggtgtg cacgtggcat 3150

 gtggcctgtg gcctgtgtcc catgacccac ccctgtgctc cgtgcctcca 3200

 ccaccactgg ccaccaggct ggcgcagcca aggccgaagc tctggctgaa 3250

 ccctgtgctg gtgtcctgac caccctcccc tctcttgcac ccgcctctcc 3300

 cgtcagggcc caagtccctg ttttctgagc ccgggctgcc tgggctgttg 3350

 gcactcacag acctggagcc cctgggtggg tggtggggag gggcgctggc 3400

 ccagccggcc tctctggcct cccacccgat gctgctttcc cctgtgggga 3450

 tctcaggggc tgtttgagga tatattttca ctttgtgatt atttcacttt 3500

 agatgctgat gatttgtttt tgtattttta atgggggtag cagctggact 3550

 acccacgttc tcacacccac cgtccgccct gctcctccct ggctgccctg 3600

 gccctgaggt gtgggggctg cagcatgttg ctgaggagtg aggaatagtt 3650

 gagccccaag tcctgaagag gcgggccagc caggcgggct caaggaaagg 3700

 gggtcccagt gggaggggca ggctgacatc tgtgtttcaa gtggggctcg 3750

 ccatgccggg ggttcatagg tcactggctc tccaagtgcc agaggtgggc 3800

 aggtggtggc actgagcccc cccaacactg tgccctggtg gagaaagcac 3850

 tgacctgtca tgcccccctc aaacctcctc ttctgacgtg ccttttgcac 3900

 ccctcccatt aggacaatca gtcccctccc atctgggagt ccccttttct 3950

 tttctaccct agccattcct ggtacccagc catctgccca ggggtgcccc 4000

 ctcctctccc atccccctgc cctcgtggcc agcccggctg gttttgtaag 4050

 atgctgggtt ggtgcacagt gatttttttc ttgtaattta aacaggccca 4100

 gcattgctgg ttctatttaa tggacatgag ataatgttag aggttttaaa 4150

 gtgattaaac gtgcagacta tgcaaaccag 4180

<210> 505
<211> 794
<212> PRT
<213> Homo sapien

<400> 505
 Met Glu Leu Arg Pro Trp Leu Leu Trp Val Val Ala Ala Thr Gly
   1               5                  10                  15

 Thr Leu Val Leu Leu Ala Ala Asp Ala Gln Gly Gln Lys Val Phe
                  20                  25                  30

 Thr Asn Thr Trp Ala Val Arg Ile Pro Gly Gly Pro Ala Val Ala
                  35                  40                  45

 Asn Ser Val Ala Arg Lys His Gly Phe Leu Asn Leu Gly Gln Ile
                  50                  55                  60

 Phe Gly Asp Tyr Tyr His Phe Trp His Arg Gly Val Thr Lys Arg
                  65                  70                  75

 Ser Leu Ser Pro His Arg Pro Arg His Ser Arg Leu Gln Arg Glu
                  80                  85                  90

 Pro Gln Val Gln Trp Leu Glu Gln Gln Val Ala Lys Arg Arg Thr
                  95                 100                 105

 Lys Arg Asp Val Tyr Gln Glu Pro Thr Asp Pro Lys Phe Pro Gln
                 110                 115                 120

 Gln Trp Tyr Leu Ser Gly Val Thr Gln Arg Asp Leu Asn Val Lys
                 125                 130                 135

 Ala Ala Trp Ala Gln Gly Tyr Thr Gly His Gly Ile Val Val Ser
                 140                 145                 150

 Ile Leu Asp Asp Gly Ile Glu Lys Asn His Pro Asp Leu Ala Gly
                 155                 160                 165

 Asn Tyr Asp Pro Gly Ala Ser Phe Asp Val Asn Asp Gln Asp Pro
                 170                 175                 180

 Asp Pro Gln Pro Arg Tyr Thr Gln Met Asn Asp Asn Arg His Gly
                 185                 190                 195

 Thr Arg Cys Ala Gly Glu Val Ala Ala Val Ala Asn Asn Gly Val
                 200                 205                 210

 Cys Gly Val Gly Val Ala Tyr Asn Ala Arg Ile Gly Gly Val Arg
                 215                 220                 225

 Met Leu Asp Gly Glu Val Thr Asp Ala Val Glu Ala Arg Ser Leu
                 230                 235                 240

 Gly Leu Asn Pro Asn His Ile His Ile Tyr Ser Ala Ser Trp Gly
                 245                 250                 255

 Pro Glu Asp Asp Gly Lys Thr Val Asp Gly Pro Ala Arg Leu Ala
                 260                 265                 270

 Glu Glu Ala Phe Phe Arg Gly Val Ser Gln Gly Arg Gly Gly Leu
                 275                 280                 285

 Gly Ser Ile Phe Val Trp Ala Ser Gly Asn Gly Gly Arg Glu His
                 290                 295                 300

 Asp Ser Cys Asn Cys Asp Gly Tyr Thr Asn Ser Ile Tyr Thr Leu
                 305                 310                 315

 Ser Ile Ser Ser Ala Thr Gln Phe Gly Asn Val Pro Trp Tyr Ser
                 320                 325                 330

 Glu Ala Cys Ser Ser Thr Leu Ala Thr Thr Tyr Ser Ser Gly Asn
                 335                 340                 345

 Gln Asn Glu Lys Gln Ile Val Thr Thr Asp Leu Arg Gln Lys Cys
                 350                 355                 360

 Thr Glu Ser His Thr Gly Thr Ser Ala Ser Ala Pro Leu Ala Ala
                 365                 370                 375

 Gly Ile Ile Ala Leu Thr Leu Glu Ala Asn Lys Asn Leu Thr Trp
                 380                 385                 390

 Arg Asp Met Gln His Leu Val Val Gln Thr Ser Lys Pro Ala His
                 395                 400                 405

 Leu Asn Ala Asn Asp Trp Ala Thr Asn Gly Val Gly Arg Lys Val
                 410                 415                 420

 Ser His Ser Tyr Gly Tyr Gly Leu Leu Asp Ala Gly Ala Met Val
                 425                 430                 435

 Ala Leu Ala Gln Asn Trp Thr Thr Val Ala Pro Gln Arg Lys Cys
                 440                 445                 450

 Ile Ile Asp Ile Leu Thr Glu Pro Lys Asp Ile Gly Lys Arg Leu
                 455                 460                 465

 Glu Val Arg Lys Thr Val Thr Ala Cys Leu Gly Glu Pro Asn His
                 470                 475                 480

 Ile Thr Arg Leu Glu His Ala Gln Ala Arg Leu Thr Leu Ser Tyr
                 485                 490                 495

 Asn Arg Arg Gly Asp Leu Ala Ile His Leu Val Ser Pro Met Gly
                 500                 505                 510

 Thr Arg Ser Thr Leu Leu Ala Ala Arg Pro His Asp Tyr Ser Ala
                 515                 520                 525

 Asp Gly Phe Asn Asp Trp Ala Phe Met Thr Thr His Ser Trp Asp
                 530                 535                 540

 Glu Asp Pro Ser Gly Glu Trp Val Leu Glu Ile Glu Asn Thr Ser
                 545                 550                 555

 Glu Ala Asn Asn Tyr Gly Thr Leu Thr Lys Phe Thr Leu Val Leu
                 560                 565                 570

 Tyr Gly Thr Ala Pro Glu Gly Leu Pro Val Pro Pro Glu Ser Ser
                 575                 580                 585

 Gly Cys Lys Thr Leu Thr Ser Ser Gln Ala Cys Val Val Cys Glu
                 590                 595                 600

 Glu Gly Phe Ser Leu His Gln Lys Ser Cys Val Gln His Cys Pro
                 605                 610                 615

 Pro Gly Phe Ala Pro Gln Val Leu Asp Thr His Tyr Ser Thr Glu
                 620                 625                 630

 Asn Asp Val Glu Thr Ile Arg Ala Ser Val Cys Ala Pro Cys His
                 635                 640                 645

 Ala Ser Cys Ala Thr Cys Gln Gly Pro Ala Leu Thr Asp Cys Leu
                 650                 655                 660

 Ser Cys Pro Ser His Ala Ser Leu Asp Pro Val Glu Gln Thr Cys
                 665                 670                 675

 Ser Arg Gln Ser Gln Ser Ser Arg Glu Ser Pro Pro Gln Gln Gln
                 680                 685                 690

 Pro Pro Arg Leu Pro Pro Glu Val Glu Ala Gly Gln Arg Leu Arg
                 695                 700                 705

 Ala Gly Leu Leu Pro Ser His Leu Pro Glu Val Val Ala Gly Leu
                 710                 715                 720

 Ser Cys Ala Phe Ile Val Leu Val Phe Val Thr Val Phe Leu Val
                 725                 730                 735

 Leu Gln Leu Arg Ser Gly Phe Ser Phe Arg Gly Val Lys Val Tyr
                 740                 745                 750

 Thr Met Asp Arg Gly Leu Ile Ser Tyr Lys Gly Leu Pro Pro Glu
                 755                 760                 765

 Ala Trp Gln Glu Glu Cys Pro Ser Asp Ser Glu Glu Asp Glu Gly
                 770                 775                 780

 Arg Gly Glu Arg Thr Ala Phe Ile Lys Asp Gln Ser Ala Leu
                 785                 790

<210> 506
<211> 1935
<212> DNA
<213> Homo sapien

<400> 506
 ctggtcccga gcacgagctg tgaggggatt cacttgtgtg cggaactcct 50

 cggaaccatg gcgtcccttt cccttgcacc tgttaacatc tttaaggcag 100

 gagctgatga agagagagca gagacagctc gtctgacttc ttttattggt 150

 gccatcgcca ttggagactt ggtaaagagc accttgggac ccaaaggcat 200

 ggacaaaatt cttctaagca gtggacgaga tgcctctctt atggtaacca 250

 atgatggtgc cactattcta aaaaacattg gtgttgacaa tccagcagct 300

 aaagttttag ttgatatgtc aagggttcaa gatgatgaag ttggtgatgg 350

 cactacctct gttaccgttt tagcagcaga attattaagg gaagcagaat 400

 ctttaattgc aaaaaagatt catccacaga ccatcatagc gggttggaga 450

 gaagccacga aggctgcaag agaggcgctg ttgagttctg cagttgatca 500

 tggttccgat gaagttaaat tccgtcaaga tttaatgaat attgcgggca 550

 caacattatc ctcaaaactt cttactcatc acaaagacca ctttacaaag 600

 ttagctgtag aagcagttct cagactgaaa ggctctggca acctggaggc 650

 aattcatatt atcaagaagc taggaggaag tttggcagat tcctatttag 700

 atgaaggctt cctgttggat aaaaaaattg gagtaaatca accaaaacga 750

 attgaaaatg ctaaaattct tattgcaaat actggtatgg atacagacaa 800

 aataaagata tttggttccc gggtaagagt tgactctaca gcaaaggttg 850

 cagaaataga acatgcggaa aaggaaaaaa tgaaggagaa agttgaacgt 900

 attcttaagc atggaataaa ttgctttatt aacaggcaat taatttataa 950

 ttatcctgaa cagctctttg gtgctgctgg tgtcatggct attgagcatg 1000

 cagattttgc aggtgtggaa cgcctagctc ttgtcacagg tggtgaaatt 1050

 gcctctacct ttgatcaccc agaactggtg aagcttggaa gttgcaaact 1100

 tatcgaggaa gtcatgattg gagaagacaa actcattcac ttttctgggg 1150

 ttgcccttgg tgaggcttgt accattgttt tgcgtggtgc cactcaacaa 1200

 attttagatg aagcagaaag atcattgcat gatgctcttt gtgttcttgc 1250

 gcaaactgta aaggactcta gaacagttta tggaggaggc tgttctgaga 1300

 tgttgatggc tcatgctgtg acacagcttg ccaatagaac accaggcaaa 1350

 gaagctgttg caatggagtc ttatgctaaa gcactgagaa tgttgccaac 1400

 catcatagct gacaatgcag gctatgacag tgcagacctg gtggcacagc 1450

 tcagggctgc tcacagtgaa ggcaatacca ctgctggatt ggatatgagg 1500

 gaaggcacca ttggagatat ggctatcctg ggtataacag aaagttttca 1550

 agtgaagcga caggttcttc tgagtgcagc tgaagcagca gaggtgattc 1600

 tgcgtgtgga caacatcatc aaagcggcac ccaggaaacg tgtccctgat 1650

 caccacccct gttaagcatt cccacgtgct gtcgatcttt ggaccagttt 1700

 ctagcaaagt tgtgtttgaa agatactcta ttaaagaaga ctgtggaatc 1750

 tgtttatcgg tgcccattat atccttaagt ttggatattt agctgacctt 1800

 cgctttaaca taggtctaat ttatttgccg tgtcattttc catacaaatc 1850

 agttgattta aaggagttca tttcgcatac tgggcattaa aataaaaatt 1900

 tgaacaatga aaggaaaaaa aggagaaaaa aaaaa 1935

<210> 507
<211> 535
<212> PRT
<213> Homo sapien

<400> 507
 Met Ala Ser Leu Ser Leu Ala Pro Val Asn Ile Phe Lys Ala Gly
   1               5                  10                  15

 Ala Asp Glu Glu Arg Ala Glu Thr Ala Arg Leu Thr Ser Phe Ile
                  20                  25                  30

 Gly Ala Ile Ala Ile Gly Asp Leu Val Lys Ser Thr Leu Gly Pro
                  35                  40                  45

 Lys Gly Met Asp Lys Ile Leu Leu Ser Ser Gly Arg Asp Ala Ser
                  50                  55                  60

 Leu Met Val Thr Asn Asp Gly Ala Thr Ile Leu Lys Asn Ile Gly
                  65                  70                  75

 Val Asp Asn Pro Ala Ala Lys Val Leu Val Asp Met Ser Arg Val
                  80                  85                  90

 Gln Asp Asp Glu Val Gly Asp Gly Thr Thr Ser Val Thr Val Leu
                  95                 100                 105

 Ala Ala Glu Leu Leu Arg Glu Ala Glu Ser Leu Ile Ala Lys Lys
                 110                 115                 120

 Ile His Pro Gln Thr Ile Ile Ala Gly Trp Arg Glu Ala Thr Lys
                 125                 130                 135

 Ala Ala Arg Glu Ala Leu Leu Ser Ser Ala Val Asp His Gly Ser
                 140                 145                 150

 Asp Glu Val Lys Phe Arg Gln Asp Leu Met Asn Ile Ala Gly Thr
                 155                 160                 165

 Thr Leu Ser Ser Lys Leu Leu Thr His His Lys Asp His Phe Thr
                 170                 175                 180

 Lys Leu Ala Val Glu Ala Val Leu Arg Leu Lys Gly Ser Gly Asn
                 185                 190                 195

 Leu Glu Ala Ile His Ile Ile Lys Lys Leu Gly Gly Ser Leu Ala
                 200                 205                 210

 Asp Ser Tyr Leu Asp Glu Gly Phe Leu Leu Asp Lys Lys Ile Gly
                 215                 220                 225

 Val Asn Gln Pro Lys Arg Ile Glu Asn Ala Lys Ile Leu Ile Ala
                 230                 235                 240

 Asn Thr Gly Met Asp Thr Asp Lys Ile Lys Ile Phe Gly Ser Arg
                 245                 250                 255

 Val Arg Val Asp Ser Thr Ala Lys Val Ala Glu Ile Glu His Ala
                 260                 265                 270

 Glu Lys Glu Lys Met Lys Glu Lys Val Glu Arg Ile Leu Lys His
                 275                 280                 285

 Gly Ile Asn Cys Phe Ile Asn Arg Gln Leu Ile Tyr Asn Tyr Pro
                 290                 295                 300

 Glu Gln Leu Phe Gly Ala Ala Gly Val Met Ala Ile Glu His Ala
                 305                 310                 315

 Asp Phe Ala Gly Val Glu Arg Leu Ala Leu Val Thr Gly Gly Glu
                 320                 325                 330

 Ile Ala Ser Thr Phe Asp His Pro Glu Leu Val Lys Leu Gly Ser
                 335                 340                 345

 Cys Lys Leu Ile Glu Glu Val Met Ile Gly Glu Asp Lys Leu Ile
                 350                 355                 360

 His Phe Ser Gly Val Ala Leu Gly Glu Ala Cys Thr Ile Val Leu
                 365                 370                 375

 Arg Gly Ala Thr Gln Gln Ile Leu Asp Glu Ala Glu Arg Ser Leu
                 380                 385                 390

 His Asp Ala Leu Cys Val Leu Ala Gln Thr Val Lys Asp Ser Arg
                 395                 400                 405

 Thr Val Tyr Gly Gly Gly Cys Ser Glu Met Leu Met Ala His Ala
                 410                 415                 420

 Val Thr Gln Leu Ala Asn Arg Thr Pro Gly Lys Glu Ala Val Ala
                 425                 430                 435

 Met Glu Ser Tyr Ala Lys Ala Leu Arg Met Leu Pro Thr Ile Ile
                 440                 445                 450

 Ala Asp Asn Ala Gly Tyr Asp Ser Ala Asp Leu Val Ala Gln Leu
                 455                 460                 465

 Arg Ala Ala His Ser Glu Gly Asn Thr Thr Ala Gly Leu Asp Met
                 470                 475                 480

 Arg Glu Gly Thr Ile Gly Asp Met Ala Ile Leu Gly Ile Thr Glu
                 485                 490                 495

 Ser Phe Gln Val Lys Arg Gln Val Leu Leu Ser Ala Ala Glu Ala
                 500                 505                 510

 Ala Glu Val Ile Leu Arg Val Asp Asn Ile Ile Lys Ala Ala Pro
                 515                 520                 525

 Arg Lys Arg Val Pro Asp His His Pro Cys
                 530                 535

<210> 508
<211> 1935
<212> DNA
<213> Homo sapien

<400> 508
 ctggtcccga gcacgagctg tgaggggatt cacttgtgtg cggaactcct 50

 cggaaccatg gcgtcccttt cccttgcacc tgttaacatc tttaaggcag 100

 gagctgatga agagagagca gagacagctc gtctgacttc ttttattggt 150

 gccatcgcca ttggagactt ggtaaagagc accttgggac ccaaaggcat 200

 ggacaaaatt cttctaagca gtggacgaga tgcctctctt atggtaacca 250

 atgatggtgc cactattcta aaaaacattg gtgttgacaa tccagcagct 300

 aaagttttag ttgatatgtc aagggttcaa gatgatgaag ttggtgatgg 350

 cactacctct gttaccgttt tagcagcaga attattaagg gaagcagaat 400

 ctttaattgc aaaaaagatt catccacaga ccatcatagc gggttggaga 450

 gaagccacga aggctgcaag agaggcgctg ttgagttctg cagttgatca 500

 tggttccgat gaagttaaat tccgtcaaga tttaatgaat attgcgggca 550

 caacattatc ctcaaaactt cttactcatc acaaagacca ctttacaaag 600

 ttagctgtag aagcagttct cagactgaaa ggctctggca acctggaggc 650

 aattcatatt atcaagaagc taggaggaag tttggcagat tcctatttag 700

 atgaaggctt cctgttggat aaaaaaattg gagtaaatca accaaaacga 750

 attgaaaatg ctaaaattct tattgcaaat actggtatgg atacagacaa 800

 aataaagata tttggttccc gggtaagagt tgactctaca gcaaaggttg 850

 cagaaataga acatgcggaa aaggaaaaaa tgaaggagaa agttgaacgt 900

 attcttaagc atggaataaa ttgctttatt aacaggcaat taatttataa 950

 ttatcctgaa cagctctttg gtgctgctgg tgtcatggct attgagcatg 1000

 cagattttgc aggtgtggaa cgcctagctc ttgtcacagg tggtgaaatt 1050

 gcctctacct ttgatcaccc agaactggtg aagcttggaa gttgcaaact 1100

 tatcgaggaa gtcatgattg gagaagacaa actcattcac ttttctgggg 1150

 ttgcccttgg tgaggcttgt accattgttt tgcgtggtgc cactcaacaa 1200

 attttagatg aagcagaaag atcattgcat gatgctcttt gtgttcttgc 1250

 gcaaactgta aaggactcta gaacagttta tggaggaggc tgttctgaga 1300

 tgttgatggc tcatgctgtg acacagcttg ccaatagaac accaggcaaa 1350

 gaagctgttg caatggagtc ttatgctaaa gcactgagaa tgttgccaac 1400

 catcatagct gacaatgcag gctatgacag tgcagacctg gtggcacagc 1450

 tcagggctgc tcacagtgaa ggcaatacca ctgctggatt ggatatgagg 1500

 gaaggcacca ttggagatat ggctatcctg ggtataacag aaagttttca 1550

 agtgaagcga caggttcttc tgagtgcagc tgaagcagca gaggtgattc 1600

 tgcgtgtgga caacatcatc aaagcggcac ccaggaaacg tgtccctgat 1650

 caccacccct gttaagcatt cccacgtgct gtcgatcttt ggaccagttt 1700

 ctagcaaagt tgtgtttgaa agatactcta ttaaagaaga ctgtggaatc 1750

 tgtttatcgg tgcccattat atccttaagt ttggatattt agctgacctt 1800

 cgctttaaca taggtctaat ttatttgccg tgtcattttc catacaaatc 1850

 agttgattta aaggagttca tttcgcatac tgggcattaa aataaaaatt 1900

 tgaacaatga aaggaaaaaa aggagaaaaa aaaaa 1935

<210> 509
<211> 535
<212> PRT
<213> Homo sapien

<400> 509
 Met Ala Ser Leu Ser Leu Ala Pro Val Asn Ile Phe Lys Ala Gly
   1               5                  10                  15

 Ala Asp Glu Glu Arg Ala Glu Thr Ala Arg Leu Thr Ser Phe Ile
                  20                  25                  30

 Gly Ala Ile Ala Ile Gly Asp Leu Val Lys Ser Thr Leu Gly Pro
                  35                  40                  45

 Lys Gly Met Asp Lys Ile Leu Leu Ser Ser Gly Arg Asp Ala Ser
                  50                  55                  60

 Leu Met Val Thr Asn Asp Gly Ala Thr Ile Leu Lys Asn Ile Gly
                  65                  70                  75

 Val Asp Asn Pro Ala Ala Lys Val Leu Val Asp Met Ser Arg Val
                  80                  85                  90

 Gln Asp Asp Glu Val Gly Asp Gly Thr Thr Ser Val Thr Val Leu
                  95                 100                 105

 Ala Ala Glu Leu Leu Arg Glu Ala Glu Ser Leu Ile Ala Lys Lys
                 110                 115                 120

 Ile His Pro Gln Thr Ile Ile Ala Gly Trp Arg Glu Ala Thr Lys
                 125                 130                 135

 Ala Ala Arg Glu Ala Leu Leu Ser Ser Ala Val Asp His Gly Ser
                 140                 145                 150

 Asp Glu Val Lys Phe Arg Gln Asp Leu Met Asn Ile Ala Gly Thr
                 155                 160                 165

 Thr Leu Ser Ser Lys Leu Leu Thr His His Lys Asp His Phe Thr
                 170                 175                 180

 Lys Leu Ala Val Glu Ala Val Leu Arg Leu Lys Gly Ser Gly Asn
                 185                 190                 195

 Leu Glu Ala Ile His Ile Ile Lys Lys Leu Gly Gly Ser Leu Ala
                 200                 205                 210

 Asp Ser Tyr Leu Asp Glu Gly Phe Leu Leu Asp Lys Lys Ile Gly
                 215                 220                 225

 Val Asn Gln Pro Lys Arg Ile Glu Asn Ala Lys Ile Leu Ile Ala
                 230                 235                 240

 Asn Thr Gly Met Asp Thr Asp Lys Ile Lys Ile Phe Gly Ser Arg
                 245                 250                 255

 Val Arg Val Asp Ser Thr Ala Lys Val Ala Glu Ile Glu His Ala
                 260                 265                 270

 Glu Lys Glu Lys Met Lys Glu Lys Val Glu Arg Ile Leu Lys His
                 275                 280                 285

 Gly Ile Asn Cys Phe Ile Asn Arg Gln Leu Ile Tyr Asn Tyr Pro
                 290                 295                 300

 Glu Gln Leu Phe Gly Ala Ala Gly Val Met Ala Ile Glu His Ala
                 305                 310                 315

 Asp Phe Ala Gly Val Glu Arg Leu Ala Leu Val Thr Gly Gly Glu
                 320                 325                 330

 Ile Ala Ser Thr Phe Asp His Pro Glu Leu Val Lys Leu Gly Ser
                 335                 340                 345

 Cys Lys Leu Ile Glu Glu Val Met Ile Gly Glu Asp Lys Leu Ile
                 350                 355                 360

 His Phe Ser Gly Val Ala Leu Gly Glu Ala Cys Thr Ile Val Leu
                 365                 370                 375

 Arg Gly Ala Thr Gln Gln Ile Leu Asp Glu Ala Glu Arg Ser Leu
                 380                 385                 390

 His Asp Ala Leu Cys Val Leu Ala Gln Thr Val Lys Asp Ser Arg
                 395                 400                 405

 Thr Val Tyr Gly Gly Gly Cys Ser Glu Met Leu Met Ala His Ala
                 410                 415                 420

 Val Thr Gln Leu Ala Asn Arg Thr Pro Gly Lys Glu Ala Val Ala
                 425                 430                 435

 Met Glu Ser Tyr Ala Lys Ala Leu Arg Met Leu Pro Thr Ile Ile
                 440                 445                 450

 Ala Asp Asn Ala Gly Tyr Asp Ser Ala Asp Leu Val Ala Gln Leu
                 455                 460                 465

 Arg Ala Ala His Ser Glu Gly Asn Thr Thr Ala Gly Leu Asp Met
                 470                 475                 480

 Arg Glu Gly Thr Ile Gly Asp Met Ala Ile Leu Gly Ile Thr Glu
                 485                 490                 495

 Ser Phe Gln Val Lys Arg Gln Val Leu Leu Ser Ala Ala Glu Ala
                 500                 505                 510

 Ala Glu Val Ile Leu Arg Val Asp Asn Ile Ile Lys Ala Ala Pro
                 515                 520                 525

 Arg Lys Arg Val Pro Asp His His Pro Cys
                 530                 535

<210> 510
<211> 3635
<212> DNA
<213> Homo sapien

<400> 510
 tcaacacagg acaatgcaag cccatgagct gttccggtat tttcgaatgc 50

 cagagctggt tgacttccga cagtacgtgc gtactcttcc gaccaacacg 100

 cttatgggct tcggagcttt tgcagcactc accaccttct ggtacgccac 150

 gagacccaaa cccctgaagc cgccatgcga cctctccatg cagtcagtgg 200

 aagtggcggg tagtggtggt gcacgaagat ccgcactact tgacagcgac 250

 gagcccttgg tgtatttcta tgatgatgtc acaacattat acgaaggttt 300

 ccagagggga atacaggtgt caaataatgg cccttgttta ggctctcgga 350

 aaccagacca accctatgaa tggctttcat ataaacaggt tgcagaattg 400

 tcggagtgca taggctcagc actgatccag aagggcttca agactgcccc 450

 agatcagttc attggcatct ttgctcaaaa tagacctgag tgggtgatta 500

 ttgaacaagg atgctttgct tattcgatgg tgatcgttcc actttatgat 550

 acccttggaa atgaagccat cacgtacata gtcaacaaag ctgaactctc 600

 tctggttttt gttgacaagc cagagaaggc caaactctta ttagagggtg 650

 tagaaaataa gttaatacca ggccttaaaa tcatagttgt catggatgcc 700

 tacggcagtg aactggtgga acgaggccag aggtgtgggg tggaagtcac 750

 cagcatgaag gcgatggagg acctgggaag agccaacaga cggaagccca 800

 agcctccagc acctgaagat cttgcagtaa tttgtttcac aagtggaact 850

 acaggcaacc ccaaaggagc aatggtcact caccgaaaca tagtgagcga 900

 ttgttcagct tttgtgaaag caacagagaa tacagtcaat ccttgcccag 950

 atgatacttt gatatctttc ttgcctctcg cccatatgtt tgagagagtt 1000

 gtagagtgtg taatgctgtg tcatggagct aaaatcggat ttttccaagg 1050

 agatatcagg ctgctcatgg atgacctcaa ggtgcttcaa cccactgtct 1100

 tccccgtggt tccaagactg ctgaaccgga tgtttgaccg aattttcgga 1150

 caagcaaaca ccacgctgaa gcgatggctc ttggactttg cctccaagag 1200

 gaaagaagca gagcttcgca gcggcatcat cagaaacaac agcctgtggg 1250

 accggctgat cttccacaaa gtacagtcga gcctgggcgg aagagtccgg 1300

 ctgatggtga caggagccgc cccggtgtct gccactgtgc tgacgttcct 1350

 cagagcagcc ctgggctgtc agttttatga aggatacgga cagacagagt 1400

 gcactgccgg gtgctgccta accatgcctg gagactggac cgcaggccat 1450

 gttggggccc cgatgccgtg caatttgata aaacttgttg atgtggaaga 1500

 aatgaattac atggctgccg agggcgaggg cgaggtgtgt gtgaaagggc 1550

 caaatgtatt tcagggctac ttgaaggacc cagcgaaaac agcagaagct 1600

 ttggacaaag acggctggtt acacacaggg gacattggaa aatggttacc 1650

 aaatggcacc ttgaaaatta tcgaccggaa aaagcacata tttaagctgg 1700

 cacaaggaga atacatagcc cctgaaaaga ttgaaaatat ctacatgcga 1750

 agtgagcctg ttgctcaggt gtttgtccac ggagaaagcc tgcaggcatt 1800

 tctcattgca attgtggtac cagatgttga gacattatgt tcctgggccc 1850

 aaaagagagg atttgaaggg tcgtttgagg aactgtgcag aaataaggat 1900

 gtcaaaaaag ctatcctcga agatatggtg agacttggga aggattctgg 1950

 tctgaaacca tttgaacagg tcaaaggcat cacattgcac cctgaattat 2000

 tttctatcga caatggcctt ctgactccaa caatgaaggc gaaaaggcca 2050

 gagctgcgga actatttcag gtcgcagata gatgacctct attccactat 2100

 caaggtttag tgtgaagaag aaagctcaga ggaaatggca cagttccaca 2150

 atctcttctc ctgctgatgg ccttcatgtt gttaattttg aatacagcaa 2200

 gtgtagggaa ggaagcgttc gtgtttgact tgtccattcg gggttcttct 2250

 cataggaatg ctagaggaaa cagaacaccg ccttacagtc acctcatgtt 2300

 gcagaccatg tttatggtaa tacacacttt ccaaaatgag ccttaaaaat 2350

 tgtaaagggg atactataaa tgtgctaagt tatttgagac ttcctcagtt 2400

 taaaaagtgg gttttaaatc ttctgtctcc ctgcttttct aatcaagggg 2450

 ttaggacttt gctatctctg agatgtctgc tacttgctgc aaattctgca 2500

 gctgtctgct gctctaaaga gtacagtgca ctagagggaa gtgttccctt 2550

 taaaaataag aacaactgtc ctggctggag aatctcacaa gcggaccaga 2600

 gatcttttta aatccctgct actgtccctt ctcacaggca ttcacagaac 2650

 ccttctgatt cgtaagggtt acgaaactca tgttcttctc cagtcccctg 2700

 tggtttctgt tggagcataa ggtttccagt aagcgggagg gcagatccaa 2750

 ctcagaacca tgcagataag gagcctctgg caaatgggtg ctcatcagaa 2800

 cgcgtggatt ctctttcatg gcagaatgct cttggactcg gttctccagg 2850

 cctgattccc cgactccatc ctttttcagg ggttatttaa aaatctgcct 2900

 tagattctat agtgaagaca agcatttcaa gaaagagtta cctggatcag 2950

 ccatgctcag ctgtgacgcc tgaataactg tctactttat cttcactgaa 3000

 ccactcactc tgtgtaaagg ccaacagatt tttaatgtgg ttttcatatc 3050

 aaaagatcat gttgggatta acttgccttt ttccccaaaa aataaactct 3100

 caggcaagca tttctttaaa gctattaagg gagtatatac ttgagtactt 3150

 attgaaatgg acagtaataa gcaaatgttc ttataatgct acctgatttc 3200

 tatgaaatgt gtttgacaag ccaaaattct aggatgtaga aatctggaaa 3250

 gttcatttcc tgggattcac ttctccaggg attttttaaa gttaatttgg 3300

 gaaattaaca gcagttcact ttattgtgag tctttgccac atttgactga 3350

 attgagctgt catttgtaca tttaaagcag ctgttttggg gtctgtgaga 3400

 gtacatgtat tatatacaag cacaacaggg cttgcactaa agaattgtca 3450

 ttgtaataac actacttggt agcctaactt catatatgta ttcttaattg 3500

 cacaaaaagt caataatttg tcaccttggg gttttgaatg tttgctttaa 3550

 gtgttggcta tttctatgtt ttataaacca aaacaaaatt tccaaaaaca 3600

 atgaaggaaa ccaaaataaa tatttctgca tttcg 3635

<210> 511
<211> 698
<212> PRT
<213> Homo sapien

<400> 511
 Met Gln Ala His Glu Leu Phe Arg Tyr Phe Arg Met Pro Glu Leu
   1               5                  10                  15

 Val Asp Phe Arg Gln Tyr Val Arg Thr Leu Pro Thr Asn Thr Leu
                  20                  25                  30

 Met Gly Phe Gly Ala Phe Ala Ala Leu Thr Thr Phe Trp Tyr Ala
                  35                  40                  45

 Thr Arg Pro Lys Pro Leu Lys Pro Pro Cys Asp Leu Ser Met Gln
                  50                  55                  60

 Ser Val Glu Val Ala Gly Ser Gly Gly Ala Arg Arg Ser Ala Leu
                  65                  70                  75

 Leu Asp Ser Asp Glu Pro Leu Val Tyr Phe Tyr Asp Asp Val Thr
                  80                  85                  90

 Thr Leu Tyr Glu Gly Phe Gln Arg Gly Ile Gln Val Ser Asn Asn
                  95                 100                 105

 Gly Pro Cys Leu Gly Ser Arg Lys Pro Asp Gln Pro Tyr Glu Trp
                 110                 115                 120

 Leu Ser Tyr Lys Gln Val Ala Glu Leu Ser Glu Cys Ile Gly Ser
                 125                 130                 135

 Ala Leu Ile Gln Lys Gly Phe Lys Thr Ala Pro Asp Gln Phe Ile
                 140                 145                 150

 Gly Ile Phe Ala Gln Asn Arg Pro Glu Trp Val Ile Ile Glu Gln
                 155                 160                 165

 Gly Cys Phe Ala Tyr Ser Met Val Ile Val Pro Leu Tyr Asp Thr
                 170                 175                 180

 Leu Gly Asn Glu Ala Ile Thr Tyr Ile Val Asn Lys Ala Glu Leu
                 185                 190                 195

 Ser Leu Val Phe Val Asp Lys Pro Glu Lys Ala Lys Leu Leu Leu
                 200                 205                 210

 Glu Gly Val Glu Asn Lys Leu Ile Pro Gly Leu Lys Ile Ile Val
                 215                 220                 225

 Val Met Asp Ala Tyr Gly Ser Glu Leu Val Glu Arg Gly Gln Arg
                 230                 235                 240

 Cys Gly Val Glu Val Thr Ser Met Lys Ala Met Glu Asp Leu Gly
                 245                 250                 255

 Arg Ala Asn Arg Arg Lys Pro Lys Pro Pro Ala Pro Glu Asp Leu
                 260                 265                 270

 Ala Val Ile Cys Phe Thr Ser Gly Thr Thr Gly Asn Pro Lys Gly
                 275                 280                 285

 Ala Met Val Thr His Arg Asn Ile Val Ser Asp Cys Ser Ala Phe
                 290                 295                 300

 Val Lys Ala Thr Glu Asn Thr Val Asn Pro Cys Pro Asp Asp Thr
                 305                 310                 315

 Leu Ile Ser Phe Leu Pro Leu Ala His Met Phe Glu Arg Val Val
                 320                 325                 330

 Glu Cys Val Met Leu Cys His Gly Ala Lys Ile Gly Phe Phe Gln
                 335                 340                 345

 Gly Asp Ile Arg Leu Leu Met Asp Asp Leu Lys Val Leu Gln Pro
                 350                 355                 360

 Thr Val Phe Pro Val Val Pro Arg Leu Leu Asn Arg Met Phe Asp
                 365                 370                 375

 Arg Ile Phe Gly Gln Ala Asn Thr Thr Leu Lys Arg Trp Leu Leu
                 380                 385                 390

 Asp Phe Ala Ser Lys Arg Lys Glu Ala Glu Leu Arg Ser Gly Ile
                 395                 400                 405

 Ile Arg Asn Asn Ser Leu Trp Asp Arg Leu Ile Phe His Lys Val
                 410                 415                 420

 Gln Ser Ser Leu Gly Gly Arg Val Arg Leu Met Val Thr Gly Ala
                 425                 430                 435

 Ala Pro Val Ser Ala Thr Val Leu Thr Phe Leu Arg Ala Ala Leu
                 440                 445                 450

 Gly Cys Gln Phe Tyr Glu Gly Tyr Gly Gln Thr Glu Cys Thr Ala
                 455                 460                 465

 Gly Cys Cys Leu Thr Met Pro Gly Asp Trp Thr Ala Gly His Val
                 470                 475                 480

 Gly Ala Pro Met Pro Cys Asn Leu Ile Lys Leu Val Asp Val Glu
                 485                 490                 495

 Glu Met Asn Tyr Met Ala Ala Glu Gly Glu Gly Glu Val Cys Val
                 500                 505                 510

 Lys Gly Pro Asn Val Phe Gln Gly Tyr Leu Lys Asp Pro Ala Lys
                 515                 520                 525

 Thr Ala Glu Ala Leu Asp Lys Asp Gly Trp Leu His Thr Gly Asp
                 530                 535                 540

 Ile Gly Lys Trp Leu Pro Asn Gly Thr Leu Lys Ile Ile Asp Arg
                 545                 550                 555

 Lys Lys His Ile Phe Lys Leu Ala Gln Gly Glu Tyr Ile Ala Pro
                 560                 565                 570

 Glu Lys Ile Glu Asn Ile Tyr Met Arg Ser Glu Pro Val Ala Gln
                 575                 580                 585

 Val Phe Val His Gly Glu Ser Leu Gln Ala Phe Leu Ile Ala Ile
                 590                 595                 600

 Val Val Pro Asp Val Glu Thr Leu Cys Ser Trp Ala Gln Lys Arg
                 605                 610                 615

 Gly Phe Glu Gly Ser Phe Glu Glu Leu Cys Arg Asn Lys Asp Val
                 620                 625                 630

 Lys Lys Ala Ile Leu Glu Asp Met Val Arg Leu Gly Lys Asp Ser
                 635                 640                 645

 Gly Leu Lys Pro Phe Glu Gln Val Lys Gly Ile Thr Leu His Pro
                 650                 655                 660

 Glu Leu Phe Ser Ile Asp Asn Gly Leu Leu Thr Pro Thr Met Lys
                 665                 670                 675

 Ala Lys Arg Pro Glu Leu Arg Asn Tyr Phe Arg Ser Gln Ile Asp
                 680                 685                 690

 Asp Leu Tyr Ser Thr Ile Lys Val
                 695

<210> 512
<211> 2487
<212> DNA
<213> Homo sapien

<400> 512
 cctttcccct cccgccggac ctgccaggag gtgggctggc gcggagggag 50

 ggccctgtcc cctgtccctt taaggaggag ggccaaacgc cggcctagag 100

 tgcggcgtag cccccacccg ccgtgccctc accccagagc agctgcagcc 150

 tcagccggcc gcccctccgc cagccaagtc cgccgctctg acccccggca 200

 gcaagtcgcc accatggtga agatcgtgac agttaagacc caggcgtacc 250

 aggaccagaa gccgggcacg agcgggctgc ggaagcgggt gaaggtgttc 300

 cagagcagcg ccaactacgc ggagaacttc atccagagta tcatctccac 350

 cgtggagccg gcgcagcggc aggaggccac gctggtggtg ggcggggacg 400

 gccggttcta catgaaggag gccatccagc tcatcgctcg catcgctgcc 450

 gccaacggga tcggtcgctt ggttatcgga cagaatggaa tcctctccac 500

 ccctgctgta tcctgcatca ttagaaaaat caaagccatt ggtgggatca 550

 ttctgacagc cagtcacaac ccagggggcc ccaatggaga ttttggaatc 600

 aaattcaata tttctaatgg aggtcctgct ccagaagcaa taactgataa 650

 aattttccaa atcagcaaga caattgaaga atatgcagtt tgccctgacc 700

 tgaaagtaga ccttggtgtt ctgggaaagc agcagtttga cttggaaaat 750

 aagttcaaac ccttcacagt ggaaattgtg gattcggtag aagcttatgc 800

 tacaatgctg agaagcatct ttgatttcag tgcactgaaa gaactacttt 850

 ctgggccaaa ccgactgaag atccgtattg atgctatgca tggagttgtg 900

 ggaccgtatg taaagaagat cctctgtgaa gaactcggtg cccctgcgaa 950

 ctcggcagtt aactgcgttc ctctggagga ctttggaggc caccaccctg 1000

 accccaacct cacctatgca gctgacctgg tggagaccat gaagtcagga 1050

 gagcatgatt ttggggctgc ctttgatgga gatggggatc gaaacatgat 1100

 tctgggcaag catgggttct ttgtgaaccc ttcagactct gtggctgtca 1150

 ttgctgccaa catcttcagc attccgtatt tccagcagac tggggtccgc 1200

 ggctttgcac ggagcatgcc cacgagtggt gctctggacc gggtggctag 1250

 tgctacaaag attgctttgt atgagacccc aactggctgg aagttttttg 1300

 ggaatttgat ggacgcgagc aaactgtccc tttgtgggga ggagagcttc 1350

 gggaccggtt ctgaccacat ccgtgagaaa gatggactgt gggctgtcct 1400

 tgcctggctc tccatcctag ccacccgcaa gcagagtgtg gaggacattc 1450

 tcaaagatca ttggcaaaag tatggccgga atttcttcac caggtatgat 1500

 tacgaggagg tggaagctga gggcgcaaac aaaatgatga aggacttgga 1550

 ggccctgatg tttgatcgct cctttgtggg gaagcagttc tcagcaaatg 1600

 acaaagttta cactgtggag aaggccgata actttgaata cagcgaccca 1650

 gtggatggaa gcatttcaag aaatcagggc ttgcgcctca ttttcacaga 1700

 tggttctcga atcgtcttcc gactgagcgg cactgggagt gccggggcca 1750

 ccattcggct gtacatcgat agctatgaga aggacgttgc caagattaac 1800

 caggaccccc aggtcatgtt ggcccccctt atttccattg ctctgaaagt 1850

 gtcccagctg caggagagga cgggacgcac tgcacccact gtcatcacct 1900

 aagaagacag gcctgatgtg gtacgtccct ccacccccgg acccatccaa 1950

 gtcatctgat tgaagagcat gacagaaaca aaatgtattc accaagcatt 2000

 ttaggatttg actttttcac taaccagttg acgagcagtg catttacaag 2050

 gcactgccaa acaagatgcc cttgggagct gtgagggaaa gaggacctgc 2100

 gggcttagat caatctcaat tccttttcat gccctcctgc attgctgctg 2150

 cgtgggtatt tgtctcctta gccatcaggt acagtttaca ctacaatgta 2200

 agctataggt ggagcatcag cagtgagtga ggccattctt catccttagg 2250

 atgtggcaat gaaatgatgg tgcaagttcc tttctctttt gtgaatcttt 2300

 ccccccattt cctgtttaca tgtaacccaa caaaatgcaa tttctagtgc 2350

 cttctgtcca atcagttctt tcctctgagt gagacgtact tggctacaga 2400

 tttctgcctt gttttgcgac attgtcccat tcacacagat attttgggat 2450

 aataaaggaa aataagctac aaaaaaaaaa aaaaaaa 2487

<210> 513
<211> 562
<212> PRT
<213> Homo sapien

<400> 513
 Met Val Lys Ile Val Thr Val Lys Thr Gln Ala Tyr Gln Asp Gln
   1               5                  10                  15

 Lys Pro Gly Thr Ser Gly Leu Arg Lys Arg Val Lys Val Phe Gln
                  20                  25                  30

 Ser Ser Ala Asn Tyr Ala Glu Asn Phe Ile Gln Ser Ile Ile Ser
                  35                  40                  45

 Thr Val Glu Pro Ala Gln Arg Gln Glu Ala Thr Leu Val Val Gly
                  50                  55                  60

 Gly Asp Gly Arg Phe Tyr Met Lys Glu Ala Ile Gln Leu Ile Ala
                  65                  70                  75

 Arg Ile Ala Ala Ala Asn Gly Ile Gly Arg Leu Val Ile Gly Gln
                  80                  85                  90

 Asn Gly Ile Leu Ser Thr Pro Ala Val Ser Cys Ile Ile Arg Lys
                  95                 100                 105

 Ile Lys Ala Ile Gly Gly Ile Ile Leu Thr Ala Ser His Asn Pro
                 110                 115                 120

 Gly Gly Pro Asn Gly Asp Phe Gly Ile Lys Phe Asn Ile Ser Asn
                 125                 130                 135

 Gly Gly Pro Ala Pro Glu Ala Ile Thr Asp Lys Ile Phe Gln Ile
                 140                 145                 150

 Ser Lys Thr Ile Glu Glu Tyr Ala Val Cys Pro Asp Leu Lys Val
                 155                 160                 165

 Asp Leu Gly Val Leu Gly Lys Gln Gln Phe Asp Leu Glu Asn Lys
                 170                 175                 180

 Phe Lys Pro Phe Thr Val Glu Ile Val Asp Ser Val Glu Ala Tyr
                 185                 190                 195

 Ala Thr Met Leu Arg Ser Ile Phe Asp Phe Ser Ala Leu Lys Glu
                 200                 205                 210

 Leu Leu Ser Gly Pro Asn Arg Leu Lys Ile Arg Ile Asp Ala Met
                 215                 220                 225

 His Gly Val Val Gly Pro Tyr Val Lys Lys Ile Leu Cys Glu Glu
                 230                 235                 240

 Leu Gly Ala Pro Ala Asn Ser Ala Val Asn Cys Val Pro Leu Glu
                 245                 250                 255

 Asp Phe Gly Gly His His Pro Asp Pro Asn Leu Thr Tyr Ala Ala
                 260                 265                 270

 Asp Leu Val Glu Thr Met Lys Ser Gly Glu His Asp Phe Gly Ala
                 275                 280                 285

 Ala Phe Asp Gly Asp Gly Asp Arg Asn Met Ile Leu Gly Lys His
                 290                 295                 300

 Gly Phe Phe Val Asn Pro Ser Asp Ser Val Ala Val Ile Ala Ala
                 305                 310                 315

 Asn Ile Phe Ser Ile Pro Tyr Phe Gln Gln Thr Gly Val Arg Gly
                 320                 325                 330

 Phe Ala Arg Ser Met Pro Thr Ser Gly Ala Leu Asp Arg Val Ala
                 335                 340                 345

 Ser Ala Thr Lys Ile Ala Leu Tyr Glu Thr Pro Thr Gly Trp Lys
                 350                 355                 360

 Phe Phe Gly Asn Leu Met Asp Ala Ser Lys Leu Ser Leu Cys Gly
                 365                 370                 375

 Glu Glu Ser Phe Gly Thr Gly Ser Asp His Ile Arg Glu Lys Asp
                 380                 385                 390

 Gly Leu Trp Ala Val Leu Ala Trp Leu Ser Ile Leu Ala Thr Arg
                 395                 400                 405

 Lys Gln Ser Val Glu Asp Ile Leu Lys Asp His Trp Gln Lys Tyr
                 410                 415                 420

 Gly Arg Asn Phe Phe Thr Arg Tyr Asp Tyr Glu Glu Val Glu Ala
                 425                 430                 435

 Glu Gly Ala Asn Lys Met Met Lys Asp Leu Glu Ala Leu Met Phe
                 440                 445                 450

 Asp Arg Ser Phe Val Gly Lys Gln Phe Ser Ala Asn Asp Lys Val
                 455                 460                 465

 Tyr Thr Val Glu Lys Ala Asp Asn Phe Glu Tyr Ser Asp Pro Val
                 470                 475                 480

 Asp Gly Ser Ile Ser Arg Asn Gln Gly Leu Arg Leu Ile Phe Thr
                 485                 490                 495

 Asp Gly Ser Arg Ile Val Phe Arg Leu Ser Gly Thr Gly Ser Ala
                 500                 505                 510

 Gly Ala Thr Ile Arg Leu Tyr Ile Asp Ser Tyr Glu Lys Asp Val
                 515                 520                 525

 Ala Lys Ile Asn Gln Asp Pro Gln Val Met Leu Ala Pro Leu Ile
                 530                 535                 540

 Ser Ile Ala Leu Lys Val Ser Gln Leu Gln Glu Arg Thr Gly Arg
                 545                 550                 555

 Thr Ala Pro Thr Val Ile Thr
                 560

<210> 514
<211> 3396
<212> DNA
<213> Homo sapien

<400> 514
 aatctgccat tttctgtccc tgagtgagtc tctggcgtcc caaattgcct 50

 gtttttctcg caggctctat tccgttcgct ggttcgccac ctcaggggaa 100

 cgatggccat ggagtccaca gccactgccg ccgtcgccgc ggagctggtt 150

 tctgccgaca aaattgaaga tgttcctgct ccttctacat ctgcagataa 200

 agtggagagc aaccattaat ctgctttctg tcactgaaga tgggttgcat 250

 tttgtagaat attatctaaa tagaatcata catctggatg tggatagtga 300

 agctaagaaa ctattgggtt taggacagaa acatctggtg atgggggata 350

 ttccagcagc tgtcaatgca ttccaggaag cagctagtct tttaggtaag 400

 aagtatggag agacagctaa tgagtgtgga gaagccttct ttttctatgg 450

 gaaatcactt ctggagttgg caagaatgga gaatggtgtg ttgggaaacg 500

 ccttggaagg tgtgcatgtg gaagaggaag aaggagaaaa aacagaagat 550

 gaatctctgg tagaaaataa tgataacata gatgaggaag caagggaaga 600

 gttgagagaa caggtttatg acgccatggg agaaaaagaa gaagccaaaa 650

 aaacagaaga caagtctttg gcaaagcctg aaactgataa agaacaggac 700

 agtgaaatgg agaagggtgg aagagaagat atggatataa gtaaatctgc 750

 agaggagcca caggaaaaag ttgacttgac tctagattgg ttaactgaaa 800

 cctctgaaga ggcaaaagga ggagcagcac cagaaggacc gaatgaagct 850

 gaggtcactt ctgggaagcc agaacaggaa gtaccagatg ctgaggaaga 900

 aaaatcagtt tctggaactg atgtccaaga agagtgcaga gaaaaaggag 950

 gtcaggagaa gcagggagag gtaattgtga gcatagagga gaagccaaaa 1000

 gaagtttcag aagagcagcc tgtggtgact ctagaaaagc agggcactgc 1050

 agtggaggta gaagcagagt ctttagaccc gacagtcaag ccagtggatg 1100

 tgggtgggga cgagccagag gagaaggtag ttacctctga aaacgaggca 1150

 ggaaaggcgg ttcttgaaca actggtaggt caagaagtac cacctgctga 1200

 agagtcacca gaggtgacaa cagaggctgc agaggcctca gctgtagagg 1250

 ctggatcaga agtctctgaa aagcctgggc aggaggctcc agttctccct 1300

 aaggatggtg cagtcaatgg accgtcagtt gtaggagatc agactcctat 1350

 tgaaccacag acttctatag aaagactgac agaaacaaaa gatggctcag 1400

 gactagagga gaaggtcagg gcaaagctgg ttcctagtca ggaggagact 1450

 aagctgtctg tagaagagtc tgaggcagct ggagatgggg ttgataccaa 1500

 ggtagcccag ggagctactg agaaatcacc tgaagacaaa gttcagatag 1550

 ctgctaatga agagacacaa gagagagaag aacagatgaa agagggtgaa 1600

 gaaactgaag gctcagaaga ggatgataaa gaaaatgata agaccgaaga 1650

 aatgccaaat gattcagtcc ttgaaaacaa gtctcttcaa gaaaatgagg 1700

 aggaggagat tgggaaccta gagcttgcct gggatatgct ggatttagca 1750

 aagatcattt ttaaaaggca agaaacaaaa gaagcacagc tttatgctgc 1800

 ccaggcacat cttaaactcg gagaagttag tgttgaatct gaaaactatg 1850

 tgcaagctgt ggaggagttc cagtcctgcc ttaacctgca ggaacagtac 1900

 ctggaagccc acgaccgtct ccttgcagag acccactacc agctgggctt 1950

 ggcttatggg tacaactctc agtatgatga ggcagtggca cagttcagca 2000

 aatctattga agtcattgag aacagaatgg ctgtactaaa cgagcaggtg 2050

 aaggaggctg aaggatcgtc tgctgaatac aagaaagaaa ttgaggaact 2100

 aaaggaactg ctacccgaaa ttagagagaa gatagaagat gcaaaggagt 2150

 ctcagcgtag tgggaatgta gctgaactgg ctctgaaagc tactctggtg 2200

 gagagttcta cttcaggttt cactcctggt ggaggaggct cttcagtctc 2250

 catgattgcc agtagaaagc caacagacgg tgcttcctca tcaaattgtg 2300

 tgactgatat ttcccacctt gtcagaaaga agaggaaacc agaggaagag 2350

 agtccccgga aagatgatgc aaagaaagcc aaacaagagc cggaggtgaa 2400

 cggaggcagt ggggatgctg tccccagtgg aaatgaagtt tcggaaaaca 2450

 tggaggagga ggctgagaat caggctgaaa gccgggcagc agtggagggg 2500

 acagtggagg ctggagctac agttgaaagc actgcatgtt aagagggggc 2550

 acagccctcc tcccaaggga aagtgttttt gtatataatg tattttttca 2600

 cttttggagg attctttttg tataacttca ataaagattg taagcaaagg 2650

 ttgaggcttt gatggttttt ttcttaatta ttggctgaat ctgccttgga 2700

 gcactgctgg ttttatatat tagccaaagg ttttgttctg gccttctgta 2750

 ctgatctgtg ttcctgatcc taattcctat ctgtctaacg tggaggtgat 2800

 caagtgtggc tgtaggcctt tgttttccaa tggtgctata ttctgttttc 2850

 aaacacttca ctgaacccag ctgtcttgca aactttcagt ggtgctgtcc 2900

 ctggatgggg gctacaaaaa caagaattgg tgaagatctt gctcttcagt 2950

 gctgaaaatg gatgatggac tttggctgtg agccaggcct aggatggttc 3000

 ttgtcctata tccacctagt cttcacctgg ggctataatt ctgtcctgga 3050

 aaaagaactc tgaaaacctg ggtcagggga atgattccta aggaaaacgg 3100

 tctgcatttg agctctggtt tgaaagtagc caaggggact gatggtggac 3150

 actccagatg tggttggaag catatgtggg gaggctggct ggttgagttt 3200

 tgttattttc tgtatagaaa ggttgagata tatcaacact tggaattgtt 3250

 acccatctgc agaattgact tctcaaataa agatgctaaa aatctcaaaa 3300

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3350

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 3396

<210> 515
<211> 790
<212> PRT
<213> Homo sapien

<400> 515
 Met Phe Leu Leu Leu Leu His Leu Gln Ile Lys Trp Arg Ala Thr
   1               5                  10                  15

 Ile Asn Leu Leu Ser Val Thr Glu Asp Gly Leu His Phe Val Glu
                  20                  25                  30

 Tyr Tyr Leu Asn Arg Ile Ile His Leu Asp Val Asp Ser Glu Ala
                  35                  40                  45

 Lys Lys Leu Leu Gly Leu Gly Gln Lys His Leu Val Met Gly Asp
                  50                  55                  60

 Ile Pro Ala Ala Val Asn Ala Phe Gln Glu Ala Ala Ser Leu Leu
                  65                  70                  75

 Gly Lys Lys Tyr Gly Glu Thr Ala Asn Glu Cys Gly Glu Ala Phe
                  80                  85                  90

 Phe Phe Tyr Gly Lys Ser Leu Leu Glu Leu Ala Arg Met Glu Asn
                  95                 100                 105

 Gly Val Leu Gly Asn Ala Leu Glu Gly Val His Val Glu Glu Glu
                 110                 115                 120

 Glu Gly Glu Lys Thr Glu Asp Glu Ser Leu Val Glu Asn Asn Asp
                 125                 130                 135

 Asn Ile Asp Glu Glu Ala Arg Glu Glu Leu Arg Glu Gln Val Tyr
                 140                 145                 150

 Asp Ala Met Gly Glu Lys Glu Glu Ala Lys Lys Thr Glu Asp Lys
                 155                 160                 165

 Ser Leu Ala Lys Pro Glu Thr Asp Lys Glu Gln Asp Ser Glu Met
                 170                 175                 180

 Glu Lys Gly Gly Arg Glu Asp Met Asp Ile Ser Lys Ser Ala Glu
                 185                 190                 195

 Glu Pro Gln Glu Lys Val Asp Leu Thr Leu Asp Trp Leu Thr Glu
                 200                 205                 210

 Thr Ser Glu Glu Ala Lys Gly Gly Ala Ala Pro Glu Gly Pro Asn
                 215                 220                 225

 Glu Ala Glu Val Thr Ser Gly Lys Pro Glu Gln Glu Val Pro Asp
                 230                 235                 240

 Ala Glu Glu Glu Lys Ser Val Ser Gly Thr Asp Val Gln Glu Glu
                 245                 250                 255

 Cys Arg Glu Lys Gly Gly Gln Glu Lys Gln Gly Glu Val Ile Val
                 260                 265                 270

 Ser Ile Glu Glu Lys Pro Lys Glu Val Ser Glu Glu Gln Pro Val
                 275                 280                 285

 Val Thr Leu Glu Lys Gln Gly Thr Ala Val Glu Val Glu Ala Glu
                 290                 295                 300

 Ser Leu Asp Pro Thr Val Lys Pro Val Asp Val Gly Gly Asp Glu
                 305                 310                 315

 Pro Glu Glu Lys Val Val Thr Ser Glu Asn Glu Ala Gly Lys Ala
                 320                 325                 330

 Val Leu Glu Gln Leu Val Gly Gln Glu Val Pro Pro Ala Glu Glu
                 335                 340                 345

 Ser Pro Glu Val Thr Thr Glu Ala Ala Glu Ala Ser Ala Val Glu
                 350                 355                 360

 Ala Gly Ser Glu Val Ser Glu Lys Pro Gly Gln Glu Ala Pro Val
                 365                 370                 375

 Leu Pro Lys Asp Gly Ala Val Asn Gly Pro Ser Val Val Gly Asp
                 380                 385                 390

 Gln Thr Pro Ile Glu Pro Gln Thr Ser Ile Glu Arg Leu Thr Glu
                 395                 400                 405

 Thr Lys Asp Gly Ser Gly Leu Glu Glu Lys Val Arg Ala Lys Leu
                 410                 415                 420

 Val Pro Ser Gln Glu Glu Thr Lys Leu Ser Val Glu Glu Ser Glu
                 425                 430                 435

 Ala Ala Gly Asp Gly Val Asp Thr Lys Val Ala Gln Gly Ala Thr
                 440                 445                 450

 Glu Lys Ser Pro Glu Asp Lys Val Gln Ile Ala Ala Asn Glu Glu
                 455                 460                 465

 Thr Gln Glu Arg Glu Glu Gln Met Lys Glu Gly Glu Glu Thr Glu
                 470                 475                 480

 Gly Ser Glu Glu Asp Asp Lys Glu Asn Asp Lys Thr Glu Glu Met
                 485                 490                 495

 Pro Asn Asp Ser Val Leu Glu Asn Lys Ser Leu Gln Glu Asn Glu
                 500                 505                 510

 Glu Glu Glu Ile Gly Asn Leu Glu Leu Ala Trp Asp Met Leu Asp
                 515                 520                 525

 Leu Ala Lys Ile Ile Phe Lys Arg Gln Glu Thr Lys Glu Ala Gln
                 530                 535                 540

 Leu Tyr Ala Ala Gln Ala His Leu Lys Leu Gly Glu Val Ser Val
                 545                 550                 555

 Glu Ser Glu Asn Tyr Val Gln Ala Val Glu Glu Phe Gln Ser Cys
                 560                 565                 570

 Leu Asn Leu Gln Glu Gln Tyr Leu Glu Ala His Asp Arg Leu Leu
                 575                 580                 585

 Ala Glu Thr His Tyr Gln Leu Gly Leu Ala Tyr Gly Tyr Asn Ser
                 590                 595                 600

 Gln Tyr Asp Glu Ala Val Ala Gln Phe Ser Lys Ser Ile Glu Val
                 605                 610                 615

 Ile Glu Asn Arg Met Ala Val Leu Asn Glu Gln Val Lys Glu Ala
                 620                 625                 630

 Glu Gly Ser Ser Ala Glu Tyr Lys Lys Glu Ile Glu Glu Leu Lys
                 635                 640                 645

 Glu Leu Leu Pro Glu Ile Arg Glu Lys Ile Glu Asp Ala Lys Glu
                 650                 655                 660

 Ser Gln Arg Ser Gly Asn Val Ala Glu Leu Ala Leu Lys Ala Thr
                 665                 670                 675

 Leu Val Glu Ser Ser Thr Ser Gly Phe Thr Pro Gly Gly Gly Gly
                 680                 685                 690

 Ser Ser Val Ser Met Ile Ala Ser Arg Lys Pro Thr Asp Gly Ala
                 695                 700                 705

 Ser Ser Ser Asn Cys Val Thr Asp Ile Ser His Leu Val Arg Lys
                 710                 715                 720

 Lys Arg Lys Pro Glu Glu Glu Ser Pro Arg Lys Asp Asp Ala Lys
                 725                 730                 735

 Lys Ala Lys Gln Glu Pro Glu Val Asn Gly Gly Ser Gly Asp Ala
                 740                 745                 750

 Val Pro Ser Gly Asn Glu Val Ser Glu Asn Met Glu Glu Glu Ala
                 755                 760                 765

 Glu Asn Gln Ala Glu Ser Arg Ala Ala Val Glu Gly Thr Val Glu
                 770                 775                 780

 Ala Gly Ala Thr Val Glu Ser Thr Ala Cys
                 785                 790

<210> 516
<211> 2507
<212> DNA
<213> Homo sapien

<400> 516
 cagcacaccc cggcacctcc tctgcggcag ctgcgcctcg caagcgcagt 50

 gccgcagcgc acgccggagt ggctgtagct gcccggcgcg gcgccgccct 100

 gcgcgggctg tgggctgcgg gctgcgcccc cgctgctggc cagctctgca 150

 cggctgcggg ctctgcggcg cccggtgctc tgcaacgctg cggcgggcgg 200

 catgggataa cgcggccatg gtgcgccgag atcgcctccg caggatgagg 250

 gagtggtggg tccaggtggg gctgctggcc gtgcccctgc ttgctgcgta 300

 cctgcacatc ccaccccctc agctctcccc tgcccttcac tcatggaagt 350

 cttcaggcaa gtttttcact tacaagggac tgcgtatctt ctaccaagac 400

 tctgtgggtg tggttggaag tccagagata gttgtgcttt tacacggttt 450

 tccaacatcc agctacgact ggtacaagat ttgggaaggt ctgaccttga 500

 ggtttcatcg ggtgattgcc cttgatttct taggctttgg cttcagtgac 550

 aaaccgagac cacatcacta ttccatattt gagcaggcca gcatcgtgga 600

 agcgcttttg cggcatctgg ggctccagaa ccgcaggatc aaccttcttt 650

 ctcatgacta tggagatatt gttgctcagg agcttctcta caggtacaag 700

 cagaatcgat ctggtcggct taccataaag agtctctgtc tgtcaaatgg 750

 aggtatcttt cctgagactc accgtccact ccttctccaa aagctactca 800

 aagatggagg tgtgctgtca cccatcctca cacgactgat gaacttcttt 850

 gtattctctc gaggtctcac cccagtcttt gggccgtata ctcggccctc 900

 tgagagtgag ctgtgggaca tgtgggcagg gatccgcaac aatgacggga 950

 acttagtcat tgacagtctc ttacagtaca tcaatcagag gaagaagttc 1000

 agaaggcgct gggtgggagc tcttgcctct gtaactatcc ccattcattt 1050

 tatctatggg ccattggatc ctgtaaatcc ctatccagag tttttggagc 1100

 tgtacaggaa aacgctgccg cggtccacag tgtcgattct ggatgaccac 1150

 attagccact atccacagct agaggatccc atgggcttct tgaatgcata 1200

 tatgggcttc atcaactcct tctgagctgg aaagagtagc ttccctgtat 1250

 tacctcccct actcccttat gtgttgtgta ttccacttag gaagaaatgc 1300

 ccaaaagagg tcctggccat caaacataat tctctcacaa agtccacttt 1350

 actcaaattg gtgaacagtg tataggaaga agccagcagg agctctgact 1400

 aaggttgaca taatagtcca cctcccatta ctttgatatc tgatcaaatg 1450

 tatagacttg gctttgtttt ttgtgctatt aggaaattct gatgagcatt 1500

 actattcact gatgcagaaa gacgttcttt tgcataaaag actttttttt 1550

 aacactttgg acttctctga aatatttaga agtgctaatt tctggcccac 1600

 ccccaacagg aattctatag taaggaggag gagaaggggg gctccttccc 1650

 tctcctcgaa tgacgttatg ggcacatgcc ttttaaaagt tctttaagca 1700

 acacagagct gagtcctctt tgtcatacct ttggatttag tgtttcatca 1750

 gctgttttta gttataaaca ttttgttaaa atagatattg gtttaaatga 1800

 tacagtattt taggtatgat ttaagactat gatttaccta tacattatat 1850

 atattttata aagatactaa accagcatac ccttactctg ccagagtagt 1900

 gaagctaatt aaacacattt ggtttctgaa taaattgaac taaatccaaa 1950

 ctatttccta aaatcacagg acattaagga ccaatagcat ctgtgccaga 2000

 gatgtactgt tattagctgg gaagaccaat tctaacagca aataacagtc 2050

 tgagactcct catacctcag tggttagaag catgtctctc ttgagctaca 2100

 gtagagggga agggattgtt gtgtagtcaa gtcaccatgc tgaatgtaca 2150

 ctgattcctt tatgatgact gcttaactcc ccactgcctg tcccagagag 2200

 gctttccaat gtagctcagt aattcctgtt actttacaga caggaaagtt 2250

 ccagaaactt taagaacaaa ctctgaaaga cctatgagca aatggtgctg 2300

 aatacttttt ttttaaagcc acatttcatt gtcttagtca aagcaggatt 2350

 attaagtgat tatttaaaat tcgttttttt aaattagcaa cttcaagtat 2400

 aacaactttg aaactggaat aagtgtttat tttctattaa taaaaatgaa 2450

 ttgtgacaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2500

 aaaaaaa 2507

<210> 517
<211> 335
<212> PRT
<213> Homo sapien

<400> 517
 Met Val Arg Arg Asp Arg Leu Arg Arg Met Arg Glu Trp Trp Val
   1               5                  10                  15

 Gln Val Gly Leu Leu Ala Val Pro Leu Leu Ala Ala Tyr Leu His
                  20                  25                  30

 Ile Pro Pro Pro Gln Leu Ser Pro Ala Leu His Ser Trp Lys Ser
                  35                  40                  45

 Ser Gly Lys Phe Phe Thr Tyr Lys Gly Leu Arg Ile Phe Tyr Gln
                  50                  55                  60

 Asp Ser Val Gly Val Val Gly Ser Pro Glu Ile Val Val Leu Leu
                  65                  70                  75

 His Gly Phe Pro Thr Ser Ser Tyr Asp Trp Tyr Lys Ile Trp Glu
                  80                  85                  90

 Gly Leu Thr Leu Arg Phe His Arg Val Ile Ala Leu Asp Phe Leu
                  95                 100                 105

 Gly Phe Gly Phe Ser Asp Lys Pro Arg Pro His His Tyr Ser Ile
                 110                 115                 120

 Phe Glu Gln Ala Ser Ile Val Glu Ala Leu Leu Arg His Leu Gly
                 125                 130                 135

 Leu Gln Asn Arg Arg Ile Asn Leu Leu Ser His Asp Tyr Gly Asp
                 140                 145                 150

 Ile Val Ala Gln Glu Leu Leu Tyr Arg Tyr Lys Gln Asn Arg Ser
                 155                 160                 165

 Gly Arg Leu Thr Ile Lys Ser Leu Cys Leu Ser Asn Gly Gly Ile
                 170                 175                 180

 Phe Pro Glu Thr His Arg Pro Leu Leu Leu Gln Lys Leu Leu Lys
                 185                 190                 195

 Asp Gly Gly Val Leu Ser Pro Ile Leu Thr Arg Leu Met Asn Phe
                 200                 205                 210

 Phe Val Phe Ser Arg Gly Leu Thr Pro Val Phe Gly Pro Tyr Thr
                 215                 220                 225

 Arg Pro Ser Glu Ser Glu Leu Trp Asp Met Trp Ala Gly Ile Arg
                 230                 235                 240

 Asn Asn Asp Gly Asn Leu Val Ile Asp Ser Leu Leu Gln Tyr Ile
                 245                 250                 255

 Asn Gln Arg Lys Lys Phe Arg Arg Arg Trp Val Gly Ala Leu Ala
                 260                 265                 270

 Ser Val Thr Ile Pro Ile His Phe Ile Tyr Gly Pro Leu Asp Pro
                 275                 280                 285

 Val Asn Pro Tyr Pro Glu Phe Leu Glu Leu Tyr Arg Lys Thr Leu
                 290                 295                 300

 Pro Arg Ser Thr Val Ser Ile Leu Asp Asp His Ile Ser His Tyr
                 305                 310                 315

 Pro Gln Leu Glu Asp Pro Met Gly Phe Leu Asn Ala Tyr Met Gly
                 320                 325                 330

 Phe Ile Asn Ser Phe
                 335

<210> 518
<211> 1324
<212> DNA
<213> Homo sapien

<400> 518
 cggcacgagc gccgccgagg attcagcagc ctcccccttg agccccctcg 50

 cttcccgacg ttccgttccc ccctgcccgc cttctcccgc caccgccgcc 100

 gccgccttcc gcaggccgtt tccaccgagg aaaaggaatc gtatcgtatg 150

 tccgctatcc agaacctcca ctctttcgac ccctttgctg atgcaagtaa 200

 gggtgatgac ctgcttcctg ctggcactga ggattatatc catataagaa 250

 ttcaacagag aaacggcagg aagaccctta ctactgtcca agggatcgct 300

 gatgattacg ataaaaagaa actagtgaag gcgtttaaga aaaagtttgc 350

 ctgcaatggt actgtaattg agcatccgga atatggagaa gtaattcagc 400

 tacagggtga ccaacgcaag aacatatgcc agttcctcgt agagattgga 450

 ctggctaagg acgatcagct gaaggttcat gggttttaag tgcttgtggc 500

 tcactgaagc ttaagtgagg atttccttgc aatgagtaga atttcccttc 550

 tctcccttgt cacaggttta aaaacctcac agcttgtata atgtaaccat 600

 ttggggtccg cttttaactt ggactagtgt aactccttca tgcaataaac 650

 tgaaaagagc catgctgtct agtcttgaag tccctcattt aaacagaggt 700

 caagcaatag gcgcctggca gtgtcaagcc tgaaaccaag caataccgtc 750

 atgtttcagc caagcccaga gccctaagat tacaaacaac tatggccgga 800

 acctcctcag ctctccctct gcagagttcc ctaccctaag agaatgttac 850

 cacctgaaca gtcctcggtg aatctgagag gagaggatgg ggtaaggcag 900

 aagcaccagc tgtactacta gaagggagct tttggtggta gatcccctgg 950

 tgtctccaac ctgactaggt ggacagagct caaagaggcc ctcttaccgc 1000

 tagcgaggtg ataggacatc tggcttgcca caaaggtctg ttcgaccaga 1050

 catatcctag ctaagggatg tccaaacatc agaatgtgag gccaaccttc 1100

 tatcagagtt aaacttttga caagggaaca aatctcaaac tgatccatca 1150

 gtcatgtagc tagctgtaga gcttgcaact taatagcagc agctgcccaa 1200

 tgccatgtga agtaacaaac tggtttttgg tttttttttc cccttcagtt 1250

 ttaatgttat gtgtaatgta tttaaaccct tatttaaata aaacttgttt 1300

 tcagaaaaaa aaaaaaaaaa aaaa 1324

<210> 519
<211> 113
<212> PRT
<213> Homo sapien

<400> 519
 Met Ser Ala Ile Gln Asn Leu His Ser Phe Asp Pro Phe Ala Asp
   1               5                  10                  15

 Ala Ser Lys Gly Asp Asp Leu Leu Pro Ala Gly Thr Glu Asp Tyr
                  20                  25                  30

 Ile His Ile Arg Ile Gln Gln Arg Asn Gly Arg Lys Thr Leu Thr
                  35                  40                  45

 Thr Val Gln Gly Ile Ala Asp Asp Tyr Asp Lys Lys Lys Leu Val
                  50                  55                  60

 Lys Ala Phe Lys Lys Lys Phe Ala Cys Asn Gly Thr Val Ile Glu
                  65                  70                  75

 His Pro Glu Tyr Gly Glu Val Ile Gln Leu Gln Gly Asp Gln Arg
                  80                  85                  90

 Lys Asn Ile Cys Gln Phe Leu Val Glu Ile Gly Leu Ala Lys Asp
                  95                 100                 105

 Asp Gln Leu Lys Val His Gly Phe
                 110

<210> 520
<211> 368
<212> DNA
<213> Homo sapien

<400> 520
 ctttttcgtc cttttccccg gttgctgctt gctgtgagtg tctctagggt 50

 gatacgtggg tgagaaaggt cctggtccgc gccagagccc agcgcgcctc 100

 gtcgccatgc ctcggaaaat tgaggaaatc aaggacttcc tgctcacagc 150

 ccgacgaaag gatgccaaat ctgtcaagat caagaaaaat aaggacaacg 200

 tgaagtttaa agttcgatgc agcagatacc tttacaccct ggtcatcact 250

 gacaaagaga aggcagagaa actgaagcag tccctgcccc ccggtttggc 300

 agtgaaggaa ctgaaatgaa ccagacacac tgattggaac tgtattatat 350

 taaaatacta aaaatcct 368

<210> 521
<211> 70
<212> PRT
<213> Homo sapien

<400> 521
 Met Pro Arg Lys Ile Glu Glu Ile Lys Asp Phe Leu Leu Thr Ala
   1               5                  10                  15

 Arg Arg Lys Asp Ala Lys Ser Val Lys Ile Lys Lys Asn Lys Asp
                  20                  25                  30

 Asn Val Lys Phe Lys Val Arg Cys Ser Arg Tyr Leu Tyr Thr Leu
                  35                  40                  45

 Val Ile Thr Asp Lys Glu Lys Ala Glu Lys Leu Lys Gln Ser Leu
                  50                  55                  60

 Pro Pro Gly Leu Ala Val Lys Glu Leu Lys
                  65                  70

<210> 522
<211> 2701
<212> DNA
<213> Homo sapien

<400> 522
 gttgctgcgg agccaggagg ggaagcgatg gctgggcccg cgtggatctc 50

 taaggtctct cggctgctgg gggcattcca caacccaaaa caggtgacca 100

 gaggttttac tggtggtgtt cagacagtaa ctttaattcc aggagatggt 150

 attggcccag aaatttcagc tgcagttatg aagatttttg atgctgccaa 200

 agcacctatt cagtgggagg agcggaacgt cactgccatt caaggacctg 250

 gaggaaagtg gatgatccct tcagaggcta aagagtccat ggataagaac 300

 aagatgggct tgaaaggccc tttgaagacc ccaatagcag ccggtcaccc 350

 atctatgaat ttactgctgc gcaaaacatt tgacctttac gcgaatgtcc 400

 gaccatgtgt ctctatcgaa ggctataaaa ccccttacac cgatgtaaat 450

 attgtgacca ttcgagagaa cacagaagga gaatacagtg gaattgagca 500

 tgtgattgtt gatggagtcg tgcagagtat caagctcatc accgaggggg 550

 cgagcaagcg cattgctgag tttgcctttg agtatgcccg gaacaaccac 600

 cggagcaacg tcacggcggt gcacaaagcc aacatcatgc ggatgtcaga 650

 tgggcttttt ctacaaaaat gcagggaagt tgcagaaagc tgtaaagata 700

 ttaaatttaa tgagatgtac cttgatacag tatgtttgaa tatggtacaa 750

 gatccttccc aatttgatgt tcttgttatg ccaaatttgt atggagacat 800

 ccttagtgac ttgtgtgcag gattgatcgg aggtctcggt gtgacaccaa 850

 gtggcaacat tggagccaat ggggttgcaa tttttgagtc ggttcatggg 900

 acggctccag acattgcagg caaggacatg gcgaatccca cagccctcct 950

 gctcagtgcc gtgatgatgc tgcgccacat gggacttttt gaccatgctg 1000

 caagaattga ggctgcgtgt tttgctacaa ttaaggacgg aaagagcttg 1050

 acaaaagatt tgggaggcaa tgcaaaatgc tcagacttca cagaggaaat 1100

 ctgtcgccga gtaaaagatt tagattaaca cttctacaac tggcatttac 1150

 atcagtcact ctaaatggac accacatgaa cctctgttta gaatacctac 1200

 gtatgtatgc attggtttgc ttgtttcttg acagtacatt tttagatctg 1250

 gccttttctt aacaaaatct gtgcaaaaga tgcaggtgga tgtccctagg 1300

 tctgttttca aagaactttt tccaagtgct tgttttattt attaagtgtc 1350

 tacctggtaa atgttttttt tgtaaactct gagtggactg tatcatttgc 1400

 tattctaaac cattttacac ttaagttaaa atagtttctc ttcagctgta 1450

 aataacagga tacagaatta acaagagaaa atgtctaact ttttaagaaa 1500

 aaccttattt tcttcggttt ttgaaaaaca taatggaaat aaaacaggat 1550

 attgacataa tagcacaaaa tgacactctt ctaaaactaa atgggcacaa 1600

 gagaattttc ctgggaaagt tcacatcaaa aagagtgaat gtggtatatt 1650

 tctaaatgat atggaaaata gagacagatt tgtcctttac agaaattact 1700

 gagtgtgaat aaaaacttca gatccaagaa atatataatg agagatataa 1750

 tttttgttaa taagacaaag gtaatatatt ggatacaaag acacaaatgt 1800

 attgtgtgtt caattatttt gttgtcttga gatttaatat tctttccaag 1850

 agcttttaat gaagcagaga gctagtactt cattttcact ggatacattt 1900

 tcagcatcat gagttgtcac agcctctgag cccctgatct gaagccagaa 1950

 gggctgagtg tattgtaaac ttattcttgc atgttgctgt ctgggaatgg 2000

 accacactac agcaggtagt tctgggggcg atactgccga aaggcccgaa 2050

 cacatgtatt ttggctgcaa ttgaggaact tgggatgcta ttaattttgt 2100

 atttcagcaa ctgccccttc tcctatccca aagcaccaat tactgccctc 2150

 tgcctcagca gtaccagtat aagatgacat tccaaagact ggaggcaact 2200

 cagcctgagt taattcacaa aattatgcca tgctggggct tgagcttgag 2250

 cttgggctta ggcttgggct cagcttttga ccctcaggca tctcctttcc 2300

 cttcctgtct tcctctccct tctcctctgc tgcagcatga ttttcttaat 2350

 cttcagacac tcactatttt catgaacagt taccctctgt ccccacaacc 2400

 aaagacaact catggcctcc tttggccctt gtgtaacatt gcaaacctgt 2450

 ggctttgcaa aatgtaccca ggtcacaagg ggattttttt ttttttagca 2500

 atgatatccc tgtctgggtc actttttaag cttgtaaccg cccccccaga 2550

 cttataatct taaatgtatt ttcctttgtt taagctgctg cttcctctgt 2600

 ttcattggat tgtgccagtt atcagtggct cttgggttca aagtaataaa 2650

 gaattccaaa actgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2700

 a 2701

<210> 523
<211> 366
<212> PRT
<213> Homo sapien

<400> 523
 Met Ala Gly Pro Ala Trp Ile Ser Lys Val Ser Arg Leu Leu Gly
   1               5                  10                  15

 Ala Phe His Asn Pro Lys Gln Val Thr Arg Gly Phe Thr Gly Gly
                  20                  25                  30

 Val Gln Thr Val Thr Leu Ile Pro Gly Asp Gly Ile Gly Pro Glu
                  35                  40                  45

 Ile Ser Ala Ala Val Met Lys Ile Phe Asp Ala Ala Lys Ala Pro
                  50                  55                  60

 Ile Gln Trp Glu Glu Arg Asn Val Thr Ala Ile Gln Gly Pro Gly
                  65                  70                  75

 Gly Lys Trp Met Ile Pro Ser Glu Ala Lys Glu Ser Met Asp Lys
                  80                  85                  90

 Asn Lys Met Gly Leu Lys Gly Pro Leu Lys Thr Pro Ile Ala Ala
                  95                 100                 105

 Gly His Pro Ser Met Asn Leu Leu Leu Arg Lys Thr Phe Asp Leu
                 110                 115                 120

 Tyr Ala Asn Val Arg Pro Cys Val Ser Ile Glu Gly Tyr Lys Thr
                 125                 130                 135

 Pro Tyr Thr Asp Val Asn Ile Val Thr Ile Arg Glu Asn Thr Glu
                 140                 145                 150

 Gly Glu Tyr Ser Gly Ile Glu His Val Ile Val Asp Gly Val Val
                 155                 160                 165

 Gln Ser Ile Lys Leu Ile Thr Glu Gly Ala Ser Lys Arg Ile Ala
                 170                 175                 180

 Glu Phe Ala Phe Glu Tyr Ala Arg Asn Asn His Arg Ser Asn Val
                 185                 190                 195

 Thr Ala Val His Lys Ala Asn Ile Met Arg Met Ser Asp Gly Leu
                 200                 205                 210

 Phe Leu Gln Lys Cys Arg Glu Val Ala Glu Ser Cys Lys Asp Ile
                 215                 220                 225

 Lys Phe Asn Glu Met Tyr Leu Asp Thr Val Cys Leu Asn Met Val
                 230                 235                 240

 Gln Asp Pro Ser Gln Phe Asp Val Leu Val Met Pro Asn Leu Tyr
                 245                 250                 255

 Gly Asp Ile Leu Ser Asp Leu Cys Ala Gly Leu Ile Gly Gly Leu
                 260                 265                 270

 Gly Val Thr Pro Ser Gly Asn Ile Gly Ala Asn Gly Val Ala Ile
                 275                 280                 285

 Phe Glu Ser Val His Gly Thr Ala Pro Asp Ile Ala Gly Lys Asp
                 290                 295                 300

 Met Ala Asn Pro Thr Ala Leu Leu Leu Ser Ala Val Met Met Leu
                 305                 310                 315

 Arg His Met Gly Leu Phe Asp His Ala Ala Arg Ile Glu Ala Ala
                 320                 325                 330

 Cys Phe Ala Thr Ile Lys Asp Gly Lys Ser Leu Thr Lys Asp Leu
                 335                 340                 345

 Gly Gly Asn Ala Lys Cys Ser Asp Phe Thr Glu Glu Ile Cys Arg
                 350                 355                 360

 Arg Val Lys Asp Leu Asp
                 365

<210> 524
<211> 2613
<212> DNA
<213> Homo sapien

<400> 524
 gcgcgccttc tccagtccgc ggtgccatgg cccccgcccg tctgttcgcg 50

 ctgctgctgc tcttcgtagg cggagtcgcc gagtcgatcc gagagactga 100

 ggtcatcgac ccccaggacc tcctagaagg ccgatacttc tccggagccc 150

 taccagacga tgaggatgta gtggggcccg ggcaggaatc tgatgacttt 200

 gagctgtctg gctctggaga tctggatgac ttggaagact ccatgatcgg 250

 ccctgaagtt gtccatccct tggtgcctct agataaccat atccctgaga 300

 gggcagggtc tgggagccaa gtccccaccg aacccaagaa actagaggag 350

 aatgaggtta tccccaagag aatctcaccc gttgaagaga gtgaggatgt 400

 gtccaacaag gtgtcaatgt ccagcactgt gcagggcagc aacatctttg 450

 agagaacgga ggtcctggca gctctgattg tgggtggcat cgtgggcatc 500

 ctctttgccg tcttcctgat cctactgctc atgtaccgta tgaagaagaa 550

 ggatgaaggc agctatgacc tgggcaagaa acccatctac aagaaagccc 600

 ccaccaatga gttctacgcg tgaagcttgc ttgtgggcac tggcttggac 650

 tttagcgggg agggaagcca ggggattttg aagggtggac attagggtag 700

 ggtgaggtca acctaatact gacttgtcag tatctccagc tctgattacc 750

 tttgaagtgt tcagaagaga cattgtcttc tactgttctg ccaggttctt 800

 cttgagcttt gggcctcagt tgccctggca gaaaaatgga ttcaacttgg 850

 cctttctgaa ggcaagactg ggattggatc acttcttaaa cttccagtta 900

 agaatctagg tccgccctca agcccatact gaccatgcct catccagagc 950

 tcctctgaag ccagggggct aacggatgtt gtgtggagtc ctggctggag 1000

 gtcctccccc agtggccttc ctcccttcct ttcacagccg gtctctctgc 1050

 caggaaatgg gggaaggaac tagaaccacc tgcaccttga gatgtttctg 1100

 taaatgggta cttgtgatca cactacggga atctctgtgg tatatacctg 1150

 gggccattct aggctctttc aagtgacttt tggaaatcaa ccttttttat 1200

 ttggggggga ggatggggaa aagagctgag agtttatgct gaaatggatt 1250

 tatagaatat ttgtaaatct atttttagtg tttgttcgtt tttttaactg 1300

 ttcattcctt tgtgcagagt gtatatctct gcctgggcaa gagtgtggag 1350

 gtgccgaggt gtcttcattc tctcgcacat ttccacagca cctgctaagt 1400

 ttgtatttaa tggtttttgt ttttgttttt gtttgtttct tgaaaatgag 1450

 agaagagccg gagagatgat ttttattaat tttttttttt tttttttttt 1500

 tactatttat agctttagat agggcctccc ttcccctctt ctttctttgt 1550

 tctctttcat taaacccctt ccccagtttt ttttttatac tttaaacccc 1600

 gctcctcatg gccttggccc tttctgaagc tgcttcctct tataaaatag 1650

 cttttgccga aacatagttt ttttttagca gatcccaaaa tataatgaag 1700

 gggatggtgg gatatttgtg tctgtgttct tataatatat tattattctt 1750

 ccttggttct agaaaaatag ataaatatat ttttttcagg aaatagtgtg 1800

 gtgtttccag tttgatgttg ctgggtggtt gagtgagtga attttcatgt 1850

 ggctgggtgg gtttttgcct ttttctcttg ccctgttcct ggtgccttct 1900

 gatggggctg gaatagttga ggtggatggt tctacccttt ctgccttctg 1950

 tttgggaccc agctggtgtt ctttggtttg ctttcttcag gctctagggc 2000

 tgtgctatcc aatacagtaa ccacatgcgg ctgtttaaag ttaagccaat 2050

 taaaatcaca taagattaaa aattccttcc tcagttgcac taaccacgtt 2100

 tctagaggcg tcactgtatg tagttcatgg ctactgtact gacagcgaga 2150

 gcatgtccat ctgttggaca gcactattct agagaactaa actggcttaa 2200

 cgagtcacag cctcagctgt gctgggacga cccttgtctc cctgggtagg 2250

 ggggggggaa tgggggaggg ctgatgaggc cccagctggg gcctgttgtc 2300

 tgggaccctc cctctcctga gaggggaggc ctggtggctt agcctgggca 2350

 ggtcgtgtct cctcctgacc ccagtggctg cggtgagggg aaccaccctc 2400

 ccttgctgca ccagtggcca ttagctcccg tcaccactgc aacccagggt 2450

 cccagctggc tgggtcctct tctgccccca gtgcccttcc ccttgggctg 2500

 tgttggagtg agcacctcct ctgtaggcac ctctcacact gttgtctgtt 2550

 actgattttt tttgataaaa agataataaa acctggtact ttctaaaaaa 2600

 aaaaaaaaaa aaa 2613

<210> 525
<211> 198
<212> PRT
<213> Homo sapien

<400> 525
 Met Ala Pro Ala Arg Leu Phe Ala Leu Leu Leu Leu Phe Val Gly
   1               5                  10                  15

 Gly Val Ala Glu Ser Ile Arg Glu Thr Glu Val Ile Asp Pro Gln
                  20                  25                  30

 Asp Leu Leu Glu Gly Arg Tyr Phe Ser Gly Ala Leu Pro Asp Asp
                  35                  40                  45

 Glu Asp Val Val Gly Pro Gly Gln Glu Ser Asp Asp Phe Glu Leu
                  50                  55                  60

 Ser Gly Ser Gly Asp Leu Asp Asp Leu Glu Asp Ser Met Ile Gly
                  65                  70                  75

 Pro Glu Val Val His Pro Leu Val Pro Leu Asp Asn His Ile Pro
                  80                  85                  90

 Glu Arg Ala Gly Ser Gly Ser Gln Val Pro Thr Glu Pro Lys Lys
                  95                 100                 105

 Leu Glu Glu Asn Glu Val Ile Pro Lys Arg Ile Ser Pro Val Glu
                 110                 115                 120

 Glu Ser Glu Asp Val Ser Asn Lys Val Ser Met Ser Ser Thr Val
                 125                 130                 135

 Gln Gly Ser Asn Ile Phe Glu Arg Thr Glu Val Leu Ala Ala Leu
                 140                 145                 150

 Ile Val Gly Gly Ile Val Gly Ile Leu Phe Ala Val Phe Leu Ile
                 155                 160                 165

 Leu Leu Leu Met Tyr Arg Met Lys Lys Lys Asp Glu Gly Ser Tyr
                 170                 175                 180

 Asp Leu Gly Lys Lys Pro Ile Tyr Lys Lys Ala Pro Thr Asn Glu
                 185                 190                 195

 Phe Tyr Ala


<210> 526
<211> 1500
<212> DNA
<213> Homo sapien

<400> 526
 ctgcctgaca tagacacgtt acagattcac gtgatggatt gcatcattta 50

 agtgttgatg tatcacctcc ccaaaactgt tggtaaatgt cagatttttt 100

 cctccaagag ttgtgctttt gtgttatttg ttttcactca aatattttgc 150

 ctcattattc ttgttttaaa agaaagaaaa caggccgggc acagtggctc 200

 atgcctgtaa tcccagcact ttgggaggtc gaggtgggtg gatcacttgg 250

 ggtcagggtt tgagaccagc ctggccaaca tggcggaacc ctgtctctac 300

 caaaattaca aaaattagcc gagcatggtg gcgcatgcct gtagtcgcag 350

 ctactcgcga ggttgaggca ggagaattgc ttgaacccag gaagtggcag 400

 ttgcagtgag ccgagacgac accactgcac tccagcctgg gtgacagagg 450

 gagactctgt ctcgaaagaa agaaagaaaa aaaggaagga aggagaagga 500

 aggaaggaga agaaaaggta cctgttctac gtagaacacc tttggtggag 550

 ttccatcaac tcgcaaagta gaatccttac ctactactct tctgataata 600

 attttaatat tttttatgtt tggttgatgc gagcagctgc actgctcatg 650

 cagttagcta gcatgtgaca tcatgtgaca aagttcatgt aattagatgg 700

 aagaaacctc actgattaat tttaagaacc ttttagggat gcaggaacaa 750

 tgaagtggcc acagtatgtg ctgtttttga agcattttta aaaacgaatt 800

 gtagttgttt ttcttcattt aaaatggatc tgttggaggt tatgtgtgta 850

 tgttgtagtt ttattgcagc cacaataatt ttaccaaagt tttcacatag 900

 gcagttagcc tttacttaat atcaagacaa gtgaaaaaat attggcatcg 950

 atgaaaccga taacattggc ctcattggat ttctttaccc attcacagtg 1000

 taaagaagtt accttcatgc tttcattgta cctgcaggcc tgtgggcttg 1050

 tacagtagat aattaatttc taaaaagaac agctgcctat tttcttccta 1100

 ggttaggtta tatcttcata atcacaagaa ttagtgatgg caaaataaaa 1150

 ttttgcttat gaatctttta cattgtttat atatgattaa tatcatcata 1200

 tatattttct gtattaagct catttggctt catttaagct gtatacttag 1250

 tcatatatct ttcattagtt ctatggatat gagcagatcc ctttactgga 1300

 gcccagtatg tgctgtgtga gttagaagtc attcttgctg agaaggtgaa 1350

 taggtaggga tttgccttgt tttgtaagtc tacaatttgc caagagtaaa 1400

 taacactgga ccagctgtaa aagtaaacag tgtgtttatg cattgagata 1450

 ctaaagcatt taagaaaaaa ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1500

<210> 527
<211> 16
<212> PRT
<213> Homo sapien

<400> 527
 Leu Pro Asp Ile Asp Thr Leu Gln Ile His Val Met Asp Cys Ile
   1               5                  10                  15

 Ile


<210> 528
<211> 663
<212> DNA
<213> Homo sapien

<400> 528
 agtgcatcct gggttggcgt agccatggcg tctcgtgtcc tttcagccta 50

 tgtcagccgc ctgcccgcgg cctttgcgcc gctgccccgg gtccggatgc 100

 tggccgtggc ccggcctctc agcactgctc tctgctccgc ggggacccag 150

 acgaggctcg ggactttgca gccggcctta gtgctcgcgc aggttcctgg 200

 tagagttaca cagttgtgcc gccagtatag cgacatgcct cctttgacgt 250

 tagagggcat ccaggaccgt gttctttacg tattgaaact ctatgacaag 300

 attgacccag agaagctttc agtaaattct cattttatga aagacctggg 350

 cttagacagt ttggaccaag tggagattat catggccatg gaagacgaat 400

 ttgggtttga aattcctgat atagatgctg aaaagttaat gtgtccacaa 450

 gaaattgtag attacattgc agataagaaa gatgtatatg aataaagtat 500

 cagacccttt ggctttgctg agagaggact cagatgatag tgacgaatgt 550

 ctggcagtga ggacacattt tggcattctt gctgactctg acagagtgat 600

 tctgatggac ttgtatttaa attgtatgtg ttttactctt tgaaaataaa 650

 tctataaaac caa 663

<210> 529
<211> 156
<212> PRT
<213> Homo sapien

<400> 529
 Met Ala Ser Arg Val Leu Ser Ala Tyr Val Ser Arg Leu Pro Ala
   1               5                  10                  15

 Ala Phe Ala Pro Leu Pro Arg Val Arg Met Leu Ala Val Ala Arg
                  20                  25                  30

 Pro Leu Ser Thr Ala Leu Cys Ser Ala Gly Thr Gln Thr Arg Leu
                  35                  40                  45

 Gly Thr Leu Gln Pro Ala Leu Val Leu Ala Gln Val Pro Gly Arg
                  50                  55                  60

 Val Thr Gln Leu Cys Arg Gln Tyr Ser Asp Met Pro Pro Leu Thr
                  65                  70                  75

 Leu Glu Gly Ile Gln Asp Arg Val Leu Tyr Val Leu Lys Leu Tyr
                  80                  85                  90

 Asp Lys Ile Asp Pro Glu Lys Leu Ser Val Asn Ser His Phe Met
                  95                 100                 105

 Lys Asp Leu Gly Leu Asp Ser Leu Asp Gln Val Glu Ile Ile Met
                 110                 115                 120

 Ala Met Glu Asp Glu Phe Gly Phe Glu Ile Pro Asp Ile Asp Ala
                 125                 130                 135

 Glu Lys Leu Met Cys Pro Gln Glu Ile Val Asp Tyr Ile Ala Asp
                 140                 145                 150

 Lys Lys Asp Val Tyr Glu
                 155

<210> 530
<211> 4484
<212> DNA
<213> Homo sapien

<400> 530
 tgcccaggag gagtaggagc aggagcagaa gcagaagcgg ggtccggagc 50

 tgcgcgccta cgcgggacct gtgtccgaaa tgccggtgcg aggagaccgc 100

 gggtttccac cccggcggga gctgtcaggt tggctccgcg ccccaggcat 150

 ggaagagctg atatgggaac agtacactgt gaccctacaa aaggattcca 200

 aaagaggatt tggaattgca gtgtccggag gcagagacaa cccccacttt 250

 gaaaatggag aaacgtcaat tgtcatttct gatgtgctcc cgggtgggcc 300

 tgctgatggg ctgctccaag aaaatgacag agtggtcatg gtcaatggca 350

 cccccatgga ggatgtgctt cattcgtttg cagttcagca gctcagaaaa 400

 agtgggaagg tcgctgctat tgtggtcaag aggccccgga aggtccaggt 450

 ggccgcactt caggccagcc ctcccctgga tcaggatgac cgggcttttg 500

 aggtgatgga cgagtttgat ggcagaagtt tccggagtgg ctacagcgag 550

 aggagccggc tgaacagcca tggggggcgc agccgcagct gggaggacag 600

 cccggaaagg gggcgtcccc atgagcgggc ccggagccgg gagcgggacc 650

 tcagccggga ccggagccgt ggccggagcc tggagcgggg cctggaccaa 700

 gaccatgcgc gcacccgaga ccgcagccgt ggccggagcc tggagcgggg 750

 cctggaccac gactttgggc catcccggga ccgggaccgt gaccgcagcc 800

 gcggccggag cattgaccag gactacgagc gagcctatca ccgggcctac 850

 gacccagact acgagcgggc ctacagcccg gagtacaggc gcggggcccg 900

 ccacgatgcc cgctctcggg gaccccgaag ccgcagccgc gagcacccgc 950

 actcacggag ccccagcccc gagcctaggg ggcggccggg gcccatcggg 1000

 gtcctcctga tgaaaagcag agcgaacgaa gagtatggtc tccggcttgg 1050

 gagtcagatc ttcgtaaagg aaatgacccg aacgggtctg gcaactaaag 1100

 atggcaacct tcacgaagga gacataattc tcaagatcaa tgggactgta 1150

 actgagaaca tgtctttaac ggatgctcga aaattgatag aaaagtcaag 1200

 aggaaaacta cagctagtgg tgttgagaga cagccagcag accctcatca 1250

 acatcccgtc attaaatgac agtgactcag aaatagaaga tatttcagaa 1300

 atagagtcaa cccgatcatt ttctccagag gagagacgtc atcagtattc 1350

 tgattatgat tatcattcct caagtgagaa gctgaaggaa aggccaagtt 1400

 ccagagagga cacgccgagc agattgtcca ggatgggtgc gacacccact 1450

 ccctttaagt ccacagggga tattgcaggc acagttgtcc cagagaccaa 1500

 caaggaaccc agataccaag aggaaccccc agctcctcaa ccaaaagcag 1550

 ccccgagaac ttttcttcgt cctagtcctg aagatgaagc aatatatggc 1600

 cctaatacca aaatggtaag gttcaagaag ggagacagcg tgggcctccg 1650

 gttggctggt ggcaatgatg tcgggatatt tgttgctggc attcaagaag 1700

 ggacctcggc ggagcaggag ggccttcaag aaggagacca gattctgaag 1750

 gtgaacacac aggatttcag aggattagtg cgggaggatg ccgttctcta 1800

 cctgttagaa atccctaaag gtgaaatggt gaccatttta gctcagagcc 1850

 gagccgatgt gtatagagac atcctggctt gtggcagagg ggattcgttt 1900

 tttataagaa gccactttga atgtgagaag gaaactccac agagcctggc 1950

 cttcaccaga ggggaggtct tccgagtggt agacacactg tatgacggca 2000

 agctgggcaa ctggctggct gtgaggattg ggaacgagtt ggagaaaggc 2050

 ttaatcccca acaagagcag agctgaacaa atggccagtg ttcaaaatgc 2100

 ccagagagac aacgctgggg accgggcaga tttctggaga atgcgtggcc 2150

 agaggtctgg ggtgaagaag aacctgagga aaagtcggga agacctcaca 2200

 gctgttgtgt ctgtcagcac caagttccca gcttatgaga gggttttgct 2250

 gcgagaagct ggtttcaaga gacctgtggt cttattcggc cccatagctg 2300

 atatagcaat ggaaaaattg gctaatgagt tacctgactg gtttcaaact 2350

 gctaaaacgg aaccaaaaga tgcaggatct gagaaatcca ctggagtggt 2400

 ccggttaaat accgtgaggc aagttattga acaggataag catgcactac 2450

 tggatgtgac tccgaaagct gtggacctgt tgaattacac ccagtggttc 2500

 tcaattgtga tttctttcac gccagactcc agacaaggtg tcaacaccat 2550

 gagacaaagg ttagacccaa cgtccaacaa tagttctcga aagttatttg 2600

 atcacgccaa caagcttaaa aaaacgtgtg cacacctttt tacagctaca 2650

 atcaacctaa attcagccaa tgatagctgg tttggcagct taaaggacac 2700

 tattcagcat cagcaaggag aagcggtttg ggtctctgaa ggaaagatgg 2750

 aagggatgga tgatgacccc gaagaccgca tgtcctactt aactgccatg 2800

 ggcgcagact atctgagttg cgacagccgc ctcatcagtg actttgaaga 2850

 cacggacggt gaaggaggcg cctacactga caatgagctg gatgagccag 2900

 ccgaggagcc gctggtgtcg tccatcaccc gctcctcgga gccggtgcag 2950

 cacgaggaga gcataaggaa acccagccca gagccacgag ctcagatgag 3000

 gagggctgct agcagcgatc aacttaggga caatagcccg cccccagcat 3050

 tcaagccaga gccgtccaag gccaaaaccc agaacaaaga agaatcctat 3100

 gacttctcca aatcctatga atataagtca aacccctctg ccgttgctgg 3150

 taatgaaact cctggggcat ctaccaaagg ttatcctcct cctgttgcag 3200

 caaaacctac ctttgggcgg tctatactga agccctccac tcccatccct 3250

 cctcaagagg gtgaggaggt gggagagagc agtgaggagc aagataatgc 3300

 tcccaaatca gtcctgggca aagtcaaaat atttggagaa gatggatcac 3350

 aagggccagg gttacaagag aatgcaggag ctccaggaag cacagaatgc 3400

 aaggatcgaa attgcccaga agcatcctga tatctatgca gttccaatca 3450

 aaacgcacaa gccagaccct ggcacgcccc agcacacgag ttccagaccc 3500

 cctgagccac agaaagctcc ttccagacct tatcaggata ccagaggaag 3550

 ttatggcagt gatgccgagg aggaggagta ccgccagcag ctgtcagaac 3600

 actccaagcg cggttactat ggccagtctg cccgataccg ggacacagaa 3650

 ttatagatgt ctgagcacgg actctcccag gcctgcctgc atggcatcag 3700

 actagccact cctgccaggc cgccgggatg gttcttctcc agttagaatg 3750

 caccatggag acgtggtggg actccagctc gtgtgtcctc atggagaacc 3800

 caggggacag ctggtgcaaa ttcagaactg agggctctgt ttgtgggact 3850

 gggttagagg agtctgtggc tttttgttca gaattaagca gaacactgca 3900

 gtcagatcct gttacttgct tcagtggacc gaaatctgta ttctgtttgc 3950

 gtacttgtaa tatgtatatt aagaagcaat aactattttt cctcattaat 4000

 agctgccttc aaggactgtt tcagtgtgag tcagaatgtg aaaaaggaat 4050

 aaaaaatact gttgggctca aactaaattc aaagaagtac tttattgcaa 4100

 ctcttttaag tgccttggat gagaagtgtc ttaaattttc ttcctttgaa 4150

 gctttaggca gagccataat ggactaaaac attttgacta agtttttata 4200

 ccagcttaat agctgtagtt ttccctgcac tgtgtcatct tttcaaggca 4250

 tttgtctttg taatattttc cataaatttg gactgtctat atcataacta 4300

 tacttgatag tttggctata agtgctcaat agcttgaagc ccaagaagtt 4350

 ggtatcgaaa tttgttgttt gtttaaaccc aagtgctgca caaaagcaga 4400

 tacttgagga aaacactatt tccaaaagca catgtattga caacagtttt 4450

 ataatttaat aaaaaggaat acattgcaat ccgt 4484

<210> 531
<211> 1116
<212> PRT
<213> Homo sapien

<400> 531
 Met Pro Val Arg Gly Asp Arg Gly Phe Pro Pro Arg Arg Glu Leu
   1               5                  10                  15

 Ser Gly Trp Leu Arg Ala Pro Gly Met Glu Glu Leu Ile Trp Glu
                  20                  25                  30

 Gln Tyr Thr Val Thr Leu Gln Lys Asp Ser Lys Arg Gly Phe Gly
                  35                  40                  45

 Ile Ala Val Ser Gly Gly Arg Asp Asn Pro His Phe Glu Asn Gly
                  50                  55                  60

 Glu Thr Ser Ile Val Ile Ser Asp Val Leu Pro Gly Gly Pro Ala
                  65                  70                  75

 Asp Gly Leu Leu Gln Glu Asn Asp Arg Val Val Met Val Asn Gly
                  80                  85                  90

 Thr Pro Met Glu Asp Val Leu His Ser Phe Ala Val Gln Gln Leu
                  95                 100                 105

 Arg Lys Ser Gly Lys Val Ala Ala Ile Val Val Lys Arg Pro Arg
                 110                 115                 120

 Lys Val Gln Val Ala Ala Leu Gln Ala Ser Pro Pro Leu Asp Gln
                 125                 130                 135

 Asp Asp Arg Ala Phe Glu Val Met Asp Glu Phe Asp Gly Arg Ser
                 140                 145                 150

 Phe Arg Ser Gly Tyr Ser Glu Arg Ser Arg Leu Asn Ser His Gly
                 155                 160                 165

 Gly Arg Ser Arg Ser Trp Glu Asp Ser Pro Glu Arg Gly Arg Pro
                 170                 175                 180

 His Glu Arg Ala Arg Ser Arg Glu Arg Asp Leu Ser Arg Asp Arg
                 185                 190                 195

 Ser Arg Gly Arg Ser Leu Glu Arg Gly Leu Asp Gln Asp His Ala
                 200                 205                 210

 Arg Thr Arg Asp Arg Ser Arg Gly Arg Ser Leu Glu Arg Gly Leu
                 215                 220                 225

 Asp His Asp Phe Gly Pro Ser Arg Asp Arg Asp Arg Asp Arg Ser
                 230                 235                 240

 Arg Gly Arg Ser Ile Asp Gln Asp Tyr Glu Arg Ala Tyr His Arg
                 245                 250                 255

 Ala Tyr Asp Pro Asp Tyr Glu Arg Ala Tyr Ser Pro Glu Tyr Arg
                 260                 265                 270

 Arg Gly Ala Arg His Asp Ala Arg Ser Arg Gly Pro Arg Ser Arg
                 275                 280                 285

 Ser Arg Glu His Pro His Ser Arg Ser Pro Ser Pro Glu Pro Arg
                 290                 295                 300

 Gly Arg Pro Gly Pro Ile Gly Val Leu Leu Met Lys Ser Arg Ala
                 305                 310                 315

 Asn Glu Glu Tyr Gly Leu Arg Leu Gly Ser Gln Ile Phe Val Lys
                 320                 325                 330

 Glu Met Thr Arg Thr Gly Leu Ala Thr Lys Asp Gly Asn Leu His
                 335                 340                 345

 Glu Gly Asp Ile Ile Leu Lys Ile Asn Gly Thr Val Thr Glu Asn
                 350                 355                 360

 Met Ser Leu Thr Asp Ala Arg Lys Leu Ile Glu Lys Ser Arg Gly
                 365                 370                 375

 Lys Leu Gln Leu Val Val Leu Arg Asp Ser Gln Gln Thr Leu Ile
                 380                 385                 390

 Asn Ile Pro Ser Leu Asn Asp Ser Asp Ser Glu Ile Glu Asp Ile
                 395                 400                 405

 Ser Glu Ile Glu Ser Thr Arg Ser Phe Ser Pro Glu Glu Arg Arg
                 410                 415                 420

 His Gln Tyr Ser Asp Tyr Asp Tyr His Ser Ser Ser Glu Lys Leu
                 425                 430                 435

 Lys Glu Arg Pro Ser Ser Arg Glu Asp Thr Pro Ser Arg Leu Ser
                 440                 445                 450

 Arg Met Gly Ala Thr Pro Thr Pro Phe Lys Ser Thr Gly Asp Ile
                 455                 460                 465

 Ala Gly Thr Val Val Pro Glu Thr Asn Lys Glu Pro Arg Tyr Gln
                 470                 475                 480

 Glu Glu Pro Pro Ala Pro Gln Pro Lys Ala Ala Pro Arg Thr Phe
                 485                 490                 495

 Leu Arg Pro Ser Pro Glu Asp Glu Ala Ile Tyr Gly Pro Asn Thr
                 500                 505                 510

 Lys Met Val Arg Phe Lys Lys Gly Asp Ser Val Gly Leu Arg Leu
                 515                 520                 525

 Ala Gly Gly Asn Asp Val Gly Ile Phe Val Ala Gly Ile Gln Glu
                 530                 535                 540

 Gly Thr Ser Ala Glu Gln Glu Gly Leu Gln Glu Gly Asp Gln Ile
                 545                 550                 555

 Leu Lys Val Asn Thr Gln Asp Phe Arg Gly Leu Val Arg Glu Asp
                 560                 565                 570

 Ala Val Leu Tyr Leu Leu Glu Ile Pro Lys Gly Glu Met Val Thr
                 575                 580                 585

 Ile Leu Ala Gln Ser Arg Ala Asp Val Tyr Arg Asp Ile Leu Ala
                 590                 595                 600

 Cys Gly Arg Gly Asp Ser Phe Phe Ile Arg Ser His Phe Glu Cys
                 605                 610                 615

 Glu Lys Glu Thr Pro Gln Ser Leu Ala Phe Thr Arg Gly Glu Val
                 620                 625                 630

 Phe Arg Val Val Asp Thr Leu Tyr Asp Gly Lys Leu Gly Asn Trp
                 635                 640                 645

 Leu Ala Val Arg Ile Gly Asn Glu Leu Glu Lys Gly Leu Ile Pro
                 650                 655                 660

 Asn Lys Ser Arg Ala Glu Gln Met Ala Ser Val Gln Asn Ala Gln
                 665                 670                 675

 Arg Asp Asn Ala Gly Asp Arg Ala Asp Phe Trp Arg Met Arg Gly
                 680                 685                 690

 Gln Arg Ser Gly Val Lys Lys Asn Leu Arg Lys Ser Arg Glu Asp
                 695                 700                 705

 Leu Thr Ala Val Val Ser Val Ser Thr Lys Phe Pro Ala Tyr Glu
                 710                 715                 720

 Arg Val Leu Leu Arg Glu Ala Gly Phe Lys Arg Pro Val Val Leu
                 725                 730                 735

 Phe Gly Pro Ile Ala Asp Ile Ala Met Glu Lys Leu Ala Asn Glu
                 740                 745                 750

 Leu Pro Asp Trp Phe Gln Thr Ala Lys Thr Glu Pro Lys Asp Ala
                 755                 760                 765

 Gly Ser Glu Lys Ser Thr Gly Val Val Arg Leu Asn Thr Val Arg
                 770                 775                 780

 Gln Val Ile Glu Gln Asp Lys His Ala Leu Leu Asp Val Thr Pro
                 785                 790                 795

 Lys Ala Val Asp Leu Leu Asn Tyr Thr Gln Trp Phe Ser Ile Val
                 800                 805                 810

 Ile Ser Phe Thr Pro Asp Ser Arg Gln Gly Val Asn Thr Met Arg
                 815                 820                 825

 Gln Arg Leu Asp Pro Thr Ser Asn Asn Ser Ser Arg Lys Leu Phe
                 830                 835                 840

 Asp His Ala Asn Lys Leu Lys Lys Thr Cys Ala His Leu Phe Thr
                 845                 850                 855

 Ala Thr Ile Asn Leu Asn Ser Ala Asn Asp Ser Trp Phe Gly Ser
                 860                 865                 870

 Leu Lys Asp Thr Ile Gln His Gln Gln Gly Glu Ala Val Trp Val
                 875                 880                 885

 Ser Glu Gly Lys Met Glu Gly Met Asp Asp Asp Pro Glu Asp Arg
                 890                 895                 900

 Met Ser Tyr Leu Thr Ala Met Gly Ala Asp Tyr Leu Ser Cys Asp
                 905                 910                 915

 Ser Arg Leu Ile Ser Asp Phe Glu Asp Thr Asp Gly Glu Gly Gly
                 920                 925                 930

 Ala Tyr Thr Asp Asn Glu Leu Asp Glu Pro Ala Glu Glu Pro Leu
                 935                 940                 945

 Val Ser Ser Ile Thr Arg Ser Ser Glu Pro Val Gln His Glu Glu
                 950                 955                 960

 Ser Ile Arg Lys Pro Ser Pro Glu Pro Arg Ala Gln Met Arg Arg
                 965                 970                 975

 Ala Ala Ser Ser Asp Gln Leu Arg Asp Asn Ser Pro Pro Pro Ala
                 980                 985                 990

 Phe Lys Pro Glu Pro Ser Lys Ala Lys Thr Gln Asn Lys Glu Glu
                 995                1000                1005

 Ser Tyr Asp Phe Ser Lys Ser Tyr Glu Tyr Lys Ser Asn Pro Ser
                1010                1015                1020

 Ala Val Ala Gly Asn Glu Thr Pro Gly Ala Ser Thr Lys Gly Tyr
                1025                1030                1035

 Pro Pro Pro Val Ala Ala Lys Pro Thr Phe Gly Arg Ser Ile Leu
                1040                1045                1050

 Lys Pro Ser Thr Pro Ile Pro Pro Gln Glu Gly Glu Glu Val Gly
                1055                1060                1065

 Glu Ser Ser Glu Glu Gln Asp Asn Ala Pro Lys Ser Val Leu Gly
                1070                1075                1080

 Lys Val Lys Ile Phe Gly Glu Asp Gly Ser Gln Gly Pro Gly Leu
                1085                1090                1095

 Gln Glu Asn Ala Gly Ala Pro Gly Ser Thr Glu Cys Lys Asp Arg
                1100                1105                1110

 Asn Cys Pro Glu Ala Ser
                1115

<210> 532
<211> 2787
<212> DNA
<213> Homo sapien

<400> 532
 agagcggagg ccgcactcca gcactgcgca gggaccgcct tggaccgcag 50

 ttgccggcca ggaatcccag tgtcacggtg gacacgcctc cctcgcgccc 100

 ttgccgccca cctgctcacc cagctcaggg gctttggaat tctgtggcca 150

 cactgcgagg agatcggttc tgggtcggag gctacaggaa gactcccact 200

 ccctgaaatc tggagtgaag aacgccgcca tccagccacc attccaagga 250

 ggtgcaggag aacagctctg tgataccatt taacttgttg acattacttt 300

 tatttgaagg aacgtatatt agagcttact ttgcaaagaa ggaagatggt 350

 tgtttccgaa gtggacatcg caaaagctga tccagctgct gcatcccacc 400

 ctctattact gaatggagat gctactgtgg cccagaaaaa tccaggctcg 450

 gtggctgaga acaacctgtg cagccagtat gaggagaagg tgcgcccctg 500

 catcgacctc attgactccc tgcgggctct aggtgtggag caggacctgg 550

 ccctgccagc catcgccgtc atcggggacc agagctcggg caagagctcc 600

 gtgttggagg cactgtcagg agttgccctt cccagaggca gcgggatcgt 650

 gaccagatgc ccgctggtgc tgaaactgaa gaaacttgtg aacgaagata 700

 agtggagagg caaggtcagt taccaggact acgagattga gatttcggat 750

 gcttcagagg tagaaaagga aattaataaa gcccagaatg ccatcgccgg 800

 ggaaggaatg ggaatcagtc atgagctaat caccctggag atcagctccc 850

 gagatgtccc ggatctgact ctaatagacc ttcctggcat aaccagagtg 900

 gctgtgggca atcagcctgc tgacattggg tataagatca agacactcat 950

 caagaagtac atccagaggc aggagacaat cagcctggtg gtggtcccca 1000

 gtaatgtgga catcgccacc acagaggctc tcagcatggc ccaggaggtg 1050

 gaccccgagg gagacaggac catcggaatc ttgacgaagc ctgatctggt 1100

 ggacaaagga actgaagaca aggttgtgga cgtggtgcgg aacctcgtgt 1150

 tccacctgaa gaagggttac atgattgtca agtgccgggg ccagcaggag 1200

 atccaggacc agctgagcct gtccgaagcc ctgcagagag agaagatctt 1250

 ctttgagaac cacccatatt tcagggatct gctggaggaa ggaaaggcca 1300

 cggttccctg cctggcagaa aaacttacca gcgagctcat cacacatatc 1350

 tgtaaatctc tgcccctgtt agaaaatcaa atcaaggaga ctcaccagag 1400

 aataacagag gagctacaaa agtatggtgt cgacataccg gaagacgaaa 1450

 atgaaaaaat gttcttcctg atagataaaa ttaatgcctt taatcaggac 1500

 atcactgctc tcatgcaagg agaggaaact gtaggggagg aagacattcg 1550

 gctgtttacc agactccgac acgagttcca caaatggagt acaataattg 1600

 aaaacaattt tcaagaaggc cataaaattt tgagtagaaa aatccagaaa 1650

 tttgaaaatc agtatcgtgg tagagagctg ccaggctttg tgaattacag 1700

 gacatttgag acaatcgtga aacagcaaat caaggcactg gaagagccgg 1750

 ctgtggatat gctacacacc gtgacggata tggtccggct tgctttcaca 1800

 gatgtttcga taaaaaattt tgaagagttt tttaacctcc acagaaccgc 1850

 caagtccaaa attgaagaca ttagagcaga acaagagaga gaaggtgaga 1900

 agctgatccg cctccacttc cagatggaac agattgtcta ctgccaggac 1950

 caggtataca ggggtgcatt gcagaaggtc agagagaagg agctggaaga 2000

 agaaaagaag aagaaatcct gggattttgg ggctttccag tccagctcgg 2050

 caacagactc ttccatggag gagatctttc agcacctgat ggcctatcac 2100

 caggaggcca gcaagcgcat ctccagccac atccctttga tcatccagtt 2150

 cttcatgctc cagacgtacg gccagcagct tcagaaggcc atgctgcagc 2200

 tcctgcagga caaggacacc tacagctggc tcctgaagga gcggagcgac 2250

 accagcgaca agcggaagtt cctgaaggag cggcttgcac ggctgacgca 2300

 ggctcggcgc cggcttgccc agttccccgg ttaaccacac tctgtccagc 2350

 cccgtagacg tgcacgcaca ctgtctgccc ccgttcccgg gtagccactg 2400

 gactgacgac ttgagtgctc agtagtcaga ctggatagtc cgtctctgct 2450

 tatccgttag ccgtggtgat ttagcaggaa gctgtgagag cagtttggtt 2500

 tctagcatga agacagagcc ccaccctcag atgcacatga gctggcggga 2550

 ttgaaggatg ctgtcttcgt actgggaaag ggattttcag ccctcagaat 2600

 cgctccacct tgcagctctc cccttctctg tattcctaga aactgacaca 2650

 tgctgaacat cacagcttat ttcctcattt ttataatgtc ccttcacaaa 2700

 cccagtgttt taggagcatg agtgccgtgt gtgtgcgtcc tgtcggagcc 2750

 ctgtctcctc tctctgtaat aaactcattt ctagcag 2787

<210> 533
<211> 662
<212> PRT
<213> Homo sapien

<400> 533
 Met Val Val Ser Glu Val Asp Ile Ala Lys Ala Asp Pro Ala Ala
   1               5                  10                  15

 Ala Ser His Pro Leu Leu Leu Asn Gly Asp Ala Thr Val Ala Gln
                  20                  25                  30

 Lys Asn Pro Gly Ser Val Ala Glu Asn Asn Leu Cys Ser Gln Tyr
                  35                  40                  45

 Glu Glu Lys Val Arg Pro Cys Ile Asp Leu Ile Asp Ser Leu Arg
                  50                  55                  60

 Ala Leu Gly Val Glu Gln Asp Leu Ala Leu Pro Ala Ile Ala Val
                  65                  70                  75

 Ile Gly Asp Gln Ser Ser Gly Lys Ser Ser Val Leu Glu Ala Leu
                  80                  85                  90

 Ser Gly Val Ala Leu Pro Arg Gly Ser Gly Ile Val Thr Arg Cys
                  95                 100                 105

 Pro Leu Val Leu Lys Leu Lys Lys Leu Val Asn Glu Asp Lys Trp
                 110                 115                 120

 Arg Gly Lys Val Ser Tyr Gln Asp Tyr Glu Ile Glu Ile Ser Asp
                 125                 130                 135

 Ala Ser Glu Val Glu Lys Glu Ile Asn Lys Ala Gln Asn Ala Ile
                 140                 145                 150

 Ala Gly Glu Gly Met Gly Ile Ser His Glu Leu Ile Thr Leu Glu
                 155                 160                 165

 Ile Ser Ser Arg Asp Val Pro Asp Leu Thr Leu Ile Asp Leu Pro
                 170                 175                 180

 Gly Ile Thr Arg Val Ala Val Gly Asn Gln Pro Ala Asp Ile Gly
                 185                 190                 195

 Tyr Lys Ile Lys Thr Leu Ile Lys Lys Tyr Ile Gln Arg Gln Glu
                 200                 205                 210

 Thr Ile Ser Leu Val Val Val Pro Ser Asn Val Asp Ile Ala Thr
                 215                 220                 225

 Thr Glu Ala Leu Ser Met Ala Gln Glu Val Asp Pro Glu Gly Asp
                 230                 235                 240

 Arg Thr Ile Gly Ile Leu Thr Lys Pro Asp Leu Val Asp Lys Gly
                 245                 250                 255

 Thr Glu Asp Lys Val Val Asp Val Val Arg Asn Leu Val Phe His
                 260                 265                 270

 Leu Lys Lys Gly Tyr Met Ile Val Lys Cys Arg Gly Gln Gln Glu
                 275                 280                 285

 Ile Gln Asp Gln Leu Ser Leu Ser Glu Ala Leu Gln Arg Glu Lys
                 290                 295                 300

 Ile Phe Phe Glu Asn His Pro Tyr Phe Arg Asp Leu Leu Glu Glu
                 305                 310                 315

 Gly Lys Ala Thr Val Pro Cys Leu Ala Glu Lys Leu Thr Ser Glu
                 320                 325                 330

 Leu Ile Thr His Ile Cys Lys Ser Leu Pro Leu Leu Glu Asn Gln
                 335                 340                 345

 Ile Lys Glu Thr His Gln Arg Ile Thr Glu Glu Leu Gln Lys Tyr
                 350                 355                 360

 Gly Val Asp Ile Pro Glu Asp Glu Asn Glu Lys Met Phe Phe Leu
                 365                 370                 375

 Ile Asp Lys Ile Asn Ala Phe Asn Gln Asp Ile Thr Ala Leu Met
                 380                 385                 390

 Gln Gly Glu Glu Thr Val Gly Glu Glu Asp Ile Arg Leu Phe Thr
                 395                 400                 405

 Arg Leu Arg His Glu Phe His Lys Trp Ser Thr Ile Ile Glu Asn
                 410                 415                 420

 Asn Phe Gln Glu Gly His Lys Ile Leu Ser Arg Lys Ile Gln Lys
                 425                 430                 435

 Phe Glu Asn Gln Tyr Arg Gly Arg Glu Leu Pro Gly Phe Val Asn
                 440                 445                 450

 Tyr Arg Thr Phe Glu Thr Ile Val Lys Gln Gln Ile Lys Ala Leu
                 455                 460                 465

 Glu Glu Pro Ala Val Asp Met Leu His Thr Val Thr Asp Met Val
                 470                 475                 480

 Arg Leu Ala Phe Thr Asp Val Ser Ile Lys Asn Phe Glu Glu Phe
                 485                 490                 495

 Phe Asn Leu His Arg Thr Ala Lys Ser Lys Ile Glu Asp Ile Arg
                 500                 505                 510

 Ala Glu Gln Glu Arg Glu Gly Glu Lys Leu Ile Arg Leu His Phe
                 515                 520                 525

 Gln Met Glu Gln Ile Val Tyr Cys Gln Asp Gln Val Tyr Arg Gly
                 530                 535                 540

 Ala Leu Gln Lys Val Arg Glu Lys Glu Leu Glu Glu Glu Lys Lys
                 545                 550                 555

 Lys Lys Ser Trp Asp Phe Gly Ala Phe Gln Ser Ser Ser Ala Thr
                 560                 565                 570

 Asp Ser Ser Met Glu Glu Ile Phe Gln His Leu Met Ala Tyr His
                 575                 580                 585

 Gln Glu Ala Ser Lys Arg Ile Ser Ser His Ile Pro Leu Ile Ile
                 590                 595                 600

 Gln Phe Phe Met Leu Gln Thr Tyr Gly Gln Gln Leu Gln Lys Ala
                 605                 610                 615

 Met Leu Gln Leu Leu Gln Asp Lys Asp Thr Tyr Ser Trp Leu Leu
                 620                 625                 630

 Lys Glu Arg Ser Asp Thr Ser Asp Lys Arg Lys Phe Leu Lys Glu
                 635                 640                 645

 Arg Leu Ala Arg Leu Thr Gln Ala Arg Arg Arg Leu Ala Gln Phe
                 650                 655                 660

 Pro Gly


<210> 534
<211> 1321
<212> DNA
<213> Homo sapien

<400> 534
 cccccaagat ggctgctgag gacgagttac agctgccgcg gctccccgag 50

 ctgttcgaaa ctggtagaca gttactggac gaagtagaag tggcgactga 100

 acccgccggt tcccggatag tccaggagaa ggtgttcaag ggcttggacc 150

 tccttgagaa ggctgccgaa atgttatcgc agctcgactt gttcagccga 200

 aatgaagatt tggaagagat tgcttccacc gacctgaagt accttttggt 250

 gccagcgttt caaggagccc tcaccatgaa acaagtcaac cccagcaagc 300

 gtctagatca tttgcagcgg gctcgagaac actttataaa ctacttaact 350

 cagtgccatt gctatcatgt ggcagagttt gagctgccca aaaccatgaa 400

 caactctgct gaaaatcaca ctgccaattc ctccatggct tatcctagtc 450

 tcgttgctat ggcatctcaa agacaggcta aaatacagag atacaagcag 500

 aagaaggagt tggagcatag gttgtctgca atgaaatctg ctgtggaaag 550

 tggtcaagca gatgatgagc gtgttcgtga atattatctt cttcaccttc 600

 agaggtggat tgatatcagc ttagaagaga ttgagagcat tgaccaggaa 650

 ataaagatcc tgagagaaag agactcttca agagaggcat caacttctaa 700

 ctcatctcgc caggagaggc ctccagtgaa acccttcatt ctcactcgga 750

 acatggctca agccaaagta tttggagctg gttatccaag tctgccaact 800

 atgacggtga gtgactggta tgagcaacat cggaaatatg gagcattacc 850

 ggatcaggga atagccaagg cagcaccaga ggaattcaga aaagcagctc 900

 agcaacagga agaacaagaa gaaaaggagg aagaggatga tgaacaaaca 950

 ctccacagag cccgggagtg ggatgactgg aaggacaccc atcctagggg 1000

 ctatgggaac cgacagaaca tgggctgatc ttcccacaac accacaggac 1050

 tgcagggtgc acaactccct gccaaggaaa accatgcagt cctcccctcc 1100

 ctggtctcct gcttcagctc tgtacaacga gggcaaagat gctaaatctt 1150

 gctttgcatt cagtaaagtg tcaagtgatt aagtgtgtat ttgtacccta 1200

 gatgatatga accagcagtc ttgttttggc atcatcctca tcatgttgta 1250

 ttccagcttc ttaagtggaa ggaaaagagt gctgagaaat ggctctgtat 1300

 aatctatggc tatccgaatt c 1321

<210> 535
<211> 339
<212> PRT
<213> Homo sapien

<400> 535
 Met Ala Ala Glu Asp Glu Leu Gln Leu Pro Arg Leu Pro Glu Leu
   1               5                  10                  15

 Phe Glu Thr Gly Arg Gln Leu Leu Asp Glu Val Glu Val Ala Thr
                  20                  25                  30

 Glu Pro Ala Gly Ser Arg Ile Val Gln Glu Lys Val Phe Lys Gly
                  35                  40                  45

 Leu Asp Leu Leu Glu Lys Ala Ala Glu Met Leu Ser Gln Leu Asp
                  50                  55                  60

 Leu Phe Ser Arg Asn Glu Asp Leu Glu Glu Ile Ala Ser Thr Asp
                  65                  70                  75

 Leu Lys Tyr Leu Leu Val Pro Ala Phe Gln Gly Ala Leu Thr Met
                  80                  85                  90

 Lys Gln Val Asn Pro Ser Lys Arg Leu Asp His Leu Gln Arg Ala
                  95                 100                 105

 Arg Glu His Phe Ile Asn Tyr Leu Thr Gln Cys His Cys Tyr His
                 110                 115                 120

 Val Ala Glu Phe Glu Leu Pro Lys Thr Met Asn Asn Ser Ala Glu
                 125                 130                 135

 Asn His Thr Ala Asn Ser Ser Met Ala Tyr Pro Ser Leu Val Ala
                 140                 145                 150

 Met Ala Ser Gln Arg Gln Ala Lys Ile Gln Arg Tyr Lys Gln Lys
                 155                 160                 165

 Lys Glu Leu Glu His Arg Leu Ser Ala Met Lys Ser Ala Val Glu
                 170                 175                 180

 Ser Gly Gln Ala Asp Asp Glu Arg Val Arg Glu Tyr Tyr Leu Leu
                 185                 190                 195

 His Leu Gln Arg Trp Ile Asp Ile Ser Leu Glu Glu Ile Glu Ser
                 200                 205                 210

 Ile Asp Gln Glu Ile Lys Ile Leu Arg Glu Arg Asp Ser Ser Arg
                 215                 220                 225

 Glu Ala Ser Thr Ser Asn Ser Ser Arg Gln Glu Arg Pro Pro Val
                 230                 235                 240

 Lys Pro Phe Ile Leu Thr Arg Asn Met Ala Gln Ala Lys Val Phe
                 245                 250                 255

 Gly Ala Gly Tyr Pro Ser Leu Pro Thr Met Thr Val Ser Asp Trp
                 260                 265                 270

 Tyr Glu Gln His Arg Lys Tyr Gly Ala Leu Pro Asp Gln Gly Ile
                 275                 280                 285

 Ala Lys Ala Ala Pro Glu Glu Phe Arg Lys Ala Ala Gln Gln Gln
                 290                 295                 300

 Glu Glu Gln Glu Glu Lys Glu Glu Glu Asp Asp Glu Gln Thr Leu
                 305                 310                 315

 His Arg Ala Arg Glu Trp Asp Asp Trp Lys Asp Thr His Pro Arg
                 320                 325                 330

 Gly Tyr Gly Asn Arg Gln Asn Met Gly
                 335

<210> 536
<211> 3379
<212> DNA
<213> Homo sapien

<400> 536
 aattccgcgg aatcatcgga atccttcacc atggcatcca gcccggccca 50

 gcgtcggcga ggcaatgatc ctctcacctc cagccctggc cgaagctccc 100

 ggcgtactga tgccctcacc tccagccctg gccgtgacct tccaccattt 150

 gaggatgagt ccgaggggct cctaggcaca gaggggcccc tggaggaaga 200

 agaggatgga gaggagctca ttggagatgg catggaaagg gactaccgcg 250

 ccatcccaga gctggacgcc tatgaggccg agggactggc tctggatgat 300

 gaggacgtag aggagctgac ggccagtcga agggaggcag cagacgggcc 350

 atgcggcacg gtgaccggga gctggccggg gctgggcgca tgcgccgtgg 400

 gctcctgtat gacagcgatg aggaggacga ggagcgccct gcccgcaagc 450

 gccgccagtg gagccggcac ggaggacggc gaggaggacg agcagatgat 500

 tgagagcatc gagaacctgg aggatctcaa aggccactct gtgcgcgagt 550

 gggtgagcat ggcgggcccc cggctggaga tccaccaccg cttcaagaac 600

 ttcctgcgca ctcacgtcga cagccacggc cacaacgtct tcaaggagcg 650

 catcagcgac atgtgcaaag agaaccgtga gagcctggtg gtgaactatg 700

 aggacttggc agccagggag cacgtgctgg cctacttcct gcctgaggca 750

 ccggcggagc tgctgcagat ctttgatgag gctgccctgg aggtggtact 800

 ggccatgtac cccaagtacg accgcatcac caaccacatc catgtccgca 850

 tctcccacct gcctctggtg gaggagctgc gctcgctgag gcagctgcat 900

 ctgaaccagc tgatccgcac cagtggggtg gtgaccagct gcactggcgt 950

 cctgccccag ctcagcatgg tcaagtacaa ctgcaacaag tgcaatttcg 1000

 tcctgggtcc tttctgccag tcccagaacc aggaggtgaa accaggctcc 1050

 tgtcctgagt gccagtcggc cggccccttt gaggtcaaca tggaggagac 1100

 catctatcag aactaccagc gtatccgaat ccaggagagt ccaggcaaag 1150

 tggcggctcg gcggctgccc cgctccaagg acgccattct cctcgcagat 1200

 ctggtggaca gctgcaacgc aggagacgag atagagctga ctggcatcta 1250

 tcacaacaac tatgatggct ccctcaacac tgccaatggc ttccctgtct 1300

 ttgccactgt catcctagcc aaccacgtgg ccaagaagga caacaaggtt 1350

 gctgtagggg aactgaccga tgaagatgtg aagatgatca ctagcctctc 1400

 caaggatcag cagatcggag agaagatctt tgccagcatt gctccttcca 1450

 tctatggtca tgaagacatc aagagaggcc ctgctctggc cctgttcgga 1500

 ggggagccca aaaacccagg tggcaagcac aaggtacgtg gtgatatcaa 1550

 cgtgctcttg tgcggagacc ctggcacagc gaagtcgcag tttctcaagt 1600

 atattgagaa agtgtccagc cgagccatct tcaccactgg ccagggggcg 1650

 tcggctgtgg ccgtcacggc gtatgtccag cggcaccctg tcagcaggga 1700

 gtggaccttg gaggctgggg ccctggttct ggctgaccga ggagtgtgtc 1750

 tcattgatga atttgacaag atgaatgacc aggacagaac cagcatccat 1800

 gaggccatgg agcaacagag catctccatc tcgaaggctg gcatcgtcac 1850

 ctccctgcag gctcgctgca cggtcattgc tgccgccaac cccataggag 1900

 ggcgctacga cccctcgctg actttctctg agaacgtgga cctcacagag 1950

 cccatcatct cacgctttga catcctgtgt gtggtgaggg acaccgtgga 2000

 cccagtccag gacgagatgc tggcccgctt cgtggtgggc agccacgtca 2050

 gacaccaccc cagcaacaag gaggaggagg ggctggccaa tggcagcgct 2100

 gctgagcccg ccatgcccaa cacgtatggc gtggagcccc tgccccagga 2150

 ggtcctgaag aagtacatca tctacgccaa ggagagggtc cacccgaagc 2200

 tcaaccagat ggaccaggac aaggtggcca agatgtacag tgacctgagg 2250

 aaagaatcta tggcgacagg cagcatcccc attacggtgc ggcacatcga 2300

 gtccatgagt catggcggag gcccacgcgc gcatccatct gcgggactat 2350

 gtgatcgaag acgacgtcaa catggccatc cgcgtgatgc tggagagctt 2400

 catagacaca cagaagttca gcgtcatcgc agcatgcgca agacttttgc 2450

 ccgctacctt tcattccggc gtgacaacaa tgagctgttg ctcttcatac 2500

 tgaagcagtt agtggcagag caggtgacat atcagcgcaa ccgctttggg 2550

 gcccagcagg acactattga ggtccctgag aaggacttgg tggataaggc 2600

 tcgtcagatc aacatccaca acctctctgc attttatgac agtgagctct 2650

 tcaggatgaa caagttcagc cacgacctga aaaggaaaat gatcctgcag 2700

 cagttctgag gccctatgcc atccataagg attccttggg attctggttt 2750

 ggggtggtca gtgccctctg tgctttatgg acacaaaacc agagcacttg 2800

 atgaactcgg ggtactaggg tcagggctta tagcaggatg tctggctgca 2850

 cctggcatga ctgtttgttt ctccaagcct gctttgtgct tctcaccttt 2900

 gggtgggatg ccttgccagt gtgtcttact tggttgctga acatcttgcc 2950

 acctccgagt gctttgtctc cactcagtac cttggatcag agctgctgag 3000

 ttcaggatgc ctgcgtgtgg tttaggtgtt agccttctta catggatgtc 3050

 aggagagctg ctgccctctt ggcgtgagtt gcgtattcag gctgcttttg 3100

 ctcgctttgg ccagagagct ggttgaagat gtttgtaatc gttttcagtc 3150

 tcctgcaggt ttctgtgccc ctgtggtgga agaggcacga cagtgccagc 3200

 gcagcgttct gggctcctca gtcgcagggg tgggatgtga gtcatgcgga 3250

 ttatccactc gccacagtta tcagctgcca ttgctccctg tctgtttccc 3300

 cactctctta tttgtgcatt cggtttggtt tctgtagttt taatttttaa 3350

 taaagttgaa taaaatataa aaaaaaaaa 3379

<210> 537
<211> 892
<212> PRT
<213> Homo sapien

<400> 537
 Met Ala Ser Ser Pro Ala Gln Arg Arg Arg Gly Asn Asp Pro Leu
   1               5                  10                  15

 Thr Ser Ser Pro Gly Arg Ser Ser Arg Arg Thr Asp Ala Leu Thr
                  20                  25                  30

 Ser Ser Pro Gly Arg Asp Leu Pro Pro Phe Glu Asp Glu Ser Glu
                  35                  40                  45

 Gly Leu Leu Gly Thr Glu Gly Pro Leu Glu Glu Glu Glu Asp Gly
                  50                  55                  60

 Glu Glu Leu Ile Gly Asp Gly Met Glu Arg Asp Tyr Arg Ala Ile
                  65                  70                  75

 Pro Glu Leu Asp Ala Tyr Glu Ala Glu Gly Leu Ala Leu Asp Asp
                  80                  85                  90

 Glu Asp Val Glu Glu Leu Thr Ala Ser Arg Arg Glu Ala Ala Asp
                  95                 100                 105

 Gly Pro Cys Gly Thr Val Thr Gly Ser Trp Pro Gly Leu Gly Ala
                 110                 115                 120

 Cys Ala Val Gly Ser Cys Met Thr Ala Met Arg Arg Thr Arg Ser
                 125                 130                 135

 Ala Leu Pro Ala Ser Ala Ala Ser Gly Ala Gly Thr Glu Asp Gly
                 140                 145                 150

 Glu Glu Asp Glu Gln Met Ile Glu Ser Ile Glu Asn Leu Glu Asp
                 155                 160                 165

 Leu Lys Gly His Ser Val Arg Glu Trp Val Ser Met Ala Gly Pro
                 170                 175                 180

 Arg Leu Glu Ile His His Arg Phe Lys Asn Phe Leu Arg Thr His
                 185                 190                 195

 Val Asp Ser His Gly His Asn Val Phe Lys Glu Arg Ile Ser Asp
                 200                 205                 210

 Met Cys Lys Glu Asn Arg Glu Ser Leu Val Val Asn Tyr Glu Asp
                 215                 220                 225

 Leu Ala Ala Arg Glu His Val Leu Ala Tyr Phe Leu Pro Glu Ala
                 230                 235                 240

 Pro Ala Glu Leu Leu Gln Ile Phe Asp Glu Ala Ala Leu Glu Val
                 245                 250                 255

 Val Leu Ala Met Tyr Pro Lys Tyr Asp Arg Ile Thr Asn His Ile
                 260                 265                 270

 His Val Arg Ile Ser His Leu Pro Leu Val Glu Glu Leu Arg Ser
                 275                 280                 285

 Leu Arg Gln Leu His Leu Asn Gln Leu Ile Arg Thr Ser Gly Val
                 290                 295                 300

 Val Thr Ser Cys Thr Gly Val Leu Pro Gln Leu Ser Met Val Lys
                 305                 310                 315

 Tyr Asn Cys Asn Lys Cys Asn Phe Val Leu Gly Pro Phe Cys Gln
                 320                 325                 330

 Ser Gln Asn Gln Glu Val Lys Pro Gly Ser Cys Pro Glu Cys Gln
                 335                 340                 345

 Ser Ala Gly Pro Phe Glu Val Asn Met Glu Glu Thr Ile Tyr Gln
                 350                 355                 360

 Asn Tyr Gln Arg Ile Arg Ile Gln Glu Ser Pro Gly Lys Val Ala
                 365                 370                 375

 Ala Arg Arg Leu Pro Arg Ser Lys Asp Ala Ile Leu Leu Ala Asp
                 380                 385                 390

 Leu Val Asp Ser Cys Asn Ala Gly Asp Glu Ile Glu Leu Thr Gly
                 395                 400                 405

 Ile Tyr His Asn Asn Tyr Asp Gly Ser Leu Asn Thr Ala Asn Gly
                 410                 415                 420

 Phe Pro Val Phe Ala Thr Val Ile Leu Ala Asn His Val Ala Lys
                 425                 430                 435

 Lys Asp Asn Lys Val Ala Val Gly Glu Leu Thr Asp Glu Asp Val
                 440                 445                 450

 Lys Met Ile Thr Ser Leu Ser Lys Asp Gln Gln Ile Gly Glu Lys
                 455                 460                 465

 Ile Phe Ala Ser Ile Ala Pro Ser Ile Tyr Gly His Glu Asp Ile
                 470                 475                 480

 Lys Arg Gly Pro Ala Leu Ala Leu Phe Gly Gly Glu Pro Lys Asn
                 485                 490                 495

 Pro Gly Gly Lys His Lys Val Arg Gly Asp Ile Asn Val Leu Leu
                 500                 505                 510

 Cys Gly Asp Pro Gly Thr Ala Lys Ser Gln Phe Leu Lys Tyr Ile
                 515                 520                 525

 Glu Lys Val Ser Ser Arg Ala Ile Phe Thr Thr Gly Gln Gly Ala
                 530                 535                 540

 Ser Ala Val Ala Val Thr Ala Tyr Val Gln Arg His Pro Val Ser
                 545                 550                 555

 Arg Glu Trp Thr Leu Glu Ala Gly Ala Leu Val Leu Ala Asp Arg
                 560                 565                 570

 Gly Val Cys Leu Ile Asp Glu Phe Asp Lys Met Asn Asp Gln Asp
                 575                 580                 585

 Arg Thr Ser Ile His Glu Ala Met Glu Gln Gln Ser Ile Ser Ile
                 590                 595                 600

 Ser Lys Ala Gly Ile Val Thr Ser Leu Gln Ala Arg Cys Thr Val
                 605                 610                 615

 Ile Ala Ala Ala Asn Pro Ile Gly Gly Arg Tyr Asp Pro Ser Leu
                 620                 625                 630

 Thr Phe Ser Glu Asn Val Asp Leu Thr Glu Pro Ile Ile Ser Arg
                 635                 640                 645

 Phe Asp Ile Leu Cys Val Val Arg Asp Thr Val Asp Pro Val Gln
                 650                 655                 660

 Asp Glu Met Leu Ala Arg Phe Val Val Gly Ser His Val Arg His
                 665                 670                 675

 His Pro Ser Asn Lys Glu Glu Glu Gly Leu Ala Asn Gly Ser Ala
                 680                 685                 690

 Ala Glu Pro Ala Met Pro Asn Thr Tyr Gly Val Glu Pro Leu Pro
                 695                 700                 705

 Gln Glu Val Leu Lys Lys Tyr Ile Ile Tyr Ala Lys Glu Arg Val
                 710                 715                 720

 His Pro Lys Leu Asn Gln Met Asp Gln Asp Lys Val Ala Lys Met
                 725                 730                 735

 Tyr Ser Asp Leu Arg Lys Glu Ser Met Ala Thr Gly Ser Ile Pro
                 740                 745                 750

 Ile Thr Val Arg His Ile Glu Ser Met Ser His Gly Gly Gly Pro
                 755                 760                 765

 Arg Ala His Pro Ser Ala Gly Leu Cys Asp Arg Arg Arg Arg Gln
                 770                 775                 780

 His Gly His Pro Arg Asp Ala Gly Glu Leu His Arg His Thr Glu
                 785                 790                 795

 Val Gln Arg His Arg Ser Met Arg Lys Thr Phe Ala Arg Tyr Leu
                 800                 805                 810

 Ser Phe Arg Arg Asp Asn Asn Glu Leu Leu Leu Phe Ile Leu Lys
                 815                 820                 825

 Gln Leu Val Ala Glu Gln Val Thr Tyr Gln Arg Asn Arg Phe Gly
                 830                 835                 840

 Ala Gln Gln Asp Thr Ile Glu Val Pro Glu Lys Asp Leu Val Asp
                 845                 850                 855

 Lys Ala Arg Gln Ile Asn Ile His Asn Leu Ser Ala Phe Tyr Asp
                 860                 865                 870

 Ser Glu Leu Phe Arg Met Asn Lys Phe Ser His Asp Leu Lys Arg
                 875                 880                 885

 Lys Met Ile Leu Gln Gln Phe
                 890

<210> 538
<211> 3497
<212> DNA
<213> Homo sapien

<400> 538
 cggacgcggc cgccgccgtc gccgccatct gtcacctcca ctccggcatc 50

 agcagccagt cgcccgtgtc ccgcctgtct cctcggcgga gcctgctgcc 100

 cgtcctgcca cctctctgct ctgttcttgt ctctgccttc attcccgaat 150

 ggatctggta ggagtggcat cgcctgagcc cgggacggca gcggcctggg 200

 gacccagcaa gtgtccatgg gctattcctc aaaatacaat atcttgttct 250

 ttggctgatg taatgagtga acagctggcc aaagaattgc agttagaaga 300

 agaagctgcc gtttttcctg aagttgctgt tgctgaagga ccatttatta 350

 ctggagaaaa cattgatact tccagtgacc ttatgctggc tcagatgcta 400

 cagatggaat atgacagaga atatgatgca cagcttaggc gtgaagaaaa 450

 aaaattcaat ggagatagca aagtttccat ttcctttgaa aattatcgaa 500

 aagtgcatcc ttatgaagac agcgatagct ctgaagatga ggttgactgg 550

 caggatactc gtgatgatcc ctacagacca gcaaaaccgg ttcccactcc 600

 taaaaagggc tttattggaa aaggaaaaga tatcaccacc aaacatgatg 650

 aagtagtatg tgggagaaag aacacagcaa gaatggaaaa ttttgcacct 700

 gagtttcagg taggagatgg aattggaatg gatttaaaac tatcaaacca 750

 tgttttcaat gctttaaaac aacatgccta ctcagaagaa cgtcgaagtg 800

 cccgcctaca tgagaaaaag gagcattcta cagcagaaaa agcagttgat 850

 cctaagacac gtttacttat gtataaaatg gtcaactctg gaatgttgga 900

 gacaatcact ggctgtatta gtacaggaaa ggagtctgtt gtctttcatg 950

 catatggagg gagcatggag gatgaaaagg aagatagtaa agttatacct 1000

 acagaatgtg ccatcaaggt atttaaaaca acccttaatg aatttaagaa 1050

 tcgtgacaaa tatattaaag atgatttcag gtttaaagat cgcttcagta 1100

 aactaaatcc acgtaagatc atccgcatgt gggcagaaaa agaaatgcac 1150

 aatctcgcaa gaatgcagag agctggaatt ccttgtccaa cagttgtact 1200

 actgaagaaa cacattttag ttatgtcttt tattggccat gatcaagttc 1250

 cagcccctaa attaaaagaa gtaaagctca atagtgaaga aatgaaagaa 1300

 gcctactatc aaactcttca tttgatgcgg cagttatatc atgaatgtac 1350

 gcttgtccat gctgacctca gtgagtataa catgctgtgg catgctggaa 1400

 aggtctggtt gatcgatgtc agtcagtcag tagaacctac ccaccctcac 1450

 ggcctggagt tcttgttccg ggactgcagg aatgtctcgc agtttttcca 1500

 gaaaggagga gtcaaggaag cccttagtga acgagaactc ttcaatgctg 1550

 tttcaggctt aaacatcaca gcagataatg aagctgattt tttagctgag 1600

 atagaagctt tggagaaaat gaatgaagat cacgttcaga agaatggaag 1650

 gaaagctgct tcatttttga aagatgatgg agacccacca ctactatatg 1700

 atgaatagca ctaataccca ctgcttcagt gttaacacag cagtgattgt 1750

 cagctgccaa tagcaaatga agttatgggt gacttgaaat accaaaacct 1800

 gaggagtggg caatggtgct tctgtgcttt tcccccttgt aacccatgtg 1850

 ccagatgtgt ggaattttta gctcagcatt gagagaataa aatgtcacta 1900

 cctctcatct tatgaacagg ataatataat tctttaacag ctataggtta 1950

 tctggctgaa gtagacctaa ttttatgtga cttgtggtgt aaaatgtctt 2000

 gatgataatt tttaaaactt gggtaacact tccaaatatg ggaggaaagg 2050

 acagatgtgt ttacaaggga ggattttaca acatacttgc tttattcacc 2100

 tccctgtttt gtgttgcgtc tttccttgaa tattttattg gcccagagtt 2150

 agcctttctc aattatgttt ccagactgtg gccgtgattc taaaggaaaa 2200

 tgtgtgctct ttagtgggta gaacaaatgg aaatttggtt tcagaatggc 2250

 tgacagaaat cgacataagt catgtaattt ttgttgatat atcatgaaaa 2300

 tgaacagaat tctttttcca tacttatatc taagaaaagg catcataggt 2350

 ttctgaaaga gataactata taacagcttt ttaactatcc agtcaacttt 2400

 cagcttttct acatttaggt aaaatggtta ggatataact catggtgtgg 2450

 ctaatctaca tttatcaata aaatgtaaat tatctgaaag gacagaatat 2500

 aagatttaac catgtttgac gtattttaat ttagttaatg aagcaaaatt 2550

 cagtttatat ttcactagaa ctgtgtactt gattgatttt cagagaaata 2600

 tcacaaatta gaaatattaa atctaaggat gaaaggtata tataaaacaa 2650

 tttgggggcc aggcacgatg gctcaaacct gtaatcccag cactttggga 2700

 gaccaaggcg ggtggatcac ttgaggtcag gagttcaaga ccagcctggg 2750

 caacatggcg aaaccctgtc tctactaaaa atacaaaaat tagccgggtg 2800

 tggtggcact tctctgtaat ctcagcttct caggaggctg agacaggaga 2850

 atcgcttgaa cccgggaggc agaggttgca gtgagctgag atcatgccac 2900

 tgcactccgg cctaggtgac agagggaaac tccatctcca ggaaaaaaaa 2950

 aaaaaaaccc aatttggata ccaaattaat caactaattt gagctatctg 3000

 gccttactct tagtagtttt tagtacgtgc tggacaccac ttttaaaaag 3050

 caatcactgt gctagaaaag tatattggct ttgttaggat taaagttcat 3100

 taacttcaat gtaatcatgc ctcctattac tgaagtcaga ttggaaccac 3150

 taaagatcca aactttctgt ctggtaatag aaagtaaaaa tctagacatc 3200

 atttacattt gagaagctgt ttttaacatt attttaaaat gccaaatatg 3250

 ttctttctag aaaaatattt atttttgttt ttgttggata gcttttaatt 3300

 acatttcaga gaggtgtaat tttgggtaga tgctcattac atttttgaaa 3350

 ggtttatgat tccaaaataa agatttatat gactggtgat actggcttta 3400

 cagaaatttc agagaactaa tttttaaaat ctttagcatt taaaactttt 3450

 tttgttttgt tttctgacat attctgacaa agagcagcaa accactg 3497

<210> 539
<211> 519
<212> PRT
<213> Homo sapien

<400> 539
 Met Asp Leu Val Gly Val Ala Ser Pro Glu Pro Gly Thr Ala Ala
   1               5                  10                  15

 Ala Trp Gly Pro Ser Lys Cys Pro Trp Ala Ile Pro Gln Asn Thr
                  20                  25                  30

 Ile Ser Cys Ser Leu Ala Asp Val Met Ser Glu Gln Leu Ala Lys
                  35                  40                  45

 Glu Leu Gln Leu Glu Glu Glu Ala Ala Val Phe Pro Glu Val Ala
                  50                  55                  60

 Val Ala Glu Gly Pro Phe Ile Thr Gly Glu Asn Ile Asp Thr Ser
                  65                  70                  75

 Ser Asp Leu Met Leu Ala Gln Met Leu Gln Met Glu Tyr Asp Arg
                  80                  85                  90

 Glu Tyr Asp Ala Gln Leu Arg Arg Glu Glu Lys Lys Phe Asn Gly
                  95                 100                 105

 Asp Ser Lys Val Ser Ile Ser Phe Glu Asn Tyr Arg Lys Val His
                 110                 115                 120

 Pro Tyr Glu Asp Ser Asp Ser Ser Glu Asp Glu Val Asp Trp Gln
                 125                 130                 135

 Asp Thr Arg Asp Asp Pro Tyr Arg Pro Ala Lys Pro Val Pro Thr
                 140                 145                 150

 Pro Lys Lys Gly Phe Ile Gly Lys Gly Lys Asp Ile Thr Thr Lys
                 155                 160                 165

 His Asp Glu Val Val Cys Gly Arg Lys Asn Thr Ala Arg Met Glu
                 170                 175                 180

 Asn Phe Ala Pro Glu Phe Gln Val Gly Asp Gly Ile Gly Met Asp
                 185                 190                 195

 Leu Lys Leu Ser Asn His Val Phe Asn Ala Leu Lys Gln His Ala
                 200                 205                 210

 Tyr Ser Glu Glu Arg Arg Ser Ala Arg Leu His Glu Lys Lys Glu
                 215                 220                 225

 His Ser Thr Ala Glu Lys Ala Val Asp Pro Lys Thr Arg Leu Leu
                 230                 235                 240

 Met Tyr Lys Met Val Asn Ser Gly Met Leu Glu Thr Ile Thr Gly
                 245                 250                 255

 Cys Ile Ser Thr Gly Lys Glu Ser Val Val Phe His Ala Tyr Gly
                 260                 265                 270

 Gly Ser Met Glu Asp Glu Lys Glu Asp Ser Lys Val Ile Pro Thr
                 275                 280                 285

 Glu Cys Ala Ile Lys Val Phe Lys Thr Thr Leu Asn Glu Phe Lys
                 290                 295                 300

 Asn Arg Asp Lys Tyr Ile Lys Asp Asp Phe Arg Phe Lys Asp Arg
                 305                 310                 315

 Phe Ser Lys Leu Asn Pro Arg Lys Ile Ile Arg Met Trp Ala Glu
                 320                 325                 330

 Lys Glu Met His Asn Leu Ala Arg Met Gln Arg Ala Gly Ile Pro
                 335                 340                 345

 Cys Pro Thr Val Val Leu Leu Lys Lys His Ile Leu Val Met Ser
                 350                 355                 360

 Phe Ile Gly His Asp Gln Val Pro Ala Pro Lys Leu Lys Glu Val
                 365                 370                 375

 Lys Leu Asn Ser Glu Glu Met Lys Glu Ala Tyr Tyr Gln Thr Leu
                 380                 385                 390

 His Leu Met Arg Gln Leu Tyr His Glu Cys Thr Leu Val His Ala
                 395                 400                 405

 Asp Leu Ser Glu Tyr Asn Met Leu Trp His Ala Gly Lys Val Trp
                 410                 415                 420

 Leu Ile Asp Val Ser Gln Ser Val Glu Pro Thr His Pro His Gly
                 425                 430                 435

 Leu Glu Phe Leu Phe Arg Asp Cys Arg Asn Val Ser Gln Phe Phe
                 440                 445                 450

 Gln Lys Gly Gly Val Lys Glu Ala Leu Ser Glu Arg Glu Leu Phe
                 455                 460                 465

 Asn Ala Val Ser Gly Leu Asn Ile Thr Ala Asp Asn Glu Ala Asp
                 470                 475                 480

 Phe Leu Ala Glu Ile Glu Ala Leu Glu Lys Met Asn Glu Asp His
                 485                 490                 495

 Val Gln Lys Asn Gly Arg Lys Ala Ala Ser Phe Leu Lys Asp Asp
                 500                 505                 510

 Gly Asp Pro Pro Leu Leu Tyr Asp Glu
                 515

<210> 540
<211> 1221
<212> DNA
<213> Homo sapien

<400> 540
 ccgaacgccc gcagcagggt cagaagggag gtggccggtc tccgtcgtga 50

 cctctgacgg tttctgagcg ttggcctttg gcacgcgcta cacccttttg 100

 ctttggttct gccatgccga tgtaccaggt aaagccctat cacgggggcg 150

 gcgcgcctct ccgtgtggag cttcccacct gcatgtaccg gctccccaac 200

 gtgcacggca ggagctacgg cccagcgccg ggcgctggcc acgtgcagga 250

 agagtctaac ctgtctctgc aagctcttga gtcccgccaa gatgatattt 300

 taaaacgtct gtatgagttg aaagctgcag ttgatggcct ctccaagatg 350

 attcaaacac cagatgcaga cttggatgta accaacataa tccaagcgga 400

 tgagcccacg actttaacca ccaatgcgct ggacttgaat tcagtgcttg 450

 ggaaggatta cggggcgctg aaagacatcg tgatcaacgc aaacccggcc 500

 tcccctcccc tctccctgct tgtgctgcac aggctgctct gtgagcactt 550

 cagggtcctg tccacggtgc acacgcactc ctcggtcaag agcgtgcctg 600

 aaaaccttct caagtgcttt ggagaacaga ataaaaaaca gccccgccaa 650

 gactatcagc tgggattcac tttaatttgg aagaatgtgc cgaagacgca 700

 gatgaaattc agcatccaga cgatgtgccc catcgaaggc gaagggaaca 750

 ttgcacgttt cttgttctct ctgtttggcc agaagcataa tgctgtcaac 800

 gcaaccctta tagatagctg ggtagatatt gcgatttttc agttaaaaga 850

 gggaagcagt aaagaaaaag ccgctgtttt ccgctccatg aactctgctc 900

 ttgggaagag cccttggctc gctgggaatg aactcaccgt agcagacgtg 950

 gtgctgtggt ctgtactcca gcagatcgga ggctgcagtg tgacagtgcc 1000

 agccaatgtg cagaggtgga tgaggtcttg tgaaaacctg gctcctttta 1050

 acacggccct caagctcctt aagtgaattg ccgtaactga ttttaaaggg 1100

 tttagatttt aagaatggtg ctctttcatg cctattatca gtaaggggac 1150

 ttgtattaga gtcagagtct ttttatttag gccagttgtc aagtgtcaat 1200

 aaaagcgcat catgtaattt a 1221

<210> 541
<211> 320
<212> PRT
<213> Homo sapien

<400> 541
 Met Pro Met Tyr Gln Val Lys Pro Tyr His Gly Gly Gly Ala Pro
   1               5                  10                  15

 Leu Arg Val Glu Leu Pro Thr Cys Met Tyr Arg Leu Pro Asn Val
                  20                  25                  30

 His Gly Arg Ser Tyr Gly Pro Ala Pro Gly Ala Gly His Val Gln
                  35                  40                  45

 Glu Glu Ser Asn Leu Ser Leu Gln Ala Leu Glu Ser Arg Gln Asp
                  50                  55                  60

 Asp Ile Leu Lys Arg Leu Tyr Glu Leu Lys Ala Ala Val Asp Gly
                  65                  70                  75

 Leu Ser Lys Met Ile Gln Thr Pro Asp Ala Asp Leu Asp Val Thr
                  80                  85                  90

 Asn Ile Ile Gln Ala Asp Glu Pro Thr Thr Leu Thr Thr Asn Ala
                  95                 100                 105

 Leu Asp Leu Asn Ser Val Leu Gly Lys Asp Tyr Gly Ala Leu Lys
                 110                 115                 120

 Asp Ile Val Ile Asn Ala Asn Pro Ala Ser Pro Pro Leu Ser Leu
                 125                 130                 135

 Leu Val Leu His Arg Leu Leu Cys Glu His Phe Arg Val Leu Ser
                 140                 145                 150

 Thr Val His Thr His Ser Ser Val Lys Ser Val Pro Glu Asn Leu
                 155                 160                 165

 Leu Lys Cys Phe Gly Glu Gln Asn Lys Lys Gln Pro Arg Gln Asp
                 170                 175                 180

 Tyr Gln Leu Gly Phe Thr Leu Ile Trp Lys Asn Val Pro Lys Thr
                 185                 190                 195

 Gln Met Lys Phe Ser Ile Gln Thr Met Cys Pro Ile Glu Gly Glu
                 200                 205                 210

 Gly Asn Ile Ala Arg Phe Leu Phe Ser Leu Phe Gly Gln Lys His
                 215                 220                 225

 Asn Ala Val Asn Ala Thr Leu Ile Asp Ser Trp Val Asp Ile Ala
                 230                 235                 240

 Ile Phe Gln Leu Lys Glu Gly Ser Ser Lys Glu Lys Ala Ala Val
                 245                 250                 255

 Phe Arg Ser Met Asn Ser Ala Leu Gly Lys Ser Pro Trp Leu Ala
                 260                 265                 270

 Gly Asn Glu Leu Thr Val Ala Asp Val Val Leu Trp Ser Val Leu
                 275                 280                 285

 Gln Gln Ile Gly Gly Cys Ser Val Thr Val Pro Ala Asn Val Gln
                 290                 295                 300

 Arg Trp Met Arg Ser Cys Glu Asn Leu Ala Pro Phe Asn Thr Ala
                 305                 310                 315

 Leu Lys Leu Leu Lys
                 320

<210> 542
<211> 3635
<212> DNA
<213> Homo sapien

<400> 542
 gtttcttcag actccagatt tccctgtcaa ccacgaggag tccagagagg 50

 aaacgcggag cggagacaac agtacctgac gcctctttca gcccgggatc 100

 gccccagcag ggatgggcga caagatctgg ctgcccttcc ccgtgctcct 150

 tctggccgct ctgcctccgg tgctgctgcc tggggcggcc ggcttcacac 200

 cttccctcga tagcgacttc acctttaccc ttcccgccgg ccagaaggag 250

 tgcttctacc agcccatgcc cctgaaggcc tcgctggaga tcgagtacca 300

 agttttagat ggagcaggat tagatattga tttccatctt gcctctccag 350

 aaggcaaaac cttagttttt gaacaaagaa aatcagatgg agttcacact 400

 gtagagactg aagttggtga ttacatgttc tgctttgaca atacattcag 450

 caccatttct gagaaggtga ttttctttga attaatcctg gataatatgg 500

 gagaacaggc acaagaacaa gaagattgga agaaatatat tactggcaca 550

 gatatattgg atatgaaact ggaagacatc ctggaatcca tcaacagcat 600

 caagtccaga ctaagcaaaa gtgggcacat acaaattctg cttagagcat 650

 ttgaagctcg tgatcgaaac atacaagaaa gcaactttga tagagtcaat 700

 ttctggtcta tggttaattt agtggtcatg gtggtggtgt cagccattca 750

 agtttatatg ctgaagagtc tgtttgaaga taagaggaaa agtagaactt 800

 aaaactccaa actagagtac gtaacattga aaaatgaggc ataaaaatgc 850

 aataaactgt tacagtcaag accattaatg gtcttctcca aaatattttg 900

 agatataaaa gtaggaaaca ggtataattt taatgtgaaa attaagtctt 950

 cactttctgt gcaagtaatc ctgctgatcc agttgtactt aagtgtgtaa 1000

 caggaatatt ttgcagaata taggtttaac tgaatgaagc catattaata 1050

 actgcatttt cctaactttg aaaaattttg caaatgtctt aggtgattta 1100

 aataaatgag tattgggcct aattgcaaca ccagtctgtt tttaacaggt 1150

 tctattaccc agaacttttt tgtaaatgcg gcagttacaa attaactgtg 1200

 gaagttttca gttttaagtt ataaatcacc tgagaattac ctaatgatgg 1250

 attgaataaa tctttagact acaaaagccc aacttttctc tatttacata 1300

 tgcatctctc ctataatgta aatagaataa tagctttgaa atacaattag 1350

 gtttttgaga tttttataac caaatacatt tcagtgtaac atattagcag 1400

 aaagcattag tctttgtact ttgcttacat tcccaaaagc tgacattttc 1450

 acgattctta aaaacacaaa gttacactta ctaaaattag gacatgtttt 1500

 ctctttgaaa tgaagaatat agtttaaaag cttcctcctc catagggaca 1550

 cattttctct aacccttaac taaagtgtag gattttaaaa ttaaatgtga 1600

 ggtaaaataa gtttattttt aatagtatct gtcaagttaa tatctgtcaa 1650

 cagttaataa tcatgttatg ttaattttaa catgattgct gacttggata 1700

 attcattatt accagcagtt atgaaggaaa tattgctaaa atgatctggg 1750

 cctaccataa ataaatatct ccttttctga gctctaagaa ttatcagaaa 1800

 caggaaagaa tttagaaaaa cttgagaaaa cctaatccaa aataaaattc 1850

 acttaagtag aactataaat aaatatctag aatctgactg gctcatcatg 1900

 acatcctact cataacataa atcaaaggag atgattaatt tccagttagc 1950

 tggaagaaac tttggctgta ggtttttatt ttctacaaga attctggttt 2000

 gaattatttt tgtaagcagg tacattttat aaaatgtaag ccctactgta 2050

 aggtttagca ctgggtgtac atatttatta aaaattttta ttataacaac 2100

 ttttattaaa atggcctttc tgaacacttt atttattgat gttgaagtaa 2150

 ggattagaaa catagactcc caagttttaa acacctaaat gtgaataacc 2200

 catatataca acaaagtttc tgccatctag ctttttgaag tctatggggg 2250

 tcttactcaa gtactagtaa tttaacttca tcatgaatga actataattt 2300

 ttaagttatg cccatttata acgttgttta tgactacatt gtgagttaga 2350

 aacaaactta aaatttgggg tatagaaccc ctcaacaggt tagtaatgct 2400

 ggaattcttg atgagcaata atgataacca gagagtgatt tcatttacac 2450

 tcatagtagt ataaaaagag atacatttcc ctcttaggcc cctgggagaa 2500

 gagcagctta gatttcccta ctggcaaggt ttttaaaaat gaggtaaatg 2550

 ccgtatatga tcaattacct taattggcca agaaaatgct tcaggtgtct 2600

 aggggtatcc tctgcaacac ttgcagaaca aaggtcaata agatccttgc 2650

 ctatgaatac ccctcccttt tgcgctgtta aatttgcaat gagaagcaaa 2700

 tttacagtac cataactaat aaagcagggt acagatataa actactgcat 2750

 cttttctata aaactgtgat taagaattct acctctcctg tatggctgtt 2800

 actgtactgt actctctgac tccttaccta acaatgaatt tgttacataa 2850

 tcttctacat gtatgatttg tgccactgat cttaaaccta tgattcagta 2900

 acttcttacc atataaaaac gataattgct ttatttggaa aagaatttag 2950

 gaatactaag gacaattatt tttatagaca aagtaaaaag acagatattt 3000

 aagaggcata accaaaaaag caaaacttgt aaacagagta aaaatcttta 3050

 atatttctaa agacatactg tttatctgct tcatatgctt tttttaattt 3100

 cactattcca tttctaaatt aaagttatgc taaattgagt aagctgttta 3150

 tcacttaaca gctcattttg tctttttcaa tatacaaatt ttaaaaatac 3200

 tacaatattt aactaaggcc caaccgattt ccataatgta gcagttaccg 3250

 tgttcacctc acactaaggc ctagagtttg ctctgatatg catttggatg 3300

 attaatgtta tgctgttctt tcatgtgaat gtcaagacat ggagggtgtt 3350

 tgtaatttta tggtaaaatt aatccttctt acacataatg gtgtcttaaa 3400

 attgacaaaa aatgagcact tacaattgta tgtctcctca aatgaaaatt 3450

 ctttatctga aattttaaaa gacattgatt ccgcatgtaa ggatttttca 3500

 tctgaagtac aataatgcac aatcagtgtt gctcaaactg ctttatactt 3550

 ataaacagcc atcttaaata agcaacgtat tgtgagtact gatatgtata 3600

 taataaaaat tatcaaagaa aaaaaaaaaa aaaaa 3635

<210> 543
<211> 229
<212> PRT
<213> Homo sapien

<400> 543
 Met Gly Asp Lys Ile Trp Leu Pro Phe Pro Val Leu Leu Leu Ala
   1               5                  10                  15

 Ala Leu Pro Pro Val Leu Leu Pro Gly Ala Ala Gly Phe Thr Pro
                  20                  25                  30

 Ser Leu Asp Ser Asp Phe Thr Phe Thr Leu Pro Ala Gly Gln Lys
                  35                  40                  45

 Glu Cys Phe Tyr Gln Pro Met Pro Leu Lys Ala Ser Leu Glu Ile
                  50                  55                  60

 Glu Tyr Gln Val Leu Asp Gly Ala Gly Leu Asp Ile Asp Phe His
                  65                  70                  75

 Leu Ala Ser Pro Glu Gly Lys Thr Leu Val Phe Glu Gln Arg Lys
                  80                  85                  90

 Ser Asp Gly Val His Thr Val Glu Thr Glu Val Gly Asp Tyr Met
                  95                 100                 105

 Phe Cys Phe Asp Asn Thr Phe Ser Thr Ile Ser Glu Lys Val Ile
                 110                 115                 120

 Phe Phe Glu Leu Ile Leu Asp Asn Met Gly Glu Gln Ala Gln Glu
                 125                 130                 135

 Gln Glu Asp Trp Lys Lys Tyr Ile Thr Gly Thr Asp Ile Leu Asp
                 140                 145                 150

 Met Lys Leu Glu Asp Ile Leu Glu Ser Ile Asn Ser Ile Lys Ser
                 155                 160                 165

 Arg Leu Ser Lys Ser Gly His Ile Gln Ile Leu Leu Arg Ala Phe
                 170                 175                 180

 Glu Ala Arg Asp Arg Asn Ile Gln Glu Ser Asn Phe Asp Arg Val
                 185                 190                 195

 Asn Phe Trp Ser Met Val Asn Leu Val Val Met Val Val Val Ser
                 200                 205                 210

 Ala Ile Gln Val Tyr Met Leu Lys Ser Leu Phe Glu Asp Lys Arg
                 215                 220                 225

 Lys Ser Arg Thr


<210> 544
<211> 3317
<212> DNA
<213> Homo sapien

<400> 544
 ccccagcgag gctccgggag cccttgcctg cgggggtccg gggactcgag 50

 ccggcctccg ccccccggac gcacagccag cgtggtcccc gcgtgcaacg 100

 cgagcgccgg ggagtggctc ctgctttgcc cctcgtgggg gccgagccaa 150

 gaccagtctg caaactccat cccgccggct ggaagaagtc gcggagccgg 200

 caccaaaccc gcagcgtctt cccgcgcgga tcccgggact taaaaagccg 250

 gggccacccc ggcccaggac gggatgcggg tcggtccggt gcgctctgcc 300

 atgagcggcg cctcgcagcc ccgcggcccg gccctgctct tcccagccac 350

 ccgaggcgtc ccggccaaac gcctgctgga cgccgacgac gcggcggctg 400

 tggcggccaa gtgcccgcgc ctctccgagt gctccagccc cccggactac 450

 ctcagccccc ccggctcgcc ctgcagcccg cagcccccgc ctgccgctcc 500

 gggggccggc ggaggctccg ggagcgcgcc ggggcccagc cgcatcgccg 550

 actacctgct gctgccccta gccgagcgcg agcatgtgtc ccgggcgctg 600

 tgcatccaca ctggacgcga gctgcgctgc aaggtgtttc ccattaaaca 650

 ctaccaggac aaaatcaggc cttacatcca gctgccatcg cacagcaaca 700

 ttactggcat tgtggaagtg atccttgggg aaaccaaggc ctatgtcttc 750

 tttgagaagg actttgggga catgcactcc tatgtgcgaa gccggaagag 800

 gctgcgggaa gaggaagccg cccggctctt caagcagatt gtctccgccg 850

 tcgcccactg ccaccagtca gccatcgtgc tgggggacct gaagcttagg 900

 aagttcgtct tctccacgga ggagagaacc cagcttagac tagaaagtct 950

 agaagacaca cacataatga agggggaaga tgatgctttg tcagacaaac 1000

 atggctgccc agcctacgtg agccctgaga tcctcaacac cactgggacc 1050

 tactccggaa aggctgcgga cgtttggagc ctgggggtga tgctctacac 1100

 ccttctggtt ggacgatacc ccttccatga ctcagacccc agtgcccttt 1150

 tctccaaaat tcggcgtgga cagttctgca ttcctgagca catttccccc 1200

 aaagccaggt gcctcattcg cagcctcttg agacgggagc cctccgagag 1250

 actcactgcc cccgagatcc tactgcaccc ctggtttgag tccgtcttgg 1300

 aacccgggta catcgactca gaaataggaa cttcagacca gattgttcca 1350

 gagtaccagg aggacagtga cattagttcc ttcttctgct aatccccaaa 1400

 acctcagaaa cctcataatt cttaacacct ggcatttcca tttctaaaga 1450

 tggacaggcc ctttggcatg gtaccaacca gataatgact gcatcaggat 1500

 gaaagctgct gaactcggca tggcgcctcc tcttctctgt tgggatgagt 1550

 gactttattg atttgagcag catatgctgt gattggctgc cctgcaaatt 1600

 tgtttccctt aaggaaccct caccaactat ctctgctgga tttgggagtt 1650

 ccgcatcttt tgtggagggc agagtatgga catcttacac ccggtggtca 1700

 agtgtgtaat aaacttgagc attcgaatgg gagaaaaagc aaatcgcaca 1750

 atgacatatt ttgagtaata accgtatttt tcacagggtg acaaattggg 1800

 ccaataaatc tgccatcttt gaactcatct ttggtggcta gactgctacg 1850

 gcagcttctc tgatgggaaa gttccttttt tggcttaaca ctcacccttt 1900

 cttcacactc acatttacca atgactctgc tccgtttttg gagcagactg 1950

 ttttaagttg ctcaggagcc tgatggaacc atgaaccgag actcttctct 2000

 gtttcctgcc aagacctcat ctgcactaat gccttctccc tgaccttgac 2050

 acttccccct ttagctataa aagcacttac cagccgaacg tggaacagta 2100

 tcacaaaaga ttccatctcc caacgatttc agaactctga gctcagagag 2150

 actccagatt ttaaaaaata atttgagtgc ttggaaacta ttagcttttt 2200

 aagttccttc caaatatgtt agtacctacc ctttactttt tccccaagac 2250

 catctcaggg tggagcattc tgtctaagag aagaaagata aggaggctcc 2300

 cacccacctc tcccaagagc agacattaaa catctttgtg ctttgaagag 2350

 agtgaatttt ggatagtctt gtgattctca gactaacttc cagaattata 2400

 ctttaacccc tcccagatat ggtccgcctt tggcattgtg tgtacatctg 2450

 cagttttgca tggtgggttg ttaatatttc aaatgtgtgg tttatgaata 2500

 cgtctgtata atcggcttct ggagtgaaac agcaaacccc aaatcttcaa 2550

 agttggaagg aactttaaaa atcatccggt ccaatctctt tcctctttct 2600

 gccacctccc aaggcagaaa tcccctcttc agcttctttt gtaggtggga 2650

 atccagcctc tgttagatat gtccagagat ggaaactcac tcccctacaa 2700

 aagatggagc ttaatggaga aattgcaact ttcattaaaa aacaaattca 2750

 gatgaaatat cagtaactgt cttggacagt gctgaaatca ggtggttaaa 2800

 cgggtaaaca aaatatactg tattttgaga aatggcacaa aaacaggcag 2850

 tcatctttaa gggctatgcc taggcaaact actaacatgc attgtgagaa 2900

 tgccgtgtat acctcacgta ctgtgtactt tgtacatata ttttaccttt 2950

 tatacctatg ttcgattttg ttttgttttg ttctggcttt gaggcttgtt 3000

 ttgttgtctg tgtctgtctg aataacctgc gtgtctaaaa ccacgtgaaa 3050

 tgtgaatgat tattggcaat attaccttga cagaatcatg ggactttgag 3100

 aagagggagg acagaggcct ctgtcgcact aacgctctcg tggttgctcg 3150

 actgttgtat ctgtgataca ttatccgact aaggactctg ggctggcagg 3200

 gccttctgcc gggaaagcta gaaacactag gttcttcctg tacatacgtg 3250

 tatatatgtg aacagtgaga tggccgtttc tgacttgtag agaaatttta 3300

 ataaacctgg tttcgta 3317

<210> 545
<211> 372
<212> PRT
<213> Homo sapien

<400> 545
 Met Arg Val Gly Pro Val Arg Ser Ala Met Ser Gly Ala Ser Gln
   1               5                  10                  15

 Pro Arg Gly Pro Ala Leu Leu Phe Pro Ala Thr Arg Gly Val Pro
                  20                  25                  30

 Ala Lys Arg Leu Leu Asp Ala Asp Asp Ala Ala Ala Val Ala Ala
                  35                  40                  45

 Lys Cys Pro Arg Leu Ser Glu Cys Ser Ser Pro Pro Asp Tyr Leu
                  50                  55                  60

 Ser Pro Pro Gly Ser Pro Cys Ser Pro Gln Pro Pro Pro Ala Ala
                  65                  70                  75

 Pro Gly Ala Gly Gly Gly Ser Gly Ser Ala Pro Gly Pro Ser Arg
                  80                  85                  90

 Ile Ala Asp Tyr Leu Leu Leu Pro Leu Ala Glu Arg Glu His Val
                  95                 100                 105

 Ser Arg Ala Leu Cys Ile His Thr Gly Arg Glu Leu Arg Cys Lys
                 110                 115                 120

 Val Phe Pro Ile Lys His Tyr Gln Asp Lys Ile Arg Pro Tyr Ile
                 125                 130                 135

 Gln Leu Pro Ser His Ser Asn Ile Thr Gly Ile Val Glu Val Ile
                 140                 145                 150

 Leu Gly Glu Thr Lys Ala Tyr Val Phe Phe Glu Lys Asp Phe Gly
                 155                 160                 165

 Asp Met His Ser Tyr Val Arg Ser Arg Lys Arg Leu Arg Glu Glu
                 170                 175                 180

 Glu Ala Ala Arg Leu Phe Lys Gln Ile Val Ser Ala Val Ala His
                 185                 190                 195

 Cys His Gln Ser Ala Ile Val Leu Gly Asp Leu Lys Leu Arg Lys
                 200                 205                 210

 Phe Val Phe Ser Thr Glu Glu Arg Thr Gln Leu Arg Leu Glu Ser
                 215                 220                 225

 Leu Glu Asp Thr His Ile Met Lys Gly Glu Asp Asp Ala Leu Ser
                 230                 235                 240

 Asp Lys His Gly Cys Pro Ala Tyr Val Ser Pro Glu Ile Leu Asn
                 245                 250                 255

 Thr Thr Gly Thr Tyr Ser Gly Lys Ala Ala Asp Val Trp Ser Leu
                 260                 265                 270

 Gly Val Met Leu Tyr Thr Leu Leu Val Gly Arg Tyr Pro Phe His
                 275                 280                 285

 Asp Ser Asp Pro Ser Ala Leu Phe Ser Lys Ile Arg Arg Gly Gln
                 290                 295                 300

 Phe Cys Ile Pro Glu His Ile Ser Pro Lys Ala Arg Cys Leu Ile
                 305                 310                 315

 Arg Ser Leu Leu Arg Arg Glu Pro Ser Glu Arg Leu Thr Ala Pro
                 320                 325                 330

 Glu Ile Leu Leu His Pro Trp Phe Glu Ser Val Leu Glu Pro Gly
                 335                 340                 345

 Tyr Ile Asp Ser Glu Ile Gly Thr Ser Asp Gln Ile Val Pro Glu
                 350                 355                 360

 Tyr Gln Glu Asp Ser Asp Ile Ser Ser Phe Phe Cys
                 365                 370

<210> 546
<211> 1474
<212> DNA
<213> Homo sapien

<400> 546
 agccctccca gtttccgcgc gcctctttgg cagctggtca catggtgagg 50

 gtgggggtga gggggcctct ctagcttgcg gcctgtgtct atggtcgggc 100

 cctctgcgtc cagctgctcc ggaccgagct cgggtgtatg gggccgtagg 150

 aaccggctcc ggggccccga taacgggccg cccccacagc accccgggct 200

 ggcgtgaggg tctcccttga tctgagaatg gctacctctc gatatgagcc 250

 agtggctgaa attggtgtcg gtgcctatgg gacagtgtac aaggcccgtg 300

 atccccacag tggccacttt gtggccctca agagtgtgag agtccccaat 350

 ggaggaggag gtggaggagg ccttcccatc agcacagttc gtgaggtggc 400

 tttactgagg cgactggagg cttttgagca tcccaatgtt gtccggctga 450

 tggacgtctg tgccacatcc cgaactgacc gggagatcaa ggtaaccctg 500

 gtgtttgagc atgtagacca ggacctaagg acatatctgg acaaggcacc 550

 cccaccaggc ttgccagccg aaacgatcaa ggatctgatg cgccagtttc 600

 taagaggcct agatttcctt catgccaatt gcatcgttca ccgagatctg 650

 aagccagaga acattctggt gacaagtggt ggaacagtca agctggctga 700

 ctttggcctg gccagaatct acagctacca gatggcactt acacccgtgg 750

 ttgttacact ctggtaccga gctcccgaag ttcttctgca gtccacatat 800

 gcaacacctg tggacatgtg gagtgttggc tgtatctttg cagagatgtt 850

 tcgtcgaaag cctctcttct gtggaaactc tgaagccgac cagttgggca 900

 aaatctttga cctgattggg ctgcctccag aggatgactg gcctcgagat 950

 gtatccctgc cccgtggagc ctttcccccc agagggcccc gcccagtgca 1000

 gtcggtggta cctgagatgg aggagtcggg agcacagctg ctgctggaaa 1050

 tgctgacttt taacccacac aagcgaatct ctgcctttcg agctctgcag 1100

 cactcttatc tacataagga tgaaggtaat ccggagtgag caatggagtg 1150

 gctgccatgg aaggaagaaa agctgccatt tcccttctgg acactgagag 1200

 ggcaatcttt gcctttatct ctgaggctat ggagggtcct cctccatctt 1250

 tctacagaga ttactttgct gccttaatga cattcccctc ccacctctcc 1300

 ttttgaggct tctccttctc cttcccattt ctctacacta aggggtatgt 1350

 tccctcttgt ccctttccct acctttatat ttggggtcct tttttataca 1400

 ggaaaaacaa aacaaagaaa taatggtctt tttttttttt ttaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaaa aaaa 1474

<210> 547
<211> 303
<212> PRT
<213> Homo sapien

<400> 547
 Met Ala Thr Ser Arg Tyr Glu Pro Val Ala Glu Ile Gly Val Gly
   1               5                  10                  15

 Ala Tyr Gly Thr Val Tyr Lys Ala Arg Asp Pro His Ser Gly His
                  20                  25                  30

 Phe Val Ala Leu Lys Ser Val Arg Val Pro Asn Gly Gly Gly Gly
                  35                  40                  45

 Gly Gly Gly Leu Pro Ile Ser Thr Val Arg Glu Val Ala Leu Leu
                  50                  55                  60

 Arg Arg Leu Glu Ala Phe Glu His Pro Asn Val Val Arg Leu Met
                  65                  70                  75

 Asp Val Cys Ala Thr Ser Arg Thr Asp Arg Glu Ile Lys Val Thr
                  80                  85                  90

 Leu Val Phe Glu His Val Asp Gln Asp Leu Arg Thr Tyr Leu Asp
                  95                 100                 105

 Lys Ala Pro Pro Pro Gly Leu Pro Ala Glu Thr Ile Lys Asp Leu
                 110                 115                 120

 Met Arg Gln Phe Leu Arg Gly Leu Asp Phe Leu His Ala Asn Cys
                 125                 130                 135

 Ile Val His Arg Asp Leu Lys Pro Glu Asn Ile Leu Val Thr Ser
                 140                 145                 150

 Gly Gly Thr Val Lys Leu Ala Asp Phe Gly Leu Ala Arg Ile Tyr
                 155                 160                 165

 Ser Tyr Gln Met Ala Leu Thr Pro Val Val Val Thr Leu Trp Tyr
                 170                 175                 180

 Arg Ala Pro Glu Val Leu Leu Gln Ser Thr Tyr Ala Thr Pro Val
                 185                 190                 195

 Asp Met Trp Ser Val Gly Cys Ile Phe Ala Glu Met Phe Arg Arg
                 200                 205                 210

 Lys Pro Leu Phe Cys Gly Asn Ser Glu Ala Asp Gln Leu Gly Lys
                 215                 220                 225

 Ile Phe Asp Leu Ile Gly Leu Pro Pro Glu Asp Asp Trp Pro Arg
                 230                 235                 240

 Asp Val Ser Leu Pro Arg Gly Ala Phe Pro Pro Arg Gly Pro Arg
                 245                 250                 255

 Pro Val Gln Ser Val Val Pro Glu Met Glu Glu Ser Gly Ala Gln
                 260                 265                 270

 Leu Leu Leu Glu Met Leu Thr Phe Asn Pro His Lys Arg Ile Ser
                 275                 280                 285

 Ala Phe Arg Ala Leu Gln His Ser Tyr Leu His Lys Asp Glu Gly
                 290                 295                 300

 Asn Pro Glu


<210> 548
<211> 1238
<212> DNA
<213> Homo sapien

<400> 548
 gaattcgagg atccgggtac catgggagga aaacttcttc ctggcctggg 50

 ctccgtgccg ctctgtttgc caaccgtcca gtcccgccta ccagtgccgg 100

 gcgctcccca cccctccccc ggctcccccg gtgtccgcca tggccaaagc 150

 ctacgaccac ctcttcaagt tgctgctgat cggggactcg ggggtgggca 200

 agacttgtct gatcattcgc tttgcagagg acaacttcaa caacacttac 250

 atctccacca tcggaattga tttcaagatc cgcactgtgg atatagaggg 300

 gaagaagatc aaactacaag tctgggacac ggctggccaa gagcggttca 350

 agacaataac tactgcctac taccgtggag ccatgggcat tatcctagta 400

 tacgacatca cggatgagaa atctttcgag aatattcaga actggatgaa 450

 aagcatcaag gagaatgcct cggctggggt ggagcgcctc ttgctgggga 500

 acaaatgtga catggaggcc aagaggaagg tgcagaagga gcaggccgat 550

 aagttggctc gagagcatgg aatccgattt ttcgaaacta gtgctaaatc 600

 cagtatgaat gtggatgagg cttttagttc cctggcccgg gacatcttgc 650

 tcaagtcagg aggccggaga tcaggaaacg gcaacaagcc tcccagtact 700

 gacctgaaaa cttgtgacaa gaagaacacc aacaagtgct ccctgggctg 750

 aggacccttt cttgcctccc caccccggaa gctgaacctg agggagacaa 800

 cggcagaggg agtgagcagg ggagaaatag cagaggggct tggagggtca 850

 cataggtaga tggtaaagag aatgaggaga aaaaggagaa aagggaaaag 900

 cagaaaggaa aaaaaggaag agagaggaag ggagaaggga gaggaatgaa 950

 ttgaggaagt gaaagaaggc aaggaggtag gaagagaggg aggaggaaag 1000

 gaaggagaga gatgcctcag gcttcagacc ttacctgggt tttcagggca 1050

 aacataaatg taaatacact gatttattct gttactagat caggttttag 1100

 ggtcctgcaa aaggctagct cggcactaca ctagggaatt tgctcctgtt 1150

 ctgtcacttg tcatggtctt tcttggtatt aaaggccacc atttgcacaa 1200

 aaaaaaaaaa aaaccatggt acccggatcc tcgaattc 1238

<210> 549
<211> 203
<212> PRT
<213> Homo sapien

<400> 549
 Met Ala Lys Ala Tyr Asp His Leu Phe Lys Leu Leu Leu Ile Gly
   1               5                  10                  15

 Asp Ser Gly Val Gly Lys Thr Cys Leu Ile Ile Arg Phe Ala Glu
                  20                  25                  30

 Asp Asn Phe Asn Asn Thr Tyr Ile Ser Thr Ile Gly Ile Asp Phe
                  35                  40                  45

 Lys Ile Arg Thr Val Asp Ile Glu Gly Lys Lys Ile Lys Leu Gln
                  50                  55                  60

 Val Trp Asp Thr Ala Gly Gln Glu Arg Phe Lys Thr Ile Thr Thr
                  65                  70                  75

 Ala Tyr Tyr Arg Gly Ala Met Gly Ile Ile Leu Val Tyr Asp Ile
                  80                  85                  90

 Thr Asp Glu Lys Ser Phe Glu Asn Ile Gln Asn Trp Met Lys Ser
                  95                 100                 105

 Ile Lys Glu Asn Ala Ser Ala Gly Val Glu Arg Leu Leu Leu Gly
                 110                 115                 120

 Asn Lys Cys Asp Met Glu Ala Lys Arg Lys Val Gln Lys Glu Gln
                 125                 130                 135

 Ala Asp Lys Leu Ala Arg Glu His Gly Ile Arg Phe Phe Glu Thr
                 140                 145                 150

 Ser Ala Lys Ser Ser Met Asn Val Asp Glu Ala Phe Ser Ser Leu
                 155                 160                 165

 Ala Arg Asp Ile Leu Leu Lys Ser Gly Gly Arg Arg Ser Gly Asn
                 170                 175                 180

 Gly Asn Lys Pro Pro Ser Thr Asp Leu Lys Thr Cys Asp Lys Lys
                 185                 190                 195

 Asn Thr Asn Lys Cys Ser Leu Gly
                 200

<210> 550
<211> 1700
<212> DNA
<213> Homo sapien

<400> 550
 ggcggcggca gcgggttcgg ttgcgcgtgg cgcacggggt gggagcggag 50

 cccaggccgg gagcaggcgc cgccgccagc gaccatgggg aacgtgttgg 100

 ctgccagctc gccgcccgca gggccgccac cgccgcctgc gccggccctc 150

 gtggggctgc cgccacctcc gccctcgccg ccgggcttca cgctgccgcc 200

 gctgggaggc agcctgggcg ccggcaccag tacgagtcga agttcggaac 250

 ggacccccgg ggctgcaacc gccagcgcct caggggccgc cgaggatggg 300

 gcctgcggct gcctgcccaa cccgggcaca ttcgaggagt gccaccggaa 350

 gtgcaaggag ctgtttccca ttcagatgga gggtgtcaag ctcacagtca 400

 acaaagggtt gagtaaccat tttcaggtca accacacagt agccctcagc 450

 acaatcgggg agtccaacta ccacttcggg gtcacatatg tggggacaaa 500

 gcagctgagt cccacagagg cgttccctgt actggtgggt gacatggaca 550

 acagtggcag tctcaacgct caggtcattc accagctggg ccccggtctc 600

 aggtccaaga tggccatcca gacccagcag tcgaagtttg tgaactggca 650

 ggtggacggg gagtatcggg gctctgactt cacagcagcc gtcaccctgg 700

 ggaacccaga cgtcctcgtg ggttcaggaa tcctcgtagc ccactacctc 750

 cagagcatca cgccttgcct ggccctgggt ggagagctgg tctaccaccg 800

 gcggcctgga gaggagggca ctgtcatgtc tctagctggg aaatacacat 850

 tgaacaactg gttggcaacg gtaacgttgg gccaggcggg catgcacgca 900

 acatactacc acaaagccag tgaccagctg caggtgggtg tggagtttga 950

 ggccagcaca aggatgcagg acaccagcgt ctccttcggg taccagctgg 1000

 acctgcccaa ggccaacctc ctcttcaaag gctctgtgga tagcaactgg 1050

 atcgtgggtg ccacgctgga gaagaagctc ccacccctgc ccctgacact 1100

 ggcccttggg gccttcctga atcaccgcaa gaacaagttt cagtgtggct 1150

 ttggcctcac catcggctga gccctcctgg cccccgcctt ccacgccctt 1200

 ccgattccac ctccacctcc acctccccct gccacagagg ggagacctga 1250

 gcccccctcc cttccctccc cccttggggg tcgggggggg acattggaaa 1300

 ggagggaccc cgccacccca gcagctgagg aggggattct ggaactgaat 1350

 ggcgcttcgg gattctgagt agcaggggca gcatgcccag tgggcctggg 1400

 gtcccgggag ggattccgga attgaggggc acgcaggatt ctgagcacca 1450

 ggggcagagg cggccagaca acctcaggga ggagtgtcct ggcgtcccca 1500

 tcctccaaag ggcctgggcc cgccccgagg gggcagcgag aggagcttcc 1550

 ccatccccgg tcagtccacc ctgccccgtc cactttccca tctcctcggt 1600

 ataaatcatg tttataagtt atggaagaac cgggacattt tacagaaaaa 1650

 aaacaaaaaa caacaaaaaa tatacgtggg aaaaaaaaaa aaaaaaaaaa 1700

<210> 551
<211> 361
<212> PRT
<213> Homo sapien

<400> 551
 Met Gly Asn Val Leu Ala Ala Ser Ser Pro Pro Ala Gly Pro Pro
   1               5                  10                  15

 Pro Pro Pro Ala Pro Ala Leu Val Gly Leu Pro Pro Pro Pro Pro
                  20                  25                  30

 Ser Pro Pro Gly Phe Thr Leu Pro Pro Leu Gly Gly Ser Leu Gly
                  35                  40                  45

 Ala Gly Thr Ser Thr Ser Arg Ser Ser Glu Arg Thr Pro Gly Ala
                  50                  55                  60

 Ala Thr Ala Ser Ala Ser Gly Ala Ala Glu Asp Gly Ala Cys Gly
                  65                  70                  75

 Cys Leu Pro Asn Pro Gly Thr Phe Glu Glu Cys His Arg Lys Cys
                  80                  85                  90

 Lys Glu Leu Phe Pro Ile Gln Met Glu Gly Val Lys Leu Thr Val
                  95                 100                 105

 Asn Lys Gly Leu Ser Asn His Phe Gln Val Asn His Thr Val Ala
                 110                 115                 120

 Leu Ser Thr Ile Gly Glu Ser Asn Tyr His Phe Gly Val Thr Tyr
                 125                 130                 135

 Val Gly Thr Lys Gln Leu Ser Pro Thr Glu Ala Phe Pro Val Leu
                 140                 145                 150

 Val Gly Asp Met Asp Asn Ser Gly Ser Leu Asn Ala Gln Val Ile
                 155                 160                 165

 His Gln Leu Gly Pro Gly Leu Arg Ser Lys Met Ala Ile Gln Thr
                 170                 175                 180

 Gln Gln Ser Lys Phe Val Asn Trp Gln Val Asp Gly Glu Tyr Arg
                 185                 190                 195

 Gly Ser Asp Phe Thr Ala Ala Val Thr Leu Gly Asn Pro Asp Val
                 200                 205                 210

 Leu Val Gly Ser Gly Ile Leu Val Ala His Tyr Leu Gln Ser Ile
                 215                 220                 225

 Thr Pro Cys Leu Ala Leu Gly Gly Glu Leu Val Tyr His Arg Arg
                 230                 235                 240

 Pro Gly Glu Glu Gly Thr Val Met Ser Leu Ala Gly Lys Tyr Thr
                 245                 250                 255

 Leu Asn Asn Trp Leu Ala Thr Val Thr Leu Gly Gln Ala Gly Met
                 260                 265                 270

 His Ala Thr Tyr Tyr His Lys Ala Ser Asp Gln Leu Gln Val Gly
                 275                 280                 285

 Val Glu Phe Glu Ala Ser Thr Arg Met Gln Asp Thr Ser Val Ser
                 290                 295                 300

 Phe Gly Tyr Gln Leu Asp Leu Pro Lys Ala Asn Leu Leu Phe Lys
                 305                 310                 315

 Gly Ser Val Asp Ser Asn Trp Ile Val Gly Ala Thr Leu Glu Lys
                 320                 325                 330

 Lys Leu Pro Pro Leu Pro Leu Thr Leu Ala Leu Gly Ala Phe Leu
                 335                 340                 345

 Asn His Arg Lys Asn Lys Phe Gln Cys Gly Phe Gly Leu Thr Ile
                 350                 355                 360

 Gly


<210> 552
<211> 2881
<212> DNA
<213> Homo sapien

<400> 552
 acagaagtgc tagaagccag tgctcgtgaa ctaaggagaa aaagaacaga 50

 caagggaaca gcctggacat ggcatcagag atccacatga caggcccaat 100

 gtgcctcatt gagaacacta atgggcgact gatggcgaat ccagaagctc 150

 tgaagatcct ttctgccatt acacagccta tggtggtggt ggcaattgtg 200

 ggcctctacc gcacaggcaa atcctacctg atgaacaagc tggctggaaa 250

 gaaaaagggc ttctctctgg gctccacggt gcagtctcac actaaaggaa 300

 tctggatgtg gtgtgtgccc caccccaaga agccaggcca catcctagtt 350

 ctgctggaca ccgagggtct gggagatgta gagaagggtg acaaccagaa 400

 tgactcctgg atcttcgccc tggccgtcct cctgagcagc accttcgtgt 450

 acaatagcat aggaaccatc aaccagcagg ctatggacca actgtactat 500

 gtgacagagc tgacacatag aatccgatca aaatcctcac ctgatgagaa 550

 tgagaatgag gttgaggatt cagctgactt tgtgagcttc ttcccagact 600

 ttgtgtggac actgagagat ttctccctgg acttggaagc agatggacaa 650

 cccctcacac cagatgagta cctgacatac tccctgaagc tgaagaaagg 700

 taccagtcaa aaagatgaaa cttttaacct gcccagactc tgtatccgga 750

 aattcttccc aaagaaaaaa tgctttgtct ttgatcggcc cgttcaccgc 800

 aggaagcttg cccagctcga gaaactacaa gatgaagagc tggaccccga 850

 atttgtgcaa caagtagcag acttctgttc ctacatcttt agtaattcca 900

 aaactaaaac tctttcagga ggcatccagg tcaacgggcc tcgtctagag 950

 agcctggtgc tgacctacgt caatgccatc agcagtgggg atctgccgtg 1000

 catggagaac gcagtcctgg ccttggccca gatagagaac tcagctgcag 1050

 tgcaaaaggc tattgcccac tatgaacagc agatgggcca gaaggtgcag 1100

 ctgcccacag aaagcctcca ggagctgctg gacctgcaca gggacagtga 1150

 gagagaggcc attgaagtct tcatcaggag ttccttcaaa gatgtggacc 1200

 atctatttca aaaggagtta gcggcccagc tagaaaaaaa gcgggatgac 1250

 ttttgtaaac agaatcagga agcatcatca gatcgttgct caggtttact 1300

 tcaggtcatt ttcagtcctc tagaagaaga agtgaaggcg ggaatttatt 1350

 cgaaaccagg gggctatcgt ctctttgttc agaagctaca agacctgaag 1400

 aaaaagtact atgaggaacc gaggaagggg atacaggctg aagagattct 1450

 gcagacatac ttgaaatcca aggagtctat gactgatgca attctccaga 1500

 cagaccagac tctcacagaa aaagaaaagg agattgaagt ggaacgtgtg 1550

 aaagctgagt ctgcacaggc ttcagcaaaa atgttgcagg aaatgcaaag 1600

 aaagaatgag cagatgatgg aacagaagga gaggagttat caggaacact 1650

 tgaaacaact gactgagaag atggagaacg acagggtcca gttgctgaaa 1700

 gagcaagaga ggaccctcgc tcttaaactt caggaacagg agcaactact 1750

 aaaagaggga tttcaaaaag aaagcagaat aatgaaaaat gagatacagg 1800

 atctccagac gaaaatgaga cgacgaaagg catgtaccat aagctaaaga 1850

 ccagagcctt cctgtcaccc ctaaccaagg cataattgaa acaattttag 1900

 aatttggaac aagcgtcact acatttgata ataattagat cttgcatcat 1950

 aacaccaaaa gtttataaag gcatgtggta caatgatcaa aatcatgttt 2000

 tttcttaaaa aaaaaaaaaa gactgtaaat tgtgcaacaa agatgcattt 2050

 acctctgtat caactcagga aatctcataa gctggtacca ctcaggagaa 2100

 gtttattctt ccagatgacc agcagtagac aaatggatac tgagcagagt 2150

 cttaggtaaa agtcttggga aatatttggg cattggtctg gccaagtcta 2200

 caatgtccca atatcaagga caaccaccct agcttcttag tgaagacaat 2250

 gtacagttat ccattagatc aagactacac ggtctatgag caataatgtg 2300

 atttctggac attgcccatg tataatcctc actgatgatt tcaagctaaa 2350

 gcaaaccacc ttatacagag atctagaatc tctttatgtt ctccagagga 2400

 aggtggaaga aaccatgggc aggagtagga attgagtgat aaacaattgg 2450

 gctaatgaag aaaacttctc ttattgttca gttcatccag attataactt 2500

 caatgggaca ctttagacca ttagacaatt gacactggat taaacaaatt 2550

 cacataatgc caaatacaca atgtatttat agcaacgtat aatttgcaaa 2600

 gatggacttt aaaagatgct gtgtaactaa actgaaataa ttcaattact 2650

 tattatttag aatgttaaag cttatgatag tcttttctaa ttcttaacac 2700

 tcatacttga aatctttccg agtttcccca gaagagaata tgggattttt 2750

 tttgacattt ttgacccatt taataatgct cttgtgttta cctagtatat 2800

 gtagactttg tcttatgtgt caaaagtcct aggaaagtgg ttgatgtttc 2850

 ttatagcaat taaaaattat ttttgaactg a 2881

<210> 553
<211> 592
<212> PRT
<213> Homo sapien

<400> 553
 Met Ala Ser Glu Ile His Met Thr Gly Pro Met Cys Leu Ile Glu
   1               5                  10                  15

 Asn Thr Asn Gly Arg Leu Met Ala Asn Pro Glu Ala Leu Lys Ile
                  20                  25                  30

 Leu Ser Ala Ile Thr Gln Pro Met Val Val Val Ala Ile Val Gly
                  35                  40                  45

 Leu Tyr Arg Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly
                  50                  55                  60

 Lys Lys Lys Gly Phe Ser Leu Gly Ser Thr Val Gln Ser His Thr
                  65                  70                  75

 Lys Gly Ile Trp Met Trp Cys Val Pro His Pro Lys Lys Pro Gly
                  80                  85                  90

 His Ile Leu Val Leu Leu Asp Thr Glu Gly Leu Gly Asp Val Glu
                  95                 100                 105

 Lys Gly Asp Asn Gln Asn Asp Ser Trp Ile Phe Ala Leu Ala Val
                 110                 115                 120

 Leu Leu Ser Ser Thr Phe Val Tyr Asn Ser Ile Gly Thr Ile Asn
                 125                 130                 135

 Gln Gln Ala Met Asp Gln Leu Tyr Tyr Val Thr Glu Leu Thr His
                 140                 145                 150

 Arg Ile Arg Ser Lys Ser Ser Pro Asp Glu Asn Glu Asn Glu Val
                 155                 160                 165

 Glu Asp Ser Ala Asp Phe Val Ser Phe Phe Pro Asp Phe Val Trp
                 170                 175                 180

 Thr Leu Arg Asp Phe Ser Leu Asp Leu Glu Ala Asp Gly Gln Pro
                 185                 190                 195

 Leu Thr Pro Asp Glu Tyr Leu Thr Tyr Ser Leu Lys Leu Lys Lys
                 200                 205                 210

 Gly Thr Ser Gln Lys Asp Glu Thr Phe Asn Leu Pro Arg Leu Cys
                 215                 220                 225

 Ile Arg Lys Phe Phe Pro Lys Lys Lys Cys Phe Val Phe Asp Arg
                 230                 235                 240

 Pro Val His Arg Arg Lys Leu Ala Gln Leu Glu Lys Leu Gln Asp
                 245                 250                 255

 Glu Glu Leu Asp Pro Glu Phe Val Gln Gln Val Ala Asp Phe Cys
                 260                 265                 270

 Ser Tyr Ile Phe Ser Asn Ser Lys Thr Lys Thr Leu Ser Gly Gly
                 275                 280                 285

 Ile Gln Val Asn Gly Pro Arg Leu Glu Ser Leu Val Leu Thr Tyr
                 290                 295                 300

 Val Asn Ala Ile Ser Ser Gly Asp Leu Pro Cys Met Glu Asn Ala
                 305                 310                 315

 Val Leu Ala Leu Ala Gln Ile Glu Asn Ser Ala Ala Val Gln Lys
                 320                 325                 330

 Ala Ile Ala His Tyr Glu Gln Gln Met Gly Gln Lys Val Gln Leu
                 335                 340                 345

 Pro Thr Glu Ser Leu Gln Glu Leu Leu Asp Leu His Arg Asp Ser
                 350                 355                 360

 Glu Arg Glu Ala Ile Glu Val Phe Ile Arg Ser Ser Phe Lys Asp
                 365                 370                 375

 Val Asp His Leu Phe Gln Lys Glu Leu Ala Ala Gln Leu Glu Lys
                 380                 385                 390

 Lys Arg Asp Asp Phe Cys Lys Gln Asn Gln Glu Ala Ser Ser Asp
                 395                 400                 405

 Arg Cys Ser Gly Leu Leu Gln Val Ile Phe Ser Pro Leu Glu Glu
                 410                 415                 420

 Glu Val Lys Ala Gly Ile Tyr Ser Lys Pro Gly Gly Tyr Arg Leu
                 425                 430                 435

 Phe Val Gln Lys Leu Gln Asp Leu Lys Lys Lys Tyr Tyr Glu Glu
                 440                 445                 450

 Pro Arg Lys Gly Ile Gln Ala Glu Glu Ile Leu Gln Thr Tyr Leu
                 455                 460                 465

 Lys Ser Lys Glu Ser Met Thr Asp Ala Ile Leu Gln Thr Asp Gln
                 470                 475                 480

 Thr Leu Thr Glu Lys Glu Lys Glu Ile Glu Val Glu Arg Val Lys
                 485                 490                 495

 Ala Glu Ser Ala Gln Ala Ser Ala Lys Met Leu Gln Glu Met Gln
                 500                 505                 510

 Arg Lys Asn Glu Gln Met Met Glu Gln Lys Glu Arg Ser Tyr Gln
                 515                 520                 525

 Glu His Leu Lys Gln Leu Thr Glu Lys Met Glu Asn Asp Arg Val
                 530                 535                 540

 Gln Leu Leu Lys Glu Gln Glu Arg Thr Leu Ala Leu Lys Leu Gln
                 545                 550                 555

 Glu Gln Glu Gln Leu Leu Lys Glu Gly Phe Gln Lys Glu Ser Arg
                 560                 565                 570

 Ile Met Lys Asn Glu Ile Gln Asp Leu Gln Thr Lys Met Arg Arg
                 575                 580                 585

 Arg Lys Ala Cys Thr Ile Ser
                 590

<210> 554
<211> 2881
<212> DNA
<213> Homo sapien

<400> 554
 acagaagtgc tagaagccag tgctcgtgaa ctaaggagaa aaagaacaga 50

 caagggaaca gcctggacat ggcatcagag atccacatga caggcccaat 100

 gtgcctcatt gagaacacta atgggcgact gatggcgaat ccagaagctc 150

 tgaagatcct ttctgccatt acacagccta tggtggtggt ggcaattgtg 200

 ggcctctacc gcacaggcaa atcctacctg atgaacaagc tggctggaaa 250

 gaaaaagggc ttctctctgg gctccacggt gcagtctcac actaaaggaa 300

 tctggatgtg gtgtgtgccc caccccaaga agccaggcca catcctagtt 350

 ctgctggaca ccgagggtct gggagatgta gagaagggtg acaaccagaa 400

 tgactcctgg atcttcgccc tggccgtcct cctgagcagc accttcgtgt 450

 acaatagcat aggaaccatc aaccagcagg ctatggacca actgtactat 500

 gtgacagagc tgacacatag aatccgatca aaatcctcac ctgatgagaa 550

 tgagaatgag gttgaggatt cagctgactt tgtgagcttc ttcccagact 600

 ttgtgtggac actgagagat ttctccctgg acttggaagc agatggacaa 650

 cccctcacac cagatgagta cctgacatac tccctgaagc tgaagaaagg 700

 taccagtcaa aaagatgaaa cttttaacct gcccagactc tgtatccgga 750

 aattcttccc aaagaaaaaa tgctttgtct ttgatcggcc cgttcaccgc 800

 aggaagcttg cccagctcga gaaactacaa gatgaagagc tggaccccga 850

 atttgtgcaa caagtagcag acttctgttc ctacatcttt agtaattcca 900

 aaactaaaac tctttcagga ggcatccagg tcaacgggcc tcgtctagag 950

 agcctggtgc tgacctacgt caatgccatc agcagtgggg atctgccgtg 1000

 catggagaac gcagtcctgg ccttggccca gatagagaac tcagctgcag 1050

 tgcaaaaggc tattgcccac tatgaacagc agatgggcca gaaggtgcag 1100

 ctgcccacag aaagcctcca ggagctgctg gacctgcaca gggacagtga 1150

 gagagaggcc attgaagtct tcatcaggag ttccttcaaa gatgtggacc 1200

 atctatttca aaaggagtta gcggcccagc tagaaaaaaa gcgggatgac 1250

 ttttgtaaac agaatcagga agcatcatca gatcgttgct caggtttact 1300

 tcaggtcatt ttcagtcctc tagaagaaga agtgaaggcg ggaatttatt 1350

 cgaaaccagg gggctatcgt ctctttgttc agaagctaca agacctgaag 1400

 aaaaagtact atgaggaacc gaggaagggg atacaggctg aagagattct 1450

 gcagacatac ttgaaatcca aggagtctat gactgatgca attctccaga 1500

 cagaccagac tctcacagaa aaagaaaagg agattgaagt ggaacgtgtg 1550

 aaagctgagt ctgcacaggc ttcagcaaaa atgttgcagg aaatgcaaag 1600

 aaagaatgag cagatgatgg aacagaagga gaggagttat caggaacact 1650

 tgaaacaact gactgagaag atggagaacg acagggtcca gttgctgaaa 1700

 gagcaagaga ggaccctcgc tcttaaactt caggaacagg agcaactact 1750

 aaaagaggga tttcaaaaag aaagcagaat aatgaaaaat gagatacagg 1800

 atctccagac gaaaatgaga cgacgaaagg catgtaccat aagctaaaga 1850

 ccagagcctt cctgtcaccc ctaaccaagg cataattgaa acaattttag 1900

 aatttggaac aagcgtcact acatttgata ataattagat cttgcatcat 1950

 aacaccaaaa gtttataaag gcatgtggta caatgatcaa aatcatgttt 2000

 tttcttaaaa aaaaaaaaaa gactgtaaat tgtgcaacaa agatgcattt 2050

 acctctgtat caactcagga aatctcataa gctggtacca ctcaggagaa 2100

 gtttattctt ccagatgacc agcagtagac aaatggatac tgagcagagt 2150

 cttaggtaaa agtcttggga aatatttggg cattggtctg gccaagtcta 2200

 caatgtccca atatcaagga caaccaccct agcttcttag tgaagacaat 2250

 gtacagttat ccattagatc aagactacac ggtctatgag caataatgtg 2300

 atttctggac attgcccatg tataatcctc actgatgatt tcaagctaaa 2350

 gcaaaccacc ttatacagag atctagaatc tctttatgtt ctccagagga 2400

 aggtggaaga aaccatgggc aggagtagga attgagtgat aaacaattgg 2450

 gctaatgaag aaaacttctc ttattgttca gttcatccag attataactt 2500

 caatgggaca ctttagacca ttagacaatt gacactggat taaacaaatt 2550

 cacataatgc caaatacaca atgtatttat agcaacgtat aatttgcaaa 2600

 gatggacttt aaaagatgct gtgtaactaa actgaaataa ttcaattact 2650

 tattatttag aatgttaaag cttatgatag tcttttctaa ttcttaacac 2700

 tcatacttga aatctttccg agtttcccca gaagagaata tgggattttt 2750

 tttgacattt ttgacccatt taataatgct cttgtgttta cctagtatat 2800

 gtagactttg tcttatgtgt caaaagtcct aggaaagtgg ttgatgtttc 2850

 ttatagcaat taaaaattat ttttgaactg a 2881

<210> 555
<211> 592
<212> PRT
<213> Homo sapien

<400> 555
 Met Ala Ser Glu Ile His Met Thr Gly Pro Met Cys Leu Ile Glu
   1               5                  10                  15

 Asn Thr Asn Gly Arg Leu Met Ala Asn Pro Glu Ala Leu Lys Ile
                  20                  25                  30

 Leu Ser Ala Ile Thr Gln Pro Met Val Val Val Ala Ile Val Gly
                  35                  40                  45

 Leu Tyr Arg Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly
                  50                  55                  60

 Lys Lys Lys Gly Phe Ser Leu Gly Ser Thr Val Gln Ser His Thr
                  65                  70                  75

 Lys Gly Ile Trp Met Trp Cys Val Pro His Pro Lys Lys Pro Gly
                  80                  85                  90

 His Ile Leu Val Leu Leu Asp Thr Glu Gly Leu Gly Asp Val Glu
                  95                 100                 105

 Lys Gly Asp Asn Gln Asn Asp Ser Trp Ile Phe Ala Leu Ala Val
                 110                 115                 120

 Leu Leu Ser Ser Thr Phe Val Tyr Asn Ser Ile Gly Thr Ile Asn
                 125                 130                 135

 Gln Gln Ala Met Asp Gln Leu Tyr Tyr Val Thr Glu Leu Thr His
                 140                 145                 150

 Arg Ile Arg Ser Lys Ser Ser Pro Asp Glu Asn Glu Asn Glu Val
                 155                 160                 165

 Glu Asp Ser Ala Asp Phe Val Ser Phe Phe Pro Asp Phe Val Trp
                 170                 175                 180

 Thr Leu Arg Asp Phe Ser Leu Asp Leu Glu Ala Asp Gly Gln Pro
                 185                 190                 195

 Leu Thr Pro Asp Glu Tyr Leu Thr Tyr Ser Leu Lys Leu Lys Lys
                 200                 205                 210

 Gly Thr Ser Gln Lys Asp Glu Thr Phe Asn Leu Pro Arg Leu Cys
                 215                 220                 225

 Ile Arg Lys Phe Phe Pro Lys Lys Lys Cys Phe Val Phe Asp Arg
                 230                 235                 240

 Pro Val His Arg Arg Lys Leu Ala Gln Leu Glu Lys Leu Gln Asp
                 245                 250                 255

 Glu Glu Leu Asp Pro Glu Phe Val Gln Gln Val Ala Asp Phe Cys
                 260                 265                 270

 Ser Tyr Ile Phe Ser Asn Ser Lys Thr Lys Thr Leu Ser Gly Gly
                 275                 280                 285

 Ile Gln Val Asn Gly Pro Arg Leu Glu Ser Leu Val Leu Thr Tyr
                 290                 295                 300

 Val Asn Ala Ile Ser Ser Gly Asp Leu Pro Cys Met Glu Asn Ala
                 305                 310                 315

 Val Leu Ala Leu Ala Gln Ile Glu Asn Ser Ala Ala Val Gln Lys
                 320                 325                 330

 Ala Ile Ala His Tyr Glu Gln Gln Met Gly Gln Lys Val Gln Leu
                 335                 340                 345

 Pro Thr Glu Ser Leu Gln Glu Leu Leu Asp Leu His Arg Asp Ser
                 350                 355                 360

 Glu Arg Glu Ala Ile Glu Val Phe Ile Arg Ser Ser Phe Lys Asp
                 365                 370                 375

 Val Asp His Leu Phe Gln Lys Glu Leu Ala Ala Gln Leu Glu Lys
                 380                 385                 390

 Lys Arg Asp Asp Phe Cys Lys Gln Asn Gln Glu Ala Ser Ser Asp
                 395                 400                 405

 Arg Cys Ser Gly Leu Leu Gln Val Ile Phe Ser Pro Leu Glu Glu
                 410                 415                 420

 Glu Val Lys Ala Gly Ile Tyr Ser Lys Pro Gly Gly Tyr Arg Leu
                 425                 430                 435

 Phe Val Gln Lys Leu Gln Asp Leu Lys Lys Lys Tyr Tyr Glu Glu
                 440                 445                 450

 Pro Arg Lys Gly Ile Gln Ala Glu Glu Ile Leu Gln Thr Tyr Leu
                 455                 460                 465

 Lys Ser Lys Glu Ser Met Thr Asp Ala Ile Leu Gln Thr Asp Gln
                 470                 475                 480

 Thr Leu Thr Glu Lys Glu Lys Glu Ile Glu Val Glu Arg Val Lys
                 485                 490                 495

 Ala Glu Ser Ala Gln Ala Ser Ala Lys Met Leu Gln Glu Met Gln
                 500                 505                 510

 Arg Lys Asn Glu Gln Met Met Glu Gln Lys Glu Arg Ser Tyr Gln
                 515                 520                 525

 Glu His Leu Lys Gln Leu Thr Glu Lys Met Glu Asn Asp Arg Val
                 530                 535                 540

 Gln Leu Leu Lys Glu Gln Glu Arg Thr Leu Ala Leu Lys Leu Gln
                 545                 550                 555

 Glu Gln Glu Gln Leu Leu Lys Glu Gly Phe Gln Lys Glu Ser Arg
                 560                 565                 570

 Ile Met Lys Asn Glu Ile Gln Asp Leu Gln Thr Lys Met Arg Arg
                 575                 580                 585

 Arg Lys Ala Cys Thr Ile Ser
                 590

<210> 556
<211> 2281
<212> DNA
<213> Homo sapien

<400> 556
 agctgaggtg tgagcagctg ccgaagtcag ttccttgtgg agccggagct 50

 gggcgcggat tcgccgaggc accgaggcac tcagaggagg tgagagagcg 100

 gcggcagaca acaggggacc ccgggccggc ggcccagagc cgagccaagc 150

 gtgcccgcgt gtgtccctgc gtgtccgcga ggatgcgtgt tcgcgggtgt 200

 gtgctgcgtt cacaggtgtt tctgcggcag gcgccatgtc agaaccggct 250

 ggggatgtcc gtcagaaccc atgcggcagc aaggcctgcc gccgcctctt 300

 cggcccagtg gacagcgagc agctgagccg cgactgtgat gcgctaatgg 350

 cgggctgcat ccaggaggcc cgtgagcgat ggaacttcga ctttgtcacc 400

 gagacaccac tggagggtga cttcgcctgg gagcgtgtgc ggggccttgg 450

 cctgcccaag ctctaccttc ccacggggcc ccggcgaggc cgggatgagt 500

 tgggaggagg caggcggcct ggcacctcac ctgctctgct gcaggggaca 550

 gcagaggaag accatgtgga cctgtcactg tcttgtaccc ttgtgcctcg 600

 ctcaggggag caggctgaag ggtccccagg tggacctgga gactctcagg 650

 gtcgaaaacg gcggcagacc agcatgacag atttctacca ctccaaacgc 700

 cggctgatct tctccaagag gaagccctaa tccgcccaca ggaagcctgc 750

 agtcctggaa gcgcgagggc ctcaaaggcc cgctctacat cttctgcctt 800

 agtctcagtt tgtgtgtctt aattattatt tgtgttttaa tttaaacacc 850

 tcctcatgta cataccctgg ccgccccctg ccccccagcc tctggcatta 900

 gaattattta aacaaaaact aggcggttga atgagaggtt cctaagagtg 950

 ctgggcattt ttattttatg aaatactatt taaagcctcc tcatcccgtg 1000

 ttctcctttt cctctctccc ggaggttggg tgggccggct tcatgccagc 1050

 tacttcctcc tccccacttg tccgctgggt ggtaccctct ggaggggtgt 1100

 ggctccttcc catcgctgtc acaggcggtt atgaaattca ccccctttcc 1150

 tggacactca gacctgaatt ctttttcatt tgagaagtaa acagatggca 1200

 ctttgaaggg gcctcaccga gtgggggcat catcaaaaac tttggagtcc 1250

 cctcacctcc tctaaggttg ggcagggtga ccctgaagtg agcacagcct 1300

 agggctgagc tggggacctg gtaccctcct ggctcttgat acccccctct 1350

 gtcttgtgaa ggcaggggga aggtggggtc ctggagcaga ccaccccgcc 1400

 tgccctcatg gcccctctga cctgcactgg ggagcccgtc tcagtgttga 1450

 gccttttccc tctttggctc ccctgtacct tttgaggagc cccagctacc 1500

 cttcttctcc agctgggctc tgcaattccc ctctgctgct gtccctcccc 1550

 cttgtccttt cccttcagta ccctctcagc tccaggtggc tctgaggtgc 1600

 ctgtcccacc cccaccccca gctcaatgga ctggaagggg aagggacaca 1650

 caagaagaag ggcaccctag ttctacctca ggcagctcaa gcagcgaccg 1700

 ccccctcctc tagctgtggg ggtgagggtc ccatgtggtg gcacaggccc 1750

 ccttgagtgg ggttatctct gtgttagggg tatatgatgg gggagtagat 1800

 ctttctagga gggagacact ggcccctcaa atcgtccagc gaccttcctc 1850

 atccacccca tccctcccca gttcattgca ctttgattag cagcggaaca 1900

 aggagtcaga cattttaaga tggtggcagt agaggctatg gacagggcat 1950

 gccacgtggg ctcatatggg gctgggagta gttgtctttc ctggcactaa 2000

 cgttgagccc ctggaggcac tgaagtgctt agtgtacttg gagtattggg 2050

 gtctgacccc aaacaccttc cagctcctgt aacatactgg cctggactgt 2100

 tttctctcgg ctccccatgt gtcctggttc ccgtttctcc acctagactg 2150

 taaacctctc gagggcaggg accacaccct gtactgttct gtgtctttca 2200

 cagctcctcc cacaatgctg aatatacagc aggtgctcaa taaatgattc 2250

 ttagtgactt taaaaaaaaa aaaaaaaaaa a 2281

<210> 557
<211> 164
<212> PRT
<213> Homo sapien

<400> 557
 Met Ser Glu Pro Ala Gly Asp Val Arg Gln Asn Pro Cys Gly Ser
   1               5                  10                  15

 Lys Ala Cys Arg Arg Leu Phe Gly Pro Val Asp Ser Glu Gln Leu
                  20                  25                  30

 Ser Arg Asp Cys Asp Ala Leu Met Ala Gly Cys Ile Gln Glu Ala
                  35                  40                  45

 Arg Glu Arg Trp Asn Phe Asp Phe Val Thr Glu Thr Pro Leu Glu
                  50                  55                  60

 Gly Asp Phe Ala Trp Glu Arg Val Arg Gly Leu Gly Leu Pro Lys
                  65                  70                  75

 Leu Tyr Leu Pro Thr Gly Pro Arg Arg Gly Arg Asp Glu Leu Gly
                  80                  85                  90

 Gly Gly Arg Arg Pro Gly Thr Ser Pro Ala Leu Leu Gln Gly Thr
                  95                 100                 105

 Ala Glu Glu Asp His Val Asp Leu Ser Leu Ser Cys Thr Leu Val
                 110                 115                 120

 Pro Arg Ser Gly Glu Gln Ala Glu Gly Ser Pro Gly Gly Pro Gly
                 125                 130                 135

 Asp Ser Gln Gly Arg Lys Arg Arg Gln Thr Ser Met Thr Asp Phe
                 140                 145                 150

 Tyr His Ser Lys Arg Arg Leu Ile Phe Ser Lys Arg Lys Pro
                 155                 160

<210> 558
<211> 837
<212> DNA
<213> Homo sapien

<400> 558
 gaattccgcg gcggcgcctc aatgcctaaa ggaggaagaa agggaggcca 50

 caaaggccgg gcgaggcagt atacaagccc tgaggagatc gacgcgcagc 100

 tgcaggctga gaagcagaag gccagggaag aagaggagca aaaagaaggt 150

 ggagatgggg ctgcaggtga ccccaaaaag gagaagaaat ctctagactc 200

 agatgagagt gaggatgaag aagatgacta ccagcaaaag cgcaaaggcg 250

 ttgaagggct catcgacatc gagaacccca accgggtggc acagacaacc 300

 aaaaaggtca cacaactgga tctggacggg ccaaaggagc tttcgaggag 350

 agaacgagaa gagattgaga agcagaaggc aaaagagcgt tacatgaaaa 400

 tgcacttggc cgggaagaca gagcaagcca aggctgacct ggcccggctg 450

 gccatcatcc ggaaacagcg ggaggaggct gcccggaaga aggaagagga 500

 aaggaaagca aaagacgatg ccacattgtc aggaaaacga atgcagtcac 550

 tctccctgaa taagtaactg cgacccgtgg gaggagatgc cggggacctg 600

 ggccgcgctg ccaggacctc tgctgtgtct cgcccaccct gtgccctggc 650

 gccgctgcaa cagcccctca tggccaggag ccccccatgc ctgggcctcc 700

 tcttcatctt ggcacagaaa ttgtttgggg gatggggggg ggactggggg 750

 aggggtagct gctatctttg agacagaaag atgcaggaca gcatttcata 800

 tgtaaccatt tgaatgtttt tgctgttttt agaattc 837

<210> 559
<211> 181
<212> PRT
<213> Homo sapien

<400> 559
 Met Pro Lys Gly Gly Arg Lys Gly Gly His Lys Gly Arg Ala Arg
   1               5                  10                  15

 Gln Tyr Thr Ser Pro Glu Glu Ile Asp Ala Gln Leu Gln Ala Glu
                  20                  25                  30

 Lys Gln Lys Ala Arg Glu Glu Glu Glu Gln Lys Glu Gly Gly Asp
                  35                  40                  45

 Gly Ala Ala Gly Asp Pro Lys Lys Glu Lys Lys Ser Leu Asp Ser
                  50                  55                  60

 Asp Glu Ser Glu Asp Glu Glu Asp Asp Tyr Gln Gln Lys Arg Lys
                  65                  70                  75

 Gly Val Glu Gly Leu Ile Asp Ile Glu Asn Pro Asn Arg Val Ala
                  80                  85                  90

 Gln Thr Thr Lys Lys Val Thr Gln Leu Asp Leu Asp Gly Pro Lys
                  95                 100                 105

 Glu Leu Ser Arg Arg Glu Arg Glu Glu Ile Glu Lys Gln Lys Ala
                 110                 115                 120

 Lys Glu Arg Tyr Met Lys Met His Leu Ala Gly Lys Thr Glu Gln
                 125                 130                 135

 Ala Lys Ala Asp Leu Ala Arg Leu Ala Ile Ile Arg Lys Gln Arg
                 140                 145                 150

 Glu Glu Ala Ala Arg Lys Lys Glu Glu Glu Arg Lys Ala Lys Asp
                 155                 160                 165

 Asp Ala Thr Leu Ser Gly Lys Arg Met Gln Ser Leu Ser Leu Asn
                 170                 175                 180

 Lys


<210> 560
<211> 1504
<212> DNA
<213> Homo sapien

<400> 560
 ccacgctcgt gccgcccccc ccgcgctccc agttgacgct ctgggccgcc 50

 acctccgcgg accctgagcg caagagccaa gccgccagcg ctgcgatgtg 100

 ggccacgctg ccgctgctct gcgccggggc ctggctcctg ggagtccccg 150

 tctgcggtgc cgccgaactg tgcgtgaact ccttagagaa gtttcacttc 200

 aagtcatgga tgtctaagca ccgtaagacc tacagtacgg aggagtacca 250

 ccacaggctg cagacgtttg ccagcaactg gaggaagata aacgcccaca 300

 acaatgggaa ccacacattt aaaatggcac tgaaccaatt ttcagacatg 350

 agctttgctg aaataaaaca caagtatctc tggtcagagc ctcagaattg 400

 ctcagccacc aaaagtaact accttcgagg tactggtccc tacccacctt 450

 ccgtggactg gcggaaaaaa ggaaattttg tctcacctgt gaaaaatcag 500

 ggtgcctgcg gcagttgctg gactttctcc accactgggg ccctggagtc 550

 tgcgatcgcc atcgcaaccg gaaagatgct gtccttggcg gaacagcagc 600

 tggtggactg cgcccaggac ttcaataatc acggctgcca agggggtctc 650

 cccagccagg ctttcgagta tatcctgtac aacaagggga tcatgggtga 700

 agacacctac ccctaccagg gcaaggatgg ttattgcaag ttccaacctg 750

 gaaaggccat cggctttgtc aaggatgtag ccaacatcac aatctatgac 800

 gaggaagcga tggtggaggc tgtggccctc tacaaccctg tgagctttgc 850

 ctttgaggtg actcaggact tcatgatgta tagaacgggc atctactcca 900

 gtacttcctg ccataaaact ccagataaag taaaccatgc agtactggct 950

 gttgggtatg gagaaaaaaa tgggatccct tactggatcg tgaaaaactc 1000

 ttggggtccc cagtggggaa tgaacgggta cttcctcatc gagcgcggaa 1050

 agaacatgtg tggcctggct gcctgcgcct cctaccccat ccctctggtg 1100

 tgagccgtgg cagccgcagc gcagactggc ggagaaggag aggaacgggc 1150

 agcctgggcc tgggtggaaa tcctgccctg gaggaagttg tggggagatc 1200

 cactgggacc cccaacattc tgccctcacc tctgtgccca gcctggaaac 1250

 ctacagacaa ggaggagttc caccatgagc tcacccgtgt ctatgacgca 1300

 aagatcacca gccatgtgcc ttagtgtcct tcttaacaga ctcaaaccac 1350

 atggaccacg aatattcttt ctgtccagaa gggctacttt ccacatatag 1400

 agctccaggg actgtctttt ctgtattcgc tgttcaataa acattgagtg 1450

 agcacctccc cagatggaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1500

 aaaa 1504

<210> 561
<211> 335
<212> PRT
<213> Homo sapien

<400> 561
 Met Trp Ala Thr Leu Pro Leu Leu Cys Ala Gly Ala Trp Leu Leu
   1               5                  10                  15

 Gly Val Pro Val Cys Gly Ala Ala Glu Leu Cys Val Asn Ser Leu
                  20                  25                  30

 Glu Lys Phe His Phe Lys Ser Trp Met Ser Lys His Arg Lys Thr
                  35                  40                  45

 Tyr Ser Thr Glu Glu Tyr His His Arg Leu Gln Thr Phe Ala Ser
                  50                  55                  60

 Asn Trp Arg Lys Ile Asn Ala His Asn Asn Gly Asn His Thr Phe
                  65                  70                  75

 Lys Met Ala Leu Asn Gln Phe Ser Asp Met Ser Phe Ala Glu Ile
                  80                  85                  90

 Lys His Lys Tyr Leu Trp Ser Glu Pro Gln Asn Cys Ser Ala Thr
                  95                 100                 105

 Lys Ser Asn Tyr Leu Arg Gly Thr Gly Pro Tyr Pro Pro Ser Val
                 110                 115                 120

 Asp Trp Arg Lys Lys Gly Asn Phe Val Ser Pro Val Lys Asn Gln
                 125                 130                 135

 Gly Ala Cys Gly Ser Cys Trp Thr Phe Ser Thr Thr Gly Ala Leu
                 140                 145                 150

 Glu Ser Ala Ile Ala Ile Ala Thr Gly Lys Met Leu Ser Leu Ala
                 155                 160                 165

 Glu Gln Gln Leu Val Asp Cys Ala Gln Asp Phe Asn Asn His Gly
                 170                 175                 180

 Cys Gln Gly Gly Leu Pro Ser Gln Ala Phe Glu Tyr Ile Leu Tyr
                 185                 190                 195

 Asn Lys Gly Ile Met Gly Glu Asp Thr Tyr Pro Tyr Gln Gly Lys
                 200                 205                 210

 Asp Gly Tyr Cys Lys Phe Gln Pro Gly Lys Ala Ile Gly Phe Val
                 215                 220                 225

 Lys Asp Val Ala Asn Ile Thr Ile Tyr Asp Glu Glu Ala Met Val
                 230                 235                 240

 Glu Ala Val Ala Leu Tyr Asn Pro Val Ser Phe Ala Phe Glu Val
                 245                 250                 255

 Thr Gln Asp Phe Met Met Tyr Arg Thr Gly Ile Tyr Ser Ser Thr
                 260                 265                 270

 Ser Cys His Lys Thr Pro Asp Lys Val Asn His Ala Val Leu Ala
                 275                 280                 285

 Val Gly Tyr Gly Glu Lys Asn Gly Ile Pro Tyr Trp Ile Val Lys
                 290                 295                 300

 Asn Ser Trp Gly Pro Gln Trp Gly Met Asn Gly Tyr Phe Leu Ile
                 305                 310                 315

 Glu Arg Gly Lys Asn Met Cys Gly Leu Ala Ala Cys Ala Ser Tyr
                 320                 325                 330

 Pro Ile Pro Leu Val
                 335

<210> 562
<211> 2960
<212> DNA
<213> Homo sapien

<400> 562
 ggcacgaggg tgtgcgtgat ggagaaaatt gggcaccagg gctgctcccg 50

 agattctcag atctgatttc cacgcttgct accaaaatag tctgggcagg 100

 ccacttttgg aagtaggcgt tatctagtga gcaggcggcc gctttcgatt 150

 tcgctttccc ctaaatggct gagcttctcg ccagcgcagg atcagcctgt 200

 tcctgggact ttccgagagc cccgccctcg ttccctcccc cagccgccag 250

 taggggagga ctcggcggta cccggagctt caggccccac cggggcgcgg 300

 agagtcccag gcccggccgg gaccgggacg gcgtccgagt gccaatggct 350

 agctctaggt gtcccgctcc ccgcgggtgc cgctgcctcc ccggagcttc 400

 tctcgcatgg ctggggacag tactgctact tctcgccgac tgggtgctgc 450

 tccggaccgc gctgccccgc atattctccc tgctggtgcc caccgcgctg 500

 ccactgctcc gggtctgggc ggtgggcctg agccgctggg ccgtgctctg 550

 gctgggggcc tgcggggtcc tcagggcaac ggttggctcc aagagcgaaa 600

 acgcaggtgc ccagggctgg ctggctgctt tgaagccatt agctgcggca 650

 ctgggcttgg ccctgccggg acttgccttg ttccgagagc tgatctcatg 700

 gggagccccc gggtccgcgg atagcaccag gctactgcac tggggaagtc 750

 accctaccgc cttcgttgtc agttatgcag cggcactgcc cgcagcagcc 800

 ctgtggcaca aactcgggag cctctgggtg cccggcggtc agggcggctc 850

 tggaaaccct gtgcgtcggc ttctaggctg cctgggctcg gagacgcgcc 900

 gcctctcgct gttcctggtc ctggtggtcc tctcctctct tggggagatg 950

 gccattccat tctttacggg ccgcctcact gactggattc tacaagatgg 1000

 ctcagccgat accttcactc gaaacttaac tctcatgtcc attctcacca 1050

 tagccagtgc agtgctggag ttcgtgggtg acgggatcta taacaacacc 1100

 atgggccacg tgcacagcca cttgcaggga gaggtgtttg gggctgtcct 1150

 gcgccaggag acggagtttt tccaacagaa ccagacaggt aacatcatgt 1200

 ctcgggtaac agaggacacg tccaccctga gtgattctct gagtgagaat 1250

 ctgagcttat ttctgtggta cctggtgcga ggcctatgtc tcttggggat 1300

 catgctctgg ggatcagtgt ccctcaccat ggtcaccctg atcaccctgc 1350

 ctctgctttt ccttctgccc aagaaggtgg gaaaatggta ccagttgctg 1400

 gaagtgcagg tgcgggaatc tctggcaaag tccagccagg tggccattga 1450

 ggctctgtcg gccatgccta cagttcgaag ctttgccaac gaggagggcg 1500

 aagcccagaa gtttagggaa aagctgcaag aaataaagac actcaaccag 1550

 aaggaggctg tggcctatgc agtcaactcc tggaccacta gtatttcagg 1600

 tatgctgctg aaagtgggaa tcctctacat tggtgggcag ctggtgacca 1650

 gtggggctgt aagcagtggg aaccttgtca catttgttct ctaccagatg 1700

 cagttcaccc aggctgtgga ggtactgctc tccatctacc ccagagtaca 1750

 gaaggctgtg ggctcctcag agaaaatatt tgagtacctg gaccgcaccc 1800

 ctcgctgccc acccagtggt ctgttgactc ccttacactt ggagggcctt 1850

 gtccagttcc aagatgtctc ctttgcctac ccaaaccgcc cagatgtctt 1900

 agtgctacag gggctgacat tcaccctacg ccctggcgag gtgacggcgc 1950

 tggtgggacc caatgggtct gggaagagca cagtggctgc cctgctgcag 2000

 aatctgtacc agcccaccgg gggacagctg ctgttggatg ggaagcccct 2050

 tccccaatat gagcaccgct acctgcacag gcaggtggct gcagtgggac 2100

 aagagccaca ggtatttgga agaagtcttc aagaaaatat tgcctatggc 2150

 ctgacccaga agccaactat ggaggaaatc acagctgctg cagtaaagtc 2200

 tggggcccat agtttcatct ctggactccc tcagggctat gacacagagg 2250

 tagacgaggc tgggagccag ctgtcagggg gtcagcgaca ggcagtggcg 2300

 ttggcccgag cattgatccg gaaaccgtgt gtacttatcc tggatgatgc 2350

 caccagtgcc ctggatgcaa acagccagtt acaggtggag cagctcctgt 2400

 acgaaagccc tgagcggtac tcccgctcag tgcttctcat cacccagcac 2450

 ctcagcctgg tggagcaggc tgaccacatc ctctttctgg aaggaggcgc 2500

 tatccgggag gggggaaccc accagcagct catggagaaa aaggggtgct 2550

 actgggccat ggtgcaggct cctgcagatg ctccagaatg aaagccttct 2600

 cagacctgcg cactccatct ccctcccttt tcttctctct gtggtggaga 2650

 accacagctg cagagtaggc agctgcctcc aggatgagtt acttgaaatt 2700

 tgccttgagt gtgttacctc ctttccaagc tcctcgtgat aatgcagact 2750

 tcctggagta caaacacagg atttgtaatt ccttactgta acggagttta 2800

 gagccagggc tgatgctttg gtgtggccag cactctgaaa ctgagaaatg 2850

 ttcagaatgt acggaaagat gatcagctat tttcaacata actgaaggca 2900

 tatgctggcc cataaacacc ctgtaggttc ttgatattta taataaaatt 2950

 ggtgttttgt 2960

<210> 563
<211> 808
<212> PRT
<213> Homo sapien

<400> 563
 Met Ala Glu Leu Leu Ala Ser Ala Gly Ser Ala Cys Ser Trp Asp
   1               5                  10                  15

 Phe Pro Arg Ala Pro Pro Ser Phe Pro Pro Pro Ala Ala Ser Arg
                  20                  25                  30

 Gly Gly Leu Gly Gly Thr Arg Ser Phe Arg Pro His Arg Gly Ala
                  35                  40                  45

 Glu Ser Pro Arg Pro Gly Arg Asp Arg Asp Gly Val Arg Val Pro
                  50                  55                  60

 Met Ala Ser Ser Arg Cys Pro Ala Pro Arg Gly Cys Arg Cys Leu
                  65                  70                  75

 Pro Gly Ala Ser Leu Ala Trp Leu Gly Thr Val Leu Leu Leu Leu
                  80                  85                  90

 Ala Asp Trp Val Leu Leu Arg Thr Ala Leu Pro Arg Ile Phe Ser
                  95                 100                 105

 Leu Leu Val Pro Thr Ala Leu Pro Leu Leu Arg Val Trp Ala Val
                 110                 115                 120

 Gly Leu Ser Arg Trp Ala Val Leu Trp Leu Gly Ala Cys Gly Val
                 125                 130                 135

 Leu Arg Ala Thr Val Gly Ser Lys Ser Glu Asn Ala Gly Ala Gln
                 140                 145                 150

 Gly Trp Leu Ala Ala Leu Lys Pro Leu Ala Ala Ala Leu Gly Leu
                 155                 160                 165

 Ala Leu Pro Gly Leu Ala Leu Phe Arg Glu Leu Ile Ser Trp Gly
                 170                 175                 180

 Ala Pro Gly Ser Ala Asp Ser Thr Arg Leu Leu His Trp Gly Ser
                 185                 190                 195

 His Pro Thr Ala Phe Val Val Ser Tyr Ala Ala Ala Leu Pro Ala
                 200                 205                 210

 Ala Ala Leu Trp His Lys Leu Gly Ser Leu Trp Val Pro Gly Gly
                 215                 220                 225

 Gln Gly Gly Ser Gly Asn Pro Val Arg Arg Leu Leu Gly Cys Leu
                 230                 235                 240

 Gly Ser Glu Thr Arg Arg Leu Ser Leu Phe Leu Val Leu Val Val
                 245                 250                 255

 Leu Ser Ser Leu Gly Glu Met Ala Ile Pro Phe Phe Thr Gly Arg
                 260                 265                 270

 Leu Thr Asp Trp Ile Leu Gln Asp Gly Ser Ala Asp Thr Phe Thr
                 275                 280                 285

 Arg Asn Leu Thr Leu Met Ser Ile Leu Thr Ile Ala Ser Ala Val
                 290                 295                 300

 Leu Glu Phe Val Gly Asp Gly Ile Tyr Asn Asn Thr Met Gly His
                 305                 310                 315

 Val His Ser His Leu Gln Gly Glu Val Phe Gly Ala Val Leu Arg
                 320                 325                 330

 Gln Glu Thr Glu Phe Phe Gln Gln Asn Gln Thr Gly Asn Ile Met
                 335                 340                 345

 Ser Arg Val Thr Glu Asp Thr Ser Thr Leu Ser Asp Ser Leu Ser
                 350                 355                 360

 Glu Asn Leu Ser Leu Phe Leu Trp Tyr Leu Val Arg Gly Leu Cys
                 365                 370                 375

 Leu Leu Gly Ile Met Leu Trp Gly Ser Val Ser Leu Thr Met Val
                 380                 385                 390

 Thr Leu Ile Thr Leu Pro Leu Leu Phe Leu Leu Pro Lys Lys Val
                 395                 400                 405

 Gly Lys Trp Tyr Gln Leu Leu Glu Val Gln Val Arg Glu Ser Leu
                 410                 415                 420

 Ala Lys Ser Ser Gln Val Ala Ile Glu Ala Leu Ser Ala Met Pro
                 425                 430                 435

 Thr Val Arg Ser Phe Ala Asn Glu Glu Gly Glu Ala Gln Lys Phe
                 440                 445                 450

 Arg Glu Lys Leu Gln Glu Ile Lys Thr Leu Asn Gln Lys Glu Ala
                 455                 460                 465

 Val Ala Tyr Ala Val Asn Ser Trp Thr Thr Ser Ile Ser Gly Met
                 470                 475                 480

 Leu Leu Lys Val Gly Ile Leu Tyr Ile Gly Gly Gln Leu Val Thr
                 485                 490                 495

 Ser Gly Ala Val Ser Ser Gly Asn Leu Val Thr Phe Val Leu Tyr
                 500                 505                 510

 Gln Met Gln Phe Thr Gln Ala Val Glu Val Leu Leu Ser Ile Tyr
                 515                 520                 525

 Pro Arg Val Gln Lys Ala Val Gly Ser Ser Glu Lys Ile Phe Glu
                 530                 535                 540

 Tyr Leu Asp Arg Thr Pro Arg Cys Pro Pro Ser Gly Leu Leu Thr
                 545                 550                 555

 Pro Leu His Leu Glu Gly Leu Val Gln Phe Gln Asp Val Ser Phe
                 560                 565                 570

 Ala Tyr Pro Asn Arg Pro Asp Val Leu Val Leu Gln Gly Leu Thr
                 575                 580                 585

 Phe Thr Leu Arg Pro Gly Glu Val Thr Ala Leu Val Gly Pro Asn
                 590                 595                 600

 Gly Ser Gly Lys Ser Thr Val Ala Ala Leu Leu Gln Asn Leu Tyr
                 605                 610                 615

 Gln Pro Thr Gly Gly Gln Leu Leu Leu Asp Gly Lys Pro Leu Pro
                 620                 625                 630

 Gln Tyr Glu His Arg Tyr Leu His Arg Gln Val Ala Ala Val Gly
                 635                 640                 645

 Gln Glu Pro Gln Val Phe Gly Arg Ser Leu Gln Glu Asn Ile Ala
                 650                 655                 660

 Tyr Gly Leu Thr Gln Lys Pro Thr Met Glu Glu Ile Thr Ala Ala
                 665                 670                 675

 Ala Val Lys Ser Gly Ala His Ser Phe Ile Ser Gly Leu Pro Gln
                 680                 685                 690

 Gly Tyr Asp Thr Glu Val Asp Glu Ala Gly Ser Gln Leu Ser Gly
                 695                 700                 705

 Gly Gln Arg Gln Ala Val Ala Leu Ala Arg Ala Leu Ile Arg Lys
                 710                 715                 720

 Pro Cys Val Leu Ile Leu Asp Asp Ala Thr Ser Ala Leu Asp Ala
                 725                 730                 735

 Asn Ser Gln Leu Gln Val Glu Gln Leu Leu Tyr Glu Ser Pro Glu
                 740                 745                 750

 Arg Tyr Ser Arg Ser Val Leu Leu Ile Thr Gln His Leu Ser Leu
                 755                 760                 765

 Val Glu Gln Ala Asp His Ile Leu Phe Leu Glu Gly Gly Ala Ile
                 770                 775                 780

 Arg Glu Gly Gly Thr His Gln Gln Leu Met Glu Lys Lys Gly Cys
                 785                 790                 795

 Tyr Trp Ala Met Val Gln Ala Pro Ala Asp Ala Pro Glu
                 800                 805

<210> 564
<211> 3960
<212> DNA
<213> Homo sapien

<400> 564
 gttctgaatg atgactgacg cgggtttggg tgatacccct cacagcccct 50

 gtcattccgg agtcataagg cacccgcgcg tctagcccca gcgccagggc 100

 acgcgagcgg cgctggaggg aggaaagctt ccgcctgcgg gccggacaaa 150

 agtcccgcct gcccacggct ttttgcccgc cgctcgtgac cgagacgcct 200

 cgccgcggcc agctcgctgc tctcgctggc ggatggtgtg tggccgccgc 250

 aggacgcccg ccgtgcccgg gccatgaagt agcggctgct ggcggcgccg 300

 ctgcccaacc gccagcccca gccccgcgct gcgctgcccg gtcctctccc 350

 ggcggggtcg tatcggcgtg gacatggctg gccgcgtccc tagcctgcta 400

 gttctccttg tttttccaag cagctgtttg gctttccgaa gcccactttc 450

 tgtctttaag aggtttaaag aaactaccag accattttcc aatgaatgtc 500

 ttggtaccac cagacccgta gttcctattg attcatcaga ttttgcattg 550

 gatattcgca tgcctggggt tacacctaaa cagtccgata catacttctg 600

 catgtctatg cgaataccag tggatgagga agccttcgtg attgacttca 650

 agcctcgagc cagcatggat actgtccatc acatgttact ttttggatgc 700

 aatatgcctt catccactgg aagttactgg ttttgtgatg aaggaacctg 750

 tacagataaa gccaatattc tgtatgcctg ggcgagaaat gctcccccta 800

 cccggctccc caaaggtgtt ggattcagag ttggaggaga gactggaagt 850

 aaatactttg tactacaggt acactatggg gatattagtg cttttagaga 900

 taataacaag gactgttctg gtgtgtcctt acacctcaca cgtctgccac 950

 agcctttaat tgctggcatg taccttatga tgtctgttga cactgttatc 1000

 ccagcaggag aaaaagtggt gaattctgac atttcatgcc attataaaaa 1050

 ttatccaatg catgtctttg cctatagagt tcacactcac catttaggta 1100

 aggtagtaag tggatacaga gtaagaaatg gacagtggac actgattgga 1150

 cggcagagcc ctcagctgcc acaggctttc taccctgtgg ggcatccagt 1200

 tgatgtaagt tttggtgacc tactggctgc aagatgtgta ttcactggtg 1250

 aaggaaggac agaagccaca cacattggtg gcacgtctag tgatgaaatg 1300

 tgcaacttat acattatgta ttacatggaa gccaagcatg cagtttcttt 1350

 catgacctgt acccagaatg tagctccaga tatgttcaga accataccac 1400

 cagaggccaa cattccaatt cccgtgaagt ctgatatggt tatgatgcat 1450

 gaacatcata aagaaacaga atataaagat aagattcctt tactacagca 1500

 gccaaaacga gaagaagaag aagtgttaga ccagggtgat ttctattcac 1550

 tactttccaa gctgctagga gaaagggaag atgttgttca tgtgcacaaa 1600

 tataatccta cagaaaaggc agaatcagag tcagacctgg tagctgagat 1650

 tgcaaatgta gtccaaaaaa aggatcttgg tcgatctgat gccagagagg 1700

 gtgcagaaca tgagaggggt aatgctattc ttgtcagaga cagaattcac 1750

 aaattccaca gactagtatc taccttgagg ccaccagaga gcagagtttt 1800

 ctcattacag cagcccccac ctggtgaagg cacctgggaa ccagaacaca 1850

 caggagattt ccacatggaa gaggcactgg attggcctgg agtatacttg 1900

 ttaccaggcc aggtttctgg ggtggctcta gaccctaaga ataacctggt 1950

 gattttccac agaggtgacc atgtctggga tggaaactcg tttgacagca 2000

 agtttgttta ccagcaaata ggactcggac caattgaaga agacactatt 2050

 cttgtcatag atccaaataa tgctgcagta ctccagtcca gtggaaaaaa 2100

 tctgttttac ttgccacatg gcttgagtat agataaagat gggaattatt 2150

 gggtcacaga cgtggctctc catcaggtgt tcaaactgga tccaaacaat 2200

 aaagaaggcc ctgtattaat cctgggaagg agcatgcaac caggcagtga 2250

 ccagaatcac ttctgtcaac ccactgatgt ggctgtggat ccaggcactg 2300

 gagccattta tgtatcagat ggttactgca acagcaggat tgtgcagttt 2350

 tcaccaagtg gaaagttcat cacacagtgg ggagaagagt cttcagggag 2400

 cagtcctctg ccaggccagt tcactgttcc tcacagcttg gctcttgtgc 2450

 ctcttttggg ccaattatgt gtggcagacc gggaaaatgg tcggatccag 2500

 tgttttaaaa ctgacaccaa agaatttgtg agagagatta agcattcatc 2550

 atttggaaga aatgtatttg caatttcata tataccaggc ttgctctttg 2600

 cagtgaatgg gaagcctcat tttggggacc aagaacctgt acaaggattt 2650

 gtgatgaact tttccaatgg ggaaattata gacatcttca agccagtgcg 2700

 caagcacttt gatatgcctc atgatattgt tgcatctgaa gatgggactg 2750

 tgtacattgg agatgctcat accaacaccg tgtggaagtt caccttgact 2800

 gagaaattgg aacatcgatc agttaaaaag gctggcattg aggtccagga 2850

 aatcaaagaa gccgaggcag ttgttgaaac caaaatggag aacaaaccca 2900

 cctcctcaga attgcagaag atgcaagaga aacagaaact gatcaaagag 2950

 ccaggctcgg gagtgcctgt tgttctcatt acaacccttc tggttattcc 3000

 ggtggttgtc ctgctggcca ttgccatatt tattcggtgg aaaaaatcaa 3050

 gggcctttgg agcagattct gaacacaaac tcgagacgag ttcaggaaga 3100

 gtactgggaa gatttagagg aaagggaagt ggaggcttaa accttggtaa 3150

 tttctttgca agccgtaagg gctacagtcg aaaagggttt gaccggctta 3200

 gcactgaggg cagtgaccaa gagaaagagg atgatggaag tgaatcagaa 3250

 gaggagtatt cagcacctct gcctgcgctc gcaccttcct cctcctgaaa 3300

 accaagcttt gatttagatt gagtaagatt tacccagaat gtcagattcc 3350

 tttcccttta gcacgtttaa agttctgtgt atttaattgt aaactgtact 3400

 agtctgtgtg ggactgtaca cactttattt acttcgtttt ggttaagttg 3450

 gcttctgttt ctagttgagg agtttcctaa aagttcataa cagtgccatt 3500

 gtctttatat gaacatagac tagagaaacc gtcctctttt tccatcataa 3550

 ttctaatcta acaatggaag atttgcccat ttacactttt gagacttttt 3600

 ggtggatgta aataacccca ttctttgctt gaacacagta ttttcccaat 3650

 agcactttca ttgccagtgt ctttctttgg tgcctttcct gttcagcatt 3700

 cttagcctgt ggcagtaaag agaaactttg tgctacatga cgacaaagct 3750

 gctaaatctc ctattttttt aaaatcacta acattatatt gcaatgaagg 3800

 aaataaaaaa gtctctattt aaattctttt ttaaattttc ttcagttggt 3850

 gtgtttttgg gatgtcttat ttttagatgg ttacactgtt agaacactat 3900

 tttcagaatc tgaatgtaat ttgtgtaata aagtgttttc agagcaaaaa 3950

 aaaaaaaaaa 3960

<210> 565
<211> 974
<212> PRT
<213> Homo sapien

<400> 565
 Met Ala Gly Arg Val Pro Ser Leu Leu Val Leu Leu Val Phe Pro
   1               5                  10                  15

 Ser Ser Cys Leu Ala Phe Arg Ser Pro Leu Ser Val Phe Lys Arg
                  20                  25                  30

 Phe Lys Glu Thr Thr Arg Pro Phe Ser Asn Glu Cys Leu Gly Thr
                  35                  40                  45

 Thr Arg Pro Val Val Pro Ile Asp Ser Ser Asp Phe Ala Leu Asp
                  50                  55                  60

 Ile Arg Met Pro Gly Val Thr Pro Lys Gln Ser Asp Thr Tyr Phe
                  65                  70                  75

 Cys Met Ser Met Arg Ile Pro Val Asp Glu Glu Ala Phe Val Ile
                  80                  85                  90

 Asp Phe Lys Pro Arg Ala Ser Met Asp Thr Val His His Met Leu
                  95                 100                 105

 Leu Phe Gly Cys Asn Met Pro Ser Ser Thr Gly Ser Tyr Trp Phe
                 110                 115                 120

 Cys Asp Glu Gly Thr Cys Thr Asp Lys Ala Asn Ile Leu Tyr Ala
                 125                 130                 135

 Trp Ala Arg Asn Ala Pro Pro Thr Arg Leu Pro Lys Gly Val Gly
                 140                 145                 150

 Phe Arg Val Gly Gly Glu Thr Gly Ser Lys Tyr Phe Val Leu Gln
                 155                 160                 165

 Val His Tyr Gly Asp Ile Ser Ala Phe Arg Asp Asn Asn Lys Asp
                 170                 175                 180

 Cys Ser Gly Val Ser Leu His Leu Thr Arg Leu Pro Gln Pro Leu
                 185                 190                 195

 Ile Ala Gly Met Tyr Leu Met Met Ser Val Asp Thr Val Ile Pro
                 200                 205                 210

 Ala Gly Glu Lys Val Val Asn Ser Asp Ile Ser Cys His Tyr Lys
                 215                 220                 225

 Asn Tyr Pro Met His Val Phe Ala Tyr Arg Val His Thr His His
                 230                 235                 240

 Leu Gly Lys Val Val Ser Gly Tyr Arg Val Arg Asn Gly Gln Trp
                 245                 250                 255

 Thr Leu Ile Gly Arg Gln Ser Pro Gln Leu Pro Gln Ala Phe Tyr
                 260                 265                 270

 Pro Val Gly His Pro Val Asp Val Ser Phe Gly Asp Leu Leu Ala
                 275                 280                 285

 Ala Arg Cys Val Phe Thr Gly Glu Gly Arg Thr Glu Ala Thr His
                 290                 295                 300

 Ile Gly Gly Thr Ser Ser Asp Glu Met Cys Asn Leu Tyr Ile Met
                 305                 310                 315

 Tyr Tyr Met Glu Ala Lys His Ala Val Ser Phe Met Thr Cys Thr
                 320                 325                 330

 Gln Asn Val Ala Pro Asp Met Phe Arg Thr Ile Pro Pro Glu Ala
                 335                 340                 345

 Asn Ile Pro Ile Pro Val Lys Ser Asp Met Val Met Met His Glu
                 350                 355                 360

 His His Lys Glu Thr Glu Tyr Lys Asp Lys Ile Pro Leu Leu Gln
                 365                 370                 375

 Gln Pro Lys Arg Glu Glu Glu Glu Val Leu Asp Gln Gly Asp Phe
                 380                 385                 390

 Tyr Ser Leu Leu Ser Lys Leu Leu Gly Glu Arg Glu Asp Val Val
                 395                 400                 405

 His Val His Lys Tyr Asn Pro Thr Glu Lys Ala Glu Ser Glu Ser
                 410                 415                 420

 Asp Leu Val Ala Glu Ile Ala Asn Val Val Gln Lys Lys Asp Leu
                 425                 430                 435

 Gly Arg Ser Asp Ala Arg Glu Gly Ala Glu His Glu Arg Gly Asn
                 440                 445                 450

 Ala Ile Leu Val Arg Asp Arg Ile His Lys Phe His Arg Leu Val
                 455                 460                 465

 Ser Thr Leu Arg Pro Pro Glu Ser Arg Val Phe Ser Leu Gln Gln
                 470                 475                 480

 Pro Pro Pro Gly Glu Gly Thr Trp Glu Pro Glu His Thr Gly Asp
                 485                 490                 495

 Phe His Met Glu Glu Ala Leu Asp Trp Pro Gly Val Tyr Leu Leu
                 500                 505                 510

 Pro Gly Gln Val Ser Gly Val Ala Leu Asp Pro Lys Asn Asn Leu
                 515                 520                 525

 Val Ile Phe His Arg Gly Asp His Val Trp Asp Gly Asn Ser Phe
                 530                 535                 540

 Asp Ser Lys Phe Val Tyr Gln Gln Ile Gly Leu Gly Pro Ile Glu
                 545                 550                 555

 Glu Asp Thr Ile Leu Val Ile Asp Pro Asn Asn Ala Ala Val Leu
                 560                 565                 570

 Gln Ser Ser Gly Lys Asn Leu Phe Tyr Leu Pro His Gly Leu Ser
                 575                 580                 585

 Ile Asp Lys Asp Gly Asn Tyr Trp Val Thr Asp Val Ala Leu His
                 590                 595                 600

 Gln Val Phe Lys Leu Asp Pro Asn Asn Lys Glu Gly Pro Val Leu
                 605                 610                 615

 Ile Leu Gly Arg Ser Met Gln Pro Gly Ser Asp Gln Asn His Phe
                 620                 625                 630

 Cys Gln Pro Thr Asp Val Ala Val Asp Pro Gly Thr Gly Ala Ile
                 635                 640                 645

 Tyr Val Ser Asp Gly Tyr Cys Asn Ser Arg Ile Val Gln Phe Ser
                 650                 655                 660

 Pro Ser Gly Lys Phe Ile Thr Gln Trp Gly Glu Glu Ser Ser Gly
                 665                 670                 675

 Ser Ser Pro Leu Pro Gly Gln Phe Thr Val Pro His Ser Leu Ala
                 680                 685                 690

 Leu Val Pro Leu Leu Gly Gln Leu Cys Val Ala Asp Arg Glu Asn
                 695                 700                 705

 Gly Arg Ile Gln Cys Phe Lys Thr Asp Thr Lys Glu Phe Val Arg
                 710                 715                 720

 Glu Ile Lys His Ser Ser Phe Gly Arg Asn Val Phe Ala Ile Ser
                 725                 730                 735

 Tyr Ile Pro Gly Leu Leu Phe Ala Val Asn Gly Lys Pro His Phe
                 740                 745                 750

 Gly Asp Gln Glu Pro Val Gln Gly Phe Val Met Asn Phe Ser Asn
                 755                 760                 765

 Gly Glu Ile Ile Asp Ile Phe Lys Pro Val Arg Lys His Phe Asp
                 770                 775                 780

 Met Pro His Asp Ile Val Ala Ser Glu Asp Gly Thr Val Tyr Ile
                 785                 790                 795

 Gly Asp Ala His Thr Asn Thr Val Trp Lys Phe Thr Leu Thr Glu
                 800                 805                 810

 Lys Leu Glu His Arg Ser Val Lys Lys Ala Gly Ile Glu Val Gln
                 815                 820                 825

 Glu Ile Lys Glu Ala Glu Ala Val Val Glu Thr Lys Met Glu Asn
                 830                 835                 840

 Lys Pro Thr Ser Ser Glu Leu Gln Lys Met Gln Glu Lys Gln Lys
                 845                 850                 855

 Leu Ile Lys Glu Pro Gly Ser Gly Val Pro Val Val Leu Ile Thr
                 860                 865                 870

 Thr Leu Leu Val Ile Pro Val Val Val Leu Leu Ala Ile Ala Ile
                 875                 880                 885

 Phe Ile Arg Trp Lys Lys Ser Arg Ala Phe Gly Ala Asp Ser Glu
                 890                 895                 900

 His Lys Leu Glu Thr Ser Ser Gly Arg Val Leu Gly Arg Phe Arg
                 905                 910                 915

 Gly Lys Gly Ser Gly Gly Leu Asn Leu Gly Asn Phe Phe Ala Ser
                 920                 925                 930

 Arg Lys Gly Tyr Ser Arg Lys Gly Phe Asp Arg Leu Ser Thr Glu
                 935                 940                 945

 Gly Ser Asp Gln Glu Lys Glu Asp Asp Gly Ser Glu Ser Glu Glu
                 950                 955                 960

 Glu Tyr Ser Ala Pro Leu Pro Ala Leu Ala Pro Ser Ser Ser
                 965                 970

<210> 566
<211> 662
<212> DNA
<213> Homo sapien

<400> 566
 accgccgacg cagacccctc tctgcacgcc agcccgcccg cacccaccat 50

 ggccacagtt cagcagctgg aaggaagatg gcgcctggtg gacagcaaag 100

 gctttgatga atacatgaag gagctaggag tgggaatagc tttgcgaaaa 150

 atgggcgcaa tggccaagcc agattgtatc atcacttgtg atggtaaaaa 200

 cctcaccata aaaactgaga gcactttgaa aacaacacag ttttcttgta 250

 ccctgggaga gaagtttgaa gaaaccacag ctgatggcag aaaaactcag 300

 actgtctgca actttacaga tggtgcattg gttcagcatc aggagtggga 350

 tgggaaggaa agcacaataa caagaaaatt gaaagatggg aaattagtgg 400

 tggagtgtgt catgaacaat gtcacctgta ctcggatcta tgaaaaagta 450

 gaataaaaat tccatcatca ctttggacag gagttaatta agagaatgac 500

 caagctcagt tcaatgagca aatctccata ctgtttcttt cttttttttt 550

 tcattactgt gttcaattat ctttatcata aacattttac atgcagctat 600

 ttcaaagtgt gttggattaa ttaggatcat ccctttggtt aataaataaa 650

 tgtgtttgtg ct 662

<210> 567
<211> 135
<212> PRT
<213> Homo sapien

<400> 567
 Met Ala Thr Val Gln Gln Leu Glu Gly Arg Trp Arg Leu Val Asp
   1               5                  10                  15

 Ser Lys Gly Phe Asp Glu Tyr Met Lys Glu Leu Gly Val Gly Ile
                  20                  25                  30

 Ala Leu Arg Lys Met Gly Ala Met Ala Lys Pro Asp Cys Ile Ile
                  35                  40                  45

 Thr Cys Asp Gly Lys Asn Leu Thr Ile Lys Thr Glu Ser Thr Leu
                  50                  55                  60

 Lys Thr Thr Gln Phe Ser Cys Thr Leu Gly Glu Lys Phe Glu Glu
                  65                  70                  75

 Thr Thr Ala Asp Gly Arg Lys Thr Gln Thr Val Cys Asn Phe Thr
                  80                  85                  90

 Asp Gly Ala Leu Val Gln His Gln Glu Trp Asp Gly Lys Glu Ser
                  95                 100                 105

 Thr Ile Thr Arg Lys Leu Lys Asp Gly Lys Leu Val Val Glu Cys
                 110                 115                 120

 Val Met Asn Asn Val Thr Cys Thr Arg Ile Tyr Glu Lys Val Glu
                 125                 130                 135

<210> 568
<211> 3592
<212> DNA
<213> Homo sapien

<400> 568
 ctgagcgggt gcgcgggcaa cttccggtgt gggtgacgag tggtggccga 50

 agcaggggga cagcaaggga cgctcaggcg gggaccatgg cggacggcgg 100

 ctcggagcgg gctgacgggc gcatcgtcaa gatggaggtg gactacagcg 150

 ccacggtgga tcagcgccta cccgagtgtg cgaagctagc caaggaagga 200

 agacttcaag aagtcattga aacccttctc tctctggaaa agcagactcg 250

 tactgcttcc gatatggtat cgacatcccg tatcttagtt gcagtagtga 300

 agatgtgcta tgaggctaaa gaatgggatt tacttaatga aaatattatg 350

 cttttgtcca aaaggcggag tcagttaaaa caagctgttg ccaaaatggt 400

 tcaacagtgc tgtacttatg ttgaggaaat cacagacctt cctatcaaac 450

 ttcgattaat tgatactcta cgaatggtta ccgaaggcaa gatttatgtt 500

 gaaattgagc gtgcgcgact gactaaaaca ttagcaacta taaaagaaca 550

 aaatggtgat gtgaaagagg cagcctccat tttacaggag ttacaggtgg 600

 aaacctacgg gtcaatggaa aagaaagagc gagtggaatt tattttggag 650

 caaatgaggc tctgcctagc tgtgaaggat tacattcgaa cacaaatcat 700

 cagcaagaaa attaacacca aatttttcca ggaagaaaat acagagaaat 750

 taaagttgaa gtactataat ttaatgattc agctggatca acatgaggga 800

 tcctatttgt ctatttgtaa gcactacaga gcaatatatg atactccctg 850

 tatacaggca gaaagtgaaa aatggcagca ggctctgaag agtgttgtac 900

 tctatgttat cctggctcct tttgacaatg aacagtcaga tttggttcac 950

 cgaataagtg gtgacaagaa gttagaagaa attcccaaat acaaggatct 1000

 tttaaagctt tttaccacaa tggagttgat gcgttggtcc acacttgttg 1050

 aggactatgg aatggaatta agaaaaggtt cccttgagag tcctgcaacg 1100

 gatgtttttg gttctacaga ggaaggtgaa aaaaggtgga aagacttgaa 1150

 gaacagagtt gttgaacata atattagaat aatggccaag tattatactc 1200

 ggataacaat gaaaaggatg gcacagcttc tggatctatc tgttgatgag 1250

 tccgaagcct ttctctcaaa tctagtagtt aacaagacca tctttgctaa 1300

 agtagacaga ttagcaggaa ttatcaactt ccagagaccc aaggatccaa 1350

 ataatttatt aaatgactgg tctcagaaac tgaactcatt aatgtctctg 1400

 gttaacaaaa ctacgcatct catagccaaa gaggagatga tacataatct 1450

 acaataaggg tcttagtgct ttagaaaaaa gttaaaattg gaagtcatta 1500

 aaaaaagact gttataatgg tgtatatgtt ggggtttttt ttctaagctt 1550

 ctttgtctta aattttaaaa tagtgaatat gtttgagact ccctttgacc 1600

 tttcagttcc ccaagttcat tgttaacttt gcatttgcaa ttggtgcaaa 1650

 aatacagatt tctgtcgtct gaatacacaa aaagttgtgt cataacttac 1700

 ccagatatgt ttttctatca tttgaaacct ttttagctac tgtttgtttt 1750

 cattcaacta acaaacatat tccaataata aaagcagtat atacatattt 1800

 cctttctaca gttacctctg attctcaaca ttttgtgggg tagtgatttg 1850

 gcaagtgttt tttaaataaa acaaatctca ttgtaaagct atcagtcatt 1900

 tagtagaata gaaaagcaac atagagcata caagaacatt tgggatagag 1950

 ttgtgatttg tgaagaattt gtactttgat attgtggcgg aaagtctaga 2000

 ctgagtgtgt atgctggtaa actgtagact tttttttttt tttttttgag 2050

 tccggctggt tccaatcaca gtagcttgat tgctttcagc cctcatcctc 2100

 tcacttgatc agttgttcaa cagaatcagc tgacataatt gacacagttt 2150

 attgggtgtt aagtccgctc tatagggata gtgactactt tttttttttt 2200

 tttttttttg ctcttcttcc tctccccttt ctttatatgg gtttaaattt 2250

 aacataaagt tgtttttata aggcttattt gtggctttaa cttgtaagtc 2300

 tgattacatc attattgttc caaattcatt atctctgtag gaacttttag 2350

 ttccattata tgaacactgg ataacctaat tttttttaat gctttaaaaa 2400

 aatggcaaaa agacgtcagg ccaccctcat agtaagtggt gtagtattaa 2450

 aatattttca cggaattaaa agtagcttgc tgtcaaagaa acacctgaga 2500

 tgaattggtg tgaacgaatt ttgcaagttt aatttgattt atttcagaga 2550

 aaatagaaaa aacaatgtta gaaggttatt taaaatgata cttaaataaa 2600

 gaaagtgtga ggtctacttt aaaaaaattc aaatgaagag aaaaagaaaa 2650

 acagcattct agaaatggca tttctcctaa ttaattttcc acttaatgga 2700

 agattatcaa ttgtcctatt ttatgatccc aggactgaag acagttgtgg 2750

 gatatctgtc atatttatcc tgtgagtcat tgtgaataat gacatacagt 2800

 actgaagtaa tctgatttta ttctttggaa attcaatgca ttggtcacac 2850

 taataacatc aacatctgct atcacttatc tttttaaaac taaccaaaaa 2900

 aggctgggat tacaggcatg agccactgca cccaactcct ctttcgtctt 2950

 tctttaacac acactaggct ctttgtgtat tatgattcag tgctatttgt 3000

 aactgtgtcc cagtgaccaa attgcactcg actcgatcag ctgttcatcc 3050

 atttcgtgtt ttttcctgtc aaacattaat ccagcaaata tatgaggtat 3100

 ttaccaattt attttcttag tattacaaaa taattcatta gcataaagta 3150

 caatagtgaa atatttgagt tgttcggaac ctcaattaat cctgttttac 3200

 atttcagacc taaagctggc aatcaggaga agaagcactt tgttttaaat 3250

 gtggagaaga taacacttga ttccatttca ttgtcattag tgtattaacc 3300

 agcaggagag gtgatgagcc atttttcaaa tgaaatacct tttatttcca 3350

 tataattttt ttattttaga gttcaatagc tgtttctatg attatcctca 3400

 atttccatat gttactgaat ctgaaaaaca tctttaaaat tcaaacagtt 3450

 ccattttctc tcttgtaagt gttaaatgtg ataaaagtac atattttaaa 3500

 ttgttttcag ctcttggata tagcagcaat aaaaacacta atttgtgggt 3550

 atttaagaaa acctggagaa taaactcata ctttaaaaga tc 3592

<210> 569
<211> 456
<212> PRT
<213> Homo sapien

<400> 569
 Met Ala Asp Gly Gly Ser Glu Arg Ala Asp Gly Arg Ile Val Lys
   1               5                  10                  15

 Met Glu Val Asp Tyr Ser Ala Thr Val Asp Gln Arg Leu Pro Glu
                  20                  25                  30

 Cys Ala Lys Leu Ala Lys Glu Gly Arg Leu Gln Glu Val Ile Glu
                  35                  40                  45

 Thr Leu Leu Ser Leu Glu Lys Gln Thr Arg Thr Ala Ser Asp Met
                  50                  55                  60

 Val Ser Thr Ser Arg Ile Leu Val Ala Val Val Lys Met Cys Tyr
                  65                  70                  75

 Glu Ala Lys Glu Trp Asp Leu Leu Asn Glu Asn Ile Met Leu Leu
                  80                  85                  90

 Ser Lys Arg Arg Ser Gln Leu Lys Gln Ala Val Ala Lys Met Val
                  95                 100                 105

 Gln Gln Cys Cys Thr Tyr Val Glu Glu Ile Thr Asp Leu Pro Ile
                 110                 115                 120

 Lys Leu Arg Leu Ile Asp Thr Leu Arg Met Val Thr Glu Gly Lys
                 125                 130                 135

 Ile Tyr Val Glu Ile Glu Arg Ala Arg Leu Thr Lys Thr Leu Ala
                 140                 145                 150

 Thr Ile Lys Glu Gln Asn Gly Asp Val Lys Glu Ala Ala Ser Ile
                 155                 160                 165

 Leu Gln Glu Leu Gln Val Glu Thr Tyr Gly Ser Met Glu Lys Lys
                 170                 175                 180

 Glu Arg Val Glu Phe Ile Leu Glu Gln Met Arg Leu Cys Leu Ala
                 185                 190                 195

 Val Lys Asp Tyr Ile Arg Thr Gln Ile Ile Ser Lys Lys Ile Asn
                 200                 205                 210

 Thr Lys Phe Phe Gln Glu Glu Asn Thr Glu Lys Leu Lys Leu Lys
                 215                 220                 225

 Tyr Tyr Asn Leu Met Ile Gln Leu Asp Gln His Glu Gly Ser Tyr
                 230                 235                 240

 Leu Ser Ile Cys Lys His Tyr Arg Ala Ile Tyr Asp Thr Pro Cys
                 245                 250                 255

 Ile Gln Ala Glu Ser Glu Lys Trp Gln Gln Ala Leu Lys Ser Val
                 260                 265                 270

 Val Leu Tyr Val Ile Leu Ala Pro Phe Asp Asn Glu Gln Ser Asp
                 275                 280                 285

 Leu Val His Arg Ile Ser Gly Asp Lys Lys Leu Glu Glu Ile Pro
                 290                 295                 300

 Lys Tyr Lys Asp Leu Leu Lys Leu Phe Thr Thr Met Glu Leu Met
                 305                 310                 315

 Arg Trp Ser Thr Leu Val Glu Asp Tyr Gly Met Glu Leu Arg Lys
                 320                 325                 330

 Gly Ser Leu Glu Ser Pro Ala Thr Asp Val Phe Gly Ser Thr Glu
                 335                 340                 345

 Glu Gly Glu Lys Arg Trp Lys Asp Leu Lys Asn Arg Val Val Glu
                 350                 355                 360

 His Asn Ile Arg Ile Met Ala Lys Tyr Tyr Thr Arg Ile Thr Met
                 365                 370                 375

 Lys Arg Met Ala Gln Leu Leu Asp Leu Ser Val Asp Glu Ser Glu
                 380                 385                 390

 Ala Phe Leu Ser Asn Leu Val Val Asn Lys Thr Ile Phe Ala Lys
                 395                 400                 405

 Val Asp Arg Leu Ala Gly Ile Ile Asn Phe Gln Arg Pro Lys Asp
                 410                 415                 420

 Pro Asn Asn Leu Leu Asn Asp Trp Ser Gln Lys Leu Asn Ser Leu
                 425                 430                 435

 Met Ser Leu Val Asn Lys Thr Thr His Leu Ile Ala Lys Glu Glu
                 440                 445                 450

 Met Ile His Asn Leu Gln
                 455

<210> 570
<211> 4464
<212> DNA
<213> Homo sapien

<400> 570
 agataatctg aatgctggct ggggcagaaa attactaaga tcctgtggaa 50

 gtgtgaggat tattaaactg atcactgtct gataaggtga gatcaaattg 100

 ggaatgcttt cataatgaac gtcaaccagt cagttccacc tgtgccacca 150

 tttgggcagc cccagcccat ctacccaggg tatcatcagt ccagctatgg 200

 tgggcaatca gggtccacag cccccgccat tccctatgga gcctacaatg 250

 gcccagtacc aggctatcag caaacacctc cccaaggtat gtcaagagcc 300

 ccaccttcct cgggggcacc tccagcctca acagcacagg ctccttgtgg 350

 ccaggctgca tatggccagt ttggccaagg agatgtacag aatgggccaa 400

 gctccactgt tcagatgcaa aggctgcctg ggtctcagcc atttgggtcc 450

 ccattggccc ctgtgggcaa ccagccacct gtgcttcagc cctatggccc 500

 tcccccgaca agtgcacagg tggctacgca gctgtctgga atgcagatca 550

 gcggtgctgt ggccccagcc cctccttctt cagggctggg ctttggccca 600

 ccaacatcgc tggcttcagc ctcaggaagt ttccctaact ctggtctgta 650

 tggctcctat cctcagggcc aggctcctcc ccttagccag gcccaaggtc 700

 atcctgggat ccagactccc cagcgatctg ccccatcaca ggcctccagc 750

 ttcacacccc cagcttcagg gggtcctcgg ctgccttcga tgactggtcc 800

 actcctgcct ggacagagtt ttggagggcc ctcagtgagc cagcccaacc 850

 atgtgtcttc acctcctcaa gctctgcccc ctggcaccca gatgactggg 900

 cccctgggac cactgccacc tatgcactcc ccgcagcagc caggctatca 950

 gccccaacaa aatggttcct tcggaccagc ccggggccct cagtctaatt 1000

 atggaggccc ctacccagca gcacccacct ttggcagtca gcctgggcct 1050

 cctcagccac tgcctcctaa gcgcctggac cctgatgcca tcccaagccc 1100

 tattcaggtc attgaagatg acaggaacaa ccggggtaca gagccatttg 1150

 ttactggagt acggggccag gtgccaccct tagtcactac caacttcctg 1200

 gtgaaagacc aagggaatgc aagtccccga tacatccgat gtacatccta 1250

 taatatccct tgcacatctg acatggctaa gcaggctcag gtgcccctgg 1300

 cagcagtcat caaaccgctg gcaaggctgc ccccagagga ggcttcaccg 1350

 tatgttgtgg accatgggga atctggccct ttgcgctgca accgctgcaa 1400

 agcatacatg tgtcccttca tgcagttcat tgaaggaggg aggcgtttcc 1450

 agtgctgttt ttgcagctgt atcaatgatg ttccccccca gtattttcag 1500

 cacctggatc ataccggcaa acgtgtggat gcttatgacc gccctgagct 1550

 atccctgggc tcttatgaat tcttggccac tgtagattac tgcaagaaca 1600

 ataagttccc cagccctcct gcctttatct tcatgattga cgtctcctac 1650

 aatgccatca ggactggtct tgttaggctc ctctgtgagg agctcaagtc 1700

 actgttagac tttctaccta gggagggtgg ggcagaagag tcagcaatcc 1750

 gcgttggctt tgtcacctac aataaggtgc tccacttcta taatgtgaag 1800

 agctcattgg cccagccaca gatgatggtt gtgtctgatg tggctgacat 1850

 gtttgtgcca ctgctggatg gcttcctggt caacgtcaat gagtctcggg 1900

 cagttatcac cagcttattg gatcagattc cagaaatgtt tgcagacaca 1950

 agggaaacag agacagtatt tgtaccagtt atccaggctg gaatggaggc 2000

 tctgaaggct gctgagtgtg cagggaagct ctttctattc catacatccc 2050

 tgcccattgc agaggcccca gggaaactga agaacagaga tgacaggaag 2100

 ctgatcaata cagacaagga gaagactctg ttccagcctc agacaggtgc 2150

 ctatcagacc ctggccaaag agtgtgtggc ccaaggctgc tgtgtagatc 2200

 tctttctctt ccctaaccag tatgtggatg tggccacact ctctgttgtg 2250

 ccccagctca ctggtggctc tgtctacaaa tatgcttcct ttcaggtgga 2300

 gaacgaccag gagcggttcc tgagtgacct gcgtcgtgat gtccagaagg 2350

 ttgttggctt tgatgctgtg atgcgggtcc ggacaagcac tggtatccgt 2400

 gctgtagatt tctttggagc tttctacatg agcaacacga cagatgtgga 2450

 gctggctggg ctagatgggg acaaaacagt gactgtggag ttcaagcatg 2500

 acgatcggct caatgaagag agcggagctc tcctgcagtg tgccctgctt 2550

 tacaccagct gtgcagggca gcgtcggctc cgcatccata atctggccct 2600

 gaactgctgc acccagctgg ctgatctata tcgaaactgt gagactgaca 2650

 cgctcatcaa ctacatggcc aagtttgcat atcggggagt cctgaatagc 2700

 cctgtgaagg ctgttcgtga cacgctcatc acccagtgtg cccagatcct 2750

 ggcctgttac agaaagaact gtgctagccc ctcctctgca ggacagttga 2800

 tccttcctga gtgcatgaag ctactcccag tttacctgaa ctgtgtgttg 2850

 aagagtgatg tcctgcagcc tggagctgaa gtcactactg atgaccgtgc 2900

 ctatgtccga cagctagtta cctccatgga tgtgactgag accaatgtct 2950

 tcttctaccc tcggctctta cctttgacaa agtctcccgt tgagagtact 3000

 accgaaccac cagcagttcg agcctctgaa gagcgtctaa gcaatgggga 3050

 tatatattta ctggagaatg ggctcaacct cttcctctgg gtgggagcaa 3100

 gcgtccaaca gggtgttgtc cagagccttt tcagcgtctc ctccttcagt 3150

 cagatcacca gtggtttgag tgttctgcca gttctggata atccactgtc 3200

 caagaaggtt cgaggcctca ttgatagctt acggggcaca gagatcccgg 3250

 tacatgaagc ttaccgtggt gaaacaggaa gacaagatgg agatgctgtt 3300

 caagcacttc ctggtggaag acaagagtct gagtggggga gcatcttatg 3350

 tggactttct ctgtcatatg cacaaggaga ttcggcagct actgagctaa 3400

 agcaagtggg taaatggcat agggcccagg ctagcttcca gaaagcaccc 3450

 caggatgtca gagaaattgg gacagtaaca tatcttatgt aagctgacct 3500

 cagtctctct ggggggaggg ggagatataa ggagacacct tctttctggg 3550

 ctcaagtatc ctgccactct gtcatgtcct gctgatggaa ggtgcccctg 3600

 ttccctcatt ctaccctctt tttcctgcta atcctgtcat aatgaatgta 3650

 gcttctcagt tcactgtata tgattcggta ttgggggttt ggaggcaccc 3700

 agaccctggc aatattatgt gtccctttgg accagtctcc caagaggaga 3750

 ggggcaggca ggaaagagtg gggatcctaa ggttactaca gggggctcag 3800

 tgtcatccac aacttcctat attagggata aaacatatag gtgcacaaga 3850

 gctggggtat agcccatagg tggtggagag aaaagtggtc agtccttctt 3900

 gggcctggag gttagcagtc aagtttctct gctttcactg ctcgctcgct 3950

 ctctcctgca atgattgatg atcactccgt ggatagagag gcacactgtc 4000

 agaggtgacc ggagaactga gttgcaaaat atattaagat ctggtagagg 4050

 taccagcttc ctttccagct ggagaggccc caacactgga tggttctgta 4100

 gggagcctag ggagcctggt catcaacttg caatacctca cagagccagt 4150

 tcacatccca ctctgagctc ccacgagaaa cactgcttct ccaggcccgg 4200

 ggttgttggg gagagaggca gaggcagctg gagcgccgtt ctctcctgct 4250

 gggacaccgc ttgggctttg gtattgactg agtggctgac agttatcttc 4300

 caaccccaac tggcttgggg gcaggacaag ggctaggctt gatggtggcc 4350

 aggcttgcct gctccccacc tgggatgccc ctgctctgga cctctcattt 4400

 ctcttcattg gtttattttt caatgcatct ttaatttgta aagaaataaa 4450

 ataaattaag atgt 4464

<210> 571
<211> 1125
<212> PRT
<213> Homo sapien

<400> 571
 Met Asn Val Asn Gln Ser Val Pro Pro Val Pro Pro Phe Gly Gln
   1               5                  10                  15

 Pro Gln Pro Ile Tyr Pro Gly Tyr His Gln Ser Ser Tyr Gly Gly
                  20                  25                  30

 Gln Ser Gly Ser Thr Ala Pro Ala Ile Pro Tyr Gly Ala Tyr Asn
                  35                  40                  45

 Gly Pro Val Pro Gly Tyr Gln Gln Thr Pro Pro Gln Gly Met Ser
                  50                  55                  60

 Arg Ala Pro Pro Ser Ser Gly Ala Pro Pro Ala Ser Thr Ala Gln
                  65                  70                  75

 Ala Pro Cys Gly Gln Ala Ala Tyr Gly Gln Phe Gly Gln Gly Asp
                  80                  85                  90

 Val Gln Asn Gly Pro Ser Ser Thr Val Gln Met Gln Arg Leu Pro
                  95                 100                 105

 Gly Ser Gln Pro Phe Gly Ser Pro Leu Ala Pro Val Gly Asn Gln
                 110                 115                 120

 Pro Pro Val Leu Gln Pro Tyr Gly Pro Pro Pro Thr Ser Ala Gln
                 125                 130                 135

 Val Ala Thr Gln Leu Ser Gly Met Gln Ile Ser Gly Ala Val Ala
                 140                 145                 150

 Pro Ala Pro Pro Ser Ser Gly Leu Gly Phe Gly Pro Pro Thr Ser
                 155                 160                 165

 Leu Ala Ser Ala Ser Gly Ser Phe Pro Asn Ser Gly Leu Tyr Gly
                 170                 175                 180

 Ser Tyr Pro Gln Gly Gln Ala Pro Pro Leu Ser Gln Ala Gln Gly
                 185                 190                 195

 His Pro Gly Ile Gln Thr Pro Gln Arg Ser Ala Pro Ser Gln Ala
                 200                 205                 210

 Ser Ser Phe Thr Pro Pro Ala Ser Gly Gly Pro Arg Leu Pro Ser
                 215                 220                 225

 Met Thr Gly Pro Leu Leu Pro Gly Gln Ser Phe Gly Gly Pro Ser
                 230                 235                 240

 Val Ser Gln Pro Asn His Val Ser Ser Pro Pro Gln Ala Leu Pro
                 245                 250                 255

 Pro Gly Thr Gln Met Thr Gly Pro Leu Gly Pro Leu Pro Pro Met
                 260                 265                 270

 His Ser Pro Gln Gln Pro Gly Tyr Gln Pro Gln Gln Asn Gly Ser
                 275                 280                 285

 Phe Gly Pro Ala Arg Gly Pro Gln Ser Asn Tyr Gly Gly Pro Tyr
                 290                 295                 300

 Pro Ala Ala Pro Thr Phe Gly Ser Gln Pro Gly Pro Pro Gln Pro
                 305                 310                 315

 Leu Pro Pro Lys Arg Leu Asp Pro Asp Ala Ile Pro Ser Pro Ile
                 320                 325                 330

 Gln Val Ile Glu Asp Asp Arg Asn Asn Arg Gly Thr Glu Pro Phe
                 335                 340                 345

 Val Thr Gly Val Arg Gly Gln Val Pro Pro Leu Val Thr Thr Asn
                 350                 355                 360

 Phe Leu Val Lys Asp Gln Gly Asn Ala Ser Pro Arg Tyr Ile Arg
                 365                 370                 375

 Cys Thr Ser Tyr Asn Ile Pro Cys Thr Ser Asp Met Ala Lys Gln
                 380                 385                 390

 Ala Gln Val Pro Leu Ala Ala Val Ile Lys Pro Leu Ala Arg Leu
                 395                 400                 405

 Pro Pro Glu Glu Ala Ser Pro Tyr Val Val Asp His Gly Glu Ser
                 410                 415                 420

 Gly Pro Leu Arg Cys Asn Arg Cys Lys Ala Tyr Met Cys Pro Phe
                 425                 430                 435

 Met Gln Phe Ile Glu Gly Gly Arg Arg Phe Gln Cys Cys Phe Cys
                 440                 445                 450

 Ser Cys Ile Asn Asp Val Pro Pro Gln Tyr Phe Gln His Leu Asp
                 455                 460                 465

 His Thr Gly Lys Arg Val Asp Ala Tyr Asp Arg Pro Glu Leu Ser
                 470                 475                 480

 Leu Gly Ser Tyr Glu Phe Leu Ala Thr Val Asp Tyr Cys Lys Asn
                 485                 490                 495

 Asn Lys Phe Pro Ser Pro Pro Ala Phe Ile Phe Met Ile Asp Val
                 500                 505                 510

 Ser Tyr Asn Ala Ile Arg Thr Gly Leu Val Arg Leu Leu Cys Glu
                 515                 520                 525

 Glu Leu Lys Ser Leu Leu Asp Phe Leu Pro Arg Glu Gly Gly Ala
                 530                 535                 540

 Glu Glu Ser Ala Ile Arg Val Gly Phe Val Thr Tyr Asn Lys Val
                 545                 550                 555

 Leu His Phe Tyr Asn Val Lys Ser Ser Leu Ala Gln Pro Gln Met
                 560                 565                 570

 Met Val Val Ser Asp Val Ala Asp Met Phe Val Pro Leu Leu Asp
                 575                 580                 585

 Gly Phe Leu Val Asn Val Asn Glu Ser Arg Ala Val Ile Thr Ser
                 590                 595                 600

 Leu Leu Asp Gln Ile Pro Glu Met Phe Ala Asp Thr Arg Glu Thr
                 605                 610                 615

 Glu Thr Val Phe Val Pro Val Ile Gln Ala Gly Met Glu Ala Leu
                 620                 625                 630

 Lys Ala Ala Glu Cys Ala Gly Lys Leu Phe Leu Phe His Thr Ser
                 635                 640                 645

 Leu Pro Ile Ala Glu Ala Pro Gly Lys Leu Lys Asn Arg Asp Asp
                 650                 655                 660

 Arg Lys Leu Ile Asn Thr Asp Lys Glu Lys Thr Leu Phe Gln Pro
                 665                 670                 675

 Gln Thr Gly Ala Tyr Gln Thr Leu Ala Lys Glu Cys Val Ala Gln
                 680                 685                 690

 Gly Cys Cys Val Asp Leu Phe Leu Phe Pro Asn Gln Tyr Val Asp
                 695                 700                 705

 Val Ala Thr Leu Ser Val Val Pro Gln Leu Thr Gly Gly Ser Val
                 710                 715                 720

 Tyr Lys Tyr Ala Ser Phe Gln Val Glu Asn Asp Gln Glu Arg Phe
                 725                 730                 735

 Leu Ser Asp Leu Arg Arg Asp Val Gln Lys Val Val Gly Phe Asp
                 740                 745                 750

 Ala Val Met Arg Val Arg Thr Ser Thr Gly Ile Arg Ala Val Asp
                 755                 760                 765

 Phe Phe Gly Ala Phe Tyr Met Ser Asn Thr Thr Asp Val Glu Leu
                 770                 775                 780

 Ala Gly Leu Asp Gly Asp Lys Thr Val Thr Val Glu Phe Lys His
                 785                 790                 795

 Asp Asp Arg Leu Asn Glu Glu Ser Gly Ala Leu Leu Gln Cys Ala
                 800                 805                 810

 Leu Leu Tyr Thr Ser Cys Ala Gly Gln Arg Arg Leu Arg Ile His
                 815                 820                 825

 Asn Leu Ala Leu Asn Cys Cys Thr Gln Leu Ala Asp Leu Tyr Arg
                 830                 835                 840

 Asn Cys Glu Thr Asp Thr Leu Ile Asn Tyr Met Ala Lys Phe Ala
                 845                 850                 855

 Tyr Arg Gly Val Leu Asn Ser Pro Val Lys Ala Val Arg Asp Thr
                 860                 865                 870

 Leu Ile Thr Gln Cys Ala Gln Ile Leu Ala Cys Tyr Arg Lys Asn
                 875                 880                 885

 Cys Ala Ser Pro Ser Ser Ala Gly Gln Leu Ile Leu Pro Glu Cys
                 890                 895                 900

 Met Lys Leu Leu Pro Val Tyr Leu Asn Cys Val Leu Lys Ser Asp
                 905                 910                 915

 Val Leu Gln Pro Gly Ala Glu Val Thr Thr Asp Asp Arg Ala Tyr
                 920                 925                 930

 Val Arg Gln Leu Val Thr Ser Met Asp Val Thr Glu Thr Asn Val
                 935                 940                 945

 Phe Phe Tyr Pro Arg Leu Leu Pro Leu Thr Lys Ser Pro Val Glu
                 950                 955                 960

 Ser Thr Thr Glu Pro Pro Ala Val Arg Ala Ser Glu Glu Arg Leu
                 965                 970                 975

 Ser Asn Gly Asp Ile Tyr Leu Leu Glu Asn Gly Leu Asn Leu Phe
                 980                 985                 990

 Leu Trp Val Gly Ala Ser Val Gln Gln Gly Val Val Gln Ser Leu
                 995                1000                1005

 Phe Ser Val Ser Ser Phe Ser Gln Ile Thr Ser Gly Leu Ser Val
                1010                1015                1020

 Leu Pro Val Leu Asp Asn Pro Leu Ser Lys Lys Val Arg Gly Leu
                1025                1030                1035

 Ile Asp Ser Leu Arg Gly Thr Glu Ile Pro Val His Glu Ala Tyr
                1040                1045                1050

 Arg Gly Glu Thr Gly Arg Gln Asp Gly Asp Ala Val Gln Ala Leu
                1055                1060                1065

 Pro Gly Gly Arg Gln Glu Ser Glu Trp Gly Ser Ile Leu Cys Gly
                1070                1075                1080

 Leu Ser Leu Ser Tyr Ala Gln Gly Asp Ser Ala Ala Thr Glu Leu
                1085                1090                1095

 Lys Gln Val Gly Lys Trp His Arg Ala Gln Ala Ser Phe Gln Lys
                1100                1105                1110

 Ala Pro Gln Asp Val Arg Glu Ile Gly Thr Val Thr Tyr Leu Met
                1115                1120                1125

<210> 572
<211> 2643
<212> DNA
<213> Homo sapien

<400> 572
 gggactacat ttcccagggg gcagaggcag gggcgggagg gggcgggccc 50

 cggcgctgct cccgcccctc ccccgtgctc gcggggagag gtaaacaaac 100

 cacgcgcggg ctgcccgcgg cacggcgggc gcggctggcg cggctggggc 150

 ggcaggggcg gcggagagcg cgccgagccg cggccgagct ggcccgcccg 200

 cccgtcgcac atgttccgga acggcgcccg gccgtagccg cctgcggcgc 250

 ctcctgtcgg cccgagaagg gagtgcggag aggcgccggt cgccacccgc 300

 ggtgcccatg gagcgggtga agatgatcaa cgtgcagcgt ctgctggagg 350

 ctgccgagtt tttggagcgc cgggagcgag agtgtgaaca tggctacgcc 400

 tcttcattcc cgtccatgcc gagcccccga ctgcagcatt caaagccccc 450

 acggaggttg agccgggcac agaaacacag cagcgggagc agcaacacca 500

 gcactgccaa cagatctaca cacaatgagc tggaaaagaa tcgacgagct 550

 catctgcgcc tttgtttaga acgcttaaaa gttctgattc cactaggacc 600

 agactgcacc cggcacacaa cacttggttt gctcaacaaa gccaaagcac 650

 acatcaagaa acttgaagaa gctgaaagaa aaagccagca ccagctcgag 700

 aatttggaac gagaacagag atttttaaag tggcgactgg aacagctgca 750

 gggtcctcag gagatggaac gaatacgaat ggacagcatt ggatcaacta 800

 tttcttcaga tcgttctgat tcagagcgag aggagattga agtggatgtt 850

 gaaagcacag agttctccca tggagaagtg gacaatataa gtaccaccag 900

 catcagtgac attgatgacc acagcagcct gccgagtatt gggagtgacg 950

 agggttactc cagtgccagt gtcaaacttt cattcacttc atagaaccca 1000

 gcatgacata acagtgcagg gcaaaatatt cactgggcca attcaataca 1050

 aacaatctct taaattgggt tcatgatgca gtctcctctt taaaacaaaa 1100

 caaaacaaaa caaaactata cttgaacaaa agggtcagag gacctgtatt 1150

 taagcaaata cttagcaaaa agtggggcag agcctcccaa ggagaacaaa 1200

 tattcagaat attcatattg gaaaaatcac aatttttaat ggcagcagaa 1250

 aacttgtgtg aaattttctt gatttgagtt gattgagaag aggacattgg 1300

 agatgccatc ctctttctct tttctagttt gctcatacta cattgagtag 1350

 acacatttaa ggatggggtt atgaaccctt cctgagcttt atggtcctaa 1400

 aagcaaaata aaaactattc gaatgaaaag acaagaaaat caggtattaa 1450

 tcttggatag ctaataatga gctattaaaa ctcagcctgg gacagtttat 1500

 catgaagcct gtggatgatc aatcctttat tattattttt tttttttgaa 1550

 aaaagctcat ttcatgctct gcaaaaggag agactcccat gaagcctttt 1600

 gaaagggatc atcatgcagc tcaactttct gttggattcc atgctaagca 1650

 agctaacctt atcctgcatt gttagcacta ggcacccagc tgccacctct 1700

 ccatcctgct gcccttaggc cacatgggag cagtccatgc atgacagcct 1750

 ctatcctaca aggcctatga gtatggattg ggggggccaa aaggaaaaag 1800

 ctccatgtgc ctctttgtct gcgtgggtca gaagagttgt gcacgcagat 1850

 tagcaggcca aggtctgagc cacagcagca tttttatttc agattttgat 1900

 aactgtttat atgtgttgaa aaccaaaatg acatcttttt aaagcttatc 1950

 cataaaaaaa aatagatgtc ttttatagtg gaaaaacaca tggggaaaaa 2000

 aatcatctat tttgatgcag catttgataa tgataaaaca cctcacacct 2050

 cactctttat agtgcacaaa atgaatgagg tctgggctag gtagaaaaag 2100

 ggtcaatgct atttttgttt ttagaatcat taccttttac cagcttttaa 2150

 ccatctgata tctatagtag acacactatc atagttaaca tagttaagtt 2200

 cagcacttgt ctcattttaa tgtaaagatt tgcttccatt ttcctacagg 2250

 cagtctctct cttcctcaca gtcccactgt gcaggtgcta ttgttactct 2300

 tacgaatatt ttcagtaatg ttattttctt ctaagtgaaa tttctagcct 2350

 gcactttgat gtcatgtgtt ccctttgtct ttcaaactcc aaggttcccc 2400

 tgtggccctc tcccttaccc tgggaaggcc tcttggagac cttacccctg 2450

 gctgtttgga ctttgtatac tttaaataat ttaactaccc ttaattactt 2500

 aaaaaaaaaa aaaagcttta tgattttcat aacttattgc tgattttaat 2550

 ggattgttaa tttcagtcct gtagttttat tttatgttta gatagggctg 2600

 ggcaaggaaa aagaaaataa agacaaccat atttagcagt gca 2643

<210> 573
<211> 228
<212> PRT
<213> Homo sapien

<400> 573
 Met Glu Arg Val Lys Met Ile Asn Val Gln Arg Leu Leu Glu Ala
   1               5                  10                  15

 Ala Glu Phe Leu Glu Arg Arg Glu Arg Glu Cys Glu His Gly Tyr
                  20                  25                  30

 Ala Ser Ser Phe Pro Ser Met Pro Ser Pro Arg Leu Gln His Ser
                  35                  40                  45

 Lys Pro Pro Arg Arg Leu Ser Arg Ala Gln Lys His Ser Ser Gly
                  50                  55                  60

 Ser Ser Asn Thr Ser Thr Ala Asn Arg Ser Thr His Asn Glu Leu
                  65                  70                  75

 Glu Lys Asn Arg Arg Ala His Leu Arg Leu Cys Leu Glu Arg Leu
                  80                  85                  90

 Lys Val Leu Ile Pro Leu Gly Pro Asp Cys Thr Arg His Thr Thr
                  95                 100                 105

 Leu Gly Leu Leu Asn Lys Ala Lys Ala His Ile Lys Lys Leu Glu
                 110                 115                 120

 Glu Ala Glu Arg Lys Ser Gln His Gln Leu Glu Asn Leu Glu Arg
                 125                 130                 135

 Glu Gln Arg Phe Leu Lys Trp Arg Leu Glu Gln Leu Gln Gly Pro
                 140                 145                 150

 Gln Glu Met Glu Arg Ile Arg Met Asp Ser Ile Gly Ser Thr Ile
                 155                 160                 165

 Ser Ser Asp Arg Ser Asp Ser Glu Arg Glu Glu Ile Glu Val Asp
                 170                 175                 180

 Val Glu Ser Thr Glu Phe Ser His Gly Glu Val Asp Asn Ile Ser
                 185                 190                 195

 Thr Thr Ser Ile Ser Asp Ile Asp Asp His Ser Ser Leu Pro Ser
                 200                 205                 210

 Ile Gly Ser Asp Glu Gly Tyr Ser Ser Ala Ser Val Lys Leu Ser
                 215                 220                 225

 Phe Thr Ser


<210> 574
<211> 3988
<212> DNA
<213> Homo sapien

<400> 574
 tgcaactccg agcgtgagtc caggctaagg ggacgccggc cggggaagag 50

 gcgcggcggg agaagcgacc gcagcgggag cccggccacc gagggctgcc 100

 ggcactaggc gcagagccgc cagcgctcgg aagcccgcgg ggtgcgggag 150

 cgggaacaga cttcttttgt agaattatcc tatggaatga tattttcata 200

 atgagtcaac aaggttacgt ggctacacct ccgtattctc agcctcagcc 250

 tggaataggc ctttctccac ctcattatgg gcactatggg gatccgtcgc 300

 acacagcatc tccaacaggt atgatgaagc cagcagggcc tttgggggcc 350

 accgccacta ggggaatgtt gcctccgggt cccccacctc ctggacccca 400

 tcagtttggt cagaatggag ctcatgccac tggtcaccct ccccaaagat 450

 ttccaggccc tccacctgtc aacaatgtgg catcctcaca tgcaccatac 500

 caaccctctg cacaatcttc ttatccaggt cctatatcca cttcatctgt 550

 cacccagctg ggcagccagc tcagtgctat gcaaatcaac agctatggtt 600

 caggcatggc tcctccaagc cagggacccc ctggccctct gtcagccaca 650

 tcattgcaga ctcctccacg acctccacag ccttccattt tgcagcctgg 700

 atctcaagtt cttccaccac cacccaccac actcaatggt cctggtgcct 750

 cacctttgcc tctaccaatg tacagaccag atgggctctc tgggcctcct 800

 cctccaaatg cccagtacca gcccccacct cttccaggcc agaccttggg 850

 tgctggatat cctccgcagc aggccaactc tggtccccag atggcaggcg 900

 cacaactgtc ttacccagga ggcttccctg gaggtcctgc acagatggct 950

 ggtccgccac agccccagaa gaagctggat cctgactcta tccctagccc 1000

 aatccaggtg attgagaatg atagagccag cagaggagga caagtttatg 1050

 ccaccaacac cagaggccag atccctcccc tggtcactac agattgcatg 1100

 atacaagacc aaggaaatgc cagtcctcga ttcatccgtt gtacaacata 1150

 ctgttttcca tgcacgtcag atatggctaa gcaagctcag attccattag 1200

 ctgctgtcat caagcccttt gccaccattc cttcaaatga gagtcccctt 1250

 tacttggtaa atcacggcga gagtggacca gtcagatgca acaggtgcaa 1300

 ggcctacatg tgcccattta tgcagttcat cgaaggagga aggagatatc 1350

 agtgtggatt ttgcaactgt gtgaatgatg ttccaccatt ctatttccaa 1400

 catctggacc acattggaag aagactggac cactatgaga aaccagagtt 1450

 atctctagga tcttatgaat atgttgccac tttggattat tgcagaaaga 1500

 gtaagcctcc caacccacca gcctttatct tcatgattga tgtttcatat 1550

 agtaacataa agaatggact tgtcaagctc atatgtgaag aactgaagac 1600

 catgctggaa aaaattccaa aggaagagca agaagagacg tctgcaattc 1650

 gagtgggttt tatcacatat aacaaagttc tccatttctt taatgtgaag 1700

 agtaatctgg cccagcctca gatgatggtg gtgactgatg ttggagaagt 1750

 ctttgttcct ttgttggatg gtttccttgt caactatcaa gaatcccaat 1800

 ctgtgattca taatttgttg gaccagattc cagacatgtt tgcagactct 1850

 aatgaaaatg agactgtctt tgcttctgtc atccaggctg gcatggaagc 1900

 actaaaggca gcagactgtc ctgggaagct gttcatcttc cattcttcct 1950

 tgccaactgc tgaagcacca gggaagctca aaaacagaga tgacaaaaaa 2000

 ctggttaata cagacaaaga gaagatactt ttccagcccc aaacaaatgt 2050

 ctatgactca ttggccaagg actgcgtggc tcacggctgc tctgtgacac 2100

 tcttcctctt tcctagtcag tatgtggacg tggcctcgct ggggctggtt 2150

 cctcagctca ctggaggaac cctttacaaa tacaacaatt tccagatgca 2200

 cttggataga caacaatttt tgaacgacct cagaaatgat attgaaaaga 2250

 aaataggctt tgatgctatt atgagggttc gtaccagcac aggtttcaga 2300

 gccactgatt tctttggtgg aatcttgatg aacaacacca ccgatgtaga 2350

 aatggctgcc atcgattgtg acaaggcagt gaccgtggag ttcaagcacg 2400

 atgacaaact cagtgaagac agtggagcct taatccagtg tgctgtgctt 2450

 tacacgacaa tcagtggtca aagaagactt cggattcaca atcttggctt 2500

 aaactgcagc tctcagctag ctgatcttta taagagctgt gagacagatg 2550

 ctcttatcaa cttctttgcc aagtcagctt ttaaagcagt tctccaccag 2600

 cctttgaagg tcatccggga aattctagtt aatcagactg cccatatgtt 2650

 ggcatgttac cggaagaatt gtgcaagtcc ttctgcagca agccagctta 2700

 ttctaccaga ttccatgaaa gtattgccag tgtacatgaa ttgcttgttg 2750

 aaaaactgtg tactactcag cagaccagag atctcaactg atgaacgagc 2800

 ataccagaga cagctggtca tgaccatggg tgtggctgac tctcagcttt 2850

 tcttctaccc acaacttctg cccatacaca cgttagatgt caagagtaca 2900

 atgttacctg ctgccgttcg ttgctctgag tcccgtcttt cagaagaagg 2950

 aatattctta ctggctaatg gtctacacat gttcctgtgg ttgggagtaa 3000

 gcagcccacc agaactgatc caaggaatat ttaatgtgcc atcttttgca 3050

 catatcaaca cagatatgac attgctgcct gaagtgggaa acccatactc 3100

 tcaacaactc agaatgataa tgggtattat ccaacaaaag aggccatatt 3150

 caatgaagct cacaattgta aagcagcgag aacaaccaga aatggttttc 3200

 cgacagttcc tggtagaaga caaaggactt tacggaggct cttcttatgt 3250

 ggatttcctt tgttgtgttc acaaggagat ctgtcagctg cttaattaat 3300

 tgaaacttct ctgtcattga tgttgcattt ccaaggagat aatctccttc 3350

 ttggtgccta attttctaga tgataatagg ctagttttga tttcttgctc 3400

 attttcagaa taactttcca ggaagagatg gcatttagaa cttcagcttt 3450

 ggtgctcagg tataaagcca attaaggtac aattgtacca taaagggaac 3500

 aatctgtttc tgattgcaca gtttctaatt tttaaaactg atgtggtttg 3550

 catttcataa aaggcaaagt ttacagaacc ataaacattc tcaattttct 3600

 ttatgctaga catataaatt atttttcaaa ctgtatagat ttggggtaaa 3650

 aagttgtctc agttcctctc ccaattgcaa tgagaaaaaa aagcttaatt 3700

 tttacattat acttaatttt ctaaaaccat gtaactccat tgaacatttt 3750

 tcaacttaag gtctgcatag cagactttta ataaccttgg gatttatctg 3800

 gtagaacaat atgtgttcta catttttttc ataattatat attgtgtatg 3850

 ttaaaactat tttccagttg ttttgtctgt aaaactgtct ttatcaatat 3900

 gcttaatggt tctttgtaca attttgaaag tttctacctg tatataatgg 3950

 atgttaacca gtatcaataa atcacttcgt ataatctt 3988

<210> 575
<211> 1032
<212> PRT
<213> Homo sapien

<400> 575
 Met Ser Gln Gln Gly Tyr Val Ala Thr Pro Pro Tyr Ser Gln Pro
   1               5                  10                  15

 Gln Pro Gly Ile Gly Leu Ser Pro Pro His Tyr Gly His Tyr Gly
                  20                  25                  30

 Asp Pro Ser His Thr Ala Ser Pro Thr Gly Met Met Lys Pro Ala
                  35                  40                  45

 Gly Pro Leu Gly Ala Thr Ala Thr Arg Gly Met Leu Pro Pro Gly
                  50                  55                  60

 Pro Pro Pro Pro Gly Pro His Gln Phe Gly Gln Asn Gly Ala His
                  65                  70                  75

 Ala Thr Gly His Pro Pro Gln Arg Phe Pro Gly Pro Pro Pro Val
                  80                  85                  90

 Asn Asn Val Ala Ser Ser His Ala Pro Tyr Gln Pro Ser Ala Gln
                  95                 100                 105

 Ser Ser Tyr Pro Gly Pro Ile Ser Thr Ser Ser Val Thr Gln Leu
                 110                 115                 120

 Gly Ser Gln Leu Ser Ala Met Gln Ile Asn Ser Tyr Gly Ser Gly
                 125                 130                 135

 Met Ala Pro Pro Ser Gln Gly Pro Pro Gly Pro Leu Ser Ala Thr
                 140                 145                 150

 Ser Leu Gln Thr Pro Pro Arg Pro Pro Gln Pro Ser Ile Leu Gln
                 155                 160                 165

 Pro Gly Ser Gln Val Leu Pro Pro Pro Pro Thr Thr Leu Asn Gly
                 170                 175                 180

 Pro Gly Ala Ser Pro Leu Pro Leu Pro Met Tyr Arg Pro Asp Gly
                 185                 190                 195

 Leu Ser Gly Pro Pro Pro Pro Asn Ala Gln Tyr Gln Pro Pro Pro
                 200                 205                 210

 Leu Pro Gly Gln Thr Leu Gly Ala Gly Tyr Pro Pro Gln Gln Ala
                 215                 220                 225

 Asn Ser Gly Pro Gln Met Ala Gly Ala Gln Leu Ser Tyr Pro Gly
                 230                 235                 240

 Gly Phe Pro Gly Gly Pro Ala Gln Met Ala Gly Pro Pro Gln Pro
                 245                 250                 255

 Gln Lys Lys Leu Asp Pro Asp Ser Ile Pro Ser Pro Ile Gln Val
                 260                 265                 270

 Ile Glu Asn Asp Arg Ala Ser Arg Gly Gly Gln Val Tyr Ala Thr
                 275                 280                 285

 Asn Thr Arg Gly Gln Ile Pro Pro Leu Val Thr Thr Asp Cys Met
                 290                 295                 300

 Ile Gln Asp Gln Gly Asn Ala Ser Pro Arg Phe Ile Arg Cys Thr
                 305                 310                 315

 Thr Tyr Cys Phe Pro Cys Thr Ser Asp Met Ala Lys Gln Ala Gln
                 320                 325                 330

 Ile Pro Leu Ala Ala Val Ile Lys Pro Phe Ala Thr Ile Pro Ser
                 335                 340                 345

 Asn Glu Ser Pro Leu Tyr Leu Val Asn His Gly Glu Ser Gly Pro
                 350                 355                 360

 Val Arg Cys Asn Arg Cys Lys Ala Tyr Met Cys Pro Phe Met Gln
                 365                 370                 375

 Phe Ile Glu Gly Gly Arg Arg Tyr Gln Cys Gly Phe Cys Asn Cys
                 380                 385                 390

 Val Asn Asp Val Pro Pro Phe Tyr Phe Gln His Leu Asp His Ile
                 395                 400                 405

 Gly Arg Arg Leu Asp His Tyr Glu Lys Pro Glu Leu Ser Leu Gly
                 410                 415                 420

 Ser Tyr Glu Tyr Val Ala Thr Leu Asp Tyr Cys Arg Lys Ser Lys
                 425                 430                 435

 Pro Pro Asn Pro Pro Ala Phe Ile Phe Met Ile Asp Val Ser Tyr
                 440                 445                 450

 Ser Asn Ile Lys Asn Gly Leu Val Lys Leu Ile Cys Glu Glu Leu
                 455                 460                 465

 Lys Thr Met Leu Glu Lys Ile Pro Lys Glu Glu Gln Glu Glu Thr
                 470                 475                 480

 Ser Ala Ile Arg Val Gly Phe Ile Thr Tyr Asn Lys Val Leu His
                 485                 490                 495

 Phe Phe Asn Val Lys Ser Asn Leu Ala Gln Pro Gln Met Met Val
                 500                 505                 510

 Val Thr Asp Val Gly Glu Val Phe Val Pro Leu Leu Asp Gly Phe
                 515                 520                 525

 Leu Val Asn Tyr Gln Glu Ser Gln Ser Val Ile His Asn Leu Leu
                 530                 535                 540

 Asp Gln Ile Pro Asp Met Phe Ala Asp Ser Asn Glu Asn Glu Thr
                 545                 550                 555

 Val Phe Ala Ser Val Ile Gln Ala Gly Met Glu Ala Leu Lys Ala
                 560                 565                 570

 Ala Asp Cys Pro Gly Lys Leu Phe Ile Phe His Ser Ser Leu Pro
                 575                 580                 585

 Thr Ala Glu Ala Pro Gly Lys Leu Lys Asn Arg Asp Asp Lys Lys
                 590                 595                 600

 Leu Val Asn Thr Asp Lys Glu Lys Ile Leu Phe Gln Pro Gln Thr
                 605                 610                 615

 Asn Val Tyr Asp Ser Leu Ala Lys Asp Cys Val Ala His Gly Cys
                 620                 625                 630

 Ser Val Thr Leu Phe Leu Phe Pro Ser Gln Tyr Val Asp Val Ala
                 635                 640                 645

 Ser Leu Gly Leu Val Pro Gln Leu Thr Gly Gly Thr Leu Tyr Lys
                 650                 655                 660

 Tyr Asn Asn Phe Gln Met His Leu Asp Arg Gln Gln Phe Leu Asn
                 665                 670                 675

 Asp Leu Arg Asn Asp Ile Glu Lys Lys Ile Gly Phe Asp Ala Ile
                 680                 685                 690

 Met Arg Val Arg Thr Ser Thr Gly Phe Arg Ala Thr Asp Phe Phe
                 695                 700                 705

 Gly Gly Ile Leu Met Asn Asn Thr Thr Asp Val Glu Met Ala Ala
                 710                 715                 720

 Ile Asp Cys Asp Lys Ala Val Thr Val Glu Phe Lys His Asp Asp
                 725                 730                 735

 Lys Leu Ser Glu Asp Ser Gly Ala Leu Ile Gln Cys Ala Val Leu
                 740                 745                 750

 Tyr Thr Thr Ile Ser Gly Gln Arg Arg Leu Arg Ile His Asn Leu
                 755                 760                 765

 Gly Leu Asn Cys Ser Ser Gln Leu Ala Asp Leu Tyr Lys Ser Cys
                 770                 775                 780

 Glu Thr Asp Ala Leu Ile Asn Phe Phe Ala Lys Ser Ala Phe Lys
                 785                 790                 795

 Ala Val Leu His Gln Pro Leu Lys Val Ile Arg Glu Ile Leu Val
                 800                 805                 810

 Asn Gln Thr Ala His Met Leu Ala Cys Tyr Arg Lys Asn Cys Ala
                 815                 820                 825

 Ser Pro Ser Ala Ala Ser Gln Leu Ile Leu Pro Asp Ser Met Lys
                 830                 835                 840

 Val Leu Pro Val Tyr Met Asn Cys Leu Leu Lys Asn Cys Val Leu
                 845                 850                 855

 Leu Ser Arg Pro Glu Ile Ser Thr Asp Glu Arg Ala Tyr Gln Arg
                 860                 865                 870

 Gln Leu Val Met Thr Met Gly Val Ala Asp Ser Gln Leu Phe Phe
                 875                 880                 885

 Tyr Pro Gln Leu Leu Pro Ile His Thr Leu Asp Val Lys Ser Thr
                 890                 895                 900

 Met Leu Pro Ala Ala Val Arg Cys Ser Glu Ser Arg Leu Ser Glu
                 905                 910                 915

 Glu Gly Ile Phe Leu Leu Ala Asn Gly Leu His Met Phe Leu Trp
                 920                 925                 930

 Leu Gly Val Ser Ser Pro Pro Glu Leu Ile Gln Gly Ile Phe Asn
                 935                 940                 945

 Val Pro Ser Phe Ala His Ile Asn Thr Asp Met Thr Leu Leu Pro
                 950                 955                 960

 Glu Val Gly Asn Pro Tyr Ser Gln Gln Leu Arg Met Ile Met Gly
                 965                 970                 975

 Ile Ile Gln Gln Lys Arg Pro Tyr Ser Met Lys Leu Thr Ile Val
                 980                 985                 990

 Lys Gln Arg Glu Gln Pro Glu Met Val Phe Arg Gln Phe Leu Val
                 995                1000                1005

 Glu Asp Lys Gly Leu Tyr Gly Gly Ser Ser Tyr Val Asp Phe Leu
                1010                1015                1020

 Cys Cys Val His Lys Glu Ile Cys Gln Leu Leu Asn
                1025                1030

<210> 576
<211> 2468
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 746-837, 978-995, 2448
<223> Unknown base

<400> 576
 gtctggagca gcaggcgccg cgtttgcgag ctaagctctc gtggcattat 50

 ccttcagtgg ggctattgga ctgacttttc ttatgctggg atgtgcctta 100

 gaggattatg gcgtttactg gcccttattc gtcctgattt tccacgccat 150

 ctcccccatc ccccatttca ttgccaaaag agtcacctat gactcagatg 200

 caaccagtag tgcctgtcgg gaactggcat atttcttcac tactggaatt 250

 gttgtttctg ccttggattt ccttacaatt caagggtttt tccttatatt 300

 tggaagagga gatgatttta gctgggagca gtggtagcac tttattctga 350

 ttacagtgca ttgaatttct tagaactcat actatctgta tacatgtgca 400

 catgcggcat tttactatga aatttaatat gctgggtttt ttaatacctt 450

 tatatatcat gttcacttta agaaagactt cataagtagg agatgagttt 500

 tattctcagc aaatagacct gtcaaattta gattatgtta ctcaaattat 550

 gttacttgtt tggctgttca tgtagtcacg gtgctctcag aaaatatatt 600

 aacgcagtct tgtaggcagc tgccacctta tgcagtgcat cgaaaccttt 650

 tgcttgggga tgtgcttgga gaggcagata acgctgaagc aggcctctca 700

 tgacccagga aggccggggt ggatccctct ttgtgttgta gtccannnnn 750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnngga cattttgatg 850

 agatccaaag gagttgtatg cacatgaaag tttgagaagc atcatcatag 900

 agaagtaaac atcacaccca acttccttat ctttccagtg gctaaaccac 950

 ttaacctctc tgggtgttac ctgctcannn nnnnnnnnnn nnnnnaagtc 1000

 tcacctgctt tcatgctgag gacaagttca gatgttcaag cctataatat 1050

 ttaggcagtt cctcaaattt atgaaaagtg ttctcagaat tgggagacag 1100

 tcaaagggta caaagcctca gttaggagga ataagtgtga ttttttttta 1150

 aagatcactt gcacagcatg ctaaatatag gaataattga atgtatattt 1200

 caatattgct aagagagtaa atttctaatg ttctcataaa aaagttaaat 1250

 atttgagatc atatgttaat tagtgtaatc attccacctt atattcaaaa 1300

 atcataaaac cgtattgtac cctataaaaa tatacaataa tttgtcaata 1350

 tataatcaaa ataaaaaaca aaacatactc tctcccccaa aaaaacatct 1400

 cagtggggaa cagatgtatc ttttcatctg aaagacaatg ctgggggaag 1450

 agctccactg agatgcgggc agggaggctg ggctcgagcc agcccctgcg 1500

 ttagcaggag ggggagaaca gataggtaac tcttttacat ttcctttatg 1550

 atctggcact tctccccagc tccttccctc tgccccccac ccctactcct 1600

 caacacttct ggtttgccct gacttctcta cggctctggc ttcttcccga 1650

 agagatatag gagccatgta agcacgcagt gggtgaactg cttaatttca 1700

 ctacatgttg atgtacttgt cttccgtcct gtaggtcttt tctatataac 1750

 tttatgccac ccttaaatga atcattgggt atacctgtca tgttggatcc 1800

 tgtaatcaca gttttccctg ctcacctttt tgtctaagat ctattgagaa 1850

 agggaaatat gggaaggaga accatttgat cagaatacaa ccaatagtct 1900

 ttaagcattg ttaaagtatg aaactgaaat acattcaaaa cacttaatcc 1950

 ttgaggcttg tgatctgagt aattagcagg tatgatgctg ggactggaaa 2000

 atagaaagta ataactaaag ggttaatgtg caacgttatt ttttggcctt 2050

 gttcatgatt ttatgttttc agtgtcctgt gtacatatag aattgttaaa 2100

 gttgtcattt ccaatattta tattagaaaa attatttaga tactttataa 2150

 ttttaaccgg catttttaat aatgacactt gcatttattg tattgtaata 2200

 aatttcactt ttaactttaa aagtttaact ttaaaatttt tttgtgatgt 2250

 tgccttgcct gaaaagataa caaaaatgag agaatttctt gatgttttaa 2300

 aatgggcagt tttgagcaat aatctgtcct aacagaacag tagcaataag 2350

 ttttaggata ccatcttgaa tgtctagttg gtgtgcaata gcttttcttt 2400

 ctaagatggc aataatgatt catttctact acattttgca aaagtgtntt 2450

 tgttgcttat acacattt 2468

<210> 577
<211> 63
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 746-837, 978-995, 2448
<223> Unknown amino acid

<400> 577
 Val Trp Ser Ser Arg Arg Arg Val Cys Glu Leu Ser Ser Arg Gly
   1               5                  10                  15

 Ile Ile Leu Gln Trp Gly Tyr Trp Thr Asp Phe Ser Tyr Ala Gly
                  20                  25                  30

 Met Cys Leu Arg Gly Leu Trp Arg Leu Leu Ala Leu Ile Arg Pro
                  35                  40                  45

 Asp Phe Pro Arg His Leu Pro His Pro Pro Phe His Cys Gln Lys
                  50                  55                  60

 Ser His Leu


<210> 578
<211> 1114
<212> DNA
<213> Homo sapien

<400> 578
 gtctggcttg ggcaggctgc ccgggccgtg gcaggaagcc ggaagcagcc 50

 gcggccccag ttcgggagac atggcgggcg ttaaagctct cgtggcatta 100

 tccttcagtg gggctattgg actgactttt cttatgctgg gatgtgcctt 150

 agaggattat ggcgtttact ggcccttatt cgtcctgatt ttccacgcca 200

 tctcccccat cccccatttc attgccaaaa gagtcaccta tgactcagat 250

 gcaaccagta gtgcctgtcg ggaactggca tatttcttca ctactggaat 300

 tgttgtttct gcctttggat ttcctgttat tcttgctcgt gtggctgtga 350

 tcaaatgggg agcctgcggc cttgtgttgg caggcaatgc agtcattttc 400

 cttacaattc aagggttttt ccttatattt ggaagaggag atgattttag 450

 ctgggagcag tggtagcact ttattctgat tacagtgcat tgaatttctt 500

 agaactcata ctatctgtat acatgtgcac atgcggcatt ttactatgaa 550

 atttaatatg ctgggttttt taataccttt atatatcatg ttcactttaa 600

 gaaagacttc ataagtagga gatgagtttt attctcagca aatagacctg 650

 tcaaatttag attatgttac tcaaattatg ttacttgttt ggctgttcat 700

 gtagtcacgg tgctctcaga aaatatatta acgcagtctt gtaggcagct 750

 gccaccttat gcagtgcatc gaaacctttt gcttggggat gtgcttggag 800

 aggcagataa cgctgaagca ggcctctcat gacccaggaa ggccggggtg 850

 gatccctctt tgtgttgtag tccatgctat taaaagtgtg gcccacagac 900

 caagagcctc aacatttcct agagccttat tagaaatgca gaatctgaag 950

 ccccactctg gacccaggac attttgatga gatccaaagg agttgtatgc 1000

 acatgaaagt ttgagaagca tcatcataga gaagtaaaca tcacacccaa 1050

 cttccttatc tttccagtgg ctaaaccact taacctctct gggtgttacc 1100

 tgctcatttg ttta 1114

<210> 579
<211> 131
<212> PRT
<213> Homo sapien

<400> 579
 Met Ala Gly Val Lys Ala Leu Val Ala Leu Ser Phe Ser Gly Ala
   1               5                  10                  15

 Ile Gly Leu Thr Phe Leu Met Leu Gly Cys Ala Leu Glu Asp Tyr
                  20                  25                  30

 Gly Val Tyr Trp Pro Leu Phe Val Leu Ile Phe His Ala Ile Ser
                  35                  40                  45

 Pro Ile Pro His Phe Ile Ala Lys Arg Val Thr Tyr Asp Ser Asp
                  50                  55                  60

 Ala Thr Ser Ser Ala Cys Arg Glu Leu Ala Tyr Phe Phe Thr Thr
                  65                  70                  75

 Gly Ile Val Val Ser Ala Phe Gly Phe Pro Val Ile Leu Ala Arg
                  80                  85                  90

 Val Ala Val Ile Lys Trp Gly Ala Cys Gly Leu Val Leu Ala Gly
                  95                 100                 105

 Asn Ala Val Ile Phe Leu Thr Ile Gln Gly Phe Phe Leu Ile Phe
                 110                 115                 120

 Gly Arg Gly Asp Asp Phe Ser Trp Glu Gln Trp
                 125                 130

<210> 580
<211> 2239
<212> DNA
<213> Homo sapien

<400> 580
 cgtccgtgac aagatgaagc tcatcatcct ggagcactat tctcaggcga 50

 gcgagtgggc ggctaaatac atcaggaacc gtatcatcca gtttaaccca 100

 gggccagaga agtacttcac cctggggctc cccactggga gtaccccact 150

 tggctgctac aagaagctga ttgaatacta taagaatggg gacctgtcct 200

 ttaaatatgt gaagaccttc aacatggatg agtacgtggg ccttcctcga 250

 gaccacccgg agagttacca ctccttcatg tggaacaact tcttcaagca 300

 cattgacatc cacccagaaa acacccacat tctggatggg aatgcagtcg 350

 acctacaggc agaatgtgat gcctttgaag agaagatcaa ggctgcaggt 400

 gggatcgagc tatttgttgg aggcatcggc cctgatggac acattgcctt 450

 caacgagcca ggctccagtc tggtgtccag gacccgtgtg aagacgctgg 500

 ccatggatac catcctggcc aatgctaggt tcttcgatgg agaactcacc 550

 aaggtgccca ccatggcctt gacggtgggg gtgggcactg tcatggatgc 600

 tagagaggtg atgatcctta tcacaggtgc tcacaaggca tttgctctgt 650

 acaaggccat cgaggaggga gtgaaccaca tgtggaccgt gtctgccttc 700

 cagcagcatc cccgcaccgt gtttgtgtgt gacgaggatg ccaccttgga 750

 gctgaaagtg aagactgtca agtatttcaa aggtttaatg cttgttcata 800

 acaagttggt ggaccccttg tacagtatca aagagaaaga aactgagaaa 850

 agccaatctt cgaagaaacc atacagcgat tagcctgtgc tgggacctag 900

 tgtcaagtac ccatagggaa aggcaggtct ttctggaaat tgtctttaga 950

 agaaagaatt gtatttcttt aatctagtat ggttactcca gataagtggg 1000

 tgaacttatt gttcttggcc atgaggctgg gagcctagtc acggagttta 1050

 gctataggga gaatgtttgt aacttaatca gaaaaaaaat atctgcaaaa 1100

 tgtactccat cattttgatg tctgccaaac ccaggttggg agttttaaac 1150

 tttttgttct gcttcagcca tggttcacac atatgacaca ctcccgtcag 1200

 gaatttctct ccttacacgc actgattttc aagtgggagg gaattagggg 1250

 cttatgtata ttggatacca cctcttgaga gtccttcttg cacaggcctg 1300

 ccccttggtt gagaaccatt gttccaagtg aaggcacaaa ctctcaatat 1350

 ctaaaataag tgcaaggaag cagtctcttt ggtcagtaac aagtgcaatg 1400

 gaaagaaaac gatcccttcc ttcttccact ttcacagctt ttctctgaac 1450

 taggagaacc tgggggtgga tttgggtggg tggggccaaa gaggaggctt 1500

 ctattgataa atccagagcc tcaaggggcc cagccacgtc aaacttctct 1550

 ccctcaggga ctctccagca ccaaaaggca gaaggtggaa gccgtttttc 1600

 ccccagagcc ctgtgttttt gtgaaaggcc tcactgtggc tcctctgttt 1650

 tacatactca ttagtaagtg ggaggtccac tggggcaaca gacactgcca 1700

 caatttcagt gttgtgttca gccaagggga cggtctggac aggcagctta 1750

 agtgtgagtt tagtcacaac tcctgagtgt cccgctctcc tgcttaccta 1800

 ggaggtgagt gccaggaaaa tacaccaaat gcttctagta ttgtttcccc 1850

 acttaaaata gtcctgctta aattcacatg gtgtggtctg atgttctgag 1900

 agcatcagga aatacaaccc ttttgcccat ttacccttct ccccggatcc 1950

 caaggtggtc tgttgctctg gcttcctttc attgtcttag gccttcatgg 2000

 agtggatgct gcctcctcct ggctgttttt gtgcctgttt gaagctactg 2050

 ctgcctccat ttctgggaaa gacctttgag agcctagccc aggcctaagg 2100

 gctatgtttg gtaccagtgt tttgtcttta gcttttctat gtgattgtgc 2150

 cgtcattctg ttttaagctc atggatcaat ggatttgttt acaatgtgat 2200

 attttctatt aaatccagta ttttcaaaaa aaaaaaaaa 2239

<210> 581
<211> 289
<212> PRT
<213> Homo sapien

<400> 581
 Met Lys Leu Ile Ile Leu Glu His Tyr Ser Gln Ala Ser Glu Trp
   1               5                  10                  15

 Ala Ala Lys Tyr Ile Arg Asn Arg Ile Ile Gln Phe Asn Pro Gly
                  20                  25                  30

 Pro Glu Lys Tyr Phe Thr Leu Gly Leu Pro Thr Gly Ser Thr Pro
                  35                  40                  45

 Leu Gly Cys Tyr Lys Lys Leu Ile Glu Tyr Tyr Lys Asn Gly Asp
                  50                  55                  60

 Leu Ser Phe Lys Tyr Val Lys Thr Phe Asn Met Asp Glu Tyr Val
                  65                  70                  75

 Gly Leu Pro Arg Asp His Pro Glu Ser Tyr His Ser Phe Met Trp
                  80                  85                  90

 Asn Asn Phe Phe Lys His Ile Asp Ile His Pro Glu Asn Thr His
                  95                 100                 105

 Ile Leu Asp Gly Asn Ala Val Asp Leu Gln Ala Glu Cys Asp Ala
                 110                 115                 120

 Phe Glu Glu Lys Ile Lys Ala Ala Gly Gly Ile Glu Leu Phe Val
                 125                 130                 135

 Gly Gly Ile Gly Pro Asp Gly His Ile Ala Phe Asn Glu Pro Gly
                 140                 145                 150

 Ser Ser Leu Val Ser Arg Thr Arg Val Lys Thr Leu Ala Met Asp
                 155                 160                 165

 Thr Ile Leu Ala Asn Ala Arg Phe Phe Asp Gly Glu Leu Thr Lys
                 170                 175                 180

 Val Pro Thr Met Ala Leu Thr Val Gly Val Gly Thr Val Met Asp
                 185                 190                 195

 Ala Arg Glu Val Met Ile Leu Ile Thr Gly Ala His Lys Ala Phe
                 200                 205                 210

 Ala Leu Tyr Lys Ala Ile Glu Glu Gly Val Asn His Met Trp Thr
                 215                 220                 225

 Val Ser Ala Phe Gln Gln His Pro Arg Thr Val Phe Val Cys Asp
                 230                 235                 240

 Glu Asp Ala Thr Leu Glu Leu Lys Val Lys Thr Val Lys Tyr Phe
                 245                 250                 255

 Lys Gly Leu Met Leu Val His Asn Lys Leu Val Asp Pro Leu Tyr
                 260                 265                 270

 Ser Ile Lys Glu Lys Glu Thr Glu Lys Ser Gln Ser Ser Lys Lys
                 275                 280                 285

 Pro Tyr Ser Asp


<210> 582
<211> 1078
<212> DNA
<213> Homo sapien

<400> 582
 gtgtcgcgcg gcgcggtggc ctcggtcggt accctgggcg cggacgagct 50

 gcctcattag tattcgtacc cacgaggcgg cgcacggggc cctcggggac 100

 agcgagcgtc gcgccatggc ttatcactcg ggctacggag cccacggctc 150

 caagcacagg gcccgggcag ccccggatcc ccctcccctc ttcgatgaca 200

 caagcggtgg ttattccagc cagcccgggg gatacccagc cacaggagca 250

 gacgtggcct tcagtgtcaa ccacttgctt ggggacccaa tggccaatgt 300

 ggctatggcc tatggcagct ccatcgcatc ccatgggaag gacatggtgc 350

 acaaggagct gcaccgtttt gtgtctgtga gcaaactcaa gtattttttt 400

 gctgtggaca cagcctacgt ggccaagaag ctagggctgc tggtcttccc 450

 ctacacacac cagaactggg aagtgcagta cagtcgtgat gctcctctgc 500

 ccccccggca agacctcaac gcccctgacc tctatatccc cacgaaggcc 550

 ttcattactt acgtgctcct ggctgggatg gcactgggca ttcagaaaag 600

 gttctccccg gaggtgctgg gcctgtgtgc aagcacagcg ctggtgtggg 650

 tggtgatgga ggtgctggcc ctgctcctgg gcctctacct ggccaccgtg 700

 cgcagtgacc tgagcacctt tcacctgctg gcctacagtg gctacaaata 750

 cgtgggaatg atcctcagtg tgctcacggg gctgctgttc ggcagcgatg 800

 gctactacgt ggcgctggcc tggacctcat cggcgctcat gtacttcatt 850

 gtgcgctctt tgcggacagc agccctgggc cccgacagca tggggggccc 900

 cgtcccccgg cagcgtctcc agctctacct gactctggga gctgcagcct 950

 tccagcccct catcatatac tggctgactt tccacctggt ccggtgaccc 1000

 cctggcccca gatggcactg agtttttcat tcattgaaga tttgatttcc 1050

 ttgaaaaaaa aaaaaaaaaa aaaaaaaa 1078

<210> 583
<211> 293
<212> PRT
<213> Homo sapien

<400> 583
 Met Ala Tyr His Ser Gly Tyr Gly Ala His Gly Ser Lys His Arg
   1               5                  10                  15

 Ala Arg Ala Ala Pro Asp Pro Pro Pro Leu Phe Asp Asp Thr Ser
                  20                  25                  30

 Gly Gly Tyr Ser Ser Gln Pro Gly Gly Tyr Pro Ala Thr Gly Ala
                  35                  40                  45

 Asp Val Ala Phe Ser Val Asn His Leu Leu Gly Asp Pro Met Ala
                  50                  55                  60

 Asn Val Ala Met Ala Tyr Gly Ser Ser Ile Ala Ser His Gly Lys
                  65                  70                  75

 Asp Met Val His Lys Glu Leu His Arg Phe Val Ser Val Ser Lys
                  80                  85                  90

 Leu Lys Tyr Phe Phe Ala Val Asp Thr Ala Tyr Val Ala Lys Lys
                  95                 100                 105

 Leu Gly Leu Leu Val Phe Pro Tyr Thr His Gln Asn Trp Glu Val
                 110                 115                 120

 Gln Tyr Ser Arg Asp Ala Pro Leu Pro Pro Arg Gln Asp Leu Asn
                 125                 130                 135

 Ala Pro Asp Leu Tyr Ile Pro Thr Lys Ala Phe Ile Thr Tyr Val
                 140                 145                 150

 Leu Leu Ala Gly Met Ala Leu Gly Ile Gln Lys Arg Phe Ser Pro
                 155                 160                 165

 Glu Val Leu Gly Leu Cys Ala Ser Thr Ala Leu Val Trp Val Val
                 170                 175                 180

 Met Glu Val Leu Ala Leu Leu Leu Gly Leu Tyr Leu Ala Thr Val
                 185                 190                 195

 Arg Ser Asp Leu Ser Thr Phe His Leu Leu Ala Tyr Ser Gly Tyr
                 200                 205                 210

 Lys Tyr Val Gly Met Ile Leu Ser Val Leu Thr Gly Leu Leu Phe
                 215                 220                 225

 Gly Ser Asp Gly Tyr Tyr Val Ala Leu Ala Trp Thr Ser Ser Ala
                 230                 235                 240

 Leu Met Tyr Phe Ile Val Arg Ser Leu Arg Thr Ala Ala Leu Gly
                 245                 250                 255

 Pro Asp Ser Met Gly Gly Pro Val Pro Arg Gln Arg Leu Gln Leu
                 260                 265                 270

 Tyr Leu Thr Leu Gly Ala Ala Ala Phe Gln Pro Leu Ile Ile Tyr
                 275                 280                 285

 Trp Leu Thr Phe His Leu Val Arg
                 290

<210> 584
<211> 7869
<212> DNA
<213> Homo sapien

<400> 584
 ggcacgaggt ttggggcatc tccgcggtcc ggcccggggc cccgggatct 50

 cggctgtcct tcctcccggc ataagatgca catttttctg ctctggagcc 100

 gggaatgaaa tattcttgag ttcttacaac tttatgacga gacccatgtg 150

 tggtgctatt gagaaattca ttgggaagtt ggaagacatt tcaaacaaca 200

 ggttgttttg gtttctatag tacaattggg gtggcattct gttttgtgaa 250

 aggaggaagg acttaggcca gaaaactcat atgctatggt taactggttc 300

 ccagcctccg agaatcttgt tttccatggt gtaaaactta ctcagcatca 350

 ggataaggga taacgactct atggatatac agaatccttc accatggtaa 400

 aactcgcaaa cccgctttat actgagtgga ttttggaggc catcaaaaaa 450

 gtgaaaaagc agaaacagcg tccttcagaa gaaaggatat gcaatgctgt 500

 gtcttcatcc catggcttgg atcgtaaaac tgttttagaa caattggagt 550

 tgagtgttaa agatggaaca attttaaaag tctcaaataa aggactcaat 600

 tcctataaag atcctgataa tcctgggcga atagcacttc ctaagcctcg 650

 gaaccatgga aaattggata ataaacaaaa tgtggattgg aataaactga 700

 taaagcgggc agttgagggc ttggcagagt ctggtggctc aactttgaaa 750

 agcattgaac gttttttgaa aggtcagaag gatgtgtctg cattattcgg 800

 aggcagtgct gcctctggct ttcaccagca gttacgattg gctatcaaac 850

 gtgccattgg ccacggcaga ctccttaaag atggacctct ttatcggctc 900

 aacactaaag caaccaacgt ggatgggaaa gagagttgtg agtctctttc 950

 ctgtttacct ccagtgtccc ttcttccaca tgaaaaggat aagccggttg 1000

 ctgaaccaat ccccatctgt agtttctgtc ttggtacaaa agaacaaaac 1050

 cgagaaaaga agccagagga actcatctcc tgtgccgact gtggcaacag 1100

 tggccatcca tcctgtttaa agttttcccc tgaactaacg gttcgagtga 1150

 aggccttacg gtggcagtgc atcgagtgta aaacatgcag ctcctgtcga 1200

 gatcaaggca aaaatgcgga taacatgctc ttttgtgatt catgtgaccg 1250

 aggttttcac atggagtgtt gtgatccgcc actcacccgt atgccaaaag 1300

 gcatgtggat atgtcaaata tgtcgaccta ggaaaaaagg acgaaaactt 1350

 ctacaaaaga aggcagcaca gataaaacgg cgctatacta atccaatagg 1400

 acgtccaaaa aacaggttaa agaaacaaaa cacggtatca aaaggtccct 1450

 tcagcaaagt tcgaactggc cctggaaggg gtaggaaacg aaaaatcact 1500

 ctttccagcc aatcagcatc atcatcatca gaagaaggat atttagagcg 1550

 gatagatggc ttggacttct gcagagatag caatgtctcc ttgaggttca 1600

 acaagaaaac caaagggctc attgatggcc ttaccaaatt ttttacccct 1650

 tcccctgatg ggcggaaagc tcggggggaa gtggtggact actctgagca 1700

 atatcgaatc agaaagaggg gcaacaggaa atcaagcact tcagattggc 1750

 ccacagacaa tcaggatggc tgggatggca aacaagaaaa tgaggagcga 1800

 ctttttggga gccaggaaat catgactgag aaagatatgg aattatttcg 1850

 tgatatccaa gaacaagcac tgcagaaagt tggagtgact ggtccccctg 1900

 atccacaagt ccgctgtccc tctgtcattg agtttgggaa gtatgaaatt 1950

 cacacctggt actcctcccc atatcctcaa gaatactcaa ggctgcccaa 2000

 attgtatctt tgtgaatttt gtctaaaata tatgaaaagt agaactattc 2050

 tgcagcagca catgaagaaa tgtggttggt tccatcctcc tgccaatgag 2100

 atttacagaa agaataatat ttctgtcttt gaggttgatg ggaatgtgag 2150

 taccatttat tgtcaaaacc tgtgtctttt ggcaaagttg tttcttgacc 2200

 acaaaaccct ctattacgat gtggagccat ttctttttta tgtactaaca 2250

 cagaatgatg tcaagggctg ccaccttgtt ggctactttt ctaaggaaaa 2300

 gcactgccaa cagaagtaca atgtttcctg tataatgatt cttcctcaat 2350

 accagcgtaa gggctatggc aggtttctca tcgatttcag ttatttgtta 2400

 tcaaagcgtg aaggccaagc agggtctcca gagaaaccgt tatctgatct 2450

 gggtcgtctt tcctacatgg catattggaa aagtgtaata ttggagtgcc 2500

 tttatcacca aaatgacaag cagatcagca ttaagaagtt aagcaagttg 2550

 actggaatct gccctcaaga catcacttcc acactccacc acctacgaat 2600

 gctggacttc cgtagtgacc aatttgtgat tatccgccgg gaaaaactta 2650

 tccaggatca catggcaaag cttcagctga atttgcgacc tgtagatgta 2700

 gatccagaat gtttgcgctg gactccagtc atagtgtcca actctgtggt 2750

 ctcagaggag gaagaagagg aggctgagga aggagaaaac gaagagccac 2800

 agtgccagga aagagaatta gagatcagtg tgggaaagtc tgtgtctcat 2850

 gagaacaaag aacaagattc ttattcagta gaaagtgaaa agaaaccaga 2900

 agttatggct ccagtcagtt ctacacgttt gagcaaacaa gtccttcctc 2950

 atgatagtct tcctgcaaat agccagccat ctcggagggg ccgctggggg 3000

 aggaagaaca gaaaaaccca ggaacgtttt ggtgataaag attctaaact 3050

 gctcttggaa gagacgtctt cagctcctca ggaacaatat ggagaatgtg 3100

 gggagaaatc agaagccacc caggaacaat acactgaaag tgaagaacag 3150

 ctggtggctt ctgaggagca gccaagccag gacgggaaac ctgaccttcc 3200

 caagagaaga ctcagtgagg gggttgagcc ctggcgagga cagctcaaga 3250

 aaagccctga ggctctgaag tgcagattaa cagaaggaag tgagaggctg 3300

 ccccgtcgct acagtgaggg tgacagggct gtcctcaggg gcttcagtga 3350

 gagcagcgag gaggaggagg agccggaaag ccctcggtca agctcgccac 3400

 caattctcac aaagcccacg ctgaagcgaa agaaaccatt tctccaccga 3450

 aggaggagag tccgaaagcg caaacaccac aatagcagtg tagtcacaga 3500

 aactatttct gagaccactg aagtgttaga tgaacctttt gaagattctg 3550

 actccgagag gccaatgcca agattagaac ccacatttga gatcgatgaa 3600

 gaagaggagg aagaggatga aaatgaactt ttccctagag aatacttccg 3650

 tcgtttgtct tcgcaggatg tactcaggtg tcagtcctct tctaagagga 3700

 agtctaaaga tgaagaagaa gatgaagagt cagatgatgc tgatgacact 3750

 cctatcttaa agccagtatc tcttttgcga aaacgtgatg tgaagaattc 3800

 tcctcttgag ccagatacat ccacaccttt gaaaaagaaa aagggatggc 3850

 ccaaaggcaa gagccgcaaa ccaatccact ggaagaaaag acctggtcga 3900

 aaaccaggat ttaagttgag tcgggaaatc atgccagttt ctactcaagc 3950

 atgcgtcatt gagcccatcg tttccattcc taaagctgga cgtaaaccca 4000

 agatccagga gagtgaagaa actgttgagc caaaagaaga catgccccta 4050

 cccgaggaga ggaaggagga ggaggagatg caagcagagg cagaagaggc 4100

 tgaagagggt gaggaagagg atgcagccag cagtgaagtc ccagcagcct 4150

 ctccagcaga cagcagcaat agtcctgaga ccgaaaccaa ggagcctgag 4200

 gtggaggagg aagaagagaa gccccgtgtc tcagaggagc agaggcagtc 4250

 agaggaggag cagcaggaat tagaggagcc agagccagag gaggaggaag 4300

 atgcagctgc agagactgcc cagaatgacg accacgacgc tgatgatgag 4350

 gatgatggcc acctggagtc cacaaagaaa aaggagctag aggaacagcc 4400

 cacgagggaa gatgtcaagg aggagcctgg tgttcaagag tcttttttag 4450

 atgctaatat gcagaagagt agggaaaaga taaaggataa agaggaaacc 4500

 gagctggatt ccgaagagga gcagccttcc catgacacgt ccgtggtgtc 4550

 agagcagatg gctgggtctg aggacgacca cgaagaagac tcccacacta 4600

 aggaagagtt aatcgaatta aaagaggagg aagagattcc tcatagtgag 4650

 ctggatctgg aaactgtaca ggcagtgcag tctttgactc aagaagaaag 4700

 cagtgagcat gagggcgcct accaggactg tgaggaaact cttgcggcgt 4750

 gtcagaccct gcagagttac acccaggctg acgaggaccc tcagatgtcc 4800

 atggttgaag actgtcatgc gtcagaacat aatagcccta tctcctccgt 4850

 tcagtctcac cccagccagt cagtccgttc ggtcagcagt cccaacgtgc 4900

 ctgcccttga gagtggctac acccagatca gcccagaaca aggatccctg 4950

 tccgcaccct ctatgcagaa catggagacc agccccatga tggatgtgcc 5000

 ttccgtatca gaccactctc agcaggtggt ggacagcggc ttcagtgacc 5050

 tgggcagcat tgagagcacc actgaaaact atgagaaccc aagcagttac 5100

 gactccacga tgggcggcag catctgtggg aacagctctt cccagagcag 5150

 ctgctcctac ggtgggctgt cgtcctccag cagcctcacc cagagcagct 5200

 gtgtggtcac tcagcagatg gccagcatgg gcagcagctg cagcatgatg 5250

 cagcagagca gcgtccagcc tgctgccaac tgcagcatca agtcacctca 5300

 gagctgcgtg gtggagaggc ctcccagtaa ccagcagcag cagccgccac 5350

 caccgcctcc acagcagcca cagccgccgc cgccacaacc acaaccagca 5400

 ccacagcctc caccacccca gcagcagccg caacagcagc cgcagcctca 5450

 gccccagcag cctccacccc caccccctcc ccagcagcag cccccgctgt 5500

 cacagtgtag tatgaataac agtttcaccc cagctcctat gatcatggag 5550

 ataccagaat ctggaagcac tgggaacata agtatctatg agaggattcc 5600

 aggggatttt ggtgccggca gctactctca accatcagcc accttcagcc 5650

 tagccaagct gcagcagctg accaacacca ttatggaccc tcatgccatg 5700

 ccttatagcc attctcctgc tgtgacttcc tatgcaacca gtgtttctct 5750

 gtccaataca ggactggctc agctggctcc atctcatccc ttagctggga 5800

 ctcctcaagc acaagccacc atgacgccac ccccaaactt ggcatccact 5850

 accatgaacc tcacatctcc tctgcttcag tgcaacatgt ctgccaccaa 5900

 cattggcatt cctcacacgc agagattgca agggcaaatg ccagtgaagg 5950

 ggcacatttc catccgctcc aagtctgcgc cactgccctc tgcggctgct 6000

 caccagcagc agctgtatgg ccgtagccca tcggcagttg ccatgcaggc 6050

 tggccctcgc gcactggctg ttcagcgtgg catgaacatg ggggttaatc 6100

 tgatgcctac tcccgcctat aatgtcaatt ccatgaatat gaacaccttg 6150

 aatgccatga acagctatcg aatgacacag cccatgatga acagcagtta 6200

 ccatagtaac cctgcctaca tgaaccagac agcacagtat cctatgcaga 6250

 tgcagatggg aatgatgggg agccaggcct atacccagca gcctatgcag 6300

 cctaaccctc atgggaacat gatgtacaca ggcccctccc atcacagcta 6350

 catgaacgct gctggcgtgc ccaagcagtc actcaacgga ccttacatga 6400

 gaagatgagc aagatgaact tgcaatcaaa aacttaaata tatataaata 6450

 aaggaacctt ttatactgac aaaccagaga aaaatggacc tttttccagt 6500

 taaaatattg ctgtagattt agaggaattt ttctttggtt tattttattt 6550

 tttagaaaac ctgatcttct cttttttttg ggttcatttt gttgtgggtt 6600

 ttggttttct tcacaatctt gaacatttta cagtagaact catctaaaaa 6650

 tggatttggg gatggggaaa catgcacaaa atcttttcat aattaaaaag 6700

 agccttactt tctttacata ccacatggac agaatttgtg taaaagtgaa 6750

 ttatctttat tttaaaatgt atgtttcccc tcactgtttg cagctcccaa 6800

 tgttgtcatt tttaaatgtt atatacatct caagggttaa ccagaccctt 6850

 tcctccaaac ccaacctttc atttcctact tcattccagc aggaggcact 6900

 taggggagac tcggatgggg acatggagaa caacccaagc tccttaaact 6950

 tattattatt gttaatatta ttattattat tattaataaa gtgaggcagg 7000

 aaaatgcttc tccttttaaa atcccctcca ctcctcacac acacacacct 7050

 cttgaaaccc ttccccaaga atgtttcttt atagacggac ttcattgaaa 7100

 tctttgttgt tcttgaatca agtgtaatat aatttttttc ttctttttta 7150

 aaatattccc actcagcact cagagacaca aaaatactgt aagtctcaat 7200

 taacagcaga atctcagaga aaagctgttt gcaatccaaa tccagccttt 7250

 ggaggaatag agatggtcaa ttaacaatca aaaagaggag attaacctct 7300

 tgttttttta ccacctggtg aatcagccat aacgcacaca cacgccaccc 7350

 agcctcttgt ttctagtatg tactttgaaa tgctaactga gggtcttgat 7400

 gcttgagcct ttgactgata aaactcaaat agcagtcccc agtgatttgc 7450

 ctcttaggtt ctttcttaaa ttgttggtgg atgactgtac attttagtga 7500

 tttgaaaaat aactgacaaa ccattgaaac agtttatttt atgttggaag 7550

 agatggcgca gatgtgtgtc agaagggaga tcacggtgtg agtttcgtag 7600

 ctatttaagt gatacatacc tctagttttt gtatgtcttt tgagatcctg 7650

 agttcatccc ctgtgaatca gagtgcacaa gcacctctcc tgtgagtggc 7700

 taatgagaag agggacagac cgaccaccag cacagtaggg cagatctgga 7750

 cagcagaatg ttataacgca agttcatgtg ttgctcccaa ctccattctc 7800

 ttttctctcg tgcaaccagt ttgcccattc tcttcctatt acttgctcca 7850

 gggataggta aaaaaaaaa 7869

<210> 585
<211> 2000
<212> PRT
<213> Homo sapien

<400> 585
 Met Val Lys Leu Ala Asn Pro Leu Tyr Thr Glu Trp Ile Leu Glu
   1               5                  10                  15

 Ala Ile Lys Lys Val Lys Lys Gln Lys Gln Arg Pro Ser Glu Glu
                  20                  25                  30

 Arg Ile Cys Asn Ala Val Ser Ser Ser His Gly Leu Asp Arg Lys
                  35                  40                  45

 Thr Val Leu Glu Gln Leu Glu Leu Ser Val Lys Asp Gly Thr Ile
                  50                  55                  60

 Leu Lys Val Ser Asn Lys Gly Leu Asn Ser Tyr Lys Asp Pro Asp
                  65                  70                  75

 Asn Pro Gly Arg Ile Ala Leu Pro Lys Pro Arg Asn His Gly Lys
                  80                  85                  90

 Leu Asp Asn Lys Gln Asn Val Asp Trp Asn Lys Leu Ile Lys Arg
                  95                 100                 105

 Ala Val Glu Gly Leu Ala Glu Ser Gly Gly Ser Thr Leu Lys Ser
                 110                 115                 120

 Ile Glu Arg Phe Leu Lys Gly Gln Lys Asp Val Ser Ala Leu Phe
                 125                 130                 135

 Gly Gly Ser Ala Ala Ser Gly Phe His Gln Gln Leu Arg Leu Ala
                 140                 145                 150

 Ile Lys Arg Ala Ile Gly His Gly Arg Leu Leu Lys Asp Gly Pro
                 155                 160                 165

 Leu Tyr Arg Leu Asn Thr Lys Ala Thr Asn Val Asp Gly Lys Glu
                 170                 175                 180

 Ser Cys Glu Ser Leu Ser Cys Leu Pro Pro Val Ser Leu Leu Pro
                 185                 190                 195

 His Glu Lys Asp Lys Pro Val Ala Glu Pro Ile Pro Ile Cys Ser
                 200                 205                 210

 Phe Cys Leu Gly Thr Lys Glu Gln Asn Arg Glu Lys Lys Pro Glu
                 215                 220                 225

 Glu Leu Ile Ser Cys Ala Asp Cys Gly Asn Ser Gly His Pro Ser
                 230                 235                 240

 Cys Leu Lys Phe Ser Pro Glu Leu Thr Val Arg Val Lys Ala Leu
                 245                 250                 255

 Arg Trp Gln Cys Ile Glu Cys Lys Thr Cys Ser Ser Cys Arg Asp
                 260                 265                 270

 Gln Gly Lys Asn Ala Asp Asn Met Leu Phe Cys Asp Ser Cys Asp
                 275                 280                 285

 Arg Gly Phe His Met Glu Cys Cys Asp Pro Pro Leu Thr Arg Met
                 290                 295                 300

 Pro Lys Gly Met Trp Ile Cys Gln Ile Cys Arg Pro Arg Lys Lys
                 305                 310                 315

 Gly Arg Lys Leu Leu Gln Lys Lys Ala Ala Gln Ile Lys Arg Arg
                 320                 325                 330

 Tyr Thr Asn Pro Ile Gly Arg Pro Lys Asn Arg Leu Lys Lys Gln
                 335                 340                 345

 Asn Thr Val Ser Lys Gly Pro Phe Ser Lys Val Arg Thr Gly Pro
                 350                 355                 360

 Gly Arg Gly Arg Lys Arg Lys Ile Thr Leu Ser Ser Gln Ser Ala
                 365                 370                 375

 Ser Ser Ser Ser Glu Glu Gly Tyr Leu Glu Arg Ile Asp Gly Leu
                 380                 385                 390

 Asp Phe Cys Arg Asp Ser Asn Val Ser Leu Arg Phe Asn Lys Lys
                 395                 400                 405

 Thr Lys Gly Leu Ile Asp Gly Leu Thr Lys Phe Phe Thr Pro Ser
                 410                 415                 420

 Pro Asp Gly Arg Lys Ala Arg Gly Glu Val Val Asp Tyr Ser Glu
                 425                 430                 435

 Gln Tyr Arg Ile Arg Lys Arg Gly Asn Arg Lys Ser Ser Thr Ser
                 440                 445                 450

 Asp Trp Pro Thr Asp Asn Gln Asp Gly Trp Asp Gly Lys Gln Glu
                 455                 460                 465

 Asn Glu Glu Arg Leu Phe Gly Ser Gln Glu Ile Met Thr Glu Lys
                 470                 475                 480

 Asp Met Glu Leu Phe Arg Asp Ile Gln Glu Gln Ala Leu Gln Lys
                 485                 490                 495

 Val Gly Val Thr Gly Pro Pro Asp Pro Gln Val Arg Cys Pro Ser
                 500                 505                 510

 Val Ile Glu Phe Gly Lys Tyr Glu Ile His Thr Trp Tyr Ser Ser
                 515                 520                 525

 Pro Tyr Pro Gln Glu Tyr Ser Arg Leu Pro Lys Leu Tyr Leu Cys
                 530                 535                 540

 Glu Phe Cys Leu Lys Tyr Met Lys Ser Arg Thr Ile Leu Gln Gln
                 545                 550                 555

 His Met Lys Lys Cys Gly Trp Phe His Pro Pro Ala Asn Glu Ile
                 560                 565                 570

 Tyr Arg Lys Asn Asn Ile Ser Val Phe Glu Val Asp Gly Asn Val
                 575                 580                 585

 Ser Thr Ile Tyr Cys Gln Asn Leu Cys Leu Leu Ala Lys Leu Phe
                 590                 595                 600

 Leu Asp His Lys Thr Leu Tyr Tyr Asp Val Glu Pro Phe Leu Phe
                 605                 610                 615

 Tyr Val Leu Thr Gln Asn Asp Val Lys Gly Cys His Leu Val Gly
                 620                 625                 630

 Tyr Phe Ser Lys Glu Lys His Cys Gln Gln Lys Tyr Asn Val Ser
                 635                 640                 645

 Cys Ile Met Ile Leu Pro Gln Tyr Gln Arg Lys Gly Tyr Gly Arg
                 650                 655                 660

 Phe Leu Ile Asp Phe Ser Tyr Leu Leu Ser Lys Arg Glu Gly Gln
                 665                 670                 675

 Ala Gly Ser Pro Glu Lys Pro Leu Ser Asp Leu Gly Arg Leu Ser
                 680                 685                 690

 Tyr Met Ala Tyr Trp Lys Ser Val Ile Leu Glu Cys Leu Tyr His
                 695                 700                 705

 Gln Asn Asp Lys Gln Ile Ser Ile Lys Lys Leu Ser Lys Leu Thr
                 710                 715                 720

 Gly Ile Cys Pro Gln Asp Ile Thr Ser Thr Leu His His Leu Arg
                 725                 730                 735

 Met Leu Asp Phe Arg Ser Asp Gln Phe Val Ile Ile Arg Arg Glu
                 740                 745                 750

 Lys Leu Ile Gln Asp His Met Ala Lys Leu Gln Leu Asn Leu Arg
                 755                 760                 765

 Pro Val Asp Val Asp Pro Glu Cys Leu Arg Trp Thr Pro Val Ile
                 770                 775                 780

 Val Ser Asn Ser Val Val Ser Glu Glu Glu Glu Glu Glu Ala Glu
                 785                 790                 795

 Glu Gly Glu Asn Glu Glu Pro Gln Cys Gln Glu Arg Glu Leu Glu
                 800                 805                 810

 Ile Ser Val Gly Lys Ser Val Ser His Glu Asn Lys Glu Gln Asp
                 815                 820                 825

 Ser Tyr Ser Val Glu Ser Glu Lys Lys Pro Glu Val Met Ala Pro
                 830                 835                 840

 Val Ser Ser Thr Arg Leu Ser Lys Gln Val Leu Pro His Asp Ser
                 845                 850                 855

 Leu Pro Ala Asn Ser Gln Pro Ser Arg Arg Gly Arg Trp Gly Arg
                 860                 865                 870

 Lys Asn Arg Lys Thr Gln Glu Arg Phe Gly Asp Lys Asp Ser Lys
                 875                 880                 885

 Leu Leu Leu Glu Glu Thr Ser Ser Ala Pro Gln Glu Gln Tyr Gly
                 890                 895                 900

 Glu Cys Gly Glu Lys Ser Glu Ala Thr Gln Glu Gln Tyr Thr Glu
                 905                 910                 915

 Ser Glu Glu Gln Leu Val Ala Ser Glu Glu Gln Pro Ser Gln Asp
                 920                 925                 930

 Gly Lys Pro Asp Leu Pro Lys Arg Arg Leu Ser Glu Gly Val Glu
                 935                 940                 945

 Pro Trp Arg Gly Gln Leu Lys Lys Ser Pro Glu Ala Leu Lys Cys
                 950                 955                 960

 Arg Leu Thr Glu Gly Ser Glu Arg Leu Pro Arg Arg Tyr Ser Glu
                 965                 970                 975

 Gly Asp Arg Ala Val Leu Arg Gly Phe Ser Glu Ser Ser Glu Glu
                 980                 985                 990

 Glu Glu Glu Pro Glu Ser Pro Arg Ser Ser Ser Pro Pro Ile Leu
                 995                1000                1005

 Thr Lys Pro Thr Leu Lys Arg Lys Lys Pro Phe Leu His Arg Arg
                1010                1015                1020

 Arg Arg Val Arg Lys Arg Lys His His Asn Ser Ser Val Val Thr
                1025                1030                1035

 Glu Thr Ile Ser Glu Thr Thr Glu Val Leu Asp Glu Pro Phe Glu
                1040                1045                1050

 Asp Ser Asp Ser Glu Arg Pro Met Pro Arg Leu Glu Pro Thr Phe
                1055                1060                1065

 Glu Ile Asp Glu Glu Glu Glu Glu Glu Asp Glu Asn Glu Leu Phe
                1070                1075                1080

 Pro Arg Glu Tyr Phe Arg Arg Leu Ser Ser Gln Asp Val Leu Arg
                1085                1090                1095

 Cys Gln Ser Ser Ser Lys Arg Lys Ser Lys Asp Glu Glu Glu Asp
                1100                1105                1110

 Glu Glu Ser Asp Asp Ala Asp Asp Thr Pro Ile Leu Lys Pro Val
                1115                1120                1125

 Ser Leu Leu Arg Lys Arg Asp Val Lys Asn Ser Pro Leu Glu Pro
                1130                1135                1140

 Asp Thr Ser Thr Pro Leu Lys Lys Lys Lys Gly Trp Pro Lys Gly
                1145                1150                1155

 Lys Ser Arg Lys Pro Ile His Trp Lys Lys Arg Pro Gly Arg Lys
                1160                1165                1170

 Pro Gly Phe Lys Leu Ser Arg Glu Ile Met Pro Val Ser Thr Gln
                1175                1180                1185

 Ala Cys Val Ile Glu Pro Ile Val Ser Ile Pro Lys Ala Gly Arg
                1190                1195                1200

 Lys Pro Lys Ile Gln Glu Ser Glu Glu Thr Val Glu Pro Lys Glu
                1205                1210                1215

 Asp Met Pro Leu Pro Glu Glu Arg Lys Glu Glu Glu Glu Met Gln
                1220                1225                1230

 Ala Glu Ala Glu Glu Ala Glu Glu Gly Glu Glu Glu Asp Ala Ala
                1235                1240                1245

 Ser Ser Glu Val Pro Ala Ala Ser Pro Ala Asp Ser Ser Asn Ser
                1250                1255                1260

 Pro Glu Thr Glu Thr Lys Glu Pro Glu Val Glu Glu Glu Glu Glu
                1265                1270                1275

 Lys Pro Arg Val Ser Glu Glu Gln Arg Gln Ser Glu Glu Glu Gln
                1280                1285                1290

 Gln Glu Leu Glu Glu Pro Glu Pro Glu Glu Glu Glu Asp Ala Ala
                1295                1300                1305

 Ala Glu Thr Ala Gln Asn Asp Asp His Asp Ala Asp Asp Glu Asp
                1310                1315                1320

 Asp Gly His Leu Glu Ser Thr Lys Lys Lys Glu Leu Glu Glu Gln
                1325                1330                1335

 Pro Thr Arg Glu Asp Val Lys Glu Glu Pro Gly Val Gln Glu Ser
                1340                1345                1350

 Phe Leu Asp Ala Asn Met Gln Lys Ser Arg Glu Lys Ile Lys Asp
                1355                1360                1365

 Lys Glu Glu Thr Glu Leu Asp Ser Glu Glu Glu Gln Pro Ser His
                1370                1375                1380

 Asp Thr Ser Val Val Ser Glu Gln Met Ala Gly Ser Glu Asp Asp
                1385                1390                1395

 His Glu Glu Asp Ser His Thr Lys Glu Glu Leu Ile Glu Leu Lys
                1400                1405                1410

 Glu Glu Glu Glu Ile Pro His Ser Glu Leu Asp Leu Glu Thr Val
                1415                1420                1425

 Gln Ala Val Gln Ser Leu Thr Gln Glu Glu Ser Ser Glu His Glu
                1430                1435                1440

 Gly Ala Tyr Gln Asp Cys Glu Glu Thr Leu Ala Ala Cys Gln Thr
                1445                1450                1455

 Leu Gln Ser Tyr Thr Gln Ala Asp Glu Asp Pro Gln Met Ser Met
                1460                1465                1470

 Val Glu Asp Cys His Ala Ser Glu His Asn Ser Pro Ile Ser Ser
                1475                1480                1485

 Val Gln Ser His Pro Ser Gln Ser Val Arg Ser Val Ser Ser Pro
                1490                1495                1500

 Asn Val Pro Ala Leu Glu Ser Gly Tyr Thr Gln Ile Ser Pro Glu
                1505                1510                1515

 Gln Gly Ser Leu Ser Ala Pro Ser Met Gln Asn Met Glu Thr Ser
                1520                1525                1530

 Pro Met Met Asp Val Pro Ser Val Ser Asp His Ser Gln Gln Val
                1535                1540                1545

 Val Asp Ser Gly Phe Ser Asp Leu Gly Ser Ile Glu Ser Thr Thr
                1550                1555                1560

 Glu Asn Tyr Glu Asn Pro Ser Ser Tyr Asp Ser Thr Met Gly Gly
                1565                1570                1575

 Ser Ile Cys Gly Asn Ser Ser Ser Gln Ser Ser Cys Ser Tyr Gly
                1580                1585                1590

 Gly Leu Ser Ser Ser Ser Ser Leu Thr Gln Ser Ser Cys Val Val
                1595                1600                1605

 Thr Gln Gln Met Ala Ser Met Gly Ser Ser Cys Ser Met Met Gln
                1610                1615                1620

 Gln Ser Ser Val Gln Pro Ala Ala Asn Cys Ser Ile Lys Ser Pro
                1625                1630                1635

 Gln Ser Cys Val Val Glu Arg Pro Pro Ser Asn Gln Gln Gln Gln
                1640                1645                1650

 Pro Pro Pro Pro Pro Pro Gln Gln Pro Gln Pro Pro Pro Pro Gln
                1655                1660                1665

 Pro Gln Pro Ala Pro Gln Pro Pro Pro Pro Gln Gln Gln Pro Gln
                1670                1675                1680

 Gln Gln Pro Gln Pro Gln Pro Gln Gln Pro Pro Pro Pro Pro Pro
                1685                1690                1695

 Pro Gln Gln Gln Pro Pro Leu Ser Gln Cys Ser Met Asn Asn Ser
                1700                1705                1710

 Phe Thr Pro Ala Pro Met Ile Met Glu Ile Pro Glu Ser Gly Ser
                1715                1720                1725

 Thr Gly Asn Ile Ser Ile Tyr Glu Arg Ile Pro Gly Asp Phe Gly
                1730                1735                1740

 Ala Gly Ser Tyr Ser Gln Pro Ser Ala Thr Phe Ser Leu Ala Lys
                1745                1750                1755

 Leu Gln Gln Leu Thr Asn Thr Ile Met Asp Pro His Ala Met Pro
                1760                1765                1770

 Tyr Ser His Ser Pro Ala Val Thr Ser Tyr Ala Thr Ser Val Ser
                1775                1780                1785

 Leu Ser Asn Thr Gly Leu Ala Gln Leu Ala Pro Ser His Pro Leu
                1790                1795                1800

 Ala Gly Thr Pro Gln Ala Gln Ala Thr Met Thr Pro Pro Pro Asn
                1805                1810                1815

 Leu Ala Ser Thr Thr Met Asn Leu Thr Ser Pro Leu Leu Gln Cys
                1820                1825                1830

 Asn Met Ser Ala Thr Asn Ile Gly Ile Pro His Thr Gln Arg Leu
                1835                1840                1845

 Gln Gly Gln Met Pro Val Lys Gly His Ile Ser Ile Arg Ser Lys
                1850                1855                1860

 Ser Ala Pro Leu Pro Ser Ala Ala Ala His Gln Gln Gln Leu Tyr
                1865                1870                1875

 Gly Arg Ser Pro Ser Ala Val Ala Met Gln Ala Gly Pro Arg Ala
                1880                1885                1890

 Leu Ala Val Gln Arg Gly Met Asn Met Gly Val Asn Leu Met Pro
                1895                1900                1905

 Thr Pro Ala Tyr Asn Val Asn Ser Met Asn Met Asn Thr Leu Asn
                1910                1915                1920

 Ala Met Asn Ser Tyr Arg Met Thr Gln Pro Met Met Asn Ser Ser
                1925                1930                1935

 Tyr His Ser Asn Pro Ala Tyr Met Asn Gln Thr Ala Gln Tyr Pro
                1940                1945                1950

 Met Gln Met Gln Met Gly Met Met Gly Ser Gln Ala Tyr Thr Gln
                1955                1960                1965

 Gln Pro Met Gln Pro Asn Pro His Gly Asn Met Met Tyr Thr Gly
                1970                1975                1980

 Pro Ser His His Ser Tyr Met Asn Ala Ala Gly Val Pro Lys Gln
                1985                1990                1995

 Ser Leu Asn Gly Pro
                2000

<210> 586
<211> 4425
<212> DNA
<213> Homo sapien

<400> 586
 gcgcgcgtgg ggctccattc cgcggtgctg ggtctccgtg ccggggtggg 50

 tgctcgtgtg tgcgcttctc ctccccatcc cccttccccc aagaataaaa 100

 gaagaaccgg gaggcgtgct cagaaaataa ataaataacc accacacacg 150

 cgcagcccgg agcgagtcgg cggggctggc ggcagcggcg gaggaggagt 200

 gaaggcggcg gcggcggagg agggacgcgc ggaaaaggca gcaactttaa 250

 agccagctca gagcctagac ctccagccga gcggtttgca gcgcggcggc 300

 ggcggcggcg gcggcggcgg cggcgttgag tgtctggccc gccggtccgg 350

 tcggggtgtg cagtcggacg gacgagcagc gcgtcgctgt cctccggcag 400

 ctggagatgt ccgagcccaa ggcaattgat cccaagttgt cgacgaccga 450

 cagggtggtg aaagctgttc catttcctcc aagtcaccgg cttacagcaa 500

 aagaagtgtt tgataatgat ggaaaacctc gtgtggatat cttaaaggcg 550

 catcttatga aggagggaag gctggaagag agtgttgcat tgagaataat 600

 aacagagggt gcatcaattc ttcgacagga aaaaaatttg ctggatattg 650

 atgcgccagt cactgtttgt ggggacattc atggacaatt ctttgatttg 700

 atgaagctct ttgaagtcgg gggatctcct gccaacactc gctacctctt 750

 cttaggggac tatgttgaca gagggtactt cagtattgaa tgtgtgctgt 800

 atttgtgggc cttgaaaatt ctctacccca aaacactgtt tttacttcgt 850

 ggaaatcatg aatgtagaca tctaacagag tatttcacat ttaaacaaga 900

 atgtaaaata aagtattcag aacgcgtata tgatgcctgt atggatgcct 950

 ttgactgcct tcccctggct gccctgatga accaacagtt cctgtgtgtg 1000

 catggtggtt tgtctccaga gattaacact ttagatgata tcagaaaatt 1050

 agaccgattc aaagaaccac ctgcatatgg acctatgtgt gatatcctgt 1100

 ggtcagaccc cctggaagat tttggaaatg agaagactca ggaacatttc 1150

 actcacaaca cagtcagggg gtgttcatac ttctacagtt acccggctgt 1200

 atgtgaattc ttacagcaca ataacttgtt atctatactc cgagcccacg 1250

 aagcccaaga tgcagggtac cgcatgtaca ggaaaagcca aacaacaggc 1300

 ttcccttctc taattacaat tttttcagca ccaaattact tagatgtata 1350

 caataacaaa gctgcagtat tgaagtatga gaacaatgtt atgaatatca 1400

 ggcaattcaa ctgttctcct catccatact ggcttccaaa tttcatggat 1450

 gtttttactt ggtcccttcc atttgttggg gaaaaagtga ctgagatgct 1500

 ggtaaatgtc ctcaacatct gctcagatga tgaactaggg tcagaagaag 1550

 atggatttga tggtgcaaca gctgcagccc ggaaagaggt gataaggaac 1600

 aagatccgag caataggcaa aatggccaga gtgttctcag tgctcagaga 1650

 agagagtgag agtgtgctga cgctgaaagg cttgacccca actggcatgc 1700

 tccccagcgg agtactttct ggagggaagc aaaccctgca aagcgctact 1750

 gttgaggcta ttgaggctga tgaagctatc aaaggatttt caccacaaca 1800

 taagatcact agcttcgagg aagccaaggg cttagaccga attaatgaga 1850

 ggatgccgcc tcgcagagat gccatgccct ctgacgccaa ccttaactcc 1900

 atcaacaagg ctctcacctc agagactaac ggcacggaca gcaatggcag 1950

 taatagcagc aatattcagt gaccacttcc tgttcacttt tttttttttt 2000

 tttttttttt tttgagctgc ggggcatgat ggggattgct gcatatcagc 2050

 agttggatgt tcttgcctct gacagtagct tatttgctct gggggccagg 2100

 aattggattc agtttacact atcattaaaa aagagggaga gagataataa 2150

 actatatttt ggtggggatg gtgattaaac acctcttttg ggtatgcctt 2200

 ttaaaaatgc ttatagagaa aaaaatttta aaaagaaagc taatgctagt 2250

 atatactgca atgttagggg aatgaacatg ttttcctact gcattgggga 2300

 cttctagata ggttaatgaa aggcctttta ttctgttact ggacatgaaa 2350

 actttgtcta atttcttact ctattgtacg tttacagtcg cagcactaaa 2400

 aatggatgac atcaaacatt tttaacaaaa tgatgtacaa actaaggact 2450

 atttattgat aatgttttgc tactcttgtc agacaatggc tataaactga 2500

 attaggcagt cttaaaaaaa aaaaaaaaac agaaaaagaa aaaaaagaac 2550

 gttgcaaatt tgttaaaatg ccaaaaagga cagtttaatt ttgtacagat 2600

 tatgcttacc tcaggtttct ttagtgtgct tgaatgccct tctttccata 2650

 taacacttat cttcttctta attcggcaat ggaatatctt ttaagtttta 2700

 aaaaaactgg aataattata tctatctttt ttgccgttta tatttagggg 2750

 tttttgttga taaaatcaag tcttggttgt ggcttgctga attaaatatt 2800

 tatgagtggt gcatttttaa gtatagtgaa caagacacca tattaagtac 2850

 agtgataaag catctatatt ctgtaaaaaa aaaaaaaatc tgcctatgca 2900

 tgttttttaa gaaaaaaaaa atggctgtat cggcctgtat gggactgtaa 2950

 tgcgcttagt ggtctgacat atactggaaa tgtatgtata ctggcgtact 3000

 ttatattctc taaaatgctt aatgcctttg aaattttgta atcaaaaaaa 3050

 agctttgaaa aaatctaaag gggagagtat tctttaaagt ttttaacata 3100

 agcttgtcaa tgcacatgta gatggttagc atgtttagca aaccttgtga 3150

 aattataata agtttgtagt tacatgtgaa actctaaatg catggcaact 3200

 gttaatgtca taacagttta gttattttgt tctgttctgt catgtgccac 3250

 aaaatatgta cttttttcac ttttttccct ttgtatatca gttacgggtt 3300

 acaactggtt cattctgaaa acaacaacaa caaaagtcca ttcatatttt 3350

 ttaacaattg tataagtgcc caagtaattc actacagcct aaagccttgc 3400

 ctttgtaatt tgacttctga catgttggca atcaaagcat gcacttgtaa 3450

 caatgaaaaa gaaaaagcat tttatattac tactcaataa aatgtgcatg 3500

 aacttacaga attctcatcc ttccactgag tccgctgaag ggatttatgt 3550

 gcacaaccac catgtgtctt ctaggtgctg gcccaccacc acacatcaca 3600

 ggctgatttc cacaggcttc ttcctagggg cctcgtgatc tgaggggtgg 3650

 tgcctacttc cactgtaaga aagaatcttg gtggatttgt gtctcaaatc 3700

 agataagaga agcctgttta aagagcagat gccatcttct ggcttcctca 3750

 aggagccagt taaaaaacca gagcattcct ttttattgaa aaataaaatt 3800

 aatttgttat caggttgttt cagttgtatt ggatgcccta tctatctgct 3850

 aaagcaaaaa gtactaggct actaagtgca ttttcatcac agaaaagagt 3900

 tgcatttgta ttaacaagaa atttgtatac ccacgcttca gctactatct 3950

 aatcatcacc cgaagattta agatacacca aatttcagtt tgtttgtaac 4000

 attgttcatc tttagtgcac tttgttttat ataataaagt atgcctgtta 4050

 tattaaataa taagaatatg gcaattagcg atatagcata cccaaacaaa 4100

 gatgttctcg atacagtctg gcaaagacta tcccaaggtt attttaatga 4150

 attcagacat tttttcctgt ggatatttct ccatcctaaa aaaagtggca 4200

 accaaggaaa atatttagat gcaacttact agagtgatga tgtgaaagaa 4250

 atggtgattc tggtatcatg gtgtttattt tctttcttat aactgcagag 4300

 aaaatatcct gactaaaaaa atttcatttt tttggattcc tttcttttac 4350

 aaattgtgct gaggcaacta tggcatagaa ataaacattt gacattaaaa 4400

 taagtaaaaa aaaaaaaaaa aaaaa 4425

<210> 587
<211> 521
<212> PRT
<213> Homo sapien

<400> 587
 Met Ser Glu Pro Lys Ala Ile Asp Pro Lys Leu Ser Thr Thr Asp
   1               5                  10                  15

 Arg Val Val Lys Ala Val Pro Phe Pro Pro Ser His Arg Leu Thr
                  20                  25                  30

 Ala Lys Glu Val Phe Asp Asn Asp Gly Lys Pro Arg Val Asp Ile
                  35                  40                  45

 Leu Lys Ala His Leu Met Lys Glu Gly Arg Leu Glu Glu Ser Val
                  50                  55                  60

 Ala Leu Arg Ile Ile Thr Glu Gly Ala Ser Ile Leu Arg Gln Glu
                  65                  70                  75

 Lys Asn Leu Leu Asp Ile Asp Ala Pro Val Thr Val Cys Gly Asp
                  80                  85                  90

 Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu Val Gly
                  95                 100                 105

 Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr Val
                 110                 115                 120

 Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Ala
                 125                 130                 135

 Leu Lys Ile Leu Tyr Pro Lys Thr Leu Phe Leu Leu Arg Gly Asn
                 140                 145                 150

 His Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu
                 155                 160                 165

 Cys Lys Ile Lys Tyr Ser Glu Arg Val Tyr Asp Ala Cys Met Asp
                 170                 175                 180

 Ala Phe Asp Cys Leu Pro Leu Ala Ala Leu Met Asn Gln Gln Phe
                 185                 190                 195

 Leu Cys Val His Gly Gly Leu Ser Pro Glu Ile Asn Thr Leu Asp
                 200                 205                 210

 Asp Ile Arg Lys Leu Asp Arg Phe Lys Glu Pro Pro Ala Tyr Gly
                 215                 220                 225

 Pro Met Cys Asp Ile Leu Trp Ser Asp Pro Leu Glu Asp Phe Gly
                 230                 235                 240

 Asn Glu Lys Thr Gln Glu His Phe Thr His Asn Thr Val Arg Gly
                 245                 250                 255

 Cys Ser Tyr Phe Tyr Ser Tyr Pro Ala Val Cys Glu Phe Leu Gln
                 260                 265                 270

 His Asn Asn Leu Leu Ser Ile Leu Arg Ala His Glu Ala Gln Asp
                 275                 280                 285

 Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln Thr Thr Gly Phe Pro
                 290                 295                 300

 Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr Leu Asp Val Tyr
                 305                 310                 315

 Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn Val Met Asn
                 320                 325                 330

 Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu Pro Asn
                 335                 340                 345

 Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu Lys
                 350                 355                 360

 Val Thr Glu Met Leu Val Asn Val Leu Asn Ile Cys Ser Asp Asp
                 365                 370                 375

 Glu Leu Gly Ser Glu Glu Asp Gly Phe Asp Gly Ala Thr Ala Ala
                 380                 385                 390

 Ala Arg Lys Glu Val Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys
                 395                 400                 405

 Met Ala Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val
                 410                 415                 420

 Leu Thr Leu Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly
                 425                 430                 435

 Val Leu Ser Gly Gly Lys Gln Thr Leu Gln Ser Ala Thr Val Glu
                 440                 445                 450

 Ala Ile Glu Ala Asp Glu Ala Ile Lys Gly Phe Ser Pro Gln His
                 455                 460                 465

 Lys Ile Thr Ser Phe Glu Glu Ala Lys Gly Leu Asp Arg Ile Asn
                 470                 475                 480

 Glu Arg Met Pro Pro Arg Arg Asp Ala Met Pro Ser Asp Ala Asn
                 485                 490                 495

 Leu Asn Ser Ile Asn Lys Ala Leu Thr Ser Glu Thr Asn Gly Thr
                 500                 505                 510

 Asp Ser Asn Gly Ser Asn Ser Ser Asn Ile Gln
                 515                 520

<210> 588
<211> 2077
<212> DNA
<213> Homo sapien

<400> 588
 ccgagcgcca gcgcggggaa ccgggaaaag gaaaccgtgt tgtgtacgta 50

 agattcagga aacgaaacca ggagccgcgg gtgttggcgc aaaggttact 100

 cccagaccct tttccggctg acttctgaga aggttgcgca cagctgtgcc 150

 cggcagtcta gaggcgcaga agaggaagcc atcgcctggc cccggctctc 200

 tggaccttgt ctcgctcggg agcggaaaca gcggcagcca gagaactgtt 250

 ttaatcatgg acaaacaaaa ctcacagatg aatgcttctc acccggaaac 300

 aaacttgcca gttgggtatc ctcctcagta tccaccgaca gcattccaag 350

 gacctccagg atatagtggc taccctgggc cccaggtcag ctacccaccc 400

 ccaccagccg gccattcagg tcctggccca gctggctttc ctgtcccaaa 450

 tcagccagtg tataatcagc cagtatataa tcagccagtt ggagctgcag 500

 gggtaccatg gatgccagcg ccacagcctc cattaaactg tccacctgga 550

 ttagaatatt taagtcagat agatcagata ctgattcatc agcaaattga 600

 acttctggaa gttttaacag gttttgaaac taataacaaa tatgaaatta 650

 agaacagctt tggacagagg gtttactttg cagcggaaga tactgattgc 700

 tgtacccgaa attgctgtgg gccatctaga ccttttacct tgaggattat 750

 tgataatatg ggtcaagaag tcataactct ggagagacca ctaagatgta 800

 gcagctgttg ttgtccctgc tgccttcagg agatagaaat ccaagctcct 850

 cctggtgtac caataggtta tgttattcag acttggcacc catgtctacc 900

 aaagtttaca attcaaaatg agaaaagaga ggatgtacta aaaataagtg 950

 gtccatgtgt tgtgtgcagc tgttgtggag atgttgattt tgagattaaa 1000

 tctcttgatg aacagtgtgt ggttggcaaa atttccaagc actggactgg 1050

 aattttgaga gaggcattta cagacgctga taactttgga atccagttcc 1100

 ctttagacct tgatgttaaa atgaaagctg taatgattgg tgcctgtttc 1150

 ctcattgact tcatgttttt tgaaagcact ggcagccagg aacaaaaatc 1200

 aggagtgtgg tagtggatta gtgaaagtct cctcaggaaa tctgaagtct 1250

 gtatattgat tgagactatc taaactcata cctgtatgaa ttaagctgta 1300

 aggcctgtag ctctggttgt atacttttgc ttttcaaatt atagtttatc 1350

 ttctgtataa ctgatttata aaggtttttg tacatttttt aatactcatt 1400

 gtcaatttga gaaaaaggac atatgagttt ttgcatttat taatgaaact 1450

 tcctttgaaa aactgctttg aattatgatc tctgattcat tgtccatttt 1500

 actaccaaat attaactaag gccttattaa tttttatata aattatatct 1550

 tgtcctatta aatctagtta caatttattt catgcataag agctaatgtt 1600

 attttgcaaa tgccatatat tcaaaaaagc tcaaagataa ttttctttac 1650

 tattatgttc aaataatatt caatatgcat attatcttta aaaagttaaa 1700

 tgttttttta atcttcaaga aatcatgcta cacttaactt ctcctagaag 1750

 ctaatctata ccataatatt ttcatattca caagatatta aattaccaat 1800

 tttcaaatta ttgttagtaa agaacaaaat gattctctcc caaagaaaga 1850

 cacattttaa atactccttc actctaaaac tctggtatta taacttttga 1900

 aagttaatat ttctacatga aatgtttagc tcttacactc tatccttcct 1950

 agaaaatggt aattgagatt actcagatat taattaaata caatatcata 2000

 tatatattca cagagtataa acctaaataa tgatctatta gattcaaata 2050

 tttgaaataa aaacttgatt tttttgt 2077

<210> 589
<211> 318
<212> PRT
<213> Homo sapien

<400> 589
 Met Asp Lys Gln Asn Ser Gln Met Asn Ala Ser His Pro Glu Thr
   1               5                  10                  15

 Asn Leu Pro Val Gly Tyr Pro Pro Gln Tyr Pro Pro Thr Ala Phe
                  20                  25                  30

 Gln Gly Pro Pro Gly Tyr Ser Gly Tyr Pro Gly Pro Gln Val Ser
                  35                  40                  45

 Tyr Pro Pro Pro Pro Ala Gly His Ser Gly Pro Gly Pro Ala Gly
                  50                  55                  60

 Phe Pro Val Pro Asn Gln Pro Val Tyr Asn Gln Pro Val Tyr Asn
                  65                  70                  75

 Gln Pro Val Gly Ala Ala Gly Val Pro Trp Met Pro Ala Pro Gln
                  80                  85                  90

 Pro Pro Leu Asn Cys Pro Pro Gly Leu Glu Tyr Leu Ser Gln Ile
                  95                 100                 105

 Asp Gln Ile Leu Ile His Gln Gln Ile Glu Leu Leu Glu Val Leu
                 110                 115                 120

 Thr Gly Phe Glu Thr Asn Asn Lys Tyr Glu Ile Lys Asn Ser Phe
                 125                 130                 135

 Gly Gln Arg Val Tyr Phe Ala Ala Glu Asp Thr Asp Cys Cys Thr
                 140                 145                 150

 Arg Asn Cys Cys Gly Pro Ser Arg Pro Phe Thr Leu Arg Ile Ile
                 155                 160                 165

 Asp Asn Met Gly Gln Glu Val Ile Thr Leu Glu Arg Pro Leu Arg
                 170                 175                 180

 Cys Ser Ser Cys Cys Cys Pro Cys Cys Leu Gln Glu Ile Glu Ile
                 185                 190                 195

 Gln Ala Pro Pro Gly Val Pro Ile Gly Tyr Val Ile Gln Thr Trp
                 200                 205                 210

 His Pro Cys Leu Pro Lys Phe Thr Ile Gln Asn Glu Lys Arg Glu
                 215                 220                 225

 Asp Val Leu Lys Ile Ser Gly Pro Cys Val Val Cys Ser Cys Cys
                 230                 235                 240

 Gly Asp Val Asp Phe Glu Ile Lys Ser Leu Asp Glu Gln Cys Val
                 245                 250                 255

 Val Gly Lys Ile Ser Lys His Trp Thr Gly Ile Leu Arg Glu Ala
                 260                 265                 270

 Phe Thr Asp Ala Asp Asn Phe Gly Ile Gln Phe Pro Leu Asp Leu
                 275                 280                 285

 Asp Val Lys Met Lys Ala Val Met Ile Gly Ala Cys Phe Leu Ile
                 290                 295                 300

 Asp Phe Met Phe Phe Glu Ser Thr Gly Ser Gln Glu Gln Lys Ser
                 305                 310                 315

 Gly Val Trp


<210> 590
<211> 2121
<212> DNA
<213> Homo sapien

<400> 590
 ctgctcgcgg ccgccaccgc cgggccccgg ccgtccctgg ctcccctcct 50

 gcctcgagaa gggcagggct tctcagaggc ttggcgggaa aaaagaacgg 100

 agggagggat cgcgctgagt ataaaagccg gttttcgggg ctttatctaa 150

 ctcgctgtag taattccagc gagaggcaga gggagcgagc gggcggccgg 200

 ctagggtgga agagccgggc gagcagagct gcgctgcggg cgtcctggga 250

 agggagatcc ggagcgaata gggggcttcg cctctggccc agccctcccg 300

 cttgatcccc caggccagcg gtccgcaacc cttgccgcat ccacgaaact 350

 ttgcccatag cagcgggcgg gcactttgca ctggaactta caacacccga 400

 gcaaggacgc gactctcccg acgcggggag gctattctgc ccatttgggg 450

 acacttcccc gccgctgcca ggacccgctt ctctgaaagg ctctccttgc 500

 agctgcttag acgctggatt tttttcgggt agtggaaaac cagcagcctc 550

 ccgcgacgat gcccctcaac gttagcttca ccaacaggaa ctatgacctc 600

 gactacgact cggtgcagcc gtatttctac tgcgacgagg aggagaactt 650

 ctaccagcag cagcagcaga gcgagctgca gcccccggcg cccagcgagg 700

 atatctggaa gaaattcgag ctgctgccca ccccgcccct gtcccctagc 750

 cgccgctccg ggctctgctc gccctcctac gttgcggtca cacccttctc 800

 ccttcgggga gacaacgacg gcggtggcgg gagcttctcc acggccgacc 850

 agctggagat ggtgaccgag ctgctgggag gagacatggt gaaccagagt 900

 ttcatctgcg acccggacga cgagaccttc atcaaaaaca tcatcatcca 950

 ggactgtatg tggagcggct tctcggccgc cgccaagctc gtctcagaga 1000

 agctggcctc ctaccaggct gcgcgcaaag acagcggcag cccgaacccc 1050

 gcccgcggcc acagcgtctg ctccacctcc agcttgtacc tgcaggatct 1100

 gagcgccgcc gcctcagagt gcatcgaccc ctcggtggtc ttcccctacc 1150

 ctctcaacga cagcagctcg cccaagtcct gcgcctcgca agactccagc 1200

 gccttctctc cgtcctcgga ttctctgctc tcctcgacgg agtcctcccc 1250

 gcagggcagc cccgagcccc tggtgctcca tgaggagaca ccgcccacca 1300

 ccagcagcga ctctgaggag gaacaagaag atgaggaaga aatcgatgtt 1350

 gtttctgtgg aaaagaggca ggctcctggc aaaaggtcag agtctggatc 1400

 accttctgct ggaggccaca gcaaacctcc tcacagccca ctggtcctca 1450

 agaggtgcca cgtctccaca catcagcaca actacgcagc gcctccctcc 1500

 actcggaagg actatcctgc tgccaagagg gtcaagttgg acagtgtcag 1550

 agtcctgaga cagatcagca acaaccgaaa atgcaccagc cccaggtcct 1600

 cggacaccga ggagaatgtc aagaggcgaa cacacaacgt cttggagcgc 1650

 cagaggagga acgagctaaa acggagcttt tttgccctgc gtgaccagat 1700

 cccggagttg gaaaacaatg aaaaggcccc caaggtagtt atccttaaaa 1750

 aagccacagc atacatcctg tccgtccaag cagaggagca aaagctcatt 1800

 tctgaagagg acttgttgcg gaaacgacga gaacagttga aacacaaact 1850

 tgaacagcta cggaactctt gtgcgtaagg aaaagtaagg aaaacgattc 1900

 cttctaacag aaatgtcctg agcaatcacc tatgaacttg tttcaaatgc 1950

 atgatcaaat gcaacctcac aaccttggct gagtcttgag actgaaagat 2000

 ttagccataa tgtaaactgc ctcaaattgg actttgggca taaaagaact 2050

 tttttatgct taccatcttt tttttttctt taacagattt gtatttaaga 2100

 attgttttta aaaaatttta a 2121

<210> 591
<211> 439
<212> PRT
<213> Homo sapien

<400> 591
 Met Pro Leu Asn Val Ser Phe Thr Asn Arg Asn Tyr Asp Leu Asp
   1               5                  10                  15

 Tyr Asp Ser Val Gln Pro Tyr Phe Tyr Cys Asp Glu Glu Glu Asn
                  20                  25                  30

 Phe Tyr Gln Gln Gln Gln Gln Ser Glu Leu Gln Pro Pro Ala Pro
                  35                  40                  45

 Ser Glu Asp Ile Trp Lys Lys Phe Glu Leu Leu Pro Thr Pro Pro
                  50                  55                  60

 Leu Ser Pro Ser Arg Arg Ser Gly Leu Cys Ser Pro Ser Tyr Val
                  65                  70                  75

 Ala Val Thr Pro Phe Ser Leu Arg Gly Asp Asn Asp Gly Gly Gly
                  80                  85                  90

 Gly Ser Phe Ser Thr Ala Asp Gln Leu Glu Met Val Thr Glu Leu
                  95                 100                 105

 Leu Gly Gly Asp Met Val Asn Gln Ser Phe Ile Cys Asp Pro Asp
                 110                 115                 120

 Asp Glu Thr Phe Ile Lys Asn Ile Ile Ile Gln Asp Cys Met Trp
                 125                 130                 135

 Ser Gly Phe Ser Ala Ala Ala Lys Leu Val Ser Glu Lys Leu Ala
                 140                 145                 150

 Ser Tyr Gln Ala Ala Arg Lys Asp Ser Gly Ser Pro Asn Pro Ala
                 155                 160                 165

 Arg Gly His Ser Val Cys Ser Thr Ser Ser Leu Tyr Leu Gln Asp
                 170                 175                 180

 Leu Ser Ala Ala Ala Ser Glu Cys Ile Asp Pro Ser Val Val Phe
                 185                 190                 195

 Pro Tyr Pro Leu Asn Asp Ser Ser Ser Pro Lys Ser Cys Ala Ser
                 200                 205                 210

 Gln Asp Ser Ser Ala Phe Ser Pro Ser Ser Asp Ser Leu Leu Ser
                 215                 220                 225

 Ser Thr Glu Ser Ser Pro Gln Gly Ser Pro Glu Pro Leu Val Leu
                 230                 235                 240

 His Glu Glu Thr Pro Pro Thr Thr Ser Ser Asp Ser Glu Glu Glu
                 245                 250                 255

 Gln Glu Asp Glu Glu Glu Ile Asp Val Val Ser Val Glu Lys Arg
                 260                 265                 270

 Gln Ala Pro Gly Lys Arg Ser Glu Ser Gly Ser Pro Ser Ala Gly
                 275                 280                 285

 Gly His Ser Lys Pro Pro His Ser Pro Leu Val Leu Lys Arg Cys
                 290                 295                 300

 His Val Ser Thr His Gln His Asn Tyr Ala Ala Pro Pro Ser Thr
                 305                 310                 315

 Arg Lys Asp Tyr Pro Ala Ala Lys Arg Val Lys Leu Asp Ser Val
                 320                 325                 330

 Arg Val Leu Arg Gln Ile Ser Asn Asn Arg Lys Cys Thr Ser Pro
                 335                 340                 345

 Arg Ser Ser Asp Thr Glu Glu Asn Val Lys Arg Arg Thr His Asn
                 350                 355                 360

 Val Leu Glu Arg Gln Arg Arg Asn Glu Leu Lys Arg Ser Phe Phe
                 365                 370                 375

 Ala Leu Arg Asp Gln Ile Pro Glu Leu Glu Asn Asn Glu Lys Ala
                 380                 385                 390

 Pro Lys Val Val Ile Leu Lys Lys Ala Thr Ala Tyr Ile Leu Ser
                 395                 400                 405

 Val Gln Ala Glu Glu Gln Lys Leu Ile Ser Glu Glu Asp Leu Leu
                 410                 415                 420

 Arg Lys Arg Arg Glu Gln Leu Lys His Lys Leu Glu Gln Leu Arg
                 425                 430                 435

 Asn Ser Cys Ala


<210> 592
<211> 5128
<212> DNA
<213> Homo sapien

<400> 592
 actctggagt gggagtggga gcgagcgctt ctgcgactcc agttgtgaga 50

 gccgcaaggg catgggaatt gacgccactc accgaccccc agtctcaatc 100

 tcaacgctgt gaggaaacct cgactttgcc aggtccccaa gggcagcggg 150

 gctcggcgag cgaggcaccc ttctccgtcc ccatcccaat ccaagcgctc 200

 ctggcactga cgacgccaag agactcgagt gggagttaaa gcttccagtg 250

 agggcagcag gtgtccaggc cgggcctgcg ggttcctgtt gacgtcttgc 300

 cctaggcaaa ggtcccagtt ccttctcgga gccggctgtc ccgcgccact 350

 ggaaaccgca cctccccgca gcatgggcac cagcctcagc ccgaacgacc 400

 cttggccgct aaacccgctg tccatccagc agaccacgct cctgctactc 450

 ctgtcggtgc tggccactgt gcatgtgggc cagcggctgc tgaggcaacg 500

 gaggcggcag ctccggtccg cgcccccggg cccgtttgcg tggccactga 550

 tcggaaacgc ggcggcggtg ggccaggcgg ctcacctctc gttcgctcgc 600

 ctggcgcggc gctacggcga cgttttccag atccgcctgg gcagctgccc 650

 catagtggtg ctgaatggcg agcgcgccat ccaccaggcc ctggtgcagc 700

 agggctcggc cttcgccgac cggccggcct tcgcctcctt ccgtgtggtg 750

 tccggcggcc gcagcatggc tttcggccac tactcggagc actggaaggt 800

 gcagcggcgc gcagcccaca gcatgatgcg caacttcttc acgcgccagc 850

 cgcgcagccg ccaagtcctc gagggccacg tgctgagcga ggcgcgcgag 900

 ctggtggcgc tgctggtgcg cggcagcgcg gacggcgcct tcctcgaccc 950

 gaggccgctg accgtcgtgg ccgtggccaa cgtcatgagt gccgtgtgtt 1000

 tcggctgccg ctacagccac gacgaccccg agttccgtga gctgctcagc 1050

 cacaacgaag agttcgggcg cacggtgggc gcgggcagcc tggtggacgt 1100

 gatgccctgg ctgcagtact tccccaaccc ggtgcgcacc gttttccgcg 1150

 aattcgagca gctcaaccgc aacttcagca acttcatcct ggacaagttc 1200

 ttgaggcact gcgaaagcct tcggcccggg gccgcccccc gcgacatgat 1250

 ggacgccttt atcctctctg cggaaaagaa ggcggccggg gactcgcacg 1300

 gtggtggcgc gcggctggat ttggagaacg taccggccac tatcactgac 1350

 atcttcggcg ccagccagga caccctgtcc accgcgctgc agtggctgct 1400

 cctcctcttc accaggtatc ctgatgtgca gactcgagtg caggcagaat 1450

 tggatcaggt cgtggggagg gaccgtctgc cttgtatggg tgaccagccc 1500

 aacctgccct atgtcctggc cttcctttat gaagccatgc gcttctccag 1550

 ctttgtgcct gtcactattc ctcatgccac cactgccaac acctctgtct 1600

 tgggctacca cattcccaag gacactgtgg tttttgtcaa ccagtggtct 1650

 gtgaatcatg acccagtgaa gtggcctaac ccggagaact ttgatccagc 1700

 tcgattcttg gacaaggatg gcctcatcaa caaggacctg accagcagag 1750

 tgatgatttt ttcagtgggc aaaaggcggt gcattggcga agaactttct 1800

 aagatgcagc tttttctctt catctccatc ctggctcacc agtgcgattt 1850

 cagggccaac ccaaatgagc ctgcgaaaat gaatttcagt tatggtctaa 1900

 ccattaaacc caagtcattt aaagtcaatg tcactctcag agagtccatg 1950

 gagctccttg atagtgctgt ccaaaattta caagccaagg aaacttgcca 2000

 ataagaagca agaggcaagc tgaaatttta gaaatattca catcttcgga 2050

 gatgaggagt aaaattcagt ttttttccag ttcctctttt gtgctgcttc 2100

 tcaattagcg tttaaggtga gcataaatca actgtccatc aggtgaggtg 2150

 tgctccatac ccagcggttc ttcatgagta gtgggctatg caggagcttc 2200

 tgggagattt ttttgagtca aagacttaaa gggcccaatg aattattata 2250

 tacatactgc atcttggtta tttctgaagg tagcattctt tggagttaaa 2300

 atgcacatat agacacatac acccaaacac ttacaccaaa ctactgaatg 2350

 aagaagtatt ttggtaacca ggccattttt ggtgggaatc caagattggt 2400

 ctcccatatg cagaaataga caaaaagtat attaaacaaa gtttcagagt 2450

 atattgttga agagacagag acaagtaatt tcagtgtaaa gtgtgtgatt 2500

 gaaggtgata agggaaaaga taaagaccag aaattccctt ttcacctttt 2550

 caggaaaata acttagactc tagtatttat gggtggattt atccttttgc 2600

 cttctggtat acttccttac ttttaaggat aaatcataaa gtcagttgct 2650

 caaaaagaaa tcaatagttg aattagtgag tatagtgggg ttccatgagt 2700

 tatcatgaat tttaaagtat gcattattaa attgtaaaac tccaaggtga 2750

 tgttgtacct cttttgcttg ccaaagtaca gaatttgaat tatcagcaaa 2800

 gaaaaaaaaa aaagccagcc aagctttaaa ttatgtgacc ataatgtact 2850

 gatttcagta agtctcatag gttaaaaaaa aaagtcacca aatagtgtga 2900

 aatatattac ttaactgtcc gtaagcagta tattagtatt atcttgttca 2950

 ggaaaaggtt gaataatata tgccttgtgt aatattgaaa attgaaaagt 3000

 acaactaacg caaccaagtg tgctaaaaat gagcttgatt aaatcaacca 3050

 cctatttttg acatggaaat gaagcagggt ttcttttctt cactcaaatt 3100

 ttggcgaatc tcaaaattag atcctaagat gtgttcttat ttttataaca 3150

 tctttattga aattctattt ataatacaga atcttgtttt gaaaataacc 3200

 taattaatat attaaaattc caaattcatg gcatgcttaa attttaacta 3250

 aattttaaag ccattctgat tattgagttc cagttgaagt tagtggaaat 3300

 ctgaacattc tcctgtggaa ggcagagaaa tctaagctgt gtctgcccaa 3350

 tgaataatgg aaaatgccat gaattacctg gatgttcttt ttacgaggtg 3400

 acaagagttg gggacagaac tcccattaca actgaccaag tttctcttct 3450

 agatgatttt ttgaaagtta acattaatgc ctgctttttg gaaagtcaga 3500

 atcagaagat agtcttggaa gctgtttgga aaagacagtg gagatgaggt 3550

 cagttgtgtt ttttaagatg gcaattactt tggtagctgg gaaagcataa 3600

 agctcaaatg aaatgtatgc attcacattt agaaaagtga attgaagttt 3650

 caagttttaa agttcattgc aattaaactt ccaaagaaag ttctacagtg 3700

 tcctaagtgc taagtgctta ttacatttta ttaagctttt tggaatcttt 3750

 gtaccaaaat tttaaaaaag ggagtttttg atagttgtgt gtatgtgtgt 3800

 gtggggtggg gggatggtaa gagaaaagag agaaacactg aaaagaagga 3850

 aagatggtta aacattttcc cactcattct gaattaatta atttggagca 3900

 caaaattcaa agcatggaca tttagaagaa agatgtttgg cgtagcagag 3950

 ttaaatctca aataggctat taaaaaagtc tacaacatag cagatctgtt 4000

 ttgtggtttg gaatattaaa aaacttcatg taattttatt ttaaaatttc 4050

 atagctgtac ttcttgaata taaaaaatca tgccagtatt tttaaaggca 4100

 ttagagtcaa ctacacaaag caggcttgcc cagtacattt aaattttttg 4150

 gcacttgcca ttccaaaata ttatgcccca ccaaggctga gacagtgaat 4200

 ttgggctgct gtagcctatt tttttagatt gagaaatgtg tagctgcaaa 4250

 aataatcatg aaccaatctg gatgcctcat tatgtcaacc aggtccagat 4300

 gtgctataat ctgtttttac gtatgtaggc ccagtcgtca tcagatgctt 4350

 gcggcaaaag aaagctgtgt ttatatggaa gaaagtaagg tgcttggagt 4400

 ttacctggct tatttaatat gcttataacc tagttaaaga aaggaaaaga 4450

 aaacaaaaaa cgaatgaaaa taactgaatt tggaggctgg agtaatcaga 4500

 ttactgcttt aatcagaaac cctcattgtg tttctaccgg agagagaatg 4550

 tatttgctga caaccattaa agtcagaagt tttactccag gttattgcaa 4600

 taaagtataa tgtttattaa atgcttcatt tgtatgtcaa agctttgact 4650

 ctataagcaa attgcttttt tccaaaacaa aaagatgtct caggtttgtt 4700

 ttgtgaattt tctaaaagct ttcatgtccc agaacttagc ctttacctgt 4750

 gaagtgttac tacagcctta atattttcct agtagatcta tattagatca 4800

 aatagttgca tagcagtata tgttaatttg tgtgttttta gctgtgacac 4850

 aactgtgtga ttaaaaggta tactttagta gacatttata actcaaggat 4900

 accttcttat ttaatctttt cttatttttg tactttatca tgaatgcttt 4950

 tagtgtgtgc ataatagcta cagtgcatag ttgtagacaa agtacattct 5000

 ggggaaacaa catttatatg tagcctttac tgtttgatat accaaattaa 5050

 aaaaaaattg tatctcatta cttatactgg gacaccatta ccaaaataat 5100

 aaaaatcact ttcataatct tgaaaaaa 5128

<210> 593
<211> 543
<212> PRT
<213> Homo sapien

<400> 593
 Met Gly Thr Ser Leu Ser Pro Asn Asp Pro Trp Pro Leu Asn Pro
   1               5                  10                  15

 Leu Ser Ile Gln Gln Thr Thr Leu Leu Leu Leu Leu Ser Val Leu
                  20                  25                  30

 Ala Thr Val His Val Gly Gln Arg Leu Leu Arg Gln Arg Arg Arg
                  35                  40                  45

 Gln Leu Arg Ser Ala Pro Pro Gly Pro Phe Ala Trp Pro Leu Ile
                  50                  55                  60

 Gly Asn Ala Ala Ala Val Gly Gln Ala Ala His Leu Ser Phe Ala
                  65                  70                  75

 Arg Leu Ala Arg Arg Tyr Gly Asp Val Phe Gln Ile Arg Leu Gly
                  80                  85                  90

 Ser Cys Pro Ile Val Val Leu Asn Gly Glu Arg Ala Ile His Gln
                  95                 100                 105

 Ala Leu Val Gln Gln Gly Ser Ala Phe Ala Asp Arg Pro Ala Phe
                 110                 115                 120

 Ala Ser Phe Arg Val Val Ser Gly Gly Arg Ser Met Ala Phe Gly
                 125                 130                 135

 His Tyr Ser Glu His Trp Lys Val Gln Arg Arg Ala Ala His Ser
                 140                 145                 150

 Met Met Arg Asn Phe Phe Thr Arg Gln Pro Arg Ser Arg Gln Val
                 155                 160                 165

 Leu Glu Gly His Val Leu Ser Glu Ala Arg Glu Leu Val Ala Leu
                 170                 175                 180

 Leu Val Arg Gly Ser Ala Asp Gly Ala Phe Leu Asp Pro Arg Pro
                 185                 190                 195

 Leu Thr Val Val Ala Val Ala Asn Val Met Ser Ala Val Cys Phe
                 200                 205                 210

 Gly Cys Arg Tyr Ser His Asp Asp Pro Glu Phe Arg Glu Leu Leu
                 215                 220                 225

 Ser His Asn Glu Glu Phe Gly Arg Thr Val Gly Ala Gly Ser Leu
                 230                 235                 240

 Val Asp Val Met Pro Trp Leu Gln Tyr Phe Pro Asn Pro Val Arg
                 245                 250                 255

 Thr Val Phe Arg Glu Phe Glu Gln Leu Asn Arg Asn Phe Ser Asn
                 260                 265                 270

 Phe Ile Leu Asp Lys Phe Leu Arg His Cys Glu Ser Leu Arg Pro
                 275                 280                 285

 Gly Ala Ala Pro Arg Asp Met Met Asp Ala Phe Ile Leu Ser Ala
                 290                 295                 300

 Glu Lys Lys Ala Ala Gly Asp Ser His Gly Gly Gly Ala Arg Leu
                 305                 310                 315

 Asp Leu Glu Asn Val Pro Ala Thr Ile Thr Asp Ile Phe Gly Ala
                 320                 325                 330

 Ser Gln Asp Thr Leu Ser Thr Ala Leu Gln Trp Leu Leu Leu Leu
                 335                 340                 345

 Phe Thr Arg Tyr Pro Asp Val Gln Thr Arg Val Gln Ala Glu Leu
                 350                 355                 360

 Asp Gln Val Val Gly Arg Asp Arg Leu Pro Cys Met Gly Asp Gln
                 365                 370                 375

 Pro Asn Leu Pro Tyr Val Leu Ala Phe Leu Tyr Glu Ala Met Arg
                 380                 385                 390

 Phe Ser Ser Phe Val Pro Val Thr Ile Pro His Ala Thr Thr Ala
                 395                 400                 405

 Asn Thr Ser Val Leu Gly Tyr His Ile Pro Lys Asp Thr Val Val
                 410                 415                 420

 Phe Val Asn Gln Trp Ser Val Asn His Asp Pro Val Lys Trp Pro
                 425                 430                 435

 Asn Pro Glu Asn Phe Asp Pro Ala Arg Phe Leu Asp Lys Asp Gly
                 440                 445                 450

 Leu Ile Asn Lys Asp Leu Thr Ser Arg Val Met Ile Phe Ser Val
                 455                 460                 465

 Gly Lys Arg Arg Cys Ile Gly Glu Glu Leu Ser Lys Met Gln Leu
                 470                 475                 480

 Phe Leu Phe Ile Ser Ile Leu Ala His Gln Cys Asp Phe Arg Ala
                 485                 490                 495

 Asn Pro Asn Glu Pro Ala Lys Met Asn Phe Ser Tyr Gly Leu Thr
                 500                 505                 510

 Ile Lys Pro Lys Ser Phe Lys Val Asn Val Thr Leu Arg Glu Ser
                 515                 520                 525

 Met Glu Leu Leu Asp Ser Ala Val Gln Asn Leu Gln Ala Lys Glu
                 530                 535                 540

 Thr Cys Gln


<210> 594
<211> 5128
<212> DNA
<213> Homo sapien

<400> 594
 actctggagt gggagtggga gcgagcgctt ctgcgactcc agttgtgaga 50

 gccgcaaggg catgggaatt gacgccactc accgaccccc agtctcaatc 100

 tcaacgctgt gaggaaacct cgactttgcc aggtccccaa gggcagcggg 150

 gctcggcgag cgaggcaccc ttctccgtcc ccatcccaat ccaagcgctc 200

 ctggcactga cgacgccaag agactcgagt gggagttaaa gcttccagtg 250

 agggcagcag gtgtccaggc cgggcctgcg ggttcctgtt gacgtcttgc 300

 cctaggcaaa ggtcccagtt ccttctcgga gccggctgtc ccgcgccact 350

 ggaaaccgca cctccccgca gcatgggcac cagcctcagc ccgaacgacc 400

 cttggccgct aaacccgctg tccatccagc agaccacgct cctgctactc 450

 ctgtcggtgc tggccactgt gcatgtgggc cagcggctgc tgaggcaacg 500

 gaggcggcag ctccggtccg cgcccccggg cccgtttgcg tggccactga 550

 tcggaaacgc ggcggcggtg ggccaggcgg ctcacctctc gttcgctcgc 600

 ctggcgcggc gctacggcga cgttttccag atccgcctgg gcagctgccc 650

 catagtggtg ctgaatggcg agcgcgccat ccaccaggcc ctggtgcagc 700

 agggctcggc cttcgccgac cggccggcct tcgcctcctt ccgtgtggtg 750

 tccggcggcc gcagcatggc tttcggccac tactcggagc actggaaggt 800

 gcagcggcgc gcagcccaca gcatgatgcg caacttcttc acgcgccagc 850

 cgcgcagccg ccaagtcctc gagggccacg tgctgagcga ggcgcgcgag 900

 ctggtggcgc tgctggtgcg cggcagcgcg gacggcgcct tcctcgaccc 950

 gaggccgctg accgtcgtgg ccgtggccaa cgtcatgagt gccgtgtgtt 1000

 tcggctgccg ctacagccac gacgaccccg agttccgtga gctgctcagc 1050

 cacaacgaag agttcgggcg cacggtgggc gcgggcagcc tggtggacgt 1100

 gatgccctgg ctgcagtact tccccaaccc ggtgcgcacc gttttccgcg 1150

 aattcgagca gctcaaccgc aacttcagca acttcatcct ggacaagttc 1200

 ttgaggcact gcgaaagcct tcggcccggg gccgcccccc gcgacatgat 1250

 ggacgccttt atcctctctg cggaaaagaa ggcggccggg gactcgcacg 1300

 gtggtggcgc gcggctggat ttggagaacg taccggccac tatcactgac 1350

 atcttcggcg ccagccagga caccctgtcc accgcgctgc agtggctgct 1400

 cctcctcttc accaggtatc ctgatgtgca gactcgagtg caggcagaat 1450

 tggatcaggt cgtggggagg gaccgtctgc cttgtatggg tgaccagccc 1500

 aacctgccct atgtcctggc cttcctttat gaagccatgc gcttctccag 1550

 ctttgtgcct gtcactattc ctcatgccac cactgccaac acctctgtct 1600

 tgggctacca cattcccaag gacactgtgg tttttgtcaa ccagtggtct 1650

 gtgaatcatg acccagtgaa gtggcctaac ccggagaact ttgatccagc 1700

 tcgattcttg gacaaggatg gcctcatcaa caaggacctg accagcagag 1750

 tgatgatttt ttcagtgggc aaaaggcggt gcattggcga agaactttct 1800

 aagatgcagc tttttctctt catctccatc ctggctcacc agtgcgattt 1850

 cagggccaac ccaaatgagc ctgcgaaaat gaatttcagt tatggtctaa 1900

 ccattaaacc caagtcattt aaagtcaatg tcactctcag agagtccatg 1950

 gagctccttg atagtgctgt ccaaaattta caagccaagg aaacttgcca 2000

 ataagaagca agaggcaagc tgaaatttta gaaatattca catcttcgga 2050

 gatgaggagt aaaattcagt ttttttccag ttcctctttt gtgctgcttc 2100

 tcaattagcg tttaaggtga gcataaatca actgtccatc aggtgaggtg 2150

 tgctccatac ccagcggttc ttcatgagta gtgggctatg caggagcttc 2200

 tgggagattt ttttgagtca aagacttaaa gggcccaatg aattattata 2250

 tacatactgc atcttggtta tttctgaagg tagcattctt tggagttaaa 2300

 atgcacatat agacacatac acccaaacac ttacaccaaa ctactgaatg 2350

 aagaagtatt ttggtaacca ggccattttt ggtgggaatc caagattggt 2400

 ctcccatatg cagaaataga caaaaagtat attaaacaaa gtttcagagt 2450

 atattgttga agagacagag acaagtaatt tcagtgtaaa gtgtgtgatt 2500

 gaaggtgata agggaaaaga taaagaccag aaattccctt ttcacctttt 2550

 caggaaaata acttagactc tagtatttat gggtggattt atccttttgc 2600

 cttctggtat acttccttac ttttaaggat aaatcataaa gtcagttgct 2650

 caaaaagaaa tcaatagttg aattagtgag tatagtgggg ttccatgagt 2700

 tatcatgaat tttaaagtat gcattattaa attgtaaaac tccaaggtga 2750

 tgttgtacct cttttgcttg ccaaagtaca gaatttgaat tatcagcaaa 2800

 gaaaaaaaaa aaagccagcc aagctttaaa ttatgtgacc ataatgtact 2850

 gatttcagta agtctcatag gttaaaaaaa aaagtcacca aatagtgtga 2900

 aatatattac ttaactgtcc gtaagcagta tattagtatt atcttgttca 2950

 ggaaaaggtt gaataatata tgccttgtgt aatattgaaa attgaaaagt 3000

 acaactaacg caaccaagtg tgctaaaaat gagcttgatt aaatcaacca 3050

 cctatttttg acatggaaat gaagcagggt ttcttttctt cactcaaatt 3100

 ttggcgaatc tcaaaattag atcctaagat gtgttcttat ttttataaca 3150

 tctttattga aattctattt ataatacaga atcttgtttt gaaaataacc 3200

 taattaatat attaaaattc caaattcatg gcatgcttaa attttaacta 3250

 aattttaaag ccattctgat tattgagttc cagttgaagt tagtggaaat 3300

 ctgaacattc tcctgtggaa ggcagagaaa tctaagctgt gtctgcccaa 3350

 tgaataatgg aaaatgccat gaattacctg gatgttcttt ttacgaggtg 3400

 acaagagttg gggacagaac tcccattaca actgaccaag tttctcttct 3450

 agatgatttt ttgaaagtta acattaatgc ctgctttttg gaaagtcaga 3500

 atcagaagat agtcttggaa gctgtttgga aaagacagtg gagatgaggt 3550

 cagttgtgtt ttttaagatg gcaattactt tggtagctgg gaaagcataa 3600

 agctcaaatg aaatgtatgc attcacattt agaaaagtga attgaagttt 3650

 caagttttaa agttcattgc aattaaactt ccaaagaaag ttctacagtg 3700

 tcctaagtgc taagtgctta ttacatttta ttaagctttt tggaatcttt 3750

 gtaccaaaat tttaaaaaag ggagtttttg atagttgtgt gtatgtgtgt 3800

 gtggggtggg gggatggtaa gagaaaagag agaaacactg aaaagaagga 3850

 aagatggtta aacattttcc cactcattct gaattaatta atttggagca 3900

 caaaattcaa agcatggaca tttagaagaa agatgtttgg cgtagcagag 3950

 ttaaatctca aataggctat taaaaaagtc tacaacatag cagatctgtt 4000

 ttgtggtttg gaatattaaa aaacttcatg taattttatt ttaaaatttc 4050

 atagctgtac ttcttgaata taaaaaatca tgccagtatt tttaaaggca 4100

 ttagagtcaa ctacacaaag caggcttgcc cagtacattt aaattttttg 4150

 gcacttgcca ttccaaaata ttatgcccca ccaaggctga gacagtgaat 4200

 ttgggctgct gtagcctatt tttttagatt gagaaatgtg tagctgcaaa 4250

 aataatcatg aaccaatctg gatgcctcat tatgtcaacc aggtccagat 4300

 gtgctataat ctgtttttac gtatgtaggc ccagtcgtca tcagatgctt 4350

 gcggcaaaag aaagctgtgt ttatatggaa gaaagtaagg tgcttggagt 4400

 ttacctggct tatttaatat gcttataacc tagttaaaga aaggaaaaga 4450

 aaacaaaaaa cgaatgaaaa taactgaatt tggaggctgg agtaatcaga 4500

 ttactgcttt aatcagaaac cctcattgtg tttctaccgg agagagaatg 4550

 tatttgctga caaccattaa agtcagaagt tttactccag gttattgcaa 4600

 taaagtataa tgtttattaa atgcttcatt tgtatgtcaa agctttgact 4650

 ctataagcaa attgcttttt tccaaaacaa aaagatgtct caggtttgtt 4700

 ttgtgaattt tctaaaagct ttcatgtccc agaacttagc ctttacctgt 4750

 gaagtgttac tacagcctta atattttcct agtagatcta tattagatca 4800

 aatagttgca tagcagtata tgttaatttg tgtgttttta gctgtgacac 4850

 aactgtgtga ttaaaaggta tactttagta gacatttata actcaaggat 4900

 accttcttat ttaatctttt cttatttttg tactttatca tgaatgcttt 4950

 tagtgtgtgc ataatagcta cagtgcatag ttgtagacaa agtacattct 5000

 ggggaaacaa catttatatg tagcctttac tgtttgatat accaaattaa 5050

 aaaaaaattg tatctcatta cttatactgg gacaccatta ccaaaataat 5100

 aaaaatcact ttcataatct tgaaaaaa 5128

<210> 595
<211> 543
<212> PRT
<213> Homo sapien

<400> 595
 Met Gly Thr Ser Leu Ser Pro Asn Asp Pro Trp Pro Leu Asn Pro
   1               5                  10                  15

 Leu Ser Ile Gln Gln Thr Thr Leu Leu Leu Leu Leu Ser Val Leu
                  20                  25                  30

 Ala Thr Val His Val Gly Gln Arg Leu Leu Arg Gln Arg Arg Arg
                  35                  40                  45

 Gln Leu Arg Ser Ala Pro Pro Gly Pro Phe Ala Trp Pro Leu Ile
                  50                  55                  60

 Gly Asn Ala Ala Ala Val Gly Gln Ala Ala His Leu Ser Phe Ala
                  65                  70                  75

 Arg Leu Ala Arg Arg Tyr Gly Asp Val Phe Gln Ile Arg Leu Gly
                  80                  85                  90

 Ser Cys Pro Ile Val Val Leu Asn Gly Glu Arg Ala Ile His Gln
                  95                 100                 105

 Ala Leu Val Gln Gln Gly Ser Ala Phe Ala Asp Arg Pro Ala Phe
                 110                 115                 120

 Ala Ser Phe Arg Val Val Ser Gly Gly Arg Ser Met Ala Phe Gly
                 125                 130                 135

 His Tyr Ser Glu His Trp Lys Val Gln Arg Arg Ala Ala His Ser
                 140                 145                 150

 Met Met Arg Asn Phe Phe Thr Arg Gln Pro Arg Ser Arg Gln Val
                 155                 160                 165

 Leu Glu Gly His Val Leu Ser Glu Ala Arg Glu Leu Val Ala Leu
                 170                 175                 180

 Leu Val Arg Gly Ser Ala Asp Gly Ala Phe Leu Asp Pro Arg Pro
                 185                 190                 195

 Leu Thr Val Val Ala Val Ala Asn Val Met Ser Ala Val Cys Phe
                 200                 205                 210

 Gly Cys Arg Tyr Ser His Asp Asp Pro Glu Phe Arg Glu Leu Leu
                 215                 220                 225

 Ser His Asn Glu Glu Phe Gly Arg Thr Val Gly Ala Gly Ser Leu
                 230                 235                 240

 Val Asp Val Met Pro Trp Leu Gln Tyr Phe Pro Asn Pro Val Arg
                 245                 250                 255

 Thr Val Phe Arg Glu Phe Glu Gln Leu Asn Arg Asn Phe Ser Asn
                 260                 265                 270

 Phe Ile Leu Asp Lys Phe Leu Arg His Cys Glu Ser Leu Arg Pro
                 275                 280                 285

 Gly Ala Ala Pro Arg Asp Met Met Asp Ala Phe Ile Leu Ser Ala
                 290                 295                 300

 Glu Lys Lys Ala Ala Gly Asp Ser His Gly Gly Gly Ala Arg Leu
                 305                 310                 315

 Asp Leu Glu Asn Val Pro Ala Thr Ile Thr Asp Ile Phe Gly Ala
                 320                 325                 330

 Ser Gln Asp Thr Leu Ser Thr Ala Leu Gln Trp Leu Leu Leu Leu
                 335                 340                 345

 Phe Thr Arg Tyr Pro Asp Val Gln Thr Arg Val Gln Ala Glu Leu
                 350                 355                 360

 Asp Gln Val Val Gly Arg Asp Arg Leu Pro Cys Met Gly Asp Gln
                 365                 370                 375

 Pro Asn Leu Pro Tyr Val Leu Ala Phe Leu Tyr Glu Ala Met Arg
                 380                 385                 390

 Phe Ser Ser Phe Val Pro Val Thr Ile Pro His Ala Thr Thr Ala
                 395                 400                 405

 Asn Thr Ser Val Leu Gly Tyr His Ile Pro Lys Asp Thr Val Val
                 410                 415                 420

 Phe Val Asn Gln Trp Ser Val Asn His Asp Pro Val Lys Trp Pro
                 425                 430                 435

 Asn Pro Glu Asn Phe Asp Pro Ala Arg Phe Leu Asp Lys Asp Gly
                 440                 445                 450

 Leu Ile Asn Lys Asp Leu Thr Ser Arg Val Met Ile Phe Ser Val
                 455                 460                 465

 Gly Lys Arg Arg Cys Ile Gly Glu Glu Leu Ser Lys Met Gln Leu
                 470                 475                 480

 Phe Leu Phe Ile Ser Ile Leu Ala His Gln Cys Asp Phe Arg Ala
                 485                 490                 495

 Asn Pro Asn Glu Pro Ala Lys Met Asn Phe Ser Tyr Gly Leu Thr
                 500                 505                 510

 Ile Lys Pro Lys Ser Phe Lys Val Asn Val Thr Leu Arg Glu Ser
                 515                 520                 525

 Met Glu Leu Leu Asp Ser Ala Val Gln Asn Leu Gln Ala Lys Glu
                 530                 535                 540

 Thr Cys Gln


<210> 596
<211> 12177
<212> DNA
<213> Homo sapien

<400> 596
 gagctcaatt aaccctcact aaagggagtc gactcgatct aaaaactaga 50

 tggcattatt gaggagttgg acaggcggtc ttaggaacaa cctcgtttta 100

 tactttttaa aaataggaat ttacttaaag gcaacttcca tctgctctca 150

 ttctggcaga ggtattgtga taaaggcttt caggaatgtc aacagctcag 200

 gattggcatt agctcataga taattcccgt ctactaaatt aaagtctatg 250

 agagattgat gcatgcacca gagtcttgaa ttattaggca aggatcttgc 300

 taaagctgga catgggaagg ttgctatgaa actcatttca aaggctgtgt 350

 aggccaactc acctctggga aaccaacgct tattattaaa ccaatgcaac 400

 tgctcaaaaa ctaaaactcc atcactatct aagttcccca tcatggtgtg 450

 tgaaatcatt tccagaaaac tcttcaaaag ataccgaata aaaggcatca 500

 caggccgggc acggtggctc atgcctgtaa tcccagcact ttgggaggcc 550

 caggctggtg gatcacctga ggtcaggagt ttgagaccag cctggccagc 600

 atggtgaaac cccatctcta ctagaaaaat acaaaaatta gccgggtgtg 650

 gtggtgcgca cctgtaatcc cagctacttg ggaggctgag ccaggagaac 700

 ctggcaggcg gaggttgcag tgagccgaga tcacgccatt gcactgcagc 750

 ccaggtgaca gagtgagact ccatctcaaa aaaaataaat aaataaaaat 800

 aaaaataaaa aaagccatca cgaaaagaca tttctttatc aggtcagcaa 850

 attgattgct ggtttcaatc tctcaagaag tcagattctc ttcagacact 900

 cctttgtgtt tctttacaat gtaatcagtc attccagggt cagctatgag 950

 gcacactccc ctggcctccc tcataagcaa tttaattgca aagggttagc 1000

 atactatttc ttctctgcta ttctcagaat tctcaattat gaaaacaaaa 1050

 acaataatta aaaagttctt ccagctgatt tttttttttt tttttgagac 1100

 agagtctcac ttaaactctg ctgcccaggc tgtagtgcag tggtgcaatc 1150

 tctgctcact gcaacctctg cctcccacgt tcaaccaatt ctgctgcctt 1200

 cccccctgat ccccgagtag ctgggattac aggtgtgcac caccacgtcc 1250

 ggctaacttt tgtattttta gtagatgggg tttcgccatg ttggccaggc 1300

 tggtctcgaa ctcctgacct caagtgatcc gcccgcttaa gcctcccaaa 1350

 gtgctgggat tacaggcgtg agccactgcg cctagcccca cgtgcatttt 1400

 ttttttttta agggaggcag gaaagaaggc atttgggcct cttatctgca 1450

 attttcttcc gtgtaaactt atgtgaagga tctggagtgg gacttggtgg 1500

 cttcaagccc tggctccact tcttgatggc tgcgcgacct gggttaagtc 1550

 acgcaacctc tctgaaccct agtttattca tctgtaaaca ggtcaataat 1600

 agcacgagat tgcagcgcga gtggagctca aagtgcaggg ttgtccctgg 1650

 tgaacctatc acttttatat ttatcctttg atgaagccag tacaattcct 1700

 acctggttaa ccagatacat cccacctctt ccctcgagtt cgcccttccc 1750

 cccgcctcgt gaagtccttg ttctcttagc tgtcttgaaa atcctatgca 1800

 tcagcatgta ggaaagggcg cgccaggcgg gggaagccac ccccgcccga 1850

 gcgcctccgg ttcccttata aagggagggc ccccttcgcg accgcaagcg 1900

 cgcccaggaa gaccacagag ccgccggtgc gcacggaggt ggcgatacgc 1950

 gcccgggctc ggcctgcggg tggtggccca agcgtccgcc tcgctggcct 2000

 ggcaggcgcg actgtgcgtg cgcagccgag ggtggtggcg gccggcaccc 2050

 cacgccaagg gtggtggtgg ccggcacccc accctcggcc gccgcctccg 2100

 cgtgtcaggt gccgtgagaa gcgcgggagg agcggccgca ggcagcgccc 2150

 agggatatga ctggagccga ctttccagaa gcggcgcacg caaagcccag 2200

 ctccgcacgc aaaggggagg cgacacgaga aacttcaacc cgataaagtt 2250

 cgccggagcg cggagattcg cctcctcctg ccactctccg ccccgctcgg 2300

 gtcccgcccc gctagctccc ccaggccccc ccagtcgccc cagcttggct 2350

 ccccgccctg cgccaacggc ttccatcgca gcctgggcgg ccccgcgccc 2400

 accagcgggc ggcgccacct ggagtggcct ctacgcggga aatctcaggg 2450

 ccagctgcgc cccaggagcc tttgtgtgcc caagcactgt cggggccccg 2500

 gggcggggga gcggctactt ttagggattc ctgatctcgc cgcaagaact 2550

 ggaaaaaatt tagcatgcca aagagcctcc actgaggtgg caatttgttt 2600

 gcgagaacct aagataaaat ttaaacaacc aaccaggggc gctgtgaggc 2650

 aaaccgctgc cactacactg gctttccggg aagcaagctc aagccgcgga 2700

 gagggaaggg aggtcgtgcg ctcggggcgg ggcgcgctcc caagtcgagc 2750

 gcagcggccg gggcaggttg taccgagcgt ggttctgggg acaccgtgcg 2800

 gccttgattg gaggtggctg tgatgaagcg cggttaccgc acaatggaaa 2850

 cgtgggcacc tccgctccca tgaaagcctg ctggtagagc tccgaggccg 2900

 gccggtgcgc ctggacggga gtccgggtca aagcggcctg gtgtgcggcg 2950

 cgccccgccc cccgcaggcc ccgccctgcc aggtcgcgct gccctccttc 3000

 tacccagtcc ttaaaacccg gaggagcggg atggcgcgct ttgactctgg 3050

 agtgggagtg ggagcgagcg cttctgcgac tccagttgtg agagccgcaa 3100

 gggcatggga attgacgcca ctcaccgacc cccagtctca atctcaacgc 3150

 tgtgaggaaa cctcgacttt gccaggtccc caagggcagc ggggctcggc 3200

 gagcgaggca cccttctccg tccccatccc aatccaagcg ctcctggcac 3250

 tgacgacgcc aagagactcg agtgggagtt aaagcttcca gtgagggcag 3300

 caggtgtcca ggccgggcct gcgggttcct gttgacgtct tgccctaggc 3350

 aaaggtccca gttccttctc ggagccggct gtcccgcgcc actggaaacc 3400

 gcacctcccc gcaggtcagt ctgtctgccg aggcgctgcc cggcgacctc 3450

 ttcagatgga ttattacagg tagcgggtgg cgtggtaggt actttaaagg 3500

 aaatcaagcg ccaccgcctc gatgcccgca gcgttgtccc caaattgcag 3550

 gaaccgttac gcgccttgcg gggaggggaa gggtttggcg ctgggttaca 3600

 gcgaggtgga aacacgcccc ttctcttctc caagggagag tgggttgggg 3650

 atgggaaggg gcgtcttcgg ccatttctcc agagagtcag ctccgacctc 3700

 tccacccaac ggcactcagt ccccagaggc tggggtaggg gcgtggggcg 3750

 cccgctcctg tctctgcacc cctgagtgtc acgccttctc ctttctgtcc 3800

 ccagcatggg caccagcctc agcccgaacg acccttggcc gctaaacccg 3850

 ctgtccatcc agcagaccac gctcctgcta ctcctgtcgg tgctggccac 3900

 tgtgcatgtg ggccagcggc tgctgaggca acggaggcgg cagctccggt 3950

 ccgcgccccc gggcccgttt gcgtggccac tgatcggaaa cgcggcggcg 4000

 gtgggccagg cggctcacct ctcgttcgct cgcctggcgc ggcgctacgg 4050

 cgacgttttc cagatccgcc tgggcagctg ccccatagtg gtgctgaatg 4100

 gcgagcgcgc catccaccag gccctggtgc agcagggctc ggccttcgcc 4150

 gaccggccgg ccttcgcctc cttccgtgtg gtgtccggcg gccgcagcat 4200

 ggctttcggc cactactcgg agcactggaa ggtgcagcgg cgcgcagccc 4250

 acagcatgat gcgcaacttc ttcacgcgcc agccgcgcag ccgccaagtc 4300

 ctcgagggcc acgtgctgag cgaggcgcgc gagctggtgg cgctgctggt 4350

 gcgcggcagc gcggacggcg ccttcctcga cccgaggccg ctgaccgtcg 4400

 tggccgtggc caacgtcatg agtgccgtgt gtttcggctg ccgctacagc 4450

 cacgacgacc ccgagttccg tgagctgctc agccacaacg aagagttcgg 4500

 gcgcacggtg ggcgcgggca gcctggtgga cgtgatgccc tggctgcagt 4550

 acttccccaa cccggtgcgc accgttttcc gcgaattcga gcagctcaac 4600

 cgcaacttca gcaacttcat cctggacaag ttcttgaggc actgcgaaag 4650

 ccttcggccc ggggccgccc cccgcgacat gatggacgcc tttatcctct 4700

 ctgcggaaaa gaaggcggcc ggggactcgc acggtggtgg cgcgcggctg 4750

 gatttggaga acgtaccggc cactatcact gacatcttcg gcgccagcca 4800

 ggacaccctg tccaccgcgc tgcagtggct gctcctcctc ttcaccaggt 4850

 aaagcctctg ggaggcgtgg gccaggtctt ttctcctctg aaaaaggcgg 4900

 agtagagaca gaatatgctg agtttgcaag cagggccccg ggtttggggt 4950

 ttcgctccag gtccccaccc ctcaaaacca agatcgcgtc ggtaaaggga 5000

 ctcacagtga gggctgcgac acgcacgcgc cccacccagc ggtgccccga 5050

 cccctccggt ctcctatctt gtctctatcg tcccctcccc tgcttgcgag 5100

 tgagaacaca tttgcaaaga cccctccacc ccccgggaaa aacaagagtt 5150

 tttaaatgct tggagatgag ccctgatatc tctctccctg gcgcattaca 5200

 atcagaactg gaatagttcc gaaagaaaag gtaatgtcat aaatatgtta 5250

 aacacagcag cctctcctag gctagtcctc ggcgtgcatc cgaggccgcc 5300

 cagccctggc gctaaaagcg ggccgcccgt cagggctttg ttccaggcca 5350

 aggaagccca tggaggccgg gccagccgac aggtaacccg cacagaaact 5400

 ttcagaaggc ggccacaact agcgggcagc gctaggttta taaaacctcc 5450

 gcgctaggag tttgagaaat gccggggtag aagacaagaa gcagtcactt 5500

 ttacgaaagc agagtagcat tcagaaaggc agatgggata tccaggaggc 5550

 gcctgcagac gtttctggcc cctgcgcttg gctcagttag cggaccccct 5600

 gatgcccacg ttggtctcta ctaagcacgg attcaacagg tccctggtgt 5650

 cgggttgcca gatttggcaa aagaaaagta agttttacac gggaatactc 5700

 acactaaaag attagccctt gttgatctga aatccatatt taactgggcg 5750

 gcctgtagta tttactgtgg aaacactatc cctaggggca aatgtttcgc 5800

 aaggcaaatt ttgattgccg aagagaccag aaatcctggt tttgtgtcat 5850

 ttcttggagc acaagtgagc agttggagat gctgaatctg caggcgccac 5900

 agaaaggtgt ttggaaggca gagaatgact ctttccttat taaaatccac 5950

 tgcaatctat atttccttag atactgtaca gctaccttca caaattaaaa 6000

 gtttctgtat acttaaaatg gctttttagt attaaaatca tagaaacacc 6050

 catggtgggt gagggagagg cagaaatcga ataaagaaaa gtcaaccaga 6100

 gatcagggaa aaggaaatcc cggaataggt tccataggtt tttgtgcatc 6150

 cgcagatagg cattttaact tttgaaacgg cctttgtttt tcattagaac 6200

 cacaatagtt ctccgagtac tccaattagg cggcaaaaag aaataaaaca 6250

 atttggaggt cactttcaat tcaatatgct gatacttttt tttccttttt 6300

 agtgaaaaga cgtatgacag ggcttggcaa attacacgat ctgtttttgt 6350

 atatacgttt tattgacgca gtcatgccca ttcatttata cattgtcgat 6400

 ggctgcgttc actctacaac acaaggcaga gcagagtagt gcaacaaaga 6450

 gggtttggtc cacaaagtct aaaatagata ctctctggct ctccccacca 6500

 tacatgtttc tatgaaaaaa gttggcagac tcctgcaata taatgttgaa 6550

 gaagcgattc taaaaataac tccacttcat cacatacgtg tatacatttt 6600

 ttttcggagt tgcaaacaat cagttacttg ttttttgact tctaacactt 6650

 tgactcaagg tagtggacat ttctaatctt ttaatattta ttttggtaat 6700

 ttttgatggc tatatagtat tttgctatga taatgtatag ttatatataa 6750

 tcatttattg aactttaatg ttggtcattg gccttgattg catttttaaa 6800

 atttttattt taattttatg tatttactta ccttagagac agggtctcac 6850

 taccttaccc aggctggtcc caaactcctg ggctcaagca gttctcccgc 6900

 cgctgtctgg caggtagctg gggctacagg cgtgtaccac catgcctggc 6950

 taatttttag aattttaggt cctgttgtgg ttacatattt ttgtatctct 7000

 taaattattt tctgaaaata catttctagg catggattac tgggtttaaa 7050

 atgaggcggg aagaggttac cttcatgtct cttgcctcgt attaagattt 7100

 tgttttttaa aaagattgta tcagtttgta tcatcaacag tgaataagta 7150

 ctacagtttg taccataatt ttatgaacat tgggtatttg ctttcaaatt 7200

 taaaaaatac agtatgtagc tttatccatc aggacaccaa ttatctttgt 7250

 ataaaatgag aacagcatgt ctgttggaat tgtccaggga aatgagggag 7300

 aaaaaaaatt tactttcaca ttgtaacttt cgtgggccct gggtgctttt 7350

 gcctttgtag attccttata ctataaaaaa attaaaaatt aaatttcatg 7400

 actaccctga tataaagatg aatgcattaa aatgatgtat gaaaatattt 7450

 tcttctacct aaaagtgagt ttttttaggt ctgaagattg taaaagacgt 7500

 aaaaatattt tcatgggccc ctaaaaagtg ttgtgagccc taggcactgt 7550

 cctgcggtac ccaatggaaa agtcagcctt atctactatt gtgctttttg 7600

 aggctgggaa aacttaagag ttttttgact tataatggga aagacagcat 7650

 tagtcatgca aggcctatta caggaaatat aattcttaaa gtccatcttg 7700

 taatttagtg agaaattagg aagctgtttt agattttttt cccagaaata 7750

 ttaatttagt cactgagcta gatagcctat ttaagaaaaa gtggaattaa 7800

 aataaattat aatgtgcttt ctagatgaaa taagaatttt gctcacttgc 7850

 ttttctctct ccacattaaa caccaaacag gtatcctgat gtgcagactc 7900

 gagtgcaggc agaattggat caggtcgtgg ggagggaccg tctgccttgt 7950

 atgggtgacc agcccaacct gccctatgtc ctggccttcc tttatgaagc 8000

 catgcgcttc tccagctttg tgcctgtcac tattcctcat gccaccactg 8050

 ccaacacctc tgtcttgggc taccacattc ccaaggacac tgtggttttt 8100

 gtcaaccagt ggtctgtgaa tcatgaccca ctgaagtggc ctaacccgga 8150

 gaactttgat ccagctcgat tcttggacaa ggacggcctc atcaacaagg 8200

 acctgaccag cagagtgatg attttttcag tgggcaaaag gcggtgcatt 8250

 ggcgaagaac tttctaagat gcagcttttt ctcttcatct ccatcctggc 8300

 tcaccagtgc gatttcaggg ccaacccaaa tgagcctgcg aaaatgaatt 8350

 tcagttatgg tctaaccatt aaacccaagt catttaaagt caatgtcact 8400

 ctcagagagt ccatggagct ccttgatagt gctgtccaaa atttacaagc 8450

 caaggaaact tgccaataag aagcaagagg caagctgaaa ttttagaaat 8500

 attcacatct tcggagatga ggagtaaaat tcagtttttt tccagttcct 8550

 cttttgtgct gcttctcaat tagcgtttaa ggtgagcata aatcaactgt 8600

 ccatcaggtg aggtgtgctc catacccagc ggttcttcat gagtagtggg 8650

 ctatgcagga gcttctggga gatttttttg agtcaaagac ttaaagggcc 8700

 caatgaatta ttatatacat actgcatctt ggttatttct gaaggtagca 8750

 ttctttggag ttaaaatgca catatagaca catacaccca aacacttaca 8800

 ccaaactact gaatgaagaa gtattttggt aaccaggcca tttttggtgg 8850

 gaatccaaga ttggtctccc atatgcagaa atagacaaaa agtatattaa 8900

 acaaagtttc agagtatatt gttgaagaga cagagacaag taatttcagt 8950

 gtaaagtgtg tgattgaagg tgataaggga aaagataaag accagaaatt 9000

 cccttttcac cttttcagga aaataactta gactctagta tttatgggtg 9050

 gatttatcct tttgccttct ggtatacttc cttactttta aggataaatc 9100

 ataaagtcag ttgctcaaaa agaaatcaat agttgaatta gtgagtatag 9150

 tggggttcca tgatttatca tgaattttaa agtatgcatt attaaattgt 9200

 aaaactccaa ggtgatgttg tacctctttt gcttgccaaa gtacagaatt 9250

 tgaattatca gcaaagaaaa aaaaaaaagc cagccaagct ttaaattatg 9300

 tgaccataat gtactgattt cagtaagtct cataggttaa aaaaaaaagt 9350

 caccaaatag tgtgaaatat attacttaac tgtccgtaag cagtatatta 9400

 gtattatctt gttcaggaaa aggttgaata atatatgcct tgtgtaatat 9450

 tgaaaattga aaagtacaac taacgcaacc aagtgtgcta aaaatgagct 9500

 tgattaaatc aaccacctat ttttgacatg gaaatgaagc agggtttctt 9550

 ttcttcactc aaattttggc gaatctcaaa attagatcct aagatgtgtt 9600

 cttattttta taacatcttt attgaaattc tatttataat acagaatctt 9650

 gttttgaaaa taacctaatt aatatattaa aattccaaat tcatggcatg 9700

 cttaaatttt aactaaattt taaagccatt ctgattattg agttccagtt 9750

 gaagttagtg gaaatctgaa cattctcctg tggaaggcag agaaatctaa 9800

 gctgtgtctg cccaatgaat aatggaaaat gccatgaatt acctggatgt 9850

 tctttttacg aggtgacaag agttggggac agaactccca ttacaactga 9900

 ccaagtttct cttctagatg attttttgaa agttaacatt aatgcctgct 9950

 ttttggaaag tcagaatcag aagatagtct tggaagctgt ttggaaaaga 10000

 cagtggagat gaggtcagtt gtgtttttta agatggcaat tactttggta 10050

 gctgggaaag cataaagctc aaatgaaatg tatgcattca catttagaaa 10100

 agtgaattga agtttcaagt tttaaagttc attgcaatta aacttccaaa 10150

 gaaagttcta cagtgtccta agtgctaagt gcttattaca ttttattaag 10200

 ctttttggaa tctttgtacc aaaattttaa aaaagggagt ttttgatagt 10250

 tgtgtgtatg tgtgtgtggg gtggggggat ggtaagagaa aagagagaaa 10300

 cactgaaaag aaggaaagat ggttaaacat tttcccactc attctgaatt 10350

 aattaatttg gagcacaaaa ttcaaagcat ggacatttag aagaaagatg 10400

 tttggcgtag cagagttaaa tctcaaatag gctattaaaa aagtctacaa 10450

 catagcagat ctgttttgtg gtttggaata ttaaaaaact tcatgtaatt 10500

 ttattttaaa atttcatagc tgtacttctt gaatataaaa aatcatgcca 10550

 gtatttttaa aggcattaga gtcaactaca caaagcaggc ttgcccagta 10600

 catttaaatt ttttggcact tgccattcca aaatattatg ccccaccaag 10650

 gctgagacag tgaatttggg ctgctgtagc ctattttttt agattgagaa 10700

 atgtgtagct gcaaaaataa tcatgaacca atctggatgc ctcattatgt 10750

 caaccaggtc cagatgtgct ataatctgtt tttacgtatg taggcccagt 10800

 cgtcatcaga tgcttgcggc aaaagaaagc tgtgtttata tggaagaaag 10850

 taaggtgctt ggagtttacc tggcttattt aatatgctta taacctagtt 10900

 aaagaaagga aaagaaaaca aaaaacgaat gaaaataact gaatttggag 10950

 gctggagtaa tcagattact gctttaatca gaaaccctca ttgtgtttct 11000

 accggagaga gaatgtattt gctgacaacc attaaagtca gaagttttac 11050

 tccaggttat tgcaataaag tataatgttt attaaatgct tcatttgtat 11100

 gtcaaagctt tgactctata agcaaattgc ttttttccaa aacaaaaaga 11150

 tgtctcaggt ttgttttgtg aattttctaa aagctttcat gtcccagaac 11200

 ttagccttta cctgtgaagt gttactacag ccttaatatt ttcctagtag 11250

 atctatatta gatcaaatag ttgcatagca gtatatgtta atttgtgtgt 11300

 ttttagctgt gacacaactg tgtgattaaa aggtatactt tagtagacat 11350

 ttataactca aggatacctt cttatttaat cttttcttat ttttgtactt 11400

 tatcatgaat gcttttagtg tgtgcataat agctacagtg catagttgta 11450

 gacaaagtac attctgggga aacaacattt atatgtagcc tttactgttt 11500

 gatataccaa attaaaaaaa aattgtatct cattacttat actgggacac 11550

 cattaccaaa ataataaaaa tcactttcat aatcttgtta tgaagtttta 11600

 tgttgtagca aatatagtct aatgtatcac tttatttcaa ctattactat 11650

 ggattattca attaaaatat tgcactgtaa acattttatt tgtccattct 11700

 acatttcagg ccgaggccac atgctttttt ttcccgtagg ttttcatcaa 11750

 ccaaatttct aatctctata tttttgaatt tctaagaacc aacacggagg 11800

 ttacatttca atcaaacaat caagccaaat gagaattaat ttgcaatgtt 11850

 gaaagattga atagattgcg actttaagtt gctgatcgat ttctgcttca 11900

 tctaaagaat gcagtacaca tttttcttcc tcagcctcat accagtcctt 11950

 tctctgagta ttttcttctt tcattttttt aaaggtacat gtgcctcaat 12000

 tagtgcaatt aatgtccaat aaaataagat gggtacaagt attctgtcat 12050

 gtactatgtg gaaatgtttt attgccaatc tttttacttg gtaaaaatac 12100

 ttgacttcac agggcctagg tcatgactct ccaggccttc actgtgccac 12150

 actcacagat gacagggctt gcggtac 12177

<210> 597
<211> 4205
<212> DNA
<213> Homo sapien

<400> 597
 aataagaatt agttgaagaa atgaatagga agggagtccc cttagatgga 50

 ggaagggact ttctcaaaag gcctcatgga aggagaatgg cattgaggct 100

 ggcttacaag aagtgtgtct tttataaaaa gaaggaaggg cagggcttcc 150

 aggtgaaagg catagcacaa gccaaggcca aaagacgggt aactgctagt 200

 tgttaagggc agtggctgaa tcgctatacc cctagcagtt ctacacctag 250

 gggcctgcgg gccgctgggt ctgcgaagct tgcaaggcaa ctggcccgcc 300

 cccgctctgc gcctgtctct cggccacgcc taatgctgca ggatgacgcg 350

 cacctctaga acccgccccg gaggggaggg acgcagggaa gagtcgcacg 400

 gacgcactcg cgctgcggcc agcgcccggg cctgcgggcc cgggcggcgg 450

 ctgtgttgcg cagtcttcat gggttcccga cgaggaggtc tctgtggctg 500

 cggcggcggc tgctaactgc gccacctgct gcagcctgtc cccgccgctc 550

 tgaagcggcc gcgtcgaagc cgaaatgccg ccaccccgga ccggccgagg 600

 ccttctctgg ctgggtctgg ttctgagctc cgtctgcgtc gccctcggat 650

 ccgaaacgca ggccaactcg accacagatg ctctgaacgt tcttctcatc 700

 atcgtggatg acctgcgccc ctccctgggc tgttatgggg ataagctggt 750

 gaggtcccca aatattgacc aactggcatc ccacagcctc ctcttccaga 800

 atgcctttgc gcagcaagca gtgtgcgccc cgagccgcgt ttctttcctc 850

 actggcagga gacctgacac cacccgcctg tacgacttca actcctactg 900

 gagggtgcac gctggaaact tctccaccat cccccagtac ttcaaggaga 950

 atggctatgt gaccatgtcg gtgggaaaag tctttcaccc tgggatatct 1000

 tctaaccata ccgatgattc tccgtatagc tggtcttttc caccttatca 1050

 tccttcctct gagaagtatg aaaacactaa gacatgtcga gggccagatg 1100

 gagaactcca tgccaacctg ctttgccctg tggatgtgct ggatgttccc 1150

 gagggcacct tgcctgacaa acagagcact gagcaagcca tacagttgtt 1200

 ggaaaagatg aaaacgtcag ccagtccttt cttcctggcc gttgggtatc 1250

 ataagccaca catccccttc agatacccca aggaatttca gaagttgtat 1300

 cccttggaga acatcaccct ggcccccgat cccgaggtcc ctgatggcct 1350

 accccctgtg gcctacaacc cctggatgga catcaggcaa cgggaagacg 1400

 tccaagcctt aaacatcagt gtgccgtatg gtccaattcc tgtggacttt 1450

 cagcggaaaa tccgccagag ctactttgcc tctgtgtcat atttggatac 1500

 acaggtcggc cgcctcttga gtgctttgga cgatcttcag ctggccaaca 1550

 gcaccatcat tgcatttacc tcggatcatg ggtgggctct aggtgaacat 1600

 ggagaatggg ccaaatacag caattttgat gttgctaccc atgttcccct 1650

 gatattctat gttcctggaa ggacggcttc acttccggag gcaggcgaga 1700

 agcttttccc ttacctcgac ccttttgatt ccgcctcaca gttgatggag 1750

 ccaggcaggc aatccatgga ccttgtggaa cttgtgtctc tttttcccac 1800

 gctggctgga cttgcaggac tgcaggttcc acctcgctgc cccgttcctt 1850

 catttcacgt tgagctgtgc agagaaggca agaaccttct gaagcatttt 1900

 cgattccgtg acttggaaga ggatccgtac ctccctggta atccccgtga 1950

 actgattgcc tatagccagt atccccggcc ttcagacatc cctcagtgga 2000

 attctgacaa gccgagttta aaagatataa agatcatggg ctattccata 2050

 cgcaccatag actataggta tactgtgtgg gttggcttca atcctgatga 2100

 atttctagct aacttttctg acatccatgc aggggaactg tattttgtgg 2150

 attctgaccc attgcaggat cacaatatgt ataatgattc ccaaggtgga 2200

 gatcttttcc agttgttgat gccttgagtt ttgccaacca tggatggcaa 2250

 atgtgatgtg ctcccttcca gctggtgaga ggaggagtta gagctggtcg 2300

 ttttgtgatt acccataata ttggaagcag cctgagggct agttaatcca 2350

 aacatgcatc aacaatttgg cctgagaata tgtaacagcc aaaccttttc 2400

 gtttagtctt tattaaaatt tataattggt aattggacca gttttttttt 2450

 taatttccct ctttttaaaa cagttacggc ttatttactg aataaataca 2500

 aagcaaacaa actcaagtta tgtcatacct ttggatacga agaccataca 2550

 taataaccaa acataacatt atacacaaag aatactttca ttatttgtgg 2600

 aatttagtgc atttcaaaaa gtaatcatat atcaaactag gcaccacact 2650

 aagttcctga ttattttgtt tataatttaa taatatatct tatgagccct 2700

 atatattcaa aatattatgt taacatgtaa tccatgtttc tttttcaaat 2750

 ctaaagttaa aaaaaaatag cagaagccag tgtcttaaag tctatctttt 2800

 gtttctaaga ccatgggatt tcataatctc aagataaaat atgtatgaag 2850

 taattaatgt agaattttta caccaaataa taaataatgc ttaataaact 2900

 agagatatga gatgtgtagg aaatttggtt aaactttttt cagatacttt 2950

 ctggcccaaa taataatttg ttagcaaata atatgaccct tgaactcaat 3000

 ggccatctat taaaagactg ttgttcacac tggaaaacat ttaaagatgt 3050

 gactatatcc atgggtggat tgaatcactc aaaatatatt agtatccttc 3100

 tttagggatg gttggttaca gacatgtatt tattcaggag gcagaaaata 3150

 ttccatttta attgcttatt aaagaaaaca ttaaattcta aattattttg 3200

 aggactgtga agacttttca ttagtgtaat attaggtcat tgtcaatctc 3250

 ccagaatgta gttctatatt ctctaaatat gaaagtatcc agaaaggcca 3300

 gtggtagtaa aaagcttagt gtatataatc tcaaaaggga tggaatattt 3350

 acaactcata tttataacat gttgaatctt ctcagttatc agtagtcatc 3400

 agaagtgtca atagctttct aaataaatat taaatatcta ctgtcctgta 3450

 gtgaaggagt aatttttagt aattttctct ttacaaagtc tccagtgttt 3500

 ccaggtaaat atttgtgaaa caaaatacag caaactacat tgttacttca 3550

 gtgtattgtt gccaaaaatg acaagatatt atattaaaat cagtaaattt 3600

 tagacagatt ttaaaaatta attagcctac aatagaggtt atatggtaac 3650

 acggtgatct tctaagcagt taagtgactg actgttctgg caacaacgac 3700

 ttctccgtga ctgaagggcc ctgttcattt cctgatcctg aagctcgtct 3750

 ctcttttgag cctccgcttg ctttggtcga tggtttccct cagctttttc 3800

 tttgctgttc ttcatcctcg ttgttgctgt catcatgttc actgtggctt 3850

 ttacaataca gcctgtaaat tccttatgac atagttcagt gcatttggct 3900

 ttatcgcctg ctccacagtt ctttaccttt acttggctta gagaaactgt 3950

 atctttgttg cttcatataa cctttcccca accccactaa gctggacata 4000

 acttattagt ggtcctcccg tcactttatt tgtagaaatc tctctttcac 4050

 atgagcaggg gttctttcat gtggtttagc tgacagcaga actagtgatt 4100

 ctagacattt tgcatggccc tcattcagtg gctcacaaaa catgagggag 4150

 catcagaact acttgagggg cttgtttaaa acccagtgcg ttagaagtcc 4200

 ggatg 4205

<210> 598
<211> 550
<212> PRT
<213> Homo sapien

<400> 598
 Met Pro Pro Pro Arg Thr Gly Arg Gly Leu Leu Trp Leu Gly Leu
   1               5                  10                  15

 Val Leu Ser Ser Val Cys Val Ala Leu Gly Ser Glu Thr Gln Ala
                  20                  25                  30

 Asn Ser Thr Thr Asp Ala Leu Asn Val Leu Leu Ile Ile Val Asp
                  35                  40                  45

 Asp Leu Arg Pro Ser Leu Gly Cys Tyr Gly Asp Lys Leu Val Arg
                  50                  55                  60

 Ser Pro Asn Ile Asp Gln Leu Ala Ser His Ser Leu Leu Phe Gln
                  65                  70                  75

 Asn Ala Phe Ala Gln Gln Ala Val Cys Ala Pro Ser Arg Val Ser
                  80                  85                  90

 Phe Leu Thr Gly Arg Arg Pro Asp Thr Thr Arg Leu Tyr Asp Phe
                  95                 100                 105

 Asn Ser Tyr Trp Arg Val His Ala Gly Asn Phe Ser Thr Ile Pro
                 110                 115                 120

 Gln Tyr Phe Lys Glu Asn Gly Tyr Val Thr Met Ser Val Gly Lys
                 125                 130                 135

 Val Phe His Pro Gly Ile Ser Ser Asn His Thr Asp Asp Ser Pro
                 140                 145                 150

 Tyr Ser Trp Ser Phe Pro Pro Tyr His Pro Ser Ser Glu Lys Tyr
                 155                 160                 165

 Glu Asn Thr Lys Thr Cys Arg Gly Pro Asp Gly Glu Leu His Ala
                 170                 175                 180

 Asn Leu Leu Cys Pro Val Asp Val Leu Asp Val Pro Glu Gly Thr
                 185                 190                 195

 Leu Pro Asp Lys Gln Ser Thr Glu Gln Ala Ile Gln Leu Leu Glu
                 200                 205                 210

 Lys Met Lys Thr Ser Ala Ser Pro Phe Phe Leu Ala Val Gly Tyr
                 215                 220                 225

 His Lys Pro His Ile Pro Phe Arg Tyr Pro Lys Glu Phe Gln Lys
                 230                 235                 240

 Leu Tyr Pro Leu Glu Asn Ile Thr Leu Ala Pro Asp Pro Glu Val
                 245                 250                 255

 Pro Asp Gly Leu Pro Pro Val Ala Tyr Asn Pro Trp Met Asp Ile
                 260                 265                 270

 Arg Gln Arg Glu Asp Val Gln Ala Leu Asn Ile Ser Val Pro Tyr
                 275                 280                 285

 Gly Pro Ile Pro Val Asp Phe Gln Arg Lys Ile Arg Gln Ser Tyr
                 290                 295                 300

 Phe Ala Ser Val Ser Tyr Leu Asp Thr Gln Val Gly Arg Leu Leu
                 305                 310                 315

 Ser Ala Leu Asp Asp Leu Gln Leu Ala Asn Ser Thr Ile Ile Ala
                 320                 325                 330

 Phe Thr Ser Asp His Gly Trp Ala Leu Gly Glu His Gly Glu Trp
                 335                 340                 345

 Ala Lys Tyr Ser Asn Phe Asp Val Ala Thr His Val Pro Leu Ile
                 350                 355                 360

 Phe Tyr Val Pro Gly Arg Thr Ala Ser Leu Pro Glu Ala Gly Glu
                 365                 370                 375

 Lys Leu Phe Pro Tyr Leu Asp Pro Phe Asp Ser Ala Ser Gln Leu
                 380                 385                 390

 Met Glu Pro Gly Arg Gln Ser Met Asp Leu Val Glu Leu Val Ser
                 395                 400                 405

 Leu Phe Pro Thr Leu Ala Gly Leu Ala Gly Leu Gln Val Pro Pro
                 410                 415                 420

 Arg Cys Pro Val Pro Ser Phe His Val Glu Leu Cys Arg Glu Gly
                 425                 430                 435

 Lys Asn Leu Leu Lys His Phe Arg Phe Arg Asp Leu Glu Glu Asp
                 440                 445                 450

 Pro Tyr Leu Pro Gly Asn Pro Arg Glu Leu Ile Ala Tyr Ser Gln
                 455                 460                 465

 Tyr Pro Arg Pro Ser Asp Ile Pro Gln Trp Asn Ser Asp Lys Pro
                 470                 475                 480

 Ser Leu Lys Asp Ile Lys Ile Met Gly Tyr Ser Ile Arg Thr Ile
                 485                 490                 495

 Asp Tyr Arg Tyr Thr Val Trp Val Gly Phe Asn Pro Asp Glu Phe
                 500                 505                 510

 Leu Ala Asn Phe Ser Asp Ile His Ala Gly Glu Leu Tyr Phe Val
                 515                 520                 525

 Asp Ser Asp Pro Leu Gln Asp His Asn Met Tyr Asn Asp Ser Gln
                 530                 535                 540

 Gly Gly Asp Leu Phe Gln Leu Leu Met Pro
                 545                 550

<210> 599
<211> 4425
<212> DNA
<213> Homo sapien

<400> 599
 gcgcgcgtgg ggctccattc cgcggtgctg ggtctccgtg ccggggtggg 50

 tgctcgtgtg tgcgcttctc ctccccatcc cccttccccc aagaataaaa 100

 gaagaaccgg gaggcgtgct cagaaaataa ataaataacc accacacacg 150

 cgcagcccgg agcgagtcgg cggggctggc ggcagcggcg gaggaggagt 200

 gaaggcggcg gcggcggagg agggacgcgc ggaaaaggca gcaactttaa 250

 agccagctca gagcctagac ctccagccga gcggtttgca gcgcggcggc 300

 ggcggcggcg gcggcggcgg cggcgttgag tgtctggccc gccggtccgg 350

 tcggggtgtg cagtcggacg gacgagcagc gcgtcgctgt cctccggcag 400

 ctggagatgt ccgagcccaa ggcaattgat cccaagttgt cgacgaccga 450

 cagggtggtg aaagctgttc catttcctcc aagtcaccgg cttacagcaa 500

 aagaagtgtt tgataatgat ggaaaacctc gtgtggatat cttaaaggcg 550

 catcttatga aggagggaag gctggaagag agtgttgcat tgagaataat 600

 aacagagggt gcatcaattc ttcgacagga aaaaaatttg ctggatattg 650

 atgcgccagt cactgtttgt ggggacattc atggacaatt ctttgatttg 700

 atgaagctct ttgaagtcgg gggatctcct gccaacactc gctacctctt 750

 cttaggggac tatgttgaca gagggtactt cagtattgaa tgtgtgctgt 800

 atttgtgggc cttgaaaatt ctctacccca aaacactgtt tttacttcgt 850

 ggaaatcatg aatgtagaca tctaacagag tatttcacat ttaaacaaga 900

 atgtaaaata aagtattcag aacgcgtata tgatgcctgt atggatgcct 950

 ttgactgcct tcccctggct gccctgatga accaacagtt cctgtgtgtg 1000

 catggtggtt tgtctccaga gattaacact ttagatgata tcagaaaatt 1050

 agaccgattc aaagaaccac ctgcatatgg acctatgtgt gatatcctgt 1100

 ggtcagaccc cctggaagat tttggaaatg agaagactca ggaacatttc 1150

 actcacaaca cagtcagggg gtgttcatac ttctacagtt acccggctgt 1200

 atgtgaattc ttacagcaca ataacttgtt atctatactc cgagcccacg 1250

 aagcccaaga tgcagggtac cgcatgtaca ggaaaagcca aacaacaggc 1300

 ttcccttctc taattacaat tttttcagca ccaaattact tagatgtata 1350

 caataacaaa gctgcagtat tgaagtatga gaacaatgtt atgaatatca 1400

 ggcaattcaa ctgttctcct catccatact ggcttccaaa tttcatggat 1450

 gtttttactt ggtcccttcc atttgttggg gaaaaagtga ctgagatgct 1500

 ggtaaatgtc ctcaacatct gctcagatga tgaactaggg tcagaagaag 1550

 atggatttga tggtgcaaca gctgcagccc ggaaagaggt gataaggaac 1600

 aagatccgag caataggcaa aatggccaga gtgttctcag tgctcagaga 1650

 agagagtgag agtgtgctga cgctgaaagg cttgacccca actggcatgc 1700

 tccccagcgg agtactttct ggagggaagc aaaccctgca aagcgctact 1750

 gttgaggcta ttgaggctga tgaagctatc aaaggatttt caccacaaca 1800

 taagatcact agcttcgagg aagccaaggg cttagaccga attaatgaga 1850

 ggatgccgcc tcgcagagat gccatgccct ctgacgccaa ccttaactcc 1900

 atcaacaagg ctctcacctc agagactaac ggcacggaca gcaatggcag 1950

 taatagcagc aatattcagt gaccacttcc tgttcacttt tttttttttt 2000

 tttttttttt tttgagctgc ggggcatgat ggggattgct gcatatcagc 2050

 agttggatgt tcttgcctct gacagtagct tatttgctct gggggccagg 2100

 aattggattc agtttacact atcattaaaa aagagggaga gagataataa 2150

 actatatttt ggtggggatg gtgattaaac acctcttttg ggtatgcctt 2200

 ttaaaaatgc ttatagagaa aaaaatttta aaaagaaagc taatgctagt 2250

 atatactgca atgttagggg aatgaacatg ttttcctact gcattgggga 2300

 cttctagata ggttaatgaa aggcctttta ttctgttact ggacatgaaa 2350

 actttgtcta atttcttact ctattgtacg tttacagtcg cagcactaaa 2400

 aatggatgac atcaaacatt tttaacaaaa tgatgtacaa actaaggact 2450

 atttattgat aatgttttgc tactcttgtc agacaatggc tataaactga 2500

 attaggcagt cttaaaaaaa aaaaaaaaac agaaaaagaa aaaaaagaac 2550

 gttgcaaatt tgttaaaatg ccaaaaagga cagtttaatt ttgtacagat 2600

 tatgcttacc tcaggtttct ttagtgtgct tgaatgccct tctttccata 2650

 taacacttat cttcttctta attcggcaat ggaatatctt ttaagtttta 2700

 aaaaaactgg aataattata tctatctttt ttgccgttta tatttagggg 2750

 tttttgttga taaaatcaag tcttggttgt ggcttgctga attaaatatt 2800

 tatgagtggt gcatttttaa gtatagtgaa caagacacca tattaagtac 2850

 agtgataaag catctatatt ctgtaaaaaa aaaaaaaatc tgcctatgca 2900

 tgttttttaa gaaaaaaaaa atggctgtat cggcctgtat gggactgtaa 2950

 tgcgcttagt ggtctgacat atactggaaa tgtatgtata ctggcgtact 3000

 ttatattctc taaaatgctt aatgcctttg aaattttgta atcaaaaaaa 3050

 agctttgaaa aaatctaaag gggagagtat tctttaaagt ttttaacata 3100

 agcttgtcaa tgcacatgta gatggttagc atgtttagca aaccttgtga 3150

 aattataata agtttgtagt tacatgtgaa actctaaatg catggcaact 3200

 gttaatgtca taacagttta gttattttgt tctgttctgt catgtgccac 3250

 aaaatatgta cttttttcac ttttttccct ttgtatatca gttacgggtt 3300

 acaactggtt cattctgaaa acaacaacaa caaaagtcca ttcatatttt 3350

 ttaacaattg tataagtgcc caagtaattc actacagcct aaagccttgc 3400

 ctttgtaatt tgacttctga catgttggca atcaaagcat gcacttgtaa 3450

 caatgaaaaa gaaaaagcat tttatattac tactcaataa aatgtgcatg 3500

 aacttacaga attctcatcc ttccactgag tccgctgaag ggatttatgt 3550

 gcacaaccac catgtgtctt ctaggtgctg gcccaccacc acacatcaca 3600

 ggctgatttc cacaggcttc ttcctagggg cctcgtgatc tgaggggtgg 3650

 tgcctacttc cactgtaaga aagaatcttg gtggatttgt gtctcaaatc 3700

 agataagaga agcctgttta aagagcagat gccatcttct ggcttcctca 3750

 aggagccagt taaaaaacca gagcattcct ttttattgaa aaataaaatt 3800

 aatttgttat caggttgttt cagttgtatt ggatgcccta tctatctgct 3850

 aaagcaaaaa gtactaggct actaagtgca ttttcatcac agaaaagagt 3900

 tgcatttgta ttaacaagaa atttgtatac ccacgcttca gctactatct 3950

 aatcatcacc cgaagattta agatacacca aatttcagtt tgtttgtaac 4000

 attgttcatc tttagtgcac tttgttttat ataataaagt atgcctgtta 4050

 tattaaataa taagaatatg gcaattagcg atatagcata cccaaacaaa 4100

 gatgttctcg atacagtctg gcaaagacta tcccaaggtt attttaatga 4150

 attcagacat tttttcctgt ggatatttct ccatcctaaa aaaagtggca 4200

 accaaggaaa atatttagat gcaacttact agagtgatga tgtgaaagaa 4250

 atggtgattc tggtatcatg gtgtttattt tctttcttat aactgcagag 4300

 aaaatatcct gactaaaaaa atttcatttt tttggattcc tttcttttac 4350

 aaattgtgct gaggcaacta tggcatagaa ataaacattt gacattaaaa 4400

 taagtaaaaa aaaaaaaaaa aaaaa 4425

<210> 600
<211> 521
<212> PRT
<213> Homo sapien

<400> 600
 Met Ser Glu Pro Lys Ala Ile Asp Pro Lys Leu Ser Thr Thr Asp
   1               5                  10                  15

 Arg Val Val Lys Ala Val Pro Phe Pro Pro Ser His Arg Leu Thr
                  20                  25                  30

 Ala Lys Glu Val Phe Asp Asn Asp Gly Lys Pro Arg Val Asp Ile
                  35                  40                  45

 Leu Lys Ala His Leu Met Lys Glu Gly Arg Leu Glu Glu Ser Val
                  50                  55                  60

 Ala Leu Arg Ile Ile Thr Glu Gly Ala Ser Ile Leu Arg Gln Glu
                  65                  70                  75

 Lys Asn Leu Leu Asp Ile Asp Ala Pro Val Thr Val Cys Gly Asp
                  80                  85                  90

 Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu Val Gly
                  95                 100                 105

 Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr Val
                 110                 115                 120

 Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Ala
                 125                 130                 135

 Leu Lys Ile Leu Tyr Pro Lys Thr Leu Phe Leu Leu Arg Gly Asn
                 140                 145                 150

 His Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu
                 155                 160                 165

 Cys Lys Ile Lys Tyr Ser Glu Arg Val Tyr Asp Ala Cys Met Asp
                 170                 175                 180

 Ala Phe Asp Cys Leu Pro Leu Ala Ala Leu Met Asn Gln Gln Phe
                 185                 190                 195

 Leu Cys Val His Gly Gly Leu Ser Pro Glu Ile Asn Thr Leu Asp
                 200                 205                 210

 Asp Ile Arg Lys Leu Asp Arg Phe Lys Glu Pro Pro Ala Tyr Gly
                 215                 220                 225

 Pro Met Cys Asp Ile Leu Trp Ser Asp Pro Leu Glu Asp Phe Gly
                 230                 235                 240

 Asn Glu Lys Thr Gln Glu His Phe Thr His Asn Thr Val Arg Gly
                 245                 250                 255

 Cys Ser Tyr Phe Tyr Ser Tyr Pro Ala Val Cys Glu Phe Leu Gln
                 260                 265                 270

 His Asn Asn Leu Leu Ser Ile Leu Arg Ala His Glu Ala Gln Asp
                 275                 280                 285

 Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln Thr Thr Gly Phe Pro
                 290                 295                 300

 Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr Leu Asp Val Tyr
                 305                 310                 315

 Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn Val Met Asn
                 320                 325                 330

 Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu Pro Asn
                 335                 340                 345

 Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu Lys
                 350                 355                 360

 Val Thr Glu Met Leu Val Asn Val Leu Asn Ile Cys Ser Asp Asp
                 365                 370                 375

 Glu Leu Gly Ser Glu Glu Asp Gly Phe Asp Gly Ala Thr Ala Ala
                 380                 385                 390

 Ala Arg Lys Glu Val Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys
                 395                 400                 405

 Met Ala Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val
                 410                 415                 420

 Leu Thr Leu Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly
                 425                 430                 435

 Val Leu Ser Gly Gly Lys Gln Thr Leu Gln Ser Ala Thr Val Glu
                 440                 445                 450

 Ala Ile Glu Ala Asp Glu Ala Ile Lys Gly Phe Ser Pro Gln His
                 455                 460                 465

 Lys Ile Thr Ser Phe Glu Glu Ala Lys Gly Leu Asp Arg Ile Asn
                 470                 475                 480

 Glu Arg Met Pro Pro Arg Arg Asp Ala Met Pro Ser Asp Ala Asn
                 485                 490                 495

 Leu Asn Ser Ile Asn Lys Ala Leu Thr Ser Glu Thr Asn Gly Thr
                 500                 505                 510

 Asp Ser Asn Gly Ser Asn Ser Ser Asn Ile Gln
                 515                 520

<210> 601
<211> 6245
<212> DNA
<213> Homo sapien

<400> 601
 gagaagaagt ggcaggtgat gctgaagcgg gggagaagcg gcagagccgg 50

 ccacacagtg caggggatgg agacaggtgc tgggctggtc ctcctgcagc 100

 atcctcagtt gttggagggc agtcatcctc aggccgtacc cagccagaga 150

 agaaaaagaa cagtgtgaag ccacgtgtga tagccgtcca acatcggctc 200

 ttccctccaa ttacattgta gttgattgtg tctcaaacca tgaattatgt 250

 gggacagctg gctgggcagg tgattgtcac tgtgaaggaa ctctacaagg 300

 gcattaacca ggccaccctc tctgggtgca ttgatgtcat cgtggtacag 350

 cagcaggatg gcagctatca gtgttcacct tttcacgttc ggtttggaaa 400

 gctgggagtc ctgagatcca aagagaaagt gattgatata gaaatcaacg 450

 gcagtgcagt ggatcttcac atgaagttgg gtgataacgg agaagctttc 500

 tttgttgagg agactgaaga agaatatgaa aagcttcctg cttaccttgc 550

 cacctcacca attcctactg aagatcagtt ctttaaagat attgacaccc 600

 ctttggtgaa atcgggtgga gatgaaacac catctcagag ttcagacatc 650

 tcacacgtct tggaaacaga gacaattttt actccaagtt ctgtgaaaaa 700

 gaaaaaacga aggagaaaga aatacaaaca ggacagtaag aaggaagagc 750

 aggccgcatc tgctgctgca gaagacacat gtgatgtagg cgtgagctcc 800

 gatgatgaca agggggccca ggcagcacga ggatcttcaa atgcttcctt 850

 gaaagaagaa gaatgtaaag agcctttgct cttccattct ggggatcatt 900

 accccttatc tgatggagat tggtcccctt tagagaccac ctatccccag 950

 acagcgtgtc ctaagagtga ttcagagctg gaggtgaaac ctgcggagag 1000

 cctgctcaga tcagagtctc acatggagtg gacgtggggc ggattcccag 1050

 agtccaccaa ggtcagcaaa agagaacgat ctgaccatca tcctaggaca 1100

 gctacaatta caccatcaga aaatactcat tttcgggtaa ttcccagtga 1150

 ggacaacctc atcagtgaag ttgagaagga tgcttccatg gaagacactg 1200

 tctgtaccat agtgaagccc aaacccagag ccctgggtac acagatgagc 1250

 gacccaacat ctgtggcaga gcttctcgaa cctcctcttg agagtactca 1300

 gatttcatct atgttagatg ctgaccacct tcccaacgca gccttagcgg 1350

 aggcgccctc agaatccaaa ccggcagcta aagtagactc gccgtcaaag 1400

 aagaaaggtg ttcacaaaag aagccaacac cagggacctg atgatattta 1450

 ccttgatgac ttaaagggtc tagaacctga agttgcagct ctttatttcc 1500

 ctaaaagtga atcggagccc ggttccaggc agtggcccga gtctgacaca 1550

 ctctctggct cccagtcccc acagtccgtg ggaagcgcag ctgcagatag 1600

 cggcaccgag tgcctctcag attctgccat ggacttgcct gacgttaccc 1650

 tctccctttg cgggggcctc agtgaaaatg gagaaatttc aaaagaaaaa 1700

 ttcatggagc atatcattac ttatcacgaa tttgcagaaa accctggact 1750

 tatagacaat cctaaccttg taataaggat atataatcgt tactataact 1800

 gggctttggc agctcccatg atccttagct tgcaagtatt ccagaagagc 1850

 ttgcctaagg ccacagttga gtcctgggtg aaagacaaga tgccaaagaa 1900

 atctggtcgc tggtggtttt ggcgaaagag agaaagcatg accaaacagc 1950

 tgccagaatc caaggaggga aaatctgagg caccgccagc cagtgacctg 2000

 ccatccagct ccaaggagcc ggccggtgcc aggccggccg agaatgactc 2050

 ctcgagtgac gagggatcac aggagctcga agaatccatc acagtggacc 2100

 ccatccccac agagcccctg agccacggca gcacaacttc atataagaag 2150

 tctctccgcc tctcctcaga ccagatcgca aaactgaagc tccacgatgg 2200

 cccaaatgat gttgtgttta gtattacaac ccagtatcaa ggcacctgtc 2250

 gctgtgcagg gaccatttac ctgtggaact ggaatgacaa gatcatcatt 2300

 tctgatattg atgggacaat aaccaagtcg gatgctttgg gacagattct 2350

 cccacagctg ggcaaagact ggacccacca gggtatagca aagctctacc 2400

 attccatcaa tgagaatggc tacaagtttc tgtactgctc ggctcgtgcc 2450

 atcggcatgg ccgacatgac ccgtggctac ctgcactggg tcaatgacaa 2500

 gggcacaatc ttgccccggg gccccctgat gctgtccccc agcagcttgt 2550

 tctccgcctt ccacagagaa gtgatagaaa agaaaccaga gaagttcaaa 2600

 attgagtgtc taaatgatat caagaatctg tttgccccgt ctaagcagcc 2650

 cttctatgct gcctttggaa accgtccaaa tgatgtctat gcctacacac 2700

 aagttggagt tccagactgt agaatattca ccgtgaaccc caagggtgaa 2750

 ttaatacaag aaagaaccaa aggaaacaag tcatcgtatc acaggctgag 2800

 tgagctcgtg gagcatgtgt tcccccttct cagtaaggag cagaattccg 2850

 cttttccctg cccggagttc agctccttct gctactggcg agacccgatc 2900

 cctgaagtgg acctggatga cctgtcttga ggcggcacct cagtgggtgg 2950

 gcagggcttg gtccccctcc ccacagcaag ggaaggcagc tggctcttct 3000

 gctgacctca gataccagcc ttccccagcg gggacgggtg cttctggagc 3050

 tggtcccgcc atcctccttt gccttcccag gccagctgct caggctcggc 3100

 aggtctgcag ctcagctcct ggaaggagaa gggaggaact gggcctgggg 3150

 ctggaggcct gggatccctc ctttgtgggt cgcacacatg tttcctgctg 3200

 tgagctgggg cctccttcca ttgcatcatt ttaaaggaag aaaaaagcag 3250

 ctaaaaaaga gtggaccaaa acactgcaca cagtgaagtg ttccagtttc 3300

 cactgggcag ttgaggtggc ttctgtaacc agggctgtct tcagatgtca 3350

 gggtccctga actgctgcgg gcccagtcag tgatgctggc tgaagctgcc 3400

 tgtgcacgtt tcttctctgg tcgcctcatt tcctgctaca ctgaaggggt 3450

 cagctgctcc agtgggccaa gttgggcagg acccccgccc ctgcagggcc 3500

 catgcaccag agccactgag cccagtccca taaacctggc cctctttggg 3550

 gaaagatccc cacagagcat cctcctctca tctgtgacaa ctccacgagc 3600

 ccttaatttc ttagtcctca ccagaagaac aggtctcaca agtatatatt 3650

 tgatgtctgt aataaaagtg ggaaggtggg tcttaaaaca gaccaaaccc 3700

 cgccccgccc ccaacaactc tgcttttagg gaggcctccg aaatgcagat 3750

 aggcggttga gtggggtcct gggaagagcg ctgaatccct ctgcttgctg 3800

 cctggtgtgg gcctttggaa agcatcttgc cttgggacag gatttctaaa 3850

 attctgtgat tcagatttgt cagggaagca cagtgaagct tgcttaaagg 3900

 cactggccag cagtgtgtga ctttggcttt tgggatcaca ccctgtaatc 3950

 gggcccgtgg aagcagcgtc aaagaggggt cttggagctc ctatggagca 4000

 gactgccccc cgagcagtgt ccccagccta gccctgtgag accccatggg 4050

 gacacgggtg cctatgtatt ttcactaaaa tatacatggt agctccattt 4100

 actgatgcgg ttgtaatgag ctcacatcgt gtctgaagag atggcaccag 4150

 ggaaaggtgt gccataagct gctccagagc ttttggtatg ctgagtgttg 4200

 acagagctgc actcttaaca tcaagagaac tgtcaggagc ccagaaccaa 4250

 ccccaggtct tggtctccat tggcgagaac acaggacgtg gtggttcctg 4300

 agcagagagg gatctgcaga tacaggcttg gcgctcgggg tggtctcgtg 4350

 gccaactctt catgcccctg ccgttgtagt ggaacctcta catgttttag 4400

 tttgcttcac ctaaaataat gctgatctag agatagagaa ataggggtgg 4450

 ttatttttcc agattggaga gttgaaagtc cctgactgat ttcagccatt 4500

 ttcctagtgc ttgtcggatg cagagacaat gttgaaatcc cctaaacaca 4550

 gttctcagtg gcaaaaccta ggaaggctca tgttcccaga gaagggacca 4600

 catgagcctt ctcccatgca aagcttcccc cagcttaaat agttgataag 4650

 gactaattgt ttaatgagtt tatttatcta cagtaggtta gggatcctgg 4700

 gttctgttta tatgaagttc ttcccagttt gtgaattcta gtacagcagc 4750

 catgcagcca ccttatttca tagatgccat ctgtgtgtcc tcttgactac 4800

 cttctattta gaggaagaat gagagctttg tgtgtttaac tgagcttata 4850

 gtaggacttc tttgcatatg tatggtactg aaaaatctta atatacatct 4900

 ttaatccttt ttaggttgtc ctttaaagag tttttgacta gtttcttttt 4950

 cttgacagct cttctctttg gacacatggg ccttcttaga gggttcagtc 5000

 taggacccgg ctctcctggc cctgtgttga gggtagctgg tccctctgtc 5050

 cctgtgtctg ctagcactag actttgttgc tgcagattga tccagtgggt 5100

 acataggcta attaatgtga gtctttttcc ttgtttaaag gagtccctct 5150

 tgctgaaagt agatgattac tattgctgta gtgttaggaa agtattaagt 5200

 ttgtgctgaa aatccattgc catttggtac aaatgacatt tgttctttct 5250

 gtgaaagaga tgccctcgag tgtgtttgta cacaaaccct taggatggtg 5300

 agttgaagca tcaccctcgc gctatcttca gtgacgggtg acggctcagg 5350

 gagatggcag gcagattggg ctctaagtca ttattctctc agttactcca 5400

 ttggtgaaat ggccctttcc ctctttgcag ttcagtctaa gtctcgtatt 5450

 tgctttgctg tctgtgtgct gaagctcgtc ccgtgtgagt tgctgtctgc 5500

 cccttgtcag gctgtgaggt gctcgtgtag acctggagca tgcaggctgc 5550

 ctccgttttt gggtactgtg ttgtgttttg ctctgtctaa aaacatctgc 5600

 atagttttca actggaaaaa gaaaaaactt aaaaatggga tgtcctaaaa 5650

 tgaaagctgc tcaaagtcac agaacaaccg agggacaaag gagattggat 5700

 gactgggaag cgctggcccg gaacagcccc tgcaactgtg gggcctgcac 5750

 acagcccttc cacagttggc actgcaggtg caggccaacc ctttaaagaa 5800

 taaacaagga agtcagctct ttcacttttt acaagttggc aaaaacagac 5850

 ttccggggaa tttcgatgtt ttcccgtgtt gtagagcttc cagggtttaa 5900

 taaaactggt taaaaattga gtctttccct gaagtaagtg ctctttccag 5950

 atgaaaacta ctcttttggt tttgtttgaa agtaagaaag ggaggggaaa 6000

 ctttgctctt ttaataatta tgttcagcct atgatgaagt atttgattat 6050

 tagacagcaa tgtcactaat aagttttaag ttgtccaaag ttaattgtaa 6100

 acatcatcag tacagtactc ttagttacag taaagcaatt gttgcaagat 6150

 gaatggctaa tattttggtg cagtgtttga tgttcaaaac aaaatgttac 6200

 aacaataaac gaacataaca taaactgaaa aaaaaaaaaa aaaaa 6245

<210> 602
<211> 896
<212> PRT
<213> Homo sapien

<400> 602
 Met Asn Tyr Val Gly Gln Leu Ala Gly Gln Val Ile Val Thr Val
   1               5                  10                  15

 Lys Glu Leu Tyr Lys Gly Ile Asn Gln Ala Thr Leu Ser Gly Cys
                  20                  25                  30

 Ile Asp Val Ile Val Val Gln Gln Gln Asp Gly Ser Tyr Gln Cys
                  35                  40                  45

 Ser Pro Phe His Val Arg Phe Gly Lys Leu Gly Val Leu Arg Ser
                  50                  55                  60

 Lys Glu Lys Val Ile Asp Ile Glu Ile Asn Gly Ser Ala Val Asp
                  65                  70                  75

 Leu His Met Lys Leu Gly Asp Asn Gly Glu Ala Phe Phe Val Glu
                  80                  85                  90

 Glu Thr Glu Glu Glu Tyr Glu Lys Leu Pro Ala Tyr Leu Ala Thr
                  95                 100                 105

 Ser Pro Ile Pro Thr Glu Asp Gln Phe Phe Lys Asp Ile Asp Thr
                 110                 115                 120

 Pro Leu Val Lys Ser Gly Gly Asp Glu Thr Pro Ser Gln Ser Ser
                 125                 130                 135

 Asp Ile Ser His Val Leu Glu Thr Glu Thr Ile Phe Thr Pro Ser
                 140                 145                 150

 Ser Val Lys Lys Lys Lys Arg Arg Arg Lys Lys Tyr Lys Gln Asp
                 155                 160                 165

 Ser Lys Lys Glu Glu Gln Ala Ala Ser Ala Ala Ala Glu Asp Thr
                 170                 175                 180

 Cys Asp Val Gly Val Ser Ser Asp Asp Asp Lys Gly Ala Gln Ala
                 185                 190                 195

 Ala Arg Gly Ser Ser Asn Ala Ser Leu Lys Glu Glu Glu Cys Lys
                 200                 205                 210

 Glu Pro Leu Leu Phe His Ser Gly Asp His Tyr Pro Leu Ser Asp
                 215                 220                 225

 Gly Asp Trp Ser Pro Leu Glu Thr Thr Tyr Pro Gln Thr Ala Cys
                 230                 235                 240

 Pro Lys Ser Asp Ser Glu Leu Glu Val Lys Pro Ala Glu Ser Leu
                 245                 250                 255

 Leu Arg Ser Glu Ser His Met Glu Trp Thr Trp Gly Gly Phe Pro
                 260                 265                 270

 Glu Ser Thr Lys Val Ser Lys Arg Glu Arg Ser Asp His His Pro
                 275                 280                 285

 Arg Thr Ala Thr Ile Thr Pro Ser Glu Asn Thr His Phe Arg Val
                 290                 295                 300

 Ile Pro Ser Glu Asp Asn Leu Ile Ser Glu Val Glu Lys Asp Ala
                 305                 310                 315

 Ser Met Glu Asp Thr Val Cys Thr Ile Val Lys Pro Lys Pro Arg
                 320                 325                 330

 Ala Leu Gly Thr Gln Met Ser Asp Pro Thr Ser Val Ala Glu Leu
                 335                 340                 345

 Leu Glu Pro Pro Leu Glu Ser Thr Gln Ile Ser Ser Met Leu Asp
                 350                 355                 360

 Ala Asp His Leu Pro Asn Ala Ala Leu Ala Glu Ala Pro Ser Glu
                 365                 370                 375

 Ser Lys Pro Ala Ala Lys Val Asp Ser Pro Ser Lys Lys Lys Gly
                 380                 385                 390

 Val His Lys Arg Ser Gln His Gln Gly Pro Asp Asp Ile Tyr Leu
                 395                 400                 405

 Asp Asp Leu Lys Gly Leu Glu Pro Glu Val Ala Ala Leu Tyr Phe
                 410                 415                 420

 Pro Lys Ser Glu Ser Glu Pro Gly Ser Arg Gln Trp Pro Glu Ser
                 425                 430                 435

 Asp Thr Leu Ser Gly Ser Gln Ser Pro Gln Ser Val Gly Ser Ala
                 440                 445                 450

 Ala Ala Asp Ser Gly Thr Glu Cys Leu Ser Asp Ser Ala Met Asp
                 455                 460                 465

 Leu Pro Asp Val Thr Leu Ser Leu Cys Gly Gly Leu Ser Glu Asn
                 470                 475                 480

 Gly Glu Ile Ser Lys Glu Lys Phe Met Glu His Ile Ile Thr Tyr
                 485                 490                 495

 His Glu Phe Ala Glu Asn Pro Gly Leu Ile Asp Asn Pro Asn Leu
                 500                 505                 510

 Val Ile Arg Ile Tyr Asn Arg Tyr Tyr Asn Trp Ala Leu Ala Ala
                 515                 520                 525

 Pro Met Ile Leu Ser Leu Gln Val Phe Gln Lys Ser Leu Pro Lys
                 530                 535                 540

 Ala Thr Val Glu Ser Trp Val Lys Asp Lys Met Pro Lys Lys Ser
                 545                 550                 555

 Gly Arg Trp Trp Phe Trp Arg Lys Arg Glu Ser Met Thr Lys Gln
                 560                 565                 570

 Leu Pro Glu Ser Lys Glu Gly Lys Ser Glu Ala Pro Pro Ala Ser
                 575                 580                 585

 Asp Leu Pro Ser Ser Ser Lys Glu Pro Ala Gly Ala Arg Pro Ala
                 590                 595                 600

 Glu Asn Asp Ser Ser Ser Asp Glu Gly Ser Gln Glu Leu Glu Glu
                 605                 610                 615

 Ser Ile Thr Val Asp Pro Ile Pro Thr Glu Pro Leu Ser His Gly
                 620                 625                 630

 Ser Thr Thr Ser Tyr Lys Lys Ser Leu Arg Leu Ser Ser Asp Gln
                 635                 640                 645

 Ile Ala Lys Leu Lys Leu His Asp Gly Pro Asn Asp Val Val Phe
                 650                 655                 660

 Ser Ile Thr Thr Gln Tyr Gln Gly Thr Cys Arg Cys Ala Gly Thr
                 665                 670                 675

 Ile Tyr Leu Trp Asn Trp Asn Asp Lys Ile Ile Ile Ser Asp Ile
                 680                 685                 690

 Asp Gly Thr Ile Thr Lys Ser Asp Ala Leu Gly Gln Ile Leu Pro
                 695                 700                 705

 Gln Leu Gly Lys Asp Trp Thr His Gln Gly Ile Ala Lys Leu Tyr
                 710                 715                 720

 His Ser Ile Asn Glu Asn Gly Tyr Lys Phe Leu Tyr Cys Ser Ala
                 725                 730                 735

 Arg Ala Ile Gly Met Ala Asp Met Thr Arg Gly Tyr Leu His Trp
                 740                 745                 750

 Val Asn Asp Lys Gly Thr Ile Leu Pro Arg Gly Pro Leu Met Leu
                 755                 760                 765

 Ser Pro Ser Ser Leu Phe Ser Ala Phe His Arg Glu Val Ile Glu
                 770                 775                 780

 Lys Lys Pro Glu Lys Phe Lys Ile Glu Cys Leu Asn Asp Ile Lys
                 785                 790                 795

 Asn Leu Phe Ala Pro Ser Lys Gln Pro Phe Tyr Ala Ala Phe Gly
                 800                 805                 810

 Asn Arg Pro Asn Asp Val Tyr Ala Tyr Thr Gln Val Gly Val Pro
                 815                 820                 825

 Asp Cys Arg Ile Phe Thr Val Asn Pro Lys Gly Glu Leu Ile Gln
                 830                 835                 840

 Glu Arg Thr Lys Gly Asn Lys Ser Ser Tyr His Arg Leu Ser Glu
                 845                 850                 855

 Leu Val Glu His Val Phe Pro Leu Leu Ser Lys Glu Gln Asn Ser
                 860                 865                 870

 Ala Phe Pro Cys Pro Glu Phe Ser Ser Phe Cys Tyr Trp Arg Asp
                 875                 880                 885

 Pro Ile Pro Glu Val Asp Leu Asp Asp Leu Ser
                 890                 895

<210> 603
<211> 4322
<212> DNA
<213> Homo sapien

<400> 603
 gggaccgacg acacgccccc ctctcctcct ttgttccggg ggtcggcggc 50

 cgctctcctg ccagagctcg ggatctcggc cccgggaggc gggcgctcgg 100

 gcgcagccgc gaagatgccg ttggaactga cgcagagccg agtgcagaag 150

 atctgggtgc ccgtggacca caggccctcg ttgcccagat cctgtgggcc 200

 aaagctgacc aactccccca ccgtcatcgt catggtgggc ctccccgccc 250

 ggggcaagac ctacatctcc aagaagctga ctcgctacct caactggatt 300

 ggcgtcccca caaaagtgtt caacgtcggg gagtatcgcc gggaggctgt 350

 gaagcagtac agctcctaca acttcttccg ccccgacaat gaggaagcca 400

 tgaaagtccg gaagcaatgt gccttagctg ccttgagaga tgtcaaaagc 450

 tacctggcga aagaaggggg acaaattgcg gttttcgatg ccaccaatac 500

 tactagagag aggagacaca tgatccttca ttttgccaaa gaaaatgact 550

 ttaaagcgtt tttcatcgag tcggtgtgcg acgaccctac agttgtggcc 600

 tccaatatca tggaagttaa aatctccagc ccggattaca aagactgcaa 650

 ctcggcagaa gccatggacg acttcatgaa gaggatcagt tgctatgaag 700

 ccagctacca gcccctcgac cccgacaaat gcgacaggga cttgtcgctg 750

 atcaaggtga ttgacgtggg ccggaggttc ctggtgaacc gggtgcagga 800

 ccacatccag agccgcatcg tgtactacct gatgaacatc cacgtgcagc 850

 cgcgtaccat ctacctgtgc cggcacggcg agaacgagca caacctccag 900

 ggccgcatcg ggggcgactc aggcctgtcc agccggggca agaagtttgc 950

 cagtgctctg agcaagttcg tggaggagca gaacctgaag gacctgcgcg 1000

 tgtggaccag ccagctgaag agcaccatcc agacggccga ggcgctgcgg 1050

 ctgccctacg agcagtggaa ggcgctcaat gagatcgacg cgggcgtctg 1100

 tgaggagctg acctacgagg agatcaggga cacctaccct gaggagtatg 1150

 cgctgcggga gcaggacaag tactattacc gctaccccac cggggagtcc 1200

 taccaggacc tggtccagcg cttggagcca gtgatcatgg agctggagcg 1250

 gcaggagaat gtgctggtca tctgccacca ggccgtcctg cgctgcctgc 1300

 ttgcctactt cctggataag agtgcagagg agatgcccta cctgaaatgc 1350

 cctcttcaca ccgtcctgaa actgacgcct gtcgcttatg gctgccgtgt 1400

 ggaatccatc tacctgaacg tggagtccgt ctgcacacac cgggagaggt 1450

 cagaggatgc aaagaaggga cctaacccgc tcatgagacg caatagtgtc 1500

 accccgctag ccagccccga acccaccaaa aagcctcgca tcaacagctt 1550

 tgaggagcat gtggcctcca cctcggccgc cctgcccagc tgcctgcccc 1600

 cggaggtgcc cacgcagctg cctggacaaa acatgaaagg ctcccggagc 1650

 agcgctgact cctccaggaa acactgaggc agacgtgtcg gttccattcc 1700

 atttccattt ctgcagctta gcttgtgtcc tgccctccgc ccgaggcaaa 1750

 acgtatcctg aggacttctt ccggagaggg tggggtggag cagcggggga 1800

 gccttggccg aagagaacca tgcttggcac cgtctgtgtc ccctcggccg 1850

 ctggacacca gaaagccacg tgggtccctg gcgcctgcct ttagcctggg 1900

 ggcccccacc tccactctct gggttcctag gaatgtccag cctcggagac 1950

 cttcacaaag ccttgggagg gtgatgagtg ctggtcctga caagaggccg 2000

 ctggggacac tgtccgtttt gtttcgtttc tgtgatctcc cggcacgttt 2050

 ggagctggga agaccacact ggtggcagaa tcctaaaatt aaaggaggca 2100

 gcctcctagt tgctgaaagt taaggaatgt gtaaaacctc cacgtgactg 2150

 tttggtgcat cttgacctgg gaagacgcct catgggaacg aacttggaca 2200

 ggtgttgggt tgacccctct tctgcaggaa gtccctgagc tgagacgcaa 2250

 agttggctgg gtggtggtcg gcaccctggc tcctgcaggt ccacacacct 2300

 tccaggcctg tggcctgcct ccaaagatgt gcaagggcag gctggctgca 2350

 cggggagagg gaagtatttt gccgaaatat gagaactggg gcctcctgct 2400

 cccagggagc tccagggccc ctctctcctc ccacctggac ttggggggaa 2450

 ctgagaaaca ctttcctgga gctgctggct tttgcacttt tttgatggca 2500

 gaagtgtgac ctgagagtcc caccttctct tcaggaacgt agatgtcggg 2550

 gtgtcttgcc ctggggggct tggaacctct gaaggtgggg agcggaacac 2600

 ctggcatcct tccccagcac ttgcattacg gtccctgctc ttccaaggtg 2650

 gggacagtgg cccaagcaag gcctcacacg cagccacttc ttcaagagct 2700

 gcctgcacac tgtcttggag catctgcctt gtgcctggca ctctgccggt 2750

 gccttgggaa ggtcggtaag agtggacttt gtcctgggct tcccttcatg 2800

 gcgtctagac acttttgtgg tgatggaaag catgggacct gtcgtctcag 2850

 cctgttggtt tctcctcatt gcctcaaacc ctggggtagg tggaacgggg 2900

 ggtctcgtgc ccagatgaaa ccatttggaa actcggcagc agagtttgtc 2950

 caaatgaccc ttttcaggat gtctcaaagc ttgtgccaaa ggtcactttt 3000

 ctttcctgcc ttctgctgtg agccctgaga tcctcctccc agctcaaggg 3050

 acaggtcctg ggtgagggtg ggagatttag acacctgaaa ctgggcgtgg 3100

 agagaagagc cgttgctgtt tgttttttgg gaagagcttt taaagaatgc 3150

 atattttttt acctggttgg aattgagtag gaactgaggc tgtgcttcag 3200

 gtatggtaca atcaagtggg ggattttcat gctgaaccca ttcaaagccc 3250

 tccccgtccc cgcatttcca ggccaccctt tggctggcgt ctgctggaga 3300

 ggatgtctct gtcgcattcc cgtgcagctc agctcgcgca ggttttctct 3350

 ctctccctgg atgttgagct ctcatcagaa tatgtgggtg gggggtggac 3400

 gtgcacgggt gcatgattgt gcttaacttg gttgtatttt tcgatttgac 3450

 atggaagcct gttgctttgc tctagagaat agtttctcgt gtccccttcg 3500

 cacgcctcat tctttgaacc tcatctctga tgtttgatac agatgggggc 3550

 ttgatagctg tggtcccctt tcccttctga ctacgtgaaa atcaatacct 3600

 aaatacagaa gccttggtct aaacaccgag acttttagtt tgcgaagggg 3650

 cttagatagg gagagaggta acatgaatct ggacagggga gggagatact 3700

 atagaaagga gaacactgca tactttgcaa agccagtgac ctccttttga 3750

 aggggacatt ggacgggggc cgggggcggg ggttcggttt gactaccgtc 3800

 atgaactttt ggcgtatact gattcctcca actctccacc ccacaaaata 3850

 acggggacca atatttttaa ctttgcctat ttgtttttgg gtgagtttcc 3900

 cccctccatt attctgtcct gagaccacgg gcaaagctct tccattttga 3950

 gagagaagaa aaactgtttg gaaccacacc aatgatattt ttctttgtaa 4000

 tacttgaaat ttattttttt attattttga tagcagatgt gctatttatt 4050

 tatttaatat atgtataagg agtcctaaac aatagaaagc tgtagaagct 4100

 gtagagatag gcttcagttg ttaattggtt tggagcctcc tatgtgtgac 4150

 ttatgactct ctgtgttctg tgtatttgtc tgaattaatg acctgggata 4200

 taaagctatg ctagctttca aacaggagat gccttcagaa agctttgtat 4250

 attttgcagt tgccagacca ataaaatacc tggttgaaat acatggacga 4300

 aaaaaaaaaa aaaaaaaaaa aa 4322

<210> 604
<211> 520
<212> PRT
<213> Homo sapien

<400> 604
 Met Pro Leu Glu Leu Thr Gln Ser Arg Val Gln Lys Ile Trp Val
   1               5                  10                  15

 Pro Val Asp His Arg Pro Ser Leu Pro Arg Ser Cys Gly Pro Lys
                  20                  25                  30

 Leu Thr Asn Ser Pro Thr Val Ile Val Met Val Gly Leu Pro Ala
                  35                  40                  45

 Arg Gly Lys Thr Tyr Ile Ser Lys Lys Leu Thr Arg Tyr Leu Asn
                  50                  55                  60

 Trp Ile Gly Val Pro Thr Lys Val Phe Asn Val Gly Glu Tyr Arg
                  65                  70                  75

 Arg Glu Ala Val Lys Gln Tyr Ser Ser Tyr Asn Phe Phe Arg Pro
                  80                  85                  90

 Asp Asn Glu Glu Ala Met Lys Val Arg Lys Gln Cys Ala Leu Ala
                  95                 100                 105

 Ala Leu Arg Asp Val Lys Ser Tyr Leu Ala Lys Glu Gly Gly Gln
                 110                 115                 120

 Ile Ala Val Phe Asp Ala Thr Asn Thr Thr Arg Glu Arg Arg His
                 125                 130                 135

 Met Ile Leu His Phe Ala Lys Glu Asn Asp Phe Lys Ala Phe Phe
                 140                 145                 150

 Ile Glu Ser Val Cys Asp Asp Pro Thr Val Val Ala Ser Asn Ile
                 155                 160                 165

 Met Glu Val Lys Ile Ser Ser Pro Asp Tyr Lys Asp Cys Asn Ser
                 170                 175                 180

 Ala Glu Ala Met Asp Asp Phe Met Lys Arg Ile Ser Cys Tyr Glu
                 185                 190                 195

 Ala Ser Tyr Gln Pro Leu Asp Pro Asp Lys Cys Asp Arg Asp Leu
                 200                 205                 210

 Ser Leu Ile Lys Val Ile Asp Val Gly Arg Arg Phe Leu Val Asn
                 215                 220                 225

 Arg Val Gln Asp His Ile Gln Ser Arg Ile Val Tyr Tyr Leu Met
                 230                 235                 240

 Asn Ile His Val Gln Pro Arg Thr Ile Tyr Leu Cys Arg His Gly
                 245                 250                 255

 Glu Asn Glu His Asn Leu Gln Gly Arg Ile Gly Gly Asp Ser Gly
                 260                 265                 270

 Leu Ser Ser Arg Gly Lys Lys Phe Ala Ser Ala Leu Ser Lys Phe
                 275                 280                 285

 Val Glu Glu Gln Asn Leu Lys Asp Leu Arg Val Trp Thr Ser Gln
                 290                 295                 300

 Leu Lys Ser Thr Ile Gln Thr Ala Glu Ala Leu Arg Leu Pro Tyr
                 305                 310                 315

 Glu Gln Trp Lys Ala Leu Asn Glu Ile Asp Ala Gly Val Cys Glu
                 320                 325                 330

 Glu Leu Thr Tyr Glu Glu Ile Arg Asp Thr Tyr Pro Glu Glu Tyr
                 335                 340                 345

 Ala Leu Arg Glu Gln Asp Lys Tyr Tyr Tyr Arg Tyr Pro Thr Gly
                 350                 355                 360

 Glu Ser Tyr Gln Asp Leu Val Gln Arg Leu Glu Pro Val Ile Met
                 365                 370                 375

 Glu Leu Glu Arg Gln Glu Asn Val Leu Val Ile Cys His Gln Ala
                 380                 385                 390

 Val Leu Arg Cys Leu Leu Ala Tyr Phe Leu Asp Lys Ser Ala Glu
                 395                 400                 405

 Glu Met Pro Tyr Leu Lys Cys Pro Leu His Thr Val Leu Lys Leu
                 410                 415                 420

 Thr Pro Val Ala Tyr Gly Cys Arg Val Glu Ser Ile Tyr Leu Asn
                 425                 430                 435

 Val Glu Ser Val Cys Thr His Arg Glu Arg Ser Glu Asp Ala Lys
                 440                 445                 450

 Lys Gly Pro Asn Pro Leu Met Arg Arg Asn Ser Val Thr Pro Leu
                 455                 460                 465

 Ala Ser Pro Glu Pro Thr Lys Lys Pro Arg Ile Asn Ser Phe Glu
                 470                 475                 480

 Glu His Val Ala Ser Thr Ser Ala Ala Leu Pro Ser Cys Leu Pro
                 485                 490                 495

 Pro Glu Val Pro Thr Gln Leu Pro Gly Gln Asn Met Lys Gly Ser
                 500                 505                 510

 Arg Ser Ser Ala Asp Ser Ser Arg Lys His
                 515                 520

<210> 605
<211> 2446
<212> DNA
<213> Homo sapien

<400> 605
 gcgccgcggc gcggagtccc ggctgcggga tagaccgagg gccatggccg 50

 cctctcccgg acccgccggc gttggcggcg ccggagcagt ctacggctcc 100

 ggctcttcgg gcttcgccct cgactcggga ctggagatca aaactcgctc 150

 ggtggagcag acgctactcc cgctggtttc tcagatcacc acgcttatta 200

 atcataaaga taataccaaa aagtctgata aaactctgca agcaattcag 250

 cgtgtaggac aagctgtcaa cttggcagtt ggaagatttg ttaaagtagg 300

 agaagctata gccaatgaaa actgggattt gaaagaagaa ataaatattg 350

 cttgtattga agctaaacaa gcaggagaaa caattgcagc acttacagac 400

 ataaccaact tgaaccatct ggaatctgat gggcagatca caatttttac 450

 agacaaaaca ggagtgataa aggctgcaag attacttctt tcttcagtga 500

 caaaagtgtt gttgctggca gaccgagtag tcattaaaca gataataaca 550

 tcaagaaata aggttctcgc aactatggaa agactagaga aagtgaatag 600

 ctttcaagag tttgtccaaa tattcagtca atttggaaat gaaatggtgg 650

 agtttgcaca tctgagtgga gatagacaaa atgatttgaa agatgaaaag 700

 aaaaaggcaa aaatggcagc agctagggca gttcttgaaa agtgtacaat 750

 gatgcttctc acagcttcaa agacatgtct gaggcatcct aactgcgaat 800

 cagcccataa aaacaaagaa ggagtatttg accgtatgaa agtggcattg 850

 gataaggtca ttgaaattgt gactgactgt aaaccgaatg gagagactga 900

 catttcatct atcagtattt ttactggaat taaggaattc aagatgaata 950

 ttgaagctct tcgggagaat ctttattttc agtccaaaga gaacctttct 1000

 gtgacattgg aagtcatctt ggagcgtatg gaggacttta ctgattctgc 1050

 ctacaccagc catgagcaca gagaacgcat cttggaactg tcaactcagg 1100

 cgagaatgga actgcagcag ttaatttctg tgtggattca agctcaaagc 1150

 aagaaaacaa aaagcatcgc tgaagaactg gaactcagta ttttgaaaat 1200

 cagtcacagt cttaatgaac ttaagaaaga acttcatagt acagcgacac 1250

 agctggcagc agatctatta aaataccatg ctgatcatgt ggttctaaaa 1300

 gcattaaaac ttactggagt agaaggaaat ttagaagctt tggctgaata 1350

 tgcctgtaaa ctctctgaac agaaagagca gcttgttgag acctgtcgat 1400

 tgttacgaca catatctggg acagaacctc tggaaataac ctgtatacat 1450

 gcagaggaga catttcaggt gactggccaa cagataattt ctgctgctga 1500

 aacattgaca ttgcatccat ctagtaaaat tgctaaagaa aacctagatg 1550

 tattttgtga agcttgggaa tcccaaatta gtgacatgtc aacactgctg 1600

 agagaaatca atgacgtgtt tgaaggaaga cgaggagaga agtatggcta 1650

 cctttcactt ccaaagccaa tgaagaataa tgcaaacctg aaatcattaa 1700

 agccagacaa gcctgactct gaggagcaag ccaagatagc aaagcttgga 1750

 cttaagctgg gtttgctcac ctctgacgct gactgcgaaa ttgagaagtg 1800

 ggaagatcag gagaatgaga ttgttcaata tggacggaac atgtccagta 1850

 tggcctattc tctgtattta tttactagag gagaggggcc actgaaaact 1900

 tcccaggatt taattcatca actagaggtt tttgctgcag agggtttaaa 1950

 gcttacttcc agtgttcaag ctttttcaaa acagctgaaa gacgatgaca 2000

 agcttatgct tctcctggaa ataaacaagc taattcctct atgccaccag 2050

 ctccagacag taactaagac ttctttgcag aataaagtat ttctaaaggt 2100

 tgacaagtgt attacgaaga caagatccat gatggctctc ttagtccaac 2150

 ttctttcact ttgttataaa ctgctgaaga agcttcagat ggaaaataac 2200

 ggatgggtct cagttacaaa taaggacact atggatagta aaacttgaga 2250

 agcttttggg gtcagatctc tggaacatca tgtgatgaag ctgacatttt 2300

 taaaaatcaa atgatccttt atcttttcag aaattcatca attttataaa 2350

 gaaaacaata ttgaaatttt gctctatttt ctgatcatga aactgattgt 2400

 aaagcttttt gacaactaat aaatgtcttg gtaattgcta gattct 2446

<210> 606
<211> 734
<212> PRT
<213> Homo sapien

<400> 606
 Met Ala Ala Ser Pro Gly Pro Ala Gly Val Gly Gly Ala Gly Ala
   1               5                  10                  15

 Val Tyr Gly Ser Gly Ser Ser Gly Phe Ala Leu Asp Ser Gly Leu
                  20                  25                  30

 Glu Ile Lys Thr Arg Ser Val Glu Gln Thr Leu Leu Pro Leu Val
                  35                  40                  45

 Ser Gln Ile Thr Thr Leu Ile Asn His Lys Asp Asn Thr Lys Lys
                  50                  55                  60

 Ser Asp Lys Thr Leu Gln Ala Ile Gln Arg Val Gly Gln Ala Val
                  65                  70                  75

 Asn Leu Ala Val Gly Arg Phe Val Lys Val Gly Glu Ala Ile Ala
                  80                  85                  90

 Asn Glu Asn Trp Asp Leu Lys Glu Glu Ile Asn Ile Ala Cys Ile
                  95                 100                 105

 Glu Ala Lys Gln Ala Gly Glu Thr Ile Ala Ala Leu Thr Asp Ile
                 110                 115                 120

 Thr Asn Leu Asn His Leu Glu Ser Asp Gly Gln Ile Thr Ile Phe
                 125                 130                 135

 Thr Asp Lys Thr Gly Val Ile Lys Ala Ala Arg Leu Leu Leu Ser
                 140                 145                 150

 Ser Val Thr Lys Val Leu Leu Leu Ala Asp Arg Val Val Ile Lys
                 155                 160                 165

 Gln Ile Ile Thr Ser Arg Asn Lys Val Leu Ala Thr Met Glu Arg
                 170                 175                 180

 Leu Glu Lys Val Asn Ser Phe Gln Glu Phe Val Gln Ile Phe Ser
                 185                 190                 195

 Gln Phe Gly Asn Glu Met Val Glu Phe Ala His Leu Ser Gly Asp
                 200                 205                 210

 Arg Gln Asn Asp Leu Lys Asp Glu Lys Lys Lys Ala Lys Met Ala
                 215                 220                 225

 Ala Ala Arg Ala Val Leu Glu Lys Cys Thr Met Met Leu Leu Thr
                 230                 235                 240

 Ala Ser Lys Thr Cys Leu Arg His Pro Asn Cys Glu Ser Ala His
                 245                 250                 255

 Lys Asn Lys Glu Gly Val Phe Asp Arg Met Lys Val Ala Leu Asp
                 260                 265                 270

 Lys Val Ile Glu Ile Val Thr Asp Cys Lys Pro Asn Gly Glu Thr
                 275                 280                 285

 Asp Ile Ser Ser Ile Ser Ile Phe Thr Gly Ile Lys Glu Phe Lys
                 290                 295                 300

 Met Asn Ile Glu Ala Leu Arg Glu Asn Leu Tyr Phe Gln Ser Lys
                 305                 310                 315

 Glu Asn Leu Ser Val Thr Leu Glu Val Ile Leu Glu Arg Met Glu
                 320                 325                 330

 Asp Phe Thr Asp Ser Ala Tyr Thr Ser His Glu His Arg Glu Arg
                 335                 340                 345

 Ile Leu Glu Leu Ser Thr Gln Ala Arg Met Glu Leu Gln Gln Leu
                 350                 355                 360

 Ile Ser Val Trp Ile Gln Ala Gln Ser Lys Lys Thr Lys Ser Ile
                 365                 370                 375

 Ala Glu Glu Leu Glu Leu Ser Ile Leu Lys Ile Ser His Ser Leu
                 380                 385                 390

 Asn Glu Leu Lys Lys Glu Leu His Ser Thr Ala Thr Gln Leu Ala
                 395                 400                 405

 Ala Asp Leu Leu Lys Tyr His Ala Asp His Val Val Leu Lys Ala
                 410                 415                 420

 Leu Lys Leu Thr Gly Val Glu Gly Asn Leu Glu Ala Leu Ala Glu
                 425                 430                 435

 Tyr Ala Cys Lys Leu Ser Glu Gln Lys Glu Gln Leu Val Glu Thr
                 440                 445                 450

 Cys Arg Leu Leu Arg His Ile Ser Gly Thr Glu Pro Leu Glu Ile
                 455                 460                 465

 Thr Cys Ile His Ala Glu Glu Thr Phe Gln Val Thr Gly Gln Gln
                 470                 475                 480

 Ile Ile Ser Ala Ala Glu Thr Leu Thr Leu His Pro Ser Ser Lys
                 485                 490                 495

 Ile Ala Lys Glu Asn Leu Asp Val Phe Cys Glu Ala Trp Glu Ser
                 500                 505                 510

 Gln Ile Ser Asp Met Ser Thr Leu Leu Arg Glu Ile Asn Asp Val
                 515                 520                 525

 Phe Glu Gly Arg Arg Gly Glu Lys Tyr Gly Tyr Leu Ser Leu Pro
                 530                 535                 540

 Lys Pro Met Lys Asn Asn Ala Asn Leu Lys Ser Leu Lys Pro Asp
                 545                 550                 555

 Lys Pro Asp Ser Glu Glu Gln Ala Lys Ile Ala Lys Leu Gly Leu
                 560                 565                 570

 Lys Leu Gly Leu Leu Thr Ser Asp Ala Asp Cys Glu Ile Glu Lys
                 575                 580                 585

 Trp Glu Asp Gln Glu Asn Glu Ile Val Gln Tyr Gly Arg Asn Met
                 590                 595                 600

 Ser Ser Met Ala Tyr Ser Leu Tyr Leu Phe Thr Arg Gly Glu Gly
                 605                 610                 615

 Pro Leu Lys Thr Ser Gln Asp Leu Ile His Gln Leu Glu Val Phe
                 620                 625                 630

 Ala Ala Glu Gly Leu Lys Leu Thr Ser Ser Val Gln Ala Phe Ser
                 635                 640                 645

 Lys Gln Leu Lys Asp Asp Asp Lys Leu Met Leu Leu Leu Glu Ile
                 650                 655                 660

 Asn Lys Leu Ile Pro Leu Cys His Gln Leu Gln Thr Val Thr Lys
                 665                 670                 675

 Thr Ser Leu Gln Asn Lys Val Phe Leu Lys Val Asp Lys Cys Ile
                 680                 685                 690

 Thr Lys Thr Arg Ser Met Met Ala Leu Leu Val Gln Leu Leu Ser
                 695                 700                 705

 Leu Cys Tyr Lys Leu Leu Lys Lys Leu Gln Met Glu Asn Asn Gly
                 710                 715                 720

 Trp Val Ser Val Thr Asn Lys Asp Thr Met Asp Ser Lys Thr
                 725                 730

<210> 607
<211> 4221
<212> DNA
<213> Homo sapien

<400> 607
 gtcggccgtc ccctttaatt tttaaataca cggtcccctc ttttctctgg 50

 ggggggcaag caagaaatca aagaaggagg agacaagccg tcaattttct 100

 ccaaaacaaa ccccaccggg caatttggtc tcggggtagg gggagacggg 150

 gtgattgcaa attattccag gacgagatcc agttctccag cgggaaaggg 200

 gcaaaggaac gccgcgcgtt ggaagggcca gggtacgcag ctccccttgc 250

 agcgcccgca ggacccccgc aagctcgtgc cggcgaaatc ggagaccgcc 300

 gatctgtcct cgttctctcc tgcacgtctg gctgcattcg gaggaagacc 350

 tggggcgcga gcgagcggcg acagcatgag cctgtgctga cctccgcgcg 400

 gcgggccgag cccagggctt tgtcgcggta cctgcgccca gcccgcgccg 450

 caactctgtg cccagctttt gcaatctttt gttgcagcgc tgaccgcacc 500

 aagttaaatg ctcccttgca atttttcttt tttttgtttg tttgtttaat 550

 ttttggagag ctcgcgatct tggaaaagcc tcagacgcca tctacagtta 600

 aaacgtaggt aactgccctc tcccgcaccc cccccttaca cgccccccac 650

 cctttccacc aaaaaaaggg ggtgcagcgc ggattctggc tgccgtgcgt 700

 cgccagccgg tagacccgtg cttgtttcct ttctcttttt gtttggcttc 750

 taacgcgttg ggactgagtc gccgccgtga gctccccgaa gactgcacaa 800

 actaccgcgg gctcctccgc cccgtctgcg attcggaagc cggcctgggg 850

 gtcgcgtcgg gagccctgcg ctgcagctcc gcaccttagc agcccgggta 900

 ctcatccaga tccacgccgg ggacacacac acagagtaac taaaagtgcg 950

 gcgattctgc acatcgccga ctgctttggg gtaacaaaaa gacccgagtt 1000

 gcctgccgac cgaggacccc cgggagccgg gctcggagca gacgaggtat 1050

 ccggcggcgc ccatttgggg gcttctaact ctttctccac gcagcccctc 1100

 ttctgtcccc tcccctctcg ctccctttta aaatcagtgg caccgaggcg 1150

 cctgcagccg cactcgccag cgactcatct ctccagcggg tttttttttg 1200

 tttgtcgtgt gcgatcctca cactcatgaa catacacagg tctaccccca 1250

 tcacaatagc gagatatggg agatcgcgga acaaaaccca ggatttcgaa 1300

 gagttgtcgt ctataaggtc cgcggagccc agccagagtt tcagcccgaa 1350

 cctcggctcc ccgagcccgc ccgagactcc gaacttgtcg cattgcgttt 1400

 cttgtatcgg gaaatactta ttgttggaac ctctggaggg agaccacgtt 1450

 tttcgtgccg tgcatctgca cagcggagag gagctggtgt gcaaggtgtt 1500

 tgatatcagc tgctaccagg aatccctggc accgtgcttt tgcctgtctg 1550

 ctcatagtaa catcaaccaa atcactgaaa ttatcctggg tgagaccaaa 1600

 gcctatgtgt tctttgagcg aagctatggg gacatgcatt ccttcgtccg 1650

 cacctgcaag aagctgagag aggaggaggc agccagactg ttctaccaga 1700

 ttgcctcggc agtggcccac tgccatgacg gggggctggt gctgcgggac 1750

 ctcaagctgc ggaaattcat ctttaaggac gaagagagga ctcgggtcaa 1800

 gctggaaagc ctggaagacg cctacattct gcggggagat gatgattccc 1850

 tctccgacaa gcatggctgc ccggcttacg taagcccaga gatcttgaac 1900

 accagtggca gctactcggg caaagcagcc gacgtgtgga gcctgggggt 1950

 gatgctgtac accatgttgg tggggcggta ccctttccat gacattgaac 2000

 ccagctccct cttcagcaag atccggcgtg gccagttcaa cattccagag 2050

 actctgtcgc ccaaggccaa gtgcctcatc cgaagcattc tgcgtcggga 2100

 gccctcagag cggctgacct cgcaggaaat tctggaccat ccttggtttt 2150

 ctacagattt tagcgtctcg aattcagcat atggtgctaa ggaagtgtct 2200

 gaccagctgg tgccggacgt caacatggaa gagaacttgg accctttctt 2250

 taactgagct catgccccac ggagacttag caggttccag gagtgagcga 2300

 gggcagcgga aaggagttct tccgggggac acgaattgcc tggctgagta 2350

 gcaagaaaga cacactctta agtttcttgg ttcagagcag gaaaaccttc 2400

 aaggagctga ctgaccacgt agcatggggg caagaggcgt gggatgggga 2450

 ttggggtgag atggatggga gcccgctgga gcttgtcttc cctaacatag 2500

 cctgggagac caccccttgc cacttgggcc acttccgcct accccacttt 2550

 tcattttgtt ccaaaatagt tgcagatcct gacagaatca aaactctctg 2600

 cctcaaacac acatcctggc atcgcactgt tagcatttaa cttcttgtta 2650

 ggattcaggg aaggaacagt tggccaagaa ttttttttct tttaaacaag 2700

 ccaaccacct agctggtaat taatgaggtt cacttaaaaa aaaaattcgg 2750

 tgcacacaga ctgacatgaa acctgggtgc tacagtaaaa gaaaacaaaa 2800

 gtccagtttg tgtctcttaa tcgctcactt caactcattt cttctaaata 2850

 aactatttaa tatcctggtc aggaaatgac atgttaatgc tttgctccct 2900

 gaagggggaa aaaatctgtc ctttaacaag ctattctgtt ttgtgtcaat 2950

 tgggtccgtg gcaaggaagc tattaggaag tcaaacggtc caggatgcat 3000

 tacctgctaa tccttaggtt taaaggggga aagaaaaggg aagaagaaag 3050

 gaaaagagaa atccaactcc tttttcatgt tttgcttttg aacaatgagg 3100

 gtttgtgtga caggcattcc tctttgctga gatgatagca atggcctgag 3150

 attttagcaa gctcctggag tctgatgctt ttgcagtact ctgatcgcaa 3200

 ctaaacattt gtctttgttt tattagaaac tagtgaaaca aagcaggttg 3250

 tcccacatgt ataaaataca gggcagctat ttagttttct ttacagagaa 3300

 tgatcctttt aaggcttgta aggccctctg gtttggacaa aaaccctcag 3350

 tagagacaag cgggaaggat aattagctga aagctatgat gatataaata 3400

 aaaacagctc tctatcccaa tacgcacctt tgtattttca agaactcttc 3450

 tatttattaa ggaaaatgtc acattgtgat gtattaagcc agtacttcaa 3500

 ttacgggttg acttgggatg acatattaca tgctgtagtt aacatttata 3550

 attctttttc cttgtttgag tatttctgtc tctgaaataa ccttttactt 3600

 ggcttttcta gatagcttta tttgatttcg agtggcaaaa tgttttttat 3650

 tacggctttt ctattgctgt atgatacaga actcttttgg cataaatatt 3700

 tgtgttccca gtacctcact tgttcggatt tgactgcctg tatatgtttt 3750

 gtgaaatggt cctgtttttg ggtaggtgac acgtggactc tagtatgtaa 3800

 atgttacttg aatctgtgct tcataatagt gtgtggcatg tatgtgcaga 3850

 ctcttggatg ctttatgcct gcgcaccagg agccctgtcc tcacgttccc 3900

 aggagggcgg cttcaccctt cgtaaccagg agacaaggcg gccatggatt 3950

 tgcccttgat tctattttgc taatggaaga tagaaaggag agaaggtttt 4000

 tttttttttt taacattctg aagatggtgc tgtgtcaaga aggacctttt 4050

 ttttcccctc tcccctattt tttaagtacc ttggaggagg agaggttggt 4100

 gacatgcatg gtggggatct atggcctctg gtgctttgtc ctgtatttgg 4150

 tttaatgttt ttgtcctaat ctcttcaatc aataaaattg tgcgtattta 4200

 actaaaaaaa aaaaaaaaaa a 4221

<210> 608
<211> 343
<212> PRT
<213> Homo sapien

<400> 608
 Met Asn Ile His Arg Ser Thr Pro Ile Thr Ile Ala Arg Tyr Gly
   1               5                  10                  15

 Arg Ser Arg Asn Lys Thr Gln Asp Phe Glu Glu Leu Ser Ser Ile
                  20                  25                  30

 Arg Ser Ala Glu Pro Ser Gln Ser Phe Ser Pro Asn Leu Gly Ser
                  35                  40                  45

 Pro Ser Pro Pro Glu Thr Pro Asn Leu Ser His Cys Val Ser Cys
                  50                  55                  60

 Ile Gly Lys Tyr Leu Leu Leu Glu Pro Leu Glu Gly Asp His Val
                  65                  70                  75

 Phe Arg Ala Val His Leu His Ser Gly Glu Glu Leu Val Cys Lys
                  80                  85                  90

 Val Phe Asp Ile Ser Cys Tyr Gln Glu Ser Leu Ala Pro Cys Phe
                  95                 100                 105

 Cys Leu Ser Ala His Ser Asn Ile Asn Gln Ile Thr Glu Ile Ile
                 110                 115                 120

 Leu Gly Glu Thr Lys Ala Tyr Val Phe Phe Glu Arg Ser Tyr Gly
                 125                 130                 135

 Asp Met His Ser Phe Val Arg Thr Cys Lys Lys Leu Arg Glu Glu
                 140                 145                 150

 Glu Ala Ala Arg Leu Phe Tyr Gln Ile Ala Ser Ala Val Ala His
                 155                 160                 165

 Cys His Asp Gly Gly Leu Val Leu Arg Asp Leu Lys Leu Arg Lys
                 170                 175                 180

 Phe Ile Phe Lys Asp Glu Glu Arg Thr Arg Val Lys Leu Glu Ser
                 185                 190                 195

 Leu Glu Asp Ala Tyr Ile Leu Arg Gly Asp Asp Asp Ser Leu Ser
                 200                 205                 210

 Asp Lys His Gly Cys Pro Ala Tyr Val Ser Pro Glu Ile Leu Asn
                 215                 220                 225

 Thr Ser Gly Ser Tyr Ser Gly Lys Ala Ala Asp Val Trp Ser Leu
                 230                 235                 240

 Gly Val Met Leu Tyr Thr Met Leu Val Gly Arg Tyr Pro Phe His
                 245                 250                 255

 Asp Ile Glu Pro Ser Ser Leu Phe Ser Lys Ile Arg Arg Gly Gln
                 260                 265                 270

 Phe Asn Ile Pro Glu Thr Leu Ser Pro Lys Ala Lys Cys Leu Ile
                 275                 280                 285

 Arg Ser Ile Leu Arg Arg Glu Pro Ser Glu Arg Leu Thr Ser Gln
                 290                 295                 300

 Glu Ile Leu Asp His Pro Trp Phe Ser Thr Asp Phe Ser Val Ser
                 305                 310                 315

 Asn Ser Ala Tyr Gly Ala Lys Glu Val Ser Asp Gln Leu Val Pro
                 320                 325                 330

 Asp Val Asn Met Glu Glu Asn Leu Asp Pro Phe Phe Asn
                 335                 340

<210> 609
<211> 4221
<212> DNA
<213> Homo sapien

<400> 609
 gtcggccgtc ccctttaatt tttaaataca cggtcccctc ttttctctgg 50

 ggggggcaag caagaaatca aagaaggagg agacaagccg tcaattttct 100

 ccaaaacaaa ccccaccggg caatttggtc tcggggtagg gggagacggg 150

 gtgattgcaa attattccag gacgagatcc agttctccag cgggaaaggg 200

 gcaaaggaac gccgcgcgtt ggaagggcca gggtacgcag ctccccttgc 250

 agcgcccgca ggacccccgc aagctcgtgc cggcgaaatc ggagaccgcc 300

 gatctgtcct cgttctctcc tgcacgtctg gctgcattcg gaggaagacc 350

 tggggcgcga gcgagcggcg acagcatgag cctgtgctga cctccgcgcg 400

 gcgggccgag cccagggctt tgtcgcggta cctgcgccca gcccgcgccg 450

 caactctgtg cccagctttt gcaatctttt gttgcagcgc tgaccgcacc 500

 aagttaaatg ctcccttgca atttttcttt tttttgtttg tttgtttaat 550

 ttttggagag ctcgcgatct tggaaaagcc tcagacgcca tctacagtta 600

 aaacgtaggt aactgccctc tcccgcaccc cccccttaca cgccccccac 650

 cctttccacc aaaaaaaggg ggtgcagcgc ggattctggc tgccgtgcgt 700

 cgccagccgg tagacccgtg cttgtttcct ttctcttttt gtttggcttc 750

 taacgcgttg ggactgagtc gccgccgtga gctccccgaa gactgcacaa 800

 actaccgcgg gctcctccgc cccgtctgcg attcggaagc cggcctgggg 850

 gtcgcgtcgg gagccctgcg ctgcagctcc gcaccttagc agcccgggta 900

 ctcatccaga tccacgccgg ggacacacac acagagtaac taaaagtgcg 950

 gcgattctgc acatcgccga ctgctttggg gtaacaaaaa gacccgagtt 1000

 gcctgccgac cgaggacccc cgggagccgg gctcggagca gacgaggtat 1050

 ccggcggcgc ccatttgggg gcttctaact ctttctccac gcagcccctc 1100

 ttctgtcccc tcccctctcg ctccctttta aaatcagtgg caccgaggcg 1150

 cctgcagccg cactcgccag cgactcatct ctccagcggg tttttttttg 1200

 tttgtcgtgt gcgatcctca cactcatgaa catacacagg tctaccccca 1250

 tcacaatagc gagatatggg agatcgcgga acaaaaccca ggatttcgaa 1300

 gagttgtcgt ctataaggtc cgcggagccc agccagagtt tcagcccgaa 1350

 cctcggctcc ccgagcccgc ccgagactcc gaacttgtcg cattgcgttt 1400

 cttgtatcgg gaaatactta ttgttggaac ctctggaggg agaccacgtt 1450

 tttcgtgccg tgcatctgca cagcggagag gagctggtgt gcaaggtgtt 1500

 tgatatcagc tgctaccagg aatccctggc accgtgcttt tgcctgtctg 1550

 ctcatagtaa catcaaccaa atcactgaaa ttatcctggg tgagaccaaa 1600

 gcctatgtgt tctttgagcg aagctatggg gacatgcatt ccttcgtccg 1650

 cacctgcaag aagctgagag aggaggaggc agccagactg ttctaccaga 1700

 ttgcctcggc agtggcccac tgccatgacg gggggctggt gctgcgggac 1750

 ctcaagctgc ggaaattcat ctttaaggac gaagagagga ctcgggtcaa 1800

 gctggaaagc ctggaagacg cctacattct gcggggagat gatgattccc 1850

 tctccgacaa gcatggctgc ccggcttacg taagcccaga gatcttgaac 1900

 accagtggca gctactcggg caaagcagcc gacgtgtgga gcctgggggt 1950

 gatgctgtac accatgttgg tggggcggta ccctttccat gacattgaac 2000

 ccagctccct cttcagcaag atccggcgtg gccagttcaa cattccagag 2050

 actctgtcgc ccaaggccaa gtgcctcatc cgaagcattc tgcgtcggga 2100

 gccctcagag cggctgacct cgcaggaaat tctggaccat ccttggtttt 2150

 ctacagattt tagcgtctcg aattcagcat atggtgctaa ggaagtgtct 2200

 gaccagctgg tgccggacgt caacatggaa gagaacttgg accctttctt 2250

 taactgagct catgccccac ggagacttag caggttccag gagtgagcga 2300

 gggcagcgga aaggagttct tccgggggac acgaattgcc tggctgagta 2350

 gcaagaaaga cacactctta agtttcttgg ttcagagcag gaaaaccttc 2400

 aaggagctga ctgaccacgt agcatggggg caagaggcgt gggatgggga 2450

 ttggggtgag atggatggga gcccgctgga gcttgtcttc cctaacatag 2500

 cctgggagac caccccttgc cacttgggcc acttccgcct accccacttt 2550

 tcattttgtt ccaaaatagt tgcagatcct gacagaatca aaactctctg 2600

 cctcaaacac acatcctggc atcgcactgt tagcatttaa cttcttgtta 2650

 ggattcaggg aaggaacagt tggccaagaa ttttttttct tttaaacaag 2700

 ccaaccacct agctggtaat taatgaggtt cacttaaaaa aaaaattcgg 2750

 tgcacacaga ctgacatgaa acctgggtgc tacagtaaaa gaaaacaaaa 2800

 gtccagtttg tgtctcttaa tcgctcactt caactcattt cttctaaata 2850

 aactatttaa tatcctggtc aggaaatgac atgttaatgc tttgctccct 2900

 gaagggggaa aaaatctgtc ctttaacaag ctattctgtt ttgtgtcaat 2950

 tgggtccgtg gcaaggaagc tattaggaag tcaaacggtc caggatgcat 3000

 tacctgctaa tccttaggtt taaaggggga aagaaaaggg aagaagaaag 3050

 gaaaagagaa atccaactcc tttttcatgt tttgcttttg aacaatgagg 3100

 gtttgtgtga caggcattcc tctttgctga gatgatagca atggcctgag 3150

 attttagcaa gctcctggag tctgatgctt ttgcagtact ctgatcgcaa 3200

 ctaaacattt gtctttgttt tattagaaac tagtgaaaca aagcaggttg 3250

 tcccacatgt ataaaataca gggcagctat ttagttttct ttacagagaa 3300

 tgatcctttt aaggcttgta aggccctctg gtttggacaa aaaccctcag 3350

 tagagacaag cgggaaggat aattagctga aagctatgat gatataaata 3400

 aaaacagctc tctatcccaa tacgcacctt tgtattttca agaactcttc 3450

 tatttattaa ggaaaatgtc acattgtgat gtattaagcc agtacttcaa 3500

 ttacgggttg acttgggatg acatattaca tgctgtagtt aacatttata 3550

 attctttttc cttgtttgag tatttctgtc tctgaaataa ccttttactt 3600

 ggcttttcta gatagcttta tttgatttcg agtggcaaaa tgttttttat 3650

 tacggctttt ctattgctgt atgatacaga actcttttgg cataaatatt 3700

 tgtgttccca gtacctcact tgttcggatt tgactgcctg tatatgtttt 3750

 gtgaaatggt cctgtttttg ggtaggtgac acgtggactc tagtatgtaa 3800

 atgttacttg aatctgtgct tcataatagt gtgtggcatg tatgtgcaga 3850

 ctcttggatg ctttatgcct gcgcaccagg agccctgtcc tcacgttccc 3900

 aggagggcgg cttcaccctt cgtaaccagg agacaaggcg gccatggatt 3950

 tgcccttgat tctattttgc taatggaaga tagaaaggag agaaggtttt 4000

 tttttttttt taacattctg aagatggtgc tgtgtcaaga aggacctttt 4050

 ttttcccctc tcccctattt tttaagtacc ttggaggagg agaggttggt 4100

 gacatgcatg gtggggatct atggcctctg gtgctttgtc ctgtatttgg 4150

 tttaatgttt ttgtcctaat ctcttcaatc aataaaattg tgcgtattta 4200

 actaaaaaaa aaaaaaaaaa a 4221

<210> 610
<211> 343
<212> PRT
<213> Homo sapien

<400> 610
 Met Asn Ile His Arg Ser Thr Pro Ile Thr Ile Ala Arg Tyr Gly
   1               5                  10                  15

 Arg Ser Arg Asn Lys Thr Gln Asp Phe Glu Glu Leu Ser Ser Ile
                  20                  25                  30

 Arg Ser Ala Glu Pro Ser Gln Ser Phe Ser Pro Asn Leu Gly Ser
                  35                  40                  45

 Pro Ser Pro Pro Glu Thr Pro Asn Leu Ser His Cys Val Ser Cys
                  50                  55                  60

 Ile Gly Lys Tyr Leu Leu Leu Glu Pro Leu Glu Gly Asp His Val
                  65                  70                  75

 Phe Arg Ala Val His Leu His Ser Gly Glu Glu Leu Val Cys Lys
                  80                  85                  90

 Val Phe Asp Ile Ser Cys Tyr Gln Glu Ser Leu Ala Pro Cys Phe
                  95                 100                 105

 Cys Leu Ser Ala His Ser Asn Ile Asn Gln Ile Thr Glu Ile Ile
                 110                 115                 120

 Leu Gly Glu Thr Lys Ala Tyr Val Phe Phe Glu Arg Ser Tyr Gly
                 125                 130                 135

 Asp Met His Ser Phe Val Arg Thr Cys Lys Lys Leu Arg Glu Glu
                 140                 145                 150

 Glu Ala Ala Arg Leu Phe Tyr Gln Ile Ala Ser Ala Val Ala His
                 155                 160                 165

 Cys His Asp Gly Gly Leu Val Leu Arg Asp Leu Lys Leu Arg Lys
                 170                 175                 180

 Phe Ile Phe Lys Asp Glu Glu Arg Thr Arg Val Lys Leu Glu Ser
                 185                 190                 195

 Leu Glu Asp Ala Tyr Ile Leu Arg Gly Asp Asp Asp Ser Leu Ser
                 200                 205                 210

 Asp Lys His Gly Cys Pro Ala Tyr Val Ser Pro Glu Ile Leu Asn
                 215                 220                 225

 Thr Ser Gly Ser Tyr Ser Gly Lys Ala Ala Asp Val Trp Ser Leu
                 230                 235                 240

 Gly Val Met Leu Tyr Thr Met Leu Val Gly Arg Tyr Pro Phe His
                 245                 250                 255

 Asp Ile Glu Pro Ser Ser Leu Phe Ser Lys Ile Arg Arg Gly Gln
                 260                 265                 270

 Phe Asn Ile Pro Glu Thr Leu Ser Pro Lys Ala Lys Cys Leu Ile
                 275                 280                 285

 Arg Ser Ile Leu Arg Arg Glu Pro Ser Glu Arg Leu Thr Ser Gln
                 290                 295                 300

 Glu Ile Leu Asp His Pro Trp Phe Ser Thr Asp Phe Ser Val Ser
                 305                 310                 315

 Asn Ser Ala Tyr Gly Ala Lys Glu Val Ser Asp Gln Leu Val Pro
                 320                 325                 330

 Asp Val Asn Met Glu Glu Asn Leu Asp Pro Phe Phe Asn
                 335                 340

<210> 611
<211> 884
<212> DNA
<213> Homo sapien

<400> 611
 cgaggttcgg gtcgtggggc ggagggaaga gcgggcgggc gggaggcgcc 50

 ggcgccagac gcggagggaa ggagctacga gtagccgccg agaggccgcg 100

 gagccagcga cgaccgaccc agccgagccg ccgccgccgc cgcgccccca 150

 tggcggccgc caaggacact catgaggacc atgatacttc cactgagaat 200

 acagacgagt ccaaccatga ccctcagttt gagccaatag tttctcttcc 250

 tgagcaagaa attaaaacac tggaagaaga tgaagaggaa ctttttaaaa 300

 tgcgggcaaa actgttccga tttgcctctg agaacgatct cccagaatgg 350

 aaggagcgag gcactggtga cgtcaagctc ctgaagcaca aggagaaagg 400

 ggccatccgc ctcctcatgc ggagggacaa gaccctgaag atctgtgcca 450

 accactacat cacgccgatg atggagctga agcccaacgc aggtagcgac 500

 cgtgcctggg tctggaacac ccacgctgac ttcgccgacg agtgccccaa 550

 gccagagctg ctggccatcc gcttcctgaa tgctgagaat gcacagaaat 600

 tcaaaacaaa gtttgaagaa tgcaggaaag agatcgaaga gagagaaaag 650

 aaagcaggat caggcaaaaa tgatcatgcc gaaaaagtgg cggaaaagct 700

 agaagctctc tcggtgaagg aggagaccaa ggaggatgct gaggagaagc 750

 aataaatcgt cttattttat tttcttttcc tctctttcct ttcctttttt 800

 taaaaaattt taccctgccc ctctttttcg gtttgttttt attctttcat 850

 ttttacaagg gacgttatat aaagaactga actc 884

<210> 612
<211> 201
<212> PRT
<213> Homo sapien

<400> 612
 Met Ala Ala Ala Lys Asp Thr His Glu Asp His Asp Thr Ser Thr
   1               5                  10                  15

 Glu Asn Thr Asp Glu Ser Asn His Asp Pro Gln Phe Glu Pro Ile
                  20                  25                  30

 Val Ser Leu Pro Glu Gln Glu Ile Lys Thr Leu Glu Glu Asp Glu
                  35                  40                  45

 Glu Glu Leu Phe Lys Met Arg Ala Lys Leu Phe Arg Phe Ala Ser
                  50                  55                  60

 Glu Asn Asp Leu Pro Glu Trp Lys Glu Arg Gly Thr Gly Asp Val
                  65                  70                  75

 Lys Leu Leu Lys His Lys Glu Lys Gly Ala Ile Arg Leu Leu Met
                  80                  85                  90

 Arg Arg Asp Lys Thr Leu Lys Ile Cys Ala Asn His Tyr Ile Thr
                  95                 100                 105

 Pro Met Met Glu Leu Lys Pro Asn Ala Gly Ser Asp Arg Ala Trp
                 110                 115                 120

 Val Trp Asn Thr His Ala Asp Phe Ala Asp Glu Cys Pro Lys Pro
                 125                 130                 135

 Glu Leu Leu Ala Ile Arg Phe Leu Asn Ala Glu Asn Ala Gln Lys
                 140                 145                 150

 Phe Lys Thr Lys Phe Glu Glu Cys Arg Lys Glu Ile Glu Glu Arg
                 155                 160                 165

 Glu Lys Lys Ala Gly Ser Gly Lys Asn Asp His Ala Glu Lys Val
                 170                 175                 180

 Ala Glu Lys Leu Glu Ala Leu Ser Val Lys Glu Glu Thr Lys Glu
                 185                 190                 195

 Asp Ala Glu Glu Lys Gln
                 200

<210> 613
<211> 2584
<212> DNA
<213> Homo sapien

<400> 613
 gggggcgtgg ccccgagaag gcggagacaa gatggccgcc catagcgctt 50

 ggaggaccta agaggcggtg gccggggcca cgccccgggc aggagggccg 100

 ctctgtgcgc gcccgctcta tgatgcttgc gcgcgtcccc cgcgcgccgc 150

 gctgcgggcg gggcgggtct ccgggattcc aagggctcgg ttacggaaga 200

 agcgcagcgc cggctgggga gggggctgga tgcgcgcgca cccgggggga 250

 ggccgctgct gcccggagca ggaggagggg gagagtgcgg cgggcggcag 300

 cggcgctggc ggcgactccg ccatagagca ggggggccag ggcagcgcgc 350

 tcgccccgtc cccggtgagc ggcgtgcgca gggaaggcgc tcggggcggc 400

 ggccgtggcc gggggcggtg gaagcaggcg ggccggggcg gcggcgtctg 450

 tggccgtggc cggggccggg gccgtggccg gggacgggga cggggccggg 500

 gccggggccg cggccgtccc ccgagtggcg gcagcggcct tggcggcgac 550

 ggcggcggct gcggcggcgg cggcagcggt ggcggcggcg ccccccggcg 600

 ggagccggtc cctttcccgt cggggagcgc ggggccgggg cccaggggac 650

 cccgggccac ggagagcggg aagaggatgg attgcccggc cctccccccc 700

 ggatggaaga aggaggaagt gatccgaaaa tctgggctaa gtgctggcaa 750

 gagcgatgtc tactacttca gtccaagtgg taagaagttc agaagcaagc 800

 ctcagttggc aaggtacctg ggaaatactg ttgatctcag cagttttgac 850

 ttcagaactg gaaagatgat gcctagtaaa ttacagaaga acaaacagag 900

 actgcgaaac gatcctctca atcaaaataa gggtaaacca gacttgaata 950

 caacattgcc aattagacaa acagcatcaa ttttcaaaca accggtaacc 1000

 aaagtcacaa atcatcctag taataaagtg aaatcagacc cacaacgaat 1050

 gaatgaacag ccacgtcagc ttttctggga gaagaggcta caaggactta 1100

 gtgcatcaga tgtaacagaa caaattataa aaaccatgga actacccaaa 1150

 ggtcttcaag gagttggtcc aggtagcaat gatgagaccc ttttatctgc 1200

 tgttgccagt gctttgcaca caagctctgc gccaatcaca gggcaagtct 1250

 ccgctgctgt ggaaaagaac cctgctgttt ggcttaacac atctcaaccc 1300

 ctctgcaaag cttttattgt cacagatgaa gacatcagga aacaggaaga 1350

 gcgagtacag caagtacgca agaaattgga agaagcactg atggcagaca 1400

 tcttgtcgcg agctgctgat acagaagaga tggatattga aatggacagt 1450

 ggagatgaag cctaagaata tgatcaggta actttcgacc gactttcccc 1500

 aagagaaaat tcctagaaat tgaacaaaaa tgtttccact ggcttttgcc 1550

 tgtaagaaaa aaaatgtacc cgagcacata gagcttttta atagcactaa 1600

 ccaatgcctt tttagatgta tttttgatgt atatatctat tattcaaaaa 1650

 atcatgttta ttttgagtcc taggacttaa aattagtctt ttgtaatatc 1700

 aagcaggacc ctaagatgaa gctgagcttt tgatgccagg tgcaatctac 1750

 tggaaatgta gcacttacgt aaaacatttg tttcccccac agttttaata 1800

 agaacagatc aggaattcta aataaatttc ccagttaaag attattgtga 1850

 cttcactgta tataaacata tttttatact ttattgaaag gggacacctg 1900

 tacattcttc catcatcact gtaaagacaa ataaatgatt atattcacag 1950

 actgattgga attctttctg ttgaaaagca cacacaataa agaacccctc 2000

 gttagccttc ctctgattta cattcaactc tgatccctgg gccttaggtt 2050

 tgacatggag gtggaggaag atagcgcata tatttgcagt atgaactatt 2100

 gcctctggac gttgtgagaa ttgtgctttc accagaattt ctaagaattt 2150

 ctgctaaata tcacctagca tgtgtaattt tttttccttg cctgtgactt 2200

 ggacttttga tagttctata agaataaggc tttttcttcc cttgggcatg 2250

 agtcagatac acaaggaccc ttcaggtgtt actagaaggc gtccatgttt 2300

 attgtttttt aaagaatgtt tggcactctc taacgtccac tagcttactg 2350

 agttatcagg tgcaggtcag actcttggct acagtgagag gcagcttcta 2400

 ggcagagttg cttaatgaaa gggtttgtaa tactttacaa accattacct 2450

 gtacctggcc tggcctccaa aatattaaca ttctttttct gttgaaactc 2500

 gcgagtgtaa ctttcatacc acttgaattt attgatattt aattatgaaa 2550

 actagcatta cattattaaa cgatttctaa aatc 2584

<210> 614
<211> 411
<212> PRT
<213> Homo sapien

<400> 614
 Met Arg Ala His Pro Gly Gly Gly Arg Cys Cys Pro Glu Gln Glu
   1               5                  10                  15

 Glu Gly Glu Ser Ala Ala Gly Gly Ser Gly Ala Gly Gly Asp Ser
                  20                  25                  30

 Ala Ile Glu Gln Gly Gly Gln Gly Ser Ala Leu Ala Pro Ser Pro
                  35                  40                  45

 Val Ser Gly Val Arg Arg Glu Gly Ala Arg Gly Gly Gly Arg Gly
                  50                  55                  60

 Arg Gly Arg Trp Lys Gln Ala Gly Arg Gly Gly Gly Val Cys Gly
                  65                  70                  75

 Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg
                  80                  85                  90

 Gly Arg Gly Arg Gly Arg Pro Pro Ser Gly Gly Ser Gly Leu Gly
                  95                 100                 105

 Gly Asp Gly Gly Gly Cys Gly Gly Gly Gly Ser Gly Gly Gly Gly
                 110                 115                 120

 Ala Pro Arg Arg Glu Pro Val Pro Phe Pro Ser Gly Ser Ala Gly
                 125                 130                 135

 Pro Gly Pro Arg Gly Pro Arg Ala Thr Glu Ser Gly Lys Arg Met
                 140                 145                 150

 Asp Cys Pro Ala Leu Pro Pro Gly Trp Lys Lys Glu Glu Val Ile
                 155                 160                 165

 Arg Lys Ser Gly Leu Ser Ala Gly Lys Ser Asp Val Tyr Tyr Phe
                 170                 175                 180

 Ser Pro Ser Gly Lys Lys Phe Arg Ser Lys Pro Gln Leu Ala Arg
                 185                 190                 195

 Tyr Leu Gly Asn Thr Val Asp Leu Ser Ser Phe Asp Phe Arg Thr
                 200                 205                 210

 Gly Lys Met Met Pro Ser Lys Leu Gln Lys Asn Lys Gln Arg Leu
                 215                 220                 225

 Arg Asn Asp Pro Leu Asn Gln Asn Lys Gly Lys Pro Asp Leu Asn
                 230                 235                 240

 Thr Thr Leu Pro Ile Arg Gln Thr Ala Ser Ile Phe Lys Gln Pro
                 245                 250                 255

 Val Thr Lys Val Thr Asn His Pro Ser Asn Lys Val Lys Ser Asp
                 260                 265                 270

 Pro Gln Arg Met Asn Glu Gln Pro Arg Gln Leu Phe Trp Glu Lys
                 275                 280                 285

 Arg Leu Gln Gly Leu Ser Ala Ser Asp Val Thr Glu Gln Ile Ile
                 290                 295                 300

 Lys Thr Met Glu Leu Pro Lys Gly Leu Gln Gly Val Gly Pro Gly
                 305                 310                 315

 Ser Asn Asp Glu Thr Leu Leu Ser Ala Val Ala Ser Ala Leu His
                 320                 325                 330

 Thr Ser Ser Ala Pro Ile Thr Gly Gln Val Ser Ala Ala Val Glu
                 335                 340                 345

 Lys Asn Pro Ala Val Trp Leu Asn Thr Ser Gln Pro Leu Cys Lys
                 350                 355                 360

 Ala Phe Ile Val Thr Asp Glu Asp Ile Arg Lys Gln Glu Glu Arg
                 365                 370                 375

 Val Gln Gln Val Arg Lys Lys Leu Glu Glu Ala Leu Met Ala Asp
                 380                 385                 390

 Ile Leu Ser Arg Ala Ala Asp Thr Glu Glu Met Asp Ile Glu Met
                 395                 400                 405

 Asp Ser Gly Asp Glu Ala
                 410

<210> 615
<211> 847
<212> DNA
<213> Homo sapien

<400> 615
 tggggttcga accagcaaga caagcgggca ttggccacag cagcgcgagg 50

 cgggcacggg gtattgtccg gctccggcgg cggcggtcgg tgctgcgaga 100

 gcggcggcgg cggcgcgggt cggcagcggg agggcgcgcg gccgagcgga 150

 ggcggagtcg gcgccgagaa catggctgga ggcaaagctg gaaaggacag 200

 tgggaaggcc aaggctaagg cagtatctcg ctcacagaga gctgggctac 250

 agtttcctgt gggccgcatc cacagacact tgaagactcg caccacaagc 300

 catggaaggg tgggtgccac tgctgccgtg tacagtgctg cgattctgga 350

 gtacctcact gcagaggtgc tggagctggc aggtaatgct tctaaggatc 400

 tcaaagtaaa gcgtatcact ccgcgtcact tgcagcttgc aatccgtggt 450

 gatgaagagt tggattctct tatcaaggct accatagctg ggggtggtgt 500

 gatccctcac atccacaaat ctctgattgg aaagaaggga cagcagaaaa 550

 ctgcttagag ggatgcttta accaaccctc ttcctccccg tcattgtact 600

 gtaactggga cagaagaaat aatggggata tgtggaattt ttaacaacag 650

 ttaaatggaa aagcatagac aattactgta gacatgataa aagaaacatt 700

 tgtatgttct tagactcgaa gtttgataaa agtacctttt catgtggtga 750

 cagttgtgtg ttgattggct aggtttctcc cgtgtgtttt atacaaaaat 800

 ggaattgata aaccattttt tacaaaatta aaaaaaaaaa aaaaaaa 847

<210> 616
<211> 128
<212> PRT
<213> Homo sapien

<400> 616
 Met Ala Gly Gly Lys Ala Gly Lys Asp Ser Gly Lys Ala Lys Ala
   1               5                  10                  15

 Lys Ala Val Ser Arg Ser Gln Arg Ala Gly Leu Gln Phe Pro Val
                  20                  25                  30

 Gly Arg Ile His Arg His Leu Lys Thr Arg Thr Thr Ser His Gly
                  35                  40                  45

 Arg Val Gly Ala Thr Ala Ala Val Tyr Ser Ala Ala Ile Leu Glu
                  50                  55                  60

 Tyr Leu Thr Ala Glu Val Leu Glu Leu Ala Gly Asn Ala Ser Lys
                  65                  70                  75

 Asp Leu Lys Val Lys Arg Ile Thr Pro Arg His Leu Gln Leu Ala
                  80                  85                  90

 Ile Arg Gly Asp Glu Glu Leu Asp Ser Leu Ile Lys Ala Thr Ile
                  95                 100                 105

 Ala Gly Gly Gly Val Ile Pro His Ile His Lys Ser Leu Ile Gly
                 110                 115                 120

 Lys Lys Gly Gln Gln Lys Thr Ala
                 125

<210> 617
<211> 3915
<212> DNA
<213> Homo sapien

<400> 617
 gtggggtggg gtggggctgg gggcttgtcg ccctttcagg ctccaccctt 50

 tgcggagatt ataaatagtc atgatcccag cgagacccag agatgcctgt 100

 aatggtgaga ctttggatcc ttcctgagga cgtggagaaa actttctgct 150

 gagaaggaca ttttgaaggt tttgttggct gaaaaagctg tttctggaat 200

 cacccctaga tctttcttga agacttgaat tagattacag cgatggggac 250

 acagaaggtc accccagctc tgatatttgc catcacagtt gctacaatcg 300

 gctctttcca atttggctac aacactgggg tcatcaatgc tcctgagaag 350

 atcataaagg aatttatcaa taaaactttg acggacaagg gaaatgcccc 400

 accctctgag gtgctgctca cgtctctctg gtccttgtct gtggccatat 450

 tttccgtcgg gggtatgatc ggctcctttt ccgtcggact cttcgtcaac 500

 cgctttggca ggcgcaattc aatgctgatt gtcaacctgt tggctgtcac 550

 tggtggctgc tttatgggac tgtgtaaagt agctaagtcg gttgaaatgc 600

 tgatcctggg tcgcttggtt attggcctct tctgcggact ctgcacaggt 650

 tttgtgccca tgtacattgg agagatctcg cctactgccc tgcggggtgc 700

 ctttggcact ctcaaccagc tgggcatcgt tgttggaatt ctggtggccc 750

 agatctttgg tctggaattc atccttgggt ctgaagagct atggccgctg 800

 ctactgggtt ttaccatcct tcctgctatc ctacaaagtg cagcccttcc 850

 attttgccct gaaagtccca gatttttgct cattaacaga aaagaagagg 900

 agaatgctaa gcagatcctc cagcggttgt ggggcaccca ggatgtatcc 950

 caagacatcc aggagatgaa agatgagagt gcaaggatgt cacaagaaaa 1000

 gcaagtcacc gtgctagagc tctttagagt gtccagctac cgacagccca 1050

 tcatcatttc cattgtgctc cagctctctc agcagctctc tgggatcaat 1100

 gctgtgttct attactcaac aggaatcttc aaggatgcag gtgttcaaga 1150

 gcccatctat gccaccatcg gcgcgggtgt ggttaatact atcttcactg 1200

 tagtttctct atttctggtg gaaagggcag gaagaaggac tctgcatatg 1250

 ataggccttg gagggatggc tttttgttcc acgctcatga ctgtttcttt 1300

 gttattaaag gataactata atgggatgag ctttgtctgt attggggcta 1350

 tcttggtctt tgtagccttc tttgaaattg gaccaggccc cattccctgg 1400

 tttattgtgg ccgaactctt cagccagggc ccccgcccag ctgcgatggc 1450

 agtggccggc tgctccaact ggacctccaa cttcctagtc ggattgctct 1500

 tcccctccgc tgctcactat ttaggagcct acgtttttat tatcttcacc 1550

 ggcttcctca ttaccttctt ggcttttacc ttcttcaaag tccctgagac 1600

 ccgtggcagg acttttgagg atatcacacg ggcctttgaa gggcaggcac 1650

 acggtgcaga tagatctgga aaggacggcg tcatggagat gaacagcatc 1700

 gagcctgcta aggagaccac caccaatgtc taagtcgtgc ctccttccac 1750

 ctccctcccg gcatgggaaa gccacctctc cctcaacaag ggagagacct 1800

 catcaggatg aacccaggac gcttctgaat gctgctactt aattcctttc 1850

 tcatcccacg cactccatga gcaccccaag gctgcggttt gttggatctt 1900

 caatggcttt ttaaatttta tttcctggac atcctcttct gcttaggaga 1950

 gaccgagtga acctaccttc atttcaggag ggattggccg cttggcacat 2000

 gacaactttg ccagcttttc ctcccttggg ttctgatatt gccgcactag 2050

 gggatatagg agaggaaaag taaggtgcag ttcccccaac ctcagactta 2100

 ccaggaagca gatacatatg agtgtggaag ccggagggtg tttatgtaag 2150

 agcaccttcc tcacttccat acagctctac gtggcaaatt aacttgagtt 2200

 ttatttattt tatcctctgg tttaattaca taattttttt ttttttactt 2250

 taagtttcag gatacatgtg ccgaatgtgc aggtttgtta cataggtata 2300

 tatatgccat gatggaaata tttatttttt taagcgtaat tttgccaaat 2350

 aataaaaaca gaaggaaatt gagattagag ggaggtgttt aaagagaggt 2400

 tatagagtag aagatttgat gctggagagg ttaaggtgca ataagaattt 2450

 agggagaaat gttgttcatt attggagggt aaatgatgtg gtgcctgagg 2500

 tctgtacgtt acctcttaac aatttctgtc cttcagatgg aaactcttta 2550

 acttctcgta aaagtcatat acctatataa taaagctact gatttccttg 2600

 gagctttttt ctttaagata atagtttaca tgtagtagta cttgaaatct 2650

 aggattatta actaatatgg gcattgtagt taatgatggt tgatgggttc 2700

 taattttgga tggagtccag ggaagagaaa gtgatttcta gaaagcctgt 2750

 tcccctcact ggatgaaata actccttctt gtagtagtct cattactttt 2800

 gaagtaatcc cgccacctat ctcgtgggag agccatccaa ataagaaacc 2850

 taaaataatt ggttcttggt agagattcat tatttttcca ctttgttctt 2900

 taggagattt taggtgttga ttttctgttg tattttaact cataccttta 2950

 aaggaattcc ccaaagaatg tttatagcaa acttggaatt tgtaacctca 3000

 gctctgggag aggatttttt tctgagcgat tattatctaa agtgtgttgt 3050

 tgctttaggc tcacggcacg cttgcgtatg tctgttacca tgtcactgtg 3100

 gtcctatgcc gaatgccctc aggggacttg aatctttcca ataaaccagg 3150

 tttagacagt atgagtcaat gtgcagtgta gcccacactt gagaggatga 3200

 atgtatgtgc actgtcactt tgctctgggt ggaagtacgt tattgttgac 3250

 ttattttctc tgtgtttgtt cctacagccc ctttttcata tgttgctcag 3300

 tctccctttc ccttcttggt gcttacacat ctcagaccct ttagccaaac 3350

 ccttgtcagt gacagtattt tggttcttag ttctcactgt tccctctgct 3400

 cctggagcct ttgaataaaa atgcacgtag ctgaggccgg atgcggtggc 3450

 tcacgcctgt aatcccagca ctttgggagg cctaggcggg cggtcagggg 3500

 ttcgagacca gtctggccaa catcgtgaaa ccctgtctct actaaaaatg 3550

 caaaaattag ccgggcgtgg tggcgggcgc ctgtaatccc agctacttgg 3600

 gaagctgagg cgggagaatc atgtgaaccc gggacgcagg ggttgcagtg 3650

 agcggagatc gcatcattgc actctagcct gggccacagg gcgagactcc 3700

 gtctcaaaaa aaaaaaaatg cacatagcta tcgagtgtgc tttagcttga 3750

 aaaggtgacc ttgcaacttc atgtcaactt tctggctcct caaacagtag 3800

 gttggcagta aggcagggtc ccatttctca ctgagaagat tgtgaatatt 3850

 tccatatgga ttttctattg ttactctggt tctttgtttt aaaataaaaa 3900

 ttctgaatgt acacg 3915

<210> 618
<211> 496
<212> PRT
<213> Homo sapien

<400> 618
 Met Gly Thr Gln Lys Val Thr Pro Ala Leu Ile Phe Ala Ile Thr
   1               5                  10                  15

 Val Ala Thr Ile Gly Ser Phe Gln Phe Gly Tyr Asn Thr Gly Val
                  20                  25                  30

 Ile Asn Ala Pro Glu Lys Ile Ile Lys Glu Phe Ile Asn Lys Thr
                  35                  40                  45

 Leu Thr Asp Lys Gly Asn Ala Pro Pro Ser Glu Val Leu Leu Thr
                  50                  55                  60

 Ser Leu Trp Ser Leu Ser Val Ala Ile Phe Ser Val Gly Gly Met
                  65                  70                  75

 Ile Gly Ser Phe Ser Val Gly Leu Phe Val Asn Arg Phe Gly Arg
                  80                  85                  90

 Arg Asn Ser Met Leu Ile Val Asn Leu Leu Ala Val Thr Gly Gly
                  95                 100                 105

 Cys Phe Met Gly Leu Cys Lys Val Ala Lys Ser Val Glu Met Leu
                 110                 115                 120

 Ile Leu Gly Arg Leu Val Ile Gly Leu Phe Cys Gly Leu Cys Thr
                 125                 130                 135

 Gly Phe Val Pro Met Tyr Ile Gly Glu Ile Ser Pro Thr Ala Leu
                 140                 145                 150

 Arg Gly Ala Phe Gly Thr Leu Asn Gln Leu Gly Ile Val Val Gly
                 155                 160                 165

 Ile Leu Val Ala Gln Ile Phe Gly Leu Glu Phe Ile Leu Gly Ser
                 170                 175                 180

 Glu Glu Leu Trp Pro Leu Leu Leu Gly Phe Thr Ile Leu Pro Ala
                 185                 190                 195

 Ile Leu Gln Ser Ala Ala Leu Pro Phe Cys Pro Glu Ser Pro Arg
                 200                 205                 210

 Phe Leu Leu Ile Asn Arg Lys Glu Glu Glu Asn Ala Lys Gln Ile
                 215                 220                 225

 Leu Gln Arg Leu Trp Gly Thr Gln Asp Val Ser Gln Asp Ile Gln
                 230                 235                 240

 Glu Met Lys Asp Glu Ser Ala Arg Met Ser Gln Glu Lys Gln Val
                 245                 250                 255

 Thr Val Leu Glu Leu Phe Arg Val Ser Ser Tyr Arg Gln Pro Ile
                 260                 265                 270

 Ile Ile Ser Ile Val Leu Gln Leu Ser Gln Gln Leu Ser Gly Ile
                 275                 280                 285

 Asn Ala Val Phe Tyr Tyr Ser Thr Gly Ile Phe Lys Asp Ala Gly
                 290                 295                 300

 Val Gln Glu Pro Ile Tyr Ala Thr Ile Gly Ala Gly Val Val Asn
                 305                 310                 315

 Thr Ile Phe Thr Val Val Ser Leu Phe Leu Val Glu Arg Ala Gly
                 320                 325                 330

 Arg Arg Thr Leu His Met Ile Gly Leu Gly Gly Met Ala Phe Cys
                 335                 340                 345

 Ser Thr Leu Met Thr Val Ser Leu Leu Leu Lys Asp Asn Tyr Asn
                 350                 355                 360

 Gly Met Ser Phe Val Cys Ile Gly Ala Ile Leu Val Phe Val Ala
                 365                 370                 375

 Phe Phe Glu Ile Gly Pro Gly Pro Ile Pro Trp Phe Ile Val Ala
                 380                 385                 390

 Glu Leu Phe Ser Gln Gly Pro Arg Pro Ala Ala Met Ala Val Ala
                 395                 400                 405

 Gly Cys Ser Asn Trp Thr Ser Asn Phe Leu Val Gly Leu Leu Phe
                 410                 415                 420

 Pro Ser Ala Ala His Tyr Leu Gly Ala Tyr Val Phe Ile Ile Phe
                 425                 430                 435

 Thr Gly Phe Leu Ile Thr Phe Leu Ala Phe Thr Phe Phe Lys Val
                 440                 445                 450

 Pro Glu Thr Arg Gly Arg Thr Phe Glu Asp Ile Thr Arg Ala Phe
                 455                 460                 465

 Glu Gly Gln Ala His Gly Ala Asp Arg Ser Gly Lys Asp Gly Val
                 470                 475                 480

 Met Glu Met Asn Ser Ile Glu Pro Ala Lys Glu Thr Thr Thr Asn
                 485                 490                 495

 Val


<210> 619
<211> 2192
<212> DNA
<213> Homo sapien

<400> 619
 cggcgccggg gaccgctgcc accccgccta gcgcagcgcc ccgtccttcc 50

 gcagcccaac cgcctcttcc cgccccgccc catcccgccc acgggctcca 100

 gtgggcggga ccagaggagt cccgcgttcg gggagtatgt caaggccgtg 150

 acccgtgtat tattgtccga gtggccggaa cgggagccaa catggcagcg 200

 gggttcgggc gatgctgcag ggtcctgaga agtatttctc gttttcattg 250

 gagatcacag catacaaaag ccaatcgaca acgtgaacca ggattaggat 300

 ttagttttga gttcaccgaa cagcagaaag aatttcaagc tactgctcgt 350

 aaatttgcca gagaggaaat catcccagtg gctgcagaat atgataaaac 400

 tggtgaatat ccagtccccc taattagaag agcctgggaa cttggtttaa 450

 tgaacacaca cattccagag aactgtggag gtcttggact tggaactttt 500

 gatgcttgtt taattagtga agaattggct tatggatgta caggggttca 550

 gactgctatt gaaggaaatt ctttggggca aatgcctatt attattgctg 600

 gaaatgatca acaaaagaag aagtatttgg ggagaatgac tgaggagcca 650

 ttgatgtgtg cttattgtgt aacagaacct ggagcaggct ctgatgtagc 700

 tggtataaag accaaagcag aaaagaaagg agatgagtat attattaatg 750

 gtcagaagat gtggataacc aacggaggaa aagctaattg gtatttttta 800

 ttggcacgtt ctgatccaga tcctaaagct cctgctaata aagcctttac 850

 tggattcatt gtggaagcag ataccccagg aattcagatt gggagaaagg 900

 aattaaacat gggccagcga tgttcagata ctagaggaat tgtcttcgaa 950

 gatgtgaaag tgcctaaaga aaatgtttta attggtgacg gagctggttt 1000

 caaagttgca atgggagctt ttgataaaac cagacctgta gtagctgctg 1050

 gtgctgttgg attagcacaa agagctttgg atgaagctac caagtatgcc 1100

 ctggaaagga aaactttcgg aaagctactt gtagagcacc aagcaatatc 1150

 atttatgctg gctgaaatgg caatgaaagt tgaactagct agaatgagtt 1200

 accagagagc agcttgggag gttgattctg gtcgtcgaaa tacctattat 1250

 gcttctattg caaaggcatt tgctggagat attgcaaatc agttagctac 1300

 tgatgctgtg cagatacttg gaggcaatgg atttaataca gaatatcctg 1350

 tagaaaaact aatgagggat gccaaaatct atcagattta tgaaggtact 1400

 tcacaaattc aaagacttat tgtagcccgt gaacacattg acaagtacaa 1450

 aaattaaaaa aattactgta gaaatattga ataactagaa cacaagccac 1500

 tgtttcagct ccagaaaaaa gaaagggctt taacgttttt tccagtgaaa 1550

 acaaatcctc ttatattaaa tctaagcaac tgcttattat agtagtttat 1600

 acttttgctt aactctgtta tgtctcttaa gcaggtttgg tttttattaa 1650

 aatgatgtgt tttctttagt accactttac ttgaattaca ttaacctaga 1700

 aaactacata ggttattttg atctcttaag attaatgtag cagaaatttc 1750

 ttggaatttt atttttgtaa tgacagaaaa gtgggcttag aaagtattca 1800

 agatgttaca aaatttacat ttagaaaata ttgtagtatt tgaatactgt 1850

 caacttgaca gtaactttgt agacttaatg gtattattaa agttcttttt 1900

 attgcagttt ggaaagcatt tgtgaaactt tctgtttggc acagaaacag 1950

 tcaaaatttt gacattcata ttctcctatt ttacagctac aagaactttc 2000

 ttgaaaatct tatttaattc tgagcccata tttcacttac cttatttaaa 2050

 ataaatcaat aaagcttgcc ttaaattatt tttatatgac tgttggtctc 2100

 taggtagcct ttggtctatt gtacacaatc tcatttcata tgtttgcatt 2150

 ttggcaaaga acttaataaa attgttcagt gcttattatc at 2192

<210> 620
<211> 421
<212> PRT
<213> Homo sapien

<400> 620
 Met Ala Ala Gly Phe Gly Arg Cys Cys Arg Val Leu Arg Ser Ile
   1               5                  10                  15

 Ser Arg Phe His Trp Arg Ser Gln His Thr Lys Ala Asn Arg Gln
                  20                  25                  30

 Arg Glu Pro Gly Leu Gly Phe Ser Phe Glu Phe Thr Glu Gln Gln
                  35                  40                  45

 Lys Glu Phe Gln Ala Thr Ala Arg Lys Phe Ala Arg Glu Glu Ile
                  50                  55                  60

 Ile Pro Val Ala Ala Glu Tyr Asp Lys Thr Gly Glu Tyr Pro Val
                  65                  70                  75

 Pro Leu Ile Arg Arg Ala Trp Glu Leu Gly Leu Met Asn Thr His
                  80                  85                  90

 Ile Pro Glu Asn Cys Gly Gly Leu Gly Leu Gly Thr Phe Asp Ala
                  95                 100                 105

 Cys Leu Ile Ser Glu Glu Leu Ala Tyr Gly Cys Thr Gly Val Gln
                 110                 115                 120

 Thr Ala Ile Glu Gly Asn Ser Leu Gly Gln Met Pro Ile Ile Ile
                 125                 130                 135

 Ala Gly Asn Asp Gln Gln Lys Lys Lys Tyr Leu Gly Arg Met Thr
                 140                 145                 150

 Glu Glu Pro Leu Met Cys Ala Tyr Cys Val Thr Glu Pro Gly Ala
                 155                 160                 165

 Gly Ser Asp Val Ala Gly Ile Lys Thr Lys Ala Glu Lys Lys Gly
                 170                 175                 180

 Asp Glu Tyr Ile Ile Asn Gly Gln Lys Met Trp Ile Thr Asn Gly
                 185                 190                 195

 Gly Lys Ala Asn Trp Tyr Phe Leu Leu Ala Arg Ser Asp Pro Asp
                 200                 205                 210

 Pro Lys Ala Pro Ala Asn Lys Ala Phe Thr Gly Phe Ile Val Glu
                 215                 220                 225

 Ala Asp Thr Pro Gly Ile Gln Ile Gly Arg Lys Glu Leu Asn Met
                 230                 235                 240

 Gly Gln Arg Cys Ser Asp Thr Arg Gly Ile Val Phe Glu Asp Val
                 245                 250                 255

 Lys Val Pro Lys Glu Asn Val Leu Ile Gly Asp Gly Ala Gly Phe
                 260                 265                 270

 Lys Val Ala Met Gly Ala Phe Asp Lys Thr Arg Pro Val Val Ala
                 275                 280                 285

 Ala Gly Ala Val Gly Leu Ala Gln Arg Ala Leu Asp Glu Ala Thr
                 290                 295                 300

 Lys Tyr Ala Leu Glu Arg Lys Thr Phe Gly Lys Leu Leu Val Glu
                 305                 310                 315

 His Gln Ala Ile Ser Phe Met Leu Ala Glu Met Ala Met Lys Val
                 320                 325                 330

 Glu Leu Ala Arg Met Ser Tyr Gln Arg Ala Ala Trp Glu Val Asp
                 335                 340                 345

 Ser Gly Arg Arg Asn Thr Tyr Tyr Ala Ser Ile Ala Lys Ala Phe
                 350                 355                 360

 Ala Gly Asp Ile Ala Asn Gln Leu Ala Thr Asp Ala Val Gln Ile
                 365                 370                 375

 Leu Gly Gly Asn Gly Phe Asn Thr Glu Tyr Pro Val Glu Lys Leu
                 380                 385                 390

 Met Arg Asp Ala Lys Ile Tyr Gln Ile Tyr Glu Gly Thr Ser Gln
                 395                 400                 405

 Ile Gln Arg Leu Ile Val Ala Arg Glu His Ile Asp Lys Tyr Lys
                 410                 415                 420

 Asn


<210> 621
<211> 836
<212> DNA
<213> Homo sapien

<400> 621
 gtgaaacacc ctcggctggg aagtcagttc gttctctcct ctcctctctt 50

 cttgtttgaa catggtgcgg actaaagcag acagtgttcc aggcacttac 100

 agaaaagtgg tggctgctcg agcccccaga aaggtgcttg gttcttccac 150

 ctctgccact aattcgacat cagtttcatc gaggaaagct gaaaataaat 200

 atgcaggagg gaaccccgtt tgcgtgcgcc caactcccaa gtggcaaaaa 250

 ggaattggag aattctttag gttgtcccct aaagattctg aaaaagagaa 300

 tcagattcct gaagaggcag gaagcagtgg cttaggaaaa gcaaagagaa 350

 aagcatgtcc tttgcaacct gatcacacaa atgatgaaaa agaatagaac 400

 tttctcattc atctttgaat aacgtctcct tgtttaccct ggtattctag 450

 aatgtaaatt tacataaatg tgtttgttcc aattagcttt gttgaacagg 500

 catttaatta aaaaatttag gtttaaattt agatgttcaa aagtagttgt 550

 gaaatttgag aatttgtaag actaattatg gtaacttagc ttagtattca 600

 atataatgca ttgtttggtt tcttttacca aattaagtgt ctagttcttg 650

 ctaaaatcaa gtcattgcat tgtgttctaa ttacaagtat gttgtatttg 700

 agatttgctt agattgttgt actgctgcca tttttattgg tgtttgatta 750

 ttggaatggt gccatattgt cactccttct acttgcttta aaaagcagag 800

 ttagattttt gcacattaaa aaattcagta ttaatt 836

<210> 622
<211> 111
<212> PRT
<213> Homo sapien

<400> 622
 Met Val Arg Thr Lys Ala Asp Ser Val Pro Gly Thr Tyr Arg Lys
   1               5                  10                  15

 Val Val Ala Ala Arg Ala Pro Arg Lys Val Leu Gly Ser Ser Thr
                  20                  25                  30

 Ser Ala Thr Asn Ser Thr Ser Val Ser Ser Arg Lys Ala Glu Asn
                  35                  40                  45

 Lys Tyr Ala Gly Gly Asn Pro Val Cys Val Arg Pro Thr Pro Lys
                  50                  55                  60

 Trp Gln Lys Gly Ile Gly Glu Phe Phe Arg Leu Ser Pro Lys Asp
                  65                  70                  75

 Ser Glu Lys Glu Asn Gln Ile Pro Glu Glu Ala Gly Ser Ser Gly
                  80                  85                  90

 Leu Gly Lys Ala Lys Arg Lys Ala Cys Pro Leu Gln Pro Asp His
                  95                 100                 105

 Thr Asn Asp Glu Lys Glu
                 110

<210> 623
<211> 5316
<212> DNA
<213> Homo sapien

<400> 623
 cggacgcgtg ggaacgaagc cacccattac ggtatgatga tgtcaaacgt 50

 gatgctgatg ctacagttac agcccctgct ggcgcagcct ctctgattct 100

 ctctccctct ccgcgtccag tgctgggctt tttcagacaa gtgcatctcc 150

 taaccaggtc acatttcagc cgcgacccac tctccgccag tcaccggagg 200

 cagaccgcgg gaggagagct gaggacagcc gcgtgcgctt cgccagcagc 250

 ggggtgggag gaaggacatt aaaatactgc agaagtcaag accccccagg 300

 tcgaacccag accacgatgc gcgccccggg ctgcgggcgg ctggtgctgc 350

 cgctgctgct cctggccgcg gcagccctgg ccgaaggcga cgccaagggg 400

 ctcaaggagg gcgagacccc cggcaatttc atggaggacg agcaatggct 450

 gtcgtccatc tcgcagtaca gcggcaagat caagcactgg aaccgcttcc 500

 gagacgaagt ggaggatgac tatatcaaga gctgggagga caatcagcaa 550

 ggagatgaag ccctggatac caccaaggac ccctgccaga aggtgaagtg 600

 cagccgccac aaggtgtgca ttgcccaggg ctaccagcgg gccatgtgca 650

 tcagtcgcaa gaagctggag cacaggatca agcagccgac cgtgaaactc 700

 catggaaaca aagactccat ctgcaagccc tgccacatgg cccagcttgc 750

 ctctgtctgc ggctcagatg gccacactta cagctctgtg tgtaagctgg 800

 agcaacaggc gtgcctgagc agcaagcagc tggcggtgcg atgcgagggc 850

 ccctgcccct gccccacgga gcaggctgcc acctccaccg ccgatggcaa 900

 accagagact tgcaccggtc aggacctggc tgacctggga gatcggctgc 950

 gggactggtt ccagctcctt catgagaact ccaagcagaa tggctcagcc 1000

 agcagtgtag ccggcccggc cagcgggctg gacaagagcc tgggggccag 1050

 ctgcaaggac tccattggct ggatgttctc caagctggac accagtgctg 1100

 acctcttcct ggaccagacg gagctggccg ccatcaacct ggacaagtac 1150

 gaggtctgca tccgtccctt cttcaactcc tgtgacacct acaaggatgg 1200

 ccgggtctct actgctgagt ggtgcttctg cttctggagg gagaagcccc 1250

 cctgcctggc agagctggag cgcatccaga tccaggaggc cgccaagaag 1300

 aagccaggca tcttcatccc gagctgcgac gaggatggct actaccggaa 1350

 gatgcagtgt gaccagagca gcggtgactg ctggtgtgtg gaccagctgg 1400

 gcctggagct gactggcacg cgcacgcatg ggagccccga ctgcgatgac 1450

 atcgtgggct tctcggggga ctttggaagc ggtgtcggct gggaggatga 1500

 ggaggagaag gagacggagg aagcaggcga ggaggccgag gaggaggagg 1550

 gcgaggcagg cgaggctgac gacgggggct acatctggta gacgccctca 1600

 gaagccggct gccggggggg actcaacagc agagctctga gcagcagcag 1650

 gcaacttcga gaacggatcc agaaatgcag tcagaaggac cctgctccac 1700

 ctggggggac tgggagtgtg agtgtgcatg gcatgtgtgt ggcacagatg 1750

 gctgggacgg gtgacagtgt gagtgcatgt gtgcatgcat gtgtgtatgt 1800

 gtgtgtgtgt gtggcatgcg ctgacaaatg tgtccttgat ccacactgct 1850

 cctggcagag tgagtaaccc aaaggcccct tcggcctcct tgtagctgtt 1900

 ttctttcctt ttgttgttgg ttttaaaata cattcacaca caaatacaaa 1950

 ttgacaggtc aaaatccatg aaatgagatc ccccagccgt gtcctccagc 2000

 ccagccctga ccccttggtt tctaccctgg ctccccttgg tttctaccct 2050

 ggctcaaccg acccctgtct gcccttctcc ctcctgcttc tgaggtcaag 2100

 ctctggcctg cgagcctgtc cccattgcaa aggggaggga ggggcaggga 2150

 gctgtctacc agctgaggtc ctcccaaaac tgggccgatg tggtgtgaca 2200

 tccccaccag cctcagatga gacgggccag gacgcccagc cacagcaagc 2250

 cctgtccctt tgccggatcc ccaaacacta gagaagctct cctaacccaa 2300

 ggcggagaat gaaggtggtg gcggcagagg aggagggcag cagctgagag 2350

 gccagggaca gggtgcctcg ccaagctgtc tgaggtctgt cccaggtggc 2400

 ccaggtggtg caggtagaac agggtgagga gagggggtcg gctcaacagg 2450

 aggaggctgt ggctgcagag cctggaggag cttttaggtg ttgagatggg 2500

 gcagctctga atcctagacc ctggaatagc ctgtcccttt tctctgggtc 2550

 tcgtggtgga gccatgatct gggctgctct cttggggaca ctgggtggtg 2600

 gttacacagt tgacctctgc ctggctcccc cttggtgcaa ctcctgcctc 2650

 catccccctt gctggggtcc cctcatccac ttgagggcgc ctgagggcca 2700

 ggagcagcag gcaaggagcc tgggtctagg ctaagggggt gtgtgcccac 2750

 ctcctccctg acccttaaca ctcctgtcct gcccagacca acagagagag 2800

 ctgtccctga gaccccggag agaagcagct gccgaaagct gcagcctttc 2850

 cgcactctga gaccatgatc ttcctcctgc caggggagag ccacccacag 2900

 gccatgtcca gccccacttc cctcagcccc cagggcttcc ttctggcccc 2950

 tctgaggatt ccctagggct gccccgcaga ggggcttccc caagctctgt 3000

 tttgaagcct gcaatgtgga aaagtgagaa gtcagaggga acaggacagg 3050

 tgcagccggg ctctgaggcc acacctcaca cctcgctgtt ccccaacatc 3100

 ccctgagcag tgtgagctca tctcaccaga tgagaagagg ccctgtgcat 3150

 ttcttttgtt tgtttgttgc tgttttcccc cacccatcca gttctcctca 3200

 gcaaagcaaa ttccttaaca cctttggtgg agaatttctt acccagactt 3250

 ggggctgtga tgcccttcag tgcgtggtga gtgcagcgtg tgtgcgtgtg 3300

 cctgtgtgtg aacctggggg ccatcctggt ggcctgggag cgtgaggaga 3350

 ggccccctgt gtgctgggtg agtggtgggt gtggggtcaa tgcagtgagg 3400

 ctctctgggt gaggctccca acctggcagt ccccagcctc ccagcatctg 3450

 tgagcgtctg ttggacttta cagaagagcc tcatcccgtc tgcccctcac 3500

 tctgccctgg aatcaacatc ttccgagtcc ttcttggggg aaatagcaga 3550

 gccccactta actccataaa ctgcttccca ttccgcagcc cagttctgat 3600

 tgttgaggtg tcgcgtcgtt ccaggtcccc cagtcccctc tttctcctgt 3650

 cctctctctg tccttcacct ccccactcca gccccggctc agttcaggga 3700

 aatgctgttc catatcagcc ctctgctctc tgaggcagcc gcgcctctga 3750

 ctcggagcta cttgaaactt ctgctcttgc taggattgga gtctacctat 3800

 ctcttccatt tgtcccagct ggagttctgg aactttcctc ctcggggtgg 3850

 gggtgggggt tgttaaggat gctggggggc ctggggaagg aaggagttca 3900

 gaggaagggt gtcccctgtc ctcttgatgt caccctccgc tcctgggaca 3950

 cgtgctctct ctgtctctgg gtcttctggc tgtgcacgtt tgtgtgtcct 4000

 tgtaaatatg ttttaggaag aaagcaaaag ggactgaact agcctctggt 4050

 aggattgcag gggtccagcc ttgcctgttt ccgaagcccc cacactgcct 4100

 ttcgccccac tgagactggt cccctcaaaa ggtagacaaa acagcagctc 4150

 cctgtggagc tgaagggcgg cctcaaagtg gctttttgtt agacaaggtt 4200

 aaggtttcct catgagcaag gttgcagatc ggtccttcct cagctccttg 4250

 atttgtgacc ttgaccaagg ggcctgccac ccagcccctc cagtgccctc 4300

 tcctcgatgc ctcgctcctt cctgccccca ctcccctggc ttaggcaggt 4350

 aggggaatta gggccatgct ggaagaagct taaccatgtg ttcaaagaac 4400

 ggtttcttgc ttgcttggtc ctggaactcc ccttggctgc cccaggcctc 4450

 cttggcccat gggtgctggg ggaggtggat gtcagatctg gtaggttgca 4500

 gcagagaaaa taaatgtgcc ttgagagacc actcagagag ggtccaaggg 4550

 tgatggagaa ggaagcatgg cctgggagct tggaagggag gggtggtggg 4600

 tggcggcatc ttgactgccc cctgttgtcc cacacgtggg gggtggtcac 4650

 cccccttcac tccagcccgc ctgccttcag ccttccatga gcttcacctg 4700

 cttccaactt cactttggag ggggtggggt ccgttggcat caacacgggg 4750

 accctctgct tcaccaaagc ccgagccctc agcccctggg gagaacaaat 4800

 ggctgagctt tgatacctgg ggtcgtcgag aggctgcggg ctggcggcag 4850

 tcccagggga gagacaccac agaaggagac ccagacatcc cgaggaagtt 4900

 cccagcagag caaactgctt tccagcctga agcctgctta aactgtgtga 4950

 tgtgcaataa ctgagcttag agttaggaat tgtgttcaag tgcttggatt 5000

 tccgtctgta gatttaactg ctgaaattgt atctctcagt aattttagat 5050

 gtcttttaaa aaattgaaaa acaaagtgtt agactgtgtg cgtgtgcgtt 5100

 gatgggcact caagagtccc gtgagtcatc cagccctgcc tttcccctgc 5150

 gcccccatcc tctcacgtcc cgccctgcct ccacttgggg accctgcctc 5200

 gtgtcgtctt tatctgccta ttactcagcc taaggaaaca agtacactcc 5250

 acacatgcat aaaggaaatc aaatgttatt tttaagaaaa tggaaaataa 5300

 aaactttata aacacc 5316

<210> 624
<211> 424
<212> PRT
<213> Homo sapien

<400> 624
 Met Arg Ala Pro Gly Cys Gly Arg Leu Val Leu Pro Leu Leu Leu
   1               5                  10                  15

 Leu Ala Ala Ala Ala Leu Ala Glu Gly Asp Ala Lys Gly Leu Lys
                  20                  25                  30

 Glu Gly Glu Thr Pro Gly Asn Phe Met Glu Asp Glu Gln Trp Leu
                  35                  40                  45

 Ser Ser Ile Ser Gln Tyr Ser Gly Lys Ile Lys His Trp Asn Arg
                  50                  55                  60

 Phe Arg Asp Glu Val Glu Asp Asp Tyr Ile Lys Ser Trp Glu Asp
                  65                  70                  75

 Asn Gln Gln Gly Asp Glu Ala Leu Asp Thr Thr Lys Asp Pro Cys
                  80                  85                  90

 Gln Lys Val Lys Cys Ser Arg His Lys Val Cys Ile Ala Gln Gly
                  95                 100                 105

 Tyr Gln Arg Ala Met Cys Ile Ser Arg Lys Lys Leu Glu His Arg
                 110                 115                 120

 Ile Lys Gln Pro Thr Val Lys Leu His Gly Asn Lys Asp Ser Ile
                 125                 130                 135

 Cys Lys Pro Cys His Met Ala Gln Leu Ala Ser Val Cys Gly Ser
                 140                 145                 150

 Asp Gly His Thr Tyr Ser Ser Val Cys Lys Leu Glu Gln Gln Ala
                 155                 160                 165

 Cys Leu Ser Ser Lys Gln Leu Ala Val Arg Cys Glu Gly Pro Cys
                 170                 175                 180

 Pro Cys Pro Thr Glu Gln Ala Ala Thr Ser Thr Ala Asp Gly Lys
                 185                 190                 195

 Pro Glu Thr Cys Thr Gly Gln Asp Leu Ala Asp Leu Gly Asp Arg
                 200                 205                 210

 Leu Arg Asp Trp Phe Gln Leu Leu His Glu Asn Ser Lys Gln Asn
                 215                 220                 225

 Gly Ser Ala Ser Ser Val Ala Gly Pro Ala Ser Gly Leu Asp Lys
                 230                 235                 240

 Ser Leu Gly Ala Ser Cys Lys Asp Ser Ile Gly Trp Met Phe Ser
                 245                 250                 255

 Lys Leu Asp Thr Ser Ala Asp Leu Phe Leu Asp Gln Thr Glu Leu
                 260                 265                 270

 Ala Ala Ile Asn Leu Asp Lys Tyr Glu Val Cys Ile Arg Pro Phe
                 275                 280                 285

 Phe Asn Ser Cys Asp Thr Tyr Lys Asp Gly Arg Val Ser Thr Ala
                 290                 295                 300

 Glu Trp Cys Phe Cys Phe Trp Arg Glu Lys Pro Pro Cys Leu Ala
                 305                 310                 315

 Glu Leu Glu Arg Ile Gln Ile Gln Glu Ala Ala Lys Lys Lys Pro
                 320                 325                 330

 Gly Ile Phe Ile Pro Ser Cys Asp Glu Asp Gly Tyr Tyr Arg Lys
                 335                 340                 345

 Met Gln Cys Asp Gln Ser Ser Gly Asp Cys Trp Cys Val Asp Gln
                 350                 355                 360

 Leu Gly Leu Glu Leu Thr Gly Thr Arg Thr His Gly Ser Pro Asp
                 365                 370                 375

 Cys Asp Asp Ile Val Gly Phe Ser Gly Asp Phe Gly Ser Gly Val
                 380                 385                 390

 Gly Trp Glu Asp Glu Glu Glu Lys Glu Thr Glu Glu Ala Gly Glu
                 395                 400                 405

 Glu Ala Glu Glu Glu Glu Gly Glu Ala Gly Glu Ala Asp Asp Gly
                 410                 415                 420

 Gly Tyr Ile Trp


<210> 625
<211> 5316
<212> DNA
<213> Homo sapien

<400> 625
 cggacgcgtg ggaacgaagc cacccattac ggtatgatga tgtcaaacgt 50

 gatgctgatg ctacagttac agcccctgct ggcgcagcct ctctgattct 100

 ctctccctct ccgcgtccag tgctgggctt tttcagacaa gtgcatctcc 150

 taaccaggtc acatttcagc cgcgacccac tctccgccag tcaccggagg 200

 cagaccgcgg gaggagagct gaggacagcc gcgtgcgctt cgccagcagc 250

 ggggtgggag gaaggacatt aaaatactgc agaagtcaag accccccagg 300

 tcgaacccag accacgatgc gcgccccggg ctgcgggcgg ctggtgctgc 350

 cgctgctgct cctggccgcg gcagccctgg ccgaaggcga cgccaagggg 400

 ctcaaggagg gcgagacccc cggcaatttc atggaggacg agcaatggct 450

 gtcgtccatc tcgcagtaca gcggcaagat caagcactgg aaccgcttcc 500

 gagacgaagt ggaggatgac tatatcaaga gctgggagga caatcagcaa 550

 ggagatgaag ccctggatac caccaaggac ccctgccaga aggtgaagtg 600

 cagccgccac aaggtgtgca ttgcccaggg ctaccagcgg gccatgtgca 650

 tcagtcgcaa gaagctggag cacaggatca agcagccgac cgtgaaactc 700

 catggaaaca aagactccat ctgcaagccc tgccacatgg cccagcttgc 750

 ctctgtctgc ggctcagatg gccacactta cagctctgtg tgtaagctgg 800

 agcaacaggc gtgcctgagc agcaagcagc tggcggtgcg atgcgagggc 850

 ccctgcccct gccccacgga gcaggctgcc acctccaccg ccgatggcaa 900

 accagagact tgcaccggtc aggacctggc tgacctggga gatcggctgc 950

 gggactggtt ccagctcctt catgagaact ccaagcagaa tggctcagcc 1000

 agcagtgtag ccggcccggc cagcgggctg gacaagagcc tgggggccag 1050

 ctgcaaggac tccattggct ggatgttctc caagctggac accagtgctg 1100

 acctcttcct ggaccagacg gagctggccg ccatcaacct ggacaagtac 1150

 gaggtctgca tccgtccctt cttcaactcc tgtgacacct acaaggatgg 1200

 ccgggtctct actgctgagt ggtgcttctg cttctggagg gagaagcccc 1250

 cctgcctggc agagctggag cgcatccaga tccaggaggc cgccaagaag 1300

 aagccaggca tcttcatccc gagctgcgac gaggatggct actaccggaa 1350

 gatgcagtgt gaccagagca gcggtgactg ctggtgtgtg gaccagctgg 1400

 gcctggagct gactggcacg cgcacgcatg ggagccccga ctgcgatgac 1450

 atcgtgggct tctcggggga ctttggaagc ggtgtcggct gggaggatga 1500

 ggaggagaag gagacggagg aagcaggcga ggaggccgag gaggaggagg 1550

 gcgaggcagg cgaggctgac gacgggggct acatctggta gacgccctca 1600

 gaagccggct gccggggggg actcaacagc agagctctga gcagcagcag 1650

 gcaacttcga gaacggatcc agaaatgcag tcagaaggac cctgctccac 1700

 ctggggggac tgggagtgtg agtgtgcatg gcatgtgtgt ggcacagatg 1750

 gctgggacgg gtgacagtgt gagtgcatgt gtgcatgcat gtgtgtatgt 1800

 gtgtgtgtgt gtggcatgcg ctgacaaatg tgtccttgat ccacactgct 1850

 cctggcagag tgagtaaccc aaaggcccct tcggcctcct tgtagctgtt 1900

 ttctttcctt ttgttgttgg ttttaaaata cattcacaca caaatacaaa 1950

 ttgacaggtc aaaatccatg aaatgagatc ccccagccgt gtcctccagc 2000

 ccagccctga ccccttggtt tctaccctgg ctccccttgg tttctaccct 2050

 ggctcaaccg acccctgtct gcccttctcc ctcctgcttc tgaggtcaag 2100

 ctctggcctg cgagcctgtc cccattgcaa aggggaggga ggggcaggga 2150

 gctgtctacc agctgaggtc ctcccaaaac tgggccgatg tggtgtgaca 2200

 tccccaccag cctcagatga gacgggccag gacgcccagc cacagcaagc 2250

 cctgtccctt tgccggatcc ccaaacacta gagaagctct cctaacccaa 2300

 ggcggagaat gaaggtggtg gcggcagagg aggagggcag cagctgagag 2350

 gccagggaca gggtgcctcg ccaagctgtc tgaggtctgt cccaggtggc 2400

 ccaggtggtg caggtagaac agggtgagga gagggggtcg gctcaacagg 2450

 aggaggctgt ggctgcagag cctggaggag cttttaggtg ttgagatggg 2500

 gcagctctga atcctagacc ctggaatagc ctgtcccttt tctctgggtc 2550

 tcgtggtgga gccatgatct gggctgctct cttggggaca ctgggtggtg 2600

 gttacacagt tgacctctgc ctggctcccc cttggtgcaa ctcctgcctc 2650

 catccccctt gctggggtcc cctcatccac ttgagggcgc ctgagggcca 2700

 ggagcagcag gcaaggagcc tgggtctagg ctaagggggt gtgtgcccac 2750

 ctcctccctg acccttaaca ctcctgtcct gcccagacca acagagagag 2800

 ctgtccctga gaccccggag agaagcagct gccgaaagct gcagcctttc 2850

 cgcactctga gaccatgatc ttcctcctgc caggggagag ccacccacag 2900

 gccatgtcca gccccacttc cctcagcccc cagggcttcc ttctggcccc 2950

 tctgaggatt ccctagggct gccccgcaga ggggcttccc caagctctgt 3000

 tttgaagcct gcaatgtgga aaagtgagaa gtcagaggga acaggacagg 3050

 tgcagccggg ctctgaggcc acacctcaca cctcgctgtt ccccaacatc 3100

 ccctgagcag tgtgagctca tctcaccaga tgagaagagg ccctgtgcat 3150

 ttcttttgtt tgtttgttgc tgttttcccc cacccatcca gttctcctca 3200

 gcaaagcaaa ttccttaaca cctttggtgg agaatttctt acccagactt 3250

 ggggctgtga tgcccttcag tgcgtggtga gtgcagcgtg tgtgcgtgtg 3300

 cctgtgtgtg aacctggggg ccatcctggt ggcctgggag cgtgaggaga 3350

 ggccccctgt gtgctgggtg agtggtgggt gtggggtcaa tgcagtgagg 3400

 ctctctgggt gaggctccca acctggcagt ccccagcctc ccagcatctg 3450

 tgagcgtctg ttggacttta cagaagagcc tcatcccgtc tgcccctcac 3500

 tctgccctgg aatcaacatc ttccgagtcc ttcttggggg aaatagcaga 3550

 gccccactta actccataaa ctgcttccca ttccgcagcc cagttctgat 3600

 tgttgaggtg tcgcgtcgtt ccaggtcccc cagtcccctc tttctcctgt 3650

 cctctctctg tccttcacct ccccactcca gccccggctc agttcaggga 3700

 aatgctgttc catatcagcc ctctgctctc tgaggcagcc gcgcctctga 3750

 ctcggagcta cttgaaactt ctgctcttgc taggattgga gtctacctat 3800

 ctcttccatt tgtcccagct ggagttctgg aactttcctc ctcggggtgg 3850

 gggtgggggt tgttaaggat gctggggggc ctggggaagg aaggagttca 3900

 gaggaagggt gtcccctgtc ctcttgatgt caccctccgc tcctgggaca 3950

 cgtgctctct ctgtctctgg gtcttctggc tgtgcacgtt tgtgtgtcct 4000

 tgtaaatatg ttttaggaag aaagcaaaag ggactgaact agcctctggt 4050

 aggattgcag gggtccagcc ttgcctgttt ccgaagcccc cacactgcct 4100

 ttcgccccac tgagactggt cccctcaaaa ggtagacaaa acagcagctc 4150

 cctgtggagc tgaagggcgg cctcaaagtg gctttttgtt agacaaggtt 4200

 aaggtttcct catgagcaag gttgcagatc ggtccttcct cagctccttg 4250

 atttgtgacc ttgaccaagg ggcctgccac ccagcccctc cagtgccctc 4300

 tcctcgatgc ctcgctcctt cctgccccca ctcccctggc ttaggcaggt 4350

 aggggaatta gggccatgct ggaagaagct taaccatgtg ttcaaagaac 4400

 ggtttcttgc ttgcttggtc ctggaactcc ccttggctgc cccaggcctc 4450

 cttggcccat gggtgctggg ggaggtggat gtcagatctg gtaggttgca 4500

 gcagagaaaa taaatgtgcc ttgagagacc actcagagag ggtccaaggg 4550

 tgatggagaa ggaagcatgg cctgggagct tggaagggag gggtggtggg 4600

 tggcggcatc ttgactgccc cctgttgtcc cacacgtggg gggtggtcac 4650

 cccccttcac tccagcccgc ctgccttcag ccttccatga gcttcacctg 4700

 cttccaactt cactttggag ggggtggggt ccgttggcat caacacgggg 4750

 accctctgct tcaccaaagc ccgagccctc agcccctggg gagaacaaat 4800

 ggctgagctt tgatacctgg ggtcgtcgag aggctgcggg ctggcggcag 4850

 tcccagggga gagacaccac agaaggagac ccagacatcc cgaggaagtt 4900

 cccagcagag caaactgctt tccagcctga agcctgctta aactgtgtga 4950

 tgtgcaataa ctgagcttag agttaggaat tgtgttcaag tgcttggatt 5000

 tccgtctgta gatttaactg ctgaaattgt atctctcagt aattttagat 5050

 gtcttttaaa aaattgaaaa acaaagtgtt agactgtgtg cgtgtgcgtt 5100

 gatgggcact caagagtccc gtgagtcatc cagccctgcc tttcccctgc 5150

 gcccccatcc tctcacgtcc cgccctgcct ccacttgggg accctgcctc 5200

 gtgtcgtctt tatctgccta ttactcagcc taaggaaaca agtacactcc 5250

 acacatgcat aaaggaaatc aaatgttatt tttaagaaaa tggaaaataa 5300

 aaactttata aacacc 5316

<210> 626
<211> 424
<212> PRT
<213> Homo sapien

<400> 626
 Met Arg Ala Pro Gly Cys Gly Arg Leu Val Leu Pro Leu Leu Leu
   1               5                  10                  15

 Leu Ala Ala Ala Ala Leu Ala Glu Gly Asp Ala Lys Gly Leu Lys
                  20                  25                  30

 Glu Gly Glu Thr Pro Gly Asn Phe Met Glu Asp Glu Gln Trp Leu
                  35                  40                  45

 Ser Ser Ile Ser Gln Tyr Ser Gly Lys Ile Lys His Trp Asn Arg
                  50                  55                  60

 Phe Arg Asp Glu Val Glu Asp Asp Tyr Ile Lys Ser Trp Glu Asp
                  65                  70                  75

 Asn Gln Gln Gly Asp Glu Ala Leu Asp Thr Thr Lys Asp Pro Cys
                  80                  85                  90

 Gln Lys Val Lys Cys Ser Arg His Lys Val Cys Ile Ala Gln Gly
                  95                 100                 105

 Tyr Gln Arg Ala Met Cys Ile Ser Arg Lys Lys Leu Glu His Arg
                 110                 115                 120

 Ile Lys Gln Pro Thr Val Lys Leu His Gly Asn Lys Asp Ser Ile
                 125                 130                 135

 Cys Lys Pro Cys His Met Ala Gln Leu Ala Ser Val Cys Gly Ser
                 140                 145                 150

 Asp Gly His Thr Tyr Ser Ser Val Cys Lys Leu Glu Gln Gln Ala
                 155                 160                 165

 Cys Leu Ser Ser Lys Gln Leu Ala Val Arg Cys Glu Gly Pro Cys
                 170                 175                 180

 Pro Cys Pro Thr Glu Gln Ala Ala Thr Ser Thr Ala Asp Gly Lys
                 185                 190                 195

 Pro Glu Thr Cys Thr Gly Gln Asp Leu Ala Asp Leu Gly Asp Arg
                 200                 205                 210

 Leu Arg Asp Trp Phe Gln Leu Leu His Glu Asn Ser Lys Gln Asn
                 215                 220                 225

 Gly Ser Ala Ser Ser Val Ala Gly Pro Ala Ser Gly Leu Asp Lys
                 230                 235                 240

 Ser Leu Gly Ala Ser Cys Lys Asp Ser Ile Gly Trp Met Phe Ser
                 245                 250                 255

 Lys Leu Asp Thr Ser Ala Asp Leu Phe Leu Asp Gln Thr Glu Leu
                 260                 265                 270

 Ala Ala Ile Asn Leu Asp Lys Tyr Glu Val Cys Ile Arg Pro Phe
                 275                 280                 285

 Phe Asn Ser Cys Asp Thr Tyr Lys Asp Gly Arg Val Ser Thr Ala
                 290                 295                 300

 Glu Trp Cys Phe Cys Phe Trp Arg Glu Lys Pro Pro Cys Leu Ala
                 305                 310                 315

 Glu Leu Glu Arg Ile Gln Ile Gln Glu Ala Ala Lys Lys Lys Pro
                 320                 325                 330

 Gly Ile Phe Ile Pro Ser Cys Asp Glu Asp Gly Tyr Tyr Arg Lys
                 335                 340                 345

 Met Gln Cys Asp Gln Ser Ser Gly Asp Cys Trp Cys Val Asp Gln
                 350                 355                 360

 Leu Gly Leu Glu Leu Thr Gly Thr Arg Thr His Gly Ser Pro Asp
                 365                 370                 375

 Cys Asp Asp Ile Val Gly Phe Ser Gly Asp Phe Gly Ser Gly Val
                 380                 385                 390

 Gly Trp Glu Asp Glu Glu Glu Lys Glu Thr Glu Glu Ala Gly Glu
                 395                 400                 405

 Glu Ala Glu Glu Glu Glu Gly Glu Ala Gly Glu Ala Asp Asp Gly
                 410                 415                 420

 Gly Tyr Ile Trp


<210> 627
<211> 3900
<212> DNA
<213> Homo sapien

<400> 627
 cgatggccct gcccagtccc agacagaacc tactacgtgc ggcggcagct 50

 ggggcgggaa ggcgggcgct gggggcgctg cggccgctgc agcgcagggt 100

 ccacctggtc ggctgcacct gtggaggagg aggtggattt caggcttccc 150

 gtagactgga agaatcggct caaaaccgct tgcctcgcag gggctgagct 200

 ggaggcagcg aggccgcccg acgcaggctt ccggcgagac atggcagggc 250

 aaggatggca gcccggcggc agggcccggc gaggagcgcg aacccgcggc 300

 cgcagttccc aggcgtctgc gggcgcgagc acgccgcgac cctgcgtgcg 350

 ccggggcggg ggggcggggc ctcgcctgca caaataggga cgagggggcg 400

 gggcggccac aatttcgcgc caaacttgac cgcgcgttct gctgtaacga 450

 gcgggctcgg aggtcctccc gctgctgtca tggttggttc gctaaactgc 500

 atcgtcgctg tgtcccagaa catgggcatc ggcaagaacg gggacctgcc 550

 ctggccaccg ctcaggaatg aattcagata tttccagaga atgaccacaa 600

 cctcttcagt agaaggtaaa cagaatctgg tgattatggg taagaagacc 650

 tggttctcca ttcctgagaa gaatcgacct ttaaagggta gaattaattt 700

 agttctcagc agagaactca aggaacctcc acaaggagct cattttcttt 750

 ccagaagtct agatgatgcc ttaaaactta ctgaacaacc agaattagca 800

 aataaagtag acatggtctg gatagttggt ggcagttctg tttataagga 850

 agccatgaat cacccaggcc atcttaaact atttgtgaca aggatcatgc 900

 aagactttga aagtgacacg ttttttccag aaattgattt ggagaaatat 950

 aaacttctgc cagaataccc aggtgttctc tctgatgtcc aggaggagaa 1000

 aggcattaag tacaaatttg aagtatatga gaagaatgat taatatgaag 1050

 gtgttttcta gtttaagttg ttccccctcc ctctgaaaaa agtatgtatt 1100

 tttacattag aaaaggtttt ttgttgactt tagatctata attatttcta 1150

 agcaacttgt ttttattccc cactactctt ctctctatca gataccattt 1200

 atgagacatt cttgctataa ctaagtgctt ctccaagacc ccaactgagt 1250

 ccccagcacc tgctacagtg agctgccatt ccacacccat cacatgtggc 1300

 actcttgcca gtccttgaca ttgtcgggct tttcacatgt tggtaatatt 1350

 tattaaagat gaagatccac atacccttca actgagcagt ttcactagtg 1400

 gaaataccaa aagcttccta cgtgtatatc cagaggtttg tagataaatg 1450

 ttgccacctt gtttgtaaca gtgaaaaatt gaaaacaacc tggaagtcca 1500

 gtgatgggaa aatgagtatg tttctgtctt agattgggga acccaaagca 1550

 gattgcaaga ctgaaatttc agtgaaagca gtgtatttgc taggtcatac 1600

 cagaaatcat caattgaggt acggagaaac tgaactgaga aggtaagaaa 1650

 agcaatttaa agtcagcgag caggttctca ttgataacaa gctccatact 1700

 gctgagatac agggaaatgg aggggggaaa gctggagtat tgatcccgcc 1750

 cccctccttg gttgtcagct ccctgtcctg tgtgtgggcg gaacatagtc 1800

 cagctgctct atagcaagtc tcaggtgttt gcagtaagaa gctgctggca 1850

 tgcacgggaa cagtgaatgc caaacactta aagcaattcg atgtttaagt 1900

 atgtaagttc tttttttttt agacagcgtt tcgctcttgt tgcccaggct 1950

 agcatgcaat ggtgtgacct cggcttactg caacctccgc cttcccagat 2000

 tcaagcgatt ctcctgcctc aggctcccaa gtagctagga ccaggtgcgc 2050

 gccaccacgc ccggctaatt tttgtatttt gtatttttag tagagatggg 2100

 gtttcaccat gttggtcagg ctagtctcga actcgtgacc gcaagcgatt 2150

 cacccacctc agcctcccaa agtgctggga ttaccggctt gagccaccac 2200

 acccggcaca tcttcattct ttttatgtag taaaaagtat aaggccacac 2250

 atggtttatt tgaagtattt tataatttaa aaaaatacag aagcaggaaa 2300

 accaattata agttcaagtg agggatgatg gttgcttgaa ccaaagggtt 2350

 gcatgtagta agaaattgtg atttaagata tattttaaag ttataagtag 2400

 caggatattc tgatggagtt tgactttggt tttgggccca gggagtttca 2450

 gatgcctttg agaaatgaat gaagtagaga gaaaataaaa gaaaaaccag 2500

 ccaggcacag tggctcacac ctgtaatccc agcgctttgg gaggctaagg 2550

 caggcagatc acttgagacc agcttgggca acatggcaaa gccccatctc 2600

 tacaaaaaac acaaaaatta gctgggcatt gtggcgcaca cctgtattcc 2650

 catctagtca ggaagctgag atggaagaat taattgagcc cacgagttca 2700

 aggctgcagt gagtcgtgat tgtgccactg cactccagcc ggggtgacag 2750

 aagagacctt gtctcgaaaa cgaatctgaa aacaatggaa ccatgccttc 2800

 ataattctag aaagttattt tcaactgata aatctatatt cacccaaata 2850

 atcaagggtg aaggtaaaat aatacatttt tagacaagca aagactcagg 2900

 ggttacctcc atgtgccctt tttagggaag ctgttggaga aaatactcca 2950

 gcaaaatgaa ggagtacaca aaccagagaa tgacatgaat ccagcaaata 3000

 ggatccaaca caggcaatat tccagctatg gagctagctt taaaaaggaa 3050

 cagtaaaaat attaatcggt tagctgggtg gaatggccca tgcctgtagt 3100

 cccagctact caggaggctc agcagcagga cgacttgagc ccaagagttc 3150

 cagaccagcc tggccacctt agtgagatcc cttctcttaa aaataataac 3200

 ttattgccag atttggggca tttggaaaga agttcattga agataaagca 3250

 aaagtaaaaa aaaaaaaaaa aaaaacaagg ggaaagggtt ggttaggcaa 3300

 tcattctagg gcagaaagaa gtacaggata ggaagagcat aatacactgt 3350

 ttttctcaac aaggagcagt atgtacacag tcataatgat gtgactgctt 3400

 agcccctaaa tatggtaact actctgggac aatatgggag gaaaagtgaa 3450

 gattgtgatg gtgtaagagc taatcctcat ctgtcatatc cagaaatcac 3500

 tatataatat ataataatga aatgactaag ttatgtgagg aaaaaaacag 3550

 aagacattgc taaaagagtt aaaagtcatt gctctggaga attaggaggg 3600

 atggggcagg ggactgttag gatgcattat aaactgaaaa gcctttttaa 3650

 aattttatgt attaatatat gcattcactt gaaaaactaa aaaaaaacaa 3700

 taatttggaa aaacccatga aggtaactaa cggaaggaaa aactaagaga 3750

 atgaaaagta tttgcctctg gaaagaacaa ctggcaggac tgttgttttc 3800

 attgtaagac ttttggagcc atttaattgt acttaaccat tttcatctat 3850

 ttctttaata agaacaattc catcttaata aagagttaca cttgttaata 3900

<210> 628
<211> 187
<212> PRT
<213> Homo sapien

<400> 628
 Met Val Gly Ser Leu Asn Cys Ile Val Ala Val Ser Gln Asn Met
   1               5                  10                  15

 Gly Ile Gly Lys Asn Gly Asp Leu Pro Trp Pro Pro Leu Arg Asn
                  20                  25                  30

 Glu Phe Arg Tyr Phe Gln Arg Met Thr Thr Thr Ser Ser Val Glu
                  35                  40                  45

 Gly Lys Gln Asn Leu Val Ile Met Gly Lys Lys Thr Trp Phe Ser
                  50                  55                  60

 Ile Pro Glu Lys Asn Arg Pro Leu Lys Gly Arg Ile Asn Leu Val
                  65                  70                  75

 Leu Ser Arg Glu Leu Lys Glu Pro Pro Gln Gly Ala His Phe Leu
                  80                  85                  90

 Ser Arg Ser Leu Asp Asp Ala Leu Lys Leu Thr Glu Gln Pro Glu
                  95                 100                 105

 Leu Ala Asn Lys Val Asp Met Val Trp Ile Val Gly Gly Ser Ser
                 110                 115                 120

 Val Tyr Lys Glu Ala Met Asn His Pro Gly His Leu Lys Leu Phe
                 125                 130                 135

 Val Thr Arg Ile Met Gln Asp Phe Glu Ser Asp Thr Phe Phe Pro
                 140                 145                 150

 Glu Ile Asp Leu Glu Lys Tyr Lys Leu Leu Pro Glu Tyr Pro Gly
                 155                 160                 165

 Val Leu Ser Asp Val Gln Glu Glu Lys Gly Ile Lys Tyr Lys Phe
                 170                 175                 180

 Glu Val Tyr Glu Lys Asn Asp
                 185

<210> 629
<211> 702
<212> DNA
<213> Homo sapien

<400> 629
 aggaagccga ctaggcgaat tcacttactg accggcctgg gctgctctga 50

 gacatggagg aagccagtga aggtggagga aatgatcgtg tgcggaacct 100

 gcaaagtgag gtggagggag ttaagaatat tatgacccag aatgtggagc 150

 ggatcctggc ccggggggaa aacttggaac atctccgcaa caagacagag 200

 gatctggaag ccacatctga gcacttcaag acgacatcgc agaaggtggc 250

 tcggaaattc tggtggaaga acgtgaagat gattgtcctt atctgcgtga 300

 ttgtttttat catcatcctc ttcattgtgc tctttgccac tggtgccttc 350

 tcttaagtaa cagggaacct ctcccacctg cccttctttt cagggacaac 400

 cctccataaa tgtgtgccaa gagggtctcc tttcctgtct tcctctacag 450

 agaatgctgc tcggtcctcc tacccctctt cccgaggccc tgctgccacg 500

 ttgtatgccc cagaaggtac cttggtcccc cggaaggaga gaaaaaagag 550

 agatggactg tggctgcatt tcttgggtcc ttagagtggg ctggagagac 600

 ctagagggcc cagcatgtgg ctgggaaact gttggtggcc agtgggtaat 650

 aaagaccttt cagtatccct aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 700

 aa 702

<210> 630
<211> 100
<212> PRT
<213> Homo sapien

<400> 630
 Met Glu Glu Ala Ser Glu Gly Gly Gly Asn Asp Arg Val Arg Asn
   1               5                  10                  15

 Leu Gln Ser Glu Val Glu Gly Val Lys Asn Ile Met Thr Gln Asn
                  20                  25                  30

 Val Glu Arg Ile Leu Ala Arg Gly Glu Asn Leu Glu His Leu Arg
                  35                  40                  45

 Asn Lys Thr Glu Asp Leu Glu Ala Thr Ser Glu His Phe Lys Thr
                  50                  55                  60

 Thr Ser Gln Lys Val Ala Arg Lys Phe Trp Trp Lys Asn Val Lys
                  65                  70                  75

 Met Ile Val Leu Ile Cys Val Ile Val Phe Ile Ile Ile Leu Phe
                  80                  85                  90

 Ile Val Leu Phe Ala Thr Gly Ala Phe Ser
                  95                 100

<210> 631
<211> 3998
<212> DNA
<213> Homo sapien

<400> 631
 agcggagtca tcacaagcct gttcggcggg actgtgatgg ccagagagat 50

 gacgatctta ggatcggctg ttttgactct cctgttggcc ggctatttgg 100

 cacaacagta tttaccattg cctactccta aagtgattgg tattgatctt 150

 ggcaccacct attgttctgt tggggtgttt tttcctggca caggaaaagt 200

 aaaggtgatt ccagatgaaa atgggcatat cagcataccc agcatggtgt 250

 cttttactga caatgatgta tatgtgggat atgaaagcgt agagctggca 300

 gattcaaatc ctcaaaacac aatatatgat gccaaaagat tcataggcaa 350

 gatttttacc gcagaagagt tggaggctga aattggcaga tacccattta 400

 aggttttaaa caaaaatgga atggttgagt tttctgtgac aagtaatgag 450

 accatcacag tgtccccaga atatgttggc tctcgactat tgttgaagtt 500

 aaaggaaatg gcagaggcat atcttggaat gccagttgcc aatgctgtca 550

 tttctgtacc agcagaattt gatctaaaac agagaaattc aacaattgaa 600

 gctgctaacc ttgcaggact gaagattttg agggtaataa atgaacccac 650

 agcagcagct atggcctatg gtctccacaa ggctgacgtc ttccacgtct 700

 tggtgataga cttgggcgga ggaactctag atgtgtcttt actgaataaa 750

 caaggaggga tgtttctaac ccgagcaatg tctggaaaca ataaacttgg 800

 aggacaggac ttcaatcaga gattgcttca gtacttatat aaacagatct 850

 atcaaacata tggcttcgtg ccctctagga aagaggaaat ccacagattg 900

 agacaagctg tggaaatggt caaattaaat ctgactcttc atcaatctgc 950

 tcagttgtca gtattactaa cggtggagga gcaggacagg aaggaacctc 1000

 acagtagtga cactgaactg ccaaaagaca aactttcctc agcagatgac 1050

 catcgcgtga acagtgggtt tggacgtggc ctttctgata agaaaagtgg 1100

 agaaagtcag gttttatttg aaacagaaat atcacggaaa ctctttgata 1150

 cccttaatga agacctcttt cagaaaatac tggtacccat tcagcaagta 1200

 ttgaaagaag gccacctgga aaagactgag attgatgagg tggttttagt 1250

 tgggggctcc actcgtattc ctcggatccg tcaagtcatt caagagttct 1300

 ttggaaaaga tcccaacaca tctgtagacc ctgacctagc agtagtaacg 1350

 ggagtggcta tccaagcagg gattgatgga ggcttttggc ctctccaagt 1400

 cagtgcttta gaaattccca ataagcattt acaaaaaacc aacttcaact 1450

 gaattctgca gaaataatgg ttatttgtga acttgtctga tgatctcttc 1500

 ccatttatca gattaccttt tccacaaaag aaagtctcta aaatatcaca 1550

 gatttaccta gagggcaaca tttagataca ggaaaatttt acatagtgtt 1600

 ttgtcttagg attagacgtg accagattga tcctgtttga ttttggagag 1650

 atcctattct aacaaatact ctaaaatgat aaaattgagg tacaactctc 1700

 ttaaaagagt atggataact atattttctg gattctggag gttgataacc 1750

 atatgcactt aacattatat tctataaaca ttaagtagtg ccagttatga 1800

 gattcccagt tcttactaaa ttgtattagc aggagctggt aattacttgt 1850

 attatcacat gtaactaata atttgaacta tacttgaagg accgtgttga 1900

 tgtcaggtat ttacagtggt tggaagatag cagtattatt agcataagct 1950

 gcatacgtaa tattcagtaa ctgccatatt atataacaaa tttacattca 2000

 caaattcagt atcctgttaa gtgtcatatt cttgtaatct gcattctcca 2050

 ggagttttat gtgtttaata gatgaattta ttttatttct aaaggtattc 2100

 aaatgtttca gcaccatata gtagaaatac ccaattatat tctagttcct 2150

 ttatgtcctg tacatcattc tctgcttgga tttccattat tctgtttggt 2200

 tagagaataa aatcggtaat tgcatttgaa gaatgtgtta atgtcataat 2250

 aaagccatga ttgctatctt atttttgtta tccaagacct ttgcaaacat 2300

 tggcaaatag catcaattac ctactgtatt tgtttctttg tttatatttt 2350

 cagtaagccc tggggaatat agcatggaat tgagctacta aatggttttg 2400

 gttccgtttt acggagattt ttcctcatat ttagttttga atgaggaaaa 2450

 tgtgctcaat tataaaagct gtgttattgt tttctattat tatttttaaa 2500

 taatcacact tggactcttt tcaaacatta ggttagtttg taatgaaagc 2550

 aaaaaatttg tgaatactgg aagtaacgtg gaaatctaat gtggaagcca 2600

 ttgtggcaag gtttctacaa atcggcattt ggagcagagt tgtttgtttt 2650

 tgttgtttgt ttcctttaag aaaaaccaca gggaccaaga aagaaaatat 2700

 aacagtttga tttctgtcat acccattgta tttgaagata tatggataca 2750

 gattatatat atatatacat attttcctta atagaggaat gcttcgtatt 2800

 attcaaaaat tatatcctga tcaccttttt ttgtttttta ttgtaaagta 2850

 tctctgcttc atccattgct gaattcgata ggatgttgaa atgctggtca 2900

 ccaaaaaagg aaactgagca aattcatttc aacaacatca aaacttcagc 2950

 ttctcatagt aaaaagctga atgttactaa tatttttcat atctaaaaaa 3000

 gaattcttag caatgaaatt gctgttaaaa cacaaatttc aatcaaatac 3050

 ttttgtgtat agaaaatatg tatagtaggt agatagaaaa gtataaaatg 3100

 tttgttgaag tatcttattt tagaatgaat ggagaaatgc caaagatgaa 3150

 tccttcactg cattatgaaa atatttcaca tgttctcttg gactttatat 3200

 aaatctgtaa tagattttag aattgaaaaa ttctttgtga aggtcttcta 3250

 aaagtgttcc aatttatctc aaaatctcca tatataggat cagcttaaaa 3300

 cataaagaaa accttgaatt tctcaaatgt ttgagatgtt caagacagtc 3350

 tcttaatccg ttaatgcttt tggaaacaat tgacaaaata gggcaggcag 3400

 ctcatctcat gtcctgaagt tggaatttaa ataattccta tttgcaaatt 3450

 agaatgacag tgttggaatt tggaggcagt agttgagcat attctctagt 3500

 atatagctac acctttaata aaatgaagga atgtcttcaa tcatatttta 3550

 gtgggctatt tataaatagt cttgaagtca atttagttta tttatttaaa 3600

 agataatgca tcctgaaagg gatcatttat gaataacaat ctgaagtctt 3650

 ttcataaaaa aaattaataa actttagttg tacatttagc cagcgttatt 3700

 tgaagtatgt aacttttaaa atattaagtg tcttgtatga ttagaatatg 3750

 tgaatgagta acttattttg tatcaggaat gttttggtac tgtgttttca 3800

 ctcaaaccac tgacttaaca gatactgctg tgtataacat gtactaaata 3850

 ttacagttat tgtgcataac agattgttcc tcttatattt gtgtgtatac 3900

 aggcaattca tgttttaatg taaataaata ccattttgca gtttgttttt 3950

 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa ataaaaaaaa aaaaaaaa 3998

<210> 632
<211> 471
<212> PRT
<213> Homo sapien

<400> 632
 Met Ala Arg Glu Met Thr Ile Leu Gly Ser Ala Val Leu Thr Leu
   1               5                  10                  15

 Leu Leu Ala Gly Tyr Leu Ala Gln Gln Tyr Leu Pro Leu Pro Thr
                  20                  25                  30

 Pro Lys Val Ile Gly Ile Asp Leu Gly Thr Thr Tyr Cys Ser Val
                  35                  40                  45

 Gly Val Phe Phe Pro Gly Thr Gly Lys Val Lys Val Ile Pro Asp
                  50                  55                  60

 Glu Asn Gly His Ile Ser Ile Pro Ser Met Val Ser Phe Thr Asp
                  65                  70                  75

 Asn Asp Val Tyr Val Gly Tyr Glu Ser Val Glu Leu Ala Asp Ser
                  80                  85                  90

 Asn Pro Gln Asn Thr Ile Tyr Asp Ala Lys Arg Phe Ile Gly Lys
                  95                 100                 105

 Ile Phe Thr Ala Glu Glu Leu Glu Ala Glu Ile Gly Arg Tyr Pro
                 110                 115                 120

 Phe Lys Val Leu Asn Lys Asn Gly Met Val Glu Phe Ser Val Thr
                 125                 130                 135

 Ser Asn Glu Thr Ile Thr Val Ser Pro Glu Tyr Val Gly Ser Arg
                 140                 145                 150

 Leu Leu Leu Lys Leu Lys Glu Met Ala Glu Ala Tyr Leu Gly Met
                 155                 160                 165

 Pro Val Ala Asn Ala Val Ile Ser Val Pro Ala Glu Phe Asp Leu
                 170                 175                 180

 Lys Gln Arg Asn Ser Thr Ile Glu Ala Ala Asn Leu Ala Gly Leu
                 185                 190                 195

 Lys Ile Leu Arg Val Ile Asn Glu Pro Thr Ala Ala Ala Met Ala
                 200                 205                 210

 Tyr Gly Leu His Lys Ala Asp Val Phe His Val Leu Val Ile Asp
                 215                 220                 225

 Leu Gly Gly Gly Thr Leu Asp Val Ser Leu Leu Asn Lys Gln Gly
                 230                 235                 240

 Gly Met Phe Leu Thr Arg Ala Met Ser Gly Asn Asn Lys Leu Gly
                 245                 250                 255

 Gly Gln Asp Phe Asn Gln Arg Leu Leu Gln Tyr Leu Tyr Lys Gln
                 260                 265                 270

 Ile Tyr Gln Thr Tyr Gly Phe Val Pro Ser Arg Lys Glu Glu Ile
                 275                 280                 285

 His Arg Leu Arg Gln Ala Val Glu Met Val Lys Leu Asn Leu Thr
                 290                 295                 300

 Leu His Gln Ser Ala Gln Leu Ser Val Leu Leu Thr Val Glu Glu
                 305                 310                 315

 Gln Asp Arg Lys Glu Pro His Ser Ser Asp Thr Glu Leu Pro Lys
                 320                 325                 330

 Asp Lys Leu Ser Ser Ala Asp Asp His Arg Val Asn Ser Gly Phe
                 335                 340                 345

 Gly Arg Gly Leu Ser Asp Lys Lys Ser Gly Glu Ser Gln Val Leu
                 350                 355                 360

 Phe Glu Thr Glu Ile Ser Arg Lys Leu Phe Asp Thr Leu Asn Glu
                 365                 370                 375

 Asp Leu Phe Gln Lys Ile Leu Val Pro Ile Gln Gln Val Leu Lys
                 380                 385                 390

 Glu Gly His Leu Glu Lys Thr Glu Ile Asp Glu Val Val Leu Val
                 395                 400                 405

 Gly Gly Ser Thr Arg Ile Pro Arg Ile Arg Gln Val Ile Gln Glu
                 410                 415                 420

 Phe Phe Gly Lys Asp Pro Asn Thr Ser Val Asp Pro Asp Leu Ala
                 425                 430                 435

 Val Val Thr Gly Val Ala Ile Gln Ala Gly Ile Asp Gly Gly Phe
                 440                 445                 450

 Trp Pro Leu Gln Val Ser Ala Leu Glu Ile Pro Asn Lys His Leu
                 455                 460                 465

 Gln Lys Thr Asn Phe Asn
                 470

<210> 633
<211> 1333
<212> DNA
<213> Homo sapien

<400> 633
 aagccccgcg tctccgcctt gccgtccagc ctgtccttgg tgtggggtgc 50

 ttggaagtgt gagcaccctc tctggctctt tgccggcccc aagggtcgtt 100

 gcggcggccc ccgggcccag tcatcagccc tcttttccgg tgccggaact 150

 atcgtactgg tgccctagtt tcccagccgg caggcggagt gaggaggaag 200

 cggaggcgag accgcgctca acactgggga aaggaaggag gcgggccctg 250

 cgcgcagcat tttgggaaag agtggaattc tgggtgttag gcccgccatt 300

 cgcttgactc acgccttcgc cgtagcatct ttcgcagcgg accgaagaga 350

 agaaaagtag gccagagccg aactctcttc ctgccaagat gtctattggt 400

 gtgccgatta aagtactgca tgaggccgag ggccacattg tgacatgtga 450

 gacgaacacc ggtgaggtat atcgggggaa gctcattgaa gcagaggaca 500

 acatgaactg ccagatgtcc aacatcacag tcacatacag agatggccga 550

 gtggcacagc tggagcaggt atacatccgt ggcagcaaaa tccgctttct 600

 gattttgcct gacatgctga agaacgcacc catgttaaag agcatgaaaa 650

 ataaaaacca aggctcaggg gctggccgag gaaaagctgc tattctcaag 700

 gcccaagtgg ccgcaagagg aagaggacgt ggaatgggac gtggaaacat 750

 ctttcaaaag cgaagataat tttctaagtt gaacagaact ttgtcctttt 800

 ttctttcagg ttatctgagt tcattggagt gggtgcttgt gcatatatgc 850

 taggtatctt ttgccatctt tctctttaga tcaggggaaa tgtttaagct 900

 aaataaatct ggggggtttt ttgttctgtt ttgttttgtt ttctttgaga 950

 aaataaggac tttgtgttca tttgaagttt gctttggcta aattttgaca 1000

 ccctggggga tgtcctggga gaatgccagt actttgaaat agcacagcta 1050

 ttgatgagat tttaagctgc tgttcctggc cagttgcagg ttaagcccca 1100

 gaaaagttca ccttggagaa gctccgagaa cacacagatt gtgtctcatt 1150

 catcttcaga cacaggcaca tagtgtggca ctttgttcag ttaacatttg 1200

 tggagctgtc atcagctcag ctttaacaac acaggtgact ctttcccttg 1250

 ataaagtcat aggtaattca ggggctgggt gcggcggctc acgcatgtaa 1300

 tcccagcact ttgggaggcc aaggcgggcg gat 1333

<210> 634
<211> 126
<212> PRT
<213> Homo sapien

<400> 634
 Met Ser Ile Gly Val Pro Ile Lys Val Leu His Glu Ala Glu Gly
   1               5                  10                  15

 His Ile Val Thr Cys Glu Thr Asn Thr Gly Glu Val Tyr Arg Gly
                  20                  25                  30

 Lys Leu Ile Glu Ala Glu Asp Asn Met Asn Cys Gln Met Ser Asn
                  35                  40                  45

 Ile Thr Val Thr Tyr Arg Asp Gly Arg Val Ala Gln Leu Glu Gln
                  50                  55                  60

 Val Tyr Ile Arg Gly Ser Lys Ile Arg Phe Leu Ile Leu Pro Asp
                  65                  70                  75

 Met Leu Lys Asn Ala Pro Met Leu Lys Ser Met Lys Asn Lys Asn
                  80                  85                  90

 Gln Gly Ser Gly Ala Gly Arg Gly Lys Ala Ala Ile Leu Lys Ala
                  95                 100                 105

 Gln Val Ala Ala Arg Gly Arg Gly Arg Gly Met Gly Arg Gly Asn
                 110                 115                 120

 Ile Phe Gln Lys Arg Arg
                 125

<210> 635
<211> 3336
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3317
<223> Unknown base

<400> 635
 cggcggcgac tgcagtctgg agggtccaca cttgtgattc tcaatggaga 50

 gtgaaaacgc agattcataa tgaaagctag cccccgtcgg ccactgattc 100

 tcaaaagacg gaggctgccc cttcctgttc aaaatgcccc aagtgaaaca 150

 tcagaggagg aacctaagag atcccctgcc caacaggagt ctaatcaagc 200

 agaggcctcc aaggaagtgg cggagtccaa ctcttgcaag tttccagctg 250

 ggatcaagat tattaaccac cccaccatgc ccaacacgca agtagtggcc 300

 atccccaaca atgctaatat tcacagcatc atcacagcac tgactgccaa 350

 gggaaaagag agtggcagta gtgggcccaa caaattcatc ctcatcagct 400

 gtgggggagc cccaactcag cctccaggac tccggcctca aacccaaacc 450

 agctatgatg ccaaaaggac agaagtgacc ctggagacct tgggaccaaa 500

 acctgcagct agggatgtga atcttcctag accacctgga gccctttgcg 550

 agcagaaacg ggagacctgt gcagatggtg aggcagcagg ctgcactatc 600

 aacaatagcc tatccaacat ccagtggctt cgaaagatga gttctgatgg 650

 actgggctcc cgcagcatca agcaagagat ggaggaaaag gagaattgtc 700

 acctggagca gcgacaggtt aaggttgagg agccttcgag accatcagcg 750

 tcctggcaga actctgtgtc tgagcggcca ccctactctt acatggccat 800

 gatacaattc gccatcaaca gcactgagag gaagcgcatg actttgaaag 850

 acatctatac gtggattgag gaccactttc cctactttaa gcacattgcc 900

 aagccaggct ggaagaactc catccgccac aacctttccc tgcacgacat 950

 gtttgtccgg gagacgtctg ccaatggcaa ggtctccttc tggaccattc 1000

 accccagtgc caaccgctac ttgacattgg accaggtgtt taagccactg 1050

 gacccagggt ctccacaatt gcccgagcac ttggaatcac agcagaaacg 1100

 accgaatcca gagctccgcc ggaacatgac catcaaaacc gaactccccc 1150

 tgggcgcacg gcggaagatg aagccactgc taccacgggt cagctcatac 1200

 ctggtaccta tccagttccc ggtgaaccag tcactggtgt tgcagccctc 1250

 ggtgaaggtg ccattgcccc tggcggcttc cctcatgagc tcagagcttg 1300

 cccgccatag caagcgagtc cgcattgccc ccaaggtgct gctagctgag 1350

 gaggggatag ctcctctttc ttctgcagga ccagggaaag aggagaaact 1400

 cctgtttgga gaagggtttt ctcctttgct tccagttcag actatcaagg 1450

 aggaagaaat ccagcctggg gaggaaatgc cacacttagc gagacccatc 1500

 aaagtggaga gccctccctt ggaagagtgg ccctccccgg ccccatcttt 1550

 caaagaggaa tcatctcact cctgggagga ttcgtcccaa tctcccaccc 1600

 caagacccaa gaagtcctac agtgggctta ggtccccaac ccggtgtgtc 1650

 tcggaaatgc ttgtgattca acacagggag aggagggaga ggagccggtc 1700

 tcggaggaaa cagcatctac tgcctccctg tgtggatgag ccggagctgc 1750

 tcttctcaga ggggcccagt acttcccgct gggccgcaga gctcccgttc 1800

 ccagcagact cctctgaccc tgcctcccag ctcagctact cccaggaagt 1850

 gggaggacct tttaagacac ccattaagga aacgctgccc atctcctcca 1900

 ccccgagcaa atctgtcctc cccagaaccc ctgaatcctg gaggctcacg 1950

 cccccagcca aagtaggggg actggatttc agcccagtac aaacctccca 2000

 gggtgcctct gaccccttgc ctgaccccct ggggctgatg gatctcagca 2050

 ccactccctt gcaaagtgct cccccccttg aatcaccgca aaggctcctc 2100

 agttcagaac ccttagacct catctccgtc ccctttggca actcttctcc 2150

 ctcagatata gacgtcccca agccaggctc cccggagcca caggtttctg 2200

 gccttgcagc caatcgttct ctgacagaag gcctggtcct ggacacaatg 2250

 aatgacagcc tcagcaagat cctgctggac atcagctttc ctggcctgga 2300

 cgaggaccca ctgggccctg acaacatcaa ctggtcccag tttattcctg 2350

 agctacagta gagccctgcc cttgcccctg tgctcaagct gtccaccatc 2400

 ccgggcactc caaggctcag tgcaccccaa gcctctgagt gaggacagca 2450

 ggcagggact gttctgctcc tcatagctcc ctgctgcctg attatgcaaa 2500

 agtagcagtc acaccctagc cactgctggg accttgtgtt ccccaagagt 2550

 atctgattcc tctgctgtcc ctgccaggag ctgaagggtg ggaacaacaa 2600

 aggcaatggt gaaaagagat taggaacccc ccagcctgtt tccattctct 2650

 gcccagcagt ctcttacctt ccctgatctt tgcagggtgg tccgtgtaaa 2700

 tagtataaat tctccaaatt atcctctaat tataaatgta agcttatttc 2750

 cttagatcat tatccagaga ctgccagaag gtgggtagga tgacctgggg 2800

 tttcaattga cttctgttcc ttgcttttag ttttgataga agggaagacc 2850

 tgcagtgcac ggtttcttcc aggctgaggt acctggatct tgggttcttc 2900

 actgcaggga cccagacaag tggatctgct tgccagagtc ctttttgccc 2950

 ctccctgcca cctccccgtg tttccaagtc agctttcctg caagaagaaa 3000

 tcctggttaa aaaagtcttt tgtattgggt caggagttga atttggggtg 3050

 ggaggatgga tgcaactgaa gcagagtgtg ggtgcccaga tgtgcgctat 3100

 tagatgtttc tctgataatg tccccaatca taccagggag actggcattg 3150

 acgagaactc aggtggaggc ttgagaaggc cgaaagggcc cctgacctgc 3200

 ctggcttcct tagcttgccc ctcagctttg caaagagcca ccctaggccc 3250

 cagctgaccg catgggtgtg agccagcttg agaacactaa ctactcaata 3300

 aaagcgaagg tggaccnaaa aaaaaaaaaa aaaaaa 3336

<210> 636
<211> 763
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3317
<223> Unknown amino acid

<400> 636
 Met Lys Ala Ser Pro Arg Arg Pro Leu Ile Leu Lys Arg Arg Arg
   1               5                  10                  15

 Leu Pro Leu Pro Val Gln Asn Ala Pro Ser Glu Thr Ser Glu Glu
                  20                  25                  30

 Glu Pro Lys Arg Ser Pro Ala Gln Gln Glu Ser Asn Gln Ala Glu
                  35                  40                  45

 Ala Ser Lys Glu Val Ala Glu Ser Asn Ser Cys Lys Phe Pro Ala
                  50                  55                  60

 Gly Ile Lys Ile Ile Asn His Pro Thr Met Pro Asn Thr Gln Val
                  65                  70                  75

 Val Ala Ile Pro Asn Asn Ala Asn Ile His Ser Ile Ile Thr Ala
                  80                  85                  90

 Leu Thr Ala Lys Gly Lys Glu Ser Gly Ser Ser Gly Pro Asn Lys
                  95                 100                 105

 Phe Ile Leu Ile Ser Cys Gly Gly Ala Pro Thr Gln Pro Pro Gly
                 110                 115                 120

 Leu Arg Pro Gln Thr Gln Thr Ser Tyr Asp Ala Lys Arg Thr Glu
                 125                 130                 135

 Val Thr Leu Glu Thr Leu Gly Pro Lys Pro Ala Ala Arg Asp Val
                 140                 145                 150

 Asn Leu Pro Arg Pro Pro Gly Ala Leu Cys Glu Gln Lys Arg Glu
                 155                 160                 165

 Thr Cys Ala Asp Gly Glu Ala Ala Gly Cys Thr Ile Asn Asn Ser
                 170                 175                 180

 Leu Ser Asn Ile Gln Trp Leu Arg Lys Met Ser Ser Asp Gly Leu
                 185                 190                 195

 Gly Ser Arg Ser Ile Lys Gln Glu Met Glu Glu Lys Glu Asn Cys
                 200                 205                 210

 His Leu Glu Gln Arg Gln Val Lys Val Glu Glu Pro Ser Arg Pro
                 215                 220                 225

 Ser Ala Ser Trp Gln Asn Ser Val Ser Glu Arg Pro Pro Tyr Ser
                 230                 235                 240

 Tyr Met Ala Met Ile Gln Phe Ala Ile Asn Ser Thr Glu Arg Lys
                 245                 250                 255

 Arg Met Thr Leu Lys Asp Ile Tyr Thr Trp Ile Glu Asp His Phe
                 260                 265                 270

 Pro Tyr Phe Lys His Ile Ala Lys Pro Gly Trp Lys Asn Ser Ile
                 275                 280                 285

 Arg His Asn Leu Ser Leu His Asp Met Phe Val Arg Glu Thr Ser
                 290                 295                 300

 Ala Asn Gly Lys Val Ser Phe Trp Thr Ile His Pro Ser Ala Asn
                 305                 310                 315

 Arg Tyr Leu Thr Leu Asp Gln Val Phe Lys Pro Leu Asp Pro Gly
                 320                 325                 330

 Ser Pro Gln Leu Pro Glu His Leu Glu Ser Gln Gln Lys Arg Pro
                 335                 340                 345

 Asn Pro Glu Leu Arg Arg Asn Met Thr Ile Lys Thr Glu Leu Pro
                 350                 355                 360

 Leu Gly Ala Arg Arg Lys Met Lys Pro Leu Leu Pro Arg Val Ser
                 365                 370                 375

 Ser Tyr Leu Val Pro Ile Gln Phe Pro Val Asn Gln Ser Leu Val
                 380                 385                 390

 Leu Gln Pro Ser Val Lys Val Pro Leu Pro Leu Ala Ala Ser Leu
                 395                 400                 405

 Met Ser Ser Glu Leu Ala Arg His Ser Lys Arg Val Arg Ile Ala
                 410                 415                 420

 Pro Lys Val Leu Leu Ala Glu Glu Gly Ile Ala Pro Leu Ser Ser
                 425                 430                 435

 Ala Gly Pro Gly Lys Glu Glu Lys Leu Leu Phe Gly Glu Gly Phe
                 440                 445                 450

 Ser Pro Leu Leu Pro Val Gln Thr Ile Lys Glu Glu Glu Ile Gln
                 455                 460                 465

 Pro Gly Glu Glu Met Pro His Leu Ala Arg Pro Ile Lys Val Glu
                 470                 475                 480

 Ser Pro Pro Leu Glu Glu Trp Pro Ser Pro Ala Pro Ser Phe Lys
                 485                 490                 495

 Glu Glu Ser Ser His Ser Trp Glu Asp Ser Ser Gln Ser Pro Thr
                 500                 505                 510

 Pro Arg Pro Lys Lys Ser Tyr Ser Gly Leu Arg Ser Pro Thr Arg
                 515                 520                 525

 Cys Val Ser Glu Met Leu Val Ile Gln His Arg Glu Arg Arg Glu
                 530                 535                 540

 Arg Ser Arg Ser Arg Arg Lys Gln His Leu Leu Pro Pro Cys Val
                 545                 550                 555

 Asp Glu Pro Glu Leu Leu Phe Ser Glu Gly Pro Ser Thr Ser Arg
                 560                 565                 570

 Trp Ala Ala Glu Leu Pro Phe Pro Ala Asp Ser Ser Asp Pro Ala
                 575                 580                 585

 Ser Gln Leu Ser Tyr Ser Gln Glu Val Gly Gly Pro Phe Lys Thr
                 590                 595                 600

 Pro Ile Lys Glu Thr Leu Pro Ile Ser Ser Thr Pro Ser Lys Ser
                 605                 610                 615

 Val Leu Pro Arg Thr Pro Glu Ser Trp Arg Leu Thr Pro Pro Ala
                 620                 625                 630

 Lys Val Gly Gly Leu Asp Phe Ser Pro Val Gln Thr Ser Gln Gly
                 635                 640                 645

 Ala Ser Asp Pro Leu Pro Asp Pro Leu Gly Leu Met Asp Leu Ser
                 650                 655                 660

 Thr Thr Pro Leu Gln Ser Ala Pro Pro Leu Glu Ser Pro Gln Arg
                 665                 670                 675

 Leu Leu Ser Ser Glu Pro Leu Asp Leu Ile Ser Val Pro Phe Gly
                 680                 685                 690

 Asn Ser Ser Pro Ser Asp Ile Asp Val Pro Lys Pro Gly Ser Pro
                 695                 700                 705

 Glu Pro Gln Val Ser Gly Leu Ala Ala Asn Arg Ser Leu Thr Glu
                 710                 715                 720

 Gly Leu Val Leu Asp Thr Met Asn Asp Ser Leu Ser Lys Ile Leu
                 725                 730                 735

 Leu Asp Ile Ser Phe Pro Gly Leu Asp Glu Asp Pro Leu Gly Pro
                 740                 745                 750

 Asp Asn Ile Asn Trp Ser Gln Phe Ile Pro Glu Leu Gln
                 755                 760

<210> 637
<211> 1536
<212> DNA
<213> Homo sapien

<400> 637
 gggggggggg ggaccacttg gcctgcctcc gtcccgccgc gccacttggc 50

 ctgcctccgt cccgccgcgc cacttcgcct gcctccgtcc cccgcccgcc 100

 gcgccatgcc tgtggccggc tcggagctgc cgcgccggcc cttgcccccc 150

 gccgcacagg agcgggacgc cgagccgcgt ccgccgcacg gggagctgca 200

 gtacctgggg cagatccaac acatcctccg ctgcggcgtc aggaaggacg 250

 accgcacggg caccggcacc ctgtcggtat tcggcatgca ggcgcgctac 300

 agcctgagag atgaattccc tctgctgaca accaaacgtg tgttctggaa 350

 gggtgttttg gaggagttgc tgtggtttat caagggatcc acaaatgcta 400

 aagagctgtc ttccaaggga gtgaaaatct gggatgccaa tggatcccga 450

 gactttttgg acagcctggg attctccacc agagaagaag gggacttggg 500

 cccagtttat ggcttccagt ggaggcattt tggggcagaa tacagagata 550

 tggaatcaga ttattcagga cagggagttg accaactgca aagagtgatt 600

 gacaccatca aaaccaaccc tgacgacaga agaatcatca tgtgcgcttg 650

 gaatccaaga gatcttcctc tgatggcgct gcctccatgc catgccctct 700

 gccagttcta tgtggtgaac agtgagctgt cctgccagct gtaccagaga 750

 tcgggagaca tgggcctcgg tgtgcctttc aacatcgcca gctacgccct 800

 gctcacgtac atgattgcgc acatcacggg cctgaagcca ggtgacttta 850

 tacacacttt gggagatgca catatttacc tgaatcacat cgagccactg 900

 aaaattcagc ttcagcgaga acccagacct ttcccaaagc tcaggattct 950

 tcgaaaagtt gagaaaattg atgacttcaa agctgaagac tttcagattg 1000

 aagggtacaa tccgcatcca actattaaaa tggaaatggc tgtttagggt 1050

 gctttcaaag gagcttgaag gatattgtca gtctttaggg gttgggctgg 1100

 atgccgaggt aaaagttctt tttgctctaa aagaaaaagg aactaggtca 1150

 aaaatctgtc cgtgacctat cagttattaa tttttaagga tgttgccact 1200

 ggcaaatgta actgtgccag ttctttccat aataaaaggc tttgagttaa 1250

 ctcactgagg gtatctgaca atgctgaggt tatgaacaaa gtgaggagaa 1300

 tgaaatgtat gtgctcttag caaaaacatg tatgtgcatt tcaatcccac 1350

 gtacttataa agaaggttgg tgaatttcac aagctatttt tggaatattt 1400

 ttagaatatt ttaagaattt cacaagctat tccctcaaat ctgagggagc 1450

 tgagtaacac catcgatcat gatgtagagt gtggttatga actttatagt 1500

 tgttttatat gttgctataa taaagaagtg ttctgc 1536

<210> 638
<211> 313
<212> PRT
<213> Homo sapien

<400> 638
 Met Pro Val Ala Gly Ser Glu Leu Pro Arg Arg Pro Leu Pro Pro
   1               5                  10                  15

 Ala Ala Gln Glu Arg Asp Ala Glu Pro Arg Pro Pro His Gly Glu
                  20                  25                  30

 Leu Gln Tyr Leu Gly Gln Ile Gln His Ile Leu Arg Cys Gly Val
                  35                  40                  45

 Arg Lys Asp Asp Arg Thr Gly Thr Gly Thr Leu Ser Val Phe Gly
                  50                  55                  60

 Met Gln Ala Arg Tyr Ser Leu Arg Asp Glu Phe Pro Leu Leu Thr
                  65                  70                  75

 Thr Lys Arg Val Phe Trp Lys Gly Val Leu Glu Glu Leu Leu Trp
                  80                  85                  90

 Phe Ile Lys Gly Ser Thr Asn Ala Lys Glu Leu Ser Ser Lys Gly
                  95                 100                 105

 Val Lys Ile Trp Asp Ala Asn Gly Ser Arg Asp Phe Leu Asp Ser
                 110                 115                 120

 Leu Gly Phe Ser Thr Arg Glu Glu Gly Asp Leu Gly Pro Val Tyr
                 125                 130                 135

 Gly Phe Gln Trp Arg His Phe Gly Ala Glu Tyr Arg Asp Met Glu
                 140                 145                 150

 Ser Asp Tyr Ser Gly Gln Gly Val Asp Gln Leu Gln Arg Val Ile
                 155                 160                 165

 Asp Thr Ile Lys Thr Asn Pro Asp Asp Arg Arg Ile Ile Met Cys
                 170                 175                 180

 Ala Trp Asn Pro Arg Asp Leu Pro Leu Met Ala Leu Pro Pro Cys
                 185                 190                 195

 His Ala Leu Cys Gln Phe Tyr Val Val Asn Ser Glu Leu Ser Cys
                 200                 205                 210

 Gln Leu Tyr Gln Arg Ser Gly Asp Met Gly Leu Gly Val Pro Phe
                 215                 220                 225

 Asn Ile Ala Ser Tyr Ala Leu Leu Thr Tyr Met Ile Ala His Ile
                 230                 235                 240

 Thr Gly Leu Lys Pro Gly Asp Phe Ile His Thr Leu Gly Asp Ala
                 245                 250                 255

 His Ile Tyr Leu Asn His Ile Glu Pro Leu Lys Ile Gln Leu Gln
                 260                 265                 270

 Arg Glu Pro Arg Pro Phe Pro Lys Leu Arg Ile Leu Arg Lys Val
                 275                 280                 285

 Glu Lys Ile Asp Asp Phe Lys Ala Glu Asp Phe Gln Ile Glu Gly
                 290                 295                 300

 Tyr Asn Pro His Pro Thr Ile Lys Met Glu Met Ala Val
                 305                 310

<210> 639
<211> 2135
<212> DNA
<213> Homo sapien

<400> 639
 gccccaggag cccggcgggt ccgggactcc cgtccgtgcc ggtgcgggcg 50

 ccggcatgtg gctgtgggag gaccagggcg gcctcctggg ccctttctcc 100

 ttcctgctgc tagtgctgct gctggtgacg cggagcccgg tcaatgcctg 150

 cctcctcacc ggcagcctct tcgttctact gcgcgtcttc agctttgagc 200

 cggtgccctc ttgcagggcc ctgcaggtgc tcaagccccg ggaccgcatt 250

 tctgccatcg cccaccgtgg cggcagccac gacgcgcccg agaacacgct 300

 ggcggccatt cggcaggcag ctaagaatgg agcaacaggc gtggagttgg 350

 acattgagtt tacttctgac gggattcctg tcttaatgca cgataacaca 400

 gtagatagga cgactgatgg gactgggcga ttgtgtgatt tgacatttga 450

 acaaattagg aagctgaatc ctgcagcaaa ccacagactc aggaatgatt 500

 tccctgatga aaagatccct accctaaggg aagctgttgc agagtgccta 550

 aaccataacc tcacaatctt ctttgatgtc aaaggccatg cacacaaggc 600

 tactgaggct ctaaagaaaa tgtatatgga atttcctcaa ctgtataata 650

 atagtgtggt ctgttctttc ttgccagaag ttatctacaa gatgagacaa 700

 acagatcggg atgtaataac agcattaact cacagacctt ggagcctaag 750

 ccatacagga gatgggaaac cacgctatga tactttctgg aaacatttta 800

 tatttgttat gatggacatt ttgctcgatt ggagcatgca taatatcttg 850

 tggtacctgt gtggaatttc agctttcctc atgcaaaagg attttgtatc 900

 cccggcctac ttgaagaagt ggtcagctaa aggaatccag gttgttggtt 950

 ggactgttaa tacctttgat gaaaagagtt actacgaatc ccatcttggt 1000

 tccagctata tcactgacag catggtagaa gactgcgaac ctcacttcta 1050

 gactttcacg gtgggacgaa acgggttcag aaactgccag gggcctcata 1100

 cagggatatc aaaataccct ttgtgctagc ccaggccctg gggaatcagg 1150

 tgactcacac aaatgcaata gttggtcact gcatttttac ctgaaccaaa 1200

 gctaaacccg gtgttgccac catgcaccat ggcatgccag agttcaacac 1250

 tgttgctctt gaaaatctgg gtctgaaaaa acgcacaaga gcccctgccc 1300

 tgccctagct gaggcacaca gggagaccca gtgaggataa gcacagattg 1350

 aattgtacaa tttgcagatg cagatgtaaa tgcatgggac atgcatgata 1400

 actcagagtt gacattttaa aacttgccac acttatttca aatatttgta 1450

 ctcagctatg ttaacatgta ctgtagacat caaacttgtg gccatactaa 1500

 taaaattatt aaaaggagca ctaaaggaaa actgtgtgcc aagcatcata 1550

 tcctaaggca tacggaattt ggggaagcca ccatgcaatc cagtgaggct 1600

 tcagtgtaca gcaaccaaaa tggtagggag gtcttgaagc caatgaggga 1650

 tttatagcat cttgaataga gagctgcaaa ccaccagggg gcagagttgc 1700

 acttttccag gctttttagg aagctctgca acagatgtga tctgatcata 1750

 ggcaattaga actggaagaa acttccaaaa atatctaggt ttgtcctcat 1800

 tttacaaatg aggaaactaa actctgtgga agggaagggg ttgcctcaaa 1850

 agtcacagct tagctgggca cagtggctca tgccgataat cccagcaatt 1900

 cagaaagctg aggcaggagg attacttgag gccagactgg gcaatatagc 1950

 aagaccccat ctctaaaaaa ttaggcatgg tggtgcatgc ctgtattccc 2000

 agctactcag gaggttgagg tgggaggatc acttgagccc agaagttcaa 2050

 ggctgcaatg agccatgatt acaccacggc actacaacct tggtggcaca 2100

 gtgagaacct gactcttaaa aaaaaaaaaa aaaaa 2135

<210> 640
<211> 331
<212> PRT
<213> Homo sapien

<400> 640
 Met Trp Leu Trp Glu Asp Gln Gly Gly Leu Leu Gly Pro Phe Ser
   1               5                  10                  15

 Phe Leu Leu Leu Val Leu Leu Leu Val Thr Arg Ser Pro Val Asn
                  20                  25                  30

 Ala Cys Leu Leu Thr Gly Ser Leu Phe Val Leu Leu Arg Val Phe
                  35                  40                  45

 Ser Phe Glu Pro Val Pro Ser Cys Arg Ala Leu Gln Val Leu Lys
                  50                  55                  60

 Pro Arg Asp Arg Ile Ser Ala Ile Ala His Arg Gly Gly Ser His
                  65                  70                  75

 Asp Ala Pro Glu Asn Thr Leu Ala Ala Ile Arg Gln Ala Ala Lys
                  80                  85                  90

 Asn Gly Ala Thr Gly Val Glu Leu Asp Ile Glu Phe Thr Ser Asp
                  95                 100                 105

 Gly Ile Pro Val Leu Met His Asp Asn Thr Val Asp Arg Thr Thr
                 110                 115                 120

 Asp Gly Thr Gly Arg Leu Cys Asp Leu Thr Phe Glu Gln Ile Arg
                 125                 130                 135

 Lys Leu Asn Pro Ala Ala Asn His Arg Leu Arg Asn Asp Phe Pro
                 140                 145                 150

 Asp Glu Lys Ile Pro Thr Leu Arg Glu Ala Val Ala Glu Cys Leu
                 155                 160                 165

 Asn His Asn Leu Thr Ile Phe Phe Asp Val Lys Gly His Ala His
                 170                 175                 180

 Lys Ala Thr Glu Ala Leu Lys Lys Met Tyr Met Glu Phe Pro Gln
                 185                 190                 195

 Leu Tyr Asn Asn Ser Val Val Cys Ser Phe Leu Pro Glu Val Ile
                 200                 205                 210

 Tyr Lys Met Arg Gln Thr Asp Arg Asp Val Ile Thr Ala Leu Thr
                 215                 220                 225

 His Arg Pro Trp Ser Leu Ser His Thr Gly Asp Gly Lys Pro Arg
                 230                 235                 240

 Tyr Asp Thr Phe Trp Lys His Phe Ile Phe Val Met Met Asp Ile
                 245                 250                 255

 Leu Leu Asp Trp Ser Met His Asn Ile Leu Trp Tyr Leu Cys Gly
                 260                 265                 270

 Ile Ser Ala Phe Leu Met Gln Lys Asp Phe Val Ser Pro Ala Tyr
                 275                 280                 285

 Leu Lys Lys Trp Ser Ala Lys Gly Ile Gln Val Val Gly Trp Thr
                 290                 295                 300

 Val Asn Thr Phe Asp Glu Lys Ser Tyr Tyr Glu Ser His Leu Gly
                 305                 310                 315

 Ser Ser Tyr Ile Thr Asp Ser Met Val Glu Asp Cys Glu Pro His
                 320                 325                 330

 Phe


<210> 641
<211> 2701
<212> DNA
<213> Homo sapien

<400> 641
 ccgccgtagc gcgtcttggg tctcccggct gccgctgctg ccgccgccgc 50

 ctcgggtcgt ggagccagga gcgacgtcac cgccatggca ggcatcaaag 100

 ctttgattag tttgtccttt ggaggagcaa tcggactgat gtttttgatg 150

 cttggatgtg cccttccaat atacaacaaa tactggcccc tctttgttct 200

 atttttttac atcctttcac ctattccata ctgcatagca agaagattag 250

 tggatgatac agatgctatg agtaacgctt gtaaggaact tgccatcttt 300

 cttacaacgg gcattgtcgt gtcagctttt ggactcccta ttgtatttgc 350

 cagagcacat ctgattgagt ggggagcttg tgcacttgtt ctcacaggaa 400

 acacagtcat ctttgcaact atactaggct ttttcttggt ctttggaagc 450

 aaggacgact tcagctggca gcagtggtga aaagaaatta ctgaactatt 500

 gtcaaatgga cttcctgtca tttgttggcc attcacgcac acaggagatg 550

 gggcagttaa tgctgaatgg tatagcaagc ctcttggggg tattttaggt 600

 gctcccttct cacttttatt gtaagcatac tattttcaca gagacttgct 650

 gaaggattaa aaggattttc tcttttggaa aagcttgact gatttcacac 700

 ttatctatag tatgcttttt gtggtgtcct gctgaattta aatatttatg 750

 tgtttttcct gttaggttga ttttttttgg aatcaatatg caatgttaaa 800

 cactttttta atgtaatcat ttgcattggt taggaattca gaattccgcc 850

 ggctctatta ctggtcaagt acatcttttc tcttaaaatt atttagcctc 900

 cattattaca aaaaattata aaaataagtt ttcagtcagt caggatgaca 950

 tcactcccaa tgttatgcag acatacagac ggttggcata cgttatagac 1000

 tgtatactca gtgcaaatat agctgcattt atacctcaga ggggccaagt 1050

 gttaatgccc atgccctccg ttaagggttg ttggttttac tggtagacag 1100

 atgttttgtg gattgaaaat tattttatgg aattgctaca gaggagtgct 1150

 tttcttctca attgttagaa gaatttatgt taaactttaa ggtaagggtg 1200

 taaaaacatt tttgagataa ggtttttatt tatgtttatt attgttagag 1250

 tgagttgcaa tgtgggaaga aatgacattg aaattccagt ttttgaatcc 1300

 tgtttctatt tataagtgaa atttgtgatc tcctatcaac ctttcatgtt 1350

 ttaccctgtt aaaatggaca tacatggaac cactactgat gagggacagt 1400

 tgtatgtttg catcatatat gccagaaaac cttcctctgc ttcctccttt 1450

 tgacttattt ggtatgttgt atatattaca taaaataact tttcaaatat 1500

 agtttaataa cacttagaag tgtttactta cctggaaaat aattgctatg 1550

 ccgtacattc agagtgcccc ctcccctgca aggccttgcc atgattaaca 1600

 agtaacttgt tagtcttaca gataattcat gcattaacag tttaagattt 1650

 agaccatggt aatagtagtt cttattctct aaggttatat catatgtaat 1700

 ttaaaagtat ttttaagcca agtttcctgt atacctctga actgttttga 1750

 ttttgagttc atcatgatag atctgctgtt tccttataaa aggcatttgt 1800

 tgtgtgagtt aatgcaaagt agccaagtcc agctatatag cagcttcaga 1850

 aacatacctg accaaaaaat tcccagtaac caggcatgat caatttatag 1900

 tggtcgttta catctaataa ttatcaggac ttttttcagg agtgggttat 1950

 aaaaacattc aagttggtct gacagtattt tgttaaggat atttgtttgt 2000

 atgtttattc agtatactta cataaaaatt atttcgccat cagccaaaac 2050

 tcagtaatca tgacagctgt ctgttgtttt atgaagttta tttctcaaga 2100

 aaatgggaat aaatttggga tttgttcagc ttttttacta aagatgccta 2150

 aagccacagg ttttattgcc taacttaagc catgactttt agatatgaga 2200

 tgacgggaag caggacgaaa tatcggcgtg tggctggagc cttcccactg 2250

 gaggctgaaa gtggcttgtg gtattataat gttcagattt caagaggaag 2300

 gtgcaggtac acatgagtta gagagctggt gagacagttg ggaactcttt 2350

 gtgcttgtga tctactggac tttttttttg caggaagtgc attctctggt 2400

 ccttccctat tttctgttct ggatgtcagt gcagtgcact gctactgttt 2450

 tatccacttg gccacagact ttttctaaca gctgcgtatt atttctatat 2500

 actaattgca ttggcagcat tgtgtctttg accttgtata ctagcttgac 2550

 atagtgctgt ctctgatttc taggctagtt acttgagata tgaattttcc 2600

 atagaatatg cactgataca acattaccat tcttctatgg aaagaaaact 2650

 tttgatgatg aaacaataaa gattttaaat atcaaaaaaa aaaaaaaaaa 2700

 a 2701

<210> 642
<211> 131
<212> PRT
<213> Homo sapien

<400> 642
 Met Ala Gly Ile Lys Ala Leu Ile Ser Leu Ser Phe Gly Gly Ala
   1               5                  10                  15

 Ile Gly Leu Met Phe Leu Met Leu Gly Cys Ala Leu Pro Ile Tyr
                  20                  25                  30

 Asn Lys Tyr Trp Pro Leu Phe Val Leu Phe Phe Tyr Ile Leu Ser
                  35                  40                  45

 Pro Ile Pro Tyr Cys Ile Ala Arg Arg Leu Val Asp Asp Thr Asp
                  50                  55                  60

 Ala Met Ser Asn Ala Cys Lys Glu Leu Ala Ile Phe Leu Thr Thr
                  65                  70                  75

 Gly Ile Val Val Ser Ala Phe Gly Leu Pro Ile Val Phe Ala Arg
                  80                  85                  90

 Ala His Leu Ile Glu Trp Gly Ala Cys Ala Leu Val Leu Thr Gly
                  95                 100                 105

 Asn Thr Val Ile Phe Ala Thr Ile Leu Gly Phe Phe Leu Val Phe
                 110                 115                 120

 Gly Ser Lys Asp Asp Phe Ser Trp Gln Gln Trp
                 125                 130

<210> 643
<211> 2701
<212> DNA
<213> Homo sapien

<400> 643
 ccgccgtagc gcgtcttggg tctcccggct gccgctgctg ccgccgccgc 50

 ctcgggtcgt ggagccagga gcgacgtcac cgccatggca ggcatcaaag 100

 ctttgattag tttgtccttt ggaggagcaa tcggactgat gtttttgatg 150

 cttggatgtg cccttccaat atacaacaaa tactggcccc tctttgttct 200

 atttttttac atcctttcac ctattccata ctgcatagca agaagattag 250

 tggatgatac agatgctatg agtaacgctt gtaaggaact tgccatcttt 300

 cttacaacgg gcattgtcgt gtcagctttt ggactcccta ttgtatttgc 350

 cagagcacat ctgattgagt ggggagcttg tgcacttgtt ctcacaggaa 400

 acacagtcat ctttgcaact atactaggct ttttcttggt ctttggaagc 450

 aaggacgact tcagctggca gcagtggtga aaagaaatta ctgaactatt 500

 gtcaaatgga cttcctgtca tttgttggcc attcacgcac acaggagatg 550

 gggcagttaa tgctgaatgg tatagcaagc ctcttggggg tattttaggt 600

 gctcccttct cacttttatt gtaagcatac tattttcaca gagacttgct 650

 gaaggattaa aaggattttc tcttttggaa aagcttgact gatttcacac 700

 ttatctatag tatgcttttt gtggtgtcct gctgaattta aatatttatg 750

 tgtttttcct gttaggttga ttttttttgg aatcaatatg caatgttaaa 800

 cactttttta atgtaatcat ttgcattggt taggaattca gaattccgcc 850

 ggctctatta ctggtcaagt acatcttttc tcttaaaatt atttagcctc 900

 cattattaca aaaaattata aaaataagtt ttcagtcagt caggatgaca 950

 tcactcccaa tgttatgcag acatacagac ggttggcata cgttatagac 1000

 tgtatactca gtgcaaatat agctgcattt atacctcaga ggggccaagt 1050

 gttaatgccc atgccctccg ttaagggttg ttggttttac tggtagacag 1100

 atgttttgtg gattgaaaat tattttatgg aattgctaca gaggagtgct 1150

 tttcttctca attgttagaa gaatttatgt taaactttaa ggtaagggtg 1200

 taaaaacatt tttgagataa ggtttttatt tatgtttatt attgttagag 1250

 tgagttgcaa tgtgggaaga aatgacattg aaattccagt ttttgaatcc 1300

 tgtttctatt tataagtgaa atttgtgatc tcctatcaac ctttcatgtt 1350

 ttaccctgtt aaaatggaca tacatggaac cactactgat gagggacagt 1400

 tgtatgtttg catcatatat gccagaaaac cttcctctgc ttcctccttt 1450

 tgacttattt ggtatgttgt atatattaca taaaataact tttcaaatat 1500

 agtttaataa cacttagaag tgtttactta cctggaaaat aattgctatg 1550

 ccgtacattc agagtgcccc ctcccctgca aggccttgcc atgattaaca 1600

 agtaacttgt tagtcttaca gataattcat gcattaacag tttaagattt 1650

 agaccatggt aatagtagtt cttattctct aaggttatat catatgtaat 1700

 ttaaaagtat ttttaagcca agtttcctgt atacctctga actgttttga 1750

 ttttgagttc atcatgatag atctgctgtt tccttataaa aggcatttgt 1800

 tgtgtgagtt aatgcaaagt agccaagtcc agctatatag cagcttcaga 1850

 aacatacctg accaaaaaat tcccagtaac caggcatgat caatttatag 1900

 tggtcgttta catctaataa ttatcaggac ttttttcagg agtgggttat 1950

 aaaaacattc aagttggtct gacagtattt tgttaaggat atttgtttgt 2000

 atgtttattc agtatactta cataaaaatt atttcgccat cagccaaaac 2050

 tcagtaatca tgacagctgt ctgttgtttt atgaagttta tttctcaaga 2100

 aaatgggaat aaatttggga tttgttcagc ttttttacta aagatgccta 2150

 aagccacagg ttttattgcc taacttaagc catgactttt agatatgaga 2200

 tgacgggaag caggacgaaa tatcggcgtg tggctggagc cttcccactg 2250

 gaggctgaaa gtggcttgtg gtattataat gttcagattt caagaggaag 2300

 gtgcaggtac acatgagtta gagagctggt gagacagttg ggaactcttt 2350

 gtgcttgtga tctactggac tttttttttg caggaagtgc attctctggt 2400

 ccttccctat tttctgttct ggatgtcagt gcagtgcact gctactgttt 2450

 tatccacttg gccacagact ttttctaaca gctgcgtatt atttctatat 2500

 actaattgca ttggcagcat tgtgtctttg accttgtata ctagcttgac 2550

 atagtgctgt ctctgatttc taggctagtt acttgagata tgaattttcc 2600

 atagaatatg cactgataca acattaccat tcttctatgg aaagaaaact 2650

 tttgatgatg aaacaataaa gattttaaat atcaaaaaaa aaaaaaaaaa 2700

 a 2701

<210> 644
<211> 131
<212> PRT
<213> Homo sapien

<400> 644
 Met Ala Gly Ile Lys Ala Leu Ile Ser Leu Ser Phe Gly Gly Ala
   1               5                  10                  15

 Ile Gly Leu Met Phe Leu Met Leu Gly Cys Ala Leu Pro Ile Tyr
                  20                  25                  30

 Asn Lys Tyr Trp Pro Leu Phe Val Leu Phe Phe Tyr Ile Leu Ser
                  35                  40                  45

 Pro Ile Pro Tyr Cys Ile Ala Arg Arg Leu Val Asp Asp Thr Asp
                  50                  55                  60

 Ala Met Ser Asn Ala Cys Lys Glu Leu Ala Ile Phe Leu Thr Thr
                  65                  70                  75

 Gly Ile Val Val Ser Ala Phe Gly Leu Pro Ile Val Phe Ala Arg
                  80                  85                  90

 Ala His Leu Ile Glu Trp Gly Ala Cys Ala Leu Val Leu Thr Gly
                  95                 100                 105

 Asn Thr Val Ile Phe Ala Thr Ile Leu Gly Phe Phe Leu Val Phe
                 110                 115                 120

 Gly Ser Lys Asp Asp Phe Ser Trp Gln Gln Trp
                 125                 130

<210> 645
<211> 2758
<212> DNA
<213> Homo sapien

<400> 645
 ctatccgcgc gcgtcgccgg cccagtcctg tcgctgacgg gaggatctga 50

 agccggccgc aggtcaaaga gtaaaatgaa gtacattctg gttactggtg 100

 gtgttatatc aggaattgga aaaggaatca ttgccagcag tgtgggcaca 150

 atactcaagt catgtggttt acatgtaact tcaatcaaaa ttgaccccta 200

 cattaacatt gatgcaggaa cattctctcc ttatgagcat ggtgaggttt 250

 ttgtgctgga tgatggtggg gaagtagacc ttgacctggg taactatgag 300

 cggttccttg acatccgcct caccaaggac aataatctga ccactggaaa 350

 gatataccag tatgtcatta acaaggaacg gaaaggagat tacttgggga 400

 aaactgtcca agttgtccct catatcacag atgcaatcca ggagtgggtg 450

 atgagacagg cgttaatacc tgtagatgaa gatggcctgg aacctcaagt 500

 gtgtgttatt gagcttggtg gaaccgtggg ggacatagaa agcatgccct 550

 ttattgaggc cttccgtcag ttccaattca aggtcaaaag agagaacttt 600

 tgtaacatcc acgtcagtct agttccccag ccaagttcaa caggggaaca 650

 gaagactaaa cctacccaga atagtgttcg ggaacttaga ggacttgggc 700

 tttccccaga tctggttgta tgcaggtgct caaatccact tgacacatca 750

 gtgaaggaga aaatatcaat gttctgccat gttgagcctg aacaagtgat 800

 ctgtgtccac gatgtctcat ccatctaccg agtccccttg ttgttagagg 850

 agcaaggggt tgtagattat tttcttcgaa gacttgacct tcctattgag 900

 aggcagccaa gaaaaatgct gatgaaatgg aaagagatgg ctgacagata 950

 tgatcgcttg ctggagacct gctctattgc ccttgtggcg aaatacaccg 1000

 agttctcaga ctcctatgcc tctgtcatta aggctctgga gcattctgca 1050

 ctggccatca accacaaatt ggaaatcaag tacatagatt ctgcggactt 1100

 ggagcccatc acctcgcaag aagagcccgt gcgctaccac gaagcttggc 1150

 agaagctctg tagtgctcat ggagtgctgg ttccaggagg atttggtgtt 1200

 cgaggaacag aaggaaaaat ccaagcaatt gcctgggctc ggaatcagaa 1250

 aaagcctttt ttgggcgtgt gcttagggat gcagttggca gtggttgaat 1300

 tctcaagaaa cgtgctggga tggcaagatg ccaattctac agagtttgac 1350

 cctacgacca gtcatcccgt ggtcgtagac atgccagaac acaacccagg 1400

 gcagatgggc ggaaccatga ggctgggcaa gaggagaacc ctgttccaga 1450

 ccaagaactc agtcatgagg aaactctatg gagacgcaga ctacttggaa 1500

 gagaggcacc gccaccgatt tgaggtgaat ccagtctgga aaaagtgttt 1550

 ggaagaacaa ggcttgaagt ttgttggcca agatgttgaa ggagagagaa 1600

 tggaaattgt ggagttagaa gatcatccct tttttgttgg ggttcagtac 1650

 caccctgagt tcctgtccag gcctatcaag ccctccccac catactttgg 1700

 cctcctcctg gcctctgtgg ggcggctctc acattacctc cagaaaggct 1750

 gcaggctctc acccagggac acctatagtg acaggagtgg aagcagctcc 1800

 cctgactctg aaatcaccga actgaagttt ccatcaataa atcatgactg 1850

 atcttgtagc ggatgattct tcaagagacc cttcaaactt gggtagagtt 1900

 tacagctctg actttacact cggctttgga gactttcttt aaattatgtt 1950

 tttattaaga ttattttatt atgcggaaag gtatttggga aacttgtcac 2000

 ttgcatgtcc catcacgtgt actggctcct ctgtggtgtc tgcctgttgc 2050

 gtgacactct ccttgcagtt cttgagttgc ggcagaacat cgcgatggga 2100

 accgatggtg ggtggggctg cagatgtccc catcggtcac cttgtttctc 2150

 aactacctcg catcattgca gatcgtagcg cgttgcctgt cgctttccct 2200

 tggataccta gaccgttata aagtgtgcca catggactta ccgagcatgg 2250

 agagaggatt ttagctagga tttgaacact tggtgctggg aacctcaggg 2300

 tattgcttgc cactaagcca tgaaaccaga gacaaaatct ctatactgcc 2350

 ctgagttggg gggaattctc agtgccaact gtggctggtc ctcattcaaa 2400

 gggacggtca gtttggtgtc aacatgaaac accaagatgt ctgtctctga 2450

 agcgtgattt taaaatcccc atgcctgtgc gtgcgcttcc tatttctagg 2500

 gctgggaaac actccttgca tcaaggggtc acttacagaa caaagaatct 2550

 tttgggggaa acttcctcta aaaccctctc atatatagac agctttgact 2600

 ggagggtcca tttttcttcc aggatggtgt tactgcagtt gaagggcaat 2650

 atgaagttac tttcttaatg tgacctagca ataggcatag ctacgtggca 2700

 ctatattctg gccagactcg atgtgtactc taacttaaga aataaatcag 2750

 taaggcag 2758

<210> 646
<211> 591
<212> PRT
<213> Homo sapien

<400> 646
 Met Lys Tyr Ile Leu Val Thr Gly Gly Val Ile Ser Gly Ile Gly
   1               5                  10                  15

 Lys Gly Ile Ile Ala Ser Ser Val Gly Thr Ile Leu Lys Ser Cys
                  20                  25                  30

 Gly Leu His Val Thr Ser Ile Lys Ile Asp Pro Tyr Ile Asn Ile
                  35                  40                  45

 Asp Ala Gly Thr Phe Ser Pro Tyr Glu His Gly Glu Val Phe Val
                  50                  55                  60

 Leu Asp Asp Gly Gly Glu Val Asp Leu Asp Leu Gly Asn Tyr Glu
                  65                  70                  75

 Arg Phe Leu Asp Ile Arg Leu Thr Lys Asp Asn Asn Leu Thr Thr
                  80                  85                  90

 Gly Lys Ile Tyr Gln Tyr Val Ile Asn Lys Glu Arg Lys Gly Asp
                  95                 100                 105

 Tyr Leu Gly Lys Thr Val Gln Val Val Pro His Ile Thr Asp Ala
                 110                 115                 120

 Ile Gln Glu Trp Val Met Arg Gln Ala Leu Ile Pro Val Asp Glu
                 125                 130                 135

 Asp Gly Leu Glu Pro Gln Val Cys Val Ile Glu Leu Gly Gly Thr
                 140                 145                 150

 Val Gly Asp Ile Glu Ser Met Pro Phe Ile Glu Ala Phe Arg Gln
                 155                 160                 165

 Phe Gln Phe Lys Val Lys Arg Glu Asn Phe Cys Asn Ile His Val
                 170                 175                 180

 Ser Leu Val Pro Gln Pro Ser Ser Thr Gly Glu Gln Lys Thr Lys
                 185                 190                 195

 Pro Thr Gln Asn Ser Val Arg Glu Leu Arg Gly Leu Gly Leu Ser
                 200                 205                 210

 Pro Asp Leu Val Val Cys Arg Cys Ser Asn Pro Leu Asp Thr Ser
                 215                 220                 225

 Val Lys Glu Lys Ile Ser Met Phe Cys His Val Glu Pro Glu Gln
                 230                 235                 240

 Val Ile Cys Val His Asp Val Ser Ser Ile Tyr Arg Val Pro Leu
                 245                 250                 255

 Leu Leu Glu Glu Gln Gly Val Val Asp Tyr Phe Leu Arg Arg Leu
                 260                 265                 270

 Asp Leu Pro Ile Glu Arg Gln Pro Arg Lys Met Leu Met Lys Trp
                 275                 280                 285

 Lys Glu Met Ala Asp Arg Tyr Asp Arg Leu Leu Glu Thr Cys Ser
                 290                 295                 300

 Ile Ala Leu Val Ala Lys Tyr Thr Glu Phe Ser Asp Ser Tyr Ala
                 305                 310                 315

 Ser Val Ile Lys Ala Leu Glu His Ser Ala Leu Ala Ile Asn His
                 320                 325                 330

 Lys Leu Glu Ile Lys Tyr Ile Asp Ser Ala Asp Leu Glu Pro Ile
                 335                 340                 345

 Thr Ser Gln Glu Glu Pro Val Arg Tyr His Glu Ala Trp Gln Lys
                 350                 355                 360

 Leu Cys Ser Ala His Gly Val Leu Val Pro Gly Gly Phe Gly Val
                 365                 370                 375

 Arg Gly Thr Glu Gly Lys Ile Gln Ala Ile Ala Trp Ala Arg Asn
                 380                 385                 390

 Gln Lys Lys Pro Phe Leu Gly Val Cys Leu Gly Met Gln Leu Ala
                 395                 400                 405

 Val Val Glu Phe Ser Arg Asn Val Leu Gly Trp Gln Asp Ala Asn
                 410                 415                 420

 Ser Thr Glu Phe Asp Pro Thr Thr Ser His Pro Val Val Val Asp
                 425                 430                 435

 Met Pro Glu His Asn Pro Gly Gln Met Gly Gly Thr Met Arg Leu
                 440                 445                 450

 Gly Lys Arg Arg Thr Leu Phe Gln Thr Lys Asn Ser Val Met Arg
                 455                 460                 465

 Lys Leu Tyr Gly Asp Ala Asp Tyr Leu Glu Glu Arg His Arg His
                 470                 475                 480

 Arg Phe Glu Val Asn Pro Val Trp Lys Lys Cys Leu Glu Glu Gln
                 485                 490                 495

 Gly Leu Lys Phe Val Gly Gln Asp Val Glu Gly Glu Arg Met Glu
                 500                 505                 510

 Ile Val Glu Leu Glu Asp His Pro Phe Phe Val Gly Val Gln Tyr
                 515                 520                 525

 His Pro Glu Phe Leu Ser Arg Pro Ile Lys Pro Ser Pro Pro Tyr
                 530                 535                 540

 Phe Gly Leu Leu Leu Ala Ser Val Gly Arg Leu Ser His Tyr Leu
                 545                 550                 555

 Gln Lys Gly Cys Arg Leu Ser Pro Arg Asp Thr Tyr Ser Asp Arg
                 560                 565                 570

 Ser Gly Ser Ser Ser Pro Asp Ser Glu Ile Thr Glu Leu Lys Phe
                 575                 580                 585

 Pro Ser Ile Asn His Asp
                 590

<210> 647
<211> 6888
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4245-4279
<223> Unknown base

<400> 647
 cggaggagcg cgcggttgcc gggcgggacg ggaaccgggt ctgcgcgcga 50

 gccgggcggt gggcgcggac agggccgagg gcgcccggga gccgtgtcag 100

 gcggcggcga ggagcgggcg cgccgggcgc ggggagccgt cggcggccgc 150

 tcgctgcggg gacaccccgg tgaatgagct ctcgccgcca ggcgcacggc 200

 gtaggggagc ctcgcagtgc ggcggcgtgc ggcggcggct cggggggcga 250

 ggcgggccgc ctgttcccgg ggaaggaggc gcgggcgtct gagcgaggcc 300

 gggcgcggcg gccttctctc acgcgccccc cgagccagcg cccgcctccc 350

 gcgcccgcct ctcttctccc gtcggcccag actatccgct cccaccgcgc 400

 cccccggccc acctggtggc cccggccctg gccgccgccc ccgcggcggt 450

 tcccggagct cgtcccggac gcgcgcccgg gcggcggggg ctcggcggcc 500

 accgctgcct cgggggagcg agggcgggag ggtgtgtgtg cgcgctgtga 550

 gcagggggtg ccggcggggc tgcagcggag gcactttgga agaatgactc 600

 tggagtccat catggcgtgc tgcctgagcg aggaggccaa ggaagcccgg 650

 cggatcaacg acgagatcga gcggcagctc cgcagggaca agcgggacgc 700

 ccgccgggag ctcaagctgc tgctgctcgg gacaggagag agtggcaaga 750

 gtacgtttat caagcagatg agaatcatcc atgggtcagg atactctgat 800

 gaagataaaa ggggcttcac caagctggtg tatcagaaca tcttcacggc 850

 catgcaggcc atgatcagag ccatggacac actcaagatc ccatacaagt 900

 atgagcacaa taaggctcat gcacaattag ttcgagaagt tgatgtggag 950

 aaggtgtctg cttttgagaa tccatatgta gatgcaataa agagtttatg 1000

 gaatgatcct ggaatccagg aatgctatga tagacgacga gaatatcaat 1050

 tatctgactc taccaaatac tatcttaatg acttggaccg cgtagctgac 1100

 cctgcctacc tgcctacgca acaagatgtg cttagagttc gagtccccac 1150

 cacagggatc atcgaatacc cctttgactt acaaagtgtc attttcagaa 1200

 tggtcgatgt agggggccaa aggtcagaga gaagaaaatg gatacactgc 1250

 tttgaaaatg tcacctctat catgtttcta gtagcgctta gtgaatatga 1300

 tcaagttctc gtggagtcag acaatgagaa ccgaatggag gaaagcaagg 1350

 ctctctttag aacaattatc acatacccct ggttccagaa ctcctcggtt 1400

 attctgttct taaacaagaa agatcttcta gaggagaaaa tcatgtattc 1450

 ccatctagtc gactacttcc cagaatatga tggaccccag agagatgccc 1500

 aggcagcccg agaattcatt ctgaagatgt tcgtggacct gaacccagac 1550

 agtgacaaaa ttatctactc ccacttcacg tgcgccacag acaccgagaa 1600

 tatccgcttt gtctttgctg ccgtcaagga caccatcctc cagttgaacc 1650

 tgaaggagta caatctggtc taattgtgcc tcctagacac ccgccctgcc 1700

 cttccctggt gggctattga agatacacaa gagggactgt atttctgtgg 1750

 aaaacaattt gcataatact aatttattgc cgtcctggac tctgtgtgag 1800

 cgtgtccaca gagtttgtag taaatattat gattttattt aaactattca 1850

 gaggaaaaac agaggatgct gaagtacagt cccagcacat ttcctctcta 1900

 tctttttttt aggcaaaacc ttgtgactca gtgtatttta aattctcagt 1950

 catgcactca caaagataag acttgtttct ttctgtctct ctctcttttt 2000

 cttttctatg gagcaaaaca aagctgattt cccttttttc ttcccccgct 2050

 aattcatacc tccctcctga tgtttttccc aggttacaat ggcctttatc 2100

 ctagttccat tcttggtcaa gtttttctct caaatgatac agtcaggaca 2150

 caccgttcga tttaagccat catcagctta atttaagttt gtagtttttg 2200

 ctgaaggatt atatgtatta atacttacgg ttttaaatgt gttgctttgg 2250

 atacacacat agtttctttt ttaatagaat atactgtctt gtctcacttt 2300

 ggactgggac agtggatgcc catctaaaag ttaagtgtca tttcttttag 2350

 atgtttacct tcagccatag cttgattgct cagagaaata tgcagaaggc 2400

 aggatcaaag acacacagga gtcctttctt ttgaaatgcc acgtgccatt 2450

 gtctttcctc ccttctttgc ttctttttct taccctctct ttcaattgca 2500

 gatgccaaaa aagatgccaa cagacactac attaccctaa tggctgctac 2550

 ccagaacctt tttataggtt gttcttaatt tttttgttgt tgttgttcaa 2600

 gcttttcctt tctttttttt cttagtgttt gggccacgat tttaaaatga 2650

 cttttattat gggtatgtgt tgccaaagct ggctttttgt caaataaaat 2700

 gaatacgaac ttaaaaaata aaagctggta tcttaaaatg taagagagta 2750

 agactgtgaa gcctaaaatg actggctgag aatgaaccag aaatgccatt 2800

 tgccaaacag ttgtaactag aaatttgatt ctcacagtcc attcttttct 2850

 ttgtccttaa gatgacattg ttagtgttca cgtcccatgt tcagtgtcca 2900

 aaccggcaat gtaaaaagta tcctgtgtgg cttaacagga aatctgttta 2950

 tgtctcttta tttgaaacca gttttactct cagtggttct ttaagttcaa 3000

 tgaagtctgc caggaacatt ggttggtagt attattccga cacctttaat 3050

 ttccaaaatc tgaagttcct gctagtttac caccttcatg atcttcttga 3100

 actggtaact gattaggttg aacttatgga agatttgtgg acttaactca 3150

 aaagtaacct ctcagtgttc tatagaacat gtatttgtgt aactgaacct 3200

 accaggagaa atgtttggaa ttctatatgt gcaatttttc aacaaatgca 3250

 aaaaaaatac agcacatgta ttgacaagct tctgtcaagc agcttgagtt 3300

 gaaatttgat ttaagaaaat aaatcatgat tgttcaaagc tgctgggacg 3350

 ttagaattag gccatgatac tggtctcatt ttaactacag tggtatttgg 3400

 cactagtgta aacttccata taaatcactc ttttggaaca acaaaggggg 3450

 agggagaaaa atcacggcct gttaaatgag taccaaagcc gcccaacagt 3500

 aatgagatgt tctcatcctt gattctccca gcctcaaaca acacagctta 3550

 cttttttttt cccttgctca gaaagtacct gtaatttaac aaacagactg 3600

 cctgtaggta tagtgcaatt acaaatgctc taatcattgt acatacatct 3650

 ctcttgatat tgcagcatcc atactggctt tgtaatcatt aattttttgg 3700

 cagattgaat gtgctgtatt gatatgtatc tatgtaattg tattgtatgt 3750

 ctatagctaa ttcacgtttt gaataatgtt attttattta cttttttaag 3800

 agaggagaat gtaaatttgt cagtttattt ctgactaggg atattttctt 3850

 tccatttaga aaagaaggaa aaaaaaaaaa ccttactgtc atacagagcg 3900

 gtactagcgt cgtgctgtat aaaatcattt gcacattcct gagtagaggt 3950

 atactgatta taagacccaa aggtaatttc atagcaaaat acataaaatc 4000

 agtcggagct tttatacaaa catggaaacc aactttgtag aacttttgcc 4050

 atttgatcta ggattggaat atgagctttt atacaattca tattcttatt 4100

 tggcaaatgc acagtttagt attacctctc tgatggcctt tactagaaag 4150

 gcagttttag aagctattgt gatccactaa ggaaatgttt taacagctag 4200

 agaccactgc ttgcctgaaa gggcgttctt aaatttggtg cagcnnnnnn 4250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc aacatttgaa ggcctacagt 4300

 gtgtatagag aaaacctcat cacaagatca taagtgttac agttttaggg 4350

 aatcaagata ttctatttaa tagagctata gtaaatgtag tcaattaaac 4400

 ctgatctcaa agcttgaaga agctgagcaa aacagggaaa gattgttata 4450

 tttgtcttta tgaaattggg atggaatttg ctatgcagaa ttgaggtttg 4500

 tggctttgct gttcctgtag ggtgcatgac aagatccctt ctcttgagaa 4550

 aggaaaaaat tgatcaccct agcagcagtg atgcatagaa acctaatttt 4600

 agccacacca gtcaatcgaa gctaaaggat tttctttttt gtttcttcgg 4650

 ggttttattg aaggggctag gggcgggacg ggattctttt cagttttgta 4700

 taaaaacaaa gtttactcat gctttatatt atattgtgat tgcaagcgtt 4750

 ataagcgtgt gccactggcc tcctattgtt gatgcttagg taatggaggc 4800

 ctgtggtgag ttttatggtg acttgggcat gtcttattca aaaacaaaaa 4850

 cataaaacac agaaaccttt cttcagcata ccaaggcaag cagccatttc 4900

 atgactcact taacacattg cagtgtacca gtttacagat gatttttccc 4950

 tttttgcgtg acatggcagt tctaaccccc agagaattcc ttatttgtaa 5000

 attggaagtt tctactatgc cttacagagc ttaaattcag aagtttgtgc 5050

 ctcatatctg aaacaaaggg aaataacaca cccattcaaa agtaaataaa 5100

 tctcctagaa gtttttgttt ttaacatttc catataaaga gctctgttga 5150

 atgtcatgaa tagactggaa aaaaaaattt taagaacctg catatgttgt 5200

 ttactagcag atgacaacta caaaaggaat ctgaagaaca cgtaaaactt 5250

 gtattttttt ttttttggta gattaactag caggcctatt ttaaaaaggt 5300

 aattcagcta aagggcaatt tacttttttg tacttcagac tatcttgatt 5350

 gtcaaagtgt acgaactgta attttaaaat ttatactgcc acatgattgt 5400

 aaattttagt tgtcttaagt taggaattgg tgaaaagcta tttatgctgg 5450

 atttgggtca aaatgactta tttgcaaaaa aataaataat gggaagaaag 5500

 ggctgtataa tgaaatactg caagactcac atattggttg gaaatttccc 5550

 tcaaatcacc taccgattac ccttgatttc cctttgtttt cagtttctca 5600

 aaacgaatga aatgaaatat agcagaatgt taacccatat aaaaataaag 5650

 tgtacccaaa tattgtaatg tatattgctg ctcttcttca aattaaataa 5700

 gggtttaaaa ccacttaatt ggtaatcaac atctcaattg atacaaataa 5750

 ggtgtgcttg gtatacatta atattttctt ccaaagatat atctttggtt 5800

 agaaacacaa aaaaataaaa ctagtaatat tgtatgttta tctatctcta 5850

 catatttcca gcatatgtag cgttaataga tctgtcctgg taactgtgtc 5900

 tttgggattt cattttggtt ccatcaaatt aggaaaagaa atggcttagt 5950

 tgtatatgat tagctagaga tttttggagc cagacacctg ctgtttagta 6000

 gataacttag tacagaccct aaacttgtca tttgtttttc tcacagaata 6050

 gccatttcct gctgtcttcc caatgatcac tgccctttca ataacactct 6100

 tgcctctaga atcatatgtt caaagtatga atacacacct agcacatagt 6150

 aggtgctcaa atattaattt cctccttgcc ttccttatct accctgtgtc 6200

 ctccatttcc ccgtatgatt ccaacccaat atagcaaatg acatttacat 6250

 gttatgaaaa catctattgg gtaaaatcag atcttggata aagaaattct 6300

 gacttttata taagcttttg gtagacagaa aaaacagaaa ggtattcgtt 6350

 ggtagaacat ttttaagttc aggaaagaaa gctggaataa tactacgtaa 6400

 ctttgtccag gttactttga ctgaaacacg tttttggtgg atttcttttc 6450

 ctcaaagaac tctctaaatg caactccttg ctggattcct cacccatcat 6500

 cctgttggaa acccttacta gacctatgta tttagggagt tttgtcagaa 6550

 aacattttta acttgcagta tttaaaagaa tatttactgt tcctaaaatg 6600

 tcattcaaat gcatgtactg tctattgttt ggggatggga actagttttg 6650

 caaaaaacac ctaatgttgt ataataatgc cccaatgatc ttgctggtta 6700

 aaaatacagt atttttggcc ataattttgt actatagtat tcttcattgt 6750

 tgagttttgc ttccattaaa gttgcccgag cccctctcag aatgttttgt 6800

 attagtagga gtactgaaat acatctttcc ttccttaaca caccttgtgc 6850

 atattgcatt ttccaaaata aacaagttta atggtttc 6888

<210> 648
<211> 499
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4245-4279
<223> Unknown amino acid

<400> 648
 Met Ser Ser Arg Arg Gln Ala His Gly Val Gly Glu Pro Arg Ser
   1               5                  10                  15

 Ala Ala Ala Cys Gly Gly Gly Ser Gly Gly Glu Ala Gly Arg Leu
                  20                  25                  30

 Phe Pro Gly Lys Glu Ala Arg Ala Ser Glu Arg Gly Arg Ala Arg
                  35                  40                  45

 Arg Pro Ser Leu Thr Arg Pro Pro Ser Gln Arg Pro Pro Pro Ala
                  50                  55                  60

 Pro Ala Ser Leu Leu Pro Ser Ala Gln Thr Ile Arg Ser His Arg
                  65                  70                  75

 Ala Pro Arg Pro Thr Trp Trp Pro Arg Pro Trp Pro Pro Pro Pro
                  80                  85                  90

 Arg Arg Phe Pro Glu Leu Val Pro Asp Ala Arg Pro Gly Gly Gly
                  95                 100                 105

 Gly Ser Ala Ala Thr Ala Ala Ser Gly Glu Arg Gly Arg Glu Gly
                 110                 115                 120

 Val Cys Ala Arg Cys Glu Gln Gly Val Pro Ala Gly Leu Gln Arg
                 125                 130                 135

 Arg His Phe Gly Arg Met Thr Leu Glu Ser Ile Met Ala Cys Cys
                 140                 145                 150

 Leu Ser Glu Glu Ala Lys Glu Ala Arg Arg Ile Asn Asp Glu Ile
                 155                 160                 165

 Glu Arg Gln Leu Arg Arg Asp Lys Arg Asp Ala Arg Arg Glu Leu
                 170                 175                 180

 Lys Leu Leu Leu Leu Gly Thr Gly Glu Ser Gly Lys Ser Thr Phe
                 185                 190                 195

 Ile Lys Gln Met Arg Ile Ile His Gly Ser Gly Tyr Ser Asp Glu
                 200                 205                 210

 Asp Lys Arg Gly Phe Thr Lys Leu Val Tyr Gln Asn Ile Phe Thr
                 215                 220                 225

 Ala Met Gln Ala Met Ile Arg Ala Met Asp Thr Leu Lys Ile Pro
                 230                 235                 240

 Tyr Lys Tyr Glu His Asn Lys Ala His Ala Gln Leu Val Arg Glu
                 245                 250                 255

 Val Asp Val Glu Lys Val Ser Ala Phe Glu Asn Pro Tyr Val Asp
                 260                 265                 270

 Ala Ile Lys Ser Leu Trp Asn Asp Pro Gly Ile Gln Glu Cys Tyr
                 275                 280                 285

 Asp Arg Arg Arg Glu Tyr Gln Leu Ser Asp Ser Thr Lys Tyr Tyr
                 290                 295                 300

 Leu Asn Asp Leu Asp Arg Val Ala Asp Pro Ala Tyr Leu Pro Thr
                 305                 310                 315

 Gln Gln Asp Val Leu Arg Val Arg Val Pro Thr Thr Gly Ile Ile
                 320                 325                 330

 Glu Tyr Pro Phe Asp Leu Gln Ser Val Ile Phe Arg Met Val Asp
                 335                 340                 345

 Val Gly Gly Gln Arg Ser Glu Arg Arg Lys Trp Ile His Cys Phe
                 350                 355                 360

 Glu Asn Val Thr Ser Ile Met Phe Leu Val Ala Leu Ser Glu Tyr
                 365                 370                 375

 Asp Gln Val Leu Val Glu Ser Asp Asn Glu Asn Arg Met Glu Glu
                 380                 385                 390

 Ser Lys Ala Leu Phe Arg Thr Ile Ile Thr Tyr Pro Trp Phe Gln
                 395                 400                 405

 Asn Ser Ser Val Ile Leu Phe Leu Asn Lys Lys Asp Leu Leu Glu
                 410                 415                 420

 Glu Lys Ile Met Tyr Ser His Leu Val Asp Tyr Phe Pro Glu Tyr
                 425                 430                 435

 Asp Gly Pro Gln Arg Asp Ala Gln Ala Ala Arg Glu Phe Ile Leu
                 440                 445                 450

 Lys Met Phe Val Asp Leu Asn Pro Asp Ser Asp Lys Ile Ile Tyr
                 455                 460                 465

 Ser His Phe Thr Cys Ala Thr Asp Thr Glu Asn Ile Arg Phe Val
                 470                 475                 480

 Phe Ala Ala Val Lys Asp Thr Ile Leu Gln Leu Asn Leu Lys Glu
                 485                 490                 495

 Tyr Asn Leu Val


<210> 649
<211> 7222
<212> DNA
<213> Homo sapien

<400> 649
 agccggacgg cgcggtggtc gggacagact ggccgttgct gtggagacgc 50

 ctggagagtt gtggactggg gcaacctttg ccagtgatga gaagtgatgc 100

 tcgtggcagt gctgaatctc tctgaatatg attcgaattg cagccttaaa 150

 tgccagctcc accattgagg atgatcatga aggaagcttt aaaagtcaca 200

 aaacccagac aaaggaggct caggaagcag aggcttttgc attgtaccac 250

 aaggcccttg atctgcagaa acatgaccgg tttgaggagt ctgccaaagc 300

 ctaccatgag ctcttggagg cgagcctgct gcgggaggca gtttcatccg 350

 gtgatgagaa agaggggttg aaacaccctg ggctgatact gaaatattcc 400

 acttataaga acttggccca gctggcagcc cagcgggagg atctggagac 450

 agccatggag ttctacttag aggcagtgat gctggactcc acagatgtca 500

 acctctggta taagattgga catgtggccc tgaggctcat ccggatcccc 550

 ctggctcgcc atgcttttga ggaagggctg cggtgcaatc ctgaccactg 600

 gccctgtttg gataacctaa tcactgtcct gtacaccctc agtgattaca 650

 caacatgtct gtacttcatc tgcaaagctt tggagaagga ttgccggtac 700

 agcaaagggc tggtcctcaa ggagaagatt tttgaggagc agccttgtct 750

 ccggaaggac tctctcagaa tgttcctcaa atgtgacatg tcgattcacg 800

 atgtttcggt gagtgcagct gagacacagg cgattgtaga tgaggccttg 850

 gggctgcgaa aaaagaggca agcgctgatt gtgcgggaga aggagccgga 900

 cctgaaactt gtgcagccca ttcctttctt cacctggaag tgcctcggag 950

 agagcttgct ggccatgtac aatcatctca ccacctgtga gcccccacgt 1000

 cccagccttg gcaaaaggat tgatttgtcg gactaccagg accccagcca 1050

 gcctcttgag tcctccatgg tggtgacgcc agttaacgtg atccagccaa 1100

 gcactgtcag caccaaccca gctgtggctg tcgccgagcc tgtggtctcc 1150

 tacacctctg tggctacaac cagcttccca ctgcacagtc ctggtctgtt 1200

 ggagacaggc gctcctgtgg gtgatatttc tgggggagat aaatccaaga 1250

 aaggggtaaa acggaagaag atttcagaag agagtggaga aacagcaaag 1300

 cggcggtctg cccgtgtccg aaacaccaag tgcaaaaaag aagagaaagt 1350

 agacttccag gagcttctga tgaagttctt gccgtccagg ttaagaaagc 1400

 tggaccctga ggaggaagat gattccttta ataactatga agtccagtca 1450

 gaagccaaac tggaaagctt cccaagcatt gggcctcaaa ggctgtcatt 1500

 tgactcagcc acattcatgg aatctgaaaa gcaggacgtg catgagttcc 1550

 tgctggagaa cctaaccaac gggggcatcc tggagctgat gatgcgctac 1600

 ctgaaagcca tgggccacaa gttcttggta aggtggcctc caggcttggc 1650

 ggaggtcgtg ctcagcgtct accacagctg gaggaggcac agcaccagcc 1700

 tgcccaaccc gctgctgagg gactgcagca acaagcacat caaggacatg 1750

 atgctgatgt ctctctcctg catggaactc cagctggacc agtggctgct 1800

 gaccaaaggc agaagctctg cagtgtctcc tcggaactgt cctgctggta 1850

 tggtgaatgg cagatttgga cctgacttcc cagggaccca ctgcctgggt 1900

 gacctcctac agctgtcatt tgcctcgtcc cagcgcgacc tgttcgagga 1950

 tggttggctg gagtttgtgg tccgtgttta ctggctgaag gctcgcttcc 2000

 tggcgctgca gggagacatg gagcaggccc tggagaacta tgacatctgc 2050

 acagaaatgc tccagagttc caccgccatc caggtggagg caggggctga 2100

 acgaagagac attgtcatcc ggctgcccaa cctccataat gactctgtgg 2150

 tttccctgga ggagattgat aagaacctga agtcgctgga gcggtgccag 2200

 tccctggagg agattcagcg gctgtatgaa gcaggcgact acaaggctgt 2250

 tgtgcatctg ctccgcccca ctttgtgcac cagtgggttt gaccgggcca 2300

 aacacctgga gtttatgact tccattcctg agaggccagc ccagctgctt 2350

 cttctgcagg actccttgct ccggctgaag gactatcggc agtgttttga 2400

 gtgttccgat gtggctctga acgaggctgt ccagcagatg gtgaactcag 2450

 gtgaggctgc cgccaaggag gagtgggtgg ccacagtgac ccaactgctg 2500

 atgggcatcg agcaggccct ctctgcggac agcagtggta gcatcctgaa 2550

 ggtatcatcc tccaccactg gccttgtgcg gctcaccaac aacctcatcc 2600

 aggtcattga ctgcagcatg gctgtgcagg aggaggccaa ggagccccac 2650

 gtctcttcag tgctaccctg gatcattcta caccggatca tctggcagga 2700

 ggaagacacc ttccattctc tgtgccacca gcagcagctc caaaacccag 2750

 cggaggaagg gatgtcagag acgcccatgc tcccatcctc cctcatgctg 2800

 ctgaacacag cccacgagta tttgggcaga aggtcctggt gctgcaattc 2850

 agatggggct ctgctgcgat tctatgtgcg agtactccag aaggaactgg 2900

 ctgcatccac ctctgaagac acgcaccctt acaaggagga gctggagaca 2950

 gccttggagc agtgcttcta ctgcctgtac agcttcccca gcaagaagag 3000

 taaggccagg tacctggagg aacactcggc ccagcaggtg gatcttatat 3050

 gggaggatgc actgttcatg tttgagtatt ttaagcccaa gacccttcct 3100

 gaatttgaca gctataagac cagcaccgtg tctgctgact tggccaacct 3150

 actgaagaga attgccacca ttgtgcctcg cacagagagg ccagccctta 3200

 gcctggacaa agtctctgcc tacattgagg gaacttcaac tgaggtaccc 3250

 tgcctcccag agggggctga cccctcccct ccagtggtga acgagcttta 3300

 ctacctcctg gctgattatc atttcaaaaa caaggagcag tccaaggcca 3350

 tcaagttcta catgcatgac atctgcatct gccccaatag gtttgattcc 3400

 tgggcaggca tggctctggc ccgggccagc cgcattcagg acaagctgaa 3450

 ctccaatgag ctgaagagtg atgggcccat ttggaagcat gccacgcccg 3500

 tcttgaactg cttccgtcgg gccctggaga ttgacagctc caacttgtcc 3550

 ctatggattg agtatggcac catgtcctat gccttgcact cattcgcctc 3600

 acgtcaattg aagcagtgga gaggcgagct gccccctgag ctcgtgcagc 3650

 agatggaggg ccggcgcgac agcatgctag agacagccaa gcactgtttc 3700

 acatcagcag cccgctgcga gggtgatggt gacgaggagg agtggctcat 3750

 ccactacatg ctgggcaagg tggctgagaa gcagcagcag ccacccaccg 3800

 tttacttgct gcactacagg caggctggcc actacctgca cgaggaggct 3850

 gcccgctacc ccaagaagat ccactaccac aacccacctg agctggccat 3900

 ggaggccctg gaggtgtact ttcggctcca tgcttccatc ctgaagctcc 3950

 tggggaagcc cgattctggg gttggtgcag aggtcctggt caactttatg 4000

 aaggaggctg cagaaggacc ctttgccagg ggcgaggaga agaacacacc 4050

 caaagcttca gaaaaggaga aggcctgcct ggtggacgag gactcccact 4100

 cttcagctgg gacactgccg ggccccggag cctccctccc ctcctcctct 4150

 ggcccaggtc tgacatcccc accttacaca gccactccga ttgaccacga 4200

 ttacgtcaaa tgtaaaaaac cccaccagca ggcaacgccg gacgaccgaa 4250

 gccaggacag cacagccgta gcactctcag actctagctc aacgcaggac 4300

 ttctttaatg agcccaccag cttactggaa ggctccagga aatcctacac 4350

 agagaagagg ctgcccattc tcagttccca agcaggagcg acgggtaaag 4400

 atcttcaggg ggccacagaa gaaagaggaa aaaacgagga gtcattggag 4450

 agtacagaag gcttccgggc tgcagagcaa ggtgtccaga agcctgctgc 4500

 agaaacccca gcctctgctt gcatccctgg caagccctca gcatccacac 4550

 ccaccctgtg ggatgggaag aagagagggg acctcccagg ggagccagtg 4600

 gccttccccc aggggctgcc ggctggtgct gaggagcagc ggcagtttct 4650

 cacagagcag tgcatcgcct ccttccgcct gtgcctgagc cgcttccccc 4700

 agcactataa gagtctctac cgtctggcct tcctctacac ctacagcaag 4750

 acccaccgga acctccagtg ggcccgcgac gtgttgctag gcagcagtat 4800

 cccgtggcaa caactgcagc acatgccggc acaggggctc ttctgcgaga 4850

 ggaacaagac caatttcttc aacggcatct ggcggatccc cgtggacgag 4900

 attgaccggc cgggcagctt tgcctggcac atgaaccgct ccatcgtgct 4950

 gctgctcaag gtgctggccc agctgcggga ccacagcacc ctgctgaagg 5000

 tgtcctccat gcttcagcgg accccagacc agggcaagaa gtatctgcga 5050

 gatgctgacc gccaggtcct ggcgcagcgg gccttcatcc tcactgtgaa 5100

 ggtgctcgaa gacacgctga gcgagctcgc agaggggtca gaacgcccag 5150

 ggcccaaggt ctgtggcctc cccggagcca ggatgaccac cgatgtctca 5200

 cacaaggcca gtcctgagga tggccaggag ggcctccccc agccgaagaa 5250

 gccccctctg gctgatggct cagggccagg gcccgagcca ggaggcaaag 5300

 tgggcctcct caaccaccgg cctgtggcca tggatgcagg agacagtgca 5350

 gaccaaagcg gggagcggaa ggataaagag agcccacggg cagggcccac 5400

 tgagcccatg gacacgagtg aggccactgt ttgccactca gacttggagc 5450

 ggacaccacc cctgctgcca ggtcgccccg caagggaccg gggccccgag 5500

 agccggccca ctgagctgtc cctggaggag ctgagcatca gtgcccggca 5550

 gcagcccacc ccgctcaccc cagcccagcc agcccccgcc cccgcccccg 5600

 ccaccaccac agggaccagg gcagggggcc acccggagga gccgctctcc 5650

 cggctcagcc gcaagaggaa gctcctggag gacacagagt caggcaagac 5700

 acttctgttg gatgcctacc gtgtgtggca gcagggccag aagggtgtgg 5750

 cctatgacct gggccgtgtg gagaggatca tgtcggagac ctacatgctc 5800

 atcaagcagg tggatgagga ggctgcgctg gagcaggctg tgaagttctg 5850

 ccaggtccat cttggggctg ccgcccagag acaggcctcg ggggacaccc 5900

 ccaccactcc aaagcacccc aaagacagcc gagagaactt ctttcctgtg 5950

 acagtggtgc ccacagcccc tgaccctgtg ccagctgact ctgtccagcg 6000

 gcccagtgat gctcacacca agcctcgccc tgcactagct gccgccacaa 6050

 ctattatcac ctgccctccg tcagcatcag cttccaccct ggaccagtcc 6100

 aaggaccctg ggcctccccg gccacacagg cctgaagcta cccccagcat 6150

 ggcctctctg ggcccagagg gagaagagct ggcgagagtg gcagagggca 6200

 ccagcttccc gcctcaggag ccacggcaca gtccgcaggt gaagatggcc 6250

 cccacaagtt ccccggcaga gccacactgc tggccggcag aggctgccct 6300

 gggcacaggc gctgagccca cctgcagcca ggaggggaaa ctgaggcctg 6350

 agccgagaag ggatggggag gctcaggagg ctgcgagtga gactcagccc 6400

 ctgagctctc ccccaacagc tgccagctcc aaggccccca gcagtgggag 6450

 tgcccagcca ccagagggtc acccaggcaa gcctgagccc agccgggcta 6500

 agtcccgccc cctgcccaac atgccaaagc tggtcatccc ctccgccgcc 6550

 accaagttcc cccctgagat caccgtcacg ccacccaccc caaccctgct 6600

 ctcccccaaa ggcagcatct cggaggagac caagcagaag ctgaagtcag 6650

 ccatcctttc tgcccagtct gctgccaacg tgaggaagga gagcctatgc 6700

 cagccagccc tggaggtcct ggagacatcc agccaggagt cctcgctgga 6750

 gagcgagaca gacgaggacg acgactacat ggacatttga ggggccactg 6800

 cagccccacc gccacgcccc aggggaccag ccaggcctgg aatgccccct 6850

 gggcaggacc ctgggcagga ccagaggccc acatggatgc cactccccac 6900

 acagccccca ggcctgccca gcccacctcc tcatggcatc ctccctgtac 6950

 ccaggtcagg ctgtccacac cacatgggag cccagaggag gaggggcccg 7000

 ccttagccat gtgaaggtgg attggtcgcc atctgcacgc caggcggcat 7050

 ccttttctat gaagtgttga ctttgtaaat ctgcccacac ccagctggcc 7100

 atatccaccc ctcgacgccg ggatgagccg gctctgcctg tgtcacagtg 7150

 gaggggtcct ttagggccag gctcacccct cacccttttt ttggttgctt 7200

 ttctaataaa gatggaacag tt 7222

<210> 650
<211> 2000
<212> PRT
<213> Homo sapien

<400> 650
 Met Ile Arg Ile Ala Ala Leu Asn Ala Ser Ser Thr Ile Glu Asp
   1               5                  10                  15

 Asp His Glu Gly Ser Phe Lys Ser His Lys Thr Gln Thr Lys Glu
                  20                  25                  30

 Ala Gln Glu Ala Glu Ala Phe Ala Leu Tyr His Lys Ala Leu Asp
                  35                  40                  45

 Leu Gln Lys His Asp Arg Phe Glu Glu Ser Ala Lys Ala Tyr His
                  50                  55                  60

 Glu Leu Leu Glu Ala Ser Leu Leu Arg Glu Ala Val Ser Ser Gly
                  65                  70                  75

 Asp Glu Lys Glu Gly Leu Lys His Pro Gly Leu Ile Leu Lys Tyr
                  80                  85                  90

 Ser Thr Tyr Lys Asn Leu Ala Gln Leu Ala Ala Gln Arg Glu Asp
                  95                 100                 105

 Leu Glu Thr Ala Met Glu Phe Tyr Leu Glu Ala Val Met Leu Asp
                 110                 115                 120

 Ser Thr Asp Val Asn Leu Trp Tyr Lys Ile Gly His Val Ala Leu
                 125                 130                 135

 Arg Leu Ile Arg Ile Pro Leu Ala Arg His Ala Phe Glu Glu Gly
                 140                 145                 150

 Leu Arg Cys Asn Pro Asp His Trp Pro Cys Leu Asp Asn Leu Ile
                 155                 160                 165

 Thr Val Leu Tyr Thr Leu Ser Asp Tyr Thr Thr Cys Leu Tyr Phe
                 170                 175                 180

 Ile Cys Lys Ala Leu Glu Lys Asp Cys Arg Tyr Ser Lys Gly Leu
                 185                 190                 195

 Val Leu Lys Glu Lys Ile Phe Glu Glu Gln Pro Cys Leu Arg Lys
                 200                 205                 210

 Asp Ser Leu Arg Met Phe Leu Lys Cys Asp Met Ser Ile His Asp
                 215                 220                 225

 Val Ser Val Ser Ala Ala Glu Thr Gln Ala Ile Val Asp Glu Ala
                 230                 235                 240

 Leu Gly Leu Arg Lys Lys Arg Gln Ala Leu Ile Val Arg Glu Lys
                 245                 250                 255

 Glu Pro Asp Leu Lys Leu Val Gln Pro Ile Pro Phe Phe Thr Trp
                 260                 265                 270

 Lys Cys Leu Gly Glu Ser Leu Leu Ala Met Tyr Asn His Leu Thr
                 275                 280                 285

 Thr Cys Glu Pro Pro Arg Pro Ser Leu Gly Lys Arg Ile Asp Leu
                 290                 295                 300

 Ser Asp Tyr Gln Asp Pro Ser Gln Pro Leu Glu Ser Ser Met Val
                 305                 310                 315

 Val Thr Pro Val Asn Val Ile Gln Pro Ser Thr Val Ser Thr Asn
                 320                 325                 330

 Pro Ala Val Ala Val Ala Glu Pro Val Val Ser Tyr Thr Ser Val
                 335                 340                 345

 Ala Thr Thr Ser Phe Pro Leu His Ser Pro Gly Leu Leu Glu Thr
                 350                 355                 360

 Gly Ala Pro Val Gly Asp Ile Ser Gly Gly Asp Lys Ser Lys Lys
                 365                 370                 375

 Gly Val Lys Arg Lys Lys Ile Ser Glu Glu Ser Gly Glu Thr Ala
                 380                 385                 390

 Lys Arg Arg Ser Ala Arg Val Arg Asn Thr Lys Cys Lys Lys Glu
                 395                 400                 405

 Glu Lys Val Asp Phe Gln Glu Leu Leu Met Lys Phe Leu Pro Ser
                 410                 415                 420

 Arg Leu Arg Lys Leu Asp Pro Glu Glu Glu Asp Asp Ser Phe Asn
                 425                 430                 435

 Asn Tyr Glu Val Gln Ser Glu Ala Lys Leu Glu Ser Phe Pro Ser
                 440                 445                 450

 Ile Gly Pro Gln Arg Leu Ser Phe Asp Ser Ala Thr Phe Met Glu
                 455                 460                 465

 Ser Glu Lys Gln Asp Val His Glu Phe Leu Leu Glu Asn Leu Thr
                 470                 475                 480

 Asn Gly Gly Ile Leu Glu Leu Met Met Arg Tyr Leu Lys Ala Met
                 485                 490                 495

 Gly His Lys Phe Leu Val Arg Trp Pro Pro Gly Leu Ala Glu Val
                 500                 505                 510

 Val Leu Ser Val Tyr His Ser Trp Arg Arg His Ser Thr Ser Leu
                 515                 520                 525

 Pro Asn Pro Leu Leu Arg Asp Cys Ser Asn Lys His Ile Lys Asp
                 530                 535                 540

 Met Met Leu Met Ser Leu Ser Cys Met Glu Leu Gln Leu Asp Gln
                 545                 550                 555

 Trp Leu Leu Thr Lys Gly Arg Ser Ser Ala Val Ser Pro Arg Asn
                 560                 565                 570

 Cys Pro Ala Gly Met Val Asn Gly Arg Phe Gly Pro Asp Phe Pro
                 575                 580                 585

 Gly Thr His Cys Leu Gly Asp Leu Leu Gln Leu Ser Phe Ala Ser
                 590                 595                 600

 Ser Gln Arg Asp Leu Phe Glu Asp Gly Trp Leu Glu Phe Val Val
                 605                 610                 615

 Arg Val Tyr Trp Leu Lys Ala Arg Phe Leu Ala Leu Gln Gly Asp
                 620                 625                 630

 Met Glu Gln Ala Leu Glu Asn Tyr Asp Ile Cys Thr Glu Met Leu
                 635                 640                 645

 Gln Ser Ser Thr Ala Ile Gln Val Glu Ala Gly Ala Glu Arg Arg
                 650                 655                 660

 Asp Ile Val Ile Arg Leu Pro Asn Leu His Asn Asp Ser Val Val
                 665                 670                 675

 Ser Leu Glu Glu Ile Asp Lys Asn Leu Lys Ser Leu Glu Arg Cys
                 680                 685                 690

 Gln Ser Leu Glu Glu Ile Gln Arg Leu Tyr Glu Ala Gly Asp Tyr
                 695                 700                 705

 Lys Ala Val Val His Leu Leu Arg Pro Thr Leu Cys Thr Ser Gly
                 710                 715                 720

 Phe Asp Arg Ala Lys His Leu Glu Phe Met Thr Ser Ile Pro Glu
                 725                 730                 735

 Arg Pro Ala Gln Leu Leu Leu Leu Gln Asp Ser Leu Leu Arg Leu
                 740                 745                 750

 Lys Asp Tyr Arg Gln Cys Phe Glu Cys Ser Asp Val Ala Leu Asn
                 755                 760                 765

 Glu Ala Val Gln Gln Met Val Asn Ser Gly Glu Ala Ala Ala Lys
                 770                 775                 780

 Glu Glu Trp Val Ala Thr Val Thr Gln Leu Leu Met Gly Ile Glu
                 785                 790                 795

 Gln Ala Leu Ser Ala Asp Ser Ser Gly Ser Ile Leu Lys Val Ser
                 800                 805                 810

 Ser Ser Thr Thr Gly Leu Val Arg Leu Thr Asn Asn Leu Ile Gln
                 815                 820                 825

 Val Ile Asp Cys Ser Met Ala Val Gln Glu Glu Ala Lys Glu Pro
                 830                 835                 840

 His Val Ser Ser Val Leu Pro Trp Ile Ile Leu His Arg Ile Ile
                 845                 850                 855

 Trp Gln Glu Glu Asp Thr Phe His Ser Leu Cys His Gln Gln Gln
                 860                 865                 870

 Leu Gln Asn Pro Ala Glu Glu Gly Met Ser Glu Thr Pro Met Leu
                 875                 880                 885

 Pro Ser Ser Leu Met Leu Leu Asn Thr Ala His Glu Tyr Leu Gly
                 890                 895                 900

 Arg Arg Ser Trp Cys Cys Asn Ser Asp Gly Ala Leu Leu Arg Phe
                 905                 910                 915

 Tyr Val Arg Val Leu Gln Lys Glu Leu Ala Ala Ser Thr Ser Glu
                 920                 925                 930

 Asp Thr His Pro Tyr Lys Glu Glu Leu Glu Thr Ala Leu Glu Gln
                 935                 940                 945

 Cys Phe Tyr Cys Leu Tyr Ser Phe Pro Ser Lys Lys Ser Lys Ala
                 950                 955                 960

 Arg Tyr Leu Glu Glu His Ser Ala Gln Gln Val Asp Leu Ile Trp
                 965                 970                 975

 Glu Asp Ala Leu Phe Met Phe Glu Tyr Phe Lys Pro Lys Thr Leu
                 980                 985                 990

 Pro Glu Phe Asp Ser Tyr Lys Thr Ser Thr Val Ser Ala Asp Leu
                 995                1000                1005

 Ala Asn Leu Leu Lys Arg Ile Ala Thr Ile Val Pro Arg Thr Glu
                1010                1015                1020

 Arg Pro Ala Leu Ser Leu Asp Lys Val Ser Ala Tyr Ile Glu Gly
                1025                1030                1035

 Thr Ser Thr Glu Val Pro Cys Leu Pro Glu Gly Ala Asp Pro Ser
                1040                1045                1050

 Pro Pro Val Val Asn Glu Leu Tyr Tyr Leu Leu Ala Asp Tyr His
                1055                1060                1065

 Phe Lys Asn Lys Glu Gln Ser Lys Ala Ile Lys Phe Tyr Met His
                1070                1075                1080

 Asp Ile Cys Ile Cys Pro Asn Arg Phe Asp Ser Trp Ala Gly Met
                1085                1090                1095

 Ala Leu Ala Arg Ala Ser Arg Ile Gln Asp Lys Leu Asn Ser Asn
                1100                1105                1110

 Glu Leu Lys Ser Asp Gly Pro Ile Trp Lys His Ala Thr Pro Val
                1115                1120                1125

 Leu Asn Cys Phe Arg Arg Ala Leu Glu Ile Asp Ser Ser Asn Leu
                1130                1135                1140

 Ser Leu Trp Ile Glu Tyr Gly Thr Met Ser Tyr Ala Leu His Ser
                1145                1150                1155

 Phe Ala Ser Arg Gln Leu Lys Gln Trp Arg Gly Glu Leu Pro Pro
                1160                1165                1170

 Glu Leu Val Gln Gln Met Glu Gly Arg Arg Asp Ser Met Leu Glu
                1175                1180                1185

 Thr Ala Lys His Cys Phe Thr Ser Ala Ala Arg Cys Glu Gly Asp
                1190                1195                1200

 Gly Asp Glu Glu Glu Trp Leu Ile His Tyr Met Leu Gly Lys Val
                1205                1210                1215

 Ala Glu Lys Gln Gln Gln Pro Pro Thr Val Tyr Leu Leu His Tyr
                1220                1225                1230

 Arg Gln Ala Gly His Tyr Leu His Glu Glu Ala Ala Arg Tyr Pro
                1235                1240                1245

 Lys Lys Ile His Tyr His Asn Pro Pro Glu Leu Ala Met Glu Ala
                1250                1255                1260

 Leu Glu Val Tyr Phe Arg Leu His Ala Ser Ile Leu Lys Leu Leu
                1265                1270                1275

 Gly Lys Pro Asp Ser Gly Val Gly Ala Glu Val Leu Val Asn Phe
                1280                1285                1290

 Met Lys Glu Ala Ala Glu Gly Pro Phe Ala Arg Gly Glu Glu Lys
                1295                1300                1305

 Asn Thr Pro Lys Ala Ser Glu Lys Glu Lys Ala Cys Leu Val Asp
                1310                1315                1320

 Glu Asp Ser His Ser Ser Ala Gly Thr Leu Pro Gly Pro Gly Ala
                1325                1330                1335

 Ser Leu Pro Ser Ser Ser Gly Pro Gly Leu Thr Ser Pro Pro Tyr
                1340                1345                1350

 Thr Ala Thr Pro Ile Asp His Asp Tyr Val Lys Cys Lys Lys Pro
                1355                1360                1365

 His Gln Gln Ala Thr Pro Asp Asp Arg Ser Gln Asp Ser Thr Ala
                1370                1375                1380

 Val Ala Leu Ser Asp Ser Ser Ser Thr Gln Asp Phe Phe Asn Glu
                1385                1390                1395

 Pro Thr Ser Leu Leu Glu Gly Ser Arg Lys Ser Tyr Thr Glu Lys
                1400                1405                1410

 Arg Leu Pro Ile Leu Ser Ser Gln Ala Gly Ala Thr Gly Lys Asp
                1415                1420                1425

 Leu Gln Gly Ala Thr Glu Glu Arg Gly Lys Asn Glu Glu Ser Leu
                1430                1435                1440

 Glu Ser Thr Glu Gly Phe Arg Ala Ala Glu Gln Gly Val Gln Lys
                1445                1450                1455

 Pro Ala Ala Glu Thr Pro Ala Ser Ala Cys Ile Pro Gly Lys Pro
                1460                1465                1470

 Ser Ala Ser Thr Pro Thr Leu Trp Asp Gly Lys Lys Arg Gly Asp
                1475                1480                1485

 Leu Pro Gly Glu Pro Val Ala Phe Pro Gln Gly Leu Pro Ala Gly
                1490                1495                1500

 Ala Glu Glu Gln Arg Gln Phe Leu Thr Glu Gln Cys Ile Ala Ser
                1505                1510                1515

 Phe Arg Leu Cys Leu Ser Arg Phe Pro Gln His Tyr Lys Ser Leu
                1520                1525                1530

 Tyr Arg Leu Ala Phe Leu Tyr Thr Tyr Ser Lys Thr His Arg Asn
                1535                1540                1545

 Leu Gln Trp Ala Arg Asp Val Leu Leu Gly Ser Ser Ile Pro Trp
                1550                1555                1560

 Gln Gln Leu Gln His Met Pro Ala Gln Gly Leu Phe Cys Glu Arg
                1565                1570                1575

 Asn Lys Thr Asn Phe Phe Asn Gly Ile Trp Arg Ile Pro Val Asp
                1580                1585                1590

 Glu Ile Asp Arg Pro Gly Ser Phe Ala Trp His Met Asn Arg Ser
                1595                1600                1605

 Ile Val Leu Leu Leu Lys Val Leu Ala Gln Leu Arg Asp His Ser
                1610                1615                1620

 Thr Leu Leu Lys Val Ser Ser Met Leu Gln Arg Thr Pro Asp Gln
                1625                1630                1635

 Gly Lys Lys Tyr Leu Arg Asp Ala Asp Arg Gln Val Leu Ala Gln
                1640                1645                1650

 Arg Ala Phe Ile Leu Thr Val Lys Val Leu Glu Asp Thr Leu Ser
                1655                1660                1665

 Glu Leu Ala Glu Gly Ser Glu Arg Pro Gly Pro Lys Val Cys Gly
                1670                1675                1680

 Leu Pro Gly Ala Arg Met Thr Thr Asp Val Ser His Lys Ala Ser
                1685                1690                1695

 Pro Glu Asp Gly Gln Glu Gly Leu Pro Gln Pro Lys Lys Pro Pro
                1700                1705                1710

 Leu Ala Asp Gly Ser Gly Pro Gly Pro Glu Pro Gly Gly Lys Val
                1715                1720                1725

 Gly Leu Leu Asn His Arg Pro Val Ala Met Asp Ala Gly Asp Ser
                1730                1735                1740

 Ala Asp Gln Ser Gly Glu Arg Lys Asp Lys Glu Ser Pro Arg Ala
                1745                1750                1755

 Gly Pro Thr Glu Pro Met Asp Thr Ser Glu Ala Thr Val Cys His
                1760                1765                1770

 Ser Asp Leu Glu Arg Thr Pro Pro Leu Leu Pro Gly Arg Pro Ala
                1775                1780                1785

 Arg Asp Arg Gly Pro Glu Ser Arg Pro Thr Glu Leu Ser Leu Glu
                1790                1795                1800

 Glu Leu Ser Ile Ser Ala Arg Gln Gln Pro Thr Pro Leu Thr Pro
                1805                1810                1815

 Ala Gln Pro Ala Pro Ala Pro Ala Pro Ala Thr Thr Thr Gly Thr
                1820                1825                1830

 Arg Ala Gly Gly His Pro Glu Glu Pro Leu Ser Arg Leu Ser Arg
                1835                1840                1845

 Lys Arg Lys Leu Leu Glu Asp Thr Glu Ser Gly Lys Thr Leu Leu
                1850                1855                1860

 Leu Asp Ala Tyr Arg Val Trp Gln Gln Gly Gln Lys Gly Val Ala
                1865                1870                1875

 Tyr Asp Leu Gly Arg Val Glu Arg Ile Met Ser Glu Thr Tyr Met
                1880                1885                1890

 Leu Ile Lys Gln Val Asp Glu Glu Ala Ala Leu Glu Gln Ala Val
                1895                1900                1905

 Lys Phe Cys Gln Val His Leu Gly Ala Ala Ala Gln Arg Gln Ala
                1910                1915                1920

 Ser Gly Asp Thr Pro Thr Thr Pro Lys His Pro Lys Asp Ser Arg
                1925                1930                1935

 Glu Asn Phe Phe Pro Val Thr Val Val Pro Thr Ala Pro Asp Pro
                1940                1945                1950

 Val Pro Ala Asp Ser Val Gln Arg Pro Ser Asp Ala His Thr Lys
                1955                1960                1965

 Pro Arg Pro Ala Leu Ala Ala Ala Thr Thr Ile Ile Thr Cys Pro
                1970                1975                1980

 Pro Ser Ala Ser Ala Ser Thr Leu Asp Gln Ser Lys Asp Pro Gly
                1985                1990                1995

 Pro Pro Arg Pro His
                2000

<210> 651
<211> 4765
<212> DNA
<213> Homo sapien

<400> 651
 aggccctctg taaatgtttg ctattaatgc aatgctgaga tcccagtgaa 50

 cagaatctgg cttagaagaa gtggatatcc acggtgcccg agcctaatct 100

 tacatcttgg atttgtaagt ggcatttatt gagttagaac atgagcttga 150

 gcacgcggtc acacattgtt tcagcaaaca ctggttaggc accagatgct 200

 acgtgcaagc actgccctac atgctgggac gcaactgtag taggaatgaa 250

 ataacgccag cattcctgca tgcgggcagt gcgggccctg tacagaaagg 300

 tacacgagat aggcatcctc acatccattg tcctgggagg aaactgaggc 350

 tttgagaaac ggagaacttg ccgggccatt tgactctacg tcatcccctc 400

 ccccatcaat gccctgaaca gcctcctgta cacccttaag gaacttactt 450

 tgtaatgatt attaagaact cagcgagacc ccgagcatca cctcggcata 500

 tcgcatcctt tctctagaga acccctaatg ttggaaggga tcagagcgca 550

 cctcctccgc tcctgggagc acccccttca ctaataatac cttggggatg 600

 ggtcggaagg aaaggaaagg agacgcgaga ggtgtagtca gatgtgcctg 650

 cgaagcccag gctcctccgg agatccttcc gtccgtccct acaggagaag 700

 gctggcccgg gctgctccac tccccggagc tgcagactga gtcgccaggt 750

 ttctgtgcct tcaaagccct gcgcgacggc cacaccaaac acccaaacct 800

 tgggcaggga ccaaacggtc acttccccgc cctccgggct caatatgcaa 850

 atccgagcac caggaagtag ctgggacctc tcggccgagc ccagagacag 900

 ccagttcctc tcccgccgcg ccgggccgcg ctgccgctcg ctccccggcc 950

 gtggcgcctc cgggccagac gcgctgcagc ctccagcccg cggcaagcgg 1000

 gcggggcggc cgcgccaccc ccggccccgc gccagcagcc cctcgccgcg 1050

 cgtccagcgt tcccggccag cagcctcccc atacgcaggt cctgctgggc 1100

 cgccccgtcg cgccccccac tctgaactca agtcaccgtg gagctccgcc 1150

 gccccgaaac tttcaccgcg agcgggaaat atgggatgta taaaatcaaa 1200

 agggaaagac agcttgagtg acgatggagt agatttgaag actcaaccag 1250

 tacgtaatac tgaaagaact atttatgtga gagatccaac gtccaataaa 1300

 cagcaaaggc cagttccaga atctcagctt ttacctggac agaggtttca 1350

 aactaaagat ccagaggaac aaggagacat tgtggtagcc ttgtacccct 1400

 atgatggcat ccacccggac gacttgtctt tcaagaaagg agagaagatg 1450

 aaagtcctgg aggagcatgg agaatggtgg aaagcaaagt cccttttaac 1500

 aaaaaaagaa ggcttcatcc ccagcaacta tgtggccaaa ctcaacacct 1550

 tagaaacaga agagtggttt ttcaaggata taaccgggaa ggacgcagaa 1600

 aggcagcttt tggcaccagg aaatagcgct ggagctttcc ttattagaga 1650

 aagtgaaaca ttaaaaggaa gcttctctct gtctgtcaga gactttgacc 1700

 ctgtgcatgg tgatgttatt aagcactaca aaattagaag tctggataat 1750

 gggggctatt acatctctcc acgaatcact tttccctgta tcagcgacat 1800

 gattaaacat taccaaaagc aggcagatgg cttgtgcaga agattggaga 1850

 aggcttgtat tagtcccaag ccacagaagc catgggataa agatgcctgg 1900

 gagatccccc gggagtccat caagttggtg aaaaggcttg gcgctgggca 1950

 gtttggggaa gtctggatgg gttactataa caacagtacc aaggtggctg 2000

 tgaaaaccct gaagccagga actatgtctg tgcaagcctt cctggaagaa 2050

 gccaacctca tgaagaccct gcagcatgac aagctcgtga ggctctacgc 2100

 tgtggtcacc agggaggagc ccatttacat catcaccgag tacatggcca 2150

 agggcagttt gctggatttc ctgaagagcg atgaaggtgg caaagtgctg 2200

 cttccaaagc tcattgactt ttctgctcag attgcagagg gaatggcata 2250

 catcgagcgg aagaactaca ttcaccggga cctgcgagca gctaatgttc 2300

 tggtctccga gtcactaatg tgcaaaattg cagattttgg ccttgctaga 2350

 gtaattgaag ataatgagta cacagcaagg gaaggtgcta agttccctat 2400

 taagtggacg gctccagaag caatcaactt tggatgtttc actattaagt 2450

 ctgatgtgtg gtcctttgga atcctcctat acgaaattgt cacctatggg 2500

 aaaattccct acccagggag aactaatgcc gacgtgatga ccgccctgtc 2550

 ccagggctac aggatgcccc gtgtggagaa ctgcccagat gagctctatg 2600

 acattatgaa aatgtgctgg aaagaaaagg cagaagagag accacggttg 2650

 actactacag agcgtcctgg atgattctac acagccacgg aagggcaata 2700

 ccagcagcag ccttagagca cagggagacc cgtccatatt ggcacagggt 2750

 ggctgcctca tttagagagg aaaagttaac cacatcactg gttgcactta 2800

 tgatttcatg tgcggggatc atctgccgtg cctggatcct gaaatagagg 2850

 ctaaattact caggaagaac accctctaaa tgggaaagta ttctgtactc 2900

 ttagatggat tctccactca gttgcaactt ggacttgtcc tcagcagctg 2950

 gtgaatcttg ctctgcttga ccaacatctg agtgcagccg tttgagaaga 3000

 aaacatctat tctctccaaa aatgcaccca actagctcta tgtttacaaa 3050

 tggacatagg actcaaagtt tcagagacca ttgcaatgaa tccccaataa 3100

 ttgcagaact aaactcattt ataaagctaa aataaccgga tatatacata 3150

 gcatgacatt tctttgtgct ttggcttact tgtttaagag accattgcaa 3200

 tgaatcccca ataattgcag aactaaactc atttataaag ctaaaataac 3250

 cggatatata catagcatga catttctttg tgctttggct tacttgttta 3300

 aaaaaaaaaa aaaactaatc caacctgtta gattttgcag gtgaagtcag 3350

 cagcttaaaa atgtctttcc cagatttcaa tgattttttt ccccctacct 3400

 cccaaaatct gagactgtta aaacattttt cttctatgaa cactgctcag 3450

 acctgctaga catgccatag gagtggcgtg cacatctctc tctcttccag 3500

 caggaggagc ccgtgagcac gcacagctgc cctgtctgct cacccgaagg 3550

 caccgggctc acctggacct cccaggaaag ggagaagagc ctcagaaact 3600

 gctctgtgtt tagaaggaat atttttaaga gtccagcttt ttcatttcca 3650

 caatttccta tatccagatt tgttttgaca atgtagtttg gaagaactaa 3700

 gattctaatc tctgaagaac cttatagggc cttctaaaac ataagagttt 3750

 cctttgttgc ttcaaatatt tgaacattat gttaaagatc aagtattaat 3800

 tttagttgta ctctagaaag ctaaagtgcc acattcgggg ctatttttat 3850

 gattcagcaa tcttttctaa attgtgtagc atgtgtatga gactatttat 3900

 acccaaggat atgaaggaac ataagtgact acaaggctct aataagccac 3950

 ggtggcagga ggttcaagcg gttctgttca ctaaattttt ctcctgtaag 4000

 ctttgaatgg aaacttctgt atcacatgat gtgtttcact tatgctgttg 4050

 tgtatatacc taatatttct atttttgatt ttattttaat acacctcgtc 4100

 caataacatc tcaagctttt tatttgcatt tacattttca gctgtggtca 4150

 gtgtaaaaat tggtcatcag ctgggggcgg ggtggttaga agtgattcaa 4200

 cagagctaca tgctttaaac ttgcctaagt tctacctcct tcctttgaac 4250

 atttcagatt ggagaaccaa ggagttgatt gcctgaacac ctgaacatcc 4300

 gtttatgggg gccagataga atttgttttc aaataggctt aacaggcatc 4350

 attaaaattt cattctgtgt gttttgttta ggcttgaggt gcttagaaga 4400

 tgggataaaa tattctactt ttttctaaat tttaactttg tttcctatgt 4450

 gattttttta aatgtccttt ctaaaatatt ctaaaattat tgattcacaa 4500

 gtgccatgtt cagaactata gaatattact gttacataat gtctgcacag 4550

 ctggtccctt gattcagtgg taaggttttt gtgtacaccc ccctgcttgc 4600

 attttatttc agaaccacaa gtattaccca atatgttaca tggagaggaa 4650

 ctataaagaa tccctaaggc aaaaagaagt ctctagaaaa tgactagagg 4700

 tttttttttt agcataacaa atttatttaa agaaaattat taaatttatc 4750

 ttcgccttaa aaaaa 4765

<210> 652
<211> 609
<212> PRT
<213> Homo sapien

<400> 652
 Met Gln Ile Arg Ala Pro Gly Ser Ser Trp Asp Leu Ser Ala Glu
   1               5                  10                  15

 Pro Arg Asp Ser Gln Phe Leu Ser Arg Arg Ala Gly Pro Arg Cys
                  20                  25                  30

 Arg Ser Leu Pro Gly Arg Gly Ala Ser Gly Pro Asp Ala Leu Gln
                  35                  40                  45

 Pro Pro Ala Arg Gly Lys Arg Ala Gly Arg Pro Arg His Pro Arg
                  50                  55                  60

 Pro Arg Ala Ser Ser Pro Ser Pro Arg Val Gln Arg Ser Arg Pro
                  65                  70                  75

 Ala Ala Ser Pro Tyr Ala Gly Pro Ala Gly Pro Pro Arg Arg Ala
                  80                  85                  90

 Pro His Ser Glu Leu Lys Ser Pro Trp Ser Ser Ala Ala Pro Lys
                  95                 100                 105

 Leu Ser Pro Arg Ala Gly Asn Met Gly Cys Ile Lys Ser Lys Gly
                 110                 115                 120

 Lys Asp Ser Leu Ser Asp Asp Gly Val Asp Leu Lys Thr Gln Pro
                 125                 130                 135

 Val Arg Asn Thr Glu Arg Thr Ile Tyr Val Arg Asp Pro Thr Ser
                 140                 145                 150

 Asn Lys Gln Gln Arg Pro Val Pro Glu Ser Gln Leu Leu Pro Gly
                 155                 160                 165

 Gln Arg Phe Gln Thr Lys Asp Pro Glu Glu Gln Gly Asp Ile Val
                 170                 175                 180

 Val Ala Leu Tyr Pro Tyr Asp Gly Ile His Pro Asp Asp Leu Ser
                 185                 190                 195

 Phe Lys Lys Gly Glu Lys Met Lys Val Leu Glu Glu His Gly Glu
                 200                 205                 210

 Trp Trp Lys Ala Lys Ser Leu Leu Thr Lys Lys Glu Gly Phe Ile
                 215                 220                 225

 Pro Ser Asn Tyr Val Ala Lys Leu Asn Thr Leu Glu Thr Glu Glu
                 230                 235                 240

 Trp Phe Phe Lys Asp Ile Thr Gly Lys Asp Ala Glu Arg Gln Leu
                 245                 250                 255

 Leu Ala Pro Gly Asn Ser Ala Gly Ala Phe Leu Ile Arg Glu Ser
                 260                 265                 270

 Glu Thr Leu Lys Gly Ser Phe Ser Leu Ser Val Arg Asp Phe Asp
                 275                 280                 285

 Pro Val His Gly Asp Val Ile Lys His Tyr Lys Ile Arg Ser Leu
                 290                 295                 300

 Asp Asn Gly Gly Tyr Tyr Ile Ser Pro Arg Ile Thr Phe Pro Cys
                 305                 310                 315

 Ile Ser Asp Met Ile Lys His Tyr Gln Lys Gln Ala Asp Gly Leu
                 320                 325                 330

 Cys Arg Arg Leu Glu Lys Ala Cys Ile Ser Pro Lys Pro Gln Lys
                 335                 340                 345

 Pro Trp Asp Lys Asp Ala Trp Glu Ile Pro Arg Glu Ser Ile Lys
                 350                 355                 360

 Leu Val Lys Arg Leu Gly Ala Gly Gln Phe Gly Glu Val Trp Met
                 365                 370                 375

 Gly Tyr Tyr Asn Asn Ser Thr Lys Val Ala Val Lys Thr Leu Lys
                 380                 385                 390

 Pro Gly Thr Met Ser Val Gln Ala Phe Leu Glu Glu Ala Asn Leu
                 395                 400                 405

 Met Lys Thr Leu Gln His Asp Lys Leu Val Arg Leu Tyr Ala Val
                 410                 415                 420

 Val Thr Arg Glu Glu Pro Ile Tyr Ile Ile Thr Glu Tyr Met Ala
                 425                 430                 435

 Lys Gly Ser Leu Leu Asp Phe Leu Lys Ser Asp Glu Gly Gly Lys
                 440                 445                 450

 Val Leu Leu Pro Lys Leu Ile Asp Phe Ser Ala Gln Ile Ala Glu
                 455                 460                 465

 Gly Met Ala Tyr Ile Glu Arg Lys Asn Tyr Ile His Arg Asp Leu
                 470                 475                 480

 Arg Ala Ala Asn Val Leu Val Ser Glu Ser Leu Met Cys Lys Ile
                 485                 490                 495

 Ala Asp Phe Gly Leu Ala Arg Val Ile Glu Asp Asn Glu Tyr Thr
                 500                 505                 510

 Ala Arg Glu Gly Ala Lys Phe Pro Ile Lys Trp Thr Ala Pro Glu
                 515                 520                 525

 Ala Ile Asn Phe Gly Cys Phe Thr Ile Lys Ser Asp Val Trp Ser
                 530                 535                 540

 Phe Gly Ile Leu Leu Tyr Glu Ile Val Thr Tyr Gly Lys Ile Pro
                 545                 550                 555

 Tyr Pro Gly Arg Thr Asn Ala Asp Val Met Thr Ala Leu Ser Gln
                 560                 565                 570

 Gly Tyr Arg Met Pro Arg Val Glu Asn Cys Pro Asp Glu Leu Tyr
                 575                 580                 585

 Asp Ile Met Lys Met Cys Trp Lys Glu Lys Ala Glu Glu Arg Pro
                 590                 595                 600

 Arg Leu Thr Thr Thr Glu Arg Pro Gly
                 605

<210> 653
<211> 2298
<212> DNA
<213> Homo sapien

<400> 653
 tcggccgagc ccagagacag ccagttcctc tcccgccgcg ccgggccgcg 50

 tgccgctcgc tccccggccg tggcgcctcc gggccagacg cgctgcagcc 100

 tccagcccgc ggcaagcggg cggggcggcc gcgccacccc cggccccgcg 150

 ccagcagccc ctcgccgcgc gtccagcgtt cccggccagc agcctcccca 200

 tacgcagtcc tgctggaccg ccccgtcgcg ccccccactc tgaactcaag 250

 tcaccgtgga gctccgccgc cccgaaactt tcacgcgagc gggaaatatg 300

 ggatgtataa aatcaaaagg gaaagacagc ttgagtgacg atggagtaga 350

 tttgaagact caaccagtac gtaatactga aagaactatt tatgtgagag 400

 atccaacgtc caataaacag caaaggccag ttccagaatc tcagctttta 450

 cctggacaga ggtttcaaac taaagatcca gaggaacaag gagacattgt 500

 ggtagccttg tacccctatg atggcatcca cccggacgac ttgtctttca 550

 agaaaggaga gaagatgaaa gtcctggagg agcatggaga atggtggaaa 600

 gcaaagtccc ttttaacaaa aaaagaaggc ttcatcccca gcaactatgt 650

 ggccaaactc aacaccttag aaacagaaga gtggtttttc aaggatataa 700

 ccaggaagga cgcagaaagg cagcttttgg caccaggaaa tagcgctgga 750

 gctttcctta ttagagaaag tgaaacatta aaaggaagct tctctctgtc 800

 tgtcagagac tttgaccctg tgcatggtga tgttattaag cactacaaaa 850

 ttagaagtct ggataatggg ggctattaca tctctccacg aatcactttt 900

 ccctgtatca gcgacatgat taaacattac caaaagcagg cagatggctt 950

 gtgcagaaga ttggagaagg cttgtattag tcccaagcca cagaagccat 1000

 gggataaaga tgcctgggag atcccccggg agtccatcaa gttggtgaaa 1050

 aggcttggcg ctgggcagtt tggggaagtc tggatgggtt actataacaa 1100

 cagtaccaag gtggctgtga aaaccctgaa gccaggaact atgtctgtgc 1150

 aagccttcct ggaagaagcc aacctcatga agaccctgca gcatgacaag 1200

 ctcgtgaggc tctacgctgt ggtcaccagg gaggagccca tttacatcat 1250

 caccgagtac atggccaagg gcagtttgct ggatttcctg aagagcgatg 1300

 aaggtggcaa agtgctgctt ccaaagctca ttgacttttc tgctcagatt 1350

 gcagagggaa tggcatacat cgagcggaag aactacattc accgggacct 1400

 gcgagcagct aatgttctgg tctccgagtc actaatgtgc aaaattgcag 1450

 attttggcct tgctagagta attgaagata atgagtacac agcaagggaa 1500

 ggtgctaagt tccctattaa gtggacggct ccagaagcaa tcaactttgg 1550

 atgtttcact attaagtctg atgtgtggtc ctttggaatc ctcctatacg 1600

 aaattgtcac ctatgggaaa attccctacc cagggagaac taatgccgac 1650

 gtgatgaccg ccctgtccca gggctacagg atgccccgtg tggagaactg 1700

 cccagatgag ctctatgaca ttatgaaaat gtgctggaaa gaaaaggcag 1750

 aagagagacc aacgtttgac tacttacaga gcgtcctgga tgatttctac 1800

 acagccacgg aagggcaata ccagcagcag ccttagagca cagggagacc 1850

 cgtccatttg gcaggggtgg ctgcctcatt tagagaggaa aagtaaccat 1900

 cactggttgc acttatgatt tcatgtgcgg ggatcatctg ccgtgcctgg 1950

 atcctgaaat agaggctaaa ttactcagga agaacaccct ctaaatggga 2000

 aagtattctg tactcttaga tggattctcc actcagttgc aacttggact 2050

 tgtcctcagc agctggtaat cttgctctgc ttgacaacat ctgagtgcag 2100

 ccgtttgaga agaaaacatc tattctctcc aaaaatgcac ccaactagct 2150

 ctatgtttac aaatggacat aggactcaaa gtttcagaga ccattgcaat 2200

 gaatccccaa taattgcaga actaaactca tttataaagc taaaataacc 2250

 ggatatatac atagcatgac atttctttgt gctttggctt acttgttt 2298

<210> 654
<211> 512
<212> PRT
<213> Homo sapien

<400> 654
 Met Gly Cys Ile Lys Ser Lys Gly Lys Asp Ser Leu Ser Asp Asp
   1               5                  10                  15

 Gly Val Asp Leu Lys Thr Gln Pro Val Arg Asn Thr Glu Arg Thr
                  20                  25                  30

 Ile Tyr Val Arg Asp Pro Thr Ser Asn Lys Gln Gln Arg Pro Val
                  35                  40                  45

 Pro Glu Ser Gln Leu Leu Pro Gly Gln Arg Phe Gln Thr Lys Asp
                  50                  55                  60

 Pro Glu Glu Gln Gly Asp Ile Val Val Ala Leu Tyr Pro Tyr Asp
                  65                  70                  75

 Gly Ile His Pro Asp Asp Leu Ser Phe Lys Lys Gly Glu Lys Met
                  80                  85                  90

 Lys Val Leu Glu Glu His Gly Glu Trp Trp Lys Ala Lys Ser Leu
                  95                 100                 105

 Leu Thr Lys Lys Glu Gly Phe Ile Pro Ser Asn Tyr Val Ala Lys
                 110                 115                 120

 Leu Asn Thr Leu Glu Thr Glu Glu Trp Phe Phe Lys Asp Ile Thr
                 125                 130                 135

 Arg Lys Asp Ala Glu Arg Gln Leu Leu Ala Pro Gly Asn Ser Ala
                 140                 145                 150

 Gly Ala Phe Leu Ile Arg Glu Ser Glu Thr Leu Lys Gly Ser Phe
                 155                 160                 165

 Ser Leu Ser Val Arg Asp Phe Asp Pro Val His Gly Asp Val Ile
                 170                 175                 180

 Lys His Tyr Lys Ile Arg Ser Leu Asp Asn Gly Gly Tyr Tyr Ile
                 185                 190                 195

 Ser Pro Arg Ile Thr Phe Pro Cys Ile Ser Asp Met Ile Lys His
                 200                 205                 210

 Tyr Gln Lys Gln Ala Asp Gly Leu Cys Arg Arg Leu Glu Lys Ala
                 215                 220                 225

 Cys Ile Ser Pro Lys Pro Gln Lys Pro Trp Asp Lys Asp Ala Trp
                 230                 235                 240

 Glu Ile Pro Arg Glu Ser Ile Lys Leu Val Lys Arg Leu Gly Ala
                 245                 250                 255

 Gly Gln Phe Gly Glu Val Trp Met Gly Tyr Tyr Asn Asn Ser Thr
                 260                 265                 270

 Lys Val Ala Val Lys Thr Leu Lys Pro Gly Thr Met Ser Val Gln
                 275                 280                 285

 Ala Phe Leu Glu Glu Ala Asn Leu Met Lys Thr Leu Gln His Asp
                 290                 295                 300

 Lys Leu Val Arg Leu Tyr Ala Val Val Thr Arg Glu Glu Pro Ile
                 305                 310                 315

 Tyr Ile Ile Thr Glu Tyr Met Ala Lys Gly Ser Leu Leu Asp Phe
                 320                 325                 330

 Leu Lys Ser Asp Glu Gly Gly Lys Val Leu Leu Pro Lys Leu Ile
                 335                 340                 345

 Asp Phe Ser Ala Gln Ile Ala Glu Gly Met Ala Tyr Ile Glu Arg
                 350                 355                 360

 Lys Asn Tyr Ile His Arg Asp Leu Arg Ala Ala Asn Val Leu Val
                 365                 370                 375

 Ser Glu Ser Leu Met Cys Lys Ile Ala Asp Phe Gly Leu Ala Arg
                 380                 385                 390

 Val Ile Glu Asp Asn Glu Tyr Thr Ala Arg Glu Gly Ala Lys Phe
                 395                 400                 405

 Pro Ile Lys Trp Thr Ala Pro Glu Ala Ile Asn Phe Gly Cys Phe
                 410                 415                 420

 Thr Ile Lys Ser Asp Val Trp Ser Phe Gly Ile Leu Leu Tyr Glu
                 425                 430                 435

 Ile Val Thr Tyr Gly Lys Ile Pro Tyr Pro Gly Arg Thr Asn Ala
                 440                 445                 450

 Asp Val Met Thr Ala Leu Ser Gln Gly Tyr Arg Met Pro Arg Val
                 455                 460                 465

 Glu Asn Cys Pro Asp Glu Leu Tyr Asp Ile Met Lys Met Cys Trp
                 470                 475                 480

 Lys Glu Lys Ala Glu Glu Arg Pro Thr Phe Asp Tyr Leu Gln Ser
                 485                 490                 495

 Val Leu Asp Asp Phe Tyr Thr Ala Thr Glu Gly Gln Tyr Gln Gln
                 500                 505                 510

 Gln Pro


<210> 655
<211> 540
<212> DNA
<213> Homo sapien

<400> 655
 cctggactag ccgggttgta tttggaaacg cggagtgagt ttttccgtgc 50

 tgtgtagggg ctaacaatgg acacccagaa ggacgttcaa cctccaaagc 100

 agcaaccaat gatatatatc tgtggagagt gtcacacaga aaatgaaata 150

 aaatctaggg atccaatcag atgcagagaa tgtggataca gaataatgta 200

 caagaaaagg actaaaagat tggtcgtttt tgatgctcga tgaatgctgg 250

 gaattcagag gaatgtcttc acttatactt ggatttgctc tcttcccatt 300

 tctgattgtt gtatagcttt cgattttgct tacagtagtt cccccttatc 350

 ttcgggagat acattccaag gcccccagtg aactcctgaa acctcaaaca 400

 gtaccaaacc tttatacact gttttttcca tatatatata cctatgataa 450

 agtataatgt ataaattaag catagcaaga gattaataat aatgtaatag 500

 aacaatgata acatactata ataaaagtta tgtgaatgtg 540

<210> 656
<211> 58
<212> PRT
<213> Homo sapien

<400> 656
 Met Asp Thr Gln Lys Asp Val Gln Pro Pro Lys Gln Gln Pro Met
   1               5                  10                  15

 Ile Tyr Ile Cys Gly Glu Cys His Thr Glu Asn Glu Ile Lys Ser
                  20                  25                  30

 Arg Asp Pro Ile Arg Cys Arg Glu Cys Gly Tyr Arg Ile Met Tyr
                  35                  40                  45

 Lys Lys Arg Thr Lys Arg Leu Val Val Phe Asp Ala Arg
                  50                  55

<210> 657
<211> 2986
<212> DNA
<213> Homo sapien

<400> 657
 gcgccccagt cgacgctgag ctcctctgct actcagagtt gcaacctcag 50

 cctcgctatg gctcccagca gcccccggcc cgcgctgccc gcactcctgg 100

 tcctgctcgg ggctctgttc ccaggacctg gcaatgccca gacatctgtg 150

 tccccctcaa aagtcatcct gccccgggga ggctccgtgc tggtgacatg 200

 cagcacctcc tgtgaccagc ccaagttgtt gggcatagag accccgttgc 250

 ctaaaaagga gttgctcctg cctgggaaca accggaaggt gtatgaactg 300

 agcaatgtgc aagaagatag ccaaccaatg tgctattcaa actgccctga 350

 tgggcagtca acagctaaaa ccttcctcac cgtgtactgg actccagaac 400

 gggtggaact ggcacccctc ccctcttggc agccagtggg caagaacctt 450

 accctacgct gccaggtgga gggtggggca ccccgggcca acctcaccgt 500

 ggtgctgctc cgtggggaga aggagctgaa acgggagcca gctgtggggg 550

 agcccgctga ggtcacgacc acggtgctgg tgaggagaga tcaccatgga 600

 gccaatttct cgtgccgcac tgaactggac ctgcggcccc aagggctgga 650

 gctgtttgag aacacctcgg ccccctacca gctccagacc tttgtcctgc 700

 cagcgactcc cccacaactt gtcagccccc gggtcctaga ggtggacacg 750

 caggggaccg tggtctgttc cctggacggg ctgttcccag tctcggaggc 800

 ccaggtccac ctggcactgg gggaccagag gttgaacccc acagtcacct 850

 atggcaacga ctccttctcg gccaaggcct cagtcagtgt gaccgcagag 900

 gacgagggca cccagcggct gacgtgtgca gtaatactgg ggaaccagag 950

 ccaggagaca ctgcagacag tgaccatcta cagctttccg gcgcccaacg 1000

 tgattctgac gaagccagag gtctcagaag ggaccgaggt gacagtgaag 1050

 tgtgaggccc accctagagc caaggtgacg ctgaatgggg ttccagccca 1100

 gccactgggc ccgagggccc agctcctgct gaaggccacc ccagaggaca 1150

 acgggcgcag cttctcctgc tctgcaaccc tggaggtggc cggccagctt 1200

 atacacaaga accagacccg ggagcttcgt gtcctgtatg gcccccgact 1250

 ggacgagagg gattgtccgg gaaactggac gtggccagaa aattcccagc 1300

 agactccaat gtgccaggct tgggggaacc cattgcccga gctcaagtgt 1350

 ctaaaggatg gcactttccc actgcccatc ggggaatcag tgactgtcac 1400

 tcgagatctt gagggcacct acctctgtcg ggccaggagc actcaagggg 1450

 aggtcacccg cgaggtgacc gtgaatgtgc tctccccccg gtatgagatt 1500

 gtcatcatca ctgtggtagc agccgcagtc ataatgggca ctgcaggcct 1550

 cagcacgtac ctctataacc gccagcggaa gatcaagaaa tacagactac 1600

 aacaggccca aaaagggacc cccatgaaac cgaacacaca agccacgcct 1650

 ccctgaacct atcccgggac agggcctctt cctcggcctt cccatattgg 1700

 tggcagtggt gccacactga acagagtgga agacatatgc catgcagcta 1750

 cacctaccgg ccctgggacg ccggaggaca gggcattgtc ctcagtcaga 1800

 tacaacagca tttggggcca tggtacctgc acacctaaaa cactaggcca 1850

 cgcatctgat ctgtagtcac atgactaagc caagaggaag gagcaagact 1900

 caagacatga ttgatggatg ttaaagtcta gcctgatgag aggggaagtg 1950

 gtgggggaga catagcccca ccatgaggac atacaactgg gaaatactga 2000

 aacttgctgc ctattgggta tgctgaggcc cacagactta cagaagaagt 2050

 ggccctccat agacatgtgt agcatcaaaa cacaaaggcc cacacttcct 2100

 gacggatgcc agcttgggca ctgctgtcta ctgaccccaa cccttgatga 2150

 tatgtattta ttcatttgtt attttaccag ctatttattg agtgtctttt 2200

 atgtaggcta aatgaacata ggtctctggc ctcacggagc tcccagtcca 2250

 tgtcacattc aaggtcacca ggtacagttg tacaggttgt acactgcagg 2300

 agagtgcctg gcaaaaagat caaatggggc tgggacttct cattggccaa 2350

 cctgcctttc cccagaagga gtgatttttc tatcggcaca aaagcactat 2400

 atggactggt aatggttcac aggttcagag attacccagt gaggccttat 2450

 tcctcccttc cccccaaaac tgacaccttt gttagccacc tccccaccca 2500

 catacatttc tgccagtgtt cacaatgaca ctcagcggtc atgtctggac 2550

 atgagtgccc agggaatatg cccaagctat gccttgtcct cttgtcctgt 2600

 ttgcatttca ctgggagctt gcactattgc agctccagtt tcctgcagtg 2650

 atcagggtcc tgcaagcagt ggggaagggg gccaaggtat tggaggactc 2700

 cctcccagct ttggaagggt catccgcgtg tgtgtgtgtg tgtatgtgta 2750

 gacaagctct cgctctgtca cccaggctgg agtgcagtgg tgcaatcatg 2800

 gttcactgca gtcttgacct tttgggctca agtgatcctc ccacctcagc 2850

 ctcctgagta gctgggacca taggctcaca acaccacacc tggcaaattt 2900

 gatttttttt ttttttttca gagacggggt ctcgcaacat tgcccagact 2950

 tcctttgtgt tagttaataa agctttctca actgcc 2986

<210> 658
<211> 532
<212> PRT
<213> Homo sapien

<400> 658
 Met Ala Pro Ser Ser Pro Arg Pro Ala Leu Pro Ala Leu Leu Val
   1               5                  10                  15

 Leu Leu Gly Ala Leu Phe Pro Gly Pro Gly Asn Ala Gln Thr Ser
                  20                  25                  30

 Val Ser Pro Ser Lys Val Ile Leu Pro Arg Gly Gly Ser Val Leu
                  35                  40                  45

 Val Thr Cys Ser Thr Ser Cys Asp Gln Pro Lys Leu Leu Gly Ile
                  50                  55                  60

 Glu Thr Pro Leu Pro Lys Lys Glu Leu Leu Leu Pro Gly Asn Asn
                  65                  70                  75

 Arg Lys Val Tyr Glu Leu Ser Asn Val Gln Glu Asp Ser Gln Pro
                  80                  85                  90

 Met Cys Tyr Ser Asn Cys Pro Asp Gly Gln Ser Thr Ala Lys Thr
                  95                 100                 105

 Phe Leu Thr Val Tyr Trp Thr Pro Glu Arg Val Glu Leu Ala Pro
                 110                 115                 120

 Leu Pro Ser Trp Gln Pro Val Gly Lys Asn Leu Thr Leu Arg Cys
                 125                 130                 135

 Gln Val Glu Gly Gly Ala Pro Arg Ala Asn Leu Thr Val Val Leu
                 140                 145                 150

 Leu Arg Gly Glu Lys Glu Leu Lys Arg Glu Pro Ala Val Gly Glu
                 155                 160                 165

 Pro Ala Glu Val Thr Thr Thr Val Leu Val Arg Arg Asp His His
                 170                 175                 180

 Gly Ala Asn Phe Ser Cys Arg Thr Glu Leu Asp Leu Arg Pro Gln
                 185                 190                 195

 Gly Leu Glu Leu Phe Glu Asn Thr Ser Ala Pro Tyr Gln Leu Gln
                 200                 205                 210

 Thr Phe Val Leu Pro Ala Thr Pro Pro Gln Leu Val Ser Pro Arg
                 215                 220                 225

 Val Leu Glu Val Asp Thr Gln Gly Thr Val Val Cys Ser Leu Asp
                 230                 235                 240

 Gly Leu Phe Pro Val Ser Glu Ala Gln Val His Leu Ala Leu Gly
                 245                 250                 255

 Asp Gln Arg Leu Asn Pro Thr Val Thr Tyr Gly Asn Asp Ser Phe
                 260                 265                 270

 Ser Ala Lys Ala Ser Val Ser Val Thr Ala Glu Asp Glu Gly Thr
                 275                 280                 285

 Gln Arg Leu Thr Cys Ala Val Ile Leu Gly Asn Gln Ser Gln Glu
                 290                 295                 300

 Thr Leu Gln Thr Val Thr Ile Tyr Ser Phe Pro Ala Pro Asn Val
                 305                 310                 315

 Ile Leu Thr Lys Pro Glu Val Ser Glu Gly Thr Glu Val Thr Val
                 320                 325                 330

 Lys Cys Glu Ala His Pro Arg Ala Lys Val Thr Leu Asn Gly Val
                 335                 340                 345

 Pro Ala Gln Pro Leu Gly Pro Arg Ala Gln Leu Leu Leu Lys Ala
                 350                 355                 360

 Thr Pro Glu Asp Asn Gly Arg Ser Phe Ser Cys Ser Ala Thr Leu
                 365                 370                 375

 Glu Val Ala Gly Gln Leu Ile His Lys Asn Gln Thr Arg Glu Leu
                 380                 385                 390

 Arg Val Leu Tyr Gly Pro Arg Leu Asp Glu Arg Asp Cys Pro Gly
                 395                 400                 405

 Asn Trp Thr Trp Pro Glu Asn Ser Gln Gln Thr Pro Met Cys Gln
                 410                 415                 420

 Ala Trp Gly Asn Pro Leu Pro Glu Leu Lys Cys Leu Lys Asp Gly
                 425                 430                 435

 Thr Phe Pro Leu Pro Ile Gly Glu Ser Val Thr Val Thr Arg Asp
                 440                 445                 450

 Leu Glu Gly Thr Tyr Leu Cys Arg Ala Arg Ser Thr Gln Gly Glu
                 455                 460                 465

 Val Thr Arg Glu Val Thr Val Asn Val Leu Ser Pro Arg Tyr Glu
                 470                 475                 480

 Ile Val Ile Ile Thr Val Val Ala Ala Ala Val Ile Met Gly Thr
                 485                 490                 495

 Ala Gly Leu Ser Thr Tyr Leu Tyr Asn Arg Gln Arg Lys Ile Lys
                 500                 505                 510

 Lys Tyr Arg Leu Gln Gln Ala Gln Lys Gly Thr Pro Met Lys Pro
                 515                 520                 525

 Asn Thr Gln Ala Thr Pro Pro
                 530

<210> 659
<211> 900
<212> DNA
<213> Homo sapien

<400> 659
 gggactcggc ggaggatggg cttgctctca attttgcgca agttgaaaag 50

 tgcaccagac caggaggtga gaatacttct cctgggcttg gataatgctg 100

 gcaagaccac tcttctgaag cagcttgcat ctgaagacat cagccacatc 150

 acacctacac agggtttcaa catcaaaagt gtacaatcac aaggttttaa 200

 actgaatgta tgggacattg gtggacagag gaaaatcaga ccatactgga 250

 agaattattt tgaaaatacc gatattctta tatatgtaat cgacagtgca 300

 gacagaaaaa gatttgaaga gacgggtcag gaactagcgg aattactgga 350

 ggaagaaaaa ctaagttgtg tgccagtgct catctttgct aataagcagg 400

 atttgctcac agcagcccct gcctctgaaa ttgcagaagg actgaacctg 450

 cataccatcc gcgaccgagt ctggcagatc cagtcttgct cagctctcac 500

 aggagagggc gttcaggatg gcatgaactg ggtctgcaaa aatgtcaatg 550

 caaagaagaa ataaaatcta gacgaatgga gatgcaggag ctgcgggagc 600

 cgaattcggg ccttaaaaac actaatttgc tgctttctga ccaaatgttt 650

 ttcatctgtg tacactccag ctgtttgaag agagggaaca acacggttta 700

 gaaagaatcc ccattccagc agtagattta actgatctct gaggttcagt 750

 atcatttttc aaataaagga attatattat ttcctctgca taattgaaat 800

 agtattaaat gtctaaagca catgattaga aaatgagatc ttttaaatga 850

 gcaagagatt gcattgcagt ttagacaatt ccagtgggct ttttttttcg 900

<210> 660
<211> 182
<212> PRT
<213> Homo sapien

<400> 660
 Met Gly Leu Leu Ser Ile Leu Arg Lys Leu Lys Ser Ala Pro Asp
   1               5                  10                  15

 Gln Glu Val Arg Ile Leu Leu Leu Gly Leu Asp Asn Ala Gly Lys
                  20                  25                  30

 Thr Thr Leu Leu Lys Gln Leu Ala Ser Glu Asp Ile Ser His Ile
                  35                  40                  45

 Thr Pro Thr Gln Gly Phe Asn Ile Lys Ser Val Gln Ser Gln Gly
                  50                  55                  60

 Phe Lys Leu Asn Val Trp Asp Ile Gly Gly Gln Arg Lys Ile Arg
                  65                  70                  75

 Pro Tyr Trp Lys Asn Tyr Phe Glu Asn Thr Asp Ile Leu Ile Tyr
                  80                  85                  90

 Val Ile Asp Ser Ala Asp Arg Lys Arg Phe Glu Glu Thr Gly Gln
                  95                 100                 105

 Glu Leu Ala Glu Leu Leu Glu Glu Glu Lys Leu Ser Cys Val Pro
                 110                 115                 120

 Val Leu Ile Phe Ala Asn Lys Gln Asp Leu Leu Thr Ala Ala Pro
                 125                 130                 135

 Ala Ser Glu Ile Ala Glu Gly Leu Asn Leu His Thr Ile Arg Asp
                 140                 145                 150

 Arg Val Trp Gln Ile Gln Ser Cys Ser Ala Leu Thr Gly Glu Gly
                 155                 160                 165

 Val Gln Asp Gly Met Asn Trp Val Cys Lys Asn Val Asn Ala Lys
                 170                 175                 180

 Lys Lys


<210> 661
<211> 4446
<212> DNA
<213> Homo sapien

<400> 661
 tgccttgacc aggacttggg actttgcgaa aggatcgcgg ggcccggaga 50

 ggtgttggag agcacaatgg ctgaacaagt ccttcctcag gctttgtatt 100

 tgagcaatat gcggaaagct gtgaagatac gggagagaac tccagaagac 150

 atttttaaac ctactaatgg gatcattcat cattttaaaa ccatgcaccg 200

 atacacactg gaaatgttca gaacttgcca gttttgtcct cagtttcggg 250

 agatcatcca caaagccctc atcgacagaa acatccaggc caccctggaa 300

 agccagaaga aactcaactg gtgtcgagaa gtccggaagc ttgtggcgct 350

 gaaaacgaac ggtgacggca attgcctcat gcatgccact tctcagtaca 400

 tgtggggcgt tcaggacaca gacttggtac tgaggaaggc gctgttcagc 450

 acgctcaagg aaacagacac acgcaacttt aaattccgct ggcaactgga 500

 gtctctcaaa tctcaggaat ttgttgaaac ggggctttgc tatgatactc 550

 ggaactggaa tgatgaatgg gacaatctta tcaaaatggc ttccacagac 600

 acacccatgg cccgaagtgg acttcagtac aactcactgg aagaaataca 650

 catatttgtc ctttgcaaca tcctcagaag gccaatcatt gtcatttcag 700

 acaaaatgct aagaagtttg gaatcaggtt ccaatttcgc ccctttgaaa 750

 gtgggtggaa tttacttgcc tctccactgg cctgcccagg aatgctacag 800

 ataccccatt gttctcggct atgacagcca tcattttgta cccttggtga 850

 ccctgaagga cagtgggcct gaaatccgag ctgttccact tgttaacaga 900

 gaccggggaa gatttgaaga cttaaaagtt cactttttga cagatcctga 950

 aaatgagatg aaggagaagc tcttaaaaga gtacttaatg gtgatagaaa 1000

 tccccgtcca aggctgggac catggcacaa ctcatctcat caatgccgca 1050

 aagttggatg aagctaactt accaaaagaa atcaatctgg tagatgatta 1100

 ctttgaactt gttcagcatg agtacaagaa atggcaggaa aacagcgagc 1150

 aggggaggag agaggggcac gcccagaatc ccatggaacc ttccgtgccc 1200

 cagctttctc tcatggatgt aaaatgtgaa acgcccaact gccccttctt 1250

 catgtctgtg aacacccagc ctttatgcca tgagtgctca gagaggcggc 1300

 aaaagaatca aaacaaactc ccaaagctga actccaagcc gggccctgag 1350

 gggctccctg gcatggcgct cggggcctct cggggagaag cctatgagcc 1400

 cttggcgtgg aaccctgagg agtccactgg ggggcctcat tcggccccac 1450

 cgacagcacc cagccctttt ctgttcagtg agaccactgc catgaagtgc 1500

 aggagccccg gctgcccctt cacactgaat gtgcagcaca acggattttg 1550

 tgaacgttgc cacaacgccc ggcaacttca cgccagccac gccccagacc 1600

 acacaaggca cttggatccc gggaagtgcc aagcctgcct ccaggatgtt 1650

 accaggacat ttaatgggat ctgcagtact tgcttcaaaa ggactacagc 1700

 agaggcctcc tccagcctca gcaccagcct ccctccttcc tgtcaccagc 1750

 gttccaagtc agatccctcg cggctcgtcc ggagcccctc cccgcattct 1800

 tgccacagag ctggaaacga cgcccctgct ggctgcctgt ctcaagctgc 1850

 acggactcct ggggacagga cggggacgag caagtgcaga aaagccggct 1900

 gcgtgtattt tgggactcca gaaaacaagg gcttttgcac actgtgtttc 1950

 atcgagtaca gagaaaacaa acattttgct gctgcctcag ggaaagtcag 2000

 tcccacagcg tccaggttcc agaacaccat tccgtgcctg gggagggaat 2050

 gcggcaccct tggaagcacc atgtttgaag gatactgcca gaagtgtttc 2100

 attgaagctc agaatcagag atttcatgag gccaaaagga cagaagagca 2150

 actgagatcg agccagcgca gagatgtgcc tcgaaccaca caaagcacct 2200

 caaggcccaa gtgcgcccgg gcctcctgca agaacatcct ggcctgccgc 2250

 agcgaggagc tctgcatgga gtgtcagcat cccaaccaga ggatgggccc 2300

 tggggcccac cggggtgagc ctgcccccga agaccccccc aagcagcgtt 2350

 gccgggcccc cgcctgtgat cattttggca atgccaagtg caacggctac 2400

 tgcaacgaat gctttcagtt caagcagatg tatggctaac cggaaacagg 2450

 tgggtcacct cctgcaagaa gtggggcctc gagctgtcag tcatcatggt 2500

 gctatcctct gaacccctca gctgccactg caacagtggg cttaagggtg 2550

 tctgagcagg agaggaaaga taagctcttc gtggtgccca cgatgctcag 2600

 gtttggtaac ccgggagtgt tcccaggtgg ccttagaaag caaagcttgt 2650

 aactggcaag ggatgatgtc agattcagcc caaggttcct cctctcctac 2700

 caagcaggag gccaggaact tctttggact tggaaggtgt gcggggactg 2750

 gccgaggccc ctgcaccctg cgcatcagga ctgcttcatc gtcttggctg 2800

 agaaagggaa aagacacaca agtcgcgtgg gttggagaag ccagagccat 2850

 tccacctccc ctcccccagc atctctcaga gatgtgaagc cagatcctca 2900

 tggcagcgag gccctctgca agaagctcaa ggaagctcag ggaaaatgga 2950

 cgtattcaga gagtgtttgt agttcatggt ttttccctac ctgcccggtt 3000

 cctttcctga ggacccggca gaaatgcaga accatccatg gactgtgatt 3050

 ctgaggctgc tgagactgaa catgttcaca ttgacagaaa aacaagctgc 3100

 tctttataat atgcaccttt taaaaaatta gaatatttta ctgggaagac 3150

 gtgtaactct ttgggttatt actgtcttta cttctaaaga agttagcttg 3200

 aactgaggag taaaagtgtg tacatatata atataccctt acattatgta 3250

 tgagggattt ttttaaatta tattgaaatg ctgccctaga agtacaatag 3300

 gaaggctaaa taataataac ctgttttctg gttgttgttg gggcatgagc 3350

 ttgtgtatac actgcttgca taaactcaac cagctgcctt tttaaaggga 3400

 gctctagtcc tttttgtgta attcacttta tttattttat tacaaacttc 3450

 aagattattt aagtgaagat atttcttcag ctctggggaa aatgccacag 3500

 tgttctcctg agagaacatc cttgctttga gtcaggctgt gggcaagttc 3550

 ctgaccacag ggagtaaatt ggcctctttg atacactttt gcttgcctcc 3600

 ccaggaaaga aggaattgca tccaaggtat acatacatat tcatcgatgt 3650

 ttcgtgcttc tccttatgaa actccagcta tgtaataaaa aactatactc 3700

 tgtgttctgt taatgcctct gagtgtccta cctccttgga gatgagatag 3750

 ggaaggagca gggatgagac tggcaatggt cacagggaaa gatgtggcct 3800

 tttgtgatgg ttttattttc tgttaacact gtgtcctggg ggggctggga 3850

 agtcccctgc atcccatggt accctggtat tgggacagca aaagccagta 3900

 accatgagta tgaggaaatc tctttctgtt gctggcttac agtttctctg 3950

 tgtgctttgt ggttgctgtc atatttgctc tagaagaaaa aaaaaaaagg 4000

 aggggaaatg cattttcccc agagataaag gctgccattt tgggggtctg 4050

 tacttatggc ctgaaaatat ttgtgatcca taactctaca cagcctttac 4100

 tcatactatt aggcacactt tccccttaga gccccctaag tttttcccag 4150

 acgaatcttt ataatttctt tccaaagata ccaaataaac ttcagtgttt 4200

 tcatctaatt ctcttaaagt tgatatctta atattttgtg ttgatcatta 4250

 tttccattct taatgtgaaa aaaagtaatt atttatactt attataaaaa 4300

 gtatttgaaa tttgcacatt taattgtccc taatagaaag ccacctattc 4350

 tttgttggat ttcttcaagt ttttctaaat aaatgtaact tttcacaaga 4400

 gtcaacatta aaaaataaat tatttaagaa caaaaaaaaa aaaaaa 4446

<210> 662
<211> 790
<212> PRT
<213> Homo sapien

<400> 662
 Met Ala Glu Gln Val Leu Pro Gln Ala Leu Tyr Leu Ser Asn Met
   1               5                  10                  15

 Arg Lys Ala Val Lys Ile Arg Glu Arg Thr Pro Glu Asp Ile Phe
                  20                  25                  30

 Lys Pro Thr Asn Gly Ile Ile His His Phe Lys Thr Met His Arg
                  35                  40                  45

 Tyr Thr Leu Glu Met Phe Arg Thr Cys Gln Phe Cys Pro Gln Phe
                  50                  55                  60

 Arg Glu Ile Ile His Lys Ala Leu Ile Asp Arg Asn Ile Gln Ala
                  65                  70                  75

 Thr Leu Glu Ser Gln Lys Lys Leu Asn Trp Cys Arg Glu Val Arg
                  80                  85                  90

 Lys Leu Val Ala Leu Lys Thr Asn Gly Asp Gly Asn Cys Leu Met
                  95                 100                 105

 His Ala Thr Ser Gln Tyr Met Trp Gly Val Gln Asp Thr Asp Leu
                 110                 115                 120

 Val Leu Arg Lys Ala Leu Phe Ser Thr Leu Lys Glu Thr Asp Thr
                 125                 130                 135

 Arg Asn Phe Lys Phe Arg Trp Gln Leu Glu Ser Leu Lys Ser Gln
                 140                 145                 150

 Glu Phe Val Glu Thr Gly Leu Cys Tyr Asp Thr Arg Asn Trp Asn
                 155                 160                 165

 Asp Glu Trp Asp Asn Leu Ile Lys Met Ala Ser Thr Asp Thr Pro
                 170                 175                 180

 Met Ala Arg Ser Gly Leu Gln Tyr Asn Ser Leu Glu Glu Ile His
                 185                 190                 195

 Ile Phe Val Leu Cys Asn Ile Leu Arg Arg Pro Ile Ile Val Ile
                 200                 205                 210

 Ser Asp Lys Met Leu Arg Ser Leu Glu Ser Gly Ser Asn Phe Ala
                 215                 220                 225

 Pro Leu Lys Val Gly Gly Ile Tyr Leu Pro Leu His Trp Pro Ala
                 230                 235                 240

 Gln Glu Cys Tyr Arg Tyr Pro Ile Val Leu Gly Tyr Asp Ser His
                 245                 250                 255

 His Phe Val Pro Leu Val Thr Leu Lys Asp Ser Gly Pro Glu Ile
                 260                 265                 270

 Arg Ala Val Pro Leu Val Asn Arg Asp Arg Gly Arg Phe Glu Asp
                 275                 280                 285

 Leu Lys Val His Phe Leu Thr Asp Pro Glu Asn Glu Met Lys Glu
                 290                 295                 300

 Lys Leu Leu Lys Glu Tyr Leu Met Val Ile Glu Ile Pro Val Gln
                 305                 310                 315

 Gly Trp Asp His Gly Thr Thr His Leu Ile Asn Ala Ala Lys Leu
                 320                 325                 330

 Asp Glu Ala Asn Leu Pro Lys Glu Ile Asn Leu Val Asp Asp Tyr
                 335                 340                 345

 Phe Glu Leu Val Gln His Glu Tyr Lys Lys Trp Gln Glu Asn Ser
                 350                 355                 360

 Glu Gln Gly Arg Arg Glu Gly His Ala Gln Asn Pro Met Glu Pro
                 365                 370                 375

 Ser Val Pro Gln Leu Ser Leu Met Asp Val Lys Cys Glu Thr Pro
                 380                 385                 390

 Asn Cys Pro Phe Phe Met Ser Val Asn Thr Gln Pro Leu Cys His
                 395                 400                 405

 Glu Cys Ser Glu Arg Arg Gln Lys Asn Gln Asn Lys Leu Pro Lys
                 410                 415                 420

 Leu Asn Ser Lys Pro Gly Pro Glu Gly Leu Pro Gly Met Ala Leu
                 425                 430                 435

 Gly Ala Ser Arg Gly Glu Ala Tyr Glu Pro Leu Ala Trp Asn Pro
                 440                 445                 450

 Glu Glu Ser Thr Gly Gly Pro His Ser Ala Pro Pro Thr Ala Pro
                 455                 460                 465

 Ser Pro Phe Leu Phe Ser Glu Thr Thr Ala Met Lys Cys Arg Ser
                 470                 475                 480

 Pro Gly Cys Pro Phe Thr Leu Asn Val Gln His Asn Gly Phe Cys
                 485                 490                 495

 Glu Arg Cys His Asn Ala Arg Gln Leu His Ala Ser His Ala Pro
                 500                 505                 510

 Asp His Thr Arg His Leu Asp Pro Gly Lys Cys Gln Ala Cys Leu
                 515                 520                 525

 Gln Asp Val Thr Arg Thr Phe Asn Gly Ile Cys Ser Thr Cys Phe
                 530                 535                 540

 Lys Arg Thr Thr Ala Glu Ala Ser Ser Ser Leu Ser Thr Ser Leu
                 545                 550                 555

 Pro Pro Ser Cys His Gln Arg Ser Lys Ser Asp Pro Ser Arg Leu
                 560                 565                 570

 Val Arg Ser Pro Ser Pro His Ser Cys His Arg Ala Gly Asn Asp
                 575                 580                 585

 Ala Pro Ala Gly Cys Leu Ser Gln Ala Ala Arg Thr Pro Gly Asp
                 590                 595                 600

 Arg Thr Gly Thr Ser Lys Cys Arg Lys Ala Gly Cys Val Tyr Phe
                 605                 610                 615

 Gly Thr Pro Glu Asn Lys Gly Phe Cys Thr Leu Cys Phe Ile Glu
                 620                 625                 630

 Tyr Arg Glu Asn Lys His Phe Ala Ala Ala Ser Gly Lys Val Ser
                 635                 640                 645

 Pro Thr Ala Ser Arg Phe Gln Asn Thr Ile Pro Cys Leu Gly Arg
                 650                 655                 660

 Glu Cys Gly Thr Leu Gly Ser Thr Met Phe Glu Gly Tyr Cys Gln
                 665                 670                 675

 Lys Cys Phe Ile Glu Ala Gln Asn Gln Arg Phe His Glu Ala Lys
                 680                 685                 690

 Arg Thr Glu Glu Gln Leu Arg Ser Ser Gln Arg Arg Asp Val Pro
                 695                 700                 705

 Arg Thr Thr Gln Ser Thr Ser Arg Pro Lys Cys Ala Arg Ala Ser
                 710                 715                 720

 Cys Lys Asn Ile Leu Ala Cys Arg Ser Glu Glu Leu Cys Met Glu
                 725                 730                 735

 Cys Gln His Pro Asn Gln Arg Met Gly Pro Gly Ala His Arg Gly
                 740                 745                 750

 Glu Pro Ala Pro Glu Asp Pro Pro Lys Gln Arg Cys Arg Ala Pro
                 755                 760                 765

 Ala Cys Asp His Phe Gly Asn Ala Lys Cys Asn Gly Tyr Cys Asn
                 770                 775                 780

 Glu Cys Phe Gln Phe Lys Gln Met Tyr Gly
                 785                 790

<210> 663
<211> 4446
<212> DNA
<213> Homo sapien

<400> 663
 tgccttgacc aggacttggg actttgcgaa aggatcgcgg ggcccggaga 50

 ggtgttggag agcacaatgg ctgaacaagt ccttcctcag gctttgtatt 100

 tgagcaatat gcggaaagct gtgaagatac gggagagaac tccagaagac 150

 atttttaaac ctactaatgg gatcattcat cattttaaaa ccatgcaccg 200

 atacacactg gaaatgttca gaacttgcca gttttgtcct cagtttcggg 250

 agatcatcca caaagccctc atcgacagaa acatccaggc caccctggaa 300

 agccagaaga aactcaactg gtgtcgagaa gtccggaagc ttgtggcgct 350

 gaaaacgaac ggtgacggca attgcctcat gcatgccact tctcagtaca 400

 tgtggggcgt tcaggacaca gacttggtac tgaggaaggc gctgttcagc 450

 acgctcaagg aaacagacac acgcaacttt aaattccgct ggcaactgga 500

 gtctctcaaa tctcaggaat ttgttgaaac ggggctttgc tatgatactc 550

 ggaactggaa tgatgaatgg gacaatctta tcaaaatggc ttccacagac 600

 acacccatgg cccgaagtgg acttcagtac aactcactgg aagaaataca 650

 catatttgtc ctttgcaaca tcctcagaag gccaatcatt gtcatttcag 700

 acaaaatgct aagaagtttg gaatcaggtt ccaatttcgc ccctttgaaa 750

 gtgggtggaa tttacttgcc tctccactgg cctgcccagg aatgctacag 800

 ataccccatt gttctcggct atgacagcca tcattttgta cccttggtga 850

 ccctgaagga cagtgggcct gaaatccgag ctgttccact tgttaacaga 900

 gaccggggaa gatttgaaga cttaaaagtt cactttttga cagatcctga 950

 aaatgagatg aaggagaagc tcttaaaaga gtacttaatg gtgatagaaa 1000

 tccccgtcca aggctgggac catggcacaa ctcatctcat caatgccgca 1050

 aagttggatg aagctaactt accaaaagaa atcaatctgg tagatgatta 1100

 ctttgaactt gttcagcatg agtacaagaa atggcaggaa aacagcgagc 1150

 aggggaggag agaggggcac gcccagaatc ccatggaacc ttccgtgccc 1200

 cagctttctc tcatggatgt aaaatgtgaa acgcccaact gccccttctt 1250

 catgtctgtg aacacccagc ctttatgcca tgagtgctca gagaggcggc 1300

 aaaagaatca aaacaaactc ccaaagctga actccaagcc gggccctgag 1350

 gggctccctg gcatggcgct cggggcctct cggggagaag cctatgagcc 1400

 cttggcgtgg aaccctgagg agtccactgg ggggcctcat tcggccccac 1450

 cgacagcacc cagccctttt ctgttcagtg agaccactgc catgaagtgc 1500

 aggagccccg gctgcccctt cacactgaat gtgcagcaca acggattttg 1550

 tgaacgttgc cacaacgccc ggcaacttca cgccagccac gccccagacc 1600

 acacaaggca cttggatccc gggaagtgcc aagcctgcct ccaggatgtt 1650

 accaggacat ttaatgggat ctgcagtact tgcttcaaaa ggactacagc 1700

 agaggcctcc tccagcctca gcaccagcct ccctccttcc tgtcaccagc 1750

 gttccaagtc agatccctcg cggctcgtcc ggagcccctc cccgcattct 1800

 tgccacagag ctggaaacga cgcccctgct ggctgcctgt ctcaagctgc 1850

 acggactcct ggggacagga cggggacgag caagtgcaga aaagccggct 1900

 gcgtgtattt tgggactcca gaaaacaagg gcttttgcac actgtgtttc 1950

 atcgagtaca gagaaaacaa acattttgct gctgcctcag ggaaagtcag 2000

 tcccacagcg tccaggttcc agaacaccat tccgtgcctg gggagggaat 2050

 gcggcaccct tggaagcacc atgtttgaag gatactgcca gaagtgtttc 2100

 attgaagctc agaatcagag atttcatgag gccaaaagga cagaagagca 2150

 actgagatcg agccagcgca gagatgtgcc tcgaaccaca caaagcacct 2200

 caaggcccaa gtgcgcccgg gcctcctgca agaacatcct ggcctgccgc 2250

 agcgaggagc tctgcatgga gtgtcagcat cccaaccaga ggatgggccc 2300

 tggggcccac cggggtgagc ctgcccccga agaccccccc aagcagcgtt 2350

 gccgggcccc cgcctgtgat cattttggca atgccaagtg caacggctac 2400

 tgcaacgaat gctttcagtt caagcagatg tatggctaac cggaaacagg 2450

 tgggtcacct cctgcaagaa gtggggcctc gagctgtcag tcatcatggt 2500

 gctatcctct gaacccctca gctgccactg caacagtggg cttaagggtg 2550

 tctgagcagg agaggaaaga taagctcttc gtggtgccca cgatgctcag 2600

 gtttggtaac ccgggagtgt tcccaggtgg ccttagaaag caaagcttgt 2650

 aactggcaag ggatgatgtc agattcagcc caaggttcct cctctcctac 2700

 caagcaggag gccaggaact tctttggact tggaaggtgt gcggggactg 2750

 gccgaggccc ctgcaccctg cgcatcagga ctgcttcatc gtcttggctg 2800

 agaaagggaa aagacacaca agtcgcgtgg gttggagaag ccagagccat 2850

 tccacctccc ctcccccagc atctctcaga gatgtgaagc cagatcctca 2900

 tggcagcgag gccctctgca agaagctcaa ggaagctcag ggaaaatgga 2950

 cgtattcaga gagtgtttgt agttcatggt ttttccctac ctgcccggtt 3000

 cctttcctga ggacccggca gaaatgcaga accatccatg gactgtgatt 3050

 ctgaggctgc tgagactgaa catgttcaca ttgacagaaa aacaagctgc 3100

 tctttataat atgcaccttt taaaaaatta gaatatttta ctgggaagac 3150

 gtgtaactct ttgggttatt actgtcttta cttctaaaga agttagcttg 3200

 aactgaggag taaaagtgtg tacatatata atataccctt acattatgta 3250

 tgagggattt ttttaaatta tattgaaatg ctgccctaga agtacaatag 3300

 gaaggctaaa taataataac ctgttttctg gttgttgttg gggcatgagc 3350

 ttgtgtatac actgcttgca taaactcaac cagctgcctt tttaaaggga 3400

 gctctagtcc tttttgtgta attcacttta tttattttat tacaaacttc 3450

 aagattattt aagtgaagat atttcttcag ctctggggaa aatgccacag 3500

 tgttctcctg agagaacatc cttgctttga gtcaggctgt gggcaagttc 3550

 ctgaccacag ggagtaaatt ggcctctttg atacactttt gcttgcctcc 3600

 ccaggaaaga aggaattgca tccaaggtat acatacatat tcatcgatgt 3650

 ttcgtgcttc tccttatgaa actccagcta tgtaataaaa aactatactc 3700

 tgtgttctgt taatgcctct gagtgtccta cctccttgga gatgagatag 3750

 ggaaggagca gggatgagac tggcaatggt cacagggaaa gatgtggcct 3800

 tttgtgatgg ttttattttc tgttaacact gtgtcctggg ggggctggga 3850

 agtcccctgc atcccatggt accctggtat tgggacagca aaagccagta 3900

 accatgagta tgaggaaatc tctttctgtt gctggcttac agtttctctg 3950

 tgtgctttgt ggttgctgtc atatttgctc tagaagaaaa aaaaaaaagg 4000

 aggggaaatg cattttcccc agagataaag gctgccattt tgggggtctg 4050

 tacttatggc ctgaaaatat ttgtgatcca taactctaca cagcctttac 4100

 tcatactatt aggcacactt tccccttaga gccccctaag tttttcccag 4150

 acgaatcttt ataatttctt tccaaagata ccaaataaac ttcagtgttt 4200

 tcatctaatt ctcttaaagt tgatatctta atattttgtg ttgatcatta 4250

 tttccattct taatgtgaaa aaaagtaatt atttatactt attataaaaa 4300

 gtatttgaaa tttgcacatt taattgtccc taatagaaag ccacctattc 4350

 tttgttggat ttcttcaagt ttttctaaat aaatgtaact tttcacaaga 4400

 gtcaacatta aaaaataaat tatttaagaa caaaaaaaaa aaaaaa 4446

<210> 664
<211> 790
<212> PRT
<213> Homo sapien

<400> 664
 Met Ala Glu Gln Val Leu Pro Gln Ala Leu Tyr Leu Ser Asn Met
   1               5                  10                  15

 Arg Lys Ala Val Lys Ile Arg Glu Arg Thr Pro Glu Asp Ile Phe
                  20                  25                  30

 Lys Pro Thr Asn Gly Ile Ile His His Phe Lys Thr Met His Arg
                  35                  40                  45

 Tyr Thr Leu Glu Met Phe Arg Thr Cys Gln Phe Cys Pro Gln Phe
                  50                  55                  60

 Arg Glu Ile Ile His Lys Ala Leu Ile Asp Arg Asn Ile Gln Ala
                  65                  70                  75

 Thr Leu Glu Ser Gln Lys Lys Leu Asn Trp Cys Arg Glu Val Arg
                  80                  85                  90

 Lys Leu Val Ala Leu Lys Thr Asn Gly Asp Gly Asn Cys Leu Met
                  95                 100                 105

 His Ala Thr Ser Gln Tyr Met Trp Gly Val Gln Asp Thr Asp Leu
                 110                 115                 120

 Val Leu Arg Lys Ala Leu Phe Ser Thr Leu Lys Glu Thr Asp Thr
                 125                 130                 135

 Arg Asn Phe Lys Phe Arg Trp Gln Leu Glu Ser Leu Lys Ser Gln
                 140                 145                 150

 Glu Phe Val Glu Thr Gly Leu Cys Tyr Asp Thr Arg Asn Trp Asn
                 155                 160                 165

 Asp Glu Trp Asp Asn Leu Ile Lys Met Ala Ser Thr Asp Thr Pro
                 170                 175                 180

 Met Ala Arg Ser Gly Leu Gln Tyr Asn Ser Leu Glu Glu Ile His
                 185                 190                 195

 Ile Phe Val Leu Cys Asn Ile Leu Arg Arg Pro Ile Ile Val Ile
                 200                 205                 210

 Ser Asp Lys Met Leu Arg Ser Leu Glu Ser Gly Ser Asn Phe Ala
                 215                 220                 225

 Pro Leu Lys Val Gly Gly Ile Tyr Leu Pro Leu His Trp Pro Ala
                 230                 235                 240

 Gln Glu Cys Tyr Arg Tyr Pro Ile Val Leu Gly Tyr Asp Ser His
                 245                 250                 255

 His Phe Val Pro Leu Val Thr Leu Lys Asp Ser Gly Pro Glu Ile
                 260                 265                 270

 Arg Ala Val Pro Leu Val Asn Arg Asp Arg Gly Arg Phe Glu Asp
                 275                 280                 285

 Leu Lys Val His Phe Leu Thr Asp Pro Glu Asn Glu Met Lys Glu
                 290                 295                 300

 Lys Leu Leu Lys Glu Tyr Leu Met Val Ile Glu Ile Pro Val Gln
                 305                 310                 315

 Gly Trp Asp His Gly Thr Thr His Leu Ile Asn Ala Ala Lys Leu
                 320                 325                 330

 Asp Glu Ala Asn Leu Pro Lys Glu Ile Asn Leu Val Asp Asp Tyr
                 335                 340                 345

 Phe Glu Leu Val Gln His Glu Tyr Lys Lys Trp Gln Glu Asn Ser
                 350                 355                 360

 Glu Gln Gly Arg Arg Glu Gly His Ala Gln Asn Pro Met Glu Pro
                 365                 370                 375

 Ser Val Pro Gln Leu Ser Leu Met Asp Val Lys Cys Glu Thr Pro
                 380                 385                 390

 Asn Cys Pro Phe Phe Met Ser Val Asn Thr Gln Pro Leu Cys His
                 395                 400                 405

 Glu Cys Ser Glu Arg Arg Gln Lys Asn Gln Asn Lys Leu Pro Lys
                 410                 415                 420

 Leu Asn Ser Lys Pro Gly Pro Glu Gly Leu Pro Gly Met Ala Leu
                 425                 430                 435

 Gly Ala Ser Arg Gly Glu Ala Tyr Glu Pro Leu Ala Trp Asn Pro
                 440                 445                 450

 Glu Glu Ser Thr Gly Gly Pro His Ser Ala Pro Pro Thr Ala Pro
                 455                 460                 465

 Ser Pro Phe Leu Phe Ser Glu Thr Thr Ala Met Lys Cys Arg Ser
                 470                 475                 480

 Pro Gly Cys Pro Phe Thr Leu Asn Val Gln His Asn Gly Phe Cys
                 485                 490                 495

 Glu Arg Cys His Asn Ala Arg Gln Leu His Ala Ser His Ala Pro
                 500                 505                 510

 Asp His Thr Arg His Leu Asp Pro Gly Lys Cys Gln Ala Cys Leu
                 515                 520                 525

 Gln Asp Val Thr Arg Thr Phe Asn Gly Ile Cys Ser Thr Cys Phe
                 530                 535                 540

 Lys Arg Thr Thr Ala Glu Ala Ser Ser Ser Leu Ser Thr Ser Leu
                 545                 550                 555

 Pro Pro Ser Cys His Gln Arg Ser Lys Ser Asp Pro Ser Arg Leu
                 560                 565                 570

 Val Arg Ser Pro Ser Pro His Ser Cys His Arg Ala Gly Asn Asp
                 575                 580                 585

 Ala Pro Ala Gly Cys Leu Ser Gln Ala Ala Arg Thr Pro Gly Asp
                 590                 595                 600

 Arg Thr Gly Thr Ser Lys Cys Arg Lys Ala Gly Cys Val Tyr Phe
                 605                 610                 615

 Gly Thr Pro Glu Asn Lys Gly Phe Cys Thr Leu Cys Phe Ile Glu
                 620                 625                 630

 Tyr Arg Glu Asn Lys His Phe Ala Ala Ala Ser Gly Lys Val Ser
                 635                 640                 645

 Pro Thr Ala Ser Arg Phe Gln Asn Thr Ile Pro Cys Leu Gly Arg
                 650                 655                 660

 Glu Cys Gly Thr Leu Gly Ser Thr Met Phe Glu Gly Tyr Cys Gln
                 665                 670                 675

 Lys Cys Phe Ile Glu Ala Gln Asn Gln Arg Phe His Glu Ala Lys
                 680                 685                 690

 Arg Thr Glu Glu Gln Leu Arg Ser Ser Gln Arg Arg Asp Val Pro
                 695                 700                 705

 Arg Thr Thr Gln Ser Thr Ser Arg Pro Lys Cys Ala Arg Ala Ser
                 710                 715                 720

 Cys Lys Asn Ile Leu Ala Cys Arg Ser Glu Glu Leu Cys Met Glu
                 725                 730                 735

 Cys Gln His Pro Asn Gln Arg Met Gly Pro Gly Ala His Arg Gly
                 740                 745                 750

 Glu Pro Ala Pro Glu Asp Pro Pro Lys Gln Arg Cys Arg Ala Pro
                 755                 760                 765

 Ala Cys Asp His Phe Gly Asn Ala Lys Cys Asn Gly Tyr Cys Asn
                 770                 775                 780

 Glu Cys Phe Gln Phe Lys Gln Met Tyr Gly
                 785                 790

<210> 665
<211> 1103
<212> DNA
<213> Homo sapien

<400> 665
 cttcggtcct gctgtagtgc cttctgcgcc aggcccggtt caatcagcgg 50

 ccacaactgt ctagggctca gacaccacca gccaatgagg gagggcacgt 100

 ggagccgcgt ctgggctcgc ggctcctgac caatggggaa gtggcatgtg 150

 ggagggcgcc ggggttcccc ccgccaatgg ggagctacgg cgcgcggccg 200

 ggacttggag gcggtgcggc gcggcgggtg cggttcagtc ggtcggcggc 250

 ggcagcggag gaggaggagg aggaggagga tgaggaggat gaggaggatg 300

 tgggccacgc aggggctggc ggtgcgcgtg gctctgagcg tgctgccggg 350

 cagccgggcg ctgcggccgg gcgactgcga agtttgtatt tcttatctgg 400

 gaagatttta ccaggacctc aaagacagag atgtcacatt ctcaccagcc 450

 actattgaaa acgaacttat aaagttctgc cgggaagcaa gaggcaaaga 500

 gaatcggttg tgctactata tcggggccac agatgatgca gccaccaaaa 550

 tcatcaatga ggtatcaaag cctctggccc accacatccc tgtggagaag 600

 atctgtgaga agcttaagaa gaaggacagc cagatatgtg agcttaagta 650

 tgacaagcag atcgacctga gcacagtgga cctgaagaag ctccgagtta 700

 aagagctgaa gaagattctg gatgactggg gggagacatg caaaggctgt 750

 gcagaaaagt ctgactacat ccggaagata aatgaactga tgcctaaata 800

 tgcccccaag gcagccagtg caccgaccga tttgtagtct gctcaatctc 850

 tgttgcacct gagggggaaa aaacagttca actgcttact cccaaaacag 900

 cctttttgta atttattttt taagtgggct cctgacaata ctgtatcaga 950

 tgtgaagcct ggagctttcc tgatgatgct ggccctacag tacccccatg 1000

 aggggattcc cttccttctg ttgctggtgt actctaggac ttcaaagtgt 1050

 gtctgggatt tttttattaa agaaaaaaaa tttctagctg tcaaaaaaaa 1100

 aaa 1103

<210> 666
<211> 234
<212> PRT
<213> Homo sapien

<400> 666
 Met Gly Lys Trp His Val Gly Gly Arg Arg Gly Ser Pro Arg Gln
   1               5                  10                  15

 Trp Gly Ala Thr Ala Arg Gly Arg Asp Leu Glu Ala Val Arg Arg
                  20                  25                  30

 Gly Gly Cys Gly Ser Val Gly Arg Arg Arg Gln Arg Arg Arg Arg
                  35                  40                  45

 Arg Arg Arg Arg Met Arg Arg Met Arg Arg Met Trp Ala Thr Gln
                  50                  55                  60

 Gly Leu Ala Val Arg Val Ala Leu Ser Val Leu Pro Gly Ser Arg
                  65                  70                  75

 Ala Leu Arg Pro Gly Asp Cys Glu Val Cys Ile Ser Tyr Leu Gly
                  80                  85                  90

 Arg Phe Tyr Gln Asp Leu Lys Asp Arg Asp Val Thr Phe Ser Pro
                  95                 100                 105

 Ala Thr Ile Glu Asn Glu Leu Ile Lys Phe Cys Arg Glu Ala Arg
                 110                 115                 120

 Gly Lys Glu Asn Arg Leu Cys Tyr Tyr Ile Gly Ala Thr Asp Asp
                 125                 130                 135

 Ala Ala Thr Lys Ile Ile Asn Glu Val Ser Lys Pro Leu Ala His
                 140                 145                 150

 His Ile Pro Val Glu Lys Ile Cys Glu Lys Leu Lys Lys Lys Asp
                 155                 160                 165

 Ser Gln Ile Cys Glu Leu Lys Tyr Asp Lys Gln Ile Asp Leu Ser
                 170                 175                 180

 Thr Val Asp Leu Lys Lys Leu Arg Val Lys Glu Leu Lys Lys Ile
                 185                 190                 195

 Leu Asp Asp Trp Gly Glu Thr Cys Lys Gly Cys Ala Glu Lys Ser
                 200                 205                 210

 Asp Tyr Ile Arg Lys Ile Asn Glu Leu Met Pro Lys Tyr Ala Pro
                 215                 220                 225

 Lys Ala Ala Ser Ala Pro Thr Asp Leu
                 230

<210> 667
<211> 4676
<212> DNA
<213> Homo sapien

<400> 667
 ggggacatgc aacatttaca ggaaactggc tagaagacag caggggaact 50

 cgagaagttg gttgttttca gcagattaaa acaatacaga tttatcagca 100

 agactgttga acgcataacg tgcccaagat gcctgtccct ccccctccag 150

 cacccccgcc gcccccgacg tttgcactgg ccaatacaga gaagcctacc 200

 ttgaataaga cagagcaggc tgggagaaat gctctccttt ctgatatcag 250

 caaagggaag aaactaaaga agacggtcac caatgacaga agtgcaccaa 300

 tactggacaa acctaaagga gctggtgctg gaggcggtgg tggtggcttt 350

 ggtggaggcg gcggatttgg cggaggaggt ggtggcggag gcggtggaag 400

 ttttggaggg ggcggacctc caggtctggg aggattgttc caggctggaa 450

 tgccgaagct gagatccacg gccaacaggg ataatgattc tggaggaagc 500

 cgaccaccat tgttgccacc gggaggaaga tccacatctg cgaaaccctt 550

 ttcaccccca agtggcccag ggaggtttcc tgtgccttct ccaggccaca 600

 gaagtggtcc cccagagcct cagaggaacc gaatgccgcc cccaaggccc 650

 gacgtgggct caaagcctga tagcattcct cctccagtac ctagtactcc 700

 aagacccatt caatcaagtc tgcacaaccg ggggtcccca ccagtgcccg 750

 gaggccccag gcagcccagc cccgggccca ctcctccccc tttccctgga 800

 aaccgcggca ctgctttggg aggaggctca atacgtcagt cccccttgag 850

 ctcctcctcg cccttctcca accggcctcc cctgccgcct acccccagca 900

 gggccttgga tgacaaaccc cctccaccac ctcctccagt gggcaacagg 950

 ccctccatcc acagggaagc ggttccccct cctcctcctc agaacaacaa 1000

 gcctccagtg ccttccactc cgcggccttc ggcctcctca caggccccac 1050

 ctccgccgcc acctcccagc aggcccgggc cgcctcctct gcctccaagt 1100

 tccagcggca atgacgaaac cccaagactc ccacagcgga atctgtccct 1150

 cagttcgtcc acgcccccgt taccttcgcc aggacgttca ggtcctcttc 1200

 ctcccccgcc cagtgagaga cccccacctc cagtgaggga cccgccaggc 1250

 cgatcaggcc ccctcccacc acctcctcca gtaagcagaa acggcagcac 1300

 atctcgggcc ctgcctgcta cccctcagtt gccatccagg agtggagtag 1350

 acagtcccag gagtggaccc aggcctcccc ttcctcctga taggcccagt 1400

 gctggggcac ctcccccacc tccaccatca acatctatta gaaatggctt 1450

 ccaagactct ccatgtgaag atgagtggga aagcagattc tacttccatc 1500

 cgatttccga tttgccacct ccagagccat atgtacaaac gaccaaaagt 1550

 tatcccagca aactggcaag aaacgaaagc cggagtggat ccaaccgaag 1600

 agaaaggggt gctccaccac tccctcccat cccgaggtga tctttgcctg 1650

 ctcttctcta cccaagctca agagctgctt ctgttgctat ctaagaactg 1700

 cataccctcc tccctgcttc ttcccttgtg cctcatgtat gggcaggagg 1750

 aaaggtggga gggggagtgg gaatatgcgt gtgtgggtgg gaatcggtaa 1800

 gaaatgcacc tagcttttca tattgtgttt attctccagg ctattgcttg 1850

 cttcagctgc agcctgcctg tgctggctgc tggggtcgat aggcttttgt 1900

 cgtaataggc agagatgact tgcatcccag ctttccacca accaaattca 1950

 aacattcact gcttatttgt tacagactgt aattattaaa gtccctgaga 2000

 gctgttttct cccgttcctt tttcgcatgc ttggcctcct ctctgtttct 2050

 atgaaccaca gaccacctaa gcaagctgct gagtaagggc tcactggaaa 2100

 cttgcagtca caggatgtcc aatctttggc agtccgagct tggctctagg 2150

 acagagctgt ccaatagaaa tataatgtga gccccatata caatttttac 2200

 atttctaata tattttaaac aagtgaagtt aatatgcatc caaaatattt 2250

 caacctgtaa tcaacataaa attttaatga gatattttat attatttttt 2300

 ggtactgaat cttcaaaatc cagagtgtat tttacactta ccgcacatct 2350

 ccattcagac tagtcacatt tttaagtgct cagtagccag atgtggctgg 2400

 tggctactgg attagacagc acgagtctgg aagatggaag ctagtgcaga 2450

 aacctcttgt ttaaaaaaca aaaaaggcaa gatgggcttg agcgattcaa 2500

 gaggcaacta aaaataaaat taggacccag caccttgttt gacacacagt 2550

 ttgaccttcg attttcctcc cttaacttcc ctcttccctt aatatctgta 2600

 tacaagtgtt gcttcaaagt accaaggtca gaaattgatt cagtacggtt 2650

 tactaaagtc atgtggaata aagccattgg aaacaaatgg aaagcctgtc 2700

 gggacttctg ggctcagaac cagctggctc acgcactcca cttgtcagct 2750

 ggacttctgc cttgtgaaat ggaagcagcc tttgttcctt tctggctgag 2800

 caagctcctg aggctgggag agactaggaa ggcttggtag gaggggaaaa 2850

 aagtcaggaa aagatatcaa atcagaaaca tggaagaaga agggaaccga 2900

 tttgagttgg tgggcaaaac tctaaaaatc taaatctgat gcttatgtaa 2950

 gggttgagcg aattagggag attgctagtg gaaattggag ggaatttgtt 3000

 ttgcatcatt tgtctaggat ctatgcaaat atagctccac taaaggacca 3050

 tagggaagag ccagccttgc cttttcttat atgattttgt ttacaaaatt 3100

 ttactgggac ttttaaatct agctatagag ttgggaaaaa atatttccac 3150

 ttagatattt tacatggttt tgtttaaaat taccattact tgttttttaa 3200

 aaacacatga ccacatatgt atatgtatat ctacctaaac attgtatcat 3250

 ggtttcagta tgttattcat gtattactgg gagatgctac caagaaacca 3300

 acccaaagaa aattctgaaa aatacatttc tatttataga ataaatgttt 3350

 catttatata aaagcaaaag aacttagagt tctaataaat gggatgtcta 3400

 ataaattatg aagttactga tttgaatata ttatattttt ataacttcct 3450

 tgccaaagtc ctgatttagt acattagaga acctgtgttt cctctctcct 3500

 ctaccattca tctctcttcc atacagtcat ttgggctttt tactcaaaga 3550

 gaatcaagaa ataataagat ataacaagct tggcaaagtg ttggcttttt 3600

 aaaaaaaatt tttttaatct ctagcagttt ggtaatttag cagcatcatt 3650

 tatttgggat tcttttatct gatttcaaca gtgaaaaaca tccctatgat 3700

 aaagcctaat gacccatttc acaaaagatg gaatttgccc ttcctagaaa 3750

 atatgacgga gaaaagtctg actcagagaa agtgagtctg aattttataa 3800

 ggggtagtaa gaattggaca attcctttgc atatctgaac ttggcaggta 3850

 ccgttctaaa tctgaaacag ggtgatagct caaagttgcc attcatccag 3900

 aatagattgt tttagaatgt agtgtttaag tgactgtttc attaatacac 3950

 ctacaccctt tctttgaaag tttgcaacct aattgcatct aaaactatga 4000

 ataagttctg tggtaaaatc ttaaactatg gaaaattaca aaaatgaatt 4050

 tttcttccct gaaatcagag cttacatgtg tgttttttta taacattttc 4100

 agataaatgt attcaacatg taatacagta ttttaacatt cacctcttat 4150

 tttatattga aatgtattac agtattaaaa ctcagtgttc agtatttatt 4200

 tcactatgca ttttatttag taaaagccag gagaaatgtt taatccaatg 4250

 gtgccttact ttgtgattta aaagaaatca actttttttt atgtctaagt 4300

 agtagattat ttgcatattt gtaaaaactg ttaggtcttt atattttaaa 4350

 gtgtaatacc agttttgtta ttttagtagc agaaatggga tgattgttaa 4400

 agttccccaa aaatgttggc atgaaattaa tttttccctc cttatagtca 4450

 aggaccgtag aggaagaaaa actttttttt catatcatgc actatgtaaa 4500

 cagacacatt ttgctatctg tgtcatcagg atagtgtaag tggtagggta 4550

 gagactaccc tagacatctg catctttgta agttagccag acaataaaga 4600

 aaagcagaat gaaaaaaaat ctatgtcggt gcggagaaag aggtaatgaa 4650

 atggcaggaa ttcgatatca gcttat 4676

<210> 668
<211> 545
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 36
<223> unknown amino acid

<400> 668
 Gly His Ala Thr Phe Thr Gly Asn Trp Leu Glu Asp Ser Arg Gly
   1               5                  10                  15

 Thr Arg Glu Val Gly Cys Phe Gln Gln Ile Lys Thr Ile Gln Ile
                  20                  25                  30

 Tyr Gln Gln Asp Cys Xaa Thr His Asn Val Pro Lys Met Pro Val
                  35                  40                  45

 Pro Pro Pro Pro Ala Pro Pro Pro Pro Pro Thr Phe Ala Leu Ala
                  50                  55                  60

 Asn Thr Glu Lys Pro Thr Leu Asn Lys Thr Glu Gln Ala Gly Arg
                  65                  70                  75

 Asn Ala Leu Leu Ser Asp Ile Ser Lys Gly Lys Lys Leu Lys Lys
                  80                  85                  90

 Thr Val Thr Asn Asp Arg Ser Ala Pro Ile Leu Asp Lys Pro Lys
                  95                 100                 105

 Gly Ala Gly Ala Gly Gly Gly Gly Gly Gly Phe Gly Gly Gly Gly
                 110                 115                 120

 Gly Phe Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ser Phe Gly
                 125                 130                 135

 Gly Gly Gly Pro Pro Gly Leu Gly Gly Leu Phe Gln Ala Gly Met
                 140                 145                 150

 Pro Lys Leu Arg Ser Thr Ala Asn Arg Asp Asn Asp Ser Gly Gly
                 155                 160                 165

 Ser Arg Pro Pro Leu Leu Pro Pro Gly Gly Arg Ser Thr Ser Ala
                 170                 175                 180

 Lys Pro Phe Ser Pro Pro Ser Gly Pro Gly Arg Phe Pro Val Pro
                 185                 190                 195

 Ser Pro Gly His Arg Ser Gly Pro Pro Glu Pro Gln Arg Asn Arg
                 200                 205                 210

 Met Pro Pro Pro Arg Pro Asp Val Gly Ser Lys Pro Asp Ser Ile
                 215                 220                 225

 Pro Pro Pro Val Pro Ser Thr Pro Arg Pro Ile Gln Ser Ser Leu
                 230                 235                 240

 His Asn Arg Gly Ser Pro Pro Val Pro Gly Gly Pro Arg Gln Pro
                 245                 250                 255

 Ser Pro Gly Pro Thr Pro Pro Pro Phe Pro Gly Asn Arg Gly Thr
                 260                 265                 270

 Ala Leu Gly Gly Gly Ser Ile Arg Gln Ser Pro Leu Ser Ser Ser
                 275                 280                 285

 Ser Pro Phe Ser Asn Arg Pro Pro Leu Pro Pro Thr Pro Ser Arg
                 290                 295                 300

 Ala Leu Asp Asp Lys Pro Pro Pro Pro Pro Pro Pro Val Gly Asn
                 305                 310                 315

 Arg Pro Ser Ile His Arg Glu Ala Val Pro Pro Pro Pro Pro Gln
                 320                 325                 330

 Asn Asn Lys Pro Pro Val Pro Ser Thr Pro Arg Pro Ser Ala Ser
                 335                 340                 345

 Ser Gln Ala Pro Pro Pro Pro Pro Pro Pro Ser Arg Pro Gly Pro
                 350                 355                 360

 Pro Pro Leu Pro Pro Ser Ser Ser Gly Asn Asp Glu Thr Pro Arg
                 365                 370                 375

 Leu Pro Gln Arg Asn Leu Ser Leu Ser Ser Ser Thr Pro Pro Leu
                 380                 385                 390

 Pro Ser Pro Gly Arg Ser Gly Pro Leu Pro Pro Pro Pro Ser Glu
                 395                 400                 405

 Arg Pro Pro Pro Pro Val Arg Asp Pro Pro Gly Arg Ser Gly Pro
                 410                 415                 420

 Leu Pro Pro Pro Pro Pro Val Ser Arg Asn Gly Ser Thr Ser Arg
                 425                 430                 435

 Ala Leu Pro Ala Thr Pro Gln Leu Pro Ser Arg Ser Gly Val Asp
                 440                 445                 450

 Ser Pro Arg Ser Gly Pro Arg Pro Pro Leu Pro Pro Asp Arg Pro
                 455                 460                 465

 Ser Ala Gly Ala Pro Pro Pro Pro Pro Pro Ser Thr Ser Ile Arg
                 470                 475                 480

 Asn Gly Phe Gln Asp Ser Pro Cys Glu Asp Glu Trp Glu Ser Arg
                 485                 490                 495

 Phe Tyr Phe His Pro Ile Ser Asp Leu Pro Pro Pro Glu Pro Tyr
                 500                 505                 510

 Val Gln Thr Thr Lys Ser Tyr Pro Ser Lys Leu Ala Arg Asn Glu
                 515                 520                 525

 Ser Arg Ser Gly Ser Asn Arg Arg Glu Arg Gly Ala Pro Pro Leu
                 530                 535                 540

 Pro Pro Ile Pro Arg
                 545

<210> 669
<211> 1914
<212> DNA
<213> Homo sapien

<400> 669
 gcagccaggc gcgcactgca cagctctctt ctctcgccgc cgcccgagcg 50

 cacccttcag cccgcgcgcc ggccgtgagt cctcggtgct cgcccgccgg 100

 ccagacaaac agcccgcccg accccgtccc gaccctggcc gccccgagcg 150

 gagcctggag caaaatgatg cttcaacacc caggccaggt ctctgcctcg 200

 gaagtgagtg cttctgccat cgtcccctgc ctgtcccctc ctgggtcact 250

 ggtgtttgag gattttgcta acctgacgcc ctttgtcaag gaagagctga 300

 ggtttgccat ccagaacaag cacctctgcc accggatgtc ctctgcgctg 350

 gaatcagtca ctgtcagcga cagacccctc ggggtgtcca tcacaaaagc 400

 cgaggtagcc cctgaagaag atgaaaggaa aaagaggcga cgagaaagaa 450

 ataagattgc agctgcaaag tgccgaaaca agaagaagga gaagacggag 500

 tgcctgcaga aagagtcgga gaagctggaa agtgtgaatg ctgaactgaa 550

 ggctcagatt gaggagctca agaacgagaa gcagcatttg atatacatgc 600

 tcaaccttca tcggcccacg tgtattgtcc gggctcagaa tgggaggact 650

 ccagaagatg agagaaacct ctttatccaa cagataaaag aaggaacatt 700

 gcagagctaa gcagtcgtgg tatgggggcg actggggagt cctcattgaa 750

 tcctcatttt atacccaaaa ccctgaagcc attggagagc tgtcttcctg 800

 tgtacctcta gaatcccagc agcagagaac catcaaggcg ggagggcctg 850

 cagtgattca gcaggccctt cccattctgc cccagagtgg gtcttggacc 900

 agggcaagtg catctttgcc tcaactccag gatttaggcc ttaacacact 950

 ggccattctt atgttccaga tggcccccag ctggtgtcct gcccgccttt 1000

 catctggatt ctacaaaaaa ccaggatgcc caccgttaga ttcaggcagc 1050

 agtgtctgta cctcgggtgg gagggatggg gccatctcct tcaccgtggc 1100

 taccattgtc actcgtaggg gatgtggagt gagaacagca tttagtgaag 1150

 ttgtgcaacg gccagggttg tgctttctag caaatatgct gttatgtcca 1200

 gaaattgtgt gtgcaagaaa actaggcaat gtactcttcc gatgtttgtg 1250

 tcacacaaca ctgatgtgac ttttatatgc tttttctcag atctggtttc 1300

 taagagtttt ggggggcggg gctgtcacca cgtgcagtat ctcaagatat 1350

 tcaggtggcc agaagagctt gtcagcaaga ggaggaacag aattctccca 1400

 gcgttaacac aaaatccatg ggcagcatga tggcaggtcc tctgttgcaa 1450

 actcagttcc aaagtcacag gaagaaagca gaaagttcaa cttccaaagg 1500

 gttaggactc tccactcaat gtcttaggtc aggagttgtg tctaggctgg 1550

 aagagccaaa gaaatattcc attttccttt ccttgtggtt gaaaccacag 1600

 tcagtggaga gatgtttgga acacagtcag tggagctggt ggtaccaggt 1650

 ttagcattat tggatgtcaa aagcattttt tttgtcatgt agctgtttta 1700

 agaaatctgg cccagggtgt ttgcagctgt gagaagtcac tcacactggc 1750

 cacaaggacg ctggctactg tctattaaaa ttctgatgtt tctgtgaaat 1800

 tctcagagtg tttaattgta ctcaatggta tcattacaat tttctgtaag 1850

 agaaaatatt acttatttat cctagtattc ctaacctgtc agaataataa 1900

 atattgtggt aaaa 1914

<210> 670
<211> 181
<212> PRT
<213> Homo sapien

<400> 670
 Met Met Leu Gln His Pro Gly Gln Val Ser Ala Ser Glu Val Ser
   1               5                  10                  15

 Ala Ser Ala Ile Val Pro Cys Leu Ser Pro Pro Gly Ser Leu Val
                  20                  25                  30

 Phe Glu Asp Phe Ala Asn Leu Thr Pro Phe Val Lys Glu Glu Leu
                  35                  40                  45

 Arg Phe Ala Ile Gln Asn Lys His Leu Cys His Arg Met Ser Ser
                  50                  55                  60

 Ala Leu Glu Ser Val Thr Val Ser Asp Arg Pro Leu Gly Val Ser
                  65                  70                  75

 Ile Thr Lys Ala Glu Val Ala Pro Glu Glu Asp Glu Arg Lys Lys
                  80                  85                  90

 Arg Arg Arg Glu Arg Asn Lys Ile Ala Ala Ala Lys Cys Arg Asn
                  95                 100                 105

 Lys Lys Lys Glu Lys Thr Glu Cys Leu Gln Lys Glu Ser Glu Lys
                 110                 115                 120

 Leu Glu Ser Val Asn Ala Glu Leu Lys Ala Gln Ile Glu Glu Leu
                 125                 130                 135

 Lys Asn Glu Lys Gln His Leu Ile Tyr Met Leu Asn Leu His Arg
                 140                 145                 150

 Pro Thr Cys Ile Val Arg Ala Gln Asn Gly Arg Thr Pro Glu Asp
                 155                 160                 165

 Glu Arg Asn Leu Phe Ile Gln Gln Ile Lys Glu Gly Thr Leu Gln
                 170                 175                 180

 Ser


<210> 671
<211> 736
<212> DNA
<213> Homo sapien

<400> 671
 cgagctggag aggtggtcgg agaagtagga acctcctgcc gggctcgtgg 50

 cggcttctgt ccgctccgcg gagggaagcg ccttccccac aggacatcaa 100

 tgcaagcttg aataagaaaa acaaattctt cctcctaagc catggcatat 150

 cagttataca gaaatactac tttgggaaac agtcttcagg agagcctaga 200

 tgagctcata cagtctcaac agatcacccc ccaacttgcc cttcaagttc 250

 tacttcagtt tgataaggct ataaatgcag cactggctca gagggtcagg 300

 aacagagtca atttcagggg ctctctaaat acgtacagat tctgcgataa 350

 tgtgtggact tttgtactga atgatgttga attcagagag gtgacagaac 400

 ttattaaagt ggataaagtg aaaattgtag cctgtgatgg taaaaatact 450

 ggctccaata ctacagaatg aatagaaaaa atatgacttt tttacaccat 500

 cttctgttat tcattgcttt tgaagagaag catagaagag actttttatt 550

 tattctagaa ttgcagaaat gactacactg tgctatacca gagaattcca 600

 gtagaaagaa acttgtaact ctgtagcctc ttacatcacc tttattatac 650

 agcatgaaaa accataactt ttttttaagg acaaaagttg ttgccttcct 700

 aagaaccttc tttaataaac tcattttaaa actctg 736

<210> 672
<211> 109
<212> PRT
<213> Homo sapien

<400> 672
 Met Ala Tyr Gln Leu Tyr Arg Asn Thr Thr Leu Gly Asn Ser Leu
   1               5                  10                  15

 Gln Glu Ser Leu Asp Glu Leu Ile Gln Ser Gln Gln Ile Thr Pro
                  20                  25                  30

 Gln Leu Ala Leu Gln Val Leu Leu Gln Phe Asp Lys Ala Ile Asn
                  35                  40                  45

 Ala Ala Leu Ala Gln Arg Val Arg Asn Arg Val Asn Phe Arg Gly
                  50                  55                  60

 Ser Leu Asn Thr Tyr Arg Phe Cys Asp Asn Val Trp Thr Phe Val
                  65                  70                  75

 Leu Asn Asp Val Glu Phe Arg Glu Val Thr Glu Leu Ile Lys Val
                  80                  85                  90

 Asp Lys Val Lys Ile Val Ala Cys Asp Gly Lys Asn Thr Gly Ser
                  95                 100                 105

 Asn Thr Thr Glu


<210> 673
<211> 1776
<212> DNA
<213> Homo sapien

<400> 673
 tttcatttcc tcactgacta taaaagaata gagaaggaag ggcttcagtg 50

 accggctgcc tggctgactt acagcagtca gactctgaca ggatcatggc 100

 tatgatggag gtccaggggg gacccagcct gggacagacc tgcgtgctga 150

 tcgtgatctt cacagtgctc ctgcagtctc tctgtgtggc tgtaacttac 200

 gtgtacttta ccaacgagct gaagcagatg caggacaagt actccaaaag 250

 tggcattgct tgtttcttaa aagaagatga cagttattgg gaccccaatg 300

 acgaagagag tatgaacagc ccctgctggc aagtcaagtg gcaactccgt 350

 cagctcgtta gaaagatgat tttgagaacc tctgaggaaa ccatttctac 400

 agttcaagaa aagcaacaaa atatttctcc cctagtgaga gaaagaggtc 450

 ctcagagagt agcagctcac ataactggga ccagaggaag aagcaacaca 500

 ttgtcttctc caaactccaa gaatgaaaag gctctgggcc gcaaaataaa 550

 ctcctgggaa tcatcaagga gtgggcattc attcctgagc aacttgcact 600

 tgaggaatgg tgaactggtc atccatgaaa aagggtttta ctacatctat 650

 tcccaaacat actttcgatt tcaggaggaa ataaaagaaa acacaaagaa 700

 cgacaaacaa atggtccaat atatttacaa atacacaagt tatcctgacc 750

 ctatattgtt gatgaaaagt gctagaaata gttgttggtc taaagatgca 800

 gaatatggac tctattccat ctatcaaggg ggaatatttg agcttaagga 850

 aaatgacaga atttttgttt ctgtaacaaa tgagcacttg atagacatgg 900

 accatgaagc cagttttttc ggggcctttt tagttggcta actgacctgg 950

 aaagaaaaag caataacctc aaagtgacta ttcagttttc aggatgatac 1000

 actatgaaga tgtttcaaaa aatctgacca aaacaaacaa acagaaaaca 1050

 gaaaacaaaa aaacctctat gcaatctgag tagagcagcc acaaccaaaa 1100

 aattctacaa cacacactgt tctgaaagtg actcacttat cccaagagaa 1150

 tgaaattgct gaaagatctt tcaggactct acctcatatc agtttgctag 1200

 cagaaatcta gaagactgtc agcttccaaa cattaatgca atggttaaca 1250

 tcttctgtct ttataatcta ctccttgtaa agactgtaga agaaagagca 1300

 acaatccatc tctcaagtag tgtatcacag tagtagcctc caggtttcct 1350

 taagggacaa catccttaag tcaaaagaga gaagaggcac cactaaaaga 1400

 tcgcagtttg cctggtgcag tggctcacac ctgtaatccc aacattttgg 1450

 gaacccaagg tgggtagatc acgagatcaa gagatcaaga ccatagtgac 1500

 caacatagtg aaaccccatc tctactgaaa gtacaaaaat tagctgggtg 1550

 tgttggcaca tgcctgtagt cccagctact tgagaggctg aggcaagaga 1600

 attgtttgaa cccgggaggc agaggttgca gtgtggtgag atcatgccac 1650

 tacactccag cctggcgaca gagcgagact tggtttcaaa aaaaaaaaaa 1700

 aaaaaaactt cagtaagtac gtgttatttt tttcaataaa attctattac 1750

 agtatgtcaa aaaaaaaaaa aaaaaa 1776

<210> 674
<211> 281
<212> PRT
<213> Homo sapien

<400> 674
 Met Ala Met Met Glu Val Gln Gly Gly Pro Ser Leu Gly Gln Thr
   1               5                  10                  15

 Cys Val Leu Ile Val Ile Phe Thr Val Leu Leu Gln Ser Leu Cys
                  20                  25                  30

 Val Ala Val Thr Tyr Val Tyr Phe Thr Asn Glu Leu Lys Gln Met
                  35                  40                  45

 Gln Asp Lys Tyr Ser Lys Ser Gly Ile Ala Cys Phe Leu Lys Glu
                  50                  55                  60

 Asp Asp Ser Tyr Trp Asp Pro Asn Asp Glu Glu Ser Met Asn Ser
                  65                  70                  75

 Pro Cys Trp Gln Val Lys Trp Gln Leu Arg Gln Leu Val Arg Lys
                  80                  85                  90

 Met Ile Leu Arg Thr Ser Glu Glu Thr Ile Ser Thr Val Gln Glu
                  95                 100                 105

 Lys Gln Gln Asn Ile Ser Pro Leu Val Arg Glu Arg Gly Pro Gln
                 110                 115                 120

 Arg Val Ala Ala His Ile Thr Gly Thr Arg Gly Arg Ser Asn Thr
                 125                 130                 135

 Leu Ser Ser Pro Asn Ser Lys Asn Glu Lys Ala Leu Gly Arg Lys
                 140                 145                 150

 Ile Asn Ser Trp Glu Ser Ser Arg Ser Gly His Ser Phe Leu Ser
                 155                 160                 165

 Asn Leu His Leu Arg Asn Gly Glu Leu Val Ile His Glu Lys Gly
                 170                 175                 180

 Phe Tyr Tyr Ile Tyr Ser Gln Thr Tyr Phe Arg Phe Gln Glu Glu
                 185                 190                 195

 Ile Lys Glu Asn Thr Lys Asn Asp Lys Gln Met Val Gln Tyr Ile
                 200                 205                 210

 Tyr Lys Tyr Thr Ser Tyr Pro Asp Pro Ile Leu Leu Met Lys Ser
                 215                 220                 225

 Ala Arg Asn Ser Cys Trp Ser Lys Asp Ala Glu Tyr Gly Leu Tyr
                 230                 235                 240

 Ser Ile Tyr Gln Gly Gly Ile Phe Glu Leu Lys Glu Asn Asp Arg
                 245                 250                 255

 Ile Phe Val Ser Val Thr Asn Glu His Leu Ile Asp Met Asp His
                 260                 265                 270

 Glu Ala Ser Phe Phe Gly Ala Phe Leu Val Gly
                 275                 280

<210> 675
<211> 1776
<212> DNA
<213> Homo sapien

<400> 675
 tttcatttcc tcactgacta taaaagaata gagaaggaag ggcttcagtg 50

 accggctgcc tggctgactt acagcagtca gactctgaca ggatcatggc 100

 tatgatggag gtccaggggg gacccagcct gggacagacc tgcgtgctga 150

 tcgtgatctt cacagtgctc ctgcagtctc tctgtgtggc tgtaacttac 200

 gtgtacttta ccaacgagct gaagcagatg caggacaagt actccaaaag 250

 tggcattgct tgtttcttaa aagaagatga cagttattgg gaccccaatg 300

 acgaagagag tatgaacagc ccctgctggc aagtcaagtg gcaactccgt 350

 cagctcgtta gaaagatgat tttgagaacc tctgaggaaa ccatttctac 400

 agttcaagaa aagcaacaaa atatttctcc cctagtgaga gaaagaggtc 450

 ctcagagagt agcagctcac ataactggga ccagaggaag aagcaacaca 500

 ttgtcttctc caaactccaa gaatgaaaag gctctgggcc gcaaaataaa 550

 ctcctgggaa tcatcaagga gtgggcattc attcctgagc aacttgcact 600

 tgaggaatgg tgaactggtc atccatgaaa aagggtttta ctacatctat 650

 tcccaaacat actttcgatt tcaggaggaa ataaaagaaa acacaaagaa 700

 cgacaaacaa atggtccaat atatttacaa atacacaagt tatcctgacc 750

 ctatattgtt gatgaaaagt gctagaaata gttgttggtc taaagatgca 800

 gaatatggac tctattccat ctatcaaggg ggaatatttg agcttaagga 850

 aaatgacaga atttttgttt ctgtaacaaa tgagcacttg atagacatgg 900

 accatgaagc cagttttttc ggggcctttt tagttggcta actgacctgg 950

 aaagaaaaag caataacctc aaagtgacta ttcagttttc aggatgatac 1000

 actatgaaga tgtttcaaaa aatctgacca aaacaaacaa acagaaaaca 1050

 gaaaacaaaa aaacctctat gcaatctgag tagagcagcc acaaccaaaa 1100

 aattctacaa cacacactgt tctgaaagtg actcacttat cccaagagaa 1150

 tgaaattgct gaaagatctt tcaggactct acctcatatc agtttgctag 1200

 cagaaatcta gaagactgtc agcttccaaa cattaatgca atggttaaca 1250

 tcttctgtct ttataatcta ctccttgtaa agactgtaga agaaagagca 1300

 acaatccatc tctcaagtag tgtatcacag tagtagcctc caggtttcct 1350

 taagggacaa catccttaag tcaaaagaga gaagaggcac cactaaaaga 1400

 tcgcagtttg cctggtgcag tggctcacac ctgtaatccc aacattttgg 1450

 gaacccaagg tgggtagatc acgagatcaa gagatcaaga ccatagtgac 1500

 caacatagtg aaaccccatc tctactgaaa gtacaaaaat tagctgggtg 1550

 tgttggcaca tgcctgtagt cccagctact tgagaggctg aggcaagaga 1600

 attgtttgaa cccgggaggc agaggttgca gtgtggtgag atcatgccac 1650

 tacactccag cctggcgaca gagcgagact tggtttcaaa aaaaaaaaaa 1700

 aaaaaaactt cagtaagtac gtgttatttt tttcaataaa attctattac 1750

 agtatgtcaa aaaaaaaaaa aaaaaa 1776

<210> 676
<211> 281
<212> PRT
<213> Homo sapien

<400> 676
 Met Ala Met Met Glu Val Gln Gly Gly Pro Ser Leu Gly Gln Thr
   1               5                  10                  15

 Cys Val Leu Ile Val Ile Phe Thr Val Leu Leu Gln Ser Leu Cys
                  20                  25                  30

 Val Ala Val Thr Tyr Val Tyr Phe Thr Asn Glu Leu Lys Gln Met
                  35                  40                  45

 Gln Asp Lys Tyr Ser Lys Ser Gly Ile Ala Cys Phe Leu Lys Glu
                  50                  55                  60

 Asp Asp Ser Tyr Trp Asp Pro Asn Asp Glu Glu Ser Met Asn Ser
                  65                  70                  75

 Pro Cys Trp Gln Val Lys Trp Gln Leu Arg Gln Leu Val Arg Lys
                  80                  85                  90

 Met Ile Leu Arg Thr Ser Glu Glu Thr Ile Ser Thr Val Gln Glu
                  95                 100                 105

 Lys Gln Gln Asn Ile Ser Pro Leu Val Arg Glu Arg Gly Pro Gln
                 110                 115                 120

 Arg Val Ala Ala His Ile Thr Gly Thr Arg Gly Arg Ser Asn Thr
                 125                 130                 135

 Leu Ser Ser Pro Asn Ser Lys Asn Glu Lys Ala Leu Gly Arg Lys
                 140                 145                 150

 Ile Asn Ser Trp Glu Ser Ser Arg Ser Gly His Ser Phe Leu Ser
                 155                 160                 165

 Asn Leu His Leu Arg Asn Gly Glu Leu Val Ile His Glu Lys Gly
                 170                 175                 180

 Phe Tyr Tyr Ile Tyr Ser Gln Thr Tyr Phe Arg Phe Gln Glu Glu
                 185                 190                 195

 Ile Lys Glu Asn Thr Lys Asn Asp Lys Gln Met Val Gln Tyr Ile
                 200                 205                 210

 Tyr Lys Tyr Thr Ser Tyr Pro Asp Pro Ile Leu Leu Met Lys Ser
                 215                 220                 225

 Ala Arg Asn Ser Cys Trp Ser Lys Asp Ala Glu Tyr Gly Leu Tyr
                 230                 235                 240

 Ser Ile Tyr Gln Gly Gly Ile Phe Glu Leu Lys Glu Asn Asp Arg
                 245                 250                 255

 Ile Phe Val Ser Val Thr Asn Glu His Leu Ile Asp Met Asp His
                 260                 265                 270

 Glu Ala Ser Phe Phe Gly Ala Phe Leu Val Gly
                 275                 280

<210> 677
<211> 1614
<212> DNA
<213> Mus musculus

<400> 677
 agtgctccgc gcgctcttga cgtccggagc ccctggagta ggcgcttccg 50

 gccattcata ctgcagtcgg tcagtgttcg gttgaaggat tctgtgtgct 100

 gtcggaccca gagggtgacg gcgccgctag gatgaagctc gtgagatttt 150

 tgatgaaatt gagtcatgaa actgtaacca ttgaattgaa gaacggaaca 200

 caggtccatg gaacaatcac aggtgtggat gtcagcatga atacacatct 250

 taaagctgtg aaaatgaccc tgaagaacag agaacctgta cagctggaaa 300

 cgctgagtat tcgaggaaat aacattcggt attttattct accagacagt 350

 ttacctctgg atacactact tgtggatgtt gaacctaagg tgaaatctaa 400

 gaaaagggaa gctgttgcag gaagaggcag aggaagagga agaggaagag 450

 gacgtggccg tggcagagga agagggggtc ctaggcgata atgtctctca 500

 agatttcaaa gtcatatgag atttgggata ttttttgtac aggttgtgtt 550

 tgtttatgtc agtttttaat aaacataaat gtgggacaga gctgtctatt 600

 tagtatatca aagttttagt agtttcctcc acattcacga aattaccaca 650

 gtgagagcta agcatttcta ctgggcagtt tcatttttag ttgatcaggt 700

 tttaagtttt tgaactaaaa tttttctttt tctttttatg atgaataagg 750

 ttaaaataaa agccttagac aaattaaatt tggcagagtt taattgagca 800

 aaggacaatt cacaaatcag gtagcccctg aaccataata ggctcagagg 850

 cttcagccca gctgcatagt tgaagattta tggacagaag gaaagtgatg 900

 tatggaaaat ggaagtgaga tacagcaaca gccggattag ttacagttca 950

 gcgtttgcct tatttgaata tggtttgaac agttcgctgt ctttggttgg 1000

 ctgaaactta gtgattgcca caagagtagg gtaccgtctg tttacacgtc 1050

 cagttaggct acagttctat gtactgagaa acctttaagc tgaacttgag 1100

 atatgtaaag agactttagg ctaaacttaa caatatatat aggatatata 1150

 cccttctact tcacatgcac tgaatatgca ttttattgct ttactcttca 1200

 ttctgtggca cctacccaca ggggaagtaa gaagtttgtt ttggtatttc 1250

 ggaaactaaa gtccttatgg gatggggtct agaattgatt ctcctttcct 1300

 gagttttact ccacggagtc ttaggtacct ggtaaaaagt tgtcttctaa 1350

 attaagggtc attgctttgt tgtctagctg ctaatgtctt acttttgttt 1400

 cttttgcttt ttaatcagtt cttaatagga tatagtttta tgttttccaa 1450

 gttataactt ggagttaatg gtcactagat tatcagttat gagcagtgtt 1500

 aaaatctcct attaatgtgt aatgtacctg tcagtgcctc ctttattaag 1550

 gggttctttg agaataaaag agaaaagacc tactttattt gacagcaaaa 1600

 aaaaaaagga attc 1614

<210> 678
<211> 119
<212> PRT
<213> Mus musculus

<400> 678
 Met Lys Leu Val Arg Phe Leu Met Lys Leu Ser His Glu Thr Val
   1               5                  10                  15

 Thr Ile Glu Leu Lys Asn Gly Thr Gln Val His Gly Thr Ile Thr
                  20                  25                  30

 Gly Val Asp Val Ser Met Asn Thr His Leu Lys Ala Val Lys Met
                  35                  40                  45

 Thr Leu Lys Asn Arg Glu Pro Val Gln Leu Glu Thr Leu Ser Ile
                  50                  55                  60

 Arg Gly Asn Asn Ile Arg Tyr Phe Ile Leu Pro Asp Ser Leu Pro
                  65                  70                  75

 Leu Asp Thr Leu Leu Val Asp Val Glu Pro Lys Val Lys Ser Lys
                  80                  85                  90

 Lys Arg Glu Ala Val Ala Gly Arg Gly Arg Gly Arg Gly Arg Gly
                  95                 100                 105

 Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Gly Pro Arg Arg
                 110                 115

<210> 679
<211> 4074
<212> DNA
<213> Homo sapien

<400> 679
 cacgccccgc gctgctgggt cccgccagac acgccgccgc cgcaggaaag 50

 tctacagttt ggtaccccag gactcgctgg tcaggaaagc cctgcaggac 100

 atgagtgtta ggcccgacgc ctggcccttg gcagcttggg aggtggctgg 150

 ggctgctttt gcctttgcca gagacagctc caactgagga cctctccaac 200

 gggcccatcc acagtccttc cttcccctag tgtctgggaa gacaggcgcg 250

 atgatggact ccccgttcct ggagctgtgg cagtccaagg cagtgtccat 300

 cagggagcag ctgggactcg gggaccggcc caacgactcc tattgctaca 350

 actcggccaa aaacagcacc gtgctccagg gggtcacctt tggtggcatc 400

 cccactgtcc tgctcataga cgtcagctgc ttcctgttct taatcttggt 450

 gttttctatt ataagaagaa gattctggga ctatggccgc attgccctgg 500

 tgtcagaagc agacagcgag tccagatttc agagattgtc atcgacttcc 550

 tcctcaggtc aacaagactt tgaaaatgag ctgggatgct gtccctggct 600

 gactgccatc ttccgtctgc atgatgacca gatcctggaa tggtgtgggg 650

 aggacgccat ccactacctg tccttccaga ggcacatcat cttcctgttg 700

 gtggtggtca gctttttgtc cctgtgtgtc atcctgcctg tcaacctctc 750

 aggggatttg ctggacaaag acccgtatag ttttgggagg acaacaatag 800

 caaacctaca gactgacaat gacctccttt ggctgcacac catctttgct 850

 gtcatttacc tcttcttcac tgtgggtttc atgcggcacc acactcagtc 900

 cattaagtac aaagaggaga acctggtgag gcggaccctg ttcatcacag 950

 gactccccag agatgccagg aaggagactg tggagagcca cttccgggac 1000

 gcgtatccca cgtgtgaggt ggttgatgtg cagctgtgct acaacgtggc 1050

 caaactgatc tacctgtgca aggagaaaaa gaagactgag aagagcctga 1100

 cctattacac aaacctgcag gtgaagacag gccagcggac cctcatcaac 1150

 cccaagccct gtggccagtt ttgctgctgt gaagtgctgg gctgtgagtg 1200

 ggaagacgcc atctcttact acacacggat gaaggacagg ctgctggaga 1250

 ggatcacaga ggaagaacgc cacgtccagg accagcccct gggaatggcc 1300

 ttcgtcacct tccaggagaa gtccatggcc acctacatcc tgaaagattt 1350

 caatgcctgc aagtgtcaga gccttcagtg caaaggtgag ccccagccgt 1400

 cctcccatag cagggagctc tatacctcca agtggacagt cacctttgct 1450

 gctgaccctg aggacatctg ctggaagaac ctctctatcc agggcctccg 1500

 ctggtggcta cagtggctgg gcatcaactt caccctcttc ctggggctat 1550

 ttttcctgac cacaccctcc atcatcctgt ccaccatgga caagtttaat 1600

 gtcaccaaac ccatccatgc gctgaataac ccgatcatca gccagttctt 1650

 ccccaccctc ctgctctggt ccttctcggc cctgctcccc tccattgtct 1700

 actactctac actgctggag tctcactgga ccaagtcggg ggaaaaccag 1750

 atcatgatga ccaaagtcta catattcttg atcttcatgg tgctgatcct 1800

 gccctccctg ggtctcacca gtctagattt tttcttccgg tggctctttg 1850

 acaaaacttc ctcggaggcc tccatcaggt tggagtgcgt cttcctgcct 1900

 gaccagggtg ccttctttgt gaactatgtc atcgcctcgg ccttcatcgg 1950

 caatggcatg gagctgctgc ggctgccagg tctcatcctc tataccttcc 2000

 gcatgatcat ggccaagacg gctgctgacc gcaggaatgt caagcagaac 2050

 caggccttcc agtacgagtt tggagccatg tatgcatgga tgctgtgtgt 2100

 cttcactgtc atcgtggcct acagcatcac ttgtcccatc atcgcgccat 2150

 ttggcctcat ctacatcctg ctcaagcaca tggtggaccg gcacaacctc 2200

 tacttcgtct acctcccagc caagctggag aaggggatcc actttgccgc 2250

 tgtgaaccag gccttggcag cccccatcct gtgcctcttc tggctctact 2300

 tcttttcctt cctgcgcctg ggtatgaagg cccccgccac tctgttcacc 2350

 ttcctggtgc tgctgctcac catcctggtc tgcctggctc acacctgctt 2400

 tggatgcttc aagcacctca gccctctgaa ctacaaaaca gaagagcctg 2450

 caagtgacaa aggaagtgag gcagaggccc acatgccccc accgttcaca 2500

 ccctacgtgc ctcggattct gaacggcttg gcctcggaga ggacagcact 2550

 gtctccgcag cagcagcagc agcagaccta tggtgccatc cacaacatca 2600

 gcgggactat ccctggacag tgcttggcgc agagcgccac gggcagtgtg 2650

 gctgctgccc cccaggaggc ctgaggctgg gtctcactgc tctgaaaaga 2700

 cacaaccaga atggcctggg gctcaggccc ttggctgagt gggaatgcgt 2750

 tgggactgcc cagctgagct atcaggtgcc catcttttct ggtcccagca 2800

 gtggtgagga gagcacaggc aggcctcgcc cctcccttgc tcacccagtt 2850

 tcccctccgg cacaagcttc cagctctgca gctggggtga catccccagt 2900

 ggtttgtcgc caagaccatg tggtggactt ttcgcccccc aaactgatga 2950

 gtccgggaga atatatggag agagagatgt aacaagggga aggcctcctc 3000

 ccttctgagc acacacacaa ccgataacca aagagatgct gcagtccagg 3050

 tctgaggtcc cgctggcatc cagctccctg ctccatggcc agtccctccc 3100

 cagcccagca gtccctccag gctacatcca ggagtaagct atggggaaca 3150

 ggttgggagg tggccagtgc tcctgccagc tgtgcacaca tctctgtatc 3200

 ccgctagagt tctgtgtttt tgtatcatgt tgtcagggac gctagctggg 3250

 tcagggttac cccatagcag gcagggacaa ggaccactca taatatgccc 3300

 attggaccac agttaagatc cagcctctct cacctcttca gggctgagtg 3350

 catgagtctg cacctccagg caggctctgt gcagtactca ccccctccgt 3400

 ctgctccctc caaggtgtgg gggtgggcag tgctcagggc ctcctcggag 3450

 ccaaaggaca gcatggtcgg cacagaggaa ggggtacctg ggctgggtgc 3500

 agggccatcc cactgccctt gagctgtggc tctggcagga aggaggggca 3550

 gcccatccct cttctccctc ctggggattc tggggaatgg gatgcaactt 3600

 aagacttctg cctgagaagc ctcctccctg ctgcctccag ggggcaccaa 3650

 ggcacaagcc tgtgcagtag gggcgggatg ggggtgtgga agagcaggtc 3700

 caggctccta gcacaactgg cctggggcct tggcacctct gtaggccctg 3750

 cctgtgcctg tccgctggcc tggggggcct gggcttatct gggccttctc 3800

 actcagggac tctcttgacg ctgacttgcc cccgcagcgg tggccagtgc 3850

 tgcctctgct ccaagctgcc cctgcgctgg gaggggtggg ggcggtgcca 3900

 ttggtctggt gcagcatagc cctggccagt ggcctcatcc ccagcaggcc 3950

 tcccgtgcct ctgccagcaa ggaggggccg gccagctctg cttgcacagg 4000

 gggccccatg tggggtcagc gcacgctcat gtcactgagt tccagccgct 4050

 tttagagtaa agtcgtttat catc 4074

<210> 680
<211> 807
<212> PRT
<213> Homo sapien

<400> 680
 Met Met Asp Ser Pro Phe Leu Glu Leu Trp Gln Ser Lys Ala Val
   1               5                  10                  15

 Ser Ile Arg Glu Gln Leu Gly Leu Gly Asp Arg Pro Asn Asp Ser
                  20                  25                  30

 Tyr Cys Tyr Asn Ser Ala Lys Asn Ser Thr Val Leu Gln Gly Val
                  35                  40                  45

 Thr Phe Gly Gly Ile Pro Thr Val Leu Leu Ile Asp Val Ser Cys
                  50                  55                  60

 Phe Leu Phe Leu Ile Leu Val Phe Ser Ile Ile Arg Arg Arg Phe
                  65                  70                  75

 Trp Asp Tyr Gly Arg Ile Ala Leu Val Ser Glu Ala Asp Ser Glu
                  80                  85                  90

 Ser Arg Phe Gln Arg Leu Ser Ser Thr Ser Ser Ser Gly Gln Gln
                  95                 100                 105

 Asp Phe Glu Asn Glu Leu Gly Cys Cys Pro Trp Leu Thr Ala Ile
                 110                 115                 120

 Phe Arg Leu His Asp Asp Gln Ile Leu Glu Trp Cys Gly Glu Asp
                 125                 130                 135

 Ala Ile His Tyr Leu Ser Phe Gln Arg His Ile Ile Phe Leu Leu
                 140                 145                 150

 Val Val Val Ser Phe Leu Ser Leu Cys Val Ile Leu Pro Val Asn
                 155                 160                 165

 Leu Ser Gly Asp Leu Leu Asp Lys Asp Pro Tyr Ser Phe Gly Arg
                 170                 175                 180

 Thr Thr Ile Ala Asn Leu Gln Thr Asp Asn Asp Leu Leu Trp Leu
                 185                 190                 195

 His Thr Ile Phe Ala Val Ile Tyr Leu Phe Phe Thr Val Gly Phe
                 200                 205                 210

 Met Arg His His Thr Gln Ser Ile Lys Tyr Lys Glu Glu Asn Leu
                 215                 220                 225

 Val Arg Arg Thr Leu Phe Ile Thr Gly Leu Pro Arg Asp Ala Arg
                 230                 235                 240

 Lys Glu Thr Val Glu Ser His Phe Arg Asp Ala Tyr Pro Thr Cys
                 245                 250                 255

 Glu Val Val Asp Val Gln Leu Cys Tyr Asn Val Ala Lys Leu Ile
                 260                 265                 270

 Tyr Leu Cys Lys Glu Lys Lys Lys Thr Glu Lys Ser Leu Thr Tyr
                 275                 280                 285

 Tyr Thr Asn Leu Gln Val Lys Thr Gly Gln Arg Thr Leu Ile Asn
                 290                 295                 300

 Pro Lys Pro Cys Gly Gln Phe Cys Cys Cys Glu Val Leu Gly Cys
                 305                 310                 315

 Glu Trp Glu Asp Ala Ile Ser Tyr Tyr Thr Arg Met Lys Asp Arg
                 320                 325                 330

 Leu Leu Glu Arg Ile Thr Glu Glu Glu Arg His Val Gln Asp Gln
                 335                 340                 345

 Pro Leu Gly Met Ala Phe Val Thr Phe Gln Glu Lys Ser Met Ala
                 350                 355                 360

 Thr Tyr Ile Leu Lys Asp Phe Asn Ala Cys Lys Cys Gln Ser Leu
                 365                 370                 375

 Gln Cys Lys Gly Glu Pro Gln Pro Ser Ser His Ser Arg Glu Leu
                 380                 385                 390

 Tyr Thr Ser Lys Trp Thr Val Thr Phe Ala Ala Asp Pro Glu Asp
                 395                 400                 405

 Ile Cys Trp Lys Asn Leu Ser Ile Gln Gly Leu Arg Trp Trp Leu
                 410                 415                 420

 Gln Trp Leu Gly Ile Asn Phe Thr Leu Phe Leu Gly Leu Phe Phe
                 425                 430                 435

 Leu Thr Thr Pro Ser Ile Ile Leu Ser Thr Met Asp Lys Phe Asn
                 440                 445                 450

 Val Thr Lys Pro Ile His Ala Leu Asn Asn Pro Ile Ile Ser Gln
                 455                 460                 465

 Phe Phe Pro Thr Leu Leu Leu Trp Ser Phe Ser Ala Leu Leu Pro
                 470                 475                 480

 Ser Ile Val Tyr Tyr Ser Thr Leu Leu Glu Ser His Trp Thr Lys
                 485                 490                 495

 Ser Gly Glu Asn Gln Ile Met Met Thr Lys Val Tyr Ile Phe Leu
                 500                 505                 510

 Ile Phe Met Val Leu Ile Leu Pro Ser Leu Gly Leu Thr Ser Leu
                 515                 520                 525

 Asp Phe Phe Phe Arg Trp Leu Phe Asp Lys Thr Ser Ser Glu Ala
                 530                 535                 540

 Ser Ile Arg Leu Glu Cys Val Phe Leu Pro Asp Gln Gly Ala Phe
                 545                 550                 555

 Phe Val Asn Tyr Val Ile Ala Ser Ala Phe Ile Gly Asn Gly Met
                 560                 565                 570

 Glu Leu Leu Arg Leu Pro Gly Leu Ile Leu Tyr Thr Phe Arg Met
                 575                 580                 585

 Ile Met Ala Lys Thr Ala Ala Asp Arg Arg Asn Val Lys Gln Asn
                 590                 595                 600

 Gln Ala Phe Gln Tyr Glu Phe Gly Ala Met Tyr Ala Trp Met Leu
                 605                 610                 615

 Cys Val Phe Thr Val Ile Val Ala Tyr Ser Ile Thr Cys Pro Ile
                 620                 625                 630

 Ile Ala Pro Phe Gly Leu Ile Tyr Ile Leu Leu Lys His Met Val
                 635                 640                 645

 Asp Arg His Asn Leu Tyr Phe Val Tyr Leu Pro Ala Lys Leu Glu
                 650                 655                 660

 Lys Gly Ile His Phe Ala Ala Val Asn Gln Ala Leu Ala Ala Pro
                 665                 670                 675

 Ile Leu Cys Leu Phe Trp Leu Tyr Phe Phe Ser Phe Leu Arg Leu
                 680                 685                 690

 Gly Met Lys Ala Pro Ala Thr Leu Phe Thr Phe Leu Val Leu Leu
                 695                 700                 705

 Leu Thr Ile Leu Val Cys Leu Ala His Thr Cys Phe Gly Cys Phe
                 710                 715                 720

 Lys His Leu Ser Pro Leu Asn Tyr Lys Thr Glu Glu Pro Ala Ser
                 725                 730                 735

 Asp Lys Gly Ser Glu Ala Glu Ala His Met Pro Pro Pro Phe Thr
                 740                 745                 750

 Pro Tyr Val Pro Arg Ile Leu Asn Gly Leu Ala Ser Glu Arg Thr
                 755                 760                 765

 Ala Leu Ser Pro Gln Gln Gln Gln Gln Gln Thr Tyr Gly Ala Ile
                 770                 775                 780

 His Asn Ile Ser Gly Thr Ile Pro Gly Gln Cys Leu Ala Gln Ser
                 785                 790                 795

 Ala Thr Gly Ser Val Ala Ala Ala Pro Gln Glu Ala
                 800                 805

<210> 681
<211> 1830
<212> DNA
<213> Homo sapien

<400> 681
 ggggagttga aacctaattt tgtggcgtag cagctatgca gcttgaaatc 50

 caagtagcac taaattttat tatttcgtat ttgtacaata agcttcccag 100

 gagacgtgtc aacatttttg gtgaagaact tgaaagactt cttaagaaga 150

 aatatgaagg gcactggtat cctgaaaagc catacaaagg atcggggttt 200

 agatgtatac acatagggga gaaagtggac ccagtgattg aacaagcatc 250

 caaagagagt ggtttggaca ttgatgatgt tcgtggcaat ctgccacagg 300

 atcttagtgt ttggatcgac ccatttgagg tttcttacca aattggtgaa 350

 aagggaccag tgaaggtgct ttacgtggat gataataatg aaaatggatg 400

 tgagttggat aaggagatca aaaacagctt taacccagag gcccaggttt 450

 ttatgcccat aagtgaccca gcctcatcag tgtccagctc tccatcgcct 500

 ccttttggtc actctgctgc tgtaagccct accttcatgc cccggtccac 550

 tcagccttta acctttacca ctgccacttt tgctgccacc aagttcggct 600

 ctaccaaaat gaagaatagt ggccgtagca acaaggttgc acgtacttct 650

 cccatcaacc tcggcttgaa tgtgaatgac ctcttgaagc agaaagccat 700

 ctcttcctca atgcactctc tgtatgggct tggcttgggt agccagcagc 750

 agccacagca acagcagcag ccagcccagc cgccaccgcc accaccacca 800

 ccacagcagc aacaacagca gaaaacctct gctctttctc ctaatgccaa 850

 ggaatttatt tttcctaata tgcagggtca aggtagtagt accaatggaa 900

 tgttcccagg tgacagcccc cttaacctca gtcctctcca gtacagtaat 950

 gcctttgatg tgtttgcagc ctatggaggc ctcaatgaga agtcttttgt 1000

 agatggcttg aattttagct taaataacat gcagtattct aaccagcaat 1050

 tccagcctgt tatggctaac taaaaaaaag aaaatgtatc gtacaagtta 1100

 aaatgcacgg gcccaagggg gatttttttt ttcacctcct tgagaatttt 1150

 tttttttaag cttatagtaa ggatacattc aagcttggtt aaaaaaataa 1200

 taataaaaca tgcatcattt ttcatttgcc aaccaagcac aaagttattt 1250

 tatactgact gtatatttta aagtatactc tcagatatgg cctcttacag 1300

 tatttaagat atagcaagga catggctgat ttttttttat aaaaattggc 1350

 actaataagt gggtttattg gtcttttcta attgtataat ttaatttagt 1400

 acaaagtttg taaaatatca gaggatatat atatattgtt tctacgacat 1450

 ggtattgcat ttatatcttt ttactacagt gatctgtgac agcagcagct 1500

 tcatgttgta ttttttttac tgaaattgta aaatatccat cttaaagaca 1550

 tcaactattc taaaaattgt gtacaggata ttcctttagt ggtggaatta 1600

 aaatgtacga atacttgctt tttcaaaaaa atgtattttc tgttaaaagt 1650

 ttaaagattt ttgctatata ttatggaaga aaaatgtaat cgtaaatatt 1700

 aattttgtac ctatattgtg caatacttga aaaaaacggt ataaaagtat 1750

 tttgagtcag tgtcttacat gttaagaggg actgaaatag tttatattaa 1800

 gtttgtatta aaattcttta aaattaaaaa 1830

<210> 682
<211> 345
<212> PRT
<213> Homo sapien

<400> 682
 Met Gln Leu Glu Ile Gln Val Ala Leu Asn Phe Ile Ile Ser Tyr
   1               5                  10                  15

 Leu Tyr Asn Lys Leu Pro Arg Arg Arg Val Asn Ile Phe Gly Glu
                  20                  25                  30

 Glu Leu Glu Arg Leu Leu Lys Lys Lys Tyr Glu Gly His Trp Tyr
                  35                  40                  45

 Pro Glu Lys Pro Tyr Lys Gly Ser Gly Phe Arg Cys Ile His Ile
                  50                  55                  60

 Gly Glu Lys Val Asp Pro Val Ile Glu Gln Ala Ser Lys Glu Ser
                  65                  70                  75

 Gly Leu Asp Ile Asp Asp Val Arg Gly Asn Leu Pro Gln Asp Leu
                  80                  85                  90

 Ser Val Trp Ile Asp Pro Phe Glu Val Ser Tyr Gln Ile Gly Glu
                  95                 100                 105

 Lys Gly Pro Val Lys Val Leu Tyr Val Asp Asp Asn Asn Glu Asn
                 110                 115                 120

 Gly Cys Glu Leu Asp Lys Glu Ile Lys Asn Ser Phe Asn Pro Glu
                 125                 130                 135

 Ala Gln Val Phe Met Pro Ile Ser Asp Pro Ala Ser Ser Val Ser
                 140                 145                 150

 Ser Ser Pro Ser Pro Pro Phe Gly His Ser Ala Ala Val Ser Pro
                 155                 160                 165

 Thr Phe Met Pro Arg Ser Thr Gln Pro Leu Thr Phe Thr Thr Ala
                 170                 175                 180

 Thr Phe Ala Ala Thr Lys Phe Gly Ser Thr Lys Met Lys Asn Ser
                 185                 190                 195

 Gly Arg Ser Asn Lys Val Ala Arg Thr Ser Pro Ile Asn Leu Gly
                 200                 205                 210

 Leu Asn Val Asn Asp Leu Leu Lys Gln Lys Ala Ile Ser Ser Ser
                 215                 220                 225

 Met His Ser Leu Tyr Gly Leu Gly Leu Gly Ser Gln Gln Gln Pro
                 230                 235                 240

 Gln Gln Gln Gln Gln Pro Ala Gln Pro Pro Pro Pro Pro Pro Pro
                 245                 250                 255

 Pro Gln Gln Gln Gln Gln Gln Lys Thr Ser Ala Leu Ser Pro Asn
                 260                 265                 270

 Ala Lys Glu Phe Ile Phe Pro Asn Met Gln Gly Gln Gly Ser Ser
                 275                 280                 285

 Thr Asn Gly Met Phe Pro Gly Asp Ser Pro Leu Asn Leu Ser Pro
                 290                 295                 300

 Leu Gln Tyr Ser Asn Ala Phe Asp Val Phe Ala Ala Tyr Gly Gly
                 305                 310                 315

 Leu Asn Glu Lys Ser Phe Val Asp Gly Leu Asn Phe Ser Leu Asn
                 320                 325                 330

 Asn Met Gln Tyr Ser Asn Gln Gln Phe Gln Pro Val Met Ala Asn
                 335                 340                 345

<210> 683
<211> 1530
<212> DNA
<213> Homo sapien

<400> 683
 aatcctggaa caaggctaca gcgtcgaaga tccccagcgc tgcgggctcg 50

 gagagcagtc ctaacggcgc ctcgtacgct agtgtcctcc cttttcagtc 100

 cgcgtccctc cctgggccgg gctggcactc ttgccttccc cgtccctcat 150

 ggcgctgctc cgacgcccga cggtgtccag tgatttggag aatattgaca 200

 caggagttaa ttctaaagtt aagagtcatg tgactattag gcgaactgtt 250

 ttagaagaaa ttggaaatag agttacaacc agagcagcac aagtagctaa 300

 gaaagctcag aacaccaaag ttccagttca acccaccaaa acaacaaatg 350

 tcaacaaaca actgaaacct actgcttctg tcaaaccagt acagatggaa 400

 aagttggctc caaagggtcc ttctcccaca cctgaggatg tctccatgaa 450

 ggaagagaat ctctgccaag ctttttctga tgccttgctc tgcaaaatcg 500

 aggacattga taacgaagat tgggagaacc ctcagctctg cagtgactac 550

 gttaaggata tctatcagta tctcaggcag ctggaggttt tgcagtccat 600

 aaacccacat ttcttagatg gaagagatat aaatggacgc atgcgtgcca 650

 tcctagtgga ttggctggta caagtccact ccaagtttag gcttctgcag 700

 gagactctgt acatgtgcgt tggcattatg gatcgatttt tacaggttca 750

 gccagtttcc cggaagaagc ttcaattagt tgggattact gctctgctct 800

 tggcttccaa gtatgaggag atgttttctc caaatattga agactttgtt 850

 tacatcacag acaatgctta taccagttcc caaatccgag aaatggaaac 900

 tctaattttg aaagaattga aatttgagtt gggtcgaccc ttgccactac 950

 acttcttaag gcgagcatca aaagccgggg aggttgatgt tgaacagcac 1000

 actttagcca agtatttgat ggagctgact ctcatcgact atgatatggt 1050

 gcattatcat ccttctaagg tagcagcagc tgcttcctgc ttgtctcaga 1100

 aggttctagg acaaggaaaa tggaacttaa agcagcagta ttacacagga 1150

 tacacagaga atgaagtatt ggaagtcatg cagcacatgg ccaagaatgt 1200

 ggtgaaagta aatgaaaact taactaaatt catcgccatc aagaataagt 1250

 atgcaagcag caaactcctg aagatcagca tgatccctca gctgaactca 1300

 aaagccgtca aagaccttgc ctccccactg ataggaaggt cctaggctgc 1350

 cgtgggccct ggggatgtgt gcttcattgt gccctttttc ttattggttt 1400

 agaactcttg attttgtaca tagtcctctg gtctatctca tgaaacctct 1450

 tctcagacca gttttctaaa catatattga ggaaaaataa agcgattggt 1500

 ttttcttaag gtaaaaaaaa aaaaaaaaaa 1530

<210> 684
<211> 398
<212> PRT
<213> Homo sapien

<400> 684
 Met Ala Leu Leu Arg Arg Pro Thr Val Ser Ser Asp Leu Glu Asn
   1               5                  10                  15

 Ile Asp Thr Gly Val Asn Ser Lys Val Lys Ser His Val Thr Ile
                  20                  25                  30

 Arg Arg Thr Val Leu Glu Glu Ile Gly Asn Arg Val Thr Thr Arg
                  35                  40                  45

 Ala Ala Gln Val Ala Lys Lys Ala Gln Asn Thr Lys Val Pro Val
                  50                  55                  60

 Gln Pro Thr Lys Thr Thr Asn Val Asn Lys Gln Leu Lys Pro Thr
                  65                  70                  75

 Ala Ser Val Lys Pro Val Gln Met Glu Lys Leu Ala Pro Lys Gly
                  80                  85                  90

 Pro Ser Pro Thr Pro Glu Asp Val Ser Met Lys Glu Glu Asn Leu
                  95                 100                 105

 Cys Gln Ala Phe Ser Asp Ala Leu Leu Cys Lys Ile Glu Asp Ile
                 110                 115                 120

 Asp Asn Glu Asp Trp Glu Asn Pro Gln Leu Cys Ser Asp Tyr Val
                 125                 130                 135

 Lys Asp Ile Tyr Gln Tyr Leu Arg Gln Leu Glu Val Leu Gln Ser
                 140                 145                 150

 Ile Asn Pro His Phe Leu Asp Gly Arg Asp Ile Asn Gly Arg Met
                 155                 160                 165

 Arg Ala Ile Leu Val Asp Trp Leu Val Gln Val His Ser Lys Phe
                 170                 175                 180

 Arg Leu Leu Gln Glu Thr Leu Tyr Met Cys Val Gly Ile Met Asp
                 185                 190                 195

 Arg Phe Leu Gln Val Gln Pro Val Ser Arg Lys Lys Leu Gln Leu
                 200                 205                 210

 Val Gly Ile Thr Ala Leu Leu Leu Ala Ser Lys Tyr Glu Glu Met
                 215                 220                 225

 Phe Ser Pro Asn Ile Glu Asp Phe Val Tyr Ile Thr Asp Asn Ala
                 230                 235                 240

 Tyr Thr Ser Ser Gln Ile Arg Glu Met Glu Thr Leu Ile Leu Lys
                 245                 250                 255

 Glu Leu Lys Phe Glu Leu Gly Arg Pro Leu Pro Leu His Phe Leu
                 260                 265                 270

 Arg Arg Ala Ser Lys Ala Gly Glu Val Asp Val Glu Gln His Thr
                 275                 280                 285

 Leu Ala Lys Tyr Leu Met Glu Leu Thr Leu Ile Asp Tyr Asp Met
                 290                 295                 300

 Val His Tyr His Pro Ser Lys Val Ala Ala Ala Ala Ser Cys Leu
                 305                 310                 315

 Ser Gln Lys Val Leu Gly Gln Gly Lys Trp Asn Leu Lys Gln Gln
                 320                 325                 330

 Tyr Tyr Thr Gly Tyr Thr Glu Asn Glu Val Leu Glu Val Met Gln
                 335                 340                 345

 His Met Ala Lys Asn Val Val Lys Val Asn Glu Asn Leu Thr Lys
                 350                 355                 360

 Phe Ile Ala Ile Lys Asn Lys Tyr Ala Ser Ser Lys Leu Leu Lys
                 365                 370                 375

 Ile Ser Met Ile Pro Gln Leu Asn Ser Lys Ala Val Lys Asp Leu
                 380                 385                 390

 Ala Ser Pro Leu Ile Gly Arg Ser
                 395

<210> 685
<211> 6972
<212> DNA
<213> Homo sapien

<400> 685
 cgcccccgcc tctgagctcc cttcccatgg cggccctagt gttggaggac 50

 gggtcggtcc tgcggggcca gccctttggg gccgccgtgt cgactgccgg 100

 ggaagtggtg tttcaaaccg gcatggtcgg ctaccccgag gccctcactg 150

 atccctccta caaggcacag atcttagtgc tcacctatcc tctgatcggc 200

 aactatggca tccccccaga tgaaatggat gagttcggtc tctgcaagtg 250

 gtttgaatcc tcgggcatcc acgtagcagc actggtagtg ggagagtgct 300

 gtcctactcc cagccactgg agtgccaccc gcaccctgca tgagtggctg 350

 cagcagcatg gcatccctgg cttgcaagga gtagacactc gggagctgac 400

 caagaagttg cgggaacagg ggtctctgct ggggaagctg gtccagaatg 450

 gaacagaacc ttcatccctg ccattcttgg accccaatgc ccgccccctg 500

 gtaccagagg tctccattaa gactccacgg gtattcaata cagggggtgc 550

 ccctcggatc cttgctttgg actgtggcct caagtataat cagatccgat 600

 gcctctgcca gcgtggggct gaggtcactg tggtaccctg ggaccatgca 650

 ctagacagcc aagagtatga gggtctcttc ttaagtaatg ggcctggtga 700

 ccctgcctcc tatcccagtg tcgtatccac actgagccgt gttttatctg 750

 agcctaatcc ccgacctgtc tttgggatct gcctgggaca ccagctattg 800

 gccttagcca ttggggccaa gacttacaag atgagatatg ggaaccgagg 850

 ccataaccag ccctgcttgt tggtgggctc tgggcgctgc tttctgacat 900

 cccagaacca tgggtttgct gtggagacag actcactgcc agcagactgg 950

 gctcctctct tcaccaacgc caatgatggt tccaatgaag gcattgtgca 1000

 caacagcttg cctttcttca gtgtccagtt tcacccagag caccaagctg 1050

 gcccttcaga tatggaactg cttttcgata tctttctgga aactgtgaaa 1100

 gaggccacag ctgggaaccc tgggggccag acagttagag agcggctgac 1150

 tgagcgcctc tgtccccctg ggattcccac tcccggctct ggacttccac 1200

 caccacgaaa ggttctgatc ctgggctcag ggggcctctc cattggccaa 1250

 gctggagaat ttgactactc gggctctcag gcaattaagg ccctgaagga 1300

 ggaaaacatc cagacgttgc tgatcaaccc caatattgcc acagtgcaga 1350

 cctcccaggg gctggccgac aaggtctatt ttcttcccat aacacctcat 1400

 tatgtaaccc aggtgatacg taatgaacgc cccgatggtg tgttactgac 1450

 ttttgggggc cagactgctc tgaactgtgg tgtggagctg accaaggccg 1500

 gggtgctggc tcggtatggg gtccgggtcc tgggcacacc agtggagacc 1550

 attgagctga ccgaggatcg acgggccttt gctgccagaa tggcagagat 1600

 cggagagcat gtggccccga gcgaggcagc aaattctctt gaacaggccc 1650

 aggcagccgc tgaacggctg gggtaccctg tgctagtgcg tgcagccttt 1700

 gccctgggtg gcctgggctc tggctttgcc tctaacaggg aggagctctc 1750

 tgctctcgtg gccccagctt ttgcccatac cagccaagtg ctagtagaca 1800

 agtctctgaa gggatggaag gagattgagt acgaggtggt gagagacgcc 1850

 tatggcaact gtgtcacggt gtgtaacatg gagaacttgg acccactggg 1900

 catccacact ggtgagtcca tagtggtggc ccctagccag acactgaatg 1950

 acagggagta tcagctcctg aggcagacag ctatcaaggt gacccagcac 2000

 ctgggaattg ttggggagtg caatgtgcag tatgccttga accctgagtc 2050

 tgagcagtat tacatcattg aagtgaatgc caggctctct cgcagctctg 2100

 ccctggccag taaggccaca ggttatccac tggcttatgt ggcagccaag 2150

 ctagcattgg gcatcccttt gcctgagctc aggaactctg tgacaggggg 2200

 tacagcagcc tttgaaccca gcgtggatta ttgtgtggtg aagattcctc 2250

 gatgggacct tagcaagttc ctgcgagtca gcacaaagat tgggagctgc 2300

 atgaagagcg ttggtgaagt catgggcatt gggcgttcat ttgaggaggc 2350

 cttccagaag gccctgcgca tggtggatga gaactgtgtg ggctttgatc 2400

 acacagtgaa accagtcagc gatatggagt tggagactcc aacagataag 2450

 cggatttttg tggtggcagc tgctttgtgg gctggttatt cagtggaccg 2500

 cctgtatgag ctcacacgca tcgaccgctg gttcctgcac cgaatgaagc 2550

 gtatcatcgc acatgcccag ctgctagaac aacaccgtgg acagcctttg 2600

 ccgccagacc tgctgcaaca ggccaagtgt cttggcttct cagacaaaca 2650

 gattgccctt gcagttctga gcacagagct ggctgttcgc aagctgcgtc 2700

 aggaactggg gatctgtcca gcagtgaaac agattgacac agttgcagct 2750

 gagtggccag cccagacaaa ttacctatac ctaacgtatt ggggcaccac 2800

 ccatgacctc acctttcgaa cacctcatgt cctagtcctt ggctctggcg 2850

 tctaccgtat tggctctagc gttgaatttg actggtgtgc tgtaggctgc 2900

 atccagcagc tccgaaagat gggatataag accatcatgg tgaactataa 2950

 cccagagaca gtcagcaccg actatgacat gtgtgatcga ctctactttg 3000

 atgagatctc ttttgaggtg gtgatggaca tctatgagct cgagaaccct 3050

 gaaggtgtga tcctatccat gggtggacag ctgcccaaca acatggccat 3100

 ggcgttgcat cggcagcagt gccgggtgct gggcacctcc cctgaagcca 3150

 ttgactcggc tgagaaccgt ttcaagtttt cccggctcct tgacaccatt 3200

 ggtatcagcc agcctcagtg gagggagctc agtgacctcg agtctgctcg 3250

 ccaattctgc cagaccgtgg ggtacccctg tgtggtgcgc ccctcctatg 3300

 tgctgagcgg tgctgctatg aatgtggcct acacggatgg agacctggag 3350

 cgcttcctga gcagcgcagc agccgtctcc aaagagcatc ccgtggtcat 3400

 ctccaagttc atccaggagg ctaaggagat tgacgtggat gccgtggcct 3450

 ctgatggtgt ggtggcagcc atcgccatct ctgagcatgt ggagaatgca 3500

 ggtgtgcatt caggtgatgc gacgctggtg acccccccac aagatatcac 3550

 tgccaaaacc ctggagcgga tcaaagccat tgtgcatgct gtgggccagg 3600

 agctacaggt cacaggaccc ttcaatctgc agctcattgc caaggatgac 3650

 cagctgaaag ttattgaatg caacgtacgt gtctctcgct ccttcccctt 3700

 cgtttccaag acactgggtg tggacctagt agccttggcc acgcgggtca 3750

 tcatggggga agaagtggaa cctgtggggc taatgactgg ttctggagtc 3800

 gtgggagtaa aggtgcctca gttctccttc tcccgcttgg cgggtgctga 3850

 cgtggtgttg ggtgtggaaa tgaccagtac tggggaggtg gccggctttg 3900

 gggagagccg ctgtgaggca tacctcaagg ccatgctaag cactggcttt 3950

 aagatcccca agaagaatat cctgctgacc attggcagct ataagaacaa 4000

 aagcgagctg ctcccaactg tgcggctact ggagagcctg ggctacagcc 4050

 tctatgccag tctcggcaca gctgacttct acactgagca tggcgtcaag 4100

 gtaacagctg tggactggca ctttgaggag gctgtggatg gtgagtgccc 4150

 accacagcgg agcatcctgg agcagctagc tgagaaaaac tttgagctgg 4200

 tgattaacct gtcaatgcgt ggagctgggg gccggcgtct ctcttccttt 4250

 gtcaccaagg gctaccgcac ccgacgcttg gccgctgact tctccgtgcc 4300

 cctaatcatc gatatcaagt gcaccaaact ctttgtggag gccctaggcc 4350

 agatcgggcc agcccctcct ttgaaggtgc atgttgactg tatgacctcc 4400

 caaaagcttg tgcgactgcc gggattgatt gatgtccatg tgcacctgcg 4450

 ggaaccaggt gggacacata aggaggactt tgcttcaggc acagccgctg 4500

 ccctggctgg gggtatcacc atggtgtgtg ccatgcctaa tacccggccc 4550

 cccatcattg acgcccctgc tctggccctg gcccagaagc tggcagaggc 4600

 tggcgcccgg tgcgactttg cgctattcct tggggcctcg tctgaaaatg 4650

 caggaacctt gggcaccgtg gccgggtctg cagccgggct gaagctttac 4700

 ctcaatgaga ccttctctga gctgcggctg gacagcgtgg tccagtggat 4750

 ggagcatttc gagacatggc cctcccacct ccccattgtg gctcacgcag 4800

 agcagcaaac cgtggctgct gtcctcatgg tggctcagct cactcagcgc 4850

 tcagtgcaca tatgtcacgt ggcacggaag gaggagatcc tgctaattaa 4900

 agctgcaaag gcacggggct tgccagtgac ctgcgaggtg gctccccacc 4950

 acctgttcct aagccatgat gacctggagc gcctggggcc tgggaagggg 5000

 gaggtccggc ctgagcttgg ctcccgccag gatgtggaag ccctgtggga 5050

 gaacatggct gtcatcgact gctttgcctc agaccatgct ccccatacct 5100

 tggaggagaa gtgtgggtcc aggcccccac ctgggttccc agggttagag 5150

 accatgctgc cactactcct gacggctgta agcgagggcc ggctcagcct 5200

 ggacgacctg ctgcagcgat tgcaccacaa tcctcggcgc atctttcacc 5250

 tgcccccgca ggaggacacc tatgtggagg tggatctgga gcatgagtgg 5300

 acaattccca gccacatgcc cttctccaag gcccactgga caccttttga 5350

 agggcagaaa gtgaagggca ccgtccgccg tgtggtcctg cgaggggagg 5400

 ttgcctatat cgatgggcag gttctggtac ccccgggcta tggacaggat 5450

 gtacggaagt ggccacaggg ggctgttcct cagctcccac cctcagcccc 5500

 tgccactagt gagatgacca cgacacctga aagaccccgc cgtggcatcc 5550

 cagggcttcc tgatggccgc ttccatctgc cgccccgaat ccatcgagcc 5600

 tccgacccag gtttgccagc tgaggagcca aaggagaagt cctctcggaa 5650

 ggtagccgag ccagagctga tgggaacccc tgatggcacc tgctaccctc 5700

 caccaccagt accgagacag gcatctcccc agaacctggg gacccctggc 5750

 ttgctgcacc cccagacctc acccctgctg cactcattag tgggccaaca 5800

 tatcctgtcc gtccagcagt tcaccaagga tcagatgtct cacctgttca 5850

 atgtggcaca cacactgcgt atgatggtgc agaaggagcg gagcctcgac 5900

 atcctgaagg ggaaggtcat ggcctccatg ttctatgaag tgagcacacg 5950

 gaccagcagc tcctttgcag cagccatggc ccggctggga ggtgctgtgc 6000

 tcagcttctc ggaagccaca tcgtccgtcc agaagggcga atccctggct 6050

 gactccgtgc agaccatgag ctgctatgcc gacgtcgtcg tgctccggca 6100

 cccccagcct ggagcagtgg agctggccgc caagcactgc cggaggccag 6150

 tgatcaatgc tggggatggg gtcggagagc accccaccca ggccctgctg 6200

 gacatcttca ccatccgtga ggagctggga actgtcaatg gcatgacgat 6250

 cacgatggtg ggtgacctga agcacggacg cacagtacat tccctggcct 6300

 gcctgctcac ccagtatcgt gtcagcctgc gctacgtggc acctcccagc 6350

 ctgcgcatgc cacccactgt gcgggccttc gtggcctccc gcggcaccaa 6400

 gcaggaggaa ttcgagagca ttgaggaggc gctgcctgac actgatgtgc 6450

 tctacatgac tcgaatccag aaggaacgat ttggctctac ccaggagtac 6500

 gaagcttgct ttggtcagtt catcctcact ccccacatca tgacccgggc 6550

 caagaagaag atggtggtga tgcacccgat gccccgtgtc aacgagataa 6600

 gcgtggaagt ggactcggat ccccgcgcag cctacttccg ccaggctgag 6650

 aacggcatgt acatccgcat ggctctgtta gccaccgtgc tgggccgttt 6700

 ctaggggcct ggcttcctca gcctcttctc tttaggccca gctgctgggc 6750

 aaggaattcc agtgcctcct acgggggcag cacacttaga tattcctgga 6800

 catccagatt gctcacatgt gctgaccaca cttcaggctc tggactggag 6850

 ctctctggca tgggggtggg gcctcagatg ctggggccca gtctgcccca 6900

 tcttcattcc tgcaccttaa acctgtacag tcatttttct actgacttaa 6950

 taaacagccg agctgtccct tg 6972

<210> 686
<211> 2000
<212> PRT
<213> Homo sapien

<400> 686
 Met Ala Ala Leu Val Leu Glu Asp Gly Ser Val Leu Arg Gly Gln
   1               5                  10                  15

 Pro Phe Gly Ala Ala Val Ser Thr Ala Gly Glu Val Val Phe Gln
                  20                  25                  30

 Thr Gly Met Val Gly Tyr Pro Glu Ala Leu Thr Asp Pro Ser Tyr
                  35                  40                  45

 Lys Ala Gln Ile Leu Val Leu Thr Tyr Pro Leu Ile Gly Asn Tyr
                  50                  55                  60

 Gly Ile Pro Pro Asp Glu Met Asp Glu Phe Gly Leu Cys Lys Trp
                  65                  70                  75

 Phe Glu Ser Ser Gly Ile His Val Ala Ala Leu Val Val Gly Glu
                  80                  85                  90

 Cys Cys Pro Thr Pro Ser His Trp Ser Ala Thr Arg Thr Leu His
                  95                 100                 105

 Glu Trp Leu Gln Gln His Gly Ile Pro Gly Leu Gln Gly Val Asp
                 110                 115                 120

 Thr Arg Glu Leu Thr Lys Lys Leu Arg Glu Gln Gly Ser Leu Leu
                 125                 130                 135

 Gly Lys Leu Val Gln Asn Gly Thr Glu Pro Ser Ser Leu Pro Phe
                 140                 145                 150

 Leu Asp Pro Asn Ala Arg Pro Leu Val Pro Glu Val Ser Ile Lys
                 155                 160                 165

 Thr Pro Arg Val Phe Asn Thr Gly Gly Ala Pro Arg Ile Leu Ala
                 170                 175                 180

 Leu Asp Cys Gly Leu Lys Tyr Asn Gln Ile Arg Cys Leu Cys Gln
                 185                 190                 195

 Arg Gly Ala Glu Val Thr Val Val Pro Trp Asp His Ala Leu Asp
                 200                 205                 210

 Ser Gln Glu Tyr Glu Gly Leu Phe Leu Ser Asn Gly Pro Gly Asp
                 215                 220                 225

 Pro Ala Ser Tyr Pro Ser Val Val Ser Thr Leu Ser Arg Val Leu
                 230                 235                 240

 Ser Glu Pro Asn Pro Arg Pro Val Phe Gly Ile Cys Leu Gly His
                 245                 250                 255

 Gln Leu Leu Ala Leu Ala Ile Gly Ala Lys Thr Tyr Lys Met Arg
                 260                 265                 270

 Tyr Gly Asn Arg Gly His Asn Gln Pro Cys Leu Leu Val Gly Ser
                 275                 280                 285

 Gly Arg Cys Phe Leu Thr Ser Gln Asn His Gly Phe Ala Val Glu
                 290                 295                 300

 Thr Asp Ser Leu Pro Ala Asp Trp Ala Pro Leu Phe Thr Asn Ala
                 305                 310                 315

 Asn Asp Gly Ser Asn Glu Gly Ile Val His Asn Ser Leu Pro Phe
                 320                 325                 330

 Phe Ser Val Gln Phe His Pro Glu His Gln Ala Gly Pro Ser Asp
                 335                 340                 345

 Met Glu Leu Leu Phe Asp Ile Phe Leu Glu Thr Val Lys Glu Ala
                 350                 355                 360

 Thr Ala Gly Asn Pro Gly Gly Gln Thr Val Arg Glu Arg Leu Thr
                 365                 370                 375

 Glu Arg Leu Cys Pro Pro Gly Ile Pro Thr Pro Gly Ser Gly Leu
                 380                 385                 390

 Pro Pro Pro Arg Lys Val Leu Ile Leu Gly Ser Gly Gly Leu Ser
                 395                 400                 405

 Ile Gly Gln Ala Gly Glu Phe Asp Tyr Ser Gly Ser Gln Ala Ile
                 410                 415                 420

 Lys Ala Leu Lys Glu Glu Asn Ile Gln Thr Leu Leu Ile Asn Pro
                 425                 430                 435

 Asn Ile Ala Thr Val Gln Thr Ser Gln Gly Leu Ala Asp Lys Val
                 440                 445                 450

 Tyr Phe Leu Pro Ile Thr Pro His Tyr Val Thr Gln Val Ile Arg
                 455                 460                 465

 Asn Glu Arg Pro Asp Gly Val Leu Leu Thr Phe Gly Gly Gln Thr
                 470                 475                 480

 Ala Leu Asn Cys Gly Val Glu Leu Thr Lys Ala Gly Val Leu Ala
                 485                 490                 495

 Arg Tyr Gly Val Arg Val Leu Gly Thr Pro Val Glu Thr Ile Glu
                 500                 505                 510

 Leu Thr Glu Asp Arg Arg Ala Phe Ala Ala Arg Met Ala Glu Ile
                 515                 520                 525

 Gly Glu His Val Ala Pro Ser Glu Ala Ala Asn Ser Leu Glu Gln
                 530                 535                 540

 Ala Gln Ala Ala Ala Glu Arg Leu Gly Tyr Pro Val Leu Val Arg
                 545                 550                 555

 Ala Ala Phe Ala Leu Gly Gly Leu Gly Ser Gly Phe Ala Ser Asn
                 560                 565                 570

 Arg Glu Glu Leu Ser Ala Leu Val Ala Pro Ala Phe Ala His Thr
                 575                 580                 585

 Ser Gln Val Leu Val Asp Lys Ser Leu Lys Gly Trp Lys Glu Ile
                 590                 595                 600

 Glu Tyr Glu Val Val Arg Asp Ala Tyr Gly Asn Cys Val Thr Val
                 605                 610                 615

 Cys Asn Met Glu Asn Leu Asp Pro Leu Gly Ile His Thr Gly Glu
                 620                 625                 630

 Ser Ile Val Val Ala Pro Ser Gln Thr Leu Asn Asp Arg Glu Tyr
                 635                 640                 645

 Gln Leu Leu Arg Gln Thr Ala Ile Lys Val Thr Gln His Leu Gly
                 650                 655                 660

 Ile Val Gly Glu Cys Asn Val Gln Tyr Ala Leu Asn Pro Glu Ser
                 665                 670                 675

 Glu Gln Tyr Tyr Ile Ile Glu Val Asn Ala Arg Leu Ser Arg Ser
                 680                 685                 690

 Ser Ala Leu Ala Ser Lys Ala Thr Gly Tyr Pro Leu Ala Tyr Val
                 695                 700                 705

 Ala Ala Lys Leu Ala Leu Gly Ile Pro Leu Pro Glu Leu Arg Asn
                 710                 715                 720

 Ser Val Thr Gly Gly Thr Ala Ala Phe Glu Pro Ser Val Asp Tyr
                 725                 730                 735

 Cys Val Val Lys Ile Pro Arg Trp Asp Leu Ser Lys Phe Leu Arg
                 740                 745                 750

 Val Ser Thr Lys Ile Gly Ser Cys Met Lys Ser Val Gly Glu Val
                 755                 760                 765

 Met Gly Ile Gly Arg Ser Phe Glu Glu Ala Phe Gln Lys Ala Leu
                 770                 775                 780

 Arg Met Val Asp Glu Asn Cys Val Gly Phe Asp His Thr Val Lys
                 785                 790                 795

 Pro Val Ser Asp Met Glu Leu Glu Thr Pro Thr Asp Lys Arg Ile
                 800                 805                 810

 Phe Val Val Ala Ala Ala Leu Trp Ala Gly Tyr Ser Val Asp Arg
                 815                 820                 825

 Leu Tyr Glu Leu Thr Arg Ile Asp Arg Trp Phe Leu His Arg Met
                 830                 835                 840

 Lys Arg Ile Ile Ala His Ala Gln Leu Leu Glu Gln His Arg Gly
                 845                 850                 855

 Gln Pro Leu Pro Pro Asp Leu Leu Gln Gln Ala Lys Cys Leu Gly
                 860                 865                 870

 Phe Ser Asp Lys Gln Ile Ala Leu Ala Val Leu Ser Thr Glu Leu
                 875                 880                 885

 Ala Val Arg Lys Leu Arg Gln Glu Leu Gly Ile Cys Pro Ala Val
                 890                 895                 900

 Lys Gln Ile Asp Thr Val Ala Ala Glu Trp Pro Ala Gln Thr Asn
                 905                 910                 915

 Tyr Leu Tyr Leu Thr Tyr Trp Gly Thr Thr His Asp Leu Thr Phe
                 920                 925                 930

 Arg Thr Pro His Val Leu Val Leu Gly Ser Gly Val Tyr Arg Ile
                 935                 940                 945

 Gly Ser Ser Val Glu Phe Asp Trp Cys Ala Val Gly Cys Ile Gln
                 950                 955                 960

 Gln Leu Arg Lys Met Gly Tyr Lys Thr Ile Met Val Asn Tyr Asn
                 965                 970                 975

 Pro Glu Thr Val Ser Thr Asp Tyr Asp Met Cys Asp Arg Leu Tyr
                 980                 985                 990

 Phe Asp Glu Ile Ser Phe Glu Val Val Met Asp Ile Tyr Glu Leu
                 995                1000                1005

 Glu Asn Pro Glu Gly Val Ile Leu Ser Met Gly Gly Gln Leu Pro
                1010                1015                1020

 Asn Asn Met Ala Met Ala Leu His Arg Gln Gln Cys Arg Val Leu
                1025                1030                1035

 Gly Thr Ser Pro Glu Ala Ile Asp Ser Ala Glu Asn Arg Phe Lys
                1040                1045                1050

 Phe Ser Arg Leu Leu Asp Thr Ile Gly Ile Ser Gln Pro Gln Trp
                1055                1060                1065

 Arg Glu Leu Ser Asp Leu Glu Ser Ala Arg Gln Phe Cys Gln Thr
                1070                1075                1080

 Val Gly Tyr Pro Cys Val Val Arg Pro Ser Tyr Val Leu Ser Gly
                1085                1090                1095

 Ala Ala Met Asn Val Ala Tyr Thr Asp Gly Asp Leu Glu Arg Phe
                1100                1105                1110

 Leu Ser Ser Ala Ala Ala Val Ser Lys Glu His Pro Val Val Ile
                1115                1120                1125

 Ser Lys Phe Ile Gln Glu Ala Lys Glu Ile Asp Val Asp Ala Val
                1130                1135                1140

 Ala Ser Asp Gly Val Val Ala Ala Ile Ala Ile Ser Glu His Val
                1145                1150                1155

 Glu Asn Ala Gly Val His Ser Gly Asp Ala Thr Leu Val Thr Pro
                1160                1165                1170

 Pro Gln Asp Ile Thr Ala Lys Thr Leu Glu Arg Ile Lys Ala Ile
                1175                1180                1185

 Val His Ala Val Gly Gln Glu Leu Gln Val Thr Gly Pro Phe Asn
                1190                1195                1200

 Leu Gln Leu Ile Ala Lys Asp Asp Gln Leu Lys Val Ile Glu Cys
                1205                1210                1215

 Asn Val Arg Val Ser Arg Ser Phe Pro Phe Val Ser Lys Thr Leu
                1220                1225                1230

 Gly Val Asp Leu Val Ala Leu Ala Thr Arg Val Ile Met Gly Glu
                1235                1240                1245

 Glu Val Glu Pro Val Gly Leu Met Thr Gly Ser Gly Val Val Gly
                1250                1255                1260

 Val Lys Val Pro Gln Phe Ser Phe Ser Arg Leu Ala Gly Ala Asp
                1265                1270                1275

 Val Val Leu Gly Val Glu Met Thr Ser Thr Gly Glu Val Ala Gly
                1280                1285                1290

 Phe Gly Glu Ser Arg Cys Glu Ala Tyr Leu Lys Ala Met Leu Ser
                1295                1300                1305

 Thr Gly Phe Lys Ile Pro Lys Lys Asn Ile Leu Leu Thr Ile Gly
                1310                1315                1320

 Ser Tyr Lys Asn Lys Ser Glu Leu Leu Pro Thr Val Arg Leu Leu
                1325                1330                1335

 Glu Ser Leu Gly Tyr Ser Leu Tyr Ala Ser Leu Gly Thr Ala Asp
                1340                1345                1350

 Phe Tyr Thr Glu His Gly Val Lys Val Thr Ala Val Asp Trp His
                1355                1360                1365

 Phe Glu Glu Ala Val Asp Gly Glu Cys Pro Pro Gln Arg Ser Ile
                1370                1375                1380

 Leu Glu Gln Leu Ala Glu Lys Asn Phe Glu Leu Val Ile Asn Leu
                1385                1390                1395

 Ser Met Arg Gly Ala Gly Gly Arg Arg Leu Ser Ser Phe Val Thr
                1400                1405                1410

 Lys Gly Tyr Arg Thr Arg Arg Leu Ala Ala Asp Phe Ser Val Pro
                1415                1420                1425

 Leu Ile Ile Asp Ile Lys Cys Thr Lys Leu Phe Val Glu Ala Leu
                1430                1435                1440

 Gly Gln Ile Gly Pro Ala Pro Pro Leu Lys Val His Val Asp Cys
                1445                1450                1455

 Met Thr Ser Gln Lys Leu Val Arg Leu Pro Gly Leu Ile Asp Val
                1460                1465                1470

 His Val His Leu Arg Glu Pro Gly Gly Thr His Lys Glu Asp Phe
                1475                1480                1485

 Ala Ser Gly Thr Ala Ala Ala Leu Ala Gly Gly Ile Thr Met Val
                1490                1495                1500

 Cys Ala Met Pro Asn Thr Arg Pro Pro Ile Ile Asp Ala Pro Ala
                1505                1510                1515

 Leu Ala Leu Ala Gln Lys Leu Ala Glu Ala Gly Ala Arg Cys Asp
                1520                1525                1530

 Phe Ala Leu Phe Leu Gly Ala Ser Ser Glu Asn Ala Gly Thr Leu
                1535                1540                1545

 Gly Thr Val Ala Gly Ser Ala Ala Gly Leu Lys Leu Tyr Leu Asn
                1550                1555                1560

 Glu Thr Phe Ser Glu Leu Arg Leu Asp Ser Val Val Gln Trp Met
                1565                1570                1575

 Glu His Phe Glu Thr Trp Pro Ser His Leu Pro Ile Val Ala His
                1580                1585                1590

 Ala Glu Gln Gln Thr Val Ala Ala Val Leu Met Val Ala Gln Leu
                1595                1600                1605

 Thr Gln Arg Ser Val His Ile Cys His Val Ala Arg Lys Glu Glu
                1610                1615                1620

 Ile Leu Leu Ile Lys Ala Ala Lys Ala Arg Gly Leu Pro Val Thr
                1625                1630                1635

 Cys Glu Val Ala Pro His His Leu Phe Leu Ser His Asp Asp Leu
                1640                1645                1650

 Glu Arg Leu Gly Pro Gly Lys Gly Glu Val Arg Pro Glu Leu Gly
                1655                1660                1665

 Ser Arg Gln Asp Val Glu Ala Leu Trp Glu Asn Met Ala Val Ile
                1670                1675                1680

 Asp Cys Phe Ala Ser Asp His Ala Pro His Thr Leu Glu Glu Lys
                1685                1690                1695

 Cys Gly Ser Arg Pro Pro Pro Gly Phe Pro Gly Leu Glu Thr Met
                1700                1705                1710

 Leu Pro Leu Leu Leu Thr Ala Val Ser Glu Gly Arg Leu Ser Leu
                1715                1720                1725

 Asp Asp Leu Leu Gln Arg Leu His His Asn Pro Arg Arg Ile Phe
                1730                1735                1740

 His Leu Pro Pro Gln Glu Asp Thr Tyr Val Glu Val Asp Leu Glu
                1745                1750                1755

 His Glu Trp Thr Ile Pro Ser His Met Pro Phe Ser Lys Ala His
                1760                1765                1770

 Trp Thr Pro Phe Glu Gly Gln Lys Val Lys Gly Thr Val Arg Arg
                1775                1780                1785

 Val Val Leu Arg Gly Glu Val Ala Tyr Ile Asp Gly Gln Val Leu
                1790                1795                1800

 Val Pro Pro Gly Tyr Gly Gln Asp Val Arg Lys Trp Pro Gln Gly
                1805                1810                1815

 Ala Val Pro Gln Leu Pro Pro Ser Ala Pro Ala Thr Ser Glu Met
                1820                1825                1830

 Thr Thr Thr Pro Glu Arg Pro Arg Arg Gly Ile Pro Gly Leu Pro
                1835                1840                1845

 Asp Gly Arg Phe His Leu Pro Pro Arg Ile His Arg Ala Ser Asp
                1850                1855                1860

 Pro Gly Leu Pro Ala Glu Glu Pro Lys Glu Lys Ser Ser Arg Lys
                1865                1870                1875

 Val Ala Glu Pro Glu Leu Met Gly Thr Pro Asp Gly Thr Cys Tyr
                1880                1885                1890

 Pro Pro Pro Pro Val Pro Arg Gln Ala Ser Pro Gln Asn Leu Gly
                1895                1900                1905

 Thr Pro Gly Leu Leu His Pro Gln Thr Ser Pro Leu Leu His Ser
                1910                1915                1920

 Leu Val Gly Gln His Ile Leu Ser Val Gln Gln Phe Thr Lys Asp
                1925                1930                1935

 Gln Met Ser His Leu Phe Asn Val Ala His Thr Leu Arg Met Met
                1940                1945                1950

 Val Gln Lys Glu Arg Ser Leu Asp Ile Leu Lys Gly Lys Val Met
                1955                1960                1965

 Ala Ser Met Phe Tyr Glu Val Ser Thr Arg Thr Ser Ser Ser Phe
                1970                1975                1980

 Ala Ala Ala Met Ala Arg Leu Gly Gly Ala Val Leu Ser Phe Ser
                1985                1990                1995

 Glu Ala Thr Ser Ser
                2000

<210> 687
<211> 5723
<212> DNA
<213> Homo sapien

<400> 687
 gcagccgcca cattcaacag gcagcagcgc agcgggcgcg ccgctgggga 50

 gagcaagcgg cccgcggcgt ccgtccgtcc ttccgtccgc ggccctgtca 100

 gctggagcgc ggcgcaggct ctgccccggc ccggcggctc tggccggccg 150

 tccagtccgt gcggcggacc ccgaggagcc tcgatgtgga tggccccgcg 200

 aagttaagtt ctgggctcgc gcttccactc cgccgcgcct tcctcccagt 250

 ttccgtccgc tcgccgcacc ggcttcgttc ccccaaatct cggaccgtcc 300

 cttcgcgccc cctccccgtc cgcccccagt gctgcgttct ccccctcttg 350

 gctctcctgc ggctggggga ggggcggggg tcaccatggc cgaggcgcct 400

 caggtggtgg agatcgaccc ggacttcgag ccgctgcccc ggccgcgctc 450

 gtgcacctgg ccgctgccca ggccggagtt tagccagtcc aactcggcca 500

 cctccagccc ggcgccgtcg ggcagcgcgg ctgccaaccc cgacgccgcg 550

 gcgggcctgc cctcggcctc ggctgccgct gtcagcgccg acttcatgag 600

 caacctgagc ttgctggagg agagcgagga cttcccgcag gcgcccggct 650

 ccgtggcggc ggcggtggcg gcggcggccg ccgcggccgc caccgggggg 700

 ctgtgcgggg acttccaggg cccggaggcg ggctgcctgc acccagcgcc 750

 accgcagccc ccgccgcccg ggccgctgtc gcagcacccg ccggtgcccc 800

 ccgccgccgc tgggccgctc gcggggcagc cgcgcaagag cagctcgtcc 850

 cgccgcaacg cgtggggcaa cctgtcctac gccgacctca tcaccaaggc 900

 catcgagagc tcggcggaga agcggctcac gctgtcgcag atctacgagt 950

 ggatggtcaa gagcgtgccc tacttcaagg ataagggtga cagcaacagc 1000

 tcggcgggct ggaagaattc aattcgtcat aatctgtccc tacacagcaa 1050

 gttcattcgt gtgcagaatg aaggaactgg aaaaagttct tggtggatgc 1100

 tcaatccaga gggtggcaag agcgggaaat ctcctaggag aagagctgca 1150

 tccatggaca acaacagtaa atttgctaag agccgaagcc gagctgccaa 1200

 gaagaaagca tctctccagt ctggccagga gggtgctggg gacagccctg 1250

 gatcacagtt ttccaaatgg cctgcaagcc ctggctctca cagcaatgat 1300

 gactttgata actggagtac atttcgccct cgaactagct caaatgctag 1350

 tactattagt gggagactct cacccattat gaccgaacag gatgatcttg 1400

 gagaagggga tgtgcattct atggtgtacc cgccatctgc cgcaaagatg 1450

 gcctctactt tacccagtct gtctgagata agcaatcccg aaaacatgga 1500

 aaatcttttg gataatctca accttctctc atcaccaaca tcattaactg 1550

 tttcgaccca gtcctcacct ggcaccatga tgcagcagac gccgtgctac 1600

 tcgtttgcgc caccaaacac cagtttgaat tcacccagcc caaactacca 1650

 aaaatataca tatggccaat ccagcatgag ccctttgccc cagatgccta 1700

 tacaaacact tcaggacaat aagtcgagtt atggaggtat gagtcagtat 1750

 aactgtgcgc ctggactctt gaaggagttg ctgacttctg actctcctcc 1800

 ccataatgac attatgacac cagttgatcc tggggtagcc cagcccaaca 1850

 gccgggttct gggccagaac gtcatgatgg gccctaattc ggtcatgtca 1900

 acctatggca gccaggcatc tcataacaaa atgatgaatc ccagctccca 1950

 tacccaccct ggacatgctc agcagacatc tgcagttaac gggcgtcccc 2000

 tgccccacac ggtaagcacc atgccccaca cctcgggtat gaaccgcctg 2050

 acccaagtga agacacctgt acaagtgcct ctgccccacc ccatgcagat 2100

 gagtgccctg gggggctact cctccgtgag cagctgcaat ggctatggca 2150

 gaatgggcct tctccaccag gagaagctcc caagtgactt ggatggcatg 2200

 ttcattgagc gcttagactg tgacatggaa tccatcattc ggaatgacct 2250

 catggatgga gatacattgg attttaactt tgacaatgtg ttgcccaacc 2300

 aaagcttccc acacagtgtc aagacaacga cacatagctg ggtgtcaggc 2350

 tgagggttag tgagcaggtt acacttaaaa gtacttcaga ttgtctgaca 2400

 gcaggaactg agagaagcag tccaaagatg tctttcacca actccctttt 2450

 agttttcttg gttaaaaaaa aaaacaaaaa aaaaaaccct cctttttttc 2500

 ctttcgtcag acttggcagc aaagacattt ttcctgtaca ggatgtttgc 2550

 ccaatgtgtg caggttatgt gctgctgtag ataaggactg tgccattgga 2600

 aatttcatta caatgaagtg ccaaactcac tacaccatat aattgcagaa 2650

 aagattttca gatcctggtg tgctttcaag ttttgtatat aagcagtaga 2700

 tacagattgt atttgtgtgt gtttttggtt tttctaaata tccaattggt 2750

 ccaaggaaag tttatactct ttttgtaata ctgtgatggg cctcatgtct 2800

 tgataagtta aacttttgtt tgtactacct gttttctgcg gaactgacgg 2850

 atcacaaaga actgaatctc cattctgcat ctccattgaa cagccttgga 2900

 cctgttcacg ttgccacaga attcacatga gaaccaagta gcctgttatc 2950

 aatctgctaa attaatggac ttgttaaact tttggaaaaa aaaagattaa 3000

 atgccagctt tgtacaggtc ttttctattt ttttttgttt attttgttat 3050

 ttgcaaattt gtacaaacat ttaaatggtt ctaatttcca gataaatgat 3100

 ttttgatgtt attgttggga cttaagaaca tttttggaat agatattgaa 3150

 ctgtaataat gttttcttaa aactagagtc tactttgtta catagtcagc 3200

 ttgtaaattt tgtggaacca caggtatttg gggcagcatt cataattttc 3250

 attttgtatt ctaactggat tagtactaat tttatacatg cttaactggt 3300

 ttgtacactt tgggatgcta cttagtgatg tttctgacta atcttaaatc 3350

 attgtaatta gtacttgcat attcaacgtt tcaggccctg gttgggcagg 3400

 aaagtgatgt atagttatgg acactttgcg tttcttattt aggataactt 3450

 aatatgtttt tatgtatgta ttttaaagaa atttcatctg cttctactga 3500

 actatgcgta ctgcatagca tcaagtcttc tctagagacc tctgtagtcc 3550

 tgggaggcct cataatgttt gtagatcaga aaagggagat ctgcatctaa 3600

 agcaatggtc ctttgtcaaa cgagggattt tgatccactt caccattttg 3650

 agttgagctt tagcaaaagt ttcccctcat aattctttgc tcttgtttca 3700

 gtccaggtgg aggttggttt tgtagttctg ccttgaggaa ttatgtcaac 3750

 actcatactt catctcattc tcccttctgc cctgcagatt agattactta 3800

 gcacactgtg gaagtttaag tggaaggagg gaatttaaaa atgggacttg 3850

 agtggtttgt agaatttgtg ttcataagtt cagatgggta gcaaatggaa 3900

 tagaacttac ttaaaaattg gggagattta tttgaaaacc agctgtaagt 3950

 tgtgcattga gattatgtta aaagccttgg cttaagaatt tgaaaatttc 4000

 tttagcctgt agcaacctaa actgtaattc ctatcattat gttttattac 4050

 tttccaatta cctgtaactg acagaccaaa ttaattggct ttgtgtccta 4100

 tttagtccat cagtattttc aagtcatgtg gaaagcccaa agtcatcaca 4150

 atgaagagaa caggtgcaca gcactgttcc tcttgtgttc ttgagaagga 4200

 tctaattttt ctgtatatag cccacatcac acttgctttg tcttgtatgt 4250

 taattgcatc ttcattggct tggtatttcc taaatgttta acaagaacac 4300

 aagtgttcct gataagattt cctacagtaa gccagctgta ttgtaagctt 4350

 cccaccgtga tgatcatttt tttgaagatt cattgaacag ccaccactct 4400

 atcatcctca ttttggggca gtccaagaca tagctggttt tagaaaccca 4450

 agttcctcta agcacagcct cccgggtatg taactgaact tggtgccaaa 4500

 gtacttgtgt actaatttct attactacgt actgtcactt tcctcccgtg 4550

 ccattactgc atcataatac aaggaacctc agagccccca tttgttcatt 4600

 aaagaggcaa ctacagccaa aatcactgtt aaaatcttac tacttcatgg 4650

 agtagctctt aggaaaatat atcttcctcc tgagtctggg taattatacc 4700

 tctcccaagc ccccattgtg tgttgaaatc ctgtcatgaa tccttggtag 4750

 ctctctgaga acagtgaagt ccagggaaag gcatctggtc tgtctggaaa 4800

 gcaaacatta tgtggcctct ggtagttttt ttcctgtaag aatactgact 4850

 ttctggagta atgagtatat atcagttatt gtacatgatt gctttgtgaa 4900

 atgtgcaaat gatatcacct atgcagcctt gtttgattta ttttctctgg 4950

 tttgtactgt tattaaaagc atattgtatt atagagctat tcagatattt 5000

 taaatataaa gatgtattgt ttccgtaata tagacgtatg gaatatattt 5050

 aggtaataga tgtattactt ggaaagttct gctttgacaa actgacaaag 5100

 tctaaatgag cacatgtatc ccagtgagca gtaaatcaat ggaacatccc 5150

 aagaagagga taaggatgct taaaatggaa atcattctcc aacgatatac 5200

 aaattggact tgttcaactg ctggatatat gctaccaata accccagccc 5250

 caacttaaaa ttcttacatt caagctccta agagttctta atttataact 5300

 aattttaaaa gagaagtttc ttttctggtt ttagtttggg aataatcatt 5350

 cattaaaaaa aatgtattgt ggtttatgcg aacagaccaa cctggcatta 5400

 cagttggcct ctccttgagg tgggcacagc ctggcagtgt ggccaggggt 5450

 ggccatgtaa gtcccatcag gacgtagtca tgcctcctgc atttcgctac 5500

 ccgagtttag taacagtgca gattccacgt tcttgttccg atactctgag 5550

 aagtgcctga tgttgatgta cttacagaca caagaacaat ctttgctata 5600

 attgtataaa gccataaatg tacataaatt atgtttaaat ggcttggtgt 5650

 ctttcttttc taattatgca gaataagctc tttattagga attttttgtg 5700

 aagctattaa atacttgagt taa 5723

<210> 688
<211> 655
<212> PRT
<213> Homo sapien

<400> 688
 Met Ala Glu Ala Pro Gln Val Val Glu Ile Asp Pro Asp Phe Glu
   1               5                  10                  15

 Pro Leu Pro Arg Pro Arg Ser Cys Thr Trp Pro Leu Pro Arg Pro
                  20                  25                  30

 Glu Phe Ser Gln Ser Asn Ser Ala Thr Ser Ser Pro Ala Pro Ser
                  35                  40                  45

 Gly Ser Ala Ala Ala Asn Pro Asp Ala Ala Ala Gly Leu Pro Ser
                  50                  55                  60

 Ala Ser Ala Ala Ala Val Ser Ala Asp Phe Met Ser Asn Leu Ser
                  65                  70                  75

 Leu Leu Glu Glu Ser Glu Asp Phe Pro Gln Ala Pro Gly Ser Val
                  80                  85                  90

 Ala Ala Ala Val Ala Ala Ala Ala Ala Ala Ala Ala Thr Gly Gly
                  95                 100                 105

 Leu Cys Gly Asp Phe Gln Gly Pro Glu Ala Gly Cys Leu His Pro
                 110                 115                 120

 Ala Pro Pro Gln Pro Pro Pro Pro Gly Pro Leu Ser Gln His Pro
                 125                 130                 135

 Pro Val Pro Pro Ala Ala Ala Gly Pro Leu Ala Gly Gln Pro Arg
                 140                 145                 150

 Lys Ser Ser Ser Ser Arg Arg Asn Ala Trp Gly Asn Leu Ser Tyr
                 155                 160                 165

 Ala Asp Leu Ile Thr Lys Ala Ile Glu Ser Ser Ala Glu Lys Arg
                 170                 175                 180

 Leu Thr Leu Ser Gln Ile Tyr Glu Trp Met Val Lys Ser Val Pro
                 185                 190                 195

 Tyr Phe Lys Asp Lys Gly Asp Ser Asn Ser Ser Ala Gly Trp Lys
                 200                 205                 210

 Asn Ser Ile Arg His Asn Leu Ser Leu His Ser Lys Phe Ile Arg
                 215                 220                 225

 Val Gln Asn Glu Gly Thr Gly Lys Ser Ser Trp Trp Met Leu Asn
                 230                 235                 240

 Pro Glu Gly Gly Lys Ser Gly Lys Ser Pro Arg Arg Arg Ala Ala
                 245                 250                 255

 Ser Met Asp Asn Asn Ser Lys Phe Ala Lys Ser Arg Ser Arg Ala
                 260                 265                 270

 Ala Lys Lys Lys Ala Ser Leu Gln Ser Gly Gln Glu Gly Ala Gly
                 275                 280                 285

 Asp Ser Pro Gly Ser Gln Phe Ser Lys Trp Pro Ala Ser Pro Gly
                 290                 295                 300

 Ser His Ser Asn Asp Asp Phe Asp Asn Trp Ser Thr Phe Arg Pro
                 305                 310                 315

 Arg Thr Ser Ser Asn Ala Ser Thr Ile Ser Gly Arg Leu Ser Pro
                 320                 325                 330

 Ile Met Thr Glu Gln Asp Asp Leu Gly Glu Gly Asp Val His Ser
                 335                 340                 345

 Met Val Tyr Pro Pro Ser Ala Ala Lys Met Ala Ser Thr Leu Pro
                 350                 355                 360

 Ser Leu Ser Glu Ile Ser Asn Pro Glu Asn Met Glu Asn Leu Leu
                 365                 370                 375

 Asp Asn Leu Asn Leu Leu Ser Ser Pro Thr Ser Leu Thr Val Ser
                 380                 385                 390

 Thr Gln Ser Ser Pro Gly Thr Met Met Gln Gln Thr Pro Cys Tyr
                 395                 400                 405

 Ser Phe Ala Pro Pro Asn Thr Ser Leu Asn Ser Pro Ser Pro Asn
                 410                 415                 420

 Tyr Gln Lys Tyr Thr Tyr Gly Gln Ser Ser Met Ser Pro Leu Pro
                 425                 430                 435

 Gln Met Pro Ile Gln Thr Leu Gln Asp Asn Lys Ser Ser Tyr Gly
                 440                 445                 450

 Gly Met Ser Gln Tyr Asn Cys Ala Pro Gly Leu Leu Lys Glu Leu
                 455                 460                 465

 Leu Thr Ser Asp Ser Pro Pro His Asn Asp Ile Met Thr Pro Val
                 470                 475                 480

 Asp Pro Gly Val Ala Gln Pro Asn Ser Arg Val Leu Gly Gln Asn
                 485                 490                 495

 Val Met Met Gly Pro Asn Ser Val Met Ser Thr Tyr Gly Ser Gln
                 500                 505                 510

 Ala Ser His Asn Lys Met Met Asn Pro Ser Ser His Thr His Pro
                 515                 520                 525

 Gly His Ala Gln Gln Thr Ser Ala Val Asn Gly Arg Pro Leu Pro
                 530                 535                 540

 His Thr Val Ser Thr Met Pro His Thr Ser Gly Met Asn Arg Leu
                 545                 550                 555

 Thr Gln Val Lys Thr Pro Val Gln Val Pro Leu Pro His Pro Met
                 560                 565                 570

 Gln Met Ser Ala Leu Gly Gly Tyr Ser Ser Val Ser Ser Cys Asn
                 575                 580                 585

 Gly Tyr Gly Arg Met Gly Leu Leu His Gln Glu Lys Leu Pro Ser
                 590                 595                 600

 Asp Leu Asp Gly Met Phe Ile Glu Arg Leu Asp Cys Asp Met Glu
                 605                 610                 615

 Ser Ile Ile Arg Asn Asp Leu Met Asp Gly Asp Thr Leu Asp Phe
                 620                 625                 630

 Asn Phe Asp Asn Val Leu Pro Asn Gln Ser Phe Pro His Ser Val
                 635                 640                 645

 Lys Thr Thr Thr His Ser Trp Val Ser Gly
                 650                 655

<210> 689
<211> 2319
<212> DNA
<213> Homo sapien

<400> 689
 cgaccacccg gcctcggcca ataagcgccg ccctctcgcc cccgtgttac 50

 tgggtagaag aaaacaaaaa caaacagagc gagaagggcc agagactctc 100

 cgaggcggcg gcagagacag aagagcgggg tcggggccgg ctgaccagga 150

 acctgggcga gcagcggcgg gggcccgagg gattctgaag gaagatttcc 200

 attaggtaat ttgtttaatc agtgcaagcg aaattaaggg aaaatggatg 250

 tagaaaatga gcagatactg aatgtaaacc ctgcagatcc tgataactta 300

 agtgactctc tcttttccgg tgatgaagaa aatgctggga ctgaggaaat 350

 aaagaatgaa ataaatggaa attggatttc agcatcctcc attaacgaag 400

 ctagaattaa tgccaaggca aaaaggcgac taaggaaaaa ctcatcccgg 450

 gactctggca gaggcgattc ggtcagcgac agtgggagtg acgcccttag 500

 aagtggatta actgtgccaa ccagtccaaa gggaaggttg ctggataggc 550

 gatccagatc tgggaaagga aggggactac caaagaaagg tggtgcagga 600

 ggcaaaggtg tctggggtac acctggacag gtgtatgatg tggaggaggt 650

 ggatgtgaaa gatcctaact atgatgatga ccaggagaac tgtgtttatg 700

 aaactgtagt tttgcctttg gatgaaaggg catttgagaa gactttaaca 750

 ccaatcatac aggaatattt tgagcatgga gatactaatg aagttgcgga 800

 aatgttaaga gatttaaatc ttggtgaaat gaaaagtgga gtaccagtgt 850

 tggcagtatc cttagcattg gaggggaagg ctagtcatag agagatgaca 900

 tctaagcttc tttctgacct ttgtgggaca gtaatgagca caactgatgt 950

 ggaaaaatca tttgataaat tgttgaaaga tctacctgaa ttagcactgg 1000

 atactcctag agcaccacag ttggtgggcc agtttattgc tagagctgtt 1050

 ggagatggaa ttttatgtaa tacctatatt gatagttaca aaggaactgt 1100

 agattgtgtg caggctagag ctgctctgga taaggctacc gtgcttctga 1150

 gtatgtctaa aggtggaaag cgtaaagata gtgtgtgggg ctctggaggt 1200

 gggcagcaat ctgtcaatca ccttgttaaa gagattgata tgctgctgaa 1250

 agaatattta ctctctggag acatatctga agctgaacat tgccttaagg 1300

 aactggaagt acctcatttt caccatgagc ttgtatatga agctattata 1350

 atggttttag agtcaactgg agaaagtaca tttaagatga ttttggattt 1400

 attaaagtcc ctttggaagt cttctaccat tactgtagac caaatgaaaa 1450

 gaggttatga gagaatttac aatgaaattc cggacattaa tctggatgtc 1500

 ccacattcat actctgtgct ggagcggttt gtagaagaat gttttcaggc 1550

 tggaataatt tccaaacaac tcagagatct ttgtccttca aggggcagaa 1600

 agcgttttgt aagcgaagga gatggaggtc gtcttaaacc agagagctac 1650

 tgaatataag aactcttgca gtcttagatg ttataaaaat atatatctga 1700

 attgtaagag ttgttagcac aagttttttt tttttttttt tttaagcact 1750

 tgttttgggt acaaggcatt tctgacattt tataaaccta catttaaggg 1800

 gaatttttaa aggaaatgtt ttttcttttt tttttgtttt tcgagggggc 1850

 aaggagggac agaaaagtaa cctcttctta agtggaatat tctaataagc 1900

 taccttttgt aagtgccatg tttattatct aatcattcca agttttgcat 1950

 tgatgtctga ctgccactcc tttctttcaa ggacagtgtt ttttgtagta 2000

 aaatcactgg tttatacaaa gctttattta gggggtaaag ttaagctgct 2050

 aaaaccccat gttggctgct gctgttgaga tactgtgctt tgggagtaaa 2100

 aaaagaaagt tatttctttg tcttaaagaa tttttaaaaa attagtcatg 2150

 agacttattc atctttccag ggaacatact gattggtctt aaaagactag 2200

 acagttaagt aaaaggtggc tggaacatct atttttctac aaaactggaa 2250

 aaatgaacct ggttctagaa gaatgtacac caaaataaaa catgtgaagc 2300

 agtaaaaaaa aaaaaaaaa 2319

<210> 690
<211> 469
<212> PRT
<213> Homo sapien

<400> 690
 Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp
   1               5                  10                  15

 Pro Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn
                  20                  25                  30

 Ala Gly Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile
                  35                  40                  45

 Ser Ala Ser Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys
                  50                  55                  60

 Arg Arg Leu Arg Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp
                  65                  70                  75

 Ser Val Ser Asp Ser Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr
                  80                  85                  90

 Val Pro Thr Ser Pro Lys Gly Arg Leu Leu Asp Arg Arg Ser Arg
                  95                 100                 105

 Ser Gly Lys Gly Arg Gly Leu Pro Lys Lys Gly Gly Ala Gly Gly
                 110                 115                 120

 Lys Gly Val Trp Gly Thr Pro Gly Gln Val Tyr Asp Val Glu Glu
                 125                 130                 135

 Val Asp Val Lys Asp Pro Asn Tyr Asp Asp Asp Gln Glu Asn Cys
                 140                 145                 150

 Val Tyr Glu Thr Val Val Leu Pro Leu Asp Glu Arg Ala Phe Glu
                 155                 160                 165

 Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe Glu His Gly Asp
                 170                 175                 180

 Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn Leu Gly Glu
                 185                 190                 195

 Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala Leu Glu
                 200                 205                 210

 Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser Asp
                 215                 220                 225

 Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe
                 230                 235                 240

 Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro
                 245                 250                 255

 Arg Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly
                 260                 265                 270

 Asp Gly Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr
                 275                 280                 285

 Val Asp Cys Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val
                 290                 295                 300

 Leu Leu Ser Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp
                 305                 310                 315

 Gly Ser Gly Gly Gly Gln Gln Ser Val Asn His Leu Val Lys Glu
                 320                 325                 330

 Ile Asp Met Leu Leu Lys Glu Tyr Leu Leu Ser Gly Asp Ile Ser
                 335                 340                 345

 Glu Ala Glu His Cys Leu Lys Glu Leu Glu Val Pro His Phe His
                 350                 355                 360

 His Glu Leu Val Tyr Glu Ala Ile Ile Met Val Leu Glu Ser Thr
                 365                 370                 375

 Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu Lys Ser Leu
                 380                 385                 390

 Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg Gly Tyr
                 395                 400                 405

 Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val Pro
                 410                 415                 420

 His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln
                 425                 430                 435

 Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg
                 440                 445                 450

 Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys
                 455                 460                 465

 Pro Glu Ser Tyr


<210> 691
<211> 2403
<212> DNA
<213> Homo sapien

<400> 691
 cgaccacccg gcctcggcca ataagcgccg ccctctcgcc cccgtgttac 50

 tgggtagaag aaaacaaaaa caaacagagc gagaagggcc agagactctc 100

 cgaggcggcg gcagagacag aagagcgggg tcggggccgg ctgaccagga 150

 acctgggcga gcagcggcgg gggcccgagg gattctgaag gaagatttcc 200

 attaggtaat ttgtttaatc agtgcaagcg aaattaaggg aaaatggatg 250

 tagaaaatga gcagatactg aatgtaaacc ctgcagggta ttttccctaa 300

 ttctccatgg tgcttcaata gcatgttatt atcataaaaa tgaacagttt 350

 tgtggaatag atgaccaaat atcctgataa cttaagtgac tctctctttt 400

 ccggtgatga agaaaatgct gggactgagg aaataaagaa tgaaataaat 450

 ggaaattgga tttcagcatc ctccattaac gaagctagaa ttaatgccaa 500

 ggcaaaaagg cgactaagga aaaactcatc ccgggactct ggcagaggcg 550

 attcggtcag cgacagtggg agtgacgccc ttagaagtgg attaactgtg 600

 ccaaccagtc caaagggaag gttgctggat aggcgatcca gatctgggaa 650

 aggaagggga ctaccaaaga aaggtggtgc aggaggcaaa ggtgtctggg 700

 gtacacctgg acaggtgtat gatgtggagg aggtggatgt gaaagatcct 750

 aactatgatg atgaccagga gaactgtgtt tatgaaactg tagttttgcc 800

 tttggatgaa agggcatttg agaagacttt aacaccaatc atacaggaat 850

 attttgagca tggagatact aatgaagttg cggaaatgtt aagagattta 900

 aatcttggtg aaatgaaaag tggagtacca gtgttggcag tatccttagc 950

 attggagggg aaggctagtc atagagagat gacatctaag cttctttctg 1000

 acctttgtgg gacagtaatg agcacaactg atgtggaaaa atcatttgat 1050

 aaattgttga aagatctacc tgaattagca ctggatactc ctagagcacc 1100

 acagttggtg ggccagttta ttgctagagc tgttggagat ggaattttat 1150

 gtaataccta tattgatagt tacaaaggaa ctgtagattg tgtgcaggct 1200

 agagctgctc tggataaggc taccgtgctt ctgagtatgt ctaaaggtgg 1250

 aaagcgtaaa gatagtgtgt ggggctctgg aggtgggcag caatctgtca 1300

 atcaccttgt taaagagatt gatatgctgc tgaaagaata tttactctct 1350

 ggagacatat ctgaagctga acattgcctt aaggaactgg aagtacctca 1400

 ttttcaccat gagcttgtat atgaagctat tataatggtt ttagagtcaa 1450

 ctggagaaag tacatttaag atgattttgg atttattaaa gtccctttgg 1500

 aagtcttcta ccattactgt agaccaaatg aaaagaggtt atgagagaat 1550

 ttacaatgaa attccggaca ttaatctgga tgtcccacat tcatactctg 1600

 tgctggagcg gtttgtagaa gaatgttttc aggctggaat aatttccaaa 1650

 caactcagag atctttgtcc ttcaaggggc agaaagcgtt ttgtaagcga 1700

 aggagatgga ggtcgtctta aaccagagag ctactgaata taagaactct 1750

 tgcagtctta gatgttataa aaatatatat ctgaattgta agagttgtta 1800

 gcacaagttt tttttttttt tttttttaag cacttgtttt gggtacaagg 1850

 catttctgac attttataaa cctacattta aggggaattt ttaaaggaaa 1900

 tgttttttct tttttttttg tttttcgagg gggcaaggag ggacagaaaa 1950

 gtaacctctt cttaagtgga atattctaat aagctacctt ttgtaagtgc 2000

 catgtttatt atctaatcat tccaagtttt gcattgatgt ctgactgcca 2050

 ctcctttctt tcaaggacag tgttttttgt agtaaaatca ctggtttata 2100

 caaagcttta tttagggggt aaagttaagc tgctaaaacc ccatgttggc 2150

 tgctgctgtt gagatactgt gctttgggag taaaaaaaga aagttatttc 2200

 tttgtcttaa agaattttta aaaaattagt catgagactt attcatcttt 2250

 ccagggaaca tactgattgg tcttaaaaga ctagacagtt aagtaaaagg 2300

 tggctggaac atctattttt ctacaaaact ggaaaaatga acctggttct 2350

 agaagaatgt acaccaaaat aaaacatgtg aagcagtaaa aaaaaaaaaa 2400

 aaa 2403

<210> 692
<211> 458
<212> PRT
<213> Homo sapien

<400> 692
 Met Thr Lys Tyr Pro Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly
   1               5                  10                  15

 Asp Glu Glu Asn Ala Gly Thr Glu Glu Ile Lys Asn Glu Ile Asn
                  20                  25                  30

 Gly Asn Trp Ile Ser Ala Ser Ser Ile Asn Glu Ala Arg Ile Asn
                  35                  40                  45

 Ala Lys Ala Lys Arg Arg Leu Arg Lys Asn Ser Ser Arg Asp Ser
                  50                  55                  60

 Gly Arg Gly Asp Ser Val Ser Asp Ser Gly Ser Asp Ala Leu Arg
                  65                  70                  75

 Ser Gly Leu Thr Val Pro Thr Ser Pro Lys Gly Arg Leu Leu Asp
                  80                  85                  90

 Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu Pro Lys Lys Gly
                  95                 100                 105

 Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly Gln Val Tyr
                 110                 115                 120

 Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp Asp Asp
                 125                 130                 135

 Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp Glu
                 140                 145                 150

 Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe
                 155                 160                 165

 Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu
                 170                 175                 180

 Asn Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser
                 185                 190                 195

 Leu Ala Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys
                 200                 205                 210

 Leu Leu Ser Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val
                 215                 220                 225

 Glu Lys Ser Phe Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala
                 230                 235                 240

 Leu Asp Thr Pro Arg Ala Pro Gln Leu Val Gly Gln Phe Ile Ala
                 245                 250                 255

 Arg Ala Val Gly Asp Gly Ile Leu Cys Asn Thr Tyr Ile Asp Ser
                 260                 265                 270

 Tyr Lys Gly Thr Val Asp Cys Val Gln Ala Arg Ala Ala Leu Asp
                 275                 280                 285

 Lys Ala Thr Val Leu Leu Ser Met Ser Lys Gly Gly Lys Arg Lys
                 290                 295                 300

 Asp Ser Val Trp Gly Ser Gly Gly Gly Gln Gln Ser Val Asn His
                 305                 310                 315

 Leu Val Lys Glu Ile Asp Met Leu Leu Lys Glu Tyr Leu Leu Ser
                 320                 325                 330

 Gly Asp Ile Ser Glu Ala Glu His Cys Leu Lys Glu Leu Glu Val
                 335                 340                 345

 Pro His Phe His His Glu Leu Val Tyr Glu Ala Ile Ile Met Val
                 350                 355                 360

 Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu
                 365                 370                 375

 Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met
                 380                 385                 390

 Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn
                 395                 400                 405

 Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu
                 410                 415                 420

 Glu Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu
                 425                 430                 435

 Cys Pro Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly
                 440                 445                 450

 Gly Arg Leu Lys Pro Glu Ser Tyr
                 455

<210> 693
<211> 4535
<212> DNA
<213> Homo sapien

<400> 693
 agcgggtctg cccgccgccg ccactgctgc tgccaccgcc gtcgccgccg 50

 ccgccgccgc cgccactgct gctgccggtg ctaaggagtt cgctggagcc 100

 ctttcctcag acccggcccg gtcttcgcgc ccggactcct ggcgccagcg 150

 ctaggcgcac tcaccgctct gacgggtgca gacgcgggag ttgtcccaga 200

 ctgtggagtg gcgggcacgg ccccagctcc ccttccgttc cctgacccct 250

 tcttgccatc gccccagaca tggggaacgc ggcgaccgcc aagaaaggca 300

 gcgaggtgga gagcgtgaaa gagtttctag ccaaagccaa agaagacttt 350

 ttgaaaaaat gggagaatcc aactcagaat aatgccggac ttgaagattt 400

 tgaaaggaaa aaaacccttg gaacaggttc atttggaaga gtcatgttgg 450

 taaaacacaa agccactgaa cagtattatg ccatgaagat cttagataag 500

 cagaaggttg ttaaactgaa gcaaatagag catactttga atgagaaaag 550

 aatattacag gcagtgaatt ttcctttcct tgttcgactg gagtatgctt 600

 ttaaggataa ttctaattta tacatggtta tggaatatgt ccctgggggt 650

 gaaatgtttt cacatctaag aagaattgga aggttcagtg agccccatgc 700

 acggttctat gcagctcaga tagtgctaac attcgagtac ctcaattcac 750

 tagacatcat ctacagagat ctaaaacctg aaaatctctt aattgaccat 800

 caaggctata tccaggtcac agactttggg tttgccaaaa gagttaaagg 850

 cagaacttgg acattatgtg gaactccaga gtatttggct ccagaaataa 900

 ttctcagcaa gggctacaat aaggcagtgg attggtgggc attaggagtg 950

 ctaatctatg aaatggcagc tggctatccc ccattctttg cagaccaacc 1000

 aattcagatt tatgaaaaga ttgtttctgg aaaggtccga ttcccatcca 1050

 acttcagttc agatctcaag gaccttctac ggaacctgct gcaggtggat 1100

 ttgaccaaga gatttggaaa tctaaagaat ggtgtcagtg atataaaaac 1150

 tcacaagtgg tttgccacga cagattggat tgctatttac cagaggaagg 1200

 ttgaagctcc attcatacca aagtttagag gctctggaga taccagcaac 1250

 tttgatgact atgaagaaga agatatccgt gtctctataa cagaaaaatg 1300

 tgcaaaagaa tttggtgaat tttaaagagg aacaagatga catctgagct 1350

 cacactcagt gtttgcactc tgttgagaga taaggtagag ctgagaccgt 1400

 ccttgttgaa gcagttacct agttccttca ttccaacgac tgagtgaggt 1450

 ctttattgcc atcatcccgt gtgcgcactc tgcatccacc tatgtaacaa 1500

 ggcaccgcta agcaagcatt gtctgtgcca taacacagta ctagaccact 1550

 ttcttacttc tctttgggtt gtctttctcc tctcctatat ccatttcttc 1600

 cttttccaat ttcattggtt ttctctaaac agtgctccat tttattttgt 1650

 tggtgtttca gatgggcagt gttatggcta cgtgatattt gaagggaagg 1700

 ataagtgttg ctttcagtag ttattgccaa tattgttgtt ggtcaatggc 1750

 ttgaagataa actttctaat aattattatt tctttgagta gctcagactt 1800

 ggttttgcca aaactcttgg taatttttga agatagactg tcttatcacc 1850

 aaggaaattt atacaaatta agactaactt tcttggaatt cactattctg 1900

 gcaataaatt ttggtagact aatacagtac agctagaccc agaaatttgg 1950

 aaggctgtag atcagaggtt ctagttccct ttccctcctt ttatatcctc 2000

 ctctccttga gtaatgaagt gaccagcctg tgtagtgtga caaacgtgtc 2050

 tcattcagca ggaaaaacta atgatatgga tcatcaccca gattctctca 2100

 cttggtacca gcatttctgt aggtattaga gaagagttct aagttttcta 2150

 aaccttaact gttccttaag gattttagcc agtattttaa tagaacatga 2200

 ttaatgaaag tgacaaattt taaattttct ctaatagtcc tcatcataaa 2250

 ctttttaaag gaaaataagc aaactaaaaa gaacattggt ttagataaat 2300

 acttatactt tgcaaagtca aaaatggctt gatttttgga aacaatatag 2350

 aggtattcat atttaaatga gggtttacat ttgttttgtt ttgtaaccgt 2400

 taaaaagaag ttgtttccag ctaattattg tggtgtacta tatttgtgag 2450

 cctagggtag gggcactgct gcaacttctg ctttcatccc atgcctcatc 2500

 aatgaggaaa gggaacaaag tgtataaaac tgccacaatt gtattttaat 2550

 tttgaggtat gatattttca gatatttcat aatttctaac ctctgttctc 2600

 tcagtaaaca gaatgtctga tcgatcatgc agatacaatg ttggtatttg 2650

 agaggttagt ttttttccta cacttttttt tgccaactga cttaacaaca 2700

 ttgctgtcag gtggaaattt caagcacttt tgcacattta gttcagtgtt 2750

 tgttgagaat ccatggctta acccacttgt tttgctattt ttttctttgc 2800

 ttttaatttt ccccatctga ttttatctct gcgtttcagt gacctacctt 2850

 aaaacaacac acgagaagag ttaaactggg ttcattttaa tgatcaattt 2900

 acctgcatat aaaatttatt tttaatcaag ctgatcttaa tgtatataat 2950

 cattctattt gctttattat cggtgcaggt aggtcattaa caccacttct 3000

 tttcatctgt accacaccct ggtgaaacct ttgaagacat aaaaaaaacc 3050

 tgtctgagat gttctttcta ccaatctata tgtctttcgg ttatcaagtg 3100

 tttctgcatg gtaatgtcat gtaaatgctg atattgattt cactggtcca 3150

 tctatattta aaacgtgcaa gaaaaaaata aaatactctg ctctagcaag 3200

 ttttgtgtaa caaaggcata tcgtcatgtt aataaattta aaacatcatt 3250

 cgtataaaat attttaattt tcttgtattt catttagacc caagaacatg 3300

 ctgaccaatg tgttctatat gtaaactaca aattctatgg tagctttgtt 3350

 gtatattatt gtaaaattat tttaataagt catggggatg acaatttgat 3400

 tattacaatt tagttttcag taatcaaaaa gatttctatg aattctaaaa 3450

 aatatttttt tctatgaaat tactagtgcc cagctgtaga atctacctta 3500

 ggtagatgat ccctagacat acgttggttt tgagggctat tcagccattc 3550

 cattttactc tctatttaaa ggccgtgagc aagcttgtca tgagcaaata 3600

 tgtcaaggga gtcaatctct gaccaatcaa gtacactaaa ttagaatatt 3650

 tttaaagtat gtaacattcc cagtttcagc cacaatttag ccaagaataa 3700

 gataaaaact tgaataagaa gtaagtagca taaatcagta tttaacctaa 3750

 aattacatat ttgaaacaga agatattatg ttatgctcag taaataatta 3800

 agagatggca ttgtgtaaga aggagcccta gactgaaagt caagacatct 3850

 gaatttcagg ctggaaaact atcagtatga tctcagcctc agttctcttg 3900

 tctgtaagat ggaagaactg gattaggcag tttgtaagat tcctcctaac 3950

 tttcacagtc gatgacaaga ttgtcttttt atctgatatt ttgaagggta 4000

 tattgctttg aagtaagtct caataaggca atatatttta gggcatcttt 4050

 cttcttatct ctgacagtgt tcttaaaatt atttgaatat cataagagcc 4100

 ttggtgtctg tcctaattcc tttctcactc accgatgctg aatacccagt 4150

 tgaatcaaac tgtcaaccta ccaaaaacga tattgtggct tatgggtatt 4200

 gctgtctcat tcttggtata ttcttgtgtt aactgcccat tggcctgaaa 4250

 atactcattg taagcctgaa aaaaaaaatc tttcccactg ttttttctgc 4300

 ttgttgtaag aatcaaatga aataatgtat gtgaaagcac cttgtaaact 4350

 gtaacctatc aatgtaaaat gttaaggtgt gttgttattt cattaattac 4400

 ttctttgttt agaatggaat ttcctatgca ctactgtagc taggaaatgc 4450

 tgaaaacaac tgtgtttttt aattaatcaa taactgcaaa attaaagtac 4500

 cttcaatgga taagacaaca aaaaaaaaaa aaaaa 4535

<210> 694
<211> 351
<212> PRT
<213> Homo sapien

<400> 694
 Met Gly Asn Ala Ala Thr Ala Lys Lys Gly Ser Glu Val Glu Ser
   1               5                  10                  15

 Val Lys Glu Phe Leu Ala Lys Ala Lys Glu Asp Phe Leu Lys Lys
                  20                  25                  30

 Trp Glu Asn Pro Thr Gln Asn Asn Ala Gly Leu Glu Asp Phe Glu
                  35                  40                  45

 Arg Lys Lys Thr Leu Gly Thr Gly Ser Phe Gly Arg Val Met Leu
                  50                  55                  60

 Val Lys His Lys Ala Thr Glu Gln Tyr Tyr Ala Met Lys Ile Leu
                  65                  70                  75

 Asp Lys Gln Lys Val Val Lys Leu Lys Gln Ile Glu His Thr Leu
                  80                  85                  90

 Asn Glu Lys Arg Ile Leu Gln Ala Val Asn Phe Pro Phe Leu Val
                  95                 100                 105

 Arg Leu Glu Tyr Ala Phe Lys Asp Asn Ser Asn Leu Tyr Met Val
                 110                 115                 120

 Met Glu Tyr Val Pro Gly Gly Glu Met Phe Ser His Leu Arg Arg
                 125                 130                 135

 Ile Gly Arg Phe Ser Glu Pro His Ala Arg Phe Tyr Ala Ala Gln
                 140                 145                 150

 Ile Val Leu Thr Phe Glu Tyr Leu Asn Ser Leu Asp Ile Ile Tyr
                 155                 160                 165

 Arg Asp Leu Lys Pro Glu Asn Leu Leu Ile Asp His Gln Gly Tyr
                 170                 175                 180

 Ile Gln Val Thr Asp Phe Gly Phe Ala Lys Arg Val Lys Gly Arg
                 185                 190                 195

 Thr Trp Thr Leu Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Ile
                 200                 205                 210

 Ile Leu Ser Lys Gly Tyr Asn Lys Ala Val Asp Trp Trp Ala Leu
                 215                 220                 225

 Gly Val Leu Ile Tyr Glu Met Ala Ala Gly Tyr Pro Pro Phe Phe
                 230                 235                 240

 Ala Asp Gln Pro Ile Gln Ile Tyr Glu Lys Ile Val Ser Gly Lys
                 245                 250                 255

 Val Arg Phe Pro Ser Asn Phe Ser Ser Asp Leu Lys Asp Leu Leu
                 260                 265                 270

 Arg Asn Leu Leu Gln Val Asp Leu Thr Lys Arg Phe Gly Asn Leu
                 275                 280                 285

 Lys Asn Gly Val Ser Asp Ile Lys Thr His Lys Trp Phe Ala Thr
                 290                 295                 300

 Thr Asp Trp Ile Ala Ile Tyr Gln Arg Lys Val Glu Ala Pro Phe
                 305                 310                 315

 Ile Pro Lys Phe Arg Gly Ser Gly Asp Thr Ser Asn Phe Asp Asp
                 320                 325                 330

 Tyr Glu Glu Glu Asp Ile Arg Val Ser Ile Thr Glu Lys Cys Ala
                 335                 340                 345

 Lys Glu Phe Gly Glu Phe
                 350

<210> 695
<211> 2945
<212> DNA
<213> Homo sapien

<400> 695
 ccagcccccc ttcccttccc tgaccccttc ttgccatcgc cccagacatg 50

 gggaacgcgg cgaccgccaa gaaaggcagc gaggtggaga gcgtgaaaga 100

 gtttctagcc aaagccaaag aagacttttt gaaaaaatgg gagaatccaa 150

 ctcagaataa tgccggactt gaagattttg aaaggaaaaa aacccttgga 200

 acaggttcat ttggaagagt catgttggta aaacacaaag ccactgaaca 250

 gtattatgcc atgaagatct tagataagca gaaggttgtt aaactgaagc 300

 aaatagagca tactttgaat gagaaaagaa tattacaggc agtgaatttt 350

 cctttccttg ttcgactgga gtatgctttt aaggataatt ctaatttata 400

 catggttatg gaatatgtcc ctgggggtga aatgttttca catctaagaa 450

 gaattggaag gttcagtgag ccccatgcac ggttctatgc agctcagata 500

 gtgctaacat tcgagtacct ccattcacta gacctcatct acagagatct 550

 aaaacctgaa aatctcttaa ttgaccatca aggctatatc caggtcacag 600

 actttgggtt tgccaaaaga gttaaaggca gaacttggac attatgtgga 650

 actccagagt atttggctcc agaaataatt ctcagcaagg gctacaataa 700

 ggcagtggat tggtgggcat taggagtgct aatctatgaa atggcagctg 750

 gctatccccc attctttgca gaccaaccaa ttcagattta tgaaaagatt 800

 gtttctggaa aggtccgatt cccatcccac ttcagttcag atctcaagga 850

 ccttctacgg aacctgctgc aggtggattt gaccaagaga tttggaaatc 900

 taaagaatgg tgtcagtgat ataaaaactc acaagtggtt tgccacgaca 950

 gattggattg ctatttacca gaggaaggtt gaagctccat tcataccaaa 1000

 gtttagaggc tctggagata ccagcaactt tgatgactat gaagaagaag 1050

 atatccgtgt ctctataaca gaaaaatgtg caaaagaatt tggtgaattt 1100

 taaagaggaa caagatgaca tctgagctca cactcagtgt ttgcactctg 1150

 ttgagagata aggtagagct gagaccgtcc ttgttgaagc agttacctag 1200

 ttccttcatt ccaacgactg agtgaggtct ttattgccat catccgtgtg 1250

 cgcactctgc atccacctat gtaacaaggc accgctaagc aagcattgtc 1300

 tgtgccataa cacagtacta gaccactttc ttacttctct ttgggttgtc 1350

 tttctcctct cctacatcca tttcttcctt ttcaatttca ttggttttct 1400

 ctaaacagtg ctccatttta ttttgttggt gtttcagatg ggcagtgtta 1450

 tggctacgtg atatttgaag ggaaggataa gtgttgcttt cagtagttat 1500

 tgccaatatt gttgttggtc aatggcttga agataaactt tctaataatt 1550

 attatttctt tgagtagctc agacttggtt ttgccaaaac tcttggtaat 1600

 ttttgaagat agactgtctt atcaccaagg aaatttatac aaattaagac 1650

 taactttctt ggaattcact attctggcaa taaattttgg tagactaata 1700

 cagtacagct agacccagaa atttggaagg ctgtagatca gaggttctag 1750

 ttccctttcc ctccttttat atcctcctct ccttgagtaa tgaagtgacc 1800

 agcctgtgta gtgtgacaaa cgtgtctcat tcagcaggaa aaactaatga 1850

 tatggatcat cacccagatt ctctcacttg gtaccagcat ttctgtaggt 1900

 attagagaag agttctaagt tttctaaacc ttaactgttc cttaaggatt 1950

 ttagccagta ttttaataga acatgattaa tgaaagtgac aaattttaaa 2000

 ttttctctaa tagtcctcat cataaacttt ttaaaggaaa ataagcaaac 2050

 taaaaagaac attggtttag ataaatactt atactttgca aagtcaaaaa 2100

 tggcttgatt tttggaaaca atatagaggt attcatattt aaatgagggt 2150

 ttacatttgt tttgttttgt aaccgttaaa aagaagttgt ttccagctaa 2200

 ttattgtggt gtactatatt tgtgagccta gggtaggggc actgctgcaa 2250

 cttctgcttt catcccatgc ctcatcaatg aggaaaggga acaaagtgta 2300

 taaaacctgc cacaattgta ttttaatttt gaggtatgat attttcagat 2350

 atttcataat ttctaacctc tgttctctca gtaaacagaa tgtctgatcg 2400

 atcatgcaga tacaatgttg gtatttgaga ggttagtttt tttcctacac 2450

 ttttttttgc caactgactt aacaacattg ctgtcaggtg gaaatttcaa 2500

 gcacttttgc acatttagtt cagtgtttgt tgagaatcca tggcttaacc 2550

 cacttgtttt gctatttttt tctttgcttt taattttccc catctgattt 2600

 tatctctgcg tttcagtgac ctaccttaaa acaacacacg agaagagtta 2650

 aactgggttc attttaatga tcaatttacc tgcatataaa atttattttt 2700

 aatcaagctg atcttaatgt atataatcat tctatttgct ttattatcgg 2750

 tgcaggtagg tcattaacac cacttctttt catctgtacc acaccctggt 2800

 gaaacctttg aagacataaa aaaaacctgt ctgagatgtt ctttctacca 2850

 atctatatgt ctttcggtta tcaagtgttt ctgcatggta atgtcatgta 2900

 aatgctgata ttgatttcac tggtccatct atatttaaaa cgtgc 2945

<210> 696
<211> 351
<212> PRT
<213> Homo sapien

<400> 696
 Met Gly Asn Ala Ala Thr Ala Lys Lys Gly Ser Glu Val Glu Ser
   1               5                  10                  15

 Val Lys Glu Phe Leu Ala Lys Ala Lys Glu Asp Phe Leu Lys Lys
                  20                  25                  30

 Trp Glu Asn Pro Thr Gln Asn Asn Ala Gly Leu Glu Asp Phe Glu
                  35                  40                  45

 Arg Lys Lys Thr Leu Gly Thr Gly Ser Phe Gly Arg Val Met Leu
                  50                  55                  60

 Val Lys His Lys Ala Thr Glu Gln Tyr Tyr Ala Met Lys Ile Leu
                  65                  70                  75

 Asp Lys Gln Lys Val Val Lys Leu Lys Gln Ile Glu His Thr Leu
                  80                  85                  90

 Asn Glu Lys Arg Ile Leu Gln Ala Val Asn Phe Pro Phe Leu Val
                  95                 100                 105

 Arg Leu Glu Tyr Ala Phe Lys Asp Asn Ser Asn Leu Tyr Met Val
                 110                 115                 120

 Met Glu Tyr Val Pro Gly Gly Glu Met Phe Ser His Leu Arg Arg
                 125                 130                 135

 Ile Gly Arg Phe Ser Glu Pro His Ala Arg Phe Tyr Ala Ala Gln
                 140                 145                 150

 Ile Val Leu Thr Phe Glu Tyr Leu His Ser Leu Asp Leu Ile Tyr
                 155                 160                 165

 Arg Asp Leu Lys Pro Glu Asn Leu Leu Ile Asp His Gln Gly Tyr
                 170                 175                 180

 Ile Gln Val Thr Asp Phe Gly Phe Ala Lys Arg Val Lys Gly Arg
                 185                 190                 195

 Thr Trp Thr Leu Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Ile
                 200                 205                 210

 Ile Leu Ser Lys Gly Tyr Asn Lys Ala Val Asp Trp Trp Ala Leu
                 215                 220                 225

 Gly Val Leu Ile Tyr Glu Met Ala Ala Gly Tyr Pro Pro Phe Phe
                 230                 235                 240

 Ala Asp Gln Pro Ile Gln Ile Tyr Glu Lys Ile Val Ser Gly Lys
                 245                 250                 255

 Val Arg Phe Pro Ser His Phe Ser Ser Asp Leu Lys Asp Leu Leu
                 260                 265                 270

 Arg Asn Leu Leu Gln Val Asp Leu Thr Lys Arg Phe Gly Asn Leu
                 275                 280                 285

 Lys Asn Gly Val Ser Asp Ile Lys Thr His Lys Trp Phe Ala Thr
                 290                 295                 300

 Thr Asp Trp Ile Ala Ile Tyr Gln Arg Lys Val Glu Ala Pro Phe
                 305                 310                 315

 Ile Pro Lys Phe Arg Gly Ser Gly Asp Thr Ser Asn Phe Asp Asp
                 320                 325                 330

 Tyr Glu Glu Glu Asp Ile Arg Val Ser Ile Thr Glu Lys Cys Ala
                 335                 340                 345

 Lys Glu Phe Gly Glu Phe
                 350

<210> 697
<211> 1633
<212> DNA
<213> Homo sapien

<400> 697
 gtgctgtttg ggctaacagg atctcctctt gcagtctgca gcccaggacg 50

 ctgattccag cagcgcctta ccgcgcagcc cgaagattca ctatggtgaa 100

 aatcgccttc aataccccta ccgccgtgca aaaggaggag gcgcggcaag 150

 acgtggaggc cctcctgagc cgcacggtca gaactcagat actgaccggc 200

 aaggagctcc gagttgccac ccaggaaaaa gagggctcct ctgggagatg 250

 tatgcttact ctcttaggcc tttcattcat cttggcagga cttattgttg 300

 gtggagcctg catttacaag tacttcatgc ccaagagcac catttaccgt 350

 ggagagatgt gcttttttga ttctgaggat cctgcaaatt cccttcgtgg 400

 aggagagcct aacttcctgc ctgtgactga ggaggctgac attcgtgagg 450

 atgacaacat tgcaatcatt gatgtgcctg tccccagttt ctctgatagt 500

 gaccctgcag caattattca tgactttgaa aagggaatga ctgcttacct 550

 ggacttgttg ctggggaact gctatctgat gcccctcaat acttctattg 600

 ttatgcctcc aaaaaatctg gtagagctct ttggcaaact ggcgagtggc 650

 agatatctgc ctcaaactta tgtggttcga gaagacctag ttgctgtgga 700

 ggaaattcgt gatgttagta accttggcat ctttatttac caactttgca 750

 ataacagaaa gtccttccgc cttcgtcgca gagacctctt gctgggtttc 800

 aacaaacgtg ccattgataa atgctggaag attagacact tccccaacga 850

 atttattgtt gagaccaaga tctgtcaaga gtaagaggca acagatagag 900

 tgtccttggt aataagaagt cagagattta caatatgact ttaacattaa 950

 ggtttatggg atactcaaga tatttactca tgcatttact ctattgctta 1000

 tgctttaaaa aaaggaaaaa aaaaaaaact actaaccact gcaagctctt 1050

 gtcaaatttt agtttaattg gcattgcttg ttttttgaaa ctgaaattac 1100

 ctgagtttca ttttttcttt gaatttatag ggtttagatt tctgaaagca 1150

 gcatgaatat atcacctaac atcctgacaa taaattccat ccgttgtttt 1200

 ttttgtttgt ttgttttttc ttttccttta agtaagctct ttattcatct 1250

 tatggtgcag caattttaaa atttgaaata ttttaaattg tttttgaact 1300

 ttttgtgtaa aatatatcag atctcaacat tgttggtttc ttttgttttt 1350

 cattttgtac aactttcttg aatttagaaa ttacatcttt gcagttctgt 1400

 taggtgctct gtaattaacc tgacttatat gtgaacaatt ttcatgagac 1450

 agtcattttt aactaatgca gtgattcttt ctcactacta tctgtattgt 1500

 ggaatgcaca aaattgtgta ggtgctgaat gctgtaagga gtttaggttg 1550

 tatgaattct acaaccctat aataaatttt actctataca aaaaaaaaaa 1600

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1633

<210> 698
<211> 263
<212> PRT
<213> Homo sapien

<400> 698
 Met Val Lys Ile Ala Phe Asn Thr Pro Thr Ala Val Gln Lys Glu
   1               5                  10                  15

 Glu Ala Arg Gln Asp Val Glu Ala Leu Leu Ser Arg Thr Val Arg
                  20                  25                  30

 Thr Gln Ile Leu Thr Gly Lys Glu Leu Arg Val Ala Thr Gln Glu
                  35                  40                  45

 Lys Glu Gly Ser Ser Gly Arg Cys Met Leu Thr Leu Leu Gly Leu
                  50                  55                  60

 Ser Phe Ile Leu Ala Gly Leu Ile Val Gly Gly Ala Cys Ile Tyr
                  65                  70                  75

 Lys Tyr Phe Met Pro Lys Ser Thr Ile Tyr Arg Gly Glu Met Cys
                  80                  85                  90

 Phe Phe Asp Ser Glu Asp Pro Ala Asn Ser Leu Arg Gly Gly Glu
                  95                 100                 105

 Pro Asn Phe Leu Pro Val Thr Glu Glu Ala Asp Ile Arg Glu Asp
                 110                 115                 120

 Asp Asn Ile Ala Ile Ile Asp Val Pro Val Pro Ser Phe Ser Asp
                 125                 130                 135

 Ser Asp Pro Ala Ala Ile Ile His Asp Phe Glu Lys Gly Met Thr
                 140                 145                 150

 Ala Tyr Leu Asp Leu Leu Leu Gly Asn Cys Tyr Leu Met Pro Leu
                 155                 160                 165

 Asn Thr Ser Ile Val Met Pro Pro Lys Asn Leu Val Glu Leu Phe
                 170                 175                 180

 Gly Lys Leu Ala Ser Gly Arg Tyr Leu Pro Gln Thr Tyr Val Val
                 185                 190                 195

 Arg Glu Asp Leu Val Ala Val Glu Glu Ile Arg Asp Val Ser Asn
                 200                 205                 210

 Leu Gly Ile Phe Ile Tyr Gln Leu Cys Asn Asn Arg Lys Ser Phe
                 215                 220                 225

 Arg Leu Arg Arg Arg Asp Leu Leu Leu Gly Phe Asn Lys Arg Ala
                 230                 235                 240

 Ile Asp Lys Cys Trp Lys Ile Arg His Phe Pro Asn Glu Phe Ile
                 245                 250                 255

 Val Glu Thr Lys Ile Cys Gln Glu
                 260

<210> 699
<211> 1082
<212> DNA
<213> Homo sapien

<400> 699
 gatcccagac ctcggcttgc agtagtgtta gactgaagat aaagtaagtg 50

 ctgtttgggc taacaggatc tcctcttgca gtctgcagcc caggacgctg 100

 attccagcag cgccttaccg cgcagcccga agattcacta tggtgaaaat 150

 cgccttcaat acccctaccg ccgtgcaaaa ggaggaggcg cggcaagacg 200

 tggaggccct cctgagccgc acggtcagaa ctcagatact gaccggcaag 250

 gagctccgag ttgccaccca ggaaaaagag ggctcctctg ggagatgtat 300

 gcttactctc ttaggccttt cattcatctt ggcaggactt attgttggtg 350

 gagcctgcat ttacaagtac ttcatgccca agagcaccat ttaccgtgga 400

 gagatgtgct tttttgattc tgaggatcct gcaaattccc ttcgtggagg 450

 agagcctaac ttcctgcctg tgactgagga ggctgacatt cgtgaggatg 500

 acaacattgc aatcattgat gtgcctgtcc ccagtttctc tgatagtgac 550

 cctgcagcaa ttattcatga ctttgaaaag ggaatgactg cttacctgga 600

 cttgttgctg gggaactgct atctgatgcc cctcaatact tctattgtta 650

 tgcctccaaa aaatctggta gagctctttg gcaaactggc gagtggcaga 700

 tatctgcctc aaacttatgt ggttcgagaa gacctagttg ctgtggagga 750

 aattcgtgat gttagtaacc ttggcatctt tatttaccaa ctttgcaata 800

 acagaaagtc cttccgcctt cgtcgcagag acctcttgct gggtttcaac 850

 aaacgtgcca ttgataaatg ctggaagatt agacacttcc ccaacgaatt 900

 tattgttgag accaagatct gtcaagagta agaggcaaca gatagagtgt 950

 ccttggtaat aagaagtcag agatttacaa tatgacttta acattaaggt 1000

 ttatgggata ctcaagatat ttactcatgc atttactcta ttgcttatgc 1050

 cgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1082

<210> 700
<211> 263
<212> PRT
<213> Homo sapien

<400> 700
 Met Val Lys Ile Ala Phe Asn Thr Pro Thr Ala Val Gln Lys Glu
   1               5                  10                  15

 Glu Ala Arg Gln Asp Val Glu Ala Leu Leu Ser Arg Thr Val Arg
                  20                  25                  30

 Thr Gln Ile Leu Thr Gly Lys Glu Leu Arg Val Ala Thr Gln Glu
                  35                  40                  45

 Lys Glu Gly Ser Ser Gly Arg Cys Met Leu Thr Leu Leu Gly Leu
                  50                  55                  60

 Ser Phe Ile Leu Ala Gly Leu Ile Val Gly Gly Ala Cys Ile Tyr
                  65                  70                  75

 Lys Tyr Phe Met Pro Lys Ser Thr Ile Tyr Arg Gly Glu Met Cys
                  80                  85                  90

 Phe Phe Asp Ser Glu Asp Pro Ala Asn Ser Leu Arg Gly Gly Glu
                  95                 100                 105

 Pro Asn Phe Leu Pro Val Thr Glu Glu Ala Asp Ile Arg Glu Asp
                 110                 115                 120

 Asp Asn Ile Ala Ile Ile Asp Val Pro Val Pro Ser Phe Ser Asp
                 125                 130                 135

 Ser Asp Pro Ala Ala Ile Ile His Asp Phe Glu Lys Gly Met Thr
                 140                 145                 150

 Ala Tyr Leu Asp Leu Leu Leu Gly Asn Cys Tyr Leu Met Pro Leu
                 155                 160                 165

 Asn Thr Ser Ile Val Met Pro Pro Lys Asn Leu Val Glu Leu Phe
                 170                 175                 180

 Gly Lys Leu Ala Ser Gly Arg Tyr Leu Pro Gln Thr Tyr Val Val
                 185                 190                 195

 Arg Glu Asp Leu Val Ala Val Glu Glu Ile Arg Asp Val Ser Asn
                 200                 205                 210

 Leu Gly Ile Phe Ile Tyr Gln Leu Cys Asn Asn Arg Lys Ser Phe
                 215                 220                 225

 Arg Leu Arg Arg Arg Asp Leu Leu Leu Gly Phe Asn Lys Arg Ala
                 230                 235                 240

 Ile Asp Lys Cys Trp Lys Ile Arg His Phe Pro Asn Glu Phe Ile
                 245                 250                 255

 Val Glu Thr Lys Ile Cys Gln Glu
                 260

<210> 701
<211> 1358
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 852
<223> Unknown base

<400> 701
 tgagctgccg tagcggaccc agcacagcca ggagcgtccg ggatgagctc 50

 agccgcggcc gaccactggg cgtggttgct ggtgctcagc ttcgtgtttg 100

 gatgcaatgt tcttaggatc ctcctcccgt ccatctcatc cttcatgtcc 150

 agggtgctgc agaaggacgc ggagcaggag tcacagatga gagcggagat 200

 ccaggacatg aagcaggagc tctccacagt caacatgatg gacgagtttg 250

 ccagatatgc caggctggaa agaaagatca acaagatgac ggataagctc 300

 aaaacccatg tgaaagctcg gacagctcaa ttagccaaga taaaatgggt 350

 gataagtgtc gctttctacg tattgcaggc tgccctgatg atctcactca 400

 tttggaagta ttattctgtc cctgtggctg tcgtgccgag taaatggata 450

 acccctctag accgcctggt agcctttcct actagagtag caggtggtgt 500

 tggaattacc tgttggattt tagtctgtaa caaagttgtc gctattgtgc 550

 ttcatccgtt cagctgaaca ggaggatgga tacagccgcg aggctaaaaa 600

 acggatttcc tcttcctagc ttaaaatctg atttacactg ttttgttttt 650

 taagaaacaa aagtgcatag tttagatttt ttttttgttg aatatgtttg 700

 ttcttggact ttatgagata gtcttataag aatcacgatt ttctacacct 750

 gtcattgagc caagaaagtc cagtttatga cacgtatgta ctagtgaaca 800

 ccgtcctcga tctgtcgaaa tgtgaaatgt ttagggacat ctccatgctg 850

 tnacttgtga tttgccctct tatgtatttt ggtcatattg ccaactggaa 900

 agtcaaaatt ttaacaactt taagtaagtt ctttgaagac ttagtgctgt 950

 ttttaatcca gttagaaagt aacttaattt taataccgct actaaaaatt 1000

 cgaaaatttc ttctttaatc acattcaata tggttaaaag aacaacacta 1050

 attgacattg cgtgggcttt ttctcccttt gtttaaaatg tcatttgttg 1100

 agcaagagtt gtatagtatt atctacttac ttgaaggctg ttaatttttc 1150

 attacagtgt tttgtaaatg tatccacgag accatgatgt cattgttttg 1200

 tgctcaactt gtgttttgta tttaaagcat tttgaatgaa gtgtatttta 1250

 taagcattta atatttatgc tctttagaat ggaacacaga aaacaaacct 1300

 tataagcctg attaaattaa tctgaaccaa aaaaaaaaaa aaaaaaaaaa 1350

 aaaaaaaa 1358

<210> 702
<211> 174
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 852
<223> Unknown amino acid

<400> 702
 Met Ser Ser Ala Ala Ala Asp His Trp Ala Trp Leu Leu Val Leu
   1               5                  10                  15

 Ser Phe Val Phe Gly Cys Asn Val Leu Arg Ile Leu Leu Pro Ser
                  20                  25                  30

 Ile Ser Ser Phe Met Ser Arg Val Leu Gln Lys Asp Ala Glu Gln
                  35                  40                  45

 Glu Ser Gln Met Arg Ala Glu Ile Gln Asp Met Lys Gln Glu Leu
                  50                  55                  60

 Ser Thr Val Asn Met Met Asp Glu Phe Ala Arg Tyr Ala Arg Leu
                  65                  70                  75

 Glu Arg Lys Ile Asn Lys Met Thr Asp Lys Leu Lys Thr His Val
                  80                  85                  90

 Lys Ala Arg Thr Ala Gln Leu Ala Lys Ile Lys Trp Val Ile Ser
                  95                 100                 105

 Val Ala Phe Tyr Val Leu Gln Ala Ala Leu Met Ile Ser Leu Ile
                 110                 115                 120

 Trp Lys Tyr Tyr Ser Val Pro Val Ala Val Val Pro Ser Lys Trp
                 125                 130                 135

 Ile Thr Pro Leu Asp Arg Leu Val Ala Phe Pro Thr Arg Val Ala
                 140                 145                 150

 Gly Gly Val Gly Ile Thr Cys Trp Ile Leu Val Cys Asn Lys Val
                 155                 160                 165

 Val Ala Ile Val Leu His Pro Phe Ser
                 170

<210> 703
<211> 7522
<212> DNA
<213> Homo sapien

<400> 703
 cccgggcgag cccgccgtgc gcacagctct gcccgccgcc cctggagcgg 50

 atccccagcc gtccctgggc gttctcccgg gttctagcaa agccccccgg 100

 ggtgcccatc agtttccttg ggtgactaca gcgtgtgttt tttctttcct 150

 ctttcccctg cctgtgtgcc cttctccagg atggcagagg cggaattgca 200

 caaggaaagg ctgcaagcca tagcagaaaa aagaaagagg cagactgaaa 250

 tagaaggcaa gcgacaacag cttgacgagc agatacttct gctgcagcat 300

 tccaagtcca aagtgcttcg ggagaaatgg ctgctgcagg gcatacccgc 350

 tggaactgcc gaagaggagg aagccaggag gcggcagtct gaagaggatg 400

 agttcagagt caagcaactt gaagataaca ttcagaggct ggagcaagaa 450

 atacaaacgc tagaaagtga agagtcccag atatctgcca aagagcaaat 500

 catcctagag aaactgaagg aaacagaaaa atccttcaag gactttcaga 550

 agggtttctc cagtacggat ggagatgcag taaattacat ttcctcccag 600

 cttcccgacc tgccaatcct ctgttcacga acagcagaac catcacctgg 650

 gcaggacggg accagcagag cggctggagt cgggtgggag aatgtgctgc 700

 taaaggaagg tgagtcagcc tcgaacgcca cagaaacatc cggcccagac 750

 atgactatca agaagcctcc ccagctttct gaggatgata tctggctaaa 800

 aagcgaggga gacaactata gtgccaccct cctggagcct gctgccagct 850

 ctctttcccc agatcacaaa aacatggaaa ttgaggtgtc tgttgcagaa 900

 tgtaaaagtg ttcctggaat cacctctacc ccacatccca tggaccatcc 950

 ctccgctttc tattcacccc cgcataatgg cctccttact gatcaccacg 1000

 aatccctgga taatgatgtt gccagagaga tccgctatct agatgaggtg 1050

 ctagaggcca actgctgtga ttctgctgtg gatggaacgt acaatggaac 1100

 atcctcccca gagcctggtg cagtggttct ggtgggcggc ctaagccccc 1150

 ctgtccacga ggcgacccag ccagaaccca ctgaaagaac agctagccgg 1200

 caggcacctc ctcacatcga gctcagtaat agcagccctg accccatggc 1250

 agaggcagaa agaacaaatg gccattcccc cagccagcct agagatgcgc 1300

 tgggggacag cctgcaggtg cctgtcagcc ccagctccac aaccagctca 1350

 cggtgttctt cccgagatgg agagttcact ctcaccacac tgaaaaagga 1400

 ggccaagttt gagctgcgtg ccttccatga ggacaagaag ccctccaagc 1450

 tctttgagga tgacgagcat gagaaagaac aatactgcat tagaaaagtg 1500

 aggccttcag aggagatgct ggagctggaa aaggagagga gagagctcat 1550

 ccgcagccag gccgtcaaga agaatcctgg cattgcagca aaatggtgga 1600

 atcccccgca ggaaaaaacc atcgaggagc agctggacga ggaacatctg 1650

 gagtcgcaca aaaagtacaa ggagcgcaaa gagagaaggg cacagcagga 1700

 acagttgctg ctgcagaagc agttacagca gcagcagcag cagcccccat 1750

 cgcagctctg cacagcccct gcctcttctc atgaacgcgc aagcatgatt 1800

 gacaaagcaa aggaggacat tgtcacagag cagatagatt tctctgctgc 1850

 tcgcaaacaa tttcagctga tggagaattc caggcaagcg gtggccaagg 1900

 gccagagtac acccaggctg ttctccatca agcctttcta caggcctctg 1950

 gggtcagtca actcagacaa gccactgact aatccgagac caccttctgt 2000

 cgggggacct ccagaagaca gtggtgcctc agccgccaag ggacagaaat 2050

 cccccggtgc cctggagacc ccatcggcag caggaagcca gggcaacaca 2100

 gcctctcagg ggaaggaagg gccctacagc gagccttcta aacgtgggcc 2150

 cttatctaaa ctgtgggctg aggatggaga atttacgagc gcccgggctg 2200

 tcctcactgt ggtcaaggat gatgaccatg ggattttgga tcagttctca 2250

 agatctgtca atgtctcctt gacccaagag gagcttgact ctggtctgga 2300

 cgaattgtcg gtgaggtctc aggataccac agtcctggag accctatcca 2350

 atgatttcag catggacaac atcagtgaca gcggggcatc caatgagaca 2400

 accaatgccc tccaggaaaa ttcactggct gatttttctc tgccccagac 2450

 accacaaact gacaacccct cagagggccg aggagaaggc gtctccaagt 2500

 catttagtga tcatggtttc tattcccctt cctccacgct gggggactct 2550

 ccgttggttg atgacccctt ggagtatcag gctggcctcc tggtgcagaa 2600

 tgccattcaa caagccatag ccgagcaggt ggataaagct gtgtccaaaa 2650

 ccagcaggga tggagcagag caacagggac ctgaagcgac tgtagaggaa 2700

 gctgaagctg cggctttcgg ctcagaaaag cctcagagca tgtttgagcc 2750

 acctcaggtg tcttctcctg ttcaagagaa aagggatgta ttaccaaaga 2800

 ttctgcctgc tgaagacagg gcgctcaggg aaagggggcc cccccagcca 2850

 ctgccagctg tgcagcccag tggcccgatt aacatggagg agaccaggcc 2900

 cgaaggaagc tatttcagca agtactcgga ggcagctgag ctgagaagca 2950

 cagcctccct cctggccact caagaatctg acgtgatggt tgggcctttc 3000

 aagctgaggt ccaggaaaca gcggactttg tccatgattg aggaagagat 3050

 ccgagcagct caggaaaggg aagaggagct gaagaggcag agacaagtct 3100

 tgcagagtac gcagagcccc aggacaaaga atgccccatc actgccctcc 3150

 agaacatgct acaaaactgc tccagggaaa atagagaaag tcaaacctcc 3200

 tccatccccc accactgaag gccccagctt gcagcctgac ttagcccctg 3250

 aagaggctgc cggaacccag cggcccaaga atctgatgca gaccctcatg 3300

 gaagactatg agacacacaa atctaaaagg cgcgagagaa tggatgatag 3350

 tagttacact tctaagttac tgtcttgcaa ggtgacttcc gaggtcctcg 3400

 aggccacacg ggttaatcga agaaagagcg cactggcttt gcgctgggaa 3450

 gcagggatct atgccaacca ggaggaagaa gacaacgaat aaacttcctt 3500

 caacccagga agcgtctttg gtgcttggga gaccaagaaa ccaagaaatt 3550

 aacaactgaa agcattttaa tggactattt attaaagtgc aaacaaactc 3600

 agcaatcctt atgtagacca gaagctgcaa tatacaatga tgaaaatgaa 3650

 acgaaaagga agtcccccca tcagactctg gacacccagg aatcaaaaga 3700

 gaaaggactt ttttggtgac tcaatcccag tgtctggttt ggggccaatc 3750

 tacaatggat ccaaaaggac aaaacatgtt acaagcaaat caacatagtt 3800

 gctgcaggcg gaactgagac cagcctctct gggcgatgaa ggacaatggt 3850

 ggtagggcca cttagagagc agtagggccc aggctggtgc agcctacatg 3900

 gcacaggata tttccctgca ccagtttccc acctgtcact tgcagcatca 3950

 gagggtgttg cattaactcc attttctcca gcagccataa aatgaatggc 4000

 gtttctctcc atatttgccc agaagaggca gttatgattc cacttctcct 4050

 acatttaatt atttttaatt gagaacaact catgatcaca attcataaaa 4100

 tccatatttt aagacaatag ttcttcatgt cacaaacaca atctattcta 4150

 catgaggagg ctgagaaagg ggaagagaaa aacaaaccaa atggatgatg 4200

 ttagctttag gatcgtgtct gcttataata ttcactgatc tgcagtttat 4250

 gagaacacat tttcacagtt atgtttcttc ataggaaaac tatatttagt 4300

 gggcaacaac tatttttatg atgggatggg ggagtatata cacgtataga 4350

 atctgtacgc gttgaacaac ttggttcaag atggtggggg catttttaga 4400

 gcggcaataa ttgaaaaaaa aggcgaactc tgccttggag aggtagatga 4450

 taagaaataa aaaggtgttt ataactattt tgtattataa agtgggcctt 4500

 agagatagga agaagaatga tggattcctt ttggatcaat cagaaaggaa 4550

 acacgaaaga aaagtcagga aggtagagag agaaaaaggg agggaaggag 4600

 aaagaatggg aataaaataa ggaggtaaga gatactattt ttgctgagca 4650

 accagtgtgt ttcaggatga tacaaagaaa aatatagaat agaaataagt 4700

 gcaggcttgg aatcagctac aaatcctaaa gatggggtgt gtgtggatgt 4750

 gtgtgtgtgt gtgtgtacac cattgtgtgt ttgtaaaatg tgtatgttca 4800

 tgagtaaggg tgtgtgtgtg tgtgtattaa aattccagag tgaccgtggc 4850

 acttgggtgt acaggtaatt cctccagagc tgtttgctgg cttcaggagt 4900

 ggagtgagaa tttctttttt atgaaaaggg atataaaggc accgagctga 4950

 tgcagtattt gtaatattaa gttgacctaa caaggtattt gcatgagtca 5000

 caattacaaa gttttgagcg gttttgtaat ttgacattta ggagagtctc 5050

 ctatttattc tcatacttta cattcatgct tagtatacta tagaggatgc 5100

 cagctttaat ctttctgtca tttaaagcaa tatgataagg gtattcaata 5150

 attgggtgcc ctaaatttct ggatgagaaa attttcaatt ctggccatga 5200

 gaaagaaaaa aaaataaaca gccttctttt tttttccttt gttttaaaac 5250

 tgtggttttt taaaaaagca ataattaact cagacctcac taaaaatcat 5300

 ttttgttttt atattgttat gtcataagct ctattatgtt attctaacaa 5350

 gtagcaattt cacaaaattt gtatgtagat gttaacgcac atttcctttg 5400

 cttcttttat tagactagtg ttgactttgg ggggggacat ttattcacaa 5450

 atgagaagta ggcacaaagt aaaaaatgga accatctact aacaaggatc 5500

 ctttaaaact gccaagggag ctctaacttg aagccacatc ctacagatgg 5550

 cagcccaaat agcacatggg caattggcac catctttata tggttgagtc 5600

 tcctgaatat tttgaatgaa ttctcaacaa aatgtgctag ccactgggga 5650

 cgcaaaacaa gtaagatccc tgttgcaaga aattcatttt atagtgaggg 5700

 aggttggcat ggagactaaa attctcagga aaatgagatc cgtgttagat 5750

 tagaagtcct gatgtgaaat gggaggactc aggaaggagg atcgtcttta 5800

 cctgaggatt tctagccaga ggtcccagat gcctgggctg agaacccagc 5850

 gataaggggg cgttcccaaa gcagacacag ggataagaac agaggaggca 5900

 gcagcattgc acagccccag gcacagtggc agttaggatg gctggagagt 5950

 aggatagttc tatgggttgc ccaaaaaatg tgatgcgctt catgttttct 6000

 ctgactcatg gatctggtag agaccataga catgatatag actaacttcc 6050

 ccatttttca caagaggaaa ccatccttat gacttacctt aaagtttttt 6100

 gttctgtttt gaaggaaacc atgtgcttca tgaaacctac agttgacaag 6150

 agaatgtaca gctaagagaa aagcttaaga ggccacacta ttcgcggaat 6200

 ggctttagag gcagatgaag tggtctttga ccacagttga ttgaaccaga 6250

 gcacttattg cttaaagaat aacagagttc tagagctggg ggttcttggg 6300

 ccatgctccg tgtgtggata aggaaagaaa tactgtttct gggactctcc 6350

 cacagtcaca aagctgtttt cactgtggcc cctacatctc ttaacttttg 6400

 ctattactcc tatgctgcct tccggattac tgctgtctat cttcttgctc 6450

 cactcactga agatcctatt ataatcccat gaaaatgtaa attacagttt 6500

 acttgggaga gccagatttt ctctgtgctc ttgagttttt tattcattca 6550

 agaaaccttg ggccaccgct ttgtacatag caccgtgcta ggctctggga 6600

 tcccaaatgg acccttttaa ctttctgaag atgggaccgt cccctggagg 6650

 aaagtcattc ctgcctaatc catcgagaga aagaggctta cgaaaaactt 6700

 tgcctctgat gctcagcccc acccccaaat agcacacaag cttgttaacc 6750

 ccacctctta caaaatgttt agattctgta ggtgttaaaa gcctttctgg 6800

 aagtattgca ttctgccgtg tttataggtg ttcactttcc tccagagctg 6850

 attaactact gacatgactt ggctttctca tccagaaatt atggaaacag 6900

 ggtctgtcag tggcaggagg ccgtgctgtg ttttacttgg atgacacaat 6950

 gcagtttact tgcctcttca tacccatgca tgctgctcac cctagacaat 7000

 gacatataag ccgtatatag atcaatgtcc acatatatat acacacacac 7050

 atatatatat ataaagtgta acaaggaaca ctaaaacagt gttgattctt 7100

 gtctctgaag acaaataatt aaaccttttt tttcccaact aaagaatgga 7150

 tttaattaaa ctatgtattg aaaaaaaagt agcctaagtg ttagagatgg 7200

 tgaatatatt ccattttagt taaagaacaa atttcctgaa ttttaagcat 7250

 tcagtgagct gccaattttg attttgtgtt gctctttacc caaattattt 7300

 tttctttgtt tttctttttt tgggggagga ggggaaaaaa gcagcaatac 7350

 tgtgtttgga aattatactc tgtatctggt tttcctgtgt atgttaacca 7400

 cttaaatgtt attatcctgc tttggtttta gagtgattgt gaggcattca 7450

 atgcaagtat acagttattt tctcattaaa atccaatgtg tgttgagttt 7500

 ttataaaaaa aaaaaaaaaa aa 7522

<210> 704
<211> 1103
<212> PRT
<213> Homo sapien

<400> 704
 Met Ala Glu Ala Glu Leu His Lys Glu Arg Leu Gln Ala Ile Ala
   1               5                  10                  15

 Glu Lys Arg Lys Arg Gln Thr Glu Ile Glu Gly Lys Arg Gln Gln
                  20                  25                  30

 Leu Asp Glu Gln Ile Leu Leu Leu Gln His Ser Lys Ser Lys Val
                  35                  40                  45

 Leu Arg Glu Lys Trp Leu Leu Gln Gly Ile Pro Ala Gly Thr Ala
                  50                  55                  60

 Glu Glu Glu Glu Ala Arg Arg Arg Gln Ser Glu Glu Asp Glu Phe
                  65                  70                  75

 Arg Val Lys Gln Leu Glu Asp Asn Ile Gln Arg Leu Glu Gln Glu
                  80                  85                  90

 Ile Gln Thr Leu Glu Ser Glu Glu Ser Gln Ile Ser Ala Lys Glu
                  95                 100                 105

 Gln Ile Ile Leu Glu Lys Leu Lys Glu Thr Glu Lys Ser Phe Lys
                 110                 115                 120

 Asp Phe Gln Lys Gly Phe Ser Ser Thr Asp Gly Asp Ala Val Asn
                 125                 130                 135

 Tyr Ile Ser Ser Gln Leu Pro Asp Leu Pro Ile Leu Cys Ser Arg
                 140                 145                 150

 Thr Ala Glu Pro Ser Pro Gly Gln Asp Gly Thr Ser Arg Ala Ala
                 155                 160                 165

 Gly Val Gly Trp Glu Asn Val Leu Leu Lys Glu Gly Glu Ser Ala
                 170                 175                 180

 Ser Asn Ala Thr Glu Thr Ser Gly Pro Asp Met Thr Ile Lys Lys
                 185                 190                 195

 Pro Pro Gln Leu Ser Glu Asp Asp Ile Trp Leu Lys Ser Glu Gly
                 200                 205                 210

 Asp Asn Tyr Ser Ala Thr Leu Leu Glu Pro Ala Ala Ser Ser Leu
                 215                 220                 225

 Ser Pro Asp His Lys Asn Met Glu Ile Glu Val Ser Val Ala Glu
                 230                 235                 240

 Cys Lys Ser Val Pro Gly Ile Thr Ser Thr Pro His Pro Met Asp
                 245                 250                 255

 His Pro Ser Ala Phe Tyr Ser Pro Pro His Asn Gly Leu Leu Thr
                 260                 265                 270

 Asp His His Glu Ser Leu Asp Asn Asp Val Ala Arg Glu Ile Arg
                 275                 280                 285

 Tyr Leu Asp Glu Val Leu Glu Ala Asn Cys Cys Asp Ser Ala Val
                 290                 295                 300

 Asp Gly Thr Tyr Asn Gly Thr Ser Ser Pro Glu Pro Gly Ala Val
                 305                 310                 315

 Val Leu Val Gly Gly Leu Ser Pro Pro Val His Glu Ala Thr Gln
                 320                 325                 330

 Pro Glu Pro Thr Glu Arg Thr Ala Ser Arg Gln Ala Pro Pro His
                 335                 340                 345

 Ile Glu Leu Ser Asn Ser Ser Pro Asp Pro Met Ala Glu Ala Glu
                 350                 355                 360

 Arg Thr Asn Gly His Ser Pro Ser Gln Pro Arg Asp Ala Leu Gly
                 365                 370                 375

 Asp Ser Leu Gln Val Pro Val Ser Pro Ser Ser Thr Thr Ser Ser
                 380                 385                 390

 Arg Cys Ser Ser Arg Asp Gly Glu Phe Thr Leu Thr Thr Leu Lys
                 395                 400                 405

 Lys Glu Ala Lys Phe Glu Leu Arg Ala Phe His Glu Asp Lys Lys
                 410                 415                 420

 Pro Ser Lys Leu Phe Glu Asp Asp Glu His Glu Lys Glu Gln Tyr
                 425                 430                 435

 Cys Ile Arg Lys Val Arg Pro Ser Glu Glu Met Leu Glu Leu Glu
                 440                 445                 450

 Lys Glu Arg Arg Glu Leu Ile Arg Ser Gln Ala Val Lys Lys Asn
                 455                 460                 465

 Pro Gly Ile Ala Ala Lys Trp Trp Asn Pro Pro Gln Glu Lys Thr
                 470                 475                 480

 Ile Glu Glu Gln Leu Asp Glu Glu His Leu Glu Ser His Lys Lys
                 485                 490                 495

 Tyr Lys Glu Arg Lys Glu Arg Arg Ala Gln Gln Glu Gln Leu Leu
                 500                 505                 510

 Leu Gln Lys Gln Leu Gln Gln Gln Gln Gln Gln Pro Pro Ser Gln
                 515                 520                 525

 Leu Cys Thr Ala Pro Ala Ser Ser His Glu Arg Ala Ser Met Ile
                 530                 535                 540

 Asp Lys Ala Lys Glu Asp Ile Val Thr Glu Gln Ile Asp Phe Ser
                 545                 550                 555

 Ala Ala Arg Lys Gln Phe Gln Leu Met Glu Asn Ser Arg Gln Ala
                 560                 565                 570

 Val Ala Lys Gly Gln Ser Thr Pro Arg Leu Phe Ser Ile Lys Pro
                 575                 580                 585

 Phe Tyr Arg Pro Leu Gly Ser Val Asn Ser Asp Lys Pro Leu Thr
                 590                 595                 600

 Asn Pro Arg Pro Pro Ser Val Gly Gly Pro Pro Glu Asp Ser Gly
                 605                 610                 615

 Ala Ser Ala Ala Lys Gly Gln Lys Ser Pro Gly Ala Leu Glu Thr
                 620                 625                 630

 Pro Ser Ala Ala Gly Ser Gln Gly Asn Thr Ala Ser Gln Gly Lys
                 635                 640                 645

 Glu Gly Pro Tyr Ser Glu Pro Ser Lys Arg Gly Pro Leu Ser Lys
                 650                 655                 660

 Leu Trp Ala Glu Asp Gly Glu Phe Thr Ser Ala Arg Ala Val Leu
                 665                 670                 675

 Thr Val Val Lys Asp Asp Asp His Gly Ile Leu Asp Gln Phe Ser
                 680                 685                 690

 Arg Ser Val Asn Val Ser Leu Thr Gln Glu Glu Leu Asp Ser Gly
                 695                 700                 705

 Leu Asp Glu Leu Ser Val Arg Ser Gln Asp Thr Thr Val Leu Glu
                 710                 715                 720

 Thr Leu Ser Asn Asp Phe Ser Met Asp Asn Ile Ser Asp Ser Gly
                 725                 730                 735

 Ala Ser Asn Glu Thr Thr Asn Ala Leu Gln Glu Asn Ser Leu Ala
                 740                 745                 750

 Asp Phe Ser Leu Pro Gln Thr Pro Gln Thr Asp Asn Pro Ser Glu
                 755                 760                 765

 Gly Arg Gly Glu Gly Val Ser Lys Ser Phe Ser Asp His Gly Phe
                 770                 775                 780

 Tyr Ser Pro Ser Ser Thr Leu Gly Asp Ser Pro Leu Val Asp Asp
                 785                 790                 795

 Pro Leu Glu Tyr Gln Ala Gly Leu Leu Val Gln Asn Ala Ile Gln
                 800                 805                 810

 Gln Ala Ile Ala Glu Gln Val Asp Lys Ala Val Ser Lys Thr Ser
                 815                 820                 825

 Arg Asp Gly Ala Glu Gln Gln Gly Pro Glu Ala Thr Val Glu Glu
                 830                 835                 840

 Ala Glu Ala Ala Ala Phe Gly Ser Glu Lys Pro Gln Ser Met Phe
                 845                 850                 855

 Glu Pro Pro Gln Val Ser Ser Pro Val Gln Glu Lys Arg Asp Val
                 860                 865                 870

 Leu Pro Lys Ile Leu Pro Ala Glu Asp Arg Ala Leu Arg Glu Arg
                 875                 880                 885

 Gly Pro Pro Gln Pro Leu Pro Ala Val Gln Pro Ser Gly Pro Ile
                 890                 895                 900

 Asn Met Glu Glu Thr Arg Pro Glu Gly Ser Tyr Phe Ser Lys Tyr
                 905                 910                 915

 Ser Glu Ala Ala Glu Leu Arg Ser Thr Ala Ser Leu Leu Ala Thr
                 920                 925                 930

 Gln Glu Ser Asp Val Met Val Gly Pro Phe Lys Leu Arg Ser Arg
                 935                 940                 945

 Lys Gln Arg Thr Leu Ser Met Ile Glu Glu Glu Ile Arg Ala Ala
                 950                 955                 960

 Gln Glu Arg Glu Glu Glu Leu Lys Arg Gln Arg Gln Val Leu Gln
                 965                 970                 975

 Ser Thr Gln Ser Pro Arg Thr Lys Asn Ala Pro Ser Leu Pro Ser
                 980                 985                 990

 Arg Thr Cys Tyr Lys Thr Ala Pro Gly Lys Ile Glu Lys Val Lys
                 995                1000                1005

 Pro Pro Pro Ser Pro Thr Thr Glu Gly Pro Ser Leu Gln Pro Asp
                1010                1015                1020

 Leu Ala Pro Glu Glu Ala Ala Gly Thr Gln Arg Pro Lys Asn Leu
                1025                1030                1035

 Met Gln Thr Leu Met Glu Asp Tyr Glu Thr His Lys Ser Lys Arg
                1040                1045                1050

 Arg Glu Arg Met Asp Asp Ser Ser Tyr Thr Ser Lys Leu Leu Ser
                1055                1060                1065

 Cys Lys Val Thr Ser Glu Val Leu Glu Ala Thr Arg Val Asn Arg
                1070                1075                1080

 Arg Lys Ser Ala Leu Ala Leu Arg Trp Glu Ala Gly Ile Tyr Ala
                1085                1090                1095

 Asn Gln Glu Glu Glu Asp Asn Glu
                1100

<210> 705
<211> 5180
<212> DNA
<213> Homo sapien

<400> 705
 cccgggcgag cccgccgtgc gcacagctct gcccgccgcc cctggagcgg 50

 atccccagcc gtccctgggc gttctcccgg gttctagcaa agccccccgg 100

 ggtgcccatc agtttccttg ggtgactaca gcgtgtgttt tttctttcct 150

 ctttcccctg cctgtgtgcc cttctccagg atggcagagg cggaattgca 200

 caaggaaagg ctgcaagcca tagcagaaaa aagaaagagg cagactgaaa 250

 tagaaggcaa gcgacaacag cttgacgagc agatacttct gctgcagcat 300

 tccaagtcca aagtgcttcg ggagaaatgg ctgctgcagg gcatacccgc 350

 tggaactgcc gaagaggagg aagccaggag gcggcagtct gaagaggatg 400

 agttcagagt caagcaactt gaagataaca ttcagaggct ggagcaagaa 450

 atacaaacgc tagaaagtga agagtcccag atatctgcca aagagcaaat 500

 catcctagag aaactgaagg aaacagaaaa atccttcaag gactttcaga 550

 agggtttctc cagtacggat ggagatgcag taaattacat ttcctcccag 600

 cttcccgacc tgccaatcct ctgttcacga acagcagaac catcacctgg 650

 gcaggacggg accagcagag cggctggagt cgggtgggag aatgtgctgc 700

 taaaggaagg tgagtcagcc tcgaacgcca cagaaacatc cggcccagac 750

 atgactatca agaagcctcc ccagctttct gaggatgata tctggctaaa 800

 aagcgaggga gacaactata gtgccaccct cctggagcct gctgccagct 850

 ctctttcccc agatcacaaa aacatggaaa ttgaggtgtc tgttgcagaa 900

 tgtaaaagtg ttcctggaat cacctctacc ccacatccca tggaccatcc 950

 ctccgctttc tattcacccc cgcataatgg cctccttact gatcaccacg 1000

 aatccctgga taatgatgtt gccagagaga tccgctatct agatgaggtg 1050

 ctagaggcca actgctgtga ttctgctgtg gatggaacgt acaatggaac 1100

 atcctcccca gagcctggtg cagtggttct ggtgggcggc ctaagccccc 1150

 ctgtccacga ggcgacccag ccagaaccca ctgaaagaac agctagccgg 1200

 caggcacctc ctcacatcga gctcagtaat agcagccctg accccatggc 1250

 agaggcagaa agaacaaatg gccattcccc cagccagcct agagatgcgc 1300

 tgggggacag cctgcaggtg cctgtcagcc ccagctccac aaccagctca 1350

 cggtgttctt cccgagatgg agagttcact ctcaccacac tgaaaaagga 1400

 ggccaagttt gagctgcgtg ccttccatga ggacaagaag ccctccaagc 1450

 tctttgagga tgacgagcat gagaaagaac aatactgcat tagaaaagtg 1500

 aggccttcag aggagatgct ggagctggaa aaggagagga gagagctcat 1550

 ccgcagccag gccgtcaaga agaatcctgg cattgcagca aaatggtgga 1600

 atcccccgca ggaaaaaacc atcgaggagc agctggacga ggaacatctg 1650

 gagtcgcaca aaaagtacaa ggagcgcaaa gagagaaggg cacagcagga 1700

 acagttgctg ctgcagaagc agttacagca gcagcagcag cagcccccat 1750

 cgcagctctg cacagcccct gcctcttctc atgaacgcgc aagcatgatt 1800

 gacaaagcaa aggaggacat tgtcacagag cagatagatt tctctgctgc 1850

 tcgcaaacaa tttcagctga tggagaattc caggcaagcg gtggccaagg 1900

 gccagagtac acccaggctg ttctccatca agcctttcta caggcctctg 1950

 gggtcagtca actcagacaa gccactgact aatccgagac caccttctgt 2000

 cgggggacct ccagaagaca gtggtgcctc agccgccaag ggacagaaat 2050

 cccccggtgc cctggagacc ccatcggcag caggaagcca gggcaacaca 2100

 gcctctcagg ggaaggaagg gccctacagc gagccttcta aacgtgggcc 2150

 cttatctaaa ctgtgggctg aggatggaga atttacgagc gcccgggctg 2200

 tcctcactgt ggtcaaggat gatgaccatg ggattttgga tcagttctca 2250

 agatctgtca atgtctcctt gacccaagag gagcttgact ctggtctgga 2300

 cgaattgtcg gtgaggtctc aggataccac agtcctggag accctatcca 2350

 atgatttcag catggacaac atcagtgaca gcggggcatc caatgagaca 2400

 accaatgccc tccaggaaaa ttcactggct gatttttctc tgccccagac 2450

 accacaaact gacaacccct cagagggccg aggagaaggc gtctccaagt 2500

 catttagtga tcatggtttc tattcccctt cctccacgct gggggactct 2550

 ccgttggttg atgacccctt ggagtatcag gctggcctcc tggtgcagaa 2600

 tgccattcaa caagccatag ccgagcaggt ggataaagct gtgtccaaaa 2650

 ccagcaggga tggagcagag caacagggac ctgaagcgac tgtagaggaa 2700

 gctgaagctg cggctttcgg ctcagaaaag cctcagagca tgtttgagcc 2750

 acctcaggtg tcttctcctg ttcaagagaa aagggatgta ttaccaaaga 2800

 ttctgcctgc tgaagacagg gcgctcaggg aaagggggcc cccccagcca 2850

 ctgccagctg tgcagcccag tggcccgatt aacatggagg agaccaggcc 2900

 cgaaggaagc tatttcagca agtactcgga ggcagctgag ctgagaagca 2950

 cagcctccct cctggccact caagaatctg acgtgatggt tgggcctttc 3000

 aagctgaggt ccaggaaaca gcggactttg tccatgattg aggaagagat 3050

 ccgagcagct caggaaaggg aagaggagct gaagaggcag agacaagtct 3100

 tgcagagtac gcagagcccc aggacaaaga atgccccatc actgccctcc 3150

 agaacatgct acaaaactgc tccagggaaa atagagaaag tcaaacctcc 3200

 tccatccccc accactgaag gccccagctt gcagcctgac ttagcccctg 3250

 aagaggctgc cggaacccag cggcccaaga atctgatgca gaccctcatg 3300

 gaagactatg agacacacaa atctaaaagg cgcgagagaa tggatgatag 3350

 tagtgtcctc gaggccacac gggttaatcg aagaaagagc gcactggctt 3400

 tgcgctggga agcagggatc tatgccaacc aggaggaaga agacaacgaa 3450

 taaacttcct tcaacccagg aagcgtcttt ggtgcttggg agaccaagaa 3500

 accaagaaat taacaactga aagcatttta atggactatt tattaaagtg 3550

 caaacaaact cagcaatcct tatgtagacc agaagctgca atatacaatg 3600

 atgaaaatga aacgaaaagg aagtcccccc atcagactct ggacacccag 3650

 gaatcaaaag agaaaggact tttttggtga ctcaatccca gtgtctggtt 3700

 tggggccaat ctacaatgga tccaaaagga caaaacatgt tacaagcaaa 3750

 tcaacatagt tgctgcaggc ggaactgaga ccagcctctc tgggcgatga 3800

 aggacaatgg tggtagggcc acttagagag cagtagggcc caggctggtg 3850

 cagcctacat ggcacaggat atttccctgc accagtttcc cacctgtcac 3900

 ttgcagcatc agagggtgtt gcattaactc cattttctcc agcagccata 3950

 aaatgaatgg cgtttctctc catatttgcc cagaagaggc agttatgatt 4000

 ccacttctcc tacatttaat tatttttaat tgagaacaac tcatgatcac 4050

 aattcataaa atccatattt taagacaata gttcttcatg tcacaaacac 4100

 aatctattct acatgaggag gctgagaaag gggaagagaa aaacaaacca 4150

 aatggatgat gttagcttta ggatcgtgtc tgcttataat attcactgat 4200

 ctgcagttta tgagaacaca ttttcacagt tatgtttctt cataggaaaa 4250

 ctatatttag tgggcaacaa ctatttttat gatgggatgg gggagtatat 4300

 acacgtatag aatctgtacg cgttgaacaa cttggttcaa gatggtgggg 4350

 gcatttttag agcggcaata attgaaaaaa aaggcgaact ctgccttgga 4400

 gaggtagatg ataagaaata aaaaggtgtt tataactatt ttgtattata 4450

 aagtgggcct tagagatagg aagaagaatg atggattcct tttggatcaa 4500

 tcagaaagga aacacgaaag aaaagtcagg aaggtagaga gagaaaaagg 4550

 gagggaagga gaaagaatgg gaataaaata aggaggtaag agatactatt 4600

 tttgctgagc aaccagtgtg tttcaggatg atacaaagaa aaatatagaa 4650

 tagaaataag tgcaggcttg gaatcagcta caaatcctaa agatggggtg 4700

 tgtgtggatg tgtgtgtgtg tgtgtgtaca ccattgtgtg tttgtaaaat 4750

 gtgtatgttc atgagtaagg gtgtgtgtgt gtgtgtatta aaattccaga 4800

 gtgaccgtgg cacttgggtg tacaggtaat tcctccagag ctgtttgctg 4850

 gcttcaggag tggagtgaga atttcttttt tatgaaaagg gatataaagg 4900

 caccgagctg atgcagtatt tgtaatatta agttgaccta acaaggtatt 4950

 tgcatgagtc acaattacaa agttttgagc ggttttgtaa tttgacattt 5000

 aggagagtct cctatttatt ctcatacttt acattcatgc ttagtatact 5050

 atagaggatg ccagctttaa tctttctgtc atttaaagca atatgataag 5100

 ggtattcaat aattgggtgc cctaaatttc tggatgagaa aattttcaat 5150

 tctggccatg agaaaaaaaa aaaaaaaaaa 5180

<210> 706
<211> 1090
<212> PRT
<213> Homo sapien

<400> 706
 Met Ala Glu Ala Glu Leu His Lys Glu Arg Leu Gln Ala Ile Ala
   1               5                  10                  15

 Glu Lys Arg Lys Arg Gln Thr Glu Ile Glu Gly Lys Arg Gln Gln
                  20                  25                  30

 Leu Asp Glu Gln Ile Leu Leu Leu Gln His Ser Lys Ser Lys Val
                  35                  40                  45

 Leu Arg Glu Lys Trp Leu Leu Gln Gly Ile Pro Ala Gly Thr Ala
                  50                  55                  60

 Glu Glu Glu Glu Ala Arg Arg Arg Gln Ser Glu Glu Asp Glu Phe
                  65                  70                  75

 Arg Val Lys Gln Leu Glu Asp Asn Ile Gln Arg Leu Glu Gln Glu
                  80                  85                  90

 Ile Gln Thr Leu Glu Ser Glu Glu Ser Gln Ile Ser Ala Lys Glu
                  95                 100                 105

 Gln Ile Ile Leu Glu Lys Leu Lys Glu Thr Glu Lys Ser Phe Lys
                 110                 115                 120

 Asp Phe Gln Lys Gly Phe Ser Ser Thr Asp Gly Asp Ala Val Asn
                 125                 130                 135

 Tyr Ile Ser Ser Gln Leu Pro Asp Leu Pro Ile Leu Cys Ser Arg
                 140                 145                 150

 Thr Ala Glu Pro Ser Pro Gly Gln Asp Gly Thr Ser Arg Ala Ala
                 155                 160                 165

 Gly Val Gly Trp Glu Asn Val Leu Leu Lys Glu Gly Glu Ser Ala
                 170                 175                 180

 Ser Asn Ala Thr Glu Thr Ser Gly Pro Asp Met Thr Ile Lys Lys
                 185                 190                 195

 Pro Pro Gln Leu Ser Glu Asp Asp Ile Trp Leu Lys Ser Glu Gly
                 200                 205                 210

 Asp Asn Tyr Ser Ala Thr Leu Leu Glu Pro Ala Ala Ser Ser Leu
                 215                 220                 225

 Ser Pro Asp His Lys Asn Met Glu Ile Glu Val Ser Val Ala Glu
                 230                 235                 240

 Cys Lys Ser Val Pro Gly Ile Thr Ser Thr Pro His Pro Met Asp
                 245                 250                 255

 His Pro Ser Ala Phe Tyr Ser Pro Pro His Asn Gly Leu Leu Thr
                 260                 265                 270

 Asp His His Glu Ser Leu Asp Asn Asp Val Ala Arg Glu Ile Arg
                 275                 280                 285

 Tyr Leu Asp Glu Val Leu Glu Ala Asn Cys Cys Asp Ser Ala Val
                 290                 295                 300

 Asp Gly Thr Tyr Asn Gly Thr Ser Ser Pro Glu Pro Gly Ala Val
                 305                 310                 315

 Val Leu Val Gly Gly Leu Ser Pro Pro Val His Glu Ala Thr Gln
                 320                 325                 330

 Pro Glu Pro Thr Glu Arg Thr Ala Ser Arg Gln Ala Pro Pro His
                 335                 340                 345

 Ile Glu Leu Ser Asn Ser Ser Pro Asp Pro Met Ala Glu Ala Glu
                 350                 355                 360

 Arg Thr Asn Gly His Ser Pro Ser Gln Pro Arg Asp Ala Leu Gly
                 365                 370                 375

 Asp Ser Leu Gln Val Pro Val Ser Pro Ser Ser Thr Thr Ser Ser
                 380                 385                 390

 Arg Cys Ser Ser Arg Asp Gly Glu Phe Thr Leu Thr Thr Leu Lys
                 395                 400                 405

 Lys Glu Ala Lys Phe Glu Leu Arg Ala Phe His Glu Asp Lys Lys
                 410                 415                 420

 Pro Ser Lys Leu Phe Glu Asp Asp Glu His Glu Lys Glu Gln Tyr
                 425                 430                 435

 Cys Ile Arg Lys Val Arg Pro Ser Glu Glu Met Leu Glu Leu Glu
                 440                 445                 450

 Lys Glu Arg Arg Glu Leu Ile Arg Ser Gln Ala Val Lys Lys Asn
                 455                 460                 465

 Pro Gly Ile Ala Ala Lys Trp Trp Asn Pro Pro Gln Glu Lys Thr
                 470                 475                 480

 Ile Glu Glu Gln Leu Asp Glu Glu His Leu Glu Ser His Lys Lys
                 485                 490                 495

 Tyr Lys Glu Arg Lys Glu Arg Arg Ala Gln Gln Glu Gln Leu Leu
                 500                 505                 510

 Leu Gln Lys Gln Leu Gln Gln Gln Gln Gln Gln Pro Pro Ser Gln
                 515                 520                 525

 Leu Cys Thr Ala Pro Ala Ser Ser His Glu Arg Ala Ser Met Ile
                 530                 535                 540

 Asp Lys Ala Lys Glu Asp Ile Val Thr Glu Gln Ile Asp Phe Ser
                 545                 550                 555

 Ala Ala Arg Lys Gln Phe Gln Leu Met Glu Asn Ser Arg Gln Ala
                 560                 565                 570

 Val Ala Lys Gly Gln Ser Thr Pro Arg Leu Phe Ser Ile Lys Pro
                 575                 580                 585

 Phe Tyr Arg Pro Leu Gly Ser Val Asn Ser Asp Lys Pro Leu Thr
                 590                 595                 600

 Asn Pro Arg Pro Pro Ser Val Gly Gly Pro Pro Glu Asp Ser Gly
                 605                 610                 615

 Ala Ser Ala Ala Lys Gly Gln Lys Ser Pro Gly Ala Leu Glu Thr
                 620                 625                 630

 Pro Ser Ala Ala Gly Ser Gln Gly Asn Thr Ala Ser Gln Gly Lys
                 635                 640                 645

 Glu Gly Pro Tyr Ser Glu Pro Ser Lys Arg Gly Pro Leu Ser Lys
                 650                 655                 660

 Leu Trp Ala Glu Asp Gly Glu Phe Thr Ser Ala Arg Ala Val Leu
                 665                 670                 675

 Thr Val Val Lys Asp Asp Asp His Gly Ile Leu Asp Gln Phe Ser
                 680                 685                 690

 Arg Ser Val Asn Val Ser Leu Thr Gln Glu Glu Leu Asp Ser Gly
                 695                 700                 705

 Leu Asp Glu Leu Ser Val Arg Ser Gln Asp Thr Thr Val Leu Glu
                 710                 715                 720

 Thr Leu Ser Asn Asp Phe Ser Met Asp Asn Ile Ser Asp Ser Gly
                 725                 730                 735

 Ala Ser Asn Glu Thr Thr Asn Ala Leu Gln Glu Asn Ser Leu Ala
                 740                 745                 750

 Asp Phe Ser Leu Pro Gln Thr Pro Gln Thr Asp Asn Pro Ser Glu
                 755                 760                 765

 Gly Arg Gly Glu Gly Val Ser Lys Ser Phe Ser Asp His Gly Phe
                 770                 775                 780

 Tyr Ser Pro Ser Ser Thr Leu Gly Asp Ser Pro Leu Val Asp Asp
                 785                 790                 795

 Pro Leu Glu Tyr Gln Ala Gly Leu Leu Val Gln Asn Ala Ile Gln
                 800                 805                 810

 Gln Ala Ile Ala Glu Gln Val Asp Lys Ala Val Ser Lys Thr Ser
                 815                 820                 825

 Arg Asp Gly Ala Glu Gln Gln Gly Pro Glu Ala Thr Val Glu Glu
                 830                 835                 840

 Ala Glu Ala Ala Ala Phe Gly Ser Glu Lys Pro Gln Ser Met Phe
                 845                 850                 855

 Glu Pro Pro Gln Val Ser Ser Pro Val Gln Glu Lys Arg Asp Val
                 860                 865                 870

 Leu Pro Lys Ile Leu Pro Ala Glu Asp Arg Ala Leu Arg Glu Arg
                 875                 880                 885

 Gly Pro Pro Gln Pro Leu Pro Ala Val Gln Pro Ser Gly Pro Ile
                 890                 895                 900

 Asn Met Glu Glu Thr Arg Pro Glu Gly Ser Tyr Phe Ser Lys Tyr
                 905                 910                 915

 Ser Glu Ala Ala Glu Leu Arg Ser Thr Ala Ser Leu Leu Ala Thr
                 920                 925                 930

 Gln Glu Ser Asp Val Met Val Gly Pro Phe Lys Leu Arg Ser Arg
                 935                 940                 945

 Lys Gln Arg Thr Leu Ser Met Ile Glu Glu Glu Ile Arg Ala Ala
                 950                 955                 960

 Gln Glu Arg Glu Glu Glu Leu Lys Arg Gln Arg Gln Val Leu Gln
                 965                 970                 975

 Ser Thr Gln Ser Pro Arg Thr Lys Asn Ala Pro Ser Leu Pro Ser
                 980                 985                 990

 Arg Thr Cys Tyr Lys Thr Ala Pro Gly Lys Ile Glu Lys Val Lys
                 995                1000                1005

 Pro Pro Pro Ser Pro Thr Thr Glu Gly Pro Ser Leu Gln Pro Asp
                1010                1015                1020

 Leu Ala Pro Glu Glu Ala Ala Gly Thr Gln Arg Pro Lys Asn Leu
                1025                1030                1035

 Met Gln Thr Leu Met Glu Asp Tyr Glu Thr His Lys Ser Lys Arg
                1040                1045                1050

 Arg Glu Arg Met Asp Asp Ser Ser Val Leu Glu Ala Thr Arg Val
                1055                1060                1065

 Asn Arg Arg Lys Ser Ala Leu Ala Leu Arg Trp Glu Ala Gly Ile
                1070                1075                1080

 Tyr Ala Asn Gln Glu Glu Glu Asp Asn Glu
                1085                1090

<210> 707
<211> 4325
<212> DNA
<213> Homo sapien

<400> 707
 ggaggcgaac tacctgtgcc ctaaccttgg aagctggaga aaagttactg 50

 ctcacaactg acctgaaaac taaagagtct gtgggtagga gaatcagtca 100

 acttcaggac agctggaaag acatggagcc ccagctggca gagatgatta 150

 agcagttcca gagcactgta gagacctggg accagtgtga aaagaaaatc 200

 aaggagttga aaagcaggct gcaagtttta aaggcacaaa gtgaagatcc 250

 tcttccagag cttcacgagg acctccataa cgaaaaagag ctgattaagg 300

 aactagaaca gtctttggct agctggactc agaacttgaa agaacttcaa 350

 actatgaagg cggacttaac ccggcacgtt ctcgtggaag atgtgatggt 400

 tttgaaggag caaatagagc atttgcacag acaatgggag gacctctgct 450

 taagggtggc catacgtaaa caggagattg aagacagact caatacatgg 500

 gttgtattca atgaaaaaaa taaagagttg tgtgcctggc tggtgcagat 550

 ggaaaacaaa gttctacaga cagcggacat tagtattgaa gaaatgattg 600

 aaaagttaca gaaggactgc atggaagaaa taaacttgtt tagtgaaaac 650

 aagttacagt taaagcagat gggtgaccag ttgatcaagg ccagcaacaa 700

 atcaagagca gctgagatcg atgacaagct caacaaaatt aacgatcgtt 750

 ggcaacatct ttttgatgtc atcggatcaa gggtgaagaa gctgaaggag 800

 acctttgctt ttattcagca gttggacaaa aacatgagca accttcgcac 850

 ctggttggct cgaattgagt ctgagctttc caagcctgtt gtttatgatg 900

 tctgcgatga tcaagagatc cagaagaggc tcgctgagca gcaggatcta 950

 cagcgagata ttgaacaaca cagcgcaggg gtggagtccg tgtttaacat 1000

 ctgtgacgtc ctactgcacg actccgatgc ctgtgcaaat gagaccgagt 1050

 gtgactcgat ccagcagacc accaggagcc tggacagacg ctggaggaac 1100

 atttgtgcca tgtccatgga gcggcgcatg aaaatcgagg agacgtggcg 1150

 cctgtggcag aagtttttag acgactattc tcgctttgag gactggctca 1200

 agtcagctga gaggacggca gcctgcccaa attcctcaga ggtgttgtac 1250

 acgagtgcca aagaggaact gaagaggttt gaggcctttc agcggcagat 1300

 tcatgagcgg ctcactcagc tggagctcat caacaagcag taccggcggc 1350

 tggcccggga gaaccgcaca gacacggcca gcaggctgaa gcagatggtc 1400

 cacgagggca accagcgctg ggacaacctt cagaggcggg tcacagccgt 1450

 cctgcggaga ctcaggcatt tcaccaacca gagggaagaa tttgagggca 1500

 ccagggagag cattctggtg tggctcacag agatggacct gcagctgacc 1550

 aacgtggagc acttctcaga gagtgacgcc gatgacaaga tgcgccaact 1600

 gaatggcttc caacaggaaa ttacattaaa taccaacaag attgatcagc 1650

 tcattgtgtt tggggagcag ctgattcaga agagcgagcc cctggatgct 1700

 gtgctgattg aggatgagct ggaggaactc caccgctact gccaggaggt 1750

 gtttggaagg gtctcccggt tccaccggcg gctcacctcc tgcactccgg 1800

 gcttggaaga tgaaaaggag gcctctgaga atgaaacaga catggaagac 1850

 cccagagaaa tccagactga ttcttggcgt aaacggggag agagcgagga 1900

 accgtcatct cctcagtccc tgtgtcatct agtggcccca gggcacgagc 1950

 ggtctggctg cgagacccct gtcagcgtgg actccatccc cctggagtgg 2000

 gaccacacag gcgacgtggg gggctcctcc tctcacgaag aggacgagga 2050

 gggcccatac tacagcgcac tgtcaggtaa atccatttcg gatggccact 2100

 cgtggcatgt tcccgacagc ccttcctgtc ccgagcatca ctacaagcaa 2150

 atggaaggtg acaggaatgt tccacctgtt ccccctgcgt ccagcacccc 2200

 ttataaacca ccctatggaa agctactatt acctccaggc acggatggtg 2250

 gcaaagaagg cccgcgagtc ctgaatggca acccacagca ggaagacggg 2300

 ggactggccg gtatcacaga gcagcagtca ggtgccttcg acagatggga 2350

 gatgattcaa gcacaggagc ttcacaataa gctcaaaata aaacaaaatt 2400

 tgcaacagct gaactctgat atcagcgcca tcactacttg gctgaaaaaa 2450

 actgaagcag agctggaaat gttaaagatg gcaaagcctc cctctgatat 2500

 ccaggaaata gaactgagag tgaagagact gcaggagata ctgaaagcct 2550

 ttgacactta caaggcatta gtggtctctg tcaacgtgag cagcaaggaa 2600

 tttctgcaaa ccgagagccc cgaatccaca gagctccaaa gtagactccg 2650

 ccagctgagc ctgctctggg aagcagcaca gggcgcagtg gacagctgga 2700

 gagggggctt acgacagtcg ctcatgcagt gccaggactt ccaccagttg 2750

 agtcaaaatc tgctgctgtg gttagcgagt gccaagaacc ggaggcagaa 2800

 ggctcatgtc accgatccaa aggcagaccc ccgggctctc ctagagtgtc 2850

 ggagggaact aatgcaactg gaaaaggagc tggtagaacg tcaacctcaa 2900

 gtggacatgt tacaggagat ttcaaacagc cttctcatta agggacatgg 2950

 agaagactgt attgaagctg aagaaaaggt gcatgttatt gagaagaaac 3000

 tcaaacagtt acgggagcaa gtgtcccaag atttaatggc cttgcaggga 3050

 acccagaacc cagcctcacc cctgcccagc ttcgacgagg tagactcggg 3100

 ggaccagcct cctgcaacat ccgtgccagc tccccgagca aagcagttca 3150

 gagcagtgag aactacagaa ggcgaggagg agacagagag cagggtcccc 3200

 ggcagcacac ggccacagcg ctccttcctc tcaagggtgg tccgggcagc 3250

 cctacccctg cagctgctcc tcctgctgct gctgctcctg gcctgcctgc 3300

 tgccctcctc cgaagaagac tacagctgca ctcaggccaa caactttgcc 3350

 cggtcctttt accccatgct gaggtacacc aatgggccac cccccacata 3400

 gagggcatag ctggccacag tgctacacca cctgcctgat tgccaagggt 3450

 gcccagcacg tggccccaga ccaatctgag tgacttagtg ttggcaaggt 3500

 cccgggacct gtgcagactt cttctgggct tacacagcac gggctccctg 3550

 gagcccaggg cagctttcag attgtgttcc tccccaggag cagggaacct 3600

 gtgtggcagg tgccccgggt actttggcag aactagttga ttagtttagg 3650

 gatctctgga aatgtcagtt tcctgaagag ccaagcactt tgtgaattct 3700

 ggtttgtttg taaaacagca ttattataat gtaggtatgg tcaatgagca 3750

 gtggtgtcca tcacatatat tatagaagca agcgagcaca ttccacccta 3800

 gaaatggttc agaaactcat aggcaccctt agctgatgga aacaatcaat 3850

 catatttaat acgcttagaa tcagttttac tccaatcagc tggcaatttt 3900

 gagctgccgg ttatacacca aaatgttctg ttcagtacct agctctgctc 3950

 ttttatattg ctttaaattt ttaaagaaat tatattgcat ggatgtggtt 4000

 atttgtgcat attttttaac aatgcccaat ctgtatgaat aatgtaaact 4050

 tcgatttttt tttaaaaaaa ttagatttta gctggagctt ttgactaatg 4100

 taaagtaaat gccaaactac cgacttgata gggatgtttt tgtaagttaa 4150

 ttttctaaga ctttttcaca tccaaagtga tgctttgctt tgggttttaa 4200

 ctgtttggcc acggcggggg tgggggcggg gggttggtac agaaacttga 4250

 agctgtttgt gatatgtaca actcagatgt ttctcattaa aaaacaaaat 4300

 tagccagaaa aaaaaaaaaa aaaaa 4325

<210> 708
<211> 1092
<212> PRT
<213> Homo sapien

<400> 708
 Met Glu Pro Gln Leu Ala Glu Met Ile Lys Gln Phe Gln Ser Thr
   1               5                  10                  15

 Val Glu Thr Trp Asp Gln Cys Glu Lys Lys Ile Lys Glu Leu Lys
                  20                  25                  30

 Ser Arg Leu Gln Val Leu Lys Ala Gln Ser Glu Asp Pro Leu Pro
                  35                  40                  45

 Glu Leu His Glu Asp Leu His Asn Glu Lys Glu Leu Ile Lys Glu
                  50                  55                  60

 Leu Glu Gln Ser Leu Ala Ser Trp Thr Gln Asn Leu Lys Glu Leu
                  65                  70                  75

 Gln Thr Met Lys Ala Asp Leu Thr Arg His Val Leu Val Glu Asp
                  80                  85                  90

 Val Met Val Leu Lys Glu Gln Ile Glu His Leu His Arg Gln Trp
                  95                 100                 105

 Glu Asp Leu Cys Leu Arg Val Ala Ile Arg Lys Gln Glu Ile Glu
                 110                 115                 120

 Asp Arg Leu Asn Thr Trp Val Val Phe Asn Glu Lys Asn Lys Glu
                 125                 130                 135

 Leu Cys Ala Trp Leu Val Gln Met Glu Asn Lys Val Leu Gln Thr
                 140                 145                 150

 Ala Asp Ile Ser Ile Glu Glu Met Ile Glu Lys Leu Gln Lys Asp
                 155                 160                 165

 Cys Met Glu Glu Ile Asn Leu Phe Ser Glu Asn Lys Leu Gln Leu
                 170                 175                 180

 Lys Gln Met Gly Asp Gln Leu Ile Lys Ala Ser Asn Lys Ser Arg
                 185                 190                 195

 Ala Ala Glu Ile Asp Asp Lys Leu Asn Lys Ile Asn Asp Arg Trp
                 200                 205                 210

 Gln His Leu Phe Asp Val Ile Gly Ser Arg Val Lys Lys Leu Lys
                 215                 220                 225

 Glu Thr Phe Ala Phe Ile Gln Gln Leu Asp Lys Asn Met Ser Asn
                 230                 235                 240

 Leu Arg Thr Trp Leu Ala Arg Ile Glu Ser Glu Leu Ser Lys Pro
                 245                 250                 255

 Val Val Tyr Asp Val Cys Asp Asp Gln Glu Ile Gln Lys Arg Leu
                 260                 265                 270

 Ala Glu Gln Gln Asp Leu Gln Arg Asp Ile Glu Gln His Ser Ala
                 275                 280                 285

 Gly Val Glu Ser Val Phe Asn Ile Cys Asp Val Leu Leu His Asp
                 290                 295                 300

 Ser Asp Ala Cys Ala Asn Glu Thr Glu Cys Asp Ser Ile Gln Gln
                 305                 310                 315

 Thr Thr Arg Ser Leu Asp Arg Arg Trp Arg Asn Ile Cys Ala Met
                 320                 325                 330

 Ser Met Glu Arg Arg Met Lys Ile Glu Glu Thr Trp Arg Leu Trp
                 335                 340                 345

 Gln Lys Phe Leu Asp Asp Tyr Ser Arg Phe Glu Asp Trp Leu Lys
                 350                 355                 360

 Ser Ala Glu Arg Thr Ala Ala Cys Pro Asn Ser Ser Glu Val Leu
                 365                 370                 375

 Tyr Thr Ser Ala Lys Glu Glu Leu Lys Arg Phe Glu Ala Phe Gln
                 380                 385                 390

 Arg Gln Ile His Glu Arg Leu Thr Gln Leu Glu Leu Ile Asn Lys
                 395                 400                 405

 Gln Tyr Arg Arg Leu Ala Arg Glu Asn Arg Thr Asp Thr Ala Ser
                 410                 415                 420

 Arg Leu Lys Gln Met Val His Glu Gly Asn Gln Arg Trp Asp Asn
                 425                 430                 435

 Leu Gln Arg Arg Val Thr Ala Val Leu Arg Arg Leu Arg His Phe
                 440                 445                 450

 Thr Asn Gln Arg Glu Glu Phe Glu Gly Thr Arg Glu Ser Ile Leu
                 455                 460                 465

 Val Trp Leu Thr Glu Met Asp Leu Gln Leu Thr Asn Val Glu His
                 470                 475                 480

 Phe Ser Glu Ser Asp Ala Asp Asp Lys Met Arg Gln Leu Asn Gly
                 485                 490                 495

 Phe Gln Gln Glu Ile Thr Leu Asn Thr Asn Lys Ile Asp Gln Leu
                 500                 505                 510

 Ile Val Phe Gly Glu Gln Leu Ile Gln Lys Ser Glu Pro Leu Asp
                 515                 520                 525

 Ala Val Leu Ile Glu Asp Glu Leu Glu Glu Leu His Arg Tyr Cys
                 530                 535                 540

 Gln Glu Val Phe Gly Arg Val Ser Arg Phe His Arg Arg Leu Thr
                 545                 550                 555

 Ser Cys Thr Pro Gly Leu Glu Asp Glu Lys Glu Ala Ser Glu Asn
                 560                 565                 570

 Glu Thr Asp Met Glu Asp Pro Arg Glu Ile Gln Thr Asp Ser Trp
                 575                 580                 585

 Arg Lys Arg Gly Glu Ser Glu Glu Pro Ser Ser Pro Gln Ser Leu
                 590                 595                 600

 Cys His Leu Val Ala Pro Gly His Glu Arg Ser Gly Cys Glu Thr
                 605                 610                 615

 Pro Val Ser Val Asp Ser Ile Pro Leu Glu Trp Asp His Thr Gly
                 620                 625                 630

 Asp Val Gly Gly Ser Ser Ser His Glu Glu Asp Glu Glu Gly Pro
                 635                 640                 645

 Tyr Tyr Ser Ala Leu Ser Gly Lys Ser Ile Ser Asp Gly His Ser
                 650                 655                 660

 Trp His Val Pro Asp Ser Pro Ser Cys Pro Glu His His Tyr Lys
                 665                 670                 675

 Gln Met Glu Gly Asp Arg Asn Val Pro Pro Val Pro Pro Ala Ser
                 680                 685                 690

 Ser Thr Pro Tyr Lys Pro Pro Tyr Gly Lys Leu Leu Leu Pro Pro
                 695                 700                 705

 Gly Thr Asp Gly Gly Lys Glu Gly Pro Arg Val Leu Asn Gly Asn
                 710                 715                 720

 Pro Gln Gln Glu Asp Gly Gly Leu Ala Gly Ile Thr Glu Gln Gln
                 725                 730                 735

 Ser Gly Ala Phe Asp Arg Trp Glu Met Ile Gln Ala Gln Glu Leu
                 740                 745                 750

 His Asn Lys Leu Lys Ile Lys Gln Asn Leu Gln Gln Leu Asn Ser
                 755                 760                 765

 Asp Ile Ser Ala Ile Thr Thr Trp Leu Lys Lys Thr Glu Ala Glu
                 770                 775                 780

 Leu Glu Met Leu Lys Met Ala Lys Pro Pro Ser Asp Ile Gln Glu
                 785                 790                 795

 Ile Glu Leu Arg Val Lys Arg Leu Gln Glu Ile Leu Lys Ala Phe
                 800                 805                 810

 Asp Thr Tyr Lys Ala Leu Val Val Ser Val Asn Val Ser Ser Lys
                 815                 820                 825

 Glu Phe Leu Gln Thr Glu Ser Pro Glu Ser Thr Glu Leu Gln Ser
                 830                 835                 840

 Arg Leu Arg Gln Leu Ser Leu Leu Trp Glu Ala Ala Gln Gly Ala
                 845                 850                 855

 Val Asp Ser Trp Arg Gly Gly Leu Arg Gln Ser Leu Met Gln Cys
                 860                 865                 870

 Gln Asp Phe His Gln Leu Ser Gln Asn Leu Leu Leu Trp Leu Ala
                 875                 880                 885

 Ser Ala Lys Asn Arg Arg Gln Lys Ala His Val Thr Asp Pro Lys
                 890                 895                 900

 Ala Asp Pro Arg Ala Leu Leu Glu Cys Arg Arg Glu Leu Met Gln
                 905                 910                 915

 Leu Glu Lys Glu Leu Val Glu Arg Gln Pro Gln Val Asp Met Leu
                 920                 925                 930

 Gln Glu Ile Ser Asn Ser Leu Leu Ile Lys Gly His Gly Glu Asp
                 935                 940                 945

 Cys Ile Glu Ala Glu Glu Lys Val His Val Ile Glu Lys Lys Leu
                 950                 955                 960

 Lys Gln Leu Arg Glu Gln Val Ser Gln Asp Leu Met Ala Leu Gln
                 965                 970                 975

 Gly Thr Gln Asn Pro Ala Ser Pro Leu Pro Ser Phe Asp Glu Val
                 980                 985                 990

 Asp Ser Gly Asp Gln Pro Pro Ala Thr Ser Val Pro Ala Pro Arg
                 995                1000                1005

 Ala Lys Gln Phe Arg Ala Val Arg Thr Thr Glu Gly Glu Glu Glu
                1010                1015                1020

 Thr Glu Ser Arg Val Pro Gly Ser Thr Arg Pro Gln Arg Ser Phe
                1025                1030                1035

 Leu Ser Arg Val Val Arg Ala Ala Leu Pro Leu Gln Leu Leu Leu
                1040                1045                1050

 Leu Leu Leu Leu Leu Leu Ala Cys Leu Leu Pro Ser Ser Glu Glu
                1055                1060                1065

 Asp Tyr Ser Cys Thr Gln Ala Asn Asn Phe Ala Arg Ser Phe Tyr
                1070                1075                1080

 Pro Met Leu Arg Tyr Thr Asn Gly Pro Pro Pro Thr
                1085                1090

<210> 709
<211> 5398
<212> DNA
<213> Homo sapien

<400> 709
 cgtgcggcgg tgggctggtc ttccgcggcc ggcgttgcgc cgcggcggag 50

 ggtgggcgcg cggggagcgg gatggagctg gggcgaccct tgctggaggt 100

 actggcctca gccctttctc ccgcttcccc acccctctta cccccagatt 150

 acattctctg tgtggtgtct ttactgcaga tgaaggattt gggggcagag 200

 cacttggcag gtcatgaagg ggtccaactt ctcgggttgt tgaacgtcta 250

 cctggaacaa gaagagagat tccaacctcg agaaaaaggg ctgagtttga 300

 ttgaggctac cccggagaat gataacactt tgtgtccagg attgagaaat 350

 gccaaagttg aagatttaag gagtttagcc aacttttttg gatcttgcac 400

 tgaaactttt gtcctggctg tcaatatttt ggacaggttc ttggctctta 450

 tgaaggtgaa acctaaacat ttgtcttgca ttggagtctg ttcttttttg 500

 ctggctgcta gaatagttga agaagactgc aatattccat ccactcatga 550

 tgtgatccgg attagtcagt gtaaatgtac tgcttctgac ataaaacgga 600

 tggaaaaaat aatttcagaa aaattgcact atgaattgga agctactact 650

 gccttaaact ttttgcactt ataccatact attatacttt gtcatacttc 700

 agaaaggaaa gaaatactga gccttgataa actagaagct cagctgaaag 750

 cttgcaactg ccgactcatc ttttcaaaag caaaaccatc tgtattagcc 800

 ttgtgccttc tcaatttgga agtggaaact ttgaaatctg ttgaattact 850

 ggaaattctc ttgctagtta aaaaacattc caagattaat gacactgagt 900

 tcttctactg gagagagttg gtttctaaat gcctagccga gtattcttct 950

 cctgaatgtt gcaaaccaga tcttaagaag ttggtttgga tcgtttcaag 1000

 gcgcacagcc cagaacctcc acaacagcta ctatagtgtt cctgagctgc 1050

 caacgatacc tgaggggggt tgttttgatg aaagtgaaag tgaggactct 1100

 tgtgaagata tgagttgtgg agaggagagt ctcagcagct ctcctcccag 1150

 tgatcaagag tgcaccttct ttttcaactt caaagtggca caaacactgt 1200

 gctttccatc ttagaaatct gattgttctg tcagaattta tatttacagg 1250

 tttcaaagca ataaatgggg gaataggtag tttcctggtt tagcccccat 1300

 ctagtcagga attaatatac tggaatacct accttctatt tgttattcag 1350

 atcagatctg gcctattttc atatttatcc taagccatca aatggggtag 1400

 tgcctcttaa accattaaca gtactttaga cattggcact ttatttttct 1450

 cgtagatctt tagctacttt ggggaggagg gaaggtgctg ataccttcaa 1500

 tttgttactt ttcaagattt ttaaaaataa ctagtgtagc ttatcttaaa 1550

 cattttataa aaccttcaga tgtctttaag cagattggaa gtatgcaagt 1600

 gcttccttag cagggacagt ggataatcct taatggttta tcatagattt 1650

 caccctcccc ccttctcaga agagtgagta tgctcttaaa tgtcaaacac 1700

 atttttgttg ttttgttttt taaatgatca gtgtctattt gatgtgatgc 1750

 agatcttata aatttgggaa ttataatatt gacatttctg tgatttttat 1800

 atatgtaatg tcttaattga gatttctgtt aaggcagaaa taattaggct 1850

 agggctctta gttttcattc ctattgccca agtattgtca aactatggta 1900

 ttattttaat gttactttaa aaatccataa tctgctagtt ttgcatgtac 1950

 ttatatgaaa acagtgcagt aagttgaaaa ctcagtatct atggaattga 2000

 taaatgttga tctggtgtag tatattttat cgcattttct tatattaaaa 2050

 aatgtctgca tgattacatt ttatttcctt tgtaatttac atttcagaat 2100

 agtgtattgc tatatgggtg ccaagattga atatgaagaa cccgagtgtt 2150

 tgtagtatta tagttttaag caaatctgtg tggtgataca gccataagaa 2200

 tggggcttat ataaactctg tacatgtaag attttgtaca gagaattttt 2250

 aactttataa attgtatatg aacatgtaaa tcttttaaaa tgtacataaa 2300

 atactgtatt tttttacctt gtgtgtgata gtctagtcat tgcatgtaaa 2350

 tataatttat tatgtattct gtagtataaa tcatacattg atgacttaca 2400

 tttttactgg taagtcaaca tccgttggat gttttctgaa gtggctcttt 2450

 ttgaagtgat aatagattgt aattcaaaat aaaattatta atgaattctc 2500

 cttgtttggg atcacatctt aatttttaat ctgttaaaag ttcttgatgt 2550

 attttaatga gaagacttta ggtgaggcta cagtgattcc agagtgagcc 2600

 ttctaactgg ctagcagaag ttctctaggt ttggcatctg tgccttggag 2650

 atactgaaag agaatctgtc atttgacaat tgacctcttt gtgggatgga 2700

 ctcattaagt atgctctcag agactggtat attaccagaa tgcctattaa 2750

 ttttcagtga gaggcaacag gtattaagta gaacagaatg ctcaggttgg 2800

 cagattagaa cgatctttca ggagacaaag caagttttaa tcagttgttt 2850

 ggttaataag tatggggtgt tcgctgtgat agggccccgc cagcttctgg 2900

 ctcttgtgga cctcaaaagt atcaggtggt tttgcaagtg gtggtccttt 2950

 cccctgcccc accccaatag gttccccatc tgtctagttt gatttttgta 3000

 gacctttgtt ttctctagtt agaaaatcag gtacactgaa tatggttttc 3050

 atgtaacacc tcttctctgg agataggggt atgttttcct acccttctag 3100

 tggagaatcc tacttgagga tgacctttcc tctcttacta aataatatta 3150

 gtaaatagtg ggcaatatat tctgctttca gattttgatt tgttgagatg 3200

 taaaagttgt ttggggctta ccaaatctca agactctctt tagctcctgc 3250

 aggattgtat tgcttttctt actggatatt tttcctgggt aagcatcttt 3300

 gtggcttcat ctcttccccc tgtggttttc agtgtattta gtcgagacct 3350

 ctctgctgag cttgcaacct gtttattcac atggcctgcc atgccacttg 3400

 gaggtttctg attactccca aacctgctgg ttctttatgt ctttctcagc 3450

 gaataattcc atctgttcat gttggaaact taggtgatat gctcatctcc 3500

 ttttgcctgt ttatggaggt caccagcctc tatcatttgt atgatttcgt 3550

 ttacactgtt tatatctctc tgtcccccct ttttctgcca ttggcatggt 3600

 ttagacctgt actctttatc agcagaggta ctgtaatata tttgtgatcc 3650

 ctcagcttcc aggcttactc ctggtctctg ccttcctatc tacatatcct 3700

 tttaaaataa aattttaact atctcctgaa aaattgttga gtaggtcacg 3750

 cacaatcagg agaaaaatct attcatgaca tacaagtctc tgtctaatct 3800

 gaacactgca cctgtctctg gccttttttt cttgtcattt cctagacctt 3850

 aaaaaatgtg tattgagaaa gaactctgtt agctatacag aagatgaact 3900

 gggcaatata gagtagcagc atggagacca gtctgactga actaaggcag 3950

 tggaagtgtg gatgaggaag agaggtgaaa attgagaagc gctatccttt 4000

 ctctttgggc attattagga ggctcacaga caagtccagg agtctggtta 4050

 taccctcctg tgccattcaa ccaggtggct ttcccatgac tgtgatgaat 4100

 aaaattgaga agcccctgcc cttttcagag cagagggtga ggagaaagct 4150

 accattttgt cctcatcctt acccccgttg acttggcgag agatttgacc 4200

 tttcaggttt tgatcctgtc attttctagg atgtggtgca cgcactttgc 4250

 tgttgcgcat ggtgaagtat tgtgcctagg tcctgggtct tcatctgttt 4300

 ggctctgcta ctgtttcctc ctcccaggaa gtgtggttag acaaataatg 4350

 tgttttaatt acctgtcaca ctcaggatta atacatactc aggttaactg 4400

 tagagaggca ttggcttcag aacactcctc gtgacaattt taaccatttt 4450

 ctttgtctag agtctgcctt tttctttttt acaatttctt ttatttcaac 4500

 actaggtttc aatatggtgt tcctgctacc tcccacctcc ctcctccctc 4550

 atcacacatg caaattgtca gcttattgag acaacccact tagattcata 4600

 tatggacaag gacaaggtat tttgcatttg ttactggaat tcagttttcc 4650

 taactattta ctaccagaaa tggtcaataa cttactttgt ggttagcaaa 4700

 tcaaattgtg tgatagatag tttcccagta tgatggccag tcagtctttc 4750

 catccctgtg cctacatgct gctcttcccg tccacaagtg gagtctgttt 4800

 ctcttgagtt ttggctggcc ttatgaatgg ctttgcttac tgaagtgcag 4850

 cagaagaaat ttagtatatg tccaagccta ggctttaaga gactggcagc 4900

 tttcctttta tcctttttgg aagctagcca ccatgctgca aagaagctca 4950

 gctggattac tgaaagatga gaggccatgt ggagagagac tcttgaggat 5000

 gagagattat cttggatgtt ccagccttaa gctcccagct gaatgtgggt 5050

 gtatcctcag ctacaccaca gaaaacagag gaactactca gtcgatccca 5100

 atcaacccac agactcacta gaaataacaa attattgttt taagccacga 5150

 ggttttgggg gagggttgtt aaacagtaat agataagtga gacagattgc 5200

 ttgttattta tggtcaaatg gtgattatct ctggtgagat tacaggtgat 5250

 gtttttttta agttatgcct atctgtagtt tccttttttt cctaaaattg 5300

 atttgaatta ttagtgtatt aacagaataa agaatgaact ttaaaacaca 5350

 cacgctggtt atatgcttcc tctaattaaa attcatggct ctcaccac 5398

<210> 710
<211> 403
<212> PRT
<213> Homo sapien

<400> 710
 Cys Gly Gly Gly Leu Val Phe Arg Gly Arg Arg Cys Ala Ala Ala
   1               5                  10                  15

 Glu Gly Gly Arg Ala Gly Ser Gly Met Glu Leu Gly Arg Pro Leu
                  20                  25                  30

 Leu Glu Val Leu Ala Ser Ala Leu Ser Pro Ala Ser Pro Pro Leu
                  35                  40                  45

 Leu Pro Pro Asp Tyr Ile Leu Cys Val Val Ser Leu Leu Gln Met
                  50                  55                  60

 Lys Asp Leu Gly Ala Glu His Leu Ala Gly His Glu Gly Val Gln
                  65                  70                  75

 Leu Leu Gly Leu Leu Asn Val Tyr Leu Glu Gln Glu Glu Arg Phe
                  80                  85                  90

 Gln Pro Arg Glu Lys Gly Leu Ser Leu Ile Glu Ala Thr Pro Glu
                  95                 100                 105

 Asn Asp Asn Thr Leu Cys Pro Gly Leu Arg Asn Ala Lys Val Glu
                 110                 115                 120

 Asp Leu Arg Ser Leu Ala Asn Phe Phe Gly Ser Cys Thr Glu Thr
                 125                 130                 135

 Phe Val Leu Ala Val Asn Ile Leu Asp Arg Phe Leu Ala Leu Met
                 140                 145                 150

 Lys Val Lys Pro Lys His Leu Ser Cys Ile Gly Val Cys Ser Phe
                 155                 160                 165

 Leu Leu Ala Ala Arg Ile Val Glu Glu Asp Cys Asn Ile Pro Ser
                 170                 175                 180

 Thr His Asp Val Ile Arg Ile Ser Gln Cys Lys Cys Thr Ala Ser
                 185                 190                 195

 Asp Ile Lys Arg Met Glu Lys Ile Ile Ser Glu Lys Leu His Tyr
                 200                 205                 210

 Glu Leu Glu Ala Thr Thr Ala Leu Asn Phe Leu His Leu Tyr His
                 215                 220                 225

 Thr Ile Ile Leu Cys His Thr Ser Glu Arg Lys Glu Ile Leu Ser
                 230                 235                 240

 Leu Asp Lys Leu Glu Ala Gln Leu Lys Ala Cys Asn Cys Arg Leu
                 245                 250                 255

 Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu Cys Leu Leu
                 260                 265                 270

 Asn Leu Glu Val Glu Thr Leu Lys Ser Val Glu Leu Leu Glu Ile
                 275                 280                 285

 Leu Leu Leu Val Lys Lys His Ser Lys Ile Asn Asp Thr Glu Phe
                 290                 295                 300

 Phe Tyr Trp Arg Glu Leu Val Ser Lys Cys Leu Ala Glu Tyr Ser
                 305                 310                 315

 Ser Pro Glu Cys Cys Lys Pro Asp Leu Lys Lys Leu Val Trp Ile
                 320                 325                 330

 Val Ser Arg Arg Thr Ala Gln Asn Leu His Asn Ser Tyr Tyr Ser
                 335                 340                 345

 Val Pro Glu Leu Pro Thr Ile Pro Glu Gly Gly Cys Phe Asp Glu
                 350                 355                 360

 Ser Glu Ser Glu Asp Ser Cys Glu Asp Met Ser Cys Gly Glu Glu
                 365                 370                 375

 Ser Leu Ser Ser Ser Pro Pro Ser Asp Gln Glu Cys Thr Phe Phe
                 380                 385                 390

 Phe Asn Phe Lys Val Ala Gln Thr Leu Cys Phe Pro Ser
                 395                 400

<210> 711
<211> 2044
<212> DNA
<213> Homo sapien

<400> 711
 ccggtcggat gccggaccgg gggcaccgct gaggcggtgg gtccccgacc 50

 tgcgagacag gtttggaagc ccccgctgcg cccagtccgt gcggaccgcg 100

 aggccgcggg cgggtggagg cgcgtctccg gcacgatgaa ggatttgggg 150

 gcagagcact tggcaggtca tgaaggggtc caacttctcg ggttgttgaa 200

 cgtctacctg gaacaagaag agagattcca acctcgagaa aaagggctga 250

 gtttgattga ggctaccccg gagaatgata acactttgtg tccaggattg 300

 agaaatgcca aagttgaaga tttaaggagt ttagccaact tttttggatc 350

 ttgcactgaa acttttgtcc tggctgtcaa tattttggac aggttcttgg 400

 ctcttatgaa ggtgaaacct aaacatttgt cttgcattgg agtctgttct 450

 tttttgctgg ctgctagaat agttgaagaa gactgcaata ttccatccac 500

 tcatgatgtg atccggatta gtcagtgtaa atgtactgct tctgacataa 550

 aacggatgga aaaaataatt tcagaaaaat tgcactatga attggaagct 600

 actactgcct taaacttttt gcacttatac catactatta tactttgtca 650

 tacttcagaa aggaaagaaa tactgagcct tgataaacta gaagctcagc 700

 tgaaagcttg caactgccga ctcatctttt caaaagcaaa accatctgta 750

 ttagccttgt gccttctcaa tttggaagtg gaaactttga aatctgttga 800

 attactggaa attctcttgc tagttaaaaa acattccaag attaatgaca 850

 ctgagttctt ctactggaga gagttggttt ctaaatgcct agccgagtat 900

 tcttctcctg aatgttgcaa accagatctt aagaagttgg tttggatcgt 950

 ttcaaggcgc acagcccaga acctccacaa cagctactat agtgttcctg 1000

 agctgccaac gatacctgag gggggttgtt ttgatgaaag tgaaagtgag 1050

 gactcttgtg aagatatgag ttgtggagag gagagtctca gcagctctcc 1100

 tcccagtgat caagagtgca ccttcttttt caacttcaaa gtggcacaaa 1150

 cactgtgctt tccatcttag aaatctgatt gttctgtcag aatttatatt 1200

 tacagggttt caaagcaata aatgggggaa taggtagttt cctggtttag 1250

 cccccatcta gtcaggaatt aatatactgg aatacctacc ttctatttgt 1300

 tattcagatc agatctggcc tattttcata tttatcctaa gccatcaaat 1350

 ggggtagtgc ctcttaaacc attaacagta ctttagacat tggcacttta 1400

 tttttctcgt agatctttag ctactttggg gaggagggaa ggtgctgata 1450

 ccttcaattt gttacttttc aagattttta aaaataacta gtgtagctta 1500

 tcttaaacat tttataaaac cttcagatgt ctttaagcag attggaagta 1550

 tgcaagtgct tccttagcag ggacagtgga taatccttaa tggtttatca 1600

 tagatttcac cctcccccct tctcagaaga gtgagtatgc tcttaaatgt 1650

 caaacacatt tttgttgttt tgttttttaa atgatcagtg tctatttgat 1700

 gtgatgcaga tcttataaat ttgggaatta taatattgac atttctgtga 1750

 tttttatata tgtaatgtct taattgagat ttgtgttaag gcagaaataa 1800

 ttaggctagg gctcttagtt ttcattccta ttgccccaag tattgtcaaa 1850

 ctatggtatt attttaatgt tactttaaaa atccataatc tgctagtttt 1900

 gcatgtactt atatgaaaac agtgcagtaa gttgaaaact cagtatctat 1950

 ggaattgata aatgttgatc tggtgtagta tattttatcc gcattttctt 2000

 atattaaaaa atgttctgca tgattacatt ttatttgcct ttgt 2044

<210> 712
<211> 344
<212> PRT
<213> Homo sapien

<400> 712
 Met Lys Asp Leu Gly Ala Glu His Leu Ala Gly His Glu Gly Val
   1               5                  10                  15

 Gln Leu Leu Gly Leu Leu Asn Val Tyr Leu Glu Gln Glu Glu Arg
                  20                  25                  30

 Phe Gln Pro Arg Glu Lys Gly Leu Ser Leu Ile Glu Ala Thr Pro
                  35                  40                  45

 Glu Asn Asp Asn Thr Leu Cys Pro Gly Leu Arg Asn Ala Lys Val
                  50                  55                  60

 Glu Asp Leu Arg Ser Leu Ala Asn Phe Phe Gly Ser Cys Thr Glu
                  65                  70                  75

 Thr Phe Val Leu Ala Val Asn Ile Leu Asp Arg Phe Leu Ala Leu
                  80                  85                  90

 Met Lys Val Lys Pro Lys His Leu Ser Cys Ile Gly Val Cys Ser
                  95                 100                 105

 Phe Leu Leu Ala Ala Arg Ile Val Glu Glu Asp Cys Asn Ile Pro
                 110                 115                 120

 Ser Thr His Asp Val Ile Arg Ile Ser Gln Cys Lys Cys Thr Ala
                 125                 130                 135

 Ser Asp Ile Lys Arg Met Glu Lys Ile Ile Ser Glu Lys Leu His
                 140                 145                 150

 Tyr Glu Leu Glu Ala Thr Thr Ala Leu Asn Phe Leu His Leu Tyr
                 155                 160                 165

 His Thr Ile Ile Leu Cys His Thr Ser Glu Arg Lys Glu Ile Leu
                 170                 175                 180

 Ser Leu Asp Lys Leu Glu Ala Gln Leu Lys Ala Cys Asn Cys Arg
                 185                 190                 195

 Leu Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu Cys Leu
                 200                 205                 210

 Leu Asn Leu Glu Val Glu Thr Leu Lys Ser Val Glu Leu Leu Glu
                 215                 220                 225

 Ile Leu Leu Leu Val Lys Lys His Ser Lys Ile Asn Asp Thr Glu
                 230                 235                 240

 Phe Phe Tyr Trp Arg Glu Leu Val Ser Lys Cys Leu Ala Glu Tyr
                 245                 250                 255

 Ser Ser Pro Glu Cys Cys Lys Pro Asp Leu Lys Lys Leu Val Trp
                 260                 265                 270

 Ile Val Ser Arg Arg Thr Ala Gln Asn Leu His Asn Ser Tyr Tyr
                 275                 280                 285

 Ser Val Pro Glu Leu Pro Thr Ile Pro Glu Gly Gly Cys Phe Asp
                 290                 295                 300

 Glu Ser Glu Ser Glu Asp Ser Cys Glu Asp Met Ser Cys Gly Glu
                 305                 310                 315

 Glu Ser Leu Ser Ser Ser Pro Pro Ser Asp Gln Glu Cys Thr Phe
                 320                 325                 330

 Phe Phe Asn Phe Lys Val Ala Gln Thr Leu Cys Phe Pro Ser
                 335                 340

<210> 713
<211> 890
<212> DNA
<213> Homo sapien

<400> 713
 ggcggaccga agaacgcagg aagggggccg gggggacccg cccccggccg 50

 gccgcagcca tgaactccaa cgtggagaac ctacccccgc acatcatccg 100

 cctggtgtac aaggaggtga cgacactgac cgcagaccca cccgatggca 150

 tcaaggtctt tcccaacgag gaggacctca ccgacctcca ggtcaccatc 200

 gagggccctg aggggacccc atatgctgga ggtctgttcc gcatgaaact 250

 cctgctgggg aaggacttcc ctgcctcccc acccaagggc tacttcctga 300

 ccaagatctt ccacccgaac gtgggcgcca atggcgagat ctgcgtcaac 350

 gtgctcaaga gggactggac ggctgagctg ggcatccgac acgtactgct 400

 gaccatcaag tgcctgctga tccaccctaa ccccgagtct gcactcaacg 450

 aggaggcggg ccgcctgctc ttggagaact acgaggagta tgcggctcgg 500

 gcccgtctgc tcacagagat ccacgggggc gccggcgggc ccagcggcag 550

 ggccgaagcc ggtcgggccc tggccagtgg cactgaagct tcctccaccg 600

 accctggggc cccagggggc ccgggagggg ctgagggtcc catggccaag 650

 aagcatgctg gcgagcgcga taagaagctg gcggccaaga aaaagacgga 700

 caagaagcgg gcgctgcggg cgctgcggcg gctgtagtgg gctctcttcc 750

 tccttccacc gtgaccccaa cctctcctgt cccctccctc caactctgtc 800

 tctaagttat ttaaattatg gctggggtcg gggagggtac agggggcact 850

 gggacctgga tttgtttttc taaataaagt tggaaaagca 890

<210> 714
<211> 225
<212> PRT
<213> Homo sapien

<400> 714
 Met Asn Ser Asn Val Glu Asn Leu Pro Pro His Ile Ile Arg Leu
   1               5                  10                  15

 Val Tyr Lys Glu Val Thr Thr Leu Thr Ala Asp Pro Pro Asp Gly
                  20                  25                  30

 Ile Lys Val Phe Pro Asn Glu Glu Asp Leu Thr Asp Leu Gln Val
                  35                  40                  45

 Thr Ile Glu Gly Pro Glu Gly Thr Pro Tyr Ala Gly Gly Leu Phe
                  50                  55                  60

 Arg Met Lys Leu Leu Leu Gly Lys Asp Phe Pro Ala Ser Pro Pro
                  65                  70                  75

 Lys Gly Tyr Phe Leu Thr Lys Ile Phe His Pro Asn Val Gly Ala
                  80                  85                  90

 Asn Gly Glu Ile Cys Val Asn Val Leu Lys Arg Asp Trp Thr Ala
                  95                 100                 105

 Glu Leu Gly Ile Arg His Val Leu Leu Thr Ile Lys Cys Leu Leu
                 110                 115                 120

 Ile His Pro Asn Pro Glu Ser Ala Leu Asn Glu Glu Ala Gly Arg
                 125                 130                 135

 Leu Leu Leu Glu Asn Tyr Glu Glu Tyr Ala Ala Arg Ala Arg Leu
                 140                 145                 150

 Leu Thr Glu Ile His Gly Gly Ala Gly Gly Pro Ser Gly Arg Ala
                 155                 160                 165

 Glu Ala Gly Arg Ala Leu Ala Ser Gly Thr Glu Ala Ser Ser Thr
                 170                 175                 180

 Asp Pro Gly Ala Pro Gly Gly Pro Gly Gly Ala Glu Gly Pro Met
                 185                 190                 195

 Ala Lys Lys His Ala Gly Glu Arg Asp Lys Lys Leu Ala Ala Lys
                 200                 205                 210

 Lys Lys Thr Asp Lys Lys Arg Ala Leu Arg Ala Leu Arg Arg Leu
                 215                 220                 225

<210> 715
<211> 3293
<212> DNA
<213> Homo sapien

<400> 715
 cgctccctcc cctcctagct ggcttcggcg gggacggcgg cggcggcggc 50

 ggcggcggcg gcgggcgggg agggcgtgcg ccggccgaga ggtgtcggcg 100

 gcgaggcaaa ggaagtttca agtggaaggt cgtccgtcgg ccggcgcgtc 150

 ctcctgctct cctccgcagc atcatggcgg agccgagcgg ctcgcccgtg 200

 cacgtccagc ttccccagca ggcggccccg gtgacagcgg cggcggcggc 250

 ggccccggcg gccgcgacag cagcgccggc cccggcagct cccgcggccc 300

 cggccccggc cccggccccg gccccggcgg cacaggctgt cggctggccc 350

 atctgcaggg acgcgtacga gctgcaggag gttatcggca gtggagctac 400

 tgctgtggtt caggcagccc tatgcaaacc caggcaagaa cgtgtagcaa 450

 taaaacggat caacttggaa aaatgccaga ccagtatgga tgaactatta 500

 aaagaaattc aagccatgag tcagtgcagc catcccaacg tagtgaccta 550

 ttacacctct tttgtggtca aagatgaact ttggctggtc atgaaattac 600

 taagtggagg ttcaatgttg gatatcataa aatacattgt caaccgagga 650

 gaacacaaga atggagttct ggaagaggca ataatagcaa caattcttaa 700

 agaggttttg gaaggcttag actatctaca cagaaacggt cagattcaca 750

 gggatttgaa agctggtaat attcttctgg gtgaggatgg ttcagtacaa 800

 atagcagatt ttggggtaag tgcgttccta gcaacagggg gtgatgttac 850

 ccgaaataaa gtaagaaaaa cattcgttgg caccccatgt tggatggctc 900

 ctgaagtcat ggaacaggtg agaggctatg acttcaaggc tgacatgtgg 950

 agttttggaa taactgccat tgaattagca acaggagcag cgccttatca 1000

 caaatatcct cccatgaaag tgttaatgtt gactttgcaa aatgatccac 1050

 ccactttgga aacaggggta gaggataaag aaatgatgaa aaagtacggc 1100

 aagtccttta gaaaattact ttcactgtgt cttcagaaag atccttccaa 1150

 aaggcccaca gcagcagaac ttttaaaatg caaattcttc cagaaagcca 1200

 agaacagaga gtacctgatt gagaagctgc ttacaagaac accagacata 1250

 gcccaaagag ccaaaaaggt aagaagagtt cctgggtcaa gtggtcacct 1300

 tcataaaacc gaagacgggg actgggagtg gagtgacgac gagatggatg 1350

 agaagagcga agaagggaaa gcagcttttt ctcaggaaaa gtcacgaaga 1400

 gtaaaagaag aaaatccaga gattgcagtg agtgccagca ccatccccga 1450

 acaaatacag tccctctctg tgcacgactc tcagggccca cccaatgcta 1500

 atgaagacta cagagaagct tcttcttgtg ccgtgaacct cgttttgaga 1550

 ttaagaaact ccagaaagga acttaatgac atacgatttg agtttactcc 1600

 aggaagagat acagcagatg gtgtatctca ggagctcttc tctgctggct 1650

 tggtggatgg tcacgatgta gttatagtgg ctgctaattt acagaagatt 1700

 gtagatgatc ccaaagcttt aaaaacattg acatttaagt tggcttctgg 1750

 ctgtgatggg tcggagattc ctgatgaagt gaagctgatt gggtttgctc 1800

 agttgagtgt cagctgatgt atgtcccttg atgtcaccct gatctgtcat 1850

 gccccaccgc cacccctact cccttcaacc ctccctcttt ctgcccattt 1900

 cctcccaccc cctcactccc atttcctagc aaaatcagaa gattgtgaag 1950

 aggccggctt caacaaaatg ggataaaaaa ataatttttt aaaacttaca 2000

 acactccgag ttctgcttta ttctctagca atccacagta caagaacaag 2050

 caaatgccac agctgcacga ctgttgctca tttttccaaa agctatttaa 2100

 tattcttagc aatcaatttg gatatccctt aagtgaaaag aatctgaaat 2150

 acactcaggt ggtcttattt attggcaaca aaaggaattt tctatccaga 2200

 agcctatttc tcctttcatt gttgttattt ctgttataat actttaaatt 2250

 gtacatctga caatactgcc tcttttatgt tgtatttaga aattaatata 2300

 cttataaaat taagatttat tagccaaact tgaattctag ttttaaaact 2350

 gactgtgaat tttatttttc atatatttat gcattacaca ccttagctat 2400

 aagaaaaaaa gggttttgat tatatgcttc ttgcagttaa tctcgttatt 2450

 taaacaaaaa gttttgggtc tgtctttgga gtatttgtaa cttctaaatt 2500

 ttgaaatgac tgaattagga atttggatgc ttattctttt agtctgtttg 2550

 cctaaaaacc aatttacaat ctgactgtct cttgggagag ggaggtgcct 2600

 tgcaaacttt cacattaaga atgtgcctga ggctgcttta ctctggaata 2650

 gtctcagatc taaaatttcc tctatataag gtggcatatg ttaagttttg 2700

 cttcattgga ccgtttagaa tgctatgtaa aatgttgcca ttctgttaga 2750

 ttgctaacta tatacccatc tctgatttgg ctctccttaa gtgataggat 2800

 ttgttattct aaaggtgata aacttgaaaa tatcagaatc tgagttttac 2850

 ttgaaatttt gcagaatacc caggtggagt gaaaattgga agggttttgt 2900

 gcaatgacta aaaggtaaaa cgctgttaag gttcaagaat caatactttc 2950

 aacccaagta gccccctgct tgactgtata ttatggaact agtaaacctt 3000

 aggattttga aaattggagt ctaatctttc aaggaggtgg gctcccagga 3050

 tggtaccatt gctctttcct agctaaccct agatatggca gctctttaat 3100

 gtacttcaaa aagcaaatat atattactaa ggaaaaaaag ttatttataa 3150

 ttgccttgtc ataattgtta aggtgttcta gagccatttg catacaattt 3200

 aatgtaattt cattccattc tattgtttac acaacgatta ctcgaagatg 3250

 actgcaaagg taaaaggaaa ataaaagtgt attgcacaat gag 3293

<210> 716
<211> 547
<212> PRT
<213> Homo sapien

<400> 716
 Met Ala Glu Pro Ser Gly Ser Pro Val His Val Gln Leu Pro Gln
   1               5                  10                  15

 Gln Ala Ala Pro Val Thr Ala Ala Ala Ala Ala Ala Pro Ala Ala
                  20                  25                  30

 Ala Thr Ala Ala Pro Ala Pro Ala Ala Pro Ala Ala Pro Ala Pro
                  35                  40                  45

 Ala Pro Ala Pro Ala Pro Ala Ala Gln Ala Val Gly Trp Pro Ile
                  50                  55                  60

 Cys Arg Asp Ala Tyr Glu Leu Gln Glu Val Ile Gly Ser Gly Ala
                  65                  70                  75

 Thr Ala Val Val Gln Ala Ala Leu Cys Lys Pro Arg Gln Glu Arg
                  80                  85                  90

 Val Ala Ile Lys Arg Ile Asn Leu Glu Lys Cys Gln Thr Ser Met
                  95                 100                 105

 Asp Glu Leu Leu Lys Glu Ile Gln Ala Met Ser Gln Cys Ser His
                 110                 115                 120

 Pro Asn Val Val Thr Tyr Tyr Thr Ser Phe Val Val Lys Asp Glu
                 125                 130                 135

 Leu Trp Leu Val Met Lys Leu Leu Ser Gly Gly Ser Met Leu Asp
                 140                 145                 150

 Ile Ile Lys Tyr Ile Val Asn Arg Gly Glu His Lys Asn Gly Val
                 155                 160                 165

 Leu Glu Glu Ala Ile Ile Ala Thr Ile Leu Lys Glu Val Leu Glu
                 170                 175                 180

 Gly Leu Asp Tyr Leu His Arg Asn Gly Gln Ile His Arg Asp Leu
                 185                 190                 195

 Lys Ala Gly Asn Ile Leu Leu Gly Glu Asp Gly Ser Val Gln Ile
                 200                 205                 210

 Ala Asp Phe Gly Val Ser Ala Phe Leu Ala Thr Gly Gly Asp Val
                 215                 220                 225

 Thr Arg Asn Lys Val Arg Lys Thr Phe Val Gly Thr Pro Cys Trp
                 230                 235                 240

 Met Ala Pro Glu Val Met Glu Gln Val Arg Gly Tyr Asp Phe Lys
                 245                 250                 255

 Ala Asp Met Trp Ser Phe Gly Ile Thr Ala Ile Glu Leu Ala Thr
                 260                 265                 270

 Gly Ala Ala Pro Tyr His Lys Tyr Pro Pro Met Lys Val Leu Met
                 275                 280                 285

 Leu Thr Leu Gln Asn Asp Pro Pro Thr Leu Glu Thr Gly Val Glu
                 290                 295                 300

 Asp Lys Glu Met Met Lys Lys Tyr Gly Lys Ser Phe Arg Lys Leu
                 305                 310                 315

 Leu Ser Leu Cys Leu Gln Lys Asp Pro Ser Lys Arg Pro Thr Ala
                 320                 325                 330

 Ala Glu Leu Leu Lys Cys Lys Phe Phe Gln Lys Ala Lys Asn Arg
                 335                 340                 345

 Glu Tyr Leu Ile Glu Lys Leu Leu Thr Arg Thr Pro Asp Ile Ala
                 350                 355                 360

 Gln Arg Ala Lys Lys Val Arg Arg Val Pro Gly Ser Ser Gly His
                 365                 370                 375

 Leu His Lys Thr Glu Asp Gly Asp Trp Glu Trp Ser Asp Asp Glu
                 380                 385                 390

 Met Asp Glu Lys Ser Glu Glu Gly Lys Ala Ala Phe Ser Gln Glu
                 395                 400                 405

 Lys Ser Arg Arg Val Lys Glu Glu Asn Pro Glu Ile Ala Val Ser
                 410                 415                 420

 Ala Ser Thr Ile Pro Glu Gln Ile Gln Ser Leu Ser Val His Asp
                 425                 430                 435

 Ser Gln Gly Pro Pro Asn Ala Asn Glu Asp Tyr Arg Glu Ala Ser
                 440                 445                 450

 Ser Cys Ala Val Asn Leu Val Leu Arg Leu Arg Asn Ser Arg Lys
                 455                 460                 465

 Glu Leu Asn Asp Ile Arg Phe Glu Phe Thr Pro Gly Arg Asp Thr
                 470                 475                 480

 Ala Asp Gly Val Ser Gln Glu Leu Phe Ser Ala Gly Leu Val Asp
                 485                 490                 495

 Gly His Asp Val Val Ile Val Ala Ala Asn Leu Gln Lys Ile Val
                 500                 505                 510

 Asp Asp Pro Lys Ala Leu Lys Thr Leu Thr Phe Lys Leu Ala Ser
                 515                 520                 525

 Gly Cys Asp Gly Ser Glu Ile Pro Asp Glu Val Lys Leu Ile Gly
                 530                 535                 540

 Phe Ala Gln Leu Ser Val Ser
                 545

<210> 717
<211> 848
<212> DNA
<213> Homo sapien

<400> 717
 ctggccagcg aacaaagtta catgtcctgt agcttaaaac cacagctggc 50

 agggtgagaa gctagatgcc cctgcagttt tggccctggg agccagggca 100

 gaggaatgta gggcctgcat ggagaagggt tctgccctgc ctgaggagga 150

 ggacacagca caagggcaca ttgcccatgg ctgggaacat gacccagcct 200

 gaaagataca ggggatcatg ttaaaaatag cagtattatt tttcgtctca 250

 atggtattgt aactaagtta tttactcctc ctgctcctca cccctgtagg 300

 gaaaccttgg agaggagagt ggcaggtggg ctgcctgctg tgttaagagg 350

 acttagtttg tgatgtaagg cactgtcagg aatggggggc gggccagggt 400

 gggaagagaa gaaatagcag agcctatttt ggtgaggttt tttgttttta 450

 agtcaaagaa gactcagtat gctttccctg aggaatgaaa aagggattga 500

 ggagttgcct gactcctggg tgggtggggt acaggcagtt aggtgctgaa 550

 tgaagctgcc atccttgctg cagcttctaa ctggtaaaaa gatccaggga 600

 tggagatggg aaggttagaa aggcagccct cacctctgag gacagaggcc 650

 ggggtccagg cccgtgggcg caaaggtgcc tcatagcata gccagcattc 700

 agcacacaca aacctactgc ccacatttgg gctcagggtt ggccatttgc 750

 tagttctgct gccctcttaa gatctgactg ccaaataaat catcctcatg 800

 tccctaaaaa aaatctatgt cgggtgcgga gaaagaggta atgaaatg 848

<210> 718
<211> 16
<212> PRT
<213> Homo sapien

<400> 718
 Met Ser Leu Lys Lys Ile Tyr Val Gly Cys Gly Glu Arg Gly Asn
   1               5                  10                  15

 Glu


<210> 719
<211> 2107
<212> DNA
<213> Homo sapien

<400> 719
 ggaagggtcc cgggaacgtg gtggggcagg gcctccgagc gtggttggac 50

 tttgaagggg atcggcgcca tgctgcatcc cctttttgga attgctcaac 100

 caggtggtaa ccggcgccgc ttcctggcct tgggaggtgg ttcctttctt 150

 aacccacaag aacctctccc aagagaactt ggtcctgatg tctgaccatg 200

 gagatgtgag cctcccgccc gaagaccggg tgagggctct ctcccagctg 250

 ggtagtgcgg tagaggtgaa tgaagacatt ccaccccgtc ggtacttccg 300

 ctctggagtt gagattatcc gaatggcatc catttactct gaggaaggca 350

 acattgaaca tgccttcatc ctctataaca agtatatcac gctctttatt 400

 gagaaactac caaaacatcg agattacaaa tctgctgtca ttcctgaaaa 450

 gaaagacaca gtaaagaaat taaaggagat tgcatttccc aaagcagaag 500

 agctgaaggc agagctgtta aaacgatata ccaaagaata tacagaatat 550

 aatgaagaaa agaagaagga agcagaggaa ttggcccgga acatggccat 600

 ccagcaagag ctggaaaagg aaaaacagag ggtagcacaa cagaagcagc 650

 agcaattgga acaggaacag ttccatgcct tcgaggagat gatccggaac 700

 caggagctag aaaaagagcg actgaaaatt gtacaggagt ttgggaaggt 750

 agaccctggc ctaggtggcc cgctagtgcc tgacttggag aagccctcct 800

 tagatgtgtt ccccacctta acagtctcat ccatacagcc ttcagactgt 850

 cacacaactg taaggccagc taagccacct gtggtggaca ggtccttgaa 900

 acctggagca ctgagcaact cagaaagtat tcccacaatc gatggattgc 950

 gccatgtggt ggtgcctggg cggctgtgcc cacagtttct ccagttagcc 1000

 agtgccaaca ctgcccgggg agtggagaca tgtggaattc tctgtggaaa 1050

 actgatgagg aatgaattta ccattaccca tgttctcatc cccaagcaaa 1100

 gtgctgggtc tgattactgc aacacagaga acgaagaaga acttttcctc 1150

 atacaggatc agcagggcct catcacactg ggctggattc atactcaccc 1200

 cacacagacc gcgtttctct ccagtgtcga cctacacact cactgctctt 1250

 accagatgat gttgccagag tcagtagcca ttgtttgctc ccccaagttc 1300

 caggaaactg gattctttaa actaactgac catggactag aggagatttc 1350

 ttcctgtcgc cagaaaggat ttcatccaca cagcaaggat ccacctctgt 1400

 tctgtagctg cagccacgtg actgttgtgg acagagcagt gaccatcaca 1450

 gaccttcgat gagcgtttga gtccaacacc ttccaagaac aacaaaacca 1500

 tatcagtgta ctgtagcccc ttaatttaag ctttctagaa agctttggaa 1550

 gtttttgtag atagtagaaa ggggggcatc acctgagaaa gagctgattt 1600

 tgtatttcag gtttgaaaag aaataactga acatattttt taggcaagtc 1650

 agaaagagaa catggtcacc caaaagcaac tgtaactcag aaattaagtt 1700

 actcagaaat taagtagctc agaaattaag aaagaatggt ataatgaacc 1750

 cccatatacc cttccttctg gattcaccaa ttgttaacat ttttttcctc 1800

 tcagctatcc ttctaatttc tctctaattt caatttgttt atatttacct 1850

 ctgggctcaa taagggcatc tgtgcagaaa tttggaagcc atttagaaaa 1900

 tcttttggat tttcctgtgg tttatggcaa tatgaatgga gcttattact 1950

 ggggtgaggg acagcttact ccatttgacc agattgtttg gctaacacat 2000

 cccgaagaat gattttgtca ggaattattg ttatttaata aatatttcag 2050

 gatatttttc ctctacaata aagtaacaat taacttaaaa aaaaaaaaaa 2100

 aaaaaaa 2107

<210> 720
<211> 424
<212> PRT
<213> Homo sapien

<400> 720
 Met Ser Asp His Gly Asp Val Ser Leu Pro Pro Glu Asp Arg Val
   1               5                  10                  15

 Arg Ala Leu Ser Gln Leu Gly Ser Ala Val Glu Val Asn Glu Asp
                  20                  25                  30

 Ile Pro Pro Arg Arg Tyr Phe Arg Ser Gly Val Glu Ile Ile Arg
                  35                  40                  45

 Met Ala Ser Ile Tyr Ser Glu Glu Gly Asn Ile Glu His Ala Phe
                  50                  55                  60

 Ile Leu Tyr Asn Lys Tyr Ile Thr Leu Phe Ile Glu Lys Leu Pro
                  65                  70                  75

 Lys His Arg Asp Tyr Lys Ser Ala Val Ile Pro Glu Lys Lys Asp
                  80                  85                  90

 Thr Val Lys Lys Leu Lys Glu Ile Ala Phe Pro Lys Ala Glu Glu
                  95                 100                 105

 Leu Lys Ala Glu Leu Leu Lys Arg Tyr Thr Lys Glu Tyr Thr Glu
                 110                 115                 120

 Tyr Asn Glu Glu Lys Lys Lys Glu Ala Glu Glu Leu Ala Arg Asn
                 125                 130                 135

 Met Ala Ile Gln Gln Glu Leu Glu Lys Glu Lys Gln Arg Val Ala
                 140                 145                 150

 Gln Gln Lys Gln Gln Gln Leu Glu Gln Glu Gln Phe His Ala Phe
                 155                 160                 165

 Glu Glu Met Ile Arg Asn Gln Glu Leu Glu Lys Glu Arg Leu Lys
                 170                 175                 180

 Ile Val Gln Glu Phe Gly Lys Val Asp Pro Gly Leu Gly Gly Pro
                 185                 190                 195

 Leu Val Pro Asp Leu Glu Lys Pro Ser Leu Asp Val Phe Pro Thr
                 200                 205                 210

 Leu Thr Val Ser Ser Ile Gln Pro Ser Asp Cys His Thr Thr Val
                 215                 220                 225

 Arg Pro Ala Lys Pro Pro Val Val Asp Arg Ser Leu Lys Pro Gly
                 230                 235                 240

 Ala Leu Ser Asn Ser Glu Ser Ile Pro Thr Ile Asp Gly Leu Arg
                 245                 250                 255

 His Val Val Val Pro Gly Arg Leu Cys Pro Gln Phe Leu Gln Leu
                 260                 265                 270

 Ala Ser Ala Asn Thr Ala Arg Gly Val Glu Thr Cys Gly Ile Leu
                 275                 280                 285

 Cys Gly Lys Leu Met Arg Asn Glu Phe Thr Ile Thr His Val Leu
                 290                 295                 300

 Ile Pro Lys Gln Ser Ala Gly Ser Asp Tyr Cys Asn Thr Glu Asn
                 305                 310                 315

 Glu Glu Glu Leu Phe Leu Ile Gln Asp Gln Gln Gly Leu Ile Thr
                 320                 325                 330

 Leu Gly Trp Ile His Thr His Pro Thr Gln Thr Ala Phe Leu Ser
                 335                 340                 345

 Ser Val Asp Leu His Thr His Cys Ser Tyr Gln Met Met Leu Pro
                 350                 355                 360

 Glu Ser Val Ala Ile Val Cys Ser Pro Lys Phe Gln Glu Thr Gly
                 365                 370                 375

 Phe Phe Lys Leu Thr Asp His Gly Leu Glu Glu Ile Ser Ser Cys
                 380                 385                 390

 Arg Gln Lys Gly Phe His Pro His Ser Lys Asp Pro Pro Leu Phe
                 395                 400                 405

 Cys Ser Cys Ser His Val Thr Val Val Asp Arg Ala Val Thr Ile
                 410                 415                 420

 Thr Asp Leu Arg


<210> 721
<211> 668
<212> DNA
<213> Homo sapien

<400> 721
 cggggacccg gctgcggtgg ctgcgggact gacgagaaac tactaaagtt 50

 cctggggaag caaagtagaa tttcataaga acaaaatgga tggagaggag 100

 aaaacctatg gtggctgtga aggacctgat gccatgtatg tcaaattgat 150

 atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat 200

 caggcacgat aaaagccatg ttgagtggcc caggtcagtt tgctgagaac 250

 gaaaccaatg aggtcaattt tagagagata ccttcacatg tgctatcgaa 300

 agtatgcatg tattttacgt acaaggttcg ctacactaac agctccaccg 350

 agattcctga attcccaatt gcacctgaaa ttgcactgga actgctgatg 400

 gctgcgaact tcttagattg ttaaataaaa taaattataa taaactgtta 450

 actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat 500

 atagcatgtt gcctgtatgc agttgaacta tataaagttc attgcaaagc 550

 agattatctt gtttttttgc atagcaatca aagttgaaat ttgtttgcta 600

 catcaacaaa ttaaggacat tttcacaaac tgagaaataa acaaatatgc 650

 caattaaaaa aaaaaaaa 668

<210> 722
<211> 112
<212> PRT
<213> Homo sapien

<400> 722
 Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp
   1               5                  10                  15

 Ala Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile
                  20                  25                  30

 Val Lys Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met
                  35                  40                  45

 Leu Ser Gly Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val
                  50                  55                  60

 Asn Phe Arg Glu Ile Pro Ser His Val Leu Ser Lys Val Cys Met
                  65                  70                  75

 Tyr Phe Thr Tyr Lys Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile
                  80                  85                  90

 Pro Glu Phe Pro Ile Ala Pro Glu Ile Ala Leu Glu Leu Leu Met
                  95                 100                 105

 Ala Ala Asn Phe Leu Asp Cys
                 110

<210> 723
<211> 2618
<212> DNA
<213> Homo sapien

<400> 723
 tgcagctagt gtgtcaactc agcgtttctc ctctcgtccc tggaagagct 50

 aaagatggct gaatttctag atgaccagga aactcgactg tgtgacaact 100

 gcaaaaaaga aattcctgtg tttaacttta ccatccatga gatccactgt 150

 caaaggaaca ttggtatgtg tcctacctgt aaggaaccat ttcccaaatc 200

 tgacatggag actcacatgg ctgcagaaca ctgtcaggtg acctgcaaat 250

 gtaacaagaa gttggagaag aggctgttaa agaagcatga ggagactgag 300

 tgccctttgc ggcttgctgt ctgccagcac tgtgatttag aactttccat 350

 tctcaaactg aaggaacatg aagattattg tggtgcccgg acggaactat 400

 gtggcaactg tggtcgcaat gtccttgtga aagatctgaa gactcaccct 450

 gaagtttgtg ggagagaggg ggaggaaaag agaaatgagg ttgccatacc 500

 tcctaatgca tatgatgaat cttggggtca ggatggaatc tggattgcat 550

 cccaactcct cagacaaatt gaggctctgg acccacccat gaggctgccg 600

 cgaaggcccc tgagagcctt tgaatcagat gttttccaca atagaactac 650

 caaccaaagg aacattacag cccaggtttc aattcagaat aatctgtttg 700

 aagaacaaga gaggcaggaa aggaatagag gccaacagcc ccccaaagag 750

 ggtggtgaag agagtgcaaa cttggacttc atgttggccc taagtctgca 800

 aaatgaaggc caagcctcca gtgtggcaga gcaggacttc tggagggccg 850

 tatgtgaggc cgaccagtct catggcggtc ccaggtctct cagtgacata 900

 aagggtgcag ctgacgagat catgttgcct tgtgaatttt gtgaggagct 950

 ctacccagag gaactgctga ttgaccatca gacaagctgt aacccttcac 1000

 gtgccttacc ttcactcaat actggcagct cttcccccag aggggtggag 1050

 gaacctgatg tcatcttcca gaacttcttg caacaggctg caagtaacca 1100

 gttagactct ttgatgggcc tgagcaattc acaccctgtg gaggagagca 1150

 tcattatccc atgtgaattc tgtggggtac agctggaaga ggaggtgctg 1200

 ttccatcacc aggaccagtg tgaccaacgc ccagccactg caaccaacca 1250

 tgtgacagag gggattccta gactggattc ccagcctcaa gagacctcac 1300

 cagagctgcc caggaggcgt gtcagacacc agggagacct gtcttctggt 1350

 tacctggatg atactaagca ggaaacagct aatgggccca cctcctgtct 1400

 gcctcccagc cgacccatta acaatatgac agctacctat aaccagctat 1450

 cgagatcaac atcaggcccc agacctgggt gccagcccag ctctccttgt 1500

 gtgccgaagc tcagcaactc agacagccag gacatccagg ggcggaatcg 1550

 agacagccag aatggggcca tagcccctgg gcacgtttca gtgattcgcc 1600

 ctcctcaaaa tctctaccca gaaaacattg tgccctcttt ctcccctggg 1650

 ccttcaggga gatacggagc tagtggtagg agtgaaggtg gcaggaattc 1700

 ccgggtcacc cctgcagctg ccaactaccg cagcagaact gcaaaggcaa 1750

 agccttccaa gcaacaggga gctggggatg cagaagagga agaggaggag 1800

 taatggtgtc tccagagact ttacatcggt tcctgtcttc tgtgcacagc 1850

 agcacttgcc gctgtgcagg cccacctctt tggctctttg ggtgggagag 1900

 tttttccaga ttttagattt ttctaggtta tggccatttt gtgtcttttg 1950

 aggttgtgct gtgggggttt gggtttgagg gaagggagca gggtggcggt 2000

 tgaggaacgc ttcagcctta gctgctacct ttcggcagca gtgaaataca 2050

 agctgcagcc tcggctgcca gggctccctt ttgacttatt gtcgccactg 2100

 ccccttggtg ctgtgtggtc ccagtggaag gaggggaaga ttttggaaac 2150

 ctggtagcca ccagtaaggt gattctctgc cctgttgggg cctaaatttg 2200

 ggggcttttg ggcaacctct ccgtgtactg cgtctgtcca cactcgattg 2250

 ggccccaggt gtgtatgagg cgctctggta aggtgctcag gccagttgca 2300

 atgtctgtca gtaacgaggc ttttgatgtg ttgagctgga ggtgagtgga 2350

 ccgggggctg tgttttaagc tgcttccttg gcatttgcat cactgccttc 2400

 tgttcccggg ggagcatgga tcttttgtcc tcactgcttt ctaatgggga 2450

 gggctgaggg ctccctgtcc ccacagcagg tatgtttgct ctgccccagc 2500

 cccacacttg ctctgaaaac caagtgtcag agccccttcc ccttgttttt 2550

 attttactgt tataataatt attaacttcc ttgtaataga aataaagttt 2600

 gtacttggag ttcagctc 2618

<210> 724
<211> 582
<212> PRT
<213> Homo sapien

<400> 724
 Met Ala Glu Phe Leu Asp Asp Gln Glu Thr Arg Leu Cys Asp Asn
   1               5                  10                  15

 Cys Lys Lys Glu Ile Pro Val Phe Asn Phe Thr Ile His Glu Ile
                  20                  25                  30

 His Cys Gln Arg Asn Ile Gly Met Cys Pro Thr Cys Lys Glu Pro
                  35                  40                  45

 Phe Pro Lys Ser Asp Met Glu Thr His Met Ala Ala Glu His Cys
                  50                  55                  60

 Gln Val Thr Cys Lys Cys Asn Lys Lys Leu Glu Lys Arg Leu Leu
                  65                  70                  75

 Lys Lys His Glu Glu Thr Glu Cys Pro Leu Arg Leu Ala Val Cys
                  80                  85                  90

 Gln His Cys Asp Leu Glu Leu Ser Ile Leu Lys Leu Lys Glu His
                  95                 100                 105

 Glu Asp Tyr Cys Gly Ala Arg Thr Glu Leu Cys Gly Asn Cys Gly
                 110                 115                 120

 Arg Asn Val Leu Val Lys Asp Leu Lys Thr His Pro Glu Val Cys
                 125                 130                 135

 Gly Arg Glu Gly Glu Glu Lys Arg Asn Glu Val Ala Ile Pro Pro
                 140                 145                 150

 Asn Ala Tyr Asp Glu Ser Trp Gly Gln Asp Gly Ile Trp Ile Ala
                 155                 160                 165

 Ser Gln Leu Leu Arg Gln Ile Glu Ala Leu Asp Pro Pro Met Arg
                 170                 175                 180

 Leu Pro Arg Arg Pro Leu Arg Ala Phe Glu Ser Asp Val Phe His
                 185                 190                 195

 Asn Arg Thr Thr Asn Gln Arg Asn Ile Thr Ala Gln Val Ser Ile
                 200                 205                 210

 Gln Asn Asn Leu Phe Glu Glu Gln Glu Arg Gln Glu Arg Asn Arg
                 215                 220                 225

 Gly Gln Gln Pro Pro Lys Glu Gly Gly Glu Glu Ser Ala Asn Leu
                 230                 235                 240

 Asp Phe Met Leu Ala Leu Ser Leu Gln Asn Glu Gly Gln Ala Ser
                 245                 250                 255

 Ser Val Ala Glu Gln Asp Phe Trp Arg Ala Val Cys Glu Ala Asp
                 260                 265                 270

 Gln Ser His Gly Gly Pro Arg Ser Leu Ser Asp Ile Lys Gly Ala
                 275                 280                 285

 Ala Asp Glu Ile Met Leu Pro Cys Glu Phe Cys Glu Glu Leu Tyr
                 290                 295                 300

 Pro Glu Glu Leu Leu Ile Asp His Gln Thr Ser Cys Asn Pro Ser
                 305                 310                 315

 Arg Ala Leu Pro Ser Leu Asn Thr Gly Ser Ser Ser Pro Arg Gly
                 320                 325                 330

 Val Glu Glu Pro Asp Val Ile Phe Gln Asn Phe Leu Gln Gln Ala
                 335                 340                 345

 Ala Ser Asn Gln Leu Asp Ser Leu Met Gly Leu Ser Asn Ser His
                 350                 355                 360

 Pro Val Glu Glu Ser Ile Ile Ile Pro Cys Glu Phe Cys Gly Val
                 365                 370                 375

 Gln Leu Glu Glu Glu Val Leu Phe His His Gln Asp Gln Cys Asp
                 380                 385                 390

 Gln Arg Pro Ala Thr Ala Thr Asn His Val Thr Glu Gly Ile Pro
                 395                 400                 405

 Arg Leu Asp Ser Gln Pro Gln Glu Thr Ser Pro Glu Leu Pro Arg
                 410                 415                 420

 Arg Arg Val Arg His Gln Gly Asp Leu Ser Ser Gly Tyr Leu Asp
                 425                 430                 435

 Asp Thr Lys Gln Glu Thr Ala Asn Gly Pro Thr Ser Cys Leu Pro
                 440                 445                 450

 Pro Ser Arg Pro Ile Asn Asn Met Thr Ala Thr Tyr Asn Gln Leu
                 455                 460                 465

 Ser Arg Ser Thr Ser Gly Pro Arg Pro Gly Cys Gln Pro Ser Ser
                 470                 475                 480

 Pro Cys Val Pro Lys Leu Ser Asn Ser Asp Ser Gln Asp Ile Gln
                 485                 490                 495

 Gly Arg Asn Arg Asp Ser Gln Asn Gly Ala Ile Ala Pro Gly His
                 500                 505                 510

 Val Ser Val Ile Arg Pro Pro Gln Asn Leu Tyr Pro Glu Asn Ile
                 515                 520                 525

 Val Pro Ser Phe Ser Pro Gly Pro Ser Gly Arg Tyr Gly Ala Ser
                 530                 535                 540

 Gly Arg Ser Glu Gly Gly Arg Asn Ser Arg Val Thr Pro Ala Ala
                 545                 550                 555

 Ala Asn Tyr Arg Ser Arg Thr Ala Lys Ala Lys Pro Ser Lys Gln
                 560                 565                 570

 Gln Gly Ala Gly Asp Ala Glu Glu Glu Glu Glu Glu
                 575                 580

<210> 725
<211> 2371
<212> DNA
<213> Homo sapien

<400> 725
 agctggctga gaggggactg ggcgccggcg gggaaggagg agcgctaggt 50

 cggtgtacga ccgagattag ggtgcgtgcc agctccggga ggccgcggtg 100

 aggggccggg cccaagctgc cgacccgagc cgatcgtcag ggtcgccagc 150

 gcctcagctc tgtggaggag cagcagtagt cggagggtgc aggatattag 200

 aaatggctac tccccagtca attttcatct ttgcaatctg cattttaatg 250

 ataacagaat taattctggc ctcaaaaagc tactatgata tcttaggtgt 300

 gccaaaatcg gcatcagagc gccaaatcaa gaaggccttt cacaagttgg 350

 ccatgaagta ccaccctgac aaaaataaga gcccggatgc tgaagcaaaa 400

 ttcagagaga ttgcagaagc atatgaaaca ctctcagatg ctaatagacg 450

 aaaagagtat gatacacttg gacacagtgc ttttactagt ggtaaaggac 500

 aaagaggtag tggaagttct tttgagcagt catttaactt caattttgat 550

 gacttattta aagactttgg cttttttggt caaaaccaaa acactggatc 600

 caagaagcgt tttgaaaatc atttccagac acgccaggat ggtggttcca 650

 gtagacaaag gcatcatttc caagaatttt cttttggagg tggattattt 700

 gatgacatgt ttgaagatat ggagaaaatg ttttctttta gtggttttga 750

 ctctaccaat cagcatacag tacagactga aaatagattt catggatcta 800

 gcaagcactg caggactgtc actcaacgaa gaggaaatat ggttactaca 850

 tacactgact gttcaggaca gtagttctta ttctattctc actaaatcca 900

 actggttgac tcttcctcat tatctttgat gctaaacaat tttctgtgaa 950

 ctattttgac aagtgcatga tttcacttta aacaatttga tatagctatt 1000

 aaatatattt aagggttttt tttttttgac aaattcaaca ttcaacgagt 1050

 agacaaaatg ctaattattt ccctgattag gaaagtttct ttaaaaaaca 1100

 cgtaattttg cctagtgctt tttctctacc tgcccttggg ctcactaata 1150

 tcaccagtat tattaccaag aaaatattga gtttacctga ttaaacttta 1200

 aaagttaatt gtagatttaa attgtgtgaa cctaatgatt tttgcagtga 1250

 aacctttact aattcaaagt tgcatgttct atgacatctg tgacttgcgt 1300

 tgcagagtgt acatgaaact gtataattga gtcattcagt aaaggagaac 1350

 agtatcttgg ttaattgcta ctgaaaggtt gagaaaggaa tggtttgata 1400

 tttaccacag cgctgtgcct ttctacagta gaactggggt aaaggaaatg 1450

 gttttattgc ccatagtcat ttaggctgga aaaaagttga aaacttaacg 1500

 aaatattgcc aagagattgt tatgtgtttg gttccagcct aaaaatgatt 1550

 ttgtagtgtt gaaatcatag ctacttacat agctttttca tatttctttc 1600

 ttagttgttg gcactcttag gtcttagtat ggatttatgt gtttgtgtgt 1650

 gtgtagttta tcctctctct catctttatc tagagattga ctgatacctc 1700

 attctgtttg taaaaccagc cagtaatttc tgtgcaacct tactatgtgc 1750

 aatattttta aatcctgaga aatgtgtgct tttgttttcg gatagactta 1800

 tttctttagt tctgcacttt tccacattat actccatatg agtattaatc 1850

 ctatggatac atattaaaac aagtgtctca tacaacattg tatgtgagag 1900

 aaatataaat atttacaacc tgatattcgt tgttgtttta ttgttaaaag 1950

 tttattatgc aactctggag gtatagaggg catataagct atgggacata 2000

 tgctgatcac aggctatatt catgaagtta cttttgacca acctgaaaac 2050

 tgataggatt ttgtttgtca tttggtaatt tctactgcat tcttaccatc 2100

 cttctctcac aaattttgat agcttgaaga tctttttaat tataattttg 2150

 ttgtatttgt ttcctaggag caagtgttcc tgctgccagt tctttcctct 2200

 ttaggcgtgg ttgagaaaaa gcagaaactt tacataaagc tgtatttctt 2250

 aatcatcttt aatttgaaac ttaagaaaat gaatttattc tgttatattt 2300

 atgtaactta tttcctggaa gttatatcta ctagttttgt ttgataataa 2350

 taaaattagc tataccttga a 2371

<210> 726
<211> 223
<212> PRT
<213> Homo sapien

<400> 726
 Met Ala Thr Pro Gln Ser Ile Phe Ile Phe Ala Ile Cys Ile Leu
   1               5                  10                  15

 Met Ile Thr Glu Leu Ile Leu Ala Ser Lys Ser Tyr Tyr Asp Ile
                  20                  25                  30

 Leu Gly Val Pro Lys Ser Ala Ser Glu Arg Gln Ile Lys Lys Ala
                  35                  40                  45

 Phe His Lys Leu Ala Met Lys Tyr His Pro Asp Lys Asn Lys Ser
                  50                  55                  60

 Pro Asp Ala Glu Ala Lys Phe Arg Glu Ile Ala Glu Ala Tyr Glu
                  65                  70                  75

 Thr Leu Ser Asp Ala Asn Arg Arg Lys Glu Tyr Asp Thr Leu Gly
                  80                  85                  90

 His Ser Ala Phe Thr Ser Gly Lys Gly Gln Arg Gly Ser Gly Ser
                  95                 100                 105

 Ser Phe Glu Gln Ser Phe Asn Phe Asn Phe Asp Asp Leu Phe Lys
                 110                 115                 120

 Asp Phe Gly Phe Phe Gly Gln Asn Gln Asn Thr Gly Ser Lys Lys
                 125                 130                 135

 Arg Phe Glu Asn His Phe Gln Thr Arg Gln Asp Gly Gly Ser Ser
                 140                 145                 150

 Arg Gln Arg His His Phe Gln Glu Phe Ser Phe Gly Gly Gly Leu
                 155                 160                 165

 Phe Asp Asp Met Phe Glu Asp Met Glu Lys Met Phe Ser Phe Ser
                 170                 175                 180

 Gly Phe Asp Ser Thr Asn Gln His Thr Val Gln Thr Glu Asn Arg
                 185                 190                 195

 Phe His Gly Ser Ser Lys His Cys Arg Thr Val Thr Gln Arg Arg
                 200                 205                 210

 Gly Asn Met Val Thr Thr Tyr Thr Asp Cys Ser Gly Gln
                 215                 220

<210> 727
<211> 2371
<212> DNA
<213> Homo sapien

<400> 727
 agctggctga gaggggactg ggcgccggcg gggaaggagg agcgctaggt 50

 cggtgtacga ccgagattag ggtgcgtgcc agctccggga ggccgcggtg 100

 aggggccggg cccaagctgc cgacccgagc cgatcgtcag ggtcgccagc 150

 gcctcagctc tgtggaggag cagcagtagt cggagggtgc aggatattag 200

 aaatggctac tccccagtca attttcatct ttgcaatctg cattttaatg 250

 ataacagaat taattctggc ctcaaaaagc tactatgata tcttaggtgt 300

 gccaaaatcg gcatcagagc gccaaatcaa gaaggccttt cacaagttgg 350

 ccatgaagta ccaccctgac aaaaataaga gcccggatgc tgaagcaaaa 400

 ttcagagaga ttgcagaagc atatgaaaca ctctcagatg ctaatagacg 450

 aaaagagtat gatacacttg gacacagtgc ttttactagt ggtaaaggac 500

 aaagaggtag tggaagttct tttgagcagt catttaactt caattttgat 550

 gacttattta aagactttgg cttttttggt caaaaccaaa acactggatc 600

 caagaagcgt tttgaaaatc atttccagac acgccaggat ggtggttcca 650

 gtagacaaag gcatcatttc caagaatttt cttttggagg tggattattt 700

 gatgacatgt ttgaagatat ggagaaaatg ttttctttta gtggttttga 750

 ctctaccaat cagcatacag tacagactga aaatagattt catggatcta 800

 gcaagcactg caggactgtc actcaacgaa gaggaaatat ggttactaca 850

 tacactgact gttcaggaca gtagttctta ttctattctc actaaatcca 900

 actggttgac tcttcctcat tatctttgat gctaaacaat tttctgtgaa 950

 ctattttgac aagtgcatga tttcacttta aacaatttga tatagctatt 1000

 aaatatattt aagggttttt tttttttgac aaattcaaca ttcaacgagt 1050

 agacaaaatg ctaattattt ccctgattag gaaagtttct ttaaaaaaca 1100

 cgtaattttg cctagtgctt tttctctacc tgcccttggg ctcactaata 1150

 tcaccagtat tattaccaag aaaatattga gtttacctga ttaaacttta 1200

 aaagttaatt gtagatttaa attgtgtgaa cctaatgatt tttgcagtga 1250

 aacctttact aattcaaagt tgcatgttct atgacatctg tgacttgcgt 1300

 tgcagagtgt acatgaaact gtataattga gtcattcagt aaaggagaac 1350

 agtatcttgg ttaattgcta ctgaaaggtt gagaaaggaa tggtttgata 1400

 tttaccacag cgctgtgcct ttctacagta gaactggggt aaaggaaatg 1450

 gttttattgc ccatagtcat ttaggctgga aaaaagttga aaacttaacg 1500

 aaatattgcc aagagattgt tatgtgtttg gttccagcct aaaaatgatt 1550

 ttgtagtgtt gaaatcatag ctacttacat agctttttca tatttctttc 1600

 ttagttgttg gcactcttag gtcttagtat ggatttatgt gtttgtgtgt 1650

 gtgtagttta tcctctctct catctttatc tagagattga ctgatacctc 1700

 attctgtttg taaaaccagc cagtaatttc tgtgcaacct tactatgtgc 1750

 aatattttta aatcctgaga aatgtgtgct tttgttttcg gatagactta 1800

 tttctttagt tctgcacttt tccacattat actccatatg agtattaatc 1850

 ctatggatac atattaaaac aagtgtctca tacaacattg tatgtgagag 1900

 aaatataaat atttacaacc tgatattcgt tgttgtttta ttgttaaaag 1950

 tttattatgc aactctggag gtatagaggg catataagct atgggacata 2000

 tgctgatcac aggctatatt catgaagtta cttttgacca acctgaaaac 2050

 tgataggatt ttgtttgtca tttggtaatt tctactgcat tcttaccatc 2100

 cttctctcac aaattttgat agcttgaaga tctttttaat tataattttg 2150

 ttgtatttgt ttcctaggag caagtgttcc tgctgccagt tctttcctct 2200

 ttaggcgtgg ttgagaaaaa gcagaaactt tacataaagc tgtatttctt 2250

 aatcatcttt aatttgaaac ttaagaaaat gaatttattc tgttatattt 2300

 atgtaactta tttcctggaa gttatatcta ctagttttgt ttgataataa 2350

 taaaattagc tataccttga a 2371

<210> 728
<211> 223
<212> PRT
<213> Homo sapien

<400> 728
 Met Ala Thr Pro Gln Ser Ile Phe Ile Phe Ala Ile Cys Ile Leu
   1               5                  10                  15

 Met Ile Thr Glu Leu Ile Leu Ala Ser Lys Ser Tyr Tyr Asp Ile
                  20                  25                  30

 Leu Gly Val Pro Lys Ser Ala Ser Glu Arg Gln Ile Lys Lys Ala
                  35                  40                  45

 Phe His Lys Leu Ala Met Lys Tyr His Pro Asp Lys Asn Lys Ser
                  50                  55                  60

 Pro Asp Ala Glu Ala Lys Phe Arg Glu Ile Ala Glu Ala Tyr Glu
                  65                  70                  75

 Thr Leu Ser Asp Ala Asn Arg Arg Lys Glu Tyr Asp Thr Leu Gly
                  80                  85                  90

 His Ser Ala Phe Thr Ser Gly Lys Gly Gln Arg Gly Ser Gly Ser
                  95                 100                 105

 Ser Phe Glu Gln Ser Phe Asn Phe Asn Phe Asp Asp Leu Phe Lys
                 110                 115                 120

 Asp Phe Gly Phe Phe Gly Gln Asn Gln Asn Thr Gly Ser Lys Lys
                 125                 130                 135

 Arg Phe Glu Asn His Phe Gln Thr Arg Gln Asp Gly Gly Ser Ser
                 140                 145                 150

 Arg Gln Arg His His Phe Gln Glu Phe Ser Phe Gly Gly Gly Leu
                 155                 160                 165

 Phe Asp Asp Met Phe Glu Asp Met Glu Lys Met Phe Ser Phe Ser
                 170                 175                 180

 Gly Phe Asp Ser Thr Asn Gln His Thr Val Gln Thr Glu Asn Arg
                 185                 190                 195

 Phe His Gly Ser Ser Lys His Cys Arg Thr Val Thr Gln Arg Arg
                 200                 205                 210

 Gly Asn Met Val Thr Thr Tyr Thr Asp Cys Ser Gly Gln
                 215                 220

<210> 729
<211> 2165
<212> DNA
<213> Homo sapien

<400> 729
 cccgccttcc atacctcccc ggctccgctc ggttcctggc caccccgcag 50

 cccctgccca ggtgccatgg ccgcattgta ccgccctggc ctgcggctta 100

 actggcatgg gctgagcccc ttgggctggc catcatgccg tagcatccag 150

 accctgcgag tgcttagtgg agatctgggc cagcttccca ctggcattcg 200

 agattttgta gagcacagtg cccgcctgtg ccaaccagag ggcatccaca 250

 tctgtgatgg aactgaggct gagaatactg ccacactgac cctgctggag 300

 cagcagggcc tcatccgaaa gctccccaag tacaataact gctggctggc 350

 ccgcacagac cccaaggatg tggcacgagt agagagcaag acggtgattg 400

 taactccttc tcagcgggac acggtaccac tcccgcctgg tggggcctgt 450

 gggcagctgg gcaactggat gtccccagct gatttccagc gagctgtgga 500

 tgagaggttt ccaggctgca tgcagggccg caccatgtat gtgcttccat 550

 tcagcatggg tcctgtgggc tccccgctgt cccgcatcgg ggtgcagctc 600

 actgactcag cctatgtggt ggcaagcatg cgtattatga cccgactggg 650

 gacacctgtg cttcaggccc tgggagatgg tgactttgtc aagtgtctgc 700

 actccgtggg ccagcccctg acaggacaag gggagccagt gagccagtgg 750

 ccgtgcaacc cagagaaaac cctgattggc cacgtgcccg accagcggga 800

 gatcatctcc ttcggcagcg gctatggtgg caactccctg ctgggcaaga 850

 agtgctttgc cctacgcatc gcctctcggc tggcccggga tgagggctgg 900

 ctggcagagc acatgctgat cctgggcatc accagccctg cagggaagaa 950

 ggcgctatgt gcagccgcct tccctagtgc ctgtggcaag accaacctgg 1000

 ctatgatgcg gcctgcactg ccaggctgga aagtggagtg tgtgggggat 1050

 gatattgctt ggatgaggtt tgacagtgaa ggtcgactcc gggccatcaa 1100

 ccctgagaac ggcttctttg gggttgcccc tggtacctct gccaccacca 1150

 atcccaacgc catggctaca atccagagta acactatttt taccaatgtg 1200

 gctgagacca gtgatggtgg cgtgtactgg gagggcattg accagcctct 1250

 tccacctggt gttactgtga cctcctggct gggcaaaccc tggaaacctg 1300

 gtgacaagga gccctgtgca catcccaact ctcgattttg tgccccggct 1350

 cgccagtgcc ccatcatgga cccagcctgg gaggccccag agggtgtccc 1400

 cattgacgcc atcatctttg gtggccgcag acccaaaggg gtacccctgg 1450

 tatacgaggc cttcaactgg cgtcatgggg tgtttgtggg cagagccatg 1500

 cgctctgagt ccactgctgc agcagaacac aaagggaaga tcatcatgca 1550

 cgacccattt gccatgcggc ccttttttgg ctacaacttc gggcactacc 1600

 tggaacactg gctgagcatg gaagggcgca agggggccca gctgccccgt 1650

 atcttccatg tcaactggtt ccggcgtgac gaggcagggc acttcctgtg 1700

 gccaggcttt ggggagaatg ctcgggtgct agactggatc tgccggcggt 1750

 tagaggggga ggacagtgcc cgagagacac ccattgggct ggtgccaaag 1800

 gaaggagcct tggatctcag cggcctcaga gctatagaca ccactcagct 1850

 gttctccctc cccaaggact tctgggaaca ggaggttcgt gacattcgga 1900

 gctacctgac agagcaggtc aaccaggatc tgcccaaaga ggtgttggct 1950

 gagcttgagg ccctggagag acgtgtgcac aaaatgtgac ctgaggccta 2000

 gtctagcaag aggacatagc accctcatct gggaataggg aaggcacctt 2050

 gcagaaaata tgagcaattg atattaacta acatcttcaa tgtgccatag 2100

 accttcccac aaagactgtc caataataag agatgcttat ctattttaaa 2150

 aaaaaaaaaa aaaaa 2165

<210> 730
<211> 640
<212> PRT
<213> Homo sapien

<400> 730
 Met Ala Ala Leu Tyr Arg Pro Gly Leu Arg Leu Asn Trp His Gly
   1               5                  10                  15

 Leu Ser Pro Leu Gly Trp Pro Ser Cys Arg Ser Ile Gln Thr Leu
                  20                  25                  30

 Arg Val Leu Ser Gly Asp Leu Gly Gln Leu Pro Thr Gly Ile Arg
                  35                  40                  45

 Asp Phe Val Glu His Ser Ala Arg Leu Cys Gln Pro Glu Gly Ile
                  50                  55                  60

 His Ile Cys Asp Gly Thr Glu Ala Glu Asn Thr Ala Thr Leu Thr
                  65                  70                  75

 Leu Leu Glu Gln Gln Gly Leu Ile Arg Lys Leu Pro Lys Tyr Asn
                  80                  85                  90

 Asn Cys Trp Leu Ala Arg Thr Asp Pro Lys Asp Val Ala Arg Val
                  95                 100                 105

 Glu Ser Lys Thr Val Ile Val Thr Pro Ser Gln Arg Asp Thr Val
                 110                 115                 120

 Pro Leu Pro Pro Gly Gly Ala Cys Gly Gln Leu Gly Asn Trp Met
                 125                 130                 135

 Ser Pro Ala Asp Phe Gln Arg Ala Val Asp Glu Arg Phe Pro Gly
                 140                 145                 150

 Cys Met Gln Gly Arg Thr Met Tyr Val Leu Pro Phe Ser Met Gly
                 155                 160                 165

 Pro Val Gly Ser Pro Leu Ser Arg Ile Gly Val Gln Leu Thr Asp
                 170                 175                 180

 Ser Ala Tyr Val Val Ala Ser Met Arg Ile Met Thr Arg Leu Gly
                 185                 190                 195

 Thr Pro Val Leu Gln Ala Leu Gly Asp Gly Asp Phe Val Lys Cys
                 200                 205                 210

 Leu His Ser Val Gly Gln Pro Leu Thr Gly Gln Gly Glu Pro Val
                 215                 220                 225

 Ser Gln Trp Pro Cys Asn Pro Glu Lys Thr Leu Ile Gly His Val
                 230                 235                 240

 Pro Asp Gln Arg Glu Ile Ile Ser Phe Gly Ser Gly Tyr Gly Gly
                 245                 250                 255

 Asn Ser Leu Leu Gly Lys Lys Cys Phe Ala Leu Arg Ile Ala Ser
                 260                 265                 270

 Arg Leu Ala Arg Asp Glu Gly Trp Leu Ala Glu His Met Leu Ile
                 275                 280                 285

 Leu Gly Ile Thr Ser Pro Ala Gly Lys Lys Ala Leu Cys Ala Ala
                 290                 295                 300

 Ala Phe Pro Ser Ala Cys Gly Lys Thr Asn Leu Ala Met Met Arg
                 305                 310                 315

 Pro Ala Leu Pro Gly Trp Lys Val Glu Cys Val Gly Asp Asp Ile
                 320                 325                 330

 Ala Trp Met Arg Phe Asp Ser Glu Gly Arg Leu Arg Ala Ile Asn
                 335                 340                 345

 Pro Glu Asn Gly Phe Phe Gly Val Ala Pro Gly Thr Ser Ala Thr
                 350                 355                 360

 Thr Asn Pro Asn Ala Met Ala Thr Ile Gln Ser Asn Thr Ile Phe
                 365                 370                 375

 Thr Asn Val Ala Glu Thr Ser Asp Gly Gly Val Tyr Trp Glu Gly
                 380                 385                 390

 Ile Asp Gln Pro Leu Pro Pro Gly Val Thr Val Thr Ser Trp Leu
                 395                 400                 405

 Gly Lys Pro Trp Lys Pro Gly Asp Lys Glu Pro Cys Ala His Pro
                 410                 415                 420

 Asn Ser Arg Phe Cys Ala Pro Ala Arg Gln Cys Pro Ile Met Asp
                 425                 430                 435

 Pro Ala Trp Glu Ala Pro Glu Gly Val Pro Ile Asp Ala Ile Ile
                 440                 445                 450

 Phe Gly Gly Arg Arg Pro Lys Gly Val Pro Leu Val Tyr Glu Ala
                 455                 460                 465

 Phe Asn Trp Arg His Gly Val Phe Val Gly Arg Ala Met Arg Ser
                 470                 475                 480

 Glu Ser Thr Ala Ala Ala Glu His Lys Gly Lys Ile Ile Met His
                 485                 490                 495

 Asp Pro Phe Ala Met Arg Pro Phe Phe Gly Tyr Asn Phe Gly His
                 500                 505                 510

 Tyr Leu Glu His Trp Leu Ser Met Glu Gly Arg Lys Gly Ala Gln
                 515                 520                 525

 Leu Pro Arg Ile Phe His Val Asn Trp Phe Arg Arg Asp Glu Ala
                 530                 535                 540

 Gly His Phe Leu Trp Pro Gly Phe Gly Glu Asn Ala Arg Val Leu
                 545                 550                 555

 Asp Trp Ile Cys Arg Arg Leu Glu Gly Glu Asp Ser Ala Arg Glu
                 560                 565                 570

 Thr Pro Ile Gly Leu Val Pro Lys Glu Gly Ala Leu Asp Leu Ser
                 575                 580                 585

 Gly Leu Arg Ala Ile Asp Thr Thr Gln Leu Phe Ser Leu Pro Lys
                 590                 595                 600

 Asp Phe Trp Glu Gln Glu Val Arg Asp Ile Arg Ser Tyr Leu Thr
                 605                 610                 615

 Glu Gln Val Asn Gln Asp Leu Pro Lys Glu Val Leu Ala Glu Leu
                 620                 625                 630

 Glu Ala Leu Glu Arg Arg Val His Lys Met
                 635                 640

<210> 731
<211> 3423
<212> DNA
<213> Homo sapien

<400> 731
 cggctcgctg gtaccggcag tgccatggcg gccttcagca agtacttgac 50

 ggcgcggaac tcctcgctgg ctggtgccgc gttcctgctg ctctgcctgc 100

 tccacaagcg gcgccgcgcc ctcggcctgc acggtaagaa aagtggaaaa 150

 ccaccattac agaacaatga gaaagagggg aaaaaagagc gagctgtggt 200

 ggacaaggtg tttttctcaa ggctcataca gattctgaaa atcatggtcc 250

 ctagaacatt ttgtaaagag acaggttact tggtacttat tgctgttatg 300

 ctggtgtctc gaacatattg tgatgtttgg atgattcaaa atgggacact 350

 aattgaaagt ggtatcattg gtcgtagcag gaaagatttc aagagatact 400

 tactcaactt catcgctgcc atgcctctta tctctctggt taataacttc 450

 ttgaagtatg ggttaaatga gcttaaactg tgcttccgag taaggctcac 500

 taaatacctc tatgaggagt atcttcaagc tttcacatat tataaaatgg 550

 ggaatctgga caacagaata gctaatccag accagctgct tacacaagat 600

 gtagaaaaat tttgtaacag tgtagtcgat ctgtattcaa atcttagtaa 650

 gccattttta gacatagttt tgtatatctt taagttaacg agtgcaattg 700

 gagctcaggg cccagcgagc atgatggcct acttggttgt ttctgggcta 750

 ttcctaactc gacttcgaag acccattggt aagatgacaa taactgagca 800

 aaagtatgaa ggagaatata gatatgttaa ttctcggctc atcacaaaca 850

 gtgaagaaat tgccttttac aatgggaata aaagagaaaa gcagacagtc 900

 cactcagtct tccgaaaact ggtggaacac ctacataatt tcattttgtt 950

 tcggttttca atgggcttca ttgatagtat tattgccaaa taccttgcca 1000

 ctgttgttgg ttacctagtt gtcagtcgcc ctttcttaga tttgtctcat 1050

 cctcgacatc tcaagagtac acattcggaa cttctagagg attactacca 1100

 aagtggaaga atgcttttgc gaatgtctca agctctgggt cgaatagttt 1150

 tggctgggcg tgaaatgact agattggccg gttttactgc tcggattaca 1200

 gaattaatgc aagtactgaa ggatttaaat catggcaaat atgagcgcac 1250

 aatggtctca caacaggaaa agggtattga aggagtacaa gtcattccct 1300

 tgatacctgg tgctggagaa atcattattg cagataacat tataaagttt 1350

 gatcatgttc ctttagcaac gccaaatgga gatgttttga tccgagacct 1400

 taattttgaa gttcgatctg gggctaatgt tctaatttgt ggtccaaatg 1450

 gctgcggaaa gagttcactt ttccgtgttc ttggtgaatt atggcctctt 1500

 tttggaggac gtctaactaa acctgaaaga ggaaaattat tttatgttcc 1550

 tcagagacct tacatgaccc ttggaacact tcgagatcaa gtgatatatc 1600

 cagatggacg agaagatcag aaaaggaagg gaatttctga cctagtactg 1650

 aaggaatact tagacaatgt ccagttgggt catatccttg aacgtgaagg 1700

 aggctgggac agtgttcagg attggatgga cgtactcagt ggtggagaaa 1750

 agcaaagaat ggcgatggca agattatttt atcataaacc ccagtttgcc 1800

 attttggatg aatgcacaag tgcagttagt gtcgacgtgg aaggctacat 1850

 ttatagtcat tgtcgaaagg ttggcatcac tctcttcact gtgtctcata 1900

 ggaaatctct ttggaaacat catgagtact acctgcatat ggatggcaga 1950

 ggcaactatg aattcaaaca gataacagaa gatacagttg agtttggctc 2000

 ttagagaaat ctggagaact atacctgctt cagtgaaata attacagaat 2050

 atacttagaa aggcaaagta cattgtaaaa taaagttgag cttagttttt 2100

 tttaaaaaaa aaaaacaaag caacaaatta actagataca gaataatgga 2150

 gaacaagttg ttaaaacatt taatattata taggatattg ctaattgtgt 2200

 atatgttggt ttaattaata atatgtacta agaatgtcct tattcttgtg 2250

 gttaaaaacc tgcctaaatt aaattgggct tcaatcactg taacctgatt 2300

 catcctggga tgtaaaccat tcgaagtcag ctaattggac ttttatggct 2350

 ctatcttttc cttcagtgaa gaaccctatt taaaactggg tcatcatttg 2400

 tcctgttcta gcaagatagt cttcagtttc attttcctgt gccctgtggt 2450

 agttggaaac aaatcataat gtattattta aatgtttaac atcattgcat 2500

 aacagcgttt attatacagt ggcagatttc tttagctgcc acagtaatac 2550

 tcattccttg tgtgtgtctt ggagtgcatt tgactccagg aaaagccatt 2600

 ttggttttcc ttaactaaat gataaatgta cccctctcag tctgcagtat 2650

 tgagttgttt aaagtatatg tgcagtcttg cttacaagga ggggttacca 2700

 tgtatcacac ctaatcttcc caatgtttgg gatattaaaa cacaaagtcc 2750

 ttaacatgcc aggctcaagg tcttataaga gttctagatt tttaagagaa 2800

 ttagacaaat ttgtgtgtgt tagaagccca ttcattagaa gtgtggtggt 2850

 tatttggtat taaactccaa atgagccata ggaaggcact acatgaaata 2900

 atgcactgag tatgcaatgc tatcactgtc tttgactgtg attttatgtt 2950

 taaaaagtat gttctaaaat tattatatat acatgggtga attatgtttc 3000

 cgaggcactg ttttatctct gtgaatcttg aataactttt ttatatttgg 3050

 gttatgatgt caaacgatcc taagcgaaga tgatttcagt tcatcaaatc 3100

 atcattaatg actttatgta ttatttgcac agggagaatt gaaactgagt 3150

 ataatcaata agctagatac gaaatcagtt tctcaaactg agcttcagaa 3200

 aggggcattt tgtactcttg tttttgcata actggttttg tttttttgca 3250

 gaattaacta taacaatcac tggctaccga agtaaactga tgtactgaat 3300

 tccataatac ataacattca atttttacca cttctgttta gcgaacttgt 3350

 atacttattt tctgttcaga ttaaaaaaaa aaaaaaaaaa aactcagata 3400

 tcctataaaa aaaaaaggaa ttc 3423

<210> 732
<211> 659
<212> PRT
<213> Homo sapien

<400> 732
 Met Ala Ala Phe Ser Lys Tyr Leu Thr Ala Arg Asn Ser Ser Leu
   1               5                  10                  15

 Ala Gly Ala Ala Phe Leu Leu Leu Cys Leu Leu His Lys Arg Arg
                  20                  25                  30

 Arg Ala Leu Gly Leu His Gly Lys Lys Ser Gly Lys Pro Pro Leu
                  35                  40                  45

 Gln Asn Asn Glu Lys Glu Gly Lys Lys Glu Arg Ala Val Val Asp
                  50                  55                  60

 Lys Val Phe Phe Ser Arg Leu Ile Gln Ile Leu Lys Ile Met Val
                  65                  70                  75

 Pro Arg Thr Phe Cys Lys Glu Thr Gly Tyr Leu Val Leu Ile Ala
                  80                  85                  90

 Val Met Leu Val Ser Arg Thr Tyr Cys Asp Val Trp Met Ile Gln
                  95                 100                 105

 Asn Gly Thr Leu Ile Glu Ser Gly Ile Ile Gly Arg Ser Arg Lys
                 110                 115                 120

 Asp Phe Lys Arg Tyr Leu Leu Asn Phe Ile Ala Ala Met Pro Leu
                 125                 130                 135

 Ile Ser Leu Val Asn Asn Phe Leu Lys Tyr Gly Leu Asn Glu Leu
                 140                 145                 150

 Lys Leu Cys Phe Arg Val Arg Leu Thr Lys Tyr Leu Tyr Glu Glu
                 155                 160                 165

 Tyr Leu Gln Ala Phe Thr Tyr Tyr Lys Met Gly Asn Leu Asp Asn
                 170                 175                 180

 Arg Ile Ala Asn Pro Asp Gln Leu Leu Thr Gln Asp Val Glu Lys
                 185                 190                 195

 Phe Cys Asn Ser Val Val Asp Leu Tyr Ser Asn Leu Ser Lys Pro
                 200                 205                 210

 Phe Leu Asp Ile Val Leu Tyr Ile Phe Lys Leu Thr Ser Ala Ile
                 215                 220                 225

 Gly Ala Gln Gly Pro Ala Ser Met Met Ala Tyr Leu Val Val Ser
                 230                 235                 240

 Gly Leu Phe Leu Thr Arg Leu Arg Arg Pro Ile Gly Lys Met Thr
                 245                 250                 255

 Ile Thr Glu Gln Lys Tyr Glu Gly Glu Tyr Arg Tyr Val Asn Ser
                 260                 265                 270

 Arg Leu Ile Thr Asn Ser Glu Glu Ile Ala Phe Tyr Asn Gly Asn
                 275                 280                 285

 Lys Arg Glu Lys Gln Thr Val His Ser Val Phe Arg Lys Leu Val
                 290                 295                 300

 Glu His Leu His Asn Phe Ile Leu Phe Arg Phe Ser Met Gly Phe
                 305                 310                 315

 Ile Asp Ser Ile Ile Ala Lys Tyr Leu Ala Thr Val Val Gly Tyr
                 320                 325                 330

 Leu Val Val Ser Arg Pro Phe Leu Asp Leu Ser His Pro Arg His
                 335                 340                 345

 Leu Lys Ser Thr His Ser Glu Leu Leu Glu Asp Tyr Tyr Gln Ser
                 350                 355                 360

 Gly Arg Met Leu Leu Arg Met Ser Gln Ala Leu Gly Arg Ile Val
                 365                 370                 375

 Leu Ala Gly Arg Glu Met Thr Arg Leu Ala Gly Phe Thr Ala Arg
                 380                 385                 390

 Ile Thr Glu Leu Met Gln Val Leu Lys Asp Leu Asn His Gly Lys
                 395                 400                 405

 Tyr Glu Arg Thr Met Val Ser Gln Gln Glu Lys Gly Ile Glu Gly
                 410                 415                 420

 Val Gln Val Ile Pro Leu Ile Pro Gly Ala Gly Glu Ile Ile Ile
                 425                 430                 435

 Ala Asp Asn Ile Ile Lys Phe Asp His Val Pro Leu Ala Thr Pro
                 440                 445                 450

 Asn Gly Asp Val Leu Ile Arg Asp Leu Asn Phe Glu Val Arg Ser
                 455                 460                 465

 Gly Ala Asn Val Leu Ile Cys Gly Pro Asn Gly Cys Gly Lys Ser
                 470                 475                 480

 Ser Leu Phe Arg Val Leu Gly Glu Leu Trp Pro Leu Phe Gly Gly
                 485                 490                 495

 Arg Leu Thr Lys Pro Glu Arg Gly Lys Leu Phe Tyr Val Pro Gln
                 500                 505                 510

 Arg Pro Tyr Met Thr Leu Gly Thr Leu Arg Asp Gln Val Ile Tyr
                 515                 520                 525

 Pro Asp Gly Arg Glu Asp Gln Lys Arg Lys Gly Ile Ser Asp Leu
                 530                 535                 540

 Val Leu Lys Glu Tyr Leu Asp Asn Val Gln Leu Gly His Ile Leu
                 545                 550                 555

 Glu Arg Glu Gly Gly Trp Asp Ser Val Gln Asp Trp Met Asp Val
                 560                 565                 570

 Leu Ser Gly Gly Glu Lys Gln Arg Met Ala Met Ala Arg Leu Phe
                 575                 580                 585

 Tyr His Lys Pro Gln Phe Ala Ile Leu Asp Glu Cys Thr Ser Ala
                 590                 595                 600

 Val Ser Val Asp Val Glu Gly Tyr Ile Tyr Ser His Cys Arg Lys
                 605                 610                 615

 Val Gly Ile Thr Leu Phe Thr Val Ser His Arg Lys Ser Leu Trp
                 620                 625                 630

 Lys His His Glu Tyr Tyr Leu His Met Asp Gly Arg Gly Asn Tyr
                 635                 640                 645

 Glu Phe Lys Gln Ile Thr Glu Asp Thr Val Glu Phe Gly Ser
                 650                 655

<210> 733
<211> 1982
<212> DNA
<213> Homo sapien

<400> 733
 ggcgagaggc gggctgaggc ggcccagcgg cggcaggtga ggcggaacca 50

 accctcctgg ccatgggagg ggccgtggtg gacgagggcc ccacaggcgt 100

 caaggcccct gacggcggct ggggctgggc cgtgctcttc ggctgtttcg 150

 tcatcactgg cttctcctac gccttcccca aggccgtcag tgtcttcttc 200

 aaggagctca tacaggagtt tgggatcggc tacagcgaca cagcctggat 250

 ctcctccatc ctgctggcca tgctctacgg gacaggtccg ctctgcagtg 300

 tgtgcgtgaa ccgctttggc tgccggcccg tcatgcttgt ggggggtctc 350

 tttgcgtcgc tgggcatggt ggctgcgtcc ttttgccgga gcatcatcca 400

 ggtctacctc accactgggg tcatcacggg gttgggtttg gcactcaact 450

 tccagccctc gctcatcatg ctgaaccgct acttcagcaa gcggcgcccc 500

 atggccaacg ggctggcggc agcaggtagc cctgtcttcc tgtgtgccct 550

 gagcccgctg gggcagctgc tgcaggaccg ctacggctgg cggggcggct 600

 tcctcatcct gggcggcctg ctgctcaact gctgcgtgtg tgccgcactc 650

 atgaggcccc tggtggtcac ggcccagccg ggctcggggc cgccgcgacc 700

 ctcccggcgc ctgctagacc tgagcgtctt ccgggaccgc ggctttgtgc 750

 tttacgccgt ggccgcctcg gtcatggtgc tggggctctt cgtcccgccc 800

 gtgttcgtgg tgagctacgc caaggacctg ggcgtgcccg acaccaaggc 850

 cgccttcctg ctcaccatcc tgggcttcat tgacatcttc gcgcggccgg 900

 ccgcgggctt cgtggcgggg cttgggaagg tgcggcccta ctccgtctac 950

 ctcttcagct tctccatgtt cttcaacggc ctcgcggacc tggcgggctc 1000

 tacggcgggc gactacggcg gcctcgtggt cttctgcatc ttctttggca 1050

 tctcctacgg catggtgggg gccctgcagt tcgaggtgct catggccatc 1100

 gtgggcaccc acaagttctc cagtgccatt ggcctggtgc tgctgatgga 1150

 ggcggtggcc gtgctcgtcg ggcccccttc gggaggcaaa ctcctggatg 1200

 cgacccacgt ctacatgtac gtgttcatcc tggcgggggc cgaggtgctc 1250

 acctcctccc tgattttgct gctgggcaac ttcttctgca ttaggaagaa 1300

 gcccaaagag ccacagcctg aggtggcggc cgcggaggag gagaagctcc 1350

 acaagcctcc tgcagactcg ggggtggact tgcgggaggt ggagcatttc 1400

 ctgaaggctg agcctgagaa aaacggggag gtggttcaca ccccggaaac 1450

 aagtgtctga gtggctgggc ggggccggca ggcacaggga ggaggtacag 1500

 aagccggcaa cgcttgctat ttattttaca aactggactg gctcaggcag 1550

 ggccacggct gggctccagc tgccggccca gcggatcgtc gcccgatcag 1600

 tgttttgagg gggaaggtgg cggggtggga accgtgtcat tccagagtgg 1650

 atctgcggtg aagccaagcc gcaaggttac aaggcatcct caccaggggc 1700

 cccgcctgct gctcccaggt ggcctgcggc cactgctatg ctcaaggacc 1750

 tggaaaccca tgcttcgaga caacgtgact ttaatgggag ggtgggtggg 1800

 ccgcagacag gctggcaggg caggtgctgc gtggggccct ctccagcccg 1850

 tcctaccctg ggctcacatg gggcctgtgc ccacccctct tgagtgtctt 1900

 ggggacagct ctttccaccc ctggaagatg gaaataaacc tgcgtgtggg 1950

 tggagtgttc tcgtgccgaa ttcaaaaagc tt 1982

<210> 734
<211> 465
<212> PRT
<213> Homo sapien

<400> 734
 Met Gly Gly Ala Val Val Asp Glu Gly Pro Thr Gly Val Lys Ala
   1               5                  10                  15

 Pro Asp Gly Gly Trp Gly Trp Ala Val Leu Phe Gly Cys Phe Val
                  20                  25                  30

 Ile Thr Gly Phe Ser Tyr Ala Phe Pro Lys Ala Val Ser Val Phe
                  35                  40                  45

 Phe Lys Glu Leu Ile Gln Glu Phe Gly Ile Gly Tyr Ser Asp Thr
                  50                  55                  60

 Ala Trp Ile Ser Ser Ile Leu Leu Ala Met Leu Tyr Gly Thr Gly
                  65                  70                  75

 Pro Leu Cys Ser Val Cys Val Asn Arg Phe Gly Cys Arg Pro Val
                  80                  85                  90

 Met Leu Val Gly Gly Leu Phe Ala Ser Leu Gly Met Val Ala Ala
                  95                 100                 105

 Ser Phe Cys Arg Ser Ile Ile Gln Val Tyr Leu Thr Thr Gly Val
                 110                 115                 120

 Ile Thr Gly Leu Gly Leu Ala Leu Asn Phe Gln Pro Ser Leu Ile
                 125                 130                 135

 Met Leu Asn Arg Tyr Phe Ser Lys Arg Arg Pro Met Ala Asn Gly
                 140                 145                 150

 Leu Ala Ala Ala Gly Ser Pro Val Phe Leu Cys Ala Leu Ser Pro
                 155                 160                 165

 Leu Gly Gln Leu Leu Gln Asp Arg Tyr Gly Trp Arg Gly Gly Phe
                 170                 175                 180

 Leu Ile Leu Gly Gly Leu Leu Leu Asn Cys Cys Val Cys Ala Ala
                 185                 190                 195

 Leu Met Arg Pro Leu Val Val Thr Ala Gln Pro Gly Ser Gly Pro
                 200                 205                 210

 Pro Arg Pro Ser Arg Arg Leu Leu Asp Leu Ser Val Phe Arg Asp
                 215                 220                 225

 Arg Gly Phe Val Leu Tyr Ala Val Ala Ala Ser Val Met Val Leu
                 230                 235                 240

 Gly Leu Phe Val Pro Pro Val Phe Val Val Ser Tyr Ala Lys Asp
                 245                 250                 255

 Leu Gly Val Pro Asp Thr Lys Ala Ala Phe Leu Leu Thr Ile Leu
                 260                 265                 270

 Gly Phe Ile Asp Ile Phe Ala Arg Pro Ala Ala Gly Phe Val Ala
                 275                 280                 285

 Gly Leu Gly Lys Val Arg Pro Tyr Ser Val Tyr Leu Phe Ser Phe
                 290                 295                 300

 Ser Met Phe Phe Asn Gly Leu Ala Asp Leu Ala Gly Ser Thr Ala
                 305                 310                 315

 Gly Asp Tyr Gly Gly Leu Val Val Phe Cys Ile Phe Phe Gly Ile
                 320                 325                 330

 Ser Tyr Gly Met Val Gly Ala Leu Gln Phe Glu Val Leu Met Ala
                 335                 340                 345

 Ile Val Gly Thr His Lys Phe Ser Ser Ala Ile Gly Leu Val Leu
                 350                 355                 360

 Leu Met Glu Ala Val Ala Val Leu Val Gly Pro Pro Ser Gly Gly
                 365                 370                 375

 Lys Leu Leu Asp Ala Thr His Val Tyr Met Tyr Val Phe Ile Leu
                 380                 385                 390

 Ala Gly Ala Glu Val Leu Thr Ser Ser Leu Ile Leu Leu Leu Gly
                 395                 400                 405

 Asn Phe Phe Cys Ile Arg Lys Lys Pro Lys Glu Pro Gln Pro Glu
                 410                 415                 420

 Val Ala Ala Ala Glu Glu Glu Lys Leu His Lys Pro Pro Ala Asp
                 425                 430                 435

 Ser Gly Val Asp Leu Arg Glu Val Glu His Phe Leu Lys Ala Glu
                 440                 445                 450

 Pro Glu Lys Asn Gly Glu Val Val His Thr Pro Glu Thr Ser Val
                 455                 460                 465

<210> 735
<211> 1982
<212> DNA
<213> Homo sapien

<400> 735
 ggcgagaggc gggctgaggc ggcccagcgg cggcaggtga ggcggaacca 50

 accctcctgg ccatgggagg ggccgtggtg gacgagggcc ccacaggcgt 100

 caaggcccct gacggcggct ggggctgggc cgtgctcttc ggctgtttcg 150

 tcatcactgg cttctcctac gccttcccca aggccgtcag tgtcttcttc 200

 aaggagctca tacaggagtt tgggatcggc tacagcgaca cagcctggat 250

 ctcctccatc ctgctggcca tgctctacgg gacaggtccg ctctgcagtg 300

 tgtgcgtgaa ccgctttggc tgccggcccg tcatgcttgt ggggggtctc 350

 tttgcgtcgc tgggcatggt ggctgcgtcc ttttgccgga gcatcatcca 400

 ggtctacctc accactgggg tcatcacggg gttgggtttg gcactcaact 450

 tccagccctc gctcatcatg ctgaaccgct acttcagcaa gcggcgcccc 500

 atggccaacg ggctggcggc agcaggtagc cctgtcttcc tgtgtgccct 550

 gagcccgctg gggcagctgc tgcaggaccg ctacggctgg cggggcggct 600

 tcctcatcct gggcggcctg ctgctcaact gctgcgtgtg tgccgcactc 650

 atgaggcccc tggtggtcac ggcccagccg ggctcggggc cgccgcgacc 700

 ctcccggcgc ctgctagacc tgagcgtctt ccgggaccgc ggctttgtgc 750

 tttacgccgt ggccgcctcg gtcatggtgc tggggctctt cgtcccgccc 800

 gtgttcgtgg tgagctacgc caaggacctg ggcgtgcccg acaccaaggc 850

 cgccttcctg ctcaccatcc tgggcttcat tgacatcttc gcgcggccgg 900

 ccgcgggctt cgtggcgggg cttgggaagg tgcggcccta ctccgtctac 950

 ctcttcagct tctccatgtt cttcaacggc ctcgcggacc tggcgggctc 1000

 tacggcgggc gactacggcg gcctcgtggt cttctgcatc ttctttggca 1050

 tctcctacgg catggtgggg gccctgcagt tcgaggtgct catggccatc 1100

 gtgggcaccc acaagttctc cagtgccatt ggcctggtgc tgctgatgga 1150

 ggcggtggcc gtgctcgtcg ggcccccttc gggaggcaaa ctcctggatg 1200

 cgacccacgt ctacatgtac gtgttcatcc tggcgggggc cgaggtgctc 1250

 acctcctccc tgattttgct gctgggcaac ttcttctgca ttaggaagaa 1300

 gcccaaagag ccacagcctg aggtggcggc cgcggaggag gagaagctcc 1350

 acaagcctcc tgcagactcg ggggtggact tgcgggaggt ggagcatttc 1400

 ctgaaggctg agcctgagaa aaacggggag gtggttcaca ccccggaaac 1450

 aagtgtctga gtggctgggc ggggccggca ggcacaggga ggaggtacag 1500

 aagccggcaa cgcttgctat ttattttaca aactggactg gctcaggcag 1550

 ggccacggct gggctccagc tgccggccca gcggatcgtc gcccgatcag 1600

 tgttttgagg gggaaggtgg cggggtggga accgtgtcat tccagagtgg 1650

 atctgcggtg aagccaagcc gcaaggttac aaggcatcct caccaggggc 1700

 cccgcctgct gctcccaggt ggcctgcggc cactgctatg ctcaaggacc 1750

 tggaaaccca tgcttcgaga caacgtgact ttaatgggag ggtgggtggg 1800

 ccgcagacag gctggcaggg caggtgctgc gtggggccct ctccagcccg 1850

 tcctaccctg ggctcacatg gggcctgtgc ccacccctct tgagtgtctt 1900

 ggggacagct ctttccaccc ctggaagatg gaaataaacc tgcgtgtggg 1950

 tggagtgttc tcgtgccgaa ttcaaaaagc tt 1982

<210> 736
<211> 465
<212> PRT
<213> Homo sapien

<400> 736
 Met Gly Gly Ala Val Val Asp Glu Gly Pro Thr Gly Val Lys Ala
   1               5                  10                  15

 Pro Asp Gly Gly Trp Gly Trp Ala Val Leu Phe Gly Cys Phe Val
                  20                  25                  30

 Ile Thr Gly Phe Ser Tyr Ala Phe Pro Lys Ala Val Ser Val Phe
                  35                  40                  45

 Phe Lys Glu Leu Ile Gln Glu Phe Gly Ile Gly Tyr Ser Asp Thr
                  50                  55                  60

 Ala Trp Ile Ser Ser Ile Leu Leu Ala Met Leu Tyr Gly Thr Gly
                  65                  70                  75

 Pro Leu Cys Ser Val Cys Val Asn Arg Phe Gly Cys Arg Pro Val
                  80                  85                  90

 Met Leu Val Gly Gly Leu Phe Ala Ser Leu Gly Met Val Ala Ala
                  95                 100                 105

 Ser Phe Cys Arg Ser Ile Ile Gln Val Tyr Leu Thr Thr Gly Val
                 110                 115                 120

 Ile Thr Gly Leu Gly Leu Ala Leu Asn Phe Gln Pro Ser Leu Ile
                 125                 130                 135

 Met Leu Asn Arg Tyr Phe Ser Lys Arg Arg Pro Met Ala Asn Gly
                 140                 145                 150

 Leu Ala Ala Ala Gly Ser Pro Val Phe Leu Cys Ala Leu Ser Pro
                 155                 160                 165

 Leu Gly Gln Leu Leu Gln Asp Arg Tyr Gly Trp Arg Gly Gly Phe
                 170                 175                 180

 Leu Ile Leu Gly Gly Leu Leu Leu Asn Cys Cys Val Cys Ala Ala
                 185                 190                 195

 Leu Met Arg Pro Leu Val Val Thr Ala Gln Pro Gly Ser Gly Pro
                 200                 205                 210

 Pro Arg Pro Ser Arg Arg Leu Leu Asp Leu Ser Val Phe Arg Asp
                 215                 220                 225

 Arg Gly Phe Val Leu Tyr Ala Val Ala Ala Ser Val Met Val Leu
                 230                 235                 240

 Gly Leu Phe Val Pro Pro Val Phe Val Val Ser Tyr Ala Lys Asp
                 245                 250                 255

 Leu Gly Val Pro Asp Thr Lys Ala Ala Phe Leu Leu Thr Ile Leu
                 260                 265                 270

 Gly Phe Ile Asp Ile Phe Ala Arg Pro Ala Ala Gly Phe Val Ala
                 275                 280                 285

 Gly Leu Gly Lys Val Arg Pro Tyr Ser Val Tyr Leu Phe Ser Phe
                 290                 295                 300

 Ser Met Phe Phe Asn Gly Leu Ala Asp Leu Ala Gly Ser Thr Ala
                 305                 310                 315

 Gly Asp Tyr Gly Gly Leu Val Val Phe Cys Ile Phe Phe Gly Ile
                 320                 325                 330

 Ser Tyr Gly Met Val Gly Ala Leu Gln Phe Glu Val Leu Met Ala
                 335                 340                 345

 Ile Val Gly Thr His Lys Phe Ser Ser Ala Ile Gly Leu Val Leu
                 350                 355                 360

 Leu Met Glu Ala Val Ala Val Leu Val Gly Pro Pro Ser Gly Gly
                 365                 370                 375

 Lys Leu Leu Asp Ala Thr His Val Tyr Met Tyr Val Phe Ile Leu
                 380                 385                 390

 Ala Gly Ala Glu Val Leu Thr Ser Ser Leu Ile Leu Leu Leu Gly
                 395                 400                 405

 Asn Phe Phe Cys Ile Arg Lys Lys Pro Lys Glu Pro Gln Pro Glu
                 410                 415                 420

 Val Ala Ala Ala Glu Glu Glu Lys Leu His Lys Pro Pro Ala Asp
                 425                 430                 435

 Ser Gly Val Asp Leu Arg Glu Val Glu His Phe Leu Lys Ala Glu
                 440                 445                 450

 Pro Glu Lys Asn Gly Glu Val Val His Thr Pro Glu Thr Ser Val
                 455                 460                 465

<210> 737
<211> 1666
<212> DNA
<213> Homo sapien

<400> 737
 ctccataagg cacaaacttt cagagacagc agagcacaca agcttctagg 50

 acaagagcca ggaagaaacc accggaagga accatctcac tgtgtgtaaa 100

 catgacttcc aagctggccg tggctctctt ggcagccttc ctgatttctg 150

 cagctctgtg tgaaggtgca gttttgccaa ggagtgctaa agaacttaga 200

 tgtcagtgca taaagacata ctccaaacct ttccacccca aatttatcaa 250

 agaactgaga gtgattgaga gtggaccaca ctgcgccaac acagaaatta 300

 ttgtaaagct ttctgatgga agagagctct gtctggaccc caaggaaaac 350

 tgggtgcaga gggttgtgga gaagtttttg aagagggctg agaattcata 400

 aaaaaattca ttctctgtgg tatccaagaa tcagtgaaga tgccagtgaa 450

 acttcaagca aatctacttc aacacttcat gtattgtgtg ggtctgttgt 500

 agggttgcca gatgcaatac aagattcctg gttaaatttg aatttcagta 550

 aacaatgaat agtttttcat tgtaccatga aatatccaga acatacttat 600

 atgtaaagta ttatttattt gaatctacaa aaaacaacaa ataattttta 650

 aatataagga ttttcctaga tattgcacgg gagaatatac aaatagcaaa 700

 attgaggcca agggccaaga gaatatccga actttaattt caggaattga 750

 atgggtttgc tagaatgtga tatttgaagc atcacataaa aatgatggga 800

 caataaattt tgccataaag tcaaatttag ctggaaatcc tggatttttt 850

 tctgttaaat ctggcaaccc tagtctgcta gccaggatcc acaagtcctt 900

 gttccactgt gccttggttt ctcctttatt tctaagtgga aaaagtatta 950

 gccaccatct tacctcacag tgatgttgtg aggacatgtg gaagcacttt 1000

 aagttttttc atcataacat aaattatttt caagtgtaac ttattaacct 1050

 atttattatt tatgtattta tttaagcatc aaatatttgt gcaagaattt 1100

 ggaaaaatag aagatgaatc attgattgaa tagttataaa gatgttatag 1150

 taaatttatt ttattttaga tattaaatga tgttttatta gataaatttc 1200

 aatcagggtt tttagattaa acaaacaaac aattgggtac ccagttaaat 1250

 tttcatttca gataaacaac aaataatttt ttagtataag tacattattg 1300

 tttatctgaa attttaattg aactaacaat cctagtttga tactcccagt 1350

 cttgtcattg ccagctgtgt tggtagtgct gtgttgaatt acggaataat 1400

 gagttagaac tattaaaaca gccaaaactc cacagtcaat attagtaatt 1450

 tcttgctggt tgaaacttgt ttattatgta caaatagatt cttataatat 1500

 tatttaaatg actgcatttt taaatacaag gctttatatt tttaacttta 1550

 agatgttttt atgtgctctc caaatttttt ttactgtttc tgattgtatg 1600

 gaaatataaa agtaaatatg aaacatttaa aatataattt gttgtcaaag 1650

 taaaaaaaaa aaaaaa 1666

<210> 738
<211> 99
<212> PRT
<213> Homo sapien

<400> 738
 Met Thr Ser Lys Leu Ala Val Ala Leu Leu Ala Ala Phe Leu Ile
   1               5                  10                  15

 Ser Ala Ala Leu Cys Glu Gly Ala Val Leu Pro Arg Ser Ala Lys
                  20                  25                  30

 Glu Leu Arg Cys Gln Cys Ile Lys Thr Tyr Ser Lys Pro Phe His
                  35                  40                  45

 Pro Lys Phe Ile Lys Glu Leu Arg Val Ile Glu Ser Gly Pro His
                  50                  55                  60

 Cys Ala Asn Thr Glu Ile Ile Val Lys Leu Ser Asp Gly Arg Glu
                  65                  70                  75

 Leu Cys Leu Asp Pro Lys Glu Asn Trp Val Gln Arg Val Val Glu
                  80                  85                  90

 Lys Phe Leu Lys Arg Ala Glu Asn Ser
                  95

<210> 739
<211> 1447
<212> DNA
<213> Homo sapien

<400> 739
 agtcctgctc tccgcacgcc accttaggcc cgcagccgtg ccgggtgctc 50

 ttcagcatgt ccttcatccc ggtggccgag gattccgact tccccatcca 100

 caacctgccc tacggcgtct tctcgaccag aggcgaccca agaccgagga 150

 taggtgtggc cattggcgac cagatcctgg acctcagcat catcaagcac 200

 ctctttactg gtcctgtcct ctccaaacac caggatgtct tcaatcagcc 250

 tacactcaac agcttcatgg gcctgggtca ggctgcctgg aaggaggcga 300

 gagtgttctt gcagaacttg ctgtctgtga gccaagccag gctcagagat 350

 gacaccgaac ttcggaagtg tgcattcatc tcccaggctt ctgccacgat 400

 gcaccttcca gccaccatag gagactacac agacttctat tcctctcggc 450

 agcatgctac caacgtcgga atcatgttca gggacaagga gaatgcgttg 500

 atgccaaatt ggctgcactt accagtgggc taccatggcc gtgcctcctc 550

 tgtcgtggtg tctggcaccc caatccgaag gcccatggga cagatgaaac 600

 ctgatgactc taagcctccc gtatatggtg cctgcaagct cttggacatg 650

 gagctggaaa tggctttttt tgtaggccct ggaaacagat tgggagagcc 700

 gatccccatt tccaaggccc atgagcacat ttttggaatg gtccttatga 750

 acgactggag tgcacgagac attcagaagt gggagtatgt ccctctcggg 800

 ccattccttg ggaagagttt tgggaccact gtctctccgt gggtggtgcc 850

 catggatgct ctcatgccct ttgctgtgcc caacccgaag caggacccca 900

 ggcccctgcc gtatctgtgc catgacgagc cctacacatt tgacatcaac 950

 ctctctgtta acctgaaagg agaaggaatg agccaggcgg ctaccatatg 1000

 caagtccaat tttaagtaca tgtactggac gatgctgcag cagctcactc 1050

 accactctgt caacggctgc aacctgcggc cgggggacct cctggcttct 1100

 gggaccatca gcgggccgga gccagaaaac ttcggctcca tgttggaact 1150

 gtcgtggaag ggaacgaagc ccatagacct ggggaatggt cagaccagga 1200

 agtttctgct ggacggggat gaagtcatca taacagggta ctgccagggg 1250

 gatggttacc gcatcggctt tggccagtgt gctggaaaag tgctgcctgc 1300

 tctcctgcca tcatgagatt ttctctgctc ttctggaaac aaagggctca 1350

 agcacccctt tcaaccctgt gactggggtc ctccctcggg ctgtaggcct 1400

 ggtccgccat tcagtgacaa ataaagccat tgtgctctga ggcctgc 1447

<210> 740
<211> 419
<212> PRT
<213> Homo sapien

<400> 740
 Met Ser Phe Ile Pro Val Ala Glu Asp Ser Asp Phe Pro Ile His
   1               5                  10                  15

 Asn Leu Pro Tyr Gly Val Phe Ser Thr Arg Gly Asp Pro Arg Pro
                  20                  25                  30

 Arg Ile Gly Val Ala Ile Gly Asp Gln Ile Leu Asp Leu Ser Ile
                  35                  40                  45

 Ile Lys His Leu Phe Thr Gly Pro Val Leu Ser Lys His Gln Asp
                  50                  55                  60

 Val Phe Asn Gln Pro Thr Leu Asn Ser Phe Met Gly Leu Gly Gln
                  65                  70                  75

 Ala Ala Trp Lys Glu Ala Arg Val Phe Leu Gln Asn Leu Leu Ser
                  80                  85                  90

 Val Ser Gln Ala Arg Leu Arg Asp Asp Thr Glu Leu Arg Lys Cys
                  95                 100                 105

 Ala Phe Ile Ser Gln Ala Ser Ala Thr Met His Leu Pro Ala Thr
                 110                 115                 120

 Ile Gly Asp Tyr Thr Asp Phe Tyr Ser Ser Arg Gln His Ala Thr
                 125                 130                 135

 Asn Val Gly Ile Met Phe Arg Asp Lys Glu Asn Ala Leu Met Pro
                 140                 145                 150

 Asn Trp Leu His Leu Pro Val Gly Tyr His Gly Arg Ala Ser Ser
                 155                 160                 165

 Val Val Val Ser Gly Thr Pro Ile Arg Arg Pro Met Gly Gln Met
                 170                 175                 180

 Lys Pro Asp Asp Ser Lys Pro Pro Val Tyr Gly Ala Cys Lys Leu
                 185                 190                 195

 Leu Asp Met Glu Leu Glu Met Ala Phe Phe Val Gly Pro Gly Asn
                 200                 205                 210

 Arg Leu Gly Glu Pro Ile Pro Ile Ser Lys Ala His Glu His Ile
                 215                 220                 225

 Phe Gly Met Val Leu Met Asn Asp Trp Ser Ala Arg Asp Ile Gln
                 230                 235                 240

 Lys Trp Glu Tyr Val Pro Leu Gly Pro Phe Leu Gly Lys Ser Phe
                 245                 250                 255

 Gly Thr Thr Val Ser Pro Trp Val Val Pro Met Asp Ala Leu Met
                 260                 265                 270

 Pro Phe Ala Val Pro Asn Pro Lys Gln Asp Pro Arg Pro Leu Pro
                 275                 280                 285

 Tyr Leu Cys His Asp Glu Pro Tyr Thr Phe Asp Ile Asn Leu Ser
                 290                 295                 300

 Val Asn Leu Lys Gly Glu Gly Met Ser Gln Ala Ala Thr Ile Cys
                 305                 310                 315

 Lys Ser Asn Phe Lys Tyr Met Tyr Trp Thr Met Leu Gln Gln Leu
                 320                 325                 330

 Thr His His Ser Val Asn Gly Cys Asn Leu Arg Pro Gly Asp Leu
                 335                 340                 345

 Leu Ala Ser Gly Thr Ile Ser Gly Pro Glu Pro Glu Asn Phe Gly
                 350                 355                 360

 Ser Met Leu Glu Leu Ser Trp Lys Gly Thr Lys Pro Ile Asp Leu
                 365                 370                 375

 Gly Asn Gly Gln Thr Arg Lys Phe Leu Leu Asp Gly Asp Glu Val
                 380                 385                 390

 Ile Ile Thr Gly Tyr Cys Gln Gly Asp Gly Tyr Arg Ile Gly Phe
                 395                 400                 405

 Gly Gln Cys Ala Gly Lys Val Leu Pro Ala Leu Leu Pro Ser
                 410                 415

<210> 741
<211> 3579
<212> DNA
<213> Homo sapien

<400> 741
 ctgaggccca cgcagggcct agggtgggaa gatggcaggt gggggcggcg 50

 acctgagcac caggaggctg aatgaatgta tttcaccagt agcaaatgag 100

 atgaaccatc ttcctgcaca cagccacgat ttgcaaagga tgttcacgga 150

 agaccagggt gtagatgaca ggctgctcta tgacattgta ttcaagcact 200

 tcaaaagaaa taaggtggag atttcaaatg caataaaaaa gacatttcca 250

 ttcctcgagg gcctccgtga tcgtgatctc atcacaaata aaatgtttga 300

 agattctcaa gattcttgta gaaacctggt ccctgtacag agagtggtgt 350

 acaatgttct tagtgaactg gagaagacat ttaacctgcc agttctggaa 400

 gcactgttca gcgatgtcaa catgcaggaa taccccgatt taattcacat 450

 ttataaaggc tttgaaaatg taatccatga caaattgcct ctccaagaaa 500

 gtgaagaaga agagagggag gagaggtctg gcctccaact aagtcttgaa 550

 caaggaactg gtgaaaactc ttttcgaagc ctgacttggc caccttcggg 600

 ttccccatct catgctggta caaccccacc tgaaaatgga ctctcagagc 650

 acccctgtga aacagaacag ataaatgcaa agagaaaaga tacaaccagt 700

 gacaaagatg attcgctagg aagccaacaa acaaatgaac aatgtgctca 750

 aaaggctgag ccaacagagt cctgcgaaca aattgctgtc caagtgaata 800

 atggggatgc tggaagggag atgccctgcc cgttgccctg tgatgaagaa 850

 agcccagagg cagagctaca caaccatgga atccaaatta attcctgttc 900

 tgtgcgactg gtggatataa aaaaggaaaa gccattttct aattcaaaag 950

 ttgagtgcca agcccaagca agaactcatc ataaccaggc atctgacata 1000

 atagtcatca gcagtgagga ctctgaagga tccactgacg ttgatgagcc 1050

 cttagaagtc ttcatctcag caccgagaag tgagcctgtg atcaataatg 1100

 acaacccttt agaatcaaat gatgaaaagg agggccaaga agccacttgc 1150

 tcacgacccc agattgtacc agagcccatg gatttcagaa aattatctac 1200

 attcagagaa agttttaaga aaagagtgat aggacaagac cacgactttt 1250

 cagaatccag tgaggaggag gcgcccgcag aagcctcaag cggggcactg 1300

 agaagcaagc atggtgagaa ggctcctatg acttctagaa gtacatctac 1350

 ttggagaata cccagcagga agagacgttt cagcagtagt gacttttcag 1400

 acctgagtaa tggagaagag cttcaggaaa cctgcagctc atccctaaga 1450

 agagggtcag gatcacagcc acaagaacct gaaaataaga agtgctcctg 1500

 tgtcatgtgt tttccaaaag gtgtgccaag aagccaagaa gcaaggactg 1550

 aaagtagtca agcatctgac atgatggata ccatggatgt tgaaaacaat 1600

 tctactttgg aaaaacacag tgggaaaaga agaaaaaaga gaaggcatag 1650

 atctaaagta aatggtctcc aaagagggag aaagaaagac agacctagaa 1700

 aacatttaac tctgaataac aaagtccaaa agaaaagatg gcaacaaaga 1750

 ggaagaaaag ccaacactag acctttgaaa agaagaagaa aaagaggtcc 1800

 aagaattccc aaagatgaaa atattaattt taaacaatct gaacttcctg 1850

 tgacctgtgg tgaggtgaag ggcactctat ataaggagcg attcaaacaa 1900

 ggaacctcaa agaagtgtat acagagtgag gataaaaagt ggttcactcc 1950

 cagggaattt gaaattgaag gagaccgcgg agcatccaag aactggaagc 2000

 taagtatacg ctgcggtgga tataccctga aagtcctgat ggagaacaaa 2050

 tttctgccag aaccaccaag cacaagaaaa aagagaatac tggaatctca 2100

 caacaatacc ttagttgacc cttgtgagga gcataagaag aagaacccag 2150

 atgcttcagt caagttctca gagtttttaa agaagtgctc agagacatgg 2200

 aagaccattt ttgctaaaga gaaaggaaaa tttgaagata tggcaaaggc 2250

 ggacaaggcc cattatgaaa gagaaatgaa aacctatatc cctcctaaag 2300

 gggagaaaaa aaagaagttc aaggatccca atgcacccaa gaggcctcct 2350

 ttggcctttt tcctgttctg ctctgagtat cgcccaaaaa tcaaaggaga 2400

 acatcctggc ctgtccattg atgatgttgt gaagaaactg gcagggatgt 2450

 ggaataacac cgctgcagct gacaagcagt tttatgaaaa gaaggctgca 2500

 aagctgaagg aaaaatacaa aaaggatatt gctgcatatc gagctaaagg 2550

 aaagcctaat tcagcaaaaa agagagttgt caaggctgaa aaaagcaaga 2600

 aaaagaagga agaggaagaa gatgaagagg atgaacaaga ggaggaaaat 2650

 gaagaagatg atgataaata agttgcttct agtgcagttt ttttcttgtc 2700

 tataaagcat ttaagctgcc tgtacacaac tcactccttt taaagaaaaa 2750

 aacttcaacg taagactgtg taagatttgt ttttaaaccg tacactgtgt 2800

 ttttttgtat agttaaccac taccgaatgt gtcttcagat agccctgtcc 2850

 tggtggtatt tagccactaa cctttgcctg gtacagtatg ggggttgtaa 2900

 attggcatgg aaatttaaag caggttcttg ttagtgcaca gcacaaatta 2950

 gttgtatagg aggatggtag ttttttcacc ttcagttgtc tctgatgtag 3000

 cttatacaaa acatttgttg ttctgttaac tgaatgccac tctgtaattg 3050

 caaaaaaaaa aaacagttgc agctgttttg ttgacattct gaatgcttct 3100

 aagtaaatac aatttttaaa aaaccgtatg agggaactgt gtagacaagg 3150

 taccaggtca gtcttcttcc atgttctatt agctccacaa agccaatctc 3200

 aatccctcaa aacaatcttg tcatacttga aaatatgaca ctctagtcaa 3250

 agccttggta aaataatcag tgtttccaat ctgtcctgtt acaaaagaaa 3300

 cagattatta ttgaacttat gcaaataacc attgtcataa gaatgtttat 3350

 gaatagtttc caaattatgg caaattcatg tagagagaga aaagtaactg 3400

 ttttggtttt gctcacaaaa gtctacttta cctaagggct gtcagatata 3450

 agtaacttaa aagaaagaga agttttcttg acttttgaaa acaaaatatg 3500

 aaaagaatcg gcaatgtttc aaacaaaaag tcataaaagt cactttattc 3550

 ctccatcaaa aaaaaaaaaa aaaaaaaaa 3579

<210> 742
<211> 879
<212> PRT
<213> Homo sapien

<400> 742
 Met Ala Gly Gly Gly Gly Asp Leu Ser Thr Arg Arg Leu Asn Glu
   1               5                  10                  15

 Cys Ile Ser Pro Val Ala Asn Glu Met Asn His Leu Pro Ala His
                  20                  25                  30

 Ser His Asp Leu Gln Arg Met Phe Thr Glu Asp Gln Gly Val Asp
                  35                  40                  45

 Asp Arg Leu Leu Tyr Asp Ile Val Phe Lys His Phe Lys Arg Asn
                  50                  55                  60

 Lys Val Glu Ile Ser Asn Ala Ile Lys Lys Thr Phe Pro Phe Leu
                  65                  70                  75

 Glu Gly Leu Arg Asp Arg Asp Leu Ile Thr Asn Lys Met Phe Glu
                  80                  85                  90

 Asp Ser Gln Asp Ser Cys Arg Asn Leu Val Pro Val Gln Arg Val
                  95                 100                 105

 Val Tyr Asn Val Leu Ser Glu Leu Glu Lys Thr Phe Asn Leu Pro
                 110                 115                 120

 Val Leu Glu Ala Leu Phe Ser Asp Val Asn Met Gln Glu Tyr Pro
                 125                 130                 135

 Asp Leu Ile His Ile Tyr Lys Gly Phe Glu Asn Val Ile His Asp
                 140                 145                 150

 Lys Leu Pro Leu Gln Glu Ser Glu Glu Glu Glu Arg Glu Glu Arg
                 155                 160                 165

 Ser Gly Leu Gln Leu Ser Leu Glu Gln Gly Thr Gly Glu Asn Ser
                 170                 175                 180

 Phe Arg Ser Leu Thr Trp Pro Pro Ser Gly Ser Pro Ser His Ala
                 185                 190                 195

 Gly Thr Thr Pro Pro Glu Asn Gly Leu Ser Glu His Pro Cys Glu
                 200                 205                 210

 Thr Glu Gln Ile Asn Ala Lys Arg Lys Asp Thr Thr Ser Asp Lys
                 215                 220                 225

 Asp Asp Ser Leu Gly Ser Gln Gln Thr Asn Glu Gln Cys Ala Gln
                 230                 235                 240

 Lys Ala Glu Pro Thr Glu Ser Cys Glu Gln Ile Ala Val Gln Val
                 245                 250                 255

 Asn Asn Gly Asp Ala Gly Arg Glu Met Pro Cys Pro Leu Pro Cys
                 260                 265                 270

 Asp Glu Glu Ser Pro Glu Ala Glu Leu His Asn His Gly Ile Gln
                 275                 280                 285

 Ile Asn Ser Cys Ser Val Arg Leu Val Asp Ile Lys Lys Glu Lys
                 290                 295                 300

 Pro Phe Ser Asn Ser Lys Val Glu Cys Gln Ala Gln Ala Arg Thr
                 305                 310                 315

 His His Asn Gln Ala Ser Asp Ile Ile Val Ile Ser Ser Glu Asp
                 320                 325                 330

 Ser Glu Gly Ser Thr Asp Val Asp Glu Pro Leu Glu Val Phe Ile
                 335                 340                 345

 Ser Ala Pro Arg Ser Glu Pro Val Ile Asn Asn Asp Asn Pro Leu
                 350                 355                 360

 Glu Ser Asn Asp Glu Lys Glu Gly Gln Glu Ala Thr Cys Ser Arg
                 365                 370                 375

 Pro Gln Ile Val Pro Glu Pro Met Asp Phe Arg Lys Leu Ser Thr
                 380                 385                 390

 Phe Arg Glu Ser Phe Lys Lys Arg Val Ile Gly Gln Asp His Asp
                 395                 400                 405

 Phe Ser Glu Ser Ser Glu Glu Glu Ala Pro Ala Glu Ala Ser Ser
                 410                 415                 420

 Gly Ala Leu Arg Ser Lys His Gly Glu Lys Ala Pro Met Thr Ser
                 425                 430                 435

 Arg Ser Thr Ser Thr Trp Arg Ile Pro Ser Arg Lys Arg Arg Phe
                 440                 445                 450

 Ser Ser Ser Asp Phe Ser Asp Leu Ser Asn Gly Glu Glu Leu Gln
                 455                 460                 465

 Glu Thr Cys Ser Ser Ser Leu Arg Arg Gly Ser Gly Ser Gln Pro
                 470                 475                 480

 Gln Glu Pro Glu Asn Lys Lys Cys Ser Cys Val Met Cys Phe Pro
                 485                 490                 495

 Lys Gly Val Pro Arg Ser Gln Glu Ala Arg Thr Glu Ser Ser Gln
                 500                 505                 510

 Ala Ser Asp Met Met Asp Thr Met Asp Val Glu Asn Asn Ser Thr
                 515                 520                 525

 Leu Glu Lys His Ser Gly Lys Arg Arg Lys Lys Arg Arg His Arg
                 530                 535                 540

 Ser Lys Val Asn Gly Leu Gln Arg Gly Arg Lys Lys Asp Arg Pro
                 545                 550                 555

 Arg Lys His Leu Thr Leu Asn Asn Lys Val Gln Lys Lys Arg Trp
                 560                 565                 570

 Gln Gln Arg Gly Arg Lys Ala Asn Thr Arg Pro Leu Lys Arg Arg
                 575                 580                 585

 Arg Lys Arg Gly Pro Arg Ile Pro Lys Asp Glu Asn Ile Asn Phe
                 590                 595                 600

 Lys Gln Ser Glu Leu Pro Val Thr Cys Gly Glu Val Lys Gly Thr
                 605                 610                 615

 Leu Tyr Lys Glu Arg Phe Lys Gln Gly Thr Ser Lys Lys Cys Ile
                 620                 625                 630

 Gln Ser Glu Asp Lys Lys Trp Phe Thr Pro Arg Glu Phe Glu Ile
                 635                 640                 645

 Glu Gly Asp Arg Gly Ala Ser Lys Asn Trp Lys Leu Ser Ile Arg
                 650                 655                 660

 Cys Gly Gly Tyr Thr Leu Lys Val Leu Met Glu Asn Lys Phe Leu
                 665                 670                 675

 Pro Glu Pro Pro Ser Thr Arg Lys Lys Arg Ile Leu Glu Ser His
                 680                 685                 690

 Asn Asn Thr Leu Val Asp Pro Cys Glu Glu His Lys Lys Lys Asn
                 695                 700                 705

 Pro Asp Ala Ser Val Lys Phe Ser Glu Phe Leu Lys Lys Cys Ser
                 710                 715                 720

 Glu Thr Trp Lys Thr Ile Phe Ala Lys Glu Lys Gly Lys Phe Glu
                 725                 730                 735

 Asp Met Ala Lys Ala Asp Lys Ala His Tyr Glu Arg Glu Met Lys
                 740                 745                 750

 Thr Tyr Ile Pro Pro Lys Gly Glu Lys Lys Lys Lys Phe Lys Asp
                 755                 760                 765

 Pro Asn Ala Pro Lys Arg Pro Pro Leu Ala Phe Phe Leu Phe Cys
                 770                 775                 780

 Ser Glu Tyr Arg Pro Lys Ile Lys Gly Glu His Pro Gly Leu Ser
                 785                 790                 795

 Ile Asp Asp Val Val Lys Lys Leu Ala Gly Met Trp Asn Asn Thr
                 800                 805                 810

 Ala Ala Ala Asp Lys Gln Phe Tyr Glu Lys Lys Ala Ala Lys Leu
                 815                 820                 825

 Lys Glu Lys Tyr Lys Lys Asp Ile Ala Ala Tyr Arg Ala Lys Gly
                 830                 835                 840

 Lys Pro Asn Ser Ala Lys Lys Arg Val Val Lys Ala Glu Lys Ser
                 845                 850                 855

 Lys Lys Lys Lys Glu Glu Glu Glu Asp Glu Glu Asp Glu Gln Glu
                 860                 865                 870

 Glu Glu Asn Glu Glu Asp Asp Asp Lys
                 875

<210> 743
<211> 1590
<212> DNA
<213> Homo sapien

<400> 743
 gaggcagttc tgttgccact ctctctcctg tcaatgatgg atctcagaaa 50

 taccccagcc aaatctctgg acaagttcat tgaagactat ctcttgccag 100

 acacgtgttt ccgcatgcaa atcgaccatg ccattgacat catctgtggg 150

 ttcctgaagg aaaggtgctt ccgaggtagc tcctaccctg tgtgtgtgtc 200

 caaggtggta aagggtggct cctcaggcaa gggcaccacc ctcagaggcc 250

 gatctgacgc tgacctggtt gtcttcctca gtcctctcac cacttttcag 300

 gatcagttaa atcgccgggg agagttcatc caggaaatta ggagacagct 350

 ggaagcctgt caaagagaga gagcactttc cgtgaagttt gaggtccagg 400

 ctccacgctg gggcaacccc cgtgcgctca gcttcgtact gagttcgctc 450

 cagctcgggg agggggtgga gttcgatgtg ctgcctgcct ttgatgccct 500

 gggtcagttg actggcagct ataaacctaa cccccaaatc tatgtcaagc 550

 tcatcgagga gtgcaccgac ctgcagaaag agggcgagtt ctccacctgc 600

 ttcacagaac tacagagaga cttcctgaag cagcgcccca ccaagctcaa 650

 gagcctcatc cgcctagtca agcactggta ccaaaattgt aagaagaagc 700

 ttgggaagct gccacctcag tatgccctgg agctcctgac ggtctatgct 750

 tgggagcgag ggagcatgaa aacacatttc aacacagccc aaggatttcg 800

 gacggtcttg gaattagtca taaactacca gcaactctgc atctactgga 850

 caaagtatta tgactttaaa aaccccatta ttgaaaagta cctgagaagg 900

 cagctcacga aacccaggcc tgtgatcctg gacccggcgg accctacagg 950

 aaacttgggt ggtggagacc caaagggttg gaggcagctg gcacaagagg 1000

 ctgaggcctg gctgaattac ccatgcttta agaattggga tgggtcccca 1050

 gtgagctcct ggattctgct ggctgaaagc aacagtacag acgatgagac 1100

 cgacgatccc aggacgtatc agaaatatgg ttacattgga acacatgagt 1150

 accctcattt ctctcataga cccagcacgc tccaggcagc atccacccca 1200

 caggcagaag aggactggac ctgcaccatc ctctgaatgc cagtgcatct 1250

 tgggggaaag ggctccagtg ttatctggac cagttccttc attttcaggt 1300

 gggactcttg atccagagaa gacaaagctc ctcagtgagc tggtgtataa 1350

 tccaagacag aacccaagtc tcctgactcc tggccttcta tgccctctat 1400

 cctatcatag ataacattct ccacagcctc acttcattcc acctattctc 1450

 tgaaaatatt ccctgagaga gaacagagag atttagataa gagaatgaaa 1500

 ttccagcctt gactttcttc tgtgcacctg atgggagggt aatgtctaat 1550

 gtattatcaa taacaataaa aataaagcaa ataccaaaaa 1590

<210> 744
<211> 400
<212> PRT
<213> Homo sapien

<400> 744
 Met Met Asp Leu Arg Asn Thr Pro Ala Lys Ser Leu Asp Lys Phe
   1               5                  10                  15

 Ile Glu Asp Tyr Leu Leu Pro Asp Thr Cys Phe Arg Met Gln Ile
                  20                  25                  30

 Asp His Ala Ile Asp Ile Ile Cys Gly Phe Leu Lys Glu Arg Cys
                  35                  40                  45

 Phe Arg Gly Ser Ser Tyr Pro Val Cys Val Ser Lys Val Val Lys
                  50                  55                  60

 Gly Gly Ser Ser Gly Lys Gly Thr Thr Leu Arg Gly Arg Ser Asp
                  65                  70                  75

 Ala Asp Leu Val Val Phe Leu Ser Pro Leu Thr Thr Phe Gln Asp
                  80                  85                  90

 Gln Leu Asn Arg Arg Gly Glu Phe Ile Gln Glu Ile Arg Arg Gln
                  95                 100                 105

 Leu Glu Ala Cys Gln Arg Glu Arg Ala Leu Ser Val Lys Phe Glu
                 110                 115                 120

 Val Gln Ala Pro Arg Trp Gly Asn Pro Arg Ala Leu Ser Phe Val
                 125                 130                 135

 Leu Ser Ser Leu Gln Leu Gly Glu Gly Val Glu Phe Asp Val Leu
                 140                 145                 150

 Pro Ala Phe Asp Ala Leu Gly Gln Leu Thr Gly Ser Tyr Lys Pro
                 155                 160                 165

 Asn Pro Gln Ile Tyr Val Lys Leu Ile Glu Glu Cys Thr Asp Leu
                 170                 175                 180

 Gln Lys Glu Gly Glu Phe Ser Thr Cys Phe Thr Glu Leu Gln Arg
                 185                 190                 195

 Asp Phe Leu Lys Gln Arg Pro Thr Lys Leu Lys Ser Leu Ile Arg
                 200                 205                 210

 Leu Val Lys His Trp Tyr Gln Asn Cys Lys Lys Lys Leu Gly Lys
                 215                 220                 225

 Leu Pro Pro Gln Tyr Ala Leu Glu Leu Leu Thr Val Tyr Ala Trp
                 230                 235                 240

 Glu Arg Gly Ser Met Lys Thr His Phe Asn Thr Ala Gln Gly Phe
                 245                 250                 255

 Arg Thr Val Leu Glu Leu Val Ile Asn Tyr Gln Gln Leu Cys Ile
                 260                 265                 270

 Tyr Trp Thr Lys Tyr Tyr Asp Phe Lys Asn Pro Ile Ile Glu Lys
                 275                 280                 285

 Tyr Leu Arg Arg Gln Leu Thr Lys Pro Arg Pro Val Ile Leu Asp
                 290                 295                 300

 Pro Ala Asp Pro Thr Gly Asn Leu Gly Gly Gly Asp Pro Lys Gly
                 305                 310                 315

 Trp Arg Gln Leu Ala Gln Glu Ala Glu Ala Trp Leu Asn Tyr Pro
                 320                 325                 330

 Cys Phe Lys Asn Trp Asp Gly Ser Pro Val Ser Ser Trp Ile Leu
                 335                 340                 345

 Leu Ala Glu Ser Asn Ser Thr Asp Asp Glu Thr Asp Asp Pro Arg
                 350                 355                 360

 Thr Tyr Gln Lys Tyr Gly Tyr Ile Gly Thr His Glu Tyr Pro His
                 365                 370                 375

 Phe Ser His Arg Pro Ser Thr Leu Gln Ala Ala Ser Thr Pro Gln
                 380                 385                 390

 Ala Glu Glu Asp Trp Thr Cys Thr Ile Leu
                 395                 400

<210> 745
<211> 1686
<212> DNA
<213> Homo sapien

<400> 745
 ccacgcgtcc gggcgtaagc caggcgtgtt aaagccggtc ggaactgctc 50

 cggagggcac gggctccgta ggcaccaact gcaaggaccc ctccccctgc 100

 gggcgctccc atggcacagt tcgcgttcga gagtgacctg cactcgctgc 150

 ttcagctgga tgcacccatc cccaatgcac cccctgcgcg ctggcagcgc 200

 aaagccaagg aagccgcagg cccggccccc tcacccatgc gggccgccaa 250

 ccgatcccac agcgccggca ggactccggg ccgaactcct ggcaaatcca 300

 gttccaaggt tcagaccact cctagcaaac ctggcggtga ccgctatatc 350

 ccccatcgca gtgctgccca gatggaggtg gccagcttcc tcctgagcaa 400

 ggagaaccag tctgaaaaca gccagacgcc caccaagaag gaacatcaga 450

 aagcctgggc tttgaacctg aacggttttg atgtagagga agccaagatc 500

 cttcggctca gtggaaaacc acaaaatgcg ccagagggtt atcagaacag 550

 actgaaagta ctctacagcc aaaaggccac tcctggctcc agccggaaga 600

 cctgccgtta cattccttcc ctgccagacc gtatcctgga tgcgcctgaa 650

 atccgaaatg actattacct gaaccttgtg gattggagtt ctgggaatgt 700

 actggccgtg gcactggaca acagtgtgta cctgtggagt gcaagctctg 750

 gtgacatcct gcagcttttg caaatggagc agcctgggga atatatatcc 800

 tctgtggcct ggatcaaaga gggcaactac ttggctgtgg gcaccagcag 850

 tgctgaggtg cagctatggg atgtgcagca gcagaaacgg cttcgaaata 900

 tgaccagtca ctctgcccga gtgggctccc taagctggaa cagctatatc 950

 ctgtccagtg gttcacgttc tggccacatc caccaccatg atgttcgggt 1000

 agcagaacac catgtggcca cactgagtgg ccacagccag gaagtgtgtg 1050

 ggctgcgctg ggccccagat ggacgacatt tggccagtgg tggtaatgat 1100

 aacttggtca atgtgtggcc tagtgctcct ggagagggtg gctgggttcc 1150

 tctgcagaca ttcacccagc atcaaggggc tgtcaaggcc gtagcatggt 1200

 gtccctggca gtccaatgtc ctggcaacag gagggggcac cagtgatcga 1250

 cacattcgca tctggaatgt gtgctctggg gcctgtctga gtgccgtgga 1300

 tgcccattcc caggtgtgct ccatcctctg gtctccccat tacaaggagc 1350

 tcatctcagg ccatggcttt gcacagaacc agctagttat ttggaagtac 1400

 ccaaccatgg ccaaggtggc tgaactcaaa ggtcacacat cccgggtcct 1450

 gagtctgacc atgagcccag atggggccac agtggcatcc gcagcagcag 1500

 atgagaccct gaggctatgg cgctgttttg agttggaccc tgcgcggcgg 1550

 cgggagcggg agaaggccag tgcagccaaa agcagcctca tccaccaagg 1600

 catccgctga agaccaaccc atcacctcag ttgtttttta tttttctaat 1650

 aaagtcatgt ctcccttcat gttttttttt ttaaaa 1686

<210> 746
<211> 499
<212> PRT
<213> Homo sapien

<400> 746
 Met Ala Gln Phe Ala Phe Glu Ser Asp Leu His Ser Leu Leu Gln
   1               5                  10                  15

 Leu Asp Ala Pro Ile Pro Asn Ala Pro Pro Ala Arg Trp Gln Arg
                  20                  25                  30

 Lys Ala Lys Glu Ala Ala Gly Pro Ala Pro Ser Pro Met Arg Ala
                  35                  40                  45

 Ala Asn Arg Ser His Ser Ala Gly Arg Thr Pro Gly Arg Thr Pro
                  50                  55                  60

 Gly Lys Ser Ser Ser Lys Val Gln Thr Thr Pro Ser Lys Pro Gly
                  65                  70                  75

 Gly Asp Arg Tyr Ile Pro His Arg Ser Ala Ala Gln Met Glu Val
                  80                  85                  90

 Ala Ser Phe Leu Leu Ser Lys Glu Asn Gln Ser Glu Asn Ser Gln
                  95                 100                 105

 Thr Pro Thr Lys Lys Glu His Gln Lys Ala Trp Ala Leu Asn Leu
                 110                 115                 120

 Asn Gly Phe Asp Val Glu Glu Ala Lys Ile Leu Arg Leu Ser Gly
                 125                 130                 135

 Lys Pro Gln Asn Ala Pro Glu Gly Tyr Gln Asn Arg Leu Lys Val
                 140                 145                 150

 Leu Tyr Ser Gln Lys Ala Thr Pro Gly Ser Ser Arg Lys Thr Cys
                 155                 160                 165

 Arg Tyr Ile Pro Ser Leu Pro Asp Arg Ile Leu Asp Ala Pro Glu
                 170                 175                 180

 Ile Arg Asn Asp Tyr Tyr Leu Asn Leu Val Asp Trp Ser Ser Gly
                 185                 190                 195

 Asn Val Leu Ala Val Ala Leu Asp Asn Ser Val Tyr Leu Trp Ser
                 200                 205                 210

 Ala Ser Ser Gly Asp Ile Leu Gln Leu Leu Gln Met Glu Gln Pro
                 215                 220                 225

 Gly Glu Tyr Ile Ser Ser Val Ala Trp Ile Lys Glu Gly Asn Tyr
                 230                 235                 240

 Leu Ala Val Gly Thr Ser Ser Ala Glu Val Gln Leu Trp Asp Val
                 245                 250                 255

 Gln Gln Gln Lys Arg Leu Arg Asn Met Thr Ser His Ser Ala Arg
                 260                 265                 270

 Val Gly Ser Leu Ser Trp Asn Ser Tyr Ile Leu Ser Ser Gly Ser
                 275                 280                 285

 Arg Ser Gly His Ile His His His Asp Val Arg Val Ala Glu His
                 290                 295                 300

 His Val Ala Thr Leu Ser Gly His Ser Gln Glu Val Cys Gly Leu
                 305                 310                 315

 Arg Trp Ala Pro Asp Gly Arg His Leu Ala Ser Gly Gly Asn Asp
                 320                 325                 330

 Asn Leu Val Asn Val Trp Pro Ser Ala Pro Gly Glu Gly Gly Trp
                 335                 340                 345

 Val Pro Leu Gln Thr Phe Thr Gln His Gln Gly Ala Val Lys Ala
                 350                 355                 360

 Val Ala Trp Cys Pro Trp Gln Ser Asn Val Leu Ala Thr Gly Gly
                 365                 370                 375

 Gly Thr Ser Asp Arg His Ile Arg Ile Trp Asn Val Cys Ser Gly
                 380                 385                 390

 Ala Cys Leu Ser Ala Val Asp Ala His Ser Gln Val Cys Ser Ile
                 395                 400                 405

 Leu Trp Ser Pro His Tyr Lys Glu Leu Ile Ser Gly His Gly Phe
                 410                 415                 420

 Ala Gln Asn Gln Leu Val Ile Trp Lys Tyr Pro Thr Met Ala Lys
                 425                 430                 435

 Val Ala Glu Leu Lys Gly His Thr Ser Arg Val Leu Ser Leu Thr
                 440                 445                 450

 Met Ser Pro Asp Gly Ala Thr Val Ala Ser Ala Ala Ala Asp Glu
                 455                 460                 465

 Thr Leu Arg Leu Trp Arg Cys Phe Glu Leu Asp Pro Ala Arg Arg
                 470                 475                 480

 Arg Glu Arg Glu Lys Ala Ser Ala Ala Lys Ser Ser Leu Ile His
                 485                 490                 495

 Gln Gly Ile Arg


<210> 747
<211> 1760
<212> DNA
<213> Homo sapien

<400> 747
 gcagcaggcc aagggggagg tgcgagcgtg gacctgggac gggtctgggc 50

 ggctctcggt ggttggcacg ggttcgcaca cccattcaag cggcaggacg 100

 cacttgtctt agcagttctc gctgaccgcg ctagctgcgg cttctacgct 150

 ccggcactct gagttcatca gcaaacgccc tggcgtctgt cctcaccatg 200

 cctagccttt gggaccgctt ctcgtcgtcg tccacctcct cttcgccctc 250

 gtccttgccc cgaactccca ccccagatcg gccgccgcgc tcagcctggg 300

 ggtcggcgac ccgggaggag gggtttgacc gctccacgag cctggagagc 350

 tcggactgcg agtccctgga cagcagcaac agtggcttcg ggccggagga 400

 agacacggct tacctggatg gggtgtcgtt gcccgacttc gagctgctca 450

 gtgaccctga ggatgaacac ttgtgtgcca acctgatgca gctgctgcag 500

 gagagcctgg cccaggcgcg gctgggctct cgacgccctg cgcgcctgct 550

 gatgcctagc cagttggtaa gccaggtggg caaagaacta ctgcgcctgg 600

 cctacagcga gccgtgcggc ctgcgggggg cgctgctgga cgtctgcgtg 650

 gagcagggca agagctgcca cagcgtgggc cagctggcac tcgaccccag 700

 cctggtgccc accttccagc tgaccctcgt gctgcgcctg gactcacgac 750

 tctggcccaa gatccagggg ctgtttagct ccgccaactc tcccttcctc 800

 cctggcttca gccagtccct gacgctgagc actggcttcc gagtcatcaa 850

 gaagaagctg tacagctcgg aacagctgct cattgaggag tgttgaactt 900

 caacctgagg gggccgacag tgccctccaa gacagagacg actgaacttt 950

 tggggtggag actagaggca ggagctgagg gactgattcc agtggttgga 1000

 aaactgaggc agccacctaa ggtggaggtg ggggaatagt gtttcccagg 1050

 aagctcattg agttgtgtgc gggtggctgt gcattgggga cacatacccc 1100

 tcagtactgt agcatggaac aaaggcttag gggccaacaa ggcttccagc 1150

 tggatgtgtg tgtagcatgt accttattat ttttgttact gacagttaac 1200

 agtggtgtga catccagaga gcagctgggc tgctcccgcc ccagcctggc 1250

 ccagggtgaa ggaagaggca cgtgctcctc agagcagccg gagggagggg 1300

 ggaggtcgga ggtcgtggag gtggtttgtg tatcttactg gtctgaaggg 1350

 accaagtgtg tttgttgttt gttttgtatc ttgtttttct gatcggagca 1400

 tcactactga cctgttgtag gcagctatct tacagacgca tgaatgtaag 1450

 agtaggaagg ggtgggtgtc agggatcact tgggatcttt gacacttgaa 1500

 aaattacacc tggcagctgc gtttaagcct tcccccatcg tgtactgcag 1550

 agttgagctg gcaggggagg ggctgagagg gtgggggctg gaacccctcc 1600

 ccgggaggag tgccatctgg gtcttccatc tagaactgtt tacatgaaga 1650

 taagatactc actgttcatg aatacacttg atgttcaagt attaagacct 1700

 atgcaatatt ttttactttt ctaataaaca tgtttgttaa aacaaaaaaa 1750

 aaaaaaaaaa 1760

<210> 748
<211> 232
<212> PRT
<213> Homo sapien

<400> 748
 Met Pro Ser Leu Trp Asp Arg Phe Ser Ser Ser Ser Thr Ser Ser
   1               5                  10                  15

 Ser Pro Ser Ser Leu Pro Arg Thr Pro Thr Pro Asp Arg Pro Pro
                  20                  25                  30

 Arg Ser Ala Trp Gly Ser Ala Thr Arg Glu Glu Gly Phe Asp Arg
                  35                  40                  45

 Ser Thr Ser Leu Glu Ser Ser Asp Cys Glu Ser Leu Asp Ser Ser
                  50                  55                  60

 Asn Ser Gly Phe Gly Pro Glu Glu Asp Thr Ala Tyr Leu Asp Gly
                  65                  70                  75

 Val Ser Leu Pro Asp Phe Glu Leu Leu Ser Asp Pro Glu Asp Glu
                  80                  85                  90

 His Leu Cys Ala Asn Leu Met Gln Leu Leu Gln Glu Ser Leu Ala
                  95                 100                 105

 Gln Ala Arg Leu Gly Ser Arg Arg Pro Ala Arg Leu Leu Met Pro
                 110                 115                 120

 Ser Gln Leu Val Ser Gln Val Gly Lys Glu Leu Leu Arg Leu Ala
                 125                 130                 135

 Tyr Ser Glu Pro Cys Gly Leu Arg Gly Ala Leu Leu Asp Val Cys
                 140                 145                 150

 Val Glu Gln Gly Lys Ser Cys His Ser Val Gly Gln Leu Ala Leu
                 155                 160                 165

 Asp Pro Ser Leu Val Pro Thr Phe Gln Leu Thr Leu Val Leu Arg
                 170                 175                 180

 Leu Asp Ser Arg Leu Trp Pro Lys Ile Gln Gly Leu Phe Ser Ser
                 185                 190                 195

 Ala Asn Ser Pro Phe Leu Pro Gly Phe Ser Gln Ser Leu Thr Leu
                 200                 205                 210

 Ser Thr Gly Phe Arg Val Ile Lys Lys Lys Leu Tyr Ser Ser Glu
                 215                 220                 225

 Gln Leu Leu Ile Glu Glu Cys
                 230

<210> 749
<211> 4100
<212> DNA
<213> Homo sapien

<400> 749
 gtacctcatg tgacaagttc caatttcttt tcaagtcaat tgaactgaaa 50

 tctccttgtt gctttgaaat cttagaagag agcccactaa ttcaaggact 100

 cttactgtgg gagcaactgc tggttctatc acaatgaaac ggctggtttg 150

 tgtgctcttg gtgtgctcct ctgcagtggc acagttgcat aaagatccta 200

 ccctggatca ccactggcat ctctggaaga aaacctatgg caaacaatac 250

 aaggaaaaga atgaagaagc agtacgacgt ctcatctggg aaaagaatct 300

 aaagtttgtg atgcttcaca acctggagca ttcaatggga atgcactcat 350

 acgatctggg catgaaccac ctgggagaca tgaccagtga agaagtgatg 400

 tctttgatga gttccctgag agttcccagc cagtggcaga gaaatatcac 450

 atataagtca aaccctaatc ggatattgcc tgattctgtg gactggagag 500

 agaaagggtg tgttactgaa gtgaaatatc aaggttcttg tggtgcttgc 550

 tgggctttca gtgctgtggg ggccctggaa gcacagctga agctgaaaac 600

 aggaaagctg gtgtctctca gtgcccagaa cctggtggat tgctcaactg 650

 aaaaatatgg aaacaaaggc tgcaatggtg gcttcatgac aacggctttc 700

 cagtacatca ttgataacaa gggcatcgac tcagacgctt cctatcccta 750

 caaagccatg gatcagaaat gtcaatatga ctcaaaatat cgtgctgcca 800

 catgttcaaa gtacactgaa cttccttatg gcagagaaga tgtcctgaaa 850

 gaagctgtgg ccaataaagg cccagtgtct gttggtgtag atgcgcgtca 900

 tccttctttc ttcctctaca gaagtggtgt ctactatgaa ccatcctgta 950

 ctcagaatgt gaatcatggt gtacttgtgg ttggctatgg tgatcttaat 1000

 gggaaagaat actggcttgt gaaaaacagc tggggccaca actttggtga 1050

 agaaggatat attcggatgg caagaaataa aggaaatcat tgtgggattg 1100

 ctagctttcc ctcttaccca gaaatctaga ggatctctcc tttttataac 1150

 aaatcaagaa atatgaagca ctttctctta acttaatttt tcctgctgta 1200

 tccagaagaa ataattgtgt catgattaat gtgtatttac tgtactaatt 1250

 agaaaatata gtttgaggcc gggcacggtg gctcacgcct gtaatcccag 1300

 tacttgggag gccaaggcag gcatatcaac ttgaggccag gagttaaaga 1350

 gcagcctggc taacatggtg aaaccccatc tctactaaaa atacaaaaaa 1400

 ttagccgagc acggtggtgc atgcctgtaa tcccagctac ttgggaggct 1450

 gaggcacgag attccttgaa cccaagaggt tgaggctatg ttgagctgag 1500

 atcacaccac tgtactccag cctggatgac agagtggaga ctctgtttca 1550

 aaaaaacaga aaagaaaata tagtttgatt cttcattttt ttaaatttgc 1600

 aaatctcagg ataaagtttg ctaagtaaat tagtaatgta ctatagatat 1650

 aactgtacaa aaattgttca acctaaaaca atctgtaatt gcttattgtt 1700

 ttattgtata ctctttgtct ttttaagacc cctaatagcc ttttgtaact 1750

 tgatggctta aaaatactta ataaatctgc catttcaaat ttctatcatt 1800

 gccacatacc attcttattc ctaggcaact attaataatc tatcctgaga 1850

 atattaattg tggtattctg gtgatggggt ttagcaactt tgatggaaga 1900

 aaatattagg ctataaatgt cctaaggact cagattgtat ctttgtacag 1950

 aagaggattc aaaacgccac gtgtagtggc tcatgcctgt aatcccaaca 2000

 ctttgggagg ctgaagtagg aggatcgtct tgagcccagg agttcaagac 2050

 cagcctggac aacatagtga gaccttgtct ccacaaaaat aaaaaagaaa 2100

 ctatccagga gtggtggtgt gtgcctgtgg tccctgctat gcagatgtct 2150

 aagacaggag gatcacaaga gcccaggagg ttgagaatgc agtgagcttg 2200

 taattgcacc actgcactcc agcctgggtg acagagcaag accctgtctt 2250

 aaaaaaagag gattcaacac atatttttat attatgttaa agtaaagaaa 2300

 tgcataaaag acaagcactt tggaagaatt attttaatga tcaacaattt 2350

 aatgtattag tccaaattat ttttacgtag tcatcaacaa tttgaccagg 2400

 gcctttattt ggcaaataac tgagccaacc agaataaaat aaccaatact 2450

 ccactgctca tatttttatc taattcagat ggatcttcct tacaactgct 2500

 ctagattagt agatgcatct aagcaggcag caggaacttt aaatttttta 2550

 agttcatgtc tatgacatga acaatgtgtg ggataatgtc attaatatat 2600

 cctaaattaa cctaaacgta tttcactaac tctggctcct tctccataaa 2650

 gcacatttta aggaacaaga attgctaaat ataaaaacat aaataatacc 2700

 ataatacatg gctatcatca aaagtgtata gaatattata gtttaaaagt 2750

 atttagttga ttacttttca gttttgtttt gttttttgag acggagtctc 2800

 actctgttgc ccaggctgga gtgcagtggc accatctcag ttcactgcaa 2850

 cttctgcctc ccgagttcaa gcgattctcc tgcctcagcc tcccgagtag 2900

 ctggaattat aggcgtgcac caccacgccc agctaatttt tgtattttta 2950

 gtaaagacag ggttttgcca cattagccag gctggtctca aactcctgac 3000

 ctcaggtgat ccacccaccc cagcctccca aagtgctaag attacaggcg 3050

 tgagccactg agcccagcct acttttcagt ttttaacata atttttgttt 3100

 tatccacaac ttttcaagta ttgaaagtag aataaaaaca tgggttctta 3150

 gtctttagct atctgttaaa gcctatgaat gccttcttaa aatcatgttt 3200

 ttaaatgcat aaaatatata ggattacaaa ggaatctaat tatatcgaaa 3250

 tacagttatt aaaatgttaa aagataagtt tgttatatat taatatgcat 3300

 gcttctttat aaatgcatta aataagagtt aatagctatc ctaaatttga 3350

 aatagtgata agcataatga aaatagatgc aaaaaactaa tgtgatatga 3400

 aaatatctgg gtttttcttt tgatgatgaa gtattgctaa tattaccgtg 3450

 gtttatgaac tatgttcaga attgaagaaa atcctaactt tcagttagag 3500

 gttagtgacg gggttcagga caccctacac aaaatacagc actttgacat 3550

 attgaatatt ttaagctgaa ggcatttgag gaaattgcag aagcaggaag 3600

 gtgactctga ccttctgcct gctgttctcc ccagaagcag ccataaaacc 3650

 tgggaaggat tttctgacct tcccctgaag tagatcataa gactgtcatg 3700

 taagaggtgc tctcctggca cccagagaaa aggagcatcc ttacctccaa 3750

 aagcacaggg acacaaagag gaatctaaac aaacaggcct ctcagtttcc 3800

 cccagtttat tacatttagc ttgttcacac tttgccctat gacatttcta 3850

 catcactggc tgctcttcat caaacctact ataaaaaaca ttcaagttca 3900

 actgtttctt tgggccttta tttccttatg gagcccctcg tgtcgtgtaa 3950

 aacttatatt aaataaatgt gcatgctttt ctcttgctaa tctctctttt 4000

 gttatagaga tctcagccct aaacctagga tggatagaag gaaacatatg 4050

 ttctccccta cattagtaaa aataaaaatg gaatttttta cccatacaaa 4100

<210> 750
<211> 331
<212> PRT
<213> Homo sapien

<400> 750
 Met Lys Arg Leu Val Cys Val Leu Leu Val Cys Ser Ser Ala Val
   1               5                  10                  15

 Ala Gln Leu His Lys Asp Pro Thr Leu Asp His His Trp His Leu
                  20                  25                  30

 Trp Lys Lys Thr Tyr Gly Lys Gln Tyr Lys Glu Lys Asn Glu Glu
                  35                  40                  45

 Ala Val Arg Arg Leu Ile Trp Glu Lys Asn Leu Lys Phe Val Met
                  50                  55                  60

 Leu His Asn Leu Glu His Ser Met Gly Met His Ser Tyr Asp Leu
                  65                  70                  75

 Gly Met Asn His Leu Gly Asp Met Thr Ser Glu Glu Val Met Ser
                  80                  85                  90

 Leu Met Ser Ser Leu Arg Val Pro Ser Gln Trp Gln Arg Asn Ile
                  95                 100                 105

 Thr Tyr Lys Ser Asn Pro Asn Arg Ile Leu Pro Asp Ser Val Asp
                 110                 115                 120

 Trp Arg Glu Lys Gly Cys Val Thr Glu Val Lys Tyr Gln Gly Ser
                 125                 130                 135

 Cys Gly Ala Cys Trp Ala Phe Ser Ala Val Gly Ala Leu Glu Ala
                 140                 145                 150

 Gln Leu Lys Leu Lys Thr Gly Lys Leu Val Ser Leu Ser Ala Gln
                 155                 160                 165

 Asn Leu Val Asp Cys Ser Thr Glu Lys Tyr Gly Asn Lys Gly Cys
                 170                 175                 180

 Asn Gly Gly Phe Met Thr Thr Ala Phe Gln Tyr Ile Ile Asp Asn
                 185                 190                 195

 Lys Gly Ile Asp Ser Asp Ala Ser Tyr Pro Tyr Lys Ala Met Asp
                 200                 205                 210

 Gln Lys Cys Gln Tyr Asp Ser Lys Tyr Arg Ala Ala Thr Cys Ser
                 215                 220                 225

 Lys Tyr Thr Glu Leu Pro Tyr Gly Arg Glu Asp Val Leu Lys Glu
                 230                 235                 240

 Ala Val Ala Asn Lys Gly Pro Val Ser Val Gly Val Asp Ala Arg
                 245                 250                 255

 His Pro Ser Phe Phe Leu Tyr Arg Ser Gly Val Tyr Tyr Glu Pro
                 260                 265                 270

 Ser Cys Thr Gln Asn Val Asn His Gly Val Leu Val Val Gly Tyr
                 275                 280                 285

 Gly Asp Leu Asn Gly Lys Glu Tyr Trp Leu Val Lys Asn Ser Trp
                 290                 295                 300

 Gly His Asn Phe Gly Glu Glu Gly Tyr Ile Arg Met Ala Arg Asn
                 305                 310                 315

 Lys Gly Asn His Cys Gly Ile Ala Ser Phe Pro Ser Tyr Pro Glu
                 320                 325                 330

 Ile


<210> 751
<211> 4100
<212> DNA
<213> Homo sapien

<400> 751
 gtacctcatg tgacaagttc caatttcttt tcaagtcaat tgaactgaaa 50

 tctccttgtt gctttgaaat cttagaagag agcccactaa ttcaaggact 100

 cttactgtgg gagcaactgc tggttctatc acaatgaaac ggctggtttg 150

 tgtgctcttg gtgtgctcct ctgcagtggc acagttgcat aaagatccta 200

 ccctggatca ccactggcat ctctggaaga aaacctatgg caaacaatac 250

 aaggaaaaga atgaagaagc agtacgacgt ctcatctggg aaaagaatct 300

 aaagtttgtg atgcttcaca acctggagca ttcaatggga atgcactcat 350

 acgatctggg catgaaccac ctgggagaca tgaccagtga agaagtgatg 400

 tctttgatga gttccctgag agttcccagc cagtggcaga gaaatatcac 450

 atataagtca aaccctaatc ggatattgcc tgattctgtg gactggagag 500

 agaaagggtg tgttactgaa gtgaaatatc aaggttcttg tggtgcttgc 550

 tgggctttca gtgctgtggg ggccctggaa gcacagctga agctgaaaac 600

 aggaaagctg gtgtctctca gtgcccagaa cctggtggat tgctcaactg 650

 aaaaatatgg aaacaaaggc tgcaatggtg gcttcatgac aacggctttc 700

 cagtacatca ttgataacaa gggcatcgac tcagacgctt cctatcccta 750

 caaagccatg gatcagaaat gtcaatatga ctcaaaatat cgtgctgcca 800

 catgttcaaa gtacactgaa cttccttatg gcagagaaga tgtcctgaaa 850

 gaagctgtgg ccaataaagg cccagtgtct gttggtgtag atgcgcgtca 900

 tccttctttc ttcctctaca gaagtggtgt ctactatgaa ccatcctgta 950

 ctcagaatgt gaatcatggt gtacttgtgg ttggctatgg tgatcttaat 1000

 gggaaagaat actggcttgt gaaaaacagc tggggccaca actttggtga 1050

 agaaggatat attcggatgg caagaaataa aggaaatcat tgtgggattg 1100

 ctagctttcc ctcttaccca gaaatctaga ggatctctcc tttttataac 1150

 aaatcaagaa atatgaagca ctttctctta acttaatttt tcctgctgta 1200

 tccagaagaa ataattgtgt catgattaat gtgtatttac tgtactaatt 1250

 agaaaatata gtttgaggcc gggcacggtg gctcacgcct gtaatcccag 1300

 tacttgggag gccaaggcag gcatatcaac ttgaggccag gagttaaaga 1350

 gcagcctggc taacatggtg aaaccccatc tctactaaaa atacaaaaaa 1400

 ttagccgagc acggtggtgc atgcctgtaa tcccagctac ttgggaggct 1450

 gaggcacgag attccttgaa cccaagaggt tgaggctatg ttgagctgag 1500

 atcacaccac tgtactccag cctggatgac agagtggaga ctctgtttca 1550

 aaaaaacaga aaagaaaata tagtttgatt cttcattttt ttaaatttgc 1600

 aaatctcagg ataaagtttg ctaagtaaat tagtaatgta ctatagatat 1650

 aactgtacaa aaattgttca acctaaaaca atctgtaatt gcttattgtt 1700

 ttattgtata ctctttgtct ttttaagacc cctaatagcc ttttgtaact 1750

 tgatggctta aaaatactta ataaatctgc catttcaaat ttctatcatt 1800

 gccacatacc attcttattc ctaggcaact attaataatc tatcctgaga 1850

 atattaattg tggtattctg gtgatggggt ttagcaactt tgatggaaga 1900

 aaatattagg ctataaatgt cctaaggact cagattgtat ctttgtacag 1950

 aagaggattc aaaacgccac gtgtagtggc tcatgcctgt aatcccaaca 2000

 ctttgggagg ctgaagtagg aggatcgtct tgagcccagg agttcaagac 2050

 cagcctggac aacatagtga gaccttgtct ccacaaaaat aaaaaagaaa 2100

 ctatccagga gtggtggtgt gtgcctgtgg tccctgctat gcagatgtct 2150

 aagacaggag gatcacaaga gcccaggagg ttgagaatgc agtgagcttg 2200

 taattgcacc actgcactcc agcctgggtg acagagcaag accctgtctt 2250

 aaaaaaagag gattcaacac atatttttat attatgttaa agtaaagaaa 2300

 tgcataaaag acaagcactt tggaagaatt attttaatga tcaacaattt 2350

 aatgtattag tccaaattat ttttacgtag tcatcaacaa tttgaccagg 2400

 gcctttattt ggcaaataac tgagccaacc agaataaaat aaccaatact 2450

 ccactgctca tatttttatc taattcagat ggatcttcct tacaactgct 2500

 ctagattagt agatgcatct aagcaggcag caggaacttt aaatttttta 2550

 agttcatgtc tatgacatga acaatgtgtg ggataatgtc attaatatat 2600

 cctaaattaa cctaaacgta tttcactaac tctggctcct tctccataaa 2650

 gcacatttta aggaacaaga attgctaaat ataaaaacat aaataatacc 2700

 ataatacatg gctatcatca aaagtgtata gaatattata gtttaaaagt 2750

 atttagttga ttacttttca gttttgtttt gttttttgag acggagtctc 2800

 actctgttgc ccaggctgga gtgcagtggc accatctcag ttcactgcaa 2850

 cttctgcctc ccgagttcaa gcgattctcc tgcctcagcc tcccgagtag 2900

 ctggaattat aggcgtgcac caccacgccc agctaatttt tgtattttta 2950

 gtaaagacag ggttttgcca cattagccag gctggtctca aactcctgac 3000

 ctcaggtgat ccacccaccc cagcctccca aagtgctaag attacaggcg 3050

 tgagccactg agcccagcct acttttcagt ttttaacata atttttgttt 3100

 tatccacaac ttttcaagta ttgaaagtag aataaaaaca tgggttctta 3150

 gtctttagct atctgttaaa gcctatgaat gccttcttaa aatcatgttt 3200

 ttaaatgcat aaaatatata ggattacaaa ggaatctaat tatatcgaaa 3250

 tacagttatt aaaatgttaa aagataagtt tgttatatat taatatgcat 3300

 gcttctttat aaatgcatta aataagagtt aatagctatc ctaaatttga 3350

 aatagtgata agcataatga aaatagatgc aaaaaactaa tgtgatatga 3400

 aaatatctgg gtttttcttt tgatgatgaa gtattgctaa tattaccgtg 3450

 gtttatgaac tatgttcaga attgaagaaa atcctaactt tcagttagag 3500

 gttagtgacg gggttcagga caccctacac aaaatacagc actttgacat 3550

 attgaatatt ttaagctgaa ggcatttgag gaaattgcag aagcaggaag 3600

 gtgactctga ccttctgcct gctgttctcc ccagaagcag ccataaaacc 3650

 tgggaaggat tttctgacct tcccctgaag tagatcataa gactgtcatg 3700

 taagaggtgc tctcctggca cccagagaaa aggagcatcc ttacctccaa 3750

 aagcacaggg acacaaagag gaatctaaac aaacaggcct ctcagtttcc 3800

 cccagtttat tacatttagc ttgttcacac tttgccctat gacatttcta 3850

 catcactggc tgctcttcat caaacctact ataaaaaaca ttcaagttca 3900

 actgtttctt tgggccttta tttccttatg gagcccctcg tgtcgtgtaa 3950

 aacttatatt aaataaatgt gcatgctttt ctcttgctaa tctctctttt 4000

 gttatagaga tctcagccct aaacctagga tggatagaag gaaacatatg 4050

 ttctccccta cattagtaaa aataaaaatg gaatttttta cccatacaaa 4100

<210> 752
<211> 331
<212> PRT
<213> Homo sapien

<400> 752
 Met Lys Arg Leu Val Cys Val Leu Leu Val Cys Ser Ser Ala Val
   1               5                  10                  15

 Ala Gln Leu His Lys Asp Pro Thr Leu Asp His His Trp His Leu
                  20                  25                  30

 Trp Lys Lys Thr Tyr Gly Lys Gln Tyr Lys Glu Lys Asn Glu Glu
                  35                  40                  45

 Ala Val Arg Arg Leu Ile Trp Glu Lys Asn Leu Lys Phe Val Met
                  50                  55                  60

 Leu His Asn Leu Glu His Ser Met Gly Met His Ser Tyr Asp Leu
                  65                  70                  75

 Gly Met Asn His Leu Gly Asp Met Thr Ser Glu Glu Val Met Ser
                  80                  85                  90

 Leu Met Ser Ser Leu Arg Val Pro Ser Gln Trp Gln Arg Asn Ile
                  95                 100                 105

 Thr Tyr Lys Ser Asn Pro Asn Arg Ile Leu Pro Asp Ser Val Asp
                 110                 115                 120

 Trp Arg Glu Lys Gly Cys Val Thr Glu Val Lys Tyr Gln Gly Ser
                 125                 130                 135

 Cys Gly Ala Cys Trp Ala Phe Ser Ala Val Gly Ala Leu Glu Ala
                 140                 145                 150

 Gln Leu Lys Leu Lys Thr Gly Lys Leu Val Ser Leu Ser Ala Gln
                 155                 160                 165

 Asn Leu Val Asp Cys Ser Thr Glu Lys Tyr Gly Asn Lys Gly Cys
                 170                 175                 180

 Asn Gly Gly Phe Met Thr Thr Ala Phe Gln Tyr Ile Ile Asp Asn
                 185                 190                 195

 Lys Gly Ile Asp Ser Asp Ala Ser Tyr Pro Tyr Lys Ala Met Asp
                 200                 205                 210

 Gln Lys Cys Gln Tyr Asp Ser Lys Tyr Arg Ala Ala Thr Cys Ser
                 215                 220                 225

 Lys Tyr Thr Glu Leu Pro Tyr Gly Arg Glu Asp Val Leu Lys Glu
                 230                 235                 240

 Ala Val Ala Asn Lys Gly Pro Val Ser Val Gly Val Asp Ala Arg
                 245                 250                 255

 His Pro Ser Phe Phe Leu Tyr Arg Ser Gly Val Tyr Tyr Glu Pro
                 260                 265                 270

 Ser Cys Thr Gln Asn Val Asn His Gly Val Leu Val Val Gly Tyr
                 275                 280                 285

 Gly Asp Leu Asn Gly Lys Glu Tyr Trp Leu Val Lys Asn Ser Trp
                 290                 295                 300

 Gly His Asn Phe Gly Glu Glu Gly Tyr Ile Arg Met Ala Arg Asn
                 305                 310                 315

 Lys Gly Asn His Cys Gly Ile Ala Ser Phe Pro Ser Tyr Pro Glu
                 320                 325                 330

 Ile


<210> 753
<211> 3178
<212> DNA
<213> Homo sapien

<400> 753
 agcctgtgga gacgggacag ccctgtccca ctcactcttt cccctgccgc 50

 tcctgccggc agctccaacc atgggaggcc gcgtctttct cgcattctgt 100

 gtctggctga ctctgccggg agctgaaacc caggactcca ggggctgtgc 150

 ccggtggtgc cctcagaact cctcgtgtgt caatgccacc gcctgtcgct 200

 gcaatccagg gttcagctct ttttctgaga tcatcaccac cccgacggag 250

 acttgtgacg acatcaacga gtgtgcaaca ccgtcgaaag tgtcatgcgg 300

 aaaattctcg gactgctgga acacagaggg gagctacgac tgcgtgtgca 350

 gcccgggata tgagcctgtt tctggggcaa aaacattcaa gaatgagagc 400

 gagaacacct gtcaagatgt ggacgaatgt cagcagaacc caaggctctg 450

 taaaagctac ggcacctgcg tcaacaccct tggcagctat acctgccagt 500

 gcctgcctgg cttcaagttc atacctgagg atccgaaggt ctgcacagat 550

 gtgaatgaat gcacctccgg acaaaacccg tgccacagct ccacccactg 600

 cctcaacaac gtgggcagct atcagtgccg ctgccgcccg ggctggcaac 650

 cgattccggg gtcccccaat ggcccaaaca ataccgtctg tgaagatgtg 700

 gacgagtgca gctccgggca gcatcagtgt gacagctcca ccgtctgctt 750

 caacaccgtg ggttcataca gctgccgctg ccgcccaggc tggaagccca 800

 gacacggaat cccgaataac caaaaggaca ctgtctgtga agatatgact 850

 ttctccacct ggaccccgcc ccctggagtc cacagccaga cgctttcccg 900

 attcttcgac aaagtccagg acctgggcag agactccaag acaagctcag 950

 ccgaggtcac catccagaat gtcatcaaat tggtggatga actgatggaa 1000

 gctcctggag acgtagaggc cctggcgcca cctgtccggc acctcatagc 1050

 cacccagctg ctctcaaacc ttgaagatat catgaggatc ctggccaaga 1100

 gcctgcctaa aggccccttc acctacattt ccccttcgaa cacagagctg 1150

 accctgatga tccaggagcg gggggacaag aacgtcacta tgggtcagag 1200

 cagcgcacgc atgaagctga attgggctgt ggcagctgga gccgaggatc 1250

 caggccccgc cgtggcgggc atcctctcca tccagaacat gacgacattg 1300

 ctggccaatg cctccttgaa cctgcattcc aagaagcaag ccgaactgga 1350

 ggagatatat gaaagcagca tccgtggtgt ccaactcaga cgcctctctg 1400

 ccgtcaactc catctttctg agccacaaca acaccaagga actcaactcc 1450

 cccatccttt tcgccttctc ccaccttgag tcctccgatg gggaggcggg 1500

 aagagaccct cctgccaagg acgtgatgcc tgggccacgg caggagctgc 1550

 tctgtgcctt ctggaagagt gacagcgaca ggggagggca ctgggccacc 1600

 gagggctgcc aggtgctggg cagcaagaac ggcagcacca cctgccaatg 1650

 cagccacctg agcagctttg cgatccttat ggctcattat gacgtggagg 1700

 actggaagct gaccctgatc accagggtgg gactggcgct gtcactcttc 1750

 tgcctgctgc tgtgcatcct cactttcctg ctggtgcggc ccatccaggg 1800

 ctcgcgcacc accatacacc tgcacctctg catctgcctc ttcgtgggct 1850

 ccaccatctt cctggccggc atcgagaacg aaggcggcca ggtggggctg 1900

 cgctgccgcc tggtggccgg gctgctgcac tactgtttcc tggccgcctt 1950

 ctgctggatg agcctcgaag gcctggagct ctactttctt gtggtgcgcg 2000

 tgttccaagg ccagggcctg agtacgcgct ggctctgcct gatcggctat 2050

 ggcgtgcccc tgctcatcgt gggcgtctcg gctgccatct acagcaaggg 2100

 ctacggccgc cccagatact gctggttgga ctttgagcag ggcttcctct 2150

 ggagcttctt gggacctgtg accttcatca ttttgtgcaa tgctgtcatt 2200

 ttcgtgacta ccgtctggaa gctcactcag aagttttctg aaatcaatcc 2250

 agacatgaag aaattaaaga aggcgagggc gctgaccatc acggccatcg 2300

 cgcagctctt cctgttgggc tgcacctggg tctttggcct gttcatcttc 2350

 gacgatcgga gcttggtgct gacctatgtg tttaccatcc tcaactgcct 2400

 gcagggcgcc ttcctctacc tgctgcactg cctgctcaac aagaaggttc 2450

 gggaagaata ccggaagtgg gcctgcctag ttgctggggg gagcaagtac 2500

 tcagaattca cctccaccac gtctggcact ggccacaatc agacccgggc 2550

 cctcagggca tcagagtccg gcatatgaag gcgcatggtt ctggacggcc 2600

 cagcagctcc tgtggccaca gcagctttgt acacgaagac catccatcct 2650

 cccttcgtcc accactctac tccctccacc ctccctccct gatcccgtgt 2700

 gccaccagga gggagtggca gctatagtct ggcaccaaag tccaggacac 2750

 ccagtggggt ggagtcggag ccactggtcc tgctgctggc tgcctctctg 2800

 ctccaccttg tgacccaggg tggggacagg ggctggccca gggctgcaat 2850

 gcagcatgtt gccctggcac ctgtggccag tactcgggac agactaaggg 2900

 cgcttgtccc atcctggact tttcctctca tgtctttgct gcagaactga 2950

 agagactagg cgctggggct cagcttccct cttaagctaa gactgatgtc 3000

 agaggcccca tggcgaggcc ccttggggcc actgcctgag gctcacggta 3050

 cagaggcctg ccctgcctgg ccgggcagga ggttctcact gttgtgaagg 3100

 ttgtagacgt tgtgtaatgt gtttttatct gttaaaattt ttcagtgttg 3150

 acacttaaaa ttaaacacat gcatacag 3178

<210> 754
<211> 835
<212> PRT
<213> Homo sapien

<400> 754
 Met Gly Gly Arg Val Phe Leu Ala Phe Cys Val Trp Leu Thr Leu
   1               5                  10                  15

 Pro Gly Ala Glu Thr Gln Asp Ser Arg Gly Cys Ala Arg Trp Cys
                  20                  25                  30

 Pro Gln Asn Ser Ser Cys Val Asn Ala Thr Ala Cys Arg Cys Asn
                  35                  40                  45

 Pro Gly Phe Ser Ser Phe Ser Glu Ile Ile Thr Thr Pro Thr Glu
                  50                  55                  60

 Thr Cys Asp Asp Ile Asn Glu Cys Ala Thr Pro Ser Lys Val Ser
                  65                  70                  75

 Cys Gly Lys Phe Ser Asp Cys Trp Asn Thr Glu Gly Ser Tyr Asp
                  80                  85                  90

 Cys Val Cys Ser Pro Gly Tyr Glu Pro Val Ser Gly Ala Lys Thr
                  95                 100                 105

 Phe Lys Asn Glu Ser Glu Asn Thr Cys Gln Asp Val Asp Glu Cys
                 110                 115                 120

 Gln Gln Asn Pro Arg Leu Cys Lys Ser Tyr Gly Thr Cys Val Asn
                 125                 130                 135

 Thr Leu Gly Ser Tyr Thr Cys Gln Cys Leu Pro Gly Phe Lys Phe
                 140                 145                 150

 Ile Pro Glu Asp Pro Lys Val Cys Thr Asp Val Asn Glu Cys Thr
                 155                 160                 165

 Ser Gly Gln Asn Pro Cys His Ser Ser Thr His Cys Leu Asn Asn
                 170                 175                 180

 Val Gly Ser Tyr Gln Cys Arg Cys Arg Pro Gly Trp Gln Pro Ile
                 185                 190                 195

 Pro Gly Ser Pro Asn Gly Pro Asn Asn Thr Val Cys Glu Asp Val
                 200                 205                 210

 Asp Glu Cys Ser Ser Gly Gln His Gln Cys Asp Ser Ser Thr Val
                 215                 220                 225

 Cys Phe Asn Thr Val Gly Ser Tyr Ser Cys Arg Cys Arg Pro Gly
                 230                 235                 240

 Trp Lys Pro Arg His Gly Ile Pro Asn Asn Gln Lys Asp Thr Val
                 245                 250                 255

 Cys Glu Asp Met Thr Phe Ser Thr Trp Thr Pro Pro Pro Gly Val
                 260                 265                 270

 His Ser Gln Thr Leu Ser Arg Phe Phe Asp Lys Val Gln Asp Leu
                 275                 280                 285

 Gly Arg Asp Ser Lys Thr Ser Ser Ala Glu Val Thr Ile Gln Asn
                 290                 295                 300

 Val Ile Lys Leu Val Asp Glu Leu Met Glu Ala Pro Gly Asp Val
                 305                 310                 315

 Glu Ala Leu Ala Pro Pro Val Arg His Leu Ile Ala Thr Gln Leu
                 320                 325                 330

 Leu Ser Asn Leu Glu Asp Ile Met Arg Ile Leu Ala Lys Ser Leu
                 335                 340                 345

 Pro Lys Gly Pro Phe Thr Tyr Ile Ser Pro Ser Asn Thr Glu Leu
                 350                 355                 360

 Thr Leu Met Ile Gln Glu Arg Gly Asp Lys Asn Val Thr Met Gly
                 365                 370                 375

 Gln Ser Ser Ala Arg Met Lys Leu Asn Trp Ala Val Ala Ala Gly
                 380                 385                 390

 Ala Glu Asp Pro Gly Pro Ala Val Ala Gly Ile Leu Ser Ile Gln
                 395                 400                 405

 Asn Met Thr Thr Leu Leu Ala Asn Ala Ser Leu Asn Leu His Ser
                 410                 415                 420

 Lys Lys Gln Ala Glu Leu Glu Glu Ile Tyr Glu Ser Ser Ile Arg
                 425                 430                 435

 Gly Val Gln Leu Arg Arg Leu Ser Ala Val Asn Ser Ile Phe Leu
                 440                 445                 450

 Ser His Asn Asn Thr Lys Glu Leu Asn Ser Pro Ile Leu Phe Ala
                 455                 460                 465

 Phe Ser His Leu Glu Ser Ser Asp Gly Glu Ala Gly Arg Asp Pro
                 470                 475                 480

 Pro Ala Lys Asp Val Met Pro Gly Pro Arg Gln Glu Leu Leu Cys
                 485                 490                 495

 Ala Phe Trp Lys Ser Asp Ser Asp Arg Gly Gly His Trp Ala Thr
                 500                 505                 510

 Glu Gly Cys Gln Val Leu Gly Ser Lys Asn Gly Ser Thr Thr Cys
                 515                 520                 525

 Gln Cys Ser His Leu Ser Ser Phe Ala Ile Leu Met Ala His Tyr
                 530                 535                 540

 Asp Val Glu Asp Trp Lys Leu Thr Leu Ile Thr Arg Val Gly Leu
                 545                 550                 555

 Ala Leu Ser Leu Phe Cys Leu Leu Leu Cys Ile Leu Thr Phe Leu
                 560                 565                 570

 Leu Val Arg Pro Ile Gln Gly Ser Arg Thr Thr Ile His Leu His
                 575                 580                 585

 Leu Cys Ile Cys Leu Phe Val Gly Ser Thr Ile Phe Leu Ala Gly
                 590                 595                 600

 Ile Glu Asn Glu Gly Gly Gln Val Gly Leu Arg Cys Arg Leu Val
                 605                 610                 615

 Ala Gly Leu Leu His Tyr Cys Phe Leu Ala Ala Phe Cys Trp Met
                 620                 625                 630

 Ser Leu Glu Gly Leu Glu Leu Tyr Phe Leu Val Val Arg Val Phe
                 635                 640                 645

 Gln Gly Gln Gly Leu Ser Thr Arg Trp Leu Cys Leu Ile Gly Tyr
                 650                 655                 660

 Gly Val Pro Leu Leu Ile Val Gly Val Ser Ala Ala Ile Tyr Ser
                 665                 670                 675

 Lys Gly Tyr Gly Arg Pro Arg Tyr Cys Trp Leu Asp Phe Glu Gln
                 680                 685                 690

 Gly Phe Leu Trp Ser Phe Leu Gly Pro Val Thr Phe Ile Ile Leu
                 695                 700                 705

 Cys Asn Ala Val Ile Phe Val Thr Thr Val Trp Lys Leu Thr Gln
                 710                 715                 720

 Lys Phe Ser Glu Ile Asn Pro Asp Met Lys Lys Leu Lys Lys Ala
                 725                 730                 735

 Arg Ala Leu Thr Ile Thr Ala Ile Ala Gln Leu Phe Leu Leu Gly
                 740                 745                 750

 Cys Thr Trp Val Phe Gly Leu Phe Ile Phe Asp Asp Arg Ser Leu
                 755                 760                 765

 Val Leu Thr Tyr Val Phe Thr Ile Leu Asn Cys Leu Gln Gly Ala
                 770                 775                 780

 Phe Leu Tyr Leu Leu His Cys Leu Leu Asn Lys Lys Val Arg Glu
                 785                 790                 795

 Glu Tyr Arg Lys Trp Ala Cys Leu Val Ala Gly Gly Ser Lys Tyr
                 800                 805                 810

 Ser Glu Phe Thr Ser Thr Thr Ser Gly Thr Gly His Asn Gln Thr
                 815                 820                 825

 Arg Ala Leu Arg Ala Ser Glu Ser Gly Ile
                 830                 835

<210> 755
<211> 4264
<212> DNA
<213> Homo sapien

<400> 755
 atttcccgcc agcaggagcc gcgcggtaga tgcggtgctt ttaggagctc 50

 cgtccgacag aacggttggg ccttgccggc tgtcggtatg tcgcgacaga 100

 gcaccctgta cagcttcttc cccaagtctc cggcgctgag tgatgccaac 150

 aaggcctcgg ccagggcctc acgcgaaggc ggccgtgccg ccgctgcccc 200

 cggggcctct ccttccccag gcggggatgc ggcctggagc gaggctgggc 250

 ctgggcccag gcccttggcg cgatccgcgt caccgcccaa ggcgaagaac 300

 ctcaacggag ggctgcggag atcggtagcg cctgctgccc ccaccagttg 350

 tgacttctca ccaggagatt tggtttgggc caagatggag ggttacccct 400

 ggtggccttg tctggtttac aaccacccct ttgatggaac attcatccgc 450

 gagaaaggga aatcagtccg tgttcatgta cagttttttg atgacagccc 500

 aacaaggggc tgggttagca aaaggctttt aaagccatat acaggttcaa 550

 aatcaaagga agcccagaag ggaggtcatt tttacagtgc aaagcctgaa 600

 atactgagag caatgcaacg tgcagatgaa gccttaaata aagacaagat 650

 taagaggctt gaattggcag tttgtgatga gccctcagag ccagaagagg 700

 aagaagagat ggaggtaggc acaacttacg taacagataa gagtgaagaa 750

 gataatgaaa ttgagagtga agaggaagta cagcctaaga cacaaggatc 800

 taggcgaagt agccgccaaa taaaaaaacg aagggtcata tcagattctg 850

 agagtgacat tggtggctct gatgtggaat ttaagccaga cactaaggag 900

 gaaggaagca gtgatgaaat aagcagtgga gtgggggata gtgagagtga 950

 aggcctgaac agccctgtca aagttgctcg aaagcggaag agaatggtga 1000

 ctggaaatgg ctctcttaaa aggaaaagct ctaggaagga aacgccctca 1050

 gccaccaaac aagcaactag catttcatca gaaaccaaga atactttgag 1100

 agctttctct gcccctcaaa attctgaatc ccaagcccac gttagtggag 1150

 gtggtgatga cagtagtcgc cctactgttt ggtatcatga aactttagaa 1200

 tggcttaagg aggaaaagag aagagatgag cacaggagga ggcctgatca 1250

 ccccgatttt gatgcatcta cactctatgt gcctgaggat ttcctcaatt 1300

 cttgtactcc tgggatgagg aagtggtggc agattaagtc tcagaacttt 1350

 gatcttgtca tctgttacaa ggtggggaaa ttttatgagc tgtaccacat 1400

 ggatgctctt attggagtca gtgaactggg gctggtattc atgaaaggca 1450

 actgggccca ttctggcttt cctgaaattg catttggccg ttattcagat 1500

 tccctggtgc agaagggcta taaagtagca cgagtggaac agactgagac 1550

 tccagaaatg atggaggcac gatgtagaaa gatggcacat atatccaagt 1600

 atgatagagt ggtgaggagg gagatctgta ggatcattac caagggtaca 1650

 cagacttaca gtgtgctgga aggtgatccc tctgagaact acagtaagta 1700

 tcttcttagc ctcaaagaaa aagaggaaga ttcttctggc catactcgtg 1750

 catatggtgt gtgctttgtt gatacttcac tgggaaagtt tttcataggt 1800

 cagttttcag atgatcgcca ttgttcgaga tttaggactc tagtggcaca 1850

 ctatccccca gtacaagttt tatttgaaaa aggaaatctc tcaaaggaaa 1900

 ctaaaacaat tctaaagagt tcattgtcct gttctcttca ggaaggtctg 1950

 atacccggct cccagttttg ggatgcatcc aaaactttga gaactctcct 2000

 tgaggaagaa tattttaggg aaaagctaag tgatggcatt ggggtgatgt 2050

 taccccaggt gcttaaaggt atgacttcag agtctgattc cattgggttg 2100

 acaccaggag agaaaagtga attggccctc tctgctctag gtggttgtgt 2150

 cttctacctc aaaaaatgcc ttattgatca ggagctttta tcaatggcta 2200

 attttgaaga atatattccc ttggattctg acacagtcag cactacaaga 2250

 tctggtgcta tcttcaccaa agcctatcaa cgaatggtgc tagatgcagt 2300

 gacattaaac aacttggaga tttttctgaa tggaacaaat ggttctactg 2350

 aaggaaccct actagagagg gttgatactt gccatactcc ttttggtaag 2400

 cggctcctaa agcaatggct ttgtgcccca ctctgtaacc attatgctat 2450

 taatgatcgt ctagatgcca tagaagacct catggttgtg cctgacaaaa 2500

 tctccgaagt tgtagagctt ctaaagaagc ttccagatct tgagaggcta 2550

 ctcagtaaaa ttcataatgt tgggtctccc ctgaagagtc agaaccaccc 2600

 agacagcagg gctataatgt atgaagaaac tacatacagc aagaagaaga 2650

 ttattgattt tctttctgct ctggaaggat tcaaagtaat gtgtaaaatt 2700

 atagggatca tggaagaagt tgctgatggt tttaagtcta aaatccttaa 2750

 gcaggtcatc tctctgcaga caaaaaatcc tgaaggtcgt tttcctgatt 2800

 tgactgtaga attgaaccga tgggatacag cctttgacca tgaaaaggct 2850

 cgaaagactg gacttattac tcccaaagca ggctttgact ctgattatga 2900

 ccaagctctt gctgacataa gagaaaatga acagagcctc ctggaatacc 2950

 tagagaaaca gcgcaacaga attggctgta ggaccatagt ctattggggg 3000

 attggtagga accgttacca gctggaaatt cctgagaatt tcaccactcg 3050

 caatttgcca gaagaatacg agttgaaatc taccaagaag ggctgtaaac 3100

 gatactggac caaaactatt gaaaagaagt tggctaatct cataaatgct 3150

 gaagaacgga gggatgtatc attgaaggac tgcatgcggc gactgttcta 3200

 taactttgat aaaaattaca aggactggca gtctgctgta gagtgtatcg 3250

 cagtgttgga tgttttactg tgcctggcta actatagtcg agggggtgat 3300

 ggtcctatgt gtcgcccagt aattctgttg ccggaagata cccccccctt 3350

 cttagagctt aaaggatcac gccatccttg cattacgaag actttttttg 3400

 gagatgattt tattcctaat gacattctaa taggctgtga ggaagaggag 3450

 caggaaaatg gcaaagccta ttgtgtgctt gttactggac caaatatggg 3500

 gggcaagtct acgcttatga gacaggctgg cttattagct gtaatggccc 3550

 agatgggttg ttacgtccct gctgaagtgt gcaggctcac accaattgat 3600

 agagtgttta ctagacttgg tgcctcagac agaataatgt caggtgaaag 3650

 tacatttttt gttgaattaa gtgaaactgc cagcatactc atgcatgcaa 3700

 cagcacattc tctggtgctt gtggatgaat taggaagagg tactgcaaca 3750

 tttgatggga cggcaatagc aaatgcagtt gttaaagaac ttgctgagac 3800

 tataaaatgt cgtacattat tttcaactca ctaccattca ttagtagaag 3850

 attattctca aaatgttgct gtgcgcctag gacatatggc atgcatggta 3900

 gaaaatgaat gtgaagaccc cagccaggag actattacgt tcctctataa 3950

 attcattaag ggagcttgtc ctaaaagcta tggctttaat gcagcaaggc 4000

 ttgctaatct cccagaggaa gttattcaaa agggacatag aaaagcaaga 4050

 gaatttgaga agatgaatca gtcactacga ttatttcggg aagtttgcct 4100

 ggctagtgaa aggtcaactg tagatgctga agctgtccat aaattgctga 4150

 ctttgattaa ggaattatag actgactaca ttggaagctt tgagttgact 4200

 tctgaccaaa ggtggtaaat tcagacaaca ttatgatcta ataaacttta 4250

 ttttttaaaa atga 4264

<210> 756
<211> 1360
<212> PRT
<213> Homo sapien

<400> 756
 Met Ser Arg Gln Ser Thr Leu Tyr Ser Phe Phe Pro Lys Ser Pro
   1               5                  10                  15

 Ala Leu Ser Asp Ala Asn Lys Ala Ser Ala Arg Ala Ser Arg Glu
                  20                  25                  30

 Gly Gly Arg Ala Ala Ala Ala Pro Gly Ala Ser Pro Ser Pro Gly
                  35                  40                  45

 Gly Asp Ala Ala Trp Ser Glu Ala Gly Pro Gly Pro Arg Pro Leu
                  50                  55                  60

 Ala Arg Ser Ala Ser Pro Pro Lys Ala Lys Asn Leu Asn Gly Gly
                  65                  70                  75

 Leu Arg Arg Ser Val Ala Pro Ala Ala Pro Thr Ser Cys Asp Phe
                  80                  85                  90

 Ser Pro Gly Asp Leu Val Trp Ala Lys Met Glu Gly Tyr Pro Trp
                  95                 100                 105

 Trp Pro Cys Leu Val Tyr Asn His Pro Phe Asp Gly Thr Phe Ile
                 110                 115                 120

 Arg Glu Lys Gly Lys Ser Val Arg Val His Val Gln Phe Phe Asp
                 125                 130                 135

 Asp Ser Pro Thr Arg Gly Trp Val Ser Lys Arg Leu Leu Lys Pro
                 140                 145                 150

 Tyr Thr Gly Ser Lys Ser Lys Glu Ala Gln Lys Gly Gly His Phe
                 155                 160                 165

 Tyr Ser Ala Lys Pro Glu Ile Leu Arg Ala Met Gln Arg Ala Asp
                 170                 175                 180

 Glu Ala Leu Asn Lys Asp Lys Ile Lys Arg Leu Glu Leu Ala Val
                 185                 190                 195

 Cys Asp Glu Pro Ser Glu Pro Glu Glu Glu Glu Glu Met Glu Val
                 200                 205                 210

 Gly Thr Thr Tyr Val Thr Asp Lys Ser Glu Glu Asp Asn Glu Ile
                 215                 220                 225

 Glu Ser Glu Glu Glu Val Gln Pro Lys Thr Gln Gly Ser Arg Arg
                 230                 235                 240

 Ser Ser Arg Gln Ile Lys Lys Arg Arg Val Ile Ser Asp Ser Glu
                 245                 250                 255

 Ser Asp Ile Gly Gly Ser Asp Val Glu Phe Lys Pro Asp Thr Lys
                 260                 265                 270

 Glu Glu Gly Ser Ser Asp Glu Ile Ser Ser Gly Val Gly Asp Ser
                 275                 280                 285

 Glu Ser Glu Gly Leu Asn Ser Pro Val Lys Val Ala Arg Lys Arg
                 290                 295                 300

 Lys Arg Met Val Thr Gly Asn Gly Ser Leu Lys Arg Lys Ser Ser
                 305                 310                 315

 Arg Lys Glu Thr Pro Ser Ala Thr Lys Gln Ala Thr Ser Ile Ser
                 320                 325                 330

 Ser Glu Thr Lys Asn Thr Leu Arg Ala Phe Ser Ala Pro Gln Asn
                 335                 340                 345

 Ser Glu Ser Gln Ala His Val Ser Gly Gly Gly Asp Asp Ser Ser
                 350                 355                 360

 Arg Pro Thr Val Trp Tyr His Glu Thr Leu Glu Trp Leu Lys Glu
                 365                 370                 375

 Glu Lys Arg Arg Asp Glu His Arg Arg Arg Pro Asp His Pro Asp
                 380                 385                 390

 Phe Asp Ala Ser Thr Leu Tyr Val Pro Glu Asp Phe Leu Asn Ser
                 395                 400                 405

 Cys Thr Pro Gly Met Arg Lys Trp Trp Gln Ile Lys Ser Gln Asn
                 410                 415                 420

 Phe Asp Leu Val Ile Cys Tyr Lys Val Gly Lys Phe Tyr Glu Leu
                 425                 430                 435

 Tyr His Met Asp Ala Leu Ile Gly Val Ser Glu Leu Gly Leu Val
                 440                 445                 450

 Phe Met Lys Gly Asn Trp Ala His Ser Gly Phe Pro Glu Ile Ala
                 455                 460                 465

 Phe Gly Arg Tyr Ser Asp Ser Leu Val Gln Lys Gly Tyr Lys Val
                 470                 475                 480

 Ala Arg Val Glu Gln Thr Glu Thr Pro Glu Met Met Glu Ala Arg
                 485                 490                 495

 Cys Arg Lys Met Ala His Ile Ser Lys Tyr Asp Arg Val Val Arg
                 500                 505                 510

 Arg Glu Ile Cys Arg Ile Ile Thr Lys Gly Thr Gln Thr Tyr Ser
                 515                 520                 525

 Val Leu Glu Gly Asp Pro Ser Glu Asn Tyr Ser Lys Tyr Leu Leu
                 530                 535                 540

 Ser Leu Lys Glu Lys Glu Glu Asp Ser Ser Gly His Thr Arg Ala
                 545                 550                 555

 Tyr Gly Val Cys Phe Val Asp Thr Ser Leu Gly Lys Phe Phe Ile
                 560                 565                 570

 Gly Gln Phe Ser Asp Asp Arg His Cys Ser Arg Phe Arg Thr Leu
                 575                 580                 585

 Val Ala His Tyr Pro Pro Val Gln Val Leu Phe Glu Lys Gly Asn
                 590                 595                 600

 Leu Ser Lys Glu Thr Lys Thr Ile Leu Lys Ser Ser Leu Ser Cys
                 605                 610                 615

 Ser Leu Gln Glu Gly Leu Ile Pro Gly Ser Gln Phe Trp Asp Ala
                 620                 625                 630

 Ser Lys Thr Leu Arg Thr Leu Leu Glu Glu Glu Tyr Phe Arg Glu
                 635                 640                 645

 Lys Leu Ser Asp Gly Ile Gly Val Met Leu Pro Gln Val Leu Lys
                 650                 655                 660

 Gly Met Thr Ser Glu Ser Asp Ser Ile Gly Leu Thr Pro Gly Glu
                 665                 670                 675

 Lys Ser Glu Leu Ala Leu Ser Ala Leu Gly Gly Cys Val Phe Tyr
                 680                 685                 690

 Leu Lys Lys Cys Leu Ile Asp Gln Glu Leu Leu Ser Met Ala Asn
                 695                 700                 705

 Phe Glu Glu Tyr Ile Pro Leu Asp Ser Asp Thr Val Ser Thr Thr
                 710                 715                 720

 Arg Ser Gly Ala Ile Phe Thr Lys Ala Tyr Gln Arg Met Val Leu
                 725                 730                 735

 Asp Ala Val Thr Leu Asn Asn Leu Glu Ile Phe Leu Asn Gly Thr
                 740                 745                 750

 Asn Gly Ser Thr Glu Gly Thr Leu Leu Glu Arg Val Asp Thr Cys
                 755                 760                 765

 His Thr Pro Phe Gly Lys Arg Leu Leu Lys Gln Trp Leu Cys Ala
                 770                 775                 780

 Pro Leu Cys Asn His Tyr Ala Ile Asn Asp Arg Leu Asp Ala Ile
                 785                 790                 795

 Glu Asp Leu Met Val Val Pro Asp Lys Ile Ser Glu Val Val Glu
                 800                 805                 810

 Leu Leu Lys Lys Leu Pro Asp Leu Glu Arg Leu Leu Ser Lys Ile
                 815                 820                 825

 His Asn Val Gly Ser Pro Leu Lys Ser Gln Asn His Pro Asp Ser
                 830                 835                 840

 Arg Ala Ile Met Tyr Glu Glu Thr Thr Tyr Ser Lys Lys Lys Ile
                 845                 850                 855

 Ile Asp Phe Leu Ser Ala Leu Glu Gly Phe Lys Val Met Cys Lys
                 860                 865                 870

 Ile Ile Gly Ile Met Glu Glu Val Ala Asp Gly Phe Lys Ser Lys
                 875                 880                 885

 Ile Leu Lys Gln Val Ile Ser Leu Gln Thr Lys Asn Pro Glu Gly
                 890                 895                 900

 Arg Phe Pro Asp Leu Thr Val Glu Leu Asn Arg Trp Asp Thr Ala
                 905                 910                 915

 Phe Asp His Glu Lys Ala Arg Lys Thr Gly Leu Ile Thr Pro Lys
                 920                 925                 930

 Ala Gly Phe Asp Ser Asp Tyr Asp Gln Ala Leu Ala Asp Ile Arg
                 935                 940                 945

 Glu Asn Glu Gln Ser Leu Leu Glu Tyr Leu Glu Lys Gln Arg Asn
                 950                 955                 960

 Arg Ile Gly Cys Arg Thr Ile Val Tyr Trp Gly Ile Gly Arg Asn
                 965                 970                 975

 Arg Tyr Gln Leu Glu Ile Pro Glu Asn Phe Thr Thr Arg Asn Leu
                 980                 985                 990

 Pro Glu Glu Tyr Glu Leu Lys Ser Thr Lys Lys Gly Cys Lys Arg
                 995                1000                1005

 Tyr Trp Thr Lys Thr Ile Glu Lys Lys Leu Ala Asn Leu Ile Asn
                1010                1015                1020

 Ala Glu Glu Arg Arg Asp Val Ser Leu Lys Asp Cys Met Arg Arg
                1025                1030                1035

 Leu Phe Tyr Asn Phe Asp Lys Asn Tyr Lys Asp Trp Gln Ser Ala
                1040                1045                1050

 Val Glu Cys Ile Ala Val Leu Asp Val Leu Leu Cys Leu Ala Asn
                1055                1060                1065

 Tyr Ser Arg Gly Gly Asp Gly Pro Met Cys Arg Pro Val Ile Leu
                1070                1075                1080

 Leu Pro Glu Asp Thr Pro Pro Phe Leu Glu Leu Lys Gly Ser Arg
                1085                1090                1095

 His Pro Cys Ile Thr Lys Thr Phe Phe Gly Asp Asp Phe Ile Pro
                1100                1105                1110

 Asn Asp Ile Leu Ile Gly Cys Glu Glu Glu Glu Gln Glu Asn Gly
                1115                1120                1125

 Lys Ala Tyr Cys Val Leu Val Thr Gly Pro Asn Met Gly Gly Lys
                1130                1135                1140

 Ser Thr Leu Met Arg Gln Ala Gly Leu Leu Ala Val Met Ala Gln
                1145                1150                1155

 Met Gly Cys Tyr Val Pro Ala Glu Val Cys Arg Leu Thr Pro Ile
                1160                1165                1170

 Asp Arg Val Phe Thr Arg Leu Gly Ala Ser Asp Arg Ile Met Ser
                1175                1180                1185

 Gly Glu Ser Thr Phe Phe Val Glu Leu Ser Glu Thr Ala Ser Ile
                1190                1195                1200

 Leu Met His Ala Thr Ala His Ser Leu Val Leu Val Asp Glu Leu
                1205                1210                1215

 Gly Arg Gly Thr Ala Thr Phe Asp Gly Thr Ala Ile Ala Asn Ala
                1220                1225                1230

 Val Val Lys Glu Leu Ala Glu Thr Ile Lys Cys Arg Thr Leu Phe
                1235                1240                1245

 Ser Thr His Tyr His Ser Leu Val Glu Asp Tyr Ser Gln Asn Val
                1250                1255                1260

 Ala Val Arg Leu Gly His Met Ala Cys Met Val Glu Asn Glu Cys
                1265                1270                1275

 Glu Asp Pro Ser Gln Glu Thr Ile Thr Phe Leu Tyr Lys Phe Ile
                1280                1285                1290

 Lys Gly Ala Cys Pro Lys Ser Tyr Gly Phe Asn Ala Ala Arg Leu
                1295                1300                1305

 Ala Asn Leu Pro Glu Glu Val Ile Gln Lys Gly His Arg Lys Ala
                1310                1315                1320

 Arg Glu Phe Glu Lys Met Asn Gln Ser Leu Arg Leu Phe Arg Glu
                1325                1330                1335

 Val Cys Leu Ala Ser Glu Arg Ser Thr Val Asp Ala Glu Ala Val
                1340                1345                1350

 His Lys Leu Leu Thr Leu Ile Lys Glu Leu
                1355                1360

<210> 757
<211> 1449
<212> DNA
<213> Homo sapien

<400> 757
 ctggatagaa cagctcaagc cttgccactt cgggcttctc actgcagctg 50

 ggcttggact tcggagtttt gccattgcca gtgggacgtc tgagactttc 100

 tccttcaagt acttggcaga tcactctctt agcagggtct gcgcttcgca 150

 gccgggatga agctggtttc cgtcgccctg atgtacctgg gttcgctcgc 200

 cttcctaggc gctgacaccg ctcggttgga tgtcgcgtcg gagtttcgaa 250

 agaagtggaa taagtgggct ctgagtcgtg ggaagaggga actgcggatg 300

 tccagcagct accccaccgg gctcgctgac gtgaaggccg ggcctgccca 350

 gacccttatt cggccccagg acatgaaggg tgcctctcga agccccgaag 400

 acagcagtcc ggatgccgcc cgcatccgag tcaagcgcta ccgccagagc 450

 atgaacaact tccagggcct ccggagcttt ggctgccgct tcgggacgtg 500

 cacggtgcag aagctggcac accagatcta ccagttcaca gataaggaca 550

 aggacaacgt cgcccccagg agcaagatca gcccccaggg ctacggccgc 600

 cggcgccggc gctccctgcc cgaggccggc ccgggtcgga ctctggtgtc 650

 ttctaagcca caagcacacg gggctccagc ccccccgagt ggaagtgctc 700

 cccactttct ttaggattta ggcgcccatg gtacaaggaa tagtcgcgca 750

 agcatcccgc tggtgcctcc cgggacgaag gacttcccga gcggtgtggg 800

 gaccgggctc tgacagccct gcggagaccc tgagtccggg aggcaccgtc 850

 cggcggcgag ctctggcttt gcaagggccc ctccttctgg gggcttcgct 900

 tccttagcct tgctcaggtg caagtgcccc agggggcggg gtgcagaaga 950

 atccgagtgt ttgccaggct taaggagagg agaaactgag aaatgaatgc 1000

 tgagaccccc ggagcagggg tctgagccac agccgtgctc gcccacaaac 1050

 tgatttctca cggcgtgtca ccccaccagg gcgcaagcct cactattact 1100

 tgaactttcc aaaacctaaa gaggaaaagt gcaatgcgtg ttgtacatac 1150

 agaggtaact atcaatattt aagtttgttg ctgtcaagat tttttttgta 1200

 acttcaaata tagagatatt tttgtacgtt atatattgta ttaagggcat 1250

 tttaaaagca attatattgt cctcccctat tttaagacgt gaatgtctca 1300

 gcgaggtgta aagttgttcg ccgcgtggaa tgtgagtgtg tttgtgtgca 1350

 tgaaagagaa agactgatta cctcctgtgt ggaagaagga aacaccgagt 1400

 ctctgtataa tctatttaca taaaatgggt gatatgcgaa cagcaaacc 1449

<210> 758
<211> 185
<212> PRT
<213> Homo sapien

<400> 758
 Met Lys Leu Val Ser Val Ala Leu Met Tyr Leu Gly Ser Leu Ala
   1               5                  10                  15

 Phe Leu Gly Ala Asp Thr Ala Arg Leu Asp Val Ala Ser Glu Phe
                  20                  25                  30

 Arg Lys Lys Trp Asn Lys Trp Ala Leu Ser Arg Gly Lys Arg Glu
                  35                  40                  45

 Leu Arg Met Ser Ser Ser Tyr Pro Thr Gly Leu Ala Asp Val Lys
                  50                  55                  60

 Ala Gly Pro Ala Gln Thr Leu Ile Arg Pro Gln Asp Met Lys Gly
                  65                  70                  75

 Ala Ser Arg Ser Pro Glu Asp Ser Ser Pro Asp Ala Ala Arg Ile
                  80                  85                  90

 Arg Val Lys Arg Tyr Arg Gln Ser Met Asn Asn Phe Gln Gly Leu
                  95                 100                 105

 Arg Ser Phe Gly Cys Arg Phe Gly Thr Cys Thr Val Gln Lys Leu
                 110                 115                 120

 Ala His Gln Ile Tyr Gln Phe Thr Asp Lys Asp Lys Asp Asn Val
                 125                 130                 135

 Ala Pro Arg Ser Lys Ile Ser Pro Gln Gly Tyr Gly Arg Arg Arg
                 140                 145                 150

 Arg Arg Ser Leu Pro Glu Ala Gly Pro Gly Arg Thr Leu Val Ser
                 155                 160                 165

 Ser Lys Pro Gln Ala His Gly Ala Pro Ala Pro Pro Ser Gly Ser
                 170                 175                 180

 Ala Pro His Phe Leu
                 185

<210> 759
<211> 5789
<212> DNA
<213> Homo sapien

<400> 759
 ggcgggccgc ggccccgcga gccgtgagcg atgatttggc gttgcggcca 50

 cggcggcagg gcggtccgtg gggcgcacac accctccccg cgcagccaat 100

 gggcgtgcgc acgtcactga tccggaggcc cgcgggccgg cagcccctca 150

 ataagccaca ttgttgcatg aaactccggc gcaggagtcc cgggctgccg 200

 ctggcaacat cgtgtcaccc agctaagaaa atccgcgggc ccgagccacg 250

 cgcctgtgaa tcggagaggt cccactgccc gagtggagcc gggctgagat 300

 tcttctcaag ttgagcctca gtgatcctgt ggccgaagtt agcgccttga 350

 cgtgggacaa ccggacacgt cgccaggaga gaactgaggc gccttctagc 400

 agttgtgacg ccaaaatcac gtctccggag acccgcgccc tccgccagcc 450

 gggcgcaccc tcgccggtag ccttctttgt gcgccgtccg gactcccagc 500

 tcccggcccg gcagccgagc cccagcacaa agcagtcgga ccgcgccgcc 550

 cgcctcccct ctcgcgtctc cgcctcggtt tcccaactct gcgccgtcgg 600

 gccgcggcag gatgattgcc tcgcatctgc ttgcctactt cttcacggag 650

 ctcaaccatg accaagtgca gaaggttgac cagtatctct accacatgcg 700

 cctctctgat gagaccctct tggagatctc taagcggttc cgcaaggaga 750

 tggagaaagg gcttggagcc accactcacc ctactgcagc agtgaagatg 800

 ctgcccacct ttgtgaggtc cactccagat gggacagaac acggagagtt 850

 cctggctctg gatcttggag ggaccaactt ccgtgtgctt tgggtgaaag 900

 taacggacaa tgggctccag aaggtggaga tggagaatca gatctatgcc 950

 atccctgagg acatcatgcg aggcagtggc acccagctgt ttgaccacat 1000

 tgccgaatgc ctggctaact tcatggataa gctacaaatc aaagacaaga 1050

 agctcccact gggttttacc ttctcgttcc cctgccacca gactaaacta 1100

 gacgagagtt tcctggtctc atggaccaag ggattcaagt ccagtggagt 1150

 ggaaggcaga gacgttgtgg ctctgatccg gaaggccatc cagaggagag 1200

 gggactttga tatcgacatt gtggctgtgg tgaatgacac agttgggacc 1250

 atgatgacct gtggttatga tgaccacaac tgtgagattg gtctcattgt 1300

 gggcacgggg cagcaacgcc tgctacatgg aagagatgcg ccacatcgac 1350

 atggtggaag gcgatgaggg gcggatgtgt atcaatatgg agtggggggc 1400

 cttcggggac gatggctcgc tcaacgacat tcgcactgag tttgaccagg 1450

 agattgacat gggctcactg aacccgggaa agcaactgtt tgagaagatg 1500

 atcagtggga tgtacatggg ggagctggtg aggcttatcc tggtgaagat 1550

 ggccaaggag gagctgctct ttggggggaa gctcagccca gagcttctca 1600

 acaccggtcg ctttgagacc aaagacatct cagacattga aggggagaag 1650

 gatggcatcc ggaaggcccg tgaggtcctg atgcggttgg gcctggaccc 1700

 gactcaggag gactgcgtgg ccactcaccg gatctgccag atcgtgtcca 1750

 cacgctccgc cagcctgtgc gcagccaccc tggccgccgt gctgcagcgc 1800

 atcaaggaga acaaaggcga ggagcggctg cgctctacta ttggggtcga 1850

 cggttccgtc tacaagaaac acccccattt tgccaagcgt ctacataaga 1900

 ccgtgcggcg gctggtgccc ggctgcgatg tccgcttcct ccgctccgag 1950

 gatggcagtg gcaaaggtgc agccatggtg acagcagtgg cttaccggct 2000

 ggccgatcaa caccgtgccc gccagaagac attagagcat ctgcagctga 2050

 gccatgacca gctgctggag gtcaagagga ggatgaaggt agaaatggag 2100

 cgaggtctga gcaaggagac tcatgccagt gcccccgtca agatgctgcc 2150

 cacctacgtg tgtgctaccc cggacggcac agagaaaggg gacttcttgg 2200

 ccttggacct tggaggaaca aatttccggg tcctgctggt ccgtgttcgg 2250

 aatgggaagt ggggtggagt ggagatgcac aacaagatct acgccatccc 2300

 gcaggaggtc atgcacggca ccggggacga gctctttgac cacattgtcc 2350

 agtgcatcgc ggacttcctc gagtacatgg gcatgaaggg cgtgtccctg 2400

 cctctgggtt ttaccttctc cttcccctgc cagcagaaca gcctggacga 2450

 gagcatcctc ctcaagtgga caaaaggctt caaggcatct ggctgcgagg 2500

 gcgaggacgt ggtgaccctg ctgaaggaag cgatccaccg gcgagaggag 2550

 tttgacctgg atgtggttgc tgtggtgaac gacacagtcg gaactatgat 2600

 gacctgtggc tttgaagacc ctcactgtga agttggcctc attgttggca 2650

 cgggcagcaa tgcctgctac atggaggaga tgcgcaacgt ggaactggtg 2700

 gaaggagaag aggggcggat gtgtgtgaac atggaatggg gggccttcgg 2750

 ggacaatgga tgcctagatg acttccgcac agaatttgat gtggctgtgg 2800

 atgagctttc actcaacccg ggcaagcaga ggttcgagaa aatgatcagt 2850

 ggaatgtacc tgggtgagat tgtccgtaac attctcatcg atttcaccaa 2900

 gcgtggactg ctcttccgag gccgcatctc agagcggctc aagacaaggg 2950

 gcatctttga aaccaagttc ttgtctcaga ttgagagtga ctgcctggcc 3000

 ctgctgcaag tccgagccat cctgcaacac ttagggcttg agagcacctg 3050

 tgacgacagc atcattgtta aggaggtgtg cactgtggtg gcccggcggg 3100

 cagcccagct ctgtggcgca ggcatggccg ctgtggtgga caggatacga 3150

 gaaaaccgtg ggctggacgc tctcaaagtg acagtgggtg tggatgggac 3200

 cctctacaag ctacatcctc actttgccaa agtcatgcat gagacagtga 3250

 aggacctggc tccgaaatgt gatgtgtctt tcctgcagtc agaggatggc 3300

 agcgggaagg gggcggcgct catcactgct gtggcctgcc gcatccgtga 3350

 ggctggacag cgatagaacc cctgaaatcg gaagggactt cctctttctc 3400

 tccttcttcc ctgttttaaa ttataagatg tcatcccctt gtgtcagaga 3450

 cagacccctt ggcttttgct tggcagagag gaccccactg gactgggttt 3500

 tgtctctgca tctcattgta gagcttggtg gctgagcttg gccctattaa 3550

 gataaataga gttccaaata aggatttgtt cacatgcatc ataaccattc 3600

 ccattggttc tcctaaaaca tgaaaattat ctcccttagt aatccccctt 3650

 gccaaattcc atgtccctgt ataattctac aggatgggga cactaatgaa 3700

 gatacggttg cttcaccttg gagcctgaac atgacatttc taagtggggt 3750

 gcatccccca gcactgatgt tgttactgat tctcctgtca gagatctggg 3800

 aggtctccac tgaggatgtg agcctgatta tcctataggc agacgtgggg 3850

 agggtggagg ggtgacagtg gaggaaaatc catggatatc cacgcagcag 3900

 cccctcttta acctcatcta caagcatttg ccctgtggat tccagcattt 3950

 gccattcctg gaatcaagga atcctgagtc tgggcaatga aaccaaagcc 4000

 aggagttgac gcatcctgca gttgggccag ctgtcgcatc tcagcggggc 4050

 gcacatgtta tccacaagca atggaccttt ggggaagggg gagtttttag 4100

 tttgttttac aaatttttcc tgcaaaagtg gaatcactgt attttcattt 4150

 taatttatat ttgaaatttt atttagttct tgagtagatc tgcttcttca 4200

 tcttgacatg taatgaatgg tcagttgtac gtaatgtatt tatatgttaa 4250

 tttgttatgt atatagatgt gcaagtcttg tcagaattgg cctcagtgta 4300

 gttaaagggc agaaggggaa gatactgact agtcatagaa atacctcatt 4350

 cgcctgtggg aagagaaggg aagcctcttc agggtgagtg aatggcaaag 4400

 cggttgcttc tggctcctcc ttcccctgtg gtcttggaag tgtgtggaag 4450

 gcagggacag agatggaggc cgagccaata gactgaagag accacagcaa 4500

 ttggctcctc catctagaga ttttcttggc agtattccat gggatgttaa 4550

 gcaaaggaaa ccaaaggaat cgtttcaaat ggactcatgg cttagaaatc 4600

 tttattctta gggcagtcag tagtattcta aagctttctg acaagataaa 4650

 ggaagtcacc aaaatttctt tttttaaatt gtatctaatc ctcaacaaca 4700

 aaccaaaaca gaacaattaa acagccaaat aaaacctcag ggacaacatt 4750

 tttggtgtat ttgagccctc ccagcaagtt tcaccttggg tttgtatttt 4800

 aaatgtttta caagaattgt ccatgtgctt ccctaggctg agctggcatt 4850

 ggtctgctga cctgtttttg tgtttttctt ttttttatac acaacattta 4900

 tttcaaacta ttgggaggga tgagagtggc ttaaaaactt ccatccctac 4950

 ttttcaagag tgcagttgat tctgaatctg aaagcccgcc tctgtcctaa 5000

 aatacaaaca agcacagaca ttaaacctgg atactatatg ataaagaggg 5050

 atgtaactat tgaattggat acaaggatca gaatggaaag aaactcacga 5100

 tgaaattgaa cctggttttt gtatatttat caaacttgtg ctgagaatag 5150

 tgtctgatta tacgactttt aagcaaagtt gggtgtaatt aggtgaaaac 5200

 agcccaggtc ctcccgggag cacagagggg ctaggggctg gtccttctcg 5250

 tttgctctag tcttgctttg ctgtctggtg tagctcctct gctgctccca 5300

 tctgcactaa ttgacccaaa acgtgggtat ttcctgctac acaaaagcca 5350

 aaaggtttca tgtagatttt agttcactaa agggtgccca caaaatagag 5400

 attaatttta acttaaattt taagcttgaa gattaggtac tatctgtgaa 5450

 gttacacttt ttttttttaa aggtagagat gtgtgtgtgt gtaggtatta 5500

 aagatgtgtt gttggtttcc aaaaaggaac actggaaaat aaattttgaa 5550

 tgtttatgtt ctcagaatca ggttgacagt cccttgctga catggctttg 5600

 ctttgtgtaa atacagtgga tctcaatctt cggggtgtga tgaatagcga 5650

 atcatctcaa atccttgagc actcagtcta gtgaagatgt tgtcattatg 5700

 tacaatacat aactagttta attaactatg tgatgttaac tattattaat 5750

 aaattttaac attttccaaa ataaaaaata aagtcgacg 5789

<210> 760
<211> 698
<212> PRT
<213> Homo sapien

<400> 760
 Met Thr Thr Thr Val Arg Leu Val Ser Leu Trp Ala Arg Gly Ser
   1               5                  10                  15

 Asn Ala Cys Tyr Met Glu Glu Met Arg His Ile Asp Met Val Glu
                  20                  25                  30

 Gly Asp Glu Gly Arg Met Cys Ile Asn Met Glu Trp Gly Ala Phe
                  35                  40                  45

 Gly Asp Asp Gly Ser Leu Asn Asp Ile Arg Thr Glu Phe Asp Gln
                  50                  55                  60

 Glu Ile Asp Met Gly Ser Leu Asn Pro Gly Lys Gln Leu Phe Glu
                  65                  70                  75

 Lys Met Ile Ser Gly Met Tyr Met Gly Glu Leu Val Arg Leu Ile
                  80                  85                  90

 Leu Val Lys Met Ala Lys Glu Glu Leu Leu Phe Gly Gly Lys Leu
                  95                 100                 105

 Ser Pro Glu Leu Leu Asn Thr Gly Arg Phe Glu Thr Lys Asp Ile
                 110                 115                 120

 Ser Asp Ile Glu Gly Glu Lys Asp Gly Ile Arg Lys Ala Arg Glu
                 125                 130                 135

 Val Leu Met Arg Leu Gly Leu Asp Pro Thr Gln Glu Asp Cys Val
                 140                 145                 150

 Ala Thr His Arg Ile Cys Gln Ile Val Ser Thr Arg Ser Ala Ser
                 155                 160                 165

 Leu Cys Ala Ala Thr Leu Ala Ala Val Leu Gln Arg Ile Lys Glu
                 170                 175                 180

 Asn Lys Gly Glu Glu Arg Leu Arg Ser Thr Ile Gly Val Asp Gly
                 185                 190                 195

 Ser Val Tyr Lys Lys His Pro His Phe Ala Lys Arg Leu His Lys
                 200                 205                 210

 Thr Val Arg Arg Leu Val Pro Gly Cys Asp Val Arg Phe Leu Arg
                 215                 220                 225

 Ser Glu Asp Gly Ser Gly Lys Gly Ala Ala Met Val Thr Ala Val
                 230                 235                 240

 Ala Tyr Arg Leu Ala Asp Gln His Arg Ala Arg Gln Lys Thr Leu
                 245                 250                 255

 Glu His Leu Gln Leu Ser His Asp Gln Leu Leu Glu Val Lys Arg
                 260                 265                 270

 Arg Met Lys Val Glu Met Glu Arg Gly Leu Ser Lys Glu Thr His
                 275                 280                 285

 Ala Ser Ala Pro Val Lys Met Leu Pro Thr Tyr Val Cys Ala Thr
                 290                 295                 300

 Pro Asp Gly Thr Glu Lys Gly Asp Phe Leu Ala Leu Asp Leu Gly
                 305                 310                 315

 Gly Thr Asn Phe Arg Val Leu Leu Val Arg Val Arg Asn Gly Lys
                 320                 325                 330

 Trp Gly Gly Val Glu Met His Asn Lys Ile Tyr Ala Ile Pro Gln
                 335                 340                 345

 Glu Val Met His Gly Thr Gly Asp Glu Leu Phe Asp His Ile Val
                 350                 355                 360

 Gln Cys Ile Ala Asp Phe Leu Glu Tyr Met Gly Met Lys Gly Val
                 365                 370                 375

 Ser Leu Pro Leu Gly Phe Thr Phe Ser Phe Pro Cys Gln Gln Asn
                 380                 385                 390

 Ser Leu Asp Glu Ser Ile Leu Leu Lys Trp Thr Lys Gly Phe Lys
                 395                 400                 405

 Ala Ser Gly Cys Glu Gly Glu Asp Val Val Thr Leu Leu Lys Glu
                 410                 415                 420

 Ala Ile His Arg Arg Glu Glu Phe Asp Leu Asp Val Val Ala Val
                 425                 430                 435

 Val Asn Asp Thr Val Gly Thr Met Met Thr Cys Gly Phe Glu Asp
                 440                 445                 450

 Pro His Cys Glu Val Gly Leu Ile Val Gly Thr Gly Ser Asn Ala
                 455                 460                 465

 Cys Tyr Met Glu Glu Met Arg Asn Val Glu Leu Val Glu Gly Glu
                 470                 475                 480

 Glu Gly Arg Met Cys Val Asn Met Glu Trp Gly Ala Phe Gly Asp
                 485                 490                 495

 Asn Gly Cys Leu Asp Asp Phe Arg Thr Glu Phe Asp Val Ala Val
                 500                 505                 510

 Asp Glu Leu Ser Leu Asn Pro Gly Lys Gln Arg Phe Glu Lys Met
                 515                 520                 525

 Ile Ser Gly Met Tyr Leu Gly Glu Ile Val Arg Asn Ile Leu Ile
                 530                 535                 540

 Asp Phe Thr Lys Arg Gly Leu Leu Phe Arg Gly Arg Ile Ser Glu
                 545                 550                 555

 Arg Leu Lys Thr Arg Gly Ile Phe Glu Thr Lys Phe Leu Ser Gln
                 560                 565                 570

 Ile Glu Ser Asp Cys Leu Ala Leu Leu Gln Val Arg Ala Ile Leu
                 575                 580                 585

 Gln His Leu Gly Leu Glu Ser Thr Cys Asp Asp Ser Ile Ile Val
                 590                 595                 600

 Lys Glu Val Cys Thr Val Val Ala Arg Arg Ala Ala Gln Leu Cys
                 605                 610                 615

 Gly Ala Gly Met Ala Ala Val Val Asp Arg Ile Arg Glu Asn Arg
                 620                 625                 630

 Gly Leu Asp Ala Leu Lys Val Thr Val Gly Val Asp Gly Thr Leu
                 635                 640                 645

 Tyr Lys Leu His Pro His Phe Ala Lys Val Met His Glu Thr Val
                 650                 655                 660

 Lys Asp Leu Ala Pro Lys Cys Asp Val Ser Phe Leu Gln Ser Glu
                 665                 670                 675

 Asp Gly Ser Gly Lys Gly Ala Ala Leu Ile Thr Ala Val Ala Cys
                 680                 685                 690

 Arg Ile Arg Glu Ala Gly Gln Arg
                 695

<210> 761
<211> 1191
<212> DNA
<213> Homo sapien

<400> 761
 atggtggcgc gcaggaggaa gtgcgccgcg cgggacccgg aggaccgtat 50

 ccccagccca ctgggctacg cagctattcc aatcaagttc tctgaaaagc 100

 aacaggcttc tcactacctc tatgtgagag cacacggcgt tcgacaaggc 150

 accaagtcca cctggcctca gaagaggact ctttttgtcc tcaatgtgcc 200

 cccatactgc acagaggaga gcctgtcccg cctcctgtcc acctgtggcc 250

 tcgtccagtc tgtagagttg caggagaagc cggacctggc tgagagccca 300

 aaggagtcaa ggtcgaagtt ttttcatccc aagccagttc cgggtttcca 350

 ggtagcctat gtggtgttcc agaagccaag tggggtgtca gcggccttgg 400

 ccctgaaggg ccccctgctg gtgtccacag agagccaccc tgtgaagagt 450

 ggcattcaca agtggatcag tgactacgca gactctgtgc ccgaccctga 500

 ggccctgagg gtggaagtgg acacgttcat ggaggcatat gaccagaaga 550

 tcgctgagga agaagctaag gccaaggagg aggagggggt ccctgacgag 600

 gagggctggg tgaaggtgac ccgccggggc cggcggcctg tgctcccccg 650

 gactgaggca gccagcttgc gggtgctgga gagggagaga cggaagcgca 700

 gccgaaaaga gctgctcaac ttctacgcct ggcagcatcg agagagcaag 750

 atggagcatc tagcgcagct gcgcaagaag ttcgaggagg acaagcagag 800

 gatcgagctg ctgcgggccc agcgcaaatt ccgaccgtac tgagctgtga 850

 gagccgcagt gaatggctgg aggtgcaggg ccaggaggag gcgaggcagg 900

 gcctgcagcg gtctctgaga ggccgagctc tggccaacgg gccccaggtt 950

 gaaggccacc gcgtccaaca gccccatcag agtccacaca ggccaggagg 1000

 gaaggaccag gccacccctc gggtcttgtg cttcagcagt cctggggacc 1050

 caggcgtgcc gagaggagga cttgtccttc ctgcttcttg cctccacacc 1100

 ctcctctcca ggaccctgga tgaatccgtt ctgtgcttcc ttttccctca 1150

 atgcaaaagc ccttgctggc aacgaaaaag cctcaaaagc a 1191

<210> 762
<211> 280
<212> PRT
<213> Homo sapien

<400> 762
 Met Val Ala Arg Arg Arg Lys Cys Ala Ala Arg Asp Pro Glu Asp
   1               5                  10                  15

 Arg Ile Pro Ser Pro Leu Gly Tyr Ala Ala Ile Pro Ile Lys Phe
                  20                  25                  30

 Ser Glu Lys Gln Gln Ala Ser His Tyr Leu Tyr Val Arg Ala His
                  35                  40                  45

 Gly Val Arg Gln Gly Thr Lys Ser Thr Trp Pro Gln Lys Arg Thr
                  50                  55                  60

 Leu Phe Val Leu Asn Val Pro Pro Tyr Cys Thr Glu Glu Ser Leu
                  65                  70                  75

 Ser Arg Leu Leu Ser Thr Cys Gly Leu Val Gln Ser Val Glu Leu
                  80                  85                  90

 Gln Glu Lys Pro Asp Leu Ala Glu Ser Pro Lys Glu Ser Arg Ser
                  95                 100                 105

 Lys Phe Phe His Pro Lys Pro Val Pro Gly Phe Gln Val Ala Tyr
                 110                 115                 120

 Val Val Phe Gln Lys Pro Ser Gly Val Ser Ala Ala Leu Ala Leu
                 125                 130                 135

 Lys Gly Pro Leu Leu Val Ser Thr Glu Ser His Pro Val Lys Ser
                 140                 145                 150

 Gly Ile His Lys Trp Ile Ser Asp Tyr Ala Asp Ser Val Pro Asp
                 155                 160                 165

 Pro Glu Ala Leu Arg Val Glu Val Asp Thr Phe Met Glu Ala Tyr
                 170                 175                 180

 Asp Gln Lys Ile Ala Glu Glu Glu Ala Lys Ala Lys Glu Glu Glu
                 185                 190                 195

 Gly Val Pro Asp Glu Glu Gly Trp Val Lys Val Thr Arg Arg Gly
                 200                 205                 210

 Arg Arg Pro Val Leu Pro Arg Thr Glu Ala Ala Ser Leu Arg Val
                 215                 220                 225

 Leu Glu Arg Glu Arg Arg Lys Arg Ser Arg Lys Glu Leu Leu Asn
                 230                 235                 240

 Phe Tyr Ala Trp Gln His Arg Glu Ser Lys Met Glu His Leu Ala
                 245                 250                 255

 Gln Leu Arg Lys Lys Phe Glu Glu Asp Lys Gln Arg Ile Glu Leu
                 260                 265                 270

 Leu Arg Ala Gln Arg Lys Phe Arg Pro Tyr
                 275                 280

<210> 763
<211> 827
<212> DNA
<213> Homo sapien

<400> 763
 ggaacagtgt ggcccgccat gttcttctcc gcggcgctcc gggcccgggc 50

 ggctggcctc accgcccact ggggaagaca tgtaaggaat ttgcataaga 100

 cagctatgca aaatggagct ggaggagctt tatttgtgca cagagatact 150

 cctgagaata accctgatac tccatttgat ttcacaccag aaaactataa 200

 gaggatagag gcaattgtaa aaaactatcc agaaggccat aaagcagcag 250

 ctgttcttcc agtcctggat ttagcccaaa ggcagaatgg gtggttgccc 300

 atctctgcta tgaacaaggt tgcagaagtt ttacaagtac ctccaatgag 350

 agtatatgaa gtagcaactt tttatacaat gtataatcga aagccagttg 400

 gaaagtatca cattcaggtc tgcactacta caccctgcat gcttcgaaac 450

 tctgacagca tactggaggc cattcagaaa aagcttggaa taaaggttgg 500

 ggagactaca cctgacaaac ttttcactct tatagaagtg gaatgtttag 550

 gggcctgtgt gaacgcacca atggttcaaa taaatgacaa ttactatgag 600

 gatttgacag ctaaggatat tgaagaaatt attgatgagc tcaaggctgg 650

 caaaatccca aaaccagggc caaggagtgg acgcttctct tgtgagccag 700

 ctggaggtct tacctctttg actgaaccac ccaagggacc tggatttggt 750

 gtacaagcag gcctttaatt tatattgaac tgtaaatatg tcactagaga 800

 aataaaatat ggacttccaa tctacgt 827

<210> 764
<211> 249
<212> PRT
<213> Homo sapien

<400> 764
 Met Phe Phe Ser Ala Ala Leu Arg Ala Arg Ala Ala Gly Leu Thr
   1               5                  10                  15

 Ala His Trp Gly Arg His Val Arg Asn Leu His Lys Thr Ala Met
                  20                  25                  30

 Gln Asn Gly Ala Gly Gly Ala Leu Phe Val His Arg Asp Thr Pro
                  35                  40                  45

 Glu Asn Asn Pro Asp Thr Pro Phe Asp Phe Thr Pro Glu Asn Tyr
                  50                  55                  60

 Lys Arg Ile Glu Ala Ile Val Lys Asn Tyr Pro Glu Gly His Lys
                  65                  70                  75

 Ala Ala Ala Val Leu Pro Val Leu Asp Leu Ala Gln Arg Gln Asn
                  80                  85                  90

 Gly Trp Leu Pro Ile Ser Ala Met Asn Lys Val Ala Glu Val Leu
                  95                 100                 105

 Gln Val Pro Pro Met Arg Val Tyr Glu Val Ala Thr Phe Tyr Thr
                 110                 115                 120

 Met Tyr Asn Arg Lys Pro Val Gly Lys Tyr His Ile Gln Val Cys
                 125                 130                 135

 Thr Thr Thr Pro Cys Met Leu Arg Asn Ser Asp Ser Ile Leu Glu
                 140                 145                 150

 Ala Ile Gln Lys Lys Leu Gly Ile Lys Val Gly Glu Thr Thr Pro
                 155                 160                 165

 Asp Lys Leu Phe Thr Leu Ile Glu Val Glu Cys Leu Gly Ala Cys
                 170                 175                 180

 Val Asn Ala Pro Met Val Gln Ile Asn Asp Asn Tyr Tyr Glu Asp
                 185                 190                 195

 Leu Thr Ala Lys Asp Ile Glu Glu Ile Ile Asp Glu Leu Lys Ala
                 200                 205                 210

 Gly Lys Ile Pro Lys Pro Gly Pro Arg Ser Gly Arg Phe Ser Cys
                 215                 220                 225

 Glu Pro Ala Gly Gly Leu Thr Ser Leu Thr Glu Pro Pro Lys Gly
                 230                 235                 240

 Pro Gly Phe Gly Val Gln Ala Gly Leu
                 245

<210> 765
<211> 852
<212> DNA
<213> Homo sapien

<400> 765
 caccctgtaa gtggctgcgg cgggaagatg gcggagctgc gcgtgctcgt 50

 agctgtcaag agggtcatcg actacgccgt gaagatccga gtgaagcctg 100

 acaggaccgg tgtggtcacg gatggtgtga agcactccat gaaccccttc 150

 tgtgagatcg cggtggagga ggctgtgcgg ctcaaggaga agaagctggt 200

 gaaggaggtc atcgccgtca gctgtgggcc tgcacagtgc caggagacga 250

 ttcgtaccgc cctggccatg ggtgcagacc gaggtatcca cgtggaggtg 300

 cccccagcag aagcagaacg cttgggtccc ctgcaggtgg ctcgggtcct 350

 ggccaagctg gcagagaagg agaaggtgga cctggtgctg ctgggcaaac 400

 aggccatcga tgatgactgt aaccagacag ggcagatgac agctggattt 450

 cttgactggc cacagggcac attcgcctcc caggtgacgc tggaggggga 500

 caagttgaaa gtggagcggg agatcgatgg gggcctggag accctgcgcc 550

 tgaagctgcc agctgtggtg acagctgacc tgaggctcaa cgagccccgc 600

 tacgccacgc tgcccaacat catgaaagcc aagaagaaga agatcgaggt 650

 gatcaagcct ggggacctgg gtgtggacct gacctccaag ctctctgtga 700

 tcagtgtgga ggacccgccc cagcgcacgg ccggcgtcaa ggtggagacc 750

 actgaggacc tggtggccaa gctgaaggag attgggcgga tttgagcccc 800

 tcccagagat ggcaataaaa ctgactctca acatcaaaaa aaaaaaaaaa 850

 aa 852

<210> 766
<211> 255
<212> PRT
<213> Homo sapien

<400> 766
 Met Ala Glu Leu Arg Val Leu Val Ala Val Lys Arg Val Ile Asp
   1               5                  10                  15

 Tyr Ala Val Lys Ile Arg Val Lys Pro Asp Arg Thr Gly Val Val
                  20                  25                  30

 Thr Asp Gly Val Lys His Ser Met Asn Pro Phe Cys Glu Ile Ala
                  35                  40                  45

 Val Glu Glu Ala Val Arg Leu Lys Glu Lys Lys Leu Val Lys Glu
                  50                  55                  60

 Val Ile Ala Val Ser Cys Gly Pro Ala Gln Cys Gln Glu Thr Ile
                  65                  70                  75

 Arg Thr Ala Leu Ala Met Gly Ala Asp Arg Gly Ile His Val Glu
                  80                  85                  90

 Val Pro Pro Ala Glu Ala Glu Arg Leu Gly Pro Leu Gln Val Ala
                  95                 100                 105

 Arg Val Leu Ala Lys Leu Ala Glu Lys Glu Lys Val Asp Leu Val
                 110                 115                 120

 Leu Leu Gly Lys Gln Ala Ile Asp Asp Asp Cys Asn Gln Thr Gly
                 125                 130                 135

 Gln Met Thr Ala Gly Phe Leu Asp Trp Pro Gln Gly Thr Phe Ala
                 140                 145                 150

 Ser Gln Val Thr Leu Glu Gly Asp Lys Leu Lys Val Glu Arg Glu
                 155                 160                 165

 Ile Asp Gly Gly Leu Glu Thr Leu Arg Leu Lys Leu Pro Ala Val
                 170                 175                 180

 Val Thr Ala Asp Leu Arg Leu Asn Glu Pro Arg Tyr Ala Thr Leu
                 185                 190                 195

 Pro Asn Ile Met Lys Ala Lys Lys Lys Lys Ile Glu Val Ile Lys
                 200                 205                 210

 Pro Gly Asp Leu Gly Val Asp Leu Thr Ser Lys Leu Ser Val Ile
                 215                 220                 225

 Ser Val Glu Asp Pro Pro Gln Arg Thr Ala Gly Val Lys Val Glu
                 230                 235                 240

 Thr Thr Glu Asp Leu Val Ala Lys Leu Lys Glu Ile Gly Arg Ile
                 245                 250                 255

<210> 767
<211> 783
<212> DNA
<213> Homo sapien

<400> 767
 ggcacgagcg agttcctgtc tctctgccaa cgccgcccgg atggcttccc 50

 aaaaccgcga cccagccgcc actagcgtcg ccgccgcccg taaaggagct 100

 gagccgagcg ggggcgccgc ccggggtccg gtgggcaaaa ggctacagca 150

 ggagctgatg accctcatga tgtctggcga taaagggatt tctgccttcc 200

 ctgaatcaga caaccttttc aaatgggtag ggaccatcca tggagcagct 250

 ggaacagtat atgaagacct gaggtataag ctctcgctag agttccccag 300

 tggctaccct tacaatgcgc ccacagtgaa gttcctcacg ccctgctatc 350

 accccaacgt ggacacccag ggtaacatat gcctggacat cctgaaggaa 400

 aagtggtctg ccctgtatga tgtcaggacc attctgctct ccatccagag 450

 ccttctagga gaacccaaca ttgatagtcc cttgaacaca catgctgccg 500

 agctctggaa aaaccccaca gcttttaaga agtacctgca agaaacctac 550

 tcaaagcagg tcaccagcca ggagccctga cccaggctgc ccagcctgtc 600

 cttgtgtcgt ctttttaatt tttccttaga tggtctgtcc tttttgtgat 650

 ttctgtatag gactctttat cttgagctgt ggtatttttg ttttgttttt 700

 gtcttttaaa ttaagcctcg gttgagccct tgtatattaa ataaatgcat 750

 ttttgtcctt ttttaaaaaa aaaaaaaaaa aaa 783

<210> 768
<211> 179
<212> PRT
<213> Homo sapien

<400> 768
 Met Ala Ser Gln Asn Arg Asp Pro Ala Ala Thr Ser Val Ala Ala
   1               5                  10                  15

 Ala Arg Lys Gly Ala Glu Pro Ser Gly Gly Ala Ala Arg Gly Pro
                  20                  25                  30

 Val Gly Lys Arg Leu Gln Gln Glu Leu Met Thr Leu Met Met Ser
                  35                  40                  45

 Gly Asp Lys Gly Ile Ser Ala Phe Pro Glu Ser Asp Asn Leu Phe
                  50                  55                  60

 Lys Trp Val Gly Thr Ile His Gly Ala Ala Gly Thr Val Tyr Glu
                  65                  70                  75

 Asp Leu Arg Tyr Lys Leu Ser Leu Glu Phe Pro Ser Gly Tyr Pro
                  80                  85                  90

 Tyr Asn Ala Pro Thr Val Lys Phe Leu Thr Pro Cys Tyr His Pro
                  95                 100                 105

 Asn Val Asp Thr Gln Gly Asn Ile Cys Leu Asp Ile Leu Lys Glu
                 110                 115                 120

 Lys Trp Ser Ala Leu Tyr Asp Val Arg Thr Ile Leu Leu Ser Ile
                 125                 130                 135

 Gln Ser Leu Leu Gly Glu Pro Asn Ile Asp Ser Pro Leu Asn Thr
                 140                 145                 150

 His Ala Ala Glu Leu Trp Lys Asn Pro Thr Ala Phe Lys Lys Tyr
                 155                 160                 165

 Leu Gln Glu Thr Tyr Ser Lys Gln Val Thr Ser Gln Glu Pro
                 170                 175

<210> 769
<211> 1227
<212> DNA
<213> Homo sapien

<400> 769
 gggagttaga caaaatgcca ggaatgttct tctctgctaa cccaaaggaa 50

 ttgaaaggaa ccactcattc acttctagac gacaaaatgc aaaaaaggag 100

 gccaaagact tttggaatgg atatgaaagc atacctgaga tctatgatcc 150

 cacatctgga atctggaatg aaatcttcca agtccaagga tgtactttct 200

 gctgctgaag taatgcaatg gtctcaatct ctggaaaaac ttcttgccaa 250

 ccaaactggt caaaatgtct ttggaagttt cctaaagtct gaattcagtg 300

 aggagaatat tgagttctgg ctggcttgtg aagactataa gaaaacagag 350

 tctgatcttt tgccctgtaa agcagaagag atatataaag catttgtgca 400

 ttcagatgct gctaaacaaa tcaatattga cttccgcact cgagaatcta 450

 cagccaagaa gattaaagca ccaaccccca cgtgttttga tgaagcacaa 500

 aaagtcatat atactcttat ggaaaaggac tcttatccca ggttcctcaa 550

 atcacatatt tacttaaatc ttctaaatga cctgcaggct aatagcctaa 600

 agtgactggt ccctggctga agggaattaa cagatagtat cagcgcagaa 650

 ggaatgtgcc agtatggatc cctgggtgaa cagcttggcc ttttttgggt 700

 gtcttgacag gccaagaaga acaaatgact cagaaccgga ttaacatgaa 750

 agttatccag gcgcagagtt gaagaagcat aagcaagcaa gacaaaaaca 800

 gagagaccgc aaggaggaag atctgtggta ctgtcataaa aaacagtgga 850

 gctctgtatt agaaaagccc ctcagaactg ggaaggccag gtaactctag 900

 ttacacagaa actggtacta aagtctatca aactgattac acagactgta 950

 agaattcaaa gtcaactgac atctatgcta catatattat atagtttgta 1000

 cttgactatg agccattaac ttaaagcata tgtttcaaat agccattgct 1050

 actattcctt gtccggtgta attttatttt attgttttta ctttggaaga 1100

 gatgaactgt gtatttaact taagctattg ctcttaaaac cagggagtca 1150

 gatatatttg taaggttaaa tcattggtgc aataataaat gtggattttg 1200

 tattaaaata tatatgaagc aaaaaaa 1227

<210> 770
<211> 196
<212> PRT
<213> Homo sapien

<400> 770
 Met Pro Gly Met Phe Phe Ser Ala Asn Pro Lys Glu Leu Lys Gly
   1               5                  10                  15

 Thr Thr His Ser Leu Leu Asp Asp Lys Met Gln Lys Arg Arg Pro
                  20                  25                  30

 Lys Thr Phe Gly Met Asp Met Lys Ala Tyr Leu Arg Ser Met Ile
                  35                  40                  45

 Pro His Leu Glu Ser Gly Met Lys Ser Ser Lys Ser Lys Asp Val
                  50                  55                  60

 Leu Ser Ala Ala Glu Val Met Gln Trp Ser Gln Ser Leu Glu Lys
                  65                  70                  75

 Leu Leu Ala Asn Gln Thr Gly Gln Asn Val Phe Gly Ser Phe Leu
                  80                  85                  90

 Lys Ser Glu Phe Ser Glu Glu Asn Ile Glu Phe Trp Leu Ala Cys
                  95                 100                 105

 Glu Asp Tyr Lys Lys Thr Glu Ser Asp Leu Leu Pro Cys Lys Ala
                 110                 115                 120

 Glu Glu Ile Tyr Lys Ala Phe Val His Ser Asp Ala Ala Lys Gln
                 125                 130                 135

 Ile Asn Ile Asp Phe Arg Thr Arg Glu Ser Thr Ala Lys Lys Ile
                 140                 145                 150

 Lys Ala Pro Thr Pro Thr Cys Phe Asp Glu Ala Gln Lys Val Ile
                 155                 160                 165

 Tyr Thr Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Lys Ser
                 170                 175                 180

 His Ile Tyr Leu Asn Leu Leu Asn Asp Leu Gln Ala Asn Ser Leu
                 185                 190                 195

 Lys


<210> 771
<211> 1280
<212> DNA
<213> Homo sapien

<400> 771
 gcggccgccg tggccaggca acctatgggt accaccgggt tctcgcgggt 50

 cttgcgaacg aacttttcct tgaaactctc tggattcctg taaacagtgg 100

 ggctcagccc ctcaatgact ggaggcttcg atggttcaaa ggggacctcc 150

 ggaatcacag ggccgggagt cgccatgtcc gggccacagc agcaggagaa 200

 aatcgggact ccgacctcag cctcccggtg aaggtcatga aaggggcggg 250

 gaaacgaata aattgagcct tgtacgcagg cgcaaatgct cgttgcatcc 300

 tgggagtcgt agtgctcagc acggtagtgc tacaaaagga ctacatttcc 350

 ccaaatgccc gcaaagcctt gtgcacgcct tccggaagga gtttgttaca 400

 cgaggtctga gagacagagg cagcgtgttt gagctgctgg tgcggtggtc 450

 agcgcgatgc ccaaggccaa gggcaaaacc cggaggcaga agtttggtta 500

 cagtgtcaac cgaaagcgtc tgaaccggaa tgctcgacgg aaggcagcgc 550

 gcggaatcga atgctcccac atccgacatg cctgggacca cgctaaatcg 600

 gtacggcaga acctggccga gatggggttg gctgtggacc ccaacagggc 650

 ggtgcccctc cgtaagagaa aggtgaaggc catggaggtg gacatagagg 700

 agaggcctaa agagcttgta cggaagccct atgtgctgaa tgacctggag 750

 gcagaagcca gccttccaga aaagaaagga aatactctgt ctcgggacct 800

 cattgactat gtacgctaca tggtagagaa ccacggggag gactataagg 850

 ccatggcccg tgatgagaag aattactatc aagatacccc aaaacagatt 900

 cggagtaaga tcaacgtcta taaacgcttt tacccagcag agtggcaaga 950

 cttcctcgat tctttgcaga agaggaagat ggaggtggag taactggttt 1000

 acatcacagc tgccccaggc tgaggcgtcc cccggaccag tgaagctgga 1050

 gccagggtgt aaggcaagga ggtgctgtgt ggctccagag gggctggcca 1100

 ggtcccatgg aatcagaagg ttacacacac acgtgcacac tccccgctct 1150

 ggggaaggaa ctgttctcag aggctccaat ttatattcat ctgggggttc 1200

 acggaaaagc cagaacctgc tgttttcagg gtgggtgatg taaatatagt 1250

 gtgtacataa taaagcaaat atattttaaa 1280

<210> 772
<211> 178
<212> PRT
<213> Homo sapien

<400> 772
 Met Pro Lys Ala Lys Gly Lys Thr Arg Arg Gln Lys Phe Gly Tyr
   1               5                  10                  15

 Ser Val Asn Arg Lys Arg Leu Asn Arg Asn Ala Arg Arg Lys Ala
                  20                  25                  30

 Ala Arg Gly Ile Glu Cys Ser His Ile Arg His Ala Trp Asp His
                  35                  40                  45

 Ala Lys Ser Val Arg Gln Asn Leu Ala Glu Met Gly Leu Ala Val
                  50                  55                  60

 Asp Pro Asn Arg Ala Val Pro Leu Arg Lys Arg Lys Val Lys Ala
                  65                  70                  75

 Met Glu Val Asp Ile Glu Glu Arg Pro Lys Glu Leu Val Arg Lys
                  80                  85                  90

 Pro Tyr Val Leu Asn Asp Leu Glu Ala Glu Ala Ser Leu Pro Glu
                  95                 100                 105

 Lys Lys Gly Asn Thr Leu Ser Arg Asp Leu Ile Asp Tyr Val Arg
                 110                 115                 120

 Tyr Met Val Glu Asn His Gly Glu Asp Tyr Lys Ala Met Ala Arg
                 125                 130                 135

 Asp Glu Lys Asn Tyr Tyr Gln Asp Thr Pro Lys Gln Ile Arg Ser
                 140                 145                 150

 Lys Ile Asn Val Tyr Lys Arg Phe Tyr Pro Ala Glu Trp Gln Asp
                 155                 160                 165

 Phe Leu Asp Ser Leu Gln Lys Arg Lys Met Glu Val Glu
                 170                 175

<210> 773
<211> 687
<212> DNA
<213> Homo sapien

<400> 773
 gcagtgtccc agccgggttc gtgtcgccat ggggcagatc gagtgggcca 50

 tgtgggccaa cgagcaggcg ctggcgtccg gcctgatcct catcaccggg 100

 ggcatcgtgg ccacagctgg gcgcttcacc cagtggtact ttggtgccta 150

 ctccattgtg gcgggcgtgt ttgtgtgcct gctggagtac ccccggggga 200

 agaggaagaa gggctccacc atggagcgct ggggacagaa gcacatgacc 250

 gccgtggtga agctgttcgg gccctttacc aggaattact atgttcgggc 300

 cgtcctgcat ctcctgctct cggtgcccgc cggcttcctg ctggccacca 350

 tccttgggac cgcctgcctg gccattgcga gcggcatcta cctactggcg 400

 gctgtgcgtg gcgagcagtg gacgcccatc gagcccaagc cccgggagcg 450

 gccgcagatc ggaggcacca tcaagcagcc gcccagcaac cccccgccgc 500

 ggcccccggc cgaggcccgc aagaagccca gcgaggagga ggctgcggcg 550

 gcggcggggg gacccccggg aggtccccag gtcaacccca tcccggtgac 600

 cgacgaggtc gtgtgacctc gccccggacc tgccctccca ccaggtgcac 650

 ccacctgcaa taaacgcagc gaaggccggg aaaaaaa 687

<210> 774
<211> 195
<212> PRT
<213> Homo sapien

<400> 774
 Met Gly Gln Ile Glu Trp Ala Met Trp Ala Asn Glu Gln Ala Leu
   1               5                  10                  15

 Ala Ser Gly Leu Ile Leu Ile Thr Gly Gly Ile Val Ala Thr Ala
                  20                  25                  30

 Gly Arg Phe Thr Gln Trp Tyr Phe Gly Ala Tyr Ser Ile Val Ala
                  35                  40                  45

 Gly Val Phe Val Cys Leu Leu Glu Tyr Pro Arg Gly Lys Arg Lys
                  50                  55                  60

 Lys Gly Ser Thr Met Glu Arg Trp Gly Gln Lys His Met Thr Ala
                  65                  70                  75

 Val Val Lys Leu Phe Gly Pro Phe Thr Arg Asn Tyr Tyr Val Arg
                  80                  85                  90

 Ala Val Leu His Leu Leu Leu Ser Val Pro Ala Gly Phe Leu Leu
                  95                 100                 105

 Ala Thr Ile Leu Gly Thr Ala Cys Leu Ala Ile Ala Ser Gly Ile
                 110                 115                 120

 Tyr Leu Leu Ala Ala Val Arg Gly Glu Gln Trp Thr Pro Ile Glu
                 125                 130                 135

 Pro Lys Pro Arg Glu Arg Pro Gln Ile Gly Gly Thr Ile Lys Gln
                 140                 145                 150

 Pro Pro Ser Asn Pro Pro Pro Arg Pro Pro Ala Glu Ala Arg Lys
                 155                 160                 165

 Lys Pro Ser Glu Glu Glu Ala Ala Ala Ala Ala Gly Gly Pro Pro
                 170                 175                 180

 Gly Gly Pro Gln Val Asn Pro Ile Pro Val Thr Asp Glu Val Val
                 185                 190                 195

<210> 775
<211> 4719
<212> DNA
<213> Homo sapien

<400> 775
 aaccggctgc ggggatgggg ccaccgctcc cgctgctgct gctgctactg 50

 ctgctgctgc cgccacgcgt cctgcctgcc gccccttcgt ccgtcccccg 100

 cggccggcag ctcccggggc gtctgggctg cctgctcgag gagggcctct 150

 gcggagcgtc cgaggcctgt gtgaacgatg gagtgtttgg aaggtgccag 200

 aaggttccgg caatggactt ttaccgctac gaggtgtcgc ccgtggccct 250

 gcagcgcctg cgcgtggcgt tgcagaagct ttccggcaca ggtttcacgt 300

 ggcaggatga ctatactcag tatgtgatgg accaggaact tgcagacctc 350

 ccgaaaacct acctgaggcg tcctgaagca tccagcccag ccaggccctc 400

 aaaacacagc gttggcagcg agaggaggta cagtcgggag ggcggtgctg 450

 ccctggccaa cgccctccga cgccacctgc ccttcctgga ggccctgtcc 500

 caggccccag cctcagacgt gctcgccagg acccatacgg cgcaggacag 550

 accccccgct gagggtgatg accgcttctc cgagagcatc ctgacctatg 600

 tggcccacac gtctgcgctg acgtaccctc ccgggccccg gacccagctc 650

 cgggaggacc tcctgccgcg gaccctcggc cagctccagc cagatgagct 700

 cagccctaag gtggacagtg gtgtggacag acaccatctg atggcggccc 750

 tcagtgccta tgctgcccag aggcccccag ctccccccgg ggagggcagc 800

 ctggagccac agtaccttct gcgtgcaccc tcaagaatgc ccaggccttt 850

 gctggcacca gccgcccccc agaagtggcc ttcacctctg ggagattccg 900

 aagacccctc cagcacaggc gatggagcac ggattcatac cctcctgaag 950

 gacctgcaga ggcagccggc tgaggtgagg ggcctgagtg gcctggagct 1000

 ggacggcatg gctgagctga tggctggcct gatgcaaggc gtggaccatg 1050

 gagtagctcg aggcagccct gggagagcgg ccctgggaga gtctggagaa 1100

 caggcggatg gccccaaggc caccctccgt ggagacagct ttccagatga 1150

 cggagtgcag gacgacgatg atagacttta ccaagaggtc caccgtctga 1200

 gtgccacact cgggggcctc ctgcaggacc acgggtctcg actcttacct 1250

 ggagccctcc cctttgcaag gcccctcgac atggagagga agaagtccga 1300

 gcaccctgag tcttccctgt cttcagaaga ggagactgcc ggagtggaga 1350

 acgtcaagag ccagacgtat tccaaagatc tgctggggca gcagccgcat 1400

 tcggagcccg gggccgctgc gtttggggag ctccaaaacc agatgcctgg 1450

 gccctcgaag gaggagcaga gccttccagc gggtgctcag gaggccctca 1500

 gcgacggcct gcaattggag gtccagcctt ccgaggaaga ggcgcggggc 1550

 tacatcgtga cagacagaga ccccctgcgc cccgaggaag gaaggcggct 1600

 ggtggaggac gtcgcccgcc tcctgcaggt gcccagcagt gcgttcgctg 1650

 acgtggaggt tctcggacca gcagtgacct tcaaagtgag cgccaatgtc 1700

 caaaacgtga ccactgagga tgtggagaag gccacagttg acaacaaaga 1750

 caaactggag gaaacctctg gactgaaaat tcttcaaacc ggagtcgggt 1800

 cgaaaagcaa actcaagttc ctgcctcctc aggcggagca agaagactcc 1850

 accaagttca tcgcgctcac cctggtctcc ctcgcctgca tcctgggcgt 1900

 cctcctggcc tctggcctca tctactgcct ccgccatagc tctcagcaca 1950

 ggctgaagga gaagctctcg ggactagggg gcgacccagg tgcagatgcc 2000

 actgccgcct accaggagct gtgccgccag cgtatggcca cgcggccacc 2050

 agaccgacct gagggcccgc acacgtcacg catcagcagc gtctcatccc 2100

 agttcagcga cgggccgatc cccagcccct ccgcacgcag cagcgcctca 2150

 tcctggtccg aggagcctgt gcagtccaac atggacatct ccaccggcca 2200

 catgatcctg tcctacatgg aggaccacct gaagaacaag aaccggctgg 2250

 agaaggagtg ggaagcgctg tgcgcctacc aggcggagcc caacagctcg 2300

 ttcgtggccc agagggagga gaacgtgccc aagaaccgct ccctggctgt 2350

 gctgacctat gaccactccc gggtcctgct gaaggcggag aacagccaca 2400

 gccactcaga ctacatcaac gctagcccca tcatggatca cgacccgagg 2450

 aaccccgcgt acatcgccac ccagggaccg ctgcccgcca ccgtggctga 2500

 cttttggcag atggtgtggg agagcggctg cgtggtgatc gtcatgctga 2550

 cacccctcgc ggagaacggc gtccggcagt gctaccacta ctggccggat 2600

 gaaggctcca atctctacca catctatgag gtgaacctgg tctccgagca 2650

 catctggtgt gaggacttcc tggtgaggag cttctatctg aagaacctgc 2700

 agaccaacga gacgcgcacc gtgacgcagt tccacttcct gagttggtat 2750

 gaccgaggag tcccttcctc ctcaaggtcc ctcctggact tccgcagaaa 2800

 agtaaacaaa tgctacaggg gccgttcttg tccgataatt gttcattgca 2850

 gtgacggtgc aggccggagc ggcacctacg tcctgatcga catggttctc 2900

 aacaagatgg ccaaaggtgc taaagagatt gatatcgcag cgaccctgga 2950

 gcacttgagg gaccagagac ccggcatggt ccagacgaag gagcagtttg 3000

 agttcgcgct gacagccgtg gctgaggagg tgaacgccat cctcaaggcc 3050

 cttccccagt gagcggcagc gtcaggggcc tcaggggagc ccccacccca 3100

 cggatgttgt caggaatcat gatctgactt taattgtgtg tcttctatta 3150

 taactgcata gtaatagggc ccttagctct cccgtagtca gcgcagttta 3200

 gcagttaaaa gtgtattttt gtttaatcaa acaataataa agagagattt 3250

 gtggaaaaat ccagttacgg gtggagggga atcggttcat caattttcac 3300

 ttgcttaaaa aaaatacttt ttcttaaagc acccgttcac cttcttggtt 3350

 gaagttgtgt taacaatgca gtagccagca cgttcgaggc ggtttccagg 3400

 aagagtgtgc ttgtcatctg ccactttcgg gagggtggat ccactgtgca 3450

 ggagtggccg gggaagctgg cagcactcag tgaggccgcc cggcacacaa 3500

 ggcacgtttg gcatttctct ttgagagagt ttatcattgg gagaagccgc 3550

 ggggacagaa ctgaacgtcc tgcagcttcg gggcaagtga gacaatcaca 3600

 gctcctcgct gcgtctccat caacactgcg ccgggtacca tggacggccc 3650

 cgtcagccac accggtcagc ccaagcagag tgattcaggg gctccccggg 3700

 ggcagacacc tgtgcacccc atgagtagtg cccacttgag gctggcactc 3750

 ccctgacctc acctttgcaa agttacagat gcaccccaac attgagatgt 3800

 gtttttaatg ttaaaatatt gatttctacg ttatgaaaac agatgccccc 3850

 gtgaatgctt acctgtgaga taaccacaac caggaagaac aaatctgggc 3900

 attgagcaag ctatgagggt ccccgggagc acacgaaccc tgccaggccc 3950

 ccgctggctc ctccaggcac gtcccggacc tgtggggccc cagagagggg 4000

 acatttccct cctgggagag aaggagatca gggcaactcg gagagggctg 4050

 cgagcatttc cctcccggga gaggaaatca gggcgacctg cacgcactgc 4100

 gtagagcctg gaagggaagt gagaaaccag ccgaccggcc ctgcccctct 4150

 tcccgggatc acttaatgaa ccacgtgttt tgacatcatg ttaacctaag 4200

 cacgtacaga tgattccgga tttgacaaaa taacatttga gtatccgatt 4250

 cgccatcacc cctacccccg aaataggaca actcacttca ttgaccagga 4300

 tgatcacatg gaaggcggcg cagaggcagc tgtgtgggct gcagatttcc 4350

 tgtgtggggt tcagcgtata aaacgcacct ccatcccgcc cttcccacag 4400

 cattcctcca tcttagatag atggtactct ccaaaggccc taccagaggg 4450

 aacacggcct actgagcgga cagaatgatg ccaaaatatt gcttatgtct 4500

 ctacatggta ttgtaatgaa tatctgcttt aatatagcta tcatttcttt 4550

 tccaaaatta cttctcttta tctggaattt aattaatcga aatgaattta 4600

 tctgaatata ggaagcatat gcctacttgt aatttctaac tacttatgtt 4650

 tgaagagaaa cctccggtgt gagatataca aatatattta attgtgtcat 4700

 attaaacttc ccggaattc 4719

<210> 776
<211> 1015
<212> PRT
<213> Homo sapien

<400> 776
 Met Gly Pro Pro Leu Pro Leu Leu Leu Leu Leu Leu Leu Leu Leu
   1               5                  10                  15

 Pro Pro Arg Val Leu Pro Ala Ala Pro Ser Ser Val Pro Arg Gly
                  20                  25                  30

 Arg Gln Leu Pro Gly Arg Leu Gly Cys Leu Leu Glu Glu Gly Leu
                  35                  40                  45

 Cys Gly Ala Ser Glu Ala Cys Val Asn Asp Gly Val Phe Gly Arg
                  50                  55                  60

 Cys Gln Lys Val Pro Ala Met Asp Phe Tyr Arg Tyr Glu Val Ser
                  65                  70                  75

 Pro Val Ala Leu Gln Arg Leu Arg Val Ala Leu Gln Lys Leu Ser
                  80                  85                  90

 Gly Thr Gly Phe Thr Trp Gln Asp Asp Tyr Thr Gln Tyr Val Met
                  95                 100                 105

 Asp Gln Glu Leu Ala Asp Leu Pro Lys Thr Tyr Leu Arg Arg Pro
                 110                 115                 120

 Glu Ala Ser Ser Pro Ala Arg Pro Ser Lys His Ser Val Gly Ser
                 125                 130                 135

 Glu Arg Arg Tyr Ser Arg Glu Gly Gly Ala Ala Leu Ala Asn Ala
                 140                 145                 150

 Leu Arg Arg His Leu Pro Phe Leu Glu Ala Leu Ser Gln Ala Pro
                 155                 160                 165

 Ala Ser Asp Val Leu Ala Arg Thr His Thr Ala Gln Asp Arg Pro
                 170                 175                 180

 Pro Ala Glu Gly Asp Asp Arg Phe Ser Glu Ser Ile Leu Thr Tyr
                 185                 190                 195

 Val Ala His Thr Ser Ala Leu Thr Tyr Pro Pro Gly Pro Arg Thr
                 200                 205                 210

 Gln Leu Arg Glu Asp Leu Leu Pro Arg Thr Leu Gly Gln Leu Gln
                 215                 220                 225

 Pro Asp Glu Leu Ser Pro Lys Val Asp Ser Gly Val Asp Arg His
                 230                 235                 240

 His Leu Met Ala Ala Leu Ser Ala Tyr Ala Ala Gln Arg Pro Pro
                 245                 250                 255

 Ala Pro Pro Gly Glu Gly Ser Leu Glu Pro Gln Tyr Leu Leu Arg
                 260                 265                 270

 Ala Pro Ser Arg Met Pro Arg Pro Leu Leu Ala Pro Ala Ala Pro
                 275                 280                 285

 Gln Lys Trp Pro Ser Pro Leu Gly Asp Ser Glu Asp Pro Ser Ser
                 290                 295                 300

 Thr Gly Asp Gly Ala Arg Ile His Thr Leu Leu Lys Asp Leu Gln
                 305                 310                 315

 Arg Gln Pro Ala Glu Val Arg Gly Leu Ser Gly Leu Glu Leu Asp
                 320                 325                 330

 Gly Met Ala Glu Leu Met Ala Gly Leu Met Gln Gly Val Asp His
                 335                 340                 345

 Gly Val Ala Arg Gly Ser Pro Gly Arg Ala Ala Leu Gly Glu Ser
                 350                 355                 360

 Gly Glu Gln Ala Asp Gly Pro Lys Ala Thr Leu Arg Gly Asp Ser
                 365                 370                 375

 Phe Pro Asp Asp Gly Val Gln Asp Asp Asp Asp Arg Leu Tyr Gln
                 380                 385                 390

 Glu Val His Arg Leu Ser Ala Thr Leu Gly Gly Leu Leu Gln Asp
                 395                 400                 405

 His Gly Ser Arg Leu Leu Pro Gly Ala Leu Pro Phe Ala Arg Pro
                 410                 415                 420

 Leu Asp Met Glu Arg Lys Lys Ser Glu His Pro Glu Ser Ser Leu
                 425                 430                 435

 Ser Ser Glu Glu Glu Thr Ala Gly Val Glu Asn Val Lys Ser Gln
                 440                 445                 450

 Thr Tyr Ser Lys Asp Leu Leu Gly Gln Gln Pro His Ser Glu Pro
                 455                 460                 465

 Gly Ala Ala Ala Phe Gly Glu Leu Gln Asn Gln Met Pro Gly Pro
                 470                 475                 480

 Ser Lys Glu Glu Gln Ser Leu Pro Ala Gly Ala Gln Glu Ala Leu
                 485                 490                 495

 Ser Asp Gly Leu Gln Leu Glu Val Gln Pro Ser Glu Glu Glu Ala
                 500                 505                 510

 Arg Gly Tyr Ile Val Thr Asp Arg Asp Pro Leu Arg Pro Glu Glu
                 515                 520                 525

 Gly Arg Arg Leu Val Glu Asp Val Ala Arg Leu Leu Gln Val Pro
                 530                 535                 540

 Ser Ser Ala Phe Ala Asp Val Glu Val Leu Gly Pro Ala Val Thr
                 545                 550                 555

 Phe Lys Val Ser Ala Asn Val Gln Asn Val Thr Thr Glu Asp Val
                 560                 565                 570

 Glu Lys Ala Thr Val Asp Asn Lys Asp Lys Leu Glu Glu Thr Ser
                 575                 580                 585

 Gly Leu Lys Ile Leu Gln Thr Gly Val Gly Ser Lys Ser Lys Leu
                 590                 595                 600

 Lys Phe Leu Pro Pro Gln Ala Glu Gln Glu Asp Ser Thr Lys Phe
                 605                 610                 615

 Ile Ala Leu Thr Leu Val Ser Leu Ala Cys Ile Leu Gly Val Leu
                 620                 625                 630

 Leu Ala Ser Gly Leu Ile Tyr Cys Leu Arg His Ser Ser Gln His
                 635                 640                 645

 Arg Leu Lys Glu Lys Leu Ser Gly Leu Gly Gly Asp Pro Gly Ala
                 650                 655                 660

 Asp Ala Thr Ala Ala Tyr Gln Glu Leu Cys Arg Gln Arg Met Ala
                 665                 670                 675

 Thr Arg Pro Pro Asp Arg Pro Glu Gly Pro His Thr Ser Arg Ile
                 680                 685                 690

 Ser Ser Val Ser Ser Gln Phe Ser Asp Gly Pro Ile Pro Ser Pro
                 695                 700                 705

 Ser Ala Arg Ser Ser Ala Ser Ser Trp Ser Glu Glu Pro Val Gln
                 710                 715                 720

 Ser Asn Met Asp Ile Ser Thr Gly His Met Ile Leu Ser Tyr Met
                 725                 730                 735

 Glu Asp His Leu Lys Asn Lys Asn Arg Leu Glu Lys Glu Trp Glu
                 740                 745                 750

 Ala Leu Cys Ala Tyr Gln Ala Glu Pro Asn Ser Ser Phe Val Ala
                 755                 760                 765

 Gln Arg Glu Glu Asn Val Pro Lys Asn Arg Ser Leu Ala Val Leu
                 770                 775                 780

 Thr Tyr Asp His Ser Arg Val Leu Leu Lys Ala Glu Asn Ser His
                 785                 790                 795

 Ser His Ser Asp Tyr Ile Asn Ala Ser Pro Ile Met Asp His Asp
                 800                 805                 810

 Pro Arg Asn Pro Ala Tyr Ile Ala Thr Gln Gly Pro Leu Pro Ala
                 815                 820                 825

 Thr Val Ala Asp Phe Trp Gln Met Val Trp Glu Ser Gly Cys Val
                 830                 835                 840

 Val Ile Val Met Leu Thr Pro Leu Ala Glu Asn Gly Val Arg Gln
                 845                 850                 855

 Cys Tyr His Tyr Trp Pro Asp Glu Gly Ser Asn Leu Tyr His Ile
                 860                 865                 870

 Tyr Glu Val Asn Leu Val Ser Glu His Ile Trp Cys Glu Asp Phe
                 875                 880                 885

 Leu Val Arg Ser Phe Tyr Leu Lys Asn Leu Gln Thr Asn Glu Thr
                 890                 895                 900

 Arg Thr Val Thr Gln Phe His Phe Leu Ser Trp Tyr Asp Arg Gly
                 905                 910                 915

 Val Pro Ser Ser Ser Arg Ser Leu Leu Asp Phe Arg Arg Lys Val
                 920                 925                 930

 Asn Lys Cys Tyr Arg Gly Arg Ser Cys Pro Ile Ile Val His Cys
                 935                 940                 945

 Ser Asp Gly Ala Gly Arg Ser Gly Thr Tyr Val Leu Ile Asp Met
                 950                 955                 960

 Val Leu Asn Lys Met Ala Lys Gly Ala Lys Glu Ile Asp Ile Ala
                 965                 970                 975

 Ala Thr Leu Glu His Leu Arg Asp Gln Arg Pro Gly Met Val Gln
                 980                 985                 990

 Thr Lys Glu Gln Phe Glu Phe Ala Leu Thr Ala Val Ala Glu Glu
                 995                1000                1005

 Val Asn Ala Ile Leu Lys Ala Leu Pro Gln
                1010                1015

<210> 777
<211> 4932
<212> DNA
<213> Homo sapien

<400> 777
 tgcgagcaac agatccggac gccgcgagct gacccgctct gctgttgggc 50

 gatttttttt taattgcaga aaaatttatt aaattggaaa atcttgcgtt 100

 tttcaatggc gctggccccg ggtcagcggg cgattttctc tgcatcaaga 150

 tgggctttgc cgtttccgta gtgggcacca gtggtggcct gattgtcagt 200

 cttctcccgg catttttaag gccaggagcc gagcgctgct tgtaggcgaa 250

 taccctacag agcggtttgg ctttttaaat tactgttatt attttgggca 300

 gagaacagtc ggtctggtgc accccgtcct cgctgcagaa gaggctgcga 350

 gtccgaggtg ggtctctcgg aaggtgaaat tccttctggg gtgagcgagc 400

 cccggccccg cgcgcagtcc agcggccccg cgtgtgtgcc ctcgccctgc 450

 cggagccggg aaaatggagg ctgtgattga gaaggaatgc agcgcgctcg 500

 gaggcctctt ccagaccatc atcagcgaca tgaaggggag ctatccagtt 550

 tgggaagatt tcataaacaa agcaggaaag ctgcagtccc agcttcggac 600

 aacagtagta gcagcagctg ccttcttgga cgcctttcag aaagtggctg 650

 acatggccac caacacacgt ggtgggacca gggagattgg atctgctctc 700

 accaggatgt gcatgaggca cagaagcatt gaagccaagc tgaggcagtt 750

 ttcgagcgct ttaattgatt gtctgataaa cccacttcaa gaacagatgg 800

 aagaatggaa gaaagtggcc aaccagctgg ataaagacca cgcaaaagaa 850

 tataagaaag cccgccaaga gataaaaaag aagtcctcgg atacgctgaa 900

 actgcagaag aaagcaaaaa aagggagagg tgatatccag cctcagttgg 950

 acagtgctct ccaagatgtc aatgataagt atctcttatt ggaagaaaca 1000

 gaaaagcagg ctgtccggaa ggctttgatt gaagaacgtg gccgattctg 1050

 taccttcatc tctatgctgc ggccagtgat tgaagaagaa atctcaatgc 1100

 taggggaaat aacccacctt cagaccatct cggaagatct aaaaagcctg 1150

 accatggacc ctcacaaact gccctcctca agtgaacagg tgattctgga 1200

 cttgaaaggt tctgattaca gctggtcgta tcagacgcca ccctcttccc 1250

 ccagcaccac catgtccaga aagtccagtg tctgcagcag cctgaacagt 1300

 gtcaacagca gtgactcccg gtccagcggc tcccactcgc attcccccag 1350

 ctcacattac cgctaccgca gctccaacct ggcccagcag gctcctgtga 1400

 ggctgtccag cgtgtcctcc catgactcag gattcatatc ccaggatgcc 1450

 ttccagtcca agtcaccatc ccccatgccg ccagaggccc ccaaccagtt 1500

 gtctaacggg ttttctcact atagtttatc aagtgagtcc cacgtggggc 1550

 ccacgggtgc aggccttttc cctcattgcc tgcctgcctc ccgcctgctc 1600

 cctcgggtca cctctgtcca ccttccagac tacgctcatt attacaccat 1650

 tgggcccggc atgttcccgt catctcagat ccctagctgg aaggactggg 1700

 ctaagcctgg gccctatgac cagcctctgg tgaacaccct gcagcgccgc 1750

 aaagagaagc gagaaccgga ccccaacggg ggaggaccca ctaccgccag 1800

 cggcccacct gcagcagctg aggaggctca gagaccacgg agcatgactg 1850

 tatcggctgc caccaggcct ggtgaggaga tggaggcttg tgaggagctg 1900

 gccctggccc tgtctcgggg cctgcagctg gacacccaga ggagcagccg 1950

 ggactcgctt cagtgctcca gcggctacag cacccagaca accaccccct 2000

 gctgctctga ggacaccatc ccttcccaag tttcagatta tgattatttc 2050

 tctgtaagtg gtgaccagga ggcagatcag caggagttcg acaagtcctc 2100

 caccattcca agaaacagcg acatcagcca gtcctaccga cggatgttcc 2150

 aagccaagcg tccagcctca actgctggcc tccccaccac cctgggacct 2200

 gctatggtca ctccaggggt tgcaactatc cgacggaccc cttccaccaa 2250

 gccttctgtc cgccggggaa ccattggagc tggtcccatc cccatcaaga 2300

 cacccgtgat ccctgtcaag accccaaccg tcccagacct cccaggggtg 2350

 atgccagccc ctccagatgg gccagaagag cggggggagc acagccctga 2400

 gtcgccatct gtgggtgagg gcccccaagg tgtcaccagc atgccctcct 2450

 caatgtggag cggccaagct tccgttaacc ctccacttcc aggcccgaag 2500

 cccagtatcc ctgaggagca cagacaggca attccagaaa gtgaagctga 2550

 agaccaggaa cgggaacccc caagtgccac tgtctcccca ggccagattc 2600

 cagagagtga ccctgcagac ctgagcccaa gggatactcc acaaggagaa 2650

 gacatgctga acgccatccg aaggggcgtg aaactgaaga agaccacgac 2700

 aaacgatcgc tcagcccctc gcttttctta ggttcacaag aaatgcgccg 2750

 gtggggaatg aactgtttca ttaataaaac ctaatttgtc ttgatccatt 2800

 ccactctata ataaaacaaa agattttgta ggcaactcgg aatatagctc 2850

 ttttgaaagt actcgacacc tttagataag aattaaaacc aacctatgta 2900

 actgacataa tcttgatctt ttaatttgta aatattgaca attttctttc 2950

 tgcacatttt aatcttagtt tcccttttga tttttctgaa ggtgccaaat 3000

 tccatttaac ttttttacaa gtctttgtaa aattttaaat gcataaaggg 3050

 ggttggggca ggggaaccac gaagtagtta attttagaaa aggatttact 3100

 atacttcact cttctttttt tttccccaca agcttttgta gatgcattgt 3150

 agtagtctag cttagaagca aatgcaagtt attttaatgt acaaactaaa 3200

 tgggtaagag gtaaaatctt catttaaata tactatgttc tggatgaaaa 3250

 gagcaggagt aacaattgat gagcaatatt cagagtgaag taaatctgga 3300

 aatggtagac tgtgttggga ttggggggag ggccatggga ggggtacatc 3350

 gtcaacatag ccgatcctgt tacatttaag agtagcctcg taggttgaat 3400

 ttcttctggt agcttcatgg taaatgcatc cgaataagcc atactggatt 3450

 gcagtgtttg tttctgtagg gtgtttaagg acttgacttc ctttctccca 3500

 tgattcctct ggactgcaca cagcacccac aaccagcccc atgcatgctg 3550

 ctgcctctgg gcagtcgtag aatctcccac ttcagtttct cgttgattgt 3600

 actcaccttt atggaatcca aatacatcca aaagggtaag gcagttttaa 3650

 aaatgtgaaa acatttaaaa atgataatag cagggaattc ttagattata 3700

 gtaaatgcct tttacttaac tgtgcccagc aggctgggtg cgttaaaaag 3750

 cccaagtatt ttgaaaaaac tcgaacagat ttgacaaggg tagccagctt 3800

 ggagtctagc aacttgccaa tgtgtttacc aatctggggg cttgtttttc 3850

 ttttcttctt tcaaataaat ggcagttaac tggctttaca gtaaacattg 3900

 aagagaggag gatttgttta ttgtcactgg gaatctgacc actatactgt 3950

 cctttttttg tattctgggt aatgtttttt ggaaaagatt tgtcttttct 4000

 aagtggaagt taaatttgtt atactgccca tcccctaaag ccaacagaga 4050

 tttgtagatt taaagggatc acatttgaag acaatagtgt ttaagaaagc 4100

 aagcaagtcc cttagcagtc aggtcataac agggcacatt tctgaccgaa 4150

 ccctctcaag gcagaggagg agtttggtgg gtttcataca ccctgcagat 4200

 tcctgttggc tctaaccctc aattacctaa tcttatgctt taacacataa 4250

 ctgcattgga tgtgagagta acgtaccgta tggtcattgt tctatatatt 4300

 aacattgaac actgctgcga ttgctcaagg acattttatg ttacggcttt 4350

 aaagcaaagg catgattatt agaaactatt taagcttttt tctttgaaaa 4400

 acaagcttct tttacagaat ataaacaaca gtagtgcctg tggtttagcc 4450

 caccaatctt gatgactaaa agtagctgat gcattgtgca tatgatgctt 4500

 gagatggttt ttgcaaaagc agaaatcgct gcaaggtaat cacaatagat 4550

 aaaagtggta ttttaaacct ttgaaataaa tggatgtaac tgtaccttgg 4600

 tacagctttt cacttgttta gtttttaaac gttagtataa tctgaataaa 4650

 taaaatgttg ccaaattcaa tgtagaaaga atgtgacaac acaccttggg 4700

 tagttctgct tgtgtttttg catattgtaa aagcagtgtc acagctaaaa 4750

 agaaagaaat cgtttctaac agtaaattat tgtgctttag ttgctagttt 4800

 gtactgagag ttgacctctc cctgtgcagt tttttgttct aaacttgtat 4850

 aaataacaat tgtgtaatgt gtctccctcc tacattgtaa caattgcttc 4900

 agcctacgtt ataaataaag aaccactaga tt 4932

<210> 778
<211> 755
<212> PRT
<213> Homo sapien

<400> 778
 Met Glu Ala Val Ile Glu Lys Glu Cys Ser Ala Leu Gly Gly Leu
   1               5                  10                  15

 Phe Gln Thr Ile Ile Ser Asp Met Lys Gly Ser Tyr Pro Val Trp
                  20                  25                  30

 Glu Asp Phe Ile Asn Lys Ala Gly Lys Leu Gln Ser Gln Leu Arg
                  35                  40                  45

 Thr Thr Val Val Ala Ala Ala Ala Phe Leu Asp Ala Phe Gln Lys
                  50                  55                  60

 Val Ala Asp Met Ala Thr Asn Thr Arg Gly Gly Thr Arg Glu Ile
                  65                  70                  75

 Gly Ser Ala Leu Thr Arg Met Cys Met Arg His Arg Ser Ile Glu
                  80                  85                  90

 Ala Lys Leu Arg Gln Phe Ser Ser Ala Leu Ile Asp Cys Leu Ile
                  95                 100                 105

 Asn Pro Leu Gln Glu Gln Met Glu Glu Trp Lys Lys Val Ala Asn
                 110                 115                 120

 Gln Leu Asp Lys Asp His Ala Lys Glu Tyr Lys Lys Ala Arg Gln
                 125                 130                 135

 Glu Ile Lys Lys Lys Ser Ser Asp Thr Leu Lys Leu Gln Lys Lys
                 140                 145                 150

 Ala Lys Lys Gly Arg Gly Asp Ile Gln Pro Gln Leu Asp Ser Ala
                 155                 160                 165

 Leu Gln Asp Val Asn Asp Lys Tyr Leu Leu Leu Glu Glu Thr Glu
                 170                 175                 180

 Lys Gln Ala Val Arg Lys Ala Leu Ile Glu Glu Arg Gly Arg Phe
                 185                 190                 195

 Cys Thr Phe Ile Ser Met Leu Arg Pro Val Ile Glu Glu Glu Ile
                 200                 205                 210

 Ser Met Leu Gly Glu Ile Thr His Leu Gln Thr Ile Ser Glu Asp
                 215                 220                 225

 Leu Lys Ser Leu Thr Met Asp Pro His Lys Leu Pro Ser Ser Ser
                 230                 235                 240

 Glu Gln Val Ile Leu Asp Leu Lys Gly Ser Asp Tyr Ser Trp Ser
                 245                 250                 255

 Tyr Gln Thr Pro Pro Ser Ser Pro Ser Thr Thr Met Ser Arg Lys
                 260                 265                 270

 Ser Ser Val Cys Ser Ser Leu Asn Ser Val Asn Ser Ser Asp Ser
                 275                 280                 285

 Arg Ser Ser Gly Ser His Ser His Ser Pro Ser Ser His Tyr Arg
                 290                 295                 300

 Tyr Arg Ser Ser Asn Leu Ala Gln Gln Ala Pro Val Arg Leu Ser
                 305                 310                 315

 Ser Val Ser Ser His Asp Ser Gly Phe Ile Ser Gln Asp Ala Phe
                 320                 325                 330

 Gln Ser Lys Ser Pro Ser Pro Met Pro Pro Glu Ala Pro Asn Gln
                 335                 340                 345

 Leu Ser Asn Gly Phe Ser His Tyr Ser Leu Ser Ser Glu Ser His
                 350                 355                 360

 Val Gly Pro Thr Gly Ala Gly Leu Phe Pro His Cys Leu Pro Ala
                 365                 370                 375

 Ser Arg Leu Leu Pro Arg Val Thr Ser Val His Leu Pro Asp Tyr
                 380                 385                 390

 Ala His Tyr Tyr Thr Ile Gly Pro Gly Met Phe Pro Ser Ser Gln
                 395                 400                 405

 Ile Pro Ser Trp Lys Asp Trp Ala Lys Pro Gly Pro Tyr Asp Gln
                 410                 415                 420

 Pro Leu Val Asn Thr Leu Gln Arg Arg Lys Glu Lys Arg Glu Pro
                 425                 430                 435

 Asp Pro Asn Gly Gly Gly Pro Thr Thr Ala Ser Gly Pro Pro Ala
                 440                 445                 450

 Ala Ala Glu Glu Ala Gln Arg Pro Arg Ser Met Thr Val Ser Ala
                 455                 460                 465

 Ala Thr Arg Pro Gly Glu Glu Met Glu Ala Cys Glu Glu Leu Ala
                 470                 475                 480

 Leu Ala Leu Ser Arg Gly Leu Gln Leu Asp Thr Gln Arg Ser Ser
                 485                 490                 495

 Arg Asp Ser Leu Gln Cys Ser Ser Gly Tyr Ser Thr Gln Thr Thr
                 500                 505                 510

 Thr Pro Cys Cys Ser Glu Asp Thr Ile Pro Ser Gln Val Ser Asp
                 515                 520                 525

 Tyr Asp Tyr Phe Ser Val Ser Gly Asp Gln Glu Ala Asp Gln Gln
                 530                 535                 540

 Glu Phe Asp Lys Ser Ser Thr Ile Pro Arg Asn Ser Asp Ile Ser
                 545                 550                 555

 Gln Ser Tyr Arg Arg Met Phe Gln Ala Lys Arg Pro Ala Ser Thr
                 560                 565                 570

 Ala Gly Leu Pro Thr Thr Leu Gly Pro Ala Met Val Thr Pro Gly
                 575                 580                 585

 Val Ala Thr Ile Arg Arg Thr Pro Ser Thr Lys Pro Ser Val Arg
                 590                 595                 600

 Arg Gly Thr Ile Gly Ala Gly Pro Ile Pro Ile Lys Thr Pro Val
                 605                 610                 615

 Ile Pro Val Lys Thr Pro Thr Val Pro Asp Leu Pro Gly Val Met
                 620                 625                 630

 Pro Ala Pro Pro Asp Gly Pro Glu Glu Arg Gly Glu His Ser Pro
                 635                 640                 645

 Glu Ser Pro Ser Val Gly Glu Gly Pro Gln Gly Val Thr Ser Met
                 650                 655                 660

 Pro Ser Ser Met Trp Ser Gly Gln Ala Ser Val Asn Pro Pro Leu
                 665                 670                 675

 Pro Gly Pro Lys Pro Ser Ile Pro Glu Glu His Arg Gln Ala Ile
                 680                 685                 690

 Pro Glu Ser Glu Ala Glu Asp Gln Glu Arg Glu Pro Pro Ser Ala
                 695                 700                 705

 Thr Val Ser Pro Gly Gln Ile Pro Glu Ser Asp Pro Ala Asp Leu
                 710                 715                 720

 Ser Pro Arg Asp Thr Pro Gln Gly Glu Asp Met Leu Asn Ala Ile
                 725                 730                 735

 Arg Arg Gly Val Lys Leu Lys Lys Thr Thr Thr Asn Asp Arg Ser
                 740                 745                 750

 Ala Pro Arg Phe Ser
                 755

<210> 779
<211> 5982
<212> DNA
<213> Homo sapien

<400> 779
 cgagcatgga gagctgccgc cgcggccggc cggcgacgct ggcgacgctt 50

 tcgcccctga ggtagtttgg cgaccgcgaa gaaggaaaaa gggcgggcgg 100

 gcggctgtcc tctcaccgtc ctcaccccgc gaggcccggc ccgctcctcc 150

 gtcgtggatt tcgcggcgat ccccccggca gctctttgca aagctgcttg 200

 aaacttctcc caaactcggc atggatacga ctgcggcggc ggcgctgcct 250

 gcttttgtgg cgctcttgct cctctctcct tggcctctcc tgggatcggc 300

 ccaaggccag ttctccgcag gtggctgtac ttttgatgat ggtccagggg 350

 cctgtgatta ccaccaggat ctgtatgatg actttgaatg ggtgcatgtt 400

 agtgctcaag agcctcatta tctaccaccc gagatgcccc aaggttccta 450

 tatgatagtg gactcttcag atcacgaccc tggagaaaaa gccagacttc 500

 agctgcctac aatgaaggag aacgacactc actgcattga tttcagttac 550

 ctattatata gccagaaagg actgaatcct ggcactttga acatattagt 600

 tagggtgaat aaaggacctc ttgccaatcc aatttggaat gtgactggat 650

 tcacgggtag agattggctt cgggctgagc tagcagtgag caccttttgg 700

 cccaatgaat atcaggtaat atttgaagct gaagtctcag gagggagaag 750

 tggttatatt gccattgatg acatccaagt actgagttat ccttgtgata 800

 aatctcctca tttcctccgt ctaggggatg tagaggtgaa tgcagggcaa 850

 aacgctacat ttcagtgcat tgccacaggg agagatgctg tgcataacaa 900

 gttatggctc cagagacgaa atggagaaga tataccagta gcccagacta 950

 agaacatcaa tcatagaagg tttgccgctt ccttcagatt gcaagaagtg 1000

 acaaaaactg accaggattt gtatcgctgt gtaactcagt cagaacgagg 1050

 ttccggtgtg tccaattttg ctcaacttat tgtgagagaa ccgccaagac 1100

 ccattgctcc tcctcagctt cttggtgttg ggcctacata tttgctgatc 1150

 caactaaatg ccaactcgat cattggcgat ggtcctatca tcctgaaaga 1200

 agtagagtac cgaatgacat caggatcctg gacagaaacc catgcagtca 1250

 atgctccaac ttacaaatta tggcatttag atccagatac cgaatatgag 1300

 atccgagttc tacttacaag acctggtgaa ggtggaacgg ggctcccagg 1350

 acctccacta atcaccagaa caaaatgtgc agaacctatg agaaccccaa 1400

 agacattaaa gattgctgaa atacaggcaa gacggattgc tgtggactgg 1450

 gaatccttgg gttacaacat tacgcgttgc cacactttta atgtcactat 1500

 ctgctaccat tacttccgtg gtcacaacga gagcaaggca gactgtttgg 1550

 acatggaccc caaagcccct cagcatgttg tgaaccatct gccaccttat 1600

 acaaatgtca gcctcaagat gatcctaacc aatccagagg gaaggaagga 1650

 gagtgaagag acaattattc aaactgatga agatgtgcct ggtcccgtac 1700

 cagtaaaatc tcttcaagga acatcctttg aaaataagat cttcttgaac 1750

 tggaaagaac ctttggatcc aaatggaatc atcactcaat atgagatcag 1800

 ctatagcagt ataagatcat ttgatcctgc agttccagtg gctggacctc 1850

 cccagactgt atcaaattta tggaacagta cacaccatgt ctttatgcat 1900

 ctccaccctg gaaccacgta ccagtttttc ataagagcca gcacggtcaa 1950

 aggctttggt ccagccacag ccatcaatgt caccaccaat atctcagctc 2000

 caactttacc tgactatgaa ggagttgatg cctctctcaa tgaaactgcc 2050

 accacaataa ctgtattgtt gagaccagca caagccaaag gtgctcctat 2100

 cagtgcttat cagattgttg tggaagaact gcacccacac cgaaccaaga 2150

 gagaagccgg agccatggaa tgctaccagg ttcctgtcac ataccaaaat 2200

 gccatgagtg ggggtgcacc gtattacttt gctgcagaac tccccccggg 2250

 aaacctacct gagcctgccc cgttcactgt gggtgacaat cggacctacc 2300

 aaggcttttg gaaccctcct ttggctccgc gcaaaggata caacatctat 2350

 ttccaggcga tgagcagtgt ggagaaggaa actaaaaccc agtgcgtacg 2400

 cattgctaca aaagcagcag caacagaaga accagaagtg atcccagatc 2450

 ccgccaagca gacagacaga gtggtgaaaa tagcaggaat tagtgctgga 2500

 attttggtgt tcatcctcct tctcctagtt gtcatattaa ttgtaaaaaa 2550

 gagcaaactt gctaaaaaac gcaaagatgc catggggaat acccggcagg 2600

 agatgactca catggtgaat gcaatggatc gaagttatgc tgatcagagc 2650

 actctgcatg cagaagatcc tctttccatc accttcatgg accaacataa 2700

 ctttagtcca agatatgaga accacagtgc tacagcagag tccagtcgcc 2750

 ttctagacgt acctcgctac ctctgtgagg ggacggaatc cccttaccag 2800

 acaggacagc tgcatccagc catcagggta gctgatttac tgcagcacat 2850

 taatctcatg aagacatcag acagctatgg gttcaaagag gaatatgaga 2900

 gcttttttga aggacagtca gcatcttggg atgtagctaa aaaagatcaa 2950

 aatagagcaa aaaaccgata tggaaacatt atagcatatg atcactccag 3000

 agtgattttg caacccgtag aggatgatcc ttcctcagat tatattaatg 3050

 ccaactatat tgatggctac cagagaccaa gtcattacat tgcaacccaa 3100

 ggtcccgttc atgaaacagt gtatgatttc tggaggatga tttggcaaga 3150

 acaatctgct tgcattgtga tggttacaaa tttagttgag gttggccggg 3200

 ttaaatgcta taaatattgg cctgatgata ctgaagttta tggtgacttc 3250

 aaagtaacgt gtgtagaaat ggaaccactt gctgaatatg tagttaggac 3300

 attcaccctg gaaaggaggg ggtacaatga aatccgtgaa gttaaacagt 3350

 tccatttcac gggctggcct gaccatggag tgccctacca tgctacaggg 3400

 ctgctttcct ttatccggcg agtcaagtta tcaaaccctc ccagtgctgg 3450

 ccccatcgtt gtacattgca gtgctggtgc tggacgaact ggctgctaca 3500

 ttgtgattga catcatgcta gacatggctg aaagagaggg tgttgttgat 3550

 atttacaatt gtgtcaaagc cttaagatct cggcgtatta atatggtcca 3600

 gacagaggaa cagtacattt ttattcatga tgccatttta gaagcctgct 3650

 tatgtggaga aactgccata cctgtctgtg aatttaaagc tgcatatttt 3700

 gatatgatta gaatagactc ccagactaac tcttcacatc tcaaggatga 3750

 atttcagact ctgaattcag tcacccctcg actacaagct gaagactgca 3800

 gtatagcgtg cctgccaagg aaccatgaca agaaccgttt catggacatg 3850

 ctgccacctg acagatgtct gcctttttta attacaattg atggggagag 3900

 cagtaactac atcaatgctg ctcttatgga cagctacagg caaccagctg 3950

 ctttcatcgt cacacaatac cctctgccaa acactgtaaa agacttctgg 4000

 agattagtgt atgattatgg ctgtacctcc attgtgatgt taaacgaagt 4050

 cgacttgtcc cagggctgcc ctcagtactg gccagaggaa gggatgctac 4100

 gatatggccc catccaagtg gaatgtatgt cttgttcaat ggactgtgat 4150

 gtgatcaacc ggatttttag gatatgcaat ctaacaagac cacaggaagg 4200

 ttatctgatg gtgcaacagt ttcagtacct aggatgggct tctcatcgag 4250

 aagtgcctgg atccaaaagg tcattcttga aactgatact tcaggtggaa 4300

 aagtggcagg aggaatgcga ggaaggggaa ggccggacga ttatccactg 4350

 cctaaatggt ggcgggcgaa gtggcatgtt ctgtgctata ggcatcgttg 4400

 ttgaaatggt gaaacggcaa aatgttgtcg atgttttcca tgcagtaaag 4450

 acactgagga acagcaagcc aaacatggtg gaagccccgg agcaataccg 4500

 tttctgctat gatgtagctt tggagtacct ggaatcatct tagttgggtg 4550

 agactcttta aagtgcatcc atgaagaaac ctgtccatct attgagccag 4600

 cagctgttgt acctgttaca cttgtgcaga aagattttaa tgtggggggt 4650

 gggagacttt tacatttgag aggtaaaagt atttttttta tgaagttgtg 4700

 tatcttaata aaaaggactg aattagtttt tattactata ttaaagcatc 4750

 aacatttcat gccacataaa ttatatttaa taagaaccag attgaaatga 4800

 gaacgtattg gtgtttgtac agtgaacatg ccaccttttt tctcatggtt 4850

 tcagtagagc agctaccaca tgttgcatga gttcatactt tctacgtggc 4900

 atttttctcc ctttctaaaa tgaaagctga tgaatcttaa aaggaagaag 4950

 aaaagaaaag ctgtgcaaat tcatagtaaa gttcgttttt tatatgtttc 5000

 cagtgtagca gatctctata taaatatata aatatatata actggcttat 5050

 tttcttttaa tgtgcaatga tggctggatc atttaaagtt ctttttagaa 5100

 aataacataa gccaaagact caagtgtaaa tatgtctata tggagaaagc 5150

 acattatatt tattggttac ttacattcct tttttgatgg ctaaaatact 5200

 accaccacac aatcatcttt ttttcctgaa gaaagctttt tctttagcta 5250

 aaatcaattg taaacgattt ttgtagatta ttttttgtat gttttagtgt 5300

 aagtagaaga taaacttttt attcataaac caggaagcaa tgttctttat 5350

 agtgattctc ttgtgtacat gcttgtgaat taaatttgtg taaaatccct 5400

 tggcaattgg gtcttttaat ataggaccaa attaaaacat tttgctgaat 5450

 atgtatagtt tttcacaatt tcattaggta aataatggtt tggtgatcat 5500

 acatgagaaa tgtacacatt aaaaggcctt gctgacaact tgcacaatgt 5550

 tgaacatagc ctttaagcat catttaaatt ttaaaggaat ggagtttttc 5600

 agcctgtggc ccagcactgg tcaagaaaac aagatggcaa catatatgct 5650

 ttcagggtca aatttgagca aactgtaaac tgtcagggtg ataaaatgtt 5700

 tctcttgatg tttacatgca caagctttgc gttctgacta taaaaagtgt 5750

 gaacaaatca atgccagatt cctgttttgc gcattgtcat gggattctta 5800

 agtgaacctt tctaaatgtg gtcttgttca catgctccac gtagctgtaa 5850

 cttcacatca tcagcttgca gtttgtaatt gactaaagca ttccagtgtc 5900

 ctctttctag attgccagct catgacatgg tgcttataaa gatttaatta 5950

 aagtaagaat gaaataaagt ttttataatt at 5982

<210> 780
<211> 1440
<212> PRT
<213> Homo sapien

<400> 780
 Met Asp Thr Thr Ala Ala Ala Ala Leu Pro Ala Phe Val Ala Leu
   1               5                  10                  15

 Leu Leu Leu Ser Pro Trp Pro Leu Leu Gly Ser Ala Gln Gly Gln
                  20                  25                  30

 Phe Ser Ala Gly Gly Cys Thr Phe Asp Asp Gly Pro Gly Ala Cys
                  35                  40                  45

 Asp Tyr His Gln Asp Leu Tyr Asp Asp Phe Glu Trp Val His Val
                  50                  55                  60

 Ser Ala Gln Glu Pro His Tyr Leu Pro Pro Glu Met Pro Gln Gly
                  65                  70                  75

 Ser Tyr Met Ile Val Asp Ser Ser Asp His Asp Pro Gly Glu Lys
                  80                  85                  90

 Ala Arg Leu Gln Leu Pro Thr Met Lys Glu Asn Asp Thr His Cys
                  95                 100                 105

 Ile Asp Phe Ser Tyr Leu Leu Tyr Ser Gln Lys Gly Leu Asn Pro
                 110                 115                 120

 Gly Thr Leu Asn Ile Leu Val Arg Val Asn Lys Gly Pro Leu Ala
                 125                 130                 135

 Asn Pro Ile Trp Asn Val Thr Gly Phe Thr Gly Arg Asp Trp Leu
                 140                 145                 150

 Arg Ala Glu Leu Ala Val Ser Thr Phe Trp Pro Asn Glu Tyr Gln
                 155                 160                 165

 Val Ile Phe Glu Ala Glu Val Ser Gly Gly Arg Ser Gly Tyr Ile
                 170                 175                 180

 Ala Ile Asp Asp Ile Gln Val Leu Ser Tyr Pro Cys Asp Lys Ser
                 185                 190                 195

 Pro His Phe Leu Arg Leu Gly Asp Val Glu Val Asn Ala Gly Gln
                 200                 205                 210

 Asn Ala Thr Phe Gln Cys Ile Ala Thr Gly Arg Asp Ala Val His
                 215                 220                 225

 Asn Lys Leu Trp Leu Gln Arg Arg Asn Gly Glu Asp Ile Pro Val
                 230                 235                 240

 Ala Gln Thr Lys Asn Ile Asn His Arg Arg Phe Ala Ala Ser Phe
                 245                 250                 255

 Arg Leu Gln Glu Val Thr Lys Thr Asp Gln Asp Leu Tyr Arg Cys
                 260                 265                 270

 Val Thr Gln Ser Glu Arg Gly Ser Gly Val Ser Asn Phe Ala Gln
                 275                 280                 285

 Leu Ile Val Arg Glu Pro Pro Arg Pro Ile Ala Pro Pro Gln Leu
                 290                 295                 300

 Leu Gly Val Gly Pro Thr Tyr Leu Leu Ile Gln Leu Asn Ala Asn
                 305                 310                 315

 Ser Ile Ile Gly Asp Gly Pro Ile Ile Leu Lys Glu Val Glu Tyr
                 320                 325                 330

 Arg Met Thr Ser Gly Ser Trp Thr Glu Thr His Ala Val Asn Ala
                 335                 340                 345

 Pro Thr Tyr Lys Leu Trp His Leu Asp Pro Asp Thr Glu Tyr Glu
                 350                 355                 360

 Ile Arg Val Leu Leu Thr Arg Pro Gly Glu Gly Gly Thr Gly Leu
                 365                 370                 375

 Pro Gly Pro Pro Leu Ile Thr Arg Thr Lys Cys Ala Glu Pro Met
                 380                 385                 390

 Arg Thr Pro Lys Thr Leu Lys Ile Ala Glu Ile Gln Ala Arg Arg
                 395                 400                 405

 Ile Ala Val Asp Trp Glu Ser Leu Gly Tyr Asn Ile Thr Arg Cys
                 410                 415                 420

 His Thr Phe Asn Val Thr Ile Cys Tyr His Tyr Phe Arg Gly His
                 425                 430                 435

 Asn Glu Ser Lys Ala Asp Cys Leu Asp Met Asp Pro Lys Ala Pro
                 440                 445                 450

 Gln His Val Val Asn His Leu Pro Pro Tyr Thr Asn Val Ser Leu
                 455                 460                 465

 Lys Met Ile Leu Thr Asn Pro Glu Gly Arg Lys Glu Ser Glu Glu
                 470                 475                 480

 Thr Ile Ile Gln Thr Asp Glu Asp Val Pro Gly Pro Val Pro Val
                 485                 490                 495

 Lys Ser Leu Gln Gly Thr Ser Phe Glu Asn Lys Ile Phe Leu Asn
                 500                 505                 510

 Trp Lys Glu Pro Leu Asp Pro Asn Gly Ile Ile Thr Gln Tyr Glu
                 515                 520                 525

 Ile Ser Tyr Ser Ser Ile Arg Ser Phe Asp Pro Ala Val Pro Val
                 530                 535                 540

 Ala Gly Pro Pro Gln Thr Val Ser Asn Leu Trp Asn Ser Thr His
                 545                 550                 555

 His Val Phe Met His Leu His Pro Gly Thr Thr Tyr Gln Phe Phe
                 560                 565                 570

 Ile Arg Ala Ser Thr Val Lys Gly Phe Gly Pro Ala Thr Ala Ile
                 575                 580                 585

 Asn Val Thr Thr Asn Ile Ser Ala Pro Thr Leu Pro Asp Tyr Glu
                 590                 595                 600

 Gly Val Asp Ala Ser Leu Asn Glu Thr Ala Thr Thr Ile Thr Val
                 605                 610                 615

 Leu Leu Arg Pro Ala Gln Ala Lys Gly Ala Pro Ile Ser Ala Tyr
                 620                 625                 630

 Gln Ile Val Val Glu Glu Leu His Pro His Arg Thr Lys Arg Glu
                 635                 640                 645

 Ala Gly Ala Met Glu Cys Tyr Gln Val Pro Val Thr Tyr Gln Asn
                 650                 655                 660

 Ala Met Ser Gly Gly Ala Pro Tyr Tyr Phe Ala Ala Glu Leu Pro
                 665                 670                 675

 Pro Gly Asn Leu Pro Glu Pro Ala Pro Phe Thr Val Gly Asp Asn
                 680                 685                 690

 Arg Thr Tyr Gln Gly Phe Trp Asn Pro Pro Leu Ala Pro Arg Lys
                 695                 700                 705

 Gly Tyr Asn Ile Tyr Phe Gln Ala Met Ser Ser Val Glu Lys Glu
                 710                 715                 720

 Thr Lys Thr Gln Cys Val Arg Ile Ala Thr Lys Ala Ala Ala Thr
                 725                 730                 735

 Glu Glu Pro Glu Val Ile Pro Asp Pro Ala Lys Gln Thr Asp Arg
                 740                 745                 750

 Val Val Lys Ile Ala Gly Ile Ser Ala Gly Ile Leu Val Phe Ile
                 755                 760                 765

 Leu Leu Leu Leu Val Val Ile Leu Ile Val Lys Lys Ser Lys Leu
                 770                 775                 780

 Ala Lys Lys Arg Lys Asp Ala Met Gly Asn Thr Arg Gln Glu Met
                 785                 790                 795

 Thr His Met Val Asn Ala Met Asp Arg Ser Tyr Ala Asp Gln Ser
                 800                 805                 810

 Thr Leu His Ala Glu Asp Pro Leu Ser Ile Thr Phe Met Asp Gln
                 815                 820                 825

 His Asn Phe Ser Pro Arg Tyr Glu Asn His Ser Ala Thr Ala Glu
                 830                 835                 840

 Ser Ser Arg Leu Leu Asp Val Pro Arg Tyr Leu Cys Glu Gly Thr
                 845                 850                 855

 Glu Ser Pro Tyr Gln Thr Gly Gln Leu His Pro Ala Ile Arg Val
                 860                 865                 870

 Ala Asp Leu Leu Gln His Ile Asn Leu Met Lys Thr Ser Asp Ser
                 875                 880                 885

 Tyr Gly Phe Lys Glu Glu Tyr Glu Ser Phe Phe Glu Gly Gln Ser
                 890                 895                 900

 Ala Ser Trp Asp Val Ala Lys Lys Asp Gln Asn Arg Ala Lys Asn
                 905                 910                 915

 Arg Tyr Gly Asn Ile Ile Ala Tyr Asp His Ser Arg Val Ile Leu
                 920                 925                 930

 Gln Pro Val Glu Asp Asp Pro Ser Ser Asp Tyr Ile Asn Ala Asn
                 935                 940                 945

 Tyr Ile Asp Gly Tyr Gln Arg Pro Ser His Tyr Ile Ala Thr Gln
                 950                 955                 960

 Gly Pro Val His Glu Thr Val Tyr Asp Phe Trp Arg Met Ile Trp
                 965                 970                 975

 Gln Glu Gln Ser Ala Cys Ile Val Met Val Thr Asn Leu Val Glu
                 980                 985                 990

 Val Gly Arg Val Lys Cys Tyr Lys Tyr Trp Pro Asp Asp Thr Glu
                 995                1000                1005

 Val Tyr Gly Asp Phe Lys Val Thr Cys Val Glu Met Glu Pro Leu
                1010                1015                1020

 Ala Glu Tyr Val Val Arg Thr Phe Thr Leu Glu Arg Arg Gly Tyr
                1025                1030                1035

 Asn Glu Ile Arg Glu Val Lys Gln Phe His Phe Thr Gly Trp Pro
                1040                1045                1050

 Asp His Gly Val Pro Tyr His Ala Thr Gly Leu Leu Ser Phe Ile
                1055                1060                1065

 Arg Arg Val Lys Leu Ser Asn Pro Pro Ser Ala Gly Pro Ile Val
                1070                1075                1080

 Val His Cys Ser Ala Gly Ala Gly Arg Thr Gly Cys Tyr Ile Val
                1085                1090                1095

 Ile Asp Ile Met Leu Asp Met Ala Glu Arg Glu Gly Val Val Asp
                1100                1105                1110

 Ile Tyr Asn Cys Val Lys Ala Leu Arg Ser Arg Arg Ile Asn Met
                1115                1120                1125

 Val Gln Thr Glu Glu Gln Tyr Ile Phe Ile His Asp Ala Ile Leu
                1130                1135                1140

 Glu Ala Cys Leu Cys Gly Glu Thr Ala Ile Pro Val Cys Glu Phe
                1145                1150                1155

 Lys Ala Ala Tyr Phe Asp Met Ile Arg Ile Asp Ser Gln Thr Asn
                1160                1165                1170

 Ser Ser His Leu Lys Asp Glu Phe Gln Thr Leu Asn Ser Val Thr
                1175                1180                1185

 Pro Arg Leu Gln Ala Glu Asp Cys Ser Ile Ala Cys Leu Pro Arg
                1190                1195                1200

 Asn His Asp Lys Asn Arg Phe Met Asp Met Leu Pro Pro Asp Arg
                1205                1210                1215

 Cys Leu Pro Phe Leu Ile Thr Ile Asp Gly Glu Ser Ser Asn Tyr
                1220                1225                1230

 Ile Asn Ala Ala Leu Met Asp Ser Tyr Arg Gln Pro Ala Ala Phe
                1235                1240                1245

 Ile Val Thr Gln Tyr Pro Leu Pro Asn Thr Val Lys Asp Phe Trp
                1250                1255                1260

 Arg Leu Val Tyr Asp Tyr Gly Cys Thr Ser Ile Val Met Leu Asn
                1265                1270                1275

 Glu Val Asp Leu Ser Gln Gly Cys Pro Gln Tyr Trp Pro Glu Glu
                1280                1285                1290

 Gly Met Leu Arg Tyr Gly Pro Ile Gln Val Glu Cys Met Ser Cys
                1295                1300                1305

 Ser Met Asp Cys Asp Val Ile Asn Arg Ile Phe Arg Ile Cys Asn
                1310                1315                1320

 Leu Thr Arg Pro Gln Glu Gly Tyr Leu Met Val Gln Gln Phe Gln
                1325                1330                1335

 Tyr Leu Gly Trp Ala Ser His Arg Glu Val Pro Gly Ser Lys Arg
                1340                1345                1350

 Ser Phe Leu Lys Leu Ile Leu Gln Val Glu Lys Trp Gln Glu Glu
                1355                1360                1365

 Cys Glu Glu Gly Glu Gly Arg Thr Ile Ile His Cys Leu Asn Gly
                1370                1375                1380

 Gly Gly Arg Ser Gly Met Phe Cys Ala Ile Gly Ile Val Val Glu
                1385                1390                1395

 Met Val Lys Arg Gln Asn Val Val Asp Val Phe His Ala Val Lys
                1400                1405                1410

 Thr Leu Arg Asn Ser Lys Pro Asn Met Val Glu Ala Pro Glu Gln
                1415                1420                1425

 Tyr Arg Phe Cys Tyr Asp Val Ala Leu Glu Tyr Leu Glu Ser Ser
                1430                1435                1440

<210> 781
<211> 4565
<212> DNA
<213> Homo sapien

<400> 781
 ggcgagctaa gccggaggat gtgcagctgc ggcggcggcg ccggctacga 50

 agaggacggg gacaggcgcc gtgcgaaccg agcccagcca gccggaggac 100

 gcgggcaggg cgggacggga gcccggactc gtctgccgcc gccgtcgtcg 150

 ccgtcgtgcc ggccccgcgt ccccgcgcgc gagcgggagg agccgccgcc 200

 acctcgcgcc cgagccgccg ctagcgcgcg ccgggcatgg tcccctctta 250

 aaggcgcagg ccgcggcggc gggggcgggc gtgcggaaca aagcgccggc 300

 gcggggcctg cgggcggctc gggggccgcg atgggcgcgg cgggcccgcg 350

 gcggcggcgg cgctgcccgg gccgggcctc gcggcgctag ggcgggctgg 400

 cctccgcggg cgggggcagc gggctgaggg cgcgcggggc ctgcggcggc 450

 ggcggcggcg gcggcggcgg cccggcgggc ggagcggcgc gggcatggcc 500

 gcgcgcggcc ggcgcgcctg gctcagcgtg ctgctcgggc tcgtcctggg 550

 cttcgtgctg gcctcgcggc tcgtcctgcc ccgggcttcc gagctgaagc 600

 gagcgggccc acggcgccgc gccagccccg agggctgccg gtccgggcag 650

 gcggcggctt cccaggccgg cggggcgcgc ggcgatgcgc gcggggcgca 700

 gctctggccg cccggctcgg acccagatgg cggcccgcgc gacaggaact 750

 ttctcttcgt gggagtcatg accgcccaga aatacctgca gactcgggcc 800

 gtggccgcct acagaacatg gtccaagaca attcctggga aagttcagtt 850

 cttctcaagt gagggttctg acacatctgt accaattcca gtagtgccac 900

 tacggggtgt ggacgactcc tacccgcccc agaagaagtc cttcatgatg 950

 ctcaagtaca tgcacgacca ctacttggac aagtatgaat ggtttatgag 1000

 agcagatgat gacgtgtaca tcaaaggaga ccgtctggag aacttcctga 1050

 ggagtttgaa cagcagcgag cccctctttc ttgggcagac aggcctgggc 1100

 accacggaag aaatgggaaa actggccctg gagcctggtg agaacttctg 1150

 catggggggg cctggcgtga tcatgagccg ggaggtgctt cggagaatgg 1200

 tgccgcacat tggcaagtgt ctccgggaga tgtacaccac ccatgaggac 1250

 gtggaggtgg gaaggtgtgt ccggaggttt gcaggggtgc agtgtgtctg 1300

 gtcttatgag atgcagcagc ttttttatga gaattacgag cagaacaaaa 1350

 aggggtacat tagagatctc cataacagta aaattcacca agctatcaca 1400

 ttacacccca acaaaaaccc accctaccag tacaggctcc acagctacat 1450

 gctgagccgc aagatatccg agctccgcca tcgcacaata cagctgcacc 1500

 gcgaaattgt cctgatgagc aaatacagca acacagaaat tcataaagag 1550

 gacctccagc tgggaatccc tccctccttc atgaggtttc agccccgcca 1600

 gcgagaggag attctggaat gggagtttct gactggaaaa tacttgtatt 1650

 cggcagttga cggccagccc cctcgaagag gaatggactc cgcccagagg 1700

 gaagccttgg acgacattgt catgcaggtc atggagatga tcaatgccaa 1750

 cgccaagacc agagggcgca tcattgactt caaagagatc cagtacggct 1800

 accgccgggt gaaccccatg tatggggctg agtacatcct ggacctgctg 1850

 cttctgtaca aaaagcacaa agggaagaaa atgacggtcc ctgtgaggag 1900

 gcacgcgtat ttacagcaga ctttcagcaa aatccagttt gtggagcatg 1950

 aggagctgga tgcacaagag ttggccaaga gaatcaatca ggaatctgga 2000

 tccttgtcct ttctctcaaa ctccctgaag aagctcgtcc cctttcagct 2050

 ccctgggtcg aagagtgagc acaaagaacc caaagataaa aagataaaca 2100

 tactgattcc tttgtctggg cgtttcgaca tgtttgtgag atttatggga 2150

 aactttgaga agacgtgtct tatccccaat cagaacgtca agctcgtggt 2200

 tctgcttttc aattctgact ccaaccctga caaggccaaa caagttgaac 2250

 tgatgacaga ttaccgcatt aagtacccta aagccgacat gcagattttg 2300

 cctgtgtctg gagagttttc aagagccctg gccctggaag taggatcctc 2350

 ccagtttaac aatgaatctt tgctcttctt ctgcgacgtc gacctcgtct 2400

 ttactacaga attccttcag cgatgtcgag caaatacagt tctgggccaa 2450

 caaatatatt ttccaatcat cttcagccag tatgacccaa agattgttta 2500

 tagtgggaaa gttcccagtg acaaccattt tgcctttact cagaaaactg 2550

 gcttctggag aaactatggg tttggcatca cgtgtattta taagggagat 2600

 cttgtccgag tgggtggctt tgatgtttcc atccaaggct gggggctgga 2650

 ggatgtggac cttttcaaca aggttgtcca ggcaggtttg aagacgttta 2700

 ggagccagga agtaggagta gtccacgtcc accatcctgt cttttgtgat 2750

 cccaatcttg accccaaaca gtacaaaatg tgcttggggt ccaaagcatc 2800

 gacctatggg tccacacagc agctggctga gatgtggctg gaaaaaaatg 2850

 atccaagtta cagtaaaagc agcaataata atggctcagt gaggacagcc 2900

 taatgtccag ctttgctgga aaagacgttt ttaattatct aatttatttt 2950

 tcaaaaattt tttgtatgat cagtttttga agtccgtata caaggatata 3000

 ttttacaagt ggttttctta cataggactc ctttaagatt gagctttctg 3050

 aacaagaagg tgatcagtgt ttgcctttga acacatcttc ttgctgaaca 3100

 ttatgtagca gacctgctta actttgactt gaaatgtacc tgatgaacaa 3150

 aactttttta aaaaaatgtt ttcttttgag accctttgct ccagtcctat 3200

 ggcagaaaac gtgaacattc ctgcaaagta ttattgtaac aaaacactgt 3250

 aactctggta aatgttctgt tgtgattgtt aacattccac agattctacc 3300

 ttttgtgttt tgtttttttt tttttacaat tgttttaaag ccatttcatg 3350

 ttccagttgt aagataagga aatgtgataa tagctgtttc atcattgtct 3400

 tcaggagagc tttccagagt tgatcatttc ccctcatggt actctgctca 3450

 gcatggccac gtaggttttt tgtttgtttt gttttgttct ttttttgaga 3500

 cggagtctca ctctgttacc caggctggaa tgcagtggcg caatcttggc 3550

 tcactttaac ctccacttcc ctggttcaag caattcccct gcctttgcct 3600

 cccgagtagc tgggattaca ggcacacacc accacgccca gctagttttt 3650

 ttgtattttt agtagagacg gggtttcacc atgcaagccc agctggccac 3700

 gtaggtttta aagcaagggg cgtgaagaag gcacagtgag gtatgtggct 3750

 gttctcgtgg tagttcattc ggcctaaata gacctggcat taaatttcaa 3800

 gaaggatttg gcattttctc ttcttgaccc ttctctttaa agggtaaaat 3850

 attaatgttt agaatgacaa agatgaatta ttacaataaa tctgatgtac 3900

 acagactgaa acacacacac atacacccta atcaaaacgt tggggaaaaa 3950

 tgtatttggt tttgttcctt tcatcctgtc tgtgttatgt gggtggagat 4000

 ggttttcatt ctttcattac tgttttgttt tatcctttgt atctgaaata 4050

 cctttaattt atttaatatc tgttgttcag agctctgcca tttcttgagt 4100

 acctgttagt tagtattatt tatgtgtatc gggagtgtgt ttagtctgtt 4150

 ttatttgcag taaaccgatc tccaaagatt tccttttgga aacgcttttt 4200

 cccctcctta atttttatat tccttactgt tttactaaat attaagtgtt 4250

 ctttgacaat tttggtgctc atgtgttttg gggacaaaag tgaaatgaat 4300

 ctgtcattat accagaaagt taaattctca gatcaaatgt gccttaataa 4350

 atttgttttc atttagattt caaacagtga tagacttgcc attttaatac 4400

 acgtcattgg agggctgcgt atttgtaaat agcctgatgc tcatttggaa 4450

 aaataaacca gtgaacaata tttttctatt gtacttttca gaaccatttt 4500

 gtctcattat tcctgtttta gctgaagaat tgtattacat ttggagagta 4550

 aaaaacttaa acacg 4565

<210> 782
<211> 802
<212> PRT
<213> Homo sapien

<400> 782
 Met Ala Ala Arg Gly Arg Arg Ala Trp Leu Ser Val Leu Leu Gly
   1               5                  10                  15

 Leu Val Leu Gly Phe Val Leu Ala Ser Arg Leu Val Leu Pro Arg
                  20                  25                  30

 Ala Ser Glu Leu Lys Arg Ala Gly Pro Arg Arg Arg Ala Ser Pro
                  35                  40                  45

 Glu Gly Cys Arg Ser Gly Gln Ala Ala Ala Ser Gln Ala Gly Gly
                  50                  55                  60

 Ala Arg Gly Asp Ala Arg Gly Ala Gln Leu Trp Pro Pro Gly Ser
                  65                  70                  75

 Asp Pro Asp Gly Gly Pro Arg Asp Arg Asn Phe Leu Phe Val Gly
                  80                  85                  90

 Val Met Thr Ala Gln Lys Tyr Leu Gln Thr Arg Ala Val Ala Ala
                  95                 100                 105

 Tyr Arg Thr Trp Ser Lys Thr Ile Pro Gly Lys Val Gln Phe Phe
                 110                 115                 120

 Ser Ser Glu Gly Ser Asp Thr Ser Val Pro Ile Pro Val Val Pro
                 125                 130                 135

 Leu Arg Gly Val Asp Asp Ser Tyr Pro Pro Gln Lys Lys Ser Phe
                 140                 145                 150

 Met Met Leu Lys Tyr Met His Asp His Tyr Leu Asp Lys Tyr Glu
                 155                 160                 165

 Trp Phe Met Arg Ala Asp Asp Asp Val Tyr Ile Lys Gly Asp Arg
                 170                 175                 180

 Leu Glu Asn Phe Leu Arg Ser Leu Asn Ser Ser Glu Pro Leu Phe
                 185                 190                 195

 Leu Gly Gln Thr Gly Leu Gly Thr Thr Glu Glu Met Gly Lys Leu
                 200                 205                 210

 Ala Leu Glu Pro Gly Glu Asn Phe Cys Met Gly Gly Pro Gly Val
                 215                 220                 225

 Ile Met Ser Arg Glu Val Leu Arg Arg Met Val Pro His Ile Gly
                 230                 235                 240

 Lys Cys Leu Arg Glu Met Tyr Thr Thr His Glu Asp Val Glu Val
                 245                 250                 255

 Gly Arg Cys Val Arg Arg Phe Ala Gly Val Gln Cys Val Trp Ser
                 260                 265                 270

 Tyr Glu Met Gln Gln Leu Phe Tyr Glu Asn Tyr Glu Gln Asn Lys
                 275                 280                 285

 Lys Gly Tyr Ile Arg Asp Leu His Asn Ser Lys Ile His Gln Ala
                 290                 295                 300

 Ile Thr Leu His Pro Asn Lys Asn Pro Pro Tyr Gln Tyr Arg Leu
                 305                 310                 315

 His Ser Tyr Met Leu Ser Arg Lys Ile Ser Glu Leu Arg His Arg
                 320                 325                 330

 Thr Ile Gln Leu His Arg Glu Ile Val Leu Met Ser Lys Tyr Ser
                 335                 340                 345

 Asn Thr Glu Ile His Lys Glu Asp Leu Gln Leu Gly Ile Pro Pro
                 350                 355                 360

 Ser Phe Met Arg Phe Gln Pro Arg Gln Arg Glu Glu Ile Leu Glu
                 365                 370                 375

 Trp Glu Phe Leu Thr Gly Lys Tyr Leu Tyr Ser Ala Val Asp Gly
                 380                 385                 390

 Gln Pro Pro Arg Arg Gly Met Asp Ser Ala Gln Arg Glu Ala Leu
                 395                 400                 405

 Asp Asp Ile Val Met Gln Val Met Glu Met Ile Asn Ala Asn Ala
                 410                 415                 420

 Lys Thr Arg Gly Arg Ile Ile Asp Phe Lys Glu Ile Gln Tyr Gly
                 425                 430                 435

 Tyr Arg Arg Val Asn Pro Met Tyr Gly Ala Glu Tyr Ile Leu Asp
                 440                 445                 450

 Leu Leu Leu Leu Tyr Lys Lys His Lys Gly Lys Lys Met Thr Val
                 455                 460                 465

 Pro Val Arg Arg His Ala Tyr Leu Gln Gln Thr Phe Ser Lys Ile
                 470                 475                 480

 Gln Phe Val Glu His Glu Glu Leu Asp Ala Gln Glu Leu Ala Lys
                 485                 490                 495

 Arg Ile Asn Gln Glu Ser Gly Ser Leu Ser Phe Leu Ser Asn Ser
                 500                 505                 510

 Leu Lys Lys Leu Val Pro Phe Gln Leu Pro Gly Ser Lys Ser Glu
                 515                 520                 525

 His Lys Glu Pro Lys Asp Lys Lys Ile Asn Ile Leu Ile Pro Leu
                 530                 535                 540

 Ser Gly Arg Phe Asp Met Phe Val Arg Phe Met Gly Asn Phe Glu
                 545                 550                 555

 Lys Thr Cys Leu Ile Pro Asn Gln Asn Val Lys Leu Val Val Leu
                 560                 565                 570

 Leu Phe Asn Ser Asp Ser Asn Pro Asp Lys Ala Lys Gln Val Glu
                 575                 580                 585

 Leu Met Thr Asp Tyr Arg Ile Lys Tyr Pro Lys Ala Asp Met Gln
                 590                 595                 600

 Ile Leu Pro Val Ser Gly Glu Phe Ser Arg Ala Leu Ala Leu Glu
                 605                 610                 615

 Val Gly Ser Ser Gln Phe Asn Asn Glu Ser Leu Leu Phe Phe Cys
                 620                 625                 630

 Asp Val Asp Leu Val Phe Thr Thr Glu Phe Leu Gln Arg Cys Arg
                 635                 640                 645

 Ala Asn Thr Val Leu Gly Gln Gln Ile Tyr Phe Pro Ile Ile Phe
                 650                 655                 660

 Ser Gln Tyr Asp Pro Lys Ile Val Tyr Ser Gly Lys Val Pro Ser
                 665                 670                 675

 Asp Asn His Phe Ala Phe Thr Gln Lys Thr Gly Phe Trp Arg Asn
                 680                 685                 690

 Tyr Gly Phe Gly Ile Thr Cys Ile Tyr Lys Gly Asp Leu Val Arg
                 695                 700                 705

 Val Gly Gly Phe Asp Val Ser Ile Gln Gly Trp Gly Leu Glu Asp
                 710                 715                 720

 Val Asp Leu Phe Asn Lys Val Val Gln Ala Gly Leu Lys Thr Phe
                 725                 730                 735

 Arg Ser Gln Glu Val Gly Val Val His Val His His Pro Val Phe
                 740                 745                 750

 Cys Asp Pro Asn Leu Asp Pro Lys Gln Tyr Lys Met Cys Leu Gly
                 755                 760                 765

 Ser Lys Ala Ser Thr Tyr Gly Ser Thr Gln Gln Leu Ala Glu Met
                 770                 775                 780

 Trp Leu Glu Lys Asn Asp Pro Ser Tyr Ser Lys Ser Ser Asn Asn
                 785                 790                 795

 Asn Gly Ser Val Arg Thr Ala
                 800

<210> 783
<211> 4221
<212> DNA
<213> Homo sapien

<400> 783
 cagcccgagc ccgagcccga gcccgagccg gcgccaccgc gcccccggcc 50

 atggcttttg ccaatttccg ccgcatcctg cgcctgtcta ccttcgagaa 100

 gagaaagtcc cgcgaatatg agcacgtccg ccgcgacctg gaccccaacg 150

 aggtgtggga gatcgtgggc gagctgggcg acggcgcctt cggcaaggtt 200

 tacaaggcca agaataagga gacgggtgct ttggctgcgg ccaaagtcat 250

 tgaaaccaag agtgaggagg agctggagga ctacatcgtg gagattgaga 300

 tcctggccac ctgcgaccac ccctacattg tgaagctcct gggagcctac 350

 tatcacgacg ggaagctgtg gatcatgatt gagttctgtc cagggggagc 400

 cgtggacgcc atcatgctgg agctggacag aggcctcacg gagccccaga 450

 tacaggtggt ttgccgccag atgctagaag ccctcaactt cctgcacagc 500

 aagaggatca tccaccgaga tctgaaagct ggcaacgtgc tgatgaccct 550

 cgagggagac atcaggctgg ctgactttgg tgtgtctgcc aagaatctga 600

 agactctaca gaaacgagat tccttcatcg gcacgcctta ctggatggcc 650

 cccgaggtgg tcatgtgtga gaccatgaaa gacacgccct acgactacaa 700

 agccgacatc tggtccctgg gcatcacgct gattgagatg gcccagatcg 750

 agccgccaca ccacgagctc aaccccatgc gggtcctgct aaagatcgcc 800

 aagtcagacc ctcccacgct gctcacgccc tccaagtggt ctgtagagtt 850

 ccgtgacttc ctgaagatag ccctggataa gaacccagaa acccgaccca 900

 gtgccgcgca gctgctggag catcccttcg tcagcagcat caccagtaac 950

 aaggctctgc gggagctggt ggctgaggcc aaggccgagg tgatggaaga 1000

 gatcgaagac ggccgggatg agggggaaga ggaggacgcc gtggatgccg 1050

 cctccaccct ggagaaccat actcagaact cctctgaggt gagtccgcca 1100

 agcctcaatg ctgacaagcc tctcgaggag tcaccttcca ccccgctggc 1150

 acccagccag tctcaggaca gtgtgaatga gccctgcagc cagccctctg 1200

 gggacagatc cctccaaacc accagtcccc cagtcgtggc ccctggaaat 1250

 gagaacggcc tggcagtgcc tgtgcccctg cggaagtccc gacccgtgtc 1300

 aatggatgcc agaattcagg tagcccagga gaagcaagtt gctgagcagg 1350

 gtggggacct cagcccagca gccaacagat ctcaaaaggc cagccagagc 1400

 cggcccaaca gcagcgccct ggagaccttg ggtggggaga agctggccaa 1450

 tggcagcctg gagccacctg cccaggcagc tccagggcct tccaagaggg 1500

 actcggactg cagcagcctc tgcacctctg agagcatgga ctatggtacc 1550

 aatctctcca ctgacctgtc gctgaacaaa gagatgggct ctctgtccat 1600

 caaggacccg aaactgtaca aaaaaaccct caagcggaca cgcaaatttg 1650

 tggtggatgg tgtggaggtg agcatcacca cctccaagat catcagcgaa 1700

 gatgagaaga aggatgagga gatgagattt ctcaggcgcc aggaactccg 1750

 agagcttcgg ctgctccaga aagaagagca tcggaaccag acccagctga 1800

 gtaacaagca tgagctgcag ctggagcaaa tgcataaacg ttttgaacag 1850

 gaaatcaacg ccaagaagaa gttctttgac acggaattag agaacctgga 1900

 gcgtcagcaa aagcagcaag tggagaagat ggagcaagac catgccgtgc 1950

 gccgccggga ggaggccagg cggatccgcc tggagcagga tcgggactac 2000

 accaggttcc aagagcagct caaactgatg aagaaagagg tgaagaacga 2050

 ggtggagaag ctcccccgac agcagcggaa ggaaagcatg aagcagaaga 2100

 tggaggagca cacgcagaaa aagcagcttc ttgaccggga ctttgtagcc 2150

 aagcagaagg aggacctgga gctggccatg aagaggctca ccaccgacaa 2200

 caggcgggag atctgtgaca aggagcgcga gtgcctcatg aagaagcagg 2250

 agctccttcg agaccgggaa gcagccctgt gggagatgga agagcaccag 2300

 ctgcaggaga ggcaccagct ggtgaagcag cagctcaaag accagtactt 2350

 cctccagcgg cacgagctgc tgcgcaagca tgagaaggag cgggagcaga 2400

 tgcagcgcta caaccagcgc atgatagagc agctgaaggt gcggcagcaa 2450

 caggaaaagg cgcggctgcc caagatccag aggagtgagg gcaagacgcg 2500

 catggccatg tacaagaaga gcctccacat caacggcggg ggcagcgcag 2550

 ctgagcagcg tgagaagatc aagcagttct cccagcagga ggagaagagg 2600

 cagaagtcgg agcggctgca gcaacagcag aaacacgaga accagatgcg 2650

 ggacatgctg gcgcagtgtg agagcaacat gagcgagctg cagcagctgc 2700

 agaatgaaaa gtgccacctc ctggtagagc acgaaaccca gaaactgaag 2750

 gccctggatg agagccataa ccagaacctg aaggaatggc gggacaagct 2800

 tcggccgcgc aagaaggctc tggaagagga tctgaaccag aagaagcggg 2850

 agcaggagat gttcttcaag ctgagcgagg aggcggagtg cccaaacccc 2900

 tccaccccaa gcaaggccgc caagttcttc ccctacagtt ctgcggatgc 2950

 ttcttaacaa ccgcccgggg ctgtggctgg cagcttggtg ggccccaggg 3000

 ccttctcctt cattctctgt gaacatgtaa ctcaggaccc cttttccctc 3050

 ttgcgtctgt gccagctcaa atccagcccc tcgccctgtg ccaccccaac 3100

 tgtgcctgat agacctgccc cagcgttcct gacttcttgc tggcctgtgg 3150

 agggtgaggt gtaattattt gtcacctgaa cctaatgtat attctccttg 3200

 agccccagat cccttcaagc tggaagggat ggggctgttg gtggggtcag 3250

 ggtccaagag gaatgggtgt tctgtggcct cgagtcctct cctgtttgcg 3300

 aaaataccag ttttgctctc tgtgggacaa agcactgctg atgaagtccc 3350

 cgtgggctca tccgggctgg aattcttggt ttttcagcca ttccctgcag 3400

 agtcactcaa tcatcaagtc cctcacagcc atttctgttc ccagaggagc 3450

 caggcctgca gctggctgct caggagatgg cctcattcct cctgttctcc 3500

 cagtttgctt tccacttaag acaaagcctt gtctatgtgg ggggcgggga 3550

 ccggggaaag agggaggctg aaatgtttat tctgcttctc ccgtgtttca 3600

 tgccatctcg cgtccccctt cctgcacatg ggtgtgaatg cacacacata 3650

 cgcgtacaca caggacttgg tctgctggcc tggcctcttc tgcccaggtg 3700

 ggttggaaca cgtttgctgc ctgagcctgt gccactgagc atgttaggtg 3750

 gagcagttgg tgtggcacgt gcggggtgtt ggcaccggag gcatggaaaa 3800

 gcacaggctg tactgccagg ctgcgatgcg tgctggcccc cgcacaggct 3850

 cctgtgtgca gggactgatt cctcagcaca cgaggcttcc acaacccagt 3900

 ctgctccata gcactctggc ccaccctgtc tgcaggtgaa acaggagggc 3950

 tgtttgcctc tgccccatcc ccccgactgt gttcaggagt cccaccttgc 4000

 atttcagacc tgggctggca gtctgttgga cttctcttca ggaagaaaaa 4050

 gcatcagggg gaaatggaat gcccctgccc caggaacatg gcagaagcac 4100

 aggttctgta cctcagatgg actcctgctg ggccttcggg gtctcagttg 4150

 gcttccccca gattctgatt ctacagctgc agaatgtata taacacaata 4200

 aaagcaaatg tttgaaccag t 4221

<210> 784
<211> 968
<212> PRT
<213> Homo sapien

<400> 784
 Met Ala Phe Ala Asn Phe Arg Arg Ile Leu Arg Leu Ser Thr Phe
   1               5                  10                  15

 Glu Lys Arg Lys Ser Arg Glu Tyr Glu His Val Arg Arg Asp Leu
                  20                  25                  30

 Asp Pro Asn Glu Val Trp Glu Ile Val Gly Glu Leu Gly Asp Gly
                  35                  40                  45

 Ala Phe Gly Lys Val Tyr Lys Ala Lys Asn Lys Glu Thr Gly Ala
                  50                  55                  60

 Leu Ala Ala Ala Lys Val Ile Glu Thr Lys Ser Glu Glu Glu Leu
                  65                  70                  75

 Glu Asp Tyr Ile Val Glu Ile Glu Ile Leu Ala Thr Cys Asp His
                  80                  85                  90

 Pro Tyr Ile Val Lys Leu Leu Gly Ala Tyr Tyr His Asp Gly Lys
                  95                 100                 105

 Leu Trp Ile Met Ile Glu Phe Cys Pro Gly Gly Ala Val Asp Ala
                 110                 115                 120

 Ile Met Leu Glu Leu Asp Arg Gly Leu Thr Glu Pro Gln Ile Gln
                 125                 130                 135

 Val Val Cys Arg Gln Met Leu Glu Ala Leu Asn Phe Leu His Ser
                 140                 145                 150

 Lys Arg Ile Ile His Arg Asp Leu Lys Ala Gly Asn Val Leu Met
                 155                 160                 165

 Thr Leu Glu Gly Asp Ile Arg Leu Ala Asp Phe Gly Val Ser Ala
                 170                 175                 180

 Lys Asn Leu Lys Thr Leu Gln Lys Arg Asp Ser Phe Ile Gly Thr
                 185                 190                 195

 Pro Tyr Trp Met Ala Pro Glu Val Val Met Cys Glu Thr Met Lys
                 200                 205                 210

 Asp Thr Pro Tyr Asp Tyr Lys Ala Asp Ile Trp Ser Leu Gly Ile
                 215                 220                 225

 Thr Leu Ile Glu Met Ala Gln Ile Glu Pro Pro His His Glu Leu
                 230                 235                 240

 Asn Pro Met Arg Val Leu Leu Lys Ile Ala Lys Ser Asp Pro Pro
                 245                 250                 255

 Thr Leu Leu Thr Pro Ser Lys Trp Ser Val Glu Phe Arg Asp Phe
                 260                 265                 270

 Leu Lys Ile Ala Leu Asp Lys Asn Pro Glu Thr Arg Pro Ser Ala
                 275                 280                 285

 Ala Gln Leu Leu Glu His Pro Phe Val Ser Ser Ile Thr Ser Asn
                 290                 295                 300

 Lys Ala Leu Arg Glu Leu Val Ala Glu Ala Lys Ala Glu Val Met
                 305                 310                 315

 Glu Glu Ile Glu Asp Gly Arg Asp Glu Gly Glu Glu Glu Asp Ala
                 320                 325                 330

 Val Asp Ala Ala Ser Thr Leu Glu Asn His Thr Gln Asn Ser Ser
                 335                 340                 345

 Glu Val Ser Pro Pro Ser Leu Asn Ala Asp Lys Pro Leu Glu Glu
                 350                 355                 360

 Ser Pro Ser Thr Pro Leu Ala Pro Ser Gln Ser Gln Asp Ser Val
                 365                 370                 375

 Asn Glu Pro Cys Ser Gln Pro Ser Gly Asp Arg Ser Leu Gln Thr
                 380                 385                 390

 Thr Ser Pro Pro Val Val Ala Pro Gly Asn Glu Asn Gly Leu Ala
                 395                 400                 405

 Val Pro Val Pro Leu Arg Lys Ser Arg Pro Val Ser Met Asp Ala
                 410                 415                 420

 Arg Ile Gln Val Ala Gln Glu Lys Gln Val Ala Glu Gln Gly Gly
                 425                 430                 435

 Asp Leu Ser Pro Ala Ala Asn Arg Ser Gln Lys Ala Ser Gln Ser
                 440                 445                 450

 Arg Pro Asn Ser Ser Ala Leu Glu Thr Leu Gly Gly Glu Lys Leu
                 455                 460                 465

 Ala Asn Gly Ser Leu Glu Pro Pro Ala Gln Ala Ala Pro Gly Pro
                 470                 475                 480

 Ser Lys Arg Asp Ser Asp Cys Ser Ser Leu Cys Thr Ser Glu Ser
                 485                 490                 495

 Met Asp Tyr Gly Thr Asn Leu Ser Thr Asp Leu Ser Leu Asn Lys
                 500                 505                 510

 Glu Met Gly Ser Leu Ser Ile Lys Asp Pro Lys Leu Tyr Lys Lys
                 515                 520                 525

 Thr Leu Lys Arg Thr Arg Lys Phe Val Val Asp Gly Val Glu Val
                 530                 535                 540

 Ser Ile Thr Thr Ser Lys Ile Ile Ser Glu Asp Glu Lys Lys Asp
                 545                 550                 555

 Glu Glu Met Arg Phe Leu Arg Arg Gln Glu Leu Arg Glu Leu Arg
                 560                 565                 570

 Leu Leu Gln Lys Glu Glu His Arg Asn Gln Thr Gln Leu Ser Asn
                 575                 580                 585

 Lys His Glu Leu Gln Leu Glu Gln Met His Lys Arg Phe Glu Gln
                 590                 595                 600

 Glu Ile Asn Ala Lys Lys Lys Phe Phe Asp Thr Glu Leu Glu Asn
                 605                 610                 615

 Leu Glu Arg Gln Gln Lys Gln Gln Val Glu Lys Met Glu Gln Asp
                 620                 625                 630

 His Ala Val Arg Arg Arg Glu Glu Ala Arg Arg Ile Arg Leu Glu
                 635                 640                 645

 Gln Asp Arg Asp Tyr Thr Arg Phe Gln Glu Gln Leu Lys Leu Met
                 650                 655                 660

 Lys Lys Glu Val Lys Asn Glu Val Glu Lys Leu Pro Arg Gln Gln
                 665                 670                 675

 Arg Lys Glu Ser Met Lys Gln Lys Met Glu Glu His Thr Gln Lys
                 680                 685                 690

 Lys Gln Leu Leu Asp Arg Asp Phe Val Ala Lys Gln Lys Glu Asp
                 695                 700                 705

 Leu Glu Leu Ala Met Lys Arg Leu Thr Thr Asp Asn Arg Arg Glu
                 710                 715                 720

 Ile Cys Asp Lys Glu Arg Glu Cys Leu Met Lys Lys Gln Glu Leu
                 725                 730                 735

 Leu Arg Asp Arg Glu Ala Ala Leu Trp Glu Met Glu Glu His Gln
                 740                 745                 750

 Leu Gln Glu Arg His Gln Leu Val Lys Gln Gln Leu Lys Asp Gln
                 755                 760                 765

 Tyr Phe Leu Gln Arg His Glu Leu Leu Arg Lys His Glu Lys Glu
                 770                 775                 780

 Arg Glu Gln Met Gln Arg Tyr Asn Gln Arg Met Ile Glu Gln Leu
                 785                 790                 795

 Lys Val Arg Gln Gln Gln Glu Lys Ala Arg Leu Pro Lys Ile Gln
                 800                 805                 810

 Arg Ser Glu Gly Lys Thr Arg Met Ala Met Tyr Lys Lys Ser Leu
                 815                 820                 825

 His Ile Asn Gly Gly Gly Ser Ala Ala Glu Gln Arg Glu Lys Ile
                 830                 835                 840

 Lys Gln Phe Ser Gln Gln Glu Glu Lys Arg Gln Lys Ser Glu Arg
                 845                 850                 855

 Leu Gln Gln Gln Gln Lys His Glu Asn Gln Met Arg Asp Met Leu
                 860                 865                 870

 Ala Gln Cys Glu Ser Asn Met Ser Glu Leu Gln Gln Leu Gln Asn
                 875                 880                 885

 Glu Lys Cys His Leu Leu Val Glu His Glu Thr Gln Lys Leu Lys
                 890                 895                 900

 Ala Leu Asp Glu Ser His Asn Gln Asn Leu Lys Glu Trp Arg Asp
                 905                 910                 915

 Lys Leu Arg Pro Arg Lys Lys Ala Leu Glu Glu Asp Leu Asn Gln
                 920                 925                 930

 Lys Lys Arg Glu Gln Glu Met Phe Phe Lys Leu Ser Glu Glu Ala
                 935                 940                 945

 Glu Cys Pro Asn Pro Ser Thr Pro Ser Lys Ala Ala Lys Phe Phe
                 950                 955                 960

 Pro Tyr Ser Ser Ala Asp Ala Ser
                 965

<210> 785
<211> 6450
<212> DNA
<213> Homo sapien

<400> 785
 cgcgctcgcg gggggcggtg gcgcccggca cagaggggtt aagggggcgg 50

 tgcagacgtc tccccgccca tcccgcccct cgagagccgc ggcgccccgc 100

 cctatttata gcagcggtgc ctagcgcgcc gcgtctctcc gcaggccccg 150

 gccgcggcgt cctcgacaac ctatcgaagg cgccatggag cgaccggcgc 200

 ccctggccgt gcttcccttc tcggaccccg cgcacgccct gagcctgctg 250

 cgcggcctga gccagctgcg cgccgagcgc aagttcctgg acgtgaccct 300

 ggaggcggcg ggcgggcgcg acttcccggc gcaccgtgcg gtgctggccg 350

 ccgccagccc ctacttccgc gccatgttcg cggggcagct gcgcgagagc 400

 cgcgccgagc gggtgcgcct gcacggagtg cctcccgaca tgctgcagct 450

 gctgctggac ttcagctaca cgggccgcgt ggcggtaagc ggcgacaacg 500

 ctgagccgct gctgcgcgcc gccgacctgc tgcagttccc ggccgtgaag 550

 gaggcgtgcg gggccttcct gcagcagcag ctcgacctgg ccaactgcct 600

 ggacatgcag gacttcgctg aggccttcag ctgctcggga ctggcgagcg 650

 cggcgcagcg gttcattctg cgccacgtgg gcgagctggg cgccgagcag 700

 ctggagcggc tgccactggc gcgcctgctg cgctacctgc gggacgacgg 750

 gctgtgtgtg cccaaggagg aggccgccta ccagctggcg ctgcgctggg 800

 tccgcgctga cccgccgcgc cgcgccgcgc actggccgca gctgctggag 850

 gccgtgcgcc tgcccttcgt gcgccgcttc tacctgttgg cgcacgtcga 900

 ggccgagccg ctggtggcgc gctgcccacc ctgcctgcgc ctgctgcgcg 950

 aggcgcgcga cttccaggcg gcgcgctacg accgccacga ccgcgggccc 1000

 tgtccccgaa tgcgtcctcg cccgtccacc ggtctcgccg agatcctcgt 1050

 gctcgtgggc ggctgcgacc aggactgtga cgagctggtc actgtcgact 1100

 gctacaaccc gcagacgggt cagtggcgct acctggccga gttcccagac 1150

 cacctgggcg gaggctacag catcgtggcg ctgggcaatg acatctacgt 1200

 gacgggtggg tccgatggct cccggctcta tgactgcgtg tggaggtaca 1250

 actcaagcgt gaatgagtgg gcggaggtgg cgcccatgct gaaggcccgc 1300

 gagtaccaca gctcctctgt gctggacgga ctgctgtacg tggtggccgc 1350

 cgacagcacc gagcgctatg accacaccac tgactcctgg gaggccctgc 1400

 agcccatgac ctaccccatg gacaactgct ccaccactgc gtgccgtggc 1450

 cggctctatg ccatcggctc cctggctggc aaggagacca tggtgatgca 1500

 gtgctacgac ccggacaccg acctgtggtc gctggtggac tgcggccagc 1550

 tcccgccctg gtccttcgcc cccaagactg cgactctaaa cggactcatg 1600

 tactttgtca gggatgactc cgctgaggtg gacgtgtaca acccgacgag 1650

 gaacgaatgg gacaagatcc cgtccatgaa tcaggtaaat tttcaggcgg 1700

 gccagcattg gaagcacagg ctggtcctga ttttgcaacc caagtgtcat 1750

 cgtgatgagt gtttgggatc cacagccatg atggatgggt ctcatctcaa 1800

 ttaatagaag gctgctctta cccttatttt gcacttaagg ctcactgaga 1850

 cacagatgtt aagtaatacc ctatgattac acagcttagt acacatttga 1900

 gcagtgttta ttgagtatct gctgtgagcc agagagcaga aggaagtgag 1950

 ggagcaaggc atacagtcat ctggggacac ctgttccaga gagggacagc 2000

 aggtacagag gccctgcagc agggcaccct ggcgtgttct tagatacacc 2050

 agcagcccat gtggccggag cagagtcagc atgaggtctg tgacctacct 2100

 tttttatttt tgagacaggg tcttgctctg tcacccaggc tggagtgcag 2150

 tggtacaatc atggctcact gcagcctcca cctccttgac tcgcagtcct 2200

 cccaccgcac cttcctgaat agctgagact acaggcgtgt gccaccacac 2250

 ccagtaattt tttttctcat atgtagatac aaaaggatat tcttaaaatt 2300

 tttatagaga cagggtcttg ctgtgttacc caggctggtc tcacactcct 2350

 ggcctcaagt gaccctcctg tctcagcctc ccaaagtgct aggattatag 2400

 gcgtgaacca ccacgcccag ctggttcctg aggaagtcag tgtgggaata 2450

 cttttttttt ttttatacgg agtctcgctc tgtcacccag gctggagtgc 2500

 agtggcacga tctcggctca ctgcaagctc catctcccag gttcacgcca 2550

 ttctcccgcc tcaacctccc gagtagctgg gactacaggt acccaccacc 2600

 acgcccagct aattttgttt gtgtattttt agtagagacg ggatttcact 2650

 gtgttagcca ggatggtctg gatctcctga ccttgtgatc tgcctggctc 2700

 agcctcccaa agtgctggga ttacaggcat gagccaccat gcccagccca 2750

 ctgtgggaat acttgtgttg agcacttgct gtgtgttctg aataggacaa 2800

 ccagggtcca ccccttctct ctgggcttgt tgagaagagg ggtgcccagc 2850

 ctgacagtga tgggacaggg aggcttcagt gccatttggc catgtgagca 2900

 gtgttagtct gaggtacaca tcatattgcc tacagccttc tttcctgtgt 2950

 gtctgttaac atttccaaac ctacactccg tgacatccag cctcacagct 3000

 tacatcacag cttaatgtcc tggcatttaa gagacccagc gttctgtttt 3050

 ccccgcagta agctgcacat agtcatagcg aatttgggaa agatggaagg 3100

 aatcatccag cctcgcggtt cagagcccag ctctgccact gtcagccatg 3150

 caagcctcag ttttcccatc tgtaacatgg ggagaacagc actgctcagc 3200

 ccagagggcc actgcagaga ttctgagaga gaacgtagga agcgctgctc 3250

 ggcacgacct gcacacgggg aggcctggcg ctgcagcggg caccctcatc 3300

 accataggga aggcccagct gcctccgggg aggcccgttc tcctaggcag 3350

 ggtgttggaa aggggttggc ctctctgctg ctttctggga gagccaaggc 3400

 cacccctctg gggtactgac agggcatgcc ttgtctccag tggttcccca 3450

 ggtggggccc tgccctaccc tctcctctga cctccactca ctcatccctt 3500

 tggcccacag gtacatgtgg ggggcagcct ggccgtcctt ggggggaagc 3550

 tgtacgtctc tgggggatac gacaatacat ttgaactctc ggacgtggta 3600

 gaggcctatg acccagagac tcgcgcgtgg agcgtggtgg ggcggctccc 3650

 agaacccacc ttctggcatg gcagtgtcag catcttccgc cagttcatgc 3700

 cccagacctt ctcgggtggg cgtggcttcg agttggacag tggcagcgat 3750

 gacatggacc caggccgacc ccggccgccg cgggaccccg atgagctgca 3800

 ctagccccag tctggcccgg cacgggcctc ggtgcaggta actggcacct 3850

 ctgcggggca gtgccccact cctttgtgca caaggacacg ttgggctcac 3900

 aggaggagca caggctcttg ggtggcgaag ccagcccagg atccattacc 3950

 tggaaggttt ctgtaccttg agagcctgaa tcagaggccg tcgggaacgc 4000

 cctccctgca gttgaggaag agccactttc ctgccagcac atgtttctgg 4050

 gtcttggagg tcacccccac cccgcggatc acagctcacc cacgcggcgc 4100

 acacccctcc tgccgttgtc atctgcacct acttgttccc accttgggag 4150

 aggacgatga cttgggaggg acgcgtgaag ggagaagggg tcctcccatg 4200

 aggctgagga tggcctgaac ctggagcagc ggaccaggca gacgggctga 4250

 agtggggtcc caaattccat gtccagaggt gtggggagcc tgcctcccta 4300

 gctcctggcc cctgccaggg gcttacatca aaacacctca gagggctgcc 4350

 ctccagaggc tgcacccaga acagtgggac atgagcaggg gtgtgggctt 4400

 ggagggtgaa gaggatgtgg tcctatcaga tgctgggcct cctcagccat 4450

 agccccctgc tcctaccccc tgactggctc ttgcgtcctc acctctcacc 4500

 ctctccttcc cgggaggccc tgggaggtga tcattgacac ccagccaagc 4550

 agacagctgc gggtgcccaa gcccttgctg ggcctgcgcg tgaggagtcc 4600

 cactgcttct aaaggaagtc ctgggcagga ggtggctttg gtggttggtt 4650

 ccaaagttga aaatgcttgc agtttgacct tagaagaagt gggaagaaga 4700

 aggagctcta cagggtcagc tttgtttgat ttgtccagtc taagaagtcc 4750

 cattgccaaa gctttctgca ggagggtgaa tgccgcagct tggcagcccc 4800

 tgggtttctc ttggaaatgg tcagtttccc ctcaaagtac ccaaagtagc 4850

 cttggcttga gtttttgtcc ttgcctcctt tttagagaag agggcattta 4900

 gactgcattt tcctggttaa agaaggttaa agcaaatgtt tattgccttt 4950

 tctagtgaac taactcgtag agatgttctc agcaggaaga cagtcttagc 5000

 actgtcactt agcagattgc acttaagtcc cttgtgctgg ccagatggcg 5050

 tggctggttg ccttaatatg tcccaggacc cctgacaggg ctgcctggcc 5100

 tctccctcgt gctcctcaag agcccagtcc atacactgtg gatgtcattg 5150

 ctgtcgggtt aggaagtctt gtcctagaac gccctggctg gtatgaccac 5200

 agttcatggc ggctcttctc gcttgggtca tggtcatctt ccagcacctg 5250

 ctgtgctggg aaggccgagg atgggggccc agcactgtcc aggcctgctg 5300

 gggcctggct gggagtcctg tgggcagcat ggaacatgca gctgggcttc 5350

 ctgtgaccag gcaccctctg gcactgttgc ttgccctgtg ccctggacct 5400

 tttcctgccc ttctccttcc tctgctccct tggggctacc ccttggcccc 5450

 tcctggtctg tgcaaactcc ctcagggagc ccccctgccc tgtagctctc 5500

 gcttaacttc ctaggggctg ctgagcccac ccagaggttg ttggagttca 5550

 gcggggcagc ttgtctccct tgtcagcagg ggcgtaaggg ctgggtttgg 5600

 ccatacaagg ttggctacgc cctcaatccc tgaccgttcc aggcactgag 5650

 ctgggcaccc acggaaggac atgctgtcca gactgtgatg actgccagca 5700

 cagggcatct cgggcttggc tggtctgcga ggccttgccc ctgtggaact 5750

 ctgggttcct gttttctcag tcttttttgc ggctttgctg tggttggcag 5800

 ctgccgtact ccaggcttgt gtcggccact cagatgaggg ctgtggtgcg 5850

 agccagtgca ggagagctgc gcttgggatt gtgccctctc ctgtgtctgt 5900

 cctccggacc tacccaggtc tccaccatca ggaccctgtc tttgggttta 5950

 gaagaccaag tatggggaaa accaggcacc agcctctgca gcaatgggtc 6000

 cctctagcct gtggacacca gctgggggat ccagggtcag gccccctcct 6050

 ctccccagtt tccctctgct gtgggttctg ggctgtcatg tctccaccac 6100

 ttaaggatgt ctttacactg acttcaggat agatgttggg atgcctgggc 6150

 atggccacat gttacatgta cagaactttg tctacagcac aaattaagtt 6200

 atataaacac agtgactggt atttaatgct gatctactat aaggtattct 6250

 atatttatat gacttcagag acgcgtatgt aataaaggac gccctccctc 6300

 cagtgtccac atccagttca ccccagaggg tcgggcaggt tgacatattt 6350

 atttttgtct attctgtagg cttccatgtc cagaatcctg cttaaggttt 6400

 tagggtacct tcagtacttt ttgcaataaa agtatttcct atccatttgg 6450

<210> 786
<211> 539
<212> PRT
<213> Homo sapien

<400> 786
 Met Glu Arg Pro Ala Pro Leu Ala Val Leu Pro Phe Ser Asp Pro
   1               5                  10                  15

 Ala His Ala Leu Ser Leu Leu Arg Gly Leu Ser Gln Leu Arg Ala
                  20                  25                  30

 Glu Arg Lys Phe Leu Asp Val Thr Leu Glu Ala Ala Gly Gly Arg
                  35                  40                  45

 Asp Phe Pro Ala His Arg Ala Val Leu Ala Ala Ala Ser Pro Tyr
                  50                  55                  60

 Phe Arg Ala Met Phe Ala Gly Gln Leu Arg Glu Ser Arg Ala Glu
                  65                  70                  75

 Arg Val Arg Leu His Gly Val Pro Pro Asp Met Leu Gln Leu Leu
                  80                  85                  90

 Leu Asp Phe Ser Tyr Thr Gly Arg Val Ala Val Ser Gly Asp Asn
                  95                 100                 105

 Ala Glu Pro Leu Leu Arg Ala Ala Asp Leu Leu Gln Phe Pro Ala
                 110                 115                 120

 Val Lys Glu Ala Cys Gly Ala Phe Leu Gln Gln Gln Leu Asp Leu
                 125                 130                 135

 Ala Asn Cys Leu Asp Met Gln Asp Phe Ala Glu Ala Phe Ser Cys
                 140                 145                 150

 Ser Gly Leu Ala Ser Ala Ala Gln Arg Phe Ile Leu Arg His Val
                 155                 160                 165

 Gly Glu Leu Gly Ala Glu Gln Leu Glu Arg Leu Pro Leu Ala Arg
                 170                 175                 180

 Leu Leu Arg Tyr Leu Arg Asp Asp Gly Leu Cys Val Pro Lys Glu
                 185                 190                 195

 Glu Ala Ala Tyr Gln Leu Ala Leu Arg Trp Val Arg Ala Asp Pro
                 200                 205                 210

 Pro Arg Arg Ala Ala His Trp Pro Gln Leu Leu Glu Ala Val Arg
                 215                 220                 225

 Leu Pro Phe Val Arg Arg Phe Tyr Leu Leu Ala His Val Glu Ala
                 230                 235                 240

 Glu Pro Leu Val Ala Arg Cys Pro Pro Cys Leu Arg Leu Leu Arg
                 245                 250                 255

 Glu Ala Arg Asp Phe Gln Ala Ala Arg Tyr Asp Arg His Asp Arg
                 260                 265                 270

 Gly Pro Cys Pro Arg Met Arg Pro Arg Pro Ser Thr Gly Leu Ala
                 275                 280                 285

 Glu Ile Leu Val Leu Val Gly Gly Cys Asp Gln Asp Cys Asp Glu
                 290                 295                 300

 Leu Val Thr Val Asp Cys Tyr Asn Pro Gln Thr Gly Gln Trp Arg
                 305                 310                 315

 Tyr Leu Ala Glu Phe Pro Asp His Leu Gly Gly Gly Tyr Ser Ile
                 320                 325                 330

 Val Ala Leu Gly Asn Asp Ile Tyr Val Thr Gly Gly Ser Asp Gly
                 335                 340                 345

 Ser Arg Leu Tyr Asp Cys Val Trp Arg Tyr Asn Ser Ser Val Asn
                 350                 355                 360

 Glu Trp Ala Glu Val Ala Pro Met Leu Lys Ala Arg Glu Tyr His
                 365                 370                 375

 Ser Ser Ser Val Leu Asp Gly Leu Leu Tyr Val Val Ala Ala Asp
                 380                 385                 390

 Ser Thr Glu Arg Tyr Asp His Thr Thr Asp Ser Trp Glu Ala Leu
                 395                 400                 405

 Gln Pro Met Thr Tyr Pro Met Asp Asn Cys Ser Thr Thr Ala Cys
                 410                 415                 420

 Arg Gly Arg Leu Tyr Ala Ile Gly Ser Leu Ala Gly Lys Glu Thr
                 425                 430                 435

 Met Val Met Gln Cys Tyr Asp Pro Asp Thr Asp Leu Trp Ser Leu
                 440                 445                 450

 Val Asp Cys Gly Gln Leu Pro Pro Trp Ser Phe Ala Pro Lys Thr
                 455                 460                 465

 Ala Thr Leu Asn Gly Leu Met Tyr Phe Val Arg Asp Asp Ser Ala
                 470                 475                 480

 Glu Val Asp Val Tyr Asn Pro Thr Arg Asn Glu Trp Asp Lys Ile
                 485                 490                 495

 Pro Ser Met Asn Gln Val Asn Phe Gln Ala Gly Gln His Trp Lys
                 500                 505                 510

 His Arg Leu Val Leu Ile Leu Gln Pro Lys Cys His Arg Asp Glu
                 515                 520                 525

 Cys Leu Gly Ser Thr Ala Met Met Asp Gly Ser His Leu Asn
                 530                 535

<210> 787
<211> 2285
<212> DNA
<213> Homo sapien

<400> 787
 gcgcccgggc cgccggccgg gcccgggcct gggggcgggg cgggaagacg 50

 gcggccggga gtgttttcag ttccgcctcc aatcgcccat tcccctcttc 100

 ccctcccagc cccctccatc ccatcggaag aggaaggaac aaaaggtccc 150

 ggaccccccg gatctgacgg ggcgggacct ggcgccacct tgcaggttcg 200

 atacaagagg ctgttttcct agcgtggctt gctgcctttg gtaagaacat 250

 gtcgtccatc ttgccattca cgccgccagt tgtgaagaga ctgctgggat 300

 ggaagaagtc agctggtggg tctggaggag caggcggagg agagcagaat 350

 gggcaggaag aaaagtggtg tgagaaagca gtgaaaagtc tggtgaagaa 400

 gctaaagaaa acaggacgat tagatgagct tgagaaagcc atcaccactc 450

 aaaactgtaa tactaaatgt gttaccatac caagcacttg ctctgaaatt 500

 tggggactga gtacaccaaa tacgatagat cagtgggata caacaggcct 550

 ttacagcttc tctgaacaaa ccaggtctct tgatggtcgt ctccaggtat 600

 cccatcgaaa aggattgcca catgttatat attgccgatt atggcgctgg 650

 cctgatcttc acagtcatca tgaactcaag gcaattgaaa actgcgaata 700

 tgcttttaat cttaaaaagg atgaagtatg tgtaaaccct taccactatc 750

 agagagttga gacaccagtt ttgcctccag tattagtgcc ccgacacacc 800

 gagatcctaa cagaacttcc gcctctggat gactatactc actccattcc 850

 agaaaacact aacttcccag caggaattga gccacagagt aattatattc 900

 cagaaacgcc acctcctgga tatatcagtg aagatggaga aacaagtgac 950

 caacagttga atcaaagtat ggacacaggc tctccagcag aactatctcc 1000

 tactactctt tcccctgtta atcatagctt ggatttacag ccagttactt 1050

 actcagaacc tgcattttgg tgttcgatag catattatga attaaatcag 1100

 agggttggag aaaccttcca tgcatcacag ccctcactca ctgtagatgg 1150

 ctttacagac ccatcaaatt cagagaggtt ctgcttaggt ttactctcca 1200

 atgttaaccg aaatgccacg gtagaaatga caagaaggca tataggaaga 1250

 ggagtgcgct tatactacat aggtggggaa gtttttgctg agtgcctaag 1300

 tgatagtgca atctttgtgc agagccccaa ttgtaatcag agatatggct 1350

 ggcaccctgc aacagtgtgt aaaattccac caggctgtaa tctgaagatc 1400

 ttcaacaacc aggaatttgc tgctcttctg gctcagtctg ttaatcaggg 1450

 ttttgaagcc gtctatcagc taactagaat gtgcaccata agaatgagtt 1500

 ttgtgaaagg gtggggagca gaataccgaa ggcagacggt aacaagtact 1550

 ccttgctgga ttgaacttca tctgaatgga cctctacagt ggttggacaa 1600

 agtattaact cagatgggat ccccttcagt gcgttgctca agcatgtcat 1650

 aaagcttcac caatcaagtc ccatgaaaag acttaatgta acaactcttc 1700

 tgtcatagca ttgtgtgtgg tccctatgga ctgtttacta tccaaaagtt 1750

 caagagagaa aacagcactt gaggtctcat caattaaagc accttgtgga 1800

 atctgtttcc tatatttgaa tattagatgg gaaaattagt gtctagaaat 1850

 actctcccat taaagaggaa gagaagattt taaagactta atgatgtctt 1900

 attgggcata aaactgagtg tcccaaaggt ttattaataa cagtagtagt 1950

 tatgtgtaca ggtaatgtat catgatccag tatcacagta ttgtgctgtt 2000

 tatatacatt tttagtttgc atagatgagg tgtgtgtgtg cgctgcttct 2050

 tgatctaggc aaacctttat aaagttgcag tacctaatct gttattccca 2100

 cttctctgtt atttttgtgt gtctttttta atatataata tatatcaaga 2150

 ttttcaaatt atttagaagc agattttcct gtagaaaaac taatttttct 2200

 gccttttacc aaaaataaac tcttggggga agaaaaaaaa aaaaaaaaaa 2250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 2285

<210> 788
<211> 467
<212> PRT
<213> Homo sapien

<400> 788
 Met Ser Ser Ile Leu Pro Phe Thr Pro Pro Val Val Lys Arg Leu
   1               5                  10                  15

 Leu Gly Trp Lys Lys Ser Ala Gly Gly Ser Gly Gly Ala Gly Gly
                  20                  25                  30

 Gly Glu Gln Asn Gly Gln Glu Glu Lys Trp Cys Glu Lys Ala Val
                  35                  40                  45

 Lys Ser Leu Val Lys Lys Leu Lys Lys Thr Gly Arg Leu Asp Glu
                  50                  55                  60

 Leu Glu Lys Ala Ile Thr Thr Gln Asn Cys Asn Thr Lys Cys Val
                  65                  70                  75

 Thr Ile Pro Ser Thr Cys Ser Glu Ile Trp Gly Leu Ser Thr Pro
                  80                  85                  90

 Asn Thr Ile Asp Gln Trp Asp Thr Thr Gly Leu Tyr Ser Phe Ser
                  95                 100                 105

 Glu Gln Thr Arg Ser Leu Asp Gly Arg Leu Gln Val Ser His Arg
                 110                 115                 120

 Lys Gly Leu Pro His Val Ile Tyr Cys Arg Leu Trp Arg Trp Pro
                 125                 130                 135

 Asp Leu His Ser His His Glu Leu Lys Ala Ile Glu Asn Cys Glu
                 140                 145                 150

 Tyr Ala Phe Asn Leu Lys Lys Asp Glu Val Cys Val Asn Pro Tyr
                 155                 160                 165

 His Tyr Gln Arg Val Glu Thr Pro Val Leu Pro Pro Val Leu Val
                 170                 175                 180

 Pro Arg His Thr Glu Ile Leu Thr Glu Leu Pro Pro Leu Asp Asp
                 185                 190                 195

 Tyr Thr His Ser Ile Pro Glu Asn Thr Asn Phe Pro Ala Gly Ile
                 200                 205                 210

 Glu Pro Gln Ser Asn Tyr Ile Pro Glu Thr Pro Pro Pro Gly Tyr
                 215                 220                 225

 Ile Ser Glu Asp Gly Glu Thr Ser Asp Gln Gln Leu Asn Gln Ser
                 230                 235                 240

 Met Asp Thr Gly Ser Pro Ala Glu Leu Ser Pro Thr Thr Leu Ser
                 245                 250                 255

 Pro Val Asn His Ser Leu Asp Leu Gln Pro Val Thr Tyr Ser Glu
                 260                 265                 270

 Pro Ala Phe Trp Cys Ser Ile Ala Tyr Tyr Glu Leu Asn Gln Arg
                 275                 280                 285

 Val Gly Glu Thr Phe His Ala Ser Gln Pro Ser Leu Thr Val Asp
                 290                 295                 300

 Gly Phe Thr Asp Pro Ser Asn Ser Glu Arg Phe Cys Leu Gly Leu
                 305                 310                 315

 Leu Ser Asn Val Asn Arg Asn Ala Thr Val Glu Met Thr Arg Arg
                 320                 325                 330

 His Ile Gly Arg Gly Val Arg Leu Tyr Tyr Ile Gly Gly Glu Val
                 335                 340                 345

 Phe Ala Glu Cys Leu Ser Asp Ser Ala Ile Phe Val Gln Ser Pro
                 350                 355                 360

 Asn Cys Asn Gln Arg Tyr Gly Trp His Pro Ala Thr Val Cys Lys
                 365                 370                 375

 Ile Pro Pro Gly Cys Asn Leu Lys Ile Phe Asn Asn Gln Glu Phe
                 380                 385                 390

 Ala Ala Leu Leu Ala Gln Ser Val Asn Gln Gly Phe Glu Ala Val
                 395                 400                 405

 Tyr Gln Leu Thr Arg Met Cys Thr Ile Arg Met Ser Phe Val Lys
                 410                 415                 420

 Gly Trp Gly Ala Glu Tyr Arg Arg Gln Thr Val Thr Ser Thr Pro
                 425                 430                 435

 Cys Trp Ile Glu Leu His Leu Asn Gly Pro Leu Gln Trp Leu Asp
                 440                 445                 450

 Lys Val Leu Thr Gln Met Gly Ser Pro Ser Val Arg Cys Ser Ser
                 455                 460                 465

 Met Ser


<210> 789
<211> 4181
<212> DNA
<213> Homo sapien

<400> 789
 gttacttgtt attggtaaat agccactatg gaggctaagg accagaagaa 50

 acacagaaag aaaaacagtg gacccaaagc tgcaaagaaa aagaagcggc 100

 ttctgcagga tctccagcta ggagacgaag aagatgcccg gaagagaaat 150

 cccaaagctt ttgcagttca gtctgctgtg cggatggctc gatcctttca 200

 caggactcag gatttgaaga caaaaaagca tcatattcca gtggttgatc 250

 gaactccact agagccccca ccaatagtgg tagtggtgat gggacctcca 300

 aaagttggaa agagcacttt gatacaatgc ctcattcgga actttacccg 350

 gcagaagttg accgagatca gaggccctgt gacgattgtg tcaggtaaaa 400

 agcgcagact caccattatt gaatgtgggt gtgacattaa catgatgatt 450

 gatctggcta aagtagcaga tctggtactg atgcttatag atgccagctt 500

 tgggtttgaa atggaaacgt ttgagtttct aaacatctgt caagtacatg 550

 gctttcctaa aattatggga gttctcaccc acctcgactc cttcaagcat 600

 aataagcaac tgaagaagac aaagaagcga ttaaaacaca ggttctggac 650

 ggaagtttac ccgggtgcca agctgttcta cctttctgga atggtgcatg 700

 gagaatatca aaaccaagaa atccacaatc tgggccgttt tattacagtt 750

 atgaagttta ggcctctcac atggcaaact tctcaccctt atatcctggc 800

 agacaggatg gaagatttga caaacccaga ggatatccga acaaacatca 850

 aatgtgaccg gaaggtgtca ctttatggtt atttaagagg agcacacttg 900

 aaaaataaaa gccaaattca catgccaggg gtaggagatt ttgccgtgag 950

 tgacatcagt ttcctcccag acccttgcgc tcttcctgaa caacaaaaga 1000

 agcgctgttt aaatgagaag gagaagctgg tttatgcgcc tctttctgga 1050

 gttgggggtg tgctgtatga caaagacgct gtctatgttg accttggtgg 1100

 cagccacgtt tttcaggatg aagtggggcc cacccatgag ctggtccaga 1150

 gtctcatctc tacccactcc accattgatg ccaagatggc ttcaagtcga 1200

 gtgacgctgt tttctgattc caaaccactt gggtcagagg atatagataa 1250

 tcaagggcta atgatgccaa aggaggaaaa acaaatggac ttgaacactg 1300

 gtcgaatgcg tcggaaagcc attttcggag atgaagatga atctggagat 1350

 agtgatgatg aagaagatga tgaaatgtct gaagatgacg ggttggaaaa 1400

 cggctctagt gatgaggaag cagaagagga ggaaaatgct gagatgactg 1450

 atcagtatat ggctgttaag ggcatcaaac gacggaaact tgagttggaa 1500

 gaagacagtg aaatggattt gccagcattt gctgacagtg acgatgacct 1550

 tgagaggagc tcagcggaag aaggggaagc ggaggaagct gatgaaagca 1600

 gtgaagaaga ggactgcact gcaggagaga agggcatttc aggatcaaag 1650

 gctgctggag aaggtagtaa agcagggctg tcaccagcta attgccagag 1700

 tgaccgtgtg aatctggaga agtctttgct gatgaagaaa gcagctctcc 1750

 ccactttcga ttctgggcat tgcacagctg aagaggtgtt tgcatctgaa 1800

 gatgaatctg aagaaagctc ctcactcagt gcagaggaag aagactcaga 1850

 aaatgaagag gctattagaa aaaagctttc aaagccttct caagtgagca 1900

 gtggtcagaa actggggcca cagaacttca ttgatgagac cagtgatata 1950

 gaaaatttac tcaaagagga agaagattac aaggaagaaa ataatgattc 2000

 caaagaaacg tcaggtgccc tcaagtggaa ggaagacctt tccagaaagg 2050

 cagctgaggc ctttctgagg cagcagcaag cagctccaaa cctccgaaag 2100

 cttatttatg ggacagtgac agaagataat gaagaagaag atgatgatac 2150

 tctagaagag cttggagggt tgtttcgtgt caaccagcct gacagagagt 2200

 gtaagcacaa ggctgactct ttggactgct ccagatttct tgtggaggcc 2250

 ccccatgact gggatttaga ggaggttatg aacagtatca gagattgctt 2300

 cgtgactgga aagtgggaag atgataaaga tgcagccaag gtcttagcag 2350

 aagatgagga gctctacggt gactttgaag acttggaaac aggggacgtg 2400

 cacaagggaa aatcaggccc caatactcag aatgaagata tagagaaaga 2450

 agttaaggaa gaaattgacc ccgacgaaga agaaagtgcc aagaaaaagc 2500

 atttggataa gaagagaaaa ttgaaggaga tgtttgatgc agaatatgat 2550

 gaaggagaaa gcacatattt tgatgatctt aaaggagaaa tgcagaaaca 2600

 agcacagctg aatcgcgcag aatttgaaga tcaagatgat gaagccagag 2650

 ttcagtatga gggttttcga cctgggatgt acgtccgcat tgagattgaa 2700

 aatgttccct gtgaatttgt gcagaacttt gacccccatt accccattat 2750

 cctgggtggc ttgggcaaca gtgagggaaa tgttggctac gtgcagatgc 2800

 gtctgaagaa acatcgctgg tataagaaaa tcctcaagtc ccgagatcca 2850

 atcatatttt ctgtagggtg gaggaggttt cagaccatcc cactgtatta 2900

 tatcgaagac cacaatggaa gacaaaggct tctaaagtat accccacagc 2950

 acatgcattg cggagcagcc ttttggggcc ctatcactcc acagggaact 3000

 ggtttcttgg caatacagtc tgtcagtggc ataatgcctg attttcggat 3050

 agctgctaca ggagttgtcc ttgatctgga taaatccata aaaattgtga 3100

 agaaattaaa gctaactggt tttccatata aaattttcaa gaacacttca 3150

 tttattaagg gaatgtttaa ttctgccttg gaagtggcca aatttgaagg 3200

 tgctgtgatt cgaacagtca gtgggataag ggggcagatc aagaaagcac 3250

 tccgagctcc agaaggagct ttcagggcca gctttgagga taagctgctg 3300

 atgagcgata ttgtcttcat gcgaacttgg tatcctgttt ccatcccagc 3350

 gttctataac ccagtaacat ctttgttgaa accagtgggt gagaaagaca 3400

 cctggtcagg aatgcggacc acgggccaac tcaggctcgc ccatggcgtc 3450

 agactaaagg cgaacaagga ctctctgtat aagccaatcc tgaggcaaaa 3500

 gaaacatttt aattcactgc acattccaaa agccttgcag aaggccctgc 3550

 catttaagaa caagcccaag acccaagcaa aggcaggcaa ggtgccaaag 3600

 gacaggcgga gaccggccgt catacgcgag cctcatgaaa gaaagatcct 3650

 tgcactgctg gatgctctga gtacggtgca tagtcagaag atgaagaagg 3700

 ccaaggagca gcggcacctg cacaataaag agcacttcag agccaagcag 3750

 aaggaggagg aggagaagct gaagcggcag aaggacctca ggaagaagct 3800

 cttcagaatt caggggcaga aggaaagaag aaaccagaag tccagtttga 3850

 agggggctga gggccaattg cagtgagcct ttggactgga gggactgtcc 3900

 ctggatctgc ggaggtagac agtttcaaac atcacagttt gaatgcctgt 3950

 gaatgacacg tcagtgggaa agagctcaag agatgtctct actcaaactg 4000

 tgcctgcagg aggaggaaca gagaagcctg ggctgctggg actgggttca 4050

 ttctcatgac ttggggctgt cgagatttaa agtgatgtaa gctgtggtta 4100

 tgtggattct cttactttcc tctgcctgcc tcagtttaat tattttggcc 4150

 tacagaaata tcattaaaat atttttttgt t 4181

<210> 790
<211> 1282
<212> PRT
<213> Homo sapien

<400> 790
 Met Glu Ala Lys Asp Gln Lys Lys His Arg Lys Lys Asn Ser Gly
   1               5                  10                  15

 Pro Lys Ala Ala Lys Lys Lys Lys Arg Leu Leu Gln Asp Leu Gln
                  20                  25                  30

 Leu Gly Asp Glu Glu Asp Ala Arg Lys Arg Asn Pro Lys Ala Phe
                  35                  40                  45

 Ala Val Gln Ser Ala Val Arg Met Ala Arg Ser Phe His Arg Thr
                  50                  55                  60

 Gln Asp Leu Lys Thr Lys Lys His His Ile Pro Val Val Asp Arg
                  65                  70                  75

 Thr Pro Leu Glu Pro Pro Pro Ile Val Val Val Val Met Gly Pro
                  80                  85                  90

 Pro Lys Val Gly Lys Ser Thr Leu Ile Gln Cys Leu Ile Arg Asn
                  95                 100                 105

 Phe Thr Arg Gln Lys Leu Thr Glu Ile Arg Gly Pro Val Thr Ile
                 110                 115                 120

 Val Ser Gly Lys Lys Arg Arg Leu Thr Ile Ile Glu Cys Gly Cys
                 125                 130                 135

 Asp Ile Asn Met Met Ile Asp Leu Ala Lys Val Ala Asp Leu Val
                 140                 145                 150

 Leu Met Leu Ile Asp Ala Ser Phe Gly Phe Glu Met Glu Thr Phe
                 155                 160                 165

 Glu Phe Leu Asn Ile Cys Gln Val His Gly Phe Pro Lys Ile Met
                 170                 175                 180

 Gly Val Leu Thr His Leu Asp Ser Phe Lys His Asn Lys Gln Leu
                 185                 190                 195

 Lys Lys Thr Lys Lys Arg Leu Lys His Arg Phe Trp Thr Glu Val
                 200                 205                 210

 Tyr Pro Gly Ala Lys Leu Phe Tyr Leu Ser Gly Met Val His Gly
                 215                 220                 225

 Glu Tyr Gln Asn Gln Glu Ile His Asn Leu Gly Arg Phe Ile Thr
                 230                 235                 240

 Val Met Lys Phe Arg Pro Leu Thr Trp Gln Thr Ser His Pro Tyr
                 245                 250                 255

 Ile Leu Ala Asp Arg Met Glu Asp Leu Thr Asn Pro Glu Asp Ile
                 260                 265                 270

 Arg Thr Asn Ile Lys Cys Asp Arg Lys Val Ser Leu Tyr Gly Tyr
                 275                 280                 285

 Leu Arg Gly Ala His Leu Lys Asn Lys Ser Gln Ile His Met Pro
                 290                 295                 300

 Gly Val Gly Asp Phe Ala Val Ser Asp Ile Ser Phe Leu Pro Asp
                 305                 310                 315

 Pro Cys Ala Leu Pro Glu Gln Gln Lys Lys Arg Cys Leu Asn Glu
                 320                 325                 330

 Lys Glu Lys Leu Val Tyr Ala Pro Leu Ser Gly Val Gly Gly Val
                 335                 340                 345

 Leu Tyr Asp Lys Asp Ala Val Tyr Val Asp Leu Gly Gly Ser His
                 350                 355                 360

 Val Phe Gln Asp Glu Val Gly Pro Thr His Glu Leu Val Gln Ser
                 365                 370                 375

 Leu Ile Ser Thr His Ser Thr Ile Asp Ala Lys Met Ala Ser Ser
                 380                 385                 390

 Arg Val Thr Leu Phe Ser Asp Ser Lys Pro Leu Gly Ser Glu Asp
                 395                 400                 405

 Ile Asp Asn Gln Gly Leu Met Met Pro Lys Glu Glu Lys Gln Met
                 410                 415                 420

 Asp Leu Asn Thr Gly Arg Met Arg Arg Lys Ala Ile Phe Gly Asp
                 425                 430                 435

 Glu Asp Glu Ser Gly Asp Ser Asp Asp Glu Glu Asp Asp Glu Met
                 440                 445                 450

 Ser Glu Asp Asp Gly Leu Glu Asn Gly Ser Ser Asp Glu Glu Ala
                 455                 460                 465

 Glu Glu Glu Glu Asn Ala Glu Met Thr Asp Gln Tyr Met Ala Val
                 470                 475                 480

 Lys Gly Ile Lys Arg Arg Lys Leu Glu Leu Glu Glu Asp Ser Glu
                 485                 490                 495

 Met Asp Leu Pro Ala Phe Ala Asp Ser Asp Asp Asp Leu Glu Arg
                 500                 505                 510

 Ser Ser Ala Glu Glu Gly Glu Ala Glu Glu Ala Asp Glu Ser Ser
                 515                 520                 525

 Glu Glu Glu Asp Cys Thr Ala Gly Glu Lys Gly Ile Ser Gly Ser
                 530                 535                 540

 Lys Ala Ala Gly Glu Gly Ser Lys Ala Gly Leu Ser Pro Ala Asn
                 545                 550                 555

 Cys Gln Ser Asp Arg Val Asn Leu Glu Lys Ser Leu Leu Met Lys
                 560                 565                 570

 Lys Ala Ala Leu Pro Thr Phe Asp Ser Gly His Cys Thr Ala Glu
                 575                 580                 585

 Glu Val Phe Ala Ser Glu Asp Glu Ser Glu Glu Ser Ser Ser Leu
                 590                 595                 600

 Ser Ala Glu Glu Glu Asp Ser Glu Asn Glu Glu Ala Ile Arg Lys
                 605                 610                 615

 Lys Leu Ser Lys Pro Ser Gln Val Ser Ser Gly Gln Lys Leu Gly
                 620                 625                 630

 Pro Gln Asn Phe Ile Asp Glu Thr Ser Asp Ile Glu Asn Leu Leu
                 635                 640                 645

 Lys Glu Glu Glu Asp Tyr Lys Glu Glu Asn Asn Asp Ser Lys Glu
                 650                 655                 660

 Thr Ser Gly Ala Leu Lys Trp Lys Glu Asp Leu Ser Arg Lys Ala
                 665                 670                 675

 Ala Glu Ala Phe Leu Arg Gln Gln Gln Ala Ala Pro Asn Leu Arg
                 680                 685                 690

 Lys Leu Ile Tyr Gly Thr Val Thr Glu Asp Asn Glu Glu Glu Asp
                 695                 700                 705

 Asp Asp Thr Leu Glu Glu Leu Gly Gly Leu Phe Arg Val Asn Gln
                 710                 715                 720

 Pro Asp Arg Glu Cys Lys His Lys Ala Asp Ser Leu Asp Cys Ser
                 725                 730                 735

 Arg Phe Leu Val Glu Ala Pro His Asp Trp Asp Leu Glu Glu Val
                 740                 745                 750

 Met Asn Ser Ile Arg Asp Cys Phe Val Thr Gly Lys Trp Glu Asp
                 755                 760                 765

 Asp Lys Asp Ala Ala Lys Val Leu Ala Glu Asp Glu Glu Leu Tyr
                 770                 775                 780

 Gly Asp Phe Glu Asp Leu Glu Thr Gly Asp Val His Lys Gly Lys
                 785                 790                 795

 Ser Gly Pro Asn Thr Gln Asn Glu Asp Ile Glu Lys Glu Val Lys
                 800                 805                 810

 Glu Glu Ile Asp Pro Asp Glu Glu Glu Ser Ala Lys Lys Lys His
                 815                 820                 825

 Leu Asp Lys Lys Arg Lys Leu Lys Glu Met Phe Asp Ala Glu Tyr
                 830                 835                 840

 Asp Glu Gly Glu Ser Thr Tyr Phe Asp Asp Leu Lys Gly Glu Met
                 845                 850                 855

 Gln Lys Gln Ala Gln Leu Asn Arg Ala Glu Phe Glu Asp Gln Asp
                 860                 865                 870

 Asp Glu Ala Arg Val Gln Tyr Glu Gly Phe Arg Pro Gly Met Tyr
                 875                 880                 885

 Val Arg Ile Glu Ile Glu Asn Val Pro Cys Glu Phe Val Gln Asn
                 890                 895                 900

 Phe Asp Pro His Tyr Pro Ile Ile Leu Gly Gly Leu Gly Asn Ser
                 905                 910                 915

 Glu Gly Asn Val Gly Tyr Val Gln Met Arg Leu Lys Lys His Arg
                 920                 925                 930

 Trp Tyr Lys Lys Ile Leu Lys Ser Arg Asp Pro Ile Ile Phe Ser
                 935                 940                 945

 Val Gly Trp Arg Arg Phe Gln Thr Ile Pro Leu Tyr Tyr Ile Glu
                 950                 955                 960

 Asp His Asn Gly Arg Gln Arg Leu Leu Lys Tyr Thr Pro Gln His
                 965                 970                 975

 Met His Cys Gly Ala Ala Phe Trp Gly Pro Ile Thr Pro Gln Gly
                 980                 985                 990

 Thr Gly Phe Leu Ala Ile Gln Ser Val Ser Gly Ile Met Pro Asp
                 995                1000                1005

 Phe Arg Ile Ala Ala Thr Gly Val Val Leu Asp Leu Asp Lys Ser
                1010                1015                1020

 Ile Lys Ile Val Lys Lys Leu Lys Leu Thr Gly Phe Pro Tyr Lys
                1025                1030                1035

 Ile Phe Lys Asn Thr Ser Phe Ile Lys Gly Met Phe Asn Ser Ala
                1040                1045                1050

 Leu Glu Val Ala Lys Phe Glu Gly Ala Val Ile Arg Thr Val Ser
                1055                1060                1065

 Gly Ile Arg Gly Gln Ile Lys Lys Ala Leu Arg Ala Pro Glu Gly
                1070                1075                1080

 Ala Phe Arg Ala Ser Phe Glu Asp Lys Leu Leu Met Ser Asp Ile
                1085                1090                1095

 Val Phe Met Arg Thr Trp Tyr Pro Val Ser Ile Pro Ala Phe Tyr
                1100                1105                1110

 Asn Pro Val Thr Ser Leu Leu Lys Pro Val Gly Glu Lys Asp Thr
                1115                1120                1125

 Trp Ser Gly Met Arg Thr Thr Gly Gln Leu Arg Leu Ala His Gly
                1130                1135                1140

 Val Arg Leu Lys Ala Asn Lys Asp Ser Leu Tyr Lys Pro Ile Leu
                1145                1150                1155

 Arg Gln Lys Lys His Phe Asn Ser Leu His Ile Pro Lys Ala Leu
                1160                1165                1170

 Gln Lys Ala Leu Pro Phe Lys Asn Lys Pro Lys Thr Gln Ala Lys
                1175                1180                1185

 Ala Gly Lys Val Pro Lys Asp Arg Arg Arg Pro Ala Val Ile Arg
                1190                1195                1200

 Glu Pro His Glu Arg Lys Ile Leu Ala Leu Leu Asp Ala Leu Ser
                1205                1210                1215

 Thr Val His Ser Gln Lys Met Lys Lys Ala Lys Glu Gln Arg His
                1220                1225                1230

 Leu His Asn Lys Glu His Phe Arg Ala Lys Gln Lys Glu Glu Glu
                1235                1240                1245

 Glu Lys Leu Lys Arg Gln Lys Asp Leu Arg Lys Lys Leu Phe Arg
                1250                1255                1260

 Ile Gln Gly Gln Lys Glu Arg Arg Asn Gln Lys Ser Ser Leu Lys
                1265                1270                1275

 Gly Ala Glu Gly Gln Leu Gln
                1280

<210> 791
<211> 2366
<212> DNA
<213> Homo sapien

<400> 791
 caggatgtgc catatcattg aacggaacta aagtctgtga cagtggatat 50

 agctgctgga ccattccatc ttatatgtaa agaaatctgg aattattatt 100

 ttaaaaccat ataacatgtg attataattt ttcttagcat tttctttgta 150

 aagaactaca atataaacta gttggtgtat aataaaaagt aatgaaattc 200

 tgagaagagt tttatcttag gaaaatacat atatatgcag tgtgtgtgcc 250

 agtgtggtat taacaagact aatagtgcag tttgatcctt accaatatca 300

 ttacttaatt tgaagtgttc attagcaccc caaaatatac cttttctatg 350

 tactgttaaa agaaattggc ttctgatgca tgaacattta catgtacatt 400

 gaaagtagtc cataatagaa gttagtttaa gccaagtgta gacagtacat 450

 tactcccttg aaaaagaatt aagttgaaag agttgacttt gccttaaaag 500

 gcagatctaa cccaagctcc atccagtacc aaatgtgaaa cttcattgtt 550

 gtttggtgag aatcgccaaa ttctcactaa tacattggta tggtgtaggg 600

 catgctactt tttaaacagc agcacttatt tttacagatt gctactccaa 650

 ggaagaaaac tggccacttt tcatgtaaat attttgttca aagatttgta 700

 tatctctcta ggagttttcc ctcagttccc aggatggggt ccaggagtag 750

 attaacagct aaaaatctcc caaggatatc ttgttttgat ttatttactc 800

 cagggaacta tcagctcctt cacaggagcc aaaggggagc tatgaataga 850

 gggtcacatg agccagattc tttactgttc ataaaaccca gagagtagtt 900

 gtgaaagatc ctaatacaat tgtgaaaagc tctgtaaaca tgaaatctaa 950

 aacaaatgta gattttcaca atatgcttat taataaatga agtctatgga 1000

 ataagtttta gagataattt acttcagtca cctttgtttt ggaaaggact 1050

 caggttttct tgcagctgta agatatattc tatttgtgtt tatttcaaag 1100

 ggaagaggaa ggatggacaa ctgttacaat tgaccttgca aaggatattt 1150

 aaaaaaaagg tagtttttga gattaaccaa ctttcaaagg gcaataaaga 1200

 catgtgaatt tgctcatttt aaagcacaac agatgattag cttcaaattt 1250

 attatttgca ttggatgggt actgtctttg gaaagtctcc ttatagacaa 1300

 atatgctgcc ttacactatg atggcttcat tctgatcagg tattttaaaa 1350

 attagtacca gaaaagatac tggaggtaat ataatacagt ccttcagctt 1400

 tacagatagt gaaaactgaa ggccagaaaa ggaactaaaa ctcagcagtt 1450

 cataggggta gagggaaata acctgagaaa gccgagttaa atcttaaaat 1500

 ttttactata aggatagaga tgatacaagt gaactctgca aaatagtttt 1550

 gtgaaattaa acaaaaaaat ctactcttaa tgtatattat ttcatatttg 1600

 tttaacaaaa gcagcttgat gcctttgttc tggattatac attaagaaca 1650

 agcattattt taattatgta gtaacattta ctatgacttt gaagccagat 1700

 ttcaaaatct ggctttgtta aattaattgg aaacactctt ctattaagtt 1750

 aggtattaaa aaaagccaaa tatcaataaa gatattttta ttaatttttt 1800

 atagaaacaa aatagctact ataactctat tatagtatat taacagcact 1850

 tagtattata ttgacttaaa catagtagct aataaaacta gtttatgaca 1900

 tctattgaaa ttctcagtct gacagtttta aaatagctta aaactaagca 1950

 ccgggtatat gaaaaaggaa ctggaaattt taattgtcca gaaatcatag 2000

 gaatactggg aacctgtagt tacgggaaat ggctgttttt ctgaagttga 2050

 aaccagtttc aattacaaaa ccctctgaaa ttttgctaag cctatagtta 2100

 tctccctaag aaccataaaa aaagatcatt ttattgttaa tttcattcca 2150

 gtttagcttc ctcattttac atgttgggat gtcatgccct tttaatatgc 2200

 ctggcactgc acggtggcag tagcagactt gggcttaccc agaaccctaa 2250

 gtctctgacg ctataggata gcgaaagagg taggcaatcg taacagacac 2300

 tgtataggat aaatagggaa gagaatgaga gaaccaaaat aaaaataatt 2350

 taagaaacaa ttggtt 2366

<210> 792
<211> 98
<212> PRT
<213> Homo sapien

<400> 792
 Met Leu Leu Phe Lys Gln Gln His Leu Phe Leu Gln Ile Ala Thr
   1               5                  10                  15

 Pro Arg Lys Lys Thr Gly His Phe Ser Cys Lys Tyr Phe Val Gln
                  20                  25                  30

 Arg Phe Val Tyr Leu Ser Arg Ser Phe Pro Ser Val Pro Arg Met
                  35                  40                  45

 Gly Ser Arg Ser Arg Leu Thr Ala Lys Asn Leu Pro Arg Ile Ser
                  50                  55                  60

 Cys Phe Asp Leu Phe Thr Pro Gly Asn Tyr Gln Leu Leu His Arg
                  65                  70                  75

 Ser Gln Arg Gly Ala Met Asn Arg Gly Ser His Glu Pro Asp Ser
                  80                  85                  90

 Leu Leu Phe Ile Lys Pro Arg Glu
                  95

<210> 793
<211> 2905
<212> DNA
<213> Homo sapien

<400> 793
 ggccgaatac atcaagcaat ggtaacatct ttaaatgaag ataatgaaag 50

 tgtaactgtt gaatggatag aaaatggaga tacaaaaggc aaagagattg 100

 acctggagag catcttttca cttaaccctg accttgttcc tgatgaagaa 150

 attgaaccca gtccagaaac acctccacct ccagcatcct cagccaaagt 200

 aaacaaaatt gtaaagaatc gacggactgt agcttctatt aagaatgacc 250

 ctccttcaag agataataga gtggttggtt cagcacgtgc acggcccagt 300

 caatttcctg aacagtcttc ctctgcacaa cagaatggta gtgtttcaga 350

 tatatctcca gttcaagctg caaaaaagga atttggaccc ccttcacgta 400

 gaaaatctaa ttgtgtgaaa gaagtagaaa aactgcaaga aaaacgagag 450

 aaaaggagat tgcaacagca agaacttaga gaaaaaagag cccaggacgt 500

 tgatgctaca aacccaaatt atgaaattat gtgtatgatc agagacttta 550

 gaggaagttt ggattataga ccattaacaa cagcagatcc tattgatgaa 600

 cataggatat gtgtgtgtgt aagaaaacga ccactcaata aaaaagaaac 650

 tcaaatgaaa gatcttgatg taatcacaat tcctagtaaa gatgttgtga 700

 tggtacatga accaaaacaa aaagtagatt taacaaggta cctagaaaac 750

 caaacatttc gttttgatta tgcctttgat gactcagctc ctaatgaaat 800

 ggtttacagg tttactgcta aaccactagt ggaaactata tttgaaaggg 850

 gaatggctac atgctttgct tatgggcaga ctggaagtgg aaaaactcat 900

 actatgggtg gtgacttttc aggaaagaac caagattgtt ctaaaggaat 950

 ttatgcatta gcagctcgag atgtcttttt aatgctaaag aagccaaact 1000

 ataagaagct agaacttcaa gtatatgcaa ccttctttga aatttatagt 1050

 ggaaaggtgt ttgacttgct aaacaggaaa acaaaattaa gagttctaga 1100

 agatggaaaa cagcaggttc aagtggtggg attacaggaa cgggaggtca 1150

 aatgtgttga agatgtactg aaactcattg acataggcaa cagttgcaga 1200

 acatccggtc aaacatctgc aaatgcacat tcatctcgga gccatgcagt 1250

 gtttcagatt attcttagaa ggaaaggaaa actacatggc aaattttctc 1300

 tcattgattt ggctggaaat gaaagaggag ctgatacttc cagtgcggac 1350

 aggcaaacta ggcttgaagg tgctgaaatt aataaaagcc ttttagcact 1400

 caaggagtgc atcagagcct taggtagaaa taaacctcat actcctttcc 1450

 gtgcaagtaa actcactcag gtgttaagag attctttcat aggtgaaaac 1500

 tctcgtacct gcatgattgc cacaatctct ccaggaatgg catcctgtga 1550

 aaatactctt aatacattaa gatatgcaaa tagggtcaaa gaattgactg 1600

 tagatccaac tgctgctggt gatgttcgtc caataatgca ccatccacca 1650

 aaccagattg atgacttaga gacacagtgg ggtgtgggga gttcccctca 1700

 gagagatgat ctaaaacttc tttgtgaaca aaatgaagaa gaagtctctc 1750

 cacagttgtt tactttccac gaagctgttt cacaaatggt agaaatggaa 1800

 gaacaagttg tagaagatca cagggcagtg ttccaggaat ctattcggtg 1850

 gttagaagat gaaaaggccc tcttagagat gactgaagaa gtagattatg 1900

 atgtcgattc atatgctaca caacttgaag ctattcttga gcaaaaaata 1950

 gacattttaa ctgaactgcg ggataaagtg aaatctttcc gtgcagctct 2000

 acaagaggag gaacaagcca gcaagcaaat caacccgaag agaccccgtg 2050

 ccctttaaac cggcatttgc tgctaaagga tacccagaac cctcactact 2100

 gtaacataca acggttcagc tgtaagggcc atttgaaagt ttggaatttt 2150

 aagtgtctgt ggaaaatgtt ttgtccttca cctgaattac atttcaattt 2200

 tgtgaaacac tcttttgtct acaaaatgct tctagtccag gaggcacaac 2250

 caagaactgg gattaatgaa gcattttgtt tcatttacac aaatagtgat 2300

 ttacttttgg agatccttgt cagttttatt ttctatttga tgaagtaaga 2350

 ctgtggactc aatccagagc cagatagtag gggaagccac agcatttcct 2400

 tttaactcag ttcaattttt gtagtgagac tgagcagttt taaatccttt 2450

 gcgtgcatgc atacctcatc agtgattgta cataccttgc ccactcctag 2500

 agacagctgt gctcactttt cctgctttgt gccttgatta aggctactga 2550

 ccctaaattt ctgaagcaca gccaagaaaa attacattcc ttgtcattgt 2600

 aaattacctt tgtgtgtaca tttttactgt atttgagaca ttttttgtgt 2650

 gtgactagtt aattttgcag gatgtgccat atcattgaac ggaactaaag 2700

 tctgtgacag tggatatagc tgctggacca ttccatctta tatgtaaaga 2750

 aatctggaat tattatttta aaaccatata acatgtgatt ataatttttc 2800

 ttagcatttt ctttgtaaag aactacaata taaactagtt ggtgtataat 2850

 aaaaagtaat gaaattctga agaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2900

 aaaaa 2905

<210> 794
<211> 679
<212> PRT
<213> Homo sapien

<400> 794
 Met Val Thr Ser Leu Asn Glu Asp Asn Glu Ser Val Thr Val Glu
   1               5                  10                  15

 Trp Ile Glu Asn Gly Asp Thr Lys Gly Lys Glu Ile Asp Leu Glu
                  20                  25                  30

 Ser Ile Phe Ser Leu Asn Pro Asp Leu Val Pro Asp Glu Glu Ile
                  35                  40                  45

 Glu Pro Ser Pro Glu Thr Pro Pro Pro Pro Ala Ser Ser Ala Lys
                  50                  55                  60

 Val Asn Lys Ile Val Lys Asn Arg Arg Thr Val Ala Ser Ile Lys
                  65                  70                  75

 Asn Asp Pro Pro Ser Arg Asp Asn Arg Val Val Gly Ser Ala Arg
                  80                  85                  90

 Ala Arg Pro Ser Gln Phe Pro Glu Gln Ser Ser Ser Ala Gln Gln
                  95                 100                 105

 Asn Gly Ser Val Ser Asp Ile Ser Pro Val Gln Ala Ala Lys Lys
                 110                 115                 120

 Glu Phe Gly Pro Pro Ser Arg Arg Lys Ser Asn Cys Val Lys Glu
                 125                 130                 135

 Val Glu Lys Leu Gln Glu Lys Arg Glu Lys Arg Arg Leu Gln Gln
                 140                 145                 150

 Gln Glu Leu Arg Glu Lys Arg Ala Gln Asp Val Asp Ala Thr Asn
                 155                 160                 165

 Pro Asn Tyr Glu Ile Met Cys Met Ile Arg Asp Phe Arg Gly Ser
                 170                 175                 180

 Leu Asp Tyr Arg Pro Leu Thr Thr Ala Asp Pro Ile Asp Glu His
                 185                 190                 195

 Arg Ile Cys Val Cys Val Arg Lys Arg Pro Leu Asn Lys Lys Glu
                 200                 205                 210

 Thr Gln Met Lys Asp Leu Asp Val Ile Thr Ile Pro Ser Lys Asp
                 215                 220                 225

 Val Val Met Val His Glu Pro Lys Gln Lys Val Asp Leu Thr Arg
                 230                 235                 240

 Tyr Leu Glu Asn Gln Thr Phe Arg Phe Asp Tyr Ala Phe Asp Asp
                 245                 250                 255

 Ser Ala Pro Asn Glu Met Val Tyr Arg Phe Thr Ala Lys Pro Leu
                 260                 265                 270

 Val Glu Thr Ile Phe Glu Arg Gly Met Ala Thr Cys Phe Ala Tyr
                 275                 280                 285

 Gly Gln Thr Gly Ser Gly Lys Thr His Thr Met Gly Gly Asp Phe
                 290                 295                 300

 Ser Gly Lys Asn Gln Asp Cys Ser Lys Gly Ile Tyr Ala Leu Ala
                 305                 310                 315

 Ala Arg Asp Val Phe Leu Met Leu Lys Lys Pro Asn Tyr Lys Lys
                 320                 325                 330

 Leu Glu Leu Gln Val Tyr Ala Thr Phe Phe Glu Ile Tyr Ser Gly
                 335                 340                 345

 Lys Val Phe Asp Leu Leu Asn Arg Lys Thr Lys Leu Arg Val Leu
                 350                 355                 360

 Glu Asp Gly Lys Gln Gln Val Gln Val Val Gly Leu Gln Glu Arg
                 365                 370                 375

 Glu Val Lys Cys Val Glu Asp Val Leu Lys Leu Ile Asp Ile Gly
                 380                 385                 390

 Asn Ser Cys Arg Thr Ser Gly Gln Thr Ser Ala Asn Ala His Ser
                 395                 400                 405

 Ser Arg Ser His Ala Val Phe Gln Ile Ile Leu Arg Arg Lys Gly
                 410                 415                 420

 Lys Leu His Gly Lys Phe Ser Leu Ile Asp Leu Ala Gly Asn Glu
                 425                 430                 435

 Arg Gly Ala Asp Thr Ser Ser Ala Asp Arg Gln Thr Arg Leu Glu
                 440                 445                 450

 Gly Ala Glu Ile Asn Lys Ser Leu Leu Ala Leu Lys Glu Cys Ile
                 455                 460                 465

 Arg Ala Leu Gly Arg Asn Lys Pro His Thr Pro Phe Arg Ala Ser
                 470                 475                 480

 Lys Leu Thr Gln Val Leu Arg Asp Ser Phe Ile Gly Glu Asn Ser
                 485                 490                 495

 Arg Thr Cys Met Ile Ala Thr Ile Ser Pro Gly Met Ala Ser Cys
                 500                 505                 510

 Glu Asn Thr Leu Asn Thr Leu Arg Tyr Ala Asn Arg Val Lys Glu
                 515                 520                 525

 Leu Thr Val Asp Pro Thr Ala Ala Gly Asp Val Arg Pro Ile Met
                 530                 535                 540

 His His Pro Pro Asn Gln Ile Asp Asp Leu Glu Thr Gln Trp Gly
                 545                 550                 555

 Val Gly Ser Ser Pro Gln Arg Asp Asp Leu Lys Leu Leu Cys Glu
                 560                 565                 570

 Gln Asn Glu Glu Glu Val Ser Pro Gln Leu Phe Thr Phe His Glu
                 575                 580                 585

 Ala Val Ser Gln Met Val Glu Met Glu Glu Gln Val Val Glu Asp
                 590                 595                 600

 His Arg Ala Val Phe Gln Glu Ser Ile Arg Trp Leu Glu Asp Glu
                 605                 610                 615

 Lys Ala Leu Leu Glu Met Thr Glu Glu Val Asp Tyr Asp Val Asp
                 620                 625                 630

 Ser Tyr Ala Thr Gln Leu Glu Ala Ile Leu Glu Gln Lys Ile Asp
                 635                 640                 645

 Ile Leu Thr Glu Leu Arg Asp Lys Val Lys Ser Phe Arg Ala Ala
                 650                 655                 660

 Leu Gln Glu Glu Glu Gln Ala Ser Lys Gln Ile Asn Pro Lys Arg
                 665                 670                 675

 Pro Arg Ala Leu


<210> 795
<211> 1875
<212> DNA
<213> Homo sapien

<400> 795
 ccgcccgggc aggtgctggt gccgctgtcc acggagatgc ctcggcagtg 50

 gaatccaatt tctttccagc cacaacctac cccatgggtc gacctatcag 100

 atgcgccggc cgggcggaga gctgccactg tccaaatcat attcttctgg 150

 aaacagaaaa ggctttctgt ccggcttgct agataatgtc aaacaagaat 200

 tagccaaaaa caaagaaatg aaagaaagta taaaaaaatt ccgtgacgag 250

 gccagaaggc tagaagaatc agacgtgctc caggaggcca gaaggaaata 300

 caaaaccatc gagtcagaaa ccgtgcggac aagcgaggtg ctacggaaga 350

 agcttgggga gctgacgggc accgtgaagg agagccttca cgaagtcagt 400

 aaaagtgatc tcggccggaa aatcaaggag ggcgtggagg aagcagccaa 450

 gacggccaag cagtcggccg agtcggtatc caaaggcggg gagaagctgg 500

 gcaggacagc ggccttcaga gccctctccc agggggtgga gtccgtgaag 550

 aaggaaattg acgacagcgt cctgggacag accgggccct accggaggcc 600

 ccagcgactc cggaagagaa cggagtttgc gggagataag ttcaaggagg 650

 agaaagtgtt tgagccaaac gaggaggccc tgggggtcgt gctgcacaag 700

 gactccaagt ggtaccagca gtggaaggac ttcaaggaga acaacgtggt 750

 gtttaaccgg ttcttcgaga tgaagatgaa gtatgacgaa agcgacaacg 800

 cgttcatccg ggcatcccgg gcccttacgg acaaggtcac cgacttgctg 850

 gggggcctgt tctccaagac agagatgtcg gaggtgctca cggagatcct 900

 ccgggtggac ccgccctttg acaaggaccg gtttctgaaa cagtgcgaga 950

 acgacatcat ccccaatgtc ctggaggcca tgatttctgg agagcttgac 1000

 attctcaaag actggtgcta tgaagctact tacagccagc tggcccaccc 1050

 catccagcag gccaaggcac tgggtctcca gttccattct cgcatcctag 1100

 acattgacaa cgtcgacctg gccatgggca agatgatgga gcaggggccg 1150

 gtgctgatca tcaccttcca ggcacagctg gtgatggtgg tcaggaaccc 1200

 caaaggcgag gtggtggagg gtgacccgga caaggtgctg cggatgctgt 1250

 acgtgtgggc gctctgccga gaccaggacg agctcaaccc ctacgcggcc 1300

 tggcggctcc tggacatctc ggcctccagc accgagcaga ttctctgagt 1350

 gtggtgccgg agccaggtag ccccggcctg ggtcatcagg cacagaggca 1400

 ccgcaacacc acctgcggca actccagacc tctgggaaca agactgcggg 1450

 ctctgccccc agctctgcca ggacggctgc aagaccagct ggcccgggag 1500

 gggacaacgg gctgttgcgg gtgcgcggca gctggagaca ctcccccgca 1550

 gggccaaccc ctgccctgtt gctctgccct gcaggggtcc cggcgcatgg 1600

 tcacctgggg tgcacacagg tcacacagtg ccaagaggcc ccagggccca 1650

 gggactcccc ccacagcagg gtgggacccg ggacccgcgg ctcagtggcc 1700

 cgctagccac gtcagccaag ccactttagg tccatttttt aattttaaca 1750

 gtgctcttcc atcttgtgca taagcctgag atttggaaag aataaaacac 1800

 cgaattgcag aagagcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1850

 aaaacaaaaa aaaaaaaaaa aaaaa 1875

<210> 796
<211> 415
<212> PRT
<213> Homo sapien

<400> 796
 Met Arg Arg Pro Gly Gly Glu Leu Pro Leu Ser Lys Ser Tyr Ser
   1               5                  10                  15

 Ser Gly Asn Arg Lys Gly Phe Leu Ser Gly Leu Leu Asp Asn Val
                  20                  25                  30

 Lys Gln Glu Leu Ala Lys Asn Lys Glu Met Lys Glu Ser Ile Lys
                  35                  40                  45

 Lys Phe Arg Asp Glu Ala Arg Arg Leu Glu Glu Ser Asp Val Leu
                  50                  55                  60

 Gln Glu Ala Arg Arg Lys Tyr Lys Thr Ile Glu Ser Glu Thr Val
                  65                  70                  75

 Arg Thr Ser Glu Val Leu Arg Lys Lys Leu Gly Glu Leu Thr Gly
                  80                  85                  90

 Thr Val Lys Glu Ser Leu His Glu Val Ser Lys Ser Asp Leu Gly
                  95                 100                 105

 Arg Lys Ile Lys Glu Gly Val Glu Glu Ala Ala Lys Thr Ala Lys
                 110                 115                 120

 Gln Ser Ala Glu Ser Val Ser Lys Gly Gly Glu Lys Leu Gly Arg
                 125                 130                 135

 Thr Ala Ala Phe Arg Ala Leu Ser Gln Gly Val Glu Ser Val Lys
                 140                 145                 150

 Lys Glu Ile Asp Asp Ser Val Leu Gly Gln Thr Gly Pro Tyr Arg
                 155                 160                 165

 Arg Pro Gln Arg Leu Arg Lys Arg Thr Glu Phe Ala Gly Asp Lys
                 170                 175                 180

 Phe Lys Glu Glu Lys Val Phe Glu Pro Asn Glu Glu Ala Leu Gly
                 185                 190                 195

 Val Val Leu His Lys Asp Ser Lys Trp Tyr Gln Gln Trp Lys Asp
                 200                 205                 210

 Phe Lys Glu Asn Asn Val Val Phe Asn Arg Phe Phe Glu Met Lys
                 215                 220                 225

 Met Lys Tyr Asp Glu Ser Asp Asn Ala Phe Ile Arg Ala Ser Arg
                 230                 235                 240

 Ala Leu Thr Asp Lys Val Thr Asp Leu Leu Gly Gly Leu Phe Ser
                 245                 250                 255

 Lys Thr Glu Met Ser Glu Val Leu Thr Glu Ile Leu Arg Val Asp
                 260                 265                 270

 Pro Pro Phe Asp Lys Asp Arg Phe Leu Lys Gln Cys Glu Asn Asp
                 275                 280                 285

 Ile Ile Pro Asn Val Leu Glu Ala Met Ile Ser Gly Glu Leu Asp
                 290                 295                 300

 Ile Leu Lys Asp Trp Cys Tyr Glu Ala Thr Tyr Ser Gln Leu Ala
                 305                 310                 315

 His Pro Ile Gln Gln Ala Lys Ala Leu Gly Leu Gln Phe His Ser
                 320                 325                 330

 Arg Ile Leu Asp Ile Asp Asn Val Asp Leu Ala Met Gly Lys Met
                 335                 340                 345

 Met Glu Gln Gly Pro Val Leu Ile Ile Thr Phe Gln Ala Gln Leu
                 350                 355                 360

 Val Met Val Val Arg Asn Pro Lys Gly Glu Val Val Glu Gly Asp
                 365                 370                 375

 Pro Asp Lys Val Leu Arg Met Leu Tyr Val Trp Ala Leu Cys Arg
                 380                 385                 390

 Asp Gln Asp Glu Leu Asn Pro Tyr Ala Ala Trp Arg Leu Leu Asp
                 395                 400                 405

 Ile Ser Ala Ser Ser Thr Glu Gln Ile Leu
                 410                 415

<210> 797
<211> 6568
<212> DNA
<213> Homo sapien

<400> 797
 cttgccatcg tgagagattg gtacatgatg tgtaaattca gttcagcata 50

 tgtttcttca ttatgaaacc actagcaatc ccagctaacc atggagttat 100

 gggccagcag gagaaacact cacttcctgc agatttcaca aaactgcatc 150

 ttactgacag tctccaccca caggtgaccc acgtttcttc tagccattca 200

 ggatgtagta tcactagtga ttctgggagc agcagtcttt ctgatatcta 250

 ccaggccaca gaaagcgagg ctggtgatat ggacctgagt gggttgccag 300

 aaacagcagt ggattccgaa gacgacgacg atgaagaaga cattgagaga 350

 gcatcagatc ctctgatgag cagggacatt gtgagagact gcctagagaa 400

 ggacccaatt gaccggacag atgatgacat tgaacaactc ttggaattta 450

 tgcaccagtt gcctgctttt gccaatatga caatgtcagt gaggcgagaa 500

 ctctgtgctg tgatggtgtt cgcagtggtg gaaagagcag ggaccatagt 550

 gttaaatgat ggtgaagagc tggactcctg gtcagtgatt ctcaatggat 600

 ctgtggaagt gacttatcca gatggaaaag cagaaatact gtgcatggga 650

 aatagttttg gtgtctctcc taccatggac aaagaataca tgaaaggagt 700

 gatgagaaca aaggtggatg actgccagtt tgtctgcata gcccagcaag 750

 attactgccg tattctcaat caagtagaaa agaacatgca aaaagttgaa 800

 gaggaaggag agattgttat ggtgaaagaa caccgagaac ttgatcgaac 850

 tggaacaaga aagggacaca ttgtcatcaa gggtacctca gaaaggttaa 900

 caatgcattt ggtggaagag cattcagtag tagatccaac attcatagaa 950

 gactttctgt tgacctatag gacttttctt tctagcccaa tggaagtggg 1000

 caaaaagtta ttggagtggt ttaatgaccc gagcctcagg gataaggtta 1050

 cacgggtagt attattgtgg gtaaataatc acttcaatga ctttgaagga 1100

 gatcctgcaa tgactcgatt tttagaagaa tttgaaaaca atctggaaag 1150

 agagaaaatg ggtggacacc taaggctgtt gaatatcgcg tgtgctgcta 1200

 aagcaaaaag aagattgatg acgttaacaa aaccatcccg agaagctcct 1250

 ttgcctttta tcttacttgg aggctctgag aagggatttg gaatctttgt 1300

 tgacagtgta gattcaggta gcaaagcaac tgaagcaggc ttgaaacggg 1350

 gggatcagat attagaagta aatggccaaa actttgaaaa cattcagctg 1400

 tcaaaagcta tggaaattct tagaaataac acacatttat ctatcactgt 1450

 gaaaaccaat ttatttgtat ttaaagaact tctaacaaga ttgtcagaag 1500

 agaaaagaaa tggtgccccc caccttccta aaattggtga cattaaaaag 1550

 gccagtcgct actccattcc agatcttgct gtagatgtag aacaggtgat 1600

 aggacttgaa aaagtgaaca aaaaaagtaa agccaacact gtgggaggaa 1650

 ggaacaagct gaaaaagata ctcgacaaga ctcggatcag tatcttgcca 1700

 cagaaaccat acaatgatat tgggattggt cagtctcaag atgacagcat 1750

 agtaggatta aggcagacaa agcacatccc aactgcattg cctgtcagtg 1800

 gaaccttatc atccagtaat cctgatttat tgcagtcaca tcatcgcatt 1850

 ttagacttca gtgctactcc tgacttgcca gatcaagtgc taagggtttt 1900

 taaggctgat cagcaaagcc gctacatcat gatcagtaag gacactacag 1950

 caaaggaagt ggtcattcag gctatcaggg agtttgctgt tactgccacc 2000

 ccggatcaat attcactatg tgaggtctct gtcacacctg agggagtaat 2050

 caaacaaaga agacttccag atcagctttc caaacttgca gacagaatac 2100

 aactgagtgg aaggtattat ctgaaaaaca acatggaaac agaaactctt 2150

 tgttcagatg aagatgctca ggagttgttg agagagagtc aaatttccct 2200

 ccttcagctc agcactgtgg aagttgcaac acagctctct atgcgaaatt 2250

 ttgaactctt tcgcaacatt gaacctactg aatatataga tgatttattt 2300

 aaactcagat caaaaaccag ctgtgccaac ctgaagagat ttgaagaagt 2350

 cattaaccag gaaacatttt gggtagcatc tgaaattctc agagaaacaa 2400

 accagctgaa gaggatgaag atcattaagc atttcatcaa gatagcactg 2450

 cactgtaggg aatgcaagaa ttttaactca atgtttgcaa tcatcagtgg 2500

 cctaaacctg gcaccagtgg caagactgcg aacgacctgg gagaaacttc 2550

 ccaataaata cgaaaaacta tttcaagatc tccaagacct gtttgatcct 2600

 tccagaaaca tggcaaaata tcgtaatgtt ctcaatagtc aaaatctaca 2650

 acctcccata atccctctat tcccagttat caaaaaggat ctcaccttcc 2700

 ttcacgaagg aaatgactca aaagtagacg ggctggtcaa ttttgagaag 2750

 ctaaggatga ttgcaaaaga aattcgtcac gttggccgaa tggcttcagt 2800

 gaacatggac cctgccctca tgttcaggac tcggaagaag aaatggcgga 2850

 gtttggggtc tctcagccag ggtagtacaa atgcaacagt gctagatgtt 2900

 gctcagacag gtggtcataa aaagcgggta cgtcgtagtt cctttctcaa 2950

 tgccaaaaag ctttatgaag atgcccaaat ggctcgaaaa gtgaagcagt 3000

 acctttccaa tttggagcta gaaatggacg aggagagtct tcagacatta 3050

 tctctgcagt gtgagccagc aaccaacaca ttgcctaaga atcctggtga 3100

 caaaaagcct gtcaaatccg agacctctcc agtagctcca agggcagggt 3150

 cacaacagaa agctcagtcc ctgccacagc cccagcagca gccaccacca 3200

 gcacataaaa tcaaccaggg actacaggtt cccgccgtgt ccctttatcc 3250

 ttcacggaag aaagtgcccg taaaggatct cccacctttt ggcataaact 3300

 ctccacaagc tttaaaaaaa attctttctt tgtctgaaga aggaagtttg 3350

 gaacgtcaca agaaacaggc tgaagataca atatcaaatg catcttcgca 3400

 gctttcttct cctcctactt ctccacagag ttctccaagg aaaggctata 3450

 ctttggctcc cagtggtact gtggataatt tttcagattc tggtcacagt 3500

 gaaatttctt cacgatccag tattgttagc aattcgtctt ttgactcagt 3550

 gccagtctca ctgcacgatg agaggcgcca gaggcattct gtcagcatcg 3600

 tggaaacaaa cctagggatg ggcaggatgg agaggcggac catgattgaa 3650

 cctgatcagt atagcttggg gtcctatgca ccaatgtccg agggccgagg 3700

 cttatatgct acagctacag taatttcttc tccaagcaca gaggaacttt 3750

 cccaggatca gggggatcgc gcgtcacttg atgctgctga cagtggccgt 3800

 gggagctgga cgtcatgctc aagtggctcc catgataata tacagacgat 3850

 ccagcaccag agaagctggg agactcttcc attcgggcat actcactttg 3900

 attattcagg ggatcctgca ggtttatggg catcaagcag ccatatggac 3950

 caaattatgt tttctgatca tagcacaaag tataacaggc aaaatcaaag 4000

 tagagagagc cttgaacaag cccagtcccg agcaagctgg gcgtcttcca 4050

 caggttactg gggagaagac tcagaaggtg acacaggcac aataaagcgg 4100

 aggggtggaa aggatgtttc cattgaagcc gaaagcagta gcctaacgtc 4150

 tgtgactacg gaagaaacca agcctgtccc catgcctgcc cacatagctg 4200

 tggcatcaag tactacaaag gggctcattg cacgaaagga gggcaggtat 4250

 cgagagcccc cgcccacccc tcccggctac attggaattc ccattactga 4300

 ctttccagaa gggcactccc atccagccag gaaaccgccg gactacaacg 4350

 tggcccttca gagatcgcgg atggtcgcac gatcctccga cacagctggg 4400

 ccttcatccg tacagcagcc acatgggcat cccaccagca gcaggcctgt 4450

 gaacaaacct cagtggcata aaccgaacga gtctgacccg cgcctcgccc 4500

 cttatcagtc ccaagggttt tccaccgagg aggatgaaga tgaacaagtt 4550

 tctgctgttt gaggcacaga cttttctgga agcagagcga gccacctgaa 4600

 aggagagcac aagaagacgt cctgagcatt ggagccttgg aactcacatt 4650

 ctgaggacgg tggaccagtt tgcctccttc cctgccttaa aagcagcatg 4700

 gggcttcttc tccccttctt cctttcccct ttgcatgtga aatactgtga 4750

 agaaattgcc ctggcacttt tcagactttg ttgcttgaaa tgcacagtgc 4800

 agcaatcttc gagctcccac tgttgctgcc tgccacatca cacagtatca 4850

 ttccaaattc caagatcatc acaacaagat gattcactct ggctgcactt 4900

 ctcaatgcct ggaaggattt tttttaatct tccttttaga tttcaatcca 4950

 gtcctagcac ttgatctcat tgggataatg agaaaagcta gccattgaac 5000

 tacttggggc ctttaaccca ccaaggaaga caaagaaaaa caatgaaatc 5050

 ctttgagtac agtgcttgtc cacttgttta caatgtcctc cttttaaaaa 5100

 aaaaaatgag tttaaagatt ttgttcagag agtaaatata tatccattta 5150

 atgattacag tattatttta aaccttaagt agggttgcca gcctggtttc 5200

 tgaaaaacca aatatgccgg acagggtgtg gccacaccaa gaagacggga 5250

 agacctggct tgtgaccctg gcttcccatg tccttctggt ctcacccgcg 5300

 aagtgcccta tcctggaagt atgaaatgtt agccaattaa taccaagaca 5350

 cctcatctgc tccttcccca gtggatgggg ttcttctgta aaactgtttg 5400

 cacatggcca ggggagggaa ctaggaccct tgtgtcctgt ctgagcctta 5450

 tggaggcagg acggtgtcat tggcggatgt gtcctgctcc attgagatgg 5500

 atggcaaacc ccatttttaa gttatatttc tttgattttt gttaatttag 5550

 aggtgtaggt tttgtttttt gttttttgtt tttttttaag agaaacattt 5600

 ataactggat agcattgcag tgaaagcagc ttgggatgtt ggagctaatg 5650

 ccagctgttt atactgctct ttcaagacag cctcccttta ttgaattggc 5700

 attagggaat aaacaagcct ttaaacgtga taaaagatca aaaacctggt 5750

 tagacatgcc agcctttgca aggcaggtta gtcaccaaag actaacctcc 5800

 aagtggcttt atggacgctg catatagaga aggcctaagt gtagcaacca 5850

 tctgctcaca gctgctatta accctataat gactgaaatg acccctccac 5900

 tctatttttg tgttgttttg cacagactcc ggaaaagtga aggctgccaa 5950

 tctgagtagt actcaaatgt gaggaactgc tggtcttgga ttttttttcc 6000

 attaaattca gctgatcata ttgatcagta gataaacgta aatagcttca 6050

 aattttaaaa gtggaattgc agtgtttttt cactgtatca aacaatgtca 6100

 gtgctttatt taataattct cttctgtatc atggcatttg tctacttgct 6150

 tattacattg tcaattatgc atttgtaatt ttacatgtaa tatgcattat 6200

 ttgccagttt tattatatag gctatggacc tcatgtgcat atagaaagac 6250

 agaaatctag ctctaccaca agttgcacaa atgttatcta agcattaagt 6300

 aattgtagaa cataggactg ctaatctcag ttcgctctgt gatgtcaagt 6350

 gcagaatgta caattaactg gtgatttcct catacttttg atactacttg 6400

 tacctgtatg tcttttagaa agacattggt ggagtctgta tcccttttgt 6450

 atttttaata caataattgt acatattggt tatatttttg ttgaagatgg 6500

 tagaaatgta ctatgtttat gcttctacat ccagtttgta caagctggaa 6550

 aataaataaa tataacat 6568

<210> 798
<211> 1499
<212> PRT
<213> Homo sapien

<400> 798
 Met Lys Pro Leu Ala Ile Pro Ala Asn His Gly Val Met Gly Gln
   1               5                  10                  15

 Gln Glu Lys His Ser Leu Pro Ala Asp Phe Thr Lys Leu His Leu
                  20                  25                  30

 Thr Asp Ser Leu His Pro Gln Val Thr His Val Ser Ser Ser His
                  35                  40                  45

 Ser Gly Cys Ser Ile Thr Ser Asp Ser Gly Ser Ser Ser Leu Ser
                  50                  55                  60

 Asp Ile Tyr Gln Ala Thr Glu Ser Glu Ala Gly Asp Met Asp Leu
                  65                  70                  75

 Ser Gly Leu Pro Glu Thr Ala Val Asp Ser Glu Asp Asp Asp Asp
                  80                  85                  90

 Glu Glu Asp Ile Glu Arg Ala Ser Asp Pro Leu Met Ser Arg Asp
                  95                 100                 105

 Ile Val Arg Asp Cys Leu Glu Lys Asp Pro Ile Asp Arg Thr Asp
                 110                 115                 120

 Asp Asp Ile Glu Gln Leu Leu Glu Phe Met His Gln Leu Pro Ala
                 125                 130                 135

 Phe Ala Asn Met Thr Met Ser Val Arg Arg Glu Leu Cys Ala Val
                 140                 145                 150

 Met Val Phe Ala Val Val Glu Arg Ala Gly Thr Ile Val Leu Asn
                 155                 160                 165

 Asp Gly Glu Glu Leu Asp Ser Trp Ser Val Ile Leu Asn Gly Ser
                 170                 175                 180

 Val Glu Val Thr Tyr Pro Asp Gly Lys Ala Glu Ile Leu Cys Met
                 185                 190                 195

 Gly Asn Ser Phe Gly Val Ser Pro Thr Met Asp Lys Glu Tyr Met
                 200                 205                 210

 Lys Gly Val Met Arg Thr Lys Val Asp Asp Cys Gln Phe Val Cys
                 215                 220                 225

 Ile Ala Gln Gln Asp Tyr Cys Arg Ile Leu Asn Gln Val Glu Lys
                 230                 235                 240

 Asn Met Gln Lys Val Glu Glu Glu Gly Glu Ile Val Met Val Lys
                 245                 250                 255

 Glu His Arg Glu Leu Asp Arg Thr Gly Thr Arg Lys Gly His Ile
                 260                 265                 270

 Val Ile Lys Gly Thr Ser Glu Arg Leu Thr Met His Leu Val Glu
                 275                 280                 285

 Glu His Ser Val Val Asp Pro Thr Phe Ile Glu Asp Phe Leu Leu
                 290                 295                 300

 Thr Tyr Arg Thr Phe Leu Ser Ser Pro Met Glu Val Gly Lys Lys
                 305                 310                 315

 Leu Leu Glu Trp Phe Asn Asp Pro Ser Leu Arg Asp Lys Val Thr
                 320                 325                 330

 Arg Val Val Leu Leu Trp Val Asn Asn His Phe Asn Asp Phe Glu
                 335                 340                 345

 Gly Asp Pro Ala Met Thr Arg Phe Leu Glu Glu Phe Glu Asn Asn
                 350                 355                 360

 Leu Glu Arg Glu Lys Met Gly Gly His Leu Arg Leu Leu Asn Ile
                 365                 370                 375

 Ala Cys Ala Ala Lys Ala Lys Arg Arg Leu Met Thr Leu Thr Lys
                 380                 385                 390

 Pro Ser Arg Glu Ala Pro Leu Pro Phe Ile Leu Leu Gly Gly Ser
                 395                 400                 405

 Glu Lys Gly Phe Gly Ile Phe Val Asp Ser Val Asp Ser Gly Ser
                 410                 415                 420

 Lys Ala Thr Glu Ala Gly Leu Lys Arg Gly Asp Gln Ile Leu Glu
                 425                 430                 435

 Val Asn Gly Gln Asn Phe Glu Asn Ile Gln Leu Ser Lys Ala Met
                 440                 445                 450

 Glu Ile Leu Arg Asn Asn Thr His Leu Ser Ile Thr Val Lys Thr
                 455                 460                 465

 Asn Leu Phe Val Phe Lys Glu Leu Leu Thr Arg Leu Ser Glu Glu
                 470                 475                 480

 Lys Arg Asn Gly Ala Pro His Leu Pro Lys Ile Gly Asp Ile Lys
                 485                 490                 495

 Lys Ala Ser Arg Tyr Ser Ile Pro Asp Leu Ala Val Asp Val Glu
                 500                 505                 510

 Gln Val Ile Gly Leu Glu Lys Val Asn Lys Lys Ser Lys Ala Asn
                 515                 520                 525

 Thr Val Gly Gly Arg Asn Lys Leu Lys Lys Ile Leu Asp Lys Thr
                 530                 535                 540

 Arg Ile Ser Ile Leu Pro Gln Lys Pro Tyr Asn Asp Ile Gly Ile
                 545                 550                 555

 Gly Gln Ser Gln Asp Asp Ser Ile Val Gly Leu Arg Gln Thr Lys
                 560                 565                 570

 His Ile Pro Thr Ala Leu Pro Val Ser Gly Thr Leu Ser Ser Ser
                 575                 580                 585

 Asn Pro Asp Leu Leu Gln Ser His His Arg Ile Leu Asp Phe Ser
                 590                 595                 600

 Ala Thr Pro Asp Leu Pro Asp Gln Val Leu Arg Val Phe Lys Ala
                 605                 610                 615

 Asp Gln Gln Ser Arg Tyr Ile Met Ile Ser Lys Asp Thr Thr Ala
                 620                 625                 630

 Lys Glu Val Val Ile Gln Ala Ile Arg Glu Phe Ala Val Thr Ala
                 635                 640                 645

 Thr Pro Asp Gln Tyr Ser Leu Cys Glu Val Ser Val Thr Pro Glu
                 650                 655                 660

 Gly Val Ile Lys Gln Arg Arg Leu Pro Asp Gln Leu Ser Lys Leu
                 665                 670                 675

 Ala Asp Arg Ile Gln Leu Ser Gly Arg Tyr Tyr Leu Lys Asn Asn
                 680                 685                 690

 Met Glu Thr Glu Thr Leu Cys Ser Asp Glu Asp Ala Gln Glu Leu
                 695                 700                 705

 Leu Arg Glu Ser Gln Ile Ser Leu Leu Gln Leu Ser Thr Val Glu
                 710                 715                 720

 Val Ala Thr Gln Leu Ser Met Arg Asn Phe Glu Leu Phe Arg Asn
                 725                 730                 735

 Ile Glu Pro Thr Glu Tyr Ile Asp Asp Leu Phe Lys Leu Arg Ser
                 740                 745                 750

 Lys Thr Ser Cys Ala Asn Leu Lys Arg Phe Glu Glu Val Ile Asn
                 755                 760                 765

 Gln Glu Thr Phe Trp Val Ala Ser Glu Ile Leu Arg Glu Thr Asn
                 770                 775                 780

 Gln Leu Lys Arg Met Lys Ile Ile Lys His Phe Ile Lys Ile Ala
                 785                 790                 795

 Leu His Cys Arg Glu Cys Lys Asn Phe Asn Ser Met Phe Ala Ile
                 800                 805                 810

 Ile Ser Gly Leu Asn Leu Ala Pro Val Ala Arg Leu Arg Thr Thr
                 815                 820                 825

 Trp Glu Lys Leu Pro Asn Lys Tyr Glu Lys Leu Phe Gln Asp Leu
                 830                 835                 840

 Gln Asp Leu Phe Asp Pro Ser Arg Asn Met Ala Lys Tyr Arg Asn
                 845                 850                 855

 Val Leu Asn Ser Gln Asn Leu Gln Pro Pro Ile Ile Pro Leu Phe
                 860                 865                 870

 Pro Val Ile Lys Lys Asp Leu Thr Phe Leu His Glu Gly Asn Asp
                 875                 880                 885

 Ser Lys Val Asp Gly Leu Val Asn Phe Glu Lys Leu Arg Met Ile
                 890                 895                 900

 Ala Lys Glu Ile Arg His Val Gly Arg Met Ala Ser Val Asn Met
                 905                 910                 915

 Asp Pro Ala Leu Met Phe Arg Thr Arg Lys Lys Lys Trp Arg Ser
                 920                 925                 930

 Leu Gly Ser Leu Ser Gln Gly Ser Thr Asn Ala Thr Val Leu Asp
                 935                 940                 945

 Val Ala Gln Thr Gly Gly His Lys Lys Arg Val Arg Arg Ser Ser
                 950                 955                 960

 Phe Leu Asn Ala Lys Lys Leu Tyr Glu Asp Ala Gln Met Ala Arg
                 965                 970                 975

 Lys Val Lys Gln Tyr Leu Ser Asn Leu Glu Leu Glu Met Asp Glu
                 980                 985                 990

 Glu Ser Leu Gln Thr Leu Ser Leu Gln Cys Glu Pro Ala Thr Asn
                 995                1000                1005

 Thr Leu Pro Lys Asn Pro Gly Asp Lys Lys Pro Val Lys Ser Glu
                1010                1015                1020

 Thr Ser Pro Val Ala Pro Arg Ala Gly Ser Gln Gln Lys Ala Gln
                1025                1030                1035

 Ser Leu Pro Gln Pro Gln Gln Gln Pro Pro Pro Ala His Lys Ile
                1040                1045                1050

 Asn Gln Gly Leu Gln Val Pro Ala Val Ser Leu Tyr Pro Ser Arg
                1055                1060                1065

 Lys Lys Val Pro Val Lys Asp Leu Pro Pro Phe Gly Ile Asn Ser
                1070                1075                1080

 Pro Gln Ala Leu Lys Lys Ile Leu Ser Leu Ser Glu Glu Gly Ser
                1085                1090                1095

 Leu Glu Arg His Lys Lys Gln Ala Glu Asp Thr Ile Ser Asn Ala
                1100                1105                1110

 Ser Ser Gln Leu Ser Ser Pro Pro Thr Ser Pro Gln Ser Ser Pro
                1115                1120                1125

 Arg Lys Gly Tyr Thr Leu Ala Pro Ser Gly Thr Val Asp Asn Phe
                1130                1135                1140

 Ser Asp Ser Gly His Ser Glu Ile Ser Ser Arg Ser Ser Ile Val
                1145                1150                1155

 Ser Asn Ser Ser Phe Asp Ser Val Pro Val Ser Leu His Asp Glu
                1160                1165                1170

 Arg Arg Gln Arg His Ser Val Ser Ile Val Glu Thr Asn Leu Gly
                1175                1180                1185

 Met Gly Arg Met Glu Arg Arg Thr Met Ile Glu Pro Asp Gln Tyr
                1190                1195                1200

 Ser Leu Gly Ser Tyr Ala Pro Met Ser Glu Gly Arg Gly Leu Tyr
                1205                1210                1215

 Ala Thr Ala Thr Val Ile Ser Ser Pro Ser Thr Glu Glu Leu Ser
                1220                1225                1230

 Gln Asp Gln Gly Asp Arg Ala Ser Leu Asp Ala Ala Asp Ser Gly
                1235                1240                1245

 Arg Gly Ser Trp Thr Ser Cys Ser Ser Gly Ser His Asp Asn Ile
                1250                1255                1260

 Gln Thr Ile Gln His Gln Arg Ser Trp Glu Thr Leu Pro Phe Gly
                1265                1270                1275

 His Thr His Phe Asp Tyr Ser Gly Asp Pro Ala Gly Leu Trp Ala
                1280                1285                1290

 Ser Ser Ser His Met Asp Gln Ile Met Phe Ser Asp His Ser Thr
                1295                1300                1305

 Lys Tyr Asn Arg Gln Asn Gln Ser Arg Glu Ser Leu Glu Gln Ala
                1310                1315                1320

 Gln Ser Arg Ala Ser Trp Ala Ser Ser Thr Gly Tyr Trp Gly Glu
                1325                1330                1335

 Asp Ser Glu Gly Asp Thr Gly Thr Ile Lys Arg Arg Gly Gly Lys
                1340                1345                1350

 Asp Val Ser Ile Glu Ala Glu Ser Ser Ser Leu Thr Ser Val Thr
                1355                1360                1365

 Thr Glu Glu Thr Lys Pro Val Pro Met Pro Ala His Ile Ala Val
                1370                1375                1380

 Ala Ser Ser Thr Thr Lys Gly Leu Ile Ala Arg Lys Glu Gly Arg
                1385                1390                1395

 Tyr Arg Glu Pro Pro Pro Thr Pro Pro Gly Tyr Ile Gly Ile Pro
                1400                1405                1410

 Ile Thr Asp Phe Pro Glu Gly His Ser His Pro Ala Arg Lys Pro
                1415                1420                1425

 Pro Asp Tyr Asn Val Ala Leu Gln Arg Ser Arg Met Val Ala Arg
                1430                1435                1440

 Ser Ser Asp Thr Ala Gly Pro Ser Ser Val Gln Gln Pro His Gly
                1445                1450                1455

 His Pro Thr Ser Ser Arg Pro Val Asn Lys Pro Gln Trp His Lys
                1460                1465                1470

 Pro Asn Glu Ser Asp Pro Arg Leu Ala Pro Tyr Gln Ser Gln Gly
                1475                1480                1485

 Phe Ser Thr Glu Glu Asp Glu Asp Glu Gln Val Ser Ala Val
                1490                1495

<210> 799
<211> 2677
<212> DNA
<213> Homo sapien

<400> 799
 gggcgcggtg tgccgcgggg cagttgcggg ttgtcataac ggtccccgcc 50

 ggagtgaggc gaggccgcgt cgctcagttc tggccgtcta gggcccctgt 100

 aaggatgaga gcgcagagga cgcagggccg ctggaggcgc aggtaacgaa 150

 gctagggtgc ggttgggacc gcggctgagc tttttccggg acccgtggtg 200

 ctgaatggag aggacggaga cgaagccgag ccgcggctcc tagcggcggc 250

 gccgatgctc gagctgtagc tgccaggcga ggatgtgtgg agcgcaggcg 300

 gcgcggggta aatgagaggt ctcgggcccc aggacccccg gggcccggga 350

 tgagttagcg agggcagccg cgggggccag ttccgaccgt gacaggccaa 400

 ggcgacggcc gccgcccgcc cgccccttcc gtgcagaagc agctgctcct 450

 ttccgcgccc gcccgcctgc gctcccggcc ctggagacca tgaggttccg 500

 catctacaaa cggaaggtgc taatcctgac gctcgtggtg gccgcctgcg 550

 gcttcgtcct ctggagcagc aatgggcgac aaaggaagaa cgaggccctc 600

 gccccaccgt tgctggacgc cgaacccgcg cggggtgccg gcggccgcgg 650

 tggggaccac ccctctgtgg ctgtgggcat ccgcagggtc tccaacgtgt 700

 cggcggcttc cctggtcccg gcggtccccc agcccgaggc ggacaacctg 750

 acgctgcggt accggtccct ggtgtaccag ctgaactttg atcagaccct 800

 gaggaatgta gataaggctg gcacctgggc cccccgggag ctggtgctgg 850

 tggtccaggt gcataaccgg cccgaatacc tcagactgct gctggactca 900

 cttcgaaaag cccagggaat tgacaacgtc ctcgtcatct ttagccatga 950

 cttctggtcg accgagatca atcagctgat cgccggggtg aatttctgtc 1000

 cggttctgca ggtgttcttt cctttcagca ttcagttgta ccctaacgag 1050

 tttccaggta gtgaccctag agattgtccc agagacctgc cgaagaatgc 1100

 cgctttgaaa ttggggtgca tcaatgctga gtatcccgac tccttcggcc 1150

 attatagaga ggccaaattc tcccagacca aacatcactg gtggtggaag 1200

 ctgcattttg tgtgggaaag agtgaaaatt cttcgagatt atgctggcct 1250

 tatacttttc ctagaagagg atcactactt agccccagac ttttaccatg 1300

 tcttcaaaaa gatgtggaaa ctgaagcagc aagagtgccc tgaatgtgat 1350

 gttctctccc tggggaccta tagtgccagt cgcagtttct atggcatggc 1400

 tgacaaggta gatgtgaaaa cttggaaatc cacagagcac aatatgggtc 1450

 tagccttgac ccggaatgcc tatcagaagc tgatcgagtg cacagacact 1500

 ttctgtactt atgatgatta taactgggac tggactcttc aatacttgac 1550

 tgtatcttgt cttccaaaat tctggaaagt gctggttcct caaattccta 1600

 ggatctttca tgctggagac tgtggtatgc atcacaagaa aacctgtaga 1650

 ccatccactc agagtgccca aattgagtca ctcttaaata ataacaaaca 1700

 atacatgttt ccagaaactc taactatcag tgaaaagttt actgtggtag 1750

 ccatttcccc acctagaaaa aatggagggt ggggagatat tagggaccat 1800

 gaactctgta aaagttatag aagactgcag tgaaaatcac agttacaaaa 1850

 gcgacagtct tctatttttg atatttgtcc aaacaggaca tacaattgaa 1900

 taaaagagtt taggaactgg tttctgcttt aatacaaaaa caaaatcttg 1950

 taaaaggtgt ccaaatacat agtaatcttt tccagttatg tctgattaag 2000

 atttaaaact gaaggtttca ttttgggagt agggttttaa agctcaatct 2050

 gttatctgct aaaattgatt attgttgata tgagagaaga ggggaaattt 2100

 tatttaaatt gcatttatta atctttttat ctgaaacttt gtacactttt 2150

 ccactttcaa aacctatttt aagtacagca aaatttattt aaaactgtga 2200

 tagcagtaaa aagtattacg atgaaattgt tagggtatta atggaacaaa 2250

 cccagtttca ctctcttgac acacttatta ggaagggatt gcttcactgg 2300

 tttaataatt taaaagttat gtttgttaaa caccctgtca gaacagtcat 2350

 tttcagtatt agattcctgt actattgtgt tttgagtgtg ttttggaacc 2400

 ttcatagaac acactttctt ttggaatgta tttgattgat aagaaagttt 2450

 aaacattgtt ttcacctcaa tgtagaaata cagtggtttt gttttttttt 2500

 ttcttttagt gctgacaaaa taaaatactc atttttgcat aaaaaggttc 2550

 ctaatccttt tgcagaataa gttttgttta ctctttatac caaaattcag 2600

 tgaaggcatt ctacaagttt tgagttagca ttacatttta atatttacta 2650

 ttgctacatt gtataattga gtttgaa 2677

<210> 800
<211> 447
<212> PRT
<213> Homo sapien

<400> 800
 Met Arg Phe Arg Ile Tyr Lys Arg Lys Val Leu Ile Leu Thr Leu
   1               5                  10                  15

 Val Val Ala Ala Cys Gly Phe Val Leu Trp Ser Ser Asn Gly Arg
                  20                  25                  30

 Gln Arg Lys Asn Glu Ala Leu Ala Pro Pro Leu Leu Asp Ala Glu
                  35                  40                  45

 Pro Ala Arg Gly Ala Gly Gly Arg Gly Gly Asp His Pro Ser Val
                  50                  55                  60

 Ala Val Gly Ile Arg Arg Val Ser Asn Val Ser Ala Ala Ser Leu
                  65                  70                  75

 Val Pro Ala Val Pro Gln Pro Glu Ala Asp Asn Leu Thr Leu Arg
                  80                  85                  90

 Tyr Arg Ser Leu Val Tyr Gln Leu Asn Phe Asp Gln Thr Leu Arg
                  95                 100                 105

 Asn Val Asp Lys Ala Gly Thr Trp Ala Pro Arg Glu Leu Val Leu
                 110                 115                 120

 Val Val Gln Val His Asn Arg Pro Glu Tyr Leu Arg Leu Leu Leu
                 125                 130                 135

 Asp Ser Leu Arg Lys Ala Gln Gly Ile Asp Asn Val Leu Val Ile
                 140                 145                 150

 Phe Ser His Asp Phe Trp Ser Thr Glu Ile Asn Gln Leu Ile Ala
                 155                 160                 165

 Gly Val Asn Phe Cys Pro Val Leu Gln Val Phe Phe Pro Phe Ser
                 170                 175                 180

 Ile Gln Leu Tyr Pro Asn Glu Phe Pro Gly Ser Asp Pro Arg Asp
                 185                 190                 195

 Cys Pro Arg Asp Leu Pro Lys Asn Ala Ala Leu Lys Leu Gly Cys
                 200                 205                 210

 Ile Asn Ala Glu Tyr Pro Asp Ser Phe Gly His Tyr Arg Glu Ala
                 215                 220                 225

 Lys Phe Ser Gln Thr Lys His His Trp Trp Trp Lys Leu His Phe
                 230                 235                 240

 Val Trp Glu Arg Val Lys Ile Leu Arg Asp Tyr Ala Gly Leu Ile
                 245                 250                 255

 Leu Phe Leu Glu Glu Asp His Tyr Leu Ala Pro Asp Phe Tyr His
                 260                 265                 270

 Val Phe Lys Lys Met Trp Lys Leu Lys Gln Gln Glu Cys Pro Glu
                 275                 280                 285

 Cys Asp Val Leu Ser Leu Gly Thr Tyr Ser Ala Ser Arg Ser Phe
                 290                 295                 300

 Tyr Gly Met Ala Asp Lys Val Asp Val Lys Thr Trp Lys Ser Thr
                 305                 310                 315

 Glu His Asn Met Gly Leu Ala Leu Thr Arg Asn Ala Tyr Gln Lys
                 320                 325                 330

 Leu Ile Glu Cys Thr Asp Thr Phe Cys Thr Tyr Asp Asp Tyr Asn
                 335                 340                 345

 Trp Asp Trp Thr Leu Gln Tyr Leu Thr Val Ser Cys Leu Pro Lys
                 350                 355                 360

 Phe Trp Lys Val Leu Val Pro Gln Ile Pro Arg Ile Phe His Ala
                 365                 370                 375

 Gly Asp Cys Gly Met His His Lys Lys Thr Cys Arg Pro Ser Thr
                 380                 385                 390

 Gln Ser Ala Gln Ile Glu Ser Leu Leu Asn Asn Asn Lys Gln Tyr
                 395                 400                 405

 Met Phe Pro Glu Thr Leu Thr Ile Ser Glu Lys Phe Thr Val Val
                 410                 415                 420

 Ala Ile Ser Pro Pro Arg Lys Asn Gly Gly Trp Gly Asp Ile Arg
                 425                 430                 435

 Asp His Glu Leu Cys Lys Ser Tyr Arg Arg Leu Gln
                 440                 445

<210> 801
<211> 751
<212> DNA
<213> Homo sapien

<400> 801
 aggatgatca agctgttctc gctgaagcag cagaagaagg aggaggagtc 50

 ggcgggcggc accaagggca gcagcaagaa ggcgtcggcg gcgcagctgc 100

 ggatccagaa ggacataaac gagctgaacc tgcccaagac gtgtgatatc 150

 agcttctcag atccagacga cctcctcaac ttcaagctgg tcatctgtcc 200

 tgatgagggc ttctacaaga gtgggaagtt tgtgttcagt tttaaggtgg 250

 gccagggtta cccgcatgat ccccccaagg tgaagtgtga gacaatggtc 300

 tatcacccca acattgacct cgagggcaac gtctgcctca acatcctcag 350

 agaggactgg aagccagtcc ttacgataaa ctccataatt tatggcctgc 400

 agtatctctt cttggagccc aaccccgagg acccactgaa caaggaggcc 450

 gcagaggtcc tgcagaacaa ccggcggctg tttgagcaga acgtgcagcg 500

 ctccatgcgg ggtggctaca tcggctccac ctactttgag cgctgcctga 550

 aatagggttg gcgcataccc acccgccgcc acggccacaa gccctggcat 600

 cccctgcaaa tatttattgg gggccatggg taggggtttg gggggcggcc 650

 ggtgggggaa tcccctgcct tggccttgcc tccccttcct gccacgtgcc 700

 cctagttatt ttttttttaa caccaggcta actaaagggg aatgttactg 750

 c 751

<210> 802
<211> 183
<212> PRT
<213> Homo sapien

<400> 802
 Met Ile Lys Leu Phe Ser Leu Lys Gln Gln Lys Lys Glu Glu Glu
   1               5                  10                  15

 Ser Ala Gly Gly Thr Lys Gly Ser Ser Lys Lys Ala Ser Ala Ala
                  20                  25                  30

 Gln Leu Arg Ile Gln Lys Asp Ile Asn Glu Leu Asn Leu Pro Lys
                  35                  40                  45

 Thr Cys Asp Ile Ser Phe Ser Asp Pro Asp Asp Leu Leu Asn Phe
                  50                  55                  60

 Lys Leu Val Ile Cys Pro Asp Glu Gly Phe Tyr Lys Ser Gly Lys
                  65                  70                  75

 Phe Val Phe Ser Phe Lys Val Gly Gln Gly Tyr Pro His Asp Pro
                  80                  85                  90

 Pro Lys Val Lys Cys Glu Thr Met Val Tyr His Pro Asn Ile Asp
                  95                 100                 105

 Leu Glu Gly Asn Val Cys Leu Asn Ile Leu Arg Glu Asp Trp Lys
                 110                 115                 120

 Pro Val Leu Thr Ile Asn Ser Ile Ile Tyr Gly Leu Gln Tyr Leu
                 125                 130                 135

 Phe Leu Glu Pro Asn Pro Glu Asp Pro Leu Asn Lys Glu Ala Ala
                 140                 145                 150

 Glu Val Leu Gln Asn Asn Arg Arg Leu Phe Glu Gln Asn Val Gln
                 155                 160                 165

 Arg Ser Met Arg Gly Gly Tyr Ile Gly Ser Thr Tyr Phe Glu Arg
                 170                 175                 180

 Cys Leu Lys


<210> 803
<211> 661
<212> DNA
<213> Homo sapien

<400> 803
 ccggcggtga caacggcaac atggccctga acggagctga agtcgacgac 50

 ttctcctggg agcccccgac tgaggcggag acgaaggtgc tgcaggcgcg 100

 acgggagcgg caagatcgca tctcccggct catgggcgac tatctgctgc 150

 gcggttaccg catgctgggc gagacgtgtg cggactgcgg gacgatcctc 200

 ctccaagaca aacagcggaa aatctactgc gtggcttgtc aggaactcga 250

 ctcagacgtg gataaagata atcccgctct gaatgcccag gctgccctct 300

 cccaagctcg ggagcaccag ctggcctcag cctcagagct ccccctgggc 350

 tctcgacctg cgccccagcc cccagtacct cgtccggagc actgtgaggg 400

 agctgcagca ggactcaagg cagcccaggg gccacctgct cctgctgtgc 450

 ctccaaatac agatgtcatg gcctgcacac agacagccct cttgcagaag 500

 ctgacctggg cctctgctga actgggctcc agcacctccc tggagactag 550

 catccagctg tgtggcctta tccgcgcatg tgcggaggcc ctgcgcagcc 600

 tgcagcagct acagcactaa gagaagcccc tgagaaaaac cctctagaaa 650

 aacaaaaaaa a 661

<210> 804
<211> 199
<212> PRT
<213> Homo sapien

<400> 804
 Met Ala Leu Asn Gly Ala Glu Val Asp Asp Phe Ser Trp Glu Pro
   1               5                  10                  15

 Pro Thr Glu Ala Glu Thr Lys Val Leu Gln Ala Arg Arg Glu Arg
                  20                  25                  30

 Gln Asp Arg Ile Ser Arg Leu Met Gly Asp Tyr Leu Leu Arg Gly
                  35                  40                  45

 Tyr Arg Met Leu Gly Glu Thr Cys Ala Asp Cys Gly Thr Ile Leu
                  50                  55                  60

 Leu Gln Asp Lys Gln Arg Lys Ile Tyr Cys Val Ala Cys Gln Glu
                  65                  70                  75

 Leu Asp Ser Asp Val Asp Lys Asp Asn Pro Ala Leu Asn Ala Gln
                  80                  85                  90

 Ala Ala Leu Ser Gln Ala Arg Glu His Gln Leu Ala Ser Ala Ser
                  95                 100                 105

 Glu Leu Pro Leu Gly Ser Arg Pro Ala Pro Gln Pro Pro Val Pro
                 110                 115                 120

 Arg Pro Glu His Cys Glu Gly Ala Ala Ala Gly Leu Lys Ala Ala
                 125                 130                 135

 Gln Gly Pro Pro Ala Pro Ala Val Pro Pro Asn Thr Asp Val Met
                 140                 145                 150

 Ala Cys Thr Gln Thr Ala Leu Leu Gln Lys Leu Thr Trp Ala Ser
                 155                 160                 165

 Ala Glu Leu Gly Ser Ser Thr Ser Leu Glu Thr Ser Ile Gln Leu
                 170                 175                 180

 Cys Gly Leu Ile Arg Ala Cys Ala Glu Ala Leu Arg Ser Leu Gln
                 185                 190                 195

 Gln Leu Gln His


<210> 805
<211> 3497
<212> DNA
<213> Homo sapien

<400> 805
 cactgctcct ccggctcccg ggaagccgcg agtttccgca gggaggcggc 50

 ggcagctgcg gcggggccgg tctgtagcct ttgctgagtc aacactactc 100

 acagtgaaag tgatgccttt tctccatttg cacaacatga gtgtgacgtg 150

 gttagccaga ccaggagctc aacctcatgt agaatccagt ccactgctct 200

 gatgccgaag gggaggcaga aagtgccaca cttggatgcc cccctgggcc 250

 tgcccacctg cctctggctg gaattagccg ggctcttctt actggttccc 300

 tgggtcatgg gcctggcagg gacaggtggg cctgatggcc agggcacagg 350

 ggggccgagc tgggctgtgc acctggaaag cctggaaggt gacggggagg 400

 aagagactct ggagcagcag gcggatgcct tggcccaggc agcagggctg 450

 gtgaatgctg gacgcatcgg agagcttcag gggcactacc tctttgtcca 500

 gcctgctggg cacaggccgg ccctggaggt ggaggccatc cggcagcagg 550

 tggaggctgt gttggctggg catgaagctg tgcgctggca ctcagagcag 600

 aggctgctaa ggcgggccaa gcgcagcgtc cacttcaacg accccaagta 650

 cccgcagcaa tggcacctga ataaccgacg gagcccgggc agggacatca 700

 acgtgacggg tgtgtgggaa cgcaatgtga ctgggcgagg ggtgacggtg 750

 gtggtagtgg atgacggagt ggaacacacc atccaggaca ttgcacccaa 800

 ctatagccct gagggtagct atgacctcaa ctctaatgac cctgacccca 850

 tgccccaccc ggatgtggag aatggcaacc accatggcac gcgatgtgca 900

 ggagagatcg cggctgtgcc caacaacagc ttctgtgccg tgggcgtggc 950

 ctacgggagc cgcatcgcag gtatccgggt actggatgga cctctcacag 1000

 acagcatgga ggcagtggcg ttcaacaagc actatcagat caatgacatc 1050

 tacagctgca gctggggacc agatgacgat gggaagacag tggatggccc 1100

 ccatcagctt ggaaaggctg ccttacaaca tggggtgatt gctggtcgcc 1150

 agggctttgg gagcatcttt gtggtagcca gtggcaacgg aggccaacac 1200

 aacgacaact gcaactacga tggctacgcc aactccatct acaccgtcac 1250

 cataggagct gtggatgagg agggacgcat gcctttctat gcagaagaat 1300

 gtgcctccat gctggcagtc accttcagtg gtggggacaa gatgcttcgg 1350

 agcattgtga ccactgactg ggaccttcag aagggcactg gctgcactga 1400

 gggccacaca gggacctcag ctgcagcgcc tctggcagct ggcatgatag 1450

 ccttaatgct gcaggtgcgg ccctgcctca cgtggcgtga cgtccagcac 1500

 atcattgtct tcacagccac ccggtatgag gatcgccgtg cagagtgggt 1550

 caccaacgag gcaggcttca gccatagcca ccagcacggt ttcggcctcc 1600

 tcaacgcctg gaggctcgtg aatgcagcca agatctggac atctgtccct 1650

 tacttagcat cctacgtcag tcccgtgtta aaagaaaaca aggcgattcc 1700

 gcagtccccc cgttccctgg aggtcctgtg gaatgtcagc aggatggacc 1750

 tggagatgtc agggctgaag accctggagc atgtggcagt gacagtctcc 1800

 atcactcacc cacggcgcgg cagcttggag ctgaagctgt tctgccccag 1850

 tggcatgatg tccctcatcg gcgccccccg cagcatggac tcggatccca 1900

 acggcttcaa tgactggacc ttctccactg tgcgatgctg gggggagaga 1950

 gcccgaggga cctacaggct tgtcatcagg gatgtcgggg atgagtcatt 2000

 ccaggtcggc atcctccggc aatggcagct gaccctatat ggctctgtgt 2050

 ggagtgcagt agacatcagg gacagacaaa ggctgttaga gagtgccatg 2100

 agtggaaaat acctgcacga tgacttcgcc ctgccctgcc caccggggct 2150

 gaaaattcct gaggaagatg gttacaccat cacccccaac accctcaaga 2200

 ccctggtgct ggtaggctgt ttcaccgtct tctggactgt ttactacatg 2250

 ctggaagtat atttgagcca gaggaatgtg gcttccaatc aagtttgtag 2300

 gagtggaccc tgccactggc cccatcggag ccggaaagcc aaggaggaag 2350

 ggacagagct agaatcagtg ccactttgca gcagcaagga tccagacgaa 2400

 gtggaaacag agagcagggg ccctcccacc acctctgacc tccttgcccc 2450

 agacctgctg gagcaagggg actggagcct gtcccagaac aagagcgccc 2500

 tggactgccc tcatcagcac ctagacgtac cgcacgggaa ggaggagcag 2550

 atctgctgac ctcagggcct gacagtgtgg gacaggctct tctttcccaa 2600

 aattagggag ctcttgacag aaagcagttc tgatgcttac atctggaatc 2650

 tgaggcatcc tctgactcca ctcaaagagg gtgagggcct tcttaagata 2700

 caaatggtgg aggattgctg ccagagaagt ctggtcagag ccacagggtc 2750

 tgcctccagc caaacgggag cttttggtga gaaggtgttg gacaggggat 2800

 tggcgccccc ctttggtttg gcctccatcc tcatctctct tgggccaagc 2850

 cagctgccta ggtcccccaa gcatggggga ccccttccca catataagtt 2900

 gagaaggtgc ctgccatagc caggagcgca tctcaatgga aacatcactg 2950

 gggtcacttg ggaagaggac ttcggggtag aggctgggag gagcccctgg 3000

 acatgcctgt cctgaaagcg gctgcctcca ttatccattc ccaagatgcc 3050

 tgatcagaaa ccaaccatga atgaacccct ggctccttca ccacccccac 3100

 gattggtatg atgctgccgg cacagctggg atacacacgg ctcccccagg 3150

 cctgagctgc ttcactaggg aatcctgcgg caggactgca gagcagatgg 3200

 cagatgcaca tgttggagga gagagccttg ggagccactg ccactccagt 3250

 cctgccacca ccctgtcttc ctctgcaagt gctcagggaa atggccttcc 3300

 cgccggaggc cagctatctg cctgacaggc tgtgactctt ctctcaacct 3350

 tggccttctc ccctcttctg agctagttgg ttgaattttt tttaatgctt 3400

 aagatttgtt tttctctttt cacagcaaca ttttcttgaa tttttttctg 3450

 cacagctttt ccaaaataaa aaccttccaa acaaaaaaaa aaaaaaa 3497

<210> 806
<211> 785
<212> PRT
<213> Homo sapien

<400> 806
 Met Pro Lys Gly Arg Gln Lys Val Pro His Leu Asp Ala Pro Leu
   1               5                  10                  15

 Gly Leu Pro Thr Cys Leu Trp Leu Glu Leu Ala Gly Leu Phe Leu
                  20                  25                  30

 Leu Val Pro Trp Val Met Gly Leu Ala Gly Thr Gly Gly Pro Asp
                  35                  40                  45

 Gly Gln Gly Thr Gly Gly Pro Ser Trp Ala Val His Leu Glu Ser
                  50                  55                  60

 Leu Glu Gly Asp Gly Glu Glu Glu Thr Leu Glu Gln Gln Ala Asp
                  65                  70                  75

 Ala Leu Ala Gln Ala Ala Gly Leu Val Asn Ala Gly Arg Ile Gly
                  80                  85                  90

 Glu Leu Gln Gly His Tyr Leu Phe Val Gln Pro Ala Gly His Arg
                  95                 100                 105

 Pro Ala Leu Glu Val Glu Ala Ile Arg Gln Gln Val Glu Ala Val
                 110                 115                 120

 Leu Ala Gly His Glu Ala Val Arg Trp His Ser Glu Gln Arg Leu
                 125                 130                 135

 Leu Arg Arg Ala Lys Arg Ser Val His Phe Asn Asp Pro Lys Tyr
                 140                 145                 150

 Pro Gln Gln Trp His Leu Asn Asn Arg Arg Ser Pro Gly Arg Asp
                 155                 160                 165

 Ile Asn Val Thr Gly Val Trp Glu Arg Asn Val Thr Gly Arg Gly
                 170                 175                 180

 Val Thr Val Val Val Val Asp Asp Gly Val Glu His Thr Ile Gln
                 185                 190                 195

 Asp Ile Ala Pro Asn Tyr Ser Pro Glu Gly Ser Tyr Asp Leu Asn
                 200                 205                 210

 Ser Asn Asp Pro Asp Pro Met Pro His Pro Asp Val Glu Asn Gly
                 215                 220                 225

 Asn His His Gly Thr Arg Cys Ala Gly Glu Ile Ala Ala Val Pro
                 230                 235                 240

 Asn Asn Ser Phe Cys Ala Val Gly Val Ala Tyr Gly Ser Arg Ile
                 245                 250                 255

 Ala Gly Ile Arg Val Leu Asp Gly Pro Leu Thr Asp Ser Met Glu
                 260                 265                 270

 Ala Val Ala Phe Asn Lys His Tyr Gln Ile Asn Asp Ile Tyr Ser
                 275                 280                 285

 Cys Ser Trp Gly Pro Asp Asp Asp Gly Lys Thr Val Asp Gly Pro
                 290                 295                 300

 His Gln Leu Gly Lys Ala Ala Leu Gln His Gly Val Ile Ala Gly
                 305                 310                 315

 Arg Gln Gly Phe Gly Ser Ile Phe Val Val Ala Ser Gly Asn Gly
                 320                 325                 330

 Gly Gln His Asn Asp Asn Cys Asn Tyr Asp Gly Tyr Ala Asn Ser
                 335                 340                 345

 Ile Tyr Thr Val Thr Ile Gly Ala Val Asp Glu Glu Gly Arg Met
                 350                 355                 360

 Pro Phe Tyr Ala Glu Glu Cys Ala Ser Met Leu Ala Val Thr Phe
                 365                 370                 375

 Ser Gly Gly Asp Lys Met Leu Arg Ser Ile Val Thr Thr Asp Trp
                 380                 385                 390

 Asp Leu Gln Lys Gly Thr Gly Cys Thr Glu Gly His Thr Gly Thr
                 395                 400                 405

 Ser Ala Ala Ala Pro Leu Ala Ala Gly Met Ile Ala Leu Met Leu
                 410                 415                 420

 Gln Val Arg Pro Cys Leu Thr Trp Arg Asp Val Gln His Ile Ile
                 425                 430                 435

 Val Phe Thr Ala Thr Arg Tyr Glu Asp Arg Arg Ala Glu Trp Val
                 440                 445                 450

 Thr Asn Glu Ala Gly Phe Ser His Ser His Gln His Gly Phe Gly
                 455                 460                 465

 Leu Leu Asn Ala Trp Arg Leu Val Asn Ala Ala Lys Ile Trp Thr
                 470                 475                 480

 Ser Val Pro Tyr Leu Ala Ser Tyr Val Ser Pro Val Leu Lys Glu
                 485                 490                 495

 Asn Lys Ala Ile Pro Gln Ser Pro Arg Ser Leu Glu Val Leu Trp
                 500                 505                 510

 Asn Val Ser Arg Met Asp Leu Glu Met Ser Gly Leu Lys Thr Leu
                 515                 520                 525

 Glu His Val Ala Val Thr Val Ser Ile Thr His Pro Arg Arg Gly
                 530                 535                 540

 Ser Leu Glu Leu Lys Leu Phe Cys Pro Ser Gly Met Met Ser Leu
                 545                 550                 555

 Ile Gly Ala Pro Arg Ser Met Asp Ser Asp Pro Asn Gly Phe Asn
                 560                 565                 570

 Asp Trp Thr Phe Ser Thr Val Arg Cys Trp Gly Glu Arg Ala Arg
                 575                 580                 585

 Gly Thr Tyr Arg Leu Val Ile Arg Asp Val Gly Asp Glu Ser Phe
                 590                 595                 600

 Gln Val Gly Ile Leu Arg Gln Trp Gln Leu Thr Leu Tyr Gly Ser
                 605                 610                 615

 Val Trp Ser Ala Val Asp Ile Arg Asp Arg Gln Arg Leu Leu Glu
                 620                 625                 630

 Ser Ala Met Ser Gly Lys Tyr Leu His Asp Asp Phe Ala Leu Pro
                 635                 640                 645

 Cys Pro Pro Gly Leu Lys Ile Pro Glu Glu Asp Gly Tyr Thr Ile
                 650                 655                 660

 Thr Pro Asn Thr Leu Lys Thr Leu Val Leu Val Gly Cys Phe Thr
                 665                 670                 675

 Val Phe Trp Thr Val Tyr Tyr Met Leu Glu Val Tyr Leu Ser Gln
                 680                 685                 690

 Arg Asn Val Ala Ser Asn Gln Val Cys Arg Ser Gly Pro Cys His
                 695                 700                 705

 Trp Pro His Arg Ser Arg Lys Ala Lys Glu Glu Gly Thr Glu Leu
                 710                 715                 720

 Glu Ser Val Pro Leu Cys Ser Ser Lys Asp Pro Asp Glu Val Glu
                 725                 730                 735

 Thr Glu Ser Arg Gly Pro Pro Thr Thr Ser Asp Leu Leu Ala Pro
                 740                 745                 750

 Asp Leu Leu Glu Gln Gly Asp Trp Ser Leu Ser Gln Asn Lys Ser
                 755                 760                 765

 Ala Leu Asp Cys Pro His Gln His Leu Asp Val Pro His Gly Lys
                 770                 775                 780

 Glu Glu Gln Ile Cys
                 785

<210> 807
<211> 1910
<212> DNA
<213> Homo sapien

<400> 807
 aggtttcggc gggggctgca cgtgcgcagg ggtgtggaaa cttaccggct 50

 gagccatgga tacaccgtta aggcgcagcc gacggctggg aggcctaagg 100

 cccgaatccc ccgagagcct cacctcagtt tcgcggacga gacgggccct 150

 tgtggagttc gagtcgaacc cagaagaaac gagggagccc gggtctcctc 200

 cgagtgtgca gcgggctggc ctggggtccc ccgaaaggcc gccgaagaca 250

 agcccaggat caccccgtct gcagcagggt gcaggcttgg agtcacccca 300

 agggcagcca gagccaggcg cagcgtcccc ccagcgtcag caagacctac 350

 acctggagtc gcctcaaaga cagccagagt acagtcctga atccccacga 400

 tgtcagccga agccaagtga ggaggcacca aagtgttctc aggaccaggg 450

 agtactggcc tcggagttgg cccagaataa ggaggagctg accccggggg 500

 ccccccagca tcagctaccg ccggtcccag gatcaccaga gccttacccc 550

 ggtcagcaag ctcccggtcc ggagccctct cagccactac tggagctgac 600

 acccagggca cctggctccc cccggggtca gcatgagccg agcaagccac 650

 ctccagctgg ggagacggtg acaggcggct tcggggcaaa gaagcgaaaa 700

 ggttcttcat cccaggcccc agcgtccaag aagttgaata aagaggagct 750

 tcctgtaatc ccgaagggga agcccaaatc ggggcgagtg tggaaggacc 800

 gctccaagaa aagattctcc cagatgcttc aggacaagcc cctgcgcaca 850

 tcgtggcagc ggaagatgaa ggaacgacag gagaggaagc tggccaagga 900

 ctttgcccgt cacctggagg aggagaagga gaggcgccgc caggagaaga 950

 aacagcgccg ggctgagaac ctgaaacgcc gcctggagaa tgagcggaag 1000

 gcagaggtcg tccaagtgat ccgaaacccc gccaagctca agcgggcaaa 1050

 gaagaagcag ctgcgctcca ttgagaagcg ggacaccctg gccctgctgc 1100

 agaagcagcc gccccagcag ccggcagcca agatctgagc tcaggacggc 1150

 ccgaggcctt ccatggccaa cgaccatgtc agacacagca cctcaggccg 1200

 ctgctcagat gcctctgctg gagctggcac tccaaaccca tggctccaga 1250

 acggggaccc ccaccccgac cggggctcct cggcctttga aggcttccag 1300

 gcaggtctgt gtgggacaga agcccagagg gggcctggga cctggcagag 1350

 atgggggcgg gaagagattc agctcccatc cctccttcct ctccttctcc 1400

 aagtgccttc aaaccaagaa ctgtacattc ttctggttcc tcagtgagct 1450

 ggtgactggc aggtgactcc ctcagcagtg tatgcccttt ctcagcatcc 1500

 taggtccatc ccaggcctgg aggctgacag ttgggaatcc agcttccccc 1550

 acaccttccc aaaggctgct ctgagcacct ccacacccca ctgcctctgt 1600

 ccccagcaaa ctgaatccgg ttcctctcca cttttcaata ctgaaagatt 1650

 aaaatgggga ggttgcaggg agcagagctt ttccctagca cccactttcc 1700

 caaaccagtc tctgcagaag ccccagagaa tctaactcat gcctgtccag 1750

 tctacagcaa aaatatttat tgagtgcctg ttgcatacag gcacaatcct 1800

 aggcaccggc aaatacagac aatagaccaa agtccctgcc ctcgaggagc 1850

 tttcattctg atggagagaa aacataataa acaagcaaaa tgcaaaaaaa 1900

 aaaaaaaaaa 1910

<210> 808
<211> 360
<212> PRT
<213> Homo sapien

<400> 808
 Met Asp Thr Pro Leu Arg Arg Ser Arg Arg Leu Gly Gly Leu Arg
   1               5                  10                  15

 Pro Glu Ser Pro Glu Ser Leu Thr Ser Val Ser Arg Thr Arg Arg
                  20                  25                  30

 Ala Leu Val Glu Phe Glu Ser Asn Pro Glu Glu Thr Arg Glu Pro
                  35                  40                  45

 Gly Ser Pro Pro Ser Val Gln Arg Ala Gly Leu Gly Ser Pro Glu
                  50                  55                  60

 Arg Pro Pro Lys Thr Ser Pro Gly Ser Pro Arg Leu Gln Gln Gly
                  65                  70                  75

 Ala Gly Leu Glu Ser Pro Gln Gly Gln Pro Glu Pro Gly Ala Ala
                  80                  85                  90

 Ser Pro Gln Arg Gln Gln Asp Leu His Leu Glu Ser Pro Gln Arg
                  95                 100                 105

 Gln Pro Glu Tyr Ser Pro Glu Ser Pro Arg Cys Gln Pro Lys Pro
                 110                 115                 120

 Ser Glu Glu Ala Pro Lys Cys Ser Gln Asp Gln Gly Val Leu Ala
                 125                 130                 135

 Ser Glu Leu Ala Gln Asn Lys Glu Glu Leu Thr Pro Gly Ala Pro
                 140                 145                 150

 Gln His Gln Leu Pro Pro Val Pro Gly Ser Pro Glu Pro Tyr Pro
                 155                 160                 165

 Gly Gln Gln Ala Pro Gly Pro Glu Pro Ser Gln Pro Leu Leu Glu
                 170                 175                 180

 Leu Thr Pro Arg Ala Pro Gly Ser Pro Arg Gly Gln His Glu Pro
                 185                 190                 195

 Ser Lys Pro Pro Pro Ala Gly Glu Thr Val Thr Gly Gly Phe Gly
                 200                 205                 210

 Ala Lys Lys Arg Lys Gly Ser Ser Ser Gln Ala Pro Ala Ser Lys
                 215                 220                 225

 Lys Leu Asn Lys Glu Glu Leu Pro Val Ile Pro Lys Gly Lys Pro
                 230                 235                 240

 Lys Ser Gly Arg Val Trp Lys Asp Arg Ser Lys Lys Arg Phe Ser
                 245                 250                 255

 Gln Met Leu Gln Asp Lys Pro Leu Arg Thr Ser Trp Gln Arg Lys
                 260                 265                 270

 Met Lys Glu Arg Gln Glu Arg Lys Leu Ala Lys Asp Phe Ala Arg
                 275                 280                 285

 His Leu Glu Glu Glu Lys Glu Arg Arg Arg Gln Glu Lys Lys Gln
                 290                 295                 300

 Arg Arg Ala Glu Asn Leu Lys Arg Arg Leu Glu Asn Glu Arg Lys
                 305                 310                 315

 Ala Glu Val Val Gln Val Ile Arg Asn Pro Ala Lys Leu Lys Arg
                 320                 325                 330

 Ala Lys Lys Lys Gln Leu Arg Ser Ile Glu Lys Arg Asp Thr Leu
                 335                 340                 345

 Ala Leu Leu Gln Lys Gln Pro Pro Gln Gln Pro Ala Ala Lys Ile
                 350                 355                 360

<210> 809
<211> 4740
<212> DNA
<213> Homo sapien

<400> 809
 ttccggtttt tctcagggga cgttgaaatt atttttgtaa cgggagtcgg 50

 gagaggacgg ggcgtgcccc gcgtgcgcgc gcgtcgtcct ccccggcgct 100

 cctccacagc tcgctggctc ccgccgcgga aaggcgtcat gccgcccaaa 150

 accccccgaa aaacggccgc caccgccgcc gctgccgccg cggaaccccc 200

 ggcaccgccg ccgccgcccc ctcctgagga ggacccagag caggacagcg 250

 gcccggagga cctgcctctc gtcaggcttg agtttgaaga aacagaagaa 300

 cctgatttta ctgcattatg tcagaaatta aagataccag atcatgtcag 350

 agagagagct tggttaactt gggagaaagt ttcatctgtg gatggagtat 400

 tgggaggtta tattcaaaag aaaaaggaac tgtggggaat ctgtatcttt 450

 attgcacgag ttgacctaga tgagatgtcg ttcactttac tgagctacag 500

 aaaaacatac gaaatcagtg tccataaatt ctttaactta ctaaaagaaa 550

 ttgataccag taccaaagtt gataatgcta tgtcaagact gttgaagaag 600

 tatgatgtat tgtttgcact cttcagcaaa ttggaaagga catgtgaact 650

 tatatatttg acacaaccca gcagttcgat atctactgaa ataaattctg 700

 cattggtgct aaaagtttct tggatcacat ttttattagc taaaggggaa 750

 gtattacaaa tggaagatga tctggtgatt tcatttcagt taatgctatg 800

 tgtccttgac tattttatta aactctcacc tcccatgttg ctcaaagaac 850

 catataaaac agctgttata cccattaatg gttcacctcg aacacccagg 900

 cgaggtcaga acaggagtgc acggatagca aaacaactag aaaatgatac 950

 aagaattatt gaagttctct gtaaagaaca tgaatgtaat atagatgagg 1000

 tgaaaaatgt ttatttcaaa aattttatac cttttatgaa ttctcttgga 1050

 cttgtaacat ctaatggact tccagaggtt gaaaatcttt ctaaacgata 1100

 cgaagaaatt tatcttaaaa ataaagatct agatcgaaga ttatttttgg 1150

 atcatgataa aactcttcag actgattcta tagacagttt tgaaacacag 1200

 agaacaccac gaaaaagtaa ccttgatgaa gaggtgaata taattcctcc 1250

 acacactcca gttaggactg ttatgaacac tatccaacaa ttaatgatga 1300

 ttttaaattc tgcaagtgat caaccttcag aaaatctgat ttcctatttt 1350

 aacaactgca cagtgaatcc aaaagaaagt atactgaaaa gagtgaagga 1400

 tataggatac atctttaaag agaaatttgc taaagctgtg ggacagggtt 1450

 gtgtcgaaat tggatcacag cgatacaaac ttggagttcg cttgtattac 1500

 cgagtaatgg aatccatgct taaatcagaa gaagaacgat tatccattca 1550

 aaattttagc aaacttctga atgacaacat ttttcatatg tctttattgg 1600

 cgtgcgctct tgaggttgta atggccacat atagcagaag tacatctcag 1650

 aatcttgatt ctggaacaga tttgtctttc ccatggattc tgaatgtgct 1700

 taatttaaaa gcctttgatt tttacaaagt gatcgaaagt tttatcaaag 1750

 cagaaggcaa cttgacaaga gaaatgataa aacatttaga acgatgtgaa 1800

 catcgaatca tggaatccct tgcatggctc tcagattcac ctttatttga 1850

 tcttattaaa caatcaaagg accgagaagg accaactgat caccttgaat 1900

 ctgcttgtcc tcttaatctt cctctccaga ataatcacac tgcagcagat 1950

 atgtatcttt ctcctgtaag atctccaaag aaaaaaggtt caactacgcg 2000

 tgtaaattct actgcaaatg cagagacaca agcaacctca gccttccaga 2050

 cccagaagcc attgaaatct acctctcttt cactgtttta taaaaaagtg 2100

 tatcggctag cctatctccg gctaaataca ctttgtgaac gccttctgtc 2150

 tgagcaccca gaattagaac atatcatctg gacccttttc cagcacaccc 2200

 tgcagaatga gtatgaactc atgagagaca ggcatttgga ccaaattatg 2250

 atgtgttcca tgtatggcat atgcaaagtg aagaatatag accttaaatt 2300

 caaaatcatt gtaacagcat acaaggatct tcctcatgct gttcaggaga 2350

 cattcaaacg tgttttgatc aaagaagagg agtatgattc tattatagta 2400

 ttctataact cggtcttcat gcagagactg aaaacaaata ttttgcagta 2450

 tgcttccacc aggcccccta ccttgtcacc aatacctcac attcctcgaa 2500

 gcccttacaa gtttcctagt tcacccttac ggattcctgg agggaacatc 2550

 tatatttcac ccctgaagag tccatataaa atttcagaag gtctgccaac 2600

 accaacaaaa atgactccaa gatcaagaat cttagtatca attggtgaat 2650

 cattcgggac ttctgagaag ttccagaaaa taaatcagat ggtatgtaac 2700

 agcgaccgtg tgctcaaaag aagtgctgaa ggaagcaacc ctcctaaacc 2750

 actgaaaaaa ctacgctttg atattgaagg atcagatgaa gcagatggaa 2800

 gtaaacatct cccaggagag tccaaatttc agcagaaact ggcagaaatg 2850

 acttctactc gaacacgaat gcaaaagcag aaaatgaatg atagcatgga 2900

 tacctcaaac aaggaagaga aatgaggatc tcaggacctt ggtggacact 2950

 gtgtacacct ctggattcat tgtctctcac agatgtgact gtataacttt 3000

 cccaggttct gtttatggcc acatttaata tcttcagctc tttttgtgga 3050

 tataaaatgt gcagatgcaa ttgtttgggt gagtcctaag ccacttgaaa 3100

 tgttagtcat tgttatttat acaagattga aaatcttgtg taaatcctgc 3150

 catttaaaaa gttgtagcag attgtttcct cttccaaagt aaaattgctg 3200

 tgctttatgg atagtaagaa tggccctaga gtgggagtcc tgataaccca 3250

 ggcctgtctg actactttgc cttcttttgt agcatatagg tgatgtttgc 3300

 tcttgttttt attaatttat atgtatattt ttttaattta acatgaacac 3350

 ccttagaaaa tgtgtcctat ctatcttcca aatgcaattt gattgactgc 3400

 ccattcacca aaattatcct gaactcttct gcaaaaatgg atattattag 3450

 aaattagaaa aaaattacta attttacaca ttagatttta ttttactatt 3500

 ggaatctgat atactgtgtg cttgttttat aaaattttgc ttttaattaa 3550

 ataaaagctg gaagcaaagt ataaccatat gatactatca tactactgaa 3600

 acagatttca tacctcagaa tgtaaaagaa cttactgatt attttcttca 3650

 tccaacttat gtttttaaat gaggattatt gatagtactc ttggttttta 3700

 taccattcag atcactgaat ttataaagta cccatctagt acttgaaaaa 3750

 gtaaagtgtt ctgccagatc ttaggtatag aggaccctaa cacagtatat 3800

 cccaagtgca ctttctaatg tttctgggtc ctgaagaatt aagatacaaa 3850

 ttaattttac tccataaaca gactgttaat tataggagcc ttaatttttt 3900

 tttcatagag atttgtctaa ttgcatctca aaattattct gccctcctta 3950

 atttgggaag gtttgtgttt tctctggaat ggtacatgtc ttccatgtat 4000

 cttttgaact ggcaattgtc tatttatctt ttattttttt aagtcagtat 4050

 ggtctaacac tggcatgttc aaagccacat tatttctagt ccaaaattac 4100

 aagtaatcaa gggtcattat gggttaggca ttaatgtttc tatctgattt 4150

 tgtgcaaaag cttcaaatta aaacagctgc attagaaaaa gaggcgcttc 4200

 tcccctcccc tacacctaaa ggtgtattta aactatcttg tgtgattaac 4250

 ttatttagag atgctgtaac ttaaaatagg ggatatttaa ggtagcttca 4300

 gctagctttt aggaaaatca ctttgtctaa ctcagaatta tttttaaaaa 4350

 gaaatctggt cttgttagaa aacaaaattt tattttgtgc tcatttaagt 4400

 ttcaaactta ctattttgac agttattttg ataacaatga cactagaaaa 4450

 cttgactcca tttcatcatt gtttctgcat gaatatcata caaatcagtt 4500

 agtttttagg tcaagggctt actatttctg ggtcttttgc tactaagttc 4550

 acattagaat tagtgccaga attttaggaa cttcagagat cgtgtattga 4600

 gatttcttaa ataatgcttc agatattatt gctttattgc ttttttgtat 4650

 tggttaaaac tgtacattta aaattgctat gttactattt tctacaatta 4700

 atagtttgtc tattttaaaa taaattagtt gttaagagtc 4740

<210> 810
<211> 928
<212> PRT
<213> Homo sapien

<400> 810
 Met Pro Pro Lys Thr Pro Arg Lys Thr Ala Ala Thr Ala Ala Ala
   1               5                  10                  15

 Ala Ala Ala Glu Pro Pro Ala Pro Pro Pro Pro Pro Pro Pro Glu
                  20                  25                  30

 Glu Asp Pro Glu Gln Asp Ser Gly Pro Glu Asp Leu Pro Leu Val
                  35                  40                  45

 Arg Leu Glu Phe Glu Glu Thr Glu Glu Pro Asp Phe Thr Ala Leu
                  50                  55                  60

 Cys Gln Lys Leu Lys Ile Pro Asp His Val Arg Glu Arg Ala Trp
                  65                  70                  75

 Leu Thr Trp Glu Lys Val Ser Ser Val Asp Gly Val Leu Gly Gly
                  80                  85                  90

 Tyr Ile Gln Lys Lys Lys Glu Leu Trp Gly Ile Cys Ile Phe Ile
                  95                 100                 105

 Ala Arg Val Asp Leu Asp Glu Met Ser Phe Thr Leu Leu Ser Tyr
                 110                 115                 120

 Arg Lys Thr Tyr Glu Ile Ser Val His Lys Phe Phe Asn Leu Leu
                 125                 130                 135

 Lys Glu Ile Asp Thr Ser Thr Lys Val Asp Asn Ala Met Ser Arg
                 140                 145                 150

 Leu Leu Lys Lys Tyr Asp Val Leu Phe Ala Leu Phe Ser Lys Leu
                 155                 160                 165

 Glu Arg Thr Cys Glu Leu Ile Tyr Leu Thr Gln Pro Ser Ser Ser
                 170                 175                 180

 Ile Ser Thr Glu Ile Asn Ser Ala Leu Val Leu Lys Val Ser Trp
                 185                 190                 195

 Ile Thr Phe Leu Leu Ala Lys Gly Glu Val Leu Gln Met Glu Asp
                 200                 205                 210

 Asp Leu Val Ile Ser Phe Gln Leu Met Leu Cys Val Leu Asp Tyr
                 215                 220                 225

 Phe Ile Lys Leu Ser Pro Pro Met Leu Leu Lys Glu Pro Tyr Lys
                 230                 235                 240

 Thr Ala Val Ile Pro Ile Asn Gly Ser Pro Arg Thr Pro Arg Arg
                 245                 250                 255

 Gly Gln Asn Arg Ser Ala Arg Ile Ala Lys Gln Leu Glu Asn Asp
                 260                 265                 270

 Thr Arg Ile Ile Glu Val Leu Cys Lys Glu His Glu Cys Asn Ile
                 275                 280                 285

 Asp Glu Val Lys Asn Val Tyr Phe Lys Asn Phe Ile Pro Phe Met
                 290                 295                 300

 Asn Ser Leu Gly Leu Val Thr Ser Asn Gly Leu Pro Glu Val Glu
                 305                 310                 315

 Asn Leu Ser Lys Arg Tyr Glu Glu Ile Tyr Leu Lys Asn Lys Asp
                 320                 325                 330

 Leu Asp Arg Arg Leu Phe Leu Asp His Asp Lys Thr Leu Gln Thr
                 335                 340                 345

 Asp Ser Ile Asp Ser Phe Glu Thr Gln Arg Thr Pro Arg Lys Ser
                 350                 355                 360

 Asn Leu Asp Glu Glu Val Asn Ile Ile Pro Pro His Thr Pro Val
                 365                 370                 375

 Arg Thr Val Met Asn Thr Ile Gln Gln Leu Met Met Ile Leu Asn
                 380                 385                 390

 Ser Ala Ser Asp Gln Pro Ser Glu Asn Leu Ile Ser Tyr Phe Asn
                 395                 400                 405

 Asn Cys Thr Val Asn Pro Lys Glu Ser Ile Leu Lys Arg Val Lys
                 410                 415                 420

 Asp Ile Gly Tyr Ile Phe Lys Glu Lys Phe Ala Lys Ala Val Gly
                 425                 430                 435

 Gln Gly Cys Val Glu Ile Gly Ser Gln Arg Tyr Lys Leu Gly Val
                 440                 445                 450

 Arg Leu Tyr Tyr Arg Val Met Glu Ser Met Leu Lys Ser Glu Glu
                 455                 460                 465

 Glu Arg Leu Ser Ile Gln Asn Phe Ser Lys Leu Leu Asn Asp Asn
                 470                 475                 480

 Ile Phe His Met Ser Leu Leu Ala Cys Ala Leu Glu Val Val Met
                 485                 490                 495

 Ala Thr Tyr Ser Arg Ser Thr Ser Gln Asn Leu Asp Ser Gly Thr
                 500                 505                 510

 Asp Leu Ser Phe Pro Trp Ile Leu Asn Val Leu Asn Leu Lys Ala
                 515                 520                 525

 Phe Asp Phe Tyr Lys Val Ile Glu Ser Phe Ile Lys Ala Glu Gly
                 530                 535                 540

 Asn Leu Thr Arg Glu Met Ile Lys His Leu Glu Arg Cys Glu His
                 545                 550                 555

 Arg Ile Met Glu Ser Leu Ala Trp Leu Ser Asp Ser Pro Leu Phe
                 560                 565                 570

 Asp Leu Ile Lys Gln Ser Lys Asp Arg Glu Gly Pro Thr Asp His
                 575                 580                 585

 Leu Glu Ser Ala Cys Pro Leu Asn Leu Pro Leu Gln Asn Asn His
                 590                 595                 600

 Thr Ala Ala Asp Met Tyr Leu Ser Pro Val Arg Ser Pro Lys Lys
                 605                 610                 615

 Lys Gly Ser Thr Thr Arg Val Asn Ser Thr Ala Asn Ala Glu Thr
                 620                 625                 630

 Gln Ala Thr Ser Ala Phe Gln Thr Gln Lys Pro Leu Lys Ser Thr
                 635                 640                 645

 Ser Leu Ser Leu Phe Tyr Lys Lys Val Tyr Arg Leu Ala Tyr Leu
                 650                 655                 660

 Arg Leu Asn Thr Leu Cys Glu Arg Leu Leu Ser Glu His Pro Glu
                 665                 670                 675

 Leu Glu His Ile Ile Trp Thr Leu Phe Gln His Thr Leu Gln Asn
                 680                 685                 690

 Glu Tyr Glu Leu Met Arg Asp Arg His Leu Asp Gln Ile Met Met
                 695                 700                 705

 Cys Ser Met Tyr Gly Ile Cys Lys Val Lys Asn Ile Asp Leu Lys
                 710                 715                 720

 Phe Lys Ile Ile Val Thr Ala Tyr Lys Asp Leu Pro His Ala Val
                 725                 730                 735

 Gln Glu Thr Phe Lys Arg Val Leu Ile Lys Glu Glu Glu Tyr Asp
                 740                 745                 750

 Ser Ile Ile Val Phe Tyr Asn Ser Val Phe Met Gln Arg Leu Lys
                 755                 760                 765

 Thr Asn Ile Leu Gln Tyr Ala Ser Thr Arg Pro Pro Thr Leu Ser
                 770                 775                 780

 Pro Ile Pro His Ile Pro Arg Ser Pro Tyr Lys Phe Pro Ser Ser
                 785                 790                 795

 Pro Leu Arg Ile Pro Gly Gly Asn Ile Tyr Ile Ser Pro Leu Lys
                 800                 805                 810

 Ser Pro Tyr Lys Ile Ser Glu Gly Leu Pro Thr Pro Thr Lys Met
                 815                 820                 825

 Thr Pro Arg Ser Arg Ile Leu Val Ser Ile Gly Glu Ser Phe Gly
                 830                 835                 840

 Thr Ser Glu Lys Phe Gln Lys Ile Asn Gln Met Val Cys Asn Ser
                 845                 850                 855

 Asp Arg Val Leu Lys Arg Ser Ala Glu Gly Ser Asn Pro Pro Lys
                 860                 865                 870

 Pro Leu Lys Lys Leu Arg Phe Asp Ile Glu Gly Ser Asp Glu Ala
                 875                 880                 885

 Asp Gly Ser Lys His Leu Pro Gly Glu Ser Lys Phe Gln Gln Lys
                 890                 895                 900

 Leu Ala Glu Met Thr Ser Thr Arg Thr Arg Met Gln Lys Gln Lys
                 905                 910                 915

 Met Asn Asp Ser Met Asp Thr Ser Asn Lys Glu Glu Lys
                 920                 925

<210> 811
<211> 3630
<212> DNA
<213> Homo sapien

<400> 811
 ggtattccag aagtgtttga ggatcccttc catgaaggaa gagaggaaag 50

 tttttaagta aacctcccac tcccatgtgt cttcagcttt cttttgcaaa 100

 ggagaaaatc cttgaagttt ggtaaagacc gagttagtct atctctcttt 150

 gcctatctcg agttgggctg gggagaggag gagataggtt cttttgtctt 200

 tttctgtctt ctcccttccc cacttccttc cctccagtcc ccactcactc 250

 acatgcacac actaaccttg gagccgatgg gattgagtga ctggcacttg 300

 ggaccacaga gaaatgtcag agtgtttggt tacagactca aggaaacctc 350

 tcattttaga gtgctcattt ggttttgagc aaaattttgg actgtgaagc 400

 aaggcattgg tgaagacaaa atggcctcgc cggctgacag ctgtatccag 450

 ttcacccgcc atgccagtga tgttcttctc aaccttaatc gtctccggag 500

 tcgagacatc ttgactgatg ttgtcattgt tgtgagccgt gagcagttta 550

 gagcccataa aacggtcctc atggcctgca gtggcctgtt ctatagcatc 600

 tttacagacc agttgaaatg caaccttagt gtgatcaatc tagatcctga 650

 gatcaaccct gagggattct gcatcctcct ggacttcatg tacacatctc 700

 ggctcaattt gcgggagggc aacatcatgg ctgtgatggc cacggctatg 750

 tacctgcaga tggagcatgt tgtggacact tgccggaagt ttattaaggc 800

 cagtgaagca gagatggttt ctgccatcaa gcctcctcgt gaagagttcc 850

 tcaacagccg gatgctgatg ccccaagaca tcatggccta tcggggtcgt 900

 gaggtggtgg agaacaacct gccactgagg agcgcccctg ggtgtgagag 950

 cagagccttt gcccccagcc tgtacagtgg cctgtccaca ccgccagcct 1000

 cttattccat gtacagccac ctccctgtca gcagcctcct cttctccgat 1050

 gaggagtttc gggatgtccg gatgcctgtg gccaacccct tccccaagga 1100

 gcgggcactc ccatgtgata gtgccaggcc agtccctggt gagtacagcc 1150

 ggccgacttt ggaggtgtcc cccaatgtgt gccacagcaa tatctattca 1200

 cccaaggaaa caatcccaga agaggcacga agtgatatgc actacagtgt 1250

 ggctgagggc ctcaaacctg ctgccccctc agcccgaaat gccccctact 1300

 tcccttgtga caaggccagc aaagaagaag agagaccctc ctcggaagat 1350

 gagattgccc tgcatttcga gccccccaat gcacccctga accggaaggg 1400

 tctggttagt ccacagagcc cccagaaatc tgactgccag cccaactcgc 1450

 ccacagagtc ctgcagcagt aagaatgcct gcatcctcca ggcttctggc 1500

 tcccctccag ccaagagccc cactgacccc aaagcctgca actggaagaa 1550

 atacaagttc atcgtgctca acagcctcaa ccagaatgcc aaaccagagg 1600

 ggcctgagca ggctgagctg ggccgccttt ccccacgagc ctacacggcc 1650

 ccacctgcct gccagccacc catggagcct gagaaccttg acctccagtc 1700

 cccaaccaag ctgagtgcca gcggggagga ctccaccatc ccacaagcca 1750

 gccggctcaa taacatcgtt aacaggtcca tgacgggctc tccccgcagc 1800

 agcagcgaga gccactcacc actctacatg caccccccga agtgcacgtc 1850

 ctgcggctct cagtccccac agcatgcaga gatgtgcctc cacaccgctg 1900

 gccccacgtt ccctgaggag atgggagaga cccagtctga gtactcagat 1950

 tctagctgtg agaacggggc cttcttctgc aatgagtgtg actgccgctt 2000

 ctctgaggag gcctcactca agaggcacac gctgcagacc cacagtgaca 2050

 aaccctacaa gtgtgaccgc tgccaggcct ccttccgcta caagggcaac 2100

 ctcgccagcc acaagaccgt ccataccggt gagaaaccct atcgttgcaa 2150

 catctgtggg gcccagttca accggccagc caacctgaaa acccacactc 2200

 gaattcactc tggagagaag ccctacaaat gcgaaacctg cggagccaga 2250

 tttgtacagg tggcccacct ccgtgcccat gtgcttatcc acactggtga 2300

 gaagccctat ccctgtgaaa tctgtggcac ccgtttccgg caccttcaga 2350

 ctctgaagag ccacctgcga atccacacag gagagaaacc ttaccattgt 2400

 gagaagtgta acctgcattt ccgtcacaaa agccagctgc gacttcactt 2450

 gcgccagaag catggcgcca tcaccaacac caaggtgcaa taccgcgtgt 2500

 cagccactga cctgcctccg gagctcccca aagcctgctg aagcatggag 2550

 tgttgatgct ttcgtctcca gccccttctc agaatctacc caaaggatac 2600

 tgtaacactt tacaatgttc atcccatgat gtagtgcctc tttcatccac 2650

 tagtgcaaat catagctggg ggttgggggt ggtgggggtc ggggcctggg 2700

 ggactgggag ccgcagcagc tccccctccc ccactgccat aaaacattaa 2750

 gaaaatcata ttgcttcttc tcctatgtgt aaggtgaacc atgtcagcaa 2800

 aaagcaaaat cattttatat gtcaaagcag gggagtatgc aaaagttctg 2850

 acttgacttt agtctgcaaa atgaggaatg tatatgtttt gtgggaacag 2900

 atgtttcttt tgtatgtaaa tgtgcattct tttaaaagac aagacttcag 2950

 tatgttgtca aagagagggc tttaattttt ttaaccaaag gtgaaggaat 3000

 atatggcaga gttgtaaata tataaatata tatatatata aaataaatat 3050

 atataaacct aacaaagata tattaaaaat ataaaactgc gttaaaggct 3100

 cgattttgta tctgcaggca gacacggatc tgagaatctt tattgagaaa 3150

 gagcacttaa gagaatattt taagtattgc atctgtataa gtaagaaaat 3200

 attttgtcta aaatgcctca gtgtatttgt atttttttgc aagtgaaggt 3250

 ttacaattta caaagtgtgt attaaaaaaa acaaaaagaa caaaaaaatc 3300

 tgcagaagga aaaatgtgta attttgttct agttttcagt ttgtatatac 3350

 ccgtacaacg tgtcctcacg gtgccttttt tcacggaagt tttcaatgat 3400

 gggcgagcgt gcaccatccc tttttgaagt gtaggcagac acagggactt 3450

 gaagttgtta ctaactaaac tctctttggg aatgtttgtc tcatcccatt 3500

 ctgcgtcatg cttgtgttat aactactccg gagacagggt ttggctgtgt 3550

 ctaaactgca ttaccgcgtt gtaaaatata gctgtacaaa tataagaata 3600

 aaatgttgaa aagtcaaact ggaaaaaaaa 3630

<210> 812
<211> 706
<212> PRT
<213> Homo sapien

<400> 812
 Met Ala Ser Pro Ala Asp Ser Cys Ile Gln Phe Thr Arg His Ala
   1               5                  10                  15

 Ser Asp Val Leu Leu Asn Leu Asn Arg Leu Arg Ser Arg Asp Ile
                  20                  25                  30

 Leu Thr Asp Val Val Ile Val Val Ser Arg Glu Gln Phe Arg Ala
                  35                  40                  45

 His Lys Thr Val Leu Met Ala Cys Ser Gly Leu Phe Tyr Ser Ile
                  50                  55                  60

 Phe Thr Asp Gln Leu Lys Cys Asn Leu Ser Val Ile Asn Leu Asp
                  65                  70                  75

 Pro Glu Ile Asn Pro Glu Gly Phe Cys Ile Leu Leu Asp Phe Met
                  80                  85                  90

 Tyr Thr Ser Arg Leu Asn Leu Arg Glu Gly Asn Ile Met Ala Val
                  95                 100                 105

 Met Ala Thr Ala Met Tyr Leu Gln Met Glu His Val Val Asp Thr
                 110                 115                 120

 Cys Arg Lys Phe Ile Lys Ala Ser Glu Ala Glu Met Val Ser Ala
                 125                 130                 135

 Ile Lys Pro Pro Arg Glu Glu Phe Leu Asn Ser Arg Met Leu Met
                 140                 145                 150

 Pro Gln Asp Ile Met Ala Tyr Arg Gly Arg Glu Val Val Glu Asn
                 155                 160                 165

 Asn Leu Pro Leu Arg Ser Ala Pro Gly Cys Glu Ser Arg Ala Phe
                 170                 175                 180

 Ala Pro Ser Leu Tyr Ser Gly Leu Ser Thr Pro Pro Ala Ser Tyr
                 185                 190                 195

 Ser Met Tyr Ser His Leu Pro Val Ser Ser Leu Leu Phe Ser Asp
                 200                 205                 210

 Glu Glu Phe Arg Asp Val Arg Met Pro Val Ala Asn Pro Phe Pro
                 215                 220                 225

 Lys Glu Arg Ala Leu Pro Cys Asp Ser Ala Arg Pro Val Pro Gly
                 230                 235                 240

 Glu Tyr Ser Arg Pro Thr Leu Glu Val Ser Pro Asn Val Cys His
                 245                 250                 255

 Ser Asn Ile Tyr Ser Pro Lys Glu Thr Ile Pro Glu Glu Ala Arg
                 260                 265                 270

 Ser Asp Met His Tyr Ser Val Ala Glu Gly Leu Lys Pro Ala Ala
                 275                 280                 285

 Pro Ser Ala Arg Asn Ala Pro Tyr Phe Pro Cys Asp Lys Ala Ser
                 290                 295                 300

 Lys Glu Glu Glu Arg Pro Ser Ser Glu Asp Glu Ile Ala Leu His
                 305                 310                 315

 Phe Glu Pro Pro Asn Ala Pro Leu Asn Arg Lys Gly Leu Val Ser
                 320                 325                 330

 Pro Gln Ser Pro Gln Lys Ser Asp Cys Gln Pro Asn Ser Pro Thr
                 335                 340                 345

 Glu Ser Cys Ser Ser Lys Asn Ala Cys Ile Leu Gln Ala Ser Gly
                 350                 355                 360

 Ser Pro Pro Ala Lys Ser Pro Thr Asp Pro Lys Ala Cys Asn Trp
                 365                 370                 375

 Lys Lys Tyr Lys Phe Ile Val Leu Asn Ser Leu Asn Gln Asn Ala
                 380                 385                 390

 Lys Pro Glu Gly Pro Glu Gln Ala Glu Leu Gly Arg Leu Ser Pro
                 395                 400                 405

 Arg Ala Tyr Thr Ala Pro Pro Ala Cys Gln Pro Pro Met Glu Pro
                 410                 415                 420

 Glu Asn Leu Asp Leu Gln Ser Pro Thr Lys Leu Ser Ala Ser Gly
                 425                 430                 435

 Glu Asp Ser Thr Ile Pro Gln Ala Ser Arg Leu Asn Asn Ile Val
                 440                 445                 450

 Asn Arg Ser Met Thr Gly Ser Pro Arg Ser Ser Ser Glu Ser His
                 455                 460                 465

 Ser Pro Leu Tyr Met His Pro Pro Lys Cys Thr Ser Cys Gly Ser
                 470                 475                 480

 Gln Ser Pro Gln His Ala Glu Met Cys Leu His Thr Ala Gly Pro
                 485                 490                 495

 Thr Phe Pro Glu Glu Met Gly Glu Thr Gln Ser Glu Tyr Ser Asp
                 500                 505                 510

 Ser Ser Cys Glu Asn Gly Ala Phe Phe Cys Asn Glu Cys Asp Cys
                 515                 520                 525

 Arg Phe Ser Glu Glu Ala Ser Leu Lys Arg His Thr Leu Gln Thr
                 530                 535                 540

 His Ser Asp Lys Pro Tyr Lys Cys Asp Arg Cys Gln Ala Ser Phe
                 545                 550                 555

 Arg Tyr Lys Gly Asn Leu Ala Ser His Lys Thr Val His Thr Gly
                 560                 565                 570

 Glu Lys Pro Tyr Arg Cys Asn Ile Cys Gly Ala Gln Phe Asn Arg
                 575                 580                 585

 Pro Ala Asn Leu Lys Thr His Thr Arg Ile His Ser Gly Glu Lys
                 590                 595                 600

 Pro Tyr Lys Cys Glu Thr Cys Gly Ala Arg Phe Val Gln Val Ala
                 605                 610                 615

 His Leu Arg Ala His Val Leu Ile His Thr Gly Glu Lys Pro Tyr
                 620                 625                 630

 Pro Cys Glu Ile Cys Gly Thr Arg Phe Arg His Leu Gln Thr Leu
                 635                 640                 645

 Lys Ser His Leu Arg Ile His Thr Gly Glu Lys Pro Tyr His Cys
                 650                 655                 660

 Glu Lys Cys Asn Leu His Phe Arg His Lys Ser Gln Leu Arg Leu
                 665                 670                 675

 His Leu Arg Gln Lys His Gly Ala Ile Thr Asn Thr Lys Val Gln
                 680                 685                 690

 Tyr Arg Val Ser Ala Thr Asp Leu Pro Pro Glu Leu Pro Lys Ala
                 695                 700                 705

 Cys


<210> 813
<211> 2324
<212> DNA
<213> Homo sapien

<400> 813
 cattttgtgg gtggggcttc aggtgccacc cagctgaagg atggccaccc 50

 ctgtggtcac caagacagcc tggaagttgc aagagatcgt cgcgcatgcc 100

 agcaacgtgt cctcactggt gctgggcaaa gcctccgggc ggctgctggc 150

 tacaggcggg gatgactgcc gcgtcaacct gtggtccatc aacaagccca 200

 actgcatcat gagcctgacg ggccacacat ccccagtgga gagcgtccgc 250

 ctcaacaccc ccgaggagct catcgtggcc ggctctcagt cgggctccat 300

 ccgtgtctgg gacctggaag ctgccaaaat tcttcgcaca ctcatgggac 350

 tcaaagccaa catctgcagc ctggatttcc acccgtacgg cgagtttgta 400

 gcctctggtt cccaggacac aaacatcaag ctctgggaca tcaggaggaa 450

 aggctgtgtc ttccgataca gggggcacag ccaggccgtg cggtgtctcc 500

 ggttcagccc cgatgggaag tggttggcgt cggccgcaga tgaccacacc 550

 gtgaagctct gggatctcac tgccggcaag atgatgtctg agttccctgg 600

 tcacacgggg cctgtcaacg tggtcgagtt tcaccccaac gagtacctcc 650

 tggcctccgg cagctctgac gggacaatcc gcttctggga cctggagaag 700

 ttccaggtgg tgagccgcat cgaaggggag cctgggcccg tcaggagcgt 750

 cctcttcaac ccagacggct gctgcctgta cagcggctgc caggactcac 800

 tgcgtgtcta cggctgggaa cctgagcggt gctttgatgt ggtcctcgtc 850

 aactggggca aggtggccga cctggccatc tgcaatgacc agttgatagg 900

 tgtggccttc tcccagagca acgtctcctc ctacgtggtg gatctgacgc 950

 gtgtcaccag gactggcacg gtggcccggg accctgtgca ggaccaccgg 1000

 cccctggcac agccactgcc caaccccagc gcccccctcc ggcgcatcta 1050

 tgagcggccc agcacaacct gcagcaagcc tcagagggtg aagcagaact 1100

 cagagagcga gcgccgcagc cccagcagcg aggatgaccg ggacgagcgc 1150

 gagtcccgcg cggagatcca gaacgccgag gactacaacg agatcttcca 1200

 gcccaagaac agcatcagtc ggacgccacc ccggagaagt gagcccttcc 1250

 ctgcaccccc agaggacgac gcagccacag caaaggaggc agcaaagccc 1300

 agccctgcca tggatgtgca gttcccggtg ccaaatctgg aggtcctgcc 1350

 ccggccccca gtggttgctt ccacacctgc acccaaggct gagcctgcca 1400

 tcatccctgc cacccggaac gagcccatcg ggctgaaggc ctccgacttc 1450

 ctgcccgccg tgaagatccc ccagcaggcc gagctggtgg acgaggatgc 1500

 catgtcacag atccgcaaag gccacgacac catgtgtgtg gtgctcacca 1550

 gccgccacaa gaacctggac actgtgcggg ctgtgtggac catgggcgac 1600

 atcaagacgt cggtggactc cgctgtggcc atcaacgacc tgtcggtggt 1650

 ggtggacctc ctgaacatcg tcaaccagaa agcctccctg tggaagctgg 1700

 acctgtgcac caccgtcctg ccacagattg agaagcttct gcagagcaag 1750

 tatgagagct acgtccagac gggctgcacc tccctgaagc tgatcctgca 1800

 gcggtttctg cccctcatca cagacatgct ggcggcccca ccctctgtgg 1850

 gtgtggatat cagcagggag gagaggctgc ataagtgccg gctctgctac 1900

 aagcagctta agagcatcag cggcctggtc aagagcaagt caggcctgag 1950

 cggccgccat ggcagtacct tccgcgagct gcacctgctc atggccagtc 2000

 tggactgagg aaagcagtgg gcaggggcgc tcggcagccc acagggcctg 2050

 gcctcagccc ccactcctgt tccttgtgca cccactggcc catgagcctc 2100

 tgcctggccc ctgctgctgt cctgtggccg tcctggagga ggtgatgctg 2150

 gtccctggcc acctctacag ccctgaactc ttgagacaac tctctccagc 2200

 aatagctgcc cagctttgcc caactgttgc ttcttggggc agcgaactga 2250

 gccctggggc tgctgctgta atttataagg caaattttat taaatttgta 2300

 actattaaaa aaaaaaaaaa aaaa 2324

<210> 814
<211> 655
<212> PRT
<213> Homo sapien

<400> 814
 Met Ala Thr Pro Val Val Thr Lys Thr Ala Trp Lys Leu Gln Glu
   1               5                  10                  15

 Ile Val Ala His Ala Ser Asn Val Ser Ser Leu Val Leu Gly Lys
                  20                  25                  30

 Ala Ser Gly Arg Leu Leu Ala Thr Gly Gly Asp Asp Cys Arg Val
                  35                  40                  45

 Asn Leu Trp Ser Ile Asn Lys Pro Asn Cys Ile Met Ser Leu Thr
                  50                  55                  60

 Gly His Thr Ser Pro Val Glu Ser Val Arg Leu Asn Thr Pro Glu
                  65                  70                  75

 Glu Leu Ile Val Ala Gly Ser Gln Ser Gly Ser Ile Arg Val Trp
                  80                  85                  90

 Asp Leu Glu Ala Ala Lys Ile Leu Arg Thr Leu Met Gly Leu Lys
                  95                 100                 105

 Ala Asn Ile Cys Ser Leu Asp Phe His Pro Tyr Gly Glu Phe Val
                 110                 115                 120

 Ala Ser Gly Ser Gln Asp Thr Asn Ile Lys Leu Trp Asp Ile Arg
                 125                 130                 135

 Arg Lys Gly Cys Val Phe Arg Tyr Arg Gly His Ser Gln Ala Val
                 140                 145                 150

 Arg Cys Leu Arg Phe Ser Pro Asp Gly Lys Trp Leu Ala Ser Ala
                 155                 160                 165

 Ala Asp Asp His Thr Val Lys Leu Trp Asp Leu Thr Ala Gly Lys
                 170                 175                 180

 Met Met Ser Glu Phe Pro Gly His Thr Gly Pro Val Asn Val Val
                 185                 190                 195

 Glu Phe His Pro Asn Glu Tyr Leu Leu Ala Ser Gly Ser Ser Asp
                 200                 205                 210

 Gly Thr Ile Arg Phe Trp Asp Leu Glu Lys Phe Gln Val Val Ser
                 215                 220                 225

 Arg Ile Glu Gly Glu Pro Gly Pro Val Arg Ser Val Leu Phe Asn
                 230                 235                 240

 Pro Asp Gly Cys Cys Leu Tyr Ser Gly Cys Gln Asp Ser Leu Arg
                 245                 250                 255

 Val Tyr Gly Trp Glu Pro Glu Arg Cys Phe Asp Val Val Leu Val
                 260                 265                 270

 Asn Trp Gly Lys Val Ala Asp Leu Ala Ile Cys Asn Asp Gln Leu
                 275                 280                 285

 Ile Gly Val Ala Phe Ser Gln Ser Asn Val Ser Ser Tyr Val Val
                 290                 295                 300

 Asp Leu Thr Arg Val Thr Arg Thr Gly Thr Val Ala Arg Asp Pro
                 305                 310                 315

 Val Gln Asp His Arg Pro Leu Ala Gln Pro Leu Pro Asn Pro Ser
                 320                 325                 330

 Ala Pro Leu Arg Arg Ile Tyr Glu Arg Pro Ser Thr Thr Cys Ser
                 335                 340                 345

 Lys Pro Gln Arg Val Lys Gln Asn Ser Glu Ser Glu Arg Arg Ser
                 350                 355                 360

 Pro Ser Ser Glu Asp Asp Arg Asp Glu Arg Glu Ser Arg Ala Glu
                 365                 370                 375

 Ile Gln Asn Ala Glu Asp Tyr Asn Glu Ile Phe Gln Pro Lys Asn
                 380                 385                 390

 Ser Ile Ser Arg Thr Pro Pro Arg Arg Ser Glu Pro Phe Pro Ala
                 395                 400                 405

 Pro Pro Glu Asp Asp Ala Ala Thr Ala Lys Glu Ala Ala Lys Pro
                 410                 415                 420

 Ser Pro Ala Met Asp Val Gln Phe Pro Val Pro Asn Leu Glu Val
                 425                 430                 435

 Leu Pro Arg Pro Pro Val Val Ala Ser Thr Pro Ala Pro Lys Ala
                 440                 445                 450

 Glu Pro Ala Ile Ile Pro Ala Thr Arg Asn Glu Pro Ile Gly Leu
                 455                 460                 465

 Lys Ala Ser Asp Phe Leu Pro Ala Val Lys Ile Pro Gln Gln Ala
                 470                 475                 480

 Glu Leu Val Asp Glu Asp Ala Met Ser Gln Ile Arg Lys Gly His
                 485                 490                 495

 Asp Thr Met Cys Val Val Leu Thr Ser Arg His Lys Asn Leu Asp
                 500                 505                 510

 Thr Val Arg Ala Val Trp Thr Met Gly Asp Ile Lys Thr Ser Val
                 515                 520                 525

 Asp Ser Ala Val Ala Ile Asn Asp Leu Ser Val Val Val Asp Leu
                 530                 535                 540

 Leu Asn Ile Val Asn Gln Lys Ala Ser Leu Trp Lys Leu Asp Leu
                 545                 550                 555

 Cys Thr Thr Val Leu Pro Gln Ile Glu Lys Leu Leu Gln Ser Lys
                 560                 565                 570

 Tyr Glu Ser Tyr Val Gln Thr Gly Cys Thr Ser Leu Lys Leu Ile
                 575                 580                 585

 Leu Gln Arg Phe Leu Pro Leu Ile Thr Asp Met Leu Ala Ala Pro
                 590                 595                 600

 Pro Ser Val Gly Val Asp Ile Ser Arg Glu Glu Arg Leu His Lys
                 605                 610                 615

 Cys Arg Leu Cys Tyr Lys Gln Leu Lys Ser Ile Ser Gly Leu Val
                 620                 625                 630

 Lys Ser Lys Ser Gly Leu Ser Gly Arg His Gly Ser Thr Phe Arg
                 635                 640                 645

 Glu Leu His Leu Leu Met Ala Ser Leu Asp
                 650                 655

<210> 815
<211> 1347
<212> DNA
<213> Homo sapien

<400> 815
 gtggacggag aaagtgaaag gtgaggcacg gccctgcaga ttttccagcg 50

 gatcccccgg tggcctcatg tcgcgcagtg gaaccgatcc tcagcaacgc 100

 cagcaggcgt cagaggcgga cgccgcagca gcaaccttcc gggcaaacga 150

 ccatcagcat atccgctaca acccgctgca ggatgagtgg gtgctggtgt 200

 cagctcaccg catgaagcgg ccctggcagg gtcaagtgga gccccagctt 250

 ctgaagacag tgccccgcca tgaccctctc aaccctctgt gtcctggggc 300

 catccgagcc aacggagagg tgaatcccca gtacgatagc accttcctgt 350

 ttgacaacga cttcccagct ctgcagcctg atgcccccag tccaggaccc 400

 agtgatcatc cccttttcca agcaaagtct gctcgaggag tctgtaaggt 450

 catgtgcttc cacccctggt cggatgtaac gctgccactc atgtcggtcc 500

 ctgagatccg ggctgttgtt gatgcatggg cctcagtcac agaggagctg 550

 ggtgcccagt acccttgggt gcagatcttt gaaaacaaag gtgccatgat 600

 gggctgttct aacccccacc cccactgcca ggtatgggcc agcagtttcc 650

 tgccagatat tgcccagcgt gaggagcgat ctcagcaggc ctataagagt 700

 cagcatggag agcccctgct aatggagtac agccgccagg agctactcag 750

 gaaggaacgt ctggtcctaa ccagtgagca ctggttagta ctggtcccct 800

 tctgggcaac atggccctac cagacactgc tgctgccccg tcggcatgtg 850

 cggcggctac ctgagctgac ccctgctgag cgtgatgatc tagcctccat 900

 catgaagaag ctcttgacca agtatgacaa cctctttgag acgtcctttc 950

 cctactccat gggctggcat ggggctccca caggatcaga ggctggggcc 1000

 aactggaacc attggcagct gcacgctcat tactaccctc cgctcctgcg 1050

 ctctgccact gtccggaaat tcatggttgg ctacgaaatg cttgctcagg 1100

 ctcagaggga cctcacccct gagcaggctg cagagagact aagggcactt 1150

 cctgaggttc attaccacct ggggcagaag gacagggaga cagcaaccat 1200

 cgcctgacca cgccgaccac agggccttga atcctttttt gttttcaaca 1250

 gtcttgctga attaagcaga aagggccttg aatcctggcc tggaatttgg 1300

 gcagatatag cattaataaa actgtgcatc tcaaaaaaaa aaaaaaa 1347

<210> 816
<211> 379
<212> PRT
<213> Homo sapien

<400> 816
 Met Ser Arg Ser Gly Thr Asp Pro Gln Gln Arg Gln Gln Ala Ser
   1               5                  10                  15

 Glu Ala Asp Ala Ala Ala Ala Thr Phe Arg Ala Asn Asp His Gln
                  20                  25                  30

 His Ile Arg Tyr Asn Pro Leu Gln Asp Glu Trp Val Leu Val Ser
                  35                  40                  45

 Ala His Arg Met Lys Arg Pro Trp Gln Gly Gln Val Glu Pro Gln
                  50                  55                  60

 Leu Leu Lys Thr Val Pro Arg His Asp Pro Leu Asn Pro Leu Cys
                  65                  70                  75

 Pro Gly Ala Ile Arg Ala Asn Gly Glu Val Asn Pro Gln Tyr Asp
                  80                  85                  90

 Ser Thr Phe Leu Phe Asp Asn Asp Phe Pro Ala Leu Gln Pro Asp
                  95                 100                 105

 Ala Pro Ser Pro Gly Pro Ser Asp His Pro Leu Phe Gln Ala Lys
                 110                 115                 120

 Ser Ala Arg Gly Val Cys Lys Val Met Cys Phe His Pro Trp Ser
                 125                 130                 135

 Asp Val Thr Leu Pro Leu Met Ser Val Pro Glu Ile Arg Ala Val
                 140                 145                 150

 Val Asp Ala Trp Ala Ser Val Thr Glu Glu Leu Gly Ala Gln Tyr
                 155                 160                 165

 Pro Trp Val Gln Ile Phe Glu Asn Lys Gly Ala Met Met Gly Cys
                 170                 175                 180

 Ser Asn Pro His Pro His Cys Gln Val Trp Ala Ser Ser Phe Leu
                 185                 190                 195

 Pro Asp Ile Ala Gln Arg Glu Glu Arg Ser Gln Gln Ala Tyr Lys
                 200                 205                 210

 Ser Gln His Gly Glu Pro Leu Leu Met Glu Tyr Ser Arg Gln Glu
                 215                 220                 225

 Leu Leu Arg Lys Glu Arg Leu Val Leu Thr Ser Glu His Trp Leu
                 230                 235                 240

 Val Leu Val Pro Phe Trp Ala Thr Trp Pro Tyr Gln Thr Leu Leu
                 245                 250                 255

 Leu Pro Arg Arg His Val Arg Arg Leu Pro Glu Leu Thr Pro Ala
                 260                 265                 270

 Glu Arg Asp Asp Leu Ala Ser Ile Met Lys Lys Leu Leu Thr Lys
                 275                 280                 285

 Tyr Asp Asn Leu Phe Glu Thr Ser Phe Pro Tyr Ser Met Gly Trp
                 290                 295                 300

 His Gly Ala Pro Thr Gly Ser Glu Ala Gly Ala Asn Trp Asn His
                 305                 310                 315

 Trp Gln Leu His Ala His Tyr Tyr Pro Pro Leu Leu Arg Ser Ala
                 320                 325                 330

 Thr Val Arg Lys Phe Met Val Gly Tyr Glu Met Leu Ala Gln Ala
                 335                 340                 345

 Gln Arg Asp Leu Thr Pro Glu Gln Ala Ala Glu Arg Leu Arg Ala
                 350                 355                 360

 Leu Pro Glu Val His Tyr His Leu Gly Gln Lys Asp Arg Glu Thr
                 365                 370                 375

 Ala Thr Ile Ala


<210> 817
<211> 3745
<212> DNA
<213> Homo sapien

<400> 817
 gaattcggca cgaggccatt gaatcccagt cctaacagaa gtactgcgaa 50

 tcttgtggcc tcattctgaa caaaagggat tagagaagaa aaatctcttg 100

 atataaggct tgaaagcaag ggcaggcaat cttggttgtg aatattttct 150

 gatttttcca gaaatcaagc agaagattga gctgctgatg tcagttaact 200

 ctgagaagtc gtcctcttca gaaaggccgg agcctcaaca gaaagctcct 250

 ttagttcctc ctcctccacc gccaccacca ccaccaccgc cacctttgcc 300

 agaccccaca cccccggagc cagaggagga gatcctggga tcagatgatg 350

 aggagcaaga ggaccctgcg gactactgca aaggtggata tcatccagtg 400

 aaaattggag acctcttcaa tggccggtat catgttatta gaaagcttgg 450

 atgggggcac ttctctactg tctggctgtg ctgggatatg caggggaaaa 500

 gatttgttgc aatgaaagtt gtaaaaagtg cccagcatta tacggagaca 550

 gccttggatg aaataaaatt gctcaaatgt gttcgagaaa gtgatcccag 600

 tgacccaaac aaagacatgg tggtccagct cattgacgac ttcaagattt 650

 caggcatgaa tgggatacat gtctgcatgg tcttcgaagt acttggccac 700

 catctcctca agtggatcat caaatccaac tatcaaggcc tcccagtacg 750

 ttgtgtgaag agtatcattc gacaggtcct tcaagggtta gattacttac 800

 acagtaagtg caagatcatt catactgaca taaagccgga aaatatcttg 850

 atgtgtgtgg atgatgcata tgtgagaaga atggcagctg agcctgagtg 900

 gcagaaagca ggtgctcctc ctccttcagg gtctgcagtg agtacggctc 950

 cacagcagaa acctatagga aaaatatcta aaaacaaaaa gaaaaaactg 1000

 aaaaagaaac agaagaggca ggctgagtta ttggagaagc gcctgcagga 1050

 gatagaagaa ttggagcgag aagctgaaag gaaaataata gaagaaaaca 1100

 tcacctcagc tgcaccttcc aatgaccagg atggcgaata ctgcccagag 1150

 gtgaaactaa aaacaacagg attagaggag gcggctgagg cagagactgc 1200

 aaaggacaat ggtgaagctg aggaccagga agagaaagaa gatgctgaga 1250

 aagaaaacat tgaaaaagat gaagatgatg tagatcagga acttgcgaac 1300

 atagacccta cgtggataga atcacctaaa accaatggcc atattgagaa 1350

 tggcccattc tcactggagc agcaactgga cgatgaagat gatgatgaag 1400

 aagactgccc aaatcctgag gaatataatc ttgatgagcc aaatgcagaa 1450

 agtgattaca catatagcag ctcctatgaa caattcaatg gtgaattgcc 1500

 aaatggacga cataaaattc ccgagtcaca gttcccagag ttttccacct 1550

 cgttgttctc tggatcctta gaacctgtgg cctgcggctc tgtgctttct 1600

 gagggatcac cacttactga gcaagaggag agcagtccat cccatgacag 1650

 aagcagaacg gtttcagcct ccagtactgg ggatttgcca aaagcaaaaa 1700

 cccgggcagc tgacttgttg gtgaatcccc tggatccgcg gaatcgagat 1750

 aaaattagag taaaaattgc tgacctggga aatgcttgtt gggtgcataa 1800

 acacttcacg gaagacatcc agacgcgtca gtaccgctcc atagaggttt 1850

 taataggagc ggggtacagc acccctgcgg acatctggag cacggcgtgt 1900

 atggcatttg agctggcaac gggagattat ttgtttgaac cacattctgg 1950

 ggaagactat tccagagacg aagaccacat agcccacatc atagagctgc 2000

 taggcagtat tccaaggcac tttgctctat ctggaaaata ttctcgggaa 2050

 ttcttcaatc gcagaggaga actgcgacac atcaccaagc tgaagccctg 2100

 gagcctcttt gatgtacttg tggaaaagta tggctggccc catgaagatg 2150

 ctgcacagtt tacagatttc ctgatcccga tgttagaaat ggttccagaa 2200

 aaacgagcct cagctggcga atgtcggcat ccttggttga attcttagca 2250

 aattctacca atattgcatt ctgagctagc aaatgttccc agtacattgg 2300

 acctaaacgg tgactctcat tctttaacag gattacaagt gagctggctt 2350

 catcctcaga cctttatttt gctttgaggt actgttgttt gacattttgc 2400

 tttttgtgca ctgtgatcct ggggaagggt agtcttttgt cttcagctaa 2450

 gtagtttact gaccattttc ttctggaaac aataacatgt ctctaagcat 2500

 tgtttcttgt gttgtgtgac attcaaatgt catttttttg aatgaaaaat 2550

 actttcccct ttgtgttttg gcaggttttg taactattta tgaagaaata 2600

 ttttagctga gtactatata atttacaatc ttaagaaatt atcaagttgg 2650

 aaccaagaaa tagcaaggaa atgtacaatt ttatcttctg gcaaagggac 2700

 atcattcctg tattatagtg tatgtaaatg caccctgtaa atgttacttt 2750

 ccattaaata tgggaggggg actcaaattt cagaaaagct accaagtctt 2800

 gagtgctttg tagcctatgt tgcatgtagc ggactttaac tgctccaagg 2850

 agttgtgcaa acttttcatt ccataacagt cttttcacat tggattttaa 2900

 acaaagtggc tctgggttat aagatgtcat tctctatatg gcactttaaa 2950

 ggaagaaaag atatgtttct cattctaaaa tatgcattat aatttagcag 3000

 tcccatttgt gattttgcat atttttaaaa gtacttttaa agaagagcaa 3050

 tttcccttta aaaatgtgat ggctcagtac catgtcatgt tgcctcctct 3100

 gggcgctgta agttaagctc tacatagatt aaattggaga aacgtgttaa 3150

 ttgtgtggaa tgaaaaaata catatatttt tggaaaagca tgatcatgct 3200

 tgtctagaac acaaggtatg gtatatacaa tttgcagtgc agtgggcaga 3250

 atacttctca cagctcaaag ataacagtga tcacattcat tccataggta 3300

 gctttacgtg tggctacaac aaattttact agctttttca ttgtctttcc 3350

 atgaaacgaa gttgagaaaa tgattttccc tttgcaggtt gcacacagtt 3400

 ttgtttatgc atttccttaa aattaattgt agactccagg atacaaacca 3450

 tagtaggcaa tacaatttag aatgtaatat atagaggtat attagcctct 3500

 ttagaagtca gtggattgaa tgtcttttta ttttaaattt tacattcatt 3550

 aaggtgcctc gtttttgact ttgtccatta acatttatcc atatgccttt 3600

 gcaataacta gattgtgaaa agctaacaag tgttgtaaca ataatccatt 3650

 gtttgaggtg cttgcagttg tcttaaaaat taaagtgttt tggttttttt 3700

 ttttccagaa aaaaaaaaaa aaaaaaaaaa aaaaaaaatt cctgc 3745

<210> 818
<211> 686
<212> PRT
<213> Homo sapien

<400> 818
 Met Ser Val Asn Ser Glu Lys Ser Ser Ser Ser Glu Arg Pro Glu
   1               5                  10                  15

 Pro Gln Gln Lys Ala Pro Leu Val Pro Pro Pro Pro Pro Pro Pro
                  20                  25                  30

 Pro Pro Pro Pro Pro Pro Leu Pro Asp Pro Thr Pro Pro Glu Pro
                  35                  40                  45

 Glu Glu Glu Ile Leu Gly Ser Asp Asp Glu Glu Gln Glu Asp Pro
                  50                  55                  60

 Ala Asp Tyr Cys Lys Gly Gly Tyr His Pro Val Lys Ile Gly Asp
                  65                  70                  75

 Leu Phe Asn Gly Arg Tyr His Val Ile Arg Lys Leu Gly Trp Gly
                  80                  85                  90

 His Phe Ser Thr Val Trp Leu Cys Trp Asp Met Gln Gly Lys Arg
                  95                 100                 105

 Phe Val Ala Met Lys Val Val Lys Ser Ala Gln His Tyr Thr Glu
                 110                 115                 120

 Thr Ala Leu Asp Glu Ile Lys Leu Leu Lys Cys Val Arg Glu Ser
                 125                 130                 135

 Asp Pro Ser Asp Pro Asn Lys Asp Met Val Val Gln Leu Ile Asp
                 140                 145                 150

 Asp Phe Lys Ile Ser Gly Met Asn Gly Ile His Val Cys Met Val
                 155                 160                 165

 Phe Glu Val Leu Gly His His Leu Leu Lys Trp Ile Ile Lys Ser
                 170                 175                 180

 Asn Tyr Gln Gly Leu Pro Val Arg Cys Val Lys Ser Ile Ile Arg
                 185                 190                 195

 Gln Val Leu Gln Gly Leu Asp Tyr Leu His Ser Lys Cys Lys Ile
                 200                 205                 210

 Ile His Thr Asp Ile Lys Pro Glu Asn Ile Leu Met Cys Val Asp
                 215                 220                 225

 Asp Ala Tyr Val Arg Arg Met Ala Ala Glu Pro Glu Trp Gln Lys
                 230                 235                 240

 Ala Gly Ala Pro Pro Pro Ser Gly Ser Ala Val Ser Thr Ala Pro
                 245                 250                 255

 Gln Gln Lys Pro Ile Gly Lys Ile Ser Lys Asn Lys Lys Lys Lys
                 260                 265                 270

 Leu Lys Lys Lys Gln Lys Arg Gln Ala Glu Leu Leu Glu Lys Arg
                 275                 280                 285

 Leu Gln Glu Ile Glu Glu Leu Glu Arg Glu Ala Glu Arg Lys Ile
                 290                 295                 300

 Ile Glu Glu Asn Ile Thr Ser Ala Ala Pro Ser Asn Asp Gln Asp
                 305                 310                 315

 Gly Glu Tyr Cys Pro Glu Val Lys Leu Lys Thr Thr Gly Leu Glu
                 320                 325                 330

 Glu Ala Ala Glu Ala Glu Thr Ala Lys Asp Asn Gly Glu Ala Glu
                 335                 340                 345

 Asp Gln Glu Glu Lys Glu Asp Ala Glu Lys Glu Asn Ile Glu Lys
                 350                 355                 360

 Asp Glu Asp Asp Val Asp Gln Glu Leu Ala Asn Ile Asp Pro Thr
                 365                 370                 375

 Trp Ile Glu Ser Pro Lys Thr Asn Gly His Ile Glu Asn Gly Pro
                 380                 385                 390

 Phe Ser Leu Glu Gln Gln Leu Asp Asp Glu Asp Asp Asp Glu Glu
                 395                 400                 405

 Asp Cys Pro Asn Pro Glu Glu Tyr Asn Leu Asp Glu Pro Asn Ala
                 410                 415                 420

 Glu Ser Asp Tyr Thr Tyr Ser Ser Ser Tyr Glu Gln Phe Asn Gly
                 425                 430                 435

 Glu Leu Pro Asn Gly Arg His Lys Ile Pro Glu Ser Gln Phe Pro
                 440                 445                 450

 Glu Phe Ser Thr Ser Leu Phe Ser Gly Ser Leu Glu Pro Val Ala
                 455                 460                 465

 Cys Gly Ser Val Leu Ser Glu Gly Ser Pro Leu Thr Glu Gln Glu
                 470                 475                 480

 Glu Ser Ser Pro Ser His Asp Arg Ser Arg Thr Val Ser Ala Ser
                 485                 490                 495

 Ser Thr Gly Asp Leu Pro Lys Ala Lys Thr Arg Ala Ala Asp Leu
                 500                 505                 510

 Leu Val Asn Pro Leu Asp Pro Arg Asn Arg Asp Lys Ile Arg Val
                 515                 520                 525

 Lys Ile Ala Asp Leu Gly Asn Ala Cys Trp Val His Lys His Phe
                 530                 535                 540

 Thr Glu Asp Ile Gln Thr Arg Gln Tyr Arg Ser Ile Glu Val Leu
                 545                 550                 555

 Ile Gly Ala Gly Tyr Ser Thr Pro Ala Asp Ile Trp Ser Thr Ala
                 560                 565                 570

 Cys Met Ala Phe Glu Leu Ala Thr Gly Asp Tyr Leu Phe Glu Pro
                 575                 580                 585

 His Ser Gly Glu Asp Tyr Ser Arg Asp Glu Asp His Ile Ala His
                 590                 595                 600

 Ile Ile Glu Leu Leu Gly Ser Ile Pro Arg His Phe Ala Leu Ser
                 605                 610                 615

 Gly Lys Tyr Ser Arg Glu Phe Phe Asn Arg Arg Gly Glu Leu Arg
                 620                 625                 630

 His Ile Thr Lys Leu Lys Pro Trp Ser Leu Phe Asp Val Leu Val
                 635                 640                 645

 Glu Lys Tyr Gly Trp Pro His Glu Asp Ala Ala Gln Phe Thr Asp
                 650                 655                 660

 Phe Leu Ile Pro Met Leu Glu Met Val Pro Glu Lys Arg Ala Ser
                 665                 670                 675

 Ala Gly Glu Cys Arg His Pro Trp Leu Asn Ser
                 680                 685

<210> 819
<211> 507
<212> DNA
<213> Homo sapien

<400> 819
 ggtgcttctg agatgtgggc ttgcacacgc tgttgctata gtacgtgtga 50

 tcctgactgc tgtcatggcg tgccctctgg agaaggccct ggatgtgatg 100

 gtgtccacct tccacaagta ctcgggcaaa gagggtgaca agttcaagct 150

 caacaagtca gaactaaagg agctgctgac ccgggagctg cccagcttct 200

 tggggaaaag gacagatgaa gctgctttcc agaagctgat gagcaacttg 250

 gacagcaaca gggacaacga ggtggacttc caagagtact gtgtcttcct 300

 gtcctgcatc gccatgatgt gtaacgaatt ctttgaaggc ttcccagata 350

 agcagcccag gaagaaatga aaactcctct gatgtggttg gggggtctgc 400

 cagctggggc cctccctgtc gccagtgggc actttttttt ttccaccctg 450

 gctccttcag acacgtgctt gatgctgagc aagttcaata aagattcttg 500

 gaagttt 507

<210> 820
<211> 101
<212> PRT
<213> Homo sapien

<400> 820
 Met Ala Cys Pro Leu Glu Lys Ala Leu Asp Val Met Val Ser Thr
   1               5                  10                  15

 Phe His Lys Tyr Ser Gly Lys Glu Gly Asp Lys Phe Lys Leu Asn
                  20                  25                  30

 Lys Ser Glu Leu Lys Glu Leu Leu Thr Arg Glu Leu Pro Ser Phe
                  35                  40                  45

 Leu Gly Lys Arg Thr Asp Glu Ala Ala Phe Gln Lys Leu Met Ser
                  50                  55                  60

 Asn Leu Asp Ser Asn Arg Asp Asn Glu Val Asp Phe Gln Glu Tyr
                  65                  70                  75

 Cys Val Phe Leu Ser Cys Ile Ala Met Met Cys Asn Glu Phe Phe
                  80                  85                  90

 Glu Gly Phe Pro Asp Lys Gln Pro Arg Lys Lys
                  95                 100

<210> 821
<211> 6519
<212> DNA
<213> Homo sapien

<400> 821
 gcacgagcgg ctccggcggc gccatgacgc gctgggtgcc caccaagcgc 50

 gaggagaagt acggcgtggc tttttataac tatgatgcca gaggagcgga 100

 tgaactttct ttacagatcg gagacactgt gcacatctta gaaacatatg 150

 aagggtggta ccgaggttac acgttacgaa aaaagtctaa gaagggtata 200

 tttcctgctt catatattca tcttaaagaa gcgatagttg aaggaaaagg 250

 gcaacatgaa acagtcatcc cgggtgacct ccccctcatc caggaagtca 300

 ccacgacact ccgagagtgg tccaccatct ggaggcagct ctacgtgcaa 350

 gataacaggg agatgtttcg aagtgtgcgg cacatgatct atgaccttat 400

 tgaatggcga tcacaaattc tttctggaac tctgcctcag gatgaactca 450

 aagaactgaa gaagaaggtc acagccaaaa ttgattatgg aaacagaatt 500

 ctagatttgg acctggtggt tagagatgaa gatgggaata ttttggatcc 550

 agaattaact agcacgatta gtctcttcag agctcatgaa atagcttcta 600

 aacaagtgga ggaaaggtta caagaggaaa aatctcaaaa gcagaacata 650

 gatattaaca gacaagccaa gtttgctgca accccttctc tggccttgtt 700

 tgtgaacctc aaaaatgtgg tttgtaaaat aggagaagat gctgaagtcc 750

 tcatgtctct atatgaccct gtggagtcca aattcatcag tgagaactac 800

 ctggttcgct ggtccagttc aggattacct aaagacatag acagattaca 850

 taatttgcga gccgtgttta ctgacctcgg aagcaaagac ctgaaaaggg 900

 agaaaatcag ttttgtctgt cagattgttc gcgtgggtcg catggagctg 950

 agggacaaca acaccaggaa actgacctcg gggttgcggc gaccttttgg 1000

 agtggctgtg atggatgtaa cagatataat aaatggaaaa gtagatgatg 1050

 aagataagca gcatttcatt ccctttcagc cggtggcagg ggagaatgac 1100

 ttccttcaga ctgttataaa caaagtcatc gctgccaaag aagtcaacca 1150

 caaggggcag ggtttgtggg taacattgaa attacttcct ggagatatcc 1200

 atcagatccg aaaagagttt ccgcatttag tggacaggac cacagctgtg 1250

 gctcgaaaaa cagggtttcc ggagataatc atgcctggtg atgttcgaaa 1300

 tgatatctat gtaacattag ttcaaggaga ttttgataaa ggaagcaaaa 1350

 caacagcgaa gaacgtggag gtcacggtgt ctgtgtacga tgaggatggg 1400

 aaacgattag agcatgtgat tttcccgggt gctggtgatg aagcgatttc 1450

 agagtacaaa tctgtgattt actaccaagt aaagcagcca cgctggtttg 1500

 agactgttaa ggtggccatt cccatcgagg acgttaaccg cagtcacctt 1550

 cggtttacct tccgccacag gtcatcacag gactctaagg ataaatctga 1600

 gaaaatattt gcactagcat ttgtcaagct gatgagatac gatggtacca 1650

 ccctgcgaga cggagagcac gatcttatcg tctataaggc cgaagcgaag 1700

 aagctggaag atgctgccac gtacttgagt ctgccctcca cgaaggcaga 1750

 gttggaagaa aagggccact cggccaccgg caagagcatg cagagccttg 1800

 ggagctgcac cattagcaag gactccttcc agatctccac gctcgtgtgc 1850

 tccaccaaac tgactcagaa cgtggacctt ctggggctct tgaaatggcg 1900

 ctccaacacc agcctgctgc agcagaactt gaggcagctg atgaaagtcg 1950

 atggtggtga agtagtgaag tttcttcagg acacgttgga tgccctcttc 2000

 aacatcatga tggagaactc agagagtgag acttttgaca cgttagtctt 2050

 tgatgctctg gtatttatca ttggactgat tgctgataga aaatttcagc 2100

 attttaatcc tgttttggaa acttacatta agaaacactt tagtgcaacg 2150

 ttagcctaca cgaagttgac aaaagtgttg aagaactacg tggacggtgc 2200

 tgagaagccg ggagtaaatg agcagctgta caaagccatg aaagcgctag 2250

 aatccatctt caagttcatc gtgcgctcca ggatcctgtt caatcaactg 2300

 tatgaaaaca agggagaggc tgacttcgtg gaatctttgc tgcagctctt 2350

 caggtccatc aatgacatga tgagcagcat gtcagaccag accgtccggg 2400

 tgaagggggc agcactgaaa tacttaccaa cgatcgtcaa cgatgtgaaa 2450

 ttggtgtttg atcccaaaga gctcagcaaa atgtttactg aattcatcct 2500

 caatgttccc atgggcttgc tgaccatcca gaaactctac tgcttgatcg 2550

 aaatcgtcca cagtgacctc ttcacacagc atgactgcag agagatcctg 2600

 cttcccatga tgaccgatca gctcaagtac catctggaga gacaggagga 2650

 cctggaggcc tgctgtcagc tgctcagcca catcctggag gtgctgtaca 2700

 ggaaggacgt ggggccaacc cagaggcacg tccagattat catggagaaa 2750

 cttctccgga ccgtgaaccg aaccgtcatt tccatgggac gagattctga 2800

 actcattgga aacttcgtgg cttgcatgac agctatttta cgacaaatgg 2850

 aagattacca ttatgcccac ttgatcaaga cttttgggaa aatgaggact 2900

 gatgtggtag atttcctaat ggaaacattc atcatgttta agaacctcat 2950

 tggaaagaac gtttacccct tcgactgggt gatcatgaac atggtgcaaa 3000

 ataaagtctt cctgcgagca attaatcagt atgcagatat gctgaacaaa 3050

 aaatttctgg atcaagccaa ctttgagcta cagctgtgga acaactactt 3100

 tcacctggct gttgctttcc ttactcaaga gtccctgcaa ctggagaatt 3150

 tttcaagtgc caagagagcc aaaatcctta acaagtacgg agatatgagg 3200

 agacagattg gctttgaaat cagagacatg tggtacaacc ttggtcaaca 3250

 caagataaag ttcattccag aaatggtggg cccaatatta gaaatgacat 3300

 taattcccga gacggagctg cgcaaagcca ccatccccat cttctttgat 3350

 atgatgcagt gtgaattcca ttcgacccga agcttccaaa tgtttgaaaa 3400

 tgagatcatc accaagctgg atcatgaagt cgaaggaggc agaggagacg 3450

 aacagtacaa agtgttattt gataaaatcc ttctggaaca ctgcaggaag 3500

 cacaaatacc tcgccaaaac aggagaaact tttgtaaaac tcgttgtgcg 3550

 cttaatggaa aggcttttgg attatagaac catcatgcac gacgagaaca 3600

 aagaaaaccg catgagctgc accgtcaatg tgctgaattt ctacaaagaa 3650

 attgaaagag aagaaatgta tataaggtat ttgtacaagc tctgtgacct 3700

 gcacaaggag tgtgataact acaccgaagc ggcttacacc ttgcttctcc 3750

 atgcaaagct tcttaagtgg tcggaggatg tgtgtgtggc ccacctcacc 3800

 cagcgggacg ggtaccaggc caccacgcag ggacagctga aggagcagct 3850

 ctaccaggaa atcatccact acttcgacaa aggcaagatg tgggaggagg 3900

 ccattgcctt gggcaaggag ctagccgagc agtatgagaa cgaaatgttt 3950

 gattatgagc aactcagcga attgctgaaa aaacaggctc agttttatga 4000

 aaacatcgtc aaagtgatca ggcccaagcc tgactatttt gctgttggct 4050

 actacggaca agggttcccc acattcctgc ggggaaaagt tttcatttac 4100

 cgagggaaag agtatgagcg ccgggaagat tttgaggctc ggctcttaac 4150

 tcagtttcca aacgccgaga aaatgaagac aacatctcca ccaggcgacg 4200

 atattaaaaa ctctcctggc cagtatattc agtgcttcac agtgaagccc 4250

 aaactcgatc tgcctcctaa gtttcacagg ccagtgtcag agcagattgt 4300

 aagtttttac agggtgaacg aggtccagcg atttgaatat tctcggccaa 4350

 tccggaaggg agagaaaaac ccagacaatg aatttgcgaa tatgtggatc 4400

 gagagaacca tatatacaac tgcatataaa ttacctggaa ttttaaggtg 4450

 gtttgaggtc aagtctgttt tcatggtgga aatcagcccc ctggagaatg 4500

 ccatcgagac catgcagctg acgaacgaca agatcaacag catggtgcag 4550

 cagcacctgg atgaccccag cctgcccatc aacccgctct ccatgctcct 4600

 gaacggcatc gtggacccag ctgtcatggg gggcttcgca aactacgaaa 4650

 aggccttctt tacagaccgg tacctgcagg agcaccctga ggcccatgaa 4700

 aagatcgaga agctcaagga cctgattgct tggcagattc cttttctggc 4750

 cgaagggatc agaatccatg gagacaaagt cacggaggca ctgaggccgt 4800

 tccacgagag gatggaggcc tgtttcaaac agctgaagga aaaggtggag 4850

 aaagagtacg gcgtccgaat catgccctca agtctggatg atagaagagg 4900

 cagccgcccc cggtccatgg tgcggtcctt cacgatgcct tcctcatccc 4950

 gccctctgtc tgtggcctct gtctcttccc tctcatcgga cagcaccccc 5000

 tccagaccag gctccgacgg gtttgccctg gagcctctcc tgccaaagaa 5050

 aatgcactcc aggtcccagg acaagctgga caaggatgac ctggagaagg 5100

 agaagaagga caagaagaag gaaaaaagga acagcaaaca tcaagagata 5150

 tttgagaaag aatttaaacc caccgacatt tccctgcagc agtctgaggc 5200

 tgtgatcctt tcggaaacga taagtcccct gcggccccag agaccgaaga 5250

 gccaggtgat gaacgtcatt ggaagcgaaa ggcgcttctc ggtgtccccc 5300

 tcgtcaccgt cctcccagca aacaccccct ccagttacac caagagccaa 5350

 gctcagcttc agcatgcagt cgagcttgga gctgaacggc atgacggggg 5400

 cggacgtggc cgatgtccca ccccctctgc ctctcaaagg cagcgtggca 5450

 gattacggga atttgatgga aaaccaggac ttgctgggct cgccaacacc 5500

 tccacctccc cctccacacc agaggcatct gccacctcca ctgcccagca 5550

 aaactccgcc tcctccccct ccaaagacaa ctcgcaagca gacatcggtg 5600

 gactctggga tcgtgcagtg acatcgcaag gctctctgga aagagtgtgc 5650

 tgcccctccc catctccatg ccctctcctt ctgtgtcccc tgagtctgct 5700

 gtttacctca ttgggcctgt gatgttaaca tttcgtgcga ctgctttttc 5750

 ttcaaaggag ttcagttctc accatggagt gagtggcctt tagcgtcatg 5800

 gagcaaggtg ggtctgggag gtagatatgg gtccgggatg tgccatcgta 5850

 gttaccagag ttgggggcct ctgagtgtgt ctggctctga gagagtctga 5900

 gtcttgccca aacattcttt ctttttgtgc caaatgactt gcatttgcaa 5950

 agagctcaat tgctctgagc tcagccaagt aggagaggct aggccatcac 6000

 tcttgggaag ctgtgtagtg atgatgtata agaatcctcc tcactgtcat 6050

 gggatgttgt atccagcccc tccttgttcc agccggtggt gtgacttcgt 6100

 tggttgaggt gtgtctccaa cctacatcag accatgaagt tcaacccctc 6150

 cagggaagct cctgatttcc cctgcataat tgaaaatagg atattctcag 6200

 ctattgaaca gttactaatt tatggggtgg aaacagcatt aagaatactg 6250

 aatcaaatgg aaaaacaaat gaatacagga agataagtgt tcgttctttt 6300

 ctgaaaaaag agtatgtgta ccacaagagc tggttttaat tgggtgaatt 6350

 gtttttgtcc tcattctgta cagaaatttg tatatatgat ggttcttaga 6400

 acttgtttta atttttgtgg tccttctgtt tattataata ggcgtccacc 6450

 aatgattatc catatgtgtt cttaattttt aactgctgga agtgttaaaa 6500

 cacacacacc ccggaattc 6519

<210> 822
<211> 1865
<212> PRT
<213> Homo sapien

<400> 822
 Met Thr Arg Trp Val Pro Thr Lys Arg Glu Glu Lys Tyr Gly Val
   1               5                  10                  15

 Ala Phe Tyr Asn Tyr Asp Ala Arg Gly Ala Asp Glu Leu Ser Leu
                  20                  25                  30

 Gln Ile Gly Asp Thr Val His Ile Leu Glu Thr Tyr Glu Gly Trp
                  35                  40                  45

 Tyr Arg Gly Tyr Thr Leu Arg Lys Lys Ser Lys Lys Gly Ile Phe
                  50                  55                  60

 Pro Ala Ser Tyr Ile His Leu Lys Glu Ala Ile Val Glu Gly Lys
                  65                  70                  75

 Gly Gln His Glu Thr Val Ile Pro Gly Asp Leu Pro Leu Ile Gln
                  80                  85                  90

 Glu Val Thr Thr Thr Leu Arg Glu Trp Ser Thr Ile Trp Arg Gln
                  95                 100                 105

 Leu Tyr Val Gln Asp Asn Arg Glu Met Phe Arg Ser Val Arg His
                 110                 115                 120

 Met Ile Tyr Asp Leu Ile Glu Trp Arg Ser Gln Ile Leu Ser Gly
                 125                 130                 135

 Thr Leu Pro Gln Asp Glu Leu Lys Glu Leu Lys Lys Lys Val Thr
                 140                 145                 150

 Ala Lys Ile Asp Tyr Gly Asn Arg Ile Leu Asp Leu Asp Leu Val
                 155                 160                 165

 Val Arg Asp Glu Asp Gly Asn Ile Leu Asp Pro Glu Leu Thr Ser
                 170                 175                 180

 Thr Ile Ser Leu Phe Arg Ala His Glu Ile Ala Ser Lys Gln Val
                 185                 190                 195

 Glu Glu Arg Leu Gln Glu Glu Lys Ser Gln Lys Gln Asn Ile Asp
                 200                 205                 210

 Ile Asn Arg Gln Ala Lys Phe Ala Ala Thr Pro Ser Leu Ala Leu
                 215                 220                 225

 Phe Val Asn Leu Lys Asn Val Val Cys Lys Ile Gly Glu Asp Ala
                 230                 235                 240

 Glu Val Leu Met Ser Leu Tyr Asp Pro Val Glu Ser Lys Phe Ile
                 245                 250                 255

 Ser Glu Asn Tyr Leu Val Arg Trp Ser Ser Ser Gly Leu Pro Lys
                 260                 265                 270

 Asp Ile Asp Arg Leu His Asn Leu Arg Ala Val Phe Thr Asp Leu
                 275                 280                 285

 Gly Ser Lys Asp Leu Lys Arg Glu Lys Ile Ser Phe Val Cys Gln
                 290                 295                 300

 Ile Val Arg Val Gly Arg Met Glu Leu Arg Asp Asn Asn Thr Arg
                 305                 310                 315

 Lys Leu Thr Ser Gly Leu Arg Arg Pro Phe Gly Val Ala Val Met
                 320                 325                 330

 Asp Val Thr Asp Ile Ile Asn Gly Lys Val Asp Asp Glu Asp Lys
                 335                 340                 345

 Gln His Phe Ile Pro Phe Gln Pro Val Ala Gly Glu Asn Asp Phe
                 350                 355                 360

 Leu Gln Thr Val Ile Asn Lys Val Ile Ala Ala Lys Glu Val Asn
                 365                 370                 375

 His Lys Gly Gln Gly Leu Trp Val Thr Leu Lys Leu Leu Pro Gly
                 380                 385                 390

 Asp Ile His Gln Ile Arg Lys Glu Phe Pro His Leu Val Asp Arg
                 395                 400                 405

 Thr Thr Ala Val Ala Arg Lys Thr Gly Phe Pro Glu Ile Ile Met
                 410                 415                 420

 Pro Gly Asp Val Arg Asn Asp Ile Tyr Val Thr Leu Val Gln Gly
                 425                 430                 435

 Asp Phe Asp Lys Gly Ser Lys Thr Thr Ala Lys Asn Val Glu Val
                 440                 445                 450

 Thr Val Ser Val Tyr Asp Glu Asp Gly Lys Arg Leu Glu His Val
                 455                 460                 465

 Ile Phe Pro Gly Ala Gly Asp Glu Ala Ile Ser Glu Tyr Lys Ser
                 470                 475                 480

 Val Ile Tyr Tyr Gln Val Lys Gln Pro Arg Trp Phe Glu Thr Val
                 485                 490                 495

 Lys Val Ala Ile Pro Ile Glu Asp Val Asn Arg Ser His Leu Arg
                 500                 505                 510

 Phe Thr Phe Arg His Arg Ser Ser Gln Asp Ser Lys Asp Lys Ser
                 515                 520                 525

 Glu Lys Ile Phe Ala Leu Ala Phe Val Lys Leu Met Arg Tyr Asp
                 530                 535                 540

 Gly Thr Thr Leu Arg Asp Gly Glu His Asp Leu Ile Val Tyr Lys
                 545                 550                 555

 Ala Glu Ala Lys Lys Leu Glu Asp Ala Ala Thr Tyr Leu Ser Leu
                 560                 565                 570

 Pro Ser Thr Lys Ala Glu Leu Glu Glu Lys Gly His Ser Ala Thr
                 575                 580                 585

 Gly Lys Ser Met Gln Ser Leu Gly Ser Cys Thr Ile Ser Lys Asp
                 590                 595                 600

 Ser Phe Gln Ile Ser Thr Leu Val Cys Ser Thr Lys Leu Thr Gln
                 605                 610                 615

 Asn Val Asp Leu Leu Gly Leu Leu Lys Trp Arg Ser Asn Thr Ser
                 620                 625                 630

 Leu Leu Gln Gln Asn Leu Arg Gln Leu Met Lys Val Asp Gly Gly
                 635                 640                 645

 Glu Val Val Lys Phe Leu Gln Asp Thr Leu Asp Ala Leu Phe Asn
                 650                 655                 660

 Ile Met Met Glu Asn Ser Glu Ser Glu Thr Phe Asp Thr Leu Val
                 665                 670                 675

 Phe Asp Ala Leu Val Phe Ile Ile Gly Leu Ile Ala Asp Arg Lys
                 680                 685                 690

 Phe Gln His Phe Asn Pro Val Leu Glu Thr Tyr Ile Lys Lys His
                 695                 700                 705

 Phe Ser Ala Thr Leu Ala Tyr Thr Lys Leu Thr Lys Val Leu Lys
                 710                 715                 720

 Asn Tyr Val Asp Gly Ala Glu Lys Pro Gly Val Asn Glu Gln Leu
                 725                 730                 735

 Tyr Lys Ala Met Lys Ala Leu Glu Ser Ile Phe Lys Phe Ile Val
                 740                 745                 750

 Arg Ser Arg Ile Leu Phe Asn Gln Leu Tyr Glu Asn Lys Gly Glu
                 755                 760                 765

 Ala Asp Phe Val Glu Ser Leu Leu Gln Leu Phe Arg Ser Ile Asn
                 770                 775                 780

 Asp Met Met Ser Ser Met Ser Asp Gln Thr Val Arg Val Lys Gly
                 785                 790                 795

 Ala Ala Leu Lys Tyr Leu Pro Thr Ile Val Asn Asp Val Lys Leu
                 800                 805                 810

 Val Phe Asp Pro Lys Glu Leu Ser Lys Met Phe Thr Glu Phe Ile
                 815                 820                 825

 Leu Asn Val Pro Met Gly Leu Leu Thr Ile Gln Lys Leu Tyr Cys
                 830                 835                 840

 Leu Ile Glu Ile Val His Ser Asp Leu Phe Thr Gln His Asp Cys
                 845                 850                 855

 Arg Glu Ile Leu Leu Pro Met Met Thr Asp Gln Leu Lys Tyr His
                 860                 865                 870

 Leu Glu Arg Gln Glu Asp Leu Glu Ala Cys Cys Gln Leu Leu Ser
                 875                 880                 885

 His Ile Leu Glu Val Leu Tyr Arg Lys Asp Val Gly Pro Thr Gln
                 890                 895                 900

 Arg His Val Gln Ile Ile Met Glu Lys Leu Leu Arg Thr Val Asn
                 905                 910                 915

 Arg Thr Val Ile Ser Met Gly Arg Asp Ser Glu Leu Ile Gly Asn
                 920                 925                 930

 Phe Val Ala Cys Met Thr Ala Ile Leu Arg Gln Met Glu Asp Tyr
                 935                 940                 945

 His Tyr Ala His Leu Ile Lys Thr Phe Gly Lys Met Arg Thr Asp
                 950                 955                 960

 Val Val Asp Phe Leu Met Glu Thr Phe Ile Met Phe Lys Asn Leu
                 965                 970                 975

 Ile Gly Lys Asn Val Tyr Pro Phe Asp Trp Val Ile Met Asn Met
                 980                 985                 990

 Val Gln Asn Lys Val Phe Leu Arg Ala Ile Asn Gln Tyr Ala Asp
                 995                1000                1005

 Met Leu Asn Lys Lys Phe Leu Asp Gln Ala Asn Phe Glu Leu Gln
                1010                1015                1020

 Leu Trp Asn Asn Tyr Phe His Leu Ala Val Ala Phe Leu Thr Gln
                1025                1030                1035

 Glu Ser Leu Gln Leu Glu Asn Phe Ser Ser Ala Lys Arg Ala Lys
                1040                1045                1050

 Ile Leu Asn Lys Tyr Gly Asp Met Arg Arg Gln Ile Gly Phe Glu
                1055                1060                1065

 Ile Arg Asp Met Trp Tyr Asn Leu Gly Gln His Lys Ile Lys Phe
                1070                1075                1080

 Ile Pro Glu Met Val Gly Pro Ile Leu Glu Met Thr Leu Ile Pro
                1085                1090                1095

 Glu Thr Glu Leu Arg Lys Ala Thr Ile Pro Ile Phe Phe Asp Met
                1100                1105                1110

 Met Gln Cys Glu Phe His Ser Thr Arg Ser Phe Gln Met Phe Glu
                1115                1120                1125

 Asn Glu Ile Ile Thr Lys Leu Asp His Glu Val Glu Gly Gly Arg
                1130                1135                1140

 Gly Asp Glu Gln Tyr Lys Val Leu Phe Asp Lys Ile Leu Leu Glu
                1145                1150                1155

 His Cys Arg Lys His Lys Tyr Leu Ala Lys Thr Gly Glu Thr Phe
                1160                1165                1170

 Val Lys Leu Val Val Arg Leu Met Glu Arg Leu Leu Asp Tyr Arg
                1175                1180                1185

 Thr Ile Met His Asp Glu Asn Lys Glu Asn Arg Met Ser Cys Thr
                1190                1195                1200

 Val Asn Val Leu Asn Phe Tyr Lys Glu Ile Glu Arg Glu Glu Met
                1205                1210                1215

 Tyr Ile Arg Tyr Leu Tyr Lys Leu Cys Asp Leu His Lys Glu Cys
                1220                1225                1230

 Asp Asn Tyr Thr Glu Ala Ala Tyr Thr Leu Leu Leu His Ala Lys
                1235                1240                1245

 Leu Leu Lys Trp Ser Glu Asp Val Cys Val Ala His Leu Thr Gln
                1250                1255                1260

 Arg Asp Gly Tyr Gln Ala Thr Thr Gln Gly Gln Leu Lys Glu Gln
                1265                1270                1275

 Leu Tyr Gln Glu Ile Ile His Tyr Phe Asp Lys Gly Lys Met Trp
                1280                1285                1290

 Glu Glu Ala Ile Ala Leu Gly Lys Glu Leu Ala Glu Gln Tyr Glu
                1295                1300                1305

 Asn Glu Met Phe Asp Tyr Glu Gln Leu Ser Glu Leu Leu Lys Lys
                1310                1315                1320

 Gln Ala Gln Phe Tyr Glu Asn Ile Val Lys Val Ile Arg Pro Lys
                1325                1330                1335

 Pro Asp Tyr Phe Ala Val Gly Tyr Tyr Gly Gln Gly Phe Pro Thr
                1340                1345                1350

 Phe Leu Arg Gly Lys Val Phe Ile Tyr Arg Gly Lys Glu Tyr Glu
                1355                1360                1365

 Arg Arg Glu Asp Phe Glu Ala Arg Leu Leu Thr Gln Phe Pro Asn
                1370                1375                1380

 Ala Glu Lys Met Lys Thr Thr Ser Pro Pro Gly Asp Asp Ile Lys
                1385                1390                1395

 Asn Ser Pro Gly Gln Tyr Ile Gln Cys Phe Thr Val Lys Pro Lys
                1400                1405                1410

 Leu Asp Leu Pro Pro Lys Phe His Arg Pro Val Ser Glu Gln Ile
                1415                1420                1425

 Val Ser Phe Tyr Arg Val Asn Glu Val Gln Arg Phe Glu Tyr Ser
                1430                1435                1440

 Arg Pro Ile Arg Lys Gly Glu Lys Asn Pro Asp Asn Glu Phe Ala
                1445                1450                1455

 Asn Met Trp Ile Glu Arg Thr Ile Tyr Thr Thr Ala Tyr Lys Leu
                1460                1465                1470

 Pro Gly Ile Leu Arg Trp Phe Glu Val Lys Ser Val Phe Met Val
                1475                1480                1485

 Glu Ile Ser Pro Leu Glu Asn Ala Ile Glu Thr Met Gln Leu Thr
                1490                1495                1500

 Asn Asp Lys Ile Asn Ser Met Val Gln Gln His Leu Asp Asp Pro
                1505                1510                1515

 Ser Leu Pro Ile Asn Pro Leu Ser Met Leu Leu Asn Gly Ile Val
                1520                1525                1530

 Asp Pro Ala Val Met Gly Gly Phe Ala Asn Tyr Glu Lys Ala Phe
                1535                1540                1545

 Phe Thr Asp Arg Tyr Leu Gln Glu His Pro Glu Ala His Glu Lys
                1550                1555                1560

 Ile Glu Lys Leu Lys Asp Leu Ile Ala Trp Gln Ile Pro Phe Leu
                1565                1570                1575

 Ala Glu Gly Ile Arg Ile His Gly Asp Lys Val Thr Glu Ala Leu
                1580                1585                1590

 Arg Pro Phe His Glu Arg Met Glu Ala Cys Phe Lys Gln Leu Lys
                1595                1600                1605

 Glu Lys Val Glu Lys Glu Tyr Gly Val Arg Ile Met Pro Ser Ser
                1610                1615                1620

 Leu Asp Asp Arg Arg Gly Ser Arg Pro Arg Ser Met Val Arg Ser
                1625                1630                1635

 Phe Thr Met Pro Ser Ser Ser Arg Pro Leu Ser Val Ala Ser Val
                1640                1645                1650

 Ser Ser Leu Ser Ser Asp Ser Thr Pro Ser Arg Pro Gly Ser Asp
                1655                1660                1665

 Gly Phe Ala Leu Glu Pro Leu Leu Pro Lys Lys Met His Ser Arg
                1670                1675                1680

 Ser Gln Asp Lys Leu Asp Lys Asp Asp Leu Glu Lys Glu Lys Lys
                1685                1690                1695

 Asp Lys Lys Lys Glu Lys Arg Asn Ser Lys His Gln Glu Ile Phe
                1700                1705                1710

 Glu Lys Glu Phe Lys Pro Thr Asp Ile Ser Leu Gln Gln Ser Glu
                1715                1720                1725

 Ala Val Ile Leu Ser Glu Thr Ile Ser Pro Leu Arg Pro Gln Arg
                1730                1735                1740

 Pro Lys Ser Gln Val Met Asn Val Ile Gly Ser Glu Arg Arg Phe
                1745                1750                1755

 Ser Val Ser Pro Ser Ser Pro Ser Ser Gln Gln Thr Pro Pro Pro
                1760                1765                1770

 Val Thr Pro Arg Ala Lys Leu Ser Phe Ser Met Gln Ser Ser Leu
                1775                1780                1785

 Glu Leu Asn Gly Met Thr Gly Ala Asp Val Ala Asp Val Pro Pro
                1790                1795                1800

 Pro Leu Pro Leu Lys Gly Ser Val Ala Asp Tyr Gly Asn Leu Met
                1805                1810                1815

 Glu Asn Gln Asp Leu Leu Gly Ser Pro Thr Pro Pro Pro Pro Pro
                1820                1825                1830

 Pro His Gln Arg His Leu Pro Pro Pro Leu Pro Ser Lys Thr Pro
                1835                1840                1845

 Pro Pro Pro Pro Pro Lys Thr Thr Arg Lys Gln Thr Ser Val Asp
                1850                1855                1860

 Ser Gly Ile Val Gln
                1865

<210> 823
<211> 6703
<212> DNA
<213> Homo sapien

<400> 823
 cggtggcagg ggtggtagcg gcggcggcga cggtttcgtg ggggccgcgc 50

 gctgctctgt gagcggcggg tggcagcagg ggactcctga cacttcccct 100

 tccccaccga accgcgcttt ctgaaacaaa gactcatttt gaagatgttt 150

 aacaaatcat ttggaacacc ctttgggggt ggcacaggtg gctttggcac 200

 aacttcaaca tttggacaga atactggctt tggcactact agtggagggg 250

 catttggaac atctgcattt ggttctagca acaatactgg aggcctcttt 300

 ggaaattcac agactaaacc aggaggattg tttggaacca gttcatttag 350

 ccagccagct acctccacaa gcactggctt tgggtttggt acgtcaacag 400

 gaacagcaaa taccttgttt ggaactgcaa gcacagggac cagtctcttc 450

 tcatcccaaa acaatgcctt tgcacaaaat aaaccaactg gctttggcaa 500

 ttttggaacc agtactagca gtggaggact ctttggaacc acaaatacca 550

 cctctaatcc ttttggcagc acatctggct ccctctttgg gccaagtagt 600

 tttacagctg ctcctactgg gactactatt aaatttaacc ctccaactgg 650

 tacagatact atggtcaaag ctggagttag cactaacata agtaccaagc 700

 accagtgtat tactgctatg aaagaatatg aaagcaagtc actagaggaa 750

 cttcgtttag aggattatca ggctaacagg aagggcccac agaaccaggt 800

 gggagcaggt accacaactg gcttgtttgg gtcttctcca gccacttcca 850

 gcgcaacagg actcttcagc tcctccacca ctaattcagg ctttgcatat 900

 ggtcagaaca aaactgcctt tggaactagt acaactggat ttggaacaaa 950

 tccaggtggt ctctttggcc aacagaatca gcagactacc agcctcttca 1000

 gcaaaccatt tggccaggct acaaccaccc agaacactgg cttttccttt 1050

 ggtaatacca gcaccatagg acagccaagc accaacacca tgggattatt 1100

 tggagtaacc caagcctcac agcctggagg tctttttggg acagctacaa 1150

 acaccagcac tgggacagca tttggaacag gaacaggtct ctttgggcag 1200

 accaatactg gatttggtgc tgttggttcg accctgtttg gcaataacaa 1250

 gcttactaca tttggaagca gcacaaccag tgcaccttca tttggtacaa 1300

 ccagtggcgg gctctttggt tttggcacaa ataccagtgg gaatagtatt 1350

 tttggaagta aaccagcacc tgggactctt ggaactgggc ttggtgcagg 1400

 atttggaaca gctcttggtg ctggacaggc atctttgttt gggaacaacc 1450

 aacctaagat tggagggcct cttggtacag gagcctttgg ggcccctgga 1500

 tttaatacta cgacagccac tttgggcttt ggagcccccc aggccccagt 1550

 agctttgaca gatccaaatg cttctgctgc ccagcaggct gttctccagc 1600

 agcacatcaa tagtctaaca tactcacctt ttggagactc tcctctcttc 1650

 cggaatccga tgtcagaccc taagaagaag gaagagagat tgaaaccaac 1700

 aaatccagca gcccagaagg ctcttactac acctactcat tataaactga 1750

 caccccgccc tgccactaga gtccggccaa aggctttaca aacaacaggc 1800

 acagccaagt cacatctctt tgatgggctg gatgacgatg aaccatccct 1850

 agccaatgga gcattcatgc ccaagaagag cattaagaag ttggttttga 1900

 agaaccttaa taatagcaat ctcttttctc ctgttaatcg tgattcagaa 1950

 aatctagctt caccatctga atatccagaa aatggagaga gatttagttt 2000

 cctaagcaaa cctgttgatg agaatcacca gcaggatgga gatgaagatt 2050

 cccttgtttc acatttttat actaacccta ttgccaaacc tattcctcaa 2100

 accccagaaa gtgctggaaa taaacacagc aacagcaaca gtgtggatga 2150

 taccattgtt gcattaaaca tgcgtgctgc tttgcgaaat gggctggaag 2200

 gaagcagtga agaaacgtct tttcatgatg agtcacttca ggatgaccga 2250

 gaagaaatag aaaataattc ttaccatatg cacccagcag gtattattct 2300

 cactaaggtt ggttactata ctattccatc tatggatgac cttgctaaaa 2350

 ttaccaatga aaaaggagag tgcattgtct ctgatttcac tattggtcgg 2400

 aaaggttatg gttcaatcta ttttgaagga gatgtgaatt tgacaaatct 2450

 aaatttggat gatattgtgc atatccggag gaaagaagta gttgtctact 2500

 tagatgataa ccaaaaacca cctgtgggtg aagggctaaa taggaaggct 2550

 gaagttacat tggatggagt ttggccaaca gataaaacat ctcgttgttt 2600

 aataaagagc ccagatcgcc ttgctgatat caactatgaa ggaagattgg 2650

 aagcagtttc aaggaaacag ggagctcaat tcaaagaata ccggcctgaa 2700

 actggttctt gggtgtttaa ggtctcccat ttttctaagt atggccttca 2750

 ggattctgat gaagaggagg aggagcatcc gtctaaaact agtacaaaga 2800

 agttgaagac tgctcctttg cctcctgcaa gccagactac gcccttgcag 2850

 atggctctta atggcaaacc tgcacctcca cctcagagcc agagcccaga 2900

 ggtggagcag ttagggaggg ttgtggaact ggacagtgac atggtagata 2950

 tcacccagga gccagtgttg gataccatgt tagaagagag catgcctgag 3000

 gatcaggaac ctgtgtctgc ctcaacacat attgcatctt cactgggaat 3050

 taatccacat gtcttacaga tcatgaaagc atcattgctt actgatgaag 3100

 aagatgtaga tatggcactg gatcaacgct tcagtcgcct gccttccaaa 3150

 gcagatactt ctcaagaaat ctgttctccc agactcccca tttcagcatc 3200

 ccactcgtcg aaaactcgtt cactagttgg tgggttacta caatcaaaat 3250

 ttacaagtgg agcttttctt tcaccaagtg tctctgtgca agaatgtcgt 3300

 actcccagag cagcatcttt aatgaatatc ccatccacat cctcttggtc 3350

 tgtccctcca cccctgactt ctgtgttcac aatgcccagc ccagcccctg 3400

 aggttccgtt gaaaacagtg ggtacacgta ggcaactagg cctagtgcct 3450

 cgtgaaaagt ctgtcaccta tggcaaggga aaactcttga tggacatggc 3500

 cctattcatg ggacgctcat ttcgtgttgg ttggggcccc aactggactc 3550

 ttgctaatag tggagaacag ctgaatggct ctcatgaact agaaaatcat 3600

 cagattgccg attccatgga gtttggattc ctgcccaatc cagtagctgt 3650

 taaaccccta actgagtccc cattcaaagt tcacttagaa aaactcagtt 3700

 tgagacaaag aaagccagat gaagacatga aattatatca gacacctctg 3750

 gagctcaaat taaaacacag cactgtccat gtggatgaac tgtgtcctct 3800

 cattgtcccc aatctgggag ttgctgtcat tcatgactat gcagattggg 3850

 ttaaagaagc atcaggagac ttaccagaag cacaaattgt gaagcactgg 3900

 agcctgacat ggacactatg tgaagcccta tgggcccacc tgaaggagct 3950

 tgacagccag ctaaatgaac cccgtgaata cattcaaatt ctggagcgaa 4000

 gaagagcttt ctcccgctgg ctatcctgta ctgccacacc tcagattgaa 4050

 gaggaagtct ccttaaccca aaaaaacagc cctgtggagg ctgtattcag 4100

 ctacctcaca ggcaaaagga tcagtgaggc ctgctctctg gcccagcagt 4150

 caggggatca tcgtcttgct cttcttttat ctcagtttgt gggtagccag 4200

 tcagtccggg agctgctcac catgcagttg gtggactggc atcagctcca 4250

 agcagactcc ttcatccagg atgagagact gcgcatcttt gctctgttgg 4300

 ctggaaaacc ggtgtggcag ctctcagaaa agaagcaaat aaacgtgtgc 4350

 tcccagttgg attggaaacg ctccctggct atccatcttt ggtatttgct 4400

 tccaccaaca gcctccattt ctagggcgct cagcatgtat gaagaagcat 4450

 ttcagaatac ctctgacagt gacagatatg cctgctcccc acttccttcg 4500

 tatctggagg gttctggctg tgtgatagcg gaggagcaaa actcacagac 4550

 accacttcga gatgtctgct ttcaccttct aaaactctac agtgacagac 4600

 attatgatct caaccagctg ctggagcctc gaagcataac agcagatcct 4650

 ttggactacc gcctaagctg gcacttgtgg gaagtgctga gggctcttaa 4700

 ctacacccat ctctcagcgc agtgtgaagg tgtgctacag gccagttacg 4750

 ctggccagct tgaaagtgag gggctctggg agtgggccat ctttgtcctc 4800

 ctgcacattg acaactcagg catacgtgag aaggctgttc gagagctgct 4850

 tacccggcac tgccagctgt tggagacccc tgagacttgg gctaaagaga 4900

 ctttccttac ccagaagctc cgtgtacctg ccaaatggat ccacgaggcc 4950

 aaagctgtgc gagcacacat ggaatctgac aagcacttag aggccctttg 5000

 cttatttaag gctgagcact ggaaccgctg ccacaagctc atcatccgac 5050

 acttagcttc tgatgccatc attaatgaga actatgacta cctgaagggg 5100

 ttcttggaag acctggcacc tccagagcgc agcagcctaa ttcaggattg 5150

 ggaaacatct gggcttgttt acctggacta tattagagtc attgaaatgc 5200

 tccgccatat acagcaggtg gattgctcag gtaatgacct ggagcagtta 5250

 cacatcaaag tgacttcact gtgcagtcgg atagagcaga ttcagtgtta 5300

 cagtgctaaa gatcgcctgg ctcagtcaga catggccaaa cgtgtagcca 5350

 acctgctgcg cgtggtgctg agtctgcatc atcctcctga tagaacctcc 5400

 gactcaacac cagaccctca gcgagtccct ttgcgcctct tggctcccca 5450

 cattggccgg cttcccatgc ctgaggacta tgccatggac gaactgcgca 5500

 gccttaccca gtcctatctg cgagaactgg ctgttgggag cctgtgagcc 5550

 ccaggcactt tgcatcacag tcacatgccc attcacacca cacagaggtt 5600

 ccctgccttg tttggattgg cactgtttgc cattctctgg gttggctgtg 5650

 gcatctaccc tccctccctg ctgccagaag cagcatcctc cacttgttca 5700

 gggcttttct taatactgaa cgtagcataa gggcttctgg aacccagaag 5750

 aggagacagt ttaccatcct caagatcatt cagtgttttt cctttaaaaa 5800

 aatggtcaat aaagctcctt tggcagaatc ccccaaagaa ccagggtatt 5850

 ctttttccat ccctagccat tctggatctt gtgaccctcc atgccaacca 5900

 gcttccctac tcctaccctg gcccttttat actaggactc cttaggagga 5950

 gtgagacagg tgataatgga tccttaacag atgaactatc cacagaagga 6000

 agagggatcc gtctcttaag taattggtta gttaacactg aattttggag 6050

 gcaaaggagg gttggcctga gttaggaaac aaaatgggat ctttctgaca 6100

 cacttagggc agaagtgaat gcctgtcacg gagggattga tcttcagggc 6150

 tgtttttgtt cctgccttta gagttccatg aacaccatac ctttgctact 6200

 actatgtgca ggaacccttg gtcacatgtg acatgtctgt gggaagctcc 6250

 cagagtttgg tttggtccct ggttttcagt cttgctgaga ctctgtctgg 6300

 atttgcctgc agagtttgga taaaaaatgg caggttgggt aaccctccct 6350

 gttcatccca tgttagctcc aaagcatttc ccaccctcca tctacccctt 6400

 ccagaagcaa aaacaaacca tgactgaggc aggcatggag ttgggcgtta 6450

 ggggcaggca gagggccttt gctacactgc tgacagctat agggagcccc 6500

 aggtaatggc atgagatagc tggtgttagg gctatctcag gcaatatggc 6550

 cacacctggg tctttatgca tgaagataat gtaaaggttt ttattaaaaa 6600

 atatatatat gtataaataa atgatctaga tattttcctc tttttctgaa 6650

 gctactttct taaaaaataa ataaaatgtt tatagcattc ctggtaaaaa 6700

 aaa 6703

<210> 824
<211> 1800
<212> PRT
<213> Homo sapien

<400> 824
 Met Phe Asn Lys Ser Phe Gly Thr Pro Phe Gly Gly Gly Thr Gly
   1               5                  10                  15

 Gly Phe Gly Thr Thr Ser Thr Phe Gly Gln Asn Thr Gly Phe Gly
                  20                  25                  30

 Thr Thr Ser Gly Gly Ala Phe Gly Thr Ser Ala Phe Gly Ser Ser
                  35                  40                  45

 Asn Asn Thr Gly Gly Leu Phe Gly Asn Ser Gln Thr Lys Pro Gly
                  50                  55                  60

 Gly Leu Phe Gly Thr Ser Ser Phe Ser Gln Pro Ala Thr Ser Thr
                  65                  70                  75

 Ser Thr Gly Phe Gly Phe Gly Thr Ser Thr Gly Thr Ala Asn Thr
                  80                  85                  90

 Leu Phe Gly Thr Ala Ser Thr Gly Thr Ser Leu Phe Ser Ser Gln
                  95                 100                 105

 Asn Asn Ala Phe Ala Gln Asn Lys Pro Thr Gly Phe Gly Asn Phe
                 110                 115                 120

 Gly Thr Ser Thr Ser Ser Gly Gly Leu Phe Gly Thr Thr Asn Thr
                 125                 130                 135

 Thr Ser Asn Pro Phe Gly Ser Thr Ser Gly Ser Leu Phe Gly Pro
                 140                 145                 150

 Ser Ser Phe Thr Ala Ala Pro Thr Gly Thr Thr Ile Lys Phe Asn
                 155                 160                 165

 Pro Pro Thr Gly Thr Asp Thr Met Val Lys Ala Gly Val Ser Thr
                 170                 175                 180

 Asn Ile Ser Thr Lys His Gln Cys Ile Thr Ala Met Lys Glu Tyr
                 185                 190                 195

 Glu Ser Lys Ser Leu Glu Glu Leu Arg Leu Glu Asp Tyr Gln Ala
                 200                 205                 210

 Asn Arg Lys Gly Pro Gln Asn Gln Val Gly Ala Gly Thr Thr Thr
                 215                 220                 225

 Gly Leu Phe Gly Ser Ser Pro Ala Thr Ser Ser Ala Thr Gly Leu
                 230                 235                 240

 Phe Ser Ser Ser Thr Thr Asn Ser Gly Phe Ala Tyr Gly Gln Asn
                 245                 250                 255

 Lys Thr Ala Phe Gly Thr Ser Thr Thr Gly Phe Gly Thr Asn Pro
                 260                 265                 270

 Gly Gly Leu Phe Gly Gln Gln Asn Gln Gln Thr Thr Ser Leu Phe
                 275                 280                 285

 Ser Lys Pro Phe Gly Gln Ala Thr Thr Thr Gln Asn Thr Gly Phe
                 290                 295                 300

 Ser Phe Gly Asn Thr Ser Thr Ile Gly Gln Pro Ser Thr Asn Thr
                 305                 310                 315

 Met Gly Leu Phe Gly Val Thr Gln Ala Ser Gln Pro Gly Gly Leu
                 320                 325                 330

 Phe Gly Thr Ala Thr Asn Thr Ser Thr Gly Thr Ala Phe Gly Thr
                 335                 340                 345

 Gly Thr Gly Leu Phe Gly Gln Thr Asn Thr Gly Phe Gly Ala Val
                 350                 355                 360

 Gly Ser Thr Leu Phe Gly Asn Asn Lys Leu Thr Thr Phe Gly Ser
                 365                 370                 375

 Ser Thr Thr Ser Ala Pro Ser Phe Gly Thr Thr Ser Gly Gly Leu
                 380                 385                 390

 Phe Gly Phe Gly Thr Asn Thr Ser Gly Asn Ser Ile Phe Gly Ser
                 395                 400                 405

 Lys Pro Ala Pro Gly Thr Leu Gly Thr Gly Leu Gly Ala Gly Phe
                 410                 415                 420

 Gly Thr Ala Leu Gly Ala Gly Gln Ala Ser Leu Phe Gly Asn Asn
                 425                 430                 435

 Gln Pro Lys Ile Gly Gly Pro Leu Gly Thr Gly Ala Phe Gly Ala
                 440                 445                 450

 Pro Gly Phe Asn Thr Thr Thr Ala Thr Leu Gly Phe Gly Ala Pro
                 455                 460                 465

 Gln Ala Pro Val Ala Leu Thr Asp Pro Asn Ala Ser Ala Ala Gln
                 470                 475                 480

 Gln Ala Val Leu Gln Gln His Ile Asn Ser Leu Thr Tyr Ser Pro
                 485                 490                 495

 Phe Gly Asp Ser Pro Leu Phe Arg Asn Pro Met Ser Asp Pro Lys
                 500                 505                 510

 Lys Lys Glu Glu Arg Leu Lys Pro Thr Asn Pro Ala Ala Gln Lys
                 515                 520                 525

 Ala Leu Thr Thr Pro Thr His Tyr Lys Leu Thr Pro Arg Pro Ala
                 530                 535                 540

 Thr Arg Val Arg Pro Lys Ala Leu Gln Thr Thr Gly Thr Ala Lys
                 545                 550                 555

 Ser His Leu Phe Asp Gly Leu Asp Asp Asp Glu Pro Ser Leu Ala
                 560                 565                 570

 Asn Gly Ala Phe Met Pro Lys Lys Ser Ile Lys Lys Leu Val Leu
                 575                 580                 585

 Lys Asn Leu Asn Asn Ser Asn Leu Phe Ser Pro Val Asn Arg Asp
                 590                 595                 600

 Ser Glu Asn Leu Ala Ser Pro Ser Glu Tyr Pro Glu Asn Gly Glu
                 605                 610                 615

 Arg Phe Ser Phe Leu Ser Lys Pro Val Asp Glu Asn His Gln Gln
                 620                 625                 630

 Asp Gly Asp Glu Asp Ser Leu Val Ser His Phe Tyr Thr Asn Pro
                 635                 640                 645

 Ile Ala Lys Pro Ile Pro Gln Thr Pro Glu Ser Ala Gly Asn Lys
                 650                 655                 660

 His Ser Asn Ser Asn Ser Val Asp Asp Thr Ile Val Ala Leu Asn
                 665                 670                 675

 Met Arg Ala Ala Leu Arg Asn Gly Leu Glu Gly Ser Ser Glu Glu
                 680                 685                 690

 Thr Ser Phe His Asp Glu Ser Leu Gln Asp Asp Arg Glu Glu Ile
                 695                 700                 705

 Glu Asn Asn Ser Tyr His Met His Pro Ala Gly Ile Ile Leu Thr
                 710                 715                 720

 Lys Val Gly Tyr Tyr Thr Ile Pro Ser Met Asp Asp Leu Ala Lys
                 725                 730                 735

 Ile Thr Asn Glu Lys Gly Glu Cys Ile Val Ser Asp Phe Thr Ile
                 740                 745                 750

 Gly Arg Lys Gly Tyr Gly Ser Ile Tyr Phe Glu Gly Asp Val Asn
                 755                 760                 765

 Leu Thr Asn Leu Asn Leu Asp Asp Ile Val His Ile Arg Arg Lys
                 770                 775                 780

 Glu Val Val Val Tyr Leu Asp Asp Asn Gln Lys Pro Pro Val Gly
                 785                 790                 795

 Glu Gly Leu Asn Arg Lys Ala Glu Val Thr Leu Asp Gly Val Trp
                 800                 805                 810

 Pro Thr Asp Lys Thr Ser Arg Cys Leu Ile Lys Ser Pro Asp Arg
                 815                 820                 825

 Leu Ala Asp Ile Asn Tyr Glu Gly Arg Leu Glu Ala Val Ser Arg
                 830                 835                 840

 Lys Gln Gly Ala Gln Phe Lys Glu Tyr Arg Pro Glu Thr Gly Ser
                 845                 850                 855

 Trp Val Phe Lys Val Ser His Phe Ser Lys Tyr Gly Leu Gln Asp
                 860                 865                 870

 Ser Asp Glu Glu Glu Glu Glu His Pro Ser Lys Thr Ser Thr Lys
                 875                 880                 885

 Lys Leu Lys Thr Ala Pro Leu Pro Pro Ala Ser Gln Thr Thr Pro
                 890                 895                 900

 Leu Gln Met Ala Leu Asn Gly Lys Pro Ala Pro Pro Pro Gln Ser
                 905                 910                 915

 Gln Ser Pro Glu Val Glu Gln Leu Gly Arg Val Val Glu Leu Asp
                 920                 925                 930

 Ser Asp Met Val Asp Ile Thr Gln Glu Pro Val Leu Asp Thr Met
                 935                 940                 945

 Leu Glu Glu Ser Met Pro Glu Asp Gln Glu Pro Val Ser Ala Ser
                 950                 955                 960

 Thr His Ile Ala Ser Ser Leu Gly Ile Asn Pro His Val Leu Gln
                 965                 970                 975

 Ile Met Lys Ala Ser Leu Leu Thr Asp Glu Glu Asp Val Asp Met
                 980                 985                 990

 Ala Leu Asp Gln Arg Phe Ser Arg Leu Pro Ser Lys Ala Asp Thr
                 995                1000                1005

 Ser Gln Glu Ile Cys Ser Pro Arg Leu Pro Ile Ser Ala Ser His
                1010                1015                1020

 Ser Ser Lys Thr Arg Ser Leu Val Gly Gly Leu Leu Gln Ser Lys
                1025                1030                1035

 Phe Thr Ser Gly Ala Phe Leu Ser Pro Ser Val Ser Val Gln Glu
                1040                1045                1050

 Cys Arg Thr Pro Arg Ala Ala Ser Leu Met Asn Ile Pro Ser Thr
                1055                1060                1065

 Ser Ser Trp Ser Val Pro Pro Pro Leu Thr Ser Val Phe Thr Met
                1070                1075                1080

 Pro Ser Pro Ala Pro Glu Val Pro Leu Lys Thr Val Gly Thr Arg
                1085                1090                1095

 Arg Gln Leu Gly Leu Val Pro Arg Glu Lys Ser Val Thr Tyr Gly
                1100                1105                1110

 Lys Gly Lys Leu Leu Met Asp Met Ala Leu Phe Met Gly Arg Ser
                1115                1120                1125

 Phe Arg Val Gly Trp Gly Pro Asn Trp Thr Leu Ala Asn Ser Gly
                1130                1135                1140

 Glu Gln Leu Asn Gly Ser His Glu Leu Glu Asn His Gln Ile Ala
                1145                1150                1155

 Asp Ser Met Glu Phe Gly Phe Leu Pro Asn Pro Val Ala Val Lys
                1160                1165                1170

 Pro Leu Thr Glu Ser Pro Phe Lys Val His Leu Glu Lys Leu Ser
                1175                1180                1185

 Leu Arg Gln Arg Lys Pro Asp Glu Asp Met Lys Leu Tyr Gln Thr
                1190                1195                1200

 Pro Leu Glu Leu Lys Leu Lys His Ser Thr Val His Val Asp Glu
                1205                1210                1215

 Leu Cys Pro Leu Ile Val Pro Asn Leu Gly Val Ala Val Ile His
                1220                1225                1230

 Asp Tyr Ala Asp Trp Val Lys Glu Ala Ser Gly Asp Leu Pro Glu
                1235                1240                1245

 Ala Gln Ile Val Lys His Trp Ser Leu Thr Trp Thr Leu Cys Glu
                1250                1255                1260

 Ala Leu Trp Ala His Leu Lys Glu Leu Asp Ser Gln Leu Asn Glu
                1265                1270                1275

 Pro Arg Glu Tyr Ile Gln Ile Leu Glu Arg Arg Arg Ala Phe Ser
                1280                1285                1290

 Arg Trp Leu Ser Cys Thr Ala Thr Pro Gln Ile Glu Glu Glu Val
                1295                1300                1305

 Ser Leu Thr Gln Lys Asn Ser Pro Val Glu Ala Val Phe Ser Tyr
                1310                1315                1320

 Leu Thr Gly Lys Arg Ile Ser Glu Ala Cys Ser Leu Ala Gln Gln
                1325                1330                1335

 Ser Gly Asp His Arg Leu Ala Leu Leu Leu Ser Gln Phe Val Gly
                1340                1345                1350

 Ser Gln Ser Val Arg Glu Leu Leu Thr Met Gln Leu Val Asp Trp
                1355                1360                1365

 His Gln Leu Gln Ala Asp Ser Phe Ile Gln Asp Glu Arg Leu Arg
                1370                1375                1380

 Ile Phe Ala Leu Leu Ala Gly Lys Pro Val Trp Gln Leu Ser Glu
                1385                1390                1395

 Lys Lys Gln Ile Asn Val Cys Ser Gln Leu Asp Trp Lys Arg Ser
                1400                1405                1410

 Leu Ala Ile His Leu Trp Tyr Leu Leu Pro Pro Thr Ala Ser Ile
                1415                1420                1425

 Ser Arg Ala Leu Ser Met Tyr Glu Glu Ala Phe Gln Asn Thr Ser
                1430                1435                1440

 Asp Ser Asp Arg Tyr Ala Cys Ser Pro Leu Pro Ser Tyr Leu Glu
                1445                1450                1455

 Gly Ser Gly Cys Val Ile Ala Glu Glu Gln Asn Ser Gln Thr Pro
                1460                1465                1470

 Leu Arg Asp Val Cys Phe His Leu Leu Lys Leu Tyr Ser Asp Arg
                1475                1480                1485

 His Tyr Asp Leu Asn Gln Leu Leu Glu Pro Arg Ser Ile Thr Ala
                1490                1495                1500

 Asp Pro Leu Asp Tyr Arg Leu Ser Trp His Leu Trp Glu Val Leu
                1505                1510                1515

 Arg Ala Leu Asn Tyr Thr His Leu Ser Ala Gln Cys Glu Gly Val
                1520                1525                1530

 Leu Gln Ala Ser Tyr Ala Gly Gln Leu Glu Ser Glu Gly Leu Trp
                1535                1540                1545

 Glu Trp Ala Ile Phe Val Leu Leu His Ile Asp Asn Ser Gly Ile
                1550                1555                1560

 Arg Glu Lys Ala Val Arg Glu Leu Leu Thr Arg His Cys Gln Leu
                1565                1570                1575

 Leu Glu Thr Pro Glu Thr Trp Ala Lys Glu Thr Phe Leu Thr Gln
                1580                1585                1590

 Lys Leu Arg Val Pro Ala Lys Trp Ile His Glu Ala Lys Ala Val
                1595                1600                1605

 Arg Ala His Met Glu Ser Asp Lys His Leu Glu Ala Leu Cys Leu
                1610                1615                1620

 Phe Lys Ala Glu His Trp Asn Arg Cys His Lys Leu Ile Ile Arg
                1625                1630                1635

 His Leu Ala Ser Asp Ala Ile Ile Asn Glu Asn Tyr Asp Tyr Leu
                1640                1645                1650

 Lys Gly Phe Leu Glu Asp Leu Ala Pro Pro Glu Arg Ser Ser Leu
                1655                1660                1665

 Ile Gln Asp Trp Glu Thr Ser Gly Leu Val Tyr Leu Asp Tyr Ile
                1670                1675                1680

 Arg Val Ile Glu Met Leu Arg His Ile Gln Gln Val Asp Cys Ser
                1685                1690                1695

 Gly Asn Asp Leu Glu Gln Leu His Ile Lys Val Thr Ser Leu Cys
                1700                1705                1710

 Ser Arg Ile Glu Gln Ile Gln Cys Tyr Ser Ala Lys Asp Arg Leu
                1715                1720                1725

 Ala Gln Ser Asp Met Ala Lys Arg Val Ala Asn Leu Leu Arg Val
                1730                1735                1740

 Val Leu Ser Leu His His Pro Pro Asp Arg Thr Ser Asp Ser Thr
                1745                1750                1755

 Pro Asp Pro Gln Arg Val Pro Leu Arg Leu Leu Ala Pro His Ile
                1760                1765                1770

 Gly Arg Leu Pro Met Pro Glu Asp Tyr Ala Met Asp Glu Leu Arg
                1775                1780                1785

 Ser Leu Thr Gln Ser Tyr Leu Arg Glu Leu Ala Val Gly Ser Leu
                1790                1795                1800

<210> 825
<211> 2097
<212> DNA
<213> Homo sapien

<400> 825
 gtaagtgcca gggtctcagg gtcaggtcgc ggctggtcac tgtgcaggcg 50

 cttgggtgac gcgacgatct cagcggatct ggtcaccttc gtctccccgc 100

 catggagacc tcagcactca agcagcagga gcagcccgcg gcgaccaaga 150

 tcaggaacct gccctgggtt gaaaaatacc ggccacagac cctgaatgat 200

 ctcatttctc atcaggacat tctgagtacc attcagaagt ttatcaatga 250

 agaccgactg ccacacttgc ttctctacgg tcccccaggg acaggcaaga 300

 catctaccat cctagcctgt gcgaaacagc tatataaaga caaagaattt 350

 ggctccatgg tcttggagct gaatgcttca gatgaccgag gaatagacat 400

 cattcgagga ccgatcctga gctttgctag cacaaggaca atatttaaga 450

 aaggctttaa gctagtgatc ttggatgaag cagacgccat gactcaggac 500

 gcccagaatg ccttgagaag agtaattgag aaattcacag aaaataccag 550

 attctgcctc atctgtaact atctgtcaaa gatcatccct gccttgcagt 600

 cccgctgcac gaggtttcgg ttcggtcccc tgactcctga actcatggtt 650

 ccccgcctgg aacatgtcgt ggaagaagag aaagttgata taagtgaaga 700

 tggaatgaaa gcactagtca ctctttccag tggagacatg cgtagggctc 750

 tgaacatttt gcagagcacc aatatggcct ttgggaaggt gacagaggag 800

 actgtctaca cctgcaccgg gcacccgctc aagtcagaca ttgccaacat 850

 cctggactgg atgttgaatc aagatttcac cacagcctac agaaatatta 900

 cagagttgaa aactctgaag gggttggcac tgcatgatat cctgacagag 950

 atacacttgt ttgtgcatag agttgacttt ccatcttcag ttcgaataca 1000

 tttattgacc aaaatggcag acattgagta caggctttct gttggcacca 1050

 acgagaagat ccagctgagc tccctcattg ctgcatttca agtcaccaga 1100

 gacctgattg ttgcagaggc ctagatgctc tgagggccat tcacaattct 1150

 cagggctcag cagtgatggg agaacagagg acagttccag gataaactgc 1200

 tgcctggggc tgtgggatga atcagtcacc ccgaatcttg gaaaaacccc 1250

 cttccaggag aggatgggca ggcatttaaa aagtaccatt tttgtggttg 1300

 tttggagcag ggatgtacaa aataatttta atgtattaac tcatactgcc 1350

 tgtcttttat aggggaaaaa aataaccttt tttattttaa agttataagg 1400

 tttttacctt ttagttgctt ggatgacagg gaattagcct accccatttt 1450

 ggtctggaac agaagacttt caaatttaat atggtccaag tgtcttccta 1500

 ctcaaggtaa acattatctc caaaattaca tttatgattc taatatttgg 1550

 cattgtgtct gtatctaatt taaacagatg ttaatggacg tctggccgaa 1600

 actattatac ttttataaga tgagctgaat cctcttactt taaaaactgg 1650

 tctttttatt taccctctgt ggtagaagag tcaccagcag gttccaaatt 1700

 gatgtgtatg ataggaaaaa aaccttaatt ttaaatataa tatagagcct 1750

 taaactatgc cactgggtgg cagaggctgt ataaaacgca cttgttttca 1800

 tgcaggagcg gggcaagtaa ggttgagcct gactgtaaac ctagaactgc 1850

 ggaaggactg ggacttttgt acaaatttca catttatttt acagcaatca 1900

 tgctgcattt gtgttagtgt tctttataat aaaaaacaaa gcagcctcct 1950

 ggctggctgt gttacaagtg actcttcctt agacagctag aaagatgctg 2000

 actttgtcaa acttgcattt atatgaaaac cttctgtctc taatatcaca 2050

 gaataaactt tctttagatg ctgttcttta aaaaaaaaaa aaaaaaa 2097

<210> 826
<211> 340
<212> PRT
<213> Homo sapien

<400> 826
 Met Glu Thr Ser Ala Leu Lys Gln Gln Glu Gln Pro Ala Ala Thr
   1               5                  10                  15

 Lys Ile Arg Asn Leu Pro Trp Val Glu Lys Tyr Arg Pro Gln Thr
                  20                  25                  30

 Leu Asn Asp Leu Ile Ser His Gln Asp Ile Leu Ser Thr Ile Gln
                  35                  40                  45

 Lys Phe Ile Asn Glu Asp Arg Leu Pro His Leu Leu Leu Tyr Gly
                  50                  55                  60

 Pro Pro Gly Thr Gly Lys Thr Ser Thr Ile Leu Ala Cys Ala Lys
                  65                  70                  75

 Gln Leu Tyr Lys Asp Lys Glu Phe Gly Ser Met Val Leu Glu Leu
                  80                  85                  90

 Asn Ala Ser Asp Asp Arg Gly Ile Asp Ile Ile Arg Gly Pro Ile
                  95                 100                 105

 Leu Ser Phe Ala Ser Thr Arg Thr Ile Phe Lys Lys Gly Phe Lys
                 110                 115                 120

 Leu Val Ile Leu Asp Glu Ala Asp Ala Met Thr Gln Asp Ala Gln
                 125                 130                 135

 Asn Ala Leu Arg Arg Val Ile Glu Lys Phe Thr Glu Asn Thr Arg
                 140                 145                 150

 Phe Cys Leu Ile Cys Asn Tyr Leu Ser Lys Ile Ile Pro Ala Leu
                 155                 160                 165

 Gln Ser Arg Cys Thr Arg Phe Arg Phe Gly Pro Leu Thr Pro Glu
                 170                 175                 180

 Leu Met Val Pro Arg Leu Glu His Val Val Glu Glu Glu Lys Val
                 185                 190                 195

 Asp Ile Ser Glu Asp Gly Met Lys Ala Leu Val Thr Leu Ser Ser
                 200                 205                 210

 Gly Asp Met Arg Arg Ala Leu Asn Ile Leu Gln Ser Thr Asn Met
                 215                 220                 225

 Ala Phe Gly Lys Val Thr Glu Glu Thr Val Tyr Thr Cys Thr Gly
                 230                 235                 240

 His Pro Leu Lys Ser Asp Ile Ala Asn Ile Leu Asp Trp Met Leu
                 245                 250                 255

 Asn Gln Asp Phe Thr Thr Ala Tyr Arg Asn Ile Thr Glu Leu Lys
                 260                 265                 270

 Thr Leu Lys Gly Leu Ala Leu His Asp Ile Leu Thr Glu Ile His
                 275                 280                 285

 Leu Phe Val His Arg Val Asp Phe Pro Ser Ser Val Arg Ile His
                 290                 295                 300

 Leu Leu Thr Lys Met Ala Asp Ile Glu Tyr Arg Leu Ser Val Gly
                 305                 310                 315

 Thr Asn Glu Lys Ile Gln Leu Ser Ser Leu Ile Ala Ala Phe Gln
                 320                 325                 330

 Val Thr Arg Asp Leu Ile Val Ala Glu Ala
                 335                 340

<210> 827
<211> 4681
<212> DNA
<213> Homo sapien

<400> 827
 ctccttccat aagggtctgg tccttcatcc ctcccgcttc accagacccc 50

 ctcaccctgg gagccgccac ctccctttcc ccaagaccag atgtcgcgcg 100

 gccggacaca gccagcacgg agagtcgatg ccggcgtctg agctgcgcag 150

 tggggtcttc ccgctgccca gcagcctaca ggcgcggtgc actctggggg 200

 aacatggccg cttccggtct ccctcccggg ccggcgctgg cctgactgcg 250

 gccccggtcc gtagcactcc gccctccgct tctcccgccc tgtagccgcg 300

 aagactgctt cagcctttcc ctgtgctgcc cctgccgcgc gatggagacg 350

 agctcgagct gcgagagtct tggctcccag ccggcggcgg ctcggccgcc 400

 cagcgtggac tccttgtcca gtgcctccac ttctcattca gagaattcag 450

 tgcatacaaa atcagcttct gttgtatcat cagattccat ttcaacttct 500

 gccgacaact tttctcctga tttgagggtc ctgagggagt ctaacaagtt 550

 agcagaaatg gaagaaccac ccttgcttcc aggagaaaat attaaagaca 600

 tggccaaaga tgtaacttat atatgtccat tcactggcgc tgtacgagga 650

 actctgactg tcacgaatta taggttatat ttcaaaagca tggaacggga 700

 tcccccattt gttttagatg cttcccttgg tgtgataaat agagtagaaa 750

 aaattggtgg tgcttctagt cgaggtgaaa attcttatgg actagaaact 800

 gtgtgtaagg atattaggaa tttacgattt gctcataaac ctgaggggcg 850

 gacaagaaga tccatatttg agaatctaat gaaatatgca tttcctgtct 900

 ctaataacct gcctcttttt gcttttgaat acaaagaagt attccctgaa 950

 aatgggtgga agctatatga ccctctttta gagtatagaa ggcagggaat 1000

 tccaaatgaa agctggagaa taacaaagat aaatgaacga tatgaacttt 1050

 gtgatacata ccctgccctc ctggttgtgc cagcaaatat tcctgatgaa 1100

 gaattaaaga gagtggcatc cttcagatca agaggccgta tcccagtttt 1150

 atcatggatt catcctgaaa gtcaagccac aatcactcgg tgtagccagc 1200

 ccatggttgg agtgagtgga aagcgaagca aagaagatga aaaatacctt 1250

 caagctatca tggattccaa tgcccagtct cacaaaatct ttatatttga 1300

 tgcccggcca agtgttaatg ctgttgccaa caaggcaaag ggtggaggtt 1350

 atgaaagtga agatgcctat caaaatgctg aactagtttt cctggatatc 1400

 cacaatattc atgttatgag agaatcatta cgaaaactta aggagattgt 1450

 gtaccccaac attgaggaaa ctcactggtt gtctaacttg gaatctactc 1500

 attggctaga acatattaag cttattcttg caggggctct taggattgct 1550

 gacaaggtag agtcagggaa gacgtctgtg gtagtgcatt gcagtgatgg 1600

 ttgggatcgc acagctcagc tcacttccct tgccatgctc atgttggatg 1650

 gatactatcg aaccatccga ggatttgaag tccttgtgga gaaagaatgg 1700

 ctaagttttg gacatcgatt tcaactaaga gttggccatg gagataagaa 1750

 ccatgcagat gcagacagat cgcctgtttt tcttcaattt attgactgtg 1800

 tctggcagat gacaagacag tttcctaccg catttgaatt caatgagtat 1850

 tttctcatta ccattttgga ccacctatac agctgcttat tcggaacatt 1900

 cctctgtaat agtgaacaac agagaggaaa agagaatctt cctaaaagga 1950

 ctgtgtcact gtggtcttac ataaacagcc agctggaaga cttcactaat 2000

 cctctctatg ggagctattc caatcatgtc ctttatccag tagccagcat 2050

 gcgccaccta gagctctggg tgggatatta cataaggtgg aatccacgga 2100

 tgaaaccaca ggaacctatt cacaacagat acaaagaact tcttgctaaa 2150

 cgagcagagc ttcagaaaaa agtagaggaa ctacagagag agatttctaa 2200

 ccgatcaacc tcatcctcag agagagccag ctctcctgca cagtgtgtca 2250

 ctcctgtcca aactgttgta taaaggactg taagatcagg ggcatcattg 2300

 ctatacactc ttgattacac tggcagctct atgagtagaa agtcttcgga 2350

 atttagaacc catctatgag agaaagttca gtcactttat ttattttaaa 2400

 tctctctagg atgagtttag aactgtagca gtgcaggtgg cttaagtgaa 2450

 gtaactccat atgtaattac atgattatga tactaatctt ttaagtatcc 2500

 aaagaatatt aaaatacttc aatcctggat tcacagtggg aacaagtttc 2550

 tattaaaagg caaatgctgt tacaaatttt tggcatctgg taatattaaa 2600

 accattttag aaatacactc tgtgctcact gtgcagagga acatcagttt 2650

 tcaaaccaac actgaaattc tgtggcatca catatattgg gccttgatgt 2700

 catgacagat caaaatcatt tgatatccct ttctccattc taggtttttc 2750

 tttttttcag taactgattt accttgatca cttttcaact tccatattct 2800

 tcatatagta aaaggcaaag tattgaagat actacggtgt ggtagtagtt 2850

 gaaaattatt gccgtcatta tttacatact taagacatat tagcaagttg 2900

 atccaaaatg ggaggcctta tagatgtgct tgggggaaaa tgaaggggag 2950

 aaagtagcca tacaggagtt caaagaattc catgcccttc agattagccc 3000

 aattaccaga aacatcatga aagatatttt aaaaactaat tatttactac 3050

 agtgtatttc acttgtcttg tgtgtctgaa cacacagaag ctaattagca 3100

 agtttttaag aagtatttaa aaatcttact aggattgaca ttttttctga 3150

 attctgtata aatagcttat agtgagaagt actgtgctca aattttacat 3200

 ttttttcctt tgcaaattct gtaatttcac tcaacgatta agtctaccaa 3250

 agaacacact gcatgtaaaa gatgtattac aatctcaaag ccagtaaaag 3300

 aaatcttgct tcactgttca cctgctacaa gtaagagttt ggtgctggta 3350

 gaaacatttg actctgatgt ctattttatt ctacataaga gccatatgta 3400

 atgtactgta acaaaggagc ttcttgtccc cttggtcttt taattaaaag 3450

 aaattccaac tgacttttaa actttgttct tgtccaaagt tgccatttct 3500

 tttttttccc cagaaatatt tggaaattat tggaggaata tgcaccccag 3550

 atgaaaatgt tcagtttgta cccatttttc cttaaccaac acccaaatca 3600

 aacaattaaa atatacagtg tttttccact cactaattca ctatacagag 3650

 agtctgaacc ttagcctccc tcttggtctt gcagtgagga aatttctatt 3700

 agtatatcca atttagcaaa attggtacca aaatgatttc tttggtaatt 3750

 gtgtgaaata taagcttttt aacagggcat ttaagtggct agcaaatcag 3800

 taattaaaaa ttaagctttc tactccaagt atttcacaaa tgcatctgcc 3850

 attttcctca tttaaacctt ggttatcttg gcctgatacc acataaaaga 3900

 atgtagaatg gctgaagaga tcaagaattt aaagcttcta gtcttaacat 3950

 acttgcatcc acttcaaatt caaatcaaaa gccagggaaa tctaagtgca 4000

 accctaccac ttctctgctg agaaccttcc agtggttccc ctcaccttct 4050

 gcagaagtct ccaatatgga gtacatgcac ttgggcattt aatatatacc 4100

 actggtgtgt gtgggaggga gggaggagga atactagccc tttttatata 4150

 tttacacaag caaaactttt aaatatttga attgacagtt acatgtttca 4200

 taacttcgta tgtctattgg ttgtgcaggt gtaatttttt ccctttttga 4250

 ttagggttac aaaatttaga gaccagtatg attaagttga agctccttag 4300

 cctccttcga cctagtctct gcatacctca acttttacgt accaatgcta 4350

 ctctgctgtt cacaattgcc tcatgtaatc tgcagattcc tgcctcccca 4400

 ctttggttca gtctgtcttg tgcacctgga acaactgttc tcccttgtga 4450

 ctaattccta ttttctagag tttaggcatc atctcttcct ttgggaagtt 4500

 atctgattca cgactgcctt ctctgacatc cccaccttcc tctgtgcccc 4550

 catagcactg tgtataccgc tactaccact gcaattcaca ttatattgga 4600

 atgaacaatt cacatgtcta ccacaagtct gtaaacataa ccttatttga 4650

 aatgaattgc aataaagctc tgttacaacg t 4681

<210> 828
<211> 643
<212> PRT
<213> Homo sapien

<400> 828
 Met Glu Thr Ser Ser Ser Cys Glu Ser Leu Gly Ser Gln Pro Ala
   1               5                  10                  15

 Ala Ala Arg Pro Pro Ser Val Asp Ser Leu Ser Ser Ala Ser Thr
                  20                  25                  30

 Ser His Ser Glu Asn Ser Val His Thr Lys Ser Ala Ser Val Val
                  35                  40                  45

 Ser Ser Asp Ser Ile Ser Thr Ser Ala Asp Asn Phe Ser Pro Asp
                  50                  55                  60

 Leu Arg Val Leu Arg Glu Ser Asn Lys Leu Ala Glu Met Glu Glu
                  65                  70                  75

 Pro Pro Leu Leu Pro Gly Glu Asn Ile Lys Asp Met Ala Lys Asp
                  80                  85                  90

 Val Thr Tyr Ile Cys Pro Phe Thr Gly Ala Val Arg Gly Thr Leu
                  95                 100                 105

 Thr Val Thr Asn Tyr Arg Leu Tyr Phe Lys Ser Met Glu Arg Asp
                 110                 115                 120

 Pro Pro Phe Val Leu Asp Ala Ser Leu Gly Val Ile Asn Arg Val
                 125                 130                 135

 Glu Lys Ile Gly Gly Ala Ser Ser Arg Gly Glu Asn Ser Tyr Gly
                 140                 145                 150

 Leu Glu Thr Val Cys Lys Asp Ile Arg Asn Leu Arg Phe Ala His
                 155                 160                 165

 Lys Pro Glu Gly Arg Thr Arg Arg Ser Ile Phe Glu Asn Leu Met
                 170                 175                 180

 Lys Tyr Ala Phe Pro Val Ser Asn Asn Leu Pro Leu Phe Ala Phe
                 185                 190                 195

 Glu Tyr Lys Glu Val Phe Pro Glu Asn Gly Trp Lys Leu Tyr Asp
                 200                 205                 210

 Pro Leu Leu Glu Tyr Arg Arg Gln Gly Ile Pro Asn Glu Ser Trp
                 215                 220                 225

 Arg Ile Thr Lys Ile Asn Glu Arg Tyr Glu Leu Cys Asp Thr Tyr
                 230                 235                 240

 Pro Ala Leu Leu Val Val Pro Ala Asn Ile Pro Asp Glu Glu Leu
                 245                 250                 255

 Lys Arg Val Ala Ser Phe Arg Ser Arg Gly Arg Ile Pro Val Leu
                 260                 265                 270

 Ser Trp Ile His Pro Glu Ser Gln Ala Thr Ile Thr Arg Cys Ser
                 275                 280                 285

 Gln Pro Met Val Gly Val Ser Gly Lys Arg Ser Lys Glu Asp Glu
                 290                 295                 300

 Lys Tyr Leu Gln Ala Ile Met Asp Ser Asn Ala Gln Ser His Lys
                 305                 310                 315

 Ile Phe Ile Phe Asp Ala Arg Pro Ser Val Asn Ala Val Ala Asn
                 320                 325                 330

 Lys Ala Lys Gly Gly Gly Tyr Glu Ser Glu Asp Ala Tyr Gln Asn
                 335                 340                 345

 Ala Glu Leu Val Phe Leu Asp Ile His Asn Ile His Val Met Arg
                 350                 355                 360

 Glu Ser Leu Arg Lys Leu Lys Glu Ile Val Tyr Pro Asn Ile Glu
                 365                 370                 375

 Glu Thr His Trp Leu Ser Asn Leu Glu Ser Thr His Trp Leu Glu
                 380                 385                 390

 His Ile Lys Leu Ile Leu Ala Gly Ala Leu Arg Ile Ala Asp Lys
                 395                 400                 405

 Val Glu Ser Gly Lys Thr Ser Val Val Val His Cys Ser Asp Gly
                 410                 415                 420

 Trp Asp Arg Thr Ala Gln Leu Thr Ser Leu Ala Met Leu Met Leu
                 425                 430                 435

 Asp Gly Tyr Tyr Arg Thr Ile Arg Gly Phe Glu Val Leu Val Glu
                 440                 445                 450

 Lys Glu Trp Leu Ser Phe Gly His Arg Phe Gln Leu Arg Val Gly
                 455                 460                 465

 His Gly Asp Lys Asn His Ala Asp Ala Asp Arg Ser Pro Val Phe
                 470                 475                 480

 Leu Gln Phe Ile Asp Cys Val Trp Gln Met Thr Arg Gln Phe Pro
                 485                 490                 495

 Thr Ala Phe Glu Phe Asn Glu Tyr Phe Leu Ile Thr Ile Leu Asp
                 500                 505                 510

 His Leu Tyr Ser Cys Leu Phe Gly Thr Phe Leu Cys Asn Ser Glu
                 515                 520                 525

 Gln Gln Arg Gly Lys Glu Asn Leu Pro Lys Arg Thr Val Ser Leu
                 530                 535                 540

 Trp Ser Tyr Ile Asn Ser Gln Leu Glu Asp Phe Thr Asn Pro Leu
                 545                 550                 555

 Tyr Gly Ser Tyr Ser Asn His Val Leu Tyr Pro Val Ala Ser Met
                 560                 565                 570

 Arg His Leu Glu Leu Trp Val Gly Tyr Tyr Ile Arg Trp Asn Pro
                 575                 580                 585

 Arg Met Lys Pro Gln Glu Pro Ile His Asn Arg Tyr Lys Glu Leu
                 590                 595                 600

 Leu Ala Lys Arg Ala Glu Leu Gln Lys Lys Val Glu Glu Leu Gln
                 605                 610                 615

 Arg Glu Ile Ser Asn Arg Ser Thr Ser Ser Ser Glu Arg Ala Ser
                 620                 625                 630

 Ser Pro Ala Gln Cys Val Thr Pro Val Gln Thr Val Val
                 635                 640

<210> 829
<211> 1894
<212> DNA
<213> Homo sapien

<400> 829
 tcgcacttgg cttcaaagct ggctcttgga aattgagcgg agagcgacgc 50

 ggttgttgta gctgccgctg cggccgccgc ggaataataa gccgggatct 100

 accataccca ttgactaact atggaagatt ataccaaaat agagaaaatt 150

 ggagaaggta cctatggagt tgtgtataag ggtagacaca aaactacagg 200

 tcaagtggta gccatgaaaa aaatcagact agaaagtgaa gaggaagggg 250

 ttcctagtac tgcaattcgg gaaatttctc tattaaagga acttcgtcat 300

 ccaaatatag tcagtcttca ggatgtgctt atgcaggatt ccaggttata 350

 tctcatcttt gagtttcttt ccatggatct gaagaaatac ttggattcta 400

 tccctcctgg tcagtacatg gattcttcac ttgttaagag ttatttatac 450

 caaatcctac aggggattgt gttttgtcac tctagaagag ttcttcacag 500

 agacttaaaa cctcaaaatc tcttgattga tgacaaagga acaattaaac 550

 tggctgattt tggccttgcc agagcttttg gaatacctat cagagtatat 600

 acacatgagg tagtaacact ctggtacaga tctccagaag tattgctggg 650

 gtcagctcgt tactcaactc cagttgacat ttggagtata ggcaccatat 700

 ttgctgaact agcaactaag aaaccacttt tccatgggga ttcagaaatt 750

 gatcaactct tcaggatttt cagagctttg ggcactccca ataatgaagt 800

 gtggccagaa gtggaatctt tacaggacta taagaataca tttcccaaat 850

 ggaaaccagg aagcctagca tcccatgtca aaaacttgga tgaaaatggc 900

 ttggatttgc tctcgaaaat gttaatctat gatccagcca aacgaatttc 950

 tggcaaaatg gcactgaatc atccatattt taatgatttg gacaatcaga 1000

 ttaagaagat gtagctttct gacaaaaagt ttccatatgt tatgtcaaca 1050

 gatagttgtg tttttattgt taactcttgt ctatttttgt cttatatata 1100

 tttctttgtt atcaaacttc agctgtactt cgtcttctaa tttcaaaaat 1150

 ataacttaaa aatgtaaata ttctatatga atttaaatat aattctgtaa 1200

 atgtgtgtag gtctcactgt aacaactatt tgttactata ataaaactat 1250

 aatattgatg tcaggaatca ggaaaaaatt tgagttggct taaatcatct 1300

 cagtccttat ggcagtttta ttttcctgta gttggaacta ctaaaattta 1350

 ggaaaatgct aagttcaagt ttcgtaatgc tttgaagtat ttttatgctc 1400

 tgaatgttta aatgttctca tcagtttctt gccatgttgt taactataca 1450

 acctggctaa agatgaatat ttttctactg gtattttaat ttttgaccta 1500

 aatgtttaag cattcggaat gagaaaacta tacagatttg agaaatgatg 1550

 ctaaatttat aggagttttc agtaacttaa aaagctaaca tgagagcatg 1600

 ccaaaatttg ctaagtctta caaagatcaa gggctgtccg caacagggaa 1650

 gaacagtttt gaaaatttat gaactatctt atttttaggt aggttttgaa 1700

 agctttttgt ctaagtgaat tcttatgcct tggtcagagt aataactgaa 1750

 ggaggtgctt atcttggctt tcgagtctga gtttaaaact acacattttg 1800

 acatagtgtt tattagcagc catctaaaaa ggctctaatg tatatttaac 1850

 taaaattact agctttggga attaaactgt ttaacaaatt agga 1894

<210> 830
<211> 337
<212> PRT
<213> Homo sapien

<400> 830
 Ala Leu Gly Phe Lys Ala Gly Ser Trp Lys Leu Ser Gly Glu Arg
   1               5                  10                  15

 Arg Gly Cys Cys Ser Cys Arg Cys Gly Arg Arg Gly Ile Ile Ser
                  20                  25                  30

 Arg Asp Leu Pro Tyr Pro Leu Thr Asn Tyr Gly Arg Leu Tyr Gln
                  35                  40                  45

 Asn Arg Glu Lys Ile Gly Glu Gly Thr Tyr Gly Val Val Tyr Lys
                  50                  55                  60

 Gly Arg His Lys Thr Thr Gly Gln Val Val Ala Met Lys Lys Ile
                  65                  70                  75

 Arg Leu Glu Ser Glu Glu Glu Gly Val Pro Ser Thr Ala Ile Arg
                  80                  85                  90

 Glu Ile Ser Leu Leu Lys Glu Leu Arg His Pro Asn Ile Val Ser
                  95                 100                 105

 Leu Gln Asp Val Leu Met Gln Asp Ser Arg Leu Tyr Leu Ile Phe
                 110                 115                 120

 Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr Leu Asp Ser Ile Pro
                 125                 130                 135

 Pro Gly Gln Tyr Met Asp Ser Ser Leu Val Lys Ser Tyr Leu Tyr
                 140                 145                 150

 Gln Ile Leu Gln Gly Ile Val Phe Cys His Ser Arg Arg Val Leu
                 155                 160                 165

 His Arg Asp Leu Lys Pro Gln Asn Leu Leu Ile Asp Asp Lys Gly
                 170                 175                 180

 Thr Ile Lys Leu Ala Asp Phe Gly Leu Ala Arg Ala Phe Gly Ile
                 185                 190                 195

 Pro Ile Arg Val Tyr Thr His Glu Val Val Thr Leu Trp Tyr Arg
                 200                 205                 210

 Ser Pro Glu Val Leu Leu Gly Ser Ala Arg Tyr Ser Thr Pro Val
                 215                 220                 225

 Asp Ile Trp Ser Ile Gly Thr Ile Phe Ala Glu Leu Ala Thr Lys
                 230                 235                 240

 Lys Pro Leu Phe His Gly Asp Ser Glu Ile Asp Gln Leu Phe Arg
                 245                 250                 255

 Ile Phe Arg Ala Leu Gly Thr Pro Asn Asn Glu Val Trp Pro Glu
                 260                 265                 270

 Val Glu Ser Leu Gln Asp Tyr Lys Asn Thr Phe Pro Lys Trp Lys
                 275                 280                 285

 Pro Gly Ser Leu Ala Ser His Val Lys Asn Leu Asp Glu Asn Gly
                 290                 295                 300

 Leu Asp Leu Leu Ser Lys Met Leu Ile Tyr Asp Pro Ala Lys Arg
                 305                 310                 315

 Ile Ser Gly Lys Met Ala Leu Asn His Pro Tyr Phe Asn Asp Leu
                 320                 325                 330

 Asp Asn Gln Ile Lys Lys Met
                 335

<210> 831
<211> 1235
<212> DNA
<213> Homo sapien

<400> 831
 gggggggggg ggcacttggc ttcaaagctg gctcttggaa attgagcgga 50

 gagcgacgcg gttgttgtag ctgccgctgc ggccgccgcg gaataataag 100

 ccgggatcta ccatacccat tgactaacta tggaagatta taccaaaata 150

 gagaaaattg gagaaggtac ctatggagtt gtgtataagg gtagacacaa 200

 aactacaggt caagtggtag ccatgaaaaa aatcagacta gaaagtgaag 250

 aggaaggggt tcctagtact gcaattcggg aaatttctct attaaaggaa 300

 cttcgtcatc caaatatagt cagtcttcag gatgtgctta tgcaggattc 350

 caggttatat ctcatctttg agtttctttc catggatctg aagaaatact 400

 tggattctat ccctcctggt cagtacatgg attcttcact tgttaagagt 450

 tatttatacc aaatcctaca ggggattgtg ttttgtcact ctagaagagt 500

 tcttcacaga gacttaaaac ctcaaaatct cttgattgat gacaaaggaa 550

 caattaaact ggctgatttt ggccttgcca gagcttttgg aatacctatc 600

 agagtatata cacatgaggt agtaacactc tggtacagat ctccagaagt 650

 attgctgggg tcagctcgtt actcaactcc agttgacatt tggagtatag 700

 gcaccatatt tgctgaacta gcaactaaga aaccactttt ccatggggat 750

 tcagaaattg atcaactctt caggattttc agagctttgg gcactcccaa 800

 taatgaagtg tggccagaag tggaatcttt acaggactat aagaatacat 850

 ttcccaaatg gaaaccagga agcctagcat cccatgtcaa aaacttggat 900

 gaaaatggct tggatttgct ctcgaaaatg ttaatctatg atccagccaa 950

 acgaatttct ggcaaaatgg cactgaatca tccatatttt aatgatttgg 1000

 acaatcagat taagaagatg tagctttctg acaaaaagtt tccatatgtt 1050

 atgtcaacag atagttgtgt ttttattgtt aactcttgtc tatttttgtc 1100

 ttatatatat ttctttgtta tcaaacttca gctgtacttc gtcttctaat 1150

 ttcaaaaata taacttaaaa atgtaaatat tctatatgaa tttaaatata 1200

 attctgtaaa tgtgaaaaaa aaaaaaaaaa aaaaa 1235

<210> 832
<211> 297
<212> PRT
<213> Homo sapien

<400> 832
 Met Glu Asp Tyr Thr Lys Ile Glu Lys Ile Gly Glu Gly Thr Tyr
   1               5                  10                  15

 Gly Val Val Tyr Lys Gly Arg His Lys Thr Thr Gly Gln Val Val
                  20                  25                  30

 Ala Met Lys Lys Ile Arg Leu Glu Ser Glu Glu Glu Gly Val Pro
                  35                  40                  45

 Ser Thr Ala Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Arg His
                  50                  55                  60

 Pro Asn Ile Val Ser Leu Gln Asp Val Leu Met Gln Asp Ser Arg
                  65                  70                  75

 Leu Tyr Leu Ile Phe Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr
                  80                  85                  90

 Leu Asp Ser Ile Pro Pro Gly Gln Tyr Met Asp Ser Ser Leu Val
                  95                 100                 105

 Lys Ser Tyr Leu Tyr Gln Ile Leu Gln Gly Ile Val Phe Cys His
                 110                 115                 120

 Ser Arg Arg Val Leu His Arg Asp Leu Lys Pro Gln Asn Leu Leu
                 125                 130                 135

 Ile Asp Asp Lys Gly Thr Ile Lys Leu Ala Asp Phe Gly Leu Ala
                 140                 145                 150

 Arg Ala Phe Gly Ile Pro Ile Arg Val Tyr Thr His Glu Val Val
                 155                 160                 165

 Thr Leu Trp Tyr Arg Ser Pro Glu Val Leu Leu Gly Ser Ala Arg
                 170                 175                 180

 Tyr Ser Thr Pro Val Asp Ile Trp Ser Ile Gly Thr Ile Phe Ala
                 185                 190                 195

 Glu Leu Ala Thr Lys Lys Pro Leu Phe His Gly Asp Ser Glu Ile
                 200                 205                 210

 Asp Gln Leu Phe Arg Ile Phe Arg Ala Leu Gly Thr Pro Asn Asn
                 215                 220                 225

 Glu Val Trp Pro Glu Val Glu Ser Leu Gln Asp Tyr Lys Asn Thr
                 230                 235                 240

 Phe Pro Lys Trp Lys Pro Gly Ser Leu Ala Ser His Val Lys Asn
                 245                 250                 255

 Leu Asp Glu Asn Gly Leu Asp Leu Leu Ser Lys Met Leu Ile Tyr
                 260                 265                 270

 Asp Pro Ala Lys Arg Ile Ser Gly Lys Met Ala Leu Asn His Pro
                 275                 280                 285

 Tyr Phe Asn Asp Leu Asp Asn Gln Ile Lys Lys Met
                 290                 295

<210> 833
<211> 10660
<212> DNA
<213> Homo sapien

<400> 833
 ctactacagt ggcggacgta caggacctgt ttcactgcag ggggatccaa 50

 aacaagcccc gtggagcaac agccagagca acagcagctg caagacattg 100

 tttctctccc tctgcccccc cttccccacg caaccccaga tccatttaca 150

 ctttacagtt ttacctcaca aaaactacta caagcaccaa gctccctgat 200

 ggaaaggagc atcgtgcatc aagtcaccag ggtggtccat tcaagctgca 250

 gatttgtttg tcatccttgt acagcaatct cctcctccac tgccactaca 300

 gggaagtgca tcacatgtca gcatactgga gcatagtgaa agagtctatt 350

 ttgaagcttc aaacttagtg ctgctgcaga ccaggaacaa gagagaaaga 400

 gtggatttca gcctgcacgg atggtcttga aacacaaatg gtttttggtc 450

 taggcgtttt acactgagat tctccactgc caccctttct actcaagcaa 500

 aatcttcgtg aaaagatctg ctgcaaggaa ctgatagctt atggttctcc 550

 attgtgatga aagcacatgg tacagttttc caaagaaatt agaccatttt 600

 cttcgtgaga aagaaatcga cgtgctgttt tcatagggta tttctcactt 650

 ctctgtgaaa ggaagaaaga acacgcctga gcccaagagc cctcaggagc 700

 cctccagagc ctgtgggaag tctccatggt gaagtatagg ctgaggctac 750

 ctgtgaacag tacgcagtga atgttcatcc agagctgctg ttggcggatt 800

 gtacccacgg ggagatgatt cctcatgaag agcctggatc ccctacagaa 850

 atcaaatgtg actttccgtt tatcagacta aaatcagagc catccagaca 900

 gtgaaacagt caccgtggag gggggacggc gaaaaatgaa atccaaccaa 950

 gagcggagca acgaatgcct gcctcccaag aagcgcgaga tccccgccac 1000

 cagccggtcc tccgaggaga aggcccctac cctgcccagc gacaaccacc 1050

 gggtggaggg cacagcatgg ctcccgggca accctggtgg ccggggccac 1100

 gggggcggga ggcatgggcc ggcagggacc tcggtggagc ttggtttaca 1150

 acagggaata ggtttacaca aagcattgtc cacagggctg gactactccc 1200

 cgcccagcgc tcccaggtct gtccccgtgg ccaccacgct gcctgccgcg 1250

 tacgccaccc cgcagccagg gaccccggtg tcccccgtgc agtacgctca 1300

 cctgccgcac accttccagt tcattgggtc ctcccaatac agtggaacct 1350

 atgccagctt catcccatca cagctgatcc ccccaaccgc caaccccgtc 1400

 accagtgcag tggcctcggc cgcaggggcc accactccat cccagcgctc 1450

 ccagctggag gcctattcca ctctgctggc caacatgggc agtctgagcc 1500

 agacgccggg acacaaggct gagcagcagc agcagcagca gcagcagcag 1550

 cagcagcagc atcagcatca gcagcagcag cagcagcagc agcagcagca 1600

 gcagcagcag cagcacctca gcagggctcc ggggctcatc accccggggt 1650

 cccccccacc agcccagcag aaccagtacg tccacatttc cagttctccg 1700

 cagaacaccg gccgcaccgc ctctcctccg gccatccccg tccacctcca 1750

 cccccaccag acgatgatcc cacacacgct caccctgggg cccccctccc 1800

 aggtcgtcat gcaatacgcc gactccggca gccactttgt ccctcgggag 1850

 gccaccaaga aagctgagag cagccggctg cagcaggcca tccaggccaa 1900

 ggaggtcctg aacggtgaga tggagaagag ccggcggtac ggggccccgt 1950

 cctcagccga cctgggcctg ggcaaggcag gcggcaagtc ggttcctcac 2000

 ccgtacgagt ccaggcacgt ggtggtccac ccgagcccct cagactacag 2050

 cagtcgtgat ccttcggggg tccgggcctc tgtgatggtc ctgcccaaca 2100

 gcaacacgcc cgcagctgac ctggaggtgc aacaggccac tcatcgtgaa 2150

 gcctcccctt ctaccctcaa cgacaaaagt ggcctgcatt tagggaagcc 2200

 tggccaccgg tcctacgcgc tctcacccca cacggtcatt cagaccacac 2250

 acagtgcttc agagccactc ccggtgggac tgccagccac ggccttctac 2300

 gcagggactc aaccccctgt catcggctac ctgagcggcc agcagcaagc 2350

 aatcacctac gccggcagcc tgccccagca cctggtgatc cccggcacac 2400

 agcccctgct catcccggtc ggcagcactg acatggaagc gtcgggggca 2450

 gccccggcca tagtcacgtc atccccccag tttgctgcag tgcctcacac 2500

 gttcgtcacc accgcccttc ccaagagcga gaacttcaac cctgaggccc 2550

 tggtcaccca ggccgcctac ccagccatgg tgcaggccca gatccacctg 2600

 cctgtggtgc agtccgtggc ctccccggcg gcggctcccc ctacgctgcc 2650

 tccctacttc atgaaaggct ccatcatcca gttggccaac ggggagctaa 2700

 agaaggtgga agacttaaaa acagaagatt tcatccagag tgcagagata 2750

 agcaacgacc tgaagatcga ctccagcacc gtagagagga ttgaagacag 2800

 ccatagcccg ggcgtggccg tgatacagtt cgccgtcggg gagcaccgag 2850

 cccaggtcag cgttgaagtt ttggtagagt atcctttttt tgtgtttgga 2900

 cagggctggt catcctgctg tccggagaga accagccagc tctttgattt 2950

 gccgtgttcc aaactctcag ttggggatgt ctgcatctcg cttaccctca 3000

 agaacctgaa gaacggctct gttaaaaagg gccagcccgt ggatcccgcc 3050

 agcgtcctgc tgaagcactc aaaggccgac ggcctggcgg gcagcagaca 3100

 caggtatgcc gagcaggaaa acggaatcaa ccaggggagt gcccagatgc 3150

 tctctgagaa tggcgaactg aagtttccag agaaaatggg attgcctgca 3200

 gcgcccttcc tcaccaaaat agaacccagc aagcccgcgg caacgaggaa 3250

 gaggaggtgg tcggcgccag agagccgcaa actggagaag tcagaagacg 3300

 aaccaccttt gactcttcct aagccttctc taattcctca ggaggttaag 3350

 atttgcattg aaggccggtc taatgtaggc aagtagaggc agcgtggggg 3400

 aaaggaaacg tggctctccc ttatcatttg tatccagatt actgtactgt 3450

 aggctaaaat aacacagtat ttacatgtta tcttcttaat tttaggtttc 3500

 tgttctaacc ttgtcattag agttacagca ggtgtgtcgc aggagactgg 3550

 tgcatatgct ttttccacga gtgtctgtca gtgagcgggc gggaggaagg 3600

 gcacagcagg agcggtcagg gctccaggca tccccgggga agaaaggaac 3650

 ggggcttcac agtgcctgcc ttctctagcg gcacagaagc agccgggggc 3700

 gctgactccc gctagtgtca ggagaaaagt cccgtgggaa gagtcctgca 3750

 ggggtgcagg gttgcacgca tgtgggggtg cacaggcgct gtggcggcga 3800

 gtgagggtct ctttttctct gcctccctct gcctcactct cttgctatcg 3850

 gcatgggccg ggggggttca gagcagtgtc ctcctggggt tcccacgtgc 3900

 aaaatcaaca tcaggaaccc agcttcaggg catcgcggag acgcgtcaga 3950

 tggcagattt ggaaagttaa ccatttaaaa gaacattttt ctctccaaca 4000

 tattttacaa taaaagcaac ttttaattgt atagatatat atttccccct 4050

 atggggcctg actgcactga tatatatttt ttttaaagag caactgccac 4100

 atgcgggatt tcatttctgc tttttactag tgcagcgatg tcaccagggt 4150

 gttgtggtgg acagggaagc ccctgctgtc atggccccac atggggtaag 4200

 gggggttggg ggtgggggag agggagagag cgaacaccca cgctggtttc 4250

 tgtgcagtgt taggaaaacc aatcaggtta ttgcattgac ttcactccca 4300

 agaggtagat gcaaactgcc cttcagtgag agcaacagaa gctcttcacg 4350

 ttgagtttgc gaaatctttt tgtctttgaa ctctagtact gtttatagtt 4400

 catgactatg gacaactcgg gtgccacttt tttttttttc agattccagt 4450

 gtgacatgag gaattagatt ttgaagatga gcatatatta ctatctttaa 4500

 gcatttaaaa atactgttca cactttatta ccaagcatct tggtctctca 4550

 ttcaacaagt actgtatctc actttaaact ctttggggaa aaaacaaaaa 4600

 caaaaaaaac taagttgctt tctttttttc aacactgtaa ctacatttca 4650

 gctctgcaga attgctgaag agcaagatat tgaaagtttc aatgtggttt 4700

 aaagggatga atgtgaatta tgaactagta tgtgacaata aatgaccacc 4750

 aagtactacc tgacgggagg cacttttcac tttgatgtct gagaatcagt 4800

 tcaaggcata tgcagagttg gcagagaaac tgagagaaaa gggatggaga 4850

 agagaatact catttttgtc cagtgttttt ctttttaaga tgaactttta 4900

 aagaaccttg cgatttgcac atattgagtt tataacttgt gtgatattcc 4950

 tgcagttttt atccaataac attgtgggaa aggtttgggg gactgaacga 5000

 gcataaataa atgtagcaaa atttctttct aacctgccta aactctaggc 5050

 cattttataa ggttatgttc ctttgaaaat tcattttggt ctttttacca 5100

 catctgtcac aaaaagccag gtcttagcgg gctcttagaa actctgagaa 5150

 ttttcttcag attcattgag agagttttcc ataaagacat ttatatatgt 5200

 gagcaagatt ttttttaaac aattacttta ttattgttgt tattaatgtt 5250

 attttcagaa tggctttttt tttctattca aaatcaaatc gagatttaat 5300

 gtttggtaca aacccagaaa gggtatttca tagtttttaa acctttcatt 5350

 cccagagatc cgaaatatca tttgtgggtt ttgaatgcat ctttaaagtg 5400

 ctttaaaaaa aagttttata agtagggaga aatttttaaa tattcttact 5450

 tggatggctg caactaaact gaacaaatac ctgacttttc ttttacccca 5500

 ttgaaaatag tactttcttc gtttcacaaa ttaaaaaaaa aatctggtat 5550

 caacccacat tttggctgtc tagtattcat ttacatttag ggttcaccag 5600

 gactaatgat ttttataaac cgttttctgg ggtgtaccaa aaacatttga 5650

 ataggtttag aatagctaga atagttcctt gactttcctc gaatttcatt 5700

 accctctcag catgcttgca gagagctggg tgggctcatt cttgcagtca 5750

 tactgcttat ttagtgctgt attttttaaa cgtttctgtt cagagaactt 5800

 gcttaatctt ccatatattc tgctcagggc acttgcaatt attaggtttt 5850

 gtttttcttt ttgtttttta gcctttgatg gtaagaggaa tacgggctgc 5900

 cacatagact ttgttctcat taatatcact atttacaact catgtggact 5950

 cagaaaaaca cacaccacct tttggcttac ttcgagtatt gaattgactg 6000

 gatccactaa accaacacta agatgggaaa acacacatgg tttggagcaa 6050

 taggaacatc atcataattt ttgtggttct atttcaggta taggaattat 6100

 aaaataattg gttctttcta aacacttgtc ccatttcatt ctcttgcttt 6150

 tttagcatgt gcaatacttt ctgtgccaat agagtctgac cagtgtgcta 6200

 tatagttaaa gctcattccc ttttggcttt ttccttgttt ggttgatctt 6250

 ccccattctg gccagagcag ggctggaggg aaggagccag gagggagaga 6300

 gcctcccacc tttcccctgc tgcggatgct gagtgctggg gcggggagcc 6350

 ttcaggagcc ccgtgcgtct gccgccacgt tgcagaaaga gccagccaag 6400

 gagacccggg ggaggaaccg cagtgtcccc tgtcaccaca cggaatagtg 6450

 aatgtggagt gtggagagga aggaggcaga ttcatttcta agacgcactc 6500

 tggagccatg tagcctggag tcaacccatt ttccacggtc ttttctgcaa 6550

 gtgggcaggc ccctcctcgg ggtctgtgtc cttgagactt ggagccctgc 6600

 ctctgagcct ggacgggaag tgtggcctgt tgtgtgtgtg cgttctgagc 6650

 gtgttggcca gtggctgtgg aggggaccac ctgccaccca cggtcaccac 6700

 tcccttgtgg cagctttctc ttcaaatagg aagaacgcac agagggcagg 6750

 agcctcctgt ttgcagacgt tggcgggccc cgaggctccc agagcagcct 6800

 ctgtcaccgc ttctgtgtag caaacattaa cgatgacagg ggtagaaatt 6850

 cttcggtgcc gttcagctta caaggatcag ccatgtgcct ctgtactatg 6900

 tccactttgc aatatttacc gacagccgtc ttttgttctt tctttcctgt 6950

 tttccatttt taaactagta acagcaggcc ttttgcgttt acaatggaac 7000

 acaatcacca agaaattagt cagggcgaaa agaaaaaaat aatactatta 7050

 ataagaaacc aacaaacaag aacctctctt tctagggatt tctaaatata 7100

 taaaatgact gttccttaga atgtttaact taagaattat ttcagtttgt 7150

 ctgggccaca ctggggcaga ggggggaggg agggatacag agatggatgc 7200

 cacttacctc agatctttta aagtggaaat ccaaattgaa ttttcatttg 7250

 gactttcagg ataattttct atgttggtca acttttcgtt ttccctaact 7300

 cacccagttt agtttgggat gatttgattt ctgttgttgt tgatcccatt 7350

 tctaacttgg aattgtgagc ctctatgttt tctgttaggt gagtgtgttg 7400

 ggttttttcc ccccaccagg aagtggcagc atccctcctt ctcccctaaa 7450

 gggactctgc ggaacctttc acacctcttt ctcagggacg gggcaggtgt 7500

 gtgtgtggta cactgacgtg tccagaagca gcactttgac tgctctggag 7550

 tagggttgta caatttcaag gaatgtttgg atttcctgca tcttgtggat 7600

 tactccttag ataccgcata gattgcaata taatgctgca tgttcaagat 7650

 gaacagtagc tcctagtaat cataaaatcc actctttgca cagtttgatc 7700

 tttactgaaa tatgttgcca aaatttattt ttgttgttgt agctctggat 7750

 tttgttttgt tttgtttttt aaggaaacga ttgacaatac cctttaacat 7800

 ctgtgactac taaggaaacc tatttctttc atagagagaa aaatctccaa 7850

 tgcttttgaa gacactaata ccgtgctatt tcagatatgg gtgaggaagc 7900

 agagctctcg gtaccgaagg ccgggcttct tgagctgtgt tggttgtcat 7950

 ggctactgtt tcatgaacca caagcagctc aacagactgg tctgttgcct 8000

 tctgaaaccc tttgcacttc aatttgcacc aggtgaaaac agggccagca 8050

 gactccatgg cccaattcgg tttcttcggt ggtgatgtga aaggagagaa 8100

 ttacactttt ttttttttta agtggcgtgg aggcctttgc ttccacattt 8150

 gtttttaacc cagaatttct gaaatagaga atttaagaac acatcaagta 8200

 ataaatatac agagaatata cttttttata aagcacatgc atctgctatt 8250

 gtgttgggtt ggtttcctct cttttccacg gacagtgttg tgtttctggc 8300

 atagggaaac tccaaacaac ttgcacacct ctactccgga gctgagattt 8350

 cttttacata gatgacctcg cttcaaatac gttaccttac tgatgatagg 8400

 atcttttctt gtagcactat accttgtggg aatttttttt taaatgtaca 8450

 cctgatttga gaagctgaag aaaacaaaat tttgaagcac tcactttgag 8500

 gagtacaggt aatgttttaa aaaattgcac aaaagaaaaa tgaatgtcga 8550

 aatgattcat tcagtgtttg aaagatatgg ctctgttgaa acaatgagtt 8600

 tcatactttg tttgtaaaaa aaaaaagcag agaagggttg aaagttacat 8650

 gtttttttgt atatagaaat ttgtcatgtc taaatgatca gatttgtatg 8700

 gttatggcct ggaagaatta ctacgtaaaa ggctcttaaa ctatacctat 8750

 gcttattgtt atttttgtta catatagccc tcgtctgagg gaggggaact 8800

 cggtattctg cgatttgaga atactgttca ttcctatgct gaaagtactt 8850

 ctctgagctc ccttcttagt ctaaactctt aagccattgc aacttctttt 8900

 tcttcagaga tgatgtttga cattttcagc acttcctgtt cctataaacc 8950

 caaagaatat aatcttgaac acgaagtgtt tgtaacaagg gatccaggct 9000

 accaatcaaa caggactcat tatggggaca aaaaaaaaaa aaattatttc 9050

 accttctttc cccccacacc tcatttaaat ggggggagta aaaacatgat 9100

 ttcaatgtaa atgcctcatt ttattttagt tttattttga tttttattta 9150

 atataaagag gccagaataa atacggagca tcttctcaga atagtattcc 9200

 tgtccaaaaa tcaagccgga cagtggaaac tggacagctg tggggatatt 9250

 aagcaccccc acttacaatt cttaaattca gaatctcgtc ccctcccttc 9300

 tcgttgaagg caactgttct ggtagctaac tttctcctgt gtaatggcgg 9350

 gagggaacac cggcttcagt ttttcatgtc cccatgactt gcatacaaat 9400

 ggttcaactg tattaaaatt aagtgcattt ggccaatagg tagtatctat 9450

 acaataacaa caatctctaa gaatttccat aacttttctt atctgaaagg 9500

 actcaagtct tccactgcag atacattgga ggcttcaccc acgttttctt 9550

 tccctttagt ttgtttgctg tctggatggc caatgagcct gtctcctttt 9600

 ctgtggccaa tctgaaggcc ttcgttggaa gtgttgttca cagtaatcct 9650

 taccaagata acatactgtc ctccagaata ccaagtatta ggtgacacta 9700

 gctcaagctg ttgtcttcag agcagttacc aagaagctcg gtgcacaggt 9750

 tttctctggt tcttacagga accacctact ctttcagttt tctggcccag 9800

 gagtggggta aatcctttag ttagtgcatt tgaacttggt acctgtgcat 9850

 tcagttctgt gaatactgcc ctttttggcg gggtttcctc atctccccag 9900

 cctgaactgc tcaactctaa acccaaatta gtgtcagccg aaaggaggtt 9950

 tcaagatagt cctgtcagta tttgtggtga ccttcagatt agacagtctt 10000

 catttccagc cagtggagtc ctggctccag agccatctct gagactccgt 10050

 actactggat gttttaatat cagatcatta cccaccatat gcctcccaca 10100

 ggccaaggga aaacagacac cagaacttgg gttgagggca ctaccagact 10150

 gacatggcca gtacagagga gaactaggga aggaatgatg ttttgcacct 10200

 tattgaaaag aaaattttaa gtgcatacat aatagttaag agcttttatt 10250

 gtgacaggag aacttttttc catatgcgtg catactctct gtaattccag 10300

 tgtaaaatat tgtacttgca ctagcttttt taaacaaata ttaaaaaatg 10350

 gaagaattca tattctattt tctaatcgtg gtgtgtctat ttgtaggata 10400

 cactcgagtc tgtttattga attttatggt ccctttcttt gatggtgctt 10450

 gcaggttttc taggtagaaa ttatttcatt attataataa aacaatgttt 10500

 gattcaaaat ttgaacaaaa ttgttttaaa taaattgtct gtataccagt 10550

 acaagtttat tgtttcagta tactcgtact aataaaataa cagtgccaat 10600

 tgcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 10650

 aaaaaaaaaa 10660

<210> 834
<211> 816
<212> PRT
<213> Homo sapien

<400> 834
 Met Lys Ser Asn Gln Glu Arg Ser Asn Glu Cys Leu Pro Pro Lys
   1               5                  10                  15

 Lys Arg Glu Ile Pro Ala Thr Ser Arg Ser Ser Glu Glu Lys Ala
                  20                  25                  30

 Pro Thr Leu Pro Ser Asp Asn His Arg Val Glu Gly Thr Ala Trp
                  35                  40                  45

 Leu Pro Gly Asn Pro Gly Gly Arg Gly His Gly Gly Gly Arg His
                  50                  55                  60

 Gly Pro Ala Gly Thr Ser Val Glu Leu Gly Leu Gln Gln Gly Ile
                  65                  70                  75

 Gly Leu His Lys Ala Leu Ser Thr Gly Leu Asp Tyr Ser Pro Pro
                  80                  85                  90

 Ser Ala Pro Arg Ser Val Pro Val Ala Thr Thr Leu Pro Ala Ala
                  95                 100                 105

 Tyr Ala Thr Pro Gln Pro Gly Thr Pro Val Ser Pro Val Gln Tyr
                 110                 115                 120

 Ala His Leu Pro His Thr Phe Gln Phe Ile Gly Ser Ser Gln Tyr
                 125                 130                 135

 Ser Gly Thr Tyr Ala Ser Phe Ile Pro Ser Gln Leu Ile Pro Pro
                 140                 145                 150

 Thr Ala Asn Pro Val Thr Ser Ala Val Ala Ser Ala Ala Gly Ala
                 155                 160                 165

 Thr Thr Pro Ser Gln Arg Ser Gln Leu Glu Ala Tyr Ser Thr Leu
                 170                 175                 180

 Leu Ala Asn Met Gly Ser Leu Ser Gln Thr Pro Gly His Lys Ala
                 185                 190                 195

 Glu Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln His Gln
                 200                 205                 210

 His Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                 215                 220                 225

 Gln His Leu Ser Arg Ala Pro Gly Leu Ile Thr Pro Gly Ser Pro
                 230                 235                 240

 Pro Pro Ala Gln Gln Asn Gln Tyr Val His Ile Ser Ser Ser Pro
                 245                 250                 255

 Gln Asn Thr Gly Arg Thr Ala Ser Pro Pro Ala Ile Pro Val His
                 260                 265                 270

 Leu His Pro His Gln Thr Met Ile Pro His Thr Leu Thr Leu Gly
                 275                 280                 285

 Pro Pro Ser Gln Val Val Met Gln Tyr Ala Asp Ser Gly Ser His
                 290                 295                 300

 Phe Val Pro Arg Glu Ala Thr Lys Lys Ala Glu Ser Ser Arg Leu
                 305                 310                 315

 Gln Gln Ala Ile Gln Ala Lys Glu Val Leu Asn Gly Glu Met Glu
                 320                 325                 330

 Lys Ser Arg Arg Tyr Gly Ala Pro Ser Ser Ala Asp Leu Gly Leu
                 335                 340                 345

 Gly Lys Ala Gly Gly Lys Ser Val Pro His Pro Tyr Glu Ser Arg
                 350                 355                 360

 His Val Val Val His Pro Ser Pro Ser Asp Tyr Ser Ser Arg Asp
                 365                 370                 375

 Pro Ser Gly Val Arg Ala Ser Val Met Val Leu Pro Asn Ser Asn
                 380                 385                 390

 Thr Pro Ala Ala Asp Leu Glu Val Gln Gln Ala Thr His Arg Glu
                 395                 400                 405

 Ala Ser Pro Ser Thr Leu Asn Asp Lys Ser Gly Leu His Leu Gly
                 410                 415                 420

 Lys Pro Gly His Arg Ser Tyr Ala Leu Ser Pro His Thr Val Ile
                 425                 430                 435

 Gln Thr Thr His Ser Ala Ser Glu Pro Leu Pro Val Gly Leu Pro
                 440                 445                 450

 Ala Thr Ala Phe Tyr Ala Gly Thr Gln Pro Pro Val Ile Gly Tyr
                 455                 460                 465

 Leu Ser Gly Gln Gln Gln Ala Ile Thr Tyr Ala Gly Ser Leu Pro
                 470                 475                 480

 Gln His Leu Val Ile Pro Gly Thr Gln Pro Leu Leu Ile Pro Val
                 485                 490                 495

 Gly Ser Thr Asp Met Glu Ala Ser Gly Ala Ala Pro Ala Ile Val
                 500                 505                 510

 Thr Ser Ser Pro Gln Phe Ala Ala Val Pro His Thr Phe Val Thr
                 515                 520                 525

 Thr Ala Leu Pro Lys Ser Glu Asn Phe Asn Pro Glu Ala Leu Val
                 530                 535                 540

 Thr Gln Ala Ala Tyr Pro Ala Met Val Gln Ala Gln Ile His Leu
                 545                 550                 555

 Pro Val Val Gln Ser Val Ala Ser Pro Ala Ala Ala Pro Pro Thr
                 560                 565                 570

 Leu Pro Pro Tyr Phe Met Lys Gly Ser Ile Ile Gln Leu Ala Asn
                 575                 580                 585

 Gly Glu Leu Lys Lys Val Glu Asp Leu Lys Thr Glu Asp Phe Ile
                 590                 595                 600

 Gln Ser Ala Glu Ile Ser Asn Asp Leu Lys Ile Asp Ser Ser Thr
                 605                 610                 615

 Val Glu Arg Ile Glu Asp Ser His Ser Pro Gly Val Ala Val Ile
                 620                 625                 630

 Gln Phe Ala Val Gly Glu His Arg Ala Gln Val Ser Val Glu Val
                 635                 640                 645

 Leu Val Glu Tyr Pro Phe Phe Val Phe Gly Gln Gly Trp Ser Ser
                 650                 655                 660

 Cys Cys Pro Glu Arg Thr Ser Gln Leu Phe Asp Leu Pro Cys Ser
                 665                 670                 675

 Lys Leu Ser Val Gly Asp Val Cys Ile Ser Leu Thr Leu Lys Asn
                 680                 685                 690

 Leu Lys Asn Gly Ser Val Lys Lys Gly Gln Pro Val Asp Pro Ala
                 695                 700                 705

 Ser Val Leu Leu Lys His Ser Lys Ala Asp Gly Leu Ala Gly Ser
                 710                 715                 720

 Arg His Arg Tyr Ala Glu Gln Glu Asn Gly Ile Asn Gln Gly Ser
                 725                 730                 735

 Ala Gln Met Leu Ser Glu Asn Gly Glu Leu Lys Phe Pro Glu Lys
                 740                 745                 750

 Met Gly Leu Pro Ala Ala Pro Phe Leu Thr Lys Ile Glu Pro Ser
                 755                 760                 765

 Lys Pro Ala Ala Thr Arg Lys Arg Arg Trp Ser Ala Pro Glu Ser
                 770                 775                 780

 Arg Lys Leu Glu Lys Ser Glu Asp Glu Pro Pro Leu Thr Leu Pro
                 785                 790                 795

 Lys Pro Ser Leu Ile Pro Gln Glu Val Lys Ile Cys Ile Glu Gly
                 800                 805                 810

 Arg Ser Asn Val Gly Lys
                 815

<210> 835
<211> 10660
<212> DNA
<213> Homo sapien

<400> 835
 ctactacagt ggcggacgta caggacctgt ttcactgcag ggggatccaa 50

 aacaagcccc gtggagcaac agccagagca acagcagctg caagacattg 100

 tttctctccc tctgcccccc cttccccacg caaccccaga tccatttaca 150

 ctttacagtt ttacctcaca aaaactacta caagcaccaa gctccctgat 200

 ggaaaggagc atcgtgcatc aagtcaccag ggtggtccat tcaagctgca 250

 gatttgtttg tcatccttgt acagcaatct cctcctccac tgccactaca 300

 gggaagtgca tcacatgtca gcatactgga gcatagtgaa agagtctatt 350

 ttgaagcttc aaacttagtg ctgctgcaga ccaggaacaa gagagaaaga 400

 gtggatttca gcctgcacgg atggtcttga aacacaaatg gtttttggtc 450

 taggcgtttt acactgagat tctccactgc caccctttct actcaagcaa 500

 aatcttcgtg aaaagatctg ctgcaaggaa ctgatagctt atggttctcc 550

 attgtgatga aagcacatgg tacagttttc caaagaaatt agaccatttt 600

 cttcgtgaga aagaaatcga cgtgctgttt tcatagggta tttctcactt 650

 ctctgtgaaa ggaagaaaga acacgcctga gcccaagagc cctcaggagc 700

 cctccagagc ctgtgggaag tctccatggt gaagtatagg ctgaggctac 750

 ctgtgaacag tacgcagtga atgttcatcc agagctgctg ttggcggatt 800

 gtacccacgg ggagatgatt cctcatgaag agcctggatc ccctacagaa 850

 atcaaatgtg actttccgtt tatcagacta aaatcagagc catccagaca 900

 gtgaaacagt caccgtggag gggggacggc gaaaaatgaa atccaaccaa 950

 gagcggagca acgaatgcct gcctcccaag aagcgcgaga tccccgccac 1000

 cagccggtcc tccgaggaga aggcccctac cctgcccagc gacaaccacc 1050

 gggtggaggg cacagcatgg ctcccgggca accctggtgg ccggggccac 1100

 gggggcggga ggcatgggcc ggcagggacc tcggtggagc ttggtttaca 1150

 acagggaata ggtttacaca aagcattgtc cacagggctg gactactccc 1200

 cgcccagcgc tcccaggtct gtccccgtgg ccaccacgct gcctgccgcg 1250

 tacgccaccc cgcagccagg gaccccggtg tcccccgtgc agtacgctca 1300

 cctgccgcac accttccagt tcattgggtc ctcccaatac agtggaacct 1350

 atgccagctt catcccatca cagctgatcc ccccaaccgc caaccccgtc 1400

 accagtgcag tggcctcggc cgcaggggcc accactccat cccagcgctc 1450

 ccagctggag gcctattcca ctctgctggc caacatgggc agtctgagcc 1500

 agacgccggg acacaaggct gagcagcagc agcagcagca gcagcagcag 1550

 cagcagcagc atcagcatca gcagcagcag cagcagcagc agcagcagca 1600

 gcagcagcag cagcacctca gcagggctcc ggggctcatc accccggggt 1650

 cccccccacc agcccagcag aaccagtacg tccacatttc cagttctccg 1700

 cagaacaccg gccgcaccgc ctctcctccg gccatccccg tccacctcca 1750

 cccccaccag acgatgatcc cacacacgct caccctgggg cccccctccc 1800

 aggtcgtcat gcaatacgcc gactccggca gccactttgt ccctcgggag 1850

 gccaccaaga aagctgagag cagccggctg cagcaggcca tccaggccaa 1900

 ggaggtcctg aacggtgaga tggagaagag ccggcggtac ggggccccgt 1950

 cctcagccga cctgggcctg ggcaaggcag gcggcaagtc ggttcctcac 2000

 ccgtacgagt ccaggcacgt ggtggtccac ccgagcccct cagactacag 2050

 cagtcgtgat ccttcggggg tccgggcctc tgtgatggtc ctgcccaaca 2100

 gcaacacgcc cgcagctgac ctggaggtgc aacaggccac tcatcgtgaa 2150

 gcctcccctt ctaccctcaa cgacaaaagt ggcctgcatt tagggaagcc 2200

 tggccaccgg tcctacgcgc tctcacccca cacggtcatt cagaccacac 2250

 acagtgcttc agagccactc ccggtgggac tgccagccac ggccttctac 2300

 gcagggactc aaccccctgt catcggctac ctgagcggcc agcagcaagc 2350

 aatcacctac gccggcagcc tgccccagca cctggtgatc cccggcacac 2400

 agcccctgct catcccggtc ggcagcactg acatggaagc gtcgggggca 2450

 gccccggcca tagtcacgtc atccccccag tttgctgcag tgcctcacac 2500

 gttcgtcacc accgcccttc ccaagagcga gaacttcaac cctgaggccc 2550

 tggtcaccca ggccgcctac ccagccatgg tgcaggccca gatccacctg 2600

 cctgtggtgc agtccgtggc ctccccggcg gcggctcccc ctacgctgcc 2650

 tccctacttc atgaaaggct ccatcatcca gttggccaac ggggagctaa 2700

 agaaggtgga agacttaaaa acagaagatt tcatccagag tgcagagata 2750

 agcaacgacc tgaagatcga ctccagcacc gtagagagga ttgaagacag 2800

 ccatagcccg ggcgtggccg tgatacagtt cgccgtcggg gagcaccgag 2850

 cccaggtcag cgttgaagtt ttggtagagt atcctttttt tgtgtttgga 2900

 cagggctggt catcctgctg tccggagaga accagccagc tctttgattt 2950

 gccgtgttcc aaactctcag ttggggatgt ctgcatctcg cttaccctca 3000

 agaacctgaa gaacggctct gttaaaaagg gccagcccgt ggatcccgcc 3050

 agcgtcctgc tgaagcactc aaaggccgac ggcctggcgg gcagcagaca 3100

 caggtatgcc gagcaggaaa acggaatcaa ccaggggagt gcccagatgc 3150

 tctctgagaa tggcgaactg aagtttccag agaaaatggg attgcctgca 3200

 gcgcccttcc tcaccaaaat agaacccagc aagcccgcgg caacgaggaa 3250

 gaggaggtgg tcggcgccag agagccgcaa actggagaag tcagaagacg 3300

 aaccaccttt gactcttcct aagccttctc taattcctca ggaggttaag 3350

 atttgcattg aaggccggtc taatgtaggc aagtagaggc agcgtggggg 3400

 aaaggaaacg tggctctccc ttatcatttg tatccagatt actgtactgt 3450

 aggctaaaat aacacagtat ttacatgtta tcttcttaat tttaggtttc 3500

 tgttctaacc ttgtcattag agttacagca ggtgtgtcgc aggagactgg 3550

 tgcatatgct ttttccacga gtgtctgtca gtgagcgggc gggaggaagg 3600

 gcacagcagg agcggtcagg gctccaggca tccccgggga agaaaggaac 3650

 ggggcttcac agtgcctgcc ttctctagcg gcacagaagc agccgggggc 3700

 gctgactccc gctagtgtca ggagaaaagt cccgtgggaa gagtcctgca 3750

 ggggtgcagg gttgcacgca tgtgggggtg cacaggcgct gtggcggcga 3800

 gtgagggtct ctttttctct gcctccctct gcctcactct cttgctatcg 3850

 gcatgggccg ggggggttca gagcagtgtc ctcctggggt tcccacgtgc 3900

 aaaatcaaca tcaggaaccc agcttcaggg catcgcggag acgcgtcaga 3950

 tggcagattt ggaaagttaa ccatttaaaa gaacattttt ctctccaaca 4000

 tattttacaa taaaagcaac ttttaattgt atagatatat atttccccct 4050

 atggggcctg actgcactga tatatatttt ttttaaagag caactgccac 4100

 atgcgggatt tcatttctgc tttttactag tgcagcgatg tcaccagggt 4150

 gttgtggtgg acagggaagc ccctgctgtc atggccccac atggggtaag 4200

 gggggttggg ggtgggggag agggagagag cgaacaccca cgctggtttc 4250

 tgtgcagtgt taggaaaacc aatcaggtta ttgcattgac ttcactccca 4300

 agaggtagat gcaaactgcc cttcagtgag agcaacagaa gctcttcacg 4350

 ttgagtttgc gaaatctttt tgtctttgaa ctctagtact gtttatagtt 4400

 catgactatg gacaactcgg gtgccacttt tttttttttc agattccagt 4450

 gtgacatgag gaattagatt ttgaagatga gcatatatta ctatctttaa 4500

 gcatttaaaa atactgttca cactttatta ccaagcatct tggtctctca 4550

 ttcaacaagt actgtatctc actttaaact ctttggggaa aaaacaaaaa 4600

 caaaaaaaac taagttgctt tctttttttc aacactgtaa ctacatttca 4650

 gctctgcaga attgctgaag agcaagatat tgaaagtttc aatgtggttt 4700

 aaagggatga atgtgaatta tgaactagta tgtgacaata aatgaccacc 4750

 aagtactacc tgacgggagg cacttttcac tttgatgtct gagaatcagt 4800

 tcaaggcata tgcagagttg gcagagaaac tgagagaaaa gggatggaga 4850

 agagaatact catttttgtc cagtgttttt ctttttaaga tgaactttta 4900

 aagaaccttg cgatttgcac atattgagtt tataacttgt gtgatattcc 4950

 tgcagttttt atccaataac attgtgggaa aggtttgggg gactgaacga 5000

 gcataaataa atgtagcaaa atttctttct aacctgccta aactctaggc 5050

 cattttataa ggttatgttc ctttgaaaat tcattttggt ctttttacca 5100

 catctgtcac aaaaagccag gtcttagcgg gctcttagaa actctgagaa 5150

 ttttcttcag attcattgag agagttttcc ataaagacat ttatatatgt 5200

 gagcaagatt ttttttaaac aattacttta ttattgttgt tattaatgtt 5250

 attttcagaa tggctttttt tttctattca aaatcaaatc gagatttaat 5300

 gtttggtaca aacccagaaa gggtatttca tagtttttaa acctttcatt 5350

 cccagagatc cgaaatatca tttgtgggtt ttgaatgcat ctttaaagtg 5400

 ctttaaaaaa aagttttata agtagggaga aatttttaaa tattcttact 5450

 tggatggctg caactaaact gaacaaatac ctgacttttc ttttacccca 5500

 ttgaaaatag tactttcttc gtttcacaaa ttaaaaaaaa aatctggtat 5550

 caacccacat tttggctgtc tagtattcat ttacatttag ggttcaccag 5600

 gactaatgat ttttataaac cgttttctgg ggtgtaccaa aaacatttga 5650

 ataggtttag aatagctaga atagttcctt gactttcctc gaatttcatt 5700

 accctctcag catgcttgca gagagctggg tgggctcatt cttgcagtca 5750

 tactgcttat ttagtgctgt attttttaaa cgtttctgtt cagagaactt 5800

 gcttaatctt ccatatattc tgctcagggc acttgcaatt attaggtttt 5850

 gtttttcttt ttgtttttta gcctttgatg gtaagaggaa tacgggctgc 5900

 cacatagact ttgttctcat taatatcact atttacaact catgtggact 5950

 cagaaaaaca cacaccacct tttggcttac ttcgagtatt gaattgactg 6000

 gatccactaa accaacacta agatgggaaa acacacatgg tttggagcaa 6050

 taggaacatc atcataattt ttgtggttct atttcaggta taggaattat 6100

 aaaataattg gttctttcta aacacttgtc ccatttcatt ctcttgcttt 6150

 tttagcatgt gcaatacttt ctgtgccaat agagtctgac cagtgtgcta 6200

 tatagttaaa gctcattccc ttttggcttt ttccttgttt ggttgatctt 6250

 ccccattctg gccagagcag ggctggaggg aaggagccag gagggagaga 6300

 gcctcccacc tttcccctgc tgcggatgct gagtgctggg gcggggagcc 6350

 ttcaggagcc ccgtgcgtct gccgccacgt tgcagaaaga gccagccaag 6400

 gagacccggg ggaggaaccg cagtgtcccc tgtcaccaca cggaatagtg 6450

 aatgtggagt gtggagagga aggaggcaga ttcatttcta agacgcactc 6500

 tggagccatg tagcctggag tcaacccatt ttccacggtc ttttctgcaa 6550

 gtgggcaggc ccctcctcgg ggtctgtgtc cttgagactt ggagccctgc 6600

 ctctgagcct ggacgggaag tgtggcctgt tgtgtgtgtg cgttctgagc 6650

 gtgttggcca gtggctgtgg aggggaccac ctgccaccca cggtcaccac 6700

 tcccttgtgg cagctttctc ttcaaatagg aagaacgcac agagggcagg 6750

 agcctcctgt ttgcagacgt tggcgggccc cgaggctccc agagcagcct 6800

 ctgtcaccgc ttctgtgtag caaacattaa cgatgacagg ggtagaaatt 6850

 cttcggtgcc gttcagctta caaggatcag ccatgtgcct ctgtactatg 6900

 tccactttgc aatatttacc gacagccgtc ttttgttctt tctttcctgt 6950

 tttccatttt taaactagta acagcaggcc ttttgcgttt acaatggaac 7000

 acaatcacca agaaattagt cagggcgaaa agaaaaaaat aatactatta 7050

 ataagaaacc aacaaacaag aacctctctt tctagggatt tctaaatata 7100

 taaaatgact gttccttaga atgtttaact taagaattat ttcagtttgt 7150

 ctgggccaca ctggggcaga ggggggaggg agggatacag agatggatgc 7200

 cacttacctc agatctttta aagtggaaat ccaaattgaa ttttcatttg 7250

 gactttcagg ataattttct atgttggtca acttttcgtt ttccctaact 7300

 cacccagttt agtttgggat gatttgattt ctgttgttgt tgatcccatt 7350

 tctaacttgg aattgtgagc ctctatgttt tctgttaggt gagtgtgttg 7400

 ggttttttcc ccccaccagg aagtggcagc atccctcctt ctcccctaaa 7450

 gggactctgc ggaacctttc acacctcttt ctcagggacg gggcaggtgt 7500

 gtgtgtggta cactgacgtg tccagaagca gcactttgac tgctctggag 7550

 tagggttgta caatttcaag gaatgtttgg atttcctgca tcttgtggat 7600

 tactccttag ataccgcata gattgcaata taatgctgca tgttcaagat 7650

 gaacagtagc tcctagtaat cataaaatcc actctttgca cagtttgatc 7700

 tttactgaaa tatgttgcca aaatttattt ttgttgttgt agctctggat 7750

 tttgttttgt tttgtttttt aaggaaacga ttgacaatac cctttaacat 7800

 ctgtgactac taaggaaacc tatttctttc atagagagaa aaatctccaa 7850

 tgcttttgaa gacactaata ccgtgctatt tcagatatgg gtgaggaagc 7900

 agagctctcg gtaccgaagg ccgggcttct tgagctgtgt tggttgtcat 7950

 ggctactgtt tcatgaacca caagcagctc aacagactgg tctgttgcct 8000

 tctgaaaccc tttgcacttc aatttgcacc aggtgaaaac agggccagca 8050

 gactccatgg cccaattcgg tttcttcggt ggtgatgtga aaggagagaa 8100

 ttacactttt ttttttttta agtggcgtgg aggcctttgc ttccacattt 8150

 gtttttaacc cagaatttct gaaatagaga atttaagaac acatcaagta 8200

 ataaatatac agagaatata cttttttata aagcacatgc atctgctatt 8250

 gtgttgggtt ggtttcctct cttttccacg gacagtgttg tgtttctggc 8300

 atagggaaac tccaaacaac ttgcacacct ctactccgga gctgagattt 8350

 cttttacata gatgacctcg cttcaaatac gttaccttac tgatgatagg 8400

 atcttttctt gtagcactat accttgtggg aatttttttt taaatgtaca 8450

 cctgatttga gaagctgaag aaaacaaaat tttgaagcac tcactttgag 8500

 gagtacaggt aatgttttaa aaaattgcac aaaagaaaaa tgaatgtcga 8550

 aatgattcat tcagtgtttg aaagatatgg ctctgttgaa acaatgagtt 8600

 tcatactttg tttgtaaaaa aaaaaagcag agaagggttg aaagttacat 8650

 gtttttttgt atatagaaat ttgtcatgtc taaatgatca gatttgtatg 8700

 gttatggcct ggaagaatta ctacgtaaaa ggctcttaaa ctatacctat 8750

 gcttattgtt atttttgtta catatagccc tcgtctgagg gaggggaact 8800

 cggtattctg cgatttgaga atactgttca ttcctatgct gaaagtactt 8850

 ctctgagctc ccttcttagt ctaaactctt aagccattgc aacttctttt 8900

 tcttcagaga tgatgtttga cattttcagc acttcctgtt cctataaacc 8950

 caaagaatat aatcttgaac acgaagtgtt tgtaacaagg gatccaggct 9000

 accaatcaaa caggactcat tatggggaca aaaaaaaaaa aaattatttc 9050

 accttctttc cccccacacc tcatttaaat ggggggagta aaaacatgat 9100

 ttcaatgtaa atgcctcatt ttattttagt tttattttga tttttattta 9150

 atataaagag gccagaataa atacggagca tcttctcaga atagtattcc 9200

 tgtccaaaaa tcaagccgga cagtggaaac tggacagctg tggggatatt 9250

 aagcaccccc acttacaatt cttaaattca gaatctcgtc ccctcccttc 9300

 tcgttgaagg caactgttct ggtagctaac tttctcctgt gtaatggcgg 9350

 gagggaacac cggcttcagt ttttcatgtc cccatgactt gcatacaaat 9400

 ggttcaactg tattaaaatt aagtgcattt ggccaatagg tagtatctat 9450

 acaataacaa caatctctaa gaatttccat aacttttctt atctgaaagg 9500

 actcaagtct tccactgcag atacattgga ggcttcaccc acgttttctt 9550

 tccctttagt ttgtttgctg tctggatggc caatgagcct gtctcctttt 9600

 ctgtggccaa tctgaaggcc ttcgttggaa gtgttgttca cagtaatcct 9650

 taccaagata acatactgtc ctccagaata ccaagtatta ggtgacacta 9700

 gctcaagctg ttgtcttcag agcagttacc aagaagctcg gtgcacaggt 9750

 tttctctggt tcttacagga accacctact ctttcagttt tctggcccag 9800

 gagtggggta aatcctttag ttagtgcatt tgaacttggt acctgtgcat 9850

 tcagttctgt gaatactgcc ctttttggcg gggtttcctc atctccccag 9900

 cctgaactgc tcaactctaa acccaaatta gtgtcagccg aaaggaggtt 9950

 tcaagatagt cctgtcagta tttgtggtga ccttcagatt agacagtctt 10000

 catttccagc cagtggagtc ctggctccag agccatctct gagactccgt 10050

 actactggat gttttaatat cagatcatta cccaccatat gcctcccaca 10100

 ggccaaggga aaacagacac cagaacttgg gttgagggca ctaccagact 10150

 gacatggcca gtacagagga gaactaggga aggaatgatg ttttgcacct 10200

 tattgaaaag aaaattttaa gtgcatacat aatagttaag agcttttatt 10250

 gtgacaggag aacttttttc catatgcgtg catactctct gtaattccag 10300

 tgtaaaatat tgtacttgca ctagcttttt taaacaaata ttaaaaaatg 10350

 gaagaattca tattctattt tctaatcgtg gtgtgtctat ttgtaggata 10400

 cactcgagtc tgtttattga attttatggt ccctttcttt gatggtgctt 10450

 gcaggttttc taggtagaaa ttatttcatt attataataa aacaatgttt 10500

 gattcaaaat ttgaacaaaa ttgttttaaa taaattgtct gtataccagt 10550

 acaagtttat tgtttcagta tactcgtact aataaaataa cagtgccaat 10600

 tgcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 10650

 aaaaaaaaaa 10660

<210> 836
<211> 816
<212> PRT
<213> Homo sapien

<400> 836
 Met Lys Ser Asn Gln Glu Arg Ser Asn Glu Cys Leu Pro Pro Lys
   1               5                  10                  15

 Lys Arg Glu Ile Pro Ala Thr Ser Arg Ser Ser Glu Glu Lys Ala
                  20                  25                  30

 Pro Thr Leu Pro Ser Asp Asn His Arg Val Glu Gly Thr Ala Trp
                  35                  40                  45

 Leu Pro Gly Asn Pro Gly Gly Arg Gly His Gly Gly Gly Arg His
                  50                  55                  60

 Gly Pro Ala Gly Thr Ser Val Glu Leu Gly Leu Gln Gln Gly Ile
                  65                  70                  75

 Gly Leu His Lys Ala Leu Ser Thr Gly Leu Asp Tyr Ser Pro Pro
                  80                  85                  90

 Ser Ala Pro Arg Ser Val Pro Val Ala Thr Thr Leu Pro Ala Ala
                  95                 100                 105

 Tyr Ala Thr Pro Gln Pro Gly Thr Pro Val Ser Pro Val Gln Tyr
                 110                 115                 120

 Ala His Leu Pro His Thr Phe Gln Phe Ile Gly Ser Ser Gln Tyr
                 125                 130                 135

 Ser Gly Thr Tyr Ala Ser Phe Ile Pro Ser Gln Leu Ile Pro Pro
                 140                 145                 150

 Thr Ala Asn Pro Val Thr Ser Ala Val Ala Ser Ala Ala Gly Ala
                 155                 160                 165

 Thr Thr Pro Ser Gln Arg Ser Gln Leu Glu Ala Tyr Ser Thr Leu
                 170                 175                 180

 Leu Ala Asn Met Gly Ser Leu Ser Gln Thr Pro Gly His Lys Ala
                 185                 190                 195

 Glu Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln His Gln
                 200                 205                 210

 His Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                 215                 220                 225

 Gln His Leu Ser Arg Ala Pro Gly Leu Ile Thr Pro Gly Ser Pro
                 230                 235                 240

 Pro Pro Ala Gln Gln Asn Gln Tyr Val His Ile Ser Ser Ser Pro
                 245                 250                 255

 Gln Asn Thr Gly Arg Thr Ala Ser Pro Pro Ala Ile Pro Val His
                 260                 265                 270

 Leu His Pro His Gln Thr Met Ile Pro His Thr Leu Thr Leu Gly
                 275                 280                 285

 Pro Pro Ser Gln Val Val Met Gln Tyr Ala Asp Ser Gly Ser His
                 290                 295                 300

 Phe Val Pro Arg Glu Ala Thr Lys Lys Ala Glu Ser Ser Arg Leu
                 305                 310                 315

 Gln Gln Ala Ile Gln Ala Lys Glu Val Leu Asn Gly Glu Met Glu
                 320                 325                 330

 Lys Ser Arg Arg Tyr Gly Ala Pro Ser Ser Ala Asp Leu Gly Leu
                 335                 340                 345

 Gly Lys Ala Gly Gly Lys Ser Val Pro His Pro Tyr Glu Ser Arg
                 350                 355                 360

 His Val Val Val His Pro Ser Pro Ser Asp Tyr Ser Ser Arg Asp
                 365                 370                 375

 Pro Ser Gly Val Arg Ala Ser Val Met Val Leu Pro Asn Ser Asn
                 380                 385                 390

 Thr Pro Ala Ala Asp Leu Glu Val Gln Gln Ala Thr His Arg Glu
                 395                 400                 405

 Ala Ser Pro Ser Thr Leu Asn Asp Lys Ser Gly Leu His Leu Gly
                 410                 415                 420

 Lys Pro Gly His Arg Ser Tyr Ala Leu Ser Pro His Thr Val Ile
                 425                 430                 435

 Gln Thr Thr His Ser Ala Ser Glu Pro Leu Pro Val Gly Leu Pro
                 440                 445                 450

 Ala Thr Ala Phe Tyr Ala Gly Thr Gln Pro Pro Val Ile Gly Tyr
                 455                 460                 465

 Leu Ser Gly Gln Gln Gln Ala Ile Thr Tyr Ala Gly Ser Leu Pro
                 470                 475                 480

 Gln His Leu Val Ile Pro Gly Thr Gln Pro Leu Leu Ile Pro Val
                 485                 490                 495

 Gly Ser Thr Asp Met Glu Ala Ser Gly Ala Ala Pro Ala Ile Val
                 500                 505                 510

 Thr Ser Ser Pro Gln Phe Ala Ala Val Pro His Thr Phe Val Thr
                 515                 520                 525

 Thr Ala Leu Pro Lys Ser Glu Asn Phe Asn Pro Glu Ala Leu Val
                 530                 535                 540

 Thr Gln Ala Ala Tyr Pro Ala Met Val Gln Ala Gln Ile His Leu
                 545                 550                 555

 Pro Val Val Gln Ser Val Ala Ser Pro Ala Ala Ala Pro Pro Thr
                 560                 565                 570

 Leu Pro Pro Tyr Phe Met Lys Gly Ser Ile Ile Gln Leu Ala Asn
                 575                 580                 585

 Gly Glu Leu Lys Lys Val Glu Asp Leu Lys Thr Glu Asp Phe Ile
                 590                 595                 600

 Gln Ser Ala Glu Ile Ser Asn Asp Leu Lys Ile Asp Ser Ser Thr
                 605                 610                 615

 Val Glu Arg Ile Glu Asp Ser His Ser Pro Gly Val Ala Val Ile
                 620                 625                 630

 Gln Phe Ala Val Gly Glu His Arg Ala Gln Val Ser Val Glu Val
                 635                 640                 645

 Leu Val Glu Tyr Pro Phe Phe Val Phe Gly Gln Gly Trp Ser Ser
                 650                 655                 660

 Cys Cys Pro Glu Arg Thr Ser Gln Leu Phe Asp Leu Pro Cys Ser
                 665                 670                 675

 Lys Leu Ser Val Gly Asp Val Cys Ile Ser Leu Thr Leu Lys Asn
                 680                 685                 690

 Leu Lys Asn Gly Ser Val Lys Lys Gly Gln Pro Val Asp Pro Ala
                 695                 700                 705

 Ser Val Leu Leu Lys His Ser Lys Ala Asp Gly Leu Ala Gly Ser
                 710                 715                 720

 Arg His Arg Tyr Ala Glu Gln Glu Asn Gly Ile Asn Gln Gly Ser
                 725                 730                 735

 Ala Gln Met Leu Ser Glu Asn Gly Glu Leu Lys Phe Pro Glu Lys
                 740                 745                 750

 Met Gly Leu Pro Ala Ala Pro Phe Leu Thr Lys Ile Glu Pro Ser
                 755                 760                 765

 Lys Pro Ala Ala Thr Arg Lys Arg Arg Trp Ser Ala Pro Glu Ser
                 770                 775                 780

 Arg Lys Leu Glu Lys Ser Glu Asp Glu Pro Pro Leu Thr Leu Pro
                 785                 790                 795

 Lys Pro Ser Leu Ile Pro Gln Glu Val Lys Ile Cys Ile Glu Gly
                 800                 805                 810

 Arg Ser Asn Val Gly Lys
                 815

<210> 837
<211> 3597
<212> DNA
<213> Homo sapien

<400> 837
 ggcgaatgga gcaggggcgc gcagataatt aaagatttac acacagctgg 50

 aagaaatcat agagaagccg ggcgtggtgg ctcatgccta taatcccagc 100

 acttttggag gctgaggcgg gcagatcact tgagatcagg agttcgagac 150

 cagcctggtg ccttggcatc tcccaatggg gtggctttgc tctgggctcc 200

 tgttccctgt gagctgcctg gtcctgctgc aggtggcaag ctctgggaac 250

 atgaaggtct tgcaggagcc cacctgcgtc tccgactaca tgagcatctc 300

 tacttgcgag tggaagatga atggtcccac caattgcagc accgagctcc 350

 gcctgttgta ccagctggtt tttctgctct ccgaagccca cacgtgtatc 400

 cctgagaaca acggaggcgc ggggtgcgtg tgccacctgc tcatggatga 450

 cgtggtcagt gcggataact atacactgga cctgtgggct gggcagcagc 500

 tgctgtggaa gggctccttc aagcccagcg agcatgtgaa acccagggcc 550

 ccaggaaacc tgacagttca caccaatgtc tccgacactc tgctgctgac 600

 ctggagcaac ccgtatcccc ctgacaatta cctgtataat catctcacct 650

 atgcagtcaa catttggagt gaaaacgacc cggcagattt cagaatctat 700

 aacgtgacct acctagaacc ctccctccgc atcgcagcca gcaccctgaa 750

 gtctgggatt tcctacaggg cacgggtgag ggcctgggct cagtgctata 800

 acaccacctg gagtgagtgg agccccagca ccaagtggca caactcctac 850

 agggagccct tcgagcagca cctcctgctg ggcgtcagcg tttcctgcat 900

 tgtcatcctg gccgtctgcc tgttgtgcta tgtcagcatc accaagatta 950

 agaaagaatg gtgggatcag attcccaacc cagcccgcag ccgcctcgtg 1000

 gctataataa tccaggatgc tcaggggtca cagtgggaga agcggtcccg 1050

 aggccaggaa ccagccaagt gcccacactg gaagaattgt cttaccaagc 1100

 tcttgccctg ttttctggag cacaacatga aaagggatga agatcctcac 1150

 aaggctgcca aagagatgcc tttccagggc tctggaaaat cagcatggtg 1200

 cccagtggag atcagcaaga cagtcctctg gccagagagc atcagcgtgg 1250

 tgcgatgtgt ggagttgttt gaggccccgg tggagtgtga ggaggaggag 1300

 gaggtagagg aagaaaaagg gagcttctgt gcatcgcctg agagcagcag 1350

 ggatgacttc caggagggaa gggagggcat tgtggcccgg ctaacagaga 1400

 gcctgttcct ggacctgctc ggagaggaga atgggggctt ttgccagcag 1450

 gacatggggg agtcatgcct tcttccacct tcgggaagta cgagtgctca 1500

 catgccctgg gatgagttcc caagtgcagg gcccaaggag gcacctccct 1550

 ggggcaagga gcagcctctc cacctggagc caagtcctcc tgccagcccg 1600

 acccagagtc cagacaacct gacttgcaca gagacgcccc tcgtcatcgc 1650

 aggcaaccct gcttaccgca gcttcagcaa ctccctgagc cagtcaccgt 1700

 gtcccagaga gctgggtcca gacccactgc tggccagaca cctggaggaa 1750

 gtagaacccg agatgccctg tgtcccccag ctctctgagc caaccactgt 1800

 gccccaacct gagccagaaa cctgggagca gatcctccgc cgaaatgtcc 1850

 tccagcatgg ggcagctgca gcccccgtct cggcccccac cagtggctat 1900

 caggagtttg tacatgcggt ggagcagggt ggcacccagg ccagtgcggt 1950

 ggtgggcttg ggtcccccag gagaggctgg ttacaaggcc ttctcaagcc 2000

 tgcttgccag cagtgctgtg tccccagaga aatgtgggtt tggggctagc 2050

 agtggggaag aggggtataa gcctttccaa gacctcattc ctggctgccc 2100

 tggggaccct gccccagtcc ctgtcccctt gttcaccttt ggactggaca 2150

 gggagccacc tcgcagtccg cagagctcac atctcccaag cagctcccca 2200

 gagcacctgg gtctggagcc gggggaaaag gtagaggaca tgccaaagcc 2250

 cccacttccc caggagcagg ccacagaccc ccttgtggac agcctgggca 2300

 gtggcattgt ctactcagcc cttacctgcc acctgtgcgg ccacctgaaa 2350

 cagtgtcatg gccaggagga tggtggccag acccctgtca tggccagtcc 2400

 ttgctgtggc tgctgctgtg gagacaggtc ctcgccccct acaacccccc 2450

 tgagggcccc agacccctct ccaggtgggg ttccactgga ggccagtctg 2500

 tgtccggcct ccctggcacc ctcgggcatc tcagagaaga gtaaatcctc 2550

 atcatccttc catcctgccc ctggcaatgc tcagagctca agccagaccc 2600

 ccaaaatcgt gaactttgtc tccgtgggac ccacatacat gagggtctct 2650

 taggtgcatg tcctcttgtt gctgagtctg cagatgagga ctagggctta 2700

 tccatgcctg ggaaatgcca cctcctggaa ggcagccagg ctggcagatt 2750

 tccaaaagac ttgaagaacc atggtatgaa ggtgattggc cccactgacg 2800

 ttggcctaac actgggctgc agagactgga ccccgcccag cattgggctg 2850

 ggctcgccac atcccatgag agtagagggc actgggtcgc cgtgccccac 2900

 ggcaggcccc tgcaggaaaa ctgaggccct tgggcacctc gacttgtgaa 2950

 cgagttgttg gctgctccct ccacagcttc tgcagcagac tgtccctgtt 3000

 gtaactgccc aaggcatgtt ttgcccacca gatcatggcc cacgtggagg 3050

 cccacctgcc tctgtctcac tgaactagaa gccgagccta gaaactaaca 3100

 cagccatcaa gggaatgact tgggcggcct tgggaaatcg atgagaaatt 3150

 gaacttcagg gagggtggtc attgcctaga ggtgctcatt catttaacag 3200

 agcttcctta ggttgatgct ggaggcagaa tcccggctgt caaggggtgt 3250

 tcagttaagg ggagcaacag aggacatgaa aaattgctat gactaaagca 3300

 gggacaattt gctgccaaac acccatgccc agctgtatgg ctgggggctc 3350

 ctcgtatgca tggaaccccc agaataaata tgctcagcca ccctgtgggc 3400

 cgggcaatcc agacagcagg cataaggcac cagttaccct gcatgttggc 3450

 ccagacctca ggtgctaggg aaggcgggaa ccttgggttg agtaatgctc 3500

 gtctgtgtgt tttagtttca tcacctgtta tctgtgtttg ctgaggagag 3550

 tggaacagaa ggggtggagt tttgtataaa taaagtttct ttgtctc 3597

<210> 838
<211> 825
<212> PRT
<213> Homo sapien

<400> 838
 Met Gly Trp Leu Cys Ser Gly Leu Leu Phe Pro Val Ser Cys Leu
   1               5                  10                  15

 Val Leu Leu Gln Val Ala Ser Ser Gly Asn Met Lys Val Leu Gln
                  20                  25                  30

 Glu Pro Thr Cys Val Ser Asp Tyr Met Ser Ile Ser Thr Cys Glu
                  35                  40                  45

 Trp Lys Met Asn Gly Pro Thr Asn Cys Ser Thr Glu Leu Arg Leu
                  50                  55                  60

 Leu Tyr Gln Leu Val Phe Leu Leu Ser Glu Ala His Thr Cys Ile
                  65                  70                  75

 Pro Glu Asn Asn Gly Gly Ala Gly Cys Val Cys His Leu Leu Met
                  80                  85                  90

 Asp Asp Val Val Ser Ala Asp Asn Tyr Thr Leu Asp Leu Trp Ala
                  95                 100                 105

 Gly Gln Gln Leu Leu Trp Lys Gly Ser Phe Lys Pro Ser Glu His
                 110                 115                 120

 Val Lys Pro Arg Ala Pro Gly Asn Leu Thr Val His Thr Asn Val
                 125                 130                 135

 Ser Asp Thr Leu Leu Leu Thr Trp Ser Asn Pro Tyr Pro Pro Asp
                 140                 145                 150

 Asn Tyr Leu Tyr Asn His Leu Thr Tyr Ala Val Asn Ile Trp Ser
                 155                 160                 165

 Glu Asn Asp Pro Ala Asp Phe Arg Ile Tyr Asn Val Thr Tyr Leu
                 170                 175                 180

 Glu Pro Ser Leu Arg Ile Ala Ala Ser Thr Leu Lys Ser Gly Ile
                 185                 190                 195

 Ser Tyr Arg Ala Arg Val Arg Ala Trp Ala Gln Cys Tyr Asn Thr
                 200                 205                 210

 Thr Trp Ser Glu Trp Ser Pro Ser Thr Lys Trp His Asn Ser Tyr
                 215                 220                 225

 Arg Glu Pro Phe Glu Gln His Leu Leu Leu Gly Val Ser Val Ser
                 230                 235                 240

 Cys Ile Val Ile Leu Ala Val Cys Leu Leu Cys Tyr Val Ser Ile
                 245                 250                 255

 Thr Lys Ile Lys Lys Glu Trp Trp Asp Gln Ile Pro Asn Pro Ala
                 260                 265                 270

 Arg Ser Arg Leu Val Ala Ile Ile Ile Gln Asp Ala Gln Gly Ser
                 275                 280                 285

 Gln Trp Glu Lys Arg Ser Arg Gly Gln Glu Pro Ala Lys Cys Pro
                 290                 295                 300

 His Trp Lys Asn Cys Leu Thr Lys Leu Leu Pro Cys Phe Leu Glu
                 305                 310                 315

 His Asn Met Lys Arg Asp Glu Asp Pro His Lys Ala Ala Lys Glu
                 320                 325                 330

 Met Pro Phe Gln Gly Ser Gly Lys Ser Ala Trp Cys Pro Val Glu
                 335                 340                 345

 Ile Ser Lys Thr Val Leu Trp Pro Glu Ser Ile Ser Val Val Arg
                 350                 355                 360

 Cys Val Glu Leu Phe Glu Ala Pro Val Glu Cys Glu Glu Glu Glu
                 365                 370                 375

 Glu Val Glu Glu Glu Lys Gly Ser Phe Cys Ala Ser Pro Glu Ser
                 380                 385                 390

 Ser Arg Asp Asp Phe Gln Glu Gly Arg Glu Gly Ile Val Ala Arg
                 395                 400                 405

 Leu Thr Glu Ser Leu Phe Leu Asp Leu Leu Gly Glu Glu Asn Gly
                 410                 415                 420

 Gly Phe Cys Gln Gln Asp Met Gly Glu Ser Cys Leu Leu Pro Pro
                 425                 430                 435

 Ser Gly Ser Thr Ser Ala His Met Pro Trp Asp Glu Phe Pro Ser
                 440                 445                 450

 Ala Gly Pro Lys Glu Ala Pro Pro Trp Gly Lys Glu Gln Pro Leu
                 455                 460                 465

 His Leu Glu Pro Ser Pro Pro Ala Ser Pro Thr Gln Ser Pro Asp
                 470                 475                 480

 Asn Leu Thr Cys Thr Glu Thr Pro Leu Val Ile Ala Gly Asn Pro
                 485                 490                 495

 Ala Tyr Arg Ser Phe Ser Asn Ser Leu Ser Gln Ser Pro Cys Pro
                 500                 505                 510

 Arg Glu Leu Gly Pro Asp Pro Leu Leu Ala Arg His Leu Glu Glu
                 515                 520                 525

 Val Glu Pro Glu Met Pro Cys Val Pro Gln Leu Ser Glu Pro Thr
                 530                 535                 540

 Thr Val Pro Gln Pro Glu Pro Glu Thr Trp Glu Gln Ile Leu Arg
                 545                 550                 555

 Arg Asn Val Leu Gln His Gly Ala Ala Ala Ala Pro Val Ser Ala
                 560                 565                 570

 Pro Thr Ser Gly Tyr Gln Glu Phe Val His Ala Val Glu Gln Gly
                 575                 580                 585

 Gly Thr Gln Ala Ser Ala Val Val Gly Leu Gly Pro Pro Gly Glu
                 590                 595                 600

 Ala Gly Tyr Lys Ala Phe Ser Ser Leu Leu Ala Ser Ser Ala Val
                 605                 610                 615

 Ser Pro Glu Lys Cys Gly Phe Gly Ala Ser Ser Gly Glu Glu Gly
                 620                 625                 630

 Tyr Lys Pro Phe Gln Asp Leu Ile Pro Gly Cys Pro Gly Asp Pro
                 635                 640                 645

 Ala Pro Val Pro Val Pro Leu Phe Thr Phe Gly Leu Asp Arg Glu
                 650                 655                 660

 Pro Pro Arg Ser Pro Gln Ser Ser His Leu Pro Ser Ser Ser Pro
                 665                 670                 675

 Glu His Leu Gly Leu Glu Pro Gly Glu Lys Val Glu Asp Met Pro
                 680                 685                 690

 Lys Pro Pro Leu Pro Gln Glu Gln Ala Thr Asp Pro Leu Val Asp
                 695                 700                 705

 Ser Leu Gly Ser Gly Ile Val Tyr Ser Ala Leu Thr Cys His Leu
                 710                 715                 720

 Cys Gly His Leu Lys Gln Cys His Gly Gln Glu Asp Gly Gly Gln
                 725                 730                 735

 Thr Pro Val Met Ala Ser Pro Cys Cys Gly Cys Cys Cys Gly Asp
                 740                 745                 750

 Arg Ser Ser Pro Pro Thr Thr Pro Leu Arg Ala Pro Asp Pro Ser
                 755                 760                 765

 Pro Gly Gly Val Pro Leu Glu Ala Ser Leu Cys Pro Ala Ser Leu
                 770                 775                 780

 Ala Pro Ser Gly Ile Ser Glu Lys Ser Lys Ser Ser Ser Ser Phe
                 785                 790                 795

 His Pro Ala Pro Gly Asn Ala Gln Ser Ser Ser Gln Thr Pro Lys
                 800                 805                 810

 Ile Val Asn Phe Val Ser Val Gly Pro Thr Tyr Met Arg Val Ser
                 815                 820                 825

<210> 839
<211> 3287
<212> DNA
<213> Homo sapien

<400> 839
 agactgaggc ggaggcagcc ccgcgccgcg ccggacccga gcatatttca 50

 ttttctgtca ttggactttg agccattaga accatgagca actacagtgt 100

 gtcactggtt ggcccagctc cttggggttt ccggctgcag ggcggtaagg 150

 atttcaacat gcctctgaca atctctagtc taaaagatgg cggcaaggca 200

 gcccaggcaa atgtaagaat aggcgatgtg gttctcagca ttgatggaat 250

 aaatgcacaa ggaatgactc atcttgaagc ccagaataag attaagggtt 300

 gtacaggctc tttgaatatg actctgcaaa gagcatctgc tgcacccaag 350

 cctgagccgg ttcctgttca aaagggagaa cctaaagaag tagttaaacc 400

 tgtgcccatt acatctcctg ctgtgtccaa agtcacttcc acaaacaaca 450

 tggcctacaa taaggcacca cggccttttg gttctgtgtc ttcaccaaaa 500

 gtcacatcca tcccatcacc atcgtctgcc ttcaccccag cccatgcgac 550

 cacctcatca catgcttccc cttcacccgt ggctgccgtc actcctcccc 600

 tgttcgctgc atctggactg catgctaatg ccaatcttag tgctgaccag 650

 tctccatctg cactgagcgc tggtaaaact gcagttaatg tcccacggca 700

 gcccacagtc accagcgtgt gttccgagac ttctcaggag ctagcagagg 750

 gacagagaag aggatcccag ggtgacagta aacagcaaaa tggcccacca 800

 agaaaacaca ttgtggagcg ctatacagag ttttatcatg tacccactca 850

 cagtgatgcc agcaagaaga gactgattga ggatactgaa gactggcgtc 900

 caagaactgg aacaactcag tctcgctctt tccgaatcct tgcccagatc 950

 actgggactg aacatttgaa agaatctgaa gccgataata caaagaaggc 1000

 aaataactct caggagcctt ctccgcagtt ggcttccttg gtagcttcca 1050

 cacggagcat gcccgagagc ctggacagcc caacctctgg cagaccaggg 1100

 gttaccagcc tcacaactgc agctgccttc aagcctgtag gatccactgg 1150

 cgtcatcaag tcaccaagct ggcaacggcc aaaccaagga gtaccttcca 1200

 ctggaagaat ctcaaacagc gctacttact caggatcagt ggcaccagcc 1250

 aactcagctt tgggacaaac ccagccaagt gaccaggaca ctttagtgca 1300

 aagagctgag cacattccag cagggaaacg aactccgatg tgcgcccatt 1350

 gtaaccaggt catcagagga ccattcttag tggcactggg gaaatcttgg 1400

 cacccagaag aattcaactg cgctcactgc aaaaatacaa tggcctacat 1450

 tggatttgta gaggagaaag gagccctgta ttgtgagctg tgctatgaga 1500

 aattctttgc ccctgaatgt ggtcgatgcc aaaggaagat ccttggagaa 1550

 gtcatcaatg cgttgaaaca aacttggcat gtttcctgtt ttgtgtgtgt 1600

 agcctgtgga aagcccattc ggaacaatgt ttttcacttg gaggatggtg 1650

 aaccctactg tgagactgat tattatgccc tctttggtac tatatgccat 1700

 ggatgtgaat ttcccataga agctggtgac atgttcctgg aagctctggg 1750

 ctacacctgg catgacactt gctttgtatg ctcagtgtgt tgtgaaagtt 1800

 tggaaggtca gacctttttc tccaagaagg acaagcccct gtgtaagaaa 1850

 catgctcatt ctgtgaattt ttgaaagtca acagttcagg agaagagaag 1900

 gaatttgaag agaaaaagga aaattaaaat tactaattaa tttttagatt 1950

 caatatttat atggagtttt gaaaaataat agtggccctg aaggaataaa 2000

 ttccagcttt aaaaaccaag tctgaggaaa tatttggctt cataaagtaa 2050

 agagacggtt tggcatttat tattactttt tcctgtattt tatgcccata 2100

 aaataagctt tataaaaacc aatttcctga tggactatta aattcatctt 2150

 agaataaatt agtgaagaat ttaattttag aataaataat ccaatctgaa 2200

 ataattatac cttctttcct tgttaggtag ttatgagtaa atctgcaaaa 2250

 ggcaatgaaa atgccttaaa ttttatcaat aacagaatta ttgtatttaa 2300

 aaaaaaacta atacttatct ttaaaatagt aaataggatt ttaaacagag 2350

 aattttatca gtaataggtg tcagttttta aaaaattgct tgtaggctga 2400

 gcgcggtggc tcacgcctgt aatcccagca ctttgggagg ccaaggtggg 2450

 tggaccacat gaggtcagga gtttgagatc agcctggcca acatggtgaa 2500

 accccatctc tactaaaaat acaaaaatta gccggacgca gtggcacgcg 2550

 cctgtaatcc cagctactca agaggctgag gcacgagaat cacttgaacc 2600

 cgggagggag aggttgcagt gagccaagat cgtaccactg cactccagcc 2650

 tgggtgacag agtgagactc cgtctccaaa aaaaaacttt gcttgtatat 2700

 tatttttgcc ttacagtgga tcattctagt aggaaaggac aataagattt 2750

 tttatcaaaa tgtgtcatgc cagtaagaga tgttatattc ttttcttatt 2800

 tcttccccac ccaaaaataa gctaccatat agcttataag tctcaaattt 2850

 ttgcctttta ctaaaatgtg attgtttctg ttcattgtgt atgcttcatc 2900

 acctatatta ggcaaattcc attttttccc ttgcgctaag gtaaagattt 2950

 aattaaataa ttttggcctc tcatagtttt ctctctcttt aaagagaata 3000

 aatagagggc caggtgtggt ggctcacgcc tgtgatccca gcactttggg 3050

 aggccaagac gggcggatca tgaggtcaag agatcaagat catcctggcc 3100

 aacatggtga aaccctgtct ctactaaaaa tacaaaaatg agctgggcat 3150

 ggtggggcgt gcctgtagtc ccatgtactt gggaggctga ggcaggaaaa 3200

 ttcttgaacc caggagacgg aagttgcagt gagctgagat cacaccactg 3250

 cactccagcc tggtgacaga gcaagactcc ggctctt 3287

<210> 840
<211> 596
<212> PRT
<213> Homo sapien

<400> 840
 Met Ser Asn Tyr Ser Val Ser Leu Val Gly Pro Ala Pro Trp Gly
   1               5                  10                  15

 Phe Arg Leu Gln Gly Gly Lys Asp Phe Asn Met Pro Leu Thr Ile
                  20                  25                  30

 Ser Ser Leu Lys Asp Gly Gly Lys Ala Ala Gln Ala Asn Val Arg
                  35                  40                  45

 Ile Gly Asp Val Val Leu Ser Ile Asp Gly Ile Asn Ala Gln Gly
                  50                  55                  60

 Met Thr His Leu Glu Ala Gln Asn Lys Ile Lys Gly Cys Thr Gly
                  65                  70                  75

 Ser Leu Asn Met Thr Leu Gln Arg Ala Ser Ala Ala Pro Lys Pro
                  80                  85                  90

 Glu Pro Val Pro Val Gln Lys Gly Glu Pro Lys Glu Val Val Lys
                  95                 100                 105

 Pro Val Pro Ile Thr Ser Pro Ala Val Ser Lys Val Thr Ser Thr
                 110                 115                 120

 Asn Asn Met Ala Tyr Asn Lys Ala Pro Arg Pro Phe Gly Ser Val
                 125                 130                 135

 Ser Ser Pro Lys Val Thr Ser Ile Pro Ser Pro Ser Ser Ala Phe
                 140                 145                 150

 Thr Pro Ala His Ala Thr Thr Ser Ser His Ala Ser Pro Ser Pro
                 155                 160                 165

 Val Ala Ala Val Thr Pro Pro Leu Phe Ala Ala Ser Gly Leu His
                 170                 175                 180

 Ala Asn Ala Asn Leu Ser Ala Asp Gln Ser Pro Ser Ala Leu Ser
                 185                 190                 195

 Ala Gly Lys Thr Ala Val Asn Val Pro Arg Gln Pro Thr Val Thr
                 200                 205                 210

 Ser Val Cys Ser Glu Thr Ser Gln Glu Leu Ala Glu Gly Gln Arg
                 215                 220                 225

 Arg Gly Ser Gln Gly Asp Ser Lys Gln Gln Asn Gly Pro Pro Arg
                 230                 235                 240

 Lys His Ile Val Glu Arg Tyr Thr Glu Phe Tyr His Val Pro Thr
                 245                 250                 255

 His Ser Asp Ala Ser Lys Lys Arg Leu Ile Glu Asp Thr Glu Asp
                 260                 265                 270

 Trp Arg Pro Arg Thr Gly Thr Thr Gln Ser Arg Ser Phe Arg Ile
                 275                 280                 285

 Leu Ala Gln Ile Thr Gly Thr Glu His Leu Lys Glu Ser Glu Ala
                 290                 295                 300

 Asp Asn Thr Lys Lys Ala Asn Asn Ser Gln Glu Pro Ser Pro Gln
                 305                 310                 315

 Leu Ala Ser Leu Val Ala Ser Thr Arg Ser Met Pro Glu Ser Leu
                 320                 325                 330

 Asp Ser Pro Thr Ser Gly Arg Pro Gly Val Thr Ser Leu Thr Thr
                 335                 340                 345

 Ala Ala Ala Phe Lys Pro Val Gly Ser Thr Gly Val Ile Lys Ser
                 350                 355                 360

 Pro Ser Trp Gln Arg Pro Asn Gln Gly Val Pro Ser Thr Gly Arg
                 365                 370                 375

 Ile Ser Asn Ser Ala Thr Tyr Ser Gly Ser Val Ala Pro Ala Asn
                 380                 385                 390

 Ser Ala Leu Gly Gln Thr Gln Pro Ser Asp Gln Asp Thr Leu Val
                 395                 400                 405

 Gln Arg Ala Glu His Ile Pro Ala Gly Lys Arg Thr Pro Met Cys
                 410                 415                 420

 Ala His Cys Asn Gln Val Ile Arg Gly Pro Phe Leu Val Ala Leu
                 425                 430                 435

 Gly Lys Ser Trp His Pro Glu Glu Phe Asn Cys Ala His Cys Lys
                 440                 445                 450

 Asn Thr Met Ala Tyr Ile Gly Phe Val Glu Glu Lys Gly Ala Leu
                 455                 460                 465

 Tyr Cys Glu Leu Cys Tyr Glu Lys Phe Phe Ala Pro Glu Cys Gly
                 470                 475                 480

 Arg Cys Gln Arg Lys Ile Leu Gly Glu Val Ile Asn Ala Leu Lys
                 485                 490                 495

 Gln Thr Trp His Val Ser Cys Phe Val Cys Val Ala Cys Gly Lys
                 500                 505                 510

 Pro Ile Arg Asn Asn Val Phe His Leu Glu Asp Gly Glu Pro Tyr
                 515                 520                 525

 Cys Glu Thr Asp Tyr Tyr Ala Leu Phe Gly Thr Ile Cys His Gly
                 530                 535                 540

 Cys Glu Phe Pro Ile Glu Ala Gly Asp Met Phe Leu Glu Ala Leu
                 545                 550                 555

 Gly Tyr Thr Trp His Asp Thr Cys Phe Val Cys Ser Val Cys Cys
                 560                 565                 570

 Glu Ser Leu Glu Gly Gln Thr Phe Phe Ser Lys Lys Asp Lys Pro
                 575                 580                 585

 Leu Cys Lys Lys His Ala His Ser Val Asn Phe
                 590                 595

<210> 841
<211> 3287
<212> DNA
<213> Homo sapien

<400> 841
 agactgaggc ggaggcagcc ccgcgccgcg ccggacccga gcatatttca 50

 ttttctgtca ttggactttg agccattaga accatgagca actacagtgt 100

 gtcactggtt ggcccagctc cttggggttt ccggctgcag ggcggtaagg 150

 atttcaacat gcctctgaca atctctagtc taaaagatgg cggcaaggca 200

 gcccaggcaa atgtaagaat aggcgatgtg gttctcagca ttgatggaat 250

 aaatgcacaa ggaatgactc atcttgaagc ccagaataag attaagggtt 300

 gtacaggctc tttgaatatg actctgcaaa gagcatctgc tgcacccaag 350

 cctgagccgg ttcctgttca aaagggagaa cctaaagaag tagttaaacc 400

 tgtgcccatt acatctcctg ctgtgtccaa agtcacttcc acaaacaaca 450

 tggcctacaa taaggcacca cggccttttg gttctgtgtc ttcaccaaaa 500

 gtcacatcca tcccatcacc atcgtctgcc ttcaccccag cccatgcgac 550

 cacctcatca catgcttccc cttcacccgt ggctgccgtc actcctcccc 600

 tgttcgctgc atctggactg catgctaatg ccaatcttag tgctgaccag 650

 tctccatctg cactgagcgc tggtaaaact gcagttaatg tcccacggca 700

 gcccacagtc accagcgtgt gttccgagac ttctcaggag ctagcagagg 750

 gacagagaag aggatcccag ggtgacagta aacagcaaaa tggcccacca 800

 agaaaacaca ttgtggagcg ctatacagag ttttatcatg tacccactca 850

 cagtgatgcc agcaagaaga gactgattga ggatactgaa gactggcgtc 900

 caagaactgg aacaactcag tctcgctctt tccgaatcct tgcccagatc 950

 actgggactg aacatttgaa agaatctgaa gccgataata caaagaaggc 1000

 aaataactct caggagcctt ctccgcagtt ggcttccttg gtagcttcca 1050

 cacggagcat gcccgagagc ctggacagcc caacctctgg cagaccaggg 1100

 gttaccagcc tcacaactgc agctgccttc aagcctgtag gatccactgg 1150

 cgtcatcaag tcaccaagct ggcaacggcc aaaccaagga gtaccttcca 1200

 ctggaagaat ctcaaacagc gctacttact caggatcagt ggcaccagcc 1250

 aactcagctt tgggacaaac ccagccaagt gaccaggaca ctttagtgca 1300

 aagagctgag cacattccag cagggaaacg aactccgatg tgcgcccatt 1350

 gtaaccaggt catcagagga ccattcttag tggcactggg gaaatcttgg 1400

 cacccagaag aattcaactg cgctcactgc aaaaatacaa tggcctacat 1450

 tggatttgta gaggagaaag gagccctgta ttgtgagctg tgctatgaga 1500

 aattctttgc ccctgaatgt ggtcgatgcc aaaggaagat ccttggagaa 1550

 gtcatcaatg cgttgaaaca aacttggcat gtttcctgtt ttgtgtgtgt 1600

 agcctgtgga aagcccattc ggaacaatgt ttttcacttg gaggatggtg 1650

 aaccctactg tgagactgat tattatgccc tctttggtac tatatgccat 1700

 ggatgtgaat ttcccataga agctggtgac atgttcctgg aagctctggg 1750

 ctacacctgg catgacactt gctttgtatg ctcagtgtgt tgtgaaagtt 1800

 tggaaggtca gacctttttc tccaagaagg acaagcccct gtgtaagaaa 1850

 catgctcatt ctgtgaattt ttgaaagtca acagttcagg agaagagaag 1900

 gaatttgaag agaaaaagga aaattaaaat tactaattaa tttttagatt 1950

 caatatttat atggagtttt gaaaaataat agtggccctg aaggaataaa 2000

 ttccagcttt aaaaaccaag tctgaggaaa tatttggctt cataaagtaa 2050

 agagacggtt tggcatttat tattactttt tcctgtattt tatgcccata 2100

 aaataagctt tataaaaacc aatttcctga tggactatta aattcatctt 2150

 agaataaatt agtgaagaat ttaattttag aataaataat ccaatctgaa 2200

 ataattatac cttctttcct tgttaggtag ttatgagtaa atctgcaaaa 2250

 ggcaatgaaa atgccttaaa ttttatcaat aacagaatta ttgtatttaa 2300

 aaaaaaacta atacttatct ttaaaatagt aaataggatt ttaaacagag 2350

 aattttatca gtaataggtg tcagttttta aaaaattgct tgtaggctga 2400

 gcgcggtggc tcacgcctgt aatcccagca ctttgggagg ccaaggtggg 2450

 tggaccacat gaggtcagga gtttgagatc agcctggcca acatggtgaa 2500

 accccatctc tactaaaaat acaaaaatta gccggacgca gtggcacgcg 2550

 cctgtaatcc cagctactca agaggctgag gcacgagaat cacttgaacc 2600

 cgggagggag aggttgcagt gagccaagat cgtaccactg cactccagcc 2650

 tgggtgacag agtgagactc cgtctccaaa aaaaaacttt gcttgtatat 2700

 tatttttgcc ttacagtgga tcattctagt aggaaaggac aataagattt 2750

 tttatcaaaa tgtgtcatgc cagtaagaga tgttatattc ttttcttatt 2800

 tcttccccac ccaaaaataa gctaccatat agcttataag tctcaaattt 2850

 ttgcctttta ctaaaatgtg attgtttctg ttcattgtgt atgcttcatc 2900

 acctatatta ggcaaattcc attttttccc ttgcgctaag gtaaagattt 2950

 aattaaataa ttttggcctc tcatagtttt ctctctcttt aaagagaata 3000

 aatagagggc caggtgtggt ggctcacgcc tgtgatccca gcactttggg 3050

 aggccaagac gggcggatca tgaggtcaag agatcaagat catcctggcc 3100

 aacatggtga aaccctgtct ctactaaaaa tacaaaaatg agctgggcat 3150

 ggtggggcgt gcctgtagtc ccatgtactt gggaggctga ggcaggaaaa 3200

 ttcttgaacc caggagacgg aagttgcagt gagctgagat cacaccactg 3250

 cactccagcc tggtgacaga gcaagactcc ggctctt 3287

<210> 842
<211> 596
<212> PRT
<213> Homo sapien

<400> 842
 Met Ser Asn Tyr Ser Val Ser Leu Val Gly Pro Ala Pro Trp Gly
   1               5                  10                  15

 Phe Arg Leu Gln Gly Gly Lys Asp Phe Asn Met Pro Leu Thr Ile
                  20                  25                  30

 Ser Ser Leu Lys Asp Gly Gly Lys Ala Ala Gln Ala Asn Val Arg
                  35                  40                  45

 Ile Gly Asp Val Val Leu Ser Ile Asp Gly Ile Asn Ala Gln Gly
                  50                  55                  60

 Met Thr His Leu Glu Ala Gln Asn Lys Ile Lys Gly Cys Thr Gly
                  65                  70                  75

 Ser Leu Asn Met Thr Leu Gln Arg Ala Ser Ala Ala Pro Lys Pro
                  80                  85                  90

 Glu Pro Val Pro Val Gln Lys Gly Glu Pro Lys Glu Val Val Lys
                  95                 100                 105

 Pro Val Pro Ile Thr Ser Pro Ala Val Ser Lys Val Thr Ser Thr
                 110                 115                 120

 Asn Asn Met Ala Tyr Asn Lys Ala Pro Arg Pro Phe Gly Ser Val
                 125                 130                 135

 Ser Ser Pro Lys Val Thr Ser Ile Pro Ser Pro Ser Ser Ala Phe
                 140                 145                 150

 Thr Pro Ala His Ala Thr Thr Ser Ser His Ala Ser Pro Ser Pro
                 155                 160                 165

 Val Ala Ala Val Thr Pro Pro Leu Phe Ala Ala Ser Gly Leu His
                 170                 175                 180

 Ala Asn Ala Asn Leu Ser Ala Asp Gln Ser Pro Ser Ala Leu Ser
                 185                 190                 195

 Ala Gly Lys Thr Ala Val Asn Val Pro Arg Gln Pro Thr Val Thr
                 200                 205                 210

 Ser Val Cys Ser Glu Thr Ser Gln Glu Leu Ala Glu Gly Gln Arg
                 215                 220                 225

 Arg Gly Ser Gln Gly Asp Ser Lys Gln Gln Asn Gly Pro Pro Arg
                 230                 235                 240

 Lys His Ile Val Glu Arg Tyr Thr Glu Phe Tyr His Val Pro Thr
                 245                 250                 255

 His Ser Asp Ala Ser Lys Lys Arg Leu Ile Glu Asp Thr Glu Asp
                 260                 265                 270

 Trp Arg Pro Arg Thr Gly Thr Thr Gln Ser Arg Ser Phe Arg Ile
                 275                 280                 285

 Leu Ala Gln Ile Thr Gly Thr Glu His Leu Lys Glu Ser Glu Ala
                 290                 295                 300

 Asp Asn Thr Lys Lys Ala Asn Asn Ser Gln Glu Pro Ser Pro Gln
                 305                 310                 315

 Leu Ala Ser Leu Val Ala Ser Thr Arg Ser Met Pro Glu Ser Leu
                 320                 325                 330

 Asp Ser Pro Thr Ser Gly Arg Pro Gly Val Thr Ser Leu Thr Thr
                 335                 340                 345

 Ala Ala Ala Phe Lys Pro Val Gly Ser Thr Gly Val Ile Lys Ser
                 350                 355                 360

 Pro Ser Trp Gln Arg Pro Asn Gln Gly Val Pro Ser Thr Gly Arg
                 365                 370                 375

 Ile Ser Asn Ser Ala Thr Tyr Ser Gly Ser Val Ala Pro Ala Asn
                 380                 385                 390

 Ser Ala Leu Gly Gln Thr Gln Pro Ser Asp Gln Asp Thr Leu Val
                 395                 400                 405

 Gln Arg Ala Glu His Ile Pro Ala Gly Lys Arg Thr Pro Met Cys
                 410                 415                 420

 Ala His Cys Asn Gln Val Ile Arg Gly Pro Phe Leu Val Ala Leu
                 425                 430                 435

 Gly Lys Ser Trp His Pro Glu Glu Phe Asn Cys Ala His Cys Lys
                 440                 445                 450

 Asn Thr Met Ala Tyr Ile Gly Phe Val Glu Glu Lys Gly Ala Leu
                 455                 460                 465

 Tyr Cys Glu Leu Cys Tyr Glu Lys Phe Phe Ala Pro Glu Cys Gly
                 470                 475                 480

 Arg Cys Gln Arg Lys Ile Leu Gly Glu Val Ile Asn Ala Leu Lys
                 485                 490                 495

 Gln Thr Trp His Val Ser Cys Phe Val Cys Val Ala Cys Gly Lys
                 500                 505                 510

 Pro Ile Arg Asn Asn Val Phe His Leu Glu Asp Gly Glu Pro Tyr
                 515                 520                 525

 Cys Glu Thr Asp Tyr Tyr Ala Leu Phe Gly Thr Ile Cys His Gly
                 530                 535                 540

 Cys Glu Phe Pro Ile Glu Ala Gly Asp Met Phe Leu Glu Ala Leu
                 545                 550                 555

 Gly Tyr Thr Trp His Asp Thr Cys Phe Val Cys Ser Val Cys Cys
                 560                 565                 570

 Glu Ser Leu Glu Gly Gln Thr Phe Phe Ser Lys Lys Asp Lys Pro
                 575                 580                 585

 Leu Cys Lys Lys His Ala His Ser Val Asn Phe
                 590                 595

<210> 843
<211> 1000
<212> DNA
<213> Homo sapien

<400> 843
 aattcgccag cggcgcggtg gacagtcatg gcggcccggc gcggggctct 50

 catagtgctg gagggcgtgg accgcgccgg gaagagcacg cagagccgca 100

 agctggtgga agcgctgtcg cgcgggccac cgcccgaact gctccggttc 150

 ccggaaagat caactgaaat cggcaaactt ctgagttcct acttgcaaaa 200

 gaaaagtgac gtggaggatc actcggtgca cctgcttttt tctgcaaatc 250

 gctgggaaca agtgccgtta attaaggaaa agttgagcca gggcgtgacc 300

 ctcgtcgtgg acagatacgc attttctggt gtggccttca ccggtgccaa 350

 ggagaatttt tccctagact ggtgtaaaca gccagacgtg ggccttccca 400

 aacccgacct ggtcctgttc ctccagttac agctggcgga tgctgccaag 450

 cggggagcgt ttggccatga gcgctatgag aacggggctt tccaggagcg 500

 ggcgctccgg tgtttccacc agctcatgaa agacacgact ttgaactgga 550

 agatggtgga tgcttccaaa agactcgaag ctgtccatga ggaactccgc 600

 gtgctctctg aggacgccat ccgcactgcc acagagaagc cgctggggga 650

 gctatggaag tgacccaagg ctgcccactg gagacgcctc tccctgcagt 700

 cccccgagag gtgggagact cgcggaaggc cccgtcccca gcggagtcca 750

 gaccccacaa cttcaggagc tctttcccgg cagcagagat ctgcaggctg 800

 cctcttctgc cccggagctg gggtgcactg gggacccccg tggtggggac 850

 cttggcagtg tggacatgag cagagcgatg gagcagtctc ctgccctctc 900

 ccctgtcctg atggcactct gttgtatttt cttactgaag ttcagtgata 950

 actctgagca gtttcattgt gatcactgta aatggtaatc agttggaatt 1000

<210> 844
<211> 211
<212> PRT
<213> Homo sapien

<400> 844
 Met Ala Ala Arg Arg Gly Ala Leu Ile Val Leu Glu Gly Val Asp
   1               5                  10                  15

 Arg Ala Gly Lys Ser Thr Gln Ser Arg Lys Leu Val Glu Ala Leu
                  20                  25                  30

 Ser Arg Gly Pro Pro Pro Glu Leu Leu Arg Phe Pro Glu Arg Ser
                  35                  40                  45

 Thr Glu Ile Gly Lys Leu Leu Ser Ser Tyr Leu Gln Lys Lys Ser
                  50                  55                  60

 Asp Val Glu Asp His Ser Val His Leu Leu Phe Ser Ala Asn Arg
                  65                  70                  75

 Trp Glu Gln Val Pro Leu Ile Lys Glu Lys Leu Ser Gln Gly Val
                  80                  85                  90

 Thr Leu Val Val Asp Arg Tyr Ala Phe Ser Gly Val Ala Phe Thr
                  95                 100                 105

 Gly Ala Lys Glu Asn Phe Ser Leu Asp Trp Cys Lys Gln Pro Asp
                 110                 115                 120

 Val Gly Leu Pro Lys Pro Asp Leu Val Leu Phe Leu Gln Leu Gln
                 125                 130                 135

 Leu Ala Asp Ala Ala Lys Arg Gly Ala Phe Gly His Glu Arg Tyr
                 140                 145                 150

 Glu Asn Gly Ala Phe Gln Glu Arg Ala Leu Arg Cys Phe His Gln
                 155                 160                 165

 Leu Met Lys Asp Thr Thr Leu Asn Trp Lys Met Val Asp Ala Ser
                 170                 175                 180

 Lys Arg Leu Glu Ala Val His Glu Glu Leu Arg Val Leu Ser Glu
                 185                 190                 195

 Asp Ala Ile Arg Thr Ala Thr Glu Lys Pro Leu Gly Glu Leu Trp
                 200                 205                 210

 Lys


<210> 845
<211> 3301
<212> DNA
<213> Homo sapien

<400> 845
 aggagccagg aagagagctg tgaccagcag cgtcccttat tcgcttggcc 50

 ttggttcctg tttgcactgg ctacagcagg gcactggccc ctactgtcac 100

 cgccacctac acaaagaccc tatctctgag cgctgcagcc tactgttcag 150

 ccccaggttt gaggatggat gccctggacg cttcgaagct actggatgag 200

 gagctgtatt caagacagct gtatgtgctg ggctcacctg ccatgcagag 250

 gattcaggga gccagggtcc tggtgtcagg cctgcagggc ctgggggccg 300

 aggtggccaa gaacttggtt ctgatgggtg tgggcagcct cactctgcat 350

 gatccccacc ccacctgctg gtccgacctg gctgcccagt ttctcctctc 400

 agagcaggac ttggaaagga gcagagccga ggcctctcaa gagctcttgg 450

 ctcagctcaa cagagctgtc caggtcgtcg tgcacacggg tgacatcact 500

 gaggacctgc tgttggactt ccaggtggtg gtgctgactg ctgcaaagct 550

 ggaggagcag ctgaaggtgg gcaccttgtg tcataagcat ggagtttgct 600

 ttctggcggc tgacacccgg ggcctcgtgg ggcagttgtt ctgtgacttt 650

 ggtgaggact tcactgtgca ggaccccaca gaggcagaac ccctgacagc 700

 tgccatccag cacatctccc agggctcccc tggcattctc actctgagga 750

 aaggggccaa tacccactac ttccgtgatg gagacttggt gactttctcg 800

 ggaattgagg gaatggttga gctcaacgac tgtgatcccc ggtctatcca 850

 cgtgcgggag gatgggtccc tggagattgg agacacaaca actttctctc 900

 ggtacttgcg tggtggggct atcactgaag tcaagagacc caagactgtg 950

 agacataagt ccctggacac agccctgctc cagccccatg tggtggccca 1000

 gagctcccag gaagttcacc atgcccactg cctgcatcag gccttctgtg 1050

 cactgcacaa gttccagcac ctccatggcc ggccacccca gccctgggat 1100

 cctgttgatg cagagactgt ggtgggcctg gcccgggacc tggaaccact 1150

 gaagcggaca gaggaagagc cactggaaga gccactggat gaggccctag 1200

 tgcggacagt cgccctaagc agtgcaaggt gtcttgagcc tatggtggca 1250

 tgctgggtca gtagctgccc aggaagtgct gaaggcaatc tccagaagtt 1300

 catgcctctg gaccagtggc tttactttga tgccctcgat tgtcttccgg 1350

 aagatgggga gctccttccc agtcctgagg actgtgccct gagaggcagc 1400

 cgctatgatg ggcaaattgc agtgtttggg gctggttttc aggagaaact 1450

 gagacgccag cactacctcc tggtgggcgc tggtgccatt ggttgtgagc 1500

 tgctcaaagt ctttgcccta gtgggactgg gggccgggaa cagcgggggc 1550

 ttgactgttg ttgacatgga ccacatagag cgctccaatc tcagccgtca 1600

 gttcctcttc aggtcccagg acgttggtag acccaaggca gaggtggctg 1650

 cagcagctgc ccggggcctg aacccagact tacaggtgat cccgctcacc 1700

 tacccactgg atcccaccac agagcacatc tatggggata actttttctc 1750

 ccgtgtggat ggtgtggctg ctgccctgga cagtttccag gcccggcgct 1800

 atgtggctgc tcgttgcacc cactatctga agccactgct ggaggcaggc 1850

 acatcgggca cctggggcag tgctacagta ttcatgccac atgtgactga 1900

 ggcctacaga gcccctgcct cagctgcagc ttctgaggat gccccctacc 1950

 ctgtctgtac cgtgcggtac ttccctagca cagccgagca caccctgcag 2000

 tgggcccggc atgagtttga agaactcttc cgactgtctg cagagaccat 2050

 caaccaccac caacaggcac acacctccct ggcagacatg gatgagccac 2100

 agacactcac cttactgaag ccagtgcttg gggtcctgag agtgcgtcca 2150

 cagaactggc aagactgtgt ggcgtgggct cttggccact ggaaactctg 2200

 ctttcattat ggcatcaaac agctgctgag gcacttccca cctaataaag 2250

 tgcttgagga tggaactccc ttctggtcag gtcccaaaca gtgtccccag 2300

 cccttggagt ttgacaccaa ccaagacaca cacctcctct acgtactggc 2350

 agctgccaac ctgtatgccc agatgcatgg gctgcctggc tcacaggact 2400

 ggactgcact cagggagctg ctgaagctgc tgccacagcc tgacccccaa 2450

 cagatggccc ccatctttgc tagtaatcta gagctggctt cggcttctgc 2500

 tgagtttggc cctgagcagc agaaggaact gaacaaagcc ctggaagtct 2550

 ggagtgtggg ccctcccctg aagcctctga tgtttgagaa ggatgatgac 2600

 agcaacttcc atgtggactt tgtggtagcg gcagctagcc tgagatgtca 2650

 gaactacggg attccaccgg tcaaccgtgc ccagagcaag cgaattgtgg 2700

 gccagattat cccagccatt gccaccacta cagcagctgt ggcaggcctg 2750

 ttgggcctgg agctgtataa ggtggtgagt gggccacggc ctcgtagtgc 2800

 ctttcgccac agctacctac atctggctga aaactacctc atccgctata 2850

 tgccttttgc cccagccatc cagacgttcc atcacctgaa gtggacctct 2900

 tgggaccgtc tgaaggtacc agctgggcag cctgagagga ccctggagtc 2950

 gctgctggct catcttcagg agcagcacgg gttgagggtg aggatcctgc 3000

 tgcacggctc agccctgctc tatgcggccg gatggtcacc tgaaaagcag 3050

 gcccagcacc tgcccctcag ggtgacagaa ctggttcagc agctgacagg 3100

 ccaggcacct gctcctgggc agcgggtgtt ggtgctagag ctgagctgtg 3150

 agggtgacga cgaggacact gccttcccac ctctgcacta tgagctgtga 3200

 caaggcagcc accctgtcac ctagctcaat ggagccccgg atcccaagcc 3250

 ctgcattgta agcccacagt aggcactcaa taattgcttg ttaaaggaag 3300

 g 3301

<210> 846
<211> 1011
<212> PRT
<213> Homo sapien

<400> 846
 Met Asp Ala Leu Asp Ala Ser Lys Leu Leu Asp Glu Glu Leu Tyr
   1               5                  10                  15

 Ser Arg Gln Leu Tyr Val Leu Gly Ser Pro Ala Met Gln Arg Ile
                  20                  25                  30

 Gln Gly Ala Arg Val Leu Val Ser Gly Leu Gln Gly Leu Gly Ala
                  35                  40                  45

 Glu Val Ala Lys Asn Leu Val Leu Met Gly Val Gly Ser Leu Thr
                  50                  55                  60

 Leu His Asp Pro His Pro Thr Cys Trp Ser Asp Leu Ala Ala Gln
                  65                  70                  75

 Phe Leu Leu Ser Glu Gln Asp Leu Glu Arg Ser Arg Ala Glu Ala
                  80                  85                  90

 Ser Gln Glu Leu Leu Ala Gln Leu Asn Arg Ala Val Gln Val Val
                  95                 100                 105

 Val His Thr Gly Asp Ile Thr Glu Asp Leu Leu Leu Asp Phe Gln
                 110                 115                 120

 Val Val Val Leu Thr Ala Ala Lys Leu Glu Glu Gln Leu Lys Val
                 125                 130                 135

 Gly Thr Leu Cys His Lys His Gly Val Cys Phe Leu Ala Ala Asp
                 140                 145                 150

 Thr Arg Gly Leu Val Gly Gln Leu Phe Cys Asp Phe Gly Glu Asp
                 155                 160                 165

 Phe Thr Val Gln Asp Pro Thr Glu Ala Glu Pro Leu Thr Ala Ala
                 170                 175                 180

 Ile Gln His Ile Ser Gln Gly Ser Pro Gly Ile Leu Thr Leu Arg
                 185                 190                 195

 Lys Gly Ala Asn Thr His Tyr Phe Arg Asp Gly Asp Leu Val Thr
                 200                 205                 210

 Phe Ser Gly Ile Glu Gly Met Val Glu Leu Asn Asp Cys Asp Pro
                 215                 220                 225

 Arg Ser Ile His Val Arg Glu Asp Gly Ser Leu Glu Ile Gly Asp
                 230                 235                 240

 Thr Thr Thr Phe Ser Arg Tyr Leu Arg Gly Gly Ala Ile Thr Glu
                 245                 250                 255

 Val Lys Arg Pro Lys Thr Val Arg His Lys Ser Leu Asp Thr Ala
                 260                 265                 270

 Leu Leu Gln Pro His Val Val Ala Gln Ser Ser Gln Glu Val His
                 275                 280                 285

 His Ala His Cys Leu His Gln Ala Phe Cys Ala Leu His Lys Phe
                 290                 295                 300

 Gln His Leu His Gly Arg Pro Pro Gln Pro Trp Asp Pro Val Asp
                 305                 310                 315

 Ala Glu Thr Val Val Gly Leu Ala Arg Asp Leu Glu Pro Leu Lys
                 320                 325                 330

 Arg Thr Glu Glu Glu Pro Leu Glu Glu Pro Leu Asp Glu Ala Leu
                 335                 340                 345

 Val Arg Thr Val Ala Leu Ser Ser Ala Arg Cys Leu Glu Pro Met
                 350                 355                 360

 Val Ala Cys Trp Val Ser Ser Cys Pro Gly Ser Ala Glu Gly Asn
                 365                 370                 375

 Leu Gln Lys Phe Met Pro Leu Asp Gln Trp Leu Tyr Phe Asp Ala
                 380                 385                 390

 Leu Asp Cys Leu Pro Glu Asp Gly Glu Leu Leu Pro Ser Pro Glu
                 395                 400                 405

 Asp Cys Ala Leu Arg Gly Ser Arg Tyr Asp Gly Gln Ile Ala Val
                 410                 415                 420

 Phe Gly Ala Gly Phe Gln Glu Lys Leu Arg Arg Gln His Tyr Leu
                 425                 430                 435

 Leu Val Gly Ala Gly Ala Ile Gly Cys Glu Leu Leu Lys Val Phe
                 440                 445                 450

 Ala Leu Val Gly Leu Gly Ala Gly Asn Ser Gly Gly Leu Thr Val
                 455                 460                 465

 Val Asp Met Asp His Ile Glu Arg Ser Asn Leu Ser Arg Gln Phe
                 470                 475                 480

 Leu Phe Arg Ser Gln Asp Val Gly Arg Pro Lys Ala Glu Val Ala
                 485                 490                 495

 Ala Ala Ala Ala Arg Gly Leu Asn Pro Asp Leu Gln Val Ile Pro
                 500                 505                 510

 Leu Thr Tyr Pro Leu Asp Pro Thr Thr Glu His Ile Tyr Gly Asp
                 515                 520                 525

 Asn Phe Phe Ser Arg Val Asp Gly Val Ala Ala Ala Leu Asp Ser
                 530                 535                 540

 Phe Gln Ala Arg Arg Tyr Val Ala Ala Arg Cys Thr His Tyr Leu
                 545                 550                 555

 Lys Pro Leu Leu Glu Ala Gly Thr Ser Gly Thr Trp Gly Ser Ala
                 560                 565                 570

 Thr Val Phe Met Pro His Val Thr Glu Ala Tyr Arg Ala Pro Ala
                 575                 580                 585

 Ser Ala Ala Ala Ser Glu Asp Ala Pro Tyr Pro Val Cys Thr Val
                 590                 595                 600

 Arg Tyr Phe Pro Ser Thr Ala Glu His Thr Leu Gln Trp Ala Arg
                 605                 610                 615

 His Glu Phe Glu Glu Leu Phe Arg Leu Ser Ala Glu Thr Ile Asn
                 620                 625                 630

 His His Gln Gln Ala His Thr Ser Leu Ala Asp Met Asp Glu Pro
                 635                 640                 645

 Gln Thr Leu Thr Leu Leu Lys Pro Val Leu Gly Val Leu Arg Val
                 650                 655                 660

 Arg Pro Gln Asn Trp Gln Asp Cys Val Ala Trp Ala Leu Gly His
                 665                 670                 675

 Trp Lys Leu Cys Phe His Tyr Gly Ile Lys Gln Leu Leu Arg His
                 680                 685                 690

 Phe Pro Pro Asn Lys Val Leu Glu Asp Gly Thr Pro Phe Trp Ser
                 695                 700                 705

 Gly Pro Lys Gln Cys Pro Gln Pro Leu Glu Phe Asp Thr Asn Gln
                 710                 715                 720

 Asp Thr His Leu Leu Tyr Val Leu Ala Ala Ala Asn Leu Tyr Ala
                 725                 730                 735

 Gln Met His Gly Leu Pro Gly Ser Gln Asp Trp Thr Ala Leu Arg
                 740                 745                 750

 Glu Leu Leu Lys Leu Leu Pro Gln Pro Asp Pro Gln Gln Met Ala
                 755                 760                 765

 Pro Ile Phe Ala Ser Asn Leu Glu Leu Ala Ser Ala Ser Ala Glu
                 770                 775                 780

 Phe Gly Pro Glu Gln Gln Lys Glu Leu Asn Lys Ala Leu Glu Val
                 785                 790                 795

 Trp Ser Val Gly Pro Pro Leu Lys Pro Leu Met Phe Glu Lys Asp
                 800                 805                 810

 Asp Asp Ser Asn Phe His Val Asp Phe Val Val Ala Ala Ala Ser
                 815                 820                 825

 Leu Arg Cys Gln Asn Tyr Gly Ile Pro Pro Val Asn Arg Ala Gln
                 830                 835                 840

 Ser Lys Arg Ile Val Gly Gln Ile Ile Pro Ala Ile Ala Thr Thr
                 845                 850                 855

 Thr Ala Ala Val Ala Gly Leu Leu Gly Leu Glu Leu Tyr Lys Val
                 860                 865                 870

 Val Ser Gly Pro Arg Pro Arg Ser Ala Phe Arg His Ser Tyr Leu
                 875                 880                 885

 His Leu Ala Glu Asn Tyr Leu Ile Arg Tyr Met Pro Phe Ala Pro
                 890                 895                 900

 Ala Ile Gln Thr Phe His His Leu Lys Trp Thr Ser Trp Asp Arg
                 905                 910                 915

 Leu Lys Val Pro Ala Gly Gln Pro Glu Arg Thr Leu Glu Ser Leu
                 920                 925                 930

 Leu Ala His Leu Gln Glu Gln His Gly Leu Arg Val Arg Ile Leu
                 935                 940                 945

 Leu His Gly Ser Ala Leu Leu Tyr Ala Ala Gly Trp Ser Pro Glu
                 950                 955                 960

 Lys Gln Ala Gln His Leu Pro Leu Arg Val Thr Glu Leu Val Gln
                 965                 970                 975

 Gln Leu Thr Gly Gln Ala Pro Ala Pro Gly Gln Arg Val Leu Val
                 980                 985                 990

 Leu Glu Leu Ser Cys Glu Gly Asp Asp Glu Asp Thr Ala Phe Pro
                 995                1000                1005

 Pro Leu His Tyr Glu Leu
                1010

<210> 847
<211> 2764
<212> DNA
<213> Homo sapien

<400> 847
 ctctaaagct tagagccaag atggcgggat ccaggcaaag gggtctccgg 50

 gccagagttc ggccgctgtt ctgcgccttg ctgctgtcac tcggtcgctt 100

 cgtccggggc gacggcgtgg gaggagaccc cgcggtcgcg ttgccacatc 150

 gccgtttcga gtacaaatac agcttcaagg ggccgcacct ggtgcagagc 200

 gacgggaccg tgcccttctg ggcccacgcg gggaatgcta ttccaagttc 250

 agatcaaatt cgagtagcac catctttaaa aagccaaaga ggctcagtgt 300

 ggacaaagac aaaagcggcc tttgagaact gggaagttga ggtgacattt 350

 cgagtgactg gaagaggtcg aattggagct gatggcctag caatttggta 400

 tgcagaaaat caaggcttgg agggccctgt gtttggatca gctgatctgt 450

 ggaatggtgt tggaatattt tttgattctt ttgacaatga tggaaagaaa 500

 aataatcctg ctatagtaat tataggcaac aatggacaaa tccattatga 550

 ccatcaaaat gacggggcta gtcaagcttt ggcaagttgc cagagggact 600

 tccgcaacaa accctatcct gtccgagcaa agattaccta ttaccagaac 650

 acactgacag taatgatcaa taatggcttt acaccagata aaaatgatta 700

 tgaattttgt gccaaagtgg aaaatatgat tatccctgca caagggcatt 750

 ttggaatatc tgctgcaact ggaggtcttg cagatgacca tgatgtcctt 800

 tcttttctga ctttccagtt gactgaacct ggaaaagagc cgcccacacc 850

 agataaagaa atttcggaaa aggaaaaaga aaagtatcag gaggaatttg 900

 agcactttca acaagaattg gataaaaaaa aagaggaatt ccagaagggc 950

 caccccgacc tccaagggca gcctgcggag gaaatatttg agagtgtagg 1000

 agatcgagag ctaagacaag tctttgaagg acagaatcgt attcatcttg 1050

 aaatcaagca gctgaaccgg cagttagata tgattcttga tgaacagaga 1100

 agatatgtct cttccttaac agaggaaatc tctaaaagag gagcaggaat 1150

 gcctgggcag catgggcaga ttactcaaca agaactggat actgttgtga 1200

 aaactcagca tgagattctg agacaagtaa atgaaatgaa aaattccatg 1250

 agtgaaaccg tcagactggt cagtggaatg cagcaccctg gctctgctgg 1300

 aggcgtctat gagacaacac agcacttcat tgacatcaaa gagcacctgc 1350

 acatagtaaa gagggacata gataacttag tgcagcgaaa tatgccatca 1400

 aatgaaaagc cgaaatgccc agaactacca ccatttccat catgtttgtc 1450

 tacggtccac ttcattatat ttgttgtggt gcaaactgta ttattcattg 1500

 gttatatcat gtataggtct cagcaagaag cagctgccaa aaaattcttt 1550

 tgactaccat tttcctgtgt acttcatcta tttgtgtaca aaatgatgtc 1600

 gttttgaggg aatttaagta tttaaattgc ttcatagtct aaattattaa 1650

 ttttcttaat aaaataactg tttaaacatt gatttgcagt taagaataaa 1700

 ccttaaagca aagacaacca cattttaatt tgttcacagt atgtaaatct 1750

 gtctaaattt cagtgaattt ctggtcagta tgatgcagcc tctgagcaga 1800

 tattgaccag taagagggta aataaagtgg gggcaacccc tggatatgaa 1850

 tgttaccccc taagtctcca atattgcagg tttccctgta taacgtaaac 1900

 acacttgccc tcatgcctcc cagaatatga ggtctaatta agaagtccca 1950

 tcaggtttat tttgtaacca aagtcttttt tagaggtcag acttcctaat 2000

 caaaggcctg ggcctgcagt cctttcatct taatgcaact tcctttgaaa 2050

 tcaaagaata ttttgtctga gagctttaag gatctggtaa tagacttcaa 2100

 aatgttaagt gaaatttttt ttcctctatt tatcaatgat atatttcact 2150

 tttaaaggaa attttggagg aaaatatagc tgctttttgc ctaaaaaacc 2200

 ttgtgggtgg aaatattcct ctgagaatgg cttttatagg tattttgcct 2250

 ggtaatgtat tcattcatga ttgcccatat tcttgaatgt ttcttcattc 2300

 caatggggtc aggtcaatat tatgaaaata atttttatat ttatatttgt 2350

 aactaagaat ttatttctcc ctttactaca cgatgtaaat tcacgtcaaa 2400

 ttcgatgatc tgaggattta aattcacaaa acctgccact acattctggt 2450

 ttacattagt tacttcatgc tggctggggt tagtgaccat ttgcatactc 2500

 ttttaaatca aggaggctgt agtagaggca gttttaagat tcttgaaggc 2550

 aaaatttgaa aaacagtgaa tacttctaat tgtttccttt tagtgccaga 2600

 actaagacat tgtgaagcac ttgttagtaa acttaacctt gaaatgtcag 2650

 actggaagga gtttttatgt ctttgtgcat acttctgggt attacagaaa 2700

 cagtctgtaa ataacatttt aagatgcaaa tttaattctg ttcacagctg 2750

 atttatactg attt 2764

<210> 848
<211> 510
<212> PRT
<213> Homo sapien

<400> 848
 Met Ala Gly Ser Arg Gln Arg Gly Leu Arg Ala Arg Val Arg Pro
   1               5                  10                  15

 Leu Phe Cys Ala Leu Leu Leu Ser Leu Gly Arg Phe Val Arg Gly
                  20                  25                  30

 Asp Gly Val Gly Gly Asp Pro Ala Val Ala Leu Pro His Arg Arg
                  35                  40                  45

 Phe Glu Tyr Lys Tyr Ser Phe Lys Gly Pro His Leu Val Gln Ser
                  50                  55                  60

 Asp Gly Thr Val Pro Phe Trp Ala His Ala Gly Asn Ala Ile Pro
                  65                  70                  75

 Ser Ser Asp Gln Ile Arg Val Ala Pro Ser Leu Lys Ser Gln Arg
                  80                  85                  90

 Gly Ser Val Trp Thr Lys Thr Lys Ala Ala Phe Glu Asn Trp Glu
                  95                 100                 105

 Val Glu Val Thr Phe Arg Val Thr Gly Arg Gly Arg Ile Gly Ala
                 110                 115                 120

 Asp Gly Leu Ala Ile Trp Tyr Ala Glu Asn Gln Gly Leu Glu Gly
                 125                 130                 135

 Pro Val Phe Gly Ser Ala Asp Leu Trp Asn Gly Val Gly Ile Phe
                 140                 145                 150

 Phe Asp Ser Phe Asp Asn Asp Gly Lys Lys Asn Asn Pro Ala Ile
                 155                 160                 165

 Val Ile Ile Gly Asn Asn Gly Gln Ile His Tyr Asp His Gln Asn
                 170                 175                 180

 Asp Gly Ala Ser Gln Ala Leu Ala Ser Cys Gln Arg Asp Phe Arg
                 185                 190                 195

 Asn Lys Pro Tyr Pro Val Arg Ala Lys Ile Thr Tyr Tyr Gln Asn
                 200                 205                 210

 Thr Leu Thr Val Met Ile Asn Asn Gly Phe Thr Pro Asp Lys Asn
                 215                 220                 225

 Asp Tyr Glu Phe Cys Ala Lys Val Glu Asn Met Ile Ile Pro Ala
                 230                 235                 240

 Gln Gly His Phe Gly Ile Ser Ala Ala Thr Gly Gly Leu Ala Asp
                 245                 250                 255

 Asp His Asp Val Leu Ser Phe Leu Thr Phe Gln Leu Thr Glu Pro
                 260                 265                 270

 Gly Lys Glu Pro Pro Thr Pro Asp Lys Glu Ile Ser Glu Lys Glu
                 275                 280                 285

 Lys Glu Lys Tyr Gln Glu Glu Phe Glu His Phe Gln Gln Glu Leu
                 290                 295                 300

 Asp Lys Lys Lys Glu Glu Phe Gln Lys Gly His Pro Asp Leu Gln
                 305                 310                 315

 Gly Gln Pro Ala Glu Glu Ile Phe Glu Ser Val Gly Asp Arg Glu
                 320                 325                 330

 Leu Arg Gln Val Phe Glu Gly Gln Asn Arg Ile His Leu Glu Ile
                 335                 340                 345

 Lys Gln Leu Asn Arg Gln Leu Asp Met Ile Leu Asp Glu Gln Arg
                 350                 355                 360

 Arg Tyr Val Ser Ser Leu Thr Glu Glu Ile Ser Lys Arg Gly Ala
                 365                 370                 375

 Gly Met Pro Gly Gln His Gly Gln Ile Thr Gln Gln Glu Leu Asp
                 380                 385                 390

 Thr Val Val Lys Thr Gln His Glu Ile Leu Arg Gln Val Asn Glu
                 395                 400                 405

 Met Lys Asn Ser Met Ser Glu Thr Val Arg Leu Val Ser Gly Met
                 410                 415                 420

 Gln His Pro Gly Ser Ala Gly Gly Val Tyr Glu Thr Thr Gln His
                 425                 430                 435

 Phe Ile Asp Ile Lys Glu His Leu His Ile Val Lys Arg Asp Ile
                 440                 445                 450

 Asp Asn Leu Val Gln Arg Asn Met Pro Ser Asn Glu Lys Pro Lys
                 455                 460                 465

 Cys Pro Glu Leu Pro Pro Phe Pro Ser Cys Leu Ser Thr Val His
                 470                 475                 480

 Phe Ile Ile Phe Val Val Val Gln Thr Val Leu Phe Ile Gly Tyr
                 485                 490                 495

 Ile Met Tyr Arg Ser Gln Gln Glu Ala Ala Ala Lys Lys Phe Phe
                 500                 505                 510

<210> 849
<211> 2764
<212> DNA
<213> Homo sapien

<400> 849
 ctctaaagct tagagccaag atggcgggat ccaggcaaag gggtctccgg 50

 gccagagttc ggccgctgtt ctgcgccttg ctgctgtcac tcggtcgctt 100

 cgtccggggc gacggcgtgg gaggagaccc cgcggtcgcg ttgccacatc 150

 gccgtttcga gtacaaatac agcttcaagg ggccgcacct ggtgcagagc 200

 gacgggaccg tgcccttctg ggcccacgcg gggaatgcta ttccaagttc 250

 agatcaaatt cgagtagcac catctttaaa aagccaaaga ggctcagtgt 300

 ggacaaagac aaaagcggcc tttgagaact gggaagttga ggtgacattt 350

 cgagtgactg gaagaggtcg aattggagct gatggcctag caatttggta 400

 tgcagaaaat caaggcttgg agggccctgt gtttggatca gctgatctgt 450

 ggaatggtgt tggaatattt tttgattctt ttgacaatga tggaaagaaa 500

 aataatcctg ctatagtaat tataggcaac aatggacaaa tccattatga 550

 ccatcaaaat gacggggcta gtcaagcttt ggcaagttgc cagagggact 600

 tccgcaacaa accctatcct gtccgagcaa agattaccta ttaccagaac 650

 acactgacag taatgatcaa taatggcttt acaccagata aaaatgatta 700

 tgaattttgt gccaaagtgg aaaatatgat tatccctgca caagggcatt 750

 ttggaatatc tgctgcaact ggaggtcttg cagatgacca tgatgtcctt 800

 tcttttctga ctttccagtt gactgaacct ggaaaagagc cgcccacacc 850

 agataaagaa atttcggaaa aggaaaaaga aaagtatcag gaggaatttg 900

 agcactttca acaagaattg gataaaaaaa aagaggaatt ccagaagggc 950

 caccccgacc tccaagggca gcctgcggag gaaatatttg agagtgtagg 1000

 agatcgagag ctaagacaag tctttgaagg acagaatcgt attcatcttg 1050

 aaatcaagca gctgaaccgg cagttagata tgattcttga tgaacagaga 1100

 agatatgtct cttccttaac agaggaaatc tctaaaagag gagcaggaat 1150

 gcctgggcag catgggcaga ttactcaaca agaactggat actgttgtga 1200

 aaactcagca tgagattctg agacaagtaa atgaaatgaa aaattccatg 1250

 agtgaaaccg tcagactggt cagtggaatg cagcaccctg gctctgctgg 1300

 aggcgtctat gagacaacac agcacttcat tgacatcaaa gagcacctgc 1350

 acatagtaaa gagggacata gataacttag tgcagcgaaa tatgccatca 1400

 aatgaaaagc cgaaatgccc agaactacca ccatttccat catgtttgtc 1450

 tacggtccac ttcattatat ttgttgtggt gcaaactgta ttattcattg 1500

 gttatatcat gtataggtct cagcaagaag cagctgccaa aaaattcttt 1550

 tgactaccat tttcctgtgt acttcatcta tttgtgtaca aaatgatgtc 1600

 gttttgaggg aatttaagta tttaaattgc ttcatagtct aaattattaa 1650

 ttttcttaat aaaataactg tttaaacatt gatttgcagt taagaataaa 1700

 ccttaaagca aagacaacca cattttaatt tgttcacagt atgtaaatct 1750

 gtctaaattt cagtgaattt ctggtcagta tgatgcagcc tctgagcaga 1800

 tattgaccag taagagggta aataaagtgg gggcaacccc tggatatgaa 1850

 tgttaccccc taagtctcca atattgcagg tttccctgta taacgtaaac 1900

 acacttgccc tcatgcctcc cagaatatga ggtctaatta agaagtccca 1950

 tcaggtttat tttgtaacca aagtcttttt tagaggtcag acttcctaat 2000

 caaaggcctg ggcctgcagt cctttcatct taatgcaact tcctttgaaa 2050

 tcaaagaata ttttgtctga gagctttaag gatctggtaa tagacttcaa 2100

 aatgttaagt gaaatttttt ttcctctatt tatcaatgat atatttcact 2150

 tttaaaggaa attttggagg aaaatatagc tgctttttgc ctaaaaaacc 2200

 ttgtgggtgg aaatattcct ctgagaatgg cttttatagg tattttgcct 2250

 ggtaatgtat tcattcatga ttgcccatat tcttgaatgt ttcttcattc 2300

 caatggggtc aggtcaatat tatgaaaata atttttatat ttatatttgt 2350

 aactaagaat ttatttctcc ctttactaca cgatgtaaat tcacgtcaaa 2400

 ttcgatgatc tgaggattta aattcacaaa acctgccact acattctggt 2450

 ttacattagt tacttcatgc tggctggggt tagtgaccat ttgcatactc 2500

 ttttaaatca aggaggctgt agtagaggca gttttaagat tcttgaaggc 2550

 aaaatttgaa aaacagtgaa tacttctaat tgtttccttt tagtgccaga 2600

 actaagacat tgtgaagcac ttgttagtaa acttaacctt gaaatgtcag 2650

 actggaagga gtttttatgt ctttgtgcat acttctgggt attacagaaa 2700

 cagtctgtaa ataacatttt aagatgcaaa tttaattctg ttcacagctg 2750

 atttatactg attt 2764

<210> 850
<211> 510
<212> PRT
<213> Homo sapien

<400> 850
 Met Ala Gly Ser Arg Gln Arg Gly Leu Arg Ala Arg Val Arg Pro
   1               5                  10                  15

 Leu Phe Cys Ala Leu Leu Leu Ser Leu Gly Arg Phe Val Arg Gly
                  20                  25                  30

 Asp Gly Val Gly Gly Asp Pro Ala Val Ala Leu Pro His Arg Arg
                  35                  40                  45

 Phe Glu Tyr Lys Tyr Ser Phe Lys Gly Pro His Leu Val Gln Ser
                  50                  55                  60

 Asp Gly Thr Val Pro Phe Trp Ala His Ala Gly Asn Ala Ile Pro
                  65                  70                  75

 Ser Ser Asp Gln Ile Arg Val Ala Pro Ser Leu Lys Ser Gln Arg
                  80                  85                  90

 Gly Ser Val Trp Thr Lys Thr Lys Ala Ala Phe Glu Asn Trp Glu
                  95                 100                 105

 Val Glu Val Thr Phe Arg Val Thr Gly Arg Gly Arg Ile Gly Ala
                 110                 115                 120

 Asp Gly Leu Ala Ile Trp Tyr Ala Glu Asn Gln Gly Leu Glu Gly
                 125                 130                 135

 Pro Val Phe Gly Ser Ala Asp Leu Trp Asn Gly Val Gly Ile Phe
                 140                 145                 150

 Phe Asp Ser Phe Asp Asn Asp Gly Lys Lys Asn Asn Pro Ala Ile
                 155                 160                 165

 Val Ile Ile Gly Asn Asn Gly Gln Ile His Tyr Asp His Gln Asn
                 170                 175                 180

 Asp Gly Ala Ser Gln Ala Leu Ala Ser Cys Gln Arg Asp Phe Arg
                 185                 190                 195

 Asn Lys Pro Tyr Pro Val Arg Ala Lys Ile Thr Tyr Tyr Gln Asn
                 200                 205                 210

 Thr Leu Thr Val Met Ile Asn Asn Gly Phe Thr Pro Asp Lys Asn
                 215                 220                 225

 Asp Tyr Glu Phe Cys Ala Lys Val Glu Asn Met Ile Ile Pro Ala
                 230                 235                 240

 Gln Gly His Phe Gly Ile Ser Ala Ala Thr Gly Gly Leu Ala Asp
                 245                 250                 255

 Asp His Asp Val Leu Ser Phe Leu Thr Phe Gln Leu Thr Glu Pro
                 260                 265                 270

 Gly Lys Glu Pro Pro Thr Pro Asp Lys Glu Ile Ser Glu Lys Glu
                 275                 280                 285

 Lys Glu Lys Tyr Gln Glu Glu Phe Glu His Phe Gln Gln Glu Leu
                 290                 295                 300

 Asp Lys Lys Lys Glu Glu Phe Gln Lys Gly His Pro Asp Leu Gln
                 305                 310                 315

 Gly Gln Pro Ala Glu Glu Ile Phe Glu Ser Val Gly Asp Arg Glu
                 320                 325                 330

 Leu Arg Gln Val Phe Glu Gly Gln Asn Arg Ile His Leu Glu Ile
                 335                 340                 345

 Lys Gln Leu Asn Arg Gln Leu Asp Met Ile Leu Asp Glu Gln Arg
                 350                 355                 360

 Arg Tyr Val Ser Ser Leu Thr Glu Glu Ile Ser Lys Arg Gly Ala
                 365                 370                 375

 Gly Met Pro Gly Gln His Gly Gln Ile Thr Gln Gln Glu Leu Asp
                 380                 385                 390

 Thr Val Val Lys Thr Gln His Glu Ile Leu Arg Gln Val Asn Glu
                 395                 400                 405

 Met Lys Asn Ser Met Ser Glu Thr Val Arg Leu Val Ser Gly Met
                 410                 415                 420

 Gln His Pro Gly Ser Ala Gly Gly Val Tyr Glu Thr Thr Gln His
                 425                 430                 435

 Phe Ile Asp Ile Lys Glu His Leu His Ile Val Lys Arg Asp Ile
                 440                 445                 450

 Asp Asn Leu Val Gln Arg Asn Met Pro Ser Asn Glu Lys Pro Lys
                 455                 460                 465

 Cys Pro Glu Leu Pro Pro Phe Pro Ser Cys Leu Ser Thr Val His
                 470                 475                 480

 Phe Ile Ile Phe Val Val Val Gln Thr Val Leu Phe Ile Gly Tyr
                 485                 490                 495

 Ile Met Tyr Arg Ser Gln Gln Glu Ala Ala Ala Lys Lys Phe Phe
                 500                 505                 510

<210> 851
<211> 2156
<212> DNA
<213> Homo sapien

<400> 851
 ggaggccagt gcgcggccgc ggtgctctac cggcgtgtcg ctccgcccca 50

 gggagagccg gcgctaccat ggaggagtac catcgccact gcgacgaggt 100

 tggcttcaat gctgaggaag cccacaatat tgtcaaagag tgtgtagatg 150

 gggttttagg tggtgaagat tataatcaca acaacatcaa ccagtggact 200

 gcaagcatag tggaacaatc cttaacacac ctggttaagt tgggaaaagc 250

 ctataaatat attgtgacct gtgcagtggt ccagaagagc gcatatggct 300

 ttcacacagc cagctcctgt ttttgggata ccacatctga tggaacctgt 350

 accgtaagat gggagaaccg gaccatgaac tgtattgtca acgtttttgc 400

 cattgctatt gttctttaac tgactaaaaa tgttgggcta aagccattaa 450

 cttaagaatt tgtcagtgta tcctttccaa aaagagtaat agttgtttac 500

 tagtgtgcta gatgaaaagc gtgcaatatg ctttaaagct atcaacaaaa 550

 actgaatatt ataagcaagc aatatcatag taattggcag attagctcat 600

 attctataca gcatcgttta aataggaaaa atttaatgct agcaaaaaat 650

 aaatttagaa tatggcatga catgaaaata caatcttata tttacaccag 700

 cttttcacta atattttgta cctaaggtga tggggaactc cattcagata 750

 ataaaattct ctttcagcta gagaagttaa caggaataaa tatatgaaca 800

 aaaaagctgc aaggataaat gtggagaaaa tgatgagaat tagctaacat 850

 ttttaagttt ttttaaactt tcttcccctc agttgtactt aatatttagt 900

 ggaaagtaat aattttttta ttttctatca actaatagta tagtaacaac 950

 tatgattaac ttgtttactt tttctgagga ttagtaaatc aatttttttt 1000

 aatttcaaat tttggattta cacttgaggg taaattaaat ctggtaaact 1050

 gaatttccta gttaaataaa attagttgca gtatatgatg aacagtgtat 1100

 gactcaaaca gctgccttac aattcactca ttccatgtgg aacaaacatt 1150

 tatcagatgc ctattatggg catatgtctc tgctaagcac catagttgtc 1200

 aatgtgctgt gcaaatgcta agttcctttt agcaattgtt cagttggaag 1250

 acgtattaat atttggggaa ggaaaagaaa gtagttgttt tacaagggag 1300

 gaaaaaagtg aatctggtta cacatatgga agtaagcaaa atgaaaagca 1350

 cttattgctt tctgacagaa ttatagatgt aattttaaga gttgctccta 1400

 gcaagttaaa agtgcatata aaatatgcaa ctcttagtta aaggccttat 1450

 tatcagtctt acctatacaa gtagtaaatt ttgtcattgc tttagttaca 1500

 accatctgta aataacttaa aagacttatt atgtggggtt caaattgagt 1550

 ggaataaagt atagattaaa agtatacaat ccttagcacg ttatctcagg 1600

 gcttatgaaa tgtaattaaa tttattaaga aaatagatga aaaattaggg 1650

 tacacagctg gccaccaaat gcgaagtcaa tctgctactt aaccctgaaa 1700

 acaaaatcag ttttgcatat taccactaac actaatacat atagagagcg 1750

 gaaccataac tcattgaatt ttggagagga ataagcttag cgttaatatt 1800

 gacaatatta aggcaatatt cttgtaggaa tactatgtgc atgtttgata 1850

 ttttgccaaa taacaataat taataattgt tcaatgttta agaataatat 1900

 taacaaaata aaggagttta atgcagtgat ctttgttttt ggcacatcaa 1950

 aaattctcag tcattattca tgtttctttt atgctgctgg cttttgtgcc 2000

 ctggaagatc ataatagtga ccaaaatata catgcagact tgttttttat 2050

 tattgttgtt taagcataat ttaagaaaaa aaatttttac ctggtgaact 2100

 tgctatctgc tctgtttcta gttaaaatat aataaatatt atcttcctgt 2150

 gctgta 2156

<210> 852
<211> 116
<212> PRT
<213> Homo sapien

<400> 852
 Met Glu Glu Tyr His Arg His Cys Asp Glu Val Gly Phe Asn Ala
   1               5                  10                  15

 Glu Glu Ala His Asn Ile Val Lys Glu Cys Val Asp Gly Val Leu
                  20                  25                  30

 Gly Gly Glu Asp Tyr Asn His Asn Asn Ile Asn Gln Trp Thr Ala
                  35                  40                  45

 Ser Ile Val Glu Gln Ser Leu Thr His Leu Val Lys Leu Gly Lys
                  50                  55                  60

 Ala Tyr Lys Tyr Ile Val Thr Cys Ala Val Val Gln Lys Ser Ala
                  65                  70                  75

 Tyr Gly Phe His Thr Ala Ser Ser Cys Phe Trp Asp Thr Thr Ser
                  80                  85                  90

 Asp Gly Thr Cys Thr Val Arg Trp Glu Asn Arg Thr Met Asn Cys
                  95                 100                 105

 Ile Val Asn Val Phe Ala Ile Ala Ile Val Leu
                 110                 115

<210> 853
<211> 2076
<212> DNA
<213> Homo sapien

<400> 853
 acattctttc agacccggcc cgctgcgggg cgttcctggg gggtagcctc 50

 aaggccagcg gggttccttc ggctgcgttt ctgtgggagg ccctgaaacg 100

 cgcggagctt ccctctgcct ccaggctttc ccagcgagag tgaaattaaa 150

 cttgaaactc ggatcaactg gcagtcgttg ttggtagaac gccctaagga 200

 cccctccccg cgggacggag ggaggactcg ggacagggaa ttggccctgg 250

 gagaaaacgc gcggggggcg tccgagacgc cccgtgaaag ccgtgccgac 300

 ccttgggagg actgacaggt ctagagacac gcgctgtctg ttgtggtggg 350

 cctcccggga ataagtgagg ggctctgtgt ttcgaggatg gttctagcgc 400

 agagccgggt gtctgccggg gtgggctccc cgcattgttc gggctccggc 450

 gggggcggct ctgattcctt tccatggccc gcctcccacc ccgggaatcc 500

 ccagtgctcc ttttccacgg cttttctggc gtccccccga ctctcccgcg 550

 gcactttggc ctaccttccc ccagcgccgt ggtcctccct ggcgaccccc 600

 tctgcgctcc tggggtcctc ctgcgccccc cctcctccac cggcgcgctg 650

 cccacagccg cgtgccctct ccccggagct ggggaccaag gctgggcccc 700

 gccggccgca tcggtgggaa cttccgcggt ccccatccca gggcgcacag 750

 ggtccagctc ctcggcgccg actcctggaa acaatgaaag gtattgttgc 800

 agcatctggc agtgagactg aggatgagga cagcatggac attcccttgg 850

 acctttcttc atccgctggc tcaggcaaga gaaggagaag gggcaaccta 900

 cccaaggagt ctgtgcagat tcttcgggat tggctgtatg agcaccgtta 950

 caatgcctat ccttcagagc aagaaaaagc gttgctgtcc cagcaaacac 1000

 acctgtctac gctacaggtc tgtaactggt tcatcaacgc ccgccgcagg 1050

 ctcctccctg acatgctgag aaaggatggc aaagatccaa atcagttcac 1100

 aatttcccgc cgtggggcca agatttctga aacgagctct gtggagtccg 1150

 tgatgggcat caaaaacttc atgccagctc tagaggagac cccatttcat 1200

 tcctgtacag ctgggccaaa cccaacccta gggaggccac tgtctcctaa 1250

 gccgtcatcc ccgggatcag ttttggctcg tccatcagtg atctgccata 1300

 ccactgtgac tgcattgaaa gatgtccctt tctctctctg ccagtcggtc 1350

 ggtgtgggac aaaacacaga tatacagcag atagcggcca aaaacttcac 1400

 agacacctct ctcatgtacc cagaggacac ttgtaaatct ggaccaagta 1450

 cgaatacaca gagtggtctt ttcaacactc ctccccctac tccaccggac 1500

 ctcaaccagg acttcagtgg atttcagctt ctagtggatg ttgcactcaa 1550

 acgggctgca gagatggagc ttcaggcaaa acttacagct taacccattt 1600

 tcaagcaaaa cagttctcag aaatgtcatg attgccgggg tgaaggcaag 1650

 agatgaattg cattatttta tatatttttt attaatattt gcacatggga 1700

 ttgctaaaac agcttcctgt tactgagatg tcttcaatgg aatacagtca 1750

 ttccaagaac tataaactta aagctactgt agaaacaaag ggttttcttt 1800

 tttaaatgtt tcttggtaga ttattcataa tgtgagatgg ttcccaatat 1850

 catgtgattt tttttttcct ccccttccct ttttttgtta ttttttcaga 1900

 ctgtgcaata cttagagaac ctatagcatc ttctcattcc catgtggaac 1950

 aggatgccca catactgtct aattaataaa ttttccattt tttttcaaac 2000

 aagtatgaat ctagttggtt gatgcctttt ttttcatgac ataataaagt 2050

 attttcttta aaaaaaaaaa aaaaaa 2076

<210> 854
<211> 401
<212> PRT
<213> Homo sapien

<400> 854
 Met Val Leu Ala Gln Ser Arg Val Ser Ala Gly Val Gly Ser Pro
   1               5                  10                  15

 His Cys Ser Gly Ser Gly Gly Gly Gly Ser Asp Ser Phe Pro Trp
                  20                  25                  30

 Pro Ala Ser His Pro Gly Asn Pro Gln Cys Ser Phe Ser Thr Ala
                  35                  40                  45

 Phe Leu Ala Ser Pro Arg Leu Ser Arg Gly Thr Leu Ala Tyr Leu
                  50                  55                  60

 Pro Pro Ala Pro Trp Ser Ser Leu Ala Thr Pro Ser Ala Leu Leu
                  65                  70                  75

 Gly Ser Ser Cys Ala Pro Pro Pro Pro Pro Ala Arg Cys Pro Gln
                  80                  85                  90

 Pro Arg Ala Leu Ser Gln Glu Leu Gly Thr Lys Ala Gly Pro Arg
                  95                 100                 105

 Arg Pro His Arg Trp Glu Leu Pro Arg Ser Pro Ser Gln Gly Ala
                 110                 115                 120

 Gln Gly Pro Ala Pro Arg Arg Arg Leu Leu Glu Thr Met Lys Gly
                 125                 130                 135

 Ile Val Ala Ala Ser Gly Ser Glu Thr Glu Asp Glu Asp Ser Met
                 140                 145                 150

 Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly Lys Arg
                 155                 160                 165

 Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu Arg
                 170                 175                 180

 Asp Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu Gln
                 185                 190                 195

 Glu Lys Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu Gln
                 200                 205                 210

 Val Cys Asn Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro Asp
                 215                 220                 225

 Met Leu Arg Lys Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile Ser
                 230                 235                 240

 Arg Arg Gly Ala Lys Ile Ser Glu Thr Ser Ser Val Glu Ser Val
                 245                 250                 255

 Met Gly Ile Lys Asn Phe Met Pro Ala Leu Glu Glu Thr Pro Phe
                 260                 265                 270

 His Ser Cys Thr Ala Gly Pro Asn Pro Thr Leu Gly Arg Pro Leu
                 275                 280                 285

 Ser Pro Lys Pro Ser Ser Pro Gly Ser Val Leu Ala Arg Pro Ser
                 290                 295                 300

 Val Ile Cys His Thr Thr Val Thr Ala Leu Lys Asp Val Pro Phe
                 305                 310                 315

 Ser Leu Cys Gln Ser Val Gly Val Gly Gln Asn Thr Asp Ile Gln
                 320                 325                 330

 Gln Ile Ala Ala Lys Asn Phe Thr Asp Thr Ser Leu Met Tyr Pro
                 335                 340                 345

 Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr Asn Thr Gln Ser Gly
                 350                 355                 360

 Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp Leu Asn Gln Asp
                 365                 370                 375

 Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu Lys Arg Ala
                 380                 385                 390

 Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala
                 395                 400

<210> 855
<211> 500
<212> DNA
<213> Homo sapien

<400> 855
 gctctcagag gcagcgtgcg ggtgtgctct ttgtgaaatt ccaccatggc 50

 gtaccgtggc cagggtcaga aagtgcagaa ggttatggtg cagcccatca 100

 acctcatctt cagatactta caaaatagat cgcggattca ggtgtggctc 150

 tatgagcaag tgaatatgcg gatagaaggc tgtatcattg gttttgatga 200

 gtatatgaac cttgtattag atgatgcaga agagattcat tctaaaacaa 250

 agtcaagaaa acaactgggt cggatcatgc taaaaggaga taatattact 300

 ctgctacaaa gtgtctccaa ctagaaatga tcaatgaagt gagaaattgt 350

 tgagaaggat acagtttgtt tttagatgtc ctttgtccaa tgtgaacatt 400

 tattcatatt gttttgatta ccctcgtgtt actacaagat ggcaataaat 450

 actatgggat tgtttgtatt aaaaaattta cattgcttct taaaaaaaaa 500

<210> 856
<211> 92
<212> PRT
<213> Homo sapien

<400> 856
 Met Ala Tyr Arg Gly Gln Gly Gln Lys Val Gln Lys Val Met Val
   1               5                  10                  15

 Gln Pro Ile Asn Leu Ile Phe Arg Tyr Leu Gln Asn Arg Ser Arg
                  20                  25                  30

 Ile Gln Val Trp Leu Tyr Glu Gln Val Asn Met Arg Ile Glu Gly
                  35                  40                  45

 Cys Ile Ile Gly Phe Asp Glu Tyr Met Asn Leu Val Leu Asp Asp
                  50                  55                  60

 Ala Glu Glu Ile His Ser Lys Thr Lys Ser Arg Lys Gln Leu Gly
                  65                  70                  75

 Arg Ile Met Leu Lys Gly Asp Asn Ile Thr Leu Leu Gln Ser Val
                  80                  85                  90

 Ser Asn


<210> 857
<211> 4906
<212> DNA
<213> Homo sapien

<400> 857
 gttgctgtcg ccgttgctgt cggccgaggc caccaagagg caacgggcgg 50

 caggttgcag tggaggggcc tccgctcccc tcggtggtgt gtgggtcctg 100

 ggggtgcctg ccggcccagc cgaggaggcc cacgcccacc atggtcccct 150

 gctggaacca tggcaacatc acccgctcca aggcggagga gctgctttcc 200

 aggacaggca aggacgggag cttcctcgtg cgtgccagcg agtccatctc 250

 ccgggcatac gcgctctgcg tgctgtatcg gaattgcgtt tacacttaca 300

 gaattctgcc caatgaagat gataaattca ctgttcaggc atccgaaggc 350

 gtctccatga ggttcttcac caagctggac cagctcatcg agttttacaa 400

 gaaggaaaac atggggctgg tgacccatct gcaataccct gtgccgctgg 450

 aggaagagga cacaggcgac gaccctgagg aggacacaga aagtgtcgtg 500

 tctccacccg agctgccccc aagaaacatc ccgctgactg ccagctcctg 550

 tgaggccaag gaggttcctt tttcaaacga gaatccccga gcgaccgaga 600

 ccagccggcc gagcctctcc gagacattgt tccagcgact gcaaagcatg 650

 gacaccagtg ggcttccaga agagcatctt aaggccatcc aagattattt 700

 aagcactcag ctcgcccagg actctgaatt tgtgaagaca gggtccagca 750

 gtcttcctca cctgaagaaa ctgaccacac tgctctgcaa ggagctctat 800

 ggagaagtca tccggaccct cccatccctg gagtctctgc agaggttatt 850

 tgaccagcag ctctccccgg gcctccgtcc acgtcctcag gttcctggtg 900

 aggccaatcc catcaacatg gtgtccaagc tcagccaact gacaagcctg 950

 ttgtcgtcca ttgaagacaa ggtcaaggcc ttgctgcacg agggtcctga 1000

 gtctccgcac cggccctccc ttatccctcc agtcaccttt gaggtgaagg 1050

 cagagtctct ggggattcct cagaaaatgc agctcaaagt cgacgttgag 1100

 tctgggaaac tgatcattaa gaagtccaag gatggttctg aggacaagtt 1150

 ctacagccac aagaaaatcc tgcagctgat taagtcacag aaatttctga 1200

 ataagttggt gatcttggtg gaaacggaga aggagaagat cctgcggaag 1250

 gaatatgttt ttgctgactc caaaaagaga gaaggcttct gccagctcct 1300

 gcagcagatg aagaacaagc actcagagca gccggagccc gacatgatca 1350

 ccatcttcat cggcacctgg aacatgggta acgccccccc tcccaagaag 1400

 atcacgtcct ggtttctctc caaggggcag ggaaagacgc gggacgactc 1450

 tgcggactac atcccccatg acatttacgt gatcggcacc caagaggacc 1500

 ccctgagtga gaaggagtgg ctggagatcc tcaaacactc cctgcaagaa 1550

 atcaccagtg tgacttttaa aacagtcgcc atccacacgc tctggaacat 1600

 ccgcatcgtg gtgctggcca agcctgagca cgagaaccgg atcagccaca 1650

 tctgtactga caacgtgaag acaggcattg caaacacact ggggaacaag 1700

 ggagccgtgg gggtgtcgtt catgttcaat ggaacctcct tagggttcgt 1750

 caacagccac ttgacttcag gaagtgaaaa gaaactcagg cgaaaccaaa 1800

 actatatgaa cattctccgg ttcctggccc tgggcgacaa gaagctgagt 1850

 ccctttaaca tcactcaccg cttcacgcac ctcttctggt ttggggatct 1900

 taactaccgt gtggatctgc ctacctggga ggcagaaacc atcatccaga 1950

 aaatcaagca gcagcagtac gcagacctcc tgtcccacga ccagctgctc 2000

 acagagagga gggagcagaa ggtcttccta cacttcgagg aggaagaaat 2050

 cacgtttgcc ccaacctacc gttttgagag actgactcgg gacaaatacg 2100

 cctacaccaa gcagaaagcg acagggatga agtacaactt gccttcctgg 2150

 tgtgaccgag tcctctggaa gtcttatccc ctggtgcacg tggtgtgtca 2200

 gtcttatggc agtaccagcg acatcatgac gagtgaccac agccctgtct 2250

 ttgccacatt tgaggcagga gtcacttccc agtttgtctc caagaacggt 2300

 cccgggactg ttgacagcca aggacagatt gagtttctca ggtgctatgc 2350

 cacattgaag accaagtccc agaccaaatt ctacctggag ttccactcga 2400

 gctgcttgga gagttttgtc aagagtcagg aaggagaaaa tgaagaagga 2450

 agtgaggggg agctggtggt gaagtttggt gagactcttc caaagctgaa 2500

 gcccattatc tctgaccctg agtacctgct agaccagcac atcctcatca 2550

 gcatcaagtc ctctgacagc gacgaatcct atggcgaggg ctgcattgcc 2600

 cttcggttag aggccacaga aacgcagctg cccatctaca cgcctctcac 2650

 ccaccatggg gagttgacag gccacttcca gggggagatc aagctgcaga 2700

 cctctcaggg caagacgagg gagaagctct atgactttgt gaagacggag 2750

 cgtgatgaat ccagtgggcc aaagaccctg aagagcctca ccagccacga 2800

 ccccatgaag cagtgggaag tcactagcag ggcccctccg tgcagtggct 2850

 ccagcatcac tgaaatcatc aaccccaact acatgggagt ggggcccttt 2900

 gggccaccaa tgcccctgca cgtgaagcag accttgtccc ctgaccagca 2950

 gcccacagcc tggagctacg accagccgcc caaggactcc ccgctggggc 3000

 cctgcagggg agaaagtcct ccgacacctc ccggccagcc gcccatatca 3050

 cccaagaagt ttttaccctc aacagcaaac cggggtctcc ctcccaggac 3100

 acaggagtca aggcccagtg acctggggaa gaacgcaggg gacacgctgc 3150

 ctcaggagga cctgccgctg acgaagcccg agatgtttga gaaccccctg 3200

 tatgggtccc tgagttcctt ccctaagcct gctcccagga aggaccagga 3250

 atcccccaaa atgccgcgga aggaaccccc gccctgcccg gaacccggca 3300

 tcttgtcgcc cagcatcgtg ctcaccaaag cccaggaggc tgatcgcggc 3350

 gaggggcccg gcaagcaggt gcccgcgccc cggctgcgct ccttcacgtg 3400

 ctcatcctct gccgagggca gggcggccgg cggggacaag agccaaggga 3450

 agcccaagac cccggtcagc tcccaggccc cggtgccggc caagaggccc 3500

 atcaagcctt ccagatcgga aatcaaccag cagaccccgc ccaccccgac 3550

 gccgcggccg ccgctgccag tcaagagccc ggcggtgctg cacctccagc 3600

 actccaaggg ccgcgactac cgcgacaaca ccgagctccc gtatcacggc 3650

 aagcaccggc cggaggaggg gccaccaggg cctctaggca ggactgccat 3700

 gcagtgaagc cctcagtgag ctgccactga gtcgggagcc cagaggaacg 3750

 gcgtgaagcc actggaccct ctcccgggac ctcctgctgg ctcctcctgc 3800

 ccagcttcct atgcaaggct ttgtgttttc aggaaagggc ctagcttctg 3850

 tgtggcccac agagttcact gcctgtgaga cttagcacca agtgctgagg 3900

 ctggaagaaa aacgcacacc agacgggcaa caaacagtct gggtccccag 3950

 ctcgctcttg gtacttggga ccccagtgcc ttgttgaggg cgccattctg 4000

 aagaaaggaa ctgcagcgcc gatttgaggg tggagatata gataataata 4050

 atattaataa taataatggc cacatggatc gaacactcat ggtgtgccaa 4100

 gtgctgtgct aagtgcttta cgaacattcg tcatatcagg atgacctcga 4150

 gagctgaggc tctagcacct aaaaccacgt gcccaaaccc accagtttaa 4200

 aacggtgtgt gttcggaggg gtgaaagcat taagaagccc agtgccctcc 4250

 tggagtgaga caagggctcg gccttaagga gctgaagagt ctgggtagct 4300

 tgtttagggt acaagaagcc tgttctgtcc agcttcagtg acacaagctg 4350

 ctttagctaa agtcccgcgg gttccggcat ggctaggctg agagcaggga 4400

 tctacctggc ttctcagttc tttggttgga aggagcagga aatcagctcc 4450

 tattctccag tggagagatc tggcctcagc ttgggctaga gatgccaagg 4500

 cctgtgccag gttccctgtg ccctcctcga ggtgggcagc catcaccagc 4550

 cacagttaag ccaagccccc caacatgtat tccatcgtgc tggtagaaga 4600

 gtctttgctg ttgctcccga aagccgtgct ctccagcctg gctgccaggg 4650

 agggtgggcc tcttggttcc aggctcttga aatagtgcag ccttttcttc 4700

 ctatctctgt ggctttcagc tctgcttcct tggttattag gagaatagat 4750

 gggtgatgtc tttccttatg ttgctttttc aacatagcag aattaatgta 4800

 gggagctaaa tccagtggtg tgtgtgaatg cagaagggaa tgcaccccac 4850

 attcccatga tggaagtctg cgtaaccaat aaattgtgcc tttctcactc 4900

 aaaacc 4906

<210> 858
<211> 1188
<212> PRT
<213> Homo sapien

<400> 858
 Met Val Pro Cys Trp Asn His Gly Asn Ile Thr Arg Ser Lys Ala
   1               5                  10                  15

 Glu Glu Leu Leu Ser Arg Thr Gly Lys Asp Gly Ser Phe Leu Val
                  20                  25                  30

 Arg Ala Ser Glu Ser Ile Ser Arg Ala Tyr Ala Leu Cys Val Leu
                  35                  40                  45

 Tyr Arg Asn Cys Val Tyr Thr Tyr Arg Ile Leu Pro Asn Glu Asp
                  50                  55                  60

 Asp Lys Phe Thr Val Gln Ala Ser Glu Gly Val Ser Met Arg Phe
                  65                  70                  75

 Phe Thr Lys Leu Asp Gln Leu Ile Glu Phe Tyr Lys Lys Glu Asn
                  80                  85                  90

 Met Gly Leu Val Thr His Leu Gln Tyr Pro Val Pro Leu Glu Glu
                  95                 100                 105

 Glu Asp Thr Gly Asp Asp Pro Glu Glu Asp Thr Glu Ser Val Val
                 110                 115                 120

 Ser Pro Pro Glu Leu Pro Pro Arg Asn Ile Pro Leu Thr Ala Ser
                 125                 130                 135

 Ser Cys Glu Ala Lys Glu Val Pro Phe Ser Asn Glu Asn Pro Arg
                 140                 145                 150

 Ala Thr Glu Thr Ser Arg Pro Ser Leu Ser Glu Thr Leu Phe Gln
                 155                 160                 165

 Arg Leu Gln Ser Met Asp Thr Ser Gly Leu Pro Glu Glu His Leu
                 170                 175                 180

 Lys Ala Ile Gln Asp Tyr Leu Ser Thr Gln Leu Ala Gln Asp Ser
                 185                 190                 195

 Glu Phe Val Lys Thr Gly Ser Ser Ser Leu Pro His Leu Lys Lys
                 200                 205                 210

 Leu Thr Thr Leu Leu Cys Lys Glu Leu Tyr Gly Glu Val Ile Arg
                 215                 220                 225

 Thr Leu Pro Ser Leu Glu Ser Leu Gln Arg Leu Phe Asp Gln Gln
                 230                 235                 240

 Leu Ser Pro Gly Leu Arg Pro Arg Pro Gln Val Pro Gly Glu Ala
                 245                 250                 255

 Asn Pro Ile Asn Met Val Ser Lys Leu Ser Gln Leu Thr Ser Leu
                 260                 265                 270

 Leu Ser Ser Ile Glu Asp Lys Val Lys Ala Leu Leu His Glu Gly
                 275                 280                 285

 Pro Glu Ser Pro His Arg Pro Ser Leu Ile Pro Pro Val Thr Phe
                 290                 295                 300

 Glu Val Lys Ala Glu Ser Leu Gly Ile Pro Gln Lys Met Gln Leu
                 305                 310                 315

 Lys Val Asp Val Glu Ser Gly Lys Leu Ile Ile Lys Lys Ser Lys
                 320                 325                 330

 Asp Gly Ser Glu Asp Lys Phe Tyr Ser His Lys Lys Ile Leu Gln
                 335                 340                 345

 Leu Ile Lys Ser Gln Lys Phe Leu Asn Lys Leu Val Ile Leu Val
                 350                 355                 360

 Glu Thr Glu Lys Glu Lys Ile Leu Arg Lys Glu Tyr Val Phe Ala
                 365                 370                 375

 Asp Ser Lys Lys Arg Glu Gly Phe Cys Gln Leu Leu Gln Gln Met
                 380                 385                 390

 Lys Asn Lys His Ser Glu Gln Pro Glu Pro Asp Met Ile Thr Ile
                 395                 400                 405

 Phe Ile Gly Thr Trp Asn Met Gly Asn Ala Pro Pro Pro Lys Lys
                 410                 415                 420

 Ile Thr Ser Trp Phe Leu Ser Lys Gly Gln Gly Lys Thr Arg Asp
                 425                 430                 435

 Asp Ser Ala Asp Tyr Ile Pro His Asp Ile Tyr Val Ile Gly Thr
                 440                 445                 450

 Gln Glu Asp Pro Leu Ser Glu Lys Glu Trp Leu Glu Ile Leu Lys
                 455                 460                 465

 His Ser Leu Gln Glu Ile Thr Ser Val Thr Phe Lys Thr Val Ala
                 470                 475                 480

 Ile His Thr Leu Trp Asn Ile Arg Ile Val Val Leu Ala Lys Pro
                 485                 490                 495

 Glu His Glu Asn Arg Ile Ser His Ile Cys Thr Asp Asn Val Lys
                 500                 505                 510

 Thr Gly Ile Ala Asn Thr Leu Gly Asn Lys Gly Ala Val Gly Val
                 515                 520                 525

 Ser Phe Met Phe Asn Gly Thr Ser Leu Gly Phe Val Asn Ser His
                 530                 535                 540

 Leu Thr Ser Gly Ser Glu Lys Lys Leu Arg Arg Asn Gln Asn Tyr
                 545                 550                 555

 Met Asn Ile Leu Arg Phe Leu Ala Leu Gly Asp Lys Lys Leu Ser
                 560                 565                 570

 Pro Phe Asn Ile Thr His Arg Phe Thr His Leu Phe Trp Phe Gly
                 575                 580                 585

 Asp Leu Asn Tyr Arg Val Asp Leu Pro Thr Trp Glu Ala Glu Thr
                 590                 595                 600

 Ile Ile Gln Lys Ile Lys Gln Gln Gln Tyr Ala Asp Leu Leu Ser
                 605                 610                 615

 His Asp Gln Leu Leu Thr Glu Arg Arg Glu Gln Lys Val Phe Leu
                 620                 625                 630

 His Phe Glu Glu Glu Glu Ile Thr Phe Ala Pro Thr Tyr Arg Phe
                 635                 640                 645

 Glu Arg Leu Thr Arg Asp Lys Tyr Ala Tyr Thr Lys Gln Lys Ala
                 650                 655                 660

 Thr Gly Met Lys Tyr Asn Leu Pro Ser Trp Cys Asp Arg Val Leu
                 665                 670                 675

 Trp Lys Ser Tyr Pro Leu Val His Val Val Cys Gln Ser Tyr Gly
                 680                 685                 690

 Ser Thr Ser Asp Ile Met Thr Ser Asp His Ser Pro Val Phe Ala
                 695                 700                 705

 Thr Phe Glu Ala Gly Val Thr Ser Gln Phe Val Ser Lys Asn Gly
                 710                 715                 720

 Pro Gly Thr Val Asp Ser Gln Gly Gln Ile Glu Phe Leu Arg Cys
                 725                 730                 735

 Tyr Ala Thr Leu Lys Thr Lys Ser Gln Thr Lys Phe Tyr Leu Glu
                 740                 745                 750

 Phe His Ser Ser Cys Leu Glu Ser Phe Val Lys Ser Gln Glu Gly
                 755                 760                 765

 Glu Asn Glu Glu Gly Ser Glu Gly Glu Leu Val Val Lys Phe Gly
                 770                 775                 780

 Glu Thr Leu Pro Lys Leu Lys Pro Ile Ile Ser Asp Pro Glu Tyr
                 785                 790                 795

 Leu Leu Asp Gln His Ile Leu Ile Ser Ile Lys Ser Ser Asp Ser
                 800                 805                 810

 Asp Glu Ser Tyr Gly Glu Gly Cys Ile Ala Leu Arg Leu Glu Ala
                 815                 820                 825

 Thr Glu Thr Gln Leu Pro Ile Tyr Thr Pro Leu Thr His His Gly
                 830                 835                 840

 Glu Leu Thr Gly His Phe Gln Gly Glu Ile Lys Leu Gln Thr Ser
                 845                 850                 855

 Gln Gly Lys Thr Arg Glu Lys Leu Tyr Asp Phe Val Lys Thr Glu
                 860                 865                 870

 Arg Asp Glu Ser Ser Gly Pro Lys Thr Leu Lys Ser Leu Thr Ser
                 875                 880                 885

 His Asp Pro Met Lys Gln Trp Glu Val Thr Ser Arg Ala Pro Pro
                 890                 895                 900

 Cys Ser Gly Ser Ser Ile Thr Glu Ile Ile Asn Pro Asn Tyr Met
                 905                 910                 915

 Gly Val Gly Pro Phe Gly Pro Pro Met Pro Leu His Val Lys Gln
                 920                 925                 930

 Thr Leu Ser Pro Asp Gln Gln Pro Thr Ala Trp Ser Tyr Asp Gln
                 935                 940                 945

 Pro Pro Lys Asp Ser Pro Leu Gly Pro Cys Arg Gly Glu Ser Pro
                 950                 955                 960

 Pro Thr Pro Pro Gly Gln Pro Pro Ile Ser Pro Lys Lys Phe Leu
                 965                 970                 975

 Pro Ser Thr Ala Asn Arg Gly Leu Pro Pro Arg Thr Gln Glu Ser
                 980                 985                 990

 Arg Pro Ser Asp Leu Gly Lys Asn Ala Gly Asp Thr Leu Pro Gln
                 995                1000                1005

 Glu Asp Leu Pro Leu Thr Lys Pro Glu Met Phe Glu Asn Pro Leu
                1010                1015                1020

 Tyr Gly Ser Leu Ser Ser Phe Pro Lys Pro Ala Pro Arg Lys Asp
                1025                1030                1035

 Gln Glu Ser Pro Lys Met Pro Arg Lys Glu Pro Pro Pro Cys Pro
                1040                1045                1050

 Glu Pro Gly Ile Leu Ser Pro Ser Ile Val Leu Thr Lys Ala Gln
                1055                1060                1065

 Glu Ala Asp Arg Gly Glu Gly Pro Gly Lys Gln Val Pro Ala Pro
                1070                1075                1080

 Arg Leu Arg Ser Phe Thr Cys Ser Ser Ser Ala Glu Gly Arg Ala
                1085                1090                1095

 Ala Gly Gly Asp Lys Ser Gln Gly Lys Pro Lys Thr Pro Val Ser
                1100                1105                1110

 Ser Gln Ala Pro Val Pro Ala Lys Arg Pro Ile Lys Pro Ser Arg
                1115                1120                1125

 Ser Glu Ile Asn Gln Gln Thr Pro Pro Thr Pro Thr Pro Arg Pro
                1130                1135                1140

 Pro Leu Pro Val Lys Ser Pro Ala Val Leu His Leu Gln His Ser
                1145                1150                1155

 Lys Gly Arg Asp Tyr Arg Asp Asn Thr Glu Leu Pro Tyr His Gly
                1160                1165                1170

 Lys His Arg Pro Glu Glu Gly Pro Pro Gly Pro Leu Gly Arg Thr
                1175                1180                1185

 Ala Met Gln


<210> 859
<211> 4906
<212> DNA
<213> Homo sapien

<400> 859
 gttgctgtcg ccgttgctgt cggccgaggc caccaagagg caacgggcgg 50

 caggttgcag tggaggggcc tccgctcccc tcggtggtgt gtgggtcctg 100

 ggggtgcctg ccggcccagc cgaggaggcc cacgcccacc atggtcccct 150

 gctggaacca tggcaacatc acccgctcca aggcggagga gctgctttcc 200

 aggacaggca aggacgggag cttcctcgtg cgtgccagcg agtccatctc 250

 ccgggcatac gcgctctgcg tgctgtatcg gaattgcgtt tacacttaca 300

 gaattctgcc caatgaagat gataaattca ctgttcaggc atccgaaggc 350

 gtctccatga ggttcttcac caagctggac cagctcatcg agttttacaa 400

 gaaggaaaac atggggctgg tgacccatct gcaataccct gtgccgctgg 450

 aggaagagga cacaggcgac gaccctgagg aggacacaga aagtgtcgtg 500

 tctccacccg agctgccccc aagaaacatc ccgctgactg ccagctcctg 550

 tgaggccaag gaggttcctt tttcaaacga gaatccccga gcgaccgaga 600

 ccagccggcc gagcctctcc gagacattgt tccagcgact gcaaagcatg 650

 gacaccagtg ggcttccaga agagcatctt aaggccatcc aagattattt 700

 aagcactcag ctcgcccagg actctgaatt tgtgaagaca gggtccagca 750

 gtcttcctca cctgaagaaa ctgaccacac tgctctgcaa ggagctctat 800

 ggagaagtca tccggaccct cccatccctg gagtctctgc agaggttatt 850

 tgaccagcag ctctccccgg gcctccgtcc acgtcctcag gttcctggtg 900

 aggccaatcc catcaacatg gtgtccaagc tcagccaact gacaagcctg 950

 ttgtcgtcca ttgaagacaa ggtcaaggcc ttgctgcacg agggtcctga 1000

 gtctccgcac cggccctccc ttatccctcc agtcaccttt gaggtgaagg 1050

 cagagtctct ggggattcct cagaaaatgc agctcaaagt cgacgttgag 1100

 tctgggaaac tgatcattaa gaagtccaag gatggttctg aggacaagtt 1150

 ctacagccac aagaaaatcc tgcagctgat taagtcacag aaatttctga 1200

 ataagttggt gatcttggtg gaaacggaga aggagaagat cctgcggaag 1250

 gaatatgttt ttgctgactc caaaaagaga gaaggcttct gccagctcct 1300

 gcagcagatg aagaacaagc actcagagca gccggagccc gacatgatca 1350

 ccatcttcat cggcacctgg aacatgggta acgccccccc tcccaagaag 1400

 atcacgtcct ggtttctctc caaggggcag ggaaagacgc gggacgactc 1450

 tgcggactac atcccccatg acatttacgt gatcggcacc caagaggacc 1500

 ccctgagtga gaaggagtgg ctggagatcc tcaaacactc cctgcaagaa 1550

 atcaccagtg tgacttttaa aacagtcgcc atccacacgc tctggaacat 1600

 ccgcatcgtg gtgctggcca agcctgagca cgagaaccgg atcagccaca 1650

 tctgtactga caacgtgaag acaggcattg caaacacact ggggaacaag 1700

 ggagccgtgg gggtgtcgtt catgttcaat ggaacctcct tagggttcgt 1750

 caacagccac ttgacttcag gaagtgaaaa gaaactcagg cgaaaccaaa 1800

 actatatgaa cattctccgg ttcctggccc tgggcgacaa gaagctgagt 1850

 ccctttaaca tcactcaccg cttcacgcac ctcttctggt ttggggatct 1900

 taactaccgt gtggatctgc ctacctggga ggcagaaacc atcatccaga 1950

 aaatcaagca gcagcagtac gcagacctcc tgtcccacga ccagctgctc 2000

 acagagagga gggagcagaa ggtcttccta cacttcgagg aggaagaaat 2050

 cacgtttgcc ccaacctacc gttttgagag actgactcgg gacaaatacg 2100

 cctacaccaa gcagaaagcg acagggatga agtacaactt gccttcctgg 2150

 tgtgaccgag tcctctggaa gtcttatccc ctggtgcacg tggtgtgtca 2200

 gtcttatggc agtaccagcg acatcatgac gagtgaccac agccctgtct 2250

 ttgccacatt tgaggcagga gtcacttccc agtttgtctc caagaacggt 2300

 cccgggactg ttgacagcca aggacagatt gagtttctca ggtgctatgc 2350

 cacattgaag accaagtccc agaccaaatt ctacctggag ttccactcga 2400

 gctgcttgga gagttttgtc aagagtcagg aaggagaaaa tgaagaagga 2450

 agtgaggggg agctggtggt gaagtttggt gagactcttc caaagctgaa 2500

 gcccattatc tctgaccctg agtacctgct agaccagcac atcctcatca 2550

 gcatcaagtc ctctgacagc gacgaatcct atggcgaggg ctgcattgcc 2600

 cttcggttag aggccacaga aacgcagctg cccatctaca cgcctctcac 2650

 ccaccatggg gagttgacag gccacttcca gggggagatc aagctgcaga 2700

 cctctcaggg caagacgagg gagaagctct atgactttgt gaagacggag 2750

 cgtgatgaat ccagtgggcc aaagaccctg aagagcctca ccagccacga 2800

 ccccatgaag cagtgggaag tcactagcag ggcccctccg tgcagtggct 2850

 ccagcatcac tgaaatcatc aaccccaact acatgggagt ggggcccttt 2900

 gggccaccaa tgcccctgca cgtgaagcag accttgtccc ctgaccagca 2950

 gcccacagcc tggagctacg accagccgcc caaggactcc ccgctggggc 3000

 cctgcagggg agaaagtcct ccgacacctc ccggccagcc gcccatatca 3050

 cccaagaagt ttttaccctc aacagcaaac cggggtctcc ctcccaggac 3100

 acaggagtca aggcccagtg acctggggaa gaacgcaggg gacacgctgc 3150

 ctcaggagga cctgccgctg acgaagcccg agatgtttga gaaccccctg 3200

 tatgggtccc tgagttcctt ccctaagcct gctcccagga aggaccagga 3250

 atcccccaaa atgccgcgga aggaaccccc gccctgcccg gaacccggca 3300

 tcttgtcgcc cagcatcgtg ctcaccaaag cccaggaggc tgatcgcggc 3350

 gaggggcccg gcaagcaggt gcccgcgccc cggctgcgct ccttcacgtg 3400

 ctcatcctct gccgagggca gggcggccgg cggggacaag agccaaggga 3450

 agcccaagac cccggtcagc tcccaggccc cggtgccggc caagaggccc 3500

 atcaagcctt ccagatcgga aatcaaccag cagaccccgc ccaccccgac 3550

 gccgcggccg ccgctgccag tcaagagccc ggcggtgctg cacctccagc 3600

 actccaaggg ccgcgactac cgcgacaaca ccgagctccc gtatcacggc 3650

 aagcaccggc cggaggaggg gccaccaggg cctctaggca ggactgccat 3700

 gcagtgaagc cctcagtgag ctgccactga gtcgggagcc cagaggaacg 3750

 gcgtgaagcc actggaccct ctcccgggac ctcctgctgg ctcctcctgc 3800

 ccagcttcct atgcaaggct ttgtgttttc aggaaagggc ctagcttctg 3850

 tgtggcccac agagttcact gcctgtgaga cttagcacca agtgctgagg 3900

 ctggaagaaa aacgcacacc agacgggcaa caaacagtct gggtccccag 3950

 ctcgctcttg gtacttggga ccccagtgcc ttgttgaggg cgccattctg 4000

 aagaaaggaa ctgcagcgcc gatttgaggg tggagatata gataataata 4050

 atattaataa taataatggc cacatggatc gaacactcat ggtgtgccaa 4100

 gtgctgtgct aagtgcttta cgaacattcg tcatatcagg atgacctcga 4150

 gagctgaggc tctagcacct aaaaccacgt gcccaaaccc accagtttaa 4200

 aacggtgtgt gttcggaggg gtgaaagcat taagaagccc agtgccctcc 4250

 tggagtgaga caagggctcg gccttaagga gctgaagagt ctgggtagct 4300

 tgtttagggt acaagaagcc tgttctgtcc agcttcagtg acacaagctg 4350

 ctttagctaa agtcccgcgg gttccggcat ggctaggctg agagcaggga 4400

 tctacctggc ttctcagttc tttggttgga aggagcagga aatcagctcc 4450

 tattctccag tggagagatc tggcctcagc ttgggctaga gatgccaagg 4500

 cctgtgccag gttccctgtg ccctcctcga ggtgggcagc catcaccagc 4550

 cacagttaag ccaagccccc caacatgtat tccatcgtgc tggtagaaga 4600

 gtctttgctg ttgctcccga aagccgtgct ctccagcctg gctgccaggg 4650

 agggtgggcc tcttggttcc aggctcttga aatagtgcag ccttttcttc 4700

 ctatctctgt ggctttcagc tctgcttcct tggttattag gagaatagat 4750

 gggtgatgtc tttccttatg ttgctttttc aacatagcag aattaatgta 4800

 gggagctaaa tccagtggtg tgtgtgaatg cagaagggaa tgcaccccac 4850

 attcccatga tggaagtctg cgtaaccaat aaattgtgcc tttctcactc 4900

 aaaacc 4906

<210> 860
<211> 1188
<212> PRT
<213> Homo sapien

<400> 860
 Met Val Pro Cys Trp Asn His Gly Asn Ile Thr Arg Ser Lys Ala
   1               5                  10                  15

 Glu Glu Leu Leu Ser Arg Thr Gly Lys Asp Gly Ser Phe Leu Val
                  20                  25                  30

 Arg Ala Ser Glu Ser Ile Ser Arg Ala Tyr Ala Leu Cys Val Leu
                  35                  40                  45

 Tyr Arg Asn Cys Val Tyr Thr Tyr Arg Ile Leu Pro Asn Glu Asp
                  50                  55                  60

 Asp Lys Phe Thr Val Gln Ala Ser Glu Gly Val Ser Met Arg Phe
                  65                  70                  75

 Phe Thr Lys Leu Asp Gln Leu Ile Glu Phe Tyr Lys Lys Glu Asn
                  80                  85                  90

 Met Gly Leu Val Thr His Leu Gln Tyr Pro Val Pro Leu Glu Glu
                  95                 100                 105

 Glu Asp Thr Gly Asp Asp Pro Glu Glu Asp Thr Glu Ser Val Val
                 110                 115                 120

 Ser Pro Pro Glu Leu Pro Pro Arg Asn Ile Pro Leu Thr Ala Ser
                 125                 130                 135

 Ser Cys Glu Ala Lys Glu Val Pro Phe Ser Asn Glu Asn Pro Arg
                 140                 145                 150

 Ala Thr Glu Thr Ser Arg Pro Ser Leu Ser Glu Thr Leu Phe Gln
                 155                 160                 165

 Arg Leu Gln Ser Met Asp Thr Ser Gly Leu Pro Glu Glu His Leu
                 170                 175                 180

 Lys Ala Ile Gln Asp Tyr Leu Ser Thr Gln Leu Ala Gln Asp Ser
                 185                 190                 195

 Glu Phe Val Lys Thr Gly Ser Ser Ser Leu Pro His Leu Lys Lys
                 200                 205                 210

 Leu Thr Thr Leu Leu Cys Lys Glu Leu Tyr Gly Glu Val Ile Arg
                 215                 220                 225

 Thr Leu Pro Ser Leu Glu Ser Leu Gln Arg Leu Phe Asp Gln Gln
                 230                 235                 240

 Leu Ser Pro Gly Leu Arg Pro Arg Pro Gln Val Pro Gly Glu Ala
                 245                 250                 255

 Asn Pro Ile Asn Met Val Ser Lys Leu Ser Gln Leu Thr Ser Leu
                 260                 265                 270

 Leu Ser Ser Ile Glu Asp Lys Val Lys Ala Leu Leu His Glu Gly
                 275                 280                 285

 Pro Glu Ser Pro His Arg Pro Ser Leu Ile Pro Pro Val Thr Phe
                 290                 295                 300

 Glu Val Lys Ala Glu Ser Leu Gly Ile Pro Gln Lys Met Gln Leu
                 305                 310                 315

 Lys Val Asp Val Glu Ser Gly Lys Leu Ile Ile Lys Lys Ser Lys
                 320                 325                 330

 Asp Gly Ser Glu Asp Lys Phe Tyr Ser His Lys Lys Ile Leu Gln
                 335                 340                 345

 Leu Ile Lys Ser Gln Lys Phe Leu Asn Lys Leu Val Ile Leu Val
                 350                 355                 360

 Glu Thr Glu Lys Glu Lys Ile Leu Arg Lys Glu Tyr Val Phe Ala
                 365                 370                 375

 Asp Ser Lys Lys Arg Glu Gly Phe Cys Gln Leu Leu Gln Gln Met
                 380                 385                 390

 Lys Asn Lys His Ser Glu Gln Pro Glu Pro Asp Met Ile Thr Ile
                 395                 400                 405

 Phe Ile Gly Thr Trp Asn Met Gly Asn Ala Pro Pro Pro Lys Lys
                 410                 415                 420

 Ile Thr Ser Trp Phe Leu Ser Lys Gly Gln Gly Lys Thr Arg Asp
                 425                 430                 435

 Asp Ser Ala Asp Tyr Ile Pro His Asp Ile Tyr Val Ile Gly Thr
                 440                 445                 450

 Gln Glu Asp Pro Leu Ser Glu Lys Glu Trp Leu Glu Ile Leu Lys
                 455                 460                 465

 His Ser Leu Gln Glu Ile Thr Ser Val Thr Phe Lys Thr Val Ala
                 470                 475                 480

 Ile His Thr Leu Trp Asn Ile Arg Ile Val Val Leu Ala Lys Pro
                 485                 490                 495

 Glu His Glu Asn Arg Ile Ser His Ile Cys Thr Asp Asn Val Lys
                 500                 505                 510

 Thr Gly Ile Ala Asn Thr Leu Gly Asn Lys Gly Ala Val Gly Val
                 515                 520                 525

 Ser Phe Met Phe Asn Gly Thr Ser Leu Gly Phe Val Asn Ser His
                 530                 535                 540

 Leu Thr Ser Gly Ser Glu Lys Lys Leu Arg Arg Asn Gln Asn Tyr
                 545                 550                 555

 Met Asn Ile Leu Arg Phe Leu Ala Leu Gly Asp Lys Lys Leu Ser
                 560                 565                 570

 Pro Phe Asn Ile Thr His Arg Phe Thr His Leu Phe Trp Phe Gly
                 575                 580                 585

 Asp Leu Asn Tyr Arg Val Asp Leu Pro Thr Trp Glu Ala Glu Thr
                 590                 595                 600

 Ile Ile Gln Lys Ile Lys Gln Gln Gln Tyr Ala Asp Leu Leu Ser
                 605                 610                 615

 His Asp Gln Leu Leu Thr Glu Arg Arg Glu Gln Lys Val Phe Leu
                 620                 625                 630

 His Phe Glu Glu Glu Glu Ile Thr Phe Ala Pro Thr Tyr Arg Phe
                 635                 640                 645

 Glu Arg Leu Thr Arg Asp Lys Tyr Ala Tyr Thr Lys Gln Lys Ala
                 650                 655                 660

 Thr Gly Met Lys Tyr Asn Leu Pro Ser Trp Cys Asp Arg Val Leu
                 665                 670                 675

 Trp Lys Ser Tyr Pro Leu Val His Val Val Cys Gln Ser Tyr Gly
                 680                 685                 690

 Ser Thr Ser Asp Ile Met Thr Ser Asp His Ser Pro Val Phe Ala
                 695                 700                 705

 Thr Phe Glu Ala Gly Val Thr Ser Gln Phe Val Ser Lys Asn Gly
                 710                 715                 720

 Pro Gly Thr Val Asp Ser Gln Gly Gln Ile Glu Phe Leu Arg Cys
                 725                 730                 735

 Tyr Ala Thr Leu Lys Thr Lys Ser Gln Thr Lys Phe Tyr Leu Glu
                 740                 745                 750

 Phe His Ser Ser Cys Leu Glu Ser Phe Val Lys Ser Gln Glu Gly
                 755                 760                 765

 Glu Asn Glu Glu Gly Ser Glu Gly Glu Leu Val Val Lys Phe Gly
                 770                 775                 780

 Glu Thr Leu Pro Lys Leu Lys Pro Ile Ile Ser Asp Pro Glu Tyr
                 785                 790                 795

 Leu Leu Asp Gln His Ile Leu Ile Ser Ile Lys Ser Ser Asp Ser
                 800                 805                 810

 Asp Glu Ser Tyr Gly Glu Gly Cys Ile Ala Leu Arg Leu Glu Ala
                 815                 820                 825

 Thr Glu Thr Gln Leu Pro Ile Tyr Thr Pro Leu Thr His His Gly
                 830                 835                 840

 Glu Leu Thr Gly His Phe Gln Gly Glu Ile Lys Leu Gln Thr Ser
                 845                 850                 855

 Gln Gly Lys Thr Arg Glu Lys Leu Tyr Asp Phe Val Lys Thr Glu
                 860                 865                 870

 Arg Asp Glu Ser Ser Gly Pro Lys Thr Leu Lys Ser Leu Thr Ser
                 875                 880                 885

 His Asp Pro Met Lys Gln Trp Glu Val Thr Ser Arg Ala Pro Pro
                 890                 895                 900

 Cys Ser Gly Ser Ser Ile Thr Glu Ile Ile Asn Pro Asn Tyr Met
                 905                 910                 915

 Gly Val Gly Pro Phe Gly Pro Pro Met Pro Leu His Val Lys Gln
                 920                 925                 930

 Thr Leu Ser Pro Asp Gln Gln Pro Thr Ala Trp Ser Tyr Asp Gln
                 935                 940                 945

 Pro Pro Lys Asp Ser Pro Leu Gly Pro Cys Arg Gly Glu Ser Pro
                 950                 955                 960

 Pro Thr Pro Pro Gly Gln Pro Pro Ile Ser Pro Lys Lys Phe Leu
                 965                 970                 975

 Pro Ser Thr Ala Asn Arg Gly Leu Pro Pro Arg Thr Gln Glu Ser
                 980                 985                 990

 Arg Pro Ser Asp Leu Gly Lys Asn Ala Gly Asp Thr Leu Pro Gln
                 995                1000                1005

 Glu Asp Leu Pro Leu Thr Lys Pro Glu Met Phe Glu Asn Pro Leu
                1010                1015                1020

 Tyr Gly Ser Leu Ser Ser Phe Pro Lys Pro Ala Pro Arg Lys Asp
                1025                1030                1035

 Gln Glu Ser Pro Lys Met Pro Arg Lys Glu Pro Pro Pro Cys Pro
                1040                1045                1050

 Glu Pro Gly Ile Leu Ser Pro Ser Ile Val Leu Thr Lys Ala Gln
                1055                1060                1065

 Glu Ala Asp Arg Gly Glu Gly Pro Gly Lys Gln Val Pro Ala Pro
                1070                1075                1080

 Arg Leu Arg Ser Phe Thr Cys Ser Ser Ser Ala Glu Gly Arg Ala
                1085                1090                1095

 Ala Gly Gly Asp Lys Ser Gln Gly Lys Pro Lys Thr Pro Val Ser
                1100                1105                1110

 Ser Gln Ala Pro Val Pro Ala Lys Arg Pro Ile Lys Pro Ser Arg
                1115                1120                1125

 Ser Glu Ile Asn Gln Gln Thr Pro Pro Thr Pro Thr Pro Arg Pro
                1130                1135                1140

 Pro Leu Pro Val Lys Ser Pro Ala Val Leu His Leu Gln His Ser
                1145                1150                1155

 Lys Gly Arg Asp Tyr Arg Asp Asn Thr Glu Leu Pro Tyr His Gly
                1160                1165                1170

 Lys His Arg Pro Glu Glu Gly Pro Pro Gly Pro Leu Gly Arg Thr
                1175                1180                1185

 Ala Met Gln


<210> 861
<211> 2997
<212> DNA
<213> Homo sapien

<400> 861
 caagaggtgc agagcaagcg catgcgtcgt gacggcccgg cttaggcgac 50

 tctgggcggg tctgggccgc tccagtgttt tggggcacag aagctgtggg 100

 aggagctgga ggcttcaccg tggtaaccac agcgccgctg ctgccccgcc 150

 ttgcaggcct caggactgtc atcgcctctg ggtgtgaggg tactttggcc 200

 accgtccccg gaaataaccg cgcctgcctc tcaagatacc ccatcctctc 250

 cacgccgctg ccgctgccgc catgcaaggg gaggacgcca gatacctcaa 300

 aaggaaagtt aaaggaggga atatagatgt acatccatca gaaaaagcac 350

 tcattgttca ctatgaagtg gaagctacca ttcttggaga aatgggggac 400

 cccatgttgg gagaacgaaa agaatgtcaa aaaatcattc gacttaagag 450

 tctcaatgcc aacacagata taacttccct ggcaaggaag gtggttgaag 500

 aatgtaaact cattcatcct tcaaaactaa atgaggtaga acagctgttg 550

 tactatctac agaaccgccg tgattcattg tcaggaaaag agaaaaaaga 600

 aaaatcaagc aagcctaaag atccacctcc ttttgaagga atggagattg 650

 atgaagttgc taacattaat gacatggatg aatatattga gttattatat 700

 gaagatattc ctgacaaagt tcggggttct gctttgatcc tgcagcttgc 750

 tcgaaatcct gataacttgg aagaactact attgaatgaa actgcccttg 800

 gtgcattagc aagggtcctg agagaagact ggaagcaaag tgtcgagtta 850

 gctacaaaca taatttacat ctttttttgt ttctccagct tttctcaatt 900

 tcatggactt attactcact ataaaattgg agctctgtgt atgaatatta 950

 ttgatcatga gttaaaaaga catgagcttt ggcaagaaga actctcaaag 1000

 aagaagaaag ctgttgatga agaccctgaa aaccaaacct tgagaaagga 1050

 ttatgaaaaa acctttaaaa agtaccaggg gcttgtggta aaacaggaac 1100

 agctattacg agttgctctt tatttgcttc tgaatcttgc tgaggatact 1150

 cgtaccgaac tgaaaatgag gaacaagaac atagttcaca tgttggtgaa 1200

 agcccttgat cgggacaatt ttgagctgct aattttagtt gtgtcattct 1250

 tgaagaaact cagcattttt atggagaata aaaatgatat ggtggaaatg 1300

 gatattgttg aaaaactggt gaaaatgata ccttgtgagc atgaagacct 1350

 gctgaatatc accctccgac ttttactaaa cctatccttt gacacaggac 1400

 tgaggaataa gatggtacaa gttggactgc ttcccaagct cactgcactc 1450

 ctaggcaatg acaactacaa acaaatagca atgtgtgttc tttaccacat 1500

 aagcatggat gaccgcttta aatcaatgtt tgcatacact gactgtatac 1550

 cacagttaat gaagatgctg tttgaatgtt cagatgaacg aattgacttg 1600

 gaactcattt ctttctgcat taatcttgct gctaacaaaa gaaatgtaca 1650

 gcttatctgt gaaggaaatg ggctgaagat gctcatgaag agggctctga 1700

 agtttaagga tccattgctg atgaaaatga ttagaaacat ttctcagcat 1750

 gatggaccaa ctaaaaatct gtttattgat tatgttgggg accttgcagc 1800

 ccagatctct aatgatgaag aagaggagtt tgtgattgaa tgtttgggaa 1850

 ctcttgcaaa cttgaccatt ccagacttag actgggaatt ggttcttaaa 1900

 gaatataagt tggttccata cctcaaggat aaactaaaac caggtgctgc 1950

 agaagatgat cttgttttag aagtggttat aatgattgga actgtatcca 2000

 tggatgactc ttgtgctgca ttgctagcca aatctggcat aatccctgca 2050

 ctcattgaat tgctaaatgc tcaacaagaa gatgatgaat ttgtgtgtca 2100

 gataatttat gtcttctacc agatggtttt ccaccaagcc acaagagacg 2150

 tcataatcaa ggaaacacag gctccagcat atctcataga cctaatgcat 2200

 gataagaata atgaaatccg aaaggtctgt gataatacat tagatattat 2250

 agcggaatat gatgaagaat gggctaagaa aattcagagt gaaaagtttc 2300

 gctggcataa ctctcagtgg ctggagatgg tagagagtcg tcagatggat 2350

 gagagtgagc agtacttgta tggtgatgat cgaattgagc catacattca 2400

 tgaaggagat attctcgaaa gacctgacct tttctacaac tcagatggat 2450

 taattgcctc tgaaggagcc ataagtcccg atttcttcaa tgattaccac 2500

 cttcaaaatg gagatgttgt tgggcagcat tcatttcctg gcagccttgg 2550

 aatggatggc tttggccaac cagttggcat tcttggacgc cctgccacag 2600

 catatggatt ccgccctgat gaaccttact actatggcta tggatcttga 2650

 taaagtatct gtttccatgt gtaatctcag cttagaagaa atctgtgtgg 2700

 gttgggttaa ttttggatct ttgcctaata atgcatgttg atgttattgt 2750

 gggtctgtgt ttgtttttat ttttatatgt tgttagctgc agattaaccc 2800

 cagcccctct gtcttctgtt aagtacagtt gatactgaca ttgttcactc 2850

 atcaaaccac atcttgatgc taagtaacat ttcccatgag cctcaaaact 2900

 gaatgctgaa aagctactag actggaaaac aaacactgca ttatgtatgt 2950

 taagtgacta atttaatttc aattaaaaag cgtaaagtga aaatgaa 2997

<210> 862
<211> 792
<212> PRT
<213> Homo sapien

<400> 862
 Met Gln Gly Glu Asp Ala Arg Tyr Leu Lys Arg Lys Val Lys Gly
   1               5                  10                  15

 Gly Asn Ile Asp Val His Pro Ser Glu Lys Ala Leu Ile Val His
                  20                  25                  30

 Tyr Glu Val Glu Ala Thr Ile Leu Gly Glu Met Gly Asp Pro Met
                  35                  40                  45

 Leu Gly Glu Arg Lys Glu Cys Gln Lys Ile Ile Arg Leu Lys Ser
                  50                  55                  60

 Leu Asn Ala Asn Thr Asp Ile Thr Ser Leu Ala Arg Lys Val Val
                  65                  70                  75

 Glu Glu Cys Lys Leu Ile His Pro Ser Lys Leu Asn Glu Val Glu
                  80                  85                  90

 Gln Leu Leu Tyr Tyr Leu Gln Asn Arg Arg Asp Ser Leu Ser Gly
                  95                 100                 105

 Lys Glu Lys Lys Glu Lys Ser Ser Lys Pro Lys Asp Pro Pro Pro
                 110                 115                 120

 Phe Glu Gly Met Glu Ile Asp Glu Val Ala Asn Ile Asn Asp Met
                 125                 130                 135

 Asp Glu Tyr Ile Glu Leu Leu Tyr Glu Asp Ile Pro Asp Lys Val
                 140                 145                 150

 Arg Gly Ser Ala Leu Ile Leu Gln Leu Ala Arg Asn Pro Asp Asn
                 155                 160                 165

 Leu Glu Glu Leu Leu Leu Asn Glu Thr Ala Leu Gly Ala Leu Ala
                 170                 175                 180

 Arg Val Leu Arg Glu Asp Trp Lys Gln Ser Val Glu Leu Ala Thr
                 185                 190                 195

 Asn Ile Ile Tyr Ile Phe Phe Cys Phe Ser Ser Phe Ser Gln Phe
                 200                 205                 210

 His Gly Leu Ile Thr His Tyr Lys Ile Gly Ala Leu Cys Met Asn
                 215                 220                 225

 Ile Ile Asp His Glu Leu Lys Arg His Glu Leu Trp Gln Glu Glu
                 230                 235                 240

 Leu Ser Lys Lys Lys Lys Ala Val Asp Glu Asp Pro Glu Asn Gln
                 245                 250                 255

 Thr Leu Arg Lys Asp Tyr Glu Lys Thr Phe Lys Lys Tyr Gln Gly
                 260                 265                 270

 Leu Val Val Lys Gln Glu Gln Leu Leu Arg Val Ala Leu Tyr Leu
                 275                 280                 285

 Leu Leu Asn Leu Ala Glu Asp Thr Arg Thr Glu Leu Lys Met Arg
                 290                 295                 300

 Asn Lys Asn Ile Val His Met Leu Val Lys Ala Leu Asp Arg Asp
                 305                 310                 315

 Asn Phe Glu Leu Leu Ile Leu Val Val Ser Phe Leu Lys Lys Leu
                 320                 325                 330

 Ser Ile Phe Met Glu Asn Lys Asn Asp Met Val Glu Met Asp Ile
                 335                 340                 345

 Val Glu Lys Leu Val Lys Met Ile Pro Cys Glu His Glu Asp Leu
                 350                 355                 360

 Leu Asn Ile Thr Leu Arg Leu Leu Leu Asn Leu Ser Phe Asp Thr
                 365                 370                 375

 Gly Leu Arg Asn Lys Met Val Gln Val Gly Leu Leu Pro Lys Leu
                 380                 385                 390

 Thr Ala Leu Leu Gly Asn Asp Asn Tyr Lys Gln Ile Ala Met Cys
                 395                 400                 405

 Val Leu Tyr His Ile Ser Met Asp Asp Arg Phe Lys Ser Met Phe
                 410                 415                 420

 Ala Tyr Thr Asp Cys Ile Pro Gln Leu Met Lys Met Leu Phe Glu
                 425                 430                 435

 Cys Ser Asp Glu Arg Ile Asp Leu Glu Leu Ile Ser Phe Cys Ile
                 440                 445                 450

 Asn Leu Ala Ala Asn Lys Arg Asn Val Gln Leu Ile Cys Glu Gly
                 455                 460                 465

 Asn Gly Leu Lys Met Leu Met Lys Arg Ala Leu Lys Phe Lys Asp
                 470                 475                 480

 Pro Leu Leu Met Lys Met Ile Arg Asn Ile Ser Gln His Asp Gly
                 485                 490                 495

 Pro Thr Lys Asn Leu Phe Ile Asp Tyr Val Gly Asp Leu Ala Ala
                 500                 505                 510

 Gln Ile Ser Asn Asp Glu Glu Glu Glu Phe Val Ile Glu Cys Leu
                 515                 520                 525

 Gly Thr Leu Ala Asn Leu Thr Ile Pro Asp Leu Asp Trp Glu Leu
                 530                 535                 540

 Val Leu Lys Glu Tyr Lys Leu Val Pro Tyr Leu Lys Asp Lys Leu
                 545                 550                 555

 Lys Pro Gly Ala Ala Glu Asp Asp Leu Val Leu Glu Val Val Ile
                 560                 565                 570

 Met Ile Gly Thr Val Ser Met Asp Asp Ser Cys Ala Ala Leu Leu
                 575                 580                 585

 Ala Lys Ser Gly Ile Ile Pro Ala Leu Ile Glu Leu Leu Asn Ala
                 590                 595                 600

 Gln Gln Glu Asp Asp Glu Phe Val Cys Gln Ile Ile Tyr Val Phe
                 605                 610                 615

 Tyr Gln Met Val Phe His Gln Ala Thr Arg Asp Val Ile Ile Lys
                 620                 625                 630

 Glu Thr Gln Ala Pro Ala Tyr Leu Ile Asp Leu Met His Asp Lys
                 635                 640                 645

 Asn Asn Glu Ile Arg Lys Val Cys Asp Asn Thr Leu Asp Ile Ile
                 650                 655                 660

 Ala Glu Tyr Asp Glu Glu Trp Ala Lys Lys Ile Gln Ser Glu Lys
                 665                 670                 675

 Phe Arg Trp His Asn Ser Gln Trp Leu Glu Met Val Glu Ser Arg
                 680                 685                 690

 Gln Met Asp Glu Ser Glu Gln Tyr Leu Tyr Gly Asp Asp Arg Ile
                 695                 700                 705

 Glu Pro Tyr Ile His Glu Gly Asp Ile Leu Glu Arg Pro Asp Leu
                 710                 715                 720

 Phe Tyr Asn Ser Asp Gly Leu Ile Ala Ser Glu Gly Ala Ile Ser
                 725                 730                 735

 Pro Asp Phe Phe Asn Asp Tyr His Leu Gln Asn Gly Asp Val Val
                 740                 745                 750

 Gly Gln His Ser Phe Pro Gly Ser Leu Gly Met Asp Gly Phe Gly
                 755                 760                 765

 Gln Pro Val Gly Ile Leu Gly Arg Pro Ala Thr Ala Tyr Gly Phe
                 770                 775                 780

 Arg Pro Asp Glu Pro Tyr Tyr Tyr Gly Tyr Gly Ser
                 785                 790

<210> 863
<211> 1390
<212> DNA
<213> Homo sapien

<400> 863
 gggaagtgct gttggagccg ctgtggttgc tgtccgcgga gtggaagcgc 50

 gtgcttttgt ttgtgtccct ggccatggcg ctgcagctct cccgggagca 100

 gggaatcacc ctgcgcggga gcgccgaaat cgtggccgag ttcttctcat 150

 tcggcatcaa cagcatttta tatcagcgtg gcatatatcc atctgaaacc 200

 tttactcgag tgcagaaata cggactcacc ttgcttgtaa ctactgatct 250

 tgagctcata aaatacctaa ataatgtggt ggaacaactg aaagattggt 300

 tatacaagtg ttcagttcag aaactggttg tagttatctc aaatattgaa 350

 agtggtgagg tcctggaaag atggcagttt gatattgagt gtgacaagac 400

 tgcaaaagat gacagtgcac ccagagaaaa gtctcagaaa gctatccagg 450

 atgaaatccg ttcagtgatc agacagatca cagctacggt gacatttctg 500

 ccactgttgg aagtttcttg ttcatttgat ctgctgattt atacagacaa 550

 agatttggtt gtacctgaaa aatgggaaga gtcgggacca cagtttatta 600

 ccaattctga ggaagtccgc cttcgttcat ttactactac aatccacaaa 650

 gtaaatagca tggtggccta caaaattcct gtcaatgact gaggatgaca 700

 tgaggaaaat aatgtaattg taattttgaa atgtggtttt cctgaaatca 750

 ggtcatctat agttgatatg ttttatttca ttggttaatt tttacatgga 800

 gaaaaccaaa atgatactta ctgaactgtg tgtaattgtt cctttatttt 850

 tttggtacct atttgactta ccatggagtt aacatcatga atttattgca 900

 cattgttcaa aaggaaccag gaggtttttt tgtcaacatt gtgatgtata 950

 ttcctttgaa gatagtaact gtagatggaa aaacttgtgc tataaagcta 1000

 gatgctttcc taaatcagat gttttggtca agtagtttga ctcagtatag 1050

 gtagggagat atttaagtat aaaatacaac aaaggaagtc taaatattca 1100

 gaatctttgt taaggtcctg aaagtaactc ataatctata aacaatgaaa 1150

 tattgctgta tagctccttt tgaccttcat ttcatgtata gttttcccta 1200

 ttgaatcagt ttccaattat ttgactttaa tttatgtaac ttgaacctat 1250

 gaagcaatgg atatttgtac tgtttaatgt tctgtgatac agaactctta 1300

 aaaatgtttt ttcatgtgtt ttataaaatc aagttttaag tgaaagtgag 1350

 gaaataaagt taagtttgtt ttaaaaaaaa aaaaaaaaaa 1390

<210> 864
<211> 205
<212> PRT
<213> Homo sapien

<400> 864
 Met Ala Leu Gln Leu Ser Arg Glu Gln Gly Ile Thr Leu Arg Gly
   1               5                  10                  15

 Ser Ala Glu Ile Val Ala Glu Phe Phe Ser Phe Gly Ile Asn Ser
                  20                  25                  30

 Ile Leu Tyr Gln Arg Gly Ile Tyr Pro Ser Glu Thr Phe Thr Arg
                  35                  40                  45

 Val Gln Lys Tyr Gly Leu Thr Leu Leu Val Thr Thr Asp Leu Glu
                  50                  55                  60

 Leu Ile Lys Tyr Leu Asn Asn Val Val Glu Gln Leu Lys Asp Trp
                  65                  70                  75

 Leu Tyr Lys Cys Ser Val Gln Lys Leu Val Val Val Ile Ser Asn
                  80                  85                  90

 Ile Glu Ser Gly Glu Val Leu Glu Arg Trp Gln Phe Asp Ile Glu
                  95                 100                 105

 Cys Asp Lys Thr Ala Lys Asp Asp Ser Ala Pro Arg Glu Lys Ser
                 110                 115                 120

 Gln Lys Ala Ile Gln Asp Glu Ile Arg Ser Val Ile Arg Gln Ile
                 125                 130                 135

 Thr Ala Thr Val Thr Phe Leu Pro Leu Leu Glu Val Ser Cys Ser
                 140                 145                 150

 Phe Asp Leu Leu Ile Tyr Thr Asp Lys Asp Leu Val Val Pro Glu
                 155                 160                 165

 Lys Trp Glu Glu Ser Gly Pro Gln Phe Ile Thr Asn Ser Glu Glu
                 170                 175                 180

 Val Arg Leu Arg Ser Phe Thr Thr Thr Ile His Lys Val Asn Ser
                 185                 190                 195

 Met Val Ala Tyr Lys Ile Pro Val Asn Asp
                 200                 205

<210> 865
<211> 1471
<212> DNA
<213> Homo sapien

<400> 865
 gtggccgcgc aggaggacgg agccctaacc gcaacccgcg ccgcgccgcg 50

 ccgatttgat ttgtatccac tgtcaccagc actgctcact taggactttc 100

 tggatccaga cccaggcagc gcacactgga ctcttgagga agaaggagac 150

 tctaattttg gattccttgg tggaggaaaa taaaacactc tggtcttgcc 200

 gccaacgatg caagtgtgac tgctggcgtc ttcatgagct ccagaggtca 250

 cagcacgcta ccaaggactc tcatggcccc tcggatgatt tccgagggag 300

 acataggagg cattgctcaa atcacctcct ctctattcct gggcagaggc 350

 agtgtggcct ccaatcggca cctcctccag gctcgtggca tcacctgcat 400

 tgttaatgct accattgaga tccctaattt caactggccc caatttgagt 450

 atgttaaagt gcctctggct gacatgccgc atgcccccat tggactgtac 500

 tttgacaccg tggctgacaa gatccacagt gtgagcagga agcacggggc 550

 caccttggtg cactgtgctg caggggtgag ccgctcagcc acgctgtgta 600

 tcgcgtacct gatgaaattc cacaacgtgt gcctgctgga ggcatacaac 650

 tgggtgaaag cccggcgacc tgtcatcagg cccaacgtag gcttctggag 700

 gcaactgata gactacgagc gccagctctt tgggaagtcg acagttaaaa 750

 tggtacagac accttatggc atagttcccg acgtctatga gaaggagtcc 800

 cgacacctga tgccttactg ggggatttag tgccactgaa gcctgcgtca 850

 gcagcccgag cggggccggc atctgctccc cgccgtctgc tccctctcca 900

 ctctcttctc aaatggctga cttctggttc tccctcaagt gttttttaca 950

 ctgggtgttc aaatttattt taagagatag ggagggaggg gacataaagg 1000

 gaatgcatac attgctagtc acatttttaa aattaacatt ttggaatagt 1050

 gtttatggaa atctttagct tttaatcatt tttaccaatt tgaacagttt 1100

 aataaactgg ttctgctctc ttctgaatct catgcctttg gcaccttggt 1150

 aggtgcagga ggagctcagt gcaaaaatca ctttggggcc tcattaaccc 1200

 tttagagaca agctttgccc caggctgcgg accagacaga tgcttaggga 1250

 aggttgatac cagcttcagt ctctactgga ttagccctac tctttccttt 1300

 cccctccatt atttagtgac tctgtaagta agttaaatac acccttatta 1350

 tttagctgtt aagtaactat aatgaaatct gctgcaaaat ctctcttgga 1400

 atccatgtgc ccaggattat attagcatta tttttaataa atctatatgc 1450

 ttaaaaaaaa aaaaaaaaaa a 1471

<210> 866
<211> 198
<212> PRT
<213> Homo sapien

<400> 866
 Met Ser Ser Arg Gly His Ser Thr Leu Pro Arg Thr Leu Met Ala
   1               5                  10                  15

 Pro Arg Met Ile Ser Glu Gly Asp Ile Gly Gly Ile Ala Gln Ile
                  20                  25                  30

 Thr Ser Ser Leu Phe Leu Gly Arg Gly Ser Val Ala Ser Asn Arg
                  35                  40                  45

 His Leu Leu Gln Ala Arg Gly Ile Thr Cys Ile Val Asn Ala Thr
                  50                  55                  60

 Ile Glu Ile Pro Asn Phe Asn Trp Pro Gln Phe Glu Tyr Val Lys
                  65                  70                  75

 Val Pro Leu Ala Asp Met Pro His Ala Pro Ile Gly Leu Tyr Phe
                  80                  85                  90

 Asp Thr Val Ala Asp Lys Ile His Ser Val Ser Arg Lys His Gly
                  95                 100                 105

 Ala Thr Leu Val His Cys Ala Ala Gly Val Ser Arg Ser Ala Thr
                 110                 115                 120

 Leu Cys Ile Ala Tyr Leu Met Lys Phe His Asn Val Cys Leu Leu
                 125                 130                 135

 Glu Ala Tyr Asn Trp Val Lys Ala Arg Arg Pro Val Ile Arg Pro
                 140                 145                 150

 Asn Val Gly Phe Trp Arg Gln Leu Ile Asp Tyr Glu Arg Gln Leu
                 155                 160                 165

 Phe Gly Lys Ser Thr Val Lys Met Val Gln Thr Pro Tyr Gly Ile
                 170                 175                 180

 Val Pro Asp Val Tyr Glu Lys Glu Ser Arg His Leu Met Pro Tyr
                 185                 190                 195

 Trp Gly Ile


<210> 867
<211> 2564
<212> DNA
<213> Homo sapien

<400> 867
 ggggcggtcg cagctgaagc aggcctaccc tctgaagagg tccaagcaac 50

 ggaagtacta ctacgaagct gcctttctgg ccatccttga gaaaaataga 100

 cagatggcca aggagagggg cctaataagc cccagtgatt ttgcccagct 150

 gcaaaaatac atggaatact ccaccaaaaa ggtcagtgat gtcctaaagc 200

 tcttcgagga tggcgagatg gctaaatatg tccaaggaga tgccattggg 250

 tacgagggat tccagcaatt cctgaaaatc tatctcgaag tggataatgt 300

 tcccagacac ctaagcctgg cactgtttca atcctttgag actggtcact 350

 gcttaaatga gacaaatgtg acaaaagatg tggtgtgtct caatgatgtt 400

 tcctgctact tttcccttct ggagggtggt cggccagaag acaagttaga 450

 attcaccttc aagctgtacg acacggacag aaatgggatc ctggacagct 500

 cagaagtgga caaaattatc ctacagatga tgcgagtggc tgaatacctg 550

 gattgggatg tgtctgagct gaggccgatt cttcaggaga tgatgaaaga 600

 gattgactat gatggcagtg gctctgtctc tcaagctgag tgggtccggg 650

 ctggggccac caccgtgcca ctgctagtgc tgctgggtct ggagatgact 700

 ctgaaggacg acggacagca catgtggagg cccaagaggt tccccagacc 750

 agtctactgc aatctgtgcg agtcaagcat tggtcttggc aaacagggac 800

 tgagctgtaa cctctgtaag tacactgttc acgaccagtg tgccatgaaa 850

 gccctgcctt gtgaagtcag cacctatgcc aagtctcgga aggacattgg 900

 tgtccaatca catgtgtggg tgcgaggagg ctgtgagtcc gggcgctgcg 950

 accgctgtca gaaaaagatc cggatctacc acagtctgac cgggctgcat 1000

 tgtgtatggt gccacctaga gatccacgat gactgcctgc aagcggtggg 1050

 ccatgagtgt gactgtgggc tgctccggga tcacatcctg cctccatctt 1100

 ccatctatcc cagtgtcctg gcctctggac cggatcgtaa aaatagcaaa 1150

 acaagccaga agaccatgga tgatttaaat ttgagcacct ctgaggctct 1200

 gcggattgac cctgttccta acacccaccc acttctcgtc tttgtcaatc 1250

 ctaagagtgg cgggaagcag gggcagaggg tgctctggaa gttccagtat 1300

 atattaaacc ctcgacaggt gttcaacctc ctaaaggatg gtcctgagat 1350

 agggctccga ttattcaagg atgttcctga tagccggatt ttggtgtgtg 1400

 gtggagacgg cacagtaggc tggattctag agaccattga caaagctaac 1450

 ttgccagttt tgcctcctgt tgctgtgttg cccctgggta ctggaaatga 1500

 tctggctcga tgcctaagat ggggaggagg ttatgaagga cagaatctgg 1550

 caaagatcct caaggattta gagatgagta aagtggtaca tatggatcga 1600

 tggtctgtgg aggtgatacc tcaacaaact gaagaaaaaa gtgacccagt 1650

 cccctttcaa atcatcaata actacttctc tattggcgtg gatgcctcta 1700

 ttgctcatcg attccacatc atgcgagaga aatatccgga gaagttcaac 1750

 agcagaatga agaacaagct atggtacttc gaatttgcca catctgaatc 1800

 catcttctca acatgcaaaa agctggagga gtctttgaca gttgagatct 1850

 gtgggaaacc gctggatctg agcaacctgt ccctagaagg catcgcagtg 1900

 ctaaacatcc ctagcatgca tggtggctcc aacctctggg gtgataccag 1950

 gagaccccat ggggatatct atgggatcaa ccaggcctta ggtgctacag 2000

 ctaaagtcat caccgaccct gatatcctga aaacctgtgt accagaccta 2050

 agtgacaaga gactggaagt ggttgggctg gagggtgcaa ttgagatggg 2100

 ccaaatctat accaagctca agaatgctgg acgtcggctg gccaagtgct 2150

 ctgagatcac cttccacacc acaaaaaccc ttcccatgca aattgacgta 2200

 gaaccctgga tgcagacgcc ctgtacaatc aagatcaccc acaagaacca 2250

 gatgcccatg ctcatgggcc cacccccccg ctccaccaat ttctttggct 2300

 tcttgagcta agggggacac ccttggcctc caagccagcc ttgaacccac 2350

 ctccctgtcc ctggactcta ctcccgaggc tctgtacatt gctgccacat 2400

 actcctgcca gcttggggga gtgttccttc accctcacag tatttattat 2450

 cctgcaccac ctcactgttc cccatgcgca cacacataca cacaccccaa 2500

 aacacataca ttgaaagtgc ctcatctgaa taaaatgact tgtgtttccc 2550

 tttgggatct gctg 2564

<210> 868
<211> 735
<212> PRT
<213> Homo sapien

<400> 868
 Met Ala Lys Glu Arg Gly Leu Ile Ser Pro Ser Asp Phe Ala Gln
   1               5                  10                  15

 Leu Gln Lys Tyr Met Glu Tyr Ser Thr Lys Lys Val Ser Asp Val
                  20                  25                  30

 Leu Lys Leu Phe Glu Asp Gly Glu Met Ala Lys Tyr Val Gln Gly
                  35                  40                  45

 Asp Ala Ile Gly Tyr Glu Gly Phe Gln Gln Phe Leu Lys Ile Tyr
                  50                  55                  60

 Leu Glu Val Asp Asn Val Pro Arg His Leu Ser Leu Ala Leu Phe
                  65                  70                  75

 Gln Ser Phe Glu Thr Gly His Cys Leu Asn Glu Thr Asn Val Thr
                  80                  85                  90

 Lys Asp Val Val Cys Leu Asn Asp Val Ser Cys Tyr Phe Ser Leu
                  95                 100                 105

 Leu Glu Gly Gly Arg Pro Glu Asp Lys Leu Glu Phe Thr Phe Lys
                 110                 115                 120

 Leu Tyr Asp Thr Asp Arg Asn Gly Ile Leu Asp Ser Ser Glu Val
                 125                 130                 135

 Asp Lys Ile Ile Leu Gln Met Met Arg Val Ala Glu Tyr Leu Asp
                 140                 145                 150

 Trp Asp Val Ser Glu Leu Arg Pro Ile Leu Gln Glu Met Met Lys
                 155                 160                 165

 Glu Ile Asp Tyr Asp Gly Ser Gly Ser Val Ser Gln Ala Glu Trp
                 170                 175                 180

 Val Arg Ala Gly Ala Thr Thr Val Pro Leu Leu Val Leu Leu Gly
                 185                 190                 195

 Leu Glu Met Thr Leu Lys Asp Asp Gly Gln His Met Trp Arg Pro
                 200                 205                 210

 Lys Arg Phe Pro Arg Pro Val Tyr Cys Asn Leu Cys Glu Ser Ser
                 215                 220                 225

 Ile Gly Leu Gly Lys Gln Gly Leu Ser Cys Asn Leu Cys Lys Tyr
                 230                 235                 240

 Thr Val His Asp Gln Cys Ala Met Lys Ala Leu Pro Cys Glu Val
                 245                 250                 255

 Ser Thr Tyr Ala Lys Ser Arg Lys Asp Ile Gly Val Gln Ser His
                 260                 265                 270

 Val Trp Val Arg Gly Gly Cys Glu Ser Gly Arg Cys Asp Arg Cys
                 275                 280                 285

 Gln Lys Lys Ile Arg Ile Tyr His Ser Leu Thr Gly Leu His Cys
                 290                 295                 300

 Val Trp Cys His Leu Glu Ile His Asp Asp Cys Leu Gln Ala Val
                 305                 310                 315

 Gly His Glu Cys Asp Cys Gly Leu Leu Arg Asp His Ile Leu Pro
                 320                 325                 330

 Pro Ser Ser Ile Tyr Pro Ser Val Leu Ala Ser Gly Pro Asp Arg
                 335                 340                 345

 Lys Asn Ser Lys Thr Ser Gln Lys Thr Met Asp Asp Leu Asn Leu
                 350                 355                 360

 Ser Thr Ser Glu Ala Leu Arg Ile Asp Pro Val Pro Asn Thr His
                 365                 370                 375

 Pro Leu Leu Val Phe Val Asn Pro Lys Ser Gly Gly Lys Gln Gly
                 380                 385                 390

 Gln Arg Val Leu Trp Lys Phe Gln Tyr Ile Leu Asn Pro Arg Gln
                 395                 400                 405

 Val Phe Asn Leu Leu Lys Asp Gly Pro Glu Ile Gly Leu Arg Leu
                 410                 415                 420

 Phe Lys Asp Val Pro Asp Ser Arg Ile Leu Val Cys Gly Gly Asp
                 425                 430                 435

 Gly Thr Val Gly Trp Ile Leu Glu Thr Ile Asp Lys Ala Asn Leu
                 440                 445                 450

 Pro Val Leu Pro Pro Val Ala Val Leu Pro Leu Gly Thr Gly Asn
                 455                 460                 465

 Asp Leu Ala Arg Cys Leu Arg Trp Gly Gly Gly Tyr Glu Gly Gln
                 470                 475                 480

 Asn Leu Ala Lys Ile Leu Lys Asp Leu Glu Met Ser Lys Val Val
                 485                 490                 495

 His Met Asp Arg Trp Ser Val Glu Val Ile Pro Gln Gln Thr Glu
                 500                 505                 510

 Glu Lys Ser Asp Pro Val Pro Phe Gln Ile Ile Asn Asn Tyr Phe
                 515                 520                 525

 Ser Ile Gly Val Asp Ala Ser Ile Ala His Arg Phe His Ile Met
                 530                 535                 540

 Arg Glu Lys Tyr Pro Glu Lys Phe Asn Ser Arg Met Lys Asn Lys
                 545                 550                 555

 Leu Trp Tyr Phe Glu Phe Ala Thr Ser Glu Ser Ile Phe Ser Thr
                 560                 565                 570

 Cys Lys Lys Leu Glu Glu Ser Leu Thr Val Glu Ile Cys Gly Lys
                 575                 580                 585

 Pro Leu Asp Leu Ser Asn Leu Ser Leu Glu Gly Ile Ala Val Leu
                 590                 595                 600

 Asn Ile Pro Ser Met His Gly Gly Ser Asn Leu Trp Gly Asp Thr
                 605                 610                 615

 Arg Arg Pro His Gly Asp Ile Tyr Gly Ile Asn Gln Ala Leu Gly
                 620                 625                 630

 Ala Thr Ala Lys Val Ile Thr Asp Pro Asp Ile Leu Lys Thr Cys
                 635                 640                 645

 Val Pro Asp Leu Ser Asp Lys Arg Leu Glu Val Val Gly Leu Glu
                 650                 655                 660

 Gly Ala Ile Glu Met Gly Gln Ile Tyr Thr Lys Leu Lys Asn Ala
                 665                 670                 675

 Gly Arg Arg Leu Ala Lys Cys Ser Glu Ile Thr Phe His Thr Thr
                 680                 685                 690

 Lys Thr Leu Pro Met Gln Ile Asp Val Glu Pro Trp Met Gln Thr
                 695                 700                 705

 Pro Cys Thr Ile Lys Ile Thr His Lys Asn Gln Met Pro Met Leu
                 710                 715                 720

 Met Gly Pro Pro Pro Arg Ser Thr Asn Phe Phe Gly Phe Leu Ser
                 725                 730                 735

<210> 869
<211> 6430
<212> DNA
<213> Homo sapien

<400> 869
 gcggccgcgg ggaccctcgg cgtggtcctc tgaccctgca aacccgcgac 50

 ggaggaaggg gaggtcctgc ccgaggcgcc agcccgagga ggaggatgcc 100

 catttaaccc gccctcgcct gccgggcgct tgcctcggtg cccgccgccg 150

 gagcctccga gccgcgcccg tggaagtgct gcatggggca gggctgctga 200

 agcgcggagt tcggggtcgc gccgctccca ggcaggcgcg ggagcccggt 250

 gcggcagttg gcacagtttc ggcggcgcct tctgcgcggg agtggggggc 300

 gcggtgcgcc cggcacggcc tccgcggtgc cctggtgagg cgagagttat 350

 ggagccgccc agctgcattc aggatgagcc gttcccgcac cccctggagc 400

 ccgagccggg cgtctcagct cagcccggcc cggggaagcc aagcgataag 450

 cggttccggc tgtggtacgt tggggggtcg tgcctggacc acaggaccac 500

 gctgcctatg ctgccctggc tcatggccga gatccgcagg cgcagccaga 550

 agcccgaggc gggcggctgc ggggcgccgg cggcccgaga ggtgatcctg 600

 gtgctcagcg cgcccttcct gcgttgcgtc cccgcgccgg gcgctggggc 650

 ctcggggggc actagtccgt cggccacgca gcccaacccg gcggtattca 700

 tcttcgagca caaggcgcag catatctcgc gcttcatcca caacagccac 750

 gacctcacct actttgccta cctgatcaag gcgcagcccg acgaccccga 800

 gtcgcagatg gcctgccacg ttttccgcgc cacagacccc agccaggttc 850

 ctgatgttat tagcagccat aaggcaatta tctaaagcgg ccatgaaaga 900

 ggatgccaaa cccagcaaag ataatgagga cgccttttac aactctcaga 950

 agttcgaagt cctgtactgt ggaaaggtga ccgtgaccca caagaaggcc 1000

 ccctcaagcc tcatcgatga ctgcatggag aagttcagcc tgcacgaaca 1050

 gcagcgcctg aagatccaag gcgagcagcg cggtccggac ccaggagagg 1100

 acctggctga cttggaggtg gtggtgcccg ggtcccccgg agactgcctg 1150

 ccggaggagg ctgacggcac cgacacccac cttggcttac ctgccggggc 1200

 cagccagcct gccctgacca gctctcgggt ctgcttccct gagcggattt 1250

 tggaagattc tggctttgat gagcagcagg agtttcggtc tcggtgcagc 1300

 agtgtcaccg gcgtgcaacg gagagttcac gagggcagcc agaaatccca 1350

 gccgcgacgg agacacgcga gcgcacccag tcacgtccag ccctcggact 1400

 cggagaagaa caggaccatg ctcttccagg ttgggcgatt tgagattaac 1450

 cttatcagtc cagacactaa atcagttgtg ctagaaaaga attttaaaga 1500

 tatctcctct tgttctcagg gtataaagca tgtggatcac tttggcttta 1550

 tctgccggga gtctccagag cctggactta gccagtatat ttgttatgta 1600

 ttccagtgtg ccagcgaatc tctggttgat gaggtaatgc tgactctgaa 1650

 acaggccttc agtacggcgg ctgccctgca gagtgccaag acgcagatta 1700

 aactgtgtga ggcctgcccg atgcactctt tgcataagct ctgtgaaagg 1750

 attgaaggtc tctacccacc aagagccaag ctggtgatac agaggcatct 1800

 ctcatcactg acagataatg agcaagctga catctttgaa agagttcaga 1850

 aaatgaagcc agtcagtgac caggaagaaa atgaacttgt gattttacac 1900

 ctgaggcagc tgtgtgaagc caagcagaag acacacgtgc acatcgggga 1950

 aggcccttct actatttcaa atagtacaat cccagaaaat gcaacaagca 2000

 gtggaaggtt caaacttgac attctgaaaa ataaagctaa gagatcctta 2050

 actagctccc tggaaaatat cttctcaagg ggagctaaca gaatgagagg 2100

 tcggcttgga agtgtggaca gttttgaacg gtccaacagt cttgcttcag 2150

 agaaggacta ctcaccaggg gattctccac cagggacacc gccagcgtcc 2200

 ccaccgtcct cagcttggca aacgtttccc gaagaggatt ccgactcccc 2250

 gcagtttcga agacgggcac acacgttcag ccacccacct tcaagcacaa 2300

 agagaaagct gaatttgcag gatgggaggg ctcagggtgt gcgttcccct 2350

 ctgctgaggc agagctccag tgaacagtgc agcaatcttt cgtcagttcg 2400

 acgcatgtac aaggagagta attcttcctc cagtcttcca agtcttcaca 2450

 cttccttctc tgccccttcc ttcactgccc cctctttcct gaaaagcttt 2500

 taccagaatt caggtagact gtccccacag tatgaaaatg aaatcagaca 2550

 agacactgct tcagaatcaa gtgatggaga agggagaaaa aggacctcat 2600

 ctacctgcag caatgagtcc ctaagtgtgg gaggaacctc tgtcactcct 2650

 cgccggatct cctggcggca gcgcattttc ctcagggttg cttctcccat 2700

 gaacaaatct ccctcagcaa tgcaacagca agatggattg gacaggaacg 2750

 agctgctgcc actgtccccc ctctctccaa ccatggagga ggaaccgctg 2800

 gttatattcc tgtctgggga ggatgaccca gaaaagattg aagaaagaaa 2850

 gaaatcaaaa gaactgagga gcttgtggag aaaagctata caccaacaaa 2900

 tcttgttact tcgaatggaa aaagaaaacc agaaacttga agcaagcaga 2950

 gatgaactcc agtccagaaa agttaaatta gactatgaag aagttggtgc 3000

 atgtcagaaa gaggtcttaa taacttggga taagaagttg ttaaactgca 3050

 gagctaaaat cagatgtgat atggaagata ttcatactct tcttaaagaa 3100

 ggagttccca aaagtcgacg aggagaaatt tggcagtttc tggctttaca 3150

 gtaccgactc agacacagat tgcctaataa acaacagcct cctgacatat 3200

 cctataagga acttttgaag cagctcactg ctcagcagca tgcgattctc 3250

 gtggatttag gaaggacgtt tcctactcac ccttactttt cagtacagct 3300

 tgggccagga cagctgtcac tgtttaacct cctgaaagcc tattctttgc 3350

 tggacaaaga agtgggatac tgtcagggga tcagctttgt ggctggagtc 3400

 ctgcttctgc acatgagtga agagcaagcc tttgaaatgc tgaaattcct 3450

 catgtatgac ctcggcttcc gcaagcagta cagacctgac atgatgtcgc 3500

 tgcagattca aatgtaccag ctgtccaggc tccttcatga ctatcacaga 3550

 gatctctaca atcaccttga agaaaatgaa atcagcccca gtctttatgc 3600

 tgccccctgg ttcctcacat tgtttgcctc tcagttttca ttaggatttg 3650

 tagccagagt ttttgatatt atttttcttc agggaactga agttatattc 3700

 aaggttgcac tcagcctact gagcagccaa gagacactta taatggaatg 3750

 tgagagcttt gaaaatattg ttgagtttct taaaaacacg ctacctgata 3800

 tgaatacctc tgaaatggaa aaaattatta cccaggtttt tgagatggat 3850

 atttctaagc agttgcatgc ctatgaggtg gaatatcatg tgctacagga 3900

 tgagcttcag gaatcttcat attcctgtga ggatagtgaa actttggaga 3950

 agctggagag ggccaatagc caactgaaaa gacaaaacat ggacctccta 4000

 gaaaaattac aggtagctca tactaaaatc caggccttgg aatcaaacct 4050

 ggaaaatctt ttgacgagag agaccaaaat gaagtcttta atccggaccc 4100

 tggaacaaga aaaaatggct tatcaaaaga cagtggagca actccggaag 4150

 ctgctgcccg cggatgctct agtcaattgt gacctgttgc tgagagacct 4200

 aaactgcaac cctaacaaca aagccaagat aggaaataag ccataattga 4250

 agaggcacgg cctcagcaga aagtgctcct tagaatacta cagagaggaa 4300

 gagcctgcat gtcgctggcc caaggctgga ccctgaagct gatggaacca 4350

 cctaatactg gtgctgagct cctagtcaca gcaggtggac ctcgtgctca 4400

 tcagagcatg ccaatcctaa gccattggac atatgtagac tggtttttgt 4450

 tgttgctatg tacgtataaa tatatatata aaatgaacat agttcatgct 4500

 ttcagataaa atgagtagat gtatatttag attaattttt ttagtcagaa 4550

 cttcatgaaa tccacaccaa aggaaaggta aactgaaatt tcccttggac 4600

 atatgtgaaa tctttttgtc tttatagtga aacaaagcca gagcatcttt 4650

 gtatattgca atatacttga aaaaaatgaa tgtatttttt tctccaaaga 4700

 acagcatgtt tcactcaatg gtgaaaaggt ggaaacattt atgtaacttt 4750

 atgtgtatct gtcttgatat ctactgacat tgtctatatg aggaaaatga 4800

 ttactggtca tgctcctgtg agttttttgg gaaggtaggg tcatttctcc 4850

 ctgcctgctt tgtgccaact agcatgttgc atctacatgc attatgagtc 4900

 tggttaggca ttactttaaa catacataaa gagacagtag gacattgtgg 4950

 ctgagtctac ccagctcaag gtaaaggaga atgttgctaa ttttttagca 5000

 aactagacca gcattattac tcaaactaaa aatatcacac ctgaaaaatt 5050

 taatttagga cctaaaatgt ctagattagc tttctgcttt ttttatttga 5100

 ataactcatt cagttgtgaa tgaattcctc tttatttggt gccacagtca 5150

 ccaaatgaca aggatttgcc actttcccac caaattgtga gtgcttgtaa 5200

 tttaggtctc tctaccttaa attcaatata aggaaacgta attatgattg 5250

 attttttcca aagatgacaa gctgtgttga aatacatttt ttcttttgac 5300

 caattgacag aatctaataa gctttaataa tcttcccctt ttatgtgaaa 5350

 agttttgaga actgtgaaat gtttaggaac aaactgttga aatccattgg 5400

 aagggaaaaa agaaagtggt accagtgtta ccagctcaac taaaacctgc 5450

 aattctgcat ttcaactctt cacttcctca gcctacaaat agctcattag 5500

 atgacattca cgcatgctgg gtataggcaa ggaaagtaat tttcaaagta 5550

 catttgcagt tctctttttc agagatgatt ctatgatagt gcctctgaaa 5600

 gttgatgcag catttttgcc tttccaaaaa gtatttatcc tcactgcttt 5650

 ttgcagtact tgtattttca cagatggatt atctggggta attttcttca 5700

 aagggagttt gttatacaca gtgaaaatgt attatagagt agaatagtaa 5750

 agctctaggg gtttcagaaa gctttgatga acagatgaca aacatctgaa 5800

 accccctccg cactgttacc cagtgtgtat ataatgactt gttatagctc 5850

 agtgtgccct tgaatccata cagtttctta aaagacaata aaatcttatt 5900

 aataaagtta atgtaacttc taagttctag aaaatgctga ttctgtctgc 5950

 cccattcaat tgggggctac taattgattt gttgcttgga tttcctgaga 6000

 atttctctat ttgtaggagg ggttttttct ttttacggtc tgttgatgac 6050

 aattacttta tgggtgtgat gcaccgatgg tagccaagga atctgttggg 6100

 gaagttcgga aagaaacctt ttctttcttt tattcagttt aaagtaaact 6150

 ttatcctgga tgtttagaat caacattaag agttatatta tggtgttcag 6200

 agattaagct gacttggata caatattttc ttttgaaaat gaattttctt 6250

 tttcatttgt gatttttaaa aaatgttgca ccagttatgc ttcatgcatc 6300

 gttacatctt catcaggtta atgtaatgtc tagttccttt gcaataaata 6350

 tattgctgca gcttcaaaaa aatctatgtc gggtgcggag aaagaggtaa 6400

 tgaaatggca ggaattcgat atcagcttat 6430

<210> 870
<211> 1117
<212> PRT
<213> Homo sapien

<400> 870
 Met Lys Glu Asp Ala Lys Pro Ser Lys Asp Asn Glu Asp Ala Phe
   1               5                  10                  15

 Tyr Asn Ser Gln Lys Phe Glu Val Leu Tyr Cys Gly Lys Val Thr
                  20                  25                  30

 Val Thr His Lys Lys Ala Pro Ser Ser Leu Ile Asp Asp Cys Met
                  35                  40                  45

 Glu Lys Phe Ser Leu His Glu Gln Gln Arg Leu Lys Ile Gln Gly
                  50                  55                  60

 Glu Gln Arg Gly Pro Asp Pro Gly Glu Asp Leu Ala Asp Leu Glu
                  65                  70                  75

 Val Val Val Pro Gly Ser Pro Gly Asp Cys Leu Pro Glu Glu Ala
                  80                  85                  90

 Asp Gly Thr Asp Thr His Leu Gly Leu Pro Ala Gly Ala Ser Gln
                  95                 100                 105

 Pro Ala Leu Thr Ser Ser Arg Val Cys Phe Pro Glu Arg Ile Leu
                 110                 115                 120

 Glu Asp Ser Gly Phe Asp Glu Gln Gln Glu Phe Arg Ser Arg Cys
                 125                 130                 135

 Ser Ser Val Thr Gly Val Gln Arg Arg Val His Glu Gly Ser Gln
                 140                 145                 150

 Lys Ser Gln Pro Arg Arg Arg His Ala Ser Ala Pro Ser His Val
                 155                 160                 165

 Gln Pro Ser Asp Ser Glu Lys Asn Arg Thr Met Leu Phe Gln Val
                 170                 175                 180

 Gly Arg Phe Glu Ile Asn Leu Ile Ser Pro Asp Thr Lys Ser Val
                 185                 190                 195

 Val Leu Glu Lys Asn Phe Lys Asp Ile Ser Ser Cys Ser Gln Gly
                 200                 205                 210

 Ile Lys His Val Asp His Phe Gly Phe Ile Cys Arg Glu Ser Pro
                 215                 220                 225

 Glu Pro Gly Leu Ser Gln Tyr Ile Cys Tyr Val Phe Gln Cys Ala
                 230                 235                 240

 Ser Glu Ser Leu Val Asp Glu Val Met Leu Thr Leu Lys Gln Ala
                 245                 250                 255

 Phe Ser Thr Ala Ala Ala Leu Gln Ser Ala Lys Thr Gln Ile Lys
                 260                 265                 270

 Leu Cys Glu Ala Cys Pro Met His Ser Leu His Lys Leu Cys Glu
                 275                 280                 285

 Arg Ile Glu Gly Leu Tyr Pro Pro Arg Ala Lys Leu Val Ile Gln
                 290                 295                 300

 Arg His Leu Ser Ser Leu Thr Asp Asn Glu Gln Ala Asp Ile Phe
                 305                 310                 315

 Glu Arg Val Gln Lys Met Lys Pro Val Ser Asp Gln Glu Glu Asn
                 320                 325                 330

 Glu Leu Val Ile Leu His Leu Arg Gln Leu Cys Glu Ala Lys Gln
                 335                 340                 345

 Lys Thr His Val His Ile Gly Glu Gly Pro Ser Thr Ile Ser Asn
                 350                 355                 360

 Ser Thr Ile Pro Glu Asn Ala Thr Ser Ser Gly Arg Phe Lys Leu
                 365                 370                 375

 Asp Ile Leu Lys Asn Lys Ala Lys Arg Ser Leu Thr Ser Ser Leu
                 380                 385                 390

 Glu Asn Ile Phe Ser Arg Gly Ala Asn Arg Met Arg Gly Arg Leu
                 395                 400                 405

 Gly Ser Val Asp Ser Phe Glu Arg Ser Asn Ser Leu Ala Ser Glu
                 410                 415                 420

 Lys Asp Tyr Ser Pro Gly Asp Ser Pro Pro Gly Thr Pro Pro Ala
                 425                 430                 435

 Ser Pro Pro Ser Ser Ala Trp Gln Thr Phe Pro Glu Glu Asp Ser
                 440                 445                 450

 Asp Ser Pro Gln Phe Arg Arg Arg Ala His Thr Phe Ser His Pro
                 455                 460                 465

 Pro Ser Ser Thr Lys Arg Lys Leu Asn Leu Gln Asp Gly Arg Ala
                 470                 475                 480

 Gln Gly Val Arg Ser Pro Leu Leu Arg Gln Ser Ser Ser Glu Gln
                 485                 490                 495

 Cys Ser Asn Leu Ser Ser Val Arg Arg Met Tyr Lys Glu Ser Asn
                 500                 505                 510

 Ser Ser Ser Ser Leu Pro Ser Leu His Thr Ser Phe Ser Ala Pro
                 515                 520                 525

 Ser Phe Thr Ala Pro Ser Phe Leu Lys Ser Phe Tyr Gln Asn Ser
                 530                 535                 540

 Gly Arg Leu Ser Pro Gln Tyr Glu Asn Glu Ile Arg Gln Asp Thr
                 545                 550                 555

 Ala Ser Glu Ser Ser Asp Gly Glu Gly Arg Lys Arg Thr Ser Ser
                 560                 565                 570

 Thr Cys Ser Asn Glu Ser Leu Ser Val Gly Gly Thr Ser Val Thr
                 575                 580                 585

 Pro Arg Arg Ile Ser Trp Arg Gln Arg Ile Phe Leu Arg Val Ala
                 590                 595                 600

 Ser Pro Met Asn Lys Ser Pro Ser Ala Met Gln Gln Gln Asp Gly
                 605                 610                 615

 Leu Asp Arg Asn Glu Leu Leu Pro Leu Ser Pro Leu Ser Pro Thr
                 620                 625                 630

 Met Glu Glu Glu Pro Leu Val Ile Phe Leu Ser Gly Glu Asp Asp
                 635                 640                 645

 Pro Glu Lys Ile Glu Glu Arg Lys Lys Ser Lys Glu Leu Arg Ser
                 650                 655                 660

 Leu Trp Arg Lys Ala Ile His Gln Gln Ile Leu Leu Leu Arg Met
                 665                 670                 675

 Glu Lys Glu Asn Gln Lys Leu Glu Ala Ser Arg Asp Glu Leu Gln
                 680                 685                 690

 Ser Arg Lys Val Lys Leu Asp Tyr Glu Glu Val Gly Ala Cys Gln
                 695                 700                 705

 Lys Glu Val Leu Ile Thr Trp Asp Lys Lys Leu Leu Asn Cys Arg
                 710                 715                 720

 Ala Lys Ile Arg Cys Asp Met Glu Asp Ile His Thr Leu Leu Lys
                 725                 730                 735

 Glu Gly Val Pro Lys Ser Arg Arg Gly Glu Ile Trp Gln Phe Leu
                 740                 745                 750

 Ala Leu Gln Tyr Arg Leu Arg His Arg Leu Pro Asn Lys Gln Gln
                 755                 760                 765

 Pro Pro Asp Ile Ser Tyr Lys Glu Leu Leu Lys Gln Leu Thr Ala
                 770                 775                 780

 Gln Gln His Ala Ile Leu Val Asp Leu Gly Arg Thr Phe Pro Thr
                 785                 790                 795

 His Pro Tyr Phe Ser Val Gln Leu Gly Pro Gly Gln Leu Ser Leu
                 800                 805                 810

 Phe Asn Leu Leu Lys Ala Tyr Ser Leu Leu Asp Lys Glu Val Gly
                 815                 820                 825

 Tyr Cys Gln Gly Ile Ser Phe Val Ala Gly Val Leu Leu Leu His
                 830                 835                 840

 Met Ser Glu Glu Gln Ala Phe Glu Met Leu Lys Phe Leu Met Tyr
                 845                 850                 855

 Asp Leu Gly Phe Arg Lys Gln Tyr Arg Pro Asp Met Met Ser Leu
                 860                 865                 870

 Gln Ile Gln Met Tyr Gln Leu Ser Arg Leu Leu His Asp Tyr His
                 875                 880                 885

 Arg Asp Leu Tyr Asn His Leu Glu Glu Asn Glu Ile Ser Pro Ser
                 890                 895                 900

 Leu Tyr Ala Ala Pro Trp Phe Leu Thr Leu Phe Ala Ser Gln Phe
                 905                 910                 915

 Ser Leu Gly Phe Val Ala Arg Val Phe Asp Ile Ile Phe Leu Gln
                 920                 925                 930

 Gly Thr Glu Val Ile Phe Lys Val Ala Leu Ser Leu Leu Ser Ser
                 935                 940                 945

 Gln Glu Thr Leu Ile Met Glu Cys Glu Ser Phe Glu Asn Ile Val
                 950                 955                 960

 Glu Phe Leu Lys Asn Thr Leu Pro Asp Met Asn Thr Ser Glu Met
                 965                 970                 975

 Glu Lys Ile Ile Thr Gln Val Phe Glu Met Asp Ile Ser Lys Gln
                 980                 985                 990

 Leu His Ala Tyr Glu Val Glu Tyr His Val Leu Gln Asp Glu Leu
                 995                1000                1005

 Gln Glu Ser Ser Tyr Ser Cys Glu Asp Ser Glu Thr Leu Glu Lys
                1010                1015                1020

 Leu Glu Arg Ala Asn Ser Gln Leu Lys Arg Gln Asn Met Asp Leu
                1025                1030                1035

 Leu Glu Lys Leu Gln Val Ala His Thr Lys Ile Gln Ala Leu Glu
                1040                1045                1050

 Ser Asn Leu Glu Asn Leu Leu Thr Arg Glu Thr Lys Met Lys Ser
                1055                1060                1065

 Leu Ile Arg Thr Leu Glu Gln Glu Lys Met Ala Tyr Gln Lys Thr
                1070                1075                1080

 Val Glu Gln Leu Arg Lys Leu Leu Pro Ala Asp Ala Leu Val Asn
                1085                1090                1095

 Cys Asp Leu Leu Leu Arg Asp Leu Asn Cys Asn Pro Asn Asn Lys
                1100                1105                1110

 Ala Lys Ile Gly Asn Lys Pro
                1115

<210> 871
<211> 5922
<212> DNA
<213> Homo sapien

<400> 871
 gcggccgcgg ggaccctcgg cgtggtcctc tgaccctgca aacccgcgac 50

 ggaggaaggg gaggtcctgc ccgaggcgcc agcccgagga ggaggatgcc 100

 catttaaccc gccctcgcct gccgggcgct tgcctcggtg cccgccgccg 150

 gagcctccga gccgcgcccg tggaagtgct gcatggggca gggctgctga 200

 agcgcggagt tcggggtcgc gccgctccca ggcaggcgcg ggagcccggt 250

 gcggcagttg gcacagtttc ggcggcgcct tctgcgcggg agtggggggc 300

 gcggtgcgcc cggccggcct ccgcggtgcc ctggtgaggc gagagttatg 350

 gagccgccca gctgcattca ggatgagccg ttcccgcacc ccctggagcc 400

 cgagccgggc gtctcagctc agcccggccc cgggaagcca agcgataagc 450

 ggttccggct gtggtacgtt ggggggtcgt gcctggacca caggaccacg 500

 ctgcctatgc tgccctggct catggccgag atccgcaggc gcagccagaa 550

 gcccgaggcg ggcggctgcg gggcgccggc ggcccgagag gtgatcctgg 600

 tgctcagcgc gcccttcctg cgttgcgtcc ccgcgccggg cgctggggcc 650

 tcggggggca ctagtccgtc ggccacgcag cccaacccgg cggtattcat 700

 cttcgagcac aaggcgcagc atatctcgcg cttcatccac aacagccacg 750

 acctcaccta ctttgcctac ctgatcaagg cgcagcccga cgaccccgag 800

 tcgcagatgg cctgccacgt tttccgcgcc acagacccca gccaggttcc 850

 tgatgttatt agcagcataa ggcaattatc taaagcggcc atgaaagagg 900

 atgccaaacc cagcaaagat aatgaggacg ccttttacaa ctctcagaag 950

 ttcgaagtcc tgtactgtgg aaaggtgacc gtgacccaca agaaggcccc 1000

 ctcaagcctc atcgatgact gcatggagaa gttcagcctg cacgaacagc 1050

 agcgcctgaa gatccaaggc gagcagcgcg gtccggaccc aggagaggac 1100

 ctggctgact tggaggtggt ggtgcccggg tcccccggag actgcctgcc 1150

 ggaggaggct gacggcaccg acacccacct tggcttacct gccggggcca 1200

 gccagcctgc cctgaccagc tctcgggtct gcttccctga gcggattttg 1250

 gaagattctg gctttgatga gcagcaggag tttcggtctc ggtgcagcag 1300

 tgtcaccggc gtgcaacgga gagttcacga gggcagccag aaatcccagc 1350

 cgcgacggag acacgcgagc gcacccagtc acgtccagcc ctcggactcg 1400

 gagaagaaca ggaccatgct cttccaggtt gggcgatttg agattaacct 1450

 tatcagtcca gacactaaat cagttgtgct agaaaagaat tttaaagata 1500

 tctcctcttg ttctcagggt ataaagcatg tggatcactt tggctttatc 1550

 tgccgggagt ctccagagcc tggacttagc cagtatattt gttatgtatt 1600

 ccagtgtgcc agcgaatctc tggttgatga ggtaatgctg actctgaaac 1650

 aggccttcag tacggcggct gccctgcaga gtgccaagac gcagattaaa 1700

 ctgtgtgagg cctgcccgat gcactctttg cataagctct gtgaaaggat 1750

 tgaaggtctc tacccaccaa gagccaagct ggtgatacag aggcatctct 1800

 catcactgac agataatgag caagctgaca tctttgaaag agttcagaaa 1850

 atgaagccag tcagtgacca ggaagaaaat gaacttgtga ttttacacct 1900

 gaggcagctg tgtgaagcca agcagaagac acacgtgcac atcggggaag 1950

 gcccttctac tatttcaaat agtacaatcc cagaaaatgc aacaagcagt 2000

 ggaaggttca aacttgacat tctgaaaaat aaagctaaga gatccttaac 2050

 tagctccctg gaaaatatct tctcaagggg agctaacaga atgagaggtc 2100

 ggcttggaag tgtggacagt tttgaacggt ccaacagtct tgcttcagag 2150

 aaggactact caccagggga ttctccacca gggacaccgc cagcgtcccc 2200

 accgtcctca gcttggcaaa cgtttcccga agaggattcc gactccccgc 2250

 agtttcgaag acgggcacac acgttcagcc acccaccttc aagcacaaag 2300

 agaaagctga atttgcagga tgggagggct cagggtgtgc gttcccctct 2350

 gctgaggcag agctccagtg aacagtgcag caatctttcg tcagttcgac 2400

 gcatgtacaa ggagagtaat tcttcctcca gtcttccaag tcttcacact 2450

 tccttctctg ccccttcctt cactgccccc tctttcctga aaagctttta 2500

 ccagaattca ggtagactgt ccccacagta tgaaaatgaa atcagacaag 2550

 acactgcttc agaatcaagt gatggagaag ggagaaaaag gacctcatct 2600

 acctgcagca atgagtccct aagtgtggga ggaacctctg tcactcctcg 2650

 ccggatctcc tggcggcagc gcattttcct cagggttgct tctcccatga 2700

 acaaatctcc ctcagcaatg caacagcaag atggattgga caggaacgag 2750

 ctgctgccac tgtcccccct ctctccaacc atggaggagg aaccgctggt 2800

 tatattcctg tctggggagg atgacccaga aaagattgaa gaaagaaaga 2850

 aatcaaaaga actgaggagc ttgtggagaa aagctataca ccaacaaatc 2900

 ttgttacttc gaatggaaaa agaaaaccag aaacttgaag gagcaagcag 2950

 agatgaactc cagtccagaa aagttaaatt agactatgaa gaagttggtg 3000

 catgtcagaa agaggtctta ataacttggg ataagaagtt gttaaactgc 3050

 agagctaaaa tcagatgtga tatggaagat attcatactc ttcttaaaga 3100

 aggagttccc aaaagtcgac gaggagaaat ttggcagttt ctggctttac 3150

 agtaccgact cagacacaga ttgcctaata aacaacagcc tcctgacata 3200

 tcctataagg aacttttgaa gcagctcact gctcagcagc atgcgattct 3250

 cgtggattta ggaaggacgt ttcctactca cccttacttt tcagtacagc 3300

 ttgggccagg acagctgtca ctgtttaacc tcctgaaagc ctattctttg 3350

 ctggacaaag aagtgggata ctgtcagggg atcagctttg tggctggagt 3400

 cctgcttctg cacatgagtg aagagcaagc ctttgaaatg ctgaaattcc 3450

 tcatgtatga cctcggcttc cgcaagcagt acagacctga catgatgtcg 3500

 ctgcagattc aaatgtacca gctgtccagg ctccttcatg actatcacag 3550

 agatctctac aatcaccttg aagaaaatga aatcagcccc agtctttatg 3600

 ctgccccctg gttcctcaca ttgtttgcct ctcagttttc attaggattt 3650

 gtagccagag tttttgatat tatttttctt cagggaactg aagttatatt 3700

 caaggttgca ctcagcctac tgagcagcca agagacactt ataatggaat 3750

 gtgagagctt tgaaaatatt gttgagtttc ttaaaaacac gctacctgat 3800

 atgaatacct ctgaaatgga aaaaattatt acccaggttt ttgagatgga 3850

 tatttctaag cagttgcatg cctatgaggt ggaatatcat gtgctacagg 3900

 atgagcttca ggaatcttca tattcctgtg aggatagtga aactttggag 3950

 aagctggaga gggccaatag ccaactgaaa agacaaaaca tggacctcct 4000

 agaaaaatta caggtagctc atactaaaat ccaggccttg gaatcaaacc 4050

 tggaaaatct tttgacgaga gagaccaaaa tgaagtcttt aatccggacc 4100

 ctggaacaag aaaaaatggc ttatcaaaag acagtggagc aactccggaa 4150

 gctgctgccc gcggatgctc tagccaattg tgacctgttg ctgagagacc 4200

 taaactgcaa ccctaacaac aaagccaaga taggaaataa gccataattg 4250

 aagaggcacg gcctcagcag aaagtgctcc ttagaatact acagagagga 4300

 agagcctgca tgtcgctggc ccaaggctgg accctgaagc tgatggaacc 4350

 acctaatact ggtgctgagc tcctagtcac agcaggtgga cctcgtgctc 4400

 atcagagcat gccaatccta agccattgga catatgtaga ctggtttttg 4450

 ttgttgctat gtacatataa atatatatat aaaatgaaca tagttcatgc 4500

 tttcagataa aatgagtaga tgtatattta gattaatttt tttagtcaga 4550

 acttcatgaa atccacacca aaggaaaggt aaactgaaat ttcccttgga 4600

 catatgtgaa atctttttgt ctttatagtg aaacaaagcc agagcatctt 4650

 tgtatattgc aatatacttg aaaaaaatga atgtattttt ttctccaaag 4700

 aacagcatgt ttcactcaat ggtgaaaagg tggaaacatt tatgtaactt 4750

 tatgtgtatc tgtcttgata tctactgaca ttgtctatat gaggaaaatg 4800

 attactggtc atgctcctgt gagttttttg ggaaggtagg gtcatttctc 4850

 cctgcctgct ttgtgccaac tagcatgttg catctacatg cattatgagt 4900

 ctggttaggc attactttaa acatacataa agagacagta ggacattgtg 4950

 gctgagtcta cccagctcaa ggtaaaggag aatgttgcta attttttagc 5000

 aaactagacc agcattatta ctcaaactaa aaatatcaca cctgaaaaat 5050

 ttaatttagg acctaaaatg tctagattag ctttctgctt tttttatttg 5100

 aataactcat tcagttgtga atgaattcct ctttatttgg tgccacagtc 5150

 accaaatgac aaggatttgc cactttccca ccaaattgtg agtgcttgta 5200

 atttaggtct ctctacctta aattcagtat aaggaaacgt aattatgatt 5250

 gattttttcc aaagatgaca agctgtgttg aaatacattt tttcttttga 5300

 ccaattgaca gaatctaata agctttaata atcttcccct tttatgtgaa 5350

 aagttttgag aactgtgaaa tgtttaggaa caaactgttg aaatccattg 5400

 gaagggaaaa aagaaagtgg taccagtgtt accagctcaa ctaaaacctg 5450

 caattctgca tttcaactct tcacttcctc agcctacaaa tagctcatta 5500

 gatgacattc acgcatgctg ggtataggca aggaaagtaa ttttcaaagt 5550

 acatttgcag ttctcttttt cagagatgat tctatgatag tgcctctgaa 5600

 agttgatgca gcatttttgc ctttccaaaa agtatttatc ctcactgctt 5650

 tttgcagtac ttgtattttc acagatggat tatctggggt aattttcttc 5700

 aaagggagtt tgttatacac agtgaaaatg tattatagag tagaatagta 5750

 aagctctagg ggtttcagaa agctttgatg aacagatgac aaacatctga 5800

 aaccccctcc gcactgttac ccagtgtgta tataatgact tgttatagct 5850

 cagtgtgccc ttgaatccat acagtttctt aaaagacaat aaaatcttat 5900

 taataaagtt aatgtaactt ct 5922

<210> 872
<211> 1299
<212> PRT
<213> Homo sapien

<400> 872
 Met Glu Pro Pro Ser Cys Ile Gln Asp Glu Pro Phe Pro His Pro
   1               5                  10                  15

 Leu Glu Pro Glu Pro Gly Val Ser Ala Gln Pro Gly Pro Gly Lys
                  20                  25                  30

 Pro Ser Asp Lys Arg Phe Arg Leu Trp Tyr Val Gly Gly Ser Cys
                  35                  40                  45

 Leu Asp His Arg Thr Thr Leu Pro Met Leu Pro Trp Leu Met Ala
                  50                  55                  60

 Glu Ile Arg Arg Arg Ser Gln Lys Pro Glu Ala Gly Gly Cys Gly
                  65                  70                  75

 Ala Pro Ala Ala Arg Glu Val Ile Leu Val Leu Ser Ala Pro Phe
                  80                  85                  90

 Leu Arg Cys Val Pro Ala Pro Gly Ala Gly Ala Ser Gly Gly Thr
                  95                 100                 105

 Ser Pro Ser Ala Thr Gln Pro Asn Pro Ala Val Phe Ile Phe Glu
                 110                 115                 120

 His Lys Ala Gln His Ile Ser Arg Phe Ile His Asn Ser His Asp
                 125                 130                 135

 Leu Thr Tyr Phe Ala Tyr Leu Ile Lys Ala Gln Pro Asp Asp Pro
                 140                 145                 150

 Glu Ser Gln Met Ala Cys His Val Phe Arg Ala Thr Asp Pro Ser
                 155                 160                 165

 Gln Val Pro Asp Val Ile Ser Ser Ile Arg Gln Leu Ser Lys Ala
                 170                 175                 180

 Ala Met Lys Glu Asp Ala Lys Pro Ser Lys Asp Asn Glu Asp Ala
                 185                 190                 195

 Phe Tyr Asn Ser Gln Lys Phe Glu Val Leu Tyr Cys Gly Lys Val
                 200                 205                 210

 Thr Val Thr His Lys Lys Ala Pro Ser Ser Leu Ile Asp Asp Cys
                 215                 220                 225

 Met Glu Lys Phe Ser Leu His Glu Gln Gln Arg Leu Lys Ile Gln
                 230                 235                 240

 Gly Glu Gln Arg Gly Pro Asp Pro Gly Glu Asp Leu Ala Asp Leu
                 245                 250                 255

 Glu Val Val Val Pro Gly Ser Pro Gly Asp Cys Leu Pro Glu Glu
                 260                 265                 270

 Ala Asp Gly Thr Asp Thr His Leu Gly Leu Pro Ala Gly Ala Ser
                 275                 280                 285

 Gln Pro Ala Leu Thr Ser Ser Arg Val Cys Phe Pro Glu Arg Ile
                 290                 295                 300

 Leu Glu Asp Ser Gly Phe Asp Glu Gln Gln Glu Phe Arg Ser Arg
                 305                 310                 315

 Cys Ser Ser Val Thr Gly Val Gln Arg Arg Val His Glu Gly Ser
                 320                 325                 330

 Gln Lys Ser Gln Pro Arg Arg Arg His Ala Ser Ala Pro Ser His
                 335                 340                 345

 Val Gln Pro Ser Asp Ser Glu Lys Asn Arg Thr Met Leu Phe Gln
                 350                 355                 360

 Val Gly Arg Phe Glu Ile Asn Leu Ile Ser Pro Asp Thr Lys Ser
                 365                 370                 375

 Val Val Leu Glu Lys Asn Phe Lys Asp Ile Ser Ser Cys Ser Gln
                 380                 385                 390

 Gly Ile Lys His Val Asp His Phe Gly Phe Ile Cys Arg Glu Ser
                 395                 400                 405

 Pro Glu Pro Gly Leu Ser Gln Tyr Ile Cys Tyr Val Phe Gln Cys
                 410                 415                 420

 Ala Ser Glu Ser Leu Val Asp Glu Val Met Leu Thr Leu Lys Gln
                 425                 430                 435

 Ala Phe Ser Thr Ala Ala Ala Leu Gln Ser Ala Lys Thr Gln Ile
                 440                 445                 450

 Lys Leu Cys Glu Ala Cys Pro Met His Ser Leu His Lys Leu Cys
                 455                 460                 465

 Glu Arg Ile Glu Gly Leu Tyr Pro Pro Arg Ala Lys Leu Val Ile
                 470                 475                 480

 Gln Arg His Leu Ser Ser Leu Thr Asp Asn Glu Gln Ala Asp Ile
                 485                 490                 495

 Phe Glu Arg Val Gln Lys Met Lys Pro Val Ser Asp Gln Glu Glu
                 500                 505                 510

 Asn Glu Leu Val Ile Leu His Leu Arg Gln Leu Cys Glu Ala Lys
                 515                 520                 525

 Gln Lys Thr His Val His Ile Gly Glu Gly Pro Ser Thr Ile Ser
                 530                 535                 540

 Asn Ser Thr Ile Pro Glu Asn Ala Thr Ser Ser Gly Arg Phe Lys
                 545                 550                 555

 Leu Asp Ile Leu Lys Asn Lys Ala Lys Arg Ser Leu Thr Ser Ser
                 560                 565                 570

 Leu Glu Asn Ile Phe Ser Arg Gly Ala Asn Arg Met Arg Gly Arg
                 575                 580                 585

 Leu Gly Ser Val Asp Ser Phe Glu Arg Ser Asn Ser Leu Ala Ser
                 590                 595                 600

 Glu Lys Asp Tyr Ser Pro Gly Asp Ser Pro Pro Gly Thr Pro Pro
                 605                 610                 615

 Ala Ser Pro Pro Ser Ser Ala Trp Gln Thr Phe Pro Glu Glu Asp
                 620                 625                 630

 Ser Asp Ser Pro Gln Phe Arg Arg Arg Ala His Thr Phe Ser His
                 635                 640                 645

 Pro Pro Ser Ser Thr Lys Arg Lys Leu Asn Leu Gln Asp Gly Arg
                 650                 655                 660

 Ala Gln Gly Val Arg Ser Pro Leu Leu Arg Gln Ser Ser Ser Glu
                 665                 670                 675

 Gln Cys Ser Asn Leu Ser Ser Val Arg Arg Met Tyr Lys Glu Ser
                 680                 685                 690

 Asn Ser Ser Ser Ser Leu Pro Ser Leu His Thr Ser Phe Ser Ala
                 695                 700                 705

 Pro Ser Phe Thr Ala Pro Ser Phe Leu Lys Ser Phe Tyr Gln Asn
                 710                 715                 720

 Ser Gly Arg Leu Ser Pro Gln Tyr Glu Asn Glu Ile Arg Gln Asp
                 725                 730                 735

 Thr Ala Ser Glu Ser Ser Asp Gly Glu Gly Arg Lys Arg Thr Ser
                 740                 745                 750

 Ser Thr Cys Ser Asn Glu Ser Leu Ser Val Gly Gly Thr Ser Val
                 755                 760                 765

 Thr Pro Arg Arg Ile Ser Trp Arg Gln Arg Ile Phe Leu Arg Val
                 770                 775                 780

 Ala Ser Pro Met Asn Lys Ser Pro Ser Ala Met Gln Gln Gln Asp
                 785                 790                 795

 Gly Leu Asp Arg Asn Glu Leu Leu Pro Leu Ser Pro Leu Ser Pro
                 800                 805                 810

 Thr Met Glu Glu Glu Pro Leu Val Ile Phe Leu Ser Gly Glu Asp
                 815                 820                 825

 Asp Pro Glu Lys Ile Glu Glu Arg Lys Lys Ser Lys Glu Leu Arg
                 830                 835                 840

 Ser Leu Trp Arg Lys Ala Ile His Gln Gln Ile Leu Leu Leu Arg
                 845                 850                 855

 Met Glu Lys Glu Asn Gln Lys Leu Glu Gly Ala Ser Arg Asp Glu
                 860                 865                 870

 Leu Gln Ser Arg Lys Val Lys Leu Asp Tyr Glu Glu Val Gly Ala
                 875                 880                 885

 Cys Gln Lys Glu Val Leu Ile Thr Trp Asp Lys Lys Leu Leu Asn
                 890                 895                 900

 Cys Arg Ala Lys Ile Arg Cys Asp Met Glu Asp Ile His Thr Leu
                 905                 910                 915

 Leu Lys Glu Gly Val Pro Lys Ser Arg Arg Gly Glu Ile Trp Gln
                 920                 925                 930

 Phe Leu Ala Leu Gln Tyr Arg Leu Arg His Arg Leu Pro Asn Lys
                 935                 940                 945

 Gln Gln Pro Pro Asp Ile Ser Tyr Lys Glu Leu Leu Lys Gln Leu
                 950                 955                 960

 Thr Ala Gln Gln His Ala Ile Leu Val Asp Leu Gly Arg Thr Phe
                 965                 970                 975

 Pro Thr His Pro Tyr Phe Ser Val Gln Leu Gly Pro Gly Gln Leu
                 980                 985                 990

 Ser Leu Phe Asn Leu Leu Lys Ala Tyr Ser Leu Leu Asp Lys Glu
                 995                1000                1005

 Val Gly Tyr Cys Gln Gly Ile Ser Phe Val Ala Gly Val Leu Leu
                1010                1015                1020

 Leu His Met Ser Glu Glu Gln Ala Phe Glu Met Leu Lys Phe Leu
                1025                1030                1035

 Met Tyr Asp Leu Gly Phe Arg Lys Gln Tyr Arg Pro Asp Met Met
                1040                1045                1050

 Ser Leu Gln Ile Gln Met Tyr Gln Leu Ser Arg Leu Leu His Asp
                1055                1060                1065

 Tyr His Arg Asp Leu Tyr Asn His Leu Glu Glu Asn Glu Ile Ser
                1070                1075                1080

 Pro Ser Leu Tyr Ala Ala Pro Trp Phe Leu Thr Leu Phe Ala Ser
                1085                1090                1095

 Gln Phe Ser Leu Gly Phe Val Ala Arg Val Phe Asp Ile Ile Phe
                1100                1105                1110

 Leu Gln Gly Thr Glu Val Ile Phe Lys Val Ala Leu Ser Leu Leu
                1115                1120                1125

 Ser Ser Gln Glu Thr Leu Ile Met Glu Cys Glu Ser Phe Glu Asn
                1130                1135                1140

 Ile Val Glu Phe Leu Lys Asn Thr Leu Pro Asp Met Asn Thr Ser
                1145                1150                1155

 Glu Met Glu Lys Ile Ile Thr Gln Val Phe Glu Met Asp Ile Ser
                1160                1165                1170

 Lys Gln Leu His Ala Tyr Glu Val Glu Tyr His Val Leu Gln Asp
                1175                1180                1185

 Glu Leu Gln Glu Ser Ser Tyr Ser Cys Glu Asp Ser Glu Thr Leu
                1190                1195                1200

 Glu Lys Leu Glu Arg Ala Asn Ser Gln Leu Lys Arg Gln Asn Met
                1205                1210                1215

 Asp Leu Leu Glu Lys Leu Gln Val Ala His Thr Lys Ile Gln Ala
                1220                1225                1230

 Leu Glu Ser Asn Leu Glu Asn Leu Leu Thr Arg Glu Thr Lys Met
                1235                1240                1245

 Lys Ser Leu Ile Arg Thr Leu Glu Gln Glu Lys Met Ala Tyr Gln
                1250                1255                1260

 Lys Thr Val Glu Gln Leu Arg Lys Leu Leu Pro Ala Asp Ala Leu
                1265                1270                1275

 Ala Asn Cys Asp Leu Leu Leu Arg Asp Leu Asn Cys Asn Pro Asn
                1280                1285                1290

 Asn Lys Ala Lys Ile Gly Asn Lys Pro
                1295

<210> 873
<211> 1941
<212> DNA
<213> Homo sapien

<400> 873
 aatgtccccg cgtgtctgct aggagagggc gggcagcgcc gcggcgcgcg 50

 cgatccggct gacgcatctg gccccggttc cccaagacca gagcggggcc 100

 gggagggagg gggaagaggc gagagcgcgg agggcgcgcg tgcgcattgg 150

 cgcggggagg agcagggatc ttggcagcgg gcgaggaggc tgcgagcgag 200

 ccgcgaaccg agcgggcggc gggcgcgcgc accatggggg agaaacccgg 250

 gaccagggtc ttcaagaagt cgagccctaa ctgcaagctc accgtgtact 300

 tgggcaagcg ggacttcgta gatcacctgg acaaagtgga ccctgtagat 350

 ggcgtggtgc ttgtggaccc tgactacctg aaggaccgca aagtgtttgt 400

 gaccctcacc tgcgccttcc gctatggccg tgaagacctg gatgtgctgg 450

 gcttgtcctt ccgcaaagac ctgttcatcg ccacctacca ggccttcccc 500

 ccggtgccca acccaccccg gccccccacc cgcctgcagg accggctgct 550

 gaggaagctg ggccagcatg cccacccctt cttcttcacc ataccccaga 600

 atcttccatg ctccgtcaca ctgcagccag gcccagagga tacaggaaag 650

 gcctgcggcg tagactttga gattcgagcc ttctgtgcta aatcactaga 700

 agagaaaagc cacaaaagga actctgtgcg gctggtgatc cgaaaggtgc 750

 agttcgcccc ggagaaaccc ggcccccagc cttcagccga aaccacacgc 800

 cacttcctca tgtctgaccg gtccctgcac ctcgaggctt ccctggacaa 850

 ggagctgtac taccatgggg agcccctcaa tgtaaatgtc cacgtcacca 900

 acaactccac caagaccgtc aagaagatca aagtctctgt gagacagtac 950

 gccgacatct gcctcttcag caccgcccag tacaagtgtc ctgtggctca 1000

 actcgaacaa gatgaccagg tatctcccag ctccacattc tgtaaggtgt 1050

 acaccataac cccactgctc agtgacaacc gggagaagcg gggtctcgcc 1100

 ctggatggga aactcaagca cgaggacacc aacctggctt ccagcaccat 1150

 cgtgaaggag ggtgccaaca aggaggtgct gggaatcctg gtgtcctaca 1200

 gggtcaaggt gaagctggtg gtgtctcgag gcggggatgt ctctgtggag 1250

 ctgccttttg ttcttatgca ccccaagccc cacgaccaca tccccctccc 1300

 cagaccccag tcagccgctc cggagacaga tgtccctgtg gacaccaacc 1350

 tcattgaatt tgataccaac tatgccacag atgatgacat tgtgtttgag 1400

 gactttgccc ggcttcggct gaaggggatg aaggatgacg actatgatga 1450

 tcaactctgc taggaagcgg ggtgggaaga agggagggga tggggttggg 1500

 agaggtgagg gcaggattaa gatccccact gtcaatgggg gattgtccca 1550

 gcccctcttc ccttcccctc acctggaagc ttcttcaacc aatcccttca 1600

 cactctctcc cccatccccc caagatacac actggaccct ctcttgctga 1650

 atgtgggcat taattttttg actgcagttc tgcttctcca gccccgccgt 1700

 gggtggcaag ctgtgttcat acctaaattt tctggaaggg gacagtgaaa 1750

 agaggagtga caggagggaa agggggagac aaaactccta ctctcaacct 1800

 cacaccaaca cctcccatta tcactctctc tgcccccatt ccttcaagag 1850

 gagacccttt ggggacaagg ccgtttcttt gtttctgagc ataaagaaga 1900

 aaataaatct tttactaagc atgaaaaaaa aaaaaaaaaa a 1941

<210> 874
<211> 409
<212> PRT
<213> Homo sapien

<400> 874
 Met Gly Glu Lys Pro Gly Thr Arg Val Phe Lys Lys Ser Ser Pro
   1               5                  10                  15

 Asn Cys Lys Leu Thr Val Tyr Leu Gly Lys Arg Asp Phe Val Asp
                  20                  25                  30

 His Leu Asp Lys Val Asp Pro Val Asp Gly Val Val Leu Val Asp
                  35                  40                  45

 Pro Asp Tyr Leu Lys Asp Arg Lys Val Phe Val Thr Leu Thr Cys
                  50                  55                  60

 Ala Phe Arg Tyr Gly Arg Glu Asp Leu Asp Val Leu Gly Leu Ser
                  65                  70                  75

 Phe Arg Lys Asp Leu Phe Ile Ala Thr Tyr Gln Ala Phe Pro Pro
                  80                  85                  90

 Val Pro Asn Pro Pro Arg Pro Pro Thr Arg Leu Gln Asp Arg Leu
                  95                 100                 105

 Leu Arg Lys Leu Gly Gln His Ala His Pro Phe Phe Phe Thr Ile
                 110                 115                 120

 Pro Gln Asn Leu Pro Cys Ser Val Thr Leu Gln Pro Gly Pro Glu
                 125                 130                 135

 Asp Thr Gly Lys Ala Cys Gly Val Asp Phe Glu Ile Arg Ala Phe
                 140                 145                 150

 Cys Ala Lys Ser Leu Glu Glu Lys Ser His Lys Arg Asn Ser Val
                 155                 160                 165

 Arg Leu Val Ile Arg Lys Val Gln Phe Ala Pro Glu Lys Pro Gly
                 170                 175                 180

 Pro Gln Pro Ser Ala Glu Thr Thr Arg His Phe Leu Met Ser Asp
                 185                 190                 195

 Arg Ser Leu His Leu Glu Ala Ser Leu Asp Lys Glu Leu Tyr Tyr
                 200                 205                 210

 His Gly Glu Pro Leu Asn Val Asn Val His Val Thr Asn Asn Ser
                 215                 220                 225

 Thr Lys Thr Val Lys Lys Ile Lys Val Ser Val Arg Gln Tyr Ala
                 230                 235                 240

 Asp Ile Cys Leu Phe Ser Thr Ala Gln Tyr Lys Cys Pro Val Ala
                 245                 250                 255

 Gln Leu Glu Gln Asp Asp Gln Val Ser Pro Ser Ser Thr Phe Cys
                 260                 265                 270

 Lys Val Tyr Thr Ile Thr Pro Leu Leu Ser Asp Asn Arg Glu Lys
                 275                 280                 285

 Arg Gly Leu Ala Leu Asp Gly Lys Leu Lys His Glu Asp Thr Asn
                 290                 295                 300

 Leu Ala Ser Ser Thr Ile Val Lys Glu Gly Ala Asn Lys Glu Val
                 305                 310                 315

 Leu Gly Ile Leu Val Ser Tyr Arg Val Lys Val Lys Leu Val Val
                 320                 325                 330

 Ser Arg Gly Gly Asp Val Ser Val Glu Leu Pro Phe Val Leu Met
                 335                 340                 345

 His Pro Lys Pro His Asp His Ile Pro Leu Pro Arg Pro Gln Ser
                 350                 355                 360

 Ala Ala Pro Glu Thr Asp Val Pro Val Asp Thr Asn Leu Ile Glu
                 365                 370                 375

 Phe Asp Thr Asn Tyr Ala Thr Asp Asp Asp Ile Val Phe Glu Asp
                 380                 385                 390

 Phe Ala Arg Leu Arg Leu Lys Gly Met Lys Asp Asp Asp Tyr Asp
                 395                 400                 405

 Asp Gln Leu Cys


<210> 875
<211> 550
<212> DNA
<213> Homo sapien

<400> 875
 ggccggggtt gactccgggg gcgcggcgag gagagacatg aggctgagct 50

 ggttccgggt cctgacagta ctgtccatct gcctgagcgc cgtggccagc 100

 acggggaccg agggcaaaag gaagctgcag atcggggtca agaagcgggt 150

 ggaccactgt cccatcaaat cgcgcaaagg ggatgtcctg cacatgcact 200

 acacggggaa gctggaagat gggacagagt ttgacagcag cctgccccag 250

 aaccagccct ttgtcttctc ccttggcaca ggccaggtca tcaagggctg 300

 ggaccagggg ctgctgggga tgtatgaggg ggaaaagcgc aagctggtga 350

 tcccatccga gctagggtat ggagagcggg gagctccccc aaagattcca 400

 ggcggtgcaa ccctggtgtt cgaggtggag ctgctcaaaa tagagcgacg 450

 aactgagctg taaccagact gggaggggca ggggagaggc ccccatcagg 500

 accagactgt tccaaaaaaa aaaaaacaaa aaacaaacaa aaaaacactt 550

<210> 876
<211> 141
<212> PRT
<213> Homo sapien

<400> 876
 Met Arg Leu Ser Trp Phe Arg Val Leu Thr Val Leu Ser Ile Cys
   1               5                  10                  15

 Leu Ser Ala Val Ala Ser Thr Gly Thr Glu Gly Lys Arg Lys Leu
                  20                  25                  30

 Gln Ile Gly Val Lys Lys Arg Val Asp His Cys Pro Ile Lys Ser
                  35                  40                  45

 Arg Lys Gly Asp Val Leu His Met His Tyr Thr Gly Lys Leu Glu
                  50                  55                  60

 Asp Gly Thr Glu Phe Asp Ser Ser Leu Pro Gln Asn Gln Pro Phe
                  65                  70                  75

 Val Phe Ser Leu Gly Thr Gly Gln Val Ile Lys Gly Trp Asp Gln
                  80                  85                  90

 Gly Leu Leu Gly Met Tyr Glu Gly Glu Lys Arg Lys Leu Val Ile
                  95                 100                 105

 Pro Ser Glu Leu Gly Tyr Gly Glu Arg Gly Ala Pro Pro Lys Ile
                 110                 115                 120

 Pro Gly Gly Ala Thr Leu Val Phe Glu Val Glu Leu Leu Lys Ile
                 125                 130                 135

 Glu Arg Arg Thr Glu Leu
                 140

<210> 877
<211> 3874
<212> DNA
<213> Homo sapien

<400> 877
 atggctcacc taaagcgact agtaaaatta cacattaaaa gacattacca 50

 taaaaagttc tggaagcttg gtgcagtaat ttttttcttt ataatagttt 100

 tggttttaat gcaaagagaa gtaagtgttc aatattccaa agaggaatca 150

 aggatggaaa ggaacatgaa aaacaaaaac aagatgttgg atttaatgct 200

 agaagctgta aacaatatta aggatgccat gccaaaaatg caaataggag 250

 cacctgtcag gcaaaacatt gatgctggtg agagaccttg tttgcaagga 300

 tattatacag cagcagaatt gaagcctgtc cttgaccgtc cacctcagga 350

 ttcaaatgca cctggtgctt ctggtaaagc attcaagaca accaatttaa 400

 gtgttgaaga gcaaaaggaa aaggaacgtg gggaagctaa acactgcttt 450

 aatgctttcg caagtgacag gatttctttg caccgagatc ttggaccaga 500

 cactcgacct cctgaatgta ttgaacaaaa atttaagcgc tgccctcccc 550

 tgcccaccac cagtgtcata atagtttttc ataatgaagc gtggtccacg 600

 ttgcttagaa ctgtccacag tgtgctctat tcttcacctg caatactgct 650

 gaaggaaatc attttggtgg atgatgctag tgtagatgag tacttacatg 700

 ataaactaga tgaatatgta aaacaatttt ctatagtaaa aatagtcaga 750

 caaagagaaa gaaaaggtct gatcactgct cggttgctag gagcaacagt 800

 cgcaacagct gaaacgctca catttttaga tgctcactgt gagtgtttct 850

 atggttggct agaacctctg ttggccagaa tagctgagaa ctacacggct 900

 gtcgtaagtc cagatattgc atccatagat ctgaacacgt ttgaattcaa 950

 caaaccttct ccttatggaa gtaaccataa ccgtggaaat tttgactgga 1000

 gtctttcatt tggctgggag tcgcttcctg atcatgagaa gcaaagaagg 1050

 aaagatgaaa cctacccaat taaaacaccc acttttgcag gaggactttt 1100

 ttccatatca aaagaatatt ttgagtatat tggaagctat gatgaagaaa 1150

 tggaaatctg gggaggtgaa aatatagaaa tgtctttcag agtatggcaa 1200

 tgtggtgggc agttggagat tatgccttgc tctgttgttg gacatgtttt 1250

 tcgcagcaaa agccctcata gctttccaaa aggcactcag gtgattgcta 1300

 gaaaccaagt tcgccttgca gaagtctgga tggatgaata caaggaaata 1350

 ttttatagga gaaatacaga tgcagcaaaa attgttaaac aaaaagcatt 1400

 tggtgatctt tcaaaaagat ttgaaataaa acaccgtctt cggtgtaaaa 1450

 attttacatg gtatctgaac aacatttatc cagaggtgta tgtgccagac 1500

 cttaatcctg ttatatctgg atacattaaa agcgttggtc agcctctatg 1550

 tctggatgtt ggagaaaaca atcaaggagg caaaccatta attatgtata 1600

 catgtcatgg acttggggga aaccagtact ttgaatactc tgctcaacat 1650

 gaaattcggc acaacatcca gaaggaatta tgtcttcatg ctgctcaagg 1700

 tctcgttcag ctgaaggcat gtacctacaa aggtcacaag acagttgtca 1750

 ctggagagca gatatgggag atccagaagg atcaacttct atacaatcca 1800

 ttcttaaaaa tgtgcctttc agcaaatgga gagcatccaa gtttagtgtc 1850

 atgcaaccca tcagatccac tccaaaaatg gatacttagc caaaatgatt 1900

 aagtgttcct taaaattaag ttgaaaaagg aaatattctt tctcataaaa 1950

 ctgtgactag gcatacactg tagtttttga aaattatgca aaagcagcta 2000

 aatgtaactt attccaagtg catttttctt atttatatct ttatgtagca 2050

 ctactacaga aattctgcaa gtttctgttt caaagcacaa taactagtaa 2100

 taccaaagac tatttcaaaa tgtccagatg taggggaaga gatgtttaca 2150

 gtatgatgaa aataattttc caagtaaagt gatgtttgtg tgttttgtac 2200

 acttagggat atatatatat agctacattc acacactcac aatttaaaat 2250

 atttccccta gttttttggg gggataggaa gaaagatttg ttactgtatt 2300

 tttttaacta cataaaaata gatcaataaa tgtcagcatt ggcctctgtg 2350

 tacaaaccaa gagcttttac agatccagaa tttattagtt taaaatgcag 2400

 gtgaactttt ttttgcgttt ggtttacttg tctgtcaaat gtttccttaa 2450

 acatgaaact gaataaggag aagagtattt ttaacactta aatttcttgg 2500

 caaattttaa aacatttttt agtctgtaat acactccact tgaagcactt 2550

 aagtcttcct taaatgactt ttcttaagta atgatactgt gtgttttccc 2600

 aaagcacttt taaaaaaatt tttataaatt actatctgtt gaaaaggtgt 2650

 ccttttcctt tcttctagta ttttttttct taccaaaatt cactaatctt 2700

 gaatgtttgt gatattaaat ttcaaatgca gaatacttga ctcatttaaa 2750

 gctaaatttt gttactgatt caattataat tgtaatggat ttttgacttt 2800

 gtaatggatt cttttcatca aaaagcctta ttatttttta tctatgtgga 2850

 aaacacaata aaaaatcctc aacactattg taatcatttg gttaagtgct 2900

 tattcctctt ttgggtaaaa tctgtaattg ataataggtg ggggaaaatg 2950

 aattttgtat gctgaatttc taagcgccta ttgtttgtaa aaccatcaga 3000

 tatttcttat ggcacaaaaa atgaggaata gcaaaattcc tgtgttcaat 3050

 atttagaaaa ttttgtatta atttctgata aagttcctta agcatctgat 3100

 agaatgatgt tttaaaaaaa tttgacgctt gcttaggaga tttaccactt 3150

 tttttttttg tttttcgtca ttttatattt agatctcctg tattcttgtt 3200

 cccgaagtaa aatacgatcg gtttcatatt ttaaatctgg cagagcctca 3250

 gctgtacgaa aaagagcata tactggttat tgaccctatc ttctcattgt 3300

 ttgtttgtaa gtttgaattt gtattaaaaa gcctgcattc tgagctggac 3350

 atggtggctc agcttctaat cccagcactt tggtaggcaa aggtgggagg 3400

 atcatttgag ctcaggagtt ccagaccagc ctgggcaaca tagcaaaatc 3450

 tcatctctac aaaaagtaaa aattaaaaaa tgaaattaaa aataaaatta 3500

 cctaggtgtg gtggcacgca tctgtagttc cagctataca ggaaggtgag 3550

 gcagaagcat tgcttgagct tgggagatcg aggctacagt gagctatgat 3600

 tacaccactg cacttcagtc tgtgtgactg agcaagactc tttcaaaaaa 3650

 aaaaaaaagc ctacattctc cagttgatta tttccaacta atgtgtatta 3700

 tgtgcctaat tttctatcag aagttgtatt aagcccgttt tcacactgct 3750

 gttaaagaca tacctgagac tgggtaattt ataaagaaaa ataggttcaa 3800

 tggacccaca ggtccgcgtg gctggggaag cttcacaatc atggcggaag 3850

 gtgaaagcat gtcttacgtg gaag 3874

<210> 878
<211> 633
<212> PRT
<213> Homo sapien

<400> 878
 Met Ala His Leu Lys Arg Leu Val Lys Leu His Ile Lys Arg His
   1               5                  10                  15

 Tyr His Lys Lys Phe Trp Lys Leu Gly Ala Val Ile Phe Phe Phe
                  20                  25                  30

 Ile Ile Val Leu Val Leu Met Gln Arg Glu Val Ser Val Gln Tyr
                  35                  40                  45

 Ser Lys Glu Glu Ser Arg Met Glu Arg Asn Met Lys Asn Lys Asn
                  50                  55                  60

 Lys Met Leu Asp Leu Met Leu Glu Ala Val Asn Asn Ile Lys Asp
                  65                  70                  75

 Ala Met Pro Lys Met Gln Ile Gly Ala Pro Val Arg Gln Asn Ile
                  80                  85                  90

 Asp Ala Gly Glu Arg Pro Cys Leu Gln Gly Tyr Tyr Thr Ala Ala
                  95                 100                 105

 Glu Leu Lys Pro Val Leu Asp Arg Pro Pro Gln Asp Ser Asn Ala
                 110                 115                 120

 Pro Gly Ala Ser Gly Lys Ala Phe Lys Thr Thr Asn Leu Ser Val
                 125                 130                 135

 Glu Glu Gln Lys Glu Lys Glu Arg Gly Glu Ala Lys His Cys Phe
                 140                 145                 150

 Asn Ala Phe Ala Ser Asp Arg Ile Ser Leu His Arg Asp Leu Gly
                 155                 160                 165

 Pro Asp Thr Arg Pro Pro Glu Cys Ile Glu Gln Lys Phe Lys Arg
                 170                 175                 180

 Cys Pro Pro Leu Pro Thr Thr Ser Val Ile Ile Val Phe His Asn
                 185                 190                 195

 Glu Ala Trp Ser Thr Leu Leu Arg Thr Val His Ser Val Leu Tyr
                 200                 205                 210

 Ser Ser Pro Ala Ile Leu Leu Lys Glu Ile Ile Leu Val Asp Asp
                 215                 220                 225

 Ala Ser Val Asp Glu Tyr Leu His Asp Lys Leu Asp Glu Tyr Val
                 230                 235                 240

 Lys Gln Phe Ser Ile Val Lys Ile Val Arg Gln Arg Glu Arg Lys
                 245                 250                 255

 Gly Leu Ile Thr Ala Arg Leu Leu Gly Ala Thr Val Ala Thr Ala
                 260                 265                 270

 Glu Thr Leu Thr Phe Leu Asp Ala His Cys Glu Cys Phe Tyr Gly
                 275                 280                 285

 Trp Leu Glu Pro Leu Leu Ala Arg Ile Ala Glu Asn Tyr Thr Ala
                 290                 295                 300

 Val Val Ser Pro Asp Ile Ala Ser Ile Asp Leu Asn Thr Phe Glu
                 305                 310                 315

 Phe Asn Lys Pro Ser Pro Tyr Gly Ser Asn His Asn Arg Gly Asn
                 320                 325                 330

 Phe Asp Trp Ser Leu Ser Phe Gly Trp Glu Ser Leu Pro Asp His
                 335                 340                 345

 Glu Lys Gln Arg Arg Lys Asp Glu Thr Tyr Pro Ile Lys Thr Pro
                 350                 355                 360

 Thr Phe Ala Gly Gly Leu Phe Ser Ile Ser Lys Glu Tyr Phe Glu
                 365                 370                 375

 Tyr Ile Gly Ser Tyr Asp Glu Glu Met Glu Ile Trp Gly Gly Glu
                 380                 385                 390

 Asn Ile Glu Met Ser Phe Arg Val Trp Gln Cys Gly Gly Gln Leu
                 395                 400                 405

 Glu Ile Met Pro Cys Ser Val Val Gly His Val Phe Arg Ser Lys
                 410                 415                 420

 Ser Pro His Ser Phe Pro Lys Gly Thr Gln Val Ile Ala Arg Asn
                 425                 430                 435

 Gln Val Arg Leu Ala Glu Val Trp Met Asp Glu Tyr Lys Glu Ile
                 440                 445                 450

 Phe Tyr Arg Arg Asn Thr Asp Ala Ala Lys Ile Val Lys Gln Lys
                 455                 460                 465

 Ala Phe Gly Asp Leu Ser Lys Arg Phe Glu Ile Lys His Arg Leu
                 470                 475                 480

 Arg Cys Lys Asn Phe Thr Trp Tyr Leu Asn Asn Ile Tyr Pro Glu
                 485                 490                 495

 Val Tyr Val Pro Asp Leu Asn Pro Val Ile Ser Gly Tyr Ile Lys
                 500                 505                 510

 Ser Val Gly Gln Pro Leu Cys Leu Asp Val Gly Glu Asn Asn Gln
                 515                 520                 525

 Gly Gly Lys Pro Leu Ile Met Tyr Thr Cys His Gly Leu Gly Gly
                 530                 535                 540

 Asn Gln Tyr Phe Glu Tyr Ser Ala Gln His Glu Ile Arg His Asn
                 545                 550                 555

 Ile Gln Lys Glu Leu Cys Leu His Ala Ala Gln Gly Leu Val Gln
                 560                 565                 570

 Leu Lys Ala Cys Thr Tyr Lys Gly His Lys Thr Val Val Thr Gly
                 575                 580                 585

 Glu Gln Ile Trp Glu Ile Gln Lys Asp Gln Leu Leu Tyr Asn Pro
                 590                 595                 600

 Phe Leu Lys Met Cys Leu Ser Ala Asn Gly Glu His Pro Ser Leu
                 605                 610                 615

 Val Ser Cys Asn Pro Ser Asp Pro Leu Gln Lys Trp Ile Leu Ser
                 620                 625                 630

 Gln Asn Asp


<210> 879
<211> 1820
<212> DNA
<213> Homo sapien

<400> 879
 gagctccaag ctggtttgaa caagccctgg gcatgtttgg cgggaagttg 50

 gcttagctcg gctacctgtg gccccgcagt tttgtagtcc ccgccttgtt 100

 tctccccaga ggcctctcaa tcctccctcc atgatcttcg catagagcac 150

 agtacccctt cacacggagg acgcgatggc tcccaagaaa cgcccagaaa 200

 cccagaagac ctccgagatt gtattacgcc ccaggaacaa gaggagcagg 250

 agtcccctgg agctggagcc cgaggccaag aagctctgtg cgaagggctc 300

 cggtcctagc agaagatgtg actcagactg cctctgggtg gggctggctg 350

 gcccacagat cctgccacca tgccgcagca tcgtcaggac cctccaccag 400

 cataagctgg gcagagcttc ctggccatct gtccagcagg ggctccagca 450

 gtcctttttg cacactctgg attcttaccg gatattacaa aaggctgccc 500

 cctttgacag gagggctaca tccttggcgt ggcacccaac tcaccccagc 550

 accgtggctg tgggttccaa agggggagat atcatgctct ggaattttgg 600

 catcaaggac aaacccacct tcatcaaagg gattggagct ggagggagca 650

 tcactgggct gaagtttaac cctctcaata ccaaccagtt ttacgcctcc 700

 tcaatggagg gaacaactag gctgcaagac tttaaaggca acattctacg 750

 agtttttgcc agctcagaca ccatcaacat ctggttttgt agcctggatg 800

 tgtctgctag tagccgaatg gtggtcacag gagacaacgt ggggaacgtg 850

 atcctgctga acatggacgg caaagagctt tggaatctca gaatgcacaa 900

 aaagaaagtg acgcatgtgg ccctgaaccc atgctgtgat tggttcctgg 950

 ccacagcctc cgtagatcaa acagtgaaaa tttgggacct gcgccaggtt 1000

 agagggaaag ccagcttcct ctactcgctg ccgcacaggc atcctgtcaa 1050

 cgcagcttgt ttcagtcccg atggagcccg gctcctgacc acggaccaga 1100

 agagcgagat ccgagtttac tctgcttccc agtgggactg ccccctgggc 1150

 ctgatcccgc accctcaccg tcacttccag cacctcacac ccatcaaggc 1200

 agcctggcat cctcgctaca acctcattgt tgtgggccga tacccagatc 1250

 ctaatttcaa aagttgtacc ccttatgaat tgaggacgat cgacgtgttc 1300

 gatggaaact cagggaagat gatgtgtcag ctctatgacc cagaatcttc 1350

 tggcatcagt tcgcttaatg aattcaatcc catgggggac acgctggcct 1400

 ctgcaatggg ttaccacatt ctcatctgga gccaggagga agccaggaca 1450

 cggaagtgag agacactaaa gaaggtgtgg gccagacaag gccttggagc 1500

 ccacacatgg gatcaagtcc tgcaagcaga ggtggtgatt tgttaaaggg 1550

 ccaaaagtat ccaaggttag ggttggagca ggggtgctgg gacctggggc 1600

 actgtgggac tgggacactt ttatgttaat gctctggact tgcctccaga 1650

 gactgctcca gagttggtga cacagctgtc ccaagggccc ctctgtatct 1700

 agcctggaac caaggttatc ttggaactaa atgacttttc tcctctcagt 1750

 gggtggtagc agagggatca agcagttatt tgatttgtgc tcttttgata 1800

 tggccaataa aaccataccg 1820

<210> 880
<211> 427
<212> PRT
<213> Homo sapien

<400> 880
 Met Ala Pro Lys Lys Arg Pro Glu Thr Gln Lys Thr Ser Glu Ile
   1               5                  10                  15

 Val Leu Arg Pro Arg Asn Lys Arg Ser Arg Ser Pro Leu Glu Leu
                  20                  25                  30

 Glu Pro Glu Ala Lys Lys Leu Cys Ala Lys Gly Ser Gly Pro Ser
                  35                  40                  45

 Arg Arg Cys Asp Ser Asp Cys Leu Trp Val Gly Leu Ala Gly Pro
                  50                  55                  60

 Gln Ile Leu Pro Pro Cys Arg Ser Ile Val Arg Thr Leu His Gln
                  65                  70                  75

 His Lys Leu Gly Arg Ala Ser Trp Pro Ser Val Gln Gln Gly Leu
                  80                  85                  90

 Gln Gln Ser Phe Leu His Thr Leu Asp Ser Tyr Arg Ile Leu Gln
                  95                 100                 105

 Lys Ala Ala Pro Phe Asp Arg Arg Ala Thr Ser Leu Ala Trp His
                 110                 115                 120

 Pro Thr His Pro Ser Thr Val Ala Val Gly Ser Lys Gly Gly Asp
                 125                 130                 135

 Ile Met Leu Trp Asn Phe Gly Ile Lys Asp Lys Pro Thr Phe Ile
                 140                 145                 150

 Lys Gly Ile Gly Ala Gly Gly Ser Ile Thr Gly Leu Lys Phe Asn
                 155                 160                 165

 Pro Leu Asn Thr Asn Gln Phe Tyr Ala Ser Ser Met Glu Gly Thr
                 170                 175                 180

 Thr Arg Leu Gln Asp Phe Lys Gly Asn Ile Leu Arg Val Phe Ala
                 185                 190                 195

 Ser Ser Asp Thr Ile Asn Ile Trp Phe Cys Ser Leu Asp Val Ser
                 200                 205                 210

 Ala Ser Ser Arg Met Val Val Thr Gly Asp Asn Val Gly Asn Val
                 215                 220                 225

 Ile Leu Leu Asn Met Asp Gly Lys Glu Leu Trp Asn Leu Arg Met
                 230                 235                 240

 His Lys Lys Lys Val Thr His Val Ala Leu Asn Pro Cys Cys Asp
                 245                 250                 255

 Trp Phe Leu Ala Thr Ala Ser Val Asp Gln Thr Val Lys Ile Trp
                 260                 265                 270

 Asp Leu Arg Gln Val Arg Gly Lys Ala Ser Phe Leu Tyr Ser Leu
                 275                 280                 285

 Pro His Arg His Pro Val Asn Ala Ala Cys Phe Ser Pro Asp Gly
                 290                 295                 300

 Ala Arg Leu Leu Thr Thr Asp Gln Lys Ser Glu Ile Arg Val Tyr
                 305                 310                 315

 Ser Ala Ser Gln Trp Asp Cys Pro Leu Gly Leu Ile Pro His Pro
                 320                 325                 330

 His Arg His Phe Gln His Leu Thr Pro Ile Lys Ala Ala Trp His
                 335                 340                 345

 Pro Arg Tyr Asn Leu Ile Val Val Gly Arg Tyr Pro Asp Pro Asn
                 350                 355                 360

 Phe Lys Ser Cys Thr Pro Tyr Glu Leu Arg Thr Ile Asp Val Phe
                 365                 370                 375

 Asp Gly Asn Ser Gly Lys Met Met Cys Gln Leu Tyr Asp Pro Glu
                 380                 385                 390

 Ser Ser Gly Ile Ser Ser Leu Asn Glu Phe Asn Pro Met Gly Asp
                 395                 400                 405

 Thr Leu Ala Ser Ala Met Gly Tyr His Ile Leu Ile Trp Ser Gln
                 410                 415                 420

 Glu Glu Ala Arg Thr Arg Lys
                 425

<210> 881
<211> 3181
<212> DNA
<213> Homo sapien

<400> 881
 actcagtgtt cgcgggagcg ccgcacctac accagccaac ccagatcccg 50

 aggtccgaca gcgcccggcc cagatcccca cgcctgccag gagcaagccg 100

 agagccagcc ggccggcgca ctccgactcc gagcagtctc tgtccttcga 150

 cccgagcccc gcgccctttc cgggacccct gccccgcggg cagcgctgcc 200

 aacctgccgg ccatggagac cccgtcccag cggcgcgcca cccgcagcgg 250

 ggcgcaggcc agctccactc cgctgtcgcc cacccgcatc acccggctgc 300

 aggagaagga ggacctgcag gagctcaatg atcgcttggc ggtctacatc 350

 gaccgtgtgc gctcgctgga aacggagaac gcagggctgc gccttcgcat 400

 caccgagtct gaagaggtgg tcagccgcga ggtgtccggc atcaaggccg 450

 cctacgaggc cgagctcggg gatgcccgca agacccttga ctcagtagcc 500

 aaggagcgcg cccgcctgca gctggagctg agcaaagtgc gtgaggagtt 550

 taaggagctg aaagcgcgca ataccaagaa ggagggtgac ctgatagctg 600

 ctcaggctcg gctgaaggac ctggaggctc tgctgaactc caaggaggcc 650

 gcactgagca ctgctctcag tgagaagcgc acgctggagg gcgagctgca 700

 tgatctgcgg ggccaggtgg ccaagcttga ggcagcccta ggtgaggcca 750

 agaagcaact tcaggatgag atgctgcggc gggtggatgc tgagaacagg 800

 ctgcagacca tgaaggagga actggacttc cagaagaaca tctacagtga 850

 ggagctgcgt gagaccaagc gccgtcatga gacccgactg gtggagattg 900

 acaatgggaa gcagcgtgag tttgagagcc ggctggcgga tgcgctgcag 950

 gaactgcggg cccagcatga ggaccaggtg gagcagtata agaaggagct 1000

 ggagaagact tattctgcca agctggacaa tgccaggcag tctgctgaga 1050

 ggaacagcaa cctggtgggg gctgcccacg aggagctgca gcagtcgcgc 1100

 atccgcatcg acagcctctc tgcccagctc agccagctcc agaagcagct 1150

 ggcagccaag gaggcgaagc ttcgagacct ggaggactca ctggcccgtg 1200

 agcgggacac cagccggcgg ctgctggcgg aaaaggagcg ggagatggcc 1250

 gagatgcggg caaggatgca gcagcagctg gacgagtacc aggagcttct 1300

 ggacatcaag ctggccctgg acatggagat ccacgcctac cgcaagctct 1350

 tggagggcga ggaggagagg ctacgcctgt cccccagccc tacctcgcag 1400

 cgcagccgtg gccgtgcttc ctctcactca tcccagacac agggtggggg 1450

 cagcgtcacc aaaaagcgca aactggagtc cactgagagc cgcagcagct 1500

 tctcacagca cgcacgcact agcgggcgcg tggccgtgga ggaggtggat 1550

 gaggagggca agtttgtccg gctgcgcaac aagtccaatg aggaccagtc 1600

 catgggcaat tggcagatca agcgccagaa tggagatgat cccttgctga 1650

 cttaccggtt cccaccaaag ttcaccctga aggctgggca ggtggtgacg 1700

 atctgggctg caggagctgg ggccacccac agccccccta ccgacctggt 1750

 gtggaaggca cagaacacct ggggctgcgg gaacagcctg cgtacggctc 1800

 tcatcaactc cactggggaa gaagtggcca tgcgcaagct ggtgcgctca 1850

 gtgactgtgg ttgaggacga cgaggatgag gatggagatg acctgctcca 1900

 tcaccaccac ggctcccact gcagcagctc gggggacccc gctgagtaca 1950

 acctgcgctc gcgcaccgtg ctgtgcggga cctgcgggca gcctgccgac 2000

 aaggcatctg ccagcggctc aggagcccag gtgggcggac ccatctcctc 2050

 tggctcttct gcctccagtg tcacggtcac tcgcagctac cgcagtgtgg 2100

 ggggcagtgg gggtggcagc ttcggggaca atctggtcac ccgctcctac 2150

 ctcctgggca actccagccc ccgaacccag agcccccaga actgcagcat 2200

 catgtaatct gggacctgcc aggcaggggt gggggtggag gcttcctgcg 2250

 tcctcctcac ctcatgccca ccccctgccc tgcacgtcat gggagggggc 2300

 ttgaagccaa agaaaaataa ccctttggtt tttttcttct gtattttttt 2350

 ttctaagaga agttattttc tacagtggtt ttatactgaa ggaaaaacac 2400

 aagcaaaaaa aaaaaaaagc atctatctca tctatctcaa tcctaatttc 2450

 tcctcccttc cttttccctg cttccaggaa actccacatc tgccttaaaa 2500

 ccaaagaggg cttcctctag aagccaaggg aaaggggtgc ttttatagag 2550

 gctagcttct gcttttctgc cctggctgct gcccccaccc cggggaccct 2600

 gtgacatggt gcctgagagg caggcataga ggcttctccg ccagcctcct 2650

 ctggacggca ggctcactgc caggccagcc tccgagaggg agagagagag 2700

 agagaggaca gcttgagccg ggcccctggg cttggcctgc tgtgattcca 2750

 ctacacctgg ctgaggttcc tctgcctgcc ccgcccccag tccccacccc 2800

 tgcccccagc cccggggtga gtccattctc ccaggtacca gctgcgcttg 2850

 cttttctgta ttttatttag acaagagatg ggaatgaggt gggaggtgga 2900

 agaagggaga agaaaggtga gtttgagctg ccttccctag ctttagaccc 2950

 tgggtgggct ctgtgcagtc actggaggtt gaagccaagt ggggtgctgg 3000

 gaggagggag agggaggtca ctggaaaggg gagagcctgc tggcacccac 3050

 cgtggaggag gaaggcaaga gggggtggag gggtgtggca gtggttttgg 3100

 caaacgctaa agagcccttg cctccccatt tcccatctgc accccttctc 3150

 tcctccccaa atcaatacac tagttgtttc t 3181

<210> 882
<211> 664
<212> PRT
<213> Homo sapien

<400> 882
 Met Glu Thr Pro Ser Gln Arg Arg Ala Thr Arg Ser Gly Ala Gln
   1               5                  10                  15

 Ala Ser Ser Thr Pro Leu Ser Pro Thr Arg Ile Thr Arg Leu Gln
                  20                  25                  30

 Glu Lys Glu Asp Leu Gln Glu Leu Asn Asp Arg Leu Ala Val Tyr
                  35                  40                  45

 Ile Asp Arg Val Arg Ser Leu Glu Thr Glu Asn Ala Gly Leu Arg
                  50                  55                  60

 Leu Arg Ile Thr Glu Ser Glu Glu Val Val Ser Arg Glu Val Ser
                  65                  70                  75

 Gly Ile Lys Ala Ala Tyr Glu Ala Glu Leu Gly Asp Ala Arg Lys
                  80                  85                  90

 Thr Leu Asp Ser Val Ala Lys Glu Arg Ala Arg Leu Gln Leu Glu
                  95                 100                 105

 Leu Ser Lys Val Arg Glu Glu Phe Lys Glu Leu Lys Ala Arg Asn
                 110                 115                 120

 Thr Lys Lys Glu Gly Asp Leu Ile Ala Ala Gln Ala Arg Leu Lys
                 125                 130                 135

 Asp Leu Glu Ala Leu Leu Asn Ser Lys Glu Ala Ala Leu Ser Thr
                 140                 145                 150

 Ala Leu Ser Glu Lys Arg Thr Leu Glu Gly Glu Leu His Asp Leu
                 155                 160                 165

 Arg Gly Gln Val Ala Lys Leu Glu Ala Ala Leu Gly Glu Ala Lys
                 170                 175                 180

 Lys Gln Leu Gln Asp Glu Met Leu Arg Arg Val Asp Ala Glu Asn
                 185                 190                 195

 Arg Leu Gln Thr Met Lys Glu Glu Leu Asp Phe Gln Lys Asn Ile
                 200                 205                 210

 Tyr Ser Glu Glu Leu Arg Glu Thr Lys Arg Arg His Glu Thr Arg
                 215                 220                 225

 Leu Val Glu Ile Asp Asn Gly Lys Gln Arg Glu Phe Glu Ser Arg
                 230                 235                 240

 Leu Ala Asp Ala Leu Gln Glu Leu Arg Ala Gln His Glu Asp Gln
                 245                 250                 255

 Val Glu Gln Tyr Lys Lys Glu Leu Glu Lys Thr Tyr Ser Ala Lys
                 260                 265                 270

 Leu Asp Asn Ala Arg Gln Ser Ala Glu Arg Asn Ser Asn Leu Val
                 275                 280                 285

 Gly Ala Ala His Glu Glu Leu Gln Gln Ser Arg Ile Arg Ile Asp
                 290                 295                 300

 Ser Leu Ser Ala Gln Leu Ser Gln Leu Gln Lys Gln Leu Ala Ala
                 305                 310                 315

 Lys Glu Ala Lys Leu Arg Asp Leu Glu Asp Ser Leu Ala Arg Glu
                 320                 325                 330

 Arg Asp Thr Ser Arg Arg Leu Leu Ala Glu Lys Glu Arg Glu Met
                 335                 340                 345

 Ala Glu Met Arg Ala Arg Met Gln Gln Gln Leu Asp Glu Tyr Gln
                 350                 355                 360

 Glu Leu Leu Asp Ile Lys Leu Ala Leu Asp Met Glu Ile His Ala
                 365                 370                 375

 Tyr Arg Lys Leu Leu Glu Gly Glu Glu Glu Arg Leu Arg Leu Ser
                 380                 385                 390

 Pro Ser Pro Thr Ser Gln Arg Ser Arg Gly Arg Ala Ser Ser His
                 395                 400                 405

 Ser Ser Gln Thr Gln Gly Gly Gly Ser Val Thr Lys Lys Arg Lys
                 410                 415                 420

 Leu Glu Ser Thr Glu Ser Arg Ser Ser Phe Ser Gln His Ala Arg
                 425                 430                 435

 Thr Ser Gly Arg Val Ala Val Glu Glu Val Asp Glu Glu Gly Lys
                 440                 445                 450

 Phe Val Arg Leu Arg Asn Lys Ser Asn Glu Asp Gln Ser Met Gly
                 455                 460                 465

 Asn Trp Gln Ile Lys Arg Gln Asn Gly Asp Asp Pro Leu Leu Thr
                 470                 475                 480

 Tyr Arg Phe Pro Pro Lys Phe Thr Leu Lys Ala Gly Gln Val Val
                 485                 490                 495

 Thr Ile Trp Ala Ala Gly Ala Gly Ala Thr His Ser Pro Pro Thr
                 500                 505                 510

 Asp Leu Val Trp Lys Ala Gln Asn Thr Trp Gly Cys Gly Asn Ser
                 515                 520                 525

 Leu Arg Thr Ala Leu Ile Asn Ser Thr Gly Glu Glu Val Ala Met
                 530                 535                 540

 Arg Lys Leu Val Arg Ser Val Thr Val Val Glu Asp Asp Glu Asp
                 545                 550                 555

 Glu Asp Gly Asp Asp Leu Leu His His His His Gly Ser His Cys
                 560                 565                 570

 Ser Ser Ser Gly Asp Pro Ala Glu Tyr Asn Leu Arg Ser Arg Thr
                 575                 580                 585

 Val Leu Cys Gly Thr Cys Gly Gln Pro Ala Asp Lys Ala Ser Ala
                 590                 595                 600

 Ser Gly Ser Gly Ala Gln Val Gly Gly Pro Ile Ser Ser Gly Ser
                 605                 610                 615

 Ser Ala Ser Ser Val Thr Val Thr Arg Ser Tyr Arg Ser Val Gly
                 620                 625                 630

 Gly Ser Gly Gly Gly Ser Phe Gly Asp Asn Leu Val Thr Arg Ser
                 635                 640                 645

 Tyr Leu Leu Gly Asn Ser Ser Pro Arg Thr Gln Ser Pro Gln Asn
                 650                 655                 660

 Cys Ser Ile Met


<210> 883
<211> 3198
<212> DNA
<213> Homo sapien

<400> 883
 ttgggaggag cagtctctcc gctcgtctcc cggagctttc tccattgtct 50

 ctgcctttac aacagaggga gacgatggac tgagctgatc cgcaccatgg 100

 agtctcgggt cttactgaga acattctgtt tgatcttcgg tctcggagca 150

 gtttgggggc ttggtgtgga cccttcccta cagattgacg tcttaacaga 200

 gttagaactt ggggagtcca cgaccggagt gcgtcaggtc ccggggctgc 250

 ataatgggac gaaagccttt ctctttcaag atactcccag aagcataaaa 300

 gcatccactg ctacagctga acagtttttt cagaagctga gaaataaaca 350

 tgaatttact attttggtga ccctaaaaca gacccactta aattcaggag 400

 ttattctctc aattcaccac ttggatcaca ggtacctgga actggaaagt 450

 agtggccatc ggaatgaagt cagactgcat taccgctcag gcagtcaccg 500

 ccctcacaca gaagtgtttc cttacatttt ggctgatgac aagtggcaca 550

 agctctcctt agccatcagt gcttcccatt tgattttaca cattgactgc 600

 aataaaattt atgaaagggt agtagaaaag ccctccacag acttgcctct 650

 aggcacaaca ttttggctag gacagagaaa taatgcgcat ggatatttta 700

 agggtataat gcaagatgtc caattacttg tcatgcccca gggatttatt 750

 gctcagtgcc cagatcttaa tcgcacctgt ccaacttgca atgacttcca 800

 tggacttgtg cagaaaatca tggagctaca ggatatttta gccaaaacat 850

 cagccaagct gtctcgagct gaacagcgaa tgaatagatt ggatcagtgc 900

 tattgtgaaa ggacttgcac catgaaggga accacctacc gagaatttga 950

 gtcctggata gacggctgta agaactgcac atgcctgaat ggaaccatcc 1000

 agtgtgaaac tctaatctgc ccaaatcctg actgcccact taagtcggct 1050

 cttgcgtatg tggatggcaa atgctgtaag gaatgcaaat cgatatgcca 1100

 atttcaagga cgaacctact ttgaaggaga aagaaataca gtctattcct 1150

 cttctggagt atgtgttctc tatgagtgca aggaccagac catgaaactt 1200

 gttgagagtt caggctgtcc agctttggat tgtccagagt ctcatcagat 1250

 aaccttgtct cacagctgtt gcaaagtttg taaaggttat gacttttgtt 1300

 ctgaaaggca taactgcatg gagaattcca tctgcagaaa tctgaatgac 1350

 agggctgttt gtagctgtcg agatggtttt agggctcttc gagaggataa 1400

 tgcctactgt gaagacatcg atgagtgtgc tgaagggcgc cattactgtc 1450

 gtgaaaatac aatgtgtgtc aacaccccgg gttcttttat gtgcatctgc 1500

 aaaactggat acatcagaat tgatgattat tcatgtacag aacatgatga 1550

 gtgtatcaca aatcagcaca actgtgatga aaatgcttta tgcttcaaca 1600

 ctgttggagg acacaactgt gtttgcaagc cgggctatac agggaatgga 1650

 acgacatgca aagcattttg caaagatggc tgtaggaatg gaggagcctg 1700

 tattgccgct aatgtgtgtg cctgcccaca aggcttcact ggacccagct 1750

 gtgaaacgga cattgatgaa tgctctgatg gttttgttca atgtgacagt 1800

 cgtgctaatt gcattaacct gcctggatgg taccactgtg agtgcagaga 1850

 tggctaccat gacaatggga tgttttcacc aagtggagaa tcgtgtgaag 1900

 atattgatga gtgtgggacc gggaggcaca gctgtgccaa tgataccatt 1950

 tgcttcaatt tggatggcgg atatgattgt cgatgtcctc atggaaagaa 2000

 ttgcacaggg gactgcatcc atgatggaaa agttaagcac aatggtcaga 2050

 tttgggtgtt ggaaaatgac aggtgctctg tgtgctcatg tcagaatgga 2100

 ttcgttatgt gtcgacggat ggtctgtgac tgtgagaatc ccacagttga 2150

 tcttttttgc tgccctgaat gtgacccaag gcttagtagt cagtgcctcc 2200

 atcaaaatgg ggaaactttg tataacagtg gtgacacctg ggtccagaat 2250

 tgtcaacagt gccgctgctt gcaaggggaa gttgattgtt ggcccctgcc 2300

 ttgcccagat gtggagtgtg aattcagcat tctcccagag aatgagtgct 2350

 gcccgcgctg tgtcacagac ccttgccagg ctgacaccat ccgcaatgac 2400

 atcaccaaga cttgcctgga cgaaatgaat gtggttcgct tcaccgggtc 2450

 ctcttggatc aaacatggca ctgagtgtac tctctgccag tgcaagaatg 2500

 gccacatctg ttgctcagtg gatccacagt gccttcagga actgtgaagt 2550

 taactgtctc atgggagatt tctgttaaaa gaatgttctt tcattaaaag 2600

 accaaaaaga agttaaaact taaattgggt gatttgtggg cagctaaatg 2650

 cagctttgtt aatagctgag tgaactttca attatgaaat ttgtggagct 2700

 tgacaaaatc acaaaaggaa aattactggg gcaaaattag acctcaagtc 2750

 tgcctctact gtgtctcaca tcaccatgta gaagaatggg cgtacagtat 2800

 ataccgtgac atcctgaacc ctggatagaa agcctgagcc cattggatct 2850

 gtgaaagcct ctagcttcac tggtgcagaa aattttcctc tagatcagaa 2900

 tcttcagaat cagttaggtt cctcactgca agaaataaaa tgtcaggcag 2950

 tgaatgaatt atattttcag aagtaaagca aagaagctat aacatgttat 3000

 gtacagtaca ctctgaaaag aaatctgaaa caagttattg taatgataaa 3050

 aataatgcac aggcatggtt acttaatatt ttctaacagg aaaagtcatc 3100

 cctatttcct tgttttactg cacttaatat tatttggttg aatttgttca 3150

 gtataagctc gttcttgtgc aaaattaaat aaatatttct cttacctt 3198

<210> 884
<211> 816
<212> PRT
<213> Homo sapien

<400> 884
 Met Glu Ser Arg Val Leu Leu Arg Thr Phe Cys Leu Ile Phe Gly
   1               5                  10                  15

 Leu Gly Ala Val Trp Gly Leu Gly Val Asp Pro Ser Leu Gln Ile
                  20                  25                  30

 Asp Val Leu Thr Glu Leu Glu Leu Gly Glu Ser Thr Thr Gly Val
                  35                  40                  45

 Arg Gln Val Pro Gly Leu His Asn Gly Thr Lys Ala Phe Leu Phe
                  50                  55                  60

 Gln Asp Thr Pro Arg Ser Ile Lys Ala Ser Thr Ala Thr Ala Glu
                  65                  70                  75

 Gln Phe Phe Gln Lys Leu Arg Asn Lys His Glu Phe Thr Ile Leu
                  80                  85                  90

 Val Thr Leu Lys Gln Thr His Leu Asn Ser Gly Val Ile Leu Ser
                  95                 100                 105

 Ile His His Leu Asp His Arg Tyr Leu Glu Leu Glu Ser Ser Gly
                 110                 115                 120

 His Arg Asn Glu Val Arg Leu His Tyr Arg Ser Gly Ser His Arg
                 125                 130                 135

 Pro His Thr Glu Val Phe Pro Tyr Ile Leu Ala Asp Asp Lys Trp
                 140                 145                 150

 His Lys Leu Ser Leu Ala Ile Ser Ala Ser His Leu Ile Leu His
                 155                 160                 165

 Ile Asp Cys Asn Lys Ile Tyr Glu Arg Val Val Glu Lys Pro Ser
                 170                 175                 180

 Thr Asp Leu Pro Leu Gly Thr Thr Phe Trp Leu Gly Gln Arg Asn
                 185                 190                 195

 Asn Ala His Gly Tyr Phe Lys Gly Ile Met Gln Asp Val Gln Leu
                 200                 205                 210

 Leu Val Met Pro Gln Gly Phe Ile Ala Gln Cys Pro Asp Leu Asn
                 215                 220                 225

 Arg Thr Cys Pro Thr Cys Asn Asp Phe His Gly Leu Val Gln Lys
                 230                 235                 240

 Ile Met Glu Leu Gln Asp Ile Leu Ala Lys Thr Ser Ala Lys Leu
                 245                 250                 255

 Ser Arg Ala Glu Gln Arg Met Asn Arg Leu Asp Gln Cys Tyr Cys
                 260                 265                 270

 Glu Arg Thr Cys Thr Met Lys Gly Thr Thr Tyr Arg Glu Phe Glu
                 275                 280                 285

 Ser Trp Ile Asp Gly Cys Lys Asn Cys Thr Cys Leu Asn Gly Thr
                 290                 295                 300

 Ile Gln Cys Glu Thr Leu Ile Cys Pro Asn Pro Asp Cys Pro Leu
                 305                 310                 315

 Lys Ser Ala Leu Ala Tyr Val Asp Gly Lys Cys Cys Lys Glu Cys
                 320                 325                 330

 Lys Ser Ile Cys Gln Phe Gln Gly Arg Thr Tyr Phe Glu Gly Glu
                 335                 340                 345

 Arg Asn Thr Val Tyr Ser Ser Ser Gly Val Cys Val Leu Tyr Glu
                 350                 355                 360

 Cys Lys Asp Gln Thr Met Lys Leu Val Glu Ser Ser Gly Cys Pro
                 365                 370                 375

 Ala Leu Asp Cys Pro Glu Ser His Gln Ile Thr Leu Ser His Ser
                 380                 385                 390

 Cys Cys Lys Val Cys Lys Gly Tyr Asp Phe Cys Ser Glu Arg His
                 395                 400                 405

 Asn Cys Met Glu Asn Ser Ile Cys Arg Asn Leu Asn Asp Arg Ala
                 410                 415                 420

 Val Cys Ser Cys Arg Asp Gly Phe Arg Ala Leu Arg Glu Asp Asn
                 425                 430                 435

 Ala Tyr Cys Glu Asp Ile Asp Glu Cys Ala Glu Gly Arg His Tyr
                 440                 445                 450

 Cys Arg Glu Asn Thr Met Cys Val Asn Thr Pro Gly Ser Phe Met
                 455                 460                 465

 Cys Ile Cys Lys Thr Gly Tyr Ile Arg Ile Asp Asp Tyr Ser Cys
                 470                 475                 480

 Thr Glu His Asp Glu Cys Ile Thr Asn Gln His Asn Cys Asp Glu
                 485                 490                 495

 Asn Ala Leu Cys Phe Asn Thr Val Gly Gly His Asn Cys Val Cys
                 500                 505                 510

 Lys Pro Gly Tyr Thr Gly Asn Gly Thr Thr Cys Lys Ala Phe Cys
                 515                 520                 525

 Lys Asp Gly Cys Arg Asn Gly Gly Ala Cys Ile Ala Ala Asn Val
                 530                 535                 540

 Cys Ala Cys Pro Gln Gly Phe Thr Gly Pro Ser Cys Glu Thr Asp
                 545                 550                 555

 Ile Asp Glu Cys Ser Asp Gly Phe Val Gln Cys Asp Ser Arg Ala
                 560                 565                 570

 Asn Cys Ile Asn Leu Pro Gly Trp Tyr His Cys Glu Cys Arg Asp
                 575                 580                 585

 Gly Tyr His Asp Asn Gly Met Phe Ser Pro Ser Gly Glu Ser Cys
                 590                 595                 600

 Glu Asp Ile Asp Glu Cys Gly Thr Gly Arg His Ser Cys Ala Asn
                 605                 610                 615

 Asp Thr Ile Cys Phe Asn Leu Asp Gly Gly Tyr Asp Cys Arg Cys
                 620                 625                 630

 Pro His Gly Lys Asn Cys Thr Gly Asp Cys Ile His Asp Gly Lys
                 635                 640                 645

 Val Lys His Asn Gly Gln Ile Trp Val Leu Glu Asn Asp Arg Cys
                 650                 655                 660

 Ser Val Cys Ser Cys Gln Asn Gly Phe Val Met Cys Arg Arg Met
                 665                 670                 675

 Val Cys Asp Cys Glu Asn Pro Thr Val Asp Leu Phe Cys Cys Pro
                 680                 685                 690

 Glu Cys Asp Pro Arg Leu Ser Ser Gln Cys Leu His Gln Asn Gly
                 695                 700                 705

 Glu Thr Leu Tyr Asn Ser Gly Asp Thr Trp Val Gln Asn Cys Gln
                 710                 715                 720

 Gln Cys Arg Cys Leu Gln Gly Glu Val Asp Cys Trp Pro Leu Pro
                 725                 730                 735

 Cys Pro Asp Val Glu Cys Glu Phe Ser Ile Leu Pro Glu Asn Glu
                 740                 745                 750

 Cys Cys Pro Arg Cys Val Thr Asp Pro Cys Gln Ala Asp Thr Ile
                 755                 760                 765

 Arg Asn Asp Ile Thr Lys Thr Cys Leu Asp Glu Met Asn Val Val
                 770                 775                 780

 Arg Phe Thr Gly Ser Ser Trp Ile Lys His Gly Thr Glu Cys Thr
                 785                 790                 795

 Leu Cys Gln Cys Lys Asn Gly His Ile Cys Cys Ser Val Asp Pro
                 800                 805                 810

 Gln Cys Leu Gln Glu Leu
                 815

<210> 885
<211> 4695
<212> DNA
<213> Homo sapien

<400> 885
 gggggaggga aacggagcag taacaagtat cccagagggt gctgctgagg 50

 cgacgatggc cgaggggccc gaggaagccc gaggccaccc tcccgggcag 100

 gacgatggcg ggggggacca cgagcccgtc ccttccctga gaggccctcc 150

 taccaccgcc gtcccatgcc cccgcgacga cccccaggcc gaaccccagg 200

 ccccgggccg gcccacagcc ccgggcctcg cggctgccgc cgcagccgac 250

 aaattggagc cgccgcgcga gctcaggaag cgcggggagg cggcctccgg 300

 ctccggtgca gagctgcagg agcaggcggg ctgcgaggcg cccgaagccg 350

 cggcgccacg agagagacca gctcggctga gcgcccgcga gtactcccgg 400

 caagtgcacg agtggctgtg gcagtcctac tgcggctacc tcacctggca 450

 cagcggcctg gccgccttcc cagcctactg cagcccccag ccctccccgc 500

 aaagcttccc ttcgggcggc gctgcagtcc cccaggccgc ggcgccgccg 550

 cccccgcagc tgggctatta caaccccttc tacttcctga gccccggggc 600

 cgcggggcct gacccgcgga cagctgccgg catcagcacc cctgctccag 650

 tcgcgggcct gggaccccgg gctcctcacg tgcaggcgtc ggtccgggcc 700

 actccagtga cgagggtagg atccgcagcc ccttcgcgaa gcccgagcga 750

 gaccgggcga caggcaggca gagaatatgt tattccatcc ttggcccaca 800

 gatttatggc agagatggtg gatttcttta ttctcttctt tataaaagca 850

 accattgtct taagcattat gcacctcagt gggataaagg atatctctaa 900

 gtttgctatg cattatataa tagaagaaat agatgaagac acatcaatgg 950

 aagacttgca gaaaatgatg gttgtggcac ttatatacag attattagtt 1000

 tgtttctatg agataatttg catttgggga gcaggtggag ctaccccagg 1050

 gaagttcctg ctggggcttc gagttgtgac atgtgataca tcagtgctta 1100

 ttgcaccaag tcgggtttta gtgattcctt cctcaaatgt tagcattaca 1150

 acgtccacta tccgagcttt gatcaagaat ttttcaattg cttctttttt 1200

 ccctgctttc atcacactgc tgttttttca gcataatcga acagcttatg 1250

 acattgtagc aggaaccatt gtggtaaaaa gaaatggggt cagatgatgc 1300

 cccccaaaac cctgatttcc acacactaag actaaattat gtatcaaggc 1350

 catcagtatc cctgggttac actaattgat gatttagaaa ttaaagcagt 1400

 cactccagtg tgatgcaggt gactactctg aaagtattga ttatacttga 1450

 atgccaaaga acttgtccag aagaaaaacc tgttaaattc aagtattaaa 1500

 atttttagat caaaaaggca aatgatttta taaacaatgg acaatatata 1550

 ctttcttaag atctaaggta ctttcttaag atctaagaat ttgctgaaag 1600

 cattttcagc tttgaaatct ccaaatgaaa ctttaaaatt tattttggtt 1650

 tatcccaaaa taatggaaaa tgtccagttg tgttttgtaa acacctatgt 1700

 aactcatctt ttagtttaca cttcctgggg aaattgtctt tggtgtttag 1750

 aggagggaat gagaacacaa attggataat ccactgtctc ccatcccagg 1800

 aggtggtgag ttggctacaa gagaaaggga caagtgaggc aggcctagca 1850

 gttcccttac ctgaagtttt caaatccata ctgcagttcc ctctcgtaat 1900

 gatgtaactt tacaactatt cttaatgctt gaacatgtat ttaggggcaa 1950

 gtttctcatg atgatgaaaa agtatcaagt catattgcta tgttaattgg 2000

 tttttttttt taaaaggtaa gttagtgatt actgttaatg gtgggggagt 2050

 aagttttcac tgtaaattga acttataatt tatgtgcaag tgttttcagt 2100

 gccctgaatc aaactataaa tgtggggaga aatcacctcc atcaaacagt 2150

 tgcatattta ctgtaaaagt attcccagta tgtgtgcagc atgaagaaag 2200

 tattagtgct tctcagtgtt ctcagtgtaa attctattta tatacagcat 2250

 attcacatac tactttcctt atattttata tagttctatg actgttgaaa 2300

 catcaaggag ttaaaaaaat cttaatattt catgattaac tctaagtact 2350

 attaatagct tgcgaaatat tagcaatttt cccattatgg actatctctc 2400

 taaagcaaga gagactagca ttcccagaca tcattctagg gtctttaagc 2450

 tcattttggg tctgctaaag tttgggggga aatgttacgc aaagtgatac 2500

 tgtgtatgtt gccattttgc tttattcttc tgttgaagca aaattgtggg 2550

 gttttattat gtgtgtgtgc ttttcctaga tgtcccagtt agctgtgctg 2600

 agatatacct gtactattta tggtttaagt tttgattctt aggtattttc 2650

 tccagctctg acattgtttt ccaaagacac actaaactgc attgcacagt 2700

 tcaaaatttg attacttaag ggatcaatct aggtggtgtt cttggtctta 2750

 aatttaacag caaacacagc acatatctat tatcactata ttaattttca 2800

 aaggtttttc tgtgacgttt aaaactgtga caacagatat tcacatttga 2850

 ttatagaaac ttaatgtcta ttaataattt tagtacaaaa tttcataaac 2900

 cgtgtttttc aaaataagtt tatgtcaaat ccagcttccc agaaacacta 2950

 ataattaagt acatcaatgt actaaataaa tcattcagtt gcacccatgg 3000

 ggaagattgt gttactgccc ttcacagtga aaaaaagaaa aatctttcat 3050

 ttttaaaatt aggagatgtt acgtaacttg gcactttagt agtgtataca 3100

 ctagcattag tttatacacc acttttgccg ctggggattc aagttgaaat 3150

 gtccctcaat catataggtc tggaatacat ctttcattca taatttctgc 3200

 tcagataatt gaatagtttg ccatcgagat tattttcatt tatactataa 3250

 aacaaaagca aactagtcca gtttaatttt ttgtacttag aatattgcac 3300

 attttctata tatgagttat tcagattagt atctatgtag gttcagtcag 3350

 atccaaccat ggattcgagg tattatactg tataacccta caaaatacat 3400

 agaagtatta tttgccttca taatagaacc caagagtctg tttcaattta 3450

 tgaattcagt atttgcaccg agattttgat tcccaaagtt tggaaaaaaa 3500

 tgacaaaaca acgagggaag aaggaaccag accttagtgc cacatatttt 3550

 tctcttgggg ttgtaaggta gtctcctgct ttccagaaca ctttattata 3600

 tttcacttat agacctgatt ttctgtgtca aagtataatt ctcatgctga 3650

 agctgtagcc taaaaagcca aaagaaagtt gtcttcattg tacaaacata 3700

 ttcatcactt taacaataag ggaacaaaat ttagtattca agctgagtga 3750

 gaatactggt tcaatggaca tgtccctaag ataaaccaga attggcagtt 3800

 aatttaggcg tctagaaaat ctcagttccc accagtaaaa ttatcctgag 3850

 tagctaatgc accttgagaa aaatctggca tactgaataa gtaacattaa 3900

 cttgggagcc aagagctggg taagccttac ctttagacta ctctgtgact 3950

 acagaaataa agccagcact tttggaacta ataagccttc acttgtcagt 4000

 atcataaaga gtattgccca actgaacttt gctcccactg gtttaatagt 4050

 tacttatttc tgcctaagca ctcaccttcc gattttaccc aagtatatat 4100

 ataggataga aaaaaatgca ttatatttga gagctcactt cgcccgaatt 4150

 acaaaatgag tgtttttaga ttcaagtgac ggtaaaagga tttgttccct 4200

 tcagtgactt gagtgtttta gttatgcata agtatttcta gcaaaggaag 4250

 ggtagaaagg aattgaaaat taatttacac tagttgctac ttgggaataa 4300

 agggcttttt gaggggggta tggatattaa atgttttcgt tatatactta 4350

 tccctattaa aacaggcagt tgtttctttg aatatgccta aataacagta 4400

 ttcttaaaat ctgacagaca agtaacatgt caattacttg atattccttg 4450

 tctccagtac cacaggccac tcttgacatc ccatgtttgc ctggataaag 4500

 ttcctcattt caaacagtat acatacttct ttgcagttca ttatagtaag 4550

 gcttaacctg taaacagtat ctgatggccc acctataaat aaaattcagc 4600

 attctatttt taataatttg tatgccacca atttgtatta tttgtctcaa 4650

 taaatactta gtcatcgatg caaaaaaaaa aaaaaaaaaa aaaaa 4695

<210> 886
<211> 413
<212> PRT
<213> Homo sapien

<400> 886
 Met Ala Glu Gly Pro Glu Glu Ala Arg Gly His Pro Pro Gly Gln
   1               5                  10                  15

 Asp Asp Gly Gly Gly Asp His Glu Pro Val Pro Ser Leu Arg Gly
                  20                  25                  30

 Pro Pro Thr Thr Ala Val Pro Cys Pro Arg Asp Asp Pro Gln Ala
                  35                  40                  45

 Glu Pro Gln Ala Pro Gly Arg Pro Thr Ala Pro Gly Leu Ala Ala
                  50                  55                  60

 Ala Ala Ala Ala Asp Lys Leu Glu Pro Pro Arg Glu Leu Arg Lys
                  65                  70                  75

 Arg Gly Glu Ala Ala Ser Gly Ser Gly Ala Glu Leu Gln Glu Gln
                  80                  85                  90

 Ala Gly Cys Glu Ala Pro Glu Ala Ala Ala Pro Arg Glu Arg Pro
                  95                 100                 105

 Ala Arg Leu Ser Ala Arg Glu Tyr Ser Arg Gln Val His Glu Trp
                 110                 115                 120

 Leu Trp Gln Ser Tyr Cys Gly Tyr Leu Thr Trp His Ser Gly Leu
                 125                 130                 135

 Ala Ala Phe Pro Ala Tyr Cys Ser Pro Gln Pro Ser Pro Gln Ser
                 140                 145                 150

 Phe Pro Ser Gly Gly Ala Ala Val Pro Gln Ala Ala Ala Pro Pro
                 155                 160                 165

 Pro Pro Gln Leu Gly Tyr Tyr Asn Pro Phe Tyr Phe Leu Ser Pro
                 170                 175                 180

 Gly Ala Ala Gly Pro Asp Pro Arg Thr Ala Ala Gly Ile Ser Thr
                 185                 190                 195

 Pro Ala Pro Val Ala Gly Leu Gly Pro Arg Ala Pro His Val Gln
                 200                 205                 210

 Ala Ser Val Arg Ala Thr Pro Val Thr Arg Val Gly Ser Ala Ala
                 215                 220                 225

 Pro Ser Arg Ser Pro Ser Glu Thr Gly Arg Gln Ala Gly Arg Glu
                 230                 235                 240

 Tyr Val Ile Pro Ser Leu Ala His Arg Phe Met Ala Glu Met Val
                 245                 250                 255

 Asp Phe Phe Ile Leu Phe Phe Ile Lys Ala Thr Ile Val Leu Ser
                 260                 265                 270

 Ile Met His Leu Ser Gly Ile Lys Asp Ile Ser Lys Phe Ala Met
                 275                 280                 285

 His Tyr Ile Ile Glu Glu Ile Asp Glu Asp Thr Ser Met Glu Asp
                 290                 295                 300

 Leu Gln Lys Met Met Val Val Ala Leu Ile Tyr Arg Leu Leu Val
                 305                 310                 315

 Cys Phe Tyr Glu Ile Ile Cys Ile Trp Gly Ala Gly Gly Ala Thr
                 320                 325                 330

 Pro Gly Lys Phe Leu Leu Gly Leu Arg Val Val Thr Cys Asp Thr
                 335                 340                 345

 Ser Val Leu Ile Ala Pro Ser Arg Val Leu Val Ile Pro Ser Ser
                 350                 355                 360

 Asn Val Ser Ile Thr Thr Ser Thr Ile Arg Ala Leu Ile Lys Asn
                 365                 370                 375

 Phe Ser Ile Ala Ser Phe Phe Pro Ala Phe Ile Thr Leu Leu Phe
                 380                 385                 390

 Phe Gln His Asn Arg Thr Ala Tyr Asp Ile Val Ala Gly Thr Ile
                 395                 400                 405

 Val Val Lys Arg Asn Gly Val Arg
                 410

<210> 887
<211> 1060
<212> DNA
<213> Homo sapien

<400> 887
 cgcgggccga ctggtgttta tccgtcactc gccgaggttc cttgggtcat 50

 ggtgccagcc tgactgagaa gaggacgctc ccgggagacg aatgaggaac 100

 cacctcctcc tactgttcaa gtacaggggc ctggtccgca aagggaagaa 150

 aagcaaaaga cgaaaatggc taaattcgtg atccgcccag ccactgccgc 200

 cgactgcagt gacatactgc ggctgatcaa ggagctggct aaatatgaat 250

 acatggaaga acaagtaatc ttaactgaaa aagatctgct agaagatggt 300

 tttggagagc acccctttta ccactgcctg gttgcagaag tgccgaaaga 350

 gcactggact ccggaaggac acagcattgt tggttttgcc atgtactatt 400

 ttacctatga cccgtggatt ggcaagttat tgtatcttga ggacttcttc 450

 gtgatgagtg attatagagg ctttggcata ggatcagaaa ttctgaagaa 500

 tctaagccag gttgcaatga ggtgtcgctg cagcagcatg cacttcttgg 550

 tagcagaatg gaatgaacca tccatcaact tctataaaag aagaggtgct 600

 tctgatctgt ccagtgaaga gggttggaga ctgttcaaga tcgacaagga 650

 gtacttgcta aaaatggcaa cagaggagtg aggagtgctg ctgtagatga 700

 caacctccat tctattttag aataaattcc caacttctct tgctttctat 750

 gctgtttgta gtgaaataat agaatgagca cccattccaa agctttatta 800

 ccagtggcgt tgttgcatgt ttgaaatgag gtctgtttaa agtggcaatc 850

 tcagatgcag tttggagagt cagatctttc tccttgaata tctttcgata 900

 aacaacaagg tggtgtgatc ttaatatatt tgaaaaaaac ttcattctcg 950

 tgagtcattt aaatgtgtac aatgtacaca ctggtactta gagtttctgt 1000

 ttgattcttt tttaataaac tactctttga tttaaaaaaa aaaaaaaaaa 1050

 aaaaaaaaaa 1060

<210> 888
<211> 171
<212> PRT
<213> Homo sapien

<400> 888
 Met Ala Lys Phe Val Ile Arg Pro Ala Thr Ala Ala Asp Cys Ser
   1               5                  10                  15

 Asp Ile Leu Arg Leu Ile Lys Glu Leu Ala Lys Tyr Glu Tyr Met
                  20                  25                  30

 Glu Glu Gln Val Ile Leu Thr Glu Lys Asp Leu Leu Glu Asp Gly
                  35                  40                  45

 Phe Gly Glu His Pro Phe Tyr His Cys Leu Val Ala Glu Val Pro
                  50                  55                  60

 Lys Glu His Trp Thr Pro Glu Gly His Ser Ile Val Gly Phe Ala
                  65                  70                  75

 Met Tyr Tyr Phe Thr Tyr Asp Pro Trp Ile Gly Lys Leu Leu Tyr
                  80                  85                  90

 Leu Glu Asp Phe Phe Val Met Ser Asp Tyr Arg Gly Phe Gly Ile
                  95                 100                 105

 Gly Ser Glu Ile Leu Lys Asn Leu Ser Gln Val Ala Met Arg Cys
                 110                 115                 120

 Arg Cys Ser Ser Met His Phe Leu Val Ala Glu Trp Asn Glu Pro
                 125                 130                 135

 Ser Ile Asn Phe Tyr Lys Arg Arg Gly Ala Ser Asp Leu Ser Ser
                 140                 145                 150

 Glu Glu Gly Trp Arg Leu Phe Lys Ile Asp Lys Glu Tyr Leu Leu
                 155                 160                 165

 Lys Met Ala Thr Glu Glu
                 170

<210> 889
<211> 2745
<212> DNA
<213> Homo sapien

<400> 889
 ggcccagctg ctgagaggag ttgcctgaga gtgacctttg catctgcctg 50

 tccagccagc atggaaccaa agcggatcag agagggctac cttgtgaaga 100

 aggggagcgt gttcaatacg tggaaaccca tgtgggttgt attgttagaa 150

 gatggaattg aattctataa gaagaaaagt gacaacagcc ccaaaggaat 200

 gatcccgctg aaagggagca ctctgactag cccttgtcaa gactttggca 250

 aaaggatgtt tgtgtttaag atcactacga ccaaacagca ggaccacttc 300

 ttccaggcag ccttcctgga ggagagagat gcctgggttc gggatatcaa 350

 taaggccatt aaatgcattg aaggaggcca gaaatttgcc aggaaatcta 400

 ccaggaggtc cattcgactg ccagaaacca ttgacttagg tgccttatat 450

 ttgtccatga aagacactga aaaaggaata aaagaactga atctagagaa 500

 ggacaagaag atttttaatc actgcttcac aggtaactgc gtcattgatt 550

 ggctggtatc caaccagtct gttaggaatc gccaggaagg cctcatgatt 600

 gcttcatcgc tgctcaatga ggggtatctg cagcctgctg gagacatgtc 650

 caagagtgca gtggatggaa ctgctgaaaa ccctttcctg gacaaccctg 700

 atgccttcta ctactttcca gacagtgggt tcttctgtga agagaattcc 750

 agtgatgatg atgtgattct gaaagaagaa ttcagagggg tcattatcaa 800

 gcagggatgt ttactgaagc aggggcatag aaggaaaaac tggaaagtga 850

 ggaagttcat cttgagagaa gaccctgcct acctgcacta ctatgaccct 900

 gctggggcag aagatcccct gggagcaatt cacttgagag gctgtgtggt 950

 gacttcagtg gagagcaact caaatggcag gaagagtgag gaagagaacc 1000

 tttttgagat catcacagca gatgaagtgc actatttctt gcaagcagcc 1050

 acccccaagg agcgcacaga gtggatcaaa gccatccaga tggcctcccg 1100

 aactgggaag taaagagact cctgcattcc tcctcccctc ctgagggaag 1150

 cccatggaca agctcagtcc aggacctgtc cacttctgtg acaaatcaac 1200

 gggaaacagc ccaggggtgg gaagttttca tttgcagggg ggtctgaatg 1250

 taactcacca tgtggtgtgc aaggttcccc tgcattgtat tgctcactgc 1300

 agcccctctg cccctatcca tgacccccaa gcagatataa caagctgtgc 1350

 agcctcagta ggctgcttgc cctctccagc ctcagggcct cttctggaaa 1400

 atgaagaaat tcaactagta gattcctgag gtccccctag cttaaaaaaa 1450

 aaaaaatctg ccccatgatt ctaacactcg cagtagtgat agtgtatcta 1500

 gttgttctgc tggtgtcctt ccttggctaa gtcttggcct tcagttatct 1550

 tcaaatgtac cagaacctga gccaacgcct ccctgtgaaa ctgttgctga 1600

 tctgtagtac agtaccagga agaaacctct tttgttctct ttagacatct 1650

 tctacttgct cttggccttg agatcgtgta acaaaatgaa ggagggctct 1700

 cttctttctt cctcatccta ctcaaaaact tcccgagagc agtggtggtt 1750

 ttgagggttt tgacttctat tacttttggc agcctggaaa gttgtgtctt 1800

 ctgggaaaga gacccgggga ggccaggagt agctgagggt cctttctgtg 1850

 cccttaaacc gcccagagga gccctattcc actctggttt taggctgatc 1900

 tgagagggtc tccctttgtt cctttctgga gcatttctct aacgtttatt 1950

 acaattagga gggggacccc acatctgtga gattctgttt catttgaggt 2000

 ttacagaaaa aaaaaagtgg ccagatgtgt tccccccatg ggtgagaggc 2050

 ctgggcaact gcctggtgaa tgtgtcttgc ggcagctgca gcaagtggag 2100

 gggctgaact actggccagc tcactggatg atgggttaat acaacaactg 2150

 cactgtaagg actcagagcc acacagaact tctgagaggg gctgttagca 2200

 ttgcgcagca tcttcagttc tccagtaaat gatattgcgt tcgtgcctca 2250

 gctttaagca caagtagcag cagctcctgc ttgagttctg agggcatcat 2300

 ggccctatga ttaaccagag tgatctaacc tagactaaaa ttgggaactt 2350

 atttgcaatt tttgaccctg accactaact agtgattctt ctccaaaatt 2400

 gagaaagaca gcacccattg aaacagatat gtgtgtgaaa gtatattttt 2450

 caattccaga tttttaattt taaggctcca ggaaagaaag gagagtagaa 2500

 catttttcct cattttatca aatcctctct tgccctccct caattcccct 2550

 gtaacattcc tgaagctgtt cccactccca gatggtttta tcaatagcct 2600

 agaggtaaag aactgtcttt ttctctgatt ctttaataaa ttatctttat 2650

 agaatatgca caagtttttc tacactcagt gttaaagtat ttattaatgg 2700

 gaagtcaact taatgttttg aaataaatat atgactctgt ttaat 2745

<210> 890
<211> 350
<212> PRT
<213> Homo sapien

<400> 890
 Met Glu Pro Lys Arg Ile Arg Glu Gly Tyr Leu Val Lys Lys Gly
   1               5                  10                  15

 Ser Val Phe Asn Thr Trp Lys Pro Met Trp Val Val Leu Leu Glu
                  20                  25                  30

 Asp Gly Ile Glu Phe Tyr Lys Lys Lys Ser Asp Asn Ser Pro Lys
                  35                  40                  45

 Gly Met Ile Pro Leu Lys Gly Ser Thr Leu Thr Ser Pro Cys Gln
                  50                  55                  60

 Asp Phe Gly Lys Arg Met Phe Val Phe Lys Ile Thr Thr Thr Lys
                  65                  70                  75

 Gln Gln Asp His Phe Phe Gln Ala Ala Phe Leu Glu Glu Arg Asp
                  80                  85                  90

 Ala Trp Val Arg Asp Ile Asn Lys Ala Ile Lys Cys Ile Glu Gly
                  95                 100                 105

 Gly Gln Lys Phe Ala Arg Lys Ser Thr Arg Arg Ser Ile Arg Leu
                 110                 115                 120

 Pro Glu Thr Ile Asp Leu Gly Ala Leu Tyr Leu Ser Met Lys Asp
                 125                 130                 135

 Thr Glu Lys Gly Ile Lys Glu Leu Asn Leu Glu Lys Asp Lys Lys
                 140                 145                 150

 Ile Phe Asn His Cys Phe Thr Gly Asn Cys Val Ile Asp Trp Leu
                 155                 160                 165

 Val Ser Asn Gln Ser Val Arg Asn Arg Gln Glu Gly Leu Met Ile
                 170                 175                 180

 Ala Ser Ser Leu Leu Asn Glu Gly Tyr Leu Gln Pro Ala Gly Asp
                 185                 190                 195

 Met Ser Lys Ser Ala Val Asp Gly Thr Ala Glu Asn Pro Phe Leu
                 200                 205                 210

 Asp Asn Pro Asp Ala Phe Tyr Tyr Phe Pro Asp Ser Gly Phe Phe
                 215                 220                 225

 Cys Glu Glu Asn Ser Ser Asp Asp Asp Val Ile Leu Lys Glu Glu
                 230                 235                 240

 Phe Arg Gly Val Ile Ile Lys Gln Gly Cys Leu Leu Lys Gln Gly
                 245                 250                 255

 His Arg Arg Lys Asn Trp Lys Val Arg Lys Phe Ile Leu Arg Glu
                 260                 265                 270

 Asp Pro Ala Tyr Leu His Tyr Tyr Asp Pro Ala Gly Ala Glu Asp
                 275                 280                 285

 Pro Leu Gly Ala Ile His Leu Arg Gly Cys Val Val Thr Ser Val
                 290                 295                 300

 Glu Ser Asn Ser Asn Gly Arg Lys Ser Glu Glu Glu Asn Leu Phe
                 305                 310                 315

 Glu Ile Ile Thr Ala Asp Glu Val His Tyr Phe Leu Gln Ala Ala
                 320                 325                 330

 Thr Pro Lys Glu Arg Thr Glu Trp Ile Lys Ala Ile Gln Met Ala
                 335                 340                 345

 Ser Arg Thr Gly Lys
                 350

<210> 891
<211> 3184
<212> DNA
<213> Homo sapien

<400> 891
 ctctgctgtg ctgcctcaaa cgcggagggc tgcgtgcagt gggagcgggc 50

 tccaggagcc cgagcctcca gccgtcctca gagcaaggca gcaccgaggc 100

 ctggccacag caatatccat ctggaagctc ttcccttcac tcccaactct 150

 gaggttgcct aactctttat taaaaattca gaagggggaa tgccagcccc 200

 tagcatggac tgtgatgttt ccactctggt tgcctgtgtg gtggatgtcg 250

 aggtctttac caatcaggag gttaaggaaa aatttggggg actgtttcgg 300

 acttatgatg actgtgtgac gttccagcta tttaagagtt tcagacgtgt 350

 ccgtataaac ttcagcaatc ctaaatctgc agcccgagct aggatagagc 400

 ttcatgaaac ccaattcaga gggaaaaaat taaagctcta ctttgcacag 450

 gttcagactc cagagacaga tggagacaaa ctgcacttgg ctccacccca 500

 gcctgccaaa cagtttctca tctcgccccc ttcctcccca cctgttagct 550

 ggcagcccat caacgatgcc acgccagtcc tcaactatga cctcctctat 600

 gctgtggcca aactaggacc aggagagaag tatgagctcc atgcagggac 650

 tgagtccacc ccaagtgtcg tcgtgcacgt gtgcgacagt gacatagagg 700

 aagaagagga cccaaagact tccccaaagc caaaaatcat ccaaactcgg 750

 cgtcctggcc tgccaccctc cgtgtccaac tgagctgcct gctccttctc 800

 gataatagcc gtctcctctt tatcatgctt tttccccctg ttgtttgtca 850

 aaaaaaattg cctttaaatt cctgggtgtt tggttgtttg agattccttc 900

 cttgttatca agcctctcgg acaaaagggc taggaaaagg tgatatgtct 950

 cctgatcata tcatacccat taagtataac ccattattta gaaggttcta 1000

 gggaaaaaag tagtattttc ttattaaaca atcagcacag cctatatctt 1050

 tgttctctca tgttgatcca agccagagac atcggtaaca aatagcacct 1100

 gtgttgtttg tgaggtgttt cagtcccagt cctgatgtgt gtgcgttgtt 1150

 ctctcctggc cacttaaata ggaccatatg taaacttgac tttgactgca 1200

 tgagatatcc ctatctggtc tcactcagtc ctctgcatcc caacattccc 1250

 aggacatgca tgatcaccag catttatttt cattatttga ggatatctta 1300

 taactcacag attgtcagca tccagccatg tcctatctag attaggaaaa 1350

 tgatcagaat attccagctc aacaagtctg ggtatactca ctattgtgag 1400

 tcaatacacc atagctctgt tgaaattcct ggaggcaaaa ttgaccttgg 1450

 ccccaaagat attcctcaat agatttcaaa caccactccc ctgtagaact 1500

 ctcccagcct cgttggggag gcttgtccag ggtgatagag actgatttca 1550

 gacaaaccta tttattacaa aagtttcatg gtgtctgaat gattgttttc 1600

 tctctttgta tatttgtaca aatgtttcag ctgtgctttt aaaaaatctg 1650

 gatgtttttt atttagtgat tgttcgacaa ttagctgctt caaaacataa 1700

 tgtgcattgc ttatgaatgc cttcatatac taatacagat actctgataa 1750

 tattacactc taataaggat aatgctgaat tttgaaagga cacaaaacat 1800

 ctaatgccaa tatatacatg gttagccaac atctttgcta tcaagaccac 1850

 ttgttttaaa taaagatgca agtgtcagtt gtagattatt gggatgaagc 1900

 taaatcccca gaatgcagca gcagctgagc atgttaaaat ggggaaggat 1950

 gatagctaca tgtatgccgg tcctactcac gcgacacccg tgtgctcaaa 2000

 aaagttactt gtttttgtta cgtgtgattt tcctatttct ctagcccaaa 2050

 gtgcattaca gaagatacac ctatagaacc attaccttct gctatgtgtg 2100

 ccagggctca tctactcctg tacattaatg gattacttta gatgcaaatg 2150

 cagattacaa tggagtgggg aagtactttc attacccaag cctcagaaaa 2200

 acacacaaga acaataacac agcaaacaga ttgagggatt gttgtggttt 2250

 ttgactaagg tgtatgttag tttcatcaga aacttaaaac atagactgat 2300

 cactcagaaa ttaaagtccg ttttactgtg aatatagcaa tatagtactg 2350

 gacacagtac tggtgaaact gaggagagca ttgcttgtaa aatcctgagt 2400

 ttccataagg aaaatgaaaa ctccttttaa aaataaaatc tgaggagtgt 2450

 acaataagca tatgctttga ctttcctttg ctgtggaggt ttttggtttt 2500

 tcattgatga taaacgacta cagacttagt agtggagaaa tggtgtcctc 2550

 tagtggaaga aatagtagct ccgctattca gatgcagagc actgcagcat 2600

 ccagcctttc aaagctgact cttctcaatc atctgtgggt catttgactt 2650

 gattttttaa gctaccctga atttccagaa tgcaggttct aaagaaatct 2700

 agatgagaga aagtatttga aaatgatttt taaatgtttt ttaaaagaca 2750

 catctgacat ttttaacaac ttagtaaaag ttgaaatgac cattctgtgt 2800

 agtcataaaa gaaacacaat gaagtgtatg gcctctggag ttagtcttag 2850

 taaaacttat tgctctgtgt caatgttaac ctgtctcaga tcaagtaatt 2900

 ccttcactag gttgggtttg gggagggggg aaaagagggg cttttcctag 2950

 gagaacgata agaaatggaa agactccttg aagtgttgca agggaacctc 3000

 ctagcactgt gaaagtcaga atcgcctcag catttccatg acgcacatta 3050

 tgcaaatctc tttagcacta ttttaaggtt gaaaacttta acaatgaagg 3100

 ggaaggggaa gatttccacc aactgaatca tttgtgcacg tgtatagctc 3150

 aaagagctta gacttcaaat atatctggtg aatg 3184

<210> 892
<211> 192
<212> PRT
<213> Homo sapien

<400> 892
 Met Asp Cys Asp Val Ser Thr Leu Val Ala Cys Val Val Asp Val
   1               5                  10                  15

 Glu Val Phe Thr Asn Gln Glu Val Lys Glu Lys Phe Gly Gly Leu
                  20                  25                  30

 Phe Arg Thr Tyr Asp Asp Cys Val Thr Phe Gln Leu Phe Lys Ser
                  35                  40                  45

 Phe Arg Arg Val Arg Ile Asn Phe Ser Asn Pro Lys Ser Ala Ala
                  50                  55                  60

 Arg Ala Arg Ile Glu Leu His Glu Thr Gln Phe Arg Gly Lys Lys
                  65                  70                  75

 Leu Lys Leu Tyr Phe Ala Gln Val Gln Thr Pro Glu Thr Asp Gly
                  80                  85                  90

 Asp Lys Leu His Leu Ala Pro Pro Gln Pro Ala Lys Gln Phe Leu
                  95                 100                 105

 Ile Ser Pro Pro Ser Ser Pro Pro Val Ser Trp Gln Pro Ile Asn
                 110                 115                 120

 Asp Ala Thr Pro Val Leu Asn Tyr Asp Leu Leu Tyr Ala Val Ala
                 125                 130                 135

 Lys Leu Gly Pro Gly Glu Lys Tyr Glu Leu His Ala Gly Thr Glu
                 140                 145                 150

 Ser Thr Pro Ser Val Val Val His Val Cys Asp Ser Asp Ile Glu
                 155                 160                 165

 Glu Glu Glu Asp Pro Lys Thr Ser Pro Lys Pro Lys Ile Ile Gln
                 170                 175                 180

 Thr Arg Arg Pro Gly Leu Pro Pro Ser Val Ser Asn
                 185                 190

<210> 893
<211> 10412
<212> DNA
<213> Homo sapien

<400> 893
 gtaattgcga gcgagagtga gtggggccgg gacccgcaga gccgagccga 50

 cccttctctc ccgggctgcg gcagggcagg gcggggagct ccgcgcacca 100

 acagagccgg ttctcagggc gctttgctcc ttgttttttc cccggttctg 150

 ttttctcccc ttctccggaa ggcttgtcaa ggggtaggag aaagagacgc 200

 aaacacaaaa gtggaaaaca gttaatgacc agccacggcg tccctgctgt 250

 gagctctggc cgctgccttc cagggctccc gagccacacg ctgggggtgc 300

 tggctgaggg aacatggctt gttggcctca gctgaggttg ctgctgtgga 350

 agaacctcac tttcagaaga agacaaacat gtcagctgct gctggaagtg 400

 gcctggcctc tatttatctt cctgatcctg atctctgttc ggctgagcta 450

 cccaccctat gaacaacatg aatgccattt tccaaataaa gccatgccct 500

 ctgcaggaac acttccttgg gttcagggga ttatctgtaa tgccaacaac 550

 ccctgtttcc gttacccgac tcctggggag gctcccggag ttgttggaaa 600

 ctttaacaaa tccattgtgg ctcgcctgtt ctcagatgct cggaggcttc 650

 ttttatacag ccagaaagac accagcatga aggacatgcg caaagttctg 700

 agaacattac agcagatcaa gaaatccagc tcaaacttga agcttcaaga 750

 tttcctggtg gacaatgaaa ccttctctgg gttcctgtat cacaacctct 800

 ctctcccaaa gtctactgtg gacaagatgc tgagggctga tgtcattctc 850

 cacaaggtat ttttgcaagg ctaccagtta catttgacaa gtctgtgcaa 900

 tggatcaaaa tcagaagaga tgattcaact tggtgaccaa gaagtttctg 950

 agctttgtgg cctaccaagg gagaaactgg ctgcagcaga gcgagtactt 1000

 cgttccaaca tggacatcct gaagccaatc ctgagaacac taaactctac 1050

 atctcccttc ccgagcaagg agctggctga agccacaaaa acattgctgc 1100

 atagtcttgg gactctggcc caggagctgt tcagcatgag aagctggagt 1150

 gacatgcgac aggaggtgat gtttctgacc aatgtgaaca gctccagctc 1200

 ctccacccaa atctaccagg ctgtgtctcg tattgtctgc gggcatcccg 1250

 agggaggggg gctgaagatc aagtctctca actggtatga ggacaacaac 1300

 tacaaagccc tctttggagg caatggcact gaggaagatg ctgaaacctt 1350

 ctatgacaac tctacaactc cttactgcaa tgatttgatg aagaatttgg 1400

 agtctagtcc tctttcccgc attatctgga aagctctgaa gccgctgctc 1450

 gttgggaaga tcctgtatac acctgacact ccagccacaa ggcaggtcat 1500

 ggctgaggtg aacaagacct tccaggaact ggctgtgttc catgatctgg 1550

 aaggcatgtg ggaggaactc agccccaaga tctggacctt catggagaac 1600

 agccaagaaa tggaccttgt ccggatgctg ttggacagca gggacaatga 1650

 ccacttttgg gaacagcagt tggatggctt agattggaca gcccaagaca 1700

 tcgtggcgtt tttggccaag cacccagagg atgtccagtc cagtaatggt 1750

 tctgtgtaca cctggagaga agctttcaac gagactaacc aggcaatccg 1800

 gaccatatct cgcttcatgg agtgtgtcaa cctgaacaag ctagaaccca 1850

 tagcaacaga agtctggctc atcaacaagt ccatggagct gctggatgag 1900

 aggaagttct gggctggtat tgtgttcact ggaattactc caggcagcat 1950

 tgagctgccc catcatgtca agtacaagat ccgaatggac attgacaatg 2000

 tggagaggac aaataaaatc aaggatgggt actgggaccc tggtcctcga 2050

 gctgacccct ttgaggacat gcggtacgtc tgggggggct tcgcctactt 2100

 gcaggatgtg gtggagcagg caatcatcag ggtgctgacg ggcaccgaga 2150

 agaaaactgg tgtctatatg caacagatgc cctatccctg ttacgttgat 2200

 gacatctttc tgcgggtgat gagccggtca atgcccctct tcatgacgct 2250

 ggcctggatt tactcagtgg ctgtgatcat caagggcatc gtgtatgaga 2300

 aggaggcacg gctgaaagag accatgcgga tcatgggcct ggacaacagc 2350

 atcctctggt ttagctggtt cattagtagc ctcattcctc ttcttgtgag 2400

 cgctggcctg ctagtggtca tcctgaagtt aggaaacctg ctgccctaca 2450

 gtgatcccag cgtggtgttt gtcttcctgt ccgtgtttgc tgtggtgaca 2500

 atcctgcagt gcttcctgat tagcacactc ttctccagag ccaacctggc 2550

 agcagcctgt gggggcatca tctacttcac gctgtacctg ccctacgtcc 2600

 tgtgtgtggc atggcaggac tacgtgggct tcacactcaa gatcttcgct 2650

 agcctgctgt ctcctgtggc ttttgggttt ggctgtgagt actttgccct 2700

 ttttgaggag cagggcattg gagtgcagtg ggacaacctg tttgagagtc 2750

 ctgtggagga agatggcttc aatctcacca cttcggtctc catgatgctg 2800

 tttgacacct tcctctatgg ggtgatgacc tggtacattg aggctgtctt 2850

 tccaggccag tacggaattc ccaggccctg gtattttcct tgcaccaagt 2900

 cctactggtt tggcgaggaa agtgatgaga agagccaccc tggttccaac 2950

 cagaagagaa tatcagaaat ctgcatggag gaggaaccca cccacttgaa 3000

 gctgggcgtg tccattcaga acctggtaaa agtctaccga gatgggatga 3050

 aggtggctgt cgatggcctg gcactgaatt tttatgaggg ccagatcacc 3100

 tccttcctgg gccacaatgg agcggggaag acgaccacca tgtcaatcct 3150

 gaccgggttg ttccccccga cctcgggcac cgcctacatc ctgggaaaag 3200

 acattcgctc tgagatgagc accatccggc agaacctggg ggtctgtccc 3250

 cagcataacg tgctgtttga catgctgact gtcgaagaac acatctggtt 3300

 ctatgcccgc ttgaaagggc tctctgagaa gcacgtgaag gcggagatgg 3350

 agcagatggc cctggatgtt ggtttgccat caagcaagct gaaaagcaaa 3400

 acaagccagc tgtcaggtgg aatgcagaga aagctatctg tggccttggc 3450

 ctttgtcggg ggatctaagg ttgtcattct ggatgaaccc acagctggtg 3500

 tggaccctta ctcccgcagg ggaatatggg agctgctgct gaaataccga 3550

 caaggccgca ccattattct ctctacacac cacatggatg aagcggacgt 3600

 cctgggggac aggattgcca tcatctccca tgggaagctg tgctgtgtgg 3650

 gctcctccct gtttctgaag aaccagctgg gaacaggcta ctacctgacc 3700

 ttggtcaaga aagatgtgga atcctccctc agttcctgca gaaacagtag 3750

 tagcactgtg tcatacctga aaaaggagga cagtgtttct cagagcagtt 3800

 ctgatgctgg cctgggcagc gaccatgaga gtgacacgct gaccatcgat 3850

 gtctctgcta tctccaacct catcaggaag catgtgtctg aagcccggct 3900

 ggtggaagac atagggcatg agctgaccta tgtgctgcca tatgaagctg 3950

 ctaaggaggg agcctttgtg gaactctttc atgagattga tgaccggctc 4000

 tcagacctgg gcatttctag ttatggcatc tcagagacga ccctggaaga 4050

 aatattcctc aaggtggccg aagagagtgg ggtggatgct gagacctcag 4100

 atggtacctt gccagcaaga cgaaacaggc gggccttcgg ggacaagcag 4150

 agctgtcttc gcccgttcac tgaagatgat gctgctgatc caaatgattc 4200

 tgacatagac ccagaatcca gagagacaga cttgctcagt gggatggatg 4250

 gcaaagggtc ctaccaggtg aaaggctgga aacttacaca gcaacagttt 4300

 gtggcccttt tgtggaagag actgctaatt gccagacgga gtcggaaagg 4350

 attttttgct cagattgtct tgccagctgt gtttgtctgc attgcccttg 4400

 tgttcagcct gatcgtgcca ccctttggca agtaccccag cctggaactt 4450

 cagccctgga tgtacaacga acagtacaca tttgtcagca atgatgctcc 4500

 tgaggacacg ggaaccctgg aactcttaaa cgccctcacc aaagaccctg 4550

 gcttcgggac ccgctgtatg gaaggaaacc caatcccaga cacgccctgc 4600

 caggcagggg aggaagagtg gaccactgcc ccagttcccc agaccatcat 4650

 ggacctcttc cagaatggga actggacaat gcagaaccct tcacctgcat 4700

 gccagtgtag cagcgacaaa atcaagaaga tgctgcctgt gtgtccccca 4750

 ggggcagggg ggctgcctcc tccacaaaga aaacaaaaca ctgcagatat 4800

 ccttcaggac ctgacaggaa gaaacatttc ggattatctg gtgaagacgt 4850

 atgtgcagat catagccaaa agcttaaaga acaagatctg ggtgaatgag 4900

 tttaggtatg gcggcttttc cctgggtgtc agtaatactc aagcacttcc 4950

 tccgagtcaa gaagttaatg atgccatcaa acaaatgaag aaacacctaa 5000

 agctggccaa ggacagttct gcagatcgat ttctcaacag cttgggaaga 5050

 tttatgacag gactggacac caaaaataat gtcaaggtgt ggttcaataa 5100

 caagggctgg catgcaatca gctctttcct gaatgtcatc aacaatgcca 5150

 ttctccgggc caacctgcaa aagggagaga accctagcca ttatggaatt 5200

 actgctttca atcatcccct gaatctcacc aagcagcagc tctcagaggt 5250

 ggctctgatg accacatcag tggatgtcct tgtgtccatc tgtgtcatct 5300

 ttgcaatgtc cttcgtccca gccagctttg tcgtattcct gatccaggag 5350

 cgggtcagca aagcaaaaca cctgcagttc atcagtggag tgaagcctgt 5400

 catctactgg ctctctaatt ttgtctggga tatgtgcaat tacgttgtcc 5450

 ctgccacact ggtcattatc atcttcatct gcttccagca gaagtcctat 5500

 gtgtcctcca ccaatctgcc tgtgctagcc cttctacttt tgctgtatgg 5550

 gtggtcaatc acacctctca tgtacccagc ctcctttgtg ttcaagatcc 5600

 ccagcacagc ctatgtggtg ctcaccagcg tgaacctctt cattggcatt 5650

 aatggcagcg tggccacctt tgtgctggag ctgttcaccg acaataagct 5700

 gaataatatc aatgatatcc tgaagtccgt gttcttgatc ttcccacatt 5750

 tttgcctggg acgagggctc atcgacatgg tgaaaaacca ggcaatggct 5800

 gatgccctgg aaaggtttgg ggagaatcgc tttgtgtcac cattatcttg 5850

 ggacttggtg ggacgaaacc tcttcgccat ggccgtggaa ggggtggtgt 5900

 tcttcctcat tactgttctg atccagtaca gattcttcat caggcccaga 5950

 cctgtaaatg caaagctatc tcctctgaat gatgaagatg aagatgtgag 6000

 gcgggaaaga cagagaattc ttgatggtgg aggccagaat gacatcttag 6050

 aaatcaagga gttgacgaag atatatagaa ggaagcggaa gcctgctgtt 6100

 gacaggattt gcgtgggcat tcctcctggt gagtgctttg ggctcctggg 6150

 agttaatggg gctggaaaat catcaacttt caagatgtta acaggagata 6200

 ccactgttac cagaggagat gctttcctta acaaaaatag tatcttatca 6250

 aacatccatg aagtacatca gaacatgggc tactgccctc agtttgatgc 6300

 catcacagag ctgttgactg ggagagaaca cgtggagttc tttgcccttt 6350

 tgagaggagt cccagagaaa gaagttggca aggttggtga gtgggcgatt 6400

 cggaaactgg gcctcgtgaa gtatggagaa aaatatgctg gtaactatag 6450

 tggaggcaac aaacgcaagc tctctacagc catggctttg atcggcgggc 6500

 ctcctgtggt gtttctggat gaacccacca caggcatgga tcccaaagcc 6550

 cggcggttct tgtggaattg tgccctaagt gttgtcaagg aggggagatc 6600

 agtagtgctt acatctcata gtatggaaga atgtgaagct ctttgcacta 6650

 ggatggcaat catggtcaat ggaaggttca ggtgccttgg cagtgtccag 6700

 catctaaaaa ataggtttgg agatggttat acaatagttg tacgaatagc 6750

 agggtccaac ccggacctga agcctgtcca ggatttcttt ggacttgcat 6800

 ttcctggaag tgttctaaaa gagaaacacc ggaacatgct acaataccag 6850

 cttccatctt cattatcttc tctggccagg atattcagca tcctctccca 6900

 gagcaaaaag cgactccaca tagaagacta ctctgtttct cagacaacac 6950

 ttgaccaagt atttgtgaac tttgccaagg accaaagtga tgatgaccac 7000

 ttaaaagacc tctcattaca caaaaaccag acagtagtgg acgttgcagt 7050

 tctcacatct tttctacagg atgagaaagt gaaagaaagc tatgtatgaa 7100

 gaatcctgtt catacggggt ggctgaaagt aaagaggaac tagactttcc 7150

 tttgcaccat gtgaagtgtt gtggagaaaa gagccagaag ttgatgtggg 7200

 aagaagtaaa ctggatactg tactgatact attcaatgca atgcaattca 7250

 atgcaatgaa aacaaaattc cattacaggg gcagtgcctt tgtagcctat 7300

 gtcttgtatg gctctcaagt gaaagacttg aatttagttt tttacctata 7350

 cctatgtgaa actctattat ggaacccaat ggacatatgg gtttgaactc 7400

 acactttttt tttttttttt gttcctgtgt attctcattg gggttgcaac 7450

 aataattcat caagtaatca tggccagcga ttattgatca aaatcaaaag 7500

 gtaatgcaca tcctcattca ctaagccatg ccatgcccag gagactggtt 7550

 tcccggtgac acatccattg ctggcaatga gtgtgccaga gttattagtg 7600

 ccaagttttt cagaaagttt gaagcaccat ggtgtgtcat gctcactttt 7650

 gtgaaagctg ctctgctcag agtctatcaa cattgaatat cagttgacag 7700

 aatggtgcca tgcgtggcta acatcctgct ttgattccct ctgataagct 7750

 gttctggtgg cagtaacatg caacaaaaat gtgggtgtct ccaggcacgg 7800

 gaaacttggt tccattgtta tattgtccta tgcttcgagc catgggtcta 7850

 cagggtcatc cttatgagac tcttaaatat acttagatcc tggtaagagg 7900

 caaagaatca acagccaaac tgctggggct gcaagctgct gaagccaggg 7950

 catgggatta aagagattgt gcgttcaaac ctagggaagc ctgtgcccat 8000

 ttgtcctgac tgtctgctaa catggtacac tgcatctcaa gatgtttatc 8050

 tgacacaagt gtattatttc tggctttttg aattaatcta gaaaatgaaa 8100

 agatggagtt gtattttgac aaaaatgttt gtacttttta atgttatttg 8150

 gaattttaag ttctatcagt gacttctgaa tccttagaat ggcctctttg 8200

 tagaaccctg tggtatagag gagtatggcc actgccccac tatttttatt 8250

 ttcttatgta agtttgcata tcagtcatga ctagtgccta gaaagcaatg 8300

 tgatggtcag gatctcatga cattatattt gagtttcttt cagatcattt 8350

 aggatactct taatctcact tcatcaatca aatatttttt gagtgtatgc 8400

 tgtagctgaa agagtatgta cgtacgtata agactagaga gatattaagt 8450

 ctcagtacac ttcctgtgcc atgttattca gctcactggt ttacaaatat 8500

 aggttgtctt gtggttgtag gagcccactg taacaatact gggcagcctt 8550

 tttttttttt tttttaattg caacaatgca aaagccaaga aagtataagg 8600

 gtcacaagtc taaacaatga attcttcaac agggaaaaca gctagcttga 8650

 aaacttgctg aaaaacacaa cttgtgttta tggcatttag taccttcaaa 8700

 taattggctt tgcagatatt ggatacccca ttaaatctga cagtctcaaa 8750

 tttttcatct cttcaatcac tagtcaagaa aaatataaaa acaacaaata 8800

 cttccatatg gagcattttt cagagttttc taacccagtc ttatttttct 8850

 agtcagtaaa catttgtaaa aatactgttt cactaatact tactgttaac 8900

 tgtcttgaga gaaaagaaaa atatgagaga actattgttt ggggaagttc 8950

 aagtgatctt tcaatatcat tactaacttc ttccactttt tccagaattt 9000

 gaatattaac gctaaaggtg taagacttca gatttcaaat taatctttct 9050

 atatttttta aatttacaga atattatata acccactgct gaaaaagaaa 9100

 aaaatgattg ttttagaagt taaagtcaat attgatttta aatataagta 9150

 atgaaggcat atttccaata actagtgata tggcatcgtt gcattttaca 9200

 gtatcttcaa aaatacagaa tttatagaat aatttctcct catttaatat 9250

 ttttcaaaat caaagttatg gtttcctcat tttactaaaa tcgtattcta 9300

 attcttcatt atagtaaatc tatgagcaac tccttacttc ggttcctctg 9350

 atttcaaggc catattttaa aaaatcaaaa ggcactgtga actattttga 9400

 agaaaacaca acattttaat acagattgaa aggacctctt ctgaagctag 9450

 aaacaatcta tagttataca tcttcattaa tactgtgtta ccttttaaaa 9500

 tagtaatttt ttacattttc ctgtgtaaac ctaattgtgg tagaaatttt 9550

 taccaactct atactcaatc aagcaaaatt tctgtatatt ccctgtggaa 9600

 tgtacctatg tgagtttcag aaattctcaa aatacgtgtt caaaaatttc 9650

 tgcttttgca tctttgggac acctcagaaa acttattaac aactgtgaat 9700

 atgagaaata cagaagaaaa taataagccc tctatacata aatgcccagc 9750

 acaattcatt gttaaaaaac aaccaaacct cacactactg tatttcatta 9800

 tctgtactga aagcaaatgc tttgtgacta ttaaatgttg cacatcattc 9850

 attcactgta tagtaatcat tgactaaagc catttgtctg tgttttcttc 9900

 ttgtggttgt atatatcagg taaaatattt tccaaagagc catgtgtcat 9950

 gtaatactga accactttga tattgagaca ttaatttgta cccttgttat 10000

 tatctactag taataatgta atactgtaga aatattgctc taattctttt 10050

 caaaattgtt gcatccccct tagaatgttt ctatttccat aaggatttag 10100

 gtatgctatt atcccttctt ataccctaag atgaagctgt ttttgtgctc 10150

 tttgttcatc attggccctc attccaagca ctttacgctg tctgtaatgg 10200

 gatctatttt tgcactggaa tatctgagaa ttgcaaaact agacaaaagt 10250

 ttcacaacag atttctaagt taaatcattt tcattaaaag gaaaaaagaa 10300

 aaaaaatttt gtatgtcaat aactttatat gaagtattaa aatgcatatt 10350

 tctatgttgt aatataatga gtcacaaaat aaagctgtga cagttctgtt 10400

 ggtctacaga aa 10412

<210> 894
<211> 2000
<212> PRT
<213> Homo sapien

<400> 894
 Met Ala Cys Trp Pro Gln Leu Arg Leu Leu Leu Trp Lys Asn Leu
   1               5                  10                  15

 Thr Phe Arg Arg Arg Gln Thr Cys Gln Leu Leu Leu Glu Val Ala
                  20                  25                  30

 Trp Pro Leu Phe Ile Phe Leu Ile Leu Ile Ser Val Arg Leu Ser
                  35                  40                  45

 Tyr Pro Pro Tyr Glu Gln His Glu Cys His Phe Pro Asn Lys Ala
                  50                  55                  60

 Met Pro Ser Ala Gly Thr Leu Pro Trp Val Gln Gly Ile Ile Cys
                  65                  70                  75

 Asn Ala Asn Asn Pro Cys Phe Arg Tyr Pro Thr Pro Gly Glu Ala
                  80                  85                  90

 Pro Gly Val Val Gly Asn Phe Asn Lys Ser Ile Val Ala Arg Leu
                  95                 100                 105

 Phe Ser Asp Ala Arg Arg Leu Leu Leu Tyr Ser Gln Lys Asp Thr
                 110                 115                 120

 Ser Met Lys Asp Met Arg Lys Val Leu Arg Thr Leu Gln Gln Ile
                 125                 130                 135

 Lys Lys Ser Ser Ser Asn Leu Lys Leu Gln Asp Phe Leu Val Asp
                 140                 145                 150

 Asn Glu Thr Phe Ser Gly Phe Leu Tyr His Asn Leu Ser Leu Pro
                 155                 160                 165

 Lys Ser Thr Val Asp Lys Met Leu Arg Ala Asp Val Ile Leu His
                 170                 175                 180

 Lys Val Phe Leu Gln Gly Tyr Gln Leu His Leu Thr Ser Leu Cys
                 185                 190                 195

 Asn Gly Ser Lys Ser Glu Glu Met Ile Gln Leu Gly Asp Gln Glu
                 200                 205                 210

 Val Ser Glu Leu Cys Gly Leu Pro Arg Glu Lys Leu Ala Ala Ala
                 215                 220                 225

 Glu Arg Val Leu Arg Ser Asn Met Asp Ile Leu Lys Pro Ile Leu
                 230                 235                 240

 Arg Thr Leu Asn Ser Thr Ser Pro Phe Pro Ser Lys Glu Leu Ala
                 245                 250                 255

 Glu Ala Thr Lys Thr Leu Leu His Ser Leu Gly Thr Leu Ala Gln
                 260                 265                 270

 Glu Leu Phe Ser Met Arg Ser Trp Ser Asp Met Arg Gln Glu Val
                 275                 280                 285

 Met Phe Leu Thr Asn Val Asn Ser Ser Ser Ser Ser Thr Gln Ile
                 290                 295                 300

 Tyr Gln Ala Val Ser Arg Ile Val Cys Gly His Pro Glu Gly Gly
                 305                 310                 315

 Gly Leu Lys Ile Lys Ser Leu Asn Trp Tyr Glu Asp Asn Asn Tyr
                 320                 325                 330

 Lys Ala Leu Phe Gly Gly Asn Gly Thr Glu Glu Asp Ala Glu Thr
                 335                 340                 345

 Phe Tyr Asp Asn Ser Thr Thr Pro Tyr Cys Asn Asp Leu Met Lys
                 350                 355                 360

 Asn Leu Glu Ser Ser Pro Leu Ser Arg Ile Ile Trp Lys Ala Leu
                 365                 370                 375

 Lys Pro Leu Leu Val Gly Lys Ile Leu Tyr Thr Pro Asp Thr Pro
                 380                 385                 390

 Ala Thr Arg Gln Val Met Ala Glu Val Asn Lys Thr Phe Gln Glu
                 395                 400                 405

 Leu Ala Val Phe His Asp Leu Glu Gly Met Trp Glu Glu Leu Ser
                 410                 415                 420

 Pro Lys Ile Trp Thr Phe Met Glu Asn Ser Gln Glu Met Asp Leu
                 425                 430                 435

 Val Arg Met Leu Leu Asp Ser Arg Asp Asn Asp His Phe Trp Glu
                 440                 445                 450

 Gln Gln Leu Asp Gly Leu Asp Trp Thr Ala Gln Asp Ile Val Ala
                 455                 460                 465

 Phe Leu Ala Lys His Pro Glu Asp Val Gln Ser Ser Asn Gly Ser
                 470                 475                 480

 Val Tyr Thr Trp Arg Glu Ala Phe Asn Glu Thr Asn Gln Ala Ile
                 485                 490                 495

 Arg Thr Ile Ser Arg Phe Met Glu Cys Val Asn Leu Asn Lys Leu
                 500                 505                 510

 Glu Pro Ile Ala Thr Glu Val Trp Leu Ile Asn Lys Ser Met Glu
                 515                 520                 525

 Leu Leu Asp Glu Arg Lys Phe Trp Ala Gly Ile Val Phe Thr Gly
                 530                 535                 540

 Ile Thr Pro Gly Ser Ile Glu Leu Pro His His Val Lys Tyr Lys
                 545                 550                 555

 Ile Arg Met Asp Ile Asp Asn Val Glu Arg Thr Asn Lys Ile Lys
                 560                 565                 570

 Asp Gly Tyr Trp Asp Pro Gly Pro Arg Ala Asp Pro Phe Glu Asp
                 575                 580                 585

 Met Arg Tyr Val Trp Gly Gly Phe Ala Tyr Leu Gln Asp Val Val
                 590                 595                 600

 Glu Gln Ala Ile Ile Arg Val Leu Thr Gly Thr Glu Lys Lys Thr
                 605                 610                 615

 Gly Val Tyr Met Gln Gln Met Pro Tyr Pro Cys Tyr Val Asp Asp
                 620                 625                 630

 Ile Phe Leu Arg Val Met Ser Arg Ser Met Pro Leu Phe Met Thr
                 635                 640                 645

 Leu Ala Trp Ile Tyr Ser Val Ala Val Ile Ile Lys Gly Ile Val
                 650                 655                 660

 Tyr Glu Lys Glu Ala Arg Leu Lys Glu Thr Met Arg Ile Met Gly
                 665                 670                 675

 Leu Asp Asn Ser Ile Leu Trp Phe Ser Trp Phe Ile Ser Ser Leu
                 680                 685                 690

 Ile Pro Leu Leu Val Ser Ala Gly Leu Leu Val Val Ile Leu Lys
                 695                 700                 705

 Leu Gly Asn Leu Leu Pro Tyr Ser Asp Pro Ser Val Val Phe Val
                 710                 715                 720

 Phe Leu Ser Val Phe Ala Val Val Thr Ile Leu Gln Cys Phe Leu
                 725                 730                 735

 Ile Ser Thr Leu Phe Ser Arg Ala Asn Leu Ala Ala Ala Cys Gly
                 740                 745                 750

 Gly Ile Ile Tyr Phe Thr Leu Tyr Leu Pro Tyr Val Leu Cys Val
                 755                 760                 765

 Ala Trp Gln Asp Tyr Val Gly Phe Thr Leu Lys Ile Phe Ala Ser
                 770                 775                 780

 Leu Leu Ser Pro Val Ala Phe Gly Phe Gly Cys Glu Tyr Phe Ala
                 785                 790                 795

 Leu Phe Glu Glu Gln Gly Ile Gly Val Gln Trp Asp Asn Leu Phe
                 800                 805                 810

 Glu Ser Pro Val Glu Glu Asp Gly Phe Asn Leu Thr Thr Ser Val
                 815                 820                 825

 Ser Met Met Leu Phe Asp Thr Phe Leu Tyr Gly Val Met Thr Trp
                 830                 835                 840

 Tyr Ile Glu Ala Val Phe Pro Gly Gln Tyr Gly Ile Pro Arg Pro
                 845                 850                 855

 Trp Tyr Phe Pro Cys Thr Lys Ser Tyr Trp Phe Gly Glu Glu Ser
                 860                 865                 870

 Asp Glu Lys Ser His Pro Gly Ser Asn Gln Lys Arg Ile Ser Glu
                 875                 880                 885

 Ile Cys Met Glu Glu Glu Pro Thr His Leu Lys Leu Gly Val Ser
                 890                 895                 900

 Ile Gln Asn Leu Val Lys Val Tyr Arg Asp Gly Met Lys Val Ala
                 905                 910                 915

 Val Asp Gly Leu Ala Leu Asn Phe Tyr Glu Gly Gln Ile Thr Ser
                 920                 925                 930

 Phe Leu Gly His Asn Gly Ala Gly Lys Thr Thr Thr Met Ser Ile
                 935                 940                 945

 Leu Thr Gly Leu Phe Pro Pro Thr Ser Gly Thr Ala Tyr Ile Leu
                 950                 955                 960

 Gly Lys Asp Ile Arg Ser Glu Met Ser Thr Ile Arg Gln Asn Leu
                 965                 970                 975

 Gly Val Cys Pro Gln His Asn Val Leu Phe Asp Met Leu Thr Val
                 980                 985                 990

 Glu Glu His Ile Trp Phe Tyr Ala Arg Leu Lys Gly Leu Ser Glu
                 995                1000                1005

 Lys His Val Lys Ala Glu Met Glu Gln Met Ala Leu Asp Val Gly
                1010                1015                1020

 Leu Pro Ser Ser Lys Leu Lys Ser Lys Thr Ser Gln Leu Ser Gly
                1025                1030                1035

 Gly Met Gln Arg Lys Leu Ser Val Ala Leu Ala Phe Val Gly Gly
                1040                1045                1050

 Ser Lys Val Val Ile Leu Asp Glu Pro Thr Ala Gly Val Asp Pro
                1055                1060                1065

 Tyr Ser Arg Arg Gly Ile Trp Glu Leu Leu Leu Lys Tyr Arg Gln
                1070                1075                1080

 Gly Arg Thr Ile Ile Leu Ser Thr His His Met Asp Glu Ala Asp
                1085                1090                1095

 Val Leu Gly Asp Arg Ile Ala Ile Ile Ser His Gly Lys Leu Cys
                1100                1105                1110

 Cys Val Gly Ser Ser Leu Phe Leu Lys Asn Gln Leu Gly Thr Gly
                1115                1120                1125

 Tyr Tyr Leu Thr Leu Val Lys Lys Asp Val Glu Ser Ser Leu Ser
                1130                1135                1140

 Ser Cys Arg Asn Ser Ser Ser Thr Val Ser Tyr Leu Lys Lys Glu
                1145                1150                1155

 Asp Ser Val Ser Gln Ser Ser Ser Asp Ala Gly Leu Gly Ser Asp
                1160                1165                1170

 His Glu Ser Asp Thr Leu Thr Ile Asp Val Ser Ala Ile Ser Asn
                1175                1180                1185

 Leu Ile Arg Lys His Val Ser Glu Ala Arg Leu Val Glu Asp Ile
                1190                1195                1200

 Gly His Glu Leu Thr Tyr Val Leu Pro Tyr Glu Ala Ala Lys Glu
                1205                1210                1215

 Gly Ala Phe Val Glu Leu Phe His Glu Ile Asp Asp Arg Leu Ser
                1220                1225                1230

 Asp Leu Gly Ile Ser Ser Tyr Gly Ile Ser Glu Thr Thr Leu Glu
                1235                1240                1245

 Glu Ile Phe Leu Lys Val Ala Glu Glu Ser Gly Val Asp Ala Glu
                1250                1255                1260

 Thr Ser Asp Gly Thr Leu Pro Ala Arg Arg Asn Arg Arg Ala Phe
                1265                1270                1275

 Gly Asp Lys Gln Ser Cys Leu Arg Pro Phe Thr Glu Asp Asp Ala
                1280                1285                1290

 Ala Asp Pro Asn Asp Ser Asp Ile Asp Pro Glu Ser Arg Glu Thr
                1295                1300                1305

 Asp Leu Leu Ser Gly Met Asp Gly Lys Gly Ser Tyr Gln Val Lys
                1310                1315                1320

 Gly Trp Lys Leu Thr Gln Gln Gln Phe Val Ala Leu Leu Trp Lys
                1325                1330                1335

 Arg Leu Leu Ile Ala Arg Arg Ser Arg Lys Gly Phe Phe Ala Gln
                1340                1345                1350

 Ile Val Leu Pro Ala Val Phe Val Cys Ile Ala Leu Val Phe Ser
                1355                1360                1365

 Leu Ile Val Pro Pro Phe Gly Lys Tyr Pro Ser Leu Glu Leu Gln
                1370                1375                1380

 Pro Trp Met Tyr Asn Glu Gln Tyr Thr Phe Val Ser Asn Asp Ala
                1385                1390                1395

 Pro Glu Asp Thr Gly Thr Leu Glu Leu Leu Asn Ala Leu Thr Lys
                1400                1405                1410

 Asp Pro Gly Phe Gly Thr Arg Cys Met Glu Gly Asn Pro Ile Pro
                1415                1420                1425

 Asp Thr Pro Cys Gln Ala Gly Glu Glu Glu Trp Thr Thr Ala Pro
                1430                1435                1440

 Val Pro Gln Thr Ile Met Asp Leu Phe Gln Asn Gly Asn Trp Thr
                1445                1450                1455

 Met Gln Asn Pro Ser Pro Ala Cys Gln Cys Ser Ser Asp Lys Ile
                1460                1465                1470

 Lys Lys Met Leu Pro Val Cys Pro Pro Gly Ala Gly Gly Leu Pro
                1475                1480                1485

 Pro Pro Gln Arg Lys Gln Asn Thr Ala Asp Ile Leu Gln Asp Leu
                1490                1495                1500

 Thr Gly Arg Asn Ile Ser Asp Tyr Leu Val Lys Thr Tyr Val Gln
                1505                1510                1515

 Ile Ile Ala Lys Ser Leu Lys Asn Lys Ile Trp Val Asn Glu Phe
                1520                1525                1530

 Arg Tyr Gly Gly Phe Ser Leu Gly Val Ser Asn Thr Gln Ala Leu
                1535                1540                1545

 Pro Pro Ser Gln Glu Val Asn Asp Ala Ile Lys Gln Met Lys Lys
                1550                1555                1560

 His Leu Lys Leu Ala Lys Asp Ser Ser Ala Asp Arg Phe Leu Asn
                1565                1570                1575

 Ser Leu Gly Arg Phe Met Thr Gly Leu Asp Thr Lys Asn Asn Val
                1580                1585                1590

 Lys Val Trp Phe Asn Asn Lys Gly Trp His Ala Ile Ser Ser Phe
                1595                1600                1605

 Leu Asn Val Ile Asn Asn Ala Ile Leu Arg Ala Asn Leu Gln Lys
                1610                1615                1620

 Gly Glu Asn Pro Ser His Tyr Gly Ile Thr Ala Phe Asn His Pro
                1625                1630                1635

 Leu Asn Leu Thr Lys Gln Gln Leu Ser Glu Val Ala Leu Met Thr
                1640                1645                1650

 Thr Ser Val Asp Val Leu Val Ser Ile Cys Val Ile Phe Ala Met
                1655                1660                1665

 Ser Phe Val Pro Ala Ser Phe Val Val Phe Leu Ile Gln Glu Arg
                1670                1675                1680

 Val Ser Lys Ala Lys His Leu Gln Phe Ile Ser Gly Val Lys Pro
                1685                1690                1695

 Val Ile Tyr Trp Leu Ser Asn Phe Val Trp Asp Met Cys Asn Tyr
                1700                1705                1710

 Val Val Pro Ala Thr Leu Val Ile Ile Ile Phe Ile Cys Phe Gln
                1715                1720                1725

 Gln Lys Ser Tyr Val Ser Ser Thr Asn Leu Pro Val Leu Ala Leu
                1730                1735                1740

 Leu Leu Leu Leu Tyr Gly Trp Ser Ile Thr Pro Leu Met Tyr Pro
                1745                1750                1755

 Ala Ser Phe Val Phe Lys Ile Pro Ser Thr Ala Tyr Val Val Leu
                1760                1765                1770

 Thr Ser Val Asn Leu Phe Ile Gly Ile Asn Gly Ser Val Ala Thr
                1775                1780                1785

 Phe Val Leu Glu Leu Phe Thr Asp Asn Lys Leu Asn Asn Ile Asn
                1790                1795                1800

 Asp Ile Leu Lys Ser Val Phe Leu Ile Phe Pro His Phe Cys Leu
                1805                1810                1815

 Gly Arg Gly Leu Ile Asp Met Val Lys Asn Gln Ala Met Ala Asp
                1820                1825                1830

 Ala Leu Glu Arg Phe Gly Glu Asn Arg Phe Val Ser Pro Leu Ser
                1835                1840                1845

 Trp Asp Leu Val Gly Arg Asn Leu Phe Ala Met Ala Val Glu Gly
                1850                1855                1860

 Val Val Phe Phe Leu Ile Thr Val Leu Ile Gln Tyr Arg Phe Phe
                1865                1870                1875

 Ile Arg Pro Arg Pro Val Asn Ala Lys Leu Ser Pro Leu Asn Asp
                1880                1885                1890

 Glu Asp Glu Asp Val Arg Arg Glu Arg Gln Arg Ile Leu Asp Gly
                1895                1900                1905

 Gly Gly Gln Asn Asp Ile Leu Glu Ile Lys Glu Leu Thr Lys Ile
                1910                1915                1920

 Tyr Arg Arg Lys Arg Lys Pro Ala Val Asp Arg Ile Cys Val Gly
                1925                1930                1935

 Ile Pro Pro Gly Glu Cys Phe Gly Leu Leu Gly Val Asn Gly Ala
                1940                1945                1950

 Gly Lys Ser Ser Thr Phe Lys Met Leu Thr Gly Asp Thr Thr Val
                1955                1960                1965

 Thr Arg Gly Asp Ala Phe Leu Asn Lys Asn Ser Ile Leu Ser Asn
                1970                1975                1980

 Ile His Glu Val His Gln Asn Met Gly Tyr Cys Pro Gln Phe Asp
                1985                1990                1995

 Ala Ile Thr Glu Leu
                2000

<210> 895
<211> 10442
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 9881, 9884, 9999, 10046
<223> Unknown base

<400> 895
 ggccgggacc cgcagagccg agccgaccct tctctcccgg gctgcggcag 50

 ggcagggcgg ggagctccgc gcaccaacag agccggttct cagggcgctt 100

 tgctccttgt tttttccccg gttctgtttt ctccccttct ccggaaggct 150

 tgtcaagggg taggagaaag agacgcaaac acaaaagtgg aaaacagtta 200

 atgaccagcc acgggcgtcc ctgctgtgag ctctggccgc tgccttccag 250

 ggctcccgag ccacacgctg ggcgtgctgg ctgagggaac atggcttgtt 300

 ggcctcagct gaggttgctg ctgtggaaga acctcacttt cagaagaaga 350

 caaacatgtc agctgttact ggaagtggcc tggcctctat ttatcttcct 400

 gatcctgatc tctgttcggc tgagctaccc accctatgaa caacatgaat 450

 gccattttcc aaataaagcc atgccctctg caggaacact tccttgggtt 500

 caggggatta tctgtaatgc caacaacccc tgtttccgtt acccgactcc 550

 tggggaggct cccggagttg ttggaaactt taacaaatcc attgtggctc 600

 gcctgttctc agatgctcgg aggcttcttt tatacagcca gaaagacacc 650

 agcatgaagg acatgcgcaa agttctgaga acattacagc agatcaagaa 700

 atccagctca aacttgaagc ttcaagattt cctggtggac aatgaaacct 750

 tctctgggtt cctatatcac aacctctctc tcccaaagtc tactgtggac 800

 aagatgctga gggctgatgt cattctccac aaggtatttt tgcaaggcta 850

 ccagttacat ttgacaagtc tgtgcaatgg atcaaaatca gaagagatga 900

 ttcaacttgg tgaccaagaa gtttctgagc tttgtggcct accaaaggag 950

 aaactggctg cagcagagcg agtacttcgt tccaacatgg acatcctgaa 1000

 gccaatcctg agaacactaa actctacatc tcccttcccg agcaaggagc 1050

 tggctgaagc cacaaaaaca ttgctgcata gtcttgggac tctggcccag 1100

 gagctgttca gcatgagaag ctggagtgac atgcgacagg aggtgatgtt 1150

 tctgaccaat gtgaacagct ccagctcctc cacccaaatc taccaggctg 1200

 tgtctcgtat tgtctgcggg catcccgagg gaggggggct gaagatcaag 1250

 tctctcaact ggtatgagga caacaactac aaagccctct ttggaggcaa 1300

 tggcactgag gaagatgctg aaaccttcta tgacaactct acaactcctt 1350

 actgcaatga tttgatgaag aatttggagt ctagtcctct ttcccgcatt 1400

 atctggaaag ctctgaagcc gctgctcgtt gggaagatcc tgtatacacc 1450

 tgacactcca gccacaaggc aggtcatggc tgaggtgaac aagaccttcc 1500

 aggaactggc tgtgttccat gatctggaag gcatgtggga ggaactcagc 1550

 cccaagatct ggaccttcat ggagaacagc caagaaatgg accttgtccg 1600

 gatgctgttg gacagcaggg acaatgacca cttttgggaa cagcagttgg 1650

 atggcttaga ttggacagcc caagacatcg tggcgttttt ggccaagcac 1700

 ccagaggatg tccagtccag taatggttct gtgtacacct ggagagaagc 1750

 tttcaacgag actaaccagg caatccggac catatctcgc ttcatggagt 1800

 gtgtcaacct gaacaagcta gaacccatag caacagaagt ctggctcatc 1850

 aacaagtcca tggagctgct ggatgagagg aagttctggg ctggtattgt 1900

 gttcactgga attactccag gcagcattga gctgccccat catgtcaagt 1950

 acaagatccg aatggacatt gacaatgtgg agaggacaaa taaaatcaag 2000

 gatgggtact gggaccctgg tcctcgagct gacccctttg aggacatgcg 2050

 gtacgtctgg gggggcttcg cctacttgca ggatgtggtg gagcaggcaa 2100

 tcatcagggt gctgacgggc accgagaaga aaactggtgt ctatatgcaa 2150

 cagatgccct atccctgtta cgttgatgac atctttctgc gggtgatgag 2200

 ccggtcaatg cccctcttca tgacgctggc ctggatttac tcagtggctg 2250

 tgatcatcaa gggcatcgtg tatgagaagg aggcacggct gaaagagacc 2300

 atgcggatca tgggcctgga caacagcata ctctggttta gctggttcat 2350

 tagtagcctc attcctcttc ttgtgagcgc tggcctgcta gtggtcatcc 2400

 tgaagttagg aaacctgctg ccctacagtg atcccagcgt ggtgtttgtc 2450

 ttcctgtccg tgtttgctgt ggtgacaatc ctgcagtgct tcctgattag 2500

 cacactcttc tccagagcca acctggcagc agcctgtggg ggcatcatct 2550

 acttcacgct gtacctgccc tacgtcctgt gtgtggcatg gcaggactac 2600

 gtgggcttca cactcaagat cttcgctagc ctgctgtctc ctgtggcttt 2650

 tgggtttggc tgtgagtact ttgccctttt tgaggagcag ggcattggag 2700

 tgcagtggga caacctgttt gagagtcctg tggaggaaga tggcttcaat 2750

 ctcaccactt cgatctccat gatgctgttt gacaccttcc tctatggggt 2800

 gatgacctgg tacattgagg ctgtctttcc aggccagtac ggaattccca 2850

 ggccctggta ttttccttgc accaagtcct actggtttgg cgaggaaagt 2900

 gatgagaaga gccaccctgg ttccaaccag aagagaatgt cagaaatctg 2950

 catggaggag gaacccaccc acttgaagct gggcgtgtcc attcagaacc 3000

 tggtaaaagt ctaccgagat gggatgaagg tggctgtcga tggcctggca 3050

 ctgaattttt atgagggcca gatcacctcc ttcctgggcc acaatggagc 3100

 ggggaagacg accaccatgt caatcctgac cgggttgttc cccccgacct 3150

 cgggcaccgc ctacatcctg ggaaaagaca ttcgctctga gatgagcacc 3200

 atccggcaga acctgggggt ctgtccccag cataacgtgc tgtttgacat 3250

 gctgactgtc gaagaacaca tctggttcta tgcccgcttg aaagggctct 3300

 ctgagaagca cgtgaaggcg gagatggagc agatggccct ggatgttggt 3350

 ttgccatcaa gcaagctgaa aagcaaaaca agccagctgt caggtggaat 3400

 gcagagaaag ctatctgtgg ccttggcctt tgtcggggga tctaaggttg 3450

 tcattctgga tgaacccaca gctggtgtgg acccttactc ccgcagggga 3500

 atatgggagc tgctgctgaa ataccgacaa ggccgcacca ttattctctc 3550

 tacacaccac atggatgaag cggacgtcct gggggacagg attgccatca 3600

 tctcccatgg gaagctgtgc tgtgtgggct cctccctgtt tctgaagaac 3650

 cagctgggaa caggctacta cctgaccttg gtcaagaaag atgtggaatc 3700

 ctccctcagt tcctgcagaa acagtagtag cactgtgtca tacctgaaaa 3750

 aggaggacag tgtttctcag agcagttctg atgctggcct gggcagcgac 3800

 catgagagtg acacgctgac catcgatgtc tctgctatct ccaacctcat 3850

 caggaagcat gtgtctgaag cccggctggt ggaagacata gggcatgagc 3900

 tgacctatgt gctgccatat gaagctgcta aggagggagc ctttgtggaa 3950

 ctctttcatg agattgatga ccggctctca gacctgggca tttctagtta 4000

 tggcatctca gagacgaccc tggaagaaat attcctcaag gtggccgaag 4050

 agagtggggt ggatgctgag acctcagatg gtaccttgcc agcaagacga 4100

 aacaggcggg ccttcgggga caagcagagc tgtcttcgcc cgttcactga 4150

 agatgatgct gctgatccaa atgattctga catagaccca gaatccagag 4200

 agacagactt gctcagtggg atggatggca aagggtccta ccaggtgaaa 4250

 ggctggaaac ttacacagca acagtttgtg gcccttttgt ggaagagact 4300

 gctaattgcc agacggagtc ggaaaggatt ttttgctcag attgtcttgc 4350

 cagctgtgtt tgtctgcatt gcccttgtgt tcagcctgat cgtgccaccc 4400

 tttggcaagt accccagcct ggaacttcag ccctggatgt acaacgaaca 4450

 gtacacattt gtcagcaatg atgctcctga ggacacggga accctggaac 4500

 tcttaaacgc cctcaccaaa gaccctggct tcgggacccg ctgtatggaa 4550

 ggaaacccaa tcccagacac gccctgccag gcaggggagg aagagtggac 4600

 cactgcccca gttccccaga ccatcatgga cctcttccag aatgggaact 4650

 ggacaatgca gaacccttca cctgcatgcc agtgtagcag cgacaaaatc 4700

 aagaagatgc tgcctgtgtg tcccccaggg gcaggggggc tgcctcctcc 4750

 acaaagaaaa caaaacactg cagatatcct tcaggacctg acaggaagaa 4800

 acatttcgga ttatctggtg aagacgtatg tgcagatcat agccaaaagc 4850

 ttaaagaaca agatctgggt gaatgagttt aggtatggcg gcttttccct 4900

 gggtgtcagt aatactcaag cacttcctcc gagtcaagaa gttaatgatg 4950

 ccatcaaaca aatgaagaaa cacctaaagc tggccaagga cagttctgca 5000

 gatcgatttc tcaacagctt gggaagattt atgacaggac tggacaccag 5050

 aaataatgtc aaggtgtggt tcaataacaa gggctggcat gcaatcagct 5100

 ctttcctgaa tgtcatcaac aatgccattc tccgggccaa cctgcaaaag 5150

 ggagagaacc ctagccatta tggaattact gctttcaatc atcccctgaa 5200

 tctcaccaag cagcagctct cagaggtggc tctgatgacc acatcagtgg 5250

 atgtccttgt gtccatctgt gtcatctttg caatgtcctt cgtcccagcc 5300

 agctttgtcg tattcctgat ccaggagcgg gtcagcaaag caaaacacct 5350

 gcagttcatc agtggagtga agcctgtcat ctactggctc tctaattttg 5400

 tctgggatat gtgcaattac gttgtccctg ccacactggt cattatcatc 5450

 ttcatctgct tccagcagaa gtcctatgtg tcctccacca atctgcctgt 5500

 gctagccctt ctacttttgc tgtatgggtg gtcaatcaca cctctcatgt 5550

 acccagcctc ctttgtgttc aagatcccca gcacagccta tgtggtgctc 5600

 accagcgtga acctcttcat tggcattaat ggcagcgtgg ccacctttgt 5650

 gctggagctg ttcaccgaca ataagctgaa taatatcaat gatatcctga 5700

 agtccgtgtt cttgatcttc ccacattttt gcctgggacg agggctcatc 5750

 gacatggtga aaaaccaggc aatggctgat gccctggaaa ggtttgggga 5800

 gaatcgcttt gtgtcaccat tatcttggga cttggtggga cgaaacctct 5850

 tcgccatggc cgtggaaggg gtggtgttct tcctcattac tgttctgatc 5900

 cagtacagat tcttcatcag gcccagacct gtaaatgcaa agctatctcc 5950

 tctgaatgat gaagatgaag atgtgaggcg ggaaagacag agaattcttg 6000

 atggtggagg ccagaatgac atcttagaaa tcaaggagtt gacgaagata 6050

 tatagaagga agcggaagcc tgctgttgac aggatttgcg tgggcattcc 6100

 tcctggtgag tgctttgggc tcctgggagt taatggggct ggaaaatcat 6150

 caactttcaa gatgttaaca ggagatacca ctgttaccag aggagatgct 6200

 ttccttaaca aaaatagtat cttatcaaac atccatgaag tacatcagaa 6250

 catgggctac tgccctcagt ttgatgccat cacagagctg ttgactggga 6300

 gagaacacgt ggagttcttt gcccttttga gaggagtccc agagaaagaa 6350

 gttggcaagg ttggtgagtg ggcgattcgg aaactgggcc tcgtgaagta 6400

 tggagaaaaa tatgctggta actatagtgg aggcaacaaa cgcaagctct 6450

 ctacagccat ggctttgatc ggcgggcctc ctgtggtgtt tctggatgaa 6500

 cccaccacag gcatggatcc caaagcccgg cggttcttgt ggaattgtgc 6550

 cctaagtgtt gtcaaggagg ggagatcagt agtgcttaca tctcatagta 6600

 tggaagaatg tgaagctctt tgcactagga tggcaatcat ggtcaatgga 6650

 aggttcaggt gccttggcag tgtccagcat ctaaaaaata ggtttggaga 6700

 tggttataca atagttgtac gaatagcagg gtccaacccg gacctgaagc 6750

 ctgtccagga tttctttgga cttgcatttc ctggaagtgt tctaaaagag 6800

 aaacaccgga acatgctaca ataccagctt ccatcttcat tatcttctct 6850

 ggccaggata ttcagcatcc tctcccagag caaaaagcga ctccacatag 6900

 aagactactc tgtttctcag acaacacttg accaagtatt tgtgaacttt 6950

 gccaaggacc aaagtgatga tgaccactta aaagacctct cattacacaa 7000

 aaaccagaca gtagtggacg ttgcagttct cacatctttt ctacaggatg 7050

 agaaagtgaa agaaagctat gtatgaagaa tcctgttcat acggggtggc 7100

 tgaaagtaaa gaggaactag actttccttt gcaccatgtg aagtgttgtg 7150

 gagaaaagag ccagaagttg atgtgggaag aagtaaactg gatactgtac 7200

 tgatactatt caatgcaatg caattcaatg caatgaaaac aaaattccat 7250

 tacaggggca gtgcctttgt agcctatgtc ttgtatggct ctcaagtgaa 7300

 agacttgaat ttagtttttt acctatacct atgtgaaact ctattatgga 7350

 acccaatgga catatgggtt tgaactcaca cttttttttt ttttttgttc 7400

 ctgtgtattc tcattggggt tgcaacaata attcatcaag taatcatggc 7450

 cagcgattat tgatcaaaat caaaaggtaa tgcacatcct cattcactaa 7500

 gccatgccat gcccaggaga ctggtttccc ggtgacacat ccattgctgg 7550

 caatgagtgt gccagagtta ttagtgccaa gtttttcaga aagtttgaag 7600

 caccatggtg tgtcatgctc acttttgtga aagctgctct gctcagagtc 7650

 tatcaacatt gaatatcagt tgacagaatg gtgccatgcg tggctaacat 7700

 cctgctttga ttccctctga taagctgttc tggtggcagt aacatgcaac 7750

 aaaaatgtgg gtgtctctag gcacgggaaa cttggttcca ttgttatatt 7800

 gtcctatgct tcgagccatg ggtctacagg gtcatcctta tgagactctt 7850

 aaatatactt agatcctggt aagaggcaaa gaatcaacag ccaaactgct 7900

 ggggctgcaa gctgctgaag ccagggcatg ggattaaaga gattgtgcgt 7950

 tcaaacctag ggaagcctgt gcccatttgt cctgactgtc tgctaacatg 8000

 gtacactgca tctcaagatg tttatctgac acaagtgtat tatttctggc 8050

 tttttgaatt aatctagaaa atgaaaagat ggagttgtat tttgacaaaa 8100

 atgtttgtac tttttaatgt tatttggaat tttaagttct atcagtgact 8150

 tctgaatcct tagaatggcc tctttgtaga accctgtggt atagaggagt 8200

 atggccactg ccccactatt tttattttct tatgtaagtt tgcatatcag 8250

 tcatgactag tgcctagaaa gcaatgtgat ggtcaggatc tcatgacatt 8300

 atatttgagt ttctttcaga tcatttagga tactcttaat ctcacttcat 8350

 caatcaaata ttttttgagt gtatgctgta gctgaaagag tatgtacgta 8400

 cgtataagac tagagagata ttaagtctca gtacacttcc tgtgccatgt 8450

 tattcagctc actggtttac aaatataggt tgtcttgtgg ttgtaggagc 8500

 ccactgtaac aatattgggc agcctttttt tttttttttt aattgcaaca 8550

 atgcaaaagc caagaaagta taagggtcac aagtttaaac aatgaattct 8600

 tcaacaggga aaacagctag cttgaaaact tgctgaaaaa cacaacttgt 8650

 gtttatggca tttagtacct tcaaataatt ggctttgcag atattggata 8700

 ccccattaaa tctgacagtc tcaaattttt catctcttca atcactagtc 8750

 aagaaaaata taaaaacaac aaatacttcc atatggagca tttttcagag 8800

 ttttctaacc cagtcttatt tttctagtca gtaaacattt gtaaaaatac 8850

 tgtttcacta atacttactg ttaactgtct tgagagaaaa gaaaaatatg 8900

 agagaactat tgtttgggga agttcaagtg atctttcaat atcattacta 8950

 acttcttcca ctttttccaa aatttgaata ttaacgctaa aggtgtaaga 9000

 cttcagattt caaattaatc tttctatatt ttttaaattt acagaatatt 9050

 atataaccca ctgctgaaaa agaaaaaaat gattgtttta gaagttaaag 9100

 tcaatattga ttttaaatat aagtaatgaa ggcatatttc caataactag 9150

 tgatatggca tcgttgcaat ttacagtatc ttcaaaaata cagaatttat 9200

 agaataattt ctcctcattt aatatttttc aaaatcaaag ttatggtttc 9250

 ctcattttac taaaatcgta ttctaattct tcattatagt aaatctatga 9300

 gcaactcctt acttcggttc ctctgatttc aaggccatat tttaaaaaat 9350

 caaaaggcac tgtgaactat tttgaagaaa acacgacatt ttaatacaga 9400

 ttgaaaggac ctcttctgaa gctagaaaca atctatagtt atacatcttc 9450

 attaatactg tgttaccttt taaaatagta attttttaca ttttcctgtg 9500

 taaacctaat tgtggtagaa atttttacca actctatact caatcaagca 9550

 aaatttctgt atattccctg tggaatgtac ctatgtgagt ttcagaaatt 9600

 ctcaaaatac gtgttcaaaa atttctgctt ttgcatcttt gggacacctc 9650

 agaaaactta ttaacaactg tgaatatgag aaatacagaa gaaaataata 9700

 agccctctat acataaatgc ccagcacaat tcattgttaa aaaacaacca 9750

 aacctcacac tactgtattt cattatctgt actgaaagca aatgctttgt 9800

 gactattaaa tgttgcacat cattcattca ctgtatagta atcattgact 9850

 aaagccattt gctgtgtttt cttcttgtgg ntgnatatat caggtaaaat 9900

 attttccaaa gagccatgtg tcatgtaata ctgaaccctt tgatattgag 9950

 acattaattt ggacccttgg tattatctac tagaataatg taatactgna 10000

 gaaatattgc tctaattctt tcaaaatggt gcatccccct taaaangttc 10050

 tatttccata aggatttagc ttgcttatcc cttcttatac cctaagatga 10100

 agctgttttt gtgctctttg ttcatcattg gccctcattc caagcacttt 10150

 acgctgtctg taatgggatc tatttttgca ctggaatatc tgagaattgc 10200

 aaaactagac aaaagtttca caacagattt ctaagttaaa tcattttcat 10250

 taaaaggaaa aaagaaaaaa aattttgtat gtcaataact ttatatgaag 10300

 tattaaaatg catatttcta tgttgtaata taatgagtca caaaataaag 10350

 ctgtgacagt tctgttaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 10400

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 10442

<210> 896
<211> 2261
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 9881, 9884, 9999, 10046
<223> Unknown amino acid

<400> 896
 Met Ala Cys Trp Pro Gln Leu Arg Leu Leu Leu Trp Lys Asn Leu
   1               5                  10                  15

 Thr Phe Arg Arg Arg Gln Thr Cys Gln Leu Leu Leu Glu Val Ala
                  20                  25                  30

 Trp Pro Leu Phe Ile Phe Leu Ile Leu Ile Ser Val Arg Leu Ser
                  35                  40                  45

 Tyr Pro Pro Tyr Glu Gln His Glu Cys His Phe Pro Asn Lys Ala
                  50                  55                  60

 Met Pro Ser Ala Gly Thr Leu Pro Trp Val Gln Gly Ile Ile Cys
                  65                  70                  75

 Asn Ala Asn Asn Pro Cys Phe Arg Tyr Pro Thr Pro Gly Glu Ala
                  80                  85                  90

 Pro Gly Val Val Gly Asn Phe Asn Lys Ser Ile Val Ala Arg Leu
                  95                 100                 105

 Phe Ser Asp Ala Arg Arg Leu Leu Leu Tyr Ser Gln Lys Asp Thr
                 110                 115                 120

 Ser Met Lys Asp Met Arg Lys Val Leu Arg Thr Leu Gln Gln Ile
                 125                 130                 135

 Lys Lys Ser Ser Ser Asn Leu Lys Leu Gln Asp Phe Leu Val Asp
                 140                 145                 150

 Asn Glu Thr Phe Ser Gly Phe Leu Tyr His Asn Leu Ser Leu Pro
                 155                 160                 165

 Lys Ser Thr Val Asp Lys Met Leu Arg Ala Asp Val Ile Leu His
                 170                 175                 180

 Lys Val Phe Leu Gln Gly Tyr Gln Leu His Leu Thr Ser Leu Cys
                 185                 190                 195

 Asn Gly Ser Lys Ser Glu Glu Met Ile Gln Leu Gly Asp Gln Glu
                 200                 205                 210

 Val Ser Glu Leu Cys Gly Leu Pro Lys Glu Lys Leu Ala Ala Ala
                 215                 220                 225

 Glu Arg Val Leu Arg Ser Asn Met Asp Ile Leu Lys Pro Ile Leu
                 230                 235                 240

 Arg Thr Leu Asn Ser Thr Ser Pro Phe Pro Ser Lys Glu Leu Ala
                 245                 250                 255

 Glu Ala Thr Lys Thr Leu Leu His Ser Leu Gly Thr Leu Ala Gln
                 260                 265                 270

 Glu Leu Phe Ser Met Arg Ser Trp Ser Asp Met Arg Gln Glu Val
                 275                 280                 285

 Met Phe Leu Thr Asn Val Asn Ser Ser Ser Ser Ser Thr Gln Ile
                 290                 295                 300

 Tyr Gln Ala Val Ser Arg Ile Val Cys Gly His Pro Glu Gly Gly
                 305                 310                 315

 Gly Leu Lys Ile Lys Ser Leu Asn Trp Tyr Glu Asp Asn Asn Tyr
                 320                 325                 330

 Lys Ala Leu Phe Gly Gly Asn Gly Thr Glu Glu Asp Ala Glu Thr
                 335                 340                 345

 Phe Tyr Asp Asn Ser Thr Thr Pro Tyr Cys Asn Asp Leu Met Lys
                 350                 355                 360

 Asn Leu Glu Ser Ser Pro Leu Ser Arg Ile Ile Trp Lys Ala Leu
                 365                 370                 375

 Lys Pro Leu Leu Val Gly Lys Ile Leu Tyr Thr Pro Asp Thr Pro
                 380                 385                 390

 Ala Thr Arg Gln Val Met Ala Glu Val Asn Lys Thr Phe Gln Glu
                 395                 400                 405

 Leu Ala Val Phe His Asp Leu Glu Gly Met Trp Glu Glu Leu Ser
                 410                 415                 420

 Pro Lys Ile Trp Thr Phe Met Glu Asn Ser Gln Glu Met Asp Leu
                 425                 430                 435

 Val Arg Met Leu Leu Asp Ser Arg Asp Asn Asp His Phe Trp Glu
                 440                 445                 450

 Gln Gln Leu Asp Gly Leu Asp Trp Thr Ala Gln Asp Ile Val Ala
                 455                 460                 465

 Phe Leu Ala Lys His Pro Glu Asp Val Gln Ser Ser Asn Gly Ser
                 470                 475                 480

 Val Tyr Thr Trp Arg Glu Ala Phe Asn Glu Thr Asn Gln Ala Ile
                 485                 490                 495

 Arg Thr Ile Ser Arg Phe Met Glu Cys Val Asn Leu Asn Lys Leu
                 500                 505                 510

 Glu Pro Ile Ala Thr Glu Val Trp Leu Ile Asn Lys Ser Met Glu
                 515                 520                 525

 Leu Leu Asp Glu Arg Lys Phe Trp Ala Gly Ile Val Phe Thr Gly
                 530                 535                 540

 Ile Thr Pro Gly Ser Ile Glu Leu Pro His His Val Lys Tyr Lys
                 545                 550                 555

 Ile Arg Met Asp Ile Asp Asn Val Glu Arg Thr Asn Lys Ile Lys
                 560                 565                 570

 Asp Gly Tyr Trp Asp Pro Gly Pro Arg Ala Asp Pro Phe Glu Asp
                 575                 580                 585

 Met Arg Tyr Val Trp Gly Gly Phe Ala Tyr Leu Gln Asp Val Val
                 590                 595                 600

 Glu Gln Ala Ile Ile Arg Val Leu Thr Gly Thr Glu Lys Lys Thr
                 605                 610                 615

 Gly Val Tyr Met Gln Gln Met Pro Tyr Pro Cys Tyr Val Asp Asp
                 620                 625                 630

 Ile Phe Leu Arg Val Met Ser Arg Ser Met Pro Leu Phe Met Thr
                 635                 640                 645

 Leu Ala Trp Ile Tyr Ser Val Ala Val Ile Ile Lys Gly Ile Val
                 650                 655                 660

 Tyr Glu Lys Glu Ala Arg Leu Lys Glu Thr Met Arg Ile Met Gly
                 665                 670                 675

 Leu Asp Asn Ser Ile Leu Trp Phe Ser Trp Phe Ile Ser Ser Leu
                 680                 685                 690

 Ile Pro Leu Leu Val Ser Ala Gly Leu Leu Val Val Ile Leu Lys
                 695                 700                 705

 Leu Gly Asn Leu Leu Pro Tyr Ser Asp Pro Ser Val Val Phe Val
                 710                 715                 720

 Phe Leu Ser Val Phe Ala Val Val Thr Ile Leu Gln Cys Phe Leu
                 725                 730                 735

 Ile Ser Thr Leu Phe Ser Arg Ala Asn Leu Ala Ala Ala Cys Gly
                 740                 745                 750

 Gly Ile Ile Tyr Phe Thr Leu Tyr Leu Pro Tyr Val Leu Cys Val
                 755                 760                 765

 Ala Trp Gln Asp Tyr Val Gly Phe Thr Leu Lys Ile Phe Ala Ser
                 770                 775                 780

 Leu Leu Ser Pro Val Ala Phe Gly Phe Gly Cys Glu Tyr Phe Ala
                 785                 790                 795

 Leu Phe Glu Glu Gln Gly Ile Gly Val Gln Trp Asp Asn Leu Phe
                 800                 805                 810

 Glu Ser Pro Val Glu Glu Asp Gly Phe Asn Leu Thr Thr Ser Ile
                 815                 820                 825

 Ser Met Met Leu Phe Asp Thr Phe Leu Tyr Gly Val Met Thr Trp
                 830                 835                 840

 Tyr Ile Glu Ala Val Phe Pro Gly Gln Tyr Gly Ile Pro Arg Pro
                 845                 850                 855

 Trp Tyr Phe Pro Cys Thr Lys Ser Tyr Trp Phe Gly Glu Glu Ser
                 860                 865                 870

 Asp Glu Lys Ser His Pro Gly Ser Asn Gln Lys Arg Met Ser Glu
                 875                 880                 885

 Ile Cys Met Glu Glu Glu Pro Thr His Leu Lys Leu Gly Val Ser
                 890                 895                 900

 Ile Gln Asn Leu Val Lys Val Tyr Arg Asp Gly Met Lys Val Ala
                 905                 910                 915

 Val Asp Gly Leu Ala Leu Asn Phe Tyr Glu Gly Gln Ile Thr Ser
                 920                 925                 930

 Phe Leu Gly His Asn Gly Ala Gly Lys Thr Thr Thr Met Ser Ile
                 935                 940                 945

 Leu Thr Gly Leu Phe Pro Pro Thr Ser Gly Thr Ala Tyr Ile Leu
                 950                 955                 960

 Gly Lys Asp Ile Arg Ser Glu Met Ser Thr Ile Arg Gln Asn Leu
                 965                 970                 975

 Gly Val Cys Pro Gln His Asn Val Leu Phe Asp Met Leu Thr Val
                 980                 985                 990

 Glu Glu His Ile Trp Phe Tyr Ala Arg Leu Lys Gly Leu Ser Glu
                 995                1000                1005

 Lys His Val Lys Ala Glu Met Glu Gln Met Ala Leu Asp Val Gly
                1010                1015                1020

 Leu Pro Ser Ser Lys Leu Lys Ser Lys Thr Ser Gln Leu Ser Gly
                1025                1030                1035

 Gly Met Gln Arg Lys Leu Ser Val Ala Leu Ala Phe Val Gly Gly
                1040                1045                1050

 Ser Lys Val Val Ile Leu Asp Glu Pro Thr Ala Gly Val Asp Pro
                1055                1060                1065

 Tyr Ser Arg Arg Gly Ile Trp Glu Leu Leu Leu Lys Tyr Arg Gln
                1070                1075                1080

 Gly Arg Thr Ile Ile Leu Ser Thr His His Met Asp Glu Ala Asp
                1085                1090                1095

 Val Leu Gly Asp Arg Ile Ala Ile Ile Ser His Gly Lys Leu Cys
                1100                1105                1110

 Cys Val Gly Ser Ser Leu Phe Leu Lys Asn Gln Leu Gly Thr Gly
                1115                1120                1125

 Tyr Tyr Leu Thr Leu Val Lys Lys Asp Val Glu Ser Ser Leu Ser
                1130                1135                1140

 Ser Cys Arg Asn Ser Ser Ser Thr Val Ser Tyr Leu Lys Lys Glu
                1145                1150                1155

 Asp Ser Val Ser Gln Ser Ser Ser Asp Ala Gly Leu Gly Ser Asp
                1160                1165                1170

 His Glu Ser Asp Thr Leu Thr Ile Asp Val Ser Ala Ile Ser Asn
                1175                1180                1185

 Leu Ile Arg Lys His Val Ser Glu Ala Arg Leu Val Glu Asp Ile
                1190                1195                1200

 Gly His Glu Leu Thr Tyr Val Leu Pro Tyr Glu Ala Ala Lys Glu
                1205                1210                1215

 Gly Ala Phe Val Glu Leu Phe His Glu Ile Asp Asp Arg Leu Ser
                1220                1225                1230

 Asp Leu Gly Ile Ser Ser Tyr Gly Ile Ser Glu Thr Thr Leu Glu
                1235                1240                1245

 Glu Ile Phe Leu Lys Val Ala Glu Glu Ser Gly Val Asp Ala Glu
                1250                1255                1260

 Thr Ser Asp Gly Thr Leu Pro Ala Arg Arg Asn Arg Arg Ala Phe
                1265                1270                1275

 Gly Asp Lys Gln Ser Cys Leu Arg Pro Phe Thr Glu Asp Asp Ala
                1280                1285                1290

 Ala Asp Pro Asn Asp Ser Asp Ile Asp Pro Glu Ser Arg Glu Thr
                1295                1300                1305

 Asp Leu Leu Ser Gly Met Asp Gly Lys Gly Ser Tyr Gln Val Lys
                1310                1315                1320

 Gly Trp Lys Leu Thr Gln Gln Gln Phe Val Ala Leu Leu Trp Lys
                1325                1330                1335

 Arg Leu Leu Ile Ala Arg Arg Ser Arg Lys Gly Phe Phe Ala Gln
                1340                1345                1350

 Ile Val Leu Pro Ala Val Phe Val Cys Ile Ala Leu Val Phe Ser
                1355                1360                1365

 Leu Ile Val Pro Pro Phe Gly Lys Tyr Pro Ser Leu Glu Leu Gln
                1370                1375                1380

 Pro Trp Met Tyr Asn Glu Gln Tyr Thr Phe Val Ser Asn Asp Ala
                1385                1390                1395

 Pro Glu Asp Thr Gly Thr Leu Glu Leu Leu Asn Ala Leu Thr Lys
                1400                1405                1410

 Asp Pro Gly Phe Gly Thr Arg Cys Met Glu Gly Asn Pro Ile Pro
                1415                1420                1425

 Asp Thr Pro Cys Gln Ala Gly Glu Glu Glu Trp Thr Thr Ala Pro
                1430                1435                1440

 Val Pro Gln Thr Ile Met Asp Leu Phe Gln Asn Gly Asn Trp Thr
                1445                1450                1455

 Met Gln Asn Pro Ser Pro Ala Cys Gln Cys Ser Ser Asp Lys Ile
                1460                1465                1470

 Lys Lys Met Leu Pro Val Cys Pro Pro Gly Ala Gly Gly Leu Pro
                1475                1480                1485

 Pro Pro Gln Arg Lys Gln Asn Thr Ala Asp Ile Leu Gln Asp Leu
                1490                1495                1500

 Thr Gly Arg Asn Ile Ser Asp Tyr Leu Val Lys Thr Tyr Val Gln
                1505                1510                1515

 Ile Ile Ala Lys Ser Leu Lys Asn Lys Ile Trp Val Asn Glu Phe
                1520                1525                1530

 Arg Tyr Gly Gly Phe Ser Leu Gly Val Ser Asn Thr Gln Ala Leu
                1535                1540                1545

 Pro Pro Ser Gln Glu Val Asn Asp Ala Ile Lys Gln Met Lys Lys
                1550                1555                1560

 His Leu Lys Leu Ala Lys Asp Ser Ser Ala Asp Arg Phe Leu Asn
                1565                1570                1575

 Ser Leu Gly Arg Phe Met Thr Gly Leu Asp Thr Arg Asn Asn Val
                1580                1585                1590

 Lys Val Trp Phe Asn Asn Lys Gly Trp His Ala Ile Ser Ser Phe
                1595                1600                1605

 Leu Asn Val Ile Asn Asn Ala Ile Leu Arg Ala Asn Leu Gln Lys
                1610                1615                1620

 Gly Glu Asn Pro Ser His Tyr Gly Ile Thr Ala Phe Asn His Pro
                1625                1630                1635

 Leu Asn Leu Thr Lys Gln Gln Leu Ser Glu Val Ala Leu Met Thr
                1640                1645                1650

 Thr Ser Val Asp Val Leu Val Ser Ile Cys Val Ile Phe Ala Met
                1655                1660                1665

 Ser Phe Val Pro Ala Ser Phe Val Val Phe Leu Ile Gln Glu Arg
                1670                1675                1680

 Val Ser Lys Ala Lys His Leu Gln Phe Ile Ser Gly Val Lys Pro
                1685                1690                1695

 Val Ile Tyr Trp Leu Ser Asn Phe Val Trp Asp Met Cys Asn Tyr
                1700                1705                1710

 Val Val Pro Ala Thr Leu Val Ile Ile Ile Phe Ile Cys Phe Gln
                1715                1720                1725

 Gln Lys Ser Tyr Val Ser Ser Thr Asn Leu Pro Val Leu Ala Leu
                1730                1735                1740

 Leu Leu Leu Leu Tyr Gly Trp Ser Ile Thr Pro Leu Met Tyr Pro
                1745                1750                1755

 Ala Ser Phe Val Phe Lys Ile Pro Ser Thr Ala Tyr Val Val Leu
                1760                1765                1770

 Thr Ser Val Asn Leu Phe Ile Gly Ile Asn Gly Ser Val Ala Thr
                1775                1780                1785

 Phe Val Leu Glu Leu Phe Thr Asp Asn Lys Leu Asn Asn Ile Asn
                1790                1795                1800

 Asp Ile Leu Lys Ser Val Phe Leu Ile Phe Pro His Phe Cys Leu
                1805                1810                1815

 Gly Arg Gly Leu Ile Asp Met Val Lys Asn Gln Ala Met Ala Asp
                1820                1825                1830

 Ala Leu Glu Arg Phe Gly Glu Asn Arg Phe Val Ser Pro Leu Ser
                1835                1840                1845

 Trp Asp Leu Val Gly Arg Asn Leu Phe Ala Met Ala Val Glu Gly
                1850                1855                1860

 Val Val Phe Phe Leu Ile Thr Val Leu Ile Gln Tyr Arg Phe Phe
                1865                1870                1875

 Ile Arg Pro Arg Pro Val Asn Ala Lys Leu Ser Pro Leu Asn Asp
                1880                1885                1890

 Glu Asp Glu Asp Val Arg Arg Glu Arg Gln Arg Ile Leu Asp Gly
                1895                1900                1905

 Gly Gly Gln Asn Asp Ile Leu Glu Ile Lys Glu Leu Thr Lys Ile
                1910                1915                1920

 Tyr Arg Arg Lys Arg Lys Pro Ala Val Asp Arg Ile Cys Val Gly
                1925                1930                1935

 Ile Pro Pro Gly Glu Cys Phe Gly Leu Leu Gly Val Asn Gly Ala
                1940                1945                1950

 Gly Lys Ser Ser Thr Phe Lys Met Leu Thr Gly Asp Thr Thr Val
                1955                1960                1965

 Thr Arg Gly Asp Ala Phe Leu Asn Lys Asn Ser Ile Leu Ser Asn
                1970                1975                1980

 Ile His Glu Val His Gln Asn Met Gly Tyr Cys Pro Gln Phe Asp
                1985                1990                1995

 Ala Ile Thr Glu Leu Leu Thr Gly Arg Glu His Val Glu Phe Phe
                2000                2005                2010

 Ala Leu Leu Arg Gly Val Pro Glu Lys Glu Val Gly Lys Val Gly
                2015                2020                2025

 Glu Trp Ala Ile Arg Lys Leu Gly Leu Val Lys Tyr Gly Glu Lys
                2030                2035                2040

 Tyr Ala Gly Asn Tyr Ser Gly Gly Asn Lys Arg Lys Leu Ser Thr
                2045                2050                2055

 Ala Met Ala Leu Ile Gly Gly Pro Pro Val Val Phe Leu Asp Glu
                2060                2065                2070

 Pro Thr Thr Gly Met Asp Pro Lys Ala Arg Arg Phe Leu Trp Asn
                2075                2080                2085

 Cys Ala Leu Ser Val Val Lys Glu Gly Arg Ser Val Val Leu Thr
                2090                2095                2100

 Ser His Ser Met Glu Glu Cys Glu Ala Leu Cys Thr Arg Met Ala
                2105                2110                2115

 Ile Met Val Asn Gly Arg Phe Arg Cys Leu Gly Ser Val Gln His
                2120                2125                2130

 Leu Lys Asn Arg Phe Gly Asp Gly Tyr Thr Ile Val Val Arg Ile
                2135                2140                2145

 Ala Gly Ser Asn Pro Asp Leu Lys Pro Val Gln Asp Phe Phe Gly
                2150                2155                2160

 Leu Ala Phe Pro Gly Ser Val Leu Lys Glu Lys His Arg Asn Met
                2165                2170                2175

 Leu Gln Tyr Gln Leu Pro Ser Ser Leu Ser Ser Leu Ala Arg Ile
                2180                2185                2190

 Phe Ser Ile Leu Ser Gln Ser Lys Lys Arg Leu His Ile Glu Asp
                2195                2200                2205

 Tyr Ser Val Ser Gln Thr Thr Leu Asp Gln Val Phe Val Asn Phe
                2210                2215                2220

 Ala Lys Asp Gln Ser Asp Asp Asp His Leu Lys Asp Leu Ser Leu
                2225                2230                2235

 His Lys Asn Gln Thr Val Val Asp Val Ala Val Leu Thr Ser Phe
                2240                2245                2250

 Leu Gln Asp Glu Lys Val Lys Glu Ser Tyr Val
                2255                2260

<210> 897
<211> 3682
<212> DNA
<213> Homo sapien

<400> 897
 gcgagcgcag cggagcctgg agagaaggcg ctgggctgcg agggcgcgag 50

 ggcgcgaggg cagggggcaa ccggaccccg cccgcaccca tggcgcccgt 100

 cgccgtctgg gccgcgctgg ccgtcggact ggagctctgg gctgcggcgc 150

 acgccttgcc cgcccaggtg gcatttacac cctacgcccc ggagcccggg 200

 agcacatgcc ggctcagaga atactatgac cagacagctc agatgtgctg 250

 cagcaaatgc tcgccgggcc aacatgcaaa agtcttctgt accaagacct 300

 cggacaccgt gtgtgactcc tgtgaggaca gcacatacac ccagctctgg 350

 aactgggttc ccgagtgctt gagctgtggc tcccgctgta gctctgacca 400

 ggtggaaact caagcctgca ctcgggaaca gaaccgcatc tgcacctgca 450

 ggcccggctg gtactgcgcg ctgagcaagc aggaggggtg ccggctgtgc 500

 gcgccgctgc gcaagtgccg cccgggcttc ggcgtggcca gaccaggaac 550

 tgaaacatca gacgtggtgt gcaagccctg tgccccgggg acgttctcca 600

 acacgacttc atccacggat atttgcaggc cccaccagat ctgtaacgtg 650

 gtggccatcc ctgggaatgc aagcatggat gcagtctgca cgtccacgtc 700

 ccccacccgg agtatggccc caggggcagt acacttaccc cagccagtgt 750

 ccacacgatc ccaacacacg cagccaactc cagaacccag cactgctcca 800

 agcacctcct tcctgctccc aatgggcccc agccccccag ctgaagggag 850

 cactggcgac ttcgctcttc cagttggact gattgtgggt gtgacagcct 900

 tgggtctact aataatagga gtggtgaact gtgtcatcat gacccaggtg 950

 aaaaagaagc ccttgtgcct gcagagagaa gccaaggtgc ctcacttgcc 1000

 tgccgataag gcccggggta cacagggccc cgagcagcag cacctgctga 1050

 tcacagcgcc gagctccagc agcagctccc tggagagctc ggccagtgcg 1100

 ttggacagaa gggcgcccac tcggaaccag ccacaggcac caggcgtgga 1150

 ggccagtggg gccggggagg cccgggccag caccgggagc tcagattctt 1200

 cccctggtgg ccatgggacc caggtcaatg tcacctgcat cgtgaacgtc 1250

 tgtagcagct ctgaccacag ctcacagtgc tcctcccaag ccagctccac 1300

 aatgggagac acagattcca gcccctcgga gtccccgaag gacgagcagg 1350

 tccccttctc caaggaggaa tgtgcctttc ggtcacagct ggagacgcca 1400

 gagaccctgc tggggagcac cgaagagaag cccctgcccc ttggagtgcc 1450

 tgatgctggg atgaagccca gttaaccagg ccggtgtggg ctgtgtcgta 1500

 gccaaggtgg gctgagccct ggcaggatga ccctgcgaag gggccctggt 1550

 ccttccaggc ccccaccact aggactctga ggctctttct gggccaagtt 1600

 cctctagtgc cctccacagc cgcagcctcc ctctgacctg caggccaaga 1650

 gcagaggcag cgagttgtgg aaagcctctg ctgccatggc gtgtccctct 1700

 cggaaggctg gctgggcatg gacgttcggg gcatgctggg gcaagtccct 1750

 gactctctgt gacctgcccc gcccagctgc acctgccagc ctggcttctg 1800

 gagcccttgg gttttttgtt tgtttgtttg tttgtttgtt tgtttctccc 1850

 cctgggctct gccccagctc tggcttccag aaaaccccag catccttttc 1900

 tgcagagggg ctttctggag aggagggatg ctgcctgagt cacccatgaa 1950

 gacaggacag tgcttcagcc tgaggctgag actgcgggat ggtcctgggg 2000

 ctctgtgcag ggaggaggtg gcagccctgt agggaacggg gtccttcaag 2050

 ttagctcagg aggcttggaa agcatcacct caggccaggt gcagtggctc 2100

 acgcctatga tcccagcact ttgggaggct gaggcgggtg gatcacctga 2150

 ggttaggagt tcgagaccag cctggccaac atggtaaaac cccatctcta 2200

 ctaaaaatac agaaattagc cgggcgtggt ggcgggcacc tatagtccca 2250

 gctactcaga agcctgaggc tgggaaatcg tttgaacccg ggaagcggag 2300

 gttgcaggga gccgagatca cgccactgca ctccagcctg ggcgacagag 2350

 cgagagtctg tctcaaaaga aaaaaaaaag caccgcctcc aaatgccaac 2400

 ttgtcctttt gtaccatggt gtgaaagtca gatgcccaga gggcccaggc 2450

 aggccaccat attcagtgct gtggcctggg caagataacg cacttctaac 2500

 tagaaatctg ccaatttttt aaaaaagtaa gtaccactca ggccaacaag 2550

 ccaacgacaa agccaaactc tgccagccac atccaacccc ccacctgcca 2600

 tttgcaccct ccgccttcac tccggtgtgc ctgcagcccc gcgcctcctt 2650

 ccttgctgtc ctaggccaca ccatctcctt tcagggaatt tcaggaacta 2700

 gagatgactg agtcctcgta gccatctctc tactcctacc tcagcctaga 2750

 ccctcctcct cccccagagg ggtgggttcc tcttccccac tccccacctt 2800

 caattcctgg gccccaaacg ggctgccctg ccactttggt acatggccag 2850

 tgtgatccca agtgccagtc ttgtgtctgc gtctgtgttg cgtgtcgtgg 2900

 gtgtgtgtag ccaaggtcgg taagttgaat ggcctgcctt gaagccactg 2950

 aagctgggat tcctccccat tagagtcagc cttccccctc ccagggccag 3000

 ggccctgcag aggggaaacc agtgtagcct tgcccggatt ctgggaggaa 3050

 gcaggttgag gggctcctgg aaaggctcag tctcaggagc atggggataa 3100

 aggagaaggc atgaaattgt ctagcagagc aggggcaggg tgataaattg 3150

 ttgataaatt ccactggact tgagcttggc agctgaacta ttggagggtg 3200

 ggagagccca gccattacca tggagacaag aagggttttc caccctggaa 3250

 tcaagatgtc agactggctg gctgcagtga cgtgcacctg tactcaggag 3300

 gctgagggga ggatcactgg agcccaggag tttgaggctg cagcgagcta 3350

 tgatcgcgcc actacactcc agcctgagca acagagtgag accctgtctc 3400

 ttaaagaaaa aaaaagtcag actgctggga ctggccaggt ttctgcccac 3450

 attggaccca catgaggaca tgatggagcg cacctgcccc ctggtggaca 3500

 gtcctgggag aacctcaggc ttccttggca tcacagggca gagccgggaa 3550

 gcgatgaatt tggagactct gtggggcctt ggttcccttg tgtgtgtgtg 3600

 ttgatcccaa gacaatgaaa gtttgcactg tatgctggac ggcattcctg 3650

 cttatcaata aacctgtttg ttttaaaaaa aa 3682

<210> 898
<211> 461
<212> PRT
<213> Homo sapien

<400> 898
 Met Ala Pro Val Ala Val Trp Ala Ala Leu Ala Val Gly Leu Glu
   1               5                  10                  15

 Leu Trp Ala Ala Ala His Ala Leu Pro Ala Gln Val Ala Phe Thr
                  20                  25                  30

 Pro Tyr Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu Tyr
                  35                  40                  45

 Tyr Asp Gln Thr Ala Gln Met Cys Cys Ser Lys Cys Ser Pro Gly
                  50                  55                  60

 Gln His Ala Lys Val Phe Cys Thr Lys Thr Ser Asp Thr Val Cys
                  65                  70                  75

 Asp Ser Cys Glu Asp Ser Thr Tyr Thr Gln Leu Trp Asn Trp Val
                  80                  85                  90

 Pro Glu Cys Leu Ser Cys Gly Ser Arg Cys Ser Ser Asp Gln Val
                  95                 100                 105

 Glu Thr Gln Ala Cys Thr Arg Glu Gln Asn Arg Ile Cys Thr Cys
                 110                 115                 120

 Arg Pro Gly Trp Tyr Cys Ala Leu Ser Lys Gln Glu Gly Cys Arg
                 125                 130                 135

 Leu Cys Ala Pro Leu Arg Lys Cys Arg Pro Gly Phe Gly Val Ala
                 140                 145                 150

 Arg Pro Gly Thr Glu Thr Ser Asp Val Val Cys Lys Pro Cys Ala
                 155                 160                 165

 Pro Gly Thr Phe Ser Asn Thr Thr Ser Ser Thr Asp Ile Cys Arg
                 170                 175                 180

 Pro His Gln Ile Cys Asn Val Val Ala Ile Pro Gly Asn Ala Ser
                 185                 190                 195

 Met Asp Ala Val Cys Thr Ser Thr Ser Pro Thr Arg Ser Met Ala
                 200                 205                 210

 Pro Gly Ala Val His Leu Pro Gln Pro Val Ser Thr Arg Ser Gln
                 215                 220                 225

 His Thr Gln Pro Thr Pro Glu Pro Ser Thr Ala Pro Ser Thr Ser
                 230                 235                 240

 Phe Leu Leu Pro Met Gly Pro Ser Pro Pro Ala Glu Gly Ser Thr
                 245                 250                 255

 Gly Asp Phe Ala Leu Pro Val Gly Leu Ile Val Gly Val Thr Ala
                 260                 265                 270

 Leu Gly Leu Leu Ile Ile Gly Val Val Asn Cys Val Ile Met Thr
                 275                 280                 285

 Gln Val Lys Lys Lys Pro Leu Cys Leu Gln Arg Glu Ala Lys Val
                 290                 295                 300

 Pro His Leu Pro Ala Asp Lys Ala Arg Gly Thr Gln Gly Pro Glu
                 305                 310                 315

 Gln Gln His Leu Leu Ile Thr Ala Pro Ser Ser Ser Ser Ser Ser
                 320                 325                 330

 Leu Glu Ser Ser Ala Ser Ala Leu Asp Arg Arg Ala Pro Thr Arg
                 335                 340                 345

 Asn Gln Pro Gln Ala Pro Gly Val Glu Ala Ser Gly Ala Gly Glu
                 350                 355                 360

 Ala Arg Ala Ser Thr Gly Ser Ser Asp Ser Ser Pro Gly Gly His
                 365                 370                 375

 Gly Thr Gln Val Asn Val Thr Cys Ile Val Asn Val Cys Ser Ser
                 380                 385                 390

 Ser Asp His Ser Ser Gln Cys Ser Ser Gln Ala Ser Ser Thr Met
                 395                 400                 405

 Gly Asp Thr Asp Ser Ser Pro Ser Glu Ser Pro Lys Asp Glu Gln
                 410                 415                 420

 Val Pro Phe Ser Lys Glu Glu Cys Ala Phe Arg Ser Gln Leu Glu
                 425                 430                 435

 Thr Pro Glu Thr Leu Leu Gly Ser Thr Glu Glu Lys Pro Leu Pro
                 440                 445                 450

 Leu Gly Val Pro Asp Ala Gly Met Lys Pro Ser
                 455                 460

<210> 899
<211> 6906
<212> DNA
<213> Homo sapien

<400> 899
 ggcgcgggcg gcctggagcc ccgggagcgg cgcgcgcggt cccggcccag 50

 ccggctctcc tggcctcgcg ctgcacattc tctcctggcg gcggcgccac 100

 ctgcagtagc gttcgcccga acatggcgac acggagcagc aggagggagt 150

 cgcgactccc gttcctattc accctggtcg cactgctgcc gcccggagct 200

 ctctgcgaag tctggacgca gaggctgcac ggcggcagcg cgcccttgcc 250

 ccaggaccgg ggcttcctcg tggtgcaggg cgacccgcgc gagctgcggc 300

 tgtgggcgcg cggggatgcc aggggggcga gccgcgcgga cgagaagccg 350

 ctccggagga aacggagcgc tgccctgcag cccgagccca tcaaggtgta 400

 cggacaggtt agtctgaatg attcccacaa tcagatggtg gtgcactggg 450

 ctggagagaa aagcaacgtg atcgtggcct tggcccgaga tagcctggca 500

 ttggcgaggc ccaagagcag tgatgtgtac gtgtcttacg actatggaaa 550

 atcattcaag aaaatttcag acaagttaaa ctttggcttg ggaaatagga 600

 gtgaagctgt tatcgcccag ttctaccaca gccctgcgga caacaagcgg 650

 tacatctttg cagacgctta tgcccagtac ctctggatca cgtttgactt 700

 ctgcaacact cttcaaggct tttccatccc atttcgggca gctgatctcc 750

 tcctacacag taaggcctcc aaccttctct tgggctttga caggtcccac 800

 cccaacaagc agctgtggaa gtcagatgac tttggccaga cctggatcat 850

 gattcaggaa catgtcaagt ccttttcttg gggaattgat ccctatgaca 900

 aaccaaatac catctacatt gaacgacacg aaccctctgg ctactccact 950

 gtcttccgaa gtacagattt cttccagtcc cgggaaaacc aggaagtgat 1000

 ccttgaggaa gtgagagatt ttcagcttcg ggacaagtac atgtttgcta 1050

 caaaggtggt gcatctcttg ggcagtgaac agcagtcttc tgtccagctc 1100

 tgggtctcct ttggccggaa gcccatgaga gcagcccagt ttgtcacaag 1150

 acatcctatt aatgaatatt acatcgcaga tgcctccgag gaccaggtgt 1200

 ttgtgtgtgt cagccacagt aacaaccgca ccaatttata catctcagag 1250

 gcagaggggc tgaagttctc cctgtccttg gagaacgtgc tctattacag 1300

 cccaggaggg gccggcagtg acaccttggt gaggtatttt gcaaatgaac 1350

 catttgctga cttccaccga gtggaaggat tgcaaggagt ctacattgct 1400

 actctgatta atggttctat gaatgaggag aacatgagat cggtcatcac 1450

 ctttgacaaa gggggaacct gggagtttct tcaggctcca gccttcacgg 1500

 gatatggaga gaaaatcaat tgtgagcttt cccagggctg ttcccttcat 1550

 ctggctcagc gcctcagtca gctcctcaac ctccagctcc ggagaatgcc 1600

 catcctgtcc aaggagtcgg ctccaggcct catcatcgcc actggctcag 1650

 tgggaaagaa cttggctagc aagacaaacg tgtacatctc tagcagtgct 1700

 ggagccaggt ggcgagaggc acttcctgga cctcactact acacatgggg 1750

 agaccacggc ggaatcatca cggccattgc ccagggcatg gaaaccaacg 1800

 agctaaaata cagtaccaat gaaggggaga cctggaaaac attcatcttc 1850

 tctgagaagc cagtgtttgt gtatggcctc ctcacagaac ctggggagaa 1900

 gagcactgtc ttcaccatct ttggctcgaa caaagagaat gtccacagct 1950

 ggctgatcct ccaggtcaat gccacggatg ccttgggagt tccctgcaca 2000

 gagaatgact acaagctgtg gtcaccatct gatgagcggg ggaatgagtg 2050

 tttgctggga cacaagactg ttttcaaacg gcggaccccc catgccacat 2100

 gcttcaatgg agaggacttt gacaggccgg tggtcgtgtc caactgctcc 2150

 tgcacccggg aggactatga gtgtgacttc ggtttcaaga tgagtgaaga 2200

 tttgtcatta gaggtttgtg ttccagatcc ggaattttct ggaaagtcat 2250

 actcccctcc tgtgccttgc cctgtgggtt ctacttacag gagaacgaga 2300

 ggctaccgga agatttctgg ggacacttgt agcggaggag atgttgaagc 2350

 gcgactggaa ggagagctgg tcccctgtcc cctggcagaa gagaacgagt 2400

 tcattctgta tgctgtgagg aaatccatct accgctatga cctggcctcg 2450

 ggagccaccg agcagttgcc tctcaccggg ctacgggcag cagtggccct 2500

 ggactttgac tatgagcaca actgtttgta ttggtccgac ctggccttgg 2550

 acgtcatcca gcgcctctgt ttgaatggaa gcacagggca agaggtgatc 2600

 atcaattctg gcctggagac agtagaagct ttggcttttg aacccctcag 2650

 ccagctgctt tactgggtag atgcaggctt caaaaagatt gaggtagcta 2700

 atccagatgg cgacttccga ctcacaatcg tcaattcctc tgtgcttgat 2750

 cgtcccaggg ctctggtcct cgtgccccaa gagggggtga tgttctggac 2800

 agactgggga gacctgaagc ctgggattta tcggagcaat atggatggtt 2850

 ctgctgccta tcacctggtg tctgaggatg tgaagtggcc caatggcatc 2900

 tctgtggacg accagtggat ttactggacg gatgcctacc tggagtgcat 2950

 agagcggatc acgttcagtg gccagcagcg ctctgtcatt ctggacaacc 3000

 tcccgcaccc ctatgccatt gctgtcttta agaatgaaat ctactgggat 3050

 gactggtcac agctcagcat attccgagct tccaaataca gtgggtccca 3100

 gatggagatt ctggcaaacc agctcacggg gctcatggac atgaagattt 3150

 tctacaaggg gaagaacact ggaagcaatg cctgtgtgcc caggccatgc 3200

 agcctgctgt gcctgcccaa ggccaacaac agtagaagct gcaggtgtcc 3250

 agaggatgtg tccagcagtg tgcttccatc aggggacctg atgtgtgact 3300

 gccctcaggg ctatcagctc aagaacaata cctgtgtcaa agaagagaac 3350

 acctgtcttc gcaaccagta tcgctgcagc aacgggaact gtatcaacag 3400

 catttggtgg tgtgactttg acaacgactg tggagacatg agcgatgaga 3450

 gaaactgccc taccaccatc tgtgacctgg acacccagtt tcgttgccag 3500

 gagtctggga cttgtatccc actgtcctat aaatgtgacc ttgaggatga 3550

 ctgtggagac aacagtgatg aaagtcattg tgaaatgcac cagtgccgga 3600

 gtgacgagta caactgcagt tccggcatgt gcatccgctc ctcctgggta 3650

 tgtgacgggg acaacgactg cagggactgg tctgatgaag ccaactgtac 3700

 cgccatctat cacacctgtg aggcctccaa cttccagtgc cgaaacgggc 3750

 actgcatccc ccagcggtgg gcgtgtgacg gggatacgga ctgccaggat 3800

 ggttccgatg aggatccagt caactgtgag aagaagtgca atggattccg 3850

 ctgcccaaac ggcacttgca tcccatccag caaacattgt gatggtctgc 3900

 gtgattgctc tgatggctcc gatgaacagc actgcgagcc cctctgtacg 3950

 cacttcatgg actttgtgtg taagaaccgc cagcagtgcc tgttccactc 4000

 catggtctgt gacggaatca tccagtgccg cgacgggtcc gatgaggatg 4050

 cggcgtttgc aggatgctcc caagatcctg agttccacaa ggtatgtgat 4100

 gagttcggtt tccagtgtca gaatggagtg tgcatcagtt tgatttggaa 4150

 gtgcgacggg atggatgatt gcggcgatta ttctgatgaa gccaactgcg 4200

 aaaaccccac agaagcccca aactgctccc gctacttcca gtttcggtgt 4250

 gagaatggcc actgcatccc caacagatgg aaatgtgaca gggagaacga 4300

 ctgtggggac tggtctgatg agaaggattg tggagattca catattcttc 4350

 ccttctcgac tcctgggccc tccacgtgtc tgcccaatta ctaccgctgc 4400

 agcagtggga cctgcgtgat ggacacctgg gtgtgcgacg ggtaccgaga 4450

 ttgtgcagat ggctctgacg aggaagcctg ccccttgctt gcaaacgtca 4500

 ctgctgcctc cactcccacc caacttgggc gatgtgaccg atttgagttc 4550

 gaatgccacc aaccgaagac gtgtattccc aactggaagc gctgtgacgg 4600

 ccaccaagat tgccaggatg gccgggacga ggccaattgc cccacacaca 4650

 gcaccttgac ttgcatgagc agggagttcc agtgcgagga cggggaggcc 4700

 tgcattgtgc tctcggagcg ctgcgacggc ttcctggact gctcggacga 4750

 gagcgatgaa aaggcctgca gtgatgagtt gactgtgtac aaagtacaga 4800

 atcttcagtg gacagctgac ttctctgggg atgtgacttt gacctggatg 4850

 aggcccaaaa aaatgccctc tgcttcttgt gtatataatg tctactacag 4900

 ggtggttgga gagagcatat ggaagactct ggagacccac agcaataaga 4950

 caaacactgt attaaaagtc ttgaaaccag ataccacgta tcaggttaaa 5000

 gtacaggttc agtgtctcag caaggcacac aacaccaatg actttgtgac 5050

 cctgaggacc ccagagggat tgccagatgc ccctcgaaat ctccagctgt 5100

 cactccccag ggaagcagaa ggtgtgattg taggccactg ggctcctccc 5150

 atccacaccc atggcctcat ccgtgagtac attgtagaat acagcaggag 5200

 tggttccaag atgtgggcct cccagagggc tgctagtaac tttacagaaa 5250

 tcaagaactt attggtcaac actctataca ccgtcagagt ggctgcggtg 5300

 actagtcgtg gaataggaaa ctggagcgat tctaaatcca ttaccaccat 5350

 aaaaggaaaa gtgatcccac caccagatat ccacattgac agctatggtg 5400

 aaaattatct aagcttcacc ctgaccatgg agagtgatat caaggtgaat 5450

 ggctatgtgg tgaacctttt ctgggcattt gacacccaca agcaagagag 5500

 gagaactttg aacttccgag gaagcatatt gtcacacaaa gttggcaatc 5550

 tgacagctca tacatcctat gagatttctg cctgggccaa gactgacttg 5600

 ggggatagcc ctctggcatt tgagcatgtt atgaccagag gggttcgccc 5650

 acctgcacct agcctcaagg ccaaagccat caaccagact gcagtggaat 5700

 gtacctggac cggcccccgg aatgtggttt atggtatttt ctatgccacg 5750

 tcctttcttg acctctatcg caacccgaag agcttgacta cttcactcca 5800

 caacaagacg gtcattgtca gtaaggatga gcagtatttg tttctggtcc 5850

 gtgtagtggt accctaccag gggccatcct ctgactacgt tgtagtgaag 5900

 atgatcccgg acagcaggct tccaccccgt cacctgcatg tggttcatac 5950

 gggcaaaacc tccgtggtca tcaagtggga atcaccgtat gactctcctg 6000

 accaggactt gttgtatgca attgcagtca aagatctcat aagaaagact 6050

 gacaggagct acaaagtaaa atcccgtaac agcactgtgg aatacaccct 6100

 taacaagttg gagcctggcg ggaaatacca catcattgtc caactgggga 6150

 acatgagcaa agattccagc ataaaaatta ccacagtttc attatcagca 6200

 cctgatgcct taaaaatcat aacagaaaat gatcatgttc ttctgttttg 6250

 gaaaagcctg gctttaaagg aaaagcattt taatgaaagc aggggctatg 6300

 agatacacat gtttgatagt gccatgaata tcacagctta ccttgggaat 6350

 actactgaca atttctttaa aatttccaac ctgaagatgg gtcataatta 6400

 cacgttcacc gtccaagcaa gatgcctttt tggcaaccag atctgtgggg 6450

 agcctgccat cctgctgtac gatgagctgg ggtctggtgc agatgcatct 6500

 gcaacgcagg ctgccagatc tacggatgtt gctgctgtgg tggtgcccat 6550

 cttattcctg atactgctga gcctgggggt ggggtttgcc atcctgtaca 6600

 cgaagcaccg gaggctgcag agcagcttca ccgccttcgc caacagccac 6650

 tacagctcca ggctggggtc cgcaatcttc tcctctgggg atgacctggg 6700

 ggaagatgat gaagatgccc ctatgataac tggattttca gatgacgtcc 6750

 ccatggtgat agcctgaaag agctttcctc actagaaacc aaatggtgta 6800

 aatattttat ttgataaaga tagttgatgg tttattttaa aagatgcact 6850

 ttgagttgca atatgttatt tttatatggg ccaaaaacaa aaaacaaaaa 6900

 aaaaaa 6906

<210> 900
<211> 2000
<212> PRT
<213> Homo sapien

<400> 900
 Met Ala Thr Arg Ser Ser Arg Arg Glu Ser Arg Leu Pro Phe Leu
   1               5                  10                  15

 Phe Thr Leu Val Ala Leu Leu Pro Pro Gly Ala Leu Cys Glu Val
                  20                  25                  30

 Trp Thr Gln Arg Leu His Gly Gly Ser Ala Pro Leu Pro Gln Asp
                  35                  40                  45

 Arg Gly Phe Leu Val Val Gln Gly Asp Pro Arg Glu Leu Arg Leu
                  50                  55                  60

 Trp Ala Arg Gly Asp Ala Arg Gly Ala Ser Arg Ala Asp Glu Lys
                  65                  70                  75

 Pro Leu Arg Arg Lys Arg Ser Ala Ala Leu Gln Pro Glu Pro Ile
                  80                  85                  90

 Lys Val Tyr Gly Gln Val Ser Leu Asn Asp Ser His Asn Gln Met
                  95                 100                 105

 Val Val His Trp Ala Gly Glu Lys Ser Asn Val Ile Val Ala Leu
                 110                 115                 120

 Ala Arg Asp Ser Leu Ala Leu Ala Arg Pro Lys Ser Ser Asp Val
                 125                 130                 135

 Tyr Val Ser Tyr Asp Tyr Gly Lys Ser Phe Lys Lys Ile Ser Asp
                 140                 145                 150

 Lys Leu Asn Phe Gly Leu Gly Asn Arg Ser Glu Ala Val Ile Ala
                 155                 160                 165

 Gln Phe Tyr His Ser Pro Ala Asp Asn Lys Arg Tyr Ile Phe Ala
                 170                 175                 180

 Asp Ala Tyr Ala Gln Tyr Leu Trp Ile Thr Phe Asp Phe Cys Asn
                 185                 190                 195

 Thr Leu Gln Gly Phe Ser Ile Pro Phe Arg Ala Ala Asp Leu Leu
                 200                 205                 210

 Leu His Ser Lys Ala Ser Asn Leu Leu Leu Gly Phe Asp Arg Ser
                 215                 220                 225

 His Pro Asn Lys Gln Leu Trp Lys Ser Asp Asp Phe Gly Gln Thr
                 230                 235                 240

 Trp Ile Met Ile Gln Glu His Val Lys Ser Phe Ser Trp Gly Ile
                 245                 250                 255

 Asp Pro Tyr Asp Lys Pro Asn Thr Ile Tyr Ile Glu Arg His Glu
                 260                 265                 270

 Pro Ser Gly Tyr Ser Thr Val Phe Arg Ser Thr Asp Phe Phe Gln
                 275                 280                 285

 Ser Arg Glu Asn Gln Glu Val Ile Leu Glu Glu Val Arg Asp Phe
                 290                 295                 300

 Gln Leu Arg Asp Lys Tyr Met Phe Ala Thr Lys Val Val His Leu
                 305                 310                 315

 Leu Gly Ser Glu Gln Gln Ser Ser Val Gln Leu Trp Val Ser Phe
                 320                 325                 330

 Gly Arg Lys Pro Met Arg Ala Ala Gln Phe Val Thr Arg His Pro
                 335                 340                 345

 Ile Asn Glu Tyr Tyr Ile Ala Asp Ala Ser Glu Asp Gln Val Phe
                 350                 355                 360

 Val Cys Val Ser His Ser Asn Asn Arg Thr Asn Leu Tyr Ile Ser
                 365                 370                 375

 Glu Ala Glu Gly Leu Lys Phe Ser Leu Ser Leu Glu Asn Val Leu
                 380                 385                 390

 Tyr Tyr Ser Pro Gly Gly Ala Gly Ser Asp Thr Leu Val Arg Tyr
                 395                 400                 405

 Phe Ala Asn Glu Pro Phe Ala Asp Phe His Arg Val Glu Gly Leu
                 410                 415                 420

 Gln Gly Val Tyr Ile Ala Thr Leu Ile Asn Gly Ser Met Asn Glu
                 425                 430                 435

 Glu Asn Met Arg Ser Val Ile Thr Phe Asp Lys Gly Gly Thr Trp
                 440                 445                 450

 Glu Phe Leu Gln Ala Pro Ala Phe Thr Gly Tyr Gly Glu Lys Ile
                 455                 460                 465

 Asn Cys Glu Leu Ser Gln Gly Cys Ser Leu His Leu Ala Gln Arg
                 470                 475                 480

 Leu Ser Gln Leu Leu Asn Leu Gln Leu Arg Arg Met Pro Ile Leu
                 485                 490                 495

 Ser Lys Glu Ser Ala Pro Gly Leu Ile Ile Ala Thr Gly Ser Val
                 500                 505                 510

 Gly Lys Asn Leu Ala Ser Lys Thr Asn Val Tyr Ile Ser Ser Ser
                 515                 520                 525

 Ala Gly Ala Arg Trp Arg Glu Ala Leu Pro Gly Pro His Tyr Tyr
                 530                 535                 540

 Thr Trp Gly Asp His Gly Gly Ile Ile Thr Ala Ile Ala Gln Gly
                 545                 550                 555

 Met Glu Thr Asn Glu Leu Lys Tyr Ser Thr Asn Glu Gly Glu Thr
                 560                 565                 570

 Trp Lys Thr Phe Ile Phe Ser Glu Lys Pro Val Phe Val Tyr Gly
                 575                 580                 585

 Leu Leu Thr Glu Pro Gly Glu Lys Ser Thr Val Phe Thr Ile Phe
                 590                 595                 600

 Gly Ser Asn Lys Glu Asn Val His Ser Trp Leu Ile Leu Gln Val
                 605                 610                 615

 Asn Ala Thr Asp Ala Leu Gly Val Pro Cys Thr Glu Asn Asp Tyr
                 620                 625                 630

 Lys Leu Trp Ser Pro Ser Asp Glu Arg Gly Asn Glu Cys Leu Leu
                 635                 640                 645

 Gly His Lys Thr Val Phe Lys Arg Arg Thr Pro His Ala Thr Cys
                 650                 655                 660

 Phe Asn Gly Glu Asp Phe Asp Arg Pro Val Val Val Ser Asn Cys
                 665                 670                 675

 Ser Cys Thr Arg Glu Asp Tyr Glu Cys Asp Phe Gly Phe Lys Met
                 680                 685                 690

 Ser Glu Asp Leu Ser Leu Glu Val Cys Val Pro Asp Pro Glu Phe
                 695                 700                 705

 Ser Gly Lys Ser Tyr Ser Pro Pro Val Pro Cys Pro Val Gly Ser
                 710                 715                 720

 Thr Tyr Arg Arg Thr Arg Gly Tyr Arg Lys Ile Ser Gly Asp Thr
                 725                 730                 735

 Cys Ser Gly Gly Asp Val Glu Ala Arg Leu Glu Gly Glu Leu Val
                 740                 745                 750

 Pro Cys Pro Leu Ala Glu Glu Asn Glu Phe Ile Leu Tyr Ala Val
                 755                 760                 765

 Arg Lys Ser Ile Tyr Arg Tyr Asp Leu Ala Ser Gly Ala Thr Glu
                 770                 775                 780

 Gln Leu Pro Leu Thr Gly Leu Arg Ala Ala Val Ala Leu Asp Phe
                 785                 790                 795

 Asp Tyr Glu His Asn Cys Leu Tyr Trp Ser Asp Leu Ala Leu Asp
                 800                 805                 810

 Val Ile Gln Arg Leu Cys Leu Asn Gly Ser Thr Gly Gln Glu Val
                 815                 820                 825

 Ile Ile Asn Ser Gly Leu Glu Thr Val Glu Ala Leu Ala Phe Glu
                 830                 835                 840

 Pro Leu Ser Gln Leu Leu Tyr Trp Val Asp Ala Gly Phe Lys Lys
                 845                 850                 855

 Ile Glu Val Ala Asn Pro Asp Gly Asp Phe Arg Leu Thr Ile Val
                 860                 865                 870

 Asn Ser Ser Val Leu Asp Arg Pro Arg Ala Leu Val Leu Val Pro
                 875                 880                 885

 Gln Glu Gly Val Met Phe Trp Thr Asp Trp Gly Asp Leu Lys Pro
                 890                 895                 900

 Gly Ile Tyr Arg Ser Asn Met Asp Gly Ser Ala Ala Tyr His Leu
                 905                 910                 915

 Val Ser Glu Asp Val Lys Trp Pro Asn Gly Ile Ser Val Asp Asp
                 920                 925                 930

 Gln Trp Ile Tyr Trp Thr Asp Ala Tyr Leu Glu Cys Ile Glu Arg
                 935                 940                 945

 Ile Thr Phe Ser Gly Gln Gln Arg Ser Val Ile Leu Asp Asn Leu
                 950                 955                 960

 Pro His Pro Tyr Ala Ile Ala Val Phe Lys Asn Glu Ile Tyr Trp
                 965                 970                 975

 Asp Asp Trp Ser Gln Leu Ser Ile Phe Arg Ala Ser Lys Tyr Ser
                 980                 985                 990

 Gly Ser Gln Met Glu Ile Leu Ala Asn Gln Leu Thr Gly Leu Met
                 995                1000                1005

 Asp Met Lys Ile Phe Tyr Lys Gly Lys Asn Thr Gly Ser Asn Ala
                1010                1015                1020

 Cys Val Pro Arg Pro Cys Ser Leu Leu Cys Leu Pro Lys Ala Asn
                1025                1030                1035

 Asn Ser Arg Ser Cys Arg Cys Pro Glu Asp Val Ser Ser Ser Val
                1040                1045                1050

 Leu Pro Ser Gly Asp Leu Met Cys Asp Cys Pro Gln Gly Tyr Gln
                1055                1060                1065

 Leu Lys Asn Asn Thr Cys Val Lys Glu Glu Asn Thr Cys Leu Arg
                1070                1075                1080

 Asn Gln Tyr Arg Cys Ser Asn Gly Asn Cys Ile Asn Ser Ile Trp
                1085                1090                1095

 Trp Cys Asp Phe Asp Asn Asp Cys Gly Asp Met Ser Asp Glu Arg
                1100                1105                1110

 Asn Cys Pro Thr Thr Ile Cys Asp Leu Asp Thr Gln Phe Arg Cys
                1115                1120                1125

 Gln Glu Ser Gly Thr Cys Ile Pro Leu Ser Tyr Lys Cys Asp Leu
                1130                1135                1140

 Glu Asp Asp Cys Gly Asp Asn Ser Asp Glu Ser His Cys Glu Met
                1145                1150                1155

 His Gln Cys Arg Ser Asp Glu Tyr Asn Cys Ser Ser Gly Met Cys
                1160                1165                1170

 Ile Arg Ser Ser Trp Val Cys Asp Gly Asp Asn Asp Cys Arg Asp
                1175                1180                1185

 Trp Ser Asp Glu Ala Asn Cys Thr Ala Ile Tyr His Thr Cys Glu
                1190                1195                1200

 Ala Ser Asn Phe Gln Cys Arg Asn Gly His Cys Ile Pro Gln Arg
                1205                1210                1215

 Trp Ala Cys Asp Gly Asp Thr Asp Cys Gln Asp Gly Ser Asp Glu
                1220                1225                1230

 Asp Pro Val Asn Cys Glu Lys Lys Cys Asn Gly Phe Arg Cys Pro
                1235                1240                1245

 Asn Gly Thr Cys Ile Pro Ser Ser Lys His Cys Asp Gly Leu Arg
                1250                1255                1260

 Asp Cys Ser Asp Gly Ser Asp Glu Gln His Cys Glu Pro Leu Cys
                1265                1270                1275

 Thr His Phe Met Asp Phe Val Cys Lys Asn Arg Gln Gln Cys Leu
                1280                1285                1290

 Phe His Ser Met Val Cys Asp Gly Ile Ile Gln Cys Arg Asp Gly
                1295                1300                1305

 Ser Asp Glu Asp Ala Ala Phe Ala Gly Cys Ser Gln Asp Pro Glu
                1310                1315                1320

 Phe His Lys Val Cys Asp Glu Phe Gly Phe Gln Cys Gln Asn Gly
                1325                1330                1335

 Val Cys Ile Ser Leu Ile Trp Lys Cys Asp Gly Met Asp Asp Cys
                1340                1345                1350

 Gly Asp Tyr Ser Asp Glu Ala Asn Cys Glu Asn Pro Thr Glu Ala
                1355                1360                1365

 Pro Asn Cys Ser Arg Tyr Phe Gln Phe Arg Cys Glu Asn Gly His
                1370                1375                1380

 Cys Ile Pro Asn Arg Trp Lys Cys Asp Arg Glu Asn Asp Cys Gly
                1385                1390                1395

 Asp Trp Ser Asp Glu Lys Asp Cys Gly Asp Ser His Ile Leu Pro
                1400                1405                1410

 Phe Ser Thr Pro Gly Pro Ser Thr Cys Leu Pro Asn Tyr Tyr Arg
                1415                1420                1425

 Cys Ser Ser Gly Thr Cys Val Met Asp Thr Trp Val Cys Asp Gly
                1430                1435                1440

 Tyr Arg Asp Cys Ala Asp Gly Ser Asp Glu Glu Ala Cys Pro Leu
                1445                1450                1455

 Leu Ala Asn Val Thr Ala Ala Ser Thr Pro Thr Gln Leu Gly Arg
                1460                1465                1470

 Cys Asp Arg Phe Glu Phe Glu Cys His Gln Pro Lys Thr Cys Ile
                1475                1480                1485

 Pro Asn Trp Lys Arg Cys Asp Gly His Gln Asp Cys Gln Asp Gly
                1490                1495                1500

 Arg Asp Glu Ala Asn Cys Pro Thr His Ser Thr Leu Thr Cys Met
                1505                1510                1515

 Ser Arg Glu Phe Gln Cys Glu Asp Gly Glu Ala Cys Ile Val Leu
                1520                1525                1530

 Ser Glu Arg Cys Asp Gly Phe Leu Asp Cys Ser Asp Glu Ser Asp
                1535                1540                1545

 Glu Lys Ala Cys Ser Asp Glu Leu Thr Val Tyr Lys Val Gln Asn
                1550                1555                1560

 Leu Gln Trp Thr Ala Asp Phe Ser Gly Asp Val Thr Leu Thr Trp
                1565                1570                1575

 Met Arg Pro Lys Lys Met Pro Ser Ala Ser Cys Val Tyr Asn Val
                1580                1585                1590

 Tyr Tyr Arg Val Val Gly Glu Ser Ile Trp Lys Thr Leu Glu Thr
                1595                1600                1605

 His Ser Asn Lys Thr Asn Thr Val Leu Lys Val Leu Lys Pro Asp
                1610                1615                1620

 Thr Thr Tyr Gln Val Lys Val Gln Val Gln Cys Leu Ser Lys Ala
                1625                1630                1635

 His Asn Thr Asn Asp Phe Val Thr Leu Arg Thr Pro Glu Gly Leu
                1640                1645                1650

 Pro Asp Ala Pro Arg Asn Leu Gln Leu Ser Leu Pro Arg Glu Ala
                1655                1660                1665

 Glu Gly Val Ile Val Gly His Trp Ala Pro Pro Ile His Thr His
                1670                1675                1680

 Gly Leu Ile Arg Glu Tyr Ile Val Glu Tyr Ser Arg Ser Gly Ser
                1685                1690                1695

 Lys Met Trp Ala Ser Gln Arg Ala Ala Ser Asn Phe Thr Glu Ile
                1700                1705                1710

 Lys Asn Leu Leu Val Asn Thr Leu Tyr Thr Val Arg Val Ala Ala
                1715                1720                1725

 Val Thr Ser Arg Gly Ile Gly Asn Trp Ser Asp Ser Lys Ser Ile
                1730                1735                1740

 Thr Thr Ile Lys Gly Lys Val Ile Pro Pro Pro Asp Ile His Ile
                1745                1750                1755

 Asp Ser Tyr Gly Glu Asn Tyr Leu Ser Phe Thr Leu Thr Met Glu
                1760                1765                1770

 Ser Asp Ile Lys Val Asn Gly Tyr Val Val Asn Leu Phe Trp Ala
                1775                1780                1785

 Phe Asp Thr His Lys Gln Glu Arg Arg Thr Leu Asn Phe Arg Gly
                1790                1795                1800

 Ser Ile Leu Ser His Lys Val Gly Asn Leu Thr Ala His Thr Ser
                1805                1810                1815

 Tyr Glu Ile Ser Ala Trp Ala Lys Thr Asp Leu Gly Asp Ser Pro
                1820                1825                1830

 Leu Ala Phe Glu His Val Met Thr Arg Gly Val Arg Pro Pro Ala
                1835                1840                1845

 Pro Ser Leu Lys Ala Lys Ala Ile Asn Gln Thr Ala Val Glu Cys
                1850                1855                1860

 Thr Trp Thr Gly Pro Arg Asn Val Val Tyr Gly Ile Phe Tyr Ala
                1865                1870                1875

 Thr Ser Phe Leu Asp Leu Tyr Arg Asn Pro Lys Ser Leu Thr Thr
                1880                1885                1890

 Ser Leu His Asn Lys Thr Val Ile Val Ser Lys Asp Glu Gln Tyr
                1895                1900                1905

 Leu Phe Leu Val Arg Val Val Val Pro Tyr Gln Gly Pro Ser Ser
                1910                1915                1920

 Asp Tyr Val Val Val Lys Met Ile Pro Asp Ser Arg Leu Pro Pro
                1925                1930                1935

 Arg His Leu His Val Val His Thr Gly Lys Thr Ser Val Val Ile
                1940                1945                1950

 Lys Trp Glu Ser Pro Tyr Asp Ser Pro Asp Gln Asp Leu Leu Tyr
                1955                1960                1965

 Ala Ile Ala Val Lys Asp Leu Ile Arg Lys Thr Asp Arg Ser Tyr
                1970                1975                1980

 Lys Val Lys Ser Arg Asn Ser Thr Val Glu Tyr Thr Leu Asn Lys
                1985                1990                1995

 Leu Glu Pro Gly Gly
                2000

<210> 901
<211> 1292
<212> DNA
<213> Homo sapien

<400> 901
 taaaaaccca ctgtttgaga atgatgctac tctgatctaa tgaatgtgaa 50

 cgtgtagatg ttttgtgtgt atttttttaa atgaaaactc aaaataagac 100

 aagtaatttg ttgataaata tttttaaaga taactcagca tgtttgtaaa 150

 gcaggataca ttttactaaa aggttcattg gttccaatca cagctcatag 200

 gtagagcaaa gaaagggtgg atggattgaa aagattagcc tctgtctcgg 250

 tggcaggttc ccacctcgca agcaattgga aacaaaactt ttggggagtt 300

 ttattttgca ttagggtgtg ttttatgtta agcaaaacat actttagaag 350

 caaatgaaaa aggcaattga aaatcccagc tatttcacct agatggaata 400

 gccaccctga gcagaacttt gtgatgcttc attctgtgga attttgtgct 450

 tactactgta tagtgcatgt ggtgtaggtt actctaactg gttttgtcga 500

 cgtaaacatt taaagtgtta tattttttat aaaaatgttt atttttaatg 550

 atatgagaaa aattttgtta ggccacaaaa acactgcact gtgaacattt 600

 tagaaaaggt atgtcagact gggattaatg acagcatgat tttcaatgac 650

 tgtaaattgc gataaggaaa tgtactgatt gccaatacac cccaccctca 700

 ttacatcatc aggacttgaa gccaagggtt aacccagcaa gctacaaaga 750

 gggtgtgtca cactgaaact caatagttga gtttggctgt tgttgcagga 800

 aaatgattat aactaaaagc tctctgatag tgcagagact taccagaaga 850

 cacaaggaat tgtactgaag agctattaca atccaaatat tgccgtttca 900

 taaatgtaat aagtaatact aattcacaga gtattgtaaa tggtggatga 950

 caaaagaaaa tctgctctgt ggaaagaaag aactgtctct accagggtca 1000

 agagcatgaa cgcatcaata gaaagaactc ggggaaacat cccatcaaca 1050

 ggactacaca cttgtatata cattcttgag aacactgcaa tgtgaaaatc 1100

 acgtttgcta tttataaact tgtccttaga ttaatgtgtc tggacagatt 1150

 gtgggagtaa gtgattcttc taagaattag atacttgtca ctgcctatac 1200

 ctgcagctga actgaatggt acttcgtatg ttaatagttg ttctgataaa 1250

 tcatgcaatt aaagtaaagt gatgcaacat cttgtatact ga 1292

<210> 902
<211> 6
<212> PRT
<213> Homo sapien

<400> 902
 Met Gln His Leu Val Tyr
   1               5

<210> 903
<211> 7752
<212> DNA
<213> Homo sapien

<400> 903
 gatggctgca gaggaagggg tcgcgagtgc tgcttccgcc ggcggtagct 50

 ggggcaccgc ggccatgggg cgggttctac cgatgctgtt ggtgccagtc 100

 cccgccgagg cgatggggca gctcggctcc cgggcgcagc tgcgcacaca 150

 gccggaggct ctggggagcc tgacggctgc gggcagcctc caagtgcttt 200

 ctttgacgcc tggcagccgg ggcgggggtc gctgctgcct ggagggcccc 250

 ttctggcact ttctatggga ggattctcgt aacagcagca caccaactga 300

 aaagcccaaa ctgctcgctc ttggtgaaaa ttatgaactg cttatctatg 350

 aatttaattt gaaagatgga agatgtgatg caaccatttt gtatagctgt 400

 agtagggagg cattgcaaaa gctcattgac gatcaagata tcagtatttc 450

 cttattgtct ttgagaatcc tgtcatttca caataacaca tcattactgt 500

 tcatcaacaa atgtgtcatc ctacatatta tatttcctga aagagatgct 550

 gcaattagag tactcaactg tttcacactt cccttgcctg cacaggcagt 600

 ggacatgatt attgacacgc agctctgcag aggaattctt tttgttttga 650

 gtagtttagg ctggatctac atttttgatg ttgtggatgg tacatatgta 700

 gctcatgtgg atttagcact tcacaaagaa gacatgtgta atgagcagca 750

 acaggagcca gccaagattt cttcatttac ttcactgaaa gtttctcaag 800

 acctcgatgt tgcagtgatt gtcagctcct ccaactccgc agttgctctt 850

 aacttaaatt tgtatttcag gcaacaccca ggacacctac tgtgtgaaag 900

 aatactagaa gatcttccta ttcaaggacc taagggcgta gatgaagatg 950

 atcctgttaa ctctgcctac aacatgaaac tggccaagtt ttccttccaa 1000

 attgataggt cttggaaagc ccagctatca tcattgaatg aaacaataaa 1050

 gaactccaaa ctggaggttt cctgttgtgc tccatggttc caggatattt 1100

 tgcatttgga gtcacctgaa tctggtaacc acagtacaag tgtgcagagc 1150

 tgggccttca ttccacagga cataatgcat gggcaatata atgttctaca 1200

 gaaagatcat gccaagacca gtgatccagg aagatcatgg aaaataatgc 1250

 acatcagtga acaagaggaa cccatagagc ttaaatgtgt gtctgtgaca 1300

 ggattcactg cactgtttac ttgggaagtg gaaaggatgg gctataccat 1350

 taccctctgg gatttggaga cccagggcat gcagtgttct tcccttggca 1400

 caaagtgtat tcctgtagac agtagtggag accagcagct gtgctttgtt 1450

 ttgacagaga atggactctc tctgattttg tttggtttga ctcaagaaga 1500

 gtttttaaac agactcatga tccatggaag tgccagcact gtggacactc 1550

 tttgtcatct caatggctgg ggaaggtgct caattcccat acatgcacta 1600

 gaggccggga tagaaaatcg tcagctggac acagtaaatt tctttttgaa 1650

 gagcaaggaa aatcttttta atccatcctc aaaatcttct gtatctgatc 1700

 agtttgatca cttgtcatcc catttatatt taagaaatgt ggaagagctg 1750

 ataccagcat tggatttact ttgctcggca attagagaaa gttattctga 1800

 accccaaagc aaacactttt cagaacaatt gcttaatctt acactgtctt 1850

 tccttaacaa ccaaataaag gagcttttca ttcacactga agaactagat 1900

 gaacatctgc aaaaaggagt gaacattttg actagctaca ttaatgaact 1950

 tcgaaccttc atgataaagt ttccttggaa gctaacagat gctatagatg 2000

 aatatgatgt acatgaaaat gtccccaaag taaaggagag caatatatgg 2050

 aagaaactca gctttgagga agttattgcc agcgccattt taaacaacaa 2100

 aataccagag gcacagactt tcttcaggat tgatagtcat tctgctcaaa 2150

 aacttgagga gcttattggc ataggcctaa atttggtctt tgacaattta 2200

 aaaaagaaca atataaagga agcctctgaa cttttgaaga atatggggtt 2250

 tgatgtaaaa ggccaattgc tcaagatctg cttctataca actaataaaa 2300

 atatacgtga ctttttggtt gaaattttaa aagaaaaaaa ttatttttct 2350

 gaaaaagaga aaagaactat agacttcgtg catcaagttg agaagcttta 2400

 tttgggacat ttccaagaaa atatgcaaat ccagtcattt cccaggtact 2450

 ggataaagga acaagatttt ttcaagcaca agtctgtttt ggactcattc 2500

 ctgaaatatg attgtaaaga tgaatttaac aaacaggacc atagaattgt 2550

 gttaaattgg gctctgtggt gggatcaact aacacaagaa tccatccttc 2600

 tccccaggat aagtccagaa gaatacaaat catattcccc tgaagccctc 2650

 tggagatacc tcacagctcg ccatgattgg ttaaacatta tcttatggat 2700

 tggagaattt caaacccagc atagttatgc ttcacttcag cagaacaaat 2750

 ggccccttct gactgttgat gttattaacc agaatacttc ctgtaacaac 2800

 tacatgagga atgaaatttt agataagctg gccaggaatg gggttttttt 2850

 ggcatctgaa ctggaagact ttgaatgctt cctcctaaga ctgagccgta 2900

 ttggaggtgt aatacaggat accctccctg ttcaaaacta caagaccaaa 2950

 gaaggttggg atttccattc tcaattcatt ctctattgtt tggagcacag 3000

 tctgcagcat cttctttatg tctaccttga ctgttacaaa cttagtcctg 3050

 aaaattgtcc ctttttggaa aaaaaagagt tacatgaagc acacccttgg 3100

 tttgaatttt tagttcagtg tcgacaagtt gccagtaact taacagatcc 3150

 caaactgatc ttccaggcta gccttgcaaa tgctcagatt ttgattccca 3200

 ccaatcaggc cagtgtaagc agtatgctat tggaaggaca taccctcctg 3250

 gcccttgcta ctacaatgta ttctcctggg ggtgtcagtc aggttgttca 3300

 gaatgaagaa aatgaaaact gtttgaagaa agtggatccc cagctattga 3350

 agatggcatt aactccttac cccaagctaa aaactgctct cttcccacag 3400

 tgcactcctc ctagtgtcct gccatctgat attacaatct accaccttat 3450

 tcagtcatta tcaccctttg atcctagcag attgtttggc tggcagtctg 3500

 ctaacacact agctatagga gatgcatgga gtcatctccc acatttctct 3550

 agccctgacc tggttaataa atatgctata gtggaacgtc tgaattttgc 3600

 ttattattta cataatgggc ggccatcatt tgcatttggt acttttctgg 3650

 tccaggaatt aatcaagagc aagactccca agcagctgat ccagcaagta 3700

 ggcaatgaag cctatgttat agggctctcc tccttccaca taccttcaat 3750

 aggagctgca tgtgtttgtt tcttagaatt gcttggcctt gacagcctca 3800

 agctcagagt tgatatgaaa gtggccaata taattttgag ctacaagtgc 3850

 agaaatgaag atgctcagta cagctttatc agagagtctg tagccgaaaa 3900

 actatctaaa ctagctgatg gtgaaaagac aaccacagaa gaattgcttg 3950

 ttctcttaga agaaggtaca tggaacagca ttcagcaaca ggaaataaag 4000

 aggttatcca gtgaatctag cagccaatgg gcattagtgg tgcagttctg 4050

 caggctacac aatatgaaac taagcatatc ttaccttaga gaatgtgcca 4100

 aagcaaatga ttggctgcag ttcattattc acagccaact ccacaactac 4150

 cacccagcag aggtgaaatc ccttatccag tacttcagcc cagtcattca 4200

 agaccactta aggctggctt ttgagaactt gccctcagtg cccacctcca 4250

 aaatggacag cgatcaagtc tgcaataagt gcccccagga acttcaagga 4300

 agcaaacaag agatgaccga tttatttgaa attctgctcc aatgctcaga 4350

 ggagccagac tcctggcact ggcttctggt tgaagcagtg aaacaacagg 4400

 cccctatcct cagtgttctg gcctcatgtc tccagggtgc cagtgccatt 4450

 tcttgtctct gtgtttggat catcacttct gtggaggaca atgttgcaac 4500

 tgaagcaatg ggacacattc aggactcaac agaggaccat acctggaacc 4550

 ttgaggatct ttcagtcatc tggagaacat tattaacaag acaaaagagc 4600

 aaaactctca tcagaggttt ccagcttttc tttaaggatt ccccgttact 4650

 actggtgatg gagatgtatg aactgtgtat gttcttcagg aattataaag 4700

 aagctgaagc taaacttctg gagtttcaga agagccttga aacgcttaac 4750

 acagcagcca caaaggtcca ccctgtcatc cctgccatgt ggctggagga 4800

 tcaggtgtgt ttccttttga agcttatgct acagcagtgt aagacccagt 4850

 atgagctggg gaagctttta cagctctttg ttgaaagaga gcatctcttc 4900

 tctgatggtc cagatgtgaa aaagctttgc atcctttgcc agattttgaa 4950

 ggatacatcc atagccatta atcatacaat tattaccagc tacagcattg 5000

 agaatcttca gcatgaatgt agatctattt tggaaagact gcagacagat 5050

 ggacaattcg ctttggccag gagggtagca gaattagctg agttacctgt 5100

 ggacaacttg gttattaaag agataacaca ggaaatgcag accctaaaac 5150

 acattgaaca gtggtcacta aaacaagcaa gaattgactt ctggaaaaaa 5200

 tgccatgaga attttaagaa aaattcaatt tcaagcaaag cagcttcttc 5250

 ctttttctca acccaggccc atgtggcatg tgagcaccca actggatgga 5300

 gcagcatgga ggagcgccat ctgctgctca ccttggcagg gcactggctt 5350

 gcccaggagg acgtggtgcc cttggataag ctggaggagc tggagaagca 5400

 gatctggctg tgccgcatca cccagcacac tcttggaaga aatcaggagg 5450

 aaacagagcc cagattttct cgacagatct caactagtgg tgaactttcc 5500

 tttgatagtt tagccagtga gttttccttc tccaagttgg ctgctctgaa 5550

 cacatcaaaa tacttagaac ttaacagcct tccatccaaa gagacatgcg 5600

 agaatagatt ggattggaaa gagcaggagt cactaaactt tttgattggg 5650

 cgcctactgg atgatggctg tgtgcatgaa gcaagtagag tatgccggta 5700

 ttttcatttt tataatccag atgtcgcctt ggtattgcac tgcagagcac 5750

 tggcctcagg ggaagctagt atggaggatc tgcacccaga gatccatgct 5800

 ctcctacaaa gtgctgagct gcttgaggaa gaagcacccg acattcccct 5850

 aaggagagtc cacagcactt caagtctgga tagtcagaag tttgtgacag 5900

 tgccctccag taatgaagtg gtaactaacc tggaagtgct gacaagcaaa 5950

 tgcctccatg ggaagaacta ctgtcgacag gtcctctgtc tgtatgatct 6000

 tgccaaggag ttgggctgtt cctacacaga tgttgctgct caggatggtg 6050

 aagccatgct ccggaaaatc ttggcctctc agcagcctga ccgatgcaaa 6100

 cgagcccagg ccttcatcag cacacagggc cttaagccag atactgtggc 6150

 tgaactcgtg gcagaagagg tgacacggga gctgcttact tcatcacagg 6200

 gaacaggaca taagcagatg ttcaacccaa cagaggaaag ccagacattt 6250

 cttcagctga ccactctgtg tcaagaccgc acattggtag gcatgaagtt 6300

 gttggataag atttcctccg ttccccatgg ggaactgtct tgcaccacag 6350

 agctcctgat cctggcccat cattgcttca ccctgacgtg ccacatggag 6400

 ggcatcatcc gagtcctaca ggccgcccac atgctcacag ataaccacct 6450

 ggcccccagt gaggagtatg ggctggtggt acggctcctc actggcattg 6500

 gaaggtacaa cgagatgaca tacatatttg atttgctgca taaaaagcac 6550

 tactttgaag tgctaatgag gaagaagttg gatccgagtg gtaccctgaa 6600

 aacagccctg ctggactaca tcaaacgctg ccgtcctgga gacagtgaaa 6650

 agcacaatat gattgccctg tgcttcagca tgtgccggga gattggcgag 6700

 aaccacgagg cagctgcccg catccaactg aaattgattg agtctcagcc 6750

 ctgggaggac agcctcaagg atgggcacca gctgaaacaa ctgctgctga 6800

 aggccctgac tctgatgttg gatgcagcag agagttatgc caaggactcc 6850

 tgtgtgcgac aggcccagca ctgtcagcgg ctcaccaagt tgataactct 6900

 gcagattcac tttctgaaca ctggccagaa cacaatgctc atcaacttgg 6950

 gccgccacaa gctgatggac tgtattctgg ccctacctcg gttctaccag 7000

 gcttctattg tggctgaggc ctacgatttt gttccagatt gggctgaaat 7050

 tttataccag caagtgattc ttaaaggaga ctttaattac ttggaagaat 7100

 ttaagcagca aaggttatta aagtccagta tatttgaaga gatttccaaa 7150

 aaatataaac aacatcagcc tactgacatg gtcatggaaa acctgaagaa 7200

 attactcaca tattgtgaag atgtttacct gtattacaag ttggcatacg 7250

 aacacaagtt ttatgaaatt gtaaatgtgc ttctgaagga ccctcagaca 7300

 ggttgctgtc taaaggacat gctagcaggt tagatgattt cataggtgtc 7350

 tgttttcttg tactgttagc agattctgac agatgtgatg agaagaagaa 7400

 tgcattggag atctttgcta aagttgaaca atcccggtac tgtaccatat 7450

 cagtcctttg tgggtagtag gtagcaagta agaaactttt caggaggaaa 7500

 ttcctattta aaatagattg attttagatg attgttcatc cacaccattt 7550

 tatatagata ctagtattaa gatcaaaagc ttcctcttcc tcaggacagc 7600

 ttctacttta gatgatccaa taatgattaa agaatacctg tacctgcaga 7650

 ttccagtttc aaagaaattt aattattatt tacacagtta aggaacaggt 7700

 gatacatttt catttgttag aaactgatct ttctgtaata aaatagattt 7750

 tc 7752

<210> 904
<211> 2000
<212> PRT
<213> Homo sapien

<400> 904
 Met Ala Ala Glu Glu Gly Val Ala Ser Ala Ala Ser Ala Gly Gly
   1               5                  10                  15

 Ser Trp Gly Thr Ala Ala Met Gly Arg Val Leu Pro Met Leu Leu
                  20                  25                  30

 Val Pro Val Pro Ala Glu Ala Met Gly Gln Leu Gly Ser Arg Ala
                  35                  40                  45

 Gln Leu Arg Thr Gln Pro Glu Ala Leu Gly Ser Leu Thr Ala Ala
                  50                  55                  60

 Gly Ser Leu Gln Val Leu Ser Leu Thr Pro Gly Ser Arg Gly Gly
                  65                  70                  75

 Gly Arg Cys Cys Leu Glu Gly Pro Phe Trp His Phe Leu Trp Glu
                  80                  85                  90

 Asp Ser Arg Asn Ser Ser Thr Pro Thr Glu Lys Pro Lys Leu Leu
                  95                 100                 105

 Ala Leu Gly Glu Asn Tyr Glu Leu Leu Ile Tyr Glu Phe Asn Leu
                 110                 115                 120

 Lys Asp Gly Arg Cys Asp Ala Thr Ile Leu Tyr Ser Cys Ser Arg
                 125                 130                 135

 Glu Ala Leu Gln Lys Leu Ile Asp Asp Gln Asp Ile Ser Ile Ser
                 140                 145                 150

 Leu Leu Ser Leu Arg Ile Leu Ser Phe His Asn Asn Thr Ser Leu
                 155                 160                 165

 Leu Phe Ile Asn Lys Cys Val Ile Leu His Ile Ile Phe Pro Glu
                 170                 175                 180

 Arg Asp Ala Ala Ile Arg Val Leu Asn Cys Phe Thr Leu Pro Leu
                 185                 190                 195

 Pro Ala Gln Ala Val Asp Met Ile Ile Asp Thr Gln Leu Cys Arg
                 200                 205                 210

 Gly Ile Leu Phe Val Leu Ser Ser Leu Gly Trp Ile Tyr Ile Phe
                 215                 220                 225

 Asp Val Val Asp Gly Thr Tyr Val Ala His Val Asp Leu Ala Leu
                 230                 235                 240

 His Lys Glu Asp Met Cys Asn Glu Gln Gln Gln Glu Pro Ala Lys
                 245                 250                 255

 Ile Ser Ser Phe Thr Ser Leu Lys Val Ser Gln Asp Leu Asp Val
                 260                 265                 270

 Ala Val Ile Val Ser Ser Ser Asn Ser Ala Val Ala Leu Asn Leu
                 275                 280                 285

 Asn Leu Tyr Phe Arg Gln His Pro Gly His Leu Leu Cys Glu Arg
                 290                 295                 300

 Ile Leu Glu Asp Leu Pro Ile Gln Gly Pro Lys Gly Val Asp Glu
                 305                 310                 315

 Asp Asp Pro Val Asn Ser Ala Tyr Asn Met Lys Leu Ala Lys Phe
                 320                 325                 330

 Ser Phe Gln Ile Asp Arg Ser Trp Lys Ala Gln Leu Ser Ser Leu
                 335                 340                 345

 Asn Glu Thr Ile Lys Asn Ser Lys Leu Glu Val Ser Cys Cys Ala
                 350                 355                 360

 Pro Trp Phe Gln Asp Ile Leu His Leu Glu Ser Pro Glu Ser Gly
                 365                 370                 375

 Asn His Ser Thr Ser Val Gln Ser Trp Ala Phe Ile Pro Gln Asp
                 380                 385                 390

 Ile Met His Gly Gln Tyr Asn Val Leu Gln Lys Asp His Ala Lys
                 395                 400                 405

 Thr Ser Asp Pro Gly Arg Ser Trp Lys Ile Met His Ile Ser Glu
                 410                 415                 420

 Gln Glu Glu Pro Ile Glu Leu Lys Cys Val Ser Val Thr Gly Phe
                 425                 430                 435

 Thr Ala Leu Phe Thr Trp Glu Val Glu Arg Met Gly Tyr Thr Ile
                 440                 445                 450

 Thr Leu Trp Asp Leu Glu Thr Gln Gly Met Gln Cys Ser Ser Leu
                 455                 460                 465

 Gly Thr Lys Cys Ile Pro Val Asp Ser Ser Gly Asp Gln Gln Leu
                 470                 475                 480

 Cys Phe Val Leu Thr Glu Asn Gly Leu Ser Leu Ile Leu Phe Gly
                 485                 490                 495

 Leu Thr Gln Glu Glu Phe Leu Asn Arg Leu Met Ile His Gly Ser
                 500                 505                 510

 Ala Ser Thr Val Asp Thr Leu Cys His Leu Asn Gly Trp Gly Arg
                 515                 520                 525

 Cys Ser Ile Pro Ile His Ala Leu Glu Ala Gly Ile Glu Asn Arg
                 530                 535                 540

 Gln Leu Asp Thr Val Asn Phe Phe Leu Lys Ser Lys Glu Asn Leu
                 545                 550                 555

 Phe Asn Pro Ser Ser Lys Ser Ser Val Ser Asp Gln Phe Asp His
                 560                 565                 570

 Leu Ser Ser His Leu Tyr Leu Arg Asn Val Glu Glu Leu Ile Pro
                 575                 580                 585

 Ala Leu Asp Leu Leu Cys Ser Ala Ile Arg Glu Ser Tyr Ser Glu
                 590                 595                 600

 Pro Gln Ser Lys His Phe Ser Glu Gln Leu Leu Asn Leu Thr Leu
                 605                 610                 615

 Ser Phe Leu Asn Asn Gln Ile Lys Glu Leu Phe Ile His Thr Glu
                 620                 625                 630

 Glu Leu Asp Glu His Leu Gln Lys Gly Val Asn Ile Leu Thr Ser
                 635                 640                 645

 Tyr Ile Asn Glu Leu Arg Thr Phe Met Ile Lys Phe Pro Trp Lys
                 650                 655                 660

 Leu Thr Asp Ala Ile Asp Glu Tyr Asp Val His Glu Asn Val Pro
                 665                 670                 675

 Lys Val Lys Glu Ser Asn Ile Trp Lys Lys Leu Ser Phe Glu Glu
                 680                 685                 690

 Val Ile Ala Ser Ala Ile Leu Asn Asn Lys Ile Pro Glu Ala Gln
                 695                 700                 705

 Thr Phe Phe Arg Ile Asp Ser His Ser Ala Gln Lys Leu Glu Glu
                 710                 715                 720

 Leu Ile Gly Ile Gly Leu Asn Leu Val Phe Asp Asn Leu Lys Lys
                 725                 730                 735

 Asn Asn Ile Lys Glu Ala Ser Glu Leu Leu Lys Asn Met Gly Phe
                 740                 745                 750

 Asp Val Lys Gly Gln Leu Leu Lys Ile Cys Phe Tyr Thr Thr Asn
                 755                 760                 765

 Lys Asn Ile Arg Asp Phe Leu Val Glu Ile Leu Lys Glu Lys Asn
                 770                 775                 780

 Tyr Phe Ser Glu Lys Glu Lys Arg Thr Ile Asp Phe Val His Gln
                 785                 790                 795

 Val Glu Lys Leu Tyr Leu Gly His Phe Gln Glu Asn Met Gln Ile
                 800                 805                 810

 Gln Ser Phe Pro Arg Tyr Trp Ile Lys Glu Gln Asp Phe Phe Lys
                 815                 820                 825

 His Lys Ser Val Leu Asp Ser Phe Leu Lys Tyr Asp Cys Lys Asp
                 830                 835                 840

 Glu Phe Asn Lys Gln Asp His Arg Ile Val Leu Asn Trp Ala Leu
                 845                 850                 855

 Trp Trp Asp Gln Leu Thr Gln Glu Ser Ile Leu Leu Pro Arg Ile
                 860                 865                 870

 Ser Pro Glu Glu Tyr Lys Ser Tyr Ser Pro Glu Ala Leu Trp Arg
                 875                 880                 885

 Tyr Leu Thr Ala Arg His Asp Trp Leu Asn Ile Ile Leu Trp Ile
                 890                 895                 900

 Gly Glu Phe Gln Thr Gln His Ser Tyr Ala Ser Leu Gln Gln Asn
                 905                 910                 915

 Lys Trp Pro Leu Leu Thr Val Asp Val Ile Asn Gln Asn Thr Ser
                 920                 925                 930

 Cys Asn Asn Tyr Met Arg Asn Glu Ile Leu Asp Lys Leu Ala Arg
                 935                 940                 945

 Asn Gly Val Phe Leu Ala Ser Glu Leu Glu Asp Phe Glu Cys Phe
                 950                 955                 960

 Leu Leu Arg Leu Ser Arg Ile Gly Gly Val Ile Gln Asp Thr Leu
                 965                 970                 975

 Pro Val Gln Asn Tyr Lys Thr Lys Glu Gly Trp Asp Phe His Ser
                 980                 985                 990

 Gln Phe Ile Leu Tyr Cys Leu Glu His Ser Leu Gln His Leu Leu
                 995                1000                1005

 Tyr Val Tyr Leu Asp Cys Tyr Lys Leu Ser Pro Glu Asn Cys Pro
                1010                1015                1020

 Phe Leu Glu Lys Lys Glu Leu His Glu Ala His Pro Trp Phe Glu
                1025                1030                1035

 Phe Leu Val Gln Cys Arg Gln Val Ala Ser Asn Leu Thr Asp Pro
                1040                1045                1050

 Lys Leu Ile Phe Gln Ala Ser Leu Ala Asn Ala Gln Ile Leu Ile
                1055                1060                1065

 Pro Thr Asn Gln Ala Ser Val Ser Ser Met Leu Leu Glu Gly His
                1070                1075                1080

 Thr Leu Leu Ala Leu Ala Thr Thr Met Tyr Ser Pro Gly Gly Val
                1085                1090                1095

 Ser Gln Val Val Gln Asn Glu Glu Asn Glu Asn Cys Leu Lys Lys
                1100                1105                1110

 Val Asp Pro Gln Leu Leu Lys Met Ala Leu Thr Pro Tyr Pro Lys
                1115                1120                1125

 Leu Lys Thr Ala Leu Phe Pro Gln Cys Thr Pro Pro Ser Val Leu
                1130                1135                1140

 Pro Ser Asp Ile Thr Ile Tyr His Leu Ile Gln Ser Leu Ser Pro
                1145                1150                1155

 Phe Asp Pro Ser Arg Leu Phe Gly Trp Gln Ser Ala Asn Thr Leu
                1160                1165                1170

 Ala Ile Gly Asp Ala Trp Ser His Leu Pro His Phe Ser Ser Pro
                1175                1180                1185

 Asp Leu Val Asn Lys Tyr Ala Ile Val Glu Arg Leu Asn Phe Ala
                1190                1195                1200

 Tyr Tyr Leu His Asn Gly Arg Pro Ser Phe Ala Phe Gly Thr Phe
                1205                1210                1215

 Leu Val Gln Glu Leu Ile Lys Ser Lys Thr Pro Lys Gln Leu Ile
                1220                1225                1230

 Gln Gln Val Gly Asn Glu Ala Tyr Val Ile Gly Leu Ser Ser Phe
                1235                1240                1245

 His Ile Pro Ser Ile Gly Ala Ala Cys Val Cys Phe Leu Glu Leu
                1250                1255                1260

 Leu Gly Leu Asp Ser Leu Lys Leu Arg Val Asp Met Lys Val Ala
                1265                1270                1275

 Asn Ile Ile Leu Ser Tyr Lys Cys Arg Asn Glu Asp Ala Gln Tyr
                1280                1285                1290

 Ser Phe Ile Arg Glu Ser Val Ala Glu Lys Leu Ser Lys Leu Ala
                1295                1300                1305

 Asp Gly Glu Lys Thr Thr Thr Glu Glu Leu Leu Val Leu Leu Glu
                1310                1315                1320

 Glu Gly Thr Trp Asn Ser Ile Gln Gln Gln Glu Ile Lys Arg Leu
                1325                1330                1335

 Ser Ser Glu Ser Ser Ser Gln Trp Ala Leu Val Val Gln Phe Cys
                1340                1345                1350

 Arg Leu His Asn Met Lys Leu Ser Ile Ser Tyr Leu Arg Glu Cys
                1355                1360                1365

 Ala Lys Ala Asn Asp Trp Leu Gln Phe Ile Ile His Ser Gln Leu
                1370                1375                1380

 His Asn Tyr His Pro Ala Glu Val Lys Ser Leu Ile Gln Tyr Phe
                1385                1390                1395

 Ser Pro Val Ile Gln Asp His Leu Arg Leu Ala Phe Glu Asn Leu
                1400                1405                1410

 Pro Ser Val Pro Thr Ser Lys Met Asp Ser Asp Gln Val Cys Asn
                1415                1420                1425

 Lys Cys Pro Gln Glu Leu Gln Gly Ser Lys Gln Glu Met Thr Asp
                1430                1435                1440

 Leu Phe Glu Ile Leu Leu Gln Cys Ser Glu Glu Pro Asp Ser Trp
                1445                1450                1455

 His Trp Leu Leu Val Glu Ala Val Lys Gln Gln Ala Pro Ile Leu
                1460                1465                1470

 Ser Val Leu Ala Ser Cys Leu Gln Gly Ala Ser Ala Ile Ser Cys
                1475                1480                1485

 Leu Cys Val Trp Ile Ile Thr Ser Val Glu Asp Asn Val Ala Thr
                1490                1495                1500

 Glu Ala Met Gly His Ile Gln Asp Ser Thr Glu Asp His Thr Trp
                1505                1510                1515

 Asn Leu Glu Asp Leu Ser Val Ile Trp Arg Thr Leu Leu Thr Arg
                1520                1525                1530

 Gln Lys Ser Lys Thr Leu Ile Arg Gly Phe Gln Leu Phe Phe Lys
                1535                1540                1545

 Asp Ser Pro Leu Leu Leu Val Met Glu Met Tyr Glu Leu Cys Met
                1550                1555                1560

 Phe Phe Arg Asn Tyr Lys Glu Ala Glu Ala Lys Leu Leu Glu Phe
                1565                1570                1575

 Gln Lys Ser Leu Glu Thr Leu Asn Thr Ala Ala Thr Lys Val His
                1580                1585                1590

 Pro Val Ile Pro Ala Met Trp Leu Glu Asp Gln Val Cys Phe Leu
                1595                1600                1605

 Leu Lys Leu Met Leu Gln Gln Cys Lys Thr Gln Tyr Glu Leu Gly
                1610                1615                1620

 Lys Leu Leu Gln Leu Phe Val Glu Arg Glu His Leu Phe Ser Asp
                1625                1630                1635

 Gly Pro Asp Val Lys Lys Leu Cys Ile Leu Cys Gln Ile Leu Lys
                1640                1645                1650

 Asp Thr Ser Ile Ala Ile Asn His Thr Ile Ile Thr Ser Tyr Ser
                1655                1660                1665

 Ile Glu Asn Leu Gln His Glu Cys Arg Ser Ile Leu Glu Arg Leu
                1670                1675                1680

 Gln Thr Asp Gly Gln Phe Ala Leu Ala Arg Arg Val Ala Glu Leu
                1685                1690                1695

 Ala Glu Leu Pro Val Asp Asn Leu Val Ile Lys Glu Ile Thr Gln
                1700                1705                1710

 Glu Met Gln Thr Leu Lys His Ile Glu Gln Trp Ser Leu Lys Gln
                1715                1720                1725

 Ala Arg Ile Asp Phe Trp Lys Lys Cys His Glu Asn Phe Lys Lys
                1730                1735                1740

 Asn Ser Ile Ser Ser Lys Ala Ala Ser Ser Phe Phe Ser Thr Gln
                1745                1750                1755

 Ala His Val Ala Cys Glu His Pro Thr Gly Trp Ser Ser Met Glu
                1760                1765                1770

 Glu Arg His Leu Leu Leu Thr Leu Ala Gly His Trp Leu Ala Gln
                1775                1780                1785

 Glu Asp Val Val Pro Leu Asp Lys Leu Glu Glu Leu Glu Lys Gln
                1790                1795                1800

 Ile Trp Leu Cys Arg Ile Thr Gln His Thr Leu Gly Arg Asn Gln
                1805                1810                1815

 Glu Glu Thr Glu Pro Arg Phe Ser Arg Gln Ile Ser Thr Ser Gly
                1820                1825                1830

 Glu Leu Ser Phe Asp Ser Leu Ala Ser Glu Phe Ser Phe Ser Lys
                1835                1840                1845

 Leu Ala Ala Leu Asn Thr Ser Lys Tyr Leu Glu Leu Asn Ser Leu
                1850                1855                1860

 Pro Ser Lys Glu Thr Cys Glu Asn Arg Leu Asp Trp Lys Glu Gln
                1865                1870                1875

 Glu Ser Leu Asn Phe Leu Ile Gly Arg Leu Leu Asp Asp Gly Cys
                1880                1885                1890

 Val His Glu Ala Ser Arg Val Cys Arg Tyr Phe His Phe Tyr Asn
                1895                1900                1905

 Pro Asp Val Ala Leu Val Leu His Cys Arg Ala Leu Ala Ser Gly
                1910                1915                1920

 Glu Ala Ser Met Glu Asp Leu His Pro Glu Ile His Ala Leu Leu
                1925                1930                1935

 Gln Ser Ala Glu Leu Leu Glu Glu Glu Ala Pro Asp Ile Pro Leu
                1940                1945                1950

 Arg Arg Val His Ser Thr Ser Ser Leu Asp Ser Gln Lys Phe Val
                1955                1960                1965

 Thr Val Pro Ser Ser Asn Glu Val Val Thr Asn Leu Glu Val Leu
                1970                1975                1980

 Thr Ser Lys Cys Leu His Gly Lys Asn Tyr Cys Arg Gln Val Leu
                1985                1990                1995

 Cys Leu Tyr Asp Leu
                2000

<210> 905
<211> 1270
<212> DNA
<213> Homo sapien

<400> 905
 ggcacgaggc tgcgccggaa gtccctagcc aggcctggcg gtaaccttgg 50

 gggcctcact gcagccgccg ctgctgttgg agtgggcttt gcgagtctga 100

 acgttggcgg ggctaggctc gttaactgcc gagagcctcc gggtttgcgg 150

 tggaggacgc tgaggcccgt ggggggcagg cacccgggcg ccgggcctcc 200

 cagccgacat gtctctagtg gcggaagcct tcgtctccca gattgcagct 250

 gcagaacctt ggcctgaaaa tgctacatta tatcagcaat tgaaagggga 300

 gcaaatttta ctttctgaca atgcagcttc tcttgcagtg caggcctttt 350

 tgcaaatgtg taacttgcct atcaaagtag tttgtagggc aaatgcagaa 400

 tatatgtctc catctggtaa agtacctttt attcatgtgg gaaatcaagt 450

 agtatcagaa cttggtccaa tagtccaatt tgttaaagcc aagggccatt 500

 ctcttagtga tgggctggag gaagtccaaa aagcagaaat gaaagcttac 550

 atggaattag tcaacaatat gctgttgact gcagagctgt atcttcagtg 600

 gtgtgatgaa gctacagtag gggagatcac tcatgctagg tatggatctc 650

 cttacccttg gcctctgaat catattttgg cctatcaaaa acagtgggaa 700

 gtcaaacgta agatgaaagc tattggatgg ggaaagaaga ctctggacca 750

 ggtcttagag gatgtagacc agtgctgtca agctctctct caaagactgg 800

 gaacacaacc gtatttcttc aataagcagc ctactgaact tgacgcactg 850

 gtatttggcc atctatacac cattcttacc acacaattga caaatgatga 900

 actttctgag aaggtgaaaa actatagcaa cctccttgct ttctgtagga 950

 gaattgaaca gcactatttt gaagatcgtg gtaaaggcag gctgtcatag 1000

 agttatgtgt tagtctcagg agtcttaact tttgaaatat gttttacttg 1050

 aatgttacat tagatattgg tgtcagaatt ttaaaaccaa attactgctt 1100

 tttgaaacct caaattatat aatgtatctt atgtatgtgc tttatattgt 1150

 tatttgtgta tacattaaaa taattctgaa ttatttaatc tgatatgttg 1200

 tattctgtat cttgaaattt ttgtttcctt gaaacatgca tgcatttaaa 1250

 aataaagctt aaacaactgt 1270

<210> 906
<211> 263
<212> PRT
<213> Homo sapien

<400> 906
 Met Ser Leu Val Ala Glu Ala Phe Val Ser Gln Ile Ala Ala Ala
   1               5                  10                  15

 Glu Pro Trp Pro Glu Asn Ala Thr Leu Tyr Gln Gln Leu Lys Gly
                  20                  25                  30

 Glu Gln Ile Leu Leu Ser Asp Asn Ala Ala Ser Leu Ala Val Gln
                  35                  40                  45

 Ala Phe Leu Gln Met Cys Asn Leu Pro Ile Lys Val Val Cys Arg
                  50                  55                  60

 Ala Asn Ala Glu Tyr Met Ser Pro Ser Gly Lys Val Pro Phe Ile
                  65                  70                  75

 His Val Gly Asn Gln Val Val Ser Glu Leu Gly Pro Ile Val Gln
                  80                  85                  90

 Phe Val Lys Ala Lys Gly His Ser Leu Ser Asp Gly Leu Glu Glu
                  95                 100                 105

 Val Gln Lys Ala Glu Met Lys Ala Tyr Met Glu Leu Val Asn Asn
                 110                 115                 120

 Met Leu Leu Thr Ala Glu Leu Tyr Leu Gln Trp Cys Asp Glu Ala
                 125                 130                 135

 Thr Val Gly Glu Ile Thr His Ala Arg Tyr Gly Ser Pro Tyr Pro
                 140                 145                 150

 Trp Pro Leu Asn His Ile Leu Ala Tyr Gln Lys Gln Trp Glu Val
                 155                 160                 165

 Lys Arg Lys Met Lys Ala Ile Gly Trp Gly Lys Lys Thr Leu Asp
                 170                 175                 180

 Gln Val Leu Glu Asp Val Asp Gln Cys Cys Gln Ala Leu Ser Gln
                 185                 190                 195

 Arg Leu Gly Thr Gln Pro Tyr Phe Phe Asn Lys Gln Pro Thr Glu
                 200                 205                 210

 Leu Asp Ala Leu Val Phe Gly His Leu Tyr Thr Ile Leu Thr Thr
                 215                 220                 225

 Gln Leu Thr Asn Asp Glu Leu Ser Glu Lys Val Lys Asn Tyr Ser
                 230                 235                 240

 Asn Leu Leu Ala Phe Cys Arg Arg Ile Glu Gln His Tyr Phe Glu
                 245                 250                 255

 Asp Arg Gly Lys Gly Arg Leu Ser
                 260

<210> 907
<211> 13449
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 11967, 12008, 12013
<223> Unknown base

<400> 907
 gcggccgcgt cgacgcggcg gcggcagcgg cgtcggctcg gggttctccg 50

 ggagaggggg agtgcgcggc ggccgcagct gccacaaacc aggtgaagct 100

 ttgttctaag aatatttgtt tcatctagtt tatgagtcca aatgatatag 150

 actgtaaatg tcacagcagt ggtgaaagac tgctcggtca tgagcaccga 200

 cagtaactca ctggcacgtg aatttctgac cgatgtcaac cggctttgca 250

 atgcagtggt ccagagggtg gaggccaggg aggaagaaga ggaggagacg 300

 cacatggcaa cccttggaca gtaccttgtc catggtcgag gatttctatt 350

 acttaccaag ctaaattcta taattgatca ggcattgaca tgtagagaag 400

 aactcctgac tcttcttctg tctctccttc cactggtatg gaagatacct 450

 gtccaagaag aaaaggcaac agattttaac ctaccgctct cagcagatat 500

 aatcctgacc aaagaaaaga actcaagttc acaaagatcc actcaggaaa 550

 aattacattt agaaggaagt gccctgtcta gtcaggtttc tgcaaaagta 600

 aatgtttttc gaaaaagcag acgacagcgt aaaattaccc atcgctattc 650

 tgtaagagat gcaagaaaga cacagctctc cacctcagat tcagaagcca 700

 attcagatga aaaaggcata gcaatgaata agcatagaag gccccatctg 750

 ctgcatcatt ttttaacatc gtttcctaaa caagaccacc ccaaagctaa 800

 acttgaccgc ttagcaacca aagaacagac tcctccagat gctatggctt 850

 tggaaaattc cagagagatt attccaagac aggggtcaaa cactgacatt 900

 ttaagtgagc cagctgcctt gtctgttatc agtaacatga acaattctcc 950

 atttgactta tgtcatgttt tgttatcttt attagaaaaa gtttgtaagt 1000

 ttgacgttac cttgaatcat aattctcctt tagcagccag tgtagtgccc 1050

 acactaactg aattcctagc aggctttggg gactgctgca gtctgagcga 1100

 caacttggag agtcgagtag tttctgcagg ttggaccgaa gaaccggtgg 1150

 ctttgattca aaggatgctc tttcgaacag tgttgcatct tctgtcagta 1200

 gatgttagta ctgcagagat gatgccagaa aatcttagga aaaatttaac 1250

 tgaattgctt agagcagctt taaaaattag aatatgccta gaaaagcagc 1300

 ctgacccttt tgcaccaaga caaaagaaaa cactgcagga ggttcaggaa 1350

 gattttgtgt tttcaaagta tcgtcataga gcccttcttt tacctgagct 1400

 tttggaagga gttcttcaga ttctgatctg ttgtcttcaa agtgcagctt 1450

 caaatccctt ctacttcagt caagccatgg atttggttca agaattcatt 1500

 cagcatcatg gatttaattt atttgaaaca gcagttcttc aaatggaatg 1550

 gctggtttta agagatggag ttcctcccga ggcctcagag catttgaaag 1600

 ccctaataaa tagtgtgatg aaaataatga gcactgtcaa aaaagtgaaa 1650

 tcagagcaac ttcatcattc gatgtgtaca agaaaaaggc acagacgatg 1700

 tgaatattct cattttatgc atcatcaccg agatctctca ggtcttctgg 1750

 tttcggcttt taaaaaccag gtttccaaaa acccatttga agagactgca 1800

 gatggagatg tttattatcc tgagcggtgc tgttgcattg cagtgtgtgc 1850

 ccatcagtgc ttgcgcttac tacagcaggc ttccttgagc agcacttgtg 1900

 tccagatcct atcgggtgtt cataacattg gaatatgctg ttgtatggat 1950

 cccaaatctg taatcattcc tttgctccat gcttttaaat tgccagcact 2000

 gaaaaatttt cagcagcata tattgaatat ccttaacaaa cttattttgg 2050

 atcagttagg aggagcagag atatcaccaa aaattaaaaa agcagcttgt 2100

 aatatttgta ctgttgactc tgaccaacta gcccaattag aagagacact 2150

 gcagggaaac ttatgtgatg ctgaactctc ctcaagttta tccagtcctt 2200

 cttacagatt tcaagggatc ctgcccagca gtggatctga agatttgttg 2250

 tggaaatggg atgctttaaa ggcttatcag aactttgttt ttgaagaaga 2300

 cagattacat agtatacaga ttgcaaatca catttgcaat ttaatccaga 2350

 aaggcaatat agttgttcag tggaaattat ataattacat atttaatcct 2400

 gtgctccaaa gaggagttga attagcacat cattgtcaac acctaagcgt 2450

 tacttcagct caaagtcatg tatgtagcca tcataaccag tgcttgcctc 2500

 aggacgtgct tcagatttat gtaaaaactc tgcctatcct gcttaaatcc 2550

 agggtaataa gagatttgtt tttgagttgt aatggagtaa gtcaaataat 2600

 cgaattaaat tgcttaaatg gtattcgaag tcattctcta aaagcatttg 2650

 aaactctgat aatcagccta ggggagcaac agaaagatgc ctcagttcca 2700

 gatattgatg ggatagacat tgaacagaag gagttgtcct ctgtacatgt 2750

 gggtacttct tttcatcatc agcaagctta ttcagattct cctcagagtc 2800

 tcagcaaatt ttatgctggc ctcaaagaag cttatccaaa gagacggaag 2850

 actgttaacc aagatgttca tatcaacaca ataaacctat tcctctgtgt 2900

 ggctttttta tgcgtaagta aagaagcaga gtctgacagg gagtcggcca 2950

 atgactcaga agatacttct ggctatgaca gcacagccag cgagccttta 3000

 agtcatatgc tgccatgtat atctctcgag agccttgtct tgccttctcc 3050

 tgaacatatg caccaagcag cagacatttg gtctatgtgt cgttggatct 3100

 acatgttgag ttcagtgttc cagaaacagt tttataggct tggtggtttc 3150

 cgagtatgcc ataagttaat atttatgata atacagaaac tgttcagaag 3200

 tcacaaagag gagcaaggaa aaaaggaggg agatacaagt gtaaatgaaa 3250

 accaggattt aaacagaatt tctcaaccta agagaactat gaaggaagat 3300

 ttattatctt tggctataaa aagtgacccc ataccatcag aactaggtag 3350

 tctaaaaaag agtgctgaca gtttaggtaa attagagtta cagcatattt 3400

 cttccataaa tgtggaagaa gtttcagcta ctgaagccgc tcccgaggaa 3450

 gcaaagctat ttacaagtca agaaagtgag acctcacttc aaagtatacg 3500

 acttttggaa gcccttctgg ccatttgtct tcatggtgcc agaactagtc 3550

 aacagaagat ggaattggag ttacctaatc agaacttgtc tgtggaaagt 3600

 atattatttg aaatgaggga ccatctttcc cagtcaaagg tgattgaaac 3650

 acaactagca aagccgttat ttgatgccct gcttcgagtt gccctcggga 3700

 attattcagc agattttgaa cataatgatg ctatgactga gaagagtcat 3750

 caatctgcag aagaattgtc atcccagcct ggtgattttt cagaagaagc 3800

 tgaggattct cagtgttgta gttttaaact tttagttgaa gaagaaggtt 3850

 acgaagcaga tagtgaaagc aatcctgaag atggcgaaac ccaggatgat 3900

 ggggtagact taaagtctga aacagaaggt ttcagtgcat caagcagtcc 3950

 aaatgactta ctcgaaaacc tcactcaagg ggaaataatt tatcctgaga 4000

 tttgtatgct ggaattaaat ttgctttctg ctagtaaagc caaacttgat 4050

 gtgcttgccc atgtatttga gagttttttg aaaattatta ggcagaaaga 4100

 aaagaatgtt tttctgctca tgcaacaggg aactgtgaaa aatcttttag 4150

 gagggttctt gagtatttta acacaggatg attctgattt tcaagcatgc 4200

 cagagagtat tggtggatct tttggtatct ttgatgagtt caagaacatg 4250

 ttcagaagag ctaacccttc ttttgagaat atttctggag aaatctcctt 4300

 gtacaaaaat tcttcttctg ggtattctga aaattattga aagtgatact 4350

 actatgagcc cttcacagta tctaaccttc cctttactgc acgctccaaa 4400

 tttaagcaac ggtgtttcat cacaaaagta tcctgggatt ttaaacagta 4450

 aggccatggg tttattgaga agagcacgag tttcacggag caagaaagag 4500

 gctgatagag agagttttcc ccatcggctg ctttcatctt ggcacatagc 4550

 cccagtccac ctgccgttgc tggggcaaaa ctgctggcca cacctatcag 4600

 aaggtttcag tgtttccctg tggtttaatg tggagtgtat ccatgaagct 4650

 gagagtacta cagaaaaagg aaagaagata aagaaaagaa acaaatcatt 4700

 aattttacca gatagcagtt ttgatggtac agagagcgac agaccagaag 4750

 gtgcagagta cataaatcct ggtgaaagac tcatagaaga aggatgtatt 4800

 catataattt cactgggatc caaagcgttg atgatccaag tgtgggctga 4850

 tccccacaat gccactctta tctttcgtgt gtgcatggat tcaaatgatg 4900

 acatgaaagc tgttttacta gcacaggttg aatcacagga gaatattttc 4950

 ctcccaagca aatggcaaca tttagtactc acctacttac agcagcccca 5000

 agggaaaagg aggattcatg ggaaaatctc catatgggtc tctggacaga 5050

 ggaagcctga tgttactttg gattttatgc ttccaagaaa aacaagtttg 5100

 tcatctgata gcaataaaac attttgcatg attggccatt gtttatcatc 5150

 ccaagaagag tttttgcagt tggctggaaa atgggacctg ggaaatttgc 5200

 ttctcttcaa cggagctaag gttggttcac aagaggcctt ttatctgtat 5250

 gcttgtggac ccaaccatac atctgtaatg ccatgtaagt atggcaagcc 5300

 agtcaatgac tactccaaat atattaataa agaaattttg cgatgtgaac 5350

 aaatcagaga actttttatg accaagaaag atgtggatat tggtctctta 5400

 attgaaagtc tttcagttgt ttatacaact tactgtcctg ctcagtatac 5450

 catctatgaa ccagtgatta gacttaaagg tcaaatgaaa acccaactct 5500

 ctcaaagacc cttcagctca aaagaagttc agagcatctt attagaacct 5550

 catcatctaa agaatctcca acctactgaa tataaaacta ttcaaggcat 5600

 tctgcacgaa attggtggaa ctggcatatt tgtttttctc tttgccaggg 5650

 ttgttgaact cagtagctgt gaagaaactc aagcattagc actgcgagtt 5700

 atactctcat taattaaata caaccaacaa agagtacatg aattagaaaa 5750

 ttgtaatgga ctttctatga ttcatcaggt gttgatcaaa caaaaatgca 5800

 ttgttgggtt ttacattttg aagacccttc ttgaaggatg ctgtggtgaa 5850

 gatattattt atatgaatga gaatggagag tttaagttgg atgtagactc 5900

 taatgctata atccaagatg ttaagctgtt agaggaacta ttgcttgact 5950

 ggaagatatg gagtaaagca gagcaaggtg tttgggaaac tttgctagca 6000

 gctctagaag tcctcatcag agcagatcac caccagcaga tgtttaatat 6050

 taagcagtta ttgaaagctc aagtggttca tcactttcta ctgacttgtc 6100

 aggttttgca ggaatacaaa gaggggcaac tcacacccat gccccgagag 6150

 gtttgtagat catttgtgaa aattatagca gaagtccttg gatctcctcc 6200

 agatttggaa ttattgacaa ttatcttcaa tttcctttta gcagttcacc 6250

 ctcctactaa tacttacgtt tgtcacaatc ccacgaactt ctacttttct 6300

 ttgcacatag atggcaagat ctttcaggag aaagtgcggt caatcatgta 6350

 cctgaggcat tccagcagtg gaggaaggtc ccttatgagc cctggattta 6400

 tggtaataag cccatctggt tttactgctt caccatatga aggagagaat 6450

 tcctctaata ttattccaca acagatggcc gcccatatgc tgcgttctag 6500

 aagcctacca gcattcccta cttcttcact actaacgcaa tcacaaaaac 6550

 tgactggaag tttgggttgt agtatcgaca ggttacaaaa tattgcagat 6600

 acttatgttg ccacccaatc aaagaaacaa aattctttgg ggagttccga 6650

 cacactgaaa aaaggcaaag aggacgcatt catcagtagc tgtgagtctg 6700

 caaaaactgt ttgtgaaatg gaagctgtcc tctcagccca ggtctctgtc 6750

 agtgatgtcc caaagggagt gctgggattt ccagtggtca aagcagatca 6800

 taaacagttg ggagcagaac ccaggtcaga agatgacagt cctggggatg 6850

 agtcctgccc acgccgacct gattacctaa agggattggc ctccttccag 6900

 cgaagccaca gcactattgc aagccttggg ctagcttttc cttcacagaa 6950

 cggatctgca gctgttggcc gttggccaag tcttgttgat agaaacactg 7000

 atgattggga aaactttgcc tattctcttg gttatgagcc aaattacaac 7050

 cgaactgcaa gtgctcacag tgtaactgaa gactgtttgg tacctatatg 7100

 ctgtggatta tatgaactcc taagtggggt tcttcttatc ctgcctgatg 7150

 ttttgcttga agatgtgatg gacaagctta ttcaagcaga tacacttttg 7200

 gtcctcgtta accacccatc accagctata caacaaggtg ttattaaact 7250

 attagatgca tattttgcta gagcatctaa ggaacaaaaa gataaatttc 7300

 tgaagaatcg tggattttcc ttgctagcca accagttgta tcttcatcga 7350

 ggaactcaag aattgttaga atgcttcatc gaaatgttct ttggtcgaca 7400

 tattggcctt gatgaagaat ttgatctgga agatgtgaga aacatgggat 7450

 tgtttcagaa gtggtctgtc attcctattc tgggactaat agagacctct 7500

 ctatatgaca acatactctt gcataatgct cttttacttc ttctccaaat 7550

 tttaaattct tgttctaagg tagcagatat gttgctggat aatggtctac 7600

 tctatgtgtt atgtaataca gtagcagccc tgaatggatt agaaaagaac 7650

 attcccatga gtgaatataa attgcttgct tgtgatatac agcaactttt 7700

 catagcagtt acaattcatg cttgcagttc ctcaggctca caatatttta 7750

 gggttattga agaccttatt gtaatgcttg gatatcttca aaatagcaaa 7800

 aacaagagga cacaaaatat ggctgttgca ctacagctta gagttctcca 7850

 ggctgctatg gaatttataa ggaccaccgc aaatcatgac tctgaaaacc 7900

 tcacagattc actccagtca ccttctgctc cccatcatgc agtagttcaa 7950

 aagcggaaaa gcattgctgg tcctcgaaaa tttccccttg ctcaaactga 8000

 atcgcttctg atgaaaatgc gttcagtggc aaatgatgag cttcatgtga 8050

 tgatgcaacg gagaatgagc caagagaacc ctagccaagc aactgaaacg 8100

 gaacttgcgc agagactaca gaggctcact gttttagcag tcaacaggat 8150

 tatttatcaa gaatttaatt cagacattat tgacattttg agaactccag 8200

 aaaatgtaac tcaaagcaag acctcagttt tccagaccga aatttctgag 8250

 gaaaatattc atcatgaaca gtcttctgtt ttcaatccat ttcagaaaga 8300

 aatttttaca tatctggtag aaggattcaa agtatctatt ggttcaagta 8350

 aagccagtgg ttccaagcag caatggacta aaattctgtg gtcttgtaag 8400

 gagaccttcc gaatgcagct tgggagacta ctagtgcata ttttgtcgcc 8450

 agcccacgct gcacaagaga gaaagcaaat ttttgaaata gttcatgaac 8500

 caaatcatca ggaaatacta cgagactgtc tcagcccatc cctacaacat 8550

 ggagccaagt tagttttgta tttgtcagag ttgatacata atcaccaagg 8600

 tgaattgact gaagaagagc taggcacagc agaactgctt atgaatgctt 8650

 tgaagttatg tggtcacaag tgcatccctc ccagtgcatc aacaaaagca 8700

 gaccttatta aaatgatcaa agaggaacaa aagaaatatg aaactgaaga 8750

 aggagtgaat aaagctgctt ggcagaaaac agttaacaat aatcaacaaa 8800

 gtctctttca gcgtctggat tcaaaatcaa aggatatatc taaaatagct 8850

 gcagatatca cccaggcagt gtctctctcc caaggaaatg agagaaaaaa 8900

 ggtgatccag catattagag gaatgtataa agtagatttg agtgccagca 8950

 gacattggca ggaacttatt cagcagctga cacatgatag agcagtatgg 9000

 tatgacccca tctactatcc aacctcatgg cagttggatc caacagaagg 9050

 gccaaatcga gagaggagac gtttacagag atgttattta actattccaa 9100

 ataagtatct ccttagggat agacagaaat cagaagatgt tgtcaaacca 9150

 ccactctctt acctgtttga agacaaaact cattcttctt tctcttctac 9200

 tgtcaaagac aaagctgcaa gtgaatctat aagagtgaat cgaagatgca 9250

 tcagtgttgc accatctaga gagacagctg gtgaattgtt actaggtaaa 9300

 tgtggaatgt attttgtgga agataatgct tctgatacag ttgaaagttc 9350

 gagccttcag ggagagttgg aaccagcatc attttcctgg acatatgaag 9400

 aaattaaaga agttcacaag cgttggtggc aattgagaga taatgctgta 9450

 gaaatctttc taacaaatgg cagaacactc ctgttggcat ttgataacac 9500

 caaggttcgt gatgatgtat accacaatat actcacaaat aacctcccta 9550

 atcttctgga atatggtaac atcaccgctc tgacaaattt atggtatact 9600

 gggcaaatta ctaattttga atatttgact cacttaaaca aacatgctgg 9650

 ccgatccttc aatgatctca tgcagtatcc tgtgttccca tttatacttg 9700

 ctgactacgt tagtgagaca cttgacctca atgatctgtt gatatacaga 9750

 aatctctcta aacctatagc tgttcagtat aaagaaaaag aagatcgtta 9800

 tgtggacaca tacaagtact tggaggaaga gtaccgcaaa ggagccagag 9850

 aagatgaccc catgcctccc gtgcagccct atcactatgg ctcccactat 9900

 tccaatagcg gcactgtgct tcacttcctg gtcaggatgc ctcctttcac 9950

 taaaatgttt ttagcctatc aagatcaaag ttttgacatt ccagacagaa 10000

 cttttcattc tacaaataca acttggcgac tctcatcttt tgaatctatg 10050

 actgatgtga aagaacttat cccagagttt ttctatcttc cagagttcct 10100

 agttaaccgt gaaggttttg attttggtgt gcgtcagaat ggtgaacggg 10150

 ttaatcacgt caaccttccc ccttgggcgc gtaatgatcc tcgtcttttt 10200

 atcctcatcc atcggcaggc tctagagtct gactacgtgt cgcagaacat 10250

 ctgtcagtgg attgacttgg tgtttgggta taagcaaaag gggaaggctt 10300

 ctgttcaagc gatcaatgtt tttcatcctg ctacatattt tggaatggat 10350

 gtctctgcag ttgaagatcc agttcagaga cgagcgctag aaaccatgat 10400

 aaaaacctac gggcagactc cccgtcagct gttccacatg gcccatgtga 10450

 gcagacctgg agccaagctc aatattgaag gagagcttcc agctgctgtg 10500

 gggttgctag tgcagtttgc tttcagggag acccgagaac aggtcaaaga 10550

 aatcacctat ccgagtcctt tgtcatggat aaaaggcttg aaatgggggg 10600

 aatacgtggg ttcccccagt gctccagtac ctgtggtctg cttcagccag 10650

 ccccacggag aaagatttgg ctctctccag gctctgccca ccagagcaat 10700

 ctgtggtttg tcacggaatt tctgtcttgt gatgacatat agcaaggaac 10750

 aaggtgtgag aagcatgaac agtacggaca ttcagtggtc agccatcctg 10800

 agctggggat atgctgataa tattttaagg ttgaagagta aacaaagtga 10850

 gcctccagta aactttattc aaagttcaca acagtaccag gtgactagtt 10900

 gtgcttgggt gcctgacagt tgccagctgt ttactggaag caaatgcggt 10950

 gtcatcacag cctacacaaa cagatttaca agcagcacgc catcagaaat 11000

 agaaatggag actcaaatac atctctatgg tcacacagaa gagataacca 11050

 gcttatttgt ttgcaaacca tacagtatac tgataagtgt gagcagagac 11100

 ggaacctgca tcatatggga tttaaacagg ttatgctatg tacaaagtct 11150

 ggcgggacac aaaagccctg tcacagctgt ctctgccagt gaaacctcag 11200

 gtgatattgc tactgtgtgt gattcagctg gcggaggcag tgacctcaga 11250

 ctctggacgg tgaacgggga tctcgttgga catgtccact gcagggagat 11300

 catctgttcc gtggctttct ccaaccagcc tgagggagta tctatcaatg 11350

 taatcgctgg gggattagaa aatggaattg taaggttatg gagcacatgg 11400

 gacttaaagc ctgtgagaga aattacattt cccaaatcaa ataagcccat 11450

 catcagcctt acattttctt gtgatggcca ccatttgtac acagcaaaca 11500

 gtgatgggac cgtgattgcc tggtgtcgga aggaccagca gcgcttgaaa 11550

 cagccaatgt tctattcctt ccttagcagc tatgcagccg ggtgaatgcg 11600

 aatgaacttc acgttctcca aagcacttta actccaaact agatttgttg 11650

 acttcaccag ttttaggagg ttgaacctaa agaaatggat gactggacaa 11700

 accatccaaa taatgataaa gtctattcat ctgcacaaaa ttctgaagag 11750

 tcacatgatc ctaagaggaa agttctgttc tattttagtg ataatctgga 11800

 agattgtgtc aatatgcact agccaacaag ttttaagcct cgcatggtac 11850

 attaaaatga tattcttaaa attttttccc accaaggtat tccaaagaaa 11900

 atattaaggt ctcccctttt tctatgattc caaaaggacc agtagaattt 11950

 aaattggttg gttgatngtt tatataaaac acactaaaat tatattttaa 12000

 aagtttantg ccntgaaata ctcctcccac cacacacaca tgctccaaaa 12050

 gaggaaagaa aaaaagataa tttttaggac ttgataattg ctttctttga 12100

 gaagcaaatt attcagtagg tgcctctgta ccaaatattt tatggaatat 12150

 ctaaatacta aaataaacta tgaatgaatc tcaaaattag gcagtttttg 12200

 ccagttgctt tcttagctca aaggagaacc agaatttttt tgacagccac 12250

 aaacaagaat acaggtatct tggatttcag acacattctg tttcttcata 12300

 aaaattttac ttaaaatctg taacgctaga tattgactat ccttagttga 12350

 gtcactgagg tttaaacaca atggtaagtc ttaaagtctg ctatttacag 12400

 agcattgaat ctgtaccaat ttgcaataga aagccttcag tatgcaagaa 12450

 gtttgcatgg gtattaagaa cacagcctaa ataaggcatt tgatctaatc 12500

 tgcaggaaga attttcttcc ccaaaacaga attataaaag cttactttaa 12550

 acaggaggca gaataattct tttaggaaac catttcattc tgtttctact 12600

 aacctatacc atctgagaat tcctaaacat cttggagccg tctgtctctc 12650

 ccatatgatg gctgtctgta tatttttact tggggtgctg ctttattggc 12700

 tttgaaaaca ctgtcagata agctcagtaa tatgttacca tgggataaaa 12750

 atatgtatcc ctgcctaaga ataacttgtg catttgttat ggaaatttaa 12800

 ttcatatggt gtttacagta ctacttttgt aacttccaga ctttctaaaa 12850

 cattctgctt aaaaaccata taaaatataa ttccaaagtc tctgctgtca 12900

 agatagattc gagagaaagc acgtggccat gtatgcttta accttaaact 12950

 gcatacacat gtagtgatac ctaggctgca tttagatcac cgtgtgctca 13000

 ggccaggtgt gaatcctgag gtccatggag gtgcagagat gagattactc 13050

 ctattcacgt tgaagtgatt tgctttgtta acaaaaaatt gcagctattg 13100

 tctagctttc atttttttac tgagaacttt aaattagtcc cctattagaa 13150

 tagggttgct actcatcttt ttttaaaaac cgaatttcat catttatcta 13200

 aagagaaaat atgcagaata actggtcttg ttaagagtgc aatattatat 13250

 ttttatgtaa aaataaaaat taatttgggg ggattattta ttcagcatga 13300

 aacctaatat gtatatgttt gaaatacttc ataatgtgca tgttgtagca 13350

 aacatttctg taaattatca caagctctgt tacctttata tacgctgcct 13400

 cttcaatttg gaaataaatt tcataaaaaa aaaaaaaaaa aaaaaaaaa 13449

<210> 908
<211> 2000
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 11967, 12008, 12013
<223> Unknown amino acid

<400> 908
 Met Ser Thr Asp Ser Asn Ser Leu Ala Arg Glu Phe Leu Thr Asp
   1               5                  10                  15

 Val Asn Arg Leu Cys Asn Ala Val Val Gln Arg Val Glu Ala Arg
                  20                  25                  30

 Glu Glu Glu Glu Glu Glu Thr His Met Ala Thr Leu Gly Gln Tyr
                  35                  40                  45

 Leu Val His Gly Arg Gly Phe Leu Leu Leu Thr Lys Leu Asn Ser
                  50                  55                  60

 Ile Ile Asp Gln Ala Leu Thr Cys Arg Glu Glu Leu Leu Thr Leu
                  65                  70                  75

 Leu Leu Ser Leu Leu Pro Leu Val Trp Lys Ile Pro Val Gln Glu
                  80                  85                  90

 Glu Lys Ala Thr Asp Phe Asn Leu Pro Leu Ser Ala Asp Ile Ile
                  95                 100                 105

 Leu Thr Lys Glu Lys Asn Ser Ser Ser Gln Arg Ser Thr Gln Glu
                 110                 115                 120

 Lys Leu His Leu Glu Gly Ser Ala Leu Ser Ser Gln Val Ser Ala
                 125                 130                 135

 Lys Val Asn Val Phe Arg Lys Ser Arg Arg Gln Arg Lys Ile Thr
                 140                 145                 150

 His Arg Tyr Ser Val Arg Asp Ala Arg Lys Thr Gln Leu Ser Thr
                 155                 160                 165

 Ser Asp Ser Glu Ala Asn Ser Asp Glu Lys Gly Ile Ala Met Asn
                 170                 175                 180

 Lys His Arg Arg Pro His Leu Leu His His Phe Leu Thr Ser Phe
                 185                 190                 195

 Pro Lys Gln Asp His Pro Lys Ala Lys Leu Asp Arg Leu Ala Thr
                 200                 205                 210

 Lys Glu Gln Thr Pro Pro Asp Ala Met Ala Leu Glu Asn Ser Arg
                 215                 220                 225

 Glu Ile Ile Pro Arg Gln Gly Ser Asn Thr Asp Ile Leu Ser Glu
                 230                 235                 240

 Pro Ala Ala Leu Ser Val Ile Ser Asn Met Asn Asn Ser Pro Phe
                 245                 250                 255

 Asp Leu Cys His Val Leu Leu Ser Leu Leu Glu Lys Val Cys Lys
                 260                 265                 270

 Phe Asp Val Thr Leu Asn His Asn Ser Pro Leu Ala Ala Ser Val
                 275                 280                 285

 Val Pro Thr Leu Thr Glu Phe Leu Ala Gly Phe Gly Asp Cys Cys
                 290                 295                 300

 Ser Leu Ser Asp Asn Leu Glu Ser Arg Val Val Ser Ala Gly Trp
                 305                 310                 315

 Thr Glu Glu Pro Val Ala Leu Ile Gln Arg Met Leu Phe Arg Thr
                 320                 325                 330

 Val Leu His Leu Leu Ser Val Asp Val Ser Thr Ala Glu Met Met
                 335                 340                 345

 Pro Glu Asn Leu Arg Lys Asn Leu Thr Glu Leu Leu Arg Ala Ala
                 350                 355                 360

 Leu Lys Ile Arg Ile Cys Leu Glu Lys Gln Pro Asp Pro Phe Ala
                 365                 370                 375

 Pro Arg Gln Lys Lys Thr Leu Gln Glu Val Gln Glu Asp Phe Val
                 380                 385                 390

 Phe Ser Lys Tyr Arg His Arg Ala Leu Leu Leu Pro Glu Leu Leu
                 395                 400                 405

 Glu Gly Val Leu Gln Ile Leu Ile Cys Cys Leu Gln Ser Ala Ala
                 410                 415                 420

 Ser Asn Pro Phe Tyr Phe Ser Gln Ala Met Asp Leu Val Gln Glu
                 425                 430                 435

 Phe Ile Gln His His Gly Phe Asn Leu Phe Glu Thr Ala Val Leu
                 440                 445                 450

 Gln Met Glu Trp Leu Val Leu Arg Asp Gly Val Pro Pro Glu Ala
                 455                 460                 465

 Ser Glu His Leu Lys Ala Leu Ile Asn Ser Val Met Lys Ile Met
                 470                 475                 480

 Ser Thr Val Lys Lys Val Lys Ser Glu Gln Leu His His Ser Met
                 485                 490                 495

 Cys Thr Arg Lys Arg His Arg Arg Cys Glu Tyr Ser His Phe Met
                 500                 505                 510

 His His His Arg Asp Leu Ser Gly Leu Leu Val Ser Ala Phe Lys
                 515                 520                 525

 Asn Gln Val Ser Lys Asn Pro Phe Glu Glu Thr Ala Asp Gly Asp
                 530                 535                 540

 Val Tyr Tyr Pro Glu Arg Cys Cys Cys Ile Ala Val Cys Ala His
                 545                 550                 555

 Gln Cys Leu Arg Leu Leu Gln Gln Ala Ser Leu Ser Ser Thr Cys
                 560                 565                 570

 Val Gln Ile Leu Ser Gly Val His Asn Ile Gly Ile Cys Cys Cys
                 575                 580                 585

 Met Asp Pro Lys Ser Val Ile Ile Pro Leu Leu His Ala Phe Lys
                 590                 595                 600

 Leu Pro Ala Leu Lys Asn Phe Gln Gln His Ile Leu Asn Ile Leu
                 605                 610                 615

 Asn Lys Leu Ile Leu Asp Gln Leu Gly Gly Ala Glu Ile Ser Pro
                 620                 625                 630

 Lys Ile Lys Lys Ala Ala Cys Asn Ile Cys Thr Val Asp Ser Asp
                 635                 640                 645

 Gln Leu Ala Gln Leu Glu Glu Thr Leu Gln Gly Asn Leu Cys Asp
                 650                 655                 660

 Ala Glu Leu Ser Ser Ser Leu Ser Ser Pro Ser Tyr Arg Phe Gln
                 665                 670                 675

 Gly Ile Leu Pro Ser Ser Gly Ser Glu Asp Leu Leu Trp Lys Trp
                 680                 685                 690

 Asp Ala Leu Lys Ala Tyr Gln Asn Phe Val Phe Glu Glu Asp Arg
                 695                 700                 705

 Leu His Ser Ile Gln Ile Ala Asn His Ile Cys Asn Leu Ile Gln
                 710                 715                 720

 Lys Gly Asn Ile Val Val Gln Trp Lys Leu Tyr Asn Tyr Ile Phe
                 725                 730                 735

 Asn Pro Val Leu Gln Arg Gly Val Glu Leu Ala His His Cys Gln
                 740                 745                 750

 His Leu Ser Val Thr Ser Ala Gln Ser His Val Cys Ser His His
                 755                 760                 765

 Asn Gln Cys Leu Pro Gln Asp Val Leu Gln Ile Tyr Val Lys Thr
                 770                 775                 780

 Leu Pro Ile Leu Leu Lys Ser Arg Val Ile Arg Asp Leu Phe Leu
                 785                 790                 795

 Ser Cys Asn Gly Val Ser Gln Ile Ile Glu Leu Asn Cys Leu Asn
                 800                 805                 810

 Gly Ile Arg Ser His Ser Leu Lys Ala Phe Glu Thr Leu Ile Ile
                 815                 820                 825

 Ser Leu Gly Glu Gln Gln Lys Asp Ala Ser Val Pro Asp Ile Asp
                 830                 835                 840

 Gly Ile Asp Ile Glu Gln Lys Glu Leu Ser Ser Val His Val Gly
                 845                 850                 855

 Thr Ser Phe His His Gln Gln Ala Tyr Ser Asp Ser Pro Gln Ser
                 860                 865                 870

 Leu Ser Lys Phe Tyr Ala Gly Leu Lys Glu Ala Tyr Pro Lys Arg
                 875                 880                 885

 Arg Lys Thr Val Asn Gln Asp Val His Ile Asn Thr Ile Asn Leu
                 890                 895                 900

 Phe Leu Cys Val Ala Phe Leu Cys Val Ser Lys Glu Ala Glu Ser
                 905                 910                 915

 Asp Arg Glu Ser Ala Asn Asp Ser Glu Asp Thr Ser Gly Tyr Asp
                 920                 925                 930

 Ser Thr Ala Ser Glu Pro Leu Ser His Met Leu Pro Cys Ile Ser
                 935                 940                 945

 Leu Glu Ser Leu Val Leu Pro Ser Pro Glu His Met His Gln Ala
                 950                 955                 960

 Ala Asp Ile Trp Ser Met Cys Arg Trp Ile Tyr Met Leu Ser Ser
                 965                 970                 975

 Val Phe Gln Lys Gln Phe Tyr Arg Leu Gly Gly Phe Arg Val Cys
                 980                 985                 990

 His Lys Leu Ile Phe Met Ile Ile Gln Lys Leu Phe Arg Ser His
                 995                1000                1005

 Lys Glu Glu Gln Gly Lys Lys Glu Gly Asp Thr Ser Val Asn Glu
                1010                1015                1020

 Asn Gln Asp Leu Asn Arg Ile Ser Gln Pro Lys Arg Thr Met Lys
                1025                1030                1035

 Glu Asp Leu Leu Ser Leu Ala Ile Lys Ser Asp Pro Ile Pro Ser
                1040                1045                1050

 Glu Leu Gly Ser Leu Lys Lys Ser Ala Asp Ser Leu Gly Lys Leu
                1055                1060                1065

 Glu Leu Gln His Ile Ser Ser Ile Asn Val Glu Glu Val Ser Ala
                1070                1075                1080

 Thr Glu Ala Ala Pro Glu Glu Ala Lys Leu Phe Thr Ser Gln Glu
                1085                1090                1095

 Ser Glu Thr Ser Leu Gln Ser Ile Arg Leu Leu Glu Ala Leu Leu
                1100                1105                1110

 Ala Ile Cys Leu His Gly Ala Arg Thr Ser Gln Gln Lys Met Glu
                1115                1120                1125

 Leu Glu Leu Pro Asn Gln Asn Leu Ser Val Glu Ser Ile Leu Phe
                1130                1135                1140

 Glu Met Arg Asp His Leu Ser Gln Ser Lys Val Ile Glu Thr Gln
                1145                1150                1155

 Leu Ala Lys Pro Leu Phe Asp Ala Leu Leu Arg Val Ala Leu Gly
                1160                1165                1170

 Asn Tyr Ser Ala Asp Phe Glu His Asn Asp Ala Met Thr Glu Lys
                1175                1180                1185

 Ser His Gln Ser Ala Glu Glu Leu Ser Ser Gln Pro Gly Asp Phe
                1190                1195                1200

 Ser Glu Glu Ala Glu Asp Ser Gln Cys Cys Ser Phe Lys Leu Leu
                1205                1210                1215

 Val Glu Glu Glu Gly Tyr Glu Ala Asp Ser Glu Ser Asn Pro Glu
                1220                1225                1230

 Asp Gly Glu Thr Gln Asp Asp Gly Val Asp Leu Lys Ser Glu Thr
                1235                1240                1245

 Glu Gly Phe Ser Ala Ser Ser Ser Pro Asn Asp Leu Leu Glu Asn
                1250                1255                1260

 Leu Thr Gln Gly Glu Ile Ile Tyr Pro Glu Ile Cys Met Leu Glu
                1265                1270                1275

 Leu Asn Leu Leu Ser Ala Ser Lys Ala Lys Leu Asp Val Leu Ala
                1280                1285                1290

 His Val Phe Glu Ser Phe Leu Lys Ile Ile Arg Gln Lys Glu Lys
                1295                1300                1305

 Asn Val Phe Leu Leu Met Gln Gln Gly Thr Val Lys Asn Leu Leu
                1310                1315                1320

 Gly Gly Phe Leu Ser Ile Leu Thr Gln Asp Asp Ser Asp Phe Gln
                1325                1330                1335

 Ala Cys Gln Arg Val Leu Val Asp Leu Leu Val Ser Leu Met Ser
                1340                1345                1350

 Ser Arg Thr Cys Ser Glu Glu Leu Thr Leu Leu Leu Arg Ile Phe
                1355                1360                1365

 Leu Glu Lys Ser Pro Cys Thr Lys Ile Leu Leu Leu Gly Ile Leu
                1370                1375                1380

 Lys Ile Ile Glu Ser Asp Thr Thr Met Ser Pro Ser Gln Tyr Leu
                1385                1390                1395

 Thr Phe Pro Leu Leu His Ala Pro Asn Leu Ser Asn Gly Val Ser
                1400                1405                1410

 Ser Gln Lys Tyr Pro Gly Ile Leu Asn Ser Lys Ala Met Gly Leu
                1415                1420                1425

 Leu Arg Arg Ala Arg Val Ser Arg Ser Lys Lys Glu Ala Asp Arg
                1430                1435                1440

 Glu Ser Phe Pro His Arg Leu Leu Ser Ser Trp His Ile Ala Pro
                1445                1450                1455

 Val His Leu Pro Leu Leu Gly Gln Asn Cys Trp Pro His Leu Ser
                1460                1465                1470

 Glu Gly Phe Ser Val Ser Leu Trp Phe Asn Val Glu Cys Ile His
                1475                1480                1485

 Glu Ala Glu Ser Thr Thr Glu Lys Gly Lys Lys Ile Lys Lys Arg
                1490                1495                1500

 Asn Lys Ser Leu Ile Leu Pro Asp Ser Ser Phe Asp Gly Thr Glu
                1505                1510                1515

 Ser Asp Arg Pro Glu Gly Ala Glu Tyr Ile Asn Pro Gly Glu Arg
                1520                1525                1530

 Leu Ile Glu Glu Gly Cys Ile His Ile Ile Ser Leu Gly Ser Lys
                1535                1540                1545

 Ala Leu Met Ile Gln Val Trp Ala Asp Pro His Asn Ala Thr Leu
                1550                1555                1560

 Ile Phe Arg Val Cys Met Asp Ser Asn Asp Asp Met Lys Ala Val
                1565                1570                1575

 Leu Leu Ala Gln Val Glu Ser Gln Glu Asn Ile Phe Leu Pro Ser
                1580                1585                1590

 Lys Trp Gln His Leu Val Leu Thr Tyr Leu Gln Gln Pro Gln Gly
                1595                1600                1605

 Lys Arg Arg Ile His Gly Lys Ile Ser Ile Trp Val Ser Gly Gln
                1610                1615                1620

 Arg Lys Pro Asp Val Thr Leu Asp Phe Met Leu Pro Arg Lys Thr
                1625                1630                1635

 Ser Leu Ser Ser Asp Ser Asn Lys Thr Phe Cys Met Ile Gly His
                1640                1645                1650

 Cys Leu Ser Ser Gln Glu Glu Phe Leu Gln Leu Ala Gly Lys Trp
                1655                1660                1665

 Asp Leu Gly Asn Leu Leu Leu Phe Asn Gly Ala Lys Val Gly Ser
                1670                1675                1680

 Gln Glu Ala Phe Tyr Leu Tyr Ala Cys Gly Pro Asn His Thr Ser
                1685                1690                1695

 Val Met Pro Cys Lys Tyr Gly Lys Pro Val Asn Asp Tyr Ser Lys
                1700                1705                1710

 Tyr Ile Asn Lys Glu Ile Leu Arg Cys Glu Gln Ile Arg Glu Leu
                1715                1720                1725

 Phe Met Thr Lys Lys Asp Val Asp Ile Gly Leu Leu Ile Glu Ser
                1730                1735                1740

 Leu Ser Val Val Tyr Thr Thr Tyr Cys Pro Ala Gln Tyr Thr Ile
                1745                1750                1755

 Tyr Glu Pro Val Ile Arg Leu Lys Gly Gln Met Lys Thr Gln Leu
                1760                1765                1770

 Ser Gln Arg Pro Phe Ser Ser Lys Glu Val Gln Ser Ile Leu Leu
                1775                1780                1785

 Glu Pro His His Leu Lys Asn Leu Gln Pro Thr Glu Tyr Lys Thr
                1790                1795                1800

 Ile Gln Gly Ile Leu His Glu Ile Gly Gly Thr Gly Ile Phe Val
                1805                1810                1815

 Phe Leu Phe Ala Arg Val Val Glu Leu Ser Ser Cys Glu Glu Thr
                1820                1825                1830

 Gln Ala Leu Ala Leu Arg Val Ile Leu Ser Leu Ile Lys Tyr Asn
                1835                1840                1845

 Gln Gln Arg Val His Glu Leu Glu Asn Cys Asn Gly Leu Ser Met
                1850                1855                1860

 Ile His Gln Val Leu Ile Lys Gln Lys Cys Ile Val Gly Phe Tyr
                1865                1870                1875

 Ile Leu Lys Thr Leu Leu Glu Gly Cys Cys Gly Glu Asp Ile Ile
                1880                1885                1890

 Tyr Met Asn Glu Asn Gly Glu Phe Lys Leu Asp Val Asp Ser Asn
                1895                1900                1905

 Ala Ile Ile Gln Asp Val Lys Leu Leu Glu Glu Leu Leu Leu Asp
                1910                1915                1920

 Trp Lys Ile Trp Ser Lys Ala Glu Gln Gly Val Trp Glu Thr Leu
                1925                1930                1935

 Leu Ala Ala Leu Glu Val Leu Ile Arg Ala Asp His His Gln Gln
                1940                1945                1950

 Met Phe Asn Ile Lys Gln Leu Leu Lys Ala Gln Val Val His His
                1955                1960                1965

 Phe Leu Leu Thr Cys Gln Val Leu Gln Glu Tyr Lys Glu Gly Gln
                1970                1975                1980

 Leu Thr Pro Met Pro Arg Glu Val Cys Arg Ser Phe Val Lys Ile
                1985                1990                1995

 Ile Ala Glu Val Leu
                2000

<210> 909
<211> 4859
<212> DNA
<213> Homo sapien

<400> 909
 cacgttgggt gacataatgg ggttttttta attatagatt cacactgcat 50

 ttattcatca cccctgtcct ctcatccata actcaaattt actaccagca 100

 acacaaaata caaagatgtg tccagtttca ctacagctct tcgcgtttac 150

 aagtgtcgag cgcttgcttt cggaacgccc ttgtgattgg ccgagccaat 200

 gccagtgaca tcaaccaact tacttttgat tggaaggctg gttgctggga 250

 ctgtagcgtt tgcaggaagt cacttaactg tttgggagct ggaaaaccga 300

 agctgaagtt ctcttttgcc ataggaacga gcgcaactga ctaggaaaga 350

 tgtgtcccaa agctccgcaa gctggaacgt gagccaggag gcccggaccg 400

 gccacgggac cgcgaggcac tccgaaagtg tgcggctgcc ccttccctgc 450

 ctcccagctg ttaccctttt aaatgtcagt gttcgaggct gtaggggtag 500

 cacgaggcag cgaaacggaa cagtcggatt ggccgcacgc ctcagttcta 550

 gacgcacctc tccaccgaag ccgttctgac tggcaggggg agaaagtaaa 600

 cagagttgaa tcaccctccc cactggccaa ttggaggggg tttggtttgt 650

 gacgtgatgg gattctgcga aattgttact gagcaagaga atgccggaac 700

 gtgcggaccg gccggagcag gggttcagaa gccgtcagtg gactcgggaa 750

 aaagtgtctc ttagacctgg cgctcggcgg ggccctcgcc acccgcgtcg 800

 gggtgatcgg gtgaatgtcc tggggctttg gctcgacggc gaggcggccg 850

 agggcgtgca cctctcttgc agtttcctct cccagcgcct cgggggcgtt 900

 ttcagtcgaa taaacttgcg accgccacgt gtggcatctt tccaagggag 950

 ccggctcaga ggggccggcg cgcccgtcgg gggatcgcgg ccggcgcggg 1000

 gcaggggcgg cggctagagg cggcggcgcg gcggagcccg gggccgtgga 1050

 tgctgcgtgc ggaggcgctg ccggttacgt aaagatgagg ggctgaggtc 1100

 gcctcggcgc tcctgcgagt cggaagcgcc ccgcgccccc gcccccttgg 1150

 ccgccgcgcc gtgccgggcg ggcgggtcgt cgtccgaggc cagggagggc 1200

 gagccgaacc tccgcagcca ccgccaagtt tgtccgcgcc gcctgggctg 1250

 ccgtcgcccg caccatgtcc gcggccgcct acatggactt cgtggctgcc 1300

 cagtgtctgg tttccatttc gaaccgcgct gcggtgccgg agcatggggt 1350

 cgctccggac gccgagcggc tgcgactacc tgagcgcgag gtgaccaagg 1400

 agcacggtga cccgggggac acctggaagg attactgcac actggtcacc 1450

 atcgccaaga gcttgttgga cctgaacaag taccgaccca tccagacccc 1500

 ctccgtgtgc agcgacagtc tggaaagtcc agatgaggat atgggatccg 1550

 acagcgacgt gaccaccgaa tctgggtcga gtccttccca cagcccggag 1600

 gagagacagg atcctggcag cgcgcccagc ccgctctccc tcctccatcc 1650

 tggagtggct gcgaagggga aacacgcctc cgaaaagagg cacaagtgcc 1700

 cctacagtgg ctgtgggaaa gtctatggaa aatcctccca tctcaaagcc 1750

 cattacagag tgcatacagg tgaacggccc ttcccctgca cgtggccaga 1800

 ctgccttaaa aagttctccc gctcagacga gctgacccgc cactaccgga 1850

 cccacactgg ggaaaagcag ttccgctgtc cgctgtgtga gaagcgcttc 1900

 atgaggagtg accacctcac aaagcacgcc cggcggcaca ccgagttcca 1950

 ccccagcatg atcaagcgat cgaaaaaggc gctggccaac gctttgtgag 2000

 gtgctgcccg tggaagccag ggagggatgg accccgaaag gacaaaagta 2050

 ctcccaggaa acagacgcgt gaaaactgag ccccagaaga ggcacacttg 2100

 acggcacagg aagtcactgc tctttggtca atattctgat tttcctctcc 2150

 ctgcattgtt tttaaaaagc acattgtagc ctaagatcaa agtcaacaac 2200

 actcggtccc cttgaagagg caactctctg aacccgtctc tgactgttgg 2250

 agggaaggca aatgcttttg ggttttttgg tttttgtttt tgtttttttt 2300

 tctcctttta tttttttgcg ggggagggta gggagtgggt gggggggagg 2350

 gggtaaggcc aagactgggt agattttaaa gattcaacac tggtgtacat 2400

 atgtccgctg ggtgagttga cctgtggcct cgcacagtga ttctaggccc 2450

 tttatgcttg ctgtctctca gaattgtttt cttacctttt aatgtaatga 2500

 cgagtgtgct tcagtttgtt tagcaaaacc actctcttga atcacgttaa 2550

 cttttgagat taaaaaaaaa aacgccatag cacagctgtc tttatgcaag 2600

 caagagcaca tctactccag catgatctgt catctaaaga cttgaaaaca 2650

 aaaaacagtt acttatagtc aatgggtaag cagagtctga atttatacta 2700

 atcaagacaa acctttgaaa ggttacacta agtacagaac ttttaaacct 2750

 tgctttgtat gagttgtact ttttgaacat aagctgcact tttattttct 2800

 aatgcagagg atgaataagt taaatacatg ctttgaggat agaagcagat 2850

 gttctgtttg gcaccacgtt ataatctgct tattttacaa tatacacgtt 2900

 tccctaagaa atcatgcgca gagatgtgag ggcagaatat acacaacaga 2950

 tgctgaagga gaaggagggt agtgttttgc aaaagaaaaa gaaaagaacc 3000

 aacagaattt taactctatt aacttttcca aattttccta tgcttttagt 3050

 taacatcatt attgtatcct aatgccacta ggggagagag cttttgactc 3100

 tgttgggttt tatttgaatg tgtgcataac agtaatgaga tctggaaaca 3150

 cctatttttt ggggaaaaag gtttgttggt ctccttcctg tgttcctaca 3200

 aaactcccac tctcaggtgc aagagttatg tagaaggaaa gggagctgaa 3250

 ataggaacag aaaaatcaac ccctataact agtgaacacc aagggaaaat 3300

 accacaatga tttcagagga gactctgcaa aatcgtccct tgtggagaat 3350

 gcaggcaaca tggaatacta cgaatgaaat cacatcactg tatcttttac 3400

 atcaatagcc tcaccactaa tatatcttgt atctaggtgt ctataatggc 3450

 tgaaaccact acatccatct atgccattta cctgaaaact taactgtggc 3500

 ctttatgagg ccagaaaagt gaactgagtt ttgtagttaa gacctcaaat 3550

 gaggggagtc agcagtgatc atgggggaaa tgtttacatt ttttttttct 3600

 tcagaagtaa cgctttctga tgattttatc tgatatttaa aacagggagc 3650

 tatggtgcac tctagtttat acttgcgctc tgaaatgtgt aaacataggg 3700

 tgcctaccta tttcacctga cccatactcg tttctgattc agaatcagtg 3750

 tgggctcctg cagtgggcgc gggtcacggc tgactccaac ttccaataca 3800

 acagccatca ctagcacagt gtttttttgt ttaaccaacg tagtgttatt 3850

 agtagttcta taaagagaac tgcttttaac attagggact gggagcagtc 3900

 catgggataa aaaggaaagt gttttctcac gagaaaacat gtcaggaaaa 3950

 ataaagaaca ctttctacct ctgtttcaga tttttgaaac acttatttta 4000

 aaccaaattt taatttctgt gtccaaaata agttttaagg acatctgttc 4050

 ttccatacga aataggttag gctgcctatt tctcactgag ctcatggaat 4100

 ggttctgctt atgatactct gcacgctgcc ttttagtgag tgaggagttt 4150

 ggggttgcct agcacttgct aacttgtaaa aagtcatctt tccctcacag 4200

 aaagaaacga aagaaagcaa agcaaagtca gtgaaagaca atctttatag 4250

 tttcaggagt aaatctaaat gtggcttttg tcaagcactt agatggatat 4300

 aaatgcagca acttgtttta aaaaaatgca catttacttc ccaaaaaagt 4350

 tgttacttgc cttttcaagt gtgacaaact cacatttgat attctcttat 4400

 atgttatagt aatgtaacgt ataaactcaa gcctttttat tctttgtgat 4450

 taaatcctgt tttaaaatgt cacaaaacag gaaccagcat tctaattaga 4500

 tttactatat caagatatgg ttcaaatagg actactagag ttcattgaac 4550

 actaaaacta tgaaacaatt actttttata ttaaaaagac catggattta 4600

 acttatgaaa atccaaatgc aggatagtaa tttttgttta cttttttaac 4650

 caaactgaat ttttgaaaga ctattgcagg tgtttaaaaa gaaagaaaag 4700

 ttgttttatc taatactgta agtagttgtc atattctgga aaatttaata 4750

 gttttagagt taagatatct cctctctttg gttagggaag aagaaagccc 4800

 ttcaccattg tggaatgatg ccctggcttt aaggtttagc tccacatcat 4850

 gcttctctt 4859

<210> 910
<211> 244
<212> PRT
<213> Homo sapien

<400> 910
 Met Ser Ala Ala Ala Tyr Met Asp Phe Val Ala Ala Gln Cys Leu
   1               5                  10                  15

 Val Ser Ile Ser Asn Arg Ala Ala Val Pro Glu His Gly Val Ala
                  20                  25                  30

 Pro Asp Ala Glu Arg Leu Arg Leu Pro Glu Arg Glu Val Thr Lys
                  35                  40                  45

 Glu His Gly Asp Pro Gly Asp Thr Trp Lys Asp Tyr Cys Thr Leu
                  50                  55                  60

 Val Thr Ile Ala Lys Ser Leu Leu Asp Leu Asn Lys Tyr Arg Pro
                  65                  70                  75

 Ile Gln Thr Pro Ser Val Cys Ser Asp Ser Leu Glu Ser Pro Asp
                  80                  85                  90

 Glu Asp Met Gly Ser Asp Ser Asp Val Thr Thr Glu Ser Gly Ser
                  95                 100                 105

 Ser Pro Ser His Ser Pro Glu Glu Arg Gln Asp Pro Gly Ser Ala
                 110                 115                 120

 Pro Ser Pro Leu Ser Leu Leu His Pro Gly Val Ala Ala Lys Gly
                 125                 130                 135

 Lys His Ala Ser Glu Lys Arg His Lys Cys Pro Tyr Ser Gly Cys
                 140                 145                 150

 Gly Lys Val Tyr Gly Lys Ser Ser His Leu Lys Ala His Tyr Arg
                 155                 160                 165

 Val His Thr Gly Glu Arg Pro Phe Pro Cys Thr Trp Pro Asp Cys
                 170                 175                 180

 Leu Lys Lys Phe Ser Arg Ser Asp Glu Leu Thr Arg His Tyr Arg
                 185                 190                 195

 Thr His Thr Gly Glu Lys Gln Phe Arg Cys Pro Leu Cys Glu Lys
                 200                 205                 210

 Arg Phe Met Arg Ser Asp His Leu Thr Lys His Ala Arg Arg His
                 215                 220                 225

 Thr Glu Phe His Pro Ser Met Ile Lys Arg Ser Lys Lys Ala Leu
                 230                 235                 240

 Ala Asn Ala Leu


<210> 911
<211> 4859
<212> DNA
<213> Homo sapien

<400> 911
 cacgttgggt gacataatgg ggttttttta attatagatt cacactgcat 50

 ttattcatca cccctgtcct ctcatccata actcaaattt actaccagca 100

 acacaaaata caaagatgtg tccagtttca ctacagctct tcgcgtttac 150

 aagtgtcgag cgcttgcttt cggaacgccc ttgtgattgg ccgagccaat 200

 gccagtgaca tcaaccaact tacttttgat tggaaggctg gttgctggga 250

 ctgtagcgtt tgcaggaagt cacttaactg tttgggagct ggaaaaccga 300

 agctgaagtt ctcttttgcc ataggaacga gcgcaactga ctaggaaaga 350

 tgtgtcccaa agctccgcaa gctggaacgt gagccaggag gcccggaccg 400

 gccacgggac cgcgaggcac tccgaaagtg tgcggctgcc ccttccctgc 450

 ctcccagctg ttaccctttt aaatgtcagt gttcgaggct gtaggggtag 500

 cacgaggcag cgaaacggaa cagtcggatt ggccgcacgc ctcagttcta 550

 gacgcacctc tccaccgaag ccgttctgac tggcaggggg agaaagtaaa 600

 cagagttgaa tcaccctccc cactggccaa ttggaggggg tttggtttgt 650

 gacgtgatgg gattctgcga aattgttact gagcaagaga atgccggaac 700

 gtgcggaccg gccggagcag gggttcagaa gccgtcagtg gactcgggaa 750

 aaagtgtctc ttagacctgg cgctcggcgg ggccctcgcc acccgcgtcg 800

 gggtgatcgg gtgaatgtcc tggggctttg gctcgacggc gaggcggccg 850

 agggcgtgca cctctcttgc agtttcctct cccagcgcct cgggggcgtt 900

 ttcagtcgaa taaacttgcg accgccacgt gtggcatctt tccaagggag 950

 ccggctcaga ggggccggcg cgcccgtcgg gggatcgcgg ccggcgcggg 1000

 gcaggggcgg cggctagagg cggcggcgcg gcggagcccg gggccgtgga 1050

 tgctgcgtgc ggaggcgctg ccggttacgt aaagatgagg ggctgaggtc 1100

 gcctcggcgc tcctgcgagt cggaagcgcc ccgcgccccc gcccccttgg 1150

 ccgccgcgcc gtgccgggcg ggcgggtcgt cgtccgaggc cagggagggc 1200

 gagccgaacc tccgcagcca ccgccaagtt tgtccgcgcc gcctgggctg 1250

 ccgtcgcccg caccatgtcc gcggccgcct acatggactt cgtggctgcc 1300

 cagtgtctgg tttccatttc gaaccgcgct gcggtgccgg agcatggggt 1350

 cgctccggac gccgagcggc tgcgactacc tgagcgcgag gtgaccaagg 1400

 agcacggtga cccgggggac acctggaagg attactgcac actggtcacc 1450

 atcgccaaga gcttgttgga cctgaacaag taccgaccca tccagacccc 1500

 ctccgtgtgc agcgacagtc tggaaagtcc agatgaggat atgggatccg 1550

 acagcgacgt gaccaccgaa tctgggtcga gtccttccca cagcccggag 1600

 gagagacagg atcctggcag cgcgcccagc ccgctctccc tcctccatcc 1650

 tggagtggct gcgaagggga aacacgcctc cgaaaagagg cacaagtgcc 1700

 cctacagtgg ctgtgggaaa gtctatggaa aatcctccca tctcaaagcc 1750

 cattacagag tgcatacagg tgaacggccc ttcccctgca cgtggccaga 1800

 ctgccttaaa aagttctccc gctcagacga gctgacccgc cactaccgga 1850

 cccacactgg ggaaaagcag ttccgctgtc cgctgtgtga gaagcgcttc 1900

 atgaggagtg accacctcac aaagcacgcc cggcggcaca ccgagttcca 1950

 ccccagcatg atcaagcgat cgaaaaaggc gctggccaac gctttgtgag 2000

 gtgctgcccg tggaagccag ggagggatgg accccgaaag gacaaaagta 2050

 ctcccaggaa acagacgcgt gaaaactgag ccccagaaga ggcacacttg 2100

 acggcacagg aagtcactgc tctttggtca atattctgat tttcctctcc 2150

 ctgcattgtt tttaaaaagc acattgtagc ctaagatcaa agtcaacaac 2200

 actcggtccc cttgaagagg caactctctg aacccgtctc tgactgttgg 2250

 agggaaggca aatgcttttg ggttttttgg tttttgtttt tgtttttttt 2300

 tctcctttta tttttttgcg ggggagggta gggagtgggt gggggggagg 2350

 gggtaaggcc aagactgggt agattttaaa gattcaacac tggtgtacat 2400

 atgtccgctg ggtgagttga cctgtggcct cgcacagtga ttctaggccc 2450

 tttatgcttg ctgtctctca gaattgtttt cttacctttt aatgtaatga 2500

 cgagtgtgct tcagtttgtt tagcaaaacc actctcttga atcacgttaa 2550

 cttttgagat taaaaaaaaa aacgccatag cacagctgtc tttatgcaag 2600

 caagagcaca tctactccag catgatctgt catctaaaga cttgaaaaca 2650

 aaaaacagtt acttatagtc aatgggtaag cagagtctga atttatacta 2700

 atcaagacaa acctttgaaa ggttacacta agtacagaac ttttaaacct 2750

 tgctttgtat gagttgtact ttttgaacat aagctgcact tttattttct 2800

 aatgcagagg atgaataagt taaatacatg ctttgaggat agaagcagat 2850

 gttctgtttg gcaccacgtt ataatctgct tattttacaa tatacacgtt 2900

 tccctaagaa atcatgcgca gagatgtgag ggcagaatat acacaacaga 2950

 tgctgaagga gaaggagggt agtgttttgc aaaagaaaaa gaaaagaacc 3000

 aacagaattt taactctatt aacttttcca aattttccta tgcttttagt 3050

 taacatcatt attgtatcct aatgccacta ggggagagag cttttgactc 3100

 tgttgggttt tatttgaatg tgtgcataac agtaatgaga tctggaaaca 3150

 cctatttttt ggggaaaaag gtttgttggt ctccttcctg tgttcctaca 3200

 aaactcccac tctcaggtgc aagagttatg tagaaggaaa gggagctgaa 3250

 ataggaacag aaaaatcaac ccctataact agtgaacacc aagggaaaat 3300

 accacaatga tttcagagga gactctgcaa aatcgtccct tgtggagaat 3350

 gcaggcaaca tggaatacta cgaatgaaat cacatcactg tatcttttac 3400

 atcaatagcc tcaccactaa tatatcttgt atctaggtgt ctataatggc 3450

 tgaaaccact acatccatct atgccattta cctgaaaact taactgtggc 3500

 ctttatgagg ccagaaaagt gaactgagtt ttgtagttaa gacctcaaat 3550

 gaggggagtc agcagtgatc atgggggaaa tgtttacatt ttttttttct 3600

 tcagaagtaa cgctttctga tgattttatc tgatatttaa aacagggagc 3650

 tatggtgcac tctagtttat acttgcgctc tgaaatgtgt aaacataggg 3700

 tgcctaccta tttcacctga cccatactcg tttctgattc agaatcagtg 3750

 tgggctcctg cagtgggcgc gggtcacggc tgactccaac ttccaataca 3800

 acagccatca ctagcacagt gtttttttgt ttaaccaacg tagtgttatt 3850

 agtagttcta taaagagaac tgcttttaac attagggact gggagcagtc 3900

 catgggataa aaaggaaagt gttttctcac gagaaaacat gtcaggaaaa 3950

 ataaagaaca ctttctacct ctgtttcaga tttttgaaac acttatttta 4000

 aaccaaattt taatttctgt gtccaaaata agttttaagg acatctgttc 4050

 ttccatacga aataggttag gctgcctatt tctcactgag ctcatggaat 4100

 ggttctgctt atgatactct gcacgctgcc ttttagtgag tgaggagttt 4150

 ggggttgcct agcacttgct aacttgtaaa aagtcatctt tccctcacag 4200

 aaagaaacga aagaaagcaa agcaaagtca gtgaaagaca atctttatag 4250

 tttcaggagt aaatctaaat gtggcttttg tcaagcactt agatggatat 4300

 aaatgcagca acttgtttta aaaaaatgca catttacttc ccaaaaaagt 4350

 tgttacttgc cttttcaagt gtgacaaact cacatttgat attctcttat 4400

 atgttatagt aatgtaacgt ataaactcaa gcctttttat tctttgtgat 4450

 taaatcctgt tttaaaatgt cacaaaacag gaaccagcat tctaattaga 4500

 tttactatat caagatatgg ttcaaatagg actactagag ttcattgaac 4550

 actaaaacta tgaaacaatt actttttata ttaaaaagac catggattta 4600

 acttatgaaa atccaaatgc aggatagtaa tttttgttta cttttttaac 4650

 caaactgaat ttttgaaaga ctattgcagg tgtttaaaaa gaaagaaaag 4700

 ttgttttatc taatactgta agtagttgtc atattctgga aaatttaata 4750

 gttttagagt taagatatct cctctctttg gttagggaag aagaaagccc 4800

 ttcaccattg tggaatgatg ccctggcttt aaggtttagc tccacatcat 4850

 gcttctctt 4859

<210> 912
<211> 244
<212> PRT
<213> Homo sapien

<400> 912
 Met Ser Ala Ala Ala Tyr Met Asp Phe Val Ala Ala Gln Cys Leu
   1               5                  10                  15

 Val Ser Ile Ser Asn Arg Ala Ala Val Pro Glu His Gly Val Ala
                  20                  25                  30

 Pro Asp Ala Glu Arg Leu Arg Leu Pro Glu Arg Glu Val Thr Lys
                  35                  40                  45

 Glu His Gly Asp Pro Gly Asp Thr Trp Lys Asp Tyr Cys Thr Leu
                  50                  55                  60

 Val Thr Ile Ala Lys Ser Leu Leu Asp Leu Asn Lys Tyr Arg Pro
                  65                  70                  75

 Ile Gln Thr Pro Ser Val Cys Ser Asp Ser Leu Glu Ser Pro Asp
                  80                  85                  90

 Glu Asp Met Gly Ser Asp Ser Asp Val Thr Thr Glu Ser Gly Ser
                  95                 100                 105

 Ser Pro Ser His Ser Pro Glu Glu Arg Gln Asp Pro Gly Ser Ala
                 110                 115                 120

 Pro Ser Pro Leu Ser Leu Leu His Pro Gly Val Ala Ala Lys Gly
                 125                 130                 135

 Lys His Ala Ser Glu Lys Arg His Lys Cys Pro Tyr Ser Gly Cys
                 140                 145                 150

 Gly Lys Val Tyr Gly Lys Ser Ser His Leu Lys Ala His Tyr Arg
                 155                 160                 165

 Val His Thr Gly Glu Arg Pro Phe Pro Cys Thr Trp Pro Asp Cys
                 170                 175                 180

 Leu Lys Lys Phe Ser Arg Ser Asp Glu Leu Thr Arg His Tyr Arg
                 185                 190                 195

 Thr His Thr Gly Glu Lys Gln Phe Arg Cys Pro Leu Cys Glu Lys
                 200                 205                 210

 Arg Phe Met Arg Ser Asp His Leu Thr Lys His Ala Arg Arg His
                 215                 220                 225

 Thr Glu Phe His Pro Ser Met Ile Lys Arg Ser Lys Lys Ala Leu
                 230                 235                 240

 Ala Asn Ala Leu


<210> 913
<211> 2967
<212> DNA
<213> Homo sapien

<400> 913
 tagctccgcg cgggggcttc ctcggctcct tgctgttgcc gccgccgcag 50

 ctgctgccgc ggttggtggg gttgggtgag aggaggagct gtcgcggacc 100

 ctgtagagtc ggtctctgtt gctctttttg cctgaggagt cttccatcct 150

 acgtcgagct ctgactcccg tgctgtcgag agggagtccc cggggacacc 200

 tcggcacgca gcggagatgc ctctttttgc caccaatccc ttcgatcagg 250

 atgttgagaa agcaaccagc gagatgaata ctgctgagga ctggggcctc 300

 attttggata tctgtgataa agttggtcag tctcgcactg gacctaagga 350

 ttgtcttcgg tctattatga gaagagtgaa ccacaaagat cctcacgttg 400

 ctatgcaggc tttgactctt ctaggagcat gtgtatcaaa ctgtggcaaa 450

 atttttcatt tagaagtatg ttcaagagat tttgctagtg aagtaagcaa 500

 cgtattaaat aagggtcatc ctaaagtatg tgaaaaatta aaggctctta 550

 tggttgaatg gacagatgaa tttaagaatg atccacagct tagtctaata 600

 tcagcaatga ttaagaacct taaggaacaa ggagttacgt tcccagctat 650

 tggctctcag gctgcagaac aagcaaaagc aagcccagct cttgtagcca 700

 aggatcctgg tactgtggct aacaaaaaag aagaagaaga tttagcaaaa 750

 gccattgagt tgtctctcaa ggaacaaagg cagcagtcaa ccaccctttc 800

 cactttgtat ccaagcacat ccagtctctt aactaaccac caacatgaag 850

 gccgaaaagt tcgtgctata tatgactttg aagctgctga agacaatgaa 900

 cttactttta aagctggaga aattattaca gttcttgatg acagtgatcc 950

 taactggtgg aaaggtgaaa cccatcaagg catagggtta tttccttcta 1000

 attttgtgac tgcagatctc actgctgaac cagaaatgat taaaacagag 1050

 aagaagacgg tacaatttag tgatgatgtt caggtagaga caatagaacc 1100

 agagccggaa ccagccttta ttgatgaaga taaaatggac cagttgctac 1150

 agatgctgca aagtacagac cccagtgatg atcagccaga cctaccagag 1200

 ctgcttcatc ttgaagcaat gtgtcaccag atgggacctc tcattgatga 1250

 aaagctggaa gatattgata gaaaacattc agaactctca gaacttaatg 1300

 tgaaagtgat ggaggccctt tccttatata ccaagttaat gaacgaagat 1350

 ccgatgtatt ccatgtatgc aaagttacag aatcagccat attatatgca 1400

 gtcatctggt gtttctggtt ctcaggtgta tgcagggcct cctccaagtg 1450

 gtgcctacct ggttgcaggg aacgcgcaga tgagccacct ccagagctac 1500

 agtcttcccc cggagcagct gtcttctctc agccaggcag tggtcccacc 1550

 atccgcaaac ccagcccttc ctagtcagca gactcaggcc gcttacccaa 1600

 atacaatggt cagttccgtt caaggaaaca catatcccag ccaggcgcca 1650

 gtatatagtc ctcctcctgc cgctactgct gctgctgcaa ctgccgatgt 1700

 cactctgtac cagaatgcag gacctaatat gccccaggtg ccaaactata 1750

 acttaacatc atcaactctg cctcagcccg gaggcagcca acagccacct 1800

 cagccacagc aaccatattc tcagaaggct ctgctatagg acccggtgtt 1850

 cctcttggtg gcagatacct gctaaatgcc actgacaatg ttatgagatt 1900

 cattactatc ttaagatgtg tttatcctca gcttatagga atctctccag 1950

 gtcaacaggt tcaaatattc aagaaggtag aactctcctc aatttacact 2000

 gactttttag aggttcttcc ccccccgccc ctgcagagga atgaaactac 2050

 ttacaacatt taattccttt cataatatga aagaattgat acaaggctat 2100

 ttgtctcgta aacctggtct gcagaaagtc aaacttacaa aaactgttgt 2150

 gacaaatgtt atgtacatat attgatatgt aactgcatta gtggccattt 2200

 tgaatcacag tggtgatcgt gtgaatatat ttaacactgt gttaaattaa 2250

 tttacgttgc tattttattt taatcataaa caactaccat gtttcttaat 2300

 gttttgtgta aatttaaggt aattatacta tccttttaaa cttcaagaaa 2350

 acaaagttgt tagcgtattt acatgaaggc gcattatgtt gtcgtgtgtt 2400

 tcagtttcac attaaactga accttttact aattgtgagc taaagagata 2450

 tatatatata tgtgtgtgta tatatatata tctacatgtc tttctgtagc 2500

 ctctgcatac tactggctgt catcacacca gcgtacagta gctaaatttt 2550

 tggtgcaatt atagcaaatg ataatgttcc cttttgaact tttacatttt 2600

 ggcatgacat ttcagagtat tgtgggacca tgagacaaaa ttaagtacga 2650

 tcacattctt tatttctcat tttaaagaaa tgatgttggt ttaccttttc 2700

 ctagttgaag atagtaatta ggtttctaag ctgtatactg tgtttattgg 2750

 tggcagtgac accaaagata gaggcaatgg atagaaattt ttaaactgga 2800

 aagaaaacct gaattacact acattttcga agtctcttgt aattatttgg 2850

 gatatcaaca aaatttgatt cgtctgtcta atcccttgct agtattttaa 2900

 atatgtcttt aacacattgt atcctttaat tcttcattaa aatggaaata 2950

 agtagatgtt tcaaagt 2967

<210> 914
<211> 540
<212> PRT
<213> Homo sapien

<400> 914
 Met Pro Leu Phe Ala Thr Asn Pro Phe Asp Gln Asp Val Glu Lys
   1               5                  10                  15

 Ala Thr Ser Glu Met Asn Thr Ala Glu Asp Trp Gly Leu Ile Leu
                  20                  25                  30

 Asp Ile Cys Asp Lys Val Gly Gln Ser Arg Thr Gly Pro Lys Asp
                  35                  40                  45

 Cys Leu Arg Ser Ile Met Arg Arg Val Asn His Lys Asp Pro His
                  50                  55                  60

 Val Ala Met Gln Ala Leu Thr Leu Leu Gly Ala Cys Val Ser Asn
                  65                  70                  75

 Cys Gly Lys Ile Phe His Leu Glu Val Cys Ser Arg Asp Phe Ala
                  80                  85                  90

 Ser Glu Val Ser Asn Val Leu Asn Lys Gly His Pro Lys Val Cys
                  95                 100                 105

 Glu Lys Leu Lys Ala Leu Met Val Glu Trp Thr Asp Glu Phe Lys
                 110                 115                 120

 Asn Asp Pro Gln Leu Ser Leu Ile Ser Ala Met Ile Lys Asn Leu
                 125                 130                 135

 Lys Glu Gln Gly Val Thr Phe Pro Ala Ile Gly Ser Gln Ala Ala
                 140                 145                 150

 Glu Gln Ala Lys Ala Ser Pro Ala Leu Val Ala Lys Asp Pro Gly
                 155                 160                 165

 Thr Val Ala Asn Lys Lys Glu Glu Glu Asp Leu Ala Lys Ala Ile
                 170                 175                 180

 Glu Leu Ser Leu Lys Glu Gln Arg Gln Gln Ser Thr Thr Leu Ser
                 185                 190                 195

 Thr Leu Tyr Pro Ser Thr Ser Ser Leu Leu Thr Asn His Gln His
                 200                 205                 210

 Glu Gly Arg Lys Val Arg Ala Ile Tyr Asp Phe Glu Ala Ala Glu
                 215                 220                 225

 Asp Asn Glu Leu Thr Phe Lys Ala Gly Glu Ile Ile Thr Val Leu
                 230                 235                 240

 Asp Asp Ser Asp Pro Asn Trp Trp Lys Gly Glu Thr His Gln Gly
                 245                 250                 255

 Ile Gly Leu Phe Pro Ser Asn Phe Val Thr Ala Asp Leu Thr Ala
                 260                 265                 270

 Glu Pro Glu Met Ile Lys Thr Glu Lys Lys Thr Val Gln Phe Ser
                 275                 280                 285

 Asp Asp Val Gln Val Glu Thr Ile Glu Pro Glu Pro Glu Pro Ala
                 290                 295                 300

 Phe Ile Asp Glu Asp Lys Met Asp Gln Leu Leu Gln Met Leu Gln
                 305                 310                 315

 Ser Thr Asp Pro Ser Asp Asp Gln Pro Asp Leu Pro Glu Leu Leu
                 320                 325                 330

 His Leu Glu Ala Met Cys His Gln Met Gly Pro Leu Ile Asp Glu
                 335                 340                 345

 Lys Leu Glu Asp Ile Asp Arg Lys His Ser Glu Leu Ser Glu Leu
                 350                 355                 360

 Asn Val Lys Val Met Glu Ala Leu Ser Leu Tyr Thr Lys Leu Met
                 365                 370                 375

 Asn Glu Asp Pro Met Tyr Ser Met Tyr Ala Lys Leu Gln Asn Gln
                 380                 385                 390

 Pro Tyr Tyr Met Gln Ser Ser Gly Val Ser Gly Ser Gln Val Tyr
                 395                 400                 405

 Ala Gly Pro Pro Pro Ser Gly Ala Tyr Leu Val Ala Gly Asn Ala
                 410                 415                 420

 Gln Met Ser His Leu Gln Ser Tyr Ser Leu Pro Pro Glu Gln Leu
                 425                 430                 435

 Ser Ser Leu Ser Gln Ala Val Val Pro Pro Ser Ala Asn Pro Ala
                 440                 445                 450

 Leu Pro Ser Gln Gln Thr Gln Ala Ala Tyr Pro Asn Thr Met Val
                 455                 460                 465

 Ser Ser Val Gln Gly Asn Thr Tyr Pro Ser Gln Ala Pro Val Tyr
                 470                 475                 480

 Ser Pro Pro Pro Ala Ala Thr Ala Ala Ala Ala Thr Ala Asp Val
                 485                 490                 495

 Thr Leu Tyr Gln Asn Ala Gly Pro Asn Met Pro Gln Val Pro Asn
                 500                 505                 510

 Tyr Asn Leu Thr Ser Ser Thr Leu Pro Gln Pro Gly Gly Ser Gln
                 515                 520                 525

 Gln Pro Pro Gln Pro Gln Gln Pro Tyr Ser Gln Lys Ala Leu Leu
                 530                 535                 540

<210> 915
<211> 728
<212> DNA
<213> Homo sapien

<400> 915
 gcggcctcag atgaatgcgg ctgttaagac ctgcaataat ccagaatggc 50

 tactctgatc tatgttgata aggaaaatgg agaaccaggc acccgtgtgg 100

 ttgctaagga tgggctgaag ctggggtctg gaccttcaat caaagcctta 150

 gatgggagat ctcaagtttc aacaccacgt tttggcaaaa cgttcgatgc 200

 cccaccagcc ttacctaaag ctactagaaa ggctttggga actgtcaaca 250

 gagctacaga aaagtctgta aagaccaagg gacccctcaa acaaaaacag 300

 ccaagctttt ctgccaaaaa gatgactgag aagactgtta aagcaaaaag 350

 ctctgttcct gcctcagatg atgcctatcc agaaatagaa aaattctttc 400

 ccttcaatcc tctagacttt gagagttttg acctgcctga agagcaccag 450

 attgcgcacc tccccttgag tggagtgcct ctcatgatcc ttgacgagga 500

 gagagagctt gaaaagctgt ttcagctggg ccccccttca cctgtgaaga 550

 tgccctctcc accatgggaa tccaatctgt tgcagtctcc ttcaagcatt 600

 ctgtcgaccc tggatgttga attgccacct gtttgctgtg acatagatat 650

 ttaaatttct tagtgcttca gagtttgtgt gtatttgtat taataaagca 700

 ttcttcaaca gaaaaaaaaa aaaaaaaa 728

<210> 916
<211> 202
<212> PRT
<213> Homo sapien

<400> 916
 Met Ala Thr Leu Ile Tyr Val Asp Lys Glu Asn Gly Glu Pro Gly
   1               5                  10                  15

 Thr Arg Val Val Ala Lys Asp Gly Leu Lys Leu Gly Ser Gly Pro
                  20                  25                  30

 Ser Ile Lys Ala Leu Asp Gly Arg Ser Gln Val Ser Thr Pro Arg
                  35                  40                  45

 Phe Gly Lys Thr Phe Asp Ala Pro Pro Ala Leu Pro Lys Ala Thr
                  50                  55                  60

 Arg Lys Ala Leu Gly Thr Val Asn Arg Ala Thr Glu Lys Ser Val
                  65                  70                  75

 Lys Thr Lys Gly Pro Leu Lys Gln Lys Gln Pro Ser Phe Ser Ala
                  80                  85                  90

 Lys Lys Met Thr Glu Lys Thr Val Lys Ala Lys Ser Ser Val Pro
                  95                 100                 105

 Ala Ser Asp Asp Ala Tyr Pro Glu Ile Glu Lys Phe Phe Pro Phe
                 110                 115                 120

 Asn Pro Leu Asp Phe Glu Ser Phe Asp Leu Pro Glu Glu His Gln
                 125                 130                 135

 Ile Ala His Leu Pro Leu Ser Gly Val Pro Leu Met Ile Leu Asp
                 140                 145                 150

 Glu Glu Arg Glu Leu Glu Lys Leu Phe Gln Leu Gly Pro Pro Ser
                 155                 160                 165

 Pro Val Lys Met Pro Ser Pro Pro Trp Glu Ser Asn Leu Leu Gln
                 170                 175                 180

 Ser Pro Ser Ser Ile Leu Ser Thr Leu Asp Val Glu Leu Pro Pro
                 185                 190                 195

 Val Cys Cys Asp Ile Asp Ile
                 200

<210> 917
<211> 4089
<212> DNA
<213> Homo sapien

<400> 917
 cgcgttcaca gccccagcgc aggtctggat gtaccgactg cttttggaat 50

 aaaaagattc ccaggatgtg agcaacacgg gaccgatatg atgcttcctg 100

 gtgtgtttag tggttggtgc cattccaatt ttctgtgctg aaatcattct 150

 gaaaactcaa acagtagact tcagcacaca aggaaagcca aagccatttg 200

 agggggaata aagccaaaag cctttcacct tattcgttcc aagaatctca 250

 ccgccccctc cttatccccc tccaaaaata agccattgca cacagacagg 300

 cagcatggct agcaaacgaa aatctacaac tccatgcatg gttcggacat 350

 cacaagtagt agaacaagat gtgcccgagg aagtagacag ggccaaagag 400

 aaaggaatcg gcacaccaca gcctgacgtg gccaaggaca gttgggcagc 450

 agaacttgaa aactcttcca aagaaaacga agtgatagag gtgaaatcta 500

 tgggggaaag ccagtccaaa aaactccaag gtggttatga gtgcaaatac 550

 tgcccctact ccacgcaaaa cctgaacgag ttcacggagc atgtcgacat 600

 gcagcatccc aacgtgattc tcaaccccct ctacgtgtgt gcagaatgta 650

 acttcacaac caaaaagtac gactccctat ccgaccacaa ctccaagttc 700

 catcccgggg aggccaactt caagctgaag ttaattaaac gcaataatca 750

 aactgtcttg gaacagtcca tcgaaaccac caaccatgtc gtgtccatca 800

 ccaccagtgg ccctggaact ggtgacagtg attctgggat ctcggtgagt 850

 aaaaccccca tcatgaagcc tggaaaacca aaagcggatg ccaagaaggt 900

 gcccaagaag cccgaggaga tcacccccga gaaccacgtg gaagggaccg 950

 cccgcctggt gacagacaca gctgagatcc tctcaagact cggcggggtg 1000

 gagctcctcc aagacacatt aggacacgtc atgccttctg tacagctgcc 1050

 accaaatatc aaccttgtgc ccaaggtccc tgtcccacta aatactacca 1100

 aatacaactc tgccctggat acaaatgcca cgatgatcaa ctctttcaac 1150

 aagtttcctt acccgaccca ggctgagttg tcctggctga cagctgcctc 1200

 caaacaccca gaggagcaca tcagaatctg gtttgccacc cagcgcttaa 1250

 agcatggcat cagctggtcc ccagaagagg tggaggaggc ccggaagaag 1300

 atgttcaacg gcaccatcca gtcagtaccc ccgaccatca ctgtgctgcc 1350

 cgcccagttg gcccccacaa aggtgacgca gcccatcctc cagacggctc 1400

 taccgtgcca gatcctcggc cagactagcc tggtgctgac tcaggtgacc 1450

 agcgggtcaa caaccgtctc ttgctccccc atcacacttg ccgtggcagg 1500

 agtcactaac catggccaga agagaccctt ggtgactccc caagctgccc 1550

 ccgaacccaa gcgtccacac atcgctcagg tgccagagcc cccacccaag 1600

 gtggccaacc ccccgctcac accagccagt gaccgcaaga agacaaagga 1650

 gcagatagca catctcaagg ccagctttct ccagagccag ttccctgacg 1700

 atgccgaggt ttaccggctc atcgaggtga ctggccttgc caggagcgag 1750

 atcaagaagt ggttcagtga ccaccgatat cggtgtcaaa ggggcatcgt 1800

 ccacatcacc agcgaatccc ttgccaaaga ccagttggcc atcgcggcct 1850

 cccgacacgg tcgcacgtat catgcgtacc cagactttgc cccccagaag 1900

 ttcaaagaga aaacacaggg tcaggttaaa atcttggaag acagcttttt 1950

 gaaaagttct tttcctaccc aagcagaact ggatcggcta agggtggaga 2000

 ccaagctgag caggagagag atcgactcct ggttctcgga gaggcggaag 2050

 cttcgagaca gcatggaaca agctgtcttg gattccatgg ggtctggcaa 2100

 aaaaggccaa gatgtgggag cccccaatgg tgctctgtct cgactcgacc 2150

 agctctccgg tgcccagtta acaagttctc tgcccagccc ttcgccagca 2200

 attgcaaaaa gtcaagaaca ggttcatctc ctgaggagca cgtttgcaag 2250

 aacccagtgg cctactcccc aggagtacga ccagttagcg gccaagactg 2300

 gcctggtccg aactgagatt gtgcgttggt tcaaggagaa cagatgcttg 2350

 ctgaaaacgg gaaccgtgaa gtggatggag cagtaccagc accagcccat 2400

 ggcagatgat cacggctacg atgccgtagc aaggaaagca acaaaaccca 2450

 tggccgagag cccaaagaac gggggtgatg tggttccaca atattacaag 2500

 gaccccaaaa agctctgcga agaggacttg gagaagttgg tgaccagggt 2550

 aaaagtaggc agcgagccag caaaagactg tttgccagca aagccctcag 2600

 aggccacctc agaccggtca gagggcagca gccgggacgg ccagggtagc 2650

 gacgagaacg aggagtcgag cgttgtggat tacgtggagg tgacggtcgg 2700

 ggaggaggat gcgatctcag atagatcaga tagctggagt caggctgcgg 2750

 cagaaggtgt gtcggaactg gctgaatcag actccgactg cgtccctgca 2800

 gaggctggcc aggcctagac agggaagtct gttagaactg ctgtgctgat 2850

 caacgggacg ctccgtcttt gaagaaagaa gagatggtct ctccccagcc 2900

 atgggccacc cttgccagtg actccaagtg gaactactta gctcgcgtgt 2950

 gcctggaggg tgcgggaagt ccagcgactc tcagacgcac ctcccagagg 3000

 accggtggga attgttcata gtgccaaagt cctactactg cgttttcagt 3050

 gggtccttgt acatagtttg ctcctctgcc ctagccctca cctcttgcta 3100

 tactggaacc gatttgtaca atgtgggaat tttgttacct ttttaatcaa 3150

 gggcaacttc cttttccagc actaccattg taaggttttt ttcaggaggg 3200

 agggctaacc accttgcttt tctcttttct ctttttcttt tttttatttt 3250

 tgttttatta atttggggaa aggggtgtta gcattagtgc catgatatct 3300

 actggatttt aagtagggag actttatttt taaaggtagg ttgaaatttg 3350

 ggagatttct cggcaggaag ggctgaaatc caggcccctg tctcaacttg 3400

 gagagaggtg acagacggca gatcttccaa atcaaattcc tttccagttc 3450

 ttcccctggc tgcctttttg ggggtccctg ccttagcccc acacaaggct 3500

 ttctgaactg ccaagagggg atctggcttc tcaactgctc ggcctcttgg 3550

 gccaggctgt gcccagccag ccctgggaga actgggtagc aggtggctga 3600

 cttctttaag cacctttcta aataccagca gaagaggctc ccgcctctgt 3650

 tagcatgatc agtactattg tgacattaaa acaacaacaa taagatcttc 3700

 ctatctggag ggtacagagg tgaatggctt tggttttcat ttctcttctt 3750

 cactgccttt tctcggtgtg gtatttgaca agattttagc tcaaagcctc 3800

 accatgaatt gatttttttt gtttgtgtgt gtgtttgttt tgggacaatt 3850

 ttagatacct gagtgcactt tttcagttag tcctaacttt taaaagaagg 3900

 aaaaccaaga gacatatctg gtgtacgtgt tgcagtatga actctggttg 3950

 caatccctcc ccctcccaca ctgcccccca tttgagtacg ccgcacaagt 4000

 caaacgctag gaagtttgaa taaaaccaat ttttctaact tgttgctcat 4050

 ttgttgtaac tcaataaagc aaagactaaa catttttat 4089

<210> 918
<211> 837
<212> PRT
<213> Homo sapien

<400> 918
 Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Val Arg Thr
   1               5                  10                  15

 Ser Gln Val Val Glu Gln Asp Val Pro Glu Glu Val Asp Arg Ala
                  20                  25                  30

 Lys Glu Lys Gly Ile Gly Thr Pro Gln Pro Asp Val Ala Lys Asp
                  35                  40                  45

 Ser Trp Ala Ala Glu Leu Glu Asn Ser Ser Lys Glu Asn Glu Val
                  50                  55                  60

 Ile Glu Val Lys Ser Met Gly Glu Ser Gln Ser Lys Lys Leu Gln
                  65                  70                  75

 Gly Gly Tyr Glu Cys Lys Tyr Cys Pro Tyr Ser Thr Gln Asn Leu
                  80                  85                  90

 Asn Glu Phe Thr Glu His Val Asp Met Gln His Pro Asn Val Ile
                  95                 100                 105

 Leu Asn Pro Leu Tyr Val Cys Ala Glu Cys Asn Phe Thr Thr Lys
                 110                 115                 120

 Lys Tyr Asp Ser Leu Ser Asp His Asn Ser Lys Phe His Pro Gly
                 125                 130                 135

 Glu Ala Asn Phe Lys Leu Lys Leu Ile Lys Arg Asn Asn Gln Thr
                 140                 145                 150

 Val Leu Glu Gln Ser Ile Glu Thr Thr Asn His Val Val Ser Ile
                 155                 160                 165

 Thr Thr Ser Gly Pro Gly Thr Gly Asp Ser Asp Ser Gly Ile Ser
                 170                 175                 180

 Val Ser Lys Thr Pro Ile Met Lys Pro Gly Lys Pro Lys Ala Asp
                 185                 190                 195

 Ala Lys Lys Val Pro Lys Lys Pro Glu Glu Ile Thr Pro Glu Asn
                 200                 205                 210

 His Val Glu Gly Thr Ala Arg Leu Val Thr Asp Thr Ala Glu Ile
                 215                 220                 225

 Leu Ser Arg Leu Gly Gly Val Glu Leu Leu Gln Asp Thr Leu Gly
                 230                 235                 240

 His Val Met Pro Ser Val Gln Leu Pro Pro Asn Ile Asn Leu Val
                 245                 250                 255

 Pro Lys Val Pro Val Pro Leu Asn Thr Thr Lys Tyr Asn Ser Ala
                 260                 265                 270

 Leu Asp Thr Asn Ala Thr Met Ile Asn Ser Phe Asn Lys Phe Pro
                 275                 280                 285

 Tyr Pro Thr Gln Ala Glu Leu Ser Trp Leu Thr Ala Ala Ser Lys
                 290                 295                 300

 His Pro Glu Glu His Ile Arg Ile Trp Phe Ala Thr Gln Arg Leu
                 305                 310                 315

 Lys His Gly Ile Ser Trp Ser Pro Glu Glu Val Glu Glu Ala Arg
                 320                 325                 330

 Lys Lys Met Phe Asn Gly Thr Ile Gln Ser Val Pro Pro Thr Ile
                 335                 340                 345

 Thr Val Leu Pro Ala Gln Leu Ala Pro Thr Lys Val Thr Gln Pro
                 350                 355                 360

 Ile Leu Gln Thr Ala Leu Pro Cys Gln Ile Leu Gly Gln Thr Ser
                 365                 370                 375

 Leu Val Leu Thr Gln Val Thr Ser Gly Ser Thr Thr Val Ser Cys
                 380                 385                 390

 Ser Pro Ile Thr Leu Ala Val Ala Gly Val Thr Asn His Gly Gln
                 395                 400                 405

 Lys Arg Pro Leu Val Thr Pro Gln Ala Ala Pro Glu Pro Lys Arg
                 410                 415                 420

 Pro His Ile Ala Gln Val Pro Glu Pro Pro Pro Lys Val Ala Asn
                 425                 430                 435

 Pro Pro Leu Thr Pro Ala Ser Asp Arg Lys Lys Thr Lys Glu Gln
                 440                 445                 450

 Ile Ala His Leu Lys Ala Ser Phe Leu Gln Ser Gln Phe Pro Asp
                 455                 460                 465

 Asp Ala Glu Val Tyr Arg Leu Ile Glu Val Thr Gly Leu Ala Arg
                 470                 475                 480

 Ser Glu Ile Lys Lys Trp Phe Ser Asp His Arg Tyr Arg Cys Gln
                 485                 490                 495

 Arg Gly Ile Val His Ile Thr Ser Glu Ser Leu Ala Lys Asp Gln
                 500                 505                 510

 Leu Ala Ile Ala Ala Ser Arg His Gly Arg Thr Tyr His Ala Tyr
                 515                 520                 525

 Pro Asp Phe Ala Pro Gln Lys Phe Lys Glu Lys Thr Gln Gly Gln
                 530                 535                 540

 Val Lys Ile Leu Glu Asp Ser Phe Leu Lys Ser Ser Phe Pro Thr
                 545                 550                 555

 Gln Ala Glu Leu Asp Arg Leu Arg Val Glu Thr Lys Leu Ser Arg
                 560                 565                 570

 Arg Glu Ile Asp Ser Trp Phe Ser Glu Arg Arg Lys Leu Arg Asp
                 575                 580                 585

 Ser Met Glu Gln Ala Val Leu Asp Ser Met Gly Ser Gly Lys Lys
                 590                 595                 600

 Gly Gln Asp Val Gly Ala Pro Asn Gly Ala Leu Ser Arg Leu Asp
                 605                 610                 615

 Gln Leu Ser Gly Ala Gln Leu Thr Ser Ser Leu Pro Ser Pro Ser
                 620                 625                 630

 Pro Ala Ile Ala Lys Ser Gln Glu Gln Val His Leu Leu Arg Ser
                 635                 640                 645

 Thr Phe Ala Arg Thr Gln Trp Pro Thr Pro Gln Glu Tyr Asp Gln
                 650                 655                 660

 Leu Ala Ala Lys Thr Gly Leu Val Arg Thr Glu Ile Val Arg Trp
                 665                 670                 675

 Phe Lys Glu Asn Arg Cys Leu Leu Lys Thr Gly Thr Val Lys Trp
                 680                 685                 690

 Met Glu Gln Tyr Gln His Gln Pro Met Ala Asp Asp His Gly Tyr
                 695                 700                 705

 Asp Ala Val Ala Arg Lys Ala Thr Lys Pro Met Ala Glu Ser Pro
                 710                 715                 720

 Lys Asn Gly Gly Asp Val Val Pro Gln Tyr Tyr Lys Asp Pro Lys
                 725                 730                 735

 Lys Leu Cys Glu Glu Asp Leu Glu Lys Leu Val Thr Arg Val Lys
                 740                 745                 750

 Val Gly Ser Glu Pro Ala Lys Asp Cys Leu Pro Ala Lys Pro Ser
                 755                 760                 765

 Glu Ala Thr Ser Asp Arg Ser Glu Gly Ser Ser Arg Asp Gly Gln
                 770                 775                 780

 Gly Ser Asp Glu Asn Glu Glu Ser Ser Val Val Asp Tyr Val Glu
                 785                 790                 795

 Val Thr Val Gly Glu Glu Asp Ala Ile Ser Asp Arg Ser Asp Ser
                 800                 805                 810

 Trp Ser Gln Ala Ala Ala Glu Gly Val Ser Glu Leu Ala Glu Ser
                 815                 820                 825

 Asp Ser Asp Cys Val Pro Ala Glu Ala Gly Gln Ala
                 830                 835

<210> 919
<211> 1280
<212> DNA
<213> Homo sapien

<400> 919
 tgccgcagcc cccgcccgcc cgcagagctt ttgaaaggcg gcgggaggcg 50

 gcgagcgcca tggccagtcc gggctgcctg ctgtgcgtgc tgggcctgct 100

 actctgcggg gcggcgagcc tcgagctgtc tagaccccac ggcgacaccg 150

 ccaagaagcc catcatcgga atattaatgc aaaaatgccg taataaagtc 200

 atgaaaaact atggaagata ctatattgct gcgtcctatg taaagtactt 250

 ggagtctgca ggtgcgagag ttgtaccagt aaggctggat cttacagaga 300

 aagactatga aatacttttc aaatctatta atggaatcct tttccctgga 350

 ggaagtgttg acctcagacg ctcagattat gctaaagtgg ccaaaatatt 400

 ttataacttg tccatacaga gttttgatga tggagactat tttcctgtgt 450

 ggggcacatg ccttggattt gaagagcttt cactgctgat tagtggagag 500

 tgcttattaa ctgccacaga tactgttgac gtggcaatgc cgctgaactt 550

 cactggaggt caattgcaca gcagaatgtt ccagaatttt cctactgagt 600

 tgttgctgtc attagcagta gaacctctga ctgccaattt ccataagtgg 650

 agcctctccg tgaagaattt tacaatgaat gaaaagttaa agaagttttt 700

 caatgtctta actacaaata cagatggcaa gattgagttt atttcaacaa 750

 tggaaggata taagtatcca gtatatggtg tccagtggca tccagagaaa 800

 gcaccttatg agtggaagaa tttggatggc atttcccatg cacctaatgc 850

 tgtgaaaacc gcattttatt tagcagagtt ttttgttaat gaagctcgga 900

 aaaacaacca tcattttaaa tctgaatctg aagaggagaa agcattgatt 950

 tatcagttca gtccaattta tactggaaat atttcttcat ttcagcaatg 1000

 ttacatattt gattgaaagt cttcaatttg ttaacagagc aaatttgaat 1050

 aattccatga ttaaactgtt agaataactt gctactcatg gcaagattag 1100

 gaagtcacag attcttttct ataatgtgcc tggctctgat tcttcattat 1150

 gtatgtgact atttatataa cattagataa ttaaatagtg agacataaat 1200

 agagtgcttt ttcatggaaa agccttctta tatctgaaga ttgaaaaata 1250

 aatttactga aatacaaaaa aaaaaaaaaa 1280

<210> 920
<211> 318
<212> PRT
<213> Homo sapien

<400> 920
 Met Ala Ser Pro Gly Cys Leu Leu Cys Val Leu Gly Leu Leu Leu
   1               5                  10                  15

 Cys Gly Ala Ala Ser Leu Glu Leu Ser Arg Pro His Gly Asp Thr
                  20                  25                  30

 Ala Lys Lys Pro Ile Ile Gly Ile Leu Met Gln Lys Cys Arg Asn
                  35                  40                  45

 Lys Val Met Lys Asn Tyr Gly Arg Tyr Tyr Ile Ala Ala Ser Tyr
                  50                  55                  60

 Val Lys Tyr Leu Glu Ser Ala Gly Ala Arg Val Val Pro Val Arg
                  65                  70                  75

 Leu Asp Leu Thr Glu Lys Asp Tyr Glu Ile Leu Phe Lys Ser Ile
                  80                  85                  90

 Asn Gly Ile Leu Phe Pro Gly Gly Ser Val Asp Leu Arg Arg Ser
                  95                 100                 105

 Asp Tyr Ala Lys Val Ala Lys Ile Phe Tyr Asn Leu Ser Ile Gln
                 110                 115                 120

 Ser Phe Asp Asp Gly Asp Tyr Phe Pro Val Trp Gly Thr Cys Leu
                 125                 130                 135

 Gly Phe Glu Glu Leu Ser Leu Leu Ile Ser Gly Glu Cys Leu Leu
                 140                 145                 150

 Thr Ala Thr Asp Thr Val Asp Val Ala Met Pro Leu Asn Phe Thr
                 155                 160                 165

 Gly Gly Gln Leu His Ser Arg Met Phe Gln Asn Phe Pro Thr Glu
                 170                 175                 180

 Leu Leu Leu Ser Leu Ala Val Glu Pro Leu Thr Ala Asn Phe His
                 185                 190                 195

 Lys Trp Ser Leu Ser Val Lys Asn Phe Thr Met Asn Glu Lys Leu
                 200                 205                 210

 Lys Lys Phe Phe Asn Val Leu Thr Thr Asn Thr Asp Gly Lys Ile
                 215                 220                 225

 Glu Phe Ile Ser Thr Met Glu Gly Tyr Lys Tyr Pro Val Tyr Gly
                 230                 235                 240

 Val Gln Trp His Pro Glu Lys Ala Pro Tyr Glu Trp Lys Asn Leu
                 245                 250                 255

 Asp Gly Ile Ser His Ala Pro Asn Ala Val Lys Thr Ala Phe Tyr
                 260                 265                 270

 Leu Ala Glu Phe Phe Val Asn Glu Ala Arg Lys Asn Asn His His
                 275                 280                 285

 Phe Lys Ser Glu Ser Glu Glu Glu Lys Ala Leu Ile Tyr Gln Phe
                 290                 295                 300

 Ser Pro Ile Tyr Thr Gly Asn Ile Ser Ser Phe Gln Gln Cys Tyr
                 305                 310                 315

 Ile Phe Asp


<210> 921
<211> 1702
<212> DNA
<213> Homo sapien

<400> 921
 ctggctctcc gctgcgctgc gctgcgctcc ggccgctccc gcggcccgtg 50

 gatgggggtg tccggctgag ccccgggatc cgcctccctc cgccaggacc 100

 cgcacagata aactcatcct gaaagtcgct gttgttctcc tgctgagcaa 150

 gaatggaggc cccactggtg agtctggatg aagagtttga ggaccttcga 200

 ccctcctgct cggaggaccc ggaggagaag ccccagtgtt tctatggttc 250

 atctccccac catctcgagg acccctccct ctccgagctt gagaattttt 300

 cttccgaaat aatcagcttc aagtccatgg aggacctcgt aaatgaattt 350

 gatgagaagc tcaatgtctg ctttcggaac tacaacgcca agaccgagaa 400

 cctagctccc gtgaagaacc agttacagat ccaagaggag gaggagaccc 450

 ttcaggacga ggaggtttgg gatgctctga cagacaatta catcccttca 500

 ctctcagaag actggaggga tccaaacatc gaggctctga atggcaactg 550

 ctctgacact gagatccatg agaaagaaga ggaagagttc aatgagaaga 600

 gtgaaaatga ttccggtatc aacgaggagc ctctgctcac agcagatcag 650

 gtaattgagg agattgagga aatgatgcag aactccccag accctgagga 700

 agaagaggag gttctggaag aagaggatgg aggagaaact tcctcccagg 750

 cagactcggt cctcctgcag gagatgcagg cattgacaca gaccttcaac 800

 aacaactggt cctatgaagg gctgaggcac atgtctgggt ctgagctgac 850

 cgagctgctg gaccaggtgg agggtgccat ccgtgacttc tcggaggagc 900

 tggtgcagca gctggcccgc cgggacgagc tggagtttga gaaggaagtg 950

 aagaactcct ttatcacggt gcttattgag gttcagaaca agcagaagga 1000

 gcagcgagaa ctgatgaaaa agaggcggaa agagaaaggg ctgagcctgc 1050

 agagcagccg gatagagaag ggaaaccaga tgcctctcaa gcgcttcagc 1100

 atggaaggca tctccaacat tctgcagagt ggcatccgcc agacctttgg 1150

 ctcctcagga actgacaaac agtatctgaa cacagtcatt ccttacgaga 1200

 agaaagcctc tcctccctca gtggaagacc tgcagatgct gacaaacatt 1250

 ctctttgcca tgaaggagga taatgagaag gtgcctactt tgctaacgga 1300

 ctacatttta aaagtgctct gccctaccta accttgccct ttggagcagc 1350

 ctcgctgcag gaggtcactg agcaagagtc attccatcac agggactgca 1400

 tgagaccatg taacctccga catgtattta aacgtgtata gcttaacctg 1450

 gattaaacac gagcaagcgc gcggggtcct ttgccgttgg cttctagtgc 1500

 tagtaatcat tggatgcatg atggggcagg gccggtgatg gtgcctcccc 1550

 cttgctggtg tcaggagagg ggaaggcagc cgctttcacc gctcattatg 1600

 tagtctggct acagccctca aaaacagctt atactcttaa gactaatttt 1650

 gaaataaaac cttcatttaa ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aa 1702

<210> 922
<211> 392
<212> PRT
<213> Homo sapien

<400> 922
 Met Glu Ala Pro Leu Val Ser Leu Asp Glu Glu Phe Glu Asp Leu
   1               5                  10                  15

 Arg Pro Ser Cys Ser Glu Asp Pro Glu Glu Lys Pro Gln Cys Phe
                  20                  25                  30

 Tyr Gly Ser Ser Pro His His Leu Glu Asp Pro Ser Leu Ser Glu
                  35                  40                  45

 Leu Glu Asn Phe Ser Ser Glu Ile Ile Ser Phe Lys Ser Met Glu
                  50                  55                  60

 Asp Leu Val Asn Glu Phe Asp Glu Lys Leu Asn Val Cys Phe Arg
                  65                  70                  75

 Asn Tyr Asn Ala Lys Thr Glu Asn Leu Ala Pro Val Lys Asn Gln
                  80                  85                  90

 Leu Gln Ile Gln Glu Glu Glu Glu Thr Leu Gln Asp Glu Glu Val
                  95                 100                 105

 Trp Asp Ala Leu Thr Asp Asn Tyr Ile Pro Ser Leu Ser Glu Asp
                 110                 115                 120

 Trp Arg Asp Pro Asn Ile Glu Ala Leu Asn Gly Asn Cys Ser Asp
                 125                 130                 135

 Thr Glu Ile His Glu Lys Glu Glu Glu Glu Phe Asn Glu Lys Ser
                 140                 145                 150

 Glu Asn Asp Ser Gly Ile Asn Glu Glu Pro Leu Leu Thr Ala Asp
                 155                 160                 165

 Gln Val Ile Glu Glu Ile Glu Glu Met Met Gln Asn Ser Pro Asp
                 170                 175                 180

 Pro Glu Glu Glu Glu Glu Val Leu Glu Glu Glu Asp Gly Gly Glu
                 185                 190                 195

 Thr Ser Ser Gln Ala Asp Ser Val Leu Leu Gln Glu Met Gln Ala
                 200                 205                 210

 Leu Thr Gln Thr Phe Asn Asn Asn Trp Ser Tyr Glu Gly Leu Arg
                 215                 220                 225

 His Met Ser Gly Ser Glu Leu Thr Glu Leu Leu Asp Gln Val Glu
                 230                 235                 240

 Gly Ala Ile Arg Asp Phe Ser Glu Glu Leu Val Gln Gln Leu Ala
                 245                 250                 255

 Arg Arg Asp Glu Leu Glu Phe Glu Lys Glu Val Lys Asn Ser Phe
                 260                 265                 270

 Ile Thr Val Leu Ile Glu Val Gln Asn Lys Gln Lys Glu Gln Arg
                 275                 280                 285

 Glu Leu Met Lys Lys Arg Arg Lys Glu Lys Gly Leu Ser Leu Gln
                 290                 295                 300

 Ser Ser Arg Ile Glu Lys Gly Asn Gln Met Pro Leu Lys Arg Phe
                 305                 310                 315

 Ser Met Glu Gly Ile Ser Asn Ile Leu Gln Ser Gly Ile Arg Gln
                 320                 325                 330

 Thr Phe Gly Ser Ser Gly Thr Asp Lys Gln Tyr Leu Asn Thr Val
                 335                 340                 345

 Ile Pro Tyr Glu Lys Lys Ala Ser Pro Pro Ser Val Glu Asp Leu
                 350                 355                 360

 Gln Met Leu Thr Asn Ile Leu Phe Ala Met Lys Glu Asp Asn Glu
                 365                 370                 375

 Lys Val Pro Thr Leu Leu Thr Asp Tyr Ile Leu Lys Val Leu Cys
                 380                 385                 390

 Pro Thr


<210> 923
<211> 3286
<212> DNA
<213> Homo sapien

<400> 923
 tagcagcgaa tatactttac accaaatctc agaagattca gaacttagat 50

 gagtggggcc caggacagga accctggagc cttggaagga ggggagcccc 100

 atctccccag aagagcagtg accccagcag agaggggcct ggtgtatcac 150

 tggaggaaat agcctgccaa ggaatacacg tcttcagaag aaattctgtg 200

 tggcttcaag agactgatca aattgtgaga ggaaaacagc ctacccggtc 250

 ctcttttctt caatacaaaa tgagataata ggggttggaa ggaaaacctt 300

 caagacctat ggaagtcagt tgcagccagc tcatcacata gaggtgcagg 350

 tgaggtgtat tttcatcacg gtggaaaatt ctggctgctt catctccatc 400

 tctagagcca atattggagc ttttcaataa aagctatggc ctcaaccacc 450

 agcaccaaga agatgatgga ggaagccacc tgctccatct gcctgagcct 500

 gatgacgaac ccagtaagca tcaactgtgg acacagctac tgccacttgt 550

 gtataacaga cttctttaaa aacccaagcc aaaagcaact gaggcaggag 600

 acattctgct gtccccagtg tcgggctcca tttcatatgg atagcctccg 650

 acccaacaag cagctgggaa gcctcattga agccctcaaa gagacggatc 700

 aagaaatgtc atgtgaggaa cacggagagc agttccacct gttctgcgaa 750

 gacgaggggc agctcatctg ctggcgctgt gagcgggcac cacagcacaa 800

 agggcacacc acagctcttg ttgaagacgt atgccagggc tacaaggaaa 850

 agctccagaa agctgtgaca aaactgaagc aacttgaaga cagatgtacg 900

 gagcagaagc tgtccacagc aatgcgaata actaaatgga aagagaaggt 950

 acagattcag agacaaaaaa tccggtctga ctttaagaat ctccagtgtt 1000

 tcctacatga ggaagagaag tcttatctct ggaggctgga gaaagaagaa 1050

 caacagactc tgagtagact gagggactat gaggctggtc tggggctgaa 1100

 gagcaatgaa ctcaagagcc acatcctgga actggaggaa aaatgtcagg 1150

 gctcagccca gaaattgctg cagaatgtga atgacacttt gagcaggagt 1200

 tgggctgtga agctggaaac atcagaggct gtctccttgg aacttcatac 1250

 tatgtgcaat gtttccaagc tttacttcga tgtgaagaaa atgttaagga 1300

 gtcatcaagt tagtgtgact ctggatccag atacagctca tcacgaacta 1350

 attctctctg aggatcggag acaagtgact cgtggataca cccaggagaa 1400

 tcaggacaca tcttccagga gatttactgc cttcccctgt gtcttgggtt 1450

 gtgaaggctt cacctcagga agacgttact ttgaagtgga tgttggcgaa 1500

 ggaaccggat gggatttagg agtttgtatg gaaaatgtgc agaggggcac 1550

 tggcatgaag caagagcctc agtctggatt ctggaccctc aggctgtgca 1600

 aaaagaaagg ctatgtagca cttacttctc ccccaacttc ccttcatctg 1650

 catgagcagc ccctgcttgt gggaattttt ctggactatg aggccggagt 1700

 tgtatccttt tataacggga atactggctg ccacatcttt actttcccga 1750

 aggcttcctt ctctgatact ctccggccct atttccaggt ttatcaatat 1800

 tctcctttgt ttctgcctcc cccaggtgac taaggaaaag agcagaagct 1850

 ccttggttta accagcacag agaaaataat ataaatccca taagggcaga 1900

 cgtttggtct gttttcttcg ctgtcatttc cttagtagtt agactagtgc 1950

 tgagatttta gtggatatat aattgattta tgttgaatat atggacttag 2000

 caactaaaaa taccacagat ggttaacctg gactggggca aagcaagata 2050

 atagtgatga tcgtatgttg ctgtctccat ccgtctttaa tgggtcaggg 2100

 ctttgatttc caagggtctt caggtgatga gtaggggtac ccacaagtca 2150

 gaaggtctgc gttctcctag tttgtttgct gccatttgaa ctcatgtagg 2200

 gaatgaaaga aagctgcaat tatccgccaa ctgcatttaa aacaaaacaa 2250

 aacagaaaaa tcaaaataac attgactctt ccaaccactg acatgttgtt 2300

 taataatcta agcggcagtc ctggaggcta ccagacttac tgagttctac 2350

 ctgagaaaca gccaagcaaa gtgtgagaga agggttaaga ctggcttaca 2400

 atgagatgct tcaaatgaaa agggaattat gagtaaaatt gaactttgat 2450

 gggggattca gttctggaaa agaatttggt attttccagt ctgctaggac 2500

 caattacctt gaaatatttt aaaatctcag taaatagtta ttgctgaaat 2550

 ggctgttggc agttcttatt atgattcaga gaagagcaaa tagaccttaa 2600

 cttcattttg aaaaagacca aattaccata cccgagtgag taatgacagg 2650

 actacaacta aaacataaac aacattaatg atgaccataa aaagtcacaa 2700

 aattgctaaa tgttataatt tagagttgac ataaaaattg atggccaggc 2750

 atggtggctc acgcctgtaa tcccagaact atgtgaggct gaggcaggtg 2800

 gatcacttga ggtcaggagt tcaacaccag cctggccaac atggtgaaac 2850

 cctgtctcta ctaaaaatac aaaaattagc cgggcatggt ggtaggggcc 2900

 tgtaacccag ctactcgtga ggccaaggca ggagaattgc ttgagcctgc 2950

 agcagctgca gtaagccaag atcatgctgt gcctcaagga aaaaaaaaat 3000

 taatgtttac tgatatttgt tgaagtccta caacatcacc tctgagaata 3050

 ggagaaatga agcaacagtt gtgtctagat gtcagaggca tggctgggcc 3100

 tccatctctg cctaagggag atataaaaga gttcaaacta ttgcccatgt 3150

 tccccagggt cagaagttct aattatgatg atagaggctg ggttgtaagt 3200

 agtaagtgaa gggtagcaga atatgccatc tttggcataa gaagtatttt 3250

 gagttgaaga caattgagaa aaaaaaaaaa aaaaaa 3286

<210> 924
<211> 465
<212> PRT
<213> Homo sapien

<400> 924
 Met Ala Ser Thr Thr Ser Thr Lys Lys Met Met Glu Glu Ala Thr
   1               5                  10                  15

 Cys Ser Ile Cys Leu Ser Leu Met Thr Asn Pro Val Ser Ile Asn
                  20                  25                  30

 Cys Gly His Ser Tyr Cys His Leu Cys Ile Thr Asp Phe Phe Lys
                  35                  40                  45

 Asn Pro Ser Gln Lys Gln Leu Arg Gln Glu Thr Phe Cys Cys Pro
                  50                  55                  60

 Gln Cys Arg Ala Pro Phe His Met Asp Ser Leu Arg Pro Asn Lys
                  65                  70                  75

 Gln Leu Gly Ser Leu Ile Glu Ala Leu Lys Glu Thr Asp Gln Glu
                  80                  85                  90

 Met Ser Cys Glu Glu His Gly Glu Gln Phe His Leu Phe Cys Glu
                  95                 100                 105

 Asp Glu Gly Gln Leu Ile Cys Trp Arg Cys Glu Arg Ala Pro Gln
                 110                 115                 120

 His Lys Gly His Thr Thr Ala Leu Val Glu Asp Val Cys Gln Gly
                 125                 130                 135

 Tyr Lys Glu Lys Leu Gln Lys Ala Val Thr Lys Leu Lys Gln Leu
                 140                 145                 150

 Glu Asp Arg Cys Thr Glu Gln Lys Leu Ser Thr Ala Met Arg Ile
                 155                 160                 165

 Thr Lys Trp Lys Glu Lys Val Gln Ile Gln Arg Gln Lys Ile Arg
                 170                 175                 180

 Ser Asp Phe Lys Asn Leu Gln Cys Phe Leu His Glu Glu Glu Lys
                 185                 190                 195

 Ser Tyr Leu Trp Arg Leu Glu Lys Glu Glu Gln Gln Thr Leu Ser
                 200                 205                 210

 Arg Leu Arg Asp Tyr Glu Ala Gly Leu Gly Leu Lys Ser Asn Glu
                 215                 220                 225

 Leu Lys Ser His Ile Leu Glu Leu Glu Glu Lys Cys Gln Gly Ser
                 230                 235                 240

 Ala Gln Lys Leu Leu Gln Asn Val Asn Asp Thr Leu Ser Arg Ser
                 245                 250                 255

 Trp Ala Val Lys Leu Glu Thr Ser Glu Ala Val Ser Leu Glu Leu
                 260                 265                 270

 His Thr Met Cys Asn Val Ser Lys Leu Tyr Phe Asp Val Lys Lys
                 275                 280                 285

 Met Leu Arg Ser His Gln Val Ser Val Thr Leu Asp Pro Asp Thr
                 290                 295                 300

 Ala His His Glu Leu Ile Leu Ser Glu Asp Arg Arg Gln Val Thr
                 305                 310                 315

 Arg Gly Tyr Thr Gln Glu Asn Gln Asp Thr Ser Ser Arg Arg Phe
                 320                 325                 330

 Thr Ala Phe Pro Cys Val Leu Gly Cys Glu Gly Phe Thr Ser Gly
                 335                 340                 345

 Arg Arg Tyr Phe Glu Val Asp Val Gly Glu Gly Thr Gly Trp Asp
                 350                 355                 360

 Leu Gly Val Cys Met Glu Asn Val Gln Arg Gly Thr Gly Met Lys
                 365                 370                 375

 Gln Glu Pro Gln Ser Gly Phe Trp Thr Leu Arg Leu Cys Lys Lys
                 380                 385                 390

 Lys Gly Tyr Val Ala Leu Thr Ser Pro Pro Thr Ser Leu His Leu
                 395                 400                 405

 His Glu Gln Pro Leu Leu Val Gly Ile Phe Leu Asp Tyr Glu Ala
                 410                 415                 420

 Gly Val Val Ser Phe Tyr Asn Gly Asn Thr Gly Cys His Ile Phe
                 425                 430                 435

 Thr Phe Pro Lys Ala Ser Phe Ser Asp Thr Leu Arg Pro Tyr Phe
                 440                 445                 450

 Gln Val Tyr Gln Tyr Ser Pro Leu Phe Leu Pro Pro Pro Gly Asp
                 455                 460                 465

<210> 925
<211> 3615
<212> DNA
<213> Homo sapien

<400> 925
 cggtcctgcc tcgctgcctt cagtccctag tgtctgggtc cccgccctcc 50

 agccgccttt gagtcgtgcc tgggtcctcg cccttgcctc agaaccgcga 100

 agaaaggaag ctcgcgtgtt tgctagaaaa cctagttggg agtgcgaggc 150

 agagaacgtt cagcaccttt gttcctcccg aaccctcggg acagaggcag 200

 ggttctgagg gcagggattc cccctcgtct tggccccacc gcccgggctg 250

 ggcactaaac tcgggccgcg gcggggcgag cgaggcgggc tccggaggga 300

 gctgacgcct gatgatggcg cagtccaaca tgtttaccgt ggctgatgtg 350

 ttgagtcaag atgaactgcg caaaaagcta taccagacgt ttaaggatcg 400

 gggtatactg gatacactca agacacaact tcgaaaccag ctaattcatg 450

 agttgatgca ccctgtattg agtggagaac tgcagcctcg gtccatttca 500

 gtagaaggga gctccctctt aataggcgcc tctaactctt tagtggcaga 550

 tcacttacaa agatgtggct atgaatattc actttctgtt ttctttccag 600

 aaagtggttt ggcaaaagaa aaggtattta ctatgcagga tctattacaa 650

 ctcattaaaa tcaaccctac ttccagtctc tacaaatcac tggtttcagg 700

 atctgataaa gaaaatcaaa aaggttttct tatgcatttt ttaaaagaat 750

 tggcagaata tcatcaagct aaagagagtt gtaatatgga aactcagaca 800

 agttcgacat ttaacagaga ttctctggct gagaagcttc agcttattga 850

 tgatcagttt gcagatgctt accctcagcg tatcaagttc gaatctttag 900

 aaataaagct aaatgagtat aagagagaaa tagaagagca acttcgggca 950

 gaaatgtgtc aaaagttgaa gttttttaaa gataccgaga tagcaaaaat 1000

 taaaatggaa gcaaaaaaaa agtatgaaaa ggagttaacc atgttccaga 1050

 atgattttga aaaagcttgt caagcaaaat ctgaagctct cgttcttcgg 1100

 gaaaagagta cccttgaaag aattcacaag caccaagaga ttgaaacaaa 1150

 agaaatttat gctcaaaggc aacttttact aaaagatatg gatttgctaa 1200

 gaggaagaga agcagagctg aagcaaagag ttgaagcttt tgaattgaac 1250

 cagaagctcc aggaagaaaa acataaaagc ataactgagg cacttaggag 1300

 acaggagcag aatataaaga gttttgagga gacctatgac cgaaagctca 1350

 agaatgaact tctaaagtat caacttgaac tgaaggatga ctacatcatt 1400

 agaactaatc gactgattga agatgaaagg aagaataaag aaaaagctgt 1450

 tcatttgcaa gaggagctca tagctattaa ttcaaaaaag gaggaactca 1500

 atcaatctgt aaatcgtgtg aaagaacttg agcttgaatt agagtctgtc 1550

 aaagcccagt ctttggcaat aacaaaacaa aaccatatgc tgaatgaaaa 1600

 ggttaaagag atgagtgatt attcactact aaaagaagag aaactggagc 1650

 ttctggcaca aaataaatta cttaaacaac aactggaaga gagtagaaat 1700

 gaaaacctgc gtctcctaaa ccgcctagct cagccggctc ctgaacttgc 1750

 agtctttcag aaagaactac ggaaagccga aaaggctata gtggttgagc 1800

 atgaggagtt cgaaagctgc aggcaagctc tgcacaaaca actgcaagac 1850

 gaaattgagc attctgcaca gctgaaggcc cagattctag gttacaaagc 1900

 ttctgtaaag agtttaacta ctcaggttgc cgatttaaaa ttgcaactga 1950

 agcaaactca gacagcccta gagaatgaag tgtactgcaa tccaaagcag 2000

 tctgtgatcg atcgttctgt caatggatta ataaatggca atgtggtgcc 2050

 ttgcaatggt gagataagtg gggatttctt gaacaatcct tttaaacagg 2100

 aaaacgttct agcacgtatg gttgcatcaa ggatcacaaa ttatccaact 2150

 gcatgggtgg agggtagttc ccctgattct gaccttgagt ttgtagccaa 2200

 tactaaggca agggtcaaag agcttcagca agaggccgaa cgcttggaaa 2250

 aggctttcag aagttaccat cggagagtca ttaaaaactc tgccaaaagc 2300

 ccactagcag caaagagccc accatctctg cacttgctgg aagccttcaa 2350

 aaacattact tccagttccc cggaaagaca tatttttgga gaggacagag 2400

 ttgtctctga gcagcctcaa gtgggcacac ttgaagaaag gaatgacgtc 2450

 gtggaagcac tgacaggcag tgcagcctcg aggctccgcg ggggcacttc 2500

 ctccagacgc ctctcttcca caccccttcc aaaagcaaaa agaagcctcg 2550

 aaagtgaaat gtatctggaa ggtctgggca gatcacacat tgcttccccc 2600

 agtccttgtc ctgacagaat gcccctacca tcacccactg agtctaggca 2650

 cagcctctcc atccctcctg tctccagccc tccggagcag aaagtgggtc 2700

 tttatcgaag acaaactgaa cttcaagaca aaagtgaatt ttcagatgtg 2750

 gacaagctag cttttaagga taatgaggag tttgaatcat cttttgaatc 2800

 tgcagggaac atgccaaggc agttggaaat gggcgggctt tctcctgccg 2850

 gggatatgtc tcatgtggac gctgctgcag ctgctgtgcc cctctcatat 2900

 cagcacccaa gtgtagatca gaaacaaatt gaagaacaaa aggaagaaga 2950

 aaaaatacgg gaacagcaag tgaaagaacg aaggcagaga gaagaaagaa 3000

 ggcagagtaa cctacaagaa gttttagaaa gggaacgaag agaactagaa 3050

 aaactgtatc aggaaaggaa gatgattgaa gaatcactga agattaaaat 3100

 aaaaaaggaa ttagaaatgg aaaatgaatt agaaatgagt aatcaagaaa 3150

 taaaagacaa atctgctcac agtgaaaatc ctttagagaa atacatgaaa 3200

 atcatccagc aggagcaaga ccaggagtcg gcagataaga gctcaaaaaa 3250

 gatggtccaa gaaggctccc tagtggacac gctgcaatct agtgacaaag 3300

 tcgaaagttt aacaggcttt tctcatgaag aactagacga ctcttggtaa 3350

 ccatgtttgc tgcccagctt ctaacttaca taccgtgaga agttacgtaa 3400

 catttactcc tttgtaaatg tttccctatc atcagacaaa actcaataaa 3450

 aatgtgtgta atccaatgtg ggtttttttt tccataatta attttgatac 3500

 catagtgtgt gaaccaagaa taatctagtc acgtgaaacc tcttctccag 3550

 tcatagtatt tctcattcat tataataaaa gtaactggct tttaaaaaaa 3600

 aaaaaaaaaa aaaaa 3615

<210> 926
<211> 1012
<212> PRT
<213> Homo sapien

<400> 926
 Met Met Ala Gln Ser Asn Met Phe Thr Val Ala Asp Val Leu Ser
   1               5                  10                  15

 Gln Asp Glu Leu Arg Lys Lys Leu Tyr Gln Thr Phe Lys Asp Arg
                  20                  25                  30

 Gly Ile Leu Asp Thr Leu Lys Thr Gln Leu Arg Asn Gln Leu Ile
                  35                  40                  45

 His Glu Leu Met His Pro Val Leu Ser Gly Glu Leu Gln Pro Arg
                  50                  55                  60

 Ser Ile Ser Val Glu Gly Ser Ser Leu Leu Ile Gly Ala Ser Asn
                  65                  70                  75

 Ser Leu Val Ala Asp His Leu Gln Arg Cys Gly Tyr Glu Tyr Ser
                  80                  85                  90

 Leu Ser Val Phe Phe Pro Glu Ser Gly Leu Ala Lys Glu Lys Val
                  95                 100                 105

 Phe Thr Met Gln Asp Leu Leu Gln Leu Ile Lys Ile Asn Pro Thr
                 110                 115                 120

 Ser Ser Leu Tyr Lys Ser Leu Val Ser Gly Ser Asp Lys Glu Asn
                 125                 130                 135

 Gln Lys Gly Phe Leu Met His Phe Leu Lys Glu Leu Ala Glu Tyr
                 140                 145                 150

 His Gln Ala Lys Glu Ser Cys Asn Met Glu Thr Gln Thr Ser Ser
                 155                 160                 165

 Thr Phe Asn Arg Asp Ser Leu Ala Glu Lys Leu Gln Leu Ile Asp
                 170                 175                 180

 Asp Gln Phe Ala Asp Ala Tyr Pro Gln Arg Ile Lys Phe Glu Ser
                 185                 190                 195

 Leu Glu Ile Lys Leu Asn Glu Tyr Lys Arg Glu Ile Glu Glu Gln
                 200                 205                 210

 Leu Arg Ala Glu Met Cys Gln Lys Leu Lys Phe Phe Lys Asp Thr
                 215                 220                 225

 Glu Ile Ala Lys Ile Lys Met Glu Ala Lys Lys Lys Tyr Glu Lys
                 230                 235                 240

 Glu Leu Thr Met Phe Gln Asn Asp Phe Glu Lys Ala Cys Gln Ala
                 245                 250                 255

 Lys Ser Glu Ala Leu Val Leu Arg Glu Lys Ser Thr Leu Glu Arg
                 260                 265                 270

 Ile His Lys His Gln Glu Ile Glu Thr Lys Glu Ile Tyr Ala Gln
                 275                 280                 285

 Arg Gln Leu Leu Leu Lys Asp Met Asp Leu Leu Arg Gly Arg Glu
                 290                 295                 300

 Ala Glu Leu Lys Gln Arg Val Glu Ala Phe Glu Leu Asn Gln Lys
                 305                 310                 315

 Leu Gln Glu Glu Lys His Lys Ser Ile Thr Glu Ala Leu Arg Arg
                 320                 325                 330

 Gln Glu Gln Asn Ile Lys Ser Phe Glu Glu Thr Tyr Asp Arg Lys
                 335                 340                 345

 Leu Lys Asn Glu Leu Leu Lys Tyr Gln Leu Glu Leu Lys Asp Asp
                 350                 355                 360

 Tyr Ile Ile Arg Thr Asn Arg Leu Ile Glu Asp Glu Arg Lys Asn
                 365                 370                 375

 Lys Glu Lys Ala Val His Leu Gln Glu Glu Leu Ile Ala Ile Asn
                 380                 385                 390

 Ser Lys Lys Glu Glu Leu Asn Gln Ser Val Asn Arg Val Lys Glu
                 395                 400                 405

 Leu Glu Leu Glu Leu Glu Ser Val Lys Ala Gln Ser Leu Ala Ile
                 410                 415                 420

 Thr Lys Gln Asn His Met Leu Asn Glu Lys Val Lys Glu Met Ser
                 425                 430                 435

 Asp Tyr Ser Leu Leu Lys Glu Glu Lys Leu Glu Leu Leu Ala Gln
                 440                 445                 450

 Asn Lys Leu Leu Lys Gln Gln Leu Glu Glu Ser Arg Asn Glu Asn
                 455                 460                 465

 Leu Arg Leu Leu Asn Arg Leu Ala Gln Pro Ala Pro Glu Leu Ala
                 470                 475                 480

 Val Phe Gln Lys Glu Leu Arg Lys Ala Glu Lys Ala Ile Val Val
                 485                 490                 495

 Glu His Glu Glu Phe Glu Ser Cys Arg Gln Ala Leu His Lys Gln
                 500                 505                 510

 Leu Gln Asp Glu Ile Glu His Ser Ala Gln Leu Lys Ala Gln Ile
                 515                 520                 525

 Leu Gly Tyr Lys Ala Ser Val Lys Ser Leu Thr Thr Gln Val Ala
                 530                 535                 540

 Asp Leu Lys Leu Gln Leu Lys Gln Thr Gln Thr Ala Leu Glu Asn
                 545                 550                 555

 Glu Val Tyr Cys Asn Pro Lys Gln Ser Val Ile Asp Arg Ser Val
                 560                 565                 570

 Asn Gly Leu Ile Asn Gly Asn Val Val Pro Cys Asn Gly Glu Ile
                 575                 580                 585

 Ser Gly Asp Phe Leu Asn Asn Pro Phe Lys Gln Glu Asn Val Leu
                 590                 595                 600

 Ala Arg Met Val Ala Ser Arg Ile Thr Asn Tyr Pro Thr Ala Trp
                 605                 610                 615

 Val Glu Gly Ser Ser Pro Asp Ser Asp Leu Glu Phe Val Ala Asn
                 620                 625                 630

 Thr Lys Ala Arg Val Lys Glu Leu Gln Gln Glu Ala Glu Arg Leu
                 635                 640                 645

 Glu Lys Ala Phe Arg Ser Tyr His Arg Arg Val Ile Lys Asn Ser
                 650                 655                 660

 Ala Lys Ser Pro Leu Ala Ala Lys Ser Pro Pro Ser Leu His Leu
                 665                 670                 675

 Leu Glu Ala Phe Lys Asn Ile Thr Ser Ser Ser Pro Glu Arg His
                 680                 685                 690

 Ile Phe Gly Glu Asp Arg Val Val Ser Glu Gln Pro Gln Val Gly
                 695                 700                 705

 Thr Leu Glu Glu Arg Asn Asp Val Val Glu Ala Leu Thr Gly Ser
                 710                 715                 720

 Ala Ala Ser Arg Leu Arg Gly Gly Thr Ser Ser Arg Arg Leu Ser
                 725                 730                 735

 Ser Thr Pro Leu Pro Lys Ala Lys Arg Ser Leu Glu Ser Glu Met
                 740                 745                 750

 Tyr Leu Glu Gly Leu Gly Arg Ser His Ile Ala Ser Pro Ser Pro
                 755                 760                 765

 Cys Pro Asp Arg Met Pro Leu Pro Ser Pro Thr Glu Ser Arg His
                 770                 775                 780

 Ser Leu Ser Ile Pro Pro Val Ser Ser Pro Pro Glu Gln Lys Val
                 785                 790                 795

 Gly Leu Tyr Arg Arg Gln Thr Glu Leu Gln Asp Lys Ser Glu Phe
                 800                 805                 810

 Ser Asp Val Asp Lys Leu Ala Phe Lys Asp Asn Glu Glu Phe Glu
                 815                 820                 825

 Ser Ser Phe Glu Ser Ala Gly Asn Met Pro Arg Gln Leu Glu Met
                 830                 835                 840

 Gly Gly Leu Ser Pro Ala Gly Asp Met Ser His Val Asp Ala Ala
                 845                 850                 855

 Ala Ala Ala Val Pro Leu Ser Tyr Gln His Pro Ser Val Asp Gln
                 860                 865                 870

 Lys Gln Ile Glu Glu Gln Lys Glu Glu Glu Lys Ile Arg Glu Gln
                 875                 880                 885

 Gln Val Lys Glu Arg Arg Gln Arg Glu Glu Arg Arg Gln Ser Asn
                 890                 895                 900

 Leu Gln Glu Val Leu Glu Arg Glu Arg Arg Glu Leu Glu Lys Leu
                 905                 910                 915

 Tyr Gln Glu Arg Lys Met Ile Glu Glu Ser Leu Lys Ile Lys Ile
                 920                 925                 930

 Lys Lys Glu Leu Glu Met Glu Asn Glu Leu Glu Met Ser Asn Gln
                 935                 940                 945

 Glu Ile Lys Asp Lys Ser Ala His Ser Glu Asn Pro Leu Glu Lys
                 950                 955                 960

 Tyr Met Lys Ile Ile Gln Gln Glu Gln Asp Gln Glu Ser Ala Asp
                 965                 970                 975

 Lys Ser Ser Lys Lys Met Val Gln Glu Gly Ser Leu Val Asp Thr
                 980                 985                 990

 Leu Gln Ser Ser Asp Lys Val Glu Ser Leu Thr Gly Phe Ser His
                 995                1000                1005

 Glu Glu Leu Asp Asp Ser Trp
                1010

<210> 927
<211> 1922
<212> DNA
<213> Homo sapien

<400> 927
 gcccctttct ttctcctcgt cggcccgaga gcaggaacac gataacgaag 50

 gaggcccaac ttcattcaat aaggagcctg acggatttat cccagacggt 100

 agaacaaaag gaagaatatt gatggatttt aaaccagagt ttttaaagag 150

 cttgagaata cggggaaatt aatttgttct cctacacaca tagatagggt 200

 aaggttgttt ctgatgcagc tgagaaaaat gcagaccgtc aaaaaggagc 250

 aggcgtctct tgatgccagt agcaatgtgg acaagatgat ggtccttaat 300

 tctgctttaa cggaagtgtc agaagactcc acaacaggtg aggacgtgct 350

 tctcagtgaa ggaagtgtgg ggaagaacaa atcttctgca tgtcggagga 400

 aacgggaatt cattcctgat gaaaagaaag atgctatgta ttgggaaaaa 450

 aggcggaaaa ataatgaagc tgccaaaaga tctcgtgaga agcgtcgact 500

 gaatgacctg gttttagaga acaaactaat tgcactggga gaagaaaacg 550

 ccactttaaa agctgagctg ctttcactaa aattaaagtt tggtttaatt 600

 agctccacag catatgctca agagattcag aaactcagta attctacagc 650

 tgtgtacttt caagattacc agacttccaa atccaatgtg agttcatttg 700

 tggacgagca cgaaccctcg atggtgtcaa gtagttgtat ttctgtcatt 750

 aaacactctc cacaaagctc gctgtccgat gtttcagaag tgtcctcagt 800

 agaacacacg caggagagct ctgtgcaggg aagctgcaga agtcctgaaa 850

 acaagttcca gattatcaag caagagccga tggaattaga gagctacaca 900

 agggagccaa gagatgaccg aggctcttac acagcgtcca tctatcaaaa 950

 ctatatgggg aattctttct ctgggtactc acactctccc ccactactgc 1000

 aagtcaaccg atcctccagc aactccccgg gaacgtcgga aactgatgat 1050

 ggtgtggtag gaaagtcatc tgatggagaa gacgagcaac aggtccccaa 1100

 gggccccatc cattctccag ttgaactcaa gcatgtgcat gcaactgtgg 1150

 ttaaagttcc agaagtgaat tcctctgcct tgccacacaa gctccggatc 1200

 aaagccaaag ccatgcagat caaagtagaa gcctttgata atgaatttga 1250

 ggccacgcaa aaactttcct cacctattga catgacatct aaaagacatt 1300

 tcgaactcga aaagcatagt gccccaagta tggtacattc ttctcttact 1350

 cctttctcag tgcaagtgac taacattcaa gattggtctc tcaaatcgga 1400

 gcactggcat caaaaagaac tgagtggcaa aactcagaat agtttcaaaa 1450

 ctggagttgt tgaaatgaaa gacagtggct acaaagtttc tgacccagag 1500

 aacttgtatt tgaagcaggg gatagcaaac ttatctgcag aggttgtctc 1550

 actcaagaga cttatagcca cacaaccaat ctctgcttca gactctgggt 1600

 aaattactac tgagtaagag ctgggcattt agaaagatgt catttgcaat 1650

 agagcagtcc attttgtatt atgctgaatt ttcactggac ctgtgatgtc 1700

 atttcactgt gatgtgcaca tgttgtctgt ttggtgtctt tttgtgcaca 1750

 gattatgatg aagattagat tgtgttatca ctctgcctgt gtatagtcag 1800

 atagtccatg cgaaggctgt atatattgaa cattattttt gttgttctat 1850

 tataaagtgt gtaagttacc agtttcaata aaggattggt gacaaacaca 1900

 gaaaaaaaaa aaaaaaaaaa aa 1922

<210> 928
<211> 462
<212> PRT
<213> Homo sapien

<400> 928
 Met Gln Leu Arg Lys Met Gln Thr Val Lys Lys Glu Gln Ala Ser
   1               5                  10                  15

 Leu Asp Ala Ser Ser Asn Val Asp Lys Met Met Val Leu Asn Ser
                  20                  25                  30

 Ala Leu Thr Glu Val Ser Glu Asp Ser Thr Thr Gly Glu Asp Val
                  35                  40                  45

 Leu Leu Ser Glu Gly Ser Val Gly Lys Asn Lys Ser Ser Ala Cys
                  50                  55                  60

 Arg Arg Lys Arg Glu Phe Ile Pro Asp Glu Lys Lys Asp Ala Met
                  65                  70                  75

 Tyr Trp Glu Lys Arg Arg Lys Asn Asn Glu Ala Ala Lys Arg Ser
                  80                  85                  90

 Arg Glu Lys Arg Arg Leu Asn Asp Leu Val Leu Glu Asn Lys Leu
                  95                 100                 105

 Ile Ala Leu Gly Glu Glu Asn Ala Thr Leu Lys Ala Glu Leu Leu
                 110                 115                 120

 Ser Leu Lys Leu Lys Phe Gly Leu Ile Ser Ser Thr Ala Tyr Ala
                 125                 130                 135

 Gln Glu Ile Gln Lys Leu Ser Asn Ser Thr Ala Val Tyr Phe Gln
                 140                 145                 150

 Asp Tyr Gln Thr Ser Lys Ser Asn Val Ser Ser Phe Val Asp Glu
                 155                 160                 165

 His Glu Pro Ser Met Val Ser Ser Ser Cys Ile Ser Val Ile Lys
                 170                 175                 180

 His Ser Pro Gln Ser Ser Leu Ser Asp Val Ser Glu Val Ser Ser
                 185                 190                 195

 Val Glu His Thr Gln Glu Ser Ser Val Gln Gly Ser Cys Arg Ser
                 200                 205                 210

 Pro Glu Asn Lys Phe Gln Ile Ile Lys Gln Glu Pro Met Glu Leu
                 215                 220                 225

 Glu Ser Tyr Thr Arg Glu Pro Arg Asp Asp Arg Gly Ser Tyr Thr
                 230                 235                 240

 Ala Ser Ile Tyr Gln Asn Tyr Met Gly Asn Ser Phe Ser Gly Tyr
                 245                 250                 255

 Ser His Ser Pro Pro Leu Leu Gln Val Asn Arg Ser Ser Ser Asn
                 260                 265                 270

 Ser Pro Gly Thr Ser Glu Thr Asp Asp Gly Val Val Gly Lys Ser
                 275                 280                 285

 Ser Asp Gly Glu Asp Glu Gln Gln Val Pro Lys Gly Pro Ile His
                 290                 295                 300

 Ser Pro Val Glu Leu Lys His Val His Ala Thr Val Val Lys Val
                 305                 310                 315

 Pro Glu Val Asn Ser Ser Ala Leu Pro His Lys Leu Arg Ile Lys
                 320                 325                 330

 Ala Lys Ala Met Gln Ile Lys Val Glu Ala Phe Asp Asn Glu Phe
                 335                 340                 345

 Glu Ala Thr Gln Lys Leu Ser Ser Pro Ile Asp Met Thr Ser Lys
                 350                 355                 360

 Arg His Phe Glu Leu Glu Lys His Ser Ala Pro Ser Met Val His
                 365                 370                 375

 Ser Ser Leu Thr Pro Phe Ser Val Gln Val Thr Asn Ile Gln Asp
                 380                 385                 390

 Trp Ser Leu Lys Ser Glu His Trp His Gln Lys Glu Leu Ser Gly
                 395                 400                 405

 Lys Thr Gln Asn Ser Phe Lys Thr Gly Val Val Glu Met Lys Asp
                 410                 415                 420

 Ser Gly Tyr Lys Val Ser Asp Pro Glu Asn Leu Tyr Leu Lys Gln
                 425                 430                 435

 Gly Ile Ala Asn Leu Ser Ala Glu Val Val Ser Leu Lys Arg Leu
                 440                 445                 450

 Ile Ala Thr Gln Pro Ile Ser Ala Ser Asp Ser Gly
                 455                 460

<210> 929
<211> 2189
<212> DNA
<213> Homo sapien

<400> 929
 agcggggcgg aagtcggttc ccgtgacgcg gcgcgcccca agggccggct 50

 ccgttgaggg aagggagccc gcccggtggc ggctggggtc ggctgctggg 100

 aggaggtggt gggctggttc ggacgtgggt cgaggctgta gcaggactcc 150

 aggtgaggcc tgaggaccac tctgccctcc cgcggcccgg gctcgcgccg 200

 ggggccattt aatcccgaca gcttgcggcc tgacgtcgct gcggcctggc 250

 agtgaccacg tcggcgtccg gcccctcggc cggcgataga gttgcggcta 300

 aaatgaaagg acgcccagtt acatttgcat cgtagataaa gaaagagcat 350

 ttagtataag catgtccgaa atgttgcgtg ggatgtaggc atactaaaac 400

 cttattcgtg gcctgtctga aatccaaatg gagctgggta ttctgtgttt 450

 ttatttgcta aatctggcag ccgtacccgc ggccccgggc agggagggag 500

 cagctgggct cggccagacc ctgccggcgt ctggggggcc tgcgaagtgg 550

 aggggagacg ggcagccggg cagtggccgg cgttccccgg agctcggacc 600

 ggttggattg gactccgacg ctaccgctcc ctctgctgaa ctattccgga 650

 tgtaaaacac tagggatcgg agtttttctt ggttttttaa tctcattcta 700

 gtgaccgaga agcttgctgg cagtgcgctg atggatctgt gtgaataggc 750

 catttatttg acctcttcag taacactgtt ctaaccggct gaaactgctt 800

 tcttaggcat tttcttaaaa gcttggtggt taagagcacg gaatttcgag 850

 tcagatttcc aatcttggct ctatcactat cctcggagtc atggggcagt 900

 cacatcatcc ctgtctctgt aatggtagct gcccctggat aagtgttatt 950

 aggtgattca gaagggtggg ctgttgccct tgcctgaggt tgcagtctgc 1000

 ggttcccaag ccccaagacc cgcctcagaa ctaactgcat ttgcttttga 1050

 ctcctggcct ttctctaggg ttgggaagaa catggaaagt gacctccctg 1100

 ccaaataact cagaagagga gtgtcggtag ccaaatgttt cttcagaata 1150

 cgtgtaaaag aaatgttttt cttccatcta ggaagatgtt accgagtact 1200

 tcagtgaatt ccttagtgca ggggaacgga gtcttgaatt ccagggatgc 1250

 ggcaagacac acagccggag cgaaacgcta caaatatctg agaaggcttt 1300

 tccgctttcg gcaaatggac tttgaatttg ctgcctggca gatgctctac 1350

 ctgttcacat ccccacagag agtttacaga aattttcatt atcgaaaaca 1400

 gacgaaggac cagtgggcca gagatgaccc tgctttcttg gtcctgttaa 1450

 gtatctggct ctgtgtgtcc actataggat ttggctttgt gctggacatg 1500

 ggattctttg agacaataaa gcttctcctt tgggttgtac tcatagattg 1550

 tgtaggcgtt ggtcttctga tagcaacttt aatgtggttc atctctaaca 1600

 agtatttagt gaaacgacag agcagagact atgatgtgga atggggctat 1650

 gcttttgatg tgcatctcaa tgctttttat ccactcctgg tcattttgca 1700

 ttttatccag ctttttttca tcaaccatgt tatcctgaca gacacattta 1750

 ttggatattt agttggaaat accttatggt tggttgcagt tggctattat 1800

 atctatgtaa ctttcctggg atacagtgca ttgccatttt tgaaaaatac 1850

 agtaattctt ctgtatccat ttgcacctct gattctgctc tacgggcttt 1900

 ccctggcact gggatggaac ttcacccata ctctctgttc tttctataag 1950

 tacagagtga aataaaaagt gagaagaaga ttcaatcgta actgtgtcaa 2000

 cagtattgtg aagtgatcat ttcttgtaaa acttgtaaat aaactatcat 2050

 ctttgtagat atcttaaagg tgtaaagttt gcaaatttga agaaatatat 2100

 attaacactg tggtcaggta cattccttaa aactaattaa atgtacattt 2150

 ctataataaa tattttttaa actaaaaaaa aaaaaaaaa 2189

<210> 930
<211> 259
<212> PRT
<213> Homo sapien

<400> 930
 Met Leu Pro Ser Thr Ser Val Asn Ser Leu Val Gln Gly Asn Gly
   1               5                  10                  15

 Val Leu Asn Ser Arg Asp Ala Ala Arg His Thr Ala Gly Ala Lys
                  20                  25                  30

 Arg Tyr Lys Tyr Leu Arg Arg Leu Phe Arg Phe Arg Gln Met Asp
                  35                  40                  45

 Phe Glu Phe Ala Ala Trp Gln Met Leu Tyr Leu Phe Thr Ser Pro
                  50                  55                  60

 Gln Arg Val Tyr Arg Asn Phe His Tyr Arg Lys Gln Thr Lys Asp
                  65                  70                  75

 Gln Trp Ala Arg Asp Asp Pro Ala Phe Leu Val Leu Leu Ser Ile
                  80                  85                  90

 Trp Leu Cys Val Ser Thr Ile Gly Phe Gly Phe Val Leu Asp Met
                  95                 100                 105

 Gly Phe Phe Glu Thr Ile Lys Leu Leu Leu Trp Val Val Leu Ile
                 110                 115                 120

 Asp Cys Val Gly Val Gly Leu Leu Ile Ala Thr Leu Met Trp Phe
                 125                 130                 135

 Ile Ser Asn Lys Tyr Leu Val Lys Arg Gln Ser Arg Asp Tyr Asp
                 140                 145                 150

 Val Glu Trp Gly Tyr Ala Phe Asp Val His Leu Asn Ala Phe Tyr
                 155                 160                 165

 Pro Leu Leu Val Ile Leu His Phe Ile Gln Leu Phe Phe Ile Asn
                 170                 175                 180

 His Val Ile Leu Thr Asp Thr Phe Ile Gly Tyr Leu Val Gly Asn
                 185                 190                 195

 Thr Leu Trp Leu Val Ala Val Gly Tyr Tyr Ile Tyr Val Thr Phe
                 200                 205                 210

 Leu Gly Tyr Ser Ala Leu Pro Phe Leu Lys Asn Thr Val Ile Leu
                 215                 220                 225

 Leu Tyr Pro Phe Ala Pro Leu Ile Leu Leu Tyr Gly Leu Ser Leu
                 230                 235                 240

 Ala Leu Gly Trp Asn Phe Thr His Thr Leu Cys Ser Phe Tyr Lys
                 245                 250                 255

 Tyr Arg Val Lys


<210> 931
<211> 3906
<212> DNA
<213> Homo sapien

<400> 931
 ctggcgcgcg cacgcgcacg cgcacgccca ccgcgcggct tcccccgctc 50

 cccggtgctg aggagagagc gatccgaggg actgcgccgc ccggacggcc 100

 tgcagagcgc tgccatcatg agtgaaattc gtaaggacac cttgaaggcc 150

 attctgttgg agttagaatg tcattttaca tggaatttac ttaaggaaga 200

 cattgatctg tttgaggtag aagatacaat tgggcaacag cttgaatttc 250

 ttaccacaaa atctagactt gctctttata acctattggc ctatgtgaaa 300

 cacctaaaag gccaaaataa agacgccctt gagtgcttgg aacaagcaga 350

 agaaataatc cagcaagaac actcagacaa agaagaagta cgaagcctgg 400

 tcacttgggg aaactatgcc tgggtgtatt atcacatgga ccagcttgaa 450

 gaagctcaga agtatacagg taagataggg aatgtctgta agaaattgtc 500

 cagtccttct aactacaagt tggagtgtcc tgagactgac tgtgagaaag 550

 gctgggcact cttgaaattt ggaggaaagt attatcaaaa ggctaaagcg 600

 gcttttgaga aggctctgga agtggagcct gacaatccag aatttaacat 650

 cggctatgct atcacagtgt atcggctgga tgattctgat agagaagggt 700

 ctgtaaagag cttttctctg gggcctttga gaaaggctgt taccctgaac 750

 ccagataaca gctatattaa ggtttttctg gcactgaagc ttcaagatgt 800

 acatgcagaa gctgaagggg aaaagtatat tgaagaaatc ctggaccaaa 850

 tatcatccca gccttacgtc cttcgttatg cagccaagtt ctataggaga 900

 aaaaattcct ggaacaaagc tctcgaactt ttaaaaaagg ccttggaggt 950

 gacaccaact tcttctttcc tgcatcacca gatgggactt tgctacaggg 1000

 cacaaatgat ccaaatcaag aaggccacac acaacagacc taaaggaaag 1050

 gataaactaa aggttgatga gctgatttca tctgctatat ttcatttcaa 1100

 agcagccatg gaacgagact ctatgtttgc atttgcctac acagacctgg 1150

 ccaacatgta tgctgaagga ggccagtata gcaatgctga ggacattttc 1200

 cggaaagctc ttcgtctgga gaacataacc gatgatcaca aacatcagat 1250

 ccattaccac tatggccgct ttcaggaatt tcaccgtaaa tcagaaaata 1300

 ctgccatcca tcattattta gaagccttaa aggtcaaaga cagatcaccc 1350

 cttcgcacca aactgacaag tgctctgaag aaattgtcta ccaagagact 1400

 ttgtcacaat gctttagatg tgcagagttt aagtgcccta gggtttgttt 1450

 acaagctgga aggagaaaag aggcaagctg ctgagtacta tgagaaggca 1500

 caaaagatag atccagaaaa tgcagaattc ctgactgctc tctgtgagct 1550

 ccgactttcc atttaaatac atactctagg aaattagctc taagtttttc 1600

 ccttcatttt gggttctcct gtttgttttt tttttattat tttaatccct 1650

 tgtttattat agagctaata tttattgaat agttattgtg taccaagcat 1700

 tgtgctaaat actttatatg cattatgatg aatcttgtgc ggttttcttt 1750

 ctttttttct ttttaattaa aatactataa tccattgaga aatagcaata 1800

 ttctagctat tgtaacttct aaaaatggta tggccattag atctgtgctt 1850

 tttatctctg ctctttgaat ttctcatatt atatagtaaa tatattccta 1900

 cgtaaacctt tgatacctag atcaggaata ctcttccagg agtacaaaat 1950

 tacattattg atagttaagc tcttaattgt gtagcttgca aaagacagca 2000

 ctttttagtt acagatgttt tgactttgat gaggatattt agctatcaat 2050

 ctaatagtca cctaaaatat cttttttgtt ggaaaaaagt ttataataaa 2100

 aaagtttgtc atctctagtg acttcaataa agaaaaaact agaagaggag 2150

 aaaaaggatt tcctcaaatt ttaaatatgt aacttcaggg attcaatccc 2200

 caaatgttta ttaagtagct agaaataatt atgtggaaaa aaatgaataa 2250

 tggaaaatag tgagtctcaa attgtttttt tttaactaaa atctgcaatg 2300

 aatctagatg caattaattt tattccttcc aactaaaatt acaatatttt 2350

 taggttaaaa ttattgagat ataaagcagc cattgggaaa ttgggagaaa 2400

 tgataaacaa atggaaaaag aagatgtccc taacctacac ccatagatta 2450

 ccaaggtttc agtgtactag ttttgaatct gttctgaatg gagtttttat 2500

 accctcaatt tctggccttt ggctatttta gcatttcaaa gtgacttcta 2550

 tgaagctttt tttttaatgt gaaattttca gaatgttgtt tttttcatgt 2600

 agatactcca ggaagagtta agcactgctt tcagttttaa tatccacctt 2650

 gaggggtcgc tgcttgaggg ctcttatccc aggggacttt ttaattcgga 2700

 tgttacttaa tgtggcttct ctaatgtagt ttctttgatt accgactaca 2750

 caattatgta ccatcacagt attagtggaa aagtaccatg tgatttaatt 2800

 ctccattcct ccaatgtaac tcttaaaatt attatgtatg tgtatgtgtt 2850

 ttactttttg ttttttatca tctttaaaat ttctattatg gtttgattat 2900

 tataaaaata atgaattctc actgtaaatt tcaaaaaaaa aattacaaaa 2950

 gtatgtgaat ttaaaaatga gagcagtccc ctcaccctac cacagttcca 3000

 caccctcaag gtaaacttat aacttataat ttgatatgta aacttccaga 3050

 tcttttttct atgcgtaatc agacatacat atatactgca gtgtatctca 3100

 cgtattaatt tttaaaaatc ttttgtttta cttaattctg tttttattat 3150

 tattattatt ttgtttgatc tattaaggaa gaacaaggaa gggaatgatc 3200

 tttactcaag aatttcagaa agtcagcact gaagtcctga cctatcagta 3250

 gacacatttg tccctttcag atattttagg atattctagc aaagcaggcc 3300

 atttctccca cctgaaagta cataacttct atcacttgcc acataattaa 3350

 aagaactcac attaagcggt tactcagaca gttaatcata gaaaagatta 3400

 tttgcttcat cagttcatag aaaagattat ttgcttcatc agttaacttg 3450

 tttttataaa tcagggcctg tgttcataca cagaaggggc ctgagatttc 3500

 tgcactttaa acaagctcct cctaggtgag gatgctgtgg ctgttctaat 3550

 tacattttga gtagtaaggt ctacagcatt gttcctcaaa cttggctacg 3600

 tattggaatc acctaaaaag ttaaaacaaa acatggatgt ctgggtcccg 3650

 ccccatagag aatgacttaa ttggcatggg gtgcagtcca ggcatcatga 3700

 tttttagatt tcccagttgg aacttgtgca gcaaagtttg ggagctactg 3750

 atggacatgt gaaaagtaag tataaatgga ataaaattaa ttaggctaat 3800

 aggcttaacc caggaaatcc taagttcctt gaatatccag tttgcatttg 3850

 ggactcctca tcatatactt ggtatataat actctaataa aagctgcctg 3900

 agttga 3906

<210> 932
<211> 482
<212> PRT
<213> Homo sapien

<400> 932
 Met Ser Glu Ile Arg Lys Asp Thr Leu Lys Ala Ile Leu Leu Glu
   1               5                  10                  15

 Leu Glu Cys His Phe Thr Trp Asn Leu Leu Lys Glu Asp Ile Asp
                  20                  25                  30

 Leu Phe Glu Val Glu Asp Thr Ile Gly Gln Gln Leu Glu Phe Leu
                  35                  40                  45

 Thr Thr Lys Ser Arg Leu Ala Leu Tyr Asn Leu Leu Ala Tyr Val
                  50                  55                  60

 Lys His Leu Lys Gly Gln Asn Lys Asp Ala Leu Glu Cys Leu Glu
                  65                  70                  75

 Gln Ala Glu Glu Ile Ile Gln Gln Glu His Ser Asp Lys Glu Glu
                  80                  85                  90

 Val Arg Ser Leu Val Thr Trp Gly Asn Tyr Ala Trp Val Tyr Tyr
                  95                 100                 105

 His Met Asp Gln Leu Glu Glu Ala Gln Lys Tyr Thr Gly Lys Ile
                 110                 115                 120

 Gly Asn Val Cys Lys Lys Leu Ser Ser Pro Ser Asn Tyr Lys Leu
                 125                 130                 135

 Glu Cys Pro Glu Thr Asp Cys Glu Lys Gly Trp Ala Leu Leu Lys
                 140                 145                 150

 Phe Gly Gly Lys Tyr Tyr Gln Lys Ala Lys Ala Ala Phe Glu Lys
                 155                 160                 165

 Ala Leu Glu Val Glu Pro Asp Asn Pro Glu Phe Asn Ile Gly Tyr
                 170                 175                 180

 Ala Ile Thr Val Tyr Arg Leu Asp Asp Ser Asp Arg Glu Gly Ser
                 185                 190                 195

 Val Lys Ser Phe Ser Leu Gly Pro Leu Arg Lys Ala Val Thr Leu
                 200                 205                 210

 Asn Pro Asp Asn Ser Tyr Ile Lys Val Phe Leu Ala Leu Lys Leu
                 215                 220                 225

 Gln Asp Val His Ala Glu Ala Glu Gly Glu Lys Tyr Ile Glu Glu
                 230                 235                 240

 Ile Leu Asp Gln Ile Ser Ser Gln Pro Tyr Val Leu Arg Tyr Ala
                 245                 250                 255

 Ala Lys Phe Tyr Arg Arg Lys Asn Ser Trp Asn Lys Ala Leu Glu
                 260                 265                 270

 Leu Leu Lys Lys Ala Leu Glu Val Thr Pro Thr Ser Ser Phe Leu
                 275                 280                 285

 His His Gln Met Gly Leu Cys Tyr Arg Ala Gln Met Ile Gln Ile
                 290                 295                 300

 Lys Lys Ala Thr His Asn Arg Pro Lys Gly Lys Asp Lys Leu Lys
                 305                 310                 315

 Val Asp Glu Leu Ile Ser Ser Ala Ile Phe His Phe Lys Ala Ala
                 320                 325                 330

 Met Glu Arg Asp Ser Met Phe Ala Phe Ala Tyr Thr Asp Leu Ala
                 335                 340                 345

 Asn Met Tyr Ala Glu Gly Gly Gln Tyr Ser Asn Ala Glu Asp Ile
                 350                 355                 360

 Phe Arg Lys Ala Leu Arg Leu Glu Asn Ile Thr Asp Asp His Lys
                 365                 370                 375

 His Gln Ile His Tyr His Tyr Gly Arg Phe Gln Glu Phe His Arg
                 380                 385                 390

 Lys Ser Glu Asn Thr Ala Ile His His Tyr Leu Glu Ala Leu Lys
                 395                 400                 405

 Val Lys Asp Arg Ser Pro Leu Arg Thr Lys Leu Thr Ser Ala Leu
                 410                 415                 420

 Lys Lys Leu Ser Thr Lys Arg Leu Cys His Asn Ala Leu Asp Val
                 425                 430                 435

 Gln Ser Leu Ser Ala Leu Gly Phe Val Tyr Lys Leu Glu Gly Glu
                 440                 445                 450

 Lys Arg Gln Ala Ala Glu Tyr Tyr Glu Lys Ala Gln Lys Ile Asp
                 455                 460                 465

 Pro Glu Asn Ala Glu Phe Leu Thr Ala Leu Cys Glu Leu Arg Leu
                 470                 475                 480

 Ser Ile


<210> 933
<211> 5170
<212> DNA
<213> Homo sapien

<400> 933
 gtttcctgtc gccgtcgttg cccgggccat ggcgacctgc atttggctgc 50

 ggagctgtgg ggcccggcgc ctcgggtcga cgtttccagg ctgccgcctc 100

 cgcccccgcg ccggcggcct ggtccctgcc tccgggcctg cgcccggccc 150

 ggcccagctc cgctgctacg ctgggcgcct ggcgggcctc tctgcggcgc 200

 tgctgcgcac cgacagcttc gtgggcggcc gctggctccc ggccgccgcc 250

 accttccccg tgcaagaccc ggccagcggc gccgctctgg gcatggtagc 300

 cgactgcggg gtgcgagagg cccgcgccgc cgtgcgcgct gcctacgagg 350

 ctttctgccg ctggagggag gtctccgcca aggagaggag ttcattactt 400

 cggaagtggt acaatttaat gatacaaaat aaggatgacc ttgccagaat 450

 aatcacagct gaaagtggaa agccactgaa ggaggcacat ggagaaattc 500

 tctattccgc ctttttccta gagtggttct ctgaggaagc ccgccgtgtt 550

 tacggagaca ttatccacac cccggcaaag gacaggcggg ccctggtcct 600

 caagcagccc ataggcgtgg ctgcagtcat caccccgtgg aatttcccca 650

 gtgccatgat cacccggaag gtgggggccg ccctggcagc cggctgtact 700

 gtcgtggtga agcctgccga agacacgccc ttctccgccc tggccctggc 750

 tgaggtaaat cagggatttc ttcttgattt ggatccattg ttgcttgcaa 800

 gccaggctgg gattccttca ggtgtataca atgttattcc ctgttctcga 850

 aagaatgcca aggaagtagg ggaggcaatt tgtactgatc ctctggtgtc 900

 caaaatttcc tttactggtt caacaactac aggaaagatc ctgttgcacc 950

 acgcagcaaa ctctgtgaaa agggtctcta tggagctggg cggccttgct 1000

 ccatttatag tatttgacag tgccaacgtg gaccaggctg tagcaggggc 1050

 catggcatct aaatttagga acactggaca gacttgtgtt tgctcaaacc 1100

 aattcttggt gcaaaggggc atccatgatg cctttgtaaa agcattcgcc 1150

 gaggccatga agaagaacct gcgcgtaggt aatggatttg aggaaggaac 1200

 tactcagggc ccattaatta atgaaaaagc ggtagaaaag gtggagaaac 1250

 aggtgaatga tgccgtttct aaaggtgcca ccgttgtgac aggtggaaaa 1300

 cgacaccaac ttggaaaaaa tttctttgag cctaccctgc tgtgcaatgt 1350

 cacccaggac atgctgtgca ctcatgaaga gactttcggg cctctggcac 1400

 cagttatcaa gttcgataca gaggaggagg ctatagcaat cgctaacgca 1450

 gctgatgttg ggttagcagg ttatttttac tctcaagacc cagcccagat 1500

 ctggagagtg gcagagcagc tggaagtggg catggttggc gtcaacgaag 1550

 gattaatttc ctctgtggag tgcccttttg gtggagtgaa gcagtccggc 1600

 cttgggcgag aggggtccaa gtatggcatt gatgagtatc tggaactcaa 1650

 gtatgtgtgt tacgggggct tgtaggattc tttggttctt taaaaaaatt 1700

 taaaaggaga cttatctaca tatataggta catgccatcc attattttaa 1750

 ataaactaat aggttttcag aattatgaat ttttcagaac tcatccagtc 1800

 cttgtaatct taaacagatg caaatcctac ccctgccctt aatgtaacta 1850

 gggaccaata tgtgccacgt gcctgtggct gcagactccc agagaaccag 1900

 cactgggttt acagaatgag gccctggctc cccaccacag ccccagctgc 1950

 ctcagagcag gcacagcaca aggcaggccc agccccatgg gccgtcacaa 2000

 aggcttgatc actgcctggg cagtggcaca accatccccc atgtcgctac 2050

 agaacatggg cccagagcac cttgaaggag acccttgact gtgactggca 2100

 ggcaggtgag gggcacagca cccctccccg gcatctgcca gctcagcaca 2150

 gaagacaccg aatgtgcatc tggaggtgtt gcggcagagg tttgagtgaa 2200

 ccctctttca aagacaataa atagcacaga attgtccgtg cttctgtgag 2250

 gcacgaagga gcacctctcc ctattcctga accatatttt aattgatgcc 2300

 tttattgtcc caaatttacc acttaaagaa ttctattttc atttctgtcc 2350

 tgtttgccac ttcatttcat ttccttgagt aaatgagctg aagtgtaaag 2400

 caaagaatag cagaagcagc ttggtaggat ggaaggcacg cagtggcatg 2450

 gcctggctcc ttccctgagt ggccttgttg ccttgggcgt gtgttcagca 2500

 cctcccatcc catggataca gtggagattc catacaggcc ttacttagct 2550

 ccttgcgata ctgtgagcca gagagaaagt aaaagcactt cacaaaaaaa 2600

 tgaaaattct aaggacatac aagagccatt gttacgagca gcaccgccca 2650

 gcccttcctt gcctactgtc agtggctttg ccaagatggg aggaggccag 2700

 tgcccacttg cccaccgacc tgagcctgag taagtggctg tcacctgagc 2750

 ctgttctttc tgtcctggtg tggtgctgct ccctcacctc caaaagagca 2800

 aaagtacttt caccacagtc aacccaaaag ggaaagaatt tctgtaattg 2850

 ccaacccact ttgtagaaga ggcatgagcc cttgaatttc aggcaccttt 2900

 tatctaatga gagtttttac agctcatcat tcaaataacg cacaaaaaac 2950

 aaaagccgct atgaccggcg ttgcctctca ctttgaaaga aagactccgt 3000

 aatcttaaac agatgcaaat ccaattaggc ggccaagtag gtggagacga 3050

 agcaccttcc tttccccatc tctgtctgtg tagactccac ttacatcttg 3100

 tggttattct gggttgtgga aggaaaatgt gaatgaaagt agtgctggat 3150

 gcaattactc ctgaacccca cctaggattt aacatccctc attgagccac 3200

 tgggaagcta tggttgagta actaaaggtc tggcaagacc ctgggcacac 3250

 agggagctgc ctagcatctg gcctggagtg tactagccac attcccaagg 3300

 tcccaaggag aaggaagagc tgaaattcat ctcctagtga cagtgccccg 3350

 gccctgtcaa gaatcacata ctcagcattt tgacagttaa tgtcttctct 3400

 ttatttgtgt agtttttagg tggttttata taacatttta attacttgtg 3450

 atttagatgt atccatcctt tttctattaa gaatacaaat gctgggctgg 3500

 gcacagtggc tcacgcctgt aatcccaaca ccttgggagg ccaaggcagg 3550

 cagatcacga catcaggaga tcgagaccat cctggctaac acggtgaaac 3600

 cccgtctcta ctaaaaatac aaaaaaaatt agtcggatgt ggtggcaggt 3650

 gcctgtagtc ccagctactc tggaggctga ggcaggagaa tggcgtgaac 3700

 ccaggaggcg gagcttgcag tgagcagaga tcacgccact gcactccagc 3750

 ctggatgaca gagcgagact ccgcctcaaa aaaagaatac aaatgctcca 3800

 acattatttt ttataactct ggattaccga tgctgagatg tgtgcaggaa 3850

 tacttccaaa taaattttta acattgtaag ccagtagatt ctttggctgg 3900

 gtggcaaatt ttgagtcttc ttgcatattt ggctcatggg ttcataaatt 3950

 gaggccagag actcattgta tatccttgat caattttcta attaaaggaa 4000

 atagcttatt gtttagtaaa atggcccttg gttgtgggaa gaaagagaat 4050

 tatttttaac tgaacgtttt tgttgttttt taaataaagt agccatatgt 4100

 aacgggattt taaaaatata tacattttac aacatggact agaaaaggac 4150

 cattagatca ggggttggca aactatggcc cacgaatcaa acctggcctg 4200

 ccacctgttt ttatacaacc tgtgagctaa gaatggttta tatgttttca 4250

 aatgattggg cagaaaatca aaagaagaac aatatttcat gacacctgaa 4300

 aattctatga aattcagatt tcagtgtcca taaacaaaat gttattagag 4350

 catagccaca cccattcatt tatggtattg tctgggactg ctttcttggc 4400

 agagttgaat agttgggaca gggacagtat agcctgcaaa gcctaaaaga 4450

 tttactactt gtctccttaa agaaaaagtt tgccagctcc tgatctagac 4500

 caagagggag atattgacct tacttgcatt tatccggcat tatttcaaca 4550

 cctcctgtga agaaagtact tttctggcat agctaccgtg agttctcagc 4600

 aggaacttcc cagcgatgat aatgtacatg aaattagcca cgtaacaaga 4650

 gtctatttgc cttgaaaaaa caattatcct tgaacttcct ccagctatgc 4700

 agggattctc attaaagagc tgatctgcat ctgtttatcc attttagtag 4750

 cttttaaata tgattttatg tgaagtgcca tttctttatt ctactaaaga 4800

 gagacagcag aaataaagat cagaagcaaa tgtgagcaaa tctgttttac 4850

 tgttaacttc aattatgaac ttgaaattgt gccacatgac tttttcctct 4900

 aaaaactgga tcctagtgtt ttaattacct gtgtgcagct attttaaata 4950

 gcattttact tgaataatat gtatgttgtc attgtttcat gctatacttt 5000

 gtgggataaa acttgggaat gagtgtggta agaaatttat aaagttttgc 5050

 ttttaaaacg tggacataac tcatttttct agtttttgac aattgtgtgt 5100

 tttagtgtct agtctgcaga gagctgtgtg attaataaac gtggaattaa 5150

 cagaatttcc tctccctgta 5170

<210> 934
<211> 548
<212> PRT
<213> Homo sapien

<400> 934
 Met Ala Thr Cys Ile Trp Leu Arg Ser Cys Gly Ala Arg Arg Leu
   1               5                  10                  15

 Gly Ser Thr Phe Pro Gly Cys Arg Leu Arg Pro Arg Ala Gly Gly
                  20                  25                  30

 Leu Val Pro Ala Ser Gly Pro Ala Pro Gly Pro Ala Gln Leu Arg
                  35                  40                  45

 Cys Tyr Ala Gly Arg Leu Ala Gly Leu Ser Ala Ala Leu Leu Arg
                  50                  55                  60

 Thr Asp Ser Phe Val Gly Gly Arg Trp Leu Pro Ala Ala Ala Thr
                  65                  70                  75

 Phe Pro Val Gln Asp Pro Ala Ser Gly Ala Ala Leu Gly Met Val
                  80                  85                  90

 Ala Asp Cys Gly Val Arg Glu Ala Arg Ala Ala Val Arg Ala Ala
                  95                 100                 105

 Tyr Glu Ala Phe Cys Arg Trp Arg Glu Val Ser Ala Lys Glu Arg
                 110                 115                 120

 Ser Ser Leu Leu Arg Lys Trp Tyr Asn Leu Met Ile Gln Asn Lys
                 125                 130                 135

 Asp Asp Leu Ala Arg Ile Ile Thr Ala Glu Ser Gly Lys Pro Leu
                 140                 145                 150

 Lys Glu Ala His Gly Glu Ile Leu Tyr Ser Ala Phe Phe Leu Glu
                 155                 160                 165

 Trp Phe Ser Glu Glu Ala Arg Arg Val Tyr Gly Asp Ile Ile His
                 170                 175                 180

 Thr Pro Ala Lys Asp Arg Arg Ala Leu Val Leu Lys Gln Pro Ile
                 185                 190                 195

 Gly Val Ala Ala Val Ile Thr Pro Trp Asn Phe Pro Ser Ala Met
                 200                 205                 210

 Ile Thr Arg Lys Val Gly Ala Ala Leu Ala Ala Gly Cys Thr Val
                 215                 220                 225

 Val Val Lys Pro Ala Glu Asp Thr Pro Phe Ser Ala Leu Ala Leu
                 230                 235                 240

 Ala Glu Val Asn Gln Gly Phe Leu Leu Asp Leu Asp Pro Leu Leu
                 245                 250                 255

 Leu Ala Ser Gln Ala Gly Ile Pro Ser Gly Val Tyr Asn Val Ile
                 260                 265                 270

 Pro Cys Ser Arg Lys Asn Ala Lys Glu Val Gly Glu Ala Ile Cys
                 275                 280                 285

 Thr Asp Pro Leu Val Ser Lys Ile Ser Phe Thr Gly Ser Thr Thr
                 290                 295                 300

 Thr Gly Lys Ile Leu Leu His His Ala Ala Asn Ser Val Lys Arg
                 305                 310                 315

 Val Ser Met Glu Leu Gly Gly Leu Ala Pro Phe Ile Val Phe Asp
                 320                 325                 330

 Ser Ala Asn Val Asp Gln Ala Val Ala Gly Ala Met Ala Ser Lys
                 335                 340                 345

 Phe Arg Asn Thr Gly Gln Thr Cys Val Cys Ser Asn Gln Phe Leu
                 350                 355                 360

 Val Gln Arg Gly Ile His Asp Ala Phe Val Lys Ala Phe Ala Glu
                 365                 370                 375

 Ala Met Lys Lys Asn Leu Arg Val Gly Asn Gly Phe Glu Glu Gly
                 380                 385                 390

 Thr Thr Gln Gly Pro Leu Ile Asn Glu Lys Ala Val Glu Lys Val
                 395                 400                 405

 Glu Lys Gln Val Asn Asp Ala Val Ser Lys Gly Ala Thr Val Val
                 410                 415                 420

 Thr Gly Gly Lys Arg His Gln Leu Gly Lys Asn Phe Phe Glu Pro
                 425                 430                 435

 Thr Leu Leu Cys Asn Val Thr Gln Asp Met Leu Cys Thr His Glu
                 440                 445                 450

 Glu Thr Phe Gly Pro Leu Ala Pro Val Ile Lys Phe Asp Thr Glu
                 455                 460                 465

 Glu Glu Ala Ile Ala Ile Ala Asn Ala Ala Asp Val Gly Leu Ala
                 470                 475                 480

 Gly Tyr Phe Tyr Ser Gln Asp Pro Ala Gln Ile Trp Arg Val Ala
                 485                 490                 495

 Glu Gln Leu Glu Val Gly Met Val Gly Val Asn Glu Gly Leu Ile
                 500                 505                 510

 Ser Ser Val Glu Cys Pro Phe Gly Gly Val Lys Gln Ser Gly Leu
                 515                 520                 525

 Gly Arg Glu Gly Ser Lys Tyr Gly Ile Asp Glu Tyr Leu Glu Leu
                 530                 535                 540

 Lys Tyr Val Cys Tyr Gly Gly Leu
                 545

<210> 935
<211> 3286
<212> DNA
<213> Homo sapien

<400> 935
 tagcagcgaa tatactttac accaaatctc agaagattca gaacttagat 50

 gagtggggcc caggacagga accctggagc cttggaagga ggggagcccc 100

 atctccccag aagagcagtg accccagcag agaggggcct ggtgtatcac 150

 tggaggaaat agcctgccaa ggaatacacg tcttcagaag aaattctgtg 200

 tggcttcaag agactgatca aattgtgaga ggaaaacagc ctacccggtc 250

 ctcttttctt caatacaaaa tgagataata ggggttggaa ggaaaacctt 300

 caagacctat ggaagtcagt tgcagccagc tcatcacata gaggtgcagg 350

 tgaggtgtat tttcatcacg gtggaaaatt ctggctgctt catctccatc 400

 tctagagcca atattggagc ttttcaataa aagctatggc ctcaaccacc 450

 agcaccaaga agatgatgga ggaagccacc tgctccatct gcctgagcct 500

 gatgacgaac ccagtaagca tcaactgtgg acacagctac tgccacttgt 550

 gtataacaga cttctttaaa aacccaagcc aaaagcaact gaggcaggag 600

 acattctgct gtccccagtg tcgggctcca tttcatatgg atagcctccg 650

 acccaacaag cagctgggaa gcctcattga agccctcaaa gagacggatc 700

 aagaaatgtc atgtgaggaa cacggagagc agttccacct gttctgcgaa 750

 gacgaggggc agctcatctg ctggcgctgt gagcgggcac cacagcacaa 800

 agggcacacc acagctcttg ttgaagacgt atgccagggc tacaaggaaa 850

 agctccagaa agctgtgaca aaactgaagc aacttgaaga cagatgtacg 900

 gagcagaagc tgtccacagc aatgcgaata actaaatgga aagagaaggt 950

 acagattcag agacaaaaaa tccggtctga ctttaagaat ctccagtgtt 1000

 tcctacatga ggaagagaag tcttatctct ggaggctgga gaaagaagaa 1050

 caacagactc tgagtagact gagggactat gaggctggtc tggggctgaa 1100

 gagcaatgaa ctcaagagcc acatcctgga actggaggaa aaatgtcagg 1150

 gctcagccca gaaattgctg cagaatgtga atgacacttt gagcaggagt 1200

 tgggctgtga agctggaaac atcagaggct gtctccttgg aacttcatac 1250

 tatgtgcaat gtttccaagc tttacttcga tgtgaagaaa atgttaagga 1300

 gtcatcaagt tagtgtgact ctggatccag atacagctca tcacgaacta 1350

 attctctctg aggatcggag acaagtgact cgtggataca cccaggagaa 1400

 tcaggacaca tcttccagga gatttactgc cttcccctgt gtcttgggtt 1450

 gtgaaggctt cacctcagga agacgttact ttgaagtgga tgttggcgaa 1500

 ggaaccggat gggatttagg agtttgtatg gaaaatgtgc agaggggcac 1550

 tggcatgaag caagagcctc agtctggatt ctggaccctc aggctgtgca 1600

 aaaagaaagg ctatgtagca cttacttctc ccccaacttc ccttcatctg 1650

 catgagcagc ccctgcttgt gggaattttt ctggactatg aggccggagt 1700

 tgtatccttt tataacggga atactggctg ccacatcttt actttcccga 1750

 aggcttcctt ctctgatact ctccggccct atttccaggt ttatcaatat 1800

 tctcctttgt ttctgcctcc cccaggtgac taaggaaaag agcagaagct 1850

 ccttggttta accagcacag agaaaataat ataaatccca taagggcaga 1900

 cgtttggtct gttttcttcg ctgtcatttc cttagtagtt agactagtgc 1950

 tgagatttta gtggatatat aattgattta tgttgaatat atggacttag 2000

 caactaaaaa taccacagat ggttaacctg gactggggca aagcaagata 2050

 atagtgatga tcgtatgttg ctgtctccat ccgtctttaa tgggtcaggg 2100

 ctttgatttc caagggtctt caggtgatga gtaggggtac ccacaagtca 2150

 gaaggtctgc gttctcctag tttgtttgct gccatttgaa ctcatgtagg 2200

 gaatgaaaga aagctgcaat tatccgccaa ctgcatttaa aacaaaacaa 2250

 aacagaaaaa tcaaaataac attgactctt ccaaccactg acatgttgtt 2300

 taataatcta agcggcagtc ctggaggcta ccagacttac tgagttctac 2350

 ctgagaaaca gccaagcaaa gtgtgagaga agggttaaga ctggcttaca 2400

 atgagatgct tcaaatgaaa agggaattat gagtaaaatt gaactttgat 2450

 gggggattca gttctggaaa agaatttggt attttccagt ctgctaggac 2500

 caattacctt gaaatatttt aaaatctcag taaatagtta ttgctgaaat 2550

 ggctgttggc agttcttatt atgattcaga gaagagcaaa tagaccttaa 2600

 cttcattttg aaaaagacca aattaccata cccgagtgag taatgacagg 2650

 actacaacta aaacataaac aacattaatg atgaccataa aaagtcacaa 2700

 aattgctaaa tgttataatt tagagttgac ataaaaattg atggccaggc 2750

 atggtggctc acgcctgtaa tcccagaact atgtgaggct gaggcaggtg 2800

 gatcacttga ggtcaggagt tcaacaccag cctggccaac atggtgaaac 2850

 cctgtctcta ctaaaaatac aaaaattagc cgggcatggt ggtaggggcc 2900

 tgtaacccag ctactcgtga ggccaaggca ggagaattgc ttgagcctgc 2950

 agcagctgca gtaagccaag atcatgctgt gcctcaagga aaaaaaaaat 3000

 taatgtttac tgatatttgt tgaagtccta caacatcacc tctgagaata 3050

 ggagaaatga agcaacagtt gtgtctagat gtcagaggca tggctgggcc 3100

 tccatctctg cctaagggag atataaaaga gttcaaacta ttgcccatgt 3150

 tccccagggt cagaagttct aattatgatg atagaggctg ggttgtaagt 3200

 agtaagtgaa gggtagcaga atatgccatc tttggcataa gaagtatttt 3250

 gagttgaaga caattgagaa aaaaaaaaaa aaaaaa 3286

<210> 936
<211> 465
<212> PRT
<213> Homo sapien

<400> 936
 Met Ala Ser Thr Thr Ser Thr Lys Lys Met Met Glu Glu Ala Thr
   1               5                  10                  15

 Cys Ser Ile Cys Leu Ser Leu Met Thr Asn Pro Val Ser Ile Asn
                  20                  25                  30

 Cys Gly His Ser Tyr Cys His Leu Cys Ile Thr Asp Phe Phe Lys
                  35                  40                  45

 Asn Pro Ser Gln Lys Gln Leu Arg Gln Glu Thr Phe Cys Cys Pro
                  50                  55                  60

 Gln Cys Arg Ala Pro Phe His Met Asp Ser Leu Arg Pro Asn Lys
                  65                  70                  75

 Gln Leu Gly Ser Leu Ile Glu Ala Leu Lys Glu Thr Asp Gln Glu
                  80                  85                  90

 Met Ser Cys Glu Glu His Gly Glu Gln Phe His Leu Phe Cys Glu
                  95                 100                 105

 Asp Glu Gly Gln Leu Ile Cys Trp Arg Cys Glu Arg Ala Pro Gln
                 110                 115                 120

 His Lys Gly His Thr Thr Ala Leu Val Glu Asp Val Cys Gln Gly
                 125                 130                 135

 Tyr Lys Glu Lys Leu Gln Lys Ala Val Thr Lys Leu Lys Gln Leu
                 140                 145                 150

 Glu Asp Arg Cys Thr Glu Gln Lys Leu Ser Thr Ala Met Arg Ile
                 155                 160                 165

 Thr Lys Trp Lys Glu Lys Val Gln Ile Gln Arg Gln Lys Ile Arg
                 170                 175                 180

 Ser Asp Phe Lys Asn Leu Gln Cys Phe Leu His Glu Glu Glu Lys
                 185                 190                 195

 Ser Tyr Leu Trp Arg Leu Glu Lys Glu Glu Gln Gln Thr Leu Ser
                 200                 205                 210

 Arg Leu Arg Asp Tyr Glu Ala Gly Leu Gly Leu Lys Ser Asn Glu
                 215                 220                 225

 Leu Lys Ser His Ile Leu Glu Leu Glu Glu Lys Cys Gln Gly Ser
                 230                 235                 240

 Ala Gln Lys Leu Leu Gln Asn Val Asn Asp Thr Leu Ser Arg Ser
                 245                 250                 255

 Trp Ala Val Lys Leu Glu Thr Ser Glu Ala Val Ser Leu Glu Leu
                 260                 265                 270

 His Thr Met Cys Asn Val Ser Lys Leu Tyr Phe Asp Val Lys Lys
                 275                 280                 285

 Met Leu Arg Ser His Gln Val Ser Val Thr Leu Asp Pro Asp Thr
                 290                 295                 300

 Ala His His Glu Leu Ile Leu Ser Glu Asp Arg Arg Gln Val Thr
                 305                 310                 315

 Arg Gly Tyr Thr Gln Glu Asn Gln Asp Thr Ser Ser Arg Arg Phe
                 320                 325                 330

 Thr Ala Phe Pro Cys Val Leu Gly Cys Glu Gly Phe Thr Ser Gly
                 335                 340                 345

 Arg Arg Tyr Phe Glu Val Asp Val Gly Glu Gly Thr Gly Trp Asp
                 350                 355                 360

 Leu Gly Val Cys Met Glu Asn Val Gln Arg Gly Thr Gly Met Lys
                 365                 370                 375

 Gln Glu Pro Gln Ser Gly Phe Trp Thr Leu Arg Leu Cys Lys Lys
                 380                 385                 390

 Lys Gly Tyr Val Ala Leu Thr Ser Pro Pro Thr Ser Leu His Leu
                 395                 400                 405

 His Glu Gln Pro Leu Leu Val Gly Ile Phe Leu Asp Tyr Glu Ala
                 410                 415                 420

 Gly Val Val Ser Phe Tyr Asn Gly Asn Thr Gly Cys His Ile Phe
                 425                 430                 435

 Thr Phe Pro Lys Ala Ser Phe Ser Asp Thr Leu Arg Pro Tyr Phe
                 440                 445                 450

 Gln Val Tyr Gln Tyr Ser Pro Leu Phe Leu Pro Pro Pro Gly Asp
                 455                 460                 465

<210> 937
<211> 1750
<212> DNA
<213> Homo sapien

<400> 937
 caccgcgcaa gcgcatcctg gcctttcttc agtccccacg tgcgatcctt 50

 cccggcaact ttttcgagaa aaatgcccaa attcaaggcg gcccgtgggg 100

 tggggggtca ggaaaaacat gcgcccctgg ccgatcagat cctggctggg 150

 aatgcggtgc gggcgggggt ccgggagaag cggcggggtc gcgggacagg 200

 agaagcggag gaagagtatg tggggccccg gctgagccga cggattttgc 250

 agcaagcacg gcagcaacag gaggaactcg aggccgagca tgggactggg 300

 gacaagcccg cggcgccgcg ggaacgcacc acgcggctgg gtccaagaat 350

 gcctcaggat ggatcagatg acgaggacga ggagtggccc accctggaga 400

 aggctgccac aatgacagca gcgggccatc atgcagaggt ggttgtggac 450

 cctgaggatg agcgtgccat agagatgttc atgaacaaga accctcctgc 500

 caggcgcacc ctggctgaca tcatcatgga gaagctgact gagaagcaga 550

 cagaggttga gacagtcatg tcagaggtgt cgggcttccc tatgccccag 600

 ctggaccccc gggtcctaga agtgtacagg ggggtccggg aggtattatc 650

 taagtaccgc agtggaaaac tgcccaaggc atttaagatc atccctgcac 700

 tctccaactg ggagcaaatc ctctacgtca cagagccgga ggcctggact 750

 gcagctgcca tgtaccaggc caccaggatt tttgcctcta acctgaagga 800

 acgcatggcc cagcgcttct acaaccttgt cctgctccct cgagtacgag 850

 atgacgttgc tgaatacaaa cgactcaact tccatctcta catggctctc 900

 aagaaggccc ttttcaaacc tggagcctgg ttcaaaggga tcctgattcc 950

 actgtgcgag tctggcactt gtaccctccg ggaagccatc attgtgggta 1000

 gcatcatcac caagtgctcc atccctgtgt tgcactccag tgcggccatg 1050

 ctgaaaattg ctgagatgga atacagcggt gccaacagca tcttcctgcg 1100

 actgctgctg gataagaagt atgcactgcc ttaccgggtg ctggatgccc 1150

 tagtcttcca cttcctgggg ttccggacag agaagcgtga actgcctgtg 1200

 ctgtggcacc agtgcctcct gactttggtc cagcgctaca aggccgactt 1250

 ggccacagac cagaaagagg ccctcttaga actgctccgg ctgcagcccc 1300

 atccacagct atcgcccgaa atcaggcgtg agcttcagag tgcagtcccc 1350

 cgcgatgtgg aagatgttcc catcaccgtg gagtgaggaa aacagtcagc 1400

 tgtcctggcc aaaggggttt ggaaggacac caagaccccc gttggtgact 1450

 gaagatgaca ctgagcttta atggctgaag acccagatca gggcagtgac 1500

 agatcacagg gacatctgtg gctcccagtc caggacagga aggactgagg 1550

 gtctggctgg ttccctcttc cattctaggc ccttatccct gtttagttct 1600

 gagagccaac ttgagatacc atatgctagc attcccagtc cccagctggg 1650

 gcttggtgtg agtacttttt ctatggctat tgtgtcaggt cactgtggat 1700

 aaaggcaaag acagatattt attgaaaaaa aaaaaaaaaa aaaaaaaaaa 1750

<210> 938
<211> 301
<212> PRT
<213> Homo sapien

<400> 938
 Met Asn Lys Asn Pro Pro Ala Arg Arg Thr Leu Ala Asp Ile Ile
   1               5                  10                  15

 Met Glu Lys Leu Thr Glu Lys Gln Thr Glu Val Glu Thr Val Met
                  20                  25                  30

 Ser Glu Val Ser Gly Phe Pro Met Pro Gln Leu Asp Pro Arg Val
                  35                  40                  45

 Leu Glu Val Tyr Arg Gly Val Arg Glu Val Leu Ser Lys Tyr Arg
                  50                  55                  60

 Ser Gly Lys Leu Pro Lys Ala Phe Lys Ile Ile Pro Ala Leu Ser
                  65                  70                  75

 Asn Trp Glu Gln Ile Leu Tyr Val Thr Glu Pro Glu Ala Trp Thr
                  80                  85                  90

 Ala Ala Ala Met Tyr Gln Ala Thr Arg Ile Phe Ala Ser Asn Leu
                  95                 100                 105

 Lys Glu Arg Met Ala Gln Arg Phe Tyr Asn Leu Val Leu Leu Pro
                 110                 115                 120

 Arg Val Arg Asp Asp Val Ala Glu Tyr Lys Arg Leu Asn Phe His
                 125                 130                 135

 Leu Tyr Met Ala Leu Lys Lys Ala Leu Phe Lys Pro Gly Ala Trp
                 140                 145                 150

 Phe Lys Gly Ile Leu Ile Pro Leu Cys Glu Ser Gly Thr Cys Thr
                 155                 160                 165

 Leu Arg Glu Ala Ile Ile Val Gly Ser Ile Ile Thr Lys Cys Ser
                 170                 175                 180

 Ile Pro Val Leu His Ser Ser Ala Ala Met Leu Lys Ile Ala Glu
                 185                 190                 195

 Met Glu Tyr Ser Gly Ala Asn Ser Ile Phe Leu Arg Leu Leu Leu
                 200                 205                 210

 Asp Lys Lys Tyr Ala Leu Pro Tyr Arg Val Leu Asp Ala Leu Val
                 215                 220                 225

 Phe His Phe Leu Gly Phe Arg Thr Glu Lys Arg Glu Leu Pro Val
                 230                 235                 240

 Leu Trp His Gln Cys Leu Leu Thr Leu Val Gln Arg Tyr Lys Ala
                 245                 250                 255

 Asp Leu Ala Thr Asp Gln Lys Glu Ala Leu Leu Glu Leu Leu Arg
                 260                 265                 270

 Leu Gln Pro His Pro Gln Leu Ser Pro Glu Ile Arg Arg Glu Leu
                 275                 280                 285

 Gln Ser Ala Val Pro Arg Asp Val Glu Asp Val Pro Ile Thr Val
                 290                 295                 300

 Glu


<210> 939
<211> 1259
<212> DNA
<213> Homo sapien

<400> 939
 ccggagctgg gttgctcctg ctcccgtctc caagtcctgg tacctccttc 50

 aagctgggag agggctctag tccctggttc tgaacactct ggggttctcg 100

 ggtgcaggcc gccatgagca aacggaaggc gccgcaggag actctcaacg 150

 ggggaatcac cgacatgctc acagaactcg caaactttga gaagaacgtg 200

 agccaagcta tccacaagta caatgcttac agaaaagcag catctgttat 250

 agcaaaatac ccacacaaaa taaagagtgg agctgaagct aagaaattgc 300

 ctggagtagg aacaaaaatt gctgaaaaga ttgatgagtt tttagcaact 350

 ggaaaattac gtaaactgga aaagattcgg caggatgata cgagttcatc 400

 catcaatttc ctgactcgag ttagtggcat tggtccatct gctgcaagga 450

 agtttgtaga tgaaggaatt aaaacactag aagatctcag aaaaaatgaa 500

 gataaattga accatcatca gcgaattggg ctgaaatatt ttggggactt 550

 tgaaaaaaga attcctcgtg aagagatgtt acaaatgcaa gatattgtac 600

 taaatgaagt taaaaaagtg gattctgaat acattgctac agtctgtggc 650

 agtttcagaa gaggtgcaga gtccagtggt gacatggatg ttctcctgac 700

 ccatcccagc ttcacttcag aatcaaccaa acagccaaaa ctgttacatc 750

 aggttgtgga gcagttacaa aaggttcatt ttatcacaga taccctgtca 800

 aagggtgaga caaagttcat gggtgtttgc cagcttccca gtaaaaatga 850

 tgaaaaagaa tatccacaca gaagaattga tatcaggttg atacccaaag 900

 atcagtatta ctgtggtgtt ctctatttca ctgggagtga tattttcaat 950

 aagaatatga gggctcatgc cctagaaaag ggtttcacaa tcaatgagta 1000

 caccatccgt cccttgggag tcactggagt tgcaggagaa cccctgccag 1050

 tggatagtga aaaagacatc tttgattaca tccagtggaa ataccgggaa 1100

 cccaaggacc ggagcgaatg aggcctgtat cctccctggc agacacaacc 1150

 caataggagt cttaatttat ttcttaacct ttgctatgta agggtctttg 1200

 gtgtttttaa atgattgttt cttcttcatg cttttgcttg caatgtagtc 1250

 aataaaacc 1259

<210> 940
<211> 335
<212> PRT
<213> Homo sapien

<400> 940
 Met Ser Lys Arg Lys Ala Pro Gln Glu Thr Leu Asn Gly Gly Ile
   1               5                  10                  15

 Thr Asp Met Leu Thr Glu Leu Ala Asn Phe Glu Lys Asn Val Ser
                  20                  25                  30

 Gln Ala Ile His Lys Tyr Asn Ala Tyr Arg Lys Ala Ala Ser Val
                  35                  40                  45

 Ile Ala Lys Tyr Pro His Lys Ile Lys Ser Gly Ala Glu Ala Lys
                  50                  55                  60

 Lys Leu Pro Gly Val Gly Thr Lys Ile Ala Glu Lys Ile Asp Glu
                  65                  70                  75

 Phe Leu Ala Thr Gly Lys Leu Arg Lys Leu Glu Lys Ile Arg Gln
                  80                  85                  90

 Asp Asp Thr Ser Ser Ser Ile Asn Phe Leu Thr Arg Val Ser Gly
                  95                 100                 105

 Ile Gly Pro Ser Ala Ala Arg Lys Phe Val Asp Glu Gly Ile Lys
                 110                 115                 120

 Thr Leu Glu Asp Leu Arg Lys Asn Glu Asp Lys Leu Asn His His
                 125                 130                 135

 Gln Arg Ile Gly Leu Lys Tyr Phe Gly Asp Phe Glu Lys Arg Ile
                 140                 145                 150

 Pro Arg Glu Glu Met Leu Gln Met Gln Asp Ile Val Leu Asn Glu
                 155                 160                 165

 Val Lys Lys Val Asp Ser Glu Tyr Ile Ala Thr Val Cys Gly Ser
                 170                 175                 180

 Phe Arg Arg Gly Ala Glu Ser Ser Gly Asp Met Asp Val Leu Leu
                 185                 190                 195

 Thr His Pro Ser Phe Thr Ser Glu Ser Thr Lys Gln Pro Lys Leu
                 200                 205                 210

 Leu His Gln Val Val Glu Gln Leu Gln Lys Val His Phe Ile Thr
                 215                 220                 225

 Asp Thr Leu Ser Lys Gly Glu Thr Lys Phe Met Gly Val Cys Gln
                 230                 235                 240

 Leu Pro Ser Lys Asn Asp Glu Lys Glu Tyr Pro His Arg Arg Ile
                 245                 250                 255

 Asp Ile Arg Leu Ile Pro Lys Asp Gln Tyr Tyr Cys Gly Val Leu
                 260                 265                 270

 Tyr Phe Thr Gly Ser Asp Ile Phe Asn Lys Asn Met Arg Ala His
                 275                 280                 285

 Ala Leu Glu Lys Gly Phe Thr Ile Asn Glu Tyr Thr Ile Arg Pro
                 290                 295                 300

 Leu Gly Val Thr Gly Val Ala Gly Glu Pro Leu Pro Val Asp Ser
                 305                 310                 315

 Glu Lys Asp Ile Phe Asp Tyr Ile Gln Trp Lys Tyr Arg Glu Pro
                 320                 325                 330

 Lys Asp Arg Ser Glu
                 335

<210> 941
<211> 1194
<212> DNA
<213> Homo sapien

<400> 941
 agcctttaag atttccgggg atggaatccg aaatggaaac gcagagcgcc 50

 agggcagagg agggctttac ccaggtcacc cgcaagggtg gccgacgggc 100

 gaagaaacga caggctgaac agctgtccgc agcaggagag ggcggggatg 150

 cgggccgcat ggacacagag gaggccaggc cggcgaagag gcccgtcttc 200

 ccacccctct gtggggacgg gctcctgagt gggaaagaag aaacaaggaa 250

 aattccagtc ccagctaaca gatacacacc attgaaagaa aactggatga 300

 agatatttac tcctattgtg gaacatttgg gacttcagat acgctttaac 350

 ttgaaatcaa ggaatgtaga aatcaggact tgtaaagaaa ccaaggatgt 400

 tagtgctctg acaaaagcag ctgattttgt gaaagctttt attctcggct 450

 ttcaggtgga ggatgcactt gccctcatca ggttggatga cctcttccta 500

 gagtcttttg aaattacaga tgttaaaccc ctaaagggag accatctatc 550

 cagggcaata ggaagaatcg ctggcaaagg aggaaaaacc aaattcacca 600

 tagagaatgt gacacggaca aggatagttt tggctgatgt gaaagttcac 650

 atccttggct ccttccaaaa tatcaagatg gcaagaactg ccatttgcaa 700

 cctaatcttg ggaaatcctc cttccaaggt ttatggcaat attcgagctg 750

 tggctagcag atcagcagat cgattctgat ttcaagtcag agacttttta 800

 tcttgccttt ggactctggt gaaaaatact ttacagtggt cggtcacaag 850

 aaaccatctg aacaatttca gtcatttgaa gcctccgtcc cttcttccat 900

 tctcagccag aagcataaac agaaaagaaa gatttaagag gattcacact 950

 caacaggttt taggataatt taaatatcaa aaattgattg ttatacttac 1000

 acattaggta taatttatca tttatctgaa atcacatgta gcagattgca 1050

 tagtctgtaa tcctctcaga gggaaacttc ttgtttaaac agctctatat 1100

 ggatttatac ttttatattt ataaatttat aacttcatac aaatttataa 1150

 acatttcttt ataaattgta atttaataga ttatctcaga aaaa 1194

<210> 942
<211> 252
<212> PRT
<213> Homo sapien

<400> 942
 Met Glu Ser Glu Met Glu Thr Gln Ser Ala Arg Ala Glu Glu Gly
   1               5                  10                  15

 Phe Thr Gln Val Thr Arg Lys Gly Gly Arg Arg Ala Lys Lys Arg
                  20                  25                  30

 Gln Ala Glu Gln Leu Ser Ala Ala Gly Glu Gly Gly Asp Ala Gly
                  35                  40                  45

 Arg Met Asp Thr Glu Glu Ala Arg Pro Ala Lys Arg Pro Val Phe
                  50                  55                  60

 Pro Pro Leu Cys Gly Asp Gly Leu Leu Ser Gly Lys Glu Glu Thr
                  65                  70                  75

 Arg Lys Ile Pro Val Pro Ala Asn Arg Tyr Thr Pro Leu Lys Glu
                  80                  85                  90

 Asn Trp Met Lys Ile Phe Thr Pro Ile Val Glu His Leu Gly Leu
                  95                 100                 105

 Gln Ile Arg Phe Asn Leu Lys Ser Arg Asn Val Glu Ile Arg Thr
                 110                 115                 120

 Cys Lys Glu Thr Lys Asp Val Ser Ala Leu Thr Lys Ala Ala Asp
                 125                 130                 135

 Phe Val Lys Ala Phe Ile Leu Gly Phe Gln Val Glu Asp Ala Leu
                 140                 145                 150

 Ala Leu Ile Arg Leu Asp Asp Leu Phe Leu Glu Ser Phe Glu Ile
                 155                 160                 165

 Thr Asp Val Lys Pro Leu Lys Gly Asp His Leu Ser Arg Ala Ile
                 170                 175                 180

 Gly Arg Ile Ala Gly Lys Gly Gly Lys Thr Lys Phe Thr Ile Glu
                 185                 190                 195

 Asn Val Thr Arg Thr Arg Ile Val Leu Ala Asp Val Lys Val His
                 200                 205                 210

 Ile Leu Gly Ser Phe Gln Asn Ile Lys Met Ala Arg Thr Ala Ile
                 215                 220                 225

 Cys Asn Leu Ile Leu Gly Asn Pro Pro Ser Lys Val Tyr Gly Asn
                 230                 235                 240

 Ile Arg Ala Val Ala Ser Arg Ser Ala Asp Arg Phe
                 245                 250

<210> 943
<211> 3914
<212> DNA
<213> Homo sapien

<400> 943
 ctgtgaacag gtatctacag tcggtgaggc ctcttatgaa ggaagaagac 50

 ttcaaacgga tgacagcact tgctcaagat tttgctgtcg gtcttggacc 100

 aagattacag tggtatttga agttaaaatc ctggtgggct acaaattacg 150

 tgagcgactg gtgggaggag tacatctacc tccgaggacg agggccgctc 200

 atggtgaaca gcaactatta tgccatggat ctgctgtata tccttccaac 250

 tcacattcag gcagcaagag ccggcaacgc catccatgcc atcctgcttt 300

 acaggcgcaa actggaccgg gaggaaatca aaccaattcg tcttttggga 350

 tccacgattc cactctgctc cgctcagtgg gagcggatgt ttaatacttc 400

 ccggatccca ggagaggaga cagacaccat ccagcacatg agagacagca 450

 agcacatcgt cgtgtaccat cgaggacgct acttcaaggt ctggctctac 500

 catgatgggc ggctgctgaa gccccgggag atggagcagc agatgcagag 550

 gatcctggac aatacctcgg agcctcagcc cggggaggcc aggctggcag 600

 ccctcaccgc aggagacaga gttccctggg ccaggtgtcg tcaggcctat 650

 tttggacgtg ggaaaaataa gcagtctctt gatgctgtgg agaaagcagc 700

 gttcttcgtg acgttagatg aaactgaaga aggatacaga agtgaagacc 750

 cggatacgtc aatggacagc tacgccaaat ctctactaca cggccgatgt 800

 tacgacaggt ggtttgacaa gtcgttcacg tttgttgtct tcaaaaacgg 850

 gaagatgggc ctcaacgctg aacactcctg ggcagatgcg ccgatcgtgg 900

 cccacctttg ggagtacgtc atgtccattg acagcctcca gctgggctat 950

 gcggaggatg ggcactgcaa aggcgacatc agtccgaaca ttccgtaccc 1000

 caccaggctg cagtgggaca tcccggggga atgtcaagag gttatagaga 1050

 cctccctgaa caccgcaaat cttctggcaa acgacgtgga tttccattcc 1100

 ttcccattcg tagcctttgg taaaggaatc atcaagaaat gtcgcacgag 1150

 cccagacgcc tttgtgcagc tggccctcca gctggcgcac tacaaggaca 1200

 tgggcaagtt ttgcctcaca tacgaggcct ccatgacccg gctcttccga 1250

 gaggggagga cggagaccgt gcgcccctgc accactgagt catgcgactt 1300

 cgtgcgggcc atggtggacc cggcccagac ggtggaacag aggctgaagt 1350

 tgttcaagtt ggcgtctgag aagcatcagc atatgtatcg cctcgccatg 1400

 accggctctg ggatcgatcg tcacctcttc tgcctttacg tggtgtctaa 1450

 atatctcgct gtggagtccc ctttccttaa ggaagtttta tctgagcctt 1500

 ggagattatc aacaagccag acccctcagc agcaagtgga gctgtttgac 1550

 ttggagaata acccagagta cgtgtccagc ggagggggct ttggaccggt 1600

 tgctgatgac ggctatggtg tgtcgtacat ccttgtggga gagaacctca 1650

 tcaatttcca catttcttcc aagttctctt gccctgagac ggattctcat 1700

 cgctttggaa ggcacctgaa agaagcaatg actgacatca tcactttgtt 1750

 tggtctcagt tctaattcca aaaagtaatt ccactggagc tgctgggaag 1800

 gaaaacgagc tcttctggtg caaaccaaat gaaaaatagg cattaatcct 1850

 gaccttagct cgggatgaaa cactgctctt aaaaaaactc agttttcctt 1900

 ccagaaaatg tgggtgtttt ttttttccta gaacagtatc tctcccctgt 1950

 gaagcataac cccactactt ccagacttgc cctcccttgg gggacatctg 2000

 ataaagtctc ccctgatgtc tccgcatcgg cttggattta ttaagggatg 2050

 caaatcttgt tgagttaatg aaggaattag tagggttgtg gcttcacaca 2100

 cagtggaatg gaaatggtgt gctttctcag tggcaaccga aggcctagtg 2150

 cttaagggca tttagcatca tccaagcagg gtaaactttt gttttgttaa 2200

 aagaaaaatg tgttattcaa gttggtgtcc ccagttgtag ctaacacatc 2250

 tggaatgcac taaccaaaat gctgtgcttt ggagacctgc ttttgtcacc 2300

 gtgggtaacc gttcccgtct ggtccagtag cctgtgtttg cctctccaca 2350

 tttgaagcaa gcaggatgca aggtcttcag ttttactgac cttgtatgtc 2400

 ttcaagtctt cacaacccag tgccttaaaa atgaaaggcc ctaaatgtaa 2450

 gggagatgga gagaaagatt tattttgtag agtctttggg tggaattgtg 2500

 ggtatactgt tcccttcaca attgactgag tatggataac cgtacataag 2550

 catttgctac accccaccag ccccctcccc ctcagaaaca ccagttcctt 2600

 cccaagggca gctgtgccag actcccctcc cgggactgcc ttcttgtcat 2650

 cataagcaac aaaagaaata acaggcacat gtcataaaag gggagcaagg 2700

 gccgtgatgg tcagataatt cactcaagaa taaaacatga cacgtgcctc 2750

 aggaggatct ctttcccaaa gtgacagcaa ggagggcagg gcatcggcca 2800

 ccaagcgggg actagcaagt gaggaagggg agggcagtcc accgtggtga 2850

 ggagagagtg gctccacgac cccaagggat ggccttctcc tcccacccgg 2900

 tgaggggaaa gactcaccag agggtgatgg agacagtatg ccggctcacc 2950

 ttggtgacca gccaagatgt ctcaagtgac ggtgctaggt gttcacccag 3000

 cctgtccttc agataggagt gccttcacga aagcgtctca tggaccacaa 3050

 agcaattatg cactgagtca tcttcagtat ttaatgcaaa aatgaaacat 3100

 catggaatga aattcccact gtctgtcatg acaagcttag ctgtccattg 3150

 ttttaaattg tgtatttatt tttttgacca cttggttcta gttgggcctg 3200

 actccttcag agtgctgcac cccgatagta caacagcgat ggctgaactg 3250

 ttggagtcga tggaaggtgc ttgccggaga acacgtgcct tttttttttt 3300

 tttttttttt gagatggagt tgcactccag cctgggcgac agagcgagac 3350

 tccgtctaaa aaaaaaagca aaaacaaacc aacaacaaaa gcccctgact 3400

 gtccgtcaag caggcagcgg ggatgtagct ctctctgccc tgggcaagaa 3450

 tagcacttcc cgttaaaagc cagcagccgg cgtcagtccc tatcagagcc 3500

 agtagatcat gcactgttga ccactgagca atctgtgtta cactagagtt 3550

 cacagggcat tttgagtgta gacgtgagtg cttaaacata tttgggtttc 3600

 tctctcaggt tttaaatgtt tcaaatgtaa ttgttgctca tcagtgcagt 3650

 tatcaatgca attttatatt ccttgagggg agaaagaggg gtcttattgt 3700

 acatgtccaa ggggggtgat aagagtatta tctgtttaat ttaattggaa 3750

 caaaccattg tcttaacgca gccatggttt gaatttgtta tcttgggctg 3800

 accggtgcat gtaaatacag tatgctcttt ggatgtaaat cttagaaatg 3850

 cagtgtgaat gtaggttatc attaataaaa cattaacccc agtctactaa 3900

 aaaaaaaaaa aaaa 3914

<210> 944
<211> 4575
<212> DNA
<213> Homo sapien

<400> 944
 gagcgggcga gggagcgcgc gcggccgcca caaagctcgg gcgccgcggg 50

 gctgcatgcg gcgtacctgg cccggcgcgg cgactgctct ccgggctggc 100

 gggggccggc cgcgagcccc gggggccccg aggccgcagc ttgcctgcgc 150

 gctctgagcc ttcgcaactc gcgagcaaag tttggtggag gcaacgccaa 200

 gcctgagtcc tttcttcctc tcgttcccca aatccgaggg cagcccgcgg 250

 gcgtcatgcc cgcgctcctc cgcagcctgg ggtacgcgct gaagcccggg 300

 aggcttggcg ccggcgaaga cccaaggacc actcttctgc gtttggagtt 350

 gctccccaca accccgggct cgtcgctttc tccatcccga cccagccggg 400

 gcgcggggac aacacaggtc gcggaggagc gttgccattc aagtgactgc 450

 agcagcagcg gcagcgcctc ggttcctgag cccaccgcag gctgaaggca 500

 ttgcgcgtag tccatgcccg tagaggaagt gtgcagatgg gattaacgtc 550

 cacatggaga tatggaagag gaccggggat tggtaccgta accatggtca 600

 gctggggtcg tttcatctgc ctggtcgtgg tcaccatggc aaccttgtcc 650

 ctggcccggc cctccttcag tttagttgag gataccacat tagagccaga 700

 agagccacca accaaatacc aaatctctca accagaagtg tacgtggctg 750

 cgccagggga gtcgctagag gtgcgctgcc tgttgaaaga tgccgccgtg 800

 atcagttgga ctaaggatgg ggtgcacttg gggcccaaca ataggacagt 850

 gcttattggg gagtacttgc agataaaggg cgccacgcct agagactccg 900

 gcctctatgc ttgtactgcc agtaggactg tagacagtga aacttggtac 950

 ttcatggtga atgtcacaga tgccatctca tccggagatg atgaggatga 1000

 caccgatggt gcggaagatt ttgtcagtga gaacagtaac aacaagagag 1050

 caccatactg gaccaacaca gaaaagatgg aaaagcggct ccatgctgtg 1100

 cctgcggcca acactgtcaa gtttcgctgc ccagccgggg ggaacccaat 1150

 gccaaccatg cggtggctga aaaacgggaa ggagtttaag caggagcatc 1200

 gcattggagg ctacaaggta cgaaaccagc actggagcct cattatggaa 1250

 agtgtggtcc catctgacaa gggaaattat acctgtgtgg tggagaatga 1300

 atacgggtcc atcaatcaca cgtaccacct ggatgttgtg gagcgatcgc 1350

 ctcaccggcc catcctccaa gccggactgc cggcaaatgc ctccacagtg 1400

 gtcggaggag acgtagagtt tgtctgcaag gtttacagtg atgcccagcc 1450

 ccacatccag tggatcaagc acgtggaaaa gaacggcagt aaatacgggc 1500

 ccgacgggct gccctacctc aaggttctca aggttctcaa ggccgccggt 1550

 gttaacacca cggacaaaga gattgaggtt ctctatattc ggaatgtaac 1600

 ttttgaggac gctggggaat atacgtgctt ggcgggtaat tctattggga 1650

 tatcctttca ctctgcatgg ttgacagttc tgccagcgcc tggaagagaa 1700

 aaggagatta cagcttcccc agactacctg gagatagcca tttactgcat 1750

 aggggtcttc ttaatcgcct gtatggtggt aacagtcatc ctgtgccgaa 1800

 tgaagaacac gaccaagaag ccagacttca gcagccagcc ggctgtgcac 1850

 aagctgacca aacgtatccc cctgcggaga caggtttcgg ctgagtccag 1900

 ctcctccatg aactccaaca ccccgctggt gaggataaca acacgcctct 1950

 cttcaacggc agacaccccc atgctggcag gggtctccga gtatgaactt 2000

 ccagaggacc caaaatggga gtttccaaga gataagctga cactgggcaa 2050

 gcccctggga gaaggttgct ttgggcaagt ggtcatggcg gaagcagtgg 2100

 gaattgacaa agacaagccc aaggaggcgg tcaccgtggc cgtgaagatg 2150

 ttgaaagatg atgccacaga gaaagacctt tctgatctgg tgtcagagat 2200

 ggagatgatg aagatgattg ggaaacacaa gaatatcata aatcttcttg 2250

 gagcctgcac acaggatggg cctctctatg tcatagttga gtatgcctct 2300

 aaaggcaacc tccgagaata cctccgagcc cggaggccac ccgggatgga 2350

 gtactcctat gacattaacc gtgttcctga ggagcagatg accttcaagg 2400

 acttggtgtc atgcacctac cagctggcca gaggcatgga gtacttggct 2450

 tcccaaaaat gtattcatcg agatttagca gccagaaatg ttttggtaac 2500

 agaaaacaat gtgatgaaaa tagcagactt tggactcgcc agagatatca 2550

 acaatataga ctattacaaa aagaccacca atgggcggct tccagtcaag 2600

 tggatggctc cagaagccct gtttgataga gtatacactc atcagagtga 2650

 tgtctggtcc ttcggggtgt taatgtggga gatcttcact ttagggggct 2700

 cgccctaccc agggattccc gtggaggaac tttttaagct gctgaaggaa 2750

 ggacacagaa tggataagcc agccaactgc accaacgaac tgtacatgat 2800

 gatgagggac tgttggcatg cagtgccctc ccagagacca acgttcaagc 2850

 agttggtaga agacttggat cgaattctca ctctcacaac caatgaggaa 2900

 tacttggacc tcagccaacc tctcgaacag tattcaccta gttaccctga 2950

 cacaagaagt tcttgttctt caggagatga ttctgttttt tctccagacc 3000

 ccatgcctta cgaaccatgc cttcctcagt atccacacat aaacggcagt 3050

 gttaaaacat gaatgactgt gtctgcctgt ccccaaacag gacagcactg 3100

 ggaacctagc tacactgagc agggagacca tgcctcccag agcttgttgt 3150

 ctccacttgt atatatggat cagaggagta aataattgga aaagtaatca 3200

 gcatatgtgt aaagatttat acagttgaaa acttgtaatc ttccccagga 3250

 ggagaagaag gtttctggag cagtggactg ccacaagcca ccatgtaacc 3300

 cctctcacct gccgtgcgta ctggctgtgg accagtagga ctcaaggtgg 3350

 acgtgcgttc tgccttcctt gttaattttg taataattgg agaagattta 3400

 tgtcagcaca cacttacaga gcacaaatgc agtatatagg tgctggatgt 3450

 atgtaaatat attcaaatta tgtataaata tatattatat atttacaagg 3500

 agttattttt tgtattgatt ttaaatggat gtcccaatgc acctagaaaa 3550

 ttggtctctc tttttttaat agctatttgc taaatgctgt tcttacacat 3600

 aatttcttaa ttttcaccga gcagaggtgg aaaaatactt ttgctttcag 3650

 ggaaaatggt ataacgttaa tttattaata aattggtaat atacaaaaca 3700

 attaatcatt tatagttttt tttgtaattt aagtggcatt tctatgcagg 3750

 cagcacagca gactagttaa tctattgctt ggacttaact agttatcaga 3800

 tcctttgaaa agagaatatt tacaatatat gactaatttg gggaaaatga 3850

 agttttgatt tatttgtgtt taaatgctgc tgtcagacga ttgttcttag 3900

 acctcctaaa tgccccatat taaaagaact cattcatagg aaggtgtttc 3950

 attttggtgt gcaaccctgt cattacgtca acgcaacgtc taactggact 4000

 tcccaagata aatggtacca gcgtcctctt aaaagatgcc ttaatccatt 4050

 ccttgaggac agaccttagt tgaaatgata gcagaatgtg cttctctctg 4100

 gcagctggcc ttctgcttct gagttgcaca ttaatcagat tagcctgatt 4150

 ctcttcagtg aattttgata atggcttcca gactctttgc gttggagacg 4200

 cctgttagga tcttcaagtc ccatcataga aaattgaaac acagagttgt 4250

 tctgctgata gttttgggga tacgtccatc tttttaaggg attgctttca 4300

 tctaattctg gcaggacctc accaaaagat ccagcctcat acctacatca 4350

 gacaaaatat cgccgttgtt ccttctgtac taaagtattg tgttttgctt 4400

 tggaaacacc cactcacttt gcaatagccg tgcaagatga atgcagatta 4450

 cactgatctt atgtgttaca aaattggaga aagtatttaa taaaacctgt 4500

 taatttttat actgacaata aaaatgtttc tacagatatt aatgttaaca 4550

 agacaaaata aatgtcacgc aactt 4575

<210> 945
<211> 822
<212> PRT
<213> Homo sapien

<400> 945
 Met Val Ser Trp Gly Arg Phe Ile Cys Leu Val Val Val Thr Met
   1               5                  10                  15

 Ala Thr Leu Ser Leu Ala Arg Pro Ser Phe Ser Leu Val Glu Asp
                  20                  25                  30

 Thr Thr Leu Glu Pro Glu Glu Pro Pro Thr Lys Tyr Gln Ile Ser
                  35                  40                  45

 Gln Pro Glu Val Tyr Val Ala Ala Pro Gly Glu Ser Leu Glu Val
                  50                  55                  60

 Arg Cys Leu Leu Lys Asp Ala Ala Val Ile Ser Trp Thr Lys Asp
                  65                  70                  75

 Gly Val His Leu Gly Pro Asn Asn Arg Thr Val Leu Ile Gly Glu
                  80                  85                  90

 Tyr Leu Gln Ile Lys Gly Ala Thr Pro Arg Asp Ser Gly Leu Tyr
                  95                 100                 105

 Ala Cys Thr Ala Ser Arg Thr Val Asp Ser Glu Thr Trp Tyr Phe
                 110                 115                 120

 Met Val Asn Val Thr Asp Ala Ile Ser Ser Gly Asp Asp Glu Asp
                 125                 130                 135

 Asp Thr Asp Gly Ala Glu Asp Phe Val Ser Glu Asn Ser Asn Asn
                 140                 145                 150

 Lys Arg Ala Pro Tyr Trp Thr Asn Thr Glu Lys Met Glu Lys Arg
                 155                 160                 165

 Leu His Ala Val Pro Ala Ala Asn Thr Val Lys Phe Arg Cys Pro
                 170                 175                 180

 Ala Gly Gly Asn Pro Met Pro Thr Met Arg Trp Leu Lys Asn Gly
                 185                 190                 195

 Lys Glu Phe Lys Gln Glu His Arg Ile Gly Gly Tyr Lys Val Arg
                 200                 205                 210

 Asn Gln His Trp Ser Leu Ile Met Glu Ser Val Val Pro Ser Asp
                 215                 220                 225

 Lys Gly Asn Tyr Thr Cys Val Val Glu Asn Glu Tyr Gly Ser Ile
                 230                 235                 240

 Asn His Thr Tyr His Leu Asp Val Val Glu Arg Ser Pro His Arg
                 245                 250                 255

 Pro Ile Leu Gln Ala Gly Leu Pro Ala Asn Ala Ser Thr Val Val
                 260                 265                 270

 Gly Gly Asp Val Glu Phe Val Cys Lys Val Tyr Ser Asp Ala Gln
                 275                 280                 285

 Pro His Ile Gln Trp Ile Lys His Val Glu Lys Asn Gly Ser Lys
                 290                 295                 300

 Tyr Gly Pro Asp Gly Leu Pro Tyr Leu Lys Val Leu Lys Val Leu
                 305                 310                 315

 Lys Ala Ala Gly Val Asn Thr Thr Asp Lys Glu Ile Glu Val Leu
                 320                 325                 330

 Tyr Ile Arg Asn Val Thr Phe Glu Asp Ala Gly Glu Tyr Thr Cys
                 335                 340                 345

 Leu Ala Gly Asn Ser Ile Gly Ile Ser Phe His Ser Ala Trp Leu
                 350                 355                 360

 Thr Val Leu Pro Ala Pro Gly Arg Glu Lys Glu Ile Thr Ala Ser
                 365                 370                 375

 Pro Asp Tyr Leu Glu Ile Ala Ile Tyr Cys Ile Gly Val Phe Leu
                 380                 385                 390

 Ile Ala Cys Met Val Val Thr Val Ile Leu Cys Arg Met Lys Asn
                 395                 400                 405

 Thr Thr Lys Lys Pro Asp Phe Ser Ser Gln Pro Ala Val His Lys
                 410                 415                 420

 Leu Thr Lys Arg Ile Pro Leu Arg Arg Gln Val Ser Ala Glu Ser
                 425                 430                 435

 Ser Ser Ser Met Asn Ser Asn Thr Pro Leu Val Arg Ile Thr Thr
                 440                 445                 450

 Arg Leu Ser Ser Thr Ala Asp Thr Pro Met Leu Ala Gly Val Ser
                 455                 460                 465

 Glu Tyr Glu Leu Pro Glu Asp Pro Lys Trp Glu Phe Pro Arg Asp
                 470                 475                 480

 Lys Leu Thr Leu Gly Lys Pro Leu Gly Glu Gly Cys Phe Gly Gln
                 485                 490                 495

 Val Val Met Ala Glu Ala Val Gly Ile Asp Lys Asp Lys Pro Lys
                 500                 505                 510

 Glu Ala Val Thr Val Ala Val Lys Met Leu Lys Asp Asp Ala Thr
                 515                 520                 525

 Glu Lys Asp Leu Ser Asp Leu Val Ser Glu Met Glu Met Met Lys
                 530                 535                 540

 Met Ile Gly Lys His Lys Asn Ile Ile Asn Leu Leu Gly Ala Cys
                 545                 550                 555

 Thr Gln Asp Gly Pro Leu Tyr Val Ile Val Glu Tyr Ala Ser Lys
                 560                 565                 570

 Gly Asn Leu Arg Glu Tyr Leu Arg Ala Arg Arg Pro Pro Gly Met
                 575                 580                 585

 Glu Tyr Ser Tyr Asp Ile Asn Arg Val Pro Glu Glu Gln Met Thr
                 590                 595                 600

 Phe Lys Asp Leu Val Ser Cys Thr Tyr Gln Leu Ala Arg Gly Met
                 605                 610                 615

 Glu Tyr Leu Ala Ser Gln Lys Cys Ile His Arg Asp Leu Ala Ala
                 620                 625                 630

 Arg Asn Val Leu Val Thr Glu Asn Asn Val Met Lys Ile Ala Asp
                 635                 640                 645

 Phe Gly Leu Ala Arg Asp Ile Asn Asn Ile Asp Tyr Tyr Lys Lys
                 650                 655                 660

 Thr Thr Asn Gly Arg Leu Pro Val Lys Trp Met Ala Pro Glu Ala
                 665                 670                 675

 Leu Phe Asp Arg Val Tyr Thr His Gln Ser Asp Val Trp Ser Phe
                 680                 685                 690

 Gly Val Leu Met Trp Glu Ile Phe Thr Leu Gly Gly Ser Pro Tyr
                 695                 700                 705

 Pro Gly Ile Pro Val Glu Glu Leu Phe Lys Leu Leu Lys Glu Gly
                 710                 715                 720

 His Arg Met Asp Lys Pro Ala Asn Cys Thr Asn Glu Leu Tyr Met
                 725                 730                 735

 Met Met Arg Asp Cys Trp His Ala Val Pro Ser Gln Arg Pro Thr
                 740                 745                 750

 Phe Lys Gln Leu Val Glu Asp Leu Asp Arg Ile Leu Thr Leu Thr
                 755                 760                 765

 Thr Asn Glu Glu Tyr Leu Asp Leu Ser Gln Pro Leu Glu Gln Tyr
                 770                 775                 780

 Ser Pro Ser Tyr Pro Asp Thr Arg Ser Ser Cys Ser Ser Gly Asp
                 785                 790                 795

 Asp Ser Val Phe Ser Pro Asp Pro Met Pro Tyr Glu Pro Cys Leu
                 800                 805                 810

 Pro Gln Tyr Pro His Ile Asn Gly Ser Val Lys Thr
                 815                 820

<210> 946
<211> 1468
<212> DNA
<213> Homo sapien

<400> 946
 gccactccag ccccgcgccc ctcgccgcgg ccctcgggcg tctgcgccgc 50

 agctgccgcc cccgcctctt tggagtctct cgcggcctca aagcgcggcc 100

 tgcgtcgctt ccggcagttc cagaccgcgg gcgatggctg ccgctggggg 150

 cgcccggctg ctgcgcgccg cttctgctgt cctcggcggc ccggccggcc 200

 ggtggctgca ccacgctggg tcccgcgctg gatccagcgg cctgctgagg 250

 aaccgggggc cgggcgggag cgcggaggcg agccggtcgc tgagcgtgtc 300

 ggcgcgggcc cggagcagct cagaagataa aataacagtc cactttataa 350

 accgtgatgg tgaaacatta acaaccaaag gaaaagttgg tgattctctg 400

 ctagatgttg tggttgaaaa taatctagat attgatggct ttggtgcatg 450

 tgagggaacc ctggcttgtt caacctgtca cctcatcttt gaagatcaca 500

 tatatgagaa gttagatgca atcactgatg aggagaatga catgctcgat 550

 ctggcatatg gactaacaga cagatcacgg ttgggctgcc aaatctgttt 600

 gacaaaatct atggacaata tgactgttcg agtgcctgaa acagtggctg 650

 atgccagaca atccattgat gtgggcaaga cctcctgaac tagaacaaat 700

 aggaatattt tcatggaatt ttacctattt ttataattat tatttcttaa 750

 agtgattaaa tgagaacatg gatgagtgga cttcatatta tgactagctt 800

 tactatttta attcaccttg cataactact gaattttgtc attcttgaaa 850

 gtatgcaatt tttattttgg ttatattaca aaaatgtcaa tcaaatatta 900

 aaaaatagtt aatgtgatag aaaaacctta catatttttt tcttatgttt 950

 gtttagcgac tttagcaaaa tgttttcata taatctcatc tgtttaccta 1000

 gaagataggt taaggaaata tattattatt cctgtttgat gtgggtgaag 1050

 gcagagatct aacctggctt gtttagggcc ataccactaa ttagaaaatc 1100

 tgtgctagaa cctgtgtctt attcctataa gctatgtgtt cagactgaaa 1150

 ctggagaaat tatgactatt ttatttatag tagtagttaa atctgaatgt 1200

 gtatggacta aaaatattta attgctgagt aaactgctta acttcaaaga 1250

 tagttattga ccttataaat aaatatttca aaattttgat tcggaagact 1300

 aagtctggag ctagacatta taatgctatc aaagaagttg atctctgttt 1350

 tgactaaact agaggaaaaa tgattggatg agtttattct tttctaagca 1400

 gaatggttta actttgtact caaagaaaaa taatgctgat ttataaatct 1450

 ctgcctataa tagaatgg 1468

<210> 947
<211> 184
<212> PRT
<213> Homo sapien

<400> 947
 Met Ala Ala Ala Gly Gly Ala Arg Leu Leu Arg Ala Ala Ser Ala
   1               5                  10                  15

 Val Leu Gly Gly Pro Ala Gly Arg Trp Leu His His Ala Gly Ser
                  20                  25                  30

 Arg Ala Gly Ser Ser Gly Leu Leu Arg Asn Arg Gly Pro Gly Gly
                  35                  40                  45

 Ser Ala Glu Ala Ser Arg Ser Leu Ser Val Ser Ala Arg Ala Arg
                  50                  55                  60

 Ser Ser Ser Glu Asp Lys Ile Thr Val His Phe Ile Asn Arg Asp
                  65                  70                  75

 Gly Glu Thr Leu Thr Thr Lys Gly Lys Val Gly Asp Ser Leu Leu
                  80                  85                  90

 Asp Val Val Val Glu Asn Asn Leu Asp Ile Asp Gly Phe Gly Ala
                  95                 100                 105

 Cys Glu Gly Thr Leu Ala Cys Ser Thr Cys His Leu Ile Phe Glu
                 110                 115                 120

 Asp His Ile Tyr Glu Lys Leu Asp Ala Ile Thr Asp Glu Glu Asn
                 125                 130                 135

 Asp Met Leu Asp Leu Ala Tyr Gly Leu Thr Asp Arg Ser Arg Leu
                 140                 145                 150

 Gly Cys Gln Ile Cys Leu Thr Lys Ser Met Asp Asn Met Thr Val
                 155                 160                 165

 Arg Val Pro Glu Thr Val Ala Asp Ala Arg Gln Ser Ile Asp Val
                 170                 175                 180

 Gly Lys Thr Ser


<210> 948
<211> 1381
<212> DNA
<213> Homo sapien

<400> 948
 cttctctttt ccctagactg cagccagcgg agcccgcagc cggcccgagc 50

 caggaaccca ggtccggagc ctcaacttca ggatgttgac aacattgctg 100

 ccgatactgc tgctgtctgg ctgggccttt tgtagccaag acgcctcaga 150

 tggcctccaa agacttcata tgctccagat ctcctacttc cgcgacccct 200

 atcacgtgtg gtaccagggc aacgcgtcgc tggggggaca cctaacgcac 250

 gtgctggaag gcccagacac caacaccacg atcattcagc tgcagccctt 300

 gcaggagccc gagagctggg cgcgcacgca gagtggcctg cagtcctacc 350

 tgctccagtt ccacggcctc gtgcgcctgg tgcaccagga gcggaccttg 400

 gcctttcctc tgaccatccg ctgcttcctg ggctgtgagc tgcctcccga 450

 gggctctaga gcccatgtct tcttcgaagt ggctgtgaat gggagctcct 500

 ttgtgagttt ccggccggag agagccttgt ggcaggcaga cacccaggtc 550

 acctccggag tggtcacctt caccctgcag cagctcaatg cctacaaccg 600

 cactcggtat gaactgcggg aattcctgga ggacacctgt gtgcagtatg 650

 tgcagaaaca tatttccgcg gaaaacacga aagggagcca aacaagccgc 700

 tcctacactt cgctggtcct gggcgtcctg gtgggcggtt tcatcattgc 750

 tggtgtggct gtaggcatct tcctgtgcac aggtggacgg cgatgttaat 800

 tactctccag ccccgtcaga aggggctgga ttgatggagg ctggcaaggg 850

 aaagtttcag ctcactgtga agccagactc cccaactgaa acaccagaag 900

 gtttggagtg acagctcctt tcttctccca catctgccca ctgaagattt 950

 gagggagggg agatggagag gagaggtgga caaagtactt ggtttgctaa 1000

 gaacctaaga acgtgtatgc tttgctgaat tagtctgata agtgaatgtt 1050

 tatctatctt tgtggaaaac agataatgga gttggggcag gaagcctatg 1100

 gcccatcctc caaagacaga cagaatcacc tgaggcgttc aaaagatata 1150

 accaaataaa caagtcatcc acaatcaaaa tacaacattc aatacttcca 1200

 ggtgtgtcag acttgggatg ggacgctgat ataatagggt agaaagaagt 1250

 aacacgaaga agtggtggaa atgtaaaatc caagtcatat ggcagtgatc 1300

 aattattaat caattaataa tattaataaa tttcttatat ttaaggcaaa 1350

 aaaaaaataa aaaaaaaaaa aaaaaaaaaa a 1381

<210> 949
<211> 238
<212> PRT
<213> Homo sapien

<400> 949
 Met Leu Thr Thr Leu Leu Pro Ile Leu Leu Leu Ser Gly Trp Ala
   1               5                  10                  15

 Phe Cys Ser Gln Asp Ala Ser Asp Gly Leu Gln Arg Leu His Met
                  20                  25                  30

 Leu Gln Ile Ser Tyr Phe Arg Asp Pro Tyr His Val Trp Tyr Gln
                  35                  40                  45

 Gly Asn Ala Ser Leu Gly Gly His Leu Thr His Val Leu Glu Gly
                  50                  55                  60

 Pro Asp Thr Asn Thr Thr Ile Ile Gln Leu Gln Pro Leu Gln Glu
                  65                  70                  75

 Pro Glu Ser Trp Ala Arg Thr Gln Ser Gly Leu Gln Ser Tyr Leu
                  80                  85                  90

 Leu Gln Phe His Gly Leu Val Arg Leu Val His Gln Glu Arg Thr
                  95                 100                 105

 Leu Ala Phe Pro Leu Thr Ile Arg Cys Phe Leu Gly Cys Glu Leu
                 110                 115                 120

 Pro Pro Glu Gly Ser Arg Ala His Val Phe Phe Glu Val Ala Val
                 125                 130                 135

 Asn Gly Ser Ser Phe Val Ser Phe Arg Pro Glu Arg Ala Leu Trp
                 140                 145                 150

 Gln Ala Asp Thr Gln Val Thr Ser Gly Val Val Thr Phe Thr Leu
                 155                 160                 165

 Gln Gln Leu Asn Ala Tyr Asn Arg Thr Arg Tyr Glu Leu Arg Glu
                 170                 175                 180

 Phe Leu Glu Asp Thr Cys Val Gln Tyr Val Gln Lys His Ile Ser
                 185                 190                 195

 Ala Glu Asn Thr Lys Gly Ser Gln Thr Ser Arg Ser Tyr Thr Ser
                 200                 205                 210

 Leu Val Leu Gly Val Leu Val Gly Gly Phe Ile Ile Ala Gly Val
                 215                 220                 225

 Ala Val Gly Ile Phe Leu Cys Thr Gly Gly Arg Arg Cys
                 230                 235

<210> 950
<211> 1550
<212> DNA
<213> Homo sapien

<400> 950
 tcaacgcctg cctcccctcg agcgtcctca gcgcagccgc cgcccgcgga 50

 gccagcacga acgagcccag caccggccgg atggagcgtc cgcaacccga 100

 cagcatgccc caggatttgt cagaggccct gaaggaggcc accaaggagg 150

 tgcacaccca ggcagagaat gctgagttca tgaggaactt tcagaagggc 200

 caggtgaccc gagacggctt caagctggtg atggcctccc tgtaccacat 250

 ctatgtggcc ctggaggagg agattgagcg caacaaggag agcccagtct 300

 tcgcccctgt ctacttccca gaagagctgc accgcaaggc tgccctggag 350

 caggacctgg ccttctggta cgggccccgc tggcaggagg tcatccccta 400

 cacaccagcc atgcagcgct atgtgaagcg gctccacgag gtggggcgca 450

 cagagcccga gctgctggtg gcccacgcct acacccgcta cctgggtgac 500

 ctgtctgggg gccaggtgct caaaaagatt gcccagaaag ccctggacct 550

 gcccagctct ggcgagggcc tggccttctt caccttcccc aacattgcca 600

 gtgccaccaa gttcaagcag ctctaccgct cccgcatgaa ctccctggag 650

 atgactcccg cagtcaggca gagggtgata gaagaggcca agactgcgtt 700

 cctgctcaac atccagctct ttgaggagtt gcaggagctg ctgacccatg 750

 acaccaagga ccagagcccc tcacgggcac cagggcttcg ccagcgggcc 800

 agcaacaaag tgcaagattc tgcccccgtg gagactccca gagggaagcc 850

 cccactcaac acccgctccc aggctccgct tctccgatgg gtccttacac 900

 tcagctttct ggtggcgaca gttgctgtag ggctttatgc catgtgaatg 950

 caggcatgct ggctcccagg gccatgaact ttgtccggtg gaaggccttc 1000

 tttctagaga gggaattctc ttggctggct tccttaccgt gggcactgaa 1050

 ggctttcagg gcctccagcc ctctcactgt gtccctctct ctggaaagga 1100

 ggaaggagcc tatggcatct tccccaacga aaagcacatc caggcaatgg 1150

 cctaaacttc agagggggcg aaggggtcag ccctgccctt cagcatcctc 1200

 agttcctgca gcagagcctg gaagacaccc taatgtggca gctgtctcaa 1250

 acctccaaaa gccctgagtt tcaagtatcc ttgttgacac ggccatgacc 1300

 actttccccg tgggccatgg caatttttac acaaacctga aaagatgttg 1350

 tgtcttgtgt ttttgtctta tttttgttgg agccactctg ttcctggctc 1400

 agcctcaaat gcagtatttt tgttgtgttc tgttgttttt atagcagggt 1450

 tggggtggtt tttgagccat gcgtgggtgg ggagggaggt gtttaacggc 1500

 actgtggcct tggtctaact tttgtgtgaa ataataaaca acattgtctg 1550

<210> 951
<211> 288
<212> PRT
<213> Homo sapien

<400> 951
 Met Glu Arg Pro Gln Pro Asp Ser Met Pro Gln Asp Leu Ser Glu
   1               5                  10                  15

 Ala Leu Lys Glu Ala Thr Lys Glu Val His Thr Gln Ala Glu Asn
                  20                  25                  30

 Ala Glu Phe Met Arg Asn Phe Gln Lys Gly Gln Val Thr Arg Asp
                  35                  40                  45

 Gly Phe Lys Leu Val Met Ala Ser Leu Tyr His Ile Tyr Val Ala
                  50                  55                  60

 Leu Glu Glu Glu Ile Glu Arg Asn Lys Glu Ser Pro Val Phe Ala
                  65                  70                  75

 Pro Val Tyr Phe Pro Glu Glu Leu His Arg Lys Ala Ala Leu Glu
                  80                  85                  90

 Gln Asp Leu Ala Phe Trp Tyr Gly Pro Arg Trp Gln Glu Val Ile
                  95                 100                 105

 Pro Tyr Thr Pro Ala Met Gln Arg Tyr Val Lys Arg Leu His Glu
                 110                 115                 120

 Val Gly Arg Thr Glu Pro Glu Leu Leu Val Ala His Ala Tyr Thr
                 125                 130                 135

 Arg Tyr Leu Gly Asp Leu Ser Gly Gly Gln Val Leu Lys Lys Ile
                 140                 145                 150

 Ala Gln Lys Ala Leu Asp Leu Pro Ser Ser Gly Glu Gly Leu Ala
                 155                 160                 165

 Phe Phe Thr Phe Pro Asn Ile Ala Ser Ala Thr Lys Phe Lys Gln
                 170                 175                 180

 Leu Tyr Arg Ser Arg Met Asn Ser Leu Glu Met Thr Pro Ala Val
                 185                 190                 195

 Arg Gln Arg Val Ile Glu Glu Ala Lys Thr Ala Phe Leu Leu Asn
                 200                 205                 210

 Ile Gln Leu Phe Glu Glu Leu Gln Glu Leu Leu Thr His Asp Thr
                 215                 220                 225

 Lys Asp Gln Ser Pro Ser Arg Ala Pro Gly Leu Arg Gln Arg Ala
                 230                 235                 240

 Ser Asn Lys Val Gln Asp Ser Ala Pro Val Glu Thr Pro Arg Gly
                 245                 250                 255

 Lys Pro Pro Leu Asn Thr Arg Ser Gln Ala Pro Leu Leu Arg Trp
                 260                 265                 270

 Val Leu Thr Leu Ser Phe Leu Val Ala Thr Val Ala Val Gly Leu
                 275                 280                 285

 Tyr Ala Met


<210> 952
<211> 2379
<212> DNA
<213> Homo sapien

<400> 952
 ggaattccgg tcggcctctc gcccttcagc tacctgtgcg tccctccgtc 50

 ccgtcccgtc ccggggtcac cccggagcct gtccgctatg cggctcctgc 100

 ctctagcccc aggtcggctc cggcggggca gcccccgcca cctgccctcc 150

 tgcagcccag cgctgctact gctggtgctg ggcggctgcc tgggggtctt 200

 cggggtggct gcgggaaccc ggaggcccaa cgtggtgctg ctcctcacgg 250

 acgaccagga cgaagtgctc ggcggcatga caccactaaa gaaaaccaaa 300

 gctctcatcg gagagatggg gatgactttt tccagtgctt atgtgccaag 350

 tgctctctgc tgccccagca gagccagtat cctgacagga aagtacccac 400

 ataatcatca cgttgtgaac aacactctgg aggggaactg cagtagtaag 450

 tcctggcaga agatccaaga accaaatact ttcccagcaa ttctcagatc 500

 aatgtgtggt tatcagacct tttttgcagg gaaatattta aatgagtacg 550

 gagccccaga tgcaggtgga ctagaacacg ttcctctggg ttggagttac 600

 tggtatgcct tggaaaagaa ttctaagtat tataattaca ccctgtctat 650

 caatgggaag gcacggaagc atggtgaaaa ctatagtgtg gactacctga 700

 cagatgtttt ggctaatgtc tccttggact ttctggacta caagtccaac 750

 tttgagccct tcttcatgat gatcgccact ccagcgcctc attcgccttg 800

 gacagctgca cctcagtacc agaaggcttt ccagaatgtc tttgcaccaa 850

 gaaacaagaa cttcaacatc catggaacga acaagcactg gttaattagg 900

 caagccaaga ctccaatgac taattcttca atacagtttt tagataatgc 950

 atttaggaaa aggtggcaaa ctctcctctc agttgatgac cttgtggaga 1000

 aactggtcaa gaggctggag ttcactgggg agctcaacaa cacttacatc 1050

 ttctatacct cagacaatgg ctatcacaca ggacagtttt ccttgccaat 1100

 agacaagaga cagctgtatg agtttgatat caaagttcca ctgttggttc 1150

 gaggacctgg gatcaaacca aatcagacaa gcaagatgct ggttgccaac 1200

 attgacttgg gtcctactat tttggacatt gctggctacg acctaaataa 1250

 gacacagatg gatgggatgt ccttattgcc cattttgaga ggtgccagta 1300

 acttgacctg gcgatcagat gtcctggtgg aataccaagg agaaggccgt 1350

 aacgtcactg acccaacatg cccttccctg agtcctggcg tatctcaatg 1400

 cttcccagac tgtgtatgtg aagatgctta taacaatacc tatgcctgtg 1450

 tgaggacaat gtcagcattg tggaatttgc agtattgcga gtttgatgac 1500

 caggaggtgt ttgtagaagt ctataatctg actgcagacc cagaccagat 1550

 cactaacatt gctaaaacca tagacccaga gcttttagga aagatgaact 1600

 atcggttaat gatgttacag tcctgttctg ggccaacctg tcgcactcca 1650

 ggggtttttg accccggata caggtttgac ccccgtctca tgttcagcaa 1700

 tcgcggcagt gtcaggactc gaagattttc caaacatctt ctgtagcgac 1750

 ctcacacagc ctctgcagat ggatccctgc acgcctcttt ctgatgaagt 1800

 gattgtagta ggtgtctgta gctagtcttc aagaccacac ctggaagagt 1850

 ttctgggctg gctttaagtc ctgtttgaaa aagcaaccca gtcagctgac 1900

 ttcctcgtgc aatgtgttaa actgtgaact ctgcccatgt gtcaggagtg 1950

 gctgtctctg gtctcttcct ttagctgaca aggacactcc tgaggtcttt 2000

 gttctcactg tatttttttt atcctggggc cacagttctt gattattcct 2050

 cttgtggtta aagactgaat ttgtaaaccc attcagataa atggcagtac 2100

 tttaggacac acacaaacac acagatacac cttttgatat gtaagcttga 2150

 cctaaagtca aaggacctgt gtagcatttc agattgagca cttcactatc 2200

 aaaaatacta acatcacatg gcttgaagag taaccatcag agctgaatca 2250

 tccaagtaag aacaagtacc attgttgatt gataagtaga gatacatttt 2300

 ttatgatgtt catcacagtg tggtaaggtt gcaaattcaa aacatgtcac 2350

 ccaagctctg ttcatgtttt tgtgaattc 2379

<210> 953
<211> 552
<212> PRT
<213> Homo sapien

<400> 953
 Met Arg Leu Leu Pro Leu Ala Pro Gly Arg Leu Arg Arg Gly Ser
   1               5                  10                  15

 Pro Arg His Leu Pro Ser Cys Ser Pro Ala Leu Leu Leu Leu Val
                  20                  25                  30

 Leu Gly Gly Cys Leu Gly Val Phe Gly Val Ala Ala Gly Thr Arg
                  35                  40                  45

 Arg Pro Asn Val Val Leu Leu Leu Thr Asp Asp Gln Asp Glu Val
                  50                  55                  60

 Leu Gly Gly Met Thr Pro Leu Lys Lys Thr Lys Ala Leu Ile Gly
                  65                  70                  75

 Glu Met Gly Met Thr Phe Ser Ser Ala Tyr Val Pro Ser Ala Leu
                  80                  85                  90

 Cys Cys Pro Ser Arg Ala Ser Ile Leu Thr Gly Lys Tyr Pro His
                  95                 100                 105

 Asn His His Val Val Asn Asn Thr Leu Glu Gly Asn Cys Ser Ser
                 110                 115                 120

 Lys Ser Trp Gln Lys Ile Gln Glu Pro Asn Thr Phe Pro Ala Ile
                 125                 130                 135

 Leu Arg Ser Met Cys Gly Tyr Gln Thr Phe Phe Ala Gly Lys Tyr
                 140                 145                 150

 Leu Asn Glu Tyr Gly Ala Pro Asp Ala Gly Gly Leu Glu His Val
                 155                 160                 165

 Pro Leu Gly Trp Ser Tyr Trp Tyr Ala Leu Glu Lys Asn Ser Lys
                 170                 175                 180

 Tyr Tyr Asn Tyr Thr Leu Ser Ile Asn Gly Lys Ala Arg Lys His
                 185                 190                 195

 Gly Glu Asn Tyr Ser Val Asp Tyr Leu Thr Asp Val Leu Ala Asn
                 200                 205                 210

 Val Ser Leu Asp Phe Leu Asp Tyr Lys Ser Asn Phe Glu Pro Phe
                 215                 220                 225

 Phe Met Met Ile Ala Thr Pro Ala Pro His Ser Pro Trp Thr Ala
                 230                 235                 240

 Ala Pro Gln Tyr Gln Lys Ala Phe Gln Asn Val Phe Ala Pro Arg
                 245                 250                 255

 Asn Lys Asn Phe Asn Ile His Gly Thr Asn Lys His Trp Leu Ile
                 260                 265                 270

 Arg Gln Ala Lys Thr Pro Met Thr Asn Ser Ser Ile Gln Phe Leu
                 275                 280                 285

 Asp Asn Ala Phe Arg Lys Arg Trp Gln Thr Leu Leu Ser Val Asp
                 290                 295                 300

 Asp Leu Val Glu Lys Leu Val Lys Arg Leu Glu Phe Thr Gly Glu
                 305                 310                 315

 Leu Asn Asn Thr Tyr Ile Phe Tyr Thr Ser Asp Asn Gly Tyr His
                 320                 325                 330

 Thr Gly Gln Phe Ser Leu Pro Ile Asp Lys Arg Gln Leu Tyr Glu
                 335                 340                 345

 Phe Asp Ile Lys Val Pro Leu Leu Val Arg Gly Pro Gly Ile Lys
                 350                 355                 360

 Pro Asn Gln Thr Ser Lys Met Leu Val Ala Asn Ile Asp Leu Gly
                 365                 370                 375

 Pro Thr Ile Leu Asp Ile Ala Gly Tyr Asp Leu Asn Lys Thr Gln
                 380                 385                 390

 Met Asp Gly Met Ser Leu Leu Pro Ile Leu Arg Gly Ala Ser Asn
                 395                 400                 405

 Leu Thr Trp Arg Ser Asp Val Leu Val Glu Tyr Gln Gly Glu Gly
                 410                 415                 420

 Arg Asn Val Thr Asp Pro Thr Cys Pro Ser Leu Ser Pro Gly Val
                 425                 430                 435

 Ser Gln Cys Phe Pro Asp Cys Val Cys Glu Asp Ala Tyr Asn Asn
                 440                 445                 450

 Thr Tyr Ala Cys Val Arg Thr Met Ser Ala Leu Trp Asn Leu Gln
                 455                 460                 465

 Tyr Cys Glu Phe Asp Asp Gln Glu Val Phe Val Glu Val Tyr Asn
                 470                 475                 480

 Leu Thr Ala Asp Pro Asp Gln Ile Thr Asn Ile Ala Lys Thr Ile
                 485                 490                 495

 Asp Pro Glu Leu Leu Gly Lys Met Asn Tyr Arg Leu Met Met Leu
                 500                 505                 510

 Gln Ser Cys Ser Gly Pro Thr Cys Arg Thr Pro Gly Val Phe Asp
                 515                 520                 525

 Pro Gly Tyr Arg Phe Asp Pro Arg Leu Met Phe Ser Asn Arg Gly
                 530                 535                 540

 Ser Val Arg Thr Arg Arg Phe Ser Lys His Leu Leu
                 545                 550

<210> 954
<211> 5057
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3995-3997, 4906, 4923, 4932, 4995, 5028, 5056
<223> Unknown base

<400> 954
 ggctcctgag gcgcacagcg ccgagcgcgg cgccgcgcac ccgcgcgccg 50

 gacgccagtg accgcgatgg tgaactccag tcgcgtgcag cctcagcagc 100

 ccggggacgc caagcggccg cccgcgcccc gcgcgccgga cccgggccgg 150

 ctgatggctg gctgcgcggc cgtgggcgcc agcctcgccg ccccgggcgg 200

 cctctgcgag cagcggggcc tggagatcga gatgcagcgc atccggcagg 250

 cggccgcgcg ggaccccccg gccggagccg cggcctcccc ttctcctccg 300

 ctctcgtcgt gctcccggca ggcgtggagc cgcgataacc ccggcttcga 350

 ggccgaggag gaggaggagg aggtggaagg ggaagaaggc ggaatggtgg 400

 tggagatgga cgtagagtgg cgcccgggca gccggaggtc ggccgcctcc 450

 tcggccgtga gctccgtggg cgcgcggagc cgggggcttg ggggctacca 500

 cggcgcgggc cacccgagcg ggaggcggcg ccggcgagag gaccagggcc 550

 cgccgtgccc cagcccagtc ggcggcgggg acccgctgca tcgccacctc 600

 cccctggaag ggcagccgcc ccgagtggcc tgggcggaga ggctggttcg 650

 cgggctgcga ggtctctggg gaacaagact catggaggaa agcagcacta 700

 accgagagaa ataccttaaa agtgttttac gggaactggt cacatacctc 750

 ctttttctca tagtcttgtg catcttgacc tacggcatga tgagctccaa 800

 tgtgtactac tacacccgga tgatgtcaca gctcttccta gacacccccg 850

 tgtccaaaac ggagaaaact aactttaaaa ctctgtcttc catggaagac 900

 ttctggaagt tcacagaagg ctccttattg gatgggctgt actggaagat 950

 gcagcccagc aaccagactg aagctgacaa ccgaagtttc atcttctatg 1000

 agaacctgct gttaggggtt ccacgaatac ggcaactccg agtcagaaat 1050

 ggatcctgct ctatccccca ggacttgaga gatgaaatta aagagtgcta 1100

 tgatgtctac tctgtcagta gtgaagatag ggctcccttt gggccccgaa 1150

 atggaaccgc ttggatctac acaagtgaaa aagacttgaa tggtagtagc 1200

 cactggggaa tcattgcaac ttatagtgga gctggctatt atctggattt 1250

 gtcaagaaca agagaggaaa cagctgcaca agttgctagc ctcaagaaaa 1300

 atgtctggct ggaccgagga accagggcaa cttttattga cttctcagtg 1350

 tacaacgcca acattaacct gttctgtgtg gtcaggttat tggttgaatt 1400

 cccagcaaca ggtggtgtga ttccatcttg gcaatttcag cctttaaagc 1450

 tgatccgata tgtcacaact tttgatttct tcctggcagc ctgtgagatt 1500

 atcttttgtt tctttatctt ttactatgtg gtggaagaga tattggaaat 1550

 tcgcattcac aaactacact atttcaggag tttctggaat tgtctggatg 1600

 ttgtgatcgt tgtgctgtca gtggtagcta taggaattaa catatacaga 1650

 acatcaaatg tggaggtgct actacagttt ctggaagatc aaaatacttt 1700

 ccccaacttt gagcatctgg catattggca gatacagttc aacaatatag 1750

 ctgctgtcac agtatttttt gtctggatta agctcttcaa attcatcaat 1800

 tttaacagga ccatgagcca gctctcgaca accatgtctc gatgtgccaa 1850

 agacctgttt ggctttgcta ttatgttctt cattattttc ctagcgtatg 1900

 ctcagttggc ataccttgtc tttggcactc aggtcgatga cttcagtact 1950

 ttccaagagt gtatcttcac tcaattccgt atcattttgg gcgatatcaa 2000

 ctttgcagag attgaggaag ctaatcgagt tttgggacca atttatttca 2050

 ctacatttgt gttctttatg ttcttcattc ttttgaatat gtttttggct 2100

 atcatcaatg atacttactc tgaagtgaaa tctgacttgg cacagcagaa 2150

 agctgaaatg gaactctcag atcttatcag aaagggctac cataaagctt 2200

 tggtcaaact aaaactgaaa aaaaataccg tggatgacat ttcagagagt 2250

 ctgcggcaag gaggaggcaa gttaaacttt gacgaacttc gacaagatct 2300

 caaagggaag ggccatactg atgcagagat tgaggcaata ttcacaaagt 2350

 acgaccaaga tggagaccaa gaactgaccg aacatgaaca tcagcagatg 2400

 agagacgact tggagaaaga gagggaggac ctggatttgg atcacagttc 2450

 tttaccacgt cccatgagca gccgaagttt ccctcgaagc ctggatgact 2500

 ctgaggagga tgacgatgaa gatagcggac atagctccag aaggagggga 2550

 agcatttcta gtggcgtttc ttacgaagag tttcaagtcc tggtgagacg 2600

 agtggaccgg atggagcatt ccatcggcag catagtgtcc aagattgacg 2650

 ccgtgatcgt gaagctagag attatggagc gagccaaact gaagaggagg 2700

 gaggtgctgg gaaggctgtt ggatggggtg gccgaggatg aaaggctggg 2750

 tcgtgacagt gaaatccata gggaacagat ggaacggcta gtacgtgaag 2800

 agttggaacg ctgggaatcc gatgatgcag cttcccagat cagtcatggt 2850

 ttaggcacgc cagtgggact aaatggtcaa cctcgcccca gaagctcccg 2900

 cccatcttcc tcccaatcta cagaaggcat ggaaggtgca ggtggaaatg 2950

 ggagttctaa tgtccacgta tgatatgtgt gtttcagtat gtgtgtttct 3000

 aataagtgag gaagtggctg tcctgaattg ctgtaacaag cacactattt 3050

 atatgccctg accaccatag gatgctagtc tttgtgaccg attgctaatc 3100

 ttctgcactt taatttattt tatataaact ttacccatgg ttcaaagatt 3150

 tttttttctt tttctcatat aagaaatcta ggtgtaaata ttgagtacag 3200

 aaaaaaaatc ttcatgatgt gtattgagcg gtacgcccag ttgccaccat 3250

 gactgagtct tctcagttga caatgaagta gccttttaaa gctagaaaac 3300

 tgtcaaaggg cttctgagtt tcatttccag tcacaaaaat cagtattgtt 3350

 atttttttcc aagagtgtga aggaaaatgg ggcaattcct ttccactctg 3400

 gcatagttca tgagcttaat acatagcttt cttttaagaa aggagccttt 3450

 tttttcaact agcttcctgg ggtaaacttt tctaaaagat aaaatgggaa 3500

 ggaactccaa actatgatag aatctgtgtg aatggttaag atgaatgtta 3550

 aatactatgc ttttttgtaa gttgatcgta tctgatgtct gtgggactaa 3600

 ctgtatcact taatttttac cttattttgg ctctaatttg aataagctga 3650

 gtaaaaccac caaagatcag ttataggata aaatggcatc tctaaccata 3700

 acacaggaga attggaagga gccctaagtt gtcactcagt ttaatttctt 3750

 ttaatggtta gtttagccta aagatttatc tgcatattct ttttcccatg 3800

 tggctctact catttgcaac tgaatttaat gttataactc atctagtgag 3850

 accaacttac taaattttta gtatgcactg aaagttttta tccaacaatt 3900

 atgttcattt taagcaaaat tttaagaaag ttttgaaatt cataaagcat 3950

 ttggttttaa actattttaa gaatatagta ctcggtcagg tatgnnncac 4000

 gcctgtaatc ccagcacttt gggaggccga aacaggcgaa tcacttgagc 4050

 ccaggagttc aagaccaaca tgggcaatgt ggcgaaactc catctctaca 4100

 aaaaatgcaa aaataaaaaa tatagtactc aagtattctt gatcctgtgt 4150

 ttcaaaacta gaatttgtaa tgcaaatgga gctcagtcta ataaaaaaga 4200

 ggttttggta ttaaaagttc atacattaga cagtatcagc caaaatttga 4250

 gttagcaaca ctgttttctt tacgagaggg tctcacccaa atttatgggg 4300

 agaaatctat ttctcaaaaa aaaaaaatct tcttttacag aaatgttgag 4350

 taaggtgaca ttttgagcgc taataagcaa aagagcatgc agtgctgttg 4400

 aataaccctc acttggagaa ccaagagaat cctgtcgttt aatgctatat 4450

 tttaatttca caagttgttc atttaactgg tagaatgtca gtccaatctc 4500

 caatgagaac atgagcaaat agacctttcc aggttgaaag tgaaacatac 4550

 tgggtttctg taagtttttc ctcatggctt catctctatc tttactttct 4600

 cttgaatatg ctacacaaag ttctttatta ctacatacta aagtttgcat 4650

 tccagggata ttgactgtac atatttatgt atatgtacca tgttgttaca 4700

 tgtaaacaaa cttcaatttg aagtgcagct attatgtggt atccatgtgt 4750

 atcgaccatg tgccatatat caattatggt cactagaaag tctctttatg 4800

 atacttttta ttgtactgtt tttcatttca cttgcaaaat tttgcagaat 4850

 tcctcctttc tacccataaa ttacatataa tttttcttct ttagtcatgg 4900

 agaacncccc cccatcatct canccctatt anctttccca tgtgtactgg 4950

 tattattaaa aagacattta catacgcaag tttttcactg acaancaaga 5000

 atgttattaa tgtgtaatac tgagcacntt tacttcttaa taaaaacttg 5050

 atatant 5057

<210> 955
<211> 968
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3995-3997, 4906, 4923, 4932, 4995, 5028, 5056
<223> Unknown amino acid

<400> 955
 Met Val Asn Ser Ser Arg Val Gln Pro Gln Gln Pro Gly Asp Ala
   1               5                  10                  15

 Lys Arg Pro Pro Ala Pro Arg Ala Pro Asp Pro Gly Arg Leu Met
                  20                  25                  30

 Ala Gly Cys Ala Ala Val Gly Ala Ser Leu Ala Ala Pro Gly Gly
                  35                  40                  45

 Leu Cys Glu Gln Arg Gly Leu Glu Ile Glu Met Gln Arg Ile Arg
                  50                  55                  60

 Gln Ala Ala Ala Arg Asp Pro Pro Ala Gly Ala Ala Ala Ser Pro
                  65                  70                  75

 Ser Pro Pro Leu Ser Ser Cys Ser Arg Gln Ala Trp Ser Arg Asp
                  80                  85                  90

 Asn Pro Gly Phe Glu Ala Glu Glu Glu Glu Glu Glu Val Glu Gly
                  95                 100                 105

 Glu Glu Gly Gly Met Val Val Glu Met Asp Val Glu Trp Arg Pro
                 110                 115                 120

 Gly Ser Arg Arg Ser Ala Ala Ser Ser Ala Val Ser Ser Val Gly
                 125                 130                 135

 Ala Arg Ser Arg Gly Leu Gly Gly Tyr His Gly Ala Gly His Pro
                 140                 145                 150

 Ser Gly Arg Arg Arg Arg Arg Glu Asp Gln Gly Pro Pro Cys Pro
                 155                 160                 165

 Ser Pro Val Gly Gly Gly Asp Pro Leu His Arg His Leu Pro Leu
                 170                 175                 180

 Glu Gly Gln Pro Pro Arg Val Ala Trp Ala Glu Arg Leu Val Arg
                 185                 190                 195

 Gly Leu Arg Gly Leu Trp Gly Thr Arg Leu Met Glu Glu Ser Ser
                 200                 205                 210

 Thr Asn Arg Glu Lys Tyr Leu Lys Ser Val Leu Arg Glu Leu Val
                 215                 220                 225

 Thr Tyr Leu Leu Phe Leu Ile Val Leu Cys Ile Leu Thr Tyr Gly
                 230                 235                 240

 Met Met Ser Ser Asn Val Tyr Tyr Tyr Thr Arg Met Met Ser Gln
                 245                 250                 255

 Leu Phe Leu Asp Thr Pro Val Ser Lys Thr Glu Lys Thr Asn Phe
                 260                 265                 270

 Lys Thr Leu Ser Ser Met Glu Asp Phe Trp Lys Phe Thr Glu Gly
                 275                 280                 285

 Ser Leu Leu Asp Gly Leu Tyr Trp Lys Met Gln Pro Ser Asn Gln
                 290                 295                 300

 Thr Glu Ala Asp Asn Arg Ser Phe Ile Phe Tyr Glu Asn Leu Leu
                 305                 310                 315

 Leu Gly Val Pro Arg Ile Arg Gln Leu Arg Val Arg Asn Gly Ser
                 320                 325                 330

 Cys Ser Ile Pro Gln Asp Leu Arg Asp Glu Ile Lys Glu Cys Tyr
                 335                 340                 345

 Asp Val Tyr Ser Val Ser Ser Glu Asp Arg Ala Pro Phe Gly Pro
                 350                 355                 360

 Arg Asn Gly Thr Ala Trp Ile Tyr Thr Ser Glu Lys Asp Leu Asn
                 365                 370                 375

 Gly Ser Ser His Trp Gly Ile Ile Ala Thr Tyr Ser Gly Ala Gly
                 380                 385                 390

 Tyr Tyr Leu Asp Leu Ser Arg Thr Arg Glu Glu Thr Ala Ala Gln
                 395                 400                 405

 Val Ala Ser Leu Lys Lys Asn Val Trp Leu Asp Arg Gly Thr Arg
                 410                 415                 420

 Ala Thr Phe Ile Asp Phe Ser Val Tyr Asn Ala Asn Ile Asn Leu
                 425                 430                 435

 Phe Cys Val Val Arg Leu Leu Val Glu Phe Pro Ala Thr Gly Gly
                 440                 445                 450

 Val Ile Pro Ser Trp Gln Phe Gln Pro Leu Lys Leu Ile Arg Tyr
                 455                 460                 465

 Val Thr Thr Phe Asp Phe Phe Leu Ala Ala Cys Glu Ile Ile Phe
                 470                 475                 480

 Cys Phe Phe Ile Phe Tyr Tyr Val Val Glu Glu Ile Leu Glu Ile
                 485                 490                 495

 Arg Ile His Lys Leu His Tyr Phe Arg Ser Phe Trp Asn Cys Leu
                 500                 505                 510

 Asp Val Val Ile Val Val Leu Ser Val Val Ala Ile Gly Ile Asn
                 515                 520                 525

 Ile Tyr Arg Thr Ser Asn Val Glu Val Leu Leu Gln Phe Leu Glu
                 530                 535                 540

 Asp Gln Asn Thr Phe Pro Asn Phe Glu His Leu Ala Tyr Trp Gln
                 545                 550                 555

 Ile Gln Phe Asn Asn Ile Ala Ala Val Thr Val Phe Phe Val Trp
                 560                 565                 570

 Ile Lys Leu Phe Lys Phe Ile Asn Phe Asn Arg Thr Met Ser Gln
                 575                 580                 585

 Leu Ser Thr Thr Met Ser Arg Cys Ala Lys Asp Leu Phe Gly Phe
                 590                 595                 600

 Ala Ile Met Phe Phe Ile Ile Phe Leu Ala Tyr Ala Gln Leu Ala
                 605                 610                 615

 Tyr Leu Val Phe Gly Thr Gln Val Asp Asp Phe Ser Thr Phe Gln
                 620                 625                 630

 Glu Cys Ile Phe Thr Gln Phe Arg Ile Ile Leu Gly Asp Ile Asn
                 635                 640                 645

 Phe Ala Glu Ile Glu Glu Ala Asn Arg Val Leu Gly Pro Ile Tyr
                 650                 655                 660

 Phe Thr Thr Phe Val Phe Phe Met Phe Phe Ile Leu Leu Asn Met
                 665                 670                 675

 Phe Leu Ala Ile Ile Asn Asp Thr Tyr Ser Glu Val Lys Ser Asp
                 680                 685                 690

 Leu Ala Gln Gln Lys Ala Glu Met Glu Leu Ser Asp Leu Ile Arg
                 695                 700                 705

 Lys Gly Tyr His Lys Ala Leu Val Lys Leu Lys Leu Lys Lys Asn
                 710                 715                 720

 Thr Val Asp Asp Ile Ser Glu Ser Leu Arg Gln Gly Gly Gly Lys
                 725                 730                 735

 Leu Asn Phe Asp Glu Leu Arg Gln Asp Leu Lys Gly Lys Gly His
                 740                 745                 750

 Thr Asp Ala Glu Ile Glu Ala Ile Phe Thr Lys Tyr Asp Gln Asp
                 755                 760                 765

 Gly Asp Gln Glu Leu Thr Glu His Glu His Gln Gln Met Arg Asp
                 770                 775                 780

 Asp Leu Glu Lys Glu Arg Glu Asp Leu Asp Leu Asp His Ser Ser
                 785                 790                 795

 Leu Pro Arg Pro Met Ser Ser Arg Ser Phe Pro Arg Ser Leu Asp
                 800                 805                 810

 Asp Ser Glu Glu Asp Asp Asp Glu Asp Ser Gly His Ser Ser Arg
                 815                 820                 825

 Arg Arg Gly Ser Ile Ser Ser Gly Val Ser Tyr Glu Glu Phe Gln
                 830                 835                 840

 Val Leu Val Arg Arg Val Asp Arg Met Glu His Ser Ile Gly Ser
                 845                 850                 855

 Ile Val Ser Lys Ile Asp Ala Val Ile Val Lys Leu Glu Ile Met
                 860                 865                 870

 Glu Arg Ala Lys Leu Lys Arg Arg Glu Val Leu Gly Arg Leu Leu
                 875                 880                 885

 Asp Gly Val Ala Glu Asp Glu Arg Leu Gly Arg Asp Ser Glu Ile
                 890                 895                 900

 His Arg Glu Gln Met Glu Arg Leu Val Arg Glu Glu Leu Glu Arg
                 905                 910                 915

 Trp Glu Ser Asp Asp Ala Ala Ser Gln Ile Ser His Gly Leu Gly
                 920                 925                 930

 Thr Pro Val Gly Leu Asn Gly Gln Pro Arg Pro Arg Ser Ser Arg
                 935                 940                 945

 Pro Ser Ser Ser Gln Ser Thr Glu Gly Met Glu Gly Ala Gly Gly
                 950                 955                 960

 Asn Gly Ser Ser Asn Val His Val
                 965

<210> 956
<211> 4744
<212> DNA
<213> Homo sapien

<400> 956
 aaataataaa gaaattgaaa acaatacatt aatataccat aacactaaaa 50

 agagcaggag cgagagatga gaaagggaat ccagcccgct ctggagcagt 100

 acctggtgac cgccgggggt ggggaggggg cggctgtcgt cgccgccgcc 150

 gctgcagcct ccatggacaa aagggcactg ctagccagcc ccggcttcgc 200

 cgccgccgcc gccgctgccg ccgccccggg cgcgtacatc cagatcctca 250

 ccacgaacac ttccaccacc tcctgttcct cctccctcca aagcggcgcc 300

 gtagccgccg gccccctcct ccccagtgcc cccggcgcgg agcagaccgc 350

 cggcagcctc ctctacacca cgccgcacgg accctccagc agagccgggc 400

 tgctgcagca gccaccagcg ctgggacgcg gcggcagcgg cggcggcggc 450

 ggccctccgg caaagcgaag gctggagcta ggagaaagcg gtcatcagta 500

 cctctcagat ggtttaaaaa cccccaaggg caaaggaaga gctgcactac 550

 gaagtccaga tagtccaaaa actccaaaat ctccctcaga aaaaacgcgg 600

 tatgatacgt ctcttggtct gctcaccaag aagttcattc agctcctgag 650

 ccagtcaccc gatggggtat tggatttgaa caaggcagca gaagtgctaa 700

 aagtgcaaaa gagaaggatt tatgatatca ccaacgttct ggaaggcatc 750

 cacctcatta agaagaagtc taaaaacaac gtccaatgga tgggctgcag 800

 tctgtctgag gatgggggca tgctggccca gtgtcaaggc ctgtcaaaag 850

 aagtgaccga gctcagtcag gaagagaaga aattagatga actgatccaa 900

 agctgcaccc tggacctcaa actgttaacc gaggattcag agaatcaaag 950

 gttagcttat gttacatatc aagatattcg aaaaattagt ggccttaaag 1000

 accaaactgt tatagttgtg aaagcccctc cagaaacaag acttgaagtg 1050

 cctgactcaa tagagagcct acaaatacat ttggcaagta cccaagggcc 1100

 cattgaggtt tacttatgtc cagaagagac tgaaacacac agtccaatga 1150

 aaacaaacaa ccaagaccac aatgggaata tccctaaacc cgcttccaaa 1200

 gacttggctt caaccaactc aggacatagc gattgctcag tttctatggg 1250

 aaacctttct cctctggcct ccccagccaa cctcttacag cagactgagg 1300

 accaaattcc ttccaaccta gaaggaccgt ttgtgaactt actgcctccc 1350

 ctgctgcaag aggactatct cctgagcctc ggggaggagg aaggcatcag 1400

 cgatctcttc gatgcttacg atttggaaaa gctcccactg gtggaagact 1450

 tcatgtgtag ttgattatgc ttcgtgtgaa ctctccttaa aaaccgatat 1500

 ttttttatca tggaccagaa catctgtcat gcagtgttgt cccttcctac 1550

 cttcttcctc caagagagta tcatgaagta aactacaaac ttcagaagaa 1600

 agctgacatt ttaatgaatt ttttaaaaaa ttaataaaca aattgtctaa 1650

 acgcacagtt gcaggctccc ttgggaaagc cctgctttgc tccaggctcc 1700

 aagatctcct ggctaagtca gcaagtgaga aaatgtgcaa tcaggtgtct 1750

 ctcaccccga attgtccttc ctccttcctc cccggattgg cttgctgtgc 1800

 ctgacggatg ggctgtagaa tggggtctgg ccacctggcc tgctgggaaa 1850

 cagcaatctt ccttaatagc atttcaagcc gtgccttctc cgcagaatgc 1900

 atgtctttga ggtctgctaa tatggaatgg aactgcagca aatgcaaact 1950

 tgaagtcatg caaaagtatg aaatggattt cttcagctct tcttaggaat 2000

 atttaaatta ctgtcataat tcagtttaag ctatgaactg tgtgtcccag 2050

 taggaggtca agaaaacctc cacagccttc tggatgaaga acctgttttc 2100

 aaatatactt gttgcagata cagaagacta gtagagttct gccactctaa 2150

 gctgttgtgg attttcctgt ctccatgaac cactcccatt cccccgtccc 2200

 caatgtgttt gtgagtttcc agttgatttg tagcaaatgc ctacttagtt 2250

 ctttgtggat tgttctagac ttttaatttt tttagctgcc atttaagcat 2300

 tcctgtggca cccatcacca tttcaattta attgtttact ttgaagcggt 2350

 ttttgcaaat tcatattact taagcagagg gagagaacct ctactgatca 2400

 gagcatctaa acctgtgtga tctaaggttt atcagcctct gcaaggagct 2450

 ttgtcccatc gtgcttccat tcccaggagg gggagcttgg agcgagtcag 2500

 tcctggggct tgctgacatg ggtggcccat tggaaaggag aaccaggtca 2550

 gatgatgtaa cagccccaag gagcagcagg catgggtccc tccatccttg 2600

 ggcttcccgg gcccctgtga caggggaaag ggctctctta caccgcactc 2650

 agggagacca cttctcagga tggggtcaga tggagagacc tctagggaga 2700

 aagacatccc cattgtgtga gtggcatttc cttaagctgg caggaacagg 2750

 gagcagccct gtgtcggggg ctggaatagt tctggccaga ccccgttccc 2800

 cttcctctat gaaggaataa gttggaccaa gggaagtcgg ggacgtaaaa 2850

 aatgaagcaa aacaatgcca gggtgtctcc cgctttactc ttcaggaatg 2900

 gtgtcccaag ttggaggctt tgtgtcagct gcaaatccta ccagttatgt 2950

 ccaagaatgg ctttccctcg ggcaggtggc agcggccatc tcccactggg 3000

 aatatggcgt agtatctccg gtccattcct tggatgctaa ggactgcggg 3050

 aatgagggag tcagataaag aacaaacctc gaaacgaaca gttaaattga 3100

 aatgctatgt gcctgaccca atggtaggca catagtaggc actcaactca 3150

 tatgtttaat tgaattgaaa atatccctta ggaaaaaaaa aaaacacaca 3200

 aaaaaccaca agagccccag ccagtttact ccaggtagat ttccacaata 3250

 tgcaaagtgg tggtggggtc aagacagatg acaccagcac tttaaactct 3300

 ttgtgtgggt atgcgtgggt gtatgtttgg gaagaaaaac aaaggtgcag 3350

 actatcttcc tttttttctt cttcagcctc catccctggc ctcctcccct 3400

 cacacacact ggacttggta caaaatgtcg gtgtggtcct agatgaagca 3450

 ttggggtggg ggagggagag ggagctttgt gttaagtgcc tactggaaat 3500

 gcactgtggg gttttttcct gtatgggaaa ccatttatgc caagcttttc 3550

 cccatttccc atatttatct catctggtta gctgcctctg cttccagctt 3600

 tgtgtaattc tctttgccag ctgcacaaag ctgatttttt ccaaagtcta 3650

 aagactgagc tcacctggct agattgttgt gtgttttgtt gaattttttc 3700

 ataatgtaat gccgtattta ttgtttttaa aatgaaagga atactaataa 3750

 gtcttaaaag ttccttcatg cataagattt ttttccagtt actgggctta 3800

 actggtgtac attaattaga tgtccatact gtattttgtt tgcattaagt 3850

 aattttcttt ttgacttagt atccggcaca caaagtgggt tagtactaca 3900

 gtatttgcgt tactttaagt actaagtatg caggtttcct ggtaccattg 3950

 agttgctgct attaaagctc acacacgaaa tggctaaaag ttacaagtgt 4000

 gcaaattatg actgcgtgag ccttagaaaa taaaatgtat aaagggcaac 4050

 acatgagctg tcaaacagtg ttaggagtgt gtttatatgt acagagttgt 4100

 gcatagcaat cgttttattt aagttgatat gtagtctact cacattttca 4150

 ttatttagca attttgtaca aaaatagcaa ttaatttgta aacactgcca 4200

 gaatactttc tagctgcttt gtaatttttt aagagtgtta ttttgttttt 4250

 gtttttctgt tctttgttgt ggctcttgtt ttcatttttg ttgtacgtgt 4300

 agatctgtaa ataaaattgc agtatttaaa gcttaagctt tcaggaaaaa 4350

 gaaaataaga attcagtgtg tgcatgacaa ctcgtgtgta tgagaaggag 4400

 ggatatgaag gaagatggct tgcagagtaa gtcgggtggc aattgtcagg 4450

 gtgtgggaat ttcttttcct acggggtacg tgattttgta aaaaggaagt 4500

 atttctccca aaattgggag taggcaaact actaatcagt ttagctttgt 4550

 gttgtatgct agtttaaaaa agaaaatatg taatataatg taaaaaaaaa 4600

 caaaaaaaag cttttatgat ggattttgta aatagatttg ttacagggtg 4650

 acctgttctc tagctgtgat cttaccactt caaatgggtg taatttgaat 4700

 aaattttgta tggtaaagga tcaataaaat gatttttttt aaga 4744

<210> 957
<211> 465
<212> PRT
<213> Homo sapien

<400> 957
 Met Arg Lys Gly Ile Gln Pro Ala Leu Glu Gln Tyr Leu Val Thr
   1               5                  10                  15

 Ala Gly Gly Gly Glu Gly Ala Ala Val Val Ala Ala Ala Ala Ala
                  20                  25                  30

 Ala Ser Met Asp Lys Arg Ala Leu Leu Ala Ser Pro Gly Phe Ala
                  35                  40                  45

 Ala Ala Ala Ala Ala Ala Ala Ala Pro Gly Ala Tyr Ile Gln Ile
                  50                  55                  60

 Leu Thr Thr Asn Thr Ser Thr Thr Ser Cys Ser Ser Ser Leu Gln
                  65                  70                  75

 Ser Gly Ala Val Ala Ala Gly Pro Leu Leu Pro Ser Ala Pro Gly
                  80                  85                  90

 Ala Glu Gln Thr Ala Gly Ser Leu Leu Tyr Thr Thr Pro His Gly
                  95                 100                 105

 Pro Ser Ser Arg Ala Gly Leu Leu Gln Gln Pro Pro Ala Leu Gly
                 110                 115                 120

 Arg Gly Gly Ser Gly Gly Gly Gly Gly Pro Pro Ala Lys Arg Arg
                 125                 130                 135

 Leu Glu Leu Gly Glu Ser Gly His Gln Tyr Leu Ser Asp Gly Leu
                 140                 145                 150

 Lys Thr Pro Lys Gly Lys Gly Arg Ala Ala Leu Arg Ser Pro Asp
                 155                 160                 165

 Ser Pro Lys Thr Pro Lys Ser Pro Ser Glu Lys Thr Arg Tyr Asp
                 170                 175                 180

 Thr Ser Leu Gly Leu Leu Thr Lys Lys Phe Ile Gln Leu Leu Ser
                 185                 190                 195

 Gln Ser Pro Asp Gly Val Leu Asp Leu Asn Lys Ala Ala Glu Val
                 200                 205                 210

 Leu Lys Val Gln Lys Arg Arg Ile Tyr Asp Ile Thr Asn Val Leu
                 215                 220                 225

 Glu Gly Ile His Leu Ile Lys Lys Lys Ser Lys Asn Asn Val Gln
                 230                 235                 240

 Trp Met Gly Cys Ser Leu Ser Glu Asp Gly Gly Met Leu Ala Gln
                 245                 250                 255

 Cys Gln Gly Leu Ser Lys Glu Val Thr Glu Leu Ser Gln Glu Glu
                 260                 265                 270

 Lys Lys Leu Asp Glu Leu Ile Gln Ser Cys Thr Leu Asp Leu Lys
                 275                 280                 285

 Leu Leu Thr Glu Asp Ser Glu Asn Gln Arg Leu Ala Tyr Val Thr
                 290                 295                 300

 Tyr Gln Asp Ile Arg Lys Ile Ser Gly Leu Lys Asp Gln Thr Val
                 305                 310                 315

 Ile Val Val Lys Ala Pro Pro Glu Thr Arg Leu Glu Val Pro Asp
                 320                 325                 330

 Ser Ile Glu Ser Leu Gln Ile His Leu Ala Ser Thr Gln Gly Pro
                 335                 340                 345

 Ile Glu Val Tyr Leu Cys Pro Glu Glu Thr Glu Thr His Ser Pro
                 350                 355                 360

 Met Lys Thr Asn Asn Gln Asp His Asn Gly Asn Ile Pro Lys Pro
                 365                 370                 375

 Ala Ser Lys Asp Leu Ala Ser Thr Asn Ser Gly His Ser Asp Cys
                 380                 385                 390

 Ser Val Ser Met Gly Asn Leu Ser Pro Leu Ala Ser Pro Ala Asn
                 395                 400                 405

 Leu Leu Gln Gln Thr Glu Asp Gln Ile Pro Ser Asn Leu Glu Gly
                 410                 415                 420

 Pro Phe Val Asn Leu Leu Pro Pro Leu Leu Gln Glu Asp Tyr Leu
                 425                 430                 435

 Leu Ser Leu Gly Glu Glu Glu Gly Ile Ser Asp Leu Phe Asp Ala
                 440                 445                 450

 Tyr Asp Leu Glu Lys Leu Pro Leu Val Glu Asp Phe Met Cys Ser
                 455                 460                 465

<210> 958
<211> 4744
<212> DNA
<213> Homo sapien

<400> 958
 aaataataaa gaaattgaaa acaatacatt aatataccat aacactaaaa 50

 agagcaggag cgagagatga gaaagggaat ccagcccgct ctggagcagt 100

 acctggtgac cgccgggggt ggggaggggg cggctgtcgt cgccgccgcc 150

 gctgcagcct ccatggacaa aagggcactg ctagccagcc ccggcttcgc 200

 cgccgccgcc gccgctgccg ccgccccggg cgcgtacatc cagatcctca 250

 ccacgaacac ttccaccacc tcctgttcct cctccctcca aagcggcgcc 300

 gtagccgccg gccccctcct ccccagtgcc cccggcgcgg agcagaccgc 350

 cggcagcctc ctctacacca cgccgcacgg accctccagc agagccgggc 400

 tgctgcagca gccaccagcg ctgggacgcg gcggcagcgg cggcggcggc 450

 ggccctccgg caaagcgaag gctggagcta ggagaaagcg gtcatcagta 500

 cctctcagat ggtttaaaaa cccccaaggg caaaggaaga gctgcactac 550

 gaagtccaga tagtccaaaa actccaaaat ctccctcaga aaaaacgcgg 600

 tatgatacgt ctcttggtct gctcaccaag aagttcattc agctcctgag 650

 ccagtcaccc gatggggtat tggatttgaa caaggcagca gaagtgctaa 700

 aagtgcaaaa gagaaggatt tatgatatca ccaacgttct ggaaggcatc 750

 cacctcatta agaagaagtc taaaaacaac gtccaatgga tgggctgcag 800

 tctgtctgag gatgggggca tgctggccca gtgtcaaggc ctgtcaaaag 850

 aagtgaccga gctcagtcag gaagagaaga aattagatga actgatccaa 900

 agctgcaccc tggacctcaa actgttaacc gaggattcag agaatcaaag 950

 gttagcttat gttacatatc aagatattcg aaaaattagt ggccttaaag 1000

 accaaactgt tatagttgtg aaagcccctc cagaaacaag acttgaagtg 1050

 cctgactcaa tagagagcct acaaatacat ttggcaagta cccaagggcc 1100

 cattgaggtt tacttatgtc cagaagagac tgaaacacac agtccaatga 1150

 aaacaaacaa ccaagaccac aatgggaata tccctaaacc cgcttccaaa 1200

 gacttggctt caaccaactc aggacatagc gattgctcag tttctatggg 1250

 aaacctttct cctctggcct ccccagccaa cctcttacag cagactgagg 1300

 accaaattcc ttccaaccta gaaggaccgt ttgtgaactt actgcctccc 1350

 ctgctgcaag aggactatct cctgagcctc ggggaggagg aaggcatcag 1400

 cgatctcttc gatgcttacg atttggaaaa gctcccactg gtggaagact 1450

 tcatgtgtag ttgattatgc ttcgtgtgaa ctctccttaa aaaccgatat 1500

 ttttttatca tggaccagaa catctgtcat gcagtgttgt cccttcctac 1550

 cttcttcctc caagagagta tcatgaagta aactacaaac ttcagaagaa 1600

 agctgacatt ttaatgaatt ttttaaaaaa ttaataaaca aattgtctaa 1650

 acgcacagtt gcaggctccc ttgggaaagc cctgctttgc tccaggctcc 1700

 aagatctcct ggctaagtca gcaagtgaga aaatgtgcaa tcaggtgtct 1750

 ctcaccccga attgtccttc ctccttcctc cccggattgg cttgctgtgc 1800

 ctgacggatg ggctgtagaa tggggtctgg ccacctggcc tgctgggaaa 1850

 cagcaatctt ccttaatagc atttcaagcc gtgccttctc cgcagaatgc 1900

 atgtctttga ggtctgctaa tatggaatgg aactgcagca aatgcaaact 1950

 tgaagtcatg caaaagtatg aaatggattt cttcagctct tcttaggaat 2000

 atttaaatta ctgtcataat tcagtttaag ctatgaactg tgtgtcccag 2050

 taggaggtca agaaaacctc cacagccttc tggatgaaga acctgttttc 2100

 aaatatactt gttgcagata cagaagacta gtagagttct gccactctaa 2150

 gctgttgtgg attttcctgt ctccatgaac cactcccatt cccccgtccc 2200

 caatgtgttt gtgagtttcc agttgatttg tagcaaatgc ctacttagtt 2250

 ctttgtggat tgttctagac ttttaatttt tttagctgcc atttaagcat 2300

 tcctgtggca cccatcacca tttcaattta attgtttact ttgaagcggt 2350

 ttttgcaaat tcatattact taagcagagg gagagaacct ctactgatca 2400

 gagcatctaa acctgtgtga tctaaggttt atcagcctct gcaaggagct 2450

 ttgtcccatc gtgcttccat tcccaggagg gggagcttgg agcgagtcag 2500

 tcctggggct tgctgacatg ggtggcccat tggaaaggag aaccaggtca 2550

 gatgatgtaa cagccccaag gagcagcagg catgggtccc tccatccttg 2600

 ggcttcccgg gcccctgtga caggggaaag ggctctctta caccgcactc 2650

 agggagacca cttctcagga tggggtcaga tggagagacc tctagggaga 2700

 aagacatccc cattgtgtga gtggcatttc cttaagctgg caggaacagg 2750

 gagcagccct gtgtcggggg ctggaatagt tctggccaga ccccgttccc 2800

 cttcctctat gaaggaataa gttggaccaa gggaagtcgg ggacgtaaaa 2850

 aatgaagcaa aacaatgcca gggtgtctcc cgctttactc ttcaggaatg 2900

 gtgtcccaag ttggaggctt tgtgtcagct gcaaatccta ccagttatgt 2950

 ccaagaatgg ctttccctcg ggcaggtggc agcggccatc tcccactggg 3000

 aatatggcgt agtatctccg gtccattcct tggatgctaa ggactgcggg 3050

 aatgagggag tcagataaag aacaaacctc gaaacgaaca gttaaattga 3100

 aatgctatgt gcctgaccca atggtaggca catagtaggc actcaactca 3150

 tatgtttaat tgaattgaaa atatccctta ggaaaaaaaa aaaacacaca 3200

 aaaaaccaca agagccccag ccagtttact ccaggtagat ttccacaata 3250

 tgcaaagtgg tggtggggtc aagacagatg acaccagcac tttaaactct 3300

 ttgtgtgggt atgcgtgggt gtatgtttgg gaagaaaaac aaaggtgcag 3350

 actatcttcc tttttttctt cttcagcctc catccctggc ctcctcccct 3400

 cacacacact ggacttggta caaaatgtcg gtgtggtcct agatgaagca 3450

 ttggggtggg ggagggagag ggagctttgt gttaagtgcc tactggaaat 3500

 gcactgtggg gttttttcct gtatgggaaa ccatttatgc caagcttttc 3550

 cccatttccc atatttatct catctggtta gctgcctctg cttccagctt 3600

 tgtgtaattc tctttgccag ctgcacaaag ctgatttttt ccaaagtcta 3650

 aagactgagc tcacctggct agattgttgt gtgttttgtt gaattttttc 3700

 ataatgtaat gccgtattta ttgtttttaa aatgaaagga atactaataa 3750

 gtcttaaaag ttccttcatg cataagattt ttttccagtt actgggctta 3800

 actggtgtac attaattaga tgtccatact gtattttgtt tgcattaagt 3850

 aattttcttt ttgacttagt atccggcaca caaagtgggt tagtactaca 3900

 gtatttgcgt tactttaagt actaagtatg caggtttcct ggtaccattg 3950

 agttgctgct attaaagctc acacacgaaa tggctaaaag ttacaagtgt 4000

 gcaaattatg actgcgtgag ccttagaaaa taaaatgtat aaagggcaac 4050

 acatgagctg tcaaacagtg ttaggagtgt gtttatatgt acagagttgt 4100

 gcatagcaat cgttttattt aagttgatat gtagtctact cacattttca 4150

 ttatttagca attttgtaca aaaatagcaa ttaatttgta aacactgcca 4200

 gaatactttc tagctgcttt gtaatttttt aagagtgtta ttttgttttt 4250

 gtttttctgt tctttgttgt ggctcttgtt ttcatttttg ttgtacgtgt 4300

 agatctgtaa ataaaattgc agtatttaaa gcttaagctt tcaggaaaaa 4350

 gaaaataaga attcagtgtg tgcatgacaa ctcgtgtgta tgagaaggag 4400

 ggatatgaag gaagatggct tgcagagtaa gtcgggtggc aattgtcagg 4450

 gtgtgggaat ttcttttcct acggggtacg tgattttgta aaaaggaagt 4500

 atttctccca aaattgggag taggcaaact actaatcagt ttagctttgt 4550

 gttgtatgct agtttaaaaa agaaaatatg taatataatg taaaaaaaaa 4600

 caaaaaaaag cttttatgat ggattttgta aatagatttg ttacagggtg 4650

 acctgttctc tagctgtgat cttaccactt caaatgggtg taatttgaat 4700

 aaattttgta tggtaaagga tcaataaaat gatttttttt aaga 4744

<210> 959
<211> 465
<212> PRT
<213> Homo sapien

<400> 959
 Met Arg Lys Gly Ile Gln Pro Ala Leu Glu Gln Tyr Leu Val Thr
   1               5                  10                  15

 Ala Gly Gly Gly Glu Gly Ala Ala Val Val Ala Ala Ala Ala Ala
                  20                  25                  30

 Ala Ser Met Asp Lys Arg Ala Leu Leu Ala Ser Pro Gly Phe Ala
                  35                  40                  45

 Ala Ala Ala Ala Ala Ala Ala Ala Pro Gly Ala Tyr Ile Gln Ile
                  50                  55                  60

 Leu Thr Thr Asn Thr Ser Thr Thr Ser Cys Ser Ser Ser Leu Gln
                  65                  70                  75

 Ser Gly Ala Val Ala Ala Gly Pro Leu Leu Pro Ser Ala Pro Gly
                  80                  85                  90

 Ala Glu Gln Thr Ala Gly Ser Leu Leu Tyr Thr Thr Pro His Gly
                  95                 100                 105

 Pro Ser Ser Arg Ala Gly Leu Leu Gln Gln Pro Pro Ala Leu Gly
                 110                 115                 120

 Arg Gly Gly Ser Gly Gly Gly Gly Gly Pro Pro Ala Lys Arg Arg
                 125                 130                 135

 Leu Glu Leu Gly Glu Ser Gly His Gln Tyr Leu Ser Asp Gly Leu
                 140                 145                 150

 Lys Thr Pro Lys Gly Lys Gly Arg Ala Ala Leu Arg Ser Pro Asp
                 155                 160                 165

 Ser Pro Lys Thr Pro Lys Ser Pro Ser Glu Lys Thr Arg Tyr Asp
                 170                 175                 180

 Thr Ser Leu Gly Leu Leu Thr Lys Lys Phe Ile Gln Leu Leu Ser
                 185                 190                 195

 Gln Ser Pro Asp Gly Val Leu Asp Leu Asn Lys Ala Ala Glu Val
                 200                 205                 210

 Leu Lys Val Gln Lys Arg Arg Ile Tyr Asp Ile Thr Asn Val Leu
                 215                 220                 225

 Glu Gly Ile His Leu Ile Lys Lys Lys Ser Lys Asn Asn Val Gln
                 230                 235                 240

 Trp Met Gly Cys Ser Leu Ser Glu Asp Gly Gly Met Leu Ala Gln
                 245                 250                 255

 Cys Gln Gly Leu Ser Lys Glu Val Thr Glu Leu Ser Gln Glu Glu
                 260                 265                 270

 Lys Lys Leu Asp Glu Leu Ile Gln Ser Cys Thr Leu Asp Leu Lys
                 275                 280                 285

 Leu Leu Thr Glu Asp Ser Glu Asn Gln Arg Leu Ala Tyr Val Thr
                 290                 295                 300

 Tyr Gln Asp Ile Arg Lys Ile Ser Gly Leu Lys Asp Gln Thr Val
                 305                 310                 315

 Ile Val Val Lys Ala Pro Pro Glu Thr Arg Leu Glu Val Pro Asp
                 320                 325                 330

 Ser Ile Glu Ser Leu Gln Ile His Leu Ala Ser Thr Gln Gly Pro
                 335                 340                 345

 Ile Glu Val Tyr Leu Cys Pro Glu Glu Thr Glu Thr His Ser Pro
                 350                 355                 360

 Met Lys Thr Asn Asn Gln Asp His Asn Gly Asn Ile Pro Lys Pro
                 365                 370                 375

 Ala Ser Lys Asp Leu Ala Ser Thr Asn Ser Gly His Ser Asp Cys
                 380                 385                 390

 Ser Val Ser Met Gly Asn Leu Ser Pro Leu Ala Ser Pro Ala Asn
                 395                 400                 405

 Leu Leu Gln Gln Thr Glu Asp Gln Ile Pro Ser Asn Leu Glu Gly
                 410                 415                 420

 Pro Phe Val Asn Leu Leu Pro Pro Leu Leu Gln Glu Asp Tyr Leu
                 425                 430                 435

 Leu Ser Leu Gly Glu Glu Glu Gly Ile Ser Asp Leu Phe Asp Ala
                 440                 445                 450

 Tyr Asp Leu Glu Lys Leu Pro Leu Val Glu Asp Phe Met Cys Ser
                 455                 460                 465

<210> 960
<211> 4068
<212> DNA
<213> Homo sapien

<400> 960
 gaattcctcc tctcttcacc ccgttagctg ttttcaatgt aatgctgccg 50

 tccttctctt gcactgcctt ctgcgctaac acctccattc ctgtttataa 100

 ccgtgtattt attacttaat gtatataatg taatgttttg taagttatta 150

 atttatatat ctaacattgc ctgccaatgg tggtgttaaa tttgtgtaga 200

 aaactctgcc taagagttac gactttttct tgtaatgttt tgtattgtgt 250

 attatataac ccaaacgtca cttagtagag acatatggcc cccttggcag 300

 agaggacagg ggtgggcttt tgttcaaagg gtctgccctt tccctgcctg 350

 agttgctact tctgcacaac ccctttatga accagttttc acccgaattt 400

 tgactgtttc atttagaaga aaagcaaaat gagaaaaagc tttcctcatt 450

 tctccttgag atggcaaagc actcagaaat gacatcacat accctaaaga 500

 accctgggat gactaaggca gagagagtct gagaaaactc tttggtgctt 550

 ctgcctttag ttttaggaca catttatgca gatgagctta taagagaccg 600

 ttccctccgc cttcttcctc agaggaagtt tcttggtaga tcaccgacac 650

 ctcatccagg cggggggttg gggggaaact tggcaccagc catcccaggc 700

 agagcaccac tgtgatttgt tctcctggtg gagagagctg gaaggaagga 750

 gccagcgtgc aaataatgaa ggagcacggg ggcaccttca gtagcaccgg 800

 aatcagcggt ggtagcggtg actctgctat ggacagcctg cagccgctcc 850

 agcctaacta catgcctgtg tgtttgtttg cagaagaatc ttatcaaaaa 900

 ttagcaatgg aaacgctgga ggaattagac tggtgtttag accagctaga 950

 gaccatacag acctaccggt ctgtcagtga gatggcttct aacaagttca 1000

 aaagaatgct gaaccgggag ctgacacacc tctcagagat gagccgatca 1050

 gggaaccagg tgtctgaata catttcaaat actttcttag acaagcagaa 1100

 tgatgtggag atcccatctc ctacccagaa agacagggag aaaaagaaaa 1150

 agcagcagct catgacccag ataagtggag tgaagaaatt aatgcatagt 1200

 tcaagcctaa acaatacaag catctcacgc tttggagtca acactgaaaa 1250

 tgaagatcac ctggccaagg agctggaaga cctgaacaaa tggggtctta 1300

 acatctttaa tgtggctgga tattctcaca atagacccct aacatgcatc 1350

 atgtatgcta tattccagga aagagacctc ctaaagacat tcagaatctc 1400

 atctgacaca tttataacct acatgatgac tttagaagac cattaccatt 1450

 ctgacgtggc atatcacaac agcctgcacg ctgctgatgt agcccagtcg 1500

 acccatgttc tcctttctac accagcatta gacgctgtct tcacagattt 1550

 ggagatcctg gctgccattt ttgcagctgc catccatgac gttgatcatc 1600

 ctggagtctc caatcagttt ctcatcaaca caaattcaga acttgctttg 1650

 atgtataatg atgaatctgt gttggaaaat catcaccttg ctgtgggttt 1700

 caaactgctg caagaagaac actgtgacat cttcatgaat ctcaccaaga 1750

 agcagcgtca gacactcagg aagatggtta ttgacatggt gttagcaact 1800

 gatatgtcta aacatatgag cctgctggca gacctgaaga caatggtaga 1850

 aacgaagaaa gttacaagtt caggcgttct tctcctagac aactataccg 1900

 atcgcattca ggtccttcgc aacatggtac actgtgcaga cctgagcaac 1950

 cccaccaagt ccttggaatt gtatcggcaa tggacagacc gcatcatgga 2000

 ggaatttttc cagcagggag acaaagagcg ggagagggga atggaaatta 2050

 gcccaatgtg tgataaacac acagcttctg tggaaaaatc ccaggttggt 2100

 ttcatcgact acattgtcca tccattgtgg gagacatggg cagatttggt 2150

 acagcctgat gctcaggaca ttctcgatac cttagaagat aacaggaact 2200

 ggtatcagag catgatacct caaagtccct caccaccact ggacgagcag 2250

 aacagggact gccagggtct gatggagaag tttcagtttg aactgactct 2300

 cgatgaggaa gattctgaag gacctgagaa ggagggagag ggacacagct 2350

 atttcagcag cacaaagacg ctttgtgtga ttgatccaga aaacagagat 2400

 tccctgggag agactgacat agacattgca acagaagaca agtcccccgt 2450

 ggatacataa tccccctctc cctgtggaga tgaacattct atccttgatg 2500

 agcatgccag ctatgtggta gggccagccc accatggggg ccaagacctg 2550

 cacaggacaa gggccacctg gcctttcagt tacttgagtt tggagtcaga 2600

 aagcaagacc aggaagcaaa tagcagctca ggaaatccca cggttgactt 2650

 gccttgatgg caagcttggt ggagagggct gaagctgttg ctgggggccg 2700

 attctgatca agacacatgg cttgaaaatg gaagacacaa aactgagaga 2750

 tcattctgca ctaagtttcg ggaacttatc cccgacagtg actgaactca 2800

 ctgactaata acttcattta tgaatcttct cacttgtccc tttgtctgcc 2850

 aacctgtgtg ccttttttgt aaaacatttt catgtcttta aaatgcctgt 2900

 tgaatacctg gagtttagta tcaacttcta cacagataag ctttcaaagt 2950

 tgacaaactt ttttgactct ttctggaaaa gggaaagaaa atagtcttcc 3000

 ttctttcttg ggcaatatcc ttcactttac tacagttact tttgcaaaca 3050

 gacagaaagg atacacttct aaccacattt tacttccttc ccctgttgtc 3100

 cagtccaact ccacagtcac tcttaaaact tctctctgtt tgcctgcctc 3150

 caacagtact tttaactttt tgctgtaaac agaataaaat tgaacaaatt 3200

 agggggtaga aaggagcagt ggtgtcgttc accgtgagag tctgcataga 3250

 actcagcagt gtgccctgct gtgtcttgga ccctgccccc cacaggagtt 3300

 gctacagtcc ctggccctgc ttcccatcct cctctcttca ccccgttagc 3350

 tgttttcaat gtaatgctgc cgtccttctc ttgcactgcc ttctgcgcta 3400

 acacctccat tcctgtttat aaccgtgtat ttattactta atgtatataa 3450

 tgtaatgttt tgtaagttat taatttatat atctaacatt gcctgccaat 3500

 ggtggtgtta aatttgtgta gaaaactctg cctaagagtt acgacttttt 3550

 cttgtaatgt tttgtattgt gtattatata acccaaacgt cacttagtag 3600

 agacatatgg cccccttggc agagaggaca ggggtgggct tttgttcaaa 3650

 gggtctgccc tttccctgcc tgagttgcta cttctgcaca acccctttat 3700

 gaaccagttt tggaaacaat attctcacat tagatactaa atggtttata 3750

 ctgagtcttt tacttttgta tagcttgata ggggcagggg caatgggatg 3800

 tagtttttac ccaggttcta tccaaatcta tgtgggcatg agttgggtta 3850

 taactggatc ctactatcat tgtggctttg gttcaaaagg aaacactaca 3900

 tttgctcaca gatgattctt ctgattcttc tgaatgctcc cgaactactg 3950

 actttgaaga ggtagcctcc tgcctgccat taagcaggaa tgtcatgttc 4000

 cagttcatta caaaagaaaa caataaaaca atgtgaattt ttataataaa 4050

 aaaaaaaaaa aggaattc 4068

<210> 961
<211> 564
<212> PRT
<213> Homo sapien

<400> 961
 Met Lys Glu His Gly Gly Thr Phe Ser Ser Thr Gly Ile Ser Gly
   1               5                  10                  15

 Gly Ser Gly Asp Ser Ala Met Asp Ser Leu Gln Pro Leu Gln Pro
                  20                  25                  30

 Asn Tyr Met Pro Val Cys Leu Phe Ala Glu Glu Ser Tyr Gln Lys
                  35                  40                  45

 Leu Ala Met Glu Thr Leu Glu Glu Leu Asp Trp Cys Leu Asp Gln
                  50                  55                  60

 Leu Glu Thr Ile Gln Thr Tyr Arg Ser Val Ser Glu Met Ala Ser
                  65                  70                  75

 Asn Lys Phe Lys Arg Met Leu Asn Arg Glu Leu Thr His Leu Ser
                  80                  85                  90

 Glu Met Ser Arg Ser Gly Asn Gln Val Ser Glu Tyr Ile Ser Asn
                  95                 100                 105

 Thr Phe Leu Asp Lys Gln Asn Asp Val Glu Ile Pro Ser Pro Thr
                 110                 115                 120

 Gln Lys Asp Arg Glu Lys Lys Lys Lys Gln Gln Leu Met Thr Gln
                 125                 130                 135

 Ile Ser Gly Val Lys Lys Leu Met His Ser Ser Ser Leu Asn Asn
                 140                 145                 150

 Thr Ser Ile Ser Arg Phe Gly Val Asn Thr Glu Asn Glu Asp His
                 155                 160                 165

 Leu Ala Lys Glu Leu Glu Asp Leu Asn Lys Trp Gly Leu Asn Ile
                 170                 175                 180

 Phe Asn Val Ala Gly Tyr Ser His Asn Arg Pro Leu Thr Cys Ile
                 185                 190                 195

 Met Tyr Ala Ile Phe Gln Glu Arg Asp Leu Leu Lys Thr Phe Arg
                 200                 205                 210

 Ile Ser Ser Asp Thr Phe Ile Thr Tyr Met Met Thr Leu Glu Asp
                 215                 220                 225

 His Tyr His Ser Asp Val Ala Tyr His Asn Ser Leu His Ala Ala
                 230                 235                 240

 Asp Val Ala Gln Ser Thr His Val Leu Leu Ser Thr Pro Ala Leu
                 245                 250                 255

 Asp Ala Val Phe Thr Asp Leu Glu Ile Leu Ala Ala Ile Phe Ala
                 260                 265                 270

 Ala Ala Ile His Asp Val Asp His Pro Gly Val Ser Asn Gln Phe
                 275                 280                 285

 Leu Ile Asn Thr Asn Ser Glu Leu Ala Leu Met Tyr Asn Asp Glu
                 290                 295                 300

 Ser Val Leu Glu Asn His His Leu Ala Val Gly Phe Lys Leu Leu
                 305                 310                 315

 Gln Glu Glu His Cys Asp Ile Phe Met Asn Leu Thr Lys Lys Gln
                 320                 325                 330

 Arg Gln Thr Leu Arg Lys Met Val Ile Asp Met Val Leu Ala Thr
                 335                 340                 345

 Asp Met Ser Lys His Met Ser Leu Leu Ala Asp Leu Lys Thr Met
                 350                 355                 360

 Val Glu Thr Lys Lys Val Thr Ser Ser Gly Val Leu Leu Leu Asp
                 365                 370                 375

 Asn Tyr Thr Asp Arg Ile Gln Val Leu Arg Asn Met Val His Cys
                 380                 385                 390

 Ala Asp Leu Ser Asn Pro Thr Lys Ser Leu Glu Leu Tyr Arg Gln
                 395                 400                 405

 Trp Thr Asp Arg Ile Met Glu Glu Phe Phe Gln Gln Gly Asp Lys
                 410                 415                 420

 Glu Arg Glu Arg Gly Met Glu Ile Ser Pro Met Cys Asp Lys His
                 425                 430                 435

 Thr Ala Ser Val Glu Lys Ser Gln Val Gly Phe Ile Asp Tyr Ile
                 440                 445                 450

 Val His Pro Leu Trp Glu Thr Trp Ala Asp Leu Val Gln Pro Asp
                 455                 460                 465

 Ala Gln Asp Ile Leu Asp Thr Leu Glu Asp Asn Arg Asn Trp Tyr
                 470                 475                 480

 Gln Ser Met Ile Pro Gln Ser Pro Ser Pro Pro Leu Asp Glu Gln
                 485                 490                 495

 Asn Arg Asp Cys Gln Gly Leu Met Glu Lys Phe Gln Phe Glu Leu
                 500                 505                 510

 Thr Leu Asp Glu Glu Asp Ser Glu Gly Pro Glu Lys Glu Gly Glu
                 515                 520                 525

 Gly His Ser Tyr Phe Ser Ser Thr Lys Thr Leu Cys Val Ile Asp
                 530                 535                 540

 Pro Glu Asn Arg Asp Ser Leu Gly Glu Thr Asp Ile Asp Ile Ala
                 545                 550                 555

 Thr Glu Asp Lys Ser Pro Val Asp Thr
                 560

<210> 962
<211> 9517
<212> DNA
<213> Homo sapien

<400> 962
 gttgctgtcg gagagagaaa gccgcacccg agaggaggtg tgggtgttcc 50

 gcttccatcc taacggaacg agctccctct tcgcggacat gggattaccc 100

 agcggctgct aacccctctc ctcgccctgc tcccccaaac cggcgtggct 150

 ccccgggcac caaggagctg actacagagg agcaggattt gcacccctcg 200

 ctgggcttgc tttggcaaca gagtgcctga cccaggtcag gattttcaag 250

 aaagacatgt ctgacaaaat gtctagcttc ctacatattg gagacatttg 300

 ttctctgtac gcggagggat cgacaaatgg atttattagc accttgggcc 350

 tggttgatga tcgttgtgtt gtacagccag aaaccgggga ccttaacaat 400

 ccacctaaga aattcagaga ctgcctcttt aagctatgtc ccatgaaccg 450

 ctactctgcc caaaagcagt tctggaaagc cgctaagcct ggggccaaca 500

 gcaccacaga cgcagtgcta ctcaacaaac tgcaccacgc tgcagacttg 550

 gaaaagaagc agaatgagac agaaaacagg aaattgctgg ggaccgtaat 600

 ccagtatggc aatgtgatcc agctcctgca tttgaaaagt aataaatacc 650

 taacagtgaa taagaggctt cctgctctgt tggagaagaa tgccatgaga 700

 gtcacattgg acgaggctgg aaatgaaggg tcctggtttt atattcagcc 750

 attctacaag ctgcgatcca ttggagacag cgtggtcata ggtgacaagg 800

 tggttctgaa ccccgtcaat gctggtcagc ccctacatgc tagcagccat 850

 caactggtag ataacccagg ctgcaatgag gtcaattccg tcaactgcaa 900

 tacaagctgg aaaatagtcc ttttcatgaa atggagtgat aacaaagacg 950

 acatattaaa ggggggtgac gtggtgaggc tgtttcatgc tgagcaggag 1000

 aagtttctca cctgtgacga acacaggaag aagcagcacg tcttcctgag 1050

 aaccacgggc cggcagtcgg ccacatctgc caccagttca aaagccctgt 1100

 gggaggtgga ggtggtccag catgacccat gtcggggcgg agcagggtat 1150

 tggaacagcc ttttccgttt caagcatctg gccacggggc attacttggc 1200

 agcagaggtg gaccctgatc aggacgcctc tcgaagtagg ttgcggaatg 1250

 cccaagaaaa gatggtatac tccctggtct ctgtgcctga aggcaatgac 1300

 atctcctcca ttttcgagct agatcccacc actctgcgtg gaggtgacag 1350

 ccttgtccca aggaactctt atgttcggct cagacaccta tgtactaata 1400

 cctgggttca cagcacaaat attcctattg acaaggaaga agaaaagccc 1450

 gtgatgctga aaattggcac ctctcctgtg aaggaggata aggaagcatt 1500

 tgccatagtt ccggtttctc ctgctgaagt tcgggacctg gactttgcca 1550

 atgatgccag caaggtgctg ggctccattg ctgggaagct agagaagggc 1600

 accatcaccc agaatgaaag gaggtctgta accaagctgc tagaagattt 1650

 ggtttacttc gtcactggtg gaactaattc tggtcaagat gttctcgaag 1700

 ttgtcttctc caagcccaac agagaacggc agaaactgat gagagaacag 1750

 aatattctca agcagatctt caagttgtta caagccccat tcacagactg 1800

 cggtgatggc ccaatgcttc ggctggaaga gctcggggac cagcggcacg 1850

 ctcctttcag acacatctgc cggctctgct acagggtgct gagacactcg 1900

 cagcaagact acaggaagaa ccaggagtat atagccaagc agtttggctt 1950

 catgcagaag cagattggct atgatgtgtt ggctgaagac actatcactg 2000

 ccctgctcca caataatcgg aaactcctgg aaaaacacat taccgcggca 2050

 gagattgaca catttgtcag cctggtgcga aagaacaggg agcccagatt 2100

 cttagattac ctctccgacc tctgtgtctc catgaacaaa tcaattccag 2150

 tgacccagga actgatatgt aaagctgtgc tgaaccccac caacgctgac 2200

 atcctgattg agaccaaatt ggttctttct cgttttgaat ttgaaggtgt 2250

 ctcttccact ggagagaatg ctctggaggc aggagaagac gaggaagagg 2300

 tgtggctgtt ttggagggac agcaacaaag agattcgcag caagagtgtg 2350

 agggaattgg ctcaggatgc taaagaaggg cagaaggagg accgagacgt 2400

 tctcagctac tacagatatc agctgaacct ctttgcgagg atgtgtctgg 2450

 accgccaata cctggccatc aacgaaatct caggccagct ggatgtcgat 2500

 ctcattctcc gctgcatgtc tgacgagaac ctgccctatg acctcagggc 2550

 gtccttctgc cgcctcatgc ttcacatgca tgtggaccga gatccccagg 2600

 aacaagtcac ccccgtgaaa tatgcccgcc tctggtcgga gattccctcg 2650

 gagatcgcca ttgacgacta tgatagtagt ggagcttcca aagatgaaat 2700

 taaggagaga tttgctcaga ccatggagtt tgtggaggag tatttaagag 2750

 atgtggtttg tcagaggttc cctttctctg ataaagagaa gaataagctt 2800

 acgtttgagg ttgtaaattt agctaggaat ctcatatact ttggtttcta 2850

 caacttctct gaccttctcc gattaactaa gatccttctg gccatattgg 2900

 actgtgtaca tgtgacaaca atcttcccca ttagcaagat ggcgaaagga 2950

 gaagagaata aaggcagtaa cgtgatgaga tctattcatg gcgtgggaga 3000

 gctgatgacc caggtggtgc tccggggagg aggctttttg cccatgactc 3050

 ccatggctgc tgcccctgaa ggcaatgtga agcaggcaga gcctgagaag 3100

 gaggacatca tggtcatgga caccaagctg aagatcattg agatactcca 3150

 gtttattttg aatgtgaggt tggattatag gatctcctgc ctcctgtgta 3200

 tatttaagcg agagtttgat gaaagcaatt cccagacttc agaaacatcc 3250

 tccggaaaca gcagccaaga agggccaagt aatgtaccag gtgctcttga 3300

 ctttgaacac attgaagaac aagcagaagg catctttgga ggaagtgagg 3350

 agaacacccc actggacttg gatgaccacg gcggcagaac ctttctccgt 3400

 gtcctgctcc acttgacgat gcatgactac ccacccctgg tgtcaggggc 3450

 cctgcagctc ctcttccggc acttcagcca gaggcaggag gtgctccagg 3500

 ccttcaaaca ggttcaactg ctggttacca gccaagatgt ggacaactac 3550

 aaacagatca aacaagactt ggatcaactg aggtccatcg tggaaaagtc 3600

 agagctttgg gtgtacaaag ggcagggccc cgatgagact atggatggtg 3650

 catctggaga aaatgaacat aagaaaacgg aggagggaaa taacaagcca 3700

 caaaagcatg aaagcaccag cagctacaac tacagagtgg tcaaagagat 3750

 tttgattcgg cttagcaaac tctgtgttca agagagtgcc tcagtgagaa 3800

 agagcaggaa gcagcaacag cgtctgctcc ggaacatggg cgcgcacgcc 3850

 gtggtgctgg agctgctgca gattccctat gagaaggccg aagataccaa 3900

 gatgcaagag ataatgaggt tggctcatga atttttgcag aatttctgcg 3950

 caggcaacca gcagaatcaa gctttgctac ataaacacat aaacctgttt 4000

 ctcaacccag ggatcctgga ggcagtaacc atgcagcaca tcttcatgaa 4050

 caatttccag ctttgcagtg agatcaacga gagagttgtt cagcacttcg 4100

 ttcactgcat agagactcac ggtcggaatg tccagtatat aaagttctta 4150

 cagacaattg tcaaggcaga agggaaattt attaaaaaat gccaagacat 4200

 ggttatggcc gagctggtca attcgggaga ggatgtcctc gtgttctaca 4250

 acgacagagc ctctttccag actctgatcc agatgatgcg gtcagaacgg 4300

 gatcggatgg atgagaacag ccctctcatg taccacatcc acttggtcga 4350

 gctcctggct gtgtgcacgg agggtaagaa tgtctacaca gagatcaagt 4400

 gcaactccct gctcccgctg gatgacatcg ttcgcgtggt gacccacgag 4450

 gactgcatcc ctgaggttaa aattgcatac attaacttcc tgaatcactg 4500

 ctatgtggat acagaggtgg aaatgaagga gatttatacc agcaatcaca 4550

 tgtggaaatt gtttgagaat ttccttgtag acatctgcag ggcctgtaac 4600

 aacactagtg acaggaaaca tgcagactcg attttggaga agtatgtcac 4650

 cgaaatcgtc atgagtattg ttactacttt cttcagctct cccttctcag 4700

 accagagtac gactttgcag actcgccagc ctgtctttgt gcaactgctg 4750

 caaggcgtgt tcagggttta ccactgcaac tggttaatgc caagccaaaa 4800

 agcctccgtg gagagctgta ttcgggtgct gtctgatgta gccaagagcc 4850

 gggccattgc cattcccgtg gacctggaca gccaagtcaa caacctcttt 4900

 ctcaagtccc acagcattgt gcagaaaaca gccatgaact ggcggctctc 4950

 agcccgcaat gccgcacgca gggactctgt tctggcagct tccagagact 5000

 accggaatat cattgagaga ttgcaggaca tcgtctccgc gctggaggac 5050

 cgtctcaggc ccctggtgca ggcagagtta tctgtgctcg tggatgttct 5100

 ccacagaccc gagctgcttt tcccagagaa cacagacgcc agaaggaaat 5150

 gtgaaagtgg cggtttcatt tgcaagttaa taaagcatac aaaacagctg 5200

 ctagaagaaa atgaagagaa gctctgcatt aaggtcctac agaccctgag 5250

 ggaaatgatg accaaagata gaggctatgg agaaaagggt gaggcgctca 5300

 ggcaagttct ggtcaaccgt tactatggaa acgtcagacc ttcgggacga 5350

 agagagagcc ttaccagctt tggcaatggc ccactgtcag caggaggacc 5400

 cggcaagccc gggggaggag ggggaggttc cggatccagc tctatgagca 5450

 ggggtgagat gagtctggcc gaggttcagt gtcaccttga caaggagggg 5500

 gcttccaatc tagttatcga cctcatcatg aacgcatcca gtgaccgagt 5550

 gttccatgaa agcattctcc tggccattgc ccttctggaa ggaggcaaca 5600

 ccaccatcca gcactccttt ttctgtcgct tgacagaaga taagaagtca 5650

 gagaaattct ttaaggtgtt ttatgaccgg atgaaggtgg cccagcaaga 5700

 aatcaaagca acagtgacag tgaacaccag tgacttggga aataaaaaga 5750

 aagacgatga ggtagacagg gatgccccat cacggaaaaa agctaaagag 5800

 cccacaacac agataacaga agaggtccgg gatcagctcc tggaggcctc 5850

 cgctgccacc aggaaagcct tcaccacttt caggagggag gctgatcccg 5900

 acgaccacta ccagcctgga gagggcaccc aggccactgc cgacaaggcc 5950

 aaggacgacc tggagatgag cgcggtcatc accatcatgc agcccatcct 6000

 ccgcttcctt cagctcctgt gtgaaaacca caaccgagac ctgcagaact 6050

 tcctccgttg ccaaaataac aagaccaact acaatttggt atgtgagacc 6100

 ctgcagtttc tggactgtat ttgtggaagc acaactggag gccttggtct 6150

 tctgggcttg tatataaatg aaaagaacgt agcgcttatc aaccaaaccc 6200

 tggaaagtct gaccgaatac tgtcaaggac cttgccatga gaaccagaac 6250

 tgcatagcca cccatgaatc caatggcatt gacatcatca cagccctgat 6300

 cctcaatgat atcaatcctt tgggaaagaa gaggatggac cttgtgttag 6350

 aactgaagaa caatgcctcg aagttgctcc tggccatcat ggaaagcagg 6400

 cacgacagtg aaaacgcaga gaggatactt tataacatga ggcccaagga 6450

 actggtggaa gtgatcaaga aagcctacat gcaaggtgaa gtggaatttg 6500

 aggatggaga aaacggtgag gatggggcgg cgtcccccag gaacgtgggg 6550

 cacaacatct acatattagc ccatcagttg gctcggcata acaaagaact 6600

 tcagagcatg ctgaaacctg gtggccaagt ggacggagat gaagccctgg 6650

 agttttatgc caagcacacg gcgcagatag agattgtcag attagaccga 6700

 acaatggaac agatagtctt tcccgtgccc agcatatgtg aattcctaac 6750

 caaggagtca aaactacgaa tttactatac tacagagaga gacgaacaag 6800

 gcagcaaaat caatgatttc tttctgcggt ctgaagacct cttcaatgaa 6850

 atgaattggc agaagaaact gagagcccag cccgtgttgt actggtgtgc 6900

 ccgcaacatg tctttctgga gcagcatttc gtttaacctg gccgtcctga 6950

 tgaacctgct ggtggcgttt ttctacccgt ttaagggagt ccgaggagga 7000

 accctggagc cccactggtc gggactcctg tggacagcca tgctcatctc 7050

 tctggccatc gtcattgccc tccccaagcc ccatggcatc cgggccttaa 7100

 ttgcctccac aattctacga ctgatatttt cagtcgggtt acaacccacg 7150

 ttgtttcttc tgggcgcttt caatgtatgc aataaaatca tctttctaat 7200

 gagctttgtg ggcaactgtg ggacattcac aagaggctac cgagccatgg 7250

 ttctggatgt tgagttcctc tatcatttgt tgtatctggt gatctgtgcc 7300

 atggggctct ttgtccatga attcttctac agtctgctgc tttttgattt 7350

 agtgtacaga gaagagactt tgcttaatgt cattaaaagt gtcactcgca 7400

 atggacggtc catcatcctg acagcagttc tggctctgat cctcgtttac 7450

 ctgttctcaa tagtgggcta tcttttcttc aaggatgact ttatcttgga 7500

 agtagatagg ctgcccaatg aaacagctgt tccagaaacc ggcgagagtt 7550

 tggcaagcga gttcctgttc tccgatgtgt gtagggtgga gagtggggag 7600

 aactgctcct ctcctgcacc cagagaagag ctggtccctg cagaagagac 7650

 ggaacaggat aaagagcaca catgtgagac gctgctgatg tgcattgtca 7700

 ccgtgctgag tcacgggctg cggagcgggg gtggagtagg agatgtactc 7750

 aggaaaccgt ccaaagagga acccctgttt gctgctagag ttatttatga 7800

 cctcttgttc ttcttcatgg tcatcatcat tgttcttaac ctgatttttg 7850

 gggttatcat tgacactttt gctgacctga ggagtgagaa gcagaagaag 7900

 gaagagatct tgaagaccac gtgctttatc tgtggcttgg aaagagacaa 7950

 gtttgacaac aagactgtca cctttgaaga gcacatcaag gaagaacaca 8000

 acatgtggca ctatctgtgc ttcatcgtcc tggtgaaagt aaaggactcc 8050

 accgaatata ctgggcctga gagttacgtg gcagaaatga tcaaggaaag 8100

 aaaccttgac tggttcccca ggatgagagc catgtcattg gtcagcagtg 8150

 attctgaagg agaacagaat gagctgagaa acctgcagga gaagctggag 8200

 tccaccatga aacttgtcac gaacctttct ggccagctgt cggaattaaa 8250

 ggatcagatg acagaacaaa ggaagcagaa acaaagaatt ggtcttctag 8300

 gacatcctcc tcacatgaat gtcaacccac aacaaccagc ataagcaaat 8350

 gaaagaaagg aattgtattt accttttata attattatta gtgtgggtat 8400

 ggctaatgag ttctgattca cccacgaagg ttacatttat gctgaataca 8450

 tttgtaaata ctcagtttta tactgtatgt atatgattgc tactctaaag 8500

 gtttggatat atgtattgta attagaattg ttggcatgat gacatttcat 8550

 ttgtgccaaa aatattaaaa atgccttttt tggaaggact aacagaaagc 8600

 acctgatttg cacttgaacc agattataga tttaaaagta tatgacatgt 8650

 attttgtatt taaaactaga atagccagta tttatgtttt ttataaaact 8700

 gtgcaatacg aattatgcaa tcacaataca tttgtagctc ccgagtgtcc 8750

 taaagggagt gcacttcttt gaagctggtg tgttaatact atgtaataaa 8800

 tggttaactt tcaaatgatg ctgctgccaa aattatatta atagtgagtt 8850

 tcaggcccct gggcattttg taccatgtaa ttatcctctg gtgatgctgt 8900

 ttctcgttag tggcagtagt gcctccgtct cctagtgata atgctccaag 8950

 tctatgaact gttaaatcag cattcatttt aagaaaagca actttagttt 9000

 caaagatact tttaagcttc taaattgatc atttaaacta tttctttaaa 9050

 taagagagcc aaattagagg ctcatacttt agcttgtgaa gaagataatg 9100

 aattttttaa agggaacttt ctatgcaatg ttcaggataa atcgatactg 9150

 ctggccaatc agtgtcatct cctgggtaaa ttttgatgtc gcattataaa 9200

 gacatgcata attgatggtt tctagattat ctagtccaaa caatagagtt 9250

 tattttttct tcatctgaac caacatgcta cagtagctaa gaagtattaa 9300

 aactatatac atccatataa agatgaaata tgaactatct cattagaagt 9350

 catagttgac cacagacatg ttattcttct gaaagagcca cattttggtt 9400

 ttatttcttg tcacatgatt tcttttcttg atggatgaaa aatatgaaat 9450

 gaaatctttt atatctgttg cctagttttg tacatggatc tcattttaca 9500

 agagaatctc tctgcta 9517

<210> 963
<211> 2000
<212> PRT
<213> Homo sapien

<400> 963
 Met Ser Asp Lys Met Ser Ser Phe Leu His Ile Gly Asp Ile Cys
   1               5                  10                  15

 Ser Leu Tyr Ala Glu Gly Ser Thr Asn Gly Phe Ile Ser Thr Leu
                  20                  25                  30

 Gly Leu Val Asp Asp Arg Cys Val Val Gln Pro Glu Thr Gly Asp
                  35                  40                  45

 Leu Asn Asn Pro Pro Lys Lys Phe Arg Asp Cys Leu Phe Lys Leu
                  50                  55                  60

 Cys Pro Met Asn Arg Tyr Ser Ala Gln Lys Gln Phe Trp Lys Ala
                  65                  70                  75

 Ala Lys Pro Gly Ala Asn Ser Thr Thr Asp Ala Val Leu Leu Asn
                  80                  85                  90

 Lys Leu His His Ala Ala Asp Leu Glu Lys Lys Gln Asn Glu Thr
                  95                 100                 105

 Glu Asn Arg Lys Leu Leu Gly Thr Val Ile Gln Tyr Gly Asn Val
                 110                 115                 120

 Ile Gln Leu Leu His Leu Lys Ser Asn Lys Tyr Leu Thr Val Asn
                 125                 130                 135

 Lys Arg Leu Pro Ala Leu Leu Glu Lys Asn Ala Met Arg Val Thr
                 140                 145                 150

 Leu Asp Glu Ala Gly Asn Glu Gly Ser Trp Phe Tyr Ile Gln Pro
                 155                 160                 165

 Phe Tyr Lys Leu Arg Ser Ile Gly Asp Ser Val Val Ile Gly Asp
                 170                 175                 180

 Lys Val Val Leu Asn Pro Val Asn Ala Gly Gln Pro Leu His Ala
                 185                 190                 195

 Ser Ser His Gln Leu Val Asp Asn Pro Gly Cys Asn Glu Val Asn
                 200                 205                 210

 Ser Val Asn Cys Asn Thr Ser Trp Lys Ile Val Leu Phe Met Lys
                 215                 220                 225

 Trp Ser Asp Asn Lys Asp Asp Ile Leu Lys Gly Gly Asp Val Val
                 230                 235                 240

 Arg Leu Phe His Ala Glu Gln Glu Lys Phe Leu Thr Cys Asp Glu
                 245                 250                 255

 His Arg Lys Lys Gln His Val Phe Leu Arg Thr Thr Gly Arg Gln
                 260                 265                 270

 Ser Ala Thr Ser Ala Thr Ser Ser Lys Ala Leu Trp Glu Val Glu
                 275                 280                 285

 Val Val Gln His Asp Pro Cys Arg Gly Gly Ala Gly Tyr Trp Asn
                 290                 295                 300

 Ser Leu Phe Arg Phe Lys His Leu Ala Thr Gly His Tyr Leu Ala
                 305                 310                 315

 Ala Glu Val Asp Pro Asp Gln Asp Ala Ser Arg Ser Arg Leu Arg
                 320                 325                 330

 Asn Ala Gln Glu Lys Met Val Tyr Ser Leu Val Ser Val Pro Glu
                 335                 340                 345

 Gly Asn Asp Ile Ser Ser Ile Phe Glu Leu Asp Pro Thr Thr Leu
                 350                 355                 360

 Arg Gly Gly Asp Ser Leu Val Pro Arg Asn Ser Tyr Val Arg Leu
                 365                 370                 375

 Arg His Leu Cys Thr Asn Thr Trp Val His Ser Thr Asn Ile Pro
                 380                 385                 390

 Ile Asp Lys Glu Glu Glu Lys Pro Val Met Leu Lys Ile Gly Thr
                 395                 400                 405

 Ser Pro Val Lys Glu Asp Lys Glu Ala Phe Ala Ile Val Pro Val
                 410                 415                 420

 Ser Pro Ala Glu Val Arg Asp Leu Asp Phe Ala Asn Asp Ala Ser
                 425                 430                 435

 Lys Val Leu Gly Ser Ile Ala Gly Lys Leu Glu Lys Gly Thr Ile
                 440                 445                 450

 Thr Gln Asn Glu Arg Arg Ser Val Thr Lys Leu Leu Glu Asp Leu
                 455                 460                 465

 Val Tyr Phe Val Thr Gly Gly Thr Asn Ser Gly Gln Asp Val Leu
                 470                 475                 480

 Glu Val Val Phe Ser Lys Pro Asn Arg Glu Arg Gln Lys Leu Met
                 485                 490                 495

 Arg Glu Gln Asn Ile Leu Lys Gln Ile Phe Lys Leu Leu Gln Ala
                 500                 505                 510

 Pro Phe Thr Asp Cys Gly Asp Gly Pro Met Leu Arg Leu Glu Glu
                 515                 520                 525

 Leu Gly Asp Gln Arg His Ala Pro Phe Arg His Ile Cys Arg Leu
                 530                 535                 540

 Cys Tyr Arg Val Leu Arg His Ser Gln Gln Asp Tyr Arg Lys Asn
                 545                 550                 555

 Gln Glu Tyr Ile Ala Lys Gln Phe Gly Phe Met Gln Lys Gln Ile
                 560                 565                 570

 Gly Tyr Asp Val Leu Ala Glu Asp Thr Ile Thr Ala Leu Leu His
                 575                 580                 585

 Asn Asn Arg Lys Leu Leu Glu Lys His Ile Thr Ala Ala Glu Ile
                 590                 595                 600

 Asp Thr Phe Val Ser Leu Val Arg Lys Asn Arg Glu Pro Arg Phe
                 605                 610                 615

 Leu Asp Tyr Leu Ser Asp Leu Cys Val Ser Met Asn Lys Ser Ile
                 620                 625                 630

 Pro Val Thr Gln Glu Leu Ile Cys Lys Ala Val Leu Asn Pro Thr
                 635                 640                 645

 Asn Ala Asp Ile Leu Ile Glu Thr Lys Leu Val Leu Ser Arg Phe
                 650                 655                 660

 Glu Phe Glu Gly Val Ser Ser Thr Gly Glu Asn Ala Leu Glu Ala
                 665                 670                 675

 Gly Glu Asp Glu Glu Glu Val Trp Leu Phe Trp Arg Asp Ser Asn
                 680                 685                 690

 Lys Glu Ile Arg Ser Lys Ser Val Arg Glu Leu Ala Gln Asp Ala
                 695                 700                 705

 Lys Glu Gly Gln Lys Glu Asp Arg Asp Val Leu Ser Tyr Tyr Arg
                 710                 715                 720

 Tyr Gln Leu Asn Leu Phe Ala Arg Met Cys Leu Asp Arg Gln Tyr
                 725                 730                 735

 Leu Ala Ile Asn Glu Ile Ser Gly Gln Leu Asp Val Asp Leu Ile
                 740                 745                 750

 Leu Arg Cys Met Ser Asp Glu Asn Leu Pro Tyr Asp Leu Arg Ala
                 755                 760                 765

 Ser Phe Cys Arg Leu Met Leu His Met His Val Asp Arg Asp Pro
                 770                 775                 780

 Gln Glu Gln Val Thr Pro Val Lys Tyr Ala Arg Leu Trp Ser Glu
                 785                 790                 795

 Ile Pro Ser Glu Ile Ala Ile Asp Asp Tyr Asp Ser Ser Gly Ala
                 800                 805                 810

 Ser Lys Asp Glu Ile Lys Glu Arg Phe Ala Gln Thr Met Glu Phe
                 815                 820                 825

 Val Glu Glu Tyr Leu Arg Asp Val Val Cys Gln Arg Phe Pro Phe
                 830                 835                 840

 Ser Asp Lys Glu Lys Asn Lys Leu Thr Phe Glu Val Val Asn Leu
                 845                 850                 855

 Ala Arg Asn Leu Ile Tyr Phe Gly Phe Tyr Asn Phe Ser Asp Leu
                 860                 865                 870

 Leu Arg Leu Thr Lys Ile Leu Leu Ala Ile Leu Asp Cys Val His
                 875                 880                 885

 Val Thr Thr Ile Phe Pro Ile Ser Lys Met Ala Lys Gly Glu Glu
                 890                 895                 900

 Asn Lys Gly Ser Asn Val Met Arg Ser Ile His Gly Val Gly Glu
                 905                 910                 915

 Leu Met Thr Gln Val Val Leu Arg Gly Gly Gly Phe Leu Pro Met
                 920                 925                 930

 Thr Pro Met Ala Ala Ala Pro Glu Gly Asn Val Lys Gln Ala Glu
                 935                 940                 945

 Pro Glu Lys Glu Asp Ile Met Val Met Asp Thr Lys Leu Lys Ile
                 950                 955                 960

 Ile Glu Ile Leu Gln Phe Ile Leu Asn Val Arg Leu Asp Tyr Arg
                 965                 970                 975

 Ile Ser Cys Leu Leu Cys Ile Phe Lys Arg Glu Phe Asp Glu Ser
                 980                 985                 990

 Asn Ser Gln Thr Ser Glu Thr Ser Ser Gly Asn Ser Ser Gln Glu
                 995                1000                1005

 Gly Pro Ser Asn Val Pro Gly Ala Leu Asp Phe Glu His Ile Glu
                1010                1015                1020

 Glu Gln Ala Glu Gly Ile Phe Gly Gly Ser Glu Glu Asn Thr Pro
                1025                1030                1035

 Leu Asp Leu Asp Asp His Gly Gly Arg Thr Phe Leu Arg Val Leu
                1040                1045                1050

 Leu His Leu Thr Met His Asp Tyr Pro Pro Leu Val Ser Gly Ala
                1055                1060                1065

 Leu Gln Leu Leu Phe Arg His Phe Ser Gln Arg Gln Glu Val Leu
                1070                1075                1080

 Gln Ala Phe Lys Gln Val Gln Leu Leu Val Thr Ser Gln Asp Val
                1085                1090                1095

 Asp Asn Tyr Lys Gln Ile Lys Gln Asp Leu Asp Gln Leu Arg Ser
                1100                1105                1110

 Ile Val Glu Lys Ser Glu Leu Trp Val Tyr Lys Gly Gln Gly Pro
                1115                1120                1125

 Asp Glu Thr Met Asp Gly Ala Ser Gly Glu Asn Glu His Lys Lys
                1130                1135                1140

 Thr Glu Glu Gly Asn Asn Lys Pro Gln Lys His Glu Ser Thr Ser
                1145                1150                1155

 Ser Tyr Asn Tyr Arg Val Val Lys Glu Ile Leu Ile Arg Leu Ser
                1160                1165                1170

 Lys Leu Cys Val Gln Glu Ser Ala Ser Val Arg Lys Ser Arg Lys
                1175                1180                1185

 Gln Gln Gln Arg Leu Leu Arg Asn Met Gly Ala His Ala Val Val
                1190                1195                1200

 Leu Glu Leu Leu Gln Ile Pro Tyr Glu Lys Ala Glu Asp Thr Lys
                1205                1210                1215

 Met Gln Glu Ile Met Arg Leu Ala His Glu Phe Leu Gln Asn Phe
                1220                1225                1230

 Cys Ala Gly Asn Gln Gln Asn Gln Ala Leu Leu His Lys His Ile
                1235                1240                1245

 Asn Leu Phe Leu Asn Pro Gly Ile Leu Glu Ala Val Thr Met Gln
                1250                1255                1260

 His Ile Phe Met Asn Asn Phe Gln Leu Cys Ser Glu Ile Asn Glu
                1265                1270                1275

 Arg Val Val Gln His Phe Val His Cys Ile Glu Thr His Gly Arg
                1280                1285                1290

 Asn Val Gln Tyr Ile Lys Phe Leu Gln Thr Ile Val Lys Ala Glu
                1295                1300                1305

 Gly Lys Phe Ile Lys Lys Cys Gln Asp Met Val Met Ala Glu Leu
                1310                1315                1320

 Val Asn Ser Gly Glu Asp Val Leu Val Phe Tyr Asn Asp Arg Ala
                1325                1330                1335

 Ser Phe Gln Thr Leu Ile Gln Met Met Arg Ser Glu Arg Asp Arg
                1340                1345                1350

 Met Asp Glu Asn Ser Pro Leu Met Tyr His Ile His Leu Val Glu
                1355                1360                1365

 Leu Leu Ala Val Cys Thr Glu Gly Lys Asn Val Tyr Thr Glu Ile
                1370                1375                1380

 Lys Cys Asn Ser Leu Leu Pro Leu Asp Asp Ile Val Arg Val Val
                1385                1390                1395

 Thr His Glu Asp Cys Ile Pro Glu Val Lys Ile Ala Tyr Ile Asn
                1400                1405                1410

 Phe Leu Asn His Cys Tyr Val Asp Thr Glu Val Glu Met Lys Glu
                1415                1420                1425

 Ile Tyr Thr Ser Asn His Met Trp Lys Leu Phe Glu Asn Phe Leu
                1430                1435                1440

 Val Asp Ile Cys Arg Ala Cys Asn Asn Thr Ser Asp Arg Lys His
                1445                1450                1455

 Ala Asp Ser Ile Leu Glu Lys Tyr Val Thr Glu Ile Val Met Ser
                1460                1465                1470

 Ile Val Thr Thr Phe Phe Ser Ser Pro Phe Ser Asp Gln Ser Thr
                1475                1480                1485

 Thr Leu Gln Thr Arg Gln Pro Val Phe Val Gln Leu Leu Gln Gly
                1490                1495                1500

 Val Phe Arg Val Tyr His Cys Asn Trp Leu Met Pro Ser Gln Lys
                1505                1510                1515

 Ala Ser Val Glu Ser Cys Ile Arg Val Leu Ser Asp Val Ala Lys
                1520                1525                1530

 Ser Arg Ala Ile Ala Ile Pro Val Asp Leu Asp Ser Gln Val Asn
                1535                1540                1545

 Asn Leu Phe Leu Lys Ser His Ser Ile Val Gln Lys Thr Ala Met
                1550                1555                1560

 Asn Trp Arg Leu Ser Ala Arg Asn Ala Ala Arg Arg Asp Ser Val
                1565                1570                1575

 Leu Ala Ala Ser Arg Asp Tyr Arg Asn Ile Ile Glu Arg Leu Gln
                1580                1585                1590

 Asp Ile Val Ser Ala Leu Glu Asp Arg Leu Arg Pro Leu Val Gln
                1595                1600                1605

 Ala Glu Leu Ser Val Leu Val Asp Val Leu His Arg Pro Glu Leu
                1610                1615                1620

 Leu Phe Pro Glu Asn Thr Asp Ala Arg Arg Lys Cys Glu Ser Gly
                1625                1630                1635

 Gly Phe Ile Cys Lys Leu Ile Lys His Thr Lys Gln Leu Leu Glu
                1640                1645                1650

 Glu Asn Glu Glu Lys Leu Cys Ile Lys Val Leu Gln Thr Leu Arg
                1655                1660                1665

 Glu Met Met Thr Lys Asp Arg Gly Tyr Gly Glu Lys Gly Glu Ala
                1670                1675                1680

 Leu Arg Gln Val Leu Val Asn Arg Tyr Tyr Gly Asn Val Arg Pro
                1685                1690                1695

 Ser Gly Arg Arg Glu Ser Leu Thr Ser Phe Gly Asn Gly Pro Leu
                1700                1705                1710

 Ser Ala Gly Gly Pro Gly Lys Pro Gly Gly Gly Gly Gly Gly Ser
                1715                1720                1725

 Gly Ser Ser Ser Met Ser Arg Gly Glu Met Ser Leu Ala Glu Val
                1730                1735                1740

 Gln Cys His Leu Asp Lys Glu Gly Ala Ser Asn Leu Val Ile Asp
                1745                1750                1755

 Leu Ile Met Asn Ala Ser Ser Asp Arg Val Phe His Glu Ser Ile
                1760                1765                1770

 Leu Leu Ala Ile Ala Leu Leu Glu Gly Gly Asn Thr Thr Ile Gln
                1775                1780                1785

 His Ser Phe Phe Cys Arg Leu Thr Glu Asp Lys Lys Ser Glu Lys
                1790                1795                1800

 Phe Phe Lys Val Phe Tyr Asp Arg Met Lys Val Ala Gln Gln Glu
                1805                1810                1815

 Ile Lys Ala Thr Val Thr Val Asn Thr Ser Asp Leu Gly Asn Lys
                1820                1825                1830

 Lys Lys Asp Asp Glu Val Asp Arg Asp Ala Pro Ser Arg Lys Lys
                1835                1840                1845

 Ala Lys Glu Pro Thr Thr Gln Ile Thr Glu Glu Val Arg Asp Gln
                1850                1855                1860

 Leu Leu Glu Ala Ser Ala Ala Thr Arg Lys Ala Phe Thr Thr Phe
                1865                1870                1875

 Arg Arg Glu Ala Asp Pro Asp Asp His Tyr Gln Pro Gly Glu Gly
                1880                1885                1890

 Thr Gln Ala Thr Ala Asp Lys Ala Lys Asp Asp Leu Glu Met Ser
                1895                1900                1905

 Ala Val Ile Thr Ile Met Gln Pro Ile Leu Arg Phe Leu Gln Leu
                1910                1915                1920

 Leu Cys Glu Asn His Asn Arg Asp Leu Gln Asn Phe Leu Arg Cys
                1925                1930                1935

 Gln Asn Asn Lys Thr Asn Tyr Asn Leu Val Cys Glu Thr Leu Gln
                1940                1945                1950

 Phe Leu Asp Cys Ile Cys Gly Ser Thr Thr Gly Gly Leu Gly Leu
                1955                1960                1965

 Leu Gly Leu Tyr Ile Asn Glu Lys Asn Val Ala Leu Ile Asn Gln
                1970                1975                1980

 Thr Leu Glu Ser Leu Thr Glu Tyr Cys Gln Gly Pro Cys His Glu
                1985                1990                1995

 Asn Gln Asn Cys Ile
                2000

<210> 964
<211> 2220
<212> DNA
<213> Homo sapien

<400> 964
 cccacgcgtc cgatggaagt taaagggaaa aagcaattca caggaaagaa 50

 tacaaagaca gcacaagaaa aaaacagatt tcataaaaat agtgattctg 100

 gttcttcaaa gacatttcca acaaggaaag ttgctaaaga aggtggacct 150

 aaagtcacat ctaggaactt tgagaaaagt atcacaaaac ttgggaaaaa 200

 gggtgtaaag cagttcaaga ataagcagca aggggacaaa tcaccaaaga 250

 acaaattcca gccggcaaat aaattcaaca agaagagaaa attccagcca 300

 gatggtagaa gcgatgaatc agcagccaag aagcccaaat gggatgactt 350

 caaaaagaag aagaaagaac tgaagcaaag cagacaactc agtgataaaa 400

 ccaactatga cattgttgtt cgggcaaagc agatgtggga gattttaaga 450

 agaaaagact gtgacaaaga aaaaagagta aagttaatga gtgatttgca 500

 gaagttgatt caagggaaaa ttaaaactat tgcatttgca cacgattcaa 550

 ctcgtgtgat ccagtgttac attcagtatg gtaatgaaga acagagaaaa 600

 caggcttttg aagaattgcg agatgatttg gttgagttaa gtaaagccaa 650

 atattcgaga aatattgtta agaaatttct catgtatgga agtaaaccac 700

 agattgcaga gataatcaga agttttaaag gccacgtgag gaagatgctg 750

 cggcatgcgg aagcatcagc catcgtggag tacgcataca atgacaaagc 800

 cattttggag cagaggaaca tgctgacgga agagctctat gggaacacat 850

 ttcagcttta caagtcagca gatcacccaa ctctggacaa agtgttagag 900

 ttacagccag aaaaattaga acttattatg gatgaaatga aacagattct 950

 aactccaatg gcccaaaagg aagctgtgat taagcactca ttggtgcata 1000

 aagtattctt ggactttttt acctatgcac cccccaaact cagatcagaa 1050

 atgattgaag ccatccgcga agcggtggtc tacctggcac acacacacga 1100

 tggcgccaga gtggccatgc actgcctgtg gcatggcacg cccaaggaca 1150

 ggaaagtgat tgtgaaaaca atgaagactt atgttgaaaa ggtggctaat 1200

 ggccaatact cccatttggt tttactggcg gcatttgatt gtattgatga 1250

 tactaagctt gtgaagcaga taatcatatc agaaattatc agttcattgc 1300

 ctagcatagt aaatgacaaa tatggaagga aggtcctatt gtacttacta 1350

 agccccagag atcctgcaca tacagtacga gaaatcattg aagttctgca 1400

 aaaaggagat ggaaatgcac acagtaagaa agatacagag gtccgcagac 1450

 gggagctcct agaatccatt tctccagctt tgttaagcta cctgcaagaa 1500

 cacgcccaag aagtggtgct agataagtct gcgtgtgtgt tggtgtctga 1550

 cattctggga tctgccactg gagacgttca gcctaccatg aatgccatcg 1600

 ccagcttggc agcaacagga ctgcatcctg gtggcaagga cggagagctt 1650

 cacattgcag aacatcctgc aggacatcta gttctgaagt ggttaataga 1700

 gcaagataaa aagatgaaag aaaatgggag agaaggttgt tttgcaaaaa 1750

 cacttgtaga gcatgttggt atgaagaacc tgaagtcctg ggctagtgta 1800

 aatcgaggtg ccattattct ttctagcctc ctccagagtt gtgacctgga 1850

 agttgcaaac aaagtcaaag ctgcactgaa aagcttgatt cctacattgg 1900

 aaaaaaccaa aagcaccagc aaaggaatag aaattctact tgaaaaactg 1950

 agcacatagg tggaaagagt taagagcaag atggaatgat tttttctgtt 2000

 ctctgttctg tttcccaatg cagaaaagaa ggggtagggt ccaccatact 2050

 ggtaattggg gtactctgta tatgtgtttc ttctttgtat acgaatctat 2100

 ttatataaat tgttttttta aatggtcttt tttaaaaaaa aaaaaaaaaa 2150

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2200

 aaaaaaaaaa aaaaaaaaaa 2220

<210> 965
<211> 508
<212> PRT
<213> Homo sapien

<400> 965
 Met Trp Glu Ile Leu Arg Arg Lys Asp Cys Asp Lys Glu Lys Arg
   1               5                  10                  15

 Val Lys Leu Met Ser Asp Leu Gln Lys Leu Ile Gln Gly Lys Ile
                  20                  25                  30

 Lys Thr Ile Ala Phe Ala His Asp Ser Thr Arg Val Ile Gln Cys
                  35                  40                  45

 Tyr Ile Gln Tyr Gly Asn Glu Glu Gln Arg Lys Gln Ala Phe Glu
                  50                  55                  60

 Glu Leu Arg Asp Asp Leu Val Glu Leu Ser Lys Ala Lys Tyr Ser
                  65                  70                  75

 Arg Asn Ile Val Lys Lys Phe Leu Met Tyr Gly Ser Lys Pro Gln
                  80                  85                  90

 Ile Ala Glu Ile Ile Arg Ser Phe Lys Gly His Val Arg Lys Met
                  95                 100                 105

 Leu Arg His Ala Glu Ala Ser Ala Ile Val Glu Tyr Ala Tyr Asn
                 110                 115                 120

 Asp Lys Ala Ile Leu Glu Gln Arg Asn Met Leu Thr Glu Glu Leu
                 125                 130                 135

 Tyr Gly Asn Thr Phe Gln Leu Tyr Lys Ser Ala Asp His Pro Thr
                 140                 145                 150

 Leu Asp Lys Val Leu Glu Leu Gln Pro Glu Lys Leu Glu Leu Ile
                 155                 160                 165

 Met Asp Glu Met Lys Gln Ile Leu Thr Pro Met Ala Gln Lys Glu
                 170                 175                 180

 Ala Val Ile Lys His Ser Leu Val His Lys Val Phe Leu Asp Phe
                 185                 190                 195

 Phe Thr Tyr Ala Pro Pro Lys Leu Arg Ser Glu Met Ile Glu Ala
                 200                 205                 210

 Ile Arg Glu Ala Val Val Tyr Leu Ala His Thr His Asp Gly Ala
                 215                 220                 225

 Arg Val Ala Met His Cys Leu Trp His Gly Thr Pro Lys Asp Arg
                 230                 235                 240

 Lys Val Ile Val Lys Thr Met Lys Thr Tyr Val Glu Lys Val Ala
                 245                 250                 255

 Asn Gly Gln Tyr Ser His Leu Val Leu Leu Ala Ala Phe Asp Cys
                 260                 265                 270

 Ile Asp Asp Thr Lys Leu Val Lys Gln Ile Ile Ile Ser Glu Ile
                 275                 280                 285

 Ile Ser Ser Leu Pro Ser Ile Val Asn Asp Lys Tyr Gly Arg Lys
                 290                 295                 300

 Val Leu Leu Tyr Leu Leu Ser Pro Arg Asp Pro Ala His Thr Val
                 305                 310                 315

 Arg Glu Ile Ile Glu Val Leu Gln Lys Gly Asp Gly Asn Ala His
                 320                 325                 330

 Ser Lys Lys Asp Thr Glu Val Arg Arg Arg Glu Leu Leu Glu Ser
                 335                 340                 345

 Ile Ser Pro Ala Leu Leu Ser Tyr Leu Gln Glu His Ala Gln Glu
                 350                 355                 360

 Val Val Leu Asp Lys Ser Ala Cys Val Leu Val Ser Asp Ile Leu
                 365                 370                 375

 Gly Ser Ala Thr Gly Asp Val Gln Pro Thr Met Asn Ala Ile Ala
                 380                 385                 390

 Ser Leu Ala Ala Thr Gly Leu His Pro Gly Gly Lys Asp Gly Glu
                 395                 400                 405

 Leu His Ile Ala Glu His Pro Ala Gly His Leu Val Leu Lys Trp
                 410                 415                 420

 Leu Ile Glu Gln Asp Lys Lys Met Lys Glu Asn Gly Arg Glu Gly
                 425                 430                 435

 Cys Phe Ala Lys Thr Leu Val Glu His Val Gly Met Lys Asn Leu
                 440                 445                 450

 Lys Ser Trp Ala Ser Val Asn Arg Gly Ala Ile Ile Leu Ser Ser
                 455                 460                 465

 Leu Leu Gln Ser Cys Asp Leu Glu Val Ala Asn Lys Val Lys Ala
                 470                 475                 480

 Ala Leu Lys Ser Leu Ile Pro Thr Leu Glu Lys Thr Lys Ser Thr
                 485                 490                 495

 Ser Lys Gly Ile Glu Ile Leu Leu Glu Lys Leu Ser Thr
                 500                 505

<210> 966
<211> 3445
<212> DNA
<213> Homo sapien

<400> 966
 gagtgactcc accgcccgga gcagcggtgc aggacgcgcg tctccgccgc 50

 ccgcggtgac ttctgcctgc gctccttctc tgaacgctca cttccgagga 100

 gacgccgacg atgaagacac cgtggaaggt tcttctggga ctgctgggtg 150

 ctgctgcgct tgtcaccatc atcaccgtgc ccgtggttct gctgaacaaa 200

 ggcacagatg atgctacagc tgacagtcgc aaaacttaca ctctaactga 250

 ttacttaaaa aatacttata gactgaagtt atactcctta agatggattt 300

 cagatcatga atatctctac aaacaagaaa ataatatctt ggtattcaat 350

 gctgaatatg gaaacagctc agttttcttg gagaacagta catttgatga 400

 gtttggacat tctatcaatg attattcaat atctcctgat gggcagttta 450

 ttctcttaga atacaactac gtgaagcaat ggaggcattc ctacacagct 500

 tcatatgaca tttatgattt aaataaaagg cagctgatta cagaagagag 550

 gattccaaac aacacacagt gggtcacatg gtcaccagtg ggtcataaat 600

 tggcatatgt ttggaacaat gacatttatg ttaaaattga accaaattta 650

 ccaagttaca gaatcacatg gacggggaaa gaagatataa tatataatgg 700

 aataactgac tgggtttatg aagaggaagt cttcagtgcc tactctgctc 750

 tgtggtggtc tccaaacggc acttttttag catatgccca atttaacgac 800

 acagaagtcc cacttattga atactccttc tactctgatg agtcactgca 850

 gtacccaaag actgtacggg ttccatatcc aaaggcagga gctgtgaatc 900

 caactgtaaa gttctttgtt gtaaatacag actctctcag ctcagtcacc 950

 aatgcaactt ccatacaaat cactgctcct gcttctatgt tgatagggga 1000

 tcactacttg tgtgatgtga catgggcaac acaagaaaga atttctttgc 1050

 agtggctcag gaggattcag aactattcgg tcatggatat ttgtgactat 1100

 gatgaatcca gtggaagatg gaactgctta gtggcacggc aacacattga 1150

 aatgagtact actggctggg ttggaagatt taggccttca gaacctcatt 1200

 ttacccttga tggtaatagc ttctacaaga tcatcagcaa tgaagaaggt 1250

 tacagacaca tttgctattt ccaaatagat aaaaaagact gcacatttat 1300

 tacaaaaggc acctgggaag tcatcgggat agaagctcta accagtgatt 1350

 atctatacta cattagtaat gaatataaag gaatgccagg aggaaggaat 1400

 ctttataaaa tccaacttag tgactataca aaagtgacat gcctcagttg 1450

 tgagctgaat ccggaaaggt gtcagtacta ttctgtgtca ttcagtaaag 1500

 aggcgaagta ttatcagctg agatgttccg gtcctggtct gcccctctat 1550

 actctacaca gcagcgtgaa tgataaaggg ctgagagtcc tggaagacaa 1600

 ttcagctttg gataaaatgc tgcagaatgt ccagatgccc tccaaaaaac 1650

 tggacttcat tattttgaat gaaacaaaat tttggtatca gatgatcttg 1700

 cctcctcatt ttgataaatc caagaaatat cctctactat tagatgtgta 1750

 tgcaggccca tgtagtcaaa aagcagacac tgtcttcaga ctgaactggg 1800

 ccacttacct tgcaagcaca gaaaacatta tagtagctag ctttgatggc 1850

 agaggaagtg gttaccaagg agataagatc atgcatgcaa tcaacagaag 1900

 actgggaaca tttgaagttg aagatcaaat tgaagcagcc agacaatttt 1950

 caaaaatggg atttgtggac aacaaacgaa ttgcaatttg gggctggtca 2000

 tatggagggt acgtaacctc aatggtcctg ggatcgggaa gtggcgtgtt 2050

 caagtgtgga atagccgtgg cgcctgtatc ccggtgggag tactatgact 2100

 cagtgtacac agaacgttac atgggtctcc caactccaga agacaacctt 2150

 gaccattaca gaaattcaac agtcatgagc agagctgaaa attttaaaca 2200

 agttgagtac ctccttattc atggaacagc agatgataac gttcactttc 2250

 agcagtcagc tcagatctcc aaagccctgg tcgatgttgg agtggatttc 2300

 caggcaatgt ggtatactga tgaagaccat ggaatagcta gcagcacagc 2350

 acaccaacat atatataccc acatgagcca cttcataaaa caatgtttct 2400

 ctttacctta gcacctcaaa ataccatgcc atttaaagct tattaaaact 2450

 catttttgtt ttcattatct caaaactgca ctgtcaagat gatgatgatc 2500

 tttaaaatac acactcaaat caagaaactt aaggttacct ttgttcccaa 2550

 atttcatacc tatcatctta agtagggact tctgtcttca caacagatta 2600

 ttaccttaca gaagtttgaa ttatccggtc gggttttatt gtttaaaatc 2650

 atttctgcat cagctgctga aacaacaaat aggaattgtt tttatggagg 2700

 ctttgcatag attccctgag caggatttta atctttttct aactggactg 2750

 gttcaaatgt tgttctcttc tttaaaggga tggcaagatg tgggcagtga 2800

 tgtcactagg gcagggacag gataagaggg attagggaga gaagatagca 2850

 gggcatggct gggaacccaa gtccaagcat accaacacga gcaggctact 2900

 gtcagctccc ctcggagaag agctgttcac agccagactg gcacagtttt 2950

 ctgagaaaga ctattcaaac agtctcagga aatcaaatat gcaaagcact 3000

 gacttctaag taaaaccaca gcagttgaaa agactccaaa gaaatgtaag 3050

 ggaaactgcc agcaacgcag gcccccaggt gccagttatg gctataggtg 3100

 ctacaaaaac acagcaaggg tgatgggaaa gcattgtaaa tgtgctttta 3150

 aaaaaaaata ctgatgttcc tagtgaaaga ggcagcttga aactgagatg 3200

 tgaacacatc agcttgccct gttaaaagat gaaaatattt gtatcacaaa 3250

 tcttaacttg aaggagtcct tgcatcaatt tttcttattt catttctttg 3300

 agtgtcttaa ttaaaagaat attttaactt ccttggactc attttaaaaa 3350

 atggaacata aaatacaatg ttatgtatta ttattcccat tctacatact 3400

 atggaatttc tcccagtcat ttaataaatg tgccttcatt ttttc 3445

<210> 967
<211> 766
<212> PRT
<213> Homo sapien

<400> 967
 Met Lys Thr Pro Trp Lys Val Leu Leu Gly Leu Leu Gly Ala Ala
   1               5                  10                  15

 Ala Leu Val Thr Ile Ile Thr Val Pro Val Val Leu Leu Asn Lys
                  20                  25                  30

 Gly Thr Asp Asp Ala Thr Ala Asp Ser Arg Lys Thr Tyr Thr Leu
                  35                  40                  45

 Thr Asp Tyr Leu Lys Asn Thr Tyr Arg Leu Lys Leu Tyr Ser Leu
                  50                  55                  60

 Arg Trp Ile Ser Asp His Glu Tyr Leu Tyr Lys Gln Glu Asn Asn
                  65                  70                  75

 Ile Leu Val Phe Asn Ala Glu Tyr Gly Asn Ser Ser Val Phe Leu
                  80                  85                  90

 Glu Asn Ser Thr Phe Asp Glu Phe Gly His Ser Ile Asn Asp Tyr
                  95                 100                 105

 Ser Ile Ser Pro Asp Gly Gln Phe Ile Leu Leu Glu Tyr Asn Tyr
                 110                 115                 120

 Val Lys Gln Trp Arg His Ser Tyr Thr Ala Ser Tyr Asp Ile Tyr
                 125                 130                 135

 Asp Leu Asn Lys Arg Gln Leu Ile Thr Glu Glu Arg Ile Pro Asn
                 140                 145                 150

 Asn Thr Gln Trp Val Thr Trp Ser Pro Val Gly His Lys Leu Ala
                 155                 160                 165

 Tyr Val Trp Asn Asn Asp Ile Tyr Val Lys Ile Glu Pro Asn Leu
                 170                 175                 180

 Pro Ser Tyr Arg Ile Thr Trp Thr Gly Lys Glu Asp Ile Ile Tyr
                 185                 190                 195

 Asn Gly Ile Thr Asp Trp Val Tyr Glu Glu Glu Val Phe Ser Ala
                 200                 205                 210

 Tyr Ser Ala Leu Trp Trp Ser Pro Asn Gly Thr Phe Leu Ala Tyr
                 215                 220                 225

 Ala Gln Phe Asn Asp Thr Glu Val Pro Leu Ile Glu Tyr Ser Phe
                 230                 235                 240

 Tyr Ser Asp Glu Ser Leu Gln Tyr Pro Lys Thr Val Arg Val Pro
                 245                 250                 255

 Tyr Pro Lys Ala Gly Ala Val Asn Pro Thr Val Lys Phe Phe Val
                 260                 265                 270

 Val Asn Thr Asp Ser Leu Ser Ser Val Thr Asn Ala Thr Ser Ile
                 275                 280                 285

 Gln Ile Thr Ala Pro Ala Ser Met Leu Ile Gly Asp His Tyr Leu
                 290                 295                 300

 Cys Asp Val Thr Trp Ala Thr Gln Glu Arg Ile Ser Leu Gln Trp
                 305                 310                 315

 Leu Arg Arg Ile Gln Asn Tyr Ser Val Met Asp Ile Cys Asp Tyr
                 320                 325                 330

 Asp Glu Ser Ser Gly Arg Trp Asn Cys Leu Val Ala Arg Gln His
                 335                 340                 345

 Ile Glu Met Ser Thr Thr Gly Trp Val Gly Arg Phe Arg Pro Ser
                 350                 355                 360

 Glu Pro His Phe Thr Leu Asp Gly Asn Ser Phe Tyr Lys Ile Ile
                 365                 370                 375

 Ser Asn Glu Glu Gly Tyr Arg His Ile Cys Tyr Phe Gln Ile Asp
                 380                 385                 390

 Lys Lys Asp Cys Thr Phe Ile Thr Lys Gly Thr Trp Glu Val Ile
                 395                 400                 405

 Gly Ile Glu Ala Leu Thr Ser Asp Tyr Leu Tyr Tyr Ile Ser Asn
                 410                 415                 420

 Glu Tyr Lys Gly Met Pro Gly Gly Arg Asn Leu Tyr Lys Ile Gln
                 425                 430                 435

 Leu Ser Asp Tyr Thr Lys Val Thr Cys Leu Ser Cys Glu Leu Asn
                 440                 445                 450

 Pro Glu Arg Cys Gln Tyr Tyr Ser Val Ser Phe Ser Lys Glu Ala
                 455                 460                 465

 Lys Tyr Tyr Gln Leu Arg Cys Ser Gly Pro Gly Leu Pro Leu Tyr
                 470                 475                 480

 Thr Leu His Ser Ser Val Asn Asp Lys Gly Leu Arg Val Leu Glu
                 485                 490                 495

 Asp Asn Ser Ala Leu Asp Lys Met Leu Gln Asn Val Gln Met Pro
                 500                 505                 510

 Ser Lys Lys Leu Asp Phe Ile Ile Leu Asn Glu Thr Lys Phe Trp
                 515                 520                 525

 Tyr Gln Met Ile Leu Pro Pro His Phe Asp Lys Ser Lys Lys Tyr
                 530                 535                 540

 Pro Leu Leu Leu Asp Val Tyr Ala Gly Pro Cys Ser Gln Lys Ala
                 545                 550                 555

 Asp Thr Val Phe Arg Leu Asn Trp Ala Thr Tyr Leu Ala Ser Thr
                 560                 565                 570

 Glu Asn Ile Ile Val Ala Ser Phe Asp Gly Arg Gly Ser Gly Tyr
                 575                 580                 585

 Gln Gly Asp Lys Ile Met His Ala Ile Asn Arg Arg Leu Gly Thr
                 590                 595                 600

 Phe Glu Val Glu Asp Gln Ile Glu Ala Ala Arg Gln Phe Ser Lys
                 605                 610                 615

 Met Gly Phe Val Asp Asn Lys Arg Ile Ala Ile Trp Gly Trp Ser
                 620                 625                 630

 Tyr Gly Gly Tyr Val Thr Ser Met Val Leu Gly Ser Gly Ser Gly
                 635                 640                 645

 Val Phe Lys Cys Gly Ile Ala Val Ala Pro Val Ser Arg Trp Glu
                 650                 655                 660

 Tyr Tyr Asp Ser Val Tyr Thr Glu Arg Tyr Met Gly Leu Pro Thr
                 665                 670                 675

 Pro Glu Asp Asn Leu Asp His Tyr Arg Asn Ser Thr Val Met Ser
                 680                 685                 690

 Arg Ala Glu Asn Phe Lys Gln Val Glu Tyr Leu Leu Ile His Gly
                 695                 700                 705

 Thr Ala Asp Asp Asn Val His Phe Gln Gln Ser Ala Gln Ile Ser
                 710                 715                 720

 Lys Ala Leu Val Asp Val Gly Val Asp Phe Gln Ala Met Trp Tyr
                 725                 730                 735

 Thr Asp Glu Asp His Gly Ile Ala Ser Ser Thr Ala His Gln His
                 740                 745                 750

 Ile Tyr Thr His Met Ser His Phe Ile Lys Gln Cys Phe Ser Leu
                 755                 760                 765

 Pro


<210> 968
<211> 1355
<212> DNA
<213> Homo sapien

<400> 968
 cagtggctgg taggcagtgg ctgggaggca gcggcccaat tagtgtcgtg 50

 cggcccgtgg cgaggcgagg tccggggagc gagcgagcaa gcaaggcggg 100

 aggggtggcc ggagctgcgg cggctggcac aggaggagga gcccgggcgg 150

 gcgaggggcg gccggagagc gccagggcct gagctgccgg agcggcgcct 200

 gtgagtgagt gcagaaagca ggcgcccgcg cgctagccgt ggcaggagca 250

 gcccgcacgc cgcgctctct ccctgggcga cctgcagttt gcaatatgac 300

 tttggaggaa ttctcggctg gagagcagaa gaccgaaagg atggataagg 350

 tgggggatgc cctggaggaa gtgctcagca aagccctgag tcagcgcacg 400

 atcactgtcg gggtgtacga agcggccaag ctgctcaacg tcgaccccga 450

 taacgtggtg ttgtgcctgc tggcggcgga cgaggacgac gacagagatg 500

 tggctctgca gatccacttc accctgatcc aggcgttttg ctgcgagaac 550

 gacatcaaca tcctgcgcgt cagcaacccg ggccggctgg cggagctcct 600

 gctcttggag accgacgctg gccccgcggc gagcgagggc gccgagcagc 650

 ccccggacct gcactgcgtg ctggtgacga atccacattc atctcaatgg 700

 aaggatcctg ccttaagtca acttatttgt ttttgccggg aaagtcgcta 750

 catggatcaa tgggttccag tgattaatct ccctgaacgg tgatggcatc 800

 tgaatgaaaa taactgaacc aaattgcact gaagtttttg aaataccttt 850

 gtagttactc aagcagttac tccctacact gatgcaagga ttacagaaac 900

 tgatgccaag gggctgagtg agttcaacta catgttctgg gggcccggag 950

 atagatgact ttgcagatgg aaagaggtga aaatgaagaa ggaagctgtg 1000

 ttgaaacaga aaaataagtc aaaaggaaca aaaattacaa agaaccatgc 1050

 aggaaggaaa actatgtatt aatttagaat ggttgagtta cattaaaata 1100

 aaccaaatat gttaaagttt aagtgtgcag ccatagtttg ggtatttttg 1150

 gtttatatgc cctcaagtaa aagaaaagcc gaaagggtta atcatatttg 1200

 aaaaccatat tttattgtat tttgatgaga tattaaattc tcaaagtttt 1250

 attataaatt ctactaagtt attttatgac atgaaaagtt atttatgcta 1300

 taaatttttt gaaacacaat acctacaata aactggtatg aataattgca 1350

 tcatt 1355

<210> 969
<211> 165
<212> PRT
<213> Homo sapien

<400> 969
 Met Thr Leu Glu Glu Phe Ser Ala Gly Glu Gln Lys Thr Glu Arg
   1               5                  10                  15

 Met Asp Lys Val Gly Asp Ala Leu Glu Glu Val Leu Ser Lys Ala
                  20                  25                  30

 Leu Ser Gln Arg Thr Ile Thr Val Gly Val Tyr Glu Ala Ala Lys
                  35                  40                  45

 Leu Leu Asn Val Asp Pro Asp Asn Val Val Leu Cys Leu Leu Ala
                  50                  55                  60

 Ala Asp Glu Asp Asp Asp Arg Asp Val Ala Leu Gln Ile His Phe
                  65                  70                  75

 Thr Leu Ile Gln Ala Phe Cys Cys Glu Asn Asp Ile Asn Ile Leu
                  80                  85                  90

 Arg Val Ser Asn Pro Gly Arg Leu Ala Glu Leu Leu Leu Leu Glu
                  95                 100                 105

 Thr Asp Ala Gly Pro Ala Ala Ser Glu Gly Ala Glu Gln Pro Pro
                 110                 115                 120

 Asp Leu His Cys Val Leu Val Thr Asn Pro His Ser Ser Gln Trp
                 125                 130                 135

 Lys Asp Pro Ala Leu Ser Gln Leu Ile Cys Phe Cys Arg Glu Ser
                 140                 145                 150

 Arg Tyr Met Asp Gln Trp Val Pro Val Ile Asn Leu Pro Glu Arg
                 155                 160                 165

<210> 970
<211> 6076
<212> DNA
<213> Homo sapien

<400> 970
 gattcctgca gggagggagg agagaagggc ggcagtggga gggggaggta 50

 cctggaactg ggagtgatgt cagctcccag ctcggtgcct gcccggattc 100

 ctgacatggt gtagtgcagg cagggtgggg aaaggacggg gaaggactcg 150

 tgtgctgcga gctggcggcc gggccggagt gctggggctt tgaactccga 200

 gaggaggtgg accagaactt ttggaactag tgccggcggc tctccacccc 250

 ccagtataaa agaacgtgtg gatcactttg ctgagtacat ccaagatttg 300

 aagaactgaa ataaatcagc tttaaacctg ctttttaaaa atatctgggt 350

 tggaatttgc ccctgacaaa taataaaatg atgagtgatg caagtgacat 400

 gttggctgca gcgttggagc agatggatgg tatcatagca ggttctaagg 450

 ctctggaata ttccaatggg atttttgatt gccaatctcc cacctctcca 500

 ttcatgggaa gtttgcgagc tctgcacctt gtggaagacc tgcgtggatt 550

 gttagagatg atggaaacag atgagaaaga aggcttgaga tgccagatcc 600

 cagattcaac agcagaaacg cttgttgaat ggcttcagag tcaaatgaca 650

 aatggacacc taccagggaa cggagatgtg tatcaagaaa ggctggcacg 700

 tttagaaaat gataaagaat ccctcgttct tcaggtaagt gtgttaacag 750

 accaggtgga ggctcaggga gagaagattc gagatttgga gttttgtctt 800

 gaagagcaca gagagaaggt gaatgccaca gaagaaatgc tgcagcagga 850

 gcttctaagt aggacatcct tagaaactca gaagttggat ctgatggctg 900

 aaatatctaa cttgaagttg aaactgacag ctgtagagaa ggacagattg 950

 gattatgaag ataagttcag agacacagag gggctgattc aggagatcaa 1000

 tgatttgagg ttaaaagtta gtgaaatgga cagtgagaga cttcagtatg 1050

 aaaaaaagct taaatcaacc aaagatgaac tggcatcttt aaaagaacaa 1100

 ctagaagaaa aggaatctga agtaaaaagg ctacaagaaa aattggtttg 1150

 caagatgaaa ggagaagggg ttgaaattgt tgatagagat gaaaatttta 1200

 aaaagaagct caaagaaaaa aacatcgaag tacaaaaaat gaaaaaagct 1250

 gtggagtcct tgatggcagc aaatgaagaa aaggatcgga aaatagaaga 1300

 tcttcgacag tgcctgaaca ggtacaagaa aatgcaagac acggtggtac 1350

 tggcccaagg taaaaaaggc aaagatggag aatatgaaga gctgctcaat 1400

 tccagttcca tctcctcttt gctggatgca cagggtttca gtgatctgga 1450

 gaaaagtcca tcacccactc cagtaatggg atctcccagt tgtgacccat 1500

 ttaacacaag tgttcccgaa gagttccata ctaccatctt gcaagtttcc 1550

 atcccttcat tattgccagc aactgtaagc atggaaactt ctgaaaaatc 1600

 aaagttgact cctaagccag agacttcatt tgaagaaaat gatggaaaca 1650

 taatccttgg tgccactgtt gatacccaac tgtgtgataa acttttaact 1700

 tcaagtctgc agaagtccag cagcctgggc aatctgaaga aagagacatc 1750

 tgatggggaa aaggaaacta ttcagaagac ttcagaggac agagctccgg 1800

 cagaaagcag gccatttggg acccttcctc ccaggccccc agggcaggac 1850

 acctccatgg atgacaaccc cttcggcact cgaaaagtca gatcttcctt 1900

 tggccggggc ttttttaaaa tcaaaagtaa caagagaaca gcaagtgcac 1950

 caaacttaga tcgtaaacga agtgccagtg cacccaccct agctgaaaca 2000

 gaaaaagaga cagcagagca cctagatctg gctggtgctt cttctcggcc 2050

 aaaagattca cagaggaaca gtcccttcca gataccgcct ccatctccag 2100

 attccaaaaa gaaatccaga ggtatcatga aactctttgg aaaacttagg 2150

 agaagtcaat caactacatt caacccagat gacatgtctg agcctgaatt 2200

 caaaagagga gggacaaggg caaccgcggg gccccgatta ggttggtctc 2250

 gagacttggg acagtctaac agtgacttgg atatgccatt tgccaagtgg 2300

 accaaggagc aggtttgcaa ttggctgatg gaacagggct tgggctcgta 2350

 cctgaattct ggcaagcact ggattgcatc tggccaaacg cttttgcagg 2400

 cttctcaaca agatctagag aaggaacttg gaatcaagca ttcacttcat 2450

 cgaaagaaac tccagctagc actccaagcc ctgggatctg aagaagaaac 2500

 caatcatggg aagctggatt tcaactgggt cactagatgg ttggatgaca 2550

 ttggcctccc tcaatataag acccagtttg atgaaggacg ggttgatggt 2600

 cgaatgctac attacatgac tgttgatgac ttactgtctc tgaaggttgt 2650

 aagtgtgcta caccatctca gtatcaaaag ggccatccag gtcctgagga 2700

 tcaataactt tgaaccaaac tgtctacgga ggcggccatc tgatgagaat 2750

 accatcgccc catcagaagt tcagaagtgg actaaccatc gagtgatgga 2800

 gtggctgcgc tccgtggact tggcagaata tgcgcccaat ctcagaggca 2850

 gtggtgtcca tggtgggctc atggttctag agcctcgttt taacgtagaa 2900

 acaatggctc agttattgaa catcccaccc aataagactt tgctgcgaag 2950

 acatttggcc actcatttca accttctgat tggggctgag gcacagcacc 3000

 agaagcgaga tgccatggag ctgccggatt atgtacttct aacagctact 3050

 gccaaagtga agccaaagaa acttgccttt agcaattttg ggaatttgag 3100

 aaagaagaaa caggaagatg gtgaagaata tgtttgtcca atggaattgg 3150

 gacaggcatc aggaagtgca tctaagaaag gatttaaacc tggtttggat 3200

 atgcgcctgt atgaggaaga tgatttggac cggttagagc agatggaaga 3250

 ttcagaaggg acagtgagac agataggtgc attctctgaa ggcatcaaca 3300

 atctgacgca catgttaaaa gaagatgaca tgtttaaaga ttttgctgcc 3350

 cgttccccca gtgccagcat tacagatgaa gactcaaacg tttgaccgta 3400

 gcacctggat gaacattagg agtgcttagt cttttttcta cttgcttttc 3450

 caaacactca cagtatatac aacaggcagc ggattgtcta ttgtttgttg 3500

 ttccaacttc tgctgtcgag aagtttaaac agaaagcagg agtaatgtgc 3550

 cgattctgaa gttgccacaa aaaataagac actggtgaat gagagtataa 3600

 ttgtttttct tctatttaat gtaaaaatct gtgatatatt atatttaaag 3650

 tgttgcattt aagatgagta ttttaccaga gtgtttccat tcatatccgc 3700

 ggtatggagg atttgaggaa cagtaaccag gatgtgaatg attttgttac 3750

 atcagtgttc actgtagcca cctaagtagg acattatatg atttcagaat 3800

 caatatgtgg aacttcttta agcattcagt gtgcccacta aatgccagcc 3850

 acacctccac ttgcctctta ttgtcttatt tttatatatt tttctaaata 3900

 tatgtatata tacagtacat agaaaataga acttttattt tgtgacctaa 3950

 ggacgatggt gaaaagatca cgttttcaaa acaatctggt gatcagaatg 4000

 ttcatatacc agctggtttc tgaagaggtc agaatgatct ttctccatac 4050

 tgacttttaa caatgttgat cattgaggct aaattaatat atatgaaata 4100

 ttcctttttg atgacaccac aaaattgttg aacagtttaa gaatttcaac 4150

 cttaatcttg gatcccttta cctcatatgg aagaacttga gggacattag 4200

 tatacttttt tttaagatgg agtcttgctc tgtcacccag gttggagtgc 4250

 catggcatga tcttggctca ctgcaacctc cacctcctgg gtcaagccat 4300

 tctgcttcag ccccaagtag gtgggactcc aggcatgcac caccatgcct 4350

 ggctaatttt tgcattttta gtagagacag ggtttcacca tattggccag 4400

 gctgggactc gaactcctga ccttgtgatc tgcccgcctc agcctcccaa 4450

 agtactggga ttataggcat gagccaccac gcccagcctg ttattttttt 4500

 attattattg ttttttttta gtgacagagt ctcattctgt tgcccatgct 4550

 ggagtgcagt ggcgtgatca tagctcactg cagccttgaa ttcctaggct 4600

 ccagtgatcc tctcacctca gcttccctaa tagctaggat tacaggtgtg 4650

 tggcctccca ccccacccca cccttcacac ctggctgatt tttcaaaaag 4700

 tttttttgta gaaacagggt ctcaccatgt tgtccagcct ggtctcaaac 4750

 tcctgtcctc aagtgatcct cccacctcag cctttcaaag tgctggaatt 4800

 acaggtgtga gccactctgc ctggcctacc actaacttga atacattcag 4850

 aatcacctcc tctccccaaa atttgtagaa atagtttttg aggaagccaa 4900

 aagcaaagca gaaaccttta cagtattgtt tcttttctct ttgttaactg 4950

 tgtcattaca gcaaaatact agcagtctgc ctaaacatgt tcattgtaca 5000

 tttctcaggc tatcaatgaa tggaggtttt taaaaagttg aatatttgtc 5050

 tgaacatttt atttcaaagt tcaaaaaaac agaggctgca aaattcattt 5100

 tataatggct attttgtgac gataagatgt agttcatgtt tttctgtagc 5150

 actgggccca aatattcttt gtaaagaaaa tcgctgcagc aaaaactgtt 5200

 actgtgttta ttatatttgt agaagtatta gaaaaatatt ctatttttta 5250

 ttcagtgctg cgtaattacc catggtagcc aaccctacaa aagacaggtt 5300

 ttcacaaatt gaggtggagg tgggcggttc agtatctgcc actggacttg 5350

 attataaact gtatttgaat atcagtggta ttatctttta agttgtcagc 5400

 aagttaccaa ggtattcatt aaagaacttg taatatcaaa ttactattta 5450

 ttcataacaa ttgatttgat gctaataata attttcttta aactctacca 5500

 ttcattatgt ggtaactgta ttgaacttac tttatttgga ttttatttta 5550

 atgtgactag atgtcaccac ttcaaaaaat caatttgttc ttagaacctg 5600

 gttgaaaata ccaggaaact gttacagacg ccattttttt tttttttgag 5650

 acggagtctt gctctgttgc ccaggctgga gtgcagtggc acaatctcag 5700

 ctcactgcaa gctccgcctc ctgggttcac gccattctcc cacctcagct 5750

 tcccaagcag ctgggactac aggtacctgc caccacgcct ggctaatttt 5800

 gtttttgtat ttttagtaga gacggggttt caccgtgtta gccaggaagg 5850

 tctcaatctc ctgacctcgt gaatcgcccc cctcggtctc ccaaagtgct 5900

 gggattacag gcgtgagcca ccatgcccgg cccaaatatt ttttattcag 5950

 gatggtataa cctaactgat aataggtaat aaggttaaat ttttttatga 6000

 cgtattttat ttacaaatat catacactgc tggtgttacc atatgaaagg 6050

 aaataaagtc aattgataat tgcctc 6076

<210> 971
<211> 1005
<212> PRT
<213> Homo sapien

<400> 971
 Met Met Ser Asp Ala Ser Asp Met Leu Ala Ala Ala Leu Glu Gln
   1               5                  10                  15

 Met Asp Gly Ile Ile Ala Gly Ser Lys Ala Leu Glu Tyr Ser Asn
                  20                  25                  30

 Gly Ile Phe Asp Cys Gln Ser Pro Thr Ser Pro Phe Met Gly Ser
                  35                  40                  45

 Leu Arg Ala Leu His Leu Val Glu Asp Leu Arg Gly Leu Leu Glu
                  50                  55                  60

 Met Met Glu Thr Asp Glu Lys Glu Gly Leu Arg Cys Gln Ile Pro
                  65                  70                  75

 Asp Ser Thr Ala Glu Thr Leu Val Glu Trp Leu Gln Ser Gln Met
                  80                  85                  90

 Thr Asn Gly His Leu Pro Gly Asn Gly Asp Val Tyr Gln Glu Arg
                  95                 100                 105

 Leu Ala Arg Leu Glu Asn Asp Lys Glu Ser Leu Val Leu Gln Val
                 110                 115                 120

 Ser Val Leu Thr Asp Gln Val Glu Ala Gln Gly Glu Lys Ile Arg
                 125                 130                 135

 Asp Leu Glu Phe Cys Leu Glu Glu His Arg Glu Lys Val Asn Ala
                 140                 145                 150

 Thr Glu Glu Met Leu Gln Gln Glu Leu Leu Ser Arg Thr Ser Leu
                 155                 160                 165

 Glu Thr Gln Lys Leu Asp Leu Met Ala Glu Ile Ser Asn Leu Lys
                 170                 175                 180

 Leu Lys Leu Thr Ala Val Glu Lys Asp Arg Leu Asp Tyr Glu Asp
                 185                 190                 195

 Lys Phe Arg Asp Thr Glu Gly Leu Ile Gln Glu Ile Asn Asp Leu
                 200                 205                 210

 Arg Leu Lys Val Ser Glu Met Asp Ser Glu Arg Leu Gln Tyr Glu
                 215                 220                 225

 Lys Lys Leu Lys Ser Thr Lys Asp Glu Leu Ala Ser Leu Lys Glu
                 230                 235                 240

 Gln Leu Glu Glu Lys Glu Ser Glu Val Lys Arg Leu Gln Glu Lys
                 245                 250                 255

 Leu Val Cys Lys Met Lys Gly Glu Gly Val Glu Ile Val Asp Arg
                 260                 265                 270

 Asp Glu Asn Phe Lys Lys Lys Leu Lys Glu Lys Asn Ile Glu Val
                 275                 280                 285

 Gln Lys Met Lys Lys Ala Val Glu Ser Leu Met Ala Ala Asn Glu
                 290                 295                 300

 Glu Lys Asp Arg Lys Ile Glu Asp Leu Arg Gln Cys Leu Asn Arg
                 305                 310                 315

 Tyr Lys Lys Met Gln Asp Thr Val Val Leu Ala Gln Gly Lys Lys
                 320                 325                 330

 Gly Lys Asp Gly Glu Tyr Glu Glu Leu Leu Asn Ser Ser Ser Ile
                 335                 340                 345

 Ser Ser Leu Leu Asp Ala Gln Gly Phe Ser Asp Leu Glu Lys Ser
                 350                 355                 360

 Pro Ser Pro Thr Pro Val Met Gly Ser Pro Ser Cys Asp Pro Phe
                 365                 370                 375

 Asn Thr Ser Val Pro Glu Glu Phe His Thr Thr Ile Leu Gln Val
                 380                 385                 390

 Ser Ile Pro Ser Leu Leu Pro Ala Thr Val Ser Met Glu Thr Ser
                 395                 400                 405

 Glu Lys Ser Lys Leu Thr Pro Lys Pro Glu Thr Ser Phe Glu Glu
                 410                 415                 420

 Asn Asp Gly Asn Ile Ile Leu Gly Ala Thr Val Asp Thr Gln Leu
                 425                 430                 435

 Cys Asp Lys Leu Leu Thr Ser Ser Leu Gln Lys Ser Ser Ser Leu
                 440                 445                 450

 Gly Asn Leu Lys Lys Glu Thr Ser Asp Gly Glu Lys Glu Thr Ile
                 455                 460                 465

 Gln Lys Thr Ser Glu Asp Arg Ala Pro Ala Glu Ser Arg Pro Phe
                 470                 475                 480

 Gly Thr Leu Pro Pro Arg Pro Pro Gly Gln Asp Thr Ser Met Asp
                 485                 490                 495

 Asp Asn Pro Phe Gly Thr Arg Lys Val Arg Ser Ser Phe Gly Arg
                 500                 505                 510

 Gly Phe Phe Lys Ile Lys Ser Asn Lys Arg Thr Ala Ser Ala Pro
                 515                 520                 525

 Asn Leu Asp Arg Lys Arg Ser Ala Ser Ala Pro Thr Leu Ala Glu
                 530                 535                 540

 Thr Glu Lys Glu Thr Ala Glu His Leu Asp Leu Ala Gly Ala Ser
                 545                 550                 555

 Ser Arg Pro Lys Asp Ser Gln Arg Asn Ser Pro Phe Gln Ile Pro
                 560                 565                 570

 Pro Pro Ser Pro Asp Ser Lys Lys Lys Ser Arg Gly Ile Met Lys
                 575                 580                 585

 Leu Phe Gly Lys Leu Arg Arg Ser Gln Ser Thr Thr Phe Asn Pro
                 590                 595                 600

 Asp Asp Met Ser Glu Pro Glu Phe Lys Arg Gly Gly Thr Arg Ala
                 605                 610                 615

 Thr Ala Gly Pro Arg Leu Gly Trp Ser Arg Asp Leu Gly Gln Ser
                 620                 625                 630

 Asn Ser Asp Leu Asp Met Pro Phe Ala Lys Trp Thr Lys Glu Gln
                 635                 640                 645

 Val Cys Asn Trp Leu Met Glu Gln Gly Leu Gly Ser Tyr Leu Asn
                 650                 655                 660

 Ser Gly Lys His Trp Ile Ala Ser Gly Gln Thr Leu Leu Gln Ala
                 665                 670                 675

 Ser Gln Gln Asp Leu Glu Lys Glu Leu Gly Ile Lys His Ser Leu
                 680                 685                 690

 His Arg Lys Lys Leu Gln Leu Ala Leu Gln Ala Leu Gly Ser Glu
                 695                 700                 705

 Glu Glu Thr Asn His Gly Lys Leu Asp Phe Asn Trp Val Thr Arg
                 710                 715                 720

 Trp Leu Asp Asp Ile Gly Leu Pro Gln Tyr Lys Thr Gln Phe Asp
                 725                 730                 735

 Glu Gly Arg Val Asp Gly Arg Met Leu His Tyr Met Thr Val Asp
                 740                 745                 750

 Asp Leu Leu Ser Leu Lys Val Val Ser Val Leu His His Leu Ser
                 755                 760                 765

 Ile Lys Arg Ala Ile Gln Val Leu Arg Ile Asn Asn Phe Glu Pro
                 770                 775                 780

 Asn Cys Leu Arg Arg Arg Pro Ser Asp Glu Asn Thr Ile Ala Pro
                 785                 790                 795

 Ser Glu Val Gln Lys Trp Thr Asn His Arg Val Met Glu Trp Leu
                 800                 805                 810

 Arg Ser Val Asp Leu Ala Glu Tyr Ala Pro Asn Leu Arg Gly Ser
                 815                 820                 825

 Gly Val His Gly Gly Leu Met Val Leu Glu Pro Arg Phe Asn Val
                 830                 835                 840

 Glu Thr Met Ala Gln Leu Leu Asn Ile Pro Pro Asn Lys Thr Leu
                 845                 850                 855

 Leu Arg Arg His Leu Ala Thr His Phe Asn Leu Leu Ile Gly Ala
                 860                 865                 870

 Glu Ala Gln His Gln Lys Arg Asp Ala Met Glu Leu Pro Asp Tyr
                 875                 880                 885

 Val Leu Leu Thr Ala Thr Ala Lys Val Lys Pro Lys Lys Leu Ala
                 890                 895                 900

 Phe Ser Asn Phe Gly Asn Leu Arg Lys Lys Lys Gln Glu Asp Gly
                 905                 910                 915

 Glu Glu Tyr Val Cys Pro Met Glu Leu Gly Gln Ala Ser Gly Ser
                 920                 925                 930

 Ala Ser Lys Lys Gly Phe Lys Pro Gly Leu Asp Met Arg Leu Tyr
                 935                 940                 945

 Glu Glu Asp Asp Leu Asp Arg Leu Glu Gln Met Glu Asp Ser Glu
                 950                 955                 960

 Gly Thr Val Arg Gln Ile Gly Ala Phe Ser Glu Gly Ile Asn Asn
                 965                 970                 975

 Leu Thr His Met Leu Lys Glu Asp Asp Met Phe Lys Asp Phe Ala
                 980                 985                 990

 Ala Arg Ser Pro Ser Ala Ser Ile Thr Asp Glu Asp Ser Asn Val
                 995                1000                1005

<210> 972
<211> 5361
<212> DNA
<213> Homo sapien

<400> 972
 gccagcgatc agagcagcgc tgggtgttca ggggccaaga tggcggcgcg 50

 ccggggacgg agagacggag tcgcgccgcc cccgagtggg ggccccggtc 100

 cggaccctgg cgggggagcc cgcggcagtg gttggcgaag tcgaagccaa 150

 gcgccgtatg ggactttggg cgctgtgagc ggcggcgagc aggtgctgct 200

 gcatgaggag gcgggtgatt ctggctttgt cagtctctct cggcagggcc 250

 catctctgag ggacaaggac ctggaaatgg aggagctaat gctgcaggat 300

 gagacactgc tggggaccat gcagagctac atggatgcct cccttatctc 350

 cctcattgag gattttggga gccttggaga gagcaggtta tctctggagg 400

 accacaatga agtgtcgctg ctcacggctc tgacggagat cttggacaat 450

 gcagattctg agaacctttc tccatttgac agcattcctg attcggagct 500

 gcttgtgtca ccccgggagg gctcctctct gcacaagctg cttactctct 550

 ctcggacacc cccagaacgt gacctcatca ccccagttga cccactgggg 600

 cccagtacgg gcagcagtag agggagtggg gttgaaatgt ctcttccaga 650

 tccctcttgg gacttctccc caccctcttt cttagagacc tcttccccca 700

 agcttcctag ctggagaccc ccaagatcaa gaccacgctg gggccaatcc 750

 ccacctcccc agcagcgcag tgatggagaa gaagaggagg aggtggccag 800

 cttcagtggc cagattcttg ccggggagct tgacaactgt gtgagcagta 850

 tcccggactt ccccatgcat ttggcctgcc ctgaggagga agataaagca 900

 acagcagcag agatggcagt gccagcagct ggtgatgaga gcatctcctc 950

 cctgagtgag ctggtgcggg ccatgcaccc atactgcctg cccaacctca 1000

 cccacctggc atcacttgag gatgagcttc aggagcagcc agatgatttg 1050

 acactgcctg agggctgcgt agtgctggag attgtggggc aggcagccac 1100

 agctggcgat gacctggaga tcccagttgt ggtgcgacag gtctctcctg 1150

 gaccccggcc tgtgctcctg gatgactcgc tagagactag ttctgccttg 1200

 cagctgctta tgcctacact ggagtcagag acagaggctg ctgtgcccaa 1250

 ggtaaccctc tgctctgaga aagaggggtt gtcattgaac tcagaggaga 1300

 agctggactc agcctgctta ttgaagccca gggaggtcgt ggagccggtg 1350

 gtgcccaagg agcctcagaa cccacctgcc aatgcagcac caggttccca 1400

 gagagctcga aagggcagga agaagaagag caaggagcag ccagcagcct 1450

 gtgtggaagg ctatgccagg aggctgaggt catcttctcg cgggcagtct 1500

 actgtaggta cagaagtgac ctctcaggta gacaacttgc agaaacagcc 1550

 tcaggaagaa cttcaaaaag agtctgggcc tctccagggt aaggggaagc 1600

 cccgggcttg ggctcgggcc tgggcagctg ccttggagaa ttctagccct 1650

 aagaacttgg agagaagtgc tggacaaagt agtcctgcta aagaaggccc 1700

 tctagacctc tacccaaagc tggctgacac tatccaaacc aatcctatac 1750

 caacccatct ctcattggtc gactctgccc aagccagccc catgccagtt 1800

 gactctgttg aagctgatcc cactgcagtt ggccctgttc tagctggccc 1850

 tgtacctgtt gaccctgggt tggttgacct tgcttcaacc agctcagaac 1900

 tggttgagcc tctcccggct gagccagtgc tgatcaaccc agtcctggct 1950

 gactcagcag cagttgaccc tgcagtggtt cccatctcag ataacttgcc 2000

 accagttgat gctgtcccgt ctggcccagc accagttgat ctagcactgg 2050

 ttgaccctgt tcctaatgac ctgactccag ttgacccagt gctagttaag 2100

 tccagaccaa ctgatcccag acgtggtgca gtgtcatcag ccctgggggg 2150

 ttcagcaccc cagctcctcg tggagtcaga gtccttggac ccaccaaaga 2200

 ccatcatccc tgaagtcaaa gaggttgtgg attctctgaa aattgaaagt 2250

 ggtaccagtg ctacaaccca tgaagccaga cctcggcctc tcagcttatc 2300

 tgagtaccgg cgacgaaggc agcaacgcca agcagaaaca gaagagagaa 2350

 gtccacagcc cccaactggg aagtggccta gccttccaga gactcccaca 2400

 gggctggcag acatcccttg tcttgtcatc ccaccagccc cagccaagaa 2450

 gacagctctg cagagaagcc ctgaaacacc ccttgagatt tgccttgtgc 2500

 ctgtaggtcc cagccctgct tctcctagtc ctgagccacc tgtaagcaaa 2550

 cctgtggcct catctcccac tgagcaggtg ccatcccagg agatgccact 2600

 gttggcgaga ccttcccctc ctgtgcagtc tgtgtcccct gctgtgccca 2650

 cacctccctc gatgtctgct gccctgcctt tccctgcagg tgggcttggc 2700

 atgcccccca gtctgccccc acctcccttg cagcctccta gtcttccatt 2750

 gtctatgggg ccagtactac ctgatccgtt tactcactat gcccccttgc 2800

 catcctggcc ttgttatcct catgtgtccc cttctggcta tccttgcctg 2850

 ccccccccac caacggtgcc cctagtgtct ggtactcctg gtgcctatgc 2900

 cgtgcctccc acttgcagtg tgccttgggc accccctcct gccccagtct 2950

 caccttacag ttccacatgt acctatgggc ccttgggatg gggcccaggg 3000

 cctcaacatg ctccattctg gtctactgtt cccccacctc ctttgcctcc 3050

 agcctccatt gggagagctg ttccccaacc taaaatggag tctaggggca 3100

 ctccagctgg ccctcctgaa aatgtacttc ccttgtcgat ggctcctccc 3150

 ctcagtcttg ggctacctgg ccatggagct cctcagacag agcctaccaa 3200

 ggtggaggtc aagccagtgc ctgcatctcc ccatccgaaa cacaaggtgt 3250

 ctgccctggt gcaaagtccc cagatgaagg ctctagcatg tgtgtctgct 3300

 gaaggtgtga ctgttgagga gcctgcatca gagaggctaa agcctgagac 3350

 ccaagagacc aggcccaggg agaagccccc cttgcctgct accaaggctg 3400

 ttcccacacc aaggcagagc actgtcccca agctgcctgc tgtccaccca 3450

 gcccgtctaa ggaagctgtc cttcctgcct accccacgta ctcagggttc 3500

 tgaagatgtg gtacaggctt tcatcagtga gattggaatt gaggcatcgg 3550

 acctgtccag tctgctggag cagtttgaga aatcagaagc caaaaaggag 3600

 tgtcctcctc cggctcctgc tgacagcttg gctgtaggaa actcaggcgg 3650

 cgttgacatt ccccaggaga agaggcccct agaccggtta caagccccag 3700

 aactggccaa cgtggcaggg ctcacccctc cagctacccc tccccaccag 3750

 ttatggaagc ccctggctgc tgtctcactg ctggccaaag ccaaatctcc 3800

 taagtccacc gcccaggagg gaaccctgaa gcctgaagga gttacggagg 3850

 ccaaacatcc agctgcagtt cgcctccaag aaggggtcca tggccctagt 3900

 cgagtccatg tgggctctgg ggaccatgac tattgtgtcc ggagcaggac 3950

 ccccccaaaa aagatgcctg ccctagtcat tccagaggtg ggctcccgat 4000

 ggaatgtcaa gcgccatcag gacatcacca tcaaacctgt cttgtccttg 4050

 ggcccagctg cccctccgcc cccatgcata gctgcctccc gggagccgct 4100

 tgatcacagg actagcagtg agcaggcaga tccctcagca ccctgccttg 4150

 ccccatccag cttgctgtcc cctgaggcct caccctgccg gaatgacatg 4200

 aacactagga ctccccctga accctcagcc aagcagcggt caatgcgctg 4250

 ttaccgaaaa gcctgcaggt cagccagccc ctcaagccag ggctggcagg 4300

 gccgccgagg ccgcaacagc cgttctgtca gctctgggtc caaccggact 4350

 agcgaagcat cttcctcatc ctcatcatcg tcttcctcat cccgatctcg 4400

 gtccaggtcc ctctcccccc cacacaagag gtggcgaagg tccagctgta 4450

 gttcctctgg acgttctcga agatgctctt cctcttcttc gtcatcatct 4500

 tcctcttcgt cttcctcatc ctcatcatcc agttctcgaa gccgctcacg 4550

 atccccatcc ccccgccgga gaagtgacag gaggcggcgg tacagctctt 4600

 atcgttcaca tgaccattac caaaggcaaa gagtgctaca aaaggagcgt 4650

 gcaatagaag aaagaagggt ggtcttcatt ggaaagatac ctggccgcat 4700

 gactcgatca gagctgaaac agaggttctc cgtttttgga gagattgagg 4750

 agtgcaccat ccacttccgt gtccaagggg acaactacgg cttcgtcact 4800

 tatcgctatg ctgaggaggc atttgcagcc attgagagtg gccacaagct 4850

 gcggcaggca gatgagcagc cctttgatct ctgctttggg ggccgaaggc 4900

 agttctgcaa gaggagctat tctgatcttg actccaaccg ggaagacttt 4950

 gacccagcac ctgtaaagag caaatttgat tctcttgact ttgacacatt 5000

 gttgaaacag gcccagaaga acctcaggag gtaaccttgg gcccttccct 5050

 gctatccttt ttctcctttg gaggtgccca acctcctcca cccccttccc 5100

 ctactctagg ggagagagct gctagtgaga tgactgtttt ataaagaaat 5150

 ggaaaaaagt gaaataaaaa atatgttgaa tcagattttt taaaaggggt 5200

 atttgttttt ttataacagg tattgaaaca agttaacttg cattcctatg 5250

 taagatagga ggggctgagg ggatccccag tgtttggaac ataagtcact 5300

 atgcagacta ataaacatca actagagaga gaaaaaaaaa aaaaaaaaaa 5350

 aaaaaaaaaa a 5361

<210> 973
<211> 1664
<212> PRT
<213> Homo sapien

<400> 973
 Met Ala Ala Arg Arg Gly Arg Arg Asp Gly Val Ala Pro Pro Pro
   1               5                  10                  15

 Ser Gly Gly Pro Gly Pro Asp Pro Gly Gly Gly Ala Arg Gly Ser
                  20                  25                  30

 Gly Trp Arg Ser Arg Ser Gln Ala Pro Tyr Gly Thr Leu Gly Ala
                  35                  40                  45

 Val Ser Gly Gly Glu Gln Val Leu Leu His Glu Glu Ala Gly Asp
                  50                  55                  60

 Ser Gly Phe Val Ser Leu Ser Arg Gln Gly Pro Ser Leu Arg Asp
                  65                  70                  75

 Lys Asp Leu Glu Met Glu Glu Leu Met Leu Gln Asp Glu Thr Leu
                  80                  85                  90

 Leu Gly Thr Met Gln Ser Tyr Met Asp Ala Ser Leu Ile Ser Leu
                  95                 100                 105

 Ile Glu Asp Phe Gly Ser Leu Gly Glu Ser Arg Leu Ser Leu Glu
                 110                 115                 120

 Asp His Asn Glu Val Ser Leu Leu Thr Ala Leu Thr Glu Ile Leu
                 125                 130                 135

 Asp Asn Ala Asp Ser Glu Asn Leu Ser Pro Phe Asp Ser Ile Pro
                 140                 145                 150

 Asp Ser Glu Leu Leu Val Ser Pro Arg Glu Gly Ser Ser Leu His
                 155                 160                 165

 Lys Leu Leu Thr Leu Ser Arg Thr Pro Pro Glu Arg Asp Leu Ile
                 170                 175                 180

 Thr Pro Val Asp Pro Leu Gly Pro Ser Thr Gly Ser Ser Arg Gly
                 185                 190                 195

 Ser Gly Val Glu Met Ser Leu Pro Asp Pro Ser Trp Asp Phe Ser
                 200                 205                 210

 Pro Pro Ser Phe Leu Glu Thr Ser Ser Pro Lys Leu Pro Ser Trp
                 215                 220                 225

 Arg Pro Pro Arg Ser Arg Pro Arg Trp Gly Gln Ser Pro Pro Pro
                 230                 235                 240

 Gln Gln Arg Ser Asp Gly Glu Glu Glu Glu Glu Val Ala Ser Phe
                 245                 250                 255

 Ser Gly Gln Ile Leu Ala Gly Glu Leu Asp Asn Cys Val Ser Ser
                 260                 265                 270

 Ile Pro Asp Phe Pro Met His Leu Ala Cys Pro Glu Glu Glu Asp
                 275                 280                 285

 Lys Ala Thr Ala Ala Glu Met Ala Val Pro Ala Ala Gly Asp Glu
                 290                 295                 300

 Ser Ile Ser Ser Leu Ser Glu Leu Val Arg Ala Met His Pro Tyr
                 305                 310                 315

 Cys Leu Pro Asn Leu Thr His Leu Ala Ser Leu Glu Asp Glu Leu
                 320                 325                 330

 Gln Glu Gln Pro Asp Asp Leu Thr Leu Pro Glu Gly Cys Val Val
                 335                 340                 345

 Leu Glu Ile Val Gly Gln Ala Ala Thr Ala Gly Asp Asp Leu Glu
                 350                 355                 360

 Ile Pro Val Val Val Arg Gln Val Ser Pro Gly Pro Arg Pro Val
                 365                 370                 375

 Leu Leu Asp Asp Ser Leu Glu Thr Ser Ser Ala Leu Gln Leu Leu
                 380                 385                 390

 Met Pro Thr Leu Glu Ser Glu Thr Glu Ala Ala Val Pro Lys Val
                 395                 400                 405

 Thr Leu Cys Ser Glu Lys Glu Gly Leu Ser Leu Asn Ser Glu Glu
                 410                 415                 420

 Lys Leu Asp Ser Ala Cys Leu Leu Lys Pro Arg Glu Val Val Glu
                 425                 430                 435

 Pro Val Val Pro Lys Glu Pro Gln Asn Pro Pro Ala Asn Ala Ala
                 440                 445                 450

 Pro Gly Ser Gln Arg Ala Arg Lys Gly Arg Lys Lys Lys Ser Lys
                 455                 460                 465

 Glu Gln Pro Ala Ala Cys Val Glu Gly Tyr Ala Arg Arg Leu Arg
                 470                 475                 480

 Ser Ser Ser Arg Gly Gln Ser Thr Val Gly Thr Glu Val Thr Ser
                 485                 490                 495

 Gln Val Asp Asn Leu Gln Lys Gln Pro Gln Glu Glu Leu Gln Lys
                 500                 505                 510

 Glu Ser Gly Pro Leu Gln Gly Lys Gly Lys Pro Arg Ala Trp Ala
                 515                 520                 525

 Arg Ala Trp Ala Ala Ala Leu Glu Asn Ser Ser Pro Lys Asn Leu
                 530                 535                 540

 Glu Arg Ser Ala Gly Gln Ser Ser Pro Ala Lys Glu Gly Pro Leu
                 545                 550                 555

 Asp Leu Tyr Pro Lys Leu Ala Asp Thr Ile Gln Thr Asn Pro Ile
                 560                 565                 570

 Pro Thr His Leu Ser Leu Val Asp Ser Ala Gln Ala Ser Pro Met
                 575                 580                 585

 Pro Val Asp Ser Val Glu Ala Asp Pro Thr Ala Val Gly Pro Val
                 590                 595                 600

 Leu Ala Gly Pro Val Pro Val Asp Pro Gly Leu Val Asp Leu Ala
                 605                 610                 615

 Ser Thr Ser Ser Glu Leu Val Glu Pro Leu Pro Ala Glu Pro Val
                 620                 625                 630

 Leu Ile Asn Pro Val Leu Ala Asp Ser Ala Ala Val Asp Pro Ala
                 635                 640                 645

 Val Val Pro Ile Ser Asp Asn Leu Pro Pro Val Asp Ala Val Pro
                 650                 655                 660

 Ser Gly Pro Ala Pro Val Asp Leu Ala Leu Val Asp Pro Val Pro
                 665                 670                 675

 Asn Asp Leu Thr Pro Val Asp Pro Val Leu Val Lys Ser Arg Pro
                 680                 685                 690

 Thr Asp Pro Arg Arg Gly Ala Val Ser Ser Ala Leu Gly Gly Ser
                 695                 700                 705

 Ala Pro Gln Leu Leu Val Glu Ser Glu Ser Leu Asp Pro Pro Lys
                 710                 715                 720

 Thr Ile Ile Pro Glu Val Lys Glu Val Val Asp Ser Leu Lys Ile
                 725                 730                 735

 Glu Ser Gly Thr Ser Ala Thr Thr His Glu Ala Arg Pro Arg Pro
                 740                 745                 750

 Leu Ser Leu Ser Glu Tyr Arg Arg Arg Arg Gln Gln Arg Gln Ala
                 755                 760                 765

 Glu Thr Glu Glu Arg Ser Pro Gln Pro Pro Thr Gly Lys Trp Pro
                 770                 775                 780

 Ser Leu Pro Glu Thr Pro Thr Gly Leu Ala Asp Ile Pro Cys Leu
                 785                 790                 795

 Val Ile Pro Pro Ala Pro Ala Lys Lys Thr Ala Leu Gln Arg Ser
                 800                 805                 810

 Pro Glu Thr Pro Leu Glu Ile Cys Leu Val Pro Val Gly Pro Ser
                 815                 820                 825

 Pro Ala Ser Pro Ser Pro Glu Pro Pro Val Ser Lys Pro Val Ala
                 830                 835                 840

 Ser Ser Pro Thr Glu Gln Val Pro Ser Gln Glu Met Pro Leu Leu
                 845                 850                 855

 Ala Arg Pro Ser Pro Pro Val Gln Ser Val Ser Pro Ala Val Pro
                 860                 865                 870

 Thr Pro Pro Ser Met Ser Ala Ala Leu Pro Phe Pro Ala Gly Gly
                 875                 880                 885

 Leu Gly Met Pro Pro Ser Leu Pro Pro Pro Pro Leu Gln Pro Pro
                 890                 895                 900

 Ser Leu Pro Leu Ser Met Gly Pro Val Leu Pro Asp Pro Phe Thr
                 905                 910                 915

 His Tyr Ala Pro Leu Pro Ser Trp Pro Cys Tyr Pro His Val Ser
                 920                 925                 930

 Pro Ser Gly Tyr Pro Cys Leu Pro Pro Pro Pro Thr Val Pro Leu
                 935                 940                 945

 Val Ser Gly Thr Pro Gly Ala Tyr Ala Val Pro Pro Thr Cys Ser
                 950                 955                 960

 Val Pro Trp Ala Pro Pro Pro Ala Pro Val Ser Pro Tyr Ser Ser
                 965                 970                 975

 Thr Cys Thr Tyr Gly Pro Leu Gly Trp Gly Pro Gly Pro Gln His
                 980                 985                 990

 Ala Pro Phe Trp Ser Thr Val Pro Pro Pro Pro Leu Pro Pro Ala
                 995                1000                1005

 Ser Ile Gly Arg Ala Val Pro Gln Pro Lys Met Glu Ser Arg Gly
                1010                1015                1020

 Thr Pro Ala Gly Pro Pro Glu Asn Val Leu Pro Leu Ser Met Ala
                1025                1030                1035

 Pro Pro Leu Ser Leu Gly Leu Pro Gly His Gly Ala Pro Gln Thr
                1040                1045                1050

 Glu Pro Thr Lys Val Glu Val Lys Pro Val Pro Ala Ser Pro His
                1055                1060                1065

 Pro Lys His Lys Val Ser Ala Leu Val Gln Ser Pro Gln Met Lys
                1070                1075                1080

 Ala Leu Ala Cys Val Ser Ala Glu Gly Val Thr Val Glu Glu Pro
                1085                1090                1095

 Ala Ser Glu Arg Leu Lys Pro Glu Thr Gln Glu Thr Arg Pro Arg
                1100                1105                1110

 Glu Lys Pro Pro Leu Pro Ala Thr Lys Ala Val Pro Thr Pro Arg
                1115                1120                1125

 Gln Ser Thr Val Pro Lys Leu Pro Ala Val His Pro Ala Arg Leu
                1130                1135                1140

 Arg Lys Leu Ser Phe Leu Pro Thr Pro Arg Thr Gln Gly Ser Glu
                1145                1150                1155

 Asp Val Val Gln Ala Phe Ile Ser Glu Ile Gly Ile Glu Ala Ser
                1160                1165                1170

 Asp Leu Ser Ser Leu Leu Glu Gln Phe Glu Lys Ser Glu Ala Lys
                1175                1180                1185

 Lys Glu Cys Pro Pro Pro Ala Pro Ala Asp Ser Leu Ala Val Gly
                1190                1195                1200

 Asn Ser Gly Gly Val Asp Ile Pro Gln Glu Lys Arg Pro Leu Asp
                1205                1210                1215

 Arg Leu Gln Ala Pro Glu Leu Ala Asn Val Ala Gly Leu Thr Pro
                1220                1225                1230

 Pro Ala Thr Pro Pro His Gln Leu Trp Lys Pro Leu Ala Ala Val
                1235                1240                1245

 Ser Leu Leu Ala Lys Ala Lys Ser Pro Lys Ser Thr Ala Gln Glu
                1250                1255                1260

 Gly Thr Leu Lys Pro Glu Gly Val Thr Glu Ala Lys His Pro Ala
                1265                1270                1275

 Ala Val Arg Leu Gln Glu Gly Val His Gly Pro Ser Arg Val His
                1280                1285                1290

 Val Gly Ser Gly Asp His Asp Tyr Cys Val Arg Ser Arg Thr Pro
                1295                1300                1305

 Pro Lys Lys Met Pro Ala Leu Val Ile Pro Glu Val Gly Ser Arg
                1310                1315                1320

 Trp Asn Val Lys Arg His Gln Asp Ile Thr Ile Lys Pro Val Leu
                1325                1330                1335

 Ser Leu Gly Pro Ala Ala Pro Pro Pro Pro Cys Ile Ala Ala Ser
                1340                1345                1350

 Arg Glu Pro Leu Asp His Arg Thr Ser Ser Glu Gln Ala Asp Pro
                1355                1360                1365

 Ser Ala Pro Cys Leu Ala Pro Ser Ser Leu Leu Ser Pro Glu Ala
                1370                1375                1380

 Ser Pro Cys Arg Asn Asp Met Asn Thr Arg Thr Pro Pro Glu Pro
                1385                1390                1395

 Ser Ala Lys Gln Arg Ser Met Arg Cys Tyr Arg Lys Ala Cys Arg
                1400                1405                1410

 Ser Ala Ser Pro Ser Ser Gln Gly Trp Gln Gly Arg Arg Gly Arg
                1415                1420                1425

 Asn Ser Arg Ser Val Ser Ser Gly Ser Asn Arg Thr Ser Glu Ala
                1430                1435                1440

 Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Arg Ser Arg Ser
                1445                1450                1455

 Arg Ser Leu Ser Pro Pro His Lys Arg Trp Arg Arg Ser Ser Cys
                1460                1465                1470

 Ser Ser Ser Gly Arg Ser Arg Arg Cys Ser Ser Ser Ser Ser Ser
                1475                1480                1485

 Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Arg
                1490                1495                1500

 Ser Arg Ser Arg Ser Pro Ser Pro Arg Arg Arg Ser Asp Arg Arg
                1505                1510                1515

 Arg Arg Tyr Ser Ser Tyr Arg Ser His Asp His Tyr Gln Arg Gln
                1520                1525                1530

 Arg Val Leu Gln Lys Glu Arg Ala Ile Glu Glu Arg Arg Val Val
                1535                1540                1545

 Phe Ile Gly Lys Ile Pro Gly Arg Met Thr Arg Ser Glu Leu Lys
                1550                1555                1560

 Gln Arg Phe Ser Val Phe Gly Glu Ile Glu Glu Cys Thr Ile His
                1565                1570                1575

 Phe Arg Val Gln Gly Asp Asn Tyr Gly Phe Val Thr Tyr Arg Tyr
                1580                1585                1590

 Ala Glu Glu Ala Phe Ala Ala Ile Glu Ser Gly His Lys Leu Arg
                1595                1600                1605

 Gln Ala Asp Glu Gln Pro Phe Asp Leu Cys Phe Gly Gly Arg Arg
                1610                1615                1620

 Gln Phe Cys Lys Arg Ser Tyr Ser Asp Leu Asp Ser Asn Arg Glu
                1625                1630                1635

 Asp Phe Asp Pro Ala Pro Val Lys Ser Lys Phe Asp Ser Leu Asp
                1640                1645                1650

 Phe Asp Thr Leu Leu Lys Gln Ala Gln Lys Asn Leu Arg Arg
                1655                1660

<210> 974
<211> 2448
<212> DNA
<213> Homo sapien

<400> 974
 cagagtttga aaaaacggat ggaagtacca gactatgaaa tgttcccagc 50

 aagttcttca tctccatctg agaccacctc agcctggatt tcattgtcca 100

 tgtcattatc agcattttgg tccaagccat tcaacaagtc tctaggaagt 150

 tccaaactgt ccaacatttc cctgccttct tctgagccct ccaaactgtt 200

 ccaacctctg ccagttccaa agttgcttcc acattttcag gttcaccagg 250

 ctggtttaac ctgcgattat tcagaacttc ctcaccatat cagcacagaa 300

 caagaaatag agtgtcttat tcaatctgtg cattatttgc tgaaaaattt 350

 accaaatcct actcttgtga caattgcaag gtcaagtctg gatgattact 400

 gtccttctga ccaagttgac actattcaag aaaaggtcct caatatgcta 450

 cgtgccctct atggaaatct agacctccaa gtgtatgcag cagagtctcc 500

 tccatcttga aacaaacaaa acattaggct cctgttgtat cttggtttag 550

 taacaggccc ttaattaact tatttgtaca tgagtcttcc agagaacact 600

 gttttatatt aactttcagt tgaaatcttt cagatatttt gaatctctga 650

 acaaccattg tcagttgtga atgatggtaa attttttggc atcaagtctc 700

 ataaccccaa ctgatagaac tgttgcttat ctgtcttcct taagtatttt 750

 ttagggtttt gttttttttt tttgtttgtt tgtttgtttg tcttcacttt 800

 tcccccaggt ctgttgagct gtatgagatt cattcatact tcatttattc 850

 attcaactaa tatttgttga acacttacat gtaccagaca ttattaagtg 900

 ctgggtatat ggtaatgaac agaatagaca aggcccctgc ccttttaggg 950

 gagacagatg agaagtaaat tacgggttat gagaaatgtt atgaaggaaa 1000

 ggacaacaac agacatgtct tagtacttag ggtatcatgg ctttatagga 1050

 aagtaacatt ctctatcttt tttttttttt ttaattttat aaaaatagag 1100

 atggggtctc accatgttac ccaggctggt ctcaaactcc tgggcacaag 1150

 caatccacct gccttcgcct cccgaagtgc tgggattaca gatgtaagtc 1200

 actaccccag ccagaaacta acattctcaa aagctactac caaaaaaacc 1250

 ccacaaattt gccaatccat gaaagtatca taggaagtct acctttccaa 1300

 ggaatttggc attgtggccc tgctcttgcc aaatgctctc cagcattgtt 1350

 ggtatcaagg tggtctggtt gagtaaactt gaccaaacaa aaattaactg 1400

 ttttttgctt ttctgttttt gttttgctga tcaaaaaagc ccttcagggt 1450

 cttttgtgca tccaggaggt cattgtagat atcaataata tagtgcctaa 1500

 gtgccacttt attgccaagt ctagattgat acttttttca gataaaccag 1550

 ctttttatgt aaagagtaag ggaaaaagtt aaatctttaa ttctgacctg 1600

 ccataaatac ccaaagatat aacctgtctt ccaccacccc cctcataact 1650

 aagacatcct tcctgagtca ctcttaatca tgaaacttga ttttctcaat 1700

 tggccagtct tctgatcttt agtatctctt tagttcagta atttttacct 1750

 acctacttga tttattttcc tttaaaaggt gaaatgacat ttaaagaaaa 1800

 acaaacaccc atcattcctc agtcccaaca cagcagttct tttcactctt 1850

 gcttgtaact ttcaggcctt acccacatgt gttcctatag agttgcatgt 1900

 agctaaaatt atagtgtgct gcctaacttt gtgctaataa cgaaggacac 1950

 acattatcat tgcctcacag tggatggcac ctgaccccat ttttccaagg 2000

 attctatttt ccagtgaatt tttgtcaccg agttaatttc ccaagtctga 2050

 tagcatgaat gcttatttgt gctgtgaaaa gcagagcagc ctgactcagc 2100

 tttccatttt cataggataa tatgtgccaa aaaaggttta ttttcttggt 2150

 aaaatcagga ttgtagaatt gtgctatttt taatttttaa aatttttggt 2200

 tagagcttat agacattact tttatgatta ttttgcgtgc taaataagtt 2250

 aaagggtatg ttttgaacta tagcactaat taatgtgtgt gatcctagta 2300

 tgttgatagc tttgattttg tgagtggttt actagtcatt tattatgatt 2350

 cccatgaact ctgatatgat tcattgtggt tttaactcag gttgaataaa 2400

 agcatccatt tcttttaaaa aaaaaaaaaa gaaaaaaaaa aaaaaaaa 2448

<210> 975
<211> 5632
<212> DNA
<213> Homo sapien

<400> 975
 gacaaagaga actaatgctt tgtgctgatt catatttgaa tcgaggcatt 50

 gggaaccctg tatgccttgt ttgtggaaag aaccagtgac accatcactg 100

 agcttcctaa aagttcgaag aagttagagg actatacact ttcttttgaa 150

 cttttataat aaatatttgc tctggttttt ggaacccagg gctgttagag 200

 gggtgagtga caagtcttac aagtggcctt attccaactc cagaaattgc 250

 ccaacggaac tttgagatta tatgcaatcg aaagtgacag gaaacatgcc 300

 aactcaatcc ctcttaatgt acatggatgg gccagaagtg attggcagct 350

 ctcttggcag tccgatggag atggaggatg ccttgtcaat gaaagggacc 400

 gctgttgttc cattccgagc tacacaagaa aaaaatgtca tccaaatcga 450

 ggggtatatg cccttggatt gcatgttctg cagccagacc ttcacacatt 500

 cagaagacct taataaacat gtcttaatgc aacaccggcc taccctctgt 550

 gaaccagcag ttcttcgggt tgaagcagag tatctcagtc cgcttgataa 600

 aagtcaagtg cgaacagaac ctcccaagga aaagaattgc aaggaaaatg 650

 aatttagctg tgaggtatgt gggcagacat ttagagtcgc ttttgatgtt 700

 gagatccaca tgagaacaca caaagattct ttcacttacg ggtgtaacat 750

 gtgcggaaga agattcaagg agccttggtt tcttaaaaat cacatgcgga 800

 cacataatgg caaatcgggg gccagaagca aactgcagca aggcttggag 850

 agtagtccag caacgatcaa cgaggtcgtc caggtgcacg cggccgagag 900

 catctcctct ccttacaaaa tctgcatggt ttgtggcttc ctatttccaa 950

 ataaagaaag tctaattgag caccgcaagg tgcacaccaa aaaaactgct 1000

 ttcggtacca gcagcgcgca gacagactct ccacaaggag gaatgccgtc 1050

 ctcgagggag gacttcctgc agttgttcaa cttgagacca aaatctcacc 1100

 ctgaaacggg gaagaagcct gtcagatgca tccctcagct cgatccgttc 1150

 accaccttcc aggcttggca gctggctacc aaaggaaaag ttgccatttg 1200

 ccaagaagtg aaggaatcgg ggcaagaagg gagcaccgac aacgacgatt 1250

 cgagttccga gaaggagctt ggagaaacaa ataagggcag ttgtgcaggc 1300

 ctctcgcaag agaaagagaa gtgcaaacac tcccacggcg aagcgccctc 1350

 cgtggacgcg gatcccaagt tacccagtag caaggagaag cccactcact 1400

 gctccgagtg cggcaaagct ttcagaacct accaccagct ggtcttgcac 1450

 tccagggtcc acaagaagga ccggagggcc ggcgcggagt cgcccaccat 1500

 gtctgtggac gggaggcagc cggggacgtg ttctcctgac ctcgccgccc 1550

 ctctggatga aaatggagcc gtggatcgag gggaaggtgg ttctgaagac 1600

 ggatctgagg atgggcttcc cgaaggaatc catctggata aaaatgatga 1650

 tggaggaaaa ataaaacatc ttacatcttc aagagagtgt agttattgtg 1700

 gaaagttttt ccgttcaaat tattacctca atattcatct cagaacgcat 1750

 acaggtgaaa aaccatacaa atgtgaattt tgtgaatatg ctgcagccca 1800

 gaagacatct ctgaggtatc acttggagag acatcacaag gaaaaacaaa 1850

 ccgatgttgc tgctgaagtc aagaacgatg gtaaaaatca ggacactgaa 1900

 gatgcactat taaccgctga cagtgcgcaa accaaaaatt tgaaaagatt 1950

 ttttgatggt gccaaagatg ttacaggcag tccacctgca aagcagctta 2000

 aggagatgcc ttctgttttt cagaatgttc tgggcagcgc tgtcctctca 2050

 ccagcacaca aagatactca ggatttccat aaaaatgcag ctgatgacag 2100

 tgctgataaa gtgaataaaa accctacccc tgcttacctg gacctgttaa 2150

 aaaagagatc agcagttgaa actcaggcaa ataacctcat ctgtagaacc 2200

 aaggcggatg ttactcctcc tccggatggc agtaccaccc ataaccttga 2250

 agttagcccc aaagagaagc aaacggagac cgcagctgac tgcagataca 2300

 ggccaagtgt ggattgtcac gaaaaacctt taaatttatc cgtgggggct 2350

 cttcacaatt gcccggcaat ttctttgagt aaaagtttga ttccaagtat 2400

 cacctgtcca ttttgtacct tcaagacatt ttatccagaa gttttaatga 2450

 tgcaccagag actggagcat aaatacaatc ctgacgttca taaaaactgt 2500

 cgaaacaagt ccttgcttag aagtcgacgt accggatgcc cgccagcgtt 2550

 gctgggaaaa gatgtgcctc ccctctctag tttctgtaaa cccaagccca 2600

 agtctgcttt cccggcgcag tccaaatccc tgccatctgc gaaggggaag 2650

 cagagccctc ctgggccagg caaggcccct ctgacttcag ggatagactc 2700

 tagcacttta gccccaagta acctgaagtc ccacagacca cagcagaatg 2750

 tgggggtcca aggggccgcc accaggcaac agcaatctga gatgtttcct 2800

 aaaaccagtg tttcccctgc accggataag acaaaaagac ccgagacaaa 2850

 attgaaacct cttccagtag ctccttctca gcccaccctc ggcagcagta 2900

 acatcaatgg ttccatcgac taccccgcca agaacgacag cccgtgggca 2950

 cctccgggaa gagactattt ctgtaatcgg agtgccagca atactgcagc 3000

 agaatttggt gagccccttc caaaaagact gaagtccagc gtggttgccc 3050

 ttgacgttga ccagcccggg gccaattaca gaagaggcta tgaccttccc 3100

 aagtaccata tggtcagagg catcacatca ctgttaccgc aggactgtgt 3150

 gtatccgtcg caggcgctgc ctcccaaacc aaggttcctg agctccagcg 3200

 aggtcgattc tccaaatgtg ctgactgttc agaagcccta tggtggctcc 3250

 gggccacttt acacttgtgt gcctgctggt agtccagcat ccagctcgac 3300

 gttagaagga aaaaggcctg tgtcatatca acacttatct aacagcatgg 3350

 cacaaaagag aaactatgag aattttattg ggaatgcaca ttatcgacca 3400

 aatgacaaaa aaacttgatt cactaattag ggggaaaaaa ggtcttggtg 3450

 gatgtcagtg cttactcccc atgaaattaa attttacttc atcctttgag 3500

 aagcgaatgg tgaaagctac tgaaataagc tgtgattgta ctgtacataa 3550

 aacatatgag gaatctgcaa ggaacactac agttgtgtaa agttgttctg 3600

 ttaacttttg taccaaatag caatacaaac tagttggaac agttggaact 3650

 tacatacatg gggactggaa atctctattt tgtccctgaa taatattttt 3700

 cttagaattg accaaataag aagtggaatt tttgcatact tgagcgctgc 3750

 tgaaaagaaa tcatttgggt tgggtggggc gggatggggg aaaagtatat 3800

 aatgcttgca cctcaggtaa aaatctgtaa atatctaagt tgtaaacctg 3850

 cttgttcaaa tactgtgtgt attccttttc tctaatgcag ctcatcactt 3900

 ggagcagttt ctgctattgt gctctttcat ttaaaatgta tgtttttttt 3950

 tttttaaact gtcaatgatt ttgtattatg ttgaatccac ccaaatctat 4000

 tgttgtctta aaattgttaa tggaagtatt gaccctctat gatatgtgct 4050

 gcagatatcg aggtcagcca ttcggaagct ggcagcattt tatcgcaact 4100

 ttgagcatct cagatgggga aggcaccttc ttcctcgcct ctccagattg 4150

 tcctggaacc tccaggatcc ttgactgagg gcgttgggat ggcttgtagg 4200

 atttttaaga gagtgtgtct acagacaagc attttctctg tagagcagcc 4250

 acacgttgta taaacataaa ctgtatgtgc agttatttaa atttgtttct 4300

 gtcaaattaa tcatttttgt tggacgattc agtggcgggg gggttttgcc 4350

 taaattagta tataaaaaca aaaatgctaa attatatctg tgaattgcag 4400

 gtattgggga acagttttaa gggaaatttt ggggggaaca ttttaggttt 4450

 gtatttggta gtcttaatgt atctggcatt tgggtgaact gtggacatac 4500

 tagagttgat tatagacaca ttgattttga ataaggaact gctggccgag 4550

 cccgctggga gtctagaaag agaaaatctg tttctagacc tcagttattt 4600

 tcccattttt ggttgttttg aagcagtaac atttttctca gtgcacatgc 4650

 aatttgggtt ttagagaaga tggccaccag ctggcttcct agatatttta 4700

 aacttttgtt ctttaatatg ctgtccatgg ctgagtttat tagtacatgg 4750

 gcttagtgac cacaaaatat tttattaaga aactgtttca aaaataaatt 4800

 tgcactgttc atttttctgg cctcgctgtt ctccatagag caagggtaat 4850

 cctagaaaaa attttttttt tttaaattat gcaacgtaag atgtcctcct 4900

 tgatagaagt cttagctcct gtgttacaag ggagaactca tttgagatca 4950

 gtctgttggc attgcaatga agtgctttgt atcaggaaag tgtacactat 5000

 tgaccttttt tcctgttcac aagctgagcc atatgtacat aatctagatt 5050

 ttgttttcat agttttgcac ttttatagcc tatttttgaa gattaacaca 5100

 tttgcaagat gattgactca atctttgcct aatccaatga gtgttacaga 5150

 gagcttgctg tgactagaac cataaatctt aaagggggta tgtgataata 5200

 gagggctgga atttaaacct gtatttaaaa aaaagaatca ccaaatctat 5250

 ttgaaaacaa gtcgatttgt attatgctgg aattttttgg gctttcagat 5300

 ttctcttttt aaccacattt ctgaatgtat aaaaatacca attattttcc 5350

 tacagccctt tgtacttcaa aatatgtttt tgtgtccatc agtattaact 5400

 attggtatac tactggtttt atattttttt ttctttgaga caacagtaca 5450

 tataatagag gtacaattcg ttggattttt gtttatgtat ttatttcatt 5500

 ccagtttgat ttattttaat tgttgatact taagttgtca aacagtagac 5550

 attacgtgtt ttatttatga tatatttcag cttaaagtta tgttattata 5600

 tgtggaagtg taaatataga tttggtgttt tg 5632

<210> 976
<211> 1048
<212> PRT
<213> Homo sapien

<400> 976
 Met Gln Ser Lys Val Thr Gly Asn Met Pro Thr Gln Ser Leu Leu
   1               5                  10                  15

 Met Tyr Met Asp Gly Pro Glu Val Ile Gly Ser Ser Leu Gly Ser
                  20                  25                  30

 Pro Met Glu Met Glu Asp Ala Leu Ser Met Lys Gly Thr Ala Val
                  35                  40                  45

 Val Pro Phe Arg Ala Thr Gln Glu Lys Asn Val Ile Gln Ile Glu
                  50                  55                  60

 Gly Tyr Met Pro Leu Asp Cys Met Phe Cys Ser Gln Thr Phe Thr
                  65                  70                  75

 His Ser Glu Asp Leu Asn Lys His Val Leu Met Gln His Arg Pro
                  80                  85                  90

 Thr Leu Cys Glu Pro Ala Val Leu Arg Val Glu Ala Glu Tyr Leu
                  95                 100                 105

 Ser Pro Leu Asp Lys Ser Gln Val Arg Thr Glu Pro Pro Lys Glu
                 110                 115                 120

 Lys Asn Cys Lys Glu Asn Glu Phe Ser Cys Glu Val Cys Gly Gln
                 125                 130                 135

 Thr Phe Arg Val Ala Phe Asp Val Glu Ile His Met Arg Thr His
                 140                 145                 150

 Lys Asp Ser Phe Thr Tyr Gly Cys Asn Met Cys Gly Arg Arg Phe
                 155                 160                 165

 Lys Glu Pro Trp Phe Leu Lys Asn His Met Arg Thr His Asn Gly
                 170                 175                 180

 Lys Ser Gly Ala Arg Ser Lys Leu Gln Gln Gly Leu Glu Ser Ser
                 185                 190                 195

 Pro Ala Thr Ile Asn Glu Val Val Gln Val His Ala Ala Glu Ser
                 200                 205                 210

 Ile Ser Ser Pro Tyr Lys Ile Cys Met Val Cys Gly Phe Leu Phe
                 215                 220                 225

 Pro Asn Lys Glu Ser Leu Ile Glu His Arg Lys Val His Thr Lys
                 230                 235                 240

 Lys Thr Ala Phe Gly Thr Ser Ser Ala Gln Thr Asp Ser Pro Gln
                 245                 250                 255

 Gly Gly Met Pro Ser Ser Arg Glu Asp Phe Leu Gln Leu Phe Asn
                 260                 265                 270

 Leu Arg Pro Lys Ser His Pro Glu Thr Gly Lys Lys Pro Val Arg
                 275                 280                 285

 Cys Ile Pro Gln Leu Asp Pro Phe Thr Thr Phe Gln Ala Trp Gln
                 290                 295                 300

 Leu Ala Thr Lys Gly Lys Val Ala Ile Cys Gln Glu Val Lys Glu
                 305                 310                 315

 Ser Gly Gln Glu Gly Ser Thr Asp Asn Asp Asp Ser Ser Ser Glu
                 320                 325                 330

 Lys Glu Leu Gly Glu Thr Asn Lys Gly Ser Cys Ala Gly Leu Ser
                 335                 340                 345

 Gln Glu Lys Glu Lys Cys Lys His Ser His Gly Glu Ala Pro Ser
                 350                 355                 360

 Val Asp Ala Asp Pro Lys Leu Pro Ser Ser Lys Glu Lys Pro Thr
                 365                 370                 375

 His Cys Ser Glu Cys Gly Lys Ala Phe Arg Thr Tyr His Gln Leu
                 380                 385                 390

 Val Leu His Ser Arg Val His Lys Lys Asp Arg Arg Ala Gly Ala
                 395                 400                 405

 Glu Ser Pro Thr Met Ser Val Asp Gly Arg Gln Pro Gly Thr Cys
                 410                 415                 420

 Ser Pro Asp Leu Ala Ala Pro Leu Asp Glu Asn Gly Ala Val Asp
                 425                 430                 435

 Arg Gly Glu Gly Gly Ser Glu Asp Gly Ser Glu Asp Gly Leu Pro
                 440                 445                 450

 Glu Gly Ile His Leu Asp Lys Asn Asp Asp Gly Gly Lys Ile Lys
                 455                 460                 465

 His Leu Thr Ser Ser Arg Glu Cys Ser Tyr Cys Gly Lys Phe Phe
                 470                 475                 480

 Arg Ser Asn Tyr Tyr Leu Asn Ile His Leu Arg Thr His Thr Gly
                 485                 490                 495

 Glu Lys Pro Tyr Lys Cys Glu Phe Cys Glu Tyr Ala Ala Ala Gln
                 500                 505                 510

 Lys Thr Ser Leu Arg Tyr His Leu Glu Arg His His Lys Glu Lys
                 515                 520                 525

 Gln Thr Asp Val Ala Ala Glu Val Lys Asn Asp Gly Lys Asn Gln
                 530                 535                 540

 Asp Thr Glu Asp Ala Leu Leu Thr Ala Asp Ser Ala Gln Thr Lys
                 545                 550                 555

 Asn Leu Lys Arg Phe Phe Asp Gly Ala Lys Asp Val Thr Gly Ser
                 560                 565                 570

 Pro Pro Ala Lys Gln Leu Lys Glu Met Pro Ser Val Phe Gln Asn
                 575                 580                 585

 Val Leu Gly Ser Ala Val Leu Ser Pro Ala His Lys Asp Thr Gln
                 590                 595                 600

 Asp Phe His Lys Asn Ala Ala Asp Asp Ser Ala Asp Lys Val Asn
                 605                 610                 615

 Lys Asn Pro Thr Pro Ala Tyr Leu Asp Leu Leu Lys Lys Arg Ser
                 620                 625                 630

 Ala Val Glu Thr Gln Ala Asn Asn Leu Ile Cys Arg Thr Lys Ala
                 635                 640                 645

 Asp Val Thr Pro Pro Pro Asp Gly Ser Thr Thr His Asn Leu Glu
                 650                 655                 660

 Val Ser Pro Lys Glu Lys Gln Thr Glu Thr Ala Ala Asp Cys Arg
                 665                 670                 675

 Tyr Arg Pro Ser Val Asp Cys His Glu Lys Pro Leu Asn Leu Ser
                 680                 685                 690

 Val Gly Ala Leu His Asn Cys Pro Ala Ile Ser Leu Ser Lys Ser
                 695                 700                 705

 Leu Ile Pro Ser Ile Thr Cys Pro Phe Cys Thr Phe Lys Thr Phe
                 710                 715                 720

 Tyr Pro Glu Val Leu Met Met His Gln Arg Leu Glu His Lys Tyr
                 725                 730                 735

 Asn Pro Asp Val His Lys Asn Cys Arg Asn Lys Ser Leu Leu Arg
                 740                 745                 750

 Ser Arg Arg Thr Gly Cys Pro Pro Ala Leu Leu Gly Lys Asp Val
                 755                 760                 765

 Pro Pro Leu Ser Ser Phe Cys Lys Pro Lys Pro Lys Ser Ala Phe
                 770                 775                 780

 Pro Ala Gln Ser Lys Ser Leu Pro Ser Ala Lys Gly Lys Gln Ser
                 785                 790                 795

 Pro Pro Gly Pro Gly Lys Ala Pro Leu Thr Ser Gly Ile Asp Ser
                 800                 805                 810

 Ser Thr Leu Ala Pro Ser Asn Leu Lys Ser His Arg Pro Gln Gln
                 815                 820                 825

 Asn Val Gly Val Gln Gly Ala Ala Thr Arg Gln Gln Gln Ser Glu
                 830                 835                 840

 Met Phe Pro Lys Thr Ser Val Ser Pro Ala Pro Asp Lys Thr Lys
                 845                 850                 855

 Arg Pro Glu Thr Lys Leu Lys Pro Leu Pro Val Ala Pro Ser Gln
                 860                 865                 870

 Pro Thr Leu Gly Ser Ser Asn Ile Asn Gly Ser Ile Asp Tyr Pro
                 875                 880                 885

 Ala Lys Asn Asp Ser Pro Trp Ala Pro Pro Gly Arg Asp Tyr Phe
                 890                 895                 900

 Cys Asn Arg Ser Ala Ser Asn Thr Ala Ala Glu Phe Gly Glu Pro
                 905                 910                 915

 Leu Pro Lys Arg Leu Lys Ser Ser Val Val Ala Leu Asp Val Asp
                 920                 925                 930

 Gln Pro Gly Ala Asn Tyr Arg Arg Gly Tyr Asp Leu Pro Lys Tyr
                 935                 940                 945

 His Met Val Arg Gly Ile Thr Ser Leu Leu Pro Gln Asp Cys Val
                 950                 955                 960

 Tyr Pro Ser Gln Ala Leu Pro Pro Lys Pro Arg Phe Leu Ser Ser
                 965                 970                 975

 Ser Glu Val Asp Ser Pro Asn Val Leu Thr Val Gln Lys Pro Tyr
                 980                 985                 990

 Gly Gly Ser Gly Pro Leu Tyr Thr Cys Val Pro Ala Gly Ser Pro
                 995                1000                1005

 Ala Ser Ser Ser Thr Leu Glu Gly Lys Arg Pro Val Ser Tyr Gln
                1010                1015                1020

 His Leu Ser Asn Ser Met Ala Gln Lys Arg Asn Tyr Glu Asn Phe
                1025                1030                1035

 Ile Gly Asn Ala His Tyr Arg Pro Asn Asp Lys Lys Thr
                1040                1045

<210> 977
<211> 6196
<212> DNA
<213> Homo sapien

<400> 977
 tgaggaactg cgtgtggagt cagcccagtc tggatgcaca ggaggatgct 50

 ggcggcacag tgagtgaggc ctggtgccag agctgtgcgg accccttgtt 100

 ggccatggag cagcaggccc agaggccctc tccccagccc tgcttgcctg 150

 cctcggagag gacagaggcc taggcccacg ggggagggtg ttggcagaca 200

 gatgccctcc aggccctggg gcctccttaa cggcccctta acgacacgcg 250

 tgccaagggt ggaggatgcc agccaagggg cgctacttcc tcaacgaggg 300

 cgaggagggc cctgaccaag atgcgctcta cgagaagtac cagctcacca 350

 gccagcatgg gccgctgctg ctcacgctcc tgctggtggc cgccactgcc 400

 tgcgtggccc tcatcatcat tgccttcagc cagggggacc cctccagaca 450

 ccaggccatt ctgggcatgg cgttcctggt gctggcggtg tttgcggccc 500

 tctctgtgct gatgtacgtc gagtgtctcc tgcggcgctg gctcagggcc 550

 ttggcgctgc tcacctgggc ctgcttggtg gcgctgggct atgtgctggt 600

 gttcgacgca tggacaaagg cggcctgtgc gtgggagcag gtgcccttct 650

 tcctgttcat tgtcttcgtg gtgtacacac tactgccctt cagcatgcgg 700

 ggcgctgtcg ccgttggggc cgtctccact gcctcccacc tcctggtgct 750

 cggttctttg atgggaggct tcacgacacc cagtgtccgg gtggggctgc 800

 agctgctggc caacgcagtc atcttcctgt gtgggaacct gacaggcgcc 850

 ttccacaagc accaaatgca ggatgcgtcc cgggacctct tcacctacac 900

 tgtgaagtgc atccagatcc gccggaagct gcgcatcgag aagcgccagc 950

 aggagaacct gctgctgtca gtgcttccgg cccacatctc catgggcatg 1000

 aagctggcca tcatcgaacg gctcaaggag catggtgacc gtcgctgcat 1050

 gcctgacaac aacttccaca gcctctacgt caagaggcac cagaatgtca 1100

 gcatcctcta tgcggacatc gtgggcttca cgcagctggc cagcgactgt 1150

 tctcccaagg agctggtggt ggtgctgaat gagctctttg gcaagttcga 1200

 ccagatcgcc aaggccaacg agtgcatgcg aatcaagatc ctcggcgact 1250

 gctactactg tgtatcgggc ctgcccgtgt cgctgcctac ccacgcccgg 1300

 aactgcgtga agatggggct ggacatgtgc caggccatca agcaggtgcg 1350

 ggaggccacg ggcgtggaca tcaacatgcg tgtgggcata cactcgggga 1400

 atgtgctgtg cggggtcatc gggctgcgca agtggcagta tgacgtgtgg 1450

 tcccacgacg tgtccctggc caaccggatg gaggcagccg gagtacccgg 1500

 ccgggtgcac atcacggagg ccacgctaaa gcacctggac aaggcgtacg 1550

 aggtggagga tgggcacggg cagcagcggg acccctacct caaggagatg 1600

 aacatccgca cctacctggt catcgacccc cggagccagc agccaccccc 1650

 gcccagccaa cacctcccca ggcccaaggg ggacgcggcc ctgaagatgc 1700

 gggcgtcagt gcgcatgacc cggtacctcg agtcctgggg ggcggcacgg 1750

 ccctttgcac atctcaacca ccgtgagagc gtgagcagtg gtgagaccca 1800

 cgtccccaac gggcggaggc ctaagagcgt tccccagcgc caccgccgga 1850

 ccccagacag aagcatgtcc cccaaggggc ggtcggagga tgactcgtac 1900

 gatgacgaga tgctgtcagc cattgagggg ctcagctcca cgaggccctg 1950

 ctgctccaag tccgatgact tctacacctt tgggtccatc ttcctggaga 2000

 agggctttga gcgcgagtac cgcctggcac ccatcccccg ggcccgccac 2050

 gactttgcct gcgccagcct gatcttcgtc tgcatcctgc tcgtccatgt 2100

 cctgctcatg cccaggacgg cggcactggg tgtgtccttc gggctggtgg 2150

 cctgtgtact ggggctggtg ctgggcctgt gctttgccac caagttctcg 2200

 aggtgctgcc cagctcgggg gacgctctgc actatctctg agagggtgga 2250

 gacacagccc ctgctgaggc tgaccctggc cgtcctgacc atcggcagcc 2300

 tgctcactgt ggccatcatc aacctgcccc tgatgccttt ccaagttcca 2350

 gagctgcctg ttggcaatga gacaggccta ctggccgcga gcagcaagac 2400

 aagagccctg tgtgagcccc tcccgtacta cacctgcagc tgtgtcctgg 2450

 gcttcatcgc ctgctcggtc ttcctgagga tgagcctgga gccaaaggtt 2500

 gtgctgctga cagtggccct ggtggcctac ctggtgctct tcaacctctc 2550

 cccatgctgg cagtgggact gctgcggcca aggcctgggc aacctcacca 2600

 agcccaacgg caccaccagt ggcaccccta gctgttcctg gaaggacctg 2650

 aagaccatga ccaatttcta cctggtcctg ttctacatca ccctgcttac 2700

 actctccaga cagattgact attactgccg cttggactgc ctatggaaga 2750

 agaagttcaa gaaggagcac gaggagtttg agaccatgga gaacgtgaac 2800

 cgccttcttc tggagaacgt cctgccagcc cacgtggctg cccactttat 2850

 cggtgacaag ttaaacgagg actggtacca tcagtcctat gactgcgtct 2900

 gtgtcatgtt tgcctccgtg ccggacttca aagtgttcta cacagagtgc 2950

 gatgtcaaca aagaagggct ggagtgccta cgcctgctca atgagatcat 3000

 tgccgacttc gacgagctcc tactgaagcc caagttcagc ggcgtggaga 3050

 agatcaagac catcggcagc acgtacatgg cagctgcagg gctcagcgtc 3100

 gcctcagggc acgagaacca ggagctggag cggcagcatg cccacattgg 3150

 tgtcatggtg gagttcagca tcgccctgat gagtaagctg gacggcatca 3200

 acaggcactc cttcaactcc ttccgcctcc gcgtcggcat aaaccatggg 3250

 cctgtgattg ctggagtgat tggggcccga aaacctcagt atgacatctg 3300

 gggaaacact gtcaatgtgg ccagccgaat ggaaagcact ggagaacttg 3350

 ggaaaatcca ggttaccgag gagacctgca ccatcctcca gggcctcggg 3400

 tactcttgtg aatgccgtgg cctgatcaac gtcaaaggca aaggcgagct 3450

 gaggacttac tttgtctgta cggacactgc caagtttcag gggctggggc 3500

 tgaactgagg gctcctgctg gattccgaaa aggccgggaa gccagtctcc 3550

 ttccctgaag caagcccagg agaagactct ccgccccacg ccaatcccaa 3600

 aggcatgcag atggctgtgc atgttggctt ctttggacct gcactggagg 3650

 atttctcaga cacatgcacc agattctggc tcgaagcagc cactgagcca 3700

 taatgcgcag gggaggccag aagctctgtg cctggtctgt aacagtttcc 3750

 aggccagctg gagaatgttc actggttcgg ggctgacttt gagatctttg 3800

 ttccctgagg tgccaggcag gcaactttag cacatgatga aaacagactt 3850

 ccacctcagt ggcctgtggg cacgcacaag tgaggtctgt ttttctagac 3900

 accaaggggg agtaagctga gctgtctagc acggattgga gactccctct 3950

 ccctggtggg cctggcaatg acagcatttc tcacagaggc attctggtaa 4000

 atgaagctga aaggggtgtt ttacatctgt aaacggtttc aaacaggtag 4050

 agagaaaaac accacaatta acactgttac tttttgcctt gtctggcatg 4100

 tttgttttaa atgaatacat taatggggtt tttatccttt tgaatgactt 4150

 ttcagacact agacataaat ctcttccctc cagtgtatgc tctgcctttt 4200

 taaccactga catgtaagga ggactactgt ctagcatcag cttatggggt 4250

 cagctggctg tggggataga gtcctgagga atgtggtcac agcaagaagg 4300

 cggggagcag cagagccttg cctttgaatg aggcagcttg tgaggcaagc 4350

 attctggaga gaggtgcttt gaaagtaagg tgcggccttt cacctcttcc 4400

 ttgattactc acacatcttt gcgttctccc ctgccgtcct tcaactgtat 4450

 cttacttttc ttaccagaaa ggaatggagt ctgtttagag acaacttgga 4500

 caacctgtga gtgcatctct tctttccttt agtcttcaca gctaactctg 4550

 gagagcttca aaactagaag gatctactcc gcatgggtgc atgcagaggc 4600

 tcctggatct gggaagcccg ccccctcaca aatgctgagc cgttcttgct 4650

 ctgaaactgc gtgagtcaag gcaaatgcaa aaagccaggt tttggggatg 4700

 tgtcttactg tgcttcaact tcccaaggaa ttgaaagtca acctaactgt 4750

 aacaacaggg tgagaaatga ccaaactgcc cgtgactttt tctgaatgga 4800

 cttcataacc ggaagactta accggtggcc tcatcaccag agcatcgcca 4850

 ggatttctaa tgcactcagt ttccctacat agcagggatt cttagctagg 4900

 tgtccccatg aaccccgtaa agttctacac aaagtcttgc atacaggagc 4950

 ctttacaaga tgattataca gggttgcaga ttgggtgact gaccagactt 5000

 gttggggtcc tgggatgagt tgccccgggc tgcaaattaa gagtacagct 5050

 aagtgcgggg gtggcggtgg agggaacgaa aattgaacct gtctgcctgt 5100

 gctgtgtcgt gtggctttat cagcccgagg aagggcaggt gtattctaat 5150

 ttgcacaaag gtgctgggta gactagtggc agctctcatg tgctgcacat 5200

 aagtggaatc agtatgaata gaagaacttg ctgtataaag gaatttcatg 5250

 gcaacaatgc tggtaagggc aattagcctc gcttaagttg ccttttttac 5300

 acaccaaaac tttttacatg aagggctggt ttcacatgaa tactatactg 5350

 aaatctgtgc cacaccaaaa ctttttacat gaagggctgg tttcacatga 5400

 atactatact gaaatctgtg ctctcaagat ctagcagtga ccagggctgc 5450

 ccggcggggg ctctcctggc aagtcaggaa ggtttctgtt gctaatataa 5500

 catagaaaca cattagtgca ctgggcctct ctgaggtcag catatttgta 5550

 ctcttggaat atttgttttt ttcttcagta acaacagaaa ccccagttgg 5600

 gagtttaaca aataactgac taccactcac tcatgcattt ttatttccaa 5650

 ttaaagcaaa gcactgtgct gtgctcagat aataatagtt tgtaagtaaa 5700

 agtttttagt tttcagtgtt caggttatag aatataactg accataaaaa 5750

 ttacctgcag gtattttctt tttatgaact tgtttttaaa ttaccaagta 5800

 attactggtg tcattttgtt ttatgacaga cacacgtatc taacaaacaa 5850

 acaaacagtg accttctcca tgggtcaagg acttccttac aatttctcct 5900

 gagttaactt ttgtgaaaat aatacctaag gttttctggc ttattgagga 5950

 aatttcctaa caaacaaaca aacaaacaaa cagaagagaa gatcattaac 6000

 cactgtatac tttgtgtata taataggtca gtgtaaagaa atatgatttg 6050

 aggtggtgca tgcaagtaac tagggtttat tctatataat gaatatttat 6100

 agatctgtaa catttgtttc aaaatgctgt ttcattttta taaagtacca 6150

 gtgtttagct gctttttata cattaaatta gcaatttgaa aaactc 6196

<210> 978
<211> 1080
<212> PRT
<213> Homo sapien

<400> 978
 Met Pro Ala Lys Gly Arg Tyr Phe Leu Asn Glu Gly Glu Glu Gly
   1               5                  10                  15

 Pro Asp Gln Asp Ala Leu Tyr Glu Lys Tyr Gln Leu Thr Ser Gln
                  20                  25                  30

 His Gly Pro Leu Leu Leu Thr Leu Leu Leu Val Ala Ala Thr Ala
                  35                  40                  45

 Cys Val Ala Leu Ile Ile Ile Ala Phe Ser Gln Gly Asp Pro Ser
                  50                  55                  60

 Arg His Gln Ala Ile Leu Gly Met Ala Phe Leu Val Leu Ala Val
                  65                  70                  75

 Phe Ala Ala Leu Ser Val Leu Met Tyr Val Glu Cys Leu Leu Arg
                  80                  85                  90

 Arg Trp Leu Arg Ala Leu Ala Leu Leu Thr Trp Ala Cys Leu Val
                  95                 100                 105

 Ala Leu Gly Tyr Val Leu Val Phe Asp Ala Trp Thr Lys Ala Ala
                 110                 115                 120

 Cys Ala Trp Glu Gln Val Pro Phe Phe Leu Phe Ile Val Phe Val
                 125                 130                 135

 Val Tyr Thr Leu Leu Pro Phe Ser Met Arg Gly Ala Val Ala Val
                 140                 145                 150

 Gly Ala Val Ser Thr Ala Ser His Leu Leu Val Leu Gly Ser Leu
                 155                 160                 165

 Met Gly Gly Phe Thr Thr Pro Ser Val Arg Val Gly Leu Gln Leu
                 170                 175                 180

 Leu Ala Asn Ala Val Ile Phe Leu Cys Gly Asn Leu Thr Gly Ala
                 185                 190                 195

 Phe His Lys His Gln Met Gln Asp Ala Ser Arg Asp Leu Phe Thr
                 200                 205                 210

 Tyr Thr Val Lys Cys Ile Gln Ile Arg Arg Lys Leu Arg Ile Glu
                 215                 220                 225

 Lys Arg Gln Gln Glu Asn Leu Leu Leu Ser Val Leu Pro Ala His
                 230                 235                 240

 Ile Ser Met Gly Met Lys Leu Ala Ile Ile Glu Arg Leu Lys Glu
                 245                 250                 255

 His Gly Asp Arg Arg Cys Met Pro Asp Asn Asn Phe His Ser Leu
                 260                 265                 270

 Tyr Val Lys Arg His Gln Asn Val Ser Ile Leu Tyr Ala Asp Ile
                 275                 280                 285

 Val Gly Phe Thr Gln Leu Ala Ser Asp Cys Ser Pro Lys Glu Leu
                 290                 295                 300

 Val Val Val Leu Asn Glu Leu Phe Gly Lys Phe Asp Gln Ile Ala
                 305                 310                 315

 Lys Ala Asn Glu Cys Met Arg Ile Lys Ile Leu Gly Asp Cys Tyr
                 320                 325                 330

 Tyr Cys Val Ser Gly Leu Pro Val Ser Leu Pro Thr His Ala Arg
                 335                 340                 345

 Asn Cys Val Lys Met Gly Leu Asp Met Cys Gln Ala Ile Lys Gln
                 350                 355                 360

 Val Arg Glu Ala Thr Gly Val Asp Ile Asn Met Arg Val Gly Ile
                 365                 370                 375

 His Ser Gly Asn Val Leu Cys Gly Val Ile Gly Leu Arg Lys Trp
                 380                 385                 390

 Gln Tyr Asp Val Trp Ser His Asp Val Ser Leu Ala Asn Arg Met
                 395                 400                 405

 Glu Ala Ala Gly Val Pro Gly Arg Val His Ile Thr Glu Ala Thr
                 410                 415                 420

 Leu Lys His Leu Asp Lys Ala Tyr Glu Val Glu Asp Gly His Gly
                 425                 430                 435

 Gln Gln Arg Asp Pro Tyr Leu Lys Glu Met Asn Ile Arg Thr Tyr
                 440                 445                 450

 Leu Val Ile Asp Pro Arg Ser Gln Gln Pro Pro Pro Pro Ser Gln
                 455                 460                 465

 His Leu Pro Arg Pro Lys Gly Asp Ala Ala Leu Lys Met Arg Ala
                 470                 475                 480

 Ser Val Arg Met Thr Arg Tyr Leu Glu Ser Trp Gly Ala Ala Arg
                 485                 490                 495

 Pro Phe Ala His Leu Asn His Arg Glu Ser Val Ser Ser Gly Glu
                 500                 505                 510

 Thr His Val Pro Asn Gly Arg Arg Pro Lys Ser Val Pro Gln Arg
                 515                 520                 525

 His Arg Arg Thr Pro Asp Arg Ser Met Ser Pro Lys Gly Arg Ser
                 530                 535                 540

 Glu Asp Asp Ser Tyr Asp Asp Glu Met Leu Ser Ala Ile Glu Gly
                 545                 550                 555

 Leu Ser Ser Thr Arg Pro Cys Cys Ser Lys Ser Asp Asp Phe Tyr
                 560                 565                 570

 Thr Phe Gly Ser Ile Phe Leu Glu Lys Gly Phe Glu Arg Glu Tyr
                 575                 580                 585

 Arg Leu Ala Pro Ile Pro Arg Ala Arg His Asp Phe Ala Cys Ala
                 590                 595                 600

 Ser Leu Ile Phe Val Cys Ile Leu Leu Val His Val Leu Leu Met
                 605                 610                 615

 Pro Arg Thr Ala Ala Leu Gly Val Ser Phe Gly Leu Val Ala Cys
                 620                 625                 630

 Val Leu Gly Leu Val Leu Gly Leu Cys Phe Ala Thr Lys Phe Ser
                 635                 640                 645

 Arg Cys Cys Pro Ala Arg Gly Thr Leu Cys Thr Ile Ser Glu Arg
                 650                 655                 660

 Val Glu Thr Gln Pro Leu Leu Arg Leu Thr Leu Ala Val Leu Thr
                 665                 670                 675

 Ile Gly Ser Leu Leu Thr Val Ala Ile Ile Asn Leu Pro Leu Met
                 680                 685                 690

 Pro Phe Gln Val Pro Glu Leu Pro Val Gly Asn Glu Thr Gly Leu
                 695                 700                 705

 Leu Ala Ala Ser Ser Lys Thr Arg Ala Leu Cys Glu Pro Leu Pro
                 710                 715                 720

 Tyr Tyr Thr Cys Ser Cys Val Leu Gly Phe Ile Ala Cys Ser Val
                 725                 730                 735

 Phe Leu Arg Met Ser Leu Glu Pro Lys Val Val Leu Leu Thr Val
                 740                 745                 750

 Ala Leu Val Ala Tyr Leu Val Leu Phe Asn Leu Ser Pro Cys Trp
                 755                 760                 765

 Gln Trp Asp Cys Cys Gly Gln Gly Leu Gly Asn Leu Thr Lys Pro
                 770                 775                 780

 Asn Gly Thr Thr Ser Gly Thr Pro Ser Cys Ser Trp Lys Asp Leu
                 785                 790                 795

 Lys Thr Met Thr Asn Phe Tyr Leu Val Leu Phe Tyr Ile Thr Leu
                 800                 805                 810

 Leu Thr Leu Ser Arg Gln Ile Asp Tyr Tyr Cys Arg Leu Asp Cys
                 815                 820                 825

 Leu Trp Lys Lys Lys Phe Lys Lys Glu His Glu Glu Phe Glu Thr
                 830                 835                 840

 Met Glu Asn Val Asn Arg Leu Leu Leu Glu Asn Val Leu Pro Ala
                 845                 850                 855

 His Val Ala Ala His Phe Ile Gly Asp Lys Leu Asn Glu Asp Trp
                 860                 865                 870

 Tyr His Gln Ser Tyr Asp Cys Val Cys Val Met Phe Ala Ser Val
                 875                 880                 885

 Pro Asp Phe Lys Val Phe Tyr Thr Glu Cys Asp Val Asn Lys Glu
                 890                 895                 900

 Gly Leu Glu Cys Leu Arg Leu Leu Asn Glu Ile Ile Ala Asp Phe
                 905                 910                 915

 Asp Glu Leu Leu Leu Lys Pro Lys Phe Ser Gly Val Glu Lys Ile
                 920                 925                 930

 Lys Thr Ile Gly Ser Thr Tyr Met Ala Ala Ala Gly Leu Ser Val
                 935                 940                 945

 Ala Ser Gly His Glu Asn Gln Glu Leu Glu Arg Gln His Ala His
                 950                 955                 960

 Ile Gly Val Met Val Glu Phe Ser Ile Ala Leu Met Ser Lys Leu
                 965                 970                 975

 Asp Gly Ile Asn Arg His Ser Phe Asn Ser Phe Arg Leu Arg Val
                 980                 985                 990

 Gly Ile Asn His Gly Pro Val Ile Ala Gly Val Ile Gly Ala Arg
                 995                1000                1005

 Lys Pro Gln Tyr Asp Ile Trp Gly Asn Thr Val Asn Val Ala Ser
                1010                1015                1020

 Arg Met Glu Ser Thr Gly Glu Leu Gly Lys Ile Gln Val Thr Glu
                1025                1030                1035

 Glu Thr Cys Thr Ile Leu Gln Gly Leu Gly Tyr Ser Cys Glu Cys
                1040                1045                1050

 Arg Gly Leu Ile Asn Val Lys Gly Lys Gly Glu Leu Arg Thr Tyr
                1055                1060                1065

 Phe Val Cys Thr Asp Thr Ala Lys Phe Gln Gly Leu Gly Leu Asn
                1070                1075                1080

<210> 979
<211> 2281
<212> DNA
<213> Homo sapien

<400> 979
 cggggcggcg gcggcggcgt gaagtcactg ctgctctggg ttcgggttgg 50

 cgactgaagg cggtaccggc ctcccggaac agcccggggg agggcttagg 100

 tgcagaaggg caggctggcc gcggccggtt tggtctgggg accacgggct 150

 ggagcaggtg gaaatttaaa attgtttaca gtcaacactg tttccagcca 200

 tgggtttgtc tccatctgct cctgctgttg cagttcaggc ctcaaatgct 250

 tcagcgtccc caccttcagg atgcccgatg catgaaggga aaatgaaagg 300

 ctgtccagtg aatacagagc catctggccc aacctgtgag aagaaaacat 350

 actctgtgcc tgcccaccag gaacgcgcct atgagtacgt ggagtgtccc 400

 attaggggca ctgcggctga gaataaggag aacctagatc cttcaaatct 450

 gatgccacca ccaaatcaaa caccagctcc agatcagcca tttgcattgt 500

 ctactgtcag agaagagtca tccattccga gagcagattc agagaaaaag 550

 tgggtttacc cttctgagca gatgttctgg aatgcaatgt taaagaaagg 600

 gtggaagtgg aaggatgagg atatcagtca gaaggatatg tataatatca 650

 ttagaattca caatcagaat aacgagcagg cttggaagga gattttgaag 700

 tgggaagccc ttcatgctgc agagtgtcct tgtggtccat cattgatccg 750

 gtttggaggg aaagcaaaag agtattcacc aagggcacga attcgttcct 800

 ggatggggta tgagttgcct tttgataggc acgattggat cataaaccgt 850

 tgcgggacag aagttagata tgtgattgat tattatgatg gtggtgaagt 900

 caacaaggac taccagttca ccatcctgga cgtccgtcct gccttagatt 950

 cactttcggc agtatgggac agaatgaaag tcgcttggtg gcgttggacc 1000

 tcgtaaagca ctgtttcaga tggaaaaata taaactattt ttttctgagc 1050

 gatacattaa actattttcc ccagattgaa ttgcactcat gatgtaatgg 1100

 gaacttcaag tgggtaatca cactttttcc ttcacttaac gaaggatact 1150

 atgcactgtt cacttttgac ttgtgttgta ccttgcagtt tatagcagat 1200

 cattttgttt tcttcctact tagcttaagt gggaagcagt ctctcagttt 1250

 ttcctttacc tgcagtattg tctgtatatt tcatctcgaa aagcctgaac 1300

 aacctctgaa aaagagcttt taaaaagtga tgaaagttgc ttttttttct 1350

 tactattttc tcaggaatac tccagagatg taaagcctga gagtccatgg 1400

 tgatgctcaa gagctttcat ctggccaaat attttaacta aagctgttca 1450

 ttataaataa gaggtgatta tacctttttt aaaaaaagtt accattattt 1500

 ctaaagcccc tatggtatga ttgtgacctt taacaaaatg caaaggtata 1550

 cactggaaag gtactcagca aaattctctc caaattctga tttatatgaa 1600

 tttcttggac tggatagagt actttcaact ataccttcct ttggaacata 1650

 ccttttaaaa aatgttccct ttaaatcctg ttattctaat atgtaactct 1700

 gctcccaaca aacaggtctc ctcattgtcc ttggcatttg acaagttatc 1750

 ccaacttcga atctcatttc ttcctttgct ggcagcctcc acccttcccc 1800

 acatcagtcg gcctaatcca aaccttgaaa gcctggctta agtcccagta 1850

 tcagtgatgg tccccctcta aaacatgatt ttatatttgg ctgagtgtta 1900

 aaattcacaa gatgagcatt tttttcccag atggagaacg cttcaactca 1950

 gtctagattt tttttgtttg ttttaaggaa gctctaagtt tgccattgaa 2000

 actttttgta ccagtaatcc ataaactggt tgttctattt atagcagcat 2050

 gttacaaatg actgcttttt ttttttaact gtctatacta ttaaatcctt 2100

 taatttatcc tgaatgctgt agtgttaaat tagtggatga aattggcagt 2150

 ctgtgggtga ttaatttggt atggatttgt cagttttgtg tggagtttaa 2200

 gaaatagaac agccttaaac tctacatttc aaaatacttg tatattttaa 2250

 aataaagctg attagttcac aggttttgaa a 2281

<210> 980
<211> 237
<212> PRT
<213> Homo sapien

<400> 980
 Met Lys Gly Cys Pro Val Asn Thr Glu Pro Ser Gly Pro Thr Cys
   1               5                  10                  15

 Glu Lys Lys Thr Tyr Ser Val Pro Ala His Gln Glu Arg Ala Tyr
                  20                  25                  30

 Glu Tyr Val Glu Cys Pro Ile Arg Gly Thr Ala Ala Glu Asn Lys
                  35                  40                  45

 Glu Asn Leu Asp Pro Ser Asn Leu Met Pro Pro Pro Asn Gln Thr
                  50                  55                  60

 Pro Ala Pro Asp Gln Pro Phe Ala Leu Ser Thr Val Arg Glu Glu
                  65                  70                  75

 Ser Ser Ile Pro Arg Ala Asp Ser Glu Lys Lys Trp Val Tyr Pro
                  80                  85                  90

 Ser Glu Gln Met Phe Trp Asn Ala Met Leu Lys Lys Gly Trp Lys
                  95                 100                 105

 Trp Lys Asp Glu Asp Ile Ser Gln Lys Asp Met Tyr Asn Ile Ile
                 110                 115                 120

 Arg Ile His Asn Gln Asn Asn Glu Gln Ala Trp Lys Glu Ile Leu
                 125                 130                 135

 Lys Trp Glu Ala Leu His Ala Ala Glu Cys Pro Cys Gly Pro Ser
                 140                 145                 150

 Leu Ile Arg Phe Gly Gly Lys Ala Lys Glu Tyr Ser Pro Arg Ala
                 155                 160                 165

 Arg Ile Arg Ser Trp Met Gly Tyr Glu Leu Pro Phe Asp Arg His
                 170                 175                 180

 Asp Trp Ile Ile Asn Arg Cys Gly Thr Glu Val Arg Tyr Val Ile
                 185                 190                 195

 Asp Tyr Tyr Asp Gly Gly Glu Val Asn Lys Asp Tyr Gln Phe Thr
                 200                 205                 210

 Ile Leu Asp Val Arg Pro Ala Leu Asp Ser Leu Ser Ala Val Trp
                 215                 220                 225

 Asp Arg Met Lys Val Ala Trp Trp Arg Trp Thr Ser
                 230                 235

<210> 981
<211> 3702
<212> DNA
<213> Homo sapien

<400> 981
 gtttgttagg gagtcgtgtg cgtgccttgg tcgcttctgt agctccgagg 50

 gcaggttgcg gaagaaagcc caggcggtct gtggcccaga ggaaaggcct 100

 gcagcaggac gaggacctga gccaggaatg caggatggcg gcggtgaaga 150

 aggaaggggg tgctctgagt gaagccatgt ccctggaggg agatgaatgg 200

 gaactgagta aagaaaatgt acaaccttta aggcaagggc ggatcatgtc 250

 cacgcttcag ggagcactgg cacaagaatc tgcctgtaac aatactcttc 300

 agcagcagaa acgggcattt gaatatgaaa ttcgatttta cactggaaat 350

 gaccctctgg atgtttggga taggtatatc agctggacag agcagaacta 400

 tcctcaaggt gggaaggaga gtaatatgtc aacgttatta gaaagagctg 450

 tagaagcact acaaggagaa aaacgatatt atagtgatcc tcgatttctc 500

 aatctctggc ttaaattagg gcgtttatgc aatgagcctt tggatatgta 550

 cagttacttg cacaaccaag ggattggtgt ttcacttgct cagttctata 600

 tctcatgggc agaagaatat gaagctagag aaaactttag gaaagcagat 650

 gcgatatttc aggaagggat tcaacagaag gctgaaccac tagaaagact 700

 acagtcccag caccgacaat tccaagctcg agtgtctcgg caaactctgt 750

 tggcacttga gaaagaagaa gaggaggaag tttttgagtc ttctgtacca 800

 caacgaagca cactagctga actaaagagc aaagggaaaa agacagcaag 850

 agctccaatc atccgtgtag gaggtgctct caaggctcca agccagaaca 900

 gaggactcca aaatccattt cctcaacaga tgcaaaataa tagtagaatt 950

 actgtttttg atgaaaatgc tgatgaggct tctacagcag agttgtctaa 1000

 gcctacagtc cagccatgga tagcaccccc catgcccagg gccaaagaga 1050

 atgagctgca agcaggccct tggaacacag gcaggtcctt ggaacacagg 1100

 cctcgtggca atacagcttc actgatagct gtacccgctg tgcttcccag 1150

 tttcactcca tatgtggaag agactgcaca acagccagtt atgacaccat 1200

 gtaaaattga acctagtata aaccacatcc taagcaccag aaagcctgga 1250

 aaggaagaag gagattctct acaaagggtt cagagccatc agcaagcgtc 1300

 tgaggagaag aaagagaaga tgatgtattg taaggagaag atttatgcag 1350

 gagtagggga attctccttt gaagaaattc gggctgaagt tttccggaag 1400

 aaattaaaag agcaaaggga agccgagcta ttgaccagtg cagagaagag 1450

 agcagaaatg cagaaacaga ttgaagagat ggagaagaag ctaaaagaaa 1500

 tccaaactac tcagcaagaa agaacaggtg atcagcaaga agagacgatg 1550

 cctacaaagg agacaactaa actgcaaatt gcttccgagt ctcagaaaat 1600

 accaggaatg actctatcca gttctgtttg tcaagtaaac tgttgtgcca 1650

 gagaaacttc acttgcggag aacatttggc aggaacaacc tcattctaaa 1700

 ggtcccagtg tacctttctc catttttgat gagtttcttc tttcagaaaa 1750

 gaagaataaa agtcctcctg cagatccccc acgagtttta gctcaacgaa 1800

 gaccccttgc agttctcaaa acctcagaaa gcatcacctc aaatgaagat 1850

 gtgtctccag atgtttgtga tgaatttaca ggaattgaac ccttgagcga 1900

 ggatgccatt atcacaggct tcagaaatgt aacaatttgt cctaacccag 1950

 aagacacttg tgactttgcc agagcagctc gttttgtatc cactcctttt 2000

 catgagataa tgtccttgaa ggatctccct tctgatcctg agagactgtt 2050

 accggaagaa gatctagatg taaagacctc tgaggaccag cagacagctt 2100

 gtggcactat ctacagtcag actctcagca tcaagaagct gagcccaatt 2150

 attgaagaca gtcgtgaagc cacacactcc tctggcttct ctggttcttc 2200

 tgcctcggtt gcaagcacct cctccatcaa atgtcttcaa attcctgaga 2250

 aactagaact tactaatgag acttcagaaa accctactca gtcaccatgg 2300

 tgttcacagt atcgcagaca gctactgaag tccctaccag agttaagtgc 2350

 ctctgcagag ttgtgtatag aagacagacc aatgcctaag ttggaaattg 2400

 agaaggaaat tgaattaggt aatgaggatt actgcattaa acgagaatac 2450

 ctaatatgtg aagattacaa gttattctgg gtggcgccaa gaaactctgc 2500

 agaattaaca gtaataaagg tatcttctca acctgtccca tgggactttt 2550

 atatcaacct caagttaaag gaacgtttaa atgaagattt tgatcatttt 2600

 tgcagctgtt atcaatatca agatggctgt attgtttggc accaatatat 2650

 aaactgcttc acccttcagg atcttctcca acacagtgaa tatattaccc 2700

 atgaaataac agtgttgatt atttataacc ttttgacaat agtggagatg 2750

 ctacacaaag cagaaatagt ccatggtgac ttgagtccaa ggtgtctgat 2800

 tctcagaaac agaatccacg atccctatga ttgtaacaag aacaatcaag 2850

 ctttgaagat agtggacttt tcctacagtg ttgaccttag ggtgcagctg 2900

 gatgttttta ccctcagcgg ctttcggact gtacagatcc tggaaggaca 2950

 aaagatcctg gctaactgtt cttctcccta ccaggtagac ctgtttggta 3000

 tagcagattt agcacattta ctattgttca aggaacacct acaggtcttc 3050

 tgggatgggt ccttctggaa acttagccaa aatatttctg agctaaaaga 3100

 tggtgaattg tggaataaat tctttgtgcg gattctgaat gccaatgatg 3150

 aggccacagt gtctgttctt ggggagcttg cagcagaaat gaatggggtt 3200

 tttgacacta cattccaaag tcacctgaac aaagccttat ggaaggtagg 3250

 gaagttaact agtcctgggg ctttgctctt tcagtgagct aggcaatcaa 3300

 gtctcacaga ttgctgcctc agagcaatgg ttgtattgtg gaacactgaa 3350

 actgtatgtg ctgtaattta atttaggaca catttagatg cactaccatt 3400

 gctgttctac tttttggtac aggtatattt tgacgtcact gatatttttt 3450

 atacagtgat atacttactc atggccttgt ctaacttttg tgaagaacta 3500

 ttttattcta aacagactca ttacaaatgg ttaccttgtt atttaaccca 3550

 tttgtctcta cttttccctg tacttttccc atttgtaatt tgtaaaatgt 3600

 tctcttatga tcaccatgta ttttgtaaat aataaaatag tatctgttaa 3650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3700

 aa 3702

<210> 982
<211> 1050
<212> PRT
<213> Homo sapien

<400> 982
 Met Ala Ala Val Lys Lys Glu Gly Gly Ala Leu Ser Glu Ala Met
   1               5                  10                  15

 Ser Leu Glu Gly Asp Glu Trp Glu Leu Ser Lys Glu Asn Val Gln
                  20                  25                  30

 Pro Leu Arg Gln Gly Arg Ile Met Ser Thr Leu Gln Gly Ala Leu
                  35                  40                  45

 Ala Gln Glu Ser Ala Cys Asn Asn Thr Leu Gln Gln Gln Lys Arg
                  50                  55                  60

 Ala Phe Glu Tyr Glu Ile Arg Phe Tyr Thr Gly Asn Asp Pro Leu
                  65                  70                  75

 Asp Val Trp Asp Arg Tyr Ile Ser Trp Thr Glu Gln Asn Tyr Pro
                  80                  85                  90

 Gln Gly Gly Lys Glu Ser Asn Met Ser Thr Leu Leu Glu Arg Ala
                  95                 100                 105

 Val Glu Ala Leu Gln Gly Glu Lys Arg Tyr Tyr Ser Asp Pro Arg
                 110                 115                 120

 Phe Leu Asn Leu Trp Leu Lys Leu Gly Arg Leu Cys Asn Glu Pro
                 125                 130                 135

 Leu Asp Met Tyr Ser Tyr Leu His Asn Gln Gly Ile Gly Val Ser
                 140                 145                 150

 Leu Ala Gln Phe Tyr Ile Ser Trp Ala Glu Glu Tyr Glu Ala Arg
                 155                 160                 165

 Glu Asn Phe Arg Lys Ala Asp Ala Ile Phe Gln Glu Gly Ile Gln
                 170                 175                 180

 Gln Lys Ala Glu Pro Leu Glu Arg Leu Gln Ser Gln His Arg Gln
                 185                 190                 195

 Phe Gln Ala Arg Val Ser Arg Gln Thr Leu Leu Ala Leu Glu Lys
                 200                 205                 210

 Glu Glu Glu Glu Glu Val Phe Glu Ser Ser Val Pro Gln Arg Ser
                 215                 220                 225

 Thr Leu Ala Glu Leu Lys Ser Lys Gly Lys Lys Thr Ala Arg Ala
                 230                 235                 240

 Pro Ile Ile Arg Val Gly Gly Ala Leu Lys Ala Pro Ser Gln Asn
                 245                 250                 255

 Arg Gly Leu Gln Asn Pro Phe Pro Gln Gln Met Gln Asn Asn Ser
                 260                 265                 270

 Arg Ile Thr Val Phe Asp Glu Asn Ala Asp Glu Ala Ser Thr Ala
                 275                 280                 285

 Glu Leu Ser Lys Pro Thr Val Gln Pro Trp Ile Ala Pro Pro Met
                 290                 295                 300

 Pro Arg Ala Lys Glu Asn Glu Leu Gln Ala Gly Pro Trp Asn Thr
                 305                 310                 315

 Gly Arg Ser Leu Glu His Arg Pro Arg Gly Asn Thr Ala Ser Leu
                 320                 325                 330

 Ile Ala Val Pro Ala Val Leu Pro Ser Phe Thr Pro Tyr Val Glu
                 335                 340                 345

 Glu Thr Ala Gln Gln Pro Val Met Thr Pro Cys Lys Ile Glu Pro
                 350                 355                 360

 Ser Ile Asn His Ile Leu Ser Thr Arg Lys Pro Gly Lys Glu Glu
                 365                 370                 375

 Gly Asp Ser Leu Gln Arg Val Gln Ser His Gln Gln Ala Ser Glu
                 380                 385                 390

 Glu Lys Lys Glu Lys Met Met Tyr Cys Lys Glu Lys Ile Tyr Ala
                 395                 400                 405

 Gly Val Gly Glu Phe Ser Phe Glu Glu Ile Arg Ala Glu Val Phe
                 410                 415                 420

 Arg Lys Lys Leu Lys Glu Gln Arg Glu Ala Glu Leu Leu Thr Ser
                 425                 430                 435

 Ala Glu Lys Arg Ala Glu Met Gln Lys Gln Ile Glu Glu Met Glu
                 440                 445                 450

 Lys Lys Leu Lys Glu Ile Gln Thr Thr Gln Gln Glu Arg Thr Gly
                 455                 460                 465

 Asp Gln Gln Glu Glu Thr Met Pro Thr Lys Glu Thr Thr Lys Leu
                 470                 475                 480

 Gln Ile Ala Ser Glu Ser Gln Lys Ile Pro Gly Met Thr Leu Ser
                 485                 490                 495

 Ser Ser Val Cys Gln Val Asn Cys Cys Ala Arg Glu Thr Ser Leu
                 500                 505                 510

 Ala Glu Asn Ile Trp Gln Glu Gln Pro His Ser Lys Gly Pro Ser
                 515                 520                 525

 Val Pro Phe Ser Ile Phe Asp Glu Phe Leu Leu Ser Glu Lys Lys
                 530                 535                 540

 Asn Lys Ser Pro Pro Ala Asp Pro Pro Arg Val Leu Ala Gln Arg
                 545                 550                 555

 Arg Pro Leu Ala Val Leu Lys Thr Ser Glu Ser Ile Thr Ser Asn
                 560                 565                 570

 Glu Asp Val Ser Pro Asp Val Cys Asp Glu Phe Thr Gly Ile Glu
                 575                 580                 585

 Pro Leu Ser Glu Asp Ala Ile Ile Thr Gly Phe Arg Asn Val Thr
                 590                 595                 600

 Ile Cys Pro Asn Pro Glu Asp Thr Cys Asp Phe Ala Arg Ala Ala
                 605                 610                 615

 Arg Phe Val Ser Thr Pro Phe His Glu Ile Met Ser Leu Lys Asp
                 620                 625                 630

 Leu Pro Ser Asp Pro Glu Arg Leu Leu Pro Glu Glu Asp Leu Asp
                 635                 640                 645

 Val Lys Thr Ser Glu Asp Gln Gln Thr Ala Cys Gly Thr Ile Tyr
                 650                 655                 660

 Ser Gln Thr Leu Ser Ile Lys Lys Leu Ser Pro Ile Ile Glu Asp
                 665                 670                 675

 Ser Arg Glu Ala Thr His Ser Ser Gly Phe Ser Gly Ser Ser Ala
                 680                 685                 690

 Ser Val Ala Ser Thr Ser Ser Ile Lys Cys Leu Gln Ile Pro Glu
                 695                 700                 705

 Lys Leu Glu Leu Thr Asn Glu Thr Ser Glu Asn Pro Thr Gln Ser
                 710                 715                 720

 Pro Trp Cys Ser Gln Tyr Arg Arg Gln Leu Leu Lys Ser Leu Pro
                 725                 730                 735

 Glu Leu Ser Ala Ser Ala Glu Leu Cys Ile Glu Asp Arg Pro Met
                 740                 745                 750

 Pro Lys Leu Glu Ile Glu Lys Glu Ile Glu Leu Gly Asn Glu Asp
                 755                 760                 765

 Tyr Cys Ile Lys Arg Glu Tyr Leu Ile Cys Glu Asp Tyr Lys Leu
                 770                 775                 780

 Phe Trp Val Ala Pro Arg Asn Ser Ala Glu Leu Thr Val Ile Lys
                 785                 790                 795

 Val Ser Ser Gln Pro Val Pro Trp Asp Phe Tyr Ile Asn Leu Lys
                 800                 805                 810

 Leu Lys Glu Arg Leu Asn Glu Asp Phe Asp His Phe Cys Ser Cys
                 815                 820                 825

 Tyr Gln Tyr Gln Asp Gly Cys Ile Val Trp His Gln Tyr Ile Asn
                 830                 835                 840

 Cys Phe Thr Leu Gln Asp Leu Leu Gln His Ser Glu Tyr Ile Thr
                 845                 850                 855

 His Glu Ile Thr Val Leu Ile Ile Tyr Asn Leu Leu Thr Ile Val
                 860                 865                 870

 Glu Met Leu His Lys Ala Glu Ile Val His Gly Asp Leu Ser Pro
                 875                 880                 885

 Arg Cys Leu Ile Leu Arg Asn Arg Ile His Asp Pro Tyr Asp Cys
                 890                 895                 900

 Asn Lys Asn Asn Gln Ala Leu Lys Ile Val Asp Phe Ser Tyr Ser
                 905                 910                 915

 Val Asp Leu Arg Val Gln Leu Asp Val Phe Thr Leu Ser Gly Phe
                 920                 925                 930

 Arg Thr Val Gln Ile Leu Glu Gly Gln Lys Ile Leu Ala Asn Cys
                 935                 940                 945

 Ser Ser Pro Tyr Gln Val Asp Leu Phe Gly Ile Ala Asp Leu Ala
                 950                 955                 960

 His Leu Leu Leu Phe Lys Glu His Leu Gln Val Phe Trp Asp Gly
                 965                 970                 975

 Ser Phe Trp Lys Leu Ser Gln Asn Ile Ser Glu Leu Lys Asp Gly
                 980                 985                 990

 Glu Leu Trp Asn Lys Phe Phe Val Arg Ile Leu Asn Ala Asn Asp
                 995                1000                1005

 Glu Ala Thr Val Ser Val Leu Gly Glu Leu Ala Ala Glu Met Asn
                1010                1015                1020

 Gly Val Phe Asp Thr Thr Phe Gln Ser His Leu Asn Lys Ala Leu
                1025                1030                1035

 Trp Lys Val Gly Lys Leu Thr Ser Pro Gly Ala Leu Leu Phe Gln
                1040                1045                1050

<210> 983
<211> 2665
<212> DNA
<213> Homo sapien

<400> 983
 ggctctgggc atcaccagcg gccccaggga aaaagaaaga aatgggaaac 50

 agcatgaaat ccacccctgc gcctgccgag aggcccctgc ccaacccgga 100

 gggactggat agcgacttcc ttgccgtgct aagtgactac ccgtctcctg 150

 acatcagccc cccgatattc cgccgagggg agaaactgcg tgtgatttct 200

 gatgaagggg gctggtggaa agctatttct cttagcactg gtcgagagag 250

 ttacatccct ggaatatgtg tggccagagt ttaccatggc tggctgtttg 300

 agggcctggg cagagacaag gccgaggagc tgctgcagct gccagacaca 350

 aaggtcggct ccttcatgat cagagagagt gagaccaaga aagggtttta 400

 ctcactgtcg gtgagacaca ggcaggtaaa gcattaccgc attttccgtc 450

 tgccgaacaa ctggtactac atttccccga ggctcacctt ccagtgcctg 500

 gaggacctgg tgaaccacta ttctgaggtg gctgatggcc tgtgctgtgt 550

 gctcaccacg ccctgcctga cacaaagcac ggctgcccca gcagtgaggg 600

 cctccagctc acctgtcacc ttgcgtcaga agactgtgga ctggaggaga 650

 gtgtccagac tgcaggagga ccccgaggga acagagaacc cgcttggggt 700

 agacgagtcc cttttcagct atggccttcg agagagcatt gcctcttacc 750

 tgtccctgac cagtgaggac aacacctcct ttgatcgaaa gaagaaaagc 800

 atctccctga tgtatggtgg cagcaagaga aagagctcat tcttctcatc 850

 accaccttac tttgaggact agccaagaac agacacaatg gttcatgccc 900

 aaaaggaaca gaagttccaa ctattgcctg ggatcttgcg aaaagcgagg 950

 ttccctgatc cctgggagcc tcacgtattt tagaagccaa gagaagccac 1000

 atggagactc aaattcgcat cttctctatc cacatcatga ccaaaggaac 1050

 ccctccctgg tgtctgatca gggctgtggc atcacaaaac attggatcat 1100

 gacatgtcgg gcgatgcttg gaaaagccca gcatgtatgt atgcacacat 1150

 tgtgtgtgtg ggaaggacaa agccactctc acaagaaagg gcaccaggac 1200

 tgctctccaa ggaactggac ctgtccagac agttacactc caaggtcatt 1250

 ggagagaact tctgtatggg caagcctgag agggagagga aacaaaagct 1300

 gtgtcctggc agaaggtctg ggtttgcaga tgggtgccct gaatggaact 1350

 actttaacta atccataggg acttctggta tgctttcctc tctttttaaa 1400

 ggaacttcgt gacactaaac attagcccaa aggacttctt agccttcaat 1450

 tgggagatac ctttggtctg ctcctgcacc aaagccatat gggtggaagt 1500

 cagttggcct ccctggttct gcagagggcc agaagaatga gagagaggaa 1550

 gactgctggc agggaaatcg aggaggcgag actagaactg caccagcttc 1600

 cctgatgtct gcagccatgg ctttgcagcg caaacagaac ttctctggga 1650

 tgctgggatt cttgcctgta tgaatgcatc aagtattcat ttattgcccg 1700

 aataggcatt gcattaagtc ctctgttagg tgtcaggcaa gccaaaaaaa 1750

 aaaaaaagat gctaagtcct aacccccaac agaagtgttc acagtgtaga 1800

 cgggaaaaaa tgtataaaca aatgtgtaaa aagagaaatc agctcatggc 1850

 ttaggatgga attagagaca ggtgagggac actcaggagc tcattttcca 1900

 gctgctcttc agagtggaag ggctggctgg atcgggtagg taagaatagc 1950

 tggatttttt agaaaagaaa tggatacagt ctaaagaatt aactcacccg 2000

 gtactttatt ctaagaaggg tctggcatcc atatgaggaa aaatgctcag 2050

 ctccaggaaa gatggggagt ccaagtggat taatgatgtc atgcataatt 2100

 ttaagagaca agggagaaaa cacaatgtat agccagagaa ggagaagctc 2150

 ccatccaaat cctactagga agagagtggg ctgcagatga atctgtgact 2200

 catgtttccc tgtttcaaag ggatcctggg gaaggagggg aacatgcttg 2250

 cagtatctct ccctgtctgt ctgctcacat aagcattccg tccatctaag 2300

 ctcatcgtgc tactggtatg tgtatgtgca gttacacagt ttcctgtatc 2350

 ataaatccta gtgtgtttat acaaggagac atctgtggtt tccccaaccg 2400

 ttccaaaagg ctatttcaaa ggaaccagcc cacgtatgag aaatgaatgt 2450

 aacactgtgg acattgactt cccgcataag gcagggtgac cccctgaact 2500

 ccagatgttt gcacagtatc ttatgtgttg ttttccgttg tgacgaatgt 2550

 gattggaaca tttggggagc acccagaggg atttttcagt gggaagcatt 2600

 acactttgct aaatcatgta tttattcctg attaaaacaa acctaataaa 2650

 tatttaaccc ttggc 2665

<210> 984
<211> 276
<212> PRT
<213> Homo sapien

<400> 984
 Met Gly Asn Ser Met Lys Ser Thr Pro Ala Pro Ala Glu Arg Pro
   1               5                  10                  15

 Leu Pro Asn Pro Glu Gly Leu Asp Ser Asp Phe Leu Ala Val Leu
                  20                  25                  30

 Ser Asp Tyr Pro Ser Pro Asp Ile Ser Pro Pro Ile Phe Arg Arg
                  35                  40                  45

 Gly Glu Lys Leu Arg Val Ile Ser Asp Glu Gly Gly Trp Trp Lys
                  50                  55                  60

 Ala Ile Ser Leu Ser Thr Gly Arg Glu Ser Tyr Ile Pro Gly Ile
                  65                  70                  75

 Cys Val Ala Arg Val Tyr His Gly Trp Leu Phe Glu Gly Leu Gly
                  80                  85                  90

 Arg Asp Lys Ala Glu Glu Leu Leu Gln Leu Pro Asp Thr Lys Val
                  95                 100                 105

 Gly Ser Phe Met Ile Arg Glu Ser Glu Thr Lys Lys Gly Phe Tyr
                 110                 115                 120

 Ser Leu Ser Val Arg His Arg Gln Val Lys His Tyr Arg Ile Phe
                 125                 130                 135

 Arg Leu Pro Asn Asn Trp Tyr Tyr Ile Ser Pro Arg Leu Thr Phe
                 140                 145                 150

 Gln Cys Leu Glu Asp Leu Val Asn His Tyr Ser Glu Val Ala Asp
                 155                 160                 165

 Gly Leu Cys Cys Val Leu Thr Thr Pro Cys Leu Thr Gln Ser Thr
                 170                 175                 180

 Ala Ala Pro Ala Val Arg Ala Ser Ser Ser Pro Val Thr Leu Arg
                 185                 190                 195

 Gln Lys Thr Val Asp Trp Arg Arg Val Ser Arg Leu Gln Glu Asp
                 200                 205                 210

 Pro Glu Gly Thr Glu Asn Pro Leu Gly Val Asp Glu Ser Leu Phe
                 215                 220                 225

 Ser Tyr Gly Leu Arg Glu Ser Ile Ala Ser Tyr Leu Ser Leu Thr
                 230                 235                 240

 Ser Glu Asp Asn Thr Ser Phe Asp Arg Lys Lys Lys Ser Ile Ser
                 245                 250                 255

 Leu Met Tyr Gly Gly Ser Lys Arg Lys Ser Ser Phe Phe Ser Ser
                 260                 265                 270

 Pro Pro Tyr Phe Glu Asp
                 275

<210> 985
<211> 1366
<212> DNA
<213> Homo sapien

<400> 985
 cctgattcta ggctggtcac tactccgagc ctgtgacgtt tgcggcacca 50

 ggccgtcgac gatgcccagt gaaactctct gggaaattgc aaaagctgaa 100

 gtggaaaaaa ggggaattaa tggaagtgaa ggtgatggag ctgaaattgc 150

 agaaaaattt gttttcttca ttggcagtaa aaatggggga aagactacta 200

 ttattctaag gtgtcttgac agagatgaac caccaaaacc aaccttagct 250

 ttggaatata catatggaag aagagcaaaa gggcacaaca caccaaaaga 300

 tatcgctcac ttttgggaac tcggtggagg aacctcttta ttggacttaa 350

 tcagcatacc catcacaggt gacaccttac ggacgttttc tcttgttctc 400

 gttctggatc tttcaaaacc taatgatctc tggcccacca tggaaaatct 450

 cttgcaagcc acaaaaagcc atgtagacaa agtgataatg aaactgggaa 500

 agacaaatgc taaagcagtt tctgaaatga gacagaagat ctggaattat 550

 gccgaagatc atcctgatca tgaattaatt gacccatttc cggtacctct 600

 ggtcataatt ggaagtaaat atgatgtttt tcaggatttt gagtctgaga 650

 agagaaaggt aatatgcaag acacttcgat ttgttgcaca ttattatgga 700

 gcatcattaa tgtttaccag taaatcagaa gctctattac taaaaatacg 750

 tggagttatc aaccagttgg catttggcat tgacaaaagc aaatcaatat 800

 gtgtggatca gaataaaccg ctgtttatca cagcaggatt ggattctttc 850

 ggtcaaatag gatctcctcc tgttcctgaa aatgacattg gaaagcttca 900

 tgcccactca cctatggagt tgtggaaaaa agtgtatgaa aagctctttc 950

 caccaaagag tattaacacg ctgaaagata tcaaggaccc tgcgagagat 1000

 cctcagtatg ctgaaaatga agtcgatgag atgagaattc agaaggatct 1050

 ggaactggaa cagtacaaaa gaagttcttc caagtcttgg aaacaaatcg 1100

 agcttgattc ttgaacctat ttcaattatt gtatatttat ttcttctttt 1150

 ccaaatacaa ataagattat actgtgaatt aactattgtg gcaatatgtg 1200

 aagaaagtta aactgtataa tttgttaaag gacaagctgg atttcttgga 1250

 ctagtgcatc tccctgtata tcttgaagct ttttaaaagg aaaaattatt 1300

 gtagaaccac gtgtaatttt ttttaaaata aaagaatctt ctactaccta 1350

 cctctaaaaa aaaaaa 1366

<210> 986
<211> 350
<212> PRT
<213> Homo sapien

<400> 986
 Met Pro Ser Glu Thr Leu Trp Glu Ile Ala Lys Ala Glu Val Glu
   1               5                  10                  15

 Lys Arg Gly Ile Asn Gly Ser Glu Gly Asp Gly Ala Glu Ile Ala
                  20                  25                  30

 Glu Lys Phe Val Phe Phe Ile Gly Ser Lys Asn Gly Gly Lys Thr
                  35                  40                  45

 Thr Ile Ile Leu Arg Cys Leu Asp Arg Asp Glu Pro Pro Lys Pro
                  50                  55                  60

 Thr Leu Ala Leu Glu Tyr Thr Tyr Gly Arg Arg Ala Lys Gly His
                  65                  70                  75

 Asn Thr Pro Lys Asp Ile Ala His Phe Trp Glu Leu Gly Gly Gly
                  80                  85                  90

 Thr Ser Leu Leu Asp Leu Ile Ser Ile Pro Ile Thr Gly Asp Thr
                  95                 100                 105

 Leu Arg Thr Phe Ser Leu Val Leu Val Leu Asp Leu Ser Lys Pro
                 110                 115                 120

 Asn Asp Leu Trp Pro Thr Met Glu Asn Leu Leu Gln Ala Thr Lys
                 125                 130                 135

 Ser His Val Asp Lys Val Ile Met Lys Leu Gly Lys Thr Asn Ala
                 140                 145                 150

 Lys Ala Val Ser Glu Met Arg Gln Lys Ile Trp Asn Tyr Ala Glu
                 155                 160                 165

 Asp His Pro Asp His Glu Leu Ile Asp Pro Phe Pro Val Pro Leu
                 170                 175                 180

 Val Ile Ile Gly Ser Lys Tyr Asp Val Phe Gln Asp Phe Glu Ser
                 185                 190                 195

 Glu Lys Arg Lys Val Ile Cys Lys Thr Leu Arg Phe Val Ala His
                 200                 205                 210

 Tyr Tyr Gly Ala Ser Leu Met Phe Thr Ser Lys Ser Glu Ala Leu
                 215                 220                 225

 Leu Leu Lys Ile Arg Gly Val Ile Asn Gln Leu Ala Phe Gly Ile
                 230                 235                 240

 Asp Lys Ser Lys Ser Ile Cys Val Asp Gln Asn Lys Pro Leu Phe
                 245                 250                 255

 Ile Thr Ala Gly Leu Asp Ser Phe Gly Gln Ile Gly Ser Pro Pro
                 260                 265                 270

 Val Pro Glu Asn Asp Ile Gly Lys Leu His Ala His Ser Pro Met
                 275                 280                 285

 Glu Leu Trp Lys Lys Val Tyr Glu Lys Leu Phe Pro Pro Lys Ser
                 290                 295                 300

 Ile Asn Thr Leu Lys Asp Ile Lys Asp Pro Ala Arg Asp Pro Gln
                 305                 310                 315

 Tyr Ala Glu Asn Glu Val Asp Glu Met Arg Ile Gln Lys Asp Leu
                 320                 325                 330

 Glu Leu Glu Gln Tyr Lys Arg Ser Ser Ser Lys Ser Trp Lys Gln
                 335                 340                 345

 Ile Glu Leu Asp Ser
                 350

<210> 987
<211> 1366
<212> DNA
<213> Homo sapien

<400> 987
 cctgattcta ggctggtcac tactccgagc ctgtgacgtt tgcggcacca 50

 ggccgtcgac gatgcccagt gaaactctct gggaaattgc aaaagctgaa 100

 gtggaaaaaa ggggaattaa tggaagtgaa ggtgatggag ctgaaattgc 150

 agaaaaattt gttttcttca ttggcagtaa aaatggggga aagactacta 200

 ttattctaag gtgtcttgac agagatgaac caccaaaacc aaccttagct 250

 ttggaatata catatggaag aagagcaaaa gggcacaaca caccaaaaga 300

 tatcgctcac ttttgggaac tcggtggagg aacctcttta ttggacttaa 350

 tcagcatacc catcacaggt gacaccttac ggacgttttc tcttgttctc 400

 gttctggatc tttcaaaacc taatgatctc tggcccacca tggaaaatct 450

 cttgcaagcc acaaaaagcc atgtagacaa agtgataatg aaactgggaa 500

 agacaaatgc taaagcagtt tctgaaatga gacagaagat ctggaattat 550

 gccgaagatc atcctgatca tgaattaatt gacccatttc cggtacctct 600

 ggtcataatt ggaagtaaat atgatgtttt tcaggatttt gagtctgaga 650

 agagaaaggt aatatgcaag acacttcgat ttgttgcaca ttattatgga 700

 gcatcattaa tgtttaccag taaatcagaa gctctattac taaaaatacg 750

 tggagttatc aaccagttgg catttggcat tgacaaaagc aaatcaatat 800

 gtgtggatca gaataaaccg ctgtttatca cagcaggatt ggattctttc 850

 ggtcaaatag gatctcctcc tgttcctgaa aatgacattg gaaagcttca 900

 tgcccactca cctatggagt tgtggaaaaa agtgtatgaa aagctctttc 950

 caccaaagag tattaacacg ctgaaagata tcaaggaccc tgcgagagat 1000

 cctcagtatg ctgaaaatga agtcgatgag atgagaattc agaaggatct 1050

 ggaactggaa cagtacaaaa gaagttcttc caagtcttgg aaacaaatcg 1100

 agcttgattc ttgaacctat ttcaattatt gtatatttat ttcttctttt 1150

 ccaaatacaa ataagattat actgtgaatt aactattgtg gcaatatgtg 1200

 aagaaagtta aactgtataa tttgttaaag gacaagctgg atttcttgga 1250

 ctagtgcatc tccctgtata tcttgaagct ttttaaaagg aaaaattatt 1300

 gtagaaccac gtgtaatttt ttttaaaata aaagaatctt ctactaccta 1350

 cctctaaaaa aaaaaa 1366

<210> 988
<211> 350
<212> PRT
<213> Homo sapien

<400> 988
 Met Pro Ser Glu Thr Leu Trp Glu Ile Ala Lys Ala Glu Val Glu
   1               5                  10                  15

 Lys Arg Gly Ile Asn Gly Ser Glu Gly Asp Gly Ala Glu Ile Ala
                  20                  25                  30

 Glu Lys Phe Val Phe Phe Ile Gly Ser Lys Asn Gly Gly Lys Thr
                  35                  40                  45

 Thr Ile Ile Leu Arg Cys Leu Asp Arg Asp Glu Pro Pro Lys Pro
                  50                  55                  60

 Thr Leu Ala Leu Glu Tyr Thr Tyr Gly Arg Arg Ala Lys Gly His
                  65                  70                  75

 Asn Thr Pro Lys Asp Ile Ala His Phe Trp Glu Leu Gly Gly Gly
                  80                  85                  90

 Thr Ser Leu Leu Asp Leu Ile Ser Ile Pro Ile Thr Gly Asp Thr
                  95                 100                 105

 Leu Arg Thr Phe Ser Leu Val Leu Val Leu Asp Leu Ser Lys Pro
                 110                 115                 120

 Asn Asp Leu Trp Pro Thr Met Glu Asn Leu Leu Gln Ala Thr Lys
                 125                 130                 135

 Ser His Val Asp Lys Val Ile Met Lys Leu Gly Lys Thr Asn Ala
                 140                 145                 150

 Lys Ala Val Ser Glu Met Arg Gln Lys Ile Trp Asn Tyr Ala Glu
                 155                 160                 165

 Asp His Pro Asp His Glu Leu Ile Asp Pro Phe Pro Val Pro Leu
                 170                 175                 180

 Val Ile Ile Gly Ser Lys Tyr Asp Val Phe Gln Asp Phe Glu Ser
                 185                 190                 195

 Glu Lys Arg Lys Val Ile Cys Lys Thr Leu Arg Phe Val Ala His
                 200                 205                 210

 Tyr Tyr Gly Ala Ser Leu Met Phe Thr Ser Lys Ser Glu Ala Leu
                 215                 220                 225

 Leu Leu Lys Ile Arg Gly Val Ile Asn Gln Leu Ala Phe Gly Ile
                 230                 235                 240

 Asp Lys Ser Lys Ser Ile Cys Val Asp Gln Asn Lys Pro Leu Phe
                 245                 250                 255

 Ile Thr Ala Gly Leu Asp Ser Phe Gly Gln Ile Gly Ser Pro Pro
                 260                 265                 270

 Val Pro Glu Asn Asp Ile Gly Lys Leu His Ala His Ser Pro Met
                 275                 280                 285

 Glu Leu Trp Lys Lys Val Tyr Glu Lys Leu Phe Pro Pro Lys Ser
                 290                 295                 300

 Ile Asn Thr Leu Lys Asp Ile Lys Asp Pro Ala Arg Asp Pro Gln
                 305                 310                 315

 Tyr Ala Glu Asn Glu Val Asp Glu Met Arg Ile Gln Lys Asp Leu
                 320                 325                 330

 Glu Leu Glu Gln Tyr Lys Arg Ser Ser Ser Lys Ser Trp Lys Gln
                 335                 340                 345

 Ile Glu Leu Asp Ser
                 350

<210> 989
<211> 2979
<212> DNA
<213> Homo sapien

<400> 989
 agcaaaccaa tcgcaagcct cgttgagtgg aaggggtggg atcttccccg 50

 gaagttttgg ttaaagcccc tccaatcagc ggctcggtgc ggcaagtttg 100

 aatttcgtgg aggctcgggt tgtgagggtt cctgcttcgg agtcggcggt 150

 ggtcgtccag accgagtgtt ctttactttt tgtttggttg aggtttcacg 200

 ctagaaggtg gctcaggatg tcttcatcac attttgccag tcgacacagg 250

 aaggatataa gtactgaaat gattagaact aaaattgctc ataggaaatc 300

 actgtctcag aaagaaaata gacataagga atacgaacga aatagacact 350

 ttggtttgaa agatgtaaac attccaacct tggaaggtag aattcttgtt 400

 gaattagatg agacatctca agagcttgtt ccagaaaaga ccaatgttaa 450

 gccaagggca atgaaaacta ttctaggtga tcaacgaaaa cagatgctcc 500

 aaaaatacaa agaagaaaag caacttcaaa aattgaaaga gcagagagag 550

 aaagctaaac gaggaatatt taaagtgggt cgttatagac ctgatatgcc 600

 ttgttttctt ttatcaaacc agaatgctgt gaaagctgag ccaaaaaagg 650

 ctattccatc ttctgtacgg attacaaggt caaaggccaa agaccaaatg 700

 gagcagacta agattgataa cgagagtgat gttcgagcaa tccgacctgg 750

 tccaagacaa acttctgaaa agaaagtgtc agacaaagag aaaaaagttg 800

 tgcagcctgt aatgcccacg tcgttgagaa tgactcgatc agctactcaa 850

 gcagcaaagc aggttcccag aacagtctca tctaccacag caagaaagcc 900

 agtcacaaga gctgctaatg aaaacgaacc agaaggaaag gtgccaagta 950

 aaggaagacc tgccaaaaat gtagaaacaa aacccgacaa gggtatttct 1000

 tgtaaagtcg atagtgaaga aaatactttg aattcacaaa ctaatgcaac 1050

 aagtggaatg aatccagatg gagtcttatc aaaaatggaa aacttacctg 1100

 agataaatac tgcaaaaata aaagggaaga attccttcgc acctaaggat 1150

 tttatgtttc agccactgga tggtctgaag acctatcaag taacacctat 1200

 gactcccaga agtgccaatg cttttttgac acccagttac acctggactc 1250

 ctttaaaaac agaagttgat gagtctcaag caacaaaaga aattttggca 1300

 caaaaatgta aaacttactc taccaagaca atacagcaag attcaaataa 1350

 attgccatgt cctttgggtc ctctaactgt ttggcatgaa gaacatgttt 1400

 taaataaaaa tgaagctact actaaaaatt taaatggcct tccaataaaa 1450

 gaagtcccat cacttgaaag aaatgaaggt cgaattgctc agccccacca 1500

 tggtgtgcca tatttcagaa atatcctcca gtcagaaact gagaaattaa 1550

 cttcacattg cttcgagtgg gacaggaaac ttgaattgga cattccagat 1600

 gatgctaaag atcttattcg cacagcagtt ggtcaaacaa gactccttat 1650

 gaaggaaagg tttaaacagt ttgaaggact ggttgatgat tgtgaatata 1700

 aacgaggtat aaaggagact acctgtacag atctggatgg attttgggat 1750

 atggttagtt ttcagataga agatgtaatc cacaaattca acaatctgat 1800

 caaacttgag gaatctgggt ggcaagtcaa taataatatg aatcataata 1850

 tgaacaaaaa tgtctttagg aaaaaagttg tctcaggtat agcaagtaaa 1900

 ccaaaacagg atgatgctgg aagaattgca gcgagaaatc gcctagctgc 1950

 cataaaaaat gcaatgagag agagaattag gcaggaagaa tgtgctgaaa 2000

 cagcagtttc tgtgatacca aaggaagttg ataaaatagt gttcgatgct 2050

 ggatttttca gagttgaaag tcctgttaaa ttattctcag gactttctgt 2100

 ctcttctgaa ggcccttctc aaagacttgg aacacctaag tctgtcaaca 2150

 aagctgtatc tcagagtaga aatgagatgg gcattccaca acaaactaca 2200

 tcaccagaaa atgccggtcc tcagaatacg aaaagtgaac atgtgaagaa 2250

 gactttgttt ttgagtattc ctgaaagcag gagcagcata gaagatgctc 2300

 agtgtcctgg attaccagat ttaattgaag aaaaccatgt tgtaaataag 2350

 acagacttga aggtggattg tttatccagt gagagaatga gtttgcctct 2400

 tcttgctggt ggagtagcag atgatattaa tactaacaaa aaagaaggaa 2450

 tttcagatgt tgtggaagga atggaactga attcttcaat tacatcacag 2500

 gatgttttga tgagtagccc tgaaaaaaat acagcttcac aaaatagcat 2550

 cttagaagaa ggggaaacta aaatttctca gtcagaacta tttgataata 2600

 aaagtctcac tactgaatgc caccttcttg attcaccagg tctaaactgc 2650

 agtaatccat ttactcagct ggagaggaga catcaagaac atgccagaca 2700

 catttctttt ggtggtaacc tgattacttt ttcacctcta caaccaggag 2750

 aattttgaat ttaaaaataa atccaaacat tttccttcat attatcaatg 2800

 cttatatatt ccttagacta ttgaaatttt ggagaaaatg tatttgtgtt 2850

 cacttctata gcatataatg ttttaatatt ctgtgttcat caaagtgtat 2900

 tttagatata ctctttctca agggaagtgg ggatattttg tacattttca 2950

 acacagaata aaaaatgtac tgtgccttg 2979

<210> 990
<211> 846
<212> PRT
<213> Homo sapien

<400> 990
 Met Ser Ser Ser His Phe Ala Ser Arg His Arg Lys Asp Ile Ser
   1               5                  10                  15

 Thr Glu Met Ile Arg Thr Lys Ile Ala His Arg Lys Ser Leu Ser
                  20                  25                  30

 Gln Lys Glu Asn Arg His Lys Glu Tyr Glu Arg Asn Arg His Phe
                  35                  40                  45

 Gly Leu Lys Asp Val Asn Ile Pro Thr Leu Glu Gly Arg Ile Leu
                  50                  55                  60

 Val Glu Leu Asp Glu Thr Ser Gln Glu Leu Val Pro Glu Lys Thr
                  65                  70                  75

 Asn Val Lys Pro Arg Ala Met Lys Thr Ile Leu Gly Asp Gln Arg
                  80                  85                  90

 Lys Gln Met Leu Gln Lys Tyr Lys Glu Glu Lys Gln Leu Gln Lys
                  95                 100                 105

 Leu Lys Glu Gln Arg Glu Lys Ala Lys Arg Gly Ile Phe Lys Val
                 110                 115                 120

 Gly Arg Tyr Arg Pro Asp Met Pro Cys Phe Leu Leu Ser Asn Gln
                 125                 130                 135

 Asn Ala Val Lys Ala Glu Pro Lys Lys Ala Ile Pro Ser Ser Val
                 140                 145                 150

 Arg Ile Thr Arg Ser Lys Ala Lys Asp Gln Met Glu Gln Thr Lys
                 155                 160                 165

 Ile Asp Asn Glu Ser Asp Val Arg Ala Ile Arg Pro Gly Pro Arg
                 170                 175                 180

 Gln Thr Ser Glu Lys Lys Val Ser Asp Lys Glu Lys Lys Val Val
                 185                 190                 195

 Gln Pro Val Met Pro Thr Ser Leu Arg Met Thr Arg Ser Ala Thr
                 200                 205                 210

 Gln Ala Ala Lys Gln Val Pro Arg Thr Val Ser Ser Thr Thr Ala
                 215                 220                 225

 Arg Lys Pro Val Thr Arg Ala Ala Asn Glu Asn Glu Pro Glu Gly
                 230                 235                 240

 Lys Val Pro Ser Lys Gly Arg Pro Ala Lys Asn Val Glu Thr Lys
                 245                 250                 255

 Pro Asp Lys Gly Ile Ser Cys Lys Val Asp Ser Glu Glu Asn Thr
                 260                 265                 270

 Leu Asn Ser Gln Thr Asn Ala Thr Ser Gly Met Asn Pro Asp Gly
                 275                 280                 285

 Val Leu Ser Lys Met Glu Asn Leu Pro Glu Ile Asn Thr Ala Lys
                 290                 295                 300

 Ile Lys Gly Lys Asn Ser Phe Ala Pro Lys Asp Phe Met Phe Gln
                 305                 310                 315

 Pro Leu Asp Gly Leu Lys Thr Tyr Gln Val Thr Pro Met Thr Pro
                 320                 325                 330

 Arg Ser Ala Asn Ala Phe Leu Thr Pro Ser Tyr Thr Trp Thr Pro
                 335                 340                 345

 Leu Lys Thr Glu Val Asp Glu Ser Gln Ala Thr Lys Glu Ile Leu
                 350                 355                 360

 Ala Gln Lys Cys Lys Thr Tyr Ser Thr Lys Thr Ile Gln Gln Asp
                 365                 370                 375

 Ser Asn Lys Leu Pro Cys Pro Leu Gly Pro Leu Thr Val Trp His
                 380                 385                 390

 Glu Glu His Val Leu Asn Lys Asn Glu Ala Thr Thr Lys Asn Leu
                 395                 400                 405

 Asn Gly Leu Pro Ile Lys Glu Val Pro Ser Leu Glu Arg Asn Glu
                 410                 415                 420

 Gly Arg Ile Ala Gln Pro His His Gly Val Pro Tyr Phe Arg Asn
                 425                 430                 435

 Ile Leu Gln Ser Glu Thr Glu Lys Leu Thr Ser His Cys Phe Glu
                 440                 445                 450

 Trp Asp Arg Lys Leu Glu Leu Asp Ile Pro Asp Asp Ala Lys Asp
                 455                 460                 465

 Leu Ile Arg Thr Ala Val Gly Gln Thr Arg Leu Leu Met Lys Glu
                 470                 475                 480

 Arg Phe Lys Gln Phe Glu Gly Leu Val Asp Asp Cys Glu Tyr Lys
                 485                 490                 495

 Arg Gly Ile Lys Glu Thr Thr Cys Thr Asp Leu Asp Gly Phe Trp
                 500                 505                 510

 Asp Met Val Ser Phe Gln Ile Glu Asp Val Ile His Lys Phe Asn
                 515                 520                 525

 Asn Leu Ile Lys Leu Glu Glu Ser Gly Trp Gln Val Asn Asn Asn
                 530                 535                 540

 Met Asn His Asn Met Asn Lys Asn Val Phe Arg Lys Lys Val Val
                 545                 550                 555

 Ser Gly Ile Ala Ser Lys Pro Lys Gln Asp Asp Ala Gly Arg Ile
                 560                 565                 570

 Ala Ala Arg Asn Arg Leu Ala Ala Ile Lys Asn Ala Met Arg Glu
                 575                 580                 585

 Arg Ile Arg Gln Glu Glu Cys Ala Glu Thr Ala Val Ser Val Ile
                 590                 595                 600

 Pro Lys Glu Val Asp Lys Ile Val Phe Asp Ala Gly Phe Phe Arg
                 605                 610                 615

 Val Glu Ser Pro Val Lys Leu Phe Ser Gly Leu Ser Val Ser Ser
                 620                 625                 630

 Glu Gly Pro Ser Gln Arg Leu Gly Thr Pro Lys Ser Val Asn Lys
                 635                 640                 645

 Ala Val Ser Gln Ser Arg Asn Glu Met Gly Ile Pro Gln Gln Thr
                 650                 655                 660

 Thr Ser Pro Glu Asn Ala Gly Pro Gln Asn Thr Lys Ser Glu His
                 665                 670                 675

 Val Lys Lys Thr Leu Phe Leu Ser Ile Pro Glu Ser Arg Ser Ser
                 680                 685                 690

 Ile Glu Asp Ala Gln Cys Pro Gly Leu Pro Asp Leu Ile Glu Glu
                 695                 700                 705

 Asn His Val Val Asn Lys Thr Asp Leu Lys Val Asp Cys Leu Ser
                 710                 715                 720

 Ser Glu Arg Met Ser Leu Pro Leu Leu Ala Gly Gly Val Ala Asp
                 725                 730                 735

 Asp Ile Asn Thr Asn Lys Lys Glu Gly Ile Ser Asp Val Val Glu
                 740                 745                 750

 Gly Met Glu Leu Asn Ser Ser Ile Thr Ser Gln Asp Val Leu Met
                 755                 760                 765

 Ser Ser Pro Glu Lys Asn Thr Ala Ser Gln Asn Ser Ile Leu Glu
                 770                 775                 780

 Glu Gly Glu Thr Lys Ile Ser Gln Ser Glu Leu Phe Asp Asn Lys
                 785                 790                 795

 Ser Leu Thr Thr Glu Cys His Leu Leu Asp Ser Pro Gly Leu Asn
                 800                 805                 810

 Cys Ser Asn Pro Phe Thr Gln Leu Glu Arg Arg His Gln Glu His
                 815                 820                 825

 Ala Arg His Ile Ser Phe Gly Gly Asn Leu Ile Thr Phe Ser Pro
                 830                 835                 840

 Leu Gln Pro Gly Glu Phe
                 845

<210> 991
<211> 1731
<212> DNA
<213> Homo sapien

<400> 991
 gggggaggct gtgatgggtt gacaggtgcg tgacagtggg agctgctctc 50

 ggcacaagca tgtacggcaa aggcaagagt aacagcagcg ccgtcccgtc 100

 cgacagccag gcccgggaga agttagcact ctacgtatat gaatatctgc 150

 tccatgtagg agctcagaaa tcagctcaaa catttttatc agagataaga 200

 tgggaaaaaa acatcacatt gggggaacca ccaggattct tacattcttg 250

 gtggtgtgta ttttgggatc tctactgtgc agctccagag agacgtgaaa 300

 catgtgaaca ctcaagtgaa gcaaaagcct tccatgatta cagtgctgca 350

 gcagctccca gtccagtgct aggaaacatt cccccaggag atggcatgcc 400

 agtaggtcct gtaccaccag ggttctttca gccttttatg tcacctcggt 450

 accctggagg tccaaggccc ccattgagga tacctaatca ggcacttgga 500

 ggtgtcccag gaagtcagcc attactcccc agaggaatgg atccaactcg 550

 acaacaagga catccaaata tgggtgggcc aatgcagaga atgactcctc 600

 caagaggaat ggtgccctta ggaccacaga actatggagg tgcaatgaga 650

 cccccactga atgctttagg tggccctgga atgcctggaa tgaacatggg 700

 tccaggtggt ggtagacctt ggccaaaccc aacaaatgcc aattcaatac 750

 catactcctc agcatctcct gggaattatg taggtcctcc aggaggtgga 800

 gggccaccag gaacacccat catgcctagt ccagcagatt caaccaactc 850

 tggtgataac atgtatactt taatgaatgc agtacctcct ggacctaaca 900

 gacctaattt tccaatgggc cctgggtcag atggtcccat gggtggatta 950

 ggaggaatgg agtcacatca catgaatggc tctttaggct caggagatat 1000

 ggacagtatt tccaagaatt ctcccaataa tatgagcctg agtaatcaac 1050

 cgggcactcc aagggatgat ggcgaaatgg ggggaaattt cttaaatcct 1100

 tttcagagtg agagttactc ccctagcatg acaatgagcg tgtgatccat 1150

 taccaagtct cctcatgaaa accacagtga gtcagccctt cacagaacta 1200

 ctacggaaga aaattattca tcacagtgta cagttaaaca aaggaatctc 1250

 agtcacacca aaccaacctt ttcatttcct gctctctccc ctcttttgtg 1300

 aagaaagcgg gtccagatgt gattcaaaca actgtacgga gtggcatatt 1350

 agaattgccc taaactgaac tgcaaataat tatgtgtgta tgtatatgtg 1400

 tgggaaagag aatgtactgt atatgtgtat gttatacaga catatacaca 1450

 tacatacatt gacccacagg acattgtaaa atattatcac atgacatctt 1500

 aagtagaaat aagtagggac ttttattcca tccttttttt cacgtttaca 1550

 ttttaattat tacaagttgc tcctgccccc tccctgaact attttgtgct 1600

 gtgtatatca ctgctttata taagttattt tttaaggtga actcagatgt 1650

 tatggttttg tatatgtctg caatcatgga taggaataaa atcgcttatt 1700

 tgagagcttt caaaaaaaaa aaaaaaaaaa c 1731

<210> 992
<211> 361
<212> PRT
<213> Homo sapien

<400> 992
 Met Tyr Gly Lys Gly Lys Ser Asn Ser Ser Ala Val Pro Ser Asp
   1               5                  10                  15

 Ser Gln Ala Arg Glu Lys Leu Ala Leu Tyr Val Tyr Glu Tyr Leu
                  20                  25                  30

 Leu His Val Gly Ala Gln Lys Ser Ala Gln Thr Phe Leu Ser Glu
                  35                  40                  45

 Ile Arg Trp Glu Lys Asn Ile Thr Leu Gly Glu Pro Pro Gly Phe
                  50                  55                  60

 Leu His Ser Trp Trp Cys Val Phe Trp Asp Leu Tyr Cys Ala Ala
                  65                  70                  75

 Pro Glu Arg Arg Glu Thr Cys Glu His Ser Ser Glu Ala Lys Ala
                  80                  85                  90

 Phe His Asp Tyr Ser Ala Ala Ala Ala Pro Ser Pro Val Leu Gly
                  95                 100                 105

 Asn Ile Pro Pro Gly Asp Gly Met Pro Val Gly Pro Val Pro Pro
                 110                 115                 120

 Gly Phe Phe Gln Pro Phe Met Ser Pro Arg Tyr Pro Gly Gly Pro
                 125                 130                 135

 Arg Pro Pro Leu Arg Ile Pro Asn Gln Ala Leu Gly Gly Val Pro
                 140                 145                 150

 Gly Ser Gln Pro Leu Leu Pro Arg Gly Met Asp Pro Thr Arg Gln
                 155                 160                 165

 Gln Gly His Pro Asn Met Gly Gly Pro Met Gln Arg Met Thr Pro
                 170                 175                 180

 Pro Arg Gly Met Val Pro Leu Gly Pro Gln Asn Tyr Gly Gly Ala
                 185                 190                 195

 Met Arg Pro Pro Leu Asn Ala Leu Gly Gly Pro Gly Met Pro Gly
                 200                 205                 210

 Met Asn Met Gly Pro Gly Gly Gly Arg Pro Trp Pro Asn Pro Thr
                 215                 220                 225

 Asn Ala Asn Ser Ile Pro Tyr Ser Ser Ala Ser Pro Gly Asn Tyr
                 230                 235                 240

 Val Gly Pro Pro Gly Gly Gly Gly Pro Pro Gly Thr Pro Ile Met
                 245                 250                 255

 Pro Ser Pro Ala Asp Ser Thr Asn Ser Gly Asp Asn Met Tyr Thr
                 260                 265                 270

 Leu Met Asn Ala Val Pro Pro Gly Pro Asn Arg Pro Asn Phe Pro
                 275                 280                 285

 Met Gly Pro Gly Ser Asp Gly Pro Met Gly Gly Leu Gly Gly Met
                 290                 295                 300

 Glu Ser His His Met Asn Gly Ser Leu Gly Ser Gly Asp Met Asp
                 305                 310                 315

 Ser Ile Ser Lys Asn Ser Pro Asn Asn Met Ser Leu Ser Asn Gln
                 320                 325                 330

 Pro Gly Thr Pro Arg Asp Asp Gly Glu Met Gly Gly Asn Phe Leu
                 335                 340                 345

 Asn Pro Phe Gln Ser Glu Ser Tyr Ser Pro Ser Met Thr Met Ser
                 350                 355                 360

 Val


<210> 993
<211> 1395
<212> DNA
<213> Homo sapien

<400> 993
 cacagggccg ctcagaggcc gccgcaatgc tcccctcttt gcaggagtcg 50

 atggatggag atgaaaagga actagagagc agcgaagagg gaggctcagc 100

 cgaggagcgg agactcgagc cgccgtccag cagccactac tgtctttaca 150

 gctatcgcgg aagcagattg gcacagcaac gaggggacag tgaggacgga 200

 agcccaagtg gcacaaatgc agaaactccc tctggtgatg atttcagcct 250

 ctccttggca gatactaatc taccatccga agtggagcca gagctgcgca 300

 gtttcattgc taagcgtctt tcaagaggtg cagtctttga agggctgggt 350

 aatgttgcat ctgtggagct aaaaattcca ggttaccgag ttggttgtta 400

 ttactgcctt ttccaaaatg aaaaactgct tcctgaaaca gtaacgatag 450

 actctgaacg taacccttca gaatatgtgg tctgtttttt aggagggtct 500

 gaaaaaggac ttgagctttt caggcttgaa ttggacaagt acattcaagg 550

 gctgaaaaat aacatgaatt gtgaggcaag gggcctggag agtcacataa 600

 aatcctatct gagcagctgg tttgaggatg ttgtatgccc aatccaaagg 650

 gttgttcttc tctttcagga aaagcttacc tttctgctac atgctgcttt 700

 gagttacact cctgttgaag ttaaagaatc agatgaaaaa acaaagagag 750

 acattaacag gtttctgagt gtggccagtc ttcaaggact tattcatgaa 800

 ggcaccatga cttctttgtg catggccatg acagaggagc agcataagtc 850

 tgtggtcatc gattgcagca gctcccagcc tcagttctgc aatgcaggaa 900

 gtaaccggtt ttgtgaggat tggatgcaag cttttttaaa tggtgccaaa 950

 ggaggtaacc cttttttttt ccgacaagta ctggagaact ttaaactaaa 1000

 ggccatacaa gacacaaaca atttgaagag atttatccga caggcagaaa 1050

 tgaatcatta tgctttgttt aaatgttaca tgttcctaaa gaactgtggt 1100

 agtggagata cttttgaaga ttgttaaagt ggaacatgaa gaaatgcctg 1150

 aagccaaaaa tgtgatagct gtccttgaag aattcatgaa agaagctctt 1200

 gaccaaagtt tttgatcata tgttttgaga taattgtatg atcaagttgt 1250

 atatttaagt cttagtgttt gaaattgcag ttataattgt tcataggatt 1300

 gctatttaag atgatttgaa actcaatcca gattttcttt ttgtatttta 1350

 ccaatttaac ttaaataaaa atctgaagaa caaaaaaaaa aaaaa 1395

<210> 994
<211> 366
<212> PRT
<213> Homo sapien

<400> 994
 Met Leu Pro Ser Leu Gln Glu Ser Met Asp Gly Asp Glu Lys Glu
   1               5                  10                  15

 Leu Glu Ser Ser Glu Glu Gly Gly Ser Ala Glu Glu Arg Arg Leu
                  20                  25                  30

 Glu Pro Pro Ser Ser Ser His Tyr Cys Leu Tyr Ser Tyr Arg Gly
                  35                  40                  45

 Ser Arg Leu Ala Gln Gln Arg Gly Asp Ser Glu Asp Gly Ser Pro
                  50                  55                  60

 Ser Gly Thr Asn Ala Glu Thr Pro Ser Gly Asp Asp Phe Ser Leu
                  65                  70                  75

 Ser Leu Ala Asp Thr Asn Leu Pro Ser Glu Val Glu Pro Glu Leu
                  80                  85                  90

 Arg Ser Phe Ile Ala Lys Arg Leu Ser Arg Gly Ala Val Phe Glu
                  95                 100                 105

 Gly Leu Gly Asn Val Ala Ser Val Glu Leu Lys Ile Pro Gly Tyr
                 110                 115                 120

 Arg Val Gly Cys Tyr Tyr Cys Leu Phe Gln Asn Glu Lys Leu Leu
                 125                 130                 135

 Pro Glu Thr Val Thr Ile Asp Ser Glu Arg Asn Pro Ser Glu Tyr
                 140                 145                 150

 Val Val Cys Phe Leu Gly Gly Ser Glu Lys Gly Leu Glu Leu Phe
                 155                 160                 165

 Arg Leu Glu Leu Asp Lys Tyr Ile Gln Gly Leu Lys Asn Asn Met
                 170                 175                 180

 Asn Cys Glu Ala Arg Gly Leu Glu Ser His Ile Lys Ser Tyr Leu
                 185                 190                 195

 Ser Ser Trp Phe Glu Asp Val Val Cys Pro Ile Gln Arg Val Val
                 200                 205                 210

 Leu Leu Phe Gln Glu Lys Leu Thr Phe Leu Leu His Ala Ala Leu
                 215                 220                 225

 Ser Tyr Thr Pro Val Glu Val Lys Glu Ser Asp Glu Lys Thr Lys
                 230                 235                 240

 Arg Asp Ile Asn Arg Phe Leu Ser Val Ala Ser Leu Gln Gly Leu
                 245                 250                 255

 Ile His Glu Gly Thr Met Thr Ser Leu Cys Met Ala Met Thr Glu
                 260                 265                 270

 Glu Gln His Lys Ser Val Val Ile Asp Cys Ser Ser Ser Gln Pro
                 275                 280                 285

 Gln Phe Cys Asn Ala Gly Ser Asn Arg Phe Cys Glu Asp Trp Met
                 290                 295                 300

 Gln Ala Phe Leu Asn Gly Ala Lys Gly Gly Asn Pro Phe Phe Phe
                 305                 310                 315

 Arg Gln Val Leu Glu Asn Phe Lys Leu Lys Ala Ile Gln Asp Thr
                 320                 325                 330

 Asn Asn Leu Lys Arg Phe Ile Arg Gln Ala Glu Met Asn His Tyr
                 335                 340                 345

 Ala Leu Phe Lys Cys Tyr Met Phe Leu Lys Asn Cys Gly Ser Gly
                 350                 355                 360

 Asp Thr Phe Glu Asp Cys
                 365

<210> 995
<211> 5215
<212> DNA
<213> Homo sapien

<400> 995
 cgagcgcggc gcccttgagc tgcaccgcgg cgcaggtttg cgagccgact 50

 tgtcagccgg ccaagaaaag gaagctccgt cccttcccgc tcacccggct 100

 tccccacccc ttgtactcta aactctgcag agggcgagcg gcgcggccac 150

 ggaggcgccg aggaggagcg agccgccgcc gggcagcggc gtgccctcgg 200

 gggagagggc gccggagagg aggcggcggc gcggcggcga gggcgcggcg 250

 cgcgatggca gctgcttagc ccggcgggcg cggagcagcc ccgagctgtg 300

 gctggccagg cggtgcggct gggcggggga cgccgccgcc gttgctgccc 350

 ggcccggaga gatgagcacg gaggcggacg agggcatcac tttctctgtg 400

 ccacccttcg ccccctcggg cttctgcacc atccccgagg gcggcatctg 450

 caggagggga ggagcggcgg cggtgggcga gggcgaggag caccagctgc 500

 caccgccgcc gccgggcagc ttctggaacg tggagagcgc cgctgcccct 550

 ggcatcggtt gtccggcggc cacctcctcg agcagtgcca cccgaggccg 600

 gggcagctct gttggcgggg gcagccgacg gaccacggtg gcatatgtga 650

 tcaacgaagc gagccaaggg caactggtgg tggccgagag cgaggccctg 700

 cagagcttgc gggaggcgtg cgagacagtg ggcgccaccc tggaaaccct 750

 gcattttggg aaactcgact ttggagaaac caccgtgctg gaccgctttt 800

 acaatgcaga tattgcggtg gtggagatga gcgatgcctt ccggcagccg 850

 tccttgtttt accaccttgg ggtgagagaa agtttcagca tggccaacaa 900

 catcatcctc tactgtgata ctaactcgga ctctctgcag tcactgaagg 950

 aaataatttg ccagaagaat actatgtgca ctgggaacta cacctttgtt 1000

 ccttacatga taactccaca taacaaagtc tactgctgtg acagcagctt 1050

 catgaagggg ttgacagagc tcatgcaacc gaacttcgag ctgcttcttg 1100

 gacccatctg cttacctctt gtggatcgtt ttattcaact tttgaaggtg 1150

 gcacaagcaa gttctagcca gtacttccgg gaatctatac tcaatgacat 1200

 caggaaagct cgtaatttat acactggtaa agaattggca gctgagttgg 1250

 caagaattcg gcagcgagta gataatatcg aagtcttgac agcagatatt 1300

 gtcataaatc tgttactttc ctacagagat atccaggact atgattctat 1350

 tgtgaagctg gtagagactt tagaaaaact gccaaccttt gatttggcct 1400

 cccatcacca tgtgaagttt cattatgcat ttgcactgaa taggagaaat 1450

 ctccctggtg acagagcaaa agctcttgat attatgattc ccatggtgca 1500

 aagcgaagga caagttgctt cagatatgta ttgcctagtt ggtcgaatct 1550

 acaaagatat gtttttggac tctaatttca cggacactga aagcagagac 1600

 catggagctt cttggttcaa aaaggcattt gaatctgagc caacactaca 1650

 gtcaggaatt aattatgcgg tcctcctcct ggcagctgga caccagtttg 1700

 aatcttcctt tgagctccgg aaagttgggg tgaagctaag tagtcttctt 1750

 ggtaaaaagg gaaacttgga aaaactccag agctactggg aagttggatt 1800

 ttttctgggg gccagcgtcc tagccaatga ccacatgaga gtcattcaag 1850

 catctgaaaa gctttttaaa ctgaagacac cagcatggta cctcaagtct 1900

 attgtagaga caattttaat atataagcat tttgtgaaac tgaccacaga 1950

 acagcctgtg gccaagcaag aacttgtgga cttttggatg gatttcctgg 2000

 tcgaggccac aaagacagat gttactgtgg ttaggtttcc agtattaata 2050

 ttagaaccaa ccaaaatcta tcaaccttct tatttgtcta tcaacaatga 2100

 agttgaggaa aagacaatct ctatttggca cgtgcttcct gatgacaaga 2150

 aaggtataca tgagtggaat tttagtgcct cttctgtcag gggagtgagt 2200

 atttctaaat ttgaagaaag atgctgcttt ctttatgtgc ttcacaattc 2250

 tgatgatttc caaatctatt tctgtacaga acttcattgt aaaaagtttt 2300

 ttgagatggt gaacaccatt accgaagaga aggggagaag cacagaggaa 2350

 ggagactgtg aaagtgactt gctggagtat gactatgaat atgatgaaaa 2400

 tggtgacaga gtcgttttag gaaaaggcac ttatgggata gtctacgcag 2450

 gtcgggactt gagcaaccaa gtcagaattg ctattaagga aatcccagag 2500

 agagacagca gatactctca gcccctgcat gaagaaatag cattgcataa 2550

 acacctgaag cacaaaaata ttgtccagta tctgggctct ttcagtgaga 2600

 atggtttcat taaaatcttc atggagcagg tccctggagg aagtctttct 2650

 gctctccttc gttccaaatg gggtccatta aaagacaatg agcaaacaat 2700

 tggcttttat acaaagcaaa tactggaagg attaaaatat ctccatgaca 2750

 atcagatagt tcaccgggac ataaagggtg acaatgtgtt gattaatacc 2800

 tacagtggtg ttctcaagat ctctgacttc ggaacatcaa agaggcttgc 2850

 tggcataaac ccctgtactg aaacttttac tggtaccctc cagtatatgg 2900

 caccagaaat aatagataaa ggaccaagag gctacggaaa agcagcagac 2950

 atctggtctc tgggctgtac aatcattgaa atggccacag gaaaaccccc 3000

 attttatgaa ctgggagaac cacaagcagc tatgttcaag gtgggaatgt 3050

 ttaaagtcca ccctgagatc ccagagtcca tgtctgcaga ggccaaggca 3100

 ttcatactga aatgttttga accagatcct gacaagagag cctgtgctaa 3150

 cgacttgctt gttgatgagt ttttaaaagt ttcaagcaaa aagaaaaaga 3200

 cacaacctaa gctttcagct ctttcagctg gatcaaatga atatctcagg 3250

 agtatatcct tgccggtacc tgtgctggtg gaggacacca gcagcagcag 3300

 tgagtacggc tcagtttcac ccgacacgga gttgaaagtg gaccccttct 3350

 ctttcaaaac aagagccaag tcctgcggag aaagagatgt caagggaatt 3400

 cggacactct ttttgggcat tccagatgag aattttgaag atcacagtgc 3450

 tcctccttcc cctgaagaaa aagattctgg attcttcatg ctgaggaagg 3500

 acagtgagag gcgagctacc cttcacagga tcctgacgga agaccaagac 3550

 aaaattgtga gaaacctaat ggaatcttta gctcaggggg ctgaagaacc 3600

 gaaactaaaa tgggaacaca tcacaaccct cattgcaagc ctcagagaat 3650

 ttgtgagatc cactgaccga aaaatcatag ccaccacact gtcaaagctg 3700

 aaactggagc tggacttcga cagccatggc attagccaag tccaggtggt 3750

 actctttggt tttcaagatg ctgtcaataa agttcttcgg aatcataaca 3800

 tcaagccgca ctggatgttt gccttagaca gtatcattcg gaaggcggta 3850

 cagacagcca ttaccatcct ggttccagaa ctaaggccac atttcagcct 3900

 tgcatctgag agtgatactg ctgatcaaga agacttggat gtagaagatg 3950

 accatgagga acagccttca aatcaaactg tccgaagacc tcaggctgtc 4000

 attgaagatg ctgtggctac ctcaggcgtg agcacgctca gttctactgt 4050

 gtctcatgat tcccagagtg ctcaccggtc actgaatgta cagcttggaa 4100

 ggatgaaaat agaaaccaat agattactgg aagaattggt tcggaaagag 4150

 aaagaattac aagcactcct tcatcgagct attgaagaaa aagaccaaga 4200

 aattaaacac ctgaagctta agtcccaacc catagaaatt cctgaattgc 4250

 ctgtatttca tctaaattct tctggcacaa atactgaaga ttctgaactt 4300

 accgactggc tgagagtgaa tggagctgat gaagacacta taagccggtt 4350

 tttggctgaa gattatacac tattggatgt tctctactat gttacacgtg 4400

 atgacttaaa atgcttgaga ctaaggggag ggatgctgtg cacactgtgg 4450

 aaggctatca ttgactttcg aaacaaacag acttgactgt tgctcaatct 4500

 aatcttcgat ggaaattcta aaaattaata cagagctgat cttcttgggg 4550

 gtgggaaaat cgaagggaga ggagaaaggc gctgcacttt aaatccagta 4600

 tttgtttact catgttaaaa aaaaaaaaaa cagacaaaac acactgaaat 4650

 ttcctaacta catctatttc tataattttt aaggactctt cataaggact 4700

 cttaaaataa tcctgaacat tagaacccta atgttcagga agattttaat 4750

 ctaagcattt ttatggaaat atttttaatg cagcagctat tgcacttcag 4800

 ccaaatgttt atttcacaca aaacggatgt aacatttcat gtgatcgtgc 4850

 accactggaa caaaaccaaa atgtgaccat aactgtttag gcttctgtgt 4900

 gtttgtaata tgctctaata atctgagtag aaatgcgtaa tttcaattac 4950

 tgtataaagt ttatgttttt ttaagtgtgc agaatctgag agcaatggtt 5000

 tttacttctc tgtgttaatt gtaatattga ctctattttg taacttaagt 5050

 ttctgacctg tcgtacattt gtttgagtcg tttatgtact actgaactgt 5100

 accagttgca catgcttgaa ctgtagtaat gttagcttgt tctaaagcta 5150

 tccattgtgt catatttact ctaaaaatta aagagactct caacaaaaaa 5200

 aaaaaaaaaa aaaaa 5215

<210> 996
<211> 1374
<212> PRT
<213> Homo sapien

<400> 996
 Met Ser Thr Glu Ala Asp Glu Gly Ile Thr Phe Ser Val Pro Pro
   1               5                  10                  15

 Phe Ala Pro Ser Gly Phe Cys Thr Ile Pro Glu Gly Gly Ile Cys
                  20                  25                  30

 Arg Arg Gly Gly Ala Ala Ala Val Gly Glu Gly Glu Glu His Gln
                  35                  40                  45

 Leu Pro Pro Pro Pro Pro Gly Ser Phe Trp Asn Val Glu Ser Ala
                  50                  55                  60

 Ala Ala Pro Gly Ile Gly Cys Pro Ala Ala Thr Ser Ser Ser Ser
                  65                  70                  75

 Ala Thr Arg Gly Arg Gly Ser Ser Val Gly Gly Gly Ser Arg Arg
                  80                  85                  90

 Thr Thr Val Ala Tyr Val Ile Asn Glu Ala Ser Gln Gly Gln Leu
                  95                 100                 105

 Val Val Ala Glu Ser Glu Ala Leu Gln Ser Leu Arg Glu Ala Cys
                 110                 115                 120

 Glu Thr Val Gly Ala Thr Leu Glu Thr Leu His Phe Gly Lys Leu
                 125                 130                 135

 Asp Phe Gly Glu Thr Thr Val Leu Asp Arg Phe Tyr Asn Ala Asp
                 140                 145                 150

 Ile Ala Val Val Glu Met Ser Asp Ala Phe Arg Gln Pro Ser Leu
                 155                 160                 165

 Phe Tyr His Leu Gly Val Arg Glu Ser Phe Ser Met Ala Asn Asn
                 170                 175                 180

 Ile Ile Leu Tyr Cys Asp Thr Asn Ser Asp Ser Leu Gln Ser Leu
                 185                 190                 195

 Lys Glu Ile Ile Cys Gln Lys Asn Thr Met Cys Thr Gly Asn Tyr
                 200                 205                 210

 Thr Phe Val Pro Tyr Met Ile Thr Pro His Asn Lys Val Tyr Cys
                 215                 220                 225

 Cys Asp Ser Ser Phe Met Lys Gly Leu Thr Glu Leu Met Gln Pro
                 230                 235                 240

 Asn Phe Glu Leu Leu Leu Gly Pro Ile Cys Leu Pro Leu Val Asp
                 245                 250                 255

 Arg Phe Ile Gln Leu Leu Lys Val Ala Gln Ala Ser Ser Ser Gln
                 260                 265                 270

 Tyr Phe Arg Glu Ser Ile Leu Asn Asp Ile Arg Lys Ala Arg Asn
                 275                 280                 285

 Leu Tyr Thr Gly Lys Glu Leu Ala Ala Glu Leu Ala Arg Ile Arg
                 290                 295                 300

 Gln Arg Val Asp Asn Ile Glu Val Leu Thr Ala Asp Ile Val Ile
                 305                 310                 315

 Asn Leu Leu Leu Ser Tyr Arg Asp Ile Gln Asp Tyr Asp Ser Ile
                 320                 325                 330

 Val Lys Leu Val Glu Thr Leu Glu Lys Leu Pro Thr Phe Asp Leu
                 335                 340                 345

 Ala Ser His His His Val Lys Phe His Tyr Ala Phe Ala Leu Asn
                 350                 355                 360

 Arg Arg Asn Leu Pro Gly Asp Arg Ala Lys Ala Leu Asp Ile Met
                 365                 370                 375

 Ile Pro Met Val Gln Ser Glu Gly Gln Val Ala Ser Asp Met Tyr
                 380                 385                 390

 Cys Leu Val Gly Arg Ile Tyr Lys Asp Met Phe Leu Asp Ser Asn
                 395                 400                 405

 Phe Thr Asp Thr Glu Ser Arg Asp His Gly Ala Ser Trp Phe Lys
                 410                 415                 420

 Lys Ala Phe Glu Ser Glu Pro Thr Leu Gln Ser Gly Ile Asn Tyr
                 425                 430                 435

 Ala Val Leu Leu Leu Ala Ala Gly His Gln Phe Glu Ser Ser Phe
                 440                 445                 450

 Glu Leu Arg Lys Val Gly Val Lys Leu Ser Ser Leu Leu Gly Lys
                 455                 460                 465

 Lys Gly Asn Leu Glu Lys Leu Gln Ser Tyr Trp Glu Val Gly Phe
                 470                 475                 480

 Phe Leu Gly Ala Ser Val Leu Ala Asn Asp His Met Arg Val Ile
                 485                 490                 495

 Gln Ala Ser Glu Lys Leu Phe Lys Leu Lys Thr Pro Ala Trp Tyr
                 500                 505                 510

 Leu Lys Ser Ile Val Glu Thr Ile Leu Ile Tyr Lys His Phe Val
                 515                 520                 525

 Lys Leu Thr Thr Glu Gln Pro Val Ala Lys Gln Glu Leu Val Asp
                 530                 535                 540

 Phe Trp Met Asp Phe Leu Val Glu Ala Thr Lys Thr Asp Val Thr
                 545                 550                 555

 Val Val Arg Phe Pro Val Leu Ile Leu Glu Pro Thr Lys Ile Tyr
                 560                 565                 570

 Gln Pro Ser Tyr Leu Ser Ile Asn Asn Glu Val Glu Glu Lys Thr
                 575                 580                 585

 Ile Ser Ile Trp His Val Leu Pro Asp Asp Lys Lys Gly Ile His
                 590                 595                 600

 Glu Trp Asn Phe Ser Ala Ser Ser Val Arg Gly Val Ser Ile Ser
                 605                 610                 615

 Lys Phe Glu Glu Arg Cys Cys Phe Leu Tyr Val Leu His Asn Ser
                 620                 625                 630

 Asp Asp Phe Gln Ile Tyr Phe Cys Thr Glu Leu His Cys Lys Lys
                 635                 640                 645

 Phe Phe Glu Met Val Asn Thr Ile Thr Glu Glu Lys Gly Arg Ser
                 650                 655                 660

 Thr Glu Glu Gly Asp Cys Glu Ser Asp Leu Leu Glu Tyr Asp Tyr
                 665                 670                 675

 Glu Tyr Asp Glu Asn Gly Asp Arg Val Val Leu Gly Lys Gly Thr
                 680                 685                 690

 Tyr Gly Ile Val Tyr Ala Gly Arg Asp Leu Ser Asn Gln Val Arg
                 695                 700                 705

 Ile Ala Ile Lys Glu Ile Pro Glu Arg Asp Ser Arg Tyr Ser Gln
                 710                 715                 720

 Pro Leu His Glu Glu Ile Ala Leu His Lys His Leu Lys His Lys
                 725                 730                 735

 Asn Ile Val Gln Tyr Leu Gly Ser Phe Ser Glu Asn Gly Phe Ile
                 740                 745                 750

 Lys Ile Phe Met Glu Gln Val Pro Gly Gly Ser Leu Ser Ala Leu
                 755                 760                 765

 Leu Arg Ser Lys Trp Gly Pro Leu Lys Asp Asn Glu Gln Thr Ile
                 770                 775                 780

 Gly Phe Tyr Thr Lys Gln Ile Leu Glu Gly Leu Lys Tyr Leu His
                 785                 790                 795

 Asp Asn Gln Ile Val His Arg Asp Ile Lys Gly Asp Asn Val Leu
                 800                 805                 810

 Ile Asn Thr Tyr Ser Gly Val Leu Lys Ile Ser Asp Phe Gly Thr
                 815                 820                 825

 Ser Lys Arg Leu Ala Gly Ile Asn Pro Cys Thr Glu Thr Phe Thr
                 830                 835                 840

 Gly Thr Leu Gln Tyr Met Ala Pro Glu Ile Ile Asp Lys Gly Pro
                 845                 850                 855

 Arg Gly Tyr Gly Lys Ala Ala Asp Ile Trp Ser Leu Gly Cys Thr
                 860                 865                 870

 Ile Ile Glu Met Ala Thr Gly Lys Pro Pro Phe Tyr Glu Leu Gly
                 875                 880                 885

 Glu Pro Gln Ala Ala Met Phe Lys Val Gly Met Phe Lys Val His
                 890                 895                 900

 Pro Glu Ile Pro Glu Ser Met Ser Ala Glu Ala Lys Ala Phe Ile
                 905                 910                 915

 Leu Lys Cys Phe Glu Pro Asp Pro Asp Lys Arg Ala Cys Ala Asn
                 920                 925                 930

 Asp Leu Leu Val Asp Glu Phe Leu Lys Val Ser Ser Lys Lys Lys
                 935                 940                 945

 Lys Thr Gln Pro Lys Leu Ser Ala Leu Ser Ala Gly Ser Asn Glu
                 950                 955                 960

 Tyr Leu Arg Ser Ile Ser Leu Pro Val Pro Val Leu Val Glu Asp
                 965                 970                 975

 Thr Ser Ser Ser Ser Glu Tyr Gly Ser Val Ser Pro Asp Thr Glu
                 980                 985                 990

 Leu Lys Val Asp Pro Phe Ser Phe Lys Thr Arg Ala Lys Ser Cys
                 995                1000                1005

 Gly Glu Arg Asp Val Lys Gly Ile Arg Thr Leu Phe Leu Gly Ile
                1010                1015                1020

 Pro Asp Glu Asn Phe Glu Asp His Ser Ala Pro Pro Ser Pro Glu
                1025                1030                1035

 Glu Lys Asp Ser Gly Phe Phe Met Leu Arg Lys Asp Ser Glu Arg
                1040                1045                1050

 Arg Ala Thr Leu His Arg Ile Leu Thr Glu Asp Gln Asp Lys Ile
                1055                1060                1065

 Val Arg Asn Leu Met Glu Ser Leu Ala Gln Gly Ala Glu Glu Pro
                1070                1075                1080

 Lys Leu Lys Trp Glu His Ile Thr Thr Leu Ile Ala Ser Leu Arg
                1085                1090                1095

 Glu Phe Val Arg Ser Thr Asp Arg Lys Ile Ile Ala Thr Thr Leu
                1100                1105                1110

 Ser Lys Leu Lys Leu Glu Leu Asp Phe Asp Ser His Gly Ile Ser
                1115                1120                1125

 Gln Val Gln Val Val Leu Phe Gly Phe Gln Asp Ala Val Asn Lys
                1130                1135                1140

 Val Leu Arg Asn His Asn Ile Lys Pro His Trp Met Phe Ala Leu
                1145                1150                1155

 Asp Ser Ile Ile Arg Lys Ala Val Gln Thr Ala Ile Thr Ile Leu
                1160                1165                1170

 Val Pro Glu Leu Arg Pro His Phe Ser Leu Ala Ser Glu Ser Asp
                1175                1180                1185

 Thr Ala Asp Gln Glu Asp Leu Asp Val Glu Asp Asp His Glu Glu
                1190                1195                1200

 Gln Pro Ser Asn Gln Thr Val Arg Arg Pro Gln Ala Val Ile Glu
                1205                1210                1215

 Asp Ala Val Ala Thr Ser Gly Val Ser Thr Leu Ser Ser Thr Val
                1220                1225                1230

 Ser His Asp Ser Gln Ser Ala His Arg Ser Leu Asn Val Gln Leu
                1235                1240                1245

 Gly Arg Met Lys Ile Glu Thr Asn Arg Leu Leu Glu Glu Leu Val
                1250                1255                1260

 Arg Lys Glu Lys Glu Leu Gln Ala Leu Leu His Arg Ala Ile Glu
                1265                1270                1275

 Glu Lys Asp Gln Glu Ile Lys His Leu Lys Leu Lys Ser Gln Pro
                1280                1285                1290

 Ile Glu Ile Pro Glu Leu Pro Val Phe His Leu Asn Ser Ser Gly
                1295                1300                1305

 Thr Asn Thr Glu Asp Ser Glu Leu Thr Asp Trp Leu Arg Val Asn
                1310                1315                1320

 Gly Ala Asp Glu Asp Thr Ile Ser Arg Phe Leu Ala Glu Asp Tyr
                1325                1330                1335

 Thr Leu Leu Asp Val Leu Tyr Tyr Val Thr Arg Asp Asp Leu Lys
                1340                1345                1350

 Cys Leu Arg Leu Arg Gly Gly Met Leu Cys Thr Leu Trp Lys Ala
                1355                1360                1365

 Ile Ile Asp Phe Arg Asn Lys Gln Thr
                1370

<210> 997
<211> 5236
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4687
<223> Unknown base

<400> 997
 cgagcgcggc gcccttgagc tgcaccgcgg cgcaggtttg cgagccgact 50

 tgtcagccgg ccaagaaaag gaagctccgt cccttcccgc tcacccggct 100

 tccccacccc ttgtactcta aactctgcac agggcgagcg gcgcggccac 150

 tgatgcgccg aggaggagcg agccgccgcc gggcagcggc gtgccctcgg 200

 gggagagggc gccggataag agcggcggcg cggcggcgat ggcgcggcgc 250

 gcgatggcag ctgcttagcc cggcgggcgc ggagcagccc cgagctgtgg 300

 ctggccaggc ggtgcggctg ggcgggggac gccgccgccg ttgctgcccg 350

 gcccggagag atgagcacgg aggcggacga aggcatcact ttctctgtgc 400

 cacccttcgc cccctcgggc ttctgcacca tccccgaggg cggcatctgc 450

 aggaggggag gagcggcggc ggtgggcgag ggcgaggagc accagctgcc 500

 accgccgccg ccgggcagct tctggaacgt ggagagcgcc gctgcccctg 550

 gcatcggttg tccggcggcc acctcctcga gcagtgccac ccgaggccgg 600

 ggcagctctg ttggcggggg cagccgacgg accacggtgg catatgtgat 650

 caacgaagcg agccaagggc aactggtggt ggccgagagc gaggccctgc 700

 agagcttgcg ggaggcgtgc gagacagtgg gcgccaccct ggaaaccctg 750

 cattttggga aactcgactt tggagaaacc accgtgctgg accgctttta 800

 caatgcagat attgcggtgg tggagatgag cgatgccttc cggcagccgt 850

 ccttgtttta ccaccttggg gtgagagaaa gtttcagcat ggccaacaac 900

 atcatcctct actgtgatac taactcggac tctctgcagt cactgaagga 950

 aataatttgc cagaagaata ctatgtgcac tgggaactac acctttgttc 1000

 cttacatgat aactccacat aacaaagtct actgctgtga cagcagcttc 1050

 atgaaggggt tgacagagct catgcaaccg aacttcgagc tgcttcttgg 1100

 acccatctgc ttacctcttg tggatcgttt tattcaactt ttgaaggtgg 1150

 cacaagcaag ttctagccag tacttccggg aatctatact caatgacatc 1200

 aggaaagctc gtaatttata cactggtaaa gaattggcag ctgagttggc 1250

 aagaattcgg cagcgagtag ataatatcga agtcttgaca gcagatattg 1300

 tcataaatct gttactttcc tacagagata tccaggacta tgattctatt 1350

 gtgaagctgg tagagacttt agaaaaactg ccaacctttg atttggcctc 1400

 ccatcaccat gtgaagtttc attatgcatt tgcactgaat aggagaaatc 1450

 tccctggtga cagagcaaaa gctcttgata ttatgattcc catggtgcaa 1500

 agcgaaggac aagttgcttc agatatgtat tgcctagttg gtcgaatcta 1550

 caaagatatg tttttggact ctaatttcac ggacactgaa agcagagacc 1600

 atggagcttc ttggttcaaa aaggcatttg aatctgagcc aacactacag 1650

 tcaggaatta attatgcggt cctcctcctg gcagctggac accagtttga 1700

 atcttccttt gagctccgga aagttggggt gaagctaagt agtcttcttg 1750

 gtaaaaaggg aaacttggaa aaactccaga gctactggga agttggattt 1800

 tttctggggg ccagcgtcct agccaatgac cacatgagag tcattcaagc 1850

 atctgaaaag ctttttaaac tgaagacacc agcatggtac ctcaagtcta 1900

 ttgtagagac aattttaata tataagcatt ttgtgaaact gaccacagaa 1950

 cagcctgtgg ccaagcaaga acttgtggac ttttggatgg atttcctggt 2000

 cgaggccaca aagacagatg ttactgtggt taggtttcca gtattaatat 2050

 tagaaccaac caaaatctat caaccttctt atttgtctat caacaatgaa 2100

 gttgaggaaa agacaatctc tatttggcac gtgcttcctg atgacaagaa 2150

 aggtatacat gagtggaatt ttagtgcctc ttctgtcagg ggagtgagta 2200

 tttctaaatt tgaagaaaga tgctgctttc tttatgtgct tcacaattct 2250

 gatgatttcc aaatctattt ctgtacagaa cttcattgta aaaagttttt 2300

 tgagatggtg aacaccatta ccgaagagaa ggggagaagc acagaggaag 2350

 gagactgtga aagtgacttg ctggagtatg actatgaata tgatgaaaat 2400

 ggtgacagag tcgttttagg aaaaggcact tatgggatag tctacgcagg 2450

 tcgggacttg agcaaccaag tcagaattgc tattaaggaa atcccagaga 2500

 gagacagcag atactctcag cccctgcatg aagaaatagc attgcataaa 2550

 cacctgaagc acaaaaatat tgtccagtat ctgggctctt tcagtgagaa 2600

 tggtttcatt aaaatcttca tggagcaggt ccctggagga agtctttctg 2650

 ctctccttcg ttccaaatgg ggtccattaa aagacaatga gcaaacaatt 2700

 ggcttttata caaagcaaat actggaagga ttaaaatatc tccatgacaa 2750

 tcagatagtt caccgggaca taaagggtga caatgtgttg attaatacct 2800

 acagtggtgt tctcaagatc tctgacttcg gaacatcaaa gaggcttgct 2850

 ggcataaacc cctgtactga aacttttact ggtaccctcc agtatatggc 2900

 accagaaata atagataaag gaccaagagg ctacggaaaa gcagcagaca 2950

 tctggtctct gggctgtaca atcattgaaa tggccacagg aaaaccccca 3000

 ttttatgaac tgggagaacc acaagcagct atgttcaagg tgggaatgtt 3050

 taaagtccac cctgagatcc cagagtccat gtctgcagag gccaaggcat 3100

 tcatactgaa atgttttgaa ccagatcctg acaagagagc ctgtgctaac 3150

 gacttgcttg ttgatgagtt tttaaaagtt tcaagcaaaa agaaaaagac 3200

 acaacctaag ctttcagctc tttcagctgg atcaaatgaa tatctcagga 3250

 gtatatcctt gccggtacct gtgctggtgg aggacaccag cagcagcagt 3300

 gagtacggct cagtttcacc cgacacggag ttgaaagtgg accccttctc 3350

 tttcaaaaca agagccaagt cctgcggaga aagagatgtc aagggaattc 3400

 ggacactctt tttgggcatt ccagatgaga attttgaaga tcacagtgct 3450

 cctccttccc ctgaagaaaa agattctgga ttcttcatgc tgaggaagga 3500

 cagtgagagg cgagctaccc ttcacaggat cctgacggaa gaccaagaca 3550

 aaattgtgag aaacctaatg gaatctttag ctcagggggc tgaagaaccg 3600

 aaactaaaat gggaacacat cacaaccctc attgcaagcc tcagagaatt 3650

 tgtgagatcc actgaccgaa aaatcatagc caccacactg tcaaagctga 3700

 aactggagct ggacttcgac agccatggca ttagccaagt ccaggtggta 3750

 ctctttggtt ttcaagatgc tgtcaataaa gttcttcgga atcataacat 3800

 caagccgcac tggatgtttg ccttagacag tatcattcgg aaggcggtac 3850

 agacagccat taccatcctg gttccagaac taaggccaca tttcagcctt 3900

 gcatctgaga gtgatactgc tgatcaagaa gacttggatg tagaagatga 3950

 ccatgaggaa cagccttcaa atcaaactgt ccgaagacct caggctgtca 4000

 ttgaagatgc tgtggctacc tcaggcgtga gcacgctcag ttctactgtg 4050

 tctcatgatt cccagagtgc tcaccggtca ctgaatgtac agcttggaag 4100

 gatgaaaata gaaaccaata gattactgga agaattggtt cggaaagaga 4150

 aagaattaca agcactcctt catcgagcta ttgaagaaaa agaccaagaa 4200

 attaaacacc tgaagcttaa gtcccaaccc atagaaattc ctgaattgcc 4250

 tgtatttcat ctaaattctt ctggcacaaa tactgaagat tctgaactta 4300

 ccgactggct gagagtgaat ggagctgatg aagacactat aagccggttt 4350

 ttggctgaag attatacact attggatgtt ctctactatg ttacacgtga 4400

 tgacttaaaa tgcttgagac taaggggagg gatgctgtgc acactgtgga 4450

 aggctatcat tgactttcga aacaaacaga cttgactgtt gctcaatcta 4500

 atcttcgatg gaaattctaa aaattaatac agagctgatc ttcttggggg 4550

 tgggaaaatc gaagggagar gagaaaggcg ctgcmcttta aatccagtat 4600

 ttgtttactc atgttaaaaa aaaaaaaaac agacaaaaca cactgaaatt 4650

 tcctaactac atctatttct ataattttta aggactnttc ataaggactc 4700

 ttaaaataat cctgaacatt agaaccctaa tgttcaggaa gattttaatc 4750

 taagcatttt tatggaaata tttttaatgc agcagctatt gcacttcagc 4800

 caaatgttta tttcacacaa aacggatgta acattcatgt gatcgtgcac 4850

 ccactggaca aaccaaaatg tgaccataac tgtttaggtt ctgtgtgttt 4900

 gtaatatgtc taataatctg gagtagaaat gcgtaatttc aattactgta 4950

 taaagtttat gtttttttaa gtgtgcagaa tctgagagca atggttttta 5000

 cttctctgtg ttaattgtaa tattgactct attttgtaac ttaagtttct 5050

 gacctgtcgt acatttgttt gagtcgttta tgtactactg aactgtacca 5100

 gttgcacatg cttgaactgt agtaatgtta gcttgttcta aagctatcca 5150

 ttgtgtcata tttactctaa aaattaaaga gactctcaac aaaaaaaaaa 5200

 aaaaaaaaaa accatggtac ccggatcctc gaattc 5236

<210> 998
<211> 1374
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4687
<223> Unknown amino acid

<400> 998
 Met Ser Thr Glu Ala Asp Glu Gly Ile Thr Phe Ser Val Pro Pro
   1               5                  10                  15

 Phe Ala Pro Ser Gly Phe Cys Thr Ile Pro Glu Gly Gly Ile Cys
                  20                  25                  30

 Arg Arg Gly Gly Ala Ala Ala Val Gly Glu Gly Glu Glu His Gln
                  35                  40                  45

 Leu Pro Pro Pro Pro Pro Gly Ser Phe Trp Asn Val Glu Ser Ala
                  50                  55                  60

 Ala Ala Pro Gly Ile Gly Cys Pro Ala Ala Thr Ser Ser Ser Ser
                  65                  70                  75

 Ala Thr Arg Gly Arg Gly Ser Ser Val Gly Gly Gly Ser Arg Arg
                  80                  85                  90

 Thr Thr Val Ala Tyr Val Ile Asn Glu Ala Ser Gln Gly Gln Leu
                  95                 100                 105

 Val Val Ala Glu Ser Glu Ala Leu Gln Ser Leu Arg Glu Ala Cys
                 110                 115                 120

 Glu Thr Val Gly Ala Thr Leu Glu Thr Leu His Phe Gly Lys Leu
                 125                 130                 135

 Asp Phe Gly Glu Thr Thr Val Leu Asp Arg Phe Tyr Asn Ala Asp
                 140                 145                 150

 Ile Ala Val Val Glu Met Ser Asp Ala Phe Arg Gln Pro Ser Leu
                 155                 160                 165

 Phe Tyr His Leu Gly Val Arg Glu Ser Phe Ser Met Ala Asn Asn
                 170                 175                 180

 Ile Ile Leu Tyr Cys Asp Thr Asn Ser Asp Ser Leu Gln Ser Leu
                 185                 190                 195

 Lys Glu Ile Ile Cys Gln Lys Asn Thr Met Cys Thr Gly Asn Tyr
                 200                 205                 210

 Thr Phe Val Pro Tyr Met Ile Thr Pro His Asn Lys Val Tyr Cys
                 215                 220                 225

 Cys Asp Ser Ser Phe Met Lys Gly Leu Thr Glu Leu Met Gln Pro
                 230                 235                 240

 Asn Phe Glu Leu Leu Leu Gly Pro Ile Cys Leu Pro Leu Val Asp
                 245                 250                 255

 Arg Phe Ile Gln Leu Leu Lys Val Ala Gln Ala Ser Ser Ser Gln
                 260                 265                 270

 Tyr Phe Arg Glu Ser Ile Leu Asn Asp Ile Arg Lys Ala Arg Asn
                 275                 280                 285

 Leu Tyr Thr Gly Lys Glu Leu Ala Ala Glu Leu Ala Arg Ile Arg
                 290                 295                 300

 Gln Arg Val Asp Asn Ile Glu Val Leu Thr Ala Asp Ile Val Ile
                 305                 310                 315

 Asn Leu Leu Leu Ser Tyr Arg Asp Ile Gln Asp Tyr Asp Ser Ile
                 320                 325                 330

 Val Lys Leu Val Glu Thr Leu Glu Lys Leu Pro Thr Phe Asp Leu
                 335                 340                 345

 Ala Ser His His His Val Lys Phe His Tyr Ala Phe Ala Leu Asn
                 350                 355                 360

 Arg Arg Asn Leu Pro Gly Asp Arg Ala Lys Ala Leu Asp Ile Met
                 365                 370                 375

 Ile Pro Met Val Gln Ser Glu Gly Gln Val Ala Ser Asp Met Tyr
                 380                 385                 390

 Cys Leu Val Gly Arg Ile Tyr Lys Asp Met Phe Leu Asp Ser Asn
                 395                 400                 405

 Phe Thr Asp Thr Glu Ser Arg Asp His Gly Ala Ser Trp Phe Lys
                 410                 415                 420

 Lys Ala Phe Glu Ser Glu Pro Thr Leu Gln Ser Gly Ile Asn Tyr
                 425                 430                 435

 Ala Val Leu Leu Leu Ala Ala Gly His Gln Phe Glu Ser Ser Phe
                 440                 445                 450

 Glu Leu Arg Lys Val Gly Val Lys Leu Ser Ser Leu Leu Gly Lys
                 455                 460                 465

 Lys Gly Asn Leu Glu Lys Leu Gln Ser Tyr Trp Glu Val Gly Phe
                 470                 475                 480

 Phe Leu Gly Ala Ser Val Leu Ala Asn Asp His Met Arg Val Ile
                 485                 490                 495

 Gln Ala Ser Glu Lys Leu Phe Lys Leu Lys Thr Pro Ala Trp Tyr
                 500                 505                 510

 Leu Lys Ser Ile Val Glu Thr Ile Leu Ile Tyr Lys His Phe Val
                 515                 520                 525

 Lys Leu Thr Thr Glu Gln Pro Val Ala Lys Gln Glu Leu Val Asp
                 530                 535                 540

 Phe Trp Met Asp Phe Leu Val Glu Ala Thr Lys Thr Asp Val Thr
                 545                 550                 555

 Val Val Arg Phe Pro Val Leu Ile Leu Glu Pro Thr Lys Ile Tyr
                 560                 565                 570

 Gln Pro Ser Tyr Leu Ser Ile Asn Asn Glu Val Glu Glu Lys Thr
                 575                 580                 585

 Ile Ser Ile Trp His Val Leu Pro Asp Asp Lys Lys Gly Ile His
                 590                 595                 600

 Glu Trp Asn Phe Ser Ala Ser Ser Val Arg Gly Val Ser Ile Ser
                 605                 610                 615

 Lys Phe Glu Glu Arg Cys Cys Phe Leu Tyr Val Leu His Asn Ser
                 620                 625                 630

 Asp Asp Phe Gln Ile Tyr Phe Cys Thr Glu Leu His Cys Lys Lys
                 635                 640                 645

 Phe Phe Glu Met Val Asn Thr Ile Thr Glu Glu Lys Gly Arg Ser
                 650                 655                 660

 Thr Glu Glu Gly Asp Cys Glu Ser Asp Leu Leu Glu Tyr Asp Tyr
                 665                 670                 675

 Glu Tyr Asp Glu Asn Gly Asp Arg Val Val Leu Gly Lys Gly Thr
                 680                 685                 690

 Tyr Gly Ile Val Tyr Ala Gly Arg Asp Leu Ser Asn Gln Val Arg
                 695                 700                 705

 Ile Ala Ile Lys Glu Ile Pro Glu Arg Asp Ser Arg Tyr Ser Gln
                 710                 715                 720

 Pro Leu His Glu Glu Ile Ala Leu His Lys His Leu Lys His Lys
                 725                 730                 735

 Asn Ile Val Gln Tyr Leu Gly Ser Phe Ser Glu Asn Gly Phe Ile
                 740                 745                 750

 Lys Ile Phe Met Glu Gln Val Pro Gly Gly Ser Leu Ser Ala Leu
                 755                 760                 765

 Leu Arg Ser Lys Trp Gly Pro Leu Lys Asp Asn Glu Gln Thr Ile
                 770                 775                 780

 Gly Phe Tyr Thr Lys Gln Ile Leu Glu Gly Leu Lys Tyr Leu His
                 785                 790                 795

 Asp Asn Gln Ile Val His Arg Asp Ile Lys Gly Asp Asn Val Leu
                 800                 805                 810

 Ile Asn Thr Tyr Ser Gly Val Leu Lys Ile Ser Asp Phe Gly Thr
                 815                 820                 825

 Ser Lys Arg Leu Ala Gly Ile Asn Pro Cys Thr Glu Thr Phe Thr
                 830                 835                 840

 Gly Thr Leu Gln Tyr Met Ala Pro Glu Ile Ile Asp Lys Gly Pro
                 845                 850                 855

 Arg Gly Tyr Gly Lys Ala Ala Asp Ile Trp Ser Leu Gly Cys Thr
                 860                 865                 870

 Ile Ile Glu Met Ala Thr Gly Lys Pro Pro Phe Tyr Glu Leu Gly
                 875                 880                 885

 Glu Pro Gln Ala Ala Met Phe Lys Val Gly Met Phe Lys Val His
                 890                 895                 900

 Pro Glu Ile Pro Glu Ser Met Ser Ala Glu Ala Lys Ala Phe Ile
                 905                 910                 915

 Leu Lys Cys Phe Glu Pro Asp Pro Asp Lys Arg Ala Cys Ala Asn
                 920                 925                 930

 Asp Leu Leu Val Asp Glu Phe Leu Lys Val Ser Ser Lys Lys Lys
                 935                 940                 945

 Lys Thr Gln Pro Lys Leu Ser Ala Leu Ser Ala Gly Ser Asn Glu
                 950                 955                 960

 Tyr Leu Arg Ser Ile Ser Leu Pro Val Pro Val Leu Val Glu Asp
                 965                 970                 975

 Thr Ser Ser Ser Ser Glu Tyr Gly Ser Val Ser Pro Asp Thr Glu
                 980                 985                 990

 Leu Lys Val Asp Pro Phe Ser Phe Lys Thr Arg Ala Lys Ser Cys
                 995                1000                1005

 Gly Glu Arg Asp Val Lys Gly Ile Arg Thr Leu Phe Leu Gly Ile
                1010                1015                1020

 Pro Asp Glu Asn Phe Glu Asp His Ser Ala Pro Pro Ser Pro Glu
                1025                1030                1035

 Glu Lys Asp Ser Gly Phe Phe Met Leu Arg Lys Asp Ser Glu Arg
                1040                1045                1050

 Arg Ala Thr Leu His Arg Ile Leu Thr Glu Asp Gln Asp Lys Ile
                1055                1060                1065

 Val Arg Asn Leu Met Glu Ser Leu Ala Gln Gly Ala Glu Glu Pro
                1070                1075                1080

 Lys Leu Lys Trp Glu His Ile Thr Thr Leu Ile Ala Ser Leu Arg
                1085                1090                1095

 Glu Phe Val Arg Ser Thr Asp Arg Lys Ile Ile Ala Thr Thr Leu
                1100                1105                1110

 Ser Lys Leu Lys Leu Glu Leu Asp Phe Asp Ser His Gly Ile Ser
                1115                1120                1125

 Gln Val Gln Val Val Leu Phe Gly Phe Gln Asp Ala Val Asn Lys
                1130                1135                1140

 Val Leu Arg Asn His Asn Ile Lys Pro His Trp Met Phe Ala Leu
                1145                1150                1155

 Asp Ser Ile Ile Arg Lys Ala Val Gln Thr Ala Ile Thr Ile Leu
                1160                1165                1170

 Val Pro Glu Leu Arg Pro His Phe Ser Leu Ala Ser Glu Ser Asp
                1175                1180                1185

 Thr Ala Asp Gln Glu Asp Leu Asp Val Glu Asp Asp His Glu Glu
                1190                1195                1200

 Gln Pro Ser Asn Gln Thr Val Arg Arg Pro Gln Ala Val Ile Glu
                1205                1210                1215

 Asp Ala Val Ala Thr Ser Gly Val Ser Thr Leu Ser Ser Thr Val
                1220                1225                1230

 Ser His Asp Ser Gln Ser Ala His Arg Ser Leu Asn Val Gln Leu
                1235                1240                1245

 Gly Arg Met Lys Ile Glu Thr Asn Arg Leu Leu Glu Glu Leu Val
                1250                1255                1260

 Arg Lys Glu Lys Glu Leu Gln Ala Leu Leu His Arg Ala Ile Glu
                1265                1270                1275

 Glu Lys Asp Gln Glu Ile Lys His Leu Lys Leu Lys Ser Gln Pro
                1280                1285                1290

 Ile Glu Ile Pro Glu Leu Pro Val Phe His Leu Asn Ser Ser Gly
                1295                1300                1305

 Thr Asn Thr Glu Asp Ser Glu Leu Thr Asp Trp Leu Arg Val Asn
                1310                1315                1320

 Gly Ala Asp Glu Asp Thr Ile Ser Arg Phe Leu Ala Glu Asp Tyr
                1325                1330                1335

 Thr Leu Leu Asp Val Leu Tyr Tyr Val Thr Arg Asp Asp Leu Lys
                1340                1345                1350

 Cys Leu Arg Leu Arg Gly Gly Met Leu Cys Thr Leu Trp Lys Ala
                1355                1360                1365

 Ile Ile Asp Phe Arg Asn Lys Gln Thr
                1370

<210> 999
<211> 3791
<212> DNA
<213> Homo sapien

<400> 999
 gcggcgacgg agcggggccg gccgtggggc gggcggggag ggaggaggcg 50

 gtgaaggcgg cgggccgggg gggaagatgc cgctggcgca gctggcggac 100

 ccgtggcaga agatggctgt ggagagcccg tccgacagcg ctgagaatgg 150

 acagcaaatt atggatgaac ctatgggaga ggaggagatt aacccacaaa 200

 ctgaagaagt cagtatcaaa gaaattgcaa tcacacatca tgtaaaggaa 250

 ggacatgaaa aggcagatcc ttcccagttt gaacttttaa aagtattagg 300

 gcagggatca tttggaaagg ttttcttagt taaaaaaatc tcaggctctg 350

 atgctaggca gctttatgcc atgaaggtat tgaagaaggc cacactgaaa 400

 gttcgagacc gagttcggac aaaaatggaa cgtgatatct tggtagaggt 450

 taatcatcct tttattgtca agttgcatta tgcttttcaa actgaaggga 500

 agttgtatct tattttggat tttctcaggg gaggagattt gtttacacgc 550

 ttatccaaag aggtgatgtt cacagaagaa gatgtcaaat tctacttggc 600

 tgaacttgca cttgctttag accatctaca tagcctggga ataatttata 650

 gagacttaaa accagaaaat atacttcttg atgaagaagg tcacatcaag 700

 ttaacagatt tcggcctaag taaagagtct attgaccatg aaaagaaggc 750

 atattctttt tgtggaactg tggagtatat ggctccagaa gtagttaatc 800

 gtcgaggtca tactcagagt gctgactggt ggtcttttgg tgtgttaatg 850

 tttgaaatgc ttactggtac actccctttc caaggaaaag atcgaaaaga 900

 aacaatgact atgattctta aagccaaact tggaatgcca cagtttttga 950

 gtcctgaagc gcagagtctt ttacgaatgc ttttcaagcg aaatcctgca 1000

 aacagattag gtgcaggacc agatggagtt gaagaaatta aaagacattc 1050

 atttttctca acgatagact ggaataaact gtatagaaga gaaattcatc 1100

 cgccatttaa acctgcaacg ggcaggcctg aagatacatt ctattttgat 1150

 cctgagttta ctgcaaaaac tcccaaagat tcacctggca ttccacctag 1200

 tgctaatgca catcagcttt ttcgggggtt tagttttgtt gctattacct 1250

 cagatgatga aagccaagct atgcagacag ttggtgtaca ttcaattgtt 1300

 cagcagttac acaggaacag tattcagttt actgatggat atgaagtaaa 1350

 agaagatatt ggagttggct cctactctgt ttgcaagaga tgtatacata 1400

 aagctacaaa catggagttt gcagtgaaga ttattgataa aagcaagaga 1450

 gacccaacag aagaaattga aattcttctt cgttatggac agcatccaaa 1500

 cattatcact ctaaaggatg tatatgatga tggaaagtat gtgtatgtag 1550

 taacagaact tatgaaagga ggtgaattgc tggataaaat tcttagacaa 1600

 aaatttttct ctgaacgaga ggccagtgct gtcctgttca ctataactaa 1650

 aaccgttgaa tatcttcacg cacaaggggt ggttcataga gacttgaaac 1700

 ctagcaacat tctttatgtg gatgaatctg gtaatccgga atctattcga 1750

 atttgtgatt ttggctttgc aaaacagctg agagcggaaa atggtcttct 1800

 catgactcct tgttacactg caaattttgt tgcaccagag gttttaaaaa 1850

 gacaaggcta tgatgctgct tgtgatatat ggagtcttgg tgtcctactc 1900

 tatacaatgc ttaccggtta cactccattt gcaaatggtc ctgatgatac 1950

 accagaggaa atattggcac gaataggtag cggaaaattc tcactcagtg 2000

 gtggttactg gaattctgtt tcagacacag caaaggacct ggtgtcaaag 2050

 atgcttcatg tagaccctca tcagagactg actgctgctc ttgtgctcag 2100

 acatccttgg atcgtccact gggaccaact gccacaatac caactaaaca 2150

 gacaggatgc accacatcta gtaaagggtg ccatggcagc tacatattct 2200

 gctttgaacc gtaatcagtc accagttttg gaaccagtag gccgctctac 2250

 tcttgctcag cggagaggta ttaaaaaaat cacctcaaca gccctgtgaa 2300

 gtgacctcag tgagatattt ggtaccatgg tgtaagctga tagcacaagt 2350

 tctggcgaca ggtagcacgt atctgagaga cacctgcaag cacacactgt 2400

 cccagctggt acccataatg ctgctgttcc tgctgctgct cctgctttcc 2450

 tctcttctcg ctttaaatga ttgttagcaa gttagatttt cctggagctt 2500

 cggaagaaat gaaaatggaa acatgatgaa gatatagtca ctgaatcaat 2550

 gagaaaaata atgaacatat gaataccacc taaaaataca ctgaataaag 2600

 tacaccatat agcattattt ttataggaaa tatttcatgt cccttaaata 2650

 ttctttgtta gttataggga tggacagttt atgttaagca cttagcttaa 2700

 acaatccgtt tatattagca ctgtatccct tgtgccatcc aacattttgt 2750

 atgtttttgt aaacagttca tatacagtac atttctgtac tgctttcttt 2800

 aatgtataca tgccttgttt aacttggaat ctattattat taatcaattg 2850

 actattaaat ctggttaaat agttcacctg gattaacagt attgttggac 2900

 agtcctaaaa atggccagat tgtggaacag ctgttgaatg taatacttcc 2950

 aaaatgtaca tatctttccc cacgtctgtt tcactggttc gttcatttgt 3000

 ttgtttctta aagtcaggtg ctctgtcaga ctaacctaga gagctgttat 3050

 ggtagagaaa gttatcatat gtgtgtggca tgaaatcaag aatacaccta 3100

 tgaagttagt ccatatactt tgcaactcct tagagtactt ttttccttaa 3150

 ttaaggaagt agtccttgca cttctaatct tacatagcat ccatacttag 3200

 aatttggcat atcatctggg attttgccaa tatacgtcaa agccctttaa 3250

 gagtcatggt aaggagatgg gtgaaggaaa atttagcaac aggtaattga 3300

 agtcctattg gatatttcat gtttaaatag atattctata ttaaacacta 3350

 atttaaatgt aataaaggcc aaaggcctct gtatgaaatt ggatttaaac 3400

 tttcttattt tagggaataa aacattattg atcaaacagt atctgttcta 3450

 acctaaaatt ataggtaggg caggctaagt gaacagcatt gagtattttc 3500

 tgaatccctc atgataattt atagccacat actgcttcct ttgacttcag 3550

 gaatgatcag ttttcataat ggccactggg cctgcttaga ttgcagtatt 3600

 cattatctgc atctaatttg gtagtttcca caatcgtatt tgatgaaaga 3650

 aacttcagtc cccattatta cctgtgtctt tgccaagctg cctagcatac 3700

 atcagtatgt aatgtaaaag acatatgagc aagaaaaaag tgatttaact 3750

 tacctcatca agaatgtgcc cctacaggcc gggcgcggtc g 3791

<210> 1000
<211> 765
<212> PRT
<213> Homo sapien

<400> 1000
 Arg Arg Arg Ser Gly Ala Gly Arg Gly Ala Gly Gly Glu Gly Gly
   1               5                  10                  15

 Gly Gly Glu Gly Gly Gly Pro Gly Gly Lys Met Pro Leu Ala Gln
                  20                  25                  30

 Leu Ala Asp Pro Trp Gln Lys Met Ala Val Glu Ser Pro Ser Asp
                  35                  40                  45

 Ser Ala Glu Asn Gly Gln Gln Ile Met Asp Glu Pro Met Gly Glu
                  50                  55                  60

 Glu Glu Ile Asn Pro Gln Thr Glu Glu Val Ser Ile Lys Glu Ile
                  65                  70                  75

 Ala Ile Thr His His Val Lys Glu Gly His Glu Lys Ala Asp Pro
                  80                  85                  90

 Ser Gln Phe Glu Leu Leu Lys Val Leu Gly Gln Gly Ser Phe Gly
                  95                 100                 105

 Lys Val Phe Leu Val Lys Lys Ile Ser Gly Ser Asp Ala Arg Gln
                 110                 115                 120

 Leu Tyr Ala Met Lys Val Leu Lys Lys Ala Thr Leu Lys Val Arg
                 125                 130                 135

 Asp Arg Val Arg Thr Lys Met Glu Arg Asp Ile Leu Val Glu Val
                 140                 145                 150

 Asn His Pro Phe Ile Val Lys Leu His Tyr Ala Phe Gln Thr Glu
                 155                 160                 165

 Gly Lys Leu Tyr Leu Ile Leu Asp Phe Leu Arg Gly Gly Asp Leu
                 170                 175                 180

 Phe Thr Arg Leu Ser Lys Glu Val Met Phe Thr Glu Glu Asp Val
                 185                 190                 195

 Lys Phe Tyr Leu Ala Glu Leu Ala Leu Ala Leu Asp His Leu His
                 200                 205                 210

 Ser Leu Gly Ile Ile Tyr Arg Asp Leu Lys Pro Glu Asn Ile Leu
                 215                 220                 225

 Leu Asp Glu Glu Gly His Ile Lys Leu Thr Asp Phe Gly Leu Ser
                 230                 235                 240

 Lys Glu Ser Ile Asp His Glu Lys Lys Ala Tyr Ser Phe Cys Gly
                 245                 250                 255

 Thr Val Glu Tyr Met Ala Pro Glu Val Val Asn Arg Arg Gly His
                 260                 265                 270

 Thr Gln Ser Ala Asp Trp Trp Ser Phe Gly Val Leu Met Phe Glu
                 275                 280                 285

 Met Leu Thr Gly Thr Leu Pro Phe Gln Gly Lys Asp Arg Lys Glu
                 290                 295                 300

 Thr Met Thr Met Ile Leu Lys Ala Lys Leu Gly Met Pro Gln Phe
                 305                 310                 315

 Leu Ser Pro Glu Ala Gln Ser Leu Leu Arg Met Leu Phe Lys Arg
                 320                 325                 330

 Asn Pro Ala Asn Arg Leu Gly Ala Gly Pro Asp Gly Val Glu Glu
                 335                 340                 345

 Ile Lys Arg His Ser Phe Phe Ser Thr Ile Asp Trp Asn Lys Leu
                 350                 355                 360

 Tyr Arg Arg Glu Ile His Pro Pro Phe Lys Pro Ala Thr Gly Arg
                 365                 370                 375

 Pro Glu Asp Thr Phe Tyr Phe Asp Pro Glu Phe Thr Ala Lys Thr
                 380                 385                 390

 Pro Lys Asp Ser Pro Gly Ile Pro Pro Ser Ala Asn Ala His Gln
                 395                 400                 405

 Leu Phe Arg Gly Phe Ser Phe Val Ala Ile Thr Ser Asp Asp Glu
                 410                 415                 420

 Ser Gln Ala Met Gln Thr Val Gly Val His Ser Ile Val Gln Gln
                 425                 430                 435

 Leu His Arg Asn Ser Ile Gln Phe Thr Asp Gly Tyr Glu Val Lys
                 440                 445                 450

 Glu Asp Ile Gly Val Gly Ser Tyr Ser Val Cys Lys Arg Cys Ile
                 455                 460                 465

 His Lys Ala Thr Asn Met Glu Phe Ala Val Lys Ile Ile Asp Lys
                 470                 475                 480

 Ser Lys Arg Asp Pro Thr Glu Glu Ile Glu Ile Leu Leu Arg Tyr
                 485                 490                 495

 Gly Gln His Pro Asn Ile Ile Thr Leu Lys Asp Val Tyr Asp Asp
                 500                 505                 510

 Gly Lys Tyr Val Tyr Val Val Thr Glu Leu Met Lys Gly Gly Glu
                 515                 520                 525

 Leu Leu Asp Lys Ile Leu Arg Gln Lys Phe Phe Ser Glu Arg Glu
                 530                 535                 540

 Ala Ser Ala Val Leu Phe Thr Ile Thr Lys Thr Val Glu Tyr Leu
                 545                 550                 555

 His Ala Gln Gly Val Val His Arg Asp Leu Lys Pro Ser Asn Ile
                 560                 565                 570

 Leu Tyr Val Asp Glu Ser Gly Asn Pro Glu Ser Ile Arg Ile Cys
                 575                 580                 585

 Asp Phe Gly Phe Ala Lys Gln Leu Arg Ala Glu Asn Gly Leu Leu
                 590                 595                 600

 Met Thr Pro Cys Tyr Thr Ala Asn Phe Val Ala Pro Glu Val Leu
                 605                 610                 615

 Lys Arg Gln Gly Tyr Asp Ala Ala Cys Asp Ile Trp Ser Leu Gly
                 620                 625                 630

 Val Leu Leu Tyr Thr Met Leu Thr Gly Tyr Thr Pro Phe Ala Asn
                 635                 640                 645

 Gly Pro Asp Asp Thr Pro Glu Glu Ile Leu Ala Arg Ile Gly Ser
                 650                 655                 660

 Gly Lys Phe Ser Leu Ser Gly Gly Tyr Trp Asn Ser Val Ser Asp
                 665                 670                 675

 Thr Ala Lys Asp Leu Val Ser Lys Met Leu His Val Asp Pro His
                 680                 685                 690

 Gln Arg Leu Thr Ala Ala Leu Val Leu Arg His Pro Trp Ile Val
                 695                 700                 705

 His Trp Asp Gln Leu Pro Gln Tyr Gln Leu Asn Arg Gln Asp Ala
                 710                 715                 720

 Pro His Leu Val Lys Gly Ala Met Ala Ala Thr Tyr Ser Ala Leu
                 725                 730                 735

 Asn Arg Asn Gln Ser Pro Val Leu Glu Pro Val Gly Arg Ser Thr
                 740                 745                 750

 Leu Ala Gln Arg Arg Gly Ile Lys Lys Ile Thr Ser Thr Ala Leu
                 755                 760                 765

<210> 1001
<211> 6007
<212> DNA
<213> Homo sapien

<400> 1001
 atgagcggcg gcggcgacgt ggtgtgcacc ggctggctga ggaaatcgcc 50

 tcccgagaag aagttgaggc gctatgcctg gaagaaacgc tggtttatcc 100

 tgcggagtgg ccggatgagc ggtgacccag atgttctgga atactacaag 150

 aacgatcact ccaagaagcc tctgcggatc atcaacctga acttctgtga 200

 gcaggtagat gcaggcctga cctttaacaa gaaggagctg caggatagtt 250

 ttgtgtttga catcaagacc agtgaacgca ccttttacct ggtggctgag 300

 acagaagagg acatgaataa gtgggtccag agcatctgcc agatctgtgg 350

 cttcaatcag gctgaggaga gcacagactc cctgagaaat gtttcctcag 400

 ccggtcatgg cccccgctct tctccagctg agctcagcag ctctagccag 450

 caccttctcc gagagcgcaa gtcctcagcc ccatcacact ccagccagcc 500

 aactctgttc acgtttgaac cccctgtgtc aaaccacatg cagcccacct 550

 tgtccaccag cgcacctcag gagtatctct acttgcacca gtgcataagc 600

 cgaagagcag aaaatgcaag gagtgccagc ttctctcagg gcaccagagc 650

 ctcttttctc atgaggagtg acacagctgt acaaaaactt gcccagggca 700

 atggacactg tgtcaacggg atcagtggtc aagtccatgg cttctatagc 750

 cttcccaagc cgagccggca caatacagaa ttcagagaca gtacctacga 800

 cctcccccgc agcctggcct cccatggcca caccaagggc agcctcacag 850

 gctccgagac agataatgag gatgtgtaca ccttcaagac gcccagcaac 900

 accctgtgca gggagttcgg ggacctcctg gtagacaata tggatgttcc 950

 ggccacccca ctctcagcct accagatccc taggacattc actctggaca 1000

 aaaaccacaa tgccatgaca gtggccactc ctggggactc agccatagct 1050

 cccccacccc gcccccccaa gccaagtcag gcagaaacac ctcgatgggg 1100

 cagtcctcag cagagaccgc caatcagtga aaatagcaga tctgtcgctg 1150

 ccaccatccc cagacgcaac accctccctg caatggacaa cagccgactt 1200

 caccgagctt cttcctgtga gacctacgag tacccacagc gtggtggaga 1250

 gagtgcaggc cggtctgctg aatccatgag tgatggagtt ggctctttcc 1300

 tgccagggaa aatgattgtg ggccgatcgg acagcaccaa ttctgaagac 1350

 aactatgtgc ccatgaatcc aggttcttcc accctgttgg ccatggaacg 1400

 agcaggtgat aattcccaga gcgtctacat cccaatgagc ccaggggccc 1450

 atcactttga ctcacttggc tacccatcaa caacccttcc tgtgcaccga 1500

 ggccccagca gaggaagtga gattcagcca ccccctgtca accgcaacct 1550

 caaacctgat cggaaagcaa agccaacacc acttgacctg aggaacaaca 1600

 ccgtcatcga tgaactcccc ttcaagtcac ctatcaccaa gtcttggtct 1650

 agggccaacc acaccttcaa ctccagctcc tcccagtact gccgccccat 1700

 ctccacccag agcatcacca gcacagactc aggagacagc gaagagaact 1750

 atgtccctat gcaaaaccca gtgtctgcat ctcccgttcc cagtggcacg 1800

 aacagtcctg cccctaagaa gagcaccggc agcgttgatt atctggccct 1850

 ggacttccag ccgagctccc caagccccca ccgcaagcca tctacttcat 1900

 ccgtcacctc tgatgagaag gtggactacg ttcaggtgga caaggagaag 1950

 acccaggccc tgcagaacac catgcaggag tggacagacg tgcggcagtc 2000

 ctcagagcct tccaagggtg ccaagctgtg atgagagggc caccgcagag 2050

 cccaggaggc agcatctcca gagctggccc ttcccatctc ccctctcccc 2100

 tctcccgttc ttcctcccat ccacctcctc tctactctgc cagtctcagc 2150

 cttcaaagca cttgacatca gggaccctga acccttcccc tgggaggtga 2200

 gggcctgatc aaggcacctc ctctgcccac tcggggccca gctgtgattt 2250

 ttatcagtaa tggccatgcc tccacccacc ttagttagga gctacttcca 2300

 aaaagcatcc ttcagcctct tcctgtcctt tagacctgac tctctaccag 2350

 atgtttggag ggaagggctg gggctctgag ccagattcca cacctcacgt 2400

 tcagtcacag ccctcagcta tcttccctcc ggccactggg ctacctctcc 2450

 ttcagtccca gaagacaagt ctcaccaacc cagggagtca aggaccagca 2500

 aaccaaagtg gataatggac tttttcattc ctgtttttct tggcaggaga 2550

 gaagcaaggc cactaaaaga ggagatggtg gagacggagg ctcagcagtg 2600

 gtcttgaggg gtaaaggact tagatgccca gatgaagagg gaaagctgac 2650

 atctgcaggg aacccacttt gaggctgagg ccatggcagg acagctgctg 2700

 tggggtgcag aggcagaaga tgaaggacaa aaggaaggga aaactgatgg 2750

 ccaacctaga gcagcaagga gcagggcttg gagctcgggt ggtggagatg 2800

 acaaggacac tgtggggtct gggtccccag aactctggag ctacaggcca 2850

 ctctaggccc aagggctagt cctcttcccc agtcccctca gaggcccccg 2900

 ccagccccac cttgaaagca gcatacaggg gaaggcttgg accaagctgg 2950

 gcgaccaagc acatggggca ggaacacatg gtaaaggggt ggggaatatg 3000

 ggagggagtg tggtgtggat gggggtgatg cagggactga ggggaaccct 3050

 gggacaggca caggctgggc agaggcacag ggcagtgcag gggactctgc 3100

 agtggggtcg ggaagtgagt ttctttgcag tgagcagtgc agtggaagtc 3150

 gggcacagag gtagcagaca gatgtgaagc agtggtgaag gccatgtagc 3200

 aagtggggaa atacatccaa agggcctggg agttgggggg tgcccaacgc 3250

 aatccttggg ggtgcagggt ggagcagaaa gtgaaggagg gacacgtgca 3300

 agagtggtgt gcatggtggt gtgacatgag gaccgttcct aggatgggac 3350

 agtgggtcag gcaggacaag gagaaagcag ggcagaatga tgcctagagg 3400

 accacatcag gcatggctga cagcttgtgc ccatgggctg tggcgtatgt 3450

 cagatcgcag ggtaggaacg agtctggcct ggtgccggcc cagtgtttcc 3500

 tcagctcatc cgccctctgt tgctccctag cattccagga gccatcttgg 3550

 actctcctcc ccaggtttga aaggccatca gattagcagg gacggggtgt 3600

 agggcatcac ccaaggttcc ttctcttaaa ctaagggtgg gggatctgaa 3650

 tgtttttatg ttgactgttc ttgactaaat tttcaagagt ttcagaagca 3700

 acaggacaga ccagacgttt cattctaccc tggggcgaac agaacttctt 3750

 cctcccaaac aatgacttcc tgccatgttt gatggggaca gctaccactg 3800

 tcctctgccc ccattcccct ttcagctccc atgagcatgc atagttcacc 3850

 agaccaatgg cctagccatt ctctaagtcc catcctggaa gaagttattt 3900

 cttcaagagc tgcacctctc ctcctagcat tagtttagat caactcaagg 3950

 agtatttatt aatggctgct gtctccagtt tctggggtta agcactaagg 4000

 acacaagaat caatcagacc ttctccctga acttaagata gccacaatca 4050

 gaaaaaggac aaggacatga gacagtggtg atggccatca gacagagact 4100

 tcaaatgctg atggagggca gaggaagtac ttagggaggt tggtgtcaga 4150

 ggcaggagtg ggggatcagg gaaggtggat tctaggaaaa gggagtgcct 4200

 gaggtaggcc ttagaagggg atgagtcaga tttttacaga ggaggagggc 4250

 agggcttggg tccagtggag gaagaaggaa ggagaggctt ggaaagcctt 4300

 gtgtcttggg aaaaaaaggc ctttgagcat atgggtccag ccactcagaa 4350

 gtgcaggggc catgccttgg tgttccaata agtgaatgga agcagtggtg 4400

 gtagctacac tgggcagagt tggcagggtg ctggttcact ctgcccagcc 4450

 ctgaatgtgt gccttaaagg ccccctacaa ggggccccat acgacagagc 4500

 ttttaactgg tgccttccct gtacccgcag cagccacaag tgggcccaga 4550

 ctattgcagc ctcccataaa catgtgagca tgttctgagt gtgccatgat 4600

 gtgagtggac ctggctggaa tcttcggaga gcgactgagg tgttcaaatc 4650

 gaatctccca ggaggcttcc ttccagcccc ctattctggt aactaccagg 4700

 aggcttcctt ccagccccct attctggtaa ctaccaaaat ccctcgggtg 4750

 caagtgtagg ggtagagatg gaaggatgag aggtgaaatt gaccttttga 4800

 aagcaaagct ctggctcaca ggccccaaac taccagccgt atctagcata 4850

 tccccaccct ccacccacta cctcctccaa caaaggagtc aactcagttg 4900

 aaaaaactgg tcctttggcc tatccatggg tcaaagtcca cctctcctgg 4950

 gggcctggag aggactgagc ctacggaaag gggatacctt cccactcagc 5000

 actgcttcac acaggccccc tgcctggggc tctccaagga gccttcttca 5050

 cccacttcca gctccacttc tgcaaggtta agtcaagtga gaacgatgag 5100

 aaatagggag atggtgtctc cttaagtcct tgatctgcct gtctgtggaa 5150

 tgggaggttg gattagctgc gctgaggtcc catccacagc tggtgctcag 5200

 ctgcttgaag gggagactcc ctcctctgta acttctttct gggggattgg 5250

 ggtgggcagt acctatcccc agtcccctcc tagcttgact ttagtggttt 5300

 ccaatgtaga agttaacaaa gtatgcccca ttcctgtgac aaaagcacaa 5350

 ccattctgaa gttactggag catgggctca gctcatcctc cctctggccc 5400

 cttctcccat ggggacatct cggcccagca cccctatccc atttccagag 5450

 ttcttccttc cccatctggg ccttcataaa atgcagggga agccagactg 5500

 gtctcaggag cgctaaagcc cttccgtggg gggtcgtctt tctgggacta 5550

 gccctgctgt ttaggacctg ggaccacaat ggggtacctg ccgagggggt 5600

 ccccaagaga tccaggctgt catgtgattt atggtggcat gtgttgtgta 5650

 tttgttggct acttgtgtct tgaaatctag aattatttca cgcagaattg 5700

 tcactgtttg tcaggaagag aaaatgggct agtggaagcc cagtcttgag 5750

 ttcttgtctt gttaccattt aaaattgaca tttaattttc aaatcactgt 5800

 tggtgcctaa tcacttaagt tattaattta ttctgttgta ttcttttttt 5850

 taaattgtaa catatttatc cggtgggtgg gacaggagtg tgttcaagtg 5900

 ggtcatgttt ttgctgtggt gacacatggt acaggcttgg agcttgcagg 5950

 tccctttcta ctgtggtgtt ggagcaggac aataaagtcc actagaaatg 6000

 cacccca 6007

<210> 1002
<211> 676
<212> PRT
<213> Homo sapien

<400> 1002
 Met Ser Gly Gly Gly Asp Val Val Cys Thr Gly Trp Leu Arg Lys
   1               5                  10                  15

 Ser Pro Pro Glu Lys Lys Leu Arg Arg Tyr Ala Trp Lys Lys Arg
                  20                  25                  30

 Trp Phe Ile Leu Arg Ser Gly Arg Met Ser Gly Asp Pro Asp Val
                  35                  40                  45

 Leu Glu Tyr Tyr Lys Asn Asp His Ser Lys Lys Pro Leu Arg Ile
                  50                  55                  60

 Ile Asn Leu Asn Phe Cys Glu Gln Val Asp Ala Gly Leu Thr Phe
                  65                  70                  75

 Asn Lys Lys Glu Leu Gln Asp Ser Phe Val Phe Asp Ile Lys Thr
                  80                  85                  90

 Ser Glu Arg Thr Phe Tyr Leu Val Ala Glu Thr Glu Glu Asp Met
                  95                 100                 105

 Asn Lys Trp Val Gln Ser Ile Cys Gln Ile Cys Gly Phe Asn Gln
                 110                 115                 120

 Ala Glu Glu Ser Thr Asp Ser Leu Arg Asn Val Ser Ser Ala Gly
                 125                 130                 135

 His Gly Pro Arg Ser Ser Pro Ala Glu Leu Ser Ser Ser Ser Gln
                 140                 145                 150

 His Leu Leu Arg Glu Arg Lys Ser Ser Ala Pro Ser His Ser Ser
                 155                 160                 165

 Gln Pro Thr Leu Phe Thr Phe Glu Pro Pro Val Ser Asn His Met
                 170                 175                 180

 Gln Pro Thr Leu Ser Thr Ser Ala Pro Gln Glu Tyr Leu Tyr Leu
                 185                 190                 195

 His Gln Cys Ile Ser Arg Arg Ala Glu Asn Ala Arg Ser Ala Ser
                 200                 205                 210

 Phe Ser Gln Gly Thr Arg Ala Ser Phe Leu Met Arg Ser Asp Thr
                 215                 220                 225

 Ala Val Gln Lys Leu Ala Gln Gly Asn Gly His Cys Val Asn Gly
                 230                 235                 240

 Ile Ser Gly Gln Val His Gly Phe Tyr Ser Leu Pro Lys Pro Ser
                 245                 250                 255

 Arg His Asn Thr Glu Phe Arg Asp Ser Thr Tyr Asp Leu Pro Arg
                 260                 265                 270

 Ser Leu Ala Ser His Gly His Thr Lys Gly Ser Leu Thr Gly Ser
                 275                 280                 285

 Glu Thr Asp Asn Glu Asp Val Tyr Thr Phe Lys Thr Pro Ser Asn
                 290                 295                 300

 Thr Leu Cys Arg Glu Phe Gly Asp Leu Leu Val Asp Asn Met Asp
                 305                 310                 315

 Val Pro Ala Thr Pro Leu Ser Ala Tyr Gln Ile Pro Arg Thr Phe
                 320                 325                 330

 Thr Leu Asp Lys Asn His Asn Ala Met Thr Val Ala Thr Pro Gly
                 335                 340                 345

 Asp Ser Ala Ile Ala Pro Pro Pro Arg Pro Pro Lys Pro Ser Gln
                 350                 355                 360

 Ala Glu Thr Pro Arg Trp Gly Ser Pro Gln Gln Arg Pro Pro Ile
                 365                 370                 375

 Ser Glu Asn Ser Arg Ser Val Ala Ala Thr Ile Pro Arg Arg Asn
                 380                 385                 390

 Thr Leu Pro Ala Met Asp Asn Ser Arg Leu His Arg Ala Ser Ser
                 395                 400                 405

 Cys Glu Thr Tyr Glu Tyr Pro Gln Arg Gly Gly Glu Ser Ala Gly
                 410                 415                 420

 Arg Ser Ala Glu Ser Met Ser Asp Gly Val Gly Ser Phe Leu Pro
                 425                 430                 435

 Gly Lys Met Ile Val Gly Arg Ser Asp Ser Thr Asn Ser Glu Asp
                 440                 445                 450

 Asn Tyr Val Pro Met Asn Pro Gly Ser Ser Thr Leu Leu Ala Met
                 455                 460                 465

 Glu Arg Ala Gly Asp Asn Ser Gln Ser Val Tyr Ile Pro Met Ser
                 470                 475                 480

 Pro Gly Ala His His Phe Asp Ser Leu Gly Tyr Pro Ser Thr Thr
                 485                 490                 495

 Leu Pro Val His Arg Gly Pro Ser Arg Gly Ser Glu Ile Gln Pro
                 500                 505                 510

 Pro Pro Val Asn Arg Asn Leu Lys Pro Asp Arg Lys Ala Lys Pro
                 515                 520                 525

 Thr Pro Leu Asp Leu Arg Asn Asn Thr Val Ile Asp Glu Leu Pro
                 530                 535                 540

 Phe Lys Ser Pro Ile Thr Lys Ser Trp Ser Arg Ala Asn His Thr
                 545                 550                 555

 Phe Asn Ser Ser Ser Ser Gln Tyr Cys Arg Pro Ile Ser Thr Gln
                 560                 565                 570

 Ser Ile Thr Ser Thr Asp Ser Gly Asp Ser Glu Glu Asn Tyr Val
                 575                 580                 585

 Pro Met Gln Asn Pro Val Ser Ala Ser Pro Val Pro Ser Gly Thr
                 590                 595                 600

 Asn Ser Pro Ala Pro Lys Lys Ser Thr Gly Ser Val Asp Tyr Leu
                 605                 610                 615

 Ala Leu Asp Phe Gln Pro Ser Ser Pro Ser Pro His Arg Lys Pro
                 620                 625                 630

 Ser Thr Ser Ser Val Thr Ser Asp Glu Lys Val Asp Tyr Val Gln
                 635                 640                 645

 Val Asp Lys Glu Lys Thr Gln Ala Leu Gln Asn Thr Met Gln Glu
                 650                 655                 660

 Trp Thr Asp Val Arg Gln Ser Ser Glu Pro Ser Lys Gly Ala Lys
                 665                 670                 675

 Leu


<210> 1003
<211> 423
<212> DNA
<213> Homo sapien

<400> 1003
 ccggaagtga ctgcggacga atcggcgttt gccgaggctg gcatagattt 50

 ggctgtctcc gctcatagct gcttttggcg cgaaagatgc cgggtctggt 100

 tgactcaaac cctgccccgc ctgagtctca ggagaagaag ccgctgaagc 150

 cctgctgcgc ttgcccggag accaagaagg cgcgcgatgc gtgtatcatc 200

 gagaaaggag aagaacactg tggacatcta attgaggccc acaaggaatg 250

 catgagagcc ctaggattta aaatatgaaa tggtggtctg ctgtgtgaat 300

 aaataattcc tgaagaatga agaagattaa ttttgggagt tctttgacga 350

 actttgatat gtggaaaaag tatttataat ttattgtaag aagaaagtaa 400

 aatattacta gtggaagatc ttc 423

<210> 1004
<211> 63
<212> PRT
<213> Homo sapien

<400> 1004
 Met Pro Gly Leu Val Asp Ser Asn Pro Ala Pro Pro Glu Ser Gln
   1               5                  10                  15

 Glu Lys Lys Pro Leu Lys Pro Cys Cys Ala Cys Pro Glu Thr Lys
                  20                  25                  30

 Lys Ala Arg Asp Ala Cys Ile Ile Glu Lys Gly Glu Glu His Cys
                  35                  40                  45

 Gly His Leu Ile Glu Ala His Lys Glu Cys Met Arg Ala Leu Gly
                  50                  55                  60

 Phe Lys Ile


<210> 1005
<211> 891
<212> DNA
<213> Homo sapien

<400> 1005
 gcgaggcgcc cgaagccgtc gcggcgggga ccatgttgct tccgaacatc 50

 ctgctcaccg gtacaccagg ggttggaaaa accacactag gcaaagaact 100

 tgcgtcaaaa tcaggactga aatacattaa tgtgggtgat ttagctcgag 150

 aagagcaatt gtatgatggc tatgatgaag agtatgactg tcccatttta 200

 gatgaagaca gagtagttga tgagttagat aaccaaatga gagaaggtgg 250

 agttattgtt gattaccatg gttgtgattt cttccctgaa cgctggtttc 300

 atatagtttt tgtgctgaga acagatacca atgtattgta cgaaagactt 350

 gaaacaaggg gttataatga gaagaaacta acagacaata ttcagtgtga 400

 gatttttcaa gttctttatg aagaagccac agcatcctac aaggaagaaa 450

 tcgtgcatca gctgcccagt aataaaccag aagagctaga aaataatgta 500

 gatcagatct tgaaatggat tgagcagtgg atcaaagatc ataactcttg 550

 acttataagg ctagctactt aataatcact cttgttgata tctctgccga 600

 catcatagaa attgttcaag tgtcagtaac actttattaa aatcatgttg 650

 cagaaccagc aggtggatag tatataggtt tatgcctgtg tttctttttc 700

 tccatgagaa agctaaacat gaaatataat gaatatagta ttattaagga 750

 ttgagacaaa aactgtgatt ttaatactta aattgctaaa gaataaataa 800

 atctgacaaa atgggtggat atcttttaag tttattacag aaaaaaatgc 850

 agatgatctc ttaaaataaa actaaagata aagcaaaaaa a 891

<210> 1006
<211> 172
<212> PRT
<213> Homo sapien

<400> 1006
 Met Leu Leu Pro Asn Ile Leu Leu Thr Gly Thr Pro Gly Val Gly
   1               5                  10                  15

 Lys Thr Thr Leu Gly Lys Glu Leu Ala Ser Lys Ser Gly Leu Lys
                  20                  25                  30

 Tyr Ile Asn Val Gly Asp Leu Ala Arg Glu Glu Gln Leu Tyr Asp
                  35                  40                  45

 Gly Tyr Asp Glu Glu Tyr Asp Cys Pro Ile Leu Asp Glu Asp Arg
                  50                  55                  60

 Val Val Asp Glu Leu Asp Asn Gln Met Arg Glu Gly Gly Val Ile
                  65                  70                  75

 Val Asp Tyr His Gly Cys Asp Phe Phe Pro Glu Arg Trp Phe His
                  80                  85                  90

 Ile Val Phe Val Leu Arg Thr Asp Thr Asn Val Leu Tyr Glu Arg
                  95                 100                 105

 Leu Glu Thr Arg Gly Tyr Asn Glu Lys Lys Leu Thr Asp Asn Ile
                 110                 115                 120

 Gln Cys Glu Ile Phe Gln Val Leu Tyr Glu Glu Ala Thr Ala Ser
                 125                 130                 135

 Tyr Lys Glu Glu Ile Val His Gln Leu Pro Ser Asn Lys Pro Glu
                 140                 145                 150

 Glu Leu Glu Asn Asn Val Asp Gln Ile Leu Lys Trp Ile Glu Gln
                 155                 160                 165

 Trp Ile Lys Asp His Asn Ser
                 170

<210> 1007
<211> 2518
<212> DNA
<213> Homo sapien

<400> 1007
 ccagcagtgg ctgcaccatg cacgtgaacg gcaaagtggc gctggtgacc 50

 ggcgcggctc agggcatagg cagagccttt gcagaggcgc tgctgcttaa 100

 gggcgccaag gtagcgctgg tggattggaa tcttgaagca ggtgtacagt 150

 gtaaagctgc cctgcatgag caatttgaac ctcagaagac tctgttcatc 200

 cagtgcgatg tggctgacca gcaacaactg agagacactt ttagaaaagt 250

 tgtagaccac tttggaagac tggacatttt ggtcaataat gctggagtga 300

 ataatgagaa aaactgggaa aaaactctgc aaattaattt ggtttctgtt 350

 atcagtggaa cctatcttgg tttggattac atgagtaagc aaaatggagg 400

 tgaaggcggc atcattatca atatgtcatc tttagcagga ctcatgcccg 450

 ttgcacagca gccggtttat tgtgcttcaa agcatggcat agttggattc 500

 acacgctcag cagcgttggc tgctaatctt atgaacagtg gtgtgagact 550

 gaatgccatt tgtccaggct ttgttaacac agccatcctt gaatcaattg 600

 aaaaagaaga aaacatggga caatatatag aatataagga tcatatcaag 650

 gatatgatta aatactatgg aattttggac ccaccattga ttgccaatgg 700

 attgataaca ctcattgaag atgatgcttt aaatggtgct attatgaaga 750

 tcacaacttc taagggaatt cattttcaag actatgatac aactccattt 800

 caagcaaaaa cccaatgaac agcttatgtg ttagccatag ctgaaaataa 850

 gcacaaatag cttatattca gatcctatct tcatttgaat atagctttta 900

 aatgaaatgt tacagtttga agttttcctt catgcacttg gtgataaacg 950

 ttttctaaat ttttagttaa gtatatggat aaaaagttat gaactattaa 1000

 aaatgtgatg tggaccaaag gctaggttgt aatcttgata gtctaaaaaa 1050

 tgatcaaaac aaatgatttt caaggaatat tcaatattct gcctttcaga 1100

 aagtgtattt atatctgtgc ttcataaata ttaatgttct tcagaacatc 1150

 attttaaagg agatacttga attgttattt aaatcaaacc agatgtaaaa 1200

 cactcacata caagttcata ctttaaaaga ggaaagctac ttaacaatga 1250

 caaatatttc acaataataa tttttactta tataccatct ttcaactgaa 1300

 catttcagtt cttccaagag cttcttagag tagtatattt tgggggcagt 1350

 caaggaataa actacagtgt aaacatatcc cagatgaaaa ctgctgtatg 1400

 gaaaaatgac agaaagtaac tgattgacac tgttgattca cagttcagcc 1450

 tcctatctgg gaaagacatt tctttcctct gctcacttta agaactttta 1500

 ccgactccaa aaatctcagg aattaaactt ttaacagtta cagcaataaa 1550

 gaatagttag tactccaaaa atattatatt taagatgctc aacaagaaaa 1600

 aaatgcaaat gtaatatttt tttcaaatta cttctttatt gacttgtcca 1650

 aatttcaaaa gtgcctaccc ttcaataaaa cttttttatt ctgatctcca 1700

 taaattactt agtcttctat gtatagctat caaggaaata aaaccaattt 1750

 tgccacagcc acaactgtaa atgtttttgt acccatgctg aaactcataa 1800

 caacacagac ataaaaatag ctgtgaggtt ttgctttttt tgttgtcagc 1850

 tatcttaaga atcattaaat acacctgctt tgggtaaaac tctttgcaag 1900

 cagtaattaa cactagtaac agtgaaagca caagatttcc aaatcagtcg 1950

 ttttctcaaa aaaatatcgt ataagtgact catcctgtct gctaactcca 2000

 gacctcccag cttgaagcca aatctttcca tgtgagattg atatggattt 2050

 cctagaagta ctggaatgtt gtcatatctt gccctatttt aattctgcta 2100

 tagaaaacaa ttgccttcac ttttaaggag taatttgaat attaataact 2150

 ctggtctaga ttttcatata atgtattaaa gacaaagtag tgaacatcaa 2200

 tgaacatctg atagagataa actgtaatca ggcataagct tgtttgtatg 2250

 ttctggcagt gactaatcag taaatgatgt cggtttgccc agtatcactt 2300

 atcttctgta tttttcctct gtcgtgtaaa tagtataacc ttttcattta 2350

 tggacaattt tttggactag tagccttcaa tatacattct gctttgaatt 2400

 aattttttca aatcaataaa ttatgtagac atttaaaatc aaatatcaag 2450

 tagaattgaa aaatgtgagt tacataagtt aaaaacttac tttaaatctt 2500

 accttctata ggtagctc 2518

<210> 1008
<211> 266
<212> PRT
<213> Homo sapien

<400> 1008
 Met His Val Asn Gly Lys Val Ala Leu Val Thr Gly Ala Ala Gln
   1               5                  10                  15

 Gly Ile Gly Arg Ala Phe Ala Glu Ala Leu Leu Leu Lys Gly Ala
                  20                  25                  30

 Lys Val Ala Leu Val Asp Trp Asn Leu Glu Ala Gly Val Gln Cys
                  35                  40                  45

 Lys Ala Ala Leu His Glu Gln Phe Glu Pro Gln Lys Thr Leu Phe
                  50                  55                  60

 Ile Gln Cys Asp Val Ala Asp Gln Gln Gln Leu Arg Asp Thr Phe
                  65                  70                  75

 Arg Lys Val Val Asp His Phe Gly Arg Leu Asp Ile Leu Val Asn
                  80                  85                  90

 Asn Ala Gly Val Asn Asn Glu Lys Asn Trp Glu Lys Thr Leu Gln
                  95                 100                 105

 Ile Asn Leu Val Ser Val Ile Ser Gly Thr Tyr Leu Gly Leu Asp
                 110                 115                 120

 Tyr Met Ser Lys Gln Asn Gly Gly Glu Gly Gly Ile Ile Ile Asn
                 125                 130                 135

 Met Ser Ser Leu Ala Gly Leu Met Pro Val Ala Gln Gln Pro Val
                 140                 145                 150

 Tyr Cys Ala Ser Lys His Gly Ile Val Gly Phe Thr Arg Ser Ala
                 155                 160                 165

 Ala Leu Ala Ala Asn Leu Met Asn Ser Gly Val Arg Leu Asn Ala
                 170                 175                 180

 Ile Cys Pro Gly Phe Val Asn Thr Ala Ile Leu Glu Ser Ile Glu
                 185                 190                 195

 Lys Glu Glu Asn Met Gly Gln Tyr Ile Glu Tyr Lys Asp His Ile
                 200                 205                 210

 Lys Asp Met Ile Lys Tyr Tyr Gly Ile Leu Asp Pro Pro Leu Ile
                 215                 220                 225

 Ala Asn Gly Leu Ile Thr Leu Ile Glu Asp Asp Ala Leu Asn Gly
                 230                 235                 240

 Ala Ile Met Lys Ile Thr Thr Ser Lys Gly Ile His Phe Gln Asp
                 245                 250                 255

 Tyr Asp Thr Thr Pro Phe Gln Ala Lys Thr Gln
                 260                 265

<210> 1009
<211> 2545
<212> DNA
<213> Homo sapien

<400> 1009
 atccaataca ggagtgactt ggaactccat tctatcacta tgaagaaaag 50

 tggtgttctt ttcctcttgg gcatcatctt gctggttctg attggagtgc 100

 aaggaacccc agtagtgaga aagggtcgct gttcctgcat cagcaccaac 150

 caagggacta tccacctaca atccttgaaa gaccttaaac aatttgcccc 200

 aagcccttcc tgcgagaaaa ttgaaatcat tgctacactg aagaatggag 250

 ttcaaacatg tctaaaccca gattcagcag atgtgaagga actgattaaa 300

 aagtgggaga aacaggtcag ccaaaagaaa aagcaaaaga atgggaaaaa 350

 acatcaaaaa aagaaagttc tgaaagttcg aaaatctcaa cgttctcgtc 400

 aaaagaagac tacataagag accacttcac caataagtat tctgtgttaa 450

 aaatgttcta ttttaattat accgctatca ttccaaagga ggatggcata 500

 taatacaaag gcttattaat ttgactagaa aatttaaaac attactctga 550

 aattgtaact aaagttagaa agttgatttt aagaatccaa acgttaagaa 600

 ttgttaaagg ctatgattgt ctttgttctt ctaccaccca ccagttgaat 650

 ttcatcatgc ttaaggccat gattttagca atacccatgt ctacacagat 700

 gttcacccaa ccacatccca ctcacaacag ctgcctggaa gagcagccct 750

 aggcttccac gtactgcagc ctccagagag tatctgaggc acatgtcagc 800

 aagtcctaag cctgttagca tgctggtgag ccaagcagtt tgaaattgag 850

 ctggacctca ccaagctgct gtggccatca acctctgtat ttgaatcagc 900

 ctacaggcct cacacacaat gtgtctgaga gattcatgct gattgttatt 950

 gggtatcacc actggagatc accagtgtgt ggctttcaga gcctcctttc 1000

 tggctttgga agccatgtga ttccatcttg cccgctcagg ctgaccactt 1050

 tatttctttt tgttcccctt tgcttcattc aagtcagctc ttctccatcc 1100

 taccacaatg cagtgccttt cttctctcca gtgcacctgt catatgctct 1150

 gatttatctg agtcaactcc tttctcatct tgtccccaac accccacaga 1200

 agtgctttct tctcccaatt catcctcact cagtccagct tagttcaagt 1250

 cctgcctctt aaataaacct ttttggacac acaaattatc ttaaaactcc 1300

 tgtttcactt ggttcagtac cacatgggtg aacactcaat ggttaactaa 1350

 ttcttgggtg tttatcctat ctctccaacc agattgtcag ctccttgagg 1400

 gcaagagcca cagtatattt ccctgtttct tccacagtgc ctaataatac 1450

 tgtggaacta ggttttaata attttttaat tgatgttgtt atgggcagga 1500

 tggcaaccag accattgtct cagagcaggt gctggctctt tcctggctac 1550

 tccatgttgg ctagcctctg gtaacctctt acttattatc ttcaggacac 1600

 tcactacagg gaccagggat gatgcaacat ccttgtcttt ttatgacagg 1650

 atgtttgctc agcttctcca acaataagaa gcacgtggta aaacacttgc 1700

 ggatattctg gactgttttt aaaaaatata cagtttaccg aaaatcatat 1750

 aatcttacaa tgaaaaggac tttatagatc agccagtgac caaccttttc 1800

 ccaaccatac aaaaattcct tttcccgaag gaaaagggct ttctcaataa 1850

 gcctcagctt tctaagatct aacaagatag ccaccgagat ccttatcgaa 1900

 actcatttta ggcaaatatg agttttattg tccgtttact tgtttcagag 1950

 tttgtattgt gattatcaat taccacacca tctcccatga agaaagggaa 2000

 cggtgaagta ctaagcgcta gaggaagcag ccaagtcggt tagtggaagc 2050

 atgattggtg cccagttagc ctctgcagga tgtggaaacc tccttccagg 2100

 ggaggttcag tgaattgtgt aggagaggtt gtctgtggcc agaatttaaa 2150

 cctatactca ctttcccaaa ttgaatcact gctcacactg ctgatgattt 2200

 agagtgctgt ccggtggaga tcccacccga acgtcttatc taatcatgaa 2250

 actccctagt tccttcatgt aacttccctg aaaaatctaa gtgtttcata 2300

 aatttgagag tctgtgaccc acttaccttg catctcacag gtagacagta 2350

 tataactaac aaccaaagac tacatattgt cactgacaca cacgttataa 2400

 tcatttatca tatatataca tacatgcata cactctcaaa gcaaataatt 2450

 tttcacttca aaacagtatt gacttgtata ccttgtaatt tgaaatattt 2500

 tctttgttaa aatagaatgg tatcaataaa tagaccatta atcag 2545

<210> 1010
<211> 125
<212> PRT
<213> Homo sapien

<400> 1010
 Met Lys Lys Ser Gly Val Leu Phe Leu Leu Gly Ile Ile Leu Leu
   1               5                  10                  15

 Val Leu Ile Gly Val Gln Gly Thr Pro Val Val Arg Lys Gly Arg
                  20                  25                  30

 Cys Ser Cys Ile Ser Thr Asn Gln Gly Thr Ile His Leu Gln Ser
                  35                  40                  45

 Leu Lys Asp Leu Lys Gln Phe Ala Pro Ser Pro Ser Cys Glu Lys
                  50                  55                  60

 Ile Glu Ile Ile Ala Thr Leu Lys Asn Gly Val Gln Thr Cys Leu
                  65                  70                  75

 Asn Pro Asp Ser Ala Asp Val Lys Glu Leu Ile Lys Lys Trp Glu
                  80                  85                  90

 Lys Gln Val Ser Gln Lys Lys Lys Gln Lys Asn Gly Lys Lys His
                  95                 100                 105

 Gln Lys Lys Lys Val Leu Lys Val Arg Lys Ser Gln Arg Ser Arg
                 110                 115                 120

 Gln Lys Lys Thr Thr
                 125

<210> 1011
<211> 2404
<212> DNA
<213> Homo sapien

<400> 1011
 cgaggaacga gtgacagccg gacagtccgc cgggcggtga tccggggccg 50

 ctcccgggcg cgccctcggc tccaggtcct acccggagcc gctgccatgg 100

 gagagccagc cttgggcgct ggggaccagc cgccgcgccc gcctcggagt 150

 cgcggcccga gtcccggcgc cagcagccag cccgctgcgt ccccttcccg 200

 ggctgcaggg ctgcctccgc cgcgccgccg gcccggattg tgcctgtgat 250

 gagccgcagc ccgcagcgag ctctgccccc gggcgcgctc cctcggctgc 300

 tccaggctgc gcctgcagcc gcgccgcgtg ccctgctccc gcagtggccc 350

 cggcgcccag gacgccgctg gcccgcgtcc cctctcggaa tgaaggtgtt 400

 ccgtaggaag gcgctggtgt tgtgcgcggg ctatgcactg ctgctggtgc 450

 tcactatgct caacctcctg gactacaagt ggcacaagga gccgctgcag 500

 cagtgcaacc ccgatgggcc gctgggtgcc gcagcggggg cagccggagg 550

 cagctggggg cgcccagggc cgcctccggc cgggccgccc cgtgctcatg 600

 cccgtttgga cctccgcact ccttaccgcc ctcccgctgc cgccgtcggg 650

 gcggctcctg cagccgcggc agggatggcg ggggttgcgg cccctccagg 700

 caatggcact cggggcaccg ggggcgtcgg ggacaagcgg cagctggtgt 750

 acgtgttcac cacgtggcgc tctggctcgt cgttcttcgg cgagctattc 800

 aaccagaatc ccgaggtgtt ctttctctac gagccagtgt ggcatgtatg 850

 gcaaaaactg tatccggggg acgccgtttc cctgcagggg gcagcgcggg 900

 acatgctgag cgctctttac cgctgcgacc tctctgtctt ccagttgtat 950

 agccccgcgg gcagcggggg gcgcaacctc accacgctgg gcatcttcgg 1000

 cgcagccacc aacaaggtgg tgtgctcgtc accactctgc cccgcctacc 1050

 gcaaggaggt cgtggggttg gtggacgacc gcgtgtgcaa gaagtgcccg 1100

 ccacagcgcc tggcgcgttt cgaggaggag tgccgcaagt accgcacact 1150

 agtcataaag ggtgtgcgcg tcttcgacgt ggcggtcttg gcgccactgc 1200

 tgcgagaccc ggccctggac ctcaaggtca tccacttggt gcgtgatccc 1250

 cgcgcggtgg cgagttcacg gatccgctcg cgccacggcc tcatccgtga 1300

 gagcctacag gtggtgcgca gccgagaccc gcgagctcac cgcatgccct 1350

 tcttggaggc cgcgggccac aagcttggcg ccaagaagga gggcgtgggc 1400

 ggccccgcag actaccacgc tctgggcgct atggaggtca tctgcaatag 1450

 tatggctaag acgctgcaga cagccctgca gccccctgac tggctgcagg 1500

 gccactacct ggtggtgcgg tacgaggacc tggtgggaga ccccgtcaag 1550

 acactacgga gagtgtacga ttttgtggga ctgttggtga gccccgaaat 1600

 ggagcagttt gccctgaaca tgaccagtgg ctcgggctcc tcctccaagc 1650

 ctttcgtggt atctgcacgc aatgccacgc aggccgccaa tgcctggcgg 1700

 accgccctca ccttccagca gatcaaacag gtggaggagt tttgctacca 1750

 gcccatggcc gtcctgggct atgagcgggt caacagccct gaggaggtca 1800

 aagacctcag caagaccctg cttcggaagc cccgtctcta aaaggggttc 1850

 ccaggagacc tgattccctg tggtgatacc tataaagagg atcgtagtgt 1900

 gtttaaataa acacagtcca gactcaaacg gaggaagccc acatattcta 1950

 ttatagatat ataaataatc acacacacac ttgctgtcaa tgttttgagt 2000

 cagtgcattt caaggaacag ccacaaaata cacaccccta agaaaaggca 2050

 agacttgaac gttctgacca ggtgcccctc ttcttctttg ccttctcttg 2100

 tcctctttct cctatttctt accctgtcct ccacctgcct tccattttga 2150

 agtgggatgt taatgaaatc aagttccagt aacccaaatc ttgtttacaa 2200

 aatattcgtg gtatctgtga acatgttaag agtaatttgg atgtgggggt 2250

 gggggtggag aaaggggaag tggtccagaa acaaaaagcc ccattgggca 2300

 tgataagccg aggaggcatt cttctaaagc agacttttgt gtaaaaagca 2350

 aaggttacat gtgagtatta ataaagaaga taataaataa aaaaaaaaaa 2400

 aaaa 2404

<210> 1012
<211> 530
<212> PRT
<213> Homo sapien

<400> 1012
 Met Ser Arg Ser Pro Gln Arg Ala Leu Pro Pro Gly Ala Leu Pro
   1               5                  10                  15

 Arg Leu Leu Gln Ala Ala Pro Ala Ala Ala Pro Arg Ala Leu Leu
                  20                  25                  30

 Pro Gln Trp Pro Arg Arg Pro Gly Arg Arg Trp Pro Ala Ser Pro
                  35                  40                  45

 Leu Gly Met Lys Val Phe Arg Arg Lys Ala Leu Val Leu Cys Ala
                  50                  55                  60

 Gly Tyr Ala Leu Leu Leu Val Leu Thr Met Leu Asn Leu Leu Asp
                  65                  70                  75

 Tyr Lys Trp His Lys Glu Pro Leu Gln Gln Cys Asn Pro Asp Gly
                  80                  85                  90

 Pro Leu Gly Ala Ala Ala Gly Ala Ala Gly Gly Ser Trp Gly Arg
                  95                 100                 105

 Pro Gly Pro Pro Pro Ala Gly Pro Pro Arg Ala His Ala Arg Leu
                 110                 115                 120

 Asp Leu Arg Thr Pro Tyr Arg Pro Pro Ala Ala Ala Val Gly Ala
                 125                 130                 135

 Ala Pro Ala Ala Ala Ala Gly Met Ala Gly Val Ala Ala Pro Pro
                 140                 145                 150

 Gly Asn Gly Thr Arg Gly Thr Gly Gly Val Gly Asp Lys Arg Gln
                 155                 160                 165

 Leu Val Tyr Val Phe Thr Thr Trp Arg Ser Gly Ser Ser Phe Phe
                 170                 175                 180

 Gly Glu Leu Phe Asn Gln Asn Pro Glu Val Phe Phe Leu Tyr Glu
                 185                 190                 195

 Pro Val Trp His Val Trp Gln Lys Leu Tyr Pro Gly Asp Ala Val
                 200                 205                 210

 Ser Leu Gln Gly Ala Ala Arg Asp Met Leu Ser Ala Leu Tyr Arg
                 215                 220                 225

 Cys Asp Leu Ser Val Phe Gln Leu Tyr Ser Pro Ala Gly Ser Gly
                 230                 235                 240

 Gly Arg Asn Leu Thr Thr Leu Gly Ile Phe Gly Ala Ala Thr Asn
                 245                 250                 255

 Lys Val Val Cys Ser Ser Pro Leu Cys Pro Ala Tyr Arg Lys Glu
                 260                 265                 270

 Val Val Gly Leu Val Asp Asp Arg Val Cys Lys Lys Cys Pro Pro
                 275                 280                 285

 Gln Arg Leu Ala Arg Phe Glu Glu Glu Cys Arg Lys Tyr Arg Thr
                 290                 295                 300

 Leu Val Ile Lys Gly Val Arg Val Phe Asp Val Ala Val Leu Ala
                 305                 310                 315

 Pro Leu Leu Arg Asp Pro Ala Leu Asp Leu Lys Val Ile His Leu
                 320                 325                 330

 Val Arg Asp Pro Arg Ala Val Ala Ser Ser Arg Ile Arg Ser Arg
                 335                 340                 345

 His Gly Leu Ile Arg Glu Ser Leu Gln Val Val Arg Ser Arg Asp
                 350                 355                 360

 Pro Arg Ala His Arg Met Pro Phe Leu Glu Ala Ala Gly His Lys
                 365                 370                 375

 Leu Gly Ala Lys Lys Glu Gly Val Gly Gly Pro Ala Asp Tyr His
                 380                 385                 390

 Ala Leu Gly Ala Met Glu Val Ile Cys Asn Ser Met Ala Lys Thr
                 395                 400                 405

 Leu Gln Thr Ala Leu Gln Pro Pro Asp Trp Leu Gln Gly His Tyr
                 410                 415                 420

 Leu Val Val Arg Tyr Glu Asp Leu Val Gly Asp Pro Val Lys Thr
                 425                 430                 435

 Leu Arg Arg Val Tyr Asp Phe Val Gly Leu Leu Val Ser Pro Glu
                 440                 445                 450

 Met Glu Gln Phe Ala Leu Asn Met Thr Ser Gly Ser Gly Ser Ser
                 455                 460                 465

 Ser Lys Pro Phe Val Val Ser Ala Arg Asn Ala Thr Gln Ala Ala
                 470                 475                 480

 Asn Ala Trp Arg Thr Ala Leu Thr Phe Gln Gln Ile Lys Gln Val
                 485                 490                 495

 Glu Glu Phe Cys Tyr Gln Pro Met Ala Val Leu Gly Tyr Glu Arg
                 500                 505                 510

 Val Asn Ser Pro Glu Glu Val Lys Asp Leu Ser Lys Thr Leu Leu
                 515                 520                 525

 Arg Lys Pro Arg Leu
                 530

<210> 1013
<211> 1610
<212> DNA
<213> Homo sapien

<400> 1013
 ggcacgaggc tgcggccgca gtagccggag ccggagccgc agccaccggt 50

 gccttccttt cccgccgccg cccagccgcc gtccggcctc cctcgggccc 100

 gagcgcagac caggctccag ccgcgcggcg ccggcagcct cgcgctccct 150

 ctcgggtctc tctcgggcct cgggcaccgc gtcctgtggg cggccgcctg 200

 cctgcccgcc cgcccgcagc cccttgcctg ccggcccctg ggcggcccgt 250

 gccatgggca ccgacagccg cgcggccaag gcgctcctgg cgcgggcccg 300

 caccctgcac ctgcagacgg ggaacctgct gaactggggc cgcctgcgga 350

 agaagtgccc gtccacgcac agcgaggagc ttcatgattg tatccaaaaa 400

 accttgaatg aatggagttc ccaaatcaac ccagatttgg tcagggagtt 450

 tccagatgtc ttggaatgca ctgtatctca tgcagtagaa aagataaatc 500

 ctgatgaaag agaagaaatg aaagtttctg caaaactgtt cattgtagaa 550

 tcaaactctt catcatcaac tagaagtgca gttgacatgg cctgttcagt 600

 ccttggagtt gcacagctgg attctgtgat cattgcttca cctcctattg 650

 aagatggagt taatctttcc ttggagcatt tacagcctta ctgggaggaa 700

 ttagaaaact tagttcagag caaaaagatt gttgccatag gtacctctga 750

 tctagacaaa acacagttgg aacagctgta tcagtgggca caggtaaaac 800

 caaatagtaa ccaagttaat cttgcctcct gctgtgtgat gccaccagat 850

 ttgactgcat ttgctaaaca atttgacata cagctgttga ctcacaatga 900

 tccaaaagaa ctgctttctg aagcaagttt ccaagaagct cttcaggaaa 950

 gcattcctga cattcaagcg cacgagtggg tgccgctgtg gctactgcgg 1000

 tattcggtca ttgtgaaaag tagaggaatt atcaaatcaa aaggctacat 1050

 tttacaagct aaaagaaggg gttcttaact gacttaggag cataacttac 1100

 ctgtaatttc cttcaatatg agagaaaatt gagatgtgta aaatctagtt 1150

 actgcctgta aatggtgtca ttgaggcaga tattctttcg tcatatttga 1200

 cagtatgttg tctgtcaagt tttaaatact tatcttgcct ccatatcaat 1250

 ccattctcat gaacctctgt attgctttcc ttaaactatt gttttctaat 1300

 tgaaattgtc tataaagaaa atacttgcaa tatatttttc ctttattttt 1350

 atgactaata taaatcaaga aaatttgttg ttagatatat tttggcctag 1400

 gtatcagggt aatgtatata catatttttt atttccaaaa aaaattcatt 1450

 aattgcttct taactcttat tataaccaag caatttaatt acaattgtta 1500

 aaactgaaat actggaagaa gatatttttc ctgtcattga tgagatatat 1550

 cagagtaact ggagtagctg ggatttacta gtagtgtaaa taaaattcac 1600

 tcttcaatac 1610

<210> 1014
<211> 274
<212> PRT
<213> Homo sapien

<400> 1014
 Met Gly Thr Asp Ser Arg Ala Ala Lys Ala Leu Leu Ala Arg Ala
   1               5                  10                  15

 Arg Thr Leu His Leu Gln Thr Gly Asn Leu Leu Asn Trp Gly Arg
                  20                  25                  30

 Leu Arg Lys Lys Cys Pro Ser Thr His Ser Glu Glu Leu His Asp
                  35                  40                  45

 Cys Ile Gln Lys Thr Leu Asn Glu Trp Ser Ser Gln Ile Asn Pro
                  50                  55                  60

 Asp Leu Val Arg Glu Phe Pro Asp Val Leu Glu Cys Thr Val Ser
                  65                  70                  75

 His Ala Val Glu Lys Ile Asn Pro Asp Glu Arg Glu Glu Met Lys
                  80                  85                  90

 Val Ser Ala Lys Leu Phe Ile Val Glu Ser Asn Ser Ser Ser Ser
                  95                 100                 105

 Thr Arg Ser Ala Val Asp Met Ala Cys Ser Val Leu Gly Val Ala
                 110                 115                 120

 Gln Leu Asp Ser Val Ile Ile Ala Ser Pro Pro Ile Glu Asp Gly
                 125                 130                 135

 Val Asn Leu Ser Leu Glu His Leu Gln Pro Tyr Trp Glu Glu Leu
                 140                 145                 150

 Glu Asn Leu Val Gln Ser Lys Lys Ile Val Ala Ile Gly Thr Ser
                 155                 160                 165

 Asp Leu Asp Lys Thr Gln Leu Glu Gln Leu Tyr Gln Trp Ala Gln
                 170                 175                 180

 Val Lys Pro Asn Ser Asn Gln Val Asn Leu Ala Ser Cys Cys Val
                 185                 190                 195

 Met Pro Pro Asp Leu Thr Ala Phe Ala Lys Gln Phe Asp Ile Gln
                 200                 205                 210

 Leu Leu Thr His Asn Asp Pro Lys Glu Leu Leu Ser Glu Ala Ser
                 215                 220                 225

 Phe Gln Glu Ala Leu Gln Glu Ser Ile Pro Asp Ile Gln Ala His
                 230                 235                 240

 Glu Trp Val Pro Leu Trp Leu Leu Arg Tyr Ser Val Ile Val Lys
                 245                 250                 255

 Ser Arg Gly Ile Ile Lys Ser Lys Gly Tyr Ile Leu Gln Ala Lys
                 260                 265                 270

 Arg Arg Gly Ser


<210> 1015
<211> 1052
<212> DNA
<213> Homo sapien

<400> 1015
 gctcgaatgc ccggcagccg tggcggctag agcgttcctc cccagctcga 50

 atgcccggcg gccgaggcgg ctagagcgtc gcctcctccc ggggaaccgc 100

 gtgtgacctt ccagcccgcg gaccgatgct gccggcggcc gctcgccccc 150

 tgtgggggcc ttgccttggg cttcgggccg ctgcgttccg ccttgccagg 200

 cgacaggtgc catgtgtctg tgccgtgcga catatgagga gcagcggcca 250

 tcagaggtgt gaggccctcg ctggtgcacc cctggataac gcccccaagg 300

 agtacccccc caagatacag cagctggtcc aggacatcgc cagcctcact 350

 ctcttggaaa tctcagacct caacgagctc ctgaagaaaa cgttgaagat 400

 ccaggatgtc gggcttgtgc cgatgggtgg tgtgatgtct ggggctgtcc 450

 ctgctgcagc agcccaggag gcggtggaag aagatatccc catagcgaaa 500

 gaacggacac atttcaccgt ccgcctgacc gaggcgaagc ccgtggacaa 550

 agtgaagctg atcaaggaaa tcaagaacta catccaaggc atcaacctcg 600

 tccaggcaaa gaagctggtg gagtccctgc cccaggaaat caaagccaat 650

 gtcgccaaag ctgaggcgga gaagatcaag gcggccctgg aggcggtggg 700

 cggcaccgtg gttctggagt agcctccagc tcggaggact tgtgttcagg 750

 ggtcctgggc cccgggcgag gtcccgccct cccgtggtca ctggctccgc 800

 ccccagcacc aggcgcccag tggagccgtt tgggagaatt gcctgcgcca 850

 cgcagcgggg ccggacaggc cgcacagacc tactgtggcg ggagggaggg 900

 gcggctgctg cctggtgacg gcacccggag gcccaccagg acgcgccacc 950

 ggtgaatgtg cctctggtgg ctgctgagaa aaatacactg tgcagctcag 1000

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1050

 aa 1052

<210> 1016
<211> 198
<212> PRT
<213> Homo sapien

<400> 1016
 Met Leu Pro Ala Ala Ala Arg Pro Leu Trp Gly Pro Cys Leu Gly
   1               5                  10                  15

 Leu Arg Ala Ala Ala Phe Arg Leu Ala Arg Arg Gln Val Pro Cys
                  20                  25                  30

 Val Cys Ala Val Arg His Met Arg Ser Ser Gly His Gln Arg Cys
                  35                  40                  45

 Glu Ala Leu Ala Gly Ala Pro Leu Asp Asn Ala Pro Lys Glu Tyr
                  50                  55                  60

 Pro Pro Lys Ile Gln Gln Leu Val Gln Asp Ile Ala Ser Leu Thr
                  65                  70                  75

 Leu Leu Glu Ile Ser Asp Leu Asn Glu Leu Leu Lys Lys Thr Leu
                  80                  85                  90

 Lys Ile Gln Asp Val Gly Leu Val Pro Met Gly Gly Val Met Ser
                  95                 100                 105

 Gly Ala Val Pro Ala Ala Ala Ala Gln Glu Ala Val Glu Glu Asp
                 110                 115                 120

 Ile Pro Ile Ala Lys Glu Arg Thr His Phe Thr Val Arg Leu Thr
                 125                 130                 135

 Glu Ala Lys Pro Val Asp Lys Val Lys Leu Ile Lys Glu Ile Lys
                 140                 145                 150

 Asn Tyr Ile Gln Gly Ile Asn Leu Val Gln Ala Lys Lys Leu Val
                 155                 160                 165

 Glu Ser Leu Pro Gln Glu Ile Lys Ala Asn Val Ala Lys Ala Glu
                 170                 175                 180

 Ala Glu Lys Ile Lys Ala Ala Leu Glu Ala Val Gly Gly Thr Val
                 185                 190                 195

 Val Leu Glu


<210> 1017
<211> 3547
<212> DNA
<213> Homo sapien

<400> 1017
 gcactcgccc ggctcgcccg ctttcgcacc cagttcacgc gccacagcta 50

 tgtgtccccg agccgcgcgg gcgcccgcga cgctactcct cgccctgggc 100

 gcggtgctgt ggcctgcggc tggcgcctgg gagcttacga ttttgcacac 150

 caacgacgtg cacagccggc tggagcagac cagcgaggac tccagcaagt 200

 gcgtcaacgc cagccgctgc atgggtggcg tggctcggct cttcaccaag 250

 gttcagcaga tccgccgcgc cgaacccaac gtgctgctgc tggacgccgg 300

 cgaccagtac cagggcacta tctggttcac cgtgtacaag ggcgccgagg 350

 tggcgcactt catgaacgcc ctgcgctacg atgccatggc actgggaaat 400

 catgaatttg ataatggtgt ggaaggactg atcgagccac tcctcaaaga 450

 ggccaaattt ccaattctga gtgcaaacat taaagcaaag gggccactag 500

 catctcaaat atcaggactt tatttgccat ataaagttct tcctgttggt 550

 gatgaagttg tgggaatcgt tggatacact tccaaagaaa ccccttttct 600

 ctcaaatcca gggacaaatt tagtgtttga agatgaaatc actgcattac 650

 aacctgaagt agataagtta aaaactctaa atgtgaacaa aattattgca 700

 ctgggacatt cgggttttga aatggataaa ctcatcgctc agaaagtgag 750

 gggtgtggac gtcgtggtgg gaggacactc caacacattt ctttacacag 800

 gcaatccacc ttccaaagag gtgcctgctg ggaagtaccc attcatagtc 850

 acttctgatg atgggcggaa ggttcctgta gtccaggcct atgcttttgg 900

 caaataccta ggctatctga agatcgagtt tgatgaaaga ggaaacgtca 950

 tctcttccca tggaaatccc attcttctaa acagcagcat tcctgaagat 1000

 ccaagcataa aagcagacat taacaaatgg aggataaaat tggataatta 1050

 ttctacccag gaattaggga aaacaattgt ctatctggat ggctcctctc 1100

 aatcatgccg ctttagagaa tgcaacatgg gcaacctgat ttgtgatgca 1150

 atgattaaca acaacctgag acacacggat gaaatgttct ggaaccacgt 1200

 atccatgtgc attttaaatg gaggtggtat ccggtcgccc attgatgaac 1250

 gcaacaatgg cacaattacc tgggagaacc tggctgctgt attgcccttt 1300

 ggaggcacat ttgacctagt ccagttaaaa ggttccaccc tgaagaaggc 1350

 ctttgagcat agcgtgcacc gctacggcca gtccactgga gagttcctgc 1400

 aggtgggcgg aatccatgtg gtgtatgatc tttcccgaaa acctggagac 1450

 agagtagtca aattagatgt tctttgcacc aagtgtcgag tgcccagtta 1500

 tgaccctctc aaaatggacg aggtatataa ggtgatcctc ccaaacttcc 1550

 tggccaatgg tggagatggg ttccagatga taaaagatga attattaaga 1600

 catgactctg gtgaccaaga tatcaacgtg gtttctacat atatctccaa 1650

 aatgaaagta atttatccag cagttgaagg tcggatcaag ttttccacag 1700

 gaagtcactg ccatggaagc ttttctttaa tatttctttc actttgggca 1750

 gtgatctttg ttttatacca atagccaaaa attctccttg cctttaatgt 1800

 gtgaaactgc attttttcaa gtgagattca aatctgcctt ttaggacctg 1850

 gctttgtgac agcaaaaacc atctttacag gctcctagaa gctgaaggtt 1900

 agagcattat aaaatgaaga gacagacatg attactcagg gtcagcaacc 1950

 tagtgagtta gaaaaaaaat taacataggg ccctataagg agaaagccaa 2000

 ctatgttaag tttacgtgtc caaattttaa tgaaatttta ctaacaattt 2050

 taaaccatat ttttcttctt catatccatt tctaatccat caaacagctt 2100

 atgtttacat aaaattttat cattcacaag gaagttttaa gcacactgtc 2150

 tcatttgata tccacaactt atttttggta ggaaagagag atgtttttcc 2200

 cacctgtcag atgaaaaaac tgaagctcaa aaagggttga cttgaccata 2250

 cagctaatgc tgacagatcc aagacctaga cctaggtctt ttgaactcaa 2300

 gtccagcatt ctcaactata tcaagttact gttcagaata cttaatatct 2350

 cctctcttca taattatcaa tagccccaag ctcatggatg acaaatctct 2400

 gctttatttc ttgtctctat tttttcactt tatagctcct gttataatag 2450

 caagtttaat ggtataaaca caggatacca tcctctcttg caacacccat 2500

 gtgcctttga tgagtcaggt agcaagctgt agtagataat gagaaaggcc 2550

 agaggctgca aagacagtca aaggacacga gagaaaggaa ggggaagaac 2600

 aggactccag gactgtttta tattatagaa aagcaagagc taaagagcat 2650

 ttacacatgt taaacagata cttgttaagc atagtgcctg acacacggca 2700

 ttagctgtta ttttatgaga ttccatcagc tctgcctctg tcctctttct 2750

 tctaacatga aggtatcatg agaagagaac cttctaacat aagctgtaat 2800

 tctaaacctg cacttgtccc tctccagcaa gaggctagca ctgaattcat 2850

 tctactcata ctacacaccc agttatggaa tgtccagagt tctcgaagaa 2900

 aataaatgac tttaggaaga ggtatacatt ttttaagtcg ctctgcctcc 2950

 aaatctgaac agtcactgta aatcattctt aagcccagat atgagaactt 3000

 ctgctggaaa gtgggaccct ctgagtgggt ggtcagaaaa tacccatgct 3050

 gatgaaatga cctatgccca aagaacaaat acttaacgtg ggagtggaac 3100

 cacatgagcc tgctcagctc tgcataagta attcaagaaa tgggaggctt 3150

 caccttaaaa acagtgtgca aatggcagct agaggttttg ataggaagta 3200

 tgtttgtttc ttagtgttta caaatattaa gtactcttga tacaaaatat 3250

 acttttaaac ttcataacct ttttataaaa gttgttgcag caaaataata 3300

 gcctcggttc tatgcatata tggattgcta taaaaaatgt caataagatt 3350

 gtacaaggaa aattagagaa agtcacattt agggtttatt ttttacactt 3400

 ggccagtaaa atagggtaaa tcctattaga aattttttaa agaacttttt 3450

 ttaagtttcc taaatctgtg tgtgtattgt gaagtggtat aagaaatgac 3500

 tttgaaccac tttgcaattg tagattccca acaataaaat tgaagat 3547

<210> 1018
<211> 574
<212> PRT
<213> Homo sapien

<400> 1018
 Met Cys Pro Arg Ala Ala Arg Ala Pro Ala Thr Leu Leu Leu Ala
   1               5                  10                  15

 Leu Gly Ala Val Leu Trp Pro Ala Ala Gly Ala Trp Glu Leu Thr
                  20                  25                  30

 Ile Leu His Thr Asn Asp Val His Ser Arg Leu Glu Gln Thr Ser
                  35                  40                  45

 Glu Asp Ser Ser Lys Cys Val Asn Ala Ser Arg Cys Met Gly Gly
                  50                  55                  60

 Val Ala Arg Leu Phe Thr Lys Val Gln Gln Ile Arg Arg Ala Glu
                  65                  70                  75

 Pro Asn Val Leu Leu Leu Asp Ala Gly Asp Gln Tyr Gln Gly Thr
                  80                  85                  90

 Ile Trp Phe Thr Val Tyr Lys Gly Ala Glu Val Ala His Phe Met
                  95                 100                 105

 Asn Ala Leu Arg Tyr Asp Ala Met Ala Leu Gly Asn His Glu Phe
                 110                 115                 120

 Asp Asn Gly Val Glu Gly Leu Ile Glu Pro Leu Leu Lys Glu Ala
                 125                 130                 135

 Lys Phe Pro Ile Leu Ser Ala Asn Ile Lys Ala Lys Gly Pro Leu
                 140                 145                 150

 Ala Ser Gln Ile Ser Gly Leu Tyr Leu Pro Tyr Lys Val Leu Pro
                 155                 160                 165

 Val Gly Asp Glu Val Val Gly Ile Val Gly Tyr Thr Ser Lys Glu
                 170                 175                 180

 Thr Pro Phe Leu Ser Asn Pro Gly Thr Asn Leu Val Phe Glu Asp
                 185                 190                 195

 Glu Ile Thr Ala Leu Gln Pro Glu Val Asp Lys Leu Lys Thr Leu
                 200                 205                 210

 Asn Val Asn Lys Ile Ile Ala Leu Gly His Ser Gly Phe Glu Met
                 215                 220                 225

 Asp Lys Leu Ile Ala Gln Lys Val Arg Gly Val Asp Val Val Val
                 230                 235                 240

 Gly Gly His Ser Asn Thr Phe Leu Tyr Thr Gly Asn Pro Pro Ser
                 245                 250                 255

 Lys Glu Val Pro Ala Gly Lys Tyr Pro Phe Ile Val Thr Ser Asp
                 260                 265                 270

 Asp Gly Arg Lys Val Pro Val Val Gln Ala Tyr Ala Phe Gly Lys
                 275                 280                 285

 Tyr Leu Gly Tyr Leu Lys Ile Glu Phe Asp Glu Arg Gly Asn Val
                 290                 295                 300

 Ile Ser Ser His Gly Asn Pro Ile Leu Leu Asn Ser Ser Ile Pro
                 305                 310                 315

 Glu Asp Pro Ser Ile Lys Ala Asp Ile Asn Lys Trp Arg Ile Lys
                 320                 325                 330

 Leu Asp Asn Tyr Ser Thr Gln Glu Leu Gly Lys Thr Ile Val Tyr
                 335                 340                 345

 Leu Asp Gly Ser Ser Gln Ser Cys Arg Phe Arg Glu Cys Asn Met
                 350                 355                 360

 Gly Asn Leu Ile Cys Asp Ala Met Ile Asn Asn Asn Leu Arg His
                 365                 370                 375

 Thr Asp Glu Met Phe Trp Asn His Val Ser Met Cys Ile Leu Asn
                 380                 385                 390

 Gly Gly Gly Ile Arg Ser Pro Ile Asp Glu Arg Asn Asn Gly Thr
                 395                 400                 405

 Ile Thr Trp Glu Asn Leu Ala Ala Val Leu Pro Phe Gly Gly Thr
                 410                 415                 420

 Phe Asp Leu Val Gln Leu Lys Gly Ser Thr Leu Lys Lys Ala Phe
                 425                 430                 435

 Glu His Ser Val His Arg Tyr Gly Gln Ser Thr Gly Glu Phe Leu
                 440                 445                 450

 Gln Val Gly Gly Ile His Val Val Tyr Asp Leu Ser Arg Lys Pro
                 455                 460                 465

 Gly Asp Arg Val Val Lys Leu Asp Val Leu Cys Thr Lys Cys Arg
                 470                 475                 480

 Val Pro Ser Tyr Asp Pro Leu Lys Met Asp Glu Val Tyr Lys Val
                 485                 490                 495

 Ile Leu Pro Asn Phe Leu Ala Asn Gly Gly Asp Gly Phe Gln Met
                 500                 505                 510

 Ile Lys Asp Glu Leu Leu Arg His Asp Ser Gly Asp Gln Asp Ile
                 515                 520                 525

 Asn Val Val Ser Thr Tyr Ile Ser Lys Met Lys Val Ile Tyr Pro
                 530                 535                 540

 Ala Val Glu Gly Arg Ile Lys Phe Ser Thr Gly Ser His Cys His
                 545                 550                 555

 Gly Ser Phe Ser Leu Ile Phe Leu Ser Leu Trp Ala Val Ile Phe
                 560                 565                 570

 Val Leu Tyr Gln


<210> 1019
<211> 1886
<212> DNA
<213> Homo sapien

<400> 1019
 gcggagctct gccttggaga ttctcagtgc tgcggatcat gtccctaagg 50

 ggcagcctct cgcgtctcct ccagacgcga gtgcattcca tcctgaagaa 100

 atccgtccac tccgtggctg tgataggagc cccgttctca caagggcaga 150

 aaagaaaagg agtggagcat ggtcccgctg ccataagaga agctggcttg 200

 atgaaaaggc tctccagttt gggctgccac ctaaaagact ttggagattt 250

 gagttttact ccagtcccca aagatgatct ctacaacaac ctgatagtga 300

 atccacgctc agtgggtctt gccaaccagg aactggctga ggtggttagc 350

 agagctgtgt cagatggcta cagctgtgtc acactgggag gagaccacag 400

 cctggcaatc ggtaccatta gtggccatgc ccgacactgc ccagaccttt 450

 gtgttgtctg ggttgatgcc catgctgaca tcaacacacc ccttaccact 500

 tcatcaggaa atctccatgg acagccagtt tcatttctcc tcagagaact 550

 acaggataag gtaccacaac tcccaggatt ttcctggatc aaaccttgta 600

 tctcttctgc aagtattgtg tatattggtc tgagagacgt ggaccctcct 650

 gaacatttta ttttaaagaa ctatgatatc cagtattttt ccatgagaga 700

 tattgatcga cttggtatcc agaaggtcat ggaacgaaca tttgatctgc 750

 tgattggcaa gagacaaaga ccaatccatt tgagttttga tattgatgca 800

 tttgacccta cactggctcc agccacagga actcctgttg tcgggggact 850

 aacctatcga gaaggcatgt atattgctga ggaaatacac aatacagggt 900

 tgctatcagc actggatctt gttgaagtca atcctcagtt ggccacctca 950

 gaggaagagg cgaagactac agctaacctg gcagtagatg tgattgcttc 1000

 aagctttggt cagacaagag aaggagggca tattgtctat gaccaacttc 1050

 ctactcccag ttcaccagat gaatcagaaa atcaagcacg tgtgagaatt 1100

 taggagacac tgtgcactga catgtttcac aacaggcatt ccagaattat 1150

 gaggcattga ggggatagat gaatactaaa tggttgtctg ggtcaatact 1200

 gccttaatga gaacatttac acattctcac aattgtaaag tttcccctct 1250

 attttggtga ccaatactac tgtaaatgta tttggttttt tgcagttcac 1300

 agggtattaa tatgctacag tactatgtaa atttaaagaa gtcataaaca 1350

 gcatttatta ccttggtata tcatactggt cttgttgctg ttgttccttc 1400

 acatttaagt ggtttttcat ctttcctccc tcctcccaca gcctggctat 1450

 acagtgcatc cttgaactgt cagcccacag cagcaatatg cttattctat 1500

 ccacatccct aacatcatgc attcacaagg tcaaagttct ggtccacaaa 1550

 cccttcccta tagaagttca atggctgcga aagaatttgt agtaaaccag 1600

 gcctcccagg atggcgagct ccagtaagat gataatggaa agcagcagct 1650

 tgttggttgt cactctacaa agagaagcaa agtggggagt agtcagaagt 1700

 ttggataacc ttccttctaa acatttgggg gttagacctg ggaccacggc 1750

 tggatactct gaggctgtat gtttgatcac acagccactt agcaggaagt 1800

 actcataagg ttctttagct gtcacttagg gataacactg tctacctcac 1850

 agaaatgtta aactgagaca ataaaaccca aagcat 1886

<210> 1020
<211> 354
<212> PRT
<213> Homo sapien

<400> 1020
 Met Ser Leu Arg Gly Ser Leu Ser Arg Leu Leu Gln Thr Arg Val
   1               5                  10                  15

 His Ser Ile Leu Lys Lys Ser Val His Ser Val Ala Val Ile Gly
                  20                  25                  30

 Ala Pro Phe Ser Gln Gly Gln Lys Arg Lys Gly Val Glu His Gly
                  35                  40                  45

 Pro Ala Ala Ile Arg Glu Ala Gly Leu Met Lys Arg Leu Ser Ser
                  50                  55                  60

 Leu Gly Cys His Leu Lys Asp Phe Gly Asp Leu Ser Phe Thr Pro
                  65                  70                  75

 Val Pro Lys Asp Asp Leu Tyr Asn Asn Leu Ile Val Asn Pro Arg
                  80                  85                  90

 Ser Val Gly Leu Ala Asn Gln Glu Leu Ala Glu Val Val Ser Arg
                  95                 100                 105

 Ala Val Ser Asp Gly Tyr Ser Cys Val Thr Leu Gly Gly Asp His
                 110                 115                 120

 Ser Leu Ala Ile Gly Thr Ile Ser Gly His Ala Arg His Cys Pro
                 125                 130                 135

 Asp Leu Cys Val Val Trp Val Asp Ala His Ala Asp Ile Asn Thr
                 140                 145                 150

 Pro Leu Thr Thr Ser Ser Gly Asn Leu His Gly Gln Pro Val Ser
                 155                 160                 165

 Phe Leu Leu Arg Glu Leu Gln Asp Lys Val Pro Gln Leu Pro Gly
                 170                 175                 180

 Phe Ser Trp Ile Lys Pro Cys Ile Ser Ser Ala Ser Ile Val Tyr
                 185                 190                 195

 Ile Gly Leu Arg Asp Val Asp Pro Pro Glu His Phe Ile Leu Lys
                 200                 205                 210

 Asn Tyr Asp Ile Gln Tyr Phe Ser Met Arg Asp Ile Asp Arg Leu
                 215                 220                 225

 Gly Ile Gln Lys Val Met Glu Arg Thr Phe Asp Leu Leu Ile Gly
                 230                 235                 240

 Lys Arg Gln Arg Pro Ile His Leu Ser Phe Asp Ile Asp Ala Phe
                 245                 250                 255

 Asp Pro Thr Leu Ala Pro Ala Thr Gly Thr Pro Val Val Gly Gly
                 260                 265                 270

 Leu Thr Tyr Arg Glu Gly Met Tyr Ile Ala Glu Glu Ile His Asn
                 275                 280                 285

 Thr Gly Leu Leu Ser Ala Leu Asp Leu Val Glu Val Asn Pro Gln
                 290                 295                 300

 Leu Ala Thr Ser Glu Glu Glu Ala Lys Thr Thr Ala Asn Leu Ala
                 305                 310                 315

 Val Asp Val Ile Ala Ser Ser Phe Gly Gln Thr Arg Glu Gly Gly
                 320                 325                 330

 His Ile Val Tyr Asp Gln Leu Pro Thr Pro Ser Ser Pro Asp Glu
                 335                 340                 345

 Ser Glu Asn Gln Ala Arg Val Arg Ile
                 350

<210> 1021
<211> 1886
<212> DNA
<213> Homo sapien

<400> 1021
 gcggagctct gccttggaga ttctcagtgc tgcggatcat gtccctaagg 50

 ggcagcctct cgcgtctcct ccagacgcga gtgcattcca tcctgaagaa 100

 atccgtccac tccgtggctg tgataggagc cccgttctca caagggcaga 150

 aaagaaaagg agtggagcat ggtcccgctg ccataagaga agctggcttg 200

 atgaaaaggc tctccagttt gggctgccac ctaaaagact ttggagattt 250

 gagttttact ccagtcccca aagatgatct ctacaacaac ctgatagtga 300

 atccacgctc agtgggtctt gccaaccagg aactggctga ggtggttagc 350

 agagctgtgt cagatggcta cagctgtgtc acactgggag gagaccacag 400

 cctggcaatc ggtaccatta gtggccatgc ccgacactgc ccagaccttt 450

 gtgttgtctg ggttgatgcc catgctgaca tcaacacacc ccttaccact 500

 tcatcaggaa atctccatgg acagccagtt tcatttctcc tcagagaact 550

 acaggataag gtaccacaac tcccaggatt ttcctggatc aaaccttgta 600

 tctcttctgc aagtattgtg tatattggtc tgagagacgt ggaccctcct 650

 gaacatttta ttttaaagaa ctatgatatc cagtattttt ccatgagaga 700

 tattgatcga cttggtatcc agaaggtcat ggaacgaaca tttgatctgc 750

 tgattggcaa gagacaaaga ccaatccatt tgagttttga tattgatgca 800

 tttgacccta cactggctcc agccacagga actcctgttg tcgggggact 850

 aacctatcga gaaggcatgt atattgctga ggaaatacac aatacagggt 900

 tgctatcagc actggatctt gttgaagtca atcctcagtt ggccacctca 950

 gaggaagagg cgaagactac agctaacctg gcagtagatg tgattgcttc 1000

 aagctttggt cagacaagag aaggagggca tattgtctat gaccaacttc 1050

 ctactcccag ttcaccagat gaatcagaaa atcaagcacg tgtgagaatt 1100

 taggagacac tgtgcactga catgtttcac aacaggcatt ccagaattat 1150

 gaggcattga ggggatagat gaatactaaa tggttgtctg ggtcaatact 1200

 gccttaatga gaacatttac acattctcac aattgtaaag tttcccctct 1250

 attttggtga ccaatactac tgtaaatgta tttggttttt tgcagttcac 1300

 agggtattaa tatgctacag tactatgtaa atttaaagaa gtcataaaca 1350

 gcatttatta ccttggtata tcatactggt cttgttgctg ttgttccttc 1400

 acatttaagt ggtttttcat ctttcctccc tcctcccaca gcctggctat 1450

 acagtgcatc cttgaactgt cagcccacag cagcaatatg cttattctat 1500

 ccacatccct aacatcatgc attcacaagg tcaaagttct ggtccacaaa 1550

 cccttcccta tagaagttca atggctgcga aagaatttgt agtaaaccag 1600

 gcctcccagg atggcgagct ccagtaagat gataatggaa agcagcagct 1650

 tgttggttgt cactctacaa agagaagcaa agtggggagt agtcagaagt 1700

 ttggataacc ttccttctaa acatttgggg gttagacctg ggaccacggc 1750

 tggatactct gaggctgtat gtttgatcac acagccactt agcaggaagt 1800

 actcataagg ttctttagct gtcacttagg gataacactg tctacctcac 1850

 agaaatgtta aactgagaca ataaaaccca aagcat 1886

<210> 1022
<211> 354
<212> PRT
<213> Homo sapien

<400> 1022
 Met Ser Leu Arg Gly Ser Leu Ser Arg Leu Leu Gln Thr Arg Val
   1               5                  10                  15

 His Ser Ile Leu Lys Lys Ser Val His Ser Val Ala Val Ile Gly
                  20                  25                  30

 Ala Pro Phe Ser Gln Gly Gln Lys Arg Lys Gly Val Glu His Gly
                  35                  40                  45

 Pro Ala Ala Ile Arg Glu Ala Gly Leu Met Lys Arg Leu Ser Ser
                  50                  55                  60

 Leu Gly Cys His Leu Lys Asp Phe Gly Asp Leu Ser Phe Thr Pro
                  65                  70                  75

 Val Pro Lys Asp Asp Leu Tyr Asn Asn Leu Ile Val Asn Pro Arg
                  80                  85                  90

 Ser Val Gly Leu Ala Asn Gln Glu Leu Ala Glu Val Val Ser Arg
                  95                 100                 105

 Ala Val Ser Asp Gly Tyr Ser Cys Val Thr Leu Gly Gly Asp His
                 110                 115                 120

 Ser Leu Ala Ile Gly Thr Ile Ser Gly His Ala Arg His Cys Pro
                 125                 130                 135

 Asp Leu Cys Val Val Trp Val Asp Ala His Ala Asp Ile Asn Thr
                 140                 145                 150

 Pro Leu Thr Thr Ser Ser Gly Asn Leu His Gly Gln Pro Val Ser
                 155                 160                 165

 Phe Leu Leu Arg Glu Leu Gln Asp Lys Val Pro Gln Leu Pro Gly
                 170                 175                 180

 Phe Ser Trp Ile Lys Pro Cys Ile Ser Ser Ala Ser Ile Val Tyr
                 185                 190                 195

 Ile Gly Leu Arg Asp Val Asp Pro Pro Glu His Phe Ile Leu Lys
                 200                 205                 210

 Asn Tyr Asp Ile Gln Tyr Phe Ser Met Arg Asp Ile Asp Arg Leu
                 215                 220                 225

 Gly Ile Gln Lys Val Met Glu Arg Thr Phe Asp Leu Leu Ile Gly
                 230                 235                 240

 Lys Arg Gln Arg Pro Ile His Leu Ser Phe Asp Ile Asp Ala Phe
                 245                 250                 255

 Asp Pro Thr Leu Ala Pro Ala Thr Gly Thr Pro Val Val Gly Gly
                 260                 265                 270

 Leu Thr Tyr Arg Glu Gly Met Tyr Ile Ala Glu Glu Ile His Asn
                 275                 280                 285

 Thr Gly Leu Leu Ser Ala Leu Asp Leu Val Glu Val Asn Pro Gln
                 290                 295                 300

 Leu Ala Thr Ser Glu Glu Glu Ala Lys Thr Thr Ala Asn Leu Ala
                 305                 310                 315

 Val Asp Val Ile Ala Ser Ser Phe Gly Gln Thr Arg Glu Gly Gly
                 320                 325                 330

 His Ile Val Tyr Asp Gln Leu Pro Thr Pro Ser Ser Pro Asp Glu
                 335                 340                 345

 Ser Glu Asn Gln Ala Arg Val Arg Ile
                 350

<210> 1023
<211> 1295
<212> DNA
<213> Homo sapien

<400> 1023
 cacgtcagcc ggggctagaa aaggcggcgg ggctgggccc agcgaggtga 50

 cagcctcgct tggacgcaga gcccggcccg acgccgccat gagcgccgcg 100

 ctcttcagcc tggacggccc ggcgcgcggc gcgccctggc ctgcggagcc 150

 tgcgcccttc tacgaaccgg gccgggcggg caagccgggc cgcggggccg 200

 agccaggggc cctaggcgag ccaggcgccg ccgcccccgc catgtacgac 250

 gacgagagcg ccatcgactt cagcgcctac atcgactcca tggccgccgt 300

 gcccaccctg gagctgtgcc acgacgagct cttcgccgac ctcttcaaca 350

 gcaatcacaa ggcgggcggc gcggggcccc tggagcttct tcccggcggc 400

 cccgcgcgcc ccttgggccc gggccctgcc gctccccgcc tgctcaagcg 450

 cgagcccgac tggggcgacg gcgacgcgcc cggctcgctg ttgcccgcgc 500

 aggtggccgc gtgcgcacag accgtggtga gcttggcggc cgcagggcag 550

 cccaccccgc ccacgtcgcc ggagccgccg cgcagcagcc ccaggcagac 600

 ccccgcgccc ggccccgccc gggagaagag cgccggcaag aggggcccgg 650

 accgcggcag ccccgagtac cggcagcggc gcgagcgcaa caacatcgcc 700

 gtgcgcaaga gccgcgacaa ggccaagcgg cgcaaccagg agatgcagca 750

 gaagttggtg gagctgtcgg ctgagaacga gaagctgcac cagcgcgtgg 800

 agcagctcac gcgggacctg gccggcctcc ggcagttctt caagcagctg 850

 cccagcccgc ccttcctgcc ggccgccggg acagcagact gccggtaacg 900

 cgcggccggg gcgggagaga ctcagcaacg acccatacct cagacccgac 950

 ggcccggagc ggagcgcgcc ctgccctggc gcagccagag ccgccgggtg 1000

 cccgctgcag tttcttggga cataggagcg caaagaagct acagcctgga 1050

 cttaccacca ctaaactgcg agagaagcta aacgtgttta ttttccctta 1100

 aattattttt gtaatggtag ctttttctac atcttactcc tgttgatgca 1150

 gctaaggtac atttgtaaaa agaaaaaaaa ccagactttt cagacaaacc 1200

 ctttgtattg tagataagag gaaaagactg agcatgctca cttttttata 1250

 ttaattttta cagtatttgt aagaataaag cagcatttga aatcg 1295

<210> 1024
<211> 269
<212> PRT
<213> Homo sapien

<400> 1024
 Met Ser Ala Ala Leu Phe Ser Leu Asp Gly Pro Ala Arg Gly Ala
   1               5                  10                  15

 Pro Trp Pro Ala Glu Pro Ala Pro Phe Tyr Glu Pro Gly Arg Ala
                  20                  25                  30

 Gly Lys Pro Gly Arg Gly Ala Glu Pro Gly Ala Leu Gly Glu Pro
                  35                  40                  45

 Gly Ala Ala Ala Pro Ala Met Tyr Asp Asp Glu Ser Ala Ile Asp
                  50                  55                  60

 Phe Ser Ala Tyr Ile Asp Ser Met Ala Ala Val Pro Thr Leu Glu
                  65                  70                  75

 Leu Cys His Asp Glu Leu Phe Ala Asp Leu Phe Asn Ser Asn His
                  80                  85                  90

 Lys Ala Gly Gly Ala Gly Pro Leu Glu Leu Leu Pro Gly Gly Pro
                  95                 100                 105

 Ala Arg Pro Leu Gly Pro Gly Pro Ala Ala Pro Arg Leu Leu Lys
                 110                 115                 120

 Arg Glu Pro Asp Trp Gly Asp Gly Asp Ala Pro Gly Ser Leu Leu
                 125                 130                 135

 Pro Ala Gln Val Ala Ala Cys Ala Gln Thr Val Val Ser Leu Ala
                 140                 145                 150

 Ala Ala Gly Gln Pro Thr Pro Pro Thr Ser Pro Glu Pro Pro Arg
                 155                 160                 165

 Ser Ser Pro Arg Gln Thr Pro Ala Pro Gly Pro Ala Arg Glu Lys
                 170                 175                 180

 Ser Ala Gly Lys Arg Gly Pro Asp Arg Gly Ser Pro Glu Tyr Arg
                 185                 190                 195

 Gln Arg Arg Glu Arg Asn Asn Ile Ala Val Arg Lys Ser Arg Asp
                 200                 205                 210

 Lys Ala Lys Arg Arg Asn Gln Glu Met Gln Gln Lys Leu Val Glu
                 215                 220                 225

 Leu Ser Ala Glu Asn Glu Lys Leu His Gln Arg Val Glu Gln Leu
                 230                 235                 240

 Thr Arg Asp Leu Ala Gly Leu Arg Gln Phe Phe Lys Gln Leu Pro
                 245                 250                 255

 Ser Pro Pro Phe Leu Pro Ala Ala Gly Thr Ala Asp Cys Arg
                 260                 265

<210> 1025
<211> 3342
<212> DNA
<213> Homo sapien

<400> 1025
 gcagctccag tcccggacgc aaccccggag ccgtctcagg tccctggggg 50

 gaacggtggg ttagacgggg acgggaaggg acagcggcct tcgaccgccc 100

 cccgagtaat tgacccagga ctcattttca ggaaagcctg aaaatgagta 150

 aaatagtgaa atgaggaatt tgaacatttt atctttggat ggggatcttc 200

 tgaggatgca aagagtgatt catccaagcc atgtggtaaa atcaggaatt 250

 tgaagaaaat ggagatgttt acatttttgt tgacgtgtat ttttctaccc 300

 ctcctaagag ggcacagtct cttcacctgt gaaccaatta ctgttcccag 350

 atgtatgaaa atggcctaca acatgacgtt tttccctaat ctgatgggtc 400

 attatgacca gagtattgcc gcggtggaaa tggagcattt tcttcctctc 450

 gcaaatctgg aatgttcacc aaacattgaa actttcctct gcaaagcatt 500

 tgtaccaacc tgcatagaac aaattcatgt ggttccacct tgtcgtaaac 550

 tttgtgagaa agtatattct gattgcaaaa aattaattga cacttttggg 600

 atccgatggc ctgaggagct tgaatgtgac agattacaat actgtgatga 650

 gactgttcct gtaacttttg atccacacac agaatttctt ggtcctcaga 700

 agaaaacaga acaagtccaa agagacattg gattttggtg tccaaggcat 750

 cttaagactt ctgggggaca aggatataag tttctgggaa ttgaccagtg 800

 tgcgcctcca tgccccaaca tgtattttaa aagtgatgag ctagagtttg 850

 caaaaagttt tattggaaca gtttcaatat tttgtctttg tgcaactctg 900

 ttcacattcc ttactttttt aattgatgtt agaagattca gatacccaga 950

 gagaccaatt atatattact ctgtctgtta cagcattgta tctcttatgt 1000

 acttcattgg atttttgctg ggcgatagca cagcctgcaa taaggcagat 1050

 gagaagctag aacttggtga cactgttgtc ctaggctctc aaaataaggc 1100

 ttgcaccgtt ttgttcatgc ttttgtattt tttcacaatg gctggcactg 1150

 tgtggtgggt gattcttacc attacttggt tcttagctgc aggaagaaaa 1200

 tggagttgtg aagccatcga gcaaaaagca gtgtggtttc atgctgttgc 1250

 atggggaaca ccaggtttcc tgactgttat gcttcttgct ctgaacaaag 1300

 ttgaaggaga caacattagt ggagtttgct ttgttggcct ttatgacctg 1350

 gatgcttctc gctactttgt actcttgcca ctgtgccttt gtgtgtttgt 1400

 tgggctctct cttcttttag ctggcattat ttccttaaat catgttcgac 1450

 aagtcataca acatgatggc cggaaccaag aaaaactaaa gaaatttatg 1500

 attcgaattg gagtcttcag cggcttgtat cttgtgccat tagtgacact 1550

 tctcggatgt tacgtctatg agcaagtgaa caggattacc tgggagataa 1600

 cttgggtctc tgatcattgt cgtcagtacc atatcccatg tccttatcag 1650

 gcaaaagcaa aagctcgacc agaattggct ttatttatga taaaatacct 1700

 gatgacatta attgttggca tctctgctgt cttctgggtt ggaagcaaaa 1750

 agacatgcac agaatgggct gggtttttta aacgaaatcg caagagagat 1800

 ccaatcagtg aaagtcgaag agtactacag gaatcatgtg agtttttctt 1850

 aaagcacaat tctaaagtta aacacaaaaa gaagcactat aaaccaagtt 1900

 cacacaagct gaaggtcatt tccaaatcca tgggaaccag cacaggagct 1950

 acagcaaatc atggcacttc tgcagtagca attactagcc atgattacct 2000

 aggacaagaa actttgacag aaatccaaac ctcaccagaa acatcaatga 2050

 gagaggtgaa agcggacgga gctagcaccc ccaggttaag agaacaggac 2100

 tgtggtgaac ctgcctcgcc agcagcatcc atctccagac tctctgggga 2150

 acaggtcgac gggaagggcc aggcaggcag tgtatctgaa agtgcgcgga 2200

 gtgaaggaag gattagtcca aagagtgata ttactgacac tggcctggca 2250

 cagagcaaca atttgcaggt ccccagttct tcagaaccaa gcagcctcaa 2300

 aggttccaca tctctgcttg ttcacccagt ttcaggagtg agaaaagagc 2350

 agggaggtgg ttgtcattca gatacttgaa gaacattttc tctcgttact 2400

 cagaagcaaa tttgtgttac actggaagtg acctatgcac tgttttgtaa 2450

 gaatcactgt tacgttcttc ttttgcactt aaagttgcat tgcctactgt 2500

 tatactggaa aaaatagagt tcaagaataa tatgactcat ttcacacaaa 2550

 ggttaatgac aacaatatac ctgaaaacag aaatgtgcag gttaataata 2600

 tttttttaat agtgtgggag gacagagtta gaggaatctt ccttttctat 2650

 ttatgaagat tctactcttg gtaagagtat tttaagatgt actatgctat 2700

 tttacctttt tgatataaaa tcaagatatt tctttgctga agtatttaaa 2750

 tcttatcctt gtatcttttt atacatattt gaaaataagc ttatatgtat 2800

 ttgaactttt ttgaaatcct attcaagtat ttttatcatg ctattgtgat 2850

 attttagcac tttggtagct tttacactga atttctaaga aaattgtaaa 2900

 atagtcttct tttatactgt aaaaaaagat ataccaaaaa gtcttataat 2950

 aggaatttaa ctttaaaaac ccacttattg ataccttacc atctaaaatg 3000

 tgtgattttt atagtctcgt tttaggaatt tcacagatct aaattatgta 3050

 actgaaataa ggtgcttact caaagagtgt ccactattga ttgtattatg 3100

 ctgctcactg atccttctgc atatttaaaa taaaatgtcc taaagggtta 3150

 gtagacaaaa tgttagtctt ttgtatatta ggccaagtgc aattgacttc 3200

 ccttttttaa tgtttcatga ccacccattg attgtattat aaccacttac 3250

 agttgcttat attttttgtt ttaacttttg tttcttaaca tttagaatat 3300

 tacattttgt attatacagt acctttctca gacattttgt ag 3342

<210> 1026
<211> 706
<212> PRT
<213> Homo sapien

<400> 1026
 Met Glu Met Phe Thr Phe Leu Leu Thr Cys Ile Phe Leu Pro Leu
   1               5                  10                  15

 Leu Arg Gly His Ser Leu Phe Thr Cys Glu Pro Ile Thr Val Pro
                  20                  25                  30

 Arg Cys Met Lys Met Ala Tyr Asn Met Thr Phe Phe Pro Asn Leu
                  35                  40                  45

 Met Gly His Tyr Asp Gln Ser Ile Ala Ala Val Glu Met Glu His
                  50                  55                  60

 Phe Leu Pro Leu Ala Asn Leu Glu Cys Ser Pro Asn Ile Glu Thr
                  65                  70                  75

 Phe Leu Cys Lys Ala Phe Val Pro Thr Cys Ile Glu Gln Ile His
                  80                  85                  90

 Val Val Pro Pro Cys Arg Lys Leu Cys Glu Lys Val Tyr Ser Asp
                  95                 100                 105

 Cys Lys Lys Leu Ile Asp Thr Phe Gly Ile Arg Trp Pro Glu Glu
                 110                 115                 120

 Leu Glu Cys Asp Arg Leu Gln Tyr Cys Asp Glu Thr Val Pro Val
                 125                 130                 135

 Thr Phe Asp Pro His Thr Glu Phe Leu Gly Pro Gln Lys Lys Thr
                 140                 145                 150

 Glu Gln Val Gln Arg Asp Ile Gly Phe Trp Cys Pro Arg His Leu
                 155                 160                 165

 Lys Thr Ser Gly Gly Gln Gly Tyr Lys Phe Leu Gly Ile Asp Gln
                 170                 175                 180

 Cys Ala Pro Pro Cys Pro Asn Met Tyr Phe Lys Ser Asp Glu Leu
                 185                 190                 195

 Glu Phe Ala Lys Ser Phe Ile Gly Thr Val Ser Ile Phe Cys Leu
                 200                 205                 210

 Cys Ala Thr Leu Phe Thr Phe Leu Thr Phe Leu Ile Asp Val Arg
                 215                 220                 225

 Arg Phe Arg Tyr Pro Glu Arg Pro Ile Ile Tyr Tyr Ser Val Cys
                 230                 235                 240

 Tyr Ser Ile Val Ser Leu Met Tyr Phe Ile Gly Phe Leu Leu Gly
                 245                 250                 255

 Asp Ser Thr Ala Cys Asn Lys Ala Asp Glu Lys Leu Glu Leu Gly
                 260                 265                 270

 Asp Thr Val Val Leu Gly Ser Gln Asn Lys Ala Cys Thr Val Leu
                 275                 280                 285

 Phe Met Leu Leu Tyr Phe Phe Thr Met Ala Gly Thr Val Trp Trp
                 290                 295                 300

 Val Ile Leu Thr Ile Thr Trp Phe Leu Ala Ala Gly Arg Lys Trp
                 305                 310                 315

 Ser Cys Glu Ala Ile Glu Gln Lys Ala Val Trp Phe His Ala Val
                 320                 325                 330

 Ala Trp Gly Thr Pro Gly Phe Leu Thr Val Met Leu Leu Ala Leu
                 335                 340                 345

 Asn Lys Val Glu Gly Asp Asn Ile Ser Gly Val Cys Phe Val Gly
                 350                 355                 360

 Leu Tyr Asp Leu Asp Ala Ser Arg Tyr Phe Val Leu Leu Pro Leu
                 365                 370                 375

 Cys Leu Cys Val Phe Val Gly Leu Ser Leu Leu Leu Ala Gly Ile
                 380                 385                 390

 Ile Ser Leu Asn His Val Arg Gln Val Ile Gln His Asp Gly Arg
                 395                 400                 405

 Asn Gln Glu Lys Leu Lys Lys Phe Met Ile Arg Ile Gly Val Phe
                 410                 415                 420

 Ser Gly Leu Tyr Leu Val Pro Leu Val Thr Leu Leu Gly Cys Tyr
                 425                 430                 435

 Val Tyr Glu Gln Val Asn Arg Ile Thr Trp Glu Ile Thr Trp Val
                 440                 445                 450

 Ser Asp His Cys Arg Gln Tyr His Ile Pro Cys Pro Tyr Gln Ala
                 455                 460                 465

 Lys Ala Lys Ala Arg Pro Glu Leu Ala Leu Phe Met Ile Lys Tyr
                 470                 475                 480

 Leu Met Thr Leu Ile Val Gly Ile Ser Ala Val Phe Trp Val Gly
                 485                 490                 495

 Ser Lys Lys Thr Cys Thr Glu Trp Ala Gly Phe Phe Lys Arg Asn
                 500                 505                 510

 Arg Lys Arg Asp Pro Ile Ser Glu Ser Arg Arg Val Leu Gln Glu
                 515                 520                 525

 Ser Cys Glu Phe Phe Leu Lys His Asn Ser Lys Val Lys His Lys
                 530                 535                 540

 Lys Lys His Tyr Lys Pro Ser Ser His Lys Leu Lys Val Ile Ser
                 545                 550                 555

 Lys Ser Met Gly Thr Ser Thr Gly Ala Thr Ala Asn His Gly Thr
                 560                 565                 570

 Ser Ala Val Ala Ile Thr Ser His Asp Tyr Leu Gly Gln Glu Thr
                 575                 580                 585

 Leu Thr Glu Ile Gln Thr Ser Pro Glu Thr Ser Met Arg Glu Val
                 590                 595                 600

 Lys Ala Asp Gly Ala Ser Thr Pro Arg Leu Arg Glu Gln Asp Cys
                 605                 610                 615

 Gly Glu Pro Ala Ser Pro Ala Ala Ser Ile Ser Arg Leu Ser Gly
                 620                 625                 630

 Glu Gln Val Asp Gly Lys Gly Gln Ala Gly Ser Val Ser Glu Ser
                 635                 640                 645

 Ala Arg Ser Glu Gly Arg Ile Ser Pro Lys Ser Asp Ile Thr Asp
                 650                 655                 660

 Thr Gly Leu Ala Gln Ser Asn Asn Leu Gln Val Pro Ser Ser Ser
                 665                 670                 675

 Glu Pro Ser Ser Leu Lys Gly Ser Thr Ser Leu Leu Val His Pro
                 680                 685                 690

 Val Ser Gly Val Arg Lys Glu Gln Gly Gly Gly Cys His Ser Asp
                 695                 700                 705

 Thr


<210> 1027
<211> 2682
<212> DNA
<213> Homo sapien

<400> 1027
 agcgggctgt gcctcagtca gtggcgccga aggctccgtt aagcggcggc 50

 ggcggttcct gtttccgttt cttcctctcc gttcggtcgg gagtagcatc 100

 ctccactcag ccacccttcc cactccccca tcgtggggca gctgcggctg 150

 agggctgtgg ctttggcagc tgcgacgggg agcggcggag accgcctctg 200

 ctcccgcctg gggttgctgc ttttgctcag aggacatcca tgaccctaat 250

 ggtctttttg ttcaagataa agtgattttt tgcctttgtt gattaactgg 300

 acaaattcag gataccagaa ggccctattg atcaggggcc agctatagga 350

 agagtacgcg ttttagaaga gcagcttgtt aaggccaaag aacagattga 400

 aaattacaag aaacagacca gaaatggtct ggggaaggat catgaaatcc 450

 tgaggaggag gattgaaaat ggagctaaag agctctggtt tttcctacag 500

 agtgaattga agaaattaaa gaacttagaa ggaaatgaac tccaaagaca 550

 tgcagatgaa tttcttttgg atttaggaca tcatgaaagg attctgatgg 600

 caattactgt ctcattagtg aacaataaaa gaaaaattgt tgtattagca 650

 caacctacta ctgtgaagag gaaaagaatt accccataca agtctataat 700

 gacggatcta tactacctca gtcagacaga tggagcaggt gattggcggg 750

 aaaaagaggc caaagatctg acagaactgg ttcagcggag aataacatat 800

 cttcagaatc ccaaggactg cagcaaagcc aaaaagctgg tgtgtaatat 850

 caacaaaggc tgtggctatg gctgtcagct ccatcatgtg gtctactgct 900

 tcatgattgc atatggcacc cagcgaacac tcatcttgga atctcagaat 950

 tggcgctatg ctactggtgg atgggagact gtatttaggc ctgtaagtga 1000

 gacatgcaca gacagatctg gcatctccac tggacactgg tcaggtgaag 1050

 tgaaggacaa aaatgttcaa gtggtcgagt ttcccattgt agacagtctt 1100

 catccccgtc ctccatattt acccttggct gtaccagaag acctcgcaga 1150

 tcgacttgta cgagtgcatg gtgaccctgc agtgtggtgg gtgtctcagt 1200

 ttgtcaaata cttgatccgc ccacagcctt ggctagaaaa agaaatagaa 1250

 gaagccacca agaagcttgg cttcaaacat ccagttattg gagtccatgt 1300

 cagacgcaca gacaaagtgg gaacagaagc tgccttccat cccattgaag 1350

 agtacatggt gcatgttgaa gaacattttc agcttcttgc acgcagaatg 1400

 caagtggaca aaaaaagagt gtatttggcc acagatgacc cttctttatt 1450

 aaaggaggca aaaacaaagt accccaatta tgaatttatt agtgataact 1500

 ctatttcctg gtcagctgga ctgcacaatc gatacacaga aaattcactt 1550

 cgtggagtga tcctggatat acattttctc tctcaggcag acttcctagt 1600

 gtgtactttt tcatcccagg tctgtcgagt tgcttatgaa attatgcaaa 1650

 cactacatcc tgatgcctct gcaaacttcc attctttaga tgacatctac 1700

 tattttgggg gccagaatgc ccacaatcaa attgccattt atgctcacca 1750

 accccgaact gcagatgaaa ttcccatgga acctggagat atcattggtg 1800

 tggctggaaa tcattgggat ggctattcta aaggtgtcaa caggaaattg 1850

 ggaaggacgg gcctatatcc ctcctacaaa gttcgagaga agatagaaac 1900

 ggtcaagtac cccacatatc ctgaggctga gaaataaagc tcagatggaa 1950

 gagataaacg accaaactca gttcgaccaa actcagttca aaccatttga 2000

 gccaaactgt agatgaagag ggctctgatc taacaaaata aggttatatg 2050

 agtagatact ctcagcacca agagcagctg ggaactgaca taggcttcaa 2100

 ttggtggaat tcctctttaa caagggctgc aatgccctca tacccatgca 2150

 cagtacaata atgtactcac atataacatg caaacaggtt gttttctact 2200

 ttgccccttt cagtatgtcc ccataagaca aacactgcca tattgtgtaa 2250

 tttaagtgac acagacattt tgtgtgagac ttaaaacatg gtgcctatat 2300

 ctgagagacc tgtgtgaact attgagaaga tcggaacagc tccttactct 2350

 gaggaagttg attcttattt gatggtggta ttgtgaccac tgaattcact 2400

 ccagtcaaca gattcagaat gagaatggac gtttggtttt tttttgtttt 2450

 tgtttttgtt ttttccttta taaggttgtc tgtttttttt ttttaaataa 2500

 ttgcatcagt tcattgacct catcattaat aagtgaagaa tacatcagaa 2550

 aataaaatat tccctctcca ttagaaaatt ttgtaaaaca atgccatgaa 2600

 caaattcttt agtactcaat gtttctggac attctctttg ataacaaaaa 2650

 ataaatttta aaaaggaaga aaaaaaaaaa aa 2682

<210> 1028
<211> 446
<212> PRT
<213> Homo sapien

<400> 1028
 Met Ala Ile Thr Val Ser Leu Val Asn Asn Lys Arg Lys Ile Val
   1               5                  10                  15

 Val Leu Ala Gln Pro Thr Thr Val Lys Arg Lys Arg Ile Thr Pro
                  20                  25                  30

 Tyr Lys Ser Ile Met Thr Asp Leu Tyr Tyr Leu Ser Gln Thr Asp
                  35                  40                  45

 Gly Ala Gly Asp Trp Arg Glu Lys Glu Ala Lys Asp Leu Thr Glu
                  50                  55                  60

 Leu Val Gln Arg Arg Ile Thr Tyr Leu Gln Asn Pro Lys Asp Cys
                  65                  70                  75

 Ser Lys Ala Lys Lys Leu Val Cys Asn Ile Asn Lys Gly Cys Gly
                  80                  85                  90

 Tyr Gly Cys Gln Leu His His Val Val Tyr Cys Phe Met Ile Ala
                  95                 100                 105

 Tyr Gly Thr Gln Arg Thr Leu Ile Leu Glu Ser Gln Asn Trp Arg
                 110                 115                 120

 Tyr Ala Thr Gly Gly Trp Glu Thr Val Phe Arg Pro Val Ser Glu
                 125                 130                 135

 Thr Cys Thr Asp Arg Ser Gly Ile Ser Thr Gly His Trp Ser Gly
                 140                 145                 150

 Glu Val Lys Asp Lys Asn Val Gln Val Val Glu Phe Pro Ile Val
                 155                 160                 165

 Asp Ser Leu His Pro Arg Pro Pro Tyr Leu Pro Leu Ala Val Pro
                 170                 175                 180

 Glu Asp Leu Ala Asp Arg Leu Val Arg Val His Gly Asp Pro Ala
                 185                 190                 195

 Val Trp Trp Val Ser Gln Phe Val Lys Tyr Leu Ile Arg Pro Gln
                 200                 205                 210

 Pro Trp Leu Glu Lys Glu Ile Glu Glu Ala Thr Lys Lys Leu Gly
                 215                 220                 225

 Phe Lys His Pro Val Ile Gly Val His Val Arg Arg Thr Asp Lys
                 230                 235                 240

 Val Gly Thr Glu Ala Ala Phe His Pro Ile Glu Glu Tyr Met Val
                 245                 250                 255

 His Val Glu Glu His Phe Gln Leu Leu Ala Arg Arg Met Gln Val
                 260                 265                 270

 Asp Lys Lys Arg Val Tyr Leu Ala Thr Asp Asp Pro Ser Leu Leu
                 275                 280                 285

 Lys Glu Ala Lys Thr Lys Tyr Pro Asn Tyr Glu Phe Ile Ser Asp
                 290                 295                 300

 Asn Ser Ile Ser Trp Ser Ala Gly Leu His Asn Arg Tyr Thr Glu
                 305                 310                 315

 Asn Ser Leu Arg Gly Val Ile Leu Asp Ile His Phe Leu Ser Gln
                 320                 325                 330

 Ala Asp Phe Leu Val Cys Thr Phe Ser Ser Gln Val Cys Arg Val
                 335                 340                 345

 Ala Tyr Glu Ile Met Gln Thr Leu His Pro Asp Ala Ser Ala Asn
                 350                 355                 360

 Phe His Ser Leu Asp Asp Ile Tyr Tyr Phe Gly Gly Gln Asn Ala
                 365                 370                 375

 His Asn Gln Ile Ala Ile Tyr Ala His Gln Pro Arg Thr Ala Asp
                 380                 385                 390

 Glu Ile Pro Met Glu Pro Gly Asp Ile Ile Gly Val Ala Gly Asn
                 395                 400                 405

 His Trp Asp Gly Tyr Ser Lys Gly Val Asn Arg Lys Leu Gly Arg
                 410                 415                 420

 Thr Gly Leu Tyr Pro Ser Tyr Lys Val Arg Glu Lys Ile Glu Thr
                 425                 430                 435

 Val Lys Tyr Pro Thr Tyr Pro Glu Ala Glu Lys
                 440                 445

<210> 1029
<211> 3592
<212> DNA
<213> Homo sapien

<400> 1029
 ggcggggggc gcacagagcc agaggggctt gcgagcggcg gctgagggac 50

 cgcggggagg gggcgccgag cggctccagc gcagagactc tcactgcacg 100

 ccggaggccc cttcctcgct ccgcccgcgc gaccgcgcgc cccagtcccg 150

 ccccgccccg ctaaccgccc cagacacagc gctcgccgag ggtcgcttgg 200

 accctgatct tacccgtggg caccctgcgc tctgcctgcc gcgaagaccg 250

 gctccccgac ccgcagaagt caggagagag ggtgaagcgg agcagcccga 300

 ggcggggcag cctcccggag cagcgccgcg cagagcccgg gacaatgggg 350

 ccgcggcggc tgctgctggt ggccgcctgc ttcagtctgt gcggcccgct 400

 gttgtctgcc cgcacccggg cccgcaggcc agaatcaaaa gcaacaaatg 450

 ccaccttaga tccccggtca tttcttctca ggaaccccaa tgataaatat 500

 gaaccatttt gggaggatga ggagaaaaat gaaagtgggt taactgaata 550

 cagattagtc tccatcaata aaagcagtcc tcttcaaaaa caacttcctg 600

 cattcatctc agaagatgcc tccggatatt tgaccagctc ctggctgaca 650

 ctctttgtcc catctgtgta caccggagtg tttgtagtca gcctcccact 700

 aaacatcatg gccatcgttg tgttcatcct gaaaatgaag gtcaagaagc 750

 cggcggtggt gtacatgctg cacctggcca cggcagatgt gctgtttgtg 800

 tctgtgctcc cctttaagat cagctattac ttttccggca gtgattggca 850

 gtttgggtct gaattgtgtc gcttcgtcac tgcagcattt tactgtaaca 900

 tgtacgcctc tatcttgctc atgacagtca taagcattga ccggtttctg 950

 gctgtggtgt atcccatgca gtccctctcc tggcgtactc tgggaagggc 1000

 ttccttcact tgtctggcca tctgggcttt ggccatcgca ggggtagtgc 1050

 ctctcgtcct caaggagcaa accatccagg tgcccgggct caacatcact 1100

 acctgtcatg atgtgctcaa tgaaaccctg ctcgaaggct actatgccta 1150

 ctacttctca gccttctctg ctgtcttctt ttttgtgccg ctgatcattt 1200

 ccacggtctg ttatgtgtct atcattcgat gtcttagctc ttccgcagtt 1250

 gccaaccgca gcaagaagtc ccgggctttg ttcctgtcag ctgctgtttt 1300

 ctgcatcttc atcatttgct tcggacccac aaacgtcctc ctgattgcgc 1350

 attactcatt cctttctcac acttccacca cagaggctgc ctactttgcc 1400

 tacctcctct gtgtctgtgt cagcagcata agctcgtgca tcgaccccct 1450

 aatttactat tacgcttcct ctgagtgcca gaggtacgtc tacagtatct 1500

 tatgctgcaa agaaagttcc gatcccagca gttataacag cagtgggcag 1550

 ttgatggcaa gtaaaatgga tacctgctct agtaacctga ataacagcat 1600

 atacaaaaag ctgttaactt aggaaaaggg actgctggga ggttaaaaag 1650

 aaaagtttat aaaagtgaat aacctgagga ttctattagt ccccacccaa 1700

 actttattga ttcacctcct aaaacaacag atgtacgact tgcatacctg 1750

 ctttttatgg gagctgtcaa gcatgtattt ttgtcaatta ccagaaagat 1800

 aacaggacga gatgacggtg ttattccaag ggaatattgc caatgctaca 1850

 gtaataaatg aatgtcactt ctggatatag ctaggtgaca tatacatact 1900

 tacatgtgtg tatatgtaga tgtatgcaca cacatatatt atttgcagtg 1950

 cagtatagaa taggcacttt aaaacactct ttccccgcac cccagcaatt 2000

 atgaaaataa tctctgattc cctgatttaa tatgcaaagt ctaggttggt 2050

 agagtttagc cctgaacatt tcatggtgtt catcaacagt gagagactcc 2100

 atagtttggg cttgtaccac ttttgcaaat aagtgtattt tgaaattgtt 2150

 tgacggcaag gtttaagtta ttaagaggta agacttagta ctatctgtgc 2200

 gtagaagttc tagtgttttc aattttaaac atatccaagt ttgaattcct 2250

 aaaattatgg aaacagatga aaagcctctg ttttgatatg ggtagtattt 2300

 tttacatttt acacactgta cacataagcc aaaactgagc ataagtcctc 2350

 tagtgaatgt aggctggctt tcagagtagg ctattcctga gagctgcatg 2400

 tgtccgcccc cgatggagga ctccaggcag cagacacatg ccagggccat 2450

 gtcagacaca gattggccag aaaccttcct gctgagcctc acagcagtga 2500

 gactggggcc actacatttg ctccatcctc ctgggattgg ctgtgaactg 2550

 atcatgttta tgagaaactg gcaaagcaga atgtgatatc ctaggaggta 2600

 atgaccatga aagacttctc tacccatctt aaaaacaacg aaagaaggca 2650

 tggacttctg gatgcccatc cactgggtgt aaacacatct agtagttgtt 2700

 ctgaaatgtc agttctgata tggaagcacc cattatgcgc tgtggccact 2750

 ccaataggtg ctgagtgtac agagtggaat aagacagaga cctgccctca 2800

 agagcaaagt agatcatgca tagagtgtga tgtatgtgta ataaatatgt 2850

 ttcacacaaa caaggcctgt cagctaaaga agtttgaaca tttgggttac 2900

 tatttcttgt ggttataact taatgaaaac aatgcagtac aggacatata 2950

 ttttttaaaa taagtctgat ttaattgggc actatttatt tacaaatgtt 3000

 ttgctcaata gattgctcaa atcaggtttt cttttaagaa tcaatcatgt 3050

 cagtctgctt agaaataaca gaagaaaata gaattgacat tgaaatctag 3100

 gaaaattatt ctataatttc catttactta agacttaatg agactttaaa 3150

 agcatttttt aacctcctaa gtatcaagta tagaaaatct tcatggaatt 3200

 cacaaagtaa tttggaaatt aggttgaaac atatctctta tcttacgaaa 3250

 aaatggtagc attttaaaca aaatagaaag ttgcaaggca aatgtttatt 3300

 taaaagagca ggccaggcgc ggtggctcac gcctgtaatc ccagcacttt 3350

 gggaggctga ggcgggtgga tcacgaggtc aggagatcga gaccatcctg 3400

 gctaacacgg tgaaacccgt ctctactaaa aatgcaaaaa aaattagccg 3450

 ggcgtggtgg caggcacctg tagtcccagc tactcgggag gctgaggcag 3500

 gagactggcg tgaacccagg aggcggacct tgtagtgagc cgagatcgcg 3550

 ccactgtgct ccagcctggg caacagagca agactccatc tc 3592

<210> 1030
<211> 425
<212> PRT
<213> Homo sapien

<400> 1030
 Met Gly Pro Arg Arg Leu Leu Leu Val Ala Ala Cys Phe Ser Leu
   1               5                  10                  15

 Cys Gly Pro Leu Leu Ser Ala Arg Thr Arg Ala Arg Arg Pro Glu
                  20                  25                  30

 Ser Lys Ala Thr Asn Ala Thr Leu Asp Pro Arg Ser Phe Leu Leu
                  35                  40                  45

 Arg Asn Pro Asn Asp Lys Tyr Glu Pro Phe Trp Glu Asp Glu Glu
                  50                  55                  60

 Lys Asn Glu Ser Gly Leu Thr Glu Tyr Arg Leu Val Ser Ile Asn
                  65                  70                  75

 Lys Ser Ser Pro Leu Gln Lys Gln Leu Pro Ala Phe Ile Ser Glu
                  80                  85                  90

 Asp Ala Ser Gly Tyr Leu Thr Ser Ser Trp Leu Thr Leu Phe Val
                  95                 100                 105

 Pro Ser Val Tyr Thr Gly Val Phe Val Val Ser Leu Pro Leu Asn
                 110                 115                 120

 Ile Met Ala Ile Val Val Phe Ile Leu Lys Met Lys Val Lys Lys
                 125                 130                 135

 Pro Ala Val Val Tyr Met Leu His Leu Ala Thr Ala Asp Val Leu
                 140                 145                 150

 Phe Val Ser Val Leu Pro Phe Lys Ile Ser Tyr Tyr Phe Ser Gly
                 155                 160                 165

 Ser Asp Trp Gln Phe Gly Ser Glu Leu Cys Arg Phe Val Thr Ala
                 170                 175                 180

 Ala Phe Tyr Cys Asn Met Tyr Ala Ser Ile Leu Leu Met Thr Val
                 185                 190                 195

 Ile Ser Ile Asp Arg Phe Leu Ala Val Val Tyr Pro Met Gln Ser
                 200                 205                 210

 Leu Ser Trp Arg Thr Leu Gly Arg Ala Ser Phe Thr Cys Leu Ala
                 215                 220                 225

 Ile Trp Ala Leu Ala Ile Ala Gly Val Val Pro Leu Val Leu Lys
                 230                 235                 240

 Glu Gln Thr Ile Gln Val Pro Gly Leu Asn Ile Thr Thr Cys His
                 245                 250                 255

 Asp Val Leu Asn Glu Thr Leu Leu Glu Gly Tyr Tyr Ala Tyr Tyr
                 260                 265                 270

 Phe Ser Ala Phe Ser Ala Val Phe Phe Phe Val Pro Leu Ile Ile
                 275                 280                 285

 Ser Thr Val Cys Tyr Val Ser Ile Ile Arg Cys Leu Ser Ser Ser
                 290                 295                 300

 Ala Val Ala Asn Arg Ser Lys Lys Ser Arg Ala Leu Phe Leu Ser
                 305                 310                 315

 Ala Ala Val Phe Cys Ile Phe Ile Ile Cys Phe Gly Pro Thr Asn
                 320                 325                 330

 Val Leu Leu Ile Ala His Tyr Ser Phe Leu Ser His Thr Ser Thr
                 335                 340                 345

 Thr Glu Ala Ala Tyr Phe Ala Tyr Leu Leu Cys Val Cys Val Ser
                 350                 355                 360

 Ser Ile Ser Ser Cys Ile Asp Pro Leu Ile Tyr Tyr Tyr Ala Ser
                 365                 370                 375

 Ser Glu Cys Gln Arg Tyr Val Tyr Ser Ile Leu Cys Cys Lys Glu
                 380                 385                 390

 Ser Ser Asp Pro Ser Ser Tyr Asn Ser Ser Gly Gln Leu Met Ala
                 395                 400                 405

 Ser Lys Met Asp Thr Cys Ser Ser Asn Leu Asn Asn Ser Ile Tyr
                 410                 415                 420

 Lys Lys Leu Leu Thr
                 425

<210> 1031
<211> 4104
<212> DNA
<213> Homo sapien

<400> 1031
 ctgcaggtta ttcagcgata gttatgacct cccggttacg tgcgttgggt 50

 ggaagaatta ataatatacg cacctcggag ttacccaaag agaaaactcg 100

 atcagaagtc atttgcagca tccacttttt agatggcgtg gtacagacct 150

 ttaaagttac taaacaagac actggccagg ttcttctgga tatggtgcac 200

 aaccacctgg gtgtgactga aaaggaatat tttggtttac agcatgatga 250

 cgactccgtg gactctccta gatggctgga agcaagcaaa gccatcagga 300

 agcagttaaa aggaggtttc ccctgtaccc tgcattttcg agtaagattt 350

 tttatacctg atcccaacac actgcagcaa gaacaaacca ggcacttgta 400

 tttcttacaa ctgaagatgg atatttgcga aggaaggtta acctgccctc 450

 ttaactcagc agtggttcta gcgtcctatg ccgtacaatc tcattttgga 500

 gactataatt cttccataca tcatccaggc tatctttccg atagtcactt 550

 tatacccgat caaaatgagg actttttaac aaaagtcgaa tctctgcatg 600

 agcagcacag tgggctaaaa caatcagaag cagaatcctg ctatatcaac 650

 atagcgcgga ccctcgactt ctatggagta gaactgcaca gtggtaggga 700

 tctgcacaat ttagacctaa tgattggaat tgcttccgcg ggtgttgctg 750

 tgtaccgaaa atacatttgc acaagtttct atccttgggt gaacattctc 800

 aaaatttctt tcaaaaggaa aaagttcttc atacatcagc gacagaaaca 850

 ggctgaatcc agggaacata ttgtggcctt caacatgctg aattaccgat 900

 cttgcaaaaa cttgtggaaa tcctgtgttg agcaccatac gttctttcag 950

 gcaaagaagc tactacctca ggaaaagaat gttctgtctc agtactggac 1000

 tatgggctct cggaacacca aaaagtcggt aaataaccaa tattgcaaaa 1050

 aggtgattgg cgggatggtg tggaacccag ccatgcggag atccttatca 1100

 gtggagcact tagaaaccaa gagtctgcct tctcgttccc ctcccattac 1150

 tcccaactgg cgaagtcctc ggctccggca cgaaatccga aagccacgcc 1200

 actcttctgc agataacctt gcaaatgaaa tgacctacat cacggaaacg 1250

 gaagatgtat tttacacgta caagggctct ctggcccctc aagacagcga 1300

 ttctgaagtt tctcagaacc gaagcccgca ccaagagagt ttatccgaga 1350

 acaatccggc acaaagctac ctgacccaga agtcatccag ttctgtgtct 1400

 ccatcttcaa atgctccagg ctcctgctca cctgacggcg ttgatcagca 1450

 gctcttagat gacttccaca gggtgaccaa agggggctcc accgaggacg 1500

 ccagccagta ctactgtgac aagaatgata atggtgacag ctacttagtc 1550

 ttgatccgta tcacaccaga tgaagatgga aaatttggat ttaatcttaa 1600

 gggaggagtg gatcaaaaga tgcctcttgt ggtatcaagg ataaacccag 1650

 agtcacctgc ggacacctgc attcctaagc tgaacgaagg ggatcaaatc 1700

 gtgttaatca atggccggga catctcagaa cacacgcatg accaagtggt 1750

 gatgttcatc aaagccagcc gggagtccca ctcacgggag ctggccctgg 1800

 tgatcaggag gagagctgtc cgctcatttg ctgacttcaa gtctgaagat 1850

 gaactgaacc agcttttccc cgaagccatt ttccccatgt gtccggaggg 1900

 tggggacact ttggagggat ccatggcaca gctaaagaag ggcctcgaaa 1950

 gcgggacggt gctgatccag tttgagcaac tctacagaaa aaagccaggt 2000

 ttggccatca cgtttgcaaa gctgcctcaa aatttggaca aaaaccgata 2050

 taaagatgtg ctgccttatg acaccacccg ggtattattg cagggaaatg 2100

 aagattatat taatgcaagt tacgtgaaca tggaaattcc tgctgctaac 2150

 cttgtgaaca agtacatcgc cactcagggg cccctgccgc atacctgtgc 2200

 acagttttgg caggttgtct gggatcagaa gttgtcactc attgtcatgt 2250

 tgacgactct cacagaacga gggcggacca aatgtcacca gtactggcca 2300

 gatccccccg acgtcatgaa ccacggcggc tttcacatcc agtgtcagtc 2350

 agaggactgc accatcgcct atgtgtcccg agaaatgctg gtcacaaaca 2400

 cccagaccgg ggaagaacac acagtgacac atctccagta cgtcgcatgg 2450

 cctgaccacg gtgtgcccga tgactcctcc gactttctgg aatttgtaaa 2500

 ctatgtgagg tctctgagag tggacagcga gcctctccta gttcactgca 2550

 gtgctggaat aggtcgaacc ggtgtgttgg tcactatgga aacagccatg 2600

 tgcctaactg agaggaacct gcccatttac ccactggata ttgtccgaaa 2650

 aatgcgagac cagcgcgcca tgatggtgca gacatcaagc cagtacaagt 2700

 ttgtgtgtga agcgattctt cgtgtgtatg aagaaggttt agtccaaatg 2750

 ctggatccta gttaagacaa ctgtgaaaaa gttcattcct ctttcccaag 2800

 ggcatcctcc ttgaaagagg aggacagacc tctctggaag cagcaagagg 2850

 aaccagtagc tgtgggaaag gaatgggcac ctctgaaccc aggcacttta 2900

 aacttctata gaaaagatat cgtgtacata ggaactggtg tagataagca 2950

 tgcaattatg gcatcattta ggcctgtatt tctatggaaa gatacaaaaa 3000

 ggatctcagt ttggggcctg tcctaatgcc ttcttcccta acatcaccac 3050

 acacacccct gtcggcatcc tggagcaatt gagaccggac acccacagag 3100

 ctgttgtcct cccagcaaca agatggtgtg gttatcttgg gtcatttgga 3150

 tgttttgttt gtttctgtgt gtcagactgt aagggctgag ctttctgtgc 3200

 ttctaggtgg agctggaaca attcagattc acccgccctg atgctaagga 3250

 aaccctgacg tatgtactag atggcagggc actgggggtc aggctgaagg 3300

 ctgagcaaca cctctctgcc ctccctccct ttgtcccatc tcccagcgac 3350

 ttccaatatt catgtttctg agaattgtgt ccctcttcag gttccctctt 3400

 ggtgcctaac ctggattagt aatgtgcatt caggtgaatt ttcagctgag 3450

 gctctgagaa ctggtactct cagtgtgttc tggtcatctt gtggcttagt 3500

 tgtagaagca ggtgtgtctc ttgcctctgc ttgcctccta ctgcacactc 3550

 agcacccagg actggaatca ccgactactg aatctcctac atgtattgct 3600

 gctacttcaa gctcctccac ttgaaacctt atgattttcc caaggggaga 3650

 tgggacagtg tcatctaaat attccgaatg tttggccttc tgagaaaaga 3700

 gcttctagta attgaaccat gggaaaccca gcttctggag ggttggccgt 3750

 ggggctgtgt acatgtgtgt gcccaggggt gagtgtttct caggattcct 3800

 aacgattcaa attaccgttg agtatatata aagaatgagt ctctgtatgg 3850

 aagaacaaat gtgtgcattc acccccagtc acaatggtct ccattgcatt 3900

 tcaaaggaga ggatcagact atctgaatat aaacacaatc tgatgttaat 3950

 ttattctaag aacaccatca ttttgattgt cctaaagaat tctgcctttg 4000

 tgaataccgt gttaaatttt tttaaatttg tgacaggatt gtagcaaatt 4050

 attatttaag gaaaataaat tgtgtaaaca tttaaaaaaa aaaaaaaaaa 4100

 aaaa 4104

<210> 1032
<211> 913
<212> PRT
<213> Homo sapien

<400> 1032
 Met Thr Ser Arg Leu Arg Ala Leu Gly Gly Arg Ile Asn Asn Ile
   1               5                  10                  15

 Arg Thr Ser Glu Leu Pro Lys Glu Lys Thr Arg Ser Glu Val Ile
                  20                  25                  30

 Cys Ser Ile His Phe Leu Asp Gly Val Val Gln Thr Phe Lys Val
                  35                  40                  45

 Thr Lys Gln Asp Thr Gly Gln Val Leu Leu Asp Met Val His Asn
                  50                  55                  60

 His Leu Gly Val Thr Glu Lys Glu Tyr Phe Gly Leu Gln His Asp
                  65                  70                  75

 Asp Asp Ser Val Asp Ser Pro Arg Trp Leu Glu Ala Ser Lys Ala
                  80                  85                  90

 Ile Arg Lys Gln Leu Lys Gly Gly Phe Pro Cys Thr Leu His Phe
                  95                 100                 105

 Arg Val Arg Phe Phe Ile Pro Asp Pro Asn Thr Leu Gln Gln Glu
                 110                 115                 120

 Gln Thr Arg His Leu Tyr Phe Leu Gln Leu Lys Met Asp Ile Cys
                 125                 130                 135

 Glu Gly Arg Leu Thr Cys Pro Leu Asn Ser Ala Val Val Leu Ala
                 140                 145                 150

 Ser Tyr Ala Val Gln Ser His Phe Gly Asp Tyr Asn Ser Ser Ile
                 155                 160                 165

 His His Pro Gly Tyr Leu Ser Asp Ser His Phe Ile Pro Asp Gln
                 170                 175                 180

 Asn Glu Asp Phe Leu Thr Lys Val Glu Ser Leu His Glu Gln His
                 185                 190                 195

 Ser Gly Leu Lys Gln Ser Glu Ala Glu Ser Cys Tyr Ile Asn Ile
                 200                 205                 210

 Ala Arg Thr Leu Asp Phe Tyr Gly Val Glu Leu His Ser Gly Arg
                 215                 220                 225

 Asp Leu His Asn Leu Asp Leu Met Ile Gly Ile Ala Ser Ala Gly
                 230                 235                 240

 Val Ala Val Tyr Arg Lys Tyr Ile Cys Thr Ser Phe Tyr Pro Trp
                 245                 250                 255

 Val Asn Ile Leu Lys Ile Ser Phe Lys Arg Lys Lys Phe Phe Ile
                 260                 265                 270

 His Gln Arg Gln Lys Gln Ala Glu Ser Arg Glu His Ile Val Ala
                 275                 280                 285

 Phe Asn Met Leu Asn Tyr Arg Ser Cys Lys Asn Leu Trp Lys Ser
                 290                 295                 300

 Cys Val Glu His His Thr Phe Phe Gln Ala Lys Lys Leu Leu Pro
                 305                 310                 315

 Gln Glu Lys Asn Val Leu Ser Gln Tyr Trp Thr Met Gly Ser Arg
                 320                 325                 330

 Asn Thr Lys Lys Ser Val Asn Asn Gln Tyr Cys Lys Lys Val Ile
                 335                 340                 345

 Gly Gly Met Val Trp Asn Pro Ala Met Arg Arg Ser Leu Ser Val
                 350                 355                 360

 Glu His Leu Glu Thr Lys Ser Leu Pro Ser Arg Ser Pro Pro Ile
                 365                 370                 375

 Thr Pro Asn Trp Arg Ser Pro Arg Leu Arg His Glu Ile Arg Lys
                 380                 385                 390

 Pro Arg His Ser Ser Ala Asp Asn Leu Ala Asn Glu Met Thr Tyr
                 395                 400                 405

 Ile Thr Glu Thr Glu Asp Val Phe Tyr Thr Tyr Lys Gly Ser Leu
                 410                 415                 420

 Ala Pro Gln Asp Ser Asp Ser Glu Val Ser Gln Asn Arg Ser Pro
                 425                 430                 435

 His Gln Glu Ser Leu Ser Glu Asn Asn Pro Ala Gln Ser Tyr Leu
                 440                 445                 450

 Thr Gln Lys Ser Ser Ser Ser Val Ser Pro Ser Ser Asn Ala Pro
                 455                 460                 465

 Gly Ser Cys Ser Pro Asp Gly Val Asp Gln Gln Leu Leu Asp Asp
                 470                 475                 480

 Phe His Arg Val Thr Lys Gly Gly Ser Thr Glu Asp Ala Ser Gln
                 485                 490                 495

 Tyr Tyr Cys Asp Lys Asn Asp Asn Gly Asp Ser Tyr Leu Val Leu
                 500                 505                 510

 Ile Arg Ile Thr Pro Asp Glu Asp Gly Lys Phe Gly Phe Asn Leu
                 515                 520                 525

 Lys Gly Gly Val Asp Gln Lys Met Pro Leu Val Val Ser Arg Ile
                 530                 535                 540

 Asn Pro Glu Ser Pro Ala Asp Thr Cys Ile Pro Lys Leu Asn Glu
                 545                 550                 555

 Gly Asp Gln Ile Val Leu Ile Asn Gly Arg Asp Ile Ser Glu His
                 560                 565                 570

 Thr His Asp Gln Val Val Met Phe Ile Lys Ala Ser Arg Glu Ser
                 575                 580                 585

 His Ser Arg Glu Leu Ala Leu Val Ile Arg Arg Arg Ala Val Arg
                 590                 595                 600

 Ser Phe Ala Asp Phe Lys Ser Glu Asp Glu Leu Asn Gln Leu Phe
                 605                 610                 615

 Pro Glu Ala Ile Phe Pro Met Cys Pro Glu Gly Gly Asp Thr Leu
                 620                 625                 630

 Glu Gly Ser Met Ala Gln Leu Lys Lys Gly Leu Glu Ser Gly Thr
                 635                 640                 645

 Val Leu Ile Gln Phe Glu Gln Leu Tyr Arg Lys Lys Pro Gly Leu
                 650                 655                 660

 Ala Ile Thr Phe Ala Lys Leu Pro Gln Asn Leu Asp Lys Asn Arg
                 665                 670                 675

 Tyr Lys Asp Val Leu Pro Tyr Asp Thr Thr Arg Val Leu Leu Gln
                 680                 685                 690

 Gly Asn Glu Asp Tyr Ile Asn Ala Ser Tyr Val Asn Met Glu Ile
                 695                 700                 705

 Pro Ala Ala Asn Leu Val Asn Lys Tyr Ile Ala Thr Gln Gly Pro
                 710                 715                 720

 Leu Pro His Thr Cys Ala Gln Phe Trp Gln Val Val Trp Asp Gln
                 725                 730                 735

 Lys Leu Ser Leu Ile Val Met Leu Thr Thr Leu Thr Glu Arg Gly
                 740                 745                 750

 Arg Thr Lys Cys His Gln Tyr Trp Pro Asp Pro Pro Asp Val Met
                 755                 760                 765

 Asn His Gly Gly Phe His Ile Gln Cys Gln Ser Glu Asp Cys Thr
                 770                 775                 780

 Ile Ala Tyr Val Ser Arg Glu Met Leu Val Thr Asn Thr Gln Thr
                 785                 790                 795

 Gly Glu Glu His Thr Val Thr His Leu Gln Tyr Val Ala Trp Pro
                 800                 805                 810

 Asp His Gly Val Pro Asp Asp Ser Ser Asp Phe Leu Glu Phe Val
                 815                 820                 825

 Asn Tyr Val Arg Ser Leu Arg Val Asp Ser Glu Pro Leu Leu Val
                 830                 835                 840

 His Cys Ser Ala Gly Ile Gly Arg Thr Gly Val Leu Val Thr Met
                 845                 850                 855

 Glu Thr Ala Met Cys Leu Thr Glu Arg Asn Leu Pro Ile Tyr Pro
                 860                 865                 870

 Leu Asp Ile Val Arg Lys Met Arg Asp Gln Arg Ala Met Met Val
                 875                 880                 885

 Gln Thr Ser Ser Gln Tyr Lys Phe Val Cys Glu Ala Ile Leu Arg
                 890                 895                 900

 Val Tyr Glu Glu Gly Leu Val Gln Met Leu Asp Pro Ser
                 905                 910

<210> 1033
<211> 3769
<212> DNA
<213> Homo sapien

<400> 1033
 aaaagatttt aacaagtata aaaaattctc ataggaatta aatgtagtct 50

 ccctgtgtca gactgctctt tcatagtata actttaaatc ttttcttcaa 100

 cttgagtctt tgaagatagt tttaattctg cttgtgacat taaaagatta 150

 tttgggccag ttatagctta ttaggtgttg aagagaccaa ggttgcaagg 200

 ccaggccctg tgtgaacctt tgagctttca tagagagttt cacagcatgg 250

 actgtgtccc cacggtcatc cagtgttgtc atgcattggt tagtcaaaat 300

 ggggagggac tagggcagtt tggatagctc aacaagatac aatctcactc 350

 tgtggtggtc ctgctgacaa atcaagagca ttgcttttgt ttcttaagaa 400

 aacaaactct tttttaaaaa ttacttttaa atattaactc aaaagttgag 450

 attttggggt ggtggtgtgc caagacatta attttttttt aaacaatgaa 500

 gtgaaaaagt tttacaatct ctaggtttgg ctagttctct taacactggt 550

 taaattaaca ttgcataaac acttttcaag tctgatccat atttaataat 600

 gctttaaaat aaaaataaaa acaatccttt tgataaattt aaaatgttac 650

 ttattttaaa ataaatgaag tgagatggca tggtgaggtg aaagtatcac 700

 tggactagga agaaggtgac ttaggttcta gataggtgtc ttttaggact 750

 ctgattttga ggacatcact tactatccat ttcttcatgt taaaagaagt 800

 catctcaaac tcttagtttt ttttttttac aactatgtga tttatattcc 850

 atttacataa ggatacactt atttgtcaag ctcagcacaa tctgtaaatt 900

 tttaacctat gttacaccat cttcagtgcc agtcttgggc aaaattgtgc 950

 aagaggtgaa gtttatattt gaatatccat tctcgtttta ggactcttct 1000

 tccatattag tgtcatcttg cctccctacc ttccacatgc cccatgactt 1050

 gatgcagttt taatacttgt aattccccta accataagat ttactgctgc 1100

 tgtggatatc tccatgaagt tttcccactg agtcacatca gaaatgccct 1150

 acatcttatt tcctcagggc tcaagagaat ctgacagata ccataaaggg 1200

 atttgaccta atcactaatt ttcaggtggt ggctgatgct ttgaacatct 1250

 ctttgctgcc caatccatta gcgacagtag gatttttcaa acctggtatg 1300

 aatagacaga accctatcca gtggaaggag aatttaataa agatagtgct 1350

 gaaagaattc cttaggtaat ctataactag gactgctcct ggtaacagta 1400

 atacattcca ttgttttagt aaccagaaat cttcatgcaa tgaaaaatac 1450

 tttaattcat gaagcttact tttttttttt ttggtgtcag agtctcgctc 1500

 ttgtcaccca ggctggaatg cagtggcgcc atctcagctc actgcaacct 1550

 ccatctccca ggttcaagcg attctcgtgc ctcggcctcc tgagtagctg 1600

 ggattacagg cgtgtgccac tacactcaac taatttttgt atttttagga 1650

 gagacggggt ttcaccctgt tggccaggct ggtctcgaac tcctgacctc 1700

 aagtgattca cccaccttgg cctcataaac ctgttttgca gaactcattt 1750

 attcagcaaa tatttattga gtgcctacca gatgccagtc accgcacaag 1800

 gcactgggta tatggtatcc ccaaacaaga gacataatcc cggtccttag 1850

 gtagtgctag tgtggtctgt aatatcttac taaggccttt ggtatacgac 1900

 ccagagataa cacgatgcgt attttagttt tgcaaagaag gggtttggtc 1950

 tctgtgccag ctctataatt gttttgctac gattccactg aaactcttcg 2000

 atcaagctac tttatgtaaa tcacttcatt gttttaaagg aataaacttg 2050

 attatattgt ttttttattt ggcataactg tgattctttt aggacaatta 2100

 ctgtacacat taaggtgtat gtcagatatt catattgacc caaatgtgta 2150

 atattccagt tttctctgca taagtaatta aaatatactt aaaaattaat 2200

 agttttatct gggtacaaat aaacaggtgc ctgaactagt tcacagacaa 2250

 ggaaacttct atgtaaaaat cactatgatt tctgaattgc tatgtgaaac 2300

 tacagatctt tggaacactg tttaggtagg gtgttaagac ttacacagta 2350

 cctcgtttct acacagagaa agaaatggcc atacttcagg aactgcagtg 2400

 cttatgaggg gatatttagg cctcttgaat ttttgatgta gatgggcatt 2450

 tttttaaggt agtggttaat tacctttatg tgaactttga atggtttaac 2500

 aaaagatttg tttttgtaga gattttaaag ggggagaatt ctagaaataa 2550

 atgttaccta attattacag ccttaaagac aaaaatcctt gttgaagttt 2600

 ttttaaaaaa agctaaatta catagactta ggcattaaca tgtttgtgga 2650

 agaatatagc agacgtatat tgtatcattt gagtgaatgt tcccaagtag 2700

 gcattctagg ctctatttaa ctgagtcaca ctgcatagga atttagaacc 2750

 taacttttat aggttatcaa aactgttgtc accattgcac aattttgtcc 2800

 taatatatac atagaaactt tgtggggcat gttaagttac agtttgcaca 2850

 agttcatctc atttgtattc cattgatttt ttttttcttc taaacatttt 2900

 ttcttcaaac agtatataac tttttttagg ggattttttt ttagacagca 2950

 aaaactatct gaagatttcc atttgtcaaa aagtaatgat ttcttgataa 3000

 ttgtgtagta atgtttttta gaacccagca gttaccttaa agctgaattt 3050

 atatttagta acttctgtgt taatactgga tagcatgaat tctgcattga 3100

 gaaactgaat agctgtcata aaatgaaact ttctttctaa agaaagatac 3150

 tcacatgagt tcttgaagaa tagtcataac tagattaaga tctgtgtttt 3200

 agtttaatag tttgaagtgc ctgtttggga taatgatagg taatttagat 3250

 gaatttaggg gaaaaaaaag ttatctgcag atatgttgag ggcccatctc 3300

 tccccccaca cccccacaga gctaactggg ttacagtgtt ttatccgaaa 3350

 gtttccaatt ccactgtctt gtgttttcat gttgaaaata cttttgcatt 3400

 tttcctttga gtgccaattt cttactagta ctatttctta atgtaacatg 3450

 tttacctgga atgtatttta actatttttg tatagtgtaa actgaaacat 3500

 gcacattttt tgtacattgt gctttctttt gtgggacata tgcagtgtga 3550

 tccagttgtt ttccatcatt tggttgcgct gacctaggaa tgttggtcat 3600

 atcaaacatt aaaaatgacc actcttttaa ttgaaattaa cttttaaatg 3650

 tttataggag tatgtgctgt gaagtgatct aaaatttgta atatttttgt 3700

 catgaactgt actactccta attattgtaa tgtaataaaa atagttacag 3750

 tgacaaaaaa aaaaaaaaa 3769

<210> 1034
<211> 62
<212> PRT
<213> Homo sapien

<400> 1034
 Met Gln Trp Arg His Leu Ser Ser Leu Gln Pro Pro Ser Pro Arg
   1               5                  10                  15

 Phe Lys Arg Phe Ser Cys Leu Gly Leu Leu Ser Ser Trp Asp Tyr
                  20                  25                  30

 Arg Arg Val Pro Leu His Ser Thr Asn Phe Cys Ile Phe Arg Arg
                  35                  40                  45

 Asp Gly Val Ser Pro Cys Trp Pro Gly Trp Ser Arg Thr Pro Asp
                  50                  55                  60

 Leu Lys


<210> 1035
<211> 2126
<212> DNA
<213> Homo sapien

<400> 1035
 gtaaggccgt tttcttttcc cattcgctca tctgccagga aaagggactt 50

 gccgttggcg cttcggcctc ttgttcattg agaaaaaaga ggaaatactc 100

 cgcgtgcgct tgtagaaggg gagtcgtctc cagctccgaa ccccggagtg 150

 ttcatcagcg gggaatctgg ctccgaattc tctttttttc tcccgccgat 200

 tgctcggaag ttggtctaaa gcagaggttg gaaagaaagg aaaaaagttt 250

 gcatcgagac tggatttatt tgcacatcgc agaaagaaga gaatccaagg 300

 gagaggggtt ggtgcaaagc cgcgatcacg gagttcagat gtgttctaag 350

 cctgctggag tgaccacact tccaagacct gatggaggcc agagctcaga 400

 gtggcaacgg gtcgcagccc ttgctgcaga cgccccgtga cggtggcaga 450

 cagcgtgggg agcccgaccc cagagacgcc ctcacccagc aggtacatgt 500

 cttgtctctg gatcagatca gagccatccg aaacaccaat gagtacacag 550

 aggggcctac tgtcgtccca agacctgggc tcaagcctgc tcctcgcccc 600

 tccactcagc acaaacacga gagactccac ggtctgcctg agcaccgcca 650

 gcctcctagg ctccagcact cgcaggtcca ttcttctgca cgagcccctc 700

 tgtccagatc cataagcacg gtcagctcag ggtcgcggag cagtacgagg 750

 acaagtacca gcagcagctc ctctgaacag agactgctag gatcatcctt 800

 ctcctccggg cctgttgctg atggcataat ccgggtgcaa cccaaatctg 850

 agctcaagcc aggtgagctt aagccactga gcaaggaaga tttgggcctg 900

 cacgcctaca ggtgtgagga ctgtggcaag tgcaaatgta aggagtgcac 950

 ctacccaagg cctctgccat cagactggat ctgcgacaag cagtgccttt 1000

 gctcggccca gaacgtgatt gactatggga cttgtgtatg ctgtgtgaaa 1050

 ggtctcttct atcactgttc taatgatgat gaggacaact gtgctgacaa 1100

 cccatgttct tgcagccagt ctcactgttg tacacgatgg tcagccatgg 1150

 gtgtcatgtc cctctttttg ccttgtttat ggtgttacct tccagccaag 1200

 ggttgcctta aattgtgcca ggggtgttat gaccgggtta acaggcctgg 1250

 ttgccgctgt aaaaactcaa acacagtttg ctgcaaagtt cccactgtcc 1300

 cccctaggaa ctttgaaaaa ccaacatagc atcattaatc aggaatatta 1350

 cagtaatgag gattttttct ttcttttttt aatacacata tgcaaccaac 1400

 taaacagtta taatcttggc actgttaata gaaaggtggg atagtctttg 1450

 ctgtttgcgg tgaaatgctt tttgtccatg tgccgtttta actgatatgc 1500

 ttgttagaac tcagctaatg gagctcaaag tatgagatac agaacttggt 1550

 gacccatgta ttgcataagc taaagcaaca cagacactcc taggcaaagt 1600

 ttttgtttgt gaatagtact tgcaaaactt gtaaattagc agatgacttt 1650

 tttccattgt tttctccaga gagaatgtgc tatatttttg tatatacaat 1700

 aatatttgca actgtgaaaa acaagttgtg ccatactaca tggcacagac 1750

 acaaaatatt atactaatat gttgtacatt cggaagaatg tgaatcaatc 1800

 agtatgtttt tagattgtat tttgccttac agaaagcctt tattgtaaga 1850

 ctctgatttc cctttggact tcatgtatat tgtacagtta cagtaaaatt 1900

 caacctttat tttctaattt tttcaacata ttgtttagtg taaagaatat 1950

 ttatttgaag ttttattatt ttataaaaaa gaatatttat tttaagaggc 2000

 atcttacaaa ttttgcccct tttatgagga tgtgatagtt gctgcaaatg 2050

 aggggttaca gatgcatatg tccaatataa aatagaaaat atattaacgt 2100

 ttgaaattaa aaaaaaaaaa aaaaaa 2126

<210> 1036
<211> 315
<212> PRT
<213> Homo sapien

<400> 1036
 Met Glu Ala Arg Ala Gln Ser Gly Asn Gly Ser Gln Pro Leu Leu
   1               5                  10                  15

 Gln Thr Pro Arg Asp Gly Gly Arg Gln Arg Gly Glu Pro Asp Pro
                  20                  25                  30

 Arg Asp Ala Leu Thr Gln Gln Val His Val Leu Ser Leu Asp Gln
                  35                  40                  45

 Ile Arg Ala Ile Arg Asn Thr Asn Glu Tyr Thr Glu Gly Pro Thr
                  50                  55                  60

 Val Val Pro Arg Pro Gly Leu Lys Pro Ala Pro Arg Pro Ser Thr
                  65                  70                  75

 Gln His Lys His Glu Arg Leu His Gly Leu Pro Glu His Arg Gln
                  80                  85                  90

 Pro Pro Arg Leu Gln His Ser Gln Val His Ser Ser Ala Arg Ala
                  95                 100                 105

 Pro Leu Ser Arg Ser Ile Ser Thr Val Ser Ser Gly Ser Arg Ser
                 110                 115                 120

 Ser Thr Arg Thr Ser Thr Ser Ser Ser Ser Ser Glu Gln Arg Leu
                 125                 130                 135

 Leu Gly Ser Ser Phe Ser Ser Gly Pro Val Ala Asp Gly Ile Ile
                 140                 145                 150

 Arg Val Gln Pro Lys Ser Glu Leu Lys Pro Gly Glu Leu Lys Pro
                 155                 160                 165

 Leu Ser Lys Glu Asp Leu Gly Leu His Ala Tyr Arg Cys Glu Asp
                 170                 175                 180

 Cys Gly Lys Cys Lys Cys Lys Glu Cys Thr Tyr Pro Arg Pro Leu
                 185                 190                 195

 Pro Ser Asp Trp Ile Cys Asp Lys Gln Cys Leu Cys Ser Ala Gln
                 200                 205                 210

 Asn Val Ile Asp Tyr Gly Thr Cys Val Cys Cys Val Lys Gly Leu
                 215                 220                 225

 Phe Tyr His Cys Ser Asn Asp Asp Glu Asp Asn Cys Ala Asp Asn
                 230                 235                 240

 Pro Cys Ser Cys Ser Gln Ser His Cys Cys Thr Arg Trp Ser Ala
                 245                 250                 255

 Met Gly Val Met Ser Leu Phe Leu Pro Cys Leu Trp Cys Tyr Leu
                 260                 265                 270

 Pro Ala Lys Gly Cys Leu Lys Leu Cys Gln Gly Cys Tyr Asp Arg
                 275                 280                 285

 Val Asn Arg Pro Gly Cys Arg Cys Lys Asn Ser Asn Thr Val Cys
                 290                 295                 300

 Cys Lys Val Pro Thr Val Pro Pro Arg Asn Phe Glu Lys Pro Thr
                 305                 310                 315

<210> 1037
<211> 2514
<212> DNA
<213> Homo sapien

<400> 1037
 ggcacgaggg ctgagcgccg gaggagcgta ggcagggcag cgctggcgcc 50

 agcggcgaca ggagccgcgc gaccggcaaa aatacacggg aggccgtcgc 100

 cgaaaagagt ccgcggtcct ctctcgtaaa cacactctcc tccaccggcg 150

 cctccccctc cgctctgcgc gccgcccggc tgggcgcccg aggccgctcc 200

 gactgctatg tgaccgcgag gctgcgggag gaaggggaca gggaagaaga 250

 ggctctcccg cgggagccct tgaggaccaa gtttgcggcc acttctgcag 300

 gcgtcccttc ttagctctcg cctgcccctt tctgcagcct aggcggccca 350

 ggttctcttc tcttcctcgc gcgcccagcc gcctcggttc ccggcgacca 400

 tggtgacgat ggaggagctg cgggagatgg actgcagtgt gctcaaaagg 450

 ctgatgaacc gggacgagaa tggcggcggc gcgggcggca gcggcagcca 500

 cggcaccctg gggctgccga gcggcggcaa gtgcctgctg ctggactgca 550

 gaccgttcct ggcgcacagc gcgggctaca tcctaggttc ggtcaacgtg 600

 cgctgtaaca ccatcgtgcg gcggcgggct aagggctccg tgagcctgga 650

 gcagatcctg cccgccgagg aggaggtacg cgcccgcttg cgctccggcc 700

 tctactcggc ggtcatcgtc tacgacgagc gcagcccgcg cgccgagagc 750

 ctccgcgagg acagcaccgt gtcgctggtg gtgcaggcgc tgcgccgcaa 800

 cgccgagcgc accgacatct gcctgctcaa aggcggctat gagaggtttt 850

 cctccgagta cccagaattc tgttctaaaa ccaaggccct ggcagccatc 900

 ccacccccgg ttccccccag cgccacagag cccttggacc tgggctgcag 950

 ctcctgtggg accccactac acgaccaggg gggtcctgtg gagatccttc 1000

 ccttcctcta cctcggcagt gcctaccatg ctgcccggag agacatgctg 1050

 gacgccctgg gcatcacggc tctgttgaat gtctcctcgg actgcccaaa 1100

 ccactttgaa ggacactatc agtacaagtg catcccagtg gaagataacc 1150

 acaaggccga catcagctcc tggttcatgg aagccataga gtacatcgat 1200

 gccgtgaagg actgccgtgg gcgcgtgctg gtgcactgcc aggcgggcat 1250

 ctcgcggtcg gccaccatct gcctggccta cctgatgatg aagaaacggg 1300

 tgaggctgga ggaggccttc gagttcgtta agcagcgccg cagcatcatc 1350

 tcgcccaact tcagcttcat ggggcagctg ctgcagttcg agtcccaggt 1400

 gctggccacg tcctgtgctg cggaggctgc tagcccctcg ggacccctgc 1450

 gggagcgggg caagaccccc gccaccccca cctcgcagtt cgtcttcagc 1500

 tttccggtct ccgtgggcgt gcactcggcc cccagcagcc tgccctacct 1550

 gcacagcccc atcaccacct ctcccagctg ttagagccgc cctgggggcc 1600

 ccagaaccag agctggctcc cagcaagggt aggacgggcc gcatgcggca 1650

 gaaagttggg actgagcagc tgggagcagg cgaccgagct ccttccccat 1700

 catttctcct tggccaacga cgaggccagc cagaatggca ataaggactc 1750

 cgaatacata ataaaagcaa acagaacact ccaacttaga gcaataaccg 1800

 gtgccgcagc agccagggaa gaccttggtt tggtttatgt gtcagtttca 1850

 cttttccgat agaaatttct tacctcattt ttttaagcag taaggcttga 1900

 agtgatgaaa cccacagatc ctagcaaatg tgcccaacca gctttactaa 1950

 agggggagga agggagggca aagggatgag aagacaagtt tcccagaagt 2000

 gcctggttct gggtacttgt ccctttgttg tcgttgttgt agttaaagga 2050

 atttcatttt taaaagaaat cttcgaaggt gtggttttca tttctcagtc 2100

 accaacagat gaataattat gcttaataat aaagtattta ttaagacttt 2150

 cttcagagta tgaaagtaca aaaagtctag ttacagtgga tttagaatat 2200

 atttatgttg atgtcaaaca gctgagcacc gtagcatgca gatgtcaagg 2250

 cagttaggaa gtaaatggtg tcttgtagat atgtgcaagg tagcatgatg 2300

 agcaacttga gtttgttgcc actgagaagc aggcgggttg ggtgggagga 2350

 ggaagaaagg gaagaattag gtttgaattg ctttttaaaa aaaaaagaaa 2400

 agaaaaagac agcatctcac tatgttgcca aggctcatct tgagaagcag 2450

 gcgggttggg tgggaggagg aagaaaggga agaattaggt ttgaattgct 2500

 tttttaaaaa aaaa 2514

<210> 1038
<211> 394
<212> PRT
<213> Homo sapien

<400> 1038
 Met Val Thr Met Glu Glu Leu Arg Glu Met Asp Cys Ser Val Leu
   1               5                  10                  15

 Lys Arg Leu Met Asn Arg Asp Glu Asn Gly Gly Gly Ala Gly Gly
                  20                  25                  30

 Ser Gly Ser His Gly Thr Leu Gly Leu Pro Ser Gly Gly Lys Cys
                  35                  40                  45

 Leu Leu Leu Asp Cys Arg Pro Phe Leu Ala His Ser Ala Gly Tyr
                  50                  55                  60

 Ile Leu Gly Ser Val Asn Val Arg Cys Asn Thr Ile Val Arg Arg
                  65                  70                  75

 Arg Ala Lys Gly Ser Val Ser Leu Glu Gln Ile Leu Pro Ala Glu
                  80                  85                  90

 Glu Glu Val Arg Ala Arg Leu Arg Ser Gly Leu Tyr Ser Ala Val
                  95                 100                 105

 Ile Val Tyr Asp Glu Arg Ser Pro Arg Ala Glu Ser Leu Arg Glu
                 110                 115                 120

 Asp Ser Thr Val Ser Leu Val Val Gln Ala Leu Arg Arg Asn Ala
                 125                 130                 135

 Glu Arg Thr Asp Ile Cys Leu Leu Lys Gly Gly Tyr Glu Arg Phe
                 140                 145                 150

 Ser Ser Glu Tyr Pro Glu Phe Cys Ser Lys Thr Lys Ala Leu Ala
                 155                 160                 165

 Ala Ile Pro Pro Pro Val Pro Pro Ser Ala Thr Glu Pro Leu Asp
                 170                 175                 180

 Leu Gly Cys Ser Ser Cys Gly Thr Pro Leu His Asp Gln Gly Gly
                 185                 190                 195

 Pro Val Glu Ile Leu Pro Phe Leu Tyr Leu Gly Ser Ala Tyr His
                 200                 205                 210

 Ala Ala Arg Arg Asp Met Leu Asp Ala Leu Gly Ile Thr Ala Leu
                 215                 220                 225

 Leu Asn Val Ser Ser Asp Cys Pro Asn His Phe Glu Gly His Tyr
                 230                 235                 240

 Gln Tyr Lys Cys Ile Pro Val Glu Asp Asn His Lys Ala Asp Ile
                 245                 250                 255

 Ser Ser Trp Phe Met Glu Ala Ile Glu Tyr Ile Asp Ala Val Lys
                 260                 265                 270

 Asp Cys Arg Gly Arg Val Leu Val His Cys Gln Ala Gly Ile Ser
                 275                 280                 285

 Arg Ser Ala Thr Ile Cys Leu Ala Tyr Leu Met Met Lys Lys Arg
                 290                 295                 300

 Val Arg Leu Glu Glu Ala Phe Glu Phe Val Lys Gln Arg Arg Ser
                 305                 310                 315

 Ile Ile Ser Pro Asn Phe Ser Phe Met Gly Gln Leu Leu Gln Phe
                 320                 325                 330

 Glu Ser Gln Val Leu Ala Thr Ser Cys Ala Ala Glu Ala Ala Ser
                 335                 340                 345

 Pro Ser Gly Pro Leu Arg Glu Arg Gly Lys Thr Pro Ala Thr Pro
                 350                 355                 360

 Thr Ser Gln Phe Val Phe Ser Phe Pro Val Ser Val Gly Val His
                 365                 370                 375

 Ser Ala Pro Ser Ser Leu Pro Tyr Leu His Ser Pro Ile Thr Thr
                 380                 385                 390

 Ser Pro Ser Cys


<210> 1039
<211> 3404
<212> DNA
<213> Homo sapien

<400> 1039
 gcagttcaga cccccccaca cccatcaaag agccgctcct cccccccgca 50

 ggcgccttcg ccgcctccct cccttccttt cctttccgct cctcttccga 100

 cctgtccacc cgggaggaag ggagctggaa agggggcgga aacctctccc 150

 ctccaaaaag cacaacaaaa ctgttcagtg cggaggagcc gggttcgccc 200

 ctgccggaca gcggggggct ttgttccccg cagttgtttc ctgcccattt 250

 gacctgtcag ctgctgggga aacgctgctg ttgacctttg gttgaactgc 300

 taaggcgatt ttgctgattt ttctttcttt ttccgcgagg gctgtctttt 350

 gctcctccaa atgagcccag tccccctccc ttctccccaa agcgctccaa 400

 gagaaagtgc caggaagggg cttgtcccgg aaggcctggc ggctgagcgg 450

 ggccaggtcc tggttaggcc accagggtgg gcgtccgcgc cattgtttga 500

 gcttgtcggc gctggtggga gagatgaggg caattcctct gggacgcaag 550

 tcccctcgaa tggccggggc tggccgggat gttccccgca cggcgctgcc 600

 ctcgagtccc cccgatggag agcgcgggcg cgccttcctt cgctggcgtc 650

 caaacccggg accagctaga acacagcagg gctgggactg ggttccagcc 700

 ccacgtggag tctggatttg ttttgttgtg ttttgctttc cttcctggaa 750

 gaaatcccga ggggaccgcc ctagagcggc agctccagga cctcggccct 800

 tgggcttccg ggggtgcagc cacttaggcc ccgctcccgg ggagagaggg 850

 attatttttt aagatttatc cccagggcgc gcggcatttc cctgtccctc 900

 gtgaatcccg ttgagagtcc tccctcccca acctcctcca tttccccagc 950

 cagaccgatt cgagagccct ggagattctg ggcgaggcta gtgactgggt 1000

 agtacaggcc tctagcccca ccattgctct ctctgtcttc agttccccag 1050

 gagggcaatg gcatcaaaca gcacagctct gggggatgtc aatattgcat 1100

 accttttcta cctaaaggga aaatgactcg cttttctgct tgcaaatatg 1150

 gtagtttctg cttacaaatg taatacaatg cccatgacag ccaaggactg 1200

 gaagcataag ttgctaggtc ttacaggtga ttttttacaa tgaagcaaac 1250

 tcactatgtt agacaccatt tacattggat gtctccaact aacaaaagta 1300

 actaaagaca gatgtaggtg taaattgaga gtgaaatttg accctttaga 1350

 ccgtcacaac ttccttgggc ttatcctggg tgcttatagg agaggtgggc 1400

 tccacccaca aaaatggact gctcagaaaa atgagggaga gagaaagggt 1450

 ggccactttc ccgagccaag aaattccttg aaaaaaaatc agaacatctg 1500

 aaaccagaga gccgatttcc ttaccgggag gcagttcctg gctaacgaag 1550

 aggaagcacg atgggaagaa aagttcactc caacggaagc cagtttgctg 1600

 aacatagcag atcgcccagg aggactggga gagactgcaa accagttcga 1650

 gcccccagca tggcgttagg tgtcagccag ctggcaggaa ggtccaggtg 1700

 tctgtgttca gagtctcaag gcggctatga gaggttttcc tccgagtacc 1750

 cagaattctg ttctaaaacc aaggccctgg cagccatccc acccccggtt 1800

 ccccccagtg ccacagagcc cttggacctg ggctgcagct cctgtgggac 1850

 cccactacac gaccaggggg gtcctgtgga gatccttccc ttcctctacc 1900

 tcggcagtgc ctaccatgct gcccggagag acatgctgga cgccctgggc 1950

 atcacggctc tgttgaatgt ctcctcggac tgcccaaacc actttgaagg 2000

 acactatcag tacaagtgca tcccagtgga agataaccac aaggccgaca 2050

 tcagctcctg gttcatggaa gccatagagt acatcgatgc cgtgaaggac 2100

 tgccgtgggc gcgtgctggt gcactgccag gcgggcatct cgcggtcggc 2150

 caccatctgc ctggcctacc tgatgatgaa gaaacgggtg aggctggagg 2200

 aggccttcga gttcgttaag cagcgccgca gcatcatctc gcccaacttc 2250

 agcttcatgg ggcagctgct gcagttcgag tcccaggtgc tggccacgtc 2300

 ctgtgctgcg gaggctgcta gcccctcggg acccctgcgg gagcggggca 2350

 agacccccgc cacccccacc tcgcagttcg tcttcagctt tccggtctcc 2400

 gtgggcgtgc actcggcccc cagcagcctg ccctacctgc acagccccat 2450

 caccacctct cccagctgtt agagccgccc tgggggcccc agaaccagag 2500

 ctggctccca gcaagggtag gacgggccgc atgcgggcag aaagttggga 2550

 ctgagcagct gggagcaggc gaccgagctc cttccccatc atttctcctt 2600

 ggccaacgac gaggccagcc agaatggcaa taaggactcc gaatacataa 2650

 taaaagcaaa cagaacactc caacttagag caataacggc tgccgcagca 2700

 gccagggaag accttggttt ggtttatgtg tcagtttcac ttttccgata 2750

 gaaatttctt acctcatttt tttaagcagt aaggcttgaa gtgatgaaac 2800

 ccacagatcc tagcaaatgt gcccaaccag ctttactaaa gggggaggaa 2850

 gggagggcaa agggatgaga agacaagttt cccagaagtg cctggttctg 2900

 tgtacttgtc cctttgttgt cgttgttgta gttaaaggaa tttcattttt 2950

 taaaagaaat cttcgaaggt gtggttttca tttctcagtc accaacagat 3000

 gaataattat gcttaataat aaagtattta ttaagacttt cttcagagta 3050

 tgaaagtaca aaaagtctag ttacagtgga tttagaatat atttatgttg 3100

 atgtcaaaca gctgagcacc gtagcatgca gatgtcaagg cagttaggaa 3150

 gtaaatggtg tcttgtagat atgtgcaagg tagcatgatg agcaacttga 3200

 gtttgttgcc actgagaagc aggcgggttg ggtgggagga ggaagaaagg 3250

 gaagaattag gtttgaattg ctttttaaaa aaaaaagaaa agaaaaagac 3300

 agcatctcac tatgttgcca aggctcatct tgagaagcag gcgggttggg 3350

 tgggaggagg aagaaaggga agaattaggt ttgaattgct tttttaaaaa 3400

 aaaa 3404

<210> 1040
<211> 303
<212> PRT
<213> Homo sapien

<400> 1040
 Met Gly Arg Lys Val His Ser Asn Gly Ser Gln Phe Ala Glu His
   1               5                  10                  15

 Ser Arg Ser Pro Arg Arg Thr Gly Arg Asp Cys Lys Pro Val Arg
                  20                  25                  30

 Ala Pro Ser Met Ala Leu Gly Val Ser Gln Leu Ala Gly Arg Ser
                  35                  40                  45

 Arg Cys Leu Cys Ser Glu Ser Gln Gly Gly Tyr Glu Arg Phe Ser
                  50                  55                  60

 Ser Glu Tyr Pro Glu Phe Cys Ser Lys Thr Lys Ala Leu Ala Ala
                  65                  70                  75

 Ile Pro Pro Pro Val Pro Pro Ser Ala Thr Glu Pro Leu Asp Leu
                  80                  85                  90

 Gly Cys Ser Ser Cys Gly Thr Pro Leu His Asp Gln Gly Gly Pro
                  95                 100                 105

 Val Glu Ile Leu Pro Phe Leu Tyr Leu Gly Ser Ala Tyr His Ala
                 110                 115                 120

 Ala Arg Arg Asp Met Leu Asp Ala Leu Gly Ile Thr Ala Leu Leu
                 125                 130                 135

 Asn Val Ser Ser Asp Cys Pro Asn His Phe Glu Gly His Tyr Gln
                 140                 145                 150

 Tyr Lys Cys Ile Pro Val Glu Asp Asn His Lys Ala Asp Ile Ser
                 155                 160                 165

 Ser Trp Phe Met Glu Ala Ile Glu Tyr Ile Asp Ala Val Lys Asp
                 170                 175                 180

 Cys Arg Gly Arg Val Leu Val His Cys Gln Ala Gly Ile Ser Arg
                 185                 190                 195

 Ser Ala Thr Ile Cys Leu Ala Tyr Leu Met Met Lys Lys Arg Val
                 200                 205                 210

 Arg Leu Glu Glu Ala Phe Glu Phe Val Lys Gln Arg Arg Ser Ile
                 215                 220                 225

 Ile Ser Pro Asn Phe Ser Phe Met Gly Gln Leu Leu Gln Phe Glu
                 230                 235                 240

 Ser Gln Val Leu Ala Thr Ser Cys Ala Ala Glu Ala Ala Ser Pro
                 245                 250                 255

 Ser Gly Pro Leu Arg Glu Arg Gly Lys Thr Pro Ala Thr Pro Thr
                 260                 265                 270

 Ser Gln Phe Val Phe Ser Phe Pro Val Ser Val Gly Val His Ser
                 275                 280                 285

 Ala Pro Ser Ser Leu Pro Tyr Leu His Ser Pro Ile Thr Thr Ser
                 290                 295                 300

 Pro Ser Cys


<210> 1041
<211> 1982
<212> DNA
<213> Homo sapien

<400> 1041
 gcggacgcgt gggctggaaa caacccaatt gtctatcaac agtgactgga 50

 aggacaaatt gtgctatgtc cacacattag aataccagtt ggcagtcaaa 100

 aaggaagagc tgatctgtgc agcaatttga gtctcagtaa tttcatgtga 150

 ataaccctat accttccaat ttgaaatcag aagcaaaaaa ggctgccaaa 200

 atattaagag aattcacaga aataacttcc agaaatggac ctgataagat 250

 cattcctgct cacgtaattg cgaaggctaa aggccttgca attctgtctg 300

 tgatcaaagc cgggttcctg gtgactgcca gaggaggcag cgggattgta 350

 gtggcgcgcc ttccagatgg aaaatggtct gcaccctcag ccattgggat 400

 agctggcctt ggtggaggat ttgaaatagg aattgagaca catttacagc 450

 tacatattcc ctctgagcat tgccctggct gccttccata agtgtggagt 500

 gccactccag ctttcttagg ttgccatctg catgacacat ctttctccat 550

 ccttttactg tcaatctaat ggtatcagac ttggtgataa ttctgaatta 600

 tgaccgtgct gtagaagctt ttgcaaaagg cggaaatctg accctcggag 650

 ggaacttgac tgtggcggtt gggcccttgg gaaggaactt ggaaggaaac 700

 gtggccctga gaagctccgc tgccgtcttc acgtactgca agtcaagggg 750

 actctttgca ggcgtgtctt tagaagggag ctgtttgatt gaaaggaaag 800

 aaactaatag aaaattttat tgtcaagata tccgagctta tgacatttta 850

 tttggagata caccgcggcc tgctcaagcc gaagatcttt atgaaattct 900

 tgattccttt actgaaaagt atgaaaatga aggacaacga atcaatgcaa 950

 gaaaagcagc aagggagcag aggaagtctt ctgctaaaga attacctcca 1000

 aagccattgt caagaccaca gcagtcatct gcaccagtcc agctgaactc 1050

 tggctctcaa agcaacagaa atgaatataa gctctatcct ggactttcca 1100

 gctatcatga gagagttggc aatttgaatc aacccataga agtgacagcg 1150

 ctgtattcat ttgaaggaca gcagcctggg gatttgaatt ttcaagctgg 1200

 agacagaatc acagttatat caaaaacaga ttcacatttt gattggtggg 1250

 aaggaaaact tcgaggtcaa actggcattt ttccagccaa ctacgtaacc 1300

 atgaattaaa gcgtatacta ttttcttctt tgagaattac aaaaaaatta 1350

 tttctacact gacaggattt actagttaag caatgtttaa tataaatttt 1400

 aaaaaacttc tgttctacaa aatttccatt ccgtatgtaa aagattttgt 1450

 ttttctatat aaaaagagct gactgacata tctttaaata ctttgtacta 1500

 actttatcac acttactgtg tcatagaata tcatacagtt tatacgctca 1550

 tagttctctt gtgaacactt caaacatcgc taagcatttg atctggccat 1600

 gtatatggta gctgtgtttt aatttgagaa tcttgagggt agagccacaa 1650

 atttcaattc ttacatttcc atttgcaaag tgactagaga aaaagaaatc 1700

 agcttaaatg aggtattaag taatgtttag agttgtaggt attaactaga 1750

 atataaatcc ttagaaattg tctttatacc ttcaaaaatt atactatgca 1800

 tttatcatag aaatgtgatt acaaagaagt ctgactacca tgtctttaaa 1850

 catatggcat ctctcaactt ttcttcctta tggggctaca tttgttcatt 1900

 tccagcagta gcataaactt acggtgacat ggtagacttg tctctaaata 1950

 aaatttttaa atgttaaaaa aaaaaaaaaa aa 1982

<210> 1042
<211> 246
<212> PRT
<213> Homo sapien

<400> 1042
 Met Val Ser Asp Leu Val Ile Ile Leu Asn Tyr Asp Arg Ala Val
   1               5                  10                  15

 Glu Ala Phe Ala Lys Gly Gly Asn Leu Thr Leu Gly Gly Asn Leu
                  20                  25                  30

 Thr Val Ala Val Gly Pro Leu Gly Arg Asn Leu Glu Gly Asn Val
                  35                  40                  45

 Ala Leu Arg Ser Ser Ala Ala Val Phe Thr Tyr Cys Lys Ser Arg
                  50                  55                  60

 Gly Leu Phe Ala Gly Val Ser Leu Glu Gly Ser Cys Leu Ile Glu
                  65                  70                  75

 Arg Lys Glu Thr Asn Arg Lys Phe Tyr Cys Gln Asp Ile Arg Ala
                  80                  85                  90

 Tyr Asp Ile Leu Phe Gly Asp Thr Pro Arg Pro Ala Gln Ala Glu
                  95                 100                 105

 Asp Leu Tyr Glu Ile Leu Asp Ser Phe Thr Glu Lys Tyr Glu Asn
                 110                 115                 120

 Glu Gly Gln Arg Ile Asn Ala Arg Lys Ala Ala Arg Glu Gln Arg
                 125                 130                 135

 Lys Ser Ser Ala Lys Glu Leu Pro Pro Lys Pro Leu Ser Arg Pro
                 140                 145                 150

 Gln Gln Ser Ser Ala Pro Val Gln Leu Asn Ser Gly Ser Gln Ser
                 155                 160                 165

 Asn Arg Asn Glu Tyr Lys Leu Tyr Pro Gly Leu Ser Ser Tyr His
                 170                 175                 180

 Glu Arg Val Gly Asn Leu Asn Gln Pro Ile Glu Val Thr Ala Leu
                 185                 190                 195

 Tyr Ser Phe Glu Gly Gln Gln Pro Gly Asp Leu Asn Phe Gln Ala
                 200                 205                 210

 Gly Asp Arg Ile Thr Val Ile Ser Lys Thr Asp Ser His Phe Asp
                 215                 220                 225

 Trp Trp Glu Gly Lys Leu Arg Gly Gln Thr Gly Ile Phe Pro Ala
                 230                 235                 240

 Asn Tyr Val Thr Met Asn
                 245

<210> 1043
<211> 1658
<212> DNA
<213> Homo sapien

<400> 1043
 ggcacgagct cggctcctgg aaagatggag gcagcggaga cagaggcgga 50

 agctgcagcc ctagaggtcc tggctgaggt ggcaggcatc ttggaacctg 100

 taggcctgca ggaggaggca gaactgccag ccaagatcct ggttgagttt 150

 gtggtggact ctcagaagaa agacaagctg ctctgcagcc agcttcaggt 200

 agcggatttc ctgcagaaca tcctggctca ggaggacact gctaagggtc 250

 tcgacccctt ggcttctgaa gacacgagcc gacagaaggc aattgcagct 300

 aaggaacaat ggaaagagct gaaggccacc tacagggagc acgtagaggc 350

 catcaaaatt ggcctcacca aggccctgac tcagatggag gaagcccaga 400

 ggaaacggac acaactccgg gaagcctttg agcagctcca ggccaagaaa 450

 caaatggcca tggagaaacg cagagcagtc cagaaccagt ggcagctaca 500

 acaggagaag catctgcagc atctggcgga ggtttctgca gaggtgaggg 550

 agcgtaagac agggactcag caggagcttg acagggtgtt tcagaaactt 600

 ggaaacctga agcagcaggc agaacaggag cgggacaagc tgcagaggta 650

 tcagaccttc ctccagcttc tgtataccct gcagggtaag ctgttgttcc 700

 ctgaggctga ggctgaggca gagaatcttc cagatgataa accccagcag 750

 ccgactcgac cccaggagca gagtacagga gacaccatgg ggagagaccc 800

 tggtgtgtcc ttcaaggctg ttggtctaca acctgctgga gatgtaaatt 850

 tgccatgact tcctggagga cagcagcatg gagaaagatc ctagaaaagg 900

 cctctgactt ccctcacctc ccaaccatca ttacaggaaa gactgtgaac 950

 tcctgagttc agcttgattt ctgactacat cccagcaagc tctggcatct 1000

 gtggattaaa atccctggat ctctctcagt tgtgtatttg ttcatcttca 1050

 tatgctggca ggaacaacta ttaatacaga tactcagaag ccaataacat 1100

 gacaggagct gggactggtt tgaacacagg gtgtgcagat ggggaggggg 1150

 tactggcctt gggcctccta tgatgcagac atggtgaatt taattcaagg 1200

 aggaggagaa tgttttaggc aggtggttat atgtgggaag ataattttat 1250

 tcatggatcc aaatgtttgt tgagtccttt ctttgtgcta aggttcttgc 1300

 ggtgaaccag aattataaca gtgagctcat ctgactgttt taggatgtac 1350

 agcctagtgt taacattctt ggtatctttt tgtgccttat ctaaaacatt 1400

 tctcgatcac tggtttcaga tgttcattta ttatattctt ttcaaagatt 1450

 cagagattgg cttttgtcat ccactattgt atgttttgtt tcattgacct 1500

 ctagtgatac cttgatcttt cccactttct gttttcggat tggagaagat 1550

 gtaccttttt tgtcaactct tacttttatc agatgatcaa ctcacgtatt 1600

 tggatcttta tttgttttct caaataaata tttaaggtta aaaaaaaaaa 1650

 aaaaaaaa 1658

<210> 1044
<211> 277
<212> PRT
<213> Homo sapien

<400> 1044
 Met Glu Ala Ala Glu Thr Glu Ala Glu Ala Ala Ala Leu Glu Val
   1               5                  10                  15

 Leu Ala Glu Val Ala Gly Ile Leu Glu Pro Val Gly Leu Gln Glu
                  20                  25                  30

 Glu Ala Glu Leu Pro Ala Lys Ile Leu Val Glu Phe Val Val Asp
                  35                  40                  45

 Ser Gln Lys Lys Asp Lys Leu Leu Cys Ser Gln Leu Gln Val Ala
                  50                  55                  60

 Asp Phe Leu Gln Asn Ile Leu Ala Gln Glu Asp Thr Ala Lys Gly
                  65                  70                  75

 Leu Asp Pro Leu Ala Ser Glu Asp Thr Ser Arg Gln Lys Ala Ile
                  80                  85                  90

 Ala Ala Lys Glu Gln Trp Lys Glu Leu Lys Ala Thr Tyr Arg Glu
                  95                 100                 105

 His Val Glu Ala Ile Lys Ile Gly Leu Thr Lys Ala Leu Thr Gln
                 110                 115                 120

 Met Glu Glu Ala Gln Arg Lys Arg Thr Gln Leu Arg Glu Ala Phe
                 125                 130                 135

 Glu Gln Leu Gln Ala Lys Lys Gln Met Ala Met Glu Lys Arg Arg
                 140                 145                 150

 Ala Val Gln Asn Gln Trp Gln Leu Gln Gln Glu Lys His Leu Gln
                 155                 160                 165

 His Leu Ala Glu Val Ser Ala Glu Val Arg Glu Arg Lys Thr Gly
                 170                 175                 180

 Thr Gln Gln Glu Leu Asp Arg Val Phe Gln Lys Leu Gly Asn Leu
                 185                 190                 195

 Lys Gln Gln Ala Glu Gln Glu Arg Asp Lys Leu Gln Arg Tyr Gln
                 200                 205                 210

 Thr Phe Leu Gln Leu Leu Tyr Thr Leu Gln Gly Lys Leu Leu Phe
                 215                 220                 225

 Pro Glu Ala Glu Ala Glu Ala Glu Asn Leu Pro Asp Asp Lys Pro
                 230                 235                 240

 Gln Gln Pro Thr Arg Pro Gln Glu Gln Ser Thr Gly Asp Thr Met
                 245                 250                 255

 Gly Arg Asp Pro Gly Val Ser Phe Lys Ala Val Gly Leu Gln Pro
                 260                 265                 270

 Ala Gly Asp Val Asn Leu Pro
                 275

<210> 1045
<211> 2112
<212> DNA
<213> Homo sapien

<400> 1045
 cggctttcaa agccaatttg aataaacaac tcttccctct caaatgggca 50

 agagtaactc ttcagcacca tggagaggtc cgggcagcgt gttacaacgt 100

 gggactgtga ccagggcaag cactctgaca gtgattaccg agaggatggg 150

 atggatctag gcagtgacgc cggcagcagc agcagcagca gccgcgccag 200

 ttcacagtcc aactccacca aagtgacccc ttgctccgag tgcaaatctt 250

 catcgtcgcc ggggggcagc ctggacttgg tgtctgccct ggaggactat 300

 gaggagccct tcccggtcta ccagaagaag gtgattgatg agtgggcgcc 350

 ggaggaggac ggggaggagg aggaagagga ggacgagcgc gaccagcgag 400

 ggtaccggga tgaccgctct ccggcccggg aaccggggga cgtaagcgcc 450

 aggacccgca gcggcggcgg cgggggcagg agcgccacca ccgccatgcc 500

 gcccccggtg cccaacggca acctccacca gcacgacccc caggacctca 550

 ggcacaatgg caacgtggtg gtggctggcc ggccgagctg ttcccggggc 600

 ccccgccggg cgatccaaaa gccccagccg gctgggggcc ggcgcagtgg 650

 ccgcggcccg gcggctgggg ggctctgcct tcagccccca gacggcggga 700

 cgtgcgtccc cgaagagccc ccggtgccac ctatggattg ggaggcgctg 750

 gagaagcatc tggccgggct gcagttccgg gagcaggagg tacggaacca 800

 gggccaggcg aggaccaact ccacctccgc acagaaaaat gagagagagt 850

 ctatcagaca gaagttggca cttggaagct tctttgatga tggcccagga 900

 atttatacca gctgtagcaa aagtgggaag ccaagccttt cctcccgact 950

 gcagagtggg atgaacttgc agatatgctt tgtcaacgac agtggcagtg 1000

 ataaggacag tgatgctgat gacagtaaga ctgaaaccag cttggacacc 1050

 cccttgtctc ccatgagcaa acagagttct tcctattctg atagagacac 1100

 tactgaagag gagtctgaat ccttggatga catggacttc cttacaaggc 1150

 aaaagaaatt gcaagctgaa gccaaaatgg cccttgccat ggccaaacca 1200

 atggccaaaa tgcaagtaga agtggagaaa cagaacagga aaaagtctcc 1250

 cgtcgctgat cttctgccac acatgcctca tataagtgaa tgcttgatga 1300

 aaagaagttt aaaacccacc gacctgagag acatgactat tgggcagcta 1350

 caagtgatag tcaatgatct ccattcccag atagaaagct tgaatgaaga 1400

 gttggtccag ctgcttctca tccgagatga gctgcacaca gagcaggatg 1450

 ccatgctggt ggacattgaa gacttgacca gacatgctga aagtcagcag 1500

 aagcacatgg cagagaaaat gcctgcaaag tgaaaagaag ccattcaacc 1550

 agagaacaag ctagaattta ttttgcttct gtggttgtaa aaatgctgtt 1600

 gctaaaggtg gcgcagaaac aaatatcagt gttagtcatt gataatgtct 1650

 gaagcttaat gtccagtgat tggcctttgc ttcttaattt attttaattt 1700

 tttacttgtg ccacttaata tcaggcattt taataaaata ttgttacaaa 1750

 aaatgtacag tactgacacc accacaaatc atggttaata aaagagagta 1800

 gttttaactt tatttttatt tgtttagaga ttttaagttg gaacagtatt 1850

 ttcccattga ctacttttca ttcttcactg tagttttaaa gaagaactgt 1900

 aaatgacggt gctatacaag tcaaaaaata catgcctgcc tcgtagtgaa 1950

 gttgtagctc tccgtaatat gtatatttta ctcagttttc aacattttgt 2000

 gaatgttgac tacctgaagt tcctttttag atgtgctatt aacattctgt 2050

 tggattcaga gggttccttg aaagttttat gtataaatat gtaaaataaa 2100

 aattaaaacc cg 2112

<210> 1046
<211> 487
<212> PRT
<213> Homo sapien

<400> 1046
 Met Glu Arg Ser Gly Gln Arg Val Thr Thr Trp Asp Cys Asp Gln
   1               5                  10                  15

 Gly Lys His Ser Asp Ser Asp Tyr Arg Glu Asp Gly Met Asp Leu
                  20                  25                  30

 Gly Ser Asp Ala Gly Ser Ser Ser Ser Ser Ser Arg Ala Ser Ser
                  35                  40                  45

 Gln Ser Asn Ser Thr Lys Val Thr Pro Cys Ser Glu Cys Lys Ser
                  50                  55                  60

 Ser Ser Ser Pro Gly Gly Ser Leu Asp Leu Val Ser Ala Leu Glu
                  65                  70                  75

 Asp Tyr Glu Glu Pro Phe Pro Val Tyr Gln Lys Lys Val Ile Asp
                  80                  85                  90

 Glu Trp Ala Pro Glu Glu Asp Gly Glu Glu Glu Glu Glu Glu Asp
                  95                 100                 105

 Glu Arg Asp Gln Arg Gly Tyr Arg Asp Asp Arg Ser Pro Ala Arg
                 110                 115                 120

 Glu Pro Gly Asp Val Ser Ala Arg Thr Arg Ser Gly Gly Gly Gly
                 125                 130                 135

 Gly Arg Ser Ala Thr Thr Ala Met Pro Pro Pro Val Pro Asn Gly
                 140                 145                 150

 Asn Leu His Gln His Asp Pro Gln Asp Leu Arg His Asn Gly Asn
                 155                 160                 165

 Val Val Val Ala Gly Arg Pro Ser Cys Ser Arg Gly Pro Arg Arg
                 170                 175                 180

 Ala Ile Gln Lys Pro Gln Pro Ala Gly Gly Arg Arg Ser Gly Arg
                 185                 190                 195

 Gly Pro Ala Ala Gly Gly Leu Cys Leu Gln Pro Pro Asp Gly Gly
                 200                 205                 210

 Thr Cys Val Pro Glu Glu Pro Pro Val Pro Pro Met Asp Trp Glu
                 215                 220                 225

 Ala Leu Glu Lys His Leu Ala Gly Leu Gln Phe Arg Glu Gln Glu
                 230                 235                 240

 Val Arg Asn Gln Gly Gln Ala Arg Thr Asn Ser Thr Ser Ala Gln
                 245                 250                 255

 Lys Asn Glu Arg Glu Ser Ile Arg Gln Lys Leu Ala Leu Gly Ser
                 260                 265                 270

 Phe Phe Asp Asp Gly Pro Gly Ile Tyr Thr Ser Cys Ser Lys Ser
                 275                 280                 285

 Gly Lys Pro Ser Leu Ser Ser Arg Leu Gln Ser Gly Met Asn Leu
                 290                 295                 300

 Gln Ile Cys Phe Val Asn Asp Ser Gly Ser Asp Lys Asp Ser Asp
                 305                 310                 315

 Ala Asp Asp Ser Lys Thr Glu Thr Ser Leu Asp Thr Pro Leu Ser
                 320                 325                 330

 Pro Met Ser Lys Gln Ser Ser Ser Tyr Ser Asp Arg Asp Thr Thr
                 335                 340                 345

 Glu Glu Glu Ser Glu Ser Leu Asp Asp Met Asp Phe Leu Thr Arg
                 350                 355                 360

 Gln Lys Lys Leu Gln Ala Glu Ala Lys Met Ala Leu Ala Met Ala
                 365                 370                 375

 Lys Pro Met Ala Lys Met Gln Val Glu Val Glu Lys Gln Asn Arg
                 380                 385                 390

 Lys Lys Ser Pro Val Ala Asp Leu Leu Pro His Met Pro His Ile
                 395                 400                 405

 Ser Glu Cys Leu Met Lys Arg Ser Leu Lys Pro Thr Asp Leu Arg
                 410                 415                 420

 Asp Met Thr Ile Gly Gln Leu Gln Val Ile Val Asn Asp Leu His
                 425                 430                 435

 Ser Gln Ile Glu Ser Leu Asn Glu Glu Leu Val Gln Leu Leu Leu
                 440                 445                 450

 Ile Arg Asp Glu Leu His Thr Glu Gln Asp Ala Met Leu Val Asp
                 455                 460                 465

 Ile Glu Asp Leu Thr Arg His Ala Glu Ser Gln Gln Lys His Met
                 470                 475                 480

 Ala Glu Lys Met Pro Ala Lys
                 485

<210> 1047
<211> 2735
<212> DNA
<213> Homo sapien

<400> 1047
 gggggcctgg agcgcggcag caagcgtggg aacgcgggcg gcgagacggc 50

 ggcaggacgg cggcaggatg tgtgaccgga atggtggtcg gcggcttcga 100

 cagtggctga tcgagcagat tgacagtagc atgtatccag gactgatttg 150

 ggagaatgag gagaagagca tgttccggat cccttggaaa cacgctggca 200

 agcaagatta taatcaggaa gtggatgcct ccatttttaa ggcctgggca 250

 gtttttaaag ggaagtttaa agaaggggac aaagctgaac cagccacttg 300

 gaagacgagg ttacgctgtg ctttgaataa gagcccagat tttgaggaag 350

 tgacggaccg gtcccaactg gacatttccg agccatacaa agtttaccga 400

 attgttcctg aggaagagca aaaatgcaaa ctaggcgtgg caactgctgg 450

 ctgcgtgaat gaagttacag agatggagtg cggtcgctct gaaatcgacg 500

 agctgatcaa ggagccttct gtggacgatt acatggggat gatcaaaagg 550

 agcccttccc cgccggaggc ctgtcggagt cagctccttc cagactggtg 600

 ggcgcagcag cccagcacag gcgtgccgct ggtgacgggg tacaccacct 650

 acgacgcgca ccattcagca ttctcccaga tggtgatcag cttctactat 700

 gggggcaagc tggtgggcca ggccaccacc acctgccccg agggctgccg 750

 cctgtccctg agccagcctg ggctgcccgg caccaagctg tatgggcccg 800

 agggcctgga gctggtgcgc ttcccgccgg ccgacgccat ccccagcgag 850

 cgacagaggc aggtgacgcg gaagctgttc gggcacctgg agcgcggggt 900

 gctgctgcac agcagccggc agggcgtgtt cgtcaagcgg ctgtgccagg 950

 gccgcgtgtt ctgcagcggc aacgccgtgg tgtgcaaagg caggcccaac 1000

 aagctggagc gtgatgaggt ggtccaggtc ttcgacacca gccagttctt 1050

 ccgagagctg cagcagttct ataacagcca gggccggctt cctgacggca 1100

 gggtggtgct gtgctttggg gaagagtttc cggatatggc ccccttgcgc 1150

 tccaaactca ttctcgtgca gattgagcag ctgtatgtcc ggcaactggc 1200

 agaagaggct gggaagagct gtggagccgg ctctgtgatg caggcccccg 1250

 aggagccgcc gccagaccag gtcttccgga tgtttccaga tatttgtgcc 1300

 tcacaccaga gatcattttt cagagaaaac caacagatca ccgtctaagt 1350

 gcgtcgcttg ggcgccccac cccgtctgcg tcctgcatcc atctccctgt 1400

 tacagtggcc cgcatcatga ttaaagaatg tggatccctc tgtctggggt 1450

 gggatgcctt actttgcact taatttaata agggcattct cggaggagta 1500

 gacgtttaat acgaagtggc ggcatagccc tgccgagatg tcggtgatgg 1550

 cctggatgct gtaaccacaa cctgtggcta aaaattttat tttctatcct 1600

 ttacccgtca ttatcattag ttgctatgat tctttctgca ttttcggtta 1650

 actatcattt ccaaagactt gtcattcagt aatattagca gatagctgct 1700

 tcgataaagg aatttggagt ttaaaaatca acttgtgaaa acaaggttgt 1750

 ttttgtcttt atcgtttgtt agagttatag atttatgatt tcataggctt 1800

 gattctatgt gaaatatctt tttactttta tgcattttaa taagatttaa 1850

 aaatatttag attaaagccc cctttaatga gtacaagaaa aactcttggc 1900

 ttgttagaag aaagtatatt ctttctagaa tttggtgcag gaatatgtgt 1950

 tcatatccag gcaaacgggt gtgtttttat cttcagacaa tgaaaccttc 2000

 tcctctgggg ctttgttgcc aggaagatta gaactaaatt tatttttttc 2050

 atttctgtca tgaaatcatt ccagatacct cttttcttct ttccaaatgg 2100

 ttttcacatg tgtttgaaat atttgtactt cgaattgtcg gattttccat 2150

 gtcctccttt ctcctttgtg cccagcctga gtcagcacca atcccgcatt 2200

 cagaacctcc cagtgaaagg gcagccttca ttttgagaag gtggaaggtg 2250

 ttagggtttg ggagacagct catccaatct cccaagtctc atggtggatt 2300

 tgtgactgtg agagtttccg gtttaaaatc tgaaaagcca gatatgcctg 2350

 tttccttttc ccagcaccat gcctgtggag gggacagtca gacccagagg 2400

 tcctttacgt gtggatggag ttcacaggcg aatagaggag aggaccaggg 2450

 gacgtggctt gtcccttttg tccaacaaag cattatattt ttaagaatgg 2500

 cagtcctgtt tgctgaagtg ttcataagat aacaataggc ttgaatctcc 2550

 aattcaaatg aatgtcaaag cacatatctt taatatgctg aatgaatatt 2600

 tatttttgta tccattaaaa cagtatattg atctctttta ttctttatta 2650

 aaataaaatg ctccaaaaaa aatctatgtc gggtgcggag aaagaggtaa 2700

 tgaaatggca ggaattcgat atcagcttat cgata 2735

<210> 1048
<211> 448
<212> PRT
<213> Homo sapien

<400> 1048
 Gly Ala Trp Ser Ala Ala Ala Ser Val Gly Thr Arg Ala Ala Arg
   1               5                  10                  15

 Arg Arg Gln Asp Gly Gly Arg Met Cys Asp Arg Asn Gly Gly Arg
                  20                  25                  30

 Arg Leu Arg Gln Trp Leu Ile Glu Gln Ile Asp Ser Ser Met Tyr
                  35                  40                  45

 Pro Gly Leu Ile Trp Glu Asn Glu Glu Lys Ser Met Phe Arg Ile
                  50                  55                  60

 Pro Trp Lys His Ala Gly Lys Gln Asp Tyr Asn Gln Glu Val Asp
                  65                  70                  75

 Ala Ser Ile Phe Lys Ala Trp Ala Val Phe Lys Gly Lys Phe Lys
                  80                  85                  90

 Glu Gly Asp Lys Ala Glu Pro Ala Thr Trp Lys Thr Arg Leu Arg
                  95                 100                 105

 Cys Ala Leu Asn Lys Ser Pro Asp Phe Glu Glu Val Thr Asp Arg
                 110                 115                 120

 Ser Gln Leu Asp Ile Ser Glu Pro Tyr Lys Val Tyr Arg Ile Val
                 125                 130                 135

 Pro Glu Glu Glu Gln Lys Cys Lys Leu Gly Val Ala Thr Ala Gly
                 140                 145                 150

 Cys Val Asn Glu Val Thr Glu Met Glu Cys Gly Arg Ser Glu Ile
                 155                 160                 165

 Asp Glu Leu Ile Lys Glu Pro Ser Val Asp Asp Tyr Met Gly Met
                 170                 175                 180

 Ile Lys Arg Ser Pro Ser Pro Pro Glu Ala Cys Arg Ser Gln Leu
                 185                 190                 195

 Leu Pro Asp Trp Trp Ala Gln Gln Pro Ser Thr Gly Val Pro Leu
                 200                 205                 210

 Val Thr Gly Tyr Thr Thr Tyr Asp Ala His His Ser Ala Phe Ser
                 215                 220                 225

 Gln Met Val Ile Ser Phe Tyr Tyr Gly Gly Lys Leu Val Gly Gln
                 230                 235                 240

 Ala Thr Thr Thr Cys Pro Glu Gly Cys Arg Leu Ser Leu Ser Gln
                 245                 250                 255

 Pro Gly Leu Pro Gly Thr Lys Leu Tyr Gly Pro Glu Gly Leu Glu
                 260                 265                 270

 Leu Val Arg Phe Pro Pro Ala Asp Ala Ile Pro Ser Glu Arg Gln
                 275                 280                 285

 Arg Gln Val Thr Arg Lys Leu Phe Gly His Leu Glu Arg Gly Val
                 290                 295                 300

 Leu Leu His Ser Ser Arg Gln Gly Val Phe Val Lys Arg Leu Cys
                 305                 310                 315

 Gln Gly Arg Val Phe Cys Ser Gly Asn Ala Val Val Cys Lys Gly
                 320                 325                 330

 Arg Pro Asn Lys Leu Glu Arg Asp Glu Val Val Gln Val Phe Asp
                 335                 340                 345

 Thr Ser Gln Phe Phe Arg Glu Leu Gln Gln Phe Tyr Asn Ser Gln
                 350                 355                 360

 Gly Arg Leu Pro Asp Gly Arg Val Val Leu Cys Phe Gly Glu Glu
                 365                 370                 375

 Phe Pro Asp Met Ala Pro Leu Arg Ser Lys Leu Ile Leu Val Gln
                 380                 385                 390

 Ile Glu Gln Leu Tyr Val Arg Gln Leu Ala Glu Glu Ala Gly Lys
                 395                 400                 405

 Ser Cys Gly Ala Gly Ser Val Met Gln Ala Pro Glu Glu Pro Pro
                 410                 415                 420

 Pro Asp Gln Val Phe Arg Met Phe Pro Asp Ile Cys Ala Ser His
                 425                 430                 435

 Gln Arg Ser Phe Phe Arg Glu Asn Gln Gln Ile Thr Val
                 440                 445

<210> 1049
<211> 6034
<212> DNA
<213> Homo sapien

<400> 1049
 ccacgcgtcc ggagctggag gaggcggcgg gcgcgagacc cggaatgcgc 50

 agggcccccg cctcgccccc cccagcccgg gccgcggccc ccgccttccc 100

 cgcagtcgtc ccgcactcgg tgcccgcccc ccgaggccgg cggctgctcc 150

 cactcggggc cgttgctgct tgtgccgtga gcgccgccca gccattgtcc 200

 ccgtcgctcc gtcagccgcg ccggaccgcg caccaggagg cgagagcgcg 250

 catggggagc ctctgttgat gccgccgccg cgccgccctc cgaggctgcg 300

 tcccgggaag cccggctccc cgagcgctcc ggcctggccc ggtgccccgg 350

 acctgagtgc gtccccatgg aggcgcccgg gctggcccag gcggccgcgg 400

 cggagagcga ctcccgcaag gtggcggagg agacccccga cggggcgccc 450

 gcgctctgcc ccagccctga ggcgctgtcg ccggagccgc ctgtgtacag 500

 cctgcaggac tttgacacgc tggccaccgt gggcactggg acgttcgggc 550

 gggtgcacct ggtgaaggag aagacagcca agcatttctt cgccctcaag 600

 gtgatgagca ttcctgacgt catccgccta aagcaggagc aacacgtaca 650

 caatgagaag tctgtcctga aggaagtcag ccacccgttc ctcatcaggc 700

 tgttctggac gtggcatgac gagcgcttcc tctacatgct catggagtac 750

 gtgccgggcg gcgagctctt cagctacctg cgcaaccggg ggcgcttctc 800

 cagcaccacg gggctcttct actctgcaga gatcatctgt gccatcgagt 850

 acctgcactc caaagagatc gtctacaggg acttgaagcc agagaacatc 900

 ctgctggata gggatggcca cattaagctc acggactttg ggttcgccaa 950

 gaagctggta gacaggactt ggaccctctg tggaacaccc gagtacctag 1000

 cccccgaagt cattcagagc aagggccacg gaagggccgt ggactggtgg 1050

 gccctcggca tcctgatatt cgagatgctt tcggggtttc ctccgttttt 1100

 tgatgacaac ccgtttggca tttatcagaa aattcttgca ggcaaaatag 1150

 atttccccag acatttggat ttccatgtaa aagacctcat taagaaactg 1200

 ctcgtggttg acagaacaag gcgattagga aacatgaaga acggggcgaa 1250

 tgatgtgaag catcatcggt ggttccgctc cgtggactgg gaagctgttc 1300

 cgcagagaaa actgaagcct cccatcgtgc ccaagatagc tggtgacggc 1350

 gacacttcca acttcgaaac ttaccctgag aatgactggg acacagccgc 1400

 gcccgtgccg cagaaggatt tagaaatctt caagaatttc tgaggacagg 1450

 agctcacatc tggaagaaac aggaagattg gaatctgcct ggaacaaaga 1500

 actgcaccta agcagaccag aagcaaaatg tcttcttcac ggcataagga 1550

 catctccact tttctctgta cctgtgtgta tagaaataga ttagagcaca 1600

 gttgaaattc atggaactgg cattatttaa gcaactggaa ttccacactg 1650

 taggaaggtt ttgaaaattg tttggttgta gattttatct tatcctttag 1700

 tgttgtgttc ctactgtgat gtcttggttt ttgtcataga cttaagttta 1750

 taagtttgaa ctggacttgt tcgattataa ccacaaattg tgtgtgtgtg 1800

 tgtgtgtgtg tgtgtgtgtg tgtgtatgcc tgtgtgtata tatagaagtc 1850

 attatggcag atgcacagaa attgtgcagt gatgtaaatg ttcatacttt 1900

 acagagccta taatttttat ttttcaattt gttttttcaa aaatctcttc 1950

 tcggggacaa catctgaagg gtatgttgca tgcattaaaa aaaatcatct 2000

 cacatgcatt ttatagtttt ggggaagaaa atatcatggg gaggtctacc 2050

 ttcagtatct ttagttcttc ttaccgggta acttgagact ttaaaagaag 2100

 aaacaaagag gggaagatat gggagcgaat ttattccaag aatctacaat 2150

 gacattgaag ttgttggagg aatgtactgt atttaaaaaa accttctgtg 2200

 acacattcaa aaatttcatc tgagctggat gcagtggctt gttcctatag 2250

 tcccagcact ttgggaggct gaggtgggtg gattgcttga gcccaggagt 2300

 tggagaccag tctgggaaac gtggtgagac ctcatctcta caaaatacaa 2350

 aaaaattagc cgggcatggt ggcacgtgag ttaggtctca gctactcagg 2400

 aggctgagat gagaggatca cttgagcctg gggaggtcca ggccgcagtg 2450

 atccgagatc acaccactgc attccagcct gggtgacaga gtgagaccct 2500

 gtccaaaaaa aaaaaaaaaa aaaagaaggc aatggctttg tgcttttgaa 2550

 gatggattga agagaacgtc caccttaagg ctttaaaaga cagtgaagct 2600

 gggtgcggtg gtgcactcct gtaaccctgg gactttggga agctgaggca 2650

 ggaagattga gcctaggagt tcgagactga cctgggcagc atagcgagac 2700

 cccatctcta tataaaaaaa aagatgttaa aacagtgaaa ttacagaaac 2750

 agaacatagc cacccttttt catcagtgac cttttcttca cgtggaggtc 2800

 aactcagtag gtgagaataa ttagtaggtt cagcagaata aactctttac 2850

 aattaataac tcagtggaaa atgatgttca gatggtgaaa tgtggaaatg 2900

 ttttagacaa ctctattttc agcctgtgct tctcactcac catcctgttg 2950

 ggattaacag ttgagggcca tcgctgccta aacatttagc gtgcggtttc 3000

 ccatcagttt taccgtgaat gtgaaaaggt gaaactggtg ctgacttcgg 3050

 cagcaggtat actaaaattg gaatgacaca gaggagatta gcatggcccc 3100

 ctgcgcgagg aagatctgca gattcatgca gcattccata tttttttaag 3150

 aaaaggttac actgtgcacc gacatgtgga gctagaagga aaagctttta 3200

 agtctcatgt ttgctgacta taaaaataaa tcatagtaat aatattgaac 3250

 attctacttt aaaaattatt aataaaacca taaatgaaac acttgagcac 3300

 actttaaaaa gtacataaat ccatgagtcc atatgcctat ttttaggttg 3350

 tctgttttat tatccaggat ttcatactca gatgagaatt agcatcagga 3400

 aagcctgaaa tgccttaatt gtgaactgat atgcaggaaa atgaaatatg 3450

 caagcacatt ggtgaccttg ttctttacag acgtcgtgat cagcctccag 3500

 ccatacagaa caaatgagaa attagaagcg attccaagaa cgtgtgatgg 3550

 tgtgaaccca ctttggacca tcacacacat ttcagcattt gaagtgacac 3600

 aagctacctg gtaactgccc atggcggggt catagtttaa atggcccaat 3650

 gtcatgtaga ggttaattta atcaaaatga gctataaaca tggagcaatc 3700

 actgtataat tttaaaatag tttacctggc caggcatggt cgtcacgcct 3750

 gtaatcccag cactttggga ggccgaggca ggtggatcac ctgaggtcag 3800

 gagttcgaga ccagcctggc caacatggca aaacccccgt ctctactaaa 3850

 atacaaaaat taggtgtggt ggcgggcacc tgtaatcctg gctactcggg 3900

 aggctgaggc aggagaatcg cttgaacccg ggaggcagag gctgcagtga 3950

 gccgagatcg tgccactgca ctccagcctg ggccacagag caagactccg 4000

 tctcaaaaca taaaaataaa aaaaatacaa atagctgacc cgggtgggca 4050

 ttccaaaatg tccgcatgga cgatcacgaa acaatcacgg tgcgaaatgt 4100

 ccgcatggat gatcacgaaa caatcacggt gcggaatgtc cgtatggatg 4150

 atcatgacaa acaatcactg cgcaaaatgt ggaggaaaat tcattaccat 4200

 aatcacaaca tttgtatcag aaaaacatta caaatttact ttgcttcatg 4250

 taattttacg agttggcaat attttcttaa attggaatac tctaagagaa 4300

 taggacatgg atatgttaca agaagaagtg tattggggca agtcttgttt 4350

 ttctgaaggg aaatgccacc ggcctgcttt cataggcatt gataaagcca 4400

 ggaaggaaat aaagtcacaa ccaaatagta tacactgtct ctactgaatt 4450

 cttctaattc cttcgcaaca gaagtctaaa tcctgcttag cctaaacata 4500

 tctatagcca gcgatgggca aattatattt gctgtcagca tgatagaata 4550

 agaagcagaa accccccagc agtggggtaa gattgcgcgc ttcatcccct 4600

 caaaatgcag ctcagcccca ctccctctcc atgcccatca aacaactgca 4650

 caatcacttg ttactgaatt tcccattcag cgttttgttt ctttctgtcc 4700

 atacttaaag accaaatcat ttgtttgctt tgaagaaaaa gcaaaaacaa 4750

 gaacaaaaac accaaatcat ttgaaatcac tgtccattaa aaaaaatcac 4800

 cagtggaact aaacagttga gtggtttggg atgtgttcgc catttctgtg 4850

 tttgacctac atggcctgta attctttgga ccattgtaac tgtgaactat 4900

 ggcttaatac tgttaaagac cccaaggctc cactctgtag ccaggtgcac 4950

 ctcaggctgc acaaataccc caccagaatg tcacaatcat tcattgctcc 5000

 agctactgag tgaacagggt gcaagacagc actggcttgg gttgtatttt 5050

 tgcagccagt taactttgca tcaggtctac acagtccttg cagcctttga 5100

 tttctccagt tgtagagatt tgaaatgggg tgcccgggtt gctctcgttt 5150

 ttccttcaag ctacctagca tgcattttac acacattgga ggagtcgtat 5200

 gcactgtttt tctgttgctg atggaggcaa gcaggccttc taattagtct 5250

 aagttaaacg gatgggattc acttaagaaa agcaagaaga aaagcacacg 5300

 aacaggtgtc ttaatgcatt tggatagttt ctttgcgggg tgtgtgtgtg 5350

 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtc ttggtgaagg tgaggggctg 5400

 tattttcacc aagccttttc ataatcaagt ttgctttgca aaccttatgg 5450

 ccttgcaccc cgcagaacag tcccttccta atagcaggga tgctctgtca 5500

 tggtttttct gtaaattatc gtgtgttggg aagttctgtt gaggcttagt 5550

 ttgatcttcc atggtggaca cgtctgttct gtatgtaaaa ggcattacaa 5600

 ttgtgtttta gcagatgaga cttgaagcct ttccacagtc cttgtgctct 5650

 gagatggctg ttgagctctg ctcaactgtc gtagctgaat tctttctttg 5700

 cgctgaacac tgggcagcct caccatgttg ccaacgtgct tctggggccc 5750

 ctgtcactgc cgctggatgc cgcgcacaca ggcagagtgc cttggcaggt 5800

 ttgtgcaccc cttggcgagc cagaactggg aaccccgcgg ggtgacccct 5850

 tctcatgggg ggtcggggag gggagtgcct atttttaatc ctgtctgttt 5900

 gttgcacaat ggaaatcact gtgatttgta catatgccct aggaaaattt 5950

 tactgctgtc taatttatgt aataatactg ttgattccag gtttatttaa 6000

 taaaactttg tatcttttca gaaaaaaaaa aaaa 6034

<210> 1050
<211> 358
<212> PRT
<213> Homo sapien

<400> 1050
 Met Glu Ala Pro Gly Leu Ala Gln Ala Ala Ala Ala Glu Ser Asp
   1               5                  10                  15

 Ser Arg Lys Val Ala Glu Glu Thr Pro Asp Gly Ala Pro Ala Leu
                  20                  25                  30

 Cys Pro Ser Pro Glu Ala Leu Ser Pro Glu Pro Pro Val Tyr Ser
                  35                  40                  45

 Leu Gln Asp Phe Asp Thr Leu Ala Thr Val Gly Thr Gly Thr Phe
                  50                  55                  60

 Gly Arg Val His Leu Val Lys Glu Lys Thr Ala Lys His Phe Phe
                  65                  70                  75

 Ala Leu Lys Val Met Ser Ile Pro Asp Val Ile Arg Leu Lys Gln
                  80                  85                  90

 Glu Gln His Val His Asn Glu Lys Ser Val Leu Lys Glu Val Ser
                  95                 100                 105

 His Pro Phe Leu Ile Arg Leu Phe Trp Thr Trp His Asp Glu Arg
                 110                 115                 120

 Phe Leu Tyr Met Leu Met Glu Tyr Val Pro Gly Gly Glu Leu Phe
                 125                 130                 135

 Ser Tyr Leu Arg Asn Arg Gly Arg Phe Ser Ser Thr Thr Gly Leu
                 140                 145                 150

 Phe Tyr Ser Ala Glu Ile Ile Cys Ala Ile Glu Tyr Leu His Ser
                 155                 160                 165

 Lys Glu Ile Val Tyr Arg Asp Leu Lys Pro Glu Asn Ile Leu Leu
                 170                 175                 180

 Asp Arg Asp Gly His Ile Lys Leu Thr Asp Phe Gly Phe Ala Lys
                 185                 190                 195

 Lys Leu Val Asp Arg Thr Trp Thr Leu Cys Gly Thr Pro Glu Tyr
                 200                 205                 210

 Leu Ala Pro Glu Val Ile Gln Ser Lys Gly His Gly Arg Ala Val
                 215                 220                 225

 Asp Trp Trp Ala Leu Gly Ile Leu Ile Phe Glu Met Leu Ser Gly
                 230                 235                 240

 Phe Pro Pro Phe Phe Asp Asp Asn Pro Phe Gly Ile Tyr Gln Lys
                 245                 250                 255

 Ile Leu Ala Gly Lys Ile Asp Phe Pro Arg His Leu Asp Phe His
                 260                 265                 270

 Val Lys Asp Leu Ile Lys Lys Leu Leu Val Val Asp Arg Thr Arg
                 275                 280                 285

 Arg Leu Gly Asn Met Lys Asn Gly Ala Asn Asp Val Lys His His
                 290                 295                 300

 Arg Trp Phe Arg Ser Val Asp Trp Glu Ala Val Pro Gln Arg Lys
                 305                 310                 315

 Leu Lys Pro Pro Ile Val Pro Lys Ile Ala Gly Asp Gly Asp Thr
                 320                 325                 330

 Ser Asn Phe Glu Thr Tyr Pro Glu Asn Asp Trp Asp Thr Ala Ala
                 335                 340                 345

 Pro Val Pro Gln Lys Asp Leu Glu Ile Phe Lys Asn Phe
                 350                 355

<210> 1051
<211> 768
<212> DNA
<213> Homo sapien

<400> 1051
 ccttcagcat aaaagctgat ccacaaacaa gaggagcacc agacctcctc 50

 ttggcttcga gatggcttcg ccacaccaag agcccaaacc tggagacctg 100

 attgagattt tccgccttgg ctatgagcac tgggccctgt atataggaga 150

 tggctacgtg atccatctgg ctcctccaag tgagtacccc ggggctggct 200

 cctccagtgt cttctcagtc ctgagcaaca gtgcagaggt gaaacggggg 250

 cgcctggaag atgtggtggg aggctgttgc tatcgggtca acaacagctt 300

 ggaccatgag taccaaccac ggcccgtgga ggtgatcatc agttctgcga 350

 aggagatggt tggtcagaag atgaagtaca gtattgtgag caggaactgt 400

 gagcactttg tcgcccagct gagatatggc aagtcccgct gtaaacaggt 450

 ggaaaaggcc aaggttgaag tcggtgtggc cacggcgctt ggaatcctgg 500

 ttgttgctgg atgctctttt gcgattagga gataccaaaa aaaagcaaca 550

 gcctgaagca gccacaaaat cctgtgttag aagcagctgt gggggtccca 600

 gtggagatga gcctccccca tgcctccagc agcctgaccc tcgtgccctg 650

 tctcaggcgt tctctagatc ctttcctctg tttccctctc tcgctggcaa 700

 aagtatgatc taattgaaac aagactgaag gatcaataaa cagccatctg 750

 ccccttcaaa aaaaaaaa 768

<210> 1052
<211> 164
<212> PRT
<213> Homo sapien

<400> 1052
 Met Ala Ser Pro His Gln Glu Pro Lys Pro Gly Asp Leu Ile Glu
   1               5                  10                  15

 Ile Phe Arg Leu Gly Tyr Glu His Trp Ala Leu Tyr Ile Gly Asp
                  20                  25                  30

 Gly Tyr Val Ile His Leu Ala Pro Pro Ser Glu Tyr Pro Gly Ala
                  35                  40                  45

 Gly Ser Ser Ser Val Phe Ser Val Leu Ser Asn Ser Ala Glu Val
                  50                  55                  60

 Lys Arg Gly Arg Leu Glu Asp Val Val Gly Gly Cys Cys Tyr Arg
                  65                  70                  75

 Val Asn Asn Ser Leu Asp His Glu Tyr Gln Pro Arg Pro Val Glu
                  80                  85                  90

 Val Ile Ile Ser Ser Ala Lys Glu Met Val Gly Gln Lys Met Lys
                  95                 100                 105

 Tyr Ser Ile Val Ser Arg Asn Cys Glu His Phe Val Ala Gln Leu
                 110                 115                 120

 Arg Tyr Gly Lys Ser Arg Cys Lys Gln Val Glu Lys Ala Lys Val
                 125                 130                 135

 Glu Val Gly Val Ala Thr Ala Leu Gly Ile Leu Val Val Ala Gly
                 140                 145                 150

 Cys Ser Phe Ala Ile Arg Arg Tyr Gln Lys Lys Ala Thr Ala
                 155                 160

<210> 1053
<211> 10709
<212> DNA
<213> Homo sapien

<400> 1053
 agggggcggc gctcccggcc catcccttag ccccgcggcg gccgtgtggg 50

 ccggaggctg cctgcaccgc gtcagggagg ccggcctaga aaccctccct 100

 cccagaagaa agccgatccc agttcaggtg gggtcttcct cggttgcgta 150

 cctggctgga gccgagctgg tgggcggccg gcagccggcg tttctggtga 200

 tgacagcccc gaaatgaaag cagcgcggcc gccgcctccg agggctgcag 250

 ggagatcagc gtccagcaaa taagaagcaa gtcctggacc cggaggagga 300

 ggagcggccg agcatctctc tctgctccgc cgtgtccttt agatgagcac 350

 tcccggccgg agccggaggt ggatccgcag agctgcctct gggcgcctga 400

 ccccgcgctg acatcacaac ctgtgacagg cgcatcacgc ccggtacctg 450

 ctcccggccg ctgcccgtcc tcccagcctc tttgtatgcc gcagacatgg 500

 ccagccagca ggattcgggc ttctttgaga tcagtatcaa atatttactg 550

 aaatcctgga gtaatacttc tcccgttggc aacggttaca tcaagcctcc 600

 ggttccacct gcttctggca cgcacaggga gaaagggccg ccaaccatgc 650

 tacccatcaa tgtggaccca gacagtaaac caggagaata tgtcctcaaa 700

 agtttatttg tcaacttcac cactcaggct gaacgcaaga ttcgtatcat 750

 tatggcagag cccctggaaa agccattgac gaaatctctg caacgtggag 800

 aagaccccca atttgatcag gtcatcagct caatgagctc cctttctgag 850

 tactgcctgc cttccattct acgtacatta tttgactggt ataaaaggca 900

 aaatggcatt gaggatgaat cacatgaata cagaccaaga acaagcaata 950

 aatcaaaaag cgatgaacaa cagcgagatt atttaatgga aagacgggac 1000

 ctcgccattg attttatttt ttctttagta ttaatagaag ttttgaaaca 1050

 gattccactt catcctgtaa tagacagttt aatacatgat gttattaact 1100

 tggctttcaa gcactttaaa tacaaagaag ggtaccttgg tcccaacact 1150

 ggcaatatgc atattgtggc agacctgtat gcagaagtca ttggagtgtt 1200

 ggcacaagcc aaattccctg ctgtaaagaa gaaatttatg gcggagctaa 1250

 aagaattacg gcacaaagag cagaacccat atgtggttca aagcattatc 1300

 agcttaataa tgggcatgaa attctttcga attaagatgt atccagtgga 1350

 ggattttgag gcctctcttc agtttatgca ggaatgtgca cattacttcc 1400

 tcgaggtcaa agacaaagat atcaagcatg ccttggctgg gctttttgtt 1450

 gaaatacttg ttccagttgc tgctgctgtt aaaaatgaag taaatgttcc 1500

 ctgccttaga aattttgtgg aaagcctgta tgacaccacg ctggaacttt 1550

 cttctcgaaa gaagcattcc ttggccttgt accccctggt gacctgtttg 1600

 ctctgtgtca gtcagaagca gctgttcctg aacaggtggc acattttcct 1650

 caacaactgc ttgtccaacc ttaaaaacaa agatcccaag atggctcgag 1700

 ttgcactgga atctctctac agattacttt gggtttacat gattcgaatt 1750

 aaatgtgaaa gcaacacagc tactcagagc cgacttataa ccatcatcac 1800

 aacacttttc cccaaagggt cccgcggtgt ggtaccaagg gacatgcctc 1850

 tgaacatctt tgtgaaaatc atccagttca ttgcccagga acgtttagat 1900

 tttgcaatga aagaaatcat tttcgatttt ctttgtgtgg gaaaaccagc 1950

 aaaagcattc agtctcaacc cagagagaat gaacattggt ttacgggcat 2000

 tcttggtcat agctgatagc ttgcagcaga aagatgggga acctcccatg 2050

 ccggttacag gagccgttct tccttcagga aacacgttaa gagtaaagaa 2100

 aacatatttg agtaaaacac taactgaaga ggaagccaaa atgataggca 2150

 tgtccttata ttactctcaa gtacgaaaag ctgtagacaa cattttaagg 2200

 caccttgata aagaagtagg aaggtgtatg atgctgacta atgtacagat 2250

 gttaaacaaa gaaccggaag acatgatcac gggtgagaga aagccaaaaa 2300

 tagatctttt caggacctgt gttgctgcta ttcctcgact gcttcctgat 2350

 gggatgtcaa aacttgaact tattgactta ctggctaggc tctctattca 2400

 tatggatgat gaattgcgac atattgcaca aaattctctt cagggtttac 2450

 ttgttgactt ctcagattgg agggaagatg tactatttgg ctttaccaac 2500

 ttcctgctcc gggaagtaaa tgatatgcat cacacactcc ttgattcgtc 2550

 cctgaagttg ctgctgcagc tgctcaccca gtggaaacta gtcatccaga 2600

 cacaaggaaa agtctatgaa caagccaaca aaatcagaaa ttcagagctc 2650

 atcgcaaatg gctccagtca cagaattcag tcggaacgag gtccccactg 2700

 cagtgtactc cacgctgtag aaggttttgc tctggtttta ctctgcagtt 2750

 tccaggtggc cacacgcaaa ctgtccgttt taatactcaa ggaaattcga 2800

 gcgttgttta ttgccctggg gcagcctgag gatgacgaca ggccgatgat 2850

 tgatgtcatg gatcagctaa gttcttccat tctagaaagt tttattcatg 2900

 tagcagtttc ggattcagca acattaccac tcacccacaa tgtggatctg 2950

 cagtggttgg tggaatggaa cgcagtcctg gtcaatagcc attatgatgt 3000

 gaaaagccct tcccatgtct ggatatttgc acagtctgtc aaagacccct 3050

 gggtcctctg cctcttcagc ttcctccggc aggagaactt acccaagcac 3100

 tgccccacag ccctcagcta tgcctggcct tatgccttca ctcggctcca 3150

 gtcggtgatg cctctggtgg acccaaatag cccaattaat gccaagaaaa 3200

 ccagcactgc cggcagcgga gacaactatg ttactttgtg gagaaattac 3250

 ctaattcttt gttttggagt tgcaaaaccc agtattatga gcccaggaca 3300

 cttaagagct tccactccag aaataatggc gaccacacct gatggtacag 3350

 tgagctacga taacaaggcc ataggcaccc catcggtggg agttctgtta 3400

 aagcagttgg tgcctttgat gagactagag agcattgaga tcacagagtc 3450

 cttagtttta ggatttggaa gaacaaattc ccttgttttc agagaattgg 3500

 tagaagaact tcatccatta atgaaagaag ctctggaaag aagaccagag 3550

 aacaagaaac gccgagaacg gcgagacttg ttaaggctac aactacttcg 3600

 aatttttgaa cttttggctg atgctggtgt aataagtgac agcacaaatg 3650

 gagccctaga gcgggatact ttagccctgg gagctttgtt cttagaatat 3700

 gtggacttga cccgcatgct cctagaagct gaaaatgaca aagaagttga 3750

 aattcttaaa gatatccggg cacattttag tgcaatggtg gccaacttga 3800

 ttcagtgtgt tccagttcac caccgaagat ttctcttccc ccagcaaagt 3850

 ctgaggcacc accttttcat cttattcagc cagtgggcag gacccttcag 3900

 cattatgttc actcctctgg atcgttacag tgacagaaat catcagatta 3950

 caagatatca gtattgtgca ttaaaagcaa tgtcagcagt actgtgctgt 4000

 ggccctgtct ttgacaatgt gggcctttcc ccagatggct acctatataa 4050

 atggcttgac aacattctgg cttgtcaaga tttacgagtt catcaacttg 4100

 gctgcgaagt tgttgtcttg ctactggaac ttaatcctga ccaaataaat 4150

 ctttttaact gggcaattga ccgatgctac acaggttcct accaacttgc 4200

 atctggctgc ttcaaagcca tagcaactgt gtgtggaagc aggaactatc 4250

 ccttcgacat agtgacattg ttaaaccttg ttctattcaa ggcctctgac 4300

 accaacagag agatttatga aatctccatg cagctcatgc agatccttga 4350

 agcaaagctt tttgtatact caaagaaagt cgctgagcaa agaccgggaa 4400

 gtattctcta tggaacacac ggcccgctgc cacccctcta cagcgtgtca 4450

 ctcgccctct tgtcatgtga gctggccagg atgtaccctg agctcacact 4500

 ccccctcttc tcaggtaagc cagcgattcc ccacaacaca ccccaacggg 4550

 cgccagatca tgcttaccta cctgctgccc tggctgcaca acatcgagct 4600

 ggtggacagc aggctcctcc tcccgggtcg agccccagca gcccagagga 4650

 cgaagtcaag gaccgggaag gtgacgtgac tgcttctcac gggctgagag 4700

 gaaatggctg gggctctcca gaagccacgt cactggtcct gaacaacctc 4750

 atgtacatga cggccaagta tggagatgaa gttcctgggc cagaaatgga 4800

 aaatgcttgg aatgctttag ccaacaatga gaaatggagc aacaacctga 4850

 ggatcacctt gcagttcctg attagcctct gtggggtcag cagcgacaca 4900

 gttctcctac cctatattaa aaaagtggca atatacttgt gccgtaacaa 4950

 caccattcaa accatggaag agcttctctt tgagctgcag cagacagaac 5000

 ccgtgaaccc catcgtccag cattgtgaca acccgccctt ctaccgcttc 5050

 acggccagta gcaaggcttc cgcagcagcc tcaggaacca cctctagcag 5100

 caatacagtg gttgctggcc aggaaaattt cccagatgct gaggagaaca 5150

 agatattgaa agaatctgat gaaaggttta gtaatgtcat cagagcccac 5200

 actcgcctcg agtcaagata cagcaatagc tctggaggat cctacgatga 5250

 agataaaaat gatccaattt ctccctacac gggctggttg ctgactatta 5300

 cagagaccaa gcagccgcag cccttaccga tgccttgtac tggaggatgc 5350

 tgggcccccc tggttgacta tctcccggag accatcactc cccgggggcc 5400

 actccacagg tgcaatattg ctgtaatttt tatgactgaa atggtggtgg 5450

 atcacagtgt acgagaagac tgggcgcttc atctaccatt attacttcat 5500

 gctgtcttct taggtttaga ccactaccgg cctgaagtct ttgaacacag 5550

 caaaaaactg cttcttcacc tcttgattgc cctctcttgc aacagcaatt 5600

 tccattccat tgcttccgtg ctcctgcaga cccgagagat gggtgaagct 5650

 aagactctaa ccgtgcagcc agcctaccaa cctgaatatc tctatacagg 5700

 tggctttgac ttcctgagag aggaccagtc atccccggtg cctgactcag 5750

 ggcttagttc aagctccacc tcctctagca tcagtctggg aggcagcagt 5800

 ggaaacctcc cacagatgac ccaggaggta gaagatgtgg acacagctgc 5850

 tgaaacagat gagaaggcaa acaagctcat tgagtttctc acgaccaggg 5900

 catttggtcc actttggtgc catgaagaca tcacacctaa aaatcaaaat 5950

 tcaaagagtg ctgaacagct cactaatttt ctacgtcacg ttgtatctgt 6000

 atttaaagat tccaaatcag gcttccatct ggagcaccag ttgagtgaag 6050

 ttgcattgca gacagccctc gcaagctctt caaggcacta tgctggtcgg 6100

 tccttccaga tattccgggc cctcaagcaa cctctgtcag cacatgcctt 6150

 atctgacctt ctctcaagat tggtggaggt gataggagaa catggagatg 6200

 agattcaggg ttatgtaatg gaagcgctcc taaccttgga ggcggctgtg 6250

 gataacttgt ctgactgctt gaagaacagt gacctcctaa ctgtattgtc 6300

 ccgctcttcc tcaccagatt taagctccag cagtaaacta acagcaagca 6350

 gaaagagcac aggacaacta aacatgaacc cgggaaccac cagcggcaac 6400

 accgcaactg ccgaacggag ccggcatcaa cgaagcttct ctgtgcccaa 6450

 gaagtttggt gtcatcgacc gatcctctga cccacctcga agtgccacac 6500

 tggacagaat tcaggcttgt acccaacaag gcctctcctc aaaaaccaga 6550

 agctcatcct ccttgaagga cagtctcacg gacccatccc acataaacca 6600

 tcccaccaac ctgctggcca ccatattctg ggtcacagtg gccttgatgg 6650

 agtctgattt tgagtttgaa tacttaatgg ccttaaggct gttgagcaga 6700

 ctactggcac atatgccact cgataaggct gagaaccgag aaaagcttga 6750

 gaaactccag gcacagctga agtgggccga cttctccggg ctgcagcagc 6800

 tgctgctgaa aggattcaca tccctcacca ccacagacct gaccctgcag 6850

 ctcttcagtc tgctgacacc agtgtccaaa atatccatgg tggatgcatc 6900

 ccacgctatt gggtttccac tgaatgtctt gtgtctcctg cctcagctga 6950

 ttcagcattt tgaaaatccc aatcagttct gtaaggatat agccgaaagg 7000

 attgctcagg tttgtttaga agagaagaac cccaaacttt caaatcttgc 7050

 acatgtcatg actctttata aaacgcacag ctacacgagg gactgtgcca 7100

 cgtgggtcaa tgtggtctgt cgataccttc atgaagcata tgctgacatt 7150

 accttgaata tggttaccta cctggcagag ctgctggaga agggcctccc 7200

 tagtgtgcag cagcccctgc tccaggtgat ctacagtctt ctcagctaca 7250

 tggacctttc tgtcgttcct gtcaaacagt tcaatgtgga agttctgaag 7300

 acaattgaaa aatatgtgca aagtgttcac tggagagaag ctctgaatat 7350

 cttgaagctg gtagtttctc ggtcagccag ccttgtttta ccttcatacc 7400

 agcacagtga cctctcaaaa atagaaatac atcgagtgtg gactagtgct 7450

 tccaaggaat tacctgggaa aaccctggac ttccacttcg atatttcgga 7500

 gactccaatc atcgggaggc ggtatgatga gctgcagaat tcttctgggc 7550

 gtgatgggaa gcccagggcc atggccgtca cccggagcac atcttccact 7600

 tcctcaggct ccaactccaa cgtccttgtt ccagtgagct ggaaaaggcc 7650

 ccagtattct cagaagagaa caaaagagaa gttggtacat gtcctttctc 7700

 tgtgtggcca agaagtagga ttgagcaaaa atccatcagt gattttttca 7750

 tcgtgtgggg atctggatct gcttgagcac cagacaagct tggtatcttc 7800

 tgaggacggt gcccgagagc aggagaacat ggatgacaca aacagcgagc 7850

 agcagtttag agtcttcaga gacttcgact tcctagatgt ggagctggag 7900

 gatggagagg gtgagagtat ggacaatttc aactggggag tgcgcagacg 7950

 ttctctggac agcctggata agtgtgatat gcagattctg gaggagcgcc 8000

 aactgtcagg aagcactcct agcctgaata aaatgcacca tgaggactcc 8050

 gatgaatcat ccgaggagga ggacctcaca gccagccaga tcctggagca 8100

 ctcagaccta atcatgactc tctccccctc tgaagagacg aatcccatgg 8150

 agctgctcac cacagcctgt gactcgaccc ctgcagaacc tcattccttt 8200

 aacaccagaa tgtccagctt tgatgcttcc ttgcctgata tgaataatct 8250

 gcagatttct gagggttcaa aggctgaagc tgttcgtgag gaggaggaca 8300

 ccaccgtgca tgaggatgat ctttctagtt ccatcaatga actcccagca 8350

 gcttttgaat gcagcgacag ctttagcctg gacatgactg agggggaaga 8400

 aaaaggcaat cgggcactgg accagtttac cctggcgagc tttggagaag 8450

 gtgacagggg agtctctccc cctccctcgc ccttcttctc agccatcctt 8500

 gccgcctttc agcccgcagc ctgtgacgat gccgaggagg cctggcgcag 8550

 ccacatcaac cagcttatgt gtgactcaga tggctcctgt gctgtgtata 8600

 catttcatgt gttctcctcc ttgtttaaga atattcagaa aaggttctgc 8650

 ttcctaacct gtgatgcagc cagttacctt ggagataacc tccggggaat 8700

 cggatccaaa tttgtcagct cttcccagat gctcacctcc tgctctgaat 8750

 gtcctacact ttttgtggat gccgagactc tcctttcatg tggacttctg 8800

 gacaagctca agttcagtgt gttagaactg caagaatatt tggataccta 8850

 caacaacagg aaagaggcca cactctcttg gcttgcaaat tgtaaggcaa 8900

 catttgcagg gggatcaaga gatggagtaa ttacctgtca accaggggac 8950

 tccgaagaaa agcaattgga actgtgtcag agattatata agctacactt 9000

 ccagctgcta ttgctttttc agtcctactg taagctcatc ggccaggtgc 9050

 acgaagttag ctccatgcca gagctgctga atatgtccag ggaactgagt 9100

 gacctaaaga aacacctgaa ggaagccagt gcagtcattg cagctgaccc 9150

 tctctattca gacggcgcgt ggtccgagcc caccttcacg tccactgaag 9200

 cagccatcca gtccatgctg gagtgcctga agaacaacga actcggcaaa 9250

 gctttgcggc agatcaggga gtgcagaagt ctgtggccca atgacatctt 9300

 tggaagcagt tctgatgatg aggtccagac actactgaat atttatttcc 9350

 gtcaccaaac tctgggacag acgggtactt atgccctggt ggggtctaac 9400

 cagagcctga ccgagatctg caccaagctg atggagctga acatggagat 9450

 ccgggacatg atccgcaggg cccagagtta ccgagtcctc actacttttc 9500

 ttccagactc cagtgtttct ggcactagtc tctgacagga gcctcctgtc 9550

 cccactgggt tccaaactgc agtgctgcca tgctggggca acgtcattca 9600

 gtgtcttctc ggccttcaaa aggcttggac agactgttct ccctcttgtt 9650

 acctgtaggg ctttttctaa agaggatggc agaacttcca acgtgtagca 9700

 atactataag aaccaaggta gcttagaacg tcctggacag actccactca 9750

 tcatgctgtg tggcacaaat gtgttacatt tgaccgagca tatgcaactc 9800

 gctactgaag aagtgacttc cgttgcatac caaagccgac tacactgaac 9850

 agtaccttcc tttctagaaa caattttaga ttggcaaaag tgcaatgttt 9900

 tcttcactca aaaaatttta tattctcaaa catgtatatt ctttccctgt 9950

 cttgttccat tttcttttct tttttctttt ttctttttcc tttctttcgt 10000

 gggctgagaa aggggcaggc aaaatgaagc tggccactga aaactgtaag 10050

 atggtcaaaa gctgacagcc tgtgtatgtg aaaagggaat tgtaaatgga 10100

 ctgcaatgta atgtacactg taatttgaat acaattactg tatctaaaag 10150

 gagctgctat gaagtacctt tcttatgttg ctaggctact gtttctgaaa 10200

 gccctggatc tctttgcacc aaaaatggtc cagatagact ctttttaagg 10250

 atcttggctg ctttttacta gaaggttgct tttatgagca tatttatact 10300

 gctgaaggat gagtgttaat tttaattaac tttgccgttt tgtagagaaa 10350

 actattcaca agataaattc caagtctttt cacctgtcag gcatgcatat 10400

 tttaatatct gtttggatag tcagaagtag aatcataaag gtaaaatatg 10450

 agttgttact ttgtttcttc gatgtcatat tttatgtgta atatatatgt 10500

 aaagggccat tcttaagttc tctccttaaa cttaatgctg tcaagtgtta 10550

 gatgtgtgca tgtgaacttg ttgcactgca gaaacatatt cagagtttat 10600

 ctatgtaact tattcactct gtaaatacat ttaaagtttt tgtgatgtaa 10650

 gcttaattga tattctgttc agaactttct ttagactaaa aaaaaaaaaa 10700

 aaagacaaa 10709

<210> 1054
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1054
 Met Ala Ser Gln Gln Asp Ser Gly Phe Phe Glu Ile Ser Ile Lys
   1               5                  10                  15

 Tyr Leu Leu Lys Ser Trp Ser Asn Thr Ser Pro Val Gly Asn Gly
                  20                  25                  30

 Tyr Ile Lys Pro Pro Val Pro Pro Ala Ser Gly Thr His Arg Glu
                  35                  40                  45

 Lys Gly Pro Pro Thr Met Leu Pro Ile Asn Val Asp Pro Asp Ser
                  50                  55                  60

 Lys Pro Gly Glu Tyr Val Leu Lys Ser Leu Phe Val Asn Phe Thr
                  65                  70                  75

 Thr Gln Ala Glu Arg Lys Ile Arg Ile Ile Met Ala Glu Pro Leu
                  80                  85                  90

 Glu Lys Pro Leu Thr Lys Ser Leu Gln Arg Gly Glu Asp Pro Gln
                  95                 100                 105

 Phe Asp Gln Val Ile Ser Ser Met Ser Ser Leu Ser Glu Tyr Cys
                 110                 115                 120

 Leu Pro Ser Ile Leu Arg Thr Leu Phe Asp Trp Tyr Lys Arg Gln
                 125                 130                 135

 Asn Gly Ile Glu Asp Glu Ser His Glu Tyr Arg Pro Arg Thr Ser
                 140                 145                 150

 Asn Lys Ser Lys Ser Asp Glu Gln Gln Arg Asp Tyr Leu Met Glu
                 155                 160                 165

 Arg Arg Asp Leu Ala Ile Asp Phe Ile Phe Ser Leu Val Leu Ile
                 170                 175                 180

 Glu Val Leu Lys Gln Ile Pro Leu His Pro Val Ile Asp Ser Leu
                 185                 190                 195

 Ile His Asp Val Ile Asn Leu Ala Phe Lys His Phe Lys Tyr Lys
                 200                 205                 210

 Glu Gly Tyr Leu Gly Pro Asn Thr Gly Asn Met His Ile Val Ala
                 215                 220                 225

 Asp Leu Tyr Ala Glu Val Ile Gly Val Leu Ala Gln Ala Lys Phe
                 230                 235                 240

 Pro Ala Val Lys Lys Lys Phe Met Ala Glu Leu Lys Glu Leu Arg
                 245                 250                 255

 His Lys Glu Gln Asn Pro Tyr Val Val Gln Ser Ile Ile Ser Leu
                 260                 265                 270

 Ile Met Gly Met Lys Phe Phe Arg Ile Lys Met Tyr Pro Val Glu
                 275                 280                 285

 Asp Phe Glu Ala Ser Leu Gln Phe Met Gln Glu Cys Ala His Tyr
                 290                 295                 300

 Phe Leu Glu Val Lys Asp Lys Asp Ile Lys His Ala Leu Ala Gly
                 305                 310                 315

 Leu Phe Val Glu Ile Leu Val Pro Val Ala Ala Ala Val Lys Asn
                 320                 325                 330

 Glu Val Asn Val Pro Cys Leu Arg Asn Phe Val Glu Ser Leu Tyr
                 335                 340                 345

 Asp Thr Thr Leu Glu Leu Ser Ser Arg Lys Lys His Ser Leu Ala
                 350                 355                 360

 Leu Tyr Pro Leu Val Thr Cys Leu Leu Cys Val Ser Gln Lys Gln
                 365                 370                 375

 Leu Phe Leu Asn Arg Trp His Ile Phe Leu Asn Asn Cys Leu Ser
                 380                 385                 390

 Asn Leu Lys Asn Lys Asp Pro Lys Met Ala Arg Val Ala Leu Glu
                 395                 400                 405

 Ser Leu Tyr Arg Leu Leu Trp Val Tyr Met Ile Arg Ile Lys Cys
                 410                 415                 420

 Glu Ser Asn Thr Ala Thr Gln Ser Arg Leu Ile Thr Ile Ile Thr
                 425                 430                 435

 Thr Leu Phe Pro Lys Gly Ser Arg Gly Val Val Pro Arg Asp Met
                 440                 445                 450

 Pro Leu Asn Ile Phe Val Lys Ile Ile Gln Phe Ile Ala Gln Glu
                 455                 460                 465

 Arg Leu Asp Phe Ala Met Lys Glu Ile Ile Phe Asp Phe Leu Cys
                 470                 475                 480

 Val Gly Lys Pro Ala Lys Ala Phe Ser Leu Asn Pro Glu Arg Met
                 485                 490                 495

 Asn Ile Gly Leu Arg Ala Phe Leu Val Ile Ala Asp Ser Leu Gln
                 500                 505                 510

 Gln Lys Asp Gly Glu Pro Pro Met Pro Val Thr Gly Ala Val Leu
                 515                 520                 525

 Pro Ser Gly Asn Thr Leu Arg Val Lys Lys Thr Tyr Leu Ser Lys
                 530                 535                 540

 Thr Leu Thr Glu Glu Glu Ala Lys Met Ile Gly Met Ser Leu Tyr
                 545                 550                 555

 Tyr Ser Gln Val Arg Lys Ala Val Asp Asn Ile Leu Arg His Leu
                 560                 565                 570

 Asp Lys Glu Val Gly Arg Cys Met Met Leu Thr Asn Val Gln Met
                 575                 580                 585

 Leu Asn Lys Glu Pro Glu Asp Met Ile Thr Gly Glu Arg Lys Pro
                 590                 595                 600

 Lys Ile Asp Leu Phe Arg Thr Cys Val Ala Ala Ile Pro Arg Leu
                 605                 610                 615

 Leu Pro Asp Gly Met Ser Lys Leu Glu Leu Ile Asp Leu Leu Ala
                 620                 625                 630

 Arg Leu Ser Ile His Met Asp Asp Glu Leu Arg His Ile Ala Gln
                 635                 640                 645

 Asn Ser Leu Gln Gly Leu Leu Val Asp Phe Ser Asp Trp Arg Glu
                 650                 655                 660

 Asp Val Leu Phe Gly Phe Thr Asn Phe Leu Leu Arg Glu Val Asn
                 665                 670                 675

 Asp Met His His Thr Leu Leu Asp Ser Ser Leu Lys Leu Leu Leu
                 680                 685                 690

 Gln Leu Leu Thr Gln Trp Lys Leu Val Ile Gln Thr Gln Gly Lys
                 695                 700                 705

 Val Tyr Glu Gln Ala Asn Lys Ile Arg Asn Ser Glu Leu Ile Ala
                 710                 715                 720

 Asn Gly Ser Ser His Arg Ile Gln Ser Glu Arg Gly Pro His Cys
                 725                 730                 735

 Ser Val Leu His Ala Val Glu Gly Phe Ala Leu Val Leu Leu Cys
                 740                 745                 750

 Ser Phe Gln Val Ala Thr Arg Lys Leu Ser Val Leu Ile Leu Lys
                 755                 760                 765

 Glu Ile Arg Ala Leu Phe Ile Ala Leu Gly Gln Pro Glu Asp Asp
                 770                 775                 780

 Asp Arg Pro Met Ile Asp Val Met Asp Gln Leu Ser Ser Ser Ile
                 785                 790                 795

 Leu Glu Ser Phe Ile His Val Ala Val Ser Asp Ser Ala Thr Leu
                 800                 805                 810

 Pro Leu Thr His Asn Val Asp Leu Gln Trp Leu Val Glu Trp Asn
                 815                 820                 825

 Ala Val Leu Val Asn Ser His Tyr Asp Val Lys Ser Pro Ser His
                 830                 835                 840

 Val Trp Ile Phe Ala Gln Ser Val Lys Asp Pro Trp Val Leu Cys
                 845                 850                 855

 Leu Phe Ser Phe Leu Arg Gln Glu Asn Leu Pro Lys His Cys Pro
                 860                 865                 870

 Thr Ala Leu Ser Tyr Ala Trp Pro Tyr Ala Phe Thr Arg Leu Gln
                 875                 880                 885

 Ser Val Met Pro Leu Val Asp Pro Asn Ser Pro Ile Asn Ala Lys
                 890                 895                 900

 Lys Thr Ser Thr Ala Gly Ser Gly Asp Asn Tyr Val Thr Leu Trp
                 905                 910                 915

 Arg Asn Tyr Leu Ile Leu Cys Phe Gly Val Ala Lys Pro Ser Ile
                 920                 925                 930

 Met Ser Pro Gly His Leu Arg Ala Ser Thr Pro Glu Ile Met Ala
                 935                 940                 945

 Thr Thr Pro Asp Gly Thr Val Ser Tyr Asp Asn Lys Ala Ile Gly
                 950                 955                 960

 Thr Pro Ser Val Gly Val Leu Leu Lys Gln Leu Val Pro Leu Met
                 965                 970                 975

 Arg Leu Glu Ser Ile Glu Ile Thr Glu Ser Leu Val Leu Gly Phe
                 980                 985                 990

 Gly Arg Thr Asn Ser Leu Val Phe Arg Glu Leu Val Glu Glu Leu
                 995                1000                1005

 His Pro Leu Met Lys Glu Ala Leu Glu Arg Arg Pro Glu Asn Lys
                1010                1015                1020

 Lys Arg Arg Glu Arg Arg Asp Leu Leu Arg Leu Gln Leu Leu Arg
                1025                1030                1035

 Ile Phe Glu Leu Leu Ala Asp Ala Gly Val Ile Ser Asp Ser Thr
                1040                1045                1050

 Asn Gly Ala Leu Glu Arg Asp Thr Leu Ala Leu Gly Ala Leu Phe
                1055                1060                1065

 Leu Glu Tyr Val Asp Leu Thr Arg Met Leu Leu Glu Ala Glu Asn
                1070                1075                1080

 Asp Lys Glu Val Glu Ile Leu Lys Asp Ile Arg Ala His Phe Ser
                1085                1090                1095

 Ala Met Val Ala Asn Leu Ile Gln Cys Val Pro Val His His Arg
                1100                1105                1110

 Arg Phe Leu Phe Pro Gln Gln Ser Leu Arg His His Leu Phe Ile
                1115                1120                1125

 Leu Phe Ser Gln Trp Ala Gly Pro Phe Ser Ile Met Phe Thr Pro
                1130                1135                1140

 Leu Asp Arg Tyr Ser Asp Arg Asn His Gln Ile Thr Arg Tyr Gln
                1145                1150                1155

 Tyr Cys Ala Leu Lys Ala Met Ser Ala Val Leu Cys Cys Gly Pro
                1160                1165                1170

 Val Phe Asp Asn Val Gly Leu Ser Pro Asp Gly Tyr Leu Tyr Lys
                1175                1180                1185

 Trp Leu Asp Asn Ile Leu Ala Cys Gln Asp Leu Arg Val His Gln
                1190                1195                1200

 Leu Gly Cys Glu Val Val Val Leu Leu Leu Glu Leu Asn Pro Asp
                1205                1210                1215

 Gln Ile Asn Leu Phe Asn Trp Ala Ile Asp Arg Cys Tyr Thr Gly
                1220                1225                1230

 Ser Tyr Gln Leu Ala Ser Gly Cys Phe Lys Ala Ile Ala Thr Val
                1235                1240                1245

 Cys Gly Ser Arg Asn Tyr Pro Phe Asp Ile Val Thr Leu Leu Asn
                1250                1255                1260

 Leu Val Leu Phe Lys Ala Ser Asp Thr Asn Arg Glu Ile Tyr Glu
                1265                1270                1275

 Ile Ser Met Gln Leu Met Gln Ile Leu Glu Ala Lys Leu Phe Val
                1280                1285                1290

 Tyr Ser Lys Lys Val Ala Glu Gln Arg Pro Gly Ser Ile Leu Tyr
                1295                1300                1305

 Gly Thr His Gly Pro Leu Pro Pro Leu Tyr Ser Val Ser Leu Ala
                1310                1315                1320

 Leu Leu Ser Cys Glu Leu Ala Arg Met Tyr Pro Glu Leu Thr Leu
                1325                1330                1335

 Pro Leu Phe Ser Gly Lys Pro Ala Ile Pro His Asn Thr Pro Gln
                1340                1345                1350

 Arg Ala Pro Asp His Ala Tyr Leu Pro Ala Ala Leu Ala Ala Gln
                1355                1360                1365

 His Arg Ala Gly Gly Gln Gln Ala Pro Pro Pro Gly Ser Ser Pro
                1370                1375                1380

 Ser Ser Pro Glu Asp Glu Val Lys Asp Arg Glu Gly Asp Val Thr
                1385                1390                1395

 Ala Ser His Gly Leu Arg Gly Asn Gly Trp Gly Ser Pro Glu Ala
                1400                1405                1410

 Thr Ser Leu Val Leu Asn Asn Leu Met Tyr Met Thr Ala Lys Tyr
                1415                1420                1425

 Gly Asp Glu Val Pro Gly Pro Glu Met Glu Asn Ala Trp Asn Ala
                1430                1435                1440

 Leu Ala Asn Asn Glu Lys Trp Ser Asn Asn Leu Arg Ile Thr Leu
                1445                1450                1455

 Gln Phe Leu Ile Ser Leu Cys Gly Val Ser Ser Asp Thr Val Leu
                1460                1465                1470

 Leu Pro Tyr Ile Lys Lys Val Ala Ile Tyr Leu Cys Arg Asn Asn
                1475                1480                1485

 Thr Ile Gln Thr Met Glu Glu Leu Leu Phe Glu Leu Gln Gln Thr
                1490                1495                1500

 Glu Pro Val Asn Pro Ile Val Gln His Cys Asp Asn Pro Pro Phe
                1505                1510                1515

 Tyr Arg Phe Thr Ala Ser Ser Lys Ala Ser Ala Ala Ala Ser Gly
                1520                1525                1530

 Thr Thr Ser Ser Ser Asn Thr Val Val Ala Gly Gln Glu Asn Phe
                1535                1540                1545

 Pro Asp Ala Glu Glu Asn Lys Ile Leu Lys Glu Ser Asp Glu Arg
                1550                1555                1560

 Phe Ser Asn Val Ile Arg Ala His Thr Arg Leu Glu Ser Arg Tyr
                1565                1570                1575

 Ser Asn Ser Ser Gly Gly Ser Tyr Asp Glu Asp Lys Asn Asp Pro
                1580                1585                1590

 Ile Ser Pro Tyr Thr Gly Trp Leu Leu Thr Ile Thr Glu Thr Lys
                1595                1600                1605

 Gln Pro Gln Pro Leu Pro Met Pro Cys Thr Gly Gly Cys Trp Ala
                1610                1615                1620

 Pro Leu Val Asp Tyr Leu Pro Glu Thr Ile Thr Pro Arg Gly Pro
                1625                1630                1635

 Leu His Arg Cys Asn Ile Ala Val Ile Phe Met Thr Glu Met Val
                1640                1645                1650

 Val Asp His Ser Val Arg Glu Asp Trp Ala Leu His Leu Pro Leu
                1655                1660                1665

 Leu Leu His Ala Val Phe Leu Gly Leu Asp His Tyr Arg Pro Glu
                1670                1675                1680

 Val Phe Glu His Ser Lys Lys Leu Leu Leu His Leu Leu Ile Ala
                1685                1690                1695

 Leu Ser Cys Asn Ser Asn Phe His Ser Ile Ala Ser Val Leu Leu
                1700                1705                1710

 Gln Thr Arg Glu Met Gly Glu Ala Lys Thr Leu Thr Val Gln Pro
                1715                1720                1725

 Ala Tyr Gln Pro Glu Tyr Leu Tyr Thr Gly Gly Phe Asp Phe Leu
                1730                1735                1740

 Arg Glu Asp Gln Ser Ser Pro Val Pro Asp Ser Gly Leu Ser Ser
                1745                1750                1755

 Ser Ser Thr Ser Ser Ser Ile Ser Leu Gly Gly Ser Ser Gly Asn
                1760                1765                1770

 Leu Pro Gln Met Thr Gln Glu Val Glu Asp Val Asp Thr Ala Ala
                1775                1780                1785

 Glu Thr Asp Glu Lys Ala Asn Lys Leu Ile Glu Phe Leu Thr Thr
                1790                1795                1800

 Arg Ala Phe Gly Pro Leu Trp Cys His Glu Asp Ile Thr Pro Lys
                1805                1810                1815

 Asn Gln Asn Ser Lys Ser Ala Glu Gln Leu Thr Asn Phe Leu Arg
                1820                1825                1830

 His Val Val Ser Val Phe Lys Asp Ser Lys Ser Gly Phe His Leu
                1835                1840                1845

 Glu His Gln Leu Ser Glu Val Ala Leu Gln Thr Ala Leu Ala Ser
                1850                1855                1860

 Ser Ser Arg His Tyr Ala Gly Arg Ser Phe Gln Ile Phe Arg Ala
                1865                1870                1875

 Leu Lys Gln Pro Leu Ser Ala His Ala Leu Ser Asp Leu Leu Ser
                1880                1885                1890

 Arg Leu Val Glu Val Ile Gly Glu His Gly Asp Glu Ile Gln Gly
                1895                1900                1905

 Tyr Val Met Glu Ala Leu Leu Thr Leu Glu Ala Ala Val Asp Asn
                1910                1915                1920

 Leu Ser Asp Cys Leu Lys Asn Ser Asp Leu Leu Thr Val Leu Ser
                1925                1930                1935

 Arg Ser Ser Ser Pro Asp Leu Ser Ser Ser Ser Lys Leu Thr Ala
                1940                1945                1950

 Ser Arg Lys Ser Thr Gly Gln Leu Asn Met Asn Pro Gly Thr Thr
                1955                1960                1965

 Ser Gly Asn Thr Ala Thr Ala Glu Arg Ser Arg His Gln Arg Ser
                1970                1975                1980

 Phe Ser Val Pro Lys Lys Phe Gly Val Ile Asp Arg Ser Ser Asp
                1985                1990                1995

 Pro Pro Arg Ser Ala
                2000

<210> 1055
<211> 1855
<212> DNA
<213> Homo sapien

<400> 1055
 ctgggtgcgt ggggctgcct cgccgcgtct cgccacgggc tctgccagca 50

 gacagccttg gcacacaggc acaagggctg gagcccagag atgagagtgc 100

 ccaagggaga tgtgagcctg gcgggctgcc cgctaacctg tcgctgaagc 150

 cccagaagcg ggccctcagg ccaggcctac cctgcctccg gcccagcatg 200

 cgcctgtcgg tgcggagggt gctgctggca gccggctgcg ccctggtcct 250

 ggtgctggcg gttcagctgg gacagcaggt gctagagtgc cgggcggtgc 300

 tggcgggcct gcggagcccc cggggggcca tgcggcctga gcaggaggag 350

 ctggtgatgg tgggcaccaa ccacgtggaa taccgctatg gcaaggccat 400

 gccgctcatc ttcgtgggtg gcgtgcctcg cagtggcacc acgttgatgc 450

 gcgccatgct ggacgcccac cccgaggtgc gctgcggcga ggagacccgc 500

 atcatcccgc gcgtgctggc catgcgccag gcctggtcca agtctggccg 550

 tgagaagctg cggctggatg aggcgggggt gacggatgag gtgctggacg 600

 ccgccatgca ggccttcatc ctggaggtga ttgccaagca cggagagccg 650

 gcccgcgtgc tctgcaacaa ggacccattt acgctcaagt cctcggtcta 700

 cctgtcgcgc ctgttcccca actccaagtt cctgctgatg gtgcgggacg 750

 gccgggcctc cgtgcactcc atgatcacgc gcaaagtcac cattgcgggc 800

 tttgacctca gcagctaccg tgactgcctc accaagtgga acaaggccat 850

 cgaggtgatg tacgcccagt gcatggaggt aggcaaggag aagtgcttgc 900

 ctgtgtacta cgagcagctg gtgctgcacc ccaggcgctc actcaagctc 950

 atcctcgact tcctcggcat cgcctggagc gacgctgtcc tccaccatga 1000

 agacctcatt ggcaagcccg gtggtgtctc cctgtccaag atcgagcggt 1050

 ccacggacca ggtcatcaag cctgttaacc tggaagcgct ctccaagtgg 1100

 actggccaca tccctgggga tgtggtgcgg gacatggccc agatcgcccc 1150

 catgctggct cagctcggct atgaccctta tgcaaacccc cccaactatg 1200

 gcaaccctga ccccttcgtc atcaacaaca cacagcgggt cttgaaaggg 1250

 gactataaaa caccagccaa tctgaaagga tattttcagg tgaaccagaa 1300

 cagcacctcc tcccacttag gaagctcgtg atttccagat ctccgcaaat 1350

 gacttcattg ccaagaagag aagaaaatgc atttaagtgg aaatcggacc 1400

 tctaatccaa gcatattgct tgctattaat cgccaaaaca ggactgctga 1450

 tgaggaatgt atttgcatat gtttgcaaaa gctgaatcat tgaaaacgta 1500

 ccttgaaact ctctatctct ggacactcca gggtagagaa tgaagggtat 1550

 ggaagtagtc cggcttttga aacttaggta ttttatattt ttcccctcaa 1600

 gaactttttt ttaagagaca gatttgccat cctccttaat ttgcaggact 1650

 gccttggtgg ctttgtttgc tgggacaagg cccacaacct gtgcctctcc 1700

 tattgaccct tactttgaat tcaaagaatc tatttaagag tttaatatat 1750

 gaggctttct ttgattcctc ctcagttcta cctagtttca cagaggaaaa 1800

 aaatactctt tgaataaagt gaacagaggc tcatttgttt gtgcctcact 1850

 ttaca 1855

<210> 1056
<211> 377
<212> PRT
<213> Homo sapien

<400> 1056
 Met Arg Leu Ser Val Arg Arg Val Leu Leu Ala Ala Gly Cys Ala
   1               5                  10                  15

 Leu Val Leu Val Leu Ala Val Gln Leu Gly Gln Gln Val Leu Glu
                  20                  25                  30

 Cys Arg Ala Val Leu Ala Gly Leu Arg Ser Pro Arg Gly Ala Met
                  35                  40                  45

 Arg Pro Glu Gln Glu Glu Leu Val Met Val Gly Thr Asn His Val
                  50                  55                  60

 Glu Tyr Arg Tyr Gly Lys Ala Met Pro Leu Ile Phe Val Gly Gly
                  65                  70                  75

 Val Pro Arg Ser Gly Thr Thr Leu Met Arg Ala Met Leu Asp Ala
                  80                  85                  90

 His Pro Glu Val Arg Cys Gly Glu Glu Thr Arg Ile Ile Pro Arg
                  95                 100                 105

 Val Leu Ala Met Arg Gln Ala Trp Ser Lys Ser Gly Arg Glu Lys
                 110                 115                 120

 Leu Arg Leu Asp Glu Ala Gly Val Thr Asp Glu Val Leu Asp Ala
                 125                 130                 135

 Ala Met Gln Ala Phe Ile Leu Glu Val Ile Ala Lys His Gly Glu
                 140                 145                 150

 Pro Ala Arg Val Leu Cys Asn Lys Asp Pro Phe Thr Leu Lys Ser
                 155                 160                 165

 Ser Val Tyr Leu Ser Arg Leu Phe Pro Asn Ser Lys Phe Leu Leu
                 170                 175                 180

 Met Val Arg Asp Gly Arg Ala Ser Val His Ser Met Ile Thr Arg
                 185                 190                 195

 Lys Val Thr Ile Ala Gly Phe Asp Leu Ser Ser Tyr Arg Asp Cys
                 200                 205                 210

 Leu Thr Lys Trp Asn Lys Ala Ile Glu Val Met Tyr Ala Gln Cys
                 215                 220                 225

 Met Glu Val Gly Lys Glu Lys Cys Leu Pro Val Tyr Tyr Glu Gln
                 230                 235                 240

 Leu Val Leu His Pro Arg Arg Ser Leu Lys Leu Ile Leu Asp Phe
                 245                 250                 255

 Leu Gly Ile Ala Trp Ser Asp Ala Val Leu His His Glu Asp Leu
                 260                 265                 270

 Ile Gly Lys Pro Gly Gly Val Ser Leu Ser Lys Ile Glu Arg Ser
                 275                 280                 285

 Thr Asp Gln Val Ile Lys Pro Val Asn Leu Glu Ala Leu Ser Lys
                 290                 295                 300

 Trp Thr Gly His Ile Pro Gly Asp Val Val Arg Asp Met Ala Gln
                 305                 310                 315

 Ile Ala Pro Met Leu Ala Gln Leu Gly Tyr Asp Pro Tyr Ala Asn
                 320                 325                 330

 Pro Pro Asn Tyr Gly Asn Pro Asp Pro Phe Val Ile Asn Asn Thr
                 335                 340                 345

 Gln Arg Val Leu Lys Gly Asp Tyr Lys Thr Pro Ala Asn Leu Lys
                 350                 355                 360

 Gly Tyr Phe Gln Val Asn Gln Asn Ser Thr Ser Ser His Leu Gly
                 365                 370                 375

 Ser Ser


<210> 1057
<211> 2591
<212> DNA
<213> Homo sapien

<400> 1057
 gcggccgcct ccccctcccc ctccccctct ttcttctcct ccctcgtcgc 50

 cgccgccgcc gccgccgcct cagccttcgc ctcagcgccg cccgctcgcc 100

 gcgcgcggcg ggatggacga tcaatccagg atgctgcaga ctctggccgg 150

 ggtgaacctg gctggccact cggtgcaggg gggcatggcc ctgccgcctc 200

 ccccgcacgg ccacgaaggg gcggacggcg acggcaggaa gcaggacatc 250

 ggcgacatcc tccaccagat catgaccatc accgaccaga gcttggacga 300

 ggcgcaagca aagaaacatg ccctgaactg tcacagaatg aaaccagcgc 350

 tcttcagcgt cctgtgtgag atcaaagaga aaacaggtct cagcatcaga 400

 ggagcccagg aggaggaccc tcccgatccc cagctaatga gactggacaa 450

 tatgcttttg gcagaagggg tttcaggtcc tgagaaaggt gggggatcgg 500

 cggcagcagc tgcagccgcg gcagcctctg gaggttcttc agataactct 550

 attgaacact cagattacag agccaaattg acccagatca gacaaatcta 600

 tcacacagaa ctggagaaat atgaacaggc atgtaatgaa tttactacac 650

 atgtgatgaa ccttctccga gaacagagta gaacacgtcc catttctcca 700

 aaagagattg aaagaatggt gggcatcatc catcgaaaat ttagttccat 750

 tcagatgcag ctcaaacaaa gcacttgtga agcagttatg attttaagat 800

 caaggttcct tgatgccaga cggaaaaggc gtaacttcag taaacaggcc 850

 acagaaatct tgaatgaata tttttactca cacctcagca acccctaccc 900

 cagtgaagaa gccaaagagg agctggccaa gaaatgcagc atcacagtgt 950

 cacaggtatc caattggttt ggcaacaaac gaatcaggta caagaagaac 1000

 attggcaagt ttcaggaaga agccaacctc tatgctgcaa agacggccgt 1050

 gacagctgca cacgcagtag cagcagctgt gcagaacaac cagaccaatt 1100

 cgcccaccac accaaattcc ggttcttctg gttcttttaa cctcccaaat 1150

 tctggggaca tgttcatgaa catgcagagt ctgaatgggg attcttacca 1200

 agggtcccaa gtcggagcca atgtgcaatc acaggtggat accctccgtc 1250

 atgttatcaa tcagacggga ggctacagtg atggccttgg aggaaattca 1300

 ctgtacagtc cacataattt aaatgctaat ggaggctggc aggacgcaac 1350

 aactccatct tctgtgactt ctcctacaga aggcccagga agtgtgcact 1400

 cggatacctc taactaatct ctggccacac ttttcctgag ctacatgcct 1450

 tgataagtgc attcagagca ataggaggaa aaggaaagcg tttttgtagc 1500

 ccaccatcta cagctttact gtaaaacctt gtcttattcg agaacttggt 1550

 aaatctgttt ttaaggaatc ataatcattt gtatttatac ttaaaaacac 1600

 acaatgttaa aaaaaataaa gcactttatc caattaggcc aagatttaac 1650

 attgttgaca gtcctgtagc tattttatca taatttatta tcaatatttt 1700

 acattaatgg tttcacagtt gccaattact tggccttaag ggtaaaaagt 1750

 acaatataca ctaaacctca accgttaaag cagatgcaaa aattcacctc 1800

 acctaaattg aacttcttgc atatttccat tactgacttg gattgtcttt 1850

 ctttcatatc actaatggag ttggaataaa gagctgtttg cctatccctg 1900

 ttaatgatgg ttgtgtttaa gaatcttcct cgtcacgttt gtgttcagat 1950

 ctcttatgtt ataattagat cagagactgg tagcatcgtt tctctctctg 2000

 aaagcaccag tgcccagagt ctgctcggta ataaaattat ggatccagat 2050

 tgttctgaga gacgaagata cttgctgctg atagaggtga aaacgagatt 2100

 gatccgtctg gggttttacg gtgtgcactg ggtgctgcac agacttgtca 2150

 aggtttgcta cgtcctctgg gcatctgcaa aaggccctgc tctctggagt 2200

 gttgtatata gtgtagcaaa agagtattta tacatcccac caatcaaaac 2250

 acagctttat tacctcatgc gaactcatac aaaccaatag aatttcaaca 2300

 tgttctgtag cttagagtgc tcacttacta cctctgaaca atactcacgc 2350

 tgtagtttgt ctctttctta tctttttgca tcttgtaatt aactctttgt 2400

 ttcccttcat aaaatgtaat gtacattgta atcttttaaa agaaaaatca 2450

 gggttgcact tgcaactttt aaaaaaccga gtgtggaaac attgggtctt 2500

 aattcaacac aggatcggta aaactgttgt aaatactgag aaacattttg 2550

 aatgttcttc aatcttatta ctaatccatg caaaaaaaaa a 2591

<210> 1058
<211> 434
<212> PRT
<213> Homo sapien

<400> 1058
 Met Asp Asp Gln Ser Arg Met Leu Gln Thr Leu Ala Gly Val Asn
   1               5                  10                  15

 Leu Ala Gly His Ser Val Gln Gly Gly Met Ala Leu Pro Pro Pro
                  20                  25                  30

 Pro His Gly His Glu Gly Ala Asp Gly Asp Gly Arg Lys Gln Asp
                  35                  40                  45

 Ile Gly Asp Ile Leu His Gln Ile Met Thr Ile Thr Asp Gln Ser
                  50                  55                  60

 Leu Asp Glu Ala Gln Ala Lys Lys His Ala Leu Asn Cys His Arg
                  65                  70                  75

 Met Lys Pro Ala Leu Phe Ser Val Leu Cys Glu Ile Lys Glu Lys
                  80                  85                  90

 Thr Gly Leu Ser Ile Arg Gly Ala Gln Glu Glu Asp Pro Pro Asp
                  95                 100                 105

 Pro Gln Leu Met Arg Leu Asp Asn Met Leu Leu Ala Glu Gly Val
                 110                 115                 120

 Ser Gly Pro Glu Lys Gly Gly Gly Ser Ala Ala Ala Ala Ala Ala
                 125                 130                 135

 Ala Ala Ala Ser Gly Gly Ser Ser Asp Asn Ser Ile Glu His Ser
                 140                 145                 150

 Asp Tyr Arg Ala Lys Leu Thr Gln Ile Arg Gln Ile Tyr His Thr
                 155                 160                 165

 Glu Leu Glu Lys Tyr Glu Gln Ala Cys Asn Glu Phe Thr Thr His
                 170                 175                 180

 Val Met Asn Leu Leu Arg Glu Gln Ser Arg Thr Arg Pro Ile Ser
                 185                 190                 195

 Pro Lys Glu Ile Glu Arg Met Val Gly Ile Ile His Arg Lys Phe
                 200                 205                 210

 Ser Ser Ile Gln Met Gln Leu Lys Gln Ser Thr Cys Glu Ala Val
                 215                 220                 225

 Met Ile Leu Arg Ser Arg Phe Leu Asp Ala Arg Arg Lys Arg Arg
                 230                 235                 240

 Asn Phe Ser Lys Gln Ala Thr Glu Ile Leu Asn Glu Tyr Phe Tyr
                 245                 250                 255

 Ser His Leu Ser Asn Pro Tyr Pro Ser Glu Glu Ala Lys Glu Glu
                 260                 265                 270

 Leu Ala Lys Lys Cys Ser Ile Thr Val Ser Gln Val Ser Asn Trp
                 275                 280                 285

 Phe Gly Asn Lys Arg Ile Arg Tyr Lys Lys Asn Ile Gly Lys Phe
                 290                 295                 300

 Gln Glu Glu Ala Asn Leu Tyr Ala Ala Lys Thr Ala Val Thr Ala
                 305                 310                 315

 Ala His Ala Val Ala Ala Ala Val Gln Asn Asn Gln Thr Asn Ser
                 320                 325                 330

 Pro Thr Thr Pro Asn Ser Gly Ser Ser Gly Ser Phe Asn Leu Pro
                 335                 340                 345

 Asn Ser Gly Asp Met Phe Met Asn Met Gln Ser Leu Asn Gly Asp
                 350                 355                 360

 Ser Tyr Gln Gly Ser Gln Val Gly Ala Asn Val Gln Ser Gln Val
                 365                 370                 375

 Asp Thr Leu Arg His Val Ile Asn Gln Thr Gly Gly Tyr Ser Asp
                 380                 385                 390

 Gly Leu Gly Gly Asn Ser Leu Tyr Ser Pro His Asn Leu Asn Ala
                 395                 400                 405

 Asn Gly Gly Trp Gln Asp Ala Thr Thr Pro Ser Ser Val Thr Ser
                 410                 415                 420

 Pro Thr Glu Gly Pro Gly Ser Val His Ser Asp Thr Ser Asn
                 425                 430

<210> 1059
<211> 2253
<212> DNA
<213> Homo sapien

<400> 1059
 ggaagacttg ggtccttggg tcgcaggtgg gagccgacgg gtgggtagac 50

 cgtgggggat atctcagtgg cggacgagga cggcggggac aaggggcggc 100

 tggtcggagt ggcggagcgt caagtcccct gtcggttcct ccgtccctga 150

 gtgtccttgg cgctgccttg tgcccgccca gcgcctttgc atccgctcct 200

 gggcaccgag gcgccctgta ggatactgct tgttacttat tacagctaga 250

 ggcatcatgg accgatctaa agaaaactgc atttcaggac ctgttaaggc 300

 tacagctcca gttggaggtc caaaacgtgt tctcgtgact cagcaaattc 350

 cttgtcagaa tccattacct gtaaatagtg gccaggctca gcgggtcttg 400

 tgtccttcaa attcttccca gcgcgttcct ttgcaagcac aaaagcttgt 450

 ctccagtcac aagccggttc agaatcagaa gcagaagcaa ttgcaggcaa 500

 ccagtgtacc tcatcctgtc tccaggccac tgaataacac ccaaaagagc 550

 aagcagcccc tgccatcggc acctgaaaat aatcctgagg aggaactggc 600

 atcaaaacag aaaaatgaag aatcaaaaaa gaggcagtgg gctttggaag 650

 actttgaaat tggtcgccct ctgggtaaag gaaagtttgg taatgtttat 700

 ttggcaagag aaaagcaaag caagtttatt ctggctctta aagtgttatt 750

 taaagctcag ctggagaaag ccggagtgga gcatcagctc agaagagaag 800

 tagaaataca gtcccacctt cggcatccta atattcttag actgtatggt 850

 tatttccatg atgctaccag agtctaccta attctggaat atgcaccact 900

 tggaacagtt tatagagaac ttcagaaact ttcaaagttt gatgagcaga 950

 gaactgctac ttatataaca gaattggcaa atgccctgtc ttactgtcat 1000

 tcgaagagag ttattcatag agacattaag ccagagaact tacttcttgg 1050

 atcagctgga gagcttaaaa ttgcagattt tgggtggtca gtacatgctc 1100

 catcttccag gaggaccact ctctgtggca ccctggacta cctgccccct 1150

 gaaatgattg aaggtcggat gcatgatgag aaggtggatc tctggagcct 1200

 tggagttctt tgctatgaat ttttagttgg gaagcctcct tttgaggcaa 1250

 acacatacca agagacctac aaaagaatat cacgggttga attcacattc 1300

 cctgactttg taacagaggg agccagggac ctcatttcaa gactgttgaa 1350

 gcataatccc agccagaggc caatgctcag agaagtactt gaacacccct 1400

 ggatcacagc aaattcatca aaaccatcaa attgccaaaa caaagaatca 1450

 gctagcaaac agtcttagga atcgtgcagg gggagaaatc cttgagccag 1500

 ggctgccata taacctgaca ggaacatgct actgaagttt attttaccat 1550

 tgactgctgc cctcaatcta gaacgctaca caagaaatat ttgttttact 1600

 cagcaggtgt gccttaacct ccctattcag aaagctccac atcaataaac 1650

 atgacactct gaagtgaaag tagccacgag aattgtgcta cttatactgg 1700

 ttcataatct ggaggcaagg ttcgactgca gccgccccgt cagcctgtgc 1750

 taggcatggt gtcttcacag gaggcaaatc cagagcctgg ctgtggggaa 1800

 agtgaccact ctgccctgac cccgatcagt taaggagctg tgcaataacc 1850

 ttcctagtac ctgagtgagt gtgtaactta ttgggttggc gaagcctggt 1900

 aaagctgttg gaatgagtat gtgattcttt ttaagtatga aaataaagat 1950

 atatgtacag acttgtattt tttctctggt ggcattcctt taggaatgct 2000

 gtgtgtctgt ccggcacccc ggtaggcctg attgggtttc tagtcctcct 2050

 taaccactta tctcccatat gagagtgtga aaaataggaa cacgtgctct 2100

 acctccattt agggatttgc ttgggataca gaagaggcca tgtgtctcag 2150

 agctgttaag ggcttatttt tttaaaacat tggagtcata gcatgtgtgt 2200

 aaactttaaa tatgcaaata aataagtatc tatgtctaaa aaaaaaaaaa 2250

 aaa 2253

<210> 1060
<211> 403
<212> PRT
<213> Homo sapien

<400> 1060
 Met Asp Arg Ser Lys Glu Asn Cys Ile Ser Gly Pro Val Lys Ala
   1               5                  10                  15

 Thr Ala Pro Val Gly Gly Pro Lys Arg Val Leu Val Thr Gln Gln
                  20                  25                  30

 Ile Pro Cys Gln Asn Pro Leu Pro Val Asn Ser Gly Gln Ala Gln
                  35                  40                  45

 Arg Val Leu Cys Pro Ser Asn Ser Ser Gln Arg Val Pro Leu Gln
                  50                  55                  60

 Ala Gln Lys Leu Val Ser Ser His Lys Pro Val Gln Asn Gln Lys
                  65                  70                  75

 Gln Lys Gln Leu Gln Ala Thr Ser Val Pro His Pro Val Ser Arg
                  80                  85                  90

 Pro Leu Asn Asn Thr Gln Lys Ser Lys Gln Pro Leu Pro Ser Ala
                  95                 100                 105

 Pro Glu Asn Asn Pro Glu Glu Glu Leu Ala Ser Lys Gln Lys Asn
                 110                 115                 120

 Glu Glu Ser Lys Lys Arg Gln Trp Ala Leu Glu Asp Phe Glu Ile
                 125                 130                 135

 Gly Arg Pro Leu Gly Lys Gly Lys Phe Gly Asn Val Tyr Leu Ala
                 140                 145                 150

 Arg Glu Lys Gln Ser Lys Phe Ile Leu Ala Leu Lys Val Leu Phe
                 155                 160                 165

 Lys Ala Gln Leu Glu Lys Ala Gly Val Glu His Gln Leu Arg Arg
                 170                 175                 180

 Glu Val Glu Ile Gln Ser His Leu Arg His Pro Asn Ile Leu Arg
                 185                 190                 195

 Leu Tyr Gly Tyr Phe His Asp Ala Thr Arg Val Tyr Leu Ile Leu
                 200                 205                 210

 Glu Tyr Ala Pro Leu Gly Thr Val Tyr Arg Glu Leu Gln Lys Leu
                 215                 220                 225

 Ser Lys Phe Asp Glu Gln Arg Thr Ala Thr Tyr Ile Thr Glu Leu
                 230                 235                 240

 Ala Asn Ala Leu Ser Tyr Cys His Ser Lys Arg Val Ile His Arg
                 245                 250                 255

 Asp Ile Lys Pro Glu Asn Leu Leu Leu Gly Ser Ala Gly Glu Leu
                 260                 265                 270

 Lys Ile Ala Asp Phe Gly Trp Ser Val His Ala Pro Ser Ser Arg
                 275                 280                 285

 Arg Thr Thr Leu Cys Gly Thr Leu Asp Tyr Leu Pro Pro Glu Met
                 290                 295                 300

 Ile Glu Gly Arg Met His Asp Glu Lys Val Asp Leu Trp Ser Leu
                 305                 310                 315

 Gly Val Leu Cys Tyr Glu Phe Leu Val Gly Lys Pro Pro Phe Glu
                 320                 325                 330

 Ala Asn Thr Tyr Gln Glu Thr Tyr Lys Arg Ile Ser Arg Val Glu
                 335                 340                 345

 Phe Thr Phe Pro Asp Phe Val Thr Glu Gly Ala Arg Asp Leu Ile
                 350                 355                 360

 Ser Arg Leu Leu Lys His Asn Pro Ser Gln Arg Pro Met Leu Arg
                 365                 370                 375

 Glu Val Leu Glu His Pro Trp Ile Thr Ala Asn Ser Ser Lys Pro
                 380                 385                 390

 Ser Asn Cys Gln Asn Lys Glu Ser Ala Ser Lys Gln Ser
                 395                 400

<210> 1061
<211> 696
<212> DNA
<213> Homo sapien

<400> 1061
 ttcccccccc cccccccccc ccccgcccga gcacaggaca cagctgggtt 50

 ctgaagcttc tgagttctgc agcctcacct ctgagaaaac ctcttttcca 100

 ccaataccat gaagctctgc gtgactgtcc tgtctctcct catgctagta 150

 gctgccttct gctctccagc gctctcagca ccaatgggct cagaccctcc 200

 caccgcctgc tgcttttctt acaccgcgag gaagcttcct cgcaactttg 250

 tggtagatta ctatgagacc agcagcctct gctcccagcc agctgtggta 300

 ttccaaacca aaagaagcaa gcaagtctgt gctgatccca gtgaatcctg 350

 ggtccaggag tacgtgtatg acctggaact gaactgagct gctcagagac 400

 aggaagtctt cagggaaggt cacctgagcc cggatgcttc tccatgagac 450

 acatctcctc catactcagg actcctctcc gcagttcctg tcccttctct 500

 taatttaatc ttttttatgt gccgtgttat tgtattaggt gtcatttcca 550

 ttatttatat tagtttagcc aaaggataag tgtcctatgg ggatggtcca 600

 ctgtcactgt ttctctgctg ttgcaaatac atggataaca catttgattc 650

 tgtgtgtttt ccataataaa actttaaaat aaaatgcaga cagtta 696

<210> 1062
<211> 92
<212> PRT
<213> Homo sapien

<400> 1062
 Met Lys Leu Cys Val Thr Val Leu Ser Leu Leu Met Leu Val Ala
   1               5                  10                  15

 Ala Phe Cys Ser Pro Ala Leu Ser Ala Pro Met Gly Ser Asp Pro
                  20                  25                  30

 Pro Thr Ala Cys Cys Phe Ser Tyr Thr Ala Arg Lys Leu Pro Arg
                  35                  40                  45

 Asn Phe Val Val Asp Tyr Tyr Glu Thr Ser Ser Leu Cys Ser Gln
                  50                  55                  60

 Pro Ala Val Val Phe Gln Thr Lys Arg Ser Lys Gln Val Cys Ala
                  65                  70                  75

 Asp Pro Ser Glu Ser Trp Val Gln Glu Tyr Val Tyr Asp Leu Glu
                  80                  85                  90

 Leu Asn


<210> 1063
<211> 1099
<212> DNA
<213> Homo sapien

<400> 1063
 tcctgcgttg ctgggaagtt ctggaaggaa gcatgtgctc cagaggttgg 50

 gattcgtgtc tggctctgga attgctactg ctgcctctgt cactcctggt 100

 gaccagcatt caaggtcact tggtacatat gaccgtggtc tccggcagca 150

 acgtgactct gaacatctct gagagcctgc ctgagaacta caaacaacta 200

 acctggtttt atactttcga ccagaagatt gtagaatggg attccagaaa 250

 atctaagtac tttgaatcca aatttaaagg cagggtcaga cttgatcctc 300

 agagtggcgc actgtacatc tctaaggtcc agaaagagga caacagcacc 350

 tacatcatga gggtgttgaa aaagactggg aatgagcaag aatggaagat 400

 caagctgcaa gtgcttgacc ctgtacccaa gcctgtcatc aaaattgaga 450

 agatagaaga catggatgac aactgttatt tgaaactgtc atgtgtgata 500

 cctggcgagt ctgtaaacta cacctggtat ggggacaaaa ggcccttccc 550

 aaaggagctc cagaacagtg tgcttgaaac cacccttatg ccacataatt 600

 actccaggtg ttatacttgc caagtcagca attctgtgag cagcaagaat 650

 ggcacggtct gcctcagtcc accctgtacc ctggcccggt cctttggagt 700

 agaatggatt gcaagttggc tagtggtcac ggtgcccacc attcttggcc 750

 tgttacttac ctgagatgag ctcttttaac tcaagcgaaa cttcaaggcc 800

 agaagatctt gcctgttggt gatcatgctc ctcaccagga cagagactgt 850

 ataggctgac cagaagcatg ctgctgaatt atcaacgagg attttcaagt 900

 taacttttaa atactggtta ttatttaatt ttatatccct ttgttgtttt 950

 ctagtacaca gagatataga gatacacatg cttttttccc acccaaaatt 1000

 gtgacaacat tatgtgaatg ttttattatt ttttaaaata aacatttgat 1050

 ataattatca attaactgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1099

<210> 1064
<211> 243
<212> PRT
<213> Homo sapien

<400> 1064
 Met Cys Ser Arg Gly Trp Asp Ser Cys Leu Ala Leu Glu Leu Leu
   1               5                  10                  15

 Leu Leu Pro Leu Ser Leu Leu Val Thr Ser Ile Gln Gly His Leu
                  20                  25                  30

 Val His Met Thr Val Val Ser Gly Ser Asn Val Thr Leu Asn Ile
                  35                  40                  45

 Ser Glu Ser Leu Pro Glu Asn Tyr Lys Gln Leu Thr Trp Phe Tyr
                  50                  55                  60

 Thr Phe Asp Gln Lys Ile Val Glu Trp Asp Ser Arg Lys Ser Lys
                  65                  70                  75

 Tyr Phe Glu Ser Lys Phe Lys Gly Arg Val Arg Leu Asp Pro Gln
                  80                  85                  90

 Ser Gly Ala Leu Tyr Ile Ser Lys Val Gln Lys Glu Asp Asn Ser
                  95                 100                 105

 Thr Tyr Ile Met Arg Val Leu Lys Lys Thr Gly Asn Glu Gln Glu
                 110                 115                 120

 Trp Lys Ile Lys Leu Gln Val Leu Asp Pro Val Pro Lys Pro Val
                 125                 130                 135

 Ile Lys Ile Glu Lys Ile Glu Asp Met Asp Asp Asn Cys Tyr Leu
                 140                 145                 150

 Lys Leu Ser Cys Val Ile Pro Gly Glu Ser Val Asn Tyr Thr Trp
                 155                 160                 165

 Tyr Gly Asp Lys Arg Pro Phe Pro Lys Glu Leu Gln Asn Ser Val
                 170                 175                 180

 Leu Glu Thr Thr Leu Met Pro His Asn Tyr Ser Arg Cys Tyr Thr
                 185                 190                 195

 Cys Gln Val Ser Asn Ser Val Ser Ser Lys Asn Gly Thr Val Cys
                 200                 205                 210

 Leu Ser Pro Pro Cys Thr Leu Ala Arg Ser Phe Gly Val Glu Trp
                 215                 220                 225

 Ile Ala Ser Trp Leu Val Val Thr Val Pro Thr Ile Leu Gly Leu
                 230                 235                 240

 Leu Leu Thr


<210> 1065
<211> 1932
<212> DNA
<213> Homo sapien

<400> 1065
 ggcacgaggc ctcgtgccgc cgggctcttg gtacctcagc gcgagcgcca 50

 ggcgtccggc cgccgtggct atgttcgtgt ccgatttccg caaagagttc 100

 tacgaggtgg tccagagcca gagggtcctt ctcttcgtgg cctcggacgt 150

 ggatgctctg tgtgcgtgca agatccttca ggccttgttc cagtgtgacc 200

 acgtgcaata tacgctggtt ccagtttctg ggtggcaaga acttgaaact 250

 gcatttcttg agcataaaga acagtttcat tattttattc tcataaactg 300

 tggagctaat gtagacctat tggatattct tcaacctgat gaagacacta 350

 tattctttgt gtgtgacacc cataggccag tcaatgtcgt caatgtatac 400

 aacgataccc agatcaaatt actcattaaa caagatgatg accttgaagt 450

 tcccgcctat gaagacatct tcagggatga agaggaggat gaagagcatt 500

 caggaaatga cagtgatggg tcagagcctt ctgagaagcg cacacggtta 550

 gaagaggaga tagtggagca aaccatgcgg aggaggcagc ggcgagagtg 600

 ggaggcccgg agaagagaca tcctctttga ctacgagcag tatgaatatc 650

 atgggacatc gtcagccatg gtgatgtttg agctggcttg gatgctgtcc 700

 aaggacctga atgacatgct gtggtgggcc atcgttggac taacagacca 750

 gtgggtgcaa gacaagatca ctcaaatgaa atacgtgact gatgttggtg 800

 tcctgcagcg ccacgtttcc cgccacaacc accggaacga ggatgaggag 850

 aacacactct ccgtggactg cacacggatc tcctttgagt atgacctccg 900

 cctggtgctc taccagcact ggtccctcca tgacagcctg tgcaacacca 950

 gctataccgc agccaggttc aagctgtggt ctgtgcatgg acagaagcgg 1000

 ctccaggagt tccttgcaga catgggtctt cccctgaagc aggtgaagca 1050

 gaagttccag gccatggaca tctccttgaa ggagaatttg cgggaaatga 1100

 ttgaagagtc tgcaaataaa tttgggatga aggacatgcg cgtgcagact 1150

 ttcagcattc attttgggtt caagcacaag tttctggcca gcgacgtggt 1200

 ctttgccacc atgtctttga tggagagccc cgagaaggat ggctcaggga 1250

 cagatcactt catccaggct ctggacagcc tctccaggag taacctggac 1300

 aagctgtacc atggcctgga actcgccaag aagcagctgc gagccaccca 1350

 gcagaccatt gccagctgcc tttgcaccaa cctcgtcatc tcccaggggc 1400

 ctttcctgta ctgctctctc atggagggca ctccagatgt catgctgttc 1450

 tctaggccgg catccctaag cctgctcagc aaacacctgc tcaagtcctt 1500

 tgtgtgttcg acaaagaacc ggcgctgcaa actgctgccc ctggtgatgg 1550

 ctgcccccct gagcatggag catggcacag tgaccgtggt gggcatcccc 1600

 ccagagaccg acagctcgga caggaagaac ttttttggga gggcgtttga 1650

 gaaggcagcg gaaagcacca gctcccggat gctgcacaac cattttgacc 1700

 tctcagtaat tgagctgaaa gctgaggatc ggagcaagtt tctggacgca 1750

 cttatttccc tcctgtccta ggaatttgat tcttccagaa tgaccttctt 1800

 atttatgtaa ctggctttca tttagattgt aagttatgga catgatttga 1850

 gatgtagaag ccatttttta ttaaataaaa tgcttatttt aggctccgtc 1900

 cccaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1932

<210> 1066
<211> 566
<212> PRT
<213> Homo sapien

<400> 1066
 Met Phe Val Ser Asp Phe Arg Lys Glu Phe Tyr Glu Val Val Gln
   1               5                  10                  15

 Ser Gln Arg Val Leu Leu Phe Val Ala Ser Asp Val Asp Ala Leu
                  20                  25                  30

 Cys Ala Cys Lys Ile Leu Gln Ala Leu Phe Gln Cys Asp His Val
                  35                  40                  45

 Gln Tyr Thr Leu Val Pro Val Ser Gly Trp Gln Glu Leu Glu Thr
                  50                  55                  60

 Ala Phe Leu Glu His Lys Glu Gln Phe His Tyr Phe Ile Leu Ile
                  65                  70                  75

 Asn Cys Gly Ala Asn Val Asp Leu Leu Asp Ile Leu Gln Pro Asp
                  80                  85                  90

 Glu Asp Thr Ile Phe Phe Val Cys Asp Thr His Arg Pro Val Asn
                  95                 100                 105

 Val Val Asn Val Tyr Asn Asp Thr Gln Ile Lys Leu Leu Ile Lys
                 110                 115                 120

 Gln Asp Asp Asp Leu Glu Val Pro Ala Tyr Glu Asp Ile Phe Arg
                 125                 130                 135

 Asp Glu Glu Glu Asp Glu Glu His Ser Gly Asn Asp Ser Asp Gly
                 140                 145                 150

 Ser Glu Pro Ser Glu Lys Arg Thr Arg Leu Glu Glu Glu Ile Val
                 155                 160                 165

 Glu Gln Thr Met Arg Arg Arg Gln Arg Arg Glu Trp Glu Ala Arg
                 170                 175                 180

 Arg Arg Asp Ile Leu Phe Asp Tyr Glu Gln Tyr Glu Tyr His Gly
                 185                 190                 195

 Thr Ser Ser Ala Met Val Met Phe Glu Leu Ala Trp Met Leu Ser
                 200                 205                 210

 Lys Asp Leu Asn Asp Met Leu Trp Trp Ala Ile Val Gly Leu Thr
                 215                 220                 225

 Asp Gln Trp Val Gln Asp Lys Ile Thr Gln Met Lys Tyr Val Thr
                 230                 235                 240

 Asp Val Gly Val Leu Gln Arg His Val Ser Arg His Asn His Arg
                 245                 250                 255

 Asn Glu Asp Glu Glu Asn Thr Leu Ser Val Asp Cys Thr Arg Ile
                 260                 265                 270

 Ser Phe Glu Tyr Asp Leu Arg Leu Val Leu Tyr Gln His Trp Ser
                 275                 280                 285

 Leu His Asp Ser Leu Cys Asn Thr Ser Tyr Thr Ala Ala Arg Phe
                 290                 295                 300

 Lys Leu Trp Ser Val His Gly Gln Lys Arg Leu Gln Glu Phe Leu
                 305                 310                 315

 Ala Asp Met Gly Leu Pro Leu Lys Gln Val Lys Gln Lys Phe Gln
                 320                 325                 330

 Ala Met Asp Ile Ser Leu Lys Glu Asn Leu Arg Glu Met Ile Glu
                 335                 340                 345

 Glu Ser Ala Asn Lys Phe Gly Met Lys Asp Met Arg Val Gln Thr
                 350                 355                 360

 Phe Ser Ile His Phe Gly Phe Lys His Lys Phe Leu Ala Ser Asp
                 365                 370                 375

 Val Val Phe Ala Thr Met Ser Leu Met Glu Ser Pro Glu Lys Asp
                 380                 385                 390

 Gly Ser Gly Thr Asp His Phe Ile Gln Ala Leu Asp Ser Leu Ser
                 395                 400                 405

 Arg Ser Asn Leu Asp Lys Leu Tyr His Gly Leu Glu Leu Ala Lys
                 410                 415                 420

 Lys Gln Leu Arg Ala Thr Gln Gln Thr Ile Ala Ser Cys Leu Cys
                 425                 430                 435

 Thr Asn Leu Val Ile Ser Gln Gly Pro Phe Leu Tyr Cys Ser Leu
                 440                 445                 450

 Met Glu Gly Thr Pro Asp Val Met Leu Phe Ser Arg Pro Ala Ser
                 455                 460                 465

 Leu Ser Leu Leu Ser Lys His Leu Leu Lys Ser Phe Val Cys Ser
                 470                 475                 480

 Thr Lys Asn Arg Arg Cys Lys Leu Leu Pro Leu Val Met Ala Ala
                 485                 490                 495

 Pro Leu Ser Met Glu His Gly Thr Val Thr Val Val Gly Ile Pro
                 500                 505                 510

 Pro Glu Thr Asp Ser Ser Asp Arg Lys Asn Phe Phe Gly Arg Ala
                 515                 520                 525

 Phe Glu Lys Ala Ala Glu Ser Thr Ser Ser Arg Met Leu His Asn
                 530                 535                 540

 His Phe Asp Leu Ser Val Ile Glu Leu Lys Ala Glu Asp Arg Ser
                 545                 550                 555

 Lys Phe Leu Asp Ala Leu Ile Ser Leu Leu Ser
                 560                 565

<210> 1067
<211> 1479
<212> DNA
<213> Homo sapien

<400> 1067
 cgagctgcca tgagcctctg ggtggacaag tatcggccct gctccttggg 50

 acggctggac tatcacaagg agcaggcggc ccagctgcgg aacctggtgc 100

 agtgtggtga ctttcctcat ctgttagtgt acggaccatc aggtgctgga 150

 aaaaagacaa gaattatgtg tattttacgt gaactttatg gtgttggagt 200

 ggaaaaattg agaattgaac atcagaccat cacaactcca tctaaaaaaa 250

 aaattgaaat tagcaccatt gcaagtaact accaccttga agttaatcct 300

 agtgatgctg gaaatagtga ccgagtagtc attcaggaga tgttgaaaac 350

 agtggcacaa tcacaacaac ttgaaacaaa ctctcaaagg gattttaaag 400

 tggtattatt gacagaagtt gacaaactca ccaaagatgc tcagcatgcc 450

 ttgcgaagaa ccatggaaaa atatatgtct acctgcagat tgatcttgtg 500

 ctgcaattct acatctaaag tgatcccacc tattcgtagt aggtgcttgg 550

 cggttcgtgt gcctgctccc agcattgaag atatttgcca cgtgttatct 600

 actgtgtgta agaaggaagg tctgaatctt ccttcacaac tggctcatag 650

 acttgcagag aagtcttgta gaaatctcag aaaagccctg cttatgtgtg 700

 aagcctgcag agtgcaacaa tatcctttta ctgcagatca agaaatccct 750

 gagacagatt gggaggtgta tctgagggag actgcaaatg ctattgtcag 800

 tcagcaaact ccacaaaggc tccttgaagt tcgtggaagg ctgtatgagc 850

 ttctaactca ttgtattcct cctgagataa taatgaaggg ccttctctca 900

 gaactgttac ataattgtga tggacaactg aaaggggagg tggcacaaat 950

 ggcagcttac tatgagcatc gtctacagct gggtagcaaa gccatttatc 1000

 acttggaagc gtttgtggcc aaattcatgg cactttataa gaagttcatg 1050

 gaggatggat tggaaggcat gatgttctga cttctgtcag ttattcttgc 1100

 aaagatttct cagtatcagt atttacatac agcttatatt aaaagagctg 1150

 tgggtaaatt aactgaactt aatcatgtcg tatttgggtt tttttggtaa 1200

 taacttctct gtgaactatt aatcatcctc tgagttaaat aattgctcct 1250

 atactattga agtatgtagt tttgtacata acttagagac tttagagtct 1300

 aagaaaatga tcttaattta ctttaagcat tggttattca agtattcatt 1350

 gttgatcctc ctattctctt ccgtctaatc tctcacctgc taaaggagat 1400

 ttacacatta gaaagcaaag attattttca tttatccaga tgaccatttt 1450

 ctgccacagg taacatgatt gtttgacgg 1479

<210> 1068
<211> 356
<212> PRT
<213> Homo sapien

<400> 1068
 Met Ser Leu Trp Val Asp Lys Tyr Arg Pro Cys Ser Leu Gly Arg
   1               5                  10                  15

 Leu Asp Tyr His Lys Glu Gln Ala Ala Gln Leu Arg Asn Leu Val
                  20                  25                  30

 Gln Cys Gly Asp Phe Pro His Leu Leu Val Tyr Gly Pro Ser Gly
                  35                  40                  45

 Ala Gly Lys Lys Thr Arg Ile Met Cys Ile Leu Arg Glu Leu Tyr
                  50                  55                  60

 Gly Val Gly Val Glu Lys Leu Arg Ile Glu His Gln Thr Ile Thr
                  65                  70                  75

 Thr Pro Ser Lys Lys Lys Ile Glu Ile Ser Thr Ile Ala Ser Asn
                  80                  85                  90

 Tyr His Leu Glu Val Asn Pro Ser Asp Ala Gly Asn Ser Asp Arg
                  95                 100                 105

 Val Val Ile Gln Glu Met Leu Lys Thr Val Ala Gln Ser Gln Gln
                 110                 115                 120

 Leu Glu Thr Asn Ser Gln Arg Asp Phe Lys Val Val Leu Leu Thr
                 125                 130                 135

 Glu Val Asp Lys Leu Thr Lys Asp Ala Gln His Ala Leu Arg Arg
                 140                 145                 150

 Thr Met Glu Lys Tyr Met Ser Thr Cys Arg Leu Ile Leu Cys Cys
                 155                 160                 165

 Asn Ser Thr Ser Lys Val Ile Pro Pro Ile Arg Ser Arg Cys Leu
                 170                 175                 180

 Ala Val Arg Val Pro Ala Pro Ser Ile Glu Asp Ile Cys His Val
                 185                 190                 195

 Leu Ser Thr Val Cys Lys Lys Glu Gly Leu Asn Leu Pro Ser Gln
                 200                 205                 210

 Leu Ala His Arg Leu Ala Glu Lys Ser Cys Arg Asn Leu Arg Lys
                 215                 220                 225

 Ala Leu Leu Met Cys Glu Ala Cys Arg Val Gln Gln Tyr Pro Phe
                 230                 235                 240

 Thr Ala Asp Gln Glu Ile Pro Glu Thr Asp Trp Glu Val Tyr Leu
                 245                 250                 255

 Arg Glu Thr Ala Asn Ala Ile Val Ser Gln Gln Thr Pro Gln Arg
                 260                 265                 270

 Leu Leu Glu Val Arg Gly Arg Leu Tyr Glu Leu Leu Thr His Cys
                 275                 280                 285

 Ile Pro Pro Glu Ile Ile Met Lys Gly Leu Leu Ser Glu Leu Leu
                 290                 295                 300

 His Asn Cys Asp Gly Gln Leu Lys Gly Glu Val Ala Gln Met Ala
                 305                 310                 315

 Ala Tyr Tyr Glu His Arg Leu Gln Leu Gly Ser Lys Ala Ile Tyr
                 320                 325                 330

 His Leu Glu Ala Phe Val Ala Lys Phe Met Ala Leu Tyr Lys Lys
                 335                 340                 345

 Phe Met Glu Asp Gly Leu Glu Gly Met Met Phe
                 350                 355

<210> 1069
<211> 3025
<212> DNA
<213> Homo sapien

<400> 1069
 gcacgagcag gcagttcaga ttaaagaagc taattgatca agaaatcaag 50

 tctcaggagg agaaggagca agaaaaggag aaaagggtca ccaccctgaa 100

 agaggagctg accaagctga agtcttttgc tttgatggtg gtggatgaac 150

 agcaaaggct gacggcacag ctcacccttc aaagacagaa aatccaagag 200

 ctgaccacaa atgcaaagga aacacatacc aaactagccc ttgctgaagc 250

 cagagttcag gaggaagagc agaaggcaac cagactagag aaggaactgc 300

 aaacgcagac cacaaagttt caccaagacc aagacacaat tatggcgaag 350

 ctcaccaatg aggacagtca aaatcgccag cttcaacaaa agctggcagc 400

 actcagccgg cagattgatg agttagaaga gacaaacagg tctttacgaa 450

 aagcagaaga ggagctgcaa gatataaaag aaaaaatcag taagggagaa 500

 tatggaaacg ctggtatcat ggctgaagtg gaagagctca taaaaatgga 550

 ggagcagtgc agagatctca ataagaggct tgaaagggag acgttacaga 600

 gtaaagactt taaactagag gttgaaaaac tcagtaaaag aattatggct 650

 ctggaaaagt tagaagacgc tttcaacaaa agcaaacaag aatgctactc 700

 tctgaaatgc aatttagaaa aagaaaggat gaccacaaag cagttgtctc 750

 aagaactgga gagtttaaaa gtaaggatca aagagctaga agccattgaa 800

 agtcggctag aaaagacaga attcactcta aaagaggatt taactaaact 850

 gaaaacatta actgtgatgt ttgtagatga acggaaaaca atgagtgaaa 900

 aattaaagaa aactgaagat aaattacaag ctgcttcttc tcagcttcaa 950

 gtggagcaaa ataaagtaac aacagttact gagaagttaa ttgaggaaac 1000

 taaaagggcg ctcaagtcca aaaccgatgt agaagaaaag atgtacagcg 1050

 taaccaagga gagagatgat ttaaaaaaca aattgaaagc ggaagaagag 1100

 aaaggaaatg atctcctgtc aagagttaat atgttgaaaa ataggcttca 1150

 atcattggaa gcaattgaga aagatttcct aaaaaacaaa ttaaatcaag 1200

 actctgggaa atccacaaca gcattacacc aagaaaacaa taagattaag 1250

 gagctctctc aagaagtgga aagactgaaa ctgaagctaa aggacatgaa 1300

 agccattgag gatgacctca tgaaaacaga agatgaatat gagactctag 1350

 aacgaaggta tgctaatgaa cgagacaaag ctcaattttt atctaaagag 1400

 ctagaacatg ttaaaatgga acttgctaag tacaagttag cagaaaagac 1450

 agagaccagc catgaacaat ggcttttcaa aaggcttcaa gaagaagaag 1500

 ctaagtcagg gcacctctca agagaagtgg atgcattaaa agagaaaatt 1550

 catgaataca tggcaactga agacctaata tgtcacctcc agggagatca 1600

 ctcagtctgc aaaaaaaaac taaatcaaca agaaaacagg aacagagatt 1650

 taggaagaga gattgaaaac ctcactaagg agttagagag gtaccggcat 1700

 ttcagtaaga gcctcaggcc tagtctcaat ggaagaagaa tttccgatcc 1750

 tcaagtattt tctaaagaag ttcagacaga agcagtagac aatgaaccac 1800

 ctgattacaa gagcctcatt cctctggaac gtgcagtcat caatggtcag 1850

 ttatatgagg agagtgagaa tcaagacgag gaccctaatg atgagggatc 1900

 tgtgctgtcc ttcaaatgca gccagtctac tccatgtcct gttaacagaa 1950

 agctatggat tccctggatg aaatccaagg agggccatct tcagaatgga 2000

 aaaatgcaaa ctaaacccaa tgccaacttt gtgcaacctg gagatctagt 2050

 cctaagccac acacctgggc agccacttca tataaaggtt actccagacc 2100

 atgtacaaaa cacagccact cttgaaatca caagtccaac cacagagagt 2150

 cctcactctt acacgagtac tgcagtgata ccgaactgtg gcacgccaaa 2200

 gcaaaggata accatcctcc aaaacgcctc cataacacca gtaaagtcca 2250

 aaacctctac cgaagacctc atgaatttag aacaaggcat gtccccaatt 2300

 accatggcaa cctttgccag agcacagacc ccagagtctt gtggttctct 2350

 aactccagaa aggacaatgt ccctattcag gttttggctg tgactggttc 2400

 agctagctct cctgagcagg gacgctcccc agaaccaaca gaaatcagtg 2450

 ccaagcatgc gatattcaga gtctccccag accggcagtc atcatggcag 2500

 tttcagcgtt caaacagcaa tagctcaagt gtgataacta ctgaggataa 2550

 taaaatccac attcacttag gaagtcctta catgcaagct gtagccagcc 2600

 cttcagcacc actgcaggat aaccgaactc aaggcttaat taacggggca 2650

 ctaaacaaaa caaccaataa agtcaccagc agtattacta tcacaccaac 2700

 agccacacct cttcctcgac aatcacaaat tacagtaagt aatatatata 2750

 actgaccacg ctcaccctca tccagtccat actgatattt ttgcaaggaa 2800

 ctcaatcctt ttttaatcat ccctccatat cccccaagac tgactgaact 2850

 cgtactttgg gaaggtttgt gcatgaacta tacaagagta tctgaaacta 2900

 actgttgcct gcatagtcat atcgagtgtg cacttactgt atatcttttc 2950

 atttacatac ttgtatggaa aatatttagt ctgcacttgt ataaatacat 3000

 ctttatgtat ttgaaaaaaa aaaaa 3025

<210> 1070
<211> 752
<212> PRT
<213> Homo sapien

<400> 1070
 Met Val Val Asp Glu Gln Gln Arg Leu Thr Ala Gln Leu Thr Leu
   1               5                  10                  15

 Gln Arg Gln Lys Ile Gln Glu Leu Thr Thr Asn Ala Lys Glu Thr
                  20                  25                  30

 His Thr Lys Leu Ala Leu Ala Glu Ala Arg Val Gln Glu Glu Glu
                  35                  40                  45

 Gln Lys Ala Thr Arg Leu Glu Lys Glu Leu Gln Thr Gln Thr Thr
                  50                  55                  60

 Lys Phe His Gln Asp Gln Asp Thr Ile Met Ala Lys Leu Thr Asn
                  65                  70                  75

 Glu Asp Ser Gln Asn Arg Gln Leu Gln Gln Lys Leu Ala Ala Leu
                  80                  85                  90

 Ser Arg Gln Ile Asp Glu Leu Glu Glu Thr Asn Arg Ser Leu Arg
                  95                 100                 105

 Lys Ala Glu Glu Glu Leu Gln Asp Ile Lys Glu Lys Ile Ser Lys
                 110                 115                 120

 Gly Glu Tyr Gly Asn Ala Gly Ile Met Ala Glu Val Glu Glu Leu
                 125                 130                 135

 Ile Lys Met Glu Glu Gln Cys Arg Asp Leu Asn Lys Arg Leu Glu
                 140                 145                 150

 Arg Glu Thr Leu Gln Ser Lys Asp Phe Lys Leu Glu Val Glu Lys
                 155                 160                 165

 Leu Ser Lys Arg Ile Met Ala Leu Glu Lys Leu Glu Asp Ala Phe
                 170                 175                 180

 Asn Lys Ser Lys Gln Glu Cys Tyr Ser Leu Lys Cys Asn Leu Glu
                 185                 190                 195

 Lys Glu Arg Met Thr Thr Lys Gln Leu Ser Gln Glu Leu Glu Ser
                 200                 205                 210

 Leu Lys Val Arg Ile Lys Glu Leu Glu Ala Ile Glu Ser Arg Leu
                 215                 220                 225

 Glu Lys Thr Glu Phe Thr Leu Lys Glu Asp Leu Thr Lys Leu Lys
                 230                 235                 240

 Thr Leu Thr Val Met Phe Val Asp Glu Arg Lys Thr Met Ser Glu
                 245                 250                 255

 Lys Leu Lys Lys Thr Glu Asp Lys Leu Gln Ala Ala Ser Ser Gln
                 260                 265                 270

 Leu Gln Val Glu Gln Asn Lys Val Thr Thr Val Thr Glu Lys Leu
                 275                 280                 285

 Ile Glu Glu Thr Lys Arg Ala Leu Lys Ser Lys Thr Asp Val Glu
                 290                 295                 300

 Glu Lys Met Tyr Ser Val Thr Lys Glu Arg Asp Asp Leu Lys Asn
                 305                 310                 315

 Lys Leu Lys Ala Glu Glu Glu Lys Gly Asn Asp Leu Leu Ser Arg
                 320                 325                 330

 Val Asn Met Leu Lys Asn Arg Leu Gln Ser Leu Glu Ala Ile Glu
                 335                 340                 345

 Lys Asp Phe Leu Lys Asn Lys Leu Asn Gln Asp Ser Gly Lys Ser
                 350                 355                 360

 Thr Thr Ala Leu His Gln Glu Asn Asn Lys Ile Lys Glu Leu Ser
                 365                 370                 375

 Gln Glu Val Glu Arg Leu Lys Leu Lys Leu Lys Asp Met Lys Ala
                 380                 385                 390

 Ile Glu Asp Asp Leu Met Lys Thr Glu Asp Glu Tyr Glu Thr Leu
                 395                 400                 405

 Glu Arg Arg Tyr Ala Asn Glu Arg Asp Lys Ala Gln Phe Leu Ser
                 410                 415                 420

 Lys Glu Leu Glu His Val Lys Met Glu Leu Ala Lys Tyr Lys Leu
                 425                 430                 435

 Ala Glu Lys Thr Glu Thr Ser His Glu Gln Trp Leu Phe Lys Arg
                 440                 445                 450

 Leu Gln Glu Glu Glu Ala Lys Ser Gly His Leu Ser Arg Glu Val
                 455                 460                 465

 Asp Ala Leu Lys Glu Lys Ile His Glu Tyr Met Ala Thr Glu Asp
                 470                 475                 480

 Leu Ile Cys His Leu Gln Gly Asp His Ser Val Cys Lys Lys Lys
                 485                 490                 495

 Leu Asn Gln Gln Glu Asn Arg Asn Arg Asp Leu Gly Arg Glu Ile
                 500                 505                 510

 Glu Asn Leu Thr Lys Glu Leu Glu Arg Tyr Arg His Phe Ser Lys
                 515                 520                 525

 Ser Leu Arg Pro Ser Leu Asn Gly Arg Arg Ile Ser Asp Pro Gln
                 530                 535                 540

 Val Phe Ser Lys Glu Val Gln Thr Glu Ala Val Asp Asn Glu Pro
                 545                 550                 555

 Pro Asp Tyr Lys Ser Leu Ile Pro Leu Glu Arg Ala Val Ile Asn
                 560                 565                 570

 Gly Gln Leu Tyr Glu Glu Ser Glu Asn Gln Asp Glu Asp Pro Asn
                 575                 580                 585

 Asp Glu Gly Ser Val Leu Ser Phe Lys Cys Ser Gln Ser Thr Pro
                 590                 595                 600

 Cys Pro Val Asn Arg Lys Leu Trp Ile Pro Trp Met Lys Ser Lys
                 605                 610                 615

 Glu Gly His Leu Gln Asn Gly Lys Met Gln Thr Lys Pro Asn Ala
                 620                 625                 630

 Asn Phe Val Gln Pro Gly Asp Leu Val Leu Ser His Thr Pro Gly
                 635                 640                 645

 Gln Pro Leu His Ile Lys Val Thr Pro Asp His Val Gln Asn Thr
                 650                 655                 660

 Ala Thr Leu Glu Ile Thr Ser Pro Thr Thr Glu Ser Pro His Ser
                 665                 670                 675

 Tyr Thr Ser Thr Ala Val Ile Pro Asn Cys Gly Thr Pro Lys Gln
                 680                 685                 690

 Arg Ile Thr Ile Leu Gln Asn Ala Ser Ile Thr Pro Val Lys Ser
                 695                 700                 705

 Lys Thr Ser Thr Glu Asp Leu Met Asn Leu Glu Gln Gly Met Ser
                 710                 715                 720

 Pro Ile Thr Met Ala Thr Phe Ala Arg Ala Gln Thr Pro Glu Ser
                 725                 730                 735

 Cys Gly Ser Leu Thr Pro Glu Arg Thr Met Ser Leu Phe Arg Phe
                 740                 745                 750

 Trp Leu


<210> 1071
<211> 2143
<212> DNA
<213> Homo sapien

<400> 1071
 gaagccaaca agaatttgag aactgtaaat accaagcctt gaaagggacc 50

 atggtgcggc ctgtgagaca taagaaacca gtcaattact cacagtttga 100

 ccactctgac agtgatgatg attttgtttc tgcaactgta cctttaaaca 150

 agaaatccag aacagcacca aaggagttaa aacaagataa accaaaacct 200

 aacttgaaca atctccggaa agaagaaatc ccagtacaag agaaaacccc 250

 taaaaaaagg atggctttag atgacaagct ctaccagaga gacttagaag 300

 ttgcactagc tttatcagtg aaggaacttc caacagtcac cactaatgtg 350

 cagaactctc aagataaaag cattgaaaaa catggcagta gtaaaataga 400

 aacaatgaat aagtctcctc atatctctaa ttgcagtgta gccagtgatt 450

 atttagattt ggataagatt actgtggaag atgatgttgg tggtgttcaa 500

 gggaaaagaa aagcagcatc taaagctgca gcacagcaga ggaagattct 550

 tctggaaggc agtgatggtg atagtgctaa tgacactgaa ccagactttg 600

 cacctggtga agattctgag gatgattctg atttttgtga gagtgaggat 650

 aatgacgaag acttctctat gagaaaaagt aaagttaaag aaattaaaaa 700

 gaaagaagtg aaggtaaaat ccccagtaga aaagaaagag aagaaatcta 750

 aatccaaatg taatgctttg gtgacttcgg tggactctgc tccagctgcc 800

 gtcaaatcag aatctcagtc cttgccaaaa aaggtttctc tgtcttcaga 850

 taccactagg aaaccattag aaatacgcag tccttcagct gaaagcaaga 900

 aacctaaatg ggtcccacca gcggcatctg gaggtagcag aagtagcagc 950

 agcccactgg tggtagtgtc tgtgaagtct cccaatcaga gtctccgcct 1000

 tggcttgtcc agattagcac gagttaaacc tttgcatcca aatgccacta 1050

 gcacctgagt gtggtacagg aggaatgttt ggttgggaga atcacagctt 1100

 tacaagggtg tttatatttg atttgtgttt atatttgagg caggtattgt 1150

 aatataaagg aatccattac catgtcctat aaatgacctc tagccatttt 1200

 atgattatgt tctctgtaaa actcttcaag acttcaatga gaagtttgtt 1250

 tataagaatt atcttctcat acctttcctt gtgaagagcg tattctgttt 1300

 ttctatcagt tcgacatgaa gtccacatca catgctgttc ttttctagtt 1350

 acatgatgtg cctttctagc tttgtctagt ttatagcacc ttaactttaa 1400

 ctgttcagtt ttatctggca gaggaaacat tcttatttct ttcagaagac 1450

 atttctgaaa tcttataagc tacttaagct acgttgtcag ttttatcgca 1500

 aagatgtttt gtattttagc caaatctttt tatagtacaa acttagaatt 1550

 attttacaca ctaaaatggt tgcagtttta tggcatatgt ctccgattta 1600

 gatggttgtt ctctagaaaa tagtatttaa agacatttta tgaaatcttc 1650

 attgtcaaaa cctttaataa aagtggaaat attttgaaat gccctttttc 1700

 ttgataccac tcatccacgt gttcctgatt gtccacattt catgataaaa 1750

 tgagagctct gcagagaatg ttagcctttc tgttgtaaat gtaatcttca 1800

 agtagtcact ttttgttaag ttctttagaa agtagttgtc aagtacttag 1850

 tcatccctat tatgatatga gatagtacag cttttcagga agcttagatc 1900

 tgaatttact ttgaaaaaca attgtaatga atattttata tttacattga 1950

 gaatttcaac tagcttctga tcaattttta ataaaaaatt ttcaaatcat 2000

 gttagctgtt aaaaaatgta taataactca gtttttcttg gtttatggaa 2050

 atatctatat taatgtgaaa ataattaatt tagaattgtg attaaagtga 2100

 gcatttgtct atcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2143

<210> 1072
<211> 335
<212> PRT
<213> Homo sapien

<400> 1072
 Met Val Arg Pro Val Arg His Lys Lys Pro Val Asn Tyr Ser Gln
   1               5                  10                  15

 Phe Asp His Ser Asp Ser Asp Asp Asp Phe Val Ser Ala Thr Val
                  20                  25                  30

 Pro Leu Asn Lys Lys Ser Arg Thr Ala Pro Lys Glu Leu Lys Gln
                  35                  40                  45

 Asp Lys Pro Lys Pro Asn Leu Asn Asn Leu Arg Lys Glu Glu Ile
                  50                  55                  60

 Pro Val Gln Glu Lys Thr Pro Lys Lys Arg Met Ala Leu Asp Asp
                  65                  70                  75

 Lys Leu Tyr Gln Arg Asp Leu Glu Val Ala Leu Ala Leu Ser Val
                  80                  85                  90

 Lys Glu Leu Pro Thr Val Thr Thr Asn Val Gln Asn Ser Gln Asp
                  95                 100                 105

 Lys Ser Ile Glu Lys His Gly Ser Ser Lys Ile Glu Thr Met Asn
                 110                 115                 120

 Lys Ser Pro His Ile Ser Asn Cys Ser Val Ala Ser Asp Tyr Leu
                 125                 130                 135

 Asp Leu Asp Lys Ile Thr Val Glu Asp Asp Val Gly Gly Val Gln
                 140                 145                 150

 Gly Lys Arg Lys Ala Ala Ser Lys Ala Ala Ala Gln Gln Arg Lys
                 155                 160                 165

 Ile Leu Leu Glu Gly Ser Asp Gly Asp Ser Ala Asn Asp Thr Glu
                 170                 175                 180

 Pro Asp Phe Ala Pro Gly Glu Asp Ser Glu Asp Asp Ser Asp Phe
                 185                 190                 195

 Cys Glu Ser Glu Asp Asn Asp Glu Asp Phe Ser Met Arg Lys Ser
                 200                 205                 210

 Lys Val Lys Glu Ile Lys Lys Lys Glu Val Lys Val Lys Ser Pro
                 215                 220                 225

 Val Glu Lys Lys Glu Lys Lys Ser Lys Ser Lys Cys Asn Ala Leu
                 230                 235                 240

 Val Thr Ser Val Asp Ser Ala Pro Ala Ala Val Lys Ser Glu Ser
                 245                 250                 255

 Gln Ser Leu Pro Lys Lys Val Ser Leu Ser Ser Asp Thr Thr Arg
                 260                 265                 270

 Lys Pro Leu Glu Ile Arg Ser Pro Ser Ala Glu Ser Lys Lys Pro
                 275                 280                 285

 Lys Trp Val Pro Pro Ala Ala Ser Gly Gly Ser Arg Ser Ser Ser
                 290                 295                 300

 Ser Pro Leu Val Val Val Ser Val Lys Ser Pro Asn Gln Ser Leu
                 305                 310                 315

 Arg Leu Gly Leu Ser Arg Leu Ala Arg Val Lys Pro Leu His Pro
                 320                 325                 330

 Asn Ala Thr Ser Thr
                 335

<210> 1073
<211> 3689
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2359-2453
<223> Unknown base

<400> 1073
 tgtcagagtg tgactggacg gtgctgtcct aagacaaagt cccagtggag 50

 atggggatag gtcagaaacc tggttttaga aggccatgta ggtatcaaga 100

 tgtcaccacc agctgagatt tgccacatcc gccccaccct cagccccccg 150

 actgggcaga gccaagcagc ttcccacact gtcgctgtgg agcaccccct 200

 ttgggtggtg ctttagagga aggagtctgg agtggggccc cgggctgtct 250

 tttgcttggg ctccttcaga aggaccagct gtctctaggg gttgcctgag 300

 agtggtgtct tgtgtgctta tttcttctct taactgtttt ctgcaggtac 350

 agctggataa cttgccagga atgagtctcg tggctgggaa agcacttagc 400

 tctgcccgga tgtcggatgc agttctcagt cagtcttcgc tcatgggcag 450

 ccagcagttt caggatgggg aaaatgagga atgtggggca agcctgggag 500

 gtcatgagca cccagacctg agtgatggca gccagcattt aaactcctct 550

 tgctatccat ctacgtgtat tacagacatt ctgctcagct acaagcaccc 600

 cgaagtctcc ttcagcatgg agcaggcagg cgtgtaacaa gaaacagaga 650

 gtgagtgtca ccctggccag agccaaacca gccctgtggc ccagtgcctg 700

 ctcccaatcc catcaggagc ttcagcccat gtgttgtggt ggccagtgca 750

 gtcgacagta ccacgcctcc cctcgtggcc ttcacagttt cttgcttttc 800

 attaacgacg ctgctagttt tagggcgcga ggtaggggtg ggggtgtgca 850

 gaagaaatgc taaacacagt ctcttggttg ggttatggga ataagacaca 900

 agactcgccg tgtgttacag gtgctctagc cttcatagcg acagaagtga 950

 gctacggctc cagaggatgc aggtgacctc cggtcagcat aatgaggaaa 1000

 ggaggaagtc cttaaactca gtcctaaaag acaaaacctg gcaggaaaat 1050

 atgtccagcc atatttttta aggccataca gaagcaagtg gcaggatatt 1100

 ccagattagg gaaatgtgtg atgagaggcc catggtagaa agaatgggga 1150

 aattggcttg tttggctgga gtaatgcaaa gagtacacag caggcaccat 1200

 tggttgtatc tggaaaatcc ttgacagaag aggcctgatg aaagggaagc 1250

 cacttggcaa atccacatca gagcctcagt atggcaagct acctgaacac 1300

 ctgagggaaa gtaaacccgt tgcatttttt aaaaggtttt aaatggaata 1350

 tttgagcctt tctcttttca aactaattct cctctgtgtc tgctttattc 1400

 caggttttgt gtacagcttg ggaatgaaaa ggttgattgt aaacccacag 1450

 tatctagcag cgttgtgcca aattgccctt gtgtttctct ccacccaaaa 1500

 tatcacagct gctttcctca catttggttc atccgtgtgc tgttcttttg 1550

 ggttctgaga gggttttgcc atgtttgctt gtatgaccaa gtcaccaagg 1600

 aaataaacag gaaggaaatc catgttctcc atcttttgtg aaagtatatt 1650

 tgagttggtg gttttttgtt ttgtttgggg gtttgtgttt tgttttgctt 1700

 tttggtactg ttttcttcca gaggtgatat actttctttt ttttcttcct 1750

 ttctattttt ttctttcgtt ccttttttga aacaggagag caaagcagtt 1800

 agagttcaga ggccagcggc ctcagggcca ctccctccct agccttcatc 1850

 agcagagcac cctccatccc cctgcattgc tcttctgtga aagcaaatac 1900

 taaaggatgc catcctctgg aatcctaatg gcaggcaaag ggagagagga 1950

 agggtgacgg cttctggcac ttagaaaaca aaaagaacaa aaaaagagaa 2000

 acccccaagc ctggaacgca gagaggtctt tactgctggg atccacggaa 2050

 aacatgtctg tcctagccaa gatcatatga agagtttggc acggaggctg 2100

 agaatgacct ggcatagatg gtttgccagt taggatgtct caatttgagc 2150

 ctttgctttt ggtggataac tcagctcccc tcttgtaacc tggaaagttg 2200

 gttgccttta tcatcctgct ggttttatcc atggactgaa cacccaacag 2250

 cagtgcacta tgctttctat ggcatctttc attctcattt tatattgtgc 2300

 tataaaaagg attgtttctc catatatata ttatatatgt gtgtatatat 2350

 ataatatann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2450

 nnngctctcc tctttcagcc tctttgtcac agggaagaag tgtaggaggt 2500

 tgccttgggc cctgcctctc tcctaacctc ctcttcccca ctgggtaccc 2550

 tcagccccta tattttaatt cttgatcatg tagaaattgt ttttggtaaa 2600

 tgttgatatt attgttatta tcattattaa taaataaaga gaaaaggaat 2650

 ttttgtttaa atgagaaatg tttaaccaga ttctgttcta tttgaattgt 2700

 gacttgcacc ttttgttcaa agtatttcct ttaggcattg taattgtgaa 2750

 cagctcttac ttgtgccagt gacagatgca gtggtctcct ttccccagtt 2800

 gaagcagtgc atacgcagta gctattattt gtgttatctt tatttctctt 2850

 cattgttaga aaccaaagtc ttctctgctg gctggggctg agagagggtc 2900

 tgggttatct ccttctgatc ttcaaaacaa gagagagacc ttgaatacac 2950

 tgactcttcc accctttttt tttctgggaa aggagagcaa gaggtcccga 3000

 gtcccctcct agtctttcat cctgaatttg cacagaggaa agcgggtgcc 3050

 cggcatggcc atcctgatgt tgctggcggg atccccatgc accttgtcct 3100

 tctccactga tactggcagc tcggctcctg gacccaagat cccttgagtg 3150

 gaattctgca gtgcaagagc ccttcgtggg agctgtccca tgtttccatg 3200

 gtccccagtc tcccctccac ttggtggggt caccaactac tcaccagaag 3250

 ggggcttacc aagaaagccc taaaaagctg ttgacttatc tgcgcttgtt 3300

 ccaactctta tgcccccaac ctgccctacc accaccacgc gctcagcctg 3350

 atgtgtttac atggtactgt atgtatggga gagcagactg caccctccag 3400

 caacaacaga tgaaagccag tgagcctact aaccgtgcca tcttgcaaac 3450

 tacactttaa aaaaaactca ttgctttgta ttgtagtaac caatatgtgc 3500

 agtatacgtt gaatgtatat gaacatactt tcctatttct gttctttgaa 3550

 aatgtcagaa atattttttt ctttctcatt ttatgttgaa ctaaaaagga 3600

 ttaaaaaaaa aatctccaaa aaaatctatg tcgggtgcgg agaaagaggt 3650

 aatgaaatgg caggaaatcg atatgcaagc ttatcgata 3689

<210> 1074
<211> 19
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2359-2453
<223> Unknown amino acid

<400> 1074
 Cys Gln Ser Val Thr Gly Arg Cys Cys Pro Lys Thr Lys Ser Gln
   1               5                  10                  15

 Trp Arg Trp Gly


<210> 1075
<211> 1315
<212> DNA
<213> Homo sapien

<400> 1075
 cggggatttt gtgccccgat ctatagttcc ttgagtctcc acacacactc 50

 ctcacagaga tctgtagcgt aggtacgtga cagctctgcc tacatctgac 100

 gtccggagtc attaaccagg aatgtatgtg tgtctgtgtg tctctctgtg 150

 gagtcgtcag aattcttcat aggggttaag ctaaaaaagc gaggcgagga 200

 gcccctctcc aatggctcag ttttgctgaa taatcacgtg tgaatcgagg 250

 ggcgggcttt tggcaggcag atcttactag tatttactac caagctctac 300

 tccagattaa ccatcccagt ccttctgtca gtctccgatg ccatcatgca 350

 gcctggttag gagcaaagga aaggggaaaa agaaaaacga ctaattcatc 400

 ttttcctgat cgtcaggacc ctaaagaatg gccgagcctt gggggaacga 450

 gttggcgtcc gcagctgcca ggggggacct agagcaactt actagtttgt 500

 tgcaaaataa tgtaaacgtc aatgcacaaa atggatttgg aaggactgcg 550

 ctgcaggtta tgaaacttgg aaatcccgag attgccagga gactgctact 600

 tagaggtgct aatcccgatt tgaaagaccg aactggtttc gctgtcattc 650

 atgatgcggc cagagcaggt ttcctggaca ctttacagac tttgctggag 700

 tttcaagctg atgttaacat cgaggataat gaagggaacc tgcccttgca 750

 cttggctgcc aaagaaggcc acctccgggt ggtggagttc ctggtgaagc 800

 acacggccag caatgtgggg catcggaacc ataaggggga caccgcctgt 850

 gatttggcca ggctctatgg gaggaatgag gttgttagcc tgatgcaggc 900

 aaacggggct gggggagcca caaatcttca ataaacgtgg ggagggctcc 950

 cccacgttgc ctctacttta tcaattaact gagtagctct cctgactttt 1000

 aatgtcattt gttaaaatac agttctgtca tatgttaagc agctaaattt 1050

 tctgaaactg cataagtgaa aatcttacaa caggtttatg aatatattta 1100

 agcaacatct ttttaacctg caaaatctgt tctaacatgt aattgcagat 1150

 aactttgact ttcttctgaa tattttatct ttccttggct tttcccttgc 1200

 ttcccctttt gccaatctca acacccaagt tgaagacttt gtttttaaaa 1250

 tggtttgtcc tgatgctttt gtctaattaa aacactttca aaacaggaaa 1300

 aaaaaaaaaa aaaaa 1315

<210> 1076
<211> 168
<212> PRT
<213> Homo sapien

<400> 1076
 Met Ala Glu Pro Trp Gly Asn Glu Leu Ala Ser Ala Ala Ala Arg
   1               5                  10                  15

 Gly Asp Leu Glu Gln Leu Thr Ser Leu Leu Gln Asn Asn Val Asn
                  20                  25                  30

 Val Asn Ala Gln Asn Gly Phe Gly Arg Thr Ala Leu Gln Val Met
                  35                  40                  45

 Lys Leu Gly Asn Pro Glu Ile Ala Arg Arg Leu Leu Leu Arg Gly
                  50                  55                  60

 Ala Asn Pro Asp Leu Lys Asp Arg Thr Gly Phe Ala Val Ile His
                  65                  70                  75

 Asp Ala Ala Arg Ala Gly Phe Leu Asp Thr Leu Gln Thr Leu Leu
                  80                  85                  90

 Glu Phe Gln Ala Asp Val Asn Ile Glu Asp Asn Glu Gly Asn Leu
                  95                 100                 105

 Pro Leu His Leu Ala Ala Lys Glu Gly His Leu Arg Val Val Glu
                 110                 115                 120

 Phe Leu Val Lys His Thr Ala Ser Asn Val Gly His Arg Asn His
                 125                 130                 135

 Lys Gly Asp Thr Ala Cys Asp Leu Ala Arg Leu Tyr Gly Arg Asn
                 140                 145                 150

 Glu Val Val Ser Leu Met Gln Ala Asn Gly Ala Gly Gly Ala Thr
                 155                 160                 165

 Asn Leu Gln


<210> 1077
<211> 2150
<212> DNA
<213> Homo sapien

<400> 1077
 ctcgagccac gaaggccccg ctgtcctgtc tagcagatac ttgcacggtt 50

 tacagaaatt cggtccctgg gtcgtgtcag gaaactggaa aaaaggtcat 100

 aagcatgaag cgcagttcag tttccagcgg tggtgctggc cgcctctcca 150

 tgcaggagtt aagatcccag gatgtaaata aacaaggcct ctatacccct 200

 caaaccaaag agaaaccaac ctttggaaag ttgagtataa acaaaccgac 250

 atctgaaaga aaagtctcgc tatttggcaa aagaactagt ggacatggat 300

 cccggaatag tcaacttggt atattttcca gttctgagaa aatcaaggac 350

 ccgagaccac ttaatgacaa agcattcatt cagcagtgta ttcgacaact 400

 ctgtgagttt cttacagaaa atggttatgc acataatgtg tccatgaaat 450

 ctctacaagc tccctctgtt aaagacttcc tgaagatctt cacatttctt 500

 tatggcttcc tgtgcccctc atacgaactt cctgacacaa agtttgaaga 550

 agaggttcca agaatcttta aagaccttgg gtatcctttt gcactatcca 600

 aaagctccat gtacacagtg ggggctcctc atacatggcc tcacattgtg 650

 gcagccttag tttggctaat agactgcatc aagatacata ctgccatgaa 700

 agaaagctca cctttatttg atgatgggca gccttgggga gaagaaactg 750

 aagatggaat tatgcataat aagttgtttt tggactacac cataaaatgc 800

 tatgagagtt ttatgagtgg tgccgacagc tttgatgaga tgaatgcaga 850

 gctgcagtca aaactgaagg atttatttaa tgtggatgct tttaagctgg 900

 aatcattaga agcaaaaaac agagcattga atgaacagat tgcaagattg 950

 gaacaagaaa gagaaaaaga accgaatcgt ctagagtcgt tgagaaaact 1000

 gaaggcttcc ttacaaggag atgttcaaaa gtatcaggca tacatgagca 1050

 atttggagtc tcattcagcc attcttgacc agaaattaaa tggtctcaat 1100

 gaggaaattg ctagagtaga actagaatgt gaaacaataa aacaggagaa 1150

 cactcgacta cagaatatca ttgacaacca gaagtactca gttgcagaca 1200

 ttgagcgaat aaatcatgaa agaaatgaat tgcagcagac tattaataaa 1250

 ttaaccaagg acctggaagc tgaacaacag aagttgtgga atgaggagtt 1300

 aaaatatgcc agaggcaaag aagcgattga aacacaatta gcagagtatc 1350

 acaaattggc tagaaaatta aaacttattc ctaaaggtgc tgagaattcc 1400

 aaaggttatg actttgaaat taagtttaat cccgaggctg gtgccaactg 1450

 ccttgtcaaa tacagggctc aagtttatgt acctcttaag gaactcctga 1500

 atgaaactga agaagaaatt aataaagccc taaataaaaa aatgggtttg 1550

 gaggatactt tagaacaatt gaatgcaatg ataacagaaa gcaagagaag 1600

 tgtgagaact ctgaaagaag aagttcaaaa gctggatgat ctttaccaac 1650

 aaaaaattaa ggaagcagag gaagaggatg aaaaatgtgc cagtgagctt 1700

 gagtccttgg agaaacacaa gcacctgcta gaaagtactg ttaaccaggg 1750

 gctcagtgaa gctatgaatg aattagatgc tgttcagcgg gaataccaac 1800

 tagttgtgca aaccacgact gaagaaagac gaaaagtggg aaataacttg 1850

 caacgtctgt tagagatggt tgctacacat gttgggtctg tagagaaaca 1900

 tcttgaggag cagattgcta aagttgatag agaatatgaa gaatgcatgt 1950

 cagaagatct ctcggaaaat attaaagaga ttagagataa gtatgagaag 2000

 aaagctactc taattaagtc ttctgaagaa tgaagataaa atgttgatca 2050

 tgtatatata tccatagtga ataaaattgt ctcagtaaaa aaaaaaaaaa 2100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2150

<210> 1078
<211> 642
<212> PRT
<213> Homo sapien

<400> 1078
 Met Lys Arg Ser Ser Val Ser Ser Gly Gly Ala Gly Arg Leu Ser
   1               5                  10                  15

 Met Gln Glu Leu Arg Ser Gln Asp Val Asn Lys Gln Gly Leu Tyr
                  20                  25                  30

 Thr Pro Gln Thr Lys Glu Lys Pro Thr Phe Gly Lys Leu Ser Ile
                  35                  40                  45

 Asn Lys Pro Thr Ser Glu Arg Lys Val Ser Leu Phe Gly Lys Arg
                  50                  55                  60

 Thr Ser Gly His Gly Ser Arg Asn Ser Gln Leu Gly Ile Phe Ser
                  65                  70                  75

 Ser Ser Glu Lys Ile Lys Asp Pro Arg Pro Leu Asn Asp Lys Ala
                  80                  85                  90

 Phe Ile Gln Gln Cys Ile Arg Gln Leu Cys Glu Phe Leu Thr Glu
                  95                 100                 105

 Asn Gly Tyr Ala His Asn Val Ser Met Lys Ser Leu Gln Ala Pro
                 110                 115                 120

 Ser Val Lys Asp Phe Leu Lys Ile Phe Thr Phe Leu Tyr Gly Phe
                 125                 130                 135

 Leu Cys Pro Ser Tyr Glu Leu Pro Asp Thr Lys Phe Glu Glu Glu
                 140                 145                 150

 Val Pro Arg Ile Phe Lys Asp Leu Gly Tyr Pro Phe Ala Leu Ser
                 155                 160                 165

 Lys Ser Ser Met Tyr Thr Val Gly Ala Pro His Thr Trp Pro His
                 170                 175                 180

 Ile Val Ala Ala Leu Val Trp Leu Ile Asp Cys Ile Lys Ile His
                 185                 190                 195

 Thr Ala Met Lys Glu Ser Ser Pro Leu Phe Asp Asp Gly Gln Pro
                 200                 205                 210

 Trp Gly Glu Glu Thr Glu Asp Gly Ile Met His Asn Lys Leu Phe
                 215                 220                 225

 Leu Asp Tyr Thr Ile Lys Cys Tyr Glu Ser Phe Met Ser Gly Ala
                 230                 235                 240

 Asp Ser Phe Asp Glu Met Asn Ala Glu Leu Gln Ser Lys Leu Lys
                 245                 250                 255

 Asp Leu Phe Asn Val Asp Ala Phe Lys Leu Glu Ser Leu Glu Ala
                 260                 265                 270

 Lys Asn Arg Ala Leu Asn Glu Gln Ile Ala Arg Leu Glu Gln Glu
                 275                 280                 285

 Arg Glu Lys Glu Pro Asn Arg Leu Glu Ser Leu Arg Lys Leu Lys
                 290                 295                 300

 Ala Ser Leu Gln Gly Asp Val Gln Lys Tyr Gln Ala Tyr Met Ser
                 305                 310                 315

 Asn Leu Glu Ser His Ser Ala Ile Leu Asp Gln Lys Leu Asn Gly
                 320                 325                 330

 Leu Asn Glu Glu Ile Ala Arg Val Glu Leu Glu Cys Glu Thr Ile
                 335                 340                 345

 Lys Gln Glu Asn Thr Arg Leu Gln Asn Ile Ile Asp Asn Gln Lys
                 350                 355                 360

 Tyr Ser Val Ala Asp Ile Glu Arg Ile Asn His Glu Arg Asn Glu
                 365                 370                 375

 Leu Gln Gln Thr Ile Asn Lys Leu Thr Lys Asp Leu Glu Ala Glu
                 380                 385                 390

 Gln Gln Lys Leu Trp Asn Glu Glu Leu Lys Tyr Ala Arg Gly Lys
                 395                 400                 405

 Glu Ala Ile Glu Thr Gln Leu Ala Glu Tyr His Lys Leu Ala Arg
                 410                 415                 420

 Lys Leu Lys Leu Ile Pro Lys Gly Ala Glu Asn Ser Lys Gly Tyr
                 425                 430                 435

 Asp Phe Glu Ile Lys Phe Asn Pro Glu Ala Gly Ala Asn Cys Leu
                 440                 445                 450

 Val Lys Tyr Arg Ala Gln Val Tyr Val Pro Leu Lys Glu Leu Leu
                 455                 460                 465

 Asn Glu Thr Glu Glu Glu Ile Asn Lys Ala Leu Asn Lys Lys Met
                 470                 475                 480

 Gly Leu Glu Asp Thr Leu Glu Gln Leu Asn Ala Met Ile Thr Glu
                 485                 490                 495

 Ser Lys Arg Ser Val Arg Thr Leu Lys Glu Glu Val Gln Lys Leu
                 500                 505                 510

 Asp Asp Leu Tyr Gln Gln Lys Ile Lys Glu Ala Glu Glu Glu Asp
                 515                 520                 525

 Glu Lys Cys Ala Ser Glu Leu Glu Ser Leu Glu Lys His Lys His
                 530                 535                 540

 Leu Leu Glu Ser Thr Val Asn Gln Gly Leu Ser Glu Ala Met Asn
                 545                 550                 555

 Glu Leu Asp Ala Val Gln Arg Glu Tyr Gln Leu Val Val Gln Thr
                 560                 565                 570

 Thr Thr Glu Glu Arg Arg Lys Val Gly Asn Asn Leu Gln Arg Leu
                 575                 580                 585

 Leu Glu Met Val Ala Thr His Val Gly Ser Val Glu Lys His Leu
                 590                 595                 600

 Glu Glu Gln Ile Ala Lys Val Asp Arg Glu Tyr Glu Glu Cys Met
                 605                 610                 615

 Ser Glu Asp Leu Ser Glu Asn Ile Lys Glu Ile Arg Asp Lys Tyr
                 620                 625                 630

 Glu Lys Lys Ala Thr Leu Ile Lys Ser Ser Glu Glu
                 635                 640

<210> 1079
<211> 4877
<212> DNA
<213> Homo sapien

<400> 1079
 gcccgaaacc cggaagtgag cggcggcagc tgcgaggctc ggagaaacag 50

 gcgccgcggg ctccgcgccc ggccggaccc gggcccgaga tcatgatgct 100

 gccgccaccg ccgccaccac ggagcgagaa gcccagatag acgccccggc 150

 ggccccgggt cctggagtcc cgccgcctgc tgcccggccg aggaccccac 200

 cccgcctgcc gcccgatgct tgcagtgggg cccgccatgg acagggatta 250

 cccgcagcat gaacccccgc cggcgggcag cctcctgtac agcccgccgc 300

 ccctgcagag cgccatgctg cactgcccct actggaacac cttctcgctg 350

 ccgccatacc ctgccttctc cagcgacagc cgcccgttca tgagctccgc 400

 ctccttcctc ggcagccagc cctgcccaga caccagctat gcccccgtgg 450

 ccaccgcctc cagcttgcca ccaaagacct gcgactttgc tcaggactcc 500

 tcctattttg aggacttctc caacatctcc atcttctcct cgtccgtgga 550

 ctccctgtcg gacatcgtgg acacgcccga cttcctgccg gctgacagcc 600

 tcaaccaggt gtccaccatc tgggacgata accctgcccc ctccacccac 650

 gataagctgt tccagctcag caggccgttt gcaggcttcg aggactttct 700

 gccctcccac agcaccccgc ttctcgtcag ctaccaggag cagagtgtgc 750

 agagccagcc agaggaggag gacgaggctg aggaggagga ggcggaggag 800

 ctggggcaca cagagaccta cgccgactac gtgccgtcca agtccaagat 850

 cgggaagcag cacccagacc gcgtggtgga gaccagcaca ctgtccagcg 900

 tcccaccccc agacatcacc tacaccctgg ccctgccctc ggacagcggg 950

 gccctgtctg ccctgcagct agaggccatc acctacgcct gccagcaaca 1000

 cgaggtcctg ctccccagcg ggcagcgcgc gggctttctc atcggcgatg 1050

 gggccggcgt gggcaaaggc cggacggtgg ccggagtcat cctggagaac 1100

 cacctgcgcg gccggaagaa agcattgtgg ttcagcgtct ccaacgacct 1150

 caagtacgat gcggagcgcg acctgcggga catcgaagcc acgggcatcg 1200

 cggtgcacgc gctcagcaag atcaagtacg gtgacaccac tacctcagag 1250

 ggcgtcctct tcgccaccta ctccgccctg attggggaga gccaggccgg 1300

 tggccagcac cgcactcgcc tccggcagat cctggactgg tgtggggagg 1350

 cctttgaggg cgtcatcgtg ttcgacgagt gtcacaaagc caagaatgcc 1400

 ggctccacca agatgggcaa ggccgtgcta gacctgcaga acaagctgcc 1450

 cctggcccgc gtggtctacg ccagcgccac aggtgcctct gagcctcgga 1500

 acatgatcta catgagccgc ttgggtatct ggggcgaggg cacacccttc 1550

 cggaactttg aggagttcct gcacgccatc gagaagaggg gcgttggcgc 1600

 catggagatc gtggccatgg acatgaaggt cagcggcatg tacatcgcac 1650

 gccagctcag cttctccggc gtcaccttcc gcatcgagga gatcccgctg 1700

 gccccagcct tcgagtgcgt ctacaaccgc gcagccctgc tgtgggccga 1750

 ggccctgaac gtgttccagc aggcggccga ctggatcggc ctggagtcgc 1800

 gcaagtccct gtggggccag ttctggtcgg cacaccagcg cttcttcaag 1850

 tatctgtgca tcgcagccaa ggtgcgccgg ctggtggagc tggcccgaga 1900

 ggagctggcg cgagacaagt gcgtggtcat cgggctgcag tccacgggcg 1950

 aggcgcgcac gcgggaggtg ctgggggaga acgatgggca cctcaactgc 2000

 ttcgtctcgg ccgctgaagg cgtgttcctg tcgctaattc agaagcactt 2050

 tccgtccacc aagagaaagc gggacagagg agcgggcagc aagcggaaac 2100

 ggcgacctcg gggacgcggg gccaaagccc cccggctggc gtgcgagaca 2150

 gcgggcgtca tccgcatcag tgacgacagc agcacggagt cggaccctgg 2200

 cctggacagc gacttcaact cctcccccga gtccctggtg gatgacgacg 2250

 ttgtcatcgt tgatgcagtc gggctcccca gtgacgaccg gggatccctg 2300

 tgcctcctgc agagagaccc gcatggcccc ggggtcctgg agcgggtgga 2350

 gcggctgaag caggatctgc tggacaaagt gcgccggctg ggccgggaac 2400

 tgccagtcaa caccctggac gagctcatcg accagctggg cggcccccag 2450

 cgggtggcgg agatgaccgg caggaaaggc cgcgtggtgt ccaggcccga 2500

 cgggacggtg gccttcgagt cgcgggcaga gcagggtctg tccatcgacc 2550

 acgtgaacct cagggagaag cagcgcttca tgagcggcga gaagctcgtg 2600

 gccatcatct cggaggcctc cagctcgggt gtctccctcc aagccgaccg 2650

 ccgtgtccag aaccagcggc gccgcgtgca catgaccttg gagctgccgt 2700

 ggagcgccga ccgcgccatc cagcagttcg gccgcaccca ccggtccaac 2750

 caggtctccg cgccagagta tgtcttcctc atctcggagc tggccgggga 2800

 gcgccggttc gcctccatcg tggccaagcg cctggagagt ctgggggccc 2850

 tgacccacgg agaccgccgc gccacggagt cccgtgacct cagcaagtac 2900

 aactttgaga acaagtatgg cacccgggcc ctgcactgtg tcctcaccac 2950

 catcctgagc cagactgaga acaaagtgcc tgtgccccag ggataccctg 3000

 gaggggtccc caccttcttc cgggacatga agcagggcct gctgtctgtg 3050

 ggcattggtg gccgggagtc ccggaatggc tgcctggacg tggagaagga 3100

 ctgttccatc accaagttcc tgaaccgcat cctggggctg gaggtgcaca 3150

 agcagaatgc cctgttccag tacttctcag acaccttcga ccacctcatc 3200

 gagatggaca agcgggaggg caaatacgac atgggcatcc tggaccttgc 3250

 tcccggtatc gaggagatct acgaggagag ccagcaggtg ttcctggctc 3300

 ccgggcaccc gcaggacggg caggtggtct tctacaagat cagcgtggac 3350

 cgcggcctga agtgggagga cgcctttgcc aagtcgctgg cgctgacggg 3400

 cccctatgac ggcttctacc tctcctacaa ggtccgcggt aacaagccca 3450

 gctgcctgct ggcggagcag aaccgcggcc agttcttcac ggtgtacaag 3500

 cccaacatcg gccggcagag ccagctggag gccctggaca gcctccgccg 3550

 caagttccac cgggtcaccg cggaggaggc caaggagccc tgggagagtg 3600

 gctacgcttt gtcgctgacg cactgcagcc acagcgcctg gaaccggcac 3650

 tgccggctgg cgcaggaggg taaggactgc ctgcaggggc tgcggctgcg 3700

 gcaccactac atgctgtgcg gcgcgctgct gcgcgtgtgg ggccgcatcg 3750

 ccgccgtcat ggccgacgtc agcagcagca gctacctgca gatcgtgcgg 3800

 ctgaagacca aggacaggaa gaagcaagtg ggcatcaaga tccccgaggg 3850

 ctgcgtgcgc cgggtgctgc aggagctgcg gctgatggat gcggacgtga 3900

 agcgcaggca ggcgcccgcc ctgggctgcc ccgccccgcc cgccccgcgc 3950

 ccgctggcgc tgccttgcgg ccccggagag gtgctggacc tcacctacag 4000

 ccccccggcc gaggccttcc cgccgccccc gcacttctct ttcccggcgc 4050

 cgctgtccct ggacgccggc cccggcgtcg tgccgctggg cacccccgac 4100

 gcccaggccg accctgcggc cctcgcgcac cagggctgcg acatcaactt 4150

 caaggaggtg ctggaggaca tgctgcgctc gctgcacgcg gggccgccct 4200

 ccgagggcgc gctgggggag ggcgcggggg cggggggcgc ggcgggcggt 4250

 ggtcccgagc ggcagagcgt gatccagttc agcccaccct tccccggcgc 4300

 ccaggctcct ctctgacacg cctttaggcg aaacatgccc caagacacag 4350

 ggaccgtttc tcccctagga gcagcggtgg ggagcagggc caaggtcccc 4400

 tgaccactgc tcagaggagc cctaggccct ggccgcagtg ccttcagcgc 4450

 ccgacccggg cccccacctg gtcagccctg gcggggccca ctcaggacag 4500

 ctgggggccg gggcgtggca gggccctctc tgtgcctctc ctcctaagta 4550

 ggaaggggct ccgggtggct gctctgggac tgggcaccca caagggctca 4600

 gtgggcccaa acccttgaaa tccgtgaaac cgggtggtcc caagagctag 4650

 aaactcagga aaccccaggt gctcagggcc ccgcgtctcg ggggctccgt 4700

 ggggcagacc cctgctaata tatgcaattc tccctccccc agcccttccc 4750

 tgacccctaa gttattgccc gctcacctct cccaggcccc aggccgcgga 4800

 gctggcaggg tggcgcctgc ggtttctatg tatttatagc aagttctgat 4850

 gtacatatgt aaaggacttt tttaaat 4877

<210> 1080
<211> 1366
<212> PRT
<213> Homo sapien

<400> 1080
 Met Leu Ala Val Gly Pro Ala Met Asp Arg Asp Tyr Pro Gln His
   1               5                  10                  15

 Glu Pro Pro Pro Ala Gly Ser Leu Leu Tyr Ser Pro Pro Pro Leu
                  20                  25                  30

 Gln Ser Ala Met Leu His Cys Pro Tyr Trp Asn Thr Phe Ser Leu
                  35                  40                  45

 Pro Pro Tyr Pro Ala Phe Ser Ser Asp Ser Arg Pro Phe Met Ser
                  50                  55                  60

 Ser Ala Ser Phe Leu Gly Ser Gln Pro Cys Pro Asp Thr Ser Tyr
                  65                  70                  75

 Ala Pro Val Ala Thr Ala Ser Ser Leu Pro Pro Lys Thr Cys Asp
                  80                  85                  90

 Phe Ala Gln Asp Ser Ser Tyr Phe Glu Asp Phe Ser Asn Ile Ser
                  95                 100                 105

 Ile Phe Ser Ser Ser Val Asp Ser Leu Ser Asp Ile Val Asp Thr
                 110                 115                 120

 Pro Asp Phe Leu Pro Ala Asp Ser Leu Asn Gln Val Ser Thr Ile
                 125                 130                 135

 Trp Asp Asp Asn Pro Ala Pro Ser Thr His Asp Lys Leu Phe Gln
                 140                 145                 150

 Leu Ser Arg Pro Phe Ala Gly Phe Glu Asp Phe Leu Pro Ser His
                 155                 160                 165

 Ser Thr Pro Leu Leu Val Ser Tyr Gln Glu Gln Ser Val Gln Ser
                 170                 175                 180

 Gln Pro Glu Glu Glu Asp Glu Ala Glu Glu Glu Glu Ala Glu Glu
                 185                 190                 195

 Leu Gly His Thr Glu Thr Tyr Ala Asp Tyr Val Pro Ser Lys Ser
                 200                 205                 210

 Lys Ile Gly Lys Gln His Pro Asp Arg Val Val Glu Thr Ser Thr
                 215                 220                 225

 Leu Ser Ser Val Pro Pro Pro Asp Ile Thr Tyr Thr Leu Ala Leu
                 230                 235                 240

 Pro Ser Asp Ser Gly Ala Leu Ser Ala Leu Gln Leu Glu Ala Ile
                 245                 250                 255

 Thr Tyr Ala Cys Gln Gln His Glu Val Leu Leu Pro Ser Gly Gln
                 260                 265                 270

 Arg Ala Gly Phe Leu Ile Gly Asp Gly Ala Gly Val Gly Lys Gly
                 275                 280                 285

 Arg Thr Val Ala Gly Val Ile Leu Glu Asn His Leu Arg Gly Arg
                 290                 295                 300

 Lys Lys Ala Leu Trp Phe Ser Val Ser Asn Asp Leu Lys Tyr Asp
                 305                 310                 315

 Ala Glu Arg Asp Leu Arg Asp Ile Glu Ala Thr Gly Ile Ala Val
                 320                 325                 330

 His Ala Leu Ser Lys Ile Lys Tyr Gly Asp Thr Thr Thr Ser Glu
                 335                 340                 345

 Gly Val Leu Phe Ala Thr Tyr Ser Ala Leu Ile Gly Glu Ser Gln
                 350                 355                 360

 Ala Gly Gly Gln His Arg Thr Arg Leu Arg Gln Ile Leu Asp Trp
                 365                 370                 375

 Cys Gly Glu Ala Phe Glu Gly Val Ile Val Phe Asp Glu Cys His
                 380                 385                 390

 Lys Ala Lys Asn Ala Gly Ser Thr Lys Met Gly Lys Ala Val Leu
                 395                 400                 405

 Asp Leu Gln Asn Lys Leu Pro Leu Ala Arg Val Val Tyr Ala Ser
                 410                 415                 420

 Ala Thr Gly Ala Ser Glu Pro Arg Asn Met Ile Tyr Met Ser Arg
                 425                 430                 435

 Leu Gly Ile Trp Gly Glu Gly Thr Pro Phe Arg Asn Phe Glu Glu
                 440                 445                 450

 Phe Leu His Ala Ile Glu Lys Arg Gly Val Gly Ala Met Glu Ile
                 455                 460                 465

 Val Ala Met Asp Met Lys Val Ser Gly Met Tyr Ile Ala Arg Gln
                 470                 475                 480

 Leu Ser Phe Ser Gly Val Thr Phe Arg Ile Glu Glu Ile Pro Leu
                 485                 490                 495

 Ala Pro Ala Phe Glu Cys Val Tyr Asn Arg Ala Ala Leu Leu Trp
                 500                 505                 510

 Ala Glu Ala Leu Asn Val Phe Gln Gln Ala Ala Asp Trp Ile Gly
                 515                 520                 525

 Leu Glu Ser Arg Lys Ser Leu Trp Gly Gln Phe Trp Ser Ala His
                 530                 535                 540

 Gln Arg Phe Phe Lys Tyr Leu Cys Ile Ala Ala Lys Val Arg Arg
                 545                 550                 555

 Leu Val Glu Leu Ala Arg Glu Glu Leu Ala Arg Asp Lys Cys Val
                 560                 565                 570

 Val Ile Gly Leu Gln Ser Thr Gly Glu Ala Arg Thr Arg Glu Val
                 575                 580                 585

 Leu Gly Glu Asn Asp Gly His Leu Asn Cys Phe Val Ser Ala Ala
                 590                 595                 600

 Glu Gly Val Phe Leu Ser Leu Ile Gln Lys His Phe Pro Ser Thr
                 605                 610                 615

 Lys Arg Lys Arg Asp Arg Gly Ala Gly Ser Lys Arg Lys Arg Arg
                 620                 625                 630

 Pro Arg Gly Arg Gly Ala Lys Ala Pro Arg Leu Ala Cys Glu Thr
                 635                 640                 645

 Ala Gly Val Ile Arg Ile Ser Asp Asp Ser Ser Thr Glu Ser Asp
                 650                 655                 660

 Pro Gly Leu Asp Ser Asp Phe Asn Ser Ser Pro Glu Ser Leu Val
                 665                 670                 675

 Asp Asp Asp Val Val Ile Val Asp Ala Val Gly Leu Pro Ser Asp
                 680                 685                 690

 Asp Arg Gly Ser Leu Cys Leu Leu Gln Arg Asp Pro His Gly Pro
                 695                 700                 705

 Gly Val Leu Glu Arg Val Glu Arg Leu Lys Gln Asp Leu Leu Asp
                 710                 715                 720

 Lys Val Arg Arg Leu Gly Arg Glu Leu Pro Val Asn Thr Leu Asp
                 725                 730                 735

 Glu Leu Ile Asp Gln Leu Gly Gly Pro Gln Arg Val Ala Glu Met
                 740                 745                 750

 Thr Gly Arg Lys Gly Arg Val Val Ser Arg Pro Asp Gly Thr Val
                 755                 760                 765

 Ala Phe Glu Ser Arg Ala Glu Gln Gly Leu Ser Ile Asp His Val
                 770                 775                 780

 Asn Leu Arg Glu Lys Gln Arg Phe Met Ser Gly Glu Lys Leu Val
                 785                 790                 795

 Ala Ile Ile Ser Glu Ala Ser Ser Ser Gly Val Ser Leu Gln Ala
                 800                 805                 810

 Asp Arg Arg Val Gln Asn Gln Arg Arg Arg Val His Met Thr Leu
                 815                 820                 825

 Glu Leu Pro Trp Ser Ala Asp Arg Ala Ile Gln Gln Phe Gly Arg
                 830                 835                 840

 Thr His Arg Ser Asn Gln Val Ser Ala Pro Glu Tyr Val Phe Leu
                 845                 850                 855

 Ile Ser Glu Leu Ala Gly Glu Arg Arg Phe Ala Ser Ile Val Ala
                 860                 865                 870

 Lys Arg Leu Glu Ser Leu Gly Ala Leu Thr His Gly Asp Arg Arg
                 875                 880                 885

 Ala Thr Glu Ser Arg Asp Leu Ser Lys Tyr Asn Phe Glu Asn Lys
                 890                 895                 900

 Tyr Gly Thr Arg Ala Leu His Cys Val Leu Thr Thr Ile Leu Ser
                 905                 910                 915

 Gln Thr Glu Asn Lys Val Pro Val Pro Gln Gly Tyr Pro Gly Gly
                 920                 925                 930

 Val Pro Thr Phe Phe Arg Asp Met Lys Gln Gly Leu Leu Ser Val
                 935                 940                 945

 Gly Ile Gly Gly Arg Glu Ser Arg Asn Gly Cys Leu Asp Val Glu
                 950                 955                 960

 Lys Asp Cys Ser Ile Thr Lys Phe Leu Asn Arg Ile Leu Gly Leu
                 965                 970                 975

 Glu Val His Lys Gln Asn Ala Leu Phe Gln Tyr Phe Ser Asp Thr
                 980                 985                 990

 Phe Asp His Leu Ile Glu Met Asp Lys Arg Glu Gly Lys Tyr Asp
                 995                1000                1005

 Met Gly Ile Leu Asp Leu Ala Pro Gly Ile Glu Glu Ile Tyr Glu
                1010                1015                1020

 Glu Ser Gln Gln Val Phe Leu Ala Pro Gly His Pro Gln Asp Gly
                1025                1030                1035

 Gln Val Val Phe Tyr Lys Ile Ser Val Asp Arg Gly Leu Lys Trp
                1040                1045                1050

 Glu Asp Ala Phe Ala Lys Ser Leu Ala Leu Thr Gly Pro Tyr Asp
                1055                1060                1065

 Gly Phe Tyr Leu Ser Tyr Lys Val Arg Gly Asn Lys Pro Ser Cys
                1070                1075                1080

 Leu Leu Ala Glu Gln Asn Arg Gly Gln Phe Phe Thr Val Tyr Lys
                1085                1090                1095

 Pro Asn Ile Gly Arg Gln Ser Gln Leu Glu Ala Leu Asp Ser Leu
                1100                1105                1110

 Arg Arg Lys Phe His Arg Val Thr Ala Glu Glu Ala Lys Glu Pro
                1115                1120                1125

 Trp Glu Ser Gly Tyr Ala Leu Ser Leu Thr His Cys Ser His Ser
                1130                1135                1140

 Ala Trp Asn Arg His Cys Arg Leu Ala Gln Glu Gly Lys Asp Cys
                1145                1150                1155

 Leu Gln Gly Leu Arg Leu Arg His His Tyr Met Leu Cys Gly Ala
                1160                1165                1170

 Leu Leu Arg Val Trp Gly Arg Ile Ala Ala Val Met Ala Asp Val
                1175                1180                1185

 Ser Ser Ser Ser Tyr Leu Gln Ile Val Arg Leu Lys Thr Lys Asp
                1190                1195                1200

 Arg Lys Lys Gln Val Gly Ile Lys Ile Pro Glu Gly Cys Val Arg
                1205                1210                1215

 Arg Val Leu Gln Glu Leu Arg Leu Met Asp Ala Asp Val Lys Arg
                1220                1225                1230

 Arg Gln Ala Pro Ala Leu Gly Cys Pro Ala Pro Pro Ala Pro Arg
                1235                1240                1245

 Pro Leu Ala Leu Pro Cys Gly Pro Gly Glu Val Leu Asp Leu Thr
                1250                1255                1260

 Tyr Ser Pro Pro Ala Glu Ala Phe Pro Pro Pro Pro His Phe Ser
                1265                1270                1275

 Phe Pro Ala Pro Leu Ser Leu Asp Ala Gly Pro Gly Val Val Pro
                1280                1285                1290

 Leu Gly Thr Pro Asp Ala Gln Ala Asp Pro Ala Ala Leu Ala His
                1295                1300                1305

 Gln Gly Cys Asp Ile Asn Phe Lys Glu Val Leu Glu Asp Met Leu
                1310                1315                1320

 Arg Ser Leu His Ala Gly Pro Pro Ser Glu Gly Ala Leu Gly Glu
                1325                1330                1335

 Gly Ala Gly Ala Gly Gly Ala Ala Gly Gly Gly Pro Glu Arg Gln
                1340                1345                1350

 Ser Val Ile Gln Phe Ser Pro Pro Phe Pro Gly Ala Gln Ala Pro
                1355                1360                1365

 Leu


<210> 1081
<211> 627
<212> DNA
<213> Homo sapien

<400> 1081
 agtctccggc gagttgttgc ctgggctgga cgtggttttg tctgctgcgc 50

 ccgctcttcg cgctctcgtt tcattttctg cagcgcgcca cgaggatggc 100

 ccacaagcag atctactact cggacaagta cttcgacgaa cactacgagt 150

 accggcatgt tatgttaccc agagaacttt ccaaacaagt acctaaaact 200

 catctgatgt ctgaagagga gtggaggaga cttggtgtcc aacagagtct 250

 aggctgggtt cattacatga ttcatgagcc agaaccacat attcttctct 300

 ttagacgacc tcttccaaaa gatcaacaaa aatgaagttt atctggggat 350

 cgtcaaatct ttttcaaatt taatgtatat gtgtatataa ggtagtattc 400

 agtgaatact tgagaaatgt acaaatcttt catccatacc tgtgcatgag 450

 ctgtattctt cacagcaaca gagctcagtt aaatgcaact gcaagtaggt 500

 tactgtaaga tgtttaagat aaaagttctt ccagtcagtt tttctcttaa 550

 gtgcctgttt gagtttactg aaacagttta cttttgttca ataaagtttg 600

 tatgttgcat ttaaaaaaaa aaaaaaa 627

<210> 1082
<211> 79
<212> PRT
<213> Homo sapien

<400> 1082
 Met Ala His Lys Gln Ile Tyr Tyr Ser Asp Lys Tyr Phe Asp Glu
   1               5                  10                  15

 His Tyr Glu Tyr Arg His Val Met Leu Pro Arg Glu Leu Ser Lys
                  20                  25                  30

 Gln Val Pro Lys Thr His Leu Met Ser Glu Glu Glu Trp Arg Arg
                  35                  40                  45

 Leu Gly Val Gln Gln Ser Leu Gly Trp Val His Tyr Met Ile His
                  50                  55                  60

 Glu Pro Glu Pro His Ile Leu Leu Phe Arg Arg Pro Leu Pro Lys
                  65                  70                  75

 Asp Gln Gln Lys


<210> 1083
<211> 2691
<212> DNA
<213> Homo sapien

<400> 1083
 ggcacgaggg gggctcaaac gcagggctct gggacgcagg cactgctcca 50

 ggtgatagtg cgggaacatg gccttgcagc tgggcaggct gagctcgggc 100

 ccctgctggc tcgtggcgcg gggcggctgc ggagggcccc gcgcctggtc 150

 ccagtgcggc ggcggagggc tccgagcctg gtcccagcgc agcgcagccg 200

 gacgcgtctg ccggccccct ggcccggctg gcacggagca gagccgcggg 250

 ctggggcacg gctcgacgtc gagaggcggc ccctgggtgg ggacagggct 300

 ggccgcggcg ctggcggggt tggtggggct ggccaccgcc gccttcgggc 350

 atgtgcagcg ggcggagatg ttgcctaaga cctcggggac gcgggccact 400

 tcgctgggga ggccggagga ggaggaggat gagctggccc accgctgcag 450

 cagcttcatg gccccgcctg tgaccgacct gggcgagctg cgaaggaggc 500

 cgggcgacat gaagaccaag atggagctgc tgattctgga gacccaggcc 550

 caggtgtgcc aggctctggc acaggtagac gggggcgcca acttttctgt 600

 ggaccggtgg gagaggaagg aaggaggtgg cggcatcagc tgtgtacttc 650

 aagatgggtg tgttttcgaa aaggctgggg tgagcatttc tgttgttcat 700

 ggaaatcttt cagaggaagc tgcaaaacaa atgagaagca gaggaaaagt 750

 tctgaagact aaagatggta aattgccatt ttgtgctatg ggcgtgagct 800

 ctgttatcca ccccaagaat cctcatgctc ctactatcca tttcaactac 850

 agatactttg aagtagaaga agctgatggc cacaagcagt ggtggtttgg 900

 tggtggatgt gacctcactc caacatactt gaatcaagaa gacgctgtcc 950

 attttcacag aactctgaag gaggcttgtg accagcatgg tccagatctc 1000

 taccccaaat ttaaaaaatg gtgtgatgat tacttcttta tagcccatcg 1050

 tggagagcgg cggggcattg gtggtatctt ttttgatgat cttgactctc 1100

 cgtccaagga ggaggtgttt cgctttgtac agagctgtgc cagggctgta 1150

 gttccttctt acattcccct tgtgaaaaag cactgtgatg actcattcac 1200

 cccccaggag aagctgtggc agcagctcag aagaggacgg tatgtagaat 1250

 ttaatctgct gtatgatcgg ggcacaaagt ttggcctctt cactccagga 1300

 tccagaattg aaagtatctt gatgtcttta cctctaactg cccgatggga 1350

 gtacatgcat tcaccctcag agaattccaa agaagctgaa attctggaag 1400

 ttctacgcca tccaagggac tgggtgcgtt gatgcaggca gaatggctgt 1450

 gcaggggttt ggagggcaca cgatgtgtgc tccccatgcc actggtcggc 1500

 actttgccac tgtgtggcag ttacccgtgc cttagtcttc tccactctgc 1550

 accctacctc gtgggcagat gataacatgt tttggatgct gtcagtgatg 1600

 aatggtgaga tggcagattg tcagagtcaa ttgattaaac ctcatttata 1650

 cttctagtgt cattttatat gactagttta caaaatagga cattgagttt 1700

 ccaagtattg agataaggga atataaatag tattatatgt atcaggaaat 1750

 ctctcatctt gtttttgttt catgtatttt ttaaagtttt catttgtgcc 1800

 acaaaaatct gtcgtggaat atattttatt ttcattaatt cagtgaagtt 1850

 gagacttcat agtaatttta gaatgcaact tgaaggtaaa aattttactt 1900

 tgtcaatact gaagtctctg ctgtaatcct tatatatctt tctccagaga 1950

 acataatatt gtcaaataga tacacatttt tctaataggt atttagaagc 2000

 acttgaaata ttcttaatct ctgcatgtgt tacaattcag ttatttctgt 2050

 agtttgtaaa ctctaaagtg acattactat tattttagag atgtctaagt 2100

 tgtaattttg atttttgtgg aaccattgtt tgttaatgtt gggattctct 2150

 gcacttttga atgtgaaagc ttatatccct gaattctgat acttaagagt 2200

 tttctatttc agacatctct gtgtggaagt tgagactaag aataatccta 2250

 gggatgtcat gaatttaggc aatgtttctc atttggaaaa tgaaatgaga 2300

 aataatttcc ttctttaaag caagtatata tagtatgaga aacttggagg 2350

 catttcatac acacgtttct taggaaaatg gacacattga aaatgtcctc 2400

 tttttttata ttagagattc tgcagctctt tgctcttaag agcaaatcac 2450

 aacaggattc ttaatgtatg atttctttgt tcatatatta tgaatgtatt 2500

 attttatttg cttcgtaata aagtttataa ggaagagcat ctcatacata 2550

 tcattatcgt ggaacacgtt gaatgtttgt gattctgtgt ggcctttttg 2600

 gggctggaaa atgtatgaat tcttcaactg tcttacaaga gatctgctaa 2650

 taaattttat tattaaataa gaaaaaaaaa aaaaaaaaaa a 2691

<210> 1084
<211> 454
<212> PRT
<213> Homo sapien

<400> 1084
 Met Ala Leu Gln Leu Gly Arg Leu Ser Ser Gly Pro Cys Trp Leu
   1               5                  10                  15

 Val Ala Arg Gly Gly Cys Gly Gly Pro Arg Ala Trp Ser Gln Cys
                  20                  25                  30

 Gly Gly Gly Gly Leu Arg Ala Trp Ser Gln Arg Ser Ala Ala Gly
                  35                  40                  45

 Arg Val Cys Arg Pro Pro Gly Pro Ala Gly Thr Glu Gln Ser Arg
                  50                  55                  60

 Gly Leu Gly His Gly Ser Thr Ser Arg Gly Gly Pro Trp Val Gly
                  65                  70                  75

 Thr Gly Leu Ala Ala Ala Leu Ala Gly Leu Val Gly Leu Ala Thr
                  80                  85                  90

 Ala Ala Phe Gly His Val Gln Arg Ala Glu Met Leu Pro Lys Thr
                  95                 100                 105

 Ser Gly Thr Arg Ala Thr Ser Leu Gly Arg Pro Glu Glu Glu Glu
                 110                 115                 120

 Asp Glu Leu Ala His Arg Cys Ser Ser Phe Met Ala Pro Pro Val
                 125                 130                 135

 Thr Asp Leu Gly Glu Leu Arg Arg Arg Pro Gly Asp Met Lys Thr
                 140                 145                 150

 Lys Met Glu Leu Leu Ile Leu Glu Thr Gln Ala Gln Val Cys Gln
                 155                 160                 165

 Ala Leu Ala Gln Val Asp Gly Gly Ala Asn Phe Ser Val Asp Arg
                 170                 175                 180

 Trp Glu Arg Lys Glu Gly Gly Gly Gly Ile Ser Cys Val Leu Gln
                 185                 190                 195

 Asp Gly Cys Val Phe Glu Lys Ala Gly Val Ser Ile Ser Val Val
                 200                 205                 210

 His Gly Asn Leu Ser Glu Glu Ala Ala Lys Gln Met Arg Ser Arg
                 215                 220                 225

 Gly Lys Val Leu Lys Thr Lys Asp Gly Lys Leu Pro Phe Cys Ala
                 230                 235                 240

 Met Gly Val Ser Ser Val Ile His Pro Lys Asn Pro His Ala Pro
                 245                 250                 255

 Thr Ile His Phe Asn Tyr Arg Tyr Phe Glu Val Glu Glu Ala Asp
                 260                 265                 270

 Gly His Lys Gln Trp Trp Phe Gly Gly Gly Cys Asp Leu Thr Pro
                 275                 280                 285

 Thr Tyr Leu Asn Gln Glu Asp Ala Val His Phe His Arg Thr Leu
                 290                 295                 300

 Lys Glu Ala Cys Asp Gln His Gly Pro Asp Leu Tyr Pro Lys Phe
                 305                 310                 315

 Lys Lys Trp Cys Asp Asp Tyr Phe Phe Ile Ala His Arg Gly Glu
                 320                 325                 330

 Arg Arg Gly Ile Gly Gly Ile Phe Phe Asp Asp Leu Asp Ser Pro
                 335                 340                 345

 Ser Lys Glu Glu Val Phe Arg Phe Val Gln Ser Cys Ala Arg Ala
                 350                 355                 360

 Val Val Pro Ser Tyr Ile Pro Leu Val Lys Lys His Cys Asp Asp
                 365                 370                 375

 Ser Phe Thr Pro Gln Glu Lys Leu Trp Gln Gln Leu Arg Arg Gly
                 380                 385                 390

 Arg Tyr Val Glu Phe Asn Leu Leu Tyr Asp Arg Gly Thr Lys Phe
                 395                 400                 405

 Gly Leu Phe Thr Pro Gly Ser Arg Ile Glu Ser Ile Leu Met Ser
                 410                 415                 420

 Leu Pro Leu Thr Ala Arg Trp Glu Tyr Met His Ser Pro Ser Glu
                 425                 430                 435

 Asn Ser Lys Glu Ala Glu Ile Leu Glu Val Leu Arg His Pro Arg
                 440                 445                 450

 Asp Trp Val Arg


<210> 1085
<211> 873
<212> DNA
<213> Homo sapien

<400> 1085
 acttcccctt cctgtacagg gcaggttgtg cagctggagg cagagcagtc 50

 ctctctgggg agcctgaagc aaacatggat caagaaactg taggcaatgt 100

 tgtcctgttg gccatcgtca ccctcatcag cgtggtccag aatggattct 150

 ttgcccataa agtggagcac gaaagcagga cccagaatgg gaggagcttc 200

 cagaggaccg gaacacttgc ctttgagcgg gtctacactg ccaaccagaa 250

 ctgtgtagat gcgtacccca ctttcctcgc tgtgctctgg tctgcggggc 300

 tactttgcag ccaagttcct gctgcgtttg ctggactgat gtacttgttt 350

 gtgaggcaaa agtactttgt cggttaccta ggagagagaa cgcagagcac 400

 ccctggctac atatttggga aacgcatcat actcttcctg ttcctcatgt 450

 ccgttgctgg catattcaac tattacctca tcttcttttt cggaagtgac 500

 tttgaaaact acataaagac gatctccacc accatctccc ctctacttct 550

 cattccctaa ctctctgctg aatatggggt tggtgttctc atctaatcaa 600

 tacctacaag tcatcataat tcagctcttg agagcattct gctcttcttt 650

 agatggctgt aaatctattg gccatctggg cttcacagct tgagttaacc 700

 ttgcttttcc gggaacaaaa tgatgtcatg tcagctccgc cccttgaaca 750

 tgaccgtggc cccaaatttg ctattcccat gcattttgtt tgtttcttca 800

 cttatcctgt tctctgaaga tgttttgtga ccaggtttgt gttttcttaa 850

 aataaaatgc agagacatgt ttt 873

<210> 1086
<211> 161
<212> PRT
<213> Homo sapien

<400> 1086
 Met Asp Gln Glu Thr Val Gly Asn Val Val Leu Leu Ala Ile Val
   1               5                  10                  15

 Thr Leu Ile Ser Val Val Gln Asn Gly Phe Phe Ala His Lys Val
                  20                  25                  30

 Glu His Glu Ser Arg Thr Gln Asn Gly Arg Ser Phe Gln Arg Thr
                  35                  40                  45

 Gly Thr Leu Ala Phe Glu Arg Val Tyr Thr Ala Asn Gln Asn Cys
                  50                  55                  60

 Val Asp Ala Tyr Pro Thr Phe Leu Ala Val Leu Trp Ser Ala Gly
                  65                  70                  75

 Leu Leu Cys Ser Gln Val Pro Ala Ala Phe Ala Gly Leu Met Tyr
                  80                  85                  90

 Leu Phe Val Arg Gln Lys Tyr Phe Val Gly Tyr Leu Gly Glu Arg
                  95                 100                 105

 Thr Gln Ser Thr Pro Gly Tyr Ile Phe Gly Lys Arg Ile Ile Leu
                 110                 115                 120

 Phe Leu Phe Leu Met Ser Val Ala Gly Ile Phe Asn Tyr Tyr Leu
                 125                 130                 135

 Ile Phe Phe Phe Gly Ser Asp Phe Glu Asn Tyr Ile Lys Thr Ile
                 140                 145                 150

 Ser Thr Thr Ile Ser Pro Leu Leu Leu Ile Pro
                 155                 160

<210> 1087
<211> 1125
<212> DNA
<213> Homo sapien

<400> 1087
 gtctccccca ctgtcagcac ctcttctgtg tggtgagtgg accgcttacc 50

 ccactaggtg aagatgtcag cccaggagag ctgcctcagc ctcatcaagt 100

 acttcctctt cgttttcaac ctcttcttct tcgtcctcgg cagcctgatc 150

 ttctgcttcg gcatctggat cctcatcgac aagaccagct tcgtgtcctt 200

 tgtgggcttg gccttcgtgc ctctgcagat ctggtccaaa gtcctggcca 250

 tctcaggaat cttcaccatg ggcatcgccc tcctgggttg tgtgggggcc 300

 ctcaaggagc tccgctgcct cctgggcctg tattttggga tgctgctgct 350

 cctgtttgcc acacagatca ccctgggaat cctcatctcc actcagcggg 400

 cccagctgga gcgaagcttg cgggacgtcg tagagaaaac catccaaaag 450

 tacggcacca accccgagga gaccgcggcc gaggagagct gggactatgt 500

 gcagttccag ctgcgctgct gcggctggca ctacccgcag gactggttcc 550

 aagtcctcat cctgagaggt aacgggtcgg aggcgcaccg cgtgccctgc 600

 tcctgctaca acttgtcggc gaccaacgac tccacaatcc tagataaggt 650

 gatcttgccc cagctcagca ggcttggaca cctggcgcgg tccagacaca 700

 gtgcagacat ctgcgctgtc cctgcagaga gccacatcta ccgcgagggc 750

 tgcgcgcagg gcctccagaa gtggctgcac aacaacctta tttccatagt 800

 gggcatttgc ctgggcgtcg gcctactcga gctcgggttc atgacgctct 850

 cgatattcct gtgcagaaac ctggaccacg tctacaaccg gctcgctcga 900

 taccgttagg ccccgccctc cccaaagtcc cgccccgccc ccgtcacgtg 950

 cgctgggcac ttccctgctg cctgtaaata tttgtttaat ccccagttcg 1000

 cctggagccc tccgccttca cattcccctg gggacccacg tggctgcgtg 1050

 cccctgctgc tgtcacctct cccacgggac ctggggcttt cgtccacagc 1100

 ttcctgtccc catctgtcgg cctac 1125

<210> 1088
<211> 281
<212> PRT
<213> Homo sapien

<400> 1088
 Met Ser Ala Gln Glu Ser Cys Leu Ser Leu Ile Lys Tyr Phe Leu
   1               5                  10                  15

 Phe Val Phe Asn Leu Phe Phe Phe Val Leu Gly Ser Leu Ile Phe
                  20                  25                  30

 Cys Phe Gly Ile Trp Ile Leu Ile Asp Lys Thr Ser Phe Val Ser
                  35                  40                  45

 Phe Val Gly Leu Ala Phe Val Pro Leu Gln Ile Trp Ser Lys Val
                  50                  55                  60

 Leu Ala Ile Ser Gly Ile Phe Thr Met Gly Ile Ala Leu Leu Gly
                  65                  70                  75

 Cys Val Gly Ala Leu Lys Glu Leu Arg Cys Leu Leu Gly Leu Tyr
                  80                  85                  90

 Phe Gly Met Leu Leu Leu Leu Phe Ala Thr Gln Ile Thr Leu Gly
                  95                 100                 105

 Ile Leu Ile Ser Thr Gln Arg Ala Gln Leu Glu Arg Ser Leu Arg
                 110                 115                 120

 Asp Val Val Glu Lys Thr Ile Gln Lys Tyr Gly Thr Asn Pro Glu
                 125                 130                 135

 Glu Thr Ala Ala Glu Glu Ser Trp Asp Tyr Val Gln Phe Gln Leu
                 140                 145                 150

 Arg Cys Cys Gly Trp His Tyr Pro Gln Asp Trp Phe Gln Val Leu
                 155                 160                 165

 Ile Leu Arg Gly Asn Gly Ser Glu Ala His Arg Val Pro Cys Ser
                 170                 175                 180

 Cys Tyr Asn Leu Ser Ala Thr Asn Asp Ser Thr Ile Leu Asp Lys
                 185                 190                 195

 Val Ile Leu Pro Gln Leu Ser Arg Leu Gly His Leu Ala Arg Ser
                 200                 205                 210

 Arg His Ser Ala Asp Ile Cys Ala Val Pro Ala Glu Ser His Ile
                 215                 220                 225

 Tyr Arg Glu Gly Cys Ala Gln Gly Leu Gln Lys Trp Leu His Asn
                 230                 235                 240

 Asn Leu Ile Ser Ile Val Gly Ile Cys Leu Gly Val Gly Leu Leu
                 245                 250                 255

 Glu Leu Gly Phe Met Thr Leu Ser Ile Phe Leu Cys Arg Asn Leu
                 260                 265                 270

 Asp His Val Tyr Asn Arg Leu Ala Arg Tyr Arg
                 275                 280

<210> 1089
<211> 3809
<212> DNA
<213> Homo sapien

<400> 1089
 gccgctgtta tgcgtattcc cgtagaccca agcaccagcc gccgcttcac 50

 acctccctcc ccggccttcc cctgcggcgg cggcggcggc aagatgggcg 100

 agaacagcgg cgcgctgagc gcgcaggcgg ccgtggggcc cggagggcgc 150

 gcccggcccg aggtgcgctc gatggtggac gtgctggcgg accacgcagg 200

 cgagctcgtg cgcaccgaca gccccaactt cctctgctcc gtgctgccct 250

 cgcactggcg ctgcaacaag acgctgcccg tcgccttcaa ggtggtggca 300

 ttgggggacg tgccggatgg tacggtggtg actgtgatgg caggcaatga 350

 cgagaactac tccgctgagc tgcgcaatgc ctcggccgtc atgaagaacc 400

 aggtggccag gttcaacgac cttcgcttcg tgggccgcag tgggcgaggg 450

 aagagtttca ccctgaccat cactgtgttc accaacccca cccaagtggc 500

 gacctaccac cgagccatca aggtgaccgt ggacggaccc cgggagccca 550

 gacggcaccg gcagaagctg gaggaccaga ccaagccgtt ccctgaccgc 600

 tttggggacc tggaacggct gcgcatgcgg gtgacaccga gcacacccag 650

 cccccgaggc tcactcagca ccacaagcca cttcagcagc cagccccaga 700

 ccccaatcca aggcacctcg gaactgaacc cattctccga cccccgccag 750

 tttgaccgct ccttccccac gctgccaacc ctcacggaga gccgcttccc 800

 agaccccagg atgcattatc ccggggccat gtcagctgcc ttcccctaca 850

 gcgccacgcc ctcgggcacg agcatcagca gcctcagcgt ggcgggcatg 900

 ccggccacca gccgcttcca ccatacctac ctcccgccac cctacccggg 950

 ggccccgcag aaccagagcg ggcccttcca ggccaacccg tccccctacc 1000

 acctctacta cgggacatcc tctggctcct accagttctc catggtggcc 1050

 ggcagcagca gtgggggcga ccgctcacct acccgcatgc tggcctcttg 1100

 caccagcagc gctgcctctg tcgccgccgg caacctcatg aaccccagcc 1150

 tgggcggcca gagtgatggc gtggaggccg acggcagcca cagcaactca 1200

 cccacggccc tgagcacgcc aggccgcatg gatgaggccg tgtggcggcc 1250

 ctactgaccg ccctggtgga ctcctcccgc tggaggcggg gaccctaaca 1300

 accttcaaga ccagtgatgg gccggctccg aggctccggg cgggaatggg 1350

 acctgcgctc cagggtggtc tcggtcccag ggtggtccca gctggtggga 1400

 gcctctggct gcatctgtgc agccacatcc ttgtacagag gcataggtta 1450

 ccacccccac cccggcccgg gatactgccc ccggcccaga tcctggccgt 1500

 ctcatcccat acttctgtgg ggaatcagcc tcctgccacc cccccggaag 1550

 gacctcactg tctccagcta tgcccagtgc tgcatgggac ccatgtctcc 1600

 tgggacagag gccatctctc ttccagagag aggcagcatt ggcccacagg 1650

 ataagcctca ggccctggga aacctcccga cccctgcacc ttcgttggag 1700

 cccctgcatc ccctgggtcc agccccctct gcatttacac agatttgagt 1750

 cagaactgga aagtgtcccc cacccccacc accctcgagc ggggttcccc 1800

 tcattgtaca gatggggcag gacccagcac gctgctggca gagatggttt 1850

 gagaacacat ccaagccagt ccccccagcc cagcttcccc tccgttccta 1900

 actgttggct ttcccccagc cgcacggtcc caggcccaga gaagatgagt 1950

 ctatggcatc aggttcttaa accaggaaag cacctacaga ccggctcctc 2000

 catgcacttt accagctcaa cgcatccact ctctgttctc ttggcagggc 2050

 gggggagggg ggataggagg tcccctttcc cctaggtggt ctcataattc 2100

 catttgtgga gagaacagga gggccagata gataggtcct agcagaaggc 2150

 attgaggtga gggatcattt tgggtcagac atcaatgtcc ctgtcccccc 2200

 tgggtccagc caagctgtgc cccatccccc aagcctcctg ggaggatcca 2250

 gccaaatctt gcgactcctg gcacacacct gtctgtaacc tgttttgtgc 2300

 tctgaaagca aatagtcctg agcaaaaaaa aaaaaaaaaa acaaaaaaac 2350

 aaaaaaaaaa caaaacagtt tttaaaactg attttagaaa aagaagctta 2400

 atctaacgtt ttcaaacaca aggtctctta caggtatagt tccgtgatta 2450

 tgatagctct gtgattataa gcaacatccc cgccccctct cccccccgcg 2500

 gacccccagc tgcctcctga gggtgtgggg ttattagggt ctcaatactt 2550

 tctcaagggg ctacactccc catcaggcag catcccacca gcctgcacca 2600

 caggctcccc tgggaggacg agggaaacgc tgatgagacg ctgggcatct 2650

 ctcctctgtg gctctaggac atctgtccag gaggctgggc ggaggtgggc 2700

 aggatgtgag aggtggggag tactggctgt gcgtggcagg acagaagcac 2750

 tgtaaagggc tctccagcgc agctcagctg cactgcgttc cgaggtgaag 2800

 tcttgcccct gaattttgca aaatgggaaa gtgggcgctt gccaagggcc 2850

 aggctgcatg gattctcaca tcagagttct ctggccctag aaaggcttag 2900

 aaaaggcgta agggaactca taaaggctag cagcatgcgg tattttaact 2950

 ttctgcctcg gcctctgtgg atgcagaaat ctgccctaca aaatgctctt 3000

 cattggttgt ctctgtgaga gcactgtccc cacccaacct gtcacaacgg 3050

 ccagaaccat acaccagaga cacactggca ggttaggcag tccttctggt 3100

 gatcctattc cattccctcc tgctgcggtt tctcttggcc tgtcctcact 3150

 ggaaaaacag tctccatctc ctcaaaatag ttgctgactc cctgcaccca 3200

 aggggcctct ccatgccttc ttaggaagca gctatgaatc cattgtcctt 3250

 gtagtttctt ccctcctgtt ctctggttat agctggtccc aggtcagcgt 3300

 gggaggcacc tttgggttcc cagtgcccag cactttgtag tctcatccca 3350

 gattactaac ccttcctgat cctggagagg cagggatagt aaataaattg 3400

 ctcttcctac cccatccccc atcccctgac aaaaagtgac ggcagccgta 3450

 ctgagtctgt aaggcccaaa gtgggtacag acagcctggg ctggtaaaag 3500

 taggtcctta tttacaaggc tgcgttaaag ttgtactagg caaacacact 3550

 gatgtaggaa gcacgaggaa aggaagacgt tttgatatag tgttactgtg 3600

 agcctgtcag tagtgggtac caatcttttg tgacatattg tcatgctgag 3650

 gtgtgacacc tgctgcactc atctgatgta aaaccatccc agagctggcg 3700

 agaggatgga gctgggtgga aactgctttg cactatcgtt tgcttggtgt 3750

 ttgtttttaa cgcacaactt gcttgtacag taaactgtct tctgtactat 3800

 ttaactgta 3809

<210> 1090
<211> 415
<212> PRT
<213> Homo sapien

<400> 1090
 Met Arg Ile Pro Val Asp Pro Ser Thr Ser Arg Arg Phe Thr Pro
   1               5                  10                  15

 Pro Ser Pro Ala Phe Pro Cys Gly Gly Gly Gly Gly Lys Met Gly
                  20                  25                  30

 Glu Asn Ser Gly Ala Leu Ser Ala Gln Ala Ala Val Gly Pro Gly
                  35                  40                  45

 Gly Arg Ala Arg Pro Glu Val Arg Ser Met Val Asp Val Leu Ala
                  50                  55                  60

 Asp His Ala Gly Glu Leu Val Arg Thr Asp Ser Pro Asn Phe Leu
                  65                  70                  75

 Cys Ser Val Leu Pro Ser His Trp Arg Cys Asn Lys Thr Leu Pro
                  80                  85                  90

 Val Ala Phe Lys Val Val Ala Leu Gly Asp Val Pro Asp Gly Thr
                  95                 100                 105

 Val Val Thr Val Met Ala Gly Asn Asp Glu Asn Tyr Ser Ala Glu
                 110                 115                 120

 Leu Arg Asn Ala Ser Ala Val Met Lys Asn Gln Val Ala Arg Phe
                 125                 130                 135

 Asn Asp Leu Arg Phe Val Gly Arg Ser Gly Arg Gly Lys Ser Phe
                 140                 145                 150

 Thr Leu Thr Ile Thr Val Phe Thr Asn Pro Thr Gln Val Ala Thr
                 155                 160                 165

 Tyr His Arg Ala Ile Lys Val Thr Val Asp Gly Pro Arg Glu Pro
                 170                 175                 180

 Arg Arg His Arg Gln Lys Leu Glu Asp Gln Thr Lys Pro Phe Pro
                 185                 190                 195

 Asp Arg Phe Gly Asp Leu Glu Arg Leu Arg Met Arg Val Thr Pro
                 200                 205                 210

 Ser Thr Pro Ser Pro Arg Gly Ser Leu Ser Thr Thr Ser His Phe
                 215                 220                 225

 Ser Ser Gln Pro Gln Thr Pro Ile Gln Gly Thr Ser Glu Leu Asn
                 230                 235                 240

 Pro Phe Ser Asp Pro Arg Gln Phe Asp Arg Ser Phe Pro Thr Leu
                 245                 250                 255

 Pro Thr Leu Thr Glu Ser Arg Phe Pro Asp Pro Arg Met His Tyr
                 260                 265                 270

 Pro Gly Ala Met Ser Ala Ala Phe Pro Tyr Ser Ala Thr Pro Ser
                 275                 280                 285

 Gly Thr Ser Ile Ser Ser Leu Ser Val Ala Gly Met Pro Ala Thr
                 290                 295                 300

 Ser Arg Phe His His Thr Tyr Leu Pro Pro Pro Tyr Pro Gly Ala
                 305                 310                 315

 Pro Gln Asn Gln Ser Gly Pro Phe Gln Ala Asn Pro Ser Pro Tyr
                 320                 325                 330

 His Leu Tyr Tyr Gly Thr Ser Ser Gly Ser Tyr Gln Phe Ser Met
                 335                 340                 345

 Val Ala Gly Ser Ser Ser Gly Gly Asp Arg Ser Pro Thr Arg Met
                 350                 355                 360

 Leu Ala Ser Cys Thr Ser Ser Ala Ala Ser Val Ala Ala Gly Asn
                 365                 370                 375

 Leu Met Asn Pro Ser Leu Gly Gly Gln Ser Asp Gly Val Glu Ala
                 380                 385                 390

 Asp Gly Ser His Ser Asn Ser Pro Thr Ala Leu Ser Thr Pro Gly
                 395                 400                 405

 Arg Met Asp Glu Ala Val Trp Arg Pro Tyr
                 410                 415

<210> 1091
<211> 1001
<212> DNA
<213> Homo sapien

<400> 1091
 gccgcggctg cggaacgggc ggaggctgcc ggtttcgtaa ccgtcgctcc 50

 tcctcgctga ctcgcgggct gtgaggcctg ggtcggctcg ggccgcaccg 100

 cgcggggccg ctcggagtgg aggccgcctg ggggcaggcg ggctagagga 150

 gcaggtacat gtgaagattt tttggcagct tagcgtggaa accattgatc 200

 accctgctct catttctacc tgttctgtgt tggcaaggga gagtgcccaa 250

 atgagcaaga tatcgcagca aaacagcact ccaggggtga acggaattag 300

 tgttatccat acccaggcac atgccagcgg cttacagcag gttcctcagc 350

 tggtgcctgc tggccctggg ggaggaggca aagctgtggc tcccagcaag 400

 cagagcaaaa agagttcgcc catggatcga aacagtgacg agtatcggca 450

 acgccgagag aggaacaaca tggctgtgaa aaagagccgg ttgaaaagca 500

 agcagaaagc acaagacaca ctgcagagag tcaatcagct caaagaagag 550

 aatgaacggt tggaagcaaa aatcaaattg ctgaccaagg aattaagtgt 600

 actcaaagat ttgtttcttg agcatgcaca caaccttgca gacaacgtac 650

 agtccattag cactgaaaat acgacagcag atggcgacaa tgcaggacag 700

 tagacctcac cctttccaga ctttagagct tgtggcttga atgttaaagg 750

 tgtgaccacc gacaccactc atgtcaatgg ctgaaagttg tccatttcca 800

 tgactcaaag acccattgga ggctattttc tgggatcagc actgaagagt 850

 tgattagcta aaaatgttag ccttgtaatt cgaatatctg gttttaaatg 900

 atagaggttt ttgtgggaat caaaatcccc caaatgttaa ggtatatggt 950

 aaaaaaagaa atatctggga tcccgatgtt cttaataaat cctgacttcc 1000

 c 1001

<210> 1092
<211> 150
<212> PRT
<213> Homo sapien

<400> 1092
 Met Ser Lys Ile Ser Gln Gln Asn Ser Thr Pro Gly Val Asn Gly
   1               5                  10                  15

 Ile Ser Val Ile His Thr Gln Ala His Ala Ser Gly Leu Gln Gln
                  20                  25                  30

 Val Pro Gln Leu Val Pro Ala Gly Pro Gly Gly Gly Gly Lys Ala
                  35                  40                  45

 Val Ala Pro Ser Lys Gln Ser Lys Lys Ser Ser Pro Met Asp Arg
                  50                  55                  60

 Asn Ser Asp Glu Tyr Arg Gln Arg Arg Glu Arg Asn Asn Met Ala
                  65                  70                  75

 Val Lys Lys Ser Arg Leu Lys Ser Lys Gln Lys Ala Gln Asp Thr
                  80                  85                  90

 Leu Gln Arg Val Asn Gln Leu Lys Glu Glu Asn Glu Arg Leu Glu
                  95                 100                 105

 Ala Lys Ile Lys Leu Leu Thr Lys Glu Leu Ser Val Leu Lys Asp
                 110                 115                 120

 Leu Phe Leu Glu His Ala His Asn Leu Ala Asp Asn Val Gln Ser
                 125                 130                 135

 Ile Ser Thr Glu Asn Thr Thr Ala Asp Gly Asp Asn Ala Gly Gln
                 140                 145                 150

<210> 1093
<211> 1717
<212> DNA
<213> Homo sapien

<400> 1093
 ctgccagggg gagggcccca gagaaaacca gaaagagggt gagagactga 50

 ggaagataaa gcgtcccagg gcctcctaca ccagcgcctg agcaggaagc 100

 gggaggggcc atgactacga ggccctggga ggtcacttta gggagggctg 150

 tcctaaaacc agaagcttgg agcagaaagt gaaaccctgg tgctccagac 200

 aaagatctta gtcgggacta gccggccaag gatgaagcct cacttcagaa 250

 acacagtgga gcgaatgtat cgagacacat tctcctacaa cttttataat 300

 agacccatcc tttctcgtcg gaataccgtc tggctgtgct acgaagtgaa 350

 aacaaagggt ccctcaaggc cccctttgga cgcaaagatc tttcgaggcc 400

 aggtgtattc cgaacttaag taccacccag agatgagatt cttccactgg 450

 ttcagcaagt ggaggaagct gcatcgtgac caggagtatg aggtcacctg 500

 gtacatatcc tggagcccct gcacaaagtg tacaagggat atggccacgt 550

 tcctggccga ggacccgaag gttaccctga ccatcttcgt tgcccgcctc 600

 tactacttct gggacccaga ttaccaggag gcgcttcgca gcctgtgtca 650

 gaaaagagac ggtccgcgtg ccaccatgaa gatcatgaat tatgacgaat 700

 ttcagcactg ttggagcaag ttcgtgtaca gccaaagaga gctatttgag 750

 ccttggaata atctgcctaa atattatata ttactgcaca tcatgctggg 800

 ggagattctc agacactcga tggatccacc cacattcact ttcaacttta 850

 acaatgaacc ttgggtcaga ggacggcatg agacttacct gtgttatgag 900

 gtggagcgca tgcacaatga cacctgggtc ctgctgaacc agcgcagggg 950

 ctttctatgc aaccaggctc cacataaaca cggtttcctt gaaggccgcc 1000

 atgcagagct gtgcttcctg gacgtgattc ccttttggaa gctggacctg 1050

 gaccaggact acagggttac ctgcttcacc tcctggagcc cctgcttcag 1100

 ctgtgcccag gaaatggcta aattcatttc aaaaaacaaa cacgtgagcc 1150

 tgtgcatctt cactgcccgc atctatgatg atcaaggaag atgtcaggag 1200

 gggctgcgca ccctggccga ggctggggcc aaaatttcaa taatgacata 1250

 cagtgaattt aagcactgct gggacacctt tgtggaccac cagggatgtc 1300

 ccttccagcc ctgggatgga ctagatgagc acagccaaga cctgagtggg 1350

 aggctgcggg ccattctcca gaatcaggaa aactgaagga tgggcctcag 1400

 tctctaagga aggcagagac ctgggttgag cctcagaata aaagatcttc 1450

 ttccaagaaa tgcaaacagg ctgttcacca ccatctccag ctgatcacag 1500

 acaccagcaa agcaatgcac tcctgaccaa gtagattctt ttaaaaatta 1550

 gagtgcatta ctttgaatca aaaatttatt tatatttcaa gaataaagta 1600

 ctaagattgt gctcaataca cagaaaagtt tcaaacctac taatccagcg 1650

 acaatttgaa tcggttttgt aggtagagga ataaaatgaa atactaaatc 1700

 tttctgtaaa aaaaaaa 1717

<210> 1094
<211> 384
<212> PRT
<213> Homo sapien

<400> 1094
 Met Lys Pro His Phe Arg Asn Thr Val Glu Arg Met Tyr Arg Asp
   1               5                  10                  15

 Thr Phe Ser Tyr Asn Phe Tyr Asn Arg Pro Ile Leu Ser Arg Arg
                  20                  25                  30

 Asn Thr Val Trp Leu Cys Tyr Glu Val Lys Thr Lys Gly Pro Ser
                  35                  40                  45

 Arg Pro Pro Leu Asp Ala Lys Ile Phe Arg Gly Gln Val Tyr Ser
                  50                  55                  60

 Glu Leu Lys Tyr His Pro Glu Met Arg Phe Phe His Trp Phe Ser
                  65                  70                  75

 Lys Trp Arg Lys Leu His Arg Asp Gln Glu Tyr Glu Val Thr Trp
                  80                  85                  90

 Tyr Ile Ser Trp Ser Pro Cys Thr Lys Cys Thr Arg Asp Met Ala
                  95                 100                 105

 Thr Phe Leu Ala Glu Asp Pro Lys Val Thr Leu Thr Ile Phe Val
                 110                 115                 120

 Ala Arg Leu Tyr Tyr Phe Trp Asp Pro Asp Tyr Gln Glu Ala Leu
                 125                 130                 135

 Arg Ser Leu Cys Gln Lys Arg Asp Gly Pro Arg Ala Thr Met Lys
                 140                 145                 150

 Ile Met Asn Tyr Asp Glu Phe Gln His Cys Trp Ser Lys Phe Val
                 155                 160                 165

 Tyr Ser Gln Arg Glu Leu Phe Glu Pro Trp Asn Asn Leu Pro Lys
                 170                 175                 180

 Tyr Tyr Ile Leu Leu His Ile Met Leu Gly Glu Ile Leu Arg His
                 185                 190                 195

 Ser Met Asp Pro Pro Thr Phe Thr Phe Asn Phe Asn Asn Glu Pro
                 200                 205                 210

 Trp Val Arg Gly Arg His Glu Thr Tyr Leu Cys Tyr Glu Val Glu
                 215                 220                 225

 Arg Met His Asn Asp Thr Trp Val Leu Leu Asn Gln Arg Arg Gly
                 230                 235                 240

 Phe Leu Cys Asn Gln Ala Pro His Lys His Gly Phe Leu Glu Gly
                 245                 250                 255

 Arg His Ala Glu Leu Cys Phe Leu Asp Val Ile Pro Phe Trp Lys
                 260                 265                 270

 Leu Asp Leu Asp Gln Asp Tyr Arg Val Thr Cys Phe Thr Ser Trp
                 275                 280                 285

 Ser Pro Cys Phe Ser Cys Ala Gln Glu Met Ala Lys Phe Ile Ser
                 290                 295                 300

 Lys Asn Lys His Val Ser Leu Cys Ile Phe Thr Ala Arg Ile Tyr
                 305                 310                 315

 Asp Asp Gln Gly Arg Cys Gln Glu Gly Leu Arg Thr Leu Ala Glu
                 320                 325                 330

 Ala Gly Ala Lys Ile Ser Ile Met Thr Tyr Ser Glu Phe Lys His
                 335                 340                 345

 Cys Trp Asp Thr Phe Val Asp His Gln Gly Cys Pro Phe Gln Pro
                 350                 355                 360

 Trp Asp Gly Leu Asp Glu His Ser Gln Asp Leu Ser Gly Arg Leu
                 365                 370                 375

 Arg Ala Ile Leu Gln Asn Gln Glu Asn
                 380

<210> 1095
<211> 561
<212> DNA
<213> Homo sapien

<400> 1095
 aatcatgtct gactccctgg tggtgtgcga ggtagaccca gagctaacag 50

 aaaagctgag gaaattccgc ttccgaaaag agacagacaa tgcagccatc 100

 ataatgaagg tggacaaaga ccggcagatg gtggtgctgg aggaagaatt 150

 tcagaacatt tccccagagg agctcaaaat ggagttgccg gagagacagc 200

 ccaggttcgt ggtttacagc tacaagtacg tgcatgacga tggccgagtg 250

 tcctaccctt tgtgtttcat cttctccagc cctgtgggct gcaagccgga 300

 acaacagatg atgtatgcag ggagtaaaaa caggctggtg cagacagcag 350

 agctcacaaa ggtgttcgaa atccgcacca ctgatgacct cactgaggcc 400

 tggctccaag aaaagttgtc tttctttcgt tgatctctgg gctggggact 450

 gaattcctga tgtctgagtc ctcaggtgac tggggacttg gaaccctagg 500

 acctgaacaa ccaagacttt aaataatttt aaatgcaaaa actcagaaaa 550

 aaaaaaaaaa a 561

<210> 1096
<211> 142
<212> PRT
<213> Homo sapien

<400> 1096
 Met Ser Asp Ser Leu Val Val Cys Glu Val Asp Pro Glu Leu Thr
   1               5                  10                  15

 Glu Lys Leu Arg Lys Phe Arg Phe Arg Lys Glu Thr Asp Asn Ala
                  20                  25                  30

 Ala Ile Ile Met Lys Val Asp Lys Asp Arg Gln Met Val Val Leu
                  35                  40                  45

 Glu Glu Glu Phe Gln Asn Ile Ser Pro Glu Glu Leu Lys Met Glu
                  50                  55                  60

 Leu Pro Glu Arg Gln Pro Arg Phe Val Val Tyr Ser Tyr Lys Tyr
                  65                  70                  75

 Val His Asp Asp Gly Arg Val Ser Tyr Pro Leu Cys Phe Ile Phe
                  80                  85                  90

 Ser Ser Pro Val Gly Cys Lys Pro Glu Gln Gln Met Met Tyr Ala
                  95                 100                 105

 Gly Ser Lys Asn Arg Leu Val Gln Thr Ala Glu Leu Thr Lys Val
                 110                 115                 120

 Phe Glu Ile Arg Thr Thr Asp Asp Leu Thr Glu Ala Trp Leu Gln
                 125                 130                 135

 Glu Lys Leu Ser Phe Phe Arg
                 140

<210> 1097
<211> 1061
<212> DNA
<213> Homo sapien

<400> 1097
 ctctgttttc tcaaagctga agtcggctag gtttgcaaag ctgtgggctg 50

 agcactcagg caatcacact ctcagaaact gcggcggctc tggactgcag 100

 cctcccaagg ctccatgcca gacaaagcat gcgtgtcaca cttgctacaa 150

 tagcctggat ggtttctttt gtctccaatt attcacacac agcaaatatt 200

 ttgccagata tcgaaaatga agatttcatc aaagactgcg ttcgaatcca 250

 taacaagttc cgatcagagg tgaaaccaac agccagtgat atgctataca 300

 tgacttggga cccagcacta gcccaaattg caaaagcatg ggccagcaat 350

 tgccagtttt cacataatac acggctgaag ccaccccaca agctgcaccc 400

 aaacttcact tcactgggag agaacatctg gactgggtct gtgcccattt 450

 tttctgtgtc ttccgccatc acaaactggt atgacgaaat ccaggactat 500

 gacttcaaga ctcggatatg caaaaaagtc tgtggccact acactcaggt 550

 tgtttgggca gatagttaca aagttggctg cgcagttcaa ttttgcccta 600

 aagtttctgg ctttgacgct ctttccaatg gagcacattt tatatgcaac 650

 tacggaccag gagggaatta cccaacttgg ccatataaga gaggagccac 700

 ctgcagtgcc tgccccaata atgacaagtg tttggacaat ctctgtgtta 750

 accgacagcg agaccaagtg aaacgttact actctgttgt atatccaggc 800

 tggcccatat atccacgtaa cagatacact tctctctttc tcattgttaa 850

 ttcagtaatt ctaatactgt ctgttataat taccattttg gtacagctca 900

 agtaccctaa tttagttctt ttggactaat acaattcagg aaagaaaaaa 950

 cccaaaaacc aacctcattc acatatggct tttttttaac caataacaat 1000

 taggtgtact tctattttaa aacatttcag aaaaaaatat atgttatagc 1050

 aatactctta c 1061

<210> 1098
<211> 266
<212> PRT
<213> Homo sapien

<400> 1098
 Met Arg Val Thr Leu Ala Thr Ile Ala Trp Met Val Ser Phe Val
   1               5                  10                  15

 Ser Asn Tyr Ser His Thr Ala Asn Ile Leu Pro Asp Ile Glu Asn
                  20                  25                  30

 Glu Asp Phe Ile Lys Asp Cys Val Arg Ile His Asn Lys Phe Arg
                  35                  40                  45

 Ser Glu Val Lys Pro Thr Ala Ser Asp Met Leu Tyr Met Thr Trp
                  50                  55                  60

 Asp Pro Ala Leu Ala Gln Ile Ala Lys Ala Trp Ala Ser Asn Cys
                  65                  70                  75

 Gln Phe Ser His Asn Thr Arg Leu Lys Pro Pro His Lys Leu His
                  80                  85                  90

 Pro Asn Phe Thr Ser Leu Gly Glu Asn Ile Trp Thr Gly Ser Val
                  95                 100                 105

 Pro Ile Phe Ser Val Ser Ser Ala Ile Thr Asn Trp Tyr Asp Glu
                 110                 115                 120

 Ile Gln Asp Tyr Asp Phe Lys Thr Arg Ile Cys Lys Lys Val Cys
                 125                 130                 135

 Gly His Tyr Thr Gln Val Val Trp Ala Asp Ser Tyr Lys Val Gly
                 140                 145                 150

 Cys Ala Val Gln Phe Cys Pro Lys Val Ser Gly Phe Asp Ala Leu
                 155                 160                 165

 Ser Asn Gly Ala His Phe Ile Cys Asn Tyr Gly Pro Gly Gly Asn
                 170                 175                 180

 Tyr Pro Thr Trp Pro Tyr Lys Arg Gly Ala Thr Cys Ser Ala Cys
                 185                 190                 195

 Pro Asn Asn Asp Lys Cys Leu Asp Asn Leu Cys Val Asn Arg Gln
                 200                 205                 210

 Arg Asp Gln Val Lys Arg Tyr Tyr Ser Val Val Tyr Pro Gly Trp
                 215                 220                 225

 Pro Ile Tyr Pro Arg Asn Arg Tyr Thr Ser Leu Phe Leu Ile Val
                 230                 235                 240

 Asn Ser Val Ile Leu Ile Leu Ser Val Ile Ile Thr Ile Leu Val
                 245                 250                 255

 Gln Leu Lys Tyr Pro Asn Leu Val Leu Leu Asp
                 260                 265

<210> 1099
<211> 4166
<212> DNA
<213> Homo sapien

<400> 1099
 cggcgcgggt gttgagagcg gtgtggtagg tgttgtagcc gctatggtga 50

 agttcgcttt gtagcggccc cggctagaga gttggcctgt tccctgcctt 100

 tgtgacccgg aggagctttt gggggtgcgt caagcccctg gcctgaggca 150

 gcgaactggt ttgtggcctg tttgattcct gtcagaggtt tgctgaccca 200

 agacagtatc gaaaatgcat attaagtcaa ttattctaga gggattcaag 250

 tcctatgctc agaggaccga agtcaatggt tttgaccccc tcttcaatgc 300

 tatcactggc ttaaatggta gtgggaaatc caacatattg gactccatct 350

 gctttttact gggcatctcc aacctgtctc aggttcgggc ttctaattta 400

 caagatttag tttacaaaaa tgggcaggct ggtattacca aagcctctgt 450

 gtcaatcact tttgataatt ctgacaaaaa gcaaagtcct ttaggatttg 500

 aggttcatga tgaaatcaca gtaacaaggc aggtggttat tggtggtaga 550

 aataaatatt taatcaatgg agtcaatgcc aacaacacca gagtacagga 600

 tctcttctgt tctgttggcc ttaatgttaa caaccctcac tttctcatca 650

 tgcagggccg aattacaaaa gtattgaata tgaaaccacc agagatttta 700

 tccatgatag aagaagcagc tggaaccagg atgtatgaat acaaaaaaat 750

 agctgcacag aaaactatag aaaaaaagga ggctaagctg aaagaaatta 800

 agacgatact tgaagaagag attactccaa ccattcaaaa attaaaagag 850

 gaaagatcgt cctacttgga gtaccaaaaa gtaatgagag aaatagaaca 900

 tttgagtcgt ttatatattg cttatcagtt tttgctggct gaagatacca 950

 aagtacgctc agctgaggaa ttaaaagaaa tgcaagataa agttataaag 1000

 cttcaggaag aattgtctga gaatgataaa aaaataaaag cacttaatca 1050

 tgaaatagaa gaattggaaa aaagaaaaga taaggaaact ggagttatac 1100

 ttcgatcttt agaagatgct cttgcagagg ctcagcgagt taatactaaa 1150

 tctcaaagcg catttgatct caagaagaaa aatctggcat gtgaggaaag 1200

 caaacgcaaa gagctggaaa aaaatatggt tgaggactca aaaactttag 1250

 cagcaaagga aaaagaggtt aaaaagataa cagatggact gcatgccctt 1300

 caagaagcaa gtaataaaga tgctgaagct ctggcagctg cacagcagca 1350

 cttcaatgct gtttccgctg gcctgtccag taatgaagat ggagcagaag 1400

 caactcttgc tggtcaaatg atggcctgta aaaatgatat aagtaaagct 1450

 cagacagaag ccaaacaggc tcagatgaag ttgaagcatg ctcaacagga 1500

 attaaagaat aaacaagctg aagttaagaa gatggatagt ggctacagga 1550

 aggatcaaga agctctagaa gctgtaaaaa gacttaaaga aaaacttgaa 1600

 gctgaaatga aaaagctaaa ttatgaagaa aataaagagg aaagcctttt 1650

 ggaaaagcgc aggcagctgt ctcgtgatat tggtagattg aaagaaacat 1700

 atgaagctct attagccaga tttcccaatc ttcgatttgc atacaaggat 1750

 ccagagaaga actggaatag aaattgtgtg aaaggacttg tggcttctct 1800

 gattagtgtg aaagacactt ctgcaaccac agctttagaa ttagtggctg 1850

 gagaacgact ctacaatgtt gtagtagaca cagaagttac tggtaaaaag 1900

 ctactagaaa ggggggaact gaaacgtcga tacactataa ttccactcaa 1950

 taaaatttca gccagatgta ttgcaccaga aactctgaga gttgctcaga 2000

 atcttgttgg ccctgacaac gttcatgtgg ctctttcctt ggttgaatat 2050

 aaaccagaac ttcagaaagc aatggagttt gtctttggaa caacatttgt 2100

 ttgtgacaat atggataatg ccaaaaaagt ggcctttgat aagaggataa 2150

 tgactagaac tgtaactctc ggaggtgatg tgtttgatcc tcatgggaca 2200

 ttgagtggag gtgctcgatc ccaggcagct tccattttaa ccaagtttca 2250

 agaactcaaa gatgttcagg atgaactgag aatcaaagag aatgagctgc 2300

 gggctctaga agaggaatta gcaggtctta aaaacactgc tgaaaagtat 2350

 cgccaactaa aacagcagtg ggagatgaaa actgaagagg cagatttatt 2400

 acaaaccaag ctccagcaaa gctcatatca caagcaacaa gaagaattag 2450

 atgcccttaa aaaaaccatt gaggaaagtg aggagacttt gaaaaacact 2500

 aaagaaatcc aaagaaaagc agaagaaaaa tatgaagtat tggaaaataa 2550

 aatgaaaaat gcagaagctg aaagagagcg agaactgaaa gatgctcaga 2600

 aaaaactgga ttgtgccaaa acaaaggcag atgcatctag caagaagatg 2650

 aaagaaaaac aacaggaagt tgaagctatc actctggaac tggaagagct 2700

 caagagagag catacatctt acaaacaaca gcttgaagct gtaaatgaag 2750

 ctatcaaatc ctatgaaagt cagattgaag taatggcagc tgaggtggct 2800

 aaaaataagg agtcagtaaa taaagctcaa gaagaggtga ccaagcaaaa 2850

 agaggtgata acagcccaag acactgtaat taagctaaat atgcagaagt 2900

 ggcaaaacac aaggagcaaa acaatgattc tcagccttaa aattaaggaa 2950

 ttagaccacc acatcagcaa acataaacgg gaggctgaag atggtgctgc 3000

 aaaggtatcc aaaatgttga aagattatga ctggattaat gcagagagac 3050

 acctctttgg ccaacccaat agtgcctatg atttcaaaac taacaaccct 3100

 aaagaagctg gtcagagact tcagaagttg caagaaatga aggagaaact 3150

 aggaagaaat gtcaatatga gagctatgaa tgtattgaca gaagctgaag 3200

 agcgatgcaa tgacttgatg aagaagaaga gaattgtaga aaatgacaaa 3250

 tccaaaattc ttacaactat agaagacctt gaccagaaga aaaaccaagc 3300

 cctaaatatt gcatggcaaa aggtgaacaa ggactttggg tctatttttt 3350

 ctactctttt gcctggtgct aatgctatgc ttgcaccacc agagggtcaa 3400

 actgttttgg atggtctgga gttcaaggtt gccttaggaa atacctggaa 3450

 agaaaaccta actgaactta gtggtggtca gaggtcttta gtggccttgt 3500

 cattaatact gtccatgctt ctcttcaaac ctgctccaat ttatatcctt 3550

 gatgaggtag atgcagcctt ggatctttct catacccaaa acattggaca 3600

 gatgctgcgt actcatttca cacattctca gttcattgtg gtgtcactaa 3650

 aagaaggtat gttcaacaat gcaaacgttc ttttcaaaac caagtttgtg 3700

 gatggtgttt ctacagtagc cagatttact caatgtcaaa atggaaagat 3750

 ttcaaaggaa gcaaaatcca aggcaaaacc acccaaagga gcacatgtgg 3800

 aagtttaaac tacaaagtta tttcttcatc ttgacctgtt tttttaaatg 3850

 taaactttta aggacttgag ataactaatt tgtttatata caaaaattaa 3900

 tgttactgtg ttacttaacc catgttttct ctttatataa tcacttatcg 3950

 cttacaaatg agcatatatt cctcatctct taactagtct aattatggtc 4000

 caattattgt ggttgtgatt ttatgcatat ccatcaaaat gttttttttc 4050

 ttatgcgggt cttttatata ttagggatcc tgagataccc gattctatat 4100

 gtaaaagcta atatacaaaa aagcagatta aattacatga taaatgtagc 4150

 tgaaaaaaaa aaaaaa 4166

<210> 1100
<211> 1197
<212> PRT
<213> Homo sapien

<400> 1100
 Met His Ile Lys Ser Ile Ile Leu Glu Gly Phe Lys Ser Tyr Ala
   1               5                  10                  15

 Gln Arg Thr Glu Val Asn Gly Phe Asp Pro Leu Phe Asn Ala Ile
                  20                  25                  30

 Thr Gly Leu Asn Gly Ser Gly Lys Ser Asn Ile Leu Asp Ser Ile
                  35                  40                  45

 Cys Phe Leu Leu Gly Ile Ser Asn Leu Ser Gln Val Arg Ala Ser
                  50                  55                  60

 Asn Leu Gln Asp Leu Val Tyr Lys Asn Gly Gln Ala Gly Ile Thr
                  65                  70                  75

 Lys Ala Ser Val Ser Ile Thr Phe Asp Asn Ser Asp Lys Lys Gln
                  80                  85                  90

 Ser Pro Leu Gly Phe Glu Val His Asp Glu Ile Thr Val Thr Arg
                  95                 100                 105

 Gln Val Val Ile Gly Gly Arg Asn Lys Tyr Leu Ile Asn Gly Val
                 110                 115                 120

 Asn Ala Asn Asn Thr Arg Val Gln Asp Leu Phe Cys Ser Val Gly
                 125                 130                 135

 Leu Asn Val Asn Asn Pro His Phe Leu Ile Met Gln Gly Arg Ile
                 140                 145                 150

 Thr Lys Val Leu Asn Met Lys Pro Pro Glu Ile Leu Ser Met Ile
                 155                 160                 165

 Glu Glu Ala Ala Gly Thr Arg Met Tyr Glu Tyr Lys Lys Ile Ala
                 170                 175                 180

 Ala Gln Lys Thr Ile Glu Lys Lys Glu Ala Lys Leu Lys Glu Ile
                 185                 190                 195

 Lys Thr Ile Leu Glu Glu Glu Ile Thr Pro Thr Ile Gln Lys Leu
                 200                 205                 210

 Lys Glu Glu Arg Ser Ser Tyr Leu Glu Tyr Gln Lys Val Met Arg
                 215                 220                 225

 Glu Ile Glu His Leu Ser Arg Leu Tyr Ile Ala Tyr Gln Phe Leu
                 230                 235                 240

 Leu Ala Glu Asp Thr Lys Val Arg Ser Ala Glu Glu Leu Lys Glu
                 245                 250                 255

 Met Gln Asp Lys Val Ile Lys Leu Gln Glu Glu Leu Ser Glu Asn
                 260                 265                 270

 Asp Lys Lys Ile Lys Ala Leu Asn His Glu Ile Glu Glu Leu Glu
                 275                 280                 285

 Lys Arg Lys Asp Lys Glu Thr Gly Val Ile Leu Arg Ser Leu Glu
                 290                 295                 300

 Asp Ala Leu Ala Glu Ala Gln Arg Val Asn Thr Lys Ser Gln Ser
                 305                 310                 315

 Ala Phe Asp Leu Lys Lys Lys Asn Leu Ala Cys Glu Glu Ser Lys
                 320                 325                 330

 Arg Lys Glu Leu Glu Lys Asn Met Val Glu Asp Ser Lys Thr Leu
                 335                 340                 345

 Ala Ala Lys Glu Lys Glu Val Lys Lys Ile Thr Asp Gly Leu His
                 350                 355                 360

 Ala Leu Gln Glu Ala Ser Asn Lys Asp Ala Glu Ala Leu Ala Ala
                 365                 370                 375

 Ala Gln Gln His Phe Asn Ala Val Ser Ala Gly Leu Ser Ser Asn
                 380                 385                 390

 Glu Asp Gly Ala Glu Ala Thr Leu Ala Gly Gln Met Met Ala Cys
                 395                 400                 405

 Lys Asn Asp Ile Ser Lys Ala Gln Thr Glu Ala Lys Gln Ala Gln
                 410                 415                 420

 Met Lys Leu Lys His Ala Gln Gln Glu Leu Lys Asn Lys Gln Ala
                 425                 430                 435

 Glu Val Lys Lys Met Asp Ser Gly Tyr Arg Lys Asp Gln Glu Ala
                 440                 445                 450

 Leu Glu Ala Val Lys Arg Leu Lys Glu Lys Leu Glu Ala Glu Met
                 455                 460                 465

 Lys Lys Leu Asn Tyr Glu Glu Asn Lys Glu Glu Ser Leu Leu Glu
                 470                 475                 480

 Lys Arg Arg Gln Leu Ser Arg Asp Ile Gly Arg Leu Lys Glu Thr
                 485                 490                 495

 Tyr Glu Ala Leu Leu Ala Arg Phe Pro Asn Leu Arg Phe Ala Tyr
                 500                 505                 510

 Lys Asp Pro Glu Lys Asn Trp Asn Arg Asn Cys Val Lys Gly Leu
                 515                 520                 525

 Val Ala Ser Leu Ile Ser Val Lys Asp Thr Ser Ala Thr Thr Ala
                 530                 535                 540

 Leu Glu Leu Val Ala Gly Glu Arg Leu Tyr Asn Val Val Val Asp
                 545                 550                 555

 Thr Glu Val Thr Gly Lys Lys Leu Leu Glu Arg Gly Glu Leu Lys
                 560                 565                 570

 Arg Arg Tyr Thr Ile Ile Pro Leu Asn Lys Ile Ser Ala Arg Cys
                 575                 580                 585

 Ile Ala Pro Glu Thr Leu Arg Val Ala Gln Asn Leu Val Gly Pro
                 590                 595                 600

 Asp Asn Val His Val Ala Leu Ser Leu Val Glu Tyr Lys Pro Glu
                 605                 610                 615

 Leu Gln Lys Ala Met Glu Phe Val Phe Gly Thr Thr Phe Val Cys
                 620                 625                 630

 Asp Asn Met Asp Asn Ala Lys Lys Val Ala Phe Asp Lys Arg Ile
                 635                 640                 645

 Met Thr Arg Thr Val Thr Leu Gly Gly Asp Val Phe Asp Pro His
                 650                 655                 660

 Gly Thr Leu Ser Gly Gly Ala Arg Ser Gln Ala Ala Ser Ile Leu
                 665                 670                 675

 Thr Lys Phe Gln Glu Leu Lys Asp Val Gln Asp Glu Leu Arg Ile
                 680                 685                 690

 Lys Glu Asn Glu Leu Arg Ala Leu Glu Glu Glu Leu Ala Gly Leu
                 695                 700                 705

 Lys Asn Thr Ala Glu Lys Tyr Arg Gln Leu Lys Gln Gln Trp Glu
                 710                 715                 720

 Met Lys Thr Glu Glu Ala Asp Leu Leu Gln Thr Lys Leu Gln Gln
                 725                 730                 735

 Ser Ser Tyr His Lys Gln Gln Glu Glu Leu Asp Ala Leu Lys Lys
                 740                 745                 750

 Thr Ile Glu Glu Ser Glu Glu Thr Leu Lys Asn Thr Lys Glu Ile
                 755                 760                 765

 Gln Arg Lys Ala Glu Glu Lys Tyr Glu Val Leu Glu Asn Lys Met
                 770                 775                 780

 Lys Asn Ala Glu Ala Glu Arg Glu Arg Glu Leu Lys Asp Ala Gln
                 785                 790                 795

 Lys Lys Leu Asp Cys Ala Lys Thr Lys Ala Asp Ala Ser Ser Lys
                 800                 805                 810

 Lys Met Lys Glu Lys Gln Gln Glu Val Glu Ala Ile Thr Leu Glu
                 815                 820                 825

 Leu Glu Glu Leu Lys Arg Glu His Thr Ser Tyr Lys Gln Gln Leu
                 830                 835                 840

 Glu Ala Val Asn Glu Ala Ile Lys Ser Tyr Glu Ser Gln Ile Glu
                 845                 850                 855

 Val Met Ala Ala Glu Val Ala Lys Asn Lys Glu Ser Val Asn Lys
                 860                 865                 870

 Ala Gln Glu Glu Val Thr Lys Gln Lys Glu Val Ile Thr Ala Gln
                 875                 880                 885

 Asp Thr Val Ile Lys Leu Asn Met Gln Lys Trp Gln Asn Thr Arg
                 890                 895                 900

 Ser Lys Thr Met Ile Leu Ser Leu Lys Ile Lys Glu Leu Asp His
                 905                 910                 915

 His Ile Ser Lys His Lys Arg Glu Ala Glu Asp Gly Ala Ala Lys
                 920                 925                 930

 Val Ser Lys Met Leu Lys Asp Tyr Asp Trp Ile Asn Ala Glu Arg
                 935                 940                 945

 His Leu Phe Gly Gln Pro Asn Ser Ala Tyr Asp Phe Lys Thr Asn
                 950                 955                 960

 Asn Pro Lys Glu Ala Gly Gln Arg Leu Gln Lys Leu Gln Glu Met
                 965                 970                 975

 Lys Glu Lys Leu Gly Arg Asn Val Asn Met Arg Ala Met Asn Val
                 980                 985                 990

 Leu Thr Glu Ala Glu Glu Arg Cys Asn Asp Leu Met Lys Lys Lys
                 995                1000                1005

 Arg Ile Val Glu Asn Asp Lys Ser Lys Ile Leu Thr Thr Ile Glu
                1010                1015                1020

 Asp Leu Asp Gln Lys Lys Asn Gln Ala Leu Asn Ile Ala Trp Gln
                1025                1030                1035

 Lys Val Asn Lys Asp Phe Gly Ser Ile Phe Ser Thr Leu Leu Pro
                1040                1045                1050

 Gly Ala Asn Ala Met Leu Ala Pro Pro Glu Gly Gln Thr Val Leu
                1055                1060                1065

 Asp Gly Leu Glu Phe Lys Val Ala Leu Gly Asn Thr Trp Lys Glu
                1070                1075                1080

 Asn Leu Thr Glu Leu Ser Gly Gly Gln Arg Ser Leu Val Ala Leu
                1085                1090                1095

 Ser Leu Ile Leu Ser Met Leu Leu Phe Lys Pro Ala Pro Ile Tyr
                1100                1105                1110

 Ile Leu Asp Glu Val Asp Ala Ala Leu Asp Leu Ser His Thr Gln
                1115                1120                1125

 Asn Ile Gly Gln Met Leu Arg Thr His Phe Thr His Ser Gln Phe
                1130                1135                1140

 Ile Val Val Ser Leu Lys Glu Gly Met Phe Asn Asn Ala Asn Val
                1145                1150                1155

 Leu Phe Lys Thr Lys Phe Val Asp Gly Val Ser Thr Val Ala Arg
                1160                1165                1170

 Phe Thr Gln Cys Gln Asn Gly Lys Ile Ser Lys Glu Ala Lys Ser
                1175                1180                1185

 Lys Ala Lys Pro Pro Lys Gly Ala His Val Glu Val
                1190                1195

<210> 1101
<211> 2328
<212> DNA
<213> Homo sapien

<400> 1101
 ggaagcaggg cggggcctct ggtggcggtc gggaactcgg tgggaggcgg 50

 caacattgtt tcaagttggc caaattgaca agagcgagag gtatactgcg 100

 ttccatcccg acccggggcc acggtactgg gccctgtttc cccctcctcg 150

 gcccccgaga gccagggtcc gccttctgca gggttcccag gcccccgctc 200

 cagggccggg ctgacccgac tcgctggcgc ttcatggaga acttccaaaa 250

 ggtggaaaag atcggagagg gcacgtacgg agttgtgtac aaagccagaa 300

 acaagttgac gggagaggtg gtggcgctta agaaaatccg cctggacact 350

 gagactgagg gtgtgcccag tactgccatc cgagagatct ctctgcttaa 400

 ggagcttaac catcctaata ttgtcaagct gctggatgtc attcacacag 450

 aaaataaact ctacctggtt tttgaatttc tgcaccaaga tctcaagaaa 500

 ttcatggatg cctctgctct cactggcatt cctcttcccc tcatcaagag 550

 ctatctgttc cagctgctcc agggcctagc tttctgccat tctcatcggg 600

 tcctccaccg agaccttaaa cctcagaatc tgcttattaa cacagagggg 650

 gccatcaagc tagcagactt tggactagcc agagcttttg gagtccctgt 700

 tcgtacttac acccatgagg tggtgaccct gtggtaccga gctcctgaaa 750

 tcctcctggg ctgcaaatat tattccacag ctgtggacat ctggagcctg 800

 ggctgcatct ttgctgagat ggtgactcgc cgggccctat tccctggaga 850

 ttctgagatt gaccagctct tccggatctt tcggactctg gggaccccag 900

 atgaggtggt gtggccagga gttacttcta tgcctgatta caagccaagt 950

 ttccccaagt gggcccggca agattttagt aaagttgtac ctcccctgga 1000

 tgaagatgga cggagcttgt tatcgcaaat gctgcactac gaccctaaca 1050

 agcggatttc ggccaaggca gccctggctc accctttctt ccaggatgtg 1100

 accaagccag taccccatct tcgactctga tagccttctt gaagccccca 1150

 gccctaatct caccctctcc tccagtgtgg gcttgaccag gcttggcctt 1200

 gggctatttg gactcaggtg ggccctctga acttgcctta aacactcacc 1250

 ttctagtctt ggccagccaa ctctgggaat acaggggtga aaggggggaa 1300

 ccagtgaaaa tgaaaggaag tttcagtatt agatgcactt aagttagcct 1350

 ccaccaccct ttcccccttc tcttagttat tgctgaagag ggttggtata 1400

 aaaataattt taaaaaagcc ttcctacacg ttagatttgc cgtaccaatc 1450

 tctgaatgcc ccataattat tatttccagt gtttgggatg accaggatcc 1500

 caagcctcct gctgccacaa tgtttataaa ggccaaatga tagcgggggc 1550

 taagttggtg cttttgagaa ccaagtaaaa caaaaccact gggaggagtc 1600

 tattttaaag aattcggttg aaaaaataga tccaatcagt ttatacccta 1650

 gttagtgttt tgcctcacct aataggctgg gagactgaag actcagcccg 1700

 ggtggggctg cagaaaaatg attggcccca gtccccttgt ttgtcccttc 1750

 tacaggcatg aggaatctgg gaggccctga gacagggatt gtgcttcatt 1800

 ccaatctatt gcttcaccat ggccttatga ggcaggtgag agatgtttga 1850

 atttttctct tccttttagt attcttagtt gttcagttgc caaggatccc 1900

 tgatcccatt ttcctctgac gtccacctcc taccccatag gagttagaag 1950

 ttagggttta ggcatcattt tgagaatgct gacacttttt cagggctgtg 2000

 attgagtgag ggcatgggta aaaatatttc tttaaaagaa ggatgaacaa 2050

 ttatatttat atttcaggtt atatccaata gtagagttgg cttttttttt 2100

 tttttttttg gtcatagtgg gtggatttgt tgccatgtgc accttggggt 2150

 tttgtaatga cagtgctaaa aaaaaaaaag catttttttt tatgatttgt 2200

 ctctgtcacc cttgtccttg agtgctcttg ctattaacgt tatttgtaat 2250

 ttagtttgta gctcattaaa aaaatgtgcc tagttttata aaaaaaaaaa 2300

 aaaaaaaaaa aaaaaaaaaa aaaaaaaa 2328

<210> 1102
<211> 298
<212> PRT
<213> Homo sapien

<400> 1102
 Met Glu Asn Phe Gln Lys Val Glu Lys Ile Gly Glu Gly Thr Tyr
   1               5                  10                  15

 Gly Val Val Tyr Lys Ala Arg Asn Lys Leu Thr Gly Glu Val Val
                  20                  25                  30

 Ala Leu Lys Lys Ile Arg Leu Asp Thr Glu Thr Glu Gly Val Pro
                  35                  40                  45

 Ser Thr Ala Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Asn His
                  50                  55                  60

 Pro Asn Ile Val Lys Leu Leu Asp Val Ile His Thr Glu Asn Lys
                  65                  70                  75

 Leu Tyr Leu Val Phe Glu Phe Leu His Gln Asp Leu Lys Lys Phe
                  80                  85                  90

 Met Asp Ala Ser Ala Leu Thr Gly Ile Pro Leu Pro Leu Ile Lys
                  95                 100                 105

 Ser Tyr Leu Phe Gln Leu Leu Gln Gly Leu Ala Phe Cys His Ser
                 110                 115                 120

 His Arg Val Leu His Arg Asp Leu Lys Pro Gln Asn Leu Leu Ile
                 125                 130                 135

 Asn Thr Glu Gly Ala Ile Lys Leu Ala Asp Phe Gly Leu Ala Arg
                 140                 145                 150

 Ala Phe Gly Val Pro Val Arg Thr Tyr Thr His Glu Val Val Thr
                 155                 160                 165

 Leu Trp Tyr Arg Ala Pro Glu Ile Leu Leu Gly Cys Lys Tyr Tyr
                 170                 175                 180

 Ser Thr Ala Val Asp Ile Trp Ser Leu Gly Cys Ile Phe Ala Glu
                 185                 190                 195

 Met Val Thr Arg Arg Ala Leu Phe Pro Gly Asp Ser Glu Ile Asp
                 200                 205                 210

 Gln Leu Phe Arg Ile Phe Arg Thr Leu Gly Thr Pro Asp Glu Val
                 215                 220                 225

 Val Trp Pro Gly Val Thr Ser Met Pro Asp Tyr Lys Pro Ser Phe
                 230                 235                 240

 Pro Lys Trp Ala Arg Gln Asp Phe Ser Lys Val Val Pro Pro Leu
                 245                 250                 255

 Asp Glu Asp Gly Arg Ser Leu Leu Ser Gln Met Leu His Tyr Asp
                 260                 265                 270

 Pro Asn Lys Arg Ile Ser Ala Lys Ala Ala Leu Ala His Pro Phe
                 275                 280                 285

 Phe Gln Asp Val Thr Lys Pro Val Pro His Leu Arg Leu
                 290                 295

<210> 1103
<211> 4604
<212> DNA
<213> Homo sapien

<400> 1103
 ggaacagctt gtccacccgc cggccggacc agaagccttt gggtctgaag 50

 tgtctgtgag acctcacaga agagcacccc tgggctccac ttacctgccc 100

 cctgctcctt cagggatgga ggcaatggcg gccagcactt ccctgcctga 150

 ccctggagac tttgaccgga acgtgccccg gatctgtggg gtgtgtggag 200

 accgagccac tggctttcac ttcaatgcta tgacctgtga aggctgcaaa 250

 ggcttcttca ggcgaagcat gaagcggaag gcactattca cctgcccctt 300

 caacggggac tgccgcatca ccaaggacaa ccgacgccac tgccaggcct 350

 gccggctcaa acgctgtgtg gacatcggca tgatgaagga gttcattctg 400

 acagatgagg aagtgcagag gaagcgggag atgatcctga agcggaagga 450

 ggaggaggcc ttgaaggaca gtctgcggcc caagctgtct gaggagcagc 500

 agcgcatcat tgccatactg ctggacgccc accataagac ctacgacccc 550

 acctactccg acttctgcca gttccggcct ccagttcgtg tgaatgatgg 600

 tggagggagc catccttcca ggcccaactc cagacacact cccagcttct 650

 ctggggactc ctcctcctcc tgctcagatc actgtatcac ctcttcagac 700

 atgatggact cgtccagctt ctccaatctg gatctgagtg aagaagattc 750

 agatgaccct tctgtgaccc tagagctgtc ccagctctcc atgctgcccc 800

 acctggctga cctggtcagt tacagcatcc aaaaggtcat tggctttgct 850

 aagatgatac caggattcag agacctcacc tctgaggacc agatcgtact 900

 gctgaagtca agtgccattg aggtcatcat gttgcgctcc aatgagtcct 950

 tcaccatgga cgacatgtcc tggacctgtg gcaaccaaga ctacaagtac 1000

 cgcgtcagtg acgtgaccaa agccggacac agcctggagc tgattgagcc 1050

 cctcatcaag ttccaggtgg gactgaagaa gctgaacttg catgaggagg 1100

 agcatgtcct gctcatggcc atctgcatcg tctccccaga tcgtcctggg 1150

 gtgcaggacg ccgcgctgat tgaggccatc caggaccgcc tgtccaacac 1200

 actgcagacg tacatccgct gccgccaccc gcccccgggc agccacctgc 1250

 tctatgccaa gatgatccag aagctagccg acctgcgcag cctcaatgag 1300

 gagcactcca agcagtaccg ctgcctctcc ttccagcctg agtgcagcat 1350

 gaagctaacg ccccttgtgc tcgaagtgtt tggcaatgag atctcctgac 1400

 taggacagcc tgtgcggtgc ctgggtgggg ctgctcctcc agggccacgt 1450

 gccaggcccg gggctggcgg ctactcagca gccctcctca cccgtctggg 1500

 gttcagcccc tcctctgcca cctcccctat ccacccagcc cattctctct 1550

 cctgtccaac ctaacccctt tcctgcgggc ttttccccgg tcccttgaga 1600

 cctcagccat gaggagttgc tgtttgtttg acaaagaaac ccaagtgggg 1650

 gcagagggca gaggctggag gcaggccttg cccagagatg cctccaccgc 1700

 tgcctaagtg gctgctgact gatgttgagg gaacagacag gagaaatgca 1750

 tccattcctc agggacagag acacctgcac ctccccccac tgcaggcccc 1800

 gcttgtccag cgcctagtgg ggtctccctc tcctgcctta ctcacgataa 1850

 ataatcggcc cacagctccc accccacccc cttcagtgcc caccaacatc 1900

 ccattgccct ggttatattc tcacgggcag tagctgtggt gaggtgggtt 1950

 ttcttcccat cactggagca ccaggcacga acccacctgc tgagagaccc 2000

 aaggaggaaa aacagacaaa aacagcctca cagaagaata tgacagctgt 2050

 ccctgtcacc aagctcacag ttcctcgccc tgggtctaag gggttggttg 2100

 aggtggaagc cctccttcca cggatccatg tagcaggact gaattgtccc 2150

 cagtttgcag aaaagcacct gccgacctcg tcctccccct gccagtgcct 2200

 tacctcctgc ccaggagagc cagccctccc tgtcctcctc ggatcaccga 2250

 gagtagccga gagcctgctc ccccaccccc tccccagggg agagggtctg 2300

 gagaagcagt gagccgcatc ttctccatct ggcagggtgg gatggaggag 2350

 aagaattttc agaccccagc ggctgagtca tgatctccct gccgcctcaa 2400

 tgtggttgca aggccgctgt tcaccacagg gctaagagct aggctgccgc 2450

 accccagagt gtgggaaggg agagcggggc agtctcgggt ggctagtcag 2500

 agagagtgtt tgggggttcc gtgatgtagg gtaaggtgcc ttcttattct 2550

 cactccacca cccaaaagtc aaaaggtgcc tgtgaggcag gggcggagtg 2600

 atacaacttc aagtgcatgc tctctgcagg tcgagcccag cccagctggt 2650

 gggaagcgtc tgtccgttta ctccaaggtg ggtctttgtg agagtgagct 2700

 gtaggtgtgc gggaccggta cagaaaggcg ttcttcgagg tggatcacag 2750

 aggcttcttc agatcaatgc ttgagtttgg aatcggccgc attccctgag 2800

 tcaccaggaa tgttaaagtc agtgggaacg tgactgcccc aactcctgga 2850

 agctgtgtcc ttgcacctgc atccgtagtt ccctgaaaac ccagagagga 2900

 atcagacttc acactgcaag agccttggtg tccacctggc cccatgtctc 2950

 tcagaattct tcaggtggaa aaacatctga aagccacgtt ccttactgca 3000

 gaatagcata tatatcgctt aatcttaaat ttattagata tgagttgttt 3050

 tcagactcag actccatttg tattatagtc taatatacag ggtagcaggt 3100

 accactgatt tggagatatt tatgggggga gaacttacat tgtgaaactt 3150

 ctgtacatta attattattg ctgttgttat tttacaaggg tctagggaga 3200

 gacccttgtt tgattttagc tgcagaactg tattggtcca gcttgctctt 3250

 cagtgggaga aaaacacttg taagttgcta aacgagtcaa tcccctcatt 3300

 caggaaaact gacagaggag ggcgtgactc acccaagcca tatataacta 3350

 gctagaagtg ggccaggaca ggccgggcgc ggtggctcac gcctgtaatc 3400

 ccagcagttt gggaggtcga ggtaggtgga tcacctgagg tcgggagttc 3450

 gagaccaacc tgaccaacat ggagaaaccc tgtctctatt aaaaatacaa 3500

 aaaaaaaaaa aaaaaaaaat agccgggcat ggtggcgcaa gcctgtaatc 3550

 ccagctactc aggaggctga ggcagaagaa ttgaacccag gaggtggagg 3600

 ttgcagtgag ctgagatcgt gccgttactc tccaacctgg acaacaagag 3650

 cgaaactccg tcttagaagt ggaccaggac aggaccagat tttggagtca 3700

 tggtccggtg tccttttcac tacaccatgt ttgagctcag acccccactc 3750

 tcattcccca ggtggctgac ccagtccctg ggggaagccc tggatttcag 3800

 aaagagccaa gtctggatct gggacccttt ccttccttcc ctggcttgta 3850

 actccaccaa gcccatcaga aggagaagga aggagactca cctctgcctc 3900

 aatgtgaatc agaccctacc ccaccacgat gtgccctggc tgctgggctc 3950

 tccacctcag gccttggata atgctgttgc ctcatctata acatgcattt 4000

 gtctttgtaa tgtcaccacc ttcccagctc tccctctggc cctgcttctt 4050

 cggggaactc ctgaaatatc agttactcag ccctgggccc caccacctag 4100

 gccactcctc caaaggaagt ctaggagctg ggaggaaaag aaaagagggg 4150

 aaaatgagtt tttatggggc tgaacgggga gaaaaggtca tcatcgattc 4200

 tactttagaa tgagagtgtg aaatagacat ttgtaaatgt aaaactttta 4250

 aggtatatca ttataactga aggagaaggt gccccaaaat gcaagatttt 4300

 ccacaagatt cccagagaca ggaaaatcct ctggctggct aactggaagc 4350

 atgtaggaga atccaagcga ggtcaacaga gaaggcagga atgtgtggca 4400

 gatttagtga aagctagaga tatggcagcg aaaggatgta aacagtgcct 4450

 gctgaatgat ttccaaagag aaaaaaagtt tgccagaagt ttgtcaagtc 4500

 aaccaatgta gaaagctttg cttatggtaa taaaaatggc tcatacttat 4550

 atagcactta ctttgtttgc aagtactgct gtaaataaat gctttatgca 4600

 aacc 4604

<210> 1104
<211> 427
<212> PRT
<213> Homo sapien

<400> 1104
 Met Glu Ala Met Ala Ala Ser Thr Ser Leu Pro Asp Pro Gly Asp
   1               5                  10                  15

 Phe Asp Arg Asn Val Pro Arg Ile Cys Gly Val Cys Gly Asp Arg
                  20                  25                  30

 Ala Thr Gly Phe His Phe Asn Ala Met Thr Cys Glu Gly Cys Lys
                  35                  40                  45

 Gly Phe Phe Arg Arg Ser Met Lys Arg Lys Ala Leu Phe Thr Cys
                  50                  55                  60

 Pro Phe Asn Gly Asp Cys Arg Ile Thr Lys Asp Asn Arg Arg His
                  65                  70                  75

 Cys Gln Ala Cys Arg Leu Lys Arg Cys Val Asp Ile Gly Met Met
                  80                  85                  90

 Lys Glu Phe Ile Leu Thr Asp Glu Glu Val Gln Arg Lys Arg Glu
                  95                 100                 105

 Met Ile Leu Lys Arg Lys Glu Glu Glu Ala Leu Lys Asp Ser Leu
                 110                 115                 120

 Arg Pro Lys Leu Ser Glu Glu Gln Gln Arg Ile Ile Ala Ile Leu
                 125                 130                 135

 Leu Asp Ala His His Lys Thr Tyr Asp Pro Thr Tyr Ser Asp Phe
                 140                 145                 150

 Cys Gln Phe Arg Pro Pro Val Arg Val Asn Asp Gly Gly Gly Ser
                 155                 160                 165

 His Pro Ser Arg Pro Asn Ser Arg His Thr Pro Ser Phe Ser Gly
                 170                 175                 180

 Asp Ser Ser Ser Ser Cys Ser Asp His Cys Ile Thr Ser Ser Asp
                 185                 190                 195

 Met Met Asp Ser Ser Ser Phe Ser Asn Leu Asp Leu Ser Glu Glu
                 200                 205                 210

 Asp Ser Asp Asp Pro Ser Val Thr Leu Glu Leu Ser Gln Leu Ser
                 215                 220                 225

 Met Leu Pro His Leu Ala Asp Leu Val Ser Tyr Ser Ile Gln Lys
                 230                 235                 240

 Val Ile Gly Phe Ala Lys Met Ile Pro Gly Phe Arg Asp Leu Thr
                 245                 250                 255

 Ser Glu Asp Gln Ile Val Leu Leu Lys Ser Ser Ala Ile Glu Val
                 260                 265                 270

 Ile Met Leu Arg Ser Asn Glu Ser Phe Thr Met Asp Asp Met Ser
                 275                 280                 285

 Trp Thr Cys Gly Asn Gln Asp Tyr Lys Tyr Arg Val Ser Asp Val
                 290                 295                 300

 Thr Lys Ala Gly His Ser Leu Glu Leu Ile Glu Pro Leu Ile Lys
                 305                 310                 315

 Phe Gln Val Gly Leu Lys Lys Leu Asn Leu His Glu Glu Glu His
                 320                 325                 330

 Val Leu Leu Met Ala Ile Cys Ile Val Ser Pro Asp Arg Pro Gly
                 335                 340                 345

 Val Gln Asp Ala Ala Leu Ile Glu Ala Ile Gln Asp Arg Leu Ser
                 350                 355                 360

 Asn Thr Leu Gln Thr Tyr Ile Arg Cys Arg His Pro Pro Pro Gly
                 365                 370                 375

 Ser His Leu Leu Tyr Ala Lys Met Ile Gln Lys Leu Ala Asp Leu
                 380                 385                 390

 Arg Ser Leu Asn Glu Glu His Ser Lys Gln Tyr Arg Cys Leu Ser
                 395                 400                 405

 Phe Gln Pro Glu Cys Ser Met Lys Leu Thr Pro Leu Val Leu Glu
                 410                 415                 420

 Val Phe Gly Asn Glu Ile Ser
                 425

<210> 1105
<211> 4604
<212> DNA
<213> Homo sapien

<400> 1105
 ggaacagctt gtccacccgc cggccggacc agaagccttt gggtctgaag 50

 tgtctgtgag acctcacaga agagcacccc tgggctccac ttacctgccc 100

 cctgctcctt cagggatgga ggcaatggcg gccagcactt ccctgcctga 150

 ccctggagac tttgaccgga acgtgccccg gatctgtggg gtgtgtggag 200

 accgagccac tggctttcac ttcaatgcta tgacctgtga aggctgcaaa 250

 ggcttcttca ggcgaagcat gaagcggaag gcactattca cctgcccctt 300

 caacggggac tgccgcatca ccaaggacaa ccgacgccac tgccaggcct 350

 gccggctcaa acgctgtgtg gacatcggca tgatgaagga gttcattctg 400

 acagatgagg aagtgcagag gaagcgggag atgatcctga agcggaagga 450

 ggaggaggcc ttgaaggaca gtctgcggcc caagctgtct gaggagcagc 500

 agcgcatcat tgccatactg ctggacgccc accataagac ctacgacccc 550

 acctactccg acttctgcca gttccggcct ccagttcgtg tgaatgatgg 600

 tggagggagc catccttcca ggcccaactc cagacacact cccagcttct 650

 ctggggactc ctcctcctcc tgctcagatc actgtatcac ctcttcagac 700

 atgatggact cgtccagctt ctccaatctg gatctgagtg aagaagattc 750

 agatgaccct tctgtgaccc tagagctgtc ccagctctcc atgctgcccc 800

 acctggctga cctggtcagt tacagcatcc aaaaggtcat tggctttgct 850

 aagatgatac caggattcag agacctcacc tctgaggacc agatcgtact 900

 gctgaagtca agtgccattg aggtcatcat gttgcgctcc aatgagtcct 950

 tcaccatgga cgacatgtcc tggacctgtg gcaaccaaga ctacaagtac 1000

 cgcgtcagtg acgtgaccaa agccggacac agcctggagc tgattgagcc 1050

 cctcatcaag ttccaggtgg gactgaagaa gctgaacttg catgaggagg 1100

 agcatgtcct gctcatggcc atctgcatcg tctccccaga tcgtcctggg 1150

 gtgcaggacg ccgcgctgat tgaggccatc caggaccgcc tgtccaacac 1200

 actgcagacg tacatccgct gccgccaccc gcccccgggc agccacctgc 1250

 tctatgccaa gatgatccag aagctagccg acctgcgcag cctcaatgag 1300

 gagcactcca agcagtaccg ctgcctctcc ttccagcctg agtgcagcat 1350

 gaagctaacg ccccttgtgc tcgaagtgtt tggcaatgag atctcctgac 1400

 taggacagcc tgtgcggtgc ctgggtgggg ctgctcctcc agggccacgt 1450

 gccaggcccg gggctggcgg ctactcagca gccctcctca cccgtctggg 1500

 gttcagcccc tcctctgcca cctcccctat ccacccagcc cattctctct 1550

 cctgtccaac ctaacccctt tcctgcgggc ttttccccgg tcccttgaga 1600

 cctcagccat gaggagttgc tgtttgtttg acaaagaaac ccaagtgggg 1650

 gcagagggca gaggctggag gcaggccttg cccagagatg cctccaccgc 1700

 tgcctaagtg gctgctgact gatgttgagg gaacagacag gagaaatgca 1750

 tccattcctc agggacagag acacctgcac ctccccccac tgcaggcccc 1800

 gcttgtccag cgcctagtgg ggtctccctc tcctgcctta ctcacgataa 1850

 ataatcggcc cacagctccc accccacccc cttcagtgcc caccaacatc 1900

 ccattgccct ggttatattc tcacgggcag tagctgtggt gaggtgggtt 1950

 ttcttcccat cactggagca ccaggcacga acccacctgc tgagagaccc 2000

 aaggaggaaa aacagacaaa aacagcctca cagaagaata tgacagctgt 2050

 ccctgtcacc aagctcacag ttcctcgccc tgggtctaag gggttggttg 2100

 aggtggaagc cctccttcca cggatccatg tagcaggact gaattgtccc 2150

 cagtttgcag aaaagcacct gccgacctcg tcctccccct gccagtgcct 2200

 tacctcctgc ccaggagagc cagccctccc tgtcctcctc ggatcaccga 2250

 gagtagccga gagcctgctc ccccaccccc tccccagggg agagggtctg 2300

 gagaagcagt gagccgcatc ttctccatct ggcagggtgg gatggaggag 2350

 aagaattttc agaccccagc ggctgagtca tgatctccct gccgcctcaa 2400

 tgtggttgca aggccgctgt tcaccacagg gctaagagct aggctgccgc 2450

 accccagagt gtgggaaggg agagcggggc agtctcgggt ggctagtcag 2500

 agagagtgtt tgggggttcc gtgatgtagg gtaaggtgcc ttcttattct 2550

 cactccacca cccaaaagtc aaaaggtgcc tgtgaggcag gggcggagtg 2600

 atacaacttc aagtgcatgc tctctgcagg tcgagcccag cccagctggt 2650

 gggaagcgtc tgtccgttta ctccaaggtg ggtctttgtg agagtgagct 2700

 gtaggtgtgc gggaccggta cagaaaggcg ttcttcgagg tggatcacag 2750

 aggcttcttc agatcaatgc ttgagtttgg aatcggccgc attccctgag 2800

 tcaccaggaa tgttaaagtc agtgggaacg tgactgcccc aactcctgga 2850

 agctgtgtcc ttgcacctgc atccgtagtt ccctgaaaac ccagagagga 2900

 atcagacttc acactgcaag agccttggtg tccacctggc cccatgtctc 2950

 tcagaattct tcaggtggaa aaacatctga aagccacgtt ccttactgca 3000

 gaatagcata tatatcgctt aatcttaaat ttattagata tgagttgttt 3050

 tcagactcag actccatttg tattatagtc taatatacag ggtagcaggt 3100

 accactgatt tggagatatt tatgggggga gaacttacat tgtgaaactt 3150

 ctgtacatta attattattg ctgttgttat tttacaaggg tctagggaga 3200

 gacccttgtt tgattttagc tgcagaactg tattggtcca gcttgctctt 3250

 cagtgggaga aaaacacttg taagttgcta aacgagtcaa tcccctcatt 3300

 caggaaaact gacagaggag ggcgtgactc acccaagcca tatataacta 3350

 gctagaagtg ggccaggaca ggccgggcgc ggtggctcac gcctgtaatc 3400

 ccagcagttt gggaggtcga ggtaggtgga tcacctgagg tcgggagttc 3450

 gagaccaacc tgaccaacat ggagaaaccc tgtctctatt aaaaatacaa 3500

 aaaaaaaaaa aaaaaaaaat agccgggcat ggtggcgcaa gcctgtaatc 3550

 ccagctactc aggaggctga ggcagaagaa ttgaacccag gaggtggagg 3600

 ttgcagtgag ctgagatcgt gccgttactc tccaacctgg acaacaagag 3650

 cgaaactccg tcttagaagt ggaccaggac aggaccagat tttggagtca 3700

 tggtccggtg tccttttcac tacaccatgt ttgagctcag acccccactc 3750

 tcattcccca ggtggctgac ccagtccctg ggggaagccc tggatttcag 3800

 aaagagccaa gtctggatct gggacccttt ccttccttcc ctggcttgta 3850

 actccaccaa gcccatcaga aggagaagga aggagactca cctctgcctc 3900

 aatgtgaatc agaccctacc ccaccacgat gtgccctggc tgctgggctc 3950

 tccacctcag gccttggata atgctgttgc ctcatctata acatgcattt 4000

 gtctttgtaa tgtcaccacc ttcccagctc tccctctggc cctgcttctt 4050

 cggggaactc ctgaaatatc agttactcag ccctgggccc caccacctag 4100

 gccactcctc caaaggaagt ctaggagctg ggaggaaaag aaaagagggg 4150

 aaaatgagtt tttatggggc tgaacgggga gaaaaggtca tcatcgattc 4200

 tactttagaa tgagagtgtg aaatagacat ttgtaaatgt aaaactttta 4250

 aggtatatca ttataactga aggagaaggt gccccaaaat gcaagatttt 4300

 ccacaagatt cccagagaca ggaaaatcct ctggctggct aactggaagc 4350

 atgtaggaga atccaagcga ggtcaacaga gaaggcagga atgtgtggca 4400

 gatttagtga aagctagaga tatggcagcg aaaggatgta aacagtgcct 4450

 gctgaatgat ttccaaagag aaaaaaagtt tgccagaagt ttgtcaagtc 4500

 aaccaatgta gaaagctttg cttatggtaa taaaaatggc tcatacttat 4550

 atagcactta ctttgtttgc aagtactgct gtaaataaat gctttatgca 4600

 aacc 4604

<210> 1106
<211> 427
<212> PRT
<213> Homo sapien

<400> 1106
 Met Glu Ala Met Ala Ala Ser Thr Ser Leu Pro Asp Pro Gly Asp
   1               5                  10                  15

 Phe Asp Arg Asn Val Pro Arg Ile Cys Gly Val Cys Gly Asp Arg
                  20                  25                  30

 Ala Thr Gly Phe His Phe Asn Ala Met Thr Cys Glu Gly Cys Lys
                  35                  40                  45

 Gly Phe Phe Arg Arg Ser Met Lys Arg Lys Ala Leu Phe Thr Cys
                  50                  55                  60

 Pro Phe Asn Gly Asp Cys Arg Ile Thr Lys Asp Asn Arg Arg His
                  65                  70                  75

 Cys Gln Ala Cys Arg Leu Lys Arg Cys Val Asp Ile Gly Met Met
                  80                  85                  90

 Lys Glu Phe Ile Leu Thr Asp Glu Glu Val Gln Arg Lys Arg Glu
                  95                 100                 105

 Met Ile Leu Lys Arg Lys Glu Glu Glu Ala Leu Lys Asp Ser Leu
                 110                 115                 120

 Arg Pro Lys Leu Ser Glu Glu Gln Gln Arg Ile Ile Ala Ile Leu
                 125                 130                 135

 Leu Asp Ala His His Lys Thr Tyr Asp Pro Thr Tyr Ser Asp Phe
                 140                 145                 150

 Cys Gln Phe Arg Pro Pro Val Arg Val Asn Asp Gly Gly Gly Ser
                 155                 160                 165

 His Pro Ser Arg Pro Asn Ser Arg His Thr Pro Ser Phe Ser Gly
                 170                 175                 180

 Asp Ser Ser Ser Ser Cys Ser Asp His Cys Ile Thr Ser Ser Asp
                 185                 190                 195

 Met Met Asp Ser Ser Ser Phe Ser Asn Leu Asp Leu Ser Glu Glu
                 200                 205                 210

 Asp Ser Asp Asp Pro Ser Val Thr Leu Glu Leu Ser Gln Leu Ser
                 215                 220                 225

 Met Leu Pro His Leu Ala Asp Leu Val Ser Tyr Ser Ile Gln Lys
                 230                 235                 240

 Val Ile Gly Phe Ala Lys Met Ile Pro Gly Phe Arg Asp Leu Thr
                 245                 250                 255

 Ser Glu Asp Gln Ile Val Leu Leu Lys Ser Ser Ala Ile Glu Val
                 260                 265                 270

 Ile Met Leu Arg Ser Asn Glu Ser Phe Thr Met Asp Asp Met Ser
                 275                 280                 285

 Trp Thr Cys Gly Asn Gln Asp Tyr Lys Tyr Arg Val Ser Asp Val
                 290                 295                 300

 Thr Lys Ala Gly His Ser Leu Glu Leu Ile Glu Pro Leu Ile Lys
                 305                 310                 315

 Phe Gln Val Gly Leu Lys Lys Leu Asn Leu His Glu Glu Glu His
                 320                 325                 330

 Val Leu Leu Met Ala Ile Cys Ile Val Ser Pro Asp Arg Pro Gly
                 335                 340                 345

 Val Gln Asp Ala Ala Leu Ile Glu Ala Ile Gln Asp Arg Leu Ser
                 350                 355                 360

 Asn Thr Leu Gln Thr Tyr Ile Arg Cys Arg His Pro Pro Pro Gly
                 365                 370                 375

 Ser His Leu Leu Tyr Ala Lys Met Ile Gln Lys Leu Ala Asp Leu
                 380                 385                 390

 Arg Ser Leu Asn Glu Glu His Ser Lys Gln Tyr Arg Cys Leu Ser
                 395                 400                 405

 Phe Gln Pro Glu Cys Ser Met Lys Leu Thr Pro Leu Val Leu Glu
                 410                 415                 420

 Val Phe Gly Asn Glu Ile Ser
                 425

<210> 1107
<211> 3045
<212> DNA
<213> Homo sapien

<400> 1107
 actaagaccg caaggcattc atttcctcct acggtggatg cggacgccgg 50

 gaggaggaga gccccagaga gaggagctgg gagcggaggc gcaggcaatg 100

 ctcagccctg gatgtagctg agaggctggg agaagagacg accgctggag 150

 accgagcggc gtggggaaga cctagggggg tgggtggggg aagcagacag 200

 gagaacactc gaaatcaagc gctttacaga ttattttatt ttgtatagag 250

 aacacgtagc gactccgaag atcagcccca atgaacatgt cagtgttgac 300

 tttacaagaa tatgaattcg aaaagcagtt caacgagaat gaagccatcc 350

 aatggatgca ggaaaactgg aagaaatctt tcctgttttc tgctctgtat 400

 gctgccttta tattcggtgg tcggcaccta atgaataaac gagcaaagtt 450

 tgaactgagg aagccattag tgctctggtc tctgaccctt gcagtcttca 500

 gtatattcgg tgctcttcga actggtgctt atatggtgta cattttgatg 550

 accaaaggcc tgaagcagtc agtttgtgac cagggttttt acaatggacc 600

 tgtcagcaaa ttctgggctt atgcatttgt gctaagcaaa gcacccgaac 650

 taggagatac aatattcatt attctgagga agcagaagct gatcttcctg 700

 cactggtatc accacatcac tgtgctcctg tactcttggt actcctacaa 750

 agacatggtt gccgggggag gttggttcat gactatgaac tatggcgtgc 800

 acgccgtgat gtactcttac tatgccttgc gggcggcagg tttccgagtc 850

 tcccggaagt ttgccatgtt catcaccttg tcccagatca ctcagatgct 900

 gatgggctgt gtggttaact acctggtctt ctgctggatg cagcatgacc 950

 agtgtcactc tcactttcag aacatcttct ggtcctcact catgtacctc 1000

 agctaccttg tgctcttctg ccatttcttc tttgaggcct acatcggcaa 1050

 aatgaggaaa acaacgaaag ctgaatagtg ttggaactga ggaggaagcc 1100

 atagctcagg gtcatcaaga aaaataatag acaaaagaaa atggcacaag 1150

 gaatcacacg tggtgcagct aaaacaaaac aaaacatgag caaacacaaa 1200

 acccaaggca gcttagggat aattaggttg atttaaccca gtaagtttat 1250

 gatcctttta gggtgaggac tcactgagtg cacctccatc tccaagcact 1300

 gctgctggaa gaccccattc cctctttatc tatcaactct aggacaaggg 1350

 agaacaaaag caagccagaa gcagaggaga ctaatcaaag gcaaacaaag 1400

 gctattaaca cataggaaaa tatgtattta ctaagtgtca catttctcta 1450

 agatgaaaga tttttactct agaaactgtg cgagcacaac acacacaatc 1500

 ctttctaact ttatggacac taaactggag ccaatagaaa agacaaaaat 1550

 gaaagagaca cagggtgtat atctagaacg ataatgcttt tgcagaaact 1600

 aaagcctttt taagaaatgc cagctgctgt agaccccatg agaaaagatg 1650

 tcttaatcat ccttatgaaa acagatgtaa acaactatat ttcaactaac 1700

 ttcatcttca ctgcatagcc tcaggctagt gagtttgcca aaaccaaagg 1750

 gggtgaatac ttccccaaga ttcttcctgg gaggatggaa acagtgcagc 1800

 ccaggtccca tgggggcagc tccatcccag agcatttctg atagttgaac 1850

 tgtaatttct actcttaagt gagatatgaa gtattatcct tttgttcagt 1900

 tgccccgggc ttttgaacag aagagtaaat acagaattga aaaagataaa 1950

 cactcaacca aacaatgtga aaacgggttc tgtagtattt gtaaaaaggc 2000

 ccggcccagg accactgtga gctggaaaag ggagaaaggc agtgggaaaa 2050

 gaggtgagcc gaagatcaat tcgacagaca gacggtgtgt atgcccctcc 2100

 ctgtttgact tcacacacac tcataacttt ccaaatgaaa ccccacagta 2150

 tagcgcatat tttcgatatt tttgtgaatt ccaaaaggaa atcacagggc 2200

 tgttcgaaat attgggggaa cactgtgttt ctgcatcatc tgcatttgct 2250

 ccccaagcaa tgtagaggtg tttaaagggc cctctgctgg ctgagtggca 2300

 atactacaac aaacttcaag gcaagtttgg ctgaaaacag ttgacaacaa 2350

 agggccccca tacacttatc cctcaaattt taagtgatat gaaatacttg 2400

 tcatgtcttt ggccaaatca gaagatattc atcctgcttc aagtcagctt 2450

 cagaaatgtt ttaaaaggga ctttagctct ggaactcaaa atcaatttat 2500

 taagagccat attctttaaa aaaaaaagct ggataatatt atctgtaata 2550

 tttcagtcct ttacaagcca aatacatgtg tcaatgtttc tagtatttca 2600

 aagaagcaat tatgtaaagt tgttcaatgt gacataatag tattataatt 2650

 ggttaagtag cttaatgatt aggcaaacta gatgaaaaga ttaggggctt 2700

 ccacactgca tagatcacac gcacatagcc acgcatacac acacagacac 2750

 acagatgtgg ggtacactga atttcaaagc ccaaatgaat agaaacacat 2800

 tttctggcta gcagaaaaaa acaaaacaaa actgttgttt ctctttcttg 2850

 ctttgagagt gtacagtaaa agggattttt tcgaattatt tttatattat 2900

 tttagcttta attgtgctgt cgttcatgaa acagagctgc tctgcttttc 2950

 tgtcagagat ggcaagggct ttttcagcat ctcgtttatg tgtggaattt 3000

 aaaaagaata aagttttatt ccattctgaa aaaaaaaaaa aaaaa 3045

<210> 1108
<211> 265
<212> PRT
<213> Homo sapien

<400> 1108
 Met Asn Met Ser Val Leu Thr Leu Gln Glu Tyr Glu Phe Glu Lys
   1               5                  10                  15

 Gln Phe Asn Glu Asn Glu Ala Ile Gln Trp Met Gln Glu Asn Trp
                  20                  25                  30

 Lys Lys Ser Phe Leu Phe Ser Ala Leu Tyr Ala Ala Phe Ile Phe
                  35                  40                  45

 Gly Gly Arg His Leu Met Asn Lys Arg Ala Lys Phe Glu Leu Arg
                  50                  55                  60

 Lys Pro Leu Val Leu Trp Ser Leu Thr Leu Ala Val Phe Ser Ile
                  65                  70                  75

 Phe Gly Ala Leu Arg Thr Gly Ala Tyr Met Val Tyr Ile Leu Met
                  80                  85                  90

 Thr Lys Gly Leu Lys Gln Ser Val Cys Asp Gln Gly Phe Tyr Asn
                  95                 100                 105

 Gly Pro Val Ser Lys Phe Trp Ala Tyr Ala Phe Val Leu Ser Lys
                 110                 115                 120

 Ala Pro Glu Leu Gly Asp Thr Ile Phe Ile Ile Leu Arg Lys Gln
                 125                 130                 135

 Lys Leu Ile Phe Leu His Trp Tyr His His Ile Thr Val Leu Leu
                 140                 145                 150

 Tyr Ser Trp Tyr Ser Tyr Lys Asp Met Val Ala Gly Gly Gly Trp
                 155                 160                 165

 Phe Met Thr Met Asn Tyr Gly Val His Ala Val Met Tyr Ser Tyr
                 170                 175                 180

 Tyr Ala Leu Arg Ala Ala Gly Phe Arg Val Ser Arg Lys Phe Ala
                 185                 190                 195

 Met Phe Ile Thr Leu Ser Gln Ile Thr Gln Met Leu Met Gly Cys
                 200                 205                 210

 Val Val Asn Tyr Leu Val Phe Cys Trp Met Gln His Asp Gln Cys
                 215                 220                 225

 His Ser His Phe Gln Asn Ile Phe Trp Ser Ser Leu Met Tyr Leu
                 230                 235                 240

 Ser Tyr Leu Val Leu Phe Cys His Phe Phe Phe Glu Ala Tyr Ile
                 245                 250                 255

 Gly Lys Met Arg Lys Thr Thr Lys Ala Glu
                 260                 265

<210> 1109
<211> 1885
<212> DNA
<213> Homo sapien

<400> 1109
 cgggcactca ccgtgtgtag ttggcatctc cgcgcgtccg gacacccgat 50

 cccagcatcc ctgcctgcag gactgttcgt gttcagctcg cgtcctgcag 100

 ctgtccgagg tgctccagtt ggaggctgag gttcccgggc tctgtcgctg 150

 agtgggcggc ggcaccggcg gagatgcctg ggaagaaggc gcgcaagaac 200

 gctcaaccga gccccgcgcg ggctccagca gagctggaag tcgagtgtgc 250

 tactcaactc aggagatttg gagacaaact gaacttccgg cagaaacttc 300

 tgaatctgat atccaaactc ttctgctcag gaacctgact gcatcaaaaa 350

 cttgcatgag gggactcctt caaaagagtt ttctcaggag gtgcacgttt 400

 catcaatttg aagaaagact gcattgtaat tgagaggaat gtgaaggtgc 450

 attcatgggt gcccttggaa acggaagatg gaatacatca aagtgaattt 500

 ctgttcaagt tttcccagat tatcattctt tgggatgaga gaacattata 550

 aaaccacttt gtttatttta aagcaagaat ggaagaccct tgaaaataaa 600

 gaagtaatta ttgacacatt tcttttttac ttagagaatc gttctagtgt 650

 ttttgccgaa gattaccgct ggcctactgt gaaggtagat gacctgtgat 700

 tagactgggc ggctggggag aaacagttca gtgcattgtt gttgttgctg 750

 tttttggtgt tttgcttttc agtgccaact cagcacattg tatatgattc 800

 ggtttataca tattaccttg ttataatgaa aaaactcatt ctgagaacac 850

 tgaaatgtta tactcagtgt tgatttcttc ggtcactaca caacgtaaaa 900

 tcatttgttt cttttgactc aaattgtatt gcttctgttc agatgatctt 950

 tcattcaatg tgttcctgtt gggcgttact agaaactatg gaaaactgga 1000

 aaataacttt gaaaaaattg gataaagtat aggagggtta cttggggcca 1050

 gtaaatcagt agactgaaca ttcaatataa taaaagaaca tggggatttt 1100

 gtataaccag ggataataaa aagaaaaaga agttaatttt taattgatgt 1150

 ttttgaaact tagtagaaca aatattcaga agtaacttga taagatatga 1200

 atgtttctaa agagtttcta aaggttcgaa atgctccttg tcacattagt 1250

 gtgcatccta caaaaagtga tctcttaatg taaattaaga atattttcat 1300

 aattggaata tacttttctt aaaaaaaagg aacagttagt tctcatctag 1350

 aatgaaagtt ccatatatgc attggtgaat atatatgtat acacatactt 1400

 acatacttat atgggtatct gtatagataa tttgtattag agtattatat 1450

 agcttcttag tagggtctca agtaagttca ttttttttat ctgggctata 1500

 tacagtcctc aaataaataa tgtcttgatt ttatttcagc aggaataatt 1550

 ttatttattt tgcctattta taattaaagt atttttcttt agtttgaaat 1600

 gtgtattaaa gttacatttt tgagttacaa gagtcttata actacttgaa 1650

 tttttagtta aaatgtctta atgtaggttg tagtcacttt agatggaaaa 1700

 ttacctcaca tctgttttct tcagtattac ttaagattgt ttatttagtg 1750

 gtagagagat tttttttttc agcctagagg cagctatttt accatctggt 1800

 atttatggtc taatttgtat ttaaacatat gcacacatat aaaagttgat 1850

 actgtggcag taaactatta aaagttttca ctgtt 1885

<210> 1110
<211> 54
<212> PRT
<213> Homo sapien

<400> 1110
 Met Pro Gly Lys Lys Ala Arg Lys Asn Ala Gln Pro Ser Pro Ala
   1               5                  10                  15

 Arg Ala Pro Ala Glu Leu Glu Val Glu Cys Ala Thr Gln Leu Arg
                  20                  25                  30

 Arg Phe Gly Asp Lys Leu Asn Phe Arg Gln Lys Leu Leu Asn Leu
                  35                  40                  45

 Ile Ser Lys Leu Phe Cys Ser Gly Thr
                  50

<210> 1111
<211> 1885
<212> DNA
<213> Homo sapien

<400> 1111
 cgggcactca ccgtgtgtag ttggcatctc cgcgcgtccg gacacccgat 50

 cccagcatcc ctgcctgcag gactgttcgt gttcagctcg cgtcctgcag 100

 ctgtccgagg tgctccagtt ggaggctgag gttcccgggc tctgtcgctg 150

 agtgggcggc ggcaccggcg gagatgcctg ggaagaaggc gcgcaagaac 200

 gctcaaccga gccccgcgcg ggctccagca gagctggaag tcgagtgtgc 250

 tactcaactc aggagatttg gagacaaact gaacttccgg cagaaacttc 300

 tgaatctgat atccaaactc ttctgctcag gaacctgact gcatcaaaaa 350

 cttgcatgag gggactcctt caaaagagtt ttctcaggag gtgcacgttt 400

 catcaatttg aagaaagact gcattgtaat tgagaggaat gtgaaggtgc 450

 attcatgggt gcccttggaa acggaagatg gaatacatca aagtgaattt 500

 ctgttcaagt tttcccagat tatcattctt tgggatgaga gaacattata 550

 aaaccacttt gtttatttta aagcaagaat ggaagaccct tgaaaataaa 600

 gaagtaatta ttgacacatt tcttttttac ttagagaatc gttctagtgt 650

 ttttgccgaa gattaccgct ggcctactgt gaaggtagat gacctgtgat 700

 tagactgggc ggctggggag aaacagttca gtgcattgtt gttgttgctg 750

 tttttggtgt tttgcttttc agtgccaact cagcacattg tatatgattc 800

 ggtttataca tattaccttg ttataatgaa aaaactcatt ctgagaacac 850

 tgaaatgtta tactcagtgt tgatttcttc ggtcactaca caacgtaaaa 900

 tcatttgttt cttttgactc aaattgtatt gcttctgttc agatgatctt 950

 tcattcaatg tgttcctgtt gggcgttact agaaactatg gaaaactgga 1000

 aaataacttt gaaaaaattg gataaagtat aggagggtta cttggggcca 1050

 gtaaatcagt agactgaaca ttcaatataa taaaagaaca tggggatttt 1100

 gtataaccag ggataataaa aagaaaaaga agttaatttt taattgatgt 1150

 ttttgaaact tagtagaaca aatattcaga agtaacttga taagatatga 1200

 atgtttctaa agagtttcta aaggttcgaa atgctccttg tcacattagt 1250

 gtgcatccta caaaaagtga tctcttaatg taaattaaga atattttcat 1300

 aattggaata tacttttctt aaaaaaaagg aacagttagt tctcatctag 1350

 aatgaaagtt ccatatatgc attggtgaat atatatgtat acacatactt 1400

 acatacttat atgggtatct gtatagataa tttgtattag agtattatat 1450

 agcttcttag tagggtctca agtaagttca ttttttttat ctgggctata 1500

 tacagtcctc aaataaataa tgtcttgatt ttatttcagc aggaataatt 1550

 ttatttattt tgcctattta taattaaagt atttttcttt agtttgaaat 1600

 gtgtattaaa gttacatttt tgagttacaa gagtcttata actacttgaa 1650

 tttttagtta aaatgtctta atgtaggttg tagtcacttt agatggaaaa 1700

 ttacctcaca tctgttttct tcagtattac ttaagattgt ttatttagtg 1750

 gtagagagat tttttttttc agcctagagg cagctatttt accatctggt 1800

 atttatggtc taatttgtat ttaaacatat gcacacatat aaaagttgat 1850

 actgtggcag taaactatta aaagttttca ctgtt 1885

<210> 1112
<211> 54
<212> PRT
<213> Homo sapien

<400> 1112
 Met Pro Gly Lys Lys Ala Arg Lys Asn Ala Gln Pro Ser Pro Ala
   1               5                  10                  15

 Arg Ala Pro Ala Glu Leu Glu Val Glu Cys Ala Thr Gln Leu Arg
                  20                  25                  30

 Arg Phe Gly Asp Lys Leu Asn Phe Arg Gln Lys Leu Leu Asn Leu
                  35                  40                  45

 Ile Ser Lys Leu Phe Cys Ser Gly Thr
                  50

<210> 1113
<211> 664
<212> DNA
<213> Homo sapien

<400> 1113
 ggattgttgg tctgcgtgga acttctcagg tggacaccag agcatggaac 50

 acatccacga cagcgatggc agttccagca gcagccacca gagcctcaag 100

 agcacagcca aatgggcggc atccctggag aatctgctgg aagacccaga 150

 aggcgtgaaa agatttaggg aatttttaaa aaaggaattc agtgaagaaa 200

 atgttttgtt ttggctagca tgtgaagatt ttaagaaaat gcaagataag 250

 acgcagatgc aggaaaaggc aaaggagatc tacatgacct ttctgtccag 300

 caaggcctca tcacaggtca acgtggaggg gcagtctcgg ctcaacgaga 350

 agatcctgga agaaccgcac cctctgatgt tccagaaact ccaggaccag 400

 atctttaatc tcatgaagta cgacagctac agccgctttc ttaagtctga 450

 cttgttttta aaacacaagc gaaccgagga agaggaagaa gatttgcctg 500

 atgctcaaac tgcagctaaa agagcttcca gaatttataa cacatgagcc 550

 cccaaaaagc cgggactggc agctttaaga agcaaaggaa tttcctctca 600

 ggacgtgccg ggtttatcat tgctttgtta tttgtaagga ctgaaatgta 650

 caaaaccctt caat 664

<210> 1114
<211> 167
<212> PRT
<213> Homo sapien

<400> 1114
 Met Glu His Ile His Asp Ser Asp Gly Ser Ser Ser Ser Ser His
   1               5                  10                  15

 Gln Ser Leu Lys Ser Thr Ala Lys Trp Ala Ala Ser Leu Glu Asn
                  20                  25                  30

 Leu Leu Glu Asp Pro Glu Gly Val Lys Arg Phe Arg Glu Phe Leu
                  35                  40                  45

 Lys Lys Glu Phe Ser Glu Glu Asn Val Leu Phe Trp Leu Ala Cys
                  50                  55                  60

 Glu Asp Phe Lys Lys Met Gln Asp Lys Thr Gln Met Gln Glu Lys
                  65                  70                  75

 Ala Lys Glu Ile Tyr Met Thr Phe Leu Ser Ser Lys Ala Ser Ser
                  80                  85                  90

 Gln Val Asn Val Glu Gly Gln Ser Arg Leu Asn Glu Lys Ile Leu
                  95                 100                 105

 Glu Glu Pro His Pro Leu Met Phe Gln Lys Leu Gln Asp Gln Ile
                 110                 115                 120

 Phe Asn Leu Met Lys Tyr Asp Ser Tyr Ser Arg Phe Leu Lys Ser
                 125                 130                 135

 Asp Leu Phe Leu Lys His Lys Arg Thr Glu Glu Glu Glu Glu Asp
                 140                 145                 150

 Leu Pro Asp Ala Gln Thr Ala Ala Lys Arg Ala Ser Arg Ile Tyr
                 155                 160                 165

 Asn Thr


<210> 1115
<211> 415
<212> DNA
<213> Homo sapien

<400> 1115
 ccgctgcgtg ttttcctctt gatcgggaac tcctgcttct ccttgcctcg 50

 aaatggaccc caactgctcc tgctcgcctg ttggctcctg tgcctgtgcc 100

 ggctcctgca aatgcaaaga gtgcaaatgc acctcctgca agaagagctg 150

 ctgctcctgc tgccctgtgg gctgtgcmaa gtgtgcccag ggctgcatct 200

 gcaaagggac gtcagacaag tgcagctgct gtgcctgatg ccaggacagc 250

 tgtgctctca gatgtaaata gagcaaccta tataaacctg gatttttttt 300

 tttttttttt tgtacaaccc tgacccgttt gctacatctt tttttctatg 350

 aaatatgtga atggcaataa attcatctag actaaaaaaa aaaaaaaaaa 400

 aaaaaaaaaa aaaaa 415

<210> 1116
<211> 61
<212> PRT
<213> Homo sapien

<400> 1116
 Met Asp Pro Asn Cys Ser Cys Ser Pro Val Gly Ser Cys Ala Cys
   1               5                  10                  15

 Ala Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ala Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Ile Cys Lys Gly Thr Ser Asp Lys Cys Ser Cys Cys
                  50                  55                  60

 Ala


<210> 1117
<211> 439
<212> DNA
<213> Homo sapien

<400> 1117
 ggtgggtctg aatctagcac catgacggaa ctagagacag ccatgggcat 50

 gatcatagac gtcttttccc gatattcggg cagcgagggc agcacgcaga 100

 ccctgaccaa gggggagctc aaggtgctga tggagaagga gctaccaggc 150

 ttcctgcaga gtggaaaaga caaggatgcc gtggataaat tgctcaagga 200

 cctggacgcc aatggagatg cccaggtgga cttcagtgag ttcatcgtgt 250

 tcgtggctgc aatcacgtct gcctgtcaca agtactttga gaaggcagga 300

 ctcaaatgat gccctggaga tgtcacagat tcctgcagag ccatggtccc 350

 aggcttccca aaagtgtttg ttggcaatta ttcccctagg ctgagcctgc 400

 tcatgtacct ctgattaata aatgcttatg aaaaaaaaa 439

<210> 1118
<211> 95
<212> PRT
<213> Homo sapien

<400> 1118
 Met Thr Glu Leu Glu Thr Ala Met Gly Met Ile Ile Asp Val Phe
   1               5                  10                  15

 Ser Arg Tyr Ser Gly Ser Glu Gly Ser Thr Gln Thr Leu Thr Lys
                  20                  25                  30

 Gly Glu Leu Lys Val Leu Met Glu Lys Glu Leu Pro Gly Phe Leu
                  35                  40                  45

 Gln Ser Gly Lys Asp Lys Asp Ala Val Asp Lys Leu Leu Lys Asp
                  50                  55                  60

 Leu Asp Ala Asn Gly Asp Ala Gln Val Asp Phe Ser Glu Phe Ile
                  65                  70                  75

 Val Phe Val Ala Ala Ile Thr Ser Ala Cys His Lys Tyr Phe Glu
                  80                  85                  90

 Lys Ala Gly Leu Lys
                  95

<210> 1119
<211> 11740
<212> DNA
<213> Homo sapien

<400> 1119
 cccggagccg gtgcgaggag ggcacccggt gcgtccccgg agcggggagg 50

 ccaggccggg caaccctggg gccggtcggg gcggcgtcac tgcaccctcc 100

 gccaggctcc gcgggatgca ccgtggtagc cgagggcgga ggcgacactc 150

 tcaggtaaat tggcaggatg aggagcagca aatcaaaaga ggtgccttta 200

 ccaaatccaa ggaactctca aagcaaggat actgttcaag cagatataac 250

 cacatcgtgg gatgcacttt ctcaaaccaa ggctgctctg agacacattg 300

 aaaataaatt agaagtagcc cctacaagta cagctgtgtg tgattctgtc 350

 atggatacca agaagtcttc tacaagtgct actcgaaaaa taagtagaaa 400

 agatggtaga tacctggatg attcttgggt taatgctcca atctccaaat 450

 ccactaaatc acgaaaagag aaatctcgta gtcctctcag ggccaccacc 500

 ctggagggta atgtgaagaa aaataatcgt gtggaatttc gtgaaccttt 550

 ggtttcttat agggaaatcc atggtgcacc ttccaatttc agttccagcc 600

 atctggaatc aaagcacgta tactgtgtag atgttaatga agaaaagact 650

 gagagcggta actggatgat aggcagtcga gaagaacgga atatacggag 700

 ctgtgatttt gagagctccc aatcatctgt catcaatgat acagttgtta 750

 ggtttttaaa tgatcgacca gcaattgatg cattgcaaaa ttctgaatgt 800

 ttgattagga tgggagcttc tatgagaact gaggaagaaa tgcctaacag 850

 aacaaaagga agtgagaata atttgaagct ttctgtgaat aacatggccc 900

 atgatactga tccaaaagcg ttacgactaa ctgactcttc tccatcctct 950

 actagtactt ctaattccca aagattagat attctaaagc ggcgacaaca 1000

 tgatgtcaaa ctggaaaaac ttaaggaacg gattagaaaa cagtgggaac 1050

 actcagaaga aacaaatggc cggggccaga agctgggtca tattgaccat 1100

 ccagtaatgg ttgttaatgt tgataactca gtaacagcaa aagtcagaaa 1150

 agtggcaaca gcaccacctg ctccagcata taaaggtttc aacccttcag 1200

 agaccaagat tcgaacacct gatgggaaag tgtggcagga ggctgagttt 1250

 caaaacatga gtagagaact gtatcgagat ttagcacttc actttgcaga 1300

 tgatatttct ataaaggaga aacctgctga aaaaagtaaa gagaagaaag 1350

 tagtcaagcc agtacgaaaa gtccaaaaag tagcacagtt atcaagtaca 1400

 gaatgcagaa caggtagtag tcatcttata agtacatctt cttggcgaga 1450

 tggacaaaaa ttagtaaaga agattctggg acctgctccc agaatggagc 1500

 caaaagagca aagaacagca tcaagtgaca gaggtggaag aagaagaact 1550

 gctaaatctg ggggtcacat tggaagagca gaatctgatc ccaggttgga 1600

 cgttttacat agacatcttc aaagaaactc agaacgttcg agaagtaaat 1650

 ctcggtctga aaataatata aagaaactag cttcatctct tccagataat 1700

 aagcaggagg aaaatactgc cttaaataag gactttttac ctattgaaat 1750

 tcgtggcatt cttgatgacc tacagctgga ttctacagct cacactgcaa 1800

 agcaagatac tgtagagtta cagaaccaga agtcatcagc accagtacat 1850

 gctcctagga gtcacagccc agtaaaaaga aaacctgaca aaataacagc 1900

 taatgaagat ccccctgtta tttccaaaag gcgccactat gacacagatg 1950

 aggtacgaca gtacattgtt aggcagcagg aggaaaggaa gagaaagcaa 2000

 aatgaagaga agaaggctca aaaggaggct acagaacaga aaaacaaacg 2050

 attacaagag ctctaccgga agcagaagga agcctttact aaagtaaaaa 2100

 atgtccctcc ttctgagcca tcagcaacta ggcgactaca ggaaacttac 2150

 tccaaattgc tactagaaaa gaccttgctt gaagagccat ctcatcaaca 2200

 tgttacgcag gaaacacagg ccaaaccagg gtatcagcca tctggagaat 2250

 ctgacaaaga aaacaaagta caggaacgtc ccccaagtgc atcttccagt 2300

 agtgacatgt ctctctcaga acctccacag cctcttgcaa gaaaagactt 2350

 gatggaatct acatggatgc agcctgaaag attgagccca caagttcacc 2400

 attctcaacc acagcctttt gctggaacag ctggaagttt actctcccat 2450

 ctcttgagtt tagagcatgt aggaattttg cataaggatt ttgaatctat 2500

 tttaccaacc aggaagaatc ataatatggc ttcaaggcca ttaactttta 2550

 cacctcaacc atatgtgacc tcaccagctg cttatacaga tgccttgtta 2600

 aaacctagtg ccagccaata taagagtaaa ctggatcgta ttgaagcctt 2650

 gaaagcaaca gctgcttctt tgtccagcag aattgaaagt gaagccaaga 2700

 aattagctgg ggccagcatt aactatgggt cagcatggaa cactgagtat 2750

 gatgtgcagc aggcacctca agaagatgga ccttggacca aggctgtaac 2800

 tccacctgtg aaagatgata atgaagatgt tttctctgcc agaattcaga 2850

 agatgctggg aagctgtgta tctcatgcaa cttttgatga tgatcttcct 2900

 ggtgtaggca atcttagtga atttaaaaag cttcctgaga tgataagacc 2950

 acagagtgcc atatcaagct ttagagtgag atcccctggt cccaaaccac 3000

 aagggctact ggcacagtta tgtaaaaggc agactgactc ttctagctct 3050

 gatatgcaag cctgttctca agacaaagcc aaaatatctc ttggttccag 3100

 catagattca gtcagtgaag ggcctcttct tagtgagggg agtctctctg 3150

 aagaagaggg agaccaggat ggacagcccc ttttgaaagt agcagaaatt 3200

 ttaaaagaaa aggaattttg tcctggagaa agaaatagtt atgaacccat 3250

 caaagagttt cagaaagaag ctgaaaaatt cttgccactt tttgggcaca 3300

 taggtggtac acaaagcaaa ggaccatggg aagaattggc aaagggaagt 3350

 ccacatagcg tcattaatat ttttacaaaa tcctatcagt tatatggaaa 3400

 agggtttgaa gacaagttgg acagaggaac atcaacatca cggcctttga 3450

 atgccaccgc aactcctcta agtggtgttt catatgaaga tgattttgtc 3500

 tcctctccag ggactgggac ttcgacagaa aaaaaatcaa ctcttgaacc 3550

 tcatagcact ttaagccctc aggaggacca ttctaacaga aagtctgcct 3600

 atgatccttc ctctgtggat gttacctccc agcattcatc aggagcccag 3650

 tctgctgcat cgtctcgttc atctacttct tctaaaggaa agaaaggaaa 3700

 aaaggaaaag acagaatggt tggattcatt cactggaaat gttcagaact 3750

 cacttcttga tgaggaaaaa gcagaacgtg gctcccatca aggaaagaaa 3800

 tctgggacca gcagcaaact ttctgttaaa gattttgagc agactcttga 3850

 tacagatagc actttggagg atctttctgg acattctgtg agtgtctcat 3900

 cagataaggg aagatctcag aaaactccaa cttctcccct gtcaccaagt 3950

 tcccagaaat cattgcagtt tgacgttgca ggaacttctt cagaaagatc 4000

 taagtcgtca gtaatgcctc caactataac aggatttaag cctaatgcac 4050

 ctctcactga tctgaacccg gcagccagca gaacaacgac agagaacatg 4100

 gctccaatac caggttctaa gcgcttttct cctgctggcc tccatcatcg 4150

 tatggcagca gaactcagtt atctgaacgc cattgaggag tcggtgcgcc 4200

 aactgtcaga tgtagaaaga gttagaggca tttcacttgc tcagcaggag 4250

 agtgtgtctc tagctcagat aataaaggca caacagcaac gccatgaaag 4300

 agacttggcc ctcttgaaac taaaggctga acaagaggct ctggagagtc 4350

 agagacaatt agaagaaacc cgaaacaaag cagctcaggt ccatgcagaa 4400

 tcattacagc aggtggttca atcacaacgg gaagtaactg aagtcctgca 4450

 ggaagcaacg tgtaaaatag cagctcagca gtcagaaact gctcgcctca 4500

 ccacagacgc agcacgtcaa atctgtgaga tggcagagtt gactagaact 4550

 catatctcag atgctgtcgt ggcttcagga gctccccttg caatactgta 4600

 tgaccaccaa cggcagcacc ttccagactt tgtgaaacag ctgaggacca 4650

 gaactgaaac agataggaaa agtccatctg tttcactctc tcagagtaaa 4700

 gaagggaccc ttgactcaaa gcatcagaag tattctgctt catatgatag 4750

 ttattctgag tcttcaggat acaagaatca tgatagaaga agtagcagtg 4800

 gtagcagccg ccaagaaagt ccttcagttc catcttgtaa ggaaaatgag 4850

 aagaaactta atggtgaaaa gatagagagt tccattgatg aacaggttca 4900

 gactgctgca gatgattctc tacgaagtga tagtgttcca tctcttcctg 4950

 atgaaaaaga ctcaacgtct attgcaacag aatattctct gaaatttgat 5000

 gaatccatga cagaagatga aatagaagaa caatcatttc gatcattact 5050

 accttcagag agtcaccgca gatttaacat ggaaaagaga agaggtcatc 5100

 atgatgactc tgatgaagaa gcttctccag aaaaaactac actgtctact 5150

 gccaaggaac tgaacatgcc attctcagga ggacaagata gcttttctaa 5200

 atttactatg gagatggttc gacagtatat gaaagaggaa gaaatgaggg 5250

 cagctcacca gtcttcactc ctgcgtctcc gtgaaaaggc cttgaaggag 5300

 aagactaagg ctgaattggc ctggttagag catcaaaaaa aacatctacg 5350

 agacaaagga gaggatgata aaatgccccc gctccggaag aaacagcgtg 5400

 gtttgctttt aaggttgcag caagaaaagg cagaaataaa acgtcttcaa 5450

 gaagccaata aggcagctcg gaaggaaaga cagctgattc ttaaacagca 5500

 ggaggagata gaaaagatcc gacagaccac cataaaacta caggagaaat 5550

 tgaagtctgc aggggagagt aaattggact ctcatagtga tgatgataca 5600

 aaggataata aggcaaccag tcctggtcca actgacttgg agacccgcag 5650

 tccttctccc atttcaatct ccagcagtga aactagcagc attatgcaga 5700

 aactgaagaa aatgagaagc cgcatggatg aaaagtttct gacaaagcgg 5750

 gagcaaaaat taatgcaacg gcgacaacat gcagaggagc tcctagagtg 5800

 gaagcgacgt ttagatgcag aagaagcaga aattcgtcaa atggaaaaac 5850

 aagctttggc tgcctgggac aaagaattaa taaaacccaa aactcctaag 5900

 aaagaactgg aggaccagag aacagaacag aaagaaatag caagtgaaga 5950

 ggaatctcca gtacctctgt actctcatct aaacagtgaa agctccattc 6000

 cagaagaatt aggcagccct gctgttgaat atgtaccatc cgagtctata 6050

 ggacaggagc agccagggag tccagatcac agtatactta ctgaagaaat 6100

 gatttgttca caggaactag aatcttctac ctctcctagt aaacattcac 6150

 ttcccaaaag ctgcacatct gtgtcaaagc aggagtctag caaaggaagt 6200

 cataggactg gaggacaatg tcacctgcct atcaagtccc atcagcactg 6250

 ttatagttgg tcagatgagt cattatctat gacacagtca gaaactacat 6300

 ctgaccagag tgatattgaa ggtaggatca gagctctgaa ggatgagttg 6350

 cggaaaagaa aatcagttgt gaaccagctg aagaaggaac agaaaaaaag 6400

 gcaaaaggaa agactgaaag cccaagaagc cagtctgatc aagcagttag 6450

 agtcatatga tgaatttatt aagaaaactg aagccgagct tagccaagat 6500

 ttggaaacat caccaacagc caagcctcag attaaaacgc tctcctcagc 6550

 ttctgaaaaa cccaagatca aacccctcac accactacac agatctgaaa 6600

 cggcaaagaa ttggaaatca ctaacagagt cagaacgttc cagaggatcc 6650

 ctggagccta ttgctgaaca tgttgatgct tcactgtctg gttctgagag 6700

 atcagtatca gaaaggtctt tatctgcata tgcaaagaga gtaaatgaat 6750

 gggacagtcg aacagaagat tttcagaccc catctccagt tctcagatca 6800

 tcaaggaaaa tcagagaaga atctggagat tctctagaaa atgtacctgc 6850

 attacatctt ctcaaagaat taaatgccac tagtagaatt cttgatatgt 6900

 cagatggcaa ggttggagaa tctagtaaaa aatcagaaat aaaagaaata 6950

 gagtatacaa aattgaagaa gagtaagatt gaagatgcct tttctaaaga 7000

 aggtaaatct gatgtcttac tgaaattagt cctagaacag ggagattcat 7050

 ctgaaattct ttcaaagaaa gatcttcctt tagattctga aaatgttcag 7100

 aaagacctag ttggattagc tattgaaaat ctccataaaa gtgaggaaat 7150

 gttgaaagag agacagtcag atcaagatat gaatcatagt ccaaacatcc 7200

 aatcaggaaa agacattcac gaacaaaaga acacaaagga aaaagatttg 7250

 tcttggtcag aacatctttt tgctcctaaa gagataccat actctgaaga 7300

 ttttgaagtg tcttctttca agaaagaaat ttcagctgaa ttgtacaaag 7350

 atgattttga ggtgtcatct ttgctgtcac tcaggaaaga ctctcagtct 7400

 tgcagagata agccacagcc aatgaggagc tctacaagtg gagccactag 7450

 ctttggtagt aatgaggaaa tcagtgagtg cctaagtgag aaaagccttt 7500

 ctatccatag caatgttcat tctgacaggc tgttggaact caagtcccct 7550

 actgagctga tgaaaagtaa ggagcgcagt gatgtggagc atgaacagca 7600

 agttactgaa tccccttcct tggcttcagt tcctactgca gacgagttat 7650

 ttgatttcca cattggtgat agggtgttga ttggaaatgt tcagccagga 7700

 attcttcgat tcaaaggtga gactagtttt gctaaaggat tttgggccgg 7750

 agtggagtta gataaacctg aaggaaataa caatggaaca tatgatggta 7800

 ttgcatattt tgagtgcaaa gaaaagcatg gtatttttgc tcctcctcaa 7850

 aaaatatctc acattccaga aaactttgat gactatgtag acattaatga 7900

 agatgaagac tgttactcag atgaacgata tcagtgctat aatcaagagc 7950

 aaaatgatac agagggtcca aaagacagag aaaaggatgt cagtgaatat 8000

 ttttatgaga aatccctacc tagtgtgaat gatatagaag cctcagttaa 8050

 tagaagtaga agccttaaaa tagaaacaga caatgtacag gacatttctg 8100

 gggtacttga agcccatgtt caccagcagt cttcagtgga ttcacagatt 8150

 tcttcaaagg aaaacaaaga cctcatttct gatgccacag aaaaggtttc 8200

 catcgctgca gaagatgaca ctttagacaa taccttttcc gaagaattgg 8250

 agaagcaaca gcagtttaca gaagaggaag acaacctata tgctgaagct 8300

 tcagaaaagc tttgtacacc acttctggat cttttaacaa gagaaaaaaa 8350

 ccaactggaa gcccagctga agtcatcact aaatgaggaa aaaaagtcaa 8400

 aacaacaact ggaaaaaatc agcttactga cagacagttt actaaaagtc 8450

 tttgtaaagg acacagtcaa tcaactacaa caaatcaaaa aaaccaggga 8500

 tgagaaaatc cagcttagca atcaggagct tcttggtgat gaccaaaaga 8550

 aagtaacacc ccaagaccta tcccaaaatg ttgaggaaca gtcgccaagt 8600

 atttcaggtt gcttcttaag ttctgaattg gaagatgaaa aagaagagat 8650

 ttcctctcca gatatgtgtc ccagaccgga gagcccagta tttggtgcca 8700

 gtgggcagga agaacttgct aagagacttg ctgaacttga actcagccgg 8750

 gagttcctga gcgcgttagg agatgatcaa gactggtttg atgaagactt 8800

 tggtttgagc tcttctcaca agatccaaaa aaataaggca gaagaaacca 8850

 ttgtacctct aatggcagaa cctaaaagag taacccaaca accatgtgaa 8900

 acattattgg cagtccccca tactgcagaa gaagtagaga ttcttgtaca 8950

 taatgcagca gaagaacttt ggaaatggaa agaattaggc cacgatcttc 9000

 atagcatcag tattcctaca aaactgcttg gctgtgccag taaaggtcta 9050

 gatatagaaa gcactagtaa aagggtctac aaacaggcgg tttttgattt 9100

 aacaaaagag atttttgagg aaatatttgc tgaggatccc aacttaaatc 9150

 aacctgtctg gatgaagcca tgtagaatca actctagtta tttccgacga 9200

 gtgaaaaatc caaataacct tgatgaaatc aagagcttca tagcaagtga 9250

 agtactcaag ttgttcagtc ttaaaaagga gccaaaccac aaaacagatt 9300

 ggcagaaaat gatgaaattt ggaagaaaga aaagagaccg agtggatcat 9350

 atcctggttc aggagctcca tgaggaggag gcacagtggg tgaactatga 9400

 tgaggatgag ttgtgtgtga aaatgcagct agccgacggg atctttgaga 9450

 ccctgatcaa agatactatt gatgttctga atcagatcag tgaaaagcag 9500

 gggagaatgc tactagtgtg acatcttgca aataaatcga acgctgagtg 9550

 ctaatgtgag tcctgggcct ttctgcctcc tgatgtacac ccatcgccat 9600

 catagcaaga gtgcttctgg accttgtact tattcttaaa gactaccagt 9650

 atggagttca taggacaatg tggtacacct ggtattacag cctttgcctt 9700

 tcgagactat ccactggatt aatgggttat tttcagtggg cagggttgca 9750

 cagtgtaatc ctacaccttt tgctaacacc cctactaggt cccagagggc 9800

 cagaaacacc tgacttacct ctgagtttag actagggtat cacttctttg 9850

 agtctgaagt caagtgagag aggtatagat aaatgcatca catcactttt 9900

 gaaatgtaat tctggtctat accatggaag tcataaatgg acattatagt 9950

 ctctaaacag tattaaaccc ttaaccactt ctaaaatagg caagctcaat 10000

 aatgtctgcc aacttcacat tctggagttt atttcatttc tttttgaaga 10050

 ccattttctt ccattattgt agttgagcag caccaagtgg actgtcaggc 10100

 taacaggaat aagtggtagc cttgctttct gagcaccatc taaagaattt 10150

 taaacctctg cattatgttt agtgttctct gtgtgggcat gaaaacaaag 10200

 aaatgcccct actgaagact gggctcaaag gaccaatgca gggctggttc 10250

 ttttacccct tggtttactc ctgcacttgt cttactcatt ctgaatctct 10300

 accagctgct cccagaatca cagatactca ggaccatctc aggcatccag 10350

 gcatggcaaa gtggaaataa ttcattttgg cctgcaaacc ttcaactccc 10400

 atctttcccc aagaagtcag agatgctgtt acttgaatga tttaggaaat 10450

 gagtgtgtgc accaaagaca aaaagatatt gtctattgtt tgtgtgcttg 10500

 ttttgcgcta tggaacattt tttaatttat tttaagataa attattaagt 10550

 tgaaaatgtg tgtccctatt cagaagtgaa agattcatct tgtaatagtt 10600

 aaacctccat cttgaagctt ctatggttca tagtctttgc acaggaacct 10650

 gtggttttaa caaaccaata cacatattga agaagtcatt ttaattcagt 10700

 gaaacgaaga tgggcttttc cagatcacct gcaatagcag cagtgggata 10750

 aaatgattta aaaacactgt acaatttaac tctgcctctc ttgcagcatt 10800

 gcttctcaca actattacct gcatctgaaa aaaaatctat agactccagc 10850

 tgctacatta gagcataaga gatgctctcc tgggacctca gtaccctgcc 10900

 ttcttgactg gtttccgttc atcagtcctg tccctcttca agtaatctag 10950

 aagaatgtgg atactcttag gcgtgaatgt aaatgcctta atattgaagg 11000

 tcctggttag aagcatgata caagacatct actggattca tatttacaaa 11050

 tatcctggaa tgttatagct tcaaagtata ttagaaaaac cccaaagatg 11100

 gtataatctt taagtgtgca cgttcgttta tttctgcatc ttccctccaa 11150

 acttgccttt gcatcttaaa tatttcacta tgcacactcc cattcctctt 11200

 gggtttcatc ttgtcgttta agaaatgtac tgaaataatc attggaatat 11250

 ttgcattttg cacaatgact ggtatgatag ctcttgacaa ataaggaaag 11300

 cactgaaatg ttgtgattgg gtctcgggaa atgctcagat tgatgtctta 11350

 ccagcatttc ttctgggctt gtgatgttga gctgtagtct tgtagccata 11400

 atgagcaaat tgactaagag aagcaaaggt ttcttggggt tattaaccag 11450

 tagtgtggaa atactagttt tatgtggcca aggaaaagca aagccttttc 11500

 ttttcagttt gtgttatttg gaagacagaa aaacatcttg tctacatcct 11550

 ttggctgttt gtaggatcac gttgtcctta cgatactgaa actttacagc 11600

 tgctgtaaat tttttataaa tgaatttcaa aatgttataa tgggactgta 11650

 ggttgttttt ctacatcttc attatttgga cctaaaacca gtttttaata 11700

 agaaagttta tctttactct ttctgaaatt atgactccag 11740

<210> 1120
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1120
 Met Arg Ser Ser Lys Ser Lys Glu Val Pro Leu Pro Asn Pro Arg
   1               5                  10                  15

 Asn Ser Gln Ser Lys Asp Thr Val Gln Ala Asp Ile Thr Thr Ser
                  20                  25                  30

 Trp Asp Ala Leu Ser Gln Thr Lys Ala Ala Leu Arg His Ile Glu
                  35                  40                  45

 Asn Lys Leu Glu Val Ala Pro Thr Ser Thr Ala Val Cys Asp Ser
                  50                  55                  60

 Val Met Asp Thr Lys Lys Ser Ser Thr Ser Ala Thr Arg Lys Ile
                  65                  70                  75

 Ser Arg Lys Asp Gly Arg Tyr Leu Asp Asp Ser Trp Val Asn Ala
                  80                  85                  90

 Pro Ile Ser Lys Ser Thr Lys Ser Arg Lys Glu Lys Ser Arg Ser
                  95                 100                 105

 Pro Leu Arg Ala Thr Thr Leu Glu Gly Asn Val Lys Lys Asn Asn
                 110                 115                 120

 Arg Val Glu Phe Arg Glu Pro Leu Val Ser Tyr Arg Glu Ile His
                 125                 130                 135

 Gly Ala Pro Ser Asn Phe Ser Ser Ser His Leu Glu Ser Lys His
                 140                 145                 150

 Val Tyr Cys Val Asp Val Asn Glu Glu Lys Thr Glu Ser Gly Asn
                 155                 160                 165

 Trp Met Ile Gly Ser Arg Glu Glu Arg Asn Ile Arg Ser Cys Asp
                 170                 175                 180

 Phe Glu Ser Ser Gln Ser Ser Val Ile Asn Asp Thr Val Val Arg
                 185                 190                 195

 Phe Leu Asn Asp Arg Pro Ala Ile Asp Ala Leu Gln Asn Ser Glu
                 200                 205                 210

 Cys Leu Ile Arg Met Gly Ala Ser Met Arg Thr Glu Glu Glu Met
                 215                 220                 225

 Pro Asn Arg Thr Lys Gly Ser Glu Asn Asn Leu Lys Leu Ser Val
                 230                 235                 240

 Asn Asn Met Ala His Asp Thr Asp Pro Lys Ala Leu Arg Leu Thr
                 245                 250                 255

 Asp Ser Ser Pro Ser Ser Thr Ser Thr Ser Asn Ser Gln Arg Leu
                 260                 265                 270

 Asp Ile Leu Lys Arg Arg Gln His Asp Val Lys Leu Glu Lys Leu
                 275                 280                 285

 Lys Glu Arg Ile Arg Lys Gln Trp Glu His Ser Glu Glu Thr Asn
                 290                 295                 300

 Gly Arg Gly Gln Lys Leu Gly His Ile Asp His Pro Val Met Val
                 305                 310                 315

 Val Asn Val Asp Asn Ser Val Thr Ala Lys Val Arg Lys Val Ala
                 320                 325                 330

 Thr Ala Pro Pro Ala Pro Ala Tyr Lys Gly Phe Asn Pro Ser Glu
                 335                 340                 345

 Thr Lys Ile Arg Thr Pro Asp Gly Lys Val Trp Gln Glu Ala Glu
                 350                 355                 360

 Phe Gln Asn Met Ser Arg Glu Leu Tyr Arg Asp Leu Ala Leu His
                 365                 370                 375

 Phe Ala Asp Asp Ile Ser Ile Lys Glu Lys Pro Ala Glu Lys Ser
                 380                 385                 390

 Lys Glu Lys Lys Val Val Lys Pro Val Arg Lys Val Gln Lys Val
                 395                 400                 405

 Ala Gln Leu Ser Ser Thr Glu Cys Arg Thr Gly Ser Ser His Leu
                 410                 415                 420

 Ile Ser Thr Ser Ser Trp Arg Asp Gly Gln Lys Leu Val Lys Lys
                 425                 430                 435

 Ile Leu Gly Pro Ala Pro Arg Met Glu Pro Lys Glu Gln Arg Thr
                 440                 445                 450

 Ala Ser Ser Asp Arg Gly Gly Arg Arg Arg Thr Ala Lys Ser Gly
                 455                 460                 465

 Gly His Ile Gly Arg Ala Glu Ser Asp Pro Arg Leu Asp Val Leu
                 470                 475                 480

 His Arg His Leu Gln Arg Asn Ser Glu Arg Ser Arg Ser Lys Ser
                 485                 490                 495

 Arg Ser Glu Asn Asn Ile Lys Lys Leu Ala Ser Ser Leu Pro Asp
                 500                 505                 510

 Asn Lys Gln Glu Glu Asn Thr Ala Leu Asn Lys Asp Phe Leu Pro
                 515                 520                 525

 Ile Glu Ile Arg Gly Ile Leu Asp Asp Leu Gln Leu Asp Ser Thr
                 530                 535                 540

 Ala His Thr Ala Lys Gln Asp Thr Val Glu Leu Gln Asn Gln Lys
                 545                 550                 555

 Ser Ser Ala Pro Val His Ala Pro Arg Ser His Ser Pro Val Lys
                 560                 565                 570

 Arg Lys Pro Asp Lys Ile Thr Ala Asn Glu Asp Pro Pro Val Ile
                 575                 580                 585

 Ser Lys Arg Arg His Tyr Asp Thr Asp Glu Val Arg Gln Tyr Ile
                 590                 595                 600

 Val Arg Gln Gln Glu Glu Arg Lys Arg Lys Gln Asn Glu Glu Lys
                 605                 610                 615

 Lys Ala Gln Lys Glu Ala Thr Glu Gln Lys Asn Lys Arg Leu Gln
                 620                 625                 630

 Glu Leu Tyr Arg Lys Gln Lys Glu Ala Phe Thr Lys Val Lys Asn
                 635                 640                 645

 Val Pro Pro Ser Glu Pro Ser Ala Thr Arg Arg Leu Gln Glu Thr
                 650                 655                 660

 Tyr Ser Lys Leu Leu Leu Glu Lys Thr Leu Leu Glu Glu Pro Ser
                 665                 670                 675

 His Gln His Val Thr Gln Glu Thr Gln Ala Lys Pro Gly Tyr Gln
                 680                 685                 690

 Pro Ser Gly Glu Ser Asp Lys Glu Asn Lys Val Gln Glu Arg Pro
                 695                 700                 705

 Pro Ser Ala Ser Ser Ser Ser Asp Met Ser Leu Ser Glu Pro Pro
                 710                 715                 720

 Gln Pro Leu Ala Arg Lys Asp Leu Met Glu Ser Thr Trp Met Gln
                 725                 730                 735

 Pro Glu Arg Leu Ser Pro Gln Val His His Ser Gln Pro Gln Pro
                 740                 745                 750

 Phe Ala Gly Thr Ala Gly Ser Leu Leu Ser His Leu Leu Ser Leu
                 755                 760                 765

 Glu His Val Gly Ile Leu His Lys Asp Phe Glu Ser Ile Leu Pro
                 770                 775                 780

 Thr Arg Lys Asn His Asn Met Ala Ser Arg Pro Leu Thr Phe Thr
                 785                 790                 795

 Pro Gln Pro Tyr Val Thr Ser Pro Ala Ala Tyr Thr Asp Ala Leu
                 800                 805                 810

 Leu Lys Pro Ser Ala Ser Gln Tyr Lys Ser Lys Leu Asp Arg Ile
                 815                 820                 825

 Glu Ala Leu Lys Ala Thr Ala Ala Ser Leu Ser Ser Arg Ile Glu
                 830                 835                 840

 Ser Glu Ala Lys Lys Leu Ala Gly Ala Ser Ile Asn Tyr Gly Ser
                 845                 850                 855

 Ala Trp Asn Thr Glu Tyr Asp Val Gln Gln Ala Pro Gln Glu Asp
                 860                 865                 870

 Gly Pro Trp Thr Lys Ala Val Thr Pro Pro Val Lys Asp Asp Asn
                 875                 880                 885

 Glu Asp Val Phe Ser Ala Arg Ile Gln Lys Met Leu Gly Ser Cys
                 890                 895                 900

 Val Ser His Ala Thr Phe Asp Asp Asp Leu Pro Gly Val Gly Asn
                 905                 910                 915

 Leu Ser Glu Phe Lys Lys Leu Pro Glu Met Ile Arg Pro Gln Ser
                 920                 925                 930

 Ala Ile Ser Ser Phe Arg Val Arg Ser Pro Gly Pro Lys Pro Gln
                 935                 940                 945

 Gly Leu Leu Ala Gln Leu Cys Lys Arg Gln Thr Asp Ser Ser Ser
                 950                 955                 960

 Ser Asp Met Gln Ala Cys Ser Gln Asp Lys Ala Lys Ile Ser Leu
                 965                 970                 975

 Gly Ser Ser Ile Asp Ser Val Ser Glu Gly Pro Leu Leu Ser Glu
                 980                 985                 990

 Gly Ser Leu Ser Glu Glu Glu Gly Asp Gln Asp Gly Gln Pro Leu
                 995                1000                1005

 Leu Lys Val Ala Glu Ile Leu Lys Glu Lys Glu Phe Cys Pro Gly
                1010                1015                1020

 Glu Arg Asn Ser Tyr Glu Pro Ile Lys Glu Phe Gln Lys Glu Ala
                1025                1030                1035

 Glu Lys Phe Leu Pro Leu Phe Gly His Ile Gly Gly Thr Gln Ser
                1040                1045                1050

 Lys Gly Pro Trp Glu Glu Leu Ala Lys Gly Ser Pro His Ser Val
                1055                1060                1065

 Ile Asn Ile Phe Thr Lys Ser Tyr Gln Leu Tyr Gly Lys Gly Phe
                1070                1075                1080

 Glu Asp Lys Leu Asp Arg Gly Thr Ser Thr Ser Arg Pro Leu Asn
                1085                1090                1095

 Ala Thr Ala Thr Pro Leu Ser Gly Val Ser Tyr Glu Asp Asp Phe
                1100                1105                1110

 Val Ser Ser Pro Gly Thr Gly Thr Ser Thr Glu Lys Lys Ser Thr
                1115                1120                1125

 Leu Glu Pro His Ser Thr Leu Ser Pro Gln Glu Asp His Ser Asn
                1130                1135                1140

 Arg Lys Ser Ala Tyr Asp Pro Ser Ser Val Asp Val Thr Ser Gln
                1145                1150                1155

 His Ser Ser Gly Ala Gln Ser Ala Ala Ser Ser Arg Ser Ser Thr
                1160                1165                1170

 Ser Ser Lys Gly Lys Lys Gly Lys Lys Glu Lys Thr Glu Trp Leu
                1175                1180                1185

 Asp Ser Phe Thr Gly Asn Val Gln Asn Ser Leu Leu Asp Glu Glu
                1190                1195                1200

 Lys Ala Glu Arg Gly Ser His Gln Gly Lys Lys Ser Gly Thr Ser
                1205                1210                1215

 Ser Lys Leu Ser Val Lys Asp Phe Glu Gln Thr Leu Asp Thr Asp
                1220                1225                1230

 Ser Thr Leu Glu Asp Leu Ser Gly His Ser Val Ser Val Ser Ser
                1235                1240                1245

 Asp Lys Gly Arg Ser Gln Lys Thr Pro Thr Ser Pro Leu Ser Pro
                1250                1255                1260

 Ser Ser Gln Lys Ser Leu Gln Phe Asp Val Ala Gly Thr Ser Ser
                1265                1270                1275

 Glu Arg Ser Lys Ser Ser Val Met Pro Pro Thr Ile Thr Gly Phe
                1280                1285                1290

 Lys Pro Asn Ala Pro Leu Thr Asp Leu Asn Pro Ala Ala Ser Arg
                1295                1300                1305

 Thr Thr Thr Glu Asn Met Ala Pro Ile Pro Gly Ser Lys Arg Phe
                1310                1315                1320

 Ser Pro Ala Gly Leu His His Arg Met Ala Ala Glu Leu Ser Tyr
                1325                1330                1335

 Leu Asn Ala Ile Glu Glu Ser Val Arg Gln Leu Ser Asp Val Glu
                1340                1345                1350

 Arg Val Arg Gly Ile Ser Leu Ala Gln Gln Glu Ser Val Ser Leu
                1355                1360                1365

 Ala Gln Ile Ile Lys Ala Gln Gln Gln Arg His Glu Arg Asp Leu
                1370                1375                1380

 Ala Leu Leu Lys Leu Lys Ala Glu Gln Glu Ala Leu Glu Ser Gln
                1385                1390                1395

 Arg Gln Leu Glu Glu Thr Arg Asn Lys Ala Ala Gln Val His Ala
                1400                1405                1410

 Glu Ser Leu Gln Gln Val Val Gln Ser Gln Arg Glu Val Thr Glu
                1415                1420                1425

 Val Leu Gln Glu Ala Thr Cys Lys Ile Ala Ala Gln Gln Ser Glu
                1430                1435                1440

 Thr Ala Arg Leu Thr Thr Asp Ala Ala Arg Gln Ile Cys Glu Met
                1445                1450                1455

 Ala Glu Leu Thr Arg Thr His Ile Ser Asp Ala Val Val Ala Ser
                1460                1465                1470

 Gly Ala Pro Leu Ala Ile Leu Tyr Asp His Gln Arg Gln His Leu
                1475                1480                1485

 Pro Asp Phe Val Lys Gln Leu Arg Thr Arg Thr Glu Thr Asp Arg
                1490                1495                1500

 Lys Ser Pro Ser Val Ser Leu Ser Gln Ser Lys Glu Gly Thr Leu
                1505                1510                1515

 Asp Ser Lys His Gln Lys Tyr Ser Ala Ser Tyr Asp Ser Tyr Ser
                1520                1525                1530

 Glu Ser Ser Gly Tyr Lys Asn His Asp Arg Arg Ser Ser Ser Gly
                1535                1540                1545

 Ser Ser Arg Gln Glu Ser Pro Ser Val Pro Ser Cys Lys Glu Asn
                1550                1555                1560

 Glu Lys Lys Leu Asn Gly Glu Lys Ile Glu Ser Ser Ile Asp Glu
                1565                1570                1575

 Gln Val Gln Thr Ala Ala Asp Asp Ser Leu Arg Ser Asp Ser Val
                1580                1585                1590

 Pro Ser Leu Pro Asp Glu Lys Asp Ser Thr Ser Ile Ala Thr Glu
                1595                1600                1605

 Tyr Ser Leu Lys Phe Asp Glu Ser Met Thr Glu Asp Glu Ile Glu
                1610                1615                1620

 Glu Gln Ser Phe Arg Ser Leu Leu Pro Ser Glu Ser His Arg Arg
                1625                1630                1635

 Phe Asn Met Glu Lys Arg Arg Gly His His Asp Asp Ser Asp Glu
                1640                1645                1650

 Glu Ala Ser Pro Glu Lys Thr Thr Leu Ser Thr Ala Lys Glu Leu
                1655                1660                1665

 Asn Met Pro Phe Ser Gly Gly Gln Asp Ser Phe Ser Lys Phe Thr
                1670                1675                1680

 Met Glu Met Val Arg Gln Tyr Met Lys Glu Glu Glu Met Arg Ala
                1685                1690                1695

 Ala His Gln Ser Ser Leu Leu Arg Leu Arg Glu Lys Ala Leu Lys
                1700                1705                1710

 Glu Lys Thr Lys Ala Glu Leu Ala Trp Leu Glu His Gln Lys Lys
                1715                1720                1725

 His Leu Arg Asp Lys Gly Glu Asp Asp Lys Met Pro Pro Leu Arg
                1730                1735                1740

 Lys Lys Gln Arg Gly Leu Leu Leu Arg Leu Gln Gln Glu Lys Ala
                1745                1750                1755

 Glu Ile Lys Arg Leu Gln Glu Ala Asn Lys Ala Ala Arg Lys Glu
                1760                1765                1770

 Arg Gln Leu Ile Leu Lys Gln Gln Glu Glu Ile Glu Lys Ile Arg
                1775                1780                1785

 Gln Thr Thr Ile Lys Leu Gln Glu Lys Leu Lys Ser Ala Gly Glu
                1790                1795                1800

 Ser Lys Leu Asp Ser His Ser Asp Asp Asp Thr Lys Asp Asn Lys
                1805                1810                1815

 Ala Thr Ser Pro Gly Pro Thr Asp Leu Glu Thr Arg Ser Pro Ser
                1820                1825                1830

 Pro Ile Ser Ile Ser Ser Ser Glu Thr Ser Ser Ile Met Gln Lys
                1835                1840                1845

 Leu Lys Lys Met Arg Ser Arg Met Asp Glu Lys Phe Leu Thr Lys
                1850                1855                1860

 Arg Glu Gln Lys Leu Met Gln Arg Arg Gln His Ala Glu Glu Leu
                1865                1870                1875

 Leu Glu Trp Lys Arg Arg Leu Asp Ala Glu Glu Ala Glu Ile Arg
                1880                1885                1890

 Gln Met Glu Lys Gln Ala Leu Ala Ala Trp Asp Lys Glu Leu Ile
                1895                1900                1905

 Lys Pro Lys Thr Pro Lys Lys Glu Leu Glu Asp Gln Arg Thr Glu
                1910                1915                1920

 Gln Lys Glu Ile Ala Ser Glu Glu Glu Ser Pro Val Pro Leu Tyr
                1925                1930                1935

 Ser His Leu Asn Ser Glu Ser Ser Ile Pro Glu Glu Leu Gly Ser
                1940                1945                1950

 Pro Ala Val Glu Tyr Val Pro Ser Glu Ser Ile Gly Gln Glu Gln
                1955                1960                1965

 Pro Gly Ser Pro Asp His Ser Ile Leu Thr Glu Glu Met Ile Cys
                1970                1975                1980

 Ser Gln Glu Leu Glu Ser Ser Thr Ser Pro Ser Lys His Ser Leu
                1985                1990                1995

 Pro Lys Ser Cys Thr
                2000

<210> 1121
<211> 3576
<212> DNA
<213> Homo sapien

<400> 1121
 ggatcgcgct gatgtggccc caaccccgcc tccctccccg ccccgcgatg 50

 tcggaagaaa cccgacagag caaattggcc gcagcgaaga aaaagttgag 100

 agaatatcag cagaggaata gccctggtgt tcctacagga gcgaaaaaga 150

 agaagaaaat aaaaaatggc agtaaccctg agacaaccac ttctggtggt 200

 tgccactcac ctgaggatac acccaaggac aatgctgcta ctctacaacc 250

 atctgatgac accgtgttac ctggcggtgt cccttcccct ggtgccagtc 300

 tcactagcat ggcggcatct cagaatcatg atgctgacaa tgtccctaat 350

 ctcatggatg aaaccaagac tttctcatca accgagagcc tgcgacaact 400

 ctcccaacag ctcaatggtc ttgtttgtga gtctgcgaca tgtgtcaatg 450

 gggagggccc tgcatcgtct gctaacctga aggatctgga gagccggtac 500

 caacagctag cggtagccct ggactccagc tatgtaacaa acaaacaact 550

 caatatcacg atagagaaat tgaaacaaca gaaccaagaa attacggatc 600

 agttggaaga agaaaagaaa gaatgccacc aaaagcaggg agccctaagg 650

 gagcagttac aggttcacat tcagaccata gggatcctcg tatcagagaa 700

 agctgagtta cagacagccc tggctcacac tcagcatgct gccaggcaga 750

 aagaaggaga gtctgaagat ctggccagcc gcctgcagta ttcccggcgg 800

 cgtgtgggag agttggagcg ggctctctct gctgtctcca cgcagcagaa 850

 gaaggcagac aggtacaaca aggagttaac caaagagaga gacgccctca 900

 ggctggagtt atacaagaac acccaaagca atgaggacct gaagcaagag 950

 aaatcagaat tggaagagaa gcttcgggtc ctagtgactg agaaggctgg 1000

 catgcagctt aacttggaag aattgcaaaa gaagttagag atgacggaac 1050

 tcctgcttca acagttttca agccggtgtg aagcccctga tgctaaccag 1100

 cagttacagc aggccatgga ggagcgggca cagctggaag cacacctggg 1150

 gcaggtaatg gagtcggtta gacaactaca aatggagaga gataaatatg 1200

 cggagaatct caaaggagag agcgccatgt ggcggcagag gatgcagcag 1250

 atgtcagagc aggtgcacac attgagagag gagaaggaat gtagcatgag 1300

 tcgggtacag gagctggaga cgagcttggc tgaactgagg aaccagatgg 1350

 ctgaaccccc gcccccagag cccccagcag ggccctccga ggtggagcag 1400

 cagctacaag cggaggctga gcacctgcgg aaggagctgg agggtctggc 1450

 aggacagctt caagcccagg tgcaagacaa tgagggcttg agtcgcctga 1500

 accgggagca ggaggagagg ctgctggagc tggagcgggc ggccgagctc 1550

 tggggggagc aggcggaggc gcgcaggcaa atcctggaga ccatgcagaa 1600

 cgaccgcact accatcagcc gcgcactctc ccagaaccgg gagctcaagg 1650

 agcagctggc tgagctgcag agcggatttg taaagctgac taatgagaac 1700

 atggagatca ccagcgcact gcagtcggag cagcacgtca agagggagct 1750

 gggaaagaag ctgggcgagc tgcaggagaa gctgagcgag ctgaaggaaa 1800

 cggtggagct gaagagccaa gaggctcaaa gtctgcagca gcagcgagac 1850

 cagtacctgg gacacctgca gcagtatgtg gccgcctatc agcagctgac 1900

 ctctgagaag gaggtgctgc ataatcagct actgctgcag acccagctcg 1950

 tggaccagct gcagcagcag gaagctcagg gcaaagcggt ggccgagatg 2000

 gcccgccaag agttgcagga aacccaggag cgcctggaag ctgccaccca 2050

 gcagaatcag cagctacggg cccagttgag cctcatggct caccctgggg 2100

 aaggagatgg actggaccgg gaggaggagg aggatgagga ggaggaggag 2150

 gaggaggcgg tggcagtacc tcagcccatg ccaagcatcc cggaggacct 2200

 ggagagccgg gaagccatgg tggcattttt caactcagct gtagccagtg 2250

 ccgaggagga gcaggcaagg ctacgtgggc agctgaagga gcaaagggtg 2300

 cgctgccggc gcctggctca cctgctggcc tcggcccaga aggagcctga 2350

 ggcagcagcc ccagccccag ggaccggggg tgattctgtg tgtggggaga 2400

 cccaccgggc cctgcagggg gccatggaga agctgcagag ccgctttatg 2450

 gagctcatgc aggagaaggc agacctgaag gagagggtag aggaactgga 2500

 acatcgctgc atccagcttt ctggagagac agacaccatt ggagagtaca 2550

 ttgcactgta ccagagccag agggcagtgc tgaaggagcg gcaccgggag 2600

 aaggaggagt acatcagcag gctggcccaa gacaaggagg agatgaaggt 2650

 gaagctgctg gagctgcagg agctggtctt acggcttgtg ggcgaccgca 2700

 acgagtggca tggcagattc ctggcagctg cccagaaccc tgctgatgag 2750

 cccacttcag gggccccagc cccccaggaa cttggggctg ccaaccagca 2800

 gggtgatctt tgcgaggtga gcctcgccgg cagtgtggag cctgcccaag 2850

 gagaggccag ggagggttct ccccgtgaca accccactgc acagcagatc 2900

 atgcagctgc ttcgtgagat gcagaacccc cgggagcgcc caggcttggg 2950

 cagcaacccc tgcattcctt ttttttaccg ggctgacgag aatgatgagg 3000

 tgaagatcac tgtcatctaa aagccggcta ctgtcagcaa agcctgaaga 3050

 agtggggctg gataccctgc ccccaccata tccctaccat cccttctcag 3100

 tcaacccttt acccttacag tagcaagcat agacccctgt ctaacggggg 3150

 tagacaggtg cagatgaggt gaagatcact gtcatctaaa agctggccac 3200

 taaattaaaa aaaaattaaa agttatggga ttaaaaaaag ttatgggata 3250

 aaaaaggtta tgggtaactt atggtataaa agttatgaaa aaaggccagg 3300

 tgcagtggct cacgcctgta atcccagcac ttttgggagg ctgaggttgg 3350

 gagttcaaga ccagcctggt caacatggtg aaactgtgtc tctactaaaa 3400

 atacaaaaat tagccaggca tggtggcacg tgcctgtaat cccagctact 3450

 cgggaggctg aggcaggaga atcgcttgaa cctgggaggt ggaggttgca 3500

 gtgggctgag atcacgccat tgcactccag cctgggcgac agagtgagac 3550

 tctgtctcaa aaaaaaaaaa aaaaaa 3576

<210> 1122
<211> 990
<212> PRT
<213> Homo sapien

<400> 1122
 Met Ser Glu Glu Thr Arg Gln Ser Lys Leu Ala Ala Ala Lys Lys
   1               5                  10                  15

 Lys Leu Arg Glu Tyr Gln Gln Arg Asn Ser Pro Gly Val Pro Thr
                  20                  25                  30

 Gly Ala Lys Lys Lys Lys Lys Ile Lys Asn Gly Ser Asn Pro Glu
                  35                  40                  45

 Thr Thr Thr Ser Gly Gly Cys His Ser Pro Glu Asp Thr Pro Lys
                  50                  55                  60

 Asp Asn Ala Ala Thr Leu Gln Pro Ser Asp Asp Thr Val Leu Pro
                  65                  70                  75

 Gly Gly Val Pro Ser Pro Gly Ala Ser Leu Thr Ser Met Ala Ala
                  80                  85                  90

 Ser Gln Asn His Asp Ala Asp Asn Val Pro Asn Leu Met Asp Glu
                  95                 100                 105

 Thr Lys Thr Phe Ser Ser Thr Glu Ser Leu Arg Gln Leu Ser Gln
                 110                 115                 120

 Gln Leu Asn Gly Leu Val Cys Glu Ser Ala Thr Cys Val Asn Gly
                 125                 130                 135

 Glu Gly Pro Ala Ser Ser Ala Asn Leu Lys Asp Leu Glu Ser Arg
                 140                 145                 150

 Tyr Gln Gln Leu Ala Val Ala Leu Asp Ser Ser Tyr Val Thr Asn
                 155                 160                 165

 Lys Gln Leu Asn Ile Thr Ile Glu Lys Leu Lys Gln Gln Asn Gln
                 170                 175                 180

 Glu Ile Thr Asp Gln Leu Glu Glu Glu Lys Lys Glu Cys His Gln
                 185                 190                 195

 Lys Gln Gly Ala Leu Arg Glu Gln Leu Gln Val His Ile Gln Thr
                 200                 205                 210

 Ile Gly Ile Leu Val Ser Glu Lys Ala Glu Leu Gln Thr Ala Leu
                 215                 220                 225

 Ala His Thr Gln His Ala Ala Arg Gln Lys Glu Gly Glu Ser Glu
                 230                 235                 240

 Asp Leu Ala Ser Arg Leu Gln Tyr Ser Arg Arg Arg Val Gly Glu
                 245                 250                 255

 Leu Glu Arg Ala Leu Ser Ala Val Ser Thr Gln Gln Lys Lys Ala
                 260                 265                 270

 Asp Arg Tyr Asn Lys Glu Leu Thr Lys Glu Arg Asp Ala Leu Arg
                 275                 280                 285

 Leu Glu Leu Tyr Lys Asn Thr Gln Ser Asn Glu Asp Leu Lys Gln
                 290                 295                 300

 Glu Lys Ser Glu Leu Glu Glu Lys Leu Arg Val Leu Val Thr Glu
                 305                 310                 315

 Lys Ala Gly Met Gln Leu Asn Leu Glu Glu Leu Gln Lys Lys Leu
                 320                 325                 330

 Glu Met Thr Glu Leu Leu Leu Gln Gln Phe Ser Ser Arg Cys Glu
                 335                 340                 345

 Ala Pro Asp Ala Asn Gln Gln Leu Gln Gln Ala Met Glu Glu Arg
                 350                 355                 360

 Ala Gln Leu Glu Ala His Leu Gly Gln Val Met Glu Ser Val Arg
                 365                 370                 375

 Gln Leu Gln Met Glu Arg Asp Lys Tyr Ala Glu Asn Leu Lys Gly
                 380                 385                 390

 Glu Ser Ala Met Trp Arg Gln Arg Met Gln Gln Met Ser Glu Gln
                 395                 400                 405

 Val His Thr Leu Arg Glu Glu Lys Glu Cys Ser Met Ser Arg Val
                 410                 415                 420

 Gln Glu Leu Glu Thr Ser Leu Ala Glu Leu Arg Asn Gln Met Ala
                 425                 430                 435

 Glu Pro Pro Pro Pro Glu Pro Pro Ala Gly Pro Ser Glu Val Glu
                 440                 445                 450

 Gln Gln Leu Gln Ala Glu Ala Glu His Leu Arg Lys Glu Leu Glu
                 455                 460                 465

 Gly Leu Ala Gly Gln Leu Gln Ala Gln Val Gln Asp Asn Glu Gly
                 470                 475                 480

 Leu Ser Arg Leu Asn Arg Glu Gln Glu Glu Arg Leu Leu Glu Leu
                 485                 490                 495

 Glu Arg Ala Ala Glu Leu Trp Gly Glu Gln Ala Glu Ala Arg Arg
                 500                 505                 510

 Gln Ile Leu Glu Thr Met Gln Asn Asp Arg Thr Thr Ile Ser Arg
                 515                 520                 525

 Ala Leu Ser Gln Asn Arg Glu Leu Lys Glu Gln Leu Ala Glu Leu
                 530                 535                 540

 Gln Ser Gly Phe Val Lys Leu Thr Asn Glu Asn Met Glu Ile Thr
                 545                 550                 555

 Ser Ala Leu Gln Ser Glu Gln His Val Lys Arg Glu Leu Gly Lys
                 560                 565                 570

 Lys Leu Gly Glu Leu Gln Glu Lys Leu Ser Glu Leu Lys Glu Thr
                 575                 580                 585

 Val Glu Leu Lys Ser Gln Glu Ala Gln Ser Leu Gln Gln Gln Arg
                 590                 595                 600

 Asp Gln Tyr Leu Gly His Leu Gln Gln Tyr Val Ala Ala Tyr Gln
                 605                 610                 615

 Gln Leu Thr Ser Glu Lys Glu Val Leu His Asn Gln Leu Leu Leu
                 620                 625                 630

 Gln Thr Gln Leu Val Asp Gln Leu Gln Gln Gln Glu Ala Gln Gly
                 635                 640                 645

 Lys Ala Val Ala Glu Met Ala Arg Gln Glu Leu Gln Glu Thr Gln
                 650                 655                 660

 Glu Arg Leu Glu Ala Ala Thr Gln Gln Asn Gln Gln Leu Arg Ala
                 665                 670                 675

 Gln Leu Ser Leu Met Ala His Pro Gly Glu Gly Asp Gly Leu Asp
                 680                 685                 690

 Arg Glu Glu Glu Glu Asp Glu Glu Glu Glu Glu Glu Glu Ala Val
                 695                 700                 705

 Ala Val Pro Gln Pro Met Pro Ser Ile Pro Glu Asp Leu Glu Ser
                 710                 715                 720

 Arg Glu Ala Met Val Ala Phe Phe Asn Ser Ala Val Ala Ser Ala
                 725                 730                 735

 Glu Glu Glu Gln Ala Arg Leu Arg Gly Gln Leu Lys Glu Gln Arg
                 740                 745                 750

 Val Arg Cys Arg Arg Leu Ala His Leu Leu Ala Ser Ala Gln Lys
                 755                 760                 765

 Glu Pro Glu Ala Ala Ala Pro Ala Pro Gly Thr Gly Gly Asp Ser
                 770                 775                 780

 Val Cys Gly Glu Thr His Arg Ala Leu Gln Gly Ala Met Glu Lys
                 785                 790                 795

 Leu Gln Ser Arg Phe Met Glu Leu Met Gln Glu Lys Ala Asp Leu
                 800                 805                 810

 Lys Glu Arg Val Glu Glu Leu Glu His Arg Cys Ile Gln Leu Ser
                 815                 820                 825

 Gly Glu Thr Asp Thr Ile Gly Glu Tyr Ile Ala Leu Tyr Gln Ser
                 830                 835                 840

 Gln Arg Ala Val Leu Lys Glu Arg His Arg Glu Lys Glu Glu Tyr
                 845                 850                 855

 Ile Ser Arg Leu Ala Gln Asp Lys Glu Glu Met Lys Val Lys Leu
                 860                 865                 870

 Leu Glu Leu Gln Glu Leu Val Leu Arg Leu Val Gly Asp Arg Asn
                 875                 880                 885

 Glu Trp His Gly Arg Phe Leu Ala Ala Ala Gln Asn Pro Ala Asp
                 890                 895                 900

 Glu Pro Thr Ser Gly Ala Pro Ala Pro Gln Glu Leu Gly Ala Ala
                 905                 910                 915

 Asn Gln Gln Gly Asp Leu Cys Glu Val Ser Leu Ala Gly Ser Val
                 920                 925                 930

 Glu Pro Ala Gln Gly Glu Ala Arg Glu Gly Ser Pro Arg Asp Asn
                 935                 940                 945

 Pro Thr Ala Gln Gln Ile Met Gln Leu Leu Arg Glu Met Gln Asn
                 950                 955                 960

 Pro Arg Glu Arg Pro Gly Leu Gly Ser Asn Pro Cys Ile Pro Phe
                 965                 970                 975

 Phe Tyr Arg Ala Asp Glu Asn Asp Glu Val Lys Ile Thr Val Ile
                 980                 985                 990

<210> 1123
<211> 1925
<212> DNA
<213> Homo sapien

<400> 1123
 ctgacacgct cctgggtcgt aggcacagga gtgggggcca aagcatggag 50

 aatcaagaga aggcgagtat cgcgggccac atgttcgacg tagtcgtgat 100

 cggaggtggc atttcaggac tatctgctgc caaactcttg actgaatatg 150

 gcgttagtgt tttggtttta gaagctcggg acagggttgg aggaagaaca 200

 tatactataa ggaatgagca tgttgattac gtagatgttg gtggagctta 250

 tgtgggacca acccaaaaca gaatcttacg cttgtctaag gagctgggca 300

 tagagactta caaagtgaat gtcagtgagc gtctcgttca atatgtcaag 350

 gggaaaacat atccatttcg gggcgccttt ccaccagtat ggaatcccat 400

 tgcatatttg gattacaata atctgtggag gacaatagat aacatgggga 450

 aggagattcc aactgatgca ccctgggagg ctcaacatgc tgacaaatgg 500

 gacaaaatga ccatgaaaga gctcattgac aaaatctgct ggacaaagac 550

 tgctaggcgg tttgcttatc tttttgtgaa tatcaatgtg acctctgagc 600

 ctcacgaagt gtctgccctg tggttcttgt ggtatgtgaa gcagtgcggg 650

 ggcaccactc ggatattctc tgtcaccaat ggtggccagg aacggaagtt 700

 tgtaggtgga tctggtcaag tgagcgaacg gataatggac ctcctcggag 750

 accaagtgaa gctgaaccat cctgtcactc acgttgacca gtcaagtgac 800

 aacatcatca tagagacgct gaaccatgaa cattatgagt gcaaatacgt 850

 aattaatgcg atccctccga ccttgactgc caagattcac ttcagaccag 900

 agcttccagc agagagaaac cagttaattc agcgtcttcc aatgggagct 950

 gtcattaagt gcatgatgta ttacaaggag gccttctgga agaagaagga 1000

 ttactgtggc tgcatgatca ttgaagatga agatgctcca atttcaataa 1050

 ccttggatga caccaagcca gatgggtcac tgcctgccat catgggcttc 1100

 attcttgccc ggaaagctga tcgacttgct aagctacata aggaaataag 1150

 gaagaagaaa atctgtgagc tctatgccaa agtgctggga tcccaagaag 1200

 ctttacatcc agtgcattat gaagagaaga actggtgtga ggagcagtac 1250

 tctgggggct gctacacggc ctacttccct cctgggatca tgactcaata 1300

 tggaagggtg attcgtcaac ccgtgggcag gattttcttt gcgggcacag 1350

 agactgccac aaagtggagc ggctacatgg aaggggcagt tgaggctgga 1400

 gaacgagcag ctagggaggt cttaaatggt ctcgggaagg tgaccgagaa 1450

 agacatctgg gtacaagaac ctgaatcaaa ggacgttcca gcggtagaaa 1500

 tcacccacac cttctgggaa aggaacctgc cctctgtttc tggcctgctg 1550

 aagatcattg gattttccac atcagtaact gccctggggt ttgtgctgta 1600

 caaatacaag ctcctgccac ggtcttgaag ttctgttctt atgctctctg 1650

 ctcactggtt ttcaatacca ccaagaggaa aatattgaca agtttaaagg 1700

 ctgtgtcatt gggccatgtt taagtgtact ggatttaact acctttggct 1750

 taattccaat cattgttaaa gtaaaaacaa ttcaaagaat cacctaatta 1800

 atttcagtaa gatcaagctc catcttattt gtcagtgtag atcaactcat 1850

 gttaattgat agaataaagc cttgtgatca ctttctgaaa ttcacaaagt 1900

 taaacgtgat gtgctcatca gaaac 1925

<210> 1124
<211> 527
<212> PRT
<213> Homo sapien

<400> 1124
 Met Glu Asn Gln Glu Lys Ala Ser Ile Ala Gly His Met Phe Asp
   1               5                  10                  15

 Val Val Val Ile Gly Gly Gly Ile Ser Gly Leu Ser Ala Ala Lys
                  20                  25                  30

 Leu Leu Thr Glu Tyr Gly Val Ser Val Leu Val Leu Glu Ala Arg
                  35                  40                  45

 Asp Arg Val Gly Gly Arg Thr Tyr Thr Ile Arg Asn Glu His Val
                  50                  55                  60

 Asp Tyr Val Asp Val Gly Gly Ala Tyr Val Gly Pro Thr Gln Asn
                  65                  70                  75

 Arg Ile Leu Arg Leu Ser Lys Glu Leu Gly Ile Glu Thr Tyr Lys
                  80                  85                  90

 Val Asn Val Ser Glu Arg Leu Val Gln Tyr Val Lys Gly Lys Thr
                  95                 100                 105

 Tyr Pro Phe Arg Gly Ala Phe Pro Pro Val Trp Asn Pro Ile Ala
                 110                 115                 120

 Tyr Leu Asp Tyr Asn Asn Leu Trp Arg Thr Ile Asp Asn Met Gly
                 125                 130                 135

 Lys Glu Ile Pro Thr Asp Ala Pro Trp Glu Ala Gln His Ala Asp
                 140                 145                 150

 Lys Trp Asp Lys Met Thr Met Lys Glu Leu Ile Asp Lys Ile Cys
                 155                 160                 165

 Trp Thr Lys Thr Ala Arg Arg Phe Ala Tyr Leu Phe Val Asn Ile
                 170                 175                 180

 Asn Val Thr Ser Glu Pro His Glu Val Ser Ala Leu Trp Phe Leu
                 185                 190                 195

 Trp Tyr Val Lys Gln Cys Gly Gly Thr Thr Arg Ile Phe Ser Val
                 200                 205                 210

 Thr Asn Gly Gly Gln Glu Arg Lys Phe Val Gly Gly Ser Gly Gln
                 215                 220                 225

 Val Ser Glu Arg Ile Met Asp Leu Leu Gly Asp Gln Val Lys Leu
                 230                 235                 240

 Asn His Pro Val Thr His Val Asp Gln Ser Ser Asp Asn Ile Ile
                 245                 250                 255

 Ile Glu Thr Leu Asn His Glu His Tyr Glu Cys Lys Tyr Val Ile
                 260                 265                 270

 Asn Ala Ile Pro Pro Thr Leu Thr Ala Lys Ile His Phe Arg Pro
                 275                 280                 285

 Glu Leu Pro Ala Glu Arg Asn Gln Leu Ile Gln Arg Leu Pro Met
                 290                 295                 300

 Gly Ala Val Ile Lys Cys Met Met Tyr Tyr Lys Glu Ala Phe Trp
                 305                 310                 315

 Lys Lys Lys Asp Tyr Cys Gly Cys Met Ile Ile Glu Asp Glu Asp
                 320                 325                 330

 Ala Pro Ile Ser Ile Thr Leu Asp Asp Thr Lys Pro Asp Gly Ser
                 335                 340                 345

 Leu Pro Ala Ile Met Gly Phe Ile Leu Ala Arg Lys Ala Asp Arg
                 350                 355                 360

 Leu Ala Lys Leu His Lys Glu Ile Arg Lys Lys Lys Ile Cys Glu
                 365                 370                 375

 Leu Tyr Ala Lys Val Leu Gly Ser Gln Glu Ala Leu His Pro Val
                 380                 385                 390

 His Tyr Glu Glu Lys Asn Trp Cys Glu Glu Gln Tyr Ser Gly Gly
                 395                 400                 405

 Cys Tyr Thr Ala Tyr Phe Pro Pro Gly Ile Met Thr Gln Tyr Gly
                 410                 415                 420

 Arg Val Ile Arg Gln Pro Val Gly Arg Ile Phe Phe Ala Gly Thr
                 425                 430                 435

 Glu Thr Ala Thr Lys Trp Ser Gly Tyr Met Glu Gly Ala Val Glu
                 440                 445                 450

 Ala Gly Glu Arg Ala Ala Arg Glu Val Leu Asn Gly Leu Gly Lys
                 455                 460                 465

 Val Thr Glu Lys Asp Ile Trp Val Gln Glu Pro Glu Ser Lys Asp
                 470                 475                 480

 Val Pro Ala Val Glu Ile Thr His Thr Phe Trp Glu Arg Asn Leu
                 485                 490                 495

 Pro Ser Val Ser Gly Leu Leu Lys Ile Ile Gly Phe Ser Thr Ser
                 500                 505                 510

 Val Thr Ala Leu Gly Phe Val Leu Tyr Lys Tyr Lys Leu Leu Pro
                 515                 520                 525

 Arg Ser


<210> 1125
<211> 1925
<212> DNA
<213> Homo sapien

<400> 1125
 ctgacacgct cctgggtcgt aggcacagga gtgggggcca aagcatggag 50

 aatcaagaga aggcgagtat cgcgggccac atgttcgacg tagtcgtgat 100

 cggaggtggc atttcaggac tatctgctgc caaactcttg actgaatatg 150

 gcgttagtgt tttggtttta gaagctcggg acagggttgg aggaagaaca 200

 tatactataa ggaatgagca tgttgattac gtagatgttg gtggagctta 250

 tgtgggacca acccaaaaca gaatcttacg cttgtctaag gagctgggca 300

 tagagactta caaagtgaat gtcagtgagc gtctcgttca atatgtcaag 350

 gggaaaacat atccatttcg gggcgccttt ccaccagtat ggaatcccat 400

 tgcatatttg gattacaata atctgtggag gacaatagat aacatgggga 450

 aggagattcc aactgatgca ccctgggagg ctcaacatgc tgacaaatgg 500

 gacaaaatga ccatgaaaga gctcattgac aaaatctgct ggacaaagac 550

 tgctaggcgg tttgcttatc tttttgtgaa tatcaatgtg acctctgagc 600

 ctcacgaagt gtctgccctg tggttcttgt ggtatgtgaa gcagtgcggg 650

 ggcaccactc ggatattctc tgtcaccaat ggtggccagg aacggaagtt 700

 tgtaggtgga tctggtcaag tgagcgaacg gataatggac ctcctcggag 750

 accaagtgaa gctgaaccat cctgtcactc acgttgacca gtcaagtgac 800

 aacatcatca tagagacgct gaaccatgaa cattatgagt gcaaatacgt 850

 aattaatgcg atccctccga ccttgactgc caagattcac ttcagaccag 900

 agcttccagc agagagaaac cagttaattc agcgtcttcc aatgggagct 950

 gtcattaagt gcatgatgta ttacaaggag gccttctgga agaagaagga 1000

 ttactgtggc tgcatgatca ttgaagatga agatgctcca atttcaataa 1050

 ccttggatga caccaagcca gatgggtcac tgcctgccat catgggcttc 1100

 attcttgccc ggaaagctga tcgacttgct aagctacata aggaaataag 1150

 gaagaagaaa atctgtgagc tctatgccaa agtgctggga tcccaagaag 1200

 ctttacatcc agtgcattat gaagagaaga actggtgtga ggagcagtac 1250

 tctgggggct gctacacggc ctacttccct cctgggatca tgactcaata 1300

 tggaagggtg attcgtcaac ccgtgggcag gattttcttt gcgggcacag 1350

 agactgccac aaagtggagc ggctacatgg aaggggcagt tgaggctgga 1400

 gaacgagcag ctagggaggt cttaaatggt ctcgggaagg tgaccgagaa 1450

 agacatctgg gtacaagaac ctgaatcaaa ggacgttcca gcggtagaaa 1500

 tcacccacac cttctgggaa aggaacctgc cctctgtttc tggcctgctg 1550

 aagatcattg gattttccac atcagtaact gccctggggt ttgtgctgta 1600

 caaatacaag ctcctgccac ggtcttgaag ttctgttctt atgctctctg 1650

 ctcactggtt ttcaatacca ccaagaggaa aatattgaca agtttaaagg 1700

 ctgtgtcatt gggccatgtt taagtgtact ggatttaact acctttggct 1750

 taattccaat cattgttaaa gtaaaaacaa ttcaaagaat cacctaatta 1800

 atttcagtaa gatcaagctc catcttattt gtcagtgtag atcaactcat 1850

 gttaattgat agaataaagc cttgtgatca ctttctgaaa ttcacaaagt 1900

 taaacgtgat gtgctcatca gaaac 1925

<210> 1126
<211> 527
<212> PRT
<213> Homo sapien

<400> 1126
 Met Glu Asn Gln Glu Lys Ala Ser Ile Ala Gly His Met Phe Asp
   1               5                  10                  15

 Val Val Val Ile Gly Gly Gly Ile Ser Gly Leu Ser Ala Ala Lys
                  20                  25                  30

 Leu Leu Thr Glu Tyr Gly Val Ser Val Leu Val Leu Glu Ala Arg
                  35                  40                  45

 Asp Arg Val Gly Gly Arg Thr Tyr Thr Ile Arg Asn Glu His Val
                  50                  55                  60

 Asp Tyr Val Asp Val Gly Gly Ala Tyr Val Gly Pro Thr Gln Asn
                  65                  70                  75

 Arg Ile Leu Arg Leu Ser Lys Glu Leu Gly Ile Glu Thr Tyr Lys
                  80                  85                  90

 Val Asn Val Ser Glu Arg Leu Val Gln Tyr Val Lys Gly Lys Thr
                  95                 100                 105

 Tyr Pro Phe Arg Gly Ala Phe Pro Pro Val Trp Asn Pro Ile Ala
                 110                 115                 120

 Tyr Leu Asp Tyr Asn Asn Leu Trp Arg Thr Ile Asp Asn Met Gly
                 125                 130                 135

 Lys Glu Ile Pro Thr Asp Ala Pro Trp Glu Ala Gln His Ala Asp
                 140                 145                 150

 Lys Trp Asp Lys Met Thr Met Lys Glu Leu Ile Asp Lys Ile Cys
                 155                 160                 165

 Trp Thr Lys Thr Ala Arg Arg Phe Ala Tyr Leu Phe Val Asn Ile
                 170                 175                 180

 Asn Val Thr Ser Glu Pro His Glu Val Ser Ala Leu Trp Phe Leu
                 185                 190                 195

 Trp Tyr Val Lys Gln Cys Gly Gly Thr Thr Arg Ile Phe Ser Val
                 200                 205                 210

 Thr Asn Gly Gly Gln Glu Arg Lys Phe Val Gly Gly Ser Gly Gln
                 215                 220                 225

 Val Ser Glu Arg Ile Met Asp Leu Leu Gly Asp Gln Val Lys Leu
                 230                 235                 240

 Asn His Pro Val Thr His Val Asp Gln Ser Ser Asp Asn Ile Ile
                 245                 250                 255

 Ile Glu Thr Leu Asn His Glu His Tyr Glu Cys Lys Tyr Val Ile
                 260                 265                 270

 Asn Ala Ile Pro Pro Thr Leu Thr Ala Lys Ile His Phe Arg Pro
                 275                 280                 285

 Glu Leu Pro Ala Glu Arg Asn Gln Leu Ile Gln Arg Leu Pro Met
                 290                 295                 300

 Gly Ala Val Ile Lys Cys Met Met Tyr Tyr Lys Glu Ala Phe Trp
                 305                 310                 315

 Lys Lys Lys Asp Tyr Cys Gly Cys Met Ile Ile Glu Asp Glu Asp
                 320                 325                 330

 Ala Pro Ile Ser Ile Thr Leu Asp Asp Thr Lys Pro Asp Gly Ser
                 335                 340                 345

 Leu Pro Ala Ile Met Gly Phe Ile Leu Ala Arg Lys Ala Asp Arg
                 350                 355                 360

 Leu Ala Lys Leu His Lys Glu Ile Arg Lys Lys Lys Ile Cys Glu
                 365                 370                 375

 Leu Tyr Ala Lys Val Leu Gly Ser Gln Glu Ala Leu His Pro Val
                 380                 385                 390

 His Tyr Glu Glu Lys Asn Trp Cys Glu Glu Gln Tyr Ser Gly Gly
                 395                 400                 405

 Cys Tyr Thr Ala Tyr Phe Pro Pro Gly Ile Met Thr Gln Tyr Gly
                 410                 415                 420

 Arg Val Ile Arg Gln Pro Val Gly Arg Ile Phe Phe Ala Gly Thr
                 425                 430                 435

 Glu Thr Ala Thr Lys Trp Ser Gly Tyr Met Glu Gly Ala Val Glu
                 440                 445                 450

 Ala Gly Glu Arg Ala Ala Arg Glu Val Leu Asn Gly Leu Gly Lys
                 455                 460                 465

 Val Thr Glu Lys Asp Ile Trp Val Gln Glu Pro Glu Ser Lys Asp
                 470                 475                 480

 Val Pro Ala Val Glu Ile Thr His Thr Phe Trp Glu Arg Asn Leu
                 485                 490                 495

 Pro Ser Val Ser Gly Leu Leu Lys Ile Ile Gly Phe Ser Thr Ser
                 500                 505                 510

 Val Thr Ala Leu Gly Phe Val Leu Tyr Lys Tyr Lys Leu Leu Pro
                 515                 520                 525

 Arg Ser


<210> 1127
<211> 2240
<212> DNA
<213> Homo sapien

<400> 1127
 gtccttcggt gtctgggtgt ggtgagtaga ggtgtgtgtc acaaagtaca 50

 gaccattgtg tgtgacaaag cccatcgtgt gtctgtgtgt gtctttatcc 100

 acgtggatgg acgtctcttt cttgctctgc cccaagacac accctagccc 150

 ctccttattc tcaaaagggg gagctgggga gcctccccct accctggggc 200

 ctcccctgcc cctccccgcc ctgcctggcc gtcaccactc cccagagggc 250

 acagggctct gctgtgcctc agagcaaaag tcccagagcc agcagagcag 300

 gctgacgacc tgcaagccac agtggctgcc ctgtgcgtgc tgcgaggtgg 350

 gggaccctgg gcaggaagct ggctgagccc caagaccccg ggggccatgg 400

 gcggggatct ggtgcttggc ctgggggcct tgagacgccg aaagcgcttg 450

 ctggagcagg agaagtctct ggccggctgg gcactggtgc tggcaggaac 500

 tggcattgga ctcatggtgc tgcatgcaga gatgctgtgg ttcggggggt 550

 gctcgtgggc gctctacctg ttcctggtta aatgcacgat cagcatttcc 600

 accttcttac tcctctgcct catcgtggcc tttcatgcca aagaggtcca 650

 gctgttcatg accgacaacg ggctgcggga ctggcgcgtg gcgctgaccg 700

 ggcggcaggc ggcgcagatc gtgctggagc tggtggtgtg tgggctgcac 750

 ccggcgcccg tgcggggccc gccgtgcgtg caggatttag gggcgccgct 800

 gacctccccg cagccctggc cgggattcct gggccaaggg gaagcgctgc 850

 tgtccctggc catgctgctg cgtctctacc tggtgccccg cgccgtgctc 900

 ctgcgcagcg gcgtcctgct caacgcttcc taccgcagca tcggcgctct 950

 caatcaagtc cgcttccgcc actggttcgt ggccaagctt tacatgaaca 1000

 cgcaccctgg ccgcctgctg ctcggcctca cgcttggcct ctggctgacc 1050

 accgcctggg tgctgtccgt ggccgagagg caggctgtta atgccactgg 1100

 gcacctttca gacacacttt ggctgatccc catcacattc ctgaccatcg 1150

 gctatggtga cgtggtgccg ggcaccatgt ggggcaagat cgtctgcctg 1200

 tgcactggag tcatgggtgt ctgctgcaca gccctgctgg tggccgtggt 1250

 ggcccggaag ctggagttta acaaggcaga gaagcacgtg cacaacttca 1300

 tgatggatat ccagtatacc aaagagatga aggagtccgc tgcccgagtg 1350

 ctacaagaag cctggatgtt ctacaaacat actcgcagga aggagtctca 1400

 tgctgcccgc aggcatcagc gcaagctgct ggccgccatc aacgcgttcc 1450

 gccaggtgcg gctgaaacac cggaagctcc gggaacaagt gaactccatg 1500

 gtggacatct ccaagatgca catgatcctg tatgacctgc agcagaatct 1550

 gagcagctca caccgggccc tggagaaaca gattgacacg ctggcgggga 1600

 agctggatgc cctgactgag ctgcttagca ctgccctggg gccgaggcag 1650

 cttccagaac ccagccagca gtccaagtag ctggacccac gaggaggaac 1700

 caggctactt tccccagtac tgaggtggtg gacatcgtct ctgccactcc 1750

 tgacccagcc ctgaacaaag cacctcaagt gcaaggacca aagggggccc 1800

 tggcttggag tgggttggct tgctgatggc tgctggaggg gacgctggct 1850

 aaagtgggta ggccttggcc cacctgaggc cccaggtggg aacatggtca 1900

 cccccactct gcataccctc atcaaaaaca ctctcactat gctgctatgg 1950

 acgacctcca gctctcagtt acaagtgcag gcgactggag gcaggactcc 2000

 tgggtccctg ggaaagaggg tactaggggc ccggatccag gattctggga 2050

 ggcttcagtt accgctggcc gagctgaaga actgggtatg aggctggggc 2100

 ggggctggag gtggcgcccc ctggtgggac aacaaagagg acaccatttt 2150

 tccagagctg cagagagcac ctggtgggga ggaagaagtg taactcacca 2200

 gcctctgctc ttatctttgt aataaatgtt aaagccagaa 2240

<210> 1128
<211> 427
<212> PRT
<213> Homo sapien

<400> 1128
 Met Gly Gly Asp Leu Val Leu Gly Leu Gly Ala Leu Arg Arg Arg
   1               5                  10                  15

 Lys Arg Leu Leu Glu Gln Glu Lys Ser Leu Ala Gly Trp Ala Leu
                  20                  25                  30

 Val Leu Ala Gly Thr Gly Ile Gly Leu Met Val Leu His Ala Glu
                  35                  40                  45

 Met Leu Trp Phe Gly Gly Cys Ser Trp Ala Leu Tyr Leu Phe Leu
                  50                  55                  60

 Val Lys Cys Thr Ile Ser Ile Ser Thr Phe Leu Leu Leu Cys Leu
                  65                  70                  75

 Ile Val Ala Phe His Ala Lys Glu Val Gln Leu Phe Met Thr Asp
                  80                  85                  90

 Asn Gly Leu Arg Asp Trp Arg Val Ala Leu Thr Gly Arg Gln Ala
                  95                 100                 105

 Ala Gln Ile Val Leu Glu Leu Val Val Cys Gly Leu His Pro Ala
                 110                 115                 120

 Pro Val Arg Gly Pro Pro Cys Val Gln Asp Leu Gly Ala Pro Leu
                 125                 130                 135

 Thr Ser Pro Gln Pro Trp Pro Gly Phe Leu Gly Gln Gly Glu Ala
                 140                 145                 150

 Leu Leu Ser Leu Ala Met Leu Leu Arg Leu Tyr Leu Val Pro Arg
                 155                 160                 165

 Ala Val Leu Leu Arg Ser Gly Val Leu Leu Asn Ala Ser Tyr Arg
                 170                 175                 180

 Ser Ile Gly Ala Leu Asn Gln Val Arg Phe Arg His Trp Phe Val
                 185                 190                 195

 Ala Lys Leu Tyr Met Asn Thr His Pro Gly Arg Leu Leu Leu Gly
                 200                 205                 210

 Leu Thr Leu Gly Leu Trp Leu Thr Thr Ala Trp Val Leu Ser Val
                 215                 220                 225

 Ala Glu Arg Gln Ala Val Asn Ala Thr Gly His Leu Ser Asp Thr
                 230                 235                 240

 Leu Trp Leu Ile Pro Ile Thr Phe Leu Thr Ile Gly Tyr Gly Asp
                 245                 250                 255

 Val Val Pro Gly Thr Met Trp Gly Lys Ile Val Cys Leu Cys Thr
                 260                 265                 270

 Gly Val Met Gly Val Cys Cys Thr Ala Leu Leu Val Ala Val Val
                 275                 280                 285

 Ala Arg Lys Leu Glu Phe Asn Lys Ala Glu Lys His Val His Asn
                 290                 295                 300

 Phe Met Met Asp Ile Gln Tyr Thr Lys Glu Met Lys Glu Ser Ala
                 305                 310                 315

 Ala Arg Val Leu Gln Glu Ala Trp Met Phe Tyr Lys His Thr Arg
                 320                 325                 330

 Arg Lys Glu Ser His Ala Ala Arg Arg His Gln Arg Lys Leu Leu
                 335                 340                 345

 Ala Ala Ile Asn Ala Phe Arg Gln Val Arg Leu Lys His Arg Lys
                 350                 355                 360

 Leu Arg Glu Gln Val Asn Ser Met Val Asp Ile Ser Lys Met His
                 365                 370                 375

 Met Ile Leu Tyr Asp Leu Gln Gln Asn Leu Ser Ser Ser His Arg
                 380                 385                 390

 Ala Leu Glu Lys Gln Ile Asp Thr Leu Ala Gly Lys Leu Asp Ala
                 395                 400                 405

 Leu Thr Glu Leu Leu Ser Thr Ala Leu Gly Pro Arg Gln Leu Pro
                 410                 415                 420

 Glu Pro Ser Gln Gln Ser Lys
                 425

<210> 1129
<211> 1505
<212> DNA
<213> Homo sapien

<400> 1129
 ccacgtggtg gctttctcac gctagccctc tttggtcctc cttgacgtcc 50

 cgggcctgtg ggcccgcttt ctgccgagat gccgaaggtc aagtcggggg 100

 ccatcggccg ccgccgcggg cggcaggagc agcgccggga gctgaagagc 150

 gctggaggac tcatgttcaa cacggggatt gggcagcaca ttttgaaaaa 200

 tcctctcatt attaacagca ttatcgataa ggctgcctta agaccaactg 250

 atgtagtgct ggaagttgga cctggaactg gcaacatgac tgtaaagttg 300

 ttagaaaagg caaaaaaggt tgttgcttgt gaacttgacc caaggctagt 350

 agctgaactt cacaaaagag ttcagggcac gcctgtggcc agcaaacttc 400

 aagtactggt gggtgatgtg ctgaaaacag atttgccatt ctttgatact 450

 tgtgtggcaa atttgcctta tcagatctct tcgccttttg tcttcaagct 500

 gttgctacat cgaccttttt tcaggtgtgc tatacttatg tttcaaagag 550

 aatttgccct ccgactggtt gcaaaacctg gagataagtt atactgcaga 600

 ctctcaatta atacacagct gttggcacgt gtggaccatc taatgaaagt 650

 gggaaagaat aacttcagac caccgcccaa ggtggaatcc agtgttgtaa 700

 ggatagaacc taagaatcca ccaccaccca tcaattttca ggaatgggat 750

 ggtctagtaa ggataacctt tgttaggaaa aacaagacac tctctgctgc 800

 atttaaatca agtgcagtgc aacaactctt ggaaaaaaac tacagaattc 850

 actgttcagt ccataatatt ataataccag aagatttcag catagcagat 900

 aaaatacagc aaatcctaac cagcacaggt tttagtgaca aacgggcccg 950

 ttccatggac atagatgact tcatcagatt gctacatgga ttcaacgcag 1000

 aaggtattca tttttcctag gtatttggaa aacagaaatt ttcaaggtca 1050

 agaaaagaaa tgaattttgt attttttgta tttgagaaga taatgctttt 1100

 gctttactga gacattattt acttgactat ttttggttca atactactac 1150

 tgttgtcacc atttatgatt ctgaatttta aagttggaaa gttctaagta 1200

 tcaaagtttt taatatataa tgctggtcca atctattcat aataatcttc 1250

 aagttcagga gccgcagaga cgcacaactt tacacttatc atttctaaca 1300

 gtttattgta taaagatgtt actcttctat ttactgttat atactgtaag 1350

 gccttcttta ggcctttagc tctgttcctc cagtaataaa aaagttaaaa 1400

 tatgcttcac tagtcacaca ttccccatac catttcgtgt tattcacatt 1450

 ccccgtacca tttcttgtta ttcacatgta cagtaaaaca attgtttctt 1500

 aaatt 1505

<210> 1130
<211> 313
<212> PRT
<213> Homo sapien

<400> 1130
 Met Pro Lys Val Lys Ser Gly Ala Ile Gly Arg Arg Arg Gly Arg
   1               5                  10                  15

 Gln Glu Gln Arg Arg Glu Leu Lys Ser Ala Gly Gly Leu Met Phe
                  20                  25                  30

 Asn Thr Gly Ile Gly Gln His Ile Leu Lys Asn Pro Leu Ile Ile
                  35                  40                  45

 Asn Ser Ile Ile Asp Lys Ala Ala Leu Arg Pro Thr Asp Val Val
                  50                  55                  60

 Leu Glu Val Gly Pro Gly Thr Gly Asn Met Thr Val Lys Leu Leu
                  65                  70                  75

 Glu Lys Ala Lys Lys Val Val Ala Cys Glu Leu Asp Pro Arg Leu
                  80                  85                  90

 Val Ala Glu Leu His Lys Arg Val Gln Gly Thr Pro Val Ala Ser
                  95                 100                 105

 Lys Leu Gln Val Leu Val Gly Asp Val Leu Lys Thr Asp Leu Pro
                 110                 115                 120

 Phe Phe Asp Thr Cys Val Ala Asn Leu Pro Tyr Gln Ile Ser Ser
                 125                 130                 135

 Pro Phe Val Phe Lys Leu Leu Leu His Arg Pro Phe Phe Arg Cys
                 140                 145                 150

 Ala Ile Leu Met Phe Gln Arg Glu Phe Ala Leu Arg Leu Val Ala
                 155                 160                 165

 Lys Pro Gly Asp Lys Leu Tyr Cys Arg Leu Ser Ile Asn Thr Gln
                 170                 175                 180

 Leu Leu Ala Arg Val Asp His Leu Met Lys Val Gly Lys Asn Asn
                 185                 190                 195

 Phe Arg Pro Pro Pro Lys Val Glu Ser Ser Val Val Arg Ile Glu
                 200                 205                 210

 Pro Lys Asn Pro Pro Pro Pro Ile Asn Phe Gln Glu Trp Asp Gly
                 215                 220                 225

 Leu Val Arg Ile Thr Phe Val Arg Lys Asn Lys Thr Leu Ser Ala
                 230                 235                 240

 Ala Phe Lys Ser Ser Ala Val Gln Gln Leu Leu Glu Lys Asn Tyr
                 245                 250                 255

 Arg Ile His Cys Ser Val His Asn Ile Ile Ile Pro Glu Asp Phe
                 260                 265                 270

 Ser Ile Ala Asp Lys Ile Gln Gln Ile Leu Thr Ser Thr Gly Phe
                 275                 280                 285

 Ser Asp Lys Arg Ala Arg Ser Met Asp Ile Asp Asp Phe Ile Arg
                 290                 295                 300

 Leu Leu His Gly Phe Asn Ala Glu Gly Ile His Phe Ser
                 305                 310

<210> 1131
<211> 3674
<212> DNA
<213> Homo sapien

<400> 1131
 cagtagctaa ggaaaccagg tgtgggcggc tgggccttgc agctaaccct 50

 taaccctctg gcaacccgca gatagcccca actggcccca acagttccct 100

 ggggtccctt ttggatgggg ccaaggtgga gctgctagaa agattccttt 150

 ggggagatgg tcagaaatac ttcagttatt tattattttg ttatttttat 200

 tttttgctgt tgcctcctgg aaacggactt gaagtttctt cccctatatt 250

 ctttccctca gctcttgggg gccagaaatc ccaaagggag tccgctgccc 300

 cggccctcca gggccgcctc ctctgtttgc tttgcagagg agggaactgc 350

 tccttcgact ctgcagctca ggcctgtccc cgacacagcc cccagggagt 400

 cttctagcta cccctggcct ctaggccgcc tgacgctcag tgccttcctc 450

 cgttccgggg cctggtaccc gtgccgggca gccttacacc agccatgccc 500

 gcggcaccac atgtgtcttc tcactcgcga ggtcttgtgc ccagcgcccc 550

 cgggaaggcg ggggcgctca ccccacagcc caggccccgg ggttctgccc 600

 cacagtcctg cgtgggccac gtaggaagca gcgtgggggc tgtgtctgct 650

 gggaggtggc ttggatgggg aggacagccc ggcaccctga cccccgcccc 700

 tccccagccc tgcagtcccc cactgggccg gggagtctct ccagcttctc 750

 tctctctggt tattcaggag acacattttc ggccttaaaa ctggcatgga 800

 gcgcaggccc tcccttgcag aaaattatca aggaagaggg agttggcaga 850

 gtttctctgc cccggggctg gggacgcgga gctccgggga aattgttaaa 900

 tcagtgttct ggcgccccct gttgggggaa ctctggaatt acaggagtgg 950

 gccttggggg ggactgagct ccatccctct cccccgcccc acccccaccc 1000

 aaagttgccc accctgtttt tccgttgcat cgctggtctt gtgcttcccg 1050

 cttcagtctg ggagccaaga gccagcccca cctcccttca gaggacgcag 1100

 tgacttttgg actttccaga ggtggttctg tgtttctgcc cttggctcct 1150

 ctccgtcttg ggctggggca cttggagccc tctccatgtg gcgcccagtg 1200

 ttggggggag gcaggctcca gtggaggctg agtgaggcct ggtcccttcc 1250

 ccgtgccctc ctcggagctg ccacagaggc taagacggct gtcctgctgg 1300

 tgctggccct gctggatgtg gtattgaagt ctggggcagc tgatagcagg 1350

 aaggagaccc ccttggatgc tggtctcctg ggacctgaac agtctgtcag 1400

 caatggctgg aaatccttct tcctctggcc accccggggg tgccgggcaa 1450

 cccccttagc tctaagatgt ggccacaaat ctcttcccac tcctccccgc 1500

 caacctgaac agaaagtttt gaccttgcaa cctgtaagaa agaatccgtc 1550

 cgcatgactg tttacaagcg atagaaacac gtaagactct gtccccttga 1600

 gctcccaccc ccgggccggg gatgccccac ctggggtgac tgcactgtag 1650

 ctgcaaggcg tgttcttgca cgaagtgtga tcttatggcc ctgcgagagg 1700

 tgctcatcat catgcccatt ttctgctgtt tctgatgggt cagctacctc 1750

 acggcggggc cagctctgct gtcctggcaa gtgtcattga ctctctaaac 1800

 ttgaagtcct tcaggagccc tgagcccaac atccatgaga caccccgagt 1850

 tgtgcttcat gagagttgga ttctctgccc actctttcag ggatgtccaa 1900

 ggtccatgtt agggggcagg cccccagctc cactcactgc acaagcaccc 1950

 taaatgttgg aagcacaaaa tggttgtgat ttgagcacaa tggcagggtc 2000

 ctgcaggcag acttgacagg cccaggcccg ggaggatccc cccacgttgg 2050

 ctctgtccaa agtgagattg ggggtgcctg tgtctgggac agggggctgc 2100

 ccttgctcag accaggcctt ggctcatggc ttgtcctaat tctgggactc 2150

 gtcatcttac ttcttgccct tctgtgccca tcttaagact ggaggctgag 2200

 ccttgtcagg cccagccaca tctttacgcc atgggaccag gagtaaagcg 2250

 ctctctaaac cccgcacccc aaatctctaa acgcctgagt tcaggctgag 2300

 tcctagccct agtgagcctg aagagcttgg actgattccc agtctcctgg 2350

 gtcaagcccc actttgtgct ttcgaagctt atgagcgggt tccctggata 2400

 gaaggagtct tccatcccca ctgcccttgg gcctcttcag catagtcctg 2450

 tgccagggcc ctgtcctcac tatcagtcag ttcagtattt gctttcacgt 2500

 gagtggcgga ctcttctgaa gcagccagaa ctctcaaagg cagcgcatgg 2550

 agttgccttg cgagatttcc aaggaaggag gaaagattaa caggcggagc 2600

 ctggcacacc caagcctttg aggtggtcag agtgccacct tcagcccctt 2650

 gggaagggac agcggtgggt ctgggagtgg cctcaccctg gattcagcct 2700

 aggaatctct tcaccctcag ctgtccagcc ctgctgcctg tctggggatg 2750

 tgtggcctgg gcagagggca gtttaaagca caaaaccaca tggggaaaac 2800

 acaaggttgc ggggactttc tcatgtgcct gatgtggtgg agggagacac 2850

 cagcaggtgg ctgcagtgac gttagggaac ataacacttc tttgccctgc 2900

 tagctctcag ctctgggggg catcccccga tgtggtctgg gctgggagca 2950

 ggcatatccc ctggttgttg cctgtgcctg gtctgttcac catcgtgttt 3000

 gtgtgggcag agcctgccct gcaggagcag tgactttctt cccactgtgt 3050

 gtcccggacc tgtggtatgt gtccctttgc catcccaaac aggcaactgc 3100

 ttgctgctct ccttgcttgg catagcctcc tggtcagtgg ccaatgcccc 3150

 acaggccttc ctgggcctgg ccctcctctc ctgactccca gatccttccc 3200

 tgccctcttg tgtgcaagga cagattttgc agggaaagtt ctgtttcttc 3250

 tttgatacct ttgttctgtc ccctgcccca tccccagcac tcatgatctt 3300

 gaagccccta tcacactcta gttcagtcct gtgaaccatg tcctgagggc 3350

 cttgcaggga agtaggaaat agaaactcct ccacaaagag ccgaggatca 3400

 gagaagaccc ctgagatgaa tcagggccct gccctgccca ccaactcttt 3450

 tctagcaatc atgtcctgcc caggctgcag gcttcattag gctcctgctg 3500

 tcctccatga tgtgactagc acaaggtgta tatatgtttt gtacctctgc 3550

 cgatggctgt acatagtgta tgaaagttat ttaagcccca tgttgtacat 3600

 ttctgttcct agattggatg tgtgtgttct aagaagttgt cataaataaa 3650

 acctgaatga ccaaaaaaaa aaaa 3674

<210> 1132
<211> 253
<212> PRT
<213> Homo sapien

<400> 1132
 Met Glu Arg Arg Pro Ser Leu Ala Glu Asn Tyr Gln Gly Arg Gly
   1               5                  10                  15

 Ser Trp Gln Ser Phe Ser Ala Pro Gly Leu Gly Thr Arg Ser Ser
                  20                  25                  30

 Gly Glu Ile Val Lys Ser Val Phe Trp Arg Pro Leu Leu Gly Glu
                  35                  40                  45

 Leu Trp Asn Tyr Arg Ser Gly Pro Trp Gly Gly Leu Ser Ser Ile
                  50                  55                  60

 Pro Leu Pro Arg Pro Thr Pro Thr Gln Ser Cys Pro Pro Cys Phe
                  65                  70                  75

 Ser Val Ala Ser Leu Val Leu Cys Phe Pro Leu Gln Ser Gly Ser
                  80                  85                  90

 Gln Glu Pro Ala Pro Pro Pro Phe Arg Gly Arg Ser Asp Phe Trp
                  95                 100                 105

 Thr Phe Gln Arg Trp Phe Cys Val Ser Ala Leu Gly Ser Ser Pro
                 110                 115                 120

 Ser Trp Ala Gly Ala Leu Gly Ala Leu Ser Met Trp Arg Pro Val
                 125                 130                 135

 Leu Gly Gly Gly Arg Leu Gln Trp Arg Leu Ser Glu Ala Trp Ser
                 140                 145                 150

 Leu Pro Arg Ala Leu Leu Gly Ala Ala Thr Glu Ala Lys Thr Ala
                 155                 160                 165

 Val Leu Leu Val Leu Ala Leu Leu Asp Val Val Leu Lys Ser Gly
                 170                 175                 180

 Ala Ala Asp Ser Arg Lys Glu Thr Pro Leu Asp Ala Gly Leu Leu
                 185                 190                 195

 Gly Pro Glu Gln Ser Val Ser Asn Gly Trp Lys Ser Phe Phe Leu
                 200                 205                 210

 Trp Pro Pro Arg Gly Cys Arg Ala Thr Pro Leu Ala Leu Arg Cys
                 215                 220                 225

 Gly His Lys Ser Leu Pro Thr Pro Pro Arg Gln Pro Glu Gln Lys
                 230                 235                 240

 Val Leu Thr Leu Gln Pro Val Arg Lys Asn Pro Ser Ala
                 245                 250

<210> 1133
<211> 841
<212> DNA
<213> Homo sapien

<400> 1133
 gaaccgttta ctcgctgctg tgcccatcta tcagcaggct ccgggctgaa 50

 gattgcttct cttctctcct ccaaggtcta gtgacggagc ccgcgcgcgg 100

 cgccaccatg cggcagaagg cggtatcgct tttcttgtgc tacctgctgc 150

 tcttcacttg cagtggggtg gaggcaggtg agaatgcggg taaggatgca 200

 ggtaagaaaa agtgctcgga gagctcggac agcggctccg ggttctggaa 250

 ggccctgacc ttcatggccg tcggaggagg actcgcagtc gccgggctgc 300

 ccgcgctggg cttcaccggc gccggcatcg cggccaactc ggtggctgcc 350

 tcgctgatga gctggtctgc gatcctgaat gggggcggcg tgcccgccgg 400

 ggggctagtg gccacgctgc agagcctcgg ggctggtggc agcagcgtcg 450

 tcataggtaa tattggtgcc ctgatgggct acgccaccca caagtatctc 500

 gatagtgagg aggatgagga gtagccagca gctcccagaa cctcttcttc 550

 cttcttggcc taactcttcc agttaggatc tagaactttg cctttttttt 600

 tttttttttt tttttttgag atgggttctc actatattgt ccaggctaga 650

 gtgcagtggc tattcacaga tgcgaacata gtacactgca gcctccaact 700

 cctagcctca agtgatcctc ctgtctcaac ctcccaagta ggattacaag 750

 catgcgccga cgatgcccag aatccagaac tttgtctatc actctcccca 800

 acaacctaga tgtgaaaaca gaataaactt cacccagaaa a 841

<210> 1134
<211> 138
<212> PRT
<213> Homo sapien

<400> 1134
 Met Arg Gln Lys Ala Val Ser Leu Phe Leu Cys Tyr Leu Leu Leu
   1               5                  10                  15

 Phe Thr Cys Ser Gly Val Glu Ala Gly Glu Asn Ala Gly Lys Asp
                  20                  25                  30

 Ala Gly Lys Lys Lys Cys Ser Glu Ser Ser Asp Ser Gly Ser Gly
                  35                  40                  45

 Phe Trp Lys Ala Leu Thr Phe Met Ala Val Gly Gly Gly Leu Ala
                  50                  55                  60

 Val Ala Gly Leu Pro Ala Leu Gly Phe Thr Gly Ala Gly Ile Ala
                  65                  70                  75

 Ala Asn Ser Val Ala Ala Ser Leu Met Ser Trp Ser Ala Ile Leu
                  80                  85                  90

 Asn Gly Gly Gly Val Pro Ala Gly Gly Leu Val Ala Thr Leu Gln
                  95                 100                 105

 Ser Leu Gly Ala Gly Gly Ser Ser Val Val Ile Gly Asn Ile Gly
                 110                 115                 120

 Ala Leu Met Gly Tyr Ala Thr His Lys Tyr Leu Asp Ser Glu Glu
                 125                 130                 135

 Asp Glu Glu


<210> 1135
<211> 2058
<212> DNA
<213> Homo sapien

<400> 1135
 gcacgaggaa gccacagatc tcttaagaac tttctgtctc caaaccgtgg 50

 ctgctcgata aatcagacag aacagttaat cctcaattta agcctgatct 100

 aacccctaga aacagatata gaacaatgga agtgacaaca agattgacat 150

 ggaatgatga aaatcatctg cgcaactgct tggaaatgtt tctttgagtc 200

 ttctctataa gtctagtgtt catggaggta gcattgaaga tatggttgaa 250

 agatgcagcc gtcagggatg tactataaca atggcttaca ttgattacaa 300

 tatgattgta gcctttatgc ttggaaatta tattaattta cgtgaaagtt 350

 ctacagagcc aaatgattcc ctatggtttt cacttcaaaa gaaaaatgac 400

 accactgaaa tagaaacttt actcttaaat acagcaccaa aaattattga 450

 tgagcaactg gtgtgtcgtt tatcgaaaac ggatattttc attatatgtc 500

 gagataataa aatttatcta gataaaatga taacaagaaa cttgaaacta 550

 aggttttatg gccaccgtca gtatttggaa tgtgaagttt ttcgagttga 600

 aggaattaag gataacctag acgacataaa gaggataatt aaagccagag 650

 agcacagaaa taggcttcta gcagacatca gagactatag gccctatgca 700

 gacttggttt cagaaattcg tattcttttg gtgggtccag ttgggtctgg 750

 aaagtccagt tttttcaatt cagtcaagtc tatttttcat ggccatgtga 800

 ctggccaagc cgtagtgggg tctgatacca ccagcataac cgagcggtat 850

 aggatatatt ctgttaaaga tggaaaaaat ggaaaatctc tgccatttat 900

 gttgtgtgac actatggggc tagatggggc agaaggagca ggactgtgca 950

 tggatgacat tccccacatc ttaaaaggtt gtatgccaga cagatatcag 1000

 tttaattccc gtaaaccaat tacacctgag cattctactt ttatcacctc 1050

 tccatctctg aaggacagga ttcactgtgt ggcttatgtc ttagacatca 1100

 actctattga caatctctac tctaaaatgt tggcaaaagt gaagcaagtt 1150

 cacaaagaag tattaaactg tggtatagca tatgtggcct tgcttactaa 1200

 agtggatgat tgcagtgagg ttcttcaaga caacttttta aacatgagta 1250

 gatctatgac ttctcaaagc cgggtcatga atgtccataa aatgctaggc 1300

 attcctattt ccaatatttt gatggttgga aattatgctt cagatttgga 1350

 actggacccc atgaaggata ttctcatcct ctctgcactg aggcagatgc 1400

 tgcgggctgc agatgatttt ttagaagatt tgcctcttga ggaaactggt 1450

 gcaattgaga gagcgttaca gccctgcatt tgagataagt tgccttgatt 1500

 ctgacatttg gcccagcctg tactggtgtg ccgcaatgag agtcaatctc 1550

 tattgacagc ctgcttcaga ttttgctttt gttcgttttg ccttctgtcc 1600

 ttggaacagt catatctcaa gttcaaaggc caaaacctga gaagcggtgg 1650

 gctaagatag gtcctactgc aaaccacccc tccatatttc cgtaccattt 1700

 acaattcagt ttctgtgaca tctttttaaa ccactggagg aaaaatgaga 1750

 tattctctaa tttattcttc tataacactc tatatagagc tatgtgagta 1800

 ctaatcacat tgaataatag ttataaaatt attgtataga catctgcttc 1850

 ttaaacagat tgtgagttct ttgagaaaca gcgtggattt tacttatctg 1900

 tgtattcaca gagcttagca cagtgcctgg taatgagcaa gcatacttgc 1950

 cattactttt ccttcccact ctctccaaca tcacattcac tttaaatttt 2000

 tctgtatata gaaaggaaaa ctagcctggg caacatgatg aaaccccatc 2050

 tccactgc 2058

<210> 1136
<211> 413
<212> PRT
<213> Homo sapien

<400> 1136
 Met Val Glu Arg Cys Ser Arg Gln Gly Cys Thr Ile Thr Met Ala
   1               5                  10                  15

 Tyr Ile Asp Tyr Asn Met Ile Val Ala Phe Met Leu Gly Asn Tyr
                  20                  25                  30

 Ile Asn Leu Arg Glu Ser Ser Thr Glu Pro Asn Asp Ser Leu Trp
                  35                  40                  45

 Phe Ser Leu Gln Lys Lys Asn Asp Thr Thr Glu Ile Glu Thr Leu
                  50                  55                  60

 Leu Leu Asn Thr Ala Pro Lys Ile Ile Asp Glu Gln Leu Val Cys
                  65                  70                  75

 Arg Leu Ser Lys Thr Asp Ile Phe Ile Ile Cys Arg Asp Asn Lys
                  80                  85                  90

 Ile Tyr Leu Asp Lys Met Ile Thr Arg Asn Leu Lys Leu Arg Phe
                  95                 100                 105

 Tyr Gly His Arg Gln Tyr Leu Glu Cys Glu Val Phe Arg Val Glu
                 110                 115                 120

 Gly Ile Lys Asp Asn Leu Asp Asp Ile Lys Arg Ile Ile Lys Ala
                 125                 130                 135

 Arg Glu His Arg Asn Arg Leu Leu Ala Asp Ile Arg Asp Tyr Arg
                 140                 145                 150

 Pro Tyr Ala Asp Leu Val Ser Glu Ile Arg Ile Leu Leu Val Gly
                 155                 160                 165

 Pro Val Gly Ser Gly Lys Ser Ser Phe Phe Asn Ser Val Lys Ser
                 170                 175                 180

 Ile Phe His Gly His Val Thr Gly Gln Ala Val Val Gly Ser Asp
                 185                 190                 195

 Thr Thr Ser Ile Thr Glu Arg Tyr Arg Ile Tyr Ser Val Lys Asp
                 200                 205                 210

 Gly Lys Asn Gly Lys Ser Leu Pro Phe Met Leu Cys Asp Thr Met
                 215                 220                 225

 Gly Leu Asp Gly Ala Glu Gly Ala Gly Leu Cys Met Asp Asp Ile
                 230                 235                 240

 Pro His Ile Leu Lys Gly Cys Met Pro Asp Arg Tyr Gln Phe Asn
                 245                 250                 255

 Ser Arg Lys Pro Ile Thr Pro Glu His Ser Thr Phe Ile Thr Ser
                 260                 265                 270

 Pro Ser Leu Lys Asp Arg Ile His Cys Val Ala Tyr Val Leu Asp
                 275                 280                 285

 Ile Asn Ser Ile Asp Asn Leu Tyr Ser Lys Met Leu Ala Lys Val
                 290                 295                 300

 Lys Gln Val His Lys Glu Val Leu Asn Cys Gly Ile Ala Tyr Val
                 305                 310                 315

 Ala Leu Leu Thr Lys Val Asp Asp Cys Ser Glu Val Leu Gln Asp
                 320                 325                 330

 Asn Phe Leu Asn Met Ser Arg Ser Met Thr Ser Gln Ser Arg Val
                 335                 340                 345

 Met Asn Val His Lys Met Leu Gly Ile Pro Ile Ser Asn Ile Leu
                 350                 355                 360

 Met Val Gly Asn Tyr Ala Ser Asp Leu Glu Leu Asp Pro Met Lys
                 365                 370                 375

 Asp Ile Leu Ile Leu Ser Ala Leu Arg Gln Met Leu Arg Ala Ala
                 380                 385                 390

 Asp Asp Phe Leu Glu Asp Leu Pro Leu Glu Glu Thr Gly Ala Ile
                 395                 400                 405

 Glu Arg Ala Leu Gln Pro Cys Ile
                 410

<210> 1137
<211> 4908
<212> DNA
<213> Homo sapien

<400> 1137
 acctgcgtgc agtcggtcct ccaggccacg cagcgcccga gagtaccagg 50

 gagactccgg cccctgtcgg cgccaagccc ctccgcccct cacagcgccc 100

 aggtccgcgg ccgggccttg attttttggc ggggaccgtc atggcgtcgc 150

 agccaaattc gtctgcgaag aagaaagagg agaaggggaa gaacatccag 200

 gtggtggtga gatgcagacc atttaatttg gcagagcgga aagctagcgc 250

 ccattcaata gtagaatgtg atcctgtacg aaaagaagtt agtgtacgaa 300

 ctggaggatt ggctgacaag agctcaagga aaacatacac ttttgatatg 350

 gtgtttggag catctactaa acagattgat gtttaccgaa gtgttgtttg 400

 tccaattctg gatgaagtta ttatgggcta taattgcact atctttgcgt 450

 atggccaaac tggcactgga aaaactttta caatggaagg tgaaaggtca 500

 cctaatgaag agtatacctg ggaagaggat cccttggctg gtataattcc 550

 acgtaccctt catcaaattt ttgagaaact tactgataat ggtactgaat 600

 tttcagtcaa agtgtctctg ttggagatct ataatgaaga gctttttgat 650

 cttcttaatc catcatctga tgtttctgag agactacaga tgtttgatga 700

 tccccgtaac aagagaggag tgataattaa aggtttagaa gaaattacag 750

 tacacaacaa ggatgaagtc tatcaaattt tagaaaaggg ggcagcaaaa 800

 aggacaactg cagctactct gatgaatgca tactctagtc gttcccactc 850

 agttttctct gttacaatac atatgaaaga aactacgatt gatggagaag 900

 agcttgttaa aatcggaaag ttgaacttgg ttgatcttgc aggaagtgaa 950

 aacattggcc gttctggagc tgttgataag agagctcggg aagctggaaa 1000

 tataaatcaa tccctgttga ctttgggaag ggtcattact gcccttgtag 1050

 aaagaacacc tcatgttcct tatcgagaat ctaaactaac tagaatcctc 1100

 caggattctc ttggagggcg tacaagaaca tctataattg caacaatttc 1150

 tcctgcatct ctcaatcttg aggaaactct gagtacattg gaatatgctc 1200

 atagagcaaa gaacatattg aataagcctg aagtgaatca gaaactcacc 1250

 aaaaaagctc ttattaagga gtatacggag gagatagaac gtttaaaacg 1300

 agatcttgct gcagcccgtg agaaaaatgg agtgtatatt tctgaagaaa 1350

 attttagagt catgagtgga aaattaactg ttcaagaaga gcagattgta 1400

 gaattgattg aaaaaattgg tgctgttgag gaggagctga atagggttac 1450

 agagttgttt atggataata aaaatgaact tgaccagtgt aaatctgacc 1500

 tgcaaaataa aacacaagaa cttgaaacca ctcaaaaaca tttgcaagaa 1550

 actaaattac aacttgttaa agaagaatat atcacatcag ctttggaaag 1600

 tactgaggag aaacttcatg atgctgccag caagctgctt aacacagttg 1650

 aagaaactac aaaagatgta tctggtctcc attccaaact ggatcgtaag 1700

 aaggcagttg accaacacaa tgcagaagct caggatattt ttggcaaaaa 1750

 cctgaatagt ctgtttaata atatggaaga attaattaag gatggcagct 1800

 caaagcaaaa ggccatgcta gaagtacata agaccttatt tggtaatctg 1850

 ctgtcttcca gtgtctctgc attagatacc attactacag tagcacttgg 1900

 atctctcaca tctattccag aaaatgtgtc tactcatgtt tctcagattt 1950

 ttaatatgat actaaaagaa caatcattag cagcagaaag taaaactgta 2000

 ctacaggaat tgattaatgt actcaagact gatcttctaa gttcactgga 2050

 aatgatttta tccccaactg tggtgtctat actgaaaatc aatagtcaac 2100

 taaagcatat tttcaagact tcattgacag tggccgataa gatagaagat 2150

 caaaaaaagg aactagatgg ctttctcagt atactgtgta acaatctaca 2200

 tgaactacaa gaaaatacca tttgttcctt ggttgagtca caaaagcaat 2250

 gtggaaacct aactgaagac ctgaagacaa taaagcagac ccattcccag 2300

 gaactttgca agttaatgaa tctttggaca gagagattct gtgctttgga 2350

 ggaaaagtgt gaaaatatac agaaaccact tagtagtgtc caggaaaata 2400

 tacagcagaa atctaaggat atagtcaaca aaatgacttt tcacagtcaa 2450

 aaattttgtg ctgattctga tggcttctca caggaactca gaaattttaa 2500

 ccaagaaggt acaaaattgg ttgaagaatc tgtgaaacac tctgataaac 2550

 tcaatggcaa cctggaaaaa atatctcaag agactgaaca gagatgtgaa 2600

 tctctgaaca caagaacagt ttatttttct gaacagtggg tatcttcctt 2650

 aaatgaaagg gaacaggaac ttcacaactt attggaggtt gtaagccaat 2700

 gttgtgaggc ttcaagttca gacatcactg agaaatcaga tggacgtaag 2750

 gcagctcatg agaaacagca taacattttt cttgatcaga tgactattga 2800

 tgaagataaa ttgatagcac aaaatctaga acttaatgaa accataaaaa 2850

 ttggtttgac taagcttaat tgctttctgg aacaggatct gaaactggat 2900

 atcccaacag gtacgacacc acagaggaaa agttatttat acccatcaac 2950

 actggtaaga actgaaccac gtgaacatct ccttgatcag ctgaaaagga 3000

 aacagcctga gctgttaatg atgctaaact gttcagaaaa caacaaagaa 3050

 gagacaattc cggatgtgga tgtagaagag gcagttctgg ggcagtatac 3100

 tgaagaacct ctaagtcaag agccatctgt agatgctggt gtggattgtt 3150

 catcaattgg cggggttcca tttttccagc ataaaaaatc acatggaaaa 3200

 gacaaagaaa acagaggcat taacacactg gagaggtcta aagtggaaga 3250

 aactacagag cacttggtta caaagagcag attacctctg cgagcccaga 3300

 tcaaccttta attcacttgg gggttggcaa ttttattttt aaagaaaact 3350

 taaaaataaa acctgaaacc ccagaacttg agccttgtgt atagatttta 3400

 aaagaatata tatatcagcc gggcgcggtg gctcatgcct gtaatcccag 3450

 cactttggga ggctgaggcg ggtggattgc ttgagcccag gagtttgaga 3500

 ccagcctggc caacgtggca aaacctcgtc tctgttaaaa attagccggg 3550

 cgtggtggca cactcctgta atcccagcta ctggggaggc tgaggcacga 3600

 gaatcacttg aacccaggaa gcggggttgc agtgagccaa aggtacacca 3650

 ctacactcca gcctgggcaa cagagcaaga ctcggtctca aaaacaaaat 3700

 ttaaaaaaga tataaggcag tactgtaaat tcagttgaat tttgatatct 3750

 acccattttt ctgtcatccc tatagttcac tttgtattaa attgggtttc 3800

 atttgggatt tgcaatgtaa atacgtattt ctagttttca tataaagtag 3850

 ttcttttata acaaatgaaa agtatttttc ttgtatatta ttaagtaatg 3900

 aatatataag aactgtactc ttctcagctt gagcttaaca taggtaaata 3950

 tcaccaacat ctgtccttag aaaggaccat ctcatgtttt ttttcttgct 4000

 atgacttgtg tattttcttg catcctccct agacttccct atttcgcttt 4050

 ctcctcggct cactttctcc ctttttattt ttcaccaaac catttgtaga 4100

 gctacaaaac ctatcctttc ttattttcag tagtcagaat tttatctaga 4150

 aatcttttaa caccttttta gtggttattt ctaaaatcac tgtcaacaat 4200

 aaatctaacc ctagttgtat ccctccttta agtatttaaa acttgttgcc 4250

 ccaaatgtga aagcatttaa ttcctttaag aggcctaact cattcaccct 4300

 gacagagttc acaaaaagcc cactttagag tatacattgc tattatggga 4350

 gaccacccag acatctgact aatggctctg tgccacactc caagacctgt 4400

 gccttttaga gaagctcaca atgatttaag gactgtttga aacttccaat 4450

 tatgtctata atttatattc ttttgtttac atgatgaaac tttttgttgt 4500

 tgcttgtttg tatataatac aatgtgtaca tgtatctttt tctcgattca 4550

 aatcttaacc cttaggactc tggtattttt gatctggcaa ccatatttct 4600

 ggaagttgag atgtttcagc ttgaagaacc aaaacagaag gaatatgtac 4650

 aaagaataaa ttttctgctc acgatgagtt tagtgtgtaa agtttagaga 4700

 catctgactt tgatagctaa attaaaccaa accctattga agaattgaat 4750

 atatgctact tcaagaaact aaattgatct cgtagaatta tcttaataaa 4800

 ataatggcta taatttctct gcaaaatcag atgtcagcat aagcgatgga 4850

 taatacctaa taaactgccc tcagtaaatc catggttaat aaatgtggtt 4900

 tctacatt 4908

<210> 1138
<211> 1056
<212> PRT
<213> Homo sapien

<400> 1138
 Met Ala Ser Gln Pro Asn Ser Ser Ala Lys Lys Lys Glu Glu Lys
   1               5                  10                  15

 Gly Lys Asn Ile Gln Val Val Val Arg Cys Arg Pro Phe Asn Leu
                  20                  25                  30

 Ala Glu Arg Lys Ala Ser Ala His Ser Ile Val Glu Cys Asp Pro
                  35                  40                  45

 Val Arg Lys Glu Val Ser Val Arg Thr Gly Gly Leu Ala Asp Lys
                  50                  55                  60

 Ser Ser Arg Lys Thr Tyr Thr Phe Asp Met Val Phe Gly Ala Ser
                  65                  70                  75

 Thr Lys Gln Ile Asp Val Tyr Arg Ser Val Val Cys Pro Ile Leu
                  80                  85                  90

 Asp Glu Val Ile Met Gly Tyr Asn Cys Thr Ile Phe Ala Tyr Gly
                  95                 100                 105

 Gln Thr Gly Thr Gly Lys Thr Phe Thr Met Glu Gly Glu Arg Ser
                 110                 115                 120

 Pro Asn Glu Glu Tyr Thr Trp Glu Glu Asp Pro Leu Ala Gly Ile
                 125                 130                 135

 Ile Pro Arg Thr Leu His Gln Ile Phe Glu Lys Leu Thr Asp Asn
                 140                 145                 150

 Gly Thr Glu Phe Ser Val Lys Val Ser Leu Leu Glu Ile Tyr Asn
                 155                 160                 165

 Glu Glu Leu Phe Asp Leu Leu Asn Pro Ser Ser Asp Val Ser Glu
                 170                 175                 180

 Arg Leu Gln Met Phe Asp Asp Pro Arg Asn Lys Arg Gly Val Ile
                 185                 190                 195

 Ile Lys Gly Leu Glu Glu Ile Thr Val His Asn Lys Asp Glu Val
                 200                 205                 210

 Tyr Gln Ile Leu Glu Lys Gly Ala Ala Lys Arg Thr Thr Ala Ala
                 215                 220                 225

 Thr Leu Met Asn Ala Tyr Ser Ser Arg Ser His Ser Val Phe Ser
                 230                 235                 240

 Val Thr Ile His Met Lys Glu Thr Thr Ile Asp Gly Glu Glu Leu
                 245                 250                 255

 Val Lys Ile Gly Lys Leu Asn Leu Val Asp Leu Ala Gly Ser Glu
                 260                 265                 270

 Asn Ile Gly Arg Ser Gly Ala Val Asp Lys Arg Ala Arg Glu Ala
                 275                 280                 285

 Gly Asn Ile Asn Gln Ser Leu Leu Thr Leu Gly Arg Val Ile Thr
                 290                 295                 300

 Ala Leu Val Glu Arg Thr Pro His Val Pro Tyr Arg Glu Ser Lys
                 305                 310                 315

 Leu Thr Arg Ile Leu Gln Asp Ser Leu Gly Gly Arg Thr Arg Thr
                 320                 325                 330

 Ser Ile Ile Ala Thr Ile Ser Pro Ala Ser Leu Asn Leu Glu Glu
                 335                 340                 345

 Thr Leu Ser Thr Leu Glu Tyr Ala His Arg Ala Lys Asn Ile Leu
                 350                 355                 360

 Asn Lys Pro Glu Val Asn Gln Lys Leu Thr Lys Lys Ala Leu Ile
                 365                 370                 375

 Lys Glu Tyr Thr Glu Glu Ile Glu Arg Leu Lys Arg Asp Leu Ala
                 380                 385                 390

 Ala Ala Arg Glu Lys Asn Gly Val Tyr Ile Ser Glu Glu Asn Phe
                 395                 400                 405

 Arg Val Met Ser Gly Lys Leu Thr Val Gln Glu Glu Gln Ile Val
                 410                 415                 420

 Glu Leu Ile Glu Lys Ile Gly Ala Val Glu Glu Glu Leu Asn Arg
                 425                 430                 435

 Val Thr Glu Leu Phe Met Asp Asn Lys Asn Glu Leu Asp Gln Cys
                 440                 445                 450

 Lys Ser Asp Leu Gln Asn Lys Thr Gln Glu Leu Glu Thr Thr Gln
                 455                 460                 465

 Lys His Leu Gln Glu Thr Lys Leu Gln Leu Val Lys Glu Glu Tyr
                 470                 475                 480

 Ile Thr Ser Ala Leu Glu Ser Thr Glu Glu Lys Leu His Asp Ala
                 485                 490                 495

 Ala Ser Lys Leu Leu Asn Thr Val Glu Glu Thr Thr Lys Asp Val
                 500                 505                 510

 Ser Gly Leu His Ser Lys Leu Asp Arg Lys Lys Ala Val Asp Gln
                 515                 520                 525

 His Asn Ala Glu Ala Gln Asp Ile Phe Gly Lys Asn Leu Asn Ser
                 530                 535                 540

 Leu Phe Asn Asn Met Glu Glu Leu Ile Lys Asp Gly Ser Ser Lys
                 545                 550                 555

 Gln Lys Ala Met Leu Glu Val His Lys Thr Leu Phe Gly Asn Leu
                 560                 565                 570

 Leu Ser Ser Ser Val Ser Ala Leu Asp Thr Ile Thr Thr Val Ala
                 575                 580                 585

 Leu Gly Ser Leu Thr Ser Ile Pro Glu Asn Val Ser Thr His Val
                 590                 595                 600

 Ser Gln Ile Phe Asn Met Ile Leu Lys Glu Gln Ser Leu Ala Ala
                 605                 610                 615

 Glu Ser Lys Thr Val Leu Gln Glu Leu Ile Asn Val Leu Lys Thr
                 620                 625                 630

 Asp Leu Leu Ser Ser Leu Glu Met Ile Leu Ser Pro Thr Val Val
                 635                 640                 645

 Ser Ile Leu Lys Ile Asn Ser Gln Leu Lys His Ile Phe Lys Thr
                 650                 655                 660

 Ser Leu Thr Val Ala Asp Lys Ile Glu Asp Gln Lys Lys Glu Leu
                 665                 670                 675

 Asp Gly Phe Leu Ser Ile Leu Cys Asn Asn Leu His Glu Leu Gln
                 680                 685                 690

 Glu Asn Thr Ile Cys Ser Leu Val Glu Ser Gln Lys Gln Cys Gly
                 695                 700                 705

 Asn Leu Thr Glu Asp Leu Lys Thr Ile Lys Gln Thr His Ser Gln
                 710                 715                 720

 Glu Leu Cys Lys Leu Met Asn Leu Trp Thr Glu Arg Phe Cys Ala
                 725                 730                 735

 Leu Glu Glu Lys Cys Glu Asn Ile Gln Lys Pro Leu Ser Ser Val
                 740                 745                 750

 Gln Glu Asn Ile Gln Gln Lys Ser Lys Asp Ile Val Asn Lys Met
                 755                 760                 765

 Thr Phe His Ser Gln Lys Phe Cys Ala Asp Ser Asp Gly Phe Ser
                 770                 775                 780

 Gln Glu Leu Arg Asn Phe Asn Gln Glu Gly Thr Lys Leu Val Glu
                 785                 790                 795

 Glu Ser Val Lys His Ser Asp Lys Leu Asn Gly Asn Leu Glu Lys
                 800                 805                 810

 Ile Ser Gln Glu Thr Glu Gln Arg Cys Glu Ser Leu Asn Thr Arg
                 815                 820                 825

 Thr Val Tyr Phe Ser Glu Gln Trp Val Ser Ser Leu Asn Glu Arg
                 830                 835                 840

 Glu Gln Glu Leu His Asn Leu Leu Glu Val Val Ser Gln Cys Cys
                 845                 850                 855

 Glu Ala Ser Ser Ser Asp Ile Thr Glu Lys Ser Asp Gly Arg Lys
                 860                 865                 870

 Ala Ala His Glu Lys Gln His Asn Ile Phe Leu Asp Gln Met Thr
                 875                 880                 885

 Ile Asp Glu Asp Lys Leu Ile Ala Gln Asn Leu Glu Leu Asn Glu
                 890                 895                 900

 Thr Ile Lys Ile Gly Leu Thr Lys Leu Asn Cys Phe Leu Glu Gln
                 905                 910                 915

 Asp Leu Lys Leu Asp Ile Pro Thr Gly Thr Thr Pro Gln Arg Lys
                 920                 925                 930

 Ser Tyr Leu Tyr Pro Ser Thr Leu Val Arg Thr Glu Pro Arg Glu
                 935                 940                 945

 His Leu Leu Asp Gln Leu Lys Arg Lys Gln Pro Glu Leu Leu Met
                 950                 955                 960

 Met Leu Asn Cys Ser Glu Asn Asn Lys Glu Glu Thr Ile Pro Asp
                 965                 970                 975

 Val Asp Val Glu Glu Ala Val Leu Gly Gln Tyr Thr Glu Glu Pro
                 980                 985                 990

 Leu Ser Gln Glu Pro Ser Val Asp Ala Gly Val Asp Cys Ser Ser
                 995                1000                1005

 Ile Gly Gly Val Pro Phe Phe Gln His Lys Lys Ser His Gly Lys
                1010                1015                1020

 Asp Lys Glu Asn Arg Gly Ile Asn Thr Leu Glu Arg Ser Lys Val
                1025                1030                1035

 Glu Glu Thr Thr Glu His Leu Val Thr Lys Ser Arg Leu Pro Leu
                1040                1045                1050

 Arg Ala Gln Ile Asn Leu
                1055

<210> 1139
<211> 1978
<212> DNA
<213> Homo sapien

<400> 1139
 cggaagccga ctcaacagag ctatggcggg tttgactgtg agagacccag 50

 cggtggatcg ttctctacgt tctgtgttcg tggggaacat tccttatgaa 100

 gctactgaag agcagttgaa ggacatcttt tctgaggttg gacctgttgt 150

 tagtttcaga ttggtatacg atagagagac aggaaagcca aagggttatg 200

 gcttctgtga ataccaagac caagagacag cacttagtgc catgcggaac 250

 ctgaatgggc gcgaattcag tgggagagca cttcgagtgg acaatgctgc 300

 cagtgaaaag aacaaagaag agctgaagag ccttggcact ggtgcccctg 350

 tcattgagtc accttatgga gagaccatca gtcctgagga tgcccctgag 400

 tccattagca aagcagttgc cagccttcca ccagagcaga tgtttgagct 450

 gatgaaacaa atgaagctct gtgtccagaa tagtccccag gaggcacgga 500

 acatgttact tcagaaccct caactggctt atgctttgct gcaagcacag 550

 gtagtgatga gaattgtgga tccggaaatt gccctgaaaa ttctgcatcg 600

 ccagacaaat atcccaacgc tgattgcagg caaccctcag ccagtccatg 650

 gtgctgggcc tggctcagga tccaatgtgt caatgaacca gcagaatcct 700

 caggcccctc aggcccagtc tttgggtgga atgcatgtca atggcgcacc 750

 tcctctgatg caagcttcta tgcagggtgg agttccagca ccagggcaaa 800

 tgccagctgc tgtcacagga cctggccctg gttccttagc tcctggagga 850

 ggaatgcagg ctcaggttgg aatgccagga agtggaccag tgtccatgga 900

 acgggggcaa gtgccgatgc aagaccccag agcagctatg cagcggggat 950

 ccttgcctgc gaatgtccca acccctcgag gcttgttagg agatgctccg 1000

 aatgatccac ggggaggcac tttactttct gtaactggag aggtagagcc 1050

 tagaggttac ttgggaccac ctcatcaggg tccacccatg caccatgtcc 1100

 ctggccatga gagccgagga ccacccccac atgaactgag gggagggcca 1150

 ttacccgagc ccagacctct aatggcagaa ccaagaggac ccatgctaga 1200

 tcagaggggt ccacccttgg atggcagagg tggaagggat ccccgaggaa 1250

 tagatgcacg agggatggag gcccgagcca tggaggcaag agggttagat 1300

 gccagaggat tagaggcccg tgcaatggag gcccgtgcga tggaagctcg 1350

 tgcaatggag gcccgagcga tggaggcccg tgcaatggaa gtccgaggga 1400

 tggaggccag aggcatggat accagaggcc cagtgcctgg ccccagagga 1450

 cctataccta gtggaatgca gggtcccagt ccaattaaca tgggggcggt 1500

 tgtcccccag ggatccagac aggtcccagt catgcaggga acaggaatgc 1550

 aaggagcaag tatacagggt ggaagccagc ctggcggctt tagtcccggg 1600

 cagaaccaag tcactccaca ggatcatgag aaggctgctt tgattatgca 1650

 ggttctacaa ctgactgcag accagattgc catgttgcct cctgagcaaa 1700

 ggcagagtat cctgatttta aaggaacaaa tacagaaatc cactggagca 1750

 ccttgatagg ttttcaaaaa tacctggcaa gaaatctgga aattctataa 1800

 ttttgttgaa atattgaaaa aagatgacct gcatcctaac ccttgaatga 1850

 ctcaaatcag tgccaggtgg aggactccca tcaccttctc tcagaacaaa 1900

 atcacttcat tttattgtct tagtttgtat attttctgtg acttgaaata 1950

 aactttgaac acaattttag tacactgc 1978

<210> 1140
<211> 577
<212> PRT
<213> Homo sapien

<400> 1140
 Met Ala Gly Leu Thr Val Arg Asp Pro Ala Val Asp Arg Ser Leu
   1               5                  10                  15

 Arg Ser Val Phe Val Gly Asn Ile Pro Tyr Glu Ala Thr Glu Glu
                  20                  25                  30

 Gln Leu Lys Asp Ile Phe Ser Glu Val Gly Pro Val Val Ser Phe
                  35                  40                  45

 Arg Leu Val Tyr Asp Arg Glu Thr Gly Lys Pro Lys Gly Tyr Gly
                  50                  55                  60

 Phe Cys Glu Tyr Gln Asp Gln Glu Thr Ala Leu Ser Ala Met Arg
                  65                  70                  75

 Asn Leu Asn Gly Arg Glu Phe Ser Gly Arg Ala Leu Arg Val Asp
                  80                  85                  90

 Asn Ala Ala Ser Glu Lys Asn Lys Glu Glu Leu Lys Ser Leu Gly
                  95                 100                 105

 Thr Gly Ala Pro Val Ile Glu Ser Pro Tyr Gly Glu Thr Ile Ser
                 110                 115                 120

 Pro Glu Asp Ala Pro Glu Ser Ile Ser Lys Ala Val Ala Ser Leu
                 125                 130                 135

 Pro Pro Glu Gln Met Phe Glu Leu Met Lys Gln Met Lys Leu Cys
                 140                 145                 150

 Val Gln Asn Ser Pro Gln Glu Ala Arg Asn Met Leu Leu Gln Asn
                 155                 160                 165

 Pro Gln Leu Ala Tyr Ala Leu Leu Gln Ala Gln Val Val Met Arg
                 170                 175                 180

 Ile Val Asp Pro Glu Ile Ala Leu Lys Ile Leu His Arg Gln Thr
                 185                 190                 195

 Asn Ile Pro Thr Leu Ile Ala Gly Asn Pro Gln Pro Val His Gly
                 200                 205                 210

 Ala Gly Pro Gly Ser Gly Ser Asn Val Ser Met Asn Gln Gln Asn
                 215                 220                 225

 Pro Gln Ala Pro Gln Ala Gln Ser Leu Gly Gly Met His Val Asn
                 230                 235                 240

 Gly Ala Pro Pro Leu Met Gln Ala Ser Met Gln Gly Gly Val Pro
                 245                 250                 255

 Ala Pro Gly Gln Met Pro Ala Ala Val Thr Gly Pro Gly Pro Gly
                 260                 265                 270

 Ser Leu Ala Pro Gly Gly Gly Met Gln Ala Gln Val Gly Met Pro
                 275                 280                 285

 Gly Ser Gly Pro Val Ser Met Glu Arg Gly Gln Val Pro Met Gln
                 290                 295                 300

 Asp Pro Arg Ala Ala Met Gln Arg Gly Ser Leu Pro Ala Asn Val
                 305                 310                 315

 Pro Thr Pro Arg Gly Leu Leu Gly Asp Ala Pro Asn Asp Pro Arg
                 320                 325                 330

 Gly Gly Thr Leu Leu Ser Val Thr Gly Glu Val Glu Pro Arg Gly
                 335                 340                 345

 Tyr Leu Gly Pro Pro His Gln Gly Pro Pro Met His His Val Pro
                 350                 355                 360

 Gly His Glu Ser Arg Gly Pro Pro Pro His Glu Leu Arg Gly Gly
                 365                 370                 375

 Pro Leu Pro Glu Pro Arg Pro Leu Met Ala Glu Pro Arg Gly Pro
                 380                 385                 390

 Met Leu Asp Gln Arg Gly Pro Pro Leu Asp Gly Arg Gly Gly Arg
                 395                 400                 405

 Asp Pro Arg Gly Ile Asp Ala Arg Gly Met Glu Ala Arg Ala Met
                 410                 415                 420

 Glu Ala Arg Gly Leu Asp Ala Arg Gly Leu Glu Ala Arg Ala Met
                 425                 430                 435

 Glu Ala Arg Ala Met Glu Ala Arg Ala Met Glu Ala Arg Ala Met
                 440                 445                 450

 Glu Ala Arg Ala Met Glu Val Arg Gly Met Glu Ala Arg Gly Met
                 455                 460                 465

 Asp Thr Arg Gly Pro Val Pro Gly Pro Arg Gly Pro Ile Pro Ser
                 470                 475                 480

 Gly Met Gln Gly Pro Ser Pro Ile Asn Met Gly Ala Val Val Pro
                 485                 490                 495

 Gln Gly Ser Arg Gln Val Pro Val Met Gln Gly Thr Gly Met Gln
                 500                 505                 510

 Gly Ala Ser Ile Gln Gly Gly Ser Gln Pro Gly Gly Phe Ser Pro
                 515                 520                 525

 Gly Gln Asn Gln Val Thr Pro Gln Asp His Glu Lys Ala Ala Leu
                 530                 535                 540

 Ile Met Gln Val Leu Gln Leu Thr Ala Asp Gln Ile Ala Met Leu
                 545                 550                 555

 Pro Pro Glu Gln Arg Gln Ser Ile Leu Ile Leu Lys Glu Gln Ile
                 560                 565                 570

 Gln Lys Ser Thr Gly Ala Pro
                 575

<210> 1141
<211> 3091
<212> DNA
<213> Homo sapien

<400> 1141
 gggagaccca agcttctaga gatccctcga cctcgagatc cattgtgctc 50

 taaagagcgg accccagcct ctgccaggtt cggtccgcca tcctcgtccc 100

 gtcctccgcc ggcccctgcc ccgcgcccag ggatcctcca gctcctttcg 150

 cccgcgccct ccgttcgctc cggacaccat ggacaagttt tggtggcacg 200

 cagcctgggg actctgcctc gtgccgctga gcctggcgca gatcgatttg 250

 aatataacct gccgctttgc aggtgtattc cacgtggaga aaaatggtcg 300

 ctacagcatc tctcggacgg aggccgctga cctctgcaag gctttcaata 350

 gcaccttgcc cacaatggcc cagatggaga aagctctgag catcggattt 400

 gagacctgca ggtatgggtt catagaaggg catgtggtga ttccccggat 450

 ccaccccaac tccatctgtg cagcaaacaa cacaggggtg tacatcctca 500

 catacaacac ctcccagtat gacacatatt gcttcaatgc ttcagctcca 550

 cctgaagaag attgtacatc agtcacagac ctgcccaatg cctttgatgg 600

 accaattacc ataactattg ttaaccgtga tggcacccgc tatgtccaga 650

 aaggagaata cagaacgaat cctgaagaca tctaccccag caaccctact 700

 gatgatgacg tgagcagcgg ctcctccagt gaaaggagca gcacttcagg 750

 aggttacatc ttttacacct tttctactgt acaccccatc ccagacgaag 800

 acagtccctg gatcaccgac agcacagaca gaatccctgc taccactttg 850

 atgagcacta gtgctacagc aactgagaca gcaaccaaga ggcaagaagc 900

 ctgggattgg ttttcatggt tgtttctacc atcagagtca aagaatcatc 950

 ttcacacaac aacacaaatg gctggtacgt cttcaaatac catctcagca 1000

 ggctgggagc caaatgaaga aaatgaagat gaaagagaca gacacctcag 1050

 tttttctgga tcaggcattg atgatgatga agattttatc tccagcacca 1100

 tttcaaccac accacgggcc tttgaccaca caaaacagaa ccaggactgg 1150

 acccagtgga acccaagcca ttcaaatccg gaagtgctac ttcagacaac 1200

 cacaaggatg actgatgtag acagaaatgg caccactgct tatgaaggaa 1250

 actggaaccc agaagcacac cctcccctca ttcaccatga gcatcatgag 1300

 gaagaagaga ccccacattc tacaagcaca atccaggcaa ctcctagtag 1350

 tacaacggaa gaaacagcta cccagaagga acagtggttt ggcaacagat 1400

 ggcatgaggg atatcgccaa acacccagag aagactccca ttcgacaaca 1450

 gggacagctg cagcctcagc tcataccagc catccaatgc aaggaaggac 1500

 aacaccaagc ccagaggaca gttcctggac tgatttcttc aacccaatct 1550

 cacaccccat gggacgaggt catcaagcag gaagaaggat ggatatggac 1600

 tccagtcata gtacaacgct tcagcctact gcaaatccaa acacaggttt 1650

 ggtggaaaat ttggacagga caggacctct ttcaatgaca acgcagcaga 1700

 gtaattctca gagcttctct acatcacatg aaggcttgga agaagataaa 1750

 gaccatccaa caacttctac tctgacatca agcaatagga atgatgtcac 1800

 aggtggaaga agagacccaa atcattctga aggctcaact actttactgg 1850

 aaggttatac ctctcattac ccacacacga aggaaagcag gaccttcatc 1900

 ccagtgacct cagctaagac tgggtccttt ggagttactg cagttactgt 1950

 tggagattcc aactctaatg tcaatcgttc cttatcagga gaccaagaca 2000

 cattccaccc cagtgggggg tcccatacca ctcatggatc tgaatcagat 2050

 ggacactcac atgggagtca agaaggtgga gcaaacacaa cctctggtcc 2100

 tataaggaca ccccaaattc cagaatggct gatcatcttg gcatccctct 2150

 tggccttggc tttgattctt gcagtttgca ttgcagtcaa cagtcgaaga 2200

 aggtgtgggc agaagaaaaa gctagtgatc aacagtggca atggagctgt 2250

 ggaggacaga aagccaagtg gactcaacgg agaggccagc aagtctcagg 2300

 aaatggtgca tttggtgaac aaggagtcgt cagaaactcc agaccagttt 2350

 atgacagctg atgagacaag gaacctgcag aatgtggaca tgaagattgg 2400

 ggtgtaacac ctacaccatt atcttggaaa gaaacaaccg ttggaaacat 2450

 aaccattaca gggagctggg acacttaaca gatgcaatgt gctactgatt 2500

 gtttcattgc gaatcttttt tagcataaaa ttttctactc tttttgtttt 2550

 ttgtgttttg ttctttaaag tcaggtccaa tttgtaaaaa cagcattgct 2600

 ttgtaaatta gggcccaatt aataatcagc aagaatttga tcgttcagtt 2650

 ccacttggag gccttcatcc tcgggtgtgc tatggatggc ttctaacaaa 2700

 aactacacat atgtattcct gatcgccaac ctttccccca ccagctaagg 2750

 acatttccca gggttaatag ggcctggtcc ctgggaggaa atttgaatgg 2800

 gtccattttg cccttccata gcctaatccc tgggcattgc tttccactga 2850

 ggttggggtg tactagttac acatcttcaa cagaccccct ctagaaattt 2900

 ttcagatgct tctgggagac accaaagggt gaagctattt atctgtagta 2950

 aactatttat ctgtgttttt gaaatattaa accctggatc agtcctttga 3000

 tcagtataat tttttaaagt tactttgtca gaggcacaaa agggtttaaa 3050

 ctgattcata ataaatatct gtacttcttc gatcttcaaa a 3091

<210> 1142
<211> 742
<212> PRT
<213> Homo sapien

<400> 1142
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val
   1               5                  10                  15

 Pro Leu Ser Leu Ala Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe
                  20                  25                  30

 Ala Gly Val Phe His Val Glu Lys Asn Gly Arg Tyr Ser Ile Ser
                  35                  40                  45

 Arg Thr Glu Ala Ala Asp Leu Cys Lys Ala Phe Asn Ser Thr Leu
                  50                  55                  60

 Pro Thr Met Ala Gln Met Glu Lys Ala Leu Ser Ile Gly Phe Glu
                  65                  70                  75

 Thr Cys Arg Tyr Gly Phe Ile Glu Gly His Val Val Ile Pro Arg
                  80                  85                  90

 Ile His Pro Asn Ser Ile Cys Ala Ala Asn Asn Thr Gly Val Tyr
                  95                 100                 105

 Ile Leu Thr Tyr Asn Thr Ser Gln Tyr Asp Thr Tyr Cys Phe Asn
                 110                 115                 120

 Ala Ser Ala Pro Pro Glu Glu Asp Cys Thr Ser Val Thr Asp Leu
                 125                 130                 135

 Pro Asn Ala Phe Asp Gly Pro Ile Thr Ile Thr Ile Val Asn Arg
                 140                 145                 150

 Asp Gly Thr Arg Tyr Val Gln Lys Gly Glu Tyr Arg Thr Asn Pro
                 155                 160                 165

 Glu Asp Ile Tyr Pro Ser Asn Pro Thr Asp Asp Asp Val Ser Ser
                 170                 175                 180

 Gly Ser Ser Ser Glu Arg Ser Ser Thr Ser Gly Gly Tyr Ile Phe
                 185                 190                 195

 Tyr Thr Phe Ser Thr Val His Pro Ile Pro Asp Glu Asp Ser Pro
                 200                 205                 210

 Trp Ile Thr Asp Ser Thr Asp Arg Ile Pro Ala Thr Thr Leu Met
                 215                 220                 225

 Ser Thr Ser Ala Thr Ala Thr Glu Thr Ala Thr Lys Arg Gln Glu
                 230                 235                 240

 Ala Trp Asp Trp Phe Ser Trp Leu Phe Leu Pro Ser Glu Ser Lys
                 245                 250                 255

 Asn His Leu His Thr Thr Thr Gln Met Ala Gly Thr Ser Ser Asn
                 260                 265                 270

 Thr Ile Ser Ala Gly Trp Glu Pro Asn Glu Glu Asn Glu Asp Glu
                 275                 280                 285

 Arg Asp Arg His Leu Ser Phe Ser Gly Ser Gly Ile Asp Asp Asp
                 290                 295                 300

 Glu Asp Phe Ile Ser Ser Thr Ile Ser Thr Thr Pro Arg Ala Phe
                 305                 310                 315

 Asp His Thr Lys Gln Asn Gln Asp Trp Thr Gln Trp Asn Pro Ser
                 320                 325                 330

 His Ser Asn Pro Glu Val Leu Leu Gln Thr Thr Thr Arg Met Thr
                 335                 340                 345

 Asp Val Asp Arg Asn Gly Thr Thr Ala Tyr Glu Gly Asn Trp Asn
                 350                 355                 360

 Pro Glu Ala His Pro Pro Leu Ile His His Glu His His Glu Glu
                 365                 370                 375

 Glu Glu Thr Pro His Ser Thr Ser Thr Ile Gln Ala Thr Pro Ser
                 380                 385                 390

 Ser Thr Thr Glu Glu Thr Ala Thr Gln Lys Glu Gln Trp Phe Gly
                 395                 400                 405

 Asn Arg Trp His Glu Gly Tyr Arg Gln Thr Pro Arg Glu Asp Ser
                 410                 415                 420

 His Ser Thr Thr Gly Thr Ala Ala Ala Ser Ala His Thr Ser His
                 425                 430                 435

 Pro Met Gln Gly Arg Thr Thr Pro Ser Pro Glu Asp Ser Ser Trp
                 440                 445                 450

 Thr Asp Phe Phe Asn Pro Ile Ser His Pro Met Gly Arg Gly His
                 455                 460                 465

 Gln Ala Gly Arg Arg Met Asp Met Asp Ser Ser His Ser Thr Thr
                 470                 475                 480

 Leu Gln Pro Thr Ala Asn Pro Asn Thr Gly Leu Val Glu Asn Leu
                 485                 490                 495

 Asp Arg Thr Gly Pro Leu Ser Met Thr Thr Gln Gln Ser Asn Ser
                 500                 505                 510

 Gln Ser Phe Ser Thr Ser His Glu Gly Leu Glu Glu Asp Lys Asp
                 515                 520                 525

 His Pro Thr Thr Ser Thr Leu Thr Ser Ser Asn Arg Asn Asp Val
                 530                 535                 540

 Thr Gly Gly Arg Arg Asp Pro Asn His Ser Glu Gly Ser Thr Thr
                 545                 550                 555

 Leu Leu Glu Gly Tyr Thr Ser His Tyr Pro His Thr Lys Glu Ser
                 560                 565                 570

 Arg Thr Phe Ile Pro Val Thr Ser Ala Lys Thr Gly Ser Phe Gly
                 575                 580                 585

 Val Thr Ala Val Thr Val Gly Asp Ser Asn Ser Asn Val Asn Arg
                 590                 595                 600

 Ser Leu Ser Gly Asp Gln Asp Thr Phe His Pro Ser Gly Gly Ser
                 605                 610                 615

 His Thr Thr His Gly Ser Glu Ser Asp Gly His Ser His Gly Ser
                 620                 625                 630

 Gln Glu Gly Gly Ala Asn Thr Thr Ser Gly Pro Ile Arg Thr Pro
                 635                 640                 645

 Gln Ile Pro Glu Trp Leu Ile Ile Leu Ala Ser Leu Leu Ala Leu
                 650                 655                 660

 Ala Leu Ile Leu Ala Val Cys Ile Ala Val Asn Ser Arg Arg Arg
                 665                 670                 675

 Cys Gly Gln Lys Lys Lys Leu Val Ile Asn Ser Gly Asn Gly Ala
                 680                 685                 690

 Val Glu Asp Arg Lys Pro Ser Gly Leu Asn Gly Glu Ala Ser Lys
                 695                 700                 705

 Ser Gln Glu Met Val His Leu Val Asn Lys Glu Ser Ser Glu Thr
                 710                 715                 720

 Pro Asp Gln Phe Met Thr Ala Asp Glu Thr Arg Asn Leu Gln Asn
                 725                 730                 735

 Val Asp Met Lys Ile Gly Val
                 740

<210> 1143
<211> 3091
<212> DNA
<213> Homo sapien

<400> 1143
 gggagaccca agcttctaga gatccctcga cctcgagatc cattgtgctc 50

 taaagagcgg accccagcct ctgccaggtt cggtccgcca tcctcgtccc 100

 gtcctccgcc ggcccctgcc ccgcgcccag ggatcctcca gctcctttcg 150

 cccgcgccct ccgttcgctc cggacaccat ggacaagttt tggtggcacg 200

 cagcctgggg actctgcctc gtgccgctga gcctggcgca gatcgatttg 250

 aatataacct gccgctttgc aggtgtattc cacgtggaga aaaatggtcg 300

 ctacagcatc tctcggacgg aggccgctga cctctgcaag gctttcaata 350

 gcaccttgcc cacaatggcc cagatggaga aagctctgag catcggattt 400

 gagacctgca ggtatgggtt catagaaggg catgtggtga ttccccggat 450

 ccaccccaac tccatctgtg cagcaaacaa cacaggggtg tacatcctca 500

 catacaacac ctcccagtat gacacatatt gcttcaatgc ttcagctcca 550

 cctgaagaag attgtacatc agtcacagac ctgcccaatg cctttgatgg 600

 accaattacc ataactattg ttaaccgtga tggcacccgc tatgtccaga 650

 aaggagaata cagaacgaat cctgaagaca tctaccccag caaccctact 700

 gatgatgacg tgagcagcgg ctcctccagt gaaaggagca gcacttcagg 750

 aggttacatc ttttacacct tttctactgt acaccccatc ccagacgaag 800

 acagtccctg gatcaccgac agcacagaca gaatccctgc taccactttg 850

 atgagcacta gtgctacagc aactgagaca gcaaccaaga ggcaagaagc 900

 ctgggattgg ttttcatggt tgtttctacc atcagagtca aagaatcatc 950

 ttcacacaac aacacaaatg gctggtacgt cttcaaatac catctcagca 1000

 ggctgggagc caaatgaaga aaatgaagat gaaagagaca gacacctcag 1050

 tttttctgga tcaggcattg atgatgatga agattttatc tccagcacca 1100

 tttcaaccac accacgggcc tttgaccaca caaaacagaa ccaggactgg 1150

 acccagtgga acccaagcca ttcaaatccg gaagtgctac ttcagacaac 1200

 cacaaggatg actgatgtag acagaaatgg caccactgct tatgaaggaa 1250

 actggaaccc agaagcacac cctcccctca ttcaccatga gcatcatgag 1300

 gaagaagaga ccccacattc tacaagcaca atccaggcaa ctcctagtag 1350

 tacaacggaa gaaacagcta cccagaagga acagtggttt ggcaacagat 1400

 ggcatgaggg atatcgccaa acacccagag aagactccca ttcgacaaca 1450

 gggacagctg cagcctcagc tcataccagc catccaatgc aaggaaggac 1500

 aacaccaagc ccagaggaca gttcctggac tgatttcttc aacccaatct 1550

 cacaccccat gggacgaggt catcaagcag gaagaaggat ggatatggac 1600

 tccagtcata gtacaacgct tcagcctact gcaaatccaa acacaggttt 1650

 ggtggaaaat ttggacagga caggacctct ttcaatgaca acgcagcaga 1700

 gtaattctca gagcttctct acatcacatg aaggcttgga agaagataaa 1750

 gaccatccaa caacttctac tctgacatca agcaatagga atgatgtcac 1800

 aggtggaaga agagacccaa atcattctga aggctcaact actttactgg 1850

 aaggttatac ctctcattac ccacacacga aggaaagcag gaccttcatc 1900

 ccagtgacct cagctaagac tgggtccttt ggagttactg cagttactgt 1950

 tggagattcc aactctaatg tcaatcgttc cttatcagga gaccaagaca 2000

 cattccaccc cagtgggggg tcccatacca ctcatggatc tgaatcagat 2050

 ggacactcac atgggagtca agaaggtgga gcaaacacaa cctctggtcc 2100

 tataaggaca ccccaaattc cagaatggct gatcatcttg gcatccctct 2150

 tggccttggc tttgattctt gcagtttgca ttgcagtcaa cagtcgaaga 2200

 aggtgtgggc agaagaaaaa gctagtgatc aacagtggca atggagctgt 2250

 ggaggacaga aagccaagtg gactcaacgg agaggccagc aagtctcagg 2300

 aaatggtgca tttggtgaac aaggagtcgt cagaaactcc agaccagttt 2350

 atgacagctg atgagacaag gaacctgcag aatgtggaca tgaagattgg 2400

 ggtgtaacac ctacaccatt atcttggaaa gaaacaaccg ttggaaacat 2450

 aaccattaca gggagctggg acacttaaca gatgcaatgt gctactgatt 2500

 gtttcattgc gaatcttttt tagcataaaa ttttctactc tttttgtttt 2550

 ttgtgttttg ttctttaaag tcaggtccaa tttgtaaaaa cagcattgct 2600

 ttgtaaatta gggcccaatt aataatcagc aagaatttga tcgttcagtt 2650

 ccacttggag gccttcatcc tcgggtgtgc tatggatggc ttctaacaaa 2700

 aactacacat atgtattcct gatcgccaac ctttccccca ccagctaagg 2750

 acatttccca gggttaatag ggcctggtcc ctgggaggaa atttgaatgg 2800

 gtccattttg cccttccata gcctaatccc tgggcattgc tttccactga 2850

 ggttggggtg tactagttac acatcttcaa cagaccccct ctagaaattt 2900

 ttcagatgct tctgggagac accaaagggt gaagctattt atctgtagta 2950

 aactatttat ctgtgttttt gaaatattaa accctggatc agtcctttga 3000

 tcagtataat tttttaaagt tactttgtca gaggcacaaa agggtttaaa 3050

 ctgattcata ataaatatct gtacttcttc gatcttcaaa a 3091

<210> 1144
<211> 742
<212> PRT
<213> Homo sapien

<400> 1144
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val
   1               5                  10                  15

 Pro Leu Ser Leu Ala Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe
                  20                  25                  30

 Ala Gly Val Phe His Val Glu Lys Asn Gly Arg Tyr Ser Ile Ser
                  35                  40                  45

 Arg Thr Glu Ala Ala Asp Leu Cys Lys Ala Phe Asn Ser Thr Leu
                  50                  55                  60

 Pro Thr Met Ala Gln Met Glu Lys Ala Leu Ser Ile Gly Phe Glu
                  65                  70                  75

 Thr Cys Arg Tyr Gly Phe Ile Glu Gly His Val Val Ile Pro Arg
                  80                  85                  90

 Ile His Pro Asn Ser Ile Cys Ala Ala Asn Asn Thr Gly Val Tyr
                  95                 100                 105

 Ile Leu Thr Tyr Asn Thr Ser Gln Tyr Asp Thr Tyr Cys Phe Asn
                 110                 115                 120

 Ala Ser Ala Pro Pro Glu Glu Asp Cys Thr Ser Val Thr Asp Leu
                 125                 130                 135

 Pro Asn Ala Phe Asp Gly Pro Ile Thr Ile Thr Ile Val Asn Arg
                 140                 145                 150

 Asp Gly Thr Arg Tyr Val Gln Lys Gly Glu Tyr Arg Thr Asn Pro
                 155                 160                 165

 Glu Asp Ile Tyr Pro Ser Asn Pro Thr Asp Asp Asp Val Ser Ser
                 170                 175                 180

 Gly Ser Ser Ser Glu Arg Ser Ser Thr Ser Gly Gly Tyr Ile Phe
                 185                 190                 195

 Tyr Thr Phe Ser Thr Val His Pro Ile Pro Asp Glu Asp Ser Pro
                 200                 205                 210

 Trp Ile Thr Asp Ser Thr Asp Arg Ile Pro Ala Thr Thr Leu Met
                 215                 220                 225

 Ser Thr Ser Ala Thr Ala Thr Glu Thr Ala Thr Lys Arg Gln Glu
                 230                 235                 240

 Ala Trp Asp Trp Phe Ser Trp Leu Phe Leu Pro Ser Glu Ser Lys
                 245                 250                 255

 Asn His Leu His Thr Thr Thr Gln Met Ala Gly Thr Ser Ser Asn
                 260                 265                 270

 Thr Ile Ser Ala Gly Trp Glu Pro Asn Glu Glu Asn Glu Asp Glu
                 275                 280                 285

 Arg Asp Arg His Leu Ser Phe Ser Gly Ser Gly Ile Asp Asp Asp
                 290                 295                 300

 Glu Asp Phe Ile Ser Ser Thr Ile Ser Thr Thr Pro Arg Ala Phe
                 305                 310                 315

 Asp His Thr Lys Gln Asn Gln Asp Trp Thr Gln Trp Asn Pro Ser
                 320                 325                 330

 His Ser Asn Pro Glu Val Leu Leu Gln Thr Thr Thr Arg Met Thr
                 335                 340                 345

 Asp Val Asp Arg Asn Gly Thr Thr Ala Tyr Glu Gly Asn Trp Asn
                 350                 355                 360

 Pro Glu Ala His Pro Pro Leu Ile His His Glu His His Glu Glu
                 365                 370                 375

 Glu Glu Thr Pro His Ser Thr Ser Thr Ile Gln Ala Thr Pro Ser
                 380                 385                 390

 Ser Thr Thr Glu Glu Thr Ala Thr Gln Lys Glu Gln Trp Phe Gly
                 395                 400                 405

 Asn Arg Trp His Glu Gly Tyr Arg Gln Thr Pro Arg Glu Asp Ser
                 410                 415                 420

 His Ser Thr Thr Gly Thr Ala Ala Ala Ser Ala His Thr Ser His
                 425                 430                 435

 Pro Met Gln Gly Arg Thr Thr Pro Ser Pro Glu Asp Ser Ser Trp
                 440                 445                 450

 Thr Asp Phe Phe Asn Pro Ile Ser His Pro Met Gly Arg Gly His
                 455                 460                 465

 Gln Ala Gly Arg Arg Met Asp Met Asp Ser Ser His Ser Thr Thr
                 470                 475                 480

 Leu Gln Pro Thr Ala Asn Pro Asn Thr Gly Leu Val Glu Asn Leu
                 485                 490                 495

 Asp Arg Thr Gly Pro Leu Ser Met Thr Thr Gln Gln Ser Asn Ser
                 500                 505                 510

 Gln Ser Phe Ser Thr Ser His Glu Gly Leu Glu Glu Asp Lys Asp
                 515                 520                 525

 His Pro Thr Thr Ser Thr Leu Thr Ser Ser Asn Arg Asn Asp Val
                 530                 535                 540

 Thr Gly Gly Arg Arg Asp Pro Asn His Ser Glu Gly Ser Thr Thr
                 545                 550                 555

 Leu Leu Glu Gly Tyr Thr Ser His Tyr Pro His Thr Lys Glu Ser
                 560                 565                 570

 Arg Thr Phe Ile Pro Val Thr Ser Ala Lys Thr Gly Ser Phe Gly
                 575                 580                 585

 Val Thr Ala Val Thr Val Gly Asp Ser Asn Ser Asn Val Asn Arg
                 590                 595                 600

 Ser Leu Ser Gly Asp Gln Asp Thr Phe His Pro Ser Gly Gly Ser
                 605                 610                 615

 His Thr Thr His Gly Ser Glu Ser Asp Gly His Ser His Gly Ser
                 620                 625                 630

 Gln Glu Gly Gly Ala Asn Thr Thr Ser Gly Pro Ile Arg Thr Pro
                 635                 640                 645

 Gln Ile Pro Glu Trp Leu Ile Ile Leu Ala Ser Leu Leu Ala Leu
                 650                 655                 660

 Ala Leu Ile Leu Ala Val Cys Ile Ala Val Asn Ser Arg Arg Arg
                 665                 670                 675

 Cys Gly Gln Lys Lys Lys Leu Val Ile Asn Ser Gly Asn Gly Ala
                 680                 685                 690

 Val Glu Asp Arg Lys Pro Ser Gly Leu Asn Gly Glu Ala Ser Lys
                 695                 700                 705

 Ser Gln Glu Met Val His Leu Val Asn Lys Glu Ser Ser Glu Thr
                 710                 715                 720

 Pro Asp Gln Phe Met Thr Ala Asp Glu Thr Arg Asn Leu Gln Asn
                 725                 730                 735

 Val Asp Met Lys Ile Gly Val
                 740

<210> 1145
<211> 7706
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2113-2135
<223> Unknown base

<400> 1145
 gaattcggca cgaggtggtg gccgcgcacc cggccgcggc tgattcattc 50

 acttcaagtg ccgtgcagaa ggctcggcag gcggggcggg cgtggggccg 100

 cggctccggg ttggggaccg aggagatccg gctgtggacc agacgctcct 150

 ctgcggggcg ggcacccaag cgcgctcgcc accccctcgc catccgctag 200

 agccgggctc ctggactggg actcgggccc gccgcacagt tgaaaagtcg 250

 catagtggtt tttccgctcg cgtcgctgtg tgaaagttgg ctcgccgctc 300

 tttgcacgcc ctccctggag gccgacccga gacgccaagc tggagagacc 350

 gtgcctcccc gaggccggcc gccccgcgag cacagcctcc gcccccgttg 400

 cactgccggg ctgggcaata tgaaggagca gccctcatgt gccggcaccg 450

 ggcatccgag catggcggga ggaggcctac cagaaactgg ccagcgagac 500

 cctggaggag ctggactggt gtctggacca gctagagacc ctacagacca 550

 ggcactccgt cagtgagatg gcctccaaca agtttaaaag gatgcttaat 600

 cgggagctca cccatctctc tgaaatgagt cggtctggaa atcaagtgtc 650

 agagtttata tcaaacacat tcttagataa gcaacatgaa gtggaaattc 700

 cttctccaac tcagaaggaa aaggagaaaa agaaaagacc aatgtctcag 750

 atcagtggag tcaagaaatt gatgcacagc tctagtctga ctaattcaag 800

 tatcccaagg tttggagtta aaactgaaca agaagatgtc cttgccaagg 850

 aactagaaga tgtgaacaaa tggggtcttc atgttttcag aatagcagag 900

 ttgtctggta accggccctt gactgttatc atgcacacca tttttcagga 950

 acgggattta ttaaaaacat ttaaaattcc agtagatact ttaattacat 1000

 atcttatgac tctcgaagac cattaccatg ctgatgtggc ctatcacaac 1050

 aatatccatg ctgcagatgt tgtccagtct actcatgtgc tattatctac 1100

 acctgctttg gaggctgtgt ttacagattt ggagattctt gcagcaattt 1150

 ttgccagtgc aatacatgat gtagatcatc ctggtgtgtc caatcaattt 1200

 ctgatcaata caaactctga acttgccttg atgtacaatg attcctcagt 1250

 cttagagaac catcatttgg ctgtgggctt taaattgctt caggaagaaa 1300

 actgtgacat tttccagaat ttgaccaaaa aacaaagaca atctttaagg 1350

 aaaatggtca ttgacatcgt acttgcaaca gatatgtcaa aacacatgaa 1400

 tctactggct gatttgaaga ctatggttga aactaagaaa gtgacaagct 1450

 ctggagttct tcttcttgat aattattccg ataggattca ggttcttcag 1500

 aatatggtgc actgtgcaga tctgagcaac ccaacaaagc ctctccagct 1550

 gtaccgccag tggacggacc ggataatgga ggagttcttc cgccaaggag 1600

 accgagagag ggaacgtggc atggagataa gccccatgtg tgacaagcac 1650

 aatgcttccg tggaaaaatc acaggtgggc ttcatagact atattgttca 1700

 tcccctctgg gagacatggg cagacctcgt ccaccctgac gcccaggata 1750

 ttttggacac tttggaggac aatcgtgaat ggtaccagag cacaatccct 1800

 cagagcccct ctcctgcacc tgatgaccca gaggagggcc ggcagggtca 1850

 aactgagaaa ttccagtttg aactaacttt agaggaagat ggtgagtcag 1900

 acacggaaaa ggacagtggc agtcaagtgg aagaagacac tagctgcagt 1950

 gactccaaga ctctttgtac tcaagactca gagtctactg aaattcccct 2000

 tgatgaacag gttgaagagg aggcagtagg ggaagaagag gaaagccagc 2050

 ctgaagcctg tgtcatagat gatcgttctc ctgacacgta acagtgcaaa 2100

 aactttcatg ccnnnnnnnn nnnnnnnnnn nnnnnttgtt tccaaagtgc 2150

 atgtcacatg ccacaaccac ggtcacacct cactgtcatc tgccaggacg 2200

 tttgttgaac aaaactgacc ttgactactc agtccagcgc tcaggaatat 2250

 cgtaaccagt tttttcacct ccatgttcat ccgagcaagg tggacatctt 2300

 cacgaacagc gtttttaaca agatttcagc ttggtagagc tgacaaagca 2350

 gataaaatct actccaaatt attttcaaga gagtgtgact catcaggcag 2400

 cccaaaagtt tattggactt ggggtttcta ttccttttta tttgtttgca 2450

 atattttcag aagaaaggca ttgcacagag tgaacttaat ggacgaagca 2500

 acaaatatgt caagaacagg acatagcacg aatctgttac cagtaggagg 2550

 aggatgagcc acagaaattg cataattttc taatttcaag tcttcctgat 2600

 acatgactga atagtgtggt tcagtgagct gcactgacct ctacattttg 2650

 tatgatatgt aaaacagatt ttttgtagag cttactttta ttattaaatg 2700

 tattgaggta ttatatttaa aaaaaactat gttcagaact tcatctgcca 2750

 ctggttattt ttttctaagg agtaacttgc aagttttcag tacaaatctg 2800

 tgctacactg gataaaaatc taatttatga attttacttg caccttatag 2850

 ttcatagcaa ttaactgatt tgtagtgatt cattgttgtt ttatatacca 2900

 atgacttcca tattttaaaa gagaaaaaca actttatgtg caggaaaccc 2950

 ttttgtaagt ctttattatt tacttgcatt tgtttcactc tttccagata 3000

 agcagagtgc tcttcaccag gtttttcttc atgtgcaaag tgactattgt 3050

 tctataatac ttttatgtgt gttatatcaa atgtgtctta agcttcatgc 3100

 aaactcagtc atcagttcgt gtgtctgaag caagtgggag atatataaat 3150

 acccagtagc taaaatggtc agtctttttt agatgttttc ctacttagta 3200

 tctcctaata acgtttgctg tgtcactaga tgttcatttc acaagtgcat 3250

 gtctttctaa taatccacac atttcatgct ctaataatcc acacatttca 3300

 tgctcatttt tattgttttt acagccagtt atagtaagaa aaaggttttt 3350

 ccccttgtgc tgctttataa tttagcgtgt gtctgaacct tatccatgtt 3400

 tgctagatga ggtcttgtca aatatatcac taccattgtc accggtgaaa 3450

 agaaacaggt agttaagtta gggttaacat tcatttcaac cacgaggttg 3500

 tatatcatga ctagctttta ctcttggttt acagagaaaa gttaaacagc 3550

 caactaggca gtttttaaga atattaacaa tatattaaca aacaccaata 3600

 caactaatcc tatttggttt taatgatttc accatgggat taagaactat 3650

 atcaggaaca tccctgagaa acggttttaa gtgtagcaac tactcttcct 3700

 taatggacag ccacataaca tgtaggaagt cctttatcac ttatcctcga 3750

 tccataagca tatcttgcag aggggaacta cttctttaaa cacatggagg 3800

 gaaagaagat gatgccactg gcaccagagg gttagtactg tgatgcatcc 3850

 taaaatattt attatattgg taaaaattct ggttaaataa aaaattagag 3900

 atcactcttg gctgatttca gcaccaggaa ctgtattaca gttttagaga 3950

 ttaattccta gtgtttacct gattatagca gttggcatca tggggcattt 4000

 aattctgact ttatccccac gtcagcctta ataaagtctt ctttaccttc 4050

 tctatgaaga ctttaaagcc caaataatca tttttcacat tgatattcaa 4100

 gaattgagat agatagaagc caaagtgggt atctgacaag tggaaaatca 4150

 aacgtttaag aagaattaca actctgaaaa gcatttatat gtggaacttc 4200

 tcaaggagcc tcctggggac tggaaagtaa gtcatcagcc aggcaaatga 4250

 ctcatgctga agagagtccc catttcagtc ccctgagatc tagctgatgc 4300

 ttagatcctt tgaaataaaa attatgtctt tataactctg atcttttaca 4350

 taaagcagaa gaggaatcaa ctagttaatt gcaaggtttc tactctgttt 4400

 cctctgtaaa gatcagatgg taatctttca aataagaaaa aaataaagac 4450

 gtatgtttga ccaagtagtt tcacaagaat atttgggaac ttgtttcttt 4500

 taattttatt tgtccctgag tgaagtctag aaagaaaggt aaagagtcta 4550

 gagtttattc ctctttccaa aacattctca ttcctctcct ccctactctt 4600

 agtatttccc ccacagagtg cctagaatct taataatgaa taaaataaaa 4650

 agcagcaata tgtcattaac aaatccagac ctgaaagggt aaagggttta 4700

 taactgcact aataaagaga ggctcttttt ttttcttcca gtttgttggt 4750

 ttttaatggt accgtgttgt aaagataccc actaatggac aatcaaattg 4800

 cagaaaaggc tcaatatcca agagacaggg actaatgcac tgtacaatcg 4850

 gcttatcctt gcccttctct cttgccaaag tgtgcttcag aaatatatac 4900

 tgctttaaaa aagaataaaa gaatatcctt ttacaagtgg ctttacattt 4950

 cctaaaatgc cataagaaaa tgcaatatct gggtactgta tggggaaaaa 5000

 aatgtccaag tttgtataaa accagtgcat ttcagcttgc aagttactga 5050

 acacaataat gctgttttaa ttttgtttta tatcagttaa aattcacaat 5100

 aatgtagata gaacaaatta cagacaagga aagaaaaaac ttgaatgaaa 5150

 tggattttac agaaagcttt atgataattt ttgaatgcat tatttatttt 5200

 ttgtgccatg catttttttt ctcaccaaat gaccttacct gtaatacagt 5250

 cttgtttgtc tgtttacaac catgtattta ttgcaatgta catactgtaa 5300

 tgttaattgt aaattatctg ttcttattaa aacatcatcc catgatggga 5350

 tggtgttgat atatttggaa actcttggtg agagaatgaa tggtgtgtat 5400

 acatactctg tacatttttc ttttctcctg taatatagtc ttgtcacctt 5450

 agagcttgtt tatggaagat tcaagaaaac tataaaatac ttaaagatat 5500

 ataaatttaa aaaaacatag ctgcaggtct ttggtcccag ggctgtgcct 5550

 taactttaac caatattttc ttctgttttg ctgcatttga aaggtaacag 5600

 tggagctagg gctgggcatt ttacatccag gcttttaatt gattagaatt 5650

 ctgccaatag gtggatttta caaaaccaca gacaacctct gaaagattct 5700

 gagacccttt tgagacagaa gctcttaagt acttcttgcc agggagcagc 5750

 actgcatgtg tgatggttgt ttgccatctg ttgatcagga actacttcag 5800

 ctacttgcat ttgattattt cctttttttc tttttttata actcggaaac 5850

 acaactgggg aaatatattc tttcccagtg attataaaca atctttttct 5900

 tttttttaag tccttttggc ttctagagct cataggaaaa tggacttgat 5950

 ttgaaattgg agccagagtt tactcgtgtt ggttatctat tcatcagctt 6000

 cctgacatgt taagagaata cattaaagag aaaatactgt tttttaatcc 6050

 taaaattttt cttccactaa gataaaccaa atgtgcttac atatatgtaa 6100

 acccatctat ttaaacgcaa aggtgggttg atgtcagttt acatagcaga 6150

 aagcattcac tatcctctaa gatttgtttc tgcaaaactt tcattgcttt 6200

 agaattttaa aatttcacct tgtacaatgg ccagccccta aagcaggaaa 6250

 catttataat ggattatatg gaaacatcct cccagtactt gcccagccct 6300

 tgaatcatgt ggcttttcag tgaaaggaaa gattcttttt ctaggaaaaa 6350

 tgagcctatt ttattttatt ttattttatt ttttgacaca aactgtagat 6400

 tttagcagcc ctggcccaaa ggaatttgat tacttttgtt ttaaacagta 6450

 caaaggggac actataatta caaaaacatc cttaactgat ttgagttgtt 6500

 tttatttctt tggatatatt ttcagagtgg taaattgtgt gtgagaatta 6550

 caaatgatta ttcttttagt ggtttcttag cctctcttac agcccacggg 6600

 gatagtactg tacatcaata ccttcatatg aaatttttat atgcaatgaa 6650

 aataaaagca tgggttgatt ctgcctattt atgactcaat cttttacaaa 6700

 taaaagatta ttcattttaa attatagttc aatcagcatg tctcttagga 6750

 tactgaacgt ggttgaaatg aaaggatagt gacatcataa gttagtactg 6800

 atattcataa ccaaataaag ccaacttgag taattttgct acattaaaaa 6850

 ttaccaaaat tacttagatg gcctataaga ttaacgcatg gtgttttcta 6900

 agcaagcttt gaaaggggcc ttccatactt acttaattga atattctggg 6950

 atattgaaaa ttattcagat acttgacaat tatttttggt tacctactcc 7000

 gcaaactaca aagttttaag gactcaacaa taagttaatg agacacagtg 7050

 tttgctttca tggagcttac agtctggagg ggacaaaggc ttaaacaata 7100

 ctcatataat tatatatgtg atcagtacaa tgaaggagct cagtggggta 7150

 aataagcagg aacctgaact tgatctgttc cggagggcca cagaaggctt 7200

 ccttgaggcc ttgagaaagt gatttgcatc tgagttctga aggattgtaa 7250

 gaggtaacta gggaaaaagt tgacaggaag aggaagggga tccagacaag 7300

 aaacatttgc aaagatcttg aggcataaat gagcttgaga catctggaga 7350

 aactgaggaa aagtgagaga gtaggcaggg cctggagccg cagagccatt 7400

 gctaaccatc ctgtgtgaga tatcccccat tctgtagctt tattctcata 7450

 accctgctca attttcttta taacacttct cacagattta tatacgtgtt 7500

 tgtttttgtt atctgtctct cccaccagac cacagctcca tgagagcaag 7550

 gtctttgctt accaatatat cactagcact taaaactatg cctggtacac 7600

 agtaggttct taatatgtgt tgaatatagc catcaaattg atattggata 7650

 taattcaatc tgataagata ttttgagata ttaaagagtt tttaacttga 7700

 tcccat 7706

<210> 1146
<211> 696
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2113-2135
<223> Unknown amino acid

<400> 1146
 Glu Phe Gly Thr Arg Trp Trp Pro Arg Thr Arg Pro Arg Leu Ile
   1               5                  10                  15

 His Ser Leu Gln Val Pro Cys Arg Arg Leu Gly Arg Arg Gly Gly
                  20                  25                  30

 Arg Gly Ala Ala Ala Pro Gly Trp Gly Pro Arg Arg Ser Gly Cys
                  35                  40                  45

 Gly Pro Asp Ala Pro Leu Arg Gly Gly His Pro Ser Ala Leu Ala
                  50                  55                  60

 Thr Pro Ser Pro Ser Ala Ser Arg Ala Pro Gly Leu Gly Leu Gly
                  65                  70                  75

 Pro Ala Ala Gln Leu Lys Ser Arg Ile Val Val Phe Pro Leu Ala
                  80                  85                  90

 Ser Leu Cys Glu Ser Trp Leu Ala Ala Leu Cys Thr Pro Ser Leu
                  95                 100                 105

 Glu Ala Asp Pro Arg Arg Gln Ala Gly Glu Thr Val Pro Pro Arg
                 110                 115                 120

 Gly Arg Pro Pro Arg Glu His Ser Leu Arg Pro Arg Cys Thr Ala
                 125                 130                 135

 Gly Leu Gly Asn Met Lys Arg Ser Ser Pro His Val Pro Ala Pro
                 140                 145                 150

 Gly Ile Arg Ala Trp Arg Glu Glu Ala Tyr Gln Lys Leu Ala Ser
                 155                 160                 165

 Glu Thr Leu Glu Glu Leu Asp Trp Cys Leu Asp Gln Leu Glu Thr
                 170                 175                 180

 Leu Gln Thr Arg His Ser Val Ser Glu Met Ala Ser Asn Lys Phe
                 185                 190                 195

 Lys Arg Met Leu Asn Arg Glu Leu Thr His Leu Ser Glu Met Ser
                 200                 205                 210

 Arg Ser Gly Asn Gln Val Ser Glu Phe Ile Ser Asn Thr Phe Leu
                 215                 220                 225

 Asp Lys Gln His Glu Val Glu Ile Pro Ser Pro Thr Gln Lys Glu
                 230                 235                 240

 Lys Glu Lys Lys Lys Arg Pro Met Ser Gln Ile Ser Gly Val Lys
                 245                 250                 255

 Lys Leu Met His Ser Ser Ser Leu Thr Asn Ser Ser Ile Pro Arg
                 260                 265                 270

 Phe Gly Val Lys Thr Glu Gln Glu Asp Val Leu Ala Lys Glu Leu
                 275                 280                 285

 Glu Asp Val Asn Lys Trp Gly Leu His Val Phe Arg Ile Ala Glu
                 290                 295                 300

 Leu Ser Gly Asn Arg Pro Leu Thr Val Ile Met His Thr Ile Phe
                 305                 310                 315

 Gln Glu Arg Asp Leu Leu Lys Thr Phe Lys Ile Pro Val Asp Thr
                 320                 325                 330

 Leu Ile Thr Tyr Leu Met Thr Leu Glu Asp His Tyr His Ala Asp
                 335                 340                 345

 Val Ala Tyr His Asn Asn Ile His Ala Ala Asp Val Val Gln Ser
                 350                 355                 360

 Thr His Val Leu Leu Ser Thr Pro Ala Leu Glu Ala Val Phe Thr
                 365                 370                 375

 Asp Leu Glu Ile Leu Ala Ala Ile Phe Ala Ser Ala Ile His Asp
                 380                 385                 390

 Val Asp His Pro Gly Val Ser Asn Gln Phe Leu Ile Asn Thr Asn
                 395                 400                 405

 Ser Glu Leu Ala Leu Met Tyr Asn Asp Ser Ser Val Leu Glu Asn
                 410                 415                 420

 His His Leu Ala Val Gly Phe Lys Leu Leu Gln Glu Glu Asn Cys
                 425                 430                 435

 Asp Ile Phe Gln Asn Leu Thr Lys Lys Gln Arg Gln Ser Leu Arg
                 440                 445                 450

 Lys Met Val Ile Asp Ile Val Leu Ala Thr Asp Met Ser Lys His
                 455                 460                 465

 Met Asn Leu Leu Ala Asp Leu Lys Thr Met Val Glu Thr Lys Lys
                 470                 475                 480

 Val Thr Ser Ser Gly Val Leu Leu Leu Asp Asn Tyr Ser Asp Arg
                 485                 490                 495

 Ile Gln Val Leu Gln Asn Met Val His Cys Ala Asp Leu Ser Asn
                 500                 505                 510

 Pro Thr Lys Pro Leu Gln Leu Tyr Arg Gln Trp Thr Asp Arg Ile
                 515                 520                 525

 Met Glu Glu Phe Phe Arg Gln Gly Asp Arg Glu Arg Glu Arg Gly
                 530                 535                 540

 Met Glu Ile Ser Pro Met Cys Asp Lys His Asn Ala Ser Val Glu
                 545                 550                 555

 Lys Ser Gln Val Gly Phe Ile Asp Tyr Ile Val His Pro Leu Trp
                 560                 565                 570

 Glu Thr Trp Ala Asp Leu Val His Pro Asp Ala Gln Asp Ile Leu
                 575                 580                 585

 Asp Thr Leu Glu Asp Asn Arg Glu Trp Tyr Gln Ser Thr Ile Pro
                 590                 595                 600

 Gln Ser Pro Ser Pro Ala Pro Asp Asp Pro Glu Glu Gly Arg Gln
                 605                 610                 615

 Gly Gln Thr Glu Lys Phe Gln Phe Glu Leu Thr Leu Glu Glu Asp
                 620                 625                 630

 Gly Glu Ser Asp Thr Glu Lys Asp Ser Gly Ser Gln Val Glu Glu
                 635                 640                 645

 Asp Thr Ser Cys Ser Asp Ser Lys Thr Leu Cys Thr Gln Asp Ser
                 650                 655                 660

 Glu Ser Thr Glu Ile Pro Leu Asp Glu Gln Val Glu Glu Glu Ala
                 665                 670                 675

 Val Gly Glu Glu Glu Glu Ser Gln Pro Glu Ala Cys Val Ile Asp
                 680                 685                 690

 Asp Arg Ser Pro Asp Thr
                 695

<210> 1147
<211> 1105
<212> DNA
<213> Homo sapien

<400> 1147
 gggcgggtag tcgaccgtgt ccgcgcgcct gggagacgct gcctcggccc 50

 ggacgcgccc gcgcccccgc ggctggaggg tggtcgccac tgggacactg 100

 tgaaccagga gtgagtcgga gctgccgcgc tgcccaggcc atggactgtg 150

 aggtcaacaa cggttccagc ctcagggatg agtgcatcac aaacctactg 200

 gtgtttggct tcctccaaag ctgttctgac aacagcttcc gcagagagct 250

 ggacgcactg ggccacgagc tgccagtgct ggctccccag tgggagggct 300

 acgatgagct gcagactgat ggcaaccgca gcagccactc ccgcttggga 350

 agaatagagg cagattctga aagtcaagaa gacatcatcc ggaatattgc 400

 caggcacctc gcccaggtcg gggacagcat ggaccgtagc atccctccgg 450

 gcctggtgaa cggcctggcc ctgcagctca ggaacaccag ccggtcggag 500

 gaggaccgga acagggacct ggccactgcc ctggagcagc tgctgcaggc 550

 ctaccctaga gacatggaga aggagaagac catgctggtg ctggccctgc 600

 tgctggccaa gaaggtggcc agtcacacgc cgtccttgct ccgtgatgtc 650

 tttcacacaa cagtgaattt tattaaccag aacctacgca cctacgtgag 700

 gagcttagcc agaaatggga tggactgaac ggacagttcc agaagtgtga 750

 ctggctaaag cttgatgtgg tcacagctgt atagctgctt ccagtgtaga 800

 cggagccctg gcatgtcaac agcgttccta gagaagacag gctggaagat 850

 agctgtgact tctattttaa agacaatgtt aaacttataa cccactttaa 900

 aatatctaca ttaatatact tgaatgaaaa tgtccattta cacgtatttg 950

 aatggccttc atatcatcca cacatgaatc tgcacatctg taaatctaca 1000

 cacggtgcct ttatttccac tgtgcaggtt cccacttaaa aattaaattg 1050

 gaaagcaggt ttcaaggaag tagaaacaaa atacaatttt tttggtaaaa 1100

 aaaaa 1105

<210> 1148
<211> 195
<212> PRT
<213> Homo sapien

<400> 1148
 Met Asp Cys Glu Val Asn Asn Gly Ser Ser Leu Arg Asp Glu Cys
   1               5                  10                  15

 Ile Thr Asn Leu Leu Val Phe Gly Phe Leu Gln Ser Cys Ser Asp
                  20                  25                  30

 Asn Ser Phe Arg Arg Glu Leu Asp Ala Leu Gly His Glu Leu Pro
                  35                  40                  45

 Val Leu Ala Pro Gln Trp Glu Gly Tyr Asp Glu Leu Gln Thr Asp
                  50                  55                  60

 Gly Asn Arg Ser Ser His Ser Arg Leu Gly Arg Ile Glu Ala Asp
                  65                  70                  75

 Ser Glu Ser Gln Glu Asp Ile Ile Arg Asn Ile Ala Arg His Leu
                  80                  85                  90

 Ala Gln Val Gly Asp Ser Met Asp Arg Ser Ile Pro Pro Gly Leu
                  95                 100                 105

 Val Asn Gly Leu Ala Leu Gln Leu Arg Asn Thr Ser Arg Ser Glu
                 110                 115                 120

 Glu Asp Arg Asn Arg Asp Leu Ala Thr Ala Leu Glu Gln Leu Leu
                 125                 130                 135

 Gln Ala Tyr Pro Arg Asp Met Glu Lys Glu Lys Thr Met Leu Val
                 140                 145                 150

 Leu Ala Leu Leu Leu Ala Lys Lys Val Ala Ser His Thr Pro Ser
                 155                 160                 165

 Leu Leu Arg Asp Val Phe His Thr Thr Val Asn Phe Ile Asn Gln
                 170                 175                 180

 Asn Leu Arg Thr Tyr Val Arg Ser Leu Ala Arg Asn Gly Met Asp
                 185                 190                 195

<210> 1149
<211> 4220
<212> DNA
<213> Homo sapien

<400> 1149
 acgttgcccg ggatgcggac aggttccgcc gcctccagcg ccccatcctg 50

 agccgattat ctgcaattat gaaatgaagt aactcaagat gagcaagtta 100

 aaagtgatac cagaaaaaag ccttaccaat aattctagga tcgtaggact 150

 cctggctcaa ctggagaaga tcaatgctga gccttcagaa tcagacactg 200

 cccgatatgt tacatcaaaa attcttcatc tggctcagag tcaagaaaaa 250

 acaaggagag aaatgacagc caaaggttct acaggaatgg aaattctgct 300

 gtcaacatta gagaacacaa aagatcttca aactacactt aatatcttaa 350

 gcattcttgt tgagctggtg tcagctggtg gaggtcgaag agtgagtttc 400

 ttagtcacca aaggtggttc acaaatattg ttgcagttac ttatgaatgc 450

 cagcaaagaa tctcccccac atgaggactt aatggtacag attcattcta 500

 ttcttgcaaa gattggacca aaagataaaa aatttggagt aaaggctaga 550

 attaatgggg ctctgaatat aaccctgaat ttggtcaagc agaatttgca 600

 gaatcatcgc ttggttctac cttgccttca gcttttacga gtatattctg 650

 ccaactctgt gaattcagta tccttaggga aaaatggagt tgtggaactg 700

 atgtttaaaa tcattggacc atttagtaag aagaattcca gtcttataaa 750

 ggttgcttta gacactcttg ctgcattgct aaaatcaaaa acaaatgcca 800

 ggagagctgt agacagagga tatgtccaag tgcttttaac aatttatgta 850

 gattggcacc gccatgataa ccggcataga aacatgctca ttcggaaagg 900

 aattttacgg agtttaaaaa gtgttacaaa catcaagttg ggaagaaaag 950

 catttattga tgccaatggg atgaaaattc tgtataatac ttcgcaattg 1000

 cctgttattc ctgtgactgg tcctgtggct cagctctaca gcttacctcc 1050

 tgaagtggat gacgtagtag atgaaagtga tgacaacgat gatattgatg 1100

 tagaagctga aaacgaaact gagaatgaag atgacctaga tcaaaatttt 1150

 aagaatgatg atattgaaac agatattaac aaactaaaac cccagcaaga 1200

 accgggacga acaatagaag atctaaaaat gtatgaacac cttttccctg 1250

 agcttgttga tgattttcag gactatgatt taatctccaa agaaccaaag 1300

 ccttttgtat ttgagggaaa agtacgtggt cctattgttg ttcctacggc 1350

 aggcgaggga acatctggga attctggcaa tttaagaaaa gttgtaatga 1400

 aggagaacat atcttctaaa ggagatgaag gtgaaaagaa gtctaccttt 1450

 atggatctag caaaagaaga tattaaagat aatgatagaa cattacaaca 1500

 gcagccaggt gatcaaaata gaactatttc atcagtccat ggtttaaaca 1550

 atgatattgt aaaggccttg gaccgaatta cattgcagaa tattccttct 1600

 caaacagccc caggttttac tgcagaaatg aagaaggact gcagtcttcc 1650

 tcttactgtc cttacctgtg ctaaagcatg tccacacatg gctacttgtg 1700

 gaaatgttct gtttgaggga agaacagttc agctagggaa gctttgctgc 1750

 actggagttg gaactgaaga tgatgaagat actgagtcaa attcatcggt 1800

 agaacaagca tcggttgaag tacctgatgg accaacactc catgacccag 1850

 acctctatat tgagattgtg aaaaatacga agtctgtccc agaatattca 1900

 gaggtggctt atcccgatta ttttggtcac attccgcctc cattcaaaga 1950

 gcctatttta gaaaggcctt atggtgtaca aaggacaaaa attgctcaag 2000

 atattgaaag gctaatacat cagagtgata tcatagatcg tgtggtatat 2050

 gacttggata acccaaatta caccattcca gaagagggag atattttgaa 2100

 atttaactcc aaatttgagt ctgggaatct gcgcaaagta attcaaatta 2150

 gaaaaaatga atatgatctt attctgaact cagacataaa cagcaatcat 2200

 tatcatcagt ggttttactt tgaagtcagt ggaatgcgac caggtgttgc 2250

 ttacaggttt aacatcatta actgtgaaaa gtccaacagt cagtttaatt 2300

 atggtatgca accactcatg tattcggttc aggaagcatt aaatgccaga 2350

 ccatggtgga ttcgtatggg gactgacatt tgttactata aaaatcattt 2400

 ctcaagaagt tcagttgctg caggtgggca aaagggaaaa tcctactata 2450

 caattacatt tactgtcaat tttccacata aagatgatgt ttgctacttt 2500

 gcttatcact atccatatac gtattcaact ttacagatgc atcttcaaaa 2550

 attggaatca gcacacaatc ctcagcaaat ctattttcgg aaagatgtgt 2600

 tatgtgaaac cctgtctgga aacagctgcc ccttggtgac tataacagca 2650

 atgccagagt ctaattatta tgaacatatc tgccatttca gaaatcgccc 2700

 ttacgttttc ttgtctgctc gggtacatcc tggagaaact aatgcaagtt 2750

 gggttatgaa aggaacgttg gaatatctca tgagcaataa ccccactgct 2800

 cagagcttac gagaatctta tatttttaaa attgtcccta tgttaaatcc 2850

 agatggtgtc atcaatggaa atcatcgctg ttctttaagt ggagaggatt 2900

 tgaataggca gtggcaaagt ccaagtccgg atttacatcc tacaatttac 2950

 catgctaagg ggctgttgca atacttggct gcagtgaagc gtttaccctt 3000

 ggtttattgt gattatcatg gccattcccg aaagaagaat gtatttatgt 3050

 atggttgcag catcaaagag acagtgtggc ataccaatga taatgcaact 3100

 tcatgtgatg ttgtggagga tacgggatac aggacattgc ctaagatact 3150

 gagccatatc gccccagcat tttgcatgag cagctgtagc ttcgtagtgg 3200

 aaaaatctaa agaatccaca gcacgtgttg tagtttggag ggaaatagga 3250

 gtacaaagaa gttataccat ggagagtact ttatgtggct gtgatcaggg 3300

 aaaatacaag ggtttacaga ttggtacccg agaactggaa gagatgggag 3350

 caaaattttg tgttggtctt ttacgtttga aaagactgac ctctccattg 3400

 gagtataatc tgccttccag cctgcttgac tttgaaaatg atttaattga 3450

 atcaagctgc aaagtaacta gccctaccac ttatgtcttg gatgaagatg 3500

 aacctcgatt ccttgaagaa gttgattaca gtgcagaaag taatgatgag 3550

 ttagatattg agttggctga aaatgtagga gattatgaac cttctgctca 3600

 agaagaagta ctttctgact ctgaattatc aagaacatac ctaccttgag 3650

 cccgctgcca tctcttgtta actgcaaaga ataaatgaaa tatcttggtt 3700

 tttatttccc aggaagcttg agagaaatga gtttatacag agctgactca 3750

 aaaagacaaa aagtaacttg ggccagtttg gtttcaagat aataaatgtg 3800

 ttattaatta atgataaaat tggcgcttgt tttattttcg atattcaatg 3850

 cactttatgt agcattgaat gatcaaatat tggatttacc tttaaaaaaa 3900

 aaaaacctga gtatcattgc atgaattttt atctccctat ggttatatcc 3950

 tgcatcaagt ggataatttt gaagtgtgtt cagaatataa aattgaaatt 4000

 ttagagttgt tgaaaatcct gacttgttga aaactaatat atatgtacat 4050

 ggatttctat agatgtgttt gtttagaagt gggtagatat tgcagataag 4100

 actgttcttc agaatcatgt taactattgg gttgtgactg aagtagtgca 4150

 gggtttgcct tgaaaccatt acattctaca tttaccaaat taaacaaata 4200

 aaaactgtat taaatgttgc 4220

<210> 1150
<211> 1186
<212> PRT
<213> Homo sapien

<400> 1150
 Met Ser Lys Leu Lys Val Ile Pro Glu Lys Ser Leu Thr Asn Asn
   1               5                  10                  15

 Ser Arg Ile Val Gly Leu Leu Ala Gln Leu Glu Lys Ile Asn Ala
                  20                  25                  30

 Glu Pro Ser Glu Ser Asp Thr Ala Arg Tyr Val Thr Ser Lys Ile
                  35                  40                  45

 Leu His Leu Ala Gln Ser Gln Glu Lys Thr Arg Arg Glu Met Thr
                  50                  55                  60

 Ala Lys Gly Ser Thr Gly Met Glu Ile Leu Leu Ser Thr Leu Glu
                  65                  70                  75

 Asn Thr Lys Asp Leu Gln Thr Thr Leu Asn Ile Leu Ser Ile Leu
                  80                  85                  90

 Val Glu Leu Val Ser Ala Gly Gly Gly Arg Arg Val Ser Phe Leu
                  95                 100                 105

 Val Thr Lys Gly Gly Ser Gln Ile Leu Leu Gln Leu Leu Met Asn
                 110                 115                 120

 Ala Ser Lys Glu Ser Pro Pro His Glu Asp Leu Met Val Gln Ile
                 125                 130                 135

 His Ser Ile Leu Ala Lys Ile Gly Pro Lys Asp Lys Lys Phe Gly
                 140                 145                 150

 Val Lys Ala Arg Ile Asn Gly Ala Leu Asn Ile Thr Leu Asn Leu
                 155                 160                 165

 Val Lys Gln Asn Leu Gln Asn His Arg Leu Val Leu Pro Cys Leu
                 170                 175                 180

 Gln Leu Leu Arg Val Tyr Ser Ala Asn Ser Val Asn Ser Val Ser
                 185                 190                 195

 Leu Gly Lys Asn Gly Val Val Glu Leu Met Phe Lys Ile Ile Gly
                 200                 205                 210

 Pro Phe Ser Lys Lys Asn Ser Ser Leu Ile Lys Val Ala Leu Asp
                 215                 220                 225

 Thr Leu Ala Ala Leu Leu Lys Ser Lys Thr Asn Ala Arg Arg Ala
                 230                 235                 240

 Val Asp Arg Gly Tyr Val Gln Val Leu Leu Thr Ile Tyr Val Asp
                 245                 250                 255

 Trp His Arg His Asp Asn Arg His Arg Asn Met Leu Ile Arg Lys
                 260                 265                 270

 Gly Ile Leu Arg Ser Leu Lys Ser Val Thr Asn Ile Lys Leu Gly
                 275                 280                 285

 Arg Lys Ala Phe Ile Asp Ala Asn Gly Met Lys Ile Leu Tyr Asn
                 290                 295                 300

 Thr Ser Gln Leu Pro Val Ile Pro Val Thr Gly Pro Val Ala Gln
                 305                 310                 315

 Leu Tyr Ser Leu Pro Pro Glu Val Asp Asp Val Val Asp Glu Ser
                 320                 325                 330

 Asp Asp Asn Asp Asp Ile Asp Val Glu Ala Glu Asn Glu Thr Glu
                 335                 340                 345

 Asn Glu Asp Asp Leu Asp Gln Asn Phe Lys Asn Asp Asp Ile Glu
                 350                 355                 360

 Thr Asp Ile Asn Lys Leu Lys Pro Gln Gln Glu Pro Gly Arg Thr
                 365                 370                 375

 Ile Glu Asp Leu Lys Met Tyr Glu His Leu Phe Pro Glu Leu Val
                 380                 385                 390

 Asp Asp Phe Gln Asp Tyr Asp Leu Ile Ser Lys Glu Pro Lys Pro
                 395                 400                 405

 Phe Val Phe Glu Gly Lys Val Arg Gly Pro Ile Val Val Pro Thr
                 410                 415                 420

 Ala Gly Glu Gly Thr Ser Gly Asn Ser Gly Asn Leu Arg Lys Val
                 425                 430                 435

 Val Met Lys Glu Asn Ile Ser Ser Lys Gly Asp Glu Gly Glu Lys
                 440                 445                 450

 Lys Ser Thr Phe Met Asp Leu Ala Lys Glu Asp Ile Lys Asp Asn
                 455                 460                 465

 Asp Arg Thr Leu Gln Gln Gln Pro Gly Asp Gln Asn Arg Thr Ile
                 470                 475                 480

 Ser Ser Val His Gly Leu Asn Asn Asp Ile Val Lys Ala Leu Asp
                 485                 490                 495

 Arg Ile Thr Leu Gln Asn Ile Pro Ser Gln Thr Ala Pro Gly Phe
                 500                 505                 510

 Thr Ala Glu Met Lys Lys Asp Cys Ser Leu Pro Leu Thr Val Leu
                 515                 520                 525

 Thr Cys Ala Lys Ala Cys Pro His Met Ala Thr Cys Gly Asn Val
                 530                 535                 540

 Leu Phe Glu Gly Arg Thr Val Gln Leu Gly Lys Leu Cys Cys Thr
                 545                 550                 555

 Gly Val Gly Thr Glu Asp Asp Glu Asp Thr Glu Ser Asn Ser Ser
                 560                 565                 570

 Val Glu Gln Ala Ser Val Glu Val Pro Asp Gly Pro Thr Leu His
                 575                 580                 585

 Asp Pro Asp Leu Tyr Ile Glu Ile Val Lys Asn Thr Lys Ser Val
                 590                 595                 600

 Pro Glu Tyr Ser Glu Val Ala Tyr Pro Asp Tyr Phe Gly His Ile
                 605                 610                 615

 Pro Pro Pro Phe Lys Glu Pro Ile Leu Glu Arg Pro Tyr Gly Val
                 620                 625                 630

 Gln Arg Thr Lys Ile Ala Gln Asp Ile Glu Arg Leu Ile His Gln
                 635                 640                 645

 Ser Asp Ile Ile Asp Arg Val Val Tyr Asp Leu Asp Asn Pro Asn
                 650                 655                 660

 Tyr Thr Ile Pro Glu Glu Gly Asp Ile Leu Lys Phe Asn Ser Lys
                 665                 670                 675

 Phe Glu Ser Gly Asn Leu Arg Lys Val Ile Gln Ile Arg Lys Asn
                 680                 685                 690

 Glu Tyr Asp Leu Ile Leu Asn Ser Asp Ile Asn Ser Asn His Tyr
                 695                 700                 705

 His Gln Trp Phe Tyr Phe Glu Val Ser Gly Met Arg Pro Gly Val
                 710                 715                 720

 Ala Tyr Arg Phe Asn Ile Ile Asn Cys Glu Lys Ser Asn Ser Gln
                 725                 730                 735

 Phe Asn Tyr Gly Met Gln Pro Leu Met Tyr Ser Val Gln Glu Ala
                 740                 745                 750

 Leu Asn Ala Arg Pro Trp Trp Ile Arg Met Gly Thr Asp Ile Cys
                 755                 760                 765

 Tyr Tyr Lys Asn His Phe Ser Arg Ser Ser Val Ala Ala Gly Gly
                 770                 775                 780

 Gln Lys Gly Lys Ser Tyr Tyr Thr Ile Thr Phe Thr Val Asn Phe
                 785                 790                 795

 Pro His Lys Asp Asp Val Cys Tyr Phe Ala Tyr His Tyr Pro Tyr
                 800                 805                 810

 Thr Tyr Ser Thr Leu Gln Met His Leu Gln Lys Leu Glu Ser Ala
                 815                 820                 825

 His Asn Pro Gln Gln Ile Tyr Phe Arg Lys Asp Val Leu Cys Glu
                 830                 835                 840

 Thr Leu Ser Gly Asn Ser Cys Pro Leu Val Thr Ile Thr Ala Met
                 845                 850                 855

 Pro Glu Ser Asn Tyr Tyr Glu His Ile Cys His Phe Arg Asn Arg
                 860                 865                 870

 Pro Tyr Val Phe Leu Ser Ala Arg Val His Pro Gly Glu Thr Asn
                 875                 880                 885

 Ala Ser Trp Val Met Lys Gly Thr Leu Glu Tyr Leu Met Ser Asn
                 890                 895                 900

 Asn Pro Thr Ala Gln Ser Leu Arg Glu Ser Tyr Ile Phe Lys Ile
                 905                 910                 915

 Val Pro Met Leu Asn Pro Asp Gly Val Ile Asn Gly Asn His Arg
                 920                 925                 930

 Cys Ser Leu Ser Gly Glu Asp Leu Asn Arg Gln Trp Gln Ser Pro
                 935                 940                 945

 Ser Pro Asp Leu His Pro Thr Ile Tyr His Ala Lys Gly Leu Leu
                 950                 955                 960

 Gln Tyr Leu Ala Ala Val Lys Arg Leu Pro Leu Val Tyr Cys Asp
                 965                 970                 975

 Tyr His Gly His Ser Arg Lys Lys Asn Val Phe Met Tyr Gly Cys
                 980                 985                 990

 Ser Ile Lys Glu Thr Val Trp His Thr Asn Asp Asn Ala Thr Ser
                 995                1000                1005

 Cys Asp Val Val Glu Asp Thr Gly Tyr Arg Thr Leu Pro Lys Ile
                1010                1015                1020

 Leu Ser His Ile Ala Pro Ala Phe Cys Met Ser Ser Cys Ser Phe
                1025                1030                1035

 Val Val Glu Lys Ser Lys Glu Ser Thr Ala Arg Val Val Val Trp
                1040                1045                1050

 Arg Glu Ile Gly Val Gln Arg Ser Tyr Thr Met Glu Ser Thr Leu
                1055                1060                1065

 Cys Gly Cys Asp Gln Gly Lys Tyr Lys Gly Leu Gln Ile Gly Thr
                1070                1075                1080

 Arg Glu Leu Glu Glu Met Gly Ala Lys Phe Cys Val Gly Leu Leu
                1085                1090                1095

 Arg Leu Lys Arg Leu Thr Ser Pro Leu Glu Tyr Asn Leu Pro Ser
                1100                1105                1110

 Ser Leu Leu Asp Phe Glu Asn Asp Leu Ile Glu Ser Ser Cys Lys
                1115                1120                1125

 Val Thr Ser Pro Thr Thr Tyr Val Leu Asp Glu Asp Glu Pro Arg
                1130                1135                1140

 Phe Leu Glu Glu Val Asp Tyr Ser Ala Glu Ser Asn Asp Glu Leu
                1145                1150                1155

 Asp Ile Glu Leu Ala Glu Asn Val Gly Asp Tyr Glu Pro Ser Ala
                1160                1165                1170

 Gln Glu Glu Val Leu Ser Asp Ser Glu Leu Ser Arg Thr Tyr Leu
                1175                1180                1185

 Pro


<210> 1151
<211> 3178
<212> DNA
<213> Homo sapien

<400> 1151
 gatctcttgg agacggcgac ccaggcatct ggggagccac agaagtcgta 50

 ctcccttaaa ccctgctttg ctccccctgt ggatgtaacc ccttagctgg 100

 cattttgcat ctcaattggc ttgtgatgga ggcgtctttg gggattcaga 150

 tggatgagcc aatggctttt tctccccagc gtgaccggtt tcaggctgaa 200

 ggctctttaa aaaaaaacga gcagaatttt aaacttgcag gtgttaaaaa 250

 agatattgag aagctttatg aagctgtacc acagcttagt aatgtgttta 300

 agattgagga caaaattgga gaaggcactt tcagctctgt ttatttggcc 350

 acagcacagt tacaagtagg acctgaagag aaaattgctc taaaacactt 400

 gattccaaca agtcatccta taagaattgc agctgaactt cagtgcctaa 450

 cagtggctgg ggggcaagat aatgtcatgg gagttaaata ctgctttagg 500

 aagaatgatc atgtagttat tgctatgcca tatctggagc atgagtcgtt 550

 tttggacatt ctgaattctc tttcctttca agaagtacgg gaatatatgc 600

 ttaatctgtt caaagctttg aaacgcattc atcagtttgg tattgttcac 650

 cgtgatgtta agcccagcaa ttttttatat aataggcgcc tgaaaaagta 700

 tgccttggta gactttggtt tggcccaagg aacccatgat acgaaaatag 750

 agcttcttaa atttgtccag tctgaagctc agcaggaaag gtgttcacaa 800

 aacaaatccc acataatcac aggaaacaag attccactga gtggcccagt 850

 acctaaggag ctggatcagc agtccaccac aaaagcttct gttaaaagac 900

 cctacacaaa tgcacaaatt cagattaaac aaggaaaaga cggaaaggag 950

 ggatctgtag gcctttctgt ccagcgctct gtttttggag aaagaaattt 1000

 caatatacac agctccattt cacatgagag ccctgcagtg aaactcatga 1050

 agcagtcaaa gactgtggat gtactgtcta gaaagttagc aacaaaaaag 1100

 aaggctattt ctacgaaagt tatgaatagt gctgtgatga ggaaaactgc 1150

 cagttcttgc ccagctagcc tgacctgtga ctgctatgca acagataaag 1200

 tttgtagtat ttgcctttca aggcgtcagc aggttgcccc tagggcaggt 1250

 acaccaggat tcagagcacc agaggtcttg acaaagtgcc ccaatcaaac 1300

 tacagcaatt gacatgtggt ctgcaggtgt catatttctt tctttgctta 1350

 gtggacgata tccattttat aaagcaagtg atgatttaac tgctttggcc 1400

 caaattatga caattagggg atccagagaa actatccaag ctgctaaaac 1450

 ttttgggaaa tcaatattat gtagcaaaga agttccagca caagacttga 1500

 gaaaactctg tgagagactc aggggtatgg attctagcac tcccaagtta 1550

 acaagtgata tacaagggca tgcttctcat caaccagcta tttcagagaa 1600

 gactgaccat aaagcttctt gcctcgttca aacacctcca ggacaatact 1650

 cagggaattc atttaaaaag ggggatagta atagctgtga gcattgtttt 1700

 gatgagtata ataccaattt agaaggctgg aatgaggtac ctgatgaagc 1750

 ttatgacctg cttgataaac ttctagatct aaatccagct tcaagaataa 1800

 cagcagaaga agctttgttg catccatttt ttaaagatat gagcttgtga 1850

 taatggatct tcatttaatg tttactgtta tgaggtagaa taaaaaagaa 1900

 tactttgtaa tagccacaag ttcttgttta gagaccagag caggattaat 1950

 aatttatttt aacattttag tgtttggtgg cacattctaa aatatagatt 2000

 aagaatactt aaaatgcctg ggatagttct tgggactaac aacatgatct 2050

 tctttgagtt aaacctacct aagtagattt taggtgggtt cctattaggt 2100

 cagattttta gcttccctaa ttacctttca ctgacataca gaaaaaggag 2150

 cagttttagt tttaattaat taaaattaac agatgtgatg aggattaaat 2200

 gaatcaaaag acttaatttg tagattcttt tagagttatg agctaggtat 2250

 agtttgggga aactcaacct ggtgctggtg ctcttaacaa ttttgtaaat 2300

 aaagaagata atttcctttt ctagaggtac atattaggcc ttttatgaac 2350

 actaaaacaa tgaggaaatg ttggtcatgg ggcaaagtat cacttaaaat 2400

 tgaattcatc catttttaaa aaacacttca tgaaagcatt ctggtgtgaa 2450

 ttgccatttt tttcttactg gcttctcaat tttcttcctt ctctgcccct 2500

 acctaaaaca ttctcctcgg aaattacatg gtgctgacca caaagtttct 2550

 ggatgtttta ttaaatattg tacgtgttta cagttgggaa tttaaaataa 2600

 tacatacact ggttgataaa gggaagctgc aggaccaagg tgaagattga 2650

 tagtccaaat gcttttcttt tttgagttgt atattttttc acaccatctt 2700

 agatataatt aggtagctgc tgaaaggaaa agtgaataca gaattgacgg 2750

 tattattgga gatttttcct ctgcgtagag ccatccagat ctctgtatcc 2800

 tgttttgact aagtcttagg tgggttggga agacagataa tgaagtaggc 2850

 aaagagaaaa ggacccaaga tagaggttta tattcagaaa tggtatatat 2900

 caatgacagc atatcaaact tcctatggga aaaagtctgg tgggtggtca 2950

 gctgacagat ttcccattta gtagtcatag aatacagaaa tagtttaggg 3000

 acatgtattc attttgttat tttgagcatt gataggtcag tatatctacc 3050

 taatctgttt ggtaagtata ggatatataa accattacca ttgatctgtc 3100

 ttatgccata atcttaaaaa aaaattgaat gctcttgaat ttgtatattc 3150

 aataaagtta tccttttata aaaaaaaa 3178

<210> 1152
<211> 574
<212> PRT
<213> Homo sapien

<400> 1152
 Met Glu Ala Ser Leu Gly Ile Gln Met Asp Glu Pro Met Ala Phe
   1               5                  10                  15

 Ser Pro Gln Arg Asp Arg Phe Gln Ala Glu Gly Ser Leu Lys Lys
                  20                  25                  30

 Asn Glu Gln Asn Phe Lys Leu Ala Gly Val Lys Lys Asp Ile Glu
                  35                  40                  45

 Lys Leu Tyr Glu Ala Val Pro Gln Leu Ser Asn Val Phe Lys Ile
                  50                  55                  60

 Glu Asp Lys Ile Gly Glu Gly Thr Phe Ser Ser Val Tyr Leu Ala
                  65                  70                  75

 Thr Ala Gln Leu Gln Val Gly Pro Glu Glu Lys Ile Ala Leu Lys
                  80                  85                  90

 His Leu Ile Pro Thr Ser His Pro Ile Arg Ile Ala Ala Glu Leu
                  95                 100                 105

 Gln Cys Leu Thr Val Ala Gly Gly Gln Asp Asn Val Met Gly Val
                 110                 115                 120

 Lys Tyr Cys Phe Arg Lys Asn Asp His Val Val Ile Ala Met Pro
                 125                 130                 135

 Tyr Leu Glu His Glu Ser Phe Leu Asp Ile Leu Asn Ser Leu Ser
                 140                 145                 150

 Phe Gln Glu Val Arg Glu Tyr Met Leu Asn Leu Phe Lys Ala Leu
                 155                 160                 165

 Lys Arg Ile His Gln Phe Gly Ile Val His Arg Asp Val Lys Pro
                 170                 175                 180

 Ser Asn Phe Leu Tyr Asn Arg Arg Leu Lys Lys Tyr Ala Leu Val
                 185                 190                 195

 Asp Phe Gly Leu Ala Gln Gly Thr His Asp Thr Lys Ile Glu Leu
                 200                 205                 210

 Leu Lys Phe Val Gln Ser Glu Ala Gln Gln Glu Arg Cys Ser Gln
                 215                 220                 225

 Asn Lys Ser His Ile Ile Thr Gly Asn Lys Ile Pro Leu Ser Gly
                 230                 235                 240

 Pro Val Pro Lys Glu Leu Asp Gln Gln Ser Thr Thr Lys Ala Ser
                 245                 250                 255

 Val Lys Arg Pro Tyr Thr Asn Ala Gln Ile Gln Ile Lys Gln Gly
                 260                 265                 270

 Lys Asp Gly Lys Glu Gly Ser Val Gly Leu Ser Val Gln Arg Ser
                 275                 280                 285

 Val Phe Gly Glu Arg Asn Phe Asn Ile His Ser Ser Ile Ser His
                 290                 295                 300

 Glu Ser Pro Ala Val Lys Leu Met Lys Gln Ser Lys Thr Val Asp
                 305                 310                 315

 Val Leu Ser Arg Lys Leu Ala Thr Lys Lys Lys Ala Ile Ser Thr
                 320                 325                 330

 Lys Val Met Asn Ser Ala Val Met Arg Lys Thr Ala Ser Ser Cys
                 335                 340                 345

 Pro Ala Ser Leu Thr Cys Asp Cys Tyr Ala Thr Asp Lys Val Cys
                 350                 355                 360

 Ser Ile Cys Leu Ser Arg Arg Gln Gln Val Ala Pro Arg Ala Gly
                 365                 370                 375

 Thr Pro Gly Phe Arg Ala Pro Glu Val Leu Thr Lys Cys Pro Asn
                 380                 385                 390

 Gln Thr Thr Ala Ile Asp Met Trp Ser Ala Gly Val Ile Phe Leu
                 395                 400                 405

 Ser Leu Leu Ser Gly Arg Tyr Pro Phe Tyr Lys Ala Ser Asp Asp
                 410                 415                 420

 Leu Thr Ala Leu Ala Gln Ile Met Thr Ile Arg Gly Ser Arg Glu
                 425                 430                 435

 Thr Ile Gln Ala Ala Lys Thr Phe Gly Lys Ser Ile Leu Cys Ser
                 440                 445                 450

 Lys Glu Val Pro Ala Gln Asp Leu Arg Lys Leu Cys Glu Arg Leu
                 455                 460                 465

 Arg Gly Met Asp Ser Ser Thr Pro Lys Leu Thr Ser Asp Ile Gln
                 470                 475                 480

 Gly His Ala Ser His Gln Pro Ala Ile Ser Glu Lys Thr Asp His
                 485                 490                 495

 Lys Ala Ser Cys Leu Val Gln Thr Pro Pro Gly Gln Tyr Ser Gly
                 500                 505                 510

 Asn Ser Phe Lys Lys Gly Asp Ser Asn Ser Cys Glu His Cys Phe
                 515                 520                 525

 Asp Glu Tyr Asn Thr Asn Leu Glu Gly Trp Asn Glu Val Pro Asp
                 530                 535                 540

 Glu Ala Tyr Asp Leu Leu Asp Lys Leu Leu Asp Leu Asn Pro Ala
                 545                 550                 555

 Ser Arg Ile Thr Ala Glu Glu Ala Leu Leu His Pro Phe Phe Lys
                 560                 565                 570

 Asp Met Ser Leu


<210> 1153
<211> 2407
<212> DNA
<213> Homo sapien

<400> 1153
 ctaaaggtcg gcgaggcttc tgaagacgca attcctgcga cgcccgcgga 50

 ggggccctgg ggggcggcgc gagcgtctgg cctgtgttgg ctgtaggcaa 100

 cgaaaggagc cctcccggtc tgcgccggat ggccccgggc ggtgactcgg 150

 tccggagccc tggaacgcta cgcccacctg gcggaaagca ccacggaaac 200

 gcatccttct gtggccactg ttaggtctgc cattttacac ttttctgatc 250

 tcctccttcc cttctgtgag ctatgtctca ggggtcagtg acattcagag 300

 atgtggccat agacttctcc caggaggagt ggaaatggct tcagcctgct 350

 caaagagatt tgtacagatg tgtaatgttg gagaactatg gccatctggt 400

 ctcactgggt ctttccattt ctaagccaga tgtggtttcc ttattggagc 450

 aagggaaaga accctggctg gggaaaaggg aagtgaaaag agatctgttt 500

 tcagtttcag agtcaagtgg tgagatcaaa gacttttcac caaaaaatgt 550

 catttatgat gactcatccc agtatttgat catggaaaga attctaagtc 600

 aaggccctgt gtattccagt tttaaaggag gctggaaatg caaggatcat 650

 actgagatgc tgcaagaaaa tcagggatgt attaggaaag taacagtctc 700

 tcatcaagaa gccctggctc aacatatgaa tatcagtact gtggagaggc 750

 cctatggatg ccatgaatgt ggaaaaactt ttggtcgacg cttttccctg 800

 gtgttacacc agaggactca tactggagag aaaccatatg catgtaagga 850

 atgtggcaaa acctttagcc agatttcaaa ccttgtgaaa caccaaatga 900

 tacatactgg aaagaaaccc catgagtgta aggactgtaa taaaacattc 950

 agttaccttt catttcttat tgaacaccag agaacgcaca ctggggagaa 1000

 accttatgaa tgtactgagt gtggaaaggc ctttagccgt gcctccaacc 1050

 tcactcgaca tcaaagaatt cacataggaa agaaacaata tatatgtagg 1100

 aaatgtggta aagcatttag cagtggctca gaactcattc gccaccagat 1150

 tacacatact ggagagaaac cttatgaatg cattgaatgt gggaaggcat 1200

 ttcgccgttt ctcacacctt actcgacatc agagcatcca tacaaccaaa 1250

 accccgtatg aatgtaatga atgtaggaaa gctttgcgtt gtcactcatt 1300

 ccttattaaa catcagagaa ttcatgctgg agaaaagctc tatgaatgtg 1350

 atgaatgtgg taaagttttc acttggcatg catcccttat tcaacatacg 1400

 aagagtcaca ctggagagaa accctatgcg tgtgctgaat gtgataaagc 1450

 cttcagccgg agcttttccc tcattctaca tcagagaact catactggag 1500

 agaaacccta tgtatgtaag gtatgcaaca aatccttcag ctggagctca 1550

 aaccttgcta aacatcagag gacacacact cttgacaacc cctatgaata 1600

 tgaaaattca tttaattacc actcattcct tactgaacac cagtgaattt 1650

 acactgcaaa gaaaaactat gaatgtatgg aattttttaa aaagaagtat 1700

 aatgccttac ttcagagaac tcttggaaag aagccttatg tgaaagtgat 1750

 gactgtgaag taatatggcc cacactttat tcaccaccct ggagaaaaaa 1800

 aaacccagga atatgtggaa aagccattaa taaccactct tttatttttt 1850

 tgcaataaca aggtgaaatc aatattgttg agaagattct tccatctggt 1900

 aatgttgaga agacttcatt tggtaggagt cccttacttt acgtgtgtaa 1950

 attcctacca ggaaagaata catatccaat agattggaga aagccagaga 2000

 ttagccccgc attccgcatc tgtcaaccag gacagaaagc atggacaagg 2050

 gatgagcttt acaaagatga tgcactttgg agatcagaaa attcatattt 2100

 aagcaaagtg atacaaacac agtgatttgg gaatgccttc atttacaatg 2150

 caatacttac attttaatac tcttgtagga gaaaaagcaa ctgtataaat 2200

 gaatgtagag tgactttctg caatatttgc aacctatatc agagaattac 2250

 actgtgggaa aactaccatt gtaataagtg tagcaaaatc tccttagata 2300

 tctgaaaagt catactggat ggaatctgta ggaaacggtt ctattttgag 2350

 ggaaggggga ttcctttttg ttttttaagt gaattcagaa aatgttataa 2400

 actttag 2407

<210> 1154
<211> 457
<212> PRT
<213> Homo sapien

<400> 1154
 Met Ser Gln Gly Ser Val Thr Phe Arg Asp Val Ala Ile Asp Phe
   1               5                  10                  15

 Ser Gln Glu Glu Trp Lys Trp Leu Gln Pro Ala Gln Arg Asp Leu
                  20                  25                  30

 Tyr Arg Cys Val Met Leu Glu Asn Tyr Gly His Leu Val Ser Leu
                  35                  40                  45

 Gly Leu Ser Ile Ser Lys Pro Asp Val Val Ser Leu Leu Glu Gln
                  50                  55                  60

 Gly Lys Glu Pro Trp Leu Gly Lys Arg Glu Val Lys Arg Asp Leu
                  65                  70                  75

 Phe Ser Val Ser Glu Ser Ser Gly Glu Ile Lys Asp Phe Ser Pro
                  80                  85                  90

 Lys Asn Val Ile Tyr Asp Asp Ser Ser Gln Tyr Leu Ile Met Glu
                  95                 100                 105

 Arg Ile Leu Ser Gln Gly Pro Val Tyr Ser Ser Phe Lys Gly Gly
                 110                 115                 120

 Trp Lys Cys Lys Asp His Thr Glu Met Leu Gln Glu Asn Gln Gly
                 125                 130                 135

 Cys Ile Arg Lys Val Thr Val Ser His Gln Glu Ala Leu Ala Gln
                 140                 145                 150

 His Met Asn Ile Ser Thr Val Glu Arg Pro Tyr Gly Cys His Glu
                 155                 160                 165

 Cys Gly Lys Thr Phe Gly Arg Arg Phe Ser Leu Val Leu His Gln
                 170                 175                 180

 Arg Thr His Thr Gly Glu Lys Pro Tyr Ala Cys Lys Glu Cys Gly
                 185                 190                 195

 Lys Thr Phe Ser Gln Ile Ser Asn Leu Val Lys His Gln Met Ile
                 200                 205                 210

 His Thr Gly Lys Lys Pro His Glu Cys Lys Asp Cys Asn Lys Thr
                 215                 220                 225

 Phe Ser Tyr Leu Ser Phe Leu Ile Glu His Gln Arg Thr His Thr
                 230                 235                 240

 Gly Glu Lys Pro Tyr Glu Cys Thr Glu Cys Gly Lys Ala Phe Ser
                 245                 250                 255

 Arg Ala Ser Asn Leu Thr Arg His Gln Arg Ile His Ile Gly Lys
                 260                 265                 270

 Lys Gln Tyr Ile Cys Arg Lys Cys Gly Lys Ala Phe Ser Ser Gly
                 275                 280                 285

 Ser Glu Leu Ile Arg His Gln Ile Thr His Thr Gly Glu Lys Pro
                 290                 295                 300

 Tyr Glu Cys Ile Glu Cys Gly Lys Ala Phe Arg Arg Phe Ser His
                 305                 310                 315

 Leu Thr Arg His Gln Ser Ile His Thr Thr Lys Thr Pro Tyr Glu
                 320                 325                 330

 Cys Asn Glu Cys Arg Lys Ala Leu Arg Cys His Ser Phe Leu Ile
                 335                 340                 345

 Lys His Gln Arg Ile His Ala Gly Glu Lys Leu Tyr Glu Cys Asp
                 350                 355                 360

 Glu Cys Gly Lys Val Phe Thr Trp His Ala Ser Leu Ile Gln His
                 365                 370                 375

 Thr Lys Ser His Thr Gly Glu Lys Pro Tyr Ala Cys Ala Glu Cys
                 380                 385                 390

 Asp Lys Ala Phe Ser Arg Ser Phe Ser Leu Ile Leu His Gln Arg
                 395                 400                 405

 Thr His Thr Gly Glu Lys Pro Tyr Val Cys Lys Val Cys Asn Lys
                 410                 415                 420

 Ser Phe Ser Trp Ser Ser Asn Leu Ala Lys His Gln Arg Thr His
                 425                 430                 435

 Thr Leu Asp Asn Pro Tyr Glu Tyr Glu Asn Ser Phe Asn Tyr His
                 440                 445                 450

 Ser Phe Leu Thr Glu His Gln
                 455

<210> 1155
<211> 4133
<212> DNA
<213> Homo sapien

<400> 1155
 ggtgcgcgcc gcggcttggg ggagagttga gcgcttttcc cccctctttt 50

 tttttttttt ttcctcttct tcttaaacaa accacaaacg gatgtgaggg 100

 aaggaaggtg tttcttttac tcctgagccc agacacctca ctctgttccg 150

 tctaagcttg ttttgctgaa cacttttttt taaaaaagga aaaagaaaag 200

 gagttgcttg atgtgagagt gaaatggacg taagatttta tccacctcca 250

 gcccagcccg ccgctgcgcc cgacgctccc tgtctgggac cttctccctg 300

 cctggacccc tactattgca acaagtttga cggtgagaac atgtatatga 350

 gcatgacaga gccgagccag gactatgtgc cagccagcca gtcctaccct 400

 ggtccaagcc tggaaagtga agacttcaac attccaccaa ttactcctcc 450

 ttccctccca gaccactcgc tggtgcacct gaatgaagtt gagtctggtt 500

 accattctct gtgtcacccc atgaaccata atggcctgct accatttcat 550

 ccacaaaaca tggacctccc tgaaatcaca gtctccaata tgctgggcca 600

 ggatggaaca ctgctttcta attccatttc tgtgatgcca gatatacgaa 650

 acccagaagg aactcagtac agttcccatc ctcagatggc agccatgaga 700

 ccaaggggcc agcctgcaga catcaggcag cagccaggaa tgatgccaca 750

 tggccagctg actaccatta accagtcaca gctaagtgct caacttggtt 800

 tgaatatggg aggaagcaat gttccccaca actcaccatc tccacctgga 850

 agcaagtctg caactccttc accatccagt tcagtgcatg aagatgaagg 900

 cgatgatacc tctaagatca atggtggaga gaagcggcct gcctctgata 950

 tggggaaaaa accaaaaact cccaaaaaga agaagaagaa ggatcccaat 1000

 gagccccaga agcctgtgtc tgcctatgcg ttattctttc gtgatactca 1050

 ggccgccatc aagggccaaa atccaaacgc tacctttggc gaagtctcta 1100

 aaattgtggc ttcaatgtgg gacggtttag gagaagagca aaaacaggtc 1150

 tataaaaaga aaaccgaggc tgcgaagaag gagtacctga agcaactcgc 1200

 agcatacaga gccagccttg tatccaagag ctacagtgaa cctgttgacg 1250

 tgaagacatc tcaacctcct cagctgatca attcgaagcc gtcggtgttc 1300

 catgggccca gccaggccca ctcggccctg tacctaagtt cccactatca 1350

 ccaacaaccg ggaatgaatc ctcacctaac tgccatgcat cctagtctcc 1400

 ccaggaacat agcccccaag ccgaataacc aaatgccagt gactgtctct 1450

 atagcaaaca tggctgtgtc ccctcctcct cccctccaga tcagcccgcc 1500

 tcttcaccag catctcaaca tgcagcagca ccagccgctc accatgcagc 1550

 agccccttgg gaaccagctc cccatgcagg tccagtctgc cttacactca 1600

 cccaccatgc agcaaggatt tactcttcaa cccgactatc agactattat 1650

 caatcctaca tctacagctg cacaagttgt cacccaggca atggagtatg 1700

 tgcgttcggg gtgcagaaat cctcccccac aaccggtgga ctggaataac 1750

 gactactgca gtagtggggg catgcagagg gacaaagcac tgtaccttac 1800

 ttgagaatct gaacacctct tctttccact gaggaattca gggaagtgtt 1850

 ttcaccatgg attgctttgt acagtcaagg cagttctcca ttttattaga 1900

 aaatacaagt tgctaagcac ttaggaccat ttgagcttgt gggtcaccca 1950

 ctctggaaga aatagtcatg cttctttatt atttttttaa tcctttatgg 2000

 acattgtttt tcttcttccc tgaaggaaat ttggaccatt cagattttat 2050

 gttggttttt tgctgtgaag tgctgcgctc tagtaactgc cttagcaact 2100

 gtagatgtct cggataaaag tcctggattt tccattggtt ttcataatgg 2150

 gtgtttatat gaaactacta aagacttttt aaatggcttg atgtagcagt 2200

 catagcaagt ttgtaaatag catctatgtt acactctcct agagtataaa 2250

 atgtgaatgt ttttgtagct aaattgtaat tgaaactggc tcattccagt 2300

 ttattgattt cacaataggg gttaaattgg caaacattca tatttttact 2350

 tcatttttaa aacaactgac tgatagttct atattttcaa aatatttgaa 2400

 aataaaaagt attcccaagt gattttaatt taaaaacaaa ttggctttgt 2450

 ctcattgatc agacaaaaag aaactagtat taagggaagc gcaaacacat 2500

 ttattttgta ctgcagaaaa attgcttttt tgtatcactt tttgtgtaat 2550

 ggttagtaaa tgtcatttaa gtccttttat gtataaaact gccaaatgct 2600

 tacctggtat tttattagat gcagaaacag attggaaaca gctaaattac 2650

 aacttttaca tatggctctg tcttattgtt tcttcatact gtgtctgtat 2700

 ttaatctttt tttatggaac ctgttgcgcc tatttatgaa ataataaata 2750

 taggtgtttg taagtaaatt tgttagtatt tgaaagaggt ttctttgatg 2800

 ttttaacttt tgctggcaaa aaaaaattca cgcttggtgt gaatacttta 2850

 ttatttagtt tttacagtaa catgaataaa gccaaacctg cttttcattt 2900

 agcagcaaat taaagtaacc agtccttatt tctgcatttc tttggttgat 2950

 gcaaacaaaa aactattata tttaagaact ttatttcttc atacgacata 3000

 acagaattgc cctccaagtc acacaagctc caagactaaa caaacagaca 3050

 ggtcctctgt cttaaaaagg ttacttcttg gttctcagct ggttctagtc 3100

 aattctgaac caccaccccc cgccccccgc aaaaaagtaa aagtcaaacc 3150

 aaacttcctc aagctgcatg cttttcacaa aatccagaaa gcatttaaga 3200

 attgaactag gggctggaag aagtgaaagg gaagcatcta aaaatgaaag 3250

 gtgagtaacc agatagcaaa agaaaaggga aagccatcca aatttgaaag 3300

 ctgttgatag aaattgagat tcttgctgtc ttttgtgcct ctgcaagcta 3350

 ctactcattc cagaattcct gggtcttcca agaggattct taaggtacca 3400

 gagatttgct agggaaccaa aagtgcttga gaatctgcct gagggcttgc 3450

 atagctttca cattaaaaaa agaaaaagct agcagattta ctccttttta 3500

 ggggatcata tcaagaaagt tagtctggtt ggaaaccaag agaatggctg 3550

 atgtctcttt cttggaatat gtgaaataaa tttagcagtt taactaaata 3600

 caaatatatg cattgtgtaa tccactcaga attaaacaga caaaaggtat 3650

 gcttgctttg gaatgatttt aggcattgta caaccttgaa tcacttgagc 3700

 atgtaataac taataaataa tgcagatcca tgtgattatt aaaatgactg 3750

 tagctgagag ctctaatttt cctgtcttga aactgtataa gaactcatgt 3800

 gattaagttc acagtttatt gtttgtctgt ttagtatttt agaaatatac 3850

 cagcactact aattaactaa tgtcttttat ttattatatt atgataaagt 3900

 aaaaatttca cttgcattaa gtctaaactg agaaggtaat tactgggagg 3950

 agaatgagca gctttgactt tgacaggcgg tttgtgcagg aaagcacagt 4000

 gccgtgttgt ttacagcttt tctagagcag ctgtgcgacc agggtagaga 4050

 gtgttgaaat tcaataccaa atacagtaaa aacaaatgta aataaaagaa 4100

 aacacatcat caataaaact gttattatgc gtg 4133

<210> 1156
<211> 526
<212> PRT
<213> Homo sapien

<400> 1156
 Met Asp Val Arg Phe Tyr Pro Pro Pro Ala Gln Pro Ala Ala Ala
   1               5                  10                  15

 Pro Asp Ala Pro Cys Leu Gly Pro Ser Pro Cys Leu Asp Pro Tyr
                  20                  25                  30

 Tyr Cys Asn Lys Phe Asp Gly Glu Asn Met Tyr Met Ser Met Thr
                  35                  40                  45

 Glu Pro Ser Gln Asp Tyr Val Pro Ala Ser Gln Ser Tyr Pro Gly
                  50                  55                  60

 Pro Ser Leu Glu Ser Glu Asp Phe Asn Ile Pro Pro Ile Thr Pro
                  65                  70                  75

 Pro Ser Leu Pro Asp His Ser Leu Val His Leu Asn Glu Val Glu
                  80                  85                  90

 Ser Gly Tyr His Ser Leu Cys His Pro Met Asn His Asn Gly Leu
                  95                 100                 105

 Leu Pro Phe His Pro Gln Asn Met Asp Leu Pro Glu Ile Thr Val
                 110                 115                 120

 Ser Asn Met Leu Gly Gln Asp Gly Thr Leu Leu Ser Asn Ser Ile
                 125                 130                 135

 Ser Val Met Pro Asp Ile Arg Asn Pro Glu Gly Thr Gln Tyr Ser
                 140                 145                 150

 Ser His Pro Gln Met Ala Ala Met Arg Pro Arg Gly Gln Pro Ala
                 155                 160                 165

 Asp Ile Arg Gln Gln Pro Gly Met Met Pro His Gly Gln Leu Thr
                 170                 175                 180

 Thr Ile Asn Gln Ser Gln Leu Ser Ala Gln Leu Gly Leu Asn Met
                 185                 190                 195

 Gly Gly Ser Asn Val Pro His Asn Ser Pro Ser Pro Pro Gly Ser
                 200                 205                 210

 Lys Ser Ala Thr Pro Ser Pro Ser Ser Ser Val His Glu Asp Glu
                 215                 220                 225

 Gly Asp Asp Thr Ser Lys Ile Asn Gly Gly Glu Lys Arg Pro Ala
                 230                 235                 240

 Ser Asp Met Gly Lys Lys Pro Lys Thr Pro Lys Lys Lys Lys Lys
                 245                 250                 255

 Lys Asp Pro Asn Glu Pro Gln Lys Pro Val Ser Ala Tyr Ala Leu
                 260                 265                 270

 Phe Phe Arg Asp Thr Gln Ala Ala Ile Lys Gly Gln Asn Pro Asn
                 275                 280                 285

 Ala Thr Phe Gly Glu Val Ser Lys Ile Val Ala Ser Met Trp Asp
                 290                 295                 300

 Gly Leu Gly Glu Glu Gln Lys Gln Val Tyr Lys Lys Lys Thr Glu
                 305                 310                 315

 Ala Ala Lys Lys Glu Tyr Leu Lys Gln Leu Ala Ala Tyr Arg Ala
                 320                 325                 330

 Ser Leu Val Ser Lys Ser Tyr Ser Glu Pro Val Asp Val Lys Thr
                 335                 340                 345

 Ser Gln Pro Pro Gln Leu Ile Asn Ser Lys Pro Ser Val Phe His
                 350                 355                 360

 Gly Pro Ser Gln Ala His Ser Ala Leu Tyr Leu Ser Ser His Tyr
                 365                 370                 375

 His Gln Gln Pro Gly Met Asn Pro His Leu Thr Ala Met His Pro
                 380                 385                 390

 Ser Leu Pro Arg Asn Ile Ala Pro Lys Pro Asn Asn Gln Met Pro
                 395                 400                 405

 Val Thr Val Ser Ile Ala Asn Met Ala Val Ser Pro Pro Pro Pro
                 410                 415                 420

 Leu Gln Ile Ser Pro Pro Leu His Gln His Leu Asn Met Gln Gln
                 425                 430                 435

 His Gln Pro Leu Thr Met Gln Gln Pro Leu Gly Asn Gln Leu Pro
                 440                 445                 450

 Met Gln Val Gln Ser Ala Leu His Ser Pro Thr Met Gln Gln Gly
                 455                 460                 465

 Phe Thr Leu Gln Pro Asp Tyr Gln Thr Ile Ile Asn Pro Thr Ser
                 470                 475                 480

 Thr Ala Ala Gln Val Val Thr Gln Ala Met Glu Tyr Val Arg Ser
                 485                 490                 495

 Gly Cys Arg Asn Pro Pro Pro Gln Pro Val Asp Trp Asn Asn Asp
                 500                 505                 510

 Tyr Cys Ser Ser Gly Gly Met Gln Arg Asp Lys Ala Leu Tyr Leu
                 515                 520                 525

 Thr


<210> 1157
<211> 1172
<212> DNA
<213> Homo sapien

<400> 1157
 gagacattcc tcaattgctt agacatattc tgagcctaca gcagaggaac 50

 ctccagtctc agcaccatga atcaaactgc gattctgatt tgctgcctta 100

 tctttctgac tctaagtggc attcaaggag tacctctctc tagaaccgta 150

 cgctgtacct gcatcagcat tagtaatcaa cctgttaatc caaggtcttt 200

 agaaaaactt gaaattattc ctgcaagcca attttgtcca cgtgttgaga 250

 tcattgctac aatgaaaaag aagggtgaga agagatgtct gaatccagaa 300

 tcgaaggcca tcaagaattt actgaaagca gttagcaagg aaatgtctaa 350

 aagatctcct taaaaccaga ggggagcaaa atcgatgcag tgcttccaag 400

 gatggaccac acagaggctg cctctcccat cacttcccta catggagtat 450

 atgtcaagcc ataattgttc ttagtttgca gttacactaa aaggtgacca 500

 atgatggtca ccaaatcagc tgctactact cctgtaggaa ggttaatgtt 550

 catcatccta agctattcag taataactct accctggcac tataatgtaa 600

 gctctactga ggtgctatgt tcttagtgga tgttctgacc ctgcttcaaa 650

 tatttccctc acctttccca tcttccaagg gtactaagga atctttctgc 700

 tttggggttt atcagaattc tcagaatctc aaataactaa aaggtatgca 750

 atcaaatctg ctttttaaag aatgctcttt acttcatgga cttccactgc 800

 catcctccca aggggcccaa attctttcag tggctaccta catacaattc 850

 caaacacata caggaaggta gaaatatctg aaaatgtatg tgtaagtatt 900

 cttatttaat gaaagactgt acaaagtata agtcttagat gtatatattt 950

 cctatattgt tttcagtgta catggaataa catgtaatta agtactatgt 1000

 atcaatgagt aacaggaaaa ttttaaaaat acagatagat atatgctctg 1050

 catgttacat aagataaatg tgctgaatgg ttttcaaata aaaatgaggt 1100

 actctcctgg aaatattaag aaagactatc taaatgttga aagatcaaaa 1150

 ggttaataaa gtaattataa ct 1172

<210> 1158
<211> 98
<212> PRT
<213> Homo sapien

<400> 1158
 Met Asn Gln Thr Ala Ile Leu Ile Cys Cys Leu Ile Phe Leu Thr
   1               5                  10                  15

 Leu Ser Gly Ile Gln Gly Val Pro Leu Ser Arg Thr Val Arg Cys
                  20                  25                  30

 Thr Cys Ile Ser Ile Ser Asn Gln Pro Val Asn Pro Arg Ser Leu
                  35                  40                  45

 Glu Lys Leu Glu Ile Ile Pro Ala Ser Gln Phe Cys Pro Arg Val
                  50                  55                  60

 Glu Ile Ile Ala Thr Met Lys Lys Lys Gly Glu Lys Arg Cys Leu
                  65                  70                  75

 Asn Pro Glu Ser Lys Ala Ile Lys Asn Leu Leu Lys Ala Val Ser
                  80                  85                  90

 Lys Glu Met Ser Lys Arg Ser Pro
                  95

<210> 1159
<211> 2324
<212> DNA
<213> Homo sapien

<400> 1159
 ctccctttgg gcaaggacct gagacccttg tgctaagtca agaggctcaa 50

 tgggctgcag aagaactaga gaaggaccaa gcaaagccat gatatttcca 100

 tggaaatgtc agagcaccca gagggactta tggaacatct tcaagttgtg 150

 ggggtggaca atgctctgtt gtgatttcct ggcacatcat ggaaccgact 200

 gctggactta ccattattct gaaaaaccca tgaactggca aagggctaga 250

 agattctgcc gagacaatta cacagattta gttgccatac aaaacaaggc 300

 ggaaattgag tatctggaga agactctgcc tttcagtcgt tcttactact 350

 ggataggaat ccggaagata ggaggaatat ggacgtgggt gggaaccaac 400

 aaatctctta ctgaagaagc agagaactgg ggagatggtg agcccaacaa 450

 caagaagaac aaggaggact gcgtggagat ctatatcaag agaaacaaag 500

 atgcaggcaa atggaacgat gacgcctgcc acaaactaaa ggcagccctc 550

 tgttacacag cttcttgcca gccctggtca tgcagtggcc atggagaatg 600

 tgtagaaatc atcaataatt acacctgcaa ctgtgatgtg gggtactatg 650

 ggccccagtg tcagtttgtg attcagtgtg agcctttgga ggccccagag 700

 ctgggtacca tggactgtac tcaccctttg ggaaacttca gcttcagctc 750

 acagtgtgcc ttcagctgct ctgaaggaac aaacttaact gggattgaag 800

 aaaccacctg tggaccattt ggaaactggt catctccaga accaacctgt 850

 caagtgattc agtgtgagcc tctatcagca ccagatttgg ggatcatgaa 900

 ctgtagccat cccctggcca gcttcagctt tacctctgca tgtaccttca 950

 tctgctcaga aggaactgag ttaattggga agaagaaaac catttgtgaa 1000

 tcatctggaa tctggtcaaa tcctagtcca atatgtcaaa aattggacaa 1050

 aagtttctca atgattaagg agggtgatta taaccccctc ttcattccag 1100

 tggcagtcat ggttactgca ttctctgggt tggcatttat catttggctg 1150

 gcaaggagat taaaaaaagg caagaaatcc aagagaagta tgaatgaccc 1200

 atattaaatc gcccttggtg aaagaaaatt cttggaatac taaaaatcat 1250

 gagatccttt aaatccttcc atgaaacgtt ttgtgtggtg gcacctccta 1300

 cgtcaaacat gaagtgtgtt tccttcagtg catctgggaa gatttctacc 1350

 tgaccaacag ttccttcagc ttccatttcg cccctcattt atccctcaac 1400

 ccccagccca caggtgttta tacagctcag ctttttgtct tttctgagga 1450

 gaaacaaata agaccataaa gggaaaggat tcatgtggaa tataaagatg 1500

 gctgactttg ctctttcttg actcttgttt tcagtttcaa ttcagtgctg 1550

 tacttgatga cagacacttc taaatgaagt gcaaatttga tacatatgtg 1600

 aatatggact cagttttctt gcagatcaaa tttcacgtcg tcttctgtat 1650

 actgtggagg tacactctta tagaaagttc aaaaagtcta cgctctcctt 1700

 tctttctaac tccagtgaag taatggggtc ctgctcaagt tgaaagagtc 1750

 ctatttgcac tgtagcctcg ccgtctgtga attggaccat cctatttaac 1800

 tggcttcagc ctccccacct tcttcagcca cctctctttt tcagttggct 1850

 gacttccaca cctagcatct catgagtgcc aagcaaaagg agagaagaga 1900

 gaaatagcct gcgctgtttt ttagtttggg ggttttgctg tttcctttta 1950

 tgagacccat tcctatttct tatagtcaat gtttctttta tcacgatatt 2000

 attagtaaga aaacatcact gaaatgctag ctgcaagtga catctctttg 2050

 atgtcatatg gaagagttaa aacaggtgga gaaattcctt gattcacaat 2100

 gaaatgctct cctttcccct gcccccagac cttttatcca cttacctaga 2150

 ttctacatat tctttaaatt tcatctcagg cctccctcaa ccccaccact 2200

 tcttttataa ctagtccttt actaatccaa cccatgatga gctcctcttc 2250

 ctggcttctt actgaaaggt taccctgtaa catgcaattt tgcatttgaa 2300

 taaagcctgc tttttaagtg ttaa 2324

<210> 1160
<211> 372
<212> PRT
<213> Homo sapien

<400> 1160
 Met Ile Phe Pro Trp Lys Cys Gln Ser Thr Gln Arg Asp Leu Trp
   1               5                  10                  15

 Asn Ile Phe Lys Leu Trp Gly Trp Thr Met Leu Cys Cys Asp Phe
                  20                  25                  30

 Leu Ala His His Gly Thr Asp Cys Trp Thr Tyr His Tyr Ser Glu
                  35                  40                  45

 Lys Pro Met Asn Trp Gln Arg Ala Arg Arg Phe Cys Arg Asp Asn
                  50                  55                  60

 Tyr Thr Asp Leu Val Ala Ile Gln Asn Lys Ala Glu Ile Glu Tyr
                  65                  70                  75

 Leu Glu Lys Thr Leu Pro Phe Ser Arg Ser Tyr Tyr Trp Ile Gly
                  80                  85                  90

 Ile Arg Lys Ile Gly Gly Ile Trp Thr Trp Val Gly Thr Asn Lys
                  95                 100                 105

 Ser Leu Thr Glu Glu Ala Glu Asn Trp Gly Asp Gly Glu Pro Asn
                 110                 115                 120

 Asn Lys Lys Asn Lys Glu Asp Cys Val Glu Ile Tyr Ile Lys Arg
                 125                 130                 135

 Asn Lys Asp Ala Gly Lys Trp Asn Asp Asp Ala Cys His Lys Leu
                 140                 145                 150

 Lys Ala Ala Leu Cys Tyr Thr Ala Ser Cys Gln Pro Trp Ser Cys
                 155                 160                 165

 Ser Gly His Gly Glu Cys Val Glu Ile Ile Asn Asn Tyr Thr Cys
                 170                 175                 180

 Asn Cys Asp Val Gly Tyr Tyr Gly Pro Gln Cys Gln Phe Val Ile
                 185                 190                 195

 Gln Cys Glu Pro Leu Glu Ala Pro Glu Leu Gly Thr Met Asp Cys
                 200                 205                 210

 Thr His Pro Leu Gly Asn Phe Ser Phe Ser Ser Gln Cys Ala Phe
                 215                 220                 225

 Ser Cys Ser Glu Gly Thr Asn Leu Thr Gly Ile Glu Glu Thr Thr
                 230                 235                 240

 Cys Gly Pro Phe Gly Asn Trp Ser Ser Pro Glu Pro Thr Cys Gln
                 245                 250                 255

 Val Ile Gln Cys Glu Pro Leu Ser Ala Pro Asp Leu Gly Ile Met
                 260                 265                 270

 Asn Cys Ser His Pro Leu Ala Ser Phe Ser Phe Thr Ser Ala Cys
                 275                 280                 285

 Thr Phe Ile Cys Ser Glu Gly Thr Glu Leu Ile Gly Lys Lys Lys
                 290                 295                 300

 Thr Ile Cys Glu Ser Ser Gly Ile Trp Ser Asn Pro Ser Pro Ile
                 305                 310                 315

 Cys Gln Lys Leu Asp Lys Ser Phe Ser Met Ile Lys Glu Gly Asp
                 320                 325                 330

 Tyr Asn Pro Leu Phe Ile Pro Val Ala Val Met Val Thr Ala Phe
                 335                 340                 345

 Ser Gly Leu Ala Phe Ile Ile Trp Leu Ala Arg Arg Leu Lys Lys
                 350                 355                 360

 Gly Lys Lys Ser Lys Arg Ser Met Asn Asp Pro Tyr
                 365                 370

<210> 1161
<211> 2930
<212> DNA
<213> Homo sapien

<400> 1161
 gaattccggt ttcttcctaa aaaatgtctg atggccgctt tctcggtcgg 50

 caccgccatg aatgccagca gttactctgc agagatgacg gagcccaagt 100

 cggtgtgtgt ctcggtggat gaggtggtgt ccagcaacat ggaggccact 150

 gagacggacc tgctgaatgg acatctgaaa aaagtagata ataacctcac 200

 ggaagcccag cgcttctcct ccttgcctcg gagggcagct gtgaacattg 250

 aattcaggga cctttcctat tcggttcctg aaggaccctg gtggaggaag 300

 aaaggataca agaccctcct gaaaggaatt tccgggaagt tcaatagtgg 350

 tgagttggtg gccattatgg gtccttccgg ggccgggaag tccacgctga 400

 tgaacatcct ggctggatac agggagacgg gcatgaaggg ggccgtcctc 450

 atcaacggcc tgccccggga cctgcgctgc ttccggaagg tgtcctgcta 500

 catcatgcag gatgacatgc tgctgccgca tctcactgtg caggaggcca 550

 tgatggtgtc ggcacatctg aagcttcagg agaaggatga aggcagaagg 600

 gaaatggtca aggagatact gacagcgctg ggcttgctgt cttgcgccaa 650

 cacgcggacc gggagcctgt caggtggtca gcgcaagcgc ctggccatcg 700

 cgctggagct ggtgaacaac cctccagtca tgttcttcga tgagcccacc 750

 agcggcctgg acagcgcctc ctgcttccag gtggtctcgc tgatgaaagg 800

 gctcgctcaa gggggtcgct ccatcatttg caccatccac cagcccagcg 850

 ccaaactctt cgagctgttc gaccagcttt acgtcctgag tcaaggacaa 900

 tgtgtgtacc ggggaaaagt ctgcaatctt gtgccatatt tgagggattt 950

 gggtctgaac tgcccaacct accacaaccc agcagatttt gtcatggagg 1000

 ttgcatccgg cgagtacggt gatcagaaca gtcggctggt gagagcggtt 1050

 cgggagggca tgtgtgactc agaccacaag agagacctcg ggggtgatgc 1100

 cgaggtgaac ccttttcttt ggcaccgccc ctctgaagag gtaaagcaga 1150

 caaaacgatt aaaggggttg agaaaggact cctcgtccat ggaaggctgc 1200

 cacagcttct ctgccagctg cctcacgcag ttctgcatcc tcttcaagag 1250

 gaccttcctc agcatcatga gggactcggt cctgacacac ctgcgcatca 1300

 cctcgcacat tgggatcggc ctcctcattg gcctgctgta cttggggatc 1350

 gggaacgaaa ccaagaaggt cttgagcaac tccggcttcc tcttcttctc 1400

 catgctgttc ctcatgttcg cggccctcat gcctactgtt ctgacatttc 1450

 ccctggagat gggagtcttt cttcgggaac acctgaacta ctggtacagc 1500

 ctgaaggcct actacctggc caagaccatg gcagacgtgc cctttcagat 1550

 catgttccca gtggcctact gcagcatcgt gtactggatg acgtcgcagc 1600

 cgtccgacgc cgtgcgcttt gtgctgtttg ccgcgctggg caccatgacc 1650

 tccctggtgg cacagtccct gggcctgctg atcggagccg cctccacgtc 1700

 cctgcaggtg gccactttcg tgggcccagt gacagccatc ccggtgctcc 1750

 tgttctcggg gttcttcgtc agcttcgaca ccatccccac gtacctacag 1800

 tggatgtcct acatctccta tgtcaggtat gggttcgaag gggtcatcct 1850

 ctccatctat ggcttagacc gggaagatct gcactgtgac atcgacgaga 1900

 cgtgccactt ccagaagtcg gaggccatcc tgcgggagct ggacgtggaa 1950

 aatgccaagc tgtacctgga cttcatcgta ctcgggattt tcttcatctc 2000

 cctccgcctc attgcctatt tggtcctcag gtacaaaatc cgggcagaga 2050

 ggtaaaacac ctgaatgcca ggaaacagga agattagaca ctgtggccga 2100

 gggcacgtct agaatcgagg aggcaagcct gtgcccgacc gacgacacag 2150

 agactcttct gatccaaccc ctagaaccgc gttgggtttg tgggtgtctc 2200

 gtgctcagcc actctgccca gctgggttgg atcttctctc cattcccctt 2250

 tctagcttta actaggaaga tgtaggcaga ttggtggttt tttttttttt 2300

 tttaacatac agaattttaa ataccacaac tggggcagaa tttaaagctg 2350

 caacacagct ggtgatgaga ggcttcctca gtccagtcgc tccttagcac 2400

 caggcaccgt gggtcctgga tggggaactg caagcagcct ctcagctgat 2450

 ggctgcacag tcagatgtct ggtggcagag agtccgagca tggagcgatt 2500

 ccattttatg actgttgttt ttcacatttt catctttcta aggtgtgtct 2550

 cttttccaat gagaagtcat ttttgcaagc caaaagtcga tcaatcgcat 2600

 tcattttaag aaattatacc tttttagtac ttgctgaaga atgattcagg 2650

 gtaaatcaca tactttgttt agagaggcga ggggtttaac ccgagtcacc 2700

 cagctggtct catacataga cagcacttgt gaaggattga atgcaggttc 2750

 caggtggagg gaagacgtgg acaccatctc cactgagcca tgcagacatt 2800

 tttaaaagct atacacaaaa ttgtgagaag acattggcca actctttcaa 2850

 agtctttctt tttccacgtg cttcttattt taagcgaaat atattgtttg 2900

 tttcttccta aaaaaaaaaa aaaaaaaaaa 2930

<210> 1162
<211> 674
<212> PRT
<213> Homo sapien

<400> 1162
 Met Ala Ala Phe Ser Val Gly Thr Ala Met Asn Ala Ser Ser Tyr
   1               5                  10                  15

 Ser Ala Glu Met Thr Glu Pro Lys Ser Val Cys Val Ser Val Asp
                  20                  25                  30

 Glu Val Val Ser Ser Asn Met Glu Ala Thr Glu Thr Asp Leu Leu
                  35                  40                  45

 Asn Gly His Leu Lys Lys Val Asp Asn Asn Leu Thr Glu Ala Gln
                  50                  55                  60

 Arg Phe Ser Ser Leu Pro Arg Arg Ala Ala Val Asn Ile Glu Phe
                  65                  70                  75

 Arg Asp Leu Ser Tyr Ser Val Pro Glu Gly Pro Trp Trp Arg Lys
                  80                  85                  90

 Lys Gly Tyr Lys Thr Leu Leu Lys Gly Ile Ser Gly Lys Phe Asn
                  95                 100                 105

 Ser Gly Glu Leu Val Ala Ile Met Gly Pro Ser Gly Ala Gly Lys
                 110                 115                 120

 Ser Thr Leu Met Asn Ile Leu Ala Gly Tyr Arg Glu Thr Gly Met
                 125                 130                 135

 Lys Gly Ala Val Leu Ile Asn Gly Leu Pro Arg Asp Leu Arg Cys
                 140                 145                 150

 Phe Arg Lys Val Ser Cys Tyr Ile Met Gln Asp Asp Met Leu Leu
                 155                 160                 165

 Pro His Leu Thr Val Gln Glu Ala Met Met Val Ser Ala His Leu
                 170                 175                 180

 Lys Leu Gln Glu Lys Asp Glu Gly Arg Arg Glu Met Val Lys Glu
                 185                 190                 195

 Ile Leu Thr Ala Leu Gly Leu Leu Ser Cys Ala Asn Thr Arg Thr
                 200                 205                 210

 Gly Ser Leu Ser Gly Gly Gln Arg Lys Arg Leu Ala Ile Ala Leu
                 215                 220                 225

 Glu Leu Val Asn Asn Pro Pro Val Met Phe Phe Asp Glu Pro Thr
                 230                 235                 240

 Ser Gly Leu Asp Ser Ala Ser Cys Phe Gln Val Val Ser Leu Met
                 245                 250                 255

 Lys Gly Leu Ala Gln Gly Gly Arg Ser Ile Ile Cys Thr Ile His
                 260                 265                 270

 Gln Pro Ser Ala Lys Leu Phe Glu Leu Phe Asp Gln Leu Tyr Val
                 275                 280                 285

 Leu Ser Gln Gly Gln Cys Val Tyr Arg Gly Lys Val Cys Asn Leu
                 290                 295                 300

 Val Pro Tyr Leu Arg Asp Leu Gly Leu Asn Cys Pro Thr Tyr His
                 305                 310                 315

 Asn Pro Ala Asp Phe Val Met Glu Val Ala Ser Gly Glu Tyr Gly
                 320                 325                 330

 Asp Gln Asn Ser Arg Leu Val Arg Ala Val Arg Glu Gly Met Cys
                 335                 340                 345

 Asp Ser Asp His Lys Arg Asp Leu Gly Gly Asp Ala Glu Val Asn
                 350                 355                 360

 Pro Phe Leu Trp His Arg Pro Ser Glu Glu Val Lys Gln Thr Lys
                 365                 370                 375

 Arg Leu Lys Gly Leu Arg Lys Asp Ser Ser Ser Met Glu Gly Cys
                 380                 385                 390

 His Ser Phe Ser Ala Ser Cys Leu Thr Gln Phe Cys Ile Leu Phe
                 395                 400                 405

 Lys Arg Thr Phe Leu Ser Ile Met Arg Asp Ser Val Leu Thr His
                 410                 415                 420

 Leu Arg Ile Thr Ser His Ile Gly Ile Gly Leu Leu Ile Gly Leu
                 425                 430                 435

 Leu Tyr Leu Gly Ile Gly Asn Glu Thr Lys Lys Val Leu Ser Asn
                 440                 445                 450

 Ser Gly Phe Leu Phe Phe Ser Met Leu Phe Leu Met Phe Ala Ala
                 455                 460                 465

 Leu Met Pro Thr Val Leu Thr Phe Pro Leu Glu Met Gly Val Phe
                 470                 475                 480

 Leu Arg Glu His Leu Asn Tyr Trp Tyr Ser Leu Lys Ala Tyr Tyr
                 485                 490                 495

 Leu Ala Lys Thr Met Ala Asp Val Pro Phe Gln Ile Met Phe Pro
                 500                 505                 510

 Val Ala Tyr Cys Ser Ile Val Tyr Trp Met Thr Ser Gln Pro Ser
                 515                 520                 525

 Asp Ala Val Arg Phe Val Leu Phe Ala Ala Leu Gly Thr Met Thr
                 530                 535                 540

 Ser Leu Val Ala Gln Ser Leu Gly Leu Leu Ile Gly Ala Ala Ser
                 545                 550                 555

 Thr Ser Leu Gln Val Ala Thr Phe Val Gly Pro Val Thr Ala Ile
                 560                 565                 570

 Pro Val Leu Leu Phe Ser Gly Phe Phe Val Ser Phe Asp Thr Ile
                 575                 580                 585

 Pro Thr Tyr Leu Gln Trp Met Ser Tyr Ile Ser Tyr Val Arg Tyr
                 590                 595                 600

 Gly Phe Glu Gly Val Ile Leu Ser Ile Tyr Gly Leu Asp Arg Glu
                 605                 610                 615

 Asp Leu His Cys Asp Ile Asp Glu Thr Cys His Phe Gln Lys Ser
                 620                 625                 630

 Glu Ala Ile Leu Arg Glu Leu Asp Val Glu Asn Ala Lys Leu Tyr
                 635                 640                 645

 Leu Asp Phe Ile Val Leu Gly Ile Phe Phe Ile Ser Leu Arg Leu
                 650                 655                 660

 Ile Ala Tyr Leu Val Leu Arg Tyr Lys Ile Arg Ala Glu Arg
                 665                 670

<210> 1163
<211> 911
<212> DNA
<213> Homo sapien

<400> 1163
 cccacgcgtc cggtcagagc tggagggccg ggcaccgcgg ccatggaggg 50

 tcaacgctgg ctgccgctgg aggccaatcc cgaggtcacc aaccagtttc 100

 ttaaacaatt aggtctacat cctaactggc aattcgttga tgtatatgga 150

 atggatcctg aactccttag catggtacca agaccagtct gtgcagtctt 200

 acttctcttt cctattacag aaaagtatga agtattcaga acagaagagg 250

 aagaaaaaat aaaatctcag ggacaagatg ttacatcatc agtatatttc 300

 atgaagcaaa caatcagcaa tgcctgtgga acaattggac tgattcatgc 350

 tattgcaaac aataaagaca agatgcactt tgaatctgga tcaaccttga 400

 aaaaattcct ggaggaatct gtgtcaatga gccctgaaga acgagccaga 450

 tacctggaga actatgatgc catccgagtt actcatgaga ccagtgccca 500

 tgaaggtcag actgaggcac caagtataga tgagaaagta gatcttcatt 550

 ttattgcatt agttcatgta gatgggcatc tctatgaatt agatgggcgg 600

 aagccatttc caattaacca tggtgaaact agtgatgaaa ctttattaga 650

 ggatgccata gaagtttgca agaagtttat ggagcgcgac cctgatgaac 700

 taagatttaa tgcgattgct ctttctgcag catagcttgt caataatgga 750

 aacaccaaaa actgtattat ttgcaactaa attttctctg ccatacacta 800

 actcaaaaat tttgatattt tcattaactt gatgattaaa ctttatgtga 850

 gttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 900

 aaaaaaaaaa a 911

<210> 1164
<211> 230
<212> PRT
<213> Homo sapien

<400> 1164
 Met Glu Gly Gln Arg Trp Leu Pro Leu Glu Ala Asn Pro Glu Val
   1               5                  10                  15

 Thr Asn Gln Phe Leu Lys Gln Leu Gly Leu His Pro Asn Trp Gln
                  20                  25                  30

 Phe Val Asp Val Tyr Gly Met Asp Pro Glu Leu Leu Ser Met Val
                  35                  40                  45

 Pro Arg Pro Val Cys Ala Val Leu Leu Leu Phe Pro Ile Thr Glu
                  50                  55                  60

 Lys Tyr Glu Val Phe Arg Thr Glu Glu Glu Glu Lys Ile Lys Ser
                  65                  70                  75

 Gln Gly Gln Asp Val Thr Ser Ser Val Tyr Phe Met Lys Gln Thr
                  80                  85                  90

 Ile Ser Asn Ala Cys Gly Thr Ile Gly Leu Ile His Ala Ile Ala
                  95                 100                 105

 Asn Asn Lys Asp Lys Met His Phe Glu Ser Gly Ser Thr Leu Lys
                 110                 115                 120

 Lys Phe Leu Glu Glu Ser Val Ser Met Ser Pro Glu Glu Arg Ala
                 125                 130                 135

 Arg Tyr Leu Glu Asn Tyr Asp Ala Ile Arg Val Thr His Glu Thr
                 140                 145                 150

 Ser Ala His Glu Gly Gln Thr Glu Ala Pro Ser Ile Asp Glu Lys
                 155                 160                 165

 Val Asp Leu His Phe Ile Ala Leu Val His Val Asp Gly His Leu
                 170                 175                 180

 Tyr Glu Leu Asp Gly Arg Lys Pro Phe Pro Ile Asn His Gly Glu
                 185                 190                 195

 Thr Ser Asp Glu Thr Leu Leu Glu Asp Ala Ile Glu Val Cys Lys
                 200                 205                 210

 Lys Phe Met Glu Arg Asp Pro Asp Glu Leu Arg Phe Asn Ala Ile
                 215                 220                 225

 Ala Leu Ser Ala Ala
                 230

<210> 1165
<211> 3447
<212> DNA
<213> Homo sapien

<400> 1165
 ggccagtccg cccggcggct cgcgcacggc tccgcggtcc cttttgcctg 50

 tccagccggc cgcctgtccc tgctccctcc ctccgtgagg tgtccgggtt 100

 cccttcgccc agctctccca cccctacccg accccggcgc ccgggctccc 150

 agagggaact gcacttcggc agagttgaat gaatgaagag agacgcggag 200

 aactcctaag gaggagattg gacaggctgg actccccatt gcttttctaa 250

 aaatcttgga aactttgtcc ttcattgaat tacgacactg tccaccttta 300

 atttcctcga aaacgcctgt aactcggctg aagccatgcc ttgtgttcag 350

 gcgcagtatg ggtcctcgcc tcaaggagcc agccccgctt ctcagagcta 400

 cagttaccac tcttcgggag aatacagctc cgatttctta actccagagt 450

 ttgtcaagtt tagcatggac ctcaccaaca ctgaaatcac tgccaccact 500

 tctctcccca gcttcagtac ctttatggac aactacagca caggctacga 550

 cgtcaagcca ccttgcttgt accaaatgcc cctgtccgga cagcagtcct 600

 ccattaaggt agaagacatt cagatgcaca actaccagca acacagccac 650

 ctgccccccc agtctgagga gatgatgccg cactccgggt cggtttacta 700

 caagccctcc tcgcccccga cgcccaccac cccgggcttc caggtgcagc 750

 acagccccat gtgggacgac ccgggatctc tccacaactt ccaccagaac 800

 tacgtggcca ctacgcacat gatcgagcag aggaaaacgc cagtctcccg 850

 cctctccctc ttctccttta agcaatcgcc ccctggcacc ccggtgtcta 900

 gttgccagat gcgcttcgac gggcccctgc acgtccccat gaacccggag 950

 cccgccggca gccaccacgt ggtggacggg cagaccttcg ctgtgcccaa 1000

 ccccattcgc aagcccgcgt ccatgggctt cccgggcctg cagatcggcc 1050

 acgcgtctca gctgctcgac acgcaggtgc cctcaccgcc gtcgcggggc 1100

 tccccctcca acgaggggct gtgcgctgtg tgtggggaca acgcggcctg 1150

 ccaacactac ggcgtgcgca cctgtgaggg ctgcaaaggc ttctttaagc 1200

 gcacagtgca aaaaaatgca aaatacgtgt gtttagcaaa taaaaactgc 1250

 ccagtggaca agcgtcgccg gaatcgctgt cagtactgcc gatttcagaa 1300

 gtgcctggct gttgggatgg tcaaagaagt ggttcgcaca gacagtttaa 1350

 aaggccggag aggtcgtttg ccctcgaaac cgaagagccc acaggagccc 1400

 tctccccctt cgcccccggt gagtctgatc agtgccctcg tcagggccca 1450

 tgtcgactcc aacccggcta tgaccagcct ggactattcc aggttccagg 1500

 cgaaccctga ctatcaaatg agtggagatg acacccagca tatccagcaa 1550

 ttctatgatc tcctgactgg ctccatggag atcatccggg gctgggcaga 1600

 gaagatccct ggcttcgcag acctgcccaa agccgaccaa gacctgcttt 1650

 ttgaatcagc tttcttagaa ctgtttgtcc ttcgattagc atacaggtcc 1700

 aacccagtgg agggtaaact catcttttgc aatggggtgg tcttgcacag 1750

 gttgcaatgc gttcgtggct ttggggaatg gattgattcc attgttgaat 1800

 tctcctccaa cttgcagaat atgaacatcg acatttctgc cttctcctgc 1850

 attgctgccc tggctatggt cacagagaga cacgggctca aggaacccaa 1900

 gagagtggaa gaactgcaaa acaagattgt aaattgtctc aaagaccacg 1950

 tgactttcaa caatgggggg ttgaaccgcc ccaattattt gtccaaactg 2000

 ttggggaagc tcccagaact tcgtaccctt tgcacacagg ggctacagcg 2050

 cattttctac ctgaaattgg aagacttggt gccaccgcca gcaataattg 2100

 acaaactttt cctggacact ttacctttct aagacctcct cccaagcact 2150

 tcaaaggaac tggaatgata atggaaactg tcaagagggg gcaagtcaca 2200

 tgggcagaga tagccgtgtg agcagtctca gctcaagctg ccccccattt 2250

 ctgtaaccct cctagccccc ttgatcccta aagaaaacaa acaaacaaac 2300

 aaaaactgtt gctatttcct aacctgcagg cagaacctga aagggcattt 2350

 tggctccggg gcatcctgga tttagaacat ggactacaca caatacagtg 2400

 gtataaactt tttattctca gtttaaaaat cagtttgttg ttcagaagaa 2450

 agattgctat aatgtataat gggaaatgtt tggccatgct tggttgttgc 2500

 agttcagaca aatgtaacac acacacacat acacacacac acacacacac 2550

 agagacacat cttaagggga cccacaagta ttgcccttta acaagacttc 2600

 aaagttttct gctgtaaaga aagctgtaat atatagtaaa actaaatgtt 2650

 gcgtgggtgg catgagttga agaaggcaaa ggcttgtaaa tttacccaat 2700

 gcagtttggc tttttaaatt attttgtgcc tatttatgaa taaatattac 2750

 aaattctaaa agataagtgt gtttgcaaaa aaaaagaaaa taaatacata 2800

 aaaaagggac aagcatgttg attctaggtt gaaaatgtta taggcacttg 2850

 ctacttcagt aatgtctata ttatataaat agtatttcag acactatgta 2900

 gtctgttaga ttttataaag attggtagtt atctgagctt aaacattttc 2950

 tcaattgtaa aataggtggg cacaagtatt acacatcaga aaatcctgac 3000

 aaaagggaca catagtgttt gtaacaccgt ccaacattcc ttgtttgtaa 3050

 gtgttgtatg taccgttgat gttgataaaa agaaagttta tatcttgatt 3100

 attttgttgt ctaaagctaa acaaaacttg catgcagcag cttttgactg 3150

 tttccagagt gcttataata tacataactc cctggaaata actgagcact 3200

 ttgaattttt tttatgtcta aaattgtcag ttaatttatt attttgtttg 3250

 agtaagaatt ttaatattgc catattctgt agtatttttc tttgtatatt 3300

 tctagtatgg cacatgatat gagtcactgc ctttttttct atggtgtatg 3350

 acagttagag atgctgattt tttttctgat aaattctttc tttgagaaag 3400

 acaattttaa tgtttacaac aataaaccat gtaaatgaaa aaaaaaa 3447

<210> 1166
<211> 598
<212> PRT
<213> Homo sapien

<400> 1166
 Met Pro Cys Val Gln Ala Gln Tyr Gly Ser Ser Pro Gln Gly Ala
   1               5                  10                  15

 Ser Pro Ala Ser Gln Ser Tyr Ser Tyr His Ser Ser Gly Glu Tyr
                  20                  25                  30

 Ser Ser Asp Phe Leu Thr Pro Glu Phe Val Lys Phe Ser Met Asp
                  35                  40                  45

 Leu Thr Asn Thr Glu Ile Thr Ala Thr Thr Ser Leu Pro Ser Phe
                  50                  55                  60

 Ser Thr Phe Met Asp Asn Tyr Ser Thr Gly Tyr Asp Val Lys Pro
                  65                  70                  75

 Pro Cys Leu Tyr Gln Met Pro Leu Ser Gly Gln Gln Ser Ser Ile
                  80                  85                  90

 Lys Val Glu Asp Ile Gln Met His Asn Tyr Gln Gln His Ser His
                  95                 100                 105

 Leu Pro Pro Gln Ser Glu Glu Met Met Pro His Ser Gly Ser Val
                 110                 115                 120

 Tyr Tyr Lys Pro Ser Ser Pro Pro Thr Pro Thr Thr Pro Gly Phe
                 125                 130                 135

 Gln Val Gln His Ser Pro Met Trp Asp Asp Pro Gly Ser Leu His
                 140                 145                 150

 Asn Phe His Gln Asn Tyr Val Ala Thr Thr His Met Ile Glu Gln
                 155                 160                 165

 Arg Lys Thr Pro Val Ser Arg Leu Ser Leu Phe Ser Phe Lys Gln
                 170                 175                 180

 Ser Pro Pro Gly Thr Pro Val Ser Ser Cys Gln Met Arg Phe Asp
                 185                 190                 195

 Gly Pro Leu His Val Pro Met Asn Pro Glu Pro Ala Gly Ser His
                 200                 205                 210

 His Val Val Asp Gly Gln Thr Phe Ala Val Pro Asn Pro Ile Arg
                 215                 220                 225

 Lys Pro Ala Ser Met Gly Phe Pro Gly Leu Gln Ile Gly His Ala
                 230                 235                 240

 Ser Gln Leu Leu Asp Thr Gln Val Pro Ser Pro Pro Ser Arg Gly
                 245                 250                 255

 Ser Pro Ser Asn Glu Gly Leu Cys Ala Val Cys Gly Asp Asn Ala
                 260                 265                 270

 Ala Cys Gln His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys Gly
                 275                 280                 285

 Phe Phe Lys Arg Thr Val Gln Lys Asn Ala Lys Tyr Val Cys Leu
                 290                 295                 300

 Ala Asn Lys Asn Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys
                 305                 310                 315

 Gln Tyr Cys Arg Phe Gln Lys Cys Leu Ala Val Gly Met Val Lys
                 320                 325                 330

 Glu Val Val Arg Thr Asp Ser Leu Lys Gly Arg Arg Gly Arg Leu
                 335                 340                 345

 Pro Ser Lys Pro Lys Ser Pro Gln Glu Pro Ser Pro Pro Ser Pro
                 350                 355                 360

 Pro Val Ser Leu Ile Ser Ala Leu Val Arg Ala His Val Asp Ser
                 365                 370                 375

 Asn Pro Ala Met Thr Ser Leu Asp Tyr Ser Arg Phe Gln Ala Asn
                 380                 385                 390

 Pro Asp Tyr Gln Met Ser Gly Asp Asp Thr Gln His Ile Gln Gln
                 395                 400                 405

 Phe Tyr Asp Leu Leu Thr Gly Ser Met Glu Ile Ile Arg Gly Trp
                 410                 415                 420

 Ala Glu Lys Ile Pro Gly Phe Ala Asp Leu Pro Lys Ala Asp Gln
                 425                 430                 435

 Asp Leu Leu Phe Glu Ser Ala Phe Leu Glu Leu Phe Val Leu Arg
                 440                 445                 450

 Leu Ala Tyr Arg Ser Asn Pro Val Glu Gly Lys Leu Ile Phe Cys
                 455                 460                 465

 Asn Gly Val Val Leu His Arg Leu Gln Cys Val Arg Gly Phe Gly
                 470                 475                 480

 Glu Trp Ile Asp Ser Ile Val Glu Phe Ser Ser Asn Leu Gln Asn
                 485                 490                 495

 Met Asn Ile Asp Ile Ser Ala Phe Ser Cys Ile Ala Ala Leu Ala
                 500                 505                 510

 Met Val Thr Glu Arg His Gly Leu Lys Glu Pro Lys Arg Val Glu
                 515                 520                 525

 Glu Leu Gln Asn Lys Ile Val Asn Cys Leu Lys Asp His Val Thr
                 530                 535                 540

 Phe Asn Asn Gly Gly Leu Asn Arg Pro Asn Tyr Leu Ser Lys Leu
                 545                 550                 555

 Leu Gly Lys Leu Pro Glu Leu Arg Thr Leu Cys Thr Gln Gly Leu
                 560                 565                 570

 Gln Arg Ile Phe Tyr Leu Lys Leu Glu Asp Leu Val Pro Pro Pro
                 575                 580                 585

 Ala Ile Ile Asp Lys Leu Phe Leu Asp Thr Leu Pro Phe
                 590                 595

<210> 1167
<211> 3269
<212> DNA
<213> Homo sapien

<400> 1167
 ggccagtccg cccggcggct cgcgcacggc tccgcggtcc cttttgcctg 50

 tccagccggc cgcctgtccc tgctccctcc ctccgtgagg tgtccgggtt 100

 cccttcgccc agctctccca cccctacccg accccggcgc ccgggctccc 150

 agagggaact gcacttcggc agagttgaat gaatgaagac agacgcggag 200

 aactcctaag gaggagattg gacaggctgg actccccatt gcttttctaa 250

 aaatcttgga aactttgtcc ttcattgaat tacgacactg tccaccttta 300

 atttcctcga aaacgcctgt aactcggctg aagcttcagt acctttatgg 350

 acaactacag cacaggctac gacgtcaagc caccttgctt gtaccaaatg 400

 cccctgtccg gacagcagtc ctccattaag gtagaagaca ttcagatgca 450

 caactaccag caacacagcc acctgccccc ccagtctgag gagatgatgc 500

 cgcactccgg gtcggtttac tacaagccct cctcgccccc gacgcccacc 550

 accccgggct tccaggtgca gcacagcccc atgtgggacg acccgggatc 600

 tctccacaac ttccaccaga actacgtggc cactacgcac atgatcgagc 650

 agaggaaaac gccagtctcc cgcctctccc tcttctcctt taagcaatcg 700

 ccccctggca ccccggtgtc tagttgccag atgcgcttcg acgggcccct 750

 gcacgtcccc atgaacccgg agcccgccgg cagccaccac gtggtggacg 800

 ggcagacctt cgctgtgccc aaccccattc gcaagcccgc gtccatgggc 850

 ttcccgggcc tgcagatcgg ccacgcgtct cagctgctcg acacgcaggt 900

 gccctcaccg ccgtcgcggg gctccccctc caacgagggg ctgtgcgctg 950

 tgtgtgggga caacgcggcc tgccaacact acggcgtgcg cacctgtgag 1000

 ggctgcaaag gcttctttaa gcgcacagtg caaaaaaatg caaaatacgt 1050

 gtgtttagca aataaaaact gcccagtgga caagcgtcgc cggaatcgct 1100

 gtcagtactg ccgatttcag aagtgcctgg ctgttgggat ggtcaaagaa 1150

 gtggttcgca cagacagttt aaaaggccgg agaggtcgtt tgccctcgaa 1200

 accgaagagc ccacaggagc cctctccccc ttcgcccccg gtgagtctga 1250

 tcagtgccct cgtcagggcc catgtcgact ccaacccggc tatgaccagc 1300

 ctggactatt ccaggttcca ggcgaaccct gactatcaaa tgagtggaga 1350

 tgacacccag catatccagc aattctatga tctcctgact ggctccatgg 1400

 agatcatccg gggctgggca gagaagatcc ctggcttcgc agacctgccc 1450

 aaagccgacc aagacctgct ttttgaatca gctttcttag aactgtttgt 1500

 ccttcgatta gcatacaggt ccaacccagt ggagggtaaa ctcatctttt 1550

 gcaatggggt ggtcttgcac aggttgcaat gcgttcgtgg ctttggggaa 1600

 tggattgatt ccattgttga attctcctcc aacttgcaga atatgaacat 1650

 cgacatttct gccttctcct gcattgctgc cctggctatg gtcacagaga 1700

 gacacgggct caaggaaccc aagagagtgg aagaactgca aaacaagatt 1750

 gtaaattgtc tcaaagacca cgtgactttc aacaatgggg ggttgaaccg 1800

 ccccaattat ttgtccaaac tgttggggaa gctcccagaa cttcgtaccc 1850

 tttgcacaca ggggctacag cgcattttct acctgaaatt ggaagacttg 1900

 gtgccaccgc cagcaataat tgacaaactt ttcctggaca ctttaccttt 1950

 ctaagacctc ctcccaagca cttcaaagga actggaatga taatggaaac 2000

 tgtcaagagg gggcaagtca catgggcaga gatagccgtg tgagcagtct 2050

 cagctcaagc tgccccccat ttctgtaacc ctcctagccc ccttgatccc 2100

 taaagaaaac aaacaaacaa acaaaaactg ttgctatttc ctaacctgca 2150

 ggcagaacct gaaagggcat tttggctccg gggcatcctg gatttagaac 2200

 atggactaca cacaatacag tggtataaac tttttattct cagtttaaaa 2250

 atcagtttgt tgttcagaag aaagattgct ataatgtata atgggaaatg 2300

 tttggccatg cttggttgtt gcagttcaga caaatgtaac acacacacac 2350

 atacacacac acacacacac acagagacac atcttaaggg gacccacaag 2400

 tattgccctt taacaagact tcaaagtttt ctgctgtaaa gaaagctgta 2450

 atatatagta aaactaaatg ttgcgtgggt ggcatgagtt gaagaaggca 2500

 aaggcttgta aatttaccca atgcagtttg gctttttaaa ttattttgtg 2550

 cctatttatg aataaatatt acaaattcta aaagataagt gtgtttgcaa 2600

 aaaaaaagaa aataaataca taaaaaaggg acaagcatgt tgattctagg 2650

 ttgaaaatgt tataggcact tgctacttca gtaatgtcta tattatataa 2700

 atagtatttc agacactatg tagtctgtta gattttataa agattggtag 2750

 ttatctgagc ttaaacattt tctcaattgt aaaataggtg ggcacaagta 2800

 ttacacatca gaaaatcctg acaaaaggga cacatagtgt ttgtaacacc 2850

 gtccaacatt ccttgtttgt aagtgttgta tgtaccgttg atgttgataa 2900

 aaagaaagtt tatatcttga ttattttgtt gtctaaagct aaacaaaact 2950

 tgcatgcagc agcttttgac tgtttccaga gtgcttataa tatacataac 3000

 tccctggaaa taactgagca ctttgaattt tttttatgtc taaaattgtc 3050

 agttaattta ttattttgtt tgagtaagaa ttttaatatt gccatattct 3100

 gtagtatttt tctttgtata tttctagtat ggcacatgat atgagtcact 3150

 gccttttttt ctatggtgta tgacagttag agatgctgat tttttttctg 3200

 ataaattctt tctttgagaa agacaatttt aatgtttaca acaataaacc 3250

 atgtaaatga aaaaaaaaa 3269

<210> 1168
<211> 535
<212> PRT
<213> Homo sapien

<400> 1168
 Met Asp Asn Tyr Ser Thr Gly Tyr Asp Val Lys Pro Pro Cys Leu
   1               5                  10                  15

 Tyr Gln Met Pro Leu Ser Gly Gln Gln Ser Ser Ile Lys Val Glu
                  20                  25                  30

 Asp Ile Gln Met His Asn Tyr Gln Gln His Ser His Leu Pro Pro
                  35                  40                  45

 Gln Ser Glu Glu Met Met Pro His Ser Gly Ser Val Tyr Tyr Lys
                  50                  55                  60

 Pro Ser Ser Pro Pro Thr Pro Thr Thr Pro Gly Phe Gln Val Gln
                  65                  70                  75

 His Ser Pro Met Trp Asp Asp Pro Gly Ser Leu His Asn Phe His
                  80                  85                  90

 Gln Asn Tyr Val Ala Thr Thr His Met Ile Glu Gln Arg Lys Thr
                  95                 100                 105

 Pro Val Ser Arg Leu Ser Leu Phe Ser Phe Lys Gln Ser Pro Pro
                 110                 115                 120

 Gly Thr Pro Val Ser Ser Cys Gln Met Arg Phe Asp Gly Pro Leu
                 125                 130                 135

 His Val Pro Met Asn Pro Glu Pro Ala Gly Ser His His Val Val
                 140                 145                 150

 Asp Gly Gln Thr Phe Ala Val Pro Asn Pro Ile Arg Lys Pro Ala
                 155                 160                 165

 Ser Met Gly Phe Pro Gly Leu Gln Ile Gly His Ala Ser Gln Leu
                 170                 175                 180

 Leu Asp Thr Gln Val Pro Ser Pro Pro Ser Arg Gly Ser Pro Ser
                 185                 190                 195

 Asn Glu Gly Leu Cys Ala Val Cys Gly Asp Asn Ala Ala Cys Gln
                 200                 205                 210

 His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys Gly Phe Phe Lys
                 215                 220                 225

 Arg Thr Val Gln Lys Asn Ala Lys Tyr Val Cys Leu Ala Asn Lys
                 230                 235                 240

 Asn Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys Gln Tyr Cys
                 245                 250                 255

 Arg Phe Gln Lys Cys Leu Ala Val Gly Met Val Lys Glu Val Val
                 260                 265                 270

 Arg Thr Asp Ser Leu Lys Gly Arg Arg Gly Arg Leu Pro Ser Lys
                 275                 280                 285

 Pro Lys Ser Pro Gln Glu Pro Ser Pro Pro Ser Pro Pro Val Ser
                 290                 295                 300

 Leu Ile Ser Ala Leu Val Arg Ala His Val Asp Ser Asn Pro Ala
                 305                 310                 315

 Met Thr Ser Leu Asp Tyr Ser Arg Phe Gln Ala Asn Pro Asp Tyr
                 320                 325                 330

 Gln Met Ser Gly Asp Asp Thr Gln His Ile Gln Gln Phe Tyr Asp
                 335                 340                 345

 Leu Leu Thr Gly Ser Met Glu Ile Ile Arg Gly Trp Ala Glu Lys
                 350                 355                 360

 Ile Pro Gly Phe Ala Asp Leu Pro Lys Ala Asp Gln Asp Leu Leu
                 365                 370                 375

 Phe Glu Ser Ala Phe Leu Glu Leu Phe Val Leu Arg Leu Ala Tyr
                 380                 385                 390

 Arg Ser Asn Pro Val Glu Gly Lys Leu Ile Phe Cys Asn Gly Val
                 395                 400                 405

 Val Leu His Arg Leu Gln Cys Val Arg Gly Phe Gly Glu Trp Ile
                 410                 415                 420

 Asp Ser Ile Val Glu Phe Ser Ser Asn Leu Gln Asn Met Asn Ile
                 425                 430                 435

 Asp Ile Ser Ala Phe Ser Cys Ile Ala Ala Leu Ala Met Val Thr
                 440                 445                 450

 Glu Arg His Gly Leu Lys Glu Pro Lys Arg Val Glu Glu Leu Gln
                 455                 460                 465

 Asn Lys Ile Val Asn Cys Leu Lys Asp His Val Thr Phe Asn Asn
                 470                 475                 480

 Gly Gly Leu Asn Arg Pro Asn Tyr Leu Ser Lys Leu Leu Gly Lys
                 485                 490                 495

 Leu Pro Glu Leu Arg Thr Leu Cys Thr Gln Gly Leu Gln Arg Ile
                 500                 505                 510

 Phe Tyr Leu Lys Leu Glu Asp Leu Val Pro Pro Pro Ala Ile Ile
                 515                 520                 525

 Asp Lys Leu Phe Leu Asp Thr Leu Pro Phe
                 530                 535

<210> 1169
<211> 1413
<212> DNA
<213> Homo sapien

<400> 1169
 agggaataaa ggctcaggga ccggcagttc tactctagag cccaccagcc 50

 tctcagagcc tccggtgact ggcctgtgtc tccccctgga tggacatgtg 100

 gacggcgctg ctcatcctgc aagccttgtt gctaccctcc ctggctgatg 150

 gtgccacccc tgccctgcgc tttgtagccg tgggtgactg gggaggggtc 200

 cccaatgccc cattccacac ggcccgggaa atggccaatg ccaaggagat 250

 cgctcggact gtgcagatcc tgggtgcaga cttcatcctg tctctagggg 300

 acaattttta cttcactggt gtgcaagaca tcaatgacaa gaggttccag 350

 gagacctttg aggacgtatt ctctgaccgc tcccttcgca aagtgccctg 400

 gtacgtgcta gccggaaacc atgaccacct tggcaatgtc tctgcccaga 450

 ttgcatactc taagatctcc aagcgctgga acttccccag ccctttctac 500

 cgcctgcact tcaagatccc acagaccaat gtgtctgtgg ccatttttat 550

 gctggacaca gtgacactat gtggcaactc agatgacttc ctcagccagc 600

 agcctgagag gccccgagac gtgaagctgg cccgcacaca gctgtcctgg 650

 ctcaagaaac agctggcggc ggccagggag gactacgtgc tggtggctgg 700

 ccactacccc gtgtggtcca tagccgagca cgggcctacc cactgcctgg 750

 tcaagcagct acggccactg ctggccacat acggggtcac tgcctacctg 800

 tgcggccacg atcacaatct gcagtacctg caagatgaga atggcgtggg 850

 ctacgtgctg agtggggctg ggaatttcat ggacccctca aagcggcacc 900

 agcgcaaggt ccccaacggc tatctgcgct tccactatgg gactgaagac 950

 tcactgggtg gctttgccta tgtggagatc agctccaaag agatgactgt 1000

 cacttacatc gaggcctcgg gcaagtccct ctttaagacc aggctgccga 1050

 ggcgagccag gccctgaact cccatgactg cccagctctg aggcccgatc 1100

 tccactgttg ggtgggtggc ctgccgggac cctgctcaca ggcaggcttt 1150

 tcctccaacc tgtggcgctg cagcagggca ggaaggggaa acacagctga 1200

 tgaactgtgg tgccacatga cccttgtggc acagatgccc acgtatgtga 1250

 aacacacatg gacatgtgtc ccagccacag tgttatgctc tgtggctggc 1300

 tcacctttgc tgagttccgg ggtgcaatgg gggagggagg gagggaaagc 1350

 ttcctcctaa atcaagcatc tttctgttac tgatgttcaa taaaagaata 1400

 gttgccaagg ctg 1413

<210> 1170
<211> 325
<212> PRT
<213> Homo sapien

<400> 1170
 Met Asp Met Trp Thr Ala Leu Leu Ile Leu Gln Ala Leu Leu Leu
   1               5                  10                  15

 Pro Ser Leu Ala Asp Gly Ala Thr Pro Ala Leu Arg Phe Val Ala
                  20                  25                  30

 Val Gly Asp Trp Gly Gly Val Pro Asn Ala Pro Phe His Thr Ala
                  35                  40                  45

 Arg Glu Met Ala Asn Ala Lys Glu Ile Ala Arg Thr Val Gln Ile
                  50                  55                  60

 Leu Gly Ala Asp Phe Ile Leu Ser Leu Gly Asp Asn Phe Tyr Phe
                  65                  70                  75

 Thr Gly Val Gln Asp Ile Asn Asp Lys Arg Phe Gln Glu Thr Phe
                  80                  85                  90

 Glu Asp Val Phe Ser Asp Arg Ser Leu Arg Lys Val Pro Trp Tyr
                  95                 100                 105

 Val Leu Ala Gly Asn His Asp His Leu Gly Asn Val Ser Ala Gln
                 110                 115                 120

 Ile Ala Tyr Ser Lys Ile Ser Lys Arg Trp Asn Phe Pro Ser Pro
                 125                 130                 135

 Phe Tyr Arg Leu His Phe Lys Ile Pro Gln Thr Asn Val Ser Val
                 140                 145                 150

 Ala Ile Phe Met Leu Asp Thr Val Thr Leu Cys Gly Asn Ser Asp
                 155                 160                 165

 Asp Phe Leu Ser Gln Gln Pro Glu Arg Pro Arg Asp Val Lys Leu
                 170                 175                 180

 Ala Arg Thr Gln Leu Ser Trp Leu Lys Lys Gln Leu Ala Ala Ala
                 185                 190                 195

 Arg Glu Asp Tyr Val Leu Val Ala Gly His Tyr Pro Val Trp Ser
                 200                 205                 210

 Ile Ala Glu His Gly Pro Thr His Cys Leu Val Lys Gln Leu Arg
                 215                 220                 225

 Pro Leu Leu Ala Thr Tyr Gly Val Thr Ala Tyr Leu Cys Gly His
                 230                 235                 240

 Asp His Asn Leu Gln Tyr Leu Gln Asp Glu Asn Gly Val Gly Tyr
                 245                 250                 255

 Val Leu Ser Gly Ala Gly Asn Phe Met Asp Pro Ser Lys Arg His
                 260                 265                 270

 Gln Arg Lys Val Pro Asn Gly Tyr Leu Arg Phe His Tyr Gly Thr
                 275                 280                 285

 Glu Asp Ser Leu Gly Gly Phe Ala Tyr Val Glu Ile Ser Ser Lys
                 290                 295                 300

 Glu Met Thr Val Thr Tyr Ile Glu Ala Ser Gly Lys Ser Leu Phe
                 305                 310                 315

 Lys Thr Arg Leu Pro Arg Arg Ala Arg Pro
                 320                 325

<210> 1171
<211> 1497
<212> DNA
<213> Homo sapien

<400> 1171
 accgctggcc ccagggaaag ccgagcggcc accgagccgg cagagaccca 50

 ccgagcggcg gcggagggag cagcgccggg gcgcacgagg gcaccatggc 100

 ccagacgccc gccttcgaca agcccaaagt agaactgcat gtccacctag 150

 acggatccat caagcctgaa accatcttat actatggcag gaggagaggg 200

 atcgccctcc cagctaacac agcagagggg ctgctgaacg tcattggcat 250

 ggacaagccg ctcacccttc cagacttcct ggccaaattt gactactaca 300

 tgcctgctat cgcgggctgc cgggaggcta tcaaaaggat cgcctatgag 350

 tttgtagaga tgaaggccaa agagggcgtg gtgtatgtgg aggtgcggta 400

 cagtccgcac ctgctggcca actccaaagt ggagccaatc ccctggaacc 450

 aggctgaagg ggacctcacc ccagacgagg tggtggccct agtgggccag 500

 ggcctgcagg agggggagcg agacttcggg gtcaaggccc ggtccatcct 550

 gtgctgcatg cgccaccagc ccaactggtc ccccaaggtg gtggagctgt 600

 gtaagaacta ccagcagcag accgtggtag ccattgacct ggctggagat 650

 gagaccatcc caggaagcag cctcttgcct ggacatgtcc aggcctacca 700

 ggaggctgtg aagagcggca ttcaccgtac tgtccacgcc ggggaggtgg 750

 gctcggccga agtagtaaaa gaggctgtgg acatactcaa gacagagcgg 800

 ctgggacacg gctaccacac cctggaagac caggcccttt ataacaggct 850

 gcggcaggaa aacatgcact tcgagatctg cccctggtcc agctacctca 900

 ctggtgcctg gaagccggac acggagcatg cagtcattcg gctcaaaaat 950

 gaccaggcta actactcgct caacacagat gacccgctca tcttcaagtc 1000

 caccctggac actgattacc agatgaccaa acgggacatg ggctttactg 1050

 aagaggagtt taaaaggctg aacatcaatg cggccaaatc tagtttcctc 1100

 ccagaagatg aaaagaggga gcttctcgac ctgctctata aagcctatgg 1150

 gatgccacct tcagcctctg cagggcagaa cctctgaaga cgccactcct 1200

 ccaagccttc accctgtgga gtcaccccaa ctctgtgggg ctgagcaaca 1250

 tttttacatt tattccttcc aagaagacca tgatctcaat agtcagttac 1300

 tgatgctcct gaaccctatg tgtccatttc tgcacacacg tatacctcgg 1350

 catggccgcg tcacttctct gattatgtgc cctggcaggg accagcgccc 1400

 ttgcacatgg gcatggttga atctgaaacc ctccttctgt ggcaacttgt 1450

 actgaaaatc tggtgctcaa taaagaagcc catggctggt ggcatgc 1497

<210> 1172
<211> 363
<212> PRT
<213> Homo sapien

<400> 1172
 Met Ala Gln Thr Pro Ala Phe Asp Lys Pro Lys Val Glu Leu His
   1               5                  10                  15

 Val His Leu Asp Gly Ser Ile Lys Pro Glu Thr Ile Leu Tyr Tyr
                  20                  25                  30

 Gly Arg Arg Arg Gly Ile Ala Leu Pro Ala Asn Thr Ala Glu Gly
                  35                  40                  45

 Leu Leu Asn Val Ile Gly Met Asp Lys Pro Leu Thr Leu Pro Asp
                  50                  55                  60

 Phe Leu Ala Lys Phe Asp Tyr Tyr Met Pro Ala Ile Ala Gly Cys
                  65                  70                  75

 Arg Glu Ala Ile Lys Arg Ile Ala Tyr Glu Phe Val Glu Met Lys
                  80                  85                  90

 Ala Lys Glu Gly Val Val Tyr Val Glu Val Arg Tyr Ser Pro His
                  95                 100                 105

 Leu Leu Ala Asn Ser Lys Val Glu Pro Ile Pro Trp Asn Gln Ala
                 110                 115                 120

 Glu Gly Asp Leu Thr Pro Asp Glu Val Val Ala Leu Val Gly Gln
                 125                 130                 135

 Gly Leu Gln Glu Gly Glu Arg Asp Phe Gly Val Lys Ala Arg Ser
                 140                 145                 150

 Ile Leu Cys Cys Met Arg His Gln Pro Asn Trp Ser Pro Lys Val
                 155                 160                 165

 Val Glu Leu Cys Lys Asn Tyr Gln Gln Gln Thr Val Val Ala Ile
                 170                 175                 180

 Asp Leu Ala Gly Asp Glu Thr Ile Pro Gly Ser Ser Leu Leu Pro
                 185                 190                 195

 Gly His Val Gln Ala Tyr Gln Glu Ala Val Lys Ser Gly Ile His
                 200                 205                 210

 Arg Thr Val His Ala Gly Glu Val Gly Ser Ala Glu Val Val Lys
                 215                 220                 225

 Glu Ala Val Asp Ile Leu Lys Thr Glu Arg Leu Gly His Gly Tyr
                 230                 235                 240

 His Thr Leu Glu Asp Gln Ala Leu Tyr Asn Arg Leu Arg Gln Glu
                 245                 250                 255

 Asn Met His Phe Glu Ile Cys Pro Trp Ser Ser Tyr Leu Thr Gly
                 260                 265                 270

 Ala Trp Lys Pro Asp Thr Glu His Ala Val Ile Arg Leu Lys Asn
                 275                 280                 285

 Asp Gln Ala Asn Tyr Ser Leu Asn Thr Asp Asp Pro Leu Ile Phe
                 290                 295                 300

 Lys Ser Thr Leu Asp Thr Asp Tyr Gln Met Thr Lys Arg Asp Met
                 305                 310                 315

 Gly Phe Thr Glu Glu Glu Phe Lys Arg Leu Asn Ile Asn Ala Ala
                 320                 325                 330

 Lys Ser Ser Phe Leu Pro Glu Asp Glu Lys Arg Glu Leu Leu Asp
                 335                 340                 345

 Leu Leu Tyr Lys Ala Tyr Gly Met Pro Pro Ser Ala Ser Ala Gly
                 350                 355                 360

 Gln Asn Leu


<210> 1173
<211> 2119
<212> DNA
<213> Homo sapien

<400> 1173
 ggcacgagta ggggtggcgg gtcagtgctg ctcgggggct tctccatcca 50

 ggtccctgga gttcctggtc cctggagctc cgcacttggc gcgcaacctg 100

 cgtgaggcag cgcgactctg gcgactggcc ggccatgcct tcccgggctg 150

 aggactatga agtgttgtac accattggca caggctccta cggccgctgc 200

 cagaagatcc ggaggaagag tgatggcaag atattagttt ggaaagaact 250

 tgactatggc tccatgacag aagctgagaa acagatgctt gtttctgaag 300

 tgaatttgct tcgtgaactg aaacatccaa acatcgttcg ttactatgat 350

 cggattattg accggaccaa tacaacactg tacattgtaa tggaatattg 400

 tgaaggaggg gatctggcta gtgtaattac aaagggaacc aaggaaaggc 450

 aatacttaga tgaagagttt gttcttcgag tgatgactca gttgactctg 500

 gccctgaagg aatgccacag acgaagtgat ggtggtcata ccgtattgca 550

 tcgggatctt aaaccagcca atgttttcct ggatggcaag caaaacgtca 600

 agcttggaga ctttgggcta gctagaatat taaaccatga cacgagtttt 650

 gcaaaaacat ttgttggcac accttattac atgtctcctg aacaaatgaa 700

 tcgcatgtcc tacaatgaga aatcagatat ctggtcattg ggctgcttgc 750

 tgtatgagtt atgtgcatta atgcctccat ttacagcttt tagccagaaa 800

 gaactcgctg ggaaaatcag agaaggcaaa ttcaggcgaa ttccataccg 850

 ttactctgat gaattgaatg aaattattac gaggatgtta aacttaaagg 900

 attaccatcg accttctgtt gaagaaattc ttgagaaccc tttaatagca 950

 gatttggttg cagacgagca aagaagaaat cttgagagaa gagggcgaca 1000

 attaggagag ccagaaaaat cgcaggattc cagccctgta ttgagtgagc 1050

 tgaaactgaa ggaaattcag ttacaggagc gagagcgagc tctcaaagca 1100

 agagaagaaa gattggagca gaaagaacag gagctttgtg ttcgtgagag 1150

 actagcagag gacaaactgg ctagagcaga aaatctgttg aagaactaca 1200

 gcttgctaaa ggaacggaag ttcctgtctc tggcaagtaa tccagaactt 1250

 cttaatcttc catcctcagt aattaagaag aaagttcatt tcagtgggga 1300

 aagtaaagag aacatcatga ggagtgagaa ttctgagagt cagctcacat 1350

 ctaagtccaa gtgcaaggac ctgaagaaaa ggcttcacgc tgcccagctg 1400

 cgggctcaag ccctgtcaga tattgagaaa aattaccaac tgaaaagcag 1450

 acagatcctg ggcatgcgct agccaggtag agagacacag agctgtgtac 1500

 aggatgtaat attaccaacc tttaaagact gatattcaaa tgctgtagtg 1550

 ttgaatactt ggccccatga gccatgcctt tctgtatagt acacatgata 1600

 tttcggaatt ggttttactg ttcttcagca actattgtac aaaatgttca 1650

 catttaattt ttctttcttc ttttaagaac atattataaa aagaatactt 1700

 tcttggttgg gcttttaatc ctgtgtgtga ttactagtag gaacatgaga 1750

 tgtgacattc taaatcttgg gagaaaaaat aatattagga aaaaaatatt 1800

 tatgcaggaa gagtagcact cactgaatag ttttaaatga ctgagtggta 1850

 tgcttacaat tgtcatgtct agatttaaat tttaagtctg agattttaaa 1900

 tgtttttgag cttagaaaac ccagttagat gcaatttggt cattaatacc 1950

 atgacatctt gcttataaat attccattgc tctgtagttc aaatctgtta 2000

 gctttgtgaa aattcatcac tgtgatgttt gtattctttt tttttttctg 2050

 tttaacagaa tatgagctgt ctgtcattta cctacttctt tcccactaaa 2100

 taaaagaatt cttcagtta 2119

<210> 1174
<211> 445
<212> PRT
<213> Homo sapien

<400> 1174
 Met Pro Ser Arg Ala Glu Asp Tyr Glu Val Leu Tyr Thr Ile Gly
   1               5                  10                  15

 Thr Gly Ser Tyr Gly Arg Cys Gln Lys Ile Arg Arg Lys Ser Asp
                  20                  25                  30

 Gly Lys Ile Leu Val Trp Lys Glu Leu Asp Tyr Gly Ser Met Thr
                  35                  40                  45

 Glu Ala Glu Lys Gln Met Leu Val Ser Glu Val Asn Leu Leu Arg
                  50                  55                  60

 Glu Leu Lys His Pro Asn Ile Val Arg Tyr Tyr Asp Arg Ile Ile
                  65                  70                  75

 Asp Arg Thr Asn Thr Thr Leu Tyr Ile Val Met Glu Tyr Cys Glu
                  80                  85                  90

 Gly Gly Asp Leu Ala Ser Val Ile Thr Lys Gly Thr Lys Glu Arg
                  95                 100                 105

 Gln Tyr Leu Asp Glu Glu Phe Val Leu Arg Val Met Thr Gln Leu
                 110                 115                 120

 Thr Leu Ala Leu Lys Glu Cys His Arg Arg Ser Asp Gly Gly His
                 125                 130                 135

 Thr Val Leu His Arg Asp Leu Lys Pro Ala Asn Val Phe Leu Asp
                 140                 145                 150

 Gly Lys Gln Asn Val Lys Leu Gly Asp Phe Gly Leu Ala Arg Ile
                 155                 160                 165

 Leu Asn His Asp Thr Ser Phe Ala Lys Thr Phe Val Gly Thr Pro
                 170                 175                 180

 Tyr Tyr Met Ser Pro Glu Gln Met Asn Arg Met Ser Tyr Asn Glu
                 185                 190                 195

 Lys Ser Asp Ile Trp Ser Leu Gly Cys Leu Leu Tyr Glu Leu Cys
                 200                 205                 210

 Ala Leu Met Pro Pro Phe Thr Ala Phe Ser Gln Lys Glu Leu Ala
                 215                 220                 225

 Gly Lys Ile Arg Glu Gly Lys Phe Arg Arg Ile Pro Tyr Arg Tyr
                 230                 235                 240

 Ser Asp Glu Leu Asn Glu Ile Ile Thr Arg Met Leu Asn Leu Lys
                 245                 250                 255

 Asp Tyr His Arg Pro Ser Val Glu Glu Ile Leu Glu Asn Pro Leu
                 260                 265                 270

 Ile Ala Asp Leu Val Ala Asp Glu Gln Arg Arg Asn Leu Glu Arg
                 275                 280                 285

 Arg Gly Arg Gln Leu Gly Glu Pro Glu Lys Ser Gln Asp Ser Ser
                 290                 295                 300

 Pro Val Leu Ser Glu Leu Lys Leu Lys Glu Ile Gln Leu Gln Glu
                 305                 310                 315

 Arg Glu Arg Ala Leu Lys Ala Arg Glu Glu Arg Leu Glu Gln Lys
                 320                 325                 330

 Glu Gln Glu Leu Cys Val Arg Glu Arg Leu Ala Glu Asp Lys Leu
                 335                 340                 345

 Ala Arg Ala Glu Asn Leu Leu Lys Asn Tyr Ser Leu Leu Lys Glu
                 350                 355                 360

 Arg Lys Phe Leu Ser Leu Ala Ser Asn Pro Glu Leu Leu Asn Leu
                 365                 370                 375

 Pro Ser Ser Val Ile Lys Lys Lys Val His Phe Ser Gly Glu Ser
                 380                 385                 390

 Lys Glu Asn Ile Met Arg Ser Glu Asn Ser Glu Ser Gln Leu Thr
                 395                 400                 405

 Ser Lys Ser Lys Cys Lys Asp Leu Lys Lys Arg Leu His Ala Ala
                 410                 415                 420

 Gln Leu Arg Ala Gln Ala Leu Ser Asp Ile Glu Lys Asn Tyr Gln
                 425                 430                 435

 Leu Lys Ser Arg Gln Ile Leu Gly Met Arg
                 440                 445

<210> 1175
<211> 4407
<212> DNA
<213> Homo sapien

<400> 1175
 tttcgactcg cgctccggct gctgtcactt ggctctctgg ctggagcttg 50

 aggacgcaag gagggtttgt cactggcaga ctcgagactg taggcactgc 100

 catggcccct gtgctcagta aggactcggc ggacatcgag agtatcctgg 150

 ctttaaatcc tcgaacacaa actcatgcaa ctctgtgttc cacttcggcc 200

 aagaaattag acaagaaaca ttggaaaaga aatcctgata agaactgctt 250

 taattgtgag aagctggaga ataattttga tgacatcaag cacacgactc 300

 ttggtgagcg aggagctctc cgagaagcaa tgagatgcct gaaatgtgca 350

 gatgccccgt gtcagaagag ctgtccaact aatcttgata ttaaatcatt 400

 catcacaagt attgcaaaca agaactatta tggagctgct aagatgatat 450

 tttctgacaa cccacttggt ctgacttgtg gaatggtatg tccaacctct 500

 gatctatgtg taggtggatg caatttatat gccactgaag agggacccat 550

 taatattggt ggattgcagc aatttgctac tgaggtattc aaagcaatga 600

 gtatcccaca gatcagaaat ccttcgctgc ctcccccaga aaaaatgtct 650

 gaagcctatt ctgcaaagat tgctcttttt ggtgctgggc ctgcaagtat 700

 aagttgtgct tcctttttgg ctcgattggg gtactctgac atcactatat 750

 ttgaaaaaca agaatatgtt ggtggtttaa gtacttctga aattcctcag 800

 ttccggctgc cgtatgatgt agtgaatttt gagattgagc taatgaagga 850

 ccttggtgta aagataattt gcggtaaaag cctttcagtg aatgaaatga 900

 ctcttagcac tttgaaagaa aaaggctaca aagctgcttt cattggaata 950

 ggtttgccag aacccaataa agatgccatc ttccaaggcc tgacgcagga 1000

 ccaggggttt tatacatcca aagacttttt gccacttgta gccaaaggca 1050

 gtaaagcagg aatgtgcgcc tgtcactctc cattgccatc gatacgggga 1100

 gtcgtgattg tacttggagc tggagacact gccttcgact gtgcaacatc 1150

 tgctctacgt tgtggagctc gccgagtgtt catcgtcttc agaaaaggct 1200

 ttgttaatat aagagctgtc cctgaggaga tggagcttgc taaggaagaa 1250

 aagtgtgaat ttctgccatt cctgtcccca cggaaggtta tagtaaaagg 1300

 tgggagaatt gttgctatgc agtttgttcg gacagagcaa gatgaaactg 1350

 gaaaatggaa tgaagatgaa gatcagatgg tccatctgaa agccgatgtg 1400

 gtcatcagtg cctttggttc agttctgagt gatcctaaag taaaagaagc 1450

 cttgagccct ataaaattta acagatgggg tctcccagaa gtagatccag 1500

 aaactatgca aactagtgaa gcatgggtat ttgcaggtgg tgatgtcgtt 1550

 ggtttggcta acactacagt ggaatcggtg aatgatggaa agcaagcttc 1600

 ttggtacatt cacaaatacg tacagtcaca atatggagct tccgtttctg 1650

 ccaagcctga actacccctc ttttacactc ctattgatct ggtggacatt 1700

 agtgtagaaa tggccggatt gaagtttata aatccttttg gtcttgctag 1750

 cgcaactcca gccaccagca catcaatgat tcgaagagct tttgaagctg 1800

 gatggggttt tgccctcacc aaaactttct ctcttgataa ggacattgtg 1850

 acaaatgttt cccccagaat catccgggga accacctctg gccccatgta 1900

 tggccctgga caaagctcct ttctgaatat tgagctcatc agtgagaaaa 1950

 cggctgcata ttggtgtcaa agtgtcactg aactaaaggc tgacttccca 2000

 gacaacattg tgattgctag cattatgtgc agttacaata aaaatgactg 2050

 gacggaactt gccaagaagt ctgaggattc tggagcagat gccctggagt 2100

 taaatttatc atgtccacat ggcatgggag aaagaggaat gggcctggcc 2150

 tgtgggcagg atccagagct ggtgcggaac atctgccgct gggttaggca 2200

 agctgttcag attccttttt ttgccaagct gaccccaaat gtcactgata 2250

 ttgtgagcat cgcaagagct gcaaaggaag gtggtgccaa tggcgttaca 2300

 gccaccaaca ctgtctcagg tctgatggga ttaaaatctg atggcacacc 2350

 ttggccagca gtggggattg caaagcgaac tacatatgga ggagtgtctg 2400

 ggacagcaat cagacctatt gctttgagag ctgtgacctc cattgctcgt 2450

 gctctgcctg gatttcccat tttggctact ggtggaattg actctgctga 2500

 aagtggtctt cagtttctcc atagtggtgc ttccgtcctc caggtatgca 2550

 gtgccattca gaatcaggat ttcactgtga tcgaagacta ctgcactggc 2600

 ctcaaagccc tgctttatct gaaaagcatt gaagaactac aagactggga 2650

 tggacagagt ccagctactg tgagtcacca gaaagggaaa ccagttccac 2700

 gtatagctga actcatggac aagaaactgc caagttttgg accttatctg 2750

 gaacagcgca agaaaatcat agcagaaaac aagattagac tgaaagaaca 2800

 aaatgtagct ttttcaccac ttaagagaag ctgttttatc cccaaaaggc 2850

 ctattcctac catcaaggat gtaataggaa aagcactgca gtaccttgga 2900

 acatttggtg aattgagcaa cgtagagcaa gttgtggcta tgattgatga 2950

 agaaatgtgt atcaactgtg gtaaatgcta catgacctgt aatgattctg 3000

 gctaccaggc tatacagttt gatccagaaa cccacctgcc caccataacc 3050

 gacacttgta caggctgtac tctgtgtctc agtgtttgcc ctattgtcga 3100

 ctgcatcaaa atggtttcca ggacaacacc ttatgaacca aagagaggcg 3150

 tacccttatc tgtgaatccg gtgtgttaag gtgatttgtg aaacagttgc 3200

 tgtgaacttt catgtcacct acatatgctg atctcttaaa atcatgatcc 3250

 ttgtgttcag ctctttccaa attaaaacaa atatacattt tctaaataaa 3300

 aatatgtaat ttcaaaatac atttgtaagt gtaaaaaatg tctcatgtca 3350

 atgaccattc aattagtggc ataaaataga ataattcttt tctgaggata 3400

 gtagttaaat aactgtgtgg cagttaattg gatgttcact gccagttgtc 3450

 ttatgtgaaa aattaacttt ttgtgtggca attagtgtga cagtttccaa 3500

 attgccctat gctgtgctcc atatttgatt tctaattgta agtgaaatta 3550

 agcattttga aacaaagtac tctttaacat acaagaaaat gtatccaagg 3600

 aaacatttta tcaataaaaa ttacctttaa ttttaatgct gtttctaaga 3650

 aaatgtagtt agctccataa agtacaaatg aagaaagtca aaaattattt 3700

 gctatggcag gataagaaag cctaaaattg agtttgtgga ctttattaag 3750

 taaaatcccc ttcgctgaaa ttgcttattt ttggtgttgg atagaggata 3800

 gggagaatat ttactaacta aataccattc actactcatg cgtgagatgg 3850

 gtgtacaaac tcatcctctt ttaatggcat ttctctttaa actatgttcc 3900

 taaccaaatg agatgatagg atagatcctg gttaccactc ttttactgtg 3950

 cacatatggg ccccggaatt ctttaatagt caccttcatg attatagcaa 4000

 ctaatgtttg aacaaagctc aaagtatgca atgcttcatt attcaagaat 4050

 gaaaaatata atgttgataa tatatattaa gtgtgccaaa tcagtttgac 4100

 tactctctgt tttagtgttt atgtttaaaa gaaatatatt ttttgttatt 4150

 attagataat atttttgtat ttctctattt tcataatcag taaatagtgt 4200

 catataaact catttatctc ctcttcatgg catcttcaat atgaatctat 4250

 aagtagtaaa tcagaaagta acaatctatg gcttatttct atgacaaatt 4300

 caagagctag aaaaataaaa tgtttcatta tgcactttta gaaatgcata 4350

 tttgccacaa aacctgtatt actgaataat atcaaataaa atatcataaa 4400

 gcatttt 4407

<210> 1176
<211> 1025
<212> PRT
<213> Homo sapien

<400> 1176
 Met Ala Pro Val Leu Ser Lys Asp Ser Ala Asp Ile Glu Ser Ile
   1               5                  10                  15

 Leu Ala Leu Asn Pro Arg Thr Gln Thr His Ala Thr Leu Cys Ser
                  20                  25                  30

 Thr Ser Ala Lys Lys Leu Asp Lys Lys His Trp Lys Arg Asn Pro
                  35                  40                  45

 Asp Lys Asn Cys Phe Asn Cys Glu Lys Leu Glu Asn Asn Phe Asp
                  50                  55                  60

 Asp Ile Lys His Thr Thr Leu Gly Glu Arg Gly Ala Leu Arg Glu
                  65                  70                  75

 Ala Met Arg Cys Leu Lys Cys Ala Asp Ala Pro Cys Gln Lys Ser
                  80                  85                  90

 Cys Pro Thr Asn Leu Asp Ile Lys Ser Phe Ile Thr Ser Ile Ala
                  95                 100                 105

 Asn Lys Asn Tyr Tyr Gly Ala Ala Lys Met Ile Phe Ser Asp Asn
                 110                 115                 120

 Pro Leu Gly Leu Thr Cys Gly Met Val Cys Pro Thr Ser Asp Leu
                 125                 130                 135

 Cys Val Gly Gly Cys Asn Leu Tyr Ala Thr Glu Glu Gly Pro Ile
                 140                 145                 150

 Asn Ile Gly Gly Leu Gln Gln Phe Ala Thr Glu Val Phe Lys Ala
                 155                 160                 165

 Met Ser Ile Pro Gln Ile Arg Asn Pro Ser Leu Pro Pro Pro Glu
                 170                 175                 180

 Lys Met Ser Glu Ala Tyr Ser Ala Lys Ile Ala Leu Phe Gly Ala
                 185                 190                 195

 Gly Pro Ala Ser Ile Ser Cys Ala Ser Phe Leu Ala Arg Leu Gly
                 200                 205                 210

 Tyr Ser Asp Ile Thr Ile Phe Glu Lys Gln Glu Tyr Val Gly Gly
                 215                 220                 225

 Leu Ser Thr Ser Glu Ile Pro Gln Phe Arg Leu Pro Tyr Asp Val
                 230                 235                 240

 Val Asn Phe Glu Ile Glu Leu Met Lys Asp Leu Gly Val Lys Ile
                 245                 250                 255

 Ile Cys Gly Lys Ser Leu Ser Val Asn Glu Met Thr Leu Ser Thr
                 260                 265                 270

 Leu Lys Glu Lys Gly Tyr Lys Ala Ala Phe Ile Gly Ile Gly Leu
                 275                 280                 285

 Pro Glu Pro Asn Lys Asp Ala Ile Phe Gln Gly Leu Thr Gln Asp
                 290                 295                 300

 Gln Gly Phe Tyr Thr Ser Lys Asp Phe Leu Pro Leu Val Ala Lys
                 305                 310                 315

 Gly Ser Lys Ala Gly Met Cys Ala Cys His Ser Pro Leu Pro Ser
                 320                 325                 330

 Ile Arg Gly Val Val Ile Val Leu Gly Ala Gly Asp Thr Ala Phe
                 335                 340                 345

 Asp Cys Ala Thr Ser Ala Leu Arg Cys Gly Ala Arg Arg Val Phe
                 350                 355                 360

 Ile Val Phe Arg Lys Gly Phe Val Asn Ile Arg Ala Val Pro Glu
                 365                 370                 375

 Glu Met Glu Leu Ala Lys Glu Glu Lys Cys Glu Phe Leu Pro Phe
                 380                 385                 390

 Leu Ser Pro Arg Lys Val Ile Val Lys Gly Gly Arg Ile Val Ala
                 395                 400                 405

 Met Gln Phe Val Arg Thr Glu Gln Asp Glu Thr Gly Lys Trp Asn
                 410                 415                 420

 Glu Asp Glu Asp Gln Met Val His Leu Lys Ala Asp Val Val Ile
                 425                 430                 435

 Ser Ala Phe Gly Ser Val Leu Ser Asp Pro Lys Val Lys Glu Ala
                 440                 445                 450

 Leu Ser Pro Ile Lys Phe Asn Arg Trp Gly Leu Pro Glu Val Asp
                 455                 460                 465

 Pro Glu Thr Met Gln Thr Ser Glu Ala Trp Val Phe Ala Gly Gly
                 470                 475                 480

 Asp Val Val Gly Leu Ala Asn Thr Thr Val Glu Ser Val Asn Asp
                 485                 490                 495

 Gly Lys Gln Ala Ser Trp Tyr Ile His Lys Tyr Val Gln Ser Gln
                 500                 505                 510

 Tyr Gly Ala Ser Val Ser Ala Lys Pro Glu Leu Pro Leu Phe Tyr
                 515                 520                 525

 Thr Pro Ile Asp Leu Val Asp Ile Ser Val Glu Met Ala Gly Leu
                 530                 535                 540

 Lys Phe Ile Asn Pro Phe Gly Leu Ala Ser Ala Thr Pro Ala Thr
                 545                 550                 555

 Ser Thr Ser Met Ile Arg Arg Ala Phe Glu Ala Gly Trp Gly Phe
                 560                 565                 570

 Ala Leu Thr Lys Thr Phe Ser Leu Asp Lys Asp Ile Val Thr Asn
                 575                 580                 585

 Val Ser Pro Arg Ile Ile Arg Gly Thr Thr Ser Gly Pro Met Tyr
                 590                 595                 600

 Gly Pro Gly Gln Ser Ser Phe Leu Asn Ile Glu Leu Ile Ser Glu
                 605                 610                 615

 Lys Thr Ala Ala Tyr Trp Cys Gln Ser Val Thr Glu Leu Lys Ala
                 620                 625                 630

 Asp Phe Pro Asp Asn Ile Val Ile Ala Ser Ile Met Cys Ser Tyr
                 635                 640                 645

 Asn Lys Asn Asp Trp Thr Glu Leu Ala Lys Lys Ser Glu Asp Ser
                 650                 655                 660

 Gly Ala Asp Ala Leu Glu Leu Asn Leu Ser Cys Pro His Gly Met
                 665                 670                 675

 Gly Glu Arg Gly Met Gly Leu Ala Cys Gly Gln Asp Pro Glu Leu
                 680                 685                 690

 Val Arg Asn Ile Cys Arg Trp Val Arg Gln Ala Val Gln Ile Pro
                 695                 700                 705

 Phe Phe Ala Lys Leu Thr Pro Asn Val Thr Asp Ile Val Ser Ile
                 710                 715                 720

 Ala Arg Ala Ala Lys Glu Gly Gly Ala Asn Gly Val Thr Ala Thr
                 725                 730                 735

 Asn Thr Val Ser Gly Leu Met Gly Leu Lys Ser Asp Gly Thr Pro
                 740                 745                 750

 Trp Pro Ala Val Gly Ile Ala Lys Arg Thr Thr Tyr Gly Gly Val
                 755                 760                 765

 Ser Gly Thr Ala Ile Arg Pro Ile Ala Leu Arg Ala Val Thr Ser
                 770                 775                 780

 Ile Ala Arg Ala Leu Pro Gly Phe Pro Ile Leu Ala Thr Gly Gly
                 785                 790                 795

 Ile Asp Ser Ala Glu Ser Gly Leu Gln Phe Leu His Ser Gly Ala
                 800                 805                 810

 Ser Val Leu Gln Val Cys Ser Ala Ile Gln Asn Gln Asp Phe Thr
                 815                 820                 825

 Val Ile Glu Asp Tyr Cys Thr Gly Leu Lys Ala Leu Leu Tyr Leu
                 830                 835                 840

 Lys Ser Ile Glu Glu Leu Gln Asp Trp Asp Gly Gln Ser Pro Ala
                 845                 850                 855

 Thr Val Ser His Gln Lys Gly Lys Pro Val Pro Arg Ile Ala Glu
                 860                 865                 870

 Leu Met Asp Lys Lys Leu Pro Ser Phe Gly Pro Tyr Leu Glu Gln
                 875                 880                 885

 Arg Lys Lys Ile Ile Ala Glu Asn Lys Ile Arg Leu Lys Glu Gln
                 890                 895                 900

 Asn Val Ala Phe Ser Pro Leu Lys Arg Ser Cys Phe Ile Pro Lys
                 905                 910                 915

 Arg Pro Ile Pro Thr Ile Lys Asp Val Ile Gly Lys Ala Leu Gln
                 920                 925                 930

 Tyr Leu Gly Thr Phe Gly Glu Leu Ser Asn Val Glu Gln Val Val
                 935                 940                 945

 Ala Met Ile Asp Glu Glu Met Cys Ile Asn Cys Gly Lys Cys Tyr
                 950                 955                 960

 Met Thr Cys Asn Asp Ser Gly Tyr Gln Ala Ile Gln Phe Asp Pro
                 965                 970                 975

 Glu Thr His Leu Pro Thr Ile Thr Asp Thr Cys Thr Gly Cys Thr
                 980                 985                 990

 Leu Cys Leu Ser Val Cys Pro Ile Val Asp Cys Ile Lys Met Val
                 995                1000                1005

 Ser Arg Thr Thr Pro Tyr Glu Pro Lys Arg Gly Val Pro Leu Ser
                1010                1015                1020

 Val Asn Pro Val Cys
                1025

<210> 1177
<211> 1160
<212> DNA
<213> Homo sapien

<400> 1177
 cctccgacag cctctccaca ggtaccatga aggtctccgc ggcacgcctc 50

 gctgtcatcc tcattgctac tgccctctgc gctcctgcat ctgcctcccc 100

 atattcctcg gacaccacac cctgctgctt tgcctacatt gcccgcccac 150

 tgccccgtgc ccacatcaag gagtatttct acaccagtgg caagtgctcc 200

 aacccagcag tcgtctttgt cacccgaaag aaccgccaag tgtgtgccaa 250

 cccagagaag aaatgggttc gggagtacat caactctttg gagatgagct 300

 aggatggaga gtccttgaac ctgaacttac acaaatttgc ctgtttctgc 350

 ttgctcttgt cctagcttgg gaggcttccc ctcactatcc taccccaccc 400

 gctccttgaa gggcccagat tctgaccacg acgagcagca gttacaaaaa 450

 ccttccccag gctggacgtg gtggctcagc cttgtaatcc cagcactttg 500

 ggaggccaag gtgggtggat cacttgaggt caggagttcg agacagcctg 550

 gccaacatga tgaaacccca tgtgtactaa aaatacaaaa aattagccgg 600

 gcgtggtagc gggcgcctgt agtcccagct actcgggagg ctgaggcagg 650

 agaatggcgt gaacccggga gcggagcttg cagtgagccg agatcgcgcc 700

 actgcactcc agcctgggcg acagagcgag actccgtctc aaaaaaaaaa 750

 aaaaaaaaaa aaaaaataca aaaattagcc gcgtggtggc ccacgcctgt 800

 aatcccagct actcgggagg ctaaggcagg aaaattgttt gaacccagga 850

 ggtggaggct gcagtgagct gagattgtgc cacttcactc cagcctgggt 900

 gacaaagtga gactccgtca caacaacaac aacaaaaagc ttccccaact 950

 aaagcctaga agagcttctg aggcgctgct ttgtcaaaag gaagtctcta 1000

 ggttctgagc tctggctttg ccttggcttt gcaagggctc tgtgacaagg 1050

 aaggaagtca gcatgcctct agaggcaagg aagggaggaa cactgcactc 1100

 ttaagcttcc gccgtctcaa cccctcacag gagcttactg gcaaacatga 1150

 aaaatcgggg 1160

<210> 1178
<211> 91
<212> PRT
<213> Homo sapien

<400> 1178
 Met Lys Val Ser Ala Ala Arg Leu Ala Val Ile Leu Ile Ala Thr
   1               5                  10                  15

 Ala Leu Cys Ala Pro Ala Ser Ala Ser Pro Tyr Ser Ser Asp Thr
                  20                  25                  30

 Thr Pro Cys Cys Phe Ala Tyr Ile Ala Arg Pro Leu Pro Arg Ala
                  35                  40                  45

 His Ile Lys Glu Tyr Phe Tyr Thr Ser Gly Lys Cys Ser Asn Pro
                  50                  55                  60

 Ala Val Val Phe Val Thr Arg Lys Asn Arg Gln Val Cys Ala Asn
                  65                  70                  75

 Pro Glu Lys Lys Trp Val Arg Glu Tyr Ile Asn Ser Leu Glu Met
                  80                  85                  90

 Ser


<210> 1179
<211> 1097
<212> DNA
<213> Homo sapien

<400> 1179
 tggcccctgg tcctgtcctg ttctccagca tggtgtgtct gaggctccct 50

 ggaggctcct gcatggcagt tctgacagtg acactgatgg tgctgagctc 100

 cccactggct ttggctgggg acaccagacc acgtttcttg gagtactcta 150

 cgtctgagtg tcatttcttc aatgggacgg agcgggtgcg gttcctggac 200

 agatacttct ataaccaaga ggagtacgtg cgcttcgaca gcgacgtggg 250

 ggagttccgg gcggtgacgg agctggggcg gcctgatgag gagtactgga 300

 acagccagaa ggacttcctg gaagacaggc gggccgcggt ggacacctac 350

 tgcagacaca actacggggt tggtgagagc ttcacagtgc agcggcgagt 400

 ccatcctaag gtgactgtgt atccttcaaa gacccagccc ctgcagcacc 450

 acaacctcct ggtctgttct gtgagtggtt tctatccagg cagcattgaa 500

 gtcaggtggt tccggaatgg ccaggaagag aagactgggg tggtgtccac 550

 aggcctgatc cacaatggag actggacctt ccagaccctg gtgatgctgg 600

 aaacagttcc tcggagtgga gaggtttaca cctgccaagt ggagcaccca 650

 agcgtgacaa gccctctcac agtggaatgg agagcacggt ctgaatctgc 700

 acagagcaag atgctgagtg gagtcggggg ctttgtgctg ggcctgctct 750

 tccttggggc cgggctgttc atctacttca ggaatcagaa aggacactct 800

 ggacttcagc caagaggatt cctgagctga agtgcagatg acacattcaa 850

 agaagaactt tctgccccag ctttgcagga tgaaaagctt tccctcctgg 900

 ctgttattct tccacaagag agggctttct caggacctgg ttgctactgg 950

 ttcagcaact gcagaaaatg tcctcccttg tggcttcctc agctcctgtt 1000

 cttggcctga agccccacag ctttgatggc agcgcctcat cttcaacttt 1050

 tgtgctcccc tttgcctaaa ccctatggcc tcctgtgcat ctgtact 1097

<210> 1180
<211> 266
<212> PRT
<213> Homo sapien

<400> 1180
 Met Val Cys Leu Arg Leu Pro Gly Gly Ser Cys Met Ala Val Leu
   1               5                  10                  15

 Thr Val Thr Leu Met Val Leu Ser Ser Pro Leu Ala Leu Ala Gly
                  20                  25                  30

 Asp Thr Arg Pro Arg Phe Leu Glu Tyr Ser Thr Ser Glu Cys His
                  35                  40                  45

 Phe Phe Asn Gly Thr Glu Arg Val Arg Phe Leu Asp Arg Tyr Phe
                  50                  55                  60

 Tyr Asn Gln Glu Glu Tyr Val Arg Phe Asp Ser Asp Val Gly Glu
                  65                  70                  75

 Phe Arg Ala Val Thr Glu Leu Gly Arg Pro Asp Glu Glu Tyr Trp
                  80                  85                  90

 Asn Ser Gln Lys Asp Phe Leu Glu Asp Arg Arg Ala Ala Val Asp
                  95                 100                 105

 Thr Tyr Cys Arg His Asn Tyr Gly Val Gly Glu Ser Phe Thr Val
                 110                 115                 120

 Gln Arg Arg Val His Pro Lys Val Thr Val Tyr Pro Ser Lys Thr
                 125                 130                 135

 Gln Pro Leu Gln His His Asn Leu Leu Val Cys Ser Val Ser Gly
                 140                 145                 150

 Phe Tyr Pro Gly Ser Ile Glu Val Arg Trp Phe Arg Asn Gly Gln
                 155                 160                 165

 Glu Glu Lys Thr Gly Val Val Ser Thr Gly Leu Ile His Asn Gly
                 170                 175                 180

 Asp Trp Thr Phe Gln Thr Leu Val Met Leu Glu Thr Val Pro Arg
                 185                 190                 195

 Ser Gly Glu Val Tyr Thr Cys Gln Val Glu His Pro Ser Val Thr
                 200                 205                 210

 Ser Pro Leu Thr Val Glu Trp Arg Ala Arg Ser Glu Ser Ala Gln
                 215                 220                 225

 Ser Lys Met Leu Ser Gly Val Gly Gly Phe Val Leu Gly Leu Leu
                 230                 235                 240

 Phe Leu Gly Ala Gly Leu Phe Ile Tyr Phe Arg Asn Gln Lys Gly
                 245                 250                 255

 His Ser Gly Leu Gln Pro Arg Gly Phe Leu Ser
                 260                 265

<210> 1181
<211> 983
<212> DNA
<213> Homo sapien

<400> 1181
 ggcacgaggc ctgacatgga gcctgccagc tccgtcagcc ctgactcggc 50

 ccggagctga gctccccacc tgccggtagc ccaggagatg gagcagccca 100

 gcccacgtgc ccggccttcc gcccctgact tcacttgata acaaactaga 150

 aactgaaaca gggtcgggat gccgatgccg gcttggagtt agagatgagt 200

 caccgctgag agcagctgca gtagctgagc agtggcagca gagaggcaga 250

 cgtgagctga gggcgcagag gcaggcagca tctctgaggg tccccaagga 300

 gcatggctgg gagccgtgag gtggtggcca tggactgcga gatggtgggg 350

 ctggggcccc accgggagag tggcctggct cgttgcagcc tcgtgaacgt 400

 ccacggtgct gtgctgtacg acaagttcat ccggcctgag ggagagatca 450

 ccgattacag aacccgggtc agcggggtca cccctcagca catggtgggg 500

 gccacaccat ttgccgtggc caggctagag atcctgcagc tcctgaaagg 550

 caagctggtg gtgggtcatg acctgaagca cgacttccag gcactgaaag 600

 aggacatgag cggctacaca atctacgaca cgtccactga caggctgttg 650

 tggcgtgagg ccaagctgga ccactgcagg cgtgtctccc tgcgggtgct 700

 gagtgagcgc ctcctgcaca agagcatcca gaacagcctg cttggacaca 750

 gctcggtgga agatgcgagg gcaacgatgg agctctatca aatctcccag 800

 agaatccgag cccgccgagg gctgccccgc ctggctgtgt cagactgaag 850

 ccccatccag cccgttccgc agggactaga ggctttcggc tttttgggac 900

 agcaactacc ttgcttttgg aaaatacatt tttaatagta aagtggctct 950

 atattttctc tacgcaaaaa aaaaaaaaaa aaa 983

<210> 1182
<211> 181
<212> PRT
<213> Homo sapien

<400> 1182
 Met Ala Gly Ser Arg Glu Val Val Ala Met Asp Cys Glu Met Val
   1               5                  10                  15

 Gly Leu Gly Pro His Arg Glu Ser Gly Leu Ala Arg Cys Ser Leu
                  20                  25                  30

 Val Asn Val His Gly Ala Val Leu Tyr Asp Lys Phe Ile Arg Pro
                  35                  40                  45

 Glu Gly Glu Ile Thr Asp Tyr Arg Thr Arg Val Ser Gly Val Thr
                  50                  55                  60

 Pro Gln His Met Val Gly Ala Thr Pro Phe Ala Val Ala Arg Leu
                  65                  70                  75

 Glu Ile Leu Gln Leu Leu Lys Gly Lys Leu Val Val Gly His Asp
                  80                  85                  90

 Leu Lys His Asp Phe Gln Ala Leu Lys Glu Asp Met Ser Gly Tyr
                  95                 100                 105

 Thr Ile Tyr Asp Thr Ser Thr Asp Arg Leu Leu Trp Arg Glu Ala
                 110                 115                 120

 Lys Leu Asp His Cys Arg Arg Val Ser Leu Arg Val Leu Ser Glu
                 125                 130                 135

 Arg Leu Leu His Lys Ser Ile Gln Asn Ser Leu Leu Gly His Ser
                 140                 145                 150

 Ser Val Glu Asp Ala Arg Ala Thr Met Glu Leu Tyr Gln Ile Ser
                 155                 160                 165

 Gln Arg Ile Arg Ala Arg Arg Gly Leu Pro Arg Leu Ala Val Ser
                 170                 175                 180

 Asp


<210> 1183
<211> 2618
<212> DNA
<213> Homo sapien

<400> 1183
 atgaagcacc tgaagcggtg gtggtcggcc ggcggcggcc tcctgcacct 50

 caccctcctg ctgagcttgg cggggctccg cgtagaccta gatctttacc 100

 tgctgctgcc gccgcccacc ctgctgcagg acgagctgct gttcctgggc 150

 ggcccggcca gctccgccta cgcgctcagc cccttctcgg cctcgggagg 200

 gtgggggcgc gcgggccact tgcaccccaa gggccgggag ctggaccctg 250

 ccgcgccgcc cgagggccag ctgctccggg aggtgcgcgc gctcggggtc 300

 cccttcgtcc ctcgcaccag cgtggatgca tggctggtgc acagcgtggc 350

 tgccgggagc gcggacgagg cccacgggct gctcggcgcc gccgccgcct 400

 cgtccaccgg aggagccggc gccagcgtgg acggcggcag ccaggctgtg 450

 caggggggcg gcggggaccc ccgagcggct cggagtggcc ccttggacgc 500

 cggggaagag gagaaggcac ccgcggaacc gacggctcag gtgccggacg 550

 ctggcggatg tgcgagcgag gagaatgggg tactaagaga aaagcacgaa 600

 gctgtggatc atagttccca gcatgaggaa aatgaagaaa gggtgtcagc 650

 ccagaaggag aactcacttc agcagaatga tgatgatgaa aacaaaatag 700

 cagagaaacc tgactgggag gcagaaaaga ccactgaatc tagaaatgag 750

 agacatctga atgggacaga tacttctttc tctctggaag acttattcca 800

 gttgctttca tcacagcctg aaaattcact ggagggcatc tcattgggag 850

 atattcctct tccaggcagt atcagtgatg gcatgaattc ttcagcacat 900

 tatcatgtaa acttcagcca ggctataagt caggatgtga atcttcatga 950

 ggccatcttg ctttgtccca acaatacatt tagaagagat ccaacagcaa 1000

 ggacttcaca gtcacaagaa ccatttctgc agttaaattc tcataccacc 1050

 aatcctgagc aaacccttcc tggaactaat ttgacaggat ttctttcacc 1100

 ggttgacaat catatgagga atctaacaag ccaagaccta ctgtatgacc 1150

 ttgacataaa tatatttgat gagataaact taatgtcatt ggccacagaa 1200

 gacaactttg atccaatcga tgtttctcag ctttttgatg aaccagattc 1250

 tgattctggc ctttctttag attcaagtca caataatacc tctgtcatca 1300

 agtctaattc ctctcactct gtgtgtgatg aaggtgctat aggttattgc 1350

 actgaccatg aatctagttc ccatcatgac ttagaaggtg ctgtaggtgg 1400

 ctactaccca gaacccagta agctttgtca cttggatcaa agtgattctg 1450

 atttccatgg agatcttaca tttcaacacg tatttcataa ccacacttac 1500

 cacttacagc caactgcacc agaatctact tctgaacctt ttccgtggcc 1550

 tgggaagtca cagaagataa ggagtagata ccttgaagac acagatagaa 1600

 acttgagccg tgatgaacag cgtgctaaag ctttgcatat ccctttttct 1650

 gtagatgaaa ttgtcggcat gcctgttgat tctttcaata gcatgttaag 1700

 tagatattat ctgacagacc tacaagtctc acttatccgt gacatcagac 1750

 gaagagggaa aaataaagtt gctgcgcaga actgtcgtaa acgcaaattg 1800

 gacataattt tgaatttaga agatgatgta tgtaacttgc aagcaaagaa 1850

 ggaaactctt aagagagagc aagcacaatg taacaaagct attaacataa 1900

 tgaaacagaa actgcatgac ctttatcatg atatttttag tagattaaga 1950

 gatgaccaag gtaggccagt caatcccaac cactatgctc tccagtgtac 2000

 ccatgatgga agtatcttga tagtacccaa agaactggtg gcctcaggcc 2050

 acaaaaagga aacccaaaag ggaaagagaa agtgagaaga aactgaagat 2100

 ggactctatt atgtgaagta gtaatgttca gaaactgatt atttggatca 2150

 gaaaccattg aaactgcttc aagaattgta tctttaagta ctgctacttg 2200

 aataactcag ttaacgctgt tttgaagctt acatggacaa atgtttagga 2250

 cttcaagatc acacttgtgg gcaatctggg ggagccacaa cttttcatga 2300

 agtgcattgt atacaaaatt catagttatg tccaaagaat aggttaacat 2350

 gaaaacccag taagactttc catcttggca gccatccttt ttaagagtaa 2400

 gttggttact tcaaaaagag caaacactgg ggatcaaatt attttaagag 2450

 gtatttcagt tttaaatgca aaatagcctt attttcattt agtttgttag 2500

 cactatagtg agcttttcaa acactatttt aatctttata tttaacttat 2550

 aaattttgct ttctatggaa ataaattttg tatttgtatt aaaaattaac 2600

 ttttcccttt tatacaga 2618

<210> 1184
<211> 694
<212> PRT
<213> Homo sapien

<400> 1184
 Met Lys His Leu Lys Arg Trp Trp Ser Ala Gly Gly Gly Leu Leu
   1               5                  10                  15

 His Leu Thr Leu Leu Leu Ser Leu Ala Gly Leu Arg Val Asp Leu
                  20                  25                  30

 Asp Leu Tyr Leu Leu Leu Pro Pro Pro Thr Leu Leu Gln Asp Glu
                  35                  40                  45

 Leu Leu Phe Leu Gly Gly Pro Ala Ser Ser Ala Tyr Ala Leu Ser
                  50                  55                  60

 Pro Phe Ser Ala Ser Gly Gly Trp Gly Arg Ala Gly His Leu His
                  65                  70                  75

 Pro Lys Gly Arg Glu Leu Asp Pro Ala Ala Pro Pro Glu Gly Gln
                  80                  85                  90

 Leu Leu Arg Glu Val Arg Ala Leu Gly Val Pro Phe Val Pro Arg
                  95                 100                 105

 Thr Ser Val Asp Ala Trp Leu Val His Ser Val Ala Ala Gly Ser
                 110                 115                 120

 Ala Asp Glu Ala His Gly Leu Leu Gly Ala Ala Ala Ala Ser Ser
                 125                 130                 135

 Thr Gly Gly Ala Gly Ala Ser Val Asp Gly Gly Ser Gln Ala Val
                 140                 145                 150

 Gln Gly Gly Gly Gly Asp Pro Arg Ala Ala Arg Ser Gly Pro Leu
                 155                 160                 165

 Asp Ala Gly Glu Glu Glu Lys Ala Pro Ala Glu Pro Thr Ala Gln
                 170                 175                 180

 Val Pro Asp Ala Gly Gly Cys Ala Ser Glu Glu Asn Gly Val Leu
                 185                 190                 195

 Arg Glu Lys His Glu Ala Val Asp His Ser Ser Gln His Glu Glu
                 200                 205                 210

 Asn Glu Glu Arg Val Ser Ala Gln Lys Glu Asn Ser Leu Gln Gln
                 215                 220                 225

 Asn Asp Asp Asp Glu Asn Lys Ile Ala Glu Lys Pro Asp Trp Glu
                 230                 235                 240

 Ala Glu Lys Thr Thr Glu Ser Arg Asn Glu Arg His Leu Asn Gly
                 245                 250                 255

 Thr Asp Thr Ser Phe Ser Leu Glu Asp Leu Phe Gln Leu Leu Ser
                 260                 265                 270

 Ser Gln Pro Glu Asn Ser Leu Glu Gly Ile Ser Leu Gly Asp Ile
                 275                 280                 285

 Pro Leu Pro Gly Ser Ile Ser Asp Gly Met Asn Ser Ser Ala His
                 290                 295                 300

 Tyr His Val Asn Phe Ser Gln Ala Ile Ser Gln Asp Val Asn Leu
                 305                 310                 315

 His Glu Ala Ile Leu Leu Cys Pro Asn Asn Thr Phe Arg Arg Asp
                 320                 325                 330

 Pro Thr Ala Arg Thr Ser Gln Ser Gln Glu Pro Phe Leu Gln Leu
                 335                 340                 345

 Asn Ser His Thr Thr Asn Pro Glu Gln Thr Leu Pro Gly Thr Asn
                 350                 355                 360

 Leu Thr Gly Phe Leu Ser Pro Val Asp Asn His Met Arg Asn Leu
                 365                 370                 375

 Thr Ser Gln Asp Leu Leu Tyr Asp Leu Asp Ile Asn Ile Phe Asp
                 380                 385                 390

 Glu Ile Asn Leu Met Ser Leu Ala Thr Glu Asp Asn Phe Asp Pro
                 395                 400                 405

 Ile Asp Val Ser Gln Leu Phe Asp Glu Pro Asp Ser Asp Ser Gly
                 410                 415                 420

 Leu Ser Leu Asp Ser Ser His Asn Asn Thr Ser Val Ile Lys Ser
                 425                 430                 435

 Asn Ser Ser His Ser Val Cys Asp Glu Gly Ala Ile Gly Tyr Cys
                 440                 445                 450

 Thr Asp His Glu Ser Ser Ser His His Asp Leu Glu Gly Ala Val
                 455                 460                 465

 Gly Gly Tyr Tyr Pro Glu Pro Ser Lys Leu Cys His Leu Asp Gln
                 470                 475                 480

 Ser Asp Ser Asp Phe His Gly Asp Leu Thr Phe Gln His Val Phe
                 485                 490                 495

 His Asn His Thr Tyr His Leu Gln Pro Thr Ala Pro Glu Ser Thr
                 500                 505                 510

 Ser Glu Pro Phe Pro Trp Pro Gly Lys Ser Gln Lys Ile Arg Ser
                 515                 520                 525

 Arg Tyr Leu Glu Asp Thr Asp Arg Asn Leu Ser Arg Asp Glu Gln
                 530                 535                 540

 Arg Ala Lys Ala Leu His Ile Pro Phe Ser Val Asp Glu Ile Val
                 545                 550                 555

 Gly Met Pro Val Asp Ser Phe Asn Ser Met Leu Ser Arg Tyr Tyr
                 560                 565                 570

 Leu Thr Asp Leu Gln Val Ser Leu Ile Arg Asp Ile Arg Arg Arg
                 575                 580                 585

 Gly Lys Asn Lys Val Ala Ala Gln Asn Cys Arg Lys Arg Lys Leu
                 590                 595                 600

 Asp Ile Ile Leu Asn Leu Glu Asp Asp Val Cys Asn Leu Gln Ala
                 605                 610                 615

 Lys Lys Glu Thr Leu Lys Arg Glu Gln Ala Gln Cys Asn Lys Ala
                 620                 625                 630

 Ile Asn Ile Met Lys Gln Lys Leu His Asp Leu Tyr His Asp Ile
                 635                 640                 645

 Phe Ser Arg Leu Arg Asp Asp Gln Gly Arg Pro Val Asn Pro Asn
                 650                 655                 660

 His Tyr Ala Leu Gln Cys Thr His Asp Gly Ser Ile Leu Ile Val
                 665                 670                 675

 Pro Lys Glu Leu Val Ala Ser Gly His Lys Lys Glu Thr Gln Lys
                 680                 685                 690

 Gly Lys Arg Lys


<210> 1185
<211> 3636
<212> DNA
<213> Homo sapien

<400> 1185
 gcagagcacc gcgccttagc cgcgaagttc tagttcttgc tgccggtcct 50

 aacgtcccgc agtcttcgcc agccagccgt cccgcatgcg cgtttgggcg 100

 gcgtggagcc tgctgccatg aagtcagcga gagctaagac accccggaaa 150

 cctaccgtga aaaaagggtc ccaaacgaac cttaaagacc cagttggggt 200

 atactgtagg gtgcgcccac tgggctttcc tgatcaagag tgttgcatag 250

 aagtgatcaa taatacaact gttcagcttc atactcctga gggctacaga 300

 ctcaaccgaa atggagacta taaggagact cagtattcat ttaaacaagt 350

 atttggcact cacaccaccc agaaggaact ctttgatgtt gtggctaatc 400

 ccttggtcaa tgacctcatt catggcaaaa atggtcttct ttttacatat 450

 ggtgtgacgg gaagtggaaa aactcacaca atgactggtt ctccagggga 500

 aggagggctg cttcctcgtt gtttggacat gatctttaac agtatagggt 550

 catttcaagc taaacgatat gttttcaaat ctaatgatag gaatagtatg 600

 gatatacagt gtgaggttga tgccttatta gaacgtcaga aaagagaagc 650

 tatgcccaat ccaaagactt cttctagcaa acgacaagta gatccagagt 700

 ttgcagatat gataactgta caagaattct gcaaagcaga agaggttgat 750

 gaagatagtg tctatggtgt atttgtctct tatattgaaa tatataataa 800

 ttacatatat gatctattgg aagaggtgcc gtttgatccc ataaaaccca 850

 aacctccaca atctaaattg cttcgtgaag ataagaacca taacatgtat 900

 gttgcaggat gtacagaagt tgaagtgaaa tctactgagg aggcttttga 950

 agttttctgg agaggccaga aaaagagacg tattgctaat acccatttga 1000

 atcgtgagtc cagccgttcc catagcgtgt tcaacattaa attagttcag 1050

 gctcccttgg atgcagatgg agacaatgtc ttacaggaaa aagaacaaat 1100

 cactataagt cagttgtcct tggtagatct tgctggaagt gaaagaacta 1150

 accggaccag agcagaaggg aacagattac gtgaagctgg taatattaat 1200

 cagtcactaa tgacgctaag aacatgtatg gatgtcctaa gagagaacca 1250

 aatgtatgga actaacaaga tggttccata tcgagattca aagttaaccc 1300

 atctgttcaa gaactacttt gatggggaag gaaaagtgcg gatgatcgtg 1350

 tgtgtgaacc ccaaggctga agattatgaa gaaaacttgc aagtcatgag 1400

 atttgcggaa gtgactcaag aagttgaagt agcaagacct gtagacaagg 1450

 caatatgtgg tttaacgcct gggaggagat acagaaacca gcctcgaggt 1500

 ccagttggaa atgaaccatt ggttactgac gtggttttgc agagttttcc 1550

 acctttgccg tcatgcgaaa ttttggatat caacgatgag cagacacttc 1600

 caaggctgat tgaagcctta gagaaacgac ataacttacg acaaatgatg 1650

 attgatgagt ttaacaaaca atctaatgct tttaaagctt tgttacaaga 1700

 atttgacaat gctgttttaa gtaaagaaaa ccacatgcaa gggaaactaa 1750

 atgaaaagga gaagatgatc tcaggacaga aattggaaat agaacgactg 1800

 gaaaagaaaa acaaaacttt agaatataag attgagattt tagagaaaac 1850

 aactactatc tatgaggaag ataaacgcaa tttgcaacag gaacttgaaa 1900

 ctcagaacca gaaacttcag cgacagtttt ctgacaaacg cagattagaa 1950

 gccaggttgc aaggcatggt gacagaaacg acaatgaagt gggagaaaga 2000

 atgtgagcgt agagtggcag ccaaacagct ggagatgcag aataaactct 2050

 gggttaaaga tgaaaagctg aaacaactga aggctattgt tactgaacct 2100

 aaaactgaga agccagagag accctctcgg gagcgagatc gagaaaaagt 2150

 tactcaaaga tctgtttctc catcacctgt gcctctttct agtaactata 2200

 ttgctcagat ttccaacggc cagcaactca tgagccagcc acagctacat 2250

 aggcgctcta actcttgcag cagcatttct gtagcttcct gtatttcgga 2300

 atgggagcag aaaattccta cgtacaacac acctctcaaa gtcacatcta 2350

 ttgcaaggcg taggcagcag gagccaggac aaagcaaaac ttgtatcgtg 2400

 tcagacagaa ggcgagggat gtactggact gaaggcaggg aggtggttcc 2450

 tacattcaga aatgagatag aaatagaaga ggatcattgc ggcaggttac 2500

 tctttcaacc tgatcagaac gcaccaccaa ttcgtctccg acacagacga 2550

 tcacgctctg caggagacag atgggtagat cataagcccg cctctaacat 2600

 gcaaactgaa acagtcatgc agccacatgt ccctcatgcc atcacagtat 2650

 ctgttgcaaa tgaaaaggca ctagctaagt gtgagaagta catgctgacc 2700

 caccaggaac tagcctccga tggggagatt gaaactaaac taattaaggg 2750

 tgatatttat aaaacaaggg gtggtggaca atctgttcag tttactgata 2800

 ttgagacttt aaagcaagaa tcaccaaatg gtagtcgaaa acgaagatct 2850

 tccacagtag cacctgccca accagatggt gcagagtctg aatggaccga 2900

 tgtagaaaca aggtgttctg tggctgtgga gatgagagca ggatcccagc 2950

 tgggacctgg atatcagcat cacgcacaac ccaagcgcaa aaagccatga 3000

 actgacagtc ccagtactga aagaacattt tcatttgtgt ggatgatttc 3050

 tcgaaagcca tgccagaagc agtcttccag gtcatcttgt agaactccag 3100

 ctttgttgaa aatcacggac ctcagctaca tcatacactg acccagagca 3150

 aagctttccc tatggttcca aagacaacta gtattcaaca aaccttgtat 3200

 agtatatgtt ttgccatatt taatattaat agcagaggaa gactcctttt 3250

 ttcatcactg tatgaatttt ttataatgtt tttttaaaat atatttcatg 3300

 tatacttata aactaattca cacaagtgtt tgtcttagat gattaaggaa 3350

 gactatatct agatcatgtc tgatttttta ttgtgacttc tccagccctg 3400

 gtctgaattt cttaaggttt tataaacaaa tgctgctatt tattagctgc 3450

 aagaatgcac tttagaacta tttgacaatt cagactttca aaataaagat 3500

 gtaaatgact ggccaataat aaccatttta ggaaggtgtt ttgaattctg 3550

 tatgtatata ttcactttct gacatttaga tatgccaaaa gaattaaaat 3600

 caaaagcact aagaaataaa aaaaaaaaaa aaaaaa 3636

<210> 1186
<211> 960
<212> PRT
<213> Homo sapien

<400> 1186
 Met Lys Ser Ala Arg Ala Lys Thr Pro Arg Lys Pro Thr Val Lys
   1               5                  10                  15

 Lys Gly Ser Gln Thr Asn Leu Lys Asp Pro Val Gly Val Tyr Cys
                  20                  25                  30

 Arg Val Arg Pro Leu Gly Phe Pro Asp Gln Glu Cys Cys Ile Glu
                  35                  40                  45

 Val Ile Asn Asn Thr Thr Val Gln Leu His Thr Pro Glu Gly Tyr
                  50                  55                  60

 Arg Leu Asn Arg Asn Gly Asp Tyr Lys Glu Thr Gln Tyr Ser Phe
                  65                  70                  75

 Lys Gln Val Phe Gly Thr His Thr Thr Gln Lys Glu Leu Phe Asp
                  80                  85                  90

 Val Val Ala Asn Pro Leu Val Asn Asp Leu Ile His Gly Lys Asn
                  95                 100                 105

 Gly Leu Leu Phe Thr Tyr Gly Val Thr Gly Ser Gly Lys Thr His
                 110                 115                 120

 Thr Met Thr Gly Ser Pro Gly Glu Gly Gly Leu Leu Pro Arg Cys
                 125                 130                 135

 Leu Asp Met Ile Phe Asn Ser Ile Gly Ser Phe Gln Ala Lys Arg
                 140                 145                 150

 Tyr Val Phe Lys Ser Asn Asp Arg Asn Ser Met Asp Ile Gln Cys
                 155                 160                 165

 Glu Val Asp Ala Leu Leu Glu Arg Gln Lys Arg Glu Ala Met Pro
                 170                 175                 180

 Asn Pro Lys Thr Ser Ser Ser Lys Arg Gln Val Asp Pro Glu Phe
                 185                 190                 195

 Ala Asp Met Ile Thr Val Gln Glu Phe Cys Lys Ala Glu Glu Val
                 200                 205                 210

 Asp Glu Asp Ser Val Tyr Gly Val Phe Val Ser Tyr Ile Glu Ile
                 215                 220                 225

 Tyr Asn Asn Tyr Ile Tyr Asp Leu Leu Glu Glu Val Pro Phe Asp
                 230                 235                 240

 Pro Ile Lys Pro Lys Pro Pro Gln Ser Lys Leu Leu Arg Glu Asp
                 245                 250                 255

 Lys Asn His Asn Met Tyr Val Ala Gly Cys Thr Glu Val Glu Val
                 260                 265                 270

 Lys Ser Thr Glu Glu Ala Phe Glu Val Phe Trp Arg Gly Gln Lys
                 275                 280                 285

 Lys Arg Arg Ile Ala Asn Thr His Leu Asn Arg Glu Ser Ser Arg
                 290                 295                 300

 Ser His Ser Val Phe Asn Ile Lys Leu Val Gln Ala Pro Leu Asp
                 305                 310                 315

 Ala Asp Gly Asp Asn Val Leu Gln Glu Lys Glu Gln Ile Thr Ile
                 320                 325                 330

 Ser Gln Leu Ser Leu Val Asp Leu Ala Gly Ser Glu Arg Thr Asn
                 335                 340                 345

 Arg Thr Arg Ala Glu Gly Asn Arg Leu Arg Glu Ala Gly Asn Ile
                 350                 355                 360

 Asn Gln Ser Leu Met Thr Leu Arg Thr Cys Met Asp Val Leu Arg
                 365                 370                 375

 Glu Asn Gln Met Tyr Gly Thr Asn Lys Met Val Pro Tyr Arg Asp
                 380                 385                 390

 Ser Lys Leu Thr His Leu Phe Lys Asn Tyr Phe Asp Gly Glu Gly
                 395                 400                 405

 Lys Val Arg Met Ile Val Cys Val Asn Pro Lys Ala Glu Asp Tyr
                 410                 415                 420

 Glu Glu Asn Leu Gln Val Met Arg Phe Ala Glu Val Thr Gln Glu
                 425                 430                 435

 Val Glu Val Ala Arg Pro Val Asp Lys Ala Ile Cys Gly Leu Thr
                 440                 445                 450

 Pro Gly Arg Arg Tyr Arg Asn Gln Pro Arg Gly Pro Val Gly Asn
                 455                 460                 465

 Glu Pro Leu Val Thr Asp Val Val Leu Gln Ser Phe Pro Pro Leu
                 470                 475                 480

 Pro Ser Cys Glu Ile Leu Asp Ile Asn Asp Glu Gln Thr Leu Pro
                 485                 490                 495

 Arg Leu Ile Glu Ala Leu Glu Lys Arg His Asn Leu Arg Gln Met
                 500                 505                 510

 Met Ile Asp Glu Phe Asn Lys Gln Ser Asn Ala Phe Lys Ala Leu
                 515                 520                 525

 Leu Gln Glu Phe Asp Asn Ala Val Leu Ser Lys Glu Asn His Met
                 530                 535                 540

 Gln Gly Lys Leu Asn Glu Lys Glu Lys Met Ile Ser Gly Gln Lys
                 545                 550                 555

 Leu Glu Ile Glu Arg Leu Glu Lys Lys Asn Lys Thr Leu Glu Tyr
                 560                 565                 570

 Lys Ile Glu Ile Leu Glu Lys Thr Thr Thr Ile Tyr Glu Glu Asp
                 575                 580                 585

 Lys Arg Asn Leu Gln Gln Glu Leu Glu Thr Gln Asn Gln Lys Leu
                 590                 595                 600

 Gln Arg Gln Phe Ser Asp Lys Arg Arg Leu Glu Ala Arg Leu Gln
                 605                 610                 615

 Gly Met Val Thr Glu Thr Thr Met Lys Trp Glu Lys Glu Cys Glu
                 620                 625                 630

 Arg Arg Val Ala Ala Lys Gln Leu Glu Met Gln Asn Lys Leu Trp
                 635                 640                 645

 Val Lys Asp Glu Lys Leu Lys Gln Leu Lys Ala Ile Val Thr Glu
                 650                 655                 660

 Pro Lys Thr Glu Lys Pro Glu Arg Pro Ser Arg Glu Arg Asp Arg
                 665                 670                 675

 Glu Lys Val Thr Gln Arg Ser Val Ser Pro Ser Pro Val Pro Leu
                 680                 685                 690

 Ser Ser Asn Tyr Ile Ala Gln Ile Ser Asn Gly Gln Gln Leu Met
                 695                 700                 705

 Ser Gln Pro Gln Leu His Arg Arg Ser Asn Ser Cys Ser Ser Ile
                 710                 715                 720

 Ser Val Ala Ser Cys Ile Ser Glu Trp Glu Gln Lys Ile Pro Thr
                 725                 730                 735

 Tyr Asn Thr Pro Leu Lys Val Thr Ser Ile Ala Arg Arg Arg Gln
                 740                 745                 750

 Gln Glu Pro Gly Gln Ser Lys Thr Cys Ile Val Ser Asp Arg Arg
                 755                 760                 765

 Arg Gly Met Tyr Trp Thr Glu Gly Arg Glu Val Val Pro Thr Phe
                 770                 775                 780

 Arg Asn Glu Ile Glu Ile Glu Glu Asp His Cys Gly Arg Leu Leu
                 785                 790                 795

 Phe Gln Pro Asp Gln Asn Ala Pro Pro Ile Arg Leu Arg His Arg
                 800                 805                 810

 Arg Ser Arg Ser Ala Gly Asp Arg Trp Val Asp His Lys Pro Ala
                 815                 820                 825

 Ser Asn Met Gln Thr Glu Thr Val Met Gln Pro His Val Pro His
                 830                 835                 840

 Ala Ile Thr Val Ser Val Ala Asn Glu Lys Ala Leu Ala Lys Cys
                 845                 850                 855

 Glu Lys Tyr Met Leu Thr His Gln Glu Leu Ala Ser Asp Gly Glu
                 860                 865                 870

 Ile Glu Thr Lys Leu Ile Lys Gly Asp Ile Tyr Lys Thr Arg Gly
                 875                 880                 885

 Gly Gly Gln Ser Val Gln Phe Thr Asp Ile Glu Thr Leu Lys Gln
                 890                 895                 900

 Glu Ser Pro Asn Gly Ser Arg Lys Arg Arg Ser Ser Thr Val Ala
                 905                 910                 915

 Pro Ala Gln Pro Asp Gly Ala Glu Ser Glu Trp Thr Asp Val Glu
                 920                 925                 930

 Thr Arg Cys Ser Val Ala Val Glu Met Arg Ala Gly Ser Gln Leu
                 935                 940                 945

 Gly Pro Gly Tyr Gln His His Ala Gln Pro Lys Arg Lys Lys Pro
                 950                 955                 960

<210> 1187
<211> 6914
<212> DNA
<213> Homo sapien

<400> 1187
 tcattgcagc tgggacagcc cggagtgtgg ttagcagctc ggcaagcgct 50

 gcccaggtcc tggggtggtg gcagccagcg ggagcaggaa aggaagcatg 100

 ttcccaggct gcccacgcct ctgggtcctg gtggtcttgg gcaccagctg 150

 ggtaggctgg gggagccaag ggacagaagc ggcacagcta aggcagttct 200

 acgtggctgc tcagggcatc agttggagct accgacctga gcccacaaac 250

 tcaagtttga atctttctgt aacttccttt aagaaaattg tctacagaga 300

 gtatgaacca tattttaaga aagaaaaacc acaatctacc atttcaggac 350

 ttcttgggcc tactttatat gctgaagtcg gagacatcat aaaagttcac 400

 tttaaaaata aggcagataa gcccttgagc atccatcctc aaggaattag 450

 gtacagtaaa ttatcagaag gtgcttctta ccttgaccac acattccctg 500

 cagagaagat ggacgacgct gtggctccag gccgagaata cacctatgaa 550

 tggagtatca gtgaggacag tggacccacc catgatgacc ctccatgcct 600

 cacacacatc tattactccc atgaaaatct gatcgaggat ttcaactctg 650

 ggctgattgg gcccctgctt atctgtaaaa aagggaccct aactgagggt 700

 gggacacaga agacgtttga caagcaaatc gtgctactat ttgctgtgtt 750

 tgatgaaagc aagagctgga gccagtcatc atccctaatg tacacagtca 800

 atggatatgt gaatgggaca atgccagata taacagtttg tgcccatgac 850

 cacatcagct ggcatctgct gggaatgagc tcggggccag aattattctc 900

 cattcatttc aacggccagg tcctggagca gaaccatcat aaggtctcag 950

 ccatcaccct tgtcagtgct acatccacta ccgcaaatat gactgtgggc 1000

 ccagagggaa agtggatcat atcttctctc accccaaaac atttgcaagc 1050

 tgggatgcag gcttacattg acattaaaaa ctgcccaaag aaaaccagga 1100

 atcttaagaa aataactcgt gagcagaggc ggcacatgaa gaggtgggaa 1150

 tacttcattg ctgcagagga agtcatttgg gactatgcac ctgtaatacc 1200

 agcgaatatg gacaaaaaat acaggtctca gcatttggat aatttctcaa 1250

 accaaattgg aaaacattat aagaaagtta tgtacacaca gtacgaagat 1300

 gagtccttca ccaaacatac agtgaatccc aatatgaaag aagatgggat 1350

 tttgggtcct attatcagag cccaggtcag agacacactc aaaatcgtgt 1400

 tcaaaaatat ggccagccgc ccctatagca tttaccctca tggagtgacc 1450

 ttctcgcctt atgaagatga agtcaactct tctttcacct caggcaggaa 1500

 caacaccatg atcagagcag ttcaaccagg ggaaacctat acttataagt 1550

 ggaacatctt agagtttgat gaacccacag aaaatgatgc ccagtgctta 1600

 acaagaccat actacagtga cgtggacatc atgagagaca tcgcctctgg 1650

 gctaatagga ctacttctaa tctgtaagag cagatccctg gacaggcgag 1700

 gaatacagag ggcagcagac atcgaacagc aggctgtgtt tgctgtgttt 1750

 gatgagaaca aaagctggta ccttgaggac aacatcaaca agttttgtga 1800

 aaatcctgat gaggtgaaac gtgatgaccc caagttttat gaatcaaaca 1850

 tcatgagcac tatcaatggc tatgtgcctg agagcataac tactcttgga 1900

 ttctgctttg atgacactgt ccagtggcac ttctgtagtg tggggaccca 1950

 gaatgaaatt ttgaccatcc acttcactgg gcactcattc atctatggaa 2000

 agaggcatga ggacaccttg accctcttcc ccatgcgtgg agaatctgtg 2050

 acggtcacaa tggataatgt tggaacttgg atgttaactt ccatgaattc 2100

 tagtccaaga agcaaaaagc tgaggctgaa attcagggat gttaaatgta 2150

 tcccagatga tgatgaagac tcatatgaga tttttgaacc tccagaatct 2200

 acagtcatgg ctacacggaa aatgcatgat cgtttagaac ctgaagatga 2250

 agagagtgat gctgactatg attaccagaa cagactggct gcagcattag 2300

 gaattaggtc attccgaaac tcatcattga accaggaaga agaagagttc 2350

 aatcttactg ccctagctct ggagaatggc actgaattcg tttcttcgaa 2400

 cacagatata attgttggtt caaattattc ttccccaagt aatattagta 2450

 agttcactgt caataacctt gcagaacctc agaaagcccc ttctcaccaa 2500

 caagccacca cagctggttc cccactgaga cacctcattg gcaagaactc 2550

 agttctcaat tcttccacag cagagcattc cagcccatat tctgaagacc 2600

 ctatagagga tcctctacag ccagatgtca cagggatacg tctactttca 2650

 cttggtgctg gagaattcag aagtcaagaa catgctaagc gtaagggacc 2700

 caaggtagaa agagatcaag cagcaaagca caggttctcc tggatgaaat 2750

 tactagcaca taaagttggg agacacctaa gccaagacac tggttctcct 2800

 tccggaatga ggccctggga ggaccttcct agccaagaca ctggttctcc 2850

 ttccagaatg aggccctggg aggaccctcc tagtgatctg ttactcttaa 2900

 aacaaagtaa ctcatctaag attttggttg ggagatggca tttggcttct 2950

 gagaaaggta gctatgaaat aatccaagat actgatgaag acacagctgt 3000

 taacaattgg ctgatcagcc cccagaatgc ctcacgtgct tggggagaaa 3050

 gcacccctct tgccaacaag cctggaaagc agagtggcca cccaaagttt 3100

 cctagagtta gacataaatc tctacaagta agacaggatg gaggaaagag 3150

 tagactgaag aaaagccagt ttctcattaa gacacgaaaa aagaaaaaag 3200

 agaagcacac acaccatgct cctttatctc cgaggacctt tcaccctcta 3250

 agaagtgaag cctacaacac attttcagaa agaagactta agcattcgtt 3300

 ggtgcttcat aaatccaatg aaacatctct tcccacagac ctcaatcaga 3350

 cattgccctc tatggatttt ggctggatag cctcacttcc tgaccataat 3400

 cagaattcct caaatgacac tggtcaggca agctgtcctc caggtcttta 3450

 tcagacagtg cccccagagg aacactatca aacattcccc attcaagacc 3500

 ctgatcaaat gcactctact tcagacccca gtcacagatc ctcttctcca 3550

 gagctcagtg aaatgcttga gtatgaccga agtcacaagt ccttccccac 3600

 agatataagt caaatgtccc cttcctcaga acatgaagtc tggcagacag 3650

 tcatctctcc agacctcagc caggtgaccc tctctccaga actcagccag 3700

 acaaacctct ctccagacct cagccacacg actctctctc cagaactcat 3750

 tcagagaaac ctttccccag ccctcggtca gatgcccatt tctccagacc 3800

 tcagccatac aaccctttct ccagacctca gccatacaac cctttcttta 3850

 gacctcagcc agacaaacct ctctccagaa ctcagtcaga caaacctttc 3900

 tccagccctc ggtcagatgc ccctttctcc agacctcagc catacaacca 3950

 tttctctaga cttcagccag acaaacctct ctccagaact cagccatatg 4000

 actctctctc cagaactcag tcagacaaac ctttccccag ccctcggtca 4050

 gatgcccatt tctccagacc tcagccatac aaccctttct ctagacttca 4100

 gccagacaaa cctctctcca gaactcagtc aaacaaacct ttccccagcc 4150

 ctcggtcaga tgcccctttc tccagacccc agccatacaa ccctttctct 4200

 agacctcagc cagacaaacc tctctccaga actcagtcag acaaaccttt 4250

 ccccagacct cagtgagatg cccctctttg cagatctcag tcaaattccc 4300

 cttaccccag acctcgacca gatgacactt tctccagacc ttggtgagac 4350

 agatctttcc ccaaactttg gtcagatgtc cctttcccca gacctcagcc 4400

 aggtgactct ctctccagac atcagtgaca ccacccttct cccggatctc 4450

 agccagatat cacctcctcc agaccttgat cagatattct acccttctga 4500

 atctagtcag tcattgcttc ttcaagaatt taatgagtct tttccttatc 4550

 cagaccttgg tcagatgcca tctccttcat ctcctactct caatgatact 4600

 tttctatcaa aggaatttaa tccactggtt atagtgggcc tcagtaaaga 4650

 tggtacagat tacattgaga tcattccaaa ggaagaggtc cagagcagtg 4700

 aagatgacta tgctgaaatt gattatgtgc cctatgatga cccctacaaa 4750

 actgatgtta ggacaaacat caactcctcc agagatcctg acaacattgc 4800

 agcatggtac ctccgcagca acaatggaaa cagaagaaat tattacattg 4850

 ctgctgaaga aatatcctgg gattattcag aatttgtaca aagggaaaca 4900

 gatattgaag actctgatga tattccagaa gataccacat ataagaaagt 4950

 agtttttcga aagtacctcg acagcacttt taccaaacgt gatcctcgag 5000

 gggagtatga agagcatctc ggaattcttg gtcctattat cagagctgaa 5050

 gtggatgatg ttatccaagt tcgttttaaa aatttagcat ccagaccgta 5100

 ttctctacat gcccatggac tttcctatga aaaatcatca gagggaaaga 5150

 cttatgaaga tgactctcct gaatggttta aggaagataa tgctgttcag 5200

 ccaaatagca gttataccta cgtatggcat gccactgagc gatcagggcc 5250

 agaaagtcct ggctctgcct gtcgggcttg ggcctactac tcagctgtga 5300

 acccagaaaa agatattcac tcaggcttga taggtcccct cctaatctgc 5350

 caaaaaggaa tactacataa ggacagcaac atgcctgtgg acatgagaga 5400

 atttgtctta ctatttatga cctttgatga aaagaagagc tggtactatg 5450

 aaaagaagtc ccgaagttct tggagactca catcctcaga aatgaaaaaa 5500

 tcccatgagt ttcacgccat taatgggatg atctacagct tgcctggcct 5550

 gaaaatgtat gagcaagagt gggtgaggtt acacctgctg aacataggcg 5600

 gctcccaaga cattcacgtg gttcactttc acggccagac cttgctggaa 5650

 aatggcaata aacagcacca gttaggggtc tggccccttc tgcctggttc 5700

 atttaaaact cttgaaatga aggcatcaaa acctggctgg tggctcctaa 5750

 acacagaggt tggagaaaac cagagagcag ggatgcaaac gccatttctt 5800

 atcatggaca gagactgtag gatgccaatg ggactaagca ctggtatcat 5850

 atctgattca cagatcaagg cttcagagtt tctgggttac tgggagccca 5900

 gattagcaag attaaacaat ggtggatctt ataatgcttg gagtgtagaa 5950

 aaacttgcag cagaatttgc ctctaaacct tggatccagg tggacatgca 6000

 aaaggaagtc ataatcacag ggatccagac ccaaggtgcc aaacactacc 6050

 tgaagtcctg ctataccaca gagttctatg tagcttacag ttccaaccag 6100

 atcaactggc agatcttcaa agggaacagc acaaggaatg tgatgtattt 6150

 taatggcaat tcagatgcct ctacaataaa agagaatcag tttgacccac 6200

 ctattgtggc tagatatatt aggatctctc caactcgagc ctataacaga 6250

 cctacccttc gattggaact gcaaggttgt gaggtaaatg gatgttccac 6300

 acccctgggt atggaaaatg gaaagataga aaacaagcaa atcacagctt 6350

 cttcgtttaa gaaatcttgg tggggagatt actgggaacc cttccgtgcc 6400

 cgtctgaatg cccagggacg tgtgaatgcc tggcaagcca aggcaaacaa 6450

 caataagcag tggctagaaa ttgatctact caagatcaag aagataacgg 6500

 caattataac acagggctgc aagtctctgt cctctgaaat gtatgtaaag 6550

 agctatacca tccactacag tgagcaggga gtggaatgga aaccatacag 6600

 gctgaaatcc tccatggtgg acaagatttt tgaaggaaat actaatacca 6650

 aaggacatgt gaagaacttt ttcaaccccc caatcatttc caggtttatc 6700

 cgtgtcattc ctaaaacatg gaatcaaagt attgcacttc gcctggaact 6750

 ctttggctgt gatatttact agaattgaac attcaaaaac ccctggaaga 6800

 gactctttaa gacctcaaac catttagaat gggcaatgta ttttacgctg 6850

 tgttaaatgt taacagtttt ccactatttc tctttctttt ctattagtga 6900

 ataaaatttt atac 6914

<210> 1188
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1188
 Met Phe Pro Gly Cys Pro Arg Leu Trp Val Leu Val Val Leu Gly
   1               5                  10                  15

 Thr Ser Trp Val Gly Trp Gly Ser Gln Gly Thr Glu Ala Ala Gln
                  20                  25                  30

 Leu Arg Gln Phe Tyr Val Ala Ala Gln Gly Ile Ser Trp Ser Tyr
                  35                  40                  45

 Arg Pro Glu Pro Thr Asn Ser Ser Leu Asn Leu Ser Val Thr Ser
                  50                  55                  60

 Phe Lys Lys Ile Val Tyr Arg Glu Tyr Glu Pro Tyr Phe Lys Lys
                  65                  70                  75

 Glu Lys Pro Gln Ser Thr Ile Ser Gly Leu Leu Gly Pro Thr Leu
                  80                  85                  90

 Tyr Ala Glu Val Gly Asp Ile Ile Lys Val His Phe Lys Asn Lys
                  95                 100                 105

 Ala Asp Lys Pro Leu Ser Ile His Pro Gln Gly Ile Arg Tyr Ser
                 110                 115                 120

 Lys Leu Ser Glu Gly Ala Ser Tyr Leu Asp His Thr Phe Pro Ala
                 125                 130                 135

 Glu Lys Met Asp Asp Ala Val Ala Pro Gly Arg Glu Tyr Thr Tyr
                 140                 145                 150

 Glu Trp Ser Ile Ser Glu Asp Ser Gly Pro Thr His Asp Asp Pro
                 155                 160                 165

 Pro Cys Leu Thr His Ile Tyr Tyr Ser His Glu Asn Leu Ile Glu
                 170                 175                 180

 Asp Phe Asn Ser Gly Leu Ile Gly Pro Leu Leu Ile Cys Lys Lys
                 185                 190                 195

 Gly Thr Leu Thr Glu Gly Gly Thr Gln Lys Thr Phe Asp Lys Gln
                 200                 205                 210

 Ile Val Leu Leu Phe Ala Val Phe Asp Glu Ser Lys Ser Trp Ser
                 215                 220                 225

 Gln Ser Ser Ser Leu Met Tyr Thr Val Asn Gly Tyr Val Asn Gly
                 230                 235                 240

 Thr Met Pro Asp Ile Thr Val Cys Ala His Asp His Ile Ser Trp
                 245                 250                 255

 His Leu Leu Gly Met Ser Ser Gly Pro Glu Leu Phe Ser Ile His
                 260                 265                 270

 Phe Asn Gly Gln Val Leu Glu Gln Asn His His Lys Val Ser Ala
                 275                 280                 285

 Ile Thr Leu Val Ser Ala Thr Ser Thr Thr Ala Asn Met Thr Val
                 290                 295                 300

 Gly Pro Glu Gly Lys Trp Ile Ile Ser Ser Leu Thr Pro Lys His
                 305                 310                 315

 Leu Gln Ala Gly Met Gln Ala Tyr Ile Asp Ile Lys Asn Cys Pro
                 320                 325                 330

 Lys Lys Thr Arg Asn Leu Lys Lys Ile Thr Arg Glu Gln Arg Arg
                 335                 340                 345

 His Met Lys Arg Trp Glu Tyr Phe Ile Ala Ala Glu Glu Val Ile
                 350                 355                 360

 Trp Asp Tyr Ala Pro Val Ile Pro Ala Asn Met Asp Lys Lys Tyr
                 365                 370                 375

 Arg Ser Gln His Leu Asp Asn Phe Ser Asn Gln Ile Gly Lys His
                 380                 385                 390

 Tyr Lys Lys Val Met Tyr Thr Gln Tyr Glu Asp Glu Ser Phe Thr
                 395                 400                 405

 Lys His Thr Val Asn Pro Asn Met Lys Glu Asp Gly Ile Leu Gly
                 410                 415                 420

 Pro Ile Ile Arg Ala Gln Val Arg Asp Thr Leu Lys Ile Val Phe
                 425                 430                 435

 Lys Asn Met Ala Ser Arg Pro Tyr Ser Ile Tyr Pro His Gly Val
                 440                 445                 450

 Thr Phe Ser Pro Tyr Glu Asp Glu Val Asn Ser Ser Phe Thr Ser
                 455                 460                 465

 Gly Arg Asn Asn Thr Met Ile Arg Ala Val Gln Pro Gly Glu Thr
                 470                 475                 480

 Tyr Thr Tyr Lys Trp Asn Ile Leu Glu Phe Asp Glu Pro Thr Glu
                 485                 490                 495

 Asn Asp Ala Gln Cys Leu Thr Arg Pro Tyr Tyr Ser Asp Val Asp
                 500                 505                 510

 Ile Met Arg Asp Ile Ala Ser Gly Leu Ile Gly Leu Leu Leu Ile
                 515                 520                 525

 Cys Lys Ser Arg Ser Leu Asp Arg Arg Gly Ile Gln Arg Ala Ala
                 530                 535                 540

 Asp Ile Glu Gln Gln Ala Val Phe Ala Val Phe Asp Glu Asn Lys
                 545                 550                 555

 Ser Trp Tyr Leu Glu Asp Asn Ile Asn Lys Phe Cys Glu Asn Pro
                 560                 565                 570

 Asp Glu Val Lys Arg Asp Asp Pro Lys Phe Tyr Glu Ser Asn Ile
                 575                 580                 585

 Met Ser Thr Ile Asn Gly Tyr Val Pro Glu Ser Ile Thr Thr Leu
                 590                 595                 600

 Gly Phe Cys Phe Asp Asp Thr Val Gln Trp His Phe Cys Ser Val
                 605                 610                 615

 Gly Thr Gln Asn Glu Ile Leu Thr Ile His Phe Thr Gly His Ser
                 620                 625                 630

 Phe Ile Tyr Gly Lys Arg His Glu Asp Thr Leu Thr Leu Phe Pro
                 635                 640                 645

 Met Arg Gly Glu Ser Val Thr Val Thr Met Asp Asn Val Gly Thr
                 650                 655                 660

 Trp Met Leu Thr Ser Met Asn Ser Ser Pro Arg Ser Lys Lys Leu
                 665                 670                 675

 Arg Leu Lys Phe Arg Asp Val Lys Cys Ile Pro Asp Asp Asp Glu
                 680                 685                 690

 Asp Ser Tyr Glu Ile Phe Glu Pro Pro Glu Ser Thr Val Met Ala
                 695                 700                 705

 Thr Arg Lys Met His Asp Arg Leu Glu Pro Glu Asp Glu Glu Ser
                 710                 715                 720

 Asp Ala Asp Tyr Asp Tyr Gln Asn Arg Leu Ala Ala Ala Leu Gly
                 725                 730                 735

 Ile Arg Ser Phe Arg Asn Ser Ser Leu Asn Gln Glu Glu Glu Glu
                 740                 745                 750

 Phe Asn Leu Thr Ala Leu Ala Leu Glu Asn Gly Thr Glu Phe Val
                 755                 760                 765

 Ser Ser Asn Thr Asp Ile Ile Val Gly Ser Asn Tyr Ser Ser Pro
                 770                 775                 780

 Ser Asn Ile Ser Lys Phe Thr Val Asn Asn Leu Ala Glu Pro Gln
                 785                 790                 795

 Lys Ala Pro Ser His Gln Gln Ala Thr Thr Ala Gly Ser Pro Leu
                 800                 805                 810

 Arg His Leu Ile Gly Lys Asn Ser Val Leu Asn Ser Ser Thr Ala
                 815                 820                 825

 Glu His Ser Ser Pro Tyr Ser Glu Asp Pro Ile Glu Asp Pro Leu
                 830                 835                 840

 Gln Pro Asp Val Thr Gly Ile Arg Leu Leu Ser Leu Gly Ala Gly
                 845                 850                 855

 Glu Phe Arg Ser Gln Glu His Ala Lys Arg Lys Gly Pro Lys Val
                 860                 865                 870

 Glu Arg Asp Gln Ala Ala Lys His Arg Phe Ser Trp Met Lys Leu
                 875                 880                 885

 Leu Ala His Lys Val Gly Arg His Leu Ser Gln Asp Thr Gly Ser
                 890                 895                 900

 Pro Ser Gly Met Arg Pro Trp Glu Asp Leu Pro Ser Gln Asp Thr
                 905                 910                 915

 Gly Ser Pro Ser Arg Met Arg Pro Trp Glu Asp Pro Pro Ser Asp
                 920                 925                 930

 Leu Leu Leu Leu Lys Gln Ser Asn Ser Ser Lys Ile Leu Val Gly
                 935                 940                 945

 Arg Trp His Leu Ala Ser Glu Lys Gly Ser Tyr Glu Ile Ile Gln
                 950                 955                 960

 Asp Thr Asp Glu Asp Thr Ala Val Asn Asn Trp Leu Ile Ser Pro
                 965                 970                 975

 Gln Asn Ala Ser Arg Ala Trp Gly Glu Ser Thr Pro Leu Ala Asn
                 980                 985                 990

 Lys Pro Gly Lys Gln Ser Gly His Pro Lys Phe Pro Arg Val Arg
                 995                1000                1005

 His Lys Ser Leu Gln Val Arg Gln Asp Gly Gly Lys Ser Arg Leu
                1010                1015                1020

 Lys Lys Ser Gln Phe Leu Ile Lys Thr Arg Lys Lys Lys Lys Glu
                1025                1030                1035

 Lys His Thr His His Ala Pro Leu Ser Pro Arg Thr Phe His Pro
                1040                1045                1050

 Leu Arg Ser Glu Ala Tyr Asn Thr Phe Ser Glu Arg Arg Leu Lys
                1055                1060                1065

 His Ser Leu Val Leu His Lys Ser Asn Glu Thr Ser Leu Pro Thr
                1070                1075                1080

 Asp Leu Asn Gln Thr Leu Pro Ser Met Asp Phe Gly Trp Ile Ala
                1085                1090                1095

 Ser Leu Pro Asp His Asn Gln Asn Ser Ser Asn Asp Thr Gly Gln
                1100                1105                1110

 Ala Ser Cys Pro Pro Gly Leu Tyr Gln Thr Val Pro Pro Glu Glu
                1115                1120                1125

 His Tyr Gln Thr Phe Pro Ile Gln Asp Pro Asp Gln Met His Ser
                1130                1135                1140

 Thr Ser Asp Pro Ser His Arg Ser Ser Ser Pro Glu Leu Ser Glu
                1145                1150                1155

 Met Leu Glu Tyr Asp Arg Ser His Lys Ser Phe Pro Thr Asp Ile
                1160                1165                1170

 Ser Gln Met Ser Pro Ser Ser Glu His Glu Val Trp Gln Thr Val
                1175                1180                1185

 Ile Ser Pro Asp Leu Ser Gln Val Thr Leu Ser Pro Glu Leu Ser
                1190                1195                1200

 Gln Thr Asn Leu Ser Pro Asp Leu Ser His Thr Thr Leu Ser Pro
                1205                1210                1215

 Glu Leu Ile Gln Arg Asn Leu Ser Pro Ala Leu Gly Gln Met Pro
                1220                1225                1230

 Ile Ser Pro Asp Leu Ser His Thr Thr Leu Ser Pro Asp Leu Ser
                1235                1240                1245

 His Thr Thr Leu Ser Leu Asp Leu Ser Gln Thr Asn Leu Ser Pro
                1250                1255                1260

 Glu Leu Ser Gln Thr Asn Leu Ser Pro Ala Leu Gly Gln Met Pro
                1265                1270                1275

 Leu Ser Pro Asp Leu Ser His Thr Thr Ile Ser Leu Asp Phe Ser
                1280                1285                1290

 Gln Thr Asn Leu Ser Pro Glu Leu Ser His Met Thr Leu Ser Pro
                1295                1300                1305

 Glu Leu Ser Gln Thr Asn Leu Ser Pro Ala Leu Gly Gln Met Pro
                1310                1315                1320

 Ile Ser Pro Asp Leu Ser His Thr Thr Leu Ser Leu Asp Phe Ser
                1325                1330                1335

 Gln Thr Asn Leu Ser Pro Glu Leu Ser Gln Thr Asn Leu Ser Pro
                1340                1345                1350

 Ala Leu Gly Gln Met Pro Leu Ser Pro Asp Pro Ser His Thr Thr
                1355                1360                1365

 Leu Ser Leu Asp Leu Ser Gln Thr Asn Leu Ser Pro Glu Leu Ser
                1370                1375                1380

 Gln Thr Asn Leu Ser Pro Asp Leu Ser Glu Met Pro Leu Phe Ala
                1385                1390                1395

 Asp Leu Ser Gln Ile Pro Leu Thr Pro Asp Leu Asp Gln Met Thr
                1400                1405                1410

 Leu Ser Pro Asp Leu Gly Glu Thr Asp Leu Ser Pro Asn Phe Gly
                1415                1420                1425

 Gln Met Ser Leu Ser Pro Asp Leu Ser Gln Val Thr Leu Ser Pro
                1430                1435                1440

 Asp Ile Ser Asp Thr Thr Leu Leu Pro Asp Leu Ser Gln Ile Ser
                1445                1450                1455

 Pro Pro Pro Asp Leu Asp Gln Ile Phe Tyr Pro Ser Glu Ser Ser
                1460                1465                1470

 Gln Ser Leu Leu Leu Gln Glu Phe Asn Glu Ser Phe Pro Tyr Pro
                1475                1480                1485

 Asp Leu Gly Gln Met Pro Ser Pro Ser Ser Pro Thr Leu Asn Asp
                1490                1495                1500

 Thr Phe Leu Ser Lys Glu Phe Asn Pro Leu Val Ile Val Gly Leu
                1505                1510                1515

 Ser Lys Asp Gly Thr Asp Tyr Ile Glu Ile Ile Pro Lys Glu Glu
                1520                1525                1530

 Val Gln Ser Ser Glu Asp Asp Tyr Ala Glu Ile Asp Tyr Val Pro
                1535                1540                1545

 Tyr Asp Asp Pro Tyr Lys Thr Asp Val Arg Thr Asn Ile Asn Ser
                1550                1555                1560

 Ser Arg Asp Pro Asp Asn Ile Ala Ala Trp Tyr Leu Arg Ser Asn
                1565                1570                1575

 Asn Gly Asn Arg Arg Asn Tyr Tyr Ile Ala Ala Glu Glu Ile Ser
                1580                1585                1590

 Trp Asp Tyr Ser Glu Phe Val Gln Arg Glu Thr Asp Ile Glu Asp
                1595                1600                1605

 Ser Asp Asp Ile Pro Glu Asp Thr Thr Tyr Lys Lys Val Val Phe
                1610                1615                1620

 Arg Lys Tyr Leu Asp Ser Thr Phe Thr Lys Arg Asp Pro Arg Gly
                1625                1630                1635

 Glu Tyr Glu Glu His Leu Gly Ile Leu Gly Pro Ile Ile Arg Ala
                1640                1645                1650

 Glu Val Asp Asp Val Ile Gln Val Arg Phe Lys Asn Leu Ala Ser
                1655                1660                1665

 Arg Pro Tyr Ser Leu His Ala His Gly Leu Ser Tyr Glu Lys Ser
                1670                1675                1680

 Ser Glu Gly Lys Thr Tyr Glu Asp Asp Ser Pro Glu Trp Phe Lys
                1685                1690                1695

 Glu Asp Asn Ala Val Gln Pro Asn Ser Ser Tyr Thr Tyr Val Trp
                1700                1705                1710

 His Ala Thr Glu Arg Ser Gly Pro Glu Ser Pro Gly Ser Ala Cys
                1715                1720                1725

 Arg Ala Trp Ala Tyr Tyr Ser Ala Val Asn Pro Glu Lys Asp Ile
                1730                1735                1740

 His Ser Gly Leu Ile Gly Pro Leu Leu Ile Cys Gln Lys Gly Ile
                1745                1750                1755

 Leu His Lys Asp Ser Asn Met Pro Val Asp Met Arg Glu Phe Val
                1760                1765                1770

 Leu Leu Phe Met Thr Phe Asp Glu Lys Lys Ser Trp Tyr Tyr Glu
                1775                1780                1785

 Lys Lys Ser Arg Ser Ser Trp Arg Leu Thr Ser Ser Glu Met Lys
                1790                1795                1800

 Lys Ser His Glu Phe His Ala Ile Asn Gly Met Ile Tyr Ser Leu
                1805                1810                1815

 Pro Gly Leu Lys Met Tyr Glu Gln Glu Trp Val Arg Leu His Leu
                1820                1825                1830

 Leu Asn Ile Gly Gly Ser Gln Asp Ile His Val Val His Phe His
                1835                1840                1845

 Gly Gln Thr Leu Leu Glu Asn Gly Asn Lys Gln His Gln Leu Gly
                1850                1855                1860

 Val Trp Pro Leu Leu Pro Gly Ser Phe Lys Thr Leu Glu Met Lys
                1865                1870                1875

 Ala Ser Lys Pro Gly Trp Trp Leu Leu Asn Thr Glu Val Gly Glu
                1880                1885                1890

 Asn Gln Arg Ala Gly Met Gln Thr Pro Phe Leu Ile Met Asp Arg
                1895                1900                1905

 Asp Cys Arg Met Pro Met Gly Leu Ser Thr Gly Ile Ile Ser Asp
                1910                1915                1920

 Ser Gln Ile Lys Ala Ser Glu Phe Leu Gly Tyr Trp Glu Pro Arg
                1925                1930                1935

 Leu Ala Arg Leu Asn Asn Gly Gly Ser Tyr Asn Ala Trp Ser Val
                1940                1945                1950

 Glu Lys Leu Ala Ala Glu Phe Ala Ser Lys Pro Trp Ile Gln Val
                1955                1960                1965

 Asp Met Gln Lys Glu Val Ile Ile Thr Gly Ile Gln Thr Gln Gly
                1970                1975                1980

 Ala Lys His Tyr Leu Lys Ser Cys Tyr Thr Thr Glu Phe Tyr Val
                1985                1990                1995

 Ala Tyr Ser Ser Asn
                2000

<210> 1189
<211> 5747
<212> DNA
<213> Homo sapien

<400> 1189
 cgcacaccga cttgcatgca attatcatag cccgagtgct cctccgttga 50

 gagacttcgc ccccgagacc gctgactgtg aatgacaaat caaaagtcag 100

 ggttgcagaa tcagccggac tttcctgctc atttgcagca gagggaggaa 150

 gcagagaatg aaagattctg aaaataaagg tgcctcatct ccagacatgg 200

 agcccagcta tgggggaggt ctctttgaca tggtaaaagg aggtgcaggg 250

 aggctcttta gtaacctaaa ggacaacttg aaagacaccc tcaaagacac 300

 atcttctaga gtgatacaat ctgtgaccag ctacacaaag ggagatttag 350

 acttcactta tgttacctcc agaattattg tgatgtcctt tcctctggac 400

 aatgttgaca taggattcag gaatcaggtt gatgacattc gaagcttttt 450

 ggattccaga catcttgacc actacacagt atacaatctg tcacctaagt 500

 cttatcgaac tgccaagttt cacagccggg tctcagaatg cagttggccc 550

 attaggcagg ctcccagtct gcacaacctt tttgctgtgt gtcggaatat 600

 gtataactgg ctactgcaga atcccaaaaa tgtctgtgtt gtccactgct 650

 tggatggacg ggcggcatca tcaattctgg ttggtgctat gttcattttc 700

 tgtaatctct actctactcc tggcccagcc attcgattgc tatatgcaaa 750

 gcgaccagga attggacttt caccatccca taggagatac ctgggctata 800

 tgtgtgacct actggcagac aagccctacc gccctcactt caagcctctc 850

 acaattaagt cgatcactgt cagtccaata ccctttttca acaaacagag 900

 gaatggatgt cgcccttact gtgatgtact cattggagaa accaaaatat 950

 attcgacttg cacagatttt gaacgaatga aagaatatcg tgtccaagat 1000

 ggaaaaatct tcattccctt gaacatcact gtgcaaggag acgtggttgt 1050

 ttccatgtat cacttgaggt caaccattgg gagccggcta caggctaagg 1100

 tgaccaacac acagatattc cagcttcagt ttcacactgg attcatacca 1150

 ctggacacaa cagttttaaa gttcaccaag cctgagttag atgcatgtga 1200

 tgtaccagaa aaatatcctc agctatttca ggtgacactg gatgtagaac 1250

 tacagcccca tgacaaagta atagacttaa ctccaccatg ggaacattac 1300

 tgcacaaaag atgtcaatcc cagcatcctc ttctcttctc accaggaaca 1350

 tcaagatacg ctggccttag gaggacaggc tccaatagat atccctccag 1400

 acaaccccag gcattacgga caaagtggtt tctttgcctc tctctgttgg 1450

 caagatcaga aatcggagaa gtcattctgt gaggaagacc acgctgccct 1500

 agtgaatcag gaaagtgagc aatcagatga tgaacttctg acactttcca 1550

 gtccgcatgg caatgccaat ggtgacaagc ctcatggagt caagaagccc 1600

 agcaaaaagc agcaggagcc agcagcccct ccaccccctg aggatgtgga 1650

 ccttttgggc ctggaagggt ctgcaatgag taacagcttc tctccgccag 1700

 cggctcctcc caccaattct gaactactga gtgacctgtt tgggggtgga 1750

 ggtgcagctg gtcccaccca ggctggacag tcaggagtgg aagatgtgtt 1800

 tcatcctagt ggacctgcgt ctacccagtc aacaccacgc cgctctgcca 1850

 cctccacctc tgcgtctcca accctaagag tgggagaagg tgccaccttt 1900

 gacccatttg gagcaccttc taaaccatca ggtcaggatt tgctgggttc 1950

 ttttctgaac acatccagtg cttccagtga cccctttctc cagcccacaa 2000

 gaagtccttc gcccacagta catgcttcta gtacgcctgc tgtgaacatt 2050

 cagccagatg tttctggagg ttgggactgg catgctaaac caggaggctt 2100

 tggaatggga agcaagtcag ctgccaccag cccaaccgga tcctcgcatg 2150

 gtactcccac ccatcaaagc aaaccccaga ctctggatcc ttttgccgac 2200

 cttgggacac taggtagttc ttcctttgcc agcaaaccca ccacaccaac 2250

 tggattgggt ggaggattcc cgcctctcag ctcgccacag aaggcgtctc 2300

 cccagcctat gggtggcggg tggcagcagg gaggtgccta caactggcag 2350

 cagccacagc ctaagcctca gcccagcatg ccccactcct ctccccagaa 2400

 ccgacccaac tacaacgtga gcttctcagc catgcctggg ggccagaacg 2450

 aacgtgggaa aggatcaagt aatttggaag ggaaacaaaa agcagctgat 2500

 tttgaagacc tactctctgg tcaaggtttc aatgctcaca aagacaaaaa 2550

 ggggcctcgg acaatagctg agatgagaaa ggaggaaatg gccaaggaaa 2600

 tggatcctga gaaattaaag attctggaat ggattgaagg caaagaaaga 2650

 aatatcagag cccttctttc cacgatgcat accgtactat gggctgggga 2700

 gaccaagtgg aaaccagttg gcatggcaga cctggtaaca ccagagcagg 2750

 tgaagaaggt gtacaggaag gctgtcctgg tggtgcaccc agataaagct 2800

 actgggcaac cctatgaaca atacgcaaag atgattttca tggagctcaa 2850

 tgatgcctgg tctgaatttg aaaaccaagg ccaaaagccc ttatattaat 2900

 ttatgagctt ttccatctct gctgcagacc tgtgctaatg cttagtgtgt 2950

 gtcacaattc tgaggttttc gcagatgaac caaaaactcc agtaacatgt 3000

 tttcagtact aaaccgttaa gttactcatg aattaatttc tcattgataa 3050

 ggaatgtgga tgtttggttt ctccaaagtt cccaccataa aagatccaaa 3100

 gcatgagagg aacttctagt cagatgacct tgcagaacca ccgcattcca 3150

 ccctgccctt tggggagcct actcagcatt ctacctgggg aaatggaaaa 3200

 cagaggccac cacccatgaa ggcataacac ccatcacatt gtctgagaat 3250

 aggattaatg agcaaaagtt atgataatag agttatatga tggtttaatg 3300

 gtttctagat ttttcttgga aagatataat ttgagcagtg gctttatgca 3350

 gactccaaga acaaaaccac caggtatttt tttttaagta aaaatttact 3400

 aaggccttta gcataatact gtaaatgtct tttggtcaag aggactaaca 3450

 aatataaagg aacttgaaat gtggggagtg ataatagtcc agtgattaaa 3500

 ctacagtcca gtgattacca ccaactttct gactaagcta aaaatgaatg 3550

 aaaatggtgg ctaaagaaaa tagggactct gaagacgtcg aaatctttat 3600

 tcctggttag gaaggtgggc cgctaccctt ctttcccttt agaaaactgt 3650

 gattaattaa ataaaaagtc ttactactat aacaactcta aacctggttt 3700

 aaatgaaaca tctaattttg ctgtaaggct taatgctctt cttttgttta 3750

 gccaagaaaa cattcttagt tggaaacagg tggtaaagta gtttggcctg 3800

 ttcacaactt atcaggacca atatctagtg tggactcagt gttctctagg 3850

 tttgtgagca gttgtggtaa gagaatggaa ggcaacactg aataggagtt 3900

 aagggaatgg cacgatcaca gtgagagagc tgcactcacc tgcagaccca 3950

 gtcagatggc ttgtcagtat ctgctctgag gaaccaggtc ccacctcccc 4000

 acaaggcaaa tctagaccca ttaaattatt acagtgggct tttttgtttt 4050

 aaaagtggtt ggggatccac aggaacgaca ttcatacagg gacatttgtg 4100

 aaagcaaagc aagaatgaat gctttcccga tctcagactg gctggattca 4150

 gatcagtgtg ttggctggtt ctcattttaa ggggtaagca gtttgctatt 4200

 ctgtgacttt agtagatctc ttttgtgtgc acatatacaa tgtgcattat 4250

 acatatatat taaatatatc cacaaagcag atgggcaaaa agattttcat 4300

 gctaatcttc aaaggttcat gctcaatatt gtgaaaagct tttaaaagtt 4350

 gttttgaaaa gacaatcatt ttttgttttt gttttaactt tcttgtggca 4400

 agctataccg gaaaagcggc atgtcaaaaa tactttaggt tctacataga 4450

 tctctttctc tcttttgttt tgtttgtttg tttgttaaag ttcattattt 4500

 attttacctt ttactgacaa tgtgaaactc gaagaaaatg ttctcttttt 4550

 aaatatacag tcataaactg ttcaaggtaa ccataacaaa ctaggtgtta 4600

 tttattaacg tattataaaa taatgtttga tccagtatgt gcttgtctta 4650

 tttaaaattg gaatgtgaga catgttgctg tgacctgttt ttctttctca 4700

 ttcacatttg tagatattgt gtgaactaca gtatataatg ataacaatta 4750

 aaaggatatt ctgtggatgt cacgtatttt gaaatgatag aactacatta 4800

 gctttgtatc atgtttggat aattcatcaa tgttcacagt ttaaaacatc 4850

 attaaacatt atgtaattac aatgagaaag aatcttactt aaatttggag 4900

 attttccccc acatctcttt tccggataca ttataattct ggacccctat 4950

 ttatctcaaa actcttaata tatgcagacc aacaggtctt tgcattcctt 5000

 ttaaataact ggttgtgaca aagcttgttg ttgatcagat tcactgtttc 5050

 atcatattta ttgtaatata ttttttgttt tgtaaatatg ttacaacaaa 5100

 atgtgattgg tctaaaatat ttgtaatgta tattaaaagg ttcaaaaata 5150

 tttgtataaa tctaagttat ttgggtactt gtaggaatac aatgaggagc 5200

 ttgaatgcca ccttctgaca tgatttactt ttaaggaaag ttatgaggag 5250

 agaatacaaa aagcatgcac caaaatgtaa tctgacagga tttctggatt 5300

 tatacgtaat cactcctgcc ccaacacaca cacacacaca cacacacaca 5350

 cacacacaca cacatgcacg cacacatgat tttgattatg ctacatgata 5400

 tatgtttcaa aaagaattag catagaaatc ctggtctcct agccaaaaaa 5450

 atcaaaggat tttcaaaaaa acgaatctgt atgttgaggc aaaaggattg 5500

 aacctggaag tctgggactt tatcatagaa acaaagtctc agatatttta 5550

 gttctttgga aacaaatgct gtaattcaaa agcatttgac ctgtcactgt 5600

 actatctaca tgtggaagaa tgttcaagtt gaatcctaat gccgtgaatg 5650

 aaacacagtc tgtgtaggga atgagcaaaa aagttgaatt ccaattgctt 5700

 tttggccttt tggctaaaat aaatgtagca tctaatttta tcagttt 5747

<210> 1190
<211> 913
<212> PRT
<213> Homo sapien

<400> 1190
 Met Lys Asp Ser Glu Asn Lys Gly Ala Ser Ser Pro Asp Met Glu
   1               5                  10                  15

 Pro Ser Tyr Gly Gly Gly Leu Phe Asp Met Val Lys Gly Gly Ala
                  20                  25                  30

 Gly Arg Leu Phe Ser Asn Leu Lys Asp Asn Leu Lys Asp Thr Leu
                  35                  40                  45

 Lys Asp Thr Ser Ser Arg Val Ile Gln Ser Val Thr Ser Tyr Thr
                  50                  55                  60

 Lys Gly Asp Leu Asp Phe Thr Tyr Val Thr Ser Arg Ile Ile Val
                  65                  70                  75

 Met Ser Phe Pro Leu Asp Asn Val Asp Ile Gly Phe Arg Asn Gln
                  80                  85                  90

 Val Asp Asp Ile Arg Ser Phe Leu Asp Ser Arg His Leu Asp His
                  95                 100                 105

 Tyr Thr Val Tyr Asn Leu Ser Pro Lys Ser Tyr Arg Thr Ala Lys
                 110                 115                 120

 Phe His Ser Arg Val Ser Glu Cys Ser Trp Pro Ile Arg Gln Ala
                 125                 130                 135

 Pro Ser Leu His Asn Leu Phe Ala Val Cys Arg Asn Met Tyr Asn
                 140                 145                 150

 Trp Leu Leu Gln Asn Pro Lys Asn Val Cys Val Val His Cys Leu
                 155                 160                 165

 Asp Gly Arg Ala Ala Ser Ser Ile Leu Val Gly Ala Met Phe Ile
                 170                 175                 180

 Phe Cys Asn Leu Tyr Ser Thr Pro Gly Pro Ala Ile Arg Leu Leu
                 185                 190                 195

 Tyr Ala Lys Arg Pro Gly Ile Gly Leu Ser Pro Ser His Arg Arg
                 200                 205                 210

 Tyr Leu Gly Tyr Met Cys Asp Leu Leu Ala Asp Lys Pro Tyr Arg
                 215                 220                 225

 Pro His Phe Lys Pro Leu Thr Ile Lys Ser Ile Thr Val Ser Pro
                 230                 235                 240

 Ile Pro Phe Phe Asn Lys Gln Arg Asn Gly Cys Arg Pro Tyr Cys
                 245                 250                 255

 Asp Val Leu Ile Gly Glu Thr Lys Ile Tyr Ser Thr Cys Thr Asp
                 260                 265                 270

 Phe Glu Arg Met Lys Glu Tyr Arg Val Gln Asp Gly Lys Ile Phe
                 275                 280                 285

 Ile Pro Leu Asn Ile Thr Val Gln Gly Asp Val Val Val Ser Met
                 290                 295                 300

 Tyr His Leu Arg Ser Thr Ile Gly Ser Arg Leu Gln Ala Lys Val
                 305                 310                 315

 Thr Asn Thr Gln Ile Phe Gln Leu Gln Phe His Thr Gly Phe Ile
                 320                 325                 330

 Pro Leu Asp Thr Thr Val Leu Lys Phe Thr Lys Pro Glu Leu Asp
                 335                 340                 345

 Ala Cys Asp Val Pro Glu Lys Tyr Pro Gln Leu Phe Gln Val Thr
                 350                 355                 360

 Leu Asp Val Glu Leu Gln Pro His Asp Lys Val Ile Asp Leu Thr
                 365                 370                 375

 Pro Pro Trp Glu His Tyr Cys Thr Lys Asp Val Asn Pro Ser Ile
                 380                 385                 390

 Leu Phe Ser Ser His Gln Glu His Gln Asp Thr Leu Ala Leu Gly
                 395                 400                 405

 Gly Gln Ala Pro Ile Asp Ile Pro Pro Asp Asn Pro Arg His Tyr
                 410                 415                 420

 Gly Gln Ser Gly Phe Phe Ala Ser Leu Cys Trp Gln Asp Gln Lys
                 425                 430                 435

 Ser Glu Lys Ser Phe Cys Glu Glu Asp His Ala Ala Leu Val Asn
                 440                 445                 450

 Gln Glu Ser Glu Gln Ser Asp Asp Glu Leu Leu Thr Leu Ser Ser
                 455                 460                 465

 Pro His Gly Asn Ala Asn Gly Asp Lys Pro His Gly Val Lys Lys
                 470                 475                 480

 Pro Ser Lys Lys Gln Gln Glu Pro Ala Ala Pro Pro Pro Pro Glu
                 485                 490                 495

 Asp Val Asp Leu Leu Gly Leu Glu Gly Ser Ala Met Ser Asn Ser
                 500                 505                 510

 Phe Ser Pro Pro Ala Ala Pro Pro Thr Asn Ser Glu Leu Leu Ser
                 515                 520                 525

 Asp Leu Phe Gly Gly Gly Gly Ala Ala Gly Pro Thr Gln Ala Gly
                 530                 535                 540

 Gln Ser Gly Val Glu Asp Val Phe His Pro Ser Gly Pro Ala Ser
                 545                 550                 555

 Thr Gln Ser Thr Pro Arg Arg Ser Ala Thr Ser Thr Ser Ala Ser
                 560                 565                 570

 Pro Thr Leu Arg Val Gly Glu Gly Ala Thr Phe Asp Pro Phe Gly
                 575                 580                 585

 Ala Pro Ser Lys Pro Ser Gly Gln Asp Leu Leu Gly Ser Phe Leu
                 590                 595                 600

 Asn Thr Ser Ser Ala Ser Ser Asp Pro Phe Leu Gln Pro Thr Arg
                 605                 610                 615

 Ser Pro Ser Pro Thr Val His Ala Ser Ser Thr Pro Ala Val Asn
                 620                 625                 630

 Ile Gln Pro Asp Val Ser Gly Gly Trp Asp Trp His Ala Lys Pro
                 635                 640                 645

 Gly Gly Phe Gly Met Gly Ser Lys Ser Ala Ala Thr Ser Pro Thr
                 650                 655                 660

 Gly Ser Ser His Gly Thr Pro Thr His Gln Ser Lys Pro Gln Thr
                 665                 670                 675

 Leu Asp Pro Phe Ala Asp Leu Gly Thr Leu Gly Ser Ser Ser Phe
                 680                 685                 690

 Ala Ser Lys Pro Thr Thr Pro Thr Gly Leu Gly Gly Gly Phe Pro
                 695                 700                 705

 Pro Leu Ser Ser Pro Gln Lys Ala Ser Pro Gln Pro Met Gly Gly
                 710                 715                 720

 Gly Trp Gln Gln Gly Gly Ala Tyr Asn Trp Gln Gln Pro Gln Pro
                 725                 730                 735

 Lys Pro Gln Pro Ser Met Pro His Ser Ser Pro Gln Asn Arg Pro
                 740                 745                 750

 Asn Tyr Asn Val Ser Phe Ser Ala Met Pro Gly Gly Gln Asn Glu
                 755                 760                 765

 Arg Gly Lys Gly Ser Ser Asn Leu Glu Gly Lys Gln Lys Ala Ala
                 770                 775                 780

 Asp Phe Glu Asp Leu Leu Ser Gly Gln Gly Phe Asn Ala His Lys
                 785                 790                 795

 Asp Lys Lys Gly Pro Arg Thr Ile Ala Glu Met Arg Lys Glu Glu
                 800                 805                 810

 Met Ala Lys Glu Met Asp Pro Glu Lys Leu Lys Ile Leu Glu Trp
                 815                 820                 825

 Ile Glu Gly Lys Glu Arg Asn Ile Arg Ala Leu Leu Ser Thr Met
                 830                 835                 840

 His Thr Val Leu Trp Ala Gly Glu Thr Lys Trp Lys Pro Val Gly
                 845                 850                 855

 Met Ala Asp Leu Val Thr Pro Glu Gln Val Lys Lys Val Tyr Arg
                 860                 865                 870

 Lys Ala Val Leu Val Val His Pro Asp Lys Ala Thr Gly Gln Pro
                 875                 880                 885

 Tyr Glu Gln Tyr Ala Lys Met Ile Phe Met Glu Leu Asn Asp Ala
                 890                 895                 900

 Trp Ser Glu Phe Glu Asn Gln Gly Gln Lys Pro Leu Tyr
                 905                 910

<210> 1191
<211> 1947
<212> DNA
<213> Homo sapien

<400> 1191
 ggcacgaggc caagagctac gcggcggcgg cggagcgcag gcctcgtgcc 50

 gttacggcca tcacggcggc cgcagtggcg tcctggagcc ctcctcagtg 100

 ctgaagctgc tgaaagatgg cagaagaagt ggtggtagta gccaaatttg 150

 attatgtggc ccaacaagaa caagagttgg acatcaagaa gaatgagaga 200

 ttatggcttc tggatgattc taagtcctgg tggcgagttc gaaattccat 250

 gaataaaaca ggttttgtgc cttctaacta tgtggaaagg aaaaacagtg 300

 ctcggaaagc atctattgtg aaaaacctaa aggatacctt aggcattgga 350

 aaagtgaaaa gaaaacctag tgtgccagat tctgcatctc ctgctgatga 400

 tagttttgtt gacccagggg aacgtctcta tgacctcaac atgcccgctt 450

 atgtgaaatt taactacatg gctgagagag aggatgaatt atcattgata 500

 aaggggacaa aggtgatcgt catggagaaa tgcagtgatg ggtggtggcg 550

 tggtagctac aatggacaag ttggatggtt cccttcaaac tatgtaactg 600

 aagaaggtga cagtcctttg ggtgaccatg tgggttctct gtcagagaaa 650

 ttagcagcag tcgtcaataa cctaaatact gggcaagtgt tgcatgtggt 700

 acaggctctt tacccattca gctcatctaa tgatgaagaa cttaatttcg 750

 agaaaggaga tgtaatggat gttattgaaa aacctgaaaa tgacccagag 800

 tggtggaaat gcaggaagat caatggtatg gttggtctag taccaaaaaa 850

 ctatgttacc gttatgcaga ataatccatt aacttcaggt ttggaaccat 900

 cacctccaca gtgtgattac attaggcctt cactcactgg aaagtttgct 950

 ggcaatcctt ggtattatgg caaagtcacc aggcatcaag cagaaatggc 1000

 attaaatgaa agaggacatg aaggggattt cctcattcgt gatagtgaat 1050

 cttcgccaaa tgatttctca gtatcactaa aagcacaagg gaaaaacaag 1100

 cattttaaag tccaactaaa agagactgtc tactgcattg ggcagcgtaa 1150

 attcagcacc atggaagaac ttgtagaaca ttacaaaaag gcaccaattt 1200

 ttacaagtga acaaggagaa aaattatatc ttgtcaagca tttatcatga 1250

 tactgctgac cagaagtgac tgctgtgtag ctgtaatttg tcatgtaatt 1300

 gaagactgag aaaatgttgg gtccagtcgt gcttgattgg aaattgttgt 1350

 ttctaaatct atatgagaat tgacaataag tatttttatt ataactcagc 1400

 ccatacatat atactatgta tgcagtgcat ctgcatagaa cagttcctta 1450

 tccttggcct tctgttttat tgtttttttc tttgctgttt tccctttgct 1500

 tctaatatta cagttttgta ttttgtaaac aaaaatcaaa taatgcatat 1550

 cagaatcttt atatggaaga aatcctttat tgcctttcct ttgtttcctt 1600

 gtaaaggcac cctgttctgt tatggttttt cattatataa aattattata 1650

 tctatatatg acatatgcta aaatttcttg gagagtgtta atcttttctg 1700

 tgactaaata gcaataataa gtggaaaatt agaaattatt tccaggtatt 1750

 atatttgtca caggccattg taaataccaa gtatattgtg tctgccataa 1800

 tttttaaaaa tacattcatt gtcttcagtc atacagcaag acacatgaga 1850

 catagattag aaaacatgtt gtacaatttt aatttacaac tgttggaaat 1900

 aaaaatcact taattttttt ccaaaaaaaa aaaaaaaaaa aaaaaaa 1947

<210> 1192
<211> 377
<212> PRT
<213> Homo sapien

<400> 1192
 Met Ala Glu Glu Val Val Val Val Ala Lys Phe Asp Tyr Val Ala
   1               5                  10                  15

 Gln Gln Glu Gln Glu Leu Asp Ile Lys Lys Asn Glu Arg Leu Trp
                  20                  25                  30

 Leu Leu Asp Asp Ser Lys Ser Trp Trp Arg Val Arg Asn Ser Met
                  35                  40                  45

 Asn Lys Thr Gly Phe Val Pro Ser Asn Tyr Val Glu Arg Lys Asn
                  50                  55                  60

 Ser Ala Arg Lys Ala Ser Ile Val Lys Asn Leu Lys Asp Thr Leu
                  65                  70                  75

 Gly Ile Gly Lys Val Lys Arg Lys Pro Ser Val Pro Asp Ser Ala
                  80                  85                  90

 Ser Pro Ala Asp Asp Ser Phe Val Asp Pro Gly Glu Arg Leu Tyr
                  95                 100                 105

 Asp Leu Asn Met Pro Ala Tyr Val Lys Phe Asn Tyr Met Ala Glu
                 110                 115                 120

 Arg Glu Asp Glu Leu Ser Leu Ile Lys Gly Thr Lys Val Ile Val
                 125                 130                 135

 Met Glu Lys Cys Ser Asp Gly Trp Trp Arg Gly Ser Tyr Asn Gly
                 140                 145                 150

 Gln Val Gly Trp Phe Pro Ser Asn Tyr Val Thr Glu Glu Gly Asp
                 155                 160                 165

 Ser Pro Leu Gly Asp His Val Gly Ser Leu Ser Glu Lys Leu Ala
                 170                 175                 180

 Ala Val Val Asn Asn Leu Asn Thr Gly Gln Val Leu His Val Val
                 185                 190                 195

 Gln Ala Leu Tyr Pro Phe Ser Ser Ser Asn Asp Glu Glu Leu Asn
                 200                 205                 210

 Phe Glu Lys Gly Asp Val Met Asp Val Ile Glu Lys Pro Glu Asn
                 215                 220                 225

 Asp Pro Glu Trp Trp Lys Cys Arg Lys Ile Asn Gly Met Val Gly
                 230                 235                 240

 Leu Val Pro Lys Asn Tyr Val Thr Val Met Gln Asn Asn Pro Leu
                 245                 250                 255

 Thr Ser Gly Leu Glu Pro Ser Pro Pro Gln Cys Asp Tyr Ile Arg
                 260                 265                 270

 Pro Ser Leu Thr Gly Lys Phe Ala Gly Asn Pro Trp Tyr Tyr Gly
                 275                 280                 285

 Lys Val Thr Arg His Gln Ala Glu Met Ala Leu Asn Glu Arg Gly
                 290                 295                 300

 His Glu Gly Asp Phe Leu Ile Arg Asp Ser Glu Ser Ser Pro Asn
                 305                 310                 315

 Asp Phe Ser Val Ser Leu Lys Ala Gln Gly Lys Asn Lys His Phe
                 320                 325                 330

 Lys Val Gln Leu Lys Glu Thr Val Tyr Cys Ile Gly Gln Arg Lys
                 335                 340                 345

 Phe Ser Thr Met Glu Glu Leu Val Glu His Tyr Lys Lys Ala Pro
                 350                 355                 360

 Ile Phe Thr Ser Glu Gln Gly Glu Lys Leu Tyr Leu Val Lys His
                 365                 370                 375

 Leu Ser


<210> 1193
<211> 4208
<212> DNA
<213> Homo sapien

<400> 1193
 tctttaagat ttgtagctac taagaaagaa aggagctttt tttccttggg 50

 ccttcaaact gaaagaaccg catgagcctg acggcgcatg gtcttaacat 100

 caggctgtgc aggaagaagc tatctgcaga tggatgccag cacacacaag 150

 gaagcagagc tctggcaaca ttgagtcaaa gcaaggacac aacatcagag 200

 ggacggcaga gaatccttgt gtgtagtctt tggtggcagt ttgaaaattg 250

 caaggaggga ctttaagact acttctgatt tgcaaagatg gtctgtgctc 300

 cgagcaggct aaagtgactg gacgagacgc actgttggag aaataaaaat 350

 gacttcccat tatgtgattg ccatctttgc cctgatgagc ttctgtttag 400

 ccactgcagg tccagagcct ggtgcactgt gtgaactgtc acctgtcagt 450

 gcctcccatc ctgtccaggc cttgatggag agcttcactg ttttgtcagg 500

 ctgtgccagc agaggcacaa ctgggctgcc acaggaggtg catgtcctga 550

 atctcgcact gcgccagggg cctggccagc tacagagaga ggtcacactt 600

 cacctgaatc ccatctcctc agtccacatc caccacaagt ctgttgtgtt 650

 cctgctcaac tccccacacc ccctggtgtg gcatctgaag acagagagac 700

 ttgccactgg ggtctccaga ctgtttttgg tgtctgaggg ttctgtggtc 750

 cagttttcat cagcaaactt ctccttgaca gcagaaacag aagaaaggaa 800

 cttcccccat ggaaatgaac atctgttaaa ttgggcccga aaagagtatg 850

 gagcagttac ttcattcacc gaactcaaga tagcaagaaa catttatatt 900

 aaagtggggg aagatcaagt gttccctcca aagtgcaaca tagggaagaa 950

 ttttctctca ctcaattacc ttgctgagta ccttcaaccc aaagcagcag 1000

 aagggtgtgt gatgtccagc cagccccaga atgaggaagt acacatcatc 1050

 gagctaatca cccccaactc taacccctac agtgctttcc aggtggatat 1100

 aacaattgat ataagacctt ctcaagagga tcttgaagtg gtcaaaaatc 1150

 tcatcctgat cttgaagtgc aaaaagtctg tcaactgggt gatcaaatct 1200

 tttgatgtta agggaagcct gaaaattatt gctcctaaca gtattggctt 1250

 tggaaaagag agtgaaagat ctatgacaat gaccaaatca ataagagatg 1300

 acattccttc aacccaaggg aatctggtga agtgggcttt ggacaatggc 1350

 tatagtccaa taacttcata cacaatggct cctgtggcaa tagtatttca 1400

 tcttcggctt gaaaataatg aggagatggg agatgaggaa gtccacacta 1450

 ttcctcctga gctacggatc ctgctggacc ctggtgccct gcctgccctg 1500

 cagaacccgc ccatccgggg aggggaaggc caaaatggag gccttccgtt 1550

 tcctttccca gatatttcca ggagagtctg gaatgaagag ggagaagatg 1600

 ggctccctcg gccaaaggac cctgtcattc ccagcataca actgtttcct 1650

 ggtctcagag agccagaaga ggtgcaaggg agcgtggata ttgccctgtc 1700

 tgtcaaatgt gacaatgaga agatgatcgt ggctgtagaa aaagattctt 1750

 ttcaggccag tggctactcg gggatggacg tcaccctgtt ggatcctacc 1800

 tgcaaggcca agatgaatgg cacacacttt gttttggagt ctcctctgaa 1850

 tggctgcggt actcggcccc ggtggtcagc ccttgatggt gtggtctact 1900

 ataactccat tgtgatacag gttccagccc ttggggacag tagtggttgg 1950

 ccagatggtt atgaagatct ggagtcaggt gataatggat ttccgggaga 2000

 tatggatgaa ggagatgctt ccctgttcac ccgacctgaa atcgtggtgt 2050

 ttaattgcag ccttcagcag gtgaggaacc ccagcagctt ccaggaacag 2100

 ccccacggaa acatcacctt caacatggag ctatacaaca ctgacctctt 2150

 tttggtgccc tcccagggcg tcttctctgt gccagagaat ggacacgttt 2200

 atgttgaggt atctgttact aaggctgaac aagaactggg atttgccatc 2250

 caaacgtgct ttatctctcc atattcgaac cctgatagga tgtctcatta 2300

 caccattatt gagaatattt gtcctaaaga tgaatctgtg aaattctaca 2350

 gtcccaagag agtgcacttc cctatcccgc aagctgacat ggataagaag 2400

 cgattcagct ttgtcttcaa gcctgtcttc aacacctcac tgctctttct 2450

 acagtgtgag ctgacgctgt gtacgaagat ggagaagcac ccccagaagt 2500

 tgcctaagtg tgtgcctcct gacgaagcct gcacctcgct ggacgcctcg 2550

 ataatctggg ccatgatgca gaataagaag acgttcacca agccccttgc 2600

 tgtgatccac catgaagcag aatctaaaga aaaaggtcca agcatgaagg 2650

 aaccaaatcc aatttctcca ccaattttcc atggtctgga caccctaacc 2700

 gtgatgggca ttgcgtttgc agcctttgtg atcggagcac tcctgacggg 2750

 ggccttgtgg tacatctatt ctcacacagg ggagacagca ggaaggcagc 2800

 aagtccccac ctccccgcca gcctcggaaa acagcagtgc tgcccacagc 2850

 atcggcagca cgcagagcac gccttgctcc agcagcagca cggcctagcc 2900

 caacccaggc ccaacccggc ccaacccagc ccagcccagc tcagctcagc 2950

 tactccaagg gcaggaccaa tggctgagcc tcgtgtccag actcagaggg 3000

 ctggattttg gttcccttgt aaagacagag tgaatttcag tataaagatc 3050

 acccgttgta ttcaccccac acccagggct agtataaaca tgaccctggg 3100

 cttctgtacc acactagaat tcatgtgaga aagctaaaat ggtggtcttc 3150

 tccaccagcc cctcacaggc ttgggggttt tctatgtgaa acacatgcca 3200

 gtttttaaaa tgctgctttg tccaggtgag aacatccata atttggggcc 3250

 ctgagtttta cccagactca aggagttggt aaagggttaa tagccagata 3300

 gtagaaccag tgaggagatg cggccaaaga ttctttatat ctgaaccaag 3350

 atgtaaaaca agaaatgctt tgaggctttc taagcgatcc tcctgtctaa 3400

 tttgcacctt tgtctggatg cactcttctg accttgctgc cacaacctgt 3450

 ggggtctgat gtgtcccaag atgggtgctg ccctcaggga ctgcaccctg 3500

 acaagtgtta aggcaacatt ccttgcttgt gccctgggcc aaaaccaatg 3550

 ctgatgacct tatcagcttc ctgtttcttc ccatactgca tacaccactg 3600

 caaaatgtct taatgcaaat tttgtatttc ttacaggcct acagaaattg 3650

 aaaatgacca aaatcaggaa ccacagattt gtgcccattc ctaatatttt 3700

 gttctgcaaa ttaatgtata atttgaggtg aaattcagtt ataaagtcaa 3750

 ggacgaattt gcacagtgat atatttctat gtgtatgcaa gtacaagtat 3800

 ataatatgtc acctggcaca ttcattttct cagttgaaga agagaaaatt 3850

 tgaaaatgtc cttatgcttt tagagttgca acttaagtat atttggtagg 3900

 gtgagtgttt ccactcaaaa tatgtcaact taaaaaaaaa taggcccttt 3950

 cataaaaacc aaactgtagc aagatgcaaa tgcatggcaa atctgtcggt 4000

 ctccagttgg ttatctgaat agtgtcacca attccaccaa gacagtgctg 4050

 agattggaaa gggcactcat ttggattgcc ttacttctct tgccttaaat 4100

 atatcccata tatttaatat gtcaaaaagg gcttgaggtg aatttcatta 4150

 aatggaataa tatgatgcca ctttgcagct aaaataagct cagtgatacc 4200

 tccttgtt 4208

<210> 1194
<211> 849
<212> PRT
<213> Homo sapien

<400> 1194
 Met Thr Ser His Tyr Val Ile Ala Ile Phe Ala Leu Met Ser Phe
   1               5                  10                  15

 Cys Leu Ala Thr Ala Gly Pro Glu Pro Gly Ala Leu Cys Glu Leu
                  20                  25                  30

 Ser Pro Val Ser Ala Ser His Pro Val Gln Ala Leu Met Glu Ser
                  35                  40                  45

 Phe Thr Val Leu Ser Gly Cys Ala Ser Arg Gly Thr Thr Gly Leu
                  50                  55                  60

 Pro Gln Glu Val His Val Leu Asn Leu Ala Leu Arg Gln Gly Pro
                  65                  70                  75

 Gly Gln Leu Gln Arg Glu Val Thr Leu His Leu Asn Pro Ile Ser
                  80                  85                  90

 Ser Val His Ile His His Lys Ser Val Val Phe Leu Leu Asn Ser
                  95                 100                 105

 Pro His Pro Leu Val Trp His Leu Lys Thr Glu Arg Leu Ala Thr
                 110                 115                 120

 Gly Val Ser Arg Leu Phe Leu Val Ser Glu Gly Ser Val Val Gln
                 125                 130                 135

 Phe Ser Ser Ala Asn Phe Ser Leu Thr Ala Glu Thr Glu Glu Arg
                 140                 145                 150

 Asn Phe Pro His Gly Asn Glu His Leu Leu Asn Trp Ala Arg Lys
                 155                 160                 165

 Glu Tyr Gly Ala Val Thr Ser Phe Thr Glu Leu Lys Ile Ala Arg
                 170                 175                 180

 Asn Ile Tyr Ile Lys Val Gly Glu Asp Gln Val Phe Pro Pro Lys
                 185                 190                 195

 Cys Asn Ile Gly Lys Asn Phe Leu Ser Leu Asn Tyr Leu Ala Glu
                 200                 205                 210

 Tyr Leu Gln Pro Lys Ala Ala Glu Gly Cys Val Met Ser Ser Gln
                 215                 220                 225

 Pro Gln Asn Glu Glu Val His Ile Ile Glu Leu Ile Thr Pro Asn
                 230                 235                 240

 Ser Asn Pro Tyr Ser Ala Phe Gln Val Asp Ile Thr Ile Asp Ile
                 245                 250                 255

 Arg Pro Ser Gln Glu Asp Leu Glu Val Val Lys Asn Leu Ile Leu
                 260                 265                 270

 Ile Leu Lys Cys Lys Lys Ser Val Asn Trp Val Ile Lys Ser Phe
                 275                 280                 285

 Asp Val Lys Gly Ser Leu Lys Ile Ile Ala Pro Asn Ser Ile Gly
                 290                 295                 300

 Phe Gly Lys Glu Ser Glu Arg Ser Met Thr Met Thr Lys Ser Ile
                 305                 310                 315

 Arg Asp Asp Ile Pro Ser Thr Gln Gly Asn Leu Val Lys Trp Ala
                 320                 325                 330

 Leu Asp Asn Gly Tyr Ser Pro Ile Thr Ser Tyr Thr Met Ala Pro
                 335                 340                 345

 Val Ala Ile Val Phe His Leu Arg Leu Glu Asn Asn Glu Glu Met
                 350                 355                 360

 Gly Asp Glu Glu Val His Thr Ile Pro Pro Glu Leu Arg Ile Leu
                 365                 370                 375

 Leu Asp Pro Gly Ala Leu Pro Ala Leu Gln Asn Pro Pro Ile Arg
                 380                 385                 390

 Gly Gly Glu Gly Gln Asn Gly Gly Leu Pro Phe Pro Phe Pro Asp
                 395                 400                 405

 Ile Ser Arg Arg Val Trp Asn Glu Glu Gly Glu Asp Gly Leu Pro
                 410                 415                 420

 Arg Pro Lys Asp Pro Val Ile Pro Ser Ile Gln Leu Phe Pro Gly
                 425                 430                 435

 Leu Arg Glu Pro Glu Glu Val Gln Gly Ser Val Asp Ile Ala Leu
                 440                 445                 450

 Ser Val Lys Cys Asp Asn Glu Lys Met Ile Val Ala Val Glu Lys
                 455                 460                 465

 Asp Ser Phe Gln Ala Ser Gly Tyr Ser Gly Met Asp Val Thr Leu
                 470                 475                 480

 Leu Asp Pro Thr Cys Lys Ala Lys Met Asn Gly Thr His Phe Val
                 485                 490                 495

 Leu Glu Ser Pro Leu Asn Gly Cys Gly Thr Arg Pro Arg Trp Ser
                 500                 505                 510

 Ala Leu Asp Gly Val Val Tyr Tyr Asn Ser Ile Val Ile Gln Val
                 515                 520                 525

 Pro Ala Leu Gly Asp Ser Ser Gly Trp Pro Asp Gly Tyr Glu Asp
                 530                 535                 540

 Leu Glu Ser Gly Asp Asn Gly Phe Pro Gly Asp Met Asp Glu Gly
                 545                 550                 555

 Asp Ala Ser Leu Phe Thr Arg Pro Glu Ile Val Val Phe Asn Cys
                 560                 565                 570

 Ser Leu Gln Gln Val Arg Asn Pro Ser Ser Phe Gln Glu Gln Pro
                 575                 580                 585

 His Gly Asn Ile Thr Phe Asn Met Glu Leu Tyr Asn Thr Asp Leu
                 590                 595                 600

 Phe Leu Val Pro Ser Gln Gly Val Phe Ser Val Pro Glu Asn Gly
                 605                 610                 615

 His Val Tyr Val Glu Val Ser Val Thr Lys Ala Glu Gln Glu Leu
                 620                 625                 630

 Gly Phe Ala Ile Gln Thr Cys Phe Ile Ser Pro Tyr Ser Asn Pro
                 635                 640                 645

 Asp Arg Met Ser His Tyr Thr Ile Ile Glu Asn Ile Cys Pro Lys
                 650                 655                 660

 Asp Glu Ser Val Lys Phe Tyr Ser Pro Lys Arg Val His Phe Pro
                 665                 670                 675

 Ile Pro Gln Ala Asp Met Asp Lys Lys Arg Phe Ser Phe Val Phe
                 680                 685                 690

 Lys Pro Val Phe Asn Thr Ser Leu Leu Phe Leu Gln Cys Glu Leu
                 695                 700                 705

 Thr Leu Cys Thr Lys Met Glu Lys His Pro Gln Lys Leu Pro Lys
                 710                 715                 720

 Cys Val Pro Pro Asp Glu Ala Cys Thr Ser Leu Asp Ala Ser Ile
                 725                 730                 735

 Ile Trp Ala Met Met Gln Asn Lys Lys Thr Phe Thr Lys Pro Leu
                 740                 745                 750

 Ala Val Ile His His Glu Ala Glu Ser Lys Glu Lys Gly Pro Ser
                 755                 760                 765

 Met Lys Glu Pro Asn Pro Ile Ser Pro Pro Ile Phe His Gly Leu
                 770                 775                 780

 Asp Thr Leu Thr Val Met Gly Ile Ala Phe Ala Ala Phe Val Ile
                 785                 790                 795

 Gly Ala Leu Leu Thr Gly Ala Leu Trp Tyr Ile Tyr Ser His Thr
                 800                 805                 810

 Gly Glu Thr Ala Gly Arg Gln Gln Val Pro Thr Ser Pro Pro Ala
                 815                 820                 825

 Ser Glu Asn Ser Ser Ala Ala His Ser Ile Gly Ser Thr Gln Ser
                 830                 835                 840

 Thr Pro Cys Ser Ser Ser Ser Thr Ala
                 845

<210> 1195
<211> 4255
<212> DNA
<213> Homo sapien

<400> 1195
 cagcctcctc ctgggaccct tgccctgccc ccctcccatg ggcacggacc 50

 ccccaccgcc tccacccact gccgcggggg ggcccgttgg ggcccagggc 100

 tggcgggcca tgtaaccagg gctgctgctg ggagcgcgga ggggaaggga 150

 gcccccagcc ctgctgggcc ggcccaggcc cctccgcggc tcccccttcc 200

 actacccacc tgcccggcac cccctcccca gtggttgtta accccgggac 250

 tccccaagcc cagcctctgt gtgcagcagc cccaggcggg ctaagtctcc 300

 aagatgccct tggtggattt cttctgcgag acctgctcta agccttggct 350

 ggtgggctgg tgggaccagt tcaaaaggat gttgaaccgt gagctcacac 400

 acctgtcaga aatgagcagg tccggaaacc aggtctcaga gtacatttcc 450

 acaacattcc tggacaaaca gaatgaagtg gagatcccat cacccacgat 500

 gaaggaacga gaaaaacagc aagcgccgcg accaagaccc tcccagccgc 550

 ccccgccccc tgtaccacac ttacagccca tgtcccaaat cacagggttg 600

 aaaaagttga tgcatagtaa cagcctgaac aactctaaca ttccccgatt 650

 tggggtgaag accgatcaag aagagctcct ggcccaagaa ctggagaacc 700

 tgaacaagtg gggcctgaac atcttttgcg tgtcggatta cgctggaggc 750

 cgctcactca cctgcatcat gtacatgata ttccaggagc gggacctgct 800

 gaagaaattc cgcatccctg tggacacgat ggtgacatac atgctgacgc 850

 tggaggatca ctaccacgct gacgtggcct accataacag cctgcacgca 900

 gctgacgtgc tgcagtccac ccacgtactg ctggccacgc ctgcactaga 950

 tgcagtgttc acggacctgg agattctcgc cgccctcttc gcggctgcca 1000

 tccacgatgt ggatcaccct ggggtctcca accagttcct catcaacacc 1050

 aattcggagc tggcgctcat gtacaacgat gagtcggtgc tcgagaatca 1100

 ccacctggcc gtgggcttca agctgctgca ggaggacaac tgcgacatct 1150

 tccagaacct cagcaagcgc cagcggcaga gcctacgcaa gatggtcatc 1200

 gacatggtgc tggccacgga catgtccaag cacatgaccc tcctggctga 1250

 cctgaagacc atggtggaga ccaagaaagt gaccagctca ggggtcctcc 1300

 tgctagataa ctactccgac cgcatccagg tcctccggaa catggtgcac 1350

 tgtgccgacc tcagcaaccc caccaagccg ctggagctgt accgccagtg 1400

 gacagaccgc atcatggccg agttcttcca gcagggtgac cgagagcgcg 1450

 agcgtggcat ggaaatcagc cccatgtgtg acaagcacac tgcctccgtg 1500

 gagaagtctc aggtgggttt tattgactac attgtgcacc cattgtggga 1550

 gacctgggcg gaccttgtcc acccagatgc ccaggagatc ttggacactt 1600

 tggaggacaa ccgggactgg tactacagcg ccatccggca gagcccatct 1650

 ccgccacccg aggaggagtc aagggggcca ggccacccac ccctgcctga 1700

 caagttccag tttgagctga cgctggagga ggaagaggag gaagaaatat 1750

 caatggccca gataccgtgc acagcccaag aggcattgac tgcgcaggga 1800

 ttgtcaggag tcgaggaagc tctggatgca accatagcct gggaggcatc 1850

 cccggcccag gagtcgttgg aagttatggc acaggaagca tccctggagg 1900

 ccgagctgga ggcagtgtat ttgacacagc aggcacagtc cacaggcagt 1950

 gcacctgtgg ctccggatga gttctcgtcc cgggaggaat tcgtggttgc 2000

 tgtaagccac agcagcccct ctgccctggc tcttcaaagc ccccttctcc 2050

 ctgcttggag gaccctgtct gtttcagagc atgccccggg cctcccgggc 2100

 ctcccctcca cggcggccga ggtggaggcc caacgagagc accaggctgc 2150

 caagagggct tgcagtgcct gcgcagggac atttggggag gacacatccg 2200

 cactcccagc tcctggtggc ggggggtcag gtggagaccc tacctgatcc 2250

 ccagacctct gtccctgttc ccctccactc ctcccctcac tcccctgctc 2300

 ccccgaccac ctcctcctct gcctcaaaga ctcttgtcct cttgtccctc 2350

 ctgagaaaaa agaaaacgaa aagtggggtt tttttctgtt ttcttttttt 2400

 cccctttccc cctgccccca cccacggggc ctttttttgg aggtgggggc 2450

 tggggaatga ggggctgagg tcccggaagg attttatttt tttgaatttt 2500

 aattgtaaca tttttagaaa aagaacaaaa aaagaaaaaa aaaagaaaga 2550

 aacacagcaa ctgtagatgc tcctgttcct ggttcccgct ttccacttcc 2600

 aaatccctcc cctcaccttc ccccactgcc ccccaagttc caggctcagt 2650

 cttccagccg cctggggagt ctctacctgg gcccaagcag gtgtggggcc 2700

 tccttctggg cttttcttct gaatttagag gatttctaga acgtggtcag 2750

 gaatagccat tctaggcggg gctggggcca gggtgggggg cagtcactgt 2800

 gggaggtccc agctccagcc cccctctggt ttgctgcctc ctctcccctc 2850

 taaaaaagtc ttccgcttga ttttgcacaa tcccggcgat actcctggcg 2900

 atactgacta gaaagtcagg gagctggggg agctgttcac tttaggatac 2950

 gggggtggta tggaagggag cgttcacacc gccagcctcg ggcctgggat 3000

 ttgaggaggg ccctagacct cctccactct ccatcccctt tcccttccac 3050

 tttgggttca ctttgaattt tctccgtttt ttggggcagt ggctctgatc 3100

 cactcacccc cccgcccccc gccccacttc tagctgcttc tcctcttgtt 3150

 tctgccttaa taattcccac ggccacaggc aagggggttg cagtggccgc 3200

 ctgcaccttg gatgaggcag ggccaggcgc ccagaacccc catcctggcc 3250

 gcacccccct ttccagggtc ctccggaccc caccttccac actctgatca 3300

 cagcccccct accttttgcc ctaggaggaa gcaataatgg tgtataccct 3350

 cattctcatt cctgggcagc ccttccttcc accctggcac caaaataatt 3400

 tctcctccat ccgtaccttg cctagcctct ccctctcccc cagctagtcc 3450

 cctgagcaat acggcagaca gatgcaagac catttttctc caagccatgg 3500

 gggactgttt ggaaggaaag ccccctctct ccctcctccc ctcgccctcg 3550

 gcctggttct gcagctggac cgacctcatt catcgcctgc cccctaccca 3600

 attctgagca cacggtactg tagcccccag ttcctcccta gccttccatc 3650

 cctctgtcca ccccaggggg aggtaacccc gcactcacac tcccttgatg 3700

 ctgtctgtac agggttcata ttttgtagcg aaagtcgttt ttgtcccagc 3750

 cggcgatcgg agtgggcctt ttctttcttt ttgttcattc tttacctttt 3800

 tttcttttct ttctttcttt tttgtacata ctgtaaggtt ggtttgtaaa 3850

 ttattctacg gaggcaaaaa gggaaaataa aaacttgccc ttccctggct 3900

 gacccagtcg ggaaggtagg gaaggaggtc tcccgttggg agagtctctg 3950

 ttcctgctgt attatacaac tgtaccatag tcctgggaaa agggtggact 4000

 caccgctgtt gttttatggg aagtcgtgtc atcctagggg ttggggctgg 4050

 gcagagcctg tcccctcccc ccttctccag gagccagggg gtgactggag 4100

 agacagaccc acccccaagc agggctcctc tccccagggt gagcacagga 4150

 cctctgtaag ctgcttgtgt attgtccact ttgacgatca gtcattcggt 4200

 ccgttgatca ataatccttc gatcttgtct ccaattaaac cgaggctttc 4250

 accga 4255

<210> 1196
<211> 647
<212> PRT
<213> Homo sapien

<400> 1196
 Met Pro Leu Val Asp Phe Phe Cys Glu Thr Cys Ser Lys Pro Trp
   1               5                  10                  15

 Leu Val Gly Trp Trp Asp Gln Phe Lys Arg Met Leu Asn Arg Glu
                  20                  25                  30

 Leu Thr His Leu Ser Glu Met Ser Arg Ser Gly Asn Gln Val Ser
                  35                  40                  45

 Glu Tyr Ile Ser Thr Thr Phe Leu Asp Lys Gln Asn Glu Val Glu
                  50                  55                  60

 Ile Pro Ser Pro Thr Met Lys Glu Arg Glu Lys Gln Gln Ala Pro
                  65                  70                  75

 Arg Pro Arg Pro Ser Gln Pro Pro Pro Pro Pro Val Pro His Leu
                  80                  85                  90

 Gln Pro Met Ser Gln Ile Thr Gly Leu Lys Lys Leu Met His Ser
                  95                 100                 105

 Asn Ser Leu Asn Asn Ser Asn Ile Pro Arg Phe Gly Val Lys Thr
                 110                 115                 120

 Asp Gln Glu Glu Leu Leu Ala Gln Glu Leu Glu Asn Leu Asn Lys
                 125                 130                 135

 Trp Gly Leu Asn Ile Phe Cys Val Ser Asp Tyr Ala Gly Gly Arg
                 140                 145                 150

 Ser Leu Thr Cys Ile Met Tyr Met Ile Phe Gln Glu Arg Asp Leu
                 155                 160                 165

 Leu Lys Lys Phe Arg Ile Pro Val Asp Thr Met Val Thr Tyr Met
                 170                 175                 180

 Leu Thr Leu Glu Asp His Tyr His Ala Asp Val Ala Tyr His Asn
                 185                 190                 195

 Ser Leu His Ala Ala Asp Val Leu Gln Ser Thr His Val Leu Leu
                 200                 205                 210

 Ala Thr Pro Ala Leu Asp Ala Val Phe Thr Asp Leu Glu Ile Leu
                 215                 220                 225

 Ala Ala Leu Phe Ala Ala Ala Ile His Asp Val Asp His Pro Gly
                 230                 235                 240

 Val Ser Asn Gln Phe Leu Ile Asn Thr Asn Ser Glu Leu Ala Leu
                 245                 250                 255

 Met Tyr Asn Asp Glu Ser Val Leu Glu Asn His His Leu Ala Val
                 260                 265                 270

 Gly Phe Lys Leu Leu Gln Glu Asp Asn Cys Asp Ile Phe Gln Asn
                 275                 280                 285

 Leu Ser Lys Arg Gln Arg Gln Ser Leu Arg Lys Met Val Ile Asp
                 290                 295                 300

 Met Val Leu Ala Thr Asp Met Ser Lys His Met Thr Leu Leu Ala
                 305                 310                 315

 Asp Leu Lys Thr Met Val Glu Thr Lys Lys Val Thr Ser Ser Gly
                 320                 325                 330

 Val Leu Leu Leu Asp Asn Tyr Ser Asp Arg Ile Gln Val Leu Arg
                 335                 340                 345

 Asn Met Val His Cys Ala Asp Leu Ser Asn Pro Thr Lys Pro Leu
                 350                 355                 360

 Glu Leu Tyr Arg Gln Trp Thr Asp Arg Ile Met Ala Glu Phe Phe
                 365                 370                 375

 Gln Gln Gly Asp Arg Glu Arg Glu Arg Gly Met Glu Ile Ser Pro
                 380                 385                 390

 Met Cys Asp Lys His Thr Ala Ser Val Glu Lys Ser Gln Val Gly
                 395                 400                 405

 Phe Ile Asp Tyr Ile Val His Pro Leu Trp Glu Thr Trp Ala Asp
                 410                 415                 420

 Leu Val His Pro Asp Ala Gln Glu Ile Leu Asp Thr Leu Glu Asp
                 425                 430                 435

 Asn Arg Asp Trp Tyr Tyr Ser Ala Ile Arg Gln Ser Pro Ser Pro
                 440                 445                 450

 Pro Pro Glu Glu Glu Ser Arg Gly Pro Gly His Pro Pro Leu Pro
                 455                 460                 465

 Asp Lys Phe Gln Phe Glu Leu Thr Leu Glu Glu Glu Glu Glu Glu
                 470                 475                 480

 Glu Ile Ser Met Ala Gln Ile Pro Cys Thr Ala Gln Glu Ala Leu
                 485                 490                 495

 Thr Ala Gln Gly Leu Ser Gly Val Glu Glu Ala Leu Asp Ala Thr
                 500                 505                 510

 Ile Ala Trp Glu Ala Ser Pro Ala Gln Glu Ser Leu Glu Val Met
                 515                 520                 525

 Ala Gln Glu Ala Ser Leu Glu Ala Glu Leu Glu Ala Val Tyr Leu
                 530                 535                 540

 Thr Gln Gln Ala Gln Ser Thr Gly Ser Ala Pro Val Ala Pro Asp
                 545                 550                 555

 Glu Phe Ser Ser Arg Glu Glu Phe Val Val Ala Val Ser His Ser
                 560                 565                 570

 Ser Pro Ser Ala Leu Ala Leu Gln Ser Pro Leu Leu Pro Ala Trp
                 575                 580                 585

 Arg Thr Leu Ser Val Ser Glu His Ala Pro Gly Leu Pro Gly Leu
                 590                 595                 600

 Pro Ser Thr Ala Ala Glu Val Glu Ala Gln Arg Glu His Gln Ala
                 605                 610                 615

 Ala Lys Arg Ala Cys Ser Ala Cys Ala Gly Thr Phe Gly Glu Asp
                 620                 625                 630

 Thr Ser Ala Leu Pro Ala Pro Gly Gly Gly Gly Ser Gly Gly Asp
                 635                 640                 645

 Pro Thr


<210> 1197
<211> 4508
<212> DNA
<213> Homo sapien

<400> 1197
 cgggcagcgt ggaccccgga tgagttgctt ttaggcttgc tggcccgcgg 50

 ggctgtccag gcacgcgagg cccctcaggt acgccctctc ttccctgcag 100

 gatccggccc tcaaagacga gggtcacgca cgcgttacaa ccccgaaaca 150

 gtagcacaag atttaatttt taaaagagcg tgtttcttcg gggcttgccg 200

 ttcgttcgtt tccagcctca ggaatttatg gtcgcctttt tgaatgagca 250

 acaaaatgct tcaacaagtt ccagaaaaca taaattttcc tgctgaagaa 300

 gagaaaatct tggagttttg gactgaattt aattgttttc aggaatgctt 350

 aaagcaatca aaacataaac caaaatttac cttctatgat ggtcctcctt 400

 ttgcaactgg actgcctcac tatggacata tacttgcggg tacaattaaa 450

 gatatagtta caagatatgc tcaccagagt gggtttcatg ttgacagaag 500

 atttggatgg gattgccatg gcttacctgt ggaatatgaa attgataaga 550

 cactgggaat cagaggacca gaggatgtgg ccaaaatggg gattacagag 600

 tataacaatc agtgccgagc aattgtgatg agatattctg ctgagtggaa 650

 gtctactgtt agcagacttg gccgatggat tgactttgac aatgactata 700

 aaactctgta tccacaattc atggaatcag tctggtgggt cttcaaacaa 750

 ctctatgata aaggccttgt ttatagaggt gtgaaagtca tgcccttctc 800

 tacggcatgt aacactccac tttccaactt cgagtcacac cagaattata 850

 aggatgttca agatccttca gtatttgtaa ctttcccttt ggaagaagat 900

 gaaactgtat ctttagttgc ttggacaacc actccctgga ctctacctag 950

 taaccttgct gtgtgtgtta atccagaaat gcaatatgtg aaaattaaag 1000

 atgttgccag aggacgatta ctcattttaa tggaagccag attgtcagcc 1050

 ctctataaat tggagagtga ctatgagatc cttgaaagat ttcctggtgc 1100

 ctatcttaaa ggcaagaagt acaggcccct gtttgactat ttcctgaagt 1150

 gtaaagagaa tggcgctttc actgtgcttg ttgacaacta tgtgaaggaa 1200

 gaagaaggca caggggttgt ccaccaagct ccttacttcg gtgctgagga 1250

 ctatcgggtc tgtatggact ttaacattat tcggaaagac tcactccctg 1300

 tttgccctgt ggatgcttca ggctgcttca caacggaggt gacagatttc 1350

 gcaggacagt atgtgaagga tgctgacaaa agtatcatca ggactttgaa 1400

 ggaacaaggc cgacttctgg ttgccaccac cttcactcac agctaccctt 1450

 tttgctggag atcagacact cctctaattt acaaagcagt gcccagctgg 1500

 tttgtgcgag tggagaacat ggtggaccag ctcctaagga acaatgacct 1550

 gtgctactgg gtcccagagt tggtacgaga aaaacgattt ggaaattggc 1600

 tgaaagatgc acgtgactgg acaatttcca gaaacagata ctggggcacc 1650

 cccatcccac tgtgggtcag cgatgacttt gaggaggtgg tatgcattgg 1700

 gtcagtggcg gaacttgaag aactgtcagg agcaaagatc tcagatctcc 1750

 acagagagag tgttgaccac ctgaccattc cttcacgctg tgggaaggga 1800

 tccttgcacc gcatctctga agtgtttgac tgttggtttg agagtggcag 1850

 catgccctat gctcaggttc attacccgtt tgaaaacaag agggagtttg 1900

 aggatgcttt tcctgcagat ttcattgccg agggcatcga ccaaaccaga 1950

 ggatggtttt ataccctgct ggtgctggcc acggccctct ttggacaacc 2000

 gcctttcaag aacgtaattg tgaatgggct tgtcctggca agtgatggcc 2050

 aaaaaatgag caaacggaaa aagaattatc cagatccagt ttccatcatc 2100

 cagaagtatg gtgctgatgc cctcagatta tatctgatta actcccctgt 2150

 ggtgagagca gaaaacctcc gctttaaaga agagggtgtg cgggacgtcc 2200

 ttaaggatgt actgctccca tggtacaatg cctatcgctt cttaatccag 2250

 aacgttctga ggctccagaa ggaggaagaa atagaatttc tctacaatga 2300

 gaacacggtt agagaaagcc ccaacattac agaccggtgg atcctgtcct 2350

 tcatgcagtc tctcattggc ttctttgaga ctgaaatggc agcttatagg 2400

 ctttatactg tggtgcctcg cctggtcaag tttgtagata ttctgaccaa 2450

 ttggtatgtt agaatgaacc gcagaagatt aaagggtgaa aatgggatgg 2500

 aggattgtgt catggcccta gaaaccttgt ttagtgttct gctttctctt 2550

 tgcagactta tagctcccta cacacctttt ctcactgaat tgatgtacca 2600

 gaatctaaag gtgctgattg accctgtttc tgttcaggac aaggacacac 2650

 tcagcattca ctacctcatg ctgccccgtg ttcgagaaga attgattgac 2700

 aagaaaacag agagtgcagt atctcagatg cagtctgtga ttgaacttgg 2750

 aagagtgatc agagaccgaa aaactattcc cataaagtat cctttgaaag 2800

 aaattgtggt tatccatcaa gatccagaag ctcttaaaga tatcaagtct 2850

 ttggagaagt atatcattga ggaactcaat gttcgaaaag ttacactgtc 2900

 tacagataaa aacaagtatg gcattcggct aagggcagaa ccagatcaca 2950

 tggtcctggg gaagcgtctg aagggagcct ttaaggcagt gatgacgtcc 3000

 atcaagcagt tgagcagtga ggagctggag cagttccaga agactgggac 3050

 cattgttgtg gaaggccatg aattgcacga tgaagacatc cgcctcatgt 3100

 acacctttga tcaggccaca ggtgggactg cgcaatttga agcacactca 3150

 gatgctcagg ctttggtcct cttagatgtc actcctgacc agtcaatggt 3200

 agatgaagga atggctcggg aagtcatcaa tcgcatacag aaacttcgca 3250

 aaaagtgcaa tctggttcca actgatgaaa tcacagtgta ctataaagca 3300

 aagtctgaag gaacatatct gaatagtgtt attgaaagcc acacagagtt 3350

 catatttacc accataaagg ctcccttgaa accatatcca gtttctccat 3400

 cggataaagt ccttattcaa gaaaaaacac agttgaaggg atctgaactg 3450

 gaaattacac tcaccagagg atcttccctt cctggtcctg cttgtgcata 3500

 tgtcaatctt aacatttgtg caaatggcag tgaacaaggt ggagtattgc 3550

 tcctggaaaa tccaaaaggt gacaataggt tggacctttt aaagctgaag 3600

 agtgttgtca ctagcatttt tggtgtgaaa aatacagagc tggctgtctt 3650

 ccatgatgaa acagaaatac aaaaccaaac tgacttactg agtcttagtg 3700

 gaaaaacact ttgtgtgact gcaggatcgg ctccctctct gatcaacagt 3750

 tctagtactc ttctttgtca gtatatcaac ctacagctcc tgaatgcaaa 3800

 gccacaagag tgtttaatgg ggacagtggg cactctcctg cttgaaaacc 3850

 cacttgggca gaatggactc acccaccaag gtcttctgta tgaagcagcc 3900

 aaggtgtttg gccttcggag caggaagcta aagctgtttc tgaatgagac 3950

 ccaaacgcag gaaattacag aagacatccc cgtgaagact ttgaatatga 4000

 agactgtgta tgtttctgtg ttaccaacaa cagcagactt ctagcatgta 4050

 cttatcaatg ttgttcggtc agcccttccc taattacacc tatcccctac 4100

 acatacatgc acatagacac acacatgaac acactgaaga tatttccttc 4150

 aggtgtgtgt aaaatatgct gcttggattg aaattcaaat gggattgatt 4200

 agtcaagtaa cttgagacct cacagtaatc ttcacactta accttagaca 4250

 cctatgcagt catgttggga gcaggttaca atgttacttc agcccacagt 4300

 ttatttctat tcttgagttc ttaagtacag aagatagaag tgatttaaat 4350

 ggcatagtat atatatcatt ttctggcctt ttaaaattta tttgagacct 4400

 cttgatgaaa tggacatatt atatatttct gccacctgga ttttcctgga 4450

 taatttgatg gaatatttta agtttcagta aatcagaaca ataaacaaac 4500

 tcagatat 4508

<210> 1198
<211> 1262
<212> PRT
<213> Homo sapien

<400> 1198
 Met Leu Gln Gln Val Pro Glu Asn Ile Asn Phe Pro Ala Glu Glu
   1               5                  10                  15

 Glu Lys Ile Leu Glu Phe Trp Thr Glu Phe Asn Cys Phe Gln Glu
                  20                  25                  30

 Cys Leu Lys Gln Ser Lys His Lys Pro Lys Phe Thr Phe Tyr Asp
                  35                  40                  45

 Gly Pro Pro Phe Ala Thr Gly Leu Pro His Tyr Gly His Ile Leu
                  50                  55                  60

 Ala Gly Thr Ile Lys Asp Ile Val Thr Arg Tyr Ala His Gln Ser
                  65                  70                  75

 Gly Phe His Val Asp Arg Arg Phe Gly Trp Asp Cys His Gly Leu
                  80                  85                  90

 Pro Val Glu Tyr Glu Ile Asp Lys Thr Leu Gly Ile Arg Gly Pro
                  95                 100                 105

 Glu Asp Val Ala Lys Met Gly Ile Thr Glu Tyr Asn Asn Gln Cys
                 110                 115                 120

 Arg Ala Ile Val Met Arg Tyr Ser Ala Glu Trp Lys Ser Thr Val
                 125                 130                 135

 Ser Arg Leu Gly Arg Trp Ile Asp Phe Asp Asn Asp Tyr Lys Thr
                 140                 145                 150

 Leu Tyr Pro Gln Phe Met Glu Ser Val Trp Trp Val Phe Lys Gln
                 155                 160                 165

 Leu Tyr Asp Lys Gly Leu Val Tyr Arg Gly Val Lys Val Met Pro
                 170                 175                 180

 Phe Ser Thr Ala Cys Asn Thr Pro Leu Ser Asn Phe Glu Ser His
                 185                 190                 195

 Gln Asn Tyr Lys Asp Val Gln Asp Pro Ser Val Phe Val Thr Phe
                 200                 205                 210

 Pro Leu Glu Glu Asp Glu Thr Val Ser Leu Val Ala Trp Thr Thr
                 215                 220                 225

 Thr Pro Trp Thr Leu Pro Ser Asn Leu Ala Val Cys Val Asn Pro
                 230                 235                 240

 Glu Met Gln Tyr Val Lys Ile Lys Asp Val Ala Arg Gly Arg Leu
                 245                 250                 255

 Leu Ile Leu Met Glu Ala Arg Leu Ser Ala Leu Tyr Lys Leu Glu
                 260                 265                 270

 Ser Asp Tyr Glu Ile Leu Glu Arg Phe Pro Gly Ala Tyr Leu Lys
                 275                 280                 285

 Gly Lys Lys Tyr Arg Pro Leu Phe Asp Tyr Phe Leu Lys Cys Lys
                 290                 295                 300

 Glu Asn Gly Ala Phe Thr Val Leu Val Asp Asn Tyr Val Lys Glu
                 305                 310                 315

 Glu Glu Gly Thr Gly Val Val His Gln Ala Pro Tyr Phe Gly Ala
                 320                 325                 330

 Glu Asp Tyr Arg Val Cys Met Asp Phe Asn Ile Ile Arg Lys Asp
                 335                 340                 345

 Ser Leu Pro Val Cys Pro Val Asp Ala Ser Gly Cys Phe Thr Thr
                 350                 355                 360

 Glu Val Thr Asp Phe Ala Gly Gln Tyr Val Lys Asp Ala Asp Lys
                 365                 370                 375

 Ser Ile Ile Arg Thr Leu Lys Glu Gln Gly Arg Leu Leu Val Ala
                 380                 385                 390

 Thr Thr Phe Thr His Ser Tyr Pro Phe Cys Trp Arg Ser Asp Thr
                 395                 400                 405

 Pro Leu Ile Tyr Lys Ala Val Pro Ser Trp Phe Val Arg Val Glu
                 410                 415                 420

 Asn Met Val Asp Gln Leu Leu Arg Asn Asn Asp Leu Cys Tyr Trp
                 425                 430                 435

 Val Pro Glu Leu Val Arg Glu Lys Arg Phe Gly Asn Trp Leu Lys
                 440                 445                 450

 Asp Ala Arg Asp Trp Thr Ile Ser Arg Asn Arg Tyr Trp Gly Thr
                 455                 460                 465

 Pro Ile Pro Leu Trp Val Ser Asp Asp Phe Glu Glu Val Val Cys
                 470                 475                 480

 Ile Gly Ser Val Ala Glu Leu Glu Glu Leu Ser Gly Ala Lys Ile
                 485                 490                 495

 Ser Asp Leu His Arg Glu Ser Val Asp His Leu Thr Ile Pro Ser
                 500                 505                 510

 Arg Cys Gly Lys Gly Ser Leu His Arg Ile Ser Glu Val Phe Asp
                 515                 520                 525

 Cys Trp Phe Glu Ser Gly Ser Met Pro Tyr Ala Gln Val His Tyr
                 530                 535                 540

 Pro Phe Glu Asn Lys Arg Glu Phe Glu Asp Ala Phe Pro Ala Asp
                 545                 550                 555

 Phe Ile Ala Glu Gly Ile Asp Gln Thr Arg Gly Trp Phe Tyr Thr
                 560                 565                 570

 Leu Leu Val Leu Ala Thr Ala Leu Phe Gly Gln Pro Pro Phe Lys
                 575                 580                 585

 Asn Val Ile Val Asn Gly Leu Val Leu Ala Ser Asp Gly Gln Lys
                 590                 595                 600

 Met Ser Lys Arg Lys Lys Asn Tyr Pro Asp Pro Val Ser Ile Ile
                 605                 610                 615

 Gln Lys Tyr Gly Ala Asp Ala Leu Arg Leu Tyr Leu Ile Asn Ser
                 620                 625                 630

 Pro Val Val Arg Ala Glu Asn Leu Arg Phe Lys Glu Glu Gly Val
                 635                 640                 645

 Arg Asp Val Leu Lys Asp Val Leu Leu Pro Trp Tyr Asn Ala Tyr
                 650                 655                 660

 Arg Phe Leu Ile Gln Asn Val Leu Arg Leu Gln Lys Glu Glu Glu
                 665                 670                 675

 Ile Glu Phe Leu Tyr Asn Glu Asn Thr Val Arg Glu Ser Pro Asn
                 680                 685                 690

 Ile Thr Asp Arg Trp Ile Leu Ser Phe Met Gln Ser Leu Ile Gly
                 695                 700                 705

 Phe Phe Glu Thr Glu Met Ala Ala Tyr Arg Leu Tyr Thr Val Val
                 710                 715                 720

 Pro Arg Leu Val Lys Phe Val Asp Ile Leu Thr Asn Trp Tyr Val
                 725                 730                 735

 Arg Met Asn Arg Arg Arg Leu Lys Gly Glu Asn Gly Met Glu Asp
                 740                 745                 750

 Cys Val Met Ala Leu Glu Thr Leu Phe Ser Val Leu Leu Ser Leu
                 755                 760                 765

 Cys Arg Leu Ile Ala Pro Tyr Thr Pro Phe Leu Thr Glu Leu Met
                 770                 775                 780

 Tyr Gln Asn Leu Lys Val Leu Ile Asp Pro Val Ser Val Gln Asp
                 785                 790                 795

 Lys Asp Thr Leu Ser Ile His Tyr Leu Met Leu Pro Arg Val Arg
                 800                 805                 810

 Glu Glu Leu Ile Asp Lys Lys Thr Glu Ser Ala Val Ser Gln Met
                 815                 820                 825

 Gln Ser Val Ile Glu Leu Gly Arg Val Ile Arg Asp Arg Lys Thr
                 830                 835                 840

 Ile Pro Ile Lys Tyr Pro Leu Lys Glu Ile Val Val Ile His Gln
                 845                 850                 855

 Asp Pro Glu Ala Leu Lys Asp Ile Lys Ser Leu Glu Lys Tyr Ile
                 860                 865                 870

 Ile Glu Glu Leu Asn Val Arg Lys Val Thr Leu Ser Thr Asp Lys
                 875                 880                 885

 Asn Lys Tyr Gly Ile Arg Leu Arg Ala Glu Pro Asp His Met Val
                 890                 895                 900

 Leu Gly Lys Arg Leu Lys Gly Ala Phe Lys Ala Val Met Thr Ser
                 905                 910                 915

 Ile Lys Gln Leu Ser Ser Glu Glu Leu Glu Gln Phe Gln Lys Thr
                 920                 925                 930

 Gly Thr Ile Val Val Glu Gly His Glu Leu His Asp Glu Asp Ile
                 935                 940                 945

 Arg Leu Met Tyr Thr Phe Asp Gln Ala Thr Gly Gly Thr Ala Gln
                 950                 955                 960

 Phe Glu Ala His Ser Asp Ala Gln Ala Leu Val Leu Leu Asp Val
                 965                 970                 975

 Thr Pro Asp Gln Ser Met Val Asp Glu Gly Met Ala Arg Glu Val
                 980                 985                 990

 Ile Asn Arg Ile Gln Lys Leu Arg Lys Lys Cys Asn Leu Val Pro
                 995                1000                1005

 Thr Asp Glu Ile Thr Val Tyr Tyr Lys Ala Lys Ser Glu Gly Thr
                1010                1015                1020

 Tyr Leu Asn Ser Val Ile Glu Ser His Thr Glu Phe Ile Phe Thr
                1025                1030                1035

 Thr Ile Lys Ala Pro Leu Lys Pro Tyr Pro Val Ser Pro Ser Asp
                1040                1045                1050

 Lys Val Leu Ile Gln Glu Lys Thr Gln Leu Lys Gly Ser Glu Leu
                1055                1060                1065

 Glu Ile Thr Leu Thr Arg Gly Ser Ser Leu Pro Gly Pro Ala Cys
                1070                1075                1080

 Ala Tyr Val Asn Leu Asn Ile Cys Ala Asn Gly Ser Glu Gln Gly
                1085                1090                1095

 Gly Val Leu Leu Leu Glu Asn Pro Lys Gly Asp Asn Arg Leu Asp
                1100                1105                1110

 Leu Leu Lys Leu Lys Ser Val Val Thr Ser Ile Phe Gly Val Lys
                1115                1120                1125

 Asn Thr Glu Leu Ala Val Phe His Asp Glu Thr Glu Ile Gln Asn
                1130                1135                1140

 Gln Thr Asp Leu Leu Ser Leu Ser Gly Lys Thr Leu Cys Val Thr
                1145                1150                1155

 Ala Gly Ser Ala Pro Ser Leu Ile Asn Ser Ser Ser Thr Leu Leu
                1160                1165                1170

 Cys Gln Tyr Ile Asn Leu Gln Leu Leu Asn Ala Lys Pro Gln Glu
                1175                1180                1185

 Cys Leu Met Gly Thr Val Gly Thr Leu Leu Leu Glu Asn Pro Leu
                1190                1195                1200

 Gly Gln Asn Gly Leu Thr His Gln Gly Leu Leu Tyr Glu Ala Ala
                1205                1210                1215

 Lys Val Phe Gly Leu Arg Ser Arg Lys Leu Lys Leu Phe Leu Asn
                1220                1225                1230

 Glu Thr Gln Thr Gln Glu Ile Thr Glu Asp Ile Pro Val Lys Thr
                1235                1240                1245

 Leu Asn Met Lys Thr Val Tyr Val Ser Val Leu Pro Thr Thr Ala
                1250                1255                1260

 Asp Phe


<210> 1199
<211> 396
<212> DNA
<213> Homo sapien

<400> 1199
 actccgcctt ccacgtgcac ccactgcctc ttcccttctc gcttgggaac 50

 tctagtctcg cctcgggttg caatggaccc caactgctcc tgtgccgctg 100

 gtgtctcctg cacctgcgcc agctcctgca agtgcaaaga gtgcaaatgc 150

 acctcctgca agaagagctg ctgctcctgc tgccctgtgg gctgtgccaa 200

 gtgtgcccaa ggctgcatct gcaaaggggc atcggagaag tgcagctgct 250

 gcgcctgatg tcgggacagc cctgctccca agtacaaata gagtgacccg 300

 taaaatctag gattttttgt tttttgctac aatcttgacc cctttgctac 350

 attccctttt ttctgtgaaa tatgtgaata ataattaaac acttag 396

<210> 1200
<211> 61
<212> PRT
<213> Homo sapien

<400> 1200
 Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Val Ser Cys Thr Cys
   1               5                  10                  15

 Ala Ser Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ala Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Ile Cys Lys Gly Ala Ser Glu Lys Cys Ser Cys Cys
                  50                  55                  60

 Ala


<210> 1201
<211> 1919
<212> DNA
<213> Homo sapien

<400> 1201
 ctgaagaaca aatcagcctg gtcaccagct tttcggaaca gcagagacac 50

 agagggcagt catgagtgag gtcaccaaga attccctgga gaaaatcctt 100

 ccacagctga aatgccattt cacctggaac ttattcaagg aagacagtgt 150

 ctcaagggat ctagaagata gagtgtgtaa ccagattgaa tttttaaaca 200

 ctgagttcaa agctacaatg tacaacttgt tggcctacat aaaacaccta 250

 gatggtaaca acgaggcagc cctggaatgc ttacggcaag ctgaagagtt 300

 aatccagcaa gaacatgctg accaagcaga aatcagaagt ctagtcactt 350

 ggggaaacta cgcctgggtc tactatcact tgggcagact ctcagatgct 400

 cagatttatg tagataaggt gaaacaaacc tgcaagaaat tttcaaatcc 450

 atacagtatt gagtattctg aacttgactg tgaggaaggg tggacacaac 500

 tgaagtgtgg aagaaatgaa agggcgaagg tgtgttttga gaaggctctg 550

 gaagaaaagc ccaacaaccc agaattctcc tctggactgg caattgcgat 600

 gtaccatctg gataatcacc cagagaaaca gttctctact gatgttttga 650

 agcaggccat tgagctgagt cctgataacc aatacgtcaa ggttctcttg 700

 ggcctgaaac tgcagaagat gaataaagaa gctgaaggag agcagtttgt 750

 tgaagaagcc ttggaaaagt ctccttgcca aacagatgtc ctccgcagtg 800

 cagccaaatt ttacagaaga aaaggtgacc tagacaaagc tattgaactg 850

 tttcaacggg tgttggaatc cacaccaaac aatggctacc tctatcacca 900

 gattgggtgc tgctacaagg caaaagtaag acaaatgcag aatacaggag 950

 aatctgaagc tagtggaaat aaagagatga ttgaagcact aaagcaatat 1000

 gctatggact attcgaataa agctcttgag aagggactga atcctctgaa 1050

 tgcatactcc gatctcgctg agttcctgga gacggaatgt tatcagacac 1100

 cattcaataa ggaagtccct gatgctgaaa agcaacaaca atcccatcag 1150

 cgctactgca accttcagaa atataatggg aagtctgaag acactgctgt 1200

 gcaacatggt ttagagggtt tgtccataag caaaaaatca actgacaagg 1250

 aagagatcaa agaccaacca cagaatgtat ctgaaaatct gcttccacaa 1300

 aatgcaccaa attattggta tcttcaagga ttaattcata agcagaatgg 1350

 agatctgctg caagccaaat gttatgagaa ggaactgggc cgcctgctaa 1400

 gggatgcccc ttcaggcata ggcagtattt tcctgtcagc atctgagctt 1450

 gaggatggta gtgaggaaat gggccagggc gcagtcagct ccagtcccag 1500

 agagctcctc tctaactcag agcaactgaa ctgagacaga ggaggaaaac 1550

 agagcatcag aagcctgcag tggtggttgt gacgggtagg aggataggaa 1600

 gacagggggc ccaacctggg attgctgagc agggaagctt tgcatgttgc 1650

 tctaaggtac atttttaaag agttgttttt tggccgggcg cagtgctcat 1700

 gcctgtaatc ccagaacttt gggaggccga ggtgggcgga tcacgaggtc 1750

 tggagtttga gaccatcctg gctaacacag tgaaatcccg tctctactaa 1800

 aaatacaaaa aattagccag gcgtggtggc tggcacctgt agtcccagct 1850

 acttgggagg ctgaggcagg agaatggcgt gaacctggaa ggaagaggtt 1900

 gcagagagcc aagattgcg 1919

<210> 1202
<211> 490
<212> PRT
<213> Homo sapien

<400> 1202
 Met Ser Glu Val Thr Lys Asn Ser Leu Glu Lys Ile Leu Pro Gln
   1               5                  10                  15

 Leu Lys Cys His Phe Thr Trp Asn Leu Phe Lys Glu Asp Ser Val
                  20                  25                  30

 Ser Arg Asp Leu Glu Asp Arg Val Cys Asn Gln Ile Glu Phe Leu
                  35                  40                  45

 Asn Thr Glu Phe Lys Ala Thr Met Tyr Asn Leu Leu Ala Tyr Ile
                  50                  55                  60

 Lys His Leu Asp Gly Asn Asn Glu Ala Ala Leu Glu Cys Leu Arg
                  65                  70                  75

 Gln Ala Glu Glu Leu Ile Gln Gln Glu His Ala Asp Gln Ala Glu
                  80                  85                  90

 Ile Arg Ser Leu Val Thr Trp Gly Asn Tyr Ala Trp Val Tyr Tyr
                  95                 100                 105

 His Leu Gly Arg Leu Ser Asp Ala Gln Ile Tyr Val Asp Lys Val
                 110                 115                 120

 Lys Gln Thr Cys Lys Lys Phe Ser Asn Pro Tyr Ser Ile Glu Tyr
                 125                 130                 135

 Ser Glu Leu Asp Cys Glu Glu Gly Trp Thr Gln Leu Lys Cys Gly
                 140                 145                 150

 Arg Asn Glu Arg Ala Lys Val Cys Phe Glu Lys Ala Leu Glu Glu
                 155                 160                 165

 Lys Pro Asn Asn Pro Glu Phe Ser Ser Gly Leu Ala Ile Ala Met
                 170                 175                 180

 Tyr His Leu Asp Asn His Pro Glu Lys Gln Phe Ser Thr Asp Val
                 185                 190                 195

 Leu Lys Gln Ala Ile Glu Leu Ser Pro Asp Asn Gln Tyr Val Lys
                 200                 205                 210

 Val Leu Leu Gly Leu Lys Leu Gln Lys Met Asn Lys Glu Ala Glu
                 215                 220                 225

 Gly Glu Gln Phe Val Glu Glu Ala Leu Glu Lys Ser Pro Cys Gln
                 230                 235                 240

 Thr Asp Val Leu Arg Ser Ala Ala Lys Phe Tyr Arg Arg Lys Gly
                 245                 250                 255

 Asp Leu Asp Lys Ala Ile Glu Leu Phe Gln Arg Val Leu Glu Ser
                 260                 265                 270

 Thr Pro Asn Asn Gly Tyr Leu Tyr His Gln Ile Gly Cys Cys Tyr
                 275                 280                 285

 Lys Ala Lys Val Arg Gln Met Gln Asn Thr Gly Glu Ser Glu Ala
                 290                 295                 300

 Ser Gly Asn Lys Glu Met Ile Glu Ala Leu Lys Gln Tyr Ala Met
                 305                 310                 315

 Asp Tyr Ser Asn Lys Ala Leu Glu Lys Gly Leu Asn Pro Leu Asn
                 320                 325                 330

 Ala Tyr Ser Asp Leu Ala Glu Phe Leu Glu Thr Glu Cys Tyr Gln
                 335                 340                 345

 Thr Pro Phe Asn Lys Glu Val Pro Asp Ala Glu Lys Gln Gln Gln
                 350                 355                 360

 Ser His Gln Arg Tyr Cys Asn Leu Gln Lys Tyr Asn Gly Lys Ser
                 365                 370                 375

 Glu Asp Thr Ala Val Gln His Gly Leu Glu Gly Leu Ser Ile Ser
                 380                 385                 390

 Lys Lys Ser Thr Asp Lys Glu Glu Ile Lys Asp Gln Pro Gln Asn
                 395                 400                 405

 Val Ser Glu Asn Leu Leu Pro Gln Asn Ala Pro Asn Tyr Trp Tyr
                 410                 415                 420

 Leu Gln Gly Leu Ile His Lys Gln Asn Gly Asp Leu Leu Gln Ala
                 425                 430                 435

 Lys Cys Tyr Glu Lys Glu Leu Gly Arg Leu Leu Arg Asp Ala Pro
                 440                 445                 450

 Ser Gly Ile Gly Ser Ile Phe Leu Ser Ala Ser Glu Leu Glu Asp
                 455                 460                 465

 Gly Ser Glu Glu Met Gly Gln Gly Ala Val Ser Ser Ser Pro Arg
                 470                 475                 480

 Glu Leu Leu Ser Asn Ser Glu Gln Leu Asn
                 485                 490

<210> 1203
<211> 4465
<212> DNA
<213> Homo sapien

<400> 1203
 caattgtcat acgacttgca gtgagcgtca ggagcacgtc caggaactcc 50

 tcagcagcgc ctccttcagc tccacagcca gacgccctca gacagcaaag 100

 cctacccccg cgccgcgccc tgcccgccgc tcggatgctc gcccgcgccc 150

 tgctgctgtg cgcggtcctg gcgctcagcc atacagcaaa tccttgctgt 200

 tcccacccat gtcaaaaccg aggtgtatgt atgagtgtgg gatttgacca 250

 gtataagtgc gattgtaccc ggacaggatt ctatggagaa aactgctcaa 300

 caccggaatt tttgacaaga ataaaattat ttctgaaacc cactccaaac 350

 acagtgcact acatacttac ccacttcaag ggattttgga acgttgtgaa 400

 taacattccc ttccttcgaa atgcaattat gagttatgtc ttgacatcca 450

 gatcacattt gattgacagt ccaccaactt acaatgctga ctatggctac 500

 aaaagctggg aagccttctc taacctctcc tattatacta gagcccttcc 550

 tcctgtgcct gatgattgcc cgactccctt gggtgtcaaa ggtaaaaagc 600

 agcttcctga ttcaaatgag attgtggaaa aattgcttct aagaagaaag 650

 ttcatccctg atccccaggg ctcaaacatg atgtttgcat tctttgccca 700

 gcacttcacg catcagtttt tcaagacaga tcataagcga gggccagctt 750

 tcaccaacgg gctgggccat ggggtggact taaatcatat ttacggtgaa 800

 actctggcta gacagcgtaa actgcgcctt ttcaaggatg gaaaaatgaa 850

 atatcagata attgatggag agatgtatcc tcccacagtc aaagatactc 900

 aggcagagat gatctaccct cctcaagtcc ctgagcatct acggtttgct 950

 gtggggcagg aggtctttgg tctggtgcct ggtctgatga tgtatgccac 1000

 aatctggctg cgggaacaca acagagtatg cgatgtgctt aaacaggagc 1050

 atcctgaatg gggtgatgag cagttgttcc agacaagcag gctaatactg 1100

 ataggagaga ctattaagat tgtgattgaa gattatgtgc aacacttgag 1150

 tggctatcac ttcaaactga aatttgaccc agaactactt ttcaacaaac 1200

 aattccagta ccaaaatcgt attgctgctg aatttaacac cctctatcac 1250

 tggcatcccc ttctgcctga cacctttcaa attcatgacc agaaatacaa 1300

 ctatcaacag tttatctaca acaactctat attgctggaa catggaatta 1350

 cccagtttgt tgaatcattc accaggcaaa ttgctggcag ggttgctggt 1400

 ggtaggaatg ttccacccgc agtacagaaa gtatcacagg cttccattga 1450

 ccagagcagg cagatgaaat accagtcttt taatgagtac cgcaaacgct 1500

 ttatgctgaa gccctatgaa tcatttgaag aacttacagg agaaaaggaa 1550

 atgtctgcag agttggaagc actctatggt gacatcgatg ctgtggagct 1600

 gtatcctgcc cttctggtag aaaagcctcg gccagatgcc atctttggtg 1650

 aaaccatggt agaagttgga gcaccattct ccttgaaagg acttatgggt 1700

 aatgttatat gttctcctgc ctactggaag ccaagcactt ttggtggaga 1750

 agtgggtttt caaatcatca acactgcctc aattcagtct ctcatctgca 1800

 ataacgtgaa gggctgtccc tttacttcat tcagtgttcc agatccagag 1850

 ctcattaaaa cagtcaccat caatgcaagt tcttcccgct ccggactaga 1900

 tgatatcaat cccacagtac tactaaaaga acgttcgact gaactgtaga 1950

 agtctaatga tcatatttat ttatttatat gaaccatgtc tattaattta 2000

 attatttaat aatatttata ttaaactcct tatgttactt aacatcttct 2050

 gtaacagaag tcagtactcc tgttgcggag aaaggagtca tacttgtgaa 2100

 gacttttatg tcactactct aaagattttg ctgttgctgt taagtttgga 2150

 aaacagtttt tattctgttt tataaaccag agagaaatga gttttgacgt 2200

 ctttttactt gaatttcaac ttatattata agaacgaaag taaagatgtt 2250

 tgaatactta aacactatca caagatggca aaatgctgaa agtttttaca 2300

 ctgtcgatgt ttccaatgca tcttccatga tgcattagaa gtaactaatg 2350

 tttgaaattt taaagtactt ttggttattt ttctgtcatc aaacaaaaac 2400

 aggtatcagt gcattattaa atgaatattt aaattagaca ttaccagtaa 2450

 tttcatgtct actttttaaa atcagcaatg aaacaataat ttgaaatttc 2500

 taaattcata gggtagaatc acctgtaaaa gcttgtttga tttcttaaag 2550

 ttattaaact tgtacatata ccaaaaagaa gctgtcttgg atttaaatct 2600

 gtaaaatcag atgaaatttt actacaattg cttgttaaaa tattttataa 2650

 gtgatgttcc tttttcacca agagtataaa cctttttagt gtgactgtta 2700

 aaacttcctt ttaaatcaaa atgccaaatt tattaaggtg gtggagccac 2750

 tgcagtgtta tctcaaaata agaatatttt gttgagatat tccagaattt 2800

 gtttatatgg ctggtaacat gtaaaatcta tatcagcaaa agggtctacc 2850

 tttaaaataa gcaataacaa agaagaaaac caaattattg ttcaaattta 2900

 ggtttaaact tttgaagcaa actttttttt atccttgtgc actgcaggcc 2950

 tggtactcag attttgctat gaggttaatg aagtaccaag ctgtgcttga 3000

 ataacgatat gttttctcag attttctgtt gtacagttta atttagcagt 3050

 ccatatcaca ttgcaaaagt agcaatgacc tcataaaata cctcttcaaa 3100

 atgcttaaat tcatttcaca cattaatttt atctcagtct tgaagccaat 3150

 tcagtaggtg cattggaatc aagcctggct acctgcatgc tgttcctttt 3200

 cttttcttct tttagccatt ttgctaagag acacagtctt ctcatcactt 3250

 cgtttctcct attttgtttt actagtttta agatcagagt tcactttctt 3300

 tggactctgc ctatattttc ttacctgaac ttttgcaagt tttcaggtaa 3350

 acctcagctc aggactgcta tttagctcct cttaagaaga ttaaaagaga 3400

 aaaaaaaagg cccttttaaa aatagtatac acttatttta agtgaaaagc 3450

 agagaatttt atttatagct aattttagct atctgtaacc aagatggatg 3500

 caaagaggct agtgcctcag agagaactgt acggggtttg tgactggaaa 3550

 aagttacgtt cccattctaa ttaatgccct ttcttattta aaaacaaaac 3600

 caaatgatat ctaagtagtt ctcagcaata ataataatga cgataatact 3650

 tcttttccac atctcattgt cactgacatt taatggtact gtatattact 3700

 taatttattg aagattatta tttatgtctt attaggacac tatggttata 3750

 aactgtgttt aagcctacaa tcattgattt ttttttgtta tgtcacaatc 3800

 agtatatttt ctttggggtt acctctctga atattatgta aacaatccaa 3850

 agaaatgatt gtattaagat ttgtgaataa atttttagaa atctgattgg 3900

 catattgaga tatttaaggt tgaatgtttg tccttaggat aggcctatgt 3950

 gctagcccac aaagaatatt gtctcattag cctgaatgtg ccataagact 4000

 gaccttttaa aatgttttga gggatctgtg gatgcttcgt taatttgttc 4050

 agccacaatt tattgagaaa atattctgtg tcaagcactg tgggttttaa 4100

 tatttttaaa tcaaacgctg attacagata atagtattta tataaataat 4150

 tgaaaaaaat tttcttttgg gaagagggag aaaatgaaat aaatatcatt 4200

 aaagataact caggagaatc ttctttacaa ttttacgttt agaatgttta 4250

 aggttaagaa agaaatagtc aatatgcttg tataaaacac tgttcactgt 4300

 tttttttaaa aaaaaaactt gatttgttat taacattgat ctgctgacaa 4350

 aacctgggaa tttgggttgt gtatgcgaat gtttcagtgc ctcagacaaa 4400

 tgtgtattta acttatgtaa aagataagtc tggaaataaa tgtctgttta 4450

 tttttgtact attta 4465

<210> 1204
<211> 604
<212> PRT
<213> Homo sapien

<400> 1204
 Met Leu Ala Arg Ala Leu Leu Leu Cys Ala Val Leu Ala Leu Ser
   1               5                  10                  15

 His Thr Ala Asn Pro Cys Cys Ser His Pro Cys Gln Asn Arg Gly
                  20                  25                  30

 Val Cys Met Ser Val Gly Phe Asp Gln Tyr Lys Cys Asp Cys Thr
                  35                  40                  45

 Arg Thr Gly Phe Tyr Gly Glu Asn Cys Ser Thr Pro Glu Phe Leu
                  50                  55                  60

 Thr Arg Ile Lys Leu Phe Leu Lys Pro Thr Pro Asn Thr Val His
                  65                  70                  75

 Tyr Ile Leu Thr His Phe Lys Gly Phe Trp Asn Val Val Asn Asn
                  80                  85                  90

 Ile Pro Phe Leu Arg Asn Ala Ile Met Ser Tyr Val Leu Thr Ser
                  95                 100                 105

 Arg Ser His Leu Ile Asp Ser Pro Pro Thr Tyr Asn Ala Asp Tyr
                 110                 115                 120

 Gly Tyr Lys Ser Trp Glu Ala Phe Ser Asn Leu Ser Tyr Tyr Thr
                 125                 130                 135

 Arg Ala Leu Pro Pro Val Pro Asp Asp Cys Pro Thr Pro Leu Gly
                 140                 145                 150

 Val Lys Gly Lys Lys Gln Leu Pro Asp Ser Asn Glu Ile Val Glu
                 155                 160                 165

 Lys Leu Leu Leu Arg Arg Lys Phe Ile Pro Asp Pro Gln Gly Ser
                 170                 175                 180

 Asn Met Met Phe Ala Phe Phe Ala Gln His Phe Thr His Gln Phe
                 185                 190                 195

 Phe Lys Thr Asp His Lys Arg Gly Pro Ala Phe Thr Asn Gly Leu
                 200                 205                 210

 Gly His Gly Val Asp Leu Asn His Ile Tyr Gly Glu Thr Leu Ala
                 215                 220                 225

 Arg Gln Arg Lys Leu Arg Leu Phe Lys Asp Gly Lys Met Lys Tyr
                 230                 235                 240

 Gln Ile Ile Asp Gly Glu Met Tyr Pro Pro Thr Val Lys Asp Thr
                 245                 250                 255

 Gln Ala Glu Met Ile Tyr Pro Pro Gln Val Pro Glu His Leu Arg
                 260                 265                 270

 Phe Ala Val Gly Gln Glu Val Phe Gly Leu Val Pro Gly Leu Met
                 275                 280                 285

 Met Tyr Ala Thr Ile Trp Leu Arg Glu His Asn Arg Val Cys Asp
                 290                 295                 300

 Val Leu Lys Gln Glu His Pro Glu Trp Gly Asp Glu Gln Leu Phe
                 305                 310                 315

 Gln Thr Ser Arg Leu Ile Leu Ile Gly Glu Thr Ile Lys Ile Val
                 320                 325                 330

 Ile Glu Asp Tyr Val Gln His Leu Ser Gly Tyr His Phe Lys Leu
                 335                 340                 345

 Lys Phe Asp Pro Glu Leu Leu Phe Asn Lys Gln Phe Gln Tyr Gln
                 350                 355                 360

 Asn Arg Ile Ala Ala Glu Phe Asn Thr Leu Tyr His Trp His Pro
                 365                 370                 375

 Leu Leu Pro Asp Thr Phe Gln Ile His Asp Gln Lys Tyr Asn Tyr
                 380                 385                 390

 Gln Gln Phe Ile Tyr Asn Asn Ser Ile Leu Leu Glu His Gly Ile
                 395                 400                 405

 Thr Gln Phe Val Glu Ser Phe Thr Arg Gln Ile Ala Gly Arg Val
                 410                 415                 420

 Ala Gly Gly Arg Asn Val Pro Pro Ala Val Gln Lys Val Ser Gln
                 425                 430                 435

 Ala Ser Ile Asp Gln Ser Arg Gln Met Lys Tyr Gln Ser Phe Asn
                 440                 445                 450

 Glu Tyr Arg Lys Arg Phe Met Leu Lys Pro Tyr Glu Ser Phe Glu
                 455                 460                 465

 Glu Leu Thr Gly Glu Lys Glu Met Ser Ala Glu Leu Glu Ala Leu
                 470                 475                 480

 Tyr Gly Asp Ile Asp Ala Val Glu Leu Tyr Pro Ala Leu Leu Val
                 485                 490                 495

 Glu Lys Pro Arg Pro Asp Ala Ile Phe Gly Glu Thr Met Val Glu
                 500                 505                 510

 Val Gly Ala Pro Phe Ser Leu Lys Gly Leu Met Gly Asn Val Ile
                 515                 520                 525

 Cys Ser Pro Ala Tyr Trp Lys Pro Ser Thr Phe Gly Gly Glu Val
                 530                 535                 540

 Gly Phe Gln Ile Ile Asn Thr Ala Ser Ile Gln Ser Leu Ile Cys
                 545                 550                 555

 Asn Asn Val Lys Gly Cys Pro Phe Thr Ser Phe Ser Val Pro Asp
                 560                 565                 570

 Pro Glu Leu Ile Lys Thr Val Thr Ile Asn Ala Ser Ser Ser Arg
                 575                 580                 585

 Ser Gly Leu Asp Asp Ile Asn Pro Thr Val Leu Leu Lys Glu Arg
                 590                 595                 600

 Ser Thr Glu Leu


<210> 1205
<211> 2634
<212> DNA
<213> Homo sapien

<400> 1205
 attcggctgc ggtacatctc ggcactctag ctgcagccgg gagaggcctt 50

 gccgccaccg ctgtcgccca agcctccact gccgctgcca cctcagcgcc 100

 ggcctctgca tccccagctc cagctccgct ctgcgccgct gctgccatcg 150

 ccgctgccac ctccgcagcc cgggcctccg ccgccgccac tcaagcatcc 200

 gtgagtcatt ttctgcccat ctctggtcgc gcggtctccc tggtagagtt 250

 tgtaggcttg caagatggca gaagcagatt ttaaaatggt ctcggaacct 300

 gtcgcccatg gggttgccga agaggagatg gctagctcga ctagtgattc 350

 tggggaagaa tctgacagca gtagctctag cagcagcact agtgacagca 400

 gcagcagcag cagcactagt ggcagcagca gcggcagcgg cagcagcagc 450

 agcagcagcg gcagcactag cagccgcagc cgcttgtata gaaagaagag 500

 ggtacctgag ccttccagaa gggcgcggcg ggccccgttg ggaacaaatt 550

 tcgtggatag gctgcctcag gcagttagaa atcgtgtgca agcgcttaga 600

 aacattcaag atgaatgtga caaggtagat accctgttct taaaagcaat 650

 tcatgatctt gaaagaaaat atgctgaact caacaagcct ctgtatgata 700

 ggcggtttca aatcatcaat gcagaatacg agcctacaga agaagaatgt 750

 gaatggaatt cagaggatga ggagttcagc agtgatgagg aggtgcagga 800

 taacacccct agtgaaatgc ctcccttaga gggtgaggaa gaagaaaacc 850

 ctaaagaaaa cccagaggtg aaagctgaag agaaggaagt tcctaaagaa 900

 attcctgagg tgaaggatga agaaaaggaa gttcctaaag aaattcctga 950

 ggtaaaggct gaagaaaaag cagattctaa agactgtatg gaggcaaccc 1000

 ctgaagtaaa agaagatcct aaagaagtcc cccaggtaaa ggcagatgat 1050

 aaagaacagc ctaaagcaac agaggctaag gcaagggctg cagtaagaga 1100

 gactcataaa agagttcctg aggaaaggct tcaggacagt gtagatctta 1150

 aaagagctag gaagggaaag cctaaaagag aagaccctaa aggcattcct 1200

 gactattggc tgattgtttt aaagaatgtt gacaagctcg ggcctatgat 1250

 tcagaagtat gatgagccca ttctgaagtt cttgtcggat gttagcctga 1300

 agttctcaaa acctggccag cctgtaagtt acacctttga atttcatttt 1350

 ctacccaacc catacttcag aaatgaggtg ctggtgaaga catatataat 1400

 aaaggcaaaa ccagatcaca atgatccctt cttttcttgg ggatgggaaa 1450

 ttgaagattg caaaggctgc aagatagact ggagaagagg aaaagatgtt 1500

 actgtgacaa ctacccagag tcgcacaact gctactggag aaattgaaat 1550

 ccagccaaga gtggttccta atgcatcatt cttcaacttc tttagtcctc 1600

 ctgagattcc tatgattggg aagctggaac cacgagaaga tgctatcctg 1650

 gatgaggact ttgaaattgg gcagatttta catgataatg tcatcctgaa 1700

 atcaatctat tactatactg gagaagtcaa tggtacctac tatcaatttg 1750

 gcaaacatta tggaaacaag aaatacagaa aataagtcaa tctgaaagat 1800

 ttttcaagaa tcttaaaatc tcaagaagtg aagcagattc atacagcctt 1850

 gaaaaaagta aaaccctgac ctgtaacctg aacactatta ttccttatag 1900

 tcaagttttt gtggtttctt ggtagtctat attttaaaaa tagtcctaaa 1950

 aagtgtctaa gtgccagttt attctatcta ggctgttgta gtataatatt 2000

 cttcaaaata tgtaagctgt tgtcaattat ctaaagcatg ttagtttggt 2050

 gctacacagt gttgattttt gtgatgtcct ttggtcatgt ttctgttaga 2100

 ctgtagctgt gaaactgtca gaattgttaa ctgaaacaaa tatttgcttg 2150

 aaaaaaaaag ttcatgaagt accaatgcaa gtgttttatt tttttctttt 2200

 ttccagccca taagactaag ggtttaaatc tgcttgcact agctgtgcct 2250

 tcattagttt gctatagaaa tccagtactt atagtaaata aaacagtgta 2300

 ttttgaagtt tgactgcttg aaaaagatta gcatacatct aatgtgaaaa 2350

 gaccacattt gattcaactg agaccttgtg tatgtgacat atagtggcct 2400

 ataaatttaa tcataatgat gttattgttt accactgagg tgttaatata 2450

 acatagtatt tttgaaaaag tttcttcatc ttatattgtg taattgtaaa 2500

 ctaaagatac cgtgttttct ttgtattgtg ttctaccttc cctttcactg 2550

 aaaatgatca cttcatttga tactgttttt catgttcttg tattgcaacc 2600

 taaaataaat aaatattaaa gtgtgttata ctat 2634

<210> 1206
<211> 506
<212> PRT
<213> Homo sapien

<400> 1206
 Met Ala Glu Ala Asp Phe Lys Met Val Ser Glu Pro Val Ala His
   1               5                  10                  15

 Gly Val Ala Glu Glu Glu Met Ala Ser Ser Thr Ser Asp Ser Gly
                  20                  25                  30

 Glu Glu Ser Asp Ser Ser Ser Ser Ser Ser Ser Thr Ser Asp Ser
                  35                  40                  45

 Ser Ser Ser Ser Ser Thr Ser Gly Ser Ser Ser Gly Ser Gly Ser
                  50                  55                  60

 Ser Ser Ser Ser Ser Gly Ser Thr Ser Ser Arg Ser Arg Leu Tyr
                  65                  70                  75

 Arg Lys Lys Arg Val Pro Glu Pro Ser Arg Arg Ala Arg Arg Ala
                  80                  85                  90

 Pro Leu Gly Thr Asn Phe Val Asp Arg Leu Pro Gln Ala Val Arg
                  95                 100                 105

 Asn Arg Val Gln Ala Leu Arg Asn Ile Gln Asp Glu Cys Asp Lys
                 110                 115                 120

 Val Asp Thr Leu Phe Leu Lys Ala Ile His Asp Leu Glu Arg Lys
                 125                 130                 135

 Tyr Ala Glu Leu Asn Lys Pro Leu Tyr Asp Arg Arg Phe Gln Ile
                 140                 145                 150

 Ile Asn Ala Glu Tyr Glu Pro Thr Glu Glu Glu Cys Glu Trp Asn
                 155                 160                 165

 Ser Glu Asp Glu Glu Phe Ser Ser Asp Glu Glu Val Gln Asp Asn
                 170                 175                 180

 Thr Pro Ser Glu Met Pro Pro Leu Glu Gly Glu Glu Glu Glu Asn
                 185                 190                 195

 Pro Lys Glu Asn Pro Glu Val Lys Ala Glu Glu Lys Glu Val Pro
                 200                 205                 210

 Lys Glu Ile Pro Glu Val Lys Asp Glu Glu Lys Glu Val Pro Lys
                 215                 220                 225

 Glu Ile Pro Glu Val Lys Ala Glu Glu Lys Ala Asp Ser Lys Asp
                 230                 235                 240

 Cys Met Glu Ala Thr Pro Glu Val Lys Glu Asp Pro Lys Glu Val
                 245                 250                 255

 Pro Gln Val Lys Ala Asp Asp Lys Glu Gln Pro Lys Ala Thr Glu
                 260                 265                 270

 Ala Lys Ala Arg Ala Ala Val Arg Glu Thr His Lys Arg Val Pro
                 275                 280                 285

 Glu Glu Arg Leu Gln Asp Ser Val Asp Leu Lys Arg Ala Arg Lys
                 290                 295                 300

 Gly Lys Pro Lys Arg Glu Asp Pro Lys Gly Ile Pro Asp Tyr Trp
                 305                 310                 315

 Leu Ile Val Leu Lys Asn Val Asp Lys Leu Gly Pro Met Ile Gln
                 320                 325                 330

 Lys Tyr Asp Glu Pro Ile Leu Lys Phe Leu Ser Asp Val Ser Leu
                 335                 340                 345

 Lys Phe Ser Lys Pro Gly Gln Pro Val Ser Tyr Thr Phe Glu Phe
                 350                 355                 360

 His Phe Leu Pro Asn Pro Tyr Phe Arg Asn Glu Val Leu Val Lys
                 365                 370                 375

 Thr Tyr Ile Ile Lys Ala Lys Pro Asp His Asn Asp Pro Phe Phe
                 380                 385                 390

 Ser Trp Gly Trp Glu Ile Glu Asp Cys Lys Gly Cys Lys Ile Asp
                 395                 400                 405

 Trp Arg Arg Gly Lys Asp Val Thr Val Thr Thr Thr Gln Ser Arg
                 410                 415                 420

 Thr Thr Ala Thr Gly Glu Ile Glu Ile Gln Pro Arg Val Val Pro
                 425                 430                 435

 Asn Ala Ser Phe Phe Asn Phe Phe Ser Pro Pro Glu Ile Pro Met
                 440                 445                 450

 Ile Gly Lys Leu Glu Pro Arg Glu Asp Ala Ile Leu Asp Glu Asp
                 455                 460                 465

 Phe Glu Ile Gly Gln Ile Leu His Asp Asn Val Ile Leu Lys Ser
                 470                 475                 480

 Ile Tyr Tyr Tyr Thr Gly Glu Val Asn Gly Thr Tyr Tyr Gln Phe
                 485                 490                 495

 Gly Lys His Tyr Gly Asn Lys Lys Tyr Arg Lys
                 500                 505

<210> 1207
<211> 3865
<212> DNA
<213> Homo sapien

<400> 1207
 tttttcaatt ttgaacattt tgcaaaacga ggggttcgag gcaggtgaga 50

 gcatcctgca cgtcgccggg gagcccgcgg gcacttggcg cgctctcctg 100

 ggaccgtctg cactggaaac ccgaaagttt ttttttaata tatattttta 150

 tgcagatgta tttataaaga tataagtaat ttttttcttc ccttttctcc 200

 accgccttga gagcgagtac ttttggcaaa ggacggagga aaagctcagc 250

 aacattttag ggggcggttg tttctttctt tcttatttct tttttaaggg 300

 gaaaaaattt gagtgcatcg cgatggagaa aatgtcccga ccgctccccc 350

 tgaatcccac ctttatcccg cctccctacg gcgtgctcag gtccctgctg 400

 gagaacccgc tgaagctccc ccttcaccac gaagacgcat ttagtaaaga 450

 taaagacaaa gaaaagaagc tggatgatga gagtaacagc ccgacggtcc 500

 cccagtcggc attcctgggg cctaccttat gggacaaaac ccttccctat 550

 gacggagata ctttccagtt ggaatacatg gacctggagg agtttttgtc 600

 agaaaatggc attcccccca gcccatctca gcatgaccac agccctcacc 650

 ctcctgggct gcagccagct tcctcggctg ccccctcggt catggacctc 700

 agcagccggg cctctgcacc ccttcaccct ggcatcccat ctccgaactg 750

 tatgcagagc cccatcagac caggtcagct gttgccagca aaccgcaata 800

 caccaagtcc cattgatcct gacaccatcc aggtcccagt gggttatgag 850

 ccagacccag cagatcttgc cctttccagc atccctggcc aggaaatgtt 900

 tgaccctcgc aaacgcaagt tctctgagga agaactgaag ccacagccca 950

 tgatcaagaa agctcgcaaa gtcttcatcc ctgatgacct gaaggatgac 1000

 aagtactggg caaggcgcag aaagaacaac atggcagcca agcgctcccg 1050

 cgacgcccgg aggctgaaag agaaccagat cgccatccgg gcctcgttcc 1100

 tggagaagga gaactcggcc ctccgccagg aggtggctga cttgaggaag 1150

 gagctgggca aatgcaagaa catacttgcc aagtatgagg ccaggcacgg 1200

 gcccctgtag gatggcattt ttgcaggctg gctttggaat agatggacag 1250

 tttgtttcct gtctgatagc accacacgca aaccaacctt tctgacatca 1300

 gcactttacc agaggcataa acacaactga ctcccatttt ggtgtgcatc 1350

 tgtgtgtgtg tgcgtgtata tgtgcttgtg ctcatgtgtg tggtcagcgg 1400

 tatgtgcgtg tgcgtgttcc tttgctcttg ccattttaag gtagccctct 1450

 catcgtcttt tagttccaac aaagaaaggt gccatgtctt tactagactg 1500

 aggagccctc tcgcgggtct cccatcccct ccctccttca ctcctgcctc 1550

 ctcagctttg cttcatgttc gagcttacct actcttccag gactctctgc 1600

 ttggattcac taaaaagggc cctggtaaaa tagtggatct cagtttttaa 1650

 gagtacaagc tcttgtttct gtttagtccg taagttacca tgctaatgag 1700

 gtgcacacaa taacttagca ctactccgca gctctagtcc tttataagtt 1750

 gctttcctct tactttcagt tttggtgata atcgtcttca aattaaagtg 1800

 ctgtttagat ttattagatc ccatatttac ttactgctat ctactaagtt 1850

 tccttttaat tctaccaacc ccagataagt aagagtacta ttaatagaac 1900

 acagagtgtg tttttgcact gtctgtacct aaagcaataa tcctattgta 1950

 cgctagagca tgctgcctga gtattactag tggacgtagg atattttccc 2000

 tacctaagaa tttcactgtc ttttaaaaaa caaaaagtaa agtaatgcat 2050

 ttgagcatgg ccagactatt ccctaggaca aggaagcaga gggaaatggg 2100

 aggtctaagg atgaggggtt aatttatcag tacatgagcc aaaaactgcg 2150

 tcttggatta gcctttgaca ttgatgtgtt cggttttgtt gttccccttc 2200

 cctcacaccc tgcctcgccc ccacttttct agttaacttt ttccatatcc 2250

 ctcttgacat tcaaaacagt tacttaagat tcagttttcc cactttttgg 2300

 taatatatat atttttgtga attatacttt gttgttttta aaaagaaaat 2350

 cagttgatta agttaataag ttgatgtttt ctaaggccct ttttcctagt 2400

 ggtgtcattt ttgaatgcct cataaattaa tgattctgaa gcttatgttt 2450

 cttattctct gtttgctttt gaacgtatgt gctcttataa agtggacttc 2500

 tgaaaaatga atgtaaaaga cactggtgta tctcagaagg ggatggtgtt 2550

 gtcacaaact gtggttaatc caatcaattt aaatgtttac tatagaccaa 2600

 aaggagagat tattaaatcg tttaatgttt atacagagta attataggaa 2650

 gttctttttt gtacagtatt tttcagatat aaatactgac aatgtatttt 2700

 ggaagacata tattatatat agaaaagagg agaggaaaac tattccatgt 2750

 tttaaaatta tatagcaaag atatatattc accaatgttg tacagagaag 2800

 aagtgcttgg gggtttttga agtctttaat attttaagcc ctatcactga 2850

 cacatcagca tgttttctgc tttaaattaa aattttatga cagtatcgag 2900

 gcttgtgatg acgaatcctg ctctaaaata cacaaggagc tttcttgttt 2950

 cttattaggc ctcagaaaga agtcagttaa cgtcacccaa aagcacaaaa 3000

 tggattttag tcaaatattt attggatgat acagtgtttt ttaggaaaag 3050

 catctgccac aaaaatgttc acttcgaaat tctgagttcc tggaatggca 3100

 cgttgctgcc agtgccccag acagttcttt tctaccctgc gggcccgcac 3150

 gttttatgag gttgatatcg gtgctatgtg tttggtttat aatttgatag 3200

 atgtttgact ttaaagatga ttgttctttt gtttcattaa gttgtaaaat 3250

 gtcaagaaat tctgctgtta cgacaaagaa acattttacg ctagattaaa 3300

 atatcctttc atcaatggga ttttctagtt tcctgccttc agagtatcta 3350

 atcctttaat gatctggtgg tctcctcgtc aatccatcag caatgcttct 3400

 ctcatagtgt catagacttg ggaaacccaa ccagtaggat atttctacaa 3450

 ggtgttcatt ttgtcacaag ctgtagataa cagcaagaga tgggggtgta 3500

 ttggaattgc aatacattgt tcaggtgaat aataaaatca aaaacttttg 3550

 caatcttaag cagagataaa taaaagatag caatatgaga cacaggtgga 3600

 cgtagagttg gcctttttac aggcaaagag gcgaattgta gaattgttag 3650

 atggcaatag tcattaaaaa catagaaaaa tgatgtcttt aagtggagaa 3700

 ttgtggaagg attgtaacat ggaccatcca aatttatggc cgtatcaaat 3750

 ggtagctgaa aaaactatat ttgagcactg gtctctcttg gaattagatg 3800

 tttatatcaa atgagcatct caaatgtttt ctgcagaaaa aaataaaaag 3850

 attctaataa aaaaa 3865

<210> 1208
<211> 295
<212> PRT
<213> Homo sapien

<400> 1208
 Met Glu Lys Met Ser Arg Pro Leu Pro Leu Asn Pro Thr Phe Ile
   1               5                  10                  15

 Pro Pro Pro Tyr Gly Val Leu Arg Ser Leu Leu Glu Asn Pro Leu
                  20                  25                  30

 Lys Leu Pro Leu His His Glu Asp Ala Phe Ser Lys Asp Lys Asp
                  35                  40                  45

 Lys Glu Lys Lys Leu Asp Asp Glu Ser Asn Ser Pro Thr Val Pro
                  50                  55                  60

 Gln Ser Ala Phe Leu Gly Pro Thr Leu Trp Asp Lys Thr Leu Pro
                  65                  70                  75

 Tyr Asp Gly Asp Thr Phe Gln Leu Glu Tyr Met Asp Leu Glu Glu
                  80                  85                  90

 Phe Leu Ser Glu Asn Gly Ile Pro Pro Ser Pro Ser Gln His Asp
                  95                 100                 105

 His Ser Pro His Pro Pro Gly Leu Gln Pro Ala Ser Ser Ala Ala
                 110                 115                 120

 Pro Ser Val Met Asp Leu Ser Ser Arg Ala Ser Ala Pro Leu His
                 125                 130                 135

 Pro Gly Ile Pro Ser Pro Asn Cys Met Gln Ser Pro Ile Arg Pro
                 140                 145                 150

 Gly Gln Leu Leu Pro Ala Asn Arg Asn Thr Pro Ser Pro Ile Asp
                 155                 160                 165

 Pro Asp Thr Ile Gln Val Pro Val Gly Tyr Glu Pro Asp Pro Ala
                 170                 175                 180

 Asp Leu Ala Leu Ser Ser Ile Pro Gly Gln Glu Met Phe Asp Pro
                 185                 190                 195

 Arg Lys Arg Lys Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro Met
                 200                 205                 210

 Ile Lys Lys Ala Arg Lys Val Phe Ile Pro Asp Asp Leu Lys Asp
                 215                 220                 225

 Asp Lys Tyr Trp Ala Arg Arg Arg Lys Asn Asn Met Ala Ala Lys
                 230                 235                 240

 Arg Ser Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ala Ile
                 245                 250                 255

 Arg Ala Ser Phe Leu Glu Lys Glu Asn Ser Ala Leu Arg Gln Glu
                 260                 265                 270

 Val Ala Asp Leu Arg Lys Glu Leu Gly Lys Cys Lys Asn Ile Leu
                 275                 280                 285

 Ala Lys Tyr Glu Ala Arg His Gly Pro Leu
                 290                 295

<210> 1209
<211> 3030
<212> DNA
<213> Homo sapien

<400> 1209
 ctgcgaggag tcacattaac tttgctctag aagacaactt tacaaggatc 50

 taaaaggaac aggattaaag atgactgaat actgggttcc agaaatttaa 100

 aacaatcagc ttagcaaatc atatattctt ctgtggagct gagaattgat 150

 gtccgctctt ccccgtgatt tggaactttc caatcccaga gaaaagttga 200

 caaagggact gcccaggact gagtccatat ggaagaagaa cttcctcttt 250

 tctctggaga cagtggcaag ccagtacagg ctactctgtc atctttgaag 300

 atgttagatg tgggaaagtg gccaattttt tccctttgtt ctgaagaaga 350

 actacagtta attcgtcagg cttgtgtctt tggcagtgct ggcaatgaag 400

 ttttatacac tacagtaaat gatgagattt ttgtgcttgg cacaaactgc 450

 tgtggctgtt tggggttagg tgacgtccag agcaccattg aacctcggag 500

 actggattct ttaaatggca aaaaaatagc ctgcctcagc tatgggagtg 550

 gtccacatat tgtccttgca acaacagaag gagaagtctt tacctggggt 600

 cataatgctt atagccagct gggcaatggg acaactaatc atggtttagt 650

 gccctgtcat atctctacta atctgtcaaa caaacaagtc attgaagttg 700

 cctgtgggtc ttaccattct ttggtgctaa catctgatgg agaggtattt 750

 gcctggggtt ataataactc tgggcaggta ggatctggat caacagttaa 800

 tcagccaatc cctcgaagag tcactggctg cctacaaaat aaagtagttg 850

 tgaccatagc atgtgggcag atgtgctgca tggcagtagt agacacgggg 900

 gaggtctatg tctggggtta caacggaaac gggcagcttg gactcggcaa 950

 cagtggcaac cagccaaccc cttgcagagt ggcagctttg caaggcatcc 1000

 gtgtccagag ggtcgcctgt ggctacgcac acacattagt attaacagat 1050

 gaaggccaag tgtatgcttg gggcgccaat tcttatgggc agttgggcac 1100

 tggcaataaa agcaaccagt cctatcctac tcctgtcact gtggaaaagg 1150

 acaggattat cgagattgca gcctgtcact ccacacacac gtctgcggcc 1200

 aagacgcagg gtgggcacgt gtacatgtgg ggccagtgcc ggggtcagtc 1250

 cgtgatcctc ccgcacctca cccacttctc ctgcactgac gacgtgtttg 1300

 cctgctttgc cacgcccgcc gtcacgtggc gcctcctctc cgtggaacct 1350

 gatgaccacc tcacagtggc tgagtcactg aagagggaat ttgacaaccc 1400

 ggacactgca gacctgaagt ttctagttga tggaaagtac atttatgcac 1450

 ataaagtcct tctcaagatt cgatgtgagc attttcgttc gtcattggaa 1500

 gataacgagg atgatattgt agaaatgagt gaattttcat atcctgttta 1550

 ccgggccttc ctggaatacc tatacacaga cagcatcagc ctttctcctg 1600

 aggaggcagt aggactgcta gacttggcta cattttatag agaaaatcgt 1650

 ttgaaaaagc tctgccaaca aactatcaag caaggcatct gcgaggagaa 1700

 tgccatcgct ctgctctcgg ctgcggtgaa gtatgatgca caggatttag 1750

 aagaattctg cttcaggttt tgcataaacc atctgactgt agtaacacaa 1800

 acatcaggtt ttgcagaaat ggaccatgat ctcctgaaga actttatcag 1850

 caaagcaagc agagttggag cctttaaaaa ttgatcccat ctgcaggaaa 1900

 gtttttgagc ctttccattt cccctgcaaa agccagagat gaatcacttc 1950

 tctttaatta atagtatgta tgatgagcta tgtttggctg agtacttgta 2000

 actgtcagaa gaaggatggt ggtgagtggt ctttgtctgc ctaaacccag 2050

 agtttatgta gaaagcattg aatgttctga tcagatgtga ctaaggtcaa 2100

 ggaaaaaaaa ttgaaatatc ttatttacca tttcctcttt ttgagtcact 2150

 taaattggac acctttggta ccctggtctc agtatatgct attctggccc 2200

 aaatgttcca ttattcagct ggctgatacc acatagatag cttgacaagg 2250

 agtgctgtct gtccttacca cattttcagc actcagcaca gtgccttgtg 2300

 tataataggc actcaattta ttataaatct tcagtatgtc ctgagaacag 2350

 ctttagtcat ggaatactgg gagaaggaat aactttcaca aaataaactt 2400

 aaaacagcct gtaattattg aggttcacat tcttctggta tatcattctg 2450

 agaaattgtg gctaatttag aacattgttt agaattgaca aaaggccctg 2500

 gcaattaaat tgtcaaggcc caagggctaa ttttaatttt ctttttactt 2550

 ggagtcattc attaatttct cacatgggat tatggagtat gaagtattat 2600

 ctttgaatga aattcctggg ctgatctgcc ttacataatc acataaggtc 2650

 ctttgctttt ctttgtgtta agagggactt gcctctgtaa atgaaaatga 2700

 caatgtgctt ttcttgtagt tgactttcat gtcactcact ataaaatagg 2750

 tctcttaacc tggcaccagt ataactataa agcactagct gagaaggaac 2800

 tgatacttac atttcatgga cagcattaac aagaatgaga taaatttgta 2850

 ctttttagat caaaacaaat tacctaattg caaaagagaa actgaaatgg 2900

 aacatagtct cagattcttc taatgtgtat ctcacaatgt catgtaatgt 2950

 aaaggaaacc cttttggaat tagaattctt gttctgatgc tgaactattt 3000

 ggtaataaag tgcttatttg cagataacag 3030

<210> 1210
<211> 551
<212> PRT
<213> Homo sapien

<400> 1210
 Met Glu Glu Glu Leu Pro Leu Phe Ser Gly Asp Ser Gly Lys Pro
   1               5                  10                  15

 Val Gln Ala Thr Leu Ser Ser Leu Lys Met Leu Asp Val Gly Lys
                  20                  25                  30

 Trp Pro Ile Phe Ser Leu Cys Ser Glu Glu Glu Leu Gln Leu Ile
                  35                  40                  45

 Arg Gln Ala Cys Val Phe Gly Ser Ala Gly Asn Glu Val Leu Tyr
                  50                  55                  60

 Thr Thr Val Asn Asp Glu Ile Phe Val Leu Gly Thr Asn Cys Cys
                  65                  70                  75

 Gly Cys Leu Gly Leu Gly Asp Val Gln Ser Thr Ile Glu Pro Arg
                  80                  85                  90

 Arg Leu Asp Ser Leu Asn Gly Lys Lys Ile Ala Cys Leu Ser Tyr
                  95                 100                 105

 Gly Ser Gly Pro His Ile Val Leu Ala Thr Thr Glu Gly Glu Val
                 110                 115                 120

 Phe Thr Trp Gly His Asn Ala Tyr Ser Gln Leu Gly Asn Gly Thr
                 125                 130                 135

 Thr Asn His Gly Leu Val Pro Cys His Ile Ser Thr Asn Leu Ser
                 140                 145                 150

 Asn Lys Gln Val Ile Glu Val Ala Cys Gly Ser Tyr His Ser Leu
                 155                 160                 165

 Val Leu Thr Ser Asp Gly Glu Val Phe Ala Trp Gly Tyr Asn Asn
                 170                 175                 180

 Ser Gly Gln Val Gly Ser Gly Ser Thr Val Asn Gln Pro Ile Pro
                 185                 190                 195

 Arg Arg Val Thr Gly Cys Leu Gln Asn Lys Val Val Val Thr Ile
                 200                 205                 210

 Ala Cys Gly Gln Met Cys Cys Met Ala Val Val Asp Thr Gly Glu
                 215                 220                 225

 Val Tyr Val Trp Gly Tyr Asn Gly Asn Gly Gln Leu Gly Leu Gly
                 230                 235                 240

 Asn Ser Gly Asn Gln Pro Thr Pro Cys Arg Val Ala Ala Leu Gln
                 245                 250                 255

 Gly Ile Arg Val Gln Arg Val Ala Cys Gly Tyr Ala His Thr Leu
                 260                 265                 270

 Val Leu Thr Asp Glu Gly Gln Val Tyr Ala Trp Gly Ala Asn Ser
                 275                 280                 285

 Tyr Gly Gln Leu Gly Thr Gly Asn Lys Ser Asn Gln Ser Tyr Pro
                 290                 295                 300

 Thr Pro Val Thr Val Glu Lys Asp Arg Ile Ile Glu Ile Ala Ala
                 305                 310                 315

 Cys His Ser Thr His Thr Ser Ala Ala Lys Thr Gln Gly Gly His
                 320                 325                 330

 Val Tyr Met Trp Gly Gln Cys Arg Gly Gln Ser Val Ile Leu Pro
                 335                 340                 345

 His Leu Thr His Phe Ser Cys Thr Asp Asp Val Phe Ala Cys Phe
                 350                 355                 360

 Ala Thr Pro Ala Val Thr Trp Arg Leu Leu Ser Val Glu Pro Asp
                 365                 370                 375

 Asp His Leu Thr Val Ala Glu Ser Leu Lys Arg Glu Phe Asp Asn
                 380                 385                 390

 Pro Asp Thr Ala Asp Leu Lys Phe Leu Val Asp Gly Lys Tyr Ile
                 395                 400                 405

 Tyr Ala His Lys Val Leu Leu Lys Ile Arg Cys Glu His Phe Arg
                 410                 415                 420

 Ser Ser Leu Glu Asp Asn Glu Asp Asp Ile Val Glu Met Ser Glu
                 425                 430                 435

 Phe Ser Tyr Pro Val Tyr Arg Ala Phe Leu Glu Tyr Leu Tyr Thr
                 440                 445                 450

 Asp Ser Ile Ser Leu Ser Pro Glu Glu Ala Val Gly Leu Leu Asp
                 455                 460                 465

 Leu Ala Thr Phe Tyr Arg Glu Asn Arg Leu Lys Lys Leu Cys Gln
                 470                 475                 480

 Gln Thr Ile Lys Gln Gly Ile Cys Glu Glu Asn Ala Ile Ala Leu
                 485                 490                 495

 Leu Ser Ala Ala Val Lys Tyr Asp Ala Gln Asp Leu Glu Glu Phe
                 500                 505                 510

 Cys Phe Arg Phe Cys Ile Asn His Leu Thr Val Val Thr Gln Thr
                 515                 520                 525

 Ser Gly Phe Ala Glu Met Asp His Asp Leu Leu Lys Asn Phe Ile
                 530                 535                 540

 Ser Lys Ala Ser Arg Val Gly Ala Phe Lys Asn
                 545                 550

<210> 1211
<211> 1776
<212> DNA
<213> Homo sapien

<400> 1211
 gggggctgta gctggtgaga ggaagtccta gaggctatgg acactctgct 50

 gctgggatca ccgagatgag cagcagctgc tcagggctga gcagggtcct 100

 ggtggccgtg gctacagccc tggtgtctgc ctcctccccc tgcccccagg 150

 cctggggccc cccaggggtc cagtatgggc agccaggcag gtccgtgaag 200

 ctgtgttgtc ctggagtgac tgccggggac ccagtgtcct ggtttcggga 250

 tggggagcca aagctgctcc agggacctga ctctgggcta gggcatgaac 300

 tggtcctggc ccaggcagac agcactgatg agggcaccta catctgccag 350

 accctggatg gtgcacttgg gggcacagtg accctgcagc tgggctaccc 400

 tccagcccgc cctgttgtct cctgccaagc agccgactat gagaacttct 450

 cttgcacttg gagtcccagc cagatcagcg gtttacccac ccgctacctc 500

 acctcctaca ggaagaagac agtcctagga gctgatagcc agaggaggag 550

 tccatccaca gggccctggc catgcccaca ggatccccta ggggctgccc 600

 gctgtgttgt ccacggggct gagttctgga gccagtaccg gattaatgtg 650

 actgaggtga acccactggg tgccagcaca cgcctgctgg atgtgagctt 700

 gcagagcatc ttgcgccctg acccacccca gggcctgcgg gtagagtcag 750

 taccaggtta cccccgacgc ctgcgagcca gctggacata ccctgcctcc 800

 tggccgtgcc agccccactt cctgctcaag ttccgtttgc agtaccgtcc 850

 ggcgcagcat ccagcctggt ccacggtgga gccagctgga ctggaggagg 900

 tgatcacaga tgctgtggct gggctgcccc atgctgtacg agtcagtgcc 950

 cgggactttc tagatgctgg cacctggagc acctggagcc cggaggcctg 1000

 gggaactccg agcactggga ccataccaaa ggagatacca gcatggggcc 1050

 agctacacac gcagccagag gtggagcctc aggtggacag ccctgctcct 1100

 ccaaggccct ccctccaacc acaccctcgg ctacttgatc acagggactc 1150

 tgtggagcag gtagctgtgc tggcgtcttt gggaatcctt tctttcctgg 1200

 gactggtggc tggggccctg gcactggggc tctggctgag gctgagacgg 1250

 ggtgggaagg atggatcccc aaagcctggg ttcttggcct cagtgattcc 1300

 agtggacagg cgtccaggag ctccaaacct gtagaggacc caggagggct 1350

 tcggcagatt ccacctataa ttctgtcttg ctggtgtgga tagaaaccag 1400

 gcaggacagt agatccctat ggttggatct cagctggaag ttctgtttgg 1450

 agcccatttc tgtgagaccc tgtatttcaa atttgcagct gaaaggtgct 1500

 tgtacctctg atttcacccc agagttggag ttctgctcaa ggaacgtgtg 1550

 taatgtgtac atctgtgtcc atgtgtgacc atgtgtctgt gaggcaggga 1600

 acatgtattc tctgcatgca tgtatgtagg tgcctgggga gtgtgtgtgg 1650

 gtccttggct cttggccttt ccccttgcag gggttgtgca ggtgtgaata 1700

 aagagaataa ggaagttctt ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaa 1776

<210> 1212
<211> 422
<212> PRT
<213> Homo sapien

<400> 1212
 Met Ser Ser Ser Cys Ser Gly Leu Ser Arg Val Leu Val Ala Val
   1               5                  10                  15

 Ala Thr Ala Leu Val Ser Ala Ser Ser Pro Cys Pro Gln Ala Trp
                  20                  25                  30

 Gly Pro Pro Gly Val Gln Tyr Gly Gln Pro Gly Arg Ser Val Lys
                  35                  40                  45

 Leu Cys Cys Pro Gly Val Thr Ala Gly Asp Pro Val Ser Trp Phe
                  50                  55                  60

 Arg Asp Gly Glu Pro Lys Leu Leu Gln Gly Pro Asp Ser Gly Leu
                  65                  70                  75

 Gly His Glu Leu Val Leu Ala Gln Ala Asp Ser Thr Asp Glu Gly
                  80                  85                  90

 Thr Tyr Ile Cys Gln Thr Leu Asp Gly Ala Leu Gly Gly Thr Val
                  95                 100                 105

 Thr Leu Gln Leu Gly Tyr Pro Pro Ala Arg Pro Val Val Ser Cys
                 110                 115                 120

 Gln Ala Ala Asp Tyr Glu Asn Phe Ser Cys Thr Trp Ser Pro Ser
                 125                 130                 135

 Gln Ile Ser Gly Leu Pro Thr Arg Tyr Leu Thr Ser Tyr Arg Lys
                 140                 145                 150

 Lys Thr Val Leu Gly Ala Asp Ser Gln Arg Arg Ser Pro Ser Thr
                 155                 160                 165

 Gly Pro Trp Pro Cys Pro Gln Asp Pro Leu Gly Ala Ala Arg Cys
                 170                 175                 180

 Val Val His Gly Ala Glu Phe Trp Ser Gln Tyr Arg Ile Asn Val
                 185                 190                 195

 Thr Glu Val Asn Pro Leu Gly Ala Ser Thr Arg Leu Leu Asp Val
                 200                 205                 210

 Ser Leu Gln Ser Ile Leu Arg Pro Asp Pro Pro Gln Gly Leu Arg
                 215                 220                 225

 Val Glu Ser Val Pro Gly Tyr Pro Arg Arg Leu Arg Ala Ser Trp
                 230                 235                 240

 Thr Tyr Pro Ala Ser Trp Pro Cys Gln Pro His Phe Leu Leu Lys
                 245                 250                 255

 Phe Arg Leu Gln Tyr Arg Pro Ala Gln His Pro Ala Trp Ser Thr
                 260                 265                 270

 Val Glu Pro Ala Gly Leu Glu Glu Val Ile Thr Asp Ala Val Ala
                 275                 280                 285

 Gly Leu Pro His Ala Val Arg Val Ser Ala Arg Asp Phe Leu Asp
                 290                 295                 300

 Ala Gly Thr Trp Ser Thr Trp Ser Pro Glu Ala Trp Gly Thr Pro
                 305                 310                 315

 Ser Thr Gly Thr Ile Pro Lys Glu Ile Pro Ala Trp Gly Gln Leu
                 320                 325                 330

 His Thr Gln Pro Glu Val Glu Pro Gln Val Asp Ser Pro Ala Pro
                 335                 340                 345

 Pro Arg Pro Ser Leu Gln Pro His Pro Arg Leu Leu Asp His Arg
                 350                 355                 360

 Asp Ser Val Glu Gln Val Ala Val Leu Ala Ser Leu Gly Ile Leu
                 365                 370                 375

 Ser Phe Leu Gly Leu Val Ala Gly Ala Leu Ala Leu Gly Leu Trp
                 380                 385                 390

 Leu Arg Leu Arg Arg Gly Gly Lys Asp Gly Ser Pro Lys Pro Gly
                 395                 400                 405

 Phe Leu Ala Ser Val Ile Pro Val Asp Arg Arg Pro Gly Ala Pro
                 410                 415                 420

 Asn Leu


<210> 1213
<211> 1563
<212> DNA
<213> Homo sapien

<400> 1213
 agttgcagtg gaaagaaatg tgtcatctgt ggtttggttt ttaaaagtgg 50

 aaaactagct gcacatatcc ttttttactg cagatttact ttaaggctca 100

 tattctccaa gtctattctg ctttaaaaag aagacaagaa aagaagtggt 150

 ttatcaaaat cacgttataa tcagattttg accaagcatt ttgtaagatt 200

 gccaagtatg cccacggaca tggaacacac aggacattac ctacatcttg 250

 cctttctgat gacaacagtt ttttctttgt ctcctggaac aaaagcaaac 300

 tatacccgtc tgtgggctaa cagtacttct tcctgggatt cagttattca 350

 aaacaagaca ggcagaaacc aaaatgaaaa cattaacaca aaccctataa 400

 ctcctgaagt agattataaa ggtaattcta caaacatgcc tgaaacatct 450

 cacatcgtag ctttaacttc taaatctgaa caggagcttt atataccttc 500

 tgtcgtcagc aacagtcctt caacagtaca gagcattgaa aacacaagca 550

 aaagtcatgg tgaaattttc aaaaaggatg tctgtgcgga aaacaacaac 600

 aacatggcta tgctaatttg cttaattata attgcagtgc tttttcttat 650

 ctgtaccttt ctatttctat caactgtggt tttggcaaac aaagtctctt 700

 ctctcagacg atcaaaacaa gtaggcaagc gtcagcctag aagcaatggc 750

 gattttctgg caagcggtct atggcccgct gaatcagaca cttggaaaag 800

 aacaaaacag ctcacaggac ccaacctagt gatgcaatct actggagtgc 850

 tcacagctac aagggaaaga aaagatgaag aaggaactga aaaacttact 900

 aacaaacaga taggttagtg aagaaaaatg caaagtagca atgagaaggc 950

 ttatggagta aaaatgaagt cagttggtat ttaatcccaa agtgttgttc 1000

 tgattatcta aaatttgaca tggtagacct tgcaatttag aatcaagcag 1050

 gtgagacagg gagaagtatg cctgcttaat tatttaaact gtgtactttt 1100

 gttttgacac tgaatatttt aaaaagcaaa taataaaata actaagcatt 1150

 tgaggaaaat tttaaggata aattgaggaa actgattaat agagatagca 1200

 agggataatt aaataaatat tccctatgta gcaacagtgg ttagatgatc 1250

 tttgtctgaa tgtaataaaa ctttgaatag ttttagtgtg tccttaaagc 1300

 caagtatatg ctttaacatc aaatggaagt caaattccta atgcatagat 1350

 agagagagct aaactgtgta atttaatggt atcttccttg ctggatgtgg 1400

 cagaatccac accagcttat caaccaacac agctaatttt agaataggtc 1450

 ctttatcttt ccatatggca cacgtaagaa agtgtttttc tactattaat 1500

 attaaattaa aacctttact tttgtataat aaattaaaac tcagaataaa 1550

 cctgtgacca cgt 1563

<210> 1214
<211> 232
<212> PRT
<213> Homo sapien

<400> 1214
 Met Glu His Thr Gly His Tyr Leu His Leu Ala Phe Leu Met Thr
   1               5                  10                  15

 Thr Val Phe Ser Leu Ser Pro Gly Thr Lys Ala Asn Tyr Thr Arg
                  20                  25                  30

 Leu Trp Ala Asn Ser Thr Ser Ser Trp Asp Ser Val Ile Gln Asn
                  35                  40                  45

 Lys Thr Gly Arg Asn Gln Asn Glu Asn Ile Asn Thr Asn Pro Ile
                  50                  55                  60

 Thr Pro Glu Val Asp Tyr Lys Gly Asn Ser Thr Asn Met Pro Glu
                  65                  70                  75

 Thr Ser His Ile Val Ala Leu Thr Ser Lys Ser Glu Gln Glu Leu
                  80                  85                  90

 Tyr Ile Pro Ser Val Val Ser Asn Ser Pro Ser Thr Val Gln Ser
                  95                 100                 105

 Ile Glu Asn Thr Ser Lys Ser His Gly Glu Ile Phe Lys Lys Asp
                 110                 115                 120

 Val Cys Ala Glu Asn Asn Asn Asn Met Ala Met Leu Ile Cys Leu
                 125                 130                 135

 Ile Ile Ile Ala Val Leu Phe Leu Ile Cys Thr Phe Leu Phe Leu
                 140                 145                 150

 Ser Thr Val Val Leu Ala Asn Lys Val Ser Ser Leu Arg Arg Ser
                 155                 160                 165

 Lys Gln Val Gly Lys Arg Gln Pro Arg Ser Asn Gly Asp Phe Leu
                 170                 175                 180

 Ala Ser Gly Leu Trp Pro Ala Glu Ser Asp Thr Trp Lys Arg Thr
                 185                 190                 195

 Lys Gln Leu Thr Gly Pro Asn Leu Val Met Gln Ser Thr Gly Val
                 200                 205                 210

 Leu Thr Ala Thr Arg Glu Arg Lys Asp Glu Glu Gly Thr Glu Lys
                 215                 220                 225

 Leu Thr Asn Lys Gln Ile Gly
                 230

<210> 1215
<211> 1056
<212> DNA
<213> Homo sapien

<400> 1215
 gtctgcgcgg agtctgagcg gcgctcgtcc cgtcccaagg ccgacgccag 50

 cacgccgtca tggcccccgc agcggcgacg gggggcagca ccctgcccag 100

 tggcttctcg gtcttcacca ccttgcccga cttgctcttc atctttgagt 150

 ttatcttcgg gggcctggtg tggatcctgg tggcctcctc cctggtgccc 200

 tggcccctgg tccagggctg ggtgatgttc gtgtctgtgt tctgcttcgt 250

 ggccaccacc accttgatca tcctgtacat aattggagcc cacggtggag 300

 agacttcctg ggtcaccttg gacgcagcct accactgcac cgctgccctc 350

 ttttacctca gcgcctcagt cctggaggcc ctggccacca tcacgatgca 400

 agacggcttc acctacaggc actaccatga aaacattgct gccgtggtgt 450

 tctcctacat agccactctg ctctacgtgg tccatgcggt gttctcttta 500

 atcagatgga agtcttcata aagccgcagt agaacttgag ctgaaaaccc 550

 agatggtgtt aactggccgc cccactttcc ggcataactt tttagaaaac 600

 agaaatgccc ttgatggtgg aaaaaagaaa acaaccaccc ccccactgcc 650

 caaaaaaaaa agccctgccc tgttgctcgt gggtgctgtg tttactctcc 700

 cgtgtgcctt cgcgtccggg ttgggagctt gctgtgtcta acctccaact 750

 gctgtgctgt ctgctagggt cacctcctgt ttgtgaaagg ggaccttctt 800

 gttcgggggt gggaagtggc gaccgtgacc tgagaaggaa agaaagatcc 850

 tctgctgacc cctggagcag ctctcgagaa ctacctgttg gtattgtcca 900

 caagctctcc cgagcgcccc atcttgtgcc atgttttaag tcttcatgga 950

 tgttctgcat gtcatgggga ctaaaactca cccaacagat ctttccagag 1000

 gtccatggtg gaagacgata accctgtgaa atactttata aaatgtctta 1050

 atgttc 1056

<210> 1216
<211> 153
<212> PRT
<213> Homo sapien

<400> 1216
 Met Ala Pro Ala Ala Ala Thr Gly Gly Ser Thr Leu Pro Ser Gly
   1               5                  10                  15

 Phe Ser Val Phe Thr Thr Leu Pro Asp Leu Leu Phe Ile Phe Glu
                  20                  25                  30

 Phe Ile Phe Gly Gly Leu Val Trp Ile Leu Val Ala Ser Ser Leu
                  35                  40                  45

 Val Pro Trp Pro Leu Val Gln Gly Trp Val Met Phe Val Ser Val
                  50                  55                  60

 Phe Cys Phe Val Ala Thr Thr Thr Leu Ile Ile Leu Tyr Ile Ile
                  65                  70                  75

 Gly Ala His Gly Gly Glu Thr Ser Trp Val Thr Leu Asp Ala Ala
                  80                  85                  90

 Tyr His Cys Thr Ala Ala Leu Phe Tyr Leu Ser Ala Ser Val Leu
                  95                 100                 105

 Glu Ala Leu Ala Thr Ile Thr Met Gln Asp Gly Phe Thr Tyr Arg
                 110                 115                 120

 His Tyr His Glu Asn Ile Ala Ala Val Val Phe Ser Tyr Ile Ala
                 125                 130                 135

 Thr Leu Leu Tyr Val Val His Ala Val Phe Ser Leu Ile Arg Trp
                 140                 145                 150

 Lys Ser Ser


<210> 1217
<211> 2755
<212> DNA
<213> Homo sapien

<400> 1217
 cctacccgcg cgcaggccaa gttgctgaat caatggagcc ctccccaacc 50

 cgggcgttcc ccagcgaggc ttccttccca tcctcctgac caccggggct 100

 tttcgtgagc tcgtctctga tctcgcgcaa gagtgacaca caggtgttca 150

 aagacgcttc tggggagtga gggaagcggt ttacgagtga cttggctgga 200

 gcctcagggg cgggcactgg cacggaacac accctgaggc cagccctggc 250

 tgcccaggcg gagctgcctc ttctcccgcg ggttggtgga cccgctcagt 300

 acggagttgg ggaagctctt tcacttcgga ggattgctca acaaccatgc 350

 tgggcatctg gaccctccta cctctggttc ttacgtctgt tgctagatta 400

 tcgtccaaaa gtgttaatgc ccaagtgact gacatcaact ccaagggatt 450

 ggaattgagg aagactgtta ctacagttga gactcagaac ttggaaggcc 500

 tgcatcatga tggccaattc tgccataagc cctgtcctcc aggtgaaagg 550

 aaagctaggg actgcacagt caatggggat gaaccagact gcgtgccctg 600

 ccaagaaggg aaggagtaca cagacaaagc ccatttttct tccaaatgca 650

 gaagatgtag attgtgtgat gaaggacatg gcttagaagt ggaaataaac 700

 tgcacccgga cccagaatac caagtgcaga tgtaaaccaa actttttttg 750

 taactctact gtatgtgaac actgtgaccc ttgcaccaaa tgtgaacatg 800

 gaatcatcaa ggaatgcaca ctcaccagca acaccaagtg caaagaggaa 850

 ggatccagat ctaacttggg gtggctttgt cttcttcttt tgccaattcc 900

 actaattgtt tgggtgaaga gaaaggaagt acagaaaaca tgcagaaagc 950

 acagaaagga aaaccaaggt tctcatgaat ctccaacctt aaatcctgaa 1000

 acagtggcaa taaatttatc tgatgttgac ttgagtaaat atatcaccac 1050

 tattgctgga gtcatgacac taagtcaagt taaaggcttt gttcgaaaga 1100

 atggtgtcaa tgaagccaaa atagatgaga tcaagaatga caatgtccaa 1150

 gacacagcag aacagaaagt tcaactgctt cgtaattggc atcaacttca 1200

 tggaaagaaa gaagcgtatg acacattgat taaagatctc aaaaaagcca 1250

 atctttgtac tcttgcagag aaaattcaga ctatcatcct caaggacatt 1300

 actagtgact cagaaaattc aaacttcaga aatgaaatcc aaagcttggt 1350

 ctagagtgaa aaacaacaaa ttcagttctg agtatatgca attagtgttt 1400

 gaaaagattc ttaatagctg gctgtaaata ctgcttggtt ttttactggg 1450

 tacattttat catttattag cgctgaagag ccaacatatt tgtagatttt 1500

 taatatctca tgattctgcc tccaaggatg tttaaaatct agttgggaaa 1550

 acaaacttca tcaagagtaa atgcagtggc atgctaagta cccaaatagg 1600

 agtgtatgca gaggatgaaa gattaagatt atgctctggc atctaacata 1650

 tgattctgta gtatgaatgt aatcagtgta tgttagtaca aatgtctatc 1700

 cacaggctaa ccccactcta tgaatcaata gaagaagcta tgaccttttg 1750

 ctgaaatatc agttactgaa caggcaggcc actttgcctc taaattacct 1800

 ctgataattc tagagatttt accatatttc taaactttgt ttataactct 1850

 gagaagatca tatttatgta aagtatatgt atttgagtgc agaatttaaa 1900

 taaggctcta cctcaaagac ctttgcacag tttattggtg tcatattata 1950

 caatatttca attgtgaatt cacatagaaa acattaaatt ataatgtttg 2000

 actattatat atgtgtatgc attttactgg ctcaaaacta cctacttctt 2050

 tctcaggcat caaaagcatt ttgagcagga gagtattact agagctttgc 2100

 cacctctcca tttttgcctt ggtgctcatc ttaatggcct aatgcacccc 2150

 caaacatgga aatatcacca aaaaatactt aatagtccac caaaaggcaa 2200

 gactgccctt agaaattcta gcctggtttg gagatactaa ctgctctcag 2250

 agaaagtagc tttgtgacat gtcatgaacc catgtttgca atcaaagatg 2300

 ataaaataga ttcttatttt tcccccaccc ccgaaaatgt tcaataatgt 2350

 cccatgtaaa acctgctaca aatggcagct tatacatagc aatggtaaaa 2400

 tcatcatctg gatttaggaa ttgctcttgt cataccccca agtttctaag 2450

 atttaagatt ctccttacta ctatcctacg tttaaatatc tttgaaagtt 2500

 tgtattaaat gtgaatttta agaaataata tttatatttc tgtaaatgta 2550

 aactgtgaag atagttataa actgaagcag atacctggaa ccacctaaag 2600

 aacttccatt tatggaggat ttttttgccc cttgtgtttg gaattataaa 2650

 atataggtaa aagtacgtaa ttaaataatg tttttggtaa aaaaaaaaaa 2700

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2750

 aaaaa 2755

<210> 1218
<211> 335
<212> PRT
<213> Homo sapien

<400> 1218
 Met Leu Gly Ile Trp Thr Leu Leu Pro Leu Val Leu Thr Ser Val
   1               5                  10                  15

 Ala Arg Leu Ser Ser Lys Ser Val Asn Ala Gln Val Thr Asp Ile
                  20                  25                  30

 Asn Ser Lys Gly Leu Glu Leu Arg Lys Thr Val Thr Thr Val Glu
                  35                  40                  45

 Thr Gln Asn Leu Glu Gly Leu His His Asp Gly Gln Phe Cys His
                  50                  55                  60

 Lys Pro Cys Pro Pro Gly Glu Arg Lys Ala Arg Asp Cys Thr Val
                  65                  70                  75

 Asn Gly Asp Glu Pro Asp Cys Val Pro Cys Gln Glu Gly Lys Glu
                  80                  85                  90

 Tyr Thr Asp Lys Ala His Phe Ser Ser Lys Cys Arg Arg Cys Arg
                  95                 100                 105

 Leu Cys Asp Glu Gly His Gly Leu Glu Val Glu Ile Asn Cys Thr
                 110                 115                 120

 Arg Thr Gln Asn Thr Lys Cys Arg Cys Lys Pro Asn Phe Phe Cys
                 125                 130                 135

 Asn Ser Thr Val Cys Glu His Cys Asp Pro Cys Thr Lys Cys Glu
                 140                 145                 150

 His Gly Ile Ile Lys Glu Cys Thr Leu Thr Ser Asn Thr Lys Cys
                 155                 160                 165

 Lys Glu Glu Gly Ser Arg Ser Asn Leu Gly Trp Leu Cys Leu Leu
                 170                 175                 180

 Leu Leu Pro Ile Pro Leu Ile Val Trp Val Lys Arg Lys Glu Val
                 185                 190                 195

 Gln Lys Thr Cys Arg Lys His Arg Lys Glu Asn Gln Gly Ser His
                 200                 205                 210

 Glu Ser Pro Thr Leu Asn Pro Glu Thr Val Ala Ile Asn Leu Ser
                 215                 220                 225

 Asp Val Asp Leu Ser Lys Tyr Ile Thr Thr Ile Ala Gly Val Met
                 230                 235                 240

 Thr Leu Ser Gln Val Lys Gly Phe Val Arg Lys Asn Gly Val Asn
                 245                 250                 255

 Glu Ala Lys Ile Asp Glu Ile Lys Asn Asp Asn Val Gln Asp Thr
                 260                 265                 270

 Ala Glu Gln Lys Val Gln Leu Leu Arg Asn Trp His Gln Leu His
                 275                 280                 285

 Gly Lys Lys Glu Ala Tyr Asp Thr Leu Ile Lys Asp Leu Lys Lys
                 290                 295                 300

 Ala Asn Leu Cys Thr Leu Ala Glu Lys Ile Gln Thr Ile Ile Leu
                 305                 310                 315

 Lys Asp Ile Thr Ser Asp Ser Glu Asn Ser Asn Phe Arg Asn Glu
                 320                 325                 330

 Ile Gln Ser Leu Val
                 335

<210> 1219
<211> 2508
<212> DNA
<213> Homo sapien

<400> 1219
 cctacccgcg cgcaggccaa gttgctgaat caatggagcc ctccccaacc 50

 cgggcgttcc ccagcgaggc ttccttccca tcctcctgac caccggggct 100

 tttcgtgagc tcgtctctga tctcgcgcaa gagtgacaca caggtgttca 150

 aagacgcttc tggggagtga gggaagcggt ttacgagtga cttggctgga 200

 gcctcagggg cgggcactgg cacggaacac accctgaggc cagccctggc 250

 tgcccaggcg gagctgcctc ttctcccgcg ggttggtgga cccgctcagt 300

 acggagttgg ggaagctctt tcacttcgga ggattgctca acaaccatgc 350

 tgggcatctg gaccctccta cctctggttc ttacgtctgt tgctagatta 400

 tcgtccaaaa gtgttaatgc ccaagtgact gacatcaact ccaagggatt 450

 ggaattgagg aagactgtta ctacagttga gactcagaac ttggaaggcc 500

 tgcatcatga tggccaattc tgccataagc cctgtcctcc agatgtgaac 550

 atggaatcat caaggaatgc acactcacca gcaacaccaa gtgcaaagag 600

 gaaggatcca gatctaactt ggggtggctt tgtcttcttc ttttgccaat 650

 tccactaatt gtttgggtga agagaaagga agtacagaaa acatgcagaa 700

 agcacagaaa ggaaaaccaa ggttctcatg aatctccaac cttaaatcct 750

 gaaacagtgg caataaattt atctgatgtt gacttgagta aatatatcac 800

 cactattgct ggagtcatga cactaagtca agttaaaggc tttgttcgaa 850

 agaatggtgt caatgaagcc aaaatagatg agatcaagaa tgacaatgtc 900

 caagacacag cagaacagaa agttcaactg cttcgtaatt ggcatcaact 950

 tcatggaaag aaagaagcgt atgacacatt gattaaagat ctcaaaaaag 1000

 ccaatctttg tactcttgca gagaaaattc agactatcat cctcaaggac 1050

 attactagtg actcagaaaa ttcaaacttc agaaatgaaa tccaaagctt 1100

 ggtctagagt gaaaaacaac aaattcagtt ctgagtatat gcaattagtg 1150

 tttgaaaaga ttcttaatag ctggctgtaa atactgcttg gttttttact 1200

 gggtacattt tatcatttat tagcgctgaa gagccaacat atttgtagat 1250

 ttttaatatc tcatgattct gcctccaagg atgtttaaaa tctagttggg 1300

 aaaacaaact tcatcaagag taaatgcagt ggcatgctaa gtacccaaat 1350

 aggagtgtat gcagaggatg aaagattaag attatgctct ggcatctaac 1400

 atatgattct gtagtatgaa tgtaatcagt gtatgttagt acaaatgtct 1450

 atccacaggc taaccccact ctatgaatca atagaagaag ctatgacctt 1500

 ttgctgaaat atcagttact gaacaggcag gccactttgc ctctaaatta 1550

 cctctgataa ttctagagat tttaccatat ttctaaactt tgtttataac 1600

 tctgagaaga tcatatttat gtaaagtata tgtatttgag tgcagaattt 1650

 aaataaggct ctacctcaaa gacctttgca cagtttattg gtgtcatatt 1700

 atacaatatt tcaattgtga attcacatag aaaacattaa attataatgt 1750

 ttgactatta tatatgtgta tgcattttac tggctcaaaa ctacctactt 1800

 ctttctcagg catcaaaagc attttgagca ggagagtatt actagagctt 1850

 tgccacctct ccatttttgc cttggtgctc atcttaatgg cctaatgcac 1900

 ccccaaacat ggaaatatca ccaaaaaata cttaatagtc caccaaaagg 1950

 caagactgcc cttagaaatt ctagcctggt ttggagatac taactgctct 2000

 cagagaaagt agctttgtga catgtcatga acccatgttt gcaatcaaag 2050

 atgataaaat agattcttat ttttccccca cccccgaaaa tgttcaataa 2100

 tgtcccatgt aaaacctgct acaaatggca gcttatacat agcaatggta 2150

 aaatcatcat ctggatttag gaattgctct tgtcataccc ccaagtttct 2200

 aagatttaag attctcctta ctactatcct acgtttaaat atctttgaaa 2250

 gtttgtatta aatgtgaatt ttaagaaata atatttatat ttctgtaaat 2300

 gtaaactgtg aagatagtta taaactgaag cagatacctg gaaccaccta 2350

 aagaacttcc atttatggag gatttttttg ccccttgtgt ttggaattat 2400

 aaaatatagg taaaagtacg taattaaata atgtttttgg taaaaaaaaa 2450

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2500

 aaaaaaaa 2508

<210> 1220
<211> 103
<212> PRT
<213> Homo sapien

<400> 1220
 Met Leu Gly Ile Trp Thr Leu Leu Pro Leu Val Leu Thr Ser Val
   1               5                  10                  15

 Ala Arg Leu Ser Ser Lys Ser Val Asn Ala Gln Val Thr Asp Ile
                  20                  25                  30

 Asn Ser Lys Gly Leu Glu Leu Arg Lys Thr Val Thr Thr Val Glu
                  35                  40                  45

 Thr Gln Asn Leu Glu Gly Leu His His Asp Gly Gln Phe Cys His
                  50                  55                  60

 Lys Pro Cys Pro Pro Asp Val Asn Met Glu Ser Ser Arg Asn Ala
                  65                  70                  75

 His Ser Pro Ala Thr Pro Ser Ala Lys Arg Lys Asp Pro Asp Leu
                  80                  85                  90

 Thr Trp Gly Gly Phe Val Phe Phe Phe Cys Gln Phe His
                  95                 100

<210> 1221
<211> 3129
<212> DNA
<213> Homo sapien

<400> 1221
 cccgcactaa agacgcttct tcccggcggg taggaatccc gccggcgagc 50

 cgaacagttc cccgagcgca gcccgcggac caccacccgg ccgcacgggc 100

 cgcttttgtc ccccgcccgc cgcttctgtc cgagaggccg cccgcgaggc 150

 gcatcctgac cgcgagcgtc gggtcccaga gccgggcgcg gctggggccc 200

 gaggctagca tctctcggga gccgcaaggc gagagctgca aagtttaatt 250

 agacacttca gaattttgat cacctaatgt tgatttcaga tgtaaaagtc 300

 aagagaagac tctaaaaata gcaaagatgc ttttgagcca gaatgccttc 350

 atcttcagat cacttaattt ggttctcatg gtgtatatca gcctcgtgtt 400

 tggtatttca tatgattcgc ctgattacac agatgaatct tgcactttca 450

 agatatcatt gcgaaatttc cggtccatct tatcatggga attaaaaaac 500

 cactccattg taccaactca ctatacattg ctgtatacaa tcatgagtaa 550

 accagaagat ttgaaggtgg ttaagaactg tgcaaatacc acaagatcat 600

 tttgtgacct cacagatgag tggagaagca cacacgaggc ctatgtcacc 650

 gtcctagaag gattcagcgg gaacacaacg ttgttcagtt gctcacacaa 700

 tttctggctg gccatagaca tgtcttttga accaccagag tttgagattg 750

 ttggttttac caaccacatt aatgtgatgg tgaaatttcc atctattgtt 800

 gaggaagaat tacagtttga tttatctctc gtcattgaag aacagtcaga 850

 gggaattgtt aagaagcata aacccgaaat aaaaggaaac atgagtggaa 900

 atttcaccta tatcattgac aagttaattc caaacacgaa ctactgtgta 950

 tctgtttatt tagagcacag tgatgagcaa gcagtaataa agtctccctt 1000

 aaaatgcacc ctccttccac ctggccagga atcagaatca gcagaatctg 1050

 ccaaaatagg aggaataatt actgtgtttt tgatagcatt ggtcttgaca 1100

 agcaccatag tgacactgaa atggattggt tatatatgct taagaaatag 1150

 cctccccaaa gtcttgaggc aaggtctcgc taagggctgg aatgcagtgg 1200

 ctattcacag gtgcagtcat aatgcactac agtctgaaac tcctgagctc 1250

 aaacagtcgt cctgcctaag cttccccagt agctgggatt acaagcgtgc 1300

 atccctgtgc cccagtgatt aagttttatt atgtagaaaa taaagagcaa 1350

 acagtacagc tgatatggac tctctctctc tttttttttt tttttaagaa 1400

 ttttcataac tttttagcct ggccatttcc taacctgcca ccgttggaag 1450

 ccatggatat ggtggaggtc atttacatca acagaaagaa gaaagtgtgg 1500

 gattataatt atgatgatga aagtgatagc gatactgagg cagcgcccag 1550

 gacaagtggc ggtggctata ccatgcatgg actgactgtc aggcctctgg 1600

 gtcaggcctc tgccacctct acagaatccc agttgataga cccggagtcc 1650

 gaggaggagc ctgacctgcc tgaggttgat gtggagctcc ccacgatgcc 1700

 aaaggacagc cctcagcagt tggaactctt gagtgggccc tgtgagagga 1750

 gaaagagtcc actccaggac ccttttcccg aagaggacta cagctccacg 1800

 gaggggtctg ggggcagaat taccttcaat gtggacttaa actctgtgtt 1850

 tttgagagtt cttgatgacg aggacagtga cgacttagaa gcccctctga 1900

 tgctatcgtc tcatctggaa gagatggttg acccagagga tcctgataat 1950

 gtgcaatcaa accatttgct ggccagcggg gaagggacac agccaacctt 2000

 tcccagcccc tcttcagagg gcctgtggtc cgaagatgct ccatctgatc 2050

 aaagtgacac ttctgagtca gatgttgacc ttggggatgg ttatataatg 2100

 agatgactcc aaaactattg aatgaacttg gacagacaag cacctacagg 2150

 gttctttgtc tctgcatcct aacttgctgc cttatcgtct gcaagtgttc 2200

 tccaagggaa ggaggaggaa actgtggtgt tcctttcttc caggtgacat 2250

 cacctatgca cattcccagt atggggacca tagtatcatt cagtgcattg 2300

 tttacatatt caaagtggtg cactttgaag gaagcacatg tgcacctttc 2350

 ctttacacta atgcacttag gatgtttctg catcatgtct accagggagc 2400

 agggttcccc acagtttcag aggtggtcca ggaccctatg atatttctct 2450

 tctttcgttc tttttttttt ttttttgaga cagagtctcg ttctgtcgcc 2500

 caagctggag cgcaatggtg tgatcttggc tcactgcaac atccgcctcc 2550

 cgggttcagg tgattctcct gcctcagcct ccctcgcaag tagctgggat 2600

 tacaggcgcc tgccaccatg cctagcaaat ttttgtattt ttagtggaga 2650

 caggatttta ccatgttggc caggctggtc tcgaactcct gacctcaagt 2700

 gatctgccct cctcagcctc gtaaagtgct gggattacag gggtgagccg 2750

 ctgtgcctgg ctggccctgt gatatttctg tgaaataaat tgggccaggg 2800

 tgggagcagg gaaagaaaag gaaaatagta gcaagagctg caaagcaggc 2850

 aggaagggag gaggagagcc aggtgagcag tggagagaag gggggccctg 2900

 cacaaggaaa cagggaagag ccatcgaagt ttcagtcggt gagccttggg 2950

 cacctcaccc atgtcacatc ctgtctcctg caattggaat tccaccttgt 3000

 ccagccctcc ccagttaaag tggggaagac agactttagg atcacgtgtg 3050

 tgactaatac agaaaggaaa catggcgtcg gggagaggga taaaacctga 3100

 atgccatatt ttaagttaaa aaaaaaaaa 3129

<210> 1222
<211> 331
<212> PRT
<213> Homo sapien

<400> 1222
 Met Leu Leu Ser Gln Asn Ala Phe Ile Phe Arg Ser Leu Asn Leu
   1               5                  10                  15

 Val Leu Met Val Tyr Ile Ser Leu Val Phe Gly Ile Ser Tyr Asp
                  20                  25                  30

 Ser Pro Asp Tyr Thr Asp Glu Ser Cys Thr Phe Lys Ile Ser Leu
                  35                  40                  45

 Arg Asn Phe Arg Ser Ile Leu Ser Trp Glu Leu Lys Asn His Ser
                  50                  55                  60

 Ile Val Pro Thr His Tyr Thr Leu Leu Tyr Thr Ile Met Ser Lys
                  65                  70                  75

 Pro Glu Asp Leu Lys Val Val Lys Asn Cys Ala Asn Thr Thr Arg
                  80                  85                  90

 Ser Phe Cys Asp Leu Thr Asp Glu Trp Arg Ser Thr His Glu Ala
                  95                 100                 105

 Tyr Val Thr Val Leu Glu Gly Phe Ser Gly Asn Thr Thr Leu Phe
                 110                 115                 120

 Ser Cys Ser His Asn Phe Trp Leu Ala Ile Asp Met Ser Phe Glu
                 125                 130                 135

 Pro Pro Glu Phe Glu Ile Val Gly Phe Thr Asn His Ile Asn Val
                 140                 145                 150

 Met Val Lys Phe Pro Ser Ile Val Glu Glu Glu Leu Gln Phe Asp
                 155                 160                 165

 Leu Ser Leu Val Ile Glu Glu Gln Ser Glu Gly Ile Val Lys Lys
                 170                 175                 180

 His Lys Pro Glu Ile Lys Gly Asn Met Ser Gly Asn Phe Thr Tyr
                 185                 190                 195

 Ile Ile Asp Lys Leu Ile Pro Asn Thr Asn Tyr Cys Val Ser Val
                 200                 205                 210

 Tyr Leu Glu His Ser Asp Glu Gln Ala Val Ile Lys Ser Pro Leu
                 215                 220                 225

 Lys Cys Thr Leu Leu Pro Pro Gly Gln Glu Ser Glu Ser Ala Glu
                 230                 235                 240

 Ser Ala Lys Ile Gly Gly Ile Ile Thr Val Phe Leu Ile Ala Leu
                 245                 250                 255

 Val Leu Thr Ser Thr Ile Val Thr Leu Lys Trp Ile Gly Tyr Ile
                 260                 265                 270

 Cys Leu Arg Asn Ser Leu Pro Lys Val Leu Arg Gln Gly Leu Ala
                 275                 280                 285

 Lys Gly Trp Asn Ala Val Ala Ile His Arg Cys Ser His Asn Ala
                 290                 295                 300

 Leu Gln Ser Glu Thr Pro Glu Leu Lys Gln Ser Ser Cys Leu Ser
                 305                 310                 315

 Phe Pro Ser Ser Trp Asp Tyr Lys Arg Ala Ser Leu Cys Pro Ser
                 320                 325                 330

 Asp


<210> 1223
<211> 1702
<212> DNA
<213> Homo sapien

<400> 1223
 ggagtcgacc gctcgggcag cgcaccgcca cgagagcccg ggacgcggga 50

 aagaccgaaa ggaagaggaa gaggcaccgg tggccatggg gctggaggcg 100

 gcgcgcgagc tggagtgcgc ggcgctgggc acgctgctgc gggatccgcg 150

 ggaggcggaa cgcacgctgc tgctggactg ccgccccttc ctggccttct 200

 gccggcgcca cgtgcgcgcc gcgcggccag tgccttggaa cgcgctgctg 250

 cggcgccgcg cgcgcggccc tcctgccgcc gttctcgcct gcctgctgcc 300

 cgaccgcgcg ctgcggacgc gcctggtccg cggggagctg gcgcgggccg 350

 tggtgctgga cgagggcagt gcctcggtgg cggagctccg gcccgacagc 400

 ccggctcatg tgctgctggc cgcgctgctg cacgagaccc gcgcggggcc 450

 cactgccgtg tacttcctgc gaggaggctt cgacggcttc cagggctgct 500

 gtcccgatct gtgctctgag gcccccgccc ctgcgctgcc gccaacaggg 550

 gacaaaacca gccgctccga ctccagggct cctgtctacg accagggtgg 600

 ccctgtggag atcttgccct acctgttcct gggcagctgc agtcactcgt 650

 cagacctgca ggggctgcag gcctgtggca tcacagccgt cctcaacgtg 700

 tccgccagct gccccaacca ctttgagggc cttttccgct acaagagtat 750

 ccctgtggag gacaaccaga tggtggagat cagtgcctgg ttccaggagg 800

 ccataggctt cattgactgg gtgaagaaca gcggaggccg ggtgctggtg 850

 cactgccagg cgggtatctc gcgctctgcc accatctgtc tggcatacct 900

 catgcagagt cgccgtgtgc ggctggacga ggcctttgac ttcgttaagc 950

 agcgccgggg ggtcatctcc cccaacttca gtttcatggg gcagctgctg 1000

 cagtttgaga cccaggtgct gtgtcactga ggtggtgccc ctctgcctgc 1050

 ctgccccact gtgctggcag gagctgactg tggactggtg ggctcccctc 1100

 tgggccagca cagtcccctc acctccggca gggctgctac ctcctcagag 1150

 tttcagaagc ccccacatgg gggctctagg aatgccggca tgctggtctt 1200

 tccgacctgg tgctcttctg ctgggggact gaggctggcc ctcattcggg 1250

 gtcgggaacc aagggtgtgt ctgctctttc cctccccatc ctctggcaga 1300

 aatcagctag acgctatacc gtggactctc cctggtccac caccatgttg 1350

 aagcccttgg cagcctgaga gctccaagga acaagctgtg acaaccagga 1400

 gccctgtctg tgggttcgtc tgcccagggc ctggagccca agccctgtgt 1450

 tcctggggaa gctggggact tgggaagtga tgggtgtgtc atgttgcgtg 1500

 tgtctgtctg tgagcctttc acacctgtgc tggcgctgga aaattatttg 1550

 tgctcagctg acatttaaca cttcctcccc cgcttcctcc tagccctgtg 1600

 ggcaggggtt ggaaacttag cactttatat ttatacagaa cattcaggat 1650

 ttgtcaataa aatattgtta tatttaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aa 1702

<210> 1224
<211> 314
<212> PRT
<213> Homo sapien

<400> 1224
 Met Gly Leu Glu Ala Ala Arg Glu Leu Glu Cys Ala Ala Leu Gly
   1               5                  10                  15

 Thr Leu Leu Arg Asp Pro Arg Glu Ala Glu Arg Thr Leu Leu Leu
                  20                  25                  30

 Asp Cys Arg Pro Phe Leu Ala Phe Cys Arg Arg His Val Arg Ala
                  35                  40                  45

 Ala Arg Pro Val Pro Trp Asn Ala Leu Leu Arg Arg Arg Ala Arg
                  50                  55                  60

 Gly Pro Pro Ala Ala Val Leu Ala Cys Leu Leu Pro Asp Arg Ala
                  65                  70                  75

 Leu Arg Thr Arg Leu Val Arg Gly Glu Leu Ala Arg Ala Val Val
                  80                  85                  90

 Leu Asp Glu Gly Ser Ala Ser Val Ala Glu Leu Arg Pro Asp Ser
                  95                 100                 105

 Pro Ala His Val Leu Leu Ala Ala Leu Leu His Glu Thr Arg Ala
                 110                 115                 120

 Gly Pro Thr Ala Val Tyr Phe Leu Arg Gly Gly Phe Asp Gly Phe
                 125                 130                 135

 Gln Gly Cys Cys Pro Asp Leu Cys Ser Glu Ala Pro Ala Pro Ala
                 140                 145                 150

 Leu Pro Pro Thr Gly Asp Lys Thr Ser Arg Ser Asp Ser Arg Ala
                 155                 160                 165

 Pro Val Tyr Asp Gln Gly Gly Pro Val Glu Ile Leu Pro Tyr Leu
                 170                 175                 180

 Phe Leu Gly Ser Cys Ser His Ser Ser Asp Leu Gln Gly Leu Gln
                 185                 190                 195

 Ala Cys Gly Ile Thr Ala Val Leu Asn Val Ser Ala Ser Cys Pro
                 200                 205                 210

 Asn His Phe Glu Gly Leu Phe Arg Tyr Lys Ser Ile Pro Val Glu
                 215                 220                 225

 Asp Asn Gln Met Val Glu Ile Ser Ala Trp Phe Gln Glu Ala Ile
                 230                 235                 240

 Gly Phe Ile Asp Trp Val Lys Asn Ser Gly Gly Arg Val Leu Val
                 245                 250                 255

 His Cys Gln Ala Gly Ile Ser Arg Ser Ala Thr Ile Cys Leu Ala
                 260                 265                 270

 Tyr Leu Met Gln Ser Arg Arg Val Arg Leu Asp Glu Ala Phe Asp
                 275                 280                 285

 Phe Val Lys Gln Arg Arg Gly Val Ile Ser Pro Asn Phe Ser Phe
                 290                 295                 300

 Met Gly Gln Leu Leu Gln Phe Glu Thr Gln Val Leu Cys His
                 305                 310

<210> 1225
<211> 6662
<212> DNA
<213> Homo sapien

<400> 1225
 ggcggttaag tcctgtacct aggaaagagg gcgagctctg gggcgctctc 50

 cggtgtcatg aggagcttca aaagagtcaa ctttgggact ctgctaagca 100

 gccagaagga ggctgaagag ttgctgcccg acttgaaggt gggggtgctg 150

 cctggctcgg gatacacctg gctttccaaa ctgagctgtt ttgtgtttgc 200

 cttttgaaga gatggataag agttcctgtc caaccctcca gctggttttc 250

 ccagcagccg atctgatgct gagaggagac aagcttgtga tgccatcctg 300

 agggcttgca accagcagct gactgctaag ctagcttgcc ctaggcatct 350

 ggggagcctg ctggagctgg cagagctggc ctgtgatggc tacttagtgt 400

 ctaccccaca gcgtcctccc ctctacctgg aacgaattct ctttgtctta 450

 ctgcggaatg ctgctgcaca aggaagccca gaggccacac tccgccttgc 500

 tcagcccctc catgcctgct tggtgcagtg ctctcgcgag gctgctcccc 550

 aggactatga ggccgtggct cggggcagct tttctctgct ttggaagggg 600

 gcagaagccc tgttggaacg gcgagctgca tttgcagctc ggctgaaggc 650

 cttgagcttc ctagtactct tggaggatga aagtacccct tgtgaggttc 700

 ctcactttgc ttctccaaca gcctgtcgag cggtagctgc ccatcagcta 750

 tttgatgcca gtggccatgg tctaaatgaa gcagatgctg atttcctaga 800

 tgacctgctc tccaggcacg tgatcagagc cttggtgggt gagagaggga 850

 gctcttctgg gcttctttct ccccagaggg ccctctgcct cttggagctc 900

 accttggaac actgccgtcg cttttgctgg agccgccacc atgacaaagc 950

 catcagcgca gtggagaagg ctcacagtta cctaaggaac accaatctag 1000

 cccctagcct tcagctatgt cagctggggg ttaagctgct gcaggtcggg 1050

 gaggaaggac ctcaggcagt ggccaagctt ctgatcaagg catcagctgt 1100

 cctgagcaag agtatggagg caccatcacc cccacttcgg gcattgtatg 1150

 agagctgcca gttcttcctt tcaggcctgg aacgaggcac caagaggcgc 1200

 tatagacttg atgccattct gagcctcttt gcttttcttg gagggtactg 1250

 ctctcttctg cagcagctgc gggatgatgg tgtgtatggg ggctcctcca 1300

 agcaacagca gtcttttctt cagatgtact ttcagggact tcacctctac 1350

 actgtggtgg tttatgactt tgcccaaggc tgtcagatag ttgatttggc 1400

 tgacctgacc caactagtgg acagttgtaa atctaccgtt gtctggatgc 1450

 tggaggcctt agagggcctg tcgggccaag agctgacgga ccacatgggg 1500

 atgaccgctt cttacaccag taatttggcc tacagcttct atagtcacaa 1550

 gctctatgcc gaggcctgtg ccatctctga gccgctctgt cagcacctgg 1600

 gtttggtgaa gccaggcact tatcccgagg tgcctcctga gaagttgcac 1650

 aggtgcttcc ggctacaagt agagagtttg aagaaactgg gtaaacaggc 1700

 ccagggctgc aagatggtga ttttgtggct ggcagccctg caaccctgta 1750

 gccctgaaca catggctgag ccagtcactt tctgggttcg ggtcaagatg 1800

 gatgcggcca gggctggaga caaggagcta cagctaaaga ctctgcgaga 1850

 cagcctcagt ggctgggacc cggagaccct ggccctcctg ctgagggagg 1900

 agctgcaggc ctacaaggcg gtgcgggccg acactggaca ggaacgcttc 1950

 aacatcatct gtgacctcct ggagctgagc cccgaggaga caccagccgg 2000

 ggcctgggca cgagccaccc acctggtaga actggctcag gtgctctgct 2050

 accacgactt tacgcagcag accaactgct ctgctctgga tgctatccgg 2100

 gaagccctgc agcttctgga ctctgtgagg cctgaggccc aggccagaga 2150

 tcagcttctg gacgataaag cacaggcctt gctgtggctt tacatctgta 2200

 ctctggaagc caaaatacag gaaggtatcg agcgggatcg gagagcccag 2250

 gcccctggta acttggagga atttgaagtc aatgacctga actatgaaga 2300

 taaactccag gaagatcgtt tcctatacag taacattgcc ttcaacctgg 2350

 ctgcagatgc tgctcagtcc aaatgcctgg accaagccct ggccctgtgg 2400

 aaggagctgc ttacaaaggg gcaggcccca gctgtacggt gtctccagca 2450

 gacagcagcc tcactgcaga tcctagcagc cctctaccag ctggtggcaa 2500

 agcccatgca ggctctggag gtcctcctgc tgctacggat tgtctctgag 2550

 agactgaagg accactcgaa ggcagctggc tcctcctgcc acatcaccca 2600

 gctcctcctg accctcggct gtcccagcta tgcccagtta cacctggaag 2650

 aggcagcatc gagcctgaag catctcgatc agactactga cacatacctg 2700

 ctcctttccc tgacctgtga tctgcttcga agtcaactct actggactca 2750

 ccagaaggtg accaagggtg tctctctgct gctgtctgtg cttcgggatc 2800

 ctgccctcca gaagtcctcc aaggcttggt acttgctgcg tgtccaggtc 2850

 ctgcagctgg tggcagctta ccttagcctc ccgtcaaaca acctctcaca 2900

 ctccctgtgg gagcagctct gtgcccaagg ctggcagaca cctgagatag 2950

 ctctcataga ctcccataag ctcctccgaa gcatcatcct cctgctgatg 3000

 ggcagtgaca ttctctcaac tcagaaagca gctgtggaga catcgttttt 3050

 ggactatggt gaaaatctgg tacaaaaatg gcaggttctt tcagaggtgc 3100

 tgagctgctc agagaagctg gtctgccacc tgggccgcct gggtagtgtg 3150

 agtgaagcca aggccttttg cttggaggcc ctaaaactta caacaaagct 3200

 gcagatacca cgccagtgtg ccctgttcct ggtgctgaag ggcgagctgg 3250

 agctggcccg caatgacatt gatctctgtc agtcggacct gcagcaggtt 3300

 ctgttcttgc ttgagtcttg cacagagttt ggtggggtga ctcagcacct 3350

 ggactctgtg aagaaggtcc acctgcagaa ggggaagcag caggcccagg 3400

 tcccctgtcc tccacagctc ccagaggagg agctcttcct aagaggccct 3450

 gctctagagc tggtggccac tgtggccaag gagcctggcc ccatagcacc 3500

 ttctacaaac tcctccccag tcttgaaaac caagccccag cccataccca 3550

 acttcctgtc ccattcaccc acctgtgact gctcgctctg cgccagccct 3600

 gtcctcacag cagtctgtct gcgctgggta ttggtcacgg caggggtgag 3650

 gctggccatg ggccaccaag cccagggtct ggatctgctg caggtcgtgc 3700

 tgaagggctg tcctgaagcc gctgagcgcc tcacccaagc tctccaagct 3750

 tccctgaatc ataaaacacc cccctccttg gttccaagcc tcttggatga 3800

 gatcttggct caagcataca cactgttggc actggagggc ctgaaccagc 3850

 catcaaacga gagcctgcag aaggttctac agtcagggct gaagtttgta 3900

 gcagcacgga taccccacct agagccctgg cgagccagcc tgctcttgat 3950

 ttgggccctc acaaaactag gtggcctcag ctgctgtact acccaacttt 4000

 ttgcaagctc ctggggctgg cagccaccat taataaaaag tgtccctggc 4050

 tcagagccct ctaagactca gggccaaaaa cgttctggac gagggcgcca 4100

 aaagttagcc tctgctcccc tgagcctcaa taatacctct cagaaaggtc 4150

 tggaaggtag aggactgccc tgcacaccta aacccccaga ccggatcagg 4200

 caagctggcc ctcatgtccc cttcacggtg tttgaggaag tctgccctac 4250

 agagagcaag cctgaagtac cccaggcccc cagggtacaa cagagagtcc 4300

 agacgcgcct caaggtgaac ttcagtgatg acagtgactt ggaagaccct 4350

 gtctcagctg aggcctggct ggcagaggag cctaagagac ggggcactgc 4400

 ttcccggggc cgggggcgag caaggaaggg cctgagccta aagacggatg 4450

 ccgtggttgc cccaggtagt gcccctggga accctggcct gaatggcagg 4500

 agccggaggg ccaagaaggt ggcatcaaga cattgtgagg agcggcgtcc 4550

 ccagagggcc agtgaccagg ccaggcctgg ccctgagatc atgaggacca 4600

 tccctgagga agaactgact gacaactgga gaaaaatgag ctttgagatc 4650

 ctcaggggct ctgacgggga agactcagcc tcaggtggga agactccagc 4700

 tccgggccct gaggcagctt ctggagaatg ggagctgctg aggctggatt 4750

 ccagcaagaa gaagctgccc agcccatgcc cagacaagga gagtgacaag 4800

 gaccttggtc ctcggctcca gctcccctca gcccccgtag ccactggtct 4850

 ttctaccctg gactccatct gtgactccct gagtgttgct ttccggggca 4900

 ttagtcactg tcctcctagt gggctctatg cccacctctg ccgcttcctg 4950

 gccttgtgcc tgggccaccg ggatccttat gccactgctt tccttgtcac 5000

 cgagtctgtc tccatcacct gtcgccacca gctgctcacc cacctccaca 5050

 gacagctcag caaggcccag aagcaccgag gatcacttga aatagcagac 5100

 cagctgcagg ggctgagcct tcaggagatg cctggagatg tccccctggc 5150

 ccgcatccag cgcctctttt ccttcagggc tttggaatct ggccacttcc 5200

 cccagcctga aaaggagagt ttccaggagc gcctggctct gatccccagt 5250

 ggggtgactg tgtgtgtgtt ggccctggcc accctccagc ccggaaccgt 5300

 gggcaacacc ctcctgctga cccggctgga aaaggacagt cccccagtca 5350

 gtgtgcagat tcccactggc cagaacaagc ttcatctgcg ttcagtcctg 5400

 aatgagtttg atgccatcca gaaggcacag aaagagaaca gcagctgtac 5450

 tgacaagcga gaatggtgga cagggcggct ggcactggac cacaggatgg 5500

 aggttctcat cgcttcccta gagaagtctg tgctgggctg ctggaagggg 5550

 ctgctgctgc cgtccagtga ggagcccggc cctgcccagg aggcctcccg 5600

 cctacaggag ctgctacagg actgtggctg gaaatatcct gaccgcactc 5650

 tgctgaaaat catgctcagt ggtgccggtg ccctcacccc tcaggacatt 5700

 caggccctgg cctacgggct gtgcccaacc cagccagagc gagcccagga 5750

 gctcctgaat gaggcagtag gacgtctaca gggcctgaca gtaccaagca 5800

 atagccacct tgtcttggtc ctagacaagg acttgcagaa gctgccgtgg 5850

 gaaagcatgc ccagcctcca agcactgcct gtcacccggc tgccctcctt 5900

 ccgcttccta ctcagctact ccatcatcaa agagtatggg gcctcgccag 5950

 tgctgagtca aggggtggat ccacgaagta ccttctatgt cctgaaccct 6000

 cacaataacc tgtcaagcac agaggagcaa tttcgagcca atttcagcag 6050

 tgaagctggc tggagaggag tggttgggga ggtgccaaga cctgaacagg 6100

 tgcaggaagc cctgacaaag catgatttgt atatctatgc agggcatggg 6150

 gctggtgccc gcttccttga tgggcaggct gtcctgcggc tgagctgtcg 6200

 ggcagtggcc ctgctgtttg gctgtagcag tgcggccctg gctgtgcatg 6250

 gaaacctgga gggggctggc atcgtgctca agtacatcat ggctggttgc 6300

 cccttgtttc tgggtaatct ctgggatgtg actgaccgcg acattgaccg 6350

 ctacacggaa gctctgctgc aaggctggct tggagcaggc ccaggggccc 6400

 cccttctcta ctatgtaaac caggcccgcc aagctccccg actcaagtat 6450

 cttattgggg ctgcacctat agcctatggc ttgcctgtct ctctgcggta 6500

 accccatgga gctgtcttat tgatgctaga agcctcataa ctgttctacc 6550

 tccaaggtta gatttaatcc ttaggataac tcttttaaag tgattttccc 6600

 cagtgtttta tatgaaacat ttccttttga tttaacctca gtataataaa 6650

 gatacatcat tt 6662

<210> 1226
<211> 1795
<212> PRT
<213> Homo sapien

<400> 1226
 Met Glu Ala Pro Ser Pro Pro Leu Arg Ala Leu Tyr Glu Ser Cys
   1               5                  10                  15

 Gln Phe Phe Leu Ser Gly Leu Glu Arg Gly Thr Lys Arg Arg Tyr
                  20                  25                  30

 Arg Leu Asp Ala Ile Leu Ser Leu Phe Ala Phe Leu Gly Gly Tyr
                  35                  40                  45

 Cys Ser Leu Leu Gln Gln Leu Arg Asp Asp Gly Val Tyr Gly Gly
                  50                  55                  60

 Ser Ser Lys Gln Gln Gln Ser Phe Leu Gln Met Tyr Phe Gln Gly
                  65                  70                  75

 Leu His Leu Tyr Thr Val Val Val Tyr Asp Phe Ala Gln Gly Cys
                  80                  85                  90

 Gln Ile Val Asp Leu Ala Asp Leu Thr Gln Leu Val Asp Ser Cys
                  95                 100                 105

 Lys Ser Thr Val Val Trp Met Leu Glu Ala Leu Glu Gly Leu Ser
                 110                 115                 120

 Gly Gln Glu Leu Thr Asp His Met Gly Met Thr Ala Ser Tyr Thr
                 125                 130                 135

 Ser Asn Leu Ala Tyr Ser Phe Tyr Ser His Lys Leu Tyr Ala Glu
                 140                 145                 150

 Ala Cys Ala Ile Ser Glu Pro Leu Cys Gln His Leu Gly Leu Val
                 155                 160                 165

 Lys Pro Gly Thr Tyr Pro Glu Val Pro Pro Glu Lys Leu His Arg
                 170                 175                 180

 Cys Phe Arg Leu Gln Val Glu Ser Leu Lys Lys Leu Gly Lys Gln
                 185                 190                 195

 Ala Gln Gly Cys Lys Met Val Ile Leu Trp Leu Ala Ala Leu Gln
                 200                 205                 210

 Pro Cys Ser Pro Glu His Met Ala Glu Pro Val Thr Phe Trp Val
                 215                 220                 225

 Arg Val Lys Met Asp Ala Ala Arg Ala Gly Asp Lys Glu Leu Gln
                 230                 235                 240

 Leu Lys Thr Leu Arg Asp Ser Leu Ser Gly Trp Asp Pro Glu Thr
                 245                 250                 255

 Leu Ala Leu Leu Leu Arg Glu Glu Leu Gln Ala Tyr Lys Ala Val
                 260                 265                 270

 Arg Ala Asp Thr Gly Gln Glu Arg Phe Asn Ile Ile Cys Asp Leu
                 275                 280                 285

 Leu Glu Leu Ser Pro Glu Glu Thr Pro Ala Gly Ala Trp Ala Arg
                 290                 295                 300

 Ala Thr His Leu Val Glu Leu Ala Gln Val Leu Cys Tyr His Asp
                 305                 310                 315

 Phe Thr Gln Gln Thr Asn Cys Ser Ala Leu Asp Ala Ile Arg Glu
                 320                 325                 330

 Ala Leu Gln Leu Leu Asp Ser Val Arg Pro Glu Ala Gln Ala Arg
                 335                 340                 345

 Asp Gln Leu Leu Asp Asp Lys Ala Gln Ala Leu Leu Trp Leu Tyr
                 350                 355                 360

 Ile Cys Thr Leu Glu Ala Lys Ile Gln Glu Gly Ile Glu Arg Asp
                 365                 370                 375

 Arg Arg Ala Gln Ala Pro Gly Asn Leu Glu Glu Phe Glu Val Asn
                 380                 385                 390

 Asp Leu Asn Tyr Glu Asp Lys Leu Gln Glu Asp Arg Phe Leu Tyr
                 395                 400                 405

 Ser Asn Ile Ala Phe Asn Leu Ala Ala Asp Ala Ala Gln Ser Lys
                 410                 415                 420

 Cys Leu Asp Gln Ala Leu Ala Leu Trp Lys Glu Leu Leu Thr Lys
                 425                 430                 435

 Gly Gln Ala Pro Ala Val Arg Cys Leu Gln Gln Thr Ala Ala Ser
                 440                 445                 450

 Leu Gln Ile Leu Ala Ala Leu Tyr Gln Leu Val Ala Lys Pro Met
                 455                 460                 465

 Gln Ala Leu Glu Val Leu Leu Leu Leu Arg Ile Val Ser Glu Arg
                 470                 475                 480

 Leu Lys Asp His Ser Lys Ala Ala Gly Ser Ser Cys His Ile Thr
                 485                 490                 495

 Gln Leu Leu Leu Thr Leu Gly Cys Pro Ser Tyr Ala Gln Leu His
                 500                 505                 510

 Leu Glu Glu Ala Ala Ser Ser Leu Lys His Leu Asp Gln Thr Thr
                 515                 520                 525

 Asp Thr Tyr Leu Leu Leu Ser Leu Thr Cys Asp Leu Leu Arg Ser
                 530                 535                 540

 Gln Leu Tyr Trp Thr His Gln Lys Val Thr Lys Gly Val Ser Leu
                 545                 550                 555

 Leu Leu Ser Val Leu Arg Asp Pro Ala Leu Gln Lys Ser Ser Lys
                 560                 565                 570

 Ala Trp Tyr Leu Leu Arg Val Gln Val Leu Gln Leu Val Ala Ala
                 575                 580                 585

 Tyr Leu Ser Leu Pro Ser Asn Asn Leu Ser His Ser Leu Trp Glu
                 590                 595                 600

 Gln Leu Cys Ala Gln Gly Trp Gln Thr Pro Glu Ile Ala Leu Ile
                 605                 610                 615

 Asp Ser His Lys Leu Leu Arg Ser Ile Ile Leu Leu Leu Met Gly
                 620                 625                 630

 Ser Asp Ile Leu Ser Thr Gln Lys Ala Ala Val Glu Thr Ser Phe
                 635                 640                 645

 Leu Asp Tyr Gly Glu Asn Leu Val Gln Lys Trp Gln Val Leu Ser
                 650                 655                 660

 Glu Val Leu Ser Cys Ser Glu Lys Leu Val Cys His Leu Gly Arg
                 665                 670                 675

 Leu Gly Ser Val Ser Glu Ala Lys Ala Phe Cys Leu Glu Ala Leu
                 680                 685                 690

 Lys Leu Thr Thr Lys Leu Gln Ile Pro Arg Gln Cys Ala Leu Phe
                 695                 700                 705

 Leu Val Leu Lys Gly Glu Leu Glu Leu Ala Arg Asn Asp Ile Asp
                 710                 715                 720

 Leu Cys Gln Ser Asp Leu Gln Gln Val Leu Phe Leu Leu Glu Ser
                 725                 730                 735

 Cys Thr Glu Phe Gly Gly Val Thr Gln His Leu Asp Ser Val Lys
                 740                 745                 750

 Lys Val His Leu Gln Lys Gly Lys Gln Gln Ala Gln Val Pro Cys
                 755                 760                 765

 Pro Pro Gln Leu Pro Glu Glu Glu Leu Phe Leu Arg Gly Pro Ala
                 770                 775                 780

 Leu Glu Leu Val Ala Thr Val Ala Lys Glu Pro Gly Pro Ile Ala
                 785                 790                 795

 Pro Ser Thr Asn Ser Ser Pro Val Leu Lys Thr Lys Pro Gln Pro
                 800                 805                 810

 Ile Pro Asn Phe Leu Ser His Ser Pro Thr Cys Asp Cys Ser Leu
                 815                 820                 825

 Cys Ala Ser Pro Val Leu Thr Ala Val Cys Leu Arg Trp Val Leu
                 830                 835                 840

 Val Thr Ala Gly Val Arg Leu Ala Met Gly His Gln Ala Gln Gly
                 845                 850                 855

 Leu Asp Leu Leu Gln Val Val Leu Lys Gly Cys Pro Glu Ala Ala
                 860                 865                 870

 Glu Arg Leu Thr Gln Ala Leu Gln Ala Ser Leu Asn His Lys Thr
                 875                 880                 885

 Pro Pro Ser Leu Val Pro Ser Leu Leu Asp Glu Ile Leu Ala Gln
                 890                 895                 900

 Ala Tyr Thr Leu Leu Ala Leu Glu Gly Leu Asn Gln Pro Ser Asn
                 905                 910                 915

 Glu Ser Leu Gln Lys Val Leu Gln Ser Gly Leu Lys Phe Val Ala
                 920                 925                 930

 Ala Arg Ile Pro His Leu Glu Pro Trp Arg Ala Ser Leu Leu Leu
                 935                 940                 945

 Ile Trp Ala Leu Thr Lys Leu Gly Gly Leu Ser Cys Cys Thr Thr
                 950                 955                 960

 Gln Leu Phe Ala Ser Ser Trp Gly Trp Gln Pro Pro Leu Ile Lys
                 965                 970                 975

 Ser Val Pro Gly Ser Glu Pro Ser Lys Thr Gln Gly Gln Lys Arg
                 980                 985                 990

 Ser Gly Arg Gly Arg Gln Lys Leu Ala Ser Ala Pro Leu Ser Leu
                 995                1000                1005

 Asn Asn Thr Ser Gln Lys Gly Leu Glu Gly Arg Gly Leu Pro Cys
                1010                1015                1020

 Thr Pro Lys Pro Pro Asp Arg Ile Arg Gln Ala Gly Pro His Val
                1025                1030                1035

 Pro Phe Thr Val Phe Glu Glu Val Cys Pro Thr Glu Ser Lys Pro
                1040                1045                1050

 Glu Val Pro Gln Ala Pro Arg Val Gln Gln Arg Val Gln Thr Arg
                1055                1060                1065

 Leu Lys Val Asn Phe Ser Asp Asp Ser Asp Leu Glu Asp Pro Val
                1070                1075                1080

 Ser Ala Glu Ala Trp Leu Ala Glu Glu Pro Lys Arg Arg Gly Thr
                1085                1090                1095

 Ala Ser Arg Gly Arg Gly Arg Ala Arg Lys Gly Leu Ser Leu Lys
                1100                1105                1110

 Thr Asp Ala Val Val Ala Pro Gly Ser Ala Pro Gly Asn Pro Gly
                1115                1120                1125

 Leu Asn Gly Arg Ser Arg Arg Ala Lys Lys Val Ala Ser Arg His
                1130                1135                1140

 Cys Glu Glu Arg Arg Pro Gln Arg Ala Ser Asp Gln Ala Arg Pro
                1145                1150                1155

 Gly Pro Glu Ile Met Arg Thr Ile Pro Glu Glu Glu Leu Thr Asp
                1160                1165                1170

 Asn Trp Arg Lys Met Ser Phe Glu Ile Leu Arg Gly Ser Asp Gly
                1175                1180                1185

 Glu Asp Ser Ala Ser Gly Gly Lys Thr Pro Ala Pro Gly Pro Glu
                1190                1195                1200

 Ala Ala Ser Gly Glu Trp Glu Leu Leu Arg Leu Asp Ser Ser Lys
                1205                1210                1215

 Lys Lys Leu Pro Ser Pro Cys Pro Asp Lys Glu Ser Asp Lys Asp
                1220                1225                1230

 Leu Gly Pro Arg Leu Gln Leu Pro Ser Ala Pro Val Ala Thr Gly
                1235                1240                1245

 Leu Ser Thr Leu Asp Ser Ile Cys Asp Ser Leu Ser Val Ala Phe
                1250                1255                1260

 Arg Gly Ile Ser His Cys Pro Pro Ser Gly Leu Tyr Ala His Leu
                1265                1270                1275

 Cys Arg Phe Leu Ala Leu Cys Leu Gly His Arg Asp Pro Tyr Ala
                1280                1285                1290

 Thr Ala Phe Leu Val Thr Glu Ser Val Ser Ile Thr Cys Arg His
                1295                1300                1305

 Gln Leu Leu Thr His Leu His Arg Gln Leu Ser Lys Ala Gln Lys
                1310                1315                1320

 His Arg Gly Ser Leu Glu Ile Ala Asp Gln Leu Gln Gly Leu Ser
                1325                1330                1335

 Leu Gln Glu Met Pro Gly Asp Val Pro Leu Ala Arg Ile Gln Arg
                1340                1345                1350

 Leu Phe Ser Phe Arg Ala Leu Glu Ser Gly His Phe Pro Gln Pro
                1355                1360                1365

 Glu Lys Glu Ser Phe Gln Glu Arg Leu Ala Leu Ile Pro Ser Gly
                1370                1375                1380

 Val Thr Val Cys Val Leu Ala Leu Ala Thr Leu Gln Pro Gly Thr
                1385                1390                1395

 Val Gly Asn Thr Leu Leu Leu Thr Arg Leu Glu Lys Asp Ser Pro
                1400                1405                1410

 Pro Val Ser Val Gln Ile Pro Thr Gly Gln Asn Lys Leu His Leu
                1415                1420                1425

 Arg Ser Val Leu Asn Glu Phe Asp Ala Ile Gln Lys Ala Gln Lys
                1430                1435                1440

 Glu Asn Ser Ser Cys Thr Asp Lys Arg Glu Trp Trp Thr Gly Arg
                1445                1450                1455

 Leu Ala Leu Asp His Arg Met Glu Val Leu Ile Ala Ser Leu Glu
                1460                1465                1470

 Lys Ser Val Leu Gly Cys Trp Lys Gly Leu Leu Leu Pro Ser Ser
                1475                1480                1485

 Glu Glu Pro Gly Pro Ala Gln Glu Ala Ser Arg Leu Gln Glu Leu
                1490                1495                1500

 Leu Gln Asp Cys Gly Trp Lys Tyr Pro Asp Arg Thr Leu Leu Lys
                1505                1510                1515

 Ile Met Leu Ser Gly Ala Gly Ala Leu Thr Pro Gln Asp Ile Gln
                1520                1525                1530

 Ala Leu Ala Tyr Gly Leu Cys Pro Thr Gln Pro Glu Arg Ala Gln
                1535                1540                1545

 Glu Leu Leu Asn Glu Ala Val Gly Arg Leu Gln Gly Leu Thr Val
                1550                1555                1560

 Pro Ser Asn Ser His Leu Val Leu Val Leu Asp Lys Asp Leu Gln
                1565                1570                1575

 Lys Leu Pro Trp Glu Ser Met Pro Ser Leu Gln Ala Leu Pro Val
                1580                1585                1590

 Thr Arg Leu Pro Ser Phe Arg Phe Leu Leu Ser Tyr Ser Ile Ile
                1595                1600                1605

 Lys Glu Tyr Gly Ala Ser Pro Val Leu Ser Gln Gly Val Asp Pro
                1610                1615                1620

 Arg Ser Thr Phe Tyr Val Leu Asn Pro His Asn Asn Leu Ser Ser
                1625                1630                1635

 Thr Glu Glu Gln Phe Arg Ala Asn Phe Ser Ser Glu Ala Gly Trp
                1640                1645                1650

 Arg Gly Val Val Gly Glu Val Pro Arg Pro Glu Gln Val Gln Glu
                1655                1660                1665

 Ala Leu Thr Lys His Asp Leu Tyr Ile Tyr Ala Gly His Gly Ala
                1670                1675                1680

 Gly Ala Arg Phe Leu Asp Gly Gln Ala Val Leu Arg Leu Ser Cys
                1685                1690                1695

 Arg Ala Val Ala Leu Leu Phe Gly Cys Ser Ser Ala Ala Leu Ala
                1700                1705                1710

 Val His Gly Asn Leu Glu Gly Ala Gly Ile Val Leu Lys Tyr Ile
                1715                1720                1725

 Met Ala Gly Cys Pro Leu Phe Leu Gly Asn Leu Trp Asp Val Thr
                1730                1735                1740

 Asp Arg Asp Ile Asp Arg Tyr Thr Glu Ala Leu Leu Gln Gly Trp
                1745                1750                1755

 Leu Gly Ala Gly Pro Gly Ala Pro Leu Leu Tyr Tyr Val Asn Gln
                1760                1765                1770

 Ala Arg Gln Ala Pro Arg Leu Lys Tyr Leu Ile Gly Ala Ala Pro
                1775                1780                1785

 Ile Ala Tyr Gly Leu Pro Val Ser Leu Arg
                1790                1795

<210> 1227
<211> 2937
<212> DNA
<213> Homo sapien

<400> 1227
 acgcgtccgc ttcggaatga gagactcaac cataatagaa agaatggaga 50

 actattaacc accattcttc agtgggctgt gattttcaga ggggaatact 100

 aagaaatggt tttccatact ggaacccaaa ggtaaagaca ctcaaggaca 150

 gacatttttg gcagagcata gatgaaaatg gcaagttccc tggctttcct 200

 tctgctcaac tttcatgtct ccctcttctt ggtccagctg ctcactcctt 250

 gctcagctca gttttctgtg cttggaccct ctgggcccat cctggccatg 300

 gtgggtgaag acgctgatct gccctgtcac ctgttcccga ccatgagtgc 350

 agagaccatg gagctgaggt gggtgagttc cagcctaagg caggtggtga 400

 acgtgtatgc agatggaaag gaagtggaag acaggcagag tgcaccatat 450

 cgagggagaa cttcgattct gcgggatggc atcactgcag ggaaggctgc 500

 tctccgaata cacaacgtca cagcctctga cagtggaaag tacttgtgtt 550

 atttccaaga tggtgacttc tacgaaaaag ccctggtgga gctgaaggtt 600

 gcagcattgg gttctgatct tcacattgaa gtgaagggtt atgaggatgg 650

 agggatccat ctggagtgca ggtccactgg ctggtacccc caaccccaaa 700

 taaagtggag cgacaccaag ggagagaaca tcccggctgt ggaagcacct 750

 gtggttgcag atggagtggg cctgtatgca gtagcagcat ctgtgatcat 800

 gagaggcagc tctggtgggg gtgtatcctg catcatcaga aattccctcc 850

 tcggcctgga aaagacagcc agcatatcca tcgcagaccc cttcttcagg 900

 agcgcccagc cctggatcgc ggccctggca gggaccctgc ctatctcgtt 950

 gctgcttctc gcaggagcca gttacttctt gtggagacaa cagaaggaaa 1000

 aaattgctct gtccagggag acagaaagag agcgagagat gaaagaaatg 1050

 ggatacgctg caacagagca agaaataagc ctaagagaga agctccagga 1100

 ggaactcaag tggaggaaaa tccagtacat ggctcgtgga gagaagtctt 1150

 tggcctatca tgaatggaaa atggccctct tcaaacctgc ggatgtgatt 1200

 ctggatccag acacggcaaa cgccatcctc cttgtttctg aggaccagag 1250

 gagtgtgcag cgtgctgaag agccgcggga tctgccagac aaccctgaga 1300

 gatttgaatg gcgttactgt gtccttggct gtgaaaactt cacatcaggg 1350

 agacattact gggaggtgga agtgggggac agaaaagagt ggcatattgg 1400

 ggtatgtagt aagaacgtgg agaggaaaaa aggttgggtc aaaatgacac 1450

 cggagaacgg atactggact atgggcctga ctgatgggaa taagtatcgg 1500

 gctctcactg agcccagaac caacctgaaa cttcctgagc ctcctaggaa 1550

 agtggggatc ttcctggact atgagactgg agagatctcg ttctataatg 1600

 ccacagatgg atctcatatc tacacctttc cgcacgcctc tttctctgag 1650

 cctctatatc ctgttttcag aattttgacc ttggagccca ctgccctgac 1700

 catttgccca ataccaaaag aagtagagag ttcccccgat cctgacctag 1750

 tgcctgatca ttccctggag acaccactga ccccgggctt agctaatgaa 1800

 agtggggagc ctcaggctga agtaacatct ctgcttctcc ctgcccaccc 1850

 tggagctgag gtctcccctt ctgcaacaac caatcagaac cataagctac 1900

 aggcacgcac tgaagcactt tactgatatt cattccatta ttccatatga 1950

 cagttgtttt gagtttcgta ccaccttatt gtccccttat acagataagg 2000

 aaactggggt gcagaaaggt gaattaactt tacaaagtag acatgacaag 2050

 tgaacagcag agctgggatc taaacagcaa taactaacat taacagagaa 2100

 tttaaaatgt tcttagtgct gtgttataag ctttggtgga tgtcactcct 2150

 ttaatcctca caacaccctg tcgggtagtc atattttgca agtatggaag 2200

 ctgaggcagg gcaacatgaa gtaacttaca taattcatac agtaatttgt 2250

 gcagttggga gatgttcagc cttagtccct ggctaattgc ctgttctttt 2300

 ccagcctgat tttttttccc acaggaagag cccacatgta gccctgaggt 2350

 ttccttccca ggacagctgc agggtagaga tcattttaag tgcttgtgga 2400

 gttgacatcc ctattgactc tttcccagct gatatcagag acttagaccc 2450

 agcactcctt ggattagctc tgcagagtgt cttggttgag agaataacct 2500

 catagtacca acatgacatg tgacttggaa agagactaga ggccacactt 2550

 gataaatcat ggggcacaga tatgttccca cccaacaaat gtgataagtg 2600

 attgtgcagc cagagccagc cttccttcaa tcaaggtttc caggcagagc 2650

 aaatacccta gagattctct gtgatatagg aaatttggat caaggaagct 2700

 aaaagaatta cagggatgtt tttaatccca ctatggactc agtctcctgg 2750

 aaataggtct gtccactcct ggtcattggt ggatgttaaa cccatattcc 2800

 tttcaactgc tgcctgctag ggaaaactgc tcctcattat catcactatt 2850

 attgctcacc actgtatccc ctctacttgg caagtggttg tcaagttcta 2900

 gttgttcaat aaatgtgtta ataatgaaaa aaaaaaa 2937

<210> 1228
<211> 584
<212> PRT
<213> Homo sapien

<400> 1228
 Met Lys Met Ala Ser Ser Leu Ala Phe Leu Leu Leu Asn Phe His
   1               5                  10                  15

 Val Ser Leu Phe Leu Val Gln Leu Leu Thr Pro Cys Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Arg Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asp Leu
                 140                 145                 150

 His Ile Glu Val Lys Gly Tyr Glu Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Lys Trp Ser
                 170                 175                 180

 Asp Thr Lys Gly Glu Asn Ile Pro Ala Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Ala Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Ser Ser Gly Gly Gly Val Ser Cys Ile Ile Arg Asn Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Pro Trp Ile Ala Ala Leu Ala Gly Thr
                 245                 250                 255

 Leu Pro Ile Ser Leu Leu Leu Leu Ala Gly Ala Ser Tyr Phe Leu
                 260                 265                 270

 Trp Arg Gln Gln Lys Glu Lys Ile Ala Leu Ser Arg Glu Thr Glu
                 275                 280                 285

 Arg Glu Arg Glu Met Lys Glu Met Gly Tyr Ala Ala Thr Glu Gln
                 290                 295                 300

 Glu Ile Ser Leu Arg Glu Lys Leu Gln Glu Glu Leu Lys Trp Arg
                 305                 310                 315

 Lys Ile Gln Tyr Met Ala Arg Gly Glu Lys Ser Leu Ala Tyr His
                 320                 325                 330

 Glu Trp Lys Met Ala Leu Phe Lys Pro Ala Asp Val Ile Leu Asp
                 335                 340                 345

 Pro Asp Thr Ala Asn Ala Ile Leu Leu Val Ser Glu Asp Gln Arg
                 350                 355                 360

 Ser Val Gln Arg Ala Glu Glu Pro Arg Asp Leu Pro Asp Asn Pro
                 365                 370                 375

 Glu Arg Phe Glu Trp Arg Tyr Cys Val Leu Gly Cys Glu Asn Phe
                 380                 385                 390

 Thr Ser Gly Arg His Tyr Trp Glu Val Glu Val Gly Asp Arg Lys
                 395                 400                 405

 Glu Trp His Ile Gly Val Cys Ser Lys Asn Val Glu Arg Lys Lys
                 410                 415                 420

 Gly Trp Val Lys Met Thr Pro Glu Asn Gly Tyr Trp Thr Met Gly
                 425                 430                 435

 Leu Thr Asp Gly Asn Lys Tyr Arg Ala Leu Thr Glu Pro Arg Thr
                 440                 445                 450

 Asn Leu Lys Leu Pro Glu Pro Pro Arg Lys Val Gly Ile Phe Leu
                 455                 460                 465

 Asp Tyr Glu Thr Gly Glu Ile Ser Phe Tyr Asn Ala Thr Asp Gly
                 470                 475                 480

 Ser His Ile Tyr Thr Phe Pro His Ala Ser Phe Ser Glu Pro Leu
                 485                 490                 495

 Tyr Pro Val Phe Arg Ile Leu Thr Leu Glu Pro Thr Ala Leu Thr
                 500                 505                 510

 Ile Cys Pro Ile Pro Lys Glu Val Glu Ser Ser Pro Asp Pro Asp
                 515                 520                 525

 Leu Val Pro Asp His Ser Leu Glu Thr Pro Leu Thr Pro Gly Leu
                 530                 535                 540

 Ala Asn Glu Ser Gly Glu Pro Gln Ala Glu Val Thr Ser Leu Leu
                 545                 550                 555

 Leu Pro Ala His Pro Gly Ala Glu Val Ser Pro Ser Ala Thr Thr
                 560                 565                 570

 Asn Gln Asn His Lys Leu Gln Ala Arg Thr Glu Ala Leu Tyr
                 575                 580

<210> 1229
<211> 2937
<212> DNA
<213> Homo sapien

<400> 1229
 acgcgtccgc ttcggaatga gagactcaac cataatagaa agaatggaga 50

 actattaacc accattcttc agtgggctgt gattttcaga ggggaatact 100

 aagaaatggt tttccatact ggaacccaaa ggtaaagaca ctcaaggaca 150

 gacatttttg gcagagcata gatgaaaatg gcaagttccc tggctttcct 200

 tctgctcaac tttcatgtct ccctcttctt ggtccagctg ctcactcctt 250

 gctcagctca gttttctgtg cttggaccct ctgggcccat cctggccatg 300

 gtgggtgaag acgctgatct gccctgtcac ctgttcccga ccatgagtgc 350

 agagaccatg gagctgaggt gggtgagttc cagcctaagg caggtggtga 400

 acgtgtatgc agatggaaag gaagtggaag acaggcagag tgcaccatat 450

 cgagggagaa cttcgattct gcgggatggc atcactgcag ggaaggctgc 500

 tctccgaata cacaacgtca cagcctctga cagtggaaag tacttgtgtt 550

 atttccaaga tggtgacttc tacgaaaaag ccctggtgga gctgaaggtt 600

 gcagcattgg gttctgatct tcacattgaa gtgaagggtt atgaggatgg 650

 agggatccat ctggagtgca ggtccactgg ctggtacccc caaccccaaa 700

 taaagtggag cgacaccaag ggagagaaca tcccggctgt ggaagcacct 750

 gtggttgcag atggagtggg cctgtatgca gtagcagcat ctgtgatcat 800

 gagaggcagc tctggtgggg gtgtatcctg catcatcaga aattccctcc 850

 tcggcctgga aaagacagcc agcatatcca tcgcagaccc cttcttcagg 900

 agcgcccagc cctggatcgc ggccctggca gggaccctgc ctatctcgtt 950

 gctgcttctc gcaggagcca gttacttctt gtggagacaa cagaaggaaa 1000

 aaattgctct gtccagggag acagaaagag agcgagagat gaaagaaatg 1050

 ggatacgctg caacagagca agaaataagc ctaagagaga agctccagga 1100

 ggaactcaag tggaggaaaa tccagtacat ggctcgtgga gagaagtctt 1150

 tggcctatca tgaatggaaa atggccctct tcaaacctgc ggatgtgatt 1200

 ctggatccag acacggcaaa cgccatcctc cttgtttctg aggaccagag 1250

 gagtgtgcag cgtgctgaag agccgcggga tctgccagac aaccctgaga 1300

 gatttgaatg gcgttactgt gtccttggct gtgaaaactt cacatcaggg 1350

 agacattact gggaggtgga agtgggggac agaaaagagt ggcatattgg 1400

 ggtatgtagt aagaacgtgg agaggaaaaa aggttgggtc aaaatgacac 1450

 cggagaacgg atactggact atgggcctga ctgatgggaa taagtatcgg 1500

 gctctcactg agcccagaac caacctgaaa cttcctgagc ctcctaggaa 1550

 agtggggatc ttcctggact atgagactgg agagatctcg ttctataatg 1600

 ccacagatgg atctcatatc tacacctttc cgcacgcctc tttctctgag 1650

 cctctatatc ctgttttcag aattttgacc ttggagccca ctgccctgac 1700

 catttgccca ataccaaaag aagtagagag ttcccccgat cctgacctag 1750

 tgcctgatca ttccctggag acaccactga ccccgggctt agctaatgaa 1800

 agtggggagc ctcaggctga agtaacatct ctgcttctcc ctgcccaccc 1850

 tggagctgag gtctcccctt ctgcaacaac caatcagaac cataagctac 1900

 aggcacgcac tgaagcactt tactgatatt cattccatta ttccatatga 1950

 cagttgtttt gagtttcgta ccaccttatt gtccccttat acagataagg 2000

 aaactggggt gcagaaaggt gaattaactt tacaaagtag acatgacaag 2050

 tgaacagcag agctgggatc taaacagcaa taactaacat taacagagaa 2100

 tttaaaatgt tcttagtgct gtgttataag ctttggtgga tgtcactcct 2150

 ttaatcctca caacaccctg tcgggtagtc atattttgca agtatggaag 2200

 ctgaggcagg gcaacatgaa gtaacttaca taattcatac agtaatttgt 2250

 gcagttggga gatgttcagc cttagtccct ggctaattgc ctgttctttt 2300

 ccagcctgat tttttttccc acaggaagag cccacatgta gccctgaggt 2350

 ttccttccca ggacagctgc agggtagaga tcattttaag tgcttgtgga 2400

 gttgacatcc ctattgactc tttcccagct gatatcagag acttagaccc 2450

 agcactcctt ggattagctc tgcagagtgt cttggttgag agaataacct 2500

 catagtacca acatgacatg tgacttggaa agagactaga ggccacactt 2550

 gataaatcat ggggcacaga tatgttccca cccaacaaat gtgataagtg 2600

 attgtgcagc cagagccagc cttccttcaa tcaaggtttc caggcagagc 2650

 aaatacccta gagattctct gtgatatagg aaatttggat caaggaagct 2700

 aaaagaatta cagggatgtt tttaatccca ctatggactc agtctcctgg 2750

 aaataggtct gtccactcct ggtcattggt ggatgttaaa cccatattcc 2800

 tttcaactgc tgcctgctag ggaaaactgc tcctcattat catcactatt 2850

 attgctcacc actgtatccc ctctacttgg caagtggttg tcaagttcta 2900

 gttgttcaat aaatgtgtta ataatgaaaa aaaaaaa 2937

<210> 1230
<211> 584
<212> PRT
<213> Homo sapien

<400> 1230
 Met Lys Met Ala Ser Ser Leu Ala Phe Leu Leu Leu Asn Phe His
   1               5                  10                  15

 Val Ser Leu Phe Leu Val Gln Leu Leu Thr Pro Cys Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Arg Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asp Leu
                 140                 145                 150

 His Ile Glu Val Lys Gly Tyr Glu Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Lys Trp Ser
                 170                 175                 180

 Asp Thr Lys Gly Glu Asn Ile Pro Ala Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Ala Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Ser Ser Gly Gly Gly Val Ser Cys Ile Ile Arg Asn Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Pro Trp Ile Ala Ala Leu Ala Gly Thr
                 245                 250                 255

 Leu Pro Ile Ser Leu Leu Leu Leu Ala Gly Ala Ser Tyr Phe Leu
                 260                 265                 270

 Trp Arg Gln Gln Lys Glu Lys Ile Ala Leu Ser Arg Glu Thr Glu
                 275                 280                 285

 Arg Glu Arg Glu Met Lys Glu Met Gly Tyr Ala Ala Thr Glu Gln
                 290                 295                 300

 Glu Ile Ser Leu Arg Glu Lys Leu Gln Glu Glu Leu Lys Trp Arg
                 305                 310                 315

 Lys Ile Gln Tyr Met Ala Arg Gly Glu Lys Ser Leu Ala Tyr His
                 320                 325                 330

 Glu Trp Lys Met Ala Leu Phe Lys Pro Ala Asp Val Ile Leu Asp
                 335                 340                 345

 Pro Asp Thr Ala Asn Ala Ile Leu Leu Val Ser Glu Asp Gln Arg
                 350                 355                 360

 Ser Val Gln Arg Ala Glu Glu Pro Arg Asp Leu Pro Asp Asn Pro
                 365                 370                 375

 Glu Arg Phe Glu Trp Arg Tyr Cys Val Leu Gly Cys Glu Asn Phe
                 380                 385                 390

 Thr Ser Gly Arg His Tyr Trp Glu Val Glu Val Gly Asp Arg Lys
                 395                 400                 405

 Glu Trp His Ile Gly Val Cys Ser Lys Asn Val Glu Arg Lys Lys
                 410                 415                 420

 Gly Trp Val Lys Met Thr Pro Glu Asn Gly Tyr Trp Thr Met Gly
                 425                 430                 435

 Leu Thr Asp Gly Asn Lys Tyr Arg Ala Leu Thr Glu Pro Arg Thr
                 440                 445                 450

 Asn Leu Lys Leu Pro Glu Pro Pro Arg Lys Val Gly Ile Phe Leu
                 455                 460                 465

 Asp Tyr Glu Thr Gly Glu Ile Ser Phe Tyr Asn Ala Thr Asp Gly
                 470                 475                 480

 Ser His Ile Tyr Thr Phe Pro His Ala Ser Phe Ser Glu Pro Leu
                 485                 490                 495

 Tyr Pro Val Phe Arg Ile Leu Thr Leu Glu Pro Thr Ala Leu Thr
                 500                 505                 510

 Ile Cys Pro Ile Pro Lys Glu Val Glu Ser Ser Pro Asp Pro Asp
                 515                 520                 525

 Leu Val Pro Asp His Ser Leu Glu Thr Pro Leu Thr Pro Gly Leu
                 530                 535                 540

 Ala Asn Glu Ser Gly Glu Pro Gln Ala Glu Val Thr Ser Leu Leu
                 545                 550                 555

 Leu Pro Ala His Pro Gly Ala Glu Val Ser Pro Ser Ala Thr Thr
                 560                 565                 570

 Asn Gln Asn His Lys Leu Gln Ala Arg Thr Glu Ala Leu Tyr
                 575                 580

<210> 1231
<211> 3866
<212> DNA
<213> Homo sapien

<400> 1231
 ggaattcctt tttttttttt tttgagatgg agtttcactc ttgttggcca 50

 ggctggagtg caatggcaca atctcagctt actgcaacct ccgcctcccg 100

 ggttcaagcg attctcctgc ctcagcctct caagtagctg ggattacagg 150

 catgtgccac cacccctggc taactaattt cttttctatt tagtagagat 200

 ggggtttcac catgttggtc aggctggtct tgaactcctg acctcaggtg 250

 atccacttgc cttggcctcc caaagtgcta ggattacagc cgtgaaactg 300

 tgcctggctg attctttttt tgttgttgga tttttgaaac agggtctccc 350

 ttggtcgccc aggctggagt gcagtggtgc gatcttggct cactataacc 400

 tccacctcct ggtttcaagt gatcctccca ctttagcctc ctgagtagct 450

 gtgattacag gcgtgcacca ccacacccgg ctaatttttg tatttttatt 500

 agagacaggg tttcaccatg ttggccaggc tgttctcaaa ctcctggact 550

 caagggatcc gcctgcctcc acttcccaaa gtcccgagat tacaggtgtg 600

 agtcaccatg cctgacctta taattcttaa gtcatttttt ctggtccatt 650

 tcttccttag ggtcctcaca acaaatctgc attaggcggt acaataatcc 700

 ttaacttcat gattcacaaa aggaagatga agtgattcat gatttagaaa 750

 ggggaagtag taagcccact gcacactcct ggatgatgat cctaaatcca 800

 gatacagtaa aaatggggta tgggaaggta gaatacaaaa tttggtttaa 850

 attaattatc taaatatcta aaaacatttt tggatacatt gttgatgtga 900

 atgtaagact gtacagactt cctagaaaac agtttgggtt ccatcttttc 950

 atttccccag tgcagttttc tgtagaaatg gaatccgagg atttaagtgg 1000

 cagagaattg acaattgatt ccataatgaa caaagtgaga gacattaaaa 1050

 ataagtttaa aaatgaagac cttactgatg aactaagctt gaataaaatt 1100

 tctgctgata ctacagataa ctcgggaact gttaaccaaa ttatgatgat 1150

 ggcaaacaac ccagaggact ggttgagttt gttgctcaaa ctagagaaaa 1200

 acagtgttcc gctaagtgat gctcttttaa ataaattgat tggtcgttac 1250

 agtcaagcaa ttgaagcgct tcccccagat aaatatggcc aaaatgagag 1300

 ttttgctaga attcaagtga gatttgctga attaaaagct attcaagagc 1350

 cagatgatgc acgtgactac tttcaaatgg ccagagcaaa ctgcaagaaa 1400

 tttgcttttg ttcatatatc ttttgcacaa tttgaactgt cacaaggtaa 1450

 tgtcaaaaaa agtaaacaac ttcttcaaaa agctgtagaa cgtggagcag 1500

 taccactaga aatgctggaa attgccctgc ggaatttaaa cctccaaaaa 1550

 aagcagctgc tttcagagga ggaaaagaag aatttatcag catctacggt 1600

 attaactgcc caagaatcat tttccggttc acttgggcat ttacagaata 1650

 ggaacaacag ttgtgattcc agaggacaga ctactaaagc caggttttta 1700

 tatggagaga acatgccacc acaagatgca gaaataggtt accggaattc 1750

 attgagacaa actaacaaaa ctaaacagtc atgcccattt ggaagagtcc 1800

 cagttaacct tctaaatagc ccagattgtg atgtgaagac agatgattca 1850

 gttgtacctt gttttatgaa aagacaaacc tctagatcag aatgccgaga 1900

 tttggttgtg cctggatcta aaccaagtgg aaatgattcc tgtgaattaa 1950

 gaaatttaaa gtctgttcaa aatagtcatt tcaaggaacc tctggtgtca 2000

 gatgaaaaga gttctgaact tattattact gattcaataa ccctgaagaa 2050

 taaaacggaa tcaagtcttc tagctaaatt agaagaaact aaagagtatc 2100

 aagaaccaga ggttccagag agtaaccaga aacagtggca agctaagaga 2150

 aagtcagagt gtattaacca gaatcctgct gcatcttcaa atcactggca 2200

 gattccggag ttagcccgaa aagttaatac agagcagaaa cataccactt 2250

 ttgagcaacc tgtcttttca gtttcaaaac agtcaccacc aatatcaaca 2300

 tctaaatggt ttgacccaaa atctatttgt aagacaccaa gcagcaatac 2350

 cttggatgat tacatgagct gttttagaac tccagttgta aagaatgact 2400

 ttccacctgc ttgtcagttg tcaacacctt atggccaacc tgcctgtttc 2450

 cagcagcaac agcatcaaat acttgccact ccacttcaaa atttacaggt 2500

 tttagcatct tcttcagcaa atgaatgcat ttcggttaaa ggaagaattt 2550

 attccatatt aaagcagata ggaagtggag gttcaagcaa ggtatttcag 2600

 gtgttaaatg aaaagaaaca gatatatgct ataaaatatg tgaacttaga 2650

 agaagcagat aaccaaactc ttgatagtta ccggaacgaa atagcttatt 2700

 tgaataaact acaacaacac agtgataaga tcatccgact ttatgattat 2750

 gaaatcacgg accagtacat ctacatggta atggagtgtg gaaatattga 2800

 tcttaatagt tggcttaaaa agaaaaaatc cattgatcca tgggaacgca 2850

 agagttactg gaaaaatatg ttagaggcag ttcacacaat ccatcaacat 2900

 ggcattgttc acagtgatct taaaccagct aactttctga tagttgatgg 2950

 aatgctaaag ctaattgatt ttgggattgc aaaccaaatg caaccagata 3000

 caacaagtgt tgttaaagat tctcaggttg gcacagttaa ttatatgcca 3050

 ccagaagcaa tcaaagatat gtcttcctcc agagagaatg ggaaatctaa 3100

 gtcaaagata agccccaaaa gtgatgtttg gtccttagga tgtattttgt 3150

 actatatgac ttacgggaaa acaccatttc agcagataat taatcagatt 3200

 tctaaattac atgccataat tgatcctaat catgaaattg aatttcccga 3250

 tattccagag aaagatcttc aagatgtgtt aaagtgttgt ttaaaaaggg 3300

 acccaaaaca gaggatatcc attcctgagc tcctggctca tccatatgtt 3350

 caaattcaaa ctcatccagt taaccaaatg gccaagggaa ccactgaaga 3400

 aatgaaatat gttctgggcc aacttgttgg tctgaattct cctaactcca 3450

 ttttgaaagc tgctaaaact ttatatgaac actatagtgg tggtgaaagt 3500

 cataattctt catcctccaa gacttttgaa aaaaaaaggg gaaaaaaatg 3550

 atttgcagtt attcgtaatg tcagatagga ggtataaaat atattggact 3600

 gttatactct tgaatccctg tggaaatcta catttgaaga caacatcact 3650

 ctgaagtgtt atcagcaaaa aaaattcagt gagattatct ttaaaagaaa 3700

 actgtaaaaa tagcaaccac ttatggcact gtatatattg tagacttgtt 3750

 ttctctgttt tatgctcttg tgtaatctac ttgacatcat tttactcttg 3800

 gaatagtggg tggatagcaa gtatattcta aaaaactttg taaataaagt 3850

 tttgtggcta aaatga 3866

<210> 1232
<211> 841
<212> PRT
<213> Homo sapien

<400> 1232
 Met Asn Lys Val Arg Asp Ile Lys Asn Lys Phe Lys Asn Glu Asp
   1               5                  10                  15

 Leu Thr Asp Glu Leu Ser Leu Asn Lys Ile Ser Ala Asp Thr Thr
                  20                  25                  30

 Asp Asn Ser Gly Thr Val Asn Gln Ile Met Met Met Ala Asn Asn
                  35                  40                  45

 Pro Glu Asp Trp Leu Ser Leu Leu Leu Lys Leu Glu Lys Asn Ser
                  50                  55                  60

 Val Pro Leu Ser Asp Ala Leu Leu Asn Lys Leu Ile Gly Arg Tyr
                  65                  70                  75

 Ser Gln Ala Ile Glu Ala Leu Pro Pro Asp Lys Tyr Gly Gln Asn
                  80                  85                  90

 Glu Ser Phe Ala Arg Ile Gln Val Arg Phe Ala Glu Leu Lys Ala
                  95                 100                 105

 Ile Gln Glu Pro Asp Asp Ala Arg Asp Tyr Phe Gln Met Ala Arg
                 110                 115                 120

 Ala Asn Cys Lys Lys Phe Ala Phe Val His Ile Ser Phe Ala Gln
                 125                 130                 135

 Phe Glu Leu Ser Gln Gly Asn Val Lys Lys Ser Lys Gln Leu Leu
                 140                 145                 150

 Gln Lys Ala Val Glu Arg Gly Ala Val Pro Leu Glu Met Leu Glu
                 155                 160                 165

 Ile Ala Leu Arg Asn Leu Asn Leu Gln Lys Lys Gln Leu Leu Ser
                 170                 175                 180

 Glu Glu Glu Lys Lys Asn Leu Ser Ala Ser Thr Val Leu Thr Ala
                 185                 190                 195

 Gln Glu Ser Phe Ser Gly Ser Leu Gly His Leu Gln Asn Arg Asn
                 200                 205                 210

 Asn Ser Cys Asp Ser Arg Gly Gln Thr Thr Lys Ala Arg Phe Leu
                 215                 220                 225

 Tyr Gly Glu Asn Met Pro Pro Gln Asp Ala Glu Ile Gly Tyr Arg
                 230                 235                 240

 Asn Ser Leu Arg Gln Thr Asn Lys Thr Lys Gln Ser Cys Pro Phe
                 245                 250                 255

 Gly Arg Val Pro Val Asn Leu Leu Asn Ser Pro Asp Cys Asp Val
                 260                 265                 270

 Lys Thr Asp Asp Ser Val Val Pro Cys Phe Met Lys Arg Gln Thr
                 275                 280                 285

 Ser Arg Ser Glu Cys Arg Asp Leu Val Val Pro Gly Ser Lys Pro
                 290                 295                 300

 Ser Gly Asn Asp Ser Cys Glu Leu Arg Asn Leu Lys Ser Val Gln
                 305                 310                 315

 Asn Ser His Phe Lys Glu Pro Leu Val Ser Asp Glu Lys Ser Ser
                 320                 325                 330

 Glu Leu Ile Ile Thr Asp Ser Ile Thr Leu Lys Asn Lys Thr Glu
                 335                 340                 345

 Ser Ser Leu Leu Ala Lys Leu Glu Glu Thr Lys Glu Tyr Gln Glu
                 350                 355                 360

 Pro Glu Val Pro Glu Ser Asn Gln Lys Gln Trp Gln Ala Lys Arg
                 365                 370                 375

 Lys Ser Glu Cys Ile Asn Gln Asn Pro Ala Ala Ser Ser Asn His
                 380                 385                 390

 Trp Gln Ile Pro Glu Leu Ala Arg Lys Val Asn Thr Glu Gln Lys
                 395                 400                 405

 His Thr Thr Phe Glu Gln Pro Val Phe Ser Val Ser Lys Gln Ser
                 410                 415                 420

 Pro Pro Ile Ser Thr Ser Lys Trp Phe Asp Pro Lys Ser Ile Cys
                 425                 430                 435

 Lys Thr Pro Ser Ser Asn Thr Leu Asp Asp Tyr Met Ser Cys Phe
                 440                 445                 450

 Arg Thr Pro Val Val Lys Asn Asp Phe Pro Pro Ala Cys Gln Leu
                 455                 460                 465

 Ser Thr Pro Tyr Gly Gln Pro Ala Cys Phe Gln Gln Gln Gln His
                 470                 475                 480

 Gln Ile Leu Ala Thr Pro Leu Gln Asn Leu Gln Val Leu Ala Ser
                 485                 490                 495

 Ser Ser Ala Asn Glu Cys Ile Ser Val Lys Gly Arg Ile Tyr Ser
                 500                 505                 510

 Ile Leu Lys Gln Ile Gly Ser Gly Gly Ser Ser Lys Val Phe Gln
                 515                 520                 525

 Val Leu Asn Glu Lys Lys Gln Ile Tyr Ala Ile Lys Tyr Val Asn
                 530                 535                 540

 Leu Glu Glu Ala Asp Asn Gln Thr Leu Asp Ser Tyr Arg Asn Glu
                 545                 550                 555

 Ile Ala Tyr Leu Asn Lys Leu Gln Gln His Ser Asp Lys Ile Ile
                 560                 565                 570

 Arg Leu Tyr Asp Tyr Glu Ile Thr Asp Gln Tyr Ile Tyr Met Val
                 575                 580                 585

 Met Glu Cys Gly Asn Ile Asp Leu Asn Ser Trp Leu Lys Lys Lys
                 590                 595                 600

 Lys Ser Ile Asp Pro Trp Glu Arg Lys Ser Tyr Trp Lys Asn Met
                 605                 610                 615

 Leu Glu Ala Val His Thr Ile His Gln His Gly Ile Val His Ser
                 620                 625                 630

 Asp Leu Lys Pro Ala Asn Phe Leu Ile Val Asp Gly Met Leu Lys
                 635                 640                 645

 Leu Ile Asp Phe Gly Ile Ala Asn Gln Met Gln Pro Asp Thr Thr
                 650                 655                 660

 Ser Val Val Lys Asp Ser Gln Val Gly Thr Val Asn Tyr Met Pro
                 665                 670                 675

 Pro Glu Ala Ile Lys Asp Met Ser Ser Ser Arg Glu Asn Gly Lys
                 680                 685                 690

 Ser Lys Ser Lys Ile Ser Pro Lys Ser Asp Val Trp Ser Leu Gly
                 695                 700                 705

 Cys Ile Leu Tyr Tyr Met Thr Tyr Gly Lys Thr Pro Phe Gln Gln
                 710                 715                 720

 Ile Ile Asn Gln Ile Ser Lys Leu His Ala Ile Ile Asp Pro Asn
                 725                 730                 735

 His Glu Ile Glu Phe Pro Asp Ile Pro Glu Lys Asp Leu Gln Asp
                 740                 745                 750

 Val Leu Lys Cys Cys Leu Lys Arg Asp Pro Lys Gln Arg Ile Ser
                 755                 760                 765

 Ile Pro Glu Leu Leu Ala His Pro Tyr Val Gln Ile Gln Thr His
                 770                 775                 780

 Pro Val Asn Gln Met Ala Lys Gly Thr Thr Glu Glu Met Lys Tyr
                 785                 790                 795

 Val Leu Gly Gln Leu Val Gly Leu Asn Ser Pro Asn Ser Ile Leu
                 800                 805                 810

 Lys Ala Ala Lys Thr Leu Tyr Glu His Tyr Ser Gly Gly Glu Ser
                 815                 820                 825

 His Asn Ser Ser Ser Ser Lys Thr Phe Glu Lys Lys Arg Gly Lys
                 830                 835                 840

 Lys


<210> 1233
<211> 2470
<212> DNA
<213> Homo sapien

<400> 1233
 ttggcgggcg gaagcggcca caacccggcg atcgaaaaga ttcttaggaa 50

 cgccgtacca gccgcgtctc tcaggacagc aggcccctgt ccttctgtcg 100

 ggcgccgctc agccgtgccc tccgcccctc aggttctttt tctaattcca 150

 aataaacttg caagaggact atgaaagatt atgatgaact tctcaaatat 200

 tatgaattac atgaaactat tgggacaggt ggctttgcaa aggtcaaact 250

 tgcctgccat atccttactg gagagatggt agctataaaa atcatggata 300

 aaaacacact agggagtgat ttgccccgga tcaaaacgga gattgaggcc 350

 ttgaagaacc tgagacatca gcatatatgt caactctacc atgtgctaga 400

 gacagccaac aaaatattca tggttcttga gtactgccct ggaggagagc 450

 tgtttgacta tataatttcc caggatcgcc tgtcagaaga ggagacccgg 500

 gttgtcttcc gtcagatagt atctgctgtt gcttatgtgc acagccaggg 550

 ctatgctcac agggacctca agccagaaaa tttgctgttt gatgaatatc 600

 ataaattaaa gctgattgac tttggtctct gtgcaaaacc caagggtaac 650

 aaggattacc atctacagac atgctgtggg agtctggctt atgcagcacc 700

 tgagttaata caaggcaaat catatcttgg atcagaggca gatgtttgga 750

 gcatgggcat actgttatat gttcttatgt gtggatttct accatttgat 800

 gatgataatg taatggcttt atacaagaag attatgagag gaaaatatga 850

 tgttcccaag tggctctctc ccagtagcat tctgcttctt caacaaatgc 900

 tgcaggtgga cccaaagaaa cggatttcta tgaaaaatct attgaaccat 950

 ccctggatca tgcaagatta caactatcct gttgagtggc aaagcaagaa 1000

 tccttttatt cacctcgatg atgattgcgt aacagaactt tctgtacatc 1050

 acagaaacaa caggcaaaca atggaggatt taatttcact gtggcagtat 1100

 gatcacctca cggctaccta tcttctgctt ctagccaaga aggctcgggg 1150

 aaaaccagtt cgtttaaggc tttcttcttt ctcctgtgga caagccagtg 1200

 ctaccccatt cacagacatc aagtcaaata attggagtct ggaagatgtg 1250

 accgcaagtg ataaaaatta tgtggcggga ttaatagact atgattggtg 1300

 tgaagatgat ttatcaacag gtgctgctac tccccgaaca tcacagttta 1350

 ccaagtactg gacagaatca aatggggtgg aatctaaatc attaactcca 1400

 gccttatgca gaacacctgc aaataaatta aagaacaaag aaaatgtata 1450

 tactcctaag tctgctgtaa agaatgaaga gtactttatg tttcctgagc 1500

 caaagactcc agttaataag aaccagcata agagagaaat actcactacg 1550

 ccaaatcgtt acactacacc ctcaaaagct agaaaccagt gcctgaaaga 1600

 aactccaatt aaaataccag taaattcaac aggaacagac aagttaatga 1650

 caggtgtcat tagccctgag aggcggtgcc gctcagtgga attggatctc 1700

 aaccaagcac atatggagga gactccaaaa agaaagggag ccaaagtgtt 1750

 tgggagcctt gaaagggggt tggataaggt tatcactgtg ctcaccagga 1800

 gcaaaaggaa gggttctgcc agagacgggc ccagaagact aaagcttcac 1850

 tataatgtga ctacaactag attagtgaat ccagatcaac tgttgaatga 1900

 aataatgtct attcttccaa agaagcatgt tgactttgta caaaagggtt 1950

 atacactgaa gtgtcaaaca cagtcagatt ttgggaaagt gacaatgcaa 2000

 tttgaattag aagtgtgcca gcttcaaaaa cccgatgtgg tgggtatcag 2050

 gaggcagcgg cttaagggcg atgcctgggt ttacaaaaga ttagtggaag 2100

 acatcctatc tagctgcaag gtataattga tggattcttc catcctgccg 2150

 gatgagtgtg ggtgtgatac agcctacata aagactgtta tgatcgcttt 2200

 gattttaaag ttcattggaa ctaccaactt gtttctaaag agctatctta 2250

 agaccaatat ctctttgttt ttaaacaaaa gatattattt tgtgtatgaa 2300

 tctaaatcaa gcccatctgt cattatgtta ctgtcttttt taatcatgtg 2350

 gttttgtata ttaataattg ttgactttct tagattcact tccatatgtg 2400

 aatgtaagct cttaactatg tctctttgta atgtgtaatt tctttctgaa 2450

 ataaaaccat ttgtgaatat 2470

<210> 1234
<211> 651
<212> PRT
<213> Homo sapien

<400> 1234
 Met Lys Asp Tyr Asp Glu Leu Leu Lys Tyr Tyr Glu Leu His Glu
   1               5                  10                  15

 Thr Ile Gly Thr Gly Gly Phe Ala Lys Val Lys Leu Ala Cys His
                  20                  25                  30

 Ile Leu Thr Gly Glu Met Val Ala Ile Lys Ile Met Asp Lys Asn
                  35                  40                  45

 Thr Leu Gly Ser Asp Leu Pro Arg Ile Lys Thr Glu Ile Glu Ala
                  50                  55                  60

 Leu Lys Asn Leu Arg His Gln His Ile Cys Gln Leu Tyr His Val
                  65                  70                  75

 Leu Glu Thr Ala Asn Lys Ile Phe Met Val Leu Glu Tyr Cys Pro
                  80                  85                  90

 Gly Gly Glu Leu Phe Asp Tyr Ile Ile Ser Gln Asp Arg Leu Ser
                  95                 100                 105

 Glu Glu Glu Thr Arg Val Val Phe Arg Gln Ile Val Ser Ala Val
                 110                 115                 120

 Ala Tyr Val His Ser Gln Gly Tyr Ala His Arg Asp Leu Lys Pro
                 125                 130                 135

 Glu Asn Leu Leu Phe Asp Glu Tyr His Lys Leu Lys Leu Ile Asp
                 140                 145                 150

 Phe Gly Leu Cys Ala Lys Pro Lys Gly Asn Lys Asp Tyr His Leu
                 155                 160                 165

 Gln Thr Cys Cys Gly Ser Leu Ala Tyr Ala Ala Pro Glu Leu Ile
                 170                 175                 180

 Gln Gly Lys Ser Tyr Leu Gly Ser Glu Ala Asp Val Trp Ser Met
                 185                 190                 195

 Gly Ile Leu Leu Tyr Val Leu Met Cys Gly Phe Leu Pro Phe Asp
                 200                 205                 210

 Asp Asp Asn Val Met Ala Leu Tyr Lys Lys Ile Met Arg Gly Lys
                 215                 220                 225

 Tyr Asp Val Pro Lys Trp Leu Ser Pro Ser Ser Ile Leu Leu Leu
                 230                 235                 240

 Gln Gln Met Leu Gln Val Asp Pro Lys Lys Arg Ile Ser Met Lys
                 245                 250                 255

 Asn Leu Leu Asn His Pro Trp Ile Met Gln Asp Tyr Asn Tyr Pro
                 260                 265                 270

 Val Glu Trp Gln Ser Lys Asn Pro Phe Ile His Leu Asp Asp Asp
                 275                 280                 285

 Cys Val Thr Glu Leu Ser Val His His Arg Asn Asn Arg Gln Thr
                 290                 295                 300

 Met Glu Asp Leu Ile Ser Leu Trp Gln Tyr Asp His Leu Thr Ala
                 305                 310                 315

 Thr Tyr Leu Leu Leu Leu Ala Lys Lys Ala Arg Gly Lys Pro Val
                 320                 325                 330

 Arg Leu Arg Leu Ser Ser Phe Ser Cys Gly Gln Ala Ser Ala Thr
                 335                 340                 345

 Pro Phe Thr Asp Ile Lys Ser Asn Asn Trp Ser Leu Glu Asp Val
                 350                 355                 360

 Thr Ala Ser Asp Lys Asn Tyr Val Ala Gly Leu Ile Asp Tyr Asp
                 365                 370                 375

 Trp Cys Glu Asp Asp Leu Ser Thr Gly Ala Ala Thr Pro Arg Thr
                 380                 385                 390

 Ser Gln Phe Thr Lys Tyr Trp Thr Glu Ser Asn Gly Val Glu Ser
                 395                 400                 405

 Lys Ser Leu Thr Pro Ala Leu Cys Arg Thr Pro Ala Asn Lys Leu
                 410                 415                 420

 Lys Asn Lys Glu Asn Val Tyr Thr Pro Lys Ser Ala Val Lys Asn
                 425                 430                 435

 Glu Glu Tyr Phe Met Phe Pro Glu Pro Lys Thr Pro Val Asn Lys
                 440                 445                 450

 Asn Gln His Lys Arg Glu Ile Leu Thr Thr Pro Asn Arg Tyr Thr
                 455                 460                 465

 Thr Pro Ser Lys Ala Arg Asn Gln Cys Leu Lys Glu Thr Pro Ile
                 470                 475                 480

 Lys Ile Pro Val Asn Ser Thr Gly Thr Asp Lys Leu Met Thr Gly
                 485                 490                 495

 Val Ile Ser Pro Glu Arg Arg Cys Arg Ser Val Glu Leu Asp Leu
                 500                 505                 510

 Asn Gln Ala His Met Glu Glu Thr Pro Lys Arg Lys Gly Ala Lys
                 515                 520                 525

 Val Phe Gly Ser Leu Glu Arg Gly Leu Asp Lys Val Ile Thr Val
                 530                 535                 540

 Leu Thr Arg Ser Lys Arg Lys Gly Ser Ala Arg Asp Gly Pro Arg
                 545                 550                 555

 Arg Leu Lys Leu His Tyr Asn Val Thr Thr Thr Arg Leu Val Asn
                 560                 565                 570

 Pro Asp Gln Leu Leu Asn Glu Ile Met Ser Ile Leu Pro Lys Lys
                 575                 580                 585

 His Val Asp Phe Val Gln Lys Gly Tyr Thr Leu Lys Cys Gln Thr
                 590                 595                 600

 Gln Ser Asp Phe Gly Lys Val Thr Met Gln Phe Glu Leu Glu Val
                 605                 610                 615

 Cys Gln Leu Gln Lys Pro Asp Val Val Gly Ile Arg Arg Gln Arg
                 620                 625                 630

 Leu Lys Gly Asp Ala Trp Val Tyr Lys Arg Leu Val Glu Asp Ile
                 635                 640                 645

 Leu Ser Ser Cys Lys Val
                 650

<210> 1235
<211> 3242
<212> DNA
<213> Homo sapien

<400> 1235
 gagcagccaa aaggcccgcg gagtcgcgct gggccgcccc ggcgcagctg 50

 aaccgggggc cgcgcctgcc aggccgacgg gtctggccca gcctggcgcc 100

 aaggggttcg tgcgctgtgg agacgcggag ggtcgaggcg gcgcggcctg 150

 agtgaaaccc aatggaaaaa gcatgacatt tagaagtaga agacttagct 200

 tcaaatccct actccttcac ttactaattt tgtgatttgg aaatatccgc 250

 gcaagatgtt gacgttgcag acttggctag tgcaagcctt gtttattttc 300

 ctcaccactg aatctacagg tgaacttcta gatccatgtg gttatatcag 350

 tcctgaatct ccagttgtac aacttcattc taatttcact gcagtttgtg 400

 tgctaaagga aaaatgtatg gattattttc atgtaaatgc taattacatt 450

 gtctggaaaa caaaccattt tactattcct aaggagcaat atactatcat 500

 aaacagaaca gcatccagtg tcacctttac agatatagct tcattaaata 550

 ttcagctcac ttgcaacatt cttacattcg gacagcttga acagaatgtt 600

 tatggaatca caataatttc aggcttgcct ccagaaaaac ctaaaaattt 650

 gagttgcatt gtgaacgagg ggaagaaaat gaggtgtgag tgggatggtg 700

 gaagggaaac acacttggag acaaacttca ctttaaaatc tgaatgggca 750

 acacacaagt ttgctgattg caaagcaaaa cgtgacaccc ccacctcatg 800

 cactgttgat tattctactg tgtattttgt caacattgaa gtctgggtag 850

 aagcagagaa tgcccttggg aaggttacat cagatcatat caattttgat 900

 cctgtatata aagtgaagcc caatccgcca cataatttat cagtgatcaa 950

 ctcagaggaa ctgtctagta tcttaaaatt gacatggacc aacccaagta 1000

 ttaagagtgt tataatacta aaatataaca ttcaatatag gaccaaagat 1050

 gcctcaactt ggagccagat tcctcctgaa gacacagcat ccacccgatc 1100

 ttcattcact gtccaagacc ttaaaccttt tacagaatat gtgtttagga 1150

 ttcgctgtat gaaggaagat ggtaagggat actggagtga ctggagtgaa 1200

 gaagcaagtg ggatcaccta tgaagataga ccatctaaag caccaagttt 1250

 ctggtataaa atagatccat cccatactca aggctacaga actgtacaac 1300

 tcgtgtggaa gacattgcct ccttttgaag ccaatggaaa aatcttggat 1350

 tatgaagtga ctctcacaag atggaaatca catttacaaa attacacagt 1400

 taatgccaca aaactgacag taaatctcac aaatgatcgc tatctagcaa 1450

 ccctaacagt aagaaatctt gttggcaaat cagatgcagc tgttttaact 1500

 atccctgcct gtgactttca agctactcac cctgtaatgg atcttaaagc 1550

 attccccaaa gataacatgc tttgggtgga atggactact ccaagggaat 1600

 ctgtaaagaa atatatactt gagtggtgtg tgttatcaga taaagcaccc 1650

 tgtatcacag actggcaaca agaagatggt accgtgcatc gcacctattt 1700

 aagagggaac ttagcagaga gcaaatgcta tttgataaca gttactccag 1750

 tatatgctga tggaccagga agccctgaat ccataaaggc ataccttaaa 1800

 caagctccac cttccaaagg acctactgtt cggacaaaaa aagtagggaa 1850

 aaacgaagct gtcttagagt gggaccaact tcctgttgat gttcagaatg 1900

 gatttatcag aaattatact atattttata gaaccatcat tggaaatgaa 1950

 actgctgtga atgtggattc ttcccacaca gaatatacat tgtcctcttt 2000

 gactagtgac acattgtaca tggtacgaat ggcagcatac acagatgaag 2050

 gtgggaagga tggtccagaa ttcactttta ctaccccaaa gtttgctcaa 2100

 ggagaaattg aagccatagt cgtgcctgtt tgcttagcat tcctattgac 2150

 aactcttctg ggagtgctgt tctgctttaa taagcgagac ctaattaaaa 2200

 aacacatctg gcctaatgtt ccagatcctt caaagagtca tattgcccag 2250

 tggtcacctc acactcctcc aaggcacaat tttaattcaa aagatcaaat 2300

 gtattcagat ggcaatttca ctgatgtaag tgttgtggaa atagaagcaa 2350

 atgacaaaaa gccttttcca gaagatctga aatcattgga cctgttcaaa 2400

 aaggaaaaaa ttaatactga aggacacagc agtggtattg gggggtcttc 2450

 atgcatgtca tcttctaggc caagcatttc tagcagtgat gaaaatgaat 2500

 cttcacaaaa cacttcgagc actgtccagt attctaccgt ggtacacagt 2550

 ggctacagac accaagttcc gtcagtccaa gtcttctcaa gatccgagtc 2600

 tacccagccc ttgttagatt cagaggagcg gccagaagat ctacaattag 2650

 tagatcatgt agatggcggt gatggtattt tgcccaggca acagtacttc 2700

 aaacagaact gcagtcagca tgaatccagt ccagatattt cacattttga 2750

 aaggtcaaag caagtttcat cagtcaatga ggaagatttt gttagactta 2800

 aacagcagat ttcagatcat atttcacaat cctgtggatc tgggcaaatg 2850

 aaaatgtttc aggaagtttc tgcagcagat gcttttggtc caggtactga 2900

 gggacaagta gaaagatttg aaacagttgg catggaggct gcgactgatg 2950

 aaggcatgcc taaaagttac ttaccacaga ctgtacggca aggcggctac 3000

 atgcctcagt gaaggactag tagttcctgc tacaacttca gcagtaccta 3050

 taaagtaaag ctaaaatgat tttatctgtg aattcagatt ttaaaaagtc 3100

 ttcactctct gaagatgatc atttgccctt aaggacaaaa atgaactgaa 3150

 gtttcacatg agctatttcc attccagaat atctgggatt ctactttaag 3200

 cactacataa actgacttta tcctcagaaa aaaaaaaaaa aa 3242

<210> 1236
<211> 918
<212> PRT
<213> Homo sapien

<400> 1236
 Met Leu Thr Leu Gln Thr Trp Leu Val Gln Ala Leu Phe Ile Phe
   1               5                  10                  15

 Leu Thr Thr Glu Ser Thr Gly Glu Leu Leu Asp Pro Cys Gly Tyr
                  20                  25                  30

 Ile Ser Pro Glu Ser Pro Val Val Gln Leu His Ser Asn Phe Thr
                  35                  40                  45

 Ala Val Cys Val Leu Lys Glu Lys Cys Met Asp Tyr Phe His Val
                  50                  55                  60

 Asn Ala Asn Tyr Ile Val Trp Lys Thr Asn His Phe Thr Ile Pro
                  65                  70                  75

 Lys Glu Gln Tyr Thr Ile Ile Asn Arg Thr Ala Ser Ser Val Thr
                  80                  85                  90

 Phe Thr Asp Ile Ala Ser Leu Asn Ile Gln Leu Thr Cys Asn Ile
                  95                 100                 105

 Leu Thr Phe Gly Gln Leu Glu Gln Asn Val Tyr Gly Ile Thr Ile
                 110                 115                 120

 Ile Ser Gly Leu Pro Pro Glu Lys Pro Lys Asn Leu Ser Cys Ile
                 125                 130                 135

 Val Asn Glu Gly Lys Lys Met Arg Cys Glu Trp Asp Gly Gly Arg
                 140                 145                 150

 Glu Thr His Leu Glu Thr Asn Phe Thr Leu Lys Ser Glu Trp Ala
                 155                 160                 165

 Thr His Lys Phe Ala Asp Cys Lys Ala Lys Arg Asp Thr Pro Thr
                 170                 175                 180

 Ser Cys Thr Val Asp Tyr Ser Thr Val Tyr Phe Val Asn Ile Glu
                 185                 190                 195

 Val Trp Val Glu Ala Glu Asn Ala Leu Gly Lys Val Thr Ser Asp
                 200                 205                 210

 His Ile Asn Phe Asp Pro Val Tyr Lys Val Lys Pro Asn Pro Pro
                 215                 220                 225

 His Asn Leu Ser Val Ile Asn Ser Glu Glu Leu Ser Ser Ile Leu
                 230                 235                 240

 Lys Leu Thr Trp Thr Asn Pro Ser Ile Lys Ser Val Ile Ile Leu
                 245                 250                 255

 Lys Tyr Asn Ile Gln Tyr Arg Thr Lys Asp Ala Ser Thr Trp Ser
                 260                 265                 270

 Gln Ile Pro Pro Glu Asp Thr Ala Ser Thr Arg Ser Ser Phe Thr
                 275                 280                 285

 Val Gln Asp Leu Lys Pro Phe Thr Glu Tyr Val Phe Arg Ile Arg
                 290                 295                 300

 Cys Met Lys Glu Asp Gly Lys Gly Tyr Trp Ser Asp Trp Ser Glu
                 305                 310                 315

 Glu Ala Ser Gly Ile Thr Tyr Glu Asp Arg Pro Ser Lys Ala Pro
                 320                 325                 330

 Ser Phe Trp Tyr Lys Ile Asp Pro Ser His Thr Gln Gly Tyr Arg
                 335                 340                 345

 Thr Val Gln Leu Val Trp Lys Thr Leu Pro Pro Phe Glu Ala Asn
                 350                 355                 360

 Gly Lys Ile Leu Asp Tyr Glu Val Thr Leu Thr Arg Trp Lys Ser
                 365                 370                 375

 His Leu Gln Asn Tyr Thr Val Asn Ala Thr Lys Leu Thr Val Asn
                 380                 385                 390

 Leu Thr Asn Asp Arg Tyr Leu Ala Thr Leu Thr Val Arg Asn Leu
                 395                 400                 405

 Val Gly Lys Ser Asp Ala Ala Val Leu Thr Ile Pro Ala Cys Asp
                 410                 415                 420

 Phe Gln Ala Thr His Pro Val Met Asp Leu Lys Ala Phe Pro Lys
                 425                 430                 435

 Asp Asn Met Leu Trp Val Glu Trp Thr Thr Pro Arg Glu Ser Val
                 440                 445                 450

 Lys Lys Tyr Ile Leu Glu Trp Cys Val Leu Ser Asp Lys Ala Pro
                 455                 460                 465

 Cys Ile Thr Asp Trp Gln Gln Glu Asp Gly Thr Val His Arg Thr
                 470                 475                 480

 Tyr Leu Arg Gly Asn Leu Ala Glu Ser Lys Cys Tyr Leu Ile Thr
                 485                 490                 495

 Val Thr Pro Val Tyr Ala Asp Gly Pro Gly Ser Pro Glu Ser Ile
                 500                 505                 510

 Lys Ala Tyr Leu Lys Gln Ala Pro Pro Ser Lys Gly Pro Thr Val
                 515                 520                 525

 Arg Thr Lys Lys Val Gly Lys Asn Glu Ala Val Leu Glu Trp Asp
                 530                 535                 540

 Gln Leu Pro Val Asp Val Gln Asn Gly Phe Ile Arg Asn Tyr Thr
                 545                 550                 555

 Ile Phe Tyr Arg Thr Ile Ile Gly Asn Glu Thr Ala Val Asn Val
                 560                 565                 570

 Asp Ser Ser His Thr Glu Tyr Thr Leu Ser Ser Leu Thr Ser Asp
                 575                 580                 585

 Thr Leu Tyr Met Val Arg Met Ala Ala Tyr Thr Asp Glu Gly Gly
                 590                 595                 600

 Lys Asp Gly Pro Glu Phe Thr Phe Thr Thr Pro Lys Phe Ala Gln
                 605                 610                 615

 Gly Glu Ile Glu Ala Ile Val Val Pro Val Cys Leu Ala Phe Leu
                 620                 625                 630

 Leu Thr Thr Leu Leu Gly Val Leu Phe Cys Phe Asn Lys Arg Asp
                 635                 640                 645

 Leu Ile Lys Lys His Ile Trp Pro Asn Val Pro Asp Pro Ser Lys
                 650                 655                 660

 Ser His Ile Ala Gln Trp Ser Pro His Thr Pro Pro Arg His Asn
                 665                 670                 675

 Phe Asn Ser Lys Asp Gln Met Tyr Ser Asp Gly Asn Phe Thr Asp
                 680                 685                 690

 Val Ser Val Val Glu Ile Glu Ala Asn Asp Lys Lys Pro Phe Pro
                 695                 700                 705

 Glu Asp Leu Lys Ser Leu Asp Leu Phe Lys Lys Glu Lys Ile Asn
                 710                 715                 720

 Thr Glu Gly His Ser Ser Gly Ile Gly Gly Ser Ser Cys Met Ser
                 725                 730                 735

 Ser Ser Arg Pro Ser Ile Ser Ser Ser Asp Glu Asn Glu Ser Ser
                 740                 745                 750

 Gln Asn Thr Ser Ser Thr Val Gln Tyr Ser Thr Val Val His Ser
                 755                 760                 765

 Gly Tyr Arg His Gln Val Pro Ser Val Gln Val Phe Ser Arg Ser
                 770                 775                 780

 Glu Ser Thr Gln Pro Leu Leu Asp Ser Glu Glu Arg Pro Glu Asp
                 785                 790                 795

 Leu Gln Leu Val Asp His Val Asp Gly Gly Asp Gly Ile Leu Pro
                 800                 805                 810

 Arg Gln Gln Tyr Phe Lys Gln Asn Cys Ser Gln His Glu Ser Ser
                 815                 820                 825

 Pro Asp Ile Ser His Phe Glu Arg Ser Lys Gln Val Ser Ser Val
                 830                 835                 840

 Asn Glu Glu Asp Phe Val Arg Leu Lys Gln Gln Ile Ser Asp His
                 845                 850                 855

 Ile Ser Gln Ser Cys Gly Ser Gly Gln Met Lys Met Phe Gln Glu
                 860                 865                 870

 Val Ser Ala Ala Asp Ala Phe Gly Pro Gly Thr Glu Gly Gln Val
                 875                 880                 885

 Glu Arg Phe Glu Thr Val Gly Met Glu Ala Ala Thr Asp Glu Gly
                 890                 895                 900

 Met Pro Lys Ser Tyr Leu Pro Gln Thr Val Arg Gln Gly Gly Tyr
                 905                 910                 915

 Met Pro Gln


<210> 1237
<211> 3159
<212> DNA
<213> Homo sapien

<400> 1237
 gagcagccaa aaggcccgcg gagtcgcgct gggccgcccc ggcgcagctg 50

 aaccgggggc cgcgcctgcc aggccgacgg gtctggccca gcctggcgcc 100

 aaggggttcg tgcgctgtgg agacgcggag ggtcgaggcg gcgcggcctg 150

 agtgaaaccc aatggaaaaa gcatgacatt tagaagtaga agacttagct 200

 tcaaatccct actccttcac ttactaattt tgtgatttgg aaatatccgc 250

 gcaagatgtt gacgttgcag acttggctag tgcaagcctt gtttattttc 300

 ctcaccactg aatctacagg tgaacttcta gatccatgtg gttatatcag 350

 tcctgaatct ccagttgtac aacttcattc taatttcact gcagtttgtg 400

 tgctaaagga aaaatgtatg gattattttc atgtaaatgc taattacatt 450

 gtctggaaaa caaaccattt tactattcct aaggagcaat atactatcat 500

 aaacagaaca gcatccagtg tcacctttac agatatagct tcattaaata 550

 ttcagctcac ttgcaacatt cttacattcg gacagcttga acagaatgtt 600

 tatggaatca caataatttc aggcttgcct ccagaaaaac ctaaaaattt 650

 gagttgcatt gtgaacgagg ggaagaaaat gaggtgtgag tgggatggtg 700

 gaagggaaac acacttggag acaaacttca ctttaaaatc tgaatgggca 750

 acacacaagt ttgctgattg caaagcaaaa cgtgacaccc ccacctcatg 800

 cactgttgat tattctactg tgtattttgt caacattgaa gtctgggtag 850

 aagcagagaa tgcccttggg aaggttacat cagatcatat caattttgat 900

 cctgtatata aagtgaagcc caatccgcca cataatttat cagtgatcaa 950

 ctcagaggaa ctgtctagta tcttaaaatt gacatggacc aacccaagta 1000

 ttaagagtgt tataatacta aaatataaca ttcaatatag gaccaaagat 1050

 gcctcaactt ggagccagat tcctcctgaa gacacagcat ccacccgatc 1100

 ttcattcact gtccaagacc ttaaaccttt tacagaatat gtgtttagga 1150

 ttcgctgtat gaaggaagat ggtaagggat actggagtga ctggagtgaa 1200

 gaagcaagtg ggatcaccta tgaagataac attgcctcct tttgaagcca 1250

 atggaaaaat cttggattat gaagtgactc tcacaagatg gaaatcacat 1300

 ttacaaaatt acacagttaa tgccacaaaa ctgacagtaa atctcacaaa 1350

 tgatcgctat ctagcaaccc taacagtaag aaatcttgtt ggcaaatcag 1400

 atgcagctgt tttaactatc cctgcctgtg actttcaagc tactcaccct 1450

 gtaatggatc ttaaagcatt ccccaaagat aacatgcttt gggtggaatg 1500

 gactactcca agggaatctg taaagaaata tatacttgag tggtgtgtgt 1550

 tatcagataa agcaccctgt atcacagact ggcaacaaga agatggtacc 1600

 gtgcatcgca cctatttaag agggaactta gcagagagca aatgctattt 1650

 gataacagtt actccagtat atgctgatgg accaggaagc cctgaatcca 1700

 taaaggcata ccttaaacaa gctccacctt ccaaaggacc tactgttcgg 1750

 acaaaaaaag tagggaaaaa cgaagctgtc ttagagtggg accaacttcc 1800

 tgttgatgtt cagaatggat ttatcagaaa ttatactata ttttatagaa 1850

 ccatcattgg aaatgaaact gctgtgaatg tggattcttc ccacacagaa 1900

 tatacattgt cctctttgac tagtgacaca ttgtacatgg tacgaatggc 1950

 agcatacaca gatgaaggtg ggaaggatgg tccagaattc acttttacta 2000

 ccccaaagtt tgctcaagga gaaattgaag ccatagtcgt gcctgtttgc 2050

 ttagcattcc tattgacaac tcttctggga gtgctgttct gctttaataa 2100

 gcgagaccta attaaaaaac acatctggcc taatgttcca gatccttcaa 2150

 agagtcatat tgcccagtgg tcacctcaca ctcctccaag gcacaatttt 2200

 aattcaaaag atcaaatgta ttcagatggc aatttcactg atgtaagtgt 2250

 tgtggaaata gaagcaaatg acaaaaagcc ttttccagaa gatctgaaat 2300

 cattggacct gttcaaaaag gaaaaaatta atactgaagg acacagcagt 2350

 ggtattgggg ggtcttcatg catgtcatct tctaggccaa gcatttctag 2400

 cagtgatgaa aatgaatctt cacaaaacac ttcgagcact gtccagtatt 2450

 ctaccgtggt acacagtggc tacagacacc aagttccgtc agtccaagtc 2500

 ttctcaagat ccgagtctac ccagcccttg ttagattcag aggagcggcc 2550

 agaagatcta caattagtag atcatgtaga tggcggtgat ggtattttgc 2600

 ccaggcaaca gtacttcaaa cagaactgca gtcagcatga atccagtcca 2650

 gatatttcac attttgaaag gtcaaagcaa gtttcatcag tcaatgagga 2700

 agattttgtt agacttaaac agcagatttc agatcatatt tcacaatcct 2750

 gtggatctgg gcaaatgaaa atgtttcagg aagtttctgc agcagatgct 2800

 tttggtccag gtactgaggg acaagtagaa agatttgaaa cagttggcat 2850

 ggaggctgcg actgatgaag gcatgcctaa aagttactta ccacagactg 2900

 tacggcaagg cggctacatg cctcagtgaa ggactagtag ttcctgctac 2950

 aacttcagca gtacctataa agtaaagcta aaatgatttt atctgtgaat 3000

 tcagatttta aaaagtcttc actctctgaa gatgatcatt tgcccttaag 3050

 gacaaaaatg aactgaagtt tcacatgagc tatttccatt ccagaatatc 3100

 tgggattcta ctttaagcac tacataaact gactttatcc tcagaaaaaa 3150

 aaaaaaaaa 3159

<210> 1238
<211> 329
<212> PRT
<213> Homo sapien

<400> 1238
 Met Leu Thr Leu Gln Thr Trp Leu Val Gln Ala Leu Phe Ile Phe
   1               5                  10                  15

 Leu Thr Thr Glu Ser Thr Gly Glu Leu Leu Asp Pro Cys Gly Tyr
                  20                  25                  30

 Ile Ser Pro Glu Ser Pro Val Val Gln Leu His Ser Asn Phe Thr
                  35                  40                  45

 Ala Val Cys Val Leu Lys Glu Lys Cys Met Asp Tyr Phe His Val
                  50                  55                  60

 Asn Ala Asn Tyr Ile Val Trp Lys Thr Asn His Phe Thr Ile Pro
                  65                  70                  75

 Lys Glu Gln Tyr Thr Ile Ile Asn Arg Thr Ala Ser Ser Val Thr
                  80                  85                  90

 Phe Thr Asp Ile Ala Ser Leu Asn Ile Gln Leu Thr Cys Asn Ile
                  95                 100                 105

 Leu Thr Phe Gly Gln Leu Glu Gln Asn Val Tyr Gly Ile Thr Ile
                 110                 115                 120

 Ile Ser Gly Leu Pro Pro Glu Lys Pro Lys Asn Leu Ser Cys Ile
                 125                 130                 135

 Val Asn Glu Gly Lys Lys Met Arg Cys Glu Trp Asp Gly Gly Arg
                 140                 145                 150

 Glu Thr His Leu Glu Thr Asn Phe Thr Leu Lys Ser Glu Trp Ala
                 155                 160                 165

 Thr His Lys Phe Ala Asp Cys Lys Ala Lys Arg Asp Thr Pro Thr
                 170                 175                 180

 Ser Cys Thr Val Asp Tyr Ser Thr Val Tyr Phe Val Asn Ile Glu
                 185                 190                 195

 Val Trp Val Glu Ala Glu Asn Ala Leu Gly Lys Val Thr Ser Asp
                 200                 205                 210

 His Ile Asn Phe Asp Pro Val Tyr Lys Val Lys Pro Asn Pro Pro
                 215                 220                 225

 His Asn Leu Ser Val Ile Asn Ser Glu Glu Leu Ser Ser Ile Leu
                 230                 235                 240

 Lys Leu Thr Trp Thr Asn Pro Ser Ile Lys Ser Val Ile Ile Leu
                 245                 250                 255

 Lys Tyr Asn Ile Gln Tyr Arg Thr Lys Asp Ala Ser Thr Trp Ser
                 260                 265                 270

 Gln Ile Pro Pro Glu Asp Thr Ala Ser Thr Arg Ser Ser Phe Thr
                 275                 280                 285

 Val Gln Asp Leu Lys Pro Phe Thr Glu Tyr Val Phe Arg Ile Arg
                 290                 295                 300

 Cys Met Lys Glu Asp Gly Lys Gly Tyr Trp Ser Asp Trp Ser Glu
                 305                 310                 315

 Glu Ala Ser Gly Ile Thr Tyr Glu Asp Asn Ile Ala Ser Phe
                 320                 325

<210> 1239
<211> 2739
<212> DNA
<213> Homo sapien

<400> 1239
 cgactgcagc ctgggtttta ttcttggcct ggccctgacc gggagctggc 50

 ccctcggctg cttctctggc tcggggggga ctttctctgg ctcagatccg 100

 gacccctgaa ctggacctgg ttgtcgtccc cccgcttctc agccccctct 150

 ggggttcctc tctcctctcc gcccactctt tgctcactgc cccatgtccc 200

 tcggtcagtc ggcctgtctg ttcctctcta tagctcggtc aaggagtgtg 250

 atgactggcg agcagatggc tgccttccat ccatcgtcca cccccaaccc 300

 gctggagagg cccatcaaga tgggctggct gaagaagcag aggtccatcg 350

 tgaagaactg gcagcagagg tactttgtgc tgagggcgca gcagctctac 400

 tactacaagg atgaagagga cacgaagccc cagggctgca tgtatctacc 450

 aggatgtaca atcaaggaga tcgccacaaa cccagaagaa gctgggaagt 500

 ttgtctttga aatcattcca gcctcatggg accagaatcg catgggacag 550

 gactcctatg tcctcatggc cagctctcag gcggagatgg aggagtgggt 600

 taaattcctc aggagagttg ctggcacacc ctgtggagtg tttggccagc 650

 gcttggatga gactgtggcc tatgaacaga aattcggccc ccatctggtg 700

 cccatcctgg tggagaaatg tgcagagttc atcctggagc acggccggaa 750

 tgaagagggc atcttccgtc tgcctgggca ggacaacctg gtgaagcagc 800

 tgagagacgc ttttgatgct ggggagcggc cctcctttga cagagacaca 850

 gatgtgcaca ctgtggcttc cctgttaaag ctctacctcc gagacctccc 900

 agagcccgtg gttccctgga gccagtacga agggttcctg ctctgtgggc 950

 agctcacgaa tgcggatgag gcaaaggctc agcaggagtt gatgaagcag 1000

 ctctccatcc ttcctcgtga caactatagt ctcctgagct acatctgcag 1050

 gttcctacat gaaatacagc tgaactgtgc tgttaacaag atgagtgtgg 1100

 acaacctggc tactgtgatt ggtgtgaatc tcatcaggtc gaaggtcgaa 1150

 gaccctgccg tgatcatgag agggactcct cagatccaaa gagtgatgac 1200

 tatgatgatc agagaccatg aagtcctctt ccccaagtcc aaggatatac 1250

 ccctgtcacc ccctgcccag aaaaatgacc ccaagaaagc tccagtggcc 1300

 cgaagctctg taggctggga tgccactgaa gacctccgaa tttctaggac 1350

 agacagcttc agtagcatga caagcgactc tgatacaacc agccccaccg 1400

 gacagcagcc gagcgatgcg tttccggagg acagcagcaa agtacccagg 1450

 gaaaagccag gagactggaa aatgcaatct cgtaaaagga ctcaaacact 1500

 ccctaaccgg aaatgtttct tgacatcagc ttttcagggt gccaacagca 1550

 gcaaaatgga gatctttaaa aatgaattct ggtcgccttc ctcagaggct 1600

 aaggcagggg aagggcacag gagaacgatg tctcaagact tgcgccaact 1650

 ttctgactcc caacggactt ccacctacga taacgtccct tccctgccag 1700

 ggtcccctgg ggaggaagcc agtgcactct cttcccaagc ctgtgactcc 1750

 aagggagata ctcttgccag tccaaactct gaaactgggc ctggaaaaaa 1800

 gaactctgga gaagaggaaa ttgattcttt gcagaggatg gtccaagagc 1850

 tacgaaagga aatagaaaca cagaagcaaa tgtatgagga acagattaaa 1900

 aaccttgaga aggaaaatta tgacgtttgg gctaaagtgg tgaggctcaa 1950

 tgaagaactg gagaaggaaa agaagaagtc tgcagcccta gagatcagcc 2000

 tccgcaacat ggagcgctcc cgggaggatg ttgagaagag gaacaaggcc 2050

 ttggaagaag aagtcaagga atttgtcaaa tccatgaagg aacccaagac 2100

 cgaggcttaa gggtcccagg agtactgcag ggacagcccc agagaggccc 2150

 aactctggcc cctttctcag tgctatctga tgacggggaa acaaaattat 2200

 tctctgagag ggaaaggaca tttgagggaa acatcaaatt tccccataaa 2250

 taaatgaatg gagtttgcag gaaggtgagg gtgagcagag atgtgtgtgg 2300

 acatctctga ccatccatcg ctgtattcaa atggattgtt ctattccatt 2350

 ctggtctcag gcatgaccac gtccagtgaa gacatttgag gcagcacatc 2400

 tcaggaccca ggcaatagac tggccccaac tcaggctgga ctaaggtgtg 2450

 attaattctt tgttttttgt gtggaacagc tcaccttgtc agacagcctc 2500

 agggcatctc tgagacacag gggcagaaaa tgacattcat cttttgagtc 2550

 ctcatccatg gagtgctgtg tttggggggc tgcatctgct gaagcgagaa 2600

 ccccattctg ccaccccacc aggatgccca ttctccagga cttctccaac 2650

 ttactattag actaaaccag aacaagcaac aaactgtatt tatgcaagca 2700

 aaattgatga gaaaattata ttcaaataaa gcaaaattt 2739

<210> 1240
<211> 638
<212> PRT
<213> Homo sapien

<400> 1240
 Met Ser Leu Gly Gln Ser Ala Cys Leu Phe Leu Ser Ile Ala Arg
   1               5                  10                  15

 Ser Arg Ser Val Met Thr Gly Glu Gln Met Ala Ala Phe His Pro
                  20                  25                  30

 Ser Ser Thr Pro Asn Pro Leu Glu Arg Pro Ile Lys Met Gly Trp
                  35                  40                  45

 Leu Lys Lys Gln Arg Ser Ile Val Lys Asn Trp Gln Gln Arg Tyr
                  50                  55                  60

 Phe Val Leu Arg Ala Gln Gln Leu Tyr Tyr Tyr Lys Asp Glu Glu
                  65                  70                  75

 Asp Thr Lys Pro Gln Gly Cys Met Tyr Leu Pro Gly Cys Thr Ile
                  80                  85                  90

 Lys Glu Ile Ala Thr Asn Pro Glu Glu Ala Gly Lys Phe Val Phe
                  95                 100                 105

 Glu Ile Ile Pro Ala Ser Trp Asp Gln Asn Arg Met Gly Gln Asp
                 110                 115                 120

 Ser Tyr Val Leu Met Ala Ser Ser Gln Ala Glu Met Glu Glu Trp
                 125                 130                 135

 Val Lys Phe Leu Arg Arg Val Ala Gly Thr Pro Cys Gly Val Phe
                 140                 145                 150

 Gly Gln Arg Leu Asp Glu Thr Val Ala Tyr Glu Gln Lys Phe Gly
                 155                 160                 165

 Pro His Leu Val Pro Ile Leu Val Glu Lys Cys Ala Glu Phe Ile
                 170                 175                 180

 Leu Glu His Gly Arg Asn Glu Glu Gly Ile Phe Arg Leu Pro Gly
                 185                 190                 195

 Gln Asp Asn Leu Val Lys Gln Leu Arg Asp Ala Phe Asp Ala Gly
                 200                 205                 210

 Glu Arg Pro Ser Phe Asp Arg Asp Thr Asp Val His Thr Val Ala
                 215                 220                 225

 Ser Leu Leu Lys Leu Tyr Leu Arg Asp Leu Pro Glu Pro Val Val
                 230                 235                 240

 Pro Trp Ser Gln Tyr Glu Gly Phe Leu Leu Cys Gly Gln Leu Thr
                 245                 250                 255

 Asn Ala Asp Glu Ala Lys Ala Gln Gln Glu Leu Met Lys Gln Leu
                 260                 265                 270

 Ser Ile Leu Pro Arg Asp Asn Tyr Ser Leu Leu Ser Tyr Ile Cys
                 275                 280                 285

 Arg Phe Leu His Glu Ile Gln Leu Asn Cys Ala Val Asn Lys Met
                 290                 295                 300

 Ser Val Asp Asn Leu Ala Thr Val Ile Gly Val Asn Leu Ile Arg
                 305                 310                 315

 Ser Lys Val Glu Asp Pro Ala Val Ile Met Arg Gly Thr Pro Gln
                 320                 325                 330

 Ile Gln Arg Val Met Thr Met Met Ile Arg Asp His Glu Val Leu
                 335                 340                 345

 Phe Pro Lys Ser Lys Asp Ile Pro Leu Ser Pro Pro Ala Gln Lys
                 350                 355                 360

 Asn Asp Pro Lys Lys Ala Pro Val Ala Arg Ser Ser Val Gly Trp
                 365                 370                 375

 Asp Ala Thr Glu Asp Leu Arg Ile Ser Arg Thr Asp Ser Phe Ser
                 380                 385                 390

 Ser Met Thr Ser Asp Ser Asp Thr Thr Ser Pro Thr Gly Gln Gln
                 395                 400                 405

 Pro Ser Asp Ala Phe Pro Glu Asp Ser Ser Lys Val Pro Arg Glu
                 410                 415                 420

 Lys Pro Gly Asp Trp Lys Met Gln Ser Arg Lys Arg Thr Gln Thr
                 425                 430                 435

 Leu Pro Asn Arg Lys Cys Phe Leu Thr Ser Ala Phe Gln Gly Ala
                 440                 445                 450

 Asn Ser Ser Lys Met Glu Ile Phe Lys Asn Glu Phe Trp Ser Pro
                 455                 460                 465

 Ser Ser Glu Ala Lys Ala Gly Glu Gly His Arg Arg Thr Met Ser
                 470                 475                 480

 Gln Asp Leu Arg Gln Leu Ser Asp Ser Gln Arg Thr Ser Thr Tyr
                 485                 490                 495

 Asp Asn Val Pro Ser Leu Pro Gly Ser Pro Gly Glu Glu Ala Ser
                 500                 505                 510

 Ala Leu Ser Ser Gln Ala Cys Asp Ser Lys Gly Asp Thr Leu Ala
                 515                 520                 525

 Ser Pro Asn Ser Glu Thr Gly Pro Gly Lys Lys Asn Ser Gly Glu
                 530                 535                 540

 Glu Glu Ile Asp Ser Leu Gln Arg Met Val Gln Glu Leu Arg Lys
                 545                 550                 555

 Glu Ile Glu Thr Gln Lys Gln Met Tyr Glu Glu Gln Ile Lys Asn
                 560                 565                 570

 Leu Glu Lys Glu Asn Tyr Asp Val Trp Ala Lys Val Val Arg Leu
                 575                 580                 585

 Asn Glu Glu Leu Glu Lys Glu Lys Lys Lys Ser Ala Ala Leu Glu
                 590                 595                 600

 Ile Ser Leu Arg Asn Met Glu Arg Ser Arg Glu Asp Val Glu Lys
                 605                 610                 615

 Arg Asn Lys Ala Leu Glu Glu Glu Val Lys Glu Phe Val Lys Ser
                 620                 625                 630

 Met Lys Glu Pro Lys Thr Glu Ala
                 635

<210> 1241
<211> 3331
<212> DNA
<213> Homo sapien

<400> 1241
 cagagggcac cgcccaggcc tcggaaggtg tcagggagaa ctttccgtgg 50

 tttcagcgtc gtcgcctgga gcggcggttt agagagccga gcctgatggg 100

 cgccaaggcc ggctggctgc ttggagcgct gcctcgaagg gactgcgtaa 150

 ggaagctaat ccggagaacc caggccagag cctgaaatat ggcgacctgc 200

 atcggggaga agatcgagga ttttaaagtt ggaaatctgc ttggtaaagg 250

 atcatttgct ggtgtctaca gagctgagtc cattcacagt ggtttggaag 300

 ttgcaatcaa aatgatagat aagaaagcca tgtacaaagc aggaatggta 350

 cagagagtcc aaaatgaggt gaaaatacat tgccaattga aacatccttc 400

 tatcttggag ctttataact attttgaaga tagcaattat gtgtatctgg 450

 tattagaaat gtgccataat ggagaaatga acaggtatct aaagaataga 500

 gtgaaaccct tctcagaaaa tgaagctcga cacttcatgc accagatcat 550

 cacagggatg ttgtatcttc attctcatgg tatactacac cgggacctca 600

 cactttctaa cctcctactg actcgtaata tgaacatcaa gattgctgat 650

 tttgggctgg caactcaact gaaaatgcca catgaaaagc actatacatt 700

 atgtggaact cctaactaca tttcaccaga aattgccact cgaagtgcac 750

 atggccttga atctgatgtt tggtccctgg gctgtatgtt ttatacatta 800

 cttatcggga gaccaccctt cgacactgac acagtcaaga acacattaaa 850

 taaagtagta ttggcagatt atgaaatgcc aacttttttg tcaatagagg 900

 ccaaggacct tattcaccag ttacttcgta gaaatccagc agatcgttta 950

 agtctgtctt cagtattgga ccatcctttt atgtcccgaa attcttcaac 1000

 aaaaagtaaa gatttaggaa ctgtggaaga ctcaattgat agtgggcatg 1050

 ccacaatttc tactgcaatt acagcttctt ccagtaccag tataagtggt 1100

 agtttatttg acaaaagaag acttttgatt ggtcagccac tcccaaataa 1150

 aatgactgta tttccaaaga ataaaagttc aactgatttt tcttcttcag 1200

 gagatggaaa cagtttttat actcagtggg gaaatcaaga aaccagtaat 1250

 agtggaaggg gaagagtaat tcaagatgca gaagaaaggc cacattctcg 1300

 ataccttcgt agagcttatt cctctgatag atctggcact tctaatagac 1350

 agtctcaagc aaaaacatat acaatggaac gatgtcactc agcagaaatg 1400

 ctttcagtgt ccaaaagatc aggaggaggt gaaaatgaag agaggtactc 1450

 acccacagac aacaatgcca acatttttaa cttctttaaa gaaaagacat 1500

 ccagtagttc tggatctttt gaaagacctg ataacaatca agcactctcc 1550

 aatcatcttt gtccaggaaa aactcctttt ccatttgcag acccgacacc 1600

 tcagactgaa accgtacaac agtggtttgg gaatctgcaa ataaatgctc 1650

 atttaagaaa aactactgaa tatgacagca tcagcccaaa ccgggacttc 1700

 cagggccatc cagatttgca gaaggacaca tcaaaaaatg cctggactga 1750

 tacaaaagtc aaaaagaact ctgatgcttc tgataatgca cattctgtaa 1800

 aacagcaaaa taccatgaaa tatatgactg cacttcacag taaacctgag 1850

 ataatccaac aagaatgtgt ttttggctca gatcctcttt ctgaacagag 1900

 caagactagg ggtatggagc caccatgggg ttatcagaat cgtacattaa 1950

 gaagcattac atctccgttg gttgctcaca ggttaaaacc aatcagacag 2000

 aaaaccaaaa aggctgtggt gagcatactt gattcagagg aggtgtgtgt 2050

 ggagcttgta aaggagtatg catctcaaga atatgtgaaa gaagttcttc 2100

 agatatctag tgatggaaat acgatcacta tttattatcc aaatggtggt 2150

 agaggttttc ctcttgctga tagaccaccc tcacctactg acaacatcag 2200

 taggtacagc tttgacaatt taccagaaaa atactggcga aaatatcaat 2250

 atgcttccag gtttgtacag cttctaagat ctaaatctcc caaaatcact 2300

 tattttacaa gatatgctaa atgcattttg atggagaatt ctcctggtgc 2350

 tgattttgag gtttggtttt atgatggggt aaaaatacac aaaacagaag 2400

 atttcattca ggtgattgaa aagacaggga agtcttacac tttaaaaagt 2450

 gaaagtgaag ttaatagctt gaaagaggag ataaaaatgt atatggacca 2500

 tgctaatgag ggtcatcgta tttgtttagc actggaatcc ataatttcag 2550

 aagaggaaag gaaaactagg agtgctccct ttttcccaat aatcatagga 2600

 agaaaacctg gtagtactag ttcacctaag gccttatcac ctcctccttc 2650

 tgtggattca aattacccaa cgagagatag agcatctttc aacagaatgg 2700

 tcatgcatag tgatgcttct ccaacacagg caccaatcct taatccctct 2750

 atggttacaa atgaaggact tggtcttaca actacagctt ctggaacaga 2800

 catctcttct aatagtctaa aagattgtct tcctaaatca gcacaacttt 2850

 tgaaatctgt ttttgtgaaa aatgttggtt gggctacaca gttaactagt 2900

 ggagctgtgt gggttcagtt taatgatggg tcccagttgg ttgtgcaggc 2950

 aggagtgtct tctatcagtt atacctcacc aaatggtcaa acaactaggt 3000

 atggagaaaa tgaaaaatta ccagactaca tcaaacagaa attacagtgt 3050

 ctgtcttcca tccttttgat gttttctaat ccgactccta attttcattg 3100

 attaaaactc ctttcagaca tataagttta ataaataact tttttgttga 3150

 ctttcaagta aagtgatttt ttttaattta acataaagtc ttcagaaagc 3200

 ctttctatga aagaatttta acctataatg taaaccatgt atctgagata 3250

 acaaagcaga atgaaacttg agtcacttac taaatatagt ggatataaaa 3300

 tagaacacct gactttgctc ttagaccata a 3331

<210> 1242
<211> 970
<212> PRT
<213> Homo sapien

<400> 1242
 Met Ala Thr Cys Ile Gly Glu Lys Ile Glu Asp Phe Lys Val Gly
   1               5                  10                  15

 Asn Leu Leu Gly Lys Gly Ser Phe Ala Gly Val Tyr Arg Ala Glu
                  20                  25                  30

 Ser Ile His Ser Gly Leu Glu Val Ala Ile Lys Met Ile Asp Lys
                  35                  40                  45

 Lys Ala Met Tyr Lys Ala Gly Met Val Gln Arg Val Gln Asn Glu
                  50                  55                  60

 Val Lys Ile His Cys Gln Leu Lys His Pro Ser Ile Leu Glu Leu
                  65                  70                  75

 Tyr Asn Tyr Phe Glu Asp Ser Asn Tyr Val Tyr Leu Val Leu Glu
                  80                  85                  90

 Met Cys His Asn Gly Glu Met Asn Arg Tyr Leu Lys Asn Arg Val
                  95                 100                 105

 Lys Pro Phe Ser Glu Asn Glu Ala Arg His Phe Met His Gln Ile
                 110                 115                 120

 Ile Thr Gly Met Leu Tyr Leu His Ser His Gly Ile Leu His Arg
                 125                 130                 135

 Asp Leu Thr Leu Ser Asn Leu Leu Leu Thr Arg Asn Met Asn Ile
                 140                 145                 150

 Lys Ile Ala Asp Phe Gly Leu Ala Thr Gln Leu Lys Met Pro His
                 155                 160                 165

 Glu Lys His Tyr Thr Leu Cys Gly Thr Pro Asn Tyr Ile Ser Pro
                 170                 175                 180

 Glu Ile Ala Thr Arg Ser Ala His Gly Leu Glu Ser Asp Val Trp
                 185                 190                 195

 Ser Leu Gly Cys Met Phe Tyr Thr Leu Leu Ile Gly Arg Pro Pro
                 200                 205                 210

 Phe Asp Thr Asp Thr Val Lys Asn Thr Leu Asn Lys Val Val Leu
                 215                 220                 225

 Ala Asp Tyr Glu Met Pro Thr Phe Leu Ser Ile Glu Ala Lys Asp
                 230                 235                 240

 Leu Ile His Gln Leu Leu Arg Arg Asn Pro Ala Asp Arg Leu Ser
                 245                 250                 255

 Leu Ser Ser Val Leu Asp His Pro Phe Met Ser Arg Asn Ser Ser
                 260                 265                 270

 Thr Lys Ser Lys Asp Leu Gly Thr Val Glu Asp Ser Ile Asp Ser
                 275                 280                 285

 Gly His Ala Thr Ile Ser Thr Ala Ile Thr Ala Ser Ser Ser Thr
                 290                 295                 300

 Ser Ile Ser Gly Ser Leu Phe Asp Lys Arg Arg Leu Leu Ile Gly
                 305                 310                 315

 Gln Pro Leu Pro Asn Lys Met Thr Val Phe Pro Lys Asn Lys Ser
                 320                 325                 330

 Ser Thr Asp Phe Ser Ser Ser Gly Asp Gly Asn Ser Phe Tyr Thr
                 335                 340                 345

 Gln Trp Gly Asn Gln Glu Thr Ser Asn Ser Gly Arg Gly Arg Val
                 350                 355                 360

 Ile Gln Asp Ala Glu Glu Arg Pro His Ser Arg Tyr Leu Arg Arg
                 365                 370                 375

 Ala Tyr Ser Ser Asp Arg Ser Gly Thr Ser Asn Arg Gln Ser Gln
                 380                 385                 390

 Ala Lys Thr Tyr Thr Met Glu Arg Cys His Ser Ala Glu Met Leu
                 395                 400                 405

 Ser Val Ser Lys Arg Ser Gly Gly Gly Glu Asn Glu Glu Arg Tyr
                 410                 415                 420

 Ser Pro Thr Asp Asn Asn Ala Asn Ile Phe Asn Phe Phe Lys Glu
                 425                 430                 435

 Lys Thr Ser Ser Ser Ser Gly Ser Phe Glu Arg Pro Asp Asn Asn
                 440                 445                 450

 Gln Ala Leu Ser Asn His Leu Cys Pro Gly Lys Thr Pro Phe Pro
                 455                 460                 465

 Phe Ala Asp Pro Thr Pro Gln Thr Glu Thr Val Gln Gln Trp Phe
                 470                 475                 480

 Gly Asn Leu Gln Ile Asn Ala His Leu Arg Lys Thr Thr Glu Tyr
                 485                 490                 495

 Asp Ser Ile Ser Pro Asn Arg Asp Phe Gln Gly His Pro Asp Leu
                 500                 505                 510

 Gln Lys Asp Thr Ser Lys Asn Ala Trp Thr Asp Thr Lys Val Lys
                 515                 520                 525

 Lys Asn Ser Asp Ala Ser Asp Asn Ala His Ser Val Lys Gln Gln
                 530                 535                 540

 Asn Thr Met Lys Tyr Met Thr Ala Leu His Ser Lys Pro Glu Ile
                 545                 550                 555

 Ile Gln Gln Glu Cys Val Phe Gly Ser Asp Pro Leu Ser Glu Gln
                 560                 565                 570

 Ser Lys Thr Arg Gly Met Glu Pro Pro Trp Gly Tyr Gln Asn Arg
                 575                 580                 585

 Thr Leu Arg Ser Ile Thr Ser Pro Leu Val Ala His Arg Leu Lys
                 590                 595                 600

 Pro Ile Arg Gln Lys Thr Lys Lys Ala Val Val Ser Ile Leu Asp
                 605                 610                 615

 Ser Glu Glu Val Cys Val Glu Leu Val Lys Glu Tyr Ala Ser Gln
                 620                 625                 630

 Glu Tyr Val Lys Glu Val Leu Gln Ile Ser Ser Asp Gly Asn Thr
                 635                 640                 645

 Ile Thr Ile Tyr Tyr Pro Asn Gly Gly Arg Gly Phe Pro Leu Ala
                 650                 655                 660

 Asp Arg Pro Pro Ser Pro Thr Asp Asn Ile Ser Arg Tyr Ser Phe
                 665                 670                 675

 Asp Asn Leu Pro Glu Lys Tyr Trp Arg Lys Tyr Gln Tyr Ala Ser
                 680                 685                 690

 Arg Phe Val Gln Leu Leu Arg Ser Lys Ser Pro Lys Ile Thr Tyr
                 695                 700                 705

 Phe Thr Arg Tyr Ala Lys Cys Ile Leu Met Glu Asn Ser Pro Gly
                 710                 715                 720

 Ala Asp Phe Glu Val Trp Phe Tyr Asp Gly Val Lys Ile His Lys
                 725                 730                 735

 Thr Glu Asp Phe Ile Gln Val Ile Glu Lys Thr Gly Lys Ser Tyr
                 740                 745                 750

 Thr Leu Lys Ser Glu Ser Glu Val Asn Ser Leu Lys Glu Glu Ile
                 755                 760                 765

 Lys Met Tyr Met Asp His Ala Asn Glu Gly His Arg Ile Cys Leu
                 770                 775                 780

 Ala Leu Glu Ser Ile Ile Ser Glu Glu Glu Arg Lys Thr Arg Ser
                 785                 790                 795

 Ala Pro Phe Phe Pro Ile Ile Ile Gly Arg Lys Pro Gly Ser Thr
                 800                 805                 810

 Ser Ser Pro Lys Ala Leu Ser Pro Pro Pro Ser Val Asp Ser Asn
                 815                 820                 825

 Tyr Pro Thr Arg Asp Arg Ala Ser Phe Asn Arg Met Val Met His
                 830                 835                 840

 Ser Asp Ala Ser Pro Thr Gln Ala Pro Ile Leu Asn Pro Ser Met
                 845                 850                 855

 Val Thr Asn Glu Gly Leu Gly Leu Thr Thr Thr Ala Ser Gly Thr
                 860                 865                 870

 Asp Ile Ser Ser Asn Ser Leu Lys Asp Cys Leu Pro Lys Ser Ala
                 875                 880                 885

 Gln Leu Leu Lys Ser Val Phe Val Lys Asn Val Gly Trp Ala Thr
                 890                 895                 900

 Gln Leu Thr Ser Gly Ala Val Trp Val Gln Phe Asn Asp Gly Ser
                 905                 910                 915

 Gln Leu Val Val Gln Ala Gly Val Ser Ser Ile Ser Tyr Thr Ser
                 920                 925                 930

 Pro Asn Gly Gln Thr Thr Arg Tyr Gly Glu Asn Glu Lys Leu Pro
                 935                 940                 945

 Asp Tyr Ile Lys Gln Lys Leu Gln Cys Leu Ser Ser Ile Leu Leu
                 950                 955                 960

 Met Phe Ser Asn Pro Thr Pro Asn Phe His
                 965                 970

<210> 1243
<211> 1958
<212> DNA
<213> Homo sapien

<400> 1243
 cggcacagcc tcacacctga acgctgtcct cccgcagacg agaccggcgg 50

 gcactgcaaa gctgggactc gtctttgaag gaaaaaaaat agcgagtaag 100

 aaatccagca ccattcttca ctgacccatc ccgctgcacc tcttgtttcc 150

 caagtttttg aaagctggca actctgacct cggtgtccaa aaatcgacag 200

 ccactgagac cggctttgag aagccgaaga tttggcagtt tccagactga 250

 gcaggacaag gtgaaagcag gttggaggcg ggtccaggac atctgagggc 300

 tgaccctggg ggctcgtgag gctgccaccg ctgctgccgc tacagaccca 350

 gccttgcact ccaaggctgc gcaccgccag ccactatcat gtccactccc 400

 ggggtcaatt cgtccgcctc cttgagcccc gaccggctga acagcccagt 450

 gaccatcccg gcggtgatgt tcatcttcgg ggtggtgggc aacctggtgg 500

 ccatcgtggt gctgtgcaag tcgcgcaagg agcagaagga gacgaccttc 550

 tacacgctgg tatgtgggct ggctgtcacc gacctgttgg gcactttgtt 600

 ggtgagcccg gtgaccatcg ccacgtacat gaagggccaa tggcccgggg 650

 gccagccgct gtgcgagtac agcaccttca ttctgctctt cttcagcctg 700

 tccggcctca gcatcatctg cgccatgagt gtcgagcgct acctggccat 750

 caaccatgcc tatttctaca gccactacgt ggacaagcga ttggcgggcc 800

 tcacgctctt tgcagtctat gcgtccaacg tgctcttttg cgcgctgccc 850

 aacatgggtc tcggtagctc gcggctgcag tacccagaca cctggtgctt 900

 catcgactgg accaccaacg tgacggcgca cgccgcctac tcctacatgt 950

 acgcgggctt cagctccttc ctcattctcg ccaccgtcct ctgcaacgtg 1000

 cttgtgtgcg gcgcgctgct ccgcatgcac cgccagttca tgcgccgcac 1050

 ctcgctgggc accgagcagc accacgcggc cgcggccgcc tcggttgcct 1100

 cccggggcca ccccgctgcc tccccagcct tgccgcgcct cagcgacttt 1150

 cggcgccgcc ggagcttccg ccgcatcgcg ggcgccgaga tccagatggt 1200

 catcttactc attgccacct ccctggtggt gctcatctgc tccatcccgc 1250

 tcgtggtgcg agtattcgtc aaccagttat atcagccaag tttggagcga 1300

 gaagtcagta aaaatccaga tttgcaggcc atccgaattg cttctgtgaa 1350

 ccccatccta gacccctgga tatatatcct cctgagaaag acagtgctca 1400

 gtaaagcaat agagaagatc aaatgcctct tctgccgcat tggcgggtcc 1450

 cgcagggagc gctccggaca gcactgctca gacagtcaaa ggacatcttc 1500

 tgccatgtca ggccactctc gctccttcat ctcccgggag ctgaaggaga 1550

 tcagcagtac atctcagacc ctcctgccag acctctcact gccagacctc 1600

 agtgaaaatg gccttggagg caggaatttg cttccaggtg tgcctggcat 1650

 gggcctggcc caggaagaca ccacctcact gaggactttg cgaatatcag 1700

 agacctcaga ctcttcacag ggtcaggact cagagagtgt cttactggtg 1750

 gatgaggctg gtgggagcgg cagggctggg cctgccccta aggggagctc 1800

 cctgcaagtc acatttccca gtgaaacact gaacttatca gaaaaatgta 1850

 tataataggc aaggaaagaa atacagtact gtttctggac ccttataaaa 1900

 tcctgtgcaa tagacacata catgtcacat ttagctgtgc tcagaagggc 1950

 tatcatca 1958

<210> 1244
<211> 488
<212> PRT
<213> Homo sapien

<400> 1244
 Met Ser Thr Pro Gly Val Asn Ser Ser Ala Ser Leu Ser Pro Asp
   1               5                  10                  15

 Arg Leu Asn Ser Pro Val Thr Ile Pro Ala Val Met Phe Ile Phe
                  20                  25                  30

 Gly Val Val Gly Asn Leu Val Ala Ile Val Val Leu Cys Lys Ser
                  35                  40                  45

 Arg Lys Glu Gln Lys Glu Thr Thr Phe Tyr Thr Leu Val Cys Gly
                  50                  55                  60

 Leu Ala Val Thr Asp Leu Leu Gly Thr Leu Leu Val Ser Pro Val
                  65                  70                  75

 Thr Ile Ala Thr Tyr Met Lys Gly Gln Trp Pro Gly Gly Gln Pro
                  80                  85                  90

 Leu Cys Glu Tyr Ser Thr Phe Ile Leu Leu Phe Phe Ser Leu Ser
                  95                 100                 105

 Gly Leu Ser Ile Ile Cys Ala Met Ser Val Glu Arg Tyr Leu Ala
                 110                 115                 120

 Ile Asn His Ala Tyr Phe Tyr Ser His Tyr Val Asp Lys Arg Leu
                 125                 130                 135

 Ala Gly Leu Thr Leu Phe Ala Val Tyr Ala Ser Asn Val Leu Phe
                 140                 145                 150

 Cys Ala Leu Pro Asn Met Gly Leu Gly Ser Ser Arg Leu Gln Tyr
                 155                 160                 165

 Pro Asp Thr Trp Cys Phe Ile Asp Trp Thr Thr Asn Val Thr Ala
                 170                 175                 180

 His Ala Ala Tyr Ser Tyr Met Tyr Ala Gly Phe Ser Ser Phe Leu
                 185                 190                 195

 Ile Leu Ala Thr Val Leu Cys Asn Val Leu Val Cys Gly Ala Leu
                 200                 205                 210

 Leu Arg Met His Arg Gln Phe Met Arg Arg Thr Ser Leu Gly Thr
                 215                 220                 225

 Glu Gln His His Ala Ala Ala Ala Ala Ser Val Ala Ser Arg Gly
                 230                 235                 240

 His Pro Ala Ala Ser Pro Ala Leu Pro Arg Leu Ser Asp Phe Arg
                 245                 250                 255

 Arg Arg Arg Ser Phe Arg Arg Ile Ala Gly Ala Glu Ile Gln Met
                 260                 265                 270

 Val Ile Leu Leu Ile Ala Thr Ser Leu Val Val Leu Ile Cys Ser
                 275                 280                 285

 Ile Pro Leu Val Val Arg Val Phe Val Asn Gln Leu Tyr Gln Pro
                 290                 295                 300

 Ser Leu Glu Arg Glu Val Ser Lys Asn Pro Asp Leu Gln Ala Ile
                 305                 310                 315

 Arg Ile Ala Ser Val Asn Pro Ile Leu Asp Pro Trp Ile Tyr Ile
                 320                 325                 330

 Leu Leu Arg Lys Thr Val Leu Ser Lys Ala Ile Glu Lys Ile Lys
                 335                 340                 345

 Cys Leu Phe Cys Arg Ile Gly Gly Ser Arg Arg Glu Arg Ser Gly
                 350                 355                 360

 Gln His Cys Ser Asp Ser Gln Arg Thr Ser Ser Ala Met Ser Gly
                 365                 370                 375

 His Ser Arg Ser Phe Ile Ser Arg Glu Leu Lys Glu Ile Ser Ser
                 380                 385                 390

 Thr Ser Gln Thr Leu Leu Pro Asp Leu Ser Leu Pro Asp Leu Ser
                 395                 400                 405

 Glu Asn Gly Leu Gly Gly Arg Asn Leu Leu Pro Gly Val Pro Gly
                 410                 415                 420

 Met Gly Leu Ala Gln Glu Asp Thr Thr Ser Leu Arg Thr Leu Arg
                 425                 430                 435

 Ile Ser Glu Thr Ser Asp Ser Ser Gln Gly Gln Asp Ser Glu Ser
                 440                 445                 450

 Val Leu Leu Val Asp Glu Ala Gly Gly Ser Gly Arg Ala Gly Pro
                 455                 460                 465

 Ala Pro Lys Gly Ser Ser Leu Gln Val Thr Phe Pro Ser Glu Thr
                 470                 475                 480

 Leu Asn Leu Ser Glu Lys Cys Ile
                 485

<210> 1245
<211> 3427
<212> DNA
<213> Homo sapien

<400> 1245
 tggaaaggcg agagcggagc tccaagcccg gcagcccgag aggaagatga 50

 acagccccag gccagagcct ctggcagagt ggaccccgag ccgcccccag 100

 gtagccagga gcggcctcag cggcagccgc aaactccagt agccgcccgt 150

 gctgcccgtg gctggggcgg agggcagcca gagctgggga ccaaggctcc 200

 gcgccacctg cgcgcacagc ctcacacctg aacgctgtcc tcccgcagac 250

 gagaccggcg ggcactgcaa agctgggact cgtctttgaa ggaaaaaaaa 300

 tagcgagtaa gaaatccagc accattcttc actgacccat cccgctgcac 350

 ctcttgtttc ccaagttttt gaaagctggc aactctgacc tcggtgtcca 400

 aaaatcgaca gccactgaga ccggctttga gaagccgaag atttggcagt 450

 ttccagactg agcaggacaa ggtgaaagca ggttggaggc gggtccagga 500

 catctgaggg ctgaccctgg gggctcgtga ggctgccacc gctgctgccg 550

 ctacagaccc agccttgcac tccaaggctg cgcaccgcca gccactatca 600

 tgtccactcc cggggtcaat tcgtccgcct ccttgagccc cgaccggctg 650

 aacagcccag tgaccatccc ggcggtgatg ttcatcttcg gggtggtggg 700

 caacctggtg gccatcgtgg tgctgtgcaa gtcgcgcaag gagcagaagg 750

 agacgacttt ctacacgctg gtatgtgggc tggctgtcac cgacctgttg 800

 ggcactttgt tggtgagccc ggtgaccatc gccacgtaca tgaagggcca 850

 atggcccggg ggccagccgc tgtgcgagta cagcaccttc attctgctct 900

 tcttcagcct gtccggcctc agcatcatct gcgccatgag tgtcgagcgc 950

 tacctggcca tcaaccatgc ctatttctac agccactacg tggacaagcg 1000

 attggcgggc ctcacgctct ttgcagtcta tgcgtccaac gtgctctttt 1050

 gcgcgctgcc caacatgggt ctcggtagct cgcggctgca gtacccagac 1100

 acctggtgct tcatcgactg gaccaccaac gtgacggcgc acgccgccta 1150

 ctcctacatg tacgcgggct tcagctcctt cctcattctc gccaccgtcc 1200

 tctgcaacgt gcttgtgtgc ggcgcgctgc tccgcatgca ccgccagttc 1250

 atgcgccgca cctcgctggg caccgagcag caccacgcgg ccgcggccgc 1300

 ctcggttgcc tcccggggcc accccgctgc ctccccagcc ttgccgcgcc 1350

 tcagcgactt tcggcgccgc cggagcttcc gccgcatcgc gggcgccgag 1400

 atccagatgg tcatcttact cattgccacc tccctggtgg tgctcatctg 1450

 ctccatcccg ctcgtggtgc gagtattcgt caaccagtta tatcagccaa 1500

 gtttggagcg agaagtcagt aaaaatccag atttgcaggc catccgaatt 1550

 gcttctgtga accccatcct agacccctgg atatatatcc tcctgagaaa 1600

 gacagtgctc agtaaagcaa tagagaagat caaatgcctc ttctgccgca 1650

 ttggcgggtc ccgcagggag cgctccggac agcactgctc agacagtcaa 1700

 aggacatctt ctgccatgtc aggccactct cgctccttca tctcccggga 1750

 gctgaaggag atcagcagta catctcagac cctcctgcca gacctctcac 1800

 tgccagacct cagtgaaaat ggccttggag gcaggaattt gcttccaggt 1850

 gtgcctggca tgggcctggc ccaggaagac accacctcac tgaggacttt 1900

 gcgaatatca gagacctcag actcttcaca gggtcaggac tcagagagtg 1950

 tcttactggt ggatgaggct ggtgggagcg gcagggctgg gcctgcccct 2000

 aaggggagct ccctgcaagt cacatttccc agtgaaacac tgaacttatc 2050

 agaaaaatgt atataatagg caaggaaaga aatacagtac tgtttctgga 2100

 cccttataaa atcctgtgca atagacacat acatgtcaca tttagctgtg 2150

 ctcagaaggg ctatcatcat cctacaactc acattagaga acatcctggc 2200

 ttttgagcac ttttcaaaca atcaagttga ctcacgtggg tcctgaggcc 2250

 tgcagcacgt cggatgctac cccactatga cagaggattg tggtcacaac 2300

 ttgatggctg cgaagaccta ccctccgttt ttctactaga taggaggatg 2350

 gtagaagttt ggctgctgtc ataacatcca gagctttgtc gtatttggca 2400

 cacagcagag gcccagatat tagaaaggct ctattccaat aaactatgag 2450

 gactgcctta tggatgattt aagtgtctca ctaaagcatg aaatgtgaat 2500

 ttttattgtt gtacatacga tttaaagtat ttaaagtatt ttcttctctg 2550

 tgagaaggtt tattgttaat acaaggtata ataaaattat cgcaacccct 2600

 ctccttccag tataaccagc tgaagttgca gatgttagat atttttcata 2650

 aacaagttcg agtcaaagtt gaaaattcat agtaagattg atatctataa 2700

 aatagatata aatttttaag agaaagaatt tagtattatc aaagggataa 2750

 agaaaaaaat actatttaag atgtgaaaat tacagtccaa aatactgttc 2800

 tttccaggct atgtataaaa tacatagtga aaattgttta gtgatattac 2850

 atttatttat ccagaaaact gtgatttcag gagaacctaa catgctggtg 2900

 aatattttca actttttccc tcactaattg gtacttttaa aaacataaca 2950

 taaatttttt gaagtcttta ataaataacc cataattgaa gtgtataata 3000

 taaaaaattt taaaaatcta agcagcttat tgtttctctg aaagtgtgtg 3050

 tagttttact ttcctaagga attaccaaga atatccttta aaatttaaaa 3100

 ggatggcaag ttgcatcaga aagctttatt ttgagatgta aaaagattcc 3150

 caaacgtggt tacattagcc attcatgtat gtcagaagtg cagaattggg 3200

 gcacttaatg gtcaccttgt aacagttttg tgtaactccc agtgatgctg 3250

 tacacatatt tgaagggtct ttctcaaaga aatattaagc atgttttgtt 3300

 gctcagtgtt tttgtgaatt gcttggttgt aattaaattc tgagcctgat 3350

 attgatatgg ttttaagaag cagttgtacc aagtgaaatt attttggaga 3400

 ttataataaa tatatacatt caatctg 3427

<210> 1246
<211> 462
<212> PRT
<213> Homo sapien

<400> 1246
 Met Phe Ile Phe Gly Val Val Gly Asn Leu Val Ala Ile Val Val
   1               5                  10                  15

 Leu Cys Lys Ser Arg Lys Glu Gln Lys Glu Thr Thr Phe Tyr Thr
                  20                  25                  30

 Leu Val Cys Gly Leu Ala Val Thr Asp Leu Leu Gly Thr Leu Leu
                  35                  40                  45

 Val Ser Pro Val Thr Ile Ala Thr Tyr Met Lys Gly Gln Trp Pro
                  50                  55                  60

 Gly Gly Gln Pro Leu Cys Glu Tyr Ser Thr Phe Ile Leu Leu Phe
                  65                  70                  75

 Phe Ser Leu Ser Gly Leu Ser Ile Ile Cys Ala Met Ser Val Glu
                  80                  85                  90

 Arg Tyr Leu Ala Ile Asn His Ala Tyr Phe Tyr Ser His Tyr Val
                  95                 100                 105

 Asp Lys Arg Leu Ala Gly Leu Thr Leu Phe Ala Val Tyr Ala Ser
                 110                 115                 120

 Asn Val Leu Phe Cys Ala Leu Pro Asn Met Gly Leu Gly Ser Ser
                 125                 130                 135

 Arg Leu Gln Tyr Pro Asp Thr Trp Cys Phe Ile Asp Trp Thr Thr
                 140                 145                 150

 Asn Val Thr Ala His Ala Ala Tyr Ser Tyr Met Tyr Ala Gly Phe
                 155                 160                 165

 Ser Ser Phe Leu Ile Leu Ala Thr Val Leu Cys Asn Val Leu Val
                 170                 175                 180

 Cys Gly Ala Leu Leu Arg Met His Arg Gln Phe Met Arg Arg Thr
                 185                 190                 195

 Ser Leu Gly Thr Glu Gln His His Ala Ala Ala Ala Ala Ser Val
                 200                 205                 210

 Ala Ser Arg Gly His Pro Ala Ala Ser Pro Ala Leu Pro Arg Leu
                 215                 220                 225

 Ser Asp Phe Arg Arg Arg Arg Ser Phe Arg Arg Ile Ala Gly Ala
                 230                 235                 240

 Glu Ile Gln Met Val Ile Leu Leu Ile Ala Thr Ser Leu Val Val
                 245                 250                 255

 Leu Ile Cys Ser Ile Pro Leu Val Val Arg Val Phe Val Asn Gln
                 260                 265                 270

 Leu Tyr Gln Pro Ser Leu Glu Arg Glu Val Ser Lys Asn Pro Asp
                 275                 280                 285

 Leu Gln Ala Ile Arg Ile Ala Ser Val Asn Pro Ile Leu Asp Pro
                 290                 295                 300

 Trp Ile Tyr Ile Leu Leu Arg Lys Thr Val Leu Ser Lys Ala Ile
                 305                 310                 315

 Glu Lys Ile Lys Cys Leu Phe Cys Arg Ile Gly Gly Ser Arg Arg
                 320                 325                 330

 Glu Arg Ser Gly Gln His Cys Ser Asp Ser Gln Arg Thr Ser Ser
                 335                 340                 345

 Ala Met Ser Gly His Ser Arg Ser Phe Ile Ser Arg Glu Leu Lys
                 350                 355                 360

 Glu Ile Ser Ser Thr Ser Gln Thr Leu Leu Pro Asp Leu Ser Leu
                 365                 370                 375

 Pro Asp Leu Ser Glu Asn Gly Leu Gly Gly Arg Asn Leu Leu Pro
                 380                 385                 390

 Gly Val Pro Gly Met Gly Leu Ala Gln Glu Asp Thr Thr Ser Leu
                 395                 400                 405

 Arg Thr Leu Arg Ile Ser Glu Thr Ser Asp Ser Ser Gln Gly Gln
                 410                 415                 420

 Asp Ser Glu Ser Val Leu Leu Val Asp Glu Ala Gly Gly Ser Gly
                 425                 430                 435

 Arg Ala Gly Pro Ala Pro Lys Gly Ser Ser Leu Gln Val Thr Phe
                 440                 445                 450

 Pro Ser Glu Thr Leu Asn Leu Ser Glu Lys Cys Ile
                 455                 460

<210> 1247
<211> 1067
<212> DNA
<213> Homo sapien

<400> 1247
 gcgtctgcca ggagctacgg ccggaagatg gcggcggccg cagagttgtc 50

 gctactggag aagtccctgg gactgagtaa ggggaataaa tacagtgctc 100

 agggcgagcg acagattcca gttcttcaga caaacaatgg tccaagtcta 150

 acaggattga ctactatagc agctcatcta gtcaagcaag ccaacaaaga 200

 atatttgctg gggagtactg cagaagaaaa agcaatcgtt cagcagtggt 250

 tagaatacag ggtcactcaa gtagatgggc actccagtaa aaatgacatc 300

 cacacactgt tgaaggatct taattcatat cttgaagata aagtctacct 350

 tacagggtat aactttacat tagcagatat actattgtac tatggacttc 400

 atcgctttat agttgacctg acagttcaag aaaaggagaa atatcttaat 450

 gtgtctcgct ggttttgtca cattcagcat tatccaggca tcaggcaaca 500

 tctgtctagt gttgtcttca tcaagaacag actatatact aattcccact 550

 agaagctgtc catgccatac agaagatcta ttaaaagtgt tttaaatgga 600

 aaatgtactc tagaccacag gactaatgta aattaatata cagtcattca 650

 ttatttgttg aagttgatag aatttttgaa gtgtaaactt gtgtctgaat 700

 gttttatttg ttctttagct gaagttttgc aatttttatg tcaaaattca 750

 attgctatta aacaagttga gatccagtta taaattaacc ttgtttttag 800

 tagatgacat ttatttcaat aaaagttgca aatcgggctt aatcttaaaa 850

 ttggtggtca tttcaatggt tgacatattt ggctatttat taacctctct 900

 ttcatattct aaaattcatt ttccccttat ggatatttat ggtagtttgt 950

 taagaactga taaattgtgc caaggaagcc aaaagggaag acagatggat 1000

 ttgttttaaa atgtttatgt gagctagtaa atgtgggaaa aaaaaaaaaa 1050

 aaaaaaaaaa aaaaaaa 1067

<210> 1248
<211> 174
<212> PRT
<213> Homo sapien

<400> 1248
 Met Ala Ala Ala Ala Glu Leu Ser Leu Leu Glu Lys Ser Leu Gly
   1               5                  10                  15

 Leu Ser Lys Gly Asn Lys Tyr Ser Ala Gln Gly Glu Arg Gln Ile
                  20                  25                  30

 Pro Val Leu Gln Thr Asn Asn Gly Pro Ser Leu Thr Gly Leu Thr
                  35                  40                  45

 Thr Ile Ala Ala His Leu Val Lys Gln Ala Asn Lys Glu Tyr Leu
                  50                  55                  60

 Leu Gly Ser Thr Ala Glu Glu Lys Ala Ile Val Gln Gln Trp Leu
                  65                  70                  75

 Glu Tyr Arg Val Thr Gln Val Asp Gly His Ser Ser Lys Asn Asp
                  80                  85                  90

 Ile His Thr Leu Leu Lys Asp Leu Asn Ser Tyr Leu Glu Asp Lys
                  95                 100                 105

 Val Tyr Leu Thr Gly Tyr Asn Phe Thr Leu Ala Asp Ile Leu Leu
                 110                 115                 120

 Tyr Tyr Gly Leu His Arg Phe Ile Val Asp Leu Thr Val Gln Glu
                 125                 130                 135

 Lys Glu Lys Tyr Leu Asn Val Ser Arg Trp Phe Cys His Ile Gln
                 140                 145                 150

 His Tyr Pro Gly Ile Arg Gln His Leu Ser Ser Val Val Phe Ile
                 155                 160                 165

 Lys Asn Arg Leu Tyr Thr Asn Ser His
                 170

<210> 1249
<211> 3649
<212> DNA
<213> Homo sapien

<400> 1249
 agtcccagcc caagggtagc tggaggcgcg caggccggct ccgctccggc 50

 cccggacgat gcggcgcgcc caggatgctg ccgtgcctcg tagtgctgct 100

 ggcggcgctc ctcagcctcc gtcttggctc agacgctcat gggacagagc 150

 tgcccagccc tccgtctgtg tggtttgaag cagaattttt ccaccacatc 200

 ctccactgga cacccatccc aaatcagtct gaaagtacct gctatgaagt 250

 ggcgctcctg aggtatggaa tagagtcctg gaactccatc tccaactgta 300

 gccagaccct gtcctatgac cttaccgcag tgaccttgga cctgtaccac 350

 agcaatggct accgggccag agtgcgggct gtggacggca gccggcactc 400

 caactggacc gtcaccaaca cccgcttctc tgtggatgaa gtgactctga 450

 cagttggcag tgtgaaccta gagatccaca atggcttcat cctcgggaag 500

 attcagctac ccaggcccaa gatggccccc gcaaatgaca catatgaaag 550

 catcttcagt cacttccgag agtatgagat tgccattcgc aaggtgccgg 600

 gaaacttcac gttcacacac aagaaagtaa aacatgaaaa cttcagcctc 650

 ctaacctctg gagaagtggg agagttctgt gtccaggtga aaccatctgt 700

 cgcttcccga agtaacaagg ggatgtggtc taaagaggag tgcatctccc 750

 tcaccaggca gtatttcacc gtgaccaacg tcatcatctt ctttgccttt 800

 gtcctgctgc tctccggagc cctcgcctac tgcctggccc tccagctgta 850

 tgtgcggcgc cgaaagaagc tacccagtgt cctgctcttc aagaagccca 900

 gccccttcat cttcatcagc cagcgtccct ccccagagac ccaagacacc 950

 atccacccgc ttgatgagga ggcctttttg aaggtgtccc cagagctgaa 1000

 gaacttggac ctgcacggca gcacagacag tggctttggc agcaccaagc 1050

 catccctgca gactgaagag ccccagttcc tcctccctga ccctcacccc 1100

 caggctgaca gaacgctggg aaacggggag ccccctgtgc tgggggacag 1150

 ctgcagtagt ggcagcagca atagcacaga cagcgggatc tgcctgcagg 1200

 agcccagcct gagccccagc acagggccca cctgggagca acaggtgggg 1250

 agcaacagca ggggccagga tgacagtggc attgacttag ttcaaaactc 1300

 tgagggccgg gctggggaca cacagggtgg ctcggccttg ggccaccaca 1350

 gtcccccgga gcctgaggtg cctggggaag aagacccagc tgctgtggca 1400

 ttccagggtt acctgaggca gaccagatgt gctgaagaga aggcaaccaa 1450

 gacaggctgc ctggaggaag aatcgccctt gacagatggc cttggcccca 1500

 aattcgggag atgcctggtt gatgaggcag gcttgcatcc accagccctg 1550

 gccaagggct atttgaaaca ggatcctcta gaaatgactc tggcttcctc 1600

 aggggcccca acgggacagt ggaaccagcc cactgaggaa tggtcactcc 1650

 tggccttgag cagctgcagt gacctgggaa tatctgactg gagctttgcc 1700

 catgaccttg cccctctagg ctgtgtggca gccccaggtg gtctcctggg 1750

 cagctttaac tcagacctgg tcaccctgcc cctcatctct agcctgcagt 1800

 caagtgagtg actcgggctg agaggctgct tttgatttta gccatgcctg 1850

 ctcctctgcc tggaccagga ggagggcccc tggggcagaa gttaggcacg 1900

 aggcagtctg ggcacttttc tgcaagtcca ctggggctgg ccccagccag 1950

 gccctgcagg gctggtcagg gtgtctgggg caggaggagg ccaactcact 2000

 gaactagtgc agggtatgtg ggtggcactg acctgttctg ttgactgggg 2050

 ccctgcagac tctggcagag ctgagaaggg cagggacctt ctccctccta 2100

 ggaactcttt cctgtatcat aaaggattat ttgctcaggg gaaccatggg 2150

 gctttctgga gttgtggtga ggccaccagg ctgaagtcag ctcagaccca 2200

 gacctccctg cttaggccac tcgagcatca gagcttccag caggaggaag 2250

 ggctgtagga atggaagctt cagggccttg ctgctggggt catttttagg 2300

 ggaaaaagga ggatatgatg gtcacatggg gaacctcccc tcatcgggcc 2350

 tctggggcag gaagcttgtc actggaagat cttaaggtat atattttctg 2400

 gacactcaaa cacatcataa tggattcact gaggggagac aaagggagcc 2450

 gagaccctgg atggggcttc cagctcagaa cccatccctc tggtgggtac 2500

 ctctggcacc catctgcaaa tatctccctc tctccaacaa atggagtagc 2550

 atccccctgg ggcacttgct gaggccaagc cactcacatc ctcactttgc 2600

 tgccccacca tcttgctgac aacttccaga gaagccatgg ttttttgtat 2650

 tggtcataac tcagcccttt gggcggcctc tgggcttggg caccagctca 2700

 tgccagcccc agagggtcag ggttggaggc ctgtgcttgt gtttgctgct 2750

 aatgtccagc tacagaccca gaggataagc cactgggcac tgggctgggg 2800

 tccctgcctt gttggtgttc agctgtgtga ttttggacta gccacttgtc 2850

 agagggcctc aatctcccat ctgtgaaata aggactccac ctttagggga 2900

 ccctccatgt ttgctgggta ttagccaagc tggtcctggg agaatgcaga 2950

 tactgtccgt ggactaccaa gctggcttgt ttcttatgcc agaggctaac 3000

 agatccaatg ggagtccatg gtgtcatgcc aagacagtat cagacacagc 3050

 cccagaaggg ggcattatgg gccctgcctc cccataggcc atttggactc 3100

 tgccttcaaa caaaggcagt tcagtccaca ggcatggaag ctgtgagggg 3150

 acaggcctgt gcgtgccatc cagagtcatc tcagccctgc ctttctctgg 3200

 agcattctga aaacagatat tctggcccag ggaatccagc catgaccccc 3250

 acccctctgc caaagtactc ttaggtgcca gtctggtaac tgaactccct 3300

 ctggaggcag gcttgaggga ggattcctca gggttccctt gaaagcttta 3350

 tttatttatt ttgttcattt atttattgga gaggcagcat tgcacagtga 3400

 aagaattctg gatatctcag gagccccgaa attctagctc tgactttgct 3450

 gtttccagtg gtatgacctt ggagaagtca cttatcctct tggagcctca 3500

 gtttcctcat ctgcagaata atgactgact tgtctaattc gtagggatgt 3550

 gaggttctgc tgaggaaatg ggtatgaatg tgccttgaac acaaagctct 3600

 gtcaataagt gatacatgtt ttttattcca ataaattgtc aagaccaca 3649

<210> 1250
<211> 578
<212> PRT
<213> Homo sapien

<400> 1250
 Met Leu Pro Cys Leu Val Val Leu Leu Ala Ala Leu Leu Ser Leu
   1               5                  10                  15

 Arg Leu Gly Ser Asp Ala His Gly Thr Glu Leu Pro Ser Pro Pro
                  20                  25                  30

 Ser Val Trp Phe Glu Ala Glu Phe Phe His His Ile Leu His Trp
                  35                  40                  45

 Thr Pro Ile Pro Asn Gln Ser Glu Ser Thr Cys Tyr Glu Val Ala
                  50                  55                  60

 Leu Leu Arg Tyr Gly Ile Glu Ser Trp Asn Ser Ile Ser Asn Cys
                  65                  70                  75

 Ser Gln Thr Leu Ser Tyr Asp Leu Thr Ala Val Thr Leu Asp Leu
                  80                  85                  90

 Tyr His Ser Asn Gly Tyr Arg Ala Arg Val Arg Ala Val Asp Gly
                  95                 100                 105

 Ser Arg His Ser Asn Trp Thr Val Thr Asn Thr Arg Phe Ser Val
                 110                 115                 120

 Asp Glu Val Thr Leu Thr Val Gly Ser Val Asn Leu Glu Ile His
                 125                 130                 135

 Asn Gly Phe Ile Leu Gly Lys Ile Gln Leu Pro Arg Pro Lys Met
                 140                 145                 150

 Ala Pro Ala Asn Asp Thr Tyr Glu Ser Ile Phe Ser His Phe Arg
                 155                 160                 165

 Glu Tyr Glu Ile Ala Ile Arg Lys Val Pro Gly Asn Phe Thr Phe
                 170                 175                 180

 Thr His Lys Lys Val Lys His Glu Asn Phe Ser Leu Leu Thr Ser
                 185                 190                 195

 Gly Glu Val Gly Glu Phe Cys Val Gln Val Lys Pro Ser Val Ala
                 200                 205                 210

 Ser Arg Ser Asn Lys Gly Met Trp Ser Lys Glu Glu Cys Ile Ser
                 215                 220                 225

 Leu Thr Arg Gln Tyr Phe Thr Val Thr Asn Val Ile Ile Phe Phe
                 230                 235                 240

 Ala Phe Val Leu Leu Leu Ser Gly Ala Leu Ala Tyr Cys Leu Ala
                 245                 250                 255

 Leu Gln Leu Tyr Val Arg Arg Arg Lys Lys Leu Pro Ser Val Leu
                 260                 265                 270

 Leu Phe Lys Lys Pro Ser Pro Phe Ile Phe Ile Ser Gln Arg Pro
                 275                 280                 285

 Ser Pro Glu Thr Gln Asp Thr Ile His Pro Leu Asp Glu Glu Ala
                 290                 295                 300

 Phe Leu Lys Val Ser Pro Glu Leu Lys Asn Leu Asp Leu His Gly
                 305                 310                 315

 Ser Thr Asp Ser Gly Phe Gly Ser Thr Lys Pro Ser Leu Gln Thr
                 320                 325                 330

 Glu Glu Pro Gln Phe Leu Leu Pro Asp Pro His Pro Gln Ala Asp
                 335                 340                 345

 Arg Thr Leu Gly Asn Gly Glu Pro Pro Val Leu Gly Asp Ser Cys
                 350                 355                 360

 Ser Ser Gly Ser Ser Asn Ser Thr Asp Ser Gly Ile Cys Leu Gln
                 365                 370                 375

 Glu Pro Ser Leu Ser Pro Ser Thr Gly Pro Thr Trp Glu Gln Gln
                 380                 385                 390

 Val Gly Ser Asn Ser Arg Gly Gln Asp Asp Ser Gly Ile Asp Leu
                 395                 400                 405

 Val Gln Asn Ser Glu Gly Arg Ala Gly Asp Thr Gln Gly Gly Ser
                 410                 415                 420

 Ala Leu Gly His His Ser Pro Pro Glu Pro Glu Val Pro Gly Glu
                 425                 430                 435

 Glu Asp Pro Ala Ala Val Ala Phe Gln Gly Tyr Leu Arg Gln Thr
                 440                 445                 450

 Arg Cys Ala Glu Glu Lys Ala Thr Lys Thr Gly Cys Leu Glu Glu
                 455                 460                 465

 Glu Ser Pro Leu Thr Asp Gly Leu Gly Pro Lys Phe Gly Arg Cys
                 470                 475                 480

 Leu Val Asp Glu Ala Gly Leu His Pro Pro Ala Leu Ala Lys Gly
                 485                 490                 495

 Tyr Leu Lys Gln Asp Pro Leu Glu Met Thr Leu Ala Ser Ser Gly
                 500                 505                 510

 Ala Pro Thr Gly Gln Trp Asn Gln Pro Thr Glu Glu Trp Ser Leu
                 515                 520                 525

 Leu Ala Leu Ser Ser Cys Ser Asp Leu Gly Ile Ser Asp Trp Ser
                 530                 535                 540

 Phe Ala His Asp Leu Ala Pro Leu Gly Cys Val Ala Ala Pro Gly
                 545                 550                 555

 Gly Leu Leu Gly Ser Phe Asn Ser Asp Leu Val Thr Leu Pro Leu
                 560                 565                 570

 Ile Ser Ser Leu Gln Ser Ser Glu
                 575

<210> 1251
<211> 1824
<212> DNA
<213> Homo sapien

<400> 1251
 cagctctctg tcagaatggc caccatggta ccatccgtgt tgtggcccag 50

 ggcctgctgg actctgctgg tctgctgtct gctgacccca ggtgtccagg 100

 ggcaggagtt ccttttgcgg gtggagcccc agaaccctgt gctctctgct 150

 ggagggtccc tgtttgtgaa ctgcagtact gattgtccca gctctgagaa 200

 aatcgccttg gagacgtccc tatcaaagga gctggtggcc agtggcatgg 250

 gctgggcagc cttcaatctc agcaacgtga ctggcaacag tcggatcctc 300

 tgctcagtgt actgcaatgg ctcccagata acaggctcct ctaacatcac 350

 cgtgtacggg ctcccggagc gtgtggagct ggcacccctg cctccttggc 400

 agccggtggg ccagaacttc accctgcgct gccaagtgga gggtgggtcg 450

 ccccggacca gcctcacggt ggtgctgctt cgctgggagg aggagctgag 500

 ccggcagccc gcagtggagg agccagcgga ggtcactgcc actgtgctgg 550

 ccagcagaga cgaccacgga gcccctttct catgccgcac agaactggac 600

 atgcagcccc aggggctggg actgttcgtg aacacctcag ccccccgcca 650

 gctccgaacc tttgtcctgc ccgtgacccc cccgcgcctc gtggcccccc 700

 ggttcttgga ggtggaaacg tcgtggccgg tggactgcac cctagacggg 750

 ctttttccag cctcagaggc ccaggtctac ctggcgctgg gggaccagat 800

 gctgaatgcg acagtcatga accacgggga cacgctaacg gccacagcca 850

 cagccacggc gcgcgcggat caggagggtg cccgggagat cgtctgcaac 900

 gtgaccctag ggggcgagag acgggaggcc cgggagaact tgacggtctt 950

 tagcttccta ggacccattg tgaacctcag cgagcccacc gcccatgagg 1000

 ggtccacagt gaccgtgagt tgcatggctg gggctcgagt ccaggtcacg 1050

 ctggacggag ttccggccgc ggccccgggg cagccagctc aacttcagct 1100

 aaatgctacc gagagtgacg acggacgcag cttcttctgc agtgccactc 1150

 tcgaggtgga cggcgagttc ttgcacagga acagtagcgt ccagctgcga 1200

 gtcctgtatg gtcccaaaat tgaccgagcc acatgccccc agcacttgaa 1250

 atggaaagat aaaacgagac acgtcctgca gtgccaagcc aggggcaacc 1300

 cgtaccccga gctgcggtgt ttgaaggaag gctccagccg ggaggtgccg 1350

 gtggggatcc cgttcttcgt caacgtaaca cataatggta cttatcagtg 1400

 ccaagcgtcc agctcacgag gcaaatacac cctggtcgtg gtgatggaca 1450

 ttgaggctgg gagctcccac tttgtccccg tcttcgtggc ggtgttactg 1500

 accctgggcg tggtgactat cgtactggcc ttaatgtacg tcttcaggga 1550

 gcaccaacgg agcggcagtt accatgttag ggaggagagc acctatctgc 1600

 ccctcacgtc tatgcagccg acagaagcaa tgggggaaga accgtccaga 1650

 gctgagtgac gctgggatcc gggatcaaag ttggcggggg cttggctgtg 1700

 ccctcagatt ccgcaccaat aaagccttca aactccctaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaaaaaaaaa aaaaaaaaaa aaaa 1824

<210> 1252
<211> 547
<212> PRT
<213> Homo sapien

<400> 1252
 Met Ala Thr Met Val Pro Ser Val Leu Trp Pro Arg Ala Cys Trp
   1               5                  10                  15

 Thr Leu Leu Val Cys Cys Leu Leu Thr Pro Gly Val Gln Gly Gln
                  20                  25                  30

 Glu Phe Leu Leu Arg Val Glu Pro Gln Asn Pro Val Leu Ser Ala
                  35                  40                  45

 Gly Gly Ser Leu Phe Val Asn Cys Ser Thr Asp Cys Pro Ser Ser
                  50                  55                  60

 Glu Lys Ile Ala Leu Glu Thr Ser Leu Ser Lys Glu Leu Val Ala
                  65                  70                  75

 Ser Gly Met Gly Trp Ala Ala Phe Asn Leu Ser Asn Val Thr Gly
                  80                  85                  90

 Asn Ser Arg Ile Leu Cys Ser Val Tyr Cys Asn Gly Ser Gln Ile
                  95                 100                 105

 Thr Gly Ser Ser Asn Ile Thr Val Tyr Gly Leu Pro Glu Arg Val
                 110                 115                 120

 Glu Leu Ala Pro Leu Pro Pro Trp Gln Pro Val Gly Gln Asn Phe
                 125                 130                 135

 Thr Leu Arg Cys Gln Val Glu Gly Gly Ser Pro Arg Thr Ser Leu
                 140                 145                 150

 Thr Val Val Leu Leu Arg Trp Glu Glu Glu Leu Ser Arg Gln Pro
                 155                 160                 165

 Ala Val Glu Glu Pro Ala Glu Val Thr Ala Thr Val Leu Ala Ser
                 170                 175                 180

 Arg Asp Asp His Gly Ala Pro Phe Ser Cys Arg Thr Glu Leu Asp
                 185                 190                 195

 Met Gln Pro Gln Gly Leu Gly Leu Phe Val Asn Thr Ser Ala Pro
                 200                 205                 210

 Arg Gln Leu Arg Thr Phe Val Leu Pro Val Thr Pro Pro Arg Leu
                 215                 220                 225

 Val Ala Pro Arg Phe Leu Glu Val Glu Thr Ser Trp Pro Val Asp
                 230                 235                 240

 Cys Thr Leu Asp Gly Leu Phe Pro Ala Ser Glu Ala Gln Val Tyr
                 245                 250                 255

 Leu Ala Leu Gly Asp Gln Met Leu Asn Ala Thr Val Met Asn His
                 260                 265                 270

 Gly Asp Thr Leu Thr Ala Thr Ala Thr Ala Thr Ala Arg Ala Asp
                 275                 280                 285

 Gln Glu Gly Ala Arg Glu Ile Val Cys Asn Val Thr Leu Gly Gly
                 290                 295                 300

 Glu Arg Arg Glu Ala Arg Glu Asn Leu Thr Val Phe Ser Phe Leu
                 305                 310                 315

 Gly Pro Ile Val Asn Leu Ser Glu Pro Thr Ala His Glu Gly Ser
                 320                 325                 330

 Thr Val Thr Val Ser Cys Met Ala Gly Ala Arg Val Gln Val Thr
                 335                 340                 345

 Leu Asp Gly Val Pro Ala Ala Ala Pro Gly Gln Pro Ala Gln Leu
                 350                 355                 360

 Gln Leu Asn Ala Thr Glu Ser Asp Asp Gly Arg Ser Phe Phe Cys
                 365                 370                 375

 Ser Ala Thr Leu Glu Val Asp Gly Glu Phe Leu His Arg Asn Ser
                 380                 385                 390

 Ser Val Gln Leu Arg Val Leu Tyr Gly Pro Lys Ile Asp Arg Ala
                 395                 400                 405

 Thr Cys Pro Gln His Leu Lys Trp Lys Asp Lys Thr Arg His Val
                 410                 415                 420

 Leu Gln Cys Gln Ala Arg Gly Asn Pro Tyr Pro Glu Leu Arg Cys
                 425                 430                 435

 Leu Lys Glu Gly Ser Ser Arg Glu Val Pro Val Gly Ile Pro Phe
                 440                 445                 450

 Phe Val Asn Val Thr His Asn Gly Thr Tyr Gln Cys Gln Ala Ser
                 455                 460                 465

 Ser Ser Arg Gly Lys Tyr Thr Leu Val Val Val Met Asp Ile Glu
                 470                 475                 480

 Ala Gly Ser Ser His Phe Val Pro Val Phe Val Ala Val Leu Leu
                 485                 490                 495

 Thr Leu Gly Val Val Thr Ile Val Leu Ala Leu Met Tyr Val Phe
                 500                 505                 510

 Arg Glu His Gln Arg Ser Gly Ser Tyr His Val Arg Glu Glu Ser
                 515                 520                 525

 Thr Tyr Leu Pro Leu Thr Ser Met Gln Pro Thr Glu Ala Met Gly
                 530                 535                 540

 Glu Glu Pro Ser Arg Ala Glu
                 545

<210> 1253
<211> 916
<212> DNA
<213> Homo sapien

<400> 1253
 acttctcgct cgacacagcc agagctggag gtgggtgccc ggcacggagg 50

 ggcctgcgga ccaatggctc tgccctgcac cttagggctc gggatgctgc 100

 tggccctgcc aggggccttg ggctcgggtg gcagcgcgga ggacagcgtg 150

 ggctccagct ctgtcaccgt tgtcctgctg ctgctgctgc tcctactgct 200

 ggccactggc ctagcactgg cctggcgccg cctcagccgt gactcagggg 250

 gctactacca cccggcccgc ctaggtgccg cgctgtgggg ccgcacgcgg 300

 cgcctgctct gggccagccc cccaggtcgc tggctgcagg cccgagctga 350

 gctggggtcc acagacaatg accttgagcg acaggaggat gagcaggaca 400

 cagactatga ccacgtcgcg gatggtggcc tgcaggctga ccctggggaa 450

 ggcgagcagc aatgtggaga ggcgtccagc ccagagcagg tccccgtgcg 500

 ggctgaggaa gccagagaca gtgacacgga gggcgacctg gtcctcggct 550

 ccccaggacc agcgagcgca gggggcagtg ctgaggccct gctgagtgac 600

 ctgcacgcct ttgctggcag cgcagcctgg gatgacagcg ccagggcagc 650

 tgggggccag ggcctccatg tcaccgcact gtagaggccg gtcttggtgt 700

 cccatccctg tcacagccgc tcactccccg tgcctctgct tcccaagatg 750

 ccatggctgg actggacccc cagcccacat gaccatgcct cagactgtca 800

 cccctaccag ttcccaagtc catgtgtacc ccgctcacca cgggaacggc 850

 cccccccaac cacaggcatc aggcaaccat ttgaaataaa actccttcag 900

 cctgtgaaaa aaaaaa 916

<210> 1254
<211> 206
<212> PRT
<213> Homo sapien

<400> 1254
 Met Ala Leu Pro Cys Thr Leu Gly Leu Gly Met Leu Leu Ala Leu
   1               5                  10                  15

 Pro Gly Ala Leu Gly Ser Gly Gly Ser Ala Glu Asp Ser Val Gly
                  20                  25                  30

 Ser Ser Ser Val Thr Val Val Leu Leu Leu Leu Leu Leu Leu Leu
                  35                  40                  45

 Leu Ala Thr Gly Leu Ala Leu Ala Trp Arg Arg Leu Ser Arg Asp
                  50                  55                  60

 Ser Gly Gly Tyr Tyr His Pro Ala Arg Leu Gly Ala Ala Leu Trp
                  65                  70                  75

 Gly Arg Thr Arg Arg Leu Leu Trp Ala Ser Pro Pro Gly Arg Trp
                  80                  85                  90

 Leu Gln Ala Arg Ala Glu Leu Gly Ser Thr Asp Asn Asp Leu Glu
                  95                 100                 105

 Arg Gln Glu Asp Glu Gln Asp Thr Asp Tyr Asp His Val Ala Asp
                 110                 115                 120

 Gly Gly Leu Gln Ala Asp Pro Gly Glu Gly Glu Gln Gln Cys Gly
                 125                 130                 135

 Glu Ala Ser Ser Pro Glu Gln Val Pro Val Arg Ala Glu Glu Ala
                 140                 145                 150

 Arg Asp Ser Asp Thr Glu Gly Asp Leu Val Leu Gly Ser Pro Gly
                 155                 160                 165

 Pro Ala Ser Ala Gly Gly Ser Ala Glu Ala Leu Leu Ser Asp Leu
                 170                 175                 180

 His Ala Phe Ala Gly Ser Ala Ala Trp Asp Asp Ser Ala Arg Ala
                 185                 190                 195

 Ala Gly Gly Gln Gly Leu His Val Thr Ala Leu
                 200                 205

<210> 1255
<211> 1389
<212> DNA
<213> Homo sapien

<400> 1255
 cgcggacttc tgccaagcac cggctcatgt gaggctcgcg gcacagcgtt 50

 ctctgggctc cccagaagcc agcctttcgc tcccggaccc ggcagcccga 100

 gcaggagccg tgggaccggg cgccagcacc ctctgcggcg tgtcatgggc 150

 ccgcgccgcc ggagccgaaa gcccgaggcc ccgaggaggc gcagcccgag 200

 cccgaccccg acccccggcc cctcccggcg gggcccctcc ttaggcgctt 250

 cctcccatca acacagtcgg cggagacaag gttggctaaa ggagatccga 300

 aagcttcaga agagcacaca cctcttgata aggaagctgc ccttcagccg 350

 cctggcaaga gaaatatgtg ttaaattcac tcgtggtgtg gacttcaatt 400

 ggcaagccca ggccctattg gccctacaag aggcagcaga agcatttcta 450

 gttcatctct ttgaggacgc ctatctcctc accttacatg caggccgagt 500

 tactctcttc ccaaaggatg tgcaactggc ccggaggatc cggggccttg 550

 aggagggact cggctgagct cctgcaccca gtgtttctgt cagtctttcc 600

 tgctcagcca ggggggatga taccggggac tctccagagc catgactaga 650

 tccaatggat tctgcgatgc tgtctggact ttgctgtctc tgaacagtat 700

 gtgtgtgttg ctttaaatat ttttcttttt tttgagaagg agaagactgc 750

 atgactttcc tctgtaacag aggtaatata tgagacaatc aacaccgttc 800

 caaaggcctg aaaataattt tcagataaag agactccaag gttgacttta 850

 gtttgtgagt tactcatgtg actatttgag gattttgaaa acatcagatt 900

 tgctgtggta tgggagaaaa ggttatgtac ttattatttt agctctttct 950

 gtaatattta cattttttac catatgtaca tttgtacttt tattttacac 1000

 ataagggaaa aaataagacc actttgagca gttgcctgga aggctgggca 1050

 tttccatcat atagacctct gcccttcaga gtagcctcac cattagtggc 1100

 agcatcatgt aactgagtgg actgtgcttg tcaacggatg tgtagctttt 1150

 cagaaactta attggggatg aatagaaaac ctgtaagctt tgatgttctg 1200

 gttacttcta gtaaattcct gtcaaaatca attcagaaat tctaacttgg 1250

 agaatttaac attttactct tgtaaatcat agaagatgta tcataacagt 1300

 tcagaatttt aaagtacatt ttcgatgctt ttatgggtat ttttgtagtt 1350

 tctttgtaga gagataataa aaatcaaaat atttaatga 1389

<210> 1256
<211> 140
<212> PRT
<213> Homo sapien

<400> 1256
 Met Gly Pro Arg Arg Arg Ser Arg Lys Pro Glu Ala Pro Arg Arg
   1               5                  10                  15

 Arg Ser Pro Ser Pro Thr Pro Thr Pro Gly Pro Ser Arg Arg Gly
                  20                  25                  30

 Pro Ser Leu Gly Ala Ser Ser His Gln His Ser Arg Arg Arg Gln
                  35                  40                  45

 Gly Trp Leu Lys Glu Ile Arg Lys Leu Gln Lys Ser Thr His Leu
                  50                  55                  60

 Leu Ile Arg Lys Leu Pro Phe Ser Arg Leu Ala Arg Glu Ile Cys
                  65                  70                  75

 Val Lys Phe Thr Arg Gly Val Asp Phe Asn Trp Gln Ala Gln Ala
                  80                  85                  90

 Leu Leu Ala Leu Gln Glu Ala Ala Glu Ala Phe Leu Val His Leu
                  95                 100                 105

 Phe Glu Asp Ala Tyr Leu Leu Thr Leu His Ala Gly Arg Val Thr
                 110                 115                 120

 Leu Phe Pro Lys Asp Val Gln Leu Ala Arg Arg Ile Arg Gly Leu
                 125                 130                 135

 Glu Glu Gly Leu Gly
                 140

<210> 1257
<211> 2905
<212> DNA
<213> Homo sapien

<400> 1257
 cggcagccag ctgagagcaa tgggaaatgg ggagtcccag ctgtcctcgg 50

 tgcctgctca gaagctgggt tggtttatcc aggaatacct gaagccctac 100

 gaagaatgtc agacactgat cgacgagatg gtgaacacca tctgtgacgt 150

 ctgcaggaac cccgaacagt tccccctggt gcagggagtg gccataggtg 200

 gctcctatgg acggaaaaca gtcttaagag gcaactccga tggtaccctt 250

 gtccttttct tcagtgactt aaaacaattc caggatcaga agagaagcca 300

 acgtgacatc ctcgataaaa ctggggataa gctgaagttc tgtctgttca 350

 cgaagtggtt gaaaaacaat ttcgagatcc agaagtccct tgatgggtcc 400

 accatccagg tgttcacaaa aaatcagaga atctctttcg aggtgctggc 450

 cgccttcaac gctctgagct taaatgataa tcccagcccc tggatctatc 500

 gagagctcaa aagatccttg gataagacaa atgccagtcc tggtgagttt 550

 gcagtctgct tcactgaact ccagcagaag ttttttgaca accgtcctgg 600

 aaaactaaag gatttgatcc tcttgataaa gcactggcat caacagtgcc 650

 agaaaaaaat caaggattta ccctcgctgt ctccgtatgc cctggagctg 700

 cttacggtgt atgcctggga acaggggtgc agaaaagaca actttgacat 750

 tgctgaaggc gtcagaacgg ttctggagct gatcaaatgc caggagaagc 800

 tgtgtatcta ttggatggtc aactacaact ttgaagatga gaccatcagg 850

 aacatcctgc tgcaccagct ccaatcagcg aggccagtaa tcttggatcc 900

 agttgaccca accaataatg tgagtggaga taaaatatgc tggcaatggc 950

 tgaaaaaaga agctcaaacc tggttgactt ctcccaacct ggataatgag 1000

 ttacctgcac catcttggaa tgtcctgcct gcaccactct tcacgacccc 1050

 aggccacctt ctggataagt tcatcaagga gtttctccag cccaacaaat 1100

 gcttcctaga gcagattgac agtgctgtta acatcatccg tacattcctt 1150

 aaagaaaact gcttccgaca atcaacagcc aagatccaga ttgtccgggg 1200

 aggatcaacc gccaaaggca cagctctgaa gactggctct gatgccgatc 1250

 tcgtcgtgtt ccataactca cttaaaagct acacctccca aaaaaacgag 1300

 cggcacaaaa tcgtcaagga aatccatgaa cagctgaaag ccttttggag 1350

 ggagaaggag gaggagcttg aagtcagctt tgagcctccc aagtggaagg 1400

 ctcccagggt gctgagcttc tctctgaaat ccaaagtcct caacgaaagt 1450

 gtcagctttg atgtgcttcc tgcctttaat gcactgggtc agctgagttc 1500

 tggctccaca cccagccccg aggtttatgc agggctcatt gatctgtata 1550

 aatcctcgga cctcccggga ggagagtttt ctacctgttt cacagtcctg 1600

 cagcgaaact tcattcgctc ccggcccacc aaactaaagg atttaattcg 1650

 cctggtgaag cactggtaca aagagtgtga aaggaaactg aagccaaagg 1700

 ggtctttgcc cccaaagtat gccttggagc tgctcaccat ctatgcctgg 1750

 gagcagggga gtggagtgcc ggattttgac actgcagaag gtttccggac 1800

 agtcctggag ctggtcacac aatatcagca gctcggcatc ttctggaagg 1850

 tcaattacaa ctttgaagat gagaccgtga ggaagtttct actgagccag 1900

 ttgcagaaaa ccaggcctgt gatcttggac ccaggcgaac ccacaggtga 1950

 cgtgggtgga ggggaccgtt ggtgttggca tcttctggac aaagaagcaa 2000

 aggttaggtt atcctctccc tgcttcaagg atgggactgg aaacccaata 2050

 ccaccttgga aagtgccgac aatgcagaca ccaggaagtt gtggagctag 2100

 gatccatcct attgtcaatg agatgttctc atccagaagc catagaatcc 2150

 tgaataataa ttctaaaaga aacttctgga gatcatctgg caatcgcttt 2200

 taaagactcg gctcaccgtg agaaagagtc actcacatcc attcttccct 2250

 tgatggtccc tattcctcct tcccttgcct tcttggactt cttgaaatca 2300

 atcaagactg caaacccttt cataaagctg ccttgctgaa ctcctctctg 2350

 caggagccct gcttaaaata gttgatgtca tcactttatg tgcatcttat 2400

 ttctgtcaac ttgtattttt ttttcttgta tttttccaat tagctcctcc 2450

 tttttccttc cagtctaaaa aaggaatcct ctgtgtcttc aaagcaaagc 2500

 tctttacttt ccccttggtt ctcataactc tgtgatcttg ctctcggtgc 2550

 ttccaactca tccacgtcct gtctgtttcc tctgtataca aaaccctttc 2600

 tgcccctgct gacacagaca tcctctatgc cagcagccag gccaaccctt 2650

 tcattagaac ttcaagctct ccaaaggctc agattataac tgttgtcata 2700

 tttatatgag gctgttgtct tttccttctg agcctgcctt tatcccccca 2750

 cccaggagta tcctcttgcc aaagcaaaag actttttcct tggctttagc 2800

 cttaaagata cttgaaggtc taggtgcttt aacctcacat accctcactt 2850

 aaacttttat cactgttgca tataccagtt gtgatacaat aaagaatgta 2900

 tctgg 2905

<210> 1258
<211> 727
<212> PRT
<213> Homo sapien

<400> 1258
 Met Gly Asn Gly Glu Ser Gln Leu Ser Ser Val Pro Ala Gln Lys
   1               5                  10                  15

 Leu Gly Trp Phe Ile Gln Glu Tyr Leu Lys Pro Tyr Glu Glu Cys
                  20                  25                  30

 Gln Thr Leu Ile Asp Glu Met Val Asn Thr Ile Cys Asp Val Cys
                  35                  40                  45

 Arg Asn Pro Glu Gln Phe Pro Leu Val Gln Gly Val Ala Ile Gly
                  50                  55                  60

 Gly Ser Tyr Gly Arg Lys Thr Val Leu Arg Gly Asn Ser Asp Gly
                  65                  70                  75

 Thr Leu Val Leu Phe Phe Ser Asp Leu Lys Gln Phe Gln Asp Gln
                  80                  85                  90

 Lys Arg Ser Gln Arg Asp Ile Leu Asp Lys Thr Gly Asp Lys Leu
                  95                 100                 105

 Lys Phe Cys Leu Phe Thr Lys Trp Leu Lys Asn Asn Phe Glu Ile
                 110                 115                 120

 Gln Lys Ser Leu Asp Gly Ser Thr Ile Gln Val Phe Thr Lys Asn
                 125                 130                 135

 Gln Arg Ile Ser Phe Glu Val Leu Ala Ala Phe Asn Ala Leu Ser
                 140                 145                 150

 Leu Asn Asp Asn Pro Ser Pro Trp Ile Tyr Arg Glu Leu Lys Arg
                 155                 160                 165

 Ser Leu Asp Lys Thr Asn Ala Ser Pro Gly Glu Phe Ala Val Cys
                 170                 175                 180

 Phe Thr Glu Leu Gln Gln Lys Phe Phe Asp Asn Arg Pro Gly Lys
                 185                 190                 195

 Leu Lys Asp Leu Ile Leu Leu Ile Lys His Trp His Gln Gln Cys
                 200                 205                 210

 Gln Lys Lys Ile Lys Asp Leu Pro Ser Leu Ser Pro Tyr Ala Leu
                 215                 220                 225

 Glu Leu Leu Thr Val Tyr Ala Trp Glu Gln Gly Cys Arg Lys Asp
                 230                 235                 240

 Asn Phe Asp Ile Ala Glu Gly Val Arg Thr Val Leu Glu Leu Ile
                 245                 250                 255

 Lys Cys Gln Glu Lys Leu Cys Ile Tyr Trp Met Val Asn Tyr Asn
                 260                 265                 270

 Phe Glu Asp Glu Thr Ile Arg Asn Ile Leu Leu His Gln Leu Gln
                 275                 280                 285

 Ser Ala Arg Pro Val Ile Leu Asp Pro Val Asp Pro Thr Asn Asn
                 290                 295                 300

 Val Ser Gly Asp Lys Ile Cys Trp Gln Trp Leu Lys Lys Glu Ala
                 305                 310                 315

 Gln Thr Trp Leu Thr Ser Pro Asn Leu Asp Asn Glu Leu Pro Ala
                 320                 325                 330

 Pro Ser Trp Asn Val Leu Pro Ala Pro Leu Phe Thr Thr Pro Gly
                 335                 340                 345

 His Leu Leu Asp Lys Phe Ile Lys Glu Phe Leu Gln Pro Asn Lys
                 350                 355                 360

 Cys Phe Leu Glu Gln Ile Asp Ser Ala Val Asn Ile Ile Arg Thr
                 365                 370                 375

 Phe Leu Lys Glu Asn Cys Phe Arg Gln Ser Thr Ala Lys Ile Gln
                 380                 385                 390

 Ile Val Arg Gly Gly Ser Thr Ala Lys Gly Thr Ala Leu Lys Thr
                 395                 400                 405

 Gly Ser Asp Ala Asp Leu Val Val Phe His Asn Ser Leu Lys Ser
                 410                 415                 420

 Tyr Thr Ser Gln Lys Asn Glu Arg His Lys Ile Val Lys Glu Ile
                 425                 430                 435

 His Glu Gln Leu Lys Ala Phe Trp Arg Glu Lys Glu Glu Glu Leu
                 440                 445                 450

 Glu Val Ser Phe Glu Pro Pro Lys Trp Lys Ala Pro Arg Val Leu
                 455                 460                 465

 Ser Phe Ser Leu Lys Ser Lys Val Leu Asn Glu Ser Val Ser Phe
                 470                 475                 480

 Asp Val Leu Pro Ala Phe Asn Ala Leu Gly Gln Leu Ser Ser Gly
                 485                 490                 495

 Ser Thr Pro Ser Pro Glu Val Tyr Ala Gly Leu Ile Asp Leu Tyr
                 500                 505                 510

 Lys Ser Ser Asp Leu Pro Gly Gly Glu Phe Ser Thr Cys Phe Thr
                 515                 520                 525

 Val Leu Gln Arg Asn Phe Ile Arg Ser Arg Pro Thr Lys Leu Lys
                 530                 535                 540

 Asp Leu Ile Arg Leu Val Lys His Trp Tyr Lys Glu Cys Glu Arg
                 545                 550                 555

 Lys Leu Lys Pro Lys Gly Ser Leu Pro Pro Lys Tyr Ala Leu Glu
                 560                 565                 570

 Leu Leu Thr Ile Tyr Ala Trp Glu Gln Gly Ser Gly Val Pro Asp
                 575                 580                 585

 Phe Asp Thr Ala Glu Gly Phe Arg Thr Val Leu Glu Leu Val Thr
                 590                 595                 600

 Gln Tyr Gln Gln Leu Gly Ile Phe Trp Lys Val Asn Tyr Asn Phe
                 605                 610                 615

 Glu Asp Glu Thr Val Arg Lys Phe Leu Leu Ser Gln Leu Gln Lys
                 620                 625                 630

 Thr Arg Pro Val Ile Leu Asp Pro Gly Glu Pro Thr Gly Asp Val
                 635                 640                 645

 Gly Gly Gly Asp Arg Trp Cys Trp His Leu Leu Asp Lys Glu Ala
                 650                 655                 660

 Lys Val Arg Leu Ser Ser Pro Cys Phe Lys Asp Gly Thr Gly Asn
                 665                 670                 675

 Pro Ile Pro Pro Trp Lys Val Pro Thr Met Gln Thr Pro Gly Ser
                 680                 685                 690

 Cys Gly Ala Arg Ile His Pro Ile Val Asn Glu Met Phe Ser Ser
                 695                 700                 705

 Arg Ser His Arg Ile Leu Asn Asn Asn Ser Lys Arg Asn Phe Trp
                 710                 715                 720

 Arg Ser Ser Gly Asn Arg Phe
                 725

<210> 1259
<211> 822
<212> DNA
<213> Homo sapien

<400> 1259
 ggagggggca tggcggatac tgtgttgttt gagtttcttc acacggagat 50

 ggtggctgag ctgtgggctc acgaccccga ccccggcccg ggggtgagcg 100

 ccgggctccg tggggaggaa gcgggggcca ccaagggaca gaagatgagc 150

 ctgtcggtcc tggagggtat ggggttccgt gtgggccagg ctctaggcga 200

 gaggctgccc cgggagacgc tggccttcag ggaggagctg gatgtcctca 250

 agttcttgtg caaagacctg tgggtggcgg tgttccagaa gcagatggac 300

 agcctgcgca ccaatcacca ggggacctac gtcctgcaag acaacagctt 350

 ccccctcctc ctcccgatgg cctctggcct gcagtatctg gaggaagcac 400

 ccaagttcct ggccttcacc tgcggcctcc tgcgcggcgc cctctatacc 450

 ctgggcattg agagcgtggt caccgcctcc gtggcagccc tgcccgtctg 500

 taagttccag gtggtgattc cgaaatccta agcctgcctc gcacctgctg 550

 agccgcactg ctgcccctgg cctcaccggc ctcaggagac ggtggggccg 600

 ctgcatttcg gggtggtctt gggaatccca ggccctaggg gtcacatttg 650

 ctcaggaagt gggtatcaaa ttgaggtggg ggtgtcagag gaggcaaagg 700

 ggtcccagct gcggtcagga ctgtggtggg attcccgcct cggcagcgtc 750

 actgcccagt agctgctcaa taaaggctgt gtgtgtggaa tctgaaaaaa 800

 aaaaaaaaaa aaaaaaaaaa aa 822

<210> 1260
<211> 173
<212> PRT
<213> Homo sapien

<400> 1260
 Met Ala Asp Thr Val Leu Phe Glu Phe Leu His Thr Glu Met Val
   1               5                  10                  15

 Ala Glu Leu Trp Ala His Asp Pro Asp Pro Gly Pro Gly Val Ser
                  20                  25                  30

 Ala Gly Leu Arg Gly Glu Glu Ala Gly Ala Thr Lys Gly Gln Lys
                  35                  40                  45

 Met Ser Leu Ser Val Leu Glu Gly Met Gly Phe Arg Val Gly Gln
                  50                  55                  60

 Ala Leu Gly Glu Arg Leu Pro Arg Glu Thr Leu Ala Phe Arg Glu
                  65                  70                  75

 Glu Leu Asp Val Leu Lys Phe Leu Cys Lys Asp Leu Trp Val Ala
                  80                  85                  90

 Val Phe Gln Lys Gln Met Asp Ser Leu Arg Thr Asn His Gln Gly
                  95                 100                 105

 Thr Tyr Val Leu Gln Asp Asn Ser Phe Pro Leu Leu Leu Pro Met
                 110                 115                 120

 Ala Ser Gly Leu Gln Tyr Leu Glu Glu Ala Pro Lys Phe Leu Ala
                 125                 130                 135

 Phe Thr Cys Gly Leu Leu Arg Gly Ala Leu Tyr Thr Leu Gly Ile
                 140                 145                 150

 Glu Ser Val Val Thr Ala Ser Val Ala Ala Leu Pro Val Cys Lys
                 155                 160                 165

 Phe Gln Val Val Ile Pro Lys Ser
                 170

<210> 1261
<211> 2838
<212> DNA
<213> Homo sapien

<400> 1261
 ctccggcccg gccccgagca ccgcctcccc agccagcgcc gccgcgatgg 50

 cggaggacag cgagtctgcg gccagccagc agagcctgga actggacgac 100

 caggacacgt gcgggataga cggggacaat gaggaggaga cggagcacgc 150

 caaaggaagt cctggagggt atttgggagc caaaaagaaa aagaagaaac 200

 agaagagaaa aaaggagaaa ccaaattccg gaggcaccaa gtcagactcg 250

 gcatctgatt cccaggagat taaaattcag cagccttcga aaaatcccag 300

 tgttccaatg cagaagttgc aggatatcca gagagcaatg gagctgctat 350

 ccgcatgcca gggcccagcc aggaacattg atgaggctgc aaagcacaga 400

 taccagtttt gggacacaca accggtacca aaactagatg aagtcataac 450

 atctcatggt gcaattgaac cagataaaga caacgtacgc caagaaccgt 500

 attctttgcc acagggtttt atgtgggaca ctttagactt gagtgatgcc 550

 gaagtgctca aggagttata cacgttgtta aatgagaatt acgtagaaga 600

 tgatgacaat atgttccgat ttgactattc acccgagttc ctgttgtggg 650

 ctctgcgtcc accaggctgg ctcctgcagt ggcactgtgg ggtcagagtg 700

 tcttcaaata aaaaactggt cgggttcata agtgccatcc cagcaaacat 750

 tcggatttat gacagtgtga agaagatggt agaaatcaac tttctttgtg 800

 ttcataagaa gttgagatcg aaacgggtag ccccagtgct aatccgagag 850

 atcactagaa gagtgaacct ggaagggatc ttccaggctg tgtacaccgc 900

 gggagtggtt cttcctaagc ccatagccac atgcagatac tggcatcgat 950

 cactaaaccc cagaaaattg gtagaagtga aattttctca cttgagtaga 1000

 aatatgactt tacagagaac aatgaagcta tacagacttc cagatgttac 1050

 aaagacttca ggtttgagac caatggaacc aaaagatatc aaatcagttc 1100

 gagaattaat caacacttac ctgaagcagt ttcatctggc tccagtgatg 1150

 gatgaagagg aagtagccca ctggttcctc ccccgggagc acattattga 1200

 cacgtttgta gtggagagcc ccaacggtaa actgactgat ttcctgagct 1250

 tctatacgct cccctccacg gtgatgcacc accctgctca caagagcctc 1300

 aaagccgcct actcattcta caacatccac acagagacgc ccctgctgga 1350

 cctcatgagc gacgcgctca tcctggctaa atcgaaagga tttgatgtat 1400

 tcaatgcact ggatttgatg gaaaataaga cattcttgga aaaactcaag 1450

 tttggtatag gagatggcaa tttgcagtat tacctgtaca attggaggtg 1500

 tccaggtaca gattctgaaa aggttggact agtactacaa tagatggata 1550

 tttttatttc tagaactctg acatcatcat ttgttaatat ttaatgattt 1600

 ctggaactgc cattccaaag aagaataaaa gcacaactca agtgaaattg 1650

 aagtagtcga taatcagaaa agatgacaaa agtccacatg tgacatttgt 1700

 acgtttctag ctagaatgtt aaacttcatc ctttttttac tgttgaccta 1750

 tttgtgggag ggatgaaagg ctacaaagag cacattcttg taattttcaa 1800

 atttttgcct gtctcttgaa gaggtatttt ttcaccctta gaaaagggac 1850

 tgtttttcta tggactaagt agaagttaca gagtcatgta agaaaatctt 1900

 tgctattgtg tggagagaaa ttgctgcatt tctgtttctt aagtgatggt 1950

 acatttgtcc atgtaacaga acaaaagatc catttggaaa ttttttttac 2000

 tggtatcacc ttacatggta tcactgggaa catttatgga atcaacactt 2050

 ctgtagctca gtgacaggtg gtggttgttt aagtgcagag caatattaaa 2100

 tgtactggtg actagtacat gtatttctcc ataagcagag ttgccgaatc 2150

 aataaacatg caagtttgta ctttgatctt taccaggtca gtggattgct 2200

 tcaaaagcag agttttgtgc aagcactcac tgtgctctct gaaagagcct 2250

 gaggccgggc gtggtggctc acgcctgtaa tcccagcact ttgggaggcc 2300

 aaggtgggca gatcatgagg tcaggagatc gagaccattc tggccaacat 2350

 agtgaaaccc catctctact aaaaatacaa aaattagccg ggcgtggtgg 2400

 cgtgtgcctg tagtcccagc tgcttgggag gctgaggcag gagaatcgct 2450

 tgaacctgag aggtgaggtt gcagtgagcc gagatcgagc cactgcactc 2500

 cagcctgggt gacagagcgt gagactccgt ctcaaaaaaa aaaaaaaaag 2550

 aaagagcctg tacccgcgac taactagact tttcttgctg ttgtgcaaag 2600

 ttcagtttct tctcagcaac atcaaggata tatgaagaaa aggaaataaa 2650

 aaactgtaaa gtcaaaagag atgcctggtg gaacttattc gtgctatcag 2700

 ggcattgata gtttgaatgt ttttattact tatgcaaaat tgcacatact 2750

 cctctatgct gattttatca tgaaaactgt catgtgtcat gctaatggaa 2800

 aatgtcttat ttgtaaataa gtattcataa ttttgccg 2838

<210> 1262
<211> 498
<212> PRT
<213> Homo sapien

<400> 1262
 Met Ala Glu Asp Ser Glu Ser Ala Ala Ser Gln Gln Ser Leu Glu
   1               5                  10                  15

 Leu Asp Asp Gln Asp Thr Cys Gly Ile Asp Gly Asp Asn Glu Glu
                  20                  25                  30

 Glu Thr Glu His Ala Lys Gly Ser Pro Gly Gly Tyr Leu Gly Ala
                  35                  40                  45

 Lys Lys Lys Lys Lys Lys Gln Lys Arg Lys Lys Glu Lys Pro Asn
                  50                  55                  60

 Ser Gly Gly Thr Lys Ser Asp Ser Ala Ser Asp Ser Gln Glu Ile
                  65                  70                  75

 Lys Ile Gln Gln Pro Ser Lys Asn Pro Ser Val Pro Met Gln Lys
                  80                  85                  90

 Leu Gln Asp Ile Gln Arg Ala Met Glu Leu Leu Ser Ala Cys Gln
                  95                 100                 105

 Gly Pro Ala Arg Asn Ile Asp Glu Ala Ala Lys His Arg Tyr Gln
                 110                 115                 120

 Phe Trp Asp Thr Gln Pro Val Pro Lys Leu Asp Glu Val Ile Thr
                 125                 130                 135

 Ser His Gly Ala Ile Glu Pro Asp Lys Asp Asn Val Arg Gln Glu
                 140                 145                 150

 Pro Tyr Ser Leu Pro Gln Gly Phe Met Trp Asp Thr Leu Asp Leu
                 155                 160                 165

 Ser Asp Ala Glu Val Leu Lys Glu Leu Tyr Thr Leu Leu Asn Glu
                 170                 175                 180

 Asn Tyr Val Glu Asp Asp Asp Asn Met Phe Arg Phe Asp Tyr Ser
                 185                 190                 195

 Pro Glu Phe Leu Leu Trp Ala Leu Arg Pro Pro Gly Trp Leu Leu
                 200                 205                 210

 Gln Trp His Cys Gly Val Arg Val Ser Ser Asn Lys Lys Leu Val
                 215                 220                 225

 Gly Phe Ile Ser Ala Ile Pro Ala Asn Ile Arg Ile Tyr Asp Ser
                 230                 235                 240

 Val Lys Lys Met Val Glu Ile Asn Phe Leu Cys Val His Lys Lys
                 245                 250                 255

 Leu Arg Ser Lys Arg Val Ala Pro Val Leu Ile Arg Glu Ile Thr
                 260                 265                 270

 Arg Arg Val Asn Leu Glu Gly Ile Phe Gln Ala Val Tyr Thr Ala
                 275                 280                 285

 Gly Val Val Leu Pro Lys Pro Ile Ala Thr Cys Arg Tyr Trp His
                 290                 295                 300

 Arg Ser Leu Asn Pro Arg Lys Leu Val Glu Val Lys Phe Ser His
                 305                 310                 315

 Leu Ser Arg Asn Met Thr Leu Gln Arg Thr Met Lys Leu Tyr Arg
                 320                 325                 330

 Leu Pro Asp Val Thr Lys Thr Ser Gly Leu Arg Pro Met Glu Pro
                 335                 340                 345

 Lys Asp Ile Lys Ser Val Arg Glu Leu Ile Asn Thr Tyr Leu Lys
                 350                 355                 360

 Gln Phe His Leu Ala Pro Val Met Asp Glu Glu Glu Val Ala His
                 365                 370                 375

 Trp Phe Leu Pro Arg Glu His Ile Ile Asp Thr Phe Val Val Glu
                 380                 385                 390

 Ser Pro Asn Gly Lys Leu Thr Asp Phe Leu Ser Phe Tyr Thr Leu
                 395                 400                 405

 Pro Ser Thr Val Met His His Pro Ala His Lys Ser Leu Lys Ala
                 410                 415                 420

 Ala Tyr Ser Phe Tyr Asn Ile His Thr Glu Thr Pro Leu Leu Asp
                 425                 430                 435

 Leu Met Ser Asp Ala Leu Ile Leu Ala Lys Ser Lys Gly Phe Asp
                 440                 445                 450

 Val Phe Asn Ala Leu Asp Leu Met Glu Asn Lys Thr Phe Leu Glu
                 455                 460                 465

 Lys Leu Lys Phe Gly Ile Gly Asp Gly Asn Leu Gln Tyr Tyr Leu
                 470                 475                 480

 Tyr Asn Trp Arg Cys Pro Gly Thr Asp Ser Glu Lys Val Gly Leu
                 485                 490                 495

 Val Leu Gln


<210> 1263
<211> 2838
<212> DNA
<213> Homo sapien

<400> 1263
 ctccggcccg gccccgagca ccgcctcccc agccagcgcc gccgcgatgg 50

 cggaggacag cgagtctgcg gccagccagc agagcctgga actggacgac 100

 caggacacgt gcgggataga cggggacaat gaggaggaga cggagcacgc 150

 caaaggaagt cctggagggt atttgggagc caaaaagaaa aagaagaaac 200

 agaagagaaa aaaggagaaa ccaaattccg gaggcaccaa gtcagactcg 250

 gcatctgatt cccaggagat taaaattcag cagccttcga aaaatcccag 300

 tgttccaatg cagaagttgc aggatatcca gagagcaatg gagctgctat 350

 ccgcatgcca gggcccagcc aggaacattg atgaggctgc aaagcacaga 400

 taccagtttt gggacacaca accggtacca aaactagatg aagtcataac 450

 atctcatggt gcaattgaac cagataaaga caacgtacgc caagaaccgt 500

 attctttgcc acagggtttt atgtgggaca ctttagactt gagtgatgcc 550

 gaagtgctca aggagttata cacgttgtta aatgagaatt acgtagaaga 600

 tgatgacaat atgttccgat ttgactattc acccgagttc ctgttgtggg 650

 ctctgcgtcc accaggctgg ctcctgcagt ggcactgtgg ggtcagagtg 700

 tcttcaaata aaaaactggt cgggttcata agtgccatcc cagcaaacat 750

 tcggatttat gacagtgtga agaagatggt agaaatcaac tttctttgtg 800

 ttcataagaa gttgagatcg aaacgggtag ccccagtgct aatccgagag 850

 atcactagaa gagtgaacct ggaagggatc ttccaggctg tgtacaccgc 900

 gggagtggtt cttcctaagc ccatagccac atgcagatac tggcatcgat 950

 cactaaaccc cagaaaattg gtagaagtga aattttctca cttgagtaga 1000

 aatatgactt tacagagaac aatgaagcta tacagacttc cagatgttac 1050

 aaagacttca ggtttgagac caatggaacc aaaagatatc aaatcagttc 1100

 gagaattaat caacacttac ctgaagcagt ttcatctggc tccagtgatg 1150

 gatgaagagg aagtagccca ctggttcctc ccccgggagc acattattga 1200

 cacgtttgta gtggagagcc ccaacggtaa actgactgat ttcctgagct 1250

 tctatacgct cccctccacg gtgatgcacc accctgctca caagagcctc 1300

 aaagccgcct actcattcta caacatccac acagagacgc ccctgctgga 1350

 cctcatgagc gacgcgctca tcctggctaa atcgaaagga tttgatgtat 1400

 tcaatgcact ggatttgatg gaaaataaga cattcttgga aaaactcaag 1450

 tttggtatag gagatggcaa tttgcagtat tacctgtaca attggaggtg 1500

 tccaggtaca gattctgaaa aggttggact agtactacaa tagatggata 1550

 tttttatttc tagaactctg acatcatcat ttgttaatat ttaatgattt 1600

 ctggaactgc cattccaaag aagaataaaa gcacaactca agtgaaattg 1650

 aagtagtcga taatcagaaa agatgacaaa agtccacatg tgacatttgt 1700

 acgtttctag ctagaatgtt aaacttcatc ctttttttac tgttgaccta 1750

 tttgtgggag ggatgaaagg ctacaaagag cacattcttg taattttcaa 1800

 atttttgcct gtctcttgaa gaggtatttt ttcaccctta gaaaagggac 1850

 tgtttttcta tggactaagt agaagttaca gagtcatgta agaaaatctt 1900

 tgctattgtg tggagagaaa ttgctgcatt tctgtttctt aagtgatggt 1950

 acatttgtcc atgtaacaga acaaaagatc catttggaaa ttttttttac 2000

 tggtatcacc ttacatggta tcactgggaa catttatgga atcaacactt 2050

 ctgtagctca gtgacaggtg gtggttgttt aagtgcagag caatattaaa 2100

 tgtactggtg actagtacat gtatttctcc ataagcagag ttgccgaatc 2150

 aataaacatg caagtttgta ctttgatctt taccaggtca gtggattgct 2200

 tcaaaagcag agttttgtgc aagcactcac tgtgctctct gaaagagcct 2250

 gaggccgggc gtggtggctc acgcctgtaa tcccagcact ttgggaggcc 2300

 aaggtgggca gatcatgagg tcaggagatc gagaccattc tggccaacat 2350

 agtgaaaccc catctctact aaaaatacaa aaattagccg ggcgtggtgg 2400

 cgtgtgcctg tagtcccagc tgcttgggag gctgaggcag gagaatcgct 2450

 tgaacctgag aggtgaggtt gcagtgagcc gagatcgagc cactgcactc 2500

 cagcctgggt gacagagcgt gagactccgt ctcaaaaaaa aaaaaaaaag 2550

 aaagagcctg tacccgcgac taactagact tttcttgctg ttgtgcaaag 2600

 ttcagtttct tctcagcaac atcaaggata tatgaagaaa aggaaataaa 2650

 aaactgtaaa gtcaaaagag atgcctggtg gaacttattc gtgctatcag 2700

 ggcattgata gtttgaatgt ttttattact tatgcaaaat tgcacatact 2750

 cctctatgct gattttatca tgaaaactgt catgtgtcat gctaatggaa 2800

 aatgtcttat ttgtaaataa gtattcataa ttttgccg 2838

<210> 1264
<211> 498
<212> PRT
<213> Homo sapien

<400> 1264
 Met Ala Glu Asp Ser Glu Ser Ala Ala Ser Gln Gln Ser Leu Glu
   1               5                  10                  15

 Leu Asp Asp Gln Asp Thr Cys Gly Ile Asp Gly Asp Asn Glu Glu
                  20                  25                  30

 Glu Thr Glu His Ala Lys Gly Ser Pro Gly Gly Tyr Leu Gly Ala
                  35                  40                  45

 Lys Lys Lys Lys Lys Lys Gln Lys Arg Lys Lys Glu Lys Pro Asn
                  50                  55                  60

 Ser Gly Gly Thr Lys Ser Asp Ser Ala Ser Asp Ser Gln Glu Ile
                  65                  70                  75

 Lys Ile Gln Gln Pro Ser Lys Asn Pro Ser Val Pro Met Gln Lys
                  80                  85                  90

 Leu Gln Asp Ile Gln Arg Ala Met Glu Leu Leu Ser Ala Cys Gln
                  95                 100                 105

 Gly Pro Ala Arg Asn Ile Asp Glu Ala Ala Lys His Arg Tyr Gln
                 110                 115                 120

 Phe Trp Asp Thr Gln Pro Val Pro Lys Leu Asp Glu Val Ile Thr
                 125                 130                 135

 Ser His Gly Ala Ile Glu Pro Asp Lys Asp Asn Val Arg Gln Glu
                 140                 145                 150

 Pro Tyr Ser Leu Pro Gln Gly Phe Met Trp Asp Thr Leu Asp Leu
                 155                 160                 165

 Ser Asp Ala Glu Val Leu Lys Glu Leu Tyr Thr Leu Leu Asn Glu
                 170                 175                 180

 Asn Tyr Val Glu Asp Asp Asp Asn Met Phe Arg Phe Asp Tyr Ser
                 185                 190                 195

 Pro Glu Phe Leu Leu Trp Ala Leu Arg Pro Pro Gly Trp Leu Leu
                 200                 205                 210

 Gln Trp His Cys Gly Val Arg Val Ser Ser Asn Lys Lys Leu Val
                 215                 220                 225

 Gly Phe Ile Ser Ala Ile Pro Ala Asn Ile Arg Ile Tyr Asp Ser
                 230                 235                 240

 Val Lys Lys Met Val Glu Ile Asn Phe Leu Cys Val His Lys Lys
                 245                 250                 255

 Leu Arg Ser Lys Arg Val Ala Pro Val Leu Ile Arg Glu Ile Thr
                 260                 265                 270

 Arg Arg Val Asn Leu Glu Gly Ile Phe Gln Ala Val Tyr Thr Ala
                 275                 280                 285

 Gly Val Val Leu Pro Lys Pro Ile Ala Thr Cys Arg Tyr Trp His
                 290                 295                 300

 Arg Ser Leu Asn Pro Arg Lys Leu Val Glu Val Lys Phe Ser His
                 305                 310                 315

 Leu Ser Arg Asn Met Thr Leu Gln Arg Thr Met Lys Leu Tyr Arg
                 320                 325                 330

 Leu Pro Asp Val Thr Lys Thr Ser Gly Leu Arg Pro Met Glu Pro
                 335                 340                 345

 Lys Asp Ile Lys Ser Val Arg Glu Leu Ile Asn Thr Tyr Leu Lys
                 350                 355                 360

 Gln Phe His Leu Ala Pro Val Met Asp Glu Glu Glu Val Ala His
                 365                 370                 375

 Trp Phe Leu Pro Arg Glu His Ile Ile Asp Thr Phe Val Val Glu
                 380                 385                 390

 Ser Pro Asn Gly Lys Leu Thr Asp Phe Leu Ser Phe Tyr Thr Leu
                 395                 400                 405

 Pro Ser Thr Val Met His His Pro Ala His Lys Ser Leu Lys Ala
                 410                 415                 420

 Ala Tyr Ser Phe Tyr Asn Ile His Thr Glu Thr Pro Leu Leu Asp
                 425                 430                 435

 Leu Met Ser Asp Ala Leu Ile Leu Ala Lys Ser Lys Gly Phe Asp
                 440                 445                 450

 Val Phe Asn Ala Leu Asp Leu Met Glu Asn Lys Thr Phe Leu Glu
                 455                 460                 465

 Lys Leu Lys Phe Gly Ile Gly Asp Gly Asn Leu Gln Tyr Tyr Leu
                 470                 475                 480

 Tyr Asn Trp Arg Cys Pro Gly Thr Asp Ser Glu Lys Val Gly Leu
                 485                 490                 495

 Val Leu Gln


<210> 1265
<211> 2403
<212> DNA
<213> Homo sapien

<400> 1265
 tttgcaggtg cctcaggaac cctgaagctg ggctgagcca tgatgctgct 50

 gccagaaccc ctgcagaggg cctggtttca ggagactcag agtcctctgt 100

 gaaaaagccc ttggagagcg ccccagcagg gctgcacttg gctcctgtga 150

 ggaaggggct caggggtctg ggcccctccg cctgggccgg gctgggagcc 200

 aggcgggcgg ctgggctgca gcaatggacc gtgagctggc ccagcccgcg 250

 tccgtgctga gcctgcctgt cgtctgtggc catgcccatc atgggctcct 300

 cggtgtacat cacggtggag ctggccattg ctgtgctggc catcctgggc 350

 aatgtgctgg tgtgctgggc cgtgtggctc aacagcaacc tgcagaacgt 400

 caccaactac tttgtggtgt cactggcggc ggccgacatc gcagtgggtg 450

 tgctcgccat cccctttgcc atcaccatca gcaccgggtt ctgcgctgcc 500

 tgccacggct gcctcttcat tgcctgcttc gtcctggtcc tcacgcagag 550

 ctccatcttc agtctcctgg ccatcgccat tgaccgctac attgccatcc 600

 gcatcccgct ccggtacaat ggcttggtga ccggcacgag ggctaagggc 650

 atcattgcca tctgctgggt gctgtcgttt gccatcggcc tgactcccat 700

 gctaggttgg aacaactgcg gtcagccaaa ggagggcaag aaccactccc 750

 agggctgcgg ggagggccaa gtggcctgtc tctttgagga tgtggtcccc 800

 atgaactaca tggtgtactt caacttcttt gcctgtgtgc tggtgcccct 850

 gctgctcatg ctgggtgtct atttgcggat cttcctggcg gcgcgacgac 900

 agctgaagca gatggagagc cagcctctgc cgggggagcg ggcacggtcc 950

 acactgcaga aggaggtcca tgctgccaag tcactggcca tcattgtggg 1000

 gctctttgcc ctctgctggc tgcccctaca catcatcaac tgcttcactt 1050

 tcttctgccc cgactgcagc cacgcccctc tctggctcat gtacctggcc 1100

 atcgtcctct cccacaccaa ttcggttgtg aatcccttca tctacgccta 1150

 ccgtatccgc gagttccgcc agaccttccg caagatcatt cgcagccacg 1200

 tcctgaggca gcaagaacct ttcaaggcag ctggcaccag tgcccgggtc 1250

 ttggcagctc atggcagtga cggagagcag gtcagcctcc gtctcaacgg 1300

 ccacccgcca ggagtgtggg ccaacggcag tgctccccac cctgagcgga 1350

 ggcccaatgg ctatgccctg gggctggtga gtggagggag tgcccaagag 1400

 tcccagggga acacgggcct cccagacgtg gagctcctta gccatgagct 1450

 caagggagtg tgcccagagc cccctggcct agatgacccc ctggcccagg 1500

 atggagcagg agtgtcctga tgattcatgg agtttgcccc ttcctaaggg 1550

 aaggagatct ttatctttct ggttggcttg accagtcacg ttgggagaag 1600

 agagagagtg ccaggagacc ctgagggcag ccggttccta ctttggactg 1650

 agagaaggga gccccaggct ggagcagcat gaggcccagc aagaagggct 1700

 tgggttctga ggaagcagat gtttcatgct gtgaggcctt gcaccaggtg 1750

 ggggccacag caccagcagc atctttgctg ggcaggccca gccctccact 1800

 gcagaagcat ctggaagcac caccttgtct ccacagagca gcttgggcac 1850

 agcagactgg cctggccctg agactgggga gtggctccaa tagcctcctg 1900

 ccacccacac accactctcc ctagactctc ctagggttca ggagctgctg 1950

 ggcccagagg tgacatttga cttttttcca ggaaaaatgt aagtgtgagg 2000

 aaaccctttt tattttatta cctttcactc tctggctgct gggtctgccg 2050

 tcggtcctgc tgctaacctg gcaccagagc ctctgcccgg ggagcctcag 2100

 gcagtcctct cctgctgtca cagctgccat ccacttctca gtcccagggc 2150

 catctcttgg agtgacaaag ctgggatcaa ggatagggag ttgtaacaga 2200

 gcagtgccag agcatgggcc caggtcccag gggagaggtt ggggctggca 2250

 ggccactggc atgtgctgag tagcgcagag ctacccagtg agaggccttg 2300

 tctaactgcc tttccttcta aagggaatgt ttttttctga gataaaataa 2350

 aaacgagcca catcgtgttt taagcttgtc caaatgaaaa aaaaaaaaaa 2400

 aaa 2403

<210> 1266
<211> 412
<212> PRT
<213> Homo sapien

<400> 1266
 Met Pro Ile Met Gly Ser Ser Val Tyr Ile Thr Val Glu Leu Ala
   1               5                  10                  15

 Ile Ala Val Leu Ala Ile Leu Gly Asn Val Leu Val Cys Trp Ala
                  20                  25                  30

 Val Trp Leu Asn Ser Asn Leu Gln Asn Val Thr Asn Tyr Phe Val
                  35                  40                  45

 Val Ser Leu Ala Ala Ala Asp Ile Ala Val Gly Val Leu Ala Ile
                  50                  55                  60

 Pro Phe Ala Ile Thr Ile Ser Thr Gly Phe Cys Ala Ala Cys His
                  65                  70                  75

 Gly Cys Leu Phe Ile Ala Cys Phe Val Leu Val Leu Thr Gln Ser
                  80                  85                  90

 Ser Ile Phe Ser Leu Leu Ala Ile Ala Ile Asp Arg Tyr Ile Ala
                  95                 100                 105

 Ile Arg Ile Pro Leu Arg Tyr Asn Gly Leu Val Thr Gly Thr Arg
                 110                 115                 120

 Ala Lys Gly Ile Ile Ala Ile Cys Trp Val Leu Ser Phe Ala Ile
                 125                 130                 135

 Gly Leu Thr Pro Met Leu Gly Trp Asn Asn Cys Gly Gln Pro Lys
                 140                 145                 150

 Glu Gly Lys Asn His Ser Gln Gly Cys Gly Glu Gly Gln Val Ala
                 155                 160                 165

 Cys Leu Phe Glu Asp Val Val Pro Met Asn Tyr Met Val Tyr Phe
                 170                 175                 180

 Asn Phe Phe Ala Cys Val Leu Val Pro Leu Leu Leu Met Leu Gly
                 185                 190                 195

 Val Tyr Leu Arg Ile Phe Leu Ala Ala Arg Arg Gln Leu Lys Gln
                 200                 205                 210

 Met Glu Ser Gln Pro Leu Pro Gly Glu Arg Ala Arg Ser Thr Leu
                 215                 220                 225

 Gln Lys Glu Val His Ala Ala Lys Ser Leu Ala Ile Ile Val Gly
                 230                 235                 240

 Leu Phe Ala Leu Cys Trp Leu Pro Leu His Ile Ile Asn Cys Phe
                 245                 250                 255

 Thr Phe Phe Cys Pro Asp Cys Ser His Ala Pro Leu Trp Leu Met
                 260                 265                 270

 Tyr Leu Ala Ile Val Leu Ser His Thr Asn Ser Val Val Asn Pro
                 275                 280                 285

 Phe Ile Tyr Ala Tyr Arg Ile Arg Glu Phe Arg Gln Thr Phe Arg
                 290                 295                 300

 Lys Ile Ile Arg Ser His Val Leu Arg Gln Gln Glu Pro Phe Lys
                 305                 310                 315

 Ala Ala Gly Thr Ser Ala Arg Val Leu Ala Ala His Gly Ser Asp
                 320                 325                 330

 Gly Glu Gln Val Ser Leu Arg Leu Asn Gly His Pro Pro Gly Val
                 335                 340                 345

 Trp Ala Asn Gly Ser Ala Pro His Pro Glu Arg Arg Pro Asn Gly
                 350                 355                 360

 Tyr Ala Leu Gly Leu Val Ser Gly Gly Ser Ala Gln Glu Ser Gln
                 365                 370                 375

 Gly Asn Thr Gly Leu Pro Asp Val Glu Leu Leu Ser His Glu Leu
                 380                 385                 390

 Lys Gly Val Cys Pro Glu Pro Pro Gly Leu Asp Asp Pro Leu Ala
                 395                 400                 405

 Gln Asp Gly Ala Gly Val Ser
                 410

<210> 1267
<211> 2771
<212> DNA
<213> Homo sapien

<400> 1267
 ggccacaggc cagcgccact ctgccaggct cccggccatc gcccgcctgg 50

 tgcgccgccc gccagctctt tgcccgcgcg gggccgcccg ccgcgggctc 100

 agggcagacc atgcgcccgc caagtccgct gcccgcccgc tggctatgcg 150

 tgctggcagg cgccctcgcc tgggcccttg ggccggcggg cggccaggcg 200

 gccaggctgc aggaggagtg tgactatgtg cagatgatcg aggtgcagca 250

 caagcagtgc ctggaggagg cccagctgga gaatgagaca ataggctgca 300

 gcaagatgtg ggacaacctc acctgctggc cagccacccc tcggggccag 350

 gtagttgtct tggcctgtcc cctcatcttc aagctcttct cctccattca 400

 aggccgcaat gtaagccgca gctgcaccga cgaaggctgg acgcacctgg 450

 agcctggccc gtaccccatt gcctgtggtt tggatgacaa ggcagcgagt 500

 ttggatgagc agcagaccat gttctacggt tctgtgaaga ccggctacac 550

 cattggctac ggcctgtccc tcgccaccct tctggtcgcc acagctatcc 600

 tgagcctgtt caggaagctc cactgcacgc ggaactacat ccacatgcac 650

 ctcttcatat ccttcatcct gagggctgcc gctgtcttca tcaaagactt 700

 ggccctcttc gacagcgggg agtcggacca gtgctccgag ggctcggtgg 750

 gctgtaaggc agccatggtc tttttccaat attgtgtcat ggctaacttc 800

 ttctggctgc tggtggaggg cctctacctg tacaccctgc ttgccgtctc 850

 cttcttctct gagcggaagt acttctgggg gtacatactc atcggctggg 900

 gggtacccag cacattcacc atggtgtgga ccatcgccag gatccatttt 950

 gaggattatg ggtgctggga caccatcaac tcctcactgt ggtggatcat 1000

 aaagggcccc atcctcacct ccatcttggt aaacttcatc ctgtttattt 1050

 gcatcatccg aatcctgctt cagaaactgc ggcccccaga tatcaggaag 1100

 agtgacagca gtccatactc aaggctagcc aggtccacac tcctgctgat 1150

 ccccctgttt ggagtacact acatcatgtt cgccttcttt ccggacaatt 1200

 ttaagcctga agtgaagatg gtctttgagc tcgtcgtggg gtctttccag 1250

 ggttttgtgg tggctatcct ctactgcttc ctcaatggtg aggtgcaggc 1300

 ggagctgagg cggaagtggc ggcgctggca cctgcagggc gtcctgggct 1350

 ggaaccccaa ataccggcac ccgtcgggag gcagcaacgg cgccacgtgc 1400

 agcacgcagg tttccatgct gacccgcgtc agcccaggtg cccgccgctc 1450

 ctccagcttc caagccgaag tctccctggt ctgaccacca ggatcccagg 1500

 ggcccaaggc ggcccctccc gccccttccc actcaccccg gcagacgccg 1550

 gggacagagg cctgcccggg cgcggccagc cccggccctg ggctcggagg 1600

 ctgcccccgg ccccctggtc tctggtccgg acactcctag agaacgcagc 1650

 cctagagcct gcctggagcg tttctagcaa gtgagagaga tgggagctcc 1700

 tctcctggag gattgcaggt ggaactcagt cattagactc ctcctccaaa 1750

 ggccccctac gccaatcaag ggcaaaaagt ctacatactt tcatcctgac 1800

 tctgccccct gctggctctt ctgcccaatt ggaggaaagc aaccggtgga 1850

 tcctcaaaca acactggtgt gacctgaggg cagaaaggtt ctgcccgggg 1900

 aaggtcacca gcaccaacac cacggtagtg cctgaaattt caccattgct 1950

 gtcaagttcc tttgggttaa gcattaccac tcaggcattt gactgaagat 2000

 gcagctcact accctattct ctctttacgc ttagttatca gctttttaaa 2050

 gtgggttatt ctggagtttt tgtttggaga gcacacctat cttagtggtt 2100

 ccccaccgaa gtggactggc ccctgggtca gtctggtggg aggacggtgc 2150

 aacccaagga ctgagggact ctgaagcctc tgggaaatga gaaggcagcc 2200

 accagcgaat gctaggtctc ggactaagcc tacctgctct ccaagtctca 2250

 gtggcttcat ctgtcaagtg ggatctgtca caccagccat acttatctct 2300

 ctgtgctgtg gaagcaacag gaatcaagag ctgccctcct tgtccaccca 2350

 cctatgtgcc aactgttgta actaggctca gagatgtgca cccatgggct 2400

 ctgacagaaa gcagatacct caccctgcta cacatacagg atttgaactc 2450

 agatctgtct gataggaatg tgaaagcacg gactcttact gctaactttt 2500

 gtgtatcgta accagccaga tcctcttggt tatttgttta ccacttgtat 2550

 tattaatgcc attatcctga attccccttg ccaccccacc ctccctggcg 2600

 tgtggctgag gaggcctcca tctcatgtat catctggata ggagcctgct 2650

 ggtcacagcc tcctctgtct gcccttcacc ccagtggcca ctcagcttcc 2700

 tacccacacc tctgccagaa gatcccctca ggactgcaac aggcttgtgc 2750

 aacaataaat gttggcttgg a 2771

<210> 1268
<211> 457
<212> PRT
<213> Homo sapien

<400> 1268
 Met Arg Pro Pro Ser Pro Leu Pro Ala Arg Trp Leu Cys Val Leu
   1               5                  10                  15

 Ala Gly Ala Leu Ala Trp Ala Leu Gly Pro Ala Gly Gly Gln Ala
                  20                  25                  30

 Ala Arg Leu Gln Glu Glu Cys Asp Tyr Val Gln Met Ile Glu Val
                  35                  40                  45

 Gln His Lys Gln Cys Leu Glu Glu Ala Gln Leu Glu Asn Glu Thr
                  50                  55                  60

 Ile Gly Cys Ser Lys Met Trp Asp Asn Leu Thr Cys Trp Pro Ala
                  65                  70                  75

 Thr Pro Arg Gly Gln Val Val Val Leu Ala Cys Pro Leu Ile Phe
                  80                  85                  90

 Lys Leu Phe Ser Ser Ile Gln Gly Arg Asn Val Ser Arg Ser Cys
                  95                 100                 105

 Thr Asp Glu Gly Trp Thr His Leu Glu Pro Gly Pro Tyr Pro Ile
                 110                 115                 120

 Ala Cys Gly Leu Asp Asp Lys Ala Ala Ser Leu Asp Glu Gln Gln
                 125                 130                 135

 Thr Met Phe Tyr Gly Ser Val Lys Thr Gly Tyr Thr Ile Gly Tyr
                 140                 145                 150

 Gly Leu Ser Leu Ala Thr Leu Leu Val Ala Thr Ala Ile Leu Ser
                 155                 160                 165

 Leu Phe Arg Lys Leu His Cys Thr Arg Asn Tyr Ile His Met His
                 170                 175                 180

 Leu Phe Ile Ser Phe Ile Leu Arg Ala Ala Ala Val Phe Ile Lys
                 185                 190                 195

 Asp Leu Ala Leu Phe Asp Ser Gly Glu Ser Asp Gln Cys Ser Glu
                 200                 205                 210

 Gly Ser Val Gly Cys Lys Ala Ala Met Val Phe Phe Gln Tyr Cys
                 215                 220                 225

 Val Met Ala Asn Phe Phe Trp Leu Leu Val Glu Gly Leu Tyr Leu
                 230                 235                 240

 Tyr Thr Leu Leu Ala Val Ser Phe Phe Ser Glu Arg Lys Tyr Phe
                 245                 250                 255

 Trp Gly Tyr Ile Leu Ile Gly Trp Gly Val Pro Ser Thr Phe Thr
                 260                 265                 270

 Met Val Trp Thr Ile Ala Arg Ile His Phe Glu Asp Tyr Gly Cys
                 275                 280                 285

 Trp Asp Thr Ile Asn Ser Ser Leu Trp Trp Ile Ile Lys Gly Pro
                 290                 295                 300

 Ile Leu Thr Ser Ile Leu Val Asn Phe Ile Leu Phe Ile Cys Ile
                 305                 310                 315

 Ile Arg Ile Leu Leu Gln Lys Leu Arg Pro Pro Asp Ile Arg Lys
                 320                 325                 330

 Ser Asp Ser Ser Pro Tyr Ser Arg Leu Ala Arg Ser Thr Leu Leu
                 335                 340                 345

 Leu Ile Pro Leu Phe Gly Val His Tyr Ile Met Phe Ala Phe Phe
                 350                 355                 360

 Pro Asp Asn Phe Lys Pro Glu Val Lys Met Val Phe Glu Leu Val
                 365                 370                 375

 Val Gly Ser Phe Gln Gly Phe Val Val Ala Ile Leu Tyr Cys Phe
                 380                 385                 390

 Leu Asn Gly Glu Val Gln Ala Glu Leu Arg Arg Lys Trp Arg Arg
                 395                 400                 405

 Trp His Leu Gln Gly Val Leu Gly Trp Asn Pro Lys Tyr Arg His
                 410                 415                 420

 Pro Ser Gly Gly Ser Asn Gly Ala Thr Cys Ser Thr Gln Val Ser
                 425                 430                 435

 Met Leu Thr Arg Val Ser Pro Gly Ala Arg Arg Ser Ser Ser Phe
                 440                 445                 450

 Gln Ala Glu Val Ser Leu Val
                 455

<210> 1269
<211> 2667
<212> DNA
<213> Homo sapien

<400> 1269
 gagggtgggt cgaccccggg aattcggcac gagcggcggc ggggccaccc 50

 gcgagtccag cgtcgccgca gccccccaat gcggccgcga gaagcagcgg 100

 gggggcaggc gatcgaagga gccttcacgt aaatgggtcc agtcatgcct 150

 cccagtaaga agccagaaag ctcaggaatt agtgtctcca gtggactgag 200

 tcagtgttac gggggcagcg gtttctccaa ggcccttcag gaagacgatg 250

 acctcgactt ttctctgcct gacatccgat tagaagaggg ggccatggaa 300

 gatgaagagc tgaccaacct gaactggctg cacgagagca agaacttgct 350

 gaagagcttt ggggagtcgg tcctcaggag tgtcagcccc gtccaggacc 400

 tggacgatga caccccccca tcccctgccc actctgacat gccctacgat 450

 gccaggcaga accccaactg caaacccccc tactccttca gctgcctcat 500

 atttatggcc atcgaggact ctccaaccaa gcgcctgcca gtgaaggata 550

 tctacaactg gatcttggaa cattttccgt attttgcaaa tgcacctact 600

 gggtggaaaa actcagtgag acacaattta tcattgaata agtgttttaa 650

 gaaagtggac aaagagagga gtcagagtat tgggaaaggg tcgttgtggt 700

 gcatagaccc agagtataga caaaatctaa ttcaggcttt gaaaaagaca 750

 ccttatcacc cacacccaca cgtgttcaat acacctccca cctgtcctca 800

 ggcatatcaa agcacatcag gtccacccat ctggccgggc agtaccttct 850

 tcaagagaaa tggagccctt ctccaagatc ctgacattga tgctgccagt 900

 gccatgatgc ttttgaatac tccccctgag atacaagcag gttttcctcc 950

 aggagtgatc caaaatggag cgcgggtcct gagccgaggg ctgtttcctg 1000

 gcgtgcggcc gctgccaatc actcccattg gggtgacagc ggccatgagg 1050

 aatggcatca ccagctgccg gatgcggact gagagtgagc catcttgtgg 1100

 ctccccagtg gtcagcggag accccaagga ggatcacaac tacagcagtg 1150

 ccaagtcctc caacgcccgg agcacctcgc ccaccagcga ctccatctcc 1200

 tcctcctcct cctcagccga cgaccactat gagtttgcca ccaaggggag 1250

 ccaggagggc agcgagggca gcgaggggag cttccggagc cacgagagcc 1300

 ccagcgacac ggaagaggac gacaggaagc acagccagaa ggagcccaag 1350

 gattctctgg gggacagcgg gtacgcatcc cagcacaaga agcgccagca 1400

 cttcgccaag gccaggaagg tccccagcga cacactgccc ctcaaaaaga 1450

 gacgcaccga aaagcccccc gagagcgatg atgaggagat gaaagaagcg 1500

 gcagggtccc tcctgcactt agcagggatc cggtcctgtt tgaataacat 1550

 caccaatcgg acggcaaagg ggcagaaaga gcaaaaggaa accacaaaaa 1600

 attaaaaaca agtcactgat ttgttttgaa cttacgacca tttggtttca 1650

 gcatgtcagg agatttctaa tgatttgtgg caatatcagc aatttttttt 1700

 cttttttctt gtttggggtt tggttttctt tcttttcttt tccttttatt 1750

 gggttttaat ttgccccctc ttctttgttt tggaccctta agaattttat 1800

 ttttaaagga gattgaagcc atagaactca tattgacact cagctgtttt 1850

 acaaaagctt ttcattatct gaagacaaaa ccgaaaaagc caaaattacc 1900

 attgcttcct ccagcttgtc agaaacctgt ggctgaatcc gcagggatgt 1950

 caacgtcaat atcacaggaa cacacattcg gcacctagaa ggcacgtggg 2000

 caaagtaatc atcgttcagg cccaaccctt aggtttaaaa agtcaggttg 2050

 tccatcccat tggggttcac tgagtgaagg cacataaagc aattgaggag 2100

 gaggaggaac ccctcgtccc cctaggagca gacccaagct tgtggcacca 2150

 ggcatctgat ggtgccagga aagccactgg aattgtcaca cggcgagcac 2200

 agagggccgg ccaccagtcc tcgatgcttc tgaaccctga accccgatga 2250

 catcttacga ggtggacgtt ggactgttca tgcgcatcgg gtgtcagtga 2300

 ctcatggaga agaaatgggg taaattttta gtgatgttgc taatcattga 2350

 attctgttct ctattaaatt aagaaaatgt tccaaaagcc ataagcctga 2400

 agattggccc tgtgcacgca cgcacacaca cacacacaca cacacacaca 2450

 cacacacaca cacgaaggag agagagagaa aactgatggg gaaaacaagc 2500

 tgtgtcttct taactgccca agtgaaaagc aaccaagtcc aggaaattac 2550

 aatagctgtt aaggaaagga aataatggta cagatctttt tctgtctatc 2600

 aaaactattt gatccaagtg aaaaaaaaaa aaaaactaga aagctacgga 2650

 acctgcaatg cggccgc 2667

<210> 1270
<211> 490
<212> PRT
<213> Homo sapien

<400> 1270
 Met Gly Pro Val Met Pro Pro Ser Lys Lys Pro Glu Ser Ser Gly
   1               5                  10                  15

 Ile Ser Val Ser Ser Gly Leu Ser Gln Cys Tyr Gly Gly Ser Gly
                  20                  25                  30

 Phe Ser Lys Ala Leu Gln Glu Asp Asp Asp Leu Asp Phe Ser Leu
                  35                  40                  45

 Pro Asp Ile Arg Leu Glu Glu Gly Ala Met Glu Asp Glu Glu Leu
                  50                  55                  60

 Thr Asn Leu Asn Trp Leu His Glu Ser Lys Asn Leu Leu Lys Ser
                  65                  70                  75

 Phe Gly Glu Ser Val Leu Arg Ser Val Ser Pro Val Gln Asp Leu
                  80                  85                  90

 Asp Asp Asp Thr Pro Pro Ser Pro Ala His Ser Asp Met Pro Tyr
                  95                 100                 105

 Asp Ala Arg Gln Asn Pro Asn Cys Lys Pro Pro Tyr Ser Phe Ser
                 110                 115                 120

 Cys Leu Ile Phe Met Ala Ile Glu Asp Ser Pro Thr Lys Arg Leu
                 125                 130                 135

 Pro Val Lys Asp Ile Tyr Asn Trp Ile Leu Glu His Phe Pro Tyr
                 140                 145                 150

 Phe Ala Asn Ala Pro Thr Gly Trp Lys Asn Ser Val Arg His Asn
                 155                 160                 165

 Leu Ser Leu Asn Lys Cys Phe Lys Lys Val Asp Lys Glu Arg Ser
                 170                 175                 180

 Gln Ser Ile Gly Lys Gly Ser Leu Trp Cys Ile Asp Pro Glu Tyr
                 185                 190                 195

 Arg Gln Asn Leu Ile Gln Ala Leu Lys Lys Thr Pro Tyr His Pro
                 200                 205                 210

 His Pro His Val Phe Asn Thr Pro Pro Thr Cys Pro Gln Ala Tyr
                 215                 220                 225

 Gln Ser Thr Ser Gly Pro Pro Ile Trp Pro Gly Ser Thr Phe Phe
                 230                 235                 240

 Lys Arg Asn Gly Ala Leu Leu Gln Asp Pro Asp Ile Asp Ala Ala
                 245                 250                 255

 Ser Ala Met Met Leu Leu Asn Thr Pro Pro Glu Ile Gln Ala Gly
                 260                 265                 270

 Phe Pro Pro Gly Val Ile Gln Asn Gly Ala Arg Val Leu Ser Arg
                 275                 280                 285

 Gly Leu Phe Pro Gly Val Arg Pro Leu Pro Ile Thr Pro Ile Gly
                 290                 295                 300

 Val Thr Ala Ala Met Arg Asn Gly Ile Thr Ser Cys Arg Met Arg
                 305                 310                 315

 Thr Glu Ser Glu Pro Ser Cys Gly Ser Pro Val Val Ser Gly Asp
                 320                 325                 330

 Pro Lys Glu Asp His Asn Tyr Ser Ser Ala Lys Ser Ser Asn Ala
                 335                 340                 345

 Arg Ser Thr Ser Pro Thr Ser Asp Ser Ile Ser Ser Ser Ser Ser
                 350                 355                 360

 Ser Ala Asp Asp His Tyr Glu Phe Ala Thr Lys Gly Ser Gln Glu
                 365                 370                 375

 Gly Ser Glu Gly Ser Glu Gly Ser Phe Arg Ser His Glu Ser Pro
                 380                 385                 390

 Ser Asp Thr Glu Glu Asp Asp Arg Lys His Ser Gln Lys Glu Pro
                 395                 400                 405

 Lys Asp Ser Leu Gly Asp Ser Gly Tyr Ala Ser Gln His Lys Lys
                 410                 415                 420

 Arg Gln His Phe Ala Lys Ala Arg Lys Val Pro Ser Asp Thr Leu
                 425                 430                 435

 Pro Leu Lys Lys Arg Arg Thr Glu Lys Pro Pro Glu Ser Asp Asp
                 440                 445                 450

 Glu Glu Met Lys Glu Ala Ala Gly Ser Leu Leu His Leu Ala Gly
                 455                 460                 465

 Ile Arg Ser Cys Leu Asn Asn Ile Thr Asn Arg Thr Ala Lys Gly
                 470                 475                 480

 Gln Lys Glu Gln Lys Glu Thr Thr Lys Asn
                 485                 490

<210> 1271
<211> 2254
<212> DNA
<213> Homo sapien

<400> 1271
 gggaattctg aaagccgctg gcggaccgcg cgcagcggcc agagaccgag 50

 ccctaaggag agtgcggcgc ttcccgaggc gtgcagctgg gaactgcaac 100

 tcatctgggt tgtgcgcaga aggctggggc aagcgagtag agaagtggag 150

 cgtaagccag gggcgttggg ggccgtgcgg gtcgggcgcg tgccacgccc 200

 gcggggtgaa gtcggagcgc ggggcctgct ggagagagga gcgctgcgga 250

 ccgagtaatg gcaatgcaga tgcagcttga agcaaatgca gatacttcag 300

 tggaagaaga aagctttggc ccacaaccca tttcacggtt agagcagtgt 350

 ggcataaatg ccaacgatgt gaagaaattg gaagaagctg gattccatac 400

 tgtggaggct gttgcctatg cgccaaagaa ggagctaata aatattaagg 450

 gaattagtga agccaaagct gataaaattc tggctgaggc agctaaatta 500

 gttccaatgg gtttcaccac tgcaactgaa ttccaccaaa ggcggtcaga 550

 gatcatacag attactactg gctccaaaga gcttgacaaa ctacttcaag 600

 gtggaattga gactggatct atcacagaaa tgtttggaga attccgaact 650

 gggaagaccc agatctgtca tacgctagct gtcacctgcc agcttcccat 700

 tgaccggggt ggaggtgaag gaaaggccat gtacattgac actgagggta 750

 cctttaggcc agaacggctg ctggcagtgg ctgagaggta tggtctctct 800

 ggcagtgatg tcctggataa tgtagcatat gctcgagcgt tcaacacaga 850

 ccaccagacc cagctccttt atcaagcatc agccatgatg gtagaatcta 900

 ggtatgcact gcttattgta gacagtgcca ccgcccttta cagaacagac 950

 tactcgggtc gaggtgagct ttcagccagg cagatgcact tggccaggtt 1000

 tctgcggatg cttctgcgac tcgctgatga gtttggtgta gcagtggtaa 1050

 tcactaatca ggtggtagct caagtggatg gagcagcgat gtttgctgct 1100

 gatcccaaaa aacctattgg aggaaatatc atcgcccatg catcaacaac 1150

 cagattgtat ctgaggaaag gaagagggga aaccagaatc tgcaaaatct 1200

 acgactctcc ctgtcttcct gaagctgaag ctatgttcgc cattaatgca 1250

 gatggagtgg gagatgccaa agactgaatc attgggtttt tcctctgtta 1300

 aaaaccttaa gtgctgcagc ctaatgagag tgcactgctc cctggggttc 1350

 tctacaggcc tcttcctgtt gtgactgcca ggataaagct tccgggaaaa 1400

 cagctattat atcagctttt ctgatggtat aaacaggaga caggtcagta 1450

 gtcacaaact gatctaaaat gtttattcct tctgtagtgt attaatctct 1500

 gtgtgttttc tttggttttg gaggaggggt atgaagtatc tttgacatgg 1550

 tgccttagga atgacttggg tttaacaagc tgtctactgg acaatcttat 1600

 gtttccaaga gaactaaagc tggagagacc tgacccttct ctcacttcta 1650

 aattaatggt aaaataaaat gcctcagcta tgtagcaaag ggaatgggtc 1700

 tgcacagatt ctttttttct gtcagtaaaa ctctcaagca ggtttttaag 1750

 ttgtctgtct gaatgatctt gtgtaagggt ttggttatgg agtcttgtgc 1800

 caaacctact aggccattag cccttcacca tctacctgct tggtctttca 1850

 ttgctaagac taactcaaga taatcctaga gtcttaaagc atttcaggcc 1900

 agtgtggtgt cttgcgcctg tactcccagc actttgggag gccgaggcag 1950

 gtggatcgct tgagccagga gttttaagtc cagcttggcc aagatggtga 2000

 aatcccatct ctacaaaaaa tgcagaactt aatctggaca cactgttaca 2050

 cgtgcctgta gtcccagcta ctctatagcc tgaggtggga gaatcactta 2100

 agcctggaag gtggaagttg cagtgagtcg agattgcact gctgcattcc 2150

 agccagggtg acagagtgag accatgtttc aaacaagaaa catttcagag 2200

 ggcaagtaaa cagatttgat tgtgaggctt ctaataaagt agttattagt 2250

 agtg 2254

<210> 1272
<211> 339
<212> PRT
<213> Homo sapien

<400> 1272
 Met Ala Met Gln Met Gln Leu Glu Ala Asn Ala Asp Thr Ser Val
   1               5                  10                  15

 Glu Glu Glu Ser Phe Gly Pro Gln Pro Ile Ser Arg Leu Glu Gln
                  20                  25                  30

 Cys Gly Ile Asn Ala Asn Asp Val Lys Lys Leu Glu Glu Ala Gly
                  35                  40                  45

 Phe His Thr Val Glu Ala Val Ala Tyr Ala Pro Lys Lys Glu Leu
                  50                  55                  60

 Ile Asn Ile Lys Gly Ile Ser Glu Ala Lys Ala Asp Lys Ile Leu
                  65                  70                  75

 Ala Glu Ala Ala Lys Leu Val Pro Met Gly Phe Thr Thr Ala Thr
                  80                  85                  90

 Glu Phe His Gln Arg Arg Ser Glu Ile Ile Gln Ile Thr Thr Gly
                  95                 100                 105

 Ser Lys Glu Leu Asp Lys Leu Leu Gln Gly Gly Ile Glu Thr Gly
                 110                 115                 120

 Ser Ile Thr Glu Met Phe Gly Glu Phe Arg Thr Gly Lys Thr Gln
                 125                 130                 135

 Ile Cys His Thr Leu Ala Val Thr Cys Gln Leu Pro Ile Asp Arg
                 140                 145                 150

 Gly Gly Gly Glu Gly Lys Ala Met Tyr Ile Asp Thr Glu Gly Thr
                 155                 160                 165

 Phe Arg Pro Glu Arg Leu Leu Ala Val Ala Glu Arg Tyr Gly Leu
                 170                 175                 180

 Ser Gly Ser Asp Val Leu Asp Asn Val Ala Tyr Ala Arg Ala Phe
                 185                 190                 195

 Asn Thr Asp His Gln Thr Gln Leu Leu Tyr Gln Ala Ser Ala Met
                 200                 205                 210

 Met Val Glu Ser Arg Tyr Ala Leu Leu Ile Val Asp Ser Ala Thr
                 215                 220                 225

 Ala Leu Tyr Arg Thr Asp Tyr Ser Gly Arg Gly Glu Leu Ser Ala
                 230                 235                 240

 Arg Gln Met His Leu Ala Arg Phe Leu Arg Met Leu Leu Arg Leu
                 245                 250                 255

 Ala Asp Glu Phe Gly Val Ala Val Val Ile Thr Asn Gln Val Val
                 260                 265                 270

 Ala Gln Val Asp Gly Ala Ala Met Phe Ala Ala Asp Pro Lys Lys
                 275                 280                 285

 Pro Ile Gly Gly Asn Ile Ile Ala His Ala Ser Thr Thr Arg Leu
                 290                 295                 300

 Tyr Leu Arg Lys Gly Arg Gly Glu Thr Arg Ile Cys Lys Ile Tyr
                 305                 310                 315

 Asp Ser Pro Cys Leu Pro Glu Ala Glu Ala Met Phe Ala Ile Asn
                 320                 325                 330

 Ala Asp Gly Val Gly Asp Ala Lys Asp
                 335

<210> 1273
<211> 2748
<212> DNA
<213> Homo sapien

<400> 1273
 agcgggtgcg gggcgggacc ggcccggcct atatattggg ttggcgccgg 50

 cgccagctga gccgagcggt agctggtctg gcgaggtttt atacacctga 100

 aagaagagaa tgtcaagacg aagtagccgt ttacaagcta agcagcagcc 150

 ccagcccagc cagacggaat ccccccaaga agcccagata atccaggcca 200

 agaagaggaa aactacccag gatgtcaaaa aaagaagaga ggaggtcacc 250

 aagaaacatc agtatgaaat taggaattgt tggccacctg tattatctgg 300

 ggggatcagt ccttgcatta tcattgaaac acctcacaaa gaaataggaa 350

 caagtgattt ctccagattt acaaattaca gatttaaaaa tctttttatt 400

 aatccttcac ctttgcctga tttaagctgg ggatgttcaa aagaagtctg 450

 gctaaacatg ttaaaaaagg agagcagata tgttcatgac aaacattttg 500

 aagttctgca ttctgacttg gaaccacaga tgaggtccat acttctagac 550

 tggcttttag aggtatgtga agtatacaca cttcataggg aaacatttta 600

 tcttgcacaa gacttttttg atagatttat gttgacacaa aaggatataa 650

 ataaaaatat gcttcaactc attggaatta cctcattatt cattgcttcc 700

 aaacttgagg aaatctatgc tcctaaactc caagagtttg cttacgtcac 750

 tgatggtgct tgcagtgaag aggatatctt aaggatggaa ctcattatat 800

 taaaggcttt aaaatgggaa ctttgtcctg taacaatcat ctcctggcta 850

 aatctctttc tccaagttga tgctcttaaa gatgctccta aagttcttct 900

 acctcagtat tctcaggaaa cattcattca aatagctcag cttttagatc 950

 tgtgtattct agccattgat tcattagagt tccagtacag aatactgact 1000

 gctgctgcct tgtgccattt tacctccatt gaagtggtta agaaagcctc 1050

 aggtttggag tgggacagta tttcagaatg tgtagattgg atggtacctt 1100

 ttgtcaatgt agtaaaaagt actagtccag tgaagctgaa gacttttaag 1150

 aagattccta tggaagacag acataatatc cagacacata caaactattt 1200

 ggctatgctg gaggaagtaa attacataaa caccttcaga aaagggggac 1250

 agttgtcacc agtgtgcaat ggaggcatta tgacaccacc gaagagcact 1300

 gaaaaaccac caggaaaaca ctaaagaaga taactaagca aacaagttgg 1350

 aattcaccaa gattgggtag aactggtatc actgaactac taaagtttta 1400

 cagaaagtag tgctgtgatt gattgcccta gccaattcac aagttacact 1450

 gccattctga ttttaaaact tacaattggc actaaagaat acatttaatt 1500

 atttcctatg ttagctgtta aagaaacagc aggacttgtt tacaaagatg 1550

 tcttcattcc caaggttact ggatagaagc caaccacagt ctataccata 1600

 gcaatgtttt tcctttaatc cagtgttact gtgtttatct tgataaacta 1650

 ggaattttgt cactggagtt ttggactgga taagtgctac cttaaagggt 1700

 atactaagtg atacagtact ttgaatctag ttgttagatt ctcaaaattc 1750

 ctacactctt gactagtgca atttggttct tgaaaattaa atttaaactt 1800

 gtttacaaag gtttagtttt gtaataaggt gactaattta tctatagctg 1850

 ctatagcaag ctattataaa acttgaattt ctacaaatgg tgaaatttaa 1900

 tgttttttaa actagtttat ttgccttgcc ataacacatt ttttaactaa 1950

 taaggcttag atgaacatgg tgttcaacct gtgctctaaa cagtgggagt 2000

 accaaagaaa ttataaacaa gataaatgct gtggctcctt cctaactggg 2050

 gctttcttga catgtaggtt gcttggtaat aacctttttg tatatcacaa 2100

 tttgggtgaa aaacttaagt accctttcaa actatttata tgaggaagtc 2150

 actttactac tctaagatat ccctaaggaa tttttttttt taatttagtg 2200

 tgactaaggc tttatttatg tttgtgaaac tgttaaggtc ctttctaaat 2250

 tcctccattg tgagataagg acagtgtcaa agtgataaag cttaacactt 2300

 gacctaaact tctattttct taaggaagaa gagtattaaa tatatactga 2350

 ctcctagaaa tctatttatt aaaaaaagac atgaaaactt gctgtacata 2400

 ggctagctat ttctaaatat tttaaattag cttttctaaa aaaaaaatcc 2450

 agcctcataa agtagattag aaaactagat tgctagttta ttttgttatc 2500

 agatatgtga atctcttctc cctttgaaga aactatacat ttattgttac 2550

 ggtatgaagt cttctgtata gtttgttttt aaactaatat ttgtttcagt 2600

 attttgtctg aaaagaaaac accactaatt gtgtacatat gtattatata 2650

 aacttaacct tttaatactg tttattttta gcccattgtt taaaaaataa 2700

 aagttaaaaa aatttaactg cttaaaagta aaaaaaaaaa aaaaaaaa 2748

<210> 1274
<211> 404
<212> PRT
<213> Homo sapien

<400> 1274
 Met Ser Arg Arg Ser Ser Arg Leu Gln Ala Lys Gln Gln Pro Gln
   1               5                  10                  15

 Pro Ser Gln Thr Glu Ser Pro Gln Glu Ala Gln Ile Ile Gln Ala
                  20                  25                  30

 Lys Lys Arg Lys Thr Thr Gln Asp Val Lys Lys Arg Arg Glu Glu
                  35                  40                  45

 Val Thr Lys Lys His Gln Tyr Glu Ile Arg Asn Cys Trp Pro Pro
                  50                  55                  60

 Val Leu Ser Gly Gly Ile Ser Pro Cys Ile Ile Ile Glu Thr Pro
                  65                  70                  75

 His Lys Glu Ile Gly Thr Ser Asp Phe Ser Arg Phe Thr Asn Tyr
                  80                  85                  90

 Arg Phe Lys Asn Leu Phe Ile Asn Pro Ser Pro Leu Pro Asp Leu
                  95                 100                 105

 Ser Trp Gly Cys Ser Lys Glu Val Trp Leu Asn Met Leu Lys Lys
                 110                 115                 120

 Glu Ser Arg Tyr Val His Asp Lys His Phe Glu Val Leu His Ser
                 125                 130                 135

 Asp Leu Glu Pro Gln Met Arg Ser Ile Leu Leu Asp Trp Leu Leu
                 140                 145                 150

 Glu Val Cys Glu Val Tyr Thr Leu His Arg Glu Thr Phe Tyr Leu
                 155                 160                 165

 Ala Gln Asp Phe Phe Asp Arg Phe Met Leu Thr Gln Lys Asp Ile
                 170                 175                 180

 Asn Lys Asn Met Leu Gln Leu Ile Gly Ile Thr Ser Leu Phe Ile
                 185                 190                 195

 Ala Ser Lys Leu Glu Glu Ile Tyr Ala Pro Lys Leu Gln Glu Phe
                 200                 205                 210

 Ala Tyr Val Thr Asp Gly Ala Cys Ser Glu Glu Asp Ile Leu Arg
                 215                 220                 225

 Met Glu Leu Ile Ile Leu Lys Ala Leu Lys Trp Glu Leu Cys Pro
                 230                 235                 240

 Val Thr Ile Ile Ser Trp Leu Asn Leu Phe Leu Gln Val Asp Ala
                 245                 250                 255

 Leu Lys Asp Ala Pro Lys Val Leu Leu Pro Gln Tyr Ser Gln Glu
                 260                 265                 270

 Thr Phe Ile Gln Ile Ala Gln Leu Leu Asp Leu Cys Ile Leu Ala
                 275                 280                 285

 Ile Asp Ser Leu Glu Phe Gln Tyr Arg Ile Leu Thr Ala Ala Ala
                 290                 295                 300

 Leu Cys His Phe Thr Ser Ile Glu Val Val Lys Lys Ala Ser Gly
                 305                 310                 315

 Leu Glu Trp Asp Ser Ile Ser Glu Cys Val Asp Trp Met Val Pro
                 320                 325                 330

 Phe Val Asn Val Val Lys Ser Thr Ser Pro Val Lys Leu Lys Thr
                 335                 340                 345

 Phe Lys Lys Ile Pro Met Glu Asp Arg His Asn Ile Gln Thr His
                 350                 355                 360

 Thr Asn Tyr Leu Ala Met Leu Glu Glu Val Asn Tyr Ile Asn Thr
                 365                 370                 375

 Phe Arg Lys Gly Gly Gln Leu Ser Pro Val Cys Asn Gly Gly Ile
                 380                 385                 390

 Met Thr Pro Pro Lys Ser Thr Glu Lys Pro Pro Gly Lys His
                 395                 400

<210> 1275
<211> 2348
<212> DNA
<213> Homo sapien

<400> 1275
 cctttctgtc ctggttccct gaagcatcga gagggaaccg cggccggcag 50

 gccggaccgc tccggagagg aggcagcggc agtttgagcc cctgtaaatg 100

 ttatatgtgt actttttttt actatgtggc gtcgaagcct gtggacattt 150

 tcgcggtccg ggtccctgcg gcggacgggt cggatcgtgc tcgtggccag 200

 ggcgcagtca ggtgtcgcgt ggtcctgatc taggaagaga ctgcggcctt 250

 atcaccgtct cggtgtctgc tttcaccttc aactgccccc ctcctcacct 300

 ggaccgctca ccctcctcct cccctctcac cccgccatcc ccaccagtcc 350

 ccacctgtct ctgtagactg caagactcat caagtgactt gctgagcaaa 400

 ccctgccgag aagagatttt cttcaatcac atctgaataa atcacttgaa 450

 gaaagcttat agcttcattg caccatgtgt ggcatttggg cgctgtttgg 500

 cagtgatgat tgcctttctg ttcagtgtct gagtgctatg aagattgcac 550

 acagaggtcc agatgcattc cgttttgaga atgtcaatgg atacaccaac 600

 tgctgctttg gatttcaccg gttggcggta gttgacccgc tgtttggaat 650

 gcagccaatt cgagtgaaga aatatccgta tttgtggctc tgttacaatg 700

 gtgaaatcta caaccataag aagatgcaac agcattttga atttgaatac 750

 cagaccaaag tggatggtga gataatcctt catctttatg acaaaggagg 800

 aattgagcaa acaatttgta tgttggatgg tgtgtttgca tttgttttac 850

 tggatactgc caataagaaa gtgttcctgg gtagagatac atatggagtc 900

 agacctttgt ttaaagcaat gacagaagat ggatttttgg ctgtatgttc 950

 agaagctaaa ggtcttgtta cattgaagca ctccgcgact ccctttttaa 1000

 aagtggagcc ttttcttcct ggacactatg aagttttgga tttaaagcca 1050

 aatggcaaag ttgcatccgt ggaaatggtt aaatatcatc actgtcggga 1100

 tgaacccctg cacgccctct atgacaatgt ggagaaactc tttccaggtt 1150

 ttgagataga aactgtgaag aacaacctca ggatcctttt taataatgct 1200

 gtaaagaaac gtttgatgac agacagaagg attggctgcc ttttatcagg 1250

 gggcttggac tccagcttgg ttgctgccac tctgttgaag cagctgaaag 1300

 aagcccaagt acagtatcct ctccagacat ttgcaattgg catggaagac 1350

 agccccgatt tactggctgc tagaaaggtg gcagatcata ttggaagtga 1400

 acattatgaa gtccttttta actctgagga aggcattcag gctctggatg 1450

 aagtcatatt ttccttggaa acttatgaca ttacaacagt tcgtgcttca 1500

 gtaggtatgt atttaatttc caagtatatt cggaagaaca cagatagcgt 1550

 ggtgatcttc tctggagaag gatcagatga acttacgcag ggttacatat 1600

 attttcacaa ggctccttct cctgaaaaag ccgaggagga gagtgagagg 1650

 cttctgaggg aactctattt gtttgatgtt ctccgcgcag atcgaactac 1700

 tgctgcccat ggtcttgaac tgagagtccc atttctagat catcgatttt 1750

 cttcctatta cttgtctctg ccaccagaaa tgagaattcc aaagaatggg 1800

 atagaaaaac atctcctgag agagacgttt gaggattcca atctgatacc 1850

 caaagagatt ctctggcgac caaaagaagc cttcagtgat ggaataactt 1900

 cagttaagaa ttcctggttt aagattttac aggaatacgt tgaacatcag 1950

 gttgatgatg caatgatggc aaatgcagcc cagaaatttc ccttcaatac 2000

 tcctaaaacc aaagaaggat attactaccg tcaagtcttt gaacgccatt 2050

 acccaggccg ggctgactgg ctgagccatt actggatgcc caagtggatc 2100

 aatgccactg acccttctgc ccgcacgctg acccactaca agtcagctgt 2150

 caaagcttag gtggtcttta tgctgtaatg tgaaagcaaa tatttcttcg 2200

 tgttggatgg ggactgtggg tagatagggg aacaatgaga gtcaactcag 2250

 gctaacttgg gtgtgaaaaa aataaaagtc ctaaatctaa aaaaaaaaaa 2300

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 2348

<210> 1276
<211> 561
<212> PRT
<213> Homo sapien

<400> 1276
 Met Cys Gly Ile Trp Ala Leu Phe Gly Ser Asp Asp Cys Leu Ser
   1               5                  10                  15

 Val Gln Cys Leu Ser Ala Met Lys Ile Ala His Arg Gly Pro Asp
                  20                  25                  30

 Ala Phe Arg Phe Glu Asn Val Asn Gly Tyr Thr Asn Cys Cys Phe
                  35                  40                  45

 Gly Phe His Arg Leu Ala Val Val Asp Pro Leu Phe Gly Met Gln
                  50                  55                  60

 Pro Ile Arg Val Lys Lys Tyr Pro Tyr Leu Trp Leu Cys Tyr Asn
                  65                  70                  75

 Gly Glu Ile Tyr Asn His Lys Lys Met Gln Gln His Phe Glu Phe
                  80                  85                  90

 Glu Tyr Gln Thr Lys Val Asp Gly Glu Ile Ile Leu His Leu Tyr
                  95                 100                 105

 Asp Lys Gly Gly Ile Glu Gln Thr Ile Cys Met Leu Asp Gly Val
                 110                 115                 120

 Phe Ala Phe Val Leu Leu Asp Thr Ala Asn Lys Lys Val Phe Leu
                 125                 130                 135

 Gly Arg Asp Thr Tyr Gly Val Arg Pro Leu Phe Lys Ala Met Thr
                 140                 145                 150

 Glu Asp Gly Phe Leu Ala Val Cys Ser Glu Ala Lys Gly Leu Val
                 155                 160                 165

 Thr Leu Lys His Ser Ala Thr Pro Phe Leu Lys Val Glu Pro Phe
                 170                 175                 180

 Leu Pro Gly His Tyr Glu Val Leu Asp Leu Lys Pro Asn Gly Lys
                 185                 190                 195

 Val Ala Ser Val Glu Met Val Lys Tyr His His Cys Arg Asp Glu
                 200                 205                 210

 Pro Leu His Ala Leu Tyr Asp Asn Val Glu Lys Leu Phe Pro Gly
                 215                 220                 225

 Phe Glu Ile Glu Thr Val Lys Asn Asn Leu Arg Ile Leu Phe Asn
                 230                 235                 240

 Asn Ala Val Lys Lys Arg Leu Met Thr Asp Arg Arg Ile Gly Cys
                 245                 250                 255

 Leu Leu Ser Gly Gly Leu Asp Ser Ser Leu Val Ala Ala Thr Leu
                 260                 265                 270

 Leu Lys Gln Leu Lys Glu Ala Gln Val Gln Tyr Pro Leu Gln Thr
                 275                 280                 285

 Phe Ala Ile Gly Met Glu Asp Ser Pro Asp Leu Leu Ala Ala Arg
                 290                 295                 300

 Lys Val Ala Asp His Ile Gly Ser Glu His Tyr Glu Val Leu Phe
                 305                 310                 315

 Asn Ser Glu Glu Gly Ile Gln Ala Leu Asp Glu Val Ile Phe Ser
                 320                 325                 330

 Leu Glu Thr Tyr Asp Ile Thr Thr Val Arg Ala Ser Val Gly Met
                 335                 340                 345

 Tyr Leu Ile Ser Lys Tyr Ile Arg Lys Asn Thr Asp Ser Val Val
                 350                 355                 360

 Ile Phe Ser Gly Glu Gly Ser Asp Glu Leu Thr Gln Gly Tyr Ile
                 365                 370                 375

 Tyr Phe His Lys Ala Pro Ser Pro Glu Lys Ala Glu Glu Glu Ser
                 380                 385                 390

 Glu Arg Leu Leu Arg Glu Leu Tyr Leu Phe Asp Val Leu Arg Ala
                 395                 400                 405

 Asp Arg Thr Thr Ala Ala His Gly Leu Glu Leu Arg Val Pro Phe
                 410                 415                 420

 Leu Asp His Arg Phe Ser Ser Tyr Tyr Leu Ser Leu Pro Pro Glu
                 425                 430                 435

 Met Arg Ile Pro Lys Asn Gly Ile Glu Lys His Leu Leu Arg Glu
                 440                 445                 450

 Thr Phe Glu Asp Ser Asn Leu Ile Pro Lys Glu Ile Leu Trp Arg
                 455                 460                 465

 Pro Lys Glu Ala Phe Ser Asp Gly Ile Thr Ser Val Lys Asn Ser
                 470                 475                 480

 Trp Phe Lys Ile Leu Gln Glu Tyr Val Glu His Gln Val Asp Asp
                 485                 490                 495

 Ala Met Met Ala Asn Ala Ala Gln Lys Phe Pro Phe Asn Thr Pro
                 500                 505                 510

 Lys Thr Lys Glu Gly Tyr Tyr Tyr Arg Gln Val Phe Glu Arg His
                 515                 520                 525

 Tyr Pro Gly Arg Ala Asp Trp Leu Ser His Tyr Trp Met Pro Lys
                 530                 535                 540

 Trp Ile Asn Ala Thr Asp Pro Ser Ala Arg Thr Leu Thr His Tyr
                 545                 550                 555

 Lys Ser Ala Val Lys Ala
                 560

<210> 1277
<211> 839
<212> DNA
<213> Homo sapien

<400> 1277
 aagccacagg ctccctggct ggcgtcagct aaagtggctg ttgggtgtcc 50

 gcaggcttct gcctggccgc cgccgcctat aagctaccag gaggagcttt 100

 acgacttccc gtcctgcggg aagtggcggg cacgatcgca aggtagcgca 150

 gaagcttctc aatggccagc gccagctgca gccccggcgg cgcactcgcc 200

 tcacctgagc ctgggaggaa aattcttcca aggatgatct cccactcaga 250

 gctgaggaag cttttctact cagcagatgc tgtgtgtttt gatgttgaca 300

 gcacggtcat cagtgaagaa ggaatcggat gctttcattg gatttggagg 350

 aaatgtgatc aggcaacaag tcaaggataa cgccaaatgg tatatcactg 400

 attttgtaga gctgctggga gaaccggaag aataacatcc attgtcatac 450

 agctccaaac aacttcagat gaatttttac aagttacaca gattgatact 500

 gtttgcttac aattgcctat tacaacttgc tataaaaagt tggtacagat 550

 gatctgcact gtcaagtaaa ctacagttag gaatcctcaa agattggttt 600

 gtttgttttt aactgtagtt ccagtattat atgatcacta tcgatttcct 650

 ggagagtttt gtaatctgaa ttctttatgt atattcctag ctatatttca 700

 tacaaagtgt tttaagagtg gagagtcaat taaacacctt tactcttagg 750

 aatatagatt cggcagcctt cagtgaatat tggttttttt ccctttggta 800

 tgtcaataaa agtttatcca tgtgtcagaa aaaaaaaaa 839

<210> 1278
<211> 72
<212> PRT
<213> Homo sapien

<400> 1278
 Met Ala Ser Ala Ser Cys Ser Pro Gly Gly Ala Leu Ala Ser Pro
   1               5                  10                  15

 Glu Pro Gly Arg Lys Ile Leu Pro Arg Met Ile Ser His Ser Glu
                  20                  25                  30

 Leu Arg Lys Leu Phe Tyr Ser Ala Asp Ala Val Cys Phe Asp Val
                  35                  40                  45

 Asp Ser Thr Val Ile Ser Glu Glu Gly Ile Gly Cys Phe His Trp
                  50                  55                  60

 Ile Trp Arg Lys Cys Asp Gln Ala Thr Ser Gln Gly
                  65                  70

<210> 1279
<211> 5084
<212> DNA
<213> Homo sapien

<400> 1279
 gatcccatcg cagctaccgc gatgagaggc gctcgcggcg cctgggattt 50

 tctctgcgtt ctgctcctac tgcttcgcgt ccagacaggc tcttctcaac 100

 catctgtgag tccaggggaa ccgtctccac catccatcca tccaggaaaa 150

 tcagacttaa tagtccgcgt gggcgacgag attaggctgt tatgcactga 200

 tccgggcttt gtcaaatgga cttttgagat cctggatgaa acgaatgaga 250

 ataagcagaa tgaatggatc acggaaaagg cagaagccac caacaccggc 300

 aaatacacgt gcaccaacaa acacggctta agcaattcca tttatgtgtt 350

 tgttagagat cctgccaagc ttttccttgt tgaccgctcc ttgtatggga 400

 aagaagacaa cgacacgctg gtccgctgtc ctctcacaga cccagaagtg 450

 accaattatt ccctcaaggg gtgccagggg aagcctcttc ccaaggactt 500

 gaggtttatt cctgacccca aggcgggcat catgatcaaa agtgtgaaac 550

 gcgcctacca tcggctctgt ctgcattgtt ctgtggacca ggagggcaag 600

 tcagtgctgt cggaaaaatt catcctgaaa gtgaggccag ccttcaaagc 650

 tgtgcctgtt gtgtctgtgt ccaaagcaag ctatcttctt agggaagggg 700

 aagaattcac agtgacgtgc acaataaaag atgtgtctag ttctgtgtac 750

 tcaacgtgga aaagagaaaa cagtcagact aaactacagg agaaatataa 800

 tagctggcat cacggtgact tcaattatga acgtcaggca acgttgacta 850

 tcagttcagc gagagttaat gattctggag tgttcatgtg ttatgccaat 900

 aatacttttg gatcagcaaa tgtcacaaca accttggaag tagtagataa 950

 aggattcatt aatatcttcc ccatgataaa cactacagta tttgtaaacg 1000

 atggagaaaa tgtagatttg attgttgaat atgaagcatt ccccaaacct 1050

 gaacaccagc agtggatcta tatgaacaga accttcactg ataaatggga 1100

 agattatccc aagtctgaga atgaaagtaa tatcagatac gtaagtgaac 1150

 ttcatctaac gagattaaaa ggcaccgaag gaggcactta cacattccta 1200

 gtgtccaatt ctgacgtcaa tgctgccata gcatttaatg tttatgtgaa 1250

 tacaaaacca gaaatcctga cttacgacag gctcgtgaat ggcatgctcc 1300

 aatgtgtggc agcaggattc ccagagccca caatagattg gtatttttgt 1350

 ccaggaactg agcagagatg ctctgcttct gtactgccag tggatgtgca 1400

 gacactaaac tcatctgggc caccgtttgg aaagctagtg gttcagagtt 1450

 ctatagattc tagtgcattc aagcacaatg gcacggttga atgtaaggct 1500

 tacaacgatg tgggcaagac ttctgcctat tttaactttg catttaaagg 1550

 taacaacaaa gagcaaatcc atccccacac cctgttcact cctttgctga 1600

 ttggtttcgt aatcgtagct ggcatgatgt gcattattgt gatgattctg 1650

 acctacaaat atttacagaa acccatgtat gaagtacagt ggaaggttgt 1700

 tgaggagata aatggaaaca attatgttta catagaccca acacaacttc 1750

 cttatgatca caaatgggag tttcccagaa acaggctgag ttttgggaaa 1800

 accctgggtg ctggagcttt cgggaaggtt gttgaggcaa ctgcttatgg 1850

 cttaattaag tcagatgcgg ccatgactgt cgctgtaaag atgctcaagc 1900

 cgagtgccca tttgacagaa cgggaagccc tcatgtctga actcaaagtc 1950

 ctgagttacc ttggtaatca catgaatatt gtgaatctac ttggagcctg 2000

 caccattgga gggcccaccc tggtcattac agaatattgt tgctatggtg 2050

 atcttttgaa ttttttgaga agaaaacgtg attcatttat ttgttcaaag 2100

 caggaagatc atgcagaagc tgcactttat aagaatcttc tgcattcaaa 2150

 ggagtcttcc tgcagcgata gtactaatga gtacatggac atgaaacctg 2200

 gagtttctta tgttgtccca accaaggccg acaaaaggag atctgtgaga 2250

 ataggctcat acatagaaag agatgtgact cccgccatca tggaggatga 2300

 cgagttggcc ctagacttag aagacttgct gagcttttct taccaggtgg 2350

 caaagggcat ggctttcctc gcctccaaga attgtattca cagagacttg 2400

 gcagccagaa atatcctcct tactcatggt cggatcacaa agatttgtga 2450

 ttttggtcta gccagagaca tcaagaatga ttctaattat gtggttaaag 2500

 gaaacgctcg actacctgtg aagtggatgg cacctgaaag cattttcaac 2550

 tgtgtataca cgtttgaaag tgacgtctgg tcctatggga tttttctttg 2600

 ggagctgttc tctttaggaa gcagccccta tcctggaatg ccggtcgatt 2650

 ctaagttcta caagatgatc aaggaaggct tccggatgct cagccctgaa 2700

 cacgcacctg ctgaaatgta tgacataatg aagacttgct gggatgcaga 2750

 tcccctaaaa agaccaacat tcaagcaaat tgttcagcta attgagaagc 2800

 agatttcaga gagcaccaat catatttact ccaacttagc aaactgcagc 2850

 cccaaccgac agaagcccgt ggtagaccat tctgtgcgga tcaattctgt 2900

 cggcagcacc gcttcctcct cccagcctct gcttgtgcac gacgatgtct 2950

 gagcagaatc agtgtttggg tcacccctcc aggaatgatc tcttcttttg 3000

 gcttccatga tggttatttt cttttctttc aacttgcatc caactccagg 3050

 atagtgggca ccccactgca atcctgtctt tctgagcaca ctttagtggc 3100

 cgatgatttt tgtcatcagc caccatccta ttgcaaaggt tccaactgta 3150

 tatattccca atagcaacgt agcttctacc atgaacagaa aacattctga 3200

 tttggaaaaa gagagggagg tatggactgg gggccagagt cctttccaag 3250

 gcttctccaa ttctgcccaa aaatatggtt gatagtttac ctgaataaat 3300

 ggtagtaatc acagttggcc ttcagaacca tccatagtag tatgatgata 3350

 caagattaga agctgaaaac ctaagtcctt tatgtggaaa acagaacatc 3400

 attagaacaa aggacagagt atgaacacct gggcttaaga aatctagtat 3450

 ttcatgctgg gaatgagaca taggccatga aaaaaatgat ccccaagtgt 3500

 gaacaaaaga tgctcttctg tggaccactg catgagcttt tatactaccg 3550

 acctggtttt taaatagagt ttgctattag agcattgaat tggagagaag 3600

 gcctccctag ccagcacttg tatatacgca tctataaatt gtccgtgttc 3650

 atacatttga ggggaaaaca ccataaggtt tcgtttctgt atacaaccct 3700

 ggcattatgt ccactgtgta tagaagtaga ttaagagcca tataagtttg 3750

 aaggaaacag ttaataccat tttttaagga aacaatataa ccacaaagca 3800

 cagtttgaac aaaatctcct cttttagctg atgaacttat tctgtagatt 3850

 ctgtggaaca agcctatcag cttcagaatg gcattgtact caatggattt 3900

 gatgctgttt gacaaagtta ctgattcact gcatggctcc cacaggagtg 3950

 ggaaaacact gccatcttag tttggattct tatgtagcag gaaataaagt 4000

 ataggtttag cctccttcgc aggcatgtcc tggacaccgg gccagtatct 4050

 atatatgtgt atgtacgttt gtatgtgtgt agacaaatat ttggaggggt 4100

 atttttgccc tgagtccaag agggtccttt agtacctgaa aagtaacttg 4150

 gctttcatta ttagtactgc tcttgtttct tttcacatag ctgtctagag 4200

 tagcttacca gaagcttcca tagtggtgca gaggaagtgg aaggcatcag 4250

 tccctatgta tttgcagttc acctgcactt aaggcactct gttatttaga 4300

 ctcatcttac tgtacctgtt ccttagacct tccataatgc tactgtctca 4350

 ctgaaacatt taaattttac cctttagact gtagcctgga tattattctt 4400

 gtagtttacc tctttaaaaa caaaacaaaa caaaacaaaa aactcccctt 4450

 cctcactgcc caatataaaa ggcaaatgtg tacatggcag agtttgtgtg 4500

 ttgtcttgaa agattcaggt atgttgcctt tatggtttcc cccttctaca 4550

 tttcttagac tacatttaga gaactgtggc cgttatctgg aagtaaccat 4600

 ttgcactgga gttctatgct ctcgcacctt tccaaagtta acagattttg 4650

 gggttgtgtt gtcacccaag agattgttgt ttgccatact ttgtctgaaa 4700

 aattcctttg tgtttctatt gacttcaatg atagtaagaa aagtggttgt 4750

 tagttataga tgtctaggta cttcaggggc acttcattga gagttttgtc 4800

 ttgccatact ttgtctgaaa aattcctttg tgtttctatt gacttcaatg 4850

 atagtaagaa aagtggttgt tagttataga tgtctaggta cttcaggggc 4900

 acttcattga gagttttgtc aatgtctttt gaatattccc aagcccatga 4950

 gtccttgaaa atatttttta tatatacagt aactttatgt gtaaatacat 5000

 aagcggcgta agtttaaagg atgttggtgt tccacgtgtt ttattcctgt 5050

 atgttgtcca attgttgaca gttctgaaga attc 5084

<210> 1280
<211> 976
<212> PRT
<213> Homo sapien

<400> 1280
 Met Arg Gly Ala Arg Gly Ala Trp Asp Phe Leu Cys Val Leu Leu
   1               5                  10                  15

 Leu Leu Leu Arg Val Gln Thr Gly Ser Ser Gln Pro Ser Val Ser
                  20                  25                  30

 Pro Gly Glu Pro Ser Pro Pro Ser Ile His Pro Gly Lys Ser Asp
                  35                  40                  45

 Leu Ile Val Arg Val Gly Asp Glu Ile Arg Leu Leu Cys Thr Asp
                  50                  55                  60

 Pro Gly Phe Val Lys Trp Thr Phe Glu Ile Leu Asp Glu Thr Asn
                  65                  70                  75

 Glu Asn Lys Gln Asn Glu Trp Ile Thr Glu Lys Ala Glu Ala Thr
                  80                  85                  90

 Asn Thr Gly Lys Tyr Thr Cys Thr Asn Lys His Gly Leu Ser Asn
                  95                 100                 105

 Ser Ile Tyr Val Phe Val Arg Asp Pro Ala Lys Leu Phe Leu Val
                 110                 115                 120

 Asp Arg Ser Leu Tyr Gly Lys Glu Asp Asn Asp Thr Leu Val Arg
                 125                 130                 135

 Cys Pro Leu Thr Asp Pro Glu Val Thr Asn Tyr Ser Leu Lys Gly
                 140                 145                 150

 Cys Gln Gly Lys Pro Leu Pro Lys Asp Leu Arg Phe Ile Pro Asp
                 155                 160                 165

 Pro Lys Ala Gly Ile Met Ile Lys Ser Val Lys Arg Ala Tyr His
                 170                 175                 180

 Arg Leu Cys Leu His Cys Ser Val Asp Gln Glu Gly Lys Ser Val
                 185                 190                 195

 Leu Ser Glu Lys Phe Ile Leu Lys Val Arg Pro Ala Phe Lys Ala
                 200                 205                 210

 Val Pro Val Val Ser Val Ser Lys Ala Ser Tyr Leu Leu Arg Glu
                 215                 220                 225

 Gly Glu Glu Phe Thr Val Thr Cys Thr Ile Lys Asp Val Ser Ser
                 230                 235                 240

 Ser Val Tyr Ser Thr Trp Lys Arg Glu Asn Ser Gln Thr Lys Leu
                 245                 250                 255

 Gln Glu Lys Tyr Asn Ser Trp His His Gly Asp Phe Asn Tyr Glu
                 260                 265                 270

 Arg Gln Ala Thr Leu Thr Ile Ser Ser Ala Arg Val Asn Asp Ser
                 275                 280                 285

 Gly Val Phe Met Cys Tyr Ala Asn Asn Thr Phe Gly Ser Ala Asn
                 290                 295                 300

 Val Thr Thr Thr Leu Glu Val Val Asp Lys Gly Phe Ile Asn Ile
                 305                 310                 315

 Phe Pro Met Ile Asn Thr Thr Val Phe Val Asn Asp Gly Glu Asn
                 320                 325                 330

 Val Asp Leu Ile Val Glu Tyr Glu Ala Phe Pro Lys Pro Glu His
                 335                 340                 345

 Gln Gln Trp Ile Tyr Met Asn Arg Thr Phe Thr Asp Lys Trp Glu
                 350                 355                 360

 Asp Tyr Pro Lys Ser Glu Asn Glu Ser Asn Ile Arg Tyr Val Ser
                 365                 370                 375

 Glu Leu His Leu Thr Arg Leu Lys Gly Thr Glu Gly Gly Thr Tyr
                 380                 385                 390

 Thr Phe Leu Val Ser Asn Ser Asp Val Asn Ala Ala Ile Ala Phe
                 395                 400                 405

 Asn Val Tyr Val Asn Thr Lys Pro Glu Ile Leu Thr Tyr Asp Arg
                 410                 415                 420

 Leu Val Asn Gly Met Leu Gln Cys Val Ala Ala Gly Phe Pro Glu
                 425                 430                 435

 Pro Thr Ile Asp Trp Tyr Phe Cys Pro Gly Thr Glu Gln Arg Cys
                 440                 445                 450

 Ser Ala Ser Val Leu Pro Val Asp Val Gln Thr Leu Asn Ser Ser
                 455                 460                 465

 Gly Pro Pro Phe Gly Lys Leu Val Val Gln Ser Ser Ile Asp Ser
                 470                 475                 480

 Ser Ala Phe Lys His Asn Gly Thr Val Glu Cys Lys Ala Tyr Asn
                 485                 490                 495

 Asp Val Gly Lys Thr Ser Ala Tyr Phe Asn Phe Ala Phe Lys Gly
                 500                 505                 510

 Asn Asn Lys Glu Gln Ile His Pro His Thr Leu Phe Thr Pro Leu
                 515                 520                 525

 Leu Ile Gly Phe Val Ile Val Ala Gly Met Met Cys Ile Ile Val
                 530                 535                 540

 Met Ile Leu Thr Tyr Lys Tyr Leu Gln Lys Pro Met Tyr Glu Val
                 545                 550                 555

 Gln Trp Lys Val Val Glu Glu Ile Asn Gly Asn Asn Tyr Val Tyr
                 560                 565                 570

 Ile Asp Pro Thr Gln Leu Pro Tyr Asp His Lys Trp Glu Phe Pro
                 575                 580                 585

 Arg Asn Arg Leu Ser Phe Gly Lys Thr Leu Gly Ala Gly Ala Phe
                 590                 595                 600

 Gly Lys Val Val Glu Ala Thr Ala Tyr Gly Leu Ile Lys Ser Asp
                 605                 610                 615

 Ala Ala Met Thr Val Ala Val Lys Met Leu Lys Pro Ser Ala His
                 620                 625                 630

 Leu Thr Glu Arg Glu Ala Leu Met Ser Glu Leu Lys Val Leu Ser
                 635                 640                 645

 Tyr Leu Gly Asn His Met Asn Ile Val Asn Leu Leu Gly Ala Cys
                 650                 655                 660

 Thr Ile Gly Gly Pro Thr Leu Val Ile Thr Glu Tyr Cys Cys Tyr
                 665                 670                 675

 Gly Asp Leu Leu Asn Phe Leu Arg Arg Lys Arg Asp Ser Phe Ile
                 680                 685                 690

 Cys Ser Lys Gln Glu Asp His Ala Glu Ala Ala Leu Tyr Lys Asn
                 695                 700                 705

 Leu Leu His Ser Lys Glu Ser Ser Cys Ser Asp Ser Thr Asn Glu
                 710                 715                 720

 Tyr Met Asp Met Lys Pro Gly Val Ser Tyr Val Val Pro Thr Lys
                 725                 730                 735

 Ala Asp Lys Arg Arg Ser Val Arg Ile Gly Ser Tyr Ile Glu Arg
                 740                 745                 750

 Asp Val Thr Pro Ala Ile Met Glu Asp Asp Glu Leu Ala Leu Asp
                 755                 760                 765

 Leu Glu Asp Leu Leu Ser Phe Ser Tyr Gln Val Ala Lys Gly Met
                 770                 775                 780

 Ala Phe Leu Ala Ser Lys Asn Cys Ile His Arg Asp Leu Ala Ala
                 785                 790                 795

 Arg Asn Ile Leu Leu Thr His Gly Arg Ile Thr Lys Ile Cys Asp
                 800                 805                 810

 Phe Gly Leu Ala Arg Asp Ile Lys Asn Asp Ser Asn Tyr Val Val
                 815                 820                 825

 Lys Gly Asn Ala Arg Leu Pro Val Lys Trp Met Ala Pro Glu Ser
                 830                 835                 840

 Ile Phe Asn Cys Val Tyr Thr Phe Glu Ser Asp Val Trp Ser Tyr
                 845                 850                 855

 Gly Ile Phe Leu Trp Glu Leu Phe Ser Leu Gly Ser Ser Pro Tyr
                 860                 865                 870

 Pro Gly Met Pro Val Asp Ser Lys Phe Tyr Lys Met Ile Lys Glu
                 875                 880                 885

 Gly Phe Arg Met Leu Ser Pro Glu His Ala Pro Ala Glu Met Tyr
                 890                 895                 900

 Asp Ile Met Lys Thr Cys Trp Asp Ala Asp Pro Leu Lys Arg Pro
                 905                 910                 915

 Thr Phe Lys Gln Ile Val Gln Leu Ile Glu Lys Gln Ile Ser Glu
                 920                 925                 930

 Ser Thr Asn His Ile Tyr Ser Asn Leu Ala Asn Cys Ser Pro Asn
                 935                 940                 945

 Arg Gln Lys Pro Val Val Asp His Ser Val Arg Ile Asn Ser Val
                 950                 955                 960

 Gly Ser Thr Ala Ser Ser Ser Gln Pro Leu Leu Val His Asp Asp
                 965                 970                 975

 Val


<210> 1281
<211> 1548
<212> DNA
<213> Homo sapien

<400> 1281
 caacatggcg gccgcggtgg cggcggcacc tggggccttg ggatccctgc 50

 atgctggcgg cgcccgcctg gtggccgctt gcagtgcgtg gctctgcccg 100

 gggttgaggc tgcccggctc gttggcaggc cggcgagcgg gcccggcgat 150

 ctgggcccag ggctgggtac ctgcggccgg gggtcccgcc ccgaaaaggg 200

 gctacagctc tgagatgaag acggaggacg agctgcgggt gcggcacctg 250

 gaggaggaga accgaggaat tgtggtgctt ggaataaaca gagcttatgg 300

 caaaaattca ctcagtaaaa atcttataaa aatgctatca aaagctgtgg 350

 atgctttgaa atctgataag aaagtacgga ccataataat caggagtgaa 400

 gtcccaggga tattctgtgc tggtgctgac cttaaggaaa gagccaaaat 450

 gagttccagt gaagttggtc cttttgtctc caaaataaga gcagtgatta 500

 acgatattgc taatcttcca gtgccaacaa ttgcagcaat agatggactc 550

 gctttaggtg gtggtcttga actggcttta gcctgtgata tacgagtagc 600

 agcttcctct gcaaaaatgg gcctggttga aacaaaattg gcgattattc 650

 ctggtggagg ggggacacag cgattgccac gcgccattgg aatgtccctg 700

 gccaaggagc tcatattctc tgcgcgagtc ctcgatggca aagaagccaa 750

 agcagtgggc ttaatcagcc acgttctgga acagaaccag gagggagacg 800

 cggcctacag gaaggccttg gacctggcga gagagttttt acctcaggga 850

 cctgttgcaa tgagagtggc aaaattagca attaatcaag ggatggaggt 900

 cgatttagta acagggttag ccatagaaga agcttgttat gctcagacca 950

 ttccaacaaa agacagactt gaaggtcttc ttgcttttaa agagaaaagg 1000

 ccccctcgct ataaaggaga ataaaaggaa cagaaattct taagatgcca 1050

 atgtaataaa tgtacttcct ggaagtgtct ttcggatcca ctatatgcct 1100

 cagcacatgg aaccttaatg accaaagtga agagcagatt attcatacgg 1150

 tgtaataagc gtctggaatg gacccatccg tgtacttcat tcaaatgtgt 1200

 aaatgtcata ttcattcaga tttataaagc tagtagtgta tagtcagaaa 1250

 cagaatcaaa gttagatata catttttaaa tatttactgc atatgaggct 1300

 ttctgttaat tttttaatgt gaataattta tatattgcac attctaggaa 1350

 taatattgat tgtatgtcta ctgtgctgca ttaagaaaat aaaatttcta 1400

 tataccaaaa atgtgaagtt ataccaaata aagtttctaa gtgattaatg 1450

 catacgaaca gctacatata catatatcta aacctgaaaa atgaattgat 1500

 attctgagtg aaaactacct aatataaata aaattagtga aaagaaaa 1548

<210> 1282
<211> 339
<212> PRT
<213> Homo sapien

<400> 1282
 Met Ala Ala Ala Val Ala Ala Ala Pro Gly Ala Leu Gly Ser Leu
   1               5                  10                  15

 His Ala Gly Gly Ala Arg Leu Val Ala Ala Cys Ser Ala Trp Leu
                  20                  25                  30

 Cys Pro Gly Leu Arg Leu Pro Gly Ser Leu Ala Gly Arg Arg Ala
                  35                  40                  45

 Gly Pro Ala Ile Trp Ala Gln Gly Trp Val Pro Ala Ala Gly Gly
                  50                  55                  60

 Pro Ala Pro Lys Arg Gly Tyr Ser Ser Glu Met Lys Thr Glu Asp
                  65                  70                  75

 Glu Leu Arg Val Arg His Leu Glu Glu Glu Asn Arg Gly Ile Val
                  80                  85                  90

 Val Leu Gly Ile Asn Arg Ala Tyr Gly Lys Asn Ser Leu Ser Lys
                  95                 100                 105

 Asn Leu Ile Lys Met Leu Ser Lys Ala Val Asp Ala Leu Lys Ser
                 110                 115                 120

 Asp Lys Lys Val Arg Thr Ile Ile Ile Arg Ser Glu Val Pro Gly
                 125                 130                 135

 Ile Phe Cys Ala Gly Ala Asp Leu Lys Glu Arg Ala Lys Met Ser
                 140                 145                 150

 Ser Ser Glu Val Gly Pro Phe Val Ser Lys Ile Arg Ala Val Ile
                 155                 160                 165

 Asn Asp Ile Ala Asn Leu Pro Val Pro Thr Ile Ala Ala Ile Asp
                 170                 175                 180

 Gly Leu Ala Leu Gly Gly Gly Leu Glu Leu Ala Leu Ala Cys Asp
                 185                 190                 195

 Ile Arg Val Ala Ala Ser Ser Ala Lys Met Gly Leu Val Glu Thr
                 200                 205                 210

 Lys Leu Ala Ile Ile Pro Gly Gly Gly Gly Thr Gln Arg Leu Pro
                 215                 220                 225

 Arg Ala Ile Gly Met Ser Leu Ala Lys Glu Leu Ile Phe Ser Ala
                 230                 235                 240

 Arg Val Leu Asp Gly Lys Glu Ala Lys Ala Val Gly Leu Ile Ser
                 245                 250                 255

 His Val Leu Glu Gln Asn Gln Glu Gly Asp Ala Ala Tyr Arg Lys
                 260                 265                 270

 Ala Leu Asp Leu Ala Arg Glu Phe Leu Pro Gln Gly Pro Val Ala
                 275                 280                 285

 Met Arg Val Ala Lys Leu Ala Ile Asn Gln Gly Met Glu Val Asp
                 290                 295                 300

 Leu Val Thr Gly Leu Ala Ile Glu Glu Ala Cys Tyr Ala Gln Thr
                 305                 310                 315

 Ile Pro Thr Lys Asp Arg Leu Glu Gly Leu Leu Ala Phe Lys Glu
                 320                 325                 330

 Lys Arg Pro Pro Arg Tyr Lys Gly Glu
                 335

<210> 1283
<211> 3927
<212> DNA
<213> Homo sapien

<400> 1283
 gaattccggc ccccgtgtct gggcgtccgc ctcctggcct cctggctgag 50

 gggaagctga gtgggccacg gcccatgtgt cgcactcgcc tcggctccca 100

 cacagccgcc tctgctccag caaggatgtg gctcttccac actctgctct 150

 gcatagccag cctggccctg ctggccgctt tcaatgtgga tgtggcccgg 200

 ccctggctca cgcccaaggg aggtgcccct ttcgtgctca gctcccttct 250

 gcaccaagac cccagcacca accagacctg gctcctggtc accagcccca 300

 gaaccaagag gacaccaggg cccctccatc gatgttccct tgtccaggat 350

 gaaatccttt gccatcctgt agagcatgtc cccatcccca aggggaggca 400

 ccggggagtg accgttgtcc ggagccacca cggtgttttg atatgcattc 450

 aagtgctggt ccggcggcct cacagcctca gctcagaact cacaggcacc 500

 tgtagcctcc tgggccctga cctccgtccc caggctcagg ccaacttctt 550

 cgaccttgaa aatctcctgg atccagatgc acgtgtggac actggagact 600

 gctacagcaa caaagaaggc ggtggagaag acgatgtgaa cacagccagg 650

 cagcgccggg ctctggagaa ggaggaggag gaagacaagg aggaggagga 700

 agacgaggag gaggaggaag ctggcaccga gattgccatc atcctggatg 750

 gctcaggaag cattgatccc ccagactttc agagagccaa agacttcatc 800

 tccaacatga tgaggaactt ctatgaaaag tgttttgagt gcaactttgc 850

 cttggtgcag tatggaggag tgatccagac tgagtttgac cttcgggaca 900

 gccaggatgt gatggcctcc ctcgccagag tccagaacat cactcaagtg 950

 gggagtgtca ccaagactgc ctcagccatg caacacgtct tagacagcat 1000

 cttcacctca agccacggct ccaggagaaa ggcatccaag gtcatggtgg 1050

 tgctcaccga tggtggcata ttcgaggacc ccctcaacct tacgacagtc 1100

 atcaactccc ccaaaatgca gggtgttgag cgctttgcca ttggggtggg 1150

 agaagaattt aagagtgcta ggactgcgag ggaactgaac ctgatcgcct 1200

 cagacccgga tgagacccat gctttcaagg tgaccaacta catggcgctg 1250

 gatgggctgc tgagcaaact gcggtacaac atcatcagca tggaaggcac 1300

 ggttggagac gcccttcact accagctggc acagattggc ttcagtgctc 1350

 agatcctgga tgagcggcag gtgctgctcg gcgccgtcgg ggcctttgac 1400

 tggtccggag gggcgttgct ctacgacaca cgcagccgcc ggggccgctt 1450

 cctgaaccag acagcggcgg cggcggcaga cgcggaggct gcgcagtaca 1500

 gctacctggg ttacgctgtg gccgtgctgc acaagacctg cagcctctcc 1550

 tacgtcgcgg gggctccaca gtacaaacat catggggccg tgtttgagct 1600

 ccagaaggag ggcagagagg ccagcttcct gccagtgctg gagggagagc 1650

 agatggggtc ctattttggc tctgagctgt gccctgtgga cattgacatg 1700

 gatggaagca cggacttctt gctggtggct gctccatttt accacgttca 1750

 tggagaagaa ggcagagtct acgtgtaccg tctcagcgag caggatggtt 1800

 ctttctcctt ggcacgcata ctgagtgggc accccgggtt caccaatgcc 1850

 cgctttggct ttgccatggc ggctatgggg gatctcagtc aggataagct 1900

 cacagatgtg gccatcgggg cccccctgga aggttttggg gcagatgatg 1950

 gtgccagctt cggcagtgtg tatatctaca atggacactg ggacggcctc 2000

 tccgccagcc cctcgcagcg gatcagagcc tccacggtgg ccccaggact 2050

 ccagtacttc ggcatgtcca tggctggtgg ctttgatatt agtggcgacg 2100

 gccttgccga catcaccgtg ggcactctgg gccaggcggt tgtgttccgc 2150

 tcccggcctg tggttcgcct gaaggtctcc atggccttca cccccagcgc 2200

 actgcccatc ggcttcaacg gcgtcgtgaa tgtccgttta tgttttgaaa 2250

 tcagctctgt aaccacagcc tctgagtcag gcctccgtga ggcacttctc 2300

 aacttcacgc tggatgtgga tgtggggaag cagaggagac ggctgcagtg 2350

 ttcagacgta agaagctgtc tgggctgcct gagggagtgg agcagcggat 2400

 cccagctttg tgaggacctc ctgctcatgc ccacagaggg agagctctgt 2450

 gaggaggact gcttctccaa tgccagtgtc aaagtcagct accagctcca 2500

 gacccctgag ggacagacgg accatcccca gcccatcctg gaccgctaca 2550

 ctgagccctt tgccatcttc cagctgccct atgagaaggc ctgcaagaat 2600

 aagctgtttt gtgtcgcaga attacagttg gccaccaccg tctctcagca 2650

 ggagttggtg gtgggtctca caaaggagct gaccctgaac attaacctaa 2700

 ctaactccgg ggaagattcc tacatgacaa gcatggcctt gaattacccc 2750

 agaaacctgc agttgaagag gatgcaaaag cctccctctc caaacattca 2800

 gtgtgatgac cctcagccgg ttgcttctgt cctgatcatg aactgcagga 2850

 ttggtcaccc cgtcctcaag aggtcatctg ctcatgtttc agtcgtttgg 2900

 cagctagagg agaatgcctt tccaaacagg acagcagaca tcactgtgac 2950

 tgtcaccaat tccaatgaaa gacggtcttt ggccaacgag acccacaccc 3000

 ttcaattcag gcatggcttc gttgcagttc tgtccaaacc atccataatg 3050

 tacgtgaaca caggccaggg gctttctcac cacaaagaat tcctcttcca 3100

 tgtacatggg gagaacctct ttggagcaga ataccagttg caaatttgcg 3150

 tcccaaccaa attacgaggt ctccaggttg cagcagtgaa gaagctgacg 3200

 aggactcagg cctccacggt gtgcacctgg agtcaggagc gcgcttgtgc 3250

 gtacagttcg gttcagcatg tggaagaatg gcattcagtg agctgtgtca 3300

 tcgcttcaga taaagaaaat gtcaccgtgg ctgcagagat ctcctgggat 3350

 cactctgagg agttactaaa agatgtaact gaactgcaga tccttggtga 3400

 aatatctttc aacaaatctc tatatgaggg actgaatgca gagaaccaca 3450

 gaactaagat cactgtcgtc ttcctgaaag atgagaagta ccattctttg 3500

 cctatcatca ttaaaggcag cgttggtgga cttctggtgt tgatcgtgat 3550

 tctggtcatc ctgttcaagt gtggcttttt taaaagaaaa tatcaacaac 3600

 tgaacttgga gagcatcagg aaggcccagc tgaaatcaga gaatctgctc 3650

 gaagaagaga attaggacct gctatccact gggagaggct atcagccagt 3700

 cctgggactt ggagacccag catcctttgc attacttttt ccttcaggat 3750

 gatctagagc agcatggagc tgttggtaga atattagttt ttaaccatac 3800

 attgtcccaa aagtgtctgt gcattgtgca aaaagtaaac ttaggaaaca 3850

 tttggtatta aataaattta cacttttctt tgcaaaaaaa aaaaaaaaaa 3900

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 3927

<210> 1284
<211> 1179
<212> PRT
<213> Homo sapien

<400> 1284
 Met Trp Leu Phe His Thr Leu Leu Cys Ile Ala Ser Leu Ala Leu
   1               5                  10                  15

 Leu Ala Ala Phe Asn Val Asp Val Ala Arg Pro Trp Leu Thr Pro
                  20                  25                  30

 Lys Gly Gly Ala Pro Phe Val Leu Ser Ser Leu Leu His Gln Asp
                  35                  40                  45

 Pro Ser Thr Asn Gln Thr Trp Leu Leu Val Thr Ser Pro Arg Thr
                  50                  55                  60

 Lys Arg Thr Pro Gly Pro Leu His Arg Cys Ser Leu Val Gln Asp
                  65                  70                  75

 Glu Ile Leu Cys His Pro Val Glu His Val Pro Ile Pro Lys Gly
                  80                  85                  90

 Arg His Arg Gly Val Thr Val Val Arg Ser His His Gly Val Leu
                  95                 100                 105

 Ile Cys Ile Gln Val Leu Val Arg Arg Pro His Ser Leu Ser Ser
                 110                 115                 120

 Glu Leu Thr Gly Thr Cys Ser Leu Leu Gly Pro Asp Leu Arg Pro
                 125                 130                 135

 Gln Ala Gln Ala Asn Phe Phe Asp Leu Glu Asn Leu Leu Asp Pro
                 140                 145                 150

 Asp Ala Arg Val Asp Thr Gly Asp Cys Tyr Ser Asn Lys Glu Gly
                 155                 160                 165

 Gly Gly Glu Asp Asp Val Asn Thr Ala Arg Gln Arg Arg Ala Leu
                 170                 175                 180

 Glu Lys Glu Glu Glu Glu Asp Lys Glu Glu Glu Glu Asp Glu Glu
                 185                 190                 195

 Glu Glu Glu Ala Gly Thr Glu Ile Ala Ile Ile Leu Asp Gly Ser
                 200                 205                 210

 Gly Ser Ile Asp Pro Pro Asp Phe Gln Arg Ala Lys Asp Phe Ile
                 215                 220                 225

 Ser Asn Met Met Arg Asn Phe Tyr Glu Lys Cys Phe Glu Cys Asn
                 230                 235                 240

 Phe Ala Leu Val Gln Tyr Gly Gly Val Ile Gln Thr Glu Phe Asp
                 245                 250                 255

 Leu Arg Asp Ser Gln Asp Val Met Ala Ser Leu Ala Arg Val Gln
                 260                 265                 270

 Asn Ile Thr Gln Val Gly Ser Val Thr Lys Thr Ala Ser Ala Met
                 275                 280                 285

 Gln His Val Leu Asp Ser Ile Phe Thr Ser Ser His Gly Ser Arg
                 290                 295                 300

 Arg Lys Ala Ser Lys Val Met Val Val Leu Thr Asp Gly Gly Ile
                 305                 310                 315

 Phe Glu Asp Pro Leu Asn Leu Thr Thr Val Ile Asn Ser Pro Lys
                 320                 325                 330

 Met Gln Gly Val Glu Arg Phe Ala Ile Gly Val Gly Glu Glu Phe
                 335                 340                 345

 Lys Ser Ala Arg Thr Ala Arg Glu Leu Asn Leu Ile Ala Ser Asp
                 350                 355                 360

 Pro Asp Glu Thr His Ala Phe Lys Val Thr Asn Tyr Met Ala Leu
                 365                 370                 375

 Asp Gly Leu Leu Ser Lys Leu Arg Tyr Asn Ile Ile Ser Met Glu
                 380                 385                 390

 Gly Thr Val Gly Asp Ala Leu His Tyr Gln Leu Ala Gln Ile Gly
                 395                 400                 405

 Phe Ser Ala Gln Ile Leu Asp Glu Arg Gln Val Leu Leu Gly Ala
                 410                 415                 420

 Val Gly Ala Phe Asp Trp Ser Gly Gly Ala Leu Leu Tyr Asp Thr
                 425                 430                 435

 Arg Ser Arg Arg Gly Arg Phe Leu Asn Gln Thr Ala Ala Ala Ala
                 440                 445                 450

 Ala Asp Ala Glu Ala Ala Gln Tyr Ser Tyr Leu Gly Tyr Ala Val
                 455                 460                 465

 Ala Val Leu His Lys Thr Cys Ser Leu Ser Tyr Val Ala Gly Ala
                 470                 475                 480

 Pro Gln Tyr Lys His His Gly Ala Val Phe Glu Leu Gln Lys Glu
                 485                 490                 495

 Gly Arg Glu Ala Ser Phe Leu Pro Val Leu Glu Gly Glu Gln Met
                 500                 505                 510

 Gly Ser Tyr Phe Gly Ser Glu Leu Cys Pro Val Asp Ile Asp Met
                 515                 520                 525

 Asp Gly Ser Thr Asp Phe Leu Leu Val Ala Ala Pro Phe Tyr His
                 530                 535                 540

 Val His Gly Glu Glu Gly Arg Val Tyr Val Tyr Arg Leu Ser Glu
                 545                 550                 555

 Gln Asp Gly Ser Phe Ser Leu Ala Arg Ile Leu Ser Gly His Pro
                 560                 565                 570

 Gly Phe Thr Asn Ala Arg Phe Gly Phe Ala Met Ala Ala Met Gly
                 575                 580                 585

 Asp Leu Ser Gln Asp Lys Leu Thr Asp Val Ala Ile Gly Ala Pro
                 590                 595                 600

 Leu Glu Gly Phe Gly Ala Asp Asp Gly Ala Ser Phe Gly Ser Val
                 605                 610                 615

 Tyr Ile Tyr Asn Gly His Trp Asp Gly Leu Ser Ala Ser Pro Ser
                 620                 625                 630

 Gln Arg Ile Arg Ala Ser Thr Val Ala Pro Gly Leu Gln Tyr Phe
                 635                 640                 645

 Gly Met Ser Met Ala Gly Gly Phe Asp Ile Ser Gly Asp Gly Leu
                 650                 655                 660

 Ala Asp Ile Thr Val Gly Thr Leu Gly Gln Ala Val Val Phe Arg
                 665                 670                 675

 Ser Arg Pro Val Val Arg Leu Lys Val Ser Met Ala Phe Thr Pro
                 680                 685                 690

 Ser Ala Leu Pro Ile Gly Phe Asn Gly Val Val Asn Val Arg Leu
                 695                 700                 705

 Cys Phe Glu Ile Ser Ser Val Thr Thr Ala Ser Glu Ser Gly Leu
                 710                 715                 720

 Arg Glu Ala Leu Leu Asn Phe Thr Leu Asp Val Asp Val Gly Lys
                 725                 730                 735

 Gln Arg Arg Arg Leu Gln Cys Ser Asp Val Arg Ser Cys Leu Gly
                 740                 745                 750

 Cys Leu Arg Glu Trp Ser Ser Gly Ser Gln Leu Cys Glu Asp Leu
                 755                 760                 765

 Leu Leu Met Pro Thr Glu Gly Glu Leu Cys Glu Glu Asp Cys Phe
                 770                 775                 780

 Ser Asn Ala Ser Val Lys Val Ser Tyr Gln Leu Gln Thr Pro Glu
                 785                 790                 795

 Gly Gln Thr Asp His Pro Gln Pro Ile Leu Asp Arg Tyr Thr Glu
                 800                 805                 810

 Pro Phe Ala Ile Phe Gln Leu Pro Tyr Glu Lys Ala Cys Lys Asn
                 815                 820                 825

 Lys Leu Phe Cys Val Ala Glu Leu Gln Leu Ala Thr Thr Val Ser
                 830                 835                 840

 Gln Gln Glu Leu Val Val Gly Leu Thr Lys Glu Leu Thr Leu Asn
                 845                 850                 855

 Ile Asn Leu Thr Asn Ser Gly Glu Asp Ser Tyr Met Thr Ser Met
                 860                 865                 870

 Ala Leu Asn Tyr Pro Arg Asn Leu Gln Leu Lys Arg Met Gln Lys
                 875                 880                 885

 Pro Pro Ser Pro Asn Ile Gln Cys Asp Asp Pro Gln Pro Val Ala
                 890                 895                 900

 Ser Val Leu Ile Met Asn Cys Arg Ile Gly His Pro Val Leu Lys
                 905                 910                 915

 Arg Ser Ser Ala His Val Ser Val Val Trp Gln Leu Glu Glu Asn
                 920                 925                 930

 Ala Phe Pro Asn Arg Thr Ala Asp Ile Thr Val Thr Val Thr Asn
                 935                 940                 945

 Ser Asn Glu Arg Arg Ser Leu Ala Asn Glu Thr His Thr Leu Gln
                 950                 955                 960

 Phe Arg His Gly Phe Val Ala Val Leu Ser Lys Pro Ser Ile Met
                 965                 970                 975

 Tyr Val Asn Thr Gly Gln Gly Leu Ser His His Lys Glu Phe Leu
                 980                 985                 990

 Phe His Val His Gly Glu Asn Leu Phe Gly Ala Glu Tyr Gln Leu
                 995                1000                1005

 Gln Ile Cys Val Pro Thr Lys Leu Arg Gly Leu Gln Val Ala Ala
                1010                1015                1020

 Val Lys Lys Leu Thr Arg Thr Gln Ala Ser Thr Val Cys Thr Trp
                1025                1030                1035

 Ser Gln Glu Arg Ala Cys Ala Tyr Ser Ser Val Gln His Val Glu
                1040                1045                1050

 Glu Trp His Ser Val Ser Cys Val Ile Ala Ser Asp Lys Glu Asn
                1055                1060                1065

 Val Thr Val Ala Ala Glu Ile Ser Trp Asp His Ser Glu Glu Leu
                1070                1075                1080

 Leu Lys Asp Val Thr Glu Leu Gln Ile Leu Gly Glu Ile Ser Phe
                1085                1090                1095

 Asn Lys Ser Leu Tyr Glu Gly Leu Asn Ala Glu Asn His Arg Thr
                1100                1105                1110

 Lys Ile Thr Val Val Phe Leu Lys Asp Glu Lys Tyr His Ser Leu
                1115                1120                1125

 Pro Ile Ile Ile Lys Gly Ser Val Gly Gly Leu Leu Val Leu Ile
                1130                1135                1140

 Val Ile Leu Val Ile Leu Phe Lys Cys Gly Phe Phe Lys Arg Lys
                1145                1150                1155

 Tyr Gln Gln Leu Asn Leu Glu Ser Ile Arg Lys Ala Gln Leu Lys
                1160                1165                1170

 Ser Glu Asn Leu Leu Glu Glu Glu Asn
                1175

<210> 1285
<211> 3493
<212> DNA
<213> Homo sapien

<400> 1285
 agcggccggg gccacgatgg agcgcgacgg ctgcgcgggg ggcgggagcc 50

 gcggcggcga gggcgggcgc gctccccggg agggcccggc ggggaacggc 100

 cgcgatcggg gccgcagcca cgctgccgag gcgcccgggg acccgcaggc 150

 ggccgcgtcc ttgctggccc ctatggacgt gggggaggag ccgctggaga 200

 aggcggcgcg cgcccgcact gccaaggacc ccaacaccta taaagtactc 250

 tcgctggtat tgtcagtatg tgtgttaaca acaatacttg gttgtatatt 300

 tgggttgaaa ccaagctgtg ccaaagaagt taaaagttgc aaaggtcgct 350

 gtttcgagag aacatttggg aactgtcgct gtgatgctgc ctgtgttgag 400

 cttggaaact gctgtttaga ttaccaggag acgtgcatag aaccagaaca 450

 tatatggact tgcaacaaat tcaggtgtgg tgagaaaagg ttgaccagaa 500

 gcctctgtgc ctgttcagat gactgcaagg acaagggcga ctgctgcatc 550

 aactacagtt ctgtgtgtca aggtgagaaa agttgggtag aagaaccatg 600

 tgagagcatt aatgagccac agtgcccagc agggtttgaa acgcctccta 650

 ccctcttatt ttctttggat ggattcaggg cagaatattt acacacttgg 700

 ggtggacttc ttcctgttat tagcaaacta aaaaaatgtg gaacatatac 750

 taaaaacatg agaccggtat atccaacaaa aactttcccc aatcactaca 800

 gcattgtcac cggattgtat ccagaatctc atggcataat cgacaataaa 850

 atgtatgatc ccaaaatgaa tgcttccttt tcacttaaaa gtaaagagaa 900

 atttaatcct gagtggtaca aaggagaacc aatttgggtc acagctaagt 950

 atcaaggcct caagtctggc acatttttct ggccaggatc agatgtggaa 1000

 attaacggaa ttttcccaga catctataaa atgtataatg gttcagtacc 1050

 atttgaagaa aggattttag ctgttcttca gtggctacag cttcctaaag 1100

 atgaaagacc acacttttac actctgtatt tagaagaacc agattcttca 1150

 ggtcattcat atggaccagt cagcagtgaa gtcatcaaag ccttgcagag 1200

 ggttgatggt atggttggta tgctgatgga tggtctgaaa gagctgaact 1250

 tgcacagatg cctgaacctc atccttattt cagatcatgg catggaacaa 1300

 ggcagttgta agaaatacat atatctgaat aaatatttgg gggatgttaa 1350

 aaatattaaa gttatctatg gacctgcagc tcgattgaga ccctctgatg 1400

 tcccagataa atactattca tttaactatg aaggcattgc ccgaaatctt 1450

 tcttgccggg aaccaaacca gcacttcaaa ccttacctga aacatttctt 1500

 acctaagcgt ttgcactttg ctaagagtga tagaattgag cccttgacat 1550

 tctatttgga ccctcagtgg caacttgcat tgaatccctc agaaaggaaa 1600

 tattgtggaa gtggatttca tggctctgac aatgtatttt caaatatgca 1650

 agccctcttt gttggctatg gacctggatt caagcatggc attgaggctg 1700

 acacctttga aaacattgaa gtctataact taatgtgtga tttactgaat 1750

 ttgacaccgg ctcctaataa cggaactcat ggaagtctta accaccttct 1800

 aaagaatcct gtttatacgc caaagcatcc caaagaagtg caccccctgg 1850

 tacagtgccc cttcacaaga aaccccagag ataaccttgg ctgctcatgt 1900

 aacccttcga ttttgccgat tgaggatttt caaacacagt tcaatctgac 1950

 tgtggcagaa gagaagatta ttaagcatga aactttaccc tatggaagac 2000

 ctagagttct ccagaaggaa aacaccatct gtcttctttc ccagcaccag 2050

 tttatgagtg gatacagcca agacatctta atgccccttt ggacatccta 2100

 taccgtggac agaaatgaca gtttctctac ggaagacttc tccaactgtc 2150

 tgtaccagga ctttagaatt cctcttagtc ctgtccataa atgttcattt 2200

 tataaaaata acaccaaagt gagttacggg ttcctctccc caccacaact 2250

 aaataaaaat tcaagtggaa tatattctga agctttgctt actacaaata 2300

 tagtgccaat gtaccagagt tttcaagtta tatggcgcta ctttcatgac 2350

 accctactgc gaaagtatgc tgaagaaaga aatggtgtca atgtcgtcag 2400

 tggtcctgtg tttgactttg attatgatgg acgttgtgat tccttagaga 2450

 atctgaggca aaaaagaaga gtcatccgta accaagaaat tttgattcca 2500

 actcacttct ttattgtgct aacaagctgt aaagatacat ctcagacgcc 2550

 tttgcactgt gaaaacctag acaccttagc tttcattttg cctcacagga 2600

 ctgataacag cgagagctgt gtgcatggga agcatgactc ctcatgggtt 2650

 gaagaattgt taatgttaca cagagcacgg atcacagatg ttgagcacat 2700

 cactggactc agcttctatc aacaaagaaa agagccagtt tcagacattt 2750

 taaagttgaa aacacatttg ccaaccttta gccaagaaga ctgatatgtt 2800

 ttttatcccc aaacaccatg aatctttttg agagaacctt atattttata 2850

 tagtcctcta gctacactat tgcattgttc agaaactgtc gaccagagtt 2900

 agaacggagc cctcggtgat gcggacatct cagggaaact tgcgtactca 2950

 gcacagcagt ggagagtgtt cctgttgaat cttgcacata tttgaatgtg 3000

 taagcattgt atacattgat caagttcggg ggaataaaga cagaccacac 3050

 ctaaaactgc ctttctgctt ctcttaaagg agaagtagct gtgaacattg 3100

 tctggatacc agatatttga atctttctta ctattggtaa taaaccttga 3150

 tggcattggg caaacagtag acttatagta gggttggggt agcccatgtt 3200

 atgtgactat ctttatgaga attttaaagt ggttctggat atcttttaac 3250

 ttggagtttc atttcttttc attgtaatca aaaaaaaaat taacagaagc 3300

 caaaatactt ctgagacctt gtttcaatct ttgctgtata tcccctcaaa 3350

 atccaagtta ttaatcttat gtgttttctt tttaattttt tgattggatt 3400

 tctttagatt taatggttca aatgagttca actttgaggg acgatctttg 3450

 aatatactta cctattataa aatcttactt tgtatttgta ttt 3493

<210> 1286
<211> 873
<212> PRT
<213> Homo sapien

<400> 1286
 Met Asp Val Gly Glu Glu Pro Leu Glu Lys Ala Ala Arg Ala Arg
   1               5                  10                  15

 Thr Ala Lys Asp Pro Asn Thr Tyr Lys Val Leu Ser Leu Val Leu
                  20                  25                  30

 Ser Val Cys Val Leu Thr Thr Ile Leu Gly Cys Ile Phe Gly Leu
                  35                  40                  45

 Lys Pro Ser Cys Ala Lys Glu Val Lys Ser Cys Lys Gly Arg Cys
                  50                  55                  60

 Phe Glu Arg Thr Phe Gly Asn Cys Arg Cys Asp Ala Ala Cys Val
                  65                  70                  75

 Glu Leu Gly Asn Cys Cys Leu Asp Tyr Gln Glu Thr Cys Ile Glu
                  80                  85                  90

 Pro Glu His Ile Trp Thr Cys Asn Lys Phe Arg Cys Gly Glu Lys
                  95                 100                 105

 Arg Leu Thr Arg Ser Leu Cys Ala Cys Ser Asp Asp Cys Lys Asp
                 110                 115                 120

 Lys Gly Asp Cys Cys Ile Asn Tyr Ser Ser Val Cys Gln Gly Glu
                 125                 130                 135

 Lys Ser Trp Val Glu Glu Pro Cys Glu Ser Ile Asn Glu Pro Gln
                 140                 145                 150

 Cys Pro Ala Gly Phe Glu Thr Pro Pro Thr Leu Leu Phe Ser Leu
                 155                 160                 165

 Asp Gly Phe Arg Ala Glu Tyr Leu His Thr Trp Gly Gly Leu Leu
                 170                 175                 180

 Pro Val Ile Ser Lys Leu Lys Lys Cys Gly Thr Tyr Thr Lys Asn
                 185                 190                 195

 Met Arg Pro Val Tyr Pro Thr Lys Thr Phe Pro Asn His Tyr Ser
                 200                 205                 210

 Ile Val Thr Gly Leu Tyr Pro Glu Ser His Gly Ile Ile Asp Asn
                 215                 220                 225

 Lys Met Tyr Asp Pro Lys Met Asn Ala Ser Phe Ser Leu Lys Ser
                 230                 235                 240

 Lys Glu Lys Phe Asn Pro Glu Trp Tyr Lys Gly Glu Pro Ile Trp
                 245                 250                 255

 Val Thr Ala Lys Tyr Gln Gly Leu Lys Ser Gly Thr Phe Phe Trp
                 260                 265                 270

 Pro Gly Ser Asp Val Glu Ile Asn Gly Ile Phe Pro Asp Ile Tyr
                 275                 280                 285

 Lys Met Tyr Asn Gly Ser Val Pro Phe Glu Glu Arg Ile Leu Ala
                 290                 295                 300

 Val Leu Gln Trp Leu Gln Leu Pro Lys Asp Glu Arg Pro His Phe
                 305                 310                 315

 Tyr Thr Leu Tyr Leu Glu Glu Pro Asp Ser Ser Gly His Ser Tyr
                 320                 325                 330

 Gly Pro Val Ser Ser Glu Val Ile Lys Ala Leu Gln Arg Val Asp
                 335                 340                 345

 Gly Met Val Gly Met Leu Met Asp Gly Leu Lys Glu Leu Asn Leu
                 350                 355                 360

 His Arg Cys Leu Asn Leu Ile Leu Ile Ser Asp His Gly Met Glu
                 365                 370                 375

 Gln Gly Ser Cys Lys Lys Tyr Ile Tyr Leu Asn Lys Tyr Leu Gly
                 380                 385                 390

 Asp Val Lys Asn Ile Lys Val Ile Tyr Gly Pro Ala Ala Arg Leu
                 395                 400                 405

 Arg Pro Ser Asp Val Pro Asp Lys Tyr Tyr Ser Phe Asn Tyr Glu
                 410                 415                 420

 Gly Ile Ala Arg Asn Leu Ser Cys Arg Glu Pro Asn Gln His Phe
                 425                 430                 435

 Lys Pro Tyr Leu Lys His Phe Leu Pro Lys Arg Leu His Phe Ala
                 440                 445                 450

 Lys Ser Asp Arg Ile Glu Pro Leu Thr Phe Tyr Leu Asp Pro Gln
                 455                 460                 465

 Trp Gln Leu Ala Leu Asn Pro Ser Glu Arg Lys Tyr Cys Gly Ser
                 470                 475                 480

 Gly Phe His Gly Ser Asp Asn Val Phe Ser Asn Met Gln Ala Leu
                 485                 490                 495

 Phe Val Gly Tyr Gly Pro Gly Phe Lys His Gly Ile Glu Ala Asp
                 500                 505                 510

 Thr Phe Glu Asn Ile Glu Val Tyr Asn Leu Met Cys Asp Leu Leu
                 515                 520                 525

 Asn Leu Thr Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn
                 530                 535                 540

 His Leu Leu Lys Asn Pro Val Tyr Thr Pro Lys His Pro Lys Glu
                 545                 550                 555

 Val His Pro Leu Val Gln Cys Pro Phe Thr Arg Asn Pro Arg Asp
                 560                 565                 570

 Asn Leu Gly Cys Ser Cys Asn Pro Ser Ile Leu Pro Ile Glu Asp
                 575                 580                 585

 Phe Gln Thr Gln Phe Asn Leu Thr Val Ala Glu Glu Lys Ile Ile
                 590                 595                 600

 Lys His Glu Thr Leu Pro Tyr Gly Arg Pro Arg Val Leu Gln Lys
                 605                 610                 615

 Glu Asn Thr Ile Cys Leu Leu Ser Gln His Gln Phe Met Ser Gly
                 620                 625                 630

 Tyr Ser Gln Asp Ile Leu Met Pro Leu Trp Thr Ser Tyr Thr Val
                 635                 640                 645

 Asp Arg Asn Asp Ser Phe Ser Thr Glu Asp Phe Ser Asn Cys Leu
                 650                 655                 660

 Tyr Gln Asp Phe Arg Ile Pro Leu Ser Pro Val His Lys Cys Ser
                 665                 670                 675

 Phe Tyr Lys Asn Asn Thr Lys Val Ser Tyr Gly Phe Leu Ser Pro
                 680                 685                 690

 Pro Gln Leu Asn Lys Asn Ser Ser Gly Ile Tyr Ser Glu Ala Leu
                 695                 700                 705

 Leu Thr Thr Asn Ile Val Pro Met Tyr Gln Ser Phe Gln Val Ile
                 710                 715                 720

 Trp Arg Tyr Phe His Asp Thr Leu Leu Arg Lys Tyr Ala Glu Glu
                 725                 730                 735

 Arg Asn Gly Val Asn Val Val Ser Gly Pro Val Phe Asp Phe Asp
                 740                 745                 750

 Tyr Asp Gly Arg Cys Asp Ser Leu Glu Asn Leu Arg Gln Lys Arg
                 755                 760                 765

 Arg Val Ile Arg Asn Gln Glu Ile Leu Ile Pro Thr His Phe Phe
                 770                 775                 780

 Ile Val Leu Thr Ser Cys Lys Asp Thr Ser Gln Thr Pro Leu His
                 785                 790                 795

 Cys Glu Asn Leu Asp Thr Leu Ala Phe Ile Leu Pro His Arg Thr
                 800                 805                 810

 Asp Asn Ser Glu Ser Cys Val His Gly Lys His Asp Ser Ser Trp
                 815                 820                 825

 Val Glu Glu Leu Leu Met Leu His Arg Ala Arg Ile Thr Asp Val
                 830                 835                 840

 Glu His Ile Thr Gly Leu Ser Phe Tyr Gln Gln Arg Lys Glu Pro
                 845                 850                 855

 Val Ser Asp Ile Leu Lys Leu Lys Thr His Leu Pro Thr Phe Ser
                 860                 865                 870

 Gln Glu Asp


<210> 1287
<211> 438
<212> DNA
<213> Homo sapien

<400> 1287
 ggcacgaggg cccgtgccgc cccagccgct gccgcctgca ccggacccgg 50

 agccgccatg cccaagtgtc ccaagtgcaa caaggaggtg tacttcgccg 100

 agagggtgac ctctctgggc aaggactggc atcggccctg cctgaagtgc 150

 gagaaatgtg ggaagacgct gacctctggg ggccacgctg agcacgaagg 200

 caaaccctac tgcaaccacc cctgctacgc agccatgttt gggcctaaag 250

 gctttgggcg gggcggagcc gagagccaca ctttcaagta aaccaggtgg 300

 tggagacccc atccttggct gcttgcaggg ccactgtcca ggcaaatgcc 350

 aggccttgtc cccagatgcc cagggctccc ttgttgcccc taatgctctc 400

 agtaaacctg aacacttgga aaaaaaaaaa aaaaaaaa 438

<210> 1288
<211> 77
<212> PRT
<213> Homo sapien

<400> 1288
 Met Pro Lys Cys Pro Lys Cys Asn Lys Glu Val Tyr Phe Ala Glu
   1               5                  10                  15

 Arg Val Thr Ser Leu Gly Lys Asp Trp His Arg Pro Cys Leu Lys
                  20                  25                  30

 Cys Glu Lys Cys Gly Lys Thr Leu Thr Ser Gly Gly His Ala Glu
                  35                  40                  45

 His Glu Gly Lys Pro Tyr Cys Asn His Pro Cys Tyr Ala Ala Met
                  50                  55                  60

 Phe Gly Pro Lys Gly Phe Gly Arg Gly Gly Ala Glu Ser His Thr
                  65                  70                  75

 Phe Lys


<210> 1289
<211> 4599
<212> DNA
<213> Homo sapien

<400> 1289
 ccctgtgtct aggtcgtttg ggaaacgcct tggagagtca agaataaatt 50

 tgcaggtcaa acaatggatg actggaaaag tcggcttgta atcaagagca 100

 tgcttcccca tttcgccatg gtgggaaatc gtcaggagcc cagaaagctc 150

 caggaatcgg gaaagaagcc ctcgtggatg gaggaagaag atttatcttt 200

 tctctacaag agcagcccag gaagaaagca tcaggggaac tgttaacagg 250

 agacaagaag aagaccactt ccagtttcca gacatggctg atgggggcta 300

 ccctaataaa attaagaggc cttgccttga agatgtcacc cttgcaatgg 350

 gcccaggtgc tcatcctagt actgcttgtg cagaactgca ggtccctcca 400

 ttgacaataa atcctagccc tgcggctatg ggagtggctg gccagtcatt 450

 actgctggag aataacccta tgaatggcaa catcatgggc tcaccatttg 500

 tagtaccaca gactacagaa gtgggactga aagggcccac tgttccttac 550

 tatgagaaaa tcaacagcgt gccggctgta gaccaggagc ttcaagagct 600

 gctagaggag ctcaccaaaa ttcaagaccc ttctccaaat gagctagatc 650

 ttgagaagat actggggacg aagccagaag agccactggt tttagatcat 700

 ccccaggcaa ccctaagcac aactcccaag ccttcggttc agatgtcaca 750

 cttggagagc ctggcttcca gcaaggagtt tgcttctagt tgcagccaag 800

 ttactggcat gtcacttcag atcccatcct cctccacagg gatcagctat 850

 tcgattcctt ccaccagtaa gcagatagtg tcaccgagtt cttcaatggc 900

 acagtccaag agccaggtcc aggccatgct ccctgtcgct ctgcccccct 950

 taccagtgcc tcagtggcat cacgcccacc agctgaaggc gttggcagcc 1000

 agcaagcagg ggtctgctac aaagcagcaa gggcccaccc ccagttggtc 1050

 tggtctgcct cctccaggac tctctccacc ttcccgccca gtgccatcac 1100

 tacagccacc accgctgcca ctgccaccac caccaccccc attcagcccc 1150

 cagagcctca tggtgtcctg catgtcgtcc aataccttgt cgggtagcac 1200

 tctccgaggc tctcccaatg ccttactgtc aagcatgacg tccagcagca 1250

 atgctgccct ggggcccgcc atgccctatg ctcctgagaa gctccccagc 1300

 cctgctctca ctcaacagcc gcagttcggc cctcagagct ccattcttgc 1350

 caacctcatg tcctctacca tcaaaacccc tcaaggacac ctgatgtctg 1400

 ctctgcctgc cagcaaccct gggccgtccc caccctatcg cccagagaag 1450

 ctctctagcc caggcttgcc acagcagtcc ttcaccccac agtgttccct 1500

 gatccgaagc ctcactccca ccagtaatct tctaagccag caacagcagc 1550

 agcagcagca gcagcagcaa gcaaatgtga tctttaagcc cataagcagc 1600

 aactcatcca aaaccctgag catgatcatg cagcagggga tggcaagctc 1650

 cagcccagga gccacggagc catttacttt tggcaacacc aagcccttgt 1700

 cccattttgt ttctgagccg ggtccccaga agatgccctc catgcctacc 1750

 acctctaggc agccttccct gctccactac ctgcagcagc cgacaccaac 1800

 gcaggcctcc tcagccactg cctcctccac ggccactgcc accttgcagc 1850

 tgcagcagca gcagcagcaa cagcagcagc agcctgacca ttcttcattc 1900

 cttctgcagc agatgatgca gcaaccccag cgttttcagc gatcagtggc 1950

 ctcagattcc atgcctgctc tgcccagaca ggtctgttgc catctgtttg 2000

 catggacttc tgcagctagc tcggtgaagc cccagcatca acacgggaac 2050

 tctttcacta gcaggcaaga tcctcagcct ggagacgtgt caccgtctaa 2100

 cattactcat gtagacaaag cctgcaagct tggggaagcc aggcaccccc 2150

 aggtcagcct cgggcgacag cccccgtcct gccaggccct ggggagtgag 2200

 tccttcctgc ccggcagctc ctttgctcat gagctggccc gagtcacctc 2250

 ctcgtacagc acctcagagg cagcgccctg gggcagctgg gatccgaagg 2300

 cctggaggca ggtgcccgct ccactactgc ctagctgcga cgccacagca 2350

 agaggaacag agatcaggtc ttatggcaat gacccctgaa cggcagaatg 2400

 catatatctc ccaacagatg agtccatttg aagccgtcca agaacaagtc 2450

 acctccaagt gtagccggat caaggcaagc cccccatcta gcaagcactt 2500

 gatgccaccc agaactgggc ttcttcagaa caatctgagt ccaggaatga 2550

 tcccactcac caggcaccag agctgcgagg gcatgggagt gatctcacca 2600

 actctgggga agcggcaagg aattttcacc tccagccccc agtgtcccat 2650

 cctctcacac tcaggccaga ctcccctggg cagacttgac tctgtctgcc 2700

 agcatatgca gagccccaag gccaccccac cagaagtgcc cctgcctggg 2750

 ttctgtccca gctccctggg cacccagtcc ttgagtcccc accagctcag 2800

 acggcctagt gtgccaagaa tgcccactgc gttcaacaat gctgcatggg 2850

 tcacagcggc agcagctgtg accacagcag tttcggggaa aacacccctc 2900

 agccaagtgg ataatagcgt tcagcagcac tcaccttctg gccaggcctg 2950

 ccttcagagg ccatctgatt gggaggcaca agtgcccgct gcgatgggaa 3000

 cacaagtgcc cctggccaac aaccccagct tcagcctgct gggcagccag 3050

 agcctcaggc agagcccggt acagggcccg gtgcctgtag caaacaccac 3100

 caagttcctc cagcagggta tggccagctt tagtcccctg agccccatac 3150

 agggcatcga gccaccaagc tatgtggctg ctgctgccac cgctgctgct 3200

 gcttctgccg ttgctgccag ccagttccca ggtccgttcg acagaacgga 3250

 tattccccct gagctgccac ctgccgactt tttgcgccag ccccaacccc 3300

 cactaaatga tctgatttcg tcacctgact gcaatgaggt agatttcatt 3350

 gaagctctct tgaaaggctc ctgtgtgagc ccagatgaag actgggtgtg 3400

 caacttgagg ctgatcgacg acattttgga acagcatgct gctgctcaaa 3450

 atgccacagc ccagaattct gggcaagtca cccaggatgc tggggcactt 3500

 taaatctgag caggatgccc atagaaaccc ccatggtgac atcactctag 3550

 gaagtggtgt cgatccatac ccgcagttgt ctcccgttac aatttgagtg 3600

 gtgttgtcag cccatgctta tccctctctc tacctgtgac aaaatggaaa 3650

 gctggtgatt tttcaagcta cgtgtacata tttgaaaatt ttgtaaatgg 3700

 ttttcctaaa cattaatgac agaagtattt atacttcatt ttgtgacttt 3750

 gtaaataaag cgacggcttt tgtttcagta gagttgtgtt tactatgcat 3800

 tgttttgtgt ttattataca atgttacaaa tatgcagacc gtgttgtttg 3850

 ctccagtgat accttgttaa gctaggtggc tgagtcgctt atggttttaa 3900

 tgcaatgagc aatgtggata tgaccaagag ttgttgtgca agttgacaaa 3950

 tgccaaatag aaaaccactt ggccatttat ttctatgttc actaaaaatc 4000

 ctattgcctt gtgtgattct taatctcttt tgcgaacctt tcagtctccg 4050

 ctagctcttt cctaatgagc tttacagcag aagctgtttt atcgttaagt 4100

 gccccacaga gacactttac caggaggctg ggagagttct ccagatttgg 4150

 gagaggcgca gagacagtgt gtgagccgag ccctgtctca gcaatccacc 4200

 tggaggagct agagtatcct cctcccttta ccattcagac cgagagaaaa 4250

 agcccagctt gtgtgcaccc tcgtggggtt aaggcgagct gttcctggtt 4300

 taaagccttt cagtatttgt tttgatgtaa ggctctgtgg tttggggggg 4350

 aacatctgta aacattatta gttgatttgg ggtttgtctt tgatggtttc 4400

 tatctgcaat tatcgtcatg tatatttaag tgtctgttat agaaaaccca 4450

 cacccactgt cctgtaaact tttctcagtg tccagacttt ctgtaatcac 4500

 attttaattg ccacctcgta tttcacctct acatttgaaa tctggcgtct 4550

 gtttcaagcc agtgtgtttt ttcttcgttc tgtaataaac agccaggag 4599

<210> 1290
<211> 701
<212> PRT
<213> Homo sapien

<400> 1290
 Met Ala Asp Gly Gly Tyr Pro Asn Lys Ile Lys Arg Pro Cys Leu
   1               5                  10                  15

 Glu Asp Val Thr Leu Ala Met Gly Pro Gly Ala His Pro Ser Thr
                  20                  25                  30

 Ala Cys Ala Glu Leu Gln Val Pro Pro Leu Thr Ile Asn Pro Ser
                  35                  40                  45

 Pro Ala Ala Met Gly Val Ala Gly Gln Ser Leu Leu Leu Glu Asn
                  50                  55                  60

 Asn Pro Met Asn Gly Asn Ile Met Gly Ser Pro Phe Val Val Pro
                  65                  70                  75

 Gln Thr Thr Glu Val Gly Leu Lys Gly Pro Thr Val Pro Tyr Tyr
                  80                  85                  90

 Glu Lys Ile Asn Ser Val Pro Ala Val Asp Gln Glu Leu Gln Glu
                  95                 100                 105

 Leu Leu Glu Glu Leu Thr Lys Ile Gln Asp Pro Ser Pro Asn Glu
                 110                 115                 120

 Leu Asp Leu Glu Lys Ile Leu Gly Thr Lys Pro Glu Glu Pro Leu
                 125                 130                 135

 Val Leu Asp His Pro Gln Ala Thr Leu Ser Thr Thr Pro Lys Pro
                 140                 145                 150

 Ser Val Gln Met Ser His Leu Glu Ser Leu Ala Ser Ser Lys Glu
                 155                 160                 165

 Phe Ala Ser Ser Cys Ser Gln Val Thr Gly Met Ser Leu Gln Ile
                 170                 175                 180

 Pro Ser Ser Ser Thr Gly Ile Ser Tyr Ser Ile Pro Ser Thr Ser
                 185                 190                 195

 Lys Gln Ile Val Ser Pro Ser Ser Ser Met Ala Gln Ser Lys Ser
                 200                 205                 210

 Gln Val Gln Ala Met Leu Pro Val Ala Leu Pro Pro Leu Pro Val
                 215                 220                 225

 Pro Gln Trp His His Ala His Gln Leu Lys Ala Leu Ala Ala Ser
                 230                 235                 240

 Lys Gln Gly Ser Ala Thr Lys Gln Gln Gly Pro Thr Pro Ser Trp
                 245                 250                 255

 Ser Gly Leu Pro Pro Pro Gly Leu Ser Pro Pro Ser Arg Pro Val
                 260                 265                 270

 Pro Ser Leu Gln Pro Pro Pro Leu Pro Leu Pro Pro Pro Pro Pro
                 275                 280                 285

 Pro Phe Ser Pro Gln Ser Leu Met Val Ser Cys Met Ser Ser Asn
                 290                 295                 300

 Thr Leu Ser Gly Ser Thr Leu Arg Gly Ser Pro Asn Ala Leu Leu
                 305                 310                 315

 Ser Ser Met Thr Ser Ser Ser Asn Ala Ala Leu Gly Pro Ala Met
                 320                 325                 330

 Pro Tyr Ala Pro Glu Lys Leu Pro Ser Pro Ala Leu Thr Gln Gln
                 335                 340                 345

 Pro Gln Phe Gly Pro Gln Ser Ser Ile Leu Ala Asn Leu Met Ser
                 350                 355                 360

 Ser Thr Ile Lys Thr Pro Gln Gly His Leu Met Ser Ala Leu Pro
                 365                 370                 375

 Ala Ser Asn Pro Gly Pro Ser Pro Pro Tyr Arg Pro Glu Lys Leu
                 380                 385                 390

 Ser Ser Pro Gly Leu Pro Gln Gln Ser Phe Thr Pro Gln Cys Ser
                 395                 400                 405

 Leu Ile Arg Ser Leu Thr Pro Thr Ser Asn Leu Leu Ser Gln Gln
                 410                 415                 420

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Ala Asn Val Ile Phe Lys
                 425                 430                 435

 Pro Ile Ser Ser Asn Ser Ser Lys Thr Leu Ser Met Ile Met Gln
                 440                 445                 450

 Gln Gly Met Ala Ser Ser Ser Pro Gly Ala Thr Glu Pro Phe Thr
                 455                 460                 465

 Phe Gly Asn Thr Lys Pro Leu Ser His Phe Val Ser Glu Pro Gly
                 470                 475                 480

 Pro Gln Lys Met Pro Ser Met Pro Thr Thr Ser Arg Gln Pro Ser
                 485                 490                 495

 Leu Leu His Tyr Leu Gln Gln Pro Thr Pro Thr Gln Ala Ser Ser
                 500                 505                 510

 Ala Thr Ala Ser Ser Thr Ala Thr Ala Thr Leu Gln Leu Gln Gln
                 515                 520                 525

 Gln Gln Gln Gln Gln Gln Gln Gln Pro Asp His Ser Ser Phe Leu
                 530                 535                 540

 Leu Gln Gln Met Met Gln Gln Pro Gln Arg Phe Gln Arg Ser Val
                 545                 550                 555

 Ala Ser Asp Ser Met Pro Ala Leu Pro Arg Gln Val Cys Cys His
                 560                 565                 570

 Leu Phe Ala Trp Thr Ser Ala Ala Ser Ser Val Lys Pro Gln His
                 575                 580                 585

 Gln His Gly Asn Ser Phe Thr Ser Arg Gln Asp Pro Gln Pro Gly
                 590                 595                 600

 Asp Val Ser Pro Ser Asn Ile Thr His Val Asp Lys Ala Cys Lys
                 605                 610                 615

 Leu Gly Glu Ala Arg His Pro Gln Val Ser Leu Gly Arg Gln Pro
                 620                 625                 630

 Pro Ser Cys Gln Ala Leu Gly Ser Glu Ser Phe Leu Pro Gly Ser
                 635                 640                 645

 Ser Phe Ala His Glu Leu Ala Arg Val Thr Ser Ser Tyr Ser Thr
                 650                 655                 660

 Ser Glu Ala Ala Pro Trp Gly Ser Trp Asp Pro Lys Ala Trp Arg
                 665                 670                 675

 Gln Val Pro Ala Pro Leu Leu Pro Ser Cys Asp Ala Thr Ala Arg
                 680                 685                 690

 Gly Thr Glu Ile Arg Ser Tyr Gly Asn Asp Pro
                 695                 700

<210> 1291
<211> 2772
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2262
<223> Unknown base

<400> 1291
 gtcattttga aagactgtga aactggagcc aattctccat catcacacag 50

 gaagctgagt acttcctact tggtcaggat cttgaaactt gaattcataa 100

 aaacccagaa agccccagaa acaaagactt cacggacaaa gtcccttgga 150

 accagagaga agccgggatg gaaactccaa acaccacaga ggactatgac 200

 acgaccacag agtttgacta tggggatgca actccgtgcc agaaggtgaa 250

 cgagagggcc tttggggccc aactgctgcc ccctctgtac tccttggtat 300

 ttgtcattgg cctggttgga aacatcctgg tggtcctggt ccttgtgcaa 350

 tacaagaggc taaaaaacat gaccagcatc tacctcctga acctggccat 400

 ttctgacctg ctcttcctgt tcacgcttcc cttctggatc gactacaagt 450

 tgaaggatga ctgggttttt ggtgatgcca tgtgtaagat cctctctggg 500

 ttttattaca caggcttgta cagcgagatc tttttcatca tcctgctgac 550

 gattgacagg tacctggcca tcgtccacgc cgtgtttgcc ttgcgggcac 600

 ggaccgtcac ttttggtgtc atcaccagca tcatcatttg ggccctggcc 650

 atcttggctt ccatgccagg cttatacttt tccaagaccc aatgggaatt 700

 cactcaccac acctgcagcc ttcactttcc tcacgaaagc ctacgagagt 750

 ggaagctgtt tcaggctctg aaactgaacc tctttgggct ggtattgcct 800

 ttgttggtca tgatcatctg ctacacaggg attataaaga ttctgctaag 850

 acgaccaaat gagaagaaat ccaaagctgt ccgtttgatt tttgtcatca 900

 tgatcatctt ttttctcttt tggaccccct acaatttgac tatacttatt 950

 tctgttttcc aagacttcct gttcacccat gagtgtgagc agagcagaca 1000

 tttggacctg gctgtgcaag tgacggaggt gatcgcctac acgcactgct 1050

 gtgtcaaccc agtgatctac gccttcgttg gtgagaggtt ccggaagtac 1100

 ctgcggcagt tgttccacag gcgtgtggct gtgcacctgg ttaaatggct 1150

 ccccttcctc tccgtggaca ggctggagag ggtcagctcc acatctccct 1200

 ccacagggga gcatgaactc tctgctgggt tctgactcag accataggag 1250

 gccaacccaa aataagcagg cgtgacctgc caggcacact gagccagcag 1300

 cctggctctc ccagccaggt tctgactctt ggcacagcat ggagtcacag 1350

 ccacttggga tagagaggga atgtaatggt ggcctggggc ttctgaggct 1400

 tctggggctt cagtcttttc catgaacttc tcccctggta gaaagaagat 1450

 gaatgagcaa aaccaaatat tccagagact gggactaagt gtaccagaga 1500

 agggcttgga ctcaagcaag atttcagatt tgtgaccatt agcatttgtc 1550

 aacaaagtca cccacttccc actattgctt gcacaaacca attaaaccca 1600

 gtagtggtga ctgtgggctc cattcaaagt gagctcctaa gccatgggag 1650

 acactgatgt atgaggaatt tctgttcttc catcacctcc ccccccccgc 1700

 caccctccca ctgccaaaga acttggaaat agtgatttcc acagtgactc 1750

 cactctgagt cccagagcca atcagtagcc agcatctgcc tccccttcac 1800

 tcccaccgca ggatttgggc tcttggaatc ctggggaaca tagaactcat 1850

 gacggaagag ttgagaccta acgagaaata gaaatgggga actactgctg 1900

 gcagtggaac taagaaagcc cttaggaaga atttttatat ccactaaaat 1950

 caaacaattc agggagtggg ctaagcacgg gccatatgaa taacatggtg 2000

 tgcttcttaa aatagccata aaggggaggg actcatcatt tccatttacc 2050

 cttcttttct gactattttt cagaatctct cttcttttca agttgggtga 2100

 tatgttggta gattctaatg gctttattgc agcgattaat aacaggcaaa 2150

 aggaagcagg gttggtttcc cttctttttg ttcttcatct aagccttctg 2200

 gttttatggg tcagagttcc gactgccatc ttggacttgt cagcaaaaaa 2250

 aaaaaataat antaataata aggcctgctg tgtaagctga cagtatttgt 2300

 agctgatagg gggttgggag gaaagtgtct actaggaggg tggggtgaga 2350

 ttctgtgttg atgtaggagg ccgagaaggc ccttaactca aagtagctta 2400

 tttatccaaa atgttctgga tgcatcatct ccaaccaagg accccttatt 2450

 tatcatgcct ttgttctctt ttccctcaga tgtatatttc tttaaaaata 2500

 attttcctaa taacaaaact tatttctaaa acagcttaaa aattcaaaga 2550

 aaaaccccaa acactgacat tacctacact tccactaccc aaagacaaaa 2600

 tgtgcccact gtgtgctttt gagtgtattt tcttttagtt tgttttttgt 2650

 tgggtgcata tttatgataa taacaatgat ggacttcaat tgtactcact 2700

 gttctattgt tggttttaat tagcagcaag ttgtgatcac tttcccaggt 2750

 gaataaatca tttcaaagca tt 2772

<210> 1292
<211> 355
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2262
<223> Unknown amino acid

<400> 1292
 Met Glu Thr Pro Asn Thr Thr Glu Asp Tyr Asp Thr Thr Thr Glu
   1               5                  10                  15

 Phe Asp Tyr Gly Asp Ala Thr Pro Cys Gln Lys Val Asn Glu Arg
                  20                  25                  30

 Ala Phe Gly Ala Gln Leu Leu Pro Pro Leu Tyr Ser Leu Val Phe
                  35                  40                  45

 Val Ile Gly Leu Val Gly Asn Ile Leu Val Val Leu Val Leu Val
                  50                  55                  60

 Gln Tyr Lys Arg Leu Lys Asn Met Thr Ser Ile Tyr Leu Leu Asn
                  65                  70                  75

 Leu Ala Ile Ser Asp Leu Leu Phe Leu Phe Thr Leu Pro Phe Trp
                  80                  85                  90

 Ile Asp Tyr Lys Leu Lys Asp Asp Trp Val Phe Gly Asp Ala Met
                  95                 100                 105

 Cys Lys Ile Leu Ser Gly Phe Tyr Tyr Thr Gly Leu Tyr Ser Glu
                 110                 115                 120

 Ile Phe Phe Ile Ile Leu Leu Thr Ile Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val His Ala Val Phe Ala Leu Arg Ala Arg Thr Val Thr Phe Gly
                 140                 145                 150

 Val Ile Thr Ser Ile Ile Ile Trp Ala Leu Ala Ile Leu Ala Ser
                 155                 160                 165

 Met Pro Gly Leu Tyr Phe Ser Lys Thr Gln Trp Glu Phe Thr His
                 170                 175                 180

 His Thr Cys Ser Leu His Phe Pro His Glu Ser Leu Arg Glu Trp
                 185                 190                 195

 Lys Leu Phe Gln Ala Leu Lys Leu Asn Leu Phe Gly Leu Val Leu
                 200                 205                 210

 Pro Leu Leu Val Met Ile Ile Cys Tyr Thr Gly Ile Ile Lys Ile
                 215                 220                 225

 Leu Leu Arg Arg Pro Asn Glu Lys Lys Ser Lys Ala Val Arg Leu
                 230                 235                 240

 Ile Phe Val Ile Met Ile Ile Phe Phe Leu Phe Trp Thr Pro Tyr
                 245                 250                 255

 Asn Leu Thr Ile Leu Ile Ser Val Phe Gln Asp Phe Leu Phe Thr
                 260                 265                 270

 His Glu Cys Glu Gln Ser Arg His Leu Asp Leu Ala Val Gln Val
                 275                 280                 285

 Thr Glu Val Ile Ala Tyr Thr His Cys Cys Val Asn Pro Val Ile
                 290                 295                 300

 Tyr Ala Phe Val Gly Glu Arg Phe Arg Lys Tyr Leu Arg Gln Leu
                 305                 310                 315

 Phe His Arg Arg Val Ala Val His Leu Val Lys Trp Leu Pro Phe
                 320                 325                 330

 Leu Ser Val Asp Arg Leu Glu Arg Val Ser Ser Thr Ser Pro Ser
                 335                 340                 345

 Thr Gly Glu His Glu Leu Ser Ala Gly Phe
                 350                 355

<210> 1293
<211> 2156
<212> DNA
<213> Homo sapien

<400> 1293
 ggcacgagcc cagaaacaaa gacttcacgg acaaagtccc ttggaaccag 50

 agagaagccg ggatggaaac tccaaacacc acagaggact atgacacgac 100

 cacagagttt gactatgggg atgcaactcc gtgccagaag gtgaacgaga 150

 gggcctttgg ggcccaactg ctgccccctc tgtactcctt ggtatttgtc 200

 attggcctgg ttggaaacat cctggtggtc ctggtccttg tgcaatacaa 250

 gaggctaaaa aacatgacca gcatctacct cctgaacctg gccatttctg 300

 acctgctctt cctgttcacg cttcccttct ggatcgacta caagttgaag 350

 gatgactggg tttttggtga tgccatgtgt aagatcctct ctgggtttta 400

 ttacacaggc ttgtacagcg agatcttttt catcatcctg ctgacgattg 450

 acaggtacct ggccatcgtc cacgccgtgt ttgccttgcg ggcacggacc 500

 gtcacttttg gtgtcatcac cagcatcatc atttgggccc tggccatctt 550

 ggcttccatg ccaggcttat acttttccaa gacccaatgg gaattcactc 600

 accacacctg cagccttcac tttcctcacg aaagcctacg agagtggaag 650

 ctgtttcagg ctctgaaact gaacctcttt gggctggtat tgcctttgtt 700

 ggtcatgatc atctgctaca cagggattat aaagattctg ctaagacgac 750

 caaatgagaa gaaatccaaa gctgtccgtt tgatttttgt catcatgatc 800

 atcttttttc tcttttggac cccctacaat ttgactatac ttatttctgt 850

 tttccaagac ttcctgttca cccatgagtg tgagcagagc agacatttgg 900

 acctggctgt gcaagtgacg gaggtgatcg cctacacgca ctgctgtgtc 950

 aacccagtga tctacgcctt cgttggtgag aggttccgga agtacctgcg 1000

 gcagttgttc cacaggcgtg tggctgtgca cctggttaaa tggctcccct 1050

 tcctctccgt ggacaggctg gagagggtca gctccacatc tccctccaca 1100

 ggggagcatg aactctctgc tgggttctga ctcagaccat aggaggccaa 1150

 cccaaaataa gcaggcgtga cctgccaggc acactgagcc agcagcctgg 1200

 ctctcccagc caggttctga ctcttggcac agcatggagt cacagccact 1250

 tgggatagag agggaatgta atggtggcct ggggcttctg aggcttctgg 1300

 ggcttcagtc ttttccatga acttctcccc tggtagaaag aagatgaatg 1350

 agcaaaacca aatattccag agactgggac taagtgtacc agagaagggc 1400

 ttggactcaa gcaagatttc agatttgtga ccattagcat ttgtcaacaa 1450

 agtcacccac ttcccactat tgcttgcaca aaccaattaa acccagtagt 1500

 ggtgactgtg ggctccattc aaagtgagct cctaagccat gggagacact 1550

 gatgtatgag gaatttctgt tcttccatca cctccccccc cccgccaccc 1600

 tcccactgcc aagaacttgg aaatagtgat ttccacagtg actccactct 1650

 gagtcccaga gccaatcagt agccagcatc tgcctcccct tcactcccac 1700

 cgcaggattt gggctcttgg aatcctgggg aacatagaac tcatgacgga 1750

 agagttgaga cctaacgaga aatagaaatg ggggaactac tgctggcagt 1800

 ggaactaaga aagcccttag gaagaatttt tatatccact aaaatcaaac 1850

 aattcaggga gtgggctaag cacgggccat atgaataaca tggtgtgctt 1900

 cttaaaatag ccataaaggg gagggactca tcatttccat ttacccttct 1950

 tttctgacta tttttcagaa tctctcttct tttcaagttg ggtgatatgt 2000

 tggtagattc taatggcttt attgcagcga ttaataacag gcaaaaggaa 2050

 gcagggttgg tttcccttct ttttgttctt catctaagcc ttctggtttt 2100

 atgggtcaga gttccgactg ccatcttgga cttgtcagca aaaaaaaaaa 2150

 aaaaaa 2156

<210> 1294
<211> 355
<212> PRT
<213> Homo sapien

<400> 1294
 Met Glu Thr Pro Asn Thr Thr Glu Asp Tyr Asp Thr Thr Thr Glu
   1               5                  10                  15

 Phe Asp Tyr Gly Asp Ala Thr Pro Cys Gln Lys Val Asn Glu Arg
                  20                  25                  30

 Ala Phe Gly Ala Gln Leu Leu Pro Pro Leu Tyr Ser Leu Val Phe
                  35                  40                  45

 Val Ile Gly Leu Val Gly Asn Ile Leu Val Val Leu Val Leu Val
                  50                  55                  60

 Gln Tyr Lys Arg Leu Lys Asn Met Thr Ser Ile Tyr Leu Leu Asn
                  65                  70                  75

 Leu Ala Ile Ser Asp Leu Leu Phe Leu Phe Thr Leu Pro Phe Trp
                  80                  85                  90

 Ile Asp Tyr Lys Leu Lys Asp Asp Trp Val Phe Gly Asp Ala Met
                  95                 100                 105

 Cys Lys Ile Leu Ser Gly Phe Tyr Tyr Thr Gly Leu Tyr Ser Glu
                 110                 115                 120

 Ile Phe Phe Ile Ile Leu Leu Thr Ile Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val His Ala Val Phe Ala Leu Arg Ala Arg Thr Val Thr Phe Gly
                 140                 145                 150

 Val Ile Thr Ser Ile Ile Ile Trp Ala Leu Ala Ile Leu Ala Ser
                 155                 160                 165

 Met Pro Gly Leu Tyr Phe Ser Lys Thr Gln Trp Glu Phe Thr His
                 170                 175                 180

 His Thr Cys Ser Leu His Phe Pro His Glu Ser Leu Arg Glu Trp
                 185                 190                 195

 Lys Leu Phe Gln Ala Leu Lys Leu Asn Leu Phe Gly Leu Val Leu
                 200                 205                 210

 Pro Leu Leu Val Met Ile Ile Cys Tyr Thr Gly Ile Ile Lys Ile
                 215                 220                 225

 Leu Leu Arg Arg Pro Asn Glu Lys Lys Ser Lys Ala Val Arg Leu
                 230                 235                 240

 Ile Phe Val Ile Met Ile Ile Phe Phe Leu Phe Trp Thr Pro Tyr
                 245                 250                 255

 Asn Leu Thr Ile Leu Ile Ser Val Phe Gln Asp Phe Leu Phe Thr
                 260                 265                 270

 His Glu Cys Glu Gln Ser Arg His Leu Asp Leu Ala Val Gln Val
                 275                 280                 285

 Thr Glu Val Ile Ala Tyr Thr His Cys Cys Val Asn Pro Val Ile
                 290                 295                 300

 Tyr Ala Phe Val Gly Glu Arg Phe Arg Lys Tyr Leu Arg Gln Leu
                 305                 310                 315

 Phe His Arg Arg Val Ala Val His Leu Val Lys Trp Leu Pro Phe
                 320                 325                 330

 Leu Ser Val Asp Arg Leu Glu Arg Val Ser Ser Thr Ser Pro Ser
                 335                 340                 345

 Thr Gly Glu His Glu Leu Ser Ala Gly Phe
                 350                 355

<210> 1295
<211> 776
<212> DNA
<213> Homo sapien

<400> 1295
 aaggacacgg gcagcagaca gtggtcagtc ctttcttggc tctgctgaca 50

 ctcgagccca cattccgtca cctgctcaga atcatgcagg tctccactgc 100

 tgcccttgct gtcctcctct gcaccatggc tctctgcaac cagttctctg 150

 catcacttgc tgctgacacg ccgaccgcct gctgcttcag ctacacctcc 200

 cggcagattc cacagaattt catagctgac tactttgaga cgagcagcca 250

 gtgctccaag cccggtgtca tcttcctaac caagcgaagc cggcaggtct 300

 gtgctgaccc cagtgaggag tgggtccaga aatatgtcag cgacctagag 350

 ctgagtgcct gaggggtcca gaagcttcga ggcccagcga cctcggtggg 400

 ccagtgggga ggagcaggag cctgagcctt gggaaacatg cgtgtgacct 450

 ccacagctac ctcttctatg gactggttgt tgccaaacag ccacactgtg 500

 ggactcttct taacttaaat tttaatttat ttatactatt tagtttttgt 550

 aatttatttt cgatttcaca gtgtgtttgt gattgtttgc tctgagagtt 600

 cccctgtccc ctcccccttc cctcacaccg cgtctggtga caaccgagtg 650

 gctgtcatca gcctgtgtag gcagtcatgg caccaaagcc accagactga 700

 caaatgtgta tcggatgctt ttgttcaggg ctgtgatcgg cctggggaaa 750

 taataaagca cgctctttta aaaggt 776

<210> 1296
<211> 92
<212> PRT
<213> Homo sapien

<400> 1296
 Met Gln Val Ser Thr Ala Ala Leu Ala Val Leu Leu Cys Thr Met
   1               5                  10                  15

 Ala Leu Cys Asn Gln Phe Ser Ala Ser Leu Ala Ala Asp Thr Pro
                  20                  25                  30

 Thr Ala Cys Cys Phe Ser Tyr Thr Ser Arg Gln Ile Pro Gln Asn
                  35                  40                  45

 Phe Ile Ala Asp Tyr Phe Glu Thr Ser Ser Gln Cys Ser Lys Pro
                  50                  55                  60

 Gly Val Ile Phe Leu Thr Lys Arg Ser Arg Gln Val Cys Ala Asp
                  65                  70                  75

 Pro Ser Glu Glu Trp Val Gln Lys Tyr Val Ser Asp Leu Glu Leu
                  80                  85                  90

 Ser Ala


<210> 1297
<211> 884
<212> DNA
<213> Homo sapien

<400> 1297
 gctcttacag catggccgcc ggtactgcag ctgccttagc gtttttgagt 50

 caggagagcc gaacgcgggc cgggggtgtc gggggcctac gggtcccggc 100

 cccggtcact atggacagtt ttttcttcgg ctgtgagctc tccggccaca 150

 cccgctcctt cacctttaag gtagaggaag aggatgatgc ggagcacgtg 200

 ctggcactaa ccatgctctg cctcaccgag ggagccaaag acgagtgtaa 250

 tgtggtagaa gttgtggccc ggaaccatga ccatcaggag atcgcagtcc 300

 ctgtggccaa cctcaagctg tcctgccaac ccatgctcag tctggatgac 350

 ttccagctcc aaccacctgt aaccttccgc ctgaagtcgg gctctggccc 400

 tgtgcggatc actgggcggc accagattgt tacgatgagc aatgatgttt 450

 ctgaggagga gagcgaggaa gaggaagagg acagtgatga ggaagaagtt 500

 gagctgtgcc ccatccttcc tgccaaaaag caggggggca ggccctagcc 550

 ctcctaggtc agctccatgt gccatgcacc gccatgcacc ctgttccctg 600

 acaaagtttc aacaattgta aatatttctt ccttgaagag gagagcttgg 650

 gtgggggttg ggtgggaggg acttgggtct ttggtgctag gagagggcct 700

 gtgctccaca cagccgtggt tttctgattt tcaccatgcc cggggcctcc 750

 cttcccacct gcctgtgaga attggaggtt agtgcctgaa gctcagagct 800

 acacattttt aatagtttaa acatttttgg ataaaggttg aaataaagtg 850

 gtgtggagtt tttgcaaaaa aaaaaaaaaa aaaa 884

<210> 1298
<211> 178
<212> PRT
<213> Homo sapien

<400> 1298
 Met Ala Ala Gly Thr Ala Ala Ala Leu Ala Phe Leu Ser Gln Glu
   1               5                  10                  15

 Ser Arg Thr Arg Ala Gly Gly Val Gly Gly Leu Arg Val Pro Ala
                  20                  25                  30

 Pro Val Thr Met Asp Ser Phe Phe Phe Gly Cys Glu Leu Ser Gly
                  35                  40                  45

 His Thr Arg Ser Phe Thr Phe Lys Val Glu Glu Glu Asp Asp Ala
                  50                  55                  60

 Glu His Val Leu Ala Leu Thr Met Leu Cys Leu Thr Glu Gly Ala
                  65                  70                  75

 Lys Asp Glu Cys Asn Val Val Glu Val Val Ala Arg Asn His Asp
                  80                  85                  90

 His Gln Glu Ile Ala Val Pro Val Ala Asn Leu Lys Leu Ser Cys
                  95                 100                 105

 Gln Pro Met Leu Ser Leu Asp Asp Phe Gln Leu Gln Pro Pro Val
                 110                 115                 120

 Thr Phe Arg Leu Lys Ser Gly Ser Gly Pro Val Arg Ile Thr Gly
                 125                 130                 135

 Arg His Gln Ile Val Thr Met Ser Asn Asp Val Ser Glu Glu Glu
                 140                 145                 150

 Ser Glu Glu Glu Glu Glu Asp Ser Asp Glu Glu Glu Val Glu Leu
                 155                 160                 165

 Cys Pro Ile Leu Pro Ala Lys Lys Gln Gly Gly Arg Pro
                 170                 175

<210> 1299
<211> 538
<212> DNA
<213> Homo sapien

<400> 1299
 gctacactag agcagagtac gagtctgagg cggagggagt aatggcagga 50

 caagcgttta gaaagtttct tccactcttt gaccgagtat tggttgaaag 100

 gagtgctgct gaaactgtaa ccaaaggagg cattatgctt ccagaaaaat 150

 ctcaaggaaa agtattgcaa gcaacagtag tcgctgttgg atcgggttct 200

 aaaggaaagg gtggagagat tcaaccagtt agcgtgaaag ttggagataa 250

 agttcttctc ccagaatatg gaggcaccaa agtagttcta gatgacaagg 300

 attatttcct atttagagat ggtgacattc ttggaaagta cgtagactga 350

 aataagtcac tattgaaatg gcatcaacat gatgctgccc attccactga 400

 agttctgaaa tctttcgtca tgtaaataat ttccatattt ctcttttata 450

 ataaactaat gataactaat gacatccagt gtctccaaaa ttgtttcctt 500

 gtactgatat aaacacttcc aaataaaaat atgtaaat 538

<210> 1300
<211> 102
<212> PRT
<213> Homo sapien

<400> 1300
 Met Ala Gly Gln Ala Phe Arg Lys Phe Leu Pro Leu Phe Asp Arg
   1               5                  10                  15

 Val Leu Val Glu Arg Ser Ala Ala Glu Thr Val Thr Lys Gly Gly
                  20                  25                  30

 Ile Met Leu Pro Glu Lys Ser Gln Gly Lys Val Leu Gln Ala Thr
                  35                  40                  45

 Val Val Ala Val Gly Ser Gly Ser Lys Gly Lys Gly Gly Glu Ile
                  50                  55                  60

 Gln Pro Val Ser Val Lys Val Gly Asp Lys Val Leu Leu Pro Glu
                  65                  70                  75

 Tyr Gly Gly Thr Lys Val Val Leu Asp Asp Lys Asp Tyr Phe Leu
                  80                  85                  90

 Phe Arg Asp Gly Asp Ile Leu Gly Lys Tyr Val Asp
                  95                 100

<210> 1301
<211> 1421
<212> DNA
<213> Homo sapien

<400> 1301
 gaagcaggcc tgagcctccc caaaggcagc tcctggggac tcccaggacc 50

 acaggctgag acgagacgca gggtggctgg aggaagtgag aggtgaactc 100

 agcctgggac tggctgggcg agactctcca cctgctccct gggaccatcg 150

 cccaccatgg ctgtggccca gcagctgcgg gccgagagtg actttgaaca 200

 gcttccggat gatgttgcca tctcggccaa cattgctgac atcgaggaga 250

 agagaggctt caccagccac tttgttttcg tcatcgaggt gaagacaaaa 300

 ggaggatcca agtacctcat ctaccgccgc taccgccagt tccatgcttt 350

 gcagagcaag ctggaggagc gcttcgggcc agacagcaag agcagtgccc 400

 tggcctgtac cctgcccaca ctcccagcca aagtctacgt gggtgtgaaa 450

 caggagatcg ccgagatgcg gatacctgcc ctcaacgcct acatgaagag 500

 cctgctcagc ctgccggtct gggtgctgat ggatgaggac gtccggatct 550

 tcttttacca gtcgccctat gactcagagc aggtgcccca ggcactccgc 600

 cggctccgcc cgcgcacccg gaaagtcaag agcgtgtccc cacagggcaa 650

 cagcgttgac cgcatggcag ctccgagagc agaggctcta tttgacttca 700

 ctggaaacag caaactggag ctgaatttca aagctggaga tgtgatcttc 750

 ctcctcagtc ggatcaacaa agactggctg gagggcactg tccggggagc 800

 cacgggcatc ttccctctct ccttcgtgaa gatcctcaaa gacttccctg 850

 aggaggacga ccccaccaac tggctgcgtt gctactacta cgaagacacc 900

 atcagcacca tcaagtctgt ggcctgggag ggaggggcct gtccagcctt 950

 cctgccatcc ctacgaccac cgcccctcac atcaccttct catgggtccc 1000

 tctcccactc caaagccccc agtggctccc agatgagcca caatgctgta 1050

 acaagccatc aacgtccagg gtggcctggc cagcctcatt cccctttccc 1100

 ccaccccaca ccccacttcc agcctgatgc ctccttactc cagcctgtca 1150

 cccccttagg gacatcgcgg tggaggaaga tctcagcagc actcccctat 1200

 tgaaagacct gctggagctc acaaggcggg agttccagag agaggacata 1250

 gctctgaatt accgggacgc tgagggggat ctggttcggc tgctgtcgga 1300

 tgaggacgta gcgctcatgg tgcggcaggc tcgtggcctc ccctcccaga 1350

 agcgcctctt cccctggaag ctgcacatca cgcagaagga caactacagg 1400

 gtctacaaca cgatgccatg a 1421

<210> 1302
<211> 348
<212> PRT
<213> Homo sapien

<400> 1302
 Met Ala Val Ala Gln Gln Leu Arg Ala Glu Ser Asp Phe Glu Gln
   1               5                  10                  15

 Leu Pro Asp Asp Val Ala Ile Ser Ala Asn Ile Ala Asp Ile Glu
                  20                  25                  30

 Glu Lys Arg Gly Phe Thr Ser His Phe Val Phe Val Ile Glu Val
                  35                  40                  45

 Lys Thr Lys Gly Gly Ser Lys Tyr Leu Ile Tyr Arg Arg Tyr Arg
                  50                  55                  60

 Gln Phe His Ala Leu Gln Ser Lys Leu Glu Glu Arg Phe Gly Pro
                  65                  70                  75

 Asp Ser Lys Ser Ser Ala Leu Ala Cys Thr Leu Pro Thr Leu Pro
                  80                  85                  90

 Ala Lys Val Tyr Val Gly Val Lys Gln Glu Ile Ala Glu Met Arg
                  95                 100                 105

 Ile Pro Ala Leu Asn Ala Tyr Met Lys Ser Leu Leu Ser Leu Pro
                 110                 115                 120

 Val Trp Val Leu Met Asp Glu Asp Val Arg Ile Phe Phe Tyr Gln
                 125                 130                 135

 Ser Pro Tyr Asp Ser Glu Gln Val Pro Gln Ala Leu Arg Arg Leu
                 140                 145                 150

 Arg Pro Arg Thr Arg Lys Val Lys Ser Val Ser Pro Gln Gly Asn
                 155                 160                 165

 Ser Val Asp Arg Met Ala Ala Pro Arg Ala Glu Ala Leu Phe Asp
                 170                 175                 180

 Phe Thr Gly Asn Ser Lys Leu Glu Leu Asn Phe Lys Ala Gly Asp
                 185                 190                 195

 Val Ile Phe Leu Leu Ser Arg Ile Asn Lys Asp Trp Leu Glu Gly
                 200                 205                 210

 Thr Val Arg Gly Ala Thr Gly Ile Phe Pro Leu Ser Phe Val Lys
                 215                 220                 225

 Ile Leu Lys Asp Phe Pro Glu Glu Asp Asp Pro Thr Asn Trp Leu
                 230                 235                 240

 Arg Cys Tyr Tyr Tyr Glu Asp Thr Ile Ser Thr Ile Lys Ser Val
                 245                 250                 255

 Ala Trp Glu Gly Gly Ala Cys Pro Ala Phe Leu Pro Ser Leu Arg
                 260                 265                 270

 Pro Pro Pro Leu Thr Ser Pro Ser His Gly Ser Leu Ser His Ser
                 275                 280                 285

 Lys Ala Pro Ser Gly Ser Gln Met Ser His Asn Ala Val Thr Ser
                 290                 295                 300

 His Gln Arg Pro Gly Trp Pro Gly Gln Pro His Ser Pro Phe Pro
                 305                 310                 315

 His Pro Thr Pro His Phe Gln Pro Asp Ala Ser Leu Leu Gln Pro
                 320                 325                 330

 Val Thr Pro Leu Gly Thr Ser Arg Trp Arg Lys Ile Ser Ala Ala
                 335                 340                 345

 Leu Pro Tyr


<210> 1303
<211> 3963
<212> DNA
<213> Homo sapien

<400> 1303
 cctgcgtgtc cctctgcgct ccgactggtg cgacttctcc ctgcgctagc 50

 gaggcagggt tttggcctcg cctctcgcga gatcgcctcc tgttgctgcc 100

 gccgccgctc ctggccactg actggcggcg cctgcgcagc cgccatgttc 150

 ggttgctatg ctgcggccta ggagaggggg tgtgcttgag ggaggaggaa 200

 gagatagagg aggaggaggg ggaggaagag gaggtggaga aggagggggg 250

 tgactgagct cctcttgcac tctcacacac aaacgctgcc caggattacc 300

 cgccagctca cgccgcgcag tgcgcttttc cgctcctcgc gccccaccac 350

 caacattgtt ctctcaggac tcctgggtcc caggggtcgg aattgggcct 400

 gagcgggaga ggaaagagac ttggctttgg ccgcggggtc ggaggattgg 450

 ggccaggccc cctcccccac gcacttttgg gggtgtggat tatctcatcc 500

 ctgcagggag gtaggagagg tcgccggctg cccgcctccc tgccacctcc 550

 ccagcggcgc cggcccgcgg ctgcccagca gcatgaggtg gtgctggcgg 600

 ctccgggtcg tggcgcgacc gctgcggcgg cggctgctcg gggggcgctg 650

 aggtagcccc ccggagcggc acggaggacg cgcttctcct ctgcgcgccg 700

 gggcctcgag gctttttttc tccagccgag aggacgcggc tgtgatatac 750

 gaagactttg tgtggacagt aatgacctca cgtttccgat tgcctgctgg 800

 cagaacctac aatgtacgag catcagagtt ggcccgagac agacagcata 850

 ctgaagtggt ttgcaacatc cttcttctgg ataacactgt acaagctttc 900

 aaagtcaata aacatgatca ggggcaagtc ttgttggatg tcgtcttcaa 950

 gcatctagat ttgactgagc aggactattt tggtttacag ttggctgatg 1000

 attccacaga taacccaagg tggctggatc caaacaaacc aataaggaag 1050

 cagctaaaga gaggatctcc ttacagtttg aactttagag tcaaattttt 1100

 tgtaagtgac cccaacaagt tacaagaaga atatacaagg taccagtatt 1150

 ttttgcaaat taaacaagac attcttactg gaagattacc ctgtccttct 1200

 aatactgctg cccttttagc ttcatttgct gttcagtctg aacttggaga 1250

 ctacgatcag tcagagaact tgtcaggcta cctctcagat tattctttca 1300

 ttcctaatca acctcaagat tttgaaaaag aaattgcaaa attacatcag 1350

 caacacatag gcttatctcc tgcagaagca gaatttaatt acctaaacac 1400

 agcacgtacc ttagaactct atggagttga attccactat gcaagggatc 1450

 agagtaacaa tgaaattatg attggagtga tgtcaggagg aattctgatt 1500

 tataagaaca gggtacgaat gaataccttt ccatggttga agattgtaaa 1550

 aatttctttt aagtgcaaac agttttttat tcaacttaga aaagaattgc 1600

 atgaatctag agaaacatta ttgggattta atatggtgaa ttacagagca 1650

 tgtaaaaatt tgtggaaagc atgtgtagaa catcacacat tcttccgttt 1700

 ggacagacca cttccacctc aaaagaattt ttttgcacat tattttacat 1750

 taggttcaaa attccggtac tgtgggagaa ctgaagtcca atcagttcag 1800

 tatggcaaag aaaaggcaaa taaagacagg gtatttgcaa gatccccaag 1850

 taagcccttg gcacggaaat taatggattg ggaagtagta agcagaaatt 1900

 caatatctga tgacaggtta gaaacacaaa gtcttccatc acgatctcca 1950

 ccgggaactc ctaatcatcg aaattctaca ttcacgcagg aaggaacccg 2000

 gttacgacca tcttcagttg gtcatttggt agaccatatg gttcatactt 2050

 ccccaagcga agtgtttgta aatcagagat ctccgtcatc aacacaagct 2100

 aatagcattg ttctggaatc atcaccatca caagagaccc ctggagatgg 2150

 gaagcctcca gctttaccac ccaaacagtc aaagaaaaac agttggaacc 2200

 aaattcatta ttcacattcg caacaagatc tagaaagtca tattaatgaa 2250

 acatttgata ttccatcttc tcctgaaaaa cccactccta atggtggtat 2300

 tccacatgat aatcttgtcc taatcagaat gaaacctgat gaaaatggga 2350

 ggtttggatt caatgtaaag ggaggatatg atcagaagat gcctgtgatt 2400

 gtgtctcgag tagcaccagg aacacctgct gacctctgtg tccctagact 2450

 gaatgaaggg gaccaagttg tactgatcaa tggtcgggac attgcagaac 2500

 acactcatga tcaggttgtg ctgtttatta aagctagttg tgagagacat 2550

 tctggggaac tcatgcttct agttcgacct aatgctgtat atgatgtagt 2600

 ggaagaaaag ctagaaaatg agccagattt ccagtatatt cctgagaaag 2650

 ccccactaga tagtgtgcat caggatgacc attccctgcg ggagtcaatg 2700

 atccagctag ctgaggggct tatcactgga acagtcctga cacagtttga 2750

 tcaactgtat cggaaaaaac ctggaatgac aatgtcctgt gccaaattac 2800

 ctcagaatat ttccaaaaat agatacagag atatttcgcc ttatgatgcc 2850

 acacgggtca ttttaaaagg taatgaagac tacatcaatg cgaactatat 2900

 aaatatggaa attccttctt ccagcattat aaatcagtac attgcttgtc 2950

 aagggccatt accacacact tgtacagatt tttggcagat gacttgggaa 3000

 caaggctcct ctatggttgt aatgttgacc acacaagttg aacgtggcag 3050

 agttaaatgt caccaatatt ggccagaacc cacaggcagt tcatcttatg 3100

 gatgctacca agttacctgc cactctgaag aaggaaacac tgcctatatc 3150

 ttcaggaaga tgaccctatt taaccaagag aaaaatgaaa gtcgtccact 3200

 cactcagatc cagtacatag cctggcctga ccatggagtc cctgatgatt 3250

 cgagtgactt tctagatttt gtttgtcatg tacgaaacaa gagggctggc 3300

 aaggaagaac ccgttgttgt ccattgcagt gctggaatcg gaagaactgg 3350

 ggttcttatt actatggaaa cagccatgtg tctcattgaa tgcaatcagc 3400

 cagtttatcc actagatatt gtaagaacaa tgagagatca gcgagccatg 3450

 atgatccaaa cacctagtca atacagattt gtatgtgaag ctattttgaa 3500

 agtttatgaa gaaggctttg ttaaaccctt aacaacatca acaaataaat 3550

 aagaaagcaa aaagatctgg gatatgtgtt ggaaaactgc tttcccttat 3600

 gttcactgtg ccataatgct gctcgcagga aatggcattt tacaaaaaaa 3650

 aaatgaagaa ctcaaaaaaa ctttgaaaac ttcagcactg ttgcacttta 3700

 tgttttaaaa aatgtcactc tttcaaaatc tataactcat gtatttgaag 3750

 actgtttcat gctttgctcc gaacaaatag taaataactg agtatgttca 3800

 gggtaattta tgaaattttg tggtggtgcc atgcaatccc cttttggtag 3850

 aattgccaca aacaaggctc aaaattctca tcatctctgt tatacacctg 3900

 tatcatgaaa gcaaaaagaa gtaaacatca ggagtcagct ctgaaaaaaa 3950

 aaaaaaaaaa aaa 3963

<210> 1304
<211> 926
<212> PRT
<213> Homo sapien

<400> 1304
 Met Thr Ser Arg Phe Arg Leu Pro Ala Gly Arg Thr Tyr Asn Val
   1               5                  10                  15

 Arg Ala Ser Glu Leu Ala Arg Asp Arg Gln His Thr Glu Val Val
                  20                  25                  30

 Cys Asn Ile Leu Leu Leu Asp Asn Thr Val Gln Ala Phe Lys Val
                  35                  40                  45

 Asn Lys His Asp Gln Gly Gln Val Leu Leu Asp Val Val Phe Lys
                  50                  55                  60

 His Leu Asp Leu Thr Glu Gln Asp Tyr Phe Gly Leu Gln Leu Ala
                  65                  70                  75

 Asp Asp Ser Thr Asp Asn Pro Arg Trp Leu Asp Pro Asn Lys Pro
                  80                  85                  90

 Ile Arg Lys Gln Leu Lys Arg Gly Ser Pro Tyr Ser Leu Asn Phe
                  95                 100                 105

 Arg Val Lys Phe Phe Val Ser Asp Pro Asn Lys Leu Gln Glu Glu
                 110                 115                 120

 Tyr Thr Arg Tyr Gln Tyr Phe Leu Gln Ile Lys Gln Asp Ile Leu
                 125                 130                 135

 Thr Gly Arg Leu Pro Cys Pro Ser Asn Thr Ala Ala Leu Leu Ala
                 140                 145                 150

 Ser Phe Ala Val Gln Ser Glu Leu Gly Asp Tyr Asp Gln Ser Glu
                 155                 160                 165

 Asn Leu Ser Gly Tyr Leu Ser Asp Tyr Ser Phe Ile Pro Asn Gln
                 170                 175                 180

 Pro Gln Asp Phe Glu Lys Glu Ile Ala Lys Leu His Gln Gln His
                 185                 190                 195

 Ile Gly Leu Ser Pro Ala Glu Ala Glu Phe Asn Tyr Leu Asn Thr
                 200                 205                 210

 Ala Arg Thr Leu Glu Leu Tyr Gly Val Glu Phe His Tyr Ala Arg
                 215                 220                 225

 Asp Gln Ser Asn Asn Glu Ile Met Ile Gly Val Met Ser Gly Gly
                 230                 235                 240

 Ile Leu Ile Tyr Lys Asn Arg Val Arg Met Asn Thr Phe Pro Trp
                 245                 250                 255

 Leu Lys Ile Val Lys Ile Ser Phe Lys Cys Lys Gln Phe Phe Ile
                 260                 265                 270

 Gln Leu Arg Lys Glu Leu His Glu Ser Arg Glu Thr Leu Leu Gly
                 275                 280                 285

 Phe Asn Met Val Asn Tyr Arg Ala Cys Lys Asn Leu Trp Lys Ala
                 290                 295                 300

 Cys Val Glu His His Thr Phe Phe Arg Leu Asp Arg Pro Leu Pro
                 305                 310                 315

 Pro Gln Lys Asn Phe Phe Ala His Tyr Phe Thr Leu Gly Ser Lys
                 320                 325                 330

 Phe Arg Tyr Cys Gly Arg Thr Glu Val Gln Ser Val Gln Tyr Gly
                 335                 340                 345

 Lys Glu Lys Ala Asn Lys Asp Arg Val Phe Ala Arg Ser Pro Ser
                 350                 355                 360

 Lys Pro Leu Ala Arg Lys Leu Met Asp Trp Glu Val Val Ser Arg
                 365                 370                 375

 Asn Ser Ile Ser Asp Asp Arg Leu Glu Thr Gln Ser Leu Pro Ser
                 380                 385                 390

 Arg Ser Pro Pro Gly Thr Pro Asn His Arg Asn Ser Thr Phe Thr
                 395                 400                 405

 Gln Glu Gly Thr Arg Leu Arg Pro Ser Ser Val Gly His Leu Val
                 410                 415                 420

 Asp His Met Val His Thr Ser Pro Ser Glu Val Phe Val Asn Gln
                 425                 430                 435

 Arg Ser Pro Ser Ser Thr Gln Ala Asn Ser Ile Val Leu Glu Ser
                 440                 445                 450

 Ser Pro Ser Gln Glu Thr Pro Gly Asp Gly Lys Pro Pro Ala Leu
                 455                 460                 465

 Pro Pro Lys Gln Ser Lys Lys Asn Ser Trp Asn Gln Ile His Tyr
                 470                 475                 480

 Ser His Ser Gln Gln Asp Leu Glu Ser His Ile Asn Glu Thr Phe
                 485                 490                 495

 Asp Ile Pro Ser Ser Pro Glu Lys Pro Thr Pro Asn Gly Gly Ile
                 500                 505                 510

 Pro His Asp Asn Leu Val Leu Ile Arg Met Lys Pro Asp Glu Asn
                 515                 520                 525

 Gly Arg Phe Gly Phe Asn Val Lys Gly Gly Tyr Asp Gln Lys Met
                 530                 535                 540

 Pro Val Ile Val Ser Arg Val Ala Pro Gly Thr Pro Ala Asp Leu
                 545                 550                 555

 Cys Val Pro Arg Leu Asn Glu Gly Asp Gln Val Val Leu Ile Asn
                 560                 565                 570

 Gly Arg Asp Ile Ala Glu His Thr His Asp Gln Val Val Leu Phe
                 575                 580                 585

 Ile Lys Ala Ser Cys Glu Arg His Ser Gly Glu Leu Met Leu Leu
                 590                 595                 600

 Val Arg Pro Asn Ala Val Tyr Asp Val Val Glu Glu Lys Leu Glu
                 605                 610                 615

 Asn Glu Pro Asp Phe Gln Tyr Ile Pro Glu Lys Ala Pro Leu Asp
                 620                 625                 630

 Ser Val His Gln Asp Asp His Ser Leu Arg Glu Ser Met Ile Gln
                 635                 640                 645

 Leu Ala Glu Gly Leu Ile Thr Gly Thr Val Leu Thr Gln Phe Asp
                 650                 655                 660

 Gln Leu Tyr Arg Lys Lys Pro Gly Met Thr Met Ser Cys Ala Lys
                 665                 670                 675

 Leu Pro Gln Asn Ile Ser Lys Asn Arg Tyr Arg Asp Ile Ser Pro
                 680                 685                 690

 Tyr Asp Ala Thr Arg Val Ile Leu Lys Gly Asn Glu Asp Tyr Ile
                 695                 700                 705

 Asn Ala Asn Tyr Ile Asn Met Glu Ile Pro Ser Ser Ser Ile Ile
                 710                 715                 720

 Asn Gln Tyr Ile Ala Cys Gln Gly Pro Leu Pro His Thr Cys Thr
                 725                 730                 735

 Asp Phe Trp Gln Met Thr Trp Glu Gln Gly Ser Ser Met Val Val
                 740                 745                 750

 Met Leu Thr Thr Gln Val Glu Arg Gly Arg Val Lys Cys His Gln
                 755                 760                 765

 Tyr Trp Pro Glu Pro Thr Gly Ser Ser Ser Tyr Gly Cys Tyr Gln
                 770                 775                 780

 Val Thr Cys His Ser Glu Glu Gly Asn Thr Ala Tyr Ile Phe Arg
                 785                 790                 795

 Lys Met Thr Leu Phe Asn Gln Glu Lys Asn Glu Ser Arg Pro Leu
                 800                 805                 810

 Thr Gln Ile Gln Tyr Ile Ala Trp Pro Asp His Gly Val Pro Asp
                 815                 820                 825

 Asp Ser Ser Asp Phe Leu Asp Phe Val Cys His Val Arg Asn Lys
                 830                 835                 840

 Arg Ala Gly Lys Glu Glu Pro Val Val Val His Cys Ser Ala Gly
                 845                 850                 855

 Ile Gly Arg Thr Gly Val Leu Ile Thr Met Glu Thr Ala Met Cys
                 860                 865                 870

 Leu Ile Glu Cys Asn Gln Pro Val Tyr Pro Leu Asp Ile Val Arg
                 875                 880                 885

 Thr Met Arg Asp Gln Arg Ala Met Met Ile Gln Thr Pro Ser Gln
                 890                 895                 900

 Tyr Arg Phe Val Cys Glu Ala Ile Leu Lys Val Tyr Glu Glu Gly
                 905                 910                 915

 Phe Val Lys Pro Leu Thr Thr Ser Thr Asn Lys
                 920                 925

<210> 1305
<211> 1040
<212> DNA
<213> Homo sapien

<400> 1305
 cgacgagcca tggttgctgg gagcgacgcg gggcgggccc tgggggtcct 50

 cagcgtggtc tgcctgctgc actgctttgg tttcatcagc tgtttttccc 100

 aacaaatata tggtgttgtg tatgggaatg taactttcca tgtaccaagc 150

 aatgtgcctt taaaagaggt cctatggaaa aaacaaaagg ataaagttgc 200

 agaactggaa aattctgaat tcagagcttt ctcatctttt aaaaataggg 250

 tttatttaga cactgtgtca ggtagcctca ctatctacaa cttaacatca 300

 tcagatgaag atgagtatga aatggaatcg ccaaatatta ctgataccat 350

 gaagttcttt ctttatgtgc ttgagtctct tccatctccc acactaactt 400

 gtgcattgac taatggaagc attgaagtcc aatgcatgat accagagcat 450

 tacaacagcc atcgaggact tataatgtac tcatgggatt gtcctatgga 500

 gcaatgtaaa cgtaactcaa ccagtatata ttttaagatg gaaaatgatc 550

 ttccacaaaa aatacagtgt actcttagca atccattatt taatacaaca 600

 tcatcaatca ttttgacaac ctgtatccca agcagcggtc attcaagaca 650

 cagatatgca cttataccca taccattagc agtaattaca acatgtattg 700

 tgctgtatat gaatggtatt ctgaaatgtg acagaaaacc agacagaacc 750

 aactccaatt gattggtaac agaagatgaa gacaacagca taactaaatt 800

 attttaaaaa ctaaaaagcc atctgatttc tcatttgagt attacaattt 850

 ttgaacaact gttggaaatg taacttgaag cagctgcttt aagaagaaat 900

 acccactaac aaagaacaag cattagtttt ggctgtcatc aacttattat 950

 atgactaggt gcttgctttt tttgtcagta aattgttttt actgatgatg 1000

 tagatacttt tgtaaataaa tgtaaatatg tacacaagtg 1040

<210> 1306
<211> 250
<212> PRT
<213> Homo sapien

<400> 1306
 Met Val Ala Gly Ser Asp Ala Gly Arg Ala Leu Gly Val Leu Ser
   1               5                  10                  15

 Val Val Cys Leu Leu His Cys Phe Gly Phe Ile Ser Cys Phe Ser
                  20                  25                  30

 Gln Gln Ile Tyr Gly Val Val Tyr Gly Asn Val Thr Phe His Val
                  35                  40                  45

 Pro Ser Asn Val Pro Leu Lys Glu Val Leu Trp Lys Lys Gln Lys
                  50                  55                  60

 Asp Lys Val Ala Glu Leu Glu Asn Ser Glu Phe Arg Ala Phe Ser
                  65                  70                  75

 Ser Phe Lys Asn Arg Val Tyr Leu Asp Thr Val Ser Gly Ser Leu
                  80                  85                  90

 Thr Ile Tyr Asn Leu Thr Ser Ser Asp Glu Asp Glu Tyr Glu Met
                  95                 100                 105

 Glu Ser Pro Asn Ile Thr Asp Thr Met Lys Phe Phe Leu Tyr Val
                 110                 115                 120

 Leu Glu Ser Leu Pro Ser Pro Thr Leu Thr Cys Ala Leu Thr Asn
                 125                 130                 135

 Gly Ser Ile Glu Val Gln Cys Met Ile Pro Glu His Tyr Asn Ser
                 140                 145                 150

 His Arg Gly Leu Ile Met Tyr Ser Trp Asp Cys Pro Met Glu Gln
                 155                 160                 165

 Cys Lys Arg Asn Ser Thr Ser Ile Tyr Phe Lys Met Glu Asn Asp
                 170                 175                 180

 Leu Pro Gln Lys Ile Gln Cys Thr Leu Ser Asn Pro Leu Phe Asn
                 185                 190                 195

 Thr Thr Ser Ser Ile Ile Leu Thr Thr Cys Ile Pro Ser Ser Gly
                 200                 205                 210

 His Ser Arg His Arg Tyr Ala Leu Ile Pro Ile Pro Leu Ala Val
                 215                 220                 225

 Ile Thr Thr Cys Ile Val Leu Tyr Met Asn Gly Ile Leu Lys Cys
                 230                 235                 240

 Asp Arg Lys Pro Asp Arg Thr Asn Ser Asn
                 245                 250

<210> 1307
<211> 1734
<212> DNA
<213> Homo sapien

<400> 1307
 cggtgccaca gggacgaggc ctggagagca gtcgctccta gaaccggggc 50

 gcgaagggca cccccgcctc cagcacgcgc cctccgccct cccggcctcg 100

 ctccccccgg agtgggggcc tcgccggccc ctggtccccg tcactcagca 150

 acgtcgggtc agccttcgcc gggttagtgg cgacgcggcc gcgcgaattc 200

 gcacaggggc agtagaatga aagagggcat gtctaataac agcaccacta 250

 gcatctccca agccaggaaa gctgtggagc agctaaagat ggaagcctgt 300

 atggacaggg tcaaggtctc ccaggcagct gcggacctcc tggcctactg 350

 tgaagctcac gtgcgggaag atcctctcat cattccagtg cctgcatcag 400

 aaaacccctt tcgcgagaag aagttctttt gtaccattct ctaactccgt 450

 gtgtgatgaa aacgcctcct tttctgacct tcaaagtccc ctgtagagac 500

 catgcatgct ctaaacctta gggagtgaga ccaacaccca tccctgccca 550

 gccagagtgg ccggggcttg tcttatgttt ccatctgttt tcttcgtggc 600

 attcaatttc atttttttcc ttttcatttt catgttattt tcattattgg 650

 caaagaaaat caaaatgttt atagccaaat aacaaatgtg ccatgtaaaa 700

 gtaagtctgg acttaagagt ttaaaatttt taaacatcag tttccaagtt 750

 tatatcatat taatacattt cagtggataa tttatttaaa aaaaaaaact 800

 atgcctaaat atcccttatt tgcaatattc agtatcaaat tagagcattt 850

 tgaccaactg aaacatataa cgttttcatc tcctttcctg gagaaagcag 900

 ctgcagaggt tctgtatttc ctgcatttcc atcatcctag taaaaagaca 950

 acaacccaca ggattggaat ggttttcttt tgtttttttt ttgttgttgt 1000

 tgttgttttg agatggagtc tcgctctgtc acccaggctg gagtgcaatg 1050

 gcgtgacctc agctcactgc gacctccacc tcctgggttc aagcgattct 1100

 cctgcctcag cctcctgagt agctgggatc ataggcacgc gccaccacac 1150

 ccagctaatt ttttgtattt ttagtaaaga cggggtttca ccatgttggt 1200

 caggctggtc tcaaactcct gacctcgtga tccacccgcc tcggcctccc 1250

 aaagcgctgg gattacaggc gtgagccacc acacccggcc gtggaatggt 1300

 tttcttagca tatcctcctg gggccgtggc gcccaggctg tgggccgtgg 1350

 tggatgtccc ttgtttcagt ggtcctacaa aggtagatgg tgggcggaca 1400

 ccgaagtcaa cttgactgta aaagtacccc ataccgttga cgcgctgtgg 1450

 cagacctgtg ggtgcggtct cccctctcca aatgccacct cttcctgctc 1500

 cctcctcttt tggctcctac tcagtagttc cattgtgggc tgcagtaata 1550

 taaggacctg ttctggacac agcactgggc ccgctggggt tttagtaggg 1600

 cagccccttc cctgcaggag tgaggcatgg tgacagcagt cccctatgtg 1650

 cccccaagtc atctgagcat tggtgtgcat taaggtactc aatcttccaa 1700

 caataaatac cataagtgca aaaaaaaaaa aaaa 1734

<210> 1308
<211> 75
<212> PRT
<213> Homo sapien

<400> 1308
 Met Lys Glu Gly Met Ser Asn Asn Ser Thr Thr Ser Ile Ser Gln
   1               5                  10                  15

 Ala Arg Lys Ala Val Glu Gln Leu Lys Met Glu Ala Cys Met Asp
                  20                  25                  30

 Arg Val Lys Val Ser Gln Ala Ala Ala Asp Leu Leu Ala Tyr Cys
                  35                  40                  45

 Glu Ala His Val Arg Glu Asp Pro Leu Ile Ile Pro Val Pro Ala
                  50                  55                  60

 Ser Glu Asn Pro Phe Arg Glu Lys Lys Phe Phe Cys Thr Ile Leu
                  65                  70                  75

<210> 1309
<211> 2494
<212> DNA
<213> Homo sapien

<400> 1309
 ggggtgagag ctcctcctag gacacccctt tccccttggg gaaagaattg 50

 tgcccccagg cccttccccg cggaggtccc tctcctcctt ccccctcatc 100

 tccccttcct gggacagaaa gtgcctccac ctgcatcccc aggggcccgg 150

 cctccagggc ccgctggccc cacagcaggc aagctgagat gacggtcaag 200

 ctggatttcg aggagtgtct caaggactca ccccgtttcc gagcctctat 250

 tgagctggtg gaagccgaag tgtcagaatt ggagacccgt ctggaaaagc 300

 tcctgaaact gggcactggt ctcctggaaa gtgggcgcca ttaccttgct 350

 gccagccgcg ccttcgttgt cggcatttgt gacctggccc gcctgggtcc 400

 accagagccc atgatggcgg agtgtctgga aaaattcacc gtgagcctga 450

 accacaagct ggacagccat gcggagcttc tagatgccac ccaacacaca 500

 ctgcagcagc agatccagac cctggtcaag gaaggtctgc ggggtttccg 550

 agaggctcgc cgggatttct ggcggggggc tgagagcctg gaggctgccc 600

 tgacccacaa cgcagaggtt cccaggcgcc gggcccagga ggcagaagag 650

 gcaggagctg ctttgaggac ggctcgagct gggtaccggg gacgggcact 700

 ggattatgcc ctgcagatca acgtgattga ggacaagagg aagtttgaca 750

 tcatggagtt tgtgctgcgt ttggtggagg cccaggctac ccatttccag 800

 cagggccatg aggagctgag ccggctgtcc cagtatcgaa aggagctggg 850

 cgcccagttg caccagctgg tcttgaattc agcacgagag aagagggaca 900

 tggagcagag acacgtgctg ctgaaacaga aggagctggg tggggaggag 950

 ccagaaccaa gcttaagaga ggggcctggt ggcctggtga tggaaggaca 1000

 tctcttcaaa cgggccagca acgcatttaa gacctggagc agacgctggt 1050

 tcaccattca gagcaaccaa ctggtttacc agaagaagta caaggaccct 1100

 gtgactgtgg tggtggatga ccttcgtctc tgcacagtga aactctgccc 1150

 tgactcagaa aggcggttct gctttgaggt ggtgtccacc agcaagtcct 1200

 gcctcctcca ggctgactca gagcgcctcc tgcagctgtg ggtcagtgct 1250

 gtgcagagca gcattgcttc tgccttcagt caggctcgcc ttgatgacag 1300

 cccccggggt ccaggccagg gctcaggaca cctggccata ggctctgctg 1350

 ccaccctggg ctctggtgga atggccaggg gaagggagcc tgggggagtc 1400

 gggcacgtgg tggcccaggt ccagagtgtg gatggcaatg cccagtgctg 1450

 cgactgccgg gagccagccc cggagtgggc cagcatcaac cttggtgtca 1500

 ccctctgcat tcagtgttcc ggcatccaca ggagccttgg tgttcacttc 1550

 tccaaagtcc ggtctctgac ccttgactca tgggagccag aactagtgaa 1600

 gctcatgtgt gagctgggaa atgtcatcat caaccagatc tatgaggccc 1650

 gcgtggaggc catggcagtg aagaaaccag ggcccagctg ctcccggcag 1700

 gagaaggagg cctggattca cgctaaatac gtggagaaga agttcctgac 1750

 caagctgcct gagattcgag ggcgaagagg tggccggggg cgcccaaggg 1800

 ggcagcctcc tgtgccccca aagccttcca tcaggccccg gccagggagc 1850

 ttgagatcca agccagagcc cccctctgag gacctgggaa gcctgcaccc 1900

 tggggcccta ctgtttcgag cgtctgggca tcctccatct cttcccacca 1950

 tggctgatgc ccttgcccat ggagctgatg tcaactgggt caatgggggc 2000

 caagataatg ccacaccgct gatccaggcc acagctgcta attctcttct 2050

 ggcctgtgag tttctcctcc agaacggggc gaacgtgaac caagcggaca 2100

 gtgcgggccg gggcccgctg caccacgcaa ccattcttgg ccacacgggg 2150

 ctcgcctgcc tgttcctgaa acggggagct gatctggggg ctcgagactc 2200

 tgaaggcagg gaccctctga ccatcgccat ggaaacagcc aacgctgaca 2250

 tcgtcaccct gctacgactg gcaaagatga gggaggctga agcggcccag 2300

 gggcaggcag gagatgagac gtatcttgac atcttccgcg acttctccct 2350

 catggcgtca gacgacccgg agaagctgag ccgtcgcagt catgacctcc 2400

 acacgctgtg acccgaggcc cacggggccc gcgcctgcct cccttccccg 2450

 ccaccgggcc ctctgccatt aaagcctccg tgcttcgctc ttcc 2494

<210> 1310
<211> 740
<212> PRT
<213> Homo sapien

<400> 1310
 Met Thr Val Lys Leu Asp Phe Glu Glu Cys Leu Lys Asp Ser Pro
   1               5                  10                  15

 Arg Phe Arg Ala Ser Ile Glu Leu Val Glu Ala Glu Val Ser Glu
                  20                  25                  30

 Leu Glu Thr Arg Leu Glu Lys Leu Leu Lys Leu Gly Thr Gly Leu
                  35                  40                  45

 Leu Glu Ser Gly Arg His Tyr Leu Ala Ala Ser Arg Ala Phe Val
                  50                  55                  60

 Val Gly Ile Cys Asp Leu Ala Arg Leu Gly Pro Pro Glu Pro Met
                  65                  70                  75

 Met Ala Glu Cys Leu Glu Lys Phe Thr Val Ser Leu Asn His Lys
                  80                  85                  90

 Leu Asp Ser His Ala Glu Leu Leu Asp Ala Thr Gln His Thr Leu
                  95                 100                 105

 Gln Gln Gln Ile Gln Thr Leu Val Lys Glu Gly Leu Arg Gly Phe
                 110                 115                 120

 Arg Glu Ala Arg Arg Asp Phe Trp Arg Gly Ala Glu Ser Leu Glu
                 125                 130                 135

 Ala Ala Leu Thr His Asn Ala Glu Val Pro Arg Arg Arg Ala Gln
                 140                 145                 150

 Glu Ala Glu Glu Ala Gly Ala Ala Leu Arg Thr Ala Arg Ala Gly
                 155                 160                 165

 Tyr Arg Gly Arg Ala Leu Asp Tyr Ala Leu Gln Ile Asn Val Ile
                 170                 175                 180

 Glu Asp Lys Arg Lys Phe Asp Ile Met Glu Phe Val Leu Arg Leu
                 185                 190                 195

 Val Glu Ala Gln Ala Thr His Phe Gln Gln Gly His Glu Glu Leu
                 200                 205                 210

 Ser Arg Leu Ser Gln Tyr Arg Lys Glu Leu Gly Ala Gln Leu His
                 215                 220                 225

 Gln Leu Val Leu Asn Ser Ala Arg Glu Lys Arg Asp Met Glu Gln
                 230                 235                 240

 Arg His Val Leu Leu Lys Gln Lys Glu Leu Gly Gly Glu Glu Pro
                 245                 250                 255

 Glu Pro Ser Leu Arg Glu Gly Pro Gly Gly Leu Val Met Glu Gly
                 260                 265                 270

 His Leu Phe Lys Arg Ala Ser Asn Ala Phe Lys Thr Trp Ser Arg
                 275                 280                 285

 Arg Trp Phe Thr Ile Gln Ser Asn Gln Leu Val Tyr Gln Lys Lys
                 290                 295                 300

 Tyr Lys Asp Pro Val Thr Val Val Val Asp Asp Leu Arg Leu Cys
                 305                 310                 315

 Thr Val Lys Leu Cys Pro Asp Ser Glu Arg Arg Phe Cys Phe Glu
                 320                 325                 330

 Val Val Ser Thr Ser Lys Ser Cys Leu Leu Gln Ala Asp Ser Glu
                 335                 340                 345

 Arg Leu Leu Gln Leu Trp Val Ser Ala Val Gln Ser Ser Ile Ala
                 350                 355                 360

 Ser Ala Phe Ser Gln Ala Arg Leu Asp Asp Ser Pro Arg Gly Pro
                 365                 370                 375

 Gly Gln Gly Ser Gly His Leu Ala Ile Gly Ser Ala Ala Thr Leu
                 380                 385                 390

 Gly Ser Gly Gly Met Ala Arg Gly Arg Glu Pro Gly Gly Val Gly
                 395                 400                 405

 His Val Val Ala Gln Val Gln Ser Val Asp Gly Asn Ala Gln Cys
                 410                 415                 420

 Cys Asp Cys Arg Glu Pro Ala Pro Glu Trp Ala Ser Ile Asn Leu
                 425                 430                 435

 Gly Val Thr Leu Cys Ile Gln Cys Ser Gly Ile His Arg Ser Leu
                 440                 445                 450

 Gly Val His Phe Ser Lys Val Arg Ser Leu Thr Leu Asp Ser Trp
                 455                 460                 465

 Glu Pro Glu Leu Val Lys Leu Met Cys Glu Leu Gly Asn Val Ile
                 470                 475                 480

 Ile Asn Gln Ile Tyr Glu Ala Arg Val Glu Ala Met Ala Val Lys
                 485                 490                 495

 Lys Pro Gly Pro Ser Cys Ser Arg Gln Glu Lys Glu Ala Trp Ile
                 500                 505                 510

 His Ala Lys Tyr Val Glu Lys Lys Phe Leu Thr Lys Leu Pro Glu
                 515                 520                 525

 Ile Arg Gly Arg Arg Gly Gly Arg Gly Arg Pro Arg Gly Gln Pro
                 530                 535                 540

 Pro Val Pro Pro Lys Pro Ser Ile Arg Pro Arg Pro Gly Ser Leu
                 545                 550                 555

 Arg Ser Lys Pro Glu Pro Pro Ser Glu Asp Leu Gly Ser Leu His
                 560                 565                 570

 Pro Gly Ala Leu Leu Phe Arg Ala Ser Gly His Pro Pro Ser Leu
                 575                 580                 585

 Pro Thr Met Ala Asp Ala Leu Ala His Gly Ala Asp Val Asn Trp
                 590                 595                 600

 Val Asn Gly Gly Gln Asp Asn Ala Thr Pro Leu Ile Gln Ala Thr
                 605                 610                 615

 Ala Ala Asn Ser Leu Leu Ala Cys Glu Phe Leu Leu Gln Asn Gly
                 620                 625                 630

 Ala Asn Val Asn Gln Ala Asp Ser Ala Gly Arg Gly Pro Leu His
                 635                 640                 645

 His Ala Thr Ile Leu Gly His Thr Gly Leu Ala Cys Leu Phe Leu
                 650                 655                 660

 Lys Arg Gly Ala Asp Leu Gly Ala Arg Asp Ser Glu Gly Arg Asp
                 665                 670                 675

 Pro Leu Thr Ile Ala Met Glu Thr Ala Asn Ala Asp Ile Val Thr
                 680                 685                 690

 Leu Leu Arg Leu Ala Lys Met Arg Glu Ala Glu Ala Ala Gln Gly
                 695                 700                 705

 Gln Ala Gly Asp Glu Thr Tyr Leu Asp Ile Phe Arg Asp Phe Ser
                 710                 715                 720

 Leu Met Ala Ser Asp Asp Pro Glu Lys Leu Ser Arg Arg Ser His
                 725                 730                 735

 Asp Leu His Thr Leu
                 740

<210> 1311
<211> 1627
<212> DNA
<213> Homo sapien

<400> 1311
 ctccgctgct gtcgccagga gtcacttcac gagaagccag gtcacaaccg 50

 tcggcccttg tctggaaaag taaaagtgga tcctgccacg ttcggagctc 100

 cctggcgcct cgcccggctg gagctagaga actcgtcctg tggcggcccc 150

 cggcgtgggg cgggacagcg gccccctgga gggggcagtc ccgggagaac 200

 ctgcggcggc cggagcggta aaaataagtg actaaagaag cagacctggg 250

 aatcacctaa catgtcgagg aggagatttg attgccgaag tatttcaggc 300

 ctactaacta caactcctca aattccaata aaaatggaaa actttaataa 350

 tttctatata cttacatcta aagagctagg gagaggaaaa tttgctgtgg 400

 ttagacaatg tatatcaaaa tctactggcc aagaatatgc tgcaaaattt 450

 ctaaaaaaga gaagaagagg acaggattgt cgggcagaaa ttttacacga 500

 gattgctgtg cttgaattgg caaagtcttg tccccgtgtt attaatcttc 550

 atgaggtcta tgaaaataca agtgaaatca ttttgatatt ggaatatgct 600

 gcaggtggag aaattttcag cctgtgttta cctgagttgg ctgaaatggt 650

 ttctgaaaat gatgttatca gactcattaa acaaatactt gaaggagttt 700

 attatctaca tcagaataac attgtacacc ttgatttaaa gccacagaat 750

 atattactga gcagcatata ccctctcggg gacattaaaa tagtagattt 800

 tggaatgtct cgaaaaatag ggcatgcgtg tgaacttcgg gaaatcatgg 850

 gaacaccaga atatttagct ccagaaatcc tgaactatga tcccattacc 900

 acagcaacag atatgtggaa tattggtata atagcatata tgttgttaac 950

 tcacacatca ccatttgtgg gagaagataa tcaagaaaca tacctcaata 1000

 tttctcaagt taatgtagat tattcggaag aaactttttc atcagtttca 1050

 cagctggcca cagactttat tcagagcctt ttagtaaaaa atccagagaa 1100

 aagaccaaca gcagagatat gcctttctca ttcttggcta cagcagtggg 1150

 actttgaaaa cttgtttcac cctgaagaaa cttccagttc ctctcaaact 1200

 caggatcatt ctgtaaggtc ctctgaagac aagacttcta aatcctcctg 1250

 taatggaacc tgtggtgata gagaagacaa agagaatatc ccagaggata 1300

 gcagcatggt ttccaaaaga tttcgtttcg atgactcatt acccaatccc 1350

 catgaacttg tttcagattt gctctgttag cacttttttc tttgactcat 1400

 ttggactgaa tttgaaattt tatatccact ccagtgagat tatgatttgt 1450

 agcttcatat atgacatgtt tatattgtaa atgcactttt ccatggaata 1500

 atttagggaa gtgttttaat gttaaattac tagttgctag catgttatga 1550

 tttcatatcc tgagatagct ctgcagataa gaaaatattt aaatatatga 1600

 caaaaagtaa aattgtacat gtgaaag 1627

<210> 1312
<211> 372
<212> PRT
<213> Homo sapien

<400> 1312
 Met Ser Arg Arg Arg Phe Asp Cys Arg Ser Ile Ser Gly Leu Leu
   1               5                  10                  15

 Thr Thr Thr Pro Gln Ile Pro Ile Lys Met Glu Asn Phe Asn Asn
                  20                  25                  30

 Phe Tyr Ile Leu Thr Ser Lys Glu Leu Gly Arg Gly Lys Phe Ala
                  35                  40                  45

 Val Val Arg Gln Cys Ile Ser Lys Ser Thr Gly Gln Glu Tyr Ala
                  50                  55                  60

 Ala Lys Phe Leu Lys Lys Arg Arg Arg Gly Gln Asp Cys Arg Ala
                  65                  70                  75

 Glu Ile Leu His Glu Ile Ala Val Leu Glu Leu Ala Lys Ser Cys
                  80                  85                  90

 Pro Arg Val Ile Asn Leu His Glu Val Tyr Glu Asn Thr Ser Glu
                  95                 100                 105

 Ile Ile Leu Ile Leu Glu Tyr Ala Ala Gly Gly Glu Ile Phe Ser
                 110                 115                 120

 Leu Cys Leu Pro Glu Leu Ala Glu Met Val Ser Glu Asn Asp Val
                 125                 130                 135

 Ile Arg Leu Ile Lys Gln Ile Leu Glu Gly Val Tyr Tyr Leu His
                 140                 145                 150

 Gln Asn Asn Ile Val His Leu Asp Leu Lys Pro Gln Asn Ile Leu
                 155                 160                 165

 Leu Ser Ser Ile Tyr Pro Leu Gly Asp Ile Lys Ile Val Asp Phe
                 170                 175                 180

 Gly Met Ser Arg Lys Ile Gly His Ala Cys Glu Leu Arg Glu Ile
                 185                 190                 195

 Met Gly Thr Pro Glu Tyr Leu Ala Pro Glu Ile Leu Asn Tyr Asp
                 200                 205                 210

 Pro Ile Thr Thr Ala Thr Asp Met Trp Asn Ile Gly Ile Ile Ala
                 215                 220                 225

 Tyr Met Leu Leu Thr His Thr Ser Pro Phe Val Gly Glu Asp Asn
                 230                 235                 240

 Gln Glu Thr Tyr Leu Asn Ile Ser Gln Val Asn Val Asp Tyr Ser
                 245                 250                 255

 Glu Glu Thr Phe Ser Ser Val Ser Gln Leu Ala Thr Asp Phe Ile
                 260                 265                 270

 Gln Ser Leu Leu Val Lys Asn Pro Glu Lys Arg Pro Thr Ala Glu
                 275                 280                 285

 Ile Cys Leu Ser His Ser Trp Leu Gln Gln Trp Asp Phe Glu Asn
                 290                 295                 300

 Leu Phe His Pro Glu Glu Thr Ser Ser Ser Ser Gln Thr Gln Asp
                 305                 310                 315

 His Ser Val Arg Ser Ser Glu Asp Lys Thr Ser Lys Ser Ser Cys
                 320                 325                 330

 Asn Gly Thr Cys Gly Asp Arg Glu Asp Lys Glu Asn Ile Pro Glu
                 335                 340                 345

 Asp Ser Ser Met Val Ser Lys Arg Phe Arg Phe Asp Asp Ser Leu
                 350                 355                 360

 Pro Asn Pro His Glu Leu Val Ser Asp Leu Leu Cys
                 365                 370

<210> 1313
<211> 1216
<212> DNA
<213> Homo sapien

<400> 1313
 ttcggcactt gggagaagat gtttgaaaaa actgactctg ctaatgagcc 50

 tggactcaga gctcaagtct gaactctacc tccagacaga atgaagttca 100

 tctcgacatc tctgcttctc atgctgctgg tcagcagcct ctctccagtc 150

 caaggtgttc tggaggtcta ttacacaagc ttgaggtgta gatgtgtcca 200

 agagagctca gtctttatcc ctagacgctt cattgatcga attcaaatct 250

 tgccccgtgg gaatggttgt ccaagaaaag aaatcatagt ctggaagaag 300

 aacaagtcaa ttgtgtgtgt ggaccctcaa gctgaatgga tacaaagaat 350

 gatggaagta ttgagaaaaa gaagttcttc aactctacca gttccagtgt 400

 ttaagagaaa gattccctga tgctgatatt tccactaaga acacctgcat 450

 tcttccctta tccctgctct ggattttagt tttgtgctta gttaaatctt 500

 ttccagggag aaagaacttc cccatacaaa taaggcatga ggactatgtg 550

 aaaaataacc ttgcaggagc tgatggggca aactcaagct tcttcactca 600

 cagcacccta tatacacttg gagtttgcat tcttattcat cagggaggaa 650

 agtttctttg aaaatagtta ttcagttata agtaatacag gattattttg 700

 attatatact tgttgtttaa tgtttaaaat ttcttagaaa acaatggaat 750

 gagaatttaa gcctcaaatt tgaacatgtg gcttgaatta agaagaaaat 800

 tatggcatat attaaaagca ggcttctatg aaagactcaa aaagctgcct 850

 gggaggcaga tggaacttga gcctgtcaag aggcaaagga atccatgtag 900

 tagatatcct ctgcttaaaa actcactacg gaggagaatt aagtcctact 950

 tttaaagaat ttctttataa aatttactgt ctaagattaa tagcattcga 1000

 agatccccag acttcataga atactcaggg aaagcattta aagggtgatg 1050

 tacacatgta tcctttcaca catttgcctt gacaaacttc tttcactcac 1100

 atctttttca ctgacttttt ttgtgggggc ggggccgggg ggactctggt 1150

 atctaattct ttaatgattc ctataaatct aatgacattc aataaagttg 1200

 agcaaacatt ttactt 1216

<210> 1314
<211> 109
<212> PRT
<213> Homo sapien

<400> 1314
 Met Lys Phe Ile Ser Thr Ser Leu Leu Leu Met Leu Leu Val Ser
   1               5                  10                  15

 Ser Leu Ser Pro Val Gln Gly Val Leu Glu Val Tyr Tyr Thr Ser
                  20                  25                  30

 Leu Arg Cys Arg Cys Val Gln Glu Ser Ser Val Phe Ile Pro Arg
                  35                  40                  45

 Arg Phe Ile Asp Arg Ile Gln Ile Leu Pro Arg Gly Asn Gly Cys
                  50                  55                  60

 Pro Arg Lys Glu Ile Ile Val Trp Lys Lys Asn Lys Ser Ile Val
                  65                  70                  75

 Cys Val Asp Pro Gln Ala Glu Trp Ile Gln Arg Met Met Glu Val
                  80                  85                  90

 Leu Arg Lys Arg Ser Ser Ser Thr Leu Pro Val Pro Val Phe Lys
                  95                 100                 105

 Arg Lys Ile Pro


<210> 1315
<211> 2910
<212> DNA
<213> Homo sapien

<400> 1315
 gcccaggtga ctgactaatc cgccgccttc aggagacaga attggccaag 50

 gcctgaaggc cccggagtgc accagcggca tgtacaaaga gaccgtctac 100

 tccgccttca atctgctcat gcattaccca cccccctcgg gagcagggca 150

 gcacccccag ccgcagcccc cgctgcacaa ggccaatcag cccccccacg 200

 gtgtccccca actctctctc tacgaacatt tcaacagccc acatcccacc 250

 cctgcacctg cggacatcag ccagaagcaa gttcacaggc ctctgcagac 300

 ccctgacctc tctggcttct actccctgac ctcaggcagc atggggcagc 350

 tcccccacac tgtgagctgg ttcacccacc catccttgat gctaggttct 400

 ggtgtacctg gtcacccagc agccatcccc cacccggcca ttgtgccccc 450

 ctcagggaag caggagctgc agcccttcga ccgcaacctg aagacacaag 500

 cagagtccaa ggcagagaag gaggccaaga agccaaccat caagaagccc 550

 ctcaatgcct tcatgctgta catgaaggag atgagagcca aggtcattgc 600

 agagtgcaca cttaaggaga gcgctgccat caaccagatc ctgggccgca 650

 ggtggcacgc gctgtcgcga gaagagcagg ccaagtacta tgagctggcc 700

 cgcaaggaga ggcagctgca catgcagcta tacccaggct ggtcagcgcg 750

 ggacaactac gggaagaaga agaggcggtc gagggaaaag caccaagaat 800

 ccaccacaga ccctggctcg cctaagaaat gccgtgctcg ctttggcctc 850

 aaccagcaga cggattggtg tggtccgtgc agataactct cttcactatt 900

 cctaggagga aaaagaaatg cattcggtac ttacccggag aaggccgctg 950

 ccccagcccc gttccttccg atgacagtgc tctaggctgc cccgggtccc 1000

 cagctcccca ggactcaccc tcataccatc tgctgccccg cttccccaca 1050

 gaactgctta ctagccctgc ggagcggcac ctacatcccc aggtctctcc 1100

 actgctctca gcctcccaac cccagggccc ccacaggccc cccgcagcac 1150

 cctgcagagc acacaggtac agcaacagga atctcagaga caggtggcct 1200

 agcaggcaca ggacacctgg ccgcctccag gagcctaccc cctgaaaatg 1250

 acagagaccc agatctcatg gaaactggca ggggtcctgt taacgtcatc 1300

 tcagggtcca gaccctgaag atttcagagg ctgcagaact tctgcctgaa 1350

 cctggggtca tcgattcaaa ctgctccaag tggtgggaat cagatctgtc 1400

 ttgatgtgtc atctaattaa gggaatccct tgtacctatg actccgtcga 1450

 tctattcttt gtaccatctg tcttgccagc cagaagcctc tgcctcccta 1500

 gcttttctgc tataggtcag agatgggctg aactgagcct agctaccttc 1550

 tctacccatc tcccccatcc cccactgcca caccctcccc attcagacac 1600

 ttcatggacc aagaatgagc tggtttgtca aacaacatgt gagcatggtc 1650

 acaagcacaa agctcaagat gacagctctt ctaaggaaat ggagaagctc 1700

 tgtttataaa aacaaaaaca aaaccagctg ctactcataa gttggaccag 1750

 aggaagcccc ttactatgat ctcaggagct tgcaagaagc aggaagggga 1800

 atggaatagg ttaagtttag gcctatcaac ctaagcaaca gaaataatct 1850

 gacactacct tatcaggcaa attggggagg ggagggtgta tctagctcta 1900

 gttcaaatta tttggaagtg ttccctgaga aacccaccag cctaagaagc 1950

 tctggcccca ggcttgtcac tagcagctgc agtcaacagt tcaaagaagt 2000

 catggcccaa atccagtgtg cacccctccc cattcacaga gcctttttca 2050

 caattccatt tccagttcat ctatggcagt ccagccagct tctgggcagc 2100

 ttgagagggc aaacccaaaa cctcatgaca gccagagcct gtctttcagc 2150

 attcagtcgc ctgggaagct ccagtttccc catggggctg cgggacagag 2200

 gaccattaca actagatcaa ggagcccaga aaacctccag tagtggacaa 2250

 caggttttca ccatagccta cgttaaccca tttttgagcc aagcttcaac 2300

 cctcagcctt gaaaaacaag tctttaattt aatttttgtt ttttgcctaa 2350

 atccaaagaa aaagggctgc cgggccaggc gcggtcgtca cgcctgtaat 2400

 cccagcactt tggcaggccg aggcaggtgg atcacctgac gtcagtagtt 2450

 tgagaccagc ctggccaaca tggtgaaacc ctgtatctac taaaaataca 2500

 aaaattagcc ggacgtggtg gtgcgcgcat gtaatcccag ctactcggga 2550

 ggctgaggcg gaagaatcac ttgaacccgg gaggcggagg ttccagtgag 2600

 ccgagatggc gctattgcac tccagtctgg gtaacaggga gactgcatct 2650

 caaaaaaaaa aaaaaaaaaa aagggctgtc catgtattca cacacccctc 2700

 aaaaaaagcc tttagttcct actttagcca ctggtttctc agaatccaaa 2750

 gatcacatat tctagtgtaa cactgcaaga agtcttgaga aaaagattat 2800

 tgtagtgttc aaaatatttt tgtattgtta atgcatcatc atagaaaaac 2850

 ttttaaacat gagaataaag atacttttta ctgggtttgt ttttcaaagc 2900

 ctgaaaaaaa 2910

<210> 1316
<211> 268
<212> PRT
<213> Homo sapien

<400> 1316
 Met Tyr Lys Glu Thr Val Tyr Ser Ala Phe Asn Leu Leu Met His
   1               5                  10                  15

 Tyr Pro Pro Pro Ser Gly Ala Gly Gln His Pro Gln Pro Gln Pro
                  20                  25                  30

 Pro Leu His Lys Ala Asn Gln Pro Pro His Gly Val Pro Gln Leu
                  35                  40                  45

 Ser Leu Tyr Glu His Phe Asn Ser Pro His Pro Thr Pro Ala Pro
                  50                  55                  60

 Ala Asp Ile Ser Gln Lys Gln Val His Arg Pro Leu Gln Thr Pro
                  65                  70                  75

 Asp Leu Ser Gly Phe Tyr Ser Leu Thr Ser Gly Ser Met Gly Gln
                  80                  85                  90

 Leu Pro His Thr Val Ser Trp Phe Thr His Pro Ser Leu Met Leu
                  95                 100                 105

 Gly Ser Gly Val Pro Gly His Pro Ala Ala Ile Pro His Pro Ala
                 110                 115                 120

 Ile Val Pro Pro Ser Gly Lys Gln Glu Leu Gln Pro Phe Asp Arg
                 125                 130                 135

 Asn Leu Lys Thr Gln Ala Glu Ser Lys Ala Glu Lys Glu Ala Lys
                 140                 145                 150

 Lys Pro Thr Ile Lys Lys Pro Leu Asn Ala Phe Met Leu Tyr Met
                 155                 160                 165

 Lys Glu Met Arg Ala Lys Val Ile Ala Glu Cys Thr Leu Lys Glu
                 170                 175                 180

 Ser Ala Ala Ile Asn Gln Ile Leu Gly Arg Arg Trp His Ala Leu
                 185                 190                 195

 Ser Arg Glu Glu Gln Ala Lys Tyr Tyr Glu Leu Ala Arg Lys Glu
                 200                 205                 210

 Arg Gln Leu His Met Gln Leu Tyr Pro Gly Trp Ser Ala Arg Asp
                 215                 220                 225

 Asn Tyr Gly Lys Lys Lys Arg Arg Ser Arg Glu Lys His Gln Glu
                 230                 235                 240

 Ser Thr Thr Asp Pro Gly Ser Pro Lys Lys Cys Arg Ala Arg Phe
                 245                 250                 255

 Gly Leu Asn Gln Gln Thr Asp Trp Cys Gly Pro Cys Arg
                 260                 265

<210> 1317
<211> 2910
<212> DNA
<213> Homo sapien

<400> 1317
 gcccaggtga ctgactaatc cgccgccttc aggagacaga attggccaag 50

 gcctgaaggc cccggagtgc accagcggca tgtacaaaga gaccgtctac 100

 tccgccttca atctgctcat gcattaccca cccccctcgg gagcagggca 150

 gcacccccag ccgcagcccc cgctgcacaa ggccaatcag cccccccacg 200

 gtgtccccca actctctctc tacgaacatt tcaacagccc acatcccacc 250

 cctgcacctg cggacatcag ccagaagcaa gttcacaggc ctctgcagac 300

 ccctgacctc tctggcttct actccctgac ctcaggcagc atggggcagc 350

 tcccccacac tgtgagctgg ttcacccacc catccttgat gctaggttct 400

 ggtgtacctg gtcacccagc agccatcccc cacccggcca ttgtgccccc 450

 ctcagggaag caggagctgc agcccttcga ccgcaacctg aagacacaag 500

 cagagtccaa ggcagagaag gaggccaaga agccaaccat caagaagccc 550

 ctcaatgcct tcatgctgta catgaaggag atgagagcca aggtcattgc 600

 agagtgcaca cttaaggaga gcgctgccat caaccagatc ctgggccgca 650

 ggtggcacgc gctgtcgcga gaagagcagg ccaagtacta tgagctggcc 700

 cgcaaggaga ggcagctgca catgcagcta tacccaggct ggtcagcgcg 750

 ggacaactac gggaagaaga agaggcggtc gagggaaaag caccaagaat 800

 ccaccacaga ccctggctcg cctaagaaat gccgtgctcg ctttggcctc 850

 aaccagcaga cggattggtg tggtccgtgc agataactct cttcactatt 900

 cctaggagga aaaagaaatg cattcggtac ttacccggag aaggccgctg 950

 ccccagcccc gttccttccg atgacagtgc tctaggctgc cccgggtccc 1000

 cagctcccca ggactcaccc tcataccatc tgctgccccg cttccccaca 1050

 gaactgctta ctagccctgc ggagcggcac ctacatcccc aggtctctcc 1100

 actgctctca gcctcccaac cccagggccc ccacaggccc cccgcagcac 1150

 cctgcagagc acacaggtac agcaacagga atctcagaga caggtggcct 1200

 agcaggcaca ggacacctgg ccgcctccag gagcctaccc cctgaaaatg 1250

 acagagaccc agatctcatg gaaactggca ggggtcctgt taacgtcatc 1300

 tcagggtcca gaccctgaag atttcagagg ctgcagaact tctgcctgaa 1350

 cctggggtca tcgattcaaa ctgctccaag tggtgggaat cagatctgtc 1400

 ttgatgtgtc atctaattaa gggaatccct tgtacctatg actccgtcga 1450

 tctattcttt gtaccatctg tcttgccagc cagaagcctc tgcctcccta 1500

 gcttttctgc tataggtcag agatgggctg aactgagcct agctaccttc 1550

 tctacccatc tcccccatcc cccactgcca caccctcccc attcagacac 1600

 ttcatggacc aagaatgagc tggtttgtca aacaacatgt gagcatggtc 1650

 acaagcacaa agctcaagat gacagctctt ctaaggaaat ggagaagctc 1700

 tgtttataaa aacaaaaaca aaaccagctg ctactcataa gttggaccag 1750

 aggaagcccc ttactatgat ctcaggagct tgcaagaagc aggaagggga 1800

 atggaatagg ttaagtttag gcctatcaac ctaagcaaca gaaataatct 1850

 gacactacct tatcaggcaa attggggagg ggagggtgta tctagctcta 1900

 gttcaaatta tttggaagtg ttccctgaga aacccaccag cctaagaagc 1950

 tctggcccca ggcttgtcac tagcagctgc agtcaacagt tcaaagaagt 2000

 catggcccaa atccagtgtg cacccctccc cattcacaga gcctttttca 2050

 caattccatt tccagttcat ctatggcagt ccagccagct tctgggcagc 2100

 ttgagagggc aaacccaaaa cctcatgaca gccagagcct gtctttcagc 2150

 attcagtcgc ctgggaagct ccagtttccc catggggctg cgggacagag 2200

 gaccattaca actagatcaa ggagcccaga aaacctccag tagtggacaa 2250

 caggttttca ccatagccta cgttaaccca tttttgagcc aagcttcaac 2300

 cctcagcctt gaaaaacaag tctttaattt aatttttgtt ttttgcctaa 2350

 atccaaagaa aaagggctgc cgggccaggc gcggtcgtca cgcctgtaat 2400

 cccagcactt tggcaggccg aggcaggtgg atcacctgac gtcagtagtt 2450

 tgagaccagc ctggccaaca tggtgaaacc ctgtatctac taaaaataca 2500

 aaaattagcc ggacgtggtg gtgcgcgcat gtaatcccag ctactcggga 2550

 ggctgaggcg gaagaatcac ttgaacccgg gaggcggagg ttccagtgag 2600

 ccgagatggc gctattgcac tccagtctgg gtaacaggga gactgcatct 2650

 caaaaaaaaa aaaaaaaaaa aagggctgtc catgtattca cacacccctc 2700

 aaaaaaagcc tttagttcct actttagcca ctggtttctc agaatccaaa 2750

 gatcacatat tctagtgtaa cactgcaaga agtcttgaga aaaagattat 2800

 tgtagtgttc aaaatatttt tgtattgtta atgcatcatc atagaaaaac 2850

 ttttaaacat gagaataaag atacttttta ctgggtttgt ttttcaaagc 2900

 ctgaaaaaaa 2910

<210> 1318
<211> 268
<212> PRT
<213> Homo sapien

<400> 1318
 Met Tyr Lys Glu Thr Val Tyr Ser Ala Phe Asn Leu Leu Met His
   1               5                  10                  15

 Tyr Pro Pro Pro Ser Gly Ala Gly Gln His Pro Gln Pro Gln Pro
                  20                  25                  30

 Pro Leu His Lys Ala Asn Gln Pro Pro His Gly Val Pro Gln Leu
                  35                  40                  45

 Ser Leu Tyr Glu His Phe Asn Ser Pro His Pro Thr Pro Ala Pro
                  50                  55                  60

 Ala Asp Ile Ser Gln Lys Gln Val His Arg Pro Leu Gln Thr Pro
                  65                  70                  75

 Asp Leu Ser Gly Phe Tyr Ser Leu Thr Ser Gly Ser Met Gly Gln
                  80                  85                  90

 Leu Pro His Thr Val Ser Trp Phe Thr His Pro Ser Leu Met Leu
                  95                 100                 105

 Gly Ser Gly Val Pro Gly His Pro Ala Ala Ile Pro His Pro Ala
                 110                 115                 120

 Ile Val Pro Pro Ser Gly Lys Gln Glu Leu Gln Pro Phe Asp Arg
                 125                 130                 135

 Asn Leu Lys Thr Gln Ala Glu Ser Lys Ala Glu Lys Glu Ala Lys
                 140                 145                 150

 Lys Pro Thr Ile Lys Lys Pro Leu Asn Ala Phe Met Leu Tyr Met
                 155                 160                 165

 Lys Glu Met Arg Ala Lys Val Ile Ala Glu Cys Thr Leu Lys Glu
                 170                 175                 180

 Ser Ala Ala Ile Asn Gln Ile Leu Gly Arg Arg Trp His Ala Leu
                 185                 190                 195

 Ser Arg Glu Glu Gln Ala Lys Tyr Tyr Glu Leu Ala Arg Lys Glu
                 200                 205                 210

 Arg Gln Leu His Met Gln Leu Tyr Pro Gly Trp Ser Ala Arg Asp
                 215                 220                 225

 Asn Tyr Gly Lys Lys Lys Arg Arg Ser Arg Glu Lys His Gln Glu
                 230                 235                 240

 Ser Thr Thr Asp Pro Gly Ser Pro Lys Lys Cys Arg Ala Arg Phe
                 245                 250                 255

 Gly Leu Asn Gln Gln Thr Asp Trp Cys Gly Pro Cys Arg
                 260                 265

<210> 1319
<211> 3868
<212> DNA
<213> Homo sapien

<400> 1319
 atgaacctct gaaaactgcc ggcatctgag gtttcctcca aggccctctg 50

 aagtgcagcc cataatgaag gtcttggcgg caggagttgt gcccctgctg 100

 ttggttctgc actggaaaca tggggcgggg agccccctcc ccatcacccc 150

 tgtcaacgcc acctgtgcca tacgccaccc atgtcacaac aacctcatga 200

 accagatcag gagccaactg gcacagctca atggcagtgc caatgccctc 250

 tttattctct attacacagc ccagggggag ccgttcccca acaacctgga 300

 caagctatgt ggccccaacg tgacggactt cccgcccttc cacgccaacg 350

 gcacggagaa ggccaagctg gtggagctgt accgcatagt cgtgtacctt 400

 ggcacctccc tgggcaacat cacccgggac cagaagatcc tcaaccccag 450

 tgccctcagc ctccacagca agctcaacgc caccgccgac atcctgcgag 500

 gcctccttag caacgtgctg tgccgcctgt gcagcaagta ccacgtgggc 550

 catgtggacg tgacctacgg ccctgacacc tcgggtaagg atgtcttcca 600

 gaagaagaag ctgggctgtc aactcctggg gaagtataag cagatcatcg 650

 ccgtgttggc ccaggccttc tagcaggagg tcttgaagtg tgctgtgaac 700

 cgagggatct caggagttgg gtccagatgt gggggcctgt ccaagggtgg 750

 ctggggccca gggcatcgct aaacccaaat gggggctgct ggcagacccc 800

 gagggtgcct ggccagtcca ctccactctg ggctgggctg tgatgaagct 850

 gagcagagtg gaaacttcca tagggaggga gctagaagaa ggtgcccctt 900

 cctctgggag attgtggact ggggagcgtg ggctggactt ctgcctctac 950

 ttgtcccttt ggccccttgc tcactttgtg cagtgaacaa actacacaag 1000

 tcatctacaa gagccctgac cacagggtga gacagcaggg cccaggggag 1050

 tggaccagcc cccagcaaat tatcaccatc tgtgcctttg ctgcccctta 1100

 ggttgggact taggtgggcc agaggggcta ggatcccaaa ggactccttg 1150

 tcccctagaa gtttgatgag tggaagatag agaggggcct ctgggatgga 1200

 aggctgtctt cttttgagga tgatcagaga acttgggcat aggaacaatc 1250

 tggcagaagt ttccagaagg aggtcacttg gcattcaggc tcttggggag 1300

 gcagagaagc caccttcagg cctgggaagg aagacactgg gaggaggaga 1350

 ggcctggaaa gctttggtag gttcttcgtt ctcttccccg tgatcttccc 1400

 tgcagcctgg gatggccagg gtctgatggc tggacctgca gcaggggttt 1450

 gtggaggtgg gtagggcagg ggcaggttgc taagtcaggt gcagaggttc 1500

 tgagggaccc aggctcttcc tctgggtaaa ggtctgtaag aaggggctgg 1550

 ggtagctcag agtagcagct cacatctgag gccctgggag gtcttgtgag 1600

 gtcacacaga ggtacttgag ggggactgga ggccgtctct ggtccccagg 1650

 gcaagggaac agcagaactt agggtcaggg tctcagggaa ccctgagctc 1700

 caagcgtgct gtgcgtctga cctggcatga tttctattta ttatgatatc 1750

 ctatttatat taacttattg gtgctttcag tggccaagtt aattcccctt 1800

 tccctggtcc ctactcaaca aaatatgatg atggctcccg acacaagcgc 1850

 cagggccagg gcttagcagg gcctggtctg gaagtcgaca atgttacaag 1900

 tggaataagc ttacgggtga agctcagaga agggtcggat ctgagagaat 1950

 ggggaggcct gagtgggagt ggggggcctt gctccacccc catcccctac 2000

 tgtgacttgc tttagcgtgt cagggtccag gctgcagggg ctgggccaat 2050

 ttgtggagag gccgggtgcc tttctgtctt gcttccaggg ggctggttca 2100

 cactgttctt gggcgcccca gcattgtgtt gtgaggcgca ctgttcctgg 2150

 cagatattgt gccccctgga gcagtgggca agacagtcct tgtggcccac 2200

 cctgtccttg tttctgtgtc cccatgctgc ctctgaaata gcgccctgga 2250

 acaaccctgc ccctgcaccc agcatgctcc gacacagcag ggaagctcct 2300

 cctgtggccc ggacacccat agacggtgcg gggggcctgg ctgggccaga 2350

 ccccaggaag gtggggtaga ctggggggat cagctgccca ttgctcccaa 2400

 gaggaggaga gggaggctgc agacgcctgg gactcagacc aggaagctgt 2450

 gggccctcct gctccacccc catcccactc ccacccatgt ctgggctccc 2500

 aggcagggaa cccgatctct tcctttgtgc tggggccagg cgagtggaga 2550

 aacgccctcc agtctgagag caggggaggg aaggaggcag cagagttggg 2600

 gcagctgctc agagcagtgt tctggcttct tctcaaaccc tgagcgggct 2650

 gccggcctcc aagttcctcc gacaagatga tggtactaat tatggtactt 2700

 ttcactcact ttgcaccttt ccctgtcgct ctctaagcac tttacctgga 2750

 tggcgcgtgg gcagtgtgca ggcaggtcct gaggcctggg gttggggtgg 2800

 agggtgcggc ccggagttgt ccatctgtcc atcccaacag caagacgagg 2850

 atgtggctgt tgagatgtgg gccacactca cccttgtcca ggatgcaggg 2900

 actgccttct ccttcctgct tcatccggct tagcttgggg ctggctgcat 2950

 tcccccagga tgggcttcga gaaagacaaa cttgtctgga aaccagagtt 3000

 gctgattcca cccggggggc ccggctgact cgcccatcac ctcatctccc 3050

 tgtggacttg ggagctctgt gccaggccca ccttgcggcc ctggctctga 3100

 gtcgctctcc cacccagcct ggacttggcc ccatgggacc catcctcagt 3150

 gctccctcca gatcccgtcc ggcagcttgg cgtccaccct gcacagcatc 3200

 actgaatcac agagcctttg cgtgaaacag ctctgccagg ccgggagctg 3250

 ggtttctctt ccctttttat ctgctggtgt ggaccacacc tgggcctggc 3300

 cggaggaaga gagagtttac caagagagat gtctccgggc ccttatttat 3350

 tatttaaaca tttttttaaa aagcactgct agtttacttg tctctcctcc 3400

 ccatcgtccc catcgtcctc cttgtccctg acttggggca cttccaccct 3450

 gacccagcca gtccagctct gccttgccgg ctctccagag tagacatagt 3500

 gtgtggggtt ggagctctgg cacccgggga ggtagcattt ccctgcagat 3550

 ggtacagatg ttcctgcctt agagtcatct ctagttcccc acctcaatcc 3600

 cggcatccag ccttcagtcc cgcccacgtg ctagctccgt gggcccaccg 3650

 tgcggcctta gaggtttccc tccttccttt ccactgaaaa gcacatggcc 3700

 ttgggtgaca aattcctctt tgatgaatgt accctgtggg gatgtttcat 3750

 actgacagat tatttttatt tattcaatgt catatttaaa atatttattt 3800

 tttataccaa atgaatcact ttttttttta agaaaaaaaa gagaaatgaa 3850

 taaagaatct actcttcg 3868

<210> 1320
<211> 202
<212> PRT
<213> Homo sapien

<400> 1320
 Met Lys Val Leu Ala Ala Gly Val Val Pro Leu Leu Leu Val Leu
   1               5                  10                  15

 His Trp Lys His Gly Ala Gly Ser Pro Leu Pro Ile Thr Pro Val
                  20                  25                  30

 Asn Ala Thr Cys Ala Ile Arg His Pro Cys His Asn Asn Leu Met
                  35                  40                  45

 Asn Gln Ile Arg Ser Gln Leu Ala Gln Leu Asn Gly Ser Ala Asn
                  50                  55                  60

 Ala Leu Phe Ile Leu Tyr Tyr Thr Ala Gln Gly Glu Pro Phe Pro
                  65                  70                  75

 Asn Asn Leu Asp Lys Leu Cys Gly Pro Asn Val Thr Asp Phe Pro
                  80                  85                  90

 Pro Phe His Ala Asn Gly Thr Glu Lys Ala Lys Leu Val Glu Leu
                  95                 100                 105

 Tyr Arg Ile Val Val Tyr Leu Gly Thr Ser Leu Gly Asn Ile Thr
                 110                 115                 120

 Arg Asp Gln Lys Ile Leu Asn Pro Ser Ala Leu Ser Leu His Ser
                 125                 130                 135

 Lys Leu Asn Ala Thr Ala Asp Ile Leu Arg Gly Leu Leu Ser Asn
                 140                 145                 150

 Val Leu Cys Arg Leu Cys Ser Lys Tyr His Val Gly His Val Asp
                 155                 160                 165

 Val Thr Tyr Gly Pro Asp Thr Ser Gly Lys Asp Val Phe Gln Lys
                 170                 175                 180

 Lys Lys Leu Gly Cys Gln Leu Leu Gly Lys Tyr Lys Gln Ile Ile
                 185                 190                 195

 Ala Val Leu Ala Gln Ala Phe
                 200

<210> 1321
<211> 3314
<212> DNA
<213> Homo sapien

<400> 1321
 gaattccggc aggcgcccat ggcgggctga gtcctgccca tgccctggtg 50

 gcctggaagc ctgcatgggc gccgtgcaaa gatcaacgtt ttccagagga 100

 gcttttgggc tcatcactgg cctggggagg gcttgacacg gggttcccac 150

 agcttgcccc acaccacctt cacacccaca cacagcaggt ccccgcgggg 200

 ccggtgcagg ctgtggctgc ccgcgctgcg ctgttgctct gtcccggctg 250

 gctggctccg agtgtggggc gctctgggcc ggggccgctg gggcgcgcac 300

 agtggggtga caggcggcct ggctgcagaa acgttgcacc ggtgcctgag 350

 gtgggaggat gtgatgacgc ggcccacgca gcgggaaccc aggcctttaa 400

 aaagcccagg aaacagcctc agctcaagcg gtggctccac tggaggaaaa 450

 cacaccccgg tctcacatta aagaagccaa actgtcggct tcaaagagaa 500

 aaggcaacat cctgtcacag gccatgctct ggcaaaaacc cacagctccg 550

 gagcaagccc cagccccggc ccggccatac cagggcgtcc gtgtgaagga 600

 gccagtgaag gaactgctga ggaggaagcg aggccacgcc agcagtgggg 650

 cagcacctgc acctacggcg gtggtgctgc cccatcagcc cctggcgacc 700

 tacaccacag tgggtccttc ctgcctggac atggaaggtt ctgtgtctgc 750

 agtgacagag gaggctgccc tgtgtgccgg ctggctctcc cagcccaccc 800

 cggccaccct gcagcccctg gccccatgga caccttacac cgagtatgtg 850

 ccccatgaag ctgtcagctg cccctactca gctgacatgt atgtgcagcc 900

 cgtgtgcccc agctacacgg tggtggggcc ctcctcagtg ttggcctatg 950

 cctctccgcc actcatcacc aatgtcacga caagaagctc cgccacgccc 1000

 gcagtggggc ccccgctgga gggcccagag caccaggcac ccctcaccta 1050

 tttcccgtgg cctcagcccc tttccacact acccacctcc accctgcagt 1100

 accggcctcc ggccccagcc ctacctgggc cccagtttgt ccagctcccc 1150

 atctctatcc cagagccagt ccttcaggac atggaagacc ccagaagagc 1200

 cgccagctcg ttgaccatcg acaagctgct tttggaggaa gaggatagcg 1250

 acgcctatgc gcttaaccac actctctctg tggaaggctt ttaggcgtgg 1300

 ctcccacctg agtcctgttc cctgaaactg ggattttaaa atgagcctgg 1350

 aattgagccc caggttcatg cttgtttgga gtagtcattt catgactact 1400

 ctttctacgc acagctagaa ttgtagacct gtaaaccttc cttcccttct 1450

 tccttcccct ccctccctca cttcctccct ctcccccatc cttccattct 1500

 tcccctccct cccttcttcc tttccaaccc cttccttcct tttcctccct 1550

 cccttccttc cctccttccc ttctcccttt ccaacccctt ccttcctttt 1600

 cctccctccc ttccttccct ccttcccttc tccctttcct tctttacctc 1650

 cctccctccc tcgcttcttc tctctttctt acttcttttt tcaattctgt 1700

 tccattttgg gaggtaatta tagggatttt agcaataaca ttttatgtca 1750

 aatgttgcca agtctgtggt ccatgggctt tcatttctgt cacatttcat 1800

 ttcttggaaa aggcctcctt cctccagtgc ctgctgaacc atcttagggt 1850

 cactcacacc ctctgtaatt ttaagatgta tgtggtggcc ggcgggaaga 1900

 ccagccccga cagcacctcc tgagaaagtc agccaagggc ctaccctgat 1950

 gccagagtcc ttgagctgtc agttcccaca gttgctcctt tgtttgctct 2000

 tctcagcctc ggccagattt acagtccagg cagcaaaatc tcaaggcctg 2050

 gggctcagag tagtaagggg tgggaagtgg gtggcaggga gaaaagaaca 2100

 tcagggtggg tggggacagg ccagtgacga agagagggac agaggaggga 2150

 tgggaacagg ctgtgcatct tagttggaga gaggggtgtg ggaggaagct 2200

 tgagtttgat gcagggagga ggaaggctga ggaatgactt ggctccagat 2250

 tacttggtta ttaagaagaa caataaacta aaggaaagca ttgcttgaag 2300

 agatggtttt gctgctctcc ttgaggatac gtgcaaggga agttgggctg 2350

 ttgtaaacag ggtgaagggt gtgtttggtc ggccatttct ctctcacctc 2400

 taggccctct gctggtgctg tggaggccaa gaccccatta agcctaaagg 2450

 tgatgggtcc tcgcctaggc ttagtgctac catgtgggtt ttgtttcttt 2500

 ccttccttcc ttccttcctt ccttccttcc ttccttcctt ccttccttcc 2550

 ttccttcctt ccttctttcc ttccttcctt ccttccttcc ttcctctctc 2600

 tttctttctt ttttttggtt ttttttggga cggagtctca ctccattgcc 2650

 caggctggag tacaatggtg cgatcttggc tcactgcacc tctgtctccc 2700

 aagttcaagt gattctcctg cctgagcctc ccgagtagct gggattacag 2750

 gtgcatgcca ccatgcctgg ctaatttttg tatttttagt agagacgggg 2800

 tttcaccatg ttggccaggc tggtctcgaa ctcctgacct tgtgatccgc 2850

 gcgcctcagc ctctcagagt gctgggatca caggcgtgag ccaccgcacc 2900

 cagcctttta ccatgtgggt ttctttagtg tcttaaaagc gtccataagc 2950

 caccattctg tggaaccaag gccccctcca cgcaaacacc ctccctcctg 3000

 gggacctctg gagcctcagc cagaagtacc attaggttta attttaattt 3050

 gttttgctgg agaaacatca ggtttgtagg agactgagtt gttagcaggt 3100

 gtgcttagct cttgatagtg aacgtgtacc ttgggaactg gctcacccac 3150

 ctgctaatag caccatcgtc actattaagc agacatttca gttggtagaa 3200

 tccatgtaga agtcatggac ttttctggga aatgactttt ctgggaaatg 3250

 acagtttctt tgacatattt tctttgccca ctttaaataa aaactctgga 3300

 gaaaaaaaaa aaaa 3314

<210> 1322
<211> 256
<212> PRT
<213> Homo sapien

<400> 1322
 Met Leu Trp Gln Lys Pro Thr Ala Pro Glu Gln Ala Pro Ala Pro
   1               5                  10                  15

 Ala Arg Pro Tyr Gln Gly Val Arg Val Lys Glu Pro Val Lys Glu
                  20                  25                  30

 Leu Leu Arg Arg Lys Arg Gly His Ala Ser Ser Gly Ala Ala Pro
                  35                  40                  45

 Ala Pro Thr Ala Val Val Leu Pro His Gln Pro Leu Ala Thr Tyr
                  50                  55                  60

 Thr Thr Val Gly Pro Ser Cys Leu Asp Met Glu Gly Ser Val Ser
                  65                  70                  75

 Ala Val Thr Glu Glu Ala Ala Leu Cys Ala Gly Trp Leu Ser Gln
                  80                  85                  90

 Pro Thr Pro Ala Thr Leu Gln Pro Leu Ala Pro Trp Thr Pro Tyr
                  95                 100                 105

 Thr Glu Tyr Val Pro His Glu Ala Val Ser Cys Pro Tyr Ser Ala
                 110                 115                 120

 Asp Met Tyr Val Gln Pro Val Cys Pro Ser Tyr Thr Val Val Gly
                 125                 130                 135

 Pro Ser Ser Val Leu Ala Tyr Ala Ser Pro Pro Leu Ile Thr Asn
                 140                 145                 150

 Val Thr Thr Arg Ser Ser Ala Thr Pro Ala Val Gly Pro Pro Leu
                 155                 160                 165

 Glu Gly Pro Glu His Gln Ala Pro Leu Thr Tyr Phe Pro Trp Pro
                 170                 175                 180

 Gln Pro Leu Ser Thr Leu Pro Thr Ser Thr Leu Gln Tyr Arg Pro
                 185                 190                 195

 Pro Ala Pro Ala Leu Pro Gly Pro Gln Phe Val Gln Leu Pro Ile
                 200                 205                 210

 Ser Ile Pro Glu Pro Val Leu Gln Asp Met Glu Asp Pro Arg Arg
                 215                 220                 225

 Ala Ala Ser Ser Leu Thr Ile Asp Lys Leu Leu Leu Glu Glu Glu
                 230                 235                 240

 Asp Ser Asp Ala Tyr Ala Leu Asn His Thr Leu Ser Val Glu Gly
                 245                 250                 255

 Phe


<210> 1323
<211> 2400
<212> DNA
<213> Homo sapien

<400> 1323
 taggatggaa aggcagatgt aaagtccctc atggcgaaat ataacacggg 50

 gggcaacccg acagaggatg tctcagtcaa tagccgaccc ttcagagtca 100

 cagggccaaa ctcatcttca ggaatacaag caagaaagaa cttattcaac 150

 aaccaaggaa atgccagccc tcctgcagga cccagcaatg tacctaagtt 200

 tgggtcccca aagccacctg tggcagtcaa accttcttct gaggaaaagc 250

 ctgacaagga acccaagccc ccgtttctaa agcccactgg agcaggccaa 300

 agattcggaa caccagccag cttgaccacc agagaccccg aggcgaaagt 350

 gggatttctg aaacctgtag gccccaagcc catcaacttg cccaaagaag 400

 attccaaacc tacatttccc tggcctcctg gaaacaagcc atctcttcac 450

 agtgtaaacc aagaccatga cttaaagcca ctaggcccga aatctgggcc 500

 tactcctcca acctcagaaa atgaacagaa gcaagcgttt cccaaattga 550

 ctggggttaa agggaaattt atgtcagcat cacaagatct tgaacccaag 600

 cccctcttcc ccaaacccgc ctttggccag aagccgcccc taagtaccga 650

 gaactcccat gaagacgaaa gccccatgaa gaatgtgtct tcatcaaaag 700

 ggtccccagc tcccctggga gtcaggtcca aaagcggccc tttaaaacca 750

 gcaagggaag actcagaaaa taaagaccat gcaggggaga tttcaagttt 800

 gccctttcct ggagtggttt tgaaacctgc tgcgagcagg ggaggcctag 850

 gtctctccaa aaatggtgaa gaaaaaaagg aagataggaa gatagatgct 900

 gctaagaaca ccttccagag caaaataaat caggaagagt tggcctcagg 950

 gactcctcct gccaggttcc ctaaggcccc ttctaagctg acagtggggg 1000

 ggccatgggg ccaaagtcag gaaaaggaaa agggagacaa gaattcagcc 1050

 accccgaaac agaagccatt gcctcccttg tttaccttgg gtccacctcc 1100

 accaaaaccc aacagaccac caaatgttga cctgacgaaa ttccacaaaa 1150

 cctcttctgg aaacagtact agcaaaggcc agacgtctta ctcaacaact 1200

 tccctgccac cacctccacc atcccatccg gccagccaac caccattgcc 1250

 agcatctcac ccatcacaac caccagtccc aagcctacct cccagaaaca 1300

 ttaaacctcc gtttgaccta aaaagccctg tcaatgaaga caatcaagat 1350

 ggtgtcacgc actctgatgg tgctggaaat ctagatgagg aacaagacag 1400

 tgaaggagaa acatatgaag acatagaagc atccaaagaa agagagaaga 1450

 aaagggaaaa ggaagaaaag aagaggttag agctggagaa aaaggaacag 1500

 aaagagaaag aaaagaaaga acaagaaata aagaagaaat ttaaactaac 1550

 aggccctatt caagtcatcc atcttgcaaa agcttgttgt gatgtcaaag 1600

 gaggaaagaa tgaactgagc ttcaagcaag gagagcaaat tgaaatcatc 1650

 cgcatcacag acaacccaga aggaaaatgg ttgggcagaa cagcaagggg 1700

 ttcatatggc tatattaaaa caactgctgt agagattgac tatgattctt 1750

 tgaaactgaa aaaagactct cttggtgccc cttcaagacc tattgaagat 1800

 gaccaagaag tatatgatga tgttgcagag caggatgata ttagcagcca 1850

 cagtcagagt ggaagtggag ggatattccc tccaccacca gatgatgaca 1900

 tttatgatgg gattgaagag gaagatgctg atgatggttt ccctgctcct 1950

 cctaaacaat tggacatggg agatgaagtt tacgatgatg tggatacctc 2000

 tgatttccct gtttcatcag cagagatgag tcaaggaact aattttggaa 2050

 aagctaagac agaagaaaag gaccttaaga agctaaaaaa gcaggaaaaa 2100

 gaagaaaaag acttcaggaa aaaatttaaa tatgatggtg aaattagagt 2150

 cctatattca actaaagtta caacttccat aacttctaaa aagtggggaa 2200

 ccagagatct acaggtaaaa cctggtgaat ctctagaagt tatacaaacc 2250

 acagatgaca caaaagttct ctgcagaaat gaagaaggga aatatggtta 2300

 tgtccttcgg agttacctag cggacaatga tggagagatc tatgatgata 2350

 ttgctgatgg ctgcatctat gacaatgact agcactcaac tttggtcatt 2400

<210> 1324
<211> 783
<212> PRT
<213> Homo sapien

<400> 1324
 Met Ala Lys Tyr Asn Thr Gly Gly Asn Pro Thr Glu Asp Val Ser
   1               5                  10                  15

 Val Asn Ser Arg Pro Phe Arg Val Thr Gly Pro Asn Ser Ser Ser
                  20                  25                  30

 Gly Ile Gln Ala Arg Lys Asn Leu Phe Asn Asn Gln Gly Asn Ala
                  35                  40                  45

 Ser Pro Pro Ala Gly Pro Ser Asn Val Pro Lys Phe Gly Ser Pro
                  50                  55                  60

 Lys Pro Pro Val Ala Val Lys Pro Ser Ser Glu Glu Lys Pro Asp
                  65                  70                  75

 Lys Glu Pro Lys Pro Pro Phe Leu Lys Pro Thr Gly Ala Gly Gln
                  80                  85                  90

 Arg Phe Gly Thr Pro Ala Ser Leu Thr Thr Arg Asp Pro Glu Ala
                  95                 100                 105

 Lys Val Gly Phe Leu Lys Pro Val Gly Pro Lys Pro Ile Asn Leu
                 110                 115                 120

 Pro Lys Glu Asp Ser Lys Pro Thr Phe Pro Trp Pro Pro Gly Asn
                 125                 130                 135

 Lys Pro Ser Leu His Ser Val Asn Gln Asp His Asp Leu Lys Pro
                 140                 145                 150

 Leu Gly Pro Lys Ser Gly Pro Thr Pro Pro Thr Ser Glu Asn Glu
                 155                 160                 165

 Gln Lys Gln Ala Phe Pro Lys Leu Thr Gly Val Lys Gly Lys Phe
                 170                 175                 180

 Met Ser Ala Ser Gln Asp Leu Glu Pro Lys Pro Leu Phe Pro Lys
                 185                 190                 195

 Pro Ala Phe Gly Gln Lys Pro Pro Leu Ser Thr Glu Asn Ser His
                 200                 205                 210

 Glu Asp Glu Ser Pro Met Lys Asn Val Ser Ser Ser Lys Gly Ser
                 215                 220                 225

 Pro Ala Pro Leu Gly Val Arg Ser Lys Ser Gly Pro Leu Lys Pro
                 230                 235                 240

 Ala Arg Glu Asp Ser Glu Asn Lys Asp His Ala Gly Glu Ile Ser
                 245                 250                 255

 Ser Leu Pro Phe Pro Gly Val Val Leu Lys Pro Ala Ala Ser Arg
                 260                 265                 270

 Gly Gly Leu Gly Leu Ser Lys Asn Gly Glu Glu Lys Lys Glu Asp
                 275                 280                 285

 Arg Lys Ile Asp Ala Ala Lys Asn Thr Phe Gln Ser Lys Ile Asn
                 290                 295                 300

 Gln Glu Glu Leu Ala Ser Gly Thr Pro Pro Ala Arg Phe Pro Lys
                 305                 310                 315

 Ala Pro Ser Lys Leu Thr Val Gly Gly Pro Trp Gly Gln Ser Gln
                 320                 325                 330

 Glu Lys Glu Lys Gly Asp Lys Asn Ser Ala Thr Pro Lys Gln Lys
                 335                 340                 345

 Pro Leu Pro Pro Leu Phe Thr Leu Gly Pro Pro Pro Pro Lys Pro
                 350                 355                 360

 Asn Arg Pro Pro Asn Val Asp Leu Thr Lys Phe His Lys Thr Ser
                 365                 370                 375

 Ser Gly Asn Ser Thr Ser Lys Gly Gln Thr Ser Tyr Ser Thr Thr
                 380                 385                 390

 Ser Leu Pro Pro Pro Pro Pro Ser His Pro Ala Ser Gln Pro Pro
                 395                 400                 405

 Leu Pro Ala Ser His Pro Ser Gln Pro Pro Val Pro Ser Leu Pro
                 410                 415                 420

 Pro Arg Asn Ile Lys Pro Pro Phe Asp Leu Lys Ser Pro Val Asn
                 425                 430                 435

 Glu Asp Asn Gln Asp Gly Val Thr His Ser Asp Gly Ala Gly Asn
                 440                 445                 450

 Leu Asp Glu Glu Gln Asp Ser Glu Gly Glu Thr Tyr Glu Asp Ile
                 455                 460                 465

 Glu Ala Ser Lys Glu Arg Glu Lys Lys Arg Glu Lys Glu Glu Lys
                 470                 475                 480

 Lys Arg Leu Glu Leu Glu Lys Lys Glu Gln Lys Glu Lys Glu Lys
                 485                 490                 495

 Lys Glu Gln Glu Ile Lys Lys Lys Phe Lys Leu Thr Gly Pro Ile
                 500                 505                 510

 Gln Val Ile His Leu Ala Lys Ala Cys Cys Asp Val Lys Gly Gly
                 515                 520                 525

 Lys Asn Glu Leu Ser Phe Lys Gln Gly Glu Gln Ile Glu Ile Ile
                 530                 535                 540

 Arg Ile Thr Asp Asn Pro Glu Gly Lys Trp Leu Gly Arg Thr Ala
                 545                 550                 555

 Arg Gly Ser Tyr Gly Tyr Ile Lys Thr Thr Ala Val Glu Ile Asp
                 560                 565                 570

 Tyr Asp Ser Leu Lys Leu Lys Lys Asp Ser Leu Gly Ala Pro Ser
                 575                 580                 585

 Arg Pro Ile Glu Asp Asp Gln Glu Val Tyr Asp Asp Val Ala Glu
                 590                 595                 600

 Gln Asp Asp Ile Ser Ser His Ser Gln Ser Gly Ser Gly Gly Ile
                 605                 610                 615

 Phe Pro Pro Pro Pro Asp Asp Asp Ile Tyr Asp Gly Ile Glu Glu
                 620                 625                 630

 Glu Asp Ala Asp Asp Gly Phe Pro Ala Pro Pro Lys Gln Leu Asp
                 635                 640                 645

 Met Gly Asp Glu Val Tyr Asp Asp Val Asp Thr Ser Asp Phe Pro
                 650                 655                 660

 Val Ser Ser Ala Glu Met Ser Gln Gly Thr Asn Phe Gly Lys Ala
                 665                 670                 675

 Lys Thr Glu Glu Lys Asp Leu Lys Lys Leu Lys Lys Gln Glu Lys
                 680                 685                 690

 Glu Glu Lys Asp Phe Arg Lys Lys Phe Lys Tyr Asp Gly Glu Ile
                 695                 700                 705

 Arg Val Leu Tyr Ser Thr Lys Val Thr Thr Ser Ile Thr Ser Lys
                 710                 715                 720

 Lys Trp Gly Thr Arg Asp Leu Gln Val Lys Pro Gly Glu Ser Leu
                 725                 730                 735

 Glu Val Ile Gln Thr Thr Asp Asp Thr Lys Val Leu Cys Arg Asn
                 740                 745                 750

 Glu Glu Gly Lys Tyr Gly Tyr Val Leu Arg Ser Tyr Leu Ala Asp
                 755                 760                 765

 Asn Asp Gly Glu Ile Tyr Asp Asp Ile Ala Asp Gly Cys Ile Tyr
                 770                 775                 780

 Asp Asn Asp


<210> 1325
<211> 4262
<212> DNA
<213> Homo sapien

<400> 1325
 cgaagaggat ccggagcagc tgctgccagc ccgcgggcac tgaagtcctc 50

 ccggctgccg ctcgagtagc cacgggcgcg atcgggacca gaagtctcct 100

 cctccatgat cactttggaa gccggggggg aagactttgc cctgccctga 150

 gagctggtct gcgtttccca ggcgcggcgg cggcggagca gcagctgcag 200

 cagccgagtc caaataggag cggccacagc caggggcgtg tgcgccccgc 250

 gcggagcgag ctcgggttcc cctcggaatg tccccggggc gcccggcgcg 300

 ctgaccccga agccgcctcc gccttcggcg cctgctgcct ccctcggcca 350

 ggcttgttgt tcgggactgt gagcttcctg gctcctgggc agtggggaag 400

 cccccggggg cgagtgacct cagctggcca cgacccagcc ctcccccgtg 450

 cgtatctcgc ttaagatggc agcggagtca ggggaactaa tcggggcttg 500

 tgagttcatg aaagatcggt tatattttgc tactttaagg aatagaccaa 550

 aaagcacagt aaatacccac tatttctcca tcgatgagga gctggtctat 600

 gaaaatttct atgcagattt tggaccgctg aacttggcaa tggtgtacag 650

 atattgctgc aaactaaaca agaaactaaa atcatacagt ttgtcaagaa 700

 agaaaatagt gcactacacc tgttttgacc aacggaaaag agcaaatgca 750

 gcatttttga taggtgccta tgcagtaatc tatttaaaga agacaccaga 800

 agaagcctac agagcactcc tgtctggctc aaaccccccc tatcttccat 850

 tcagggatgc ttcctttgga aattgcactt acaatctcac cattctcgac 900

 tgtttgcagg gaatcagaaa gggattacaa catggatttt ttgactttga 950

 gacatttgat gtggatgaat atgaacatta tgagcgagtt gaaaatggtg 1000

 acttcaactg gattgttcca ggaaaatttt tagcatttag tggaccacat 1050

 cctaaaagca aaattgagaa tggttatcct cttcacgccc ctgaagccta 1100

 ctttccttat ttcaaaaagc ataatgtgac tgcagttgtg aggctaaaca 1150

 aaaagattta tgaggcaaag cgcttcacag acgctggctt cgagcactat 1200

 gacctcttct tcatagatgg cagcacaccc agtgacaaca tcgtgcgaag 1250

 gttcctgaac atctgtgaga acaccgaagg ggccatcgcc gttcactgca 1300

 aagctggtct tggaagaaca gggacattga tagcctgtta tgtaatgaaa 1350

 cactacaggt ttacacatgc tgaaataatt gcttggatta gaatatgccg 1400

 gccaggctct attataggac cccagcagca cttcctggaa gaaaaacaag 1450

 catcgttgtg ggtccaagga gacattttcc gatccaaact gaaaaatcga 1500

 ccatccagtg aaggaagtat taataaaatt ctttctggcc tagatgatat 1550

 gtctattggt ggaaatcttt caaaaacaca aaacatggaa cgatttggag 1600

 aggataactt agaagatgat gatgtggaaa tgaaaaatgg tataacccag 1650

 ggagacaaac tacgtgcctt aaaaagtcag agacagccac gtacctcacc 1700

 atcctgtgca tttaggtcag atgatacaaa aggacatcca agagcagtgt 1750

 cccagccttt cagattaagt tcatccctgc aaggatctgc agttactttg 1800

 aagacatcaa aaatggcact gtccccttca gcaacggcca agaggatcaa 1850

 cagaacttct ttgtcttcgg gtgccactgt aagaagcttt tccataaact 1900

 cccggctagc cagttctcta gggaacttga atgctgcaac agatgatcca 1950

 gagaacaaaa agacctcctc atcctctaag gcaggcttca cagccagccc 2000

 gtttaccaac ctcttgaatg gcagctccca gccaactacc agaaattacc 2050

 ctgagctcaa caataatcag tacaacagaa gcagcaacag caacgggggc 2100

 aacctgaaca gccccccagg cccccacagc gccaagacag aggagcacac 2150

 caccatcctc cgaccctcct acaccgggct ttcttcttct tcagcgagat 2200

 tcctgagccg ttctatccct tcccttcagt ctgaatatgt tcattactaa 2250

 ggccttgcca ctccagtgaa agctgttctt ctcttagaca caatttcttc 2300

 atctggacga gcagtggaga gggaaagcaa cttcttgctg gaagaatatc 2350

 tctgccttct taccttaaat taaaaagagc actaagataa caccttcaag 2400

 agacttgaaa acagaaaact ggttaatgac tactataaat gcactgaaac 2450

 tatgttatgg agatttccat acttttaaag acagttttaa tgttgaattt 2500

 ggtattttga agggttattt ttaatgtatt ttggtaatac atttattatt 2550

 atatttacat gtacagtgtt acattatata tgtattgtga actttaaaag 2600

 actattttga taaatttata aatatataaa attatgtaaa aactacacta 2650

 tattttgatt tagattttcc tgctgtttgc taccaaaaat ttgtatttta 2700

 aatctgttta gttttagtat ggttttgtct ctaatgaata aataattcct 2750

 tcttattaag aagaagtaag ggagaaagtt tttagaaagt gatttttatg 2800

 ctcgcactat aaatatggca ggtcagttca ttcttttggg aagtcagttt 2850

 agttacactg agtttatcca agtttatctc taccaagagt ataatggcat 2900

 gggatggctt atttaggaca attccctttc ctattgtttt tgttgctgag 2950

 ccaatttgag ttagttttgc atcctggggg gctttaaaat acagcatgca 3000

 gtgaaagatc agaattcact gaatatttct tctgagagca tggtttcatg 3050

 gtttttctct atgaaatgac tcaatattcc aaatgttttt ttttccttcc 3100

 tcctttcaaa agagttctta acccaattag gatatcctgc tttgggtatg 3150

 aggttgttgt tgcctgtaat cacacatggt ttgacatcag ttttaaatca 3200

 atggagagaa aaaactgaaa aagatgctgc taagtagttc tctgtattaa 3250

 aggagatatt tttaaaacag ggtacaaccc cctgctgcac acgctagcat 3300

 atctggaacc tactatgaaa atgaaaggac ccttataggt actcacagcc 3350

 ctttcatgta agtatgatct gatatttagg tcttcagaag cctgtaggtt 3400

 tcatttctat gaggaatcga ggagcgttac atcctgatat ccttccaggc 3450

 tgcttaagaa tggactgctt cgacactgaa agtgctagtt aaatggattc 3500

 atatgaagtg ctttactccc aaccattgag ttatttataa tgtatttatt 3550

 aggggagggt accttgagtc tattatatat gcttcatcaa aacatcttgt 3600

 tcatgtttta tgtttttaaa aaaggcattt gaatgaatgt ttgactcagg 3650

 tttgttaaat taacttcagt aactgcagta ccaaaaatta cactcaactg 3700

 atgaaaaaaa cgaattgtat gatttaggaa tcaaaaacta aaataagtgg 3750

 aattatgtat cttttctaaa gttaaaaaag taaaatattt tattatgagt 3800

 tattataaaa attggttaat tgtataggaa gatgacagta tttttttcaa 3850

 gttatcataa aaagtaattc agatgacatt tgagaagtag gggaaaggga 3900

 atcatgttga cagttttagt tctgtgaaca ctaatttgtg tgaagctatt 3950

 aaaatgattg taaagttgac tactgtaaat ttcccataat tatgtgtgta 4000

 tatgtgtcat atgtatgtac atgtatatgt ctaaaaatta ctttacacat 4050

 gtgcctacat agacacacca agaagtggat gtatataata tagaaagtat 4100

 atagcaaagt aattttactc tgataataaa aattgtttga catgtatttt 4150

 gttatgaata gtttatcttc caaaagatat tttgctctat tttaaagtgt 4200

 agaagaatac actgctaata aataataaaa gttttattca atttaaaaaa 4250

 aaaaaaaaaa aa 4262

<210> 1326
<211> 594
<212> PRT
<213> Homo sapien

<400> 1326
 Met Ala Ala Glu Ser Gly Glu Leu Ile Gly Ala Cys Glu Phe Met
   1               5                  10                  15

 Lys Asp Arg Leu Tyr Phe Ala Thr Leu Arg Asn Arg Pro Lys Ser
                  20                  25                  30

 Thr Val Asn Thr His Tyr Phe Ser Ile Asp Glu Glu Leu Val Tyr
                  35                  40                  45

 Glu Asn Phe Tyr Ala Asp Phe Gly Pro Leu Asn Leu Ala Met Val
                  50                  55                  60

 Tyr Arg Tyr Cys Cys Lys Leu Asn Lys Lys Leu Lys Ser Tyr Ser
                  65                  70                  75

 Leu Ser Arg Lys Lys Ile Val His Tyr Thr Cys Phe Asp Gln Arg
                  80                  85                  90

 Lys Arg Ala Asn Ala Ala Phe Leu Ile Gly Ala Tyr Ala Val Ile
                  95                 100                 105

 Tyr Leu Lys Lys Thr Pro Glu Glu Ala Tyr Arg Ala Leu Leu Ser
                 110                 115                 120

 Gly Ser Asn Pro Pro Tyr Leu Pro Phe Arg Asp Ala Ser Phe Gly
                 125                 130                 135

 Asn Cys Thr Tyr Asn Leu Thr Ile Leu Asp Cys Leu Gln Gly Ile
                 140                 145                 150

 Arg Lys Gly Leu Gln His Gly Phe Phe Asp Phe Glu Thr Phe Asp
                 155                 160                 165

 Val Asp Glu Tyr Glu His Tyr Glu Arg Val Glu Asn Gly Asp Phe
                 170                 175                 180

 Asn Trp Ile Val Pro Gly Lys Phe Leu Ala Phe Ser Gly Pro His
                 185                 190                 195

 Pro Lys Ser Lys Ile Glu Asn Gly Tyr Pro Leu His Ala Pro Glu
                 200                 205                 210

 Ala Tyr Phe Pro Tyr Phe Lys Lys His Asn Val Thr Ala Val Val
                 215                 220                 225

 Arg Leu Asn Lys Lys Ile Tyr Glu Ala Lys Arg Phe Thr Asp Ala
                 230                 235                 240

 Gly Phe Glu His Tyr Asp Leu Phe Phe Ile Asp Gly Ser Thr Pro
                 245                 250                 255

 Ser Asp Asn Ile Val Arg Arg Phe Leu Asn Ile Cys Glu Asn Thr
                 260                 265                 270

 Glu Gly Ala Ile Ala Val His Cys Lys Ala Gly Leu Gly Arg Thr
                 275                 280                 285

 Gly Thr Leu Ile Ala Cys Tyr Val Met Lys His Tyr Arg Phe Thr
                 290                 295                 300

 His Ala Glu Ile Ile Ala Trp Ile Arg Ile Cys Arg Pro Gly Ser
                 305                 310                 315

 Ile Ile Gly Pro Gln Gln His Phe Leu Glu Glu Lys Gln Ala Ser
                 320                 325                 330

 Leu Trp Val Gln Gly Asp Ile Phe Arg Ser Lys Leu Lys Asn Arg
                 335                 340                 345

 Pro Ser Ser Glu Gly Ser Ile Asn Lys Ile Leu Ser Gly Leu Asp
                 350                 355                 360

 Asp Met Ser Ile Gly Gly Asn Leu Ser Lys Thr Gln Asn Met Glu
                 365                 370                 375

 Arg Phe Gly Glu Asp Asn Leu Glu Asp Asp Asp Val Glu Met Lys
                 380                 385                 390

 Asn Gly Ile Thr Gln Gly Asp Lys Leu Arg Ala Leu Lys Ser Gln
                 395                 400                 405

 Arg Gln Pro Arg Thr Ser Pro Ser Cys Ala Phe Arg Ser Asp Asp
                 410                 415                 420

 Thr Lys Gly His Pro Arg Ala Val Ser Gln Pro Phe Arg Leu Ser
                 425                 430                 435

 Ser Ser Leu Gln Gly Ser Ala Val Thr Leu Lys Thr Ser Lys Met
                 440                 445                 450

 Ala Leu Ser Pro Ser Ala Thr Ala Lys Arg Ile Asn Arg Thr Ser
                 455                 460                 465

 Leu Ser Ser Gly Ala Thr Val Arg Ser Phe Ser Ile Asn Ser Arg
                 470                 475                 480

 Leu Ala Ser Ser Leu Gly Asn Leu Asn Ala Ala Thr Asp Asp Pro
                 485                 490                 495

 Glu Asn Lys Lys Thr Ser Ser Ser Ser Lys Ala Gly Phe Thr Ala
                 500                 505                 510

 Ser Pro Phe Thr Asn Leu Leu Asn Gly Ser Ser Gln Pro Thr Thr
                 515                 520                 525

 Arg Asn Tyr Pro Glu Leu Asn Asn Asn Gln Tyr Asn Arg Ser Ser
                 530                 535                 540

 Asn Ser Asn Gly Gly Asn Leu Asn Ser Pro Pro Gly Pro His Ser
                 545                 550                 555

 Ala Lys Thr Glu Glu His Thr Thr Ile Leu Arg Pro Ser Tyr Thr
                 560                 565                 570

 Gly Leu Ser Ser Ser Ser Ala Arg Phe Leu Ser Arg Ser Ile Pro
                 575                 580                 585

 Ser Leu Gln Ser Glu Tyr Val His Tyr
                 590

<210> 1327
<211> 2154
<212> DNA
<213> Homo sapien

<400> 1327
 gtcctttgac cagagttttt ccatgtggac gctctttcaa tggacgtgtc 50

 cccgcgtgct tcttagacgg actgcggtct cctaaaggtc gaccatggtg 100

 gccgggaccc gctgtcttct agcgttgctg cttccccagg tcctcctggg 150

 cggcgcggct ggcctcgttc cggagctggg ccgcaggaag ttcgcggcgg 200

 cgtcgtcggg ccgcccctca tcccagccct ctgacgaggt cctgagcgag 250

 ttcgagttgc ggctgctcag catgttcggc ctgaaacaga gacccacccc 300

 cagcagggac gccgtggtgc ccccctacat gctagacctg tatcgcaggc 350

 actcgggtca gccgggctca cccgccccag accaccggtt ggagagggca 400

 gccagccgag ccaacactgt gcgcagcttc caccatgaag aatctttgga 450

 agaactacca gaaacgagtg ggaaaacaac ccggagattc ttctttaatt 500

 taagttctat ccccacggag gagtttatca cctcagcaga gcttcaggtt 550

 ttccgagaac agatgcaaga tgctttagga aacaatagca gtttccatca 600

 ccgaattaat atttatgaaa tcataaaacc tgcaacagcc aactcgaaat 650

 tccccgtgac cagtcttttg gacaccaggt tggtgaatca gaatgcaagc 700

 aggtgggaaa gttttgatgt cacccccgct gtgatgcggt ggactgcaca 750

 gggacacgcc aaccatggat tcgtggtgga agtggcccac ttggaggaga 800

 aacaaggtgt ctccaagaga catgttagga taagcaggtc tttgcaccaa 850

 gatgaacaca gctggtcaca gataaggcca ttgctagtaa cttttggcca 900

 tgatggaaaa gggcatcctc tccacaaaag agaaaaacgt caagccaaac 950

 acaaacagcg gaaacgcctt aagtccagct gtaagagaca ccctttgtac 1000

 gtggacttca gtgacgtggg gtggaatgac tggattgtgg ctcccccggg 1050

 gtatcacgcc ttttactgcc acggagaatg cccttttcct ctggctgatc 1100

 atctgaactc cactaatcat gccattgttc agacgttggt caactctgtt 1150

 aactctaaga ttcctaaggc atgctgtgtc ccgacagaac tcagtgctat 1200

 ctcgatgctg taccttgacg agaatgaaaa ggttgtatta aagaactatc 1250

 aggacatggt tgtggagggt tgtgggtgtc gctagtacag caaaattaaa 1300

 tacataaata tatatatata tatatattct agaaaaaaga aaaaaacaaa 1350

 caaacaaaaa aaccccaccc cagttgacac tttaatattt cccaatgaag 1400

 actttattta tggaatggaa tggaaaaaaa aacagctatt ttgaaaatat 1450

 atttatatct acgaaaagaa gttgggaaaa caaatatttt aatcagagaa 1500

 ttattcctta aagatttaaa atgtatttag ttgtacattt tatatgggtt 1550

 caaccccagc acatgaagta taatggtcag atttattttg tatttattta 1600

 ctattataac cactttttag gaaaaaaata gctaatttgt atttatatgt 1650

 aatcaaaaga agtatcgggt ttgtacataa ttttccaaaa attgtagttg 1700

 ttttcagttg tgtgtattta agatgaaaag tctacatgga aggttactct 1750

 ggcaaagtgc ttagcacgtt tgcttttttg cagtgctact gttgagttca 1800

 caagttcaag tccagaaaaa aaaagtggat aatccactct gctgactttc 1850

 aagattatta tattattcaa ttctcaggaa tgttgcagag tgattgtcca 1900

 atccatgaga atttacatcc ttattaggtg gaatatttgg ataagaacca 1950

 gacattgctg atctattata gaaactctcc tcctgcccct taatttacag 2000

 aaagaataaa gcaggatcca tagaaataat taggaaaacg atgaacctgc 2050

 aggaaagtga atgatggttt gttgttcttc tttcctaaat tagtgatccc 2100

 ttcaaagggg ctgatctggc caaagtattc aataaaacgt aagatttctt 2150

 catt 2154

<210> 1328
<211> 396
<212> PRT
<213> Homo sapien

<400> 1328
 Met Val Ala Gly Thr Arg Cys Leu Leu Ala Leu Leu Leu Pro Gln
   1               5                  10                  15

 Val Leu Leu Gly Gly Ala Ala Gly Leu Val Pro Glu Leu Gly Arg
                  20                  25                  30

 Arg Lys Phe Ala Ala Ala Ser Ser Gly Arg Pro Ser Ser Gln Pro
                  35                  40                  45

 Ser Asp Glu Val Leu Ser Glu Phe Glu Leu Arg Leu Leu Ser Met
                  50                  55                  60

 Phe Gly Leu Lys Gln Arg Pro Thr Pro Ser Arg Asp Ala Val Val
                  65                  70                  75

 Pro Pro Tyr Met Leu Asp Leu Tyr Arg Arg His Ser Gly Gln Pro
                  80                  85                  90

 Gly Ser Pro Ala Pro Asp His Arg Leu Glu Arg Ala Ala Ser Arg
                  95                 100                 105

 Ala Asn Thr Val Arg Ser Phe His His Glu Glu Ser Leu Glu Glu
                 110                 115                 120

 Leu Pro Glu Thr Ser Gly Lys Thr Thr Arg Arg Phe Phe Phe Asn
                 125                 130                 135

 Leu Ser Ser Ile Pro Thr Glu Glu Phe Ile Thr Ser Ala Glu Leu
                 140                 145                 150

 Gln Val Phe Arg Glu Gln Met Gln Asp Ala Leu Gly Asn Asn Ser
                 155                 160                 165

 Ser Phe His His Arg Ile Asn Ile Tyr Glu Ile Ile Lys Pro Ala
                 170                 175                 180

 Thr Ala Asn Ser Lys Phe Pro Val Thr Ser Leu Leu Asp Thr Arg
                 185                 190                 195

 Leu Val Asn Gln Asn Ala Ser Arg Trp Glu Ser Phe Asp Val Thr
                 200                 205                 210

 Pro Ala Val Met Arg Trp Thr Ala Gln Gly His Ala Asn His Gly
                 215                 220                 225

 Phe Val Val Glu Val Ala His Leu Glu Glu Lys Gln Gly Val Ser
                 230                 235                 240

 Lys Arg His Val Arg Ile Ser Arg Ser Leu His Gln Asp Glu His
                 245                 250                 255

 Ser Trp Ser Gln Ile Arg Pro Leu Leu Val Thr Phe Gly His Asp
                 260                 265                 270

 Gly Lys Gly His Pro Leu His Lys Arg Glu Lys Arg Gln Ala Lys
                 275                 280                 285

 His Lys Gln Arg Lys Arg Leu Lys Ser Ser Cys Lys Arg His Pro
                 290                 295                 300

 Leu Tyr Val Asp Phe Ser Asp Val Gly Trp Asn Asp Trp Ile Val
                 305                 310                 315

 Ala Pro Pro Gly Tyr His Ala Phe Tyr Cys His Gly Glu Cys Pro
                 320                 325                 330

 Phe Pro Leu Ala Asp His Leu Asn Ser Thr Asn His Ala Ile Val
                 335                 340                 345

 Gln Thr Leu Val Asn Ser Val Asn Ser Lys Ile Pro Lys Ala Cys
                 350                 355                 360

 Cys Val Pro Thr Glu Leu Ser Ala Ile Ser Met Leu Tyr Leu Asp
                 365                 370                 375

 Glu Asn Glu Lys Val Val Leu Lys Asn Tyr Gln Asp Met Val Val
                 380                 385                 390

 Glu Gly Cys Gly Cys Arg
                 395

<210> 1329
<211> 1547
<212> DNA
<213> Homo sapien

<400> 1329
 ggggacttct tgaacttgca gggagaataa cttgcgcacc ccactttgcg 50

 ccggtgcctt tgccccagcg gagcctgctt cgccatctcc gagccccacc 100

 gcccctccac tcctcggcct tgcccgacac tgagacgctg ttcccagcgt 150

 gaaaagagag actgcgcggc cggcacccgg gagaaggagg aggcaaagaa 200

 aaggaacgga cattcggtcc ttgcgccagg tcctttgacc agagtttttc 250

 catgtggacg ctctttcaat ggacgtgtcc ccgcgtgctt cttagacgga 300

 ctgcggtctc ctaaaggtcg accatggtgg ccgggacccg ctgtcttcta 350

 gcgttgctgc ttccccaggt cctcctgggc ggcgcggctg gcctcgttcc 400

 ggagctgggc cgcaggaagt tcgcggcggc gtcgtcgggc cgcccctcat 450

 cccagccctc tgacgaggtc ctgagcgagt tcgagttgcg gctgctcagc 500

 atgttcggcc tgaaacagag acccaccccc agcagggacg ccgtggtgcc 550

 cccctacatg ctagacctgt atcgcaggca ctcaggtcag ccgggctcac 600

 ccgccccaga ccaccggttg gagagggcag ccagccgagc caacactgtg 650

 cgcagcttcc accatgaaga atctttggaa gaactaccag aaacgagtgg 700

 gaaaacaacc cggagattct tctttaattt aagttctatc cccacggagg 750

 agtttatcac ctcagcagag cttcaggttt tccgagaaca gatgcaagat 800

 gctttaggaa acaatagcag tttccatcac cgaattaata tttatgaaat 850

 cataaaacct gcaacagcca actcgaaatt ccccgtgacc agacttttgg 900

 acaccaggtt ggtgaatcag aatgcaagca ggtgggaaag ttttgatgtc 950

 acccccgctg tgatgcggtg gactgcacag ggacacgcca accatggatt 1000

 cgtggtggaa gtggcccact tggaggagaa acaaggtgtc tccaagagac 1050

 atgttaggat aagcaggtct ttgcaccaag atgaacacag ctggtcacag 1100

 ataaggccat tgctagtaac ttttggccat gatggaaaag ggcatcctct 1150

 ccacaaaaga gaaaaacgtc aagccaaaca caaacagcgg aaacgcctta 1200

 agtccagctg taagagacac cctttgtacg tggacttcag tgacgtgggg 1250

 tggaatgact ggattgtggc tcccccgggg tatcacgcct tttactgcca 1300

 cggagaatgc ccttttcctc tggctgatca tctgaactcc actaatcatg 1350

 ccattgttca gacgttggtc aactctgtta actctaagat tcctaaggca 1400

 tgctgtgtcc cgacagaact cagtgctatc tcgatgctgt accttgacga 1450

 gaatgaaaag gttgtattaa agaactatca ggacatggtt gtggagggtt 1500

 gtgggtgtcg ctagtacagc aaaattaaat acataaatat atatata 1547

<210> 1330
<211> 396
<212> PRT
<213> Homo sapien

<400> 1330
 Met Val Ala Gly Thr Arg Cys Leu Leu Ala Leu Leu Leu Pro Gln
   1               5                  10                  15

 Val Leu Leu Gly Gly Ala Ala Gly Leu Val Pro Glu Leu Gly Arg
                  20                  25                  30

 Arg Lys Phe Ala Ala Ala Ser Ser Gly Arg Pro Ser Ser Gln Pro
                  35                  40                  45

 Ser Asp Glu Val Leu Ser Glu Phe Glu Leu Arg Leu Leu Ser Met
                  50                  55                  60

 Phe Gly Leu Lys Gln Arg Pro Thr Pro Ser Arg Asp Ala Val Val
                  65                  70                  75

 Pro Pro Tyr Met Leu Asp Leu Tyr Arg Arg His Ser Gly Gln Pro
                  80                  85                  90

 Gly Ser Pro Ala Pro Asp His Arg Leu Glu Arg Ala Ala Ser Arg
                  95                 100                 105

 Ala Asn Thr Val Arg Ser Phe His His Glu Glu Ser Leu Glu Glu
                 110                 115                 120

 Leu Pro Glu Thr Ser Gly Lys Thr Thr Arg Arg Phe Phe Phe Asn
                 125                 130                 135

 Leu Ser Ser Ile Pro Thr Glu Glu Phe Ile Thr Ser Ala Glu Leu
                 140                 145                 150

 Gln Val Phe Arg Glu Gln Met Gln Asp Ala Leu Gly Asn Asn Ser
                 155                 160                 165

 Ser Phe His His Arg Ile Asn Ile Tyr Glu Ile Ile Lys Pro Ala
                 170                 175                 180

 Thr Ala Asn Ser Lys Phe Pro Val Thr Arg Leu Leu Asp Thr Arg
                 185                 190                 195

 Leu Val Asn Gln Asn Ala Ser Arg Trp Glu Ser Phe Asp Val Thr
                 200                 205                 210

 Pro Ala Val Met Arg Trp Thr Ala Gln Gly His Ala Asn His Gly
                 215                 220                 225

 Phe Val Val Glu Val Ala His Leu Glu Glu Lys Gln Gly Val Ser
                 230                 235                 240

 Lys Arg His Val Arg Ile Ser Arg Ser Leu His Gln Asp Glu His
                 245                 250                 255

 Ser Trp Ser Gln Ile Arg Pro Leu Leu Val Thr Phe Gly His Asp
                 260                 265                 270

 Gly Lys Gly His Pro Leu His Lys Arg Glu Lys Arg Gln Ala Lys
                 275                 280                 285

 His Lys Gln Arg Lys Arg Leu Lys Ser Ser Cys Lys Arg His Pro
                 290                 295                 300

 Leu Tyr Val Asp Phe Ser Asp Val Gly Trp Asn Asp Trp Ile Val
                 305                 310                 315

 Ala Pro Pro Gly Tyr His Ala Phe Tyr Cys His Gly Glu Cys Pro
                 320                 325                 330

 Phe Pro Leu Ala Asp His Leu Asn Ser Thr Asn His Ala Ile Val
                 335                 340                 345

 Gln Thr Leu Val Asn Ser Val Asn Ser Lys Ile Pro Lys Ala Cys
                 350                 355                 360

 Cys Val Pro Thr Glu Leu Ser Ala Ile Ser Met Leu Tyr Leu Asp
                 365                 370                 375

 Glu Asn Glu Lys Val Val Leu Lys Asn Tyr Gln Asp Met Val Val
                 380                 385                 390

 Glu Gly Cys Gly Cys Arg
                 395

<210> 1331
<211> 4045
<212> DNA
<213> Homo sapien

<400> 1331
 gcagccagag ctcagcaggg ccctggagag atggccacgg tcccagcacc 50

 ggggaggact ggagagcgcg cgctgccacc gccccatgtc tcagccaggg 100

 cttccttcct cggctccacc ctgtggatgt aatggcggcc cctgctctgt 150

 cctggcgtct gcccctcctc atcctcctcc tgcccctggc tacctcttgg 200

 gcatctgcag cggtgaatgg cacttcccag ttcacatgct tctacaactc 250

 gagagccaac atctcctgtg tctggagcca agatggggct ctgcaggaca 300

 cttcctgcca agtccatgcc tggccggaca gacggcggtg gaaccaaacc 350

 tgtgagctgc tccccgtgag tcaagcatcc tgggcctgca acctgatcct 400

 cggagcccca gattctcaga aactgaccac agttgacatc gtcaccctga 450

 gggtgctgtg ccgtgagggg gtgcgatgga gggtgatggc catccaggac 500

 ttcaagccct ttgagaacct tcgcctgatg gcccccatct ccctccaagt 550

 tgtccacgtg gagacccaca gatgcaacat aagctgggaa atctcccaag 600

 cctcccacta ctttgaaaga cacctggagt tcgaggcccg gacgctgtcc 650

 ccaggccaca cctgggagga ggcccccctg ctgactctca agcagaagca 700

 ggaatggatc tgcctggaga cgctcacccc agacacccag tatgagtttc 750

 aggtgcgggt caagcctctg caaggcgagt tcacgacctg gagcccctgg 800

 agccagcccc tggccttcag gacaaagcct gcagcccttg ggaaggacac 850

 cattccgtgg ctcggccacc tcctcgtggg cctcagcggg gcttttggct 900

 tcatcatctt agtgtacttg ctgatcaact gcaggaacac cgggccatgg 950

 ctgaagaagg tcctgaagtg taacacccca gacccctcga agttcttttc 1000

 ccagctgagc tcagagcatg gaggagacgt ccagaagtgg ctctcttcgc 1050

 ccttcccctc atcgtccttc agccctggcg gcctggcacc tgagatctcg 1100

 ccactagaag tgctggagag ggacaaggtg acgcagctgc tcctgcagca 1150

 ggacaaggtg cctgagcccg catccttaag cagcaaccac tcgctgacca 1200

 gctgcttcac caaccagggt tacttcttct tccacctccc ggatgccttg 1250

 gagatagagg cctgccaggt gtactttact tacgacccct actcagagga 1300

 agaccctgat gagggtgtgg ccggggcacc cacagggtct tccccccaac 1350

 ccctgcagcc tctgtcaggg gaggacgacg cctactgcac cttcccctcc 1400

 agggatgacc tgctgctctt ctcccccagt ctcctcggtg gccccagccc 1450

 cccaagcact gcccctgggg gcagtggggc cggtgaagag aggatgcccc 1500

 cttctttgca agaaagagtc cccagagact gggaccccca gcccctgggg 1550

 cctcccaccc caggagtccc agacctggtg gattttcagc caccccctga 1600

 gctggtgctg cgagaggctg gggaggaggt ccctgacgct ggccccaggg 1650

 agggagtcag tttcccctgg tccaggcctc ctgggcaggg ggagttcagg 1700

 gcccttaatg ctcgcctgcc cctgaacact gatgcctact tgtccctcca 1750

 agaactccag ggtcaggacc caactcactt ggtgtagaca gatggccagg 1800

 gtgggaggca ggcagctgcc tgctctgcgc cgagcctcag aaggaccctg 1850

 ttgagggtcc tcagtccact gctgaggaca ctcagtgtcc agttgcagct 1900

 ggacttctcc acccggatgg cccccaccca gtcctgcaca cttggtccat 1950

 ccatttccaa acctccactg ctgctcccgg gtcctgctgc ccgagccagg 2000

 aactgtgtgt gttgcagggg ggcagtaact ccccaactcc ctcgttaatc 2050

 acaggatccc acgaatttag gctcagaagc atcgctcctc tccagccctg 2100

 cagctattca ccaatatcag tcctcgcggc tctccagggc tccctgccct 2150

 gacctcttcc ctgggttttc tgccccagcc tcctccttcc ctcccctccc 2200

 cgtccacagg gcagcctgag cgtgctttcc aaaacccaaa tatggccacg 2250

 ctccccctcg gttcaaaacc ttgcacaggt cccactgccc tcagccccac 2300

 ttctcagcct ggtacttgta cctccggtgt cgtgtgggga catccccttc 2350

 tgcaatcctc cctaccgtcc tcctgagcca ctcagagctc cctcacaccc 2400

 cctctgttgc acatgctatt ccctggggct gctgtgcgct ccccctcatc 2450

 taggtgacaa acttccctga ctcttcaagt gccggttttg cttctcctgg 2500

 agggaagcac tgcctccctt aatctgccag aaacttctag cgtcagtgct 2550

 ggagggagaa gctgtcaggg acccagggcg cctggagaaa gaggccctgt 2600

 tactattcct ttgggatctc tgaggcctca gagtgcttgg ctgctgtatc 2650

 tttaatgctg gggcccaagt aagggcacag atccccccac aaagtggatg 2700

 cctgctgcat cttcccacag tggcttcaca gacccacaag agaagctgat 2750

 ggggagtaaa ccctggagtc cgaggcccag gcagcagccc cgcctagtgg 2800

 tgggccctga tgctgccagg cctgggacct cccactgccc cctccactgg 2850

 aggggtctcc tctgcagctc agggactggc acactggcct ccagaagggc 2900

 agctccacag ggcagggcct cattattttt cactgcccca gacacagtgc 2950

 ccaacacccc gtcgtatacc ctggatgaac gaattaatta cctggcacca 3000

 cctcgtctgg gctccctgcg cctgacattc acacagagag gcagagtccc 3050

 gtgcccatta ggtctggcat gccccctcct gcaaggggct caacccccta 3100

 ccccgacccc tccacgtatc tttcctaggc agatcacgtt gcaatggctc 3150

 aaacaacatt ccaccccagc aggacagtga ccccagtccc agctaactct 3200

 gacctgggag ccctcaggca cctgcactta caggccttgc tcacagctga 3250

 ttgggcacct gaccacacgc ccccacaggc tctgaccagc agcctatgag 3300

 ggggtttggc accaagctct gtccaatcag gtaggctggg cctgaactag 3350

 ccaatcagat caactctgtc ttgggcgttt gaactcaggg agggaggccc 3400

 ttgggagcag gtgcttgtgg acaaggctcc acaagcgttg agccttggaa 3450

 aggtagacaa gcgttgagcc actaagcaga ggaccttggg ttcccaatac 3500

 aaaaatacct actgctgaga gggctgctga ccatttggtc aggattcctg 3550

 ttgcctttat atccaaaata aactcccctt tcttgaggtt gtctgagtct 3600

 tgggtctatg ccttgaaaaa agctgaatta ttggacagtc tcacctcctg 3650

 ccatagggtc ctgaatgttt cagaccacaa ggggctccac acctttgctg 3700

 tgtgttctgg ggcaacctac taatcctctc tgcaagtcgg tctccttatc 3750

 cccccaaatg gaaattgtat ttgccttctc cactttggga ggctcccact 3800

 tcttgggagg gttacatttt ttaagtctta atcatttgtg acatatgtat 3850

 ctatacatcc gtatctttta atgatccgtg tgtaccatct ttgtgattat 3900

 ttccttaata ttttttcttt aagtcagttc attttcgttg aaatacattt 3950

 atttaaagaa aaatctttgt tactctgtaa atgaaaaaac ccattttcgc 4000

 tataaataaa aggtaactgt acaaaataag tacaatgcaa caaaa 4045

<210> 1332
<211> 551
<212> PRT
<213> Homo sapien

<400> 1332
 Met Ala Ala Pro Ala Leu Ser Trp Arg Leu Pro Leu Leu Ile Leu
   1               5                  10                  15

 Leu Leu Pro Leu Ala Thr Ser Trp Ala Ser Ala Ala Val Asn Gly
                  20                  25                  30

 Thr Ser Gln Phe Thr Cys Phe Tyr Asn Ser Arg Ala Asn Ile Ser
                  35                  40                  45

 Cys Val Trp Ser Gln Asp Gly Ala Leu Gln Asp Thr Ser Cys Gln
                  50                  55                  60

 Val His Ala Trp Pro Asp Arg Arg Arg Trp Asn Gln Thr Cys Glu
                  65                  70                  75

 Leu Leu Pro Val Ser Gln Ala Ser Trp Ala Cys Asn Leu Ile Leu
                  80                  85                  90

 Gly Ala Pro Asp Ser Gln Lys Leu Thr Thr Val Asp Ile Val Thr
                  95                 100                 105

 Leu Arg Val Leu Cys Arg Glu Gly Val Arg Trp Arg Val Met Ala
                 110                 115                 120

 Ile Gln Asp Phe Lys Pro Phe Glu Asn Leu Arg Leu Met Ala Pro
                 125                 130                 135

 Ile Ser Leu Gln Val Val His Val Glu Thr His Arg Cys Asn Ile
                 140                 145                 150

 Ser Trp Glu Ile Ser Gln Ala Ser His Tyr Phe Glu Arg His Leu
                 155                 160                 165

 Glu Phe Glu Ala Arg Thr Leu Ser Pro Gly His Thr Trp Glu Glu
                 170                 175                 180

 Ala Pro Leu Leu Thr Leu Lys Gln Lys Gln Glu Trp Ile Cys Leu
                 185                 190                 195

 Glu Thr Leu Thr Pro Asp Thr Gln Tyr Glu Phe Gln Val Arg Val
                 200                 205                 210

 Lys Pro Leu Gln Gly Glu Phe Thr Thr Trp Ser Pro Trp Ser Gln
                 215                 220                 225

 Pro Leu Ala Phe Arg Thr Lys Pro Ala Ala Leu Gly Lys Asp Thr
                 230                 235                 240

 Ile Pro Trp Leu Gly His Leu Leu Val Gly Leu Ser Gly Ala Phe
                 245                 250                 255

 Gly Phe Ile Ile Leu Val Tyr Leu Leu Ile Asn Cys Arg Asn Thr
                 260                 265                 270

 Gly Pro Trp Leu Lys Lys Val Leu Lys Cys Asn Thr Pro Asp Pro
                 275                 280                 285

 Ser Lys Phe Phe Ser Gln Leu Ser Ser Glu His Gly Gly Asp Val
                 290                 295                 300

 Gln Lys Trp Leu Ser Ser Pro Phe Pro Ser Ser Ser Phe Ser Pro
                 305                 310                 315

 Gly Gly Leu Ala Pro Glu Ile Ser Pro Leu Glu Val Leu Glu Arg
                 320                 325                 330

 Asp Lys Val Thr Gln Leu Leu Leu Gln Gln Asp Lys Val Pro Glu
                 335                 340                 345

 Pro Ala Ser Leu Ser Ser Asn His Ser Leu Thr Ser Cys Phe Thr
                 350                 355                 360

 Asn Gln Gly Tyr Phe Phe Phe His Leu Pro Asp Ala Leu Glu Ile
                 365                 370                 375

 Glu Ala Cys Gln Val Tyr Phe Thr Tyr Asp Pro Tyr Ser Glu Glu
                 380                 385                 390

 Asp Pro Asp Glu Gly Val Ala Gly Ala Pro Thr Gly Ser Ser Pro
                 395                 400                 405

 Gln Pro Leu Gln Pro Leu Ser Gly Glu Asp Asp Ala Tyr Cys Thr
                 410                 415                 420

 Phe Pro Ser Arg Asp Asp Leu Leu Leu Phe Ser Pro Ser Leu Leu
                 425                 430                 435

 Gly Gly Pro Ser Pro Pro Ser Thr Ala Pro Gly Gly Ser Gly Ala
                 440                 445                 450

 Gly Glu Glu Arg Met Pro Pro Ser Leu Gln Glu Arg Val Pro Arg
                 455                 460                 465

 Asp Trp Asp Pro Gln Pro Leu Gly Pro Pro Thr Pro Gly Val Pro
                 470                 475                 480

 Asp Leu Val Asp Phe Gln Pro Pro Pro Glu Leu Val Leu Arg Glu
                 485                 490                 495

 Ala Gly Glu Glu Val Pro Asp Ala Gly Pro Arg Glu Gly Val Ser
                 500                 505                 510

 Phe Pro Trp Ser Arg Pro Pro Gly Gln Gly Glu Phe Arg Ala Leu
                 515                 520                 525

 Asn Ala Arg Leu Pro Leu Asn Thr Asp Ala Tyr Leu Ser Leu Gln
                 530                 535                 540

 Glu Leu Gln Gly Gln Asp Pro Thr His Leu Val
                 545                 550

<210> 1333
<211> 2646
<212> DNA
<213> Homo sapien

<400> 1333
 tttccttcct cttttggcaa catggcgggc ggagaagctg gagtgactct 50

 agggcagccg catctttcgc gtcaggatct caccaccttg gatgttacca 100

 agttgacgcc actttcacac gaagttatca gcagacaagc cacaattaac 150

 ataggtacaa ttggtcatgt agctcatggg aaatccacag tcgtcaaagc 200

 tatttctgga gttcatactg tcaggttcaa aaatgaacta gaaagaaata 250

 ttacaatcaa gcttggatat gctaatgcta agatttataa gcttgatgac 300

 ccaagttgcc ctcggccaga atgttataga tcttgtggga gcagtacacc 350

 tgacgagttt cctacggaca ttccagggac caaagggaac ttcaaattag 400

 tcagacatgt ttcctttgtt gactgtcctg gccacgatat tttgatggct 450

 actatgctga acggtgcagc agtgatggat gcagctcttc tgttgatagc 500

 tggtaatgaa tcttgccctc agcctcagac atcggaacac ctggctgcta 550

 tagagatcat gaaactgaag catattttga ttctacaaaa taaaattgat 600

 ttggtaaaag aaagtcaggc taaagaacaa tacgagcaga tccttgcatt 650

 tgtccaaggt acagtagcag agggagctcc cattattcca atttcagctc 700

 agctgaaata caatattgaa gttgtttgtg agtacatagt aaagaaaatt 750

 ccagtacccc caagagactt tacttcagag ccccggctta ttgttattag 800

 atcttttgat gtcaacaaac ctggctgtga agttgatgac cttaagggag 850

 gtgtagctgg tggtagtatc ctaaaaggag tattaaaggt gggccaggag 900

 atagaagtaa gacctggtat tgtttccaaa gatagtgaag gaaaactcat 950

 gtgtaaacca atcttttcca aaattgtatc actttttgcg gagcataatg 1000

 atctgcaata tgctgctcca ggcggtctta ttggagttgg aacaaaaatt 1050

 gaccccactt tgtgccgggc tgacagaatg gtggggcaag tacttggtgc 1100

 agtcggagct ttacctgaga tattcacaga attggaaatt tcctatttcc 1150

 tgcttagacg gcttctaggt gtacgcactg aaggagacaa gaaagcagca 1200

 aaggttcaaa agctgtctaa gaatgaagtg ctcatggtga acataggatc 1250

 cctgtcaaca ggagggagag ttagtgctgt caaggccgat ttgggtaaaa 1300

 ttgttttgac caatccagtg tgcacagagg taggagaaaa aattgccctt 1350

 agccgaagag ttgaaaaaca ctggcgttta attggttggg gtcagataag 1400

 aagaggagtg acaatcaagc caacagtaga tgatgactga agaataccag 1450

 ttaaataata cattcggatg gatttggaag ttggaattcc tcttaacaac 1500

 caaggggttt attttcaaag caatattggg gaattgattt cacagttcgt 1550

 taccttagta ggtaacggta aggttattct cttttttttt ttttttggtt 1600

 atgaaaactt agggactaaa attaatataa aaattggcat aatgttggat 1650

 tgaatctaca ttttggcaga agttaaacat tcccacataa tgtcaaaatt 1700

 atacatcatg cagttctgtt tttttgtttg tttaattttg ttttgttttt 1750

 gagtctggct ctgtcaccca ggctggagtg cagtggcgtg atctgcaacc 1800

 tctgcccccc gggttcaagc gattctcctg cctcagcctc ccgagtagct 1850

 gagattacag gtgcgcgcca ccacacttgg ctaatttttg tattattagt 1900

 agagacgggg tttcagcatg ttggctaggc cggtctctcc tgacctcagg 1950

 gtgatcagcc cacctcggcc tcacaaagtg ctgggattac aggcgtgagc 2000

 caccttgccc agcccacatc atacagtttg aaatgaaact ttgccacaac 2050

 cagcctttgc tgtagcacac acatatatca ctgaacctgt ttgaaataaa 2100

 gttttttttc tttttcatga ttcgtctttg agtacctcca ggctgaaaga 2150

 ctgttgtacc agtaaaaact taaaggcaca aattctcctt gaagaccttc 2200

 tcccttttat gtggccccat attttatgtt gctttatctt tgaaattttg 2250

 catgaaaagg aaatgaatgg attcgaatga aattgtcctt tagagcatga 2300

 ttacttgttc ccatggacaa atatttttct ccccttgctc ttcctggcct 2350

 gaaacacggg aaaccagagt caaaagttat ctccctctcc ctgtgatgcc 2400

 ttgagatttt tttctgcgtt gtttaatgcc tgaaatccaa gtcttcctcc 2450

 atgggaaaat actgttatac caaataattc tagatgagta acaaagatct 2500

 ttttaggcct tcattttatg ttttttctta actgttatat tatgattgtg 2550

 acatagatta tactactact aatttttgga tgtttcaaaa ggtcaagaag 2600

 taaaagatgt tagaaagcaa aaaaaaaaaa aaaaaaaaaa aaaaaa 2646

<210> 1334
<211> 472
<212> PRT
<213> Homo sapien

<400> 1334
 Met Ala Gly Gly Glu Ala Gly Val Thr Leu Gly Gln Pro His Leu
   1               5                  10                  15

 Ser Arg Gln Asp Leu Thr Thr Leu Asp Val Thr Lys Leu Thr Pro
                  20                  25                  30

 Leu Ser His Glu Val Ile Ser Arg Gln Ala Thr Ile Asn Ile Gly
                  35                  40                  45

 Thr Ile Gly His Val Ala His Gly Lys Ser Thr Val Val Lys Ala
                  50                  55                  60

 Ile Ser Gly Val His Thr Val Arg Phe Lys Asn Glu Leu Glu Arg
                  65                  70                  75

 Asn Ile Thr Ile Lys Leu Gly Tyr Ala Asn Ala Lys Ile Tyr Lys
                  80                  85                  90

 Leu Asp Asp Pro Ser Cys Pro Arg Pro Glu Cys Tyr Arg Ser Cys
                  95                 100                 105

 Gly Ser Ser Thr Pro Asp Glu Phe Pro Thr Asp Ile Pro Gly Thr
                 110                 115                 120

 Lys Gly Asn Phe Lys Leu Val Arg His Val Ser Phe Val Asp Cys
                 125                 130                 135

 Pro Gly His Asp Ile Leu Met Ala Thr Met Leu Asn Gly Ala Ala
                 140                 145                 150

 Val Met Asp Ala Ala Leu Leu Leu Ile Ala Gly Asn Glu Ser Cys
                 155                 160                 165

 Pro Gln Pro Gln Thr Ser Glu His Leu Ala Ala Ile Glu Ile Met
                 170                 175                 180

 Lys Leu Lys His Ile Leu Ile Leu Gln Asn Lys Ile Asp Leu Val
                 185                 190                 195

 Lys Glu Ser Gln Ala Lys Glu Gln Tyr Glu Gln Ile Leu Ala Phe
                 200                 205                 210

 Val Gln Gly Thr Val Ala Glu Gly Ala Pro Ile Ile Pro Ile Ser
                 215                 220                 225

 Ala Gln Leu Lys Tyr Asn Ile Glu Val Val Cys Glu Tyr Ile Val
                 230                 235                 240

 Lys Lys Ile Pro Val Pro Pro Arg Asp Phe Thr Ser Glu Pro Arg
                 245                 250                 255

 Leu Ile Val Ile Arg Ser Phe Asp Val Asn Lys Pro Gly Cys Glu
                 260                 265                 270

 Val Asp Asp Leu Lys Gly Gly Val Ala Gly Gly Ser Ile Leu Lys
                 275                 280                 285

 Gly Val Leu Lys Val Gly Gln Glu Ile Glu Val Arg Pro Gly Ile
                 290                 295                 300

 Val Ser Lys Asp Ser Glu Gly Lys Leu Met Cys Lys Pro Ile Phe
                 305                 310                 315

 Ser Lys Ile Val Ser Leu Phe Ala Glu His Asn Asp Leu Gln Tyr
                 320                 325                 330

 Ala Ala Pro Gly Gly Leu Ile Gly Val Gly Thr Lys Ile Asp Pro
                 335                 340                 345

 Thr Leu Cys Arg Ala Asp Arg Met Val Gly Gln Val Leu Gly Ala
                 350                 355                 360

 Val Gly Ala Leu Pro Glu Ile Phe Thr Glu Leu Glu Ile Ser Tyr
                 365                 370                 375

 Phe Leu Leu Arg Arg Leu Leu Gly Val Arg Thr Glu Gly Asp Lys
                 380                 385                 390

 Lys Ala Ala Lys Val Gln Lys Leu Ser Lys Asn Glu Val Leu Met
                 395                 400                 405

 Val Asn Ile Gly Ser Leu Ser Thr Gly Gly Arg Val Ser Ala Val
                 410                 415                 420

 Lys Ala Asp Leu Gly Lys Ile Val Leu Thr Asn Pro Val Cys Thr
                 425                 430                 435

 Glu Val Gly Glu Lys Ile Ala Leu Ser Arg Arg Val Glu Lys His
                 440                 445                 450

 Trp Arg Leu Ile Gly Trp Gly Gln Ile Arg Arg Gly Val Thr Ile
                 455                 460                 465

 Lys Pro Thr Val Asp Asp Asp
                 470

<210> 1335
<211> 5597
<212> DNA
<213> Homo sapien

<400> 1335
 cgcgcttccg ggttggctgt ggctgtggct gcggcggcgg cgcaggagca 50

 gaaaccggtg cggcgcagaa gccccagagg cgggcggggc ggagcggagg 100

 gccagcgggc cccggcgtgg gtctcccgcc aggccgccgg atttaaccct 150

 tagtggcttc tgaagaaaat ggcagaaaca tcgccagagc cttctgggca 200

 gcttgttgta cactcagacg ctcacagtga cactgtgctg gccagttttg 250

 aggatcagag gaagaaaggc ttcctctgtg acattacttt aatcgtggag 300

 aatgtacatt tccgggccca caaagcctta cttgctgcca gtagtgaata 350

 cttctcaatg atgtttgcag aagaggggga aatcggccaa tccatttata 400

 tgctggaagg catggttgca gacacctttg gtatcctgct ggaatttatc 450

 tacacaggtt atctccatgc cagtgagaaa agtacagaac aaatcctggc 500

 tactgctcag ttcttaaaag tctatgacct ggtaaaggct tacacagact 550

 tccaaaataa tcatagctcc ccaaagccaa caactttgaa cactgctggt 600

 gccccagtgg ttgttatccc taataagaaa aacgatcctc caaagcggaa 650

 acggggaaga ccaaaaaaag tcaatacatt gcaggaggag aaatcagaac 700

 tggctgcaga ggaagaaata cagttaagag tgaacaattc agttcagaat 750

 agacaaaact ttgtggttaa aggagacagt ggtgtactga atgagcaaat 800

 tgcagcaaaa gaaaaggaag aatcggagcc tacttgtgag ccaagtagag 850

 aggaggaaat gccagttgaa aaagatgaga actatgatcc caagaccgag 900

 gatggccagg caagccagag tcgatacagc aagcggagga tttggagatc 950

 cgtcaaactt aaagattaca aacttgttgg ggatcaagag gaccatggtt 1000

 cagccaagag gatctgtgga aggagaaagc gccctggagg ccctgaggcc 1050

 cgctgtaaag actgtggcaa ggtctttaag tacaatcact ttttagcaat 1100

 ccaccagagg agccacacag gggagcgacc tttcaaatgt aatgagtgtg 1150

 gaaaaggctt tgcccagaag cactcgctac aggtccacac caggatgcac 1200

 acaggcgagc ggccgtacac ctgcaccgtg tgcagcaagg ctctgaccac 1250

 caagcactca ctgctggagc acatgagcct gcactcagga cagaagtctt 1300

 ttacctgtga tcaatgcgga aaatatttca gccagaacag acagctaaag 1350

 agccattacc gagttcatac aggccactca ttaccggaat gcaaagactg 1400

 ccatcgcaaa ttcatggatg tgtctcagct aaagaaacat ctgcgaacac 1450

 acacaggtga gaagccattt acttgtgaaa tctgtggcaa atctttcaca 1500

 gcaaagagtt ctcttcagac ccacatcaga atccatcgag gagaaaagcc 1550

 atactcctgt ggcatttgtg gcaaatcctt ctctgactcc agtgccaaaa 1600

 ggagacactg cattctacac actggcaaga agcctttctc ctgccctgag 1650

 tgtaacttac agtttgctcg cttagacaac ttgaaggctc acttgaaaat 1700

 tcatagcaag gagaagcatg cttcagatgc cagcagcatt tctggcagta 1750

 gtaatacaga agaggtcagg aatattcttc agctacagcc atatcaactc 1800

 tctacctcgg gagagcagga aattcagctt ctcgtaaccg attctgtaca 1850

 taacatcaat ttcatgcccg gtcctagcca gggaatcagc attgtgactg 1900

 cagagagttc ccaaaacatg actgcagacc aggctgctaa tcttaccctg 1950

 ctcacgcagc agccagagca actgcagaat ttaattcttt cagctcaaca 2000

 ggagcaaaca gaacacattc agagcctcaa tatgattgaa agccagatgg 2050

 ggccctcaca aacagagcca gtgcacgtga tcactctgtc caaggaaaca 2100

 ctggaacatc ttcatgccca tcaagagcaa acagaggagc tccatttagc 2150

 tacaagtact tcagatccag ctcagcacct gcagctgaca caggagcctg 2200

 gtccgccacc acccactcac cacgtgcccc agccaacgcc acttggccag 2250

 gagcagagct gacctgtaaa cacgtttgac tgcttgattg ggctcttctt 2300

 ataagccagc tctgactgga ttttgaacgc ttgaaatcag gctctccaca 2350

 ccattgactt gcagatgctt ctgtgagagc tgtgatggct aactgatgtt 2400

 tataatgccc tccatccagg tagcaagatg tgtgtatgtc ttgtctaagg 2450

 tactgatttg tattgagcat ttcaatatta ttgaatggtt ttcattttaa 2500

 tctgcaatgt ctcataaaga ctcgggtagt ttttctttgg gggcattgat 2550

 ctcagttttt ctgtaaggtt taaatgttca cagccatagg ttatggtctt 2600

 gccaacctcc ccagttatgt ttttttgttt tctaggacaa agggagtcat 2650

 tttggttgaa ctgggcagaa tggtttgttc tattttctta tttttcttag 2700

 gcaacacagt tgttaccaca agacaagtca gggctaaata tgacagatca 2750

 caatgtatgg ggaatttgcc cttttaataa tttccagtcc cctaagacaa 2800

 agtaaccctc aacgttttat ctttatgcag tacagtgggc ttattgtgtt 2850

 aacacttcag aaagattcaa actcataaac tcagtatttt aactcaaaat 2900

 tcatgtaaca agatagccaa aagcatagga tttcttaaaa ttctgaattc 2950

 gtcttttctg agaaacataa atttacatat ttttcaacag aaggctatca 3000

 aaattttaat taagtttaaa atacaaaatt ggatcaagac attcacccta 3050

 aattctgaat ttttgtcaga aaagagattt gattttcatg aaggtaaagc 3100

 tttcttcact attctggaac ataaaacttt attcagtgta atttaagtct 3150

 tatatatact ctactgaatt ctaactgatc tcctgaaaat gttgatctac 3200

 gtgttgtgtc tgataacttt ctggagatgg aagcttataa ttcattttta 3250

 ttgcagacta gttaaatccc acaaagtgaa tatcttctcc taatctttcc 3300

 ttttttagag acggggtctc actgtatcac ccaggccaga gtgtagtggc 3350

 acaatcattg ctcactgtag cctcgaattc ctgggctcaa gcaaccctcc 3400

 caccttagcc tccctagtag ctgggactac agggatgtac caccacaccc 3450

 agctaatctt catctaatct taaaactttg agcctcagag actttgtagc 3500

 cagcatgtgt ctgtaattgt atgattttta aatcatcatc aaaagattaa 3550

 attatgtttg ggttaggttt tcaagctaag cttattgaat tcttttacca 3600

 ctttcatgta agctggtagg ggatttttga gaaaagaagg tgggcactag 3650

 tatatctaaa ttaacaatgc tgatggggag tagggggtaa tctactctaa 3700

 aattaataga gcctttccat caattgtttt gttttagaca tccttgattt 3750

 ctccctaaat caaataagtt atttggaggt tagagtaata gagaattctt 3800

 caggtttgag agaagataaa aacattttgg ttgcatattt gctaagctat 3850

 attttattat atgtaattca caaaacttcc aaaatgatat atatcttata 3900

 tgtatcaacc aaactaatgt taaatcaggc ctgactagag caaagataac 3950

 aattttttac aaacactgtt aagccctaag tattatttca ggttctcgtt 4000

 taaactgttt aattttattc ttaaaacaca aagtttttac caacttttca 4050

 aagcccacca atccacattt tctccaggaa attaaatatt taagtaagtg 4100

 agtgtttact cactctggat agctaggtga ttattcagaa aatacggtta 4150

 catagctatt tataagtcaa gtttcactgg ctctataaca gtctacctct 4200

 acactaagag aactataaca tgaacaacat aggtcacttt aaatgttcta 4250

 gtagcaactt ttaaaaacat aaaaagaagc aggtgaaaat gttaataaaa 4300

 gtttatttaa tccaacattt gccaaatatt tcaacatata aaaatatatt 4350

 agtgagacat tttacattct ctttttcata ctaagctttc gaaatctggt 4400

 gtgtatttta cactttctgc acatctccat ttggatgcta atgttcattg 4450

 gacatacttg atctgtattt agatttcata caacttacag ttgaaaacag 4500

 attctcatat caagtagcta agacaaaagt ttttttcaag aattgaaata 4550

 agtatcagtt taaaaattta tattaaattt attaaaatta aaatccagtt 4600

 ccttgttgca tgggacacag tgcaaatgct tgataagcac atgtggctag 4650

 tggctgctat attggacagc atgggccacc tgtttctaac ttgagcatca 4700

 gtcctagcta tgcctgaatt atttgaccag ctgtcaaaga gaaacaagga 4750

 aatgatagct ttgttaatct agcctctttc tttgtcccac atatacattc 4800

 tacccctttg aataaaaaag ttcaatgacg ccgggcgtgg aggctcatgc 4850

 ctgtaatccc agcactttgg gaggccaagg tgggcggatc acgaggtcag 4900

 gagttcgagg gcagcctgac caacatagtg aaaccccatc tctactaaaa 4950

 atacaaaaat tagctgggcg tggtggtgta cccctgtaat cccagctact 5000

 cgggaggctg agacaggaga atcacttgag cccaggaggc ggaggctgca 5050

 gtgagctgag atcacgccat tgcactcaag cctggcgaca gagcgagact 5100

 ccgtctcaaa aaaaaaagtt aaatgacttg agtacccaaa agaaatgtcg 5150

 tgaacatgaa agtacttctc atgtgtcctt gagaaatgat gttgctagtg 5200

 cagtgtttca caattcattt tctactaaat gtgtaccatt ttttaaattg 5250

 ttttaacaga aatatagagt gtgtttctta ggaaatagaa tgttatgctt 5300

 tggggctcct gaaacacctc gttttgaagg tgaatctttg gttttctccc 5350

 agaagagggt ctgccttgag atgattggag ctcttaccat caaaatcagt 5400

 tattcaagtg cttgcccagt gcttcttgaa actcacctct actctgtatt 5450

 ttctacagtt ggttcttgtg ttataaatgt tgtgagcaac agattaaatg 5500

 atgctgagga atgaaaaaag attctcatta taaatgctta cctaggattc 5550

 tcattataga tgcttatcta ggttttcata aatgggaatg taacaat 5597

<210> 1336
<211> 697
<212> PRT
<213> Homo sapien

<400> 1336
 Met Ala Glu Thr Ser Pro Glu Pro Ser Gly Gln Leu Val Val His
   1               5                  10                  15

 Ser Asp Ala His Ser Asp Thr Val Leu Ala Ser Phe Glu Asp Gln
                  20                  25                  30

 Arg Lys Lys Gly Phe Leu Cys Asp Ile Thr Leu Ile Val Glu Asn
                  35                  40                  45

 Val His Phe Arg Ala His Lys Ala Leu Leu Ala Ala Ser Ser Glu
                  50                  55                  60

 Tyr Phe Ser Met Met Phe Ala Glu Glu Gly Glu Ile Gly Gln Ser
                  65                  70                  75

 Ile Tyr Met Leu Glu Gly Met Val Ala Asp Thr Phe Gly Ile Leu
                  80                  85                  90

 Leu Glu Phe Ile Tyr Thr Gly Tyr Leu His Ala Ser Glu Lys Ser
                  95                 100                 105

 Thr Glu Gln Ile Leu Ala Thr Ala Gln Phe Leu Lys Val Tyr Asp
                 110                 115                 120

 Leu Val Lys Ala Tyr Thr Asp Phe Gln Asn Asn His Ser Ser Pro
                 125                 130                 135

 Lys Pro Thr Thr Leu Asn Thr Ala Gly Ala Pro Val Val Val Ile
                 140                 145                 150

 Pro Asn Lys Lys Asn Asp Pro Pro Lys Arg Lys Arg Gly Arg Pro
                 155                 160                 165

 Lys Lys Val Asn Thr Leu Gln Glu Glu Lys Ser Glu Leu Ala Ala
                 170                 175                 180

 Glu Glu Glu Ile Gln Leu Arg Val Asn Asn Ser Val Gln Asn Arg
                 185                 190                 195

 Gln Asn Phe Val Val Lys Gly Asp Ser Gly Val Leu Asn Glu Gln
                 200                 205                 210

 Ile Ala Ala Lys Glu Lys Glu Glu Ser Glu Pro Thr Cys Glu Pro
                 215                 220                 225

 Ser Arg Glu Glu Glu Met Pro Val Glu Lys Asp Glu Asn Tyr Asp
                 230                 235                 240

 Pro Lys Thr Glu Asp Gly Gln Ala Ser Gln Ser Arg Tyr Ser Lys
                 245                 250                 255

 Arg Arg Ile Trp Arg Ser Val Lys Leu Lys Asp Tyr Lys Leu Val
                 260                 265                 270

 Gly Asp Gln Glu Asp His Gly Ser Ala Lys Arg Ile Cys Gly Arg
                 275                 280                 285

 Arg Lys Arg Pro Gly Gly Pro Glu Ala Arg Cys Lys Asp Cys Gly
                 290                 295                 300

 Lys Val Phe Lys Tyr Asn His Phe Leu Ala Ile His Gln Arg Ser
                 305                 310                 315

 His Thr Gly Glu Arg Pro Phe Lys Cys Asn Glu Cys Gly Lys Gly
                 320                 325                 330

 Phe Ala Gln Lys His Ser Leu Gln Val His Thr Arg Met His Thr
                 335                 340                 345

 Gly Glu Arg Pro Tyr Thr Cys Thr Val Cys Ser Lys Ala Leu Thr
                 350                 355                 360

 Thr Lys His Ser Leu Leu Glu His Met Ser Leu His Ser Gly Gln
                 365                 370                 375

 Lys Ser Phe Thr Cys Asp Gln Cys Gly Lys Tyr Phe Ser Gln Asn
                 380                 385                 390

 Arg Gln Leu Lys Ser His Tyr Arg Val His Thr Gly His Ser Leu
                 395                 400                 405

 Pro Glu Cys Lys Asp Cys His Arg Lys Phe Met Asp Val Ser Gln
                 410                 415                 420

 Leu Lys Lys His Leu Arg Thr His Thr Gly Glu Lys Pro Phe Thr
                 425                 430                 435

 Cys Glu Ile Cys Gly Lys Ser Phe Thr Ala Lys Ser Ser Leu Gln
                 440                 445                 450

 Thr His Ile Arg Ile His Arg Gly Glu Lys Pro Tyr Ser Cys Gly
                 455                 460                 465

 Ile Cys Gly Lys Ser Phe Ser Asp Ser Ser Ala Lys Arg Arg His
                 470                 475                 480

 Cys Ile Leu His Thr Gly Lys Lys Pro Phe Ser Cys Pro Glu Cys
                 485                 490                 495

 Asn Leu Gln Phe Ala Arg Leu Asp Asn Leu Lys Ala His Leu Lys
                 500                 505                 510

 Ile His Ser Lys Glu Lys His Ala Ser Asp Ala Ser Ser Ile Ser
                 515                 520                 525

 Gly Ser Ser Asn Thr Glu Glu Val Arg Asn Ile Leu Gln Leu Gln
                 530                 535                 540

 Pro Tyr Gln Leu Ser Thr Ser Gly Glu Gln Glu Ile Gln Leu Leu
                 545                 550                 555

 Val Thr Asp Ser Val His Asn Ile Asn Phe Met Pro Gly Pro Ser
                 560                 565                 570

 Gln Gly Ile Ser Ile Val Thr Ala Glu Ser Ser Gln Asn Met Thr
                 575                 580                 585

 Ala Asp Gln Ala Ala Asn Leu Thr Leu Leu Thr Gln Gln Pro Glu
                 590                 595                 600

 Gln Leu Gln Asn Leu Ile Leu Ser Ala Gln Gln Glu Gln Thr Glu
                 605                 610                 615

 His Ile Gln Ser Leu Asn Met Ile Glu Ser Gln Met Gly Pro Ser
                 620                 625                 630

 Gln Thr Glu Pro Val His Val Ile Thr Leu Ser Lys Glu Thr Leu
                 635                 640                 645

 Glu His Leu His Ala His Gln Glu Gln Thr Glu Glu Leu His Leu
                 650                 655                 660

 Ala Thr Ser Thr Ser Asp Pro Ala Gln His Leu Gln Leu Thr Gln
                 665                 670                 675

 Glu Pro Gly Pro Pro Pro Pro Thr His His Val Pro Gln Pro Thr
                 680                 685                 690

 Pro Leu Gly Gln Glu Gln Ser
                 695

<210> 1337
<211> 1086
<212> DNA
<213> Homo sapien

<400> 1337
 ccccggccca caagcccctg cagggagcgg gcccgggcgg cgcgcgatcg 50

 aggtcgggtc gccgtccagc ctgcagcatg agcgccccca gcgcgacccc 100

 catcttcgcg cccggcgaga actgcagccc cgcgtggggg gcggcgcccg 150

 cggcctacga cgcagcggac acgcacctgc gcatcctggg caagccggtg 200

 atggagcgct gggagacccc ctatatgcac gcgctggccg ccgccgcctc 250

 ctccaaaggg ggccgggtcc tggaggtggg ctttggcatg gccatcgcag 300

 cgtcaaaggt gcaggaggcg cccattgatg agcattggat catcgagtgc 350

 aatgacggcg tcttccagcg gctccgggac tgggccccac ggcagacaca 400

 caaggtcatc cccttgaaag gcctgtggga ggatgtggca cccaccctgc 450

 ctgacggtca ctttgatggg atcctgtacg acacgtaccc actctcggag 500

 gagacctggc acacacacca gttcaacttc atcaagaacc acgcctttcg 550

 cctgctgaag ccggggggcg tcctcaccta ctgcaacctc acctcctggg 600

 gggagctgat gaagtccaag tactcagaca tcaccatcat gtttgaggag 650

 acgcaggtgc ccgcgctgct ggaggccggc ttccggaggg agaacatccg 700

 tacggaggtg atggcgctgg tcccaccggc cgactgccgc tactacgcct 750

 tcccacagat gatcacgccc ctggtgacca aaggctgagc ccccaccccg 800

 gcccggccac acccatgccc tcctccgtgc cttcctggcc gggagtccag 850

 ggtgtcgcac cagccctggg ctgatcccag ctgtgtgtca ccagaagctt 900

 tcccggcttc tctgtgaggg gtcccaccag cccagggctg atcccagctg 950

 tgtgtcacca gcagctttcc cagcttctct gtgagggtca ctgctgccca 1000

 ctgcagggtc cctgaggtga agtaaacgcc ggcgctgggc ttggccagtc 1050

 ggcagtgaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 1086

<210> 1338
<211> 236
<212> PRT
<213> Homo sapien

<400> 1338
 Met Ser Ala Pro Ser Ala Thr Pro Ile Phe Ala Pro Gly Glu Asn
   1               5                  10                  15

 Cys Ser Pro Ala Trp Gly Ala Ala Pro Ala Ala Tyr Asp Ala Ala
                  20                  25                  30

 Asp Thr His Leu Arg Ile Leu Gly Lys Pro Val Met Glu Arg Trp
                  35                  40                  45

 Glu Thr Pro Tyr Met His Ala Leu Ala Ala Ala Ala Ser Ser Lys
                  50                  55                  60

 Gly Gly Arg Val Leu Glu Val Gly Phe Gly Met Ala Ile Ala Ala
                  65                  70                  75

 Ser Lys Val Gln Glu Ala Pro Ile Asp Glu His Trp Ile Ile Glu
                  80                  85                  90

 Cys Asn Asp Gly Val Phe Gln Arg Leu Arg Asp Trp Ala Pro Arg
                  95                 100                 105

 Gln Thr His Lys Val Ile Pro Leu Lys Gly Leu Trp Glu Asp Val
                 110                 115                 120

 Ala Pro Thr Leu Pro Asp Gly His Phe Asp Gly Ile Leu Tyr Asp
                 125                 130                 135

 Thr Tyr Pro Leu Ser Glu Glu Thr Trp His Thr His Gln Phe Asn
                 140                 145                 150

 Phe Ile Lys Asn His Ala Phe Arg Leu Leu Lys Pro Gly Gly Val
                 155                 160                 165

 Leu Thr Tyr Cys Asn Leu Thr Ser Trp Gly Glu Leu Met Lys Ser
                 170                 175                 180

 Lys Tyr Ser Asp Ile Thr Ile Met Phe Glu Glu Thr Gln Val Pro
                 185                 190                 195

 Ala Leu Leu Glu Ala Gly Phe Arg Arg Glu Asn Ile Arg Thr Glu
                 200                 205                 210

 Val Met Ala Leu Val Pro Pro Ala Asp Cys Arg Tyr Tyr Ala Phe
                 215                 220                 225

 Pro Gln Met Ile Thr Pro Leu Val Thr Lys Gly
                 230                 235

<210> 1339
<211> 2937
<212> DNA
<213> Homo sapien

<400> 1339
 caatttcaga gtgggatatc agatctttag tgtgaagata catctacatt 50

 aaaccaggaa tcactagaac tgacatttgg acaagaaaat ttggaaaatt 100

 ttaaaactgt gaaggttgat catggaaatt aaagaggaag gggcatcaga 150

 agaagggcag cactttcttc ctacagccca ggccaatgat cccggggact 200

 gtcagttcac aagtatccag aagactccaa atgaaccgca gttggaattc 250

 atccttgcat gcaaggatct cgtggctcct gtccgtgatc gtaaactgaa 300

 tacactggtg cagatctccg taatccaccc cgtggagcag agtctgacaa 350

 gatactccag caccgaaatt gtggagggaa caagggaccc actgtttttg 400

 actggtgtca cattcccatc tgagtatccc atctatgagg agaccaaaat 450

 aaaactaaca gtctatgatg tcaaggataa gtctcatgac accgttcgaa 500

 ccagtgtcct accagaacat aaggatcccc cgccagaagt tggccgaagt 550

 ttcttgggct atgccagttt taaagtggga gagctgctga agtcaaagga 600

 gcaattgctg gtcctgagcc tgagaacttc agatggtggc aaagtggttg 650

 gcaccataga agtcagtgtc gtgaagatgg gggagattga ggatggggaa 700

 gccgaccaca tcaccacaga tgtacaggga caaaagtgtg ccctggtatg 750

 tgaatgtaca gccccggaaa gtgtgagcgg aaaagataac ttaccttttt 800

 tgaattcagt gttaaagaac ccagtatgta aattatatag atttcccaca 850

 tctgacaata agtggatgcg aattcgagag cagatgtcag agagcattct 900

 ttcctttcat attcctaagg aattgatttc ccttcacatt aaagaagatt 950

 tgtgcagaaa ccaggagata aaagaacttg gtgagctttc tccacattgg 1000

 gacaatctgc gaaaaaatgt ccttacgcac tgtgatcaaa tggtgaatat 1050

 gttccaagac attctgacag aacttgccaa ggaaacaggg tcctctttca 1100

 aatcaagcag cagcaaagga gagaaaacat tagaatttgt tccaataaat 1150

 ctacatctgc aaagaatgca ggtacacagc cctcacttga aagatgctct 1200

 ctacgatgtc atcactgtgg gagccccagc tgcccatttt cagggattta 1250

 agaatggtgg tcttcggaag ctactccata gatttgaaac agaaagaaga 1300

 aataccggat accagtttat ttactattca cctgaaaaca cagccaaagc 1350

 aaaggaagtt ctcagcaaca tcaatcaact acaacctctt atagcaaccc 1400

 atgcagacct actgcttaat tctgcaagcc agcattctcc agacagcttg 1450

 aagaattctt taaagatgct ttcagaaaaa acagagcttt ttgtacatgc 1500

 cttcaaggat caacttgtca ggagtgctct tttagcactc tacactgcaa 1550

 ggccaggagg cattcttaag aagccaccct ctcctaagag cagcacagag 1600

 gagagcagtc cccaagacca acccccagtg atgagagggc aggactccat 1650

 accacatcat tcagactatg atgaggaaga gtgggacagg gtgtgggcca 1700

 atgtggggaa gagcctgaac tgcattattg ctatggtgga caaactgatt 1750

 gaaagagatg gtggcagtga aggcagtggt ggcaacaatg atggagaaaa 1800

 ggaaccttca ttaacagatg ccattccctc tcacccaaga gaggactggt 1850

 atgaacagtt gtatcccctc atccttaccc tgaaggactg catgggagaa 1900

 gtggtgaacc gagccaagca gtccctgaca tttgtgctcc ttcaggaact 1950

 tgcgtacagc ttgccccagt gtctgatgct gacgctaaga agagacatcg 2000

 tcttcagcca agcacttgct ggattggttt gtggttttat catcaaatta 2050

 cagacaagtc tgtatgaccc aggcttccta cagcagcttc acacagtggg 2100

 gttgatagta caatatgaag gattgttaag tacatacagc gatgaaattg 2150

 gaatgttaga ggacatgccc gttggcattt ccgatttaaa gaaagttgca 2200

 tttaaaataa ttgaagccaa atccaatgat gtattgccag ttataacagg 2250

 aagacgagaa cattacgtgg tagaggtcaa gcttccagcc agaatgtttg 2300

 agtcactacc tctacagatt aaagaaggac agttgcttca tgtgtatcca 2350

 gtacttttta atgttggaat caatgaacag caaactctgg ctgaaaggtt 2400

 tggagatgtc tctttgcaag aaagtattaa tcaggaaaac ttcgaacttc 2450

 tacaagaata ttacaagata tttatggaaa agatgcctcc tgattatatt 2500

 tcacattttc aggaacaaaa tgatttaaaa gcattgctag aaaatctcct 2550

 tcaaaatatc caatccaaaa aaagaaagaa tgtagaaatt atgtggctgg 2600

 ctgcaacgat ttgccgcaaa ctgaatggta ttcgtttcac ctgttgtaaa 2650

 agtgccaaag acaggacatc gatgtcagtg acacttgaac aatgctcaat 2700

 cttgagagat gagcaccagt tacacaagga cttctttatc cgagcgctgg 2750

 attgcatgag aagagaagga tgccgcatag agaatgtact gaagaatatc 2800

 aaatgcagaa agtatgcttt caacatgcta cagctgatgg ctttccccaa 2850

 gtactacaga cctccagagg ggacttatgg aaaagctgac acctaagttt 2900

 accaacatgt taataaacag gaacacaaat acatttc 2937

<210> 1340
<211> 924
<212> PRT
<213> Homo sapien

<400> 1340
 Met Glu Ile Lys Glu Glu Gly Ala Ser Glu Glu Gly Gln His Phe
   1               5                  10                  15

 Leu Pro Thr Ala Gln Ala Asn Asp Pro Gly Asp Cys Gln Phe Thr
                  20                  25                  30

 Ser Ile Gln Lys Thr Pro Asn Glu Pro Gln Leu Glu Phe Ile Leu
                  35                  40                  45

 Ala Cys Lys Asp Leu Val Ala Pro Val Arg Asp Arg Lys Leu Asn
                  50                  55                  60

 Thr Leu Val Gln Ile Ser Val Ile His Pro Val Glu Gln Ser Leu
                  65                  70                  75

 Thr Arg Tyr Ser Ser Thr Glu Ile Val Glu Gly Thr Arg Asp Pro
                  80                  85                  90

 Leu Phe Leu Thr Gly Val Thr Phe Pro Ser Glu Tyr Pro Ile Tyr
                  95                 100                 105

 Glu Glu Thr Lys Ile Lys Leu Thr Val Tyr Asp Val Lys Asp Lys
                 110                 115                 120

 Ser His Asp Thr Val Arg Thr Ser Val Leu Pro Glu His Lys Asp
                 125                 130                 135

 Pro Pro Pro Glu Val Gly Arg Ser Phe Leu Gly Tyr Ala Ser Phe
                 140                 145                 150

 Lys Val Gly Glu Leu Leu Lys Ser Lys Glu Gln Leu Leu Val Leu
                 155                 160                 165

 Ser Leu Arg Thr Ser Asp Gly Gly Lys Val Val Gly Thr Ile Glu
                 170                 175                 180

 Val Ser Val Val Lys Met Gly Glu Ile Glu Asp Gly Glu Ala Asp
                 185                 190                 195

 His Ile Thr Thr Asp Val Gln Gly Gln Lys Cys Ala Leu Val Cys
                 200                 205                 210

 Glu Cys Thr Ala Pro Glu Ser Val Ser Gly Lys Asp Asn Leu Pro
                 215                 220                 225

 Phe Leu Asn Ser Val Leu Lys Asn Pro Val Cys Lys Leu Tyr Arg
                 230                 235                 240

 Phe Pro Thr Ser Asp Asn Lys Trp Met Arg Ile Arg Glu Gln Met
                 245                 250                 255

 Ser Glu Ser Ile Leu Ser Phe His Ile Pro Lys Glu Leu Ile Ser
                 260                 265                 270

 Leu His Ile Lys Glu Asp Leu Cys Arg Asn Gln Glu Ile Lys Glu
                 275                 280                 285

 Leu Gly Glu Leu Ser Pro His Trp Asp Asn Leu Arg Lys Asn Val
                 290                 295                 300

 Leu Thr His Cys Asp Gln Met Val Asn Met Phe Gln Asp Ile Leu
                 305                 310                 315

 Thr Glu Leu Ala Lys Glu Thr Gly Ser Ser Phe Lys Ser Ser Ser
                 320                 325                 330

 Ser Lys Gly Glu Lys Thr Leu Glu Phe Val Pro Ile Asn Leu His
                 335                 340                 345

 Leu Gln Arg Met Gln Val His Ser Pro His Leu Lys Asp Ala Leu
                 350                 355                 360

 Tyr Asp Val Ile Thr Val Gly Ala Pro Ala Ala His Phe Gln Gly
                 365                 370                 375

 Phe Lys Asn Gly Gly Leu Arg Lys Leu Leu His Arg Phe Glu Thr
                 380                 385                 390

 Glu Arg Arg Asn Thr Gly Tyr Gln Phe Ile Tyr Tyr Ser Pro Glu
                 395                 400                 405

 Asn Thr Ala Lys Ala Lys Glu Val Leu Ser Asn Ile Asn Gln Leu
                 410                 415                 420

 Gln Pro Leu Ile Ala Thr His Ala Asp Leu Leu Leu Asn Ser Ala
                 425                 430                 435

 Ser Gln His Ser Pro Asp Ser Leu Lys Asn Ser Leu Lys Met Leu
                 440                 445                 450

 Ser Glu Lys Thr Glu Leu Phe Val His Ala Phe Lys Asp Gln Leu
                 455                 460                 465

 Val Arg Ser Ala Leu Leu Ala Leu Tyr Thr Ala Arg Pro Gly Gly
                 470                 475                 480

 Ile Leu Lys Lys Pro Pro Ser Pro Lys Ser Ser Thr Glu Glu Ser
                 485                 490                 495

 Ser Pro Gln Asp Gln Pro Pro Val Met Arg Gly Gln Asp Ser Ile
                 500                 505                 510

 Pro His His Ser Asp Tyr Asp Glu Glu Glu Trp Asp Arg Val Trp
                 515                 520                 525

 Ala Asn Val Gly Lys Ser Leu Asn Cys Ile Ile Ala Met Val Asp
                 530                 535                 540

 Lys Leu Ile Glu Arg Asp Gly Gly Ser Glu Gly Ser Gly Gly Asn
                 545                 550                 555

 Asn Asp Gly Glu Lys Glu Pro Ser Leu Thr Asp Ala Ile Pro Ser
                 560                 565                 570

 His Pro Arg Glu Asp Trp Tyr Glu Gln Leu Tyr Pro Leu Ile Leu
                 575                 580                 585

 Thr Leu Lys Asp Cys Met Gly Glu Val Val Asn Arg Ala Lys Gln
                 590                 595                 600

 Ser Leu Thr Phe Val Leu Leu Gln Glu Leu Ala Tyr Ser Leu Pro
                 605                 610                 615

 Gln Cys Leu Met Leu Thr Leu Arg Arg Asp Ile Val Phe Ser Gln
                 620                 625                 630

 Ala Leu Ala Gly Leu Val Cys Gly Phe Ile Ile Lys Leu Gln Thr
                 635                 640                 645

 Ser Leu Tyr Asp Pro Gly Phe Leu Gln Gln Leu His Thr Val Gly
                 650                 655                 660

 Leu Ile Val Gln Tyr Glu Gly Leu Leu Ser Thr Tyr Ser Asp Glu
                 665                 670                 675

 Ile Gly Met Leu Glu Asp Met Pro Val Gly Ile Ser Asp Leu Lys
                 680                 685                 690

 Lys Val Ala Phe Lys Ile Ile Glu Ala Lys Ser Asn Asp Val Leu
                 695                 700                 705

 Pro Val Ile Thr Gly Arg Arg Glu His Tyr Val Val Glu Val Lys
                 710                 715                 720

 Leu Pro Ala Arg Met Phe Glu Ser Leu Pro Leu Gln Ile Lys Glu
                 725                 730                 735

 Gly Gln Leu Leu His Val Tyr Pro Val Leu Phe Asn Val Gly Ile
                 740                 745                 750

 Asn Glu Gln Gln Thr Leu Ala Glu Arg Phe Gly Asp Val Ser Leu
                 755                 760                 765

 Gln Glu Ser Ile Asn Gln Glu Asn Phe Glu Leu Leu Gln Glu Tyr
                 770                 775                 780

 Tyr Lys Ile Phe Met Glu Lys Met Pro Pro Asp Tyr Ile Ser His
                 785                 790                 795

 Phe Gln Glu Gln Asn Asp Leu Lys Ala Leu Leu Glu Asn Leu Leu
                 800                 805                 810

 Gln Asn Ile Gln Ser Lys Lys Arg Lys Asn Val Glu Ile Met Trp
                 815                 820                 825

 Leu Ala Ala Thr Ile Cys Arg Lys Leu Asn Gly Ile Arg Phe Thr
                 830                 835                 840

 Cys Cys Lys Ser Ala Lys Asp Arg Thr Ser Met Ser Val Thr Leu
                 845                 850                 855

 Glu Gln Cys Ser Ile Leu Arg Asp Glu His Gln Leu His Lys Asp
                 860                 865                 870

 Phe Phe Ile Arg Ala Leu Asp Cys Met Arg Arg Glu Gly Cys Arg
                 875                 880                 885

 Ile Glu Asn Val Leu Lys Asn Ile Lys Cys Arg Lys Tyr Ala Phe
                 890                 895                 900

 Asn Met Leu Gln Leu Met Ala Phe Pro Lys Tyr Tyr Arg Pro Pro
                 905                 910                 915

 Glu Gly Thr Tyr Gly Lys Ala Asp Thr
                 920

<210> 1341
<211> 8220
<212> DNA
<213> Homo sapien

<400> 1341
 agaggctgcg gtgagtccgc cagccccagc tgctcctcct caagccccca 50

 aggcccttcg gcgggcccct gctgaaagac cggcatgccc tattctgtgg 100

 gcttccgcga agccgatgct gctaccagct ttctgagagc agcaagatca 150

 ggtaacttgg acaaagcttt ggatcacctg cggaatgggg tagatattaa 200

 cacctgtaac cagaatgggt tgaatggctt gcatctggct tctaaggaag 250

 gccatgtgaa aatggtggtt gaacttctgc acaaagaaat cattctagaa 300

 acgacaacca agaaggggaa cacggccctg cacatcgctg ctctagccgg 350

 gcaggatgag gtggtccggg agcttgtcaa ctatggagcc aacgtcaatg 400

 cccagtcaca gaaaggtttt acacccctgt acatggcagc acaagagaac 450

 cacttggaag tggttaagtt tttactggaa aatggagcta accagaatgt 500

 agccacagaa gacggcttca cgcctctggc ggtagccctg cagcagggcc 550

 atgagaacgt cgtcgcgcac ctcatcaact acggcaccaa ggggaaggtg 600

 cgcctcccgg ccctgcacat cgcggcccgc aacgacgaca cgcgcacggc 650

 tgcggtgctg ctgcagaacg accccaaccc ggacgtgctt tccaagacgg 700

 gattcacgcc cctgcacatt gcggctcact acgagaacct caacgtggcc 750

 cagttgctcc tcaacagagg agccagcgtc aatttcacac cacagaacgg 800

 catcacgcca ctgcacatcg cctcccgcag gggcaacgtg atcatggtgc 850

 ggctgctgct ggatcgggga gcccagatag aaaccaagac caaggacgaa 900

 ttgacacctc tccactgtgc agctcgaaat gggcacgtgc gaatctcaga 950

 gatcctgctg gaccacgggg caccaatcca agccaaaacc aagaacggcc 1000

 tgtccccaat tcacatggcg gctcagggag accacctcga ctgtgtccgg 1050

 ctcctgttgc aatacgacgc agagatagac gacatcaccc tggaccacct 1100

 gaccccactc cacgtggctg cccactgtgg acaccacagg gtggctaagg 1150

 tccttctgga taaaggggcc aaacccaact ccagagccct gaatggcttt 1200

 acccccttac acatcgcctg caaaaagaac cacgtccgtg tcatggagct 1250

 gctgctgaag acgggagcct cgatcgacgc ggtcaccgag tctggcctga 1300

 cacctctcca cgtggcctcc ttcatggggc accttcccat cgtgaagaac 1350

 ctcctgcagc ggggggcgtc gcccaacgtc tccaacgtga aagtggagac 1400

 cccgctacac atggcagcca gagccgggca cacggaagtg gccaaatatt 1450

 tactccagaa caaagccaaa gtcaatgcca aggccaagga tgaccagacc 1500

 ccacttcact gtgcagctcg catcggccac acaaacatgg tgaagctcct 1550

 gctggaaaat aacgccaacc ccaacctggc caccaccgcc gggcacaccc 1600

 ccctgcacat tgcagcccgt gagggccatg tggaaacagt cctggccctt 1650

 ctggaaaagg aagcatccca ggcctgcatg accaagaaag gatttacccc 1700

 tctgcacgtg gcggccaagt acgggaaggt gcgggtggca gagctgctgc 1750

 tggagcggga cgcacacccg aatgctgccg gaaaaaatgg cctgaccccc 1800

 ctgcacgtgg ccgtccatca caacaacctg gacatcgtca agctgctgct 1850

 tccccggggc ggctccccgc acagccctgc ctggaatggc tacacccctt 1900

 tgcacatcgc tgccaagcag aaccaggtgg aggtggcccg tagtctgctg 1950

 cagtatgggg gctcagcaaa cgccgagtcg gtgcaaggtg tgacgcccct 2000

 tcacctggcc gcccaggagg gccacgcaga gatggtggct ctgctgctct 2050

 cgaaacaagc caatggcaac ctggggaaca agagcggact cactcccctc 2100

 catctggtag cacaagaagg ccacgttcca gtggcagatg tgctgatcaa 2150

 acacggtgtc atggtggacg ccaccacccg gatgggctac actcccctcc 2200

 atgtggccag tcactatgga aacatcaagc tggtgaagtt tctgctgcag 2250

 caccaggcag atgtcaatgc caagaccaag ctaggataca gccccctgca 2300

 ccaggcagcc cagcagggac acacagacat cgtgactctg cttctgaaaa 2350

 acggtgcttc cccaaacgag gtcagctcgg atggaaccac acctctggcc 2400

 atagccaagc gcttgggcta catttctgtc accgacgtgc tcaaggtcgt 2450

 cacggatgaa accagtttcg tgttagtcag tgataagcat cgaatgagtt 2500

 tccctgagac agttgatgag atcctggatg tctcggaaga tgaaggggaa 2550

 gaactcatca gcttcaaggc tgagaggcgg gattccaggg atgttgatga 2600

 agagaaggag ctgctggatt ttgtgccgaa gctagaccaa gtggtggaat 2650

 ctccagccat ccccaggatt ccctgtgcca tgcctgagac agtggtgatc 2700

 aggtcagaag agcaggagca ggcatctaaa gagtatgatg aggactccct 2750

 catccccagc agcccggcca ccgagacctc agacaacatc agcccggtgg 2800

 ccagcccggt gcatacaggg tttctggtga gcttcatggt tgacgcccgg 2850

 ggtggttcca tgagaggaag tcgccacaac ggcctgcgag tggtgatccc 2900

 gccacggacg tgcgcagcgc ccacccgcat cacctgccgc ctggtcaagc 2950

 cccagaagct cagcacgccg cccccactgg ccgaggagga gggcctggcc 3000

 agcaggatca tagcactggg gcccacgggg gcacagttcc tgagccctgt 3050

 aatcgtggag atcccgcact ttgcctccca tggccgtgga gaccgcgagc 3100

 tcgtggttct gaggagcgaa aacggctccg tgtggaagga gcacaggagc 3150

 cgctatggag agagctacct ggatcagatc ctcaacggga tggacgaaga 3200

 gctggggagc ctggaggagc tagagaagaa gagggtgtgc cgaatcatca 3250

 ccaccgactt cccgctgtac ttcgtgatca tgtcacggct ctgccaggac 3300

 tacgacatca tcggtcccga agggggctcc ctgaagagca agctggtgcc 3350

 cctggtacag gcaacgttcc cggagaatgc cgtcaccaag agagtgaagc 3400

 tggctctgca ggcccagcct gtcccggatg agcttgtcac taagctcctg 3450

 ggcaaccagg ccacattcag ccccattgtc accgtggagc cccggcgccg 3500

 gaagttccac cgccccattg ggcttcggat cccactacct ccttcctgga 3550

 ccgacaaccc gagggacagt ggggagggag acaccaccag cctgcgcctg 3600

 ctttgcagcg tcattggagg aacagaccaa gcccagtggg aagacataac 3650

 aggaaccacc aaacttgtat atgccaacga gtgcgccaac ttcaccacca 3700

 atgtctctgc caggttttgg ctgtcggact gtcctcggac tgctgaggct 3750

 gtgaactttg ccaccctgct gtacaaagag ctcactgcag tgccctacat 3800

 ggccaaattc gtcatctttg ccaagatgaa tgacccccga gaggggcgcc 3850

 tgcgctgcta ctgcatgaca gatgataaag tggacaagac cctggagcag 3900

 catgagaact tcgtggaggt ggcccggagc agggacatag aggtgttgga 3950

 aggaatgtcc ctgtttgcag aactctctgg gaacctggtg cctgtgaaga 4000

 aagctgccca gcagcggagc ttccacttcc agtcatttcg ggagaaccgt 4050

 ctggccatgc ctgtaaaggt gagggacagc agtcgagagc cgggagggtc 4100

 cctgtcgttt ctgcgcaagg cgatgaagta cgaggacacc cagcacattc 4150

 tctgccacct gaacatcacc atgcccccct gcgctaaggg aagtggagcc 4200

 gaagatagga gaaggacccc gacgcccctg gccctgcgat acagcattct 4250

 cagtgagtcc acaccaggtt ctctcagtgg gacagagcag gcagagatga 4300

 agatggctgt tatctcagag cacctcggtc tcagctgggc agagttggcc 4350

 cgggagctgc agttcagtgt ggaagacatc aacaggatcc gagtggaaaa 4400

 tcccaactcc ctgttggagc agagtgtggc cttgctgaac ctctgggtca 4450

 tccgtgaagg ccaaaacgca aacatggaga atctgtacac agccctgcag 4500

 agcattgacc gtggcgagat cgtgaacatg ctggagggtt ccggccgaca 4550

 gagccgcaac ttgaagccag acaggcggca caccgaccgc gactactcgc 4600

 tgtcaccctc ccagatgaat ggttactcct cactgcagga cgagctgctg 4650

 tcccctgcct ccctgggctg tgcactttcc tctccgctac gtgcagacca 4700

 gtactggaat gaggtggccg tcctagacgc catccccttg gcggccacgg 4750

 agcatgacac catgctggag atgtctgaca tgcaggtgtg gtctgcgggc 4800

 ctcacgcctt ctctggtcac tgctgaggac tcctctctgg agtgtagcaa 4850

 ggctgaggac tctgatgcca caggtcacga gtggaagttg gagggggcac 4900

 tctcagagga accgcggggc cccgagttgg gctctctgga acttgtggag 4950

 gacgacacag tggattcaga tgccacaaat ggccttatcg atttgcttga 5000

 acaggaggaa ggtcagaggt cagaagagaa gctgccaggt tctaagaggc 5050

 aggatgacgc gacaggtgca gggcaggact cagagaatga agtgtctctt 5100

 gtttcaggcc atcagagggg gcaagcccga atcacacatt cccccaccgt 5150

 gagtcaggtg acggagagga gtcaggacag actgcaggac tgggatgcag 5200

 acggctcgat tgtctcatac ctgcaagatg ctgcacaagg ttcctggcaa 5250

 gaggaggtca cgcaaggtcc acactcattc cagggaacaa gtaccatgac 5300

 tgaagggcta gagcccggtg gatctcagga gtacgagaag gtcctggtgt 5350

 ctgtaagtga gcacacgtgg acagaacagc ccgaggctga gagctcccag 5400

 gccgacaggg accggaggca gcaaggccaa gaagagcagg tgcaggaggc 5450

 caagaacacc ttcacccaag tggtgcaggg gaatgagttt cagaatattc 5500

 caggggagca ggtgacagag gagcaattca cggatgagca gggcaacatt 5550

 gtcaccaaga agatcattcg caaggtggtt cgacagatag acttgtccag 5600

 cgccgatgcc gcccaggagc acgaggaggt gactgtagag gggcccctgg 5650

 aggatcccag tgagctggag gtcgatattg attactttat gaaacactcc 5700

 aaggatcaca cctcgacacc caacccctga accccacaca ctctgccatg 5750

 cacacaggag gagagctgga cctgagggcc accgcagcgg tgcacacatt 5800

 cctctgggct gacggcatga cctctgtaag ggactcctgc tagtcccctc 5850

 ttggcatgaa tgactgactg tagacgcatg acctccaggc ttcaatcctg 5900

 cctcttgcaa tgacagctga tctgtcggaa ccaggacaca aaagcagcaa 5950

 gaagcgggga gagagaggga tagaaaacaa gcgcaggaga gcctgcgaac 6000

 gcaaaagtga atgagggctt tttgtggctg gggatgggtt ttggttttgg 6050

 ggtttttttt ttaaattgtt ttgacttcgt acagggtact ttttcccaac 6100

 ctcatctgtc agaaatccat gtgggcttcc tggaaagaaa aaaaaaaaaa 6150

 agaaaactag gcatgaaatc agtttaacac cttaatctta agccatgtcc 6200

 tcatctgccc accctcccca acccacatac ctccattcca cttgtgacac 6250

 cccctcgact ccctggtgac gctcctccca gatcgctcta catgacattc 6300

 aggacacaca cacacacaca cacacacaca ccactcgcct ccactgaatc 6350

 tacacacaga ttttactgtg acttctgaag ctgtggataa attggaattt 6400

 tttatgttgt ctctctctct gccaatttca atacgaatca tcttccaatg 6450

 gaaaatcatt accttgaaga gtgcattcgg ggttccttgt gttagggact 6500

 taagaatctg aggcgcgagg acccccaggc ttacctgtag gactcaaagg 6550

 gagccaggac cccatctgaa agggtctcct ctctcagttg ggggacaggc 6600

 cggtggctga cccaggattg caccagcatg tccatagaga agaggttttc 6650

 tatgtcttca agcactatat catagtccgt gttcaaagtg taaactgtac 6700

 agtaatcagc cttgtgtata tgaaaaacaa taaatactat gcaaaccaat 6750

 agaaacattt agcagtacgt acagagcctg acagcgcagc tcctgaggac 6800

 ttctgcggct gcaggagaag gagctgtggc ctgtctttca gtgaaagagg 6850

 aaggaaagga gtagggctag tgaatgtatc tgccaggtct tagaagtcag 6900

 gaccacccag ggtctcccag agtgaacttg gtgctctaag tccaggcagc 6950

 ctgcaggctg gggaccctgg gtgcaggtgc caggctcgag gctgttccct 7000

 gtcctgcctc agtgcctccc ctctgcccag cccctgtggc ctcttggaga 7050

 ggcgagccag ggggctcccc ggaccgcatg gccggtgaga gtagagtcgg 7100

 aggcggagag cctggacgcc cagaggccgg ggccaggctc tgggtcaagg 7150

 caggaaggag acagacagct ggcagttcct cgcctcggtg ccatcaggga 7200

 ggagccttaa gttccactag agcctccggc ccagggaggc cagaatcagc 7250

 acaatcccgg ccccgccctc gcggcgggcg cccccagggc caggagagag 7300

 agacagggct ggctcctctc gcccctggag ccgcggtgtg gacggcccgg 7350

 ccccgtccgc cccgccgctc tgcgggagtg tccttcggga cacacttaaa 7400

 ccttccaagt agcacagaag ccccctccac gtcagagccc cctggccgcg 7450

 gggcctgtga gcggagaggg gccctgcttc ccacacaaat ccgccccggt 7500

 gcacccccgg ccaggcaggc cccggggcgg cctaggcgcc ttgtcggccg 7550

 ggggtggggc tgcttttgct tcctttagag gggcgggcag ggagaggaag 7600

 ctctagctcc gggcctgagt ttccccgagg ctgcgtcgga ggagctgcag 7650

 ggcgagcccg gacggctgcc gtctccgcca gaggccaccc cggcccggcc 7700

 tccaggcaga ggcgcccccc tccatcctcc cccatcccgg gggccacggc 7750

 aggggggccg cacagcgcgg ctgggaccga ttcggtgacg gcccaaggaa 7800

 gctgggcgca gggctcgcct ctcccgcctc gatcctgcac cttcctctcc 7850

 caggtcgctg ctgcagccaa cccagtagcc cccttagcgc ccccgcggac 7900

 cccgcagctc cagactccgc tttggcacct ctgctccggc tggcatggct 7950

 gcacgctccg gctgctagta ggagccgtta ggggaggagt ttggggtctc 8000

 cacacgatgc ctagagaatg ctgcagtctg cacattagac gctttttaga 8050

 agttttgaaa ttaccttgat ttttttaatt gttatgaaaa tggatctttt 8100

 cttgactctc ccacatgctc tgttatggga gagaatcccc taccctactc 8150

 tgatgtatag accattctcc cttcaccagc cgaaccaatg tcaaaattaa 8200

 taaagaaatg gactaaggca 8220

<210> 1342
<211> 1881
<212> PRT
<213> Homo sapien

<400> 1342
 Met Pro Tyr Ser Val Gly Phe Arg Glu Ala Asp Ala Ala Thr Ser
   1               5                  10                  15

 Phe Leu Arg Ala Ala Arg Ser Gly Asn Leu Asp Lys Ala Leu Asp
                  20                  25                  30

 His Leu Arg Asn Gly Val Asp Ile Asn Thr Cys Asn Gln Asn Gly
                  35                  40                  45

 Leu Asn Gly Leu His Leu Ala Ser Lys Glu Gly His Val Lys Met
                  50                  55                  60

 Val Val Glu Leu Leu His Lys Glu Ile Ile Leu Glu Thr Thr Thr
                  65                  70                  75

 Lys Lys Gly Asn Thr Ala Leu His Ile Ala Ala Leu Ala Gly Gln
                  80                  85                  90

 Asp Glu Val Val Arg Glu Leu Val Asn Tyr Gly Ala Asn Val Asn
                  95                 100                 105

 Ala Gln Ser Gln Lys Gly Phe Thr Pro Leu Tyr Met Ala Ala Gln
                 110                 115                 120

 Glu Asn His Leu Glu Val Val Lys Phe Leu Leu Glu Asn Gly Ala
                 125                 130                 135

 Asn Gln Asn Val Ala Thr Glu Asp Gly Phe Thr Pro Leu Ala Val
                 140                 145                 150

 Ala Leu Gln Gln Gly His Glu Asn Val Val Ala His Leu Ile Asn
                 155                 160                 165

 Tyr Gly Thr Lys Gly Lys Val Arg Leu Pro Ala Leu His Ile Ala
                 170                 175                 180

 Ala Arg Asn Asp Asp Thr Arg Thr Ala Ala Val Leu Leu Gln Asn
                 185                 190                 195

 Asp Pro Asn Pro Asp Val Leu Ser Lys Thr Gly Phe Thr Pro Leu
                 200                 205                 210

 His Ile Ala Ala His Tyr Glu Asn Leu Asn Val Ala Gln Leu Leu
                 215                 220                 225

 Leu Asn Arg Gly Ala Ser Val Asn Phe Thr Pro Gln Asn Gly Ile
                 230                 235                 240

 Thr Pro Leu His Ile Ala Ser Arg Arg Gly Asn Val Ile Met Val
                 245                 250                 255

 Arg Leu Leu Leu Asp Arg Gly Ala Gln Ile Glu Thr Lys Thr Lys
                 260                 265                 270

 Asp Glu Leu Thr Pro Leu His Cys Ala Ala Arg Asn Gly His Val
                 275                 280                 285

 Arg Ile Ser Glu Ile Leu Leu Asp His Gly Ala Pro Ile Gln Ala
                 290                 295                 300

 Lys Thr Lys Asn Gly Leu Ser Pro Ile His Met Ala Ala Gln Gly
                 305                 310                 315

 Asp His Leu Asp Cys Val Arg Leu Leu Leu Gln Tyr Asp Ala Glu
                 320                 325                 330

 Ile Asp Asp Ile Thr Leu Asp His Leu Thr Pro Leu His Val Ala
                 335                 340                 345

 Ala His Cys Gly His His Arg Val Ala Lys Val Leu Leu Asp Lys
                 350                 355                 360

 Gly Ala Lys Pro Asn Ser Arg Ala Leu Asn Gly Phe Thr Pro Leu
                 365                 370                 375

 His Ile Ala Cys Lys Lys Asn His Val Arg Val Met Glu Leu Leu
                 380                 385                 390

 Leu Lys Thr Gly Ala Ser Ile Asp Ala Val Thr Glu Ser Gly Leu
                 395                 400                 405

 Thr Pro Leu His Val Ala Ser Phe Met Gly His Leu Pro Ile Val
                 410                 415                 420

 Lys Asn Leu Leu Gln Arg Gly Ala Ser Pro Asn Val Ser Asn Val
                 425                 430                 435

 Lys Val Glu Thr Pro Leu His Met Ala Ala Arg Ala Gly His Thr
                 440                 445                 450

 Glu Val Ala Lys Tyr Leu Leu Gln Asn Lys Ala Lys Val Asn Ala
                 455                 460                 465

 Lys Ala Lys Asp Asp Gln Thr Pro Leu His Cys Ala Ala Arg Ile
                 470                 475                 480

 Gly His Thr Asn Met Val Lys Leu Leu Leu Glu Asn Asn Ala Asn
                 485                 490                 495

 Pro Asn Leu Ala Thr Thr Ala Gly His Thr Pro Leu His Ile Ala
                 500                 505                 510

 Ala Arg Glu Gly His Val Glu Thr Val Leu Ala Leu Leu Glu Lys
                 515                 520                 525

 Glu Ala Ser Gln Ala Cys Met Thr Lys Lys Gly Phe Thr Pro Leu
                 530                 535                 540

 His Val Ala Ala Lys Tyr Gly Lys Val Arg Val Ala Glu Leu Leu
                 545                 550                 555

 Leu Glu Arg Asp Ala His Pro Asn Ala Ala Gly Lys Asn Gly Leu
                 560                 565                 570

 Thr Pro Leu His Val Ala Val His His Asn Asn Leu Asp Ile Val
                 575                 580                 585

 Lys Leu Leu Leu Pro Arg Gly Gly Ser Pro His Ser Pro Ala Trp
                 590                 595                 600

 Asn Gly Tyr Thr Pro Leu His Ile Ala Ala Lys Gln Asn Gln Val
                 605                 610                 615

 Glu Val Ala Arg Ser Leu Leu Gln Tyr Gly Gly Ser Ala Asn Ala
                 620                 625                 630

 Glu Ser Val Gln Gly Val Thr Pro Leu His Leu Ala Ala Gln Glu
                 635                 640                 645

 Gly His Ala Glu Met Val Ala Leu Leu Leu Ser Lys Gln Ala Asn
                 650                 655                 660

 Gly Asn Leu Gly Asn Lys Ser Gly Leu Thr Pro Leu His Leu Val
                 665                 670                 675

 Ala Gln Glu Gly His Val Pro Val Ala Asp Val Leu Ile Lys His
                 680                 685                 690

 Gly Val Met Val Asp Ala Thr Thr Arg Met Gly Tyr Thr Pro Leu
                 695                 700                 705

 His Val Ala Ser His Tyr Gly Asn Ile Lys Leu Val Lys Phe Leu
                 710                 715                 720

 Leu Gln His Gln Ala Asp Val Asn Ala Lys Thr Lys Leu Gly Tyr
                 725                 730                 735

 Ser Pro Leu His Gln Ala Ala Gln Gln Gly His Thr Asp Ile Val
                 740                 745                 750

 Thr Leu Leu Leu Lys Asn Gly Ala Ser Pro Asn Glu Val Ser Ser
                 755                 760                 765

 Asp Gly Thr Thr Pro Leu Ala Ile Ala Lys Arg Leu Gly Tyr Ile
                 770                 775                 780

 Ser Val Thr Asp Val Leu Lys Val Val Thr Asp Glu Thr Ser Phe
                 785                 790                 795

 Val Leu Val Ser Asp Lys His Arg Met Ser Phe Pro Glu Thr Val
                 800                 805                 810

 Asp Glu Ile Leu Asp Val Ser Glu Asp Glu Gly Glu Glu Leu Ile
                 815                 820                 825

 Ser Phe Lys Ala Glu Arg Arg Asp Ser Arg Asp Val Asp Glu Glu
                 830                 835                 840

 Lys Glu Leu Leu Asp Phe Val Pro Lys Leu Asp Gln Val Val Glu
                 845                 850                 855

 Ser Pro Ala Ile Pro Arg Ile Pro Cys Ala Met Pro Glu Thr Val
                 860                 865                 870

 Val Ile Arg Ser Glu Glu Gln Glu Gln Ala Ser Lys Glu Tyr Asp
                 875                 880                 885

 Glu Asp Ser Leu Ile Pro Ser Ser Pro Ala Thr Glu Thr Ser Asp
                 890                 895                 900

 Asn Ile Ser Pro Val Ala Ser Pro Val His Thr Gly Phe Leu Val
                 905                 910                 915

 Ser Phe Met Val Asp Ala Arg Gly Gly Ser Met Arg Gly Ser Arg
                 920                 925                 930

 His Asn Gly Leu Arg Val Val Ile Pro Pro Arg Thr Cys Ala Ala
                 935                 940                 945

 Pro Thr Arg Ile Thr Cys Arg Leu Val Lys Pro Gln Lys Leu Ser
                 950                 955                 960

 Thr Pro Pro Pro Leu Ala Glu Glu Glu Gly Leu Ala Ser Arg Ile
                 965                 970                 975

 Ile Ala Leu Gly Pro Thr Gly Ala Gln Phe Leu Ser Pro Val Ile
                 980                 985                 990

 Val Glu Ile Pro His Phe Ala Ser His Gly Arg Gly Asp Arg Glu
                 995                1000                1005

 Leu Val Val Leu Arg Ser Glu Asn Gly Ser Val Trp Lys Glu His
                1010                1015                1020

 Arg Ser Arg Tyr Gly Glu Ser Tyr Leu Asp Gln Ile Leu Asn Gly
                1025                1030                1035

 Met Asp Glu Glu Leu Gly Ser Leu Glu Glu Leu Glu Lys Lys Arg
                1040                1045                1050

 Val Cys Arg Ile Ile Thr Thr Asp Phe Pro Leu Tyr Phe Val Ile
                1055                1060                1065

 Met Ser Arg Leu Cys Gln Asp Tyr Asp Ile Ile Gly Pro Glu Gly
                1070                1075                1080

 Gly Ser Leu Lys Ser Lys Leu Val Pro Leu Val Gln Ala Thr Phe
                1085                1090                1095

 Pro Glu Asn Ala Val Thr Lys Arg Val Lys Leu Ala Leu Gln Ala
                1100                1105                1110

 Gln Pro Val Pro Asp Glu Leu Val Thr Lys Leu Leu Gly Asn Gln
                1115                1120                1125

 Ala Thr Phe Ser Pro Ile Val Thr Val Glu Pro Arg Arg Arg Lys
                1130                1135                1140

 Phe His Arg Pro Ile Gly Leu Arg Ile Pro Leu Pro Pro Ser Trp
                1145                1150                1155

 Thr Asp Asn Pro Arg Asp Ser Gly Glu Gly Asp Thr Thr Ser Leu
                1160                1165                1170

 Arg Leu Leu Cys Ser Val Ile Gly Gly Thr Asp Gln Ala Gln Trp
                1175                1180                1185

 Glu Asp Ile Thr Gly Thr Thr Lys Leu Val Tyr Ala Asn Glu Cys
                1190                1195                1200

 Ala Asn Phe Thr Thr Asn Val Ser Ala Arg Phe Trp Leu Ser Asp
                1205                1210                1215

 Cys Pro Arg Thr Ala Glu Ala Val Asn Phe Ala Thr Leu Leu Tyr
                1220                1225                1230

 Lys Glu Leu Thr Ala Val Pro Tyr Met Ala Lys Phe Val Ile Phe
                1235                1240                1245

 Ala Lys Met Asn Asp Pro Arg Glu Gly Arg Leu Arg Cys Tyr Cys
                1250                1255                1260

 Met Thr Asp Asp Lys Val Asp Lys Thr Leu Glu Gln His Glu Asn
                1265                1270                1275

 Phe Val Glu Val Ala Arg Ser Arg Asp Ile Glu Val Leu Glu Gly
                1280                1285                1290

 Met Ser Leu Phe Ala Glu Leu Ser Gly Asn Leu Val Pro Val Lys
                1295                1300                1305

 Lys Ala Ala Gln Gln Arg Ser Phe His Phe Gln Ser Phe Arg Glu
                1310                1315                1320

 Asn Arg Leu Ala Met Pro Val Lys Val Arg Asp Ser Ser Arg Glu
                1325                1330                1335

 Pro Gly Gly Ser Leu Ser Phe Leu Arg Lys Ala Met Lys Tyr Glu
                1340                1345                1350

 Asp Thr Gln His Ile Leu Cys His Leu Asn Ile Thr Met Pro Pro
                1355                1360                1365

 Cys Ala Lys Gly Ser Gly Ala Glu Asp Arg Arg Arg Thr Pro Thr
                1370                1375                1380

 Pro Leu Ala Leu Arg Tyr Ser Ile Leu Ser Glu Ser Thr Pro Gly
                1385                1390                1395

 Ser Leu Ser Gly Thr Glu Gln Ala Glu Met Lys Met Ala Val Ile
                1400                1405                1410

 Ser Glu His Leu Gly Leu Ser Trp Ala Glu Leu Ala Arg Glu Leu
                1415                1420                1425

 Gln Phe Ser Val Glu Asp Ile Asn Arg Ile Arg Val Glu Asn Pro
                1430                1435                1440

 Asn Ser Leu Leu Glu Gln Ser Val Ala Leu Leu Asn Leu Trp Val
                1445                1450                1455

 Ile Arg Glu Gly Gln Asn Ala Asn Met Glu Asn Leu Tyr Thr Ala
                1460                1465                1470

 Leu Gln Ser Ile Asp Arg Gly Glu Ile Val Asn Met Leu Glu Gly
                1475                1480                1485

 Ser Gly Arg Gln Ser Arg Asn Leu Lys Pro Asp Arg Arg His Thr
                1490                1495                1500

 Asp Arg Asp Tyr Ser Leu Ser Pro Ser Gln Met Asn Gly Tyr Ser
                1505                1510                1515

 Ser Leu Gln Asp Glu Leu Leu Ser Pro Ala Ser Leu Gly Cys Ala
                1520                1525                1530

 Leu Ser Ser Pro Leu Arg Ala Asp Gln Tyr Trp Asn Glu Val Ala
                1535                1540                1545

 Val Leu Asp Ala Ile Pro Leu Ala Ala Thr Glu His Asp Thr Met
                1550                1555                1560

 Leu Glu Met Ser Asp Met Gln Val Trp Ser Ala Gly Leu Thr Pro
                1565                1570                1575

 Ser Leu Val Thr Ala Glu Asp Ser Ser Leu Glu Cys Ser Lys Ala
                1580                1585                1590

 Glu Asp Ser Asp Ala Thr Gly His Glu Trp Lys Leu Glu Gly Ala
                1595                1600                1605

 Leu Ser Glu Glu Pro Arg Gly Pro Glu Leu Gly Ser Leu Glu Leu
                1610                1615                1620

 Val Glu Asp Asp Thr Val Asp Ser Asp Ala Thr Asn Gly Leu Ile
                1625                1630                1635

 Asp Leu Leu Glu Gln Glu Glu Gly Gln Arg Ser Glu Glu Lys Leu
                1640                1645                1650

 Pro Gly Ser Lys Arg Gln Asp Asp Ala Thr Gly Ala Gly Gln Asp
                1655                1660                1665

 Ser Glu Asn Glu Val Ser Leu Val Ser Gly His Gln Arg Gly Gln
                1670                1675                1680

 Ala Arg Ile Thr His Ser Pro Thr Val Ser Gln Val Thr Glu Arg
                1685                1690                1695

 Ser Gln Asp Arg Leu Gln Asp Trp Asp Ala Asp Gly Ser Ile Val
                1700                1705                1710

 Ser Tyr Leu Gln Asp Ala Ala Gln Gly Ser Trp Gln Glu Glu Val
                1715                1720                1725

 Thr Gln Gly Pro His Ser Phe Gln Gly Thr Ser Thr Met Thr Glu
                1730                1735                1740

 Gly Leu Glu Pro Gly Gly Ser Gln Glu Tyr Glu Lys Val Leu Val
                1745                1750                1755

 Ser Val Ser Glu His Thr Trp Thr Glu Gln Pro Glu Ala Glu Ser
                1760                1765                1770

 Ser Gln Ala Asp Arg Asp Arg Arg Gln Gln Gly Gln Glu Glu Gln
                1775                1780                1785

 Val Gln Glu Ala Lys Asn Thr Phe Thr Gln Val Val Gln Gly Asn
                1790                1795                1800

 Glu Phe Gln Asn Ile Pro Gly Glu Gln Val Thr Glu Glu Gln Phe
                1805                1810                1815

 Thr Asp Glu Gln Gly Asn Ile Val Thr Lys Lys Ile Ile Arg Lys
                1820                1825                1830

 Val Val Arg Gln Ile Asp Leu Ser Ser Ala Asp Ala Ala Gln Glu
                1835                1840                1845

 His Glu Glu Val Thr Val Glu Gly Pro Leu Glu Asp Pro Ser Glu
                1850                1855                1860

 Leu Glu Val Asp Ile Asp Tyr Phe Met Lys His Ser Lys Asp His
                1865                1870                1875

 Thr Ser Thr Pro Asn Pro
                1880

<210> 1343
<211> 2042
<212> DNA
<213> Homo sapien

<400> 1343
 ggggccagtc gttcgccgga aagcatttgt ctcccacctc atcataacaa 50

 caattaattt cctctggggc ctgaggaggg cagaatttca accttcggtg 100

 tgcttgggag tggcgattgt gatttacacg acaaaatgcc gaggtgctcg 150

 gtggagtcat ggcagtgccc tttgtggaag actgggactt ggtgcaaacc 200

 ctgggagaag gtgcctatgg agaagttcaa cttgctgtga atagagtaac 250

 tgaagaagca gtcgcagtga agattgtaga tatgaagcgt gccgtagact 300

 gtccagaaaa tattaagaaa gagatctgta tcaataaaat gctaaatcat 350

 gaaaatgtag taaaattcta tggtcacagg agagaaggca atatccaata 400

 tttatttctg gagtactgta gtggaggaga gctttttgac agaatagagc 450

 cagacatagg catgcctgaa ccagatgctc agagattctt ccatcaactc 500

 atggcagggg tggtttatct gcatggtatt ggaataactc acagggatat 550

 taaaccagaa aatcttctgt tggatgaaag ggataacctc aaaatctcag 600

 actttggctt ggcaacagta tttcggtata ataatcgtga gcgtttgttg 650

 aacaagatgt gtggtacttt accatatgtt gctccagaac ttctgaagag 700

 aagagaattt catgcagaac cagttgatgt ttggtcctgt ggaatagtac 750

 ttactgcaat gctcgctgga gaattgccat gggaccaacc cagtgacagc 800

 tgtcaggagt attctgactg gaaagaaaaa aaaacatacc tcaacccttg 850

 gaaaaaaatc gattctgctc ctctagctct gctgcataaa atcttagttg 900

 agaatccatc agcaagaatt accattccag acatcaaaaa agatagatgg 950

 tacaacaaac ccctcaagaa aggggcaaaa aggccccgag tcacttcagg 1000

 tggtgtgtca gagtctccca gtggattttc taagcacatt caatccaatt 1050

 tggacttctc tccagtaaac agtgcttcta gtgaagaaaa tgtgaagtac 1100

 tccagttctc agccagaacc ccgcacaggt ctttccttat gggataccag 1150

 cccctcatac attgataaat tggtacaagg gatcagcttt tcccagccca 1200

 catgtcctga tcatatgctt ttgaatagtc agttacttgg caccccagga 1250

 tcctcacaga acccctggca gcggttggtc aaaagaatga cacgattctt 1300

 taccaaattg gatgcagaca aatcttatca atgcctgaaa gagacttgtg 1350

 agaagttggg ctatcaatgg aagaaaagtt gtatgaatca ggttactata 1400

 tcaacaactg ataggagaaa caataaactc attttcaaag tgaatttgtt 1450

 agaaatggat gataaaatat tggttgactt ccggctttct aagggtgatg 1500

 gattggagtt caagagacac ttcctgaaga ttaaagggaa gctgattgat 1550

 attgtgagca gccagaaggt ttggcttcct gccacatgat cggaccatcg 1600

 gctctgggga atcctggtga atatagtgct gctatgttga cattattctt 1650

 cctagagaag attatcctgt cctgcaaact gcaaatagta gttcctgaag 1700

 tgttcacttc cctgtttatc caaacatctt ccaatttatt ttgtttgttc 1750

 ggcatacaaa taatacctat atcttaattg taagcaaaac tttggggaaa 1800

 ggatgaatag aattcatttg attatttctt catgtgtgtt tagtatctga 1850

 atttgaaact catctggtgg aaaccaagtt tcaggggaca tgagttttcc 1900

 agcttttata cacacgtatc tcatttttat caaaacattt tgtttaattc 1950

 aaaaagtaca tatttcttcc atgttgattt aattctaaga tgaaccaata 2000

 aagacataat tcttgcaaaa aaaaaaaaaa aaaaaaaaaa aa 2042

<210> 1344
<211> 476
<212> PRT
<213> Homo sapien

<400> 1344
 Met Ala Val Pro Phe Val Glu Asp Trp Asp Leu Val Gln Thr Leu
   1               5                  10                  15

 Gly Glu Gly Ala Tyr Gly Glu Val Gln Leu Ala Val Asn Arg Val
                  20                  25                  30

 Thr Glu Glu Ala Val Ala Val Lys Ile Val Asp Met Lys Arg Ala
                  35                  40                  45

 Val Asp Cys Pro Glu Asn Ile Lys Lys Glu Ile Cys Ile Asn Lys
                  50                  55                  60

 Met Leu Asn His Glu Asn Val Val Lys Phe Tyr Gly His Arg Arg
                  65                  70                  75

 Glu Gly Asn Ile Gln Tyr Leu Phe Leu Glu Tyr Cys Ser Gly Gly
                  80                  85                  90

 Glu Leu Phe Asp Arg Ile Glu Pro Asp Ile Gly Met Pro Glu Pro
                  95                 100                 105

 Asp Ala Gln Arg Phe Phe His Gln Leu Met Ala Gly Val Val Tyr
                 110                 115                 120

 Leu His Gly Ile Gly Ile Thr His Arg Asp Ile Lys Pro Glu Asn
                 125                 130                 135

 Leu Leu Leu Asp Glu Arg Asp Asn Leu Lys Ile Ser Asp Phe Gly
                 140                 145                 150

 Leu Ala Thr Val Phe Arg Tyr Asn Asn Arg Glu Arg Leu Leu Asn
                 155                 160                 165

 Lys Met Cys Gly Thr Leu Pro Tyr Val Ala Pro Glu Leu Leu Lys
                 170                 175                 180

 Arg Arg Glu Phe His Ala Glu Pro Val Asp Val Trp Ser Cys Gly
                 185                 190                 195

 Ile Val Leu Thr Ala Met Leu Ala Gly Glu Leu Pro Trp Asp Gln
                 200                 205                 210

 Pro Ser Asp Ser Cys Gln Glu Tyr Ser Asp Trp Lys Glu Lys Lys
                 215                 220                 225

 Thr Tyr Leu Asn Pro Trp Lys Lys Ile Asp Ser Ala Pro Leu Ala
                 230                 235                 240

 Leu Leu His Lys Ile Leu Val Glu Asn Pro Ser Ala Arg Ile Thr
                 245                 250                 255

 Ile Pro Asp Ile Lys Lys Asp Arg Trp Tyr Asn Lys Pro Leu Lys
                 260                 265                 270

 Lys Gly Ala Lys Arg Pro Arg Val Thr Ser Gly Gly Val Ser Glu
                 275                 280                 285

 Ser Pro Ser Gly Phe Ser Lys His Ile Gln Ser Asn Leu Asp Phe
                 290                 295                 300

 Ser Pro Val Asn Ser Ala Ser Ser Glu Glu Asn Val Lys Tyr Ser
                 305                 310                 315

 Ser Ser Gln Pro Glu Pro Arg Thr Gly Leu Ser Leu Trp Asp Thr
                 320                 325                 330

 Ser Pro Ser Tyr Ile Asp Lys Leu Val Gln Gly Ile Ser Phe Ser
                 335                 340                 345

 Gln Pro Thr Cys Pro Asp His Met Leu Leu Asn Ser Gln Leu Leu
                 350                 355                 360

 Gly Thr Pro Gly Ser Ser Gln Asn Pro Trp Gln Arg Leu Val Lys
                 365                 370                 375

 Arg Met Thr Arg Phe Phe Thr Lys Leu Asp Ala Asp Lys Ser Tyr
                 380                 385                 390

 Gln Cys Leu Lys Glu Thr Cys Glu Lys Leu Gly Tyr Gln Trp Lys
                 395                 400                 405

 Lys Ser Cys Met Asn Gln Val Thr Ile Ser Thr Thr Asp Arg Arg
                 410                 415                 420

 Asn Asn Lys Leu Ile Phe Lys Val Asn Leu Leu Glu Met Asp Asp
                 425                 430                 435

 Lys Ile Leu Val Asp Phe Arg Leu Ser Lys Gly Asp Gly Leu Glu
                 440                 445                 450

 Phe Lys Arg His Phe Leu Lys Ile Lys Gly Lys Leu Ile Asp Ile
                 455                 460                 465

 Val Ser Ser Gln Lys Val Trp Leu Pro Ala Thr
                 470                 475

<210> 1345
<211> 2042
<212> DNA
<213> Homo sapien

<400> 1345
 ggggccagtc gttcgccgga aagcatttgt ctcccacctc atcataacaa 50

 caattaattt cctctggggc ctgaggaggg cagaatttca accttcggtg 100

 tgcttgggag tggcgattgt gatttacacg acaaaatgcc gaggtgctcg 150

 gtggagtcat ggcagtgccc tttgtggaag actgggactt ggtgcaaacc 200

 ctgggagaag gtgcctatgg agaagttcaa cttgctgtga atagagtaac 250

 tgaagaagca gtcgcagtga agattgtaga tatgaagcgt gccgtagact 300

 gtccagaaaa tattaagaaa gagatctgta tcaataaaat gctaaatcat 350

 gaaaatgtag taaaattcta tggtcacagg agagaaggca atatccaata 400

 tttatttctg gagtactgta gtggaggaga gctttttgac agaatagagc 450

 cagacatagg catgcctgaa ccagatgctc agagattctt ccatcaactc 500

 atggcagggg tggtttatct gcatggtatt ggaataactc acagggatat 550

 taaaccagaa aatcttctgt tggatgaaag ggataacctc aaaatctcag 600

 actttggctt ggcaacagta tttcggtata ataatcgtga gcgtttgttg 650

 aacaagatgt gtggtacttt accatatgtt gctccagaac ttctgaagag 700

 aagagaattt catgcagaac cagttgatgt ttggtcctgt ggaatagtac 750

 ttactgcaat gctcgctgga gaattgccat gggaccaacc cagtgacagc 800

 tgtcaggagt attctgactg gaaagaaaaa aaaacatacc tcaacccttg 850

 gaaaaaaatc gattctgctc ctctagctct gctgcataaa atcttagttg 900

 agaatccatc agcaagaatt accattccag acatcaaaaa agatagatgg 950

 tacaacaaac ccctcaagaa aggggcaaaa aggccccgag tcacttcagg 1000

 tggtgtgtca gagtctccca gtggattttc taagcacatt caatccaatt 1050

 tggacttctc tccagtaaac agtgcttcta gtgaagaaaa tgtgaagtac 1100

 tccagttctc agccagaacc ccgcacaggt ctttccttat gggataccag 1150

 cccctcatac attgataaat tggtacaagg gatcagcttt tcccagccca 1200

 catgtcctga tcatatgctt ttgaatagtc agttacttgg caccccagga 1250

 tcctcacaga acccctggca gcggttggtc aaaagaatga cacgattctt 1300

 taccaaattg gatgcagaca aatcttatca atgcctgaaa gagacttgtg 1350

 agaagttggg ctatcaatgg aagaaaagtt gtatgaatca ggttactata 1400

 tcaacaactg ataggagaaa caataaactc attttcaaag tgaatttgtt 1450

 agaaatggat gataaaatat tggttgactt ccggctttct aagggtgatg 1500

 gattggagtt caagagacac ttcctgaaga ttaaagggaa gctgattgat 1550

 attgtgagca gccagaaggt ttggcttcct gccacatgat cggaccatcg 1600

 gctctgggga atcctggtga atatagtgct gctatgttga cattattctt 1650

 cctagagaag attatcctgt cctgcaaact gcaaatagta gttcctgaag 1700

 tgttcacttc cctgtttatc caaacatctt ccaatttatt ttgtttgttc 1750

 ggcatacaaa taatacctat atcttaattg taagcaaaac tttggggaaa 1800

 ggatgaatag aattcatttg attatttctt catgtgtgtt tagtatctga 1850

 atttgaaact catctggtgg aaaccaagtt tcaggggaca tgagttttcc 1900

 agcttttata cacacgtatc tcatttttat caaaacattt tgtttaattc 1950

 aaaaagtaca tatttcttcc atgttgattt aattctaaga tgaaccaata 2000

 aagacataat tcttgcaaaa aaaaaaaaaa aaaaaaaaaa aa 2042

<210> 1346
<211> 476
<212> PRT
<213> Homo sapien

<400> 1346
 Met Ala Val Pro Phe Val Glu Asp Trp Asp Leu Val Gln Thr Leu
   1               5                  10                  15

 Gly Glu Gly Ala Tyr Gly Glu Val Gln Leu Ala Val Asn Arg Val
                  20                  25                  30

 Thr Glu Glu Ala Val Ala Val Lys Ile Val Asp Met Lys Arg Ala
                  35                  40                  45

 Val Asp Cys Pro Glu Asn Ile Lys Lys Glu Ile Cys Ile Asn Lys
                  50                  55                  60

 Met Leu Asn His Glu Asn Val Val Lys Phe Tyr Gly His Arg Arg
                  65                  70                  75

 Glu Gly Asn Ile Gln Tyr Leu Phe Leu Glu Tyr Cys Ser Gly Gly
                  80                  85                  90

 Glu Leu Phe Asp Arg Ile Glu Pro Asp Ile Gly Met Pro Glu Pro
                  95                 100                 105

 Asp Ala Gln Arg Phe Phe His Gln Leu Met Ala Gly Val Val Tyr
                 110                 115                 120

 Leu His Gly Ile Gly Ile Thr His Arg Asp Ile Lys Pro Glu Asn
                 125                 130                 135

 Leu Leu Leu Asp Glu Arg Asp Asn Leu Lys Ile Ser Asp Phe Gly
                 140                 145                 150

 Leu Ala Thr Val Phe Arg Tyr Asn Asn Arg Glu Arg Leu Leu Asn
                 155                 160                 165

 Lys Met Cys Gly Thr Leu Pro Tyr Val Ala Pro Glu Leu Leu Lys
                 170                 175                 180

 Arg Arg Glu Phe His Ala Glu Pro Val Asp Val Trp Ser Cys Gly
                 185                 190                 195

 Ile Val Leu Thr Ala Met Leu Ala Gly Glu Leu Pro Trp Asp Gln
                 200                 205                 210

 Pro Ser Asp Ser Cys Gln Glu Tyr Ser Asp Trp Lys Glu Lys Lys
                 215                 220                 225

 Thr Tyr Leu Asn Pro Trp Lys Lys Ile Asp Ser Ala Pro Leu Ala
                 230                 235                 240

 Leu Leu His Lys Ile Leu Val Glu Asn Pro Ser Ala Arg Ile Thr
                 245                 250                 255

 Ile Pro Asp Ile Lys Lys Asp Arg Trp Tyr Asn Lys Pro Leu Lys
                 260                 265                 270

 Lys Gly Ala Lys Arg Pro Arg Val Thr Ser Gly Gly Val Ser Glu
                 275                 280                 285

 Ser Pro Ser Gly Phe Ser Lys His Ile Gln Ser Asn Leu Asp Phe
                 290                 295                 300

 Ser Pro Val Asn Ser Ala Ser Ser Glu Glu Asn Val Lys Tyr Ser
                 305                 310                 315

 Ser Ser Gln Pro Glu Pro Arg Thr Gly Leu Ser Leu Trp Asp Thr
                 320                 325                 330

 Ser Pro Ser Tyr Ile Asp Lys Leu Val Gln Gly Ile Ser Phe Ser
                 335                 340                 345

 Gln Pro Thr Cys Pro Asp His Met Leu Leu Asn Ser Gln Leu Leu
                 350                 355                 360

 Gly Thr Pro Gly Ser Ser Gln Asn Pro Trp Gln Arg Leu Val Lys
                 365                 370                 375

 Arg Met Thr Arg Phe Phe Thr Lys Leu Asp Ala Asp Lys Ser Tyr
                 380                 385                 390

 Gln Cys Leu Lys Glu Thr Cys Glu Lys Leu Gly Tyr Gln Trp Lys
                 395                 400                 405

 Lys Ser Cys Met Asn Gln Val Thr Ile Ser Thr Thr Asp Arg Arg
                 410                 415                 420

 Asn Asn Lys Leu Ile Phe Lys Val Asn Leu Leu Glu Met Asp Asp
                 425                 430                 435

 Lys Ile Leu Val Asp Phe Arg Leu Ser Lys Gly Asp Gly Leu Glu
                 440                 445                 450

 Phe Lys Arg His Phe Leu Lys Ile Lys Gly Lys Leu Ile Asp Ile
                 455                 460                 465

 Val Ser Ser Gln Lys Val Trp Leu Pro Ala Thr
                 470                 475

<210> 1347
<211> 2303
<212> DNA
<213> Homo sapien

<400> 1347
 cccggcgtcc cgtcgagccc agccccgccg ggggcgctcc tcgccgcccg 50

 cacgccctcc ccagccatgt cgtccatcct gcctttcact cccccgatcg 100

 tgaagcgcct gctgggctgg aagaagggcg agcagaacgg gcaggaggag 150

 aaatggtgcg agaaggcggt caagagcctg gtcaagaaac tcaagaagac 200

 ggggcagctg gacgagctgg agaaggccat caccacgcag aacgtcaaca 250

 ccaagtgcat caccatcccc aggtccctgg atggccggtt gcaggtgtcc 300

 catcggaagg ggctccctca tgtcatctac tgccgcctgt ggcgatggcc 350

 agacctgcac agccaccacg agctgcgggc catggagctg tgtgagttcg 400

 ccttcaatat gaagaaggac gaggtctgcg tgaatcccta ccactaccag 450

 agagtagaga caccagttct acctcctgtg ttggtgccac gccacacaga 500

 gatcccggcc gagttccccc cactggacga ctacagccat tccatccccg 550

 aaaacactaa cttccccgca ggcatcgagc cccagagcaa tattccagag 600

 accccacccc ctggctacct gagtgaagat ggagaaacca gtgaccacca 650

 gatgaaccac agcatggacg caggttctcc aaacctatcc ccgaatccga 700

 tgtccccagc acataataac ttggacctgc agccagttac ctactgcgag 750

 ccggccttct ggtgctccat ctcctactac gagctgaacc agcgcgtcgg 800

 ggagacattc cacgcctcgc agccatccat gactgtggat ggcttcaccg 850

 acccctccaa ttcggagcgc ttctgcctag ggctgctctc caatgtcaac 900

 aggaatgcag cagtggagct gacacggaga cacatcggaa gaggcgtgcg 950

 gctctactac atcggagggg aggtcttcgc agagtgcctc agtgacagcg 1000

 ctatttttgt ccagtctccc aactgtaacc agcgctatgg ctggcacccg 1050

 gccaccgtct gcaagatccc accaggatgc aacctgaaga tcttcaacaa 1100

 ccaggagttc gctgccctcc tggcccagtc ggtcaaccag ggctttgagg 1150

 ctgtctacca gttgacccga atgtgcacca tccgcatgag cttcgtcaaa 1200

 ggctggggag cggagtacag gagacagact gtgaccagta ccccctgctg 1250

 gattgagctg cacctgaatg ggcctttgca gtggcttgac aaggtcctca 1300

 cccagatggg ctccccaagc atccgctgtt ccagtgtgtc ttagagacat 1350

 caagtatggt aggggagggc aggcttgggg aaaatggcca tacaggaggt 1400

 ggagaaaatt ggaactctac tcaacccatt gttgtcaagg aagaagaaat 1450

 ctttctccct caactgaagg ggtgcaccca cctgttttct gaaacacacg 1500

 agcaaaccca gaggtggatg ttatgaacag ctgtgtctgc caaacacatt 1550

 taccctttgg ccccactttg aagggcaaga aatggcgtct gctctggtgg 1600

 cttaagtgag cagaacaggt agtattacac caccggcacc ctccccccag 1650

 actctttttt tgagtgacag ctttctggga tgtcacagtc caaccagaaa 1700

 cgcccctctg tctaggactg cagtgtggag ttcaccttgg aagggcgttc 1750

 taggtaggaa gagcccgcac gatgcagacc tcatgcccag ctctctgacg 1800

 cttgtgacag tgcctcttcc agtgaacatt cccagcccag ccccgccccg 1850

 ttgtgagctg gatagacttg ggatggggag ggagggagtt ttgtctgtct 1900

 ccctcccctc tcagaacata ctgattggga ggtgcgtgtt cagcagaacc 1950

 tgcacacagg acagcgggaa aaatcgatga gcgccacctc tttaaaaact 2000

 cacttacgtt gtcctttttc actttgaaaa gttggaagga ctgctgaggc 2050

 ccagtgcata tgcaatgtat agtgtctatt atcacattaa tctcaaagag 2100

 attcgaatga cggtaagtgt tctcatgaag caggaggccc ttgtcgtggg 2150

 atggcatttg gtctcaggca gcaccacact gggtgcgtct ccagtcatct 2200

 gtaagagctt gctccagatt ctgatgcata cggctatatt ggtttatgta 2250

 gtcagttgca ttcattaaat caactttatc atatgctcaa aaaaaaaaaa 2300

 aag 2303

<210> 1348
<211> 425
<212> PRT
<213> Homo sapien

<400> 1348
 Met Ser Ser Ile Leu Pro Phe Thr Pro Pro Ile Val Lys Arg Leu
   1               5                  10                  15

 Leu Gly Trp Lys Lys Gly Glu Gln Asn Gly Gln Glu Glu Lys Trp
                  20                  25                  30

 Cys Glu Lys Ala Val Lys Ser Leu Val Lys Lys Leu Lys Lys Thr
                  35                  40                  45

 Gly Gln Leu Asp Glu Leu Glu Lys Ala Ile Thr Thr Gln Asn Val
                  50                  55                  60

 Asn Thr Lys Cys Ile Thr Ile Pro Arg Ser Leu Asp Gly Arg Leu
                  65                  70                  75

 Gln Val Ser His Arg Lys Gly Leu Pro His Val Ile Tyr Cys Arg
                  80                  85                  90

 Leu Trp Arg Trp Pro Asp Leu His Ser His His Glu Leu Arg Ala
                  95                 100                 105

 Met Glu Leu Cys Glu Phe Ala Phe Asn Met Lys Lys Asp Glu Val
                 110                 115                 120

 Cys Val Asn Pro Tyr His Tyr Gln Arg Val Glu Thr Pro Val Leu
                 125                 130                 135

 Pro Pro Val Leu Val Pro Arg His Thr Glu Ile Pro Ala Glu Phe
                 140                 145                 150

 Pro Pro Leu Asp Asp Tyr Ser His Ser Ile Pro Glu Asn Thr Asn
                 155                 160                 165

 Phe Pro Ala Gly Ile Glu Pro Gln Ser Asn Ile Pro Glu Thr Pro
                 170                 175                 180

 Pro Pro Gly Tyr Leu Ser Glu Asp Gly Glu Thr Ser Asp His Gln
                 185                 190                 195

 Met Asn His Ser Met Asp Ala Gly Ser Pro Asn Leu Ser Pro Asn
                 200                 205                 210

 Pro Met Ser Pro Ala His Asn Asn Leu Asp Leu Gln Pro Val Thr
                 215                 220                 225

 Tyr Cys Glu Pro Ala Phe Trp Cys Ser Ile Ser Tyr Tyr Glu Leu
                 230                 235                 240

 Asn Gln Arg Val Gly Glu Thr Phe His Ala Ser Gln Pro Ser Met
                 245                 250                 255

 Thr Val Asp Gly Phe Thr Asp Pro Ser Asn Ser Glu Arg Phe Cys
                 260                 265                 270

 Leu Gly Leu Leu Ser Asn Val Asn Arg Asn Ala Ala Val Glu Leu
                 275                 280                 285

 Thr Arg Arg His Ile Gly Arg Gly Val Arg Leu Tyr Tyr Ile Gly
                 290                 295                 300

 Gly Glu Val Phe Ala Glu Cys Leu Ser Asp Ser Ala Ile Phe Val
                 305                 310                 315

 Gln Ser Pro Asn Cys Asn Gln Arg Tyr Gly Trp His Pro Ala Thr
                 320                 325                 330

 Val Cys Lys Ile Pro Pro Gly Cys Asn Leu Lys Ile Phe Asn Asn
                 335                 340                 345

 Gln Glu Phe Ala Ala Leu Leu Ala Gln Ser Val Asn Gln Gly Phe
                 350                 355                 360

 Glu Ala Val Tyr Gln Leu Thr Arg Met Cys Thr Ile Arg Met Ser
                 365                 370                 375

 Phe Val Lys Gly Trp Gly Ala Glu Tyr Arg Arg Gln Thr Val Thr
                 380                 385                 390

 Ser Thr Pro Cys Trp Ile Glu Leu His Leu Asn Gly Pro Leu Gln
                 395                 400                 405

 Trp Leu Asp Lys Val Leu Thr Gln Met Gly Ser Pro Ser Ile Arg
                 410                 415                 420

 Cys Ser Ser Val Ser
                 425

<210> 1349
<211> 2303
<212> DNA
<213> Homo sapien

<400> 1349
 cccggcgtcc cgtcgagccc agccccgccg ggggcgctcc tcgccgcccg 50

 cacgccctcc ccagccatgt cgtccatcct gcctttcact cccccgatcg 100

 tgaagcgcct gctgggctgg aagaagggcg agcagaacgg gcaggaggag 150

 aaatggtgcg agaaggcggt caagagcctg gtcaagaaac tcaagaagac 200

 ggggcagctg gacgagctgg agaaggccat caccacgcag aacgtcaaca 250

 ccaagtgcat caccatcccc aggtccctgg atggccggtt gcaggtgtcc 300

 catcggaagg ggctccctca tgtcatctac tgccgcctgt ggcgatggcc 350

 agacctgcac agccaccacg agctgcgggc catggagctg tgtgagttcg 400

 ccttcaatat gaagaaggac gaggtctgcg tgaatcccta ccactaccag 450

 agagtagaga caccagttct acctcctgtg ttggtgccac gccacacaga 500

 gatcccggcc gagttccccc cactggacga ctacagccat tccatccccg 550

 aaaacactaa cttccccgca ggcatcgagc cccagagcaa tattccagag 600

 accccacccc ctggctacct gagtgaagat ggagaaacca gtgaccacca 650

 gatgaaccac agcatggacg caggttctcc aaacctatcc ccgaatccga 700

 tgtccccagc acataataac ttggacctgc agccagttac ctactgcgag 750

 ccggccttct ggtgctccat ctcctactac gagctgaacc agcgcgtcgg 800

 ggagacattc cacgcctcgc agccatccat gactgtggat ggcttcaccg 850

 acccctccaa ttcggagcgc ttctgcctag ggctgctctc caatgtcaac 900

 aggaatgcag cagtggagct gacacggaga cacatcggaa gaggcgtgcg 950

 gctctactac atcggagggg aggtcttcgc agagtgcctc agtgacagcg 1000

 ctatttttgt ccagtctccc aactgtaacc agcgctatgg ctggcacccg 1050

 gccaccgtct gcaagatccc accaggatgc aacctgaaga tcttcaacaa 1100

 ccaggagttc gctgccctcc tggcccagtc ggtcaaccag ggctttgagg 1150

 ctgtctacca gttgacccga atgtgcacca tccgcatgag cttcgtcaaa 1200

 ggctggggag cggagtacag gagacagact gtgaccagta ccccctgctg 1250

 gattgagctg cacctgaatg ggcctttgca gtggcttgac aaggtcctca 1300

 cccagatggg ctccccaagc atccgctgtt ccagtgtgtc ttagagacat 1350

 caagtatggt aggggagggc aggcttgggg aaaatggcca tacaggaggt 1400

 ggagaaaatt ggaactctac tcaacccatt gttgtcaagg aagaagaaat 1450

 ctttctccct caactgaagg ggtgcaccca cctgttttct gaaacacacg 1500

 agcaaaccca gaggtggatg ttatgaacag ctgtgtctgc caaacacatt 1550

 taccctttgg ccccactttg aagggcaaga aatggcgtct gctctggtgg 1600

 cttaagtgag cagaacaggt agtattacac caccggcacc ctccccccag 1650

 actctttttt tgagtgacag ctttctggga tgtcacagtc caaccagaaa 1700

 cgcccctctg tctaggactg cagtgtggag ttcaccttgg aagggcgttc 1750

 taggtaggaa gagcccgcac gatgcagacc tcatgcccag ctctctgacg 1800

 cttgtgacag tgcctcttcc agtgaacatt cccagcccag ccccgccccg 1850

 ttgtgagctg gatagacttg ggatggggag ggagggagtt ttgtctgtct 1900

 ccctcccctc tcagaacata ctgattggga ggtgcgtgtt cagcagaacc 1950

 tgcacacagg acagcgggaa aaatcgatga gcgccacctc tttaaaaact 2000

 cacttacgtt gtcctttttc actttgaaaa gttggaagga ctgctgaggc 2050

 ccagtgcata tgcaatgtat agtgtctatt atcacattaa tctcaaagag 2100

 attcgaatga cggtaagtgt tctcatgaag caggaggccc ttgtcgtggg 2150

 atggcatttg gtctcaggca gcaccacact gggtgcgtct ccagtcatct 2200

 gtaagagctt gctccagatt ctgatgcata cggctatatt ggtttatgta 2250

 gtcagttgca ttcattaaat caactttatc atatgctcaa aaaaaaaaaa 2300

 aag 2303

<210> 1350
<211> 425
<212> PRT
<213> Homo sapien

<400> 1350
 Met Ser Ser Ile Leu Pro Phe Thr Pro Pro Ile Val Lys Arg Leu
   1               5                  10                  15

 Leu Gly Trp Lys Lys Gly Glu Gln Asn Gly Gln Glu Glu Lys Trp
                  20                  25                  30

 Cys Glu Lys Ala Val Lys Ser Leu Val Lys Lys Leu Lys Lys Thr
                  35                  40                  45

 Gly Gln Leu Asp Glu Leu Glu Lys Ala Ile Thr Thr Gln Asn Val
                  50                  55                  60

 Asn Thr Lys Cys Ile Thr Ile Pro Arg Ser Leu Asp Gly Arg Leu
                  65                  70                  75

 Gln Val Ser His Arg Lys Gly Leu Pro His Val Ile Tyr Cys Arg
                  80                  85                  90

 Leu Trp Arg Trp Pro Asp Leu His Ser His His Glu Leu Arg Ala
                  95                 100                 105

 Met Glu Leu Cys Glu Phe Ala Phe Asn Met Lys Lys Asp Glu Val
                 110                 115                 120

 Cys Val Asn Pro Tyr His Tyr Gln Arg Val Glu Thr Pro Val Leu
                 125                 130                 135

 Pro Pro Val Leu Val Pro Arg His Thr Glu Ile Pro Ala Glu Phe
                 140                 145                 150

 Pro Pro Leu Asp Asp Tyr Ser His Ser Ile Pro Glu Asn Thr Asn
                 155                 160                 165

 Phe Pro Ala Gly Ile Glu Pro Gln Ser Asn Ile Pro Glu Thr Pro
                 170                 175                 180

 Pro Pro Gly Tyr Leu Ser Glu Asp Gly Glu Thr Ser Asp His Gln
                 185                 190                 195

 Met Asn His Ser Met Asp Ala Gly Ser Pro Asn Leu Ser Pro Asn
                 200                 205                 210

 Pro Met Ser Pro Ala His Asn Asn Leu Asp Leu Gln Pro Val Thr
                 215                 220                 225

 Tyr Cys Glu Pro Ala Phe Trp Cys Ser Ile Ser Tyr Tyr Glu Leu
                 230                 235                 240

 Asn Gln Arg Val Gly Glu Thr Phe His Ala Ser Gln Pro Ser Met
                 245                 250                 255

 Thr Val Asp Gly Phe Thr Asp Pro Ser Asn Ser Glu Arg Phe Cys
                 260                 265                 270

 Leu Gly Leu Leu Ser Asn Val Asn Arg Asn Ala Ala Val Glu Leu
                 275                 280                 285

 Thr Arg Arg His Ile Gly Arg Gly Val Arg Leu Tyr Tyr Ile Gly
                 290                 295                 300

 Gly Glu Val Phe Ala Glu Cys Leu Ser Asp Ser Ala Ile Phe Val
                 305                 310                 315

 Gln Ser Pro Asn Cys Asn Gln Arg Tyr Gly Trp His Pro Ala Thr
                 320                 325                 330

 Val Cys Lys Ile Pro Pro Gly Cys Asn Leu Lys Ile Phe Asn Asn
                 335                 340                 345

 Gln Glu Phe Ala Ala Leu Leu Ala Gln Ser Val Asn Gln Gly Phe
                 350                 355                 360

 Glu Ala Val Tyr Gln Leu Thr Arg Met Cys Thr Ile Arg Met Ser
                 365                 370                 375

 Phe Val Lys Gly Trp Gly Ala Glu Tyr Arg Arg Gln Thr Val Thr
                 380                 385                 390

 Ser Thr Pro Cys Trp Ile Glu Leu His Leu Asn Gly Pro Leu Gln
                 395                 400                 405

 Trp Leu Asp Lys Val Leu Thr Gln Met Gly Ser Pro Ser Ile Arg
                 410                 415                 420

 Cys Ser Ser Val Ser
                 425

<210> 1351
<211> 1638
<212> DNA
<213> Homo sapien

<400> 1351
 ggaattccct gatatacacc tggaccacca ccaatggata tacaaatggc 50

 aaacaatttt actccgccct ctgcaactcc tcagggaaat gactgtgacc 100

 tctatgcaca tcacagcacg gccaggatag taatgcctct gcattacagc 150

 ctcgtcttca tcattgggct cgtgggaaac ttactagcct tggtcgtcat 200

 tgttcaaaac aggaaaaaaa tcaactctac caccctctat tcaacaaatt 250

 tggtgatttc tgatatactt tttaccaccg ctttgcctac acgaatagcc 300

 tactatgcaa tgggctttga ctggagaatc ggagatgcct tgtgtaggat 350

 aactgcgcta gtgttttaca tcaacacata tgcaggtgtg aactttatga 400

 cctgcctgag tattgaccgc ttcattgctg tggtgcaccc tctacgctac 450

 aacaagataa aaaggattga acatgcaaaa ggcgtgtgca tatttgtctg 500

 gattctagta tttgctcaga cactcccact cctcatcaac cctatgtcaa 550

 agcaggaggc tgaaaggatt acatgcatgg agtatccaaa ctttgaagaa 600

 actaaatctc ttccctggat tctgcttggg gcatgtttca taggatatgt 650

 acttccactt ataatcattc tcatctgcta ttctcagatc tgctgcaaac 700

 tcttcagaac tgccaaacaa aacccactca ctgagaaatc tggtgtaaac 750

 aaaaaggctc tcaacacaat tattcttatt attgttgtgt ttgttctctg 800

 tttcacacct taccatgttg caattattca acatatgatt aagaagcttc 850

 gtttctctaa tttcctggaa tgtagccaaa gacattcgtt ccagatttct 900

 ctgcacttta cagtatgcct gatgaacttc aattgctgca tggacccttt 950

 tatctacttc tttgcatgta aagggtataa gagaaaggtt atgaggatgc 1000

 tgaaacggca agtcagtgta tcgatttcta gtgctgtgaa gtcagcccct 1050

 gaagaaaatt cacgtgaaat gacagaaacg cagatgatga tacattccaa 1100

 gtcttcaaat ggaaagtgaa atggattgta ttttggttta tagtgacgta 1150

 aactgtatga caaactttgc aggacttccc ttataaagca aaataattgt 1200

 tcagcttcca attagtattc ttttatattt ctttcattgg gcactttccc 1250

 atctccaact cggaagtaag cccaagagaa caacataaag caaacaacat 1300

 aaagcacaat aaaaatgcaa ataaatattt tcatttttat ttgtaaacga 1350

 atacaccaaa aggaggcgct cttaataact cccaatgtaa aaagttttgt 1400

 tttaataaaa aatttaatta ttatttcttg ccaacaaatg gctagaaagg 1450

 actgaataga ttatatattg ccagatgtta atactgtaac atacttttta 1500

 aataacatat ttcttaaatc caaatttctc tcaatgttag atttaattcc 1550

 ctcaataaca ccaatgtttt gttttgtttc gttctgggtc ataaaacttt 1600

 gttaaggaac tcttttggaa taaagagcag gatgctgc 1638

<210> 1352
<211> 361
<212> PRT
<213> Homo sapien

<400> 1352
 Met Asp Ile Gln Met Ala Asn Asn Phe Thr Pro Pro Ser Ala Thr
   1               5                  10                  15

 Pro Gln Gly Asn Asp Cys Asp Leu Tyr Ala His His Ser Thr Ala
                  20                  25                  30

 Arg Ile Val Met Pro Leu His Tyr Ser Leu Val Phe Ile Ile Gly
                  35                  40                  45

 Leu Val Gly Asn Leu Leu Ala Leu Val Val Ile Val Gln Asn Arg
                  50                  55                  60

 Lys Lys Ile Asn Ser Thr Thr Leu Tyr Ser Thr Asn Leu Val Ile
                  65                  70                  75

 Ser Asp Ile Leu Phe Thr Thr Ala Leu Pro Thr Arg Ile Ala Tyr
                  80                  85                  90

 Tyr Ala Met Gly Phe Asp Trp Arg Ile Gly Asp Ala Leu Cys Arg
                  95                 100                 105

 Ile Thr Ala Leu Val Phe Tyr Ile Asn Thr Tyr Ala Gly Val Asn
                 110                 115                 120

 Phe Met Thr Cys Leu Ser Ile Asp Arg Phe Ile Ala Val Val His
                 125                 130                 135

 Pro Leu Arg Tyr Asn Lys Ile Lys Arg Ile Glu His Ala Lys Gly
                 140                 145                 150

 Val Cys Ile Phe Val Trp Ile Leu Val Phe Ala Gln Thr Leu Pro
                 155                 160                 165

 Leu Leu Ile Asn Pro Met Ser Lys Gln Glu Ala Glu Arg Ile Thr
                 170                 175                 180

 Cys Met Glu Tyr Pro Asn Phe Glu Glu Thr Lys Ser Leu Pro Trp
                 185                 190                 195

 Ile Leu Leu Gly Ala Cys Phe Ile Gly Tyr Val Leu Pro Leu Ile
                 200                 205                 210

 Ile Ile Leu Ile Cys Tyr Ser Gln Ile Cys Cys Lys Leu Phe Arg
                 215                 220                 225

 Thr Ala Lys Gln Asn Pro Leu Thr Glu Lys Ser Gly Val Asn Lys
                 230                 235                 240

 Lys Ala Leu Asn Thr Ile Ile Leu Ile Ile Val Val Phe Val Leu
                 245                 250                 255

 Cys Phe Thr Pro Tyr His Val Ala Ile Ile Gln His Met Ile Lys
                 260                 265                 270

 Lys Leu Arg Phe Ser Asn Phe Leu Glu Cys Ser Gln Arg His Ser
                 275                 280                 285

 Phe Gln Ile Ser Leu His Phe Thr Val Cys Leu Met Asn Phe Asn
                 290                 295                 300

 Cys Cys Met Asp Pro Phe Ile Tyr Phe Phe Ala Cys Lys Gly Tyr
                 305                 310                 315

 Lys Arg Lys Val Met Arg Met Leu Lys Arg Gln Val Ser Val Ser
                 320                 325                 330

 Ile Ser Ser Ala Val Lys Ser Ala Pro Glu Glu Asn Ser Arg Glu
                 335                 340                 345

 Met Thr Glu Thr Gln Met Met Ile His Ser Lys Ser Ser Asn Gly
                 350                 355                 360

 Lys


<210> 1353
<211> 2201
<212> DNA
<213> Homo sapien

<400> 1353
 caactacgag ccacgagttt gcagatgggg ctgctcggcg gcgcctgtgg 50

 ctgagggaga gcagcggcgg cggggagcga ccgggagcgg cggcagcggc 100

 ggcgcggagg cggctgaggt gcgagccgga ctaaatcatt ttgctacttt 150

 aaaaaaatca cgaaagtaca ttatttgaag tttggagaag aaagggattt 200

 ggtaacaaag gacagccatt tccattttaa gcagctaaac agcaggagag 250

 atttctgtaa gaaggtacca gctcagattc cattgttcat cattttgcaa 300

 tgcagcaagt cttggaaaac cttacggagc tgccctcgtc tactggagca 350

 gaagaaatag acctaatttt cctcaaggga attatggaga atcctattgt 400

 aaaatcactt gctaaggctc atgagaggct agaagattcc aaactagaag 450

 ctgtcagtga caataacttg gaattagtca atgaaattct tgaagacatc 500

 actcctctaa taaatgtgga tgaaaatgtg gcagaattgg ttggtatact 550

 caaagaacct cacttccagt cactgttgga ggcccatgat attgtggcat 600

 caaagtgtta tgattcacct ccatcaagcc cagaaatgaa taattcttct 650

 atcaataatc agttattacc agtagatgcc attcgtattc ttggtattca 700

 caaaagagct ggggaaccac tgggtgtgac atttagggtt gaaaataatg 750

 atctggtaat tgcccgaatc ctccatgggg gaatgataga tcgacaaggt 800

 ctacttcatg tgggagatat aattaaagaa gtcaatggcc atgaggttgg 850

 aaataatcca aaggaattac aagaattact gaaaaatatt agtggaagtg 900

 tcaccctaaa aatcttacca agttatagag ataccattac tcctcaacag 950

 gtatttgtga agtgtcattt tgattataat ccatacaatg acaacctaat 1000

 accttgcaaa gaagcaggat tgaagttttc caaaggagaa attcttcaga 1050

 ttgtaaatag agaagatcca aattggtggc aggctagcca tgtaaaagag 1100

 ggaggaagcg ctggtctcat tccaagccag ttcctggaag agaagagaaa 1150

 ggcatttgtt agaagagact gggacaattc aggacctttt tgtggaacta 1200

 taagtagcaa aaaaaagaaa aagatgatgt atctcacaac cagaaatgca 1250

 gaatttgatc gtcatgaaat ccagatatat gaggaggtag ccaaaatgcc 1300

 tcccttccag agaaaaacat tagtattgat aggagctcaa ggtgtaggcc 1350

 gaagaagctt gaaaaacagg ttcatagtat tgaatcccac tagatttgga 1400

 actacggtgc catttacttc acggaaacca agggaagatg aaaaagatgg 1450

 ccaggcatat aagtttgtgt cacgatctga gatggaagca gatattaaag 1500

 ctggaaagta tttggaacat ggggaatatg aaggaaatct ctatggaacc 1550

 aaaattgatt ctattcttga ggttgtccaa actggacgga cttgcattct 1600

 ggatgtcaac ccacaagcac tgaaagtatt gaggacatca gagtttatgc 1650

 cctatgtggt atttattgcg gctccggagc tagagacgtt acgtgccatg 1700

 cacaaggctg tggtggatgc aggaatcact accaagcttc tgaccgactc 1750

 tgacttgaag aaaacagtgg atgaaagtgc acggattcag agagcataca 1800

 accactattt tgatttgatc atcataaatg ataatctaga caaagccttt 1850

 gaaaaactgc aaactgccat agagaaactg agaatggaac cacagtgggt 1900

 cccaatcagc tgggtttact gatgattcag taaggttaac aatgaaaatt 1950

 aaactcttaa aaagtgactg caacaaataa accttctact gagaaaatac 2000

 atcacagata gaagattatc tgctaagtcc aggcattttt atggtgtaga 2050

 ttgaaataat agtacacttc tgaattttta tataaaatgt ggttggaagg 2100

 tgtactaata tataatttat cttaattttt ctaactttgt atggataatc 2150

 tttctattca tatcacataa agaaatgcgt tgaagcaaaa aaaaaaaaaa 2200

 a 2201

<210> 1354
<211> 540
<212> PRT
<213> Homo sapien

<400> 1354
 Met Gln Gln Val Leu Glu Asn Leu Thr Glu Leu Pro Ser Ser Thr
   1               5                  10                  15

 Gly Ala Glu Glu Ile Asp Leu Ile Phe Leu Lys Gly Ile Met Glu
                  20                  25                  30

 Asn Pro Ile Val Lys Ser Leu Ala Lys Ala His Glu Arg Leu Glu
                  35                  40                  45

 Asp Ser Lys Leu Glu Ala Val Ser Asp Asn Asn Leu Glu Leu Val
                  50                  55                  60

 Asn Glu Ile Leu Glu Asp Ile Thr Pro Leu Ile Asn Val Asp Glu
                  65                  70                  75

 Asn Val Ala Glu Leu Val Gly Ile Leu Lys Glu Pro His Phe Gln
                  80                  85                  90

 Ser Leu Leu Glu Ala His Asp Ile Val Ala Ser Lys Cys Tyr Asp
                  95                 100                 105

 Ser Pro Pro Ser Ser Pro Glu Met Asn Asn Ser Ser Ile Asn Asn
                 110                 115                 120

 Gln Leu Leu Pro Val Asp Ala Ile Arg Ile Leu Gly Ile His Lys
                 125                 130                 135

 Arg Ala Gly Glu Pro Leu Gly Val Thr Phe Arg Val Glu Asn Asn
                 140                 145                 150

 Asp Leu Val Ile Ala Arg Ile Leu His Gly Gly Met Ile Asp Arg
                 155                 160                 165

 Gln Gly Leu Leu His Val Gly Asp Ile Ile Lys Glu Val Asn Gly
                 170                 175                 180

 His Glu Val Gly Asn Asn Pro Lys Glu Leu Gln Glu Leu Leu Lys
                 185                 190                 195

 Asn Ile Ser Gly Ser Val Thr Leu Lys Ile Leu Pro Ser Tyr Arg
                 200                 205                 210

 Asp Thr Ile Thr Pro Gln Gln Val Phe Val Lys Cys His Phe Asp
                 215                 220                 225

 Tyr Asn Pro Tyr Asn Asp Asn Leu Ile Pro Cys Lys Glu Ala Gly
                 230                 235                 240

 Leu Lys Phe Ser Lys Gly Glu Ile Leu Gln Ile Val Asn Arg Glu
                 245                 250                 255

 Asp Pro Asn Trp Trp Gln Ala Ser His Val Lys Glu Gly Gly Ser
                 260                 265                 270

 Ala Gly Leu Ile Pro Ser Gln Phe Leu Glu Glu Lys Arg Lys Ala
                 275                 280                 285

 Phe Val Arg Arg Asp Trp Asp Asn Ser Gly Pro Phe Cys Gly Thr
                 290                 295                 300

 Ile Ser Ser Lys Lys Lys Lys Lys Met Met Tyr Leu Thr Thr Arg
                 305                 310                 315

 Asn Ala Glu Phe Asp Arg His Glu Ile Gln Ile Tyr Glu Glu Val
                 320                 325                 330

 Ala Lys Met Pro Pro Phe Gln Arg Lys Thr Leu Val Leu Ile Gly
                 335                 340                 345

 Ala Gln Gly Val Gly Arg Arg Ser Leu Lys Asn Arg Phe Ile Val
                 350                 355                 360

 Leu Asn Pro Thr Arg Phe Gly Thr Thr Val Pro Phe Thr Ser Arg
                 365                 370                 375

 Lys Pro Arg Glu Asp Glu Lys Asp Gly Gln Ala Tyr Lys Phe Val
                 380                 385                 390

 Ser Arg Ser Glu Met Glu Ala Asp Ile Lys Ala Gly Lys Tyr Leu
                 395                 400                 405

 Glu His Gly Glu Tyr Glu Gly Asn Leu Tyr Gly Thr Lys Ile Asp
                 410                 415                 420

 Ser Ile Leu Glu Val Val Gln Thr Gly Arg Thr Cys Ile Leu Asp
                 425                 430                 435

 Val Asn Pro Gln Ala Leu Lys Val Leu Arg Thr Ser Glu Phe Met
                 440                 445                 450

 Pro Tyr Val Val Phe Ile Ala Ala Pro Glu Leu Glu Thr Leu Arg
                 455                 460                 465

 Ala Met His Lys Ala Val Val Asp Ala Gly Ile Thr Thr Lys Leu
                 470                 475                 480

 Leu Thr Asp Ser Asp Leu Lys Lys Thr Val Asp Glu Ser Ala Arg
                 485                 490                 495

 Ile Gln Arg Ala Tyr Asn His Tyr Phe Asp Leu Ile Ile Ile Asn
                 500                 505                 510

 Asp Asn Leu Asp Lys Ala Phe Glu Lys Leu Gln Thr Ala Ile Glu
                 515                 520                 525

 Lys Leu Arg Met Glu Pro Gln Trp Val Pro Ile Ser Trp Val Tyr
                 530                 535                 540

<210> 1355
<211> 1585
<212> DNA
<213> Homo sapien

<400> 1355
 acagcagtta cactgcggcg ggcgtctgtt ctagtgtttg agccgtcgtg 50

 cttcaccggt ctacctcgct agcatgtcgg gccgcggcaa gactggcggc 100

 aaggcccgcg ccaaggccaa gtcgcgctcg tcgcgcgccg gcctccagtt 150

 cccagtgggc cgtgtacacc ggctgctgcg gaagggccac tacgccgagc 200

 gcgttggcgc cggcgcgcca gtgtacctgg cggcagtgct ggagtacctc 250

 accgctgaga tcctggagct ggcgggcaat gcggcccgcg acaacaagaa 300

 gacgcgaatc atcccccgcc acctgcagct ggccatccgc aacgacgagg 350

 agctcaacaa gctgctgggc ggcgtgacga tcgcccaggg aggcgtcctg 400

 cccaacatcc aggccgtgct gctgcccaag aagaccagcg ccaccgtggg 450

 gccgaaggcg ccctcgggcg gcaagaaggc cacccaggcc tcccaggagt 500

 actaagaggg cccgcgccgc ggccggccgc cccagctccc catgccacca 550

 caaaggccct tttaagggcc accaccgccc tcatggaaag agctgagccg 600

 cttcagactg cggggcaagc gggccgcggc tcccttcccc tcccctcccc 650

 tcgcccgcct tcgccgcccg gcctcgagtc cccgcccgcc cccgctcccg 700

 tcccgcaccg cctgccgcgt cggcctcggg cctgccctgt ccgccgtccg 750

 ccctccggta gggttcgggc cttccggatg cggcttgggc gctcttcggg 800

 gacctccgtg gcgcggaaga cccgagcctg ccggggggag gccggcggcg 850

 ccgcacctgc ccgcctcggc gttcgtgact cagccgcccc atcccgagtc 900

 gctaaggggc tgcggggagg ccgcagcacc ttctggaaga cttggccttc 950

 cgctctgacg cagggccgag gtgggcagtc caggccgaga gccggcggcc 1000

 ctgaaggtga gtgaggccct cggcagctgc agccggggtg tctggtaccc 1050

 ccccggcgtg gtgcttagcc caggactttc agacggccgc tggccgggag 1100

 gctttggtgg gagagacgcg atcgccgatt tcggtctggc gccccttctg 1150

 cggccgggac ccaggccttt cacatcagct ctccctccat cttcattcat 1200

 aggtctgcgc tggggccggg acgaagcact tggtaacagg cacatcttcc 1250

 tcccgagtga ctgcctccta ggaggacatt taggggaggg cagaggcctg 1300

 cagtttggct tcacggctgg ctatgtggac agcaagagtc gttttgcgga 1350

 acgcgactgg cagccaggcc tgtcgggccc ccgacgccgc cccatttccc 1400

 ttccagcaaa ctcaactcgg caatccaagc acctagatac cagcacaagt 1450

 cggttaatcc ctgtctggac tgagcctccg ttggcttctg aactggaatt 1500

 ctgcagctaa cccttccacg actagaacct taggcattgg ggagttttag 1550

 atggactaat tttattaaag gattgttttt ttttt 1585

<210> 1356
<211> 143
<212> PRT
<213> Homo sapien

<400> 1356
 Met Ser Gly Arg Gly Lys Thr Gly Gly Lys Ala Arg Ala Lys Ala
   1               5                  10                  15

 Lys Ser Arg Ser Ser Arg Ala Gly Leu Gln Phe Pro Val Gly Arg
                  20                  25                  30

 Val His Arg Leu Leu Arg Lys Gly His Tyr Ala Glu Arg Val Gly
                  35                  40                  45

 Ala Gly Ala Pro Val Tyr Leu Ala Ala Val Leu Glu Tyr Leu Thr
                  50                  55                  60

 Ala Glu Ile Leu Glu Leu Ala Gly Asn Ala Ala Arg Asp Asn Lys
                  65                  70                  75

 Lys Thr Arg Ile Ile Pro Arg His Leu Gln Leu Ala Ile Arg Asn
                  80                  85                  90

 Asp Glu Glu Leu Asn Lys Leu Leu Gly Gly Val Thr Ile Ala Gln
                  95                 100                 105

 Gly Gly Val Leu Pro Asn Ile Gln Ala Val Leu Leu Pro Lys Lys
                 110                 115                 120

 Thr Ser Ala Thr Val Gly Pro Lys Ala Pro Ser Gly Gly Lys Lys
                 125                 130                 135

 Ala Thr Gln Ala Ser Gln Glu Tyr
                 140

<210> 1357
<211> 1579
<212> DNA
<213> Homo sapien

<400> 1357
 aaaacactaa ggggagcgcg cgaagctgaa cttggcgctc gatgggggcc 50

 gttagccgcc ctagagcgcg cggagccgca gaggcgtagc tggactacaa 100

 cgcagtgcat ctcgggaggc caactcgact ggactgggtg agaggacaga 150

 ggtggctcga tgggcggccc gaaggccggg gatcatggcg ggaaggcggg 200

 cccagccagg ttcagccccg ccccgacccg ccgctcccca cccccggccg 250

 gcctcgcgtg ccttcccgca gcactgccgt ccccgggatg ctgagcgccc 300

 accgtctccc cgcagccccc tcatgcccgg ctgcgagctg cccgtgggca 350

 cctgcccgga catgtgcccg gccgccgagc gcgcccagcg cgaaagggag 400

 caccgcctgc accgcttgga ggtggtgccg ggttgccgcc aggacccgcc 450

 ccgcgcggat ccgcagcgcg cggtgaagga gtacagccga cccgccgccg 500

 gcaagccccg gcccccgccc agccagttgc gtccgccctc cgtgctgctg 550

 gccaccgtgc gctacctggc cggtgaggtg gcggagagcg ccgacatcgc 600

 ccgcgccgag gtggccagct tcgtggcaga ccgcttgcga gctgtgcgcc 650

 tggacctggc gctgcaggga gcgggcgacg ccgaggcagc ggtggtgctg 700

 gaggcggcgc tggccacgct gctggccgta gtggcgcggc tcgggcccga 750

 cgcggcgcgg ggacccgcgg acccggtgct gctgcaggcc caggtgcagg 800

 agggcttcgg ctcgctgcgg cgctgctacg cgcggggcgc cgggccgcac 850

 ccccgccaac ccgccttcca gggcctcttt ctgctctata acctgggtga 900

 gtcgggatcc tggcggctgg gcagagcgtg gggacaggag cccaccatga 950

 cagtggaggc tcggtggaag ccctgcatga ggttctacag ctgcctgctg 1000

 ccctgcgcgc ctgcccgccc ctccgcaagg ccttggcggt agatgctgcc 1050

 ttccgagagg gcaatgctgc ccgcctgttc cgtctgctcc agaccctgcc 1100

 ctacctgcca agttgcgctg tgcagtgcca tgtgggccat gcccgccggg 1150

 aagccctggc ccgcttcgct cgtgccttta gcacccccaa gggccagacc 1200

 ttgcctctgg gcttcatggt caacctcttg gccctggatg gactcaggga 1250

 agcacgggac ctgtgccagg cccacgggct gcccttggac ggagaggaga 1300

 gagttgtgtt cctgaggggt cgctacgtgg aggaagggct accgcctgcc 1350

 agtacgtgca aggtgttagt ggagagcaaa cttcgaggac gtaccctgga 1400

 ggaggtggtc atggcagagg aggaagatga gggcacggac agacctgggt 1450

 ccccagcctg aggagggagc gtgagcctcc cagagcccca ggactgggcc 1500

 agagcactta ggtttctttt tccatggttt ccaggtaata aaaggaactt 1550

 gttttgttgg taaaaaaaaa aaaaaaaaa 1579

<210> 1358
<211> 285
<212> PRT
<213> Homo sapien

<400> 1358
 Met Ala Gly Arg Arg Ala Gln Pro Gly Ser Ala Pro Pro Arg Pro
   1               5                  10                  15

 Ala Ala Pro His Pro Arg Pro Ala Ser Arg Ala Phe Pro Gln His
                  20                  25                  30

 Cys Arg Pro Arg Asp Ala Glu Arg Pro Pro Ser Pro Arg Ser Pro
                  35                  40                  45

 Leu Met Pro Gly Cys Glu Leu Pro Val Gly Thr Cys Pro Asp Met
                  50                  55                  60

 Cys Pro Ala Ala Glu Arg Ala Gln Arg Glu Arg Glu His Arg Leu
                  65                  70                  75

 His Arg Leu Glu Val Val Pro Gly Cys Arg Gln Asp Pro Pro Arg
                  80                  85                  90

 Ala Asp Pro Gln Arg Ala Val Lys Glu Tyr Ser Arg Pro Ala Ala
                  95                 100                 105

 Gly Lys Pro Arg Pro Pro Pro Ser Gln Leu Arg Pro Pro Ser Val
                 110                 115                 120

 Leu Leu Ala Thr Val Arg Tyr Leu Ala Gly Glu Val Ala Glu Ser
                 125                 130                 135

 Ala Asp Ile Ala Arg Ala Glu Val Ala Ser Phe Val Ala Asp Arg
                 140                 145                 150

 Leu Arg Ala Val Arg Leu Asp Leu Ala Leu Gln Gly Ala Gly Asp
                 155                 160                 165

 Ala Glu Ala Ala Val Val Leu Glu Ala Ala Leu Ala Thr Leu Leu
                 170                 175                 180

 Ala Val Val Ala Arg Leu Gly Pro Asp Ala Ala Arg Gly Pro Ala
                 185                 190                 195

 Asp Pro Val Leu Leu Gln Ala Gln Val Gln Glu Gly Phe Gly Ser
                 200                 205                 210

 Leu Arg Arg Cys Tyr Ala Arg Gly Ala Gly Pro His Pro Arg Gln
                 215                 220                 225

 Pro Ala Phe Gln Gly Leu Phe Leu Leu Tyr Asn Leu Gly Glu Ser
                 230                 235                 240

 Gly Ser Trp Arg Leu Gly Arg Ala Trp Gly Gln Glu Pro Thr Met
                 245                 250                 255

 Thr Val Glu Ala Arg Trp Lys Pro Cys Met Arg Phe Tyr Ser Cys
                 260                 265                 270

 Leu Leu Pro Cys Ala Pro Ala Arg Pro Ser Ala Arg Pro Trp Arg
                 275                 280                 285

<210> 1359
<211> 1311
<212> DNA
<213> Homo sapien

<400> 1359
 gtaagtctgc tggcctccgc catcttagta aagtaacagt cccatgaaac 50

 aaagatgcag tcgggcactc actggagagt tctgggcctc tgcctcttat 100

 cagttggcgt ttgggggcaa gatggtaatg aagaaatggg tggtattaca 150

 cagacaccat ataaagtctc catctctgga accacagtaa tattgacatg 200

 ccctcagtat cctggatctg aaatactatg gcaacacaat gataaaaaca 250

 taggcggtga tgaggatgat aaaaacatag gcagtgatga ggatcacctg 300

 tcactgaagg aattttcaga attggagcaa agtggttatt atgtctgcta 350

 ccccagagga agcaaaccag aagatgcgaa cttttatctc tacctgaggg 400

 caagagtgtg tgagaactgc atggagatgg atgtgatgtc ggtggccaca 450

 attgtcatag tggacatctg catcactggg ggcttgctgc tgctggttta 500

 ctactggagc aagaatagaa aggccaaggc caagcctgtg acacgaggag 550

 cgggtgctgg cggcaggcaa aggggacaaa acaaggagag gccaccacct 600

 gttcccaacc cagactatga gcccatccgg aaaggccagc gggacctgta 650

 ttctggcctg aatcagagac gcatctgacc ctctggagaa cactgcctcc 700

 cgctggccca ggtctcctct ccagtccccc tgcgactccc tgtttcctgg 750

 gctagtcttg gaccccacga gagagaatcg ttcctcagcc tcatggtgaa 800

 ctcgcgccct ccagcctgat cccccgctcc ctcctccctg ccttctctgc 850

 tggtacccag tcctaaaata ttgctgcttc ctcttccttt gaagcatcat 900

 cagtagtcac accctcacag ctggcctgcc ctcttgccag gatatttatt 950

 tgtgctattc actcccttcc ctttggatgt aacttctccg ttcagttccc 1000

 tccttttctt gcatgtaagt tgtcccccat cccaaagtat tccatctact 1050

 tttctatcgc cgtccccttt tgcagccctc tctggggatg gactgggtaa 1100

 atgttgacag aggccctgcc ccgttcacag atcctggccc tgagccagcc 1150

 ctgtgctcct ccctccccca acactcccta ccaaccccct aatcccctac 1200

 tccctccaac cccccctccc actgtaggcc actggatggt catttggcat 1250

 ctccgtatat gtgctctggc tcctcagctg agagagaaaa aaataaactg 1300

 tatttggctg c 1311

<210> 1360
<211> 207
<212> PRT
<213> Homo sapien

<400> 1360
 Met Gln Ser Gly Thr His Trp Arg Val Leu Gly Leu Cys Leu Leu
   1               5                  10                  15

 Ser Val Gly Val Trp Gly Gln Asp Gly Asn Glu Glu Met Gly Gly
                  20                  25                  30

 Ile Thr Gln Thr Pro Tyr Lys Val Ser Ile Ser Gly Thr Thr Val
                  35                  40                  45

 Ile Leu Thr Cys Pro Gln Tyr Pro Gly Ser Glu Ile Leu Trp Gln
                  50                  55                  60

 His Asn Asp Lys Asn Ile Gly Gly Asp Glu Asp Asp Lys Asn Ile
                  65                  70                  75

 Gly Ser Asp Glu Asp His Leu Ser Leu Lys Glu Phe Ser Glu Leu
                  80                  85                  90

 Glu Gln Ser Gly Tyr Tyr Val Cys Tyr Pro Arg Gly Ser Lys Pro
                  95                 100                 105

 Glu Asp Ala Asn Phe Tyr Leu Tyr Leu Arg Ala Arg Val Cys Glu
                 110                 115                 120

 Asn Cys Met Glu Met Asp Val Met Ser Val Ala Thr Ile Val Ile
                 125                 130                 135

 Val Asp Ile Cys Ile Thr Gly Gly Leu Leu Leu Leu Val Tyr Tyr
                 140                 145                 150

 Trp Ser Lys Asn Arg Lys Ala Lys Ala Lys Pro Val Thr Arg Gly
                 155                 160                 165

 Ala Gly Ala Gly Gly Arg Gln Arg Gly Gln Asn Lys Glu Arg Pro
                 170                 175                 180

 Pro Pro Val Pro Asn Pro Asp Tyr Glu Pro Ile Arg Lys Gly Gln
                 185                 190                 195

 Arg Asp Leu Tyr Ser Gly Leu Asn Gln Arg Arg Ile
                 200                 205

<210> 1361
<211> 799
<212> DNA
<213> Homo sapien

<400> 1361
 cactcccaaa gaactgggta ctcaacactg agcagatctg ttctttgagc 50

 taaaaaccat gtgctgtacc aagagtttgc tcctggctgc tttgatgtca 100

 gtgctgctac tccacctctg cggcgaatca gaagcagcaa gcaactttga 150

 ctgctgtctt ggatacacag accgtattct tcatcctaaa tttattgtgg 200

 gcttcacacg gcagctggcc aatgaaggct gtgacatcaa tgctatcatc 250

 tttcacacaa agaaaaagtt gtctgtgtgc gcaaatccaa aacagacttg 300

 ggtgaaatat attgtgcgtc tcctcagtaa aaaagtcaag aacatgtaaa 350

 aactgtggct tttctggaat ggaattggac atagcccaag aacagaaaga 400

 accttgctgg ggttggaggt ttcacttgca catcatggag ggtttagtgc 450

 ttatctaatt tgtgcctcac tggacttgtc caattaatga agttgattca 500

 tattgcatca tagtttgctt tgtttaagca tcacattaaa gttaaactgt 550

 attttatgtt atttatagct gtaggttttc tgtgtttagc tatttaatac 600

 taattttcca taagctattt tggtttagtg caaagtataa aattatattt 650

 gggggggaat aagattatat ggactttctt gcaagcaaca agctattttt 700

 taaaaaaact atttaacatt cttttgttta tattgttttg tctcctaaat 750

 tgttgtaatt gcattataaa ataagaaaaa cattaataag acaaatatt 799

<210> 1362
<211> 96
<212> PRT
<213> Homo sapien

<400> 1362
 Met Cys Cys Thr Lys Ser Leu Leu Leu Ala Ala Leu Met Ser Val
   1               5                  10                  15

 Leu Leu Leu His Leu Cys Gly Glu Ser Glu Ala Ala Ser Asn Phe
                  20                  25                  30

 Asp Cys Cys Leu Gly Tyr Thr Asp Arg Ile Leu His Pro Lys Phe
                  35                  40                  45

 Ile Val Gly Phe Thr Arg Gln Leu Ala Asn Glu Gly Cys Asp Ile
                  50                  55                  60

 Asn Ala Ile Ile Phe His Thr Lys Lys Lys Leu Ser Val Cys Ala
                  65                  70                  75

 Asn Pro Lys Gln Thr Trp Val Lys Tyr Ile Val Arg Leu Leu Ser
                  80                  85                  90

 Lys Lys Val Lys Asn Met
                  95

<210> 1363
<211> 634
<212> DNA
<213> Homo sapien

<400> 1363
 cggctgagag gcagcgaact catctttgcc agtacaggag cttgtgccgt 50

 ggcccacagc ccacagccca cagccatggg ctgggacctg acggtgaaga 100

 tgctggcggg caacgaattc caggtgtccc tgagcagctc catgtcggtg 150

 tcagagctga aggcgcagat cacccagaag attggcgtgc acgccttcca 200

 gcagcgtctg gctgtccacc cgagcggtgt ggcgctgcag gacagggtcc 250

 cccttgccag ccagggcctg ggccctggca gcacggtcct gctggtggtg 300

 gacaaatgcg acgaacctct gagcatcctg gtgaggaata acaagggccg 350

 cagcagcacc tacgaggtcc ggctgacgca gaccgtggcc cacctgaagc 400

 agcaagtgag cgggctggag ggtgtgcagg acgacctgtt ctggctgacc 450

 ttcgagggga agcccctgga ggaccagctc ccgctggggg agtacggcct 500

 caagcccctg agcaccgtgt tcatgaatct gcgcctgcgg ggaggcggca 550

 cagagcctgg cgggcggagc taagggcctc caccagcatc cgagcaggat 600

 caagggccgg aaataaaggc tgttgtaaga gaat 634

<210> 1364
<211> 165
<212> PRT
<213> Homo sapien

<400> 1364
 Met Gly Trp Asp Leu Thr Val Lys Met Leu Ala Gly Asn Glu Phe
   1               5                  10                  15

 Gln Val Ser Leu Ser Ser Ser Met Ser Val Ser Glu Leu Lys Ala
                  20                  25                  30

 Gln Ile Thr Gln Lys Ile Gly Val His Ala Phe Gln Gln Arg Leu
                  35                  40                  45

 Ala Val His Pro Ser Gly Val Ala Leu Gln Asp Arg Val Pro Leu
                  50                  55                  60

 Ala Ser Gln Gly Leu Gly Pro Gly Ser Thr Val Leu Leu Val Val
                  65                  70                  75

 Asp Lys Cys Asp Glu Pro Leu Ser Ile Leu Val Arg Asn Asn Lys
                  80                  85                  90

 Gly Arg Ser Ser Thr Tyr Glu Val Arg Leu Thr Gln Thr Val Ala
                  95                 100                 105

 His Leu Lys Gln Gln Val Ser Gly Leu Glu Gly Val Gln Asp Asp
                 110                 115                 120

 Leu Phe Trp Leu Thr Phe Glu Gly Lys Pro Leu Glu Asp Gln Leu
                 125                 130                 135

 Pro Leu Gly Glu Tyr Gly Leu Lys Pro Leu Ser Thr Val Phe Met
                 140                 145                 150

 Asn Leu Arg Leu Arg Gly Gly Gly Thr Glu Pro Gly Gly Arg Ser
                 155                 160                 165

<210> 1365
<211> 1232
<212> DNA
<213> Homo sapien

<400> 1365
 gccaccacca gtattgggga tgctgagctg cggggtacgg gcctgaggag 50

 ggatgggagt aagaagtgct gtggaaaccg tcaggccatg aaccaggctg 100

 accctcggct cagagcagtg tgcttgtgga ctctcacatc tgcagccatg 150

 agcagaggcg acaactgcac ggatctactc gcactgggaa tcccctccat 200

 aacccaggcc tggggactgt gggtcctctt aggggctgtg acgctgctat 250

 ttctcatctc gctggctgca cacttgtccc agtggaccag gggccggagc 300

 aggagccatc cggggcaggg acgctctgga gagtctgtgg aagaggtccc 350

 gctgtatggg aacctgcatt atctacagac aggacggctg tctcaagacc 400

 cagagccaga ccagcaggat ccaactcttg gaggccctgc cagggctgca 450

 gaggaggtga tgtgctatac cagcctgcag ctgcggcctc ctcagggtcg 500

 gatccccggt cctggaaccc ccgtcaagta ctcggaggtg gtgctggact 550

 ctgagccaaa gtcccaggcc tcgggccccg agccggagct ctatgcctca 600

 gtatgtgccc agacccgcag ggcccgggcc tccttcccgg atcaggccta 650

 tgccaacagc cagcctgcag ccagctgaga tggagggcct ggcacagcgg 700

 ggcgtgcact gccccagccc cccgtagcag gggcatgact gtttcccaac 750

 cagcacccaa agacgggctg ccattgccaa gtcacaggat gtgatctacc 800

 ccggacttcc tatctgagct tcaagggaga catctcaggg caaagctttc 850

 gtgatggagg aggcaaagac agtagccccc tccttatttc ttttttctat 900

 ctgttcctct tagcccccaa actcccaggt tctcacttcc ttcttctgga 950

 gtttaaccag atcctcccca cccccgctcc ctcatagtct acccccacgc 1000

 ctcagtgtct cctcaggcac aggaagtggg cggtggggga ggggtaaggg 1050

 cctgacagtg ggtgggtggg tatattcctc aggagtccac agactggagt 1100

 ggacctggaa cttagagacg ggagggaccc gagcctggct tttgacctaa 1150

 gaaccctagc aggagaatac agtctccatc ctgctgtctc tgtcctgtcc 1200

 caagttttca aataaaactt tccaaaaaag tg 1232

<210> 1366
<211> 196
<212> PRT
<213> Homo sapien

<400> 1366
 Met Asn Gln Ala Asp Pro Arg Leu Arg Ala Val Cys Leu Trp Thr
   1               5                  10                  15

 Leu Thr Ser Ala Ala Met Ser Arg Gly Asp Asn Cys Thr Asp Leu
                  20                  25                  30

 Leu Ala Leu Gly Ile Pro Ser Ile Thr Gln Ala Trp Gly Leu Trp
                  35                  40                  45

 Val Leu Leu Gly Ala Val Thr Leu Leu Phe Leu Ile Ser Leu Ala
                  50                  55                  60

 Ala His Leu Ser Gln Trp Thr Arg Gly Arg Ser Arg Ser His Pro
                  65                  70                  75

 Gly Gln Gly Arg Ser Gly Glu Ser Val Glu Glu Val Pro Leu Tyr
                  80                  85                  90

 Gly Asn Leu His Tyr Leu Gln Thr Gly Arg Leu Ser Gln Asp Pro
                  95                 100                 105

 Glu Pro Asp Gln Gln Asp Pro Thr Leu Gly Gly Pro Ala Arg Ala
                 110                 115                 120

 Ala Glu Glu Val Met Cys Tyr Thr Ser Leu Gln Leu Arg Pro Pro
                 125                 130                 135

 Gln Gly Arg Ile Pro Gly Pro Gly Thr Pro Val Lys Tyr Ser Glu
                 140                 145                 150

 Val Val Leu Asp Ser Glu Pro Lys Ser Gln Ala Ser Gly Pro Glu
                 155                 160                 165

 Pro Glu Leu Tyr Ala Ser Val Cys Ala Gln Thr Arg Arg Ala Arg
                 170                 175                 180

 Ala Ser Phe Pro Asp Gln Ala Tyr Ala Asn Ser Gln Pro Ala Ala
                 185                 190                 195

 Ser


<210> 1367
<211> 15359
<212> DNA
<213> Homo sapien

<400> 1367
 tctacctcgc gggtgcctct ggtgtctcca gaggtctccg accccagccc 50

 gcccccagcc ctcccgccca gcccgcagcc ccctccctct gttccccgac 100

 ctcagaccct gggcttccga cctcgacatc atgggtgacg cagaaggcga 150

 agacgaggtc cagttcctgc ggacggacga tgaggtggtc ctgcagtgca 200

 gcgctaccgt gctcaaggag cagctcaagc tctgcctggc cgccgagggc 250

 ttcggcaacc gcctgtgctt cctggagccc actagcaacg cgcagaatgt 300

 gccccccgat ctggccatct gttgcttcgt cctggagcag tccctgtctg 350

 tgcgagccct gcaggagatg ctggctaaca cggtggaggc tggcgtggag 400

 tcatcccagg gcgggggaca caggacgctc ctgtatggcc atgccatcct 450

 gctccggcat gcacacagcc gcatgtatct gagctgcctc accacctccc 500

 gctccatgac tgacaagctg gccttcgatg tgggactgca ggaggacgca 550

 acaggagagg cttgctggtg gaccatgcac ccagcctcca agcagaggtc 600

 tgaaggagaa aaggtccgcg ttggggatga catcatcctt gtcagtgtct 650

 cctccgagcg ctacctgcac ctgtcgaccg ccagtgggga gctccaggtt 700

 gacgcttcct tcatgcagac actgtggaac atgaacccca tctgctcccg 750

 ctgcgaagag ggcttcgtga cgggaggtca cgtcctccgc ctctttcatg 800

 gacatatgga tgagtgtctg accatttccc ctgctgacag tgatgaccag 850

 cgcagacttg tctactatga ggggggagct gtgtgcactc atgcccgctc 900

 cctctggagg ctggagccac tgagaatcag ctggagtggg agccacctgc 950

 gctggggcca gccactccga gtccggcatg tcactaccgg gcagtaccta 1000

 gcgctcaccg aggaccaggg cctggtggtg gttgacgcca gcaaggctca 1050

 caccaaggct acctccttct gcttccgcat ctccaaggag aagctggatg 1100

 tggcccccaa gcgggatgtg gagggcatgg gcccccctga gatcaagtac 1150

 ggggagtcac tgtgcttcgt gcagcatgtg gcctcaggac tgtggctcac 1200

 ctatgccgct ccagacccca aggccctgcg gctcggcgtg ctcaagaaga 1250

 aggccatgct gcaccaggag ggccacatgg acgacgcact gtcgctgacc 1300

 cgctgccagc aggaggagtc ccaggccgcc cgcatgatcc acagcaccaa 1350

 tggcctatac aaccagttca tcaagagcct ggacagcttc agcgggaagc 1400

 cacggggctc ggggccaccc gctggcacgg cgctgcccat cgagggcgtt 1450

 atcctgagcc tgcaggacct catcatctac ttcgagcctc cctccgagga 1500

 cttgcagcac gaggagaagc agagcaagct gcgaagcctg cgcaaccgcc 1550

 agagcctctt ccaggaggag gggatgctct ccatggtcct gaattgcata 1600

 gaccgcctaa atgtctacac cactgctgcc cactttgctg agtttgcagg 1650

 ggaggaggca gccgagtcct ggaaagagat tgtgaatctt ctctatgaac 1700

 tcctagcttc tctaatccgt ggcaatcgta gcaactgtgc cctcttctcc 1750

 acaaacttgg actggctggt cagcaagctg gatcggctgg aggcctcgtc 1800

 tggcatcctg gaggtcctgt actgtgtcct cattgagagt ccagaggttc 1850

 tgaacatcat ccaggagaat cacatcaagt ccatcatctc cctcctggac 1900

 aagcatggga ggaaccacaa ggtcctggac gtgctatgct ccctgtgtgt 1950

 gtgtaatggt gtggctgtac gctccaacca agatcttatt actgagaact 2000

 tgctgcctgg ccgtgagctt ctgctgcaga caaacctcat caactatgtc 2050

 accagcatcc gccccaacat ctttgtgggc cgagcggaag gcaccacgca 2100

 gtacagcaaa tggtactttg aggtgatggt ggacgaggtg actccatttc 2150

 tgacagctca ggccacccac ttgcgggtgg gctgggccct caccgagggc 2200

 tacaccccct accctggggc cggcgagggc tggggcggca acggggtcgg 2250

 cgatgacctc tattcctacg gctttgatgg actgcatctc tggacaggac 2300

 acgtggcacg cccagtgact tccccagggc agcacctcct ggcccctgaa 2350

 gacgtgatca gctgctgcct ggacctcagc gtgccgtcca tctccttccg 2400

 catcaacggc tgccctgtgc agggtgtctt tgagtccttc aacctggacg 2450

 ggctcttctt ccctgttgtc agcttctcgg ctggtgtcaa ggtgcggttc 2500

 ctccttggtg gccgccatgg tgaattcaag ttcctgcccc cacctggcta 2550

 tgctccatgc catgaggctg tgctccctcg agagcgactc catcttgaac 2600

 ccatcaagga gtatcgacgg gaggggcccc gggggcctca cctggtgggc 2650

 cccagtcgct gcctctcaca caccgacttc gtgccctgcc ctgtggacac 2700

 tgtccagatt gtcctgccgc cccatctgga gcgcattcgg gagaagctgg 2750

 cggagaacat ccacgagctc tgggcgctaa cccgcatcga gcagggctgg 2800

 acctacggcc cggttcggga tgacaacaag aggctgcacc cgtgtcttgt 2850

 ggacttccac agccttccag agcctgagag gaactacaac ctgcagatgt 2900

 ctggggagac gctcaagact ctgctggctc tgggctgcca cgtgggcatg 2950

 gcggatgaga aggcggagga caacctgaag aagacaaaac tccccaagac 3000

 gtatatgatg agcaatgggt acaagccggc tccgctggac ctgagccacg 3050

 tgcggctgac gccggcgcag acaacactgg tggaccgtct ggcagaaaat 3100

 gggcacaacg tgtgggcccg agaccgcgtg ggccagggct ggagctacag 3150

 cgcagtgcag gacatcccag cgcgccgaaa ccctcggctg gtgccctacc 3200

 gcctgctgga tgaagccacc aagcgcagca accgggacag cctctgccag 3250

 gccgtgcgca ccctcctggg ctacggctac aacatcgagc ctcctgacca 3300

 ggagcccagt caggtggaga accagtctcg ttgtgaccgg gtgcgcatct 3350

 tccgggcaga gaaatcctat acagtgcaga gcggccgctg gtacttcgag 3400

 tttgaagcag tcaccacagg cgagatgcgc gtgggctggg cgaggcccga 3450

 gctgaggcct gatgtagagc tgggagctga cgagctggcc tatgtcttca 3500

 atgggcaccg cggccagcgc tggcacttgg gcagtgaacc atttgggcgc 3550

 ccctggcagc cgggcgatgt cgttggctgt atgatcgacc tcacagagaa 3600

 caccattatc ttcaccctca atggcgaggt cctcatgtct gactcaggct 3650

 ccgaaacagc cttccgggag attgagattg gggacggctt cctgcccgtc 3700

 tgcagcttgg gacctggcca ggtgggtcat ctgaacctgg gccaggacgt 3750

 gagctctctg aggttctttg ccatctgtgg cctccaggaa ggcttcgagc 3800

 catttgccat caacatgcag cgcccagtca ccacctggtt cagcaaaggc 3850

 ctgccccagt ttgagccagt gccccttgaa caccctcact atgaggtatc 3900

 ccgagtggac ggcactgtgg acacgccccc ctgcctgcgc ctgacccacc 3950

 gcacctgggg ctcccagaac agcctggtgg agatgctttt cctgcggctg 4000

 agcctcccag tccagttcca ccagcacttc cgctgcactg caggggccac 4050

 cccgctggca cctcctggcc tgcagccccc cgccgaggac gaggcccggg 4100

 cggcggaacc cgaccctgac tacgaaaacc tgcgccgctc agctgggggc 4150

 tggagcgagg cagagaacgg caaagaaggg actgcgaagg agggcgcccc 4200

 cgggggcacc ccgcaggcgg ggggagaggc gcagcccgcc agggcggaga 4250

 atgagaagga tgccaccacc gagaagaaca agaagagagg cttcttattc 4300

 aaggccaaga aggtcgccat gatgacccag ccaccggcca cccccacgct 4350

 gccccgactc cctcacgacg tggtgcctgc agacaaccgc gatgaccccg 4400

 agatcatcct caacaccacc acgtactatt actccgtgag ggtctttgct 4450

 ggacaggagc ccagctgcgt gtgggcgggc tgggtcaccc ctgactacca 4500

 tcagcacgac atgagcttcg acctcagcaa ggtccgggtc gtgacggtga 4550

 ccatggggga tgaacaaggc aacgtccaca gcagcctcaa gtgtagcaac 4600

 tgctacatgg tgtggggcgg agactttgtg agtcccgggc agcagggccg 4650

 gatcagccac acggaccttg tcattgggtg cctggtggac ttggccactg 4700

 gcttaatgac ctttacagcc aatggcaaag agagcaacac ctttttccag 4750

 gtggaaccca acactaagct atttcctgcc gtcttcgtcc tgcccaccca 4800

 ccagaacgtc atccagtttg agctggggaa gcagaagaac atcatgccgt 4850

 tgtcagccgc catgttccaa agcgagcgca agaacccggc cccgcagtgc 4900

 ccaccgcggc tggagatgca gatgctgatg ccagtgtcct ggagccgcat 4950

 gcccaaccac ttcctgcagg tggagacgag gcgtgccggc gagcggctgg 5000

 gctgggccgt gcagtgccag gagccgctga ccatgatggc gctgcacatc 5050

 cccgaggaga accggtgcat ggacatcctg gagctgtcgg agcgcctgga 5100

 cctgcagcgc ttccactcgc acaccctgcg cctctaccgc gctgtgtgcg 5150

 ccctgggcaa caatcgcgtg gcgcacgctc tgtgcagcca cgtagaccaa 5200

 gctcagctgc tgcacgccct ggaggacgcg cacctgccag gcccactgcg 5250

 cgcaggctac tatgacctcc tcatcagcat ccacctcgaa agtgcctgcc 5300

 gcagccgccg ctccatgctc tctgaataca tcgtgcccct cacgcctgag 5350

 acccgcgcca tcacgctctt ccctcctgga aggagcacag aaaatggtca 5400

 cccccggcat ggcctgccgg gagttggagt caccacttcg ctgaggcccc 5450

 cgcatcattt ctcgcccccc tgtttcgtgg ccgctctgcc agctgctggg 5500

 gcagcagagg ccccggcccg cctcagccct gccatcccgc tggaggccct 5550

 gcgggacaag gcactgagga tgctggggga ggcggtgcgc gacggtgggc 5600

 agcacgctcg cgaccccgtc ggggcctccg tggagttcca gtttgtgcct 5650

 gtgctcaagc tcgtgtccac cctgctggtg atgggcatct ttggcgatga 5700

 ggatgtgaaa cagatcttga agatgattga gcctgaggtc ttcactgagg 5750

 aagaggagga ggaggacgag gaggaagagg gtgaagagga agatgaggag 5800

 gagaaggagg aggatgagga ggaaacagca caggaaaagg aagatgagga 5850

 aaaagaggaa gaggaggcag cagaagggga gaaagaagaa ggcttggagg 5900

 aagggctgct ccagatgaag ttgccagagt ctgtgaagtt acagatgtgc 5950

 cacctgctgg agtatttctg tgaccaagag ctgcagcacc gtgtggagtc 6000

 cctggcagcc tttgcggagc gctatgtgga caagctccag gccaaccagc 6050

 ggagccgcta tggcctcctc ataaaagcct tcagcatgac cgcagcagag 6100

 actgcaagac gtacccgtga gttccgctcc ccaccccagg aacagatcaa 6150

 tatgctattg caattcaaag atggtacaga tgaggaagac tgtcctctcc 6200

 ctgaagagat tcgacaggat ttgcttgact ttcatcaaga cctgctggca 6250

 cactgtggaa ttcagctaga tggagaggag gaggaaccag aggaagagac 6300

 caccctgggc agccgcctca tgagcctgtt ggagaaagtg cggctggtga 6350

 agaagaagga agagaaacct gaggaggagc ggtcagcaga ggagagcaaa 6400

 ccccggtccc tgcaggagct ggtgtcccac atggtggtgc gctgggccca 6450

 agaggacttc gtgcagagcc ccgagctggt gcgggccatg ttcagcctcc 6500

 tgcaccggca gtacgacggg ctgggtgagc tgctgcgtgc cctgccgcgg 6550

 gcgtacacca tctcaccgtc ctccgtggaa gacaccatga gcctgctcga 6600

 gtgcctcggc cagatccgct cgctgctcat cgtgcagatg ggcccccagg 6650

 aggagaacct catgatccag agcatcggga acatcatgaa caacaaagtc 6700

 ttctaccaac acccgaacct gatgagggcg ctgggcatgc acgagacggt 6750

 catggaggtc atggtcaacg tcctcggggg cggcgagtcc aaggagatcc 6800

 gcttccccaa gatggtgaca agctgctgcc gcttcctctg ctatttctgc 6850

 cgaatcagcc ggcagaacca gcgctccatg tttgaccacc tgagctacct 6900

 gctggagaac agtggcatcg gcctgggcat gcagggctcc acgcccctgg 6950

 acgtggctgc tgcctccgtc attgacaaca atgagctggc cttggcattg 7000

 caggagcagg acctggaaaa ggttgtgtcc tacctggcag gctgtggcct 7050

 ccagagctgc cccatgcttg tggccaaagg gtacccagac attggctgga 7100

 acccctgtgg tggagagcgc tacctggact tcctgcgctt tgctgtcttc 7150

 gtcaacggcg agagcgtgga ggagaacgcc aatgtggtgg tgcggctgct 7200

 catccggaag cctgagtgct tcggacccgc cctgcggggt gagggtggct 7250

 cagggctgct ggctgccatc gaagaggcca tccgcatctc cgaggaccct 7300

 gcgagggatg gcccaggcat ccgcagggac cggcggcgcg agcactttgg 7350

 tgaggaaccg cctgaagaaa accgggtgca cctgggacac gccatcatgt 7400

 ccttctatgc cgccttgatc gacctgctcg gacgctgtgc accagagatg 7450

 catctaatcc aagccggcaa gggtgaggcc ctgcggatcc gcgccatcct 7500

 ccgctccctt gtgcccttgg aggaccttgt gggcatcatc agcctcccac 7550

 tgcagattcc caccctgggc aaagatgggg ctctggtgca gccaaagatg 7600

 tcagcatcct tcgtgccgga ccacaaggcg tccatggtgc tcttcctgga 7650

 ccgtgtgtat ggcatcgaga accaggactt cttgctgcac gtgctggacg 7700

 tggggttcct gcccgacatg agggcagccg cctcgctgga cacggccact 7750

 ttcagcacca ccgagatggc gctggccgtg aaccgctacc tgtgcctggc 7800

 cgtgctgccg ctcatcacca agtgtgcgcc gctctttgcg ggcacagaac 7850

 accgcgccat catggtggac tctatgctgc ataccgtgta ccgcctgtct 7900

 cggggtcgtt cgctcaccaa ggcgcagcgt gacgtcatcg aggactgcct 7950

 catgtcgctc tgcaggtaca tccgcccgtc gatgctgcag cacctgttgc 8000

 gccgcctggt gttcgacgtg cccatcctca acgagttcgc caagatgcca 8050

 ctcaagctcc tcaccaacca ctatgagcgc tgttggaagt actactgcct 8100

 acccacgggc tgggccaact tcggggtcac ctcagaggag gagctgcacc 8150

 tcacacggaa actcttctgg ggcatctttg actctctggc ccataagaaa 8200

 tacgacccgg agctgtaccg catggccatg ccttgtctgt gcgccattgc 8250

 cggggctctg ccccccgact atgtggatgc ctcatactca tctaaggcag 8300

 agaaaaaggc cacagtggat gctgaaggca actttgatcc ccggcctgtg 8350

 gagaccctca atgtgatcat cccggagaag ctggactcct tcattaacaa 8400

 gtttgcggag tacacacacg agaagtgggc cttcgacaag atccagaaca 8450

 actggtccta tggagagaac atagacgagg agctgaagac ccaccccatg 8500

 ctgaggccct acaagacctt ttcagagaag gacaaagaga tttaccgctg 8550

 gcccatcaag gagtccctga aggccatgat tgcctgggaa tggacgatag 8600

 agaaggccag ggagggtgag gaggagaaga cggaaaagaa aaaaacgcgg 8650

 aagatatcac aaagtgccca gacctatgat cctcgagaag gctacaaccc 8700

 tcagcccccc gaccttagtg ctgttaccct gtcccgggag ctgcaggcca 8750

 tggcagaaca actggcagaa aattaccaca acacgtgggg acggaagaag 8800

 aagcaggagc tggaagccaa aggcggtggg acccaccccc tgctggtccc 8850

 ctacgacacg ctcacggcca aggagaaggc acgagatcga gagaaggccc 8900

 aggagctact gaaattcctg cagatgaatg gctacgcggt tacaagaggc 8950

 cttaaggaca tggaactgga ctcgtcttcc attgaaaagc ggtttgcctt 9000

 tggcttcctg cagcagctgc tgcgctggat ggacatttct caggagttca 9050

 ttgcccacct ggaggctgtg gtcagcagtg ggcgagtgga aaagtcccca 9100

 catgaacagg agattaaatt ctttgccaag atcctgctcc ctttgatcaa 9150

 ccagtacttc accaaccact gcctctattt cttgtccact ccggctaaag 9200

 tgctgggcag cggtggccac gcctctaaca aggagaagga aatgatcacc 9250

 agcctcttct gcaaacttgc tgctctcgtc cgccaccgag tctctctctt 9300

 tgggacagac gccccagctg tggtcaactg tcttcacatc ctggcccgct 9350

 ccctggatgc caggacagtg atgaagtcag gccctgagat cgtgaaggct 9400

 ggcctccgct ccttcttcga gagtgcctcg gaggacatcg agaagatggt 9450

 ggagaacctg cggctgggca aggtgtcgca ggcgcgcacc caggtgaaag 9500

 gcgtgggcca gaacctcacc tacaccactg tggcactgct gccggtcctc 9550

 accaccctct tccagcacat cgcccagcac cagttcggag atgacgtcat 9600

 cctggacgac gtccaggtct cttgctaccg aacgctgtgc agtatctact 9650

 ccctgggaac caccaagaac acttatgtgg aaaagcttcg gccagccctc 9700

 ggggagtgcc tggcccgtct ggcagcagcc atgccggtgg cgttcctgga 9750

 gccgcagctg aacgagtaca acgcctgctc cgtgtacacc accaagtctc 9800

 cgcgggagcg ggccatcctg gggctcccca acagtgtgga ggagatgtgt 9850

 cccgacatcc cggtgctgga gcggctcatg gcagacattg gggggctggc 9900

 cgagtcaggt gcccgctaca cagagatgcc gcatgtcatc gagatcacgc 9950

 tgcccatgct atgcagctac ctgccccgat ggtgggagcg cgggcccgag 10000

 gcaccccctt ccgccctgcc cgccggcgcc cccccaccct gcacagctgt 10050

 cacctctgac cacctcaact ccctgctggg gaatatcctg agaatcatcg 10100

 tcaacaacct gggcattgac gaggcctcct ggatgaagcg gctggctgtg 10150

 ttcgcacagc ccattgtgag ccgtgcacgg ccggagctcc tgcagtccca 10200

 cttcatccca actatcgggc ggctgcgcaa gagggcaggg aaggtggtgt 10250

 ccgaggagga gcagctgcgc ctggaggcca aggcggaggc ccaggagggc 10300

 gagctgctgg tgcgggacga gttctctgtg ctctgccggg acctctacgc 10350

 cctgtatccg ctgctcatcc gctacgtgga caacaacagg gcgcagtggc 10400

 tgacggagcc gaatcccagc gcggaggagc tgttcaggat ggtgggcgag 10450

 atcttcatct actggtccaa gtcccacaac ttcaagcgcg aggagcagaa 10500

 ctttgtggtc cagaatgaga tcaacaacat gtccttcctg actgctgaca 10550

 acaaaagcaa aatggctaag gcgggagata tacagtccgg tggctcggac 10600

 caggaacgca ccaagaagaa gcgccggggg gaccggtact ctgtgcagac 10650

 gtcactgatc gtggccacac tgaagaagat gctgcccatc ggcctgaata 10700

 tgtgtgcgcc caccgaccaa gacctcatca cgctggccaa gacccgttac 10750

 gccctgaaag acacagatga ggaggtccgg gaatttctgc acaacaacct 10800

 tcaccttcag ggaaaggtcg aaggctcccc gtctctgcgc tggcagatgg 10850

 ctctgtaccg gggcgtcccg ggtcgcgagg aggacgccga tgaccccgag 10900

 aaaatcgtgc gcagagtcca ggaagtgtca gccgtgctct actacctgga 10950

 ccagaccgag cacccttaca agtctaagaa ggccgtgtgg cacaagcttt 11000

 tgtccaaaca gcgccggcgg gcagtcgtgg cctgtttccg tatgacgccc 11050

 ctgtacaacc tgcccacgca ccgggcatgt aacatgttcc tggagagcta 11100

 caaggctgca tggatcctga ctgaagacca cagttttgag gaccgcatga 11150

 tagatgacct ttcaaaagct ggggagcagg aggaggagga ggaagaggtg 11200

 gaagagaaga agccagaccc cctgcaccag ttggtcctgc acttcagccg 11250

 cactgccctg acggaaaaga gcaaactgga tgaggattac ctgtacatgg 11300

 cctatgctga tatcatggca aagagctgcc acctggagga gggaggggag 11350

 aacggtgaag ctgaagagga ggttgaggtc tcctttgagg agaaacagat 11400

 ggagaagcag aggctcttgt accagcaagc acggctgcac acccgggggg 11450

 cggccgagat ggtgctgcag atgatcagtg cctgcaaagg agagacaggt 11500

 gccatggtgt cctccaccct gaagctgggc atctccatcc tcaatggagg 11550

 caatgctgag gtccagcaga aaatgctgga ttatcttaag gacaagaagg 11600

 aagttggctt cttccagagt atccaggcac tgatgcaaac atgcagcgtc 11650

 ctggatctca atgcctttga gagacaaaac aaggccgagg ggctgggcat 11700

 ggtgaatgag gatggcactg tcatcaatcg ccagaacgga gagaaggtca 11750

 tggcggatga tgaattcaca caagacctgt tccgattcct acaattgctc 11800

 tgtgaggggc acaataatga tttccagaac tacctacgga cacagacagg 11850

 gaacacgacc actattaaca tcatcatttg cactgtggac tacctcctgc 11900

 ggctgcagga atccatcagc gacttctact ggtactactc gggcaaggat 11950

 gtcattgaag agcagggcaa gaggaacttc tccaaagcca tgtcggtggc 12000

 taagcaggtg ttcaacagcc tcactgagta catccagggt ccctgcaccg 12050

 ggaaccagca gagcctggcg cacagtcgcc tatgggacgc agtggtggga 12100

 ttcctgcacg tgttcgccca catgatgatg aagctcgctc aggactcaag 12150

 ccagatcgag ctgctgaagg agctgctgga tctgcagaag gacatggtgg 12200

 tgatgttgct gtcgctacta gaagggaacg tggtgaacgg catgatcgcc 12250

 cggcagatgg tggacatgct cgtggaatcc tcatccaatg tggagatgat 12300

 cctcaagttc ttcgacatgt tcctgaaact caaggacatt gtgggctctg 12350

 aagccttcca ggactacgta acggatcccc gtggcctcat ctccaagaag 12400

 gacttccaga aggccatgga cagccagaag cagttcagcg gtccagaaat 12450

 ccagttcctg ctttcgtgct ccgaagcgga tgagaacgaa atgatcaact 12500

 gcgaagagtt cgccaaccgc ttccaggagc cagcacgcga catcggcttc 12550

 aacgtggcgg tgctgctgac caacctgtcg gagcatgtgc cgcatgaccc 12600

 tcgcctgcac aacttcctgg agctggccga gagcatcctt gagtacttcc 12650

 gcccctacct gggccgcatc gagatcatgg gcgcgtcacg ccgcatcgag 12700

 cgcatctact tcgagatctc agagaccaac cgcgcccagt gggagatgcc 12750

 ccaggtgaag gagtccaagc gccagttcat cttcgacgtg gtgaacgagg 12800

 gcggcgaggc tgagaagatg gagctcttcg tgagtttctg cgaggacacc 12850

 atcttcgaga tgcagatcgc cgcgcagatc tcggagcccg agggcgagcc 12900

 ggagaccgac gaggacgagg gcgcgggcgc ggcggaggcg ggcgcggaag 12950

 gcgcggagga gggcgcggcg gggctcgagg gcacggcggc cacggcggcg 13000

 gcgggggcga cggcgcgggt tgtggcggcc gcaggccggg ccctgcgagg 13050

 cctcagctac cgcagcctgc ggcggcgcgt gcggcggctg cggcggctta 13100

 cggcccgcga ggcggccacc gcagtggcgg cgctgctctg ggcagcagtg 13150

 acgcgcgctg gggccgctgg cgcgggggcg gcggcgggcg cgctgggcct 13200

 gctctggggc tcgctgttcg gcggcggcct ggtggagggc gccaagaagg 13250

 tgacggtgac cgagctcctg gcaggcatgc ccgaccccac cagcgacgag 13300

 gtgcacggcg agcagccggc cgggccgggc ggagacgcag acggcgaggg 13350

 tgccagcgag ggcgctggag acgccgcgga gggcgctgga gacgaggagg 13400

 aggcggtgca cgaggccggg ccgggcggtg ccgacggggc ggtggccgtg 13450

 accgatgggg gccccttccg gcccgaaggg gctggcggtc tcggggacat 13500

 gggggacacg acgcctgcgg aaccgcccac acccgagggc tctcccatcc 13550

 tcaagaggaa attgggggtg gatggagtgg aggaggagct cccgccagag 13600

 ccagagcccg agccggaacc agagctggag ccggagaaag ccgatgccga 13650

 gaatggggag aaggaagaag ttcccgagcc cacaccagag ccccccaaga 13700

 agcaagcacc tccctcaccc cctccaaaga aggaggaagc tggaggcgaa 13750

 ttctggggag aactggaggt gcagagggtg aagttcctga actacctgtc 13800

 ccggaacttt tacaccctgc ggttccttgc cctcttcttg gcatttgcca 13850

 tcaacttcat cttgctgttt tataaggtct cagactctcc accaggggag 13900

 gacgacatgg aaggctcagc tgctggggat gtgtcaggtg caggctctgg 13950

 tggcagctct ggctggggct tgggggccgg agaggaggca gagggcgatg 14000

 aggatgagaa catggtgtac tacttcctgg aggaaagcac aggctacatg 14050

 gaacccgccc tgcggtgtct gagcctcctg catacactgg tggcctttct 14100

 ctgcatcatt ggctataatt gtctcaaggt gcccctggta atctttaagc 14150

 gggagaagga gctggcccgg aagctggagt ttgatggcct gtacatcacg 14200

 gagcagcctg aggacgatga cgtgaagggg cagtgggacc gactggtgct 14250

 caacacgccg tctttcccta gcaactactg ggacaagttt gtcaagcgca 14300

 aggtcctgga caaacatggg gacatctacg ggcgggagcg gattgctgag 14350

 ctactgggca tggacctggc cacactagag atcacagccc acaatgagcg 14400

 caagcccaac ccgccgccag ggctgctgac ctggctcatg tccatcgatg 14450

 tcaagtacca gatctggaag ttcggggtca tcttcacaga caactccttc 14500

 ctgtacctgg gctggtatat ggtgatgtcc ctcttgggac actacaacaa 14550

 cttcttcttt gctgcccatc tcctggacat cgccatgggg gtcaagacgc 14600

 tgcgcaccat cctgtcctct gtcacccaca atgggaaaca gctggtgatg 14650

 accgtgggcc ttctggcggt ggtcgtctac ctgtacaccg tggtggcctt 14700

 caacttcttc cgcaagttct acaacaagag cgaggatgag gatgaacctg 14750

 acatgaagtg tgatgacatg atgacgtgtt acctgtttca catgtacgtg 14800

 ggtgtccggg ctggcggagg cattggggac gagatcgagg accccgcggg 14850

 tgacgaatac gagctctaca gggtggtctt cgacatcacc ttcttcttct 14900

 tcgtcatcgt catcctgttg gccatcatcc agggtctgat catcgacgct 14950

 tttggtgagc tccgagacca acaagagcaa gtgaaggagg atatggagac 15000

 caagtgcttc atctgtggaa tcggcagtga ctactttgat acgacaccgc 15050

 atggcttcga gactcacacg ctggaggagc acaacctggc caattacatg 15100

 tttttcctga tgtatttgat aaacaaggat gagacagaac acacgggtca 15150

 ggagtcttat gtctggaaga tgtaccaaga gagatgttgg gatttcttcc 15200

 cagctggtga ttgtttccgt aagcagtatg aggaccagct tagctgacac 15250

 acccccagct ggccctccac ccccacctca agtgccttat tctcacagca 15300

 agccccttag tccccaagcc cctcccccta aggcagctgg gggagaggtg 15350

 acctagtac 15359

<210> 1368
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1368
 Met Gly Asp Ala Glu Gly Glu Asp Glu Val Gln Phe Leu Arg Thr
   1               5                  10                  15

 Asp Asp Glu Val Val Leu Gln Cys Ser Ala Thr Val Leu Lys Glu
                  20                  25                  30

 Gln Leu Lys Leu Cys Leu Ala Ala Glu Gly Phe Gly Asn Arg Leu
                  35                  40                  45

 Cys Phe Leu Glu Pro Thr Ser Asn Ala Gln Asn Val Pro Pro Asp
                  50                  55                  60

 Leu Ala Ile Cys Cys Phe Val Leu Glu Gln Ser Leu Ser Val Arg
                  65                  70                  75

 Ala Leu Gln Glu Met Leu Ala Asn Thr Val Glu Ala Gly Val Glu
                  80                  85                  90

 Ser Ser Gln Gly Gly Gly His Arg Thr Leu Leu Tyr Gly His Ala
                  95                 100                 105

 Ile Leu Leu Arg His Ala His Ser Arg Met Tyr Leu Ser Cys Leu
                 110                 115                 120

 Thr Thr Ser Arg Ser Met Thr Asp Lys Leu Ala Phe Asp Val Gly
                 125                 130                 135

 Leu Gln Glu Asp Ala Thr Gly Glu Ala Cys Trp Trp Thr Met His
                 140                 145                 150

 Pro Ala Ser Lys Gln Arg Ser Glu Gly Glu Lys Val Arg Val Gly
                 155                 160                 165

 Asp Asp Ile Ile Leu Val Ser Val Ser Ser Glu Arg Tyr Leu His
                 170                 175                 180

 Leu Ser Thr Ala Ser Gly Glu Leu Gln Val Asp Ala Ser Phe Met
                 185                 190                 195

 Gln Thr Leu Trp Asn Met Asn Pro Ile Cys Ser Arg Cys Glu Glu
                 200                 205                 210

 Gly Phe Val Thr Gly Gly His Val Leu Arg Leu Phe His Gly His
                 215                 220                 225

 Met Asp Glu Cys Leu Thr Ile Ser Pro Ala Asp Ser Asp Asp Gln
                 230                 235                 240

 Arg Arg Leu Val Tyr Tyr Glu Gly Gly Ala Val Cys Thr His Ala
                 245                 250                 255

 Arg Ser Leu Trp Arg Leu Glu Pro Leu Arg Ile Ser Trp Ser Gly
                 260                 265                 270

 Ser His Leu Arg Trp Gly Gln Pro Leu Arg Val Arg His Val Thr
                 275                 280                 285

 Thr Gly Gln Tyr Leu Ala Leu Thr Glu Asp Gln Gly Leu Val Val
                 290                 295                 300

 Val Asp Ala Ser Lys Ala His Thr Lys Ala Thr Ser Phe Cys Phe
                 305                 310                 315

 Arg Ile Ser Lys Glu Lys Leu Asp Val Ala Pro Lys Arg Asp Val
                 320                 325                 330

 Glu Gly Met Gly Pro Pro Glu Ile Lys Tyr Gly Glu Ser Leu Cys
                 335                 340                 345

 Phe Val Gln His Val Ala Ser Gly Leu Trp Leu Thr Tyr Ala Ala
                 350                 355                 360

 Pro Asp Pro Lys Ala Leu Arg Leu Gly Val Leu Lys Lys Lys Ala
                 365                 370                 375

 Met Leu His Gln Glu Gly His Met Asp Asp Ala Leu Ser Leu Thr
                 380                 385                 390

 Arg Cys Gln Gln Glu Glu Ser Gln Ala Ala Arg Met Ile His Ser
                 395                 400                 405

 Thr Asn Gly Leu Tyr Asn Gln Phe Ile Lys Ser Leu Asp Ser Phe
                 410                 415                 420

 Ser Gly Lys Pro Arg Gly Ser Gly Pro Pro Ala Gly Thr Ala Leu
                 425                 430                 435

 Pro Ile Glu Gly Val Ile Leu Ser Leu Gln Asp Leu Ile Ile Tyr
                 440                 445                 450

 Phe Glu Pro Pro Ser Glu Asp Leu Gln His Glu Glu Lys Gln Ser
                 455                 460                 465

 Lys Leu Arg Ser Leu Arg Asn Arg Gln Ser Leu Phe Gln Glu Glu
                 470                 475                 480

 Gly Met Leu Ser Met Val Leu Asn Cys Ile Asp Arg Leu Asn Val
                 485                 490                 495

 Tyr Thr Thr Ala Ala His Phe Ala Glu Phe Ala Gly Glu Glu Ala
                 500                 505                 510

 Ala Glu Ser Trp Lys Glu Ile Val Asn Leu Leu Tyr Glu Leu Leu
                 515                 520                 525

 Ala Ser Leu Ile Arg Gly Asn Arg Ser Asn Cys Ala Leu Phe Ser
                 530                 535                 540

 Thr Asn Leu Asp Trp Leu Val Ser Lys Leu Asp Arg Leu Glu Ala
                 545                 550                 555

 Ser Ser Gly Ile Leu Glu Val Leu Tyr Cys Val Leu Ile Glu Ser
                 560                 565                 570

 Pro Glu Val Leu Asn Ile Ile Gln Glu Asn His Ile Lys Ser Ile
                 575                 580                 585

 Ile Ser Leu Leu Asp Lys His Gly Arg Asn His Lys Val Leu Asp
                 590                 595                 600

 Val Leu Cys Ser Leu Cys Val Cys Asn Gly Val Ala Val Arg Ser
                 605                 610                 615

 Asn Gln Asp Leu Ile Thr Glu Asn Leu Leu Pro Gly Arg Glu Leu
                 620                 625                 630

 Leu Leu Gln Thr Asn Leu Ile Asn Tyr Val Thr Ser Ile Arg Pro
                 635                 640                 645

 Asn Ile Phe Val Gly Arg Ala Glu Gly Thr Thr Gln Tyr Ser Lys
                 650                 655                 660

 Trp Tyr Phe Glu Val Met Val Asp Glu Val Thr Pro Phe Leu Thr
                 665                 670                 675

 Ala Gln Ala Thr His Leu Arg Val Gly Trp Ala Leu Thr Glu Gly
                 680                 685                 690

 Tyr Thr Pro Tyr Pro Gly Ala Gly Glu Gly Trp Gly Gly Asn Gly
                 695                 700                 705

 Val Gly Asp Asp Leu Tyr Ser Tyr Gly Phe Asp Gly Leu His Leu
                 710                 715                 720

 Trp Thr Gly His Val Ala Arg Pro Val Thr Ser Pro Gly Gln His
                 725                 730                 735

 Leu Leu Ala Pro Glu Asp Val Ile Ser Cys Cys Leu Asp Leu Ser
                 740                 745                 750

 Val Pro Ser Ile Ser Phe Arg Ile Asn Gly Cys Pro Val Gln Gly
                 755                 760                 765

 Val Phe Glu Ser Phe Asn Leu Asp Gly Leu Phe Phe Pro Val Val
                 770                 775                 780

 Ser Phe Ser Ala Gly Val Lys Val Arg Phe Leu Leu Gly Gly Arg
                 785                 790                 795

 His Gly Glu Phe Lys Phe Leu Pro Pro Pro Gly Tyr Ala Pro Cys
                 800                 805                 810

 His Glu Ala Val Leu Pro Arg Glu Arg Leu His Leu Glu Pro Ile
                 815                 820                 825

 Lys Glu Tyr Arg Arg Glu Gly Pro Arg Gly Pro His Leu Val Gly
                 830                 835                 840

 Pro Ser Arg Cys Leu Ser His Thr Asp Phe Val Pro Cys Pro Val
                 845                 850                 855

 Asp Thr Val Gln Ile Val Leu Pro Pro His Leu Glu Arg Ile Arg
                 860                 865                 870

 Glu Lys Leu Ala Glu Asn Ile His Glu Leu Trp Ala Leu Thr Arg
                 875                 880                 885

 Ile Glu Gln Gly Trp Thr Tyr Gly Pro Val Arg Asp Asp Asn Lys
                 890                 895                 900

 Arg Leu His Pro Cys Leu Val Asp Phe His Ser Leu Pro Glu Pro
                 905                 910                 915

 Glu Arg Asn Tyr Asn Leu Gln Met Ser Gly Glu Thr Leu Lys Thr
                 920                 925                 930

 Leu Leu Ala Leu Gly Cys His Val Gly Met Ala Asp Glu Lys Ala
                 935                 940                 945

 Glu Asp Asn Leu Lys Lys Thr Lys Leu Pro Lys Thr Tyr Met Met
                 950                 955                 960

 Ser Asn Gly Tyr Lys Pro Ala Pro Leu Asp Leu Ser His Val Arg
                 965                 970                 975

 Leu Thr Pro Ala Gln Thr Thr Leu Val Asp Arg Leu Ala Glu Asn
                 980                 985                 990

 Gly His Asn Val Trp Ala Arg Asp Arg Val Gly Gln Gly Trp Ser
                 995                1000                1005

 Tyr Ser Ala Val Gln Asp Ile Pro Ala Arg Arg Asn Pro Arg Leu
                1010                1015                1020

 Val Pro Tyr Arg Leu Leu Asp Glu Ala Thr Lys Arg Ser Asn Arg
                1025                1030                1035

 Asp Ser Leu Cys Gln Ala Val Arg Thr Leu Leu Gly Tyr Gly Tyr
                1040                1045                1050

 Asn Ile Glu Pro Pro Asp Gln Glu Pro Ser Gln Val Glu Asn Gln
                1055                1060                1065

 Ser Arg Cys Asp Arg Val Arg Ile Phe Arg Ala Glu Lys Ser Tyr
                1070                1075                1080

 Thr Val Gln Ser Gly Arg Trp Tyr Phe Glu Phe Glu Ala Val Thr
                1085                1090                1095

 Thr Gly Glu Met Arg Val Gly Trp Ala Arg Pro Glu Leu Arg Pro
                1100                1105                1110

 Asp Val Glu Leu Gly Ala Asp Glu Leu Ala Tyr Val Phe Asn Gly
                1115                1120                1125

 His Arg Gly Gln Arg Trp His Leu Gly Ser Glu Pro Phe Gly Arg
                1130                1135                1140

 Pro Trp Gln Pro Gly Asp Val Val Gly Cys Met Ile Asp Leu Thr
                1145                1150                1155

 Glu Asn Thr Ile Ile Phe Thr Leu Asn Gly Glu Val Leu Met Ser
                1160                1165                1170

 Asp Ser Gly Ser Glu Thr Ala Phe Arg Glu Ile Glu Ile Gly Asp
                1175                1180                1185

 Gly Phe Leu Pro Val Cys Ser Leu Gly Pro Gly Gln Val Gly His
                1190                1195                1200

 Leu Asn Leu Gly Gln Asp Val Ser Ser Leu Arg Phe Phe Ala Ile
                1205                1210                1215

 Cys Gly Leu Gln Glu Gly Phe Glu Pro Phe Ala Ile Asn Met Gln
                1220                1225                1230

 Arg Pro Val Thr Thr Trp Phe Ser Lys Gly Leu Pro Gln Phe Glu
                1235                1240                1245

 Pro Val Pro Leu Glu His Pro His Tyr Glu Val Ser Arg Val Asp
                1250                1255                1260

 Gly Thr Val Asp Thr Pro Pro Cys Leu Arg Leu Thr His Arg Thr
                1265                1270                1275

 Trp Gly Ser Gln Asn Ser Leu Val Glu Met Leu Phe Leu Arg Leu
                1280                1285                1290

 Ser Leu Pro Val Gln Phe His Gln His Phe Arg Cys Thr Ala Gly
                1295                1300                1305

 Ala Thr Pro Leu Ala Pro Pro Gly Leu Gln Pro Pro Ala Glu Asp
                1310                1315                1320

 Glu Ala Arg Ala Ala Glu Pro Asp Pro Asp Tyr Glu Asn Leu Arg
                1325                1330                1335

 Arg Ser Ala Gly Gly Trp Ser Glu Ala Glu Asn Gly Lys Glu Gly
                1340                1345                1350

 Thr Ala Lys Glu Gly Ala Pro Gly Gly Thr Pro Gln Ala Gly Gly
                1355                1360                1365

 Glu Ala Gln Pro Ala Arg Ala Glu Asn Glu Lys Asp Ala Thr Thr
                1370                1375                1380

 Glu Lys Asn Lys Lys Arg Gly Phe Leu Phe Lys Ala Lys Lys Val
                1385                1390                1395

 Ala Met Met Thr Gln Pro Pro Ala Thr Pro Thr Leu Pro Arg Leu
                1400                1405                1410

 Pro His Asp Val Val Pro Ala Asp Asn Arg Asp Asp Pro Glu Ile
                1415                1420                1425

 Ile Leu Asn Thr Thr Thr Tyr Tyr Tyr Ser Val Arg Val Phe Ala
                1430                1435                1440

 Gly Gln Glu Pro Ser Cys Val Trp Ala Gly Trp Val Thr Pro Asp
                1445                1450                1455

 Tyr His Gln His Asp Met Ser Phe Asp Leu Ser Lys Val Arg Val
                1460                1465                1470

 Val Thr Val Thr Met Gly Asp Glu Gln Gly Asn Val His Ser Ser
                1475                1480                1485

 Leu Lys Cys Ser Asn Cys Tyr Met Val Trp Gly Gly Asp Phe Val
                1490                1495                1500

 Ser Pro Gly Gln Gln Gly Arg Ile Ser His Thr Asp Leu Val Ile
                1505                1510                1515

 Gly Cys Leu Val Asp Leu Ala Thr Gly Leu Met Thr Phe Thr Ala
                1520                1525                1530

 Asn Gly Lys Glu Ser Asn Thr Phe Phe Gln Val Glu Pro Asn Thr
                1535                1540                1545

 Lys Leu Phe Pro Ala Val Phe Val Leu Pro Thr His Gln Asn Val
                1550                1555                1560

 Ile Gln Phe Glu Leu Gly Lys Gln Lys Asn Ile Met Pro Leu Ser
                1565                1570                1575

 Ala Ala Met Phe Gln Ser Glu Arg Lys Asn Pro Ala Pro Gln Cys
                1580                1585                1590

 Pro Pro Arg Leu Glu Met Gln Met Leu Met Pro Val Ser Trp Ser
                1595                1600                1605

 Arg Met Pro Asn His Phe Leu Gln Val Glu Thr Arg Arg Ala Gly
                1610                1615                1620

 Glu Arg Leu Gly Trp Ala Val Gln Cys Gln Glu Pro Leu Thr Met
                1625                1630                1635

 Met Ala Leu His Ile Pro Glu Glu Asn Arg Cys Met Asp Ile Leu
                1640                1645                1650

 Glu Leu Ser Glu Arg Leu Asp Leu Gln Arg Phe His Ser His Thr
                1655                1660                1665

 Leu Arg Leu Tyr Arg Ala Val Cys Ala Leu Gly Asn Asn Arg Val
                1670                1675                1680

 Ala His Ala Leu Cys Ser His Val Asp Gln Ala Gln Leu Leu His
                1685                1690                1695

 Ala Leu Glu Asp Ala His Leu Pro Gly Pro Leu Arg Ala Gly Tyr
                1700                1705                1710

 Tyr Asp Leu Leu Ile Ser Ile His Leu Glu Ser Ala Cys Arg Ser
                1715                1720                1725

 Arg Arg Ser Met Leu Ser Glu Tyr Ile Val Pro Leu Thr Pro Glu
                1730                1735                1740

 Thr Arg Ala Ile Thr Leu Phe Pro Pro Gly Arg Ser Thr Glu Asn
                1745                1750                1755

 Gly His Pro Arg His Gly Leu Pro Gly Val Gly Val Thr Thr Ser
                1760                1765                1770

 Leu Arg Pro Pro His His Phe Ser Pro Pro Cys Phe Val Ala Ala
                1775                1780                1785

 Leu Pro Ala Ala Gly Ala Ala Glu Ala Pro Ala Arg Leu Ser Pro
                1790                1795                1800

 Ala Ile Pro Leu Glu Ala Leu Arg Asp Lys Ala Leu Arg Met Leu
                1805                1810                1815

 Gly Glu Ala Val Arg Asp Gly Gly Gln His Ala Arg Asp Pro Val
                1820                1825                1830

 Gly Ala Ser Val Glu Phe Gln Phe Val Pro Val Leu Lys Leu Val
                1835                1840                1845

 Ser Thr Leu Leu Val Met Gly Ile Phe Gly Asp Glu Asp Val Lys
                1850                1855                1860

 Gln Ile Leu Lys Met Ile Glu Pro Glu Val Phe Thr Glu Glu Glu
                1865                1870                1875

 Glu Glu Glu Asp Glu Glu Glu Glu Gly Glu Glu Glu Asp Glu Glu
                1880                1885                1890

 Glu Lys Glu Glu Asp Glu Glu Glu Thr Ala Gln Glu Lys Glu Asp
                1895                1900                1905

 Glu Glu Lys Glu Glu Glu Glu Ala Ala Glu Gly Glu Lys Glu Glu
                1910                1915                1920

 Gly Leu Glu Glu Gly Leu Leu Gln Met Lys Leu Pro Glu Ser Val
                1925                1930                1935

 Lys Leu Gln Met Cys His Leu Leu Glu Tyr Phe Cys Asp Gln Glu
                1940                1945                1950

 Leu Gln His Arg Val Glu Ser Leu Ala Ala Phe Ala Glu Arg Tyr
                1955                1960                1965

 Val Asp Lys Leu Gln Ala Asn Gln Arg Ser Arg Tyr Gly Leu Leu
                1970                1975                1980

 Ile Lys Ala Phe Ser Met Thr Ala Ala Glu Thr Ala Arg Arg Thr
                1985                1990                1995

 Arg Glu Phe Arg Ser
                2000

<210> 1369
<211> 878
<212> DNA
<213> Homo sapien

<400> 1369
 cagattttca ggttgattga tgtgggacag cagccacaat gaggaactcc 50

 tatagatttc tggcatcctc tctctcagtt gtcgtttctc tcctgctaat 100

 tcctgaagat gtctgtgaaa aaattattgg aggaaatgaa gtaactcctc 150

 attcaagacc ctacatggtc ctacttagtc ttgacagaaa aaccatctgt 200

 gctggggctt tgattgcaaa agactgggtg ttgactgcag ctcactgtaa 250

 cttgaacaaa aggtcccagg tcattcttgg ggctcactca ataaccaggg 300

 aagagccaac aaaacagata atgcttgtta agaaagagtt tccctatcca 350

 tgctatgacc cagccacacg cgaaggtgac cttaaacttt tacagctgac 400

 ggaaaaagca aaaattaaca aatatgtgac tatccttcat ctacctaaaa 450

 agggggatga tgtgaaacca ggaaccatgt gccaagttgc agggtggggg 500

 aggactcaca atagtgcatc ttggtccgat actctgagag aagtcaatat 550

 caccatcata gacagaaaag tctgcaatga tcgaaatcac tataatttta 600

 accctgtgat tggaatgaat atggtttgtg ctggaagcct ccgaggtgga 650

 agagactcgt gcaatggaga ttctggaagc cctttgttgt gcgagggtgt 700

 tttccgaggg gtcacttcct ttggccttga aaataaatgc ggagaccctc 750

 gtgggcctgg tgtctatatt cttctctcaa agaaacacct caactggata 800

 attatgacta tcaagggagc agtttaaata accgtttcct ttcatttact 850

 gtggcttctt aatcttttca caaataaa 878

<210> 1370
<211> 262
<212> PRT
<213> Homo sapien

<400> 1370
 Met Arg Asn Ser Tyr Arg Phe Leu Ala Ser Ser Leu Ser Val Val
   1               5                  10                  15

 Val Ser Leu Leu Leu Ile Pro Glu Asp Val Cys Glu Lys Ile Ile
                  20                  25                  30

 Gly Gly Asn Glu Val Thr Pro His Ser Arg Pro Tyr Met Val Leu
                  35                  40                  45

 Leu Ser Leu Asp Arg Lys Thr Ile Cys Ala Gly Ala Leu Ile Ala
                  50                  55                  60

 Lys Asp Trp Val Leu Thr Ala Ala His Cys Asn Leu Asn Lys Arg
                  65                  70                  75

 Ser Gln Val Ile Leu Gly Ala His Ser Ile Thr Arg Glu Glu Pro
                  80                  85                  90

 Thr Lys Gln Ile Met Leu Val Lys Lys Glu Phe Pro Tyr Pro Cys
                  95                 100                 105

 Tyr Asp Pro Ala Thr Arg Glu Gly Asp Leu Lys Leu Leu Gln Leu
                 110                 115                 120

 Thr Glu Lys Ala Lys Ile Asn Lys Tyr Val Thr Ile Leu His Leu
                 125                 130                 135

 Pro Lys Lys Gly Asp Asp Val Lys Pro Gly Thr Met Cys Gln Val
                 140                 145                 150

 Ala Gly Trp Gly Arg Thr His Asn Ser Ala Ser Trp Ser Asp Thr
                 155                 160                 165

 Leu Arg Glu Val Asn Ile Thr Ile Ile Asp Arg Lys Val Cys Asn
                 170                 175                 180

 Asp Arg Asn His Tyr Asn Phe Asn Pro Val Ile Gly Met Asn Met
                 185                 190                 195

 Val Cys Ala Gly Ser Leu Arg Gly Gly Arg Asp Ser Cys Asn Gly
                 200                 205                 210

 Asp Ser Gly Ser Pro Leu Leu Cys Glu Gly Val Phe Arg Gly Val
                 215                 220                 225

 Thr Ser Phe Gly Leu Glu Asn Lys Cys Gly Asp Pro Arg Gly Pro
                 230                 235                 240

 Gly Val Tyr Ile Leu Leu Ser Lys Lys His Leu Asn Trp Ile Ile
                 245                 250                 255

 Met Thr Ile Lys Gly Ala Val
                 260

<210> 1371
<211> 738
<212> DNA
<213> Homo sapien

<400> 1371
 gtatctgtgg taaacccagt gacacggggg agatgacata caaaaagggc 50

 aggacctgag aaagattaag ctgcaggctc cctgcccata aaacagggtg 100

 tgaaaggcat ctcagcggct gccccaccat ggctacctgg gccctcctgc 150

 tccttgcagc catgctcctg ggcaacccag gtctggtctt ctctcgtctg 200

 agccctgagt actacgacct ggcaagagcc cacctgcgtg atgaggagaa 250

 atcctgcccg tgcctggccc aggagggccc ccagggtgac ctgttgacca 300

 aaacacagga gctgggccgt gactacagga cctgtctgac gatagtccaa 350

 aaactgaaga agatggtgga taagcccacc cagagaagtg tttccaatgc 400

 tgcgacccgg gtgtgtagga cggggaggtc acgatggcgc gacgtctgca 450

 gaaatttcat gaggaggtat cagtctagag ttacccaggg cctcgtggcc 500

 ggagaaactg cccagcagat ctgtgaggac ctcaggttgt gtataccttc 550

 tacaggtccc ctctgagccc tctcaccttg tcctgtggaa gaagcacagg 600

 ctcctgtcct cagatcccgg gaacctcagc aacctctgcc ggctcctcgc 650

 ttcctcgatc cagaatccac tctccagtct ccctcccctg actccctctg 700

 ctgtcctccc ctctcacgag aataaagtgt caagcaag 738

<210> 1372
<211> 145
<212> PRT
<213> Homo sapien

<400> 1372
 Met Ala Thr Trp Ala Leu Leu Leu Leu Ala Ala Met Leu Leu Gly
   1               5                  10                  15

 Asn Pro Gly Leu Val Phe Ser Arg Leu Ser Pro Glu Tyr Tyr Asp
                  20                  25                  30

 Leu Ala Arg Ala His Leu Arg Asp Glu Glu Lys Ser Cys Pro Cys
                  35                  40                  45

 Leu Ala Gln Glu Gly Pro Gln Gly Asp Leu Leu Thr Lys Thr Gln
                  50                  55                  60

 Glu Leu Gly Arg Asp Tyr Arg Thr Cys Leu Thr Ile Val Gln Lys
                  65                  70                  75

 Leu Lys Lys Met Val Asp Lys Pro Thr Gln Arg Ser Val Ser Asn
                  80                  85                  90

 Ala Ala Thr Arg Val Cys Arg Thr Gly Arg Ser Arg Trp Arg Asp
                  95                 100                 105

 Val Cys Arg Asn Phe Met Arg Arg Tyr Gln Ser Arg Val Thr Gln
                 110                 115                 120

 Gly Leu Val Ala Gly Glu Thr Ala Gln Gln Ile Cys Glu Asp Leu
                 125                 130                 135

 Arg Leu Cys Ile Pro Ser Thr Gly Pro Leu
                 140                 145

<210> 1373
<211> 3959
<212> DNA
<213> Homo sapien

<400> 1373
 gcggctccgc cgccgcgaag gacagccttt ccgcgcggga ctccggggcg 50

 ccacgggggc catgtaagca gctatcttcc agagggccac actgggcatg 100

 gacacccttt tccctgcctg gaggagcaca ggtgatagtg taattttcca 150

 gtcacgaaac tgctaaggcc atctcagggg cgtgtgcgca ggataggcag 200

 gcggcgtccg aggaccacat agccatgcct tttggtctga agctccgccg 250

 gacacggcgc tacaacgtcc tgagcaagaa ctgctttgtc acacggattc 300

 gcctgctgga cagcaatgtt atcgagtgca cgctgtcggt ggaaagcaca 350

 gggcaagaat gcctggaggc tgtggcccag aggctggagc tgcgagagac 400

 gcactacttt ggcctttggt ttctcagcaa gagccagcaa gcacgatggg 450

 tggagctgga gaaacctctg aagaaacatc tggacaaatt cgctaatgag 500

 cctttgcttt tctttggagt catgttctat gtgccaaatg tgtcatggct 550

 tcagcaagag gccacaagat atcagtatta cctgcaagtc aaaaaagatg 600

 tgcttgaagg gcgattacga tgtacattgg accaggtgat tcggctagcc 650

 ggcctagctg tgcaagctga ttttggagac tataatcagt ttgattctca 700

 agatttcctc agagagtatg tgctatttcc tatggatttg gccctggaag 750

 aggctgttct ggaggagctg acccagaagg tagcccaaga acacaaagcc 800

 cacagtggaa tcctgccagc agaagctgaa ctgatgtaca tcaatgaagt 850

 tgaacgtttg gatggatttg gacaggaaat cttccctgta aaggacaatc 900

 atggaaactg tgtacacctt ggcattttct ttatggggat tttcgtgagg 950

 aacagaattg gaagacaagc ggtaatatac aggtggaatg acatggggaa 1000

 tatcactcat aacaagtcga ccattctagt ggagctcatc aacaaagaag 1050

 agactgccct ctttcacacg gatgatatcg aaaatgccaa gtatatttct 1100

 cggttgtttg ccacacgaca caagttttac aaacaaaaca aaatctgcac 1150

 tgaacagtca aattctccac cccccatcag acgccagccc acctggagcc 1200

 gatcctctct gcccaggcag cagccgtaca tcctgcctcc cgttcacgtc 1250

 cagtgtggtg agcactactc ggaaacgcac acctcgcaag acagcatttt 1300

 tcatgggaat gaagaagcct tgtattgcaa ctctcacaac agcctggact 1350

 taaattattt aaatggcact gtcaccaatg gcagcgtgtg tagcgttgac 1400

 agcgtcaact ccctcaactg ctcgcaaagt ttcatccagg cctcccctgt 1450

 atcctccaac ctcagtatcc ctgggagtga catcatgcgg gccgactaca 1500

 tcccgagcca ccggcacagc gcgatcatcg tgccctcgta caggccaacc 1550

 cccgattatg agacagtcat gcgccagatg aagaggggga tcctgcatac 1600

 agacagccag agccagtctc tgagaaacct caacattatc aacacccatg 1650

 cctacaacca gccagaggat ctggtgtaca gccaaccgga gatgcgggag 1700

 aggcacccct acactgtccc ttatgggcca cagggggtct acagcaacaa 1750

 acttgtcagt ccatctgacc agaggaaccc aaagaataat gtggtaccaa 1800

 gcaagccggg ggcaagcgcc atctcgcaca cggtgagcac cccagagctg 1850

 gccaacatgc agctgcaggg cagccataac tacagcacgg cccacatgct 1900

 taagaactat ctcttcaggc caccgccccc ctacccacgg ccacgacctg 1950

 ccaccagcac cccagacctg gccagccacc gccacaagta cgtcagcggc 2000

 agcagcccgg acctggtgac ccggaaggtg cagctctcgg tgaagacctt 2050

 ccaagaggac agctctccgg tggttcatca gtctctccag gaggtgagcg 2100

 agcccctcac ggccaccaag caccacggca ctgtgaacaa gcgccacagc 2150

 ctggaggtga tgaacagcat ggtgcggggc atggaggcca tgacgctcaa 2200

 gtcgctccac ctccccatgg ctcgccgcaa cacgctccgg gagcagggac 2250

 cgcccgagga ggggtcaggc agccacgagg tcccccagct ccctcagtat 2300

 caccacaaga agaccttctc tgatgccact atgctaatcc acagcagcga 2350

 gagtgaggag gaggaggagg aggctccaga atcggtgccc cagatcccca 2400

 tgctccggga gaagatggag tacagtgccc agctgcaggc ggccctggcc 2450

 cgcatcccca acaagccccc gcctgagtac cccggtccaa ggaagagtgt 2500

 gagcaatggg gctctgaggc aggaccaagc cagccttcct cccgccatgg 2550

 ccagagccag ggtgctgagg catgggccag ccaaggccat cagcatgtct 2600

 cggactgacc cgccggctgt caacggggcc tctctcggcc catccatctc 2650

 ggaacccgac ctgactagtg tgaaggagcg ggtcaaaaaa gagcctgtga 2700

 aggagagacc tgtgtctgaa atgttttccc tggaagacag cattatagag 2750

 agagagatga tgatcaggaa tctagagaag cagaagatgg caggcctgga 2800

 ggcacagaag aggccgctga tgttggcagc attgaatggg ctctcggtgg 2850

 ctcgagtctc agggcgggaa gagaatcgag ttgatgccac ccgggttccc 2900

 atggacgaga ggttcagaac cctgaagaag aaactagaag agggaatggt 2950

 gttcacagaa tatgagcaaa ttccaaagaa aaaggcgaat ggcattttca 3000

 gcacagcagc tctgccagaa aacgccgagc gcagccgaat ccgtgaagtt 3050

 gtcccctatg aggagaatcg agtagagctg ataccaacca aagaaaataa 3100

 cacaggatac attaatgcct cccacatcaa ggtggtggtt ggcggggcag 3150

 aatggcacta catagccacc caggggcccc tgccacacac gtgccacgac 3200

 ttctggcaga tggtgtggga gcagggagtg aatgtgattg ccatggtcac 3250

 tgcagaggag gagggtggac gaaccaaaag ccaccgatac tggcccaaac 3300

 taggttcaaa gcacagctca gccacctatg gcaagttcaa ggtcaccacg 3350

 aagtttcgaa cggattctgt ttgctatgca accacgggct tgaaggtcaa 3400

 gcaccttttg tctgggcaag aaaggacggt gtggcattta caatatactg 3450

 actggccaga tcacggctgt ccagaagatg tccaaggatt tttatcctac 3500

 ttggaggaga tccagtcggt ccgtcgccat accaacagca tgctggaagg 3550

 caccaagaac cggcacccgc ccatcgtggt ccactgtagt gctggggtgg 3600

 gaaggaccgg cgtgctcatt ctttctgagc tgatgatcta ctgcttggaa 3650

 cataacgaaa aggtggaagt gcccatgatg ctgaggctcc tcagggagca 3700

 gaggatgttc atgatccaga ctatcgctca gtacaagttt gtctaccaag 3750

 tcctcatcca gttcctccaa aactccagac tcatttaatc accccaatcc 3800

 agctcctgga ggagggaccc agctccatcg cgctggagga gagtcacctc 3850

 cagacaacat ctgctccccc cacaggggtg caggtggctg gcagcaaaca 3900

 ggctctctga agacagtagc caagattatt cacacatacc atgtattatt 3950

 ttatatgag 3959

<210> 1374
<211> 1187
<212> PRT
<213> Homo sapien

<400> 1374
 Met Pro Phe Gly Leu Lys Leu Arg Arg Thr Arg Arg Tyr Asn Val
   1               5                  10                  15

 Leu Ser Lys Asn Cys Phe Val Thr Arg Ile Arg Leu Leu Asp Ser
                  20                  25                  30

 Asn Val Ile Glu Cys Thr Leu Ser Val Glu Ser Thr Gly Gln Glu
                  35                  40                  45

 Cys Leu Glu Ala Val Ala Gln Arg Leu Glu Leu Arg Glu Thr His
                  50                  55                  60

 Tyr Phe Gly Leu Trp Phe Leu Ser Lys Ser Gln Gln Ala Arg Trp
                  65                  70                  75

 Val Glu Leu Glu Lys Pro Leu Lys Lys His Leu Asp Lys Phe Ala
                  80                  85                  90

 Asn Glu Pro Leu Leu Phe Phe Gly Val Met Phe Tyr Val Pro Asn
                  95                 100                 105

 Val Ser Trp Leu Gln Gln Glu Ala Thr Arg Tyr Gln Tyr Tyr Leu
                 110                 115                 120

 Gln Val Lys Lys Asp Val Leu Glu Gly Arg Leu Arg Cys Thr Leu
                 125                 130                 135

 Asp Gln Val Ile Arg Leu Ala Gly Leu Ala Val Gln Ala Asp Phe
                 140                 145                 150

 Gly Asp Tyr Asn Gln Phe Asp Ser Gln Asp Phe Leu Arg Glu Tyr
                 155                 160                 165

 Val Leu Phe Pro Met Asp Leu Ala Leu Glu Glu Ala Val Leu Glu
                 170                 175                 180

 Glu Leu Thr Gln Lys Val Ala Gln Glu His Lys Ala His Ser Gly
                 185                 190                 195

 Ile Leu Pro Ala Glu Ala Glu Leu Met Tyr Ile Asn Glu Val Glu
                 200                 205                 210

 Arg Leu Asp Gly Phe Gly Gln Glu Ile Phe Pro Val Lys Asp Asn
                 215                 220                 225

 His Gly Asn Cys Val His Leu Gly Ile Phe Phe Met Gly Ile Phe
                 230                 235                 240

 Val Arg Asn Arg Ile Gly Arg Gln Ala Val Ile Tyr Arg Trp Asn
                 245                 250                 255

 Asp Met Gly Asn Ile Thr His Asn Lys Ser Thr Ile Leu Val Glu
                 260                 265                 270

 Leu Ile Asn Lys Glu Glu Thr Ala Leu Phe His Thr Asp Asp Ile
                 275                 280                 285

 Glu Asn Ala Lys Tyr Ile Ser Arg Leu Phe Ala Thr Arg His Lys
                 290                 295                 300

 Phe Tyr Lys Gln Asn Lys Ile Cys Thr Glu Gln Ser Asn Ser Pro
                 305                 310                 315

 Pro Pro Ile Arg Arg Gln Pro Thr Trp Ser Arg Ser Ser Leu Pro
                 320                 325                 330

 Arg Gln Gln Pro Tyr Ile Leu Pro Pro Val His Val Gln Cys Gly
                 335                 340                 345

 Glu His Tyr Ser Glu Thr His Thr Ser Gln Asp Ser Ile Phe His
                 350                 355                 360

 Gly Asn Glu Glu Ala Leu Tyr Cys Asn Ser His Asn Ser Leu Asp
                 365                 370                 375

 Leu Asn Tyr Leu Asn Gly Thr Val Thr Asn Gly Ser Val Cys Ser
                 380                 385                 390

 Val Asp Ser Val Asn Ser Leu Asn Cys Ser Gln Ser Phe Ile Gln
                 395                 400                 405

 Ala Ser Pro Val Ser Ser Asn Leu Ser Ile Pro Gly Ser Asp Ile
                 410                 415                 420

 Met Arg Ala Asp Tyr Ile Pro Ser His Arg His Ser Ala Ile Ile
                 425                 430                 435

 Val Pro Ser Tyr Arg Pro Thr Pro Asp Tyr Glu Thr Val Met Arg
                 440                 445                 450

 Gln Met Lys Arg Gly Ile Leu His Thr Asp Ser Gln Ser Gln Ser
                 455                 460                 465

 Leu Arg Asn Leu Asn Ile Ile Asn Thr His Ala Tyr Asn Gln Pro
                 470                 475                 480

 Glu Asp Leu Val Tyr Ser Gln Pro Glu Met Arg Glu Arg His Pro
                 485                 490                 495

 Tyr Thr Val Pro Tyr Gly Pro Gln Gly Val Tyr Ser Asn Lys Leu
                 500                 505                 510

 Val Ser Pro Ser Asp Gln Arg Asn Pro Lys Asn Asn Val Val Pro
                 515                 520                 525

 Ser Lys Pro Gly Ala Ser Ala Ile Ser His Thr Val Ser Thr Pro
                 530                 535                 540

 Glu Leu Ala Asn Met Gln Leu Gln Gly Ser His Asn Tyr Ser Thr
                 545                 550                 555

 Ala His Met Leu Lys Asn Tyr Leu Phe Arg Pro Pro Pro Pro Tyr
                 560                 565                 570

 Pro Arg Pro Arg Pro Ala Thr Ser Thr Pro Asp Leu Ala Ser His
                 575                 580                 585

 Arg His Lys Tyr Val Ser Gly Ser Ser Pro Asp Leu Val Thr Arg
                 590                 595                 600

 Lys Val Gln Leu Ser Val Lys Thr Phe Gln Glu Asp Ser Ser Pro
                 605                 610                 615

 Val Val His Gln Ser Leu Gln Glu Val Ser Glu Pro Leu Thr Ala
                 620                 625                 630

 Thr Lys His His Gly Thr Val Asn Lys Arg His Ser Leu Glu Val
                 635                 640                 645

 Met Asn Ser Met Val Arg Gly Met Glu Ala Met Thr Leu Lys Ser
                 650                 655                 660

 Leu His Leu Pro Met Ala Arg Arg Asn Thr Leu Arg Glu Gln Gly
                 665                 670                 675

 Pro Pro Glu Glu Gly Ser Gly Ser His Glu Val Pro Gln Leu Pro
                 680                 685                 690

 Gln Tyr His His Lys Lys Thr Phe Ser Asp Ala Thr Met Leu Ile
                 695                 700                 705

 His Ser Ser Glu Ser Glu Glu Glu Glu Glu Glu Ala Pro Glu Ser
                 710                 715                 720

 Val Pro Gln Ile Pro Met Leu Arg Glu Lys Met Glu Tyr Ser Ala
                 725                 730                 735

 Gln Leu Gln Ala Ala Leu Ala Arg Ile Pro Asn Lys Pro Pro Pro
                 740                 745                 750

 Glu Tyr Pro Gly Pro Arg Lys Ser Val Ser Asn Gly Ala Leu Arg
                 755                 760                 765

 Gln Asp Gln Ala Ser Leu Pro Pro Ala Met Ala Arg Ala Arg Val
                 770                 775                 780

 Leu Arg His Gly Pro Ala Lys Ala Ile Ser Met Ser Arg Thr Asp
                 785                 790                 795

 Pro Pro Ala Val Asn Gly Ala Ser Leu Gly Pro Ser Ile Ser Glu
                 800                 805                 810

 Pro Asp Leu Thr Ser Val Lys Glu Arg Val Lys Lys Glu Pro Val
                 815                 820                 825

 Lys Glu Arg Pro Val Ser Glu Met Phe Ser Leu Glu Asp Ser Ile
                 830                 835                 840

 Ile Glu Arg Glu Met Met Ile Arg Asn Leu Glu Lys Gln Lys Met
                 845                 850                 855

 Ala Gly Leu Glu Ala Gln Lys Arg Pro Leu Met Leu Ala Ala Leu
                 860                 865                 870

 Asn Gly Leu Ser Val Ala Arg Val Ser Gly Arg Glu Glu Asn Arg
                 875                 880                 885

 Val Asp Ala Thr Arg Val Pro Met Asp Glu Arg Phe Arg Thr Leu
                 890                 895                 900

 Lys Lys Lys Leu Glu Glu Gly Met Val Phe Thr Glu Tyr Glu Gln
                 905                 910                 915

 Ile Pro Lys Lys Lys Ala Asn Gly Ile Phe Ser Thr Ala Ala Leu
                 920                 925                 930

 Pro Glu Asn Ala Glu Arg Ser Arg Ile Arg Glu Val Val Pro Tyr
                 935                 940                 945

 Glu Glu Asn Arg Val Glu Leu Ile Pro Thr Lys Glu Asn Asn Thr
                 950                 955                 960

 Gly Tyr Ile Asn Ala Ser His Ile Lys Val Val Val Gly Gly Ala
                 965                 970                 975

 Glu Trp His Tyr Ile Ala Thr Gln Gly Pro Leu Pro His Thr Cys
                 980                 985                 990

 His Asp Phe Trp Gln Met Val Trp Glu Gln Gly Val Asn Val Ile
                 995                1000                1005

 Ala Met Val Thr Ala Glu Glu Glu Gly Gly Arg Thr Lys Ser His
                1010                1015                1020

 Arg Tyr Trp Pro Lys Leu Gly Ser Lys His Ser Ser Ala Thr Tyr
                1025                1030                1035

 Gly Lys Phe Lys Val Thr Thr Lys Phe Arg Thr Asp Ser Val Cys
                1040                1045                1050

 Tyr Ala Thr Thr Gly Leu Lys Val Lys His Leu Leu Ser Gly Gln
                1055                1060                1065

 Glu Arg Thr Val Trp His Leu Gln Tyr Thr Asp Trp Pro Asp His
                1070                1075                1080

 Gly Cys Pro Glu Asp Val Gln Gly Phe Leu Ser Tyr Leu Glu Glu
                1085                1090                1095

 Ile Gln Ser Val Arg Arg His Thr Asn Ser Met Leu Glu Gly Thr
                1100                1105                1110

 Lys Asn Arg His Pro Pro Ile Val Val His Cys Ser Ala Gly Val
                1115                1120                1125

 Gly Arg Thr Gly Val Leu Ile Leu Ser Glu Leu Met Ile Tyr Cys
                1130                1135                1140

 Leu Glu His Asn Glu Lys Val Glu Val Pro Met Met Leu Arg Leu
                1145                1150                1155

 Leu Arg Glu Gln Arg Met Phe Met Ile Gln Thr Ile Ala Gln Tyr
                1160                1165                1170

 Lys Phe Val Tyr Gln Val Leu Ile Gln Phe Leu Gln Asn Ser Arg
                1175                1180                1185

 Leu Ile


<210> 1375
<211> 2107
<212> DNA
<213> Homo sapien

<400> 1375
 gtgaagtgct cagaatgggg caggatgtca cctggaatca gcactaagtg 50

 attcagactt tccttacttt taaatgtgct gctcttcatt tcaagatgcc 100

 gttgcagctc tgataaatgc aaactgacaa ccttcaaggc cacgacggag 150

 ggaaaatcat tggtgcttgg agcatagaag actgcccttc acaaaggaaa 200

 tccctgatta ttgtttgaaa tgctgaggac gttgctgcga aggagacttt 250

 tttcttatcc caccaaatac tactttatgg ttcttgtttt atccctaatc 300

 accttctccg ttttaaggat tcatcaaaag cctgaatttg taagtgtcag 350

 acacttggag cttgctgggg agaatcctag tagtgatatt aattgcacca 400

 aagttttaca gggtgatgta aatgaaatcc aaaaggtaaa gcttgagatc 450

 ctaacagtga aatttaaaaa gcgccctcgg tggacacctg acgactatat 500

 aaacatgacc agtgactgtt cttctttcat caagagacgc aaatatattg 550

 tagaacccct tagtaaagaa gaggcggagt ttccaatagc atattctata 600

 gtggttcatc acaagattga aatgcttgac aggctgctga gggccatcta 650

 tatgcctcag aatttctatt gcattcatgt ggacacaaaa tccgaggatt 700

 cctatttagc tgcagtgatg ggcatcgctt cctgttttag taatgtcttt 750

 gtggccagcc gattggagag tgtggtttat gcatcgtgga gccgggttca 800

 ggctgacctc aactgcatga aggatctcta tgcaatgagt gcaaactgga 850

 agtacttgat aaatctttgt ggtatggatt ttcccattaa aaccaaccta 900

 gaaattgtca ggaagctcaa gttgttaatg ggagaaaaca acctggaaac 950

 ggagaggatg ccatcccata aagaagaaag gtggaagaag cggtatgagg 1000

 tcgttaatgg aaagctgaca aacacaggga ctgtcaaaat gcttcctcca 1050

 ctcgaaacac ctctcttttc tggcagtgcc tacttcgtgg tcagtaggga 1100

 gtatgtgggg tatgtactac agaatgaaaa aatccaaaag ttgatggagt 1150

 gggcacaaga cacatacagc cctgatgagt atctctgggc caccatccaa 1200

 aggattcctg aagtcccggg ctcactccct gccagccata agtatgatct 1250

 gtctgacatg caagcagttg ccaggtttgt caagtggcag tactttgagg 1300

 gtgatgtttc caagggtgct ccctacccgc cctgcgatgg agtccatgtg 1350

 cgctcagtgt gcattttcgg agctggtgac ttgaactgga tgctgcgcaa 1400

 acaccacttg tttgccaata agtttgacgt ggatgttgac ctctttgcca 1450

 tccagtgttt ggatgagcat ttgagacaca aagctttgga gacattaaaa 1500

 cactgaccat tacgggcaat tttatgaaca agaagaagga tacacaaaac 1550

 gtacccttat ctgtttcccc ttccttgtca gcatcgggaa gatggtatga 1600

 agtcctcttt ggggcaggga ctctagtaga tcttcttgtc agagaagctg 1650

 catggtttct gcagagcaca gttagctaga aaggtgatag cattaaatgt 1700

 tcatctagag ttaatagtgg gaggagtaaa ggtagccttg aggccagagc 1750

 aggtagcaag gcattgtgga aagaggggac cagggtggct ggggaagagg 1800

 ccgatgcata aagtcagcct gttcaaagtg ctcagggact tagcaaaatg 1850

 agaagatgtg acctgtgcca aaactatttt gagaatttta aatgtgacca 1900

 tttttctggt atgaataaac ttacagcaac aaataatcaa agatacaatt 1950

 aatctgatat tatatttgtt gaaatagaaa tttgattgta ctataaatga 2000

 tttttgtaaa taatttatat tctgctctaa tactgtactg tgtagtgtgt 2050

 ctccgtatgt catctcaggg agcttaaaat gggcttgatt taacattgaa 2100

 aaaaaat 2107

<210> 1376
<211> 428
<212> PRT
<213> Homo sapien

<400> 1376
 Met Leu Arg Thr Leu Leu Arg Arg Arg Leu Phe Ser Tyr Pro Thr
   1               5                  10                  15

 Lys Tyr Tyr Phe Met Val Leu Val Leu Ser Leu Ile Thr Phe Ser
                  20                  25                  30

 Val Leu Arg Ile His Gln Lys Pro Glu Phe Val Ser Val Arg His
                  35                  40                  45

 Leu Glu Leu Ala Gly Glu Asn Pro Ser Ser Asp Ile Asn Cys Thr
                  50                  55                  60

 Lys Val Leu Gln Gly Asp Val Asn Glu Ile Gln Lys Val Lys Leu
                  65                  70                  75

 Glu Ile Leu Thr Val Lys Phe Lys Lys Arg Pro Arg Trp Thr Pro
                  80                  85                  90

 Asp Asp Tyr Ile Asn Met Thr Ser Asp Cys Ser Ser Phe Ile Lys
                  95                 100                 105

 Arg Arg Lys Tyr Ile Val Glu Pro Leu Ser Lys Glu Glu Ala Glu
                 110                 115                 120

 Phe Pro Ile Ala Tyr Ser Ile Val Val His His Lys Ile Glu Met
                 125                 130                 135

 Leu Asp Arg Leu Leu Arg Ala Ile Tyr Met Pro Gln Asn Phe Tyr
                 140                 145                 150

 Cys Ile His Val Asp Thr Lys Ser Glu Asp Ser Tyr Leu Ala Ala
                 155                 160                 165

 Val Met Gly Ile Ala Ser Cys Phe Ser Asn Val Phe Val Ala Ser
                 170                 175                 180

 Arg Leu Glu Ser Val Val Tyr Ala Ser Trp Ser Arg Val Gln Ala
                 185                 190                 195

 Asp Leu Asn Cys Met Lys Asp Leu Tyr Ala Met Ser Ala Asn Trp
                 200                 205                 210

 Lys Tyr Leu Ile Asn Leu Cys Gly Met Asp Phe Pro Ile Lys Thr
                 215                 220                 225

 Asn Leu Glu Ile Val Arg Lys Leu Lys Leu Leu Met Gly Glu Asn
                 230                 235                 240

 Asn Leu Glu Thr Glu Arg Met Pro Ser His Lys Glu Glu Arg Trp
                 245                 250                 255

 Lys Lys Arg Tyr Glu Val Val Asn Gly Lys Leu Thr Asn Thr Gly
                 260                 265                 270

 Thr Val Lys Met Leu Pro Pro Leu Glu Thr Pro Leu Phe Ser Gly
                 275                 280                 285

 Ser Ala Tyr Phe Val Val Ser Arg Glu Tyr Val Gly Tyr Val Leu
                 290                 295                 300

 Gln Asn Glu Lys Ile Gln Lys Leu Met Glu Trp Ala Gln Asp Thr
                 305                 310                 315

 Tyr Ser Pro Asp Glu Tyr Leu Trp Ala Thr Ile Gln Arg Ile Pro
                 320                 325                 330

 Glu Val Pro Gly Ser Leu Pro Ala Ser His Lys Tyr Asp Leu Ser
                 335                 340                 345

 Asp Met Gln Ala Val Ala Arg Phe Val Lys Trp Gln Tyr Phe Glu
                 350                 355                 360

 Gly Asp Val Ser Lys Gly Ala Pro Tyr Pro Pro Cys Asp Gly Val
                 365                 370                 375

 His Val Arg Ser Val Cys Ile Phe Gly Ala Gly Asp Leu Asn Trp
                 380                 385                 390

 Met Leu Arg Lys His His Leu Phe Ala Asn Lys Phe Asp Val Asp
                 395                 400                 405

 Val Asp Leu Phe Ala Ile Gln Cys Leu Asp Glu His Leu Arg His
                 410                 415                 420

 Lys Ala Leu Glu Thr Leu Lys His
                 425

<210> 1377
<211> 1461
<212> DNA
<213> Homo sapien

<400> 1377
 tttaaggcgc cgggtttccg gggctcctgg ccccgcttat tccgcggggg 50

 tcggcggggt cggcctgggc gcccgcgccg ccgctgcgct ttgtccgctg 100

 ggcacactgc ttctgggagg ggcgggcaga catggtggcg gccgccgccc 150

 cctcctcggc cctagcatgc cgcggccgcc tcgcggctac ccggcttgcc 200

 ggtcccgagc ggcagccccg gggtggcgat ggggtcgcgc cgaggcagcg 250

 gaggttctgc gggcgactgg aggttggcag tgggcgggag aaagaggaag 300

 gcaggcgcgg ctgggcctcg gcctctggcg ccgcggtacc ctttgtctcg 350

 gcagcctgac ggccccgccg ggctctccgg agaggggaac gggcggcgag 400

 ggtggcgggt cctgggcgcc ctgtgctgcg gggccgagag gcgctcgggt 450

 cgcggcggga ccggccggac cagacagggt taatggaaga gcctggccag 500

 tcccgcgcgg ggcccccgca gcgacagcct tggccgcggg gactggagtc 550

 ctgaggggga gaagcctgcc gttctgaagg ctcgggactt ctgccccaaa 600

 gacttcgccg ccgagaactg cgggtgcact gcctcaggga agaagttgag 650

 aattttgcca ggtcatctct gccagggcac agttcatcac tgtgtgttta 700

 gtgtgtttcg gtgaagctct ccaagtgtgt tgaatcagcg tgcctagcct 750

 caagggtgca tcgtgaaaac tgaaaccaaa ggaatgatac aggcctgctt 800

 tgtgtgtgtc ttcccacttt aagcttgttt tcagtacaaa tactcttgct 850

 ttaaacctga ttggactgtg gcgagcggac atctgttcaa aggaggggcc 900

 gagaccacag tacttctgaa gggggcttga taatgtggaa acattttaag 950

 ttttctctcc ggactgtttt gctctctcaa ttcaggcaag ttactgaagt 1000

 acgtttttta tctagaaaaa ggtttgatgt agtctgtaaa tggtccttgt 1050

 aaagtacatt gccatctcag aattaaaaga tccactctca tttattatgc 1100

 agaagttagt ggtcattctt tcctgtagat agtttatctc atgtaaagac 1150

 ccacccagct tggtttaaat ttttttctca ctgacgtata accatcagct 1200

 ttgatacttc cattttcagg ctcagacttt gaatttaagg aaactaaaga 1250

 tgactttatt ttcttttctc ttggtttttt tttccaaaaa caaaaaataa 1300

 atccattaca tgttaacata gatgataaga gtgacatctt gcatttttgc 1350

 aaatcttttt aatgcctggt ttaatagaag attctcagat ctacgtcaga 1400

 ctgttgtggt tagcacacca tgtaacctct ggaacactcc actgtacact 1450

 catacttttt t 1461

<210> 1378
<211> 136
<212> PRT
<213> Homo sapien

<400> 1378
 Met Pro Arg Pro Pro Arg Gly Tyr Pro Ala Cys Arg Ser Arg Ala
   1               5                  10                  15

 Ala Ala Pro Gly Trp Arg Trp Gly Arg Ala Glu Ala Ala Glu Val
                  20                  25                  30

 Leu Arg Ala Thr Gly Gly Trp Gln Trp Ala Gly Glu Arg Gly Arg
                  35                  40                  45

 Gln Ala Arg Leu Gly Leu Gly Leu Trp Arg Arg Gly Thr Leu Cys
                  50                  55                  60

 Leu Gly Ser Leu Thr Ala Pro Pro Gly Ser Pro Glu Arg Gly Thr
                  65                  70                  75

 Gly Gly Glu Gly Gly Gly Ser Trp Ala Pro Cys Ala Ala Gly Pro
                  80                  85                  90

 Arg Gly Ala Arg Val Ala Ala Gly Pro Ala Gly Pro Asp Arg Val
                  95                 100                 105

 Asn Gly Arg Ala Trp Pro Val Pro Arg Gly Ala Pro Ala Ala Thr
                 110                 115                 120

 Ala Leu Ala Ala Gly Thr Gly Val Leu Arg Gly Arg Ser Leu Pro
                 125                 130                 135

 Phe


<210> 1379
<211> 4521
<212> DNA
<213> Homo sapien

<400> 1379
 acttcattca cttgcaaatc agtgtgtgcc cacaagagcc agctctcccg 50

 agcccgtaac cttcgcatcc caagagctgc agtttcagcc gcgacagcaa 100

 gaacggcaga gccggcgacc gcggcggcgg cggcggcgga ggcaggagca 150

 gcctgggcgg gtcgcagggt ctccgcgggc gcaggaaggc gagcagagat 200

 atcctctgag agccaagcaa agaacattaa ggaaggaagg aggaatgagg 250

 ctggatacgg tgcagtgaaa aaggcacttc caagagtggg gcactcacta 300

 cgcacagact cgacggtgcc atcagcatga gaacttaccg ctacttcttg 350

 ctgctctttt gggtgggcca gccctaccca actctctcaa ctccactatc 400

 aaagaggact agtggtttcc cagcaaagaa aagggccctg gagctctctg 450

 gaaacagcaa aaatgagctg aaccgttcaa aaaggagctg gatgtggaat 500

 cagttctttc tcctggagga atacacagga tccgattatc agtatgtggg 550

 caagttacat tcagaccagg atagaggaga tggatcactt aaatatatcc 600

 tttcaggaga tggagcagga gatctcttca ttattaatga aaacacaggc 650

 gacatacagg ccaccaagag gctggacagg gaagaaaaac ccgtttacat 700

 ccttcgagct caagctataa acagaaggac agggagaccc gtggagcccg 750

 agtctgaatt catcatcaag atccatgaca tcaatgacaa tgaaccaata 800

 ttcaccaagg aggtttacac agccactgtc cctgaaatgt ctgatgtcgg 850

 tacatttgtt gtccaagtca ctgcgacgga tgcagatgat ccaacatatg 900

 ggaacagtgc taaagttgtc tacagtattc tacagggaca gccctatttt 950

 tcagttgaat cagaaacagg tattatcaag acagctttgc tcaacatgga 1000

 tcgagaaaac agggagcagt accaagtggt gattcaagcc aaggatatgg 1050

 gcggccagat gggaggatta tctgggacca ccaccgtgaa catcacactg 1100

 actgatgtca acgacaaccc tccccgattc ccccagagta cataccagtt 1150

 taaaactcct gaatcttctc caccggggac accaattggc agaatcaaag 1200

 ccagcgacgc tgatgtggga gaaaatgctg aaattgagta cagcatcaca 1250

 gacggtgagg ggctggatat gtttgatgtc atcaccgacc aggaaaccca 1300

 ggaagggatt ataactgtca aaaagctctt ggactttgaa aagaagaaag 1350

 tgtataccct taaagtggaa gcctccaatc cttatgttga gccacgattt 1400

 ctctacttgg ggcctttcaa agattcagcc acggttagaa ttgtggtgga 1450

 ggatgtagat gagccacctg tcttcagcaa actggcctac atcttacaaa 1500

 taagagaaga tgctcagata aacaccacaa taggctccgt cacagcccaa 1550

 gatccagatg ctgccaggaa tcctgtcaag tactctgtag atcgacacac 1600

 agatatggac agaatattca acattgattc tggaaatggt tcgattttta 1650

 catcgaaact tcttgaccga gaaacactgc tatggcacaa cattacagtg 1700

 atagcaacag agatcaataa tccaaagcaa agtagtcgag tacctctata 1750

 tattaaagtt ctagatgtca atgacaacgc cccagaattt gctgagttct 1800

 atgaaacttt tgtctgtgaa aaagcaaagg cagatcagtt gattcagacc 1850

 ctgcatgctg ttgacaagga tgacccttat agtggacacc aattttcgtt 1900

 ttccttggcc cctgaagcag ccagtggctc aaactttacc attcaagaca 1950

 acaaagacaa cacggcggga atcttaactc ggaaaaatgg ctataataga 2000

 cacgagatga gcacctatct cttgcctgtg gtcatttcag acaacgacta 2050

 cccagttcaa agcagcactg ggacagtgac tgtccgggtc tgtgcatgtg 2100

 accaccacgg gaacatgcaa tcctgccatg cggaggcgct catccacccc 2150

 acgggactga gcacgggggc tctggttgcc atccttctgt gcatcgtgat 2200

 cctactagtg acagtggtgc tgtttgcagc tctgaggcgg cagcgaaaaa 2250

 aagagccttt gatcatttcc aaagaggaca tcagagataa cattgtcagt 2300

 tacaacgacg aaggtggtgg agaggaggac acccaggctt ttgatatcgg 2350

 caccctgagg aatcctgaag ccatagagga caacaaatta cgaagggaca 2400

 ttgtgcccga agcccttttc ctaccccgac ggactccaac agctcgcgac 2450

 aacaccgatg tcagagattt cattaaccaa aggttaaagg aaaatgacac 2500

 ggaccccact gccccgccat acgactcctt ggccacttac gcctatgaag 2550

 gcactggctc cgtggcggat tccctgagct cgctggagtc agtgaccacg 2600

 gatgcagatc aagactatga ttaccttagt gactggggac ctcgattcaa 2650

 aaagcttgca gatatgtatg gaggagtgga cagtgacaaa gactcctaat 2700

 ctgttgcctt tttcattttc caatacgaca ctgaaatatg tgaagtggct 2750

 atttctttat atttatccac tactccgtga aggcttctct gttctacccg 2800

 ttccaaaagc caatggctgc agtccgtgtg gatccaatgt tagagacttt 2850

 tttctagtac acttttatga gcttccaagg ggcaaatttt tattttttag 2900

 tgcatccagt taaccaagtc agcccaacag gcaggtgccg gaggggagga 2950

 cagggaacag tatttccact tgttctcagg gcagcgtgcc cgcttccgct 3000

 gtcctggtgt tttactacac tccatgtcag gtcagccaac tgccctaact 3050

 gtacatttca caggctaatg ggataaagga ctgtgcttta aagataaaaa 3100

 tatcatcata gtaaaagaaa tgagggcata tcggctcaca aagagataaa 3150

 ctacataggg gtgtttattt gtgtcacaaa gaatttaaaa taacacttgc 3200

 ccatgctatt tgttcttcaa gaactttctc tgccatcaac tactattcaa 3250

 aacctcaaat ccacccatat gttaaaattc tcattactct taaggaatag 3300

 aagcaaatta aacggtaaca tccaaaagca accacaaacc tagtacgact 3350

 tcattccttc cactaactca tagtttgtta tatcctagac tagacatgcg 3400

 aaagtttgcc tttgtaccat ataaaggggg agggaaatag ctaataatgt 3450

 taaccaagga aatatatttt accatacatt taaagttttg gccaccacat 3500

 gtatcacggg tcacttgaaa ttctttcagc tatcagtagg ctaatgtcaa 3550

 aattgtttaa aaattcttga aagaattttc ctgagacaaa ttttaacttc 3600

 ttgtctatag ttgtcagtat tattctacta tactgtacat gaaagtagca 3650

 gtgtgaagta caataattca tattcttcat atccttctta cacgactaag 3700

 ttgaattagt aaagttagat taaataaaac ttaaatctca ctctaggagt 3750

 tcagtggaga ggttagagcc agccacactt gaacctaata ccctgccctt 3800

 gacatctgga aacctctaca tatttatata acgtgataca tttggataaa 3850

 caacattgag attatgatga aaacctacat attccatgtt tggaagaccc 3900

 ttggaagagg aaaattggat tcccttaaac aaaagtgttt aagattgtaa 3950

 ttaaaatgat agttgatttt caaaagcatt aatttttttt cattgttttt 4000

 aactttgctt tcatgaccat cctgccatcc ttgactttga actaatgata 4050

 aagtaatgat ctcaaactat gacagaaaag taatgtaaaa tccatccaat 4100

 ctattatttc tctaattatg caattagcct catagttatt atccagagga 4150

 cccaactgaa ctgaactaat ccttctggca gattcaaatc gtttatttca 4200

 cacgctgttc taatggcact tatcattaga atcttacctt gtgcagtcat 4250

 cagaaattcc agcgtactat aatgaaaaca tccttgtttt gaaaacctaa 4300

 aagacaggct ctgtatatat atatacttaa gaatatgctg acttcactta 4350

 ttagtcttag ggatttattt tcaattaata ttaattttct acaaataatt 4400

 ttagtgtcat ttccatttgg ggatattgtc atatcagcac atattttctg 4450

 tttggaaaca cactgttgtt tagttaagtt ttaaataggt gtattaccca 4500

 agaagtaaag atggaaacgt t 4521

<210> 1380
<211> 790
<212> PRT
<213> Homo sapien

<400> 1380
 Met Arg Thr Tyr Arg Tyr Phe Leu Leu Leu Phe Trp Val Gly Gln
   1               5                  10                  15

 Pro Tyr Pro Thr Leu Ser Thr Pro Leu Ser Lys Arg Thr Ser Gly
                  20                  25                  30

 Phe Pro Ala Lys Lys Arg Ala Leu Glu Leu Ser Gly Asn Ser Lys
                  35                  40                  45

 Asn Glu Leu Asn Arg Ser Lys Arg Ser Trp Met Trp Asn Gln Phe
                  50                  55                  60

 Phe Leu Leu Glu Glu Tyr Thr Gly Ser Asp Tyr Gln Tyr Val Gly
                  65                  70                  75

 Lys Leu His Ser Asp Gln Asp Arg Gly Asp Gly Ser Leu Lys Tyr
                  80                  85                  90

 Ile Leu Ser Gly Asp Gly Ala Gly Asp Leu Phe Ile Ile Asn Glu
                  95                 100                 105

 Asn Thr Gly Asp Ile Gln Ala Thr Lys Arg Leu Asp Arg Glu Glu
                 110                 115                 120

 Lys Pro Val Tyr Ile Leu Arg Ala Gln Ala Ile Asn Arg Arg Thr
                 125                 130                 135

 Gly Arg Pro Val Glu Pro Glu Ser Glu Phe Ile Ile Lys Ile His
                 140                 145                 150

 Asp Ile Asn Asp Asn Glu Pro Ile Phe Thr Lys Glu Val Tyr Thr
                 155                 160                 165

 Ala Thr Val Pro Glu Met Ser Asp Val Gly Thr Phe Val Val Gln
                 170                 175                 180

 Val Thr Ala Thr Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala
                 185                 190                 195

 Lys Val Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val
                 200                 205                 210

 Glu Ser Glu Thr Gly Ile Ile Lys Thr Ala Leu Leu Asn Met Asp
                 215                 220                 225

 Arg Glu Asn Arg Glu Gln Tyr Gln Val Val Ile Gln Ala Lys Asp
                 230                 235                 240

 Met Gly Gly Gln Met Gly Gly Leu Ser Gly Thr Thr Thr Val Asn
                 245                 250                 255

 Ile Thr Leu Thr Asp Val Asn Asp Asn Pro Pro Arg Phe Pro Gln
                 260                 265                 270

 Ser Thr Tyr Gln Phe Lys Thr Pro Glu Ser Ser Pro Pro Gly Thr
                 275                 280                 285

 Pro Ile Gly Arg Ile Lys Ala Ser Asp Ala Asp Val Gly Glu Asn
                 290                 295                 300

 Ala Glu Ile Glu Tyr Ser Ile Thr Asp Gly Glu Gly Leu Asp Met
                 305                 310                 315

 Phe Asp Val Ile Thr Asp Gln Glu Thr Gln Glu Gly Ile Ile Thr
                 320                 325                 330

 Val Lys Lys Leu Leu Asp Phe Glu Lys Lys Lys Val Tyr Thr Leu
                 335                 340                 345

 Lys Val Glu Ala Ser Asn Pro Tyr Val Glu Pro Arg Phe Leu Tyr
                 350                 355                 360

 Leu Gly Pro Phe Lys Asp Ser Ala Thr Val Arg Ile Val Val Glu
                 365                 370                 375

 Asp Val Asp Glu Pro Pro Val Phe Ser Lys Leu Ala Tyr Ile Leu
                 380                 385                 390

 Gln Ile Arg Glu Asp Ala Gln Ile Asn Thr Thr Ile Gly Ser Val
                 395                 400                 405

 Thr Ala Gln Asp Pro Asp Ala Ala Arg Asn Pro Val Lys Tyr Ser
                 410                 415                 420

 Val Asp Arg His Thr Asp Met Asp Arg Ile Phe Asn Ile Asp Ser
                 425                 430                 435

 Gly Asn Gly Ser Ile Phe Thr Ser Lys Leu Leu Asp Arg Glu Thr
                 440                 445                 450

 Leu Leu Trp His Asn Ile Thr Val Ile Ala Thr Glu Ile Asn Asn
                 455                 460                 465

 Pro Lys Gln Ser Ser Arg Val Pro Leu Tyr Ile Lys Val Leu Asp
                 470                 475                 480

 Val Asn Asp Asn Ala Pro Glu Phe Ala Glu Phe Tyr Glu Thr Phe
                 485                 490                 495

 Val Cys Glu Lys Ala Lys Ala Asp Gln Leu Ile Gln Thr Leu His
                 500                 505                 510

 Ala Val Asp Lys Asp Asp Pro Tyr Ser Gly His Gln Phe Ser Phe
                 515                 520                 525

 Ser Leu Ala Pro Glu Ala Ala Ser Gly Ser Asn Phe Thr Ile Gln
                 530                 535                 540

 Asp Asn Lys Asp Asn Thr Ala Gly Ile Leu Thr Arg Lys Asn Gly
                 545                 550                 555

 Tyr Asn Arg His Glu Met Ser Thr Tyr Leu Leu Pro Val Val Ile
                 560                 565                 570

 Ser Asp Asn Asp Tyr Pro Val Gln Ser Ser Thr Gly Thr Val Thr
                 575                 580                 585

 Val Arg Val Cys Ala Cys Asp His His Gly Asn Met Gln Ser Cys
                 590                 595                 600

 His Ala Glu Ala Leu Ile His Pro Thr Gly Leu Ser Thr Gly Ala
                 605                 610                 615

 Leu Val Ala Ile Leu Leu Cys Ile Val Ile Leu Leu Val Thr Val
                 620                 625                 630

 Val Leu Phe Ala Ala Leu Arg Arg Gln Arg Lys Lys Glu Pro Leu
                 635                 640                 645

 Ile Ile Ser Lys Glu Asp Ile Arg Asp Asn Ile Val Ser Tyr Asn
                 650                 655                 660

 Asp Glu Gly Gly Gly Glu Glu Asp Thr Gln Ala Phe Asp Ile Gly
                 665                 670                 675

 Thr Leu Arg Asn Pro Glu Ala Ile Glu Asp Asn Lys Leu Arg Arg
                 680                 685                 690

 Asp Ile Val Pro Glu Ala Leu Phe Leu Pro Arg Arg Thr Pro Thr
                 695                 700                 705

 Ala Arg Asp Asn Thr Asp Val Arg Asp Phe Ile Asn Gln Arg Leu
                 710                 715                 720

 Lys Glu Asn Asp Thr Asp Pro Thr Ala Pro Pro Tyr Asp Ser Leu
                 725                 730                 735

 Ala Thr Tyr Ala Tyr Glu Gly Thr Gly Ser Val Ala Asp Ser Leu
                 740                 745                 750

 Ser Ser Leu Glu Ser Val Thr Thr Asp Ala Asp Gln Asp Tyr Asp
                 755                 760                 765

 Tyr Leu Ser Asp Trp Gly Pro Arg Phe Lys Lys Leu Ala Asp Met
                 770                 775                 780

 Tyr Gly Gly Val Asp Ser Asp Lys Asp Ser
                 785                 790

<210> 1381
<211> 1330
<212> DNA
<213> Homo sapien

<400> 1381
 gcggacgcgg ggcgccagca ggtggcgctg gacgcgcaac ggacaaggag 50

 gcggggcctg cagctggctt ggaggctccg cgctctggag gctcaggcgc 100

 cgcgtggggc ccgcacctct gggcagcagc ggcagccgag actcacggtc 150

 aagctaaggc gaagagtggg tggctgaagc catactattt tatagaatta 200

 atggaaagca gaaaagacat cacaaaccaa gaagaacttt ggaaaatgaa 250

 gcctaggaga aatttagaag aagacgatta tttgcataag gacacgggag 300

 agaccagcat gctaaaaaga cctgtgcttt tgcatttgca ccaaacagcc 350

 catgctgatg aatttgactg cccttcagaa cttcagcaca cacaggaact 400

 ctttccacag tggcacttgc caattaaaat agctgctatt atagcatctc 450

 tgacttttct ttacactctt ctgagggaag taattcaccc tttagcaact 500

 tcccatcaac aatattttta taaaattcca atcctggtca tcaacaaagt 550

 cttgccaatg gtttccatca ctctcttggc attggtttac ctgccaggtg 600

 tgatagcagc aattgtccaa cttcataatg gaaccaagta taagaagttt 650

 ccacattggt tggataagtg gatgttaaca agaaagcagt ttgggcttct 700

 cagtttcttt tttgctgtac tgcatgcaat ttatagtctg tcttacccaa 750

 tgaggcgatc ctacagatac aagttgctaa actgggcata tcaacaggtc 800

 caacaaaata aagaagatgc ctggattgag catgatgttt ggagaatgga 850

 gatttatgtg tctctgggaa ttgtgggatt ggcaatactg gctctgttgg 900

 ctgtgacatc tattccatct gtgagtgact ctttgacatg gagagaattt 950

 cactatattc agagcaagct aggaattgtt tcccttctac tgggcacaat 1000

 acacgcattg atttttgcct ggaataagtg gatagatata aaacaatttg 1050

 tatggtatac acctccaact tttatgatag ctgttttcct tccaattgtt 1100

 gtcctgatat ttaaaagcat actattcctg ccatgcttga ggaagaagat 1150

 actgaagatt agacatggtt gggaagacgt caccaaaatt aacaaaactg 1200

 agatatgttc ccagttgtag aattactgtt tacacacatt tttgttcaat 1250

 attgatatat tttatcacca acatttcaag tttgtatttg ttaataaaat 1300

 gattattcaa ggaaaaaaaa aaaaaaaaaa 1330

<210> 1382
<211> 339
<212> PRT
<213> Homo sapien

<400> 1382
 Met Glu Ser Arg Lys Asp Ile Thr Asn Gln Glu Glu Leu Trp Lys
   1               5                  10                  15

 Met Lys Pro Arg Arg Asn Leu Glu Glu Asp Asp Tyr Leu His Lys
                  20                  25                  30

 Asp Thr Gly Glu Thr Ser Met Leu Lys Arg Pro Val Leu Leu His
                  35                  40                  45

 Leu His Gln Thr Ala His Ala Asp Glu Phe Asp Cys Pro Ser Glu
                  50                  55                  60

 Leu Gln His Thr Gln Glu Leu Phe Pro Gln Trp His Leu Pro Ile
                  65                  70                  75

 Lys Ile Ala Ala Ile Ile Ala Ser Leu Thr Phe Leu Tyr Thr Leu
                  80                  85                  90

 Leu Arg Glu Val Ile His Pro Leu Ala Thr Ser His Gln Gln Tyr
                  95                 100                 105

 Phe Tyr Lys Ile Pro Ile Leu Val Ile Asn Lys Val Leu Pro Met
                 110                 115                 120

 Val Ser Ile Thr Leu Leu Ala Leu Val Tyr Leu Pro Gly Val Ile
                 125                 130                 135

 Ala Ala Ile Val Gln Leu His Asn Gly Thr Lys Tyr Lys Lys Phe
                 140                 145                 150

 Pro His Trp Leu Asp Lys Trp Met Leu Thr Arg Lys Gln Phe Gly
                 155                 160                 165

 Leu Leu Ser Phe Phe Phe Ala Val Leu His Ala Ile Tyr Ser Leu
                 170                 175                 180

 Ser Tyr Pro Met Arg Arg Ser Tyr Arg Tyr Lys Leu Leu Asn Trp
                 185                 190                 195

 Ala Tyr Gln Gln Val Gln Gln Asn Lys Glu Asp Ala Trp Ile Glu
                 200                 205                 210

 His Asp Val Trp Arg Met Glu Ile Tyr Val Ser Leu Gly Ile Val
                 215                 220                 225

 Gly Leu Ala Ile Leu Ala Leu Leu Ala Val Thr Ser Ile Pro Ser
                 230                 235                 240

 Val Ser Asp Ser Leu Thr Trp Arg Glu Phe His Tyr Ile Gln Ser
                 245                 250                 255

 Lys Leu Gly Ile Val Ser Leu Leu Leu Gly Thr Ile His Ala Leu
                 260                 265                 270

 Ile Phe Ala Trp Asn Lys Trp Ile Asp Ile Lys Gln Phe Val Trp
                 275                 280                 285

 Tyr Thr Pro Pro Thr Phe Met Ile Ala Val Phe Leu Pro Ile Val
                 290                 295                 300

 Val Leu Ile Phe Lys Ser Ile Leu Phe Leu Pro Cys Leu Arg Lys
                 305                 310                 315

 Lys Ile Leu Lys Ile Arg His Gly Trp Glu Asp Val Thr Lys Ile
                 320                 325                 330

 Asn Lys Thr Glu Ile Cys Ser Gln Leu
                 335

<210> 1383
<211> 1378
<212> DNA
<213> Homo sapien

<400> 1383
 cgacgcggga gccgcacgcg ccggacgagg ctcgctgcgc tccctgttgc 50

 ccagcgcggg cccgttgagg cggagccctc agttcccggc caggacacgg 100

 tctgggccgc cgaatctccg gccgaagagc ggcggcggca gcggcggaaa 150

 aaaatgaaga atgaaattgc tgccgttgtc ttctttttca caaggctagt 200

 tcgaaaacat gataagttga aaaaagaggc agttgagagg tttgctgaga 250

 aattgaccct aatacttcaa gaaaaatata aaaatcactg gtatccagaa 300

 aaaccatcga aaggacaggc ctacagatgt attcgtgtca ataaatttca 350

 gagagttgat cctgatgtcc tgaaagcctg tgaaaacagc tgcatcttgt 400

 atagtgacct gggcttgcca aaggagctca ctctctgggt ggacccatgt 450

 gaggtgtgct gtcggtatgg agagaaaaac aatgcattca ttgttgccag 500

 ctttgaaaat aaagatgaga acaaggatga gatctccagg aaagttacca 550

 gggcccttga taaggttacc tctgattatc attcaggatc ctcttcttca 600

 gatgaagaaa caagtaagga aatggaagtg aaacccagtt cggtgactgc 650

 agccgcaagt cctgtgtacc agatttcaga acttatattt ccacctcttc 700

 caatgtggca ccctttgccc agaaaaaagc caggaatgta tcgagggaat 750

 ggccatcaga atcactatcc tcctcctgtt ccatttggtt atccaaatca 800

 gggaagaaaa aataaaccat atcgcccaat tccagtgaca tgggtacctc 850

 ctcctggaat gcattgtgac cggaatcact ggattaatcc tcacatgtta 900

 gcacctcact aacttcgttt ttgattgtgt tggtgtcatg ttgagaaaaa 950

 ggtagaataa accttactac acattaaaag ttaaaagttc ttactaatag 1000

 tagtgaagtt agatgggcca aaccatcaaa cttattttta tagaagttat 1050

 tgagaataat ctttcttaaa aaatatatgc actttagata ttgatatagt 1100

 ttgagaaatt ttattaaagt tagtcaagtg cctaagtttt taatattgga 1150

 cttgagtatt tatatattgt gcatcaactc tgttggatac gagaacactg 1200

 tagaagtgga cgatttgttc tagcaccttt gagaatttac tttatggagc 1250

 gtatgtaagt tatttatata caaggaaatc tattttatgt cgttgtttaa 1300

 gagaattgtg tgaaatcatg tagttgcaaa taaaaaatag tttgaggcat 1350

 gaaaaaaaaa aaaaaaaaaa aaaaaaaa 1378

<210> 1384
<211> 252
<212> PRT
<213> Homo sapien

<400> 1384
 Met Lys Asn Glu Ile Ala Ala Val Val Phe Phe Phe Thr Arg Leu
   1               5                  10                  15

 Val Arg Lys His Asp Lys Leu Lys Lys Glu Ala Val Glu Arg Phe
                  20                  25                  30

 Ala Glu Lys Leu Thr Leu Ile Leu Gln Glu Lys Tyr Lys Asn His
                  35                  40                  45

 Trp Tyr Pro Glu Lys Pro Ser Lys Gly Gln Ala Tyr Arg Cys Ile
                  50                  55                  60

 Arg Val Asn Lys Phe Gln Arg Val Asp Pro Asp Val Leu Lys Ala
                  65                  70                  75

 Cys Glu Asn Ser Cys Ile Leu Tyr Ser Asp Leu Gly Leu Pro Lys
                  80                  85                  90

 Glu Leu Thr Leu Trp Val Asp Pro Cys Glu Val Cys Cys Arg Tyr
                  95                 100                 105

 Gly Glu Lys Asn Asn Ala Phe Ile Val Ala Ser Phe Glu Asn Lys
                 110                 115                 120

 Asp Glu Asn Lys Asp Glu Ile Ser Arg Lys Val Thr Arg Ala Leu
                 125                 130                 135

 Asp Lys Val Thr Ser Asp Tyr His Ser Gly Ser Ser Ser Ser Asp
                 140                 145                 150

 Glu Glu Thr Ser Lys Glu Met Glu Val Lys Pro Ser Ser Val Thr
                 155                 160                 165

 Ala Ala Ala Ser Pro Val Tyr Gln Ile Ser Glu Leu Ile Phe Pro
                 170                 175                 180

 Pro Leu Pro Met Trp His Pro Leu Pro Arg Lys Lys Pro Gly Met
                 185                 190                 195

 Tyr Arg Gly Asn Gly His Gln Asn His Tyr Pro Pro Pro Val Pro
                 200                 205                 210

 Phe Gly Tyr Pro Asn Gln Gly Arg Lys Asn Lys Pro Tyr Arg Pro
                 215                 220                 225

 Ile Pro Val Thr Trp Val Pro Pro Pro Gly Met His Cys Asp Arg
                 230                 235                 240

 Asn His Trp Ile Asn Pro His Met Leu Ala Pro His
                 245                 250

<210> 1385
<211> 1377
<212> DNA
<213> Homo sapien

<400> 1385
 aacgaaacca acagcagtcc aagctcagtc agcagaagag ataaaagcaa 50

 acaggtctgg gaggcagttc tgttgccact ctctctcctg tcaatgatgg 100

 atctcagaaa taccccagcc aaatctctgg acaagttcat tgaagactat 150

 ctcttgccag acacgtgttt ccgcatgcaa atcaaccatg ccattgacat 200

 catctgtggg ttcctgaagg aaaggtgctt ccgaggtagc tcctaccctg 250

 tgtgtgtgtc caaggtggta aagggtggct cctcaggcaa gggcaccacc 300

 ctcagaggcc gatctgacgc tgacctggtt gtcttcctca gtcctctcac 350

 cacttttcag gatcagttaa atcgccgggg agagttcatc caggaaatta 400

 ggagacagct ggaagcctgt caaagagaga gagcattttc cgtgaagttt 450

 gaggtccagg ctccacgctg gggcaacccc cgtgcgctca gcttcgtact 500

 gagttcgctc cagctcgggg agggggtgga gttcgatgtg ctgcctgcct 550

 ttgatgccct gggtcagttg actggcagct ataaacctaa cccccaaatc 600

 tatgtcaagc tcatcgagga gtgcaccgac ctgcagaaag agggcgagtt 650

 ctccacctgc ttcacagaac tacagagaga cttcctgaag cagcgcccca 700

 ccaagctcaa gagcctcatc cgcctagtca agcactggta ccaaaattgt 750

 aagaagaagc ttgggaagct gccacctcag tatgccctgg agctcctgac 800

 ggtctatgct tgggagcgag ggagcatgaa aacacatttc aacacagccc 850

 agggatttcg gacggtcttg gaattagtca taaactacca gcaactctgc 900

 atctactgga caaagtatta tgactttaaa aaccccatta ttgaaaagta 950

 cctgagaagg cagctcacga aacccacgcc tgtgatcctg gacccggcgg 1000

 accctacagg aaacttgggt ggtggagacc caaagcgttg gaggcagctg 1050

 gcacaagagg ctgaggcctg gctgaattac ccatgcttta agaattggga 1100

 tgggtcccca gtgagctcct ggattctgct ggtgagacct cctgcttcct 1150

 ccctgccatt catccctgcc cctctccatg aagcttgaga catatagctg 1200

 gagaccattc tttccaaaga acttacctct tgccaaaggc catttatatt 1250

 catatagtga caggctgtgc tccatatttt acagtcattt tggtcacaat 1300

 cgagggtttc tggaattttc acatcccttg tccagaattc attcccctaa 1350

 gagtaataat aaataatctc taacacc 1377

<210> 1386
<211> 364
<212> PRT
<213> Homo sapien

<400> 1386
 Met Met Asp Leu Arg Asn Thr Pro Ala Lys Ser Leu Asp Lys Phe
   1               5                  10                  15

 Ile Glu Asp Tyr Leu Leu Pro Asp Thr Cys Phe Arg Met Gln Ile
                  20                  25                  30

 Asn His Ala Ile Asp Ile Ile Cys Gly Phe Leu Lys Glu Arg Cys
                  35                  40                  45

 Phe Arg Gly Ser Ser Tyr Pro Val Cys Val Ser Lys Val Val Lys
                  50                  55                  60

 Gly Gly Ser Ser Gly Lys Gly Thr Thr Leu Arg Gly Arg Ser Asp
                  65                  70                  75

 Ala Asp Leu Val Val Phe Leu Ser Pro Leu Thr Thr Phe Gln Asp
                  80                  85                  90

 Gln Leu Asn Arg Arg Gly Glu Phe Ile Gln Glu Ile Arg Arg Gln
                  95                 100                 105

 Leu Glu Ala Cys Gln Arg Glu Arg Ala Phe Ser Val Lys Phe Glu
                 110                 115                 120

 Val Gln Ala Pro Arg Trp Gly Asn Pro Arg Ala Leu Ser Phe Val
                 125                 130                 135

 Leu Ser Ser Leu Gln Leu Gly Glu Gly Val Glu Phe Asp Val Leu
                 140                 145                 150

 Pro Ala Phe Asp Ala Leu Gly Gln Leu Thr Gly Ser Tyr Lys Pro
                 155                 160                 165

 Asn Pro Gln Ile Tyr Val Lys Leu Ile Glu Glu Cys Thr Asp Leu
                 170                 175                 180

 Gln Lys Glu Gly Glu Phe Ser Thr Cys Phe Thr Glu Leu Gln Arg
                 185                 190                 195

 Asp Phe Leu Lys Gln Arg Pro Thr Lys Leu Lys Ser Leu Ile Arg
                 200                 205                 210

 Leu Val Lys His Trp Tyr Gln Asn Cys Lys Lys Lys Leu Gly Lys
                 215                 220                 225

 Leu Pro Pro Gln Tyr Ala Leu Glu Leu Leu Thr Val Tyr Ala Trp
                 230                 235                 240

 Glu Arg Gly Ser Met Lys Thr His Phe Asn Thr Ala Gln Gly Phe
                 245                 250                 255

 Arg Thr Val Leu Glu Leu Val Ile Asn Tyr Gln Gln Leu Cys Ile
                 260                 265                 270

 Tyr Trp Thr Lys Tyr Tyr Asp Phe Lys Asn Pro Ile Ile Glu Lys
                 275                 280                 285

 Tyr Leu Arg Arg Gln Leu Thr Lys Pro Thr Pro Val Ile Leu Asp
                 290                 295                 300

 Pro Ala Asp Pro Thr Gly Asn Leu Gly Gly Gly Asp Pro Lys Arg
                 305                 310                 315

 Trp Arg Gln Leu Ala Gln Glu Ala Glu Ala Trp Leu Asn Tyr Pro
                 320                 325                 330

 Cys Phe Lys Asn Trp Asp Gly Ser Pro Val Ser Ser Trp Ile Leu
                 335                 340                 345

 Leu Val Arg Pro Pro Ala Ser Ser Leu Pro Phe Ile Pro Ala Pro
                 350                 355                 360

 Leu His Glu Ala


<210> 1387
<211> 3178
<212> DNA
<213> Homo sapien

<400> 1387
 ggcaccgatt cggggcctgc ccggacttcg ccgcacgctg cagaacctcg 50

 cccagcgccc accatgcccc ggcagctcag cgcggcggcc gcgctcttcg 100

 cgtccctggc cgtaattttg cacgatggca gtcaaatgag agcaaaagca 150

 tttccagaaa ccagagatta ttctcaacct actgcagcag caacagtaca 200

 ggacataaaa aaacctgtcc agcaaccagc taagcaagca cctcaccaaa 250

 ctttagcagc aagattcatg gatggtcata tcacctttca aacagcggcc 300

 acagtaaaaa ttccaacaac taccccagca actacaaaaa acactgcaac 350

 caccagccca attacctaca ccctggtcac aacccaggcc acacccaaca 400

 actcacacac agctcctcca gttactgaag ttacagtcgg ccctagctta 450

 gccccttatt cactgccacc caccatcacc ccaccagctc atacagctgg 500

 aaccagttca tcaaccgtca gccacacaac tgggaacacc actcaaccca 550

 gtaaccagac cacccttcca gcaactttat cgatagcact gcacaaaagc 600

 acaaccggtc agaagcctga tcaacccacc catgccccag gaacaacggc 650

 agctgcccac aataccaccc gcacagctgc acctgcctcc acggttcctg 700

 ggcccaccct tgcacctcag ccatcgtcag tcaagactgg aatttatcag 750

 gttctaaacg gaagcagact ctgtataaaa gcagagatgg ggatacagct 800

 gattgttcaa gacaaggagt cggttttttc acctcggaga tacttcaaca 850

 tcgaccccaa cgcaacgcaa gcctctggga actgtggcac ccgaaaatcc 900

 aaccttctgt tgaattttca gggcggattt gtgaatctca catttaccaa 950

 ggatgaagaa tcatattata tcagtgaagt gggagcctat ttgaccgtct 1000

 cagatccaga gacagtttac caaggaatca aacatgcggt ggtgatgttc 1050

 cagacagcag tcgggcattc cttcaagtgc gtgagtgaac agagcctcca 1100

 gttgtcagcc cacctgcagg tgaaaacaac cgatgtccaa cttcaagcct 1150

 ttgattttga agatgaccac tttggaaatg tggatgagtg ctcgtctgac 1200

 tacacaattg tgcttcctgt gattggggcc atcgtggttg gtctctgcct 1250

 tatgggtatg ggtgtctata aaatccgcct aaggtgtcaa tcatctggat 1300

 accagagaat ctaattgttg cccgggggga atgaaaataa tggaatttag 1350

 agaactcttt catcccttcc aggatggatg ttgggaaatt ccctcagagt 1400

 gtgggtcctt caaacaatgt aaaccaccat cttctattca aatgaagtga 1450

 gtcatgtgtg atttaagttc aggcagcaca tcaatttcta aatacttttt 1500

 gtttatttta tgaaagatat agtgagctgt ttattttcta gtttccttta 1550

 gaatatttta gccactcaaa gtcaacattt gagatatgtt gaattaacat 1600

 aatatatgta aagtagaata agccttcaaa ttataaacca agggtcaatt 1650

 gtaactaata ctactgtgtg tgcattgaag attttatttt acccttgatc 1700

 ttaacaaagc ctttgctttg ttatcaaatg gactttcagt gcttttacta 1750

 tctgtgtttt atggtttcat gtaacataca tattcctggt gtagcactta 1800

 actccttttc cactttaaat ttgtttttgt tttttgagac ggagtttcac 1850

 tcttgtcacc caggctggag tacagtggca cgatctcggc ttatggcaac 1900

 ctccgcctcc cgggttcaag tgattctcct gcttcagctt cccgagtagc 1950

 tgggattaca ggcacacact accacgcctg gctaattttt gtatttttat 2000

 tatagacggg tttcaccatg ttggccagac tggtcttgaa ctcttgacct 2050

 caggtgatcc acccacctca gcctcccaaa gtgctgggat tacaggcatg 2100

 agccattgcg cccggcctta aatgtttttt ttaatcatca aaaagaacaa 2150

 catatctcag gttgtctaag tgtttttatg taaaaccaac aaaaagaaca 2200

 aatcagctta tattttttat cttgatgact cctgctccag aattgctaga 2250

 ctaagaatta ggtggctaca gatggtagaa ctaaacaata agcaagagac 2300

 aataataatg gcccttaatt attaacaaag tgccagagtc taggctaagc 2350

 actttatcta tatctcattt cattctcaca acttataagt gaatgagtaa 2400

 actgagactt aagggaactg aatcacttaa atgtcacctg gctaactgat 2450

 ggcagagcca gagcttgaat tcatgttggt ctgacatcaa ggtctttggt 2500

 cttctcccta caccaagtta cctacaagaa caatgacacc acactctgcc 2550

 tgaaggctca cacctcatac cagcatacgc tcaccttaca gggaaatggg 2600

 tttatccagg atcatgagac attagggtag atgaaaggag agctttgcag 2650

 ataacaaaat agcctatcct taataaatcc tccactctct ggaaggagac 2700

 tgaggggctt tgtaaaacat tagtcagttg ctcattttta tgggattgct 2750

 tagctgggct gtaaagatga aggcatcaaa taaactcaaa gtatttttaa 2800

 atttttttga taatagagaa acttcgctaa ccaactgttc tttcttgagt 2850

 gtatagcccc atcttgtggt aacttgctgc ttctgcactt catatccata 2900

 tttcctattg ttcactttat tctgtagagc agcctgccaa gaattttatt 2950

 tctgctgttt tttttgctgc taaagaaagg aactaagtca ggatgttaac 3000

 agaaaagtcc acataaccct agaattctta gtcaaggaat aattcaagtc 3050

 agcctagaga ccatgttgac tttcctcatg tgtttcctta tgactcagta 3100

 agttggcaag gtcctgactt tagtcttaat aaaacattga attgtagtaa 3150

 aggtttttgc aataaaaact tactttgg 3178

<210> 1388
<211> 416
<212> PRT
<213> Homo sapien

<400> 1388
 Met Pro Arg Gln Leu Ser Ala Ala Ala Ala Leu Phe Ala Ser Leu
   1               5                  10                  15

 Ala Val Ile Leu His Asp Gly Ser Gln Met Arg Ala Lys Ala Phe
                  20                  25                  30

 Pro Glu Thr Arg Asp Tyr Ser Gln Pro Thr Ala Ala Ala Thr Val
                  35                  40                  45

 Gln Asp Ile Lys Lys Pro Val Gln Gln Pro Ala Lys Gln Ala Pro
                  50                  55                  60

 His Gln Thr Leu Ala Ala Arg Phe Met Asp Gly His Ile Thr Phe
                  65                  70                  75

 Gln Thr Ala Ala Thr Val Lys Ile Pro Thr Thr Thr Pro Ala Thr
                  80                  85                  90

 Thr Lys Asn Thr Ala Thr Thr Ser Pro Ile Thr Tyr Thr Leu Val
                  95                 100                 105

 Thr Thr Gln Ala Thr Pro Asn Asn Ser His Thr Ala Pro Pro Val
                 110                 115                 120

 Thr Glu Val Thr Val Gly Pro Ser Leu Ala Pro Tyr Ser Leu Pro
                 125                 130                 135

 Pro Thr Ile Thr Pro Pro Ala His Thr Ala Gly Thr Ser Ser Ser
                 140                 145                 150

 Thr Val Ser His Thr Thr Gly Asn Thr Thr Gln Pro Ser Asn Gln
                 155                 160                 165

 Thr Thr Leu Pro Ala Thr Leu Ser Ile Ala Leu His Lys Ser Thr
                 170                 175                 180

 Thr Gly Gln Lys Pro Asp Gln Pro Thr His Ala Pro Gly Thr Thr
                 185                 190                 195

 Ala Ala Ala His Asn Thr Thr Arg Thr Ala Ala Pro Ala Ser Thr
                 200                 205                 210

 Val Pro Gly Pro Thr Leu Ala Pro Gln Pro Ser Ser Val Lys Thr
                 215                 220                 225

 Gly Ile Tyr Gln Val Leu Asn Gly Ser Arg Leu Cys Ile Lys Ala
                 230                 235                 240

 Glu Met Gly Ile Gln Leu Ile Val Gln Asp Lys Glu Ser Val Phe
                 245                 250                 255

 Ser Pro Arg Arg Tyr Phe Asn Ile Asp Pro Asn Ala Thr Gln Ala
                 260                 265                 270

 Ser Gly Asn Cys Gly Thr Arg Lys Ser Asn Leu Leu Leu Asn Phe
                 275                 280                 285

 Gln Gly Gly Phe Val Asn Leu Thr Phe Thr Lys Asp Glu Glu Ser
                 290                 295                 300

 Tyr Tyr Ile Ser Glu Val Gly Ala Tyr Leu Thr Val Ser Asp Pro
                 305                 310                 315

 Glu Thr Val Tyr Gln Gly Ile Lys His Ala Val Val Met Phe Gln
                 320                 325                 330

 Thr Ala Val Gly His Ser Phe Lys Cys Val Ser Glu Gln Ser Leu
                 335                 340                 345

 Gln Leu Ser Ala His Leu Gln Val Lys Thr Thr Asp Val Gln Leu
                 350                 355                 360

 Gln Ala Phe Asp Phe Glu Asp Asp His Phe Gly Asn Val Asp Glu
                 365                 370                 375

 Cys Ser Ser Asp Tyr Thr Ile Val Leu Pro Val Ile Gly Ala Ile
                 380                 385                 390

 Val Val Gly Leu Cys Leu Met Gly Met Gly Val Tyr Lys Ile Arg
                 395                 400                 405

 Leu Arg Cys Gln Ser Ser Gly Tyr Gln Arg Ile
                 410                 415

<210> 1389
<211> 3870
<212> DNA
<213> Homo sapien

<400> 1389
 cagggagaca tacaggattt aagaagccca tcatggagaa gaccttcaat 50

 tacagagata aaaagttttt cttgtggaac aagttaacac tagatggcag 100

 ataacagact gaggagtgag ctgcttctga ctcgattaaa aagggagtga 150

 gccataactg gcggctgctc tttcgccaat gagcctcccc aattcctcct 200

 gcctcttaga agacaagatg tgtgagggca acaagaccac tatggccagc 250

 ccccagctga tgcccctggt ggtggtcctg agcactatct gcttggtcac 300

 agtagggctc aacctgctgg tgctgtatgc cgtacggagt gagcggaagc 350

 tccacactgt ggggaacctg tacatcgtca gcctctcggt ggcggacttg 400

 atcgtgggtg ccgtcgtcat gcctatgaac atcctctacc tgctcatgtc 450

 caagtggtca ctgggccgtc ctctctgcct cttttggctt tccatggact 500

 atgtggccag cacagcgtcc attttcagtg tcttcatcct gtgcattgat 550

 cgctaccgct ctgtccagca gcccctcagg taccttaagt atcgtaccaa 600

 gacccgagcc tcggccacca ttctgggggc ctggtttctc tcttttctgt 650

 gggttattcc cattctaggc tggaatcact tcatgcagca gacctcggtg 700

 cgccgagagg acaagtgtga gacagacttc tatgatgtca cctggttcaa 750

 ggtcatgact gccatcatca acttctacct gcccaccttg ctcatgctct 800

 ggttctatgc caagatctac aaggccgtac gacaacactg ccagcaccgg 850

 gagctcatca ataggtccct cccttccttc tcagaaatta agctgaggcc 900

 agagaacccc aagggggatg ccaagaaacc agggaaggag tctccctggg 950

 aggttctgaa aaggaagcca aaagatgctg gtggtggatc tgtcttgaag 1000

 tcaccatccc aaacccccaa ggagatgaaa tccccagttg tcttcagcca 1050

 agaggatgat agagaagtag acaaactcta ctgctttcca cttgatattg 1100

 tgcacatgca ggctgcggca gaggggagta gcagggacta tgtagccgtc 1150

 aaccggagcc atggccagct caagacagat gagcagggcc tgaacacaca 1200

 tggggccagc gagatatcag aggatcagat gttaggtgat agccaatcct 1250

 tctctcgaac ggactcagat accaccacag agacagcacc aggcaaaggc 1300

 aaattgagga gtgggtctaa cacaggcctg gattacatca agtttacttg 1350

 gaagaggctc cgctcgcatt caagacagta tgtatctggg ttgcacatga 1400

 accgcgaaag gaaggccgcc aaacagttgg gttttatcat ggcagccttc 1450

 atcctctgct ggatccctta tttcatcttc ttcatggtca ttgccttctg 1500

 caagaactgt tgcaatgaac atttgcacat gttcaccatc tggctgggct 1550

 acatcaactc cacactgaac cccctcatct accccttgtg caatgagaac 1600

 ttcaagaaga cattcaagag aattctgcat attcgctcct aagggaggct 1650

 ctgaggggat gcaacaaaat gatccttatg atgtccaaca aggaaataga 1700

 ggacgaaggc ctgtgtgttg ccaggcaggc acctgggctt tctggaatcc 1750

 aaaccacagt cttaggggct tggtagtttg gaaagttctt aggcaccata 1800

 gaagaacagc agatggcggt gatcagcaga gagattgaac tttgaggagg 1850

 aagcagaatc tttgcaagaa agtcagacct gtttcttgta actgggttca 1900

 aaaagaaaaa aataataaaa ataaaagaga gagagaatca gacctgggtg 1950

 gaactctcct gctcctcagg aactatggga gcctcagact cattgtaatt 2000

 caagctttcc gagtcaagtg attgacaact gaagagacac gtggctaggg 2050

 ttccactgga gaattgaaaa ggactcttga gccctcctgg aatggagctg 2100

 tataactgtg cagagacttt atccatgcca atagttgctg tccccttcca 2150

 ggggtcacct tgagaggcat gacagctgtt ccacaggggc tatcccttct 2200

 cagaaaactt ctcttctgag cctctttaac agctttctcc agaaccagtg 2250

 tctgaaccac cctggaaatt ctgccttatt atttcttact caaacatgtt 2300

 tagagtggat agaaaattat gcagcttgca cacccatcat ctttaacccc 2350

 aaatttcctt tggctattaa aaaagtggtg gcaaaaggca tcctcaaaag 2400

 aaagagaaat gaaatatttt tgaatggttg cacgttaaaa attaaaagaa 2450

 ggaatggggg cagaatgcca tatttttgag ggctgtacta ggtttatctc 2500

 atttaagccc cacaacaccc cacaggaggg taattttcta actctagttt 2550

 gcagaggagc aaattgaggt tcagcaaggt gagagaggta cccaaggtca 2600

 catagctagt tatgtgagaa agttagagta cagatcctct ggggtttcag 2650

 cttattgtag catattttct ccgaaaggca aaaatgtgcc cttttggccg 2700

 ggcatggtag ctcaagccta taatcccagc atgttgagag gctgaggtgg 2750

 gcagatcatt tgaggccagg agttcaagac cagtctggcc aatatggaga 2800

 aaccttgtct ctactaaaaa cacaaaaatt atctgggcat ggtggggcat 2850

 gcctgtagtc ccacttactt gggaggccga ggcacgagaa tcgcttgaac 2900

 ccgggaggtg gaggttgccg tgagccaaga tcacgccact gcactccagc 2950

 ctgggcaaca gagcaagact ctgtctcaaa aaaaaaaata caatatttta 3000

 acaatgtgcc ctcttaagtg tgcacagata cacatacacg gtattcccaa 3050

 gagtggtggc agctcaaaat gatatgtttg agtagacgaa cagctgacat 3100

 ggagttcccg tgcacctacg gaaggggacg ctttgaagga accaagtgca 3150

 tttttatctg tgagttctgt tgtgtttgtc aaaaagtcat tgtaatcttt 3200

 catagccata cctggtaagc aaaaactagt aaagacatag gaacatgtag 3250

 ttttacttgg tgtttatgtt gcaatctggt tgtgatttat attttaaagc 3300

 ttggtgctaa accacaatat gtatagcaca tggagtgcct gtacaagctg 3350

 atgttttgta ttttgtgttc ctctttgcat gatctgtcaa agtgagatat 3400

 ttttacctgc ctaaaatatg atgtttaaaa gcatactcta tgtgatttat 3450

 ttatttctac ctttctgagt ctcttggact aagaagatgt tttgaaatgt 3500

 accatcaaat gttaacagag tttgatatgg gctttctctt tggtttctca 3550

 tcacatttgt aaatgtcttt tcaaaaggat ttactttttg taaaaagctt 3600

 cattctcact ctgctttgca tcccccaaac ttcttgttca aaacgggggg 3650

 agtttaggag actttaatcc cggtttcaga agctgcagct ggtctgtttc 3700

 caggtcagaa accattgttc agaagacctc cctgtgagag agttgctcct 3750

 cagggtccct caggaccaaa gaacactcga aaagagcact tcacacagac 3800

 aagtggctaa gtgtccatta tttaccttga acaatcaagg caactagtgg 3850

 agagaactga ttgtgagctc 3870

<210> 1390
<211> 487
<212> PRT
<213> Homo sapien

<400> 1390
 Met Ser Leu Pro Asn Ser Ser Cys Leu Leu Glu Asp Lys Met Cys
   1               5                  10                  15

 Glu Gly Asn Lys Thr Thr Met Ala Ser Pro Gln Leu Met Pro Leu
                  20                  25                  30

 Val Val Val Leu Ser Thr Ile Cys Leu Val Thr Val Gly Leu Asn
                  35                  40                  45

 Leu Leu Val Leu Tyr Ala Val Arg Ser Glu Arg Lys Leu His Thr
                  50                  55                  60

 Val Gly Asn Leu Tyr Ile Val Ser Leu Ser Val Ala Asp Leu Ile
                  65                  70                  75

 Val Gly Ala Val Val Met Pro Met Asn Ile Leu Tyr Leu Leu Met
                  80                  85                  90

 Ser Lys Trp Ser Leu Gly Arg Pro Leu Cys Leu Phe Trp Leu Ser
                  95                 100                 105

 Met Asp Tyr Val Ala Ser Thr Ala Ser Ile Phe Ser Val Phe Ile
                 110                 115                 120

 Leu Cys Ile Asp Arg Tyr Arg Ser Val Gln Gln Pro Leu Arg Tyr
                 125                 130                 135

 Leu Lys Tyr Arg Thr Lys Thr Arg Ala Ser Ala Thr Ile Leu Gly
                 140                 145                 150

 Ala Trp Phe Leu Ser Phe Leu Trp Val Ile Pro Ile Leu Gly Trp
                 155                 160                 165

 Asn His Phe Met Gln Gln Thr Ser Val Arg Arg Glu Asp Lys Cys
                 170                 175                 180

 Glu Thr Asp Phe Tyr Asp Val Thr Trp Phe Lys Val Met Thr Ala
                 185                 190                 195

 Ile Ile Asn Phe Tyr Leu Pro Thr Leu Leu Met Leu Trp Phe Tyr
                 200                 205                 210

 Ala Lys Ile Tyr Lys Ala Val Arg Gln His Cys Gln His Arg Glu
                 215                 220                 225

 Leu Ile Asn Arg Ser Leu Pro Ser Phe Ser Glu Ile Lys Leu Arg
                 230                 235                 240

 Pro Glu Asn Pro Lys Gly Asp Ala Lys Lys Pro Gly Lys Glu Ser
                 245                 250                 255

 Pro Trp Glu Val Leu Lys Arg Lys Pro Lys Asp Ala Gly Gly Gly
                 260                 265                 270

 Ser Val Leu Lys Ser Pro Ser Gln Thr Pro Lys Glu Met Lys Ser
                 275                 280                 285

 Pro Val Val Phe Ser Gln Glu Asp Asp Arg Glu Val Asp Lys Leu
                 290                 295                 300

 Tyr Cys Phe Pro Leu Asp Ile Val His Met Gln Ala Ala Ala Glu
                 305                 310                 315

 Gly Ser Ser Arg Asp Tyr Val Ala Val Asn Arg Ser His Gly Gln
                 320                 325                 330

 Leu Lys Thr Asp Glu Gln Gly Leu Asn Thr His Gly Ala Ser Glu
                 335                 340                 345

 Ile Ser Glu Asp Gln Met Leu Gly Asp Ser Gln Ser Phe Ser Arg
                 350                 355                 360

 Thr Asp Ser Asp Thr Thr Thr Glu Thr Ala Pro Gly Lys Gly Lys
                 365                 370                 375

 Leu Arg Ser Gly Ser Asn Thr Gly Leu Asp Tyr Ile Lys Phe Thr
                 380                 385                 390

 Trp Lys Arg Leu Arg Ser His Ser Arg Gln Tyr Val Ser Gly Leu
                 395                 400                 405

 His Met Asn Arg Glu Arg Lys Ala Ala Lys Gln Leu Gly Phe Ile
                 410                 415                 420

 Met Ala Ala Phe Ile Leu Cys Trp Ile Pro Tyr Phe Ile Phe Phe
                 425                 430                 435

 Met Val Ile Ala Phe Cys Lys Asn Cys Cys Asn Glu His Leu His
                 440                 445                 450

 Met Phe Thr Ile Trp Leu Gly Tyr Ile Asn Ser Thr Leu Asn Pro
                 455                 460                 465

 Leu Ile Tyr Pro Leu Cys Asn Glu Asn Phe Lys Lys Thr Phe Lys
                 470                 475                 480

 Arg Ile Leu His Ile Arg Ser
                 485

<210> 1391
<211> 5428
<212> DNA
<213> Homo sapien

<400> 1391
 gcggggagcc ggcggttatc tgggcggcgg agcgctcaca atgtggcagg 50

 agacagaaaa gataagatgc tcccaagtcc cttgcagctc tcttcagaag 100

 aaaaatcact agtgctctgc tcttgccata ataccaaacc tttttgactc 150

 atgctttggt gctgcaacac tggaagaatt gcacacagtt tccaggaata 200

 tctttttttc atttgagtga ttctttgtgg atgagaaaag atttgagtct 250

 taataattac cttgttttaa agctatttct ttatagtctg aactgtttaa 300

 taaattgggc cacttaccaa tgagccacac agccagttct tgtcaggagc 350

 tggttgaaaa ctgtgctgtg catgtagcag gaatggcaca agaagatagc 400

 cgtcgtggtc aagtgccatc ttccttttat catggtgcca accaagaact 450

 tgacctgtcc accaaagtgt acaaaaggga atcaggaagt ccttattctg 500

 tgttagtgga caccaagatg agcaaaccgc atctccatga aacagaagaa 550

 cagccatatt tcagggagac aagagcagtg tctgacgtgc atgctgttaa 600

 ggaagaccgg gagaattctg atgacacaga ggaggaagag gaagaagtct 650

 cttacaaaag ggagcagatc atagtggagg taaaccttaa taatcaaaca 700

 ttaaatgtat ctaaagggga aaagggtgtc tcttctcagt ccaaagagac 750

 tcctgttctt aagacaagca gtgaggagga agaggaagag agtgaggaag 800

 aggccacaga tgacagcaat gactatggag agaatgaaaa gcagaagaaa 850

 aaggagaaga tagtagagaa agtcagcgtt acacaaagga gaaccaggag 900

 agctgcctct gttgccgcag ctaccacttc ccctactccc agaactacaa 950

 gaggtcgtag gaagagtgta gagccaccta agcgtaagaa gcgggccaca 1000

 aaggagccca aagcaccagt ccagaaagct aagtgtgaag agaaagagac 1050

 tctgacctgt gagaagtgcc ccagggtatt taacactcgc tggtacctgg 1100

 agaagcacat gaacgttact cataggcgca tgcagatttg tgataaatgt 1150

 ggcaagaagt ttgtcctgga aagtgagctg tcccttcacc agcaaacaga 1200

 ctgtgaaaaa aacattcagt gtgtttcctg taacaaatcg ttcaagaaac 1250

 tctggtccct tcatgaacat atcaagatcg tccatggata tgcagaaaag 1300

 aaattttcct gtgaaatttg tgagaagaaa ttctatacca tggctcatgt 1350

 gcggaaacac atggttgcac acacaaaaga catgccattt acatgcgaaa 1400

 cctgtggaaa atcattcaaa cgcagtatgt cactcaaggt gcactccttg 1450

 cagcattctg gagagaagcc ctttagatgc gagaactgtg acgaaaggtt 1500

 tcagtacaag taccagctac gctcccacat gagcattcat attgggcaca 1550

 aacagttcat gtgccagtgg tgtggcaagg atttcaacat gaagcagtac 1600

 ttcgacgaac acatgaaaac acacactgga gagaaaccct ttatctgtga 1650

 aatctgtggc aaaagcttca ccagccgccc caacatgaag agacaccgca 1700

 gaactcacac aggcgagaag ccctatccat gtgatgtgtg tggccagcgg 1750

 ttccgcttct cgaacatgct taaggcccac aaggagaagt gctttcgggt 1800

 gaccagcccc gtgaatgtgc cacctgctgt ccagatccca cttacaactt 1850

 ccccagccac cccagttcct tctgtggtga acacagccac aaccccaacc 1900

 cctccaatca atatgaatcc tgtaagcact cttccccctc ggcccatccc 1950

 ccaccccttc tcacacctgc acatccaccc acaccctcac cacccacacc 2000

 accttcccat ccctccagtc cctcacctcc cgccacctcc agctctcttt 2050

 aagagtgagc ctttaaatca tagaggccag agtgaggaca actttctgcg 2100

 gcacctggca gagaagaaca gttcagcaca gcatcattaa catccgtctc 2150

 cttagtgtgt tctccaggag acacgtcccc atgtgtgagc gtgcacagag 2200

 ggagtcggtg agcatttcct tagttctcag actctcctcc gcctctacca 2250

 agagcttcgc cagtgtcact gaatcaacag atccaaggga atgaacaaga 2300

 agactacctt gagctcacag agggactgtc atctaaacca ggggaaccac 2350

 tgaactaaag cccaatttgc ttgcattttc tgatgacttt tataagtttc 2400

 aaatactcag acttgtggaa ttttataatt tcatatcagc tgatgaggta 2450

 tgcttgcttt tatatcccag acttctcctc aaagagggga taggcctggt 2500

 ttcctttgta ctaatcggga aggctgtgag attaatccag agcattaatt 2550

 gtatcactgt gtatggtaag gaattctttt cagcttttgg tgccagctac 2600

 agagttgagc tggccatgtt tcacagtata tcaagcatta tagagaaaga 2650

 cagaaatttt cttctttgtg tagctctcct aacgcactct ttattttact 2700

 acagaaatta ttttagagtt tttgtataga cttctttggt agtctgtttc 2750

 taaaatgaaa tgtatttcaa taagcagtgt aattttttca gtgtagctga 2800

 acctatgttg taaaatagaa aaaaattttt ataatcatca aaatgtgatt 2850

 cttaaagatg catataactt ctataattca aagctattct tacatccgta 2900

 caactcaaaa ggtgcttcag agactagatg tatctgagag ggtctccaga 2950

 ccaggttact gcaaaaatga ggttttgctt tcaggatttg gcgtaaatac 3000

 ttggtagttt tgacatctct gcttaacact caagagaggc tccctaatgt 3050

 gctcctgtcc tccatgttct gcttggcttc gttagtgcat tacatgaaat 3100

 gatttgcagg ggatggggcc ttttccaggg aagtcaccta aagcttgcat 3150

 gttttgaaaa tttgaataag gctgtttgct gacaggagga ggaagtagtg 3200

 gagatcattt catctcagtc acgtctgttt ctcacttccc ttaggaattg 3250

 tgttgatgtt taacttttat gggatgacaa attgaaatcg ctcattttga 3300

 ggttgcttta tttttctaga attgttataa gaagctaaaa tagtaaactt 3350

 aaaatcacaa acatgacatt gctgatagtg gctgagaaat tcagatgaga 3400

 agacaaattg gttatgaatt ttgaaatatc tattatatgt aaaatgtgga 3450

 tatgttcaca accttgagct attttaacac agtttaaata tagtgaggga 3500

 aaactcctaa gttttactgc cctgtcctct gcaaattatg taataccagc 3550

 attcttaggc gataaagaga gcagcacctc tagtaccttt aggcagatta 3600

 ctttttcaag tttggggaac ttcaaaagac cataatcaac caggagctta 3650

 ttataggaaa ggctgaacag aagggctagt gtattgatta cacttaacag 3700

 atcatattta tccagactca gtatagctta aaattttgta tttctttatc 3750

 tgagagaact gagttcccag gctaaatcac ttacctccca ccccctctcc 3800

 aatttttttt ttaagagaca aggtcttgct atgttgccca ggctagagtg 3850

 cagtggctat tcacaggtgc agttatagca cactacagcc tccaactctt 3900

 gggttcaagc aaccctgcct cagctaacca agtagctggg actacaggtg 3950

 catgctacca tgcccagtcc attttttaat cttgaaattt cttcattttt 4000

 ctttcttcgg tttcttaaaa tctttgcctg aatcagaacg ctggctttta 4050

 tttatttttt tatttttaat attaaatgtg cagatatgct tcgagcactt 4100

 ttctaactaa tgagctctgt ggtaagaaaa aatgaactct ttcaattgag 4150

 attaagtcca tatttttcaa acatcacgtt ctctattggc tttttggttt 4200

 agtgtttcta aattttctcc ttctgatttt gcctgtctta tataatgagc 4250

 ataggaaaat tttggaatga ggcagaaaag tatatcaaga catacttcct 4300

 ggttttggat gtaagtttta aagaatggta tttttaatat ttgtacacat 4350

 tctttgagca cccaggtacc caagccaata aggaaagtta attccttgca 4400

 tatgactgtt atatctttag tggttgtctc cctctccctc cacagtctcc 4450

 ttggcattcc atgacaagtt tgtcaaccta cacttttata tagacatgtc 4500

 attatttcat ggtcaagcct gtagtattaa aatgattttt ttaaaagatg 4550

 taaactgtgc ttagttaatt ggttatattt tgttctgttt tttttttttt 4600

 tttttttttt ttttgaggca gagtcttgtt ctgttgcctg ggctggagtg 4650

 cagtggcgtg atcttggctc actgcaaccc ccgccccccg ggttcaagtg 4700

 attctcctgc ctcagcctcc cgagtagctg gaattacagg catgcgccag 4750

 cacgcccggc taagttttgt atttttggca gagatggggt ttcaccatat 4800

 tggccaggct ggtctcaaac tcctgacctt gtgatccgcc cacctcagcc 4850

 tccgaaagtg ctgggattac aggcgtgagc caccacgtcc aactgcctta 4900

 ttttgttctg aataaattta cagtattggg cagcaattct ggattctaga 4950

 cttgagacca cagaatcaac catttcatga ggttgtactg taattataca 5000

 ctggaatatt caggtagtca tctttgattt ttcattcaag taaatatagc 5050

 cataagaaaa tatctgctat acaggaaaac cagtattaag caaataccac 5100

 catccttaac agaaacaaaa atatatatat atattatttt taaaaattag 5150

 cattgtcata cagtacaatt cttagtgaag tgtattgtgg aacaatttag 5200

 aaacttcctt tttttcccct agattaagga tactttcctt gacttgagac 5250

 ttgtggtctt caggaaaact actcagaata taatgactcc tcatcagtat 5300

 catattgtat ataaataatg aaatgcatta agaatattca caacattgaa 5350

 cccaggaggc ggagcttgca gtgagccgag attgcgccac tgcgctccag 5400

 cctgggcaac agagcgagac tccatctc 5428

<210> 1392
<211> 606
<212> PRT
<213> Homo sapien

<400> 1392
 Met Ser His Thr Ala Ser Ser Cys Gln Glu Leu Val Glu Asn Cys
   1               5                  10                  15

 Ala Val His Val Ala Gly Met Ala Gln Glu Asp Ser Arg Arg Gly
                  20                  25                  30

 Gln Val Pro Ser Ser Phe Tyr His Gly Ala Asn Gln Glu Leu Asp
                  35                  40                  45

 Leu Ser Thr Lys Val Tyr Lys Arg Glu Ser Gly Ser Pro Tyr Ser
                  50                  55                  60

 Val Leu Val Asp Thr Lys Met Ser Lys Pro His Leu His Glu Thr
                  65                  70                  75

 Glu Glu Gln Pro Tyr Phe Arg Glu Thr Arg Ala Val Ser Asp Val
                  80                  85                  90

 His Ala Val Lys Glu Asp Arg Glu Asn Ser Asp Asp Thr Glu Glu
                  95                 100                 105

 Glu Glu Glu Glu Val Ser Tyr Lys Arg Glu Gln Ile Ile Val Glu
                 110                 115                 120

 Val Asn Leu Asn Asn Gln Thr Leu Asn Val Ser Lys Gly Glu Lys
                 125                 130                 135

 Gly Val Ser Ser Gln Ser Lys Glu Thr Pro Val Leu Lys Thr Ser
                 140                 145                 150

 Ser Glu Glu Glu Glu Glu Glu Ser Glu Glu Glu Ala Thr Asp Asp
                 155                 160                 165

 Ser Asn Asp Tyr Gly Glu Asn Glu Lys Gln Lys Lys Lys Glu Lys
                 170                 175                 180

 Ile Val Glu Lys Val Ser Val Thr Gln Arg Arg Thr Arg Arg Ala
                 185                 190                 195

 Ala Ser Val Ala Ala Ala Thr Thr Ser Pro Thr Pro Arg Thr Thr
                 200                 205                 210

 Arg Gly Arg Arg Lys Ser Val Glu Pro Pro Lys Arg Lys Lys Arg
                 215                 220                 225

 Ala Thr Lys Glu Pro Lys Ala Pro Val Gln Lys Ala Lys Cys Glu
                 230                 235                 240

 Glu Lys Glu Thr Leu Thr Cys Glu Lys Cys Pro Arg Val Phe Asn
                 245                 250                 255

 Thr Arg Trp Tyr Leu Glu Lys His Met Asn Val Thr His Arg Arg
                 260                 265                 270

 Met Gln Ile Cys Asp Lys Cys Gly Lys Lys Phe Val Leu Glu Ser
                 275                 280                 285

 Glu Leu Ser Leu His Gln Gln Thr Asp Cys Glu Lys Asn Ile Gln
                 290                 295                 300

 Cys Val Ser Cys Asn Lys Ser Phe Lys Lys Leu Trp Ser Leu His
                 305                 310                 315

 Glu His Ile Lys Ile Val His Gly Tyr Ala Glu Lys Lys Phe Ser
                 320                 325                 330

 Cys Glu Ile Cys Glu Lys Lys Phe Tyr Thr Met Ala His Val Arg
                 335                 340                 345

 Lys His Met Val Ala His Thr Lys Asp Met Pro Phe Thr Cys Glu
                 350                 355                 360

 Thr Cys Gly Lys Ser Phe Lys Arg Ser Met Ser Leu Lys Val His
                 365                 370                 375

 Ser Leu Gln His Ser Gly Glu Lys Pro Phe Arg Cys Glu Asn Cys
                 380                 385                 390

 Asp Glu Arg Phe Gln Tyr Lys Tyr Gln Leu Arg Ser His Met Ser
                 395                 400                 405

 Ile His Ile Gly His Lys Gln Phe Met Cys Gln Trp Cys Gly Lys
                 410                 415                 420

 Asp Phe Asn Met Lys Gln Tyr Phe Asp Glu His Met Lys Thr His
                 425                 430                 435

 Thr Gly Glu Lys Pro Phe Ile Cys Glu Ile Cys Gly Lys Ser Phe
                 440                 445                 450

 Thr Ser Arg Pro Asn Met Lys Arg His Arg Arg Thr His Thr Gly
                 455                 460                 465

 Glu Lys Pro Tyr Pro Cys Asp Val Cys Gly Gln Arg Phe Arg Phe
                 470                 475                 480

 Ser Asn Met Leu Lys Ala His Lys Glu Lys Cys Phe Arg Val Thr
                 485                 490                 495

 Ser Pro Val Asn Val Pro Pro Ala Val Gln Ile Pro Leu Thr Thr
                 500                 505                 510

 Ser Pro Ala Thr Pro Val Pro Ser Val Val Asn Thr Ala Thr Thr
                 515                 520                 525

 Pro Thr Pro Pro Ile Asn Met Asn Pro Val Ser Thr Leu Pro Pro
                 530                 535                 540

 Arg Pro Ile Pro His Pro Phe Ser His Leu His Ile His Pro His
                 545                 550                 555

 Pro His His Pro His His Leu Pro Ile Pro Pro Val Pro His Leu
                 560                 565                 570

 Pro Pro Pro Pro Ala Leu Phe Lys Ser Glu Pro Leu Asn His Arg
                 575                 580                 585

 Gly Gln Ser Glu Asp Asn Phe Leu Arg His Leu Ala Glu Lys Asn
                 590                 595                 600

 Ser Ser Ala Gln His His
                 605

<210> 1393
<211> 2916
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2534, 2536
<223> Unknown base

<400> 1393
 ggggagctcg gcgtcccgct ccctccgcgg ctcatggcga cgactctcgg 50

 cacatccggg accctccggc cgtggcggcc gaggcgccgg ctgctcgggc 100

 cccagccccg gccgctgtgg tgactccgcc gcgcctcgcc gtcgcccccg 150

 tgccgcccgc cgcccccgcc gcccccgccg ccggggacat gtctaacccc 200

 ggaggccgga ggaacgggcc cgtcaagctg cgcctgacag tactctgtgc 250

 aaaaaacctg gtgaaaaagg attttttccg acttcctgat ccatttgcta 300

 aggtggtggt tgatggatct gggcaatgcc attctacaga tactgtgaag 350

 aatacgcttg atccaaagtg gaatcagcat tatgacctgt atattggaaa 400

 gtctgattca gttacgatca gtgtatggaa tcacaagaag atccataaga 450

 aacaaggtgc tggatttctc ggttgtgttc gtcttctttc caatgccatc 500

 aaccgcctca aagacactgg ttatcagagg ttggatttat gcaaactcgg 550

 gccaaatgac aatgatacag ttagaggaca gatagtagta agtcttcagt 600

 ccagagaccg aataggcaca ggaggacaag ttgtggactg cagtcgttta 650

 tttgataacg atttaccaga cggctgggaa gaaaggagaa ccgcctctgg 700

 aagaatccag tatctaaacc atataacaag aactacgcaa tgggagcgcc 750

 caacacgacc ggcatccgaa tattctagcc ctggcagacc tcttagctgc 800

 tttgttgatg agaacactcc aattagtgga acaaatggtg caacatgtgg 850

 acagtcttca gatcccaggc tggcagagag gagagtcagg tcacaacgac 900

 atagaaatta catgagcaga acacatttac atactcctcc agacctacca 950

 gaaggctatg aacagaggac aacgcaacaa ggccaggtgt atttcttaca 1000

 tacacagact ggtgtgagca catggcatga tccaagagtg cccagggatc 1050

 ttagcaacat caattgtgaa gagcttggtc cattgcctcc tggatgggag 1100

 atccgtaata cggcaacagg cagagtttat ttcgttgacc ataacaacag 1150

 aacaacacaa tttacagatc ctcggctgtc tgctaacttg catttagttt 1200

 taaatcggca gaaccaattg aaagaccaac agcaacagca agtggtatcg 1250

 ttatgtcctg atgacacaga atgcctgaca gtcccaaggt acaagcgaga 1300

 cctggttcag aaactaaaaa ttttgcggca agaactttcc caacaacagc 1350

 ctcaggcagg tcattgccgc attgaggttt ccagggaaga gatttttgag 1400

 gaatcatatc gacaggtcat gaaaatgaga ccaaaagatc tctggaagcg 1450

 attaatgata aaatttcgtg gagaagaagg ccttgactat ggaggcgttg 1500

 ccagggaatg gttgtatctc ttgtcacatg aaatgttgaa tccatactat 1550

 ggcctcttcc agtattcaag agatgatatt tatacattgc agatcaatcc 1600

 tgattctgca gttaatccgg aacatttatc ctatttccac tttgttggac 1650

 gaataatggg aatggctgtg tttcatggac attatattga tggtggtttc 1700

 acattgcctt tttataagca attgcttggg aagtcaatta ccttggatga 1750

 catggagtta gtagatccgg atcttcacaa cagtttagtg tggatacttg 1800

 agaatgatat tacaggtgtt ttggaccata ccttctgtgt tgaacataat 1850

 gcatatggtg aaattattca gcatgaactt aaaccaaatg gcaaaagtat 1900

 ccctgttaat gaagaaaata aaaaagaata tgtcaggctc tatgtgaact 1950

 ggagattttt acgaggcatt gaggctcaat tcttggctct gcagaaagga 2000

 tttaatgaag taattccaca acatctgctg aagacatttg atgagaagga 2050

 gttagagctc attatttgtg gacttggaaa gatagatgtt aatgactgga 2100

 aggtaaacac ccggttaaaa cactgtacac cagacagcaa cattgtcaaa 2150

 tggttctgga aagctgtgga gttttttgat gaagagcgac gagcaagatt 2200

 gcttcagttt gtgacaggat cctctcgagt gcctctgcag ggcttcaaag 2250

 cattgcaagg tgctgcaggc ccgagactct ttaccataca ccagattgat 2300

 gcctgcacta acaacctgcc gaaagcccac acttgcttca atcgaataga 2350

 cattccaccc tatgaaagct atgaaaagct atatgaaaag ctgctaacag 2400

 ccattgaaga aacatgtgga tttgctgtgg aatgacaagc ttcaaggatt 2450

 tacccaggac tctatttata caaccctgac tgacagcctc ctttcagcag 2500

 agtttcaaag aatatgctga aatacaggaa aacncncccc ccccccccct 2550

 tttttttttt tttttacatt ttaggacact gtgaggggaa aggacaattt 2600

 tgaaattcct tttcaaggaa aaaaaggtct ttatgctttg ccatgaggcc 2650

 acattcagct gctatttaaa cttaatatct tgaacctaaa gaatgctgac 2700

 ttttcctaca tttccagagt taggcagtat tctacactta aagactacta 2750

 ctatttttat aaaaggtaat ctattcaaat ttcttcacag atttcaagtc 2800

 tctcaaacat caagacaact tcagcagtcg gtacaagtca catttcattt 2850

 tgattgaata catgatcttg aacagctcct gtacttgctc tttgtaaaaa 2900

 aaaataaaat tatttt 2916

<210> 1394
<211> 748
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2534, 2536
<223> Unknown amino acid

<400> 1394
 Met Ser Asn Pro Gly Gly Arg Arg Asn Gly Pro Val Lys Leu Arg
   1               5                  10                  15

 Leu Thr Val Leu Cys Ala Lys Asn Leu Val Lys Lys Asp Phe Phe
                  20                  25                  30

 Arg Leu Pro Asp Pro Phe Ala Lys Val Val Val Asp Gly Ser Gly
                  35                  40                  45

 Gln Cys His Ser Thr Asp Thr Val Lys Asn Thr Leu Asp Pro Lys
                  50                  55                  60

 Trp Asn Gln His Tyr Asp Leu Tyr Ile Gly Lys Ser Asp Ser Val
                  65                  70                  75

 Thr Ile Ser Val Trp Asn His Lys Lys Ile His Lys Lys Gln Gly
                  80                  85                  90

 Ala Gly Phe Leu Gly Cys Val Arg Leu Leu Ser Asn Ala Ile Asn
                  95                 100                 105

 Arg Leu Lys Asp Thr Gly Tyr Gln Arg Leu Asp Leu Cys Lys Leu
                 110                 115                 120

 Gly Pro Asn Asp Asn Asp Thr Val Arg Gly Gln Ile Val Val Ser
                 125                 130                 135

 Leu Gln Ser Arg Asp Arg Ile Gly Thr Gly Gly Gln Val Val Asp
                 140                 145                 150

 Cys Ser Arg Leu Phe Asp Asn Asp Leu Pro Asp Gly Trp Glu Glu
                 155                 160                 165

 Arg Arg Thr Ala Ser Gly Arg Ile Gln Tyr Leu Asn His Ile Thr
                 170                 175                 180

 Arg Thr Thr Gln Trp Glu Arg Pro Thr Arg Pro Ala Ser Glu Tyr
                 185                 190                 195

 Ser Ser Pro Gly Arg Pro Leu Ser Cys Phe Val Asp Glu Asn Thr
                 200                 205                 210

 Pro Ile Ser Gly Thr Asn Gly Ala Thr Cys Gly Gln Ser Ser Asp
                 215                 220                 225

 Pro Arg Leu Ala Glu Arg Arg Val Arg Ser Gln Arg His Arg Asn
                 230                 235                 240

 Tyr Met Ser Arg Thr His Leu His Thr Pro Pro Asp Leu Pro Glu
                 245                 250                 255

 Gly Tyr Glu Gln Arg Thr Thr Gln Gln Gly Gln Val Tyr Phe Leu
                 260                 265                 270

 His Thr Gln Thr Gly Val Ser Thr Trp His Asp Pro Arg Val Pro
                 275                 280                 285

 Arg Asp Leu Ser Asn Ile Asn Cys Glu Glu Leu Gly Pro Leu Pro
                 290                 295                 300

 Pro Gly Trp Glu Ile Arg Asn Thr Ala Thr Gly Arg Val Tyr Phe
                 305                 310                 315

 Val Asp His Asn Asn Arg Thr Thr Gln Phe Thr Asp Pro Arg Leu
                 320                 325                 330

 Ser Ala Asn Leu His Leu Val Leu Asn Arg Gln Asn Gln Leu Lys
                 335                 340                 345

 Asp Gln Gln Gln Gln Gln Val Val Ser Leu Cys Pro Asp Asp Thr
                 350                 355                 360

 Glu Cys Leu Thr Val Pro Arg Tyr Lys Arg Asp Leu Val Gln Lys
                 365                 370                 375

 Leu Lys Ile Leu Arg Gln Glu Leu Ser Gln Gln Gln Pro Gln Ala
                 380                 385                 390

 Gly His Cys Arg Ile Glu Val Ser Arg Glu Glu Ile Phe Glu Glu
                 395                 400                 405

 Ser Tyr Arg Gln Val Met Lys Met Arg Pro Lys Asp Leu Trp Lys
                 410                 415                 420

 Arg Leu Met Ile Lys Phe Arg Gly Glu Glu Gly Leu Asp Tyr Gly
                 425                 430                 435

 Gly Val Ala Arg Glu Trp Leu Tyr Leu Leu Ser His Glu Met Leu
                 440                 445                 450

 Asn Pro Tyr Tyr Gly Leu Phe Gln Tyr Ser Arg Asp Asp Ile Tyr
                 455                 460                 465

 Thr Leu Gln Ile Asn Pro Asp Ser Ala Val Asn Pro Glu His Leu
                 470                 475                 480

 Ser Tyr Phe His Phe Val Gly Arg Ile Met Gly Met Ala Val Phe
                 485                 490                 495

 His Gly His Tyr Ile Asp Gly Gly Phe Thr Leu Pro Phe Tyr Lys
                 500                 505                 510

 Gln Leu Leu Gly Lys Ser Ile Thr Leu Asp Asp Met Glu Leu Val
                 515                 520                 525

 Asp Pro Asp Leu His Asn Ser Leu Val Trp Ile Leu Glu Asn Asp
                 530                 535                 540

 Ile Thr Gly Val Leu Asp His Thr Phe Cys Val Glu His Asn Ala
                 545                 550                 555

 Tyr Gly Glu Ile Ile Gln His Glu Leu Lys Pro Asn Gly Lys Ser
                 560                 565                 570

 Ile Pro Val Asn Glu Glu Asn Lys Lys Glu Tyr Val Arg Leu Tyr
                 575                 580                 585

 Val Asn Trp Arg Phe Leu Arg Gly Ile Glu Ala Gln Phe Leu Ala
                 590                 595                 600

 Leu Gln Lys Gly Phe Asn Glu Val Ile Pro Gln His Leu Leu Lys
                 605                 610                 615

 Thr Phe Asp Glu Lys Glu Leu Glu Leu Ile Ile Cys Gly Leu Gly
                 620                 625                 630

 Lys Ile Asp Val Asn Asp Trp Lys Val Asn Thr Arg Leu Lys His
                 635                 640                 645

 Cys Thr Pro Asp Ser Asn Ile Val Lys Trp Phe Trp Lys Ala Val
                 650                 655                 660

 Glu Phe Phe Asp Glu Glu Arg Arg Ala Arg Leu Leu Gln Phe Val
                 665                 670                 675

 Thr Gly Ser Ser Arg Val Pro Leu Gln Gly Phe Lys Ala Leu Gln
                 680                 685                 690

 Gly Ala Ala Gly Pro Arg Leu Phe Thr Ile His Gln Ile Asp Ala
                 695                 700                 705

 Cys Thr Asn Asn Leu Pro Lys Ala His Thr Cys Phe Asn Arg Ile
                 710                 715                 720

 Asp Ile Pro Pro Tyr Glu Ser Tyr Glu Lys Leu Tyr Glu Lys Leu
                 725                 730                 735

 Leu Thr Ala Ile Glu Glu Thr Cys Gly Phe Ala Val Glu
                 740                 745

<210> 1395
<211> 2412
<212> DNA
<213> Homo sapien

<400> 1395
 caggccagga ctccacaagg ctggtcccct gccctggagc aacttaaaca 50

 ggccctctgg ccagcctgga accctgagat ggcctccagc tcaggcagca 100

 gtcctcgccc ggcccctgat gagaatgagt ttccctttgg gtgccctccc 150

 accgtctgcc aggacccaaa ggagcccagg gctctctgct gtgcaggctg 200

 tctctctgag aacccgagga atggcgagga tcagatctgc cccaaatgca 250

 gaggggaaga cctccagtct ataagcccag gaagccgtct tcgaactcag 300

 gagaaggctc accccgaggt ggctgaggct ggaattgggt gcccctttgc 350

 aggtgtcggc tgctccttca agggaagccc acagtctgtg caagagcatg 400

 aggtcacctc ccagacctcc cacctaaacc tgctgttggg gttcatgaaa 450

 cagtggaagg cccggctggg ctgtggcctg gagtctgggc ccatggccct 500

 ggagcagaac ctgtcagacc tgcagctgca ggcagccgtg gaagtggcgg 550

 gggacctgga ggtcgattgc taccgggcac cctgctccga gagccaggag 600

 gagctggccc tgcagcactt catgaaggag aagcttctgg ctgagctgga 650

 ggggaagctg cgtgtgtttg agaacattgt tgctgtcctc aacaaggagg 700

 tggaggcctc ccacctggcc ctggccacct ctatccacca gagccagctg 750

 gaccgtgagc gcatcctgag cttggagcag agggtggtgg agcttcagca 800

 gaccctggcc cagaaagacc aggccctggg caagctggag cagagcttgc 850

 gcctcatgga ggaggcctcc ttcgatggca ctttcctgtg gaagatcacc 900

 aatgtcacca ggcggtgcca tgagtcggcc tgtggcagga ccgtcagcct 950

 cttctcccca gccttctaca ctgccaagta tggctacaag ttgtgcctgc 1000

 ggctgtacct gaatggagat ggcactggaa agagaaccca tctgtcgctc 1050

 ttcatcgtga tcatgagagg ggagtatgat gcgctgctgc cgtggccttt 1100

 ccggaacaag gtcaccttca tgctgctgga ccagaacaac cgtgagcacg 1150

 ccattgacgc cttccggcct gacctaagct cagcgtcctt ccagaggccc 1200

 cagagtgaaa ccaacgtggc cagtggatgc ccactcttct tccccctcag 1250

 caaactgcag tcacccaagc acgcctacgt gaaggacgac acaatgttcc 1300

 tcaagtgcat tgtggagacc agcacttagg gtgggcgggg ctcctgaggg 1350

 agctccaact cagaagggag ctagccagag gactgtgatg ccctgccctt 1400

 ggcacccaag acctcagggc acaaagatgg gtgaaggctg gcatgatcca 1450

 agcaagactg aggggtcgac ttcgggctgg ccatctggtt aggatggcag 1500

 gacgtgggct gggcccacaa aggcaaaggg tccagaagga gacaggcaga 1550

 gctgctcccc tctgcacgga ccatgcgaca ctgggaggcc agtgagccac 1600

 tccggccccg aatgttgagg tggactctca ccaaatgaga agaaaatgga 1650

 accaggcttg gaaccgtagg acccaagcag agaagctctc gggctaggaa 1700

 gatctctgca gggccgccag ggagacctgg acacaggcct gctctctttt 1750

 tctccagggt cagaaacagg accgggtgga agggatgggg tgccagtttg 1800

 aatgcagtct gtccaggctc gtcattggag gtgaacaagc aaacccagag 1850

 ggctccacta ggacttcaaa ttgggggttg gatttgaaga cttttaagtt 1900

 tccttccagc ccagaaagtc tctcattcta ggcctcctgg cccaggtgag 1950

 tcctagagct acaggggttc tggaaacatt caggagcttc ctgtcctccc 2000

 agctcctcac tcaccttcag taacccccac tggactgacc tggtccacag 2050

 ggcacctgcc accctgggcc tggcagctca gcttccccaa cacgcaggag 2100

 cacacccagc ccccacatcc tgtgcctcca tcagctaaac accacgtcac 2150

 ttcatgcagg tgaaacccag tcactgtgag ctcccaggtg cagccagagg 2200

 cacctcaaga agaagagggg cataaacttt cctcttcctg cctagaggcc 2250

 ccacctttgg tgctttccag aatcccgtaa cacctgatta actgaggcat 2300

 ccacttcttt cagcagactg atcaggacct ccaagccact gagcaatgta 2350

 taaccccaaa gaaataattt ttagaatctc tttcgaagtt ttcctaaaaa 2400

 aaaaaaaaaa aa 2412

<210> 1396
<211> 416
<212> PRT
<213> Homo sapien

<400> 1396
 Met Ala Ser Ser Ser Gly Ser Ser Pro Arg Pro Ala Pro Asp Glu
   1               5                  10                  15

 Asn Glu Phe Pro Phe Gly Cys Pro Pro Thr Val Cys Gln Asp Pro
                  20                  25                  30

 Lys Glu Pro Arg Ala Leu Cys Cys Ala Gly Cys Leu Ser Glu Asn
                  35                  40                  45

 Pro Arg Asn Gly Glu Asp Gln Ile Cys Pro Lys Cys Arg Gly Glu
                  50                  55                  60

 Asp Leu Gln Ser Ile Ser Pro Gly Ser Arg Leu Arg Thr Gln Glu
                  65                  70                  75

 Lys Ala His Pro Glu Val Ala Glu Ala Gly Ile Gly Cys Pro Phe
                  80                  85                  90

 Ala Gly Val Gly Cys Ser Phe Lys Gly Ser Pro Gln Ser Val Gln
                  95                 100                 105

 Glu His Glu Val Thr Ser Gln Thr Ser His Leu Asn Leu Leu Leu
                 110                 115                 120

 Gly Phe Met Lys Gln Trp Lys Ala Arg Leu Gly Cys Gly Leu Glu
                 125                 130                 135

 Ser Gly Pro Met Ala Leu Glu Gln Asn Leu Ser Asp Leu Gln Leu
                 140                 145                 150

 Gln Ala Ala Val Glu Val Ala Gly Asp Leu Glu Val Asp Cys Tyr
                 155                 160                 165

 Arg Ala Pro Cys Ser Glu Ser Gln Glu Glu Leu Ala Leu Gln His
                 170                 175                 180

 Phe Met Lys Glu Lys Leu Leu Ala Glu Leu Glu Gly Lys Leu Arg
                 185                 190                 195

 Val Phe Glu Asn Ile Val Ala Val Leu Asn Lys Glu Val Glu Ala
                 200                 205                 210

 Ser His Leu Ala Leu Ala Thr Ser Ile His Gln Ser Gln Leu Asp
                 215                 220                 225

 Arg Glu Arg Ile Leu Ser Leu Glu Gln Arg Val Val Glu Leu Gln
                 230                 235                 240

 Gln Thr Leu Ala Gln Lys Asp Gln Ala Leu Gly Lys Leu Glu Gln
                 245                 250                 255

 Ser Leu Arg Leu Met Glu Glu Ala Ser Phe Asp Gly Thr Phe Leu
                 260                 265                 270

 Trp Lys Ile Thr Asn Val Thr Arg Arg Cys His Glu Ser Ala Cys
                 275                 280                 285

 Gly Arg Thr Val Ser Leu Phe Ser Pro Ala Phe Tyr Thr Ala Lys
                 290                 295                 300

 Tyr Gly Tyr Lys Leu Cys Leu Arg Leu Tyr Leu Asn Gly Asp Gly
                 305                 310                 315

 Thr Gly Lys Arg Thr His Leu Ser Leu Phe Ile Val Ile Met Arg
                 320                 325                 330

 Gly Glu Tyr Asp Ala Leu Leu Pro Trp Pro Phe Arg Asn Lys Val
                 335                 340                 345

 Thr Phe Met Leu Leu Asp Gln Asn Asn Arg Glu His Ala Ile Asp
                 350                 355                 360

 Ala Phe Arg Pro Asp Leu Ser Ser Ala Ser Phe Gln Arg Pro Gln
                 365                 370                 375

 Ser Glu Thr Asn Val Ala Ser Gly Cys Pro Leu Phe Phe Pro Leu
                 380                 385                 390

 Ser Lys Leu Gln Ser Pro Lys His Ala Tyr Val Lys Asp Asp Thr
                 395                 400                 405

 Met Phe Leu Lys Cys Ile Val Glu Thr Ser Thr
                 410                 415

<210> 1397
<211> 1279
<212> DNA
<213> Homo sapien

<400> 1397
 agaaactcag agaccaagtc cattgagaga ctgaggggaa agagaggaga 50

 gaaagaaaaa gagagtggga acagtaaaga gaaaggaaga caacctccag 100

 agaaagcccc cggagacgtc tctctgcaga gaggcggcag cacccggctc 150

 acctgcgaag cgcctgggaa gcgagtgccc ctaacatgcg gctgccgctg 200

 cttgtgtccg cgggagtcct gctggtggct ctcctgccct gcccgccatg 250

 cagggcgctc ctgagccgcg ggccggtccc gggagctcgg caggcgccgc 300

 agcaccctca gcccttggat ttcttccagc cgccgccgca gtccgagcag 350

 ccccagcagc cgcaggctcg gccggtcctg ctccgcatgg gagaggagta 400

 cttcctccgc ctggggaacc tcaacaagag cccggccgct cccctttcgc 450

 ccgcctcctc gctcctcgcc ggaggcagcg gcagccgccc ttcgccggaa 500

 caggcgaccg ccaacttttt ccgcgtgttg ctgcagcagc tgctgctgcc 550

 tcggcgctcg ctcgacagcc ccgcggctct cgcggagcgc ggcgctagga 600

 atgccctcgg cggccaccag gaggcaccgg agagagaaag gcggtccgag 650

 gagcctccca tctccctgga tctcaccttc cacctcctcc gggaagtctt 700

 ggaaatggcc agggccgagc agttagcaca gcaagctcac agcaacagga 750

 aactcatgga gattattggg aaataaaacg gtgcgtttgg ccaaaaagaa 800

 tctgcattta gcacaaaaaa aatttaaaaa aatacagtat tctgtaccat 850

 agcgctgctc ttatgccatt tgtttatttt tatatagctt gaaacataga 900

 gggagagagg gagagagcct atacccctta cttagcatgc acaaagtgta 950

 ttcacgtgca gcagcaacac aatgttattc gttttgtcta cgtttagttt 1000

 ccgtttccag gtgtttatag tggtgtttta aagagaatgt agacctgtga 1050

 gaaaacgttt tgtttgaaaa agcagacaga agtcactcaa ttgtttttgt 1100

 tgtggtctga gccaaagaga atgccattct cttgggtggg taagactaaa 1150

 tctgtaagct ctttgaaaca actttctctt gtaaacgttt cagtaataaa 1200

 acatctttcc agtccttggt cagtttggtt gtgtaagaga atgttgaata 1250

 cttatatttt taataaaagt tgcaaaggt 1279

<210> 1398
<211> 196
<212> PRT
<213> Homo sapien

<400> 1398
 Met Arg Leu Pro Leu Leu Val Ser Ala Gly Val Leu Leu Val Ala
   1               5                  10                  15

 Leu Leu Pro Cys Pro Pro Cys Arg Ala Leu Leu Ser Arg Gly Pro
                  20                  25                  30

 Val Pro Gly Ala Arg Gln Ala Pro Gln His Pro Gln Pro Leu Asp
                  35                  40                  45

 Phe Phe Gln Pro Pro Pro Gln Ser Glu Gln Pro Gln Gln Pro Gln
                  50                  55                  60

 Ala Arg Pro Val Leu Leu Arg Met Gly Glu Glu Tyr Phe Leu Arg
                  65                  70                  75

 Leu Gly Asn Leu Asn Lys Ser Pro Ala Ala Pro Leu Ser Pro Ala
                  80                  85                  90

 Ser Ser Leu Leu Ala Gly Gly Ser Gly Ser Arg Pro Ser Pro Glu
                  95                 100                 105

 Gln Ala Thr Ala Asn Phe Phe Arg Val Leu Leu Gln Gln Leu Leu
                 110                 115                 120

 Leu Pro Arg Arg Ser Leu Asp Ser Pro Ala Ala Leu Ala Glu Arg
                 125                 130                 135

 Gly Ala Arg Asn Ala Leu Gly Gly His Gln Glu Ala Pro Glu Arg
                 140                 145                 150

 Glu Arg Arg Ser Glu Glu Pro Pro Ile Ser Leu Asp Leu Thr Phe
                 155                 160                 165

 His Leu Leu Arg Glu Val Leu Glu Met Ala Arg Ala Glu Gln Leu
                 170                 175                 180

 Ala Gln Gln Ala His Ser Asn Arg Lys Leu Met Glu Ile Ile Gly
                 185                 190                 195

 Lys


<210> 1399
<211> 2254
<212> DNA
<213> Homo sapien

<400> 1399
 aaagaaccgc acaccacaga ctccctccag ctctttgtgt gtggctctct 50

 cagggtccaa caagagcaag ctgtgggtct gtgagtgttt atgtgtgctt 100

 ttattcactt cacacttatt gaaaagtgtg tatgtgagag ggtggggtgt 150

 gtgtgtcaaa gagagtgagg aagagaagga gagagagatc aattgattct 200

 gcagcctcag ctccagcatc cctcagttgg gagcttccaa agccgggtga 250

 tcacttgggg tgcatagctc ggagatgcag tccccctgga aaatccttac 300

 ggtggcgcct ctattcttgc tcctgtctct tcagtcctcg gcctctccag 350

 ccaacgatga ccagtccagg cccagcctct cgaatgggca cacctgtgta 400

 gggtgtgtgc tggtggtgtc tgtaatagaa cagcttgctc aagttcacaa 450

 ctcgacggtc caggcctcga tggagagact gtgcagctac ctgcctgaaa 500

 aactgttctt gaaaaccacc tgctatttag tcattgacaa gtttggatca 550

 gacatcataa aactgcttag cgcagatatg aatgctgatg tggtatgtca 600

 cactctggag ttttgtaaac agaacactgg ccaaccattg tgtcatctct 650

 accctcttcc caaggagaca tggaaattta cactacagaa ggcaagacaa 700

 attgtcaaga agtccccgat tctgaaatat tctagaagtg gttctgacat 750

 ttgttcactc ccggttttgg ccaagatctg ccagaaaatt aaattagcta 800

 tggaacagtc tgtgccattc aaagatgtgg attcagacaa atacagcgtt 850

 ttcccaacac tgcggggcta tcactggcgg gggagagact gtaatgacag 900

 cgacgagtca gtgtacccag gtagaaggcc gaacaactgg gatgtccatc 950

 aggattcaaa ctgtaatggc atttggggtg tcgatccaaa agatggagtt 1000

 ccatatgaga agaaattctg tgaaggttca cagcccaggg gaatcatttt 1050

 gctgggagac tcagctgggg ctcattttca catctctcct gaatggatca 1100

 cagcgtcgca gatgtctttg aactctttca tcaatctacc aacagccctt 1150

 accaacgagc ttgactggcc ccaactctct ggtgctacag gatttctgga 1200

 ctccactgtt ggaattaaag aaaaatctat ttaccttcgc ttatggaaaa 1250

 gaaaccactg taatcacagg gactaccaga atatttcaag aaatggtgca 1300

 tcttcccgaa acctgaagaa atttatagaa agcttgtcta gaaacaaggt 1350

 gttggactat cccgccatcg ttatatatgc catgattgga aatgatgtct 1400

 gcagtgggaa gagtgaccca gtcccagcca tgaccactcc tgagaaactc 1450

 tactccaacg tcatgcagac tctgaagcat ctaaattccc acctgcccaa 1500

 tggcagccat gttattttgt atggcttacc agatggaacc tttctctggg 1550

 ataatttgca caacagatat catcctctcg gccagctaaa taaagacatg 1600

 acctatgcgc agttgtactc cttcctgaac tgcctccagg tcagcccctg 1650

 ccacggctgg atgtcttcca acaagacgtt gcggactctc acttcagaga 1700

 gagcagagca actctccaac acactgaaaa aaattgcagc cagtgagaaa 1750

 tttacaaact tcaatctttt ctacatggat tttgccttcc atgaaatcat 1800

 acaggagtgg cagaagagag gcggacagcc ctggcagctc atcgagcccg 1850

 tggatggatt ccaccccaac gaggtggctt tgctgttgtt ggcggatcat 1900

 ttctggaaaa aggtgcagct ccagtggccc caaatcctgg gaaaggagaa 1950

 tccgttcaac ccccagatta aacaggtgtt tggagaccaa ggcgggcact 2000

 gagcctctca ggagcatgca cccctgggga gcacagggag gcagaggctt 2050

 gggtaaactc attccacaaa ccctatgggg gctgccacgt cacaggccca 2100

 aaggactctt cttcagcagc atctttgcaa aatgtctttc tctcaatgaa 2150

 gagcatatct ggacgactgt gcaatgctgt gtgctcccgg ggatcagtaa 2200

 cccttccgct gttcctgaaa taacctttca taaagtgctt tgggtgccat 2250

 tcca 2254

<210> 1400
<211> 575
<212> PRT
<213> Homo sapien

<400> 1400
 Met Gln Ser Pro Trp Lys Ile Leu Thr Val Ala Pro Leu Phe Leu
   1               5                  10                  15

 Leu Leu Ser Leu Gln Ser Ser Ala Ser Pro Ala Asn Asp Asp Gln
                  20                  25                  30

 Ser Arg Pro Ser Leu Ser Asn Gly His Thr Cys Val Gly Cys Val
                  35                  40                  45

 Leu Val Val Ser Val Ile Glu Gln Leu Ala Gln Val His Asn Ser
                  50                  55                  60

 Thr Val Gln Ala Ser Met Glu Arg Leu Cys Ser Tyr Leu Pro Glu
                  65                  70                  75

 Lys Leu Phe Leu Lys Thr Thr Cys Tyr Leu Val Ile Asp Lys Phe
                  80                  85                  90

 Gly Ser Asp Ile Ile Lys Leu Leu Ser Ala Asp Met Asn Ala Asp
                  95                 100                 105

 Val Val Cys His Thr Leu Glu Phe Cys Lys Gln Asn Thr Gly Gln
                 110                 115                 120

 Pro Leu Cys His Leu Tyr Pro Leu Pro Lys Glu Thr Trp Lys Phe
                 125                 130                 135

 Thr Leu Gln Lys Ala Arg Gln Ile Val Lys Lys Ser Pro Ile Leu
                 140                 145                 150

 Lys Tyr Ser Arg Ser Gly Ser Asp Ile Cys Ser Leu Pro Val Leu
                 155                 160                 165

 Ala Lys Ile Cys Gln Lys Ile Lys Leu Ala Met Glu Gln Ser Val
                 170                 175                 180

 Pro Phe Lys Asp Val Asp Ser Asp Lys Tyr Ser Val Phe Pro Thr
                 185                 190                 195

 Leu Arg Gly Tyr His Trp Arg Gly Arg Asp Cys Asn Asp Ser Asp
                 200                 205                 210

 Glu Ser Val Tyr Pro Gly Arg Arg Pro Asn Asn Trp Asp Val His
                 215                 220                 225

 Gln Asp Ser Asn Cys Asn Gly Ile Trp Gly Val Asp Pro Lys Asp
                 230                 235                 240

 Gly Val Pro Tyr Glu Lys Lys Phe Cys Glu Gly Ser Gln Pro Arg
                 245                 250                 255

 Gly Ile Ile Leu Leu Gly Asp Ser Ala Gly Ala His Phe His Ile
                 260                 265                 270

 Ser Pro Glu Trp Ile Thr Ala Ser Gln Met Ser Leu Asn Ser Phe
                 275                 280                 285

 Ile Asn Leu Pro Thr Ala Leu Thr Asn Glu Leu Asp Trp Pro Gln
                 290                 295                 300

 Leu Ser Gly Ala Thr Gly Phe Leu Asp Ser Thr Val Gly Ile Lys
                 305                 310                 315

 Glu Lys Ser Ile Tyr Leu Arg Leu Trp Lys Arg Asn His Cys Asn
                 320                 325                 330

 His Arg Asp Tyr Gln Asn Ile Ser Arg Asn Gly Ala Ser Ser Arg
                 335                 340                 345

 Asn Leu Lys Lys Phe Ile Glu Ser Leu Ser Arg Asn Lys Val Leu
                 350                 355                 360

 Asp Tyr Pro Ala Ile Val Ile Tyr Ala Met Ile Gly Asn Asp Val
                 365                 370                 375

 Cys Ser Gly Lys Ser Asp Pro Val Pro Ala Met Thr Thr Pro Glu
                 380                 385                 390

 Lys Leu Tyr Ser Asn Val Met Gln Thr Leu Lys His Leu Asn Ser
                 395                 400                 405

 His Leu Pro Asn Gly Ser His Val Ile Leu Tyr Gly Leu Pro Asp
                 410                 415                 420

 Gly Thr Phe Leu Trp Asp Asn Leu His Asn Arg Tyr His Pro Leu
                 425                 430                 435

 Gly Gln Leu Asn Lys Asp Met Thr Tyr Ala Gln Leu Tyr Ser Phe
                 440                 445                 450

 Leu Asn Cys Leu Gln Val Ser Pro Cys His Gly Trp Met Ser Ser
                 455                 460                 465

 Asn Lys Thr Leu Arg Thr Leu Thr Ser Glu Arg Ala Glu Gln Leu
                 470                 475                 480

 Ser Asn Thr Leu Lys Lys Ile Ala Ala Ser Glu Lys Phe Thr Asn
                 485                 490                 495

 Phe Asn Leu Phe Tyr Met Asp Phe Ala Phe His Glu Ile Ile Gln
                 500                 505                 510

 Glu Trp Gln Lys Arg Gly Gly Gln Pro Trp Gln Leu Ile Glu Pro
                 515                 520                 525

 Val Asp Gly Phe His Pro Asn Glu Val Ala Leu Leu Leu Leu Ala
                 530                 535                 540

 Asp His Phe Trp Lys Lys Val Gln Leu Gln Trp Pro Gln Ile Leu
                 545                 550                 555

 Gly Lys Glu Asn Pro Phe Asn Pro Gln Ile Lys Gln Val Phe Gly
                 560                 565                 570

 Asp Gln Gly Gly His
                 575

<210> 1401
<211> 1482
<212> DNA
<213> Homo sapien

<400> 1401
 cggaagcggc ggagtagagc ggagcctggc gggcgtggga acccaggccc 50

 cgccgaggcg gccaggaggt gagatggcag ctgggcaaaa tgggcacgaa 100

 gagtgggtgg gcagcgcata cctgtttgtg gagtcctcgc tggacaaggt 150

 ggtcctgtcg gatgcctacg cgcaccccca gcagaaggtg gcagtgtaca 200

 gggctctgca ggctgccttg gcagagagcg gcgggagccc ggacgtgctg 250

 cagatgctga agatccaccg cagcgacccg cagctgatcg tgcagctgcg 300

 attctgcggg cggcagccct gtggccgctt cctccgcgcc taccgcgagg 350

 gggcgctgcg cgccgcgctg cagaggagcc tggcggccgc gctcgcccag 400

 cactcggtgc cgctgcaact ggagctgcgc gccggcgccg agcggctgga 450

 cgctttgctg gcggacgagg agcgctgttt gagttgcatc ctagcccagc 500

 agcccgaccg gctccgggat gaagaactgg ctgagctgga ggatgcgctg 550

 cgaaatctga agtgcggctc gggggcccgg ggtggcgacg gggaggtcgc 600

 ttcggccccc ttgcagcccc cggtgccctc tctgtcggag gtgaagccgc 650

 cgccgccgcc gccacctgcc cagacttttc tgttccaggg tcagcctgta 700

 gtgaatcggc cgctgagcct gaaggaccaa cagacgttcg cgcgctctgt 750

 gggtctcaaa tggcgcaagg tggggcgctc actgcagcga ggctgccggg 800

 cgctgcggga cccggcgctg gactcgctgg cctacgagta cgagcgcgag 850

 ggactgtacg agcaggcctt ccagctgctg cggcgcttcg tgcaggccga 900

 gggccgccgc gccacgctgc agcgcctggt ggaggcactc gaggagaacg 950

 agctcaccag cctggcagag gacttgctgg gcctgaccga tcccaatggc 1000

 ggcctggcct agaccagggg tgcagccagc ttttggagaa cctggatggc 1050

 cttagggttc cttctgcggc tattgctgaa cccctgtcca tccacgggac 1100

 cctgaaactc cacttggcct atctgctgga cctgctgggg cagagttgat 1150

 tgccttcccc aggagccaga ccactggggg tgcatcattg gggattctgc 1200

 ctcaggtact ttgatagagt gtggggtggg ggggacctgc tttggagatc 1250

 agcctcacct tctcccatcc cagaagcggg gcttacagcc agcccttaca 1300

 gtttcactca tgaagcacct tgatctttgg tgtcctggac ttcatcctgg 1350

 gtgctgcaga tactgcagtg aagtaaaaca ggaatcaatc ttgcctgccc 1400

 ccagctcaca ctcagcgtgg gaccccgaat gttaagcaat gataataaag 1450

 tataacacgg aaaaaaaaaa aaaaaaaaaa aa 1482

<210> 1402
<211> 312
<212> PRT
<213> Homo sapien

<400> 1402
 Met Ala Ala Gly Gln Asn Gly His Glu Glu Trp Val Gly Ser Ala
   1               5                  10                  15

 Tyr Leu Phe Val Glu Ser Ser Leu Asp Lys Val Val Leu Ser Asp
                  20                  25                  30

 Ala Tyr Ala His Pro Gln Gln Lys Val Ala Val Tyr Arg Ala Leu
                  35                  40                  45

 Gln Ala Ala Leu Ala Glu Ser Gly Gly Ser Pro Asp Val Leu Gln
                  50                  55                  60

 Met Leu Lys Ile His Arg Ser Asp Pro Gln Leu Ile Val Gln Leu
                  65                  70                  75

 Arg Phe Cys Gly Arg Gln Pro Cys Gly Arg Phe Leu Arg Ala Tyr
                  80                  85                  90

 Arg Glu Gly Ala Leu Arg Ala Ala Leu Gln Arg Ser Leu Ala Ala
                  95                 100                 105

 Ala Leu Ala Gln His Ser Val Pro Leu Gln Leu Glu Leu Arg Ala
                 110                 115                 120

 Gly Ala Glu Arg Leu Asp Ala Leu Leu Ala Asp Glu Glu Arg Cys
                 125                 130                 135

 Leu Ser Cys Ile Leu Ala Gln Gln Pro Asp Arg Leu Arg Asp Glu
                 140                 145                 150

 Glu Leu Ala Glu Leu Glu Asp Ala Leu Arg Asn Leu Lys Cys Gly
                 155                 160                 165

 Ser Gly Ala Arg Gly Gly Asp Gly Glu Val Ala Ser Ala Pro Leu
                 170                 175                 180

 Gln Pro Pro Val Pro Ser Leu Ser Glu Val Lys Pro Pro Pro Pro
                 185                 190                 195

 Pro Pro Pro Ala Gln Thr Phe Leu Phe Gln Gly Gln Pro Val Val
                 200                 205                 210

 Asn Arg Pro Leu Ser Leu Lys Asp Gln Gln Thr Phe Ala Arg Ser
                 215                 220                 225

 Val Gly Leu Lys Trp Arg Lys Val Gly Arg Ser Leu Gln Arg Gly
                 230                 235                 240

 Cys Arg Ala Leu Arg Asp Pro Ala Leu Asp Ser Leu Ala Tyr Glu
                 245                 250                 255

 Tyr Glu Arg Glu Gly Leu Tyr Glu Gln Ala Phe Gln Leu Leu Arg
                 260                 265                 270

 Arg Phe Val Gln Ala Glu Gly Arg Arg Ala Thr Leu Gln Arg Leu
                 275                 280                 285

 Val Glu Ala Leu Glu Glu Asn Glu Leu Thr Ser Leu Ala Glu Asp
                 290                 295                 300

 Leu Leu Gly Leu Thr Asp Pro Asn Gly Gly Leu Ala
                 305                 310

<210> 1403
<211> 6928
<212> DNA
<213> Homo sapien

<400> 1403
 ggcgggagcg cgtgcgcccg aggacccggc cggaaggctt gcgccagctc 50

 aggatgagga caggctgggc gacccctcgc cgcccggcgg ggctcctcat 100

 gctgctcttc tggttcttcg atctcgcgga gccctctggc cgcgcagcta 150

 atgacccctt caccatcgtc catggaaata cgggcaagtg catcaagcca 200

 gtgtatggct ggatagtagc agacgactgt gatgaaactg aggacaagtt 250

 atggaagtgg gtgtcccagc atcggctctt tcatttgcac tcccaaaagt 300

 gccttggcct cgatattacc aaatcggtaa atgagctgag aatgttcagc 350

 tgtgactcca gtgccatgct gtggtggaaa tgtgagcacc actctctgta 400

 cggagctgcc cggtaccggc tggctctgaa ggatggacat ggcacagcaa 450

 tctcaaatgc atctgatgtc tggaagaaag gaggctcaga ggaaagcctt 500

 tgtgaccagc cttatcatga gatctatacc agagatggga actcttatgg 550

 gagaccttgt gaatttccat tcttaattga tgggacctgg catcatgatt 600

 gcattcttga tgaagatcat agtgggccat ggtgtgccac caccttaaat 650

 tatgaatatg accgaaagtg gggcatctgc ttaaagcctg aaaacggttg 700

 tgaagataat tgggaaaaga acgagcagtt tggaagttgc taccaattta 750

 atactcagac ggctctttct tggaaagaag cttatgtttc atgtcagaat 800

 caaggagctg atttactgag catcaacagt gctgctgaat taacttacct 850

 taaagaaaaa gaaggcattg ctaagatttt ctggattggt ttaaatcagc 900

 tatactctgc tagaggctgg gaatggtcag accacaaacc attaaacttt 950

 ctcaactggg atccagacag gcccagtgca cctactatag gtggctccag 1000

 ctgtgcaaga atggatgctg agtctggtct gtggcagagc ttttcctgtg 1050

 aagctcaact gccctatgtc tgcaggaaac cattaaataa tacagtggag 1100

 ttaacagatg tctggacata ctcagatacc cgctgtgatg caggctggct 1150

 gccaaataat ggattttgct atctgctggt aaatgaaagt aattcctggg 1200

 ataaggcaca tgcgaaatgc aaagccttca gtagtgacct aatcagcatt 1250

 cattctctag cagatgtgga ggtggttgtc acaaaactcc ataatgagga 1300

 tatcaaagaa gaagtgtgga taggccttaa gaacataaac ataccaactt 1350

 tatttcagtg gtcagatggt actgaagtta ctctaacata ttgggatgag 1400

 aatgagccaa atgttcccta caataagacg cccaactgtg tttcctactt 1450

 aggagagcta ggtcagtgga aagtccaatc atgtgaggag aaactaaaat 1500

 atgtatgcaa gagaaaggga gaaaaactga atgacgcaag ttctgataag 1550

 atgtgtcctc cagatgaggg ctggaagaga catggagaaa cctgttacaa 1600

 gatttatgag gatgaggtcc cttttggaac aaactgcaat ctgactatca 1650

 ctagcagatt tgagcaagaa tacctaaatg atttgatgaa aaagtatgat 1700

 aaatctctaa gaaaatactt ctggactggc ctgagagatg tagattcttg 1750

 tggagagtat aactgggcaa ctgttggtgg aagaaggcgg gctgtaacct 1800

 tttccaactg gaattttctt gagccagctt ccccgggcgg ctgcgtggct 1850

 atgtctactg gaaagtctgt tggaaagtgg gaggtgaagg actgcagaag 1900

 cttcaaagca ctttcaattt gcaagaaaat gagtggaccc cttgggcctg 1950

 aagaagcatc ccctaagcct gatgacccct gtcctgaagg ctggcagagt 2000

 ttccccgcaa gtctttcttg ttataaggta ttccatgcag aaagaattgt 2050

 aagaaagagg aactgggaag aagctgaacg attctgccaa gcccttggag 2100

 cacacctttc tagcttcagc catgtggatg aaataaagga atttcttcac 2150

 tttttaacgg accagttcag tggccagcat tggctgtgga ttggtttgaa 2200

 taaaaggagc ccagatttac aaggatcctg gcaatggagt gatcgtacac 2250

 cagtgtctac tattatcatg ccaaatgagt ttcagcagga ttatgacatc 2300

 agagactgtg ctgctgtcaa ggtatttcat aggccatggc gaagaggctg 2350

 gcatttctat gatgatagag aatttattta tttgaggcct tttgcttgtg 2400

 atacaaaact tgaatgggtg tgccaaattc caaaaggccg tactccaaaa 2450

 acaccagact ggtacaatcc agaccgtgct ggaattcatg gacctccact 2500

 tataattgaa ggaagtgaat attggtttgt tgctgatctt cacctaaact 2550

 atgaagaagc cgtcctgtac tgtgccagca atcacagctt tcttgcgact 2600

 ataacatctt ttgtgggact aaaagccatc aaaaacaaaa tagcaaatat 2650

 atctggtgat ggacagaagt ggtggataag aattagcgag tggccaatag 2700

 atgatcattt tacatactca cgatatccat ggcaccgctt tcctgtgaca 2750

 tttggagagg aatgcttgta catgtctgcc aagacttggc ttatcgactt 2800

 aggtaaacca acagactgta gtaccaagtt gcccttcatc tgtgaaaaat 2850

 ataatgtttc ttcgttagag aaatacagcc cagattctgc agctaaagtg 2900

 caatgttctg agcaatggat tccttttcag aataagtgtt ttctaaagat 2950

 caaacccgtg tctctcacat tttctcaagc aagcgatacc tgtcactcct 3000

 atggtggcac ccttccttca gtgttgagcc agattgaaca agactttatt 3050

 acatccttgc ttccggatat ggaagctact ttatggattg gtttgcgctg 3100

 gactgcctat gaaaagataa acaaatggac agataacaga gagctgacgt 3150

 acagtaactt tcacccatta ttggttagtg ggaggctgag aataccagaa 3200

 aatttttttg aggaagagtc tcgctaccac tgtgccctaa tactcaacct 3250

 ccaaaaatca ccgtttactg ggacgtggaa ttttacatcc tgcagtgaac 3300

 gccactttgt gtctctctgt cagaaatatt cagaagttaa aagcagacag 3350

 acgttgcaga atgcttcaga aactgtaaag tatctaaata atctgtacaa 3400

 aataatccca aagactctga cttggcacag tgctaaaagg gagtgtctga 3450

 aaagtaacat gcagctggtg agcatcacgg acccttacca gcaggcattc 3500

 ctcagtgtgc aggcgctcct tcacaactct tccttatgga tcggactctt 3550

 cagtcaagat gatgaactca actttggttg gtcagatggg aaacgtcttc 3600

 attttagtcg ctgggctgaa actaatgggc aactcgaaga ctgtgtagta 3650

 ttagacactg atggattctg gaaaacagtt gattgcaatg acaatcaacc 3700

 aggtgctatt tgctactatt caggaaatga gactgaaaaa gaggtcaaac 3750

 cagttgacag tgttaaatgt ccatctcctg ttctaaatac tccgtggata 3800

 ccatttcaga actgttgcta caatttcata ataacaaaga ataggcatat 3850

 ggcaacaaca caggatgaag ttcatactaa atgccagaaa ctgaatccaa 3900

 aatcacatat tctgagtatt cgagatgaaa aggagaataa ctttgttctt 3950

 gagcaactgc tgtacttcaa ttatatggct tcatgggtca tgttaggaat 4000

 aacttataga aataattctc ttatgtggtt tgataagacc ccactgtcat 4050

 atacacattg gagagcagga agaccaacta taaaaaatga gaagtttttg 4100

 gctggtttaa gtactgacgg cttctgggat attcaaacct ttaaagttat 4150

 tgaagaagca gtttattttc accagcacag cattcttgct tgtaaaattg 4200

 aaatggttga ctacaaagaa gaacataata ctacactgcc acagtttatg 4250

 ccatatgaag atggtattta cagtgttatt caaaaaaagg taacatggta 4300

 tgaagcatta aacatgtgtt ctcaaagtgg aggtcacttg gcaagcgttc 4350

 acaaccaaaa tggccagctc tttctggaag atattgtaaa acgtgatgga 4400

 tttccactat gggttgggct ctcaagtcat gatggaagtg aatcaagttt 4450

 tgaatggtct gatggtagta catttgacta tatcccatgg aaaggccaaa 4500

 catctcctgg aaattgtgtt ctcttggatc caaaaggaac ttggaaacat 4550

 gaaaaatgca actctgttaa ggatggtgct atttgttata aacctacaaa 4600

 atctaaaaag ctgtcccgtc ttacatattc atcaagatgt ccagcagcaa 4650

 aagagaatgg gtcacggtgg atccagtaca agggtcactg ttacaagtct 4700

 gatcaggcat tgcacagttt ttcagaggcc aaaaaattgt gttcaaaaca 4750

 tgatcactct gcaactatcg tttccataaa agatgaagat gagaataaat 4800

 ttgtgagcag actgatgagg gaaaataata acattaccat gagagtttgg 4850

 cttggattat ctcaacattc tgttgaccag tcttggagtt ggttagatgg 4900

 atcagaagtg acatttgtca aatgggaaaa taaaagtaag agtggtgttg 4950

 gaagatgtag catgttgata gcttcaaatg aaacttggaa aaaagttgaa 5000

 tgtgaacatg gttttggaag agttgtctgc aaagtgcctc tgggccctga 5050

 ttacacagca atagctatca tagttgccac actaagtatc ttagttctca 5100

 tgggcggact gatttggttc ctcttccaaa ggcaccgttt gcacctggcg 5150

 ggtttctcat cagttcgata tgcacaagga gtgaatgaag atgagattat 5200

 gcttccttct ttccatgact aaattcttct aaaagttttc taatttgcac 5250

 taatgtggtt atggagaaat tagtcactta aaatgtccca gtgtcagtat 5300

 ttactctgct ccaaagtaga actcttaaat actttttcag ttgtttagat 5350

 cttaggcatg tgctggtatc cacagttaat tccctgctaa atgccatgtt 5400

 tatcacccta attaatagaa tggaggggac tccaaagctg gaactgaagt 5450

 ccaaattgtt tgtacagtaa tatgtttaat gttcattttc tctgtatgaa 5500

 tgtgattggt aactaggata tgtatatttt aatagaattt ttaacaaaac 5550

 ttcttagaaa attaaaatag gcatattact aggtgacatg tctacttttt 5600

 aatttttaag agcatccggc caaatgcaaa attagtacct caaagtaaaa 5650

 attgaactgt aaactctatc agcattgttt caaaatagtc atttttagca 5700

 ctggggaaaa ataaacaata agacatgctt actttttaat ttttattttt 5750

 ttgagactga gtctctctct gttgcccagg ctggagtaca atggcgtgat 5800

 ctcggctcac tgcaaatctc cgcctcccag gttcaagcga ttctcctgcc 5850

 tcagcctcct gagtagctgg gattacaggc aactgccacc atgcccggct 5900

 aatttttgta tttttagtag agatggggtt tcaccatgtt ggccaggctg 5950

 gtctcgaact cgtgaccgca gtgatcctcc cgcctcggcc tcccaaagtg 6000

 ctgggattac aggcatgagc caccgcgcct ggcctctgct tactttttat 6050

 atagcaaaat gattcccctt ggcaagatgt ttcttatatt attccaaagt 6100

 tatttcatac cattattatg taaatatgaa gagttttttt ctgtttataa 6150

 ttgtttataa aacaatgact tttaaagatt tagtgcttaa cattttccca 6200

 agtgtgggaa cattattttt agattgagta ggtaccttgt agcagtgtgc 6250

 tttgcatttt ctgatgtatt acatgactgt ttcttttgta aagagaatca 6300

 actaggtatt taagactgat aattttacaa tttatatgct tcacatagca 6350

 tgtcaacttt tgactaagaa ttttgtttta cttttttaac atgtgttaaa 6400

 cagagaaagg gtccatgaag gaaagtgtat gagttgcatt tgtaaaaatg 6450

 agactttttc agtggaactc taaaccttgt gatgactact aacaaatgta 6500

 aaattatgag tgattaagaa aacattgctt tgtggttatc actttaagtt 6550

 ttgacaccta gattatagtc ttagtaatag catccactgg aaaaggtgaa 6600

 aatgttttat tcagcattta acttacattt gtactttaga gtatttttgt 6650

 ataaaatcca tagatttatt ttacatttag agtatttaca ctatgataaa 6700

 gttgtaaata attttctaag acagttttta tatagtctac agttgtcctg 6750

 atttcttatt gaatttgtta gactagttct cttgtcttgt gatctgtgta 6800

 caattttagt cactaagact ttcctccaag aactaagcca acttgatgtg 6850

 aaaagcacgg ctgtatataa tggtgatgtc ataataaagt tgttttatct 6900

 tttaagtaaa aaaaaaaaaa aaaaaaaa 6928

<210> 1404
<211> 1722
<212> PRT
<213> Homo sapien

<400> 1404
 Met Arg Thr Gly Trp Ala Thr Pro Arg Arg Pro Ala Gly Leu Leu
   1               5                  10                  15

 Met Leu Leu Phe Trp Phe Phe Asp Leu Ala Glu Pro Ser Gly Arg
                  20                  25                  30

 Ala Ala Asn Asp Pro Phe Thr Ile Val His Gly Asn Thr Gly Lys
                  35                  40                  45

 Cys Ile Lys Pro Val Tyr Gly Trp Ile Val Ala Asp Asp Cys Asp
                  50                  55                  60

 Glu Thr Glu Asp Lys Leu Trp Lys Trp Val Ser Gln His Arg Leu
                  65                  70                  75

 Phe His Leu His Ser Gln Lys Cys Leu Gly Leu Asp Ile Thr Lys
                  80                  85                  90

 Ser Val Asn Glu Leu Arg Met Phe Ser Cys Asp Ser Ser Ala Met
                  95                 100                 105

 Leu Trp Trp Lys Cys Glu His His Ser Leu Tyr Gly Ala Ala Arg
                 110                 115                 120

 Tyr Arg Leu Ala Leu Lys Asp Gly His Gly Thr Ala Ile Ser Asn
                 125                 130                 135

 Ala Ser Asp Val Trp Lys Lys Gly Gly Ser Glu Glu Ser Leu Cys
                 140                 145                 150

 Asp Gln Pro Tyr His Glu Ile Tyr Thr Arg Asp Gly Asn Ser Tyr
                 155                 160                 165

 Gly Arg Pro Cys Glu Phe Pro Phe Leu Ile Asp Gly Thr Trp His
                 170                 175                 180

 His Asp Cys Ile Leu Asp Glu Asp His Ser Gly Pro Trp Cys Ala
                 185                 190                 195

 Thr Thr Leu Asn Tyr Glu Tyr Asp Arg Lys Trp Gly Ile Cys Leu
                 200                 205                 210

 Lys Pro Glu Asn Gly Cys Glu Asp Asn Trp Glu Lys Asn Glu Gln
                 215                 220                 225

 Phe Gly Ser Cys Tyr Gln Phe Asn Thr Gln Thr Ala Leu Ser Trp
                 230                 235                 240

 Lys Glu Ala Tyr Val Ser Cys Gln Asn Gln Gly Ala Asp Leu Leu
                 245                 250                 255

 Ser Ile Asn Ser Ala Ala Glu Leu Thr Tyr Leu Lys Glu Lys Glu
                 260                 265                 270

 Gly Ile Ala Lys Ile Phe Trp Ile Gly Leu Asn Gln Leu Tyr Ser
                 275                 280                 285

 Ala Arg Gly Trp Glu Trp Ser Asp His Lys Pro Leu Asn Phe Leu
                 290                 295                 300

 Asn Trp Asp Pro Asp Arg Pro Ser Ala Pro Thr Ile Gly Gly Ser
                 305                 310                 315

 Ser Cys Ala Arg Met Asp Ala Glu Ser Gly Leu Trp Gln Ser Phe
                 320                 325                 330

 Ser Cys Glu Ala Gln Leu Pro Tyr Val Cys Arg Lys Pro Leu Asn
                 335                 340                 345

 Asn Thr Val Glu Leu Thr Asp Val Trp Thr Tyr Ser Asp Thr Arg
                 350                 355                 360

 Cys Asp Ala Gly Trp Leu Pro Asn Asn Gly Phe Cys Tyr Leu Leu
                 365                 370                 375

 Val Asn Glu Ser Asn Ser Trp Asp Lys Ala His Ala Lys Cys Lys
                 380                 385                 390

 Ala Phe Ser Ser Asp Leu Ile Ser Ile His Ser Leu Ala Asp Val
                 395                 400                 405

 Glu Val Val Val Thr Lys Leu His Asn Glu Asp Ile Lys Glu Glu
                 410                 415                 420

 Val Trp Ile Gly Leu Lys Asn Ile Asn Ile Pro Thr Leu Phe Gln
                 425                 430                 435

 Trp Ser Asp Gly Thr Glu Val Thr Leu Thr Tyr Trp Asp Glu Asn
                 440                 445                 450

 Glu Pro Asn Val Pro Tyr Asn Lys Thr Pro Asn Cys Val Ser Tyr
                 455                 460                 465

 Leu Gly Glu Leu Gly Gln Trp Lys Val Gln Ser Cys Glu Glu Lys
                 470                 475                 480

 Leu Lys Tyr Val Cys Lys Arg Lys Gly Glu Lys Leu Asn Asp Ala
                 485                 490                 495

 Ser Ser Asp Lys Met Cys Pro Pro Asp Glu Gly Trp Lys Arg His
                 500                 505                 510

 Gly Glu Thr Cys Tyr Lys Ile Tyr Glu Asp Glu Val Pro Phe Gly
                 515                 520                 525

 Thr Asn Cys Asn Leu Thr Ile Thr Ser Arg Phe Glu Gln Glu Tyr
                 530                 535                 540

 Leu Asn Asp Leu Met Lys Lys Tyr Asp Lys Ser Leu Arg Lys Tyr
                 545                 550                 555

 Phe Trp Thr Gly Leu Arg Asp Val Asp Ser Cys Gly Glu Tyr Asn
                 560                 565                 570

 Trp Ala Thr Val Gly Gly Arg Arg Arg Ala Val Thr Phe Ser Asn
                 575                 580                 585

 Trp Asn Phe Leu Glu Pro Ala Ser Pro Gly Gly Cys Val Ala Met
                 590                 595                 600

 Ser Thr Gly Lys Ser Val Gly Lys Trp Glu Val Lys Asp Cys Arg
                 605                 610                 615

 Ser Phe Lys Ala Leu Ser Ile Cys Lys Lys Met Ser Gly Pro Leu
                 620                 625                 630

 Gly Pro Glu Glu Ala Ser Pro Lys Pro Asp Asp Pro Cys Pro Glu
                 635                 640                 645

 Gly Trp Gln Ser Phe Pro Ala Ser Leu Ser Cys Tyr Lys Val Phe
                 650                 655                 660

 His Ala Glu Arg Ile Val Arg Lys Arg Asn Trp Glu Glu Ala Glu
                 665                 670                 675

 Arg Phe Cys Gln Ala Leu Gly Ala His Leu Ser Ser Phe Ser His
                 680                 685                 690

 Val Asp Glu Ile Lys Glu Phe Leu His Phe Leu Thr Asp Gln Phe
                 695                 700                 705

 Ser Gly Gln His Trp Leu Trp Ile Gly Leu Asn Lys Arg Ser Pro
                 710                 715                 720

 Asp Leu Gln Gly Ser Trp Gln Trp Ser Asp Arg Thr Pro Val Ser
                 725                 730                 735

 Thr Ile Ile Met Pro Asn Glu Phe Gln Gln Asp Tyr Asp Ile Arg
                 740                 745                 750

 Asp Cys Ala Ala Val Lys Val Phe His Arg Pro Trp Arg Arg Gly
                 755                 760                 765

 Trp His Phe Tyr Asp Asp Arg Glu Phe Ile Tyr Leu Arg Pro Phe
                 770                 775                 780

 Ala Cys Asp Thr Lys Leu Glu Trp Val Cys Gln Ile Pro Lys Gly
                 785                 790                 795

 Arg Thr Pro Lys Thr Pro Asp Trp Tyr Asn Pro Asp Arg Ala Gly
                 800                 805                 810

 Ile His Gly Pro Pro Leu Ile Ile Glu Gly Ser Glu Tyr Trp Phe
                 815                 820                 825

 Val Ala Asp Leu His Leu Asn Tyr Glu Glu Ala Val Leu Tyr Cys
                 830                 835                 840

 Ala Ser Asn His Ser Phe Leu Ala Thr Ile Thr Ser Phe Val Gly
                 845                 850                 855

 Leu Lys Ala Ile Lys Asn Lys Ile Ala Asn Ile Ser Gly Asp Gly
                 860                 865                 870

 Gln Lys Trp Trp Ile Arg Ile Ser Glu Trp Pro Ile Asp Asp His
                 875                 880                 885

 Phe Thr Tyr Ser Arg Tyr Pro Trp His Arg Phe Pro Val Thr Phe
                 890                 895                 900

 Gly Glu Glu Cys Leu Tyr Met Ser Ala Lys Thr Trp Leu Ile Asp
                 905                 910                 915

 Leu Gly Lys Pro Thr Asp Cys Ser Thr Lys Leu Pro Phe Ile Cys
                 920                 925                 930

 Glu Lys Tyr Asn Val Ser Ser Leu Glu Lys Tyr Ser Pro Asp Ser
                 935                 940                 945

 Ala Ala Lys Val Gln Cys Ser Glu Gln Trp Ile Pro Phe Gln Asn
                 950                 955                 960

 Lys Cys Phe Leu Lys Ile Lys Pro Val Ser Leu Thr Phe Ser Gln
                 965                 970                 975

 Ala Ser Asp Thr Cys His Ser Tyr Gly Gly Thr Leu Pro Ser Val
                 980                 985                 990

 Leu Ser Gln Ile Glu Gln Asp Phe Ile Thr Ser Leu Leu Pro Asp
                 995                1000                1005

 Met Glu Ala Thr Leu Trp Ile Gly Leu Arg Trp Thr Ala Tyr Glu
                1010                1015                1020

 Lys Ile Asn Lys Trp Thr Asp Asn Arg Glu Leu Thr Tyr Ser Asn
                1025                1030                1035

 Phe His Pro Leu Leu Val Ser Gly Arg Leu Arg Ile Pro Glu Asn
                1040                1045                1050

 Phe Phe Glu Glu Glu Ser Arg Tyr His Cys Ala Leu Ile Leu Asn
                1055                1060                1065

 Leu Gln Lys Ser Pro Phe Thr Gly Thr Trp Asn Phe Thr Ser Cys
                1070                1075                1080

 Ser Glu Arg His Phe Val Ser Leu Cys Gln Lys Tyr Ser Glu Val
                1085                1090                1095

 Lys Ser Arg Gln Thr Leu Gln Asn Ala Ser Glu Thr Val Lys Tyr
                1100                1105                1110

 Leu Asn Asn Leu Tyr Lys Ile Ile Pro Lys Thr Leu Thr Trp His
                1115                1120                1125

 Ser Ala Lys Arg Glu Cys Leu Lys Ser Asn Met Gln Leu Val Ser
                1130                1135                1140

 Ile Thr Asp Pro Tyr Gln Gln Ala Phe Leu Ser Val Gln Ala Leu
                1145                1150                1155

 Leu His Asn Ser Ser Leu Trp Ile Gly Leu Phe Ser Gln Asp Asp
                1160                1165                1170

 Glu Leu Asn Phe Gly Trp Ser Asp Gly Lys Arg Leu His Phe Ser
                1175                1180                1185

 Arg Trp Ala Glu Thr Asn Gly Gln Leu Glu Asp Cys Val Val Leu
                1190                1195                1200

 Asp Thr Asp Gly Phe Trp Lys Thr Val Asp Cys Asn Asp Asn Gln
                1205                1210                1215

 Pro Gly Ala Ile Cys Tyr Tyr Ser Gly Asn Glu Thr Glu Lys Glu
                1220                1225                1230

 Val Lys Pro Val Asp Ser Val Lys Cys Pro Ser Pro Val Leu Asn
                1235                1240                1245

 Thr Pro Trp Ile Pro Phe Gln Asn Cys Cys Tyr Asn Phe Ile Ile
                1250                1255                1260

 Thr Lys Asn Arg His Met Ala Thr Thr Gln Asp Glu Val His Thr
                1265                1270                1275

 Lys Cys Gln Lys Leu Asn Pro Lys Ser His Ile Leu Ser Ile Arg
                1280                1285                1290

 Asp Glu Lys Glu Asn Asn Phe Val Leu Glu Gln Leu Leu Tyr Phe
                1295                1300                1305

 Asn Tyr Met Ala Ser Trp Val Met Leu Gly Ile Thr Tyr Arg Asn
                1310                1315                1320

 Asn Ser Leu Met Trp Phe Asp Lys Thr Pro Leu Ser Tyr Thr His
                1325                1330                1335

 Trp Arg Ala Gly Arg Pro Thr Ile Lys Asn Glu Lys Phe Leu Ala
                1340                1345                1350

 Gly Leu Ser Thr Asp Gly Phe Trp Asp Ile Gln Thr Phe Lys Val
                1355                1360                1365

 Ile Glu Glu Ala Val Tyr Phe His Gln His Ser Ile Leu Ala Cys
                1370                1375                1380

 Lys Ile Glu Met Val Asp Tyr Lys Glu Glu His Asn Thr Thr Leu
                1385                1390                1395

 Pro Gln Phe Met Pro Tyr Glu Asp Gly Ile Tyr Ser Val Ile Gln
                1400                1405                1410

 Lys Lys Val Thr Trp Tyr Glu Ala Leu Asn Met Cys Ser Gln Ser
                1415                1420                1425

 Gly Gly His Leu Ala Ser Val His Asn Gln Asn Gly Gln Leu Phe
                1430                1435                1440

 Leu Glu Asp Ile Val Lys Arg Asp Gly Phe Pro Leu Trp Val Gly
                1445                1450                1455

 Leu Ser Ser His Asp Gly Ser Glu Ser Ser Phe Glu Trp Ser Asp
                1460                1465                1470

 Gly Ser Thr Phe Asp Tyr Ile Pro Trp Lys Gly Gln Thr Ser Pro
                1475                1480                1485

 Gly Asn Cys Val Leu Leu Asp Pro Lys Gly Thr Trp Lys His Glu
                1490                1495                1500

 Lys Cys Asn Ser Val Lys Asp Gly Ala Ile Cys Tyr Lys Pro Thr
                1505                1510                1515

 Lys Ser Lys Lys Leu Ser Arg Leu Thr Tyr Ser Ser Arg Cys Pro
                1520                1525                1530

 Ala Ala Lys Glu Asn Gly Ser Arg Trp Ile Gln Tyr Lys Gly His
                1535                1540                1545

 Cys Tyr Lys Ser Asp Gln Ala Leu His Ser Phe Ser Glu Ala Lys
                1550                1555                1560

 Lys Leu Cys Ser Lys His Asp His Ser Ala Thr Ile Val Ser Ile
                1565                1570                1575

 Lys Asp Glu Asp Glu Asn Lys Phe Val Ser Arg Leu Met Arg Glu
                1580                1585                1590

 Asn Asn Asn Ile Thr Met Arg Val Trp Leu Gly Leu Ser Gln His
                1595                1600                1605

 Ser Val Asp Gln Ser Trp Ser Trp Leu Asp Gly Ser Glu Val Thr
                1610                1615                1620

 Phe Val Lys Trp Glu Asn Lys Ser Lys Ser Gly Val Gly Arg Cys
                1625                1630                1635

 Ser Met Leu Ile Ala Ser Asn Glu Thr Trp Lys Lys Val Glu Cys
                1640                1645                1650

 Glu His Gly Phe Gly Arg Val Val Cys Lys Val Pro Leu Gly Pro
                1655                1660                1665

 Asp Tyr Thr Ala Ile Ala Ile Ile Val Ala Thr Leu Ser Ile Leu
                1670                1675                1680

 Val Leu Met Gly Gly Leu Ile Trp Phe Leu Phe Gln Arg His Arg
                1685                1690                1695

 Leu His Leu Ala Gly Phe Ser Ser Val Arg Tyr Ala Gln Gly Val
                1700                1705                1710

 Asn Glu Asp Glu Ile Met Leu Pro Ser Phe His Asp
                1715                1720

<210> 1405
<211> 1667
<212> DNA
<213> Homo sapien

<400> 1405
 ctgatcacag gtagcactca gattaccctg cctgctctgt gctttgctgc 50

 agaccatttg accagaacgt gtgcagctca gccagccaca gaactggaat 100

 ttttcaggag cagggggagc atggagtttg gactttgctg agcaactgaa 150

 gtggagcgca gagcttgctc gcttaggaga gagcatcatg gatggcaaac 200

 aagggggcat ggatgggagc aagcccgcgg ggccaaggga ctttcctggc 250

 atcaggcttc tttcaaaccc attgatgggc gatgctgtgt ctgattggtc 300

 tcctatgcat gaagctgcaa tccacggaca tcagctgtct ctgaggaacc 350

 tcatcagcca ggggtgggct gtgaacatca tcacggcaga tcatgtttcc 400

 ccactccatg aagcctgtct tggaggtcat ctctcttgtg tgaagatttt 450

 attaaagcat ggagctcagg tgaatggtgt gacagcagac tggcacactc 500

 cactgtttaa tgcttgtgtc agcggcagct gggattgtgt gaatttgctt 550

 ctgcagcacg gagccagcgt tcaacctgag agtgatctgg catcccccat 600

 ccatgaagct gctaggagag gccacgtgga gtgtgtcaac tctcttatag 650

 cttatggggg caacattgac cataagatca gccacctggg cactccactc 700

 tatttggctt gtgaaaacca acagagagcc tgtgtcaaga agcttctgga 750

 gtcaggagcg gacgtgaacc aagggaaagg tcaggattcc ccacttcatg 800

 cagtggccag gacagccagt gaagagctgg cctgcctgct catggatttt 850

 ggagcggaca cccaggccaa gaatgctgaa ggcaaacgtc ctgtggagct 900

 ggtgcctcca gagagcccct tggcccagct cttcttggag agagaaggtg 950

 cttctttgcc aaaacctaag ccctaatctg ttgacatccc ttggggctct 1000

 agtagaaggg cccccttctt tgatgcagtt atgccgcctt agaattcgga 1050

 agtgttttgg aatccagcag catcataaga taaccaaact cgtcctccca 1100

 gaggatctga aacagtttct cctacatctt taaatgcatc tagggaatgg 1150

 attcacaaac gatgtgaaaa cattattgag tgttgtagcc actagaattt 1200

 taaaatcaag ttggatttat agagtttgac tagttttttc gattagattt 1250

 gtatttgtta taaacttgtt tatggagttt gactaatttt ttctattcaa 1300

 tttgtatttg ttaaactcaa gccagggtgg aaagacactg catacgtttg 1350

 tattattagt tagaaggcat gaagactttt ttccctgctt ggggagtgtc 1400

 ataagttatt gttttgcata tctactgcat gccaagcact ttctgcacca 1450

 tctaatttag ccctcacagc cactgggtca agatgtccaa ttttccagag 1500

 taaggataga ggagtcaaat tcaaatacag gttttctgac attaacttat 1550

 gtgatgactt gatcgaggca ggcttttcca gcatcactgt cctggttcca 1600

 tctctgctat atgggaatga aaataaagaa acatatttct tggcttgtct 1650

 aaaaaaaaaa aaaaaaa 1667

<210> 1406
<211> 262
<212> PRT
<213> Homo sapien

<400> 1406
 Met Asp Gly Lys Gln Gly Gly Met Asp Gly Ser Lys Pro Ala Gly
   1               5                  10                  15

 Pro Arg Asp Phe Pro Gly Ile Arg Leu Leu Ser Asn Pro Leu Met
                  20                  25                  30

 Gly Asp Ala Val Ser Asp Trp Ser Pro Met His Glu Ala Ala Ile
                  35                  40                  45

 His Gly His Gln Leu Ser Leu Arg Asn Leu Ile Ser Gln Gly Trp
                  50                  55                  60

 Ala Val Asn Ile Ile Thr Ala Asp His Val Ser Pro Leu His Glu
                  65                  70                  75

 Ala Cys Leu Gly Gly His Leu Ser Cys Val Lys Ile Leu Leu Lys
                  80                  85                  90

 His Gly Ala Gln Val Asn Gly Val Thr Ala Asp Trp His Thr Pro
                  95                 100                 105

 Leu Phe Asn Ala Cys Val Ser Gly Ser Trp Asp Cys Val Asn Leu
                 110                 115                 120

 Leu Leu Gln His Gly Ala Ser Val Gln Pro Glu Ser Asp Leu Ala
                 125                 130                 135

 Ser Pro Ile His Glu Ala Ala Arg Arg Gly His Val Glu Cys Val
                 140                 145                 150

 Asn Ser Leu Ile Ala Tyr Gly Gly Asn Ile Asp His Lys Ile Ser
                 155                 160                 165

 His Leu Gly Thr Pro Leu Tyr Leu Ala Cys Glu Asn Gln Gln Arg
                 170                 175                 180

 Ala Cys Val Lys Lys Leu Leu Glu Ser Gly Ala Asp Val Asn Gln
                 185                 190                 195

 Gly Lys Gly Gln Asp Ser Pro Leu His Ala Val Ala Arg Thr Ala
                 200                 205                 210

 Ser Glu Glu Leu Ala Cys Leu Leu Met Asp Phe Gly Ala Asp Thr
                 215                 220                 225

 Gln Ala Lys Asn Ala Glu Gly Lys Arg Pro Val Glu Leu Val Pro
                 230                 235                 240

 Pro Glu Ser Pro Leu Ala Gln Leu Phe Leu Glu Arg Glu Gly Ala
                 245                 250                 255

 Ser Leu Pro Lys Pro Lys Pro
                 260

<210> 1407
<211> 885
<212> DNA
<213> Homo sapien

<400> 1407
 agcctacgca cgaaagtgac tagggaggaa ggatattata aagtgatgca 50

 aacagaaatt ccaccagcct ccatgtatca tcatgtgtca taactcagtc 100

 aagctcagtg agcattctca gcacattgcc tcaacagctt caaggtgagc 150

 cagctcaaga ctttgctctc caccaggcag aagatgacag actgtgaatt 200

 tggatatatt tacaggctgg ctcaggacta tctgcagtgc gtcctacaga 250

 taccacaacc tggatcaggt ccaagcaaaa cgtccagagt gctacaaaat 300

 gttgcgttct cagtccaaaa agaagtggaa aagaatctga agtcatgctt 350

 ggacaatgtt aatgttgtgt ccgtagacac tgccagaaca ctattcaacc 400

 aagtgatgga aaaggagttt gaagacggca tcattaactg gggaagaatt 450

 gtaaccatat ttgcatttga aggtattctc atcaagaaac ttctacgaca 500

 gcaaattgcc ccggatgtgg atacctataa ggagatttca tattttgttg 550

 cggagttcat aatgaataac acaggagaat ggataaggca aaacggaggc 600

 tgggaaaatg gctttgtaaa gaagtttgaa cctaaatctg gctggatgac 650

 ttttctagaa gttacaggaa agatctgtga aatgctatct ctcctgaagc 700

 aatactgttg accagaaagg acactccata ttgtgaaacc ggcctaattt 750

 ttctgactga tatggaaacg attgccaaca catacttcta cttttaaata 800

 aacaactttg atgatgtaac ttgaccttcc agagttatgg aaattttgtc 850

 cccatgtaat gaataaattg tatgtatttt tctct 885

<210> 1408
<211> 175
<212> PRT
<213> Homo sapien

<400> 1408
 Met Thr Asp Cys Glu Phe Gly Tyr Ile Tyr Arg Leu Ala Gln Asp
   1               5                  10                  15

 Tyr Leu Gln Cys Val Leu Gln Ile Pro Gln Pro Gly Ser Gly Pro
                  20                  25                  30

 Ser Lys Thr Ser Arg Val Leu Gln Asn Val Ala Phe Ser Val Gln
                  35                  40                  45

 Lys Glu Val Glu Lys Asn Leu Lys Ser Cys Leu Asp Asn Val Asn
                  50                  55                  60

 Val Val Ser Val Asp Thr Ala Arg Thr Leu Phe Asn Gln Val Met
                  65                  70                  75

 Glu Lys Glu Phe Glu Asp Gly Ile Ile Asn Trp Gly Arg Ile Val
                  80                  85                  90

 Thr Ile Phe Ala Phe Glu Gly Ile Leu Ile Lys Lys Leu Leu Arg
                  95                 100                 105

 Gln Gln Ile Ala Pro Asp Val Asp Thr Tyr Lys Glu Ile Ser Tyr
                 110                 115                 120

 Phe Val Ala Glu Phe Ile Met Asn Asn Thr Gly Glu Trp Ile Arg
                 125                 130                 135

 Gln Asn Gly Gly Trp Glu Asn Gly Phe Val Lys Lys Phe Glu Pro
                 140                 145                 150

 Lys Ser Gly Trp Met Thr Phe Leu Glu Val Thr Gly Lys Ile Cys
                 155                 160                 165

 Glu Met Leu Ser Leu Leu Lys Gln Tyr Cys
                 170                 175

<210> 1409
<211> 3486
<212> DNA
<213> Homo sapien

<400> 1409
 cacaacctag tccagagcct cacagtccta ctgaacctcc tgcatggggc 50

 agcagtattg tgaaagttcc gtctggtata tttgatgtca acagcaggaa 100

 aagtagcact ggtagtatat caaatgtgct gttttctact caagatccag 150

 ttgaagatgc agtctttggc gaagctacta atctcaagaa gaatggtgat 200

 agaggagaaa aaagacaaaa gcattttcct gagaggagtt gtagttttag 250

 ttctgaaagt cgagcaggaa tgttgcttaa gaagagtagt ttggattcga 300

 attcaagtga aatggctatc atgatgggag cagatgccaa gattctcaca 350

 gcagcattga catgtcctaa gacttctcta cttcatattg caagaaccca 400

 tagctttgag aatgttagct gtcacctacc tgatagtagg acttgtatgt 450

 ctgaaagcac ttggaatcct gagcacagat catctccggt gccagagatg 500

 cttgaggaaa gccaagaact ccttgagcct gtggttgatg acgtacctaa 550

 aactactgca acagtagata catatgagag tctactaagt gatagtaaca 600

 gtaatcagtc cagagacttg aaaacagtat ccaaagatct gagaaataag 650

 agaagtagtt tatatggtat tgctaaggtg gttcagaggg aagatgttga 700

 aactggacta gatcctttgt ctcttttagc cactgaatgt acaggaggaa 750

 aaactcctga ttctgaagat aagttgtttt ctccagttat tgcacgtaat 800

 ctggctgatg aaatagaaag ctatatgaac ctaaaaagtc ccctaggtag 850

 taaatcttct agtatggaat tacacagaga ggaaaacaga gagtctggca 900

 tgactactgc atttattcat gctctagaga ggagatcaag cctaccttta 950

 gatcatggtt caccagcaca ggaaaatcct gaaagtgaaa agagctcacc 1000

 tgcagtgtcc aggtctaaaa cttttactgg gcgtttcaag cagcaaaccc 1050

 cctctcgaac tcataaagaa cgttcaactt ctttgtcagc actggtgcgt 1100

 tcttcgccac atggctcgtt gggttctgta gtaaattctt tgtcagggct 1150

 aaagctggat aatatactct cagggcccaa gatagatgtc ctgaaatctg 1200

 gtatgaaaca agcagcgaca gtagccagta agatgtgggt agctgttgcg 1250

 tctgcctaca gctactcaga tgatgaggaa gaaactaata gagactacag 1300

 cttcccagct ggcctagaag accatatttt gggggagaat atatcgccta 1350

 acacaagtat ctcagggttg gtccccagtg aacttaccca gagcaacaca 1400

 agtcttggca gtagcagcag tagtggagat gtaggaaaac tgcattatcc 1450

 aacaggtgaa gttccatttc caagaggcat gaaagggcaa gactttgaaa 1500

 aatcagatca tggttcttct caaaatacca gcatgtctag catctatcag 1550

 aattgtgcaa tggaggtttt gatgtccagt tgttcacagt gtagagcttg 1600

 tggagcttta gtttatgatg aagaaattat ggctggatgg acagcagatg 1650

 actcaaattt gaatacagct tgtccattct gtaaaagcaa cttcttgcct 1700

 cttctcaata tagaattcaa agatttgaga ggttctgcaa gctttttcct 1750

 gaaaccaagt acctctggtg acagtttaca aagtggaagc attccattgg 1800

 caaatgaatc cttggagcac aaacctgtat ccagtttagc agaacctgac 1850

 ttgatcaact ttatggactt cccaaaacat aaccagatca taactgaaga 1900

 aacaggctct gcagttgaac caagtgatga aataaagaga gccagtggag 1950

 atgtccaaac tatgaaaatt tcatctgtgc ctaatagttt atcaaagcga 2000

 aatgtgtctt tgactcgaag tcacagtgtt ggaggcccat tgcagaatat 2050

 tgactttacc cagcgaccgt ttcatggcat ctcaacagtt agtcttccaa 2100

 atagtctgca ggaagttgtg gatcctttag gaaaaagacc caatcctccc 2150

 cctgtttctg tgccctactt gagtcctcta gtactccgta aagaacttga 2200

 atctttgcta gaaaatgaag gtgatcaggt gattcataca tcttctttca 2250

 tcaatcaaca tccaatcatt ttctggaacc tcgtttggta tttcagacgt 2300

 ttggaccttc ctagtaactt gccaggactt atcctcacat ctgaacattg 2350

 taatgaaggt gtacagcttc ctctgtcatc tctgtcccag gatagcaaac 2400

 ttgtgtatat tcagctgtta tgggataata tcaaccttca tcaggaacca 2450

 agagaacctc tgtatgtctc atggaggaat tttaattctg aaaagaaatc 2500

 atctctcctg tcagaggaac aacaagaaac aagcacttta gtagaaacca 2550

 tcaggcagag tattcagcac aataatgttc ttaaacccat caacctactt 2600

 tcacagcaaa tgaagccagg catgaaaaga caaagaggca tttgacaatg 2650

 aatatggaat tgcatacaat agtctgtctt cagagattct tgaaaggttg 2700

 cagaaaattg atgctccacc aagtgccagt gtcgagtggt gcaggaagtg 2750

 ttttggagcg cctctcattt aaatagagat tcactagaat gttgacacac 2800

 aaggcttggg gattagattt catctggaaa cattcaagtt ttttttttcc 2850

 aaatcgtaag aactggtgaa tacggaattg aagtaactct tggggacaat 2900

 atataatgaa ttatgattca tattgcatta ccttgaaata tgaagtgcca 2950

 tttgaatgtc ccagggctta ttaatattga agattttcaa cccctgaact 3000

 gcttttctgc ctctgtggaa aactactttg ggattcttca gtatttgtag 3050

 tagtttgata gaaataatga ggaaccatat tcattctagg cattgtttat 3100

 atttgaagtt actgagtttg aggaatggca aattaaattt gcctaacccc 3150

 caaaacaaat gaaatatctc aattataaaa gcaacatggc cgggcacggt 3200

 ggctcaggcc tgtaatccca gcactttggg aggctgagca aggtgggtgg 3250

 atcacttgag gccaggagtt cgagaccagc ctggccaaca cggtgagacc 3300

 ctgtctttac taaaaataca aaaattagcc aggcgcacca ctgtagtccc 3350

 agctactcag gctgaggcag gagaatcgct tgaactgagg cagaggctac 3400

 agtgagtgga gatcacgcca ctgcaactcc agcttgggtg acagagtgag 3450

 accgtctcaa aaaaaaaaaa aaaaaaaaaa aaaaaa 3486

<210> 1410
<211> 791
<212> PRT
<213> Homo sapien

<400> 1410
 Met Leu Leu Lys Lys Ser Ser Leu Asp Ser Asn Ser Ser Glu Met
   1               5                  10                  15

 Ala Ile Met Met Gly Ala Asp Ala Lys Ile Leu Thr Ala Ala Leu
                  20                  25                  30

 Thr Cys Pro Lys Thr Ser Leu Leu His Ile Ala Arg Thr His Ser
                  35                  40                  45

 Phe Glu Asn Val Ser Cys His Leu Pro Asp Ser Arg Thr Cys Met
                  50                  55                  60

 Ser Glu Ser Thr Trp Asn Pro Glu His Arg Ser Ser Pro Val Pro
                  65                  70                  75

 Glu Met Leu Glu Glu Ser Gln Glu Leu Leu Glu Pro Val Val Asp
                  80                  85                  90

 Asp Val Pro Lys Thr Thr Ala Thr Val Asp Thr Tyr Glu Ser Leu
                  95                 100                 105

 Leu Ser Asp Ser Asn Ser Asn Gln Ser Arg Asp Leu Lys Thr Val
                 110                 115                 120

 Ser Lys Asp Leu Arg Asn Lys Arg Ser Ser Leu Tyr Gly Ile Ala
                 125                 130                 135

 Lys Val Val Gln Arg Glu Asp Val Glu Thr Gly Leu Asp Pro Leu
                 140                 145                 150

 Ser Leu Leu Ala Thr Glu Cys Thr Gly Gly Lys Thr Pro Asp Ser
                 155                 160                 165

 Glu Asp Lys Leu Phe Ser Pro Val Ile Ala Arg Asn Leu Ala Asp
                 170                 175                 180

 Glu Ile Glu Ser Tyr Met Asn Leu Lys Ser Pro Leu Gly Ser Lys
                 185                 190                 195

 Ser Ser Ser Met Glu Leu His Arg Glu Glu Asn Arg Glu Ser Gly
                 200                 205                 210

 Met Thr Thr Ala Phe Ile His Ala Leu Glu Arg Arg Ser Ser Leu
                 215                 220                 225

 Pro Leu Asp His Gly Ser Pro Ala Gln Glu Asn Pro Glu Ser Glu
                 230                 235                 240

 Lys Ser Ser Pro Ala Val Ser Arg Ser Lys Thr Phe Thr Gly Arg
                 245                 250                 255

 Phe Lys Gln Gln Thr Pro Ser Arg Thr His Lys Glu Arg Ser Thr
                 260                 265                 270

 Ser Leu Ser Ala Leu Val Arg Ser Ser Pro His Gly Ser Leu Gly
                 275                 280                 285

 Ser Val Val Asn Ser Leu Ser Gly Leu Lys Leu Asp Asn Ile Leu
                 290                 295                 300

 Ser Gly Pro Lys Ile Asp Val Leu Lys Ser Gly Met Lys Gln Ala
                 305                 310                 315

 Ala Thr Val Ala Ser Lys Met Trp Val Ala Val Ala Ser Ala Tyr
                 320                 325                 330

 Ser Tyr Ser Asp Asp Glu Glu Glu Thr Asn Arg Asp Tyr Ser Phe
                 335                 340                 345

 Pro Ala Gly Leu Glu Asp His Ile Leu Gly Glu Asn Ile Ser Pro
                 350                 355                 360

 Asn Thr Ser Ile Ser Gly Leu Val Pro Ser Glu Leu Thr Gln Ser
                 365                 370                 375

 Asn Thr Ser Leu Gly Ser Ser Ser Ser Ser Gly Asp Val Gly Lys
                 380                 385                 390

 Leu His Tyr Pro Thr Gly Glu Val Pro Phe Pro Arg Gly Met Lys
                 395                 400                 405

 Gly Gln Asp Phe Glu Lys Ser Asp His Gly Ser Ser Gln Asn Thr
                 410                 415                 420

 Ser Met Ser Ser Ile Tyr Gln Asn Cys Ala Met Glu Val Leu Met
                 425                 430                 435

 Ser Ser Cys Ser Gln Cys Arg Ala Cys Gly Ala Leu Val Tyr Asp
                 440                 445                 450

 Glu Glu Ile Met Ala Gly Trp Thr Ala Asp Asp Ser Asn Leu Asn
                 455                 460                 465

 Thr Ala Cys Pro Phe Cys Lys Ser Asn Phe Leu Pro Leu Leu Asn
                 470                 475                 480

 Ile Glu Phe Lys Asp Leu Arg Gly Ser Ala Ser Phe Phe Leu Lys
                 485                 490                 495

 Pro Ser Thr Ser Gly Asp Ser Leu Gln Ser Gly Ser Ile Pro Leu
                 500                 505                 510

 Ala Asn Glu Ser Leu Glu His Lys Pro Val Ser Ser Leu Ala Glu
                 515                 520                 525

 Pro Asp Leu Ile Asn Phe Met Asp Phe Pro Lys His Asn Gln Ile
                 530                 535                 540

 Ile Thr Glu Glu Thr Gly Ser Ala Val Glu Pro Ser Asp Glu Ile
                 545                 550                 555

 Lys Arg Ala Ser Gly Asp Val Gln Thr Met Lys Ile Ser Ser Val
                 560                 565                 570

 Pro Asn Ser Leu Ser Lys Arg Asn Val Ser Leu Thr Arg Ser His
                 575                 580                 585

 Ser Val Gly Gly Pro Leu Gln Asn Ile Asp Phe Thr Gln Arg Pro
                 590                 595                 600

 Phe His Gly Ile Ser Thr Val Ser Leu Pro Asn Ser Leu Gln Glu
                 605                 610                 615

 Val Val Asp Pro Leu Gly Lys Arg Pro Asn Pro Pro Pro Val Ser
                 620                 625                 630

 Val Pro Tyr Leu Ser Pro Leu Val Leu Arg Lys Glu Leu Glu Ser
                 635                 640                 645

 Leu Leu Glu Asn Glu Gly Asp Gln Val Ile His Thr Ser Ser Phe
                 650                 655                 660

 Ile Asn Gln His Pro Ile Ile Phe Trp Asn Leu Val Trp Tyr Phe
                 665                 670                 675

 Arg Arg Leu Asp Leu Pro Ser Asn Leu Pro Gly Leu Ile Leu Thr
                 680                 685                 690

 Ser Glu His Cys Asn Glu Gly Val Gln Leu Pro Leu Ser Ser Leu
                 695                 700                 705

 Ser Gln Asp Ser Lys Leu Val Tyr Ile Gln Leu Leu Trp Asp Asn
                 710                 715                 720

 Ile Asn Leu His Gln Glu Pro Arg Glu Pro Leu Tyr Val Ser Trp
                 725                 730                 735

 Arg Asn Phe Asn Ser Glu Lys Lys Ser Ser Leu Leu Ser Glu Glu
                 740                 745                 750

 Gln Gln Glu Thr Ser Thr Leu Val Glu Thr Ile Arg Gln Ser Ile
                 755                 760                 765

 Gln His Asn Asn Val Leu Lys Pro Ile Asn Leu Leu Ser Gln Gln
                 770                 775                 780

 Met Lys Pro Gly Met Lys Arg Gln Arg Gly Ile
                 785                 790

<210> 1411
<211> 1960
<212> DNA
<213> Homo sapien

<400> 1411
 atgggctcgc gctgccttaa ccctcctccg cccgcccact ctgacaccac 50

 cggaaaggat tcattcggga acattcgtgg ggcggagacg ggacaggggg 100

 cctcggcctg tagcgtcacg tccgccaggg ttacctgtgg ggctgggagc 150

 gaaccgcact cgcaccgcaa ccccggcatc agtgcccagg ttggcctcgc 200

 gccgtcctac ggggcggcca gaggccgccg aaggcctctc gcgctgcagc 250

 agtctcctca ggagcgccgc catgtgggat ggaatagcac acgtgggctt 300

 ctccctgcgt cacttccggg gactgcttcc agccaatcgg cctccgccac 350

 agccagcgca gccttgcccc ttaaagtcac aggcccccta gcgcgaaatc 400

 ccacgccccc ctggacggct gcggccgcac tcgccaccag ggggcagagg 450

 ccagagaaag ggctatttcc cggacccgcc cccttcagct tgggaaagcg 500

 aaagcgtggc aggggccgga cctgggagcg gaggaggcgg gtctccatag 550

 aaacctccac ctgtttccgg ccgggctgtg agagattagg ggctgctgcg 600

 ggggccaatc tcagccagct cgcctcttcc cagcggcctc tgcgggagcg 650

 gtgggtgttg tacacaatca tcatggcggc ggccggggcc ccggatggca 700

 tggaggaacc tggcatggac acggaggccg agactgtggc tactgaggct 750

 cccgcgcggc ccgtcaactg cctggaggct gaagccgcgg cgggggcggc 800

 ggccgaggac tccggcgccg cacgaggcag cctgcagccg gccccggccc 850

 agccccctgg ggaccccgca gcccaggcct cggtcagcaa cggcgaagac 900

 gcgggcggcg gcgcgggcag ggagctggtg gacttgaaga tcatctggaa 950

 taagaccaag catgacgtga agttccccct ggacagcaca ggctccgagc 1000

 tgaaacagaa gatccactcg attacaggtc tcccgcctgc catgcagaaa 1050

 gtcatgtata agggactcgt ccccgaggat aaaacattga gagaaataaa 1100

 agtgaccagt ggggccaaga tcatggtggt tggctccacc atcaatgatg 1150

 ttttagcagt aaacacaccc aaagatgctg cgcagcagga tgcaaaggcc 1200

 gaagagaaca agaaggagcc tctctgcagg cagaaacaac acaggaaagt 1250

 gttggataaa ggaaaacctg aagatgtgat gccatctgtt aagggggccc 1300

 aggagcgcct gccaacggta ccgctgtccg gcatgtacaa taaatctgga 1350

 ggaaaagtga gactcacctt taaactagaa caagaccagc tgtggattgg 1400

 cactaaagag cggactgaga aattgcccat gggctccata aaaaatgtgg 1450

 tcagtgaacc tatcgaagga catgaagact accacatgat ggcgtttcag 1500

 ttgggcccca cggaagcctc ttactactgg gtgtactggg ttccaactca 1550

 atatgtggat gcaatcaaag acactgtgct ggggaaatgg cagtattttt 1600

 gaaagcactt tcacctctgg cccaggagac tgacccaaag tgaaggacat 1650

 tgccgggaga ggcctgcagc atccctggat ttcagagttc tggaactttg 1700

 ttcataaaaa atctatattc aatctgaggt gatgtggtga ctgaagccag 1750

 aggtgatgta ctttcaccat tagcttaatt ttaacttaaa attaccagtt 1800

 ccctttcttg cagtcagctt cataccattt ttaaagtcaa tacaatggaa 1850

 atcaataaat ctgaattccg aacatgttgt gtggaatact cttaagtgtg 1900

 tttgagagta gatctgccaa ttatgttgac aagggaatga tcaaaagctt 1950

 tgttttttta 1960

<210> 1412
<211> 533
<212> PRT
<213> Homo sapien

<400> 1412
 Met Gly Ser Arg Cys Leu Asn Pro Pro Pro Pro Ala His Ser Asp
   1               5                  10                  15

 Thr Thr Gly Lys Asp Ser Phe Gly Asn Ile Arg Gly Ala Glu Thr
                  20                  25                  30

 Gly Gln Gly Ala Ser Ala Cys Ser Val Thr Ser Ala Arg Val Thr
                  35                  40                  45

 Cys Gly Ala Gly Ser Glu Pro His Ser His Arg Asn Pro Gly Ile
                  50                  55                  60

 Ser Ala Gln Val Gly Leu Ala Pro Ser Tyr Gly Ala Ala Arg Gly
                  65                  70                  75

 Arg Arg Arg Pro Leu Ala Leu Gln Gln Ser Pro Gln Glu Arg Arg
                  80                  85                  90

 His Val Gly Trp Asn Ser Thr Arg Gly Leu Leu Pro Ala Ser Leu
                  95                 100                 105

 Pro Gly Thr Ala Ser Ser Gln Ser Ala Ser Ala Thr Ala Ser Ala
                 110                 115                 120

 Ala Leu Pro Leu Lys Val Thr Gly Pro Leu Ala Arg Asn Pro Thr
                 125                 130                 135

 Pro Pro Trp Thr Ala Ala Ala Ala Leu Ala Thr Arg Gly Gln Arg
                 140                 145                 150

 Pro Glu Lys Gly Leu Phe Pro Gly Pro Ala Pro Phe Ser Leu Gly
                 155                 160                 165

 Lys Arg Lys Arg Gly Arg Gly Arg Thr Trp Glu Arg Arg Arg Arg
                 170                 175                 180

 Val Ser Ile Glu Thr Ser Thr Cys Phe Arg Pro Gly Cys Glu Arg
                 185                 190                 195

 Leu Gly Ala Ala Ala Gly Ala Asn Leu Ser Gln Leu Ala Ser Ser
                 200                 205                 210

 Gln Arg Pro Leu Arg Glu Arg Trp Val Leu Tyr Thr Ile Ile Met
                 215                 220                 225

 Ala Ala Ala Gly Ala Pro Asp Gly Met Glu Glu Pro Gly Met Asp
                 230                 235                 240

 Thr Glu Ala Glu Thr Val Ala Thr Glu Ala Pro Ala Arg Pro Val
                 245                 250                 255

 Asn Cys Leu Glu Ala Glu Ala Ala Ala Gly Ala Ala Ala Glu Asp
                 260                 265                 270

 Ser Gly Ala Ala Arg Gly Ser Leu Gln Pro Ala Pro Ala Gln Pro
                 275                 280                 285

 Pro Gly Asp Pro Ala Ala Gln Ala Ser Val Ser Asn Gly Glu Asp
                 290                 295                 300

 Ala Gly Gly Gly Ala Gly Arg Glu Leu Val Asp Leu Lys Ile Ile
                 305                 310                 315

 Trp Asn Lys Thr Lys His Asp Val Lys Phe Pro Leu Asp Ser Thr
                 320                 325                 330

 Gly Ser Glu Leu Lys Gln Lys Ile His Ser Ile Thr Gly Leu Pro
                 335                 340                 345

 Pro Ala Met Gln Lys Val Met Tyr Lys Gly Leu Val Pro Glu Asp
                 350                 355                 360

 Lys Thr Leu Arg Glu Ile Lys Val Thr Ser Gly Ala Lys Ile Met
                 365                 370                 375

 Val Val Gly Ser Thr Ile Asn Asp Val Leu Ala Val Asn Thr Pro
                 380                 385                 390

 Lys Asp Ala Ala Gln Gln Asp Ala Lys Ala Glu Glu Asn Lys Lys
                 395                 400                 405

 Glu Pro Leu Cys Arg Gln Lys Gln His Arg Lys Val Leu Asp Lys
                 410                 415                 420

 Gly Lys Pro Glu Asp Val Met Pro Ser Val Lys Gly Ala Gln Glu
                 425                 430                 435

 Arg Leu Pro Thr Val Pro Leu Ser Gly Met Tyr Asn Lys Ser Gly
                 440                 445                 450

 Gly Lys Val Arg Leu Thr Phe Lys Leu Glu Gln Asp Gln Leu Trp
                 455                 460                 465

 Ile Gly Thr Lys Glu Arg Thr Glu Lys Leu Pro Met Gly Ser Ile
                 470                 475                 480

 Lys Asn Val Val Ser Glu Pro Ile Glu Gly His Glu Asp Tyr His
                 485                 490                 495

 Met Met Ala Phe Gln Leu Gly Pro Thr Glu Ala Ser Tyr Tyr Trp
                 500                 505                 510

 Val Tyr Trp Val Pro Thr Gln Tyr Val Asp Ala Ile Lys Asp Thr
                 515                 520                 525

 Val Leu Gly Lys Trp Gln Tyr Phe
                 530

<210> 1413
<211> 1233
<212> DNA
<213> Homo sapien

<400> 1413
 ctaaagctct cttgctgcct agcctcctgc cggcctcatc ttcgcccagc 50

 caaccccgcc tggagcccta tggccaactg cgagttcagc ccggtgtccg 100

 gggacaaacc ctgctgccgg ctctctagga gagcccaact ctgtcttggc 150

 gtcagtatcc tggtcctgat cctcgtcgtg gtgctcgcgg tggtcgtccc 200

 gaggtggcgc cagacgtgga gcggtccggg caccaccaag cgctttcccg 250

 agaccgtcct ggcgcgatgc gtcaagtaca ctgaaattca tcctgagatg 300

 agacatgtag actgccaaag tgtatgggat gctttcaagg gtgcatttat 350

 ttcaaaacat ccttgcaaca ttactgaaga agactatcag ccactaatga 400

 agttgggaac tcagaccgta ccttgcaaca agattcttct ttggagcaga 450

 ataaaagatc tggcccatca gttcacacag gtccagcggg acatgttcac 500

 cctggaggac acgctgctag gctaccttgc tgatgacctc acatggtgtg 550

 gtgaattcaa cacttccaaa ataaactatc aatcttgccc agactggaga 600

 aaggactgca gcaacaaccc tgtttcagta ttctggaaaa cggtttcccg 650

 caggtttgca gaagctgcct gtgatgtggt ccatgtgatg ctcaatggat 700

 cccgcagtaa aatctttgac aaaaacagca cttttgggag tgtggaagtc 750

 cataatttgc aaccagagaa ggttcagaca ctagaggcct gggtgataca 800

 tggtggaaga gaagattcca gagacttatg ccaggatccc accataaaag 850

 agctggaatc gattataagc aaaaggaata ttcaattttc ctgcaagaat 900

 atctacagac ctgacaagtt tcttcagtgt gtgaaaaatc ctgaggattc 950

 atcttgcaca tctgagatct gagccagtcg ctgtggttgt tttagctcct 1000

 tgactccttg tggtttatgt catcatacat gactcagcat acctgctggt 1050

 gcagagctga agattttgga gggtcctcca caataaggtc aatgccagag 1100

 acggaagcct ttttccccaa agtcttaaaa taacttatat catcagcata 1150

 cctttattgt gatctatcaa tagtcaagaa aaattattgt ataagattag 1200

 aatgaaaatt gtatgttaag ttacttcctt tag 1233

<210> 1414
<211> 300
<212> PRT
<213> Homo sapien

<400> 1414
 Met Ala Asn Cys Glu Phe Ser Pro Val Ser Gly Asp Lys Pro Cys
   1               5                  10                  15

 Cys Arg Leu Ser Arg Arg Ala Gln Leu Cys Leu Gly Val Ser Ile
                  20                  25                  30

 Leu Val Leu Ile Leu Val Val Val Leu Ala Val Val Val Pro Arg
                  35                  40                  45

 Trp Arg Gln Thr Trp Ser Gly Pro Gly Thr Thr Lys Arg Phe Pro
                  50                  55                  60

 Glu Thr Val Leu Ala Arg Cys Val Lys Tyr Thr Glu Ile His Pro
                  65                  70                  75

 Glu Met Arg His Val Asp Cys Gln Ser Val Trp Asp Ala Phe Lys
                  80                  85                  90

 Gly Ala Phe Ile Ser Lys His Pro Cys Asn Ile Thr Glu Glu Asp
                  95                 100                 105

 Tyr Gln Pro Leu Met Lys Leu Gly Thr Gln Thr Val Pro Cys Asn
                 110                 115                 120

 Lys Ile Leu Leu Trp Ser Arg Ile Lys Asp Leu Ala His Gln Phe
                 125                 130                 135

 Thr Gln Val Gln Arg Asp Met Phe Thr Leu Glu Asp Thr Leu Leu
                 140                 145                 150

 Gly Tyr Leu Ala Asp Asp Leu Thr Trp Cys Gly Glu Phe Asn Thr
                 155                 160                 165

 Ser Lys Ile Asn Tyr Gln Ser Cys Pro Asp Trp Arg Lys Asp Cys
                 170                 175                 180

 Ser Asn Asn Pro Val Ser Val Phe Trp Lys Thr Val Ser Arg Arg
                 185                 190                 195

 Phe Ala Glu Ala Ala Cys Asp Val Val His Val Met Leu Asn Gly
                 200                 205                 210

 Ser Arg Ser Lys Ile Phe Asp Lys Asn Ser Thr Phe Gly Ser Val
                 215                 220                 225

 Glu Val His Asn Leu Gln Pro Glu Lys Val Gln Thr Leu Glu Ala
                 230                 235                 240

 Trp Val Ile His Gly Gly Arg Glu Asp Ser Arg Asp Leu Cys Gln
                 245                 250                 255

 Asp Pro Thr Ile Lys Glu Leu Glu Ser Ile Ile Ser Lys Arg Asn
                 260                 265                 270

 Ile Gln Phe Ser Cys Lys Asn Ile Tyr Arg Pro Asp Lys Phe Leu
                 275                 280                 285

 Gln Cys Val Lys Asn Pro Glu Asp Ser Ser Cys Thr Ser Glu Ile
                 290                 295                 300

<210> 1415
<211> 2718
<212> DNA
<213> Homo sapien

<400> 1415
 ccgccatggg gtccctgttc cggagcgaga ccatgtgcct ggcgcagctc 50

 ttcctgcagt cgggcacggc ctacgagtgc ctcagcgccc tgggcgagaa 100

 aggcctggtc cagttccgag acctcaacca gaacgtaagt tctttccaaa 150

 gaaaatttgt tggtgaggtg aagaggtgtg aagagctaga gcgaatattg 200

 gtgtatttgg tacaggaaat taatagagct gatattcccc ttcctgaagg 250

 agaggccagc cctcctgcgc cacccctgaa acaggttcta gaaatgcagg 300

 agcagttgca gaagctcgag gttgaactga gagaagtcac taagaacaag 350

 gagaaactga ggaaaaactt gctggaactg atagagtaca ctcacatgct 400

 gagagtgaca aagacctttg tgaaacgcaa cgttgagttt gaacccactt 450

 atgaagaatt cccttcctta gagagcgatt ctttgttgga ttacagctgt 500

 atgcagaggc tgggagcaaa actgggattt gtgtctggcc taattaacca 550

 aggaaaagtg gaagcatttg aaaaaatgtt gtggagagtc tgcaaagggt 600

 acaccatcgt gtcctatgca gaactggatg aatcccttga agaccctgaa 650

 acaggggaag tcataaaatg gtatgtcttt ttaatatcct tttggggaga 700

 gcagattggc cacaaggtta agaagatatg tgattgctac cactgccacg 750

 tgtaccccta tccaaacaca gccgaggagc ggagggagat ccaggagggg 800

 ctgaacaccc gcatccagga tctctacact gtactgcaca aaaccgagga 850

 ctatttgagg caagtgctat gtaaagccgc cgagtctgtc tacagccgtg 900

 tgatccaggt gaagaaaatg aaggccatct atcacatgct gaacatgtgc 950

 agctttgacg tgaccaacaa gtgcctcatt gctgaagtct ggtgtcccga 1000

 ggcggatctg caggacctgc gccgggcact ggaggagggc tcgagagaga 1050

 gtggtgctac aatcccctca ttcatgaata taatccccac aaaagaaaca 1100

 ccccccactc ggatccgcac caacaaattc accgagggat ttcagaacat 1150

 cgtggatgct tatggagtcg gaagctacag agaagtcaat ccagctctct 1200

 ttaccatcat caccttcccg tttttatttg ctgtgatgtt tggagacttc 1250

 ggacatggct ttgtgatgtt tttatttgcc ctcttgtggg tgttaaatga 1300

 aaatcatccc agactaaatc agtcacaaga gatcatgagg atgtttttta 1350

 atggccggta catcctcctg ctgatggggc tgttctcagt gtacactggc 1400

 ctcatctaca acgactgctt ttcaaagtca gtcaacctgt tcggctctgg 1450

 gtggaacgtg tcggccatgt acagctccag ccacccaccc gcagagcata 1500

 agaagatggt gctttggaac gacagcgtcg ttagacacaa cagcattttg 1550

 cagctggatc caagcattcc tggagtgttc cgaggccctt atccccttgg 1600

 cattgatcct atttggaact tggccacaaa tcgcctcact tttctaaact 1650

 ctttcaaaat gaaaatgtcc gtgattttag gaatcattca tatgactttt 1700

 ggagtcattc tgggaatatt taaccacttg cacttcagga agaagttcaa 1750

 catttacctg gtttccatcc cggaacttct cttcatgctc tgtatctttg 1800

 gataccttat atttatgatt ttctacaagt ggctggtttt ttcagcagaa 1850

 acctccagag ttgctcccag cattctgatt gaatttatta acatgttttt 1900

 attcccagcc agtaaaacaa gtggccttta cacagggcag gagtatgtcc 1950

 agagagtgct gctggttgtc acagcattgt ctgtccctgt cctcttcttg 2000

 ggaaagccac tgtttttgtt gtggcttcac aatgggcgta gttgcttcgg 2050

 ggtgaaccgg agtggctaca cacttataag gaaagatagt gaggaagaag 2100

 tttcattgct gggaagccaa gatatagaag agggaaatca ccaggtggaa 2150

 gatggatgta gagaaatggc gtgtgaagag tttaattttg gagaaatatt 2200

 aatgacccaa gtaatccatt ccatcgagta ctgtctggga tgcatctcca 2250

 acaccgcctc ctacctgagg ctctgggcgc ttagcctggc tcacgcacag 2300

 ttgtctgatg tcctgtgggc catgctgatg cgcgtgggcc tccgcgttga 2350

 caccacctat ggcgtcttgc tactgctccc ggttatcgcg ctctttgcag 2400

 ttttgaccat tttcatcctt ctgatcatgg aagggctttc tgcgtttctt 2450

 cacgccatac gcctccactg ggtagaattt cagaacaaat tctacgttgg 2500

 tgcaggcacc aaatttgttc ctttctcatt cagtctactt tcatcaaagt 2550

 tcaataacga cgacagtgtg gcatgatcat attgctgtaa ccaacaagct 2600

 ttcagattta tggagaatga ccatgttata gactttcact tatgtcagat 2650

 ttatgatagg aaaaattcca tcttcattac tgccttatga catagccaaa 2700

 taattctgta agatatac 2718

<210> 1416
<211> 856
<212> PRT
<213> Homo sapien

<400> 1416
 Met Gly Ser Leu Phe Arg Ser Glu Thr Met Cys Leu Ala Gln Leu
   1               5                  10                  15

 Phe Leu Gln Ser Gly Thr Ala Tyr Glu Cys Leu Ser Ala Leu Gly
                  20                  25                  30

 Glu Lys Gly Leu Val Gln Phe Arg Asp Leu Asn Gln Asn Val Ser
                  35                  40                  45

 Ser Phe Gln Arg Lys Phe Val Gly Glu Val Lys Arg Cys Glu Glu
                  50                  55                  60

 Leu Glu Arg Ile Leu Val Tyr Leu Val Gln Glu Ile Asn Arg Ala
                  65                  70                  75

 Asp Ile Pro Leu Pro Glu Gly Glu Ala Ser Pro Pro Ala Pro Pro
                  80                  85                  90

 Leu Lys Gln Val Leu Glu Met Gln Glu Gln Leu Gln Lys Leu Glu
                  95                 100                 105

 Val Glu Leu Arg Glu Val Thr Lys Asn Lys Glu Lys Leu Arg Lys
                 110                 115                 120

 Asn Leu Leu Glu Leu Ile Glu Tyr Thr His Met Leu Arg Val Thr
                 125                 130                 135

 Lys Thr Phe Val Lys Arg Asn Val Glu Phe Glu Pro Thr Tyr Glu
                 140                 145                 150

 Glu Phe Pro Ser Leu Glu Ser Asp Ser Leu Leu Asp Tyr Ser Cys
                 155                 160                 165

 Met Gln Arg Leu Gly Ala Lys Leu Gly Phe Val Ser Gly Leu Ile
                 170                 175                 180

 Asn Gln Gly Lys Val Glu Ala Phe Glu Lys Met Leu Trp Arg Val
                 185                 190                 195

 Cys Lys Gly Tyr Thr Ile Val Ser Tyr Ala Glu Leu Asp Glu Ser
                 200                 205                 210

 Leu Glu Asp Pro Glu Thr Gly Glu Val Ile Lys Trp Tyr Val Phe
                 215                 220                 225

 Leu Ile Ser Phe Trp Gly Glu Gln Ile Gly His Lys Val Lys Lys
                 230                 235                 240

 Ile Cys Asp Cys Tyr His Cys His Val Tyr Pro Tyr Pro Asn Thr
                 245                 250                 255

 Ala Glu Glu Arg Arg Glu Ile Gln Glu Gly Leu Asn Thr Arg Ile
                 260                 265                 270

 Gln Asp Leu Tyr Thr Val Leu His Lys Thr Glu Asp Tyr Leu Arg
                 275                 280                 285

 Gln Val Leu Cys Lys Ala Ala Glu Ser Val Tyr Ser Arg Val Ile
                 290                 295                 300

 Gln Val Lys Lys Met Lys Ala Ile Tyr His Met Leu Asn Met Cys
                 305                 310                 315

 Ser Phe Asp Val Thr Asn Lys Cys Leu Ile Ala Glu Val Trp Cys
                 320                 325                 330

 Pro Glu Ala Asp Leu Gln Asp Leu Arg Arg Ala Leu Glu Glu Gly
                 335                 340                 345

 Ser Arg Glu Ser Gly Ala Thr Ile Pro Ser Phe Met Asn Ile Ile
                 350                 355                 360

 Pro Thr Lys Glu Thr Pro Pro Thr Arg Ile Arg Thr Asn Lys Phe
                 365                 370                 375

 Thr Glu Gly Phe Gln Asn Ile Val Asp Ala Tyr Gly Val Gly Ser
                 380                 385                 390

 Tyr Arg Glu Val Asn Pro Ala Leu Phe Thr Ile Ile Thr Phe Pro
                 395                 400                 405

 Phe Leu Phe Ala Val Met Phe Gly Asp Phe Gly His Gly Phe Val
                 410                 415                 420

 Met Phe Leu Phe Ala Leu Leu Trp Val Leu Asn Glu Asn His Pro
                 425                 430                 435

 Arg Leu Asn Gln Ser Gln Glu Ile Met Arg Met Phe Phe Asn Gly
                 440                 445                 450

 Arg Tyr Ile Leu Leu Leu Met Gly Leu Phe Ser Val Tyr Thr Gly
                 455                 460                 465

 Leu Ile Tyr Asn Asp Cys Phe Ser Lys Ser Val Asn Leu Phe Gly
                 470                 475                 480

 Ser Gly Trp Asn Val Ser Ala Met Tyr Ser Ser Ser His Pro Pro
                 485                 490                 495

 Ala Glu His Lys Lys Met Val Leu Trp Asn Asp Ser Val Val Arg
                 500                 505                 510

 His Asn Ser Ile Leu Gln Leu Asp Pro Ser Ile Pro Gly Val Phe
                 515                 520                 525

 Arg Gly Pro Tyr Pro Leu Gly Ile Asp Pro Ile Trp Asn Leu Ala
                 530                 535                 540

 Thr Asn Arg Leu Thr Phe Leu Asn Ser Phe Lys Met Lys Met Ser
                 545                 550                 555

 Val Ile Leu Gly Ile Ile His Met Thr Phe Gly Val Ile Leu Gly
                 560                 565                 570

 Ile Phe Asn His Leu His Phe Arg Lys Lys Phe Asn Ile Tyr Leu
                 575                 580                 585

 Val Ser Ile Pro Glu Leu Leu Phe Met Leu Cys Ile Phe Gly Tyr
                 590                 595                 600

 Leu Ile Phe Met Ile Phe Tyr Lys Trp Leu Val Phe Ser Ala Glu
                 605                 610                 615

 Thr Ser Arg Val Ala Pro Ser Ile Leu Ile Glu Phe Ile Asn Met
                 620                 625                 630

 Phe Leu Phe Pro Ala Ser Lys Thr Ser Gly Leu Tyr Thr Gly Gln
                 635                 640                 645

 Glu Tyr Val Gln Arg Val Leu Leu Val Val Thr Ala Leu Ser Val
                 650                 655                 660

 Pro Val Leu Phe Leu Gly Lys Pro Leu Phe Leu Leu Trp Leu His
                 665                 670                 675

 Asn Gly Arg Ser Cys Phe Gly Val Asn Arg Ser Gly Tyr Thr Leu
                 680                 685                 690

 Ile Arg Lys Asp Ser Glu Glu Glu Val Ser Leu Leu Gly Ser Gln
                 695                 700                 705

 Asp Ile Glu Glu Gly Asn His Gln Val Glu Asp Gly Cys Arg Glu
                 710                 715                 720

 Met Ala Cys Glu Glu Phe Asn Phe Gly Glu Ile Leu Met Thr Gln
                 725                 730                 735

 Val Ile His Ser Ile Glu Tyr Cys Leu Gly Cys Ile Ser Asn Thr
                 740                 745                 750

 Ala Ser Tyr Leu Arg Leu Trp Ala Leu Ser Leu Ala His Ala Gln
                 755                 760                 765

 Leu Ser Asp Val Leu Trp Ala Met Leu Met Arg Val Gly Leu Arg
                 770                 775                 780

 Val Asp Thr Thr Tyr Gly Val Leu Leu Leu Leu Pro Val Ile Ala
                 785                 790                 795

 Leu Phe Ala Val Leu Thr Ile Phe Ile Leu Leu Ile Met Glu Gly
                 800                 805                 810

 Leu Ser Ala Phe Leu His Ala Ile Arg Leu His Trp Val Glu Phe
                 815                 820                 825

 Gln Asn Lys Phe Tyr Val Gly Ala Gly Thr Lys Phe Val Pro Phe
                 830                 835                 840

 Ser Phe Ser Leu Leu Ser Ser Lys Phe Asn Asn Asp Asp Ser Val
                 845                 850                 855

 Ala


<210> 1417
<211> 3429
<212> DNA
<213> Homo sapien

<400> 1417
 ggctggaagc cggaagcgag caaagtggag ccgactcgaa ctccaccggc 50

 acgagggcgg aaaagaaagc ctcagaacgt tcgctcgctg cgtccccagc 100

 cggggccgag ccctccgcga cgccacccgg gccatggggg ccgcacgcag 150

 cccgccgtcc gctgtcccgg ggcccctgct ggggctgctc ctgctgctcc 200

 tgggcgtgct ggccccgggt ggcgcctccc tgcgactcct ggaccaccgg 250

 gcgctggtct gctcccagcc ggggctaaac tgcacggtca agaatagtac 300

 ctgcctggat gacagctgga ttcaccctcg aaacctgacc ccctcctccc 350

 caaaggacct gcagatccag ctgcactttg cccacaccca acaaggagac 400

 ctgttccccg tggctcacat cgaatggaca ctgcagacag acgccagcat 450

 cctgtacctc gagggtgcag agttatctgt cctgcagctg aacaccaatg 500

 aacgtttgtg cgtcaggttt gagtttctgt ccaaactgag gcatcaccac 550

 aggcggtggc gttttacctt cagccacttt gtggttgacc ctgaccagga 600

 atatgaggtg accgttcacc acctgcccaa gcccatccct gatggggacc 650

 caaaccacca gtccaagaat ttccttgtgc ctgactgtga gcacgccagg 700

 atgaaggtaa ccacgccatg catgagctca ggcagcctgt gggaccccaa 750

 catcaccgtg gagaccctgg aggcccacca gctgcgtgtg agcttcaccc 800

 tgtggaacga atctacccat taccagatcc tgctgaccag ttttccgcac 850

 atggagaacc acagttgctt tgagcacatg caccacatac ctgcgcccag 900

 accagaagag ttccaccagc gatccaacgt cacactcact ctacgcaacc 950

 ttaaagggtg ctgtcgccac caagtgcaga tccagccctt cttcagcagc 1000

 tgcctcaatg actgcctcag acactccgcg actgtttcct gcccagaaat 1050

 gccagacact ccagaaccaa ttccggacta catgcccctg tgggtgtact 1100

 ggttcatcac gggcatctcc atcctgctgg tgggctccgt catcctgctc 1150

 atcgtctgca tgacctggag gctagctggg cctggaagtg aaaaatacag 1200

 tgatgacacc aaatacaccg atggcctgcc tgcggctgac ctgatccccc 1250

 caccgctgaa gcccaggaag gtctggatca tctactcagc cgaccacccc 1300

 ctctacgtgg acgtggtcct gaaattcgcc cagttcctgc tcaccgcctg 1350

 cggcacggaa gtggccctgg acctgctgga agagcaggcc atctcggagg 1400

 caggagtcat gacctgggtg ggccgtcaga agcaggagat ggtggagagc 1450

 aactctaaga tcatcgtcct gtgctcccgc ggcacgcgcg ccaagtggca 1500

 ggcgctcctg ggccgggggg cgcctgtgcg gctgcgctgc gaccacggaa 1550

 agcccgtggg ggacctgttc actgcagcca tgaacatgat cctcccggac 1600

 ttcaagaggc cagcctgctt cggcacctac gtagtctgct acttcagcga 1650

 ggtcagctgt gacggcgacg tccccgacct gttcggcgcg gcgccgcggt 1700

 acccgctcat ggacaggttc gaggaggtgt acttccgcat ccaggacctg 1750

 gagatgttcc agccgggccg catgcaccgc gtaggggagc tgtcggggga 1800

 caactacctg cggagcccgg gcggcaggca gctccgcgcc gccctggaca 1850

 ggttccggga ctggcaggtc cgctgtcccg actggttcga atgtgagaac 1900

 ctctactcag cagatgacca ggatgccccg tccctggacg aagaggtgtt 1950

 tgaggagcca ctgctgcctc cgggaaccgg catcgtgaag cgggcgcccc 2000

 tggtgcgcga gcctggctcc caggcctgcc tggccataga cccgctggtc 2050

 ggggaggaag gaggagcagc agtggcaaag ctggaacctc acctgcagcc 2100

 ccggggtcag ccagcgccgc agcccctcca caccctggtg ctcgccgcag 2150

 aggagggggc cctggtggcc gcggtggagc ctgggcccct ggctgacggt 2200

 gccgcagtcc ggctggcact ggcgggggag ggcgaggcct gcccgctgct 2250

 gggcagcccg ggcgctgggc gaaatagcgt cctcttcctc cccgtggacc 2300

 ccgaggactc gccccttggc agcagcaccc ccatggcgtc tcctgacctc 2350

 cttccagagg acgtgaggga gcacctcgaa ggcttgatgc tctcgctctt 2400

 cgagcagagt ctgagctgcc aggcccaggg gggctgcagt agacccgcca 2450

 tggtcctcac agacccacac acgccctacg aggaggagca gcggcagtca 2500

 gtgcagtctg accagggcta catctccagg agctccccgc agccccccga 2550

 gggactcacg gaaatggagg aagaggagga agaggagcag gacccaggga 2600

 agccggccct gccactctct cccgaggacc tggagagcct gaggagcctc 2650

 cagcggcagc tgcttttccg ccagctgcag aagaactcgg gctgggacac 2700

 gatggggtca gagtcagagg ggcccagtgc atgagggcgg ctccccaggg 2750

 accgcccaga tcccagcttt gagagaggag tgtgtgtgca cgtattcatc 2800

 tgtgtgtaca tgtctgcatg tgtatatgtt cgtgtgtgaa atgtaggctt 2850

 taaaatgtaa atgtctggat tttaatccca ggcatccctc ctaacttttc 2900

 tttgtgcagc ggtctggtta tcgtctatcc ccaggggaat ccacacagcc 2950

 cgctcccagg agctaatggt agagcgtcct tgaggctcca ttattcgttc 3000

 attcagcatt tattgtgcac ctactatgtg gcgggcattt gggataccaa 3050

 gataaattgc atgcggcatg gccccagcca tgaaggaact taaccgctag 3100

 tgccgaggac acgttaaacg aacaggatgg gccgggcacg gtggctcacg 3150

 cctgtaatcc cagcacactg ggaggccgag gcaggtggat cactctgagg 3200

 tcaggagttt gagccagcct ggccaacatg gtgaaacccc atctccacta 3250

 aaaatagaaa aattagccgg gcatggtgac acatgcctgt agtcctagct 3300

 acttgggagg ctgaggcagg agaattgctt gaatctggga ggcagaggtt 3350

 gcagtgagcc gagattgtgc cattgcactg cagcctggat gacagagcga 3400

 gactctatct caaaaaaaaa aaaaaaaaa 3429

<210> 1418
<211> 866
<212> PRT
<213> Homo sapien

<400> 1418
 Met Gly Ala Ala Arg Ser Pro Pro Ser Ala Val Pro Gly Pro Leu
   1               5                  10                  15

 Leu Gly Leu Leu Leu Leu Leu Leu Gly Val Leu Ala Pro Gly Gly
                  20                  25                  30

 Ala Ser Leu Arg Leu Leu Asp His Arg Ala Leu Val Cys Ser Gln
                  35                  40                  45

 Pro Gly Leu Asn Cys Thr Val Lys Asn Ser Thr Cys Leu Asp Asp
                  50                  55                  60

 Ser Trp Ile His Pro Arg Asn Leu Thr Pro Ser Ser Pro Lys Asp
                  65                  70                  75

 Leu Gln Ile Gln Leu His Phe Ala His Thr Gln Gln Gly Asp Leu
                  80                  85                  90

 Phe Pro Val Ala His Ile Glu Trp Thr Leu Gln Thr Asp Ala Ser
                  95                 100                 105

 Ile Leu Tyr Leu Glu Gly Ala Glu Leu Ser Val Leu Gln Leu Asn
                 110                 115                 120

 Thr Asn Glu Arg Leu Cys Val Arg Phe Glu Phe Leu Ser Lys Leu
                 125                 130                 135

 Arg His His His Arg Arg Trp Arg Phe Thr Phe Ser His Phe Val
                 140                 145                 150

 Val Asp Pro Asp Gln Glu Tyr Glu Val Thr Val His His Leu Pro
                 155                 160                 165

 Lys Pro Ile Pro Asp Gly Asp Pro Asn His Gln Ser Lys Asn Phe
                 170                 175                 180

 Leu Val Pro Asp Cys Glu His Ala Arg Met Lys Val Thr Thr Pro
                 185                 190                 195

 Cys Met Ser Ser Gly Ser Leu Trp Asp Pro Asn Ile Thr Val Glu
                 200                 205                 210

 Thr Leu Glu Ala His Gln Leu Arg Val Ser Phe Thr Leu Trp Asn
                 215                 220                 225

 Glu Ser Thr His Tyr Gln Ile Leu Leu Thr Ser Phe Pro His Met
                 230                 235                 240

 Glu Asn His Ser Cys Phe Glu His Met His His Ile Pro Ala Pro
                 245                 250                 255

 Arg Pro Glu Glu Phe His Gln Arg Ser Asn Val Thr Leu Thr Leu
                 260                 265                 270

 Arg Asn Leu Lys Gly Cys Cys Arg His Gln Val Gln Ile Gln Pro
                 275                 280                 285

 Phe Phe Ser Ser Cys Leu Asn Asp Cys Leu Arg His Ser Ala Thr
                 290                 295                 300

 Val Ser Cys Pro Glu Met Pro Asp Thr Pro Glu Pro Ile Pro Asp
                 305                 310                 315

 Tyr Met Pro Leu Trp Val Tyr Trp Phe Ile Thr Gly Ile Ser Ile
                 320                 325                 330

 Leu Leu Val Gly Ser Val Ile Leu Leu Ile Val Cys Met Thr Trp
                 335                 340                 345

 Arg Leu Ala Gly Pro Gly Ser Glu Lys Tyr Ser Asp Asp Thr Lys
                 350                 355                 360

 Tyr Thr Asp Gly Leu Pro Ala Ala Asp Leu Ile Pro Pro Pro Leu
                 365                 370                 375

 Lys Pro Arg Lys Val Trp Ile Ile Tyr Ser Ala Asp His Pro Leu
                 380                 385                 390

 Tyr Val Asp Val Val Leu Lys Phe Ala Gln Phe Leu Leu Thr Ala
                 395                 400                 405

 Cys Gly Thr Glu Val Ala Leu Asp Leu Leu Glu Glu Gln Ala Ile
                 410                 415                 420

 Ser Glu Ala Gly Val Met Thr Trp Val Gly Arg Gln Lys Gln Glu
                 425                 430                 435

 Met Val Glu Ser Asn Ser Lys Ile Ile Val Leu Cys Ser Arg Gly
                 440                 445                 450

 Thr Arg Ala Lys Trp Gln Ala Leu Leu Gly Arg Gly Ala Pro Val
                 455                 460                 465

 Arg Leu Arg Cys Asp His Gly Lys Pro Val Gly Asp Leu Phe Thr
                 470                 475                 480

 Ala Ala Met Asn Met Ile Leu Pro Asp Phe Lys Arg Pro Ala Cys
                 485                 490                 495

 Phe Gly Thr Tyr Val Val Cys Tyr Phe Ser Glu Val Ser Cys Asp
                 500                 505                 510

 Gly Asp Val Pro Asp Leu Phe Gly Ala Ala Pro Arg Tyr Pro Leu
                 515                 520                 525

 Met Asp Arg Phe Glu Glu Val Tyr Phe Arg Ile Gln Asp Leu Glu
                 530                 535                 540

 Met Phe Gln Pro Gly Arg Met His Arg Val Gly Glu Leu Ser Gly
                 545                 550                 555

 Asp Asn Tyr Leu Arg Ser Pro Gly Gly Arg Gln Leu Arg Ala Ala
                 560                 565                 570

 Leu Asp Arg Phe Arg Asp Trp Gln Val Arg Cys Pro Asp Trp Phe
                 575                 580                 585

 Glu Cys Glu Asn Leu Tyr Ser Ala Asp Asp Gln Asp Ala Pro Ser
                 590                 595                 600

 Leu Asp Glu Glu Val Phe Glu Glu Pro Leu Leu Pro Pro Gly Thr
                 605                 610                 615

 Gly Ile Val Lys Arg Ala Pro Leu Val Arg Glu Pro Gly Ser Gln
                 620                 625                 630

 Ala Cys Leu Ala Ile Asp Pro Leu Val Gly Glu Glu Gly Gly Ala
                 635                 640                 645

 Ala Val Ala Lys Leu Glu Pro His Leu Gln Pro Arg Gly Gln Pro
                 650                 655                 660

 Ala Pro Gln Pro Leu His Thr Leu Val Leu Ala Ala Glu Glu Gly
                 665                 670                 675

 Ala Leu Val Ala Ala Val Glu Pro Gly Pro Leu Ala Asp Gly Ala
                 680                 685                 690

 Ala Val Arg Leu Ala Leu Ala Gly Glu Gly Glu Ala Cys Pro Leu
                 695                 700                 705

 Leu Gly Ser Pro Gly Ala Gly Arg Asn Ser Val Leu Phe Leu Pro
                 710                 715                 720

 Val Asp Pro Glu Asp Ser Pro Leu Gly Ser Ser Thr Pro Met Ala
                 725                 730                 735

 Ser Pro Asp Leu Leu Pro Glu Asp Val Arg Glu His Leu Glu Gly
                 740                 745                 750

 Leu Met Leu Ser Leu Phe Glu Gln Ser Leu Ser Cys Gln Ala Gln
                 755                 760                 765

 Gly Gly Cys Ser Arg Pro Ala Met Val Leu Thr Asp Pro His Thr
                 770                 775                 780

 Pro Tyr Glu Glu Glu Gln Arg Gln Ser Val Gln Ser Asp Gln Gly
                 785                 790                 795

 Tyr Ile Ser Arg Ser Ser Pro Gln Pro Pro Glu Gly Leu Thr Glu
                 800                 805                 810

 Met Glu Glu Glu Glu Glu Glu Glu Gln Asp Pro Gly Lys Pro Ala
                 815                 820                 825

 Leu Pro Leu Ser Pro Glu Asp Leu Glu Ser Leu Arg Ser Leu Gln
                 830                 835                 840

 Arg Gln Leu Leu Phe Arg Gln Leu Gln Lys Asn Ser Gly Trp Asp
                 845                 850                 855

 Thr Met Gly Ser Glu Ser Glu Gly Pro Ser Ala
                 860                 865

<210> 1419
<211> 2798
<212> DNA
<213> Homo sapien

<400> 1419
 cgttgctgtc gctctgcacg cacctatgtg gaaactaaag cccagagaga 50

 aagtctgact tgccccacag ccagtgagtg actgcagcag caccagaatc 100

 tggtctgttt cctgtttggc tcttctacca ctacggcttg ggatctcggg 150

 catggtggct ttgccaatgg tccttgtttt gctgctggtc ctgagcagag 200

 gtgagagtga attggacgcc aagatcccat ccacagggga tgccacagaa 250

 tggcggaatc ctcacctgtc catgctgggg tcctgccagc cagccccctc 300

 ctgccagaag tgcatcctct cacaccccag ctgtgcatgg tgcaagcaac 350

 tgaacttcac cgcgtcggga gaggcggagg cgcggcgctg cgcccgacga 400

 gaggagctgc tggctcgagg ctgcccgctg gaggagctgg aggagccccg 450

 cggccagcag gaggtgctgc aggaccagcc gctcagccag ggcgcccgcg 500

 gagagggtgc cacccagctg gcgccgcagc gggtccgggt cacgctgcgg 550

 cctggggagc cccagcagct ccaggtccgc ttccttcgtg ctgagggata 600

 cccggtggac ctgtactacc ttatggacct gagctactcc atgaaggacg 650

 acctggaacg cgtgcgccag ctcgggcacg ctctgctggt ccggctgcag 700

 gaagtcaccc attctgtgcg cattggtttt ggttcctttg tggacaaaac 750

 ggtgctgccc tttgtgagca cagtaccctc caaactgcgc cacccctgcc 800

 ccacccggct ggagcgctgc cagtcaccat tcagctttca ccatgtgctg 850

 tccctgacgg gggacgcaca agccttcgag cgggaggtgg ggcgccagag 900

 tgtgtccggc aatctggact cgcctgaagg tggcttcgat gccattctgc 950

 aggctgcact ctgccaggag cagattggct ggagaaatgt gtcccggctg 1000

 ctggtgttca cttcagacga cacattccat acagctgggg acgggaagtt 1050

 gggcggcatt ttcatgccca gtgatgggca ctgccacttg gacagcaatg 1100

 gcctctacag tcgcagcaca gagtttgact acccttctgt gggtcaggta 1150

 gcccaggccc tctctgcagc aaatatccag cccatctttg ctgtcaccag 1200

 tgccgcactg cctgtctacc aggagctgag taaactgatt cctaagtctg 1250

 cagttgggga gctgagtgag gactccagca acgtggtaca gctcatcatg 1300

 gatgcttata atagcctgtc ttccaccgtg acccttgaac actcttcact 1350

 ccctcctggg gtccacattt cttacgaatc ccagtgtgag ggtcctgaga 1400

 agagggaggg taaggctgag gatcgaggac agtgcaacca cgtccgaatc 1450

 aaccagacgg tgactttctg ggtttctctc caagccaccc actgcctccc 1500

 agagccccat ctcctgaggc tccgggccct tggcttctca gaggagctga 1550

 ttgtggagtt gcacacgctg tgtgactgta attgcagtga cacccagccc 1600

 caggctcccc actgcagtga tggccaggga cacctacaat gtggtgtatg 1650

 cagctgtgcc cctggccgcc taggtcggct ctgtgagtgc tctgtggcag 1700

 agctgtcctc cccagacctg gaatctgggt gccgggctcc caatggcaca 1750

 gggcccctgt gcagtggaaa gggtcactgt caatgtggac gctgcagctg 1800

 cagtggacag agctctgggc atctgtgcga gtgtgacgat gccagctgtg 1850

 agcgacatga gggcatcctc tgcggaggct ttggtcgctg ccaatgtgga 1900

 gtatgtcact gtcatgccaa ccgcacgggc agagcatgcg aatgcagtgg 1950

 ggacatggac agttgcatca gtcccgaggg agggctctgc agtgggcatg 2000

 gacgctgcaa atgcaaccgc tgccagtgct tggacggcta ctatggtgct 2050

 ctatgcgacc aatgcccagg ctgcaagaca ccatgcgaga gacaccggga 2100

 ctgtgcagag tgtggggcct tcaggactgg cccactggcc accaactgca 2150

 gtacagcttg tgcccatacc aatgtgaccc tggccttggc ccctatcttg 2200

 gatgatggct ggtgcaaaga gcggaccctg gacaaccagc tgttcttctt 2250

 cttggtggag gatgacgcca gaggcacggt cgtgctcaga gtgagacccc 2300

 aagaaaaggg agcagaccac acgcaggcca ttgtgctggg ctgcgtaggg 2350

 ggcatcgtgg cagtggggct ggggctggtc ctggcttacc ggctctcggt 2400

 ggaaatctat gaccgccggg aatacagtcg ctttgagaag gagcagcaac 2450

 aactcaactg gaagcaggac agtaatcctc tctacaaaag tgccatcacg 2500

 accaccatca atcctcgctt tcaagaggca gacagtccca ctctctgaag 2550

 gagggaggga cacttaccca aggctcttct ccttggagga cagtgggaac 2600

 tggagggtga gaggaagggt gggtctgtaa gaccttggta ggggactaat 2650

 tcactggcga ggtgcggcca ccaccctact tcattttcag agtgacaccc 2700

 aagagggctg cttcccatgc ctgcaacctt gcatccatct gggctacccc 2750

 acccaagtat acaataaagt cttacctcag aaaaaaaaaa aaaaaaaa 2798

<210> 1420
<211> 798
<212> PRT
<213> Homo sapien

<400> 1420
 Met Val Ala Leu Pro Met Val Leu Val Leu Leu Leu Val Leu Ser
   1               5                  10                  15

 Arg Gly Glu Ser Glu Leu Asp Ala Lys Ile Pro Ser Thr Gly Asp
                  20                  25                  30

 Ala Thr Glu Trp Arg Asn Pro His Leu Ser Met Leu Gly Ser Cys
                  35                  40                  45

 Gln Pro Ala Pro Ser Cys Gln Lys Cys Ile Leu Ser His Pro Ser
                  50                  55                  60

 Cys Ala Trp Cys Lys Gln Leu Asn Phe Thr Ala Ser Gly Glu Ala
                  65                  70                  75

 Glu Ala Arg Arg Cys Ala Arg Arg Glu Glu Leu Leu Ala Arg Gly
                  80                  85                  90

 Cys Pro Leu Glu Glu Leu Glu Glu Pro Arg Gly Gln Gln Glu Val
                  95                 100                 105

 Leu Gln Asp Gln Pro Leu Ser Gln Gly Ala Arg Gly Glu Gly Ala
                 110                 115                 120

 Thr Gln Leu Ala Pro Gln Arg Val Arg Val Thr Leu Arg Pro Gly
                 125                 130                 135

 Glu Pro Gln Gln Leu Gln Val Arg Phe Leu Arg Ala Glu Gly Tyr
                 140                 145                 150

 Pro Val Asp Leu Tyr Tyr Leu Met Asp Leu Ser Tyr Ser Met Lys
                 155                 160                 165

 Asp Asp Leu Glu Arg Val Arg Gln Leu Gly His Ala Leu Leu Val
                 170                 175                 180

 Arg Leu Gln Glu Val Thr His Ser Val Arg Ile Gly Phe Gly Ser
                 185                 190                 195

 Phe Val Asp Lys Thr Val Leu Pro Phe Val Ser Thr Val Pro Ser
                 200                 205                 210

 Lys Leu Arg His Pro Cys Pro Thr Arg Leu Glu Arg Cys Gln Ser
                 215                 220                 225

 Pro Phe Ser Phe His His Val Leu Ser Leu Thr Gly Asp Ala Gln
                 230                 235                 240

 Ala Phe Glu Arg Glu Val Gly Arg Gln Ser Val Ser Gly Asn Leu
                 245                 250                 255

 Asp Ser Pro Glu Gly Gly Phe Asp Ala Ile Leu Gln Ala Ala Leu
                 260                 265                 270

 Cys Gln Glu Gln Ile Gly Trp Arg Asn Val Ser Arg Leu Leu Val
                 275                 280                 285

 Phe Thr Ser Asp Asp Thr Phe His Thr Ala Gly Asp Gly Lys Leu
                 290                 295                 300

 Gly Gly Ile Phe Met Pro Ser Asp Gly His Cys His Leu Asp Ser
                 305                 310                 315

 Asn Gly Leu Tyr Ser Arg Ser Thr Glu Phe Asp Tyr Pro Ser Val
                 320                 325                 330

 Gly Gln Val Ala Gln Ala Leu Ser Ala Ala Asn Ile Gln Pro Ile
                 335                 340                 345

 Phe Ala Val Thr Ser Ala Ala Leu Pro Val Tyr Gln Glu Leu Ser
                 350                 355                 360

 Lys Leu Ile Pro Lys Ser Ala Val Gly Glu Leu Ser Glu Asp Ser
                 365                 370                 375

 Ser Asn Val Val Gln Leu Ile Met Asp Ala Tyr Asn Ser Leu Ser
                 380                 385                 390

 Ser Thr Val Thr Leu Glu His Ser Ser Leu Pro Pro Gly Val His
                 395                 400                 405

 Ile Ser Tyr Glu Ser Gln Cys Glu Gly Pro Glu Lys Arg Glu Gly
                 410                 415                 420

 Lys Ala Glu Asp Arg Gly Gln Cys Asn His Val Arg Ile Asn Gln
                 425                 430                 435

 Thr Val Thr Phe Trp Val Ser Leu Gln Ala Thr His Cys Leu Pro
                 440                 445                 450

 Glu Pro His Leu Leu Arg Leu Arg Ala Leu Gly Phe Ser Glu Glu
                 455                 460                 465

 Leu Ile Val Glu Leu His Thr Leu Cys Asp Cys Asn Cys Ser Asp
                 470                 475                 480

 Thr Gln Pro Gln Ala Pro His Cys Ser Asp Gly Gln Gly His Leu
                 485                 490                 495

 Gln Cys Gly Val Cys Ser Cys Ala Pro Gly Arg Leu Gly Arg Leu
                 500                 505                 510

 Cys Glu Cys Ser Val Ala Glu Leu Ser Ser Pro Asp Leu Glu Ser
                 515                 520                 525

 Gly Cys Arg Ala Pro Asn Gly Thr Gly Pro Leu Cys Ser Gly Lys
                 530                 535                 540

 Gly His Cys Gln Cys Gly Arg Cys Ser Cys Ser Gly Gln Ser Ser
                 545                 550                 555

 Gly His Leu Cys Glu Cys Asp Asp Ala Ser Cys Glu Arg His Glu
                 560                 565                 570

 Gly Ile Leu Cys Gly Gly Phe Gly Arg Cys Gln Cys Gly Val Cys
                 575                 580                 585

 His Cys His Ala Asn Arg Thr Gly Arg Ala Cys Glu Cys Ser Gly
                 590                 595                 600

 Asp Met Asp Ser Cys Ile Ser Pro Glu Gly Gly Leu Cys Ser Gly
                 605                 610                 615

 His Gly Arg Cys Lys Cys Asn Arg Cys Gln Cys Leu Asp Gly Tyr
                 620                 625                 630

 Tyr Gly Ala Leu Cys Asp Gln Cys Pro Gly Cys Lys Thr Pro Cys
                 635                 640                 645

 Glu Arg His Arg Asp Cys Ala Glu Cys Gly Ala Phe Arg Thr Gly
                 650                 655                 660

 Pro Leu Ala Thr Asn Cys Ser Thr Ala Cys Ala His Thr Asn Val
                 665                 670                 675

 Thr Leu Ala Leu Ala Pro Ile Leu Asp Asp Gly Trp Cys Lys Glu
                 680                 685                 690

 Arg Thr Leu Asp Asn Gln Leu Phe Phe Phe Leu Val Glu Asp Asp
                 695                 700                 705

 Ala Arg Gly Thr Val Val Leu Arg Val Arg Pro Gln Glu Lys Gly
                 710                 715                 720

 Ala Asp His Thr Gln Ala Ile Val Leu Gly Cys Val Gly Gly Ile
                 725                 730                 735

 Val Ala Val Gly Leu Gly Leu Val Leu Ala Tyr Arg Leu Ser Val
                 740                 745                 750

 Glu Ile Tyr Asp Arg Arg Glu Tyr Ser Arg Phe Glu Lys Glu Gln
                 755                 760                 765

 Gln Gln Leu Asn Trp Lys Gln Asp Ser Asn Pro Leu Tyr Lys Ser
                 770                 775                 780

 Ala Ile Thr Thr Thr Ile Asn Pro Arg Phe Gln Glu Ala Asp Ser
                 785                 790                 795

 Pro Thr Leu


<210> 1421
<211> 1681
<212> DNA
<213> Homo sapien

<400> 1421
 ggcacgagga tacctcctca tcaactctga catagtgtgc gaacaggaca 50

 tctacgagtg gactaagatc aatggccggc ggcgggtgcc gcgcgggggg 100

 cgggcggcgc ggagtaggtg gcggcggcca tggccgaggc gtcgccgcat 150

 cccggacggt acttctgcca ctgctgctcc gtggagatcg tcccgcgcct 200

 gccggattat atctgtccaa gatgcgagtc tggttttatc gaggagcttc 250

 cggaagagac caggagcaca gaaaatggtt ctgccccctc cacagctccc 300

 acagaccaga gccggccacc gctggagcac gtggaccagc acctgttcac 350

 gctgccgcag ggctacggac agtttgcttt cggcatcttc gatgacagct 400

 tcgagatccc cacgttccct cctggggcgc aggctgacga cggcagggac 450

 cctgagagcc ggcgggagag agaccatccg tcccggcacc ggtacggcgc 500

 ccgacagccc cgcgcccgcc tcaccacgcg gcgggccacc ggccggcacg 550

 aaggcgtccc cacgctggaa gggatcatcc agcagctcgt caacggcatc 600

 atcacgcccg ccaccatccc cagcctgggc ccctggggag tcctgcactc 650

 aaaccctatg gactacgcct ggggggccaa cggcctggat gccatcatca 700

 cacagctcct caatcagttt gaaaacacag gccccccacc ggcagataaa 750

 gagaaaatcc aggccctccc caccgtcccc gtcactgagg agcacgtagg 800

 ctccgggctc gagtgccctg tgtgcaagga cgactacgcg ctgggtgagc 850

 gtgtgcggca gctgccctgc aaccacctgt tccacgacgg ctgcatcgtg 900

 ccctggctgg agcagcacga cagctgcccc gtctgccgaa aaagcctcac 950

 gggacagaac acggccacga acccccctgg cctcactggg gtgagcttct 1000

 cctcctcgtc gtcatcgtcc tcctccagct cgcccagcaa cgagaacgcc 1050

 acaagcaact cgtgagccca cgtcggccgt cgggaaagca cggggccttt 1100

 cccacccacc ctcagccagc gccacacggc acccacagac tgggtgcccc 1150

 ggcggcgcca cgcttggctg gtcagcgctg caggtcccgc ctgttccagg 1200

 gcaggacccg ggcccggccc accggccccc tggcttggga aggcgtgggc 1250

 cacatggtcc cctctggggc gtccccagcc tccccgtcct ctgtctaacc 1300

 tcaccctcta aacgttcagc ggtggaaaga tttttataat tttaaattat 1350

 tactgctttg aaataaacgg acgtttgagc tcacgtggcg gccatgcatg 1400

 gtttgtggcg gaagacgggg cccagcggct cccccagcgc tgaagcacgg 1450

 ggttcagcgg ctcccccagt gctgcaggtg ccgccaggac gggccacgtg 1500

 ggcccccagc ctccccctcg gccgcctcca cgacccggag taggggggct 1550

 cgggaccatg aggatgacca gcaaaattca agaacaaaac tgctccaaca 1600

 gactttttta aaggaaaaaa tatgtgtatc ttgaaagcta tttaaaatac 1650

 actacttaca aagaaaaaaa aaaaaaaaaa a 1681

<210> 1422
<211> 311
<212> PRT
<213> Homo sapien

<400> 1422
 Met Ala Glu Ala Ser Pro His Pro Gly Arg Tyr Phe Cys His Cys
   1               5                  10                  15

 Cys Ser Val Glu Ile Val Pro Arg Leu Pro Asp Tyr Ile Cys Pro
                  20                  25                  30

 Arg Cys Glu Ser Gly Phe Ile Glu Glu Leu Pro Glu Glu Thr Arg
                  35                  40                  45

 Ser Thr Glu Asn Gly Ser Ala Pro Ser Thr Ala Pro Thr Asp Gln
                  50                  55                  60

 Ser Arg Pro Pro Leu Glu His Val Asp Gln His Leu Phe Thr Leu
                  65                  70                  75

 Pro Gln Gly Tyr Gly Gln Phe Ala Phe Gly Ile Phe Asp Asp Ser
                  80                  85                  90

 Phe Glu Ile Pro Thr Phe Pro Pro Gly Ala Gln Ala Asp Asp Gly
                  95                 100                 105

 Arg Asp Pro Glu Ser Arg Arg Glu Arg Asp His Pro Ser Arg His
                 110                 115                 120

 Arg Tyr Gly Ala Arg Gln Pro Arg Ala Arg Leu Thr Thr Arg Arg
                 125                 130                 135

 Ala Thr Gly Arg His Glu Gly Val Pro Thr Leu Glu Gly Ile Ile
                 140                 145                 150

 Gln Gln Leu Val Asn Gly Ile Ile Thr Pro Ala Thr Ile Pro Ser
                 155                 160                 165

 Leu Gly Pro Trp Gly Val Leu His Ser Asn Pro Met Asp Tyr Ala
                 170                 175                 180

 Trp Gly Ala Asn Gly Leu Asp Ala Ile Ile Thr Gln Leu Leu Asn
                 185                 190                 195

 Gln Phe Glu Asn Thr Gly Pro Pro Pro Ala Asp Lys Glu Lys Ile
                 200                 205                 210

 Gln Ala Leu Pro Thr Val Pro Val Thr Glu Glu His Val Gly Ser
                 215                 220                 225

 Gly Leu Glu Cys Pro Val Cys Lys Asp Asp Tyr Ala Leu Gly Glu
                 230                 235                 240

 Arg Val Arg Gln Leu Pro Cys Asn His Leu Phe His Asp Gly Cys
                 245                 250                 255

 Ile Val Pro Trp Leu Glu Gln His Asp Ser Cys Pro Val Cys Arg
                 260                 265                 270

 Lys Ser Leu Thr Gly Gln Asn Thr Ala Thr Asn Pro Pro Gly Leu
                 275                 280                 285

 Thr Gly Val Ser Phe Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser
                 290                 295                 300

 Ser Pro Ser Asn Glu Asn Ala Thr Ser Asn Ser
                 305                 310

<210> 1423
<211> 2343
<212> DNA
<213> Homo sapien

<400> 1423
 atacgactac acctgctccg gagcccgcgg cggtacctgc agcggaggag 50

 ctctgtcttc cccttcatct cacgcgagcc cggcgtcccg ccgcgtgcgc 100

 cccggcgcag cccgccagtc cgcccggagc ccgcccagtc gccgcgctgc 150

 acgcccgggg tgaaccctct gccctcgctg ggacagaggg ccccgcagcc 200

 gtcatgcttt ccgccatcta cacagtcctg gcgggactgc tgttcctgcc 250

 gctcctggtg aacctctgct gcccatactt cttccaggac ataggctact 300

 tcttgaaggt ggccgccgtg ggccggaggg tgcgcagcta cgggcagcgg 350

 cggccggcgc gcaccatcct gcgggcgttc ctggagaaag cgcgccagac 400

 gccacacaag ccttttctgc tcttccgcga cgagactctc acctacgcgc 450

 aggtggaccg gcgcagcaat caagtggccc gggcgctgca cgaccacctc 500

 ggcctgcgcc agggagactg cgtggcgctc cttatgggta acgagccggc 550

 ctacgtgtgg ctgtggctgg ggctggtgaa gctgggctgt gccatggcgt 600

 gcctcaatta caacatccgc gcgaagtccc tgctgcactg cttccagtgc 650

 tgcggggcga aggtgctgct ggtgtcgcca gaactacaag cagctgtcga 700

 agagatactg ccaagcctta aaaaagatga tgtgtccatc tattatgtga 750

 gcagaacttc taacacagat gggattgact ctttcctgga caaagtggat 800

 gaagtatcaa ctgaacctat cccagagtca tggaggtctg aagtcacttt 850

 ttccactcct gccttataca tttatacttc tggaaccaca ggtcttccaa 900

 aagcagccat gatcactcat cagcgcatat ggtatggaac tggcctcact 950

 tttgtaagcg gattgaaggc agatgatgtc atctatatca ctctgccctt 1000

 ttaccacagt gctgcactac tgattggcat tcacggatgt attgtggctg 1050

 gtgctactct tgccttgcgg actaaatttt cagccagcca gttttgggat 1100

 gactgcagaa aatacaacgt cactgtcatt cagtatatcg gtgaactgct 1150

 tcggtattta tgcaactcac cacagaaacc aaatgaccgt gatcataaag 1200

 tgagactggc actgggaaat ggcttacgag gagatgtgtg gagacaattt 1250

 gtcaagagat ttggggacat atgcatctat gagttctatg ctgccactga 1300

 aggcaatatt ggatttatga attatgcgag aaaagttggt gctgttggaa 1350

 gagtaaacta cctacagaaa aaaatcataa cttatgacct gattaaatat 1400

 gatgtggaga aagatgaacc tgtccgtgat gaaaatggat attgcgtcag 1450

 agttcccaaa ggtgaagttg gacttctggt ttgcaaaatc acacaactta 1500

 caccatttaa tggctatgct ggagcaaagg ctcagacaga gaagaaaaaa 1550

 ctgagagatg tctttaagaa aggagacctc tatttcaaca gtggagatct 1600

 cttaatggtt gaccatgaaa atttcatcta tttccacgac agagttggag 1650

 atacattccg gtggaaaggg gaaaatgtgg ccaccactga agttgctgat 1700

 acagttggac tggttgattt tgtccaagaa gtaaatgttt atggagtgca 1750

 tgtgccagat catgagggtc gcattggcat ggcctccatc aaaatgaaag 1800

 aaaaccatga atttgatgga aagaaactct ttcagcacat tgctgattac 1850

 ctacctagtt atgcaaggcc ccggtttcta agaatacagg acaccattga 1900

 gatcactgga acttttaaac accgcaaaat gaccctggtg gaggagggct 1950

 ttaaccctgc tgtcatcaaa gatgccttgt atttcttgga tgacacagca 2000

 aaaatgtatg tgcctatgac tgaggacatc tataatgcca taagtgctaa 2050

 aaccctgaaa ctctgaatat tcccaggagg ataactcaac atttccagaa 2100

 agaaactgaa tggacagcca cttgatataa tccaacttta atttgattga 2150

 agattgtgag gaaattttgt aggaaatttg catacccgta aagggagact 2200

 tttttaaata acagttgagt ctttgcaagt aaaaagattt agagattatt 2250

 atttttcagt gtgcacctac tgtttgtatt tgcaaactga gcttgttgga 2300

 gggaaggcat tattttttaa aatacttagt aaattaaatg aac 2343

<210> 1424
<211> 620
<212> PRT
<213> Homo sapien

<400> 1424
 Met Leu Ser Ala Ile Tyr Thr Val Leu Ala Gly Leu Leu Phe Leu
   1               5                  10                  15

 Pro Leu Leu Val Asn Leu Cys Cys Pro Tyr Phe Phe Gln Asp Ile
                  20                  25                  30

 Gly Tyr Phe Leu Lys Val Ala Ala Val Gly Arg Arg Val Arg Ser
                  35                  40                  45

 Tyr Gly Gln Arg Arg Pro Ala Arg Thr Ile Leu Arg Ala Phe Leu
                  50                  55                  60

 Glu Lys Ala Arg Gln Thr Pro His Lys Pro Phe Leu Leu Phe Arg
                  65                  70                  75

 Asp Glu Thr Leu Thr Tyr Ala Gln Val Asp Arg Arg Ser Asn Gln
                  80                  85                  90

 Val Ala Arg Ala Leu His Asp His Leu Gly Leu Arg Gln Gly Asp
                  95                 100                 105

 Cys Val Ala Leu Leu Met Gly Asn Glu Pro Ala Tyr Val Trp Leu
                 110                 115                 120

 Trp Leu Gly Leu Val Lys Leu Gly Cys Ala Met Ala Cys Leu Asn
                 125                 130                 135

 Tyr Asn Ile Arg Ala Lys Ser Leu Leu His Cys Phe Gln Cys Cys
                 140                 145                 150

 Gly Ala Lys Val Leu Leu Val Ser Pro Glu Leu Gln Ala Ala Val
                 155                 160                 165

 Glu Glu Ile Leu Pro Ser Leu Lys Lys Asp Asp Val Ser Ile Tyr
                 170                 175                 180

 Tyr Val Ser Arg Thr Ser Asn Thr Asp Gly Ile Asp Ser Phe Leu
                 185                 190                 195

 Asp Lys Val Asp Glu Val Ser Thr Glu Pro Ile Pro Glu Ser Trp
                 200                 205                 210

 Arg Ser Glu Val Thr Phe Ser Thr Pro Ala Leu Tyr Ile Tyr Thr
                 215                 220                 225

 Ser Gly Thr Thr Gly Leu Pro Lys Ala Ala Met Ile Thr His Gln
                 230                 235                 240

 Arg Ile Trp Tyr Gly Thr Gly Leu Thr Phe Val Ser Gly Leu Lys
                 245                 250                 255

 Ala Asp Asp Val Ile Tyr Ile Thr Leu Pro Phe Tyr His Ser Ala
                 260                 265                 270

 Ala Leu Leu Ile Gly Ile His Gly Cys Ile Val Ala Gly Ala Thr
                 275                 280                 285

 Leu Ala Leu Arg Thr Lys Phe Ser Ala Ser Gln Phe Trp Asp Asp
                 290                 295                 300

 Cys Arg Lys Tyr Asn Val Thr Val Ile Gln Tyr Ile Gly Glu Leu
                 305                 310                 315

 Leu Arg Tyr Leu Cys Asn Ser Pro Gln Lys Pro Asn Asp Arg Asp
                 320                 325                 330

 His Lys Val Arg Leu Ala Leu Gly Asn Gly Leu Arg Gly Asp Val
                 335                 340                 345

 Trp Arg Gln Phe Val Lys Arg Phe Gly Asp Ile Cys Ile Tyr Glu
                 350                 355                 360

 Phe Tyr Ala Ala Thr Glu Gly Asn Ile Gly Phe Met Asn Tyr Ala
                 365                 370                 375

 Arg Lys Val Gly Ala Val Gly Arg Val Asn Tyr Leu Gln Lys Lys
                 380                 385                 390

 Ile Ile Thr Tyr Asp Leu Ile Lys Tyr Asp Val Glu Lys Asp Glu
                 395                 400                 405

 Pro Val Arg Asp Glu Asn Gly Tyr Cys Val Arg Val Pro Lys Gly
                 410                 415                 420

 Glu Val Gly Leu Leu Val Cys Lys Ile Thr Gln Leu Thr Pro Phe
                 425                 430                 435

 Asn Gly Tyr Ala Gly Ala Lys Ala Gln Thr Glu Lys Lys Lys Leu
                 440                 445                 450

 Arg Asp Val Phe Lys Lys Gly Asp Leu Tyr Phe Asn Ser Gly Asp
                 455                 460                 465

 Leu Leu Met Val Asp His Glu Asn Phe Ile Tyr Phe His Asp Arg
                 470                 475                 480

 Val Gly Asp Thr Phe Arg Trp Lys Gly Glu Asn Val Ala Thr Thr
                 485                 490                 495

 Glu Val Ala Asp Thr Val Gly Leu Val Asp Phe Val Gln Glu Val
                 500                 505                 510

 Asn Val Tyr Gly Val His Val Pro Asp His Glu Gly Arg Ile Gly
                 515                 520                 525

 Met Ala Ser Ile Lys Met Lys Glu Asn His Glu Phe Asp Gly Lys
                 530                 535                 540

 Lys Leu Phe Gln His Ile Ala Asp Tyr Leu Pro Ser Tyr Ala Arg
                 545                 550                 555

 Pro Arg Phe Leu Arg Ile Gln Asp Thr Ile Glu Ile Thr Gly Thr
                 560                 565                 570

 Phe Lys His Arg Lys Met Thr Leu Val Glu Glu Gly Phe Asn Pro
                 575                 580                 585

 Ala Val Ile Lys Asp Ala Leu Tyr Phe Leu Asp Asp Thr Ala Lys
                 590                 595                 600

 Met Tyr Val Pro Met Thr Glu Asp Ile Tyr Asn Ala Ile Ser Ala
                 605                 610                 615

 Lys Thr Leu Lys Leu
                 620

<210> 1425
<211> 2343
<212> DNA
<213> Homo sapien

<400> 1425
 atacgactac acctgctccg gagcccgcgg cggtacctgc agcggaggag 50

 ctctgtcttc cccttcatct cacgcgagcc cggcgtcccg ccgcgtgcgc 100

 cccggcgcag cccgccagtc cgcccggagc ccgcccagtc gccgcgctgc 150

 acgcccgggg tgaaccctct gccctcgctg ggacagaggg ccccgcagcc 200

 gtcatgcttt ccgccatcta cacagtcctg gcgggactgc tgttcctgcc 250

 gctcctggtg aacctctgct gcccatactt cttccaggac ataggctact 300

 tcttgaaggt ggccgccgtg ggccggaggg tgcgcagcta cgggcagcgg 350

 cggccggcgc gcaccatcct gcgggcgttc ctggagaaag cgcgccagac 400

 gccacacaag ccttttctgc tcttccgcga cgagactctc acctacgcgc 450

 aggtggaccg gcgcagcaat caagtggccc gggcgctgca cgaccacctc 500

 ggcctgcgcc agggagactg cgtggcgctc cttatgggta acgagccggc 550

 ctacgtgtgg ctgtggctgg ggctggtgaa gctgggctgt gccatggcgt 600

 gcctcaatta caacatccgc gcgaagtccc tgctgcactg cttccagtgc 650

 tgcggggcga aggtgctgct ggtgtcgcca gaactacaag cagctgtcga 700

 agagatactg ccaagcctta aaaaagatga tgtgtccatc tattatgtga 750

 gcagaacttc taacacagat gggattgact ctttcctgga caaagtggat 800

 gaagtatcaa ctgaacctat cccagagtca tggaggtctg aagtcacttt 850

 ttccactcct gccttataca tttatacttc tggaaccaca ggtcttccaa 900

 aagcagccat gatcactcat cagcgcatat ggtatggaac tggcctcact 950

 tttgtaagcg gattgaaggc agatgatgtc atctatatca ctctgccctt 1000

 ttaccacagt gctgcactac tgattggcat tcacggatgt attgtggctg 1050

 gtgctactct tgccttgcgg actaaatttt cagccagcca gttttgggat 1100

 gactgcagaa aatacaacgt cactgtcatt cagtatatcg gtgaactgct 1150

 tcggtattta tgcaactcac cacagaaacc aaatgaccgt gatcataaag 1200

 tgagactggc actgggaaat ggcttacgag gagatgtgtg gagacaattt 1250

 gtcaagagat ttggggacat atgcatctat gagttctatg ctgccactga 1300

 aggcaatatt ggatttatga attatgcgag aaaagttggt gctgttggaa 1350

 gagtaaacta cctacagaaa aaaatcataa cttatgacct gattaaatat 1400

 gatgtggaga aagatgaacc tgtccgtgat gaaaatggat attgcgtcag 1450

 agttcccaaa ggtgaagttg gacttctggt ttgcaaaatc acacaactta 1500

 caccatttaa tggctatgct ggagcaaagg ctcagacaga gaagaaaaaa 1550

 ctgagagatg tctttaagaa aggagacctc tatttcaaca gtggagatct 1600

 cttaatggtt gaccatgaaa atttcatcta tttccacgac agagttggag 1650

 atacattccg gtggaaaggg gaaaatgtgg ccaccactga agttgctgat 1700

 acagttggac tggttgattt tgtccaagaa gtaaatgttt atggagtgca 1750

 tgtgccagat catgagggtc gcattggcat ggcctccatc aaaatgaaag 1800

 aaaaccatga atttgatgga aagaaactct ttcagcacat tgctgattac 1850

 ctacctagtt atgcaaggcc ccggtttcta agaatacagg acaccattga 1900

 gatcactgga acttttaaac accgcaaaat gaccctggtg gaggagggct 1950

 ttaaccctgc tgtcatcaaa gatgccttgt atttcttgga tgacacagca 2000

 aaaatgtatg tgcctatgac tgaggacatc tataatgcca taagtgctaa 2050

 aaccctgaaa ctctgaatat tcccaggagg ataactcaac atttccagaa 2100

 agaaactgaa tggacagcca cttgatataa tccaacttta atttgattga 2150

 agattgtgag gaaattttgt aggaaatttg catacccgta aagggagact 2200

 tttttaaata acagttgagt ctttgcaagt aaaaagattt agagattatt 2250

 atttttcagt gtgcacctac tgtttgtatt tgcaaactga gcttgttgga 2300

 gggaaggcat tattttttaa aatacttagt aaattaaatg aac 2343

<210> 1426
<211> 620
<212> PRT
<213> Homo sapien

<400> 1426
 Met Leu Ser Ala Ile Tyr Thr Val Leu Ala Gly Leu Leu Phe Leu
   1               5                  10                  15

 Pro Leu Leu Val Asn Leu Cys Cys Pro Tyr Phe Phe Gln Asp Ile
                  20                  25                  30

 Gly Tyr Phe Leu Lys Val Ala Ala Val Gly Arg Arg Val Arg Ser
                  35                  40                  45

 Tyr Gly Gln Arg Arg Pro Ala Arg Thr Ile Leu Arg Ala Phe Leu
                  50                  55                  60

 Glu Lys Ala Arg Gln Thr Pro His Lys Pro Phe Leu Leu Phe Arg
                  65                  70                  75

 Asp Glu Thr Leu Thr Tyr Ala Gln Val Asp Arg Arg Ser Asn Gln
                  80                  85                  90

 Val Ala Arg Ala Leu His Asp His Leu Gly Leu Arg Gln Gly Asp
                  95                 100                 105

 Cys Val Ala Leu Leu Met Gly Asn Glu Pro Ala Tyr Val Trp Leu
                 110                 115                 120

 Trp Leu Gly Leu Val Lys Leu Gly Cys Ala Met Ala Cys Leu Asn
                 125                 130                 135

 Tyr Asn Ile Arg Ala Lys Ser Leu Leu His Cys Phe Gln Cys Cys
                 140                 145                 150

 Gly Ala Lys Val Leu Leu Val Ser Pro Glu Leu Gln Ala Ala Val
                 155                 160                 165

 Glu Glu Ile Leu Pro Ser Leu Lys Lys Asp Asp Val Ser Ile Tyr
                 170                 175                 180

 Tyr Val Ser Arg Thr Ser Asn Thr Asp Gly Ile Asp Ser Phe Leu
                 185                 190                 195

 Asp Lys Val Asp Glu Val Ser Thr Glu Pro Ile Pro Glu Ser Trp
                 200                 205                 210

 Arg Ser Glu Val Thr Phe Ser Thr Pro Ala Leu Tyr Ile Tyr Thr
                 215                 220                 225

 Ser Gly Thr Thr Gly Leu Pro Lys Ala Ala Met Ile Thr His Gln
                 230                 235                 240

 Arg Ile Trp Tyr Gly Thr Gly Leu Thr Phe Val Ser Gly Leu Lys
                 245                 250                 255

 Ala Asp Asp Val Ile Tyr Ile Thr Leu Pro Phe Tyr His Ser Ala
                 260                 265                 270

 Ala Leu Leu Ile Gly Ile His Gly Cys Ile Val Ala Gly Ala Thr
                 275                 280                 285

 Leu Ala Leu Arg Thr Lys Phe Ser Ala Ser Gln Phe Trp Asp Asp
                 290                 295                 300

 Cys Arg Lys Tyr Asn Val Thr Val Ile Gln Tyr Ile Gly Glu Leu
                 305                 310                 315

 Leu Arg Tyr Leu Cys Asn Ser Pro Gln Lys Pro Asn Asp Arg Asp
                 320                 325                 330

 His Lys Val Arg Leu Ala Leu Gly Asn Gly Leu Arg Gly Asp Val
                 335                 340                 345

 Trp Arg Gln Phe Val Lys Arg Phe Gly Asp Ile Cys Ile Tyr Glu
                 350                 355                 360

 Phe Tyr Ala Ala Thr Glu Gly Asn Ile Gly Phe Met Asn Tyr Ala
                 365                 370                 375

 Arg Lys Val Gly Ala Val Gly Arg Val Asn Tyr Leu Gln Lys Lys
                 380                 385                 390

 Ile Ile Thr Tyr Asp Leu Ile Lys Tyr Asp Val Glu Lys Asp Glu
                 395                 400                 405

 Pro Val Arg Asp Glu Asn Gly Tyr Cys Val Arg Val Pro Lys Gly
                 410                 415                 420

 Glu Val Gly Leu Leu Val Cys Lys Ile Thr Gln Leu Thr Pro Phe
                 425                 430                 435

 Asn Gly Tyr Ala Gly Ala Lys Ala Gln Thr Glu Lys Lys Lys Leu
                 440                 445                 450

 Arg Asp Val Phe Lys Lys Gly Asp Leu Tyr Phe Asn Ser Gly Asp
                 455                 460                 465

 Leu Leu Met Val Asp His Glu Asn Phe Ile Tyr Phe His Asp Arg
                 470                 475                 480

 Val Gly Asp Thr Phe Arg Trp Lys Gly Glu Asn Val Ala Thr Thr
                 485                 490                 495

 Glu Val Ala Asp Thr Val Gly Leu Val Asp Phe Val Gln Glu Val
                 500                 505                 510

 Asn Val Tyr Gly Val His Val Pro Asp His Glu Gly Arg Ile Gly
                 515                 520                 525

 Met Ala Ser Ile Lys Met Lys Glu Asn His Glu Phe Asp Gly Lys
                 530                 535                 540

 Lys Leu Phe Gln His Ile Ala Asp Tyr Leu Pro Ser Tyr Ala Arg
                 545                 550                 555

 Pro Arg Phe Leu Arg Ile Gln Asp Thr Ile Glu Ile Thr Gly Thr
                 560                 565                 570

 Phe Lys His Arg Lys Met Thr Leu Val Glu Glu Gly Phe Asn Pro
                 575                 580                 585

 Ala Val Ile Lys Asp Ala Leu Tyr Phe Leu Asp Asp Thr Ala Lys
                 590                 595                 600

 Met Tyr Val Pro Met Thr Glu Asp Ile Tyr Asn Ala Ile Ser Ala
                 605                 610                 615

 Lys Thr Leu Lys Leu
                 620

<210> 1427
<211> 2821
<212> DNA
<213> Homo sapien

<400> 1427
 gaaaaaagaa aatgtcagag gaatttgaag ccaatactat ggattctctg 50

 gtagacatgc catttgctac tgtagatatt caggatgact gtggaatcac 100

 tgatgaacct caaataaatt tgaagagaag tcaagaaaat gaatgggtca 150

 agagtgatca agtaaagaag aggaaaaaaa agagaaaaga ttatcaaccc 200

 aactatttcc tgtccattcc aatcaccaac aaagagatta taaaaggaat 250

 taagatcctg cagaatgcaa taatacaaca agatgagcga ctggccaaag 300

 caatggtcag tgatggttcc tttcatatta ccctgctggt gatgcaatta 350

 ttaaatgaag atgaagtaaa cattggtatt gatgctcttt tggaattgaa 400

 accattcata gaagaactcc tccagggaaa acatttgact ttgccctttc 450

 aagggattgg tacttttgga aatcaggttg gatttgtgaa gctggcagaa 500

 ggagatcatg taaactcact tttggagata gcagagactg caaataggac 550

 atttcaagaa aaaggcatcc tggtaggaga gagcagaagt tttaaacctc 600

 atttgacctt catgaagttg tcaaaatcac cgtggctccg taagaatgga 650

 gtgaaaaaaa tagatcctga tttatatgaa aagtttatca gtcacagatt 700

 tggagaagaa atattatatc gcatagatct ttgctccatg ctgaagaaaa 750

 aacaaagtaa tggttattat cactgtgaat cttccattgt gattggtgaa 800

 aagaacggag gggagcccga tgacgctgaa ctagtaaggc tcagtaagag 850

 gctggtggag aacgcggtgc tcaaggctgt ccagcagtat ctggaggaaa 900

 cacagaataa aaacaagccg ggggagggga gctctgtgaa aaccgaagca 950

 gctgatcaga atggcaatga caatgagaac aacaggaaat gagcccggaa 1000

 cgcaggcccc catgtctctg tgcaaagcct ccctgcttcc ctctgctgag 1050

 tctagggact gacttgcagc gtgctgttta agttaagttt ctctggtgca 1100

 atctgtgaag attgcctaat acttttcatg atcgatgtgt tcgcattgct 1150

 gaaacacaac agaagaaaaa tggagtgctg ggactggcag aggaaattaa 1200

 ttgatgaaag aagaatggcc caagtttcat tcgccctcag ccacgcacaa 1250

 gggaaaggga actttgggtt atgcctcctg gacgcaaatt aaaggccgag 1300

 aaagaggcct tgccatcaat ggaatactgc catttatatt gcttagcagg 1350

 gcatttgact actttatctg aggccagaac tctcacacac agctatcaag 1400

 tgctaagttt aaaataatca ctgttggaat tgtcatctgt acaattagtc 1450

 cataatgttt catgtttgtc ctaagtgtgc tgttgctatg cagtgtgatc 1500

 tttatttata gtaaattatg tttcatgtaa atgatatatt tttggtgaaa 1550

 tgcaaccttt tctataaaat gtgggcaaca ttttaaagtt tttttaaaat 1600

 cctattttga taagtcagta tgccatattt aatgaaatgt tattatataa 1650

 tttttttttc ttaggcaaga aacctattgg aattcgagac ttaattaatg 1700

 aagctttgca tcgagaaacg atgggtctga agtccaaagt gaaacagata 1750

 aaggaacttt tattaaagcc tgagactcag gccagaatta ggagggagct 1800

 ttttgaagga agacttatta acaacagtaa ttcagcaaat gacgttgatt 1850

 tcagcacaac tttgacataa gctctacatt gcgattgtga caacatagct 1900

 tatgaaatct tttcagctta ttaagtagct ctttggtaaa caccaaagaa 1950

 gtttctgata gtgtctgcac aacagcaaac caacatttgg tgaggaatta 2000

 gcaatttctt gccaaagaaa attgattctg cccaattatt ttttgagcta 2050

 cacttgtgtt ttagaatatc tgtttctgta atattgagag ttattttata 2100

 gaaatgattt cttaattagc tgttgtgaga tatttctcgg gtccttgcag 2150

 aaaaaaacat acagactgtg aacaaatcat tcacaaacag aataaaacag 2200

 agccaacaac agtattttaa gggtcacttg cctcctgttg acacaattgt 2250

 tgctaaatca aaagaagcgt tgtccaggtg tgtctacatc tagtgttact 2300

 tttaatgaga atttgaatgt ttattgaaca atagtacttg aatgaacatt 2350

 tataaatgta attattgcga tcactggtta agaatgtttt atatatcctt 2400

 ataatatttt tcactgatca aaatgttgtt ctgctttttc atttcttaag 2450

 gaatacatgt ttgggatttt tattttttac gtgtccgaag ataagctcca 2500

 ggtcttatcg tatcccttgc catctgaact tgtttgcact gcttctgttt 2550

 gaaagagcat cttgaaaaac ttccccggta tgatgattgt tggtaacaac 2600

 tttttctata gtcattgatg gagtagatca tgatggaggg gaaatcactg 2650

 gagatcaaat atgtaaaatc atttcaaata taaaatccag tttactcatg 2700

 gattttagct attttttcac tgggtaaatt atactacatt tatttacaaa 2750

 tgagtttatg cattttcatg gctcttaata aacatattgt tttcccttga 2800

 aaaaaaaaaa aaaaaaaaaa a 2821

<210> 1428
<211> 326
<212> PRT
<213> Homo sapien

<400> 1428
 Met Ser Glu Glu Phe Glu Ala Asn Thr Met Asp Ser Leu Val Asp
   1               5                  10                  15

 Met Pro Phe Ala Thr Val Asp Ile Gln Asp Asp Cys Gly Ile Thr
                  20                  25                  30

 Asp Glu Pro Gln Ile Asn Leu Lys Arg Ser Gln Glu Asn Glu Trp
                  35                  40                  45

 Val Lys Ser Asp Gln Val Lys Lys Arg Lys Lys Lys Arg Lys Asp
                  50                  55                  60

 Tyr Gln Pro Asn Tyr Phe Leu Ser Ile Pro Ile Thr Asn Lys Glu
                  65                  70                  75

 Ile Ile Lys Gly Ile Lys Ile Leu Gln Asn Ala Ile Ile Gln Gln
                  80                  85                  90

 Asp Glu Arg Leu Ala Lys Ala Met Val Ser Asp Gly Ser Phe His
                  95                 100                 105

 Ile Thr Leu Leu Val Met Gln Leu Leu Asn Glu Asp Glu Val Asn
                 110                 115                 120

 Ile Gly Ile Asp Ala Leu Leu Glu Leu Lys Pro Phe Ile Glu Glu
                 125                 130                 135

 Leu Leu Gln Gly Lys His Leu Thr Leu Pro Phe Gln Gly Ile Gly
                 140                 145                 150

 Thr Phe Gly Asn Gln Val Gly Phe Val Lys Leu Ala Glu Gly Asp
                 155                 160                 165

 His Val Asn Ser Leu Leu Glu Ile Ala Glu Thr Ala Asn Arg Thr
                 170                 175                 180

 Phe Gln Glu Lys Gly Ile Leu Val Gly Glu Ser Arg Ser Phe Lys
                 185                 190                 195

 Pro His Leu Thr Phe Met Lys Leu Ser Lys Ser Pro Trp Leu Arg
                 200                 205                 210

 Lys Asn Gly Val Lys Lys Ile Asp Pro Asp Leu Tyr Glu Lys Phe
                 215                 220                 225

 Ile Ser His Arg Phe Gly Glu Glu Ile Leu Tyr Arg Ile Asp Leu
                 230                 235                 240

 Cys Ser Met Leu Lys Lys Lys Gln Ser Asn Gly Tyr Tyr His Cys
                 245                 250                 255

 Glu Ser Ser Ile Val Ile Gly Glu Lys Asn Gly Gly Glu Pro Asp
                 260                 265                 270

 Asp Ala Glu Leu Val Arg Leu Ser Lys Arg Leu Val Glu Asn Ala
                 275                 280                 285

 Val Leu Lys Ala Val Gln Gln Tyr Leu Glu Glu Thr Gln Asn Lys
                 290                 295                 300

 Asn Lys Pro Gly Glu Gly Ser Ser Val Lys Thr Glu Ala Ala Asp
                 305                 310                 315

 Gln Asn Gly Asn Asp Asn Glu Asn Asn Arg Lys
                 320                 325

<210> 1429
<211> 1809
<212> DNA
<213> Homo sapien

<400> 1429
 gtcttcctcc ctccctccct tcctcttact ctcattcatt tcatacacac 50

 tggctcacac atctactctc tctctctatc tctctcagaa tgacaattct 100

 aggtacaact tttggcatgg ttttttcttt acttcaagtc gtttctggag 150

 aaagtggcta tgctcaaaat ggagacttgg aagatgcaga actggatgac 200

 tactcattct catgctatag ccagttggaa gtgaatggat cgcagcactc 250

 actgacctgt gcttttgagg acccagatgt caacatcacc aatctggaat 300

 ttgaaatatg tggggccctc gtggaggtaa agtgcctgaa tttcaggaaa 350

 ctacaagaga tatatttcat cgagacaaag aaattcttac tgattggaaa 400

 gagcaatata tgtgtgaagg ttggagaaaa gagtctaacc tgcaaaaaaa 450

 tagacctaac cactatagtt aaacctgagg ctccttttga cctgagtgtc 500

 gtctatcggg aaggagccaa tgactttgtg gtgacattta atacatcaca 550

 cttgcaaaag aagtatgtaa aagttttaat gcacgatgta gcttaccgcc 600

 aggaaaagga tgaaaacaaa tggacgcatg tgaatttatc cagcacaaag 650

 ctgacactcc tgcagagaaa gctccaaccg gcagcaatgt atgagattaa 700

 agttcgatcc atccctgatc actattttaa aggcttctgg agtgaatgga 750

 gtccaagtta ttacttcaga actccagaga tcaataatag ctcaggggag 800

 atggatccta tcttactaac catcagcatt ttgagttttt tctctgtcgc 850

 tctgttggtc atcttggcct gtgtgttatg gaaaaaaagg attaagccta 900

 tcgtatggcc cagtctcccc gatcataaga agactctgga acatctttgt 950

 aagaaaccaa gaaaaaattt aaatgtgagt ttcaatcctg aaagtttcct 1000

 ggactgccag attcataggg tggatgacat tcaagctaga gatgaagtgg 1050

 aaggttttct gcaagatacg tttcctcagc aactagaaga atctgagaag 1100

 cagaggcttg gaggggatgt gcagagcccc aactgcccat ctgaggatgt 1150

 agtcatcact ccagaaagct ttggaagaga ttcatccctc acatgcctgg 1200

 ctgggaatgt cagtgcatgt gacgccccta ttctctcctc ttccaggtcc 1250

 ctagactgca gggagagtgg caagaatggg cctcatgtgt accaggacct 1300

 cctgcttagc cttgggacta caaacagcac gctgccccct ccattttctc 1350

 tccaatctgg aatcctgaca ttgaacccag ttgctcaggg tcagcccatt 1400

 cttacttccc tgggatcaaa tcaagaagaa gcatatgtca ccatgtccag 1450

 cttctaccaa aaccagtgaa gtgtaagaaa cccagactga acttaccgtg 1500

 agcgacaaag atgatttaaa agggaagtct agagttccta gtctccctca 1550

 cagcacagag aagacaaaat tagcaaaacc ccactacaca gtctgcaaga 1600

 ttctgaaaca ttgctttgac cactcttcct gagttcagtg gcactcaaca 1650

 tgagtcaaga gcatcctgct tctaccatgt ggatttggtc acaaggttta 1700

 aggtgaccca atgattcagc tatttaaaaa aaaaagagga aagaatgaaa 1750

 gagtaaagga aatgattgag gagtgaggaa ggcaggaaga gagcatgaga 1800

 ggaaaaaaa 1809

<210> 1430
<211> 459
<212> PRT
<213> Homo sapien

<400> 1430
 Met Thr Ile Leu Gly Thr Thr Phe Gly Met Val Phe Ser Leu Leu
   1               5                  10                  15

 Gln Val Val Ser Gly Glu Ser Gly Tyr Ala Gln Asn Gly Asp Leu
                  20                  25                  30

 Glu Asp Ala Glu Leu Asp Asp Tyr Ser Phe Ser Cys Tyr Ser Gln
                  35                  40                  45

 Leu Glu Val Asn Gly Ser Gln His Ser Leu Thr Cys Ala Phe Glu
                  50                  55                  60

 Asp Pro Asp Val Asn Ile Thr Asn Leu Glu Phe Glu Ile Cys Gly
                  65                  70                  75

 Ala Leu Val Glu Val Lys Cys Leu Asn Phe Arg Lys Leu Gln Glu
                  80                  85                  90

 Ile Tyr Phe Ile Glu Thr Lys Lys Phe Leu Leu Ile Gly Lys Ser
                  95                 100                 105

 Asn Ile Cys Val Lys Val Gly Glu Lys Ser Leu Thr Cys Lys Lys
                 110                 115                 120

 Ile Asp Leu Thr Thr Ile Val Lys Pro Glu Ala Pro Phe Asp Leu
                 125                 130                 135

 Ser Val Val Tyr Arg Glu Gly Ala Asn Asp Phe Val Val Thr Phe
                 140                 145                 150

 Asn Thr Ser His Leu Gln Lys Lys Tyr Val Lys Val Leu Met His
                 155                 160                 165

 Asp Val Ala Tyr Arg Gln Glu Lys Asp Glu Asn Lys Trp Thr His
                 170                 175                 180

 Val Asn Leu Ser Ser Thr Lys Leu Thr Leu Leu Gln Arg Lys Leu
                 185                 190                 195

 Gln Pro Ala Ala Met Tyr Glu Ile Lys Val Arg Ser Ile Pro Asp
                 200                 205                 210

 His Tyr Phe Lys Gly Phe Trp Ser Glu Trp Ser Pro Ser Tyr Tyr
                 215                 220                 225

 Phe Arg Thr Pro Glu Ile Asn Asn Ser Ser Gly Glu Met Asp Pro
                 230                 235                 240

 Ile Leu Leu Thr Ile Ser Ile Leu Ser Phe Phe Ser Val Ala Leu
                 245                 250                 255

 Leu Val Ile Leu Ala Cys Val Leu Trp Lys Lys Arg Ile Lys Pro
                 260                 265                 270

 Ile Val Trp Pro Ser Leu Pro Asp His Lys Lys Thr Leu Glu His
                 275                 280                 285

 Leu Cys Lys Lys Pro Arg Lys Asn Leu Asn Val Ser Phe Asn Pro
                 290                 295                 300

 Glu Ser Phe Leu Asp Cys Gln Ile His Arg Val Asp Asp Ile Gln
                 305                 310                 315

 Ala Arg Asp Glu Val Glu Gly Phe Leu Gln Asp Thr Phe Pro Gln
                 320                 325                 330

 Gln Leu Glu Glu Ser Glu Lys Gln Arg Leu Gly Gly Asp Val Gln
                 335                 340                 345

 Ser Pro Asn Cys Pro Ser Glu Asp Val Val Ile Thr Pro Glu Ser
                 350                 355                 360

 Phe Gly Arg Asp Ser Ser Leu Thr Cys Leu Ala Gly Asn Val Ser
                 365                 370                 375

 Ala Cys Asp Ala Pro Ile Leu Ser Ser Ser Arg Ser Leu Asp Cys
                 380                 385                 390

 Arg Glu Ser Gly Lys Asn Gly Pro His Val Tyr Gln Asp Leu Leu
                 395                 400                 405

 Leu Ser Leu Gly Thr Thr Asn Ser Thr Leu Pro Pro Pro Phe Ser
                 410                 415                 420

 Leu Gln Ser Gly Ile Leu Thr Leu Asn Pro Val Ala Gln Gly Gln
                 425                 430                 435

 Pro Ile Leu Thr Ser Leu Gly Ser Asn Gln Glu Glu Ala Tyr Val
                 440                 445                 450

 Thr Met Ser Ser Phe Tyr Gln Asn Gln
                 455

<210> 1431
<211> 4670
<212> DNA
<213> Homo sapien

<400> 1431
 ttgagctcaa agcttagcag cttcaatgtt gttgttaggc ataaacagct 50

 tgcaaatttc aatttttttt ctctcctcac ttttgaacta gatttgggca 100

 atggaggtga tgacagcatt ttagaagaca gaacaggaat tctaggtgtt 150

 taggcacgtt gaagagaaac ttgctagagg tgatgaagtg gaaagaaaaa 200

 gacaattcac tatagggatc aacattattg cagttctgca aaggatattt 250

 tcttttaaaa catccatatc tcttctttgc catggaaact acacccaatc 300

 tacctgaacc tgcggcaccc ctctgatgac ccatttggat tctctgattt 350

 cactgccaag attctcagtt ctccaaaata cttatcattc aggttgaata 400

 aaccagttct acagactgct tcttccatgc atttcccaat gatgctaact 450

 gcccttaaaa ttctttcaga tttggaactg tatctgtatg gaaacaacag 500

 agttttcttg aagtacaact aaggacaggt caccactagg cactaacatc 550

 gctgacttgc atgattatgg agatggtcta tctgatgctg aaaatgtctc 600

 tagttttttg acaacggcta aataaccatg ggatcaagtg gccttgggaa 650

 agcagcaaca ttagatgaac tgctgtgcac ttgcattgag atgtttgatg 700

 acaatggaga gctggataat agttatttgc caagaatagt tctactgatg 750

 caccgatggt atttatcttc cactgaattg gcagaaaaac ttctctgcat 800

 gtatcgaaat gccactggag aaagctgcaa tgaatttcga ttaaagatct 850

 gctacttcat gaggtactgg attctgaagt ttcctgcaga gtttaatttg 900

 gatcttggtt tgattcgtat gactgaggaa tttcgggaag tagctagtca 950

 actaggatat gaaaaacacg tcagcctcat cgacatatcc agcattcctt 1000

 cctatgactg gatgagaaga gtcacacaga ggaaaaaagt atccaagaag 1050

 ggaaaagcct gtctgctgtt tgaccatctg gagcccattg aattggctga 1100

 gcacctcact tttctggagc ataaatcttt tagaaggatc tcattcactg 1150

 attaccaaag ctatgtcatc catggctgcc tggagaataa tccaaccttg 1200

 gaaagatcga ttgctttatt taatggaatc tctaagtggg tccagttgat 1250

 ggttcttagc aaaccaaccc cccagcaaag ggcagaagtc atcacaaagt 1300

 ttatcaatgt tgcaaagaag ctccttcagc tcaaaaattt taacaccctg 1350

 atggcagtgg tgggaggcct cagtcatagt tccatttcac gcctcaaaga 1400

 gacccattct catctttctt cagaagttac aaagaactgg aatgaaatga 1450

 cagagttggt ctcctccaac ggcaattact gcaattaccg caaggccttt 1500

 gccgactgcg atggcttcaa aatccccatc cttggagtac acttgaaaga 1550

 cttgatagct gtccatgtca ttttcccaga ctggacagag gagaacaaag 1600

 tgaacattgt gaaaatgcac cagctctccg ttaccctgag tgaactagtc 1650

 tccctgcaga atgcctctca ccacttagaa cccaacatgg atttgatcaa 1700

 cctgctcacg ctttccctgg acctctatca cactgaagat gatatttaca 1750

 aactgtcact ggtgctggag cctagaaatt ctaaatcgca gcctacctcc 1800

 cctacgacgc ccaacaagcc tgtggtaccc ctggagtggg cattaggggt 1850

 gatgccaaag ccagacccca cggtcatcaa caagcacata aggaaattag 1900

 tggagtctgt atttagaaac tatgatcacg accatgatgg gtacatttcc 1950

 caagaggact ttgaaagtat agctgccaat tttcccttct tggattcctt 2000

 ctgtgttctg gacaaagatc aggatggcct aattagtaaa gatgaaatga 2050

 tggcttactt cctgagagct aaatcccaac tacactgtaa aatgggacca 2100

 ggatttatcc ataattttca ggagatgacc tatctcaagc caaccttctg 2150

 cgaacactgt gcgggatttc tctggggcat aatcaagcaa ggatacaaat 2200

 gcaaagactg tggagccaat tgtcacaaac agtgcaaaga cctcctggtt 2250

 ctggcctgca ggagatttgc ccgggcgccc tccttgagca gtggtcatgg 2300

 gtcactgcct ggaagcccct cgctgccccc agcgcaggat gaggtgtttg 2350

 agttccctgg agtcactgct ggacacaggg atttagacag cagagccatc 2400

 acactggtta caggctcttc tcgcaagatc tctgtgaggc tacagagggc 2450

 caccaccagc caggccaccc agactgaacc tgtctggtca gaggctggct 2500

 ggggggactc ggggtcccac accttcccta aaatgaaatc caagttccat 2550

 gacaaagcag caaaggacaa aggctttgcc aaatgggaaa atgagaagcc 2600

 cagggtgcat gctggtgtgg atgttgtaga ccggggcacg gagtttgaac 2650

 ttgaccagga tgaaggagaa gagaccagac aggatggtga ggatggctga 2700

 cttcaggctg cggaaactga aggcaataat gttggctttt ggaaggggca 2750

 agacgagaaa ctctgaagaa agctctgact ctcaggaagt tatctggaaa 2800

 gatacctgga tgtttactgc cttgggacac tgtgggatct ccatgtttgg 2850

 actatgggac agagaattga ccctaactaa ctatgaacta tttatttcct 2900

 cctcccctac ccctagttaa gtgccacaaa gactgtgtta tgtagtcagt 2950

 acttttttct catgtatctt tctctagacc atttatatac gggtgaaatg 3000

 aaagcctttt tgcatgtact tgatactcag tctgtaaact cagacttcgc 3050

 tttttttgtg agactatcct ttcaatattt ttataaactt ttgtgtgtgc 3100

 tgtggcaggg aacagttaac aaggagttta tttagagggg tttttttcat 3150

 tttttgtttt tcttgttttg ttttgttttg ttttgttctt cttggtgtgc 3200

 tttttggatg ggaccagaac ttaacatttt cctgaggact aggaagctca 3250

 tcagacactg gaatgcagtg attcttctaa tgatggtcaa ctgcaaggag 3300

 aaactgttta catccttccc actacacagt tgctatgata tgtaacaagt 3350

 cacacatgta tatatcacac aagtcttacc aattctgcgt cactaggaag 3400

 ctatagcatg gtcgtgaaag ctctcctaat acttacttaa atagccatgg 3450

 aagaaaatta tgcttgtccc ttctgactgg gttaagccat ctttcttaag 3500

 attcctgaag tagaaatagc aattaagaaa ttaattcaag ttttgacggt 3550

 taacatttag cagaaaaaca aaccattgaa taagctacta ggtgaaatgc 3600

 aaaacaacca tcaatttttt taaactcaat aattttgtga aaaaaaaaac 3650

 caccaccaaa cttttggttg taaaagagaa cccttgttcc cttcctaaga 3700

 aactgccttc cacaattaaa gaatactcat agaaagaaaa taatcataaa 3750

 tcatatttga ttaacatttc atttaagctt ttaaaatatc aattttttaa 3800

 atagctccca tttacccaaa ataactagtt atgggtctat ttcttccatg 3850

 attagaggag agagaacttg attcaagata ctgaaaaata gagctgggac 3900

 tgagcctgtg aatgacagga atgatctatt accaggtgac tagtcggaaa 3950

 ctacacagac gtgcactggt ctgcatttgg gggctaaagt gtatatattc 4000

 catttaaaat ggaatttgtt tgtatttggg gcagtcttca gtaaagcctt 4050

 tctcctttct tttctccatt gaggacagtt ctgctcagca aaattgttga 4100

 gtacctgttc tgggcaggtc ccacgctata tgcacaaagt taagaaaaac 4150

 ttggtcttag cccttgggag ctgacagccc atgggcatta aggcaaagta 4200

 gttccagtga tttaaaatac ggttccaaat acgctaaaac caacttgtgc 4250

 caaccagatt tacagattgg aaatactgca gatgatgtga agttatcagt 4300

 tggaggagct gtgattaagc tggataataa gagaacgtgc catctgtaaa 4350

 gcactcagaa ggcagccatc cctagatgtt ggtttcatgt atattacact 4400

 atctactact atccataaat gcaataatat gcatgttaac aacattaaaa 4450

 acagcaaaca gcaatctaag tacagaaaag ctttttgtgt gtttaaaaaa 4500

 attgaagaaa attcaggaag aaacgtgtta ataaacattg tactgttctt 4550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4600

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4650

 aaaaaaaaaa aaaaaaaaaa 4670

<210> 1432
<211> 690
<212> PRT
<213> Homo sapien

<400> 1432
 Met Gly Ser Ser Gly Leu Gly Lys Ala Ala Thr Leu Asp Glu Leu
   1               5                  10                  15

 Leu Cys Thr Cys Ile Glu Met Phe Asp Asp Asn Gly Glu Leu Asp
                  20                  25                  30

 Asn Ser Tyr Leu Pro Arg Ile Val Leu Leu Met His Arg Trp Tyr
                  35                  40                  45

 Leu Ser Ser Thr Glu Leu Ala Glu Lys Leu Leu Cys Met Tyr Arg
                  50                  55                  60

 Asn Ala Thr Gly Glu Ser Cys Asn Glu Phe Arg Leu Lys Ile Cys
                  65                  70                  75

 Tyr Phe Met Arg Tyr Trp Ile Leu Lys Phe Pro Ala Glu Phe Asn
                  80                  85                  90

 Leu Asp Leu Gly Leu Ile Arg Met Thr Glu Glu Phe Arg Glu Val
                  95                 100                 105

 Ala Ser Gln Leu Gly Tyr Glu Lys His Val Ser Leu Ile Asp Ile
                 110                 115                 120

 Ser Ser Ile Pro Ser Tyr Asp Trp Met Arg Arg Val Thr Gln Arg
                 125                 130                 135

 Lys Lys Val Ser Lys Lys Gly Lys Ala Cys Leu Leu Phe Asp His
                 140                 145                 150

 Leu Glu Pro Ile Glu Leu Ala Glu His Leu Thr Phe Leu Glu His
                 155                 160                 165

 Lys Ser Phe Arg Arg Ile Ser Phe Thr Asp Tyr Gln Ser Tyr Val
                 170                 175                 180

 Ile His Gly Cys Leu Glu Asn Asn Pro Thr Leu Glu Arg Ser Ile
                 185                 190                 195

 Ala Leu Phe Asn Gly Ile Ser Lys Trp Val Gln Leu Met Val Leu
                 200                 205                 210

 Ser Lys Pro Thr Pro Gln Gln Arg Ala Glu Val Ile Thr Lys Phe
                 215                 220                 225

 Ile Asn Val Ala Lys Lys Leu Leu Gln Leu Lys Asn Phe Asn Thr
                 230                 235                 240

 Leu Met Ala Val Val Gly Gly Leu Ser His Ser Ser Ile Ser Arg
                 245                 250                 255

 Leu Lys Glu Thr His Ser His Leu Ser Ser Glu Val Thr Lys Asn
                 260                 265                 270

 Trp Asn Glu Met Thr Glu Leu Val Ser Ser Asn Gly Asn Tyr Cys
                 275                 280                 285

 Asn Tyr Arg Lys Ala Phe Ala Asp Cys Asp Gly Phe Lys Ile Pro
                 290                 295                 300

 Ile Leu Gly Val His Leu Lys Asp Leu Ile Ala Val His Val Ile
                 305                 310                 315

 Phe Pro Asp Trp Thr Glu Glu Asn Lys Val Asn Ile Val Lys Met
                 320                 325                 330

 His Gln Leu Ser Val Thr Leu Ser Glu Leu Val Ser Leu Gln Asn
                 335                 340                 345

 Ala Ser His His Leu Glu Pro Asn Met Asp Leu Ile Asn Leu Leu
                 350                 355                 360

 Thr Leu Ser Leu Asp Leu Tyr His Thr Glu Asp Asp Ile Tyr Lys
                 365                 370                 375

 Leu Ser Leu Val Leu Glu Pro Arg Asn Ser Lys Ser Gln Pro Thr
                 380                 385                 390

 Ser Pro Thr Thr Pro Asn Lys Pro Val Val Pro Leu Glu Trp Ala
                 395                 400                 405

 Leu Gly Val Met Pro Lys Pro Asp Pro Thr Val Ile Asn Lys His
                 410                 415                 420

 Ile Arg Lys Leu Val Glu Ser Val Phe Arg Asn Tyr Asp His Asp
                 425                 430                 435

 His Asp Gly Tyr Ile Ser Gln Glu Asp Phe Glu Ser Ile Ala Ala
                 440                 445                 450

 Asn Phe Pro Phe Leu Asp Ser Phe Cys Val Leu Asp Lys Asp Gln
                 455                 460                 465

 Asp Gly Leu Ile Ser Lys Asp Glu Met Met Ala Tyr Phe Leu Arg
                 470                 475                 480

 Ala Lys Ser Gln Leu His Cys Lys Met Gly Pro Gly Phe Ile His
                 485                 490                 495

 Asn Phe Gln Glu Met Thr Tyr Leu Lys Pro Thr Phe Cys Glu His
                 500                 505                 510

 Cys Ala Gly Phe Leu Trp Gly Ile Ile Lys Gln Gly Tyr Lys Cys
                 515                 520                 525

 Lys Asp Cys Gly Ala Asn Cys His Lys Gln Cys Lys Asp Leu Leu
                 530                 535                 540

 Val Leu Ala Cys Arg Arg Phe Ala Arg Ala Pro Ser Leu Ser Ser
                 545                 550                 555

 Gly His Gly Ser Leu Pro Gly Ser Pro Ser Leu Pro Pro Ala Gln
                 560                 565                 570

 Asp Glu Val Phe Glu Phe Pro Gly Val Thr Ala Gly His Arg Asp
                 575                 580                 585

 Leu Asp Ser Arg Ala Ile Thr Leu Val Thr Gly Ser Ser Arg Lys
                 590                 595                 600

 Ile Ser Val Arg Leu Gln Arg Ala Thr Thr Ser Gln Ala Thr Gln
                 605                 610                 615

 Thr Glu Pro Val Trp Ser Glu Ala Gly Trp Gly Asp Ser Gly Ser
                 620                 625                 630

 His Thr Phe Pro Lys Met Lys Ser Lys Phe His Asp Lys Ala Ala
                 635                 640                 645

 Lys Asp Lys Gly Phe Ala Lys Trp Glu Asn Glu Lys Pro Arg Val
                 650                 655                 660

 His Ala Gly Val Asp Val Val Asp Arg Gly Thr Glu Phe Glu Leu
                 665                 670                 675

 Asp Gln Asp Glu Gly Glu Glu Thr Arg Gln Asp Gly Glu Asp Gly
                 680                 685                 690

<210> 1433
<211> 2058
<212> DNA
<213> Homo sapien

<400> 1433
 gcccagacct atggattgaa agcgtgtgct ttacccatct gctgtcttgc 50

 tccatctgag accagagcca agatctgccc aggactggaa tgctttcccg 100

 agtggcttga gttggagcct gggactagga gcagccttat tgaggtacaa 150

 ttcatgtgct tgtgggtttg gatggcacaa tctgtgtctg ggctaaggaa 200

 agcagacttg gcaccaacat taaccctgac agatccaggc atctattcca 250

 ggaactggaa gccaagcgca acaggtgctt ggaggtcatc atgatcagcc 300

 cagaccccag gccctcccct ggcttggccc ggtgggctga gagctatgag 350

 gccaagtgtg agcgcaggca agagatccgt gaaagccgcc gctgccgtcc 400

 caatgtgacc acttgccgcc aggtggggaa gacgctgagg atccaacaga 450

 gagagcagct ccagagagct cgactgcagc agttcttcag gaggaggaac 500

 ctggagctag aggagaaggg caaagcgcag catccccagg ccagggagca 550

 agggccctcc aggcggccag gacaggtgac aggcaccagc tctgaagtct 600

 ttccagccca gcatcctcct ccctcaggca tctgcaggga tctgtctgac 650

 cacctctcct cacaggctgg gggccttcct ccacaggaca ctcccatcaa 700

 gaagccaccc aaacaccacc gtggtactca gacaaaggca gaaggaccaa 750

 caattaagaa cgatgccagt cagcaaacca attacggagt tgcagttctg 800

 gataaggaaa tcatccagct ttctgattac ctcaaagagg ccctacaaag 850

 ggagctggtc ctaaaacaga aaatggtgat tctccaagac ctactgtcca 900

 ctctgattca ggcctctgac agctcttgga agggacagct taatgaagac 950

 aaactgaagg ggaaactgag atccttagaa aaccagctat acacctgtac 1000

 ccagaaatac tccccttggg gaatgaaaaa agtactactg gagatggaag 1050

 accagaaaaa cagctatgag cagaaggcca aggagtcact gcagaaagtg 1100

 ctggaggaga aaatgaatgc agagcagcaa ctacagagca cacagcgatc 1150

 cctggccctg gcagagcaga agtgtgaaga gtggaggagc cagtatgagg 1200

 ctctgaagga ggactggagg acccttggga cccagcacag ggagctggag 1250

 agccaactcc acgtgcttca gtccaaactg cagggagcag atagcaggga 1300

 cttacagatg aaccaggccc tgcgattttt ggaaaatgag caccagcaac 1350

 tgcaggccaa gattgaatgc ctgcaagggg acagagacct gtgcagcttg 1400

 gatacccagg acctacaaga tcaactaaaa aggtcagagg cagagaaact 1450

 caccctggtg accagagtac agcagttgca gggtttgctt caaaatcaat 1500

 ccttacagct tcaagaacag gagaaactct taacaaagaa agatcaggct 1550

 ttgcccgtgt ggagtccaaa gtccttccct aacgaagtgg agcctgaggg 1600

 tacagggaag gagaaagact gggatctcag agaccagctg caaaagaaga 1650

 ctttgcagct ccaggccaag gaaaaggagt gcagagaact gcattcagaa 1700

 ttagacaacc tcagtgacga gtatctctcc tgcctgcgta agctgcagca 1750

 ctgtcgagaa gagctgaacc agagccagca gctgcctccc agaaggcaat 1800

 gtgggcgatg gctcccagtg ctgatggtgg tgattgctgc agcactggca 1850

 gtgttcctgg ccaataaaga caacctgatg atctgaataa tttgtgacaa 1900

 ctgccttggg tgaaaatcag aagcaagcaa ctcagcgaaa aactcagaag 1950

 gtttgggtac attacagctt gggttttcca actgacttag gatttctgac 2000

 tttttattaa tttcttaacc tactgtaaat aaacttcacc tgaccagatt 2050

 gttcctca 2058

<210> 1434
<211> 531
<212> PRT
<213> Homo sapien

<400> 1434
 Met Ile Ser Pro Asp Pro Arg Pro Ser Pro Gly Leu Ala Arg Trp
   1               5                  10                  15

 Ala Glu Ser Tyr Glu Ala Lys Cys Glu Arg Arg Gln Glu Ile Arg
                  20                  25                  30

 Glu Ser Arg Arg Cys Arg Pro Asn Val Thr Thr Cys Arg Gln Val
                  35                  40                  45

 Gly Lys Thr Leu Arg Ile Gln Gln Arg Glu Gln Leu Gln Arg Ala
                  50                  55                  60

 Arg Leu Gln Gln Phe Phe Arg Arg Arg Asn Leu Glu Leu Glu Glu
                  65                  70                  75

 Lys Gly Lys Ala Gln His Pro Gln Ala Arg Glu Gln Gly Pro Ser
                  80                  85                  90

 Arg Arg Pro Gly Gln Val Thr Gly Thr Ser Ser Glu Val Phe Pro
                  95                 100                 105

 Ala Gln His Pro Pro Pro Ser Gly Ile Cys Arg Asp Leu Ser Asp
                 110                 115                 120

 His Leu Ser Ser Gln Ala Gly Gly Leu Pro Pro Gln Asp Thr Pro
                 125                 130                 135

 Ile Lys Lys Pro Pro Lys His His Arg Gly Thr Gln Thr Lys Ala
                 140                 145                 150

 Glu Gly Pro Thr Ile Lys Asn Asp Ala Ser Gln Gln Thr Asn Tyr
                 155                 160                 165

 Gly Val Ala Val Leu Asp Lys Glu Ile Ile Gln Leu Ser Asp Tyr
                 170                 175                 180

 Leu Lys Glu Ala Leu Gln Arg Glu Leu Val Leu Lys Gln Lys Met
                 185                 190                 195

 Val Ile Leu Gln Asp Leu Leu Ser Thr Leu Ile Gln Ala Ser Asp
                 200                 205                 210

 Ser Ser Trp Lys Gly Gln Leu Asn Glu Asp Lys Leu Lys Gly Lys
                 215                 220                 225

 Leu Arg Ser Leu Glu Asn Gln Leu Tyr Thr Cys Thr Gln Lys Tyr
                 230                 235                 240

 Ser Pro Trp Gly Met Lys Lys Val Leu Leu Glu Met Glu Asp Gln
                 245                 250                 255

 Lys Asn Ser Tyr Glu Gln Lys Ala Lys Glu Ser Leu Gln Lys Val
                 260                 265                 270

 Leu Glu Glu Lys Met Asn Ala Glu Gln Gln Leu Gln Ser Thr Gln
                 275                 280                 285

 Arg Ser Leu Ala Leu Ala Glu Gln Lys Cys Glu Glu Trp Arg Ser
                 290                 295                 300

 Gln Tyr Glu Ala Leu Lys Glu Asp Trp Arg Thr Leu Gly Thr Gln
                 305                 310                 315

 His Arg Glu Leu Glu Ser Gln Leu His Val Leu Gln Ser Lys Leu
                 320                 325                 330

 Gln Gly Ala Asp Ser Arg Asp Leu Gln Met Asn Gln Ala Leu Arg
                 335                 340                 345

 Phe Leu Glu Asn Glu His Gln Gln Leu Gln Ala Lys Ile Glu Cys
                 350                 355                 360

 Leu Gln Gly Asp Arg Asp Leu Cys Ser Leu Asp Thr Gln Asp Leu
                 365                 370                 375

 Gln Asp Gln Leu Lys Arg Ser Glu Ala Glu Lys Leu Thr Leu Val
                 380                 385                 390

 Thr Arg Val Gln Gln Leu Gln Gly Leu Leu Gln Asn Gln Ser Leu
                 395                 400                 405

 Gln Leu Gln Glu Gln Glu Lys Leu Leu Thr Lys Lys Asp Gln Ala
                 410                 415                 420

 Leu Pro Val Trp Ser Pro Lys Ser Phe Pro Asn Glu Val Glu Pro
                 425                 430                 435

 Glu Gly Thr Gly Lys Glu Lys Asp Trp Asp Leu Arg Asp Gln Leu
                 440                 445                 450

 Gln Lys Lys Thr Leu Gln Leu Gln Ala Lys Glu Lys Glu Cys Arg
                 455                 460                 465

 Glu Leu His Ser Glu Leu Asp Asn Leu Ser Asp Glu Tyr Leu Ser
                 470                 475                 480

 Cys Leu Arg Lys Leu Gln His Cys Arg Glu Glu Leu Asn Gln Ser
                 485                 490                 495

 Gln Gln Leu Pro Pro Arg Arg Gln Cys Gly Arg Trp Leu Pro Val
                 500                 505                 510

 Leu Met Val Val Ile Ala Ala Ala Leu Ala Val Phe Leu Ala Asn
                 515                 520                 525

 Lys Asp Asn Leu Met Ile
                 530

<210> 1435
<211> 3125
<212> DNA
<213> Homo sapien

<400> 1435
 gcccagttgg agccagacag cggggtggac aagtggcgtg tgtgctgcga 50

 ccccgaggga agatgaacgg gacgcggaac tggtgtaccc tggtggacgt 100

 gcacccagag gaccaggcgg cgggcagcgt ggacattctc aggctgactc 150

 tccagggtga actgacagga gatgaacttg aacacatagc ccagaaggcg 200

 ggcaggaaga cctatgccat ggtgtccagc cactcagctg gtcattctct 250

 ggcttcagaa ctggtggagt cccatgatgg acatgaggag atcattaagg 300

 tgtacttgaa ggggaggtct ggagacaaga tgattcacga gaagaatatt 350

 aaccagctga agagtgaggt ccagtacatc caggaggcca ggaactgcct 400

 acagaagctc cgggaggata taagtagcaa gcttgacagg aacctaggag 450

 attctctcca tcgacaggag atacaggtgg tgctagaaaa gccaaatggc 500

 tttagtcaga gtcccacagc cctgtacagc agcccacctg aggtggacac 550

 ctgtataaat gaggatgttg agagcttgag gaagacggtg caggacttgc 600

 tggccaagct tcaggaggcc aagcggcaac accagtcaga ctgtgtggct 650

 tttgaggtca cactcagccg gtaccagagg gaagcagaac aaagtaatgt 700

 ggcccttcag agagaggagg acagagtgga gcagaaagag gcagaagtcg 750

 gagagctgca gaggcgcttg ctagggatgg agacggagca tcaggcctta 800

 ctggcgaaag tgagggaagg ggaggtggcc ctagaggaac ttcggagcaa 850

 caatgctgac tgccaagcag aacgagaaaa ggctgctacc ctggaaaagg 900

 aagtggccgg gttgcgggag aagatccacc acttggatga catgctcaag 950

 agccagcagc ggaaagtccg gcaaatgata gagcagctcc agaattcaaa 1000

 agctgtgatc cagtcaaagg acgccaccat ccaggagctc aaggagaaaa 1050

 tcgcctatct ggaggcagag aatttagaga tgcatgaccg gatggaacac 1100

 ctgatagaaa aacaaatcag tcatggcaac ttcagcaccc aggcccgggc 1150

 caagacagag aacccgggca gtattaggat atccaagccg cctagcccga 1200

 agcccatgcc tgtcatccga gtggtggaaa cctgagctgc ctggagatgg 1250

 ttgctgccat tgctgctgcc tctgcctcgg agaagcccac tgcccctgtt 1300

 ggctgttaac actgcctttg acttcctgac tgtcccctgg ctgcacccag 1350

 gacttcgggc tcctgtgtct caccattccc aagcccctgg ccactctaag 1400

 ctgggcagac ggagcacgag cacctattca aggcactgca gccctttgga 1450

 agacattgtc ctgcaagcag gagccagggc aatatctata ttcctacagt 1500

 gactattttt ctctgtagag agcctccctt ctgttgtaga ctggactctg 1550

 gctgcgccat aagccaggcc ttcatcagat tgggagaggt gacaagattt 1600

 gcctcagccc taaaagctgg agacacagat gtccagagtg attggagaat 1650

 gtcctggggg aatgaagttc cttccacaaa cacagctcag ttcttagcaa 1700

 caaactgttt gtttttctac ttgctccatc tgcagcctac gctgccctgg 1750

 cctcctgcag acagatagtg gggttacctg gcaaggcctg gtgagagcca 1800

 gtgaacctaa gctttgactg ggtggccttg tctttctggg gaggagggaa 1850

 tgtacattca gggagtagcc ttttgcggaa aaattctcta gggctacaga 1900

 cagtcatgtg tgacttctct ctgctgtgaa aactcccaga gtctctttag 1950

 ggattttccc taaggtgtac caccaggcac acctcagtct tcttgaccca 2000

 gagcctgaaa actgttttca ctgggttcca ccagtcccag caaaatcctc 2050

 tttgtattta ttttgctaag ttattggtgg ttttgcttac atctcatgat 2100

 tgatataata ccaaagttct atagccttct cttgcagtat ttggatttgc 2150

 ttgaaaccgg gaaaactgtt cccattaggc ttgttaatgt cagagtgaca 2200

 ctattatgaa tctttctctc cctttcctct gcctgtttct tctctctttc 2250

 tccttcaaac ttgctctgca gctaaggaag gtgagtctac tttccctgag 2300

 gctttggggt cagagtatat gttgtttgga gaaagagggc aatcaggact 2350

 cttctgggac ccagatgagt tcttcactag cccttctgaa ccccttgctc 2400

 cataattggt cttttatcct ggctctgaat gaccctgcag gtcatcatgg 2450

 ttttcttttt ttattgtttt tttttttctg agacagagtc tcactctgtc 2500

 acccaggctg gagtgcagta gcgcgatctc agctcactgc aacctctgcc 2550

 tcccggattt aagcgattct tctgcctcag cctcccgagt agctgggact 2600

 acaggtgtgc caccacgcct ggctgatttt tgtattttta gtagagatgg 2650

 ggtttcacca tactggctag gctggtctcg aattcctgac ctcaggtgat 2700

 ccacccacct cggcttccca aagtgctagg attataggct tgagctactg 2750

 tgcccggccc atggtgtttt tctttagggc tcttcctaca gccttgagaa 2800

 gtagataggc atcagagtat ggtactatag gaatcagaaa aattcaaaac 2850

 aaatgtggat taagtgttta ggctctatgt ggctcacgca gccagaatcc 2900

 ttaagtctgt gtgtttctgt gtctcaagac tgggctcaca ttctggcttt 2950

 gtccataaca atgctctggg atttcaggga gttccctcat ttgtaaaatg 3000

 agggggtcag agcaggtgat atccatgttt cttccctttc tgatattgtt 3050

 gtctgtggca tattctttgt atggcgaatt taataaatta tattaatgtg 3100

 tctctttgaa aaaaaaaaaa aaaaa 3125

<210> 1436
<211> 390
<212> PRT
<213> Homo sapien

<400> 1436
 Met Asn Gly Thr Arg Asn Trp Cys Thr Leu Val Asp Val His Pro
   1               5                  10                  15

 Glu Asp Gln Ala Ala Gly Ser Val Asp Ile Leu Arg Leu Thr Leu
                  20                  25                  30

 Gln Gly Glu Leu Thr Gly Asp Glu Leu Glu His Ile Ala Gln Lys
                  35                  40                  45

 Ala Gly Arg Lys Thr Tyr Ala Met Val Ser Ser His Ser Ala Gly
                  50                  55                  60

 His Ser Leu Ala Ser Glu Leu Val Glu Ser His Asp Gly His Glu
                  65                  70                  75

 Glu Ile Ile Lys Val Tyr Leu Lys Gly Arg Ser Gly Asp Lys Met
                  80                  85                  90

 Ile His Glu Lys Asn Ile Asn Gln Leu Lys Ser Glu Val Gln Tyr
                  95                 100                 105

 Ile Gln Glu Ala Arg Asn Cys Leu Gln Lys Leu Arg Glu Asp Ile
                 110                 115                 120

 Ser Ser Lys Leu Asp Arg Asn Leu Gly Asp Ser Leu His Arg Gln
                 125                 130                 135

 Glu Ile Gln Val Val Leu Glu Lys Pro Asn Gly Phe Ser Gln Ser
                 140                 145                 150

 Pro Thr Ala Leu Tyr Ser Ser Pro Pro Glu Val Asp Thr Cys Ile
                 155                 160                 165

 Asn Glu Asp Val Glu Ser Leu Arg Lys Thr Val Gln Asp Leu Leu
                 170                 175                 180

 Ala Lys Leu Gln Glu Ala Lys Arg Gln His Gln Ser Asp Cys Val
                 185                 190                 195

 Ala Phe Glu Val Thr Leu Ser Arg Tyr Gln Arg Glu Ala Glu Gln
                 200                 205                 210

 Ser Asn Val Ala Leu Gln Arg Glu Glu Asp Arg Val Glu Gln Lys
                 215                 220                 225

 Glu Ala Glu Val Gly Glu Leu Gln Arg Arg Leu Leu Gly Met Glu
                 230                 235                 240

 Thr Glu His Gln Ala Leu Leu Ala Lys Val Arg Glu Gly Glu Val
                 245                 250                 255

 Ala Leu Glu Glu Leu Arg Ser Asn Asn Ala Asp Cys Gln Ala Glu
                 260                 265                 270

 Arg Glu Lys Ala Ala Thr Leu Glu Lys Glu Val Ala Gly Leu Arg
                 275                 280                 285

 Glu Lys Ile His His Leu Asp Asp Met Leu Lys Ser Gln Gln Arg
                 290                 295                 300

 Lys Val Arg Gln Met Ile Glu Gln Leu Gln Asn Ser Lys Ala Val
                 305                 310                 315

 Ile Gln Ser Lys Asp Ala Thr Ile Gln Glu Leu Lys Glu Lys Ile
                 320                 325                 330

 Ala Tyr Leu Glu Ala Glu Asn Leu Glu Met His Asp Arg Met Glu
                 335                 340                 345

 His Leu Ile Glu Lys Gln Ile Ser His Gly Asn Phe Ser Thr Gln
                 350                 355                 360

 Ala Arg Ala Lys Thr Glu Asn Pro Gly Ser Ile Arg Ile Ser Lys
                 365                 370                 375

 Pro Pro Ser Pro Lys Pro Met Pro Val Ile Arg Val Val Glu Thr
                 380                 385                 390

<210> 1437
<211> 1770
<212> DNA
<213> Homo sapien

<400> 1437
 gaggagtgga ttacatattc caacagttgt tattacattg gtaaggaaag 50

 aagaacttgg gaagaaagag tttgctggcc tgtgcttcga agaactctga 100

 tctgctttct atagataatg aggaagaaat ggtatgtgtg gggacttccc 150

 agttggctgt aagttgccat ttgaactaaa cgaaatagat caggaactga 200

 ggacatatct aaattttcta gttttataga aggcttttat ccacaagaat 250

 caagatcttc cctctctgag caggaatcct ttgtgcattg aagactttag 300

 attcctctct gcggtagacg tgcacttata agtatttgat ggggtggatt 350

 cgtggtcgga ggtctcgaca cagctgggag atgagtgaat ttcataatta 400

 taacttggat ctgaagaaga gtgatttttc aacacgatgg caaaagcaaa 450

 gatgtccagt agtcaaaagc aaatgtagag aaaatgcatc tccatttttt 500

 ttctgctgct tcatcgctgt agccatggga atccgtttca ttattatggt 550

 agcaatatgg agtgctgtat tcctaaactc attattcaac caagaagttc 600

 aaattccctt gaccgaaagt tactgtggcc catgtcctaa aaactggata 650

 tgttacaaaa ataactgcta ccaatttttt gatgagagta aaaactggta 700

 tgagagccag gcttcttgta tgtctcaaaa tgccagcctt ctgaaagtat 750

 acagcaaaga ggaccaggat ttacttaaac tggtgaagtc atatcattgg 800

 atgggactag tacacattcc aacaaatgga tcttggcagt gggaagatgg 850

 ctccattctc tcacccaacc tactaacaat aattgaaatg cagaagggag 900

 actgtgcact ctatgcctcg agctttaaag gctatataga aaactgttca 950

 actccaaata catacatctg catgcaaagg actgtgtaaa gatgatcaac 1000

 catctcaata aaagccagga acagagaaga gattacacca gcggtaacac 1050

 tgccaaccga gactaaagga aacaaacaaa aacaggacaa aatgaccaaa 1100

 gactgtcaga tttcttagac tccacaggac caaaccatag aacaatttca 1150

 ctgcaaacat gcatgattct ccaagacaaa agaagagaga tcctaaaggc 1200

 aattcagata tccccaaggc tgcctctccc accacaagcc cagagtggat 1250

 gggctggggg aggggtgctg ttttaatttc taaaggtagg accaacaccc 1300

 aggggatcag tgaaggaaga gaaggccagc agatcagtga gagtgcaacc 1350

 ccaccctcca caggaaattg cctcatgggc agggccacag cagagagaca 1400

 cagcatgggc agtgccttcc ctgcctgtgg gggtcatgct gccactttta 1450

 atgggtcctc cacccaacgg ggtcagggag gtggtgctgc cccagtgggc 1500

 catgattatc ttaaaggcat tattctccag ccttaagatc ttaggacgtt 1550

 tcctttgcta tgatttgtac ttgcttgagt cccatgactg tttctcttcc 1600

 tctctttctt ccttttggaa tagtaatatc catcctatgt ttgtcccact 1650

 attgtatttt ggaagcacat aacttgtttg gtttcacagg ttcacagtta 1700

 agaaggaatt ttgcctctga ataaatagaa tcttgagtct catgcaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa 1770

<210> 1438
<211> 216
<212> PRT
<213> Homo sapien

<400> 1438
 Met Gly Trp Ile Arg Gly Arg Arg Ser Arg His Ser Trp Glu Met
   1               5                  10                  15

 Ser Glu Phe His Asn Tyr Asn Leu Asp Leu Lys Lys Ser Asp Phe
                  20                  25                  30

 Ser Thr Arg Trp Gln Lys Gln Arg Cys Pro Val Val Lys Ser Lys
                  35                  40                  45

 Cys Arg Glu Asn Ala Ser Pro Phe Phe Phe Cys Cys Phe Ile Ala
                  50                  55                  60

 Val Ala Met Gly Ile Arg Phe Ile Ile Met Val Ala Ile Trp Ser
                  65                  70                  75

 Ala Val Phe Leu Asn Ser Leu Phe Asn Gln Glu Val Gln Ile Pro
                  80                  85                  90

 Leu Thr Glu Ser Tyr Cys Gly Pro Cys Pro Lys Asn Trp Ile Cys
                  95                 100                 105

 Tyr Lys Asn Asn Cys Tyr Gln Phe Phe Asp Glu Ser Lys Asn Trp
                 110                 115                 120

 Tyr Glu Ser Gln Ala Ser Cys Met Ser Gln Asn Ala Ser Leu Leu
                 125                 130                 135

 Lys Val Tyr Ser Lys Glu Asp Gln Asp Leu Leu Lys Leu Val Lys
                 140                 145                 150

 Ser Tyr His Trp Met Gly Leu Val His Ile Pro Thr Asn Gly Ser
                 155                 160                 165

 Trp Gln Trp Glu Asp Gly Ser Ile Leu Ser Pro Asn Leu Leu Thr
                 170                 175                 180

 Ile Ile Glu Met Gln Lys Gly Asp Cys Ala Leu Tyr Ala Ser Ser
                 185                 190                 195

 Phe Lys Gly Tyr Ile Glu Asn Cys Ser Thr Pro Asn Thr Tyr Ile
                 200                 205                 210

 Cys Met Gln Arg Thr Val
                 215

<210> 1439
<211> 1504
<212> DNA
<213> Homo sapien

<400> 1439
 cctaagatga gctttccatg taaatttgta gccagcttcc ttctgatttt 50

 caatgtttct tccaaaggtg cagtctccaa agagattacg aatgccttgg 100

 aaacctgggg tgccttgggt caggacatca acttggacat tcctagtttt 150

 caaatgagtg atgatattga cgatataaaa tgggaaaaaa cttcagacaa 200

 gaaaaagatt gcacaattca gaaaagagaa agagactttc aaggaaaaag 250

 atacatataa gctatttaaa aatggaactc tgaaaattaa gcatctgaag 300

 accgatgatc aggatatcta caaggtatca atatatgata caaaaggaaa 350

 aaatgtgttg gaaaaaatat ttgatttgaa gattcaagag agggtctcaa 400

 aaccaaagat ctcctggact tgtatcaaca caaccctgac ctgtgaggta 450

 atgaatggaa ctgaccccga attaaacctg tatcaagatg ggaaacatct 500

 aaaactttct cagagggtca tcacacacaa gtggaccacc agcctgagtg 550

 caaaattcaa gtgcacagca gggaacaaag tcagcaagga atccagtgtc 600

 gagcctgtca gctgtccaga gaaaggtctg gacatctatc tcatcattgg 650

 catatgtgga ggaggcagcc tcttgatggt ctttgtggca ctgctcgttt 700

 tctatatcac caaaaggaaa aaacagagga gtcggagaaa tgatgaggag 750

 ctggagacaa gagcccacag agtagctact gaagaaaggg gccggaagcc 800

 ccaacaaatt ccagcttcaa cccctcagaa tccagcaact tcccaacatc 850

 ctcctccacc acctggtcat cgttcccagg cacctagtca tcgtcccccg 900

 cctcctggac accgtgttca gcaccagcct cagaagaggc ctcctgctcc 950

 gtcgggcaca caagttcacc agcagaaagg cccgcccctc cccagacctc 1000

 gagttcagcc aaaacctccc catggggcag cagaaaactc attgtcccct 1050

 tcctctaatt aaaaaagata gaaactgtct ttttcaataa aaagcactgt 1100

 ggatttctgc cctcctgatg tgcatatccg tacttccatg aggtgttttc 1150

 tgtgtgcaga acattgtcac ctcctgaggc tgtgggccac agccacctct 1200

 gcatcttcga actcagccat gtggtcaaca tctggagttt ttggtctcct 1250

 cagagagctc catcacacca gtaaggagaa gcaatataag tgtgattgca 1300

 agaatggtag aggaccgagc acagaaatct tagagatttc ttgtcccctc 1350

 tcaggtcatg tgtagatgcg ataaatcaag tgattggtgt gcctgggtct 1400

 cactacaagc agcctatctg cttaagagac tctggagttt cttatgtgcc 1450

 ctggtggaca cttgcccacc atcctgtgag taaaagtgaa ataaaagctt 1500

 tgac 1504

<210> 1440
<211> 351
<212> PRT
<213> Homo sapien

<400> 1440
 Met Ser Phe Pro Cys Lys Phe Val Ala Ser Phe Leu Leu Ile Phe
   1               5                  10                  15

 Asn Val Ser Ser Lys Gly Ala Val Ser Lys Glu Ile Thr Asn Ala
                  20                  25                  30

 Leu Glu Thr Trp Gly Ala Leu Gly Gln Asp Ile Asn Leu Asp Ile
                  35                  40                  45

 Pro Ser Phe Gln Met Ser Asp Asp Ile Asp Asp Ile Lys Trp Glu
                  50                  55                  60

 Lys Thr Ser Asp Lys Lys Lys Ile Ala Gln Phe Arg Lys Glu Lys
                  65                  70                  75

 Glu Thr Phe Lys Glu Lys Asp Thr Tyr Lys Leu Phe Lys Asn Gly
                  80                  85                  90

 Thr Leu Lys Ile Lys His Leu Lys Thr Asp Asp Gln Asp Ile Tyr
                  95                 100                 105

 Lys Val Ser Ile Tyr Asp Thr Lys Gly Lys Asn Val Leu Glu Lys
                 110                 115                 120

 Ile Phe Asp Leu Lys Ile Gln Glu Arg Val Ser Lys Pro Lys Ile
                 125                 130                 135

 Ser Trp Thr Cys Ile Asn Thr Thr Leu Thr Cys Glu Val Met Asn
                 140                 145                 150

 Gly Thr Asp Pro Glu Leu Asn Leu Tyr Gln Asp Gly Lys His Leu
                 155                 160                 165

 Lys Leu Ser Gln Arg Val Ile Thr His Lys Trp Thr Thr Ser Leu
                 170                 175                 180

 Ser Ala Lys Phe Lys Cys Thr Ala Gly Asn Lys Val Ser Lys Glu
                 185                 190                 195

 Ser Ser Val Glu Pro Val Ser Cys Pro Glu Lys Gly Leu Asp Ile
                 200                 205                 210

 Tyr Leu Ile Ile Gly Ile Cys Gly Gly Gly Ser Leu Leu Met Val
                 215                 220                 225

 Phe Val Ala Leu Leu Val Phe Tyr Ile Thr Lys Arg Lys Lys Gln
                 230                 235                 240

 Arg Ser Arg Arg Asn Asp Glu Glu Leu Glu Thr Arg Ala His Arg
                 245                 250                 255

 Val Ala Thr Glu Glu Arg Gly Arg Lys Pro Gln Gln Ile Pro Ala
                 260                 265                 270

 Ser Thr Pro Gln Asn Pro Ala Thr Ser Gln His Pro Pro Pro Pro
                 275                 280                 285

 Pro Gly His Arg Ser Gln Ala Pro Ser His Arg Pro Pro Pro Pro
                 290                 295                 300

 Gly His Arg Val Gln His Gln Pro Gln Lys Arg Pro Pro Ala Pro
                 305                 310                 315

 Ser Gly Thr Gln Val His Gln Gln Lys Gly Pro Pro Leu Pro Arg
                 320                 325                 330

 Pro Arg Val Gln Pro Lys Pro Pro His Gly Ala Ala Glu Asn Ser
                 335                 340                 345

 Leu Ser Pro Ser Ser Asn
                 350

<210> 1441
<211> 5097
<212> DNA
<213> Homo sapien

<400> 1441
 ctgcaggaag gagagaggaa gaggagcaga agggggcagc agcggacgcc 50

 gctaacggcc tccctcggcg ctgacaggct gggccggcgc ccggctcgct 100

 tgggtgttcg cgtcgccact tcggcttctc ggccggtcgg gcccctcggc 150

 ccgggcttgc ggcgcgcgtc ggggctgagg gctgctgcgg cgcagggaga 200

 ggcctggtcc tcgctgccga gggatgtgag tgggagctga gcccacactg 250

 gagggccccc gagggcccag cctggaggtc gttcagagcc gtgcccgccc 300

 cggggcttcg cagaccttga cccgccgggt aggagccgcc cctgcgggct 350

 cgagggcgcg ctctggtcgc ccgatctgtg tagccggttt cagaagcagg 400

 caacaggaac aagatgtgaa ctgtttctct tctgcagaaa aagaggctct 450

 tcctcctcct cccgcgacgg caaatgttct gaaaaagact ctgcatggga 500

 atggcctgcc ttacgatgac agaaatggag ggaacatcca cctcttctat 550

 atatcagaat ggtgatattt ctggaaatgc caattctatg aagcaaatag 600

 atccagttct tcaggtgtat ctttaccatt cccttgggaa atctgaggca 650

 gattatctga cctttccatc tggggagtat gttgcagaag aaatctgtat 700

 tgctgcttct aaagcttgtg gtatcacacc tgtgtatcat aatatgtttg 750

 ctttaatgag tgaaacagaa aggatctggt atccacccaa ccatgtcttc 800

 catatagatg agtcaaccag gcataatgta ctctacagaa taagatttta 850

 ctttcctcgt tggtattgca gtggcagcaa cagagcctat cggcatggaa 900

 tatctcgagg tgctgaagct cctcttcttg atgactttgt catgtcttac 950

 ctctttgctc agtggcggca tgattttgtg cacggatgga taaaagtacc 1000

 tgtgactcat gaaacacagg aagaatgtct tgggatggca gtgttagata 1050

 tgatgagaat agccaaagaa aacgatcaaa ccccactggc catctataac 1100

 tctatcagct acaagacatt cttaccaaaa tgtattcgag caaagatcca 1150

 agactatcat attttgacaa ggaagcgaat aaggtacaga tttcgcagat 1200

 ttattcagca attcagccaa tgcaaagcca ctgccagaaa cttgaaactt 1250

 aagtatctta taaatctgga aactctgcag tctgccttct acacagagaa 1300

 atttgaagta aaagaacctg gaagtggtcc ttcaggtgag gagatttttg 1350

 caaccattat aataactgga aacggtggaa ttcagtggtc aagagggaaa 1400

 cataaagaaa gtgagacact gacagaacag gatttacagt tatattgcga 1450

 ttttcctaat attattgatg tcagtattaa gcaagcaaac caagagggtt 1500

 caaatgaaag ccgagttgta actatccata agcaagatgg taaaaatctg 1550

 gaaattgaac ttagctcatt aagggaagct ttgtctttcg tgtcattaat 1600

 tgatggatat tatagattaa ctgcagatgc acatcattac ctctgtaaag 1650

 aagtagcacc tccagccgtg cttgaaaata tacaaagcaa ctgtcatggc 1700

 ccaatttcga tggattttgc cattagtaaa ctgaagaaag caggtaatca 1750

 gactggactg tatgtacttc gatgcagtcc taaggacttt aataaatatt 1800

 ttttgacttt tgctgtcgag cgagaaaatg tcattgaata taaacactgt 1850

 ttgattacaa aaaatgagaa tgaagagtac aacctcagtg ggacaaagaa 1900

 gaacttcagc agtcttaaag atcttttgaa ttgttaccag atggaaactg 1950

 ttcgctcaga caatataatt ttccagttta ctaaatgctg tcccccaaag 2000

 ccaaaagata aatcaaacct tctagtcttc agaacgaatg gtgtttctga 2050

 tgtaccaacc tcaccaacat tacagaggcc tactcatatg aaccaaatgg 2100

 tgtttcacaa aatcagaaat gaagatttga tatttaatga aagccttggc 2150

 caaggcactt ttacaaagat ttttaaaggc gtacgaagag aagtaggaga 2200

 ctacggtcaa ctgcatgaaa cagaagttct tttaaaagtt ctggataaag 2250

 cacacagaaa ctattcagag tctttctttg aagcagcaag tatgatgagc 2300

 aagctttctc acaagcattt ggttttaaat tatggagtat gtgtctgtgg 2350

 agacgagaat attctggttc aggagtttgt aaaatttgga tcactagata 2400

 catatctgaa aaagaataaa aattgtataa atatattatg gaaacttgaa 2450

 gttgctaaac agttggcatg ggccatgcat tttctagaag aaaacaccct 2500

 tattcatggg aatgtatgtg ccaaaaatat tctgcttatc agagaagaag 2550

 acaggaagac aggaaatcct cctttcatca aacttagtga tcctggcatt 2600

 agtattacag ttttgccaaa ggacattctt caggagagaa taccatgggt 2650

 accacctgaa tgcattgaaa atcctaaaaa tttaaatttg gcaacagaca 2700

 aatggagttt tggtaccact ttgtgggaaa tctgcagtgg aggagataaa 2750

 cctctaagtg ctctggattc tcaaagaaag ctacaatttt atgaagatag 2800

 gcatcagctt cctgcaccaa agtgggcaga attagcaaac cttataaata 2850

 attgtatgga ttatgaacca gatttcaggc cttctttcag agccatcata 2900

 cgagatctta acagtttgtt tactccagat tatgaactat taacagaaaa 2950

 tgacatgtta ccaaatatga ggataggtgc cctagggttt tctggtgcct 3000

 ttgaagaccg ggatcctaca cagtttgaag agagacattt gaaatttcta 3050

 cagcaacttg gcaagggtaa ttttgggagt gtggagatgt gccggtatga 3100

 ccctctacag gacaacactg gggaggtggt cgctgtaaaa aagcttcagc 3150

 atagtactga agagcaccta agagactttg aaagggaaat tgaaatcctg 3200

 aaatccctac agcatgacaa cattgtaaag tacaagggag tgtgctacag 3250

 tgctggtcgg cgtaatctaa aattaattat ggaatattta ccatatggaa 3300

 gtttacgaga ctatcttcaa aaacataaag aacggataga tcacataaaa 3350

 cttctgcagt acacatctca gatatgcaag ggtatggagt atcttggtac 3400

 aaaaaggtat atccacaggg atctggcaac gagaaatata ttggtggaga 3450

 acgagaacag agttaaaatt ggagattttg ggttaaccaa agtcttgcca 3500

 caagacaaag aatactataa agtaaaagaa cctggtgaaa gtcccatatt 3550

 ctggtatgct ccagaatcac tgacagagag caagttttct gtggcctcag 3600

 atgtttggag ctttggagtg gttctgtatg aacttttcac atacattgag 3650

 aagagtaaaa gtccaccagc ggaatttatg cgtatgattg gcaatgacaa 3700

 acaaggacag atgatcgtgt tccatttgat agaacttttg aagaataatg 3750

 gaagattacc aagaccagat ggatgcccag atgagatcta tatgatcatg 3800

 acagaatgct ggaacaataa tgtaaatcaa cgcccctcct ttagggatct 3850

 agctcttcga gtggatcaaa taagggataa catggctgga tgaaagaaat 3900

 gaccttcatt ctgagaccaa agtagattta cagaacaaag ttttatattt 3950

 cacattgctg tggactatta ttacatatat cattattata taaatcatga 4000

 tgctagccag caaagatgtg aaaatatctg ctcaaaactt tcaaagttta 4050

 gtaagttttt cttcatgagg ccaccagtaa aagacattaa tgagaattcc 4100

 ttagcaagga ttttgtaaga agtttcttaa acattgtctg ttaacatcac 4150

 tcttgtctgg caaaagaaaa aaaatagact ttttcaactc agctttttga 4200

 gacctgaaaa aattattatg taaattttgc aatgttaaag atgcacagaa 4250

 tatgtatgta tagtttttac cacagtggat gtataatacc ttggcatctt 4300

 gtgtgatgtt ttacacacat gagggctggt gttcattaat actgttttct 4350

 aatttttcca tagttaatct ataattaatt acttcactat acaaacaaat 4400

 taagatgttc agataattga ataagtacct ttgtgtcctt gttcatttat 4450

 atcgctggcc agcattataa gcaggtgtat acttttagct tgtagttcca 4500

 tgtactgtaa atatttttca cataaaggga acaaatgtct agttttattt 4550

 gtataggaaa tttccctgac cctaaataat acattttgaa atgaaacaag 4600

 cttacaaaga tataatctat tttattatgg tttcccttgt atctatttgt 4650

 ggtgaatgtg ttttttaaat ggaactatct ccaaattttt ctaagactac 4700

 tatgaacagt tttcttttaa aattttgaga ttaagaatgc caggaatatt 4750

 gtcatccttt gagctgctga ctgccaataa cattcttcga tctctgggat 4800

 ttatgctcat gaactaaatt taagcttaag ccataaaata gattagattg 4850

 ttttttaaaa atggatagct cattaagaag tgcagcaggt taagaatttt 4900

 ttcctaaaga ctgtatattt gaggggtttc agaattttgc attgcagtca 4950

 tagaagagat ttatttcctt tttagagggg aaatgaggta aataagtaaa 5000

 aaagtatgct tgttaatttt attcaagaat gccagtagaa aattcataac 5050

 gtgtatcttt aagaaaaatg agcatacatc ttaaatcttt tcaatta 5097

<210> 1442
<211> 1132
<212> PRT
<213> Homo sapien

<400> 1442
 Met Gly Met Ala Cys Leu Thr Met Thr Glu Met Glu Gly Thr Ser
   1               5                  10                  15

 Thr Ser Ser Ile Tyr Gln Asn Gly Asp Ile Ser Gly Asn Ala Asn
                  20                  25                  30

 Ser Met Lys Gln Ile Asp Pro Val Leu Gln Val Tyr Leu Tyr His
                  35                  40                  45

 Ser Leu Gly Lys Ser Glu Ala Asp Tyr Leu Thr Phe Pro Ser Gly
                  50                  55                  60

 Glu Tyr Val Ala Glu Glu Ile Cys Ile Ala Ala Ser Lys Ala Cys
                  65                  70                  75

 Gly Ile Thr Pro Val Tyr His Asn Met Phe Ala Leu Met Ser Glu
                  80                  85                  90

 Thr Glu Arg Ile Trp Tyr Pro Pro Asn His Val Phe His Ile Asp
                  95                 100                 105

 Glu Ser Thr Arg His Asn Val Leu Tyr Arg Ile Arg Phe Tyr Phe
                 110                 115                 120

 Pro Arg Trp Tyr Cys Ser Gly Ser Asn Arg Ala Tyr Arg His Gly
                 125                 130                 135

 Ile Ser Arg Gly Ala Glu Ala Pro Leu Leu Asp Asp Phe Val Met
                 140                 145                 150

 Ser Tyr Leu Phe Ala Gln Trp Arg His Asp Phe Val His Gly Trp
                 155                 160                 165

 Ile Lys Val Pro Val Thr His Glu Thr Gln Glu Glu Cys Leu Gly
                 170                 175                 180

 Met Ala Val Leu Asp Met Met Arg Ile Ala Lys Glu Asn Asp Gln
                 185                 190                 195

 Thr Pro Leu Ala Ile Tyr Asn Ser Ile Ser Tyr Lys Thr Phe Leu
                 200                 205                 210

 Pro Lys Cys Ile Arg Ala Lys Ile Gln Asp Tyr His Ile Leu Thr
                 215                 220                 225

 Arg Lys Arg Ile Arg Tyr Arg Phe Arg Arg Phe Ile Gln Gln Phe
                 230                 235                 240

 Ser Gln Cys Lys Ala Thr Ala Arg Asn Leu Lys Leu Lys Tyr Leu
                 245                 250                 255

 Ile Asn Leu Glu Thr Leu Gln Ser Ala Phe Tyr Thr Glu Lys Phe
                 260                 265                 270

 Glu Val Lys Glu Pro Gly Ser Gly Pro Ser Gly Glu Glu Ile Phe
                 275                 280                 285

 Ala Thr Ile Ile Ile Thr Gly Asn Gly Gly Ile Gln Trp Ser Arg
                 290                 295                 300

 Gly Lys His Lys Glu Ser Glu Thr Leu Thr Glu Gln Asp Leu Gln
                 305                 310                 315

 Leu Tyr Cys Asp Phe Pro Asn Ile Ile Asp Val Ser Ile Lys Gln
                 320                 325                 330

 Ala Asn Gln Glu Gly Ser Asn Glu Ser Arg Val Val Thr Ile His
                 335                 340                 345

 Lys Gln Asp Gly Lys Asn Leu Glu Ile Glu Leu Ser Ser Leu Arg
                 350                 355                 360

 Glu Ala Leu Ser Phe Val Ser Leu Ile Asp Gly Tyr Tyr Arg Leu
                 365                 370                 375

 Thr Ala Asp Ala His His Tyr Leu Cys Lys Glu Val Ala Pro Pro
                 380                 385                 390

 Ala Val Leu Glu Asn Ile Gln Ser Asn Cys His Gly Pro Ile Ser
                 395                 400                 405

 Met Asp Phe Ala Ile Ser Lys Leu Lys Lys Ala Gly Asn Gln Thr
                 410                 415                 420

 Gly Leu Tyr Val Leu Arg Cys Ser Pro Lys Asp Phe Asn Lys Tyr
                 425                 430                 435

 Phe Leu Thr Phe Ala Val Glu Arg Glu Asn Val Ile Glu Tyr Lys
                 440                 445                 450

 His Cys Leu Ile Thr Lys Asn Glu Asn Glu Glu Tyr Asn Leu Ser
                 455                 460                 465

 Gly Thr Lys Lys Asn Phe Ser Ser Leu Lys Asp Leu Leu Asn Cys
                 470                 475                 480

 Tyr Gln Met Glu Thr Val Arg Ser Asp Asn Ile Ile Phe Gln Phe
                 485                 490                 495

 Thr Lys Cys Cys Pro Pro Lys Pro Lys Asp Lys Ser Asn Leu Leu
                 500                 505                 510

 Val Phe Arg Thr Asn Gly Val Ser Asp Val Pro Thr Ser Pro Thr
                 515                 520                 525

 Leu Gln Arg Pro Thr His Met Asn Gln Met Val Phe His Lys Ile
                 530                 535                 540

 Arg Asn Glu Asp Leu Ile Phe Asn Glu Ser Leu Gly Gln Gly Thr
                 545                 550                 555

 Phe Thr Lys Ile Phe Lys Gly Val Arg Arg Glu Val Gly Asp Tyr
                 560                 565                 570

 Gly Gln Leu His Glu Thr Glu Val Leu Leu Lys Val Leu Asp Lys
                 575                 580                 585

 Ala His Arg Asn Tyr Ser Glu Ser Phe Phe Glu Ala Ala Ser Met
                 590                 595                 600

 Met Ser Lys Leu Ser His Lys His Leu Val Leu Asn Tyr Gly Val
                 605                 610                 615

 Cys Val Cys Gly Asp Glu Asn Ile Leu Val Gln Glu Phe Val Lys
                 620                 625                 630

 Phe Gly Ser Leu Asp Thr Tyr Leu Lys Lys Asn Lys Asn Cys Ile
                 635                 640                 645

 Asn Ile Leu Trp Lys Leu Glu Val Ala Lys Gln Leu Ala Trp Ala
                 650                 655                 660

 Met His Phe Leu Glu Glu Asn Thr Leu Ile His Gly Asn Val Cys
                 665                 670                 675

 Ala Lys Asn Ile Leu Leu Ile Arg Glu Glu Asp Arg Lys Thr Gly
                 680                 685                 690

 Asn Pro Pro Phe Ile Lys Leu Ser Asp Pro Gly Ile Ser Ile Thr
                 695                 700                 705

 Val Leu Pro Lys Asp Ile Leu Gln Glu Arg Ile Pro Trp Val Pro
                 710                 715                 720

 Pro Glu Cys Ile Glu Asn Pro Lys Asn Leu Asn Leu Ala Thr Asp
                 725                 730                 735

 Lys Trp Ser Phe Gly Thr Thr Leu Trp Glu Ile Cys Ser Gly Gly
                 740                 745                 750

 Asp Lys Pro Leu Ser Ala Leu Asp Ser Gln Arg Lys Leu Gln Phe
                 755                 760                 765

 Tyr Glu Asp Arg His Gln Leu Pro Ala Pro Lys Trp Ala Glu Leu
                 770                 775                 780

 Ala Asn Leu Ile Asn Asn Cys Met Asp Tyr Glu Pro Asp Phe Arg
                 785                 790                 795

 Pro Ser Phe Arg Ala Ile Ile Arg Asp Leu Asn Ser Leu Phe Thr
                 800                 805                 810

 Pro Asp Tyr Glu Leu Leu Thr Glu Asn Asp Met Leu Pro Asn Met
                 815                 820                 825

 Arg Ile Gly Ala Leu Gly Phe Ser Gly Ala Phe Glu Asp Arg Asp
                 830                 835                 840

 Pro Thr Gln Phe Glu Glu Arg His Leu Lys Phe Leu Gln Gln Leu
                 845                 850                 855

 Gly Lys Gly Asn Phe Gly Ser Val Glu Met Cys Arg Tyr Asp Pro
                 860                 865                 870

 Leu Gln Asp Asn Thr Gly Glu Val Val Ala Val Lys Lys Leu Gln
                 875                 880                 885

 His Ser Thr Glu Glu His Leu Arg Asp Phe Glu Arg Glu Ile Glu
                 890                 895                 900

 Ile Leu Lys Ser Leu Gln His Asp Asn Ile Val Lys Tyr Lys Gly
                 905                 910                 915

 Val Cys Tyr Ser Ala Gly Arg Arg Asn Leu Lys Leu Ile Met Glu
                 920                 925                 930

 Tyr Leu Pro Tyr Gly Ser Leu Arg Asp Tyr Leu Gln Lys His Lys
                 935                 940                 945

 Glu Arg Ile Asp His Ile Lys Leu Leu Gln Tyr Thr Ser Gln Ile
                 950                 955                 960

 Cys Lys Gly Met Glu Tyr Leu Gly Thr Lys Arg Tyr Ile His Arg
                 965                 970                 975

 Asp Leu Ala Thr Arg Asn Ile Leu Val Glu Asn Glu Asn Arg Val
                 980                 985                 990

 Lys Ile Gly Asp Phe Gly Leu Thr Lys Val Leu Pro Gln Asp Lys
                 995                1000                1005

 Glu Tyr Tyr Lys Val Lys Glu Pro Gly Glu Ser Pro Ile Phe Trp
                1010                1015                1020

 Tyr Ala Pro Glu Ser Leu Thr Glu Ser Lys Phe Ser Val Ala Ser
                1025                1030                1035

 Asp Val Trp Ser Phe Gly Val Val Leu Tyr Glu Leu Phe Thr Tyr
                1040                1045                1050

 Ile Glu Lys Ser Lys Ser Pro Pro Ala Glu Phe Met Arg Met Ile
                1055                1060                1065

 Gly Asn Asp Lys Gln Gly Gln Met Ile Val Phe His Leu Ile Glu
                1070                1075                1080

 Leu Leu Lys Asn Asn Gly Arg Leu Pro Arg Pro Asp Gly Cys Pro
                1085                1090                1095

 Asp Glu Ile Tyr Met Ile Met Thr Glu Cys Trp Asn Asn Asn Val
                1100                1105                1110

 Asn Gln Arg Pro Ser Phe Arg Asp Leu Ala Leu Arg Val Asp Gln
                1115                1120                1125

 Ile Arg Asp Asn Met Ala Gly
                1130

<210> 1443
<211> 5097
<212> DNA
<213> Homo sapien

<400> 1443
 ctgcaggaag gagagaggaa gaggagcaga agggggcagc agcggacgcc 50

 gctaacggcc tccctcggcg ctgacaggct gggccggcgc ccggctcgct 100

 tgggtgttcg cgtcgccact tcggcttctc ggccggtcgg gcccctcggc 150

 ccgggcttgc ggcgcgcgtc ggggctgagg gctgctgcgg cgcagggaga 200

 ggcctggtcc tcgctgccga gggatgtgag tgggagctga gcccacactg 250

 gagggccccc gagggcccag cctggaggtc gttcagagcc gtgcccgccc 300

 cggggcttcg cagaccttga cccgccgggt aggagccgcc cctgcgggct 350

 cgagggcgcg ctctggtcgc ccgatctgtg tagccggttt cagaagcagg 400

 caacaggaac aagatgtgaa ctgtttctct tctgcagaaa aagaggctct 450

 tcctcctcct cccgcgacgg caaatgttct gaaaaagact ctgcatggga 500

 atggcctgcc ttacgatgac agaaatggag ggaacatcca cctcttctat 550

 atatcagaat ggtgatattt ctggaaatgc caattctatg aagcaaatag 600

 atccagttct tcaggtgtat ctttaccatt cccttgggaa atctgaggca 650

 gattatctga cctttccatc tggggagtat gttgcagaag aaatctgtat 700

 tgctgcttct aaagcttgtg gtatcacacc tgtgtatcat aatatgtttg 750

 ctttaatgag tgaaacagaa aggatctggt atccacccaa ccatgtcttc 800

 catatagatg agtcaaccag gcataatgta ctctacagaa taagatttta 850

 ctttcctcgt tggtattgca gtggcagcaa cagagcctat cggcatggaa 900

 tatctcgagg tgctgaagct cctcttcttg atgactttgt catgtcttac 950

 ctctttgctc agtggcggca tgattttgtg cacggatgga taaaagtacc 1000

 tgtgactcat gaaacacagg aagaatgtct tgggatggca gtgttagata 1050

 tgatgagaat agccaaagaa aacgatcaaa ccccactggc catctataac 1100

 tctatcagct acaagacatt cttaccaaaa tgtattcgag caaagatcca 1150

 agactatcat attttgacaa ggaagcgaat aaggtacaga tttcgcagat 1200

 ttattcagca attcagccaa tgcaaagcca ctgccagaaa cttgaaactt 1250

 aagtatctta taaatctgga aactctgcag tctgccttct acacagagaa 1300

 atttgaagta aaagaacctg gaagtggtcc ttcaggtgag gagatttttg 1350

 caaccattat aataactgga aacggtggaa ttcagtggtc aagagggaaa 1400

 cataaagaaa gtgagacact gacagaacag gatttacagt tatattgcga 1450

 ttttcctaat attattgatg tcagtattaa gcaagcaaac caagagggtt 1500

 caaatgaaag ccgagttgta actatccata agcaagatgg taaaaatctg 1550

 gaaattgaac ttagctcatt aagggaagct ttgtctttcg tgtcattaat 1600

 tgatggatat tatagattaa ctgcagatgc acatcattac ctctgtaaag 1650

 aagtagcacc tccagccgtg cttgaaaata tacaaagcaa ctgtcatggc 1700

 ccaatttcga tggattttgc cattagtaaa ctgaagaaag caggtaatca 1750

 gactggactg tatgtacttc gatgcagtcc taaggacttt aataaatatt 1800

 ttttgacttt tgctgtcgag cgagaaaatg tcattgaata taaacactgt 1850

 ttgattacaa aaaatgagaa tgaagagtac aacctcagtg ggacaaagaa 1900

 gaacttcagc agtcttaaag atcttttgaa ttgttaccag atggaaactg 1950

 ttcgctcaga caatataatt ttccagttta ctaaatgctg tcccccaaag 2000

 ccaaaagata aatcaaacct tctagtcttc agaacgaatg gtgtttctga 2050

 tgtaccaacc tcaccaacat tacagaggcc tactcatatg aaccaaatgg 2100

 tgtttcacaa aatcagaaat gaagatttga tatttaatga aagccttggc 2150

 caaggcactt ttacaaagat ttttaaaggc gtacgaagag aagtaggaga 2200

 ctacggtcaa ctgcatgaaa cagaagttct tttaaaagtt ctggataaag 2250

 cacacagaaa ctattcagag tctttctttg aagcagcaag tatgatgagc 2300

 aagctttctc acaagcattt ggttttaaat tatggagtat gtgtctgtgg 2350

 agacgagaat attctggttc aggagtttgt aaaatttgga tcactagata 2400

 catatctgaa aaagaataaa aattgtataa atatattatg gaaacttgaa 2450

 gttgctaaac agttggcatg ggccatgcat tttctagaag aaaacaccct 2500

 tattcatggg aatgtatgtg ccaaaaatat tctgcttatc agagaagaag 2550

 acaggaagac aggaaatcct cctttcatca aacttagtga tcctggcatt 2600

 agtattacag ttttgccaaa ggacattctt caggagagaa taccatgggt 2650

 accacctgaa tgcattgaaa atcctaaaaa tttaaatttg gcaacagaca 2700

 aatggagttt tggtaccact ttgtgggaaa tctgcagtgg aggagataaa 2750

 cctctaagtg ctctggattc tcaaagaaag ctacaatttt atgaagatag 2800

 gcatcagctt cctgcaccaa agtgggcaga attagcaaac cttataaata 2850

 attgtatgga ttatgaacca gatttcaggc cttctttcag agccatcata 2900

 cgagatctta acagtttgtt tactccagat tatgaactat taacagaaaa 2950

 tgacatgtta ccaaatatga ggataggtgc cctagggttt tctggtgcct 3000

 ttgaagaccg ggatcctaca cagtttgaag agagacattt gaaatttcta 3050

 cagcaacttg gcaagggtaa ttttgggagt gtggagatgt gccggtatga 3100

 ccctctacag gacaacactg gggaggtggt cgctgtaaaa aagcttcagc 3150

 atagtactga agagcaccta agagactttg aaagggaaat tgaaatcctg 3200

 aaatccctac agcatgacaa cattgtaaag tacaagggag tgtgctacag 3250

 tgctggtcgg cgtaatctaa aattaattat ggaatattta ccatatggaa 3300

 gtttacgaga ctatcttcaa aaacataaag aacggataga tcacataaaa 3350

 cttctgcagt acacatctca gatatgcaag ggtatggagt atcttggtac 3400

 aaaaaggtat atccacaggg atctggcaac gagaaatata ttggtggaga 3450

 acgagaacag agttaaaatt ggagattttg ggttaaccaa agtcttgcca 3500

 caagacaaag aatactataa agtaaaagaa cctggtgaaa gtcccatatt 3550

 ctggtatgct ccagaatcac tgacagagag caagttttct gtggcctcag 3600

 atgtttggag ctttggagtg gttctgtatg aacttttcac atacattgag 3650

 aagagtaaaa gtccaccagc ggaatttatg cgtatgattg gcaatgacaa 3700

 acaaggacag atgatcgtgt tccatttgat agaacttttg aagaataatg 3750

 gaagattacc aagaccagat ggatgcccag atgagatcta tatgatcatg 3800

 acagaatgct ggaacaataa tgtaaatcaa cgcccctcct ttagggatct 3850

 agctcttcga gtggatcaaa taagggataa catggctgga tgaaagaaat 3900

 gaccttcatt ctgagaccaa agtagattta cagaacaaag ttttatattt 3950

 cacattgctg tggactatta ttacatatat cattattata taaatcatga 4000

 tgctagccag caaagatgtg aaaatatctg ctcaaaactt tcaaagttta 4050

 gtaagttttt cttcatgagg ccaccagtaa aagacattaa tgagaattcc 4100

 ttagcaagga ttttgtaaga agtttcttaa acattgtctg ttaacatcac 4150

 tcttgtctgg caaaagaaaa aaaatagact ttttcaactc agctttttga 4200

 gacctgaaaa aattattatg taaattttgc aatgttaaag atgcacagaa 4250

 tatgtatgta tagtttttac cacagtggat gtataatacc ttggcatctt 4300

 gtgtgatgtt ttacacacat gagggctggt gttcattaat actgttttct 4350

 aatttttcca tagttaatct ataattaatt acttcactat acaaacaaat 4400

 taagatgttc agataattga ataagtacct ttgtgtcctt gttcatttat 4450

 atcgctggcc agcattataa gcaggtgtat acttttagct tgtagttcca 4500

 tgtactgtaa atatttttca cataaaggga acaaatgtct agttttattt 4550

 gtataggaaa tttccctgac cctaaataat acattttgaa atgaaacaag 4600

 cttacaaaga tataatctat tttattatgg tttcccttgt atctatttgt 4650

 ggtgaatgtg ttttttaaat ggaactatct ccaaattttt ctaagactac 4700

 tatgaacagt tttcttttaa aattttgaga ttaagaatgc caggaatatt 4750

 gtcatccttt gagctgctga ctgccaataa cattcttcga tctctgggat 4800

 ttatgctcat gaactaaatt taagcttaag ccataaaata gattagattg 4850

 ttttttaaaa atggatagct cattaagaag tgcagcaggt taagaatttt 4900

 ttcctaaaga ctgtatattt gaggggtttc agaattttgc attgcagtca 4950

 tagaagagat ttatttcctt tttagagggg aaatgaggta aataagtaaa 5000

 aaagtatgct tgttaatttt attcaagaat gccagtagaa aattcataac 5050

 gtgtatcttt aagaaaaatg agcatacatc ttaaatcttt tcaatta 5097

<210> 1444
<211> 1132
<212> PRT
<213> Homo sapien

<400> 1444
 Met Gly Met Ala Cys Leu Thr Met Thr Glu Met Glu Gly Thr Ser
   1               5                  10                  15

 Thr Ser Ser Ile Tyr Gln Asn Gly Asp Ile Ser Gly Asn Ala Asn
                  20                  25                  30

 Ser Met Lys Gln Ile Asp Pro Val Leu Gln Val Tyr Leu Tyr His
                  35                  40                  45

 Ser Leu Gly Lys Ser Glu Ala Asp Tyr Leu Thr Phe Pro Ser Gly
                  50                  55                  60

 Glu Tyr Val Ala Glu Glu Ile Cys Ile Ala Ala Ser Lys Ala Cys
                  65                  70                  75

 Gly Ile Thr Pro Val Tyr His Asn Met Phe Ala Leu Met Ser Glu
                  80                  85                  90

 Thr Glu Arg Ile Trp Tyr Pro Pro Asn His Val Phe His Ile Asp
                  95                 100                 105

 Glu Ser Thr Arg His Asn Val Leu Tyr Arg Ile Arg Phe Tyr Phe
                 110                 115                 120

 Pro Arg Trp Tyr Cys Ser Gly Ser Asn Arg Ala Tyr Arg His Gly
                 125                 130                 135

 Ile Ser Arg Gly Ala Glu Ala Pro Leu Leu Asp Asp Phe Val Met
                 140                 145                 150

 Ser Tyr Leu Phe Ala Gln Trp Arg His Asp Phe Val His Gly Trp
                 155                 160                 165

 Ile Lys Val Pro Val Thr His Glu Thr Gln Glu Glu Cys Leu Gly
                 170                 175                 180

 Met Ala Val Leu Asp Met Met Arg Ile Ala Lys Glu Asn Asp Gln
                 185                 190                 195

 Thr Pro Leu Ala Ile Tyr Asn Ser Ile Ser Tyr Lys Thr Phe Leu
                 200                 205                 210

 Pro Lys Cys Ile Arg Ala Lys Ile Gln Asp Tyr His Ile Leu Thr
                 215                 220                 225

 Arg Lys Arg Ile Arg Tyr Arg Phe Arg Arg Phe Ile Gln Gln Phe
                 230                 235                 240

 Ser Gln Cys Lys Ala Thr Ala Arg Asn Leu Lys Leu Lys Tyr Leu
                 245                 250                 255

 Ile Asn Leu Glu Thr Leu Gln Ser Ala Phe Tyr Thr Glu Lys Phe
                 260                 265                 270

 Glu Val Lys Glu Pro Gly Ser Gly Pro Ser Gly Glu Glu Ile Phe
                 275                 280                 285

 Ala Thr Ile Ile Ile Thr Gly Asn Gly Gly Ile Gln Trp Ser Arg
                 290                 295                 300

 Gly Lys His Lys Glu Ser Glu Thr Leu Thr Glu Gln Asp Leu Gln
                 305                 310                 315

 Leu Tyr Cys Asp Phe Pro Asn Ile Ile Asp Val Ser Ile Lys Gln
                 320                 325                 330

 Ala Asn Gln Glu Gly Ser Asn Glu Ser Arg Val Val Thr Ile His
                 335                 340                 345

 Lys Gln Asp Gly Lys Asn Leu Glu Ile Glu Leu Ser Ser Leu Arg
                 350                 355                 360

 Glu Ala Leu Ser Phe Val Ser Leu Ile Asp Gly Tyr Tyr Arg Leu
                 365                 370                 375

 Thr Ala Asp Ala His His Tyr Leu Cys Lys Glu Val Ala Pro Pro
                 380                 385                 390

 Ala Val Leu Glu Asn Ile Gln Ser Asn Cys His Gly Pro Ile Ser
                 395                 400                 405

 Met Asp Phe Ala Ile Ser Lys Leu Lys Lys Ala Gly Asn Gln Thr
                 410                 415                 420

 Gly Leu Tyr Val Leu Arg Cys Ser Pro Lys Asp Phe Asn Lys Tyr
                 425                 430                 435

 Phe Leu Thr Phe Ala Val Glu Arg Glu Asn Val Ile Glu Tyr Lys
                 440                 445                 450

 His Cys Leu Ile Thr Lys Asn Glu Asn Glu Glu Tyr Asn Leu Ser
                 455                 460                 465

 Gly Thr Lys Lys Asn Phe Ser Ser Leu Lys Asp Leu Leu Asn Cys
                 470                 475                 480

 Tyr Gln Met Glu Thr Val Arg Ser Asp Asn Ile Ile Phe Gln Phe
                 485                 490                 495

 Thr Lys Cys Cys Pro Pro Lys Pro Lys Asp Lys Ser Asn Leu Leu
                 500                 505                 510

 Val Phe Arg Thr Asn Gly Val Ser Asp Val Pro Thr Ser Pro Thr
                 515                 520                 525

 Leu Gln Arg Pro Thr His Met Asn Gln Met Val Phe His Lys Ile
                 530                 535                 540

 Arg Asn Glu Asp Leu Ile Phe Asn Glu Ser Leu Gly Gln Gly Thr
                 545                 550                 555

 Phe Thr Lys Ile Phe Lys Gly Val Arg Arg Glu Val Gly Asp Tyr
                 560                 565                 570

 Gly Gln Leu His Glu Thr Glu Val Leu Leu Lys Val Leu Asp Lys
                 575                 580                 585

 Ala His Arg Asn Tyr Ser Glu Ser Phe Phe Glu Ala Ala Ser Met
                 590                 595                 600

 Met Ser Lys Leu Ser His Lys His Leu Val Leu Asn Tyr Gly Val
                 605                 610                 615

 Cys Val Cys Gly Asp Glu Asn Ile Leu Val Gln Glu Phe Val Lys
                 620                 625                 630

 Phe Gly Ser Leu Asp Thr Tyr Leu Lys Lys Asn Lys Asn Cys Ile
                 635                 640                 645

 Asn Ile Leu Trp Lys Leu Glu Val Ala Lys Gln Leu Ala Trp Ala
                 650                 655                 660

 Met His Phe Leu Glu Glu Asn Thr Leu Ile His Gly Asn Val Cys
                 665                 670                 675

 Ala Lys Asn Ile Leu Leu Ile Arg Glu Glu Asp Arg Lys Thr Gly
                 680                 685                 690

 Asn Pro Pro Phe Ile Lys Leu Ser Asp Pro Gly Ile Ser Ile Thr
                 695                 700                 705

 Val Leu Pro Lys Asp Ile Leu Gln Glu Arg Ile Pro Trp Val Pro
                 710                 715                 720

 Pro Glu Cys Ile Glu Asn Pro Lys Asn Leu Asn Leu Ala Thr Asp
                 725                 730                 735

 Lys Trp Ser Phe Gly Thr Thr Leu Trp Glu Ile Cys Ser Gly Gly
                 740                 745                 750

 Asp Lys Pro Leu Ser Ala Leu Asp Ser Gln Arg Lys Leu Gln Phe
                 755                 760                 765

 Tyr Glu Asp Arg His Gln Leu Pro Ala Pro Lys Trp Ala Glu Leu
                 770                 775                 780

 Ala Asn Leu Ile Asn Asn Cys Met Asp Tyr Glu Pro Asp Phe Arg
                 785                 790                 795

 Pro Ser Phe Arg Ala Ile Ile Arg Asp Leu Asn Ser Leu Phe Thr
                 800                 805                 810

 Pro Asp Tyr Glu Leu Leu Thr Glu Asn Asp Met Leu Pro Asn Met
                 815                 820                 825

 Arg Ile Gly Ala Leu Gly Phe Ser Gly Ala Phe Glu Asp Arg Asp
                 830                 835                 840

 Pro Thr Gln Phe Glu Glu Arg His Leu Lys Phe Leu Gln Gln Leu
                 845                 850                 855

 Gly Lys Gly Asn Phe Gly Ser Val Glu Met Cys Arg Tyr Asp Pro
                 860                 865                 870

 Leu Gln Asp Asn Thr Gly Glu Val Val Ala Val Lys Lys Leu Gln
                 875                 880                 885

 His Ser Thr Glu Glu His Leu Arg Asp Phe Glu Arg Glu Ile Glu
                 890                 895                 900

 Ile Leu Lys Ser Leu Gln His Asp Asn Ile Val Lys Tyr Lys Gly
                 905                 910                 915

 Val Cys Tyr Ser Ala Gly Arg Arg Asn Leu Lys Leu Ile Met Glu
                 920                 925                 930

 Tyr Leu Pro Tyr Gly Ser Leu Arg Asp Tyr Leu Gln Lys His Lys
                 935                 940                 945

 Glu Arg Ile Asp His Ile Lys Leu Leu Gln Tyr Thr Ser Gln Ile
                 950                 955                 960

 Cys Lys Gly Met Glu Tyr Leu Gly Thr Lys Arg Tyr Ile His Arg
                 965                 970                 975

 Asp Leu Ala Thr Arg Asn Ile Leu Val Glu Asn Glu Asn Arg Val
                 980                 985                 990

 Lys Ile Gly Asp Phe Gly Leu Thr Lys Val Leu Pro Gln Asp Lys
                 995                1000                1005

 Glu Tyr Tyr Lys Val Lys Glu Pro Gly Glu Ser Pro Ile Phe Trp
                1010                1015                1020

 Tyr Ala Pro Glu Ser Leu Thr Glu Ser Lys Phe Ser Val Ala Ser
                1025                1030                1035

 Asp Val Trp Ser Phe Gly Val Val Leu Tyr Glu Leu Phe Thr Tyr
                1040                1045                1050

 Ile Glu Lys Ser Lys Ser Pro Pro Ala Glu Phe Met Arg Met Ile
                1055                1060                1065

 Gly Asn Asp Lys Gln Gly Gln Met Ile Val Phe His Leu Ile Glu
                1070                1075                1080

 Leu Leu Lys Asn Asn Gly Arg Leu Pro Arg Pro Asp Gly Cys Pro
                1085                1090                1095

 Asp Glu Ile Tyr Met Ile Met Thr Glu Cys Trp Asn Asn Asn Val
                1100                1105                1110

 Asn Gln Arg Pro Ser Phe Arg Asp Leu Ala Leu Arg Val Asp Gln
                1115                1120                1125

 Ile Arg Asp Asn Met Ala Gly
                1130

<210> 1445
<211> 4932
<212> DNA
<213> Homo sapien

<400> 1445
 ggcagggcac acctggattg cattagaatg agactcacta cccagttcag 50

 gtgtgttgcg ttgtgggtct ccggcacatt tcagaggctg attaggaccc 100

 tgaccccaca ctggggttta cacccctaaa agcaggtgtg tcccgtggca 150

 actgagtggg tgcgtgaaaa ggggggatca tcaattacca gctggagcaa 200

 tcgaatcggt taaatgtgaa tcaagtcaca gtgcttcctt aacccaacct 250

 ctctgttggg gtcagccaca gcctaaaccg cctgccgttc agcctgagag 300

 gctgctgcta gcctgctcac gcatgcagcc cgggctgcag aggaagtgtg 350

 gggaggaagg aagtgggtat agaagggtgc tgagatgtgg gtcttgaaga 400

 gaatagccat aacgtctttg tcactaaaat gttccccagg ggccttcggc 450

 gagtcttttt gtttggtttt ttgtttttaa tctgtggctc ttgataattt 500

 atctagtggt tgcctacacc tgaaaaacaa gacacagtgt ttaactatca 550

 acgaaagaac tggacggctc cccgccgcag tcccactccc cgagtttgtg 600

 gctggcattt gggccacgcc gggctgggcg gctcacagcg aggggcgcgc 650

 agtttggggt cacacagctc cgcttctagg ccccaaccac cgttaaaagg 700

 ggaagcccgt gccccatcag gtccgctctt gctgagccca gagccatccc 750

 gcgctctgcg ggctgggagg cccgggccag acgcgagtcc tgcgcagccg 800

 aggttcccca gcgccccctg cagccgcgcg taggcagaga cggagcccgg 850

 ccctgcgcct ccgcaccacg cccgggaccc cacccagcgg cccgtacccg 900

 gagaagcagc gcgagcaccc gaagctcccg gctcggcggc agaaaccggg 950

 agtggggccg ggcgagtgcg cggcatccca ggccggcccg aacgtccgcc 1000

 cgcggtgggc cgacttcccc tcctcttccc tctctccttc ctttagcccg 1050

 ctggcgccgg acacgctgcg cctcatctct tggggcgttc ttccccgttg 1100

 gccaaccgtc gcatcccgtg caactttggg gtagtggccg cttagtgttg 1150

 aatgttcccc accgagagcg catggcttgg gaagcgaggc gcgaacccgg 1200

 gccccgaagc cgccgtccgg gagacggtga tgctgttgct gtgcctgggg 1250

 gtcccgaccg gccgccccta caacgtggac actgagagcg cgctgcttta 1300

 ccagggcccc cacaacacgc tgttcggcta ctcggtcgtg ctgcacagcc 1350

 acggggcgaa ccgatggctc ctagtgggtg cgcccactgc caactggctc 1400

 gccaacgctt cagtgatcaa tcccggggcg atttacagat gcaggatcgg 1450

 aaagaatccc ggccagacgt gcgaacagct ccagctgggt agccctaatg 1500

 gagaaccttg tggaaagact tgtttggaag agagagacaa tcagtggttg 1550

 ggggtcacac tttccagaca gccaggagaa aatggatcca tcgtgacttg 1600

 tgggcataga tggaaaaata tattttacat aaagaatgaa aataagctcc 1650

 ccactggtgg ttgctatgga gtgccccctg atttacgaac agaactgagt 1700

 aaaagaatag ctccgtgtta tcaagattat gtgaaaaaat ttggagaaaa 1750

 ttttgcatca tgtcaagctg gaatatccag tttttacaca aaggatttaa 1800

 ttgtgatggg ggccccagga tcatcttact ggactggctc tctttttgtc 1850

 tacaatataa ctacaaataa atacaaggct tttttagaca aacaaaatca 1900

 agtaaaattt ggaagttatt taggatattc agtcggagct ggtcattttc 1950

 ggagccagca tactaccgaa gtagtcggag gagctcctca acatgagcag 2000

 attggtaagg catatatatt cagcattgat gaaaaagaac taaatatctt 2050

 acatgaaatg aaaggtaaaa agcttggatc gtactttgga gcttctgtct 2100

 gtgctgtgga cctcaatgca gatggcttct cagatctgct cgtgggagca 2150

 cccatgcaga gcaccatcag agaggaagga agagtgtttg tgtacatcaa 2200

 ctctggctcg ggagcagtaa tgaatgcaat ggaaacaaac ctcgttggaa 2250

 gtgacaaata tgctgcaaga tttggggaat ctatagttaa tcttggcgac 2300

 attgacaatg atggctttga agatgttgct atcggagctc cacaagaaga 2350

 tgacttgcaa ggtgctattt atatttacaa tggccgtgca gatgggatct 2400

 cgtcaacctt ctcacagaga attgaaggac ttcagatcag caaatcgtta 2450

 agtatgtttg gacagtctat atcaggacaa attgatgcag ataataatgg 2500

 ctatgtagat gtagcagttg gtgcttttcg gtctgattct gctgtcttgc 2550

 taaggacaag acctgtagta attgttgacg cttctttaag ccaccctgag 2600

 tcagtaaata gaacgaaatt tgactgtgtt gaaaatggat ggccttctgt 2650

 gtgcatagat ctaacacttt gtttctcata taagggcaag gaagttccag 2700

 gttacattgt tttgttttat aacatgagtt tggatgtgaa cagaaaggca 2750

 gagtctccac caagattcta tttctcttct aatggaactt ctgacgtgat 2800

 tacaggaagc atacaggtgt ccagcagaga agctaactgt agaacacatc 2850

 aagcatttat gcggaaagat gtgcgggaca tcctcacccc aattcagatt 2900

 gaagctgctt accaccttgg tcctcatgtc atcagtaaac gaagtacaga 2950

 ggaattccca ccacttcagc caattcttca gcagaagaaa gaaaaagaca 3000

 taatgaaaaa aacaataaac tttgcaaggt tttgtgccca tgaaaattgt 3050

 tctgctgatt tacaggtttc tgcaaagatt gggtttttga agccccatga 3100

 aaataaaaca tatcttgctg ttgggagtat gaagacattg atgttgaatg 3150

 tgtccttgtt taatgctgga gatgatgcat atgaaacgac tctacatgtc 3200

 aaactacccg tgggtcttta tttcattaag attttagagc tggaagagaa 3250

 gcaaataaac tgtgaagtca cagataactc tggcgtggta caacttgact 3300

 gcagtattgg ctatatatat gtagatcatc tctcaaggat agatattagc 3350

 tttctcctgg atgtgagctc actcagcaga gcggaagagg acctcagtat 3400

 cacagtgcat gctacctgtg aaaatgaaga ggaaatggac aatctaaagc 3450

 acagcagagt gactgtagca atacctttaa aatatgaggt taagctgact 3500

 gttcatgggt ttgtaaaccc aacttcattt gtgtatggat caaatgatga 3550

 aaatgagcct gaaacgtgca tggtggagaa aatgaactta actttccatg 3600

 ttatcaacac tggcaatagt atggctccca atgttagtgt ggaaataatg 3650

 gtaccaaatt cttttagccc ccaaactgat aagctgttca acattttgga 3700

 tgtccagact actactggag aatgccactt tgaaaattat caaagagtgt 3750

 gtgcattaga gcagcaaaag agtgcaatgc agaccttgaa aggcatagtc 3800

 cggttcttgt ccaagactga taagaggcta ttgtactgca taaaagctga 3850

 tccacattgt ttaaatttct tgtgtaattt tgggaaaatg gaaagtggaa 3900

 aagaagccag tgttcatatc caactggaag gccggccatc cattttagaa 3950

 atggatgaga cttcagcact caagtttgaa ataagagcaa caggttttcc 4000

 agagccaaat ccaagagtaa ttgaactaaa caaggatgag aatgttgcgc 4050

 atgttctact ggaaggacta catcatcaaa gacccaaacg ttatttcacc 4100

 atagtgatta tttcaagtag cttgctactt ggacttattg tacttctgtt 4150

 gatctcatat gttatgtgga aggctggctt ctttaaaaga caatacaaat 4200

 ctatcctaca agaagaaaac agaagagaca gttggagtta tatcaacagt 4250

 aaaagcaatg atgattaagg acttctttca aattgagaga atggaaaaca 4300

 gactcaggtt gtagtaaaga aatttaaaag acactgttta caagaaaaaa 4350

 tgaattttgt ttggacttct tttactcatg atcttgtgac atattatgtc 4400

 ttcatgcaag gggaaaatct cagcaatgat tactctttga gatagaagaa 4450

 ctgcaaaggt aataatacag ccaaagataa tctctcagct tttaaatggg 4500

 tagagaaaca ctaaagcatt caatttattc aagaaaagta agcccttgaa 4550

 gatatcttga aatgaaagta taactgagtt aaattatact ggagaagtct 4600

 tagacttgaa atactactta ccatatgtgc ttgcctcagt aaaatgaacc 4650

 ccactgggtg ggcagaggtt catttcaaat acatctttga tacttgttca 4700

 aaatatgttc tttaaaaata taatttttta gagagctgtt cccaaatttt 4750

 ctaacgagtg gaccattatc actttaaagc cctttattta taatacattt 4800

 cctacgggct gtgttccaac aaccattttt tttcagcaga ctatgaatat 4850

 tatagtatta taggccaaac tggcaaactt cagactgaac atgtacactg 4900

 gtttgagctt agtgaaatga cttccggaat ct 4932

<210> 1446
<211> 1038
<212> PRT
<213> Homo sapien

<400> 1446
 Met Phe Pro Thr Glu Ser Ala Trp Leu Gly Lys Arg Gly Ala Asn
   1               5                  10                  15

 Pro Gly Pro Glu Ala Ala Val Arg Glu Thr Val Met Leu Leu Leu
                  20                  25                  30

 Cys Leu Gly Val Pro Thr Gly Arg Pro Tyr Asn Val Asp Thr Glu
                  35                  40                  45

 Ser Ala Leu Leu Tyr Gln Gly Pro His Asn Thr Leu Phe Gly Tyr
                  50                  55                  60

 Ser Val Val Leu His Ser His Gly Ala Asn Arg Trp Leu Leu Val
                  65                  70                  75

 Gly Ala Pro Thr Ala Asn Trp Leu Ala Asn Ala Ser Val Ile Asn
                  80                  85                  90

 Pro Gly Ala Ile Tyr Arg Cys Arg Ile Gly Lys Asn Pro Gly Gln
                  95                 100                 105

 Thr Cys Glu Gln Leu Gln Leu Gly Ser Pro Asn Gly Glu Pro Cys
                 110                 115                 120

 Gly Lys Thr Cys Leu Glu Glu Arg Asp Asn Gln Trp Leu Gly Val
                 125                 130                 135

 Thr Leu Ser Arg Gln Pro Gly Glu Asn Gly Ser Ile Val Thr Cys
                 140                 145                 150

 Gly His Arg Trp Lys Asn Ile Phe Tyr Ile Lys Asn Glu Asn Lys
                 155                 160                 165

 Leu Pro Thr Gly Gly Cys Tyr Gly Val Pro Pro Asp Leu Arg Thr
                 170                 175                 180

 Glu Leu Ser Lys Arg Ile Ala Pro Cys Tyr Gln Asp Tyr Val Lys
                 185                 190                 195

 Lys Phe Gly Glu Asn Phe Ala Ser Cys Gln Ala Gly Ile Ser Ser
                 200                 205                 210

 Phe Tyr Thr Lys Asp Leu Ile Val Met Gly Ala Pro Gly Ser Ser
                 215                 220                 225

 Tyr Trp Thr Gly Ser Leu Phe Val Tyr Asn Ile Thr Thr Asn Lys
                 230                 235                 240

 Tyr Lys Ala Phe Leu Asp Lys Gln Asn Gln Val Lys Phe Gly Ser
                 245                 250                 255

 Tyr Leu Gly Tyr Ser Val Gly Ala Gly His Phe Arg Ser Gln His
                 260                 265                 270

 Thr Thr Glu Val Val Gly Gly Ala Pro Gln His Glu Gln Ile Gly
                 275                 280                 285

 Lys Ala Tyr Ile Phe Ser Ile Asp Glu Lys Glu Leu Asn Ile Leu
                 290                 295                 300

 His Glu Met Lys Gly Lys Lys Leu Gly Ser Tyr Phe Gly Ala Ser
                 305                 310                 315

 Val Cys Ala Val Asp Leu Asn Ala Asp Gly Phe Ser Asp Leu Leu
                 320                 325                 330

 Val Gly Ala Pro Met Gln Ser Thr Ile Arg Glu Glu Gly Arg Val
                 335                 340                 345

 Phe Val Tyr Ile Asn Ser Gly Ser Gly Ala Val Met Asn Ala Met
                 350                 355                 360

 Glu Thr Asn Leu Val Gly Ser Asp Lys Tyr Ala Ala Arg Phe Gly
                 365                 370                 375

 Glu Ser Ile Val Asn Leu Gly Asp Ile Asp Asn Asp Gly Phe Glu
                 380                 385                 390

 Asp Val Ala Ile Gly Ala Pro Gln Glu Asp Asp Leu Gln Gly Ala
                 395                 400                 405

 Ile Tyr Ile Tyr Asn Gly Arg Ala Asp Gly Ile Ser Ser Thr Phe
                 410                 415                 420

 Ser Gln Arg Ile Glu Gly Leu Gln Ile Ser Lys Ser Leu Ser Met
                 425                 430                 435

 Phe Gly Gln Ser Ile Ser Gly Gln Ile Asp Ala Asp Asn Asn Gly
                 440                 445                 450

 Tyr Val Asp Val Ala Val Gly Ala Phe Arg Ser Asp Ser Ala Val
                 455                 460                 465

 Leu Leu Arg Thr Arg Pro Val Val Ile Val Asp Ala Ser Leu Ser
                 470                 475                 480

 His Pro Glu Ser Val Asn Arg Thr Lys Phe Asp Cys Val Glu Asn
                 485                 490                 495

 Gly Trp Pro Ser Val Cys Ile Asp Leu Thr Leu Cys Phe Ser Tyr
                 500                 505                 510

 Lys Gly Lys Glu Val Pro Gly Tyr Ile Val Leu Phe Tyr Asn Met
                 515                 520                 525

 Ser Leu Asp Val Asn Arg Lys Ala Glu Ser Pro Pro Arg Phe Tyr
                 530                 535                 540

 Phe Ser Ser Asn Gly Thr Ser Asp Val Ile Thr Gly Ser Ile Gln
                 545                 550                 555

 Val Ser Ser Arg Glu Ala Asn Cys Arg Thr His Gln Ala Phe Met
                 560                 565                 570

 Arg Lys Asp Val Arg Asp Ile Leu Thr Pro Ile Gln Ile Glu Ala
                 575                 580                 585

 Ala Tyr His Leu Gly Pro His Val Ile Ser Lys Arg Ser Thr Glu
                 590                 595                 600

 Glu Phe Pro Pro Leu Gln Pro Ile Leu Gln Gln Lys Lys Glu Lys
                 605                 610                 615

 Asp Ile Met Lys Lys Thr Ile Asn Phe Ala Arg Phe Cys Ala His
                 620                 625                 630

 Glu Asn Cys Ser Ala Asp Leu Gln Val Ser Ala Lys Ile Gly Phe
                 635                 640                 645

 Leu Lys Pro His Glu Asn Lys Thr Tyr Leu Ala Val Gly Ser Met
                 650                 655                 660

 Lys Thr Leu Met Leu Asn Val Ser Leu Phe Asn Ala Gly Asp Asp
                 665                 670                 675

 Ala Tyr Glu Thr Thr Leu His Val Lys Leu Pro Val Gly Leu Tyr
                 680                 685                 690

 Phe Ile Lys Ile Leu Glu Leu Glu Glu Lys Gln Ile Asn Cys Glu
                 695                 700                 705

 Val Thr Asp Asn Ser Gly Val Val Gln Leu Asp Cys Ser Ile Gly
                 710                 715                 720

 Tyr Ile Tyr Val Asp His Leu Ser Arg Ile Asp Ile Ser Phe Leu
                 725                 730                 735

 Leu Asp Val Ser Ser Leu Ser Arg Ala Glu Glu Asp Leu Ser Ile
                 740                 745                 750

 Thr Val His Ala Thr Cys Glu Asn Glu Glu Glu Met Asp Asn Leu
                 755                 760                 765

 Lys His Ser Arg Val Thr Val Ala Ile Pro Leu Lys Tyr Glu Val
                 770                 775                 780

 Lys Leu Thr Val His Gly Phe Val Asn Pro Thr Ser Phe Val Tyr
                 785                 790                 795

 Gly Ser Asn Asp Glu Asn Glu Pro Glu Thr Cys Met Val Glu Lys
                 800                 805                 810

 Met Asn Leu Thr Phe His Val Ile Asn Thr Gly Asn Ser Met Ala
                 815                 820                 825

 Pro Asn Val Ser Val Glu Ile Met Val Pro Asn Ser Phe Ser Pro
                 830                 835                 840

 Gln Thr Asp Lys Leu Phe Asn Ile Leu Asp Val Gln Thr Thr Thr
                 845                 850                 855

 Gly Glu Cys His Phe Glu Asn Tyr Gln Arg Val Cys Ala Leu Glu
                 860                 865                 870

 Gln Gln Lys Ser Ala Met Gln Thr Leu Lys Gly Ile Val Arg Phe
                 875                 880                 885

 Leu Ser Lys Thr Asp Lys Arg Leu Leu Tyr Cys Ile Lys Ala Asp
                 890                 895                 900

 Pro His Cys Leu Asn Phe Leu Cys Asn Phe Gly Lys Met Glu Ser
                 905                 910                 915

 Gly Lys Glu Ala Ser Val His Ile Gln Leu Glu Gly Arg Pro Ser
                 920                 925                 930

 Ile Leu Glu Met Asp Glu Thr Ser Ala Leu Lys Phe Glu Ile Arg
                 935                 940                 945

 Ala Thr Gly Phe Pro Glu Pro Asn Pro Arg Val Ile Glu Leu Asn
                 950                 955                 960

 Lys Asp Glu Asn Val Ala His Val Leu Leu Glu Gly Leu His His
                 965                 970                 975

 Gln Arg Pro Lys Arg Tyr Phe Thr Ile Val Ile Ile Ser Ser Ser
                 980                 985                 990

 Leu Leu Leu Gly Leu Ile Val Leu Leu Leu Ile Ser Tyr Val Met
                 995                1000                1005

 Trp Lys Ala Gly Phe Phe Lys Arg Gln Tyr Lys Ser Ile Leu Gln
                1010                1015                1020

 Glu Glu Asn Arg Arg Asp Ser Trp Ser Tyr Ile Asn Ser Lys Ser
                1025                1030                1035

 Asn Asp Asp


<210> 1447
<211> 2502
<212> DNA
<213> Homo sapien

<400> 1447
 gaattcgtgg gtcgtgctgc gtcgacaacg gtagtgacgc gtattgcctg 50

 gaggatggcg gacgccggca ttcgccgcgt ggttcccagc gacctgtatc 100

 ccctcgtgct cggcttcctg cgcgataacc aactctcaga ggtggccaat 150

 aagttcgcca aagcgacagg agctacacag caggatgcca atgcctcttc 200

 cctcttagac atctatagct tctggctcaa gtctgccaag gtcccagagc 250

 gaaagttaca ggcaaatgga ccagtggcta agaaagctaa gaagaaggcc 300

 tcatccagtg acagtgagga cagcagcgag gaggaggagg aagttcaagg 350

 gcctccagca aagaaggctg ctgtacctgc caagcgagtc ggtctgcctc 400

 ctgggaaggc tgcagccaaa gcatcagaga gtagcagcag tgaagagtcc 450

 agagatgatg atgatgagga ggaccaaaag aaacagcctg tccagaaggg 500

 agttaagccc caagccaagg cagccaaagc tcctcctaag aaggccaaga 550

 gctctgattc tgattctgac tcaagctccg aggatgagcc accaaagaac 600

 cagaagccaa agataacacc tgtgacagtt aaagctcaga ctaaagcccc 650

 tcccaaacca gctcgagcag cacctaaaat agccaatggt aaagcagcca 700

 gtagcagcag tagcagcagc agcagcagta gcagtgatga ctcagaggag 750

 gagaaggcag cagccacccc caagaagact gtacctaaaa agcaagttgt 800

 ggccaaagcc ccagtgaaag cagctaccac ccctacccgg aagagttcta 850

 gcagtgagga ttcctccagt gacgaggaag aggagcaaaa aaaacccatg 900

 aaaaataaac caggtcccta cagttacgcc cccccgcctt ctgctccccc 950

 accaaagaag tctctgggaa cccagcctcc caagaaggct gtggagaagc 1000

 agcagcctgt ggaaagcagt gaagacagca gtgatgagtc tgattcaagt 1050

 tctgaagaag agaagaaacc cccaactaag gcagtagtct ctaaagcaac 1100

 cactaaacca cctccagcaa agaaagcagc agagagctct tcagacagct 1150

 cagactctga cagctctgag gatgatgaag ctccttctaa gccagctggt 1200

 accaccaaga attcttcaaa taagccagct gtcaccacca agtcacctgc 1250

 agtgaagcca gctgcagccc ccaagcaacc tgtgggcggt ggccagaagc 1300

 ttctgacgag aaaggctgac agcagctcca gcgaggaaga gagcagctcc 1350

 agtgaggagg agaagacaaa gaagatggtg gccaccacta agcccaaggc 1400

 gactgccaaa gcagctctat ctctgcctgc caagcaggct cctcagggta 1450

 gtagggacag cagctctgat tcagacagct ccagcagtga ggaggaggaa 1500

 gagaagacat ctaagtctgc agttaagaag aagccacaga aggtagcagg 1550

 aggtgcagcc ccttccaagc cagcctctgc aaagaaagga aaggctgaga 1600

 gcagcaacag ttcttcttct gatgactcca gtgaggaaga ggaagagaag 1650

 ctcaagggca agggctctcc aagaccacaa gcccccaagg ccaatggcac 1700

 ctctgcactg actgcccaga atggaaaagc agctaagaac agtgaggagg 1750

 aggaagaaga aaagaaaaag gcggcagtgg tagtttccaa atcaggttca 1800

 ttaaagaagc ggaagcagaa tgaggctgcc aaggaggcag agactcctca 1850

 ggccaagaag ataaagcttc agacccctaa cacatttcca aaaaggaaga 1900

 aaggagaaaa aagggcatca tccccattcc gaagggtcag ggaggaggaa 1950

 attgaggtgg attcacgagt tgcggacaac tcctttgatg ccaagcgagg 2000

 tgcagccgga gactggggag agcgagccaa tcaggttttg aagttcacca 2050

 aaggcaagtc ctttcggcat gagaaaacca agaagaagcg gggcagctac 2100

 cggggaggct caatctctgt ccaggtcaat tctattaagt ttgacagcga 2150

 gtgacctgag gccatcttcg gtgaagcaag ggtgatgatc ggagactact 2200

 tactttctcc agtggacctg ggaaccctca ggtctctagg tgagggtctt 2250

 gatgaggaca gaagtttaga gtaggtccta agactttaca gtgtaacatc 2300

 ctctctggtc cttttctgtg ttcctagttt tgtacagact tgtttttgag 2350

 tgttgagtag cagggacaaa ataagggaat gttatttttt aagaaaattc 2400

 attttcattg ttgtctcctt ccttttctgt gaaagtcctc atactgagaa 2450

 atttgtatat tttatattaa atcacttact attgaaaaaa aaaaaggaat 2500

 tc 2502

<210> 1448
<211> 699
<212> PRT
<213> Homo sapien

<400> 1448
 Met Ala Asp Ala Gly Ile Arg Arg Val Val Pro Ser Asp Leu Tyr
   1               5                  10                  15

 Pro Leu Val Leu Gly Phe Leu Arg Asp Asn Gln Leu Ser Glu Val
                  20                  25                  30

 Ala Asn Lys Phe Ala Lys Ala Thr Gly Ala Thr Gln Gln Asp Ala
                  35                  40                  45

 Asn Ala Ser Ser Leu Leu Asp Ile Tyr Ser Phe Trp Leu Lys Ser
                  50                  55                  60

 Ala Lys Val Pro Glu Arg Lys Leu Gln Ala Asn Gly Pro Val Ala
                  65                  70                  75

 Lys Lys Ala Lys Lys Lys Ala Ser Ser Ser Asp Ser Glu Asp Ser
                  80                  85                  90

 Ser Glu Glu Glu Glu Glu Val Gln Gly Pro Pro Ala Lys Lys Ala
                  95                 100                 105

 Ala Val Pro Ala Lys Arg Val Gly Leu Pro Pro Gly Lys Ala Ala
                 110                 115                 120

 Ala Lys Ala Ser Glu Ser Ser Ser Ser Glu Glu Ser Arg Asp Asp
                 125                 130                 135

 Asp Asp Glu Glu Asp Gln Lys Lys Gln Pro Val Gln Lys Gly Val
                 140                 145                 150

 Lys Pro Gln Ala Lys Ala Ala Lys Ala Pro Pro Lys Lys Ala Lys
                 155                 160                 165

 Ser Ser Asp Ser Asp Ser Asp Ser Ser Ser Glu Asp Glu Pro Pro
                 170                 175                 180

 Lys Asn Gln Lys Pro Lys Ile Thr Pro Val Thr Val Lys Ala Gln
                 185                 190                 195

 Thr Lys Ala Pro Pro Lys Pro Ala Arg Ala Ala Pro Lys Ile Ala
                 200                 205                 210

 Asn Gly Lys Ala Ala Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser
                 215                 220                 225

 Ser Ser Asp Asp Ser Glu Glu Glu Lys Ala Ala Ala Thr Pro Lys
                 230                 235                 240

 Lys Thr Val Pro Lys Lys Gln Val Val Ala Lys Ala Pro Val Lys
                 245                 250                 255

 Ala Ala Thr Thr Pro Thr Arg Lys Ser Ser Ser Ser Glu Asp Ser
                 260                 265                 270

 Ser Ser Asp Glu Glu Glu Glu Gln Lys Lys Pro Met Lys Asn Lys
                 275                 280                 285

 Pro Gly Pro Tyr Ser Tyr Ala Pro Pro Pro Ser Ala Pro Pro Pro
                 290                 295                 300

 Lys Lys Ser Leu Gly Thr Gln Pro Pro Lys Lys Ala Val Glu Lys
                 305                 310                 315

 Gln Gln Pro Val Glu Ser Ser Glu Asp Ser Ser Asp Glu Ser Asp
                 320                 325                 330

 Ser Ser Ser Glu Glu Glu Lys Lys Pro Pro Thr Lys Ala Val Val
                 335                 340                 345

 Ser Lys Ala Thr Thr Lys Pro Pro Pro Ala Lys Lys Ala Ala Glu
                 350                 355                 360

 Ser Ser Ser Asp Ser Ser Asp Ser Asp Ser Ser Glu Asp Asp Glu
                 365                 370                 375

 Ala Pro Ser Lys Pro Ala Gly Thr Thr Lys Asn Ser Ser Asn Lys
                 380                 385                 390

 Pro Ala Val Thr Thr Lys Ser Pro Ala Val Lys Pro Ala Ala Ala
                 395                 400                 405

 Pro Lys Gln Pro Val Gly Gly Gly Gln Lys Leu Leu Thr Arg Lys
                 410                 415                 420

 Ala Asp Ser Ser Ser Ser Glu Glu Glu Ser Ser Ser Ser Glu Glu
                 425                 430                 435

 Glu Lys Thr Lys Lys Met Val Ala Thr Thr Lys Pro Lys Ala Thr
                 440                 445                 450

 Ala Lys Ala Ala Leu Ser Leu Pro Ala Lys Gln Ala Pro Gln Gly
                 455                 460                 465

 Ser Arg Asp Ser Ser Ser Asp Ser Asp Ser Ser Ser Ser Glu Glu
                 470                 475                 480

 Glu Glu Glu Lys Thr Ser Lys Ser Ala Val Lys Lys Lys Pro Gln
                 485                 490                 495

 Lys Val Ala Gly Gly Ala Ala Pro Ser Lys Pro Ala Ser Ala Lys
                 500                 505                 510

 Lys Gly Lys Ala Glu Ser Ser Asn Ser Ser Ser Ser Asp Asp Ser
                 515                 520                 525

 Ser Glu Glu Glu Glu Glu Lys Leu Lys Gly Lys Gly Ser Pro Arg
                 530                 535                 540

 Pro Gln Ala Pro Lys Ala Asn Gly Thr Ser Ala Leu Thr Ala Gln
                 545                 550                 555

 Asn Gly Lys Ala Ala Lys Asn Ser Glu Glu Glu Glu Glu Glu Lys
                 560                 565                 570

 Lys Lys Ala Ala Val Val Val Ser Lys Ser Gly Ser Leu Lys Lys
                 575                 580                 585

 Arg Lys Gln Asn Glu Ala Ala Lys Glu Ala Glu Thr Pro Gln Ala
                 590                 595                 600

 Lys Lys Ile Lys Leu Gln Thr Pro Asn Thr Phe Pro Lys Arg Lys
                 605                 610                 615

 Lys Gly Glu Lys Arg Ala Ser Ser Pro Phe Arg Arg Val Arg Glu
                 620                 625                 630

 Glu Glu Ile Glu Val Asp Ser Arg Val Ala Asp Asn Ser Phe Asp
                 635                 640                 645

 Ala Lys Arg Gly Ala Ala Gly Asp Trp Gly Glu Arg Ala Asn Gln
                 650                 655                 660

 Val Leu Lys Phe Thr Lys Gly Lys Ser Phe Arg His Glu Lys Thr
                 665                 670                 675

 Lys Lys Lys Arg Gly Ser Tyr Arg Gly Gly Ser Ile Ser Val Gln
                 680                 685                 690

 Val Asn Ser Ile Lys Phe Asp Ser Glu
                 695

<210> 1449
<211> 3100
<212> DNA
<213> Homo sapien

<400> 1449
 actcgtctct ggtaaagtct gagcaggaca gggtggctga ctggcagatc 50

 cagaggttcc cttggcagtc cacgccaggc cttcaccatg gatcagttcc 100

 ctgaatcagt gacagaaaac tttgagtacg atgatttggc tgaggcctgt 150

 tatattgggg acatcgtggt ctttgggact gtgttcctgt ccatattcta 200

 ctccgtcatc tttgccattg gcctggtggg aaatttgttg gtagtgtttg 250

 ccctcaccaa cagcaagaag cccaagagtg tcaccgacat ttacctcctg 300

 aacctggcct tgtctgatct gctgtttgta gccactttgc ccttctggac 350

 tcactatttg ataaatgaaa agggcctcca caatgccatg tgcaaattca 400

 ctaccgcctt cttcttcatc ggcttttttg gaagcatatt cttcatcacc 450

 gtcatcagca ttgataggta cctggccatc gtcctggccg ccaactccat 500

 gaacaaccgg accgtgcagc atggcgtcac catcagccta ggcgtctggg 550

 cagcagccat tttggtggca gcaccccagt tcatgttcac aaagcagaaa 600

 gaaaatgaat gccttggtga ctaccccgag gtcctccagg aaatctggcc 650

 cgtgctccgc aatgtggaaa caaattttct tggcttccta ctccccctgc 700

 tcattatgag ttattgctac ttcagaatca tccagacgct gttttcctgc 750

 aagaaccaca agaaagccaa agccattaaa ctgatccttc tggtggtcat 800

 cgtgtttttc ctcttctgga caccctacaa cgttatgatt ttcctggaga 850

 cgcttaagct ctatgacttc tttcccagtt gtgacatgag gaaggatctg 900

 aggctggccc tcagtgtgac tgagacggtt gcatttagcc attgttgcct 950

 gaatcctctc atctatgcat ttgctgggga gaagttcaga agataccttt 1000

 accacctgta tgggaaatgc ctggctgtcc tgtgtgggcg ctcagtccac 1050

 gttgatttct cctcatctga atcacaaagg agcaggcatg gaagtgttct 1100

 gagcagcaat tttacttacc acacgagtga tggagatgca ttgctccttc 1150

 tctgaaggga atcccaaagc cttgtgtcta cagagaacct ggagttcctg 1200

 aacctgatgc tgactagtga ggaaagattt ttgttgttat ttcttacagg 1250

 cacaaaatga tggacccaat gcacacaaaa caaccctaga gtgttgttga 1300

 gaattgtgct caaaatttga agaatgaaca aattgaactc tttgaatgac 1350

 aaagagtaga catttctctt actgcaaatg tcatcagaac tttttggttt 1400

 gcagatgaca aaaattcaac tcagactagt ttagttaaat gagggtggtg 1450

 aatattgttc atattgtggc acaagcaaaa gggtgtctga gccctcaaag 1500

 tgaggggaaa ccagggcctg agccaagcta gaattccctc tctctgactc 1550

 tcaaatcttt tagtcattat agatccccca gactttacat gacacagctt 1600

 tatcaccaga gagggactga cacccatgtt tctctggccc caagggaaaa 1650

 ttcccaggga agtgctctga taggccaagt ttgtatcagg tgcccatccc 1700

 tggaaggtgc tgttatccat ggggaaggga tatataagat ggaagcttcc 1750

 agtccaatct catggagaag cagaaataca tatttccaag aagttggatg 1800

 ggtgggtact attctgatta cacaaaacaa atgccacaca tcacccttac 1850

 catgtgcctg atccagcctc tcccctgatt acaccagcct cgtcttcatt 1900

 aagccctctt ccatcatgtc cccaaacctg caagggctcc ccactgccta 1950

 ctgcatcgag tcaaaactca aatgcttggc ttctcatacg tccaccatgg 2000

 ggtcctacca atagattccc cattgcctcc tccttcccaa aggactccac 2050

 ccatcctatc agcctgtctc ttccatatga cctcatgcat ctccacctgc 2100

 tcccaggcca gtaagggaaa tagaaaaacc ctgcccccaa ataagaaggg 2150

 atggattcca accccaactc cagtagcttg ggacaaatca agcttcagtt 2200

 tcctggtctg tagaagaggg ataaggtacc tttcacatag agatcatcct 2250

 ttccagcatg aggaactagc caccaactct tgcaggtctc aacccttttg 2300

 tctgcctctt agacttctgc tttccacacc tgcactgctg tgctgtgccc 2350

 aagttgtggt gctgacaaag cttggaagag cctgcaggtg ccttggccgc 2400

 gtgcatagcc cagacacaga agaggctggt tcttacgatg gcacccagtg 2450

 agcactccca agtctacaga gtgatagcct tccgtaaccc aactctcctg 2500

 gactgccttg aatatcccct cccagtcacc ttgtgcaagc ccctgcccat 2550

 ctgggaaaat accccatcat tcatgctact gccaacctgg ggagccaggg 2600

 ctatgggagc agcttttttt tcccccctag aaacgtttgg aacaatgtaa 2650

 aactttaaag ctcgaaaaca attgtaataa tgctaaagaa aaagtcatcc 2700

 aatctaacca catcaatatt gtcattcctg tattcacccg tccagacctt 2750

 gttcacactc tcacatgttt agagttgcaa tcgtaatgta cagatggttt 2800

 tataatctga tttgttttcc tcttaacgtt agaccacaaa tagtgctcgc 2850

 tttctatgta gtttggtaat tatcatttta gaagactcta ccagactgtg 2900

 tattcattga agtcagatgt ggtaactgtt aaattgctgt gtatctgata 2950

 gctctttggc agtctatatg tttgtataat gaatgagaga ataagtcatg 3000

 ttccttcaag atcatgtacc ccaatttact tgccattact caattgataa 3050

 acatttaact tgtttccaat gtttagcaaa tacatatttt atagaacttc 3100

<210> 1450
<211> 355
<212> PRT
<213> Homo sapien

<400> 1450
 Met Asp Gln Phe Pro Glu Ser Val Thr Glu Asn Phe Glu Tyr Asp
   1               5                  10                  15

 Asp Leu Ala Glu Ala Cys Tyr Ile Gly Asp Ile Val Val Phe Gly
                  20                  25                  30

 Thr Val Phe Leu Ser Ile Phe Tyr Ser Val Ile Phe Ala Ile Gly
                  35                  40                  45

 Leu Val Gly Asn Leu Leu Val Val Phe Ala Leu Thr Asn Ser Lys
                  50                  55                  60

 Lys Pro Lys Ser Val Thr Asp Ile Tyr Leu Leu Asn Leu Ala Leu
                  65                  70                  75

 Ser Asp Leu Leu Phe Val Ala Thr Leu Pro Phe Trp Thr His Tyr
                  80                  85                  90

 Leu Ile Asn Glu Lys Gly Leu His Asn Ala Met Cys Lys Phe Thr
                  95                 100                 105

 Thr Ala Phe Phe Phe Ile Gly Phe Phe Gly Ser Ile Phe Phe Ile
                 110                 115                 120

 Thr Val Ile Ser Ile Asp Arg Tyr Leu Ala Ile Val Leu Ala Ala
                 125                 130                 135

 Asn Ser Met Asn Asn Arg Thr Val Gln His Gly Val Thr Ile Ser
                 140                 145                 150

 Leu Gly Val Trp Ala Ala Ala Ile Leu Val Ala Ala Pro Gln Phe
                 155                 160                 165

 Met Phe Thr Lys Gln Lys Glu Asn Glu Cys Leu Gly Asp Tyr Pro
                 170                 175                 180

 Glu Val Leu Gln Glu Ile Trp Pro Val Leu Arg Asn Val Glu Thr
                 185                 190                 195

 Asn Phe Leu Gly Phe Leu Leu Pro Leu Leu Ile Met Ser Tyr Cys
                 200                 205                 210

 Tyr Phe Arg Ile Ile Gln Thr Leu Phe Ser Cys Lys Asn His Lys
                 215                 220                 225

 Lys Ala Lys Ala Ile Lys Leu Ile Leu Leu Val Val Ile Val Phe
                 230                 235                 240

 Phe Leu Phe Trp Thr Pro Tyr Asn Val Met Ile Phe Leu Glu Thr
                 245                 250                 255

 Leu Lys Leu Tyr Asp Phe Phe Pro Ser Cys Asp Met Arg Lys Asp
                 260                 265                 270

 Leu Arg Leu Ala Leu Ser Val Thr Glu Thr Val Ala Phe Ser His
                 275                 280                 285

 Cys Cys Leu Asn Pro Leu Ile Tyr Ala Phe Ala Gly Glu Lys Phe
                 290                 295                 300

 Arg Arg Tyr Leu Tyr His Leu Tyr Gly Lys Cys Leu Ala Val Leu
                 305                 310                 315

 Cys Gly Arg Ser Val His Val Asp Phe Ser Ser Ser Glu Ser Gln
                 320                 325                 330

 Arg Ser Arg His Gly Ser Val Leu Ser Ser Asn Phe Thr Tyr His
                 335                 340                 345

 Thr Ser Asp Gly Asp Ala Leu Leu Leu Leu
                 350                 355

<210> 1451
<211> 1365
<212> DNA
<213> Homo sapien

<400> 1451
 cactgcttga gccgctgaga gggtggcgac gtcggggcca tggggctggg 50

 cccggtcttc ctgcttctgg ctggcatctt cccttttgca cctccgggag 100

 ctgctgctga gccccacagt cttcgttata acctcacggt gctgtcctgg 150

 gatggatctg tgcagtcagg gtttctcact gaggtacatc tggatggtca 200

 gcccttcctg cgctgtgaca ggcagaaatg cagggcaaag ccccagggac 250

 agtgggcaga agatgtcctg ggaaataaga catgggacag agagaccaga 300

 gacttgacag ggaacggaaa ggacctcagg atgaccctgg ctcatatcaa 350

 ggaccagaaa gaaggcttgc attccctcca ggagattagg gtctgtgaga 400

 tccatgaaga caacagcacc aggagctccc agcatttcta ctacgatggg 450

 gagctcttcc tctcccaaaa cctggagact aaggaatgga caatgcccca 500

 gtcctccaga gctcagacct tggccatgaa cgtcaggaat ttcttgaagg 550

 aagatgccat gaagaccaag acacactatc acgctatgca tgcagactgc 600

 ctgcaggaac tacggcgata tctaaaatcc ggcgtagtcc tgaggagaac 650

 agtgcccccc atggtgaatg tcacccgcag cgaggcctca gagggcaaca 700

 ttaccgtgac atgcagggct tctggcttct atccctggaa tatcacactg 750

 agctggcgtc aggatggggt atctttgagc cacgacaccc agcagtgggg 800

 ggatgtcctg cctgatggga atggaaccta ccagacctgg gtggccacca 850

 ggatttgcca aggagaggag cagaggttca cctgctacat ggaacacagc 900

 gggaatcaca gcactcaccc tgtgccctct gggaaagtgc tggtgcttca 950

 gagtcattgg cagacattcc atgtttctgc tgttgctgct gctgctattt 1000

 ttgttattat tattttctat gtccgttgtt gtaagaagaa aacatcagct 1050

 gcagagggtc cagagctcgt gagcctgcag gtcctggatc aacacccagt 1100

 tgggacgagt gaccacaggg atgccacaca gctcggattt cagcctctga 1150

 tgtcagatct tgggtccact ggctccactg agggcgccta gactctacag 1200

 ccaggcagct gggattcaat tccctgcctg gatctcacga gcactttccc 1250

 tcttggtgcc tcagtttcct gacctatgaa acagagaaaa taaaagcact 1300

 tatttattgt tgttggaggc tgcaaaatgt tagtagatat gaggcgtttg 1350

 cagctgtacc atatt 1365

<210> 1452
<211> 383
<212> PRT
<213> Homo sapien

<400> 1452
 Met Gly Leu Gly Pro Val Phe Leu Leu Leu Ala Gly Ile Phe Pro
   1               5                  10                  15

 Phe Ala Pro Pro Gly Ala Ala Ala Glu Pro His Ser Leu Arg Tyr
                  20                  25                  30

 Asn Leu Thr Val Leu Ser Trp Asp Gly Ser Val Gln Ser Gly Phe
                  35                  40                  45

 Leu Thr Glu Val His Leu Asp Gly Gln Pro Phe Leu Arg Cys Asp
                  50                  55                  60

 Arg Gln Lys Cys Arg Ala Lys Pro Gln Gly Gln Trp Ala Glu Asp
                  65                  70                  75

 Val Leu Gly Asn Lys Thr Trp Asp Arg Glu Thr Arg Asp Leu Thr
                  80                  85                  90

 Gly Asn Gly Lys Asp Leu Arg Met Thr Leu Ala His Ile Lys Asp
                  95                 100                 105

 Gln Lys Glu Gly Leu His Ser Leu Gln Glu Ile Arg Val Cys Glu
                 110                 115                 120

 Ile His Glu Asp Asn Ser Thr Arg Ser Ser Gln His Phe Tyr Tyr
                 125                 130                 135

 Asp Gly Glu Leu Phe Leu Ser Gln Asn Leu Glu Thr Lys Glu Trp
                 140                 145                 150

 Thr Met Pro Gln Ser Ser Arg Ala Gln Thr Leu Ala Met Asn Val
                 155                 160                 165

 Arg Asn Phe Leu Lys Glu Asp Ala Met Lys Thr Lys Thr His Tyr
                 170                 175                 180

 His Ala Met His Ala Asp Cys Leu Gln Glu Leu Arg Arg Tyr Leu
                 185                 190                 195

 Lys Ser Gly Val Val Leu Arg Arg Thr Val Pro Pro Met Val Asn
                 200                 205                 210

 Val Thr Arg Ser Glu Ala Ser Glu Gly Asn Ile Thr Val Thr Cys
                 215                 220                 225

 Arg Ala Ser Gly Phe Tyr Pro Trp Asn Ile Thr Leu Ser Trp Arg
                 230                 235                 240

 Gln Asp Gly Val Ser Leu Ser His Asp Thr Gln Gln Trp Gly Asp
                 245                 250                 255

 Val Leu Pro Asp Gly Asn Gly Thr Tyr Gln Thr Trp Val Ala Thr
                 260                 265                 270

 Arg Ile Cys Gln Gly Glu Glu Gln Arg Phe Thr Cys Tyr Met Glu
                 275                 280                 285

 His Ser Gly Asn His Ser Thr His Pro Val Pro Ser Gly Lys Val
                 290                 295                 300

 Leu Val Leu Gln Ser His Trp Gln Thr Phe His Val Ser Ala Val
                 305                 310                 315

 Ala Ala Ala Ala Ile Phe Val Ile Ile Ile Phe Tyr Val Arg Cys
                 320                 325                 330

 Cys Lys Lys Lys Thr Ser Ala Ala Glu Gly Pro Glu Leu Val Ser
                 335                 340                 345

 Leu Gln Val Leu Asp Gln His Pro Val Gly Thr Ser Asp His Arg
                 350                 355                 360

 Asp Ala Thr Gln Leu Gly Phe Gln Pro Leu Met Ser Asp Leu Gly
                 365                 370                 375

 Ser Thr Gly Ser Thr Glu Gly Ala
                 380

<210> 1453
<211> 6530
<212> DNA
<213> Homo sapien

<400> 1453
 gtcggggccg ctttgcaggt ccctagtcag gaccgagcag gggagtagga 50

 taggaatccc cgccgcacct ttgtacgagc ctgacccctt ccgtgggttt 100

 gttcctgggt cgccgtcaag ctgcggtctc tcctcccccg cccttcagcc 150

 ccgcggtctc caggggcggc gccctgggtc tggaacgcgg ttgccaccga 200

 ggaggcggcg gccctgcgtc tggaacgccg ttgccaccga ggaggcggcg 250

 gccccgagcg cgcctggaag ccccgggcaa ccggccaggg tcgggcacag 300

 gtggggtccg tcaggccgcc cggggctcct ctgtcccagc tctgcggccc 350

 agggggtgac gtgatggcgg cagcggtgct gacggaccgg gcccaggtgt 400

 ctgtgacctt tgatgatgtg gctgtgactt tcaccaagga ggagtggggg 450

 cagctggacc tagctcagcg gaccctgtac caggaggtga tgctggaaaa 500

 ctgtgggctc ctggtgtctc tggggtgtcc tgttcccaaa gctgagctga 550

 tctgccacct agagcatggg caggagccat ggaccaggaa ggaagacctc 600

 tcccaagaca cctgtccagg cgacaaagga aaacctaaga ccacagaacc 650

 taccacttgt gagccagcct tgtcagaggg aatctcactt cagggacaag 700

 tgacacaagg aaactcagtg gactcacagt tggggcaagc cgaggatcag 750

 gatgggctat cagaaatgca ggaaggacac ttcagaccag gaatagatcc 800

 ccaggagaag tctcctggga agatgagccc tgaatgtgat ggtttaggga 850

 cagctgatgg tgtgtgttca aggattggac aggagcaagt ctctccagga 900

 gatagagtcc gtagccataa ctcatgtgag tcaggtaaag atcccatgat 950

 tcaggaagag gaaaataact ttaaatgcag tgaatgtgga aaagtattta 1000

 acaagaaaca cctccttgct ggacatgaga aaattcactc tggagttaag 1050

 ccctatgaat gcacagaatg tgggaaaacc tttattaaga gcacacatct 1100

 cctgcaacat cacatgatcc acactgggga gaggccctat gagtgcatgg 1150

 agtgtggaaa ggccttcaac cgcaagtcat accttaccca gcaccagcgg 1200

 attcacagtg gagagaagcc ttacaagtgc aatgaatgcg gaaaggcctt 1250

 cacccaccgc tccaattttg tcttgcataa caggagacac actggagaaa 1300

 aatcctttgt gtgcacagaa tgtggccaag tctttcgaca taggccaggc 1350

 tttctccggc actatgttgt ccacagtggt gagaatccct atgagtgctt 1400

 ggagtgtggc aaggtcttca aacacaggtc atatctcatg tggcaccagc 1450

 agactcatac cggggagaag ccctatgagt gcagtgaatg tgggaaggtc 1500

 ttcttggaga gtgcagccct gattcaccac tatgtcatcc acactggaga 1550

 gaagcccttt gagtgcctcg agtgtgggaa ggctttcaac caccgatcct 1600

 acctcaagag gcaccagcgg attcacactg gggagaagcc cttcgtgtgc 1650

 agtgaatgtg gaaaggcctt cacccactgc tctactttta tcttgcataa 1700

 aagggcccac actggagaaa agcctttcga gtgcaaagag tgtgggaaag 1750

 cctttagcaa tcggaaggac ctcattcgcc acttcagcat ccacactgga 1800

 gagaagccct atgagtgcgt ggagtgtgga aaggccttca cccgcatgtc 1850

 gggcctcacg aggcacaagc ggattcatag tggagagaag ccctatgaat 1900

 gtgttgagtg tgggaaatcg ttttgctgga gcacaaacct cattcgacat 1950

 gccattatcc acactggaga gaagccctat aaatgtagtg aatgtggaaa 2000

 ggccttcagt cgcagctcgt ccctcactca gcatcaaagg atgcatactg 2050

 ggaaaaatcc catcagtgta acagatgtgg gaagaccttt tacaagtgga 2100

 caaacctcag ttacccttcg agaacttctt ttagggaagg actttttgaa 2150

 tgtaaccact gaggcaaata ttttgccaga ggaaacatct tcctctgcat 2200

 ctgatcaacc ataccaaaga gaaaccccac aagtgtcttc actgtgagaa 2250

 aaccttctgt tgctgaatat tacttgtcat ctgaagagtc atattagaaa 2300

 ttcgttcagt ctagagcctt attctccatc tgataattta tcctggagag 2350

 agacccagtg gttattgtgc acataggaga accttcagct gcatctttct 2400

 ccttagttta cagtgcaatt ttatctcagg aattattttt aaaaggagga 2450

 ggggacatag aaaaaatgaa atgcaagcac acatcttttc aggcttctct 2500

 gccaagccta tggcgctttg tcatggattt cttagtgtat ttgggggaag 2550

 ggaaatgttt caaggtaaag aaccttgacc ctttatgtgc ttgtatgtac 2600

 atttattgct atccagtgtc agaacagtta gtttaggaaa agtatgcaaa 2650

 ctttaatcgc acatcttctg tattccacaa tagtacttac tcttgagaag 2700

 cataacttta tgacaactta gggggcttga gccatgaaat actcacgttt 2750

 aagtcagtaa ggatacacat gttaacattc aggcttttgt cttgatgccc 2800

 gtcttttggt ttacgtcatc attgtagcca tatggtaaat ttttatttgt 2850

 taaattttta aaaattactt agctcaaaat gtcagtggta aatttttaaa 2900

 ttgagtaaag tgattcttct ttgctcttat ttaaaatcga cagcatttct 2950

 agttcctttg acattccata taatttttag gattagtttg tacttattta 3000

 caaaacagtc ttgttcagat ttttacagaa attgagttaa gtctgtggat 3050

 taatctgtta agaattggta tctttactat gttgggtctt gtagttcatg 3100

 agtgcaggag taggcctctt aatttataat agttaagcat tccttaaagt 3150

 atttcattaa tgttaaaaat tttcagcgta tagatcccta tgcatttttg 3200

 ttagaatttg catcctaggg tgcttttttg tttgtgtgtg tgtgtaattt 3250

 gagtgattgt aaatggcatt gatgtttgaa ctttgaattg cacacaattt 3300

 ttggtagtat acagaaatat aatatttttg gacattgttt tgctaccctg 3350

 caaccttatt gagttcactt attattttta gctatttctt tcgacagaat 3400

 ccttggaatt ttctatatag aaatgtcatc tgcaaataca gaccattttt 3450

 tatctttcat cttacctgta atcctagcac tttgagacca ctaaggcggg 3500

 tggatcacct gaggccagga gttcgagacc agcctggcca acatggcaaa 3550

 accctgtcta ctaaaaatac aaaaattagc cgggcatggt ggcgtgtgcc 3600

 tgtggtccca gctgctgggg ggctgaggca ggaggatcag ttgaacgtgg 3650

 gaggcggagg ttgcagtgag ctgagatctc accactgcac tccagcctgg 3700

 gcagcagagc gagactctgt ctcaacaaca acaacaaaaa gtcctgaaca 3750

 tgattgtgga agtgtgttgc tctttcaagt tctatcactt tttgtttgca 3800

 aagttcaaag ctgtattgtt tggtacatat acatgtaggt ttgccaagtc 3850

 tttgtggtga attgactctt ctgtcattat gtgatgtcat ttttttgcct 3900

 tttaatagtc ttgtcaatac tttacctgat gttctcatag tgactcctgc 3950

 atattttgat taatgtttgc atggttaata tttcttcatt ttattttaaa 4000

 gcttacctgt atcattactt atgaagtcag tttctttgaa cagcatatac 4050

 tcaggccatg ctttttttat tcattctgca tatgtctctc ttaattggta 4100

 tgttgaaatg atttacatta aaataattat tgatatttta gggcttaagt 4150

 gtgcccttaa atgatttttg tgttcttttt tattgttcct ctgttatttg 4200

 gggttgttta ctagtcttcc tataggttac ttcacctttt ttttttttaa 4250

 taatttgatt tgatacatat gtagtgtttt ttagtataga tcctccttga 4300

 cttatgatgg ggttatgtca caataaaccc attgcaagtt gaaaatacta 4350

 tgtcaaatat gcatttaata cacctaccct gctgaacatc atagccgatc 4400

 ttgccttcag aatgctcaga aaatttacat tagcctgcag ttgggcaaaa 4450

 tcatctaaca caaggcctac tttataataa agttactgca aagaatttta 4500

 aataaaaatt caagtgtggt ttctactgaa tgcatgtcgc attcgcacca 4550

 ttgtaaagtc aagtagtaag tcgaaccatc ctaagtcagg gactgtctgt 4600

 atatatctgc attttttagt gattgttcta ctattacagt gtaaatatat 4650

 aacttatgac agtttaataa gttatcagca atttagcact ttacttccat 4700

 taggttcctt tagcttacct actaatgtaa ctatcttaag taatagtaat 4750

 tcctcttcaa aaattgagcg ctatgttgca agatgtaatt tttcttttcc 4800

 ttttttttga gaccaagtct cactctgtca cccacgctgg agtgctgtga 4850

 tgcgatctcg gctctctgca acctctgcct cccgggttca agcaattaac 4900

 tgcctcagct tccctagtaa tggattacag gcgcccgcca ccacgcctgg 4950

 ctaatttttg tatttttagt agagacgggg tttcaccatc ttggccaggt 5000

 tggtcttgaa ctcttgacct catgatccac ccgcctcggc cccccaaagt 5050

 gctggggtta caggtgtgag ccactgcacc cggccacaag atgtaatttt 5100

 tactttatct ctcacacgta ttttacaaaa cgtcatgaga aacattgtct 5150

 cttgaccttt tttttttttt ttttttttta aagagacaga gtctcactct 5200

 gtcacccagg ctggagtgca gtggcacgat cttggctcac tgcaacctcc 5250

 gcctcctggg ttcaagcgat tctcctgcct cagcctcctg agtagctggg 5300

 attacaggtg tgcgccgcca cacccagcta attttgtatt tttagtagag 5350

 acggggtttc accatgttgc tcaggctggt ctcaaactcc tgaccttgtg 5400

 atccgccaac cttggcctgt cgacctcttt acccattcca ttgttcattc 5450

 ttctttcttg aaatcccaaa ccttctatta acatttcttt tcagttatac 5500

 actgaacttt actgtagcct ttcttctaga gtaacaaatg ttctttgttt 5550

 tccttcctct aaagatgtct ttatgtttcc ttcattccca aagaatattt 5600

 ttgtggaata taagattcag agttggcagt tgttttcttt tagacttcag 5650

 agatgtatct ctctgttctg tacattattg tttaatataa gaaacctact 5700

 accattcaaa taatcattcc ctattttaca atgcatcagt tctgtcaagc 5750

 ttcattcaaa gtgtttttca ttgtctctag tgttcagaag tttggctgtg 5800

 atgtgcgtgg catggaagtt tttgggtgta ttctatttgg cgctccctgg 5850

 tgcttgccca gctttttgat ctgtaggatt atgccttttg caaaatttgg 5900

 ggaactttca actattattt cttcaaatat tttttcaccc cccagtcttg 5950

 tcttttttag ggacttcaat aacatgagtg gcagatcttg ttttacactc 6000

 ccatgggtcc ttcaggctct catctttttt ctttttccag tctattttct 6050

 gtcttgttaa tattgattaa tttttattga ccttccatgg tcctcactga 6100

 ttgttttctt tgtcatacct aatctgttga gtttgtgcag tgagttttca 6150

 ttttggtttt gtattttcca gttgtttaat ttccattggg tgggttcttt 6200

 tgtacacctt ctgtttcttt gcttattttt taacgccaaa gaaagactct 6250

 cagagaatag acaactatat tccaaagtca tggttctctg gtggtttgtc 6300

 ttgacatttg aatagaaatg ttaaactatc tgggggaata gaaagcccac 6350

 agtcttctga gttgtgctac accaatattt ctatgaacag atcttacaac 6400

 tgagagtgat ctgcagattt ttcagagtca tgttctccat ggaatgtttg 6450

 taaaattccc tagctctctg cactgagctg agatcgtgcc actgcactcc 6500

 agcctgggca acagagcgag actccatctc 6530

<210> 1454
<211> 627
<212> PRT
<213> Homo sapien

<400> 1454
 Met Ala Ala Ala Val Leu Thr Asp Arg Ala Gln Val Ser Val Thr
   1               5                  10                  15

 Phe Asp Asp Val Ala Val Thr Phe Thr Lys Glu Glu Trp Gly Gln
                  20                  25                  30

 Leu Asp Leu Ala Gln Arg Thr Leu Tyr Gln Glu Val Met Leu Glu
                  35                  40                  45

 Asn Cys Gly Leu Leu Val Ser Leu Gly Cys Pro Val Pro Lys Ala
                  50                  55                  60

 Glu Leu Ile Cys His Leu Glu His Gly Gln Glu Pro Trp Thr Arg
                  65                  70                  75

 Lys Glu Asp Leu Ser Gln Asp Thr Cys Pro Gly Asp Lys Gly Lys
                  80                  85                  90

 Pro Lys Thr Thr Glu Pro Thr Thr Cys Glu Pro Ala Leu Ser Glu
                  95                 100                 105

 Gly Ile Ser Leu Gln Gly Gln Val Thr Gln Gly Asn Ser Val Asp
                 110                 115                 120

 Ser Gln Leu Gly Gln Ala Glu Asp Gln Asp Gly Leu Ser Glu Met
                 125                 130                 135

 Gln Glu Gly His Phe Arg Pro Gly Ile Asp Pro Gln Glu Lys Ser
                 140                 145                 150

 Pro Gly Lys Met Ser Pro Glu Cys Asp Gly Leu Gly Thr Ala Asp
                 155                 160                 165

 Gly Val Cys Ser Arg Ile Gly Gln Glu Gln Val Ser Pro Gly Asp
                 170                 175                 180

 Arg Val Arg Ser His Asn Ser Cys Glu Ser Gly Lys Asp Pro Met
                 185                 190                 195

 Ile Gln Glu Glu Glu Asn Asn Phe Lys Cys Ser Glu Cys Gly Lys
                 200                 205                 210

 Val Phe Asn Lys Lys His Leu Leu Ala Gly His Glu Lys Ile His
                 215                 220                 225

 Ser Gly Val Lys Pro Tyr Glu Cys Thr Glu Cys Gly Lys Thr Phe
                 230                 235                 240

 Ile Lys Ser Thr His Leu Leu Gln His His Met Ile His Thr Gly
                 245                 250                 255

 Glu Arg Pro Tyr Glu Cys Met Glu Cys Gly Lys Ala Phe Asn Arg
                 260                 265                 270

 Lys Ser Tyr Leu Thr Gln His Gln Arg Ile His Ser Gly Glu Lys
                 275                 280                 285

 Pro Tyr Lys Cys Asn Glu Cys Gly Lys Ala Phe Thr His Arg Ser
                 290                 295                 300

 Asn Phe Val Leu His Asn Arg Arg His Thr Gly Glu Lys Ser Phe
                 305                 310                 315

 Val Cys Thr Glu Cys Gly Gln Val Phe Arg His Arg Pro Gly Phe
                 320                 325                 330

 Leu Arg His Tyr Val Val His Ser Gly Glu Asn Pro Tyr Glu Cys
                 335                 340                 345

 Leu Glu Cys Gly Lys Val Phe Lys His Arg Ser Tyr Leu Met Trp
                 350                 355                 360

 His Gln Gln Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Ser Glu
                 365                 370                 375

 Cys Gly Lys Val Phe Leu Glu Ser Ala Ala Leu Ile His His Tyr
                 380                 385                 390

 Val Ile His Thr Gly Glu Lys Pro Phe Glu Cys Leu Glu Cys Gly
                 395                 400                 405

 Lys Ala Phe Asn His Arg Ser Tyr Leu Lys Arg His Gln Arg Ile
                 410                 415                 420

 His Thr Gly Glu Lys Pro Phe Val Cys Ser Glu Cys Gly Lys Ala
                 425                 430                 435

 Phe Thr His Cys Ser Thr Phe Ile Leu His Lys Arg Ala His Thr
                 440                 445                 450

 Gly Glu Lys Pro Phe Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser
                 455                 460                 465

 Asn Arg Lys Asp Leu Ile Arg His Phe Ser Ile His Thr Gly Glu
                 470                 475                 480

 Lys Pro Tyr Glu Cys Val Glu Cys Gly Lys Ala Phe Thr Arg Met
                 485                 490                 495

 Ser Gly Leu Thr Arg His Lys Arg Ile His Ser Gly Glu Lys Pro
                 500                 505                 510

 Tyr Glu Cys Val Glu Cys Gly Lys Ser Phe Cys Trp Ser Thr Asn
                 515                 520                 525

 Leu Ile Arg His Ala Ile Ile His Thr Gly Glu Lys Pro Tyr Lys
                 530                 535                 540

 Cys Ser Glu Cys Gly Lys Ala Phe Ser Arg Ser Ser Ser Leu Thr
                 545                 550                 555

 Gln His Gln Arg Met His Thr Gly Lys Asn Pro Ile Ser Val Thr
                 560                 565                 570

 Asp Val Gly Arg Pro Phe Thr Ser Gly Gln Thr Ser Val Thr Leu
                 575                 580                 585

 Arg Glu Leu Leu Leu Gly Lys Asp Phe Leu Asn Val Thr Thr Glu
                 590                 595                 600

 Ala Asn Ile Leu Pro Glu Glu Thr Ser Ser Ser Ala Ser Asp Gln
                 605                 610                 615

 Pro Tyr Gln Arg Glu Thr Pro Gln Val Ser Ser Leu
                 620                 625

<210> 1455
<211> 5744
<212> DNA
<213> Homo sapien

<400> 1455
 agcgcatgga gccagaggag gaggatgaac taggctcagg gcgggatgtg 50

 gattccaact ccaacgcgga cagtgagaaa tgggtggcag gagatggttt 100

 ggaagaacag gaattttcta tcaaggaggc aaacttcaca gagggaagtc 150

 tgaagctaaa gattcagacc acaaagcggg ctaagaaacc cccaaagaat 200

 ttggagaact atatatgtcc acctgagatc aagatcacca tcaagcagtc 250

 tggggaccag aaggtgtccc gtgctggaaa aaatagcaaa gccacgaagg 300

 aggaagaaag aagccactcc aaaaagaagc tcctcacagc cagtgacctt 350

 gcagccagtg acctcaaagg atttcagcca caggcttacg aaaggcccca 400

 gaaacattca actctccatt atgacacggg cctcccacag gacttcaccg 450

 gtgacacctt aaaaccaaag caccagcaaa aaagcagcag ccagaaccac 500

 atggactggt ccaccaactc tgacagcgga cccgtcactc agaattgctt 550

 catcagtcca gagtctggca gagaaactgc aagcaccagc aagatccccg 600

 ctcttgagcc cgtggcttcc tttgcaaagg cccagggtaa gaaaggcagt 650

 gcagggaaca cgtggagtca gttgtctaac aataacaaag atctgctctt 700

 gggaggtgtg gctccatccc caagcagcca cagctcacca gccccaccca 750

 gcagctctgc tgagtgcaac gggcttcagc ccttggtgga tcaagatgga 800

 ggaggtacaa aggagccccc agaaccacct acggtgggca gcaagaaaaa 850

 gtccagtaaa aaagatgtga taagtcagac cataccaaac ccagacctgg 900

 attgggtcaa gaatgcccag aaagcatttg acaatacaga agggaaaagg 950

 gaaggttatt ccgcagatag tgcccaagag gcatcaccag ccaggcagaa 1000

 cgtgagttct gccagtaatc ctgaaaatga ctcaagtcat gtccggatta 1050

 ctatccccat caaggcaccc tctctggatc caaccaacca taagaggaaa 1100

 aaaagacagt ccattaaagc ggtggtggaa aagatcatgc cagagaaagc 1150

 cttggcttct ggaatcacca tgagcagtga agtagttaac aggatacttt 1200

 ccaactctga ggggaataag aaggatcccc gtgtccctaa gttgagtaaa 1250

 atgatagaga atgagtcccc ctcagttggc cttgaaactg gtggaaatgc 1300

 tgagaaagtt atcccaggag gtgtgtctaa gccgcggaag ccacccatgg 1350

 tcatgacacc tccaacgtgc acagatcact ctccatccag aaagctgcca 1400

 gaaatccagc atccaaaatt tgctgcaaaa cgaaggtgga cttgcagcaa 1450

 accaaaacct agcaccatgc ttcgagaggc agttatggcc acctctgata 1500

 aactgatgct ggagcccccg tctgcatatc ccatcacccc atccagccct 1550

 ctctacacca acacagacag tcttactgtg atcactccag tcaaaaagaa 1600

 gcggggacga ccaaagaagc agcctttgct cacagtcgag acgattcatg 1650

 agggaacttc caccagcccc gtcagtccca tcagccgaga gtttcctggc 1700

 actaagaaaa gaaagcgacg acgcaattta gcgaagttgg cccagctagt 1750

 gccgggagag gacaaaccca tgagcgagat gaaatttcac aagaaagttg 1800

 gaaagctcgg cgtgttggat aagaagacca tcaaaactat caataagatg 1850

 aagacactca agaggaaaaa catcttgaat cagatcttgt cctgttccag 1900

 cagcgttgct ctgaaggcaa aagctccccc agagaccagc cctggggcag 1950

 cagccattga aagcaaactg ggcaagcaga ttaatgtcag caagagggga 2000

 accatctaca ttggcaagaa gcggggcagg aagccaagag cagagctgcc 2050

 acccccatcc gaagaaccca aaacagccat caagcacccc aggcctgttt 2100

 ctagccagcc ggatgttcca gccgtgcctt ccaactttca gtcacttgtg 2150

 gcgtcttcac cagcagctat gcacccactt tcaacacagt taggtgggtc 2200

 caatggcaac ctgagccctg ccagcactga aaccaatttt tcagagttga 2250

 aaactatgcc aaatctccag cccatcagtg ctcttccaac caaaacccaa 2300

 aagggaatac acagtggaac ctggaagctg tctccaccca gactgatggc 2350

 caactcccct tcacacctgt gcgagattgg ctccctaaag gaaatcacgc 2400

 tgtcccctgt gagcgagtcc cacagtgagg agacgatccc cagcgacagc 2450

 ggcattggga cagacaacaa cagcacttct gaccaagcgg agaagagctc 2500

 agaatcccga aggaggtact cttttgattt ctgctccctg gacaacccgg 2550

 aggccattcc gtccgacacc agcacaaaga accggcatgg ccaccggcaa 2600

 aagcatctca ttgtggacaa ctttctggcc cacgaaagcc tcaagaagcc 2650

 aaagcacaag aggaaacgga aaagcctgca aaaccgcgat gacctccagt 2700

 ttctggcaga cctggaggag ctaatcacca agttccaagt gttcagaatc 2750

 tcccaccgga gttacacctt ctaccacgag aatccatatc ccagcatttt 2800

 tcggattaat tttgatcact attacccggt gccatatatc cagtatgacc 2850

 cgttgctcta tcttcgtagg acttcagact tgaagtcaaa gaagaagcgt 2900

 ggtaggcctg caaaaaccaa tgacaccatg acaaaggtgc cttttttaca 2950

 agggttcagc taccctattc ccagtggaag ttactatgca ccctatggaa 3000

 tgccttacac atcaatgcct atgatgaacc ttggttatta cggtcagtac 3050

 ccagctcctt tgtacctatc gcacacgctt ggagcagctt ccccattcat 3100

 gaggccaaca gtgccaccac ctcagttcca cacaaactcc cacataaaga 3150

 tgtccggtgc agctaagcat aaagccaagc atggagtaca cctgcaggga 3200

 cctgttagca tgggccttgg tgacatgcag ccttctctga accctcccaa 3250

 ggtaggcagt gccagtctgt ccagtggtcg gctccataag aggaaacaca 3300

 aacacaagca taagcacaag gaagaccgga tcctagggac ccatgacaac 3350

 ctgagtggtc tttttgcagg caaagccaca ggcttctcca gccacatcct 3400

 gagcgagcgg ctgagtagcg cagacaaaga gctcccgctg gtgagtgaga 3450

 agaacaagca taaggagaaa cagaagcacc agcacagcga agccggccac 3500

 aaagcttcta agaacaactt tgaggtggac accctgtcta cactgtcact 3550

 ttccgacgcc cagcattgga cacaggccaa ggaaaaagga gacttgagca 3600

 gtgagcctgt ggactcatgc acgaaaagat actctggcag tggcggggat 3650

 ggtggcagca cgagatcgga gaacctggac gtgttcagtg aaatgaaccc 3700

 ttcgaatgac aagtgggaca gtgacgtgag tgggagtaaa aggaggagct 3750

 atgaaggctt tggaacgtac agggaaaagg acatccaagc cttcaagatg 3800

 aaccgcaagg agagaagttc ttatgactcc tccatgtctc cagggatgcc 3850

 aagtccccac ttaaaagtgg accagacagc agtgcatagt aagaacgaag 3900

 gctcagtgcc caccatgatg accaggaaga agccagccgc agttgacagt 3950

 gttacaattc caccagcccc agtgttatct ctccttgctg catctgcagc 4000

 aacgtcggat gcagtcggct cctccctgaa gaagaggttc aagcggcggg 4050

 agatcgaagc catccagtgc gaagtgcgga agatgtgcaa ctacaccaag 4100

 atcctgtcca ccaagaagaa cctggaccac gtgaacaaga tcctgaaggc 4150

 caagcggctg cagagacaat caaaaacagg caacaacttc gtgaagaaga 4200

 ggcgcgggcg tcccaggaag cagcccaccc agttcgatga ggactccaga 4250

 gaccaaatgc cggtgctgga aaaatgcatc gacctgccca gcaaaagagg 4300

 ccagaagccc agcctgagcc cgctggtgct ggagcccgcc gccagccaag 4350

 acaccatcat ggccaccatc gaggcggtca tccacatggc ccgggaggcg 4400

 ccgcccctgc ccccgccacc gccgccgccc ctgccgccac cgccgccacc 4450

 acccctgccc ccgccacccc ctctacccaa gaccccccga ggcggaaaga 4500

 ggaaacacaa accgcaggcc cccgctcagc ccccacagca gtcgcccccg 4550

 cagcagcccc ttccccagga agaggaggtg aaagccaaaa ggcagaggaa 4600

 gtcccgaggg agtgagagcg aggtccttcc ctagggcggg tctgggcgtc 4650

 tgcacctggg gcctagggaa ctgacacgtg ggaagcgcag tgagccgggg 4700

 cgggggcgga atcccccgct gcagggacac ccacgccctt ctctccagaa 4750

 gccgggcagg cagaatccgg ccagacgacg gggctgagcc atcaggagct 4800

 cttgggaaag caaagcaggg agacaccttc agaagaagct tgtctgagct 4850

 tcaccgcagc tcccaccacg cggcgcttca gtacggctgg atcctccgca 4900

 ggcgagcgga aggcccccag gaggagcagg ctggtggcac tctcctgacc 4950

 tcacgctgcc aaggtgcgcc ctcgactccc gatttcattt gctggccagg 5000

 aaaatcgaaa gggaaacacc ctcaattagg aaacattcca aggggagaaa 5050

 agctgcaaat tgctcaactg gcattgctgt aacccgttcc atttaattgg 5100

 tttttatttc ttttgatttt caagctctgc taagctttgg ggtaccaacg 5150

 tcatcttcag gtgacctgaa tctttccctt aaccgtacag tttctcgatg 5200

 gaattgtgtg atcagaaggt ggaattctag tgataggcga cctcagaccc 5250

 gcattcatgt tctgtgtgcc tcttctattg cacatacact gatttttagc 5300

 attgtctatt cctatttttc ctttgcccat tgtacttcca tatatctttt 5350

 cattaactta cttgctgcct tttttttttc ttggtacaca tttaaataaa 5400

 gtaatcctta acctgtgctg taaagttcac ccttggcatg ctgttccaag 5450

 aacctgggtt tgaatcccaa tcgttgtgaa acatactcag tattgataaa 5500

 acctttttaa taagtgatgc agagcagcca aggatatgtt gacccagatg 5550

 tcaaccaggc tatttttata cttaaaacat gtcagcagag cataggcaga 5600

 ataaaatggt ttaaataccc cacagcaaat agagtaactg acaaaccacc 5650

 aaaaactgaa accccagacc caccagaaag acaagtgtct agcaatgcct 5700

 tggtacctga tctttttcat tcaaataatt gtcataggtt gttc 5744

<210> 1456
<211> 1542
<212> PRT
<213> Homo sapien

<400> 1456
 Met Glu Pro Glu Glu Glu Asp Glu Leu Gly Ser Gly Arg Asp Val
   1               5                  10                  15

 Asp Ser Asn Ser Asn Ala Asp Ser Glu Lys Trp Val Ala Gly Asp
                  20                  25                  30

 Gly Leu Glu Glu Gln Glu Phe Ser Ile Lys Glu Ala Asn Phe Thr
                  35                  40                  45

 Glu Gly Ser Leu Lys Leu Lys Ile Gln Thr Thr Lys Arg Ala Lys
                  50                  55                  60

 Lys Pro Pro Lys Asn Leu Glu Asn Tyr Ile Cys Pro Pro Glu Ile
                  65                  70                  75

 Lys Ile Thr Ile Lys Gln Ser Gly Asp Gln Lys Val Ser Arg Ala
                  80                  85                  90

 Gly Lys Asn Ser Lys Ala Thr Lys Glu Glu Glu Arg Ser His Ser
                  95                 100                 105

 Lys Lys Lys Leu Leu Thr Ala Ser Asp Leu Ala Ala Ser Asp Leu
                 110                 115                 120

 Lys Gly Phe Gln Pro Gln Ala Tyr Glu Arg Pro Gln Lys His Ser
                 125                 130                 135

 Thr Leu His Tyr Asp Thr Gly Leu Pro Gln Asp Phe Thr Gly Asp
                 140                 145                 150

 Thr Leu Lys Pro Lys His Gln Gln Lys Ser Ser Ser Gln Asn His
                 155                 160                 165

 Met Asp Trp Ser Thr Asn Ser Asp Ser Gly Pro Val Thr Gln Asn
                 170                 175                 180

 Cys Phe Ile Ser Pro Glu Ser Gly Arg Glu Thr Ala Ser Thr Ser
                 185                 190                 195

 Lys Ile Pro Ala Leu Glu Pro Val Ala Ser Phe Ala Lys Ala Gln
                 200                 205                 210

 Gly Lys Lys Gly Ser Ala Gly Asn Thr Trp Ser Gln Leu Ser Asn
                 215                 220                 225

 Asn Asn Lys Asp Leu Leu Leu Gly Gly Val Ala Pro Ser Pro Ser
                 230                 235                 240

 Ser His Ser Ser Pro Ala Pro Pro Ser Ser Ser Ala Glu Cys Asn
                 245                 250                 255

 Gly Leu Gln Pro Leu Val Asp Gln Asp Gly Gly Gly Thr Lys Glu
                 260                 265                 270

 Pro Pro Glu Pro Pro Thr Val Gly Ser Lys Lys Lys Ser Ser Lys
                 275                 280                 285

 Lys Asp Val Ile Ser Gln Thr Ile Pro Asn Pro Asp Leu Asp Trp
                 290                 295                 300

 Val Lys Asn Ala Gln Lys Ala Phe Asp Asn Thr Glu Gly Lys Arg
                 305                 310                 315

 Glu Gly Tyr Ser Ala Asp Ser Ala Gln Glu Ala Ser Pro Ala Arg
                 320                 325                 330

 Gln Asn Val Ser Ser Ala Ser Asn Pro Glu Asn Asp Ser Ser His
                 335                 340                 345

 Val Arg Ile Thr Ile Pro Ile Lys Ala Pro Ser Leu Asp Pro Thr
                 350                 355                 360

 Asn His Lys Arg Lys Lys Arg Gln Ser Ile Lys Ala Val Val Glu
                 365                 370                 375

 Lys Ile Met Pro Glu Lys Ala Leu Ala Ser Gly Ile Thr Met Ser
                 380                 385                 390

 Ser Glu Val Val Asn Arg Ile Leu Ser Asn Ser Glu Gly Asn Lys
                 395                 400                 405

 Lys Asp Pro Arg Val Pro Lys Leu Ser Lys Met Ile Glu Asn Glu
                 410                 415                 420

 Ser Pro Ser Val Gly Leu Glu Thr Gly Gly Asn Ala Glu Lys Val
                 425                 430                 435

 Ile Pro Gly Gly Val Ser Lys Pro Arg Lys Pro Pro Met Val Met
                 440                 445                 450

 Thr Pro Pro Thr Cys Thr Asp His Ser Pro Ser Arg Lys Leu Pro
                 455                 460                 465

 Glu Ile Gln His Pro Lys Phe Ala Ala Lys Arg Arg Trp Thr Cys
                 470                 475                 480

 Ser Lys Pro Lys Pro Ser Thr Met Leu Arg Glu Ala Val Met Ala
                 485                 490                 495

 Thr Ser Asp Lys Leu Met Leu Glu Pro Pro Ser Ala Tyr Pro Ile
                 500                 505                 510

 Thr Pro Ser Ser Pro Leu Tyr Thr Asn Thr Asp Ser Leu Thr Val
                 515                 520                 525

 Ile Thr Pro Val Lys Lys Lys Arg Gly Arg Pro Lys Lys Gln Pro
                 530                 535                 540

 Leu Leu Thr Val Glu Thr Ile His Glu Gly Thr Ser Thr Ser Pro
                 545                 550                 555

 Val Ser Pro Ile Ser Arg Glu Phe Pro Gly Thr Lys Lys Arg Lys
                 560                 565                 570

 Arg Arg Arg Asn Leu Ala Lys Leu Ala Gln Leu Val Pro Gly Glu
                 575                 580                 585

 Asp Lys Pro Met Ser Glu Met Lys Phe His Lys Lys Val Gly Lys
                 590                 595                 600

 Leu Gly Val Leu Asp Lys Lys Thr Ile Lys Thr Ile Asn Lys Met
                 605                 610                 615

 Lys Thr Leu Lys Arg Lys Asn Ile Leu Asn Gln Ile Leu Ser Cys
                 620                 625                 630

 Ser Ser Ser Val Ala Leu Lys Ala Lys Ala Pro Pro Glu Thr Ser
                 635                 640                 645

 Pro Gly Ala Ala Ala Ile Glu Ser Lys Leu Gly Lys Gln Ile Asn
                 650                 655                 660

 Val Ser Lys Arg Gly Thr Ile Tyr Ile Gly Lys Lys Arg Gly Arg
                 665                 670                 675

 Lys Pro Arg Ala Glu Leu Pro Pro Pro Ser Glu Glu Pro Lys Thr
                 680                 685                 690

 Ala Ile Lys His Pro Arg Pro Val Ser Ser Gln Pro Asp Val Pro
                 695                 700                 705

 Ala Val Pro Ser Asn Phe Gln Ser Leu Val Ala Ser Ser Pro Ala
                 710                 715                 720

 Ala Met His Pro Leu Ser Thr Gln Leu Gly Gly Ser Asn Gly Asn
                 725                 730                 735

 Leu Ser Pro Ala Ser Thr Glu Thr Asn Phe Ser Glu Leu Lys Thr
                 740                 745                 750

 Met Pro Asn Leu Gln Pro Ile Ser Ala Leu Pro Thr Lys Thr Gln
                 755                 760                 765

 Lys Gly Ile His Ser Gly Thr Trp Lys Leu Ser Pro Pro Arg Leu
                 770                 775                 780

 Met Ala Asn Ser Pro Ser His Leu Cys Glu Ile Gly Ser Leu Lys
                 785                 790                 795

 Glu Ile Thr Leu Ser Pro Val Ser Glu Ser His Ser Glu Glu Thr
                 800                 805                 810

 Ile Pro Ser Asp Ser Gly Ile Gly Thr Asp Asn Asn Ser Thr Ser
                 815                 820                 825

 Asp Gln Ala Glu Lys Ser Ser Glu Ser Arg Arg Arg Tyr Ser Phe
                 830                 835                 840

 Asp Phe Cys Ser Leu Asp Asn Pro Glu Ala Ile Pro Ser Asp Thr
                 845                 850                 855

 Ser Thr Lys Asn Arg His Gly His Arg Gln Lys His Leu Ile Val
                 860                 865                 870

 Asp Asn Phe Leu Ala His Glu Ser Leu Lys Lys Pro Lys His Lys
                 875                 880                 885

 Arg Lys Arg Lys Ser Leu Gln Asn Arg Asp Asp Leu Gln Phe Leu
                 890                 895                 900

 Ala Asp Leu Glu Glu Leu Ile Thr Lys Phe Gln Val Phe Arg Ile
                 905                 910                 915

 Ser His Arg Ser Tyr Thr Phe Tyr His Glu Asn Pro Tyr Pro Ser
                 920                 925                 930

 Ile Phe Arg Ile Asn Phe Asp His Tyr Tyr Pro Val Pro Tyr Ile
                 935                 940                 945

 Gln Tyr Asp Pro Leu Leu Tyr Leu Arg Arg Thr Ser Asp Leu Lys
                 950                 955                 960

 Ser Lys Lys Lys Arg Gly Arg Pro Ala Lys Thr Asn Asp Thr Met
                 965                 970                 975

 Thr Lys Val Pro Phe Leu Gln Gly Phe Ser Tyr Pro Ile Pro Ser
                 980                 985                 990

 Gly Ser Tyr Tyr Ala Pro Tyr Gly Met Pro Tyr Thr Ser Met Pro
                 995                1000                1005

 Met Met Asn Leu Gly Tyr Tyr Gly Gln Tyr Pro Ala Pro Leu Tyr
                1010                1015                1020

 Leu Ser His Thr Leu Gly Ala Ala Ser Pro Phe Met Arg Pro Thr
                1025                1030                1035

 Val Pro Pro Pro Gln Phe His Thr Asn Ser His Ile Lys Met Ser
                1040                1045                1050

 Gly Ala Ala Lys His Lys Ala Lys His Gly Val His Leu Gln Gly
                1055                1060                1065

 Pro Val Ser Met Gly Leu Gly Asp Met Gln Pro Ser Leu Asn Pro
                1070                1075                1080

 Pro Lys Val Gly Ser Ala Ser Leu Ser Ser Gly Arg Leu His Lys
                1085                1090                1095

 Arg Lys His Lys His Lys His Lys His Lys Glu Asp Arg Ile Leu
                1100                1105                1110

 Gly Thr His Asp Asn Leu Ser Gly Leu Phe Ala Gly Lys Ala Thr
                1115                1120                1125

 Gly Phe Ser Ser His Ile Leu Ser Glu Arg Leu Ser Ser Ala Asp
                1130                1135                1140

 Lys Glu Leu Pro Leu Val Ser Glu Lys Asn Lys His Lys Glu Lys
                1145                1150                1155

 Gln Lys His Gln His Ser Glu Ala Gly His Lys Ala Ser Lys Asn
                1160                1165                1170

 Asn Phe Glu Val Asp Thr Leu Ser Thr Leu Ser Leu Ser Asp Ala
                1175                1180                1185

 Gln His Trp Thr Gln Ala Lys Glu Lys Gly Asp Leu Ser Ser Glu
                1190                1195                1200

 Pro Val Asp Ser Cys Thr Lys Arg Tyr Ser Gly Ser Gly Gly Asp
                1205                1210                1215

 Gly Gly Ser Thr Arg Ser Glu Asn Leu Asp Val Phe Ser Glu Met
                1220                1225                1230

 Asn Pro Ser Asn Asp Lys Trp Asp Ser Asp Val Ser Gly Ser Lys
                1235                1240                1245

 Arg Arg Ser Tyr Glu Gly Phe Gly Thr Tyr Arg Glu Lys Asp Ile
                1250                1255                1260

 Gln Ala Phe Lys Met Asn Arg Lys Glu Arg Ser Ser Tyr Asp Ser
                1265                1270                1275

 Ser Met Ser Pro Gly Met Pro Ser Pro His Leu Lys Val Asp Gln
                1280                1285                1290

 Thr Ala Val His Ser Lys Asn Glu Gly Ser Val Pro Thr Met Met
                1295                1300                1305

 Thr Arg Lys Lys Pro Ala Ala Val Asp Ser Val Thr Ile Pro Pro
                1310                1315                1320

 Ala Pro Val Leu Ser Leu Leu Ala Ala Ser Ala Ala Thr Ser Asp
                1325                1330                1335

 Ala Val Gly Ser Ser Leu Lys Lys Arg Phe Lys Arg Arg Glu Ile
                1340                1345                1350

 Glu Ala Ile Gln Cys Glu Val Arg Lys Met Cys Asn Tyr Thr Lys
                1355                1360                1365

 Ile Leu Ser Thr Lys Lys Asn Leu Asp His Val Asn Lys Ile Leu
                1370                1375                1380

 Lys Ala Lys Arg Leu Gln Arg Gln Ser Lys Thr Gly Asn Asn Phe
                1385                1390                1395

 Val Lys Lys Arg Arg Gly Arg Pro Arg Lys Gln Pro Thr Gln Phe
                1400                1405                1410

 Asp Glu Asp Ser Arg Asp Gln Met Pro Val Leu Glu Lys Cys Ile
                1415                1420                1425

 Asp Leu Pro Ser Lys Arg Gly Gln Lys Pro Ser Leu Ser Pro Leu
                1430                1435                1440

 Val Leu Glu Pro Ala Ala Ser Gln Asp Thr Ile Met Ala Thr Ile
                1445                1450                1455

 Glu Ala Val Ile His Met Ala Arg Glu Ala Pro Pro Leu Pro Pro
                1460                1465                1470

 Pro Pro Pro Pro Pro Leu Pro Pro Pro Pro Pro Pro Pro Leu Pro
                1475                1480                1485

 Pro Pro Pro Pro Leu Pro Lys Thr Pro Arg Gly Gly Lys Arg Lys
                1490                1495                1500

 His Lys Pro Gln Ala Pro Ala Gln Pro Pro Gln Gln Ser Pro Pro
                1505                1510                1515

 Gln Gln Pro Leu Pro Gln Glu Glu Glu Val Lys Ala Lys Arg Gln
                1520                1525                1530

 Arg Lys Ser Arg Gly Ser Glu Ser Glu Val Leu Pro
                1535                1540

<210> 1457
<211> 4565
<212> DNA
<213> Homo sapien

<400> 1457
 gaattccggg cagcatcatc aaggcacata gattctctct ttgaacaatg 50

 cagctgctgc aggggatggg gaagggatgg cactggcaat tcaagactgc 100

 ctttcctact tcttcagtgc ctctttcacc aatatgaagt taaaaccagg 150

 atccttcaaa ccaaaaatgt ggtggaagaa agaaaaccgt gtctttcagc 200

 agcatgccat cggaaaagaa aattagcagt gcaaatgact gcatcagctt 250

 catgcaagct ggctgtgagt tgaagaaagt ccggccaaat tctcgcattt 300

 acaaccgttt tttcactctg gacacagacc ttcaagctct tcgctgggaa 350

 ccttcaaaga aagacctcga gaaagccaag cttgatattt ctgccataaa 400

 agagatcaga ctggggaaaa acacggaaac atttacaaac aatggccttg 450

 ctgaccagat ctgtgaggac tgtgcctttt ccatactcca cggggaaaac 500

 tatgagtctc tggacctagt tgccaattca gcagatgtgg caaacatctg 550

 ggtgtctggg ttacggtacc tggtttctcg aagtaagcag cctcttgatt 600

 ttatggaggg caaccagaac acaccacggt tcatgtggtt gaaaacagtg 650

 tttgaagcag cagatgttga tgggaatggg attatgttgg aagacacctc 700

 tgtagagtta ataaaacaac tcaaccctac tctgaaggaa gccaagatca 750

 ggttaaagtt taaagaaatc cagaagagca aggaaaaact aaccacccgc 800

 gtgaccgaag aggaattttg tgaagctttt tgtgaacttt gcaccaggcc 850

 agaagtgtat ttcttacttg tacagatatc taaaaacaaa gaatatttgg 900

 atgccaatga tctcatgctc tttttagaag ctgagcaagg agtcacccat 950

 atcaccgagg atatatgctt agacatcata aggagatacg aactttctga 1000

 agagggacgt caaaaagggt ttcttgcaat tgatggcttt acccagtatt 1050

 tattgtcatc agaatgtgac atttttgatc ctgagcaaaa gaaggttgcc 1100

 caagatatga cccagccatt atctcactac tatatcaatg cctctcataa 1150

 cacctatcta atagaagacc agttcagggg gccagctgac atcaatgggt 1200

 acattagagc tttgaaaatg ggctgtcgaa gcgttgaact cgatgtaagt 1250

 gatggttcag ataatgaacc aatcctttgt aatcgaaata acatgacaac 1300

 ccatgtttcc tttcgaagtg tcatagaggt aataaataaa tttgcctttg 1350

 ttgcttctga atacccactc attctttgct tgggaaatca ctgctccttg 1400

 ccgcagcaga aggtaatggc tcaacagatg aaaaaggtct ttggcaataa 1450

 actctatact gaagcacctt tgccctcaga atcctacctc ccatcaccag 1500

 aaaaattaaa aagaatgatc attgtgaaag gaaagaagtt gccttctgat 1550

 ccagatgtgt tagaaggaga agtaacagat gaagatgaag aagctcaaat 1600

 gtctcgaagg atgtcggtag attacaatgg tgagcagaag caaatccgac 1650

 tctgtaggga gctctctgat ttggtgtcta tttgtaaatc tgttcaatac 1700

 agggattttg aactatctat gaaaagccaa aactattggg aaatgtgttc 1750

 atttagtgaa acagaggcca gccgcattgc aaatgagtac ccagaggatt 1800

 ttgttaatta taataagaag ttcttatcaa gaatctatcc aagtgccatg 1850

 aggatcgatt ccagtaactt gaatccacag gacttttgga attgtggctg 1900

 tcagattgta gcaatgaatt ttcagactcc gggtccaatg atggaccttc 1950

 acacgggctg gtttcttcaa aacgggggat gtggttatgt tctaaggccg 2000

 tctataatgc gagatgaagt ttcttacttc agcgcaaata caaagggcat 2050

 tctacctggg gtgtctcctc tagctcttca tatcaagatc atcagtggtc 2100

 agaatttccc aaagcccaag ggagcttgtg ccaaagggga tgtcatagat 2150

 ccctatgttt gtatagagat acacggaatt ccagcggatt gttcggaaca 2200

 aagaactaaa actgtacagc aaaacagtga taatcctatt tttgatgaaa 2250

 cttttgagtt ccaagtaaac ctacctgagc tggccatgat ccgttttgtt 2300

 gttctggatg atgactacat tggggatgag tttatagggc aatatacgat 2350

 accatttgaa tgtttgcagc ctggatatcg gcatgttccc ctgcgttctt 2400

 ttgtgggtga catcatggag cacgtaaccc tttttgtcca catagcaata 2450

 actaatcgaa gtggaggagg aaaggcacag aagcgcagtc tttcagtgag 2500

 aatggggaag aaagttcggg aatataccat gctcaggaat atcggtctta 2550

 aaaccattga tgacatcttt aaaatagcgg ttcatccatt acgagaagcc 2600

 atagatatga gagaaaatat gcagaatgca atcgtgtcta ttaaggaact 2650

 atgtggactc cctccaattg ccagtctgaa gcagtgcctg ttaactctgt 2700

 catctcggct catcaccagt gacaatactc cttcagtctc acttgtgatg 2750

 aaagacagct ttccttacct ggagcctctg ggtgcaattc cagatgtgca 2800

 gaaaaagatg ctgactgctt atgatctgat gattcaagag agccggtttc 2850

 tcatagaaat ggcggacaca gtccaggaaa agattgtaca gtgtcagaaa 2900

 gcagggatgg agttccatga agaacttcat aatttggggg caaaagaagg 2950

 cttgaaggga agaaaactca acaaagcaac tgagagcttt gcttggaaca 3000

 ttacagtatt gaagggccaa ggagatctgt tgaagaatgc caagaatgaa 3050

 gctatagaaa acatgaagca gatccagctg gcatgcctgt cctgtggact 3100

 gagtaaagcc cccagcagca gtgctgaggc caagagcaag cgcagcctgg 3150

 aagccataga ggagaaggaa agtagtgagg agaatgggaa gctgtgactc 3200

 tgggcattat cgacacgttc acccatctta tcaaggactc tggtttctca 3250

 ttcttgtttt ctttctttaa atgttttata agttcacaaa atggtgccct 3300

 atatggggta ttggacatag atattttcac aatgtcagta tttcagtgta 3350

 gttaatttat ctaaattaaa gcctttagta tcagtgtttt aaattctgag 3400

 acatgtgtca acacccctgt gtggatgcct gtggaagagt gtgtgtgtgt 3450

 gtgtgtgtgt gtgtgtgtgt gtgtgtggca gagagagaga aagagagaga 3500

 gagaaattct gttaaaatct attctgtgtt gcattattca tttagtgagt 3550

 tattccttga tcattttggg acaattgttt taatctgaaa ttctaaagag 3600

 cacttactgt aacctgttgc tgtgtttaat ttgacttctc tgcctttgac 3650

 atttaattta gtgatcttag catagcttat tattgaagga agccaaattt 3700

 atcaaagcat acatgttttg gtagattaaa tatagattag aaaaattcct 3750

 aagaatcaga gtagaaataa aagtgaatga aagattaaac agatgatgag 3800

 aatttctaaa aagattagca aggtcatttc ttcagtcaga aaactttaaa 3850

 aaatatttat taaataaaat caatttttag gaagttttct gtagtcattt 3900

 actaaacata tgatttcact agaaaagctg atcataagtg aatttatacc 3950

 tacctgtgtg gctactctga aacacactga aagctctgtt gcaattagga 4000

 tttgatgtga cataatattg ttgtataatt tcgagatttg taggaaggtc 4050

 tcattcttcc aagctgagag tctagcactc attttctata acagatatgg 4100

 cagcttagag gtgttggctt tgtttggatg taattttagg ggtactaaaa 4150

 tttaaaattt aaagataatt gttcaacaat atcatatcat cacattgagc 4200

 tgatataaat tctgtgggtc cgataatatc tttgtgataa tttaagagct 4250

 aaccagttac cacacatcta tgatataacc ctaacacaca cagaaagcat 4300

 acatgcaaaa agaaatgact aattagggta catttataat tgcatctagg 4350

 taatttttac cctaatgtct tcataaagta cttgagtgta atgtttgtta 4400

 cctccaacag aactaaatgt tctatggtta tgaaagaata tatttattta 4450

 aagcattgct tttattttga aaagcttctt aattaatttg attaacaaat 4500

 atgctaattt ggggaaacct agagaagata attgttgaaa ttttgcaaat 4550

 ataaacatct cctat 4565

<210> 1458
<211> 997
<212> PRT
<213> Homo sapien

<400> 1458
 Met Pro Ser Glu Lys Lys Ile Ser Ser Ala Asn Asp Cys Ile Ser
   1               5                  10                  15

 Phe Met Gln Ala Gly Cys Glu Leu Lys Lys Val Arg Pro Asn Ser
                  20                  25                  30

 Arg Ile Tyr Asn Arg Phe Phe Thr Leu Asp Thr Asp Leu Gln Ala
                  35                  40                  45

 Leu Arg Trp Glu Pro Ser Lys Lys Asp Leu Glu Lys Ala Lys Leu
                  50                  55                  60

 Asp Ile Ser Ala Ile Lys Glu Ile Arg Leu Gly Lys Asn Thr Glu
                  65                  70                  75

 Thr Phe Thr Asn Asn Gly Leu Ala Asp Gln Ile Cys Glu Asp Cys
                  80                  85                  90

 Ala Phe Ser Ile Leu His Gly Glu Asn Tyr Glu Ser Leu Asp Leu
                  95                 100                 105

 Val Ala Asn Ser Ala Asp Val Ala Asn Ile Trp Val Ser Gly Leu
                 110                 115                 120

 Arg Tyr Leu Val Ser Arg Ser Lys Gln Pro Leu Asp Phe Met Glu
                 125                 130                 135

 Gly Asn Gln Asn Thr Pro Arg Phe Met Trp Leu Lys Thr Val Phe
                 140                 145                 150

 Glu Ala Ala Asp Val Asp Gly Asn Gly Ile Met Leu Glu Asp Thr
                 155                 160                 165

 Ser Val Glu Leu Ile Lys Gln Leu Asn Pro Thr Leu Lys Glu Ala
                 170                 175                 180

 Lys Ile Arg Leu Lys Phe Lys Glu Ile Gln Lys Ser Lys Glu Lys
                 185                 190                 195

 Leu Thr Thr Arg Val Thr Glu Glu Glu Phe Cys Glu Ala Phe Cys
                 200                 205                 210

 Glu Leu Cys Thr Arg Pro Glu Val Tyr Phe Leu Leu Val Gln Ile
                 215                 220                 225

 Ser Lys Asn Lys Glu Tyr Leu Asp Ala Asn Asp Leu Met Leu Phe
                 230                 235                 240

 Leu Glu Ala Glu Gln Gly Val Thr His Ile Thr Glu Asp Ile Cys
                 245                 250                 255

 Leu Asp Ile Ile Arg Arg Tyr Glu Leu Ser Glu Glu Gly Arg Gln
                 260                 265                 270

 Lys Gly Phe Leu Ala Ile Asp Gly Phe Thr Gln Tyr Leu Leu Ser
                 275                 280                 285

 Ser Glu Cys Asp Ile Phe Asp Pro Glu Gln Lys Lys Val Ala Gln
                 290                 295                 300

 Asp Met Thr Gln Pro Leu Ser His Tyr Tyr Ile Asn Ala Ser His
                 305                 310                 315

 Asn Thr Tyr Leu Ile Glu Asp Gln Phe Arg Gly Pro Ala Asp Ile
                 320                 325                 330

 Asn Gly Tyr Ile Arg Ala Leu Lys Met Gly Cys Arg Ser Val Glu
                 335                 340                 345

 Leu Asp Val Ser Asp Gly Ser Asp Asn Glu Pro Ile Leu Cys Asn
                 350                 355                 360

 Arg Asn Asn Met Thr Thr His Val Ser Phe Arg Ser Val Ile Glu
                 365                 370                 375

 Val Ile Asn Lys Phe Ala Phe Val Ala Ser Glu Tyr Pro Leu Ile
                 380                 385                 390

 Leu Cys Leu Gly Asn His Cys Ser Leu Pro Gln Gln Lys Val Met
                 395                 400                 405

 Ala Gln Gln Met Lys Lys Val Phe Gly Asn Lys Leu Tyr Thr Glu
                 410                 415                 420

 Ala Pro Leu Pro Ser Glu Ser Tyr Leu Pro Ser Pro Glu Lys Leu
                 425                 430                 435

 Lys Arg Met Ile Ile Val Lys Gly Lys Lys Leu Pro Ser Asp Pro
                 440                 445                 450

 Asp Val Leu Glu Gly Glu Val Thr Asp Glu Asp Glu Glu Ala Gln
                 455                 460                 465

 Met Ser Arg Arg Met Ser Val Asp Tyr Asn Gly Glu Gln Lys Gln
                 470                 475                 480

 Ile Arg Leu Cys Arg Glu Leu Ser Asp Leu Val Ser Ile Cys Lys
                 485                 490                 495

 Ser Val Gln Tyr Arg Asp Phe Glu Leu Ser Met Lys Ser Gln Asn
                 500                 505                 510

 Tyr Trp Glu Met Cys Ser Phe Ser Glu Thr Glu Ala Ser Arg Ile
                 515                 520                 525

 Ala Asn Glu Tyr Pro Glu Asp Phe Val Asn Tyr Asn Lys Lys Phe
                 530                 535                 540

 Leu Ser Arg Ile Tyr Pro Ser Ala Met Arg Ile Asp Ser Ser Asn
                 545                 550                 555

 Leu Asn Pro Gln Asp Phe Trp Asn Cys Gly Cys Gln Ile Val Ala
                 560                 565                 570

 Met Asn Phe Gln Thr Pro Gly Pro Met Met Asp Leu His Thr Gly
                 575                 580                 585

 Trp Phe Leu Gln Asn Gly Gly Cys Gly Tyr Val Leu Arg Pro Ser
                 590                 595                 600

 Ile Met Arg Asp Glu Val Ser Tyr Phe Ser Ala Asn Thr Lys Gly
                 605                 610                 615

 Ile Leu Pro Gly Val Ser Pro Leu Ala Leu His Ile Lys Ile Ile
                 620                 625                 630

 Ser Gly Gln Asn Phe Pro Lys Pro Lys Gly Ala Cys Ala Lys Gly
                 635                 640                 645

 Asp Val Ile Asp Pro Tyr Val Cys Ile Glu Ile His Gly Ile Pro
                 650                 655                 660

 Ala Asp Cys Ser Glu Gln Arg Thr Lys Thr Val Gln Gln Asn Ser
                 665                 670                 675

 Asp Asn Pro Ile Phe Asp Glu Thr Phe Glu Phe Gln Val Asn Leu
                 680                 685                 690

 Pro Glu Leu Ala Met Ile Arg Phe Val Val Leu Asp Asp Asp Tyr
                 695                 700                 705

 Ile Gly Asp Glu Phe Ile Gly Gln Tyr Thr Ile Pro Phe Glu Cys
                 710                 715                 720

 Leu Gln Pro Gly Tyr Arg His Val Pro Leu Arg Ser Phe Val Gly
                 725                 730                 735

 Asp Ile Met Glu His Val Thr Leu Phe Val His Ile Ala Ile Thr
                 740                 745                 750

 Asn Arg Ser Gly Gly Gly Lys Ala Gln Lys Arg Ser Leu Ser Val
                 755                 760                 765

 Arg Met Gly Lys Lys Val Arg Glu Tyr Thr Met Leu Arg Asn Ile
                 770                 775                 780

 Gly Leu Lys Thr Ile Asp Asp Ile Phe Lys Ile Ala Val His Pro
                 785                 790                 795

 Leu Arg Glu Ala Ile Asp Met Arg Glu Asn Met Gln Asn Ala Ile
                 800                 805                 810

 Val Ser Ile Lys Glu Leu Cys Gly Leu Pro Pro Ile Ala Ser Leu
                 815                 820                 825

 Lys Gln Cys Leu Leu Thr Leu Ser Ser Arg Leu Ile Thr Ser Asp
                 830                 835                 840

 Asn Thr Pro Ser Val Ser Leu Val Met Lys Asp Ser Phe Pro Tyr
                 845                 850                 855

 Leu Glu Pro Leu Gly Ala Ile Pro Asp Val Gln Lys Lys Met Leu
                 860                 865                 870

 Thr Ala Tyr Asp Leu Met Ile Gln Glu Ser Arg Phe Leu Ile Glu
                 875                 880                 885

 Met Ala Asp Thr Val Gln Glu Lys Ile Val Gln Cys Gln Lys Ala
                 890                 895                 900

 Gly Met Glu Phe His Glu Glu Leu His Asn Leu Gly Ala Lys Glu
                 905                 910                 915

 Gly Leu Lys Gly Arg Lys Leu Asn Lys Ala Thr Glu Ser Phe Ala
                 920                 925                 930

 Trp Asn Ile Thr Val Leu Lys Gly Gln Gly Asp Leu Leu Lys Asn
                 935                 940                 945

 Ala Lys Asn Glu Ala Ile Glu Asn Met Lys Gln Ile Gln Leu Ala
                 950                 955                 960

 Cys Leu Ser Cys Gly Leu Ser Lys Ala Pro Ser Ser Ser Ala Glu
                 965                 970                 975

 Ala Lys Ser Lys Arg Ser Leu Glu Ala Ile Glu Glu Lys Glu Ser
                 980                 985                 990

 Ser Glu Glu Asn Gly Lys Leu
                 995

<210> 1459
<211> 938
<212> DNA
<213> Homo sapien

<400> 1459
 caagagagag agagaggtgc aagccccaaa gcgagcgaca tgtccctttg 50

 gggagcagtc cctctgcacc ccagagtgag gaggacgcag gggtcagagg 100

 tggctacagg gcaggcagag gaggcacctg tagggggtgg tgggctggtg 150

 gcccaggaga agtcaggaag ggagcccagc tggtgacaag agagcccaga 200

 ggtgcctggg gctgagtgtg agagcccgga agatttcagc catgcctcac 250

 agctccgaca gcagtgactc cagcttcagc cgctctcctc cccctggcaa 300

 acaggactca tctgatgatg tgagaagagt tcagaggagg gagaaaaatc 350

 gtattgccgc ccagaagagc cgacagaggc agacacagaa ggccgacacc 400

 ctgcacctgg agagcgaaga cctggagaaa cagaacgcgg ctctacgcaa 450

 ggagatcaag cagctcacag aggaactgaa gtacttcacg tcggtgctga 500

 acagccacga gcccctgtgc tcggtgctgg ccgccagcac gccctcgccc 550

 cccgaggtgg tgtacagcgc ccacgcattc caccaacctc atgtcagctc 600

 cccgcgcttc cagccctgag cttccgatgc ggggagagca gagcctcggg 650

 aggggcacac agactgtggc agagctgcgc ccatcccgca gaggcccctg 700

 tccacctgga gacccggaga cagaggcctg gacaaggagt gaacacggga 750

 actgtcacga ctggaagggc gtgaggcctc ccagcagtgc cgcagcgttt 800

 cgaggggcgt gtgctggacc ccaccactgt gggttgcagg cccaatgcag 850

 aagagtatta agaaagatgc tcaagtccca tggcacagag caaggcgggc 900

 agggaacggt tatttttcta aataaatgct ttaaaaga 938

<210> 1460
<211> 125
<212> PRT
<213> Homo sapien

<400> 1460
 Met Pro His Ser Ser Asp Ser Ser Asp Ser Ser Phe Ser Arg Ser
   1               5                  10                  15

 Pro Pro Pro Gly Lys Gln Asp Ser Ser Asp Asp Val Arg Arg Val
                  20                  25                  30

 Gln Arg Arg Glu Lys Asn Arg Ile Ala Ala Gln Lys Ser Arg Gln
                  35                  40                  45

 Arg Gln Thr Gln Lys Ala Asp Thr Leu His Leu Glu Ser Glu Asp
                  50                  55                  60

 Leu Glu Lys Gln Asn Ala Ala Leu Arg Lys Glu Ile Lys Gln Leu
                  65                  70                  75

 Thr Glu Glu Leu Lys Tyr Phe Thr Ser Val Leu Asn Ser His Glu
                  80                  85                  90

 Pro Leu Cys Ser Val Leu Ala Ala Ser Thr Pro Ser Pro Pro Glu
                  95                 100                 105

 Val Val Tyr Ser Ala His Ala Phe His Gln Pro His Val Ser Ser
                 110                 115                 120

 Pro Arg Phe Gln Pro
                 125

<210> 1461
<211> 3299
<212> DNA
<213> Homo sapien

<400> 1461
 ccacgcgtcc gtgcttttcc acagaaggtt agaccctgaa agagatggct 50

 cagcaccacc tatggatctt gctcctttgc ctgcaaacct ggccggaagc 100

 agctggaaaa gactcagaaa tcttcacagt gaatgggatt ctgggagagt 150

 cagtcacttt ccctgtaaat atccaagaac cacggcaagt taaaatcatt 200

 gcttggactt ctaaaacatc tgttgcttat gtaacaccag gagactcaga 250

 aacagcaccc gtagttactg tgacccacag aaattattat gaacggatac 300

 atgccttagg tccgaactac aatctggtca ttagcgatct gaggatggaa 350

 gacgcaggag actacaaagc agacataaat acacaggctg atccctacac 400

 caccaccaag cgctacaacc tgcaaatcta tcgtcggctt gggaaaccaa 450

 aaattacaca gagtttaatg gcatctgtga acagcacctg taatgtcaca 500

 ctgacatgct ctgtagagaa agaagaaaag aatgtgacat acaattggag 550

 tcccctggga gaagagggta atgtccttca aatcttccag actcctgagg 600

 accaagagct gacttacacg tgtacagccc agaaccctgt cagcaacaat 650

 tctgactcca tctctgcccg gcagctctgt gcagacatcg caatgggctt 700

 ccgtactcac cacaccgggt tgctgagcgt gctggctatg ttctttctgc 750

 ttgttctcat tctgtcttca gtgtttttgt tccgtttgtt caagagaaga 800

 caagatgctg cctcaaagaa aaccatatac acatatatca tggcttcaag 850

 gaacacccag ccagcagagt ccagaatcta tgatgaaatc ctgcagtcca 900

 aggtgcttcc ctccaaggaa gagccagtga acacagttta ttccgaagtg 950

 cagtttgctg ataagatggg gaaagccagc acacaggaca gtaaacctcc 1000

 tgggacttca agctatgaaa ttgtgatcta ggctgctggg ctgaattctc 1050

 cctctggaaa ctgagttaca accaccaata ctggcaggtt ccctggatcc 1100

 agatcttctc tgcccaactc ttactgggag attgcaaact gccacatctc 1150

 agcctgtaag caaagcagga aaccttctgc tgggcatagc ttgtgcctaa 1200

 atggacaaat ggatgcatac ccttcctgaa atgactccct tctgaatgaa 1250

 tgacaaagca ggttacctag tatagttttc ccaaacttct tcccatcata 1300

 gcacatgtag aaaataatat ttttatggca cactgggata aacaagcaag 1350

 attgctcact tctggaagct gcatatgact agaggcctct tgtgactgga 1400

 ggtaacaacc ctgcccagta actgtgggag aaggggatca atattttgca 1450

 cacctgtaat aggccatggc acaccagcca agatgctctg ctcacagtca 1500

 gtatgtgtga agatccctgg tgcgtggcct tcaccacgca tcttgagcaa 1550

 attaggaaaa tgtacccttc gcttgaggca gatgcagccc ttcccccgag 1600

 tgcatggctt ggagagcaga atgtgggctg catataagca cactcatccc 1650

 tttgtctggg aatctttgtg cagggcataa caggcttagt aagtccaaac 1700

 acagatgaca gtgctgtgtg ggtctctgtc agagttgtgg ctctcagcca 1750

 tgtagacaca ctctccaaat ggagtgttgg aaaatgttct ttctgcaggg 1800

 tctagagact gctgggacac ttttcttgga gtgctacttc agaagcctta 1850

 taggattttc tttctggcca agatttcctt ctgtatcact ccaagcagcc 1900

 tcagcagaag aagcagccat gcccagtatt cccactctcc aaaaggaact 1950

 gaccagctta tatttctcac acttctgggg aactgggtat aatccaacca 2000

 tcaaaataga agaccttgca agaagcagag tcattctcca gaaggaactt 2050

 gggagatgat ggtgcagatg atgaaactgg gttcatccca gttccaaaga 2100

 ctcagagaac tagagtttaa gctgaggcag agtgccgcca ccctggcatg 2150

 ccccacaaac agatcaccag ccagcttaca caggcattaa ctctcctcaa 2200

 tgaggaagaa tcattcacaa ctgagcaaga cattcatatg atcatttaag 2250

 gaagtgtttc ccttatgtgt tagcaagtat aatcggctaa ctcctaaatc 2300

 ccaatgaata gtcctaggct ggacagcaat gggctgcaat taggcagata 2350

 aagacatcag tcccagtaaa tgaatccata gactcatcta gcaccaacta 2400

 ccattagcac tatgttagga gctgcaaggc cccaaagtag aagatgtgca 2450

 taatgtctgc tcttgtgtag ctcaggagac aattccagca cagacactac 2500

 agttaacgct gaactgcagc tgcaagtaat agcatgaaca gtcagaaaaa 2550

 taccttatga gggggcaggg ctgaagctgg gccttgaagg atggatgaaa 2600

 tttggataga gaatgaggaa gacagagggc ctccaagtga gagaagcatg 2650

 aaaaatgagc aggggcctgg atcagtgggg tgtattcaga gcacctctcc 2700

 agatgcacca tgcatgctca cagtcccttg cctatgtgtg gcagagtgtc 2750

 ccagccagat gtgtgccccc accccatgtc catttacatg tccttcaatg 2800

 cccacctcaa aaggtacctc ttctgtaaag ctttccctgg tatcaggaat 2850

 caaaattaat cagggatctt ttcacactgc tgttttttcc tctttggtcc 2900

 ttctatcact aaaactcatc tcattcagcc ttacagcata actaattatt 2950

 tgttttcctc actacattgt acatgtggga attacagata aacggaagcc 3000

 ggctggggtg gtggctcacg cctgtaaccc caacactttg ggaggccaag 3050

 gcaggcggat cacctgaggt caggagttcg agattagtct ggccaacatg 3100

 gtgaaacccc atctctacta aaaatacgaa attagccagg tgtggtggca 3150

 cacatctgta gtcccagcta ctctggaggc tgagacagga gaatcgcttg 3200

 aacccaggaa gtggaggttg cagtgagctg agatcacacc actgcactcc 3250

 agcctgggag agagagagtg agtctccatc tcaaaaaaaa aaaaaaaaa 3299

<210> 1462
<211> 328
<212> PRT
<213> Homo sapien

<400> 1462
 Met Ala Gln His His Leu Trp Ile Leu Leu Leu Cys Leu Gln Thr
   1               5                  10                  15

 Trp Pro Glu Ala Ala Gly Lys Asp Ser Glu Ile Phe Thr Val Asn
                  20                  25                  30

 Gly Ile Leu Gly Glu Ser Val Thr Phe Pro Val Asn Ile Gln Glu
                  35                  40                  45

 Pro Arg Gln Val Lys Ile Ile Ala Trp Thr Ser Lys Thr Ser Val
                  50                  55                  60

 Ala Tyr Val Thr Pro Gly Asp Ser Glu Thr Ala Pro Val Val Thr
                  65                  70                  75

 Val Thr His Arg Asn Tyr Tyr Glu Arg Ile His Ala Leu Gly Pro
                  80                  85                  90

 Asn Tyr Asn Leu Val Ile Ser Asp Leu Arg Met Glu Asp Ala Gly
                  95                 100                 105

 Asp Tyr Lys Ala Asp Ile Asn Thr Gln Ala Asp Pro Tyr Thr Thr
                 110                 115                 120

 Thr Lys Arg Tyr Asn Leu Gln Ile Tyr Arg Arg Leu Gly Lys Pro
                 125                 130                 135

 Lys Ile Thr Gln Ser Leu Met Ala Ser Val Asn Ser Thr Cys Asn
                 140                 145                 150

 Val Thr Leu Thr Cys Ser Val Glu Lys Glu Glu Lys Asn Val Thr
                 155                 160                 165

 Tyr Asn Trp Ser Pro Leu Gly Glu Glu Gly Asn Val Leu Gln Ile
                 170                 175                 180

 Phe Gln Thr Pro Glu Asp Gln Glu Leu Thr Tyr Thr Cys Thr Ala
                 185                 190                 195

 Gln Asn Pro Val Ser Asn Asn Ser Asp Ser Ile Ser Ala Arg Gln
                 200                 205                 210

 Leu Cys Ala Asp Ile Ala Met Gly Phe Arg Thr His His Thr Gly
                 215                 220                 225

 Leu Leu Ser Val Leu Ala Met Phe Phe Leu Leu Val Leu Ile Leu
                 230                 235                 240

 Ser Ser Val Phe Leu Phe Arg Leu Phe Lys Arg Arg Gln Asp Ala
                 245                 250                 255

 Ala Ser Lys Lys Thr Ile Tyr Thr Tyr Ile Met Ala Ser Arg Asn
                 260                 265                 270

 Thr Gln Pro Ala Glu Ser Arg Ile Tyr Asp Glu Ile Leu Gln Ser
                 275                 280                 285

 Lys Val Leu Pro Ser Lys Glu Glu Pro Val Asn Thr Val Tyr Ser
                 290                 295                 300

 Glu Val Gln Phe Ala Asp Lys Met Gly Lys Ala Ser Thr Gln Asp
                 305                 310                 315

 Ser Lys Pro Pro Gly Thr Ser Ser Tyr Glu Ile Val Ile
                 320                 325

<210> 1463
<211> 5041
<212> DNA
<213> Homo sapien

<400> 1463
 gcggccgcga ctattcggta cctgaaaaca acgatggcat ggaaaacact 50

 tcccatttac ctgttgttgc tgctgtctgt tttcgtgatt cagcaagttt 100

 catctcaaga tttatcaagc tgtgcaggga gatgtgggga agggtattct 150

 agagatgcca cctgcaactg tgattataac tgtcaacact acatggagtg 200

 ctgccctgat ttcaagagag tctgcactgc ggagctttcc tgtaaaggcc 250

 gctgctttga gtccttcgag agagggaggg agtgtgactg cgacgcccaa 300

 tgtaagaagt atgacaagtg ctgtcccgat tatgagagtt tctgtgcaga 350

 agtgcataat cccacatcac caccatcttc aaagaaagca cctccacctt 400

 caggagcatc tcaaaccatc aaatcaacaa ccaaacgttc acccaaacca 450

 ccaaacaaga agaagactaa gaaagttata gaatcagagg aaataacaga 500

 agaacattct gtttctgaaa atcaagagtc ctcctcctcc tcctcctctt 550

 cctcttcttc ttcaacaatt tggaaaatca agtcttccaa aaattcagct 600

 gctaatagag aattacagaa gaaactcaaa gtaaaagata acaagaagaa 650

 cagaactaaa aagaaaccta cccccaaacc accagttgta gatgaagctg 700

 gaagtggatt ggacaatggt gacttcaagg tcacaactcc tgacacgtct 750

 accacccaac acaataaagt cagcacatct cccaagatca caacagcaaa 800

 accaataaat cccagaccca gtcttccacc taattctgat acatctaaag 850

 agacgtcttt gacagtgaat aaagagacaa cagttgaaac taaagaaact 900

 actacaacaa ataaacagac ttcaactgat ggaaaagaga agactacttc 950

 cgctaaagag acacaaagta tagagaaaac atctgctaaa gatttagcac 1000

 ccacatctaa agtgctggct aaacctacac ccaaagctga aactacaacc 1050

 aaaggccctg ctctcaccac tcccaaggag cccacgccca ccactcccaa 1100

 ggagcctgca tctaccacac ccaaagagcc cacacctacc accatcaagt 1150

 ctgcacccac cacccccaag gagcctgcac ccaccaccac caagtctgca 1200

 cccaccactc ccaaggagcc tgcacccacc accaccaagg agcctgcacc 1250

 caccactccc aaggagcctg cacccaccac caccaaggag cctgcaccca 1300

 ccaccaccaa gtctgcaccc accactccca aggagcctgc acccaccacc 1350

 cccaagaagc ctgccccaac tacccccaag gagcctgcac ccaccactcc 1400

 caaggagcct acacccacca ctcccaagga gcctgcaccc accaccaagg 1450

 agcctgcacc caccactccc aaagagcctg cacccactgc ccccaagaag 1500

 cctgccccaa ctacccccaa ggagcctgca cccaccactc ccaaggagcc 1550

 tgcacccacc accaccaagg agccttcacc caccactccc aaggagcctg 1600

 cacccaccac caccaagtct gcacccacca ctaccaagga gcctgcaccc 1650

 accactacca agtctgcacc caccactccc aaggagcctt cacccaccac 1700

 caccaaggag cctgcaccca ccactcccaa ggagcctgca cccaccaccc 1750

 ccaagaagcc tgccccaact acccccaagg agcctgcacc caccactccc 1800

 aaggaacctg cacccaccac caccaagaag cctgcaccca ccgctcccaa 1850

 agagcctgcc ccaactaccc ccaaggagac tgcacccacc acccccaaga 1900

 agctcacgcc caccaccccc gagaagctcg cacccaccac ccctgagaag 1950

 cccgcaccca ccacccctga ggagctcgca cccaccaccc ctgaggagcc 2000

 cacacccacc acccctgagg agcctgctcc caccactccc aaggcagcgg 2050

 ctcccaacac ccctaaggag cctgctccaa ctacccctaa ggagcctgct 2100

 ccaactaccc ctaaggagcc tgctccaact acccctaagg agactgctcc 2150

 aactacccct aaagggactg ctccaactac cctcaaggaa cctgcaccca 2200

 ctactcccaa gaagcctgcc cccaaggagc ttgcacccac caccaccaag 2250

 gagcccacat ccaccacctc tgacaagccc gctccaacta cccctaaggg 2300

 gactgctcca actaccccta aggagcctgc tccaactacc cctaaggagc 2350

 ctgctccaac tacccctaag gggactgctc caactaccct caaggaacct 2400

 gcacccacta ctcccaagaa gcctgccccc aaggagcttg cacccaccac 2450

 caccaagggg cccacatcca ccacctctga caagcctgct ccaactacac 2500

 ctaaggagac tgctccaact acccccaagg agcctgcacc cactaccccc 2550

 aagaagcctg ctccaactac tcctgagaca cctcctccaa ccacttcaga 2600

 ggtctctact ccaactacca ccaaggagcc taccactatc cacaaaagcc 2650

 ctgatgaatc aactcctgag ctttctgcag aacccacacc aaaagctctt 2700

 gaaaacagtc ccaaggaacc tggtgtacct acaactaaga ctcctgcagc 2750

 gactaaacct gaaatgacta caacagctaa agacaagaca acagaaagag 2800

 acttacgtac tacacctgaa actacaactg ctgcacctaa gatgacaaaa 2850

 gagacagcaa ctacaacaga aaaaactacc gaatccaaaa taacagctac 2900

 aaccacacaa gtaacatcta ccacaactca agataccaca ccattcaaaa 2950

 ttactactct taaaacaact actcttgcac ccaaagtaac tacaacaaaa 3000

 aagacaatta ctaccactga gattatgaac aaacctgaag aaacagctaa 3050

 accaaaagac agagctacta attctaaagc gacaactcct aaacctcaaa 3100

 agccaaccaa agcacccaaa aaacccactt ctaccaaaaa gccaaaaaca 3150

 atgcctagag tgagaaaacc aaagacgaca ccaactcccc gcaagatgac 3200

 atcaacaatg ccagaattga accctacctc aagaatagca gaagccatgc 3250

 tccaaaccac caccagacct aaccaaactc caaactccaa actagttgaa 3300

 gtaaatccaa agagtgaaga tgcaggtggt gctgaaggag aaacacctca 3350

 tatgcttctc aggccccatg tgttcatgcc tgaagttact cccgacatgg 3400

 attacttacc gagagtaccc aatcaaggca ttatcatcaa tcccatgctt 3450

 tccgatgaga ccaatatatg caatggtaag ccagtagatg gactgactac 3500

 tttgcgcaat gggacattag ttgcattccg aggtcattat ttctggatgc 3550

 taagtccatt cagtccacca tctccagctc gcagaattac tgaagtttgg 3600

 ggtattcctt cccccattga tactgttttt actaggtgca actgtgaagg 3650

 aaaaactttc ttctttaagg attctcagta ctggcgtttt accaatgata 3700

 taaaagatgc agggtacccc aaaccaattt tcaaaggatt tggaggacta 3750

 actggacaaa tagtggcagc gctttcaaca gctaaatata agaactggcc 3800

 tgaatctgtg tattttttca agagaggtgg cagcattcag cagtatattt 3850

 ataaacagga acctgtacag aagtgccctg gaagaaggcc tgctctaaat 3900

 tatccagtgt atggagaaat gacacaggtt aggagacgtc gctttgaacg 3950

 tgctatagga ccttctcaaa cacacaccat cagaattcaa tattcacctg 4000

 ccagactggc ttatcaagac aaaggtgtcc ttcataatga agttaaagtg 4050

 agtatactgt ggagaggact tccaaatgtg gttacctcag ctatatcact 4100

 gcccaacatc agaaaacctg acggctatga ttactatgcc ttttctaaag 4150

 atcaatacta taacattgat gtgcctagta gaacagcaag agcaattact 4200

 actcgttctg ggcagacctt atccaaagtc tggtacaact gtccttagac 4250

 tgatgagcaa aggaggagtc aactaatgaa gaaatgaata ataaattttg 4300

 acactgaaaa acattttatt aataaagaat attgacatga gtataccagt 4350

 ttatatataa aaatgttttt aaacttgaca atcattacac taaaacagat 4400

 ttgataatct tattcacagt tgttattgtt tacagaccat ttaattaata 4450

 tttcctctgt ttattcctcc tctccctccc attgcatggc tcacacctgt 4500

 aaaagaaaaa agaatcaaat tgaatatatc ttttaagaat tcaaaactag 4550

 tgtattcact taccctagtt cattataaaa aatatctagg cattgtggat 4600

 ataaaactgt tgggtattct acaacttcaa tggaaattat tacaagcaga 4650

 ttaatccctc tttttgtgac acaagtacaa tctaaaagtt atattggaaa 4700

 acatggaaat attaaaattt tacactttta ctagctaaaa cataatcaca 4750

 aagctttatc gtgttgtata aaaaaattaa caatataatg gcaataggta 4800

 gagatacaac aaatgaatat aacactataa cacttcatat tttccaaatc 4850

 ttaatttgga tttaaggaag aaatcaataa atataaaata taagcacata 4900

 tttattatat atctaaggta tacaaatctg tctacatgaa gtttacagat 4950

 tggtaaatat cacctgctca acatgtaatt atttaataaa actttggaac 5000

 attaaaaaaa taaattggag gcttaaaaaa aaaaaaaaaa a 5041

<210> 1464
<211> 1404
<212> PRT
<213> Homo sapien

<400> 1464
 Met Ala Trp Lys Thr Leu Pro Ile Tyr Leu Leu Leu Leu Leu Ser
   1               5                  10                  15

 Val Phe Val Ile Gln Gln Val Ser Ser Gln Asp Leu Ser Ser Cys
                  20                  25                  30

 Ala Gly Arg Cys Gly Glu Gly Tyr Ser Arg Asp Ala Thr Cys Asn
                  35                  40                  45

 Cys Asp Tyr Asn Cys Gln His Tyr Met Glu Cys Cys Pro Asp Phe
                  50                  55                  60

 Lys Arg Val Cys Thr Ala Glu Leu Ser Cys Lys Gly Arg Cys Phe
                  65                  70                  75

 Glu Ser Phe Glu Arg Gly Arg Glu Cys Asp Cys Asp Ala Gln Cys
                  80                  85                  90

 Lys Lys Tyr Asp Lys Cys Cys Pro Asp Tyr Glu Ser Phe Cys Ala
                  95                 100                 105

 Glu Val His Asn Pro Thr Ser Pro Pro Ser Ser Lys Lys Ala Pro
                 110                 115                 120

 Pro Pro Ser Gly Ala Ser Gln Thr Ile Lys Ser Thr Thr Lys Arg
                 125                 130                 135

 Ser Pro Lys Pro Pro Asn Lys Lys Lys Thr Lys Lys Val Ile Glu
                 140                 145                 150

 Ser Glu Glu Ile Thr Glu Glu His Ser Val Ser Glu Asn Gln Glu
                 155                 160                 165

 Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Thr Ile Trp
                 170                 175                 180

 Lys Ile Lys Ser Ser Lys Asn Ser Ala Ala Asn Arg Glu Leu Gln
                 185                 190                 195

 Lys Lys Leu Lys Val Lys Asp Asn Lys Lys Asn Arg Thr Lys Lys
                 200                 205                 210

 Lys Pro Thr Pro Lys Pro Pro Val Val Asp Glu Ala Gly Ser Gly
                 215                 220                 225

 Leu Asp Asn Gly Asp Phe Lys Val Thr Thr Pro Asp Thr Ser Thr
                 230                 235                 240

 Thr Gln His Asn Lys Val Ser Thr Ser Pro Lys Ile Thr Thr Ala
                 245                 250                 255

 Lys Pro Ile Asn Pro Arg Pro Ser Leu Pro Pro Asn Ser Asp Thr
                 260                 265                 270

 Ser Lys Glu Thr Ser Leu Thr Val Asn Lys Glu Thr Thr Val Glu
                 275                 280                 285

 Thr Lys Glu Thr Thr Thr Thr Asn Lys Gln Thr Ser Thr Asp Gly
                 290                 295                 300

 Lys Glu Lys Thr Thr Ser Ala Lys Glu Thr Gln Ser Ile Glu Lys
                 305                 310                 315

 Thr Ser Ala Lys Asp Leu Ala Pro Thr Ser Lys Val Leu Ala Lys
                 320                 325                 330

 Pro Thr Pro Lys Ala Glu Thr Thr Thr Lys Gly Pro Ala Leu Thr
                 335                 340                 345

 Thr Pro Lys Glu Pro Thr Pro Thr Thr Pro Lys Glu Pro Ala Ser
                 350                 355                 360

 Thr Thr Pro Lys Glu Pro Thr Pro Thr Thr Ile Lys Ser Ala Pro
                 365                 370                 375

 Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Thr Lys Ser Ala Pro
                 380                 385                 390

 Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Thr Lys Glu Pro Ala
                 395                 400                 405

 Pro Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Thr Lys Glu Pro
                 410                 415                 420

 Ala Pro Thr Thr Thr Lys Ser Ala Pro Thr Thr Pro Lys Glu Pro
                 425                 430                 435

 Ala Pro Thr Thr Pro Lys Lys Pro Ala Pro Thr Thr Pro Lys Glu
                 440                 445                 450

 Pro Ala Pro Thr Thr Pro Lys Glu Pro Thr Pro Thr Thr Pro Lys
                 455                 460                 465

 Glu Pro Ala Pro Thr Thr Lys Glu Pro Ala Pro Thr Thr Pro Lys
                 470                 475                 480

 Glu Pro Ala Pro Thr Ala Pro Lys Lys Pro Ala Pro Thr Thr Pro
                 485                 490                 495

 Lys Glu Pro Ala Pro Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr
                 500                 505                 510

 Thr Lys Glu Pro Ser Pro Thr Thr Pro Lys Glu Pro Ala Pro Thr
                 515                 520                 525

 Thr Thr Lys Ser Ala Pro Thr Thr Thr Lys Glu Pro Ala Pro Thr
                 530                 535                 540

 Thr Thr Lys Ser Ala Pro Thr Thr Pro Lys Glu Pro Ser Pro Thr
                 545                 550                 555

 Thr Thr Lys Glu Pro Ala Pro Thr Thr Pro Lys Glu Pro Ala Pro
                 560                 565                 570

 Thr Thr Pro Lys Lys Pro Ala Pro Thr Thr Pro Lys Glu Pro Ala
                 575                 580                 585

 Pro Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Thr Lys Lys Pro
                 590                 595                 600

 Ala Pro Thr Ala Pro Lys Glu Pro Ala Pro Thr Thr Pro Lys Glu
                 605                 610                 615

 Thr Ala Pro Thr Thr Pro Lys Lys Leu Thr Pro Thr Thr Pro Glu
                 620                 625                 630

 Lys Leu Ala Pro Thr Thr Pro Glu Lys Pro Ala Pro Thr Thr Pro
                 635                 640                 645

 Glu Glu Leu Ala Pro Thr Thr Pro Glu Glu Pro Thr Pro Thr Thr
                 650                 655                 660

 Pro Glu Glu Pro Ala Pro Thr Thr Pro Lys Ala Ala Ala Pro Asn
                 665                 670                 675

 Thr Pro Lys Glu Pro Ala Pro Thr Thr Pro Lys Glu Pro Ala Pro
                 680                 685                 690

 Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Pro Lys Glu Thr Ala
                 695                 700                 705

 Pro Thr Thr Pro Lys Gly Thr Ala Pro Thr Thr Leu Lys Glu Pro
                 710                 715                 720

 Ala Pro Thr Thr Pro Lys Lys Pro Ala Pro Lys Glu Leu Ala Pro
                 725                 730                 735

 Thr Thr Thr Lys Glu Pro Thr Ser Thr Thr Ser Asp Lys Pro Ala
                 740                 745                 750

 Pro Thr Thr Pro Lys Gly Thr Ala Pro Thr Thr Pro Lys Glu Pro
                 755                 760                 765

 Ala Pro Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Pro Lys Gly
                 770                 775                 780

 Thr Ala Pro Thr Thr Leu Lys Glu Pro Ala Pro Thr Thr Pro Lys
                 785                 790                 795

 Lys Pro Ala Pro Lys Glu Leu Ala Pro Thr Thr Thr Lys Gly Pro
                 800                 805                 810

 Thr Ser Thr Thr Ser Asp Lys Pro Ala Pro Thr Thr Pro Lys Glu
                 815                 820                 825

 Thr Ala Pro Thr Thr Pro Lys Glu Pro Ala Pro Thr Thr Pro Lys
                 830                 835                 840

 Lys Pro Ala Pro Thr Thr Pro Glu Thr Pro Pro Pro Thr Thr Ser
                 845                 850                 855

 Glu Val Ser Thr Pro Thr Thr Thr Lys Glu Pro Thr Thr Ile His
                 860                 865                 870

 Lys Ser Pro Asp Glu Ser Thr Pro Glu Leu Ser Ala Glu Pro Thr
                 875                 880                 885

 Pro Lys Ala Leu Glu Asn Ser Pro Lys Glu Pro Gly Val Pro Thr
                 890                 895                 900

 Thr Lys Thr Pro Ala Ala Thr Lys Pro Glu Met Thr Thr Thr Ala
                 905                 910                 915

 Lys Asp Lys Thr Thr Glu Arg Asp Leu Arg Thr Thr Pro Glu Thr
                 920                 925                 930

 Thr Thr Ala Ala Pro Lys Met Thr Lys Glu Thr Ala Thr Thr Thr
                 935                 940                 945

 Glu Lys Thr Thr Glu Ser Lys Ile Thr Ala Thr Thr Thr Gln Val
                 950                 955                 960

 Thr Ser Thr Thr Thr Gln Asp Thr Thr Pro Phe Lys Ile Thr Thr
                 965                 970                 975

 Leu Lys Thr Thr Thr Leu Ala Pro Lys Val Thr Thr Thr Lys Lys
                 980                 985                 990

 Thr Ile Thr Thr Thr Glu Ile Met Asn Lys Pro Glu Glu Thr Ala
                 995                1000                1005

 Lys Pro Lys Asp Arg Ala Thr Asn Ser Lys Ala Thr Thr Pro Lys
                1010                1015                1020

 Pro Gln Lys Pro Thr Lys Ala Pro Lys Lys Pro Thr Ser Thr Lys
                1025                1030                1035

 Lys Pro Lys Thr Met Pro Arg Val Arg Lys Pro Lys Thr Thr Pro
                1040                1045                1050

 Thr Pro Arg Lys Met Thr Ser Thr Met Pro Glu Leu Asn Pro Thr
                1055                1060                1065

 Ser Arg Ile Ala Glu Ala Met Leu Gln Thr Thr Thr Arg Pro Asn
                1070                1075                1080

 Gln Thr Pro Asn Ser Lys Leu Val Glu Val Asn Pro Lys Ser Glu
                1085                1090                1095

 Asp Ala Gly Gly Ala Glu Gly Glu Thr Pro His Met Leu Leu Arg
                1100                1105                1110

 Pro His Val Phe Met Pro Glu Val Thr Pro Asp Met Asp Tyr Leu
                1115                1120                1125

 Pro Arg Val Pro Asn Gln Gly Ile Ile Ile Asn Pro Met Leu Ser
                1130                1135                1140

 Asp Glu Thr Asn Ile Cys Asn Gly Lys Pro Val Asp Gly Leu Thr
                1145                1150                1155

 Thr Leu Arg Asn Gly Thr Leu Val Ala Phe Arg Gly His Tyr Phe
                1160                1165                1170

 Trp Met Leu Ser Pro Phe Ser Pro Pro Ser Pro Ala Arg Arg Ile
                1175                1180                1185

 Thr Glu Val Trp Gly Ile Pro Ser Pro Ile Asp Thr Val Phe Thr
                1190                1195                1200

 Arg Cys Asn Cys Glu Gly Lys Thr Phe Phe Phe Lys Asp Ser Gln
                1205                1210                1215

 Tyr Trp Arg Phe Thr Asn Asp Ile Lys Asp Ala Gly Tyr Pro Lys
                1220                1225                1230

 Pro Ile Phe Lys Gly Phe Gly Gly Leu Thr Gly Gln Ile Val Ala
                1235                1240                1245

 Ala Leu Ser Thr Ala Lys Tyr Lys Asn Trp Pro Glu Ser Val Tyr
                1250                1255                1260

 Phe Phe Lys Arg Gly Gly Ser Ile Gln Gln Tyr Ile Tyr Lys Gln
                1265                1270                1275

 Glu Pro Val Gln Lys Cys Pro Gly Arg Arg Pro Ala Leu Asn Tyr
                1280                1285                1290

 Pro Val Tyr Gly Glu Met Thr Gln Val Arg Arg Arg Arg Phe Glu
                1295                1300                1305

 Arg Ala Ile Gly Pro Ser Gln Thr His Thr Ile Arg Ile Gln Tyr
                1310                1315                1320

 Ser Pro Ala Arg Leu Ala Tyr Gln Asp Lys Gly Val Leu His Asn
                1325                1330                1335

 Glu Val Lys Val Ser Ile Leu Trp Arg Gly Leu Pro Asn Val Val
                1340                1345                1350

 Thr Ser Ala Ile Ser Leu Pro Asn Ile Arg Lys Pro Asp Gly Tyr
                1355                1360                1365

 Asp Tyr Tyr Ala Phe Ser Lys Asp Gln Tyr Tyr Asn Ile Asp Val
                1370                1375                1380

 Pro Ser Arg Thr Ala Arg Ala Ile Thr Thr Arg Ser Gly Gln Thr
                1385                1390                1395

 Leu Ser Lys Val Trp Tyr Asn Cys Pro
                1400

<210> 1465
<211> 2337
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 61, 2277
<223> Unknown base

<400> 1465
 cggaaggtgt gagccgcaaa cccagcggag ggcgggaaga aggaggaggc 50

 ctctagggtg ntcgggggac tgggggcccc gccggcagag gtccctcggc 100

 ctcctgactg actgactgcg gccgcctccg gccaggacgc tgggagctgc 150

 ctgcgggaag gtgcggggag cggagccatg gcctccggtg cgtataaccc 200

 gtatatagag ataattgaac aacccaggca gaggggaatg cgttttagat 250

 acaaatgtga agggcgatca gcaggcagca ttccagggga gcacagcaca 300

 gacaacaacc gaacataccc ttctatccag attatgaact attatggaaa 350

 aggaaaagtg agaattacat tagtaacaaa gaatgaccca tataaacctc 400

 atcctcatga tttagttgga aaagactgca gagacggcta ctatgaagca 450

 gaatttggac aagaacgcag acctttgttt ttccaaaatt tgggtattcg 500

 atgtgtgaag aaaaaagaag taaaagaagc tattattaca agaataaagg 550

 caggaatcaa tccattcaat gtccctgaaa aacagctgaa tgatattgaa 600

 gattgtgacc tcaatgtggt gagactgtgt tttcaagttt ttctccctga 650

 tgaacatggt aatttgacga ctgctcttcc tcctgttgtc tcgaacccaa 700

 tttatgacaa ccgtgctcca aatactgcag aattaaggat ttgtcgtgta 750

 aacaagaatt gtggaagtgt cagaggagga gatgaaatat ttctactttg 800

 tgacaaagtt cagaaagatg acatagaagt tcgttttgtg ttgaacgatt 850

 gggaagcaaa aggcatcttt tcacaagctg atgtacaccg tcaagtagcc 900

 attgttttca aaactccacc atattgcaaa gctatcacag aacccgtaac 950

 agtaaaaatg cagttgcgga gaccttctga ccaggaagtt agtgaatcta 1000

 tggattttag atatctgcca gatgaaaaag atacttacgg caataaagca 1050

 aagaaacaaa agacaactct gcttttccag aaactgtgcc aggatcacgt 1100

 agaaacaggg tttcgccatg ttgaccagga tggtcttgaa ctcctgacat 1150

 caggtgatcc acccaccttg gcctcccaaa gtgctgggat tacagttaat 1200

 tttcctgaga gaccaagacc tggtctcctc ggttcaattg gagaaggaag 1250

 atacttcaaa aaagaaccaa acttgttttc tcatgatgca gttgtgagag 1300

 aaatgcctac aggggtttca agtcaagcag aatcctacta tccctcacct 1350

 gggcccatct caagtggatt gtcacatcat gcctcaatgg cacctctgcc 1400

 ttcttcaagc tggtcatcag tggcccaccc caccccacgc tcaggcaata 1450

 caaacccact gagtagtttt tcaacaagga cacttccttc taattcgcaa 1500

 ggtatcccac cattcctgag aatacctgtt gggaatgatt taaatgcttc 1550

 taatgcttgc atttacaaca atgccgatga catagtcgga atggaagcgt 1600

 catccatgcc atcagcagat ttatatggta tttctgatcc caacatgctg 1650

 tctaattgtt ctgtgaatat gatgacaacc agcagtgaca gcatgggaga 1700

 gactgataat ccaagacttc tgagcatgaa tcttgaaaac ccctcatgta 1750

 attcagtgtt agacccaaga gacttgagac agctccatca gatgtcctct 1800

 tccagtatgt cagcaggcgc caattccaat actactgttt ttgtttcaca 1850

 atcagatgca tttgagggat ctgacttcag ttgtgcagat aacagcatga 1900

 taaatgagtc gggaccatca aacagtacta atccaaacag tcatggtttt 1950

 gttcaagata gtcagtattc aggtattggc agtatgcaaa atgagcaatt 2000

 gagtgactcc tttccatatg aattttttca agtataactt gcaagattta 2050

 aatcctttta aatcttgata ccacctatat agatgcagca ttttgtattt 2100

 gtctaactgg ggatataata ctatatttat actgtatata taatactgac 2150

 tgagaatata atactgtatt tgagaatata aaaaactttt ttcagggaag 2200

 aagcatacaa ctttggacat agcgaataca aaattggaag ctgtcataaa 2250

 aagacaactc agaggccagg cgcaggngct cacacctgta atcctagcac 2300

 tttgggaggc caaggcgggt ggatcacttg agaccag 2337

<210> 1466
<211> 619
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 61, 2277
<223> Unknown amino acid

<400> 1466
 Met Ala Ser Gly Ala Tyr Asn Pro Tyr Ile Glu Ile Ile Glu Gln
   1               5                  10                  15

 Pro Arg Gln Arg Gly Met Arg Phe Arg Tyr Lys Cys Glu Gly Arg
                  20                  25                  30

 Ser Ala Gly Ser Ile Pro Gly Glu His Ser Thr Asp Asn Asn Arg
                  35                  40                  45

 Thr Tyr Pro Ser Ile Gln Ile Met Asn Tyr Tyr Gly Lys Gly Lys
                  50                  55                  60

 Val Arg Ile Thr Leu Val Thr Lys Asn Asp Pro Tyr Lys Pro His
                  65                  70                  75

 Pro His Asp Leu Val Gly Lys Asp Cys Arg Asp Gly Tyr Tyr Glu
                  80                  85                  90

 Ala Glu Phe Gly Gln Glu Arg Arg Pro Leu Phe Phe Gln Asn Leu
                  95                 100                 105

 Gly Ile Arg Cys Val Lys Lys Lys Glu Val Lys Glu Ala Ile Ile
                 110                 115                 120

 Thr Arg Ile Lys Ala Gly Ile Asn Pro Phe Asn Val Pro Glu Lys
                 125                 130                 135

 Gln Leu Asn Asp Ile Glu Asp Cys Asp Leu Asn Val Val Arg Leu
                 140                 145                 150

 Cys Phe Gln Val Phe Leu Pro Asp Glu His Gly Asn Leu Thr Thr
                 155                 160                 165

 Ala Leu Pro Pro Val Val Ser Asn Pro Ile Tyr Asp Asn Arg Ala
                 170                 175                 180

 Pro Asn Thr Ala Glu Leu Arg Ile Cys Arg Val Asn Lys Asn Cys
                 185                 190                 195

 Gly Ser Val Arg Gly Gly Asp Glu Ile Phe Leu Leu Cys Asp Lys
                 200                 205                 210

 Val Gln Lys Asp Asp Ile Glu Val Arg Phe Val Leu Asn Asp Trp
                 215                 220                 225

 Glu Ala Lys Gly Ile Phe Ser Gln Ala Asp Val His Arg Gln Val
                 230                 235                 240

 Ala Ile Val Phe Lys Thr Pro Pro Tyr Cys Lys Ala Ile Thr Glu
                 245                 250                 255

 Pro Val Thr Val Lys Met Gln Leu Arg Arg Pro Ser Asp Gln Glu
                 260                 265                 270

 Val Ser Glu Ser Met Asp Phe Arg Tyr Leu Pro Asp Glu Lys Asp
                 275                 280                 285

 Thr Tyr Gly Asn Lys Ala Lys Lys Gln Lys Thr Thr Leu Leu Phe
                 290                 295                 300

 Gln Lys Leu Cys Gln Asp His Val Glu Thr Gly Phe Arg His Val
                 305                 310                 315

 Asp Gln Asp Gly Leu Glu Leu Leu Thr Ser Gly Asp Pro Pro Thr
                 320                 325                 330

 Leu Ala Ser Gln Ser Ala Gly Ile Thr Val Asn Phe Pro Glu Arg
                 335                 340                 345

 Pro Arg Pro Gly Leu Leu Gly Ser Ile Gly Glu Gly Arg Tyr Phe
                 350                 355                 360

 Lys Lys Glu Pro Asn Leu Phe Ser His Asp Ala Val Val Arg Glu
                 365                 370                 375

 Met Pro Thr Gly Val Ser Ser Gln Ala Glu Ser Tyr Tyr Pro Ser
                 380                 385                 390

 Pro Gly Pro Ile Ser Ser Gly Leu Ser His His Ala Ser Met Ala
                 395                 400                 405

 Pro Leu Pro Ser Ser Ser Trp Ser Ser Val Ala His Pro Thr Pro
                 410                 415                 420

 Arg Ser Gly Asn Thr Asn Pro Leu Ser Ser Phe Ser Thr Arg Thr
                 425                 430                 435

 Leu Pro Ser Asn Ser Gln Gly Ile Pro Pro Phe Leu Arg Ile Pro
                 440                 445                 450

 Val Gly Asn Asp Leu Asn Ala Ser Asn Ala Cys Ile Tyr Asn Asn
                 455                 460                 465

 Ala Asp Asp Ile Val Gly Met Glu Ala Ser Ser Met Pro Ser Ala
                 470                 475                 480

 Asp Leu Tyr Gly Ile Ser Asp Pro Asn Met Leu Ser Asn Cys Ser
                 485                 490                 495

 Val Asn Met Met Thr Thr Ser Ser Asp Ser Met Gly Glu Thr Asp
                 500                 505                 510

 Asn Pro Arg Leu Leu Ser Met Asn Leu Glu Asn Pro Ser Cys Asn
                 515                 520                 525

 Ser Val Leu Asp Pro Arg Asp Leu Arg Gln Leu His Gln Met Ser
                 530                 535                 540

 Ser Ser Ser Met Ser Ala Gly Ala Asn Ser Asn Thr Thr Val Phe
                 545                 550                 555

 Val Ser Gln Ser Asp Ala Phe Glu Gly Ser Asp Phe Ser Cys Ala
                 560                 565                 570

 Asp Asn Ser Met Ile Asn Glu Ser Gly Pro Ser Asn Ser Thr Asn
                 575                 580                 585

 Pro Asn Ser His Gly Phe Val Gln Asp Ser Gln Tyr Ser Gly Ile
                 590                 595                 600

 Gly Ser Met Gln Asn Glu Gln Leu Ser Asp Ser Phe Pro Tyr Glu
                 605                 610                 615

 Phe Phe Gln Val


<210> 1467
<211> 347
<212> DNA
<213> Homo sapien

<400> 1467
 cagagtggag cggccgccgg agatgcctga cgcatctgtc tgaggagcgg 50

 tcagtgacgc gatggagcgg gcaagggatc gcttacacct gagacgaact 100

 acagaacagc acgtaccaga ggtggaagtc caagtcaaac gcagaaggac 150

 tgcctcactg agcaaccaag agtgtcagtt gtacccgagg cgttctcagc 200

 agcagcaagt acctgtggtg gatttccagg ctgaactgag gcaggcattc 250

 ttagctgaga caccaagagg tggttaaagc catattggag tagcgaggaa 300

 tctgattcca agcaaaaacc agacaatgta ataaaaatat tattcat 347

<210> 1468
<211> 71
<212> PRT
<213> Homo sapien

<400> 1468
 Met Glu Arg Ala Arg Asp Arg Leu His Leu Arg Arg Thr Thr Glu
   1               5                  10                  15

 Gln His Val Pro Glu Val Glu Val Gln Val Lys Arg Arg Arg Thr
                  20                  25                  30

 Ala Ser Leu Ser Asn Gln Glu Cys Gln Leu Tyr Pro Arg Arg Ser
                  35                  40                  45

 Gln Gln Gln Gln Val Pro Val Val Asp Phe Gln Ala Glu Leu Arg
                  50                  55                  60

 Gln Ala Phe Leu Ala Glu Thr Pro Arg Gly Gly
                  65                  70

<210> 1469
<211> 1054
<212> DNA
<213> Homo sapien

<400> 1469
 gaattccgcg ggaggccacg ggctttccac agcgcggggg aacgggaggc 50

 tgcaggatgg tcaagctgac ggcggagctg atcgagcagg cggcgcagta 100

 caccaacgcg gtgcgcgacc gggagctgga cctccggggg tataaaattc 150

 ccgtcattga aaatctaggt gctacgttag accagtttga tgctattgat 200

 ttttctgaca atgagatcag gaaactggat ggttttcctt tgttgagaag 250

 actgaaaaca ttgttagtga acaacaacag aatatgccgt ataggtgagg 300

 gacttgatca ggctctgccc tgtctgacag aactcattct caccaataat 350

 agtctcgtgg aactgggtga tctggaccct ctggcatctc tcaaatcgct 400

 gacttaccta agtatcctaa gaaatccggt aaccaataag aagcattaca 450

 gattgtatgt gatttataaa gttccgcaag tcagagtact ggatttccag 500

 aaagtgaaac taaaagagcg tcaggaagca gagaaaatgt tcaagggcaa 550

 acggggtgca cagcttgcaa aggatattgc caggagaagc aaaactttta 600

 atccaggtgc tggtttgcca actgacaaaa agagaggtgg gccatctcca 650

 ggggatgtag aagcaatcaa gaatgccata gcaaatgctt caactctggc 700

 tgaagtggag aggctgaagg ggttgctgca gtctggtcag atccctggca 750

 gagaacgcag atcagggccc actgatgatg gtgaagaaga gatggaagaa 800

 gacacagtca caaacgggtc ctgagcagtg aggcagatgt ataataatag 850

 gccctcttgg aacaagtctt gcttttcgaa catggtataa tagccttgtt 900

 tgtgttagca aagtggaatc tatcagcatt gttgaaatgc ttaagactgc 950

 tgctgataat tttgtaatat aagttttgaa atctaaatgt caattttcta 1000

 caaattataa aaataaactc cactctctat gctaaaaaaa aaaaaaagga 1050

 attc 1054

<210> 1470
<211> 255
<212> PRT
<213> Homo sapien

<400> 1470
 Met Val Lys Leu Thr Ala Glu Leu Ile Glu Gln Ala Ala Gln Tyr
   1               5                  10                  15

 Thr Asn Ala Val Arg Asp Arg Glu Leu Asp Leu Arg Gly Tyr Lys
                  20                  25                  30

 Ile Pro Val Ile Glu Asn Leu Gly Ala Thr Leu Asp Gln Phe Asp
                  35                  40                  45

 Ala Ile Asp Phe Ser Asp Asn Glu Ile Arg Lys Leu Asp Gly Phe
                  50                  55                  60

 Pro Leu Leu Arg Arg Leu Lys Thr Leu Leu Val Asn Asn Asn Arg
                  65                  70                  75

 Ile Cys Arg Ile Gly Glu Gly Leu Asp Gln Ala Leu Pro Cys Leu
                  80                  85                  90

 Thr Glu Leu Ile Leu Thr Asn Asn Ser Leu Val Glu Leu Gly Asp
                  95                 100                 105

 Leu Asp Pro Leu Ala Ser Leu Lys Ser Leu Thr Tyr Leu Ser Ile
                 110                 115                 120

 Leu Arg Asn Pro Val Thr Asn Lys Lys His Tyr Arg Leu Tyr Val
                 125                 130                 135

 Ile Tyr Lys Val Pro Gln Val Arg Val Leu Asp Phe Gln Lys Val
                 140                 145                 150

 Lys Leu Lys Glu Arg Gln Glu Ala Glu Lys Met Phe Lys Gly Lys
                 155                 160                 165

 Arg Gly Ala Gln Leu Ala Lys Asp Ile Ala Arg Arg Ser Lys Thr
                 170                 175                 180

 Phe Asn Pro Gly Ala Gly Leu Pro Thr Asp Lys Lys Arg Gly Gly
                 185                 190                 195

 Pro Ser Pro Gly Asp Val Glu Ala Ile Lys Asn Ala Ile Ala Asn
                 200                 205                 210

 Ala Ser Thr Leu Ala Glu Val Glu Arg Leu Lys Gly Leu Leu Gln
                 215                 220                 225

 Ser Gly Gln Ile Pro Gly Arg Glu Arg Arg Ser Gly Pro Thr Asp
                 230                 235                 240

 Asp Gly Glu Glu Glu Met Glu Glu Asp Thr Val Thr Asn Gly Ser
                 245                 250                 255

<210> 1471
<211> 3094
<212> DNA
<213> Homo sapien

<400> 1471
 gtctcggcca tgacacacat ttgacatgcc ctccctcaac ctacttatag 50

 actatttttc ttgctctgca gcatggacca aagagaaatt ctgcagaagt 100

 tcctggatga ggcccaaagc aagaaaatta ctaaagagga gtttgccaat 150

 gaatttctga agctgaaaag gcaatctacc aagtacaagg cagacaaaac 200

 ctatcctaca actgtggctg agaagcccaa gaatatcaag aaaaacagat 250

 ataaggatat tttgccctat gattatagcc gggtagaact atccctgata 300

 acctctgatg aggattccag ctacatcaat gccaacttca ttaagggagt 350

 ttatggaccc aaggcttata ttgccaccca gggtccttta tctacaaccc 400

 tcctggactt ctggaggatg atttgggaat atagtgtcct tatcattggt 450

 atggcatgca tggagtatga aatgggaaag aaaaagtgtg agcgctactg 500

 ggctgagcca gtagagatgc agctggaatt tggccctttc tctgtatcct 550

 gtgaagctga aaaaaggaaa tctgattata taatcaggac tctaaaagtt 600

 aagttcaata gtgaaactcg aactatctac cagtttcatt acaagaattg 650

 gccagaccat gatgtacctt catctataga ccctattctt gagctcatct 700

 gggatgtacg ttgttaccaa gaggatgaca gtgttcccat atgcattcac 750

 tgcagtgctg gctgtggaag gactggtgtt atttgtgcta ttgattatac 800

 atggatgttg ctaaaagatg ggataattcc tgagaacttc agtgttttca 850

 gtttgatccg ggaaatgcgg acacagaggc cttcattagt tcaaacgcag 900

 gaacaatatg aactggtcta caatgctgta ttagaactat ttaagagaca 950

 gatggatgtt atcagagata aacattctgg aacagagagt caagcaaagc 1000

 attgtattcc tgagaaaaat cacactctcc aagcagactc ttattctcct 1050

 aatttaccaa aaagtaccac aaaagcagca aaaatgatga accaacaaag 1100

 gacaaaaatg gaaatcaaag aatcttcttc ctttgacttt aggacttctg 1150

 aaataagtgc aaaagaagag ctagttttgc accctgctaa atcaagcact 1200

 tcttttgact ttctggagct aaattacagt tttgacaaaa atgctgacac 1250

 aaccatgaaa tggcagacaa aggcatttcc aatagttggg gagcctcttc 1300

 agaagcatca aagtttggat ttgggctctc ctttgtttga gggatgttct 1350

 aattctaaac ctgtaaatgc agcaggaaga tattttaatt caaaggtgcc 1400

 aataacacgg accaaatcaa ctccttttga attgatacag cagagagaaa 1450

 ccaaggaggt ggacagcaag gaaaactttt cttatttgga atctcaacca 1500

 catgattctt gttttgtaga gatgcaggct caaaaagtaa tgcatgtttc 1550

 ttcagcagaa ctgaattatt cactgccata tgactctaaa caccaaatac 1600

 gtaatgcctc taatgtaaag caccatgact ctagtgctct tggtgtatat 1650

 tcttacatac ctttagtgga aaatccttat ttttcatcat ggcctccaag 1700

 tggtaccagt tctaagatgt ctcttgattt acctgagaag caagatggaa 1750

 ctgtttttcc ttcttctctg ttgccaacat cctctacatc cctcttctct 1800

 tattacaatt cacatgattc tttatcactg aattctccaa ccaatatttc 1850

 ctcactattg aaccaggagt cagctgtact agcaactgct ccaaggatag 1900

 atgatgaaat cccccctcca cttcctgtat ggacacctga atcatttatt 1950

 gtggttgagg aagctggaga attctcacca aatgttccca aatccttatc 2000

 ctcagctgtg aaggtaaaaa ttggaacatc actggaatgg ggtggaacat 2050

 ctgaaccaaa gaaatttgat gactctgtga tacttagacc aagcaagagt 2100

 gtaaaactcc gaagtcctaa atcagaacta catcaagatc gttcttctcc 2150

 cccacctcct ctcccagaaa gaactctaga gtccttcttt cttgccgatg 2200

 aagattgtat gcaggcccaa tctatagaaa catattctac tagctatcct 2250

 gacaccatgg aaaattcaac atcttcaaaa cagacactga agacttctgg 2300

 aaaaagtttc acaaggagta agagtttgaa aattttgcga aacatgaaaa 2350

 agagtatctg taattcttgc ccaccaaaca agcctgcaga atctgttcag 2400

 tcaaataact ccagctcatt tctgaatttt ggttttgcaa accgtttttc 2450

 aaaacccaaa ggaccaagga atccaccacc aacttggaat atttaataaa 2500

 actccagatt tataataata tgggctgcaa gtacacctgc aaataaaact 2550

 actagaatac tgctagttaa aataagtgct ctatatgcat aatatcaaat 2600

 atgaagatat gctaatgtgt taatagcttt taaaagaaaa gcaaaatgcc 2650

 aataagtgcc agttttgcat tttcatatca tttgcattga gttgaaaact 2700

 gcaaataaaa gtttgtcact tgagcttatg tacagaatgc tatatgagaa 2750

 acacttttag aatggattta tttttcattt ttgccagtta tttttattgt 2800

 cttttacttt tctacataaa cataaacttc aaaaggtttg taagatttgg 2850

 atctcaacta atttctacat tgccagaata tactataaaa agttaaaaaa 2900

 aaaaacttac tttgtgggtt gcaatacaaa ctgctcttga caatgactat 2950

 tccctgacag ttatttttgc ctaaatggag tataccttgt aaatcttccc 3000

 aaatgttgtg gaaaactgga atattaagaa aatgagaaat tatatttatt 3050

 agaataaaat gtgcaaataa tgacaattat ttgaatgtaa caag 3094

<210> 1472
<211> 807
<212> PRT
<213> Homo sapien

<400> 1472
 Met Asp Gln Arg Glu Ile Leu Gln Lys Phe Leu Asp Glu Ala Gln
   1               5                  10                  15

 Ser Lys Lys Ile Thr Lys Glu Glu Phe Ala Asn Glu Phe Leu Lys
                  20                  25                  30

 Leu Lys Arg Gln Ser Thr Lys Tyr Lys Ala Asp Lys Thr Tyr Pro
                  35                  40                  45

 Thr Thr Val Ala Glu Lys Pro Lys Asn Ile Lys Lys Asn Arg Tyr
                  50                  55                  60

 Lys Asp Ile Leu Pro Tyr Asp Tyr Ser Arg Val Glu Leu Ser Leu
                  65                  70                  75

 Ile Thr Ser Asp Glu Asp Ser Ser Tyr Ile Asn Ala Asn Phe Ile
                  80                  85                  90

 Lys Gly Val Tyr Gly Pro Lys Ala Tyr Ile Ala Thr Gln Gly Pro
                  95                 100                 105

 Leu Ser Thr Thr Leu Leu Asp Phe Trp Arg Met Ile Trp Glu Tyr
                 110                 115                 120

 Ser Val Leu Ile Ile Gly Met Ala Cys Met Glu Tyr Glu Met Gly
                 125                 130                 135

 Lys Lys Lys Cys Glu Arg Tyr Trp Ala Glu Pro Val Glu Met Gln
                 140                 145                 150

 Leu Glu Phe Gly Pro Phe Ser Val Ser Cys Glu Ala Glu Lys Arg
                 155                 160                 165

 Lys Ser Asp Tyr Ile Ile Arg Thr Leu Lys Val Lys Phe Asn Ser
                 170                 175                 180

 Glu Thr Arg Thr Ile Tyr Gln Phe His Tyr Lys Asn Trp Pro Asp
                 185                 190                 195

 His Asp Val Pro Ser Ser Ile Asp Pro Ile Leu Glu Leu Ile Trp
                 200                 205                 210

 Asp Val Arg Cys Tyr Gln Glu Asp Asp Ser Val Pro Ile Cys Ile
                 215                 220                 225

 His Cys Ser Ala Gly Cys Gly Arg Thr Gly Val Ile Cys Ala Ile
                 230                 235                 240

 Asp Tyr Thr Trp Met Leu Leu Lys Asp Gly Ile Ile Pro Glu Asn
                 245                 250                 255

 Phe Ser Val Phe Ser Leu Ile Arg Glu Met Arg Thr Gln Arg Pro
                 260                 265                 270

 Ser Leu Val Gln Thr Gln Glu Gln Tyr Glu Leu Val Tyr Asn Ala
                 275                 280                 285

 Val Leu Glu Leu Phe Lys Arg Gln Met Asp Val Ile Arg Asp Lys
                 290                 295                 300

 His Ser Gly Thr Glu Ser Gln Ala Lys His Cys Ile Pro Glu Lys
                 305                 310                 315

 Asn His Thr Leu Gln Ala Asp Ser Tyr Ser Pro Asn Leu Pro Lys
                 320                 325                 330

 Ser Thr Thr Lys Ala Ala Lys Met Met Asn Gln Gln Arg Thr Lys
                 335                 340                 345

 Met Glu Ile Lys Glu Ser Ser Ser Phe Asp Phe Arg Thr Ser Glu
                 350                 355                 360

 Ile Ser Ala Lys Glu Glu Leu Val Leu His Pro Ala Lys Ser Ser
                 365                 370                 375

 Thr Ser Phe Asp Phe Leu Glu Leu Asn Tyr Ser Phe Asp Lys Asn
                 380                 385                 390

 Ala Asp Thr Thr Met Lys Trp Gln Thr Lys Ala Phe Pro Ile Val
                 395                 400                 405

 Gly Glu Pro Leu Gln Lys His Gln Ser Leu Asp Leu Gly Ser Pro
                 410                 415                 420

 Leu Phe Glu Gly Cys Ser Asn Ser Lys Pro Val Asn Ala Ala Gly
                 425                 430                 435

 Arg Tyr Phe Asn Ser Lys Val Pro Ile Thr Arg Thr Lys Ser Thr
                 440                 445                 450

 Pro Phe Glu Leu Ile Gln Gln Arg Glu Thr Lys Glu Val Asp Ser
                 455                 460                 465

 Lys Glu Asn Phe Ser Tyr Leu Glu Ser Gln Pro His Asp Ser Cys
                 470                 475                 480

 Phe Val Glu Met Gln Ala Gln Lys Val Met His Val Ser Ser Ala
                 485                 490                 495

 Glu Leu Asn Tyr Ser Leu Pro Tyr Asp Ser Lys His Gln Ile Arg
                 500                 505                 510

 Asn Ala Ser Asn Val Lys His His Asp Ser Ser Ala Leu Gly Val
                 515                 520                 525

 Tyr Ser Tyr Ile Pro Leu Val Glu Asn Pro Tyr Phe Ser Ser Trp
                 530                 535                 540

 Pro Pro Ser Gly Thr Ser Ser Lys Met Ser Leu Asp Leu Pro Glu
                 545                 550                 555

 Lys Gln Asp Gly Thr Val Phe Pro Ser Ser Leu Leu Pro Thr Ser
                 560                 565                 570

 Ser Thr Ser Leu Phe Ser Tyr Tyr Asn Ser His Asp Ser Leu Ser
                 575                 580                 585

 Leu Asn Ser Pro Thr Asn Ile Ser Ser Leu Leu Asn Gln Glu Ser
                 590                 595                 600

 Ala Val Leu Ala Thr Ala Pro Arg Ile Asp Asp Glu Ile Pro Pro
                 605                 610                 615

 Pro Leu Pro Val Trp Thr Pro Glu Ser Phe Ile Val Val Glu Glu
                 620                 625                 630

 Ala Gly Glu Phe Ser Pro Asn Val Pro Lys Ser Leu Ser Ser Ala
                 635                 640                 645

 Val Lys Val Lys Ile Gly Thr Ser Leu Glu Trp Gly Gly Thr Ser
                 650                 655                 660

 Glu Pro Lys Lys Phe Asp Asp Ser Val Ile Leu Arg Pro Ser Lys
                 665                 670                 675

 Ser Val Lys Leu Arg Ser Pro Lys Ser Glu Leu His Gln Asp Arg
                 680                 685                 690

 Ser Ser Pro Pro Pro Pro Leu Pro Glu Arg Thr Leu Glu Ser Phe
                 695                 700                 705

 Phe Leu Ala Asp Glu Asp Cys Met Gln Ala Gln Ser Ile Glu Thr
                 710                 715                 720

 Tyr Ser Thr Ser Tyr Pro Asp Thr Met Glu Asn Ser Thr Ser Ser
                 725                 730                 735

 Lys Gln Thr Leu Lys Thr Ser Gly Lys Ser Phe Thr Arg Ser Lys
                 740                 745                 750

 Ser Leu Lys Ile Leu Arg Asn Met Lys Lys Ser Ile Cys Asn Ser
                 755                 760                 765

 Cys Pro Pro Asn Lys Pro Ala Glu Ser Val Gln Ser Asn Asn Ser
                 770                 775                 780

 Ser Ser Phe Leu Asn Phe Gly Phe Ala Asn Arg Phe Ser Lys Pro
                 785                 790                 795

 Lys Gly Pro Arg Asn Pro Pro Pro Thr Trp Asn Ile
                 800                 805

<210> 1473
<211> 3629
<212> DNA
<213> Homo sapien

<400> 1473
 agcgggaaga gacgcttggg gctggggctc accggacggg taggtccggc 50

 tctccaggga gaggagctgc ccggccctgg agaaggggcg agtcctgcgc 100

 gagtccccgg gaggcgccgc gcgcttggaa gggacggtcg ggcttccccg 150

 gcccgctgag ggctaggcgg cgggctcccc tcctttccac ctcggcaggg 200

 agggaaggag gggagggaaa agtcccacgg aggaggcaga atggccagtc 250

 gaggggcgct taggcgctgc ctttccccag ggctgcctcg actcctgcac 300

 ctgtcccgag ggctggcctg agacgggact cccggttctc ccgctgcgaa 350

 gcagcgcggc cccccggggc cggggcagcg gcgccggcat gtcgtctggc 400

 accatgaagt tcaatggcta tttgagggtc cgcatcggtg aggcagtggg 450

 gctgcagccc acccgctggt ccctgcgcca ctcgctcttc aagaagggcc 500

 accagctgct ggacccctat ctgacggtga gcgtggacca ggtgcgcgtg 550

 ggccagacca gcaccaagca gaagaccaac aaacccacgt acaacgagga 600

 gttttgcgct aacgtcaccg acggcggcca cctcgagttg gccgtcttcc 650

 acgagacgcc cctgggctac gaccacttcg tggccaactg caccctgcag 700

 ttccaggagc tgctgcgcac gaccggcgcc tcggacacct tcgagggttg 750

 ggtggatctc gagccagagg ggaaagtatt cgtggtaata acccttaccg 800

 ggagtttcac tgaagctact ctccagagag accggatctt caaacatttt 850

 accaggaagc gccaaagggc tatgcgaagg cgagtccacc agatcaatgg 900

 acacaagttc atggccacgt atctgaggca gcccacctac tgctctcact 950

 gcagggagtt tatctgggga gtgtttggga aacagggtta tcagtgccaa 1000

 gtgtgcacct gtgtcgtcca taaacgctgc catcatctaa ttgttacagc 1050

 ctgtacttgc caaaacaata ttaacaaagt ggattcaaag attgcagaac 1100

 agaggttcgg gatcaacatc ccacacaagt tcagcatcca caactacaaa 1150

 gtgccaacat tctgcgatca ctgtggctca ctgctctggg gaataatgcg 1200

 acaaggactt cagtgtaaaa tatgtaaaat gaatgtgcat attcgatgtc 1250

 aagcgaacgt ggcccctaac tgtggggtaa atgcggtgga acttgccaag 1300

 accctggcag ggatgggtct ccaacccgga aatatttctc caacctcgaa 1350

 actcgtttcc agatcgaccc taagacgaca gggaaaggag agcagcaaag 1400

 aaggaaatgg gattggggtt aattcttcca accgacttgg tatcgacaac 1450

 tttgagttca tccgagtgtt ggggaagggg agttttggga aggtgatgct 1500

 tgcaagagta aaagaaacag gagacctcta tgctgtgaag gtgctgaaga 1550

 aggacgtgat tctgcaggat gatgatgtgg aatgcaccat gaccgagaaa 1600

 aggatcctgt ctctggcccg caatcacccc ttcctcactc agttgttctg 1650

 ctgctttcag acccccgatc gtctgttttt tgtgatggag tttgtgaatg 1700

 ggggtgactt gatgttccac attcagaagt ctcgtcgttt tgatgaagca 1750

 cgagctcgct tctatgctgc agaaatcatt tcggctctca tgttcctcca 1800

 tgataaagga atcatctata gagatctgaa actggacaat gtcctgttgg 1850

 accacgaggg tcactgtaaa ctggcagact tcggaatgtg caaggagggg 1900

 atttgcaatg gtgtcaccac ggccacattc tgtggcacgc cagactatat 1950

 cgctccagag atcctccagg aaatgctgta cgggcctgca gtagactggt 2000

 gggcaatggg cgtgttgctc tatgagatgc tctgtggtca cgcgcctttt 2050

 gaggcagaga atgaagatga cctctttgag gccatactga atgatgaggt 2100

 ggtctaccct acctggctcc atgaagatgc cacagggatc ctaaaatctt 2150

 tcatgaccaa gaaccccacc atgcgcttgg gcagcctgac tcagggaggc 2200

 gagcacgcca tcttgagaca tccttttttt aaggaaatcg actgggccca 2250

 gctgaaccat cgccaaatag aaccgccttt cagacccaga atcaaatccc 2300

 gagaagatgt cagtaatttt gaccctgact tcataaagga agagccagtt 2350

 ttaactccaa ttgatgaggg acatcttcca atgattaacc aggatgagtt 2400

 tagaaacttt tcctatgtgt ctccagaatt gcaaccatag ccttatgggg 2450

 agtgagagag agggcacgag aacccaaagg gaatagagat tctccaggaa 2500

 tttcctctat gggaccttcc cagcatcagc cttagaacaa gaaccttacc 2550

 ttcaaggagc aagtgaagaa ctctgtgaag gatggaactt tcagatatca 2600

 actatttaga gtccagaggg agccatggca ctagaaatag ttgataatga 2650

 aatgagattt tatgaagtat accgctccac ctatgagcgt ctgtctctgt 2700

 gggcttggga tgttaacagg agccaaaagg agggaaagtg tgaagaataa 2750

 agtagatctg agaaattctg agccaatcag gcttcttaat tcaagagaca 2800

 aaccaagacg ttctgtcaac tgtgctgtgc tcttctttaa gccaatgaac 2850

 cccaattcct ggcagtctac aagaagtctc ttaatgctaa tgaagaattt 2900

 aaaggtcttt ttaaggaaat gaagggcttt ccaaatagaa tgatttactc 2950

 tgaagaaaca aacaatggta tctctgaaac tcacaaccta aagcccaatc 3000

 ttgaaaatat gttgtgcacc aagacgactg cttcagcttc ttctcttatc 3050

 cttactttct ttaatagata tttattaaac tgtccagtga aaaggtgcca 3100

 caatgcccag tattgtaaac aacaggtttg cattcatgaa gctttcattc 3150

 attctggagt ctactaattt acctgaatgg tgtttgcatt ctgtgaaatg 3200

 cctctccacg ttgcatatgt cacacttttg tctgcacata actctttttt 3250

 cacaagaagg gtcactgcca caacagcaca gtcagcgggt gaattacagg 3300

 tgcctgctgc ctgcctacct gggtaatctg atcttgtctg tatcgccgtg 3350

 tgctcatcac tgaagaattg caggccactc atgtcagtga ccagatttgt 3400

 ggcttataaa cattagcagt ttatttatgt tttaagatgc aaagatgtgt 3450

 gtttgatatt cactttaata attagaaatg gatcttgtaa acagggcata 3500

 tatcaaagat gaccttataa tatgtacccg aatatacagt tcaagaattt 3550

 tgtctgactg gaaataaatg cattttgtag caaaaaaaaa aaaaaaaaaa 3600

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 3629

<210> 1474
<211> 683
<212> PRT
<213> Homo sapien

<400> 1474
 Met Ser Ser Gly Thr Met Lys Phe Asn Gly Tyr Leu Arg Val Arg
   1               5                  10                  15

 Ile Gly Glu Ala Val Gly Leu Gln Pro Thr Arg Trp Ser Leu Arg
                  20                  25                  30

 His Ser Leu Phe Lys Lys Gly His Gln Leu Leu Asp Pro Tyr Leu
                  35                  40                  45

 Thr Val Ser Val Asp Gln Val Arg Val Gly Gln Thr Ser Thr Lys
                  50                  55                  60

 Gln Lys Thr Asn Lys Pro Thr Tyr Asn Glu Glu Phe Cys Ala Asn
                  65                  70                  75

 Val Thr Asp Gly Gly His Leu Glu Leu Ala Val Phe His Glu Thr
                  80                  85                  90

 Pro Leu Gly Tyr Asp His Phe Val Ala Asn Cys Thr Leu Gln Phe
                  95                 100                 105

 Gln Glu Leu Leu Arg Thr Thr Gly Ala Ser Asp Thr Phe Glu Gly
                 110                 115                 120

 Trp Val Asp Leu Glu Pro Glu Gly Lys Val Phe Val Val Ile Thr
                 125                 130                 135

 Leu Thr Gly Ser Phe Thr Glu Ala Thr Leu Gln Arg Asp Arg Ile
                 140                 145                 150

 Phe Lys His Phe Thr Arg Lys Arg Gln Arg Ala Met Arg Arg Arg
                 155                 160                 165

 Val His Gln Ile Asn Gly His Lys Phe Met Ala Thr Tyr Leu Arg
                 170                 175                 180

 Gln Pro Thr Tyr Cys Ser His Cys Arg Glu Phe Ile Trp Gly Val
                 185                 190                 195

 Phe Gly Lys Gln Gly Tyr Gln Cys Gln Val Cys Thr Cys Val Val
                 200                 205                 210

 His Lys Arg Cys His His Leu Ile Val Thr Ala Cys Thr Cys Gln
                 215                 220                 225

 Asn Asn Ile Asn Lys Val Asp Ser Lys Ile Ala Glu Gln Arg Phe
                 230                 235                 240

 Gly Ile Asn Ile Pro His Lys Phe Ser Ile His Asn Tyr Lys Val
                 245                 250                 255

 Pro Thr Phe Cys Asp His Cys Gly Ser Leu Leu Trp Gly Ile Met
                 260                 265                 270

 Arg Gln Gly Leu Gln Cys Lys Ile Cys Lys Met Asn Val His Ile
                 275                 280                 285

 Arg Cys Gln Ala Asn Val Ala Pro Asn Cys Gly Val Asn Ala Val
                 290                 295                 300

 Glu Leu Ala Lys Thr Leu Ala Gly Met Gly Leu Gln Pro Gly Asn
                 305                 310                 315

 Ile Ser Pro Thr Ser Lys Leu Val Ser Arg Ser Thr Leu Arg Arg
                 320                 325                 330

 Gln Gly Lys Glu Ser Ser Lys Glu Gly Asn Gly Ile Gly Val Asn
                 335                 340                 345

 Ser Ser Asn Arg Leu Gly Ile Asp Asn Phe Glu Phe Ile Arg Val
                 350                 355                 360

 Leu Gly Lys Gly Ser Phe Gly Lys Val Met Leu Ala Arg Val Lys
                 365                 370                 375

 Glu Thr Gly Asp Leu Tyr Ala Val Lys Val Leu Lys Lys Asp Val
                 380                 385                 390

 Ile Leu Gln Asp Asp Asp Val Glu Cys Thr Met Thr Glu Lys Arg
                 395                 400                 405

 Ile Leu Ser Leu Ala Arg Asn His Pro Phe Leu Thr Gln Leu Phe
                 410                 415                 420

 Cys Cys Phe Gln Thr Pro Asp Arg Leu Phe Phe Val Met Glu Phe
                 425                 430                 435

 Val Asn Gly Gly Asp Leu Met Phe His Ile Gln Lys Ser Arg Arg
                 440                 445                 450

 Phe Asp Glu Ala Arg Ala Arg Phe Tyr Ala Ala Glu Ile Ile Ser
                 455                 460                 465

 Ala Leu Met Phe Leu His Asp Lys Gly Ile Ile Tyr Arg Asp Leu
                 470                 475                 480

 Lys Leu Asp Asn Val Leu Leu Asp His Glu Gly His Cys Lys Leu
                 485                 490                 495

 Ala Asp Phe Gly Met Cys Lys Glu Gly Ile Cys Asn Gly Val Thr
                 500                 505                 510

 Thr Ala Thr Phe Cys Gly Thr Pro Asp Tyr Ile Ala Pro Glu Ile
                 515                 520                 525

 Leu Gln Glu Met Leu Tyr Gly Pro Ala Val Asp Trp Trp Ala Met
                 530                 535                 540

 Gly Val Leu Leu Tyr Glu Met Leu Cys Gly His Ala Pro Phe Glu
                 545                 550                 555

 Ala Glu Asn Glu Asp Asp Leu Phe Glu Ala Ile Leu Asn Asp Glu
                 560                 565                 570

 Val Val Tyr Pro Thr Trp Leu His Glu Asp Ala Thr Gly Ile Leu
                 575                 580                 585

 Lys Ser Phe Met Thr Lys Asn Pro Thr Met Arg Leu Gly Ser Leu
                 590                 595                 600

 Thr Gln Gly Gly Glu His Ala Ile Leu Arg His Pro Phe Phe Lys
                 605                 610                 615

 Glu Ile Asp Trp Ala Gln Leu Asn His Arg Gln Ile Glu Pro Pro
                 620                 625                 630

 Phe Arg Pro Arg Ile Lys Ser Arg Glu Asp Val Ser Asn Phe Asp
                 635                 640                 645

 Pro Asp Phe Ile Lys Glu Glu Pro Val Leu Thr Pro Ile Asp Glu
                 650                 655                 660

 Gly His Leu Pro Met Ile Asn Gln Asp Glu Phe Arg Asn Phe Ser
                 665                 670                 675

 Tyr Val Ser Pro Glu Leu Gln Pro
                 680

<210> 1475
<211> 3107
<212> DNA
<213> Homo sapien

<400> 1475
 aagcggcagg agcagcgttg gcaccggcga accatggctg ggattttcta 50

 tttcgcccta ttttcgtgtc tcttcgggat ttgcgacgct gtcacaggtt 100

 ccagggtata ccccgcgaat gaagttacct tattggattc cagatctgtt 150

 cagggagaac ttgggtggat agcaagccct ctggaaggag ggtgggagga 200

 agtgagtatc atggatgaaa aaaatacacc aatccgaacc taccaagtgt 250

 gcaatgtgat ggaacccagc cagaataact ggctacgaac tgattggatc 300

 acccgagaag gggctcagag ggtgtatatt gagattaaat tcaccttgag 350

 ggactgcaat agtcttccgg gcgtcatggg gacttgcaag gagacgttta 400

 acctgtacta ctatgaatca gacaacgaca aagagcgttt catcagagag 450

 aaccagtttg tcaaaattga caccattgct gctgatgaga gcttcaccca 500

 agtggacatt ggtgacagaa tcatgaagct gaacaccgag atccgggatg 550

 tagggccatt aagcaaaaag gggttttacc tggcttttca ggatgtgggg 600

 gcctgcatcg ccctggtatc agtccgtgtg ttctataaaa agtgtccact 650

 cacagtccgc aatctggccc agtttcctga caccatcaca ggggctgata 700

 cgtcttccct ggtggaagtt cgaggctcct gtgtcaacaa ctcagaagag 750

 aaagatgtgc caaaaatgta ctgtggggca gatggtgaat ggctggtacc 800

 cattggcaac tgcctatgca acgctgggca tgaggagcgg agcggagaat 850

 gccaagcttg caaaattgga tattacaagg ctctctccac ggatgccacc 900

 tgtgccaagt gcccacccca cagctactct gtctgggaag gagccacctc 950

 gtgcacctgt gaccgaggct ttttcagagc tgacaacgat gctgcctcta 1000

 tgccctgcac ccgtccacca tctgctcccc tgaacttgat ttcaaatgtc 1050

 aacgagacat ctgtgaactt ggaatggagt agccctcaga atacaggtgg 1100

 ccgccaggac atttcctata atgtggtatg caagaaatgt ggagctggtg 1150

 accccagcaa gtgccgaccc tgtggaagtg gggtccacta caccccacag 1200

 cagaatggct tgaagaccac caaagtctcc atcactgacc tcctagctca 1250

 taccaattac acctttgaaa tctgggctgt gaatggagtg tccaaatata 1300

 accctaaccc agaccaatca gtttctgtca ctgtgaccac caaccaagca 1350

 gcaccatcat ccattgcttt ggtccaggct aaagaagtca caagatacag 1400

 tgtggcactg gcttggctgg aaccagatcg gcccaatggg gtaatcctgg 1450

 aatatgaagt caagtattat gagaaggatc agaatgagcg aagctatcgt 1500

 atagttcgga cagctgccag gaacacagat atcaaaggcc tgaaccctct 1550

 cacttcctat gttttccacg tgcgagccag gacagcagct ggctatggag 1600

 acttcagtga gcccttggag gttacaacca acacagtgcc ttcccggatc 1650

 attggagatg gggctaactc cacagtcctt ctggtctctg tctcgggcag 1700

 tgtggtgctg gtggtaattc tcattgcagc ttttgtcatc agccggagac 1750

 ggagtaaata cagtaaagcc aaacaagaag cggatgaaga gaaacatttg 1800

 aatcaaggtg taagaacata tgtggacccc tttacgtacg aagatcccaa 1850

 ccaagcagtg cgagagtttg ccaaagaaat tgacgcatcc tgcattaaga 1900

 ttgaaaaagt tataggagtt ggtgaatttg gtgaggtatg cagtgggcgt 1950

 ctcaaagtgc ctggcaagag agagatctgt gtggctatca agactctgaa 2000

 agctggttat acagacaaac agaggagaga cttcctgagt gaggccagca 2050

 tcatgggaca gtttgaccat ccgaacatca ttcacttgga aggcgtggtc 2100

 actaaatgta aaccagtaat gatcataaca gagtacatgg agaatggctc 2150

 cttggatgca ttcctcagga aaaatgatgg cagatttaca gtcattcagc 2200

 tggtgggcat gcttcgtggc attgggtctg ggatgaagta tttatctgat 2250

 atgagctatg tgcatcgtga tctggccgca cggaacatcc tggtgaacag 2300

 caacttggtc tgcaaagtgt ctgattttgg catgtcccga gtgcttgagg 2350

 atgatccgga agcagcttac accaccaggg gtggcaagat tcctatccgg 2400

 tggactgcgc cagaagcaat tgcctatcgt aaattcacat cagcaagtga 2450

 tgtatggagc tatggaatcg ttatgtggga agtgatgtcg tacggggaga 2500

 ggccctattg ggatatgtcc aatcaagatg tgattaaagc cattgaggaa 2550

 ggctatcggt taccccctcc aatggactgc cccattgcgc tccaccagct 2600

 gatgctagac tgctggcaga aggagaggag cgacaggcct aaatttgggc 2650

 agattgtcaa catgttggac aaactcatcc gcaaccccaa cagcttgaag 2700

 aggacaggga cggagagctc cagacctaac actgccttgt tggatccaag 2750

 ctcccctgaa ttctctgctg tggtatcagt gggcgattgg ctccaggcca 2800

 ttaaaatgga ccggtataag gataacttca cagctgctgg ttataccaca 2850

 ctagaggctg tggtgcacgt gaaccaggag gacctggcaa gaattggtat 2900

 cacagccatc acgcaccaga ataagatttt gagcagtgtc caggcaatgc 2950

 gaacccaaat gcagcagatg cacggcagaa tggttcccgt ctgagccagt 3000

 actgaataaa ctcaaaactc ttgaaattag tttacctcat ccatgcactt 3050

 taattgaaga actgcacttt ttttacttcg tcttcgccct ctgaaattaa 3100

 agaaatg 3107

<210> 1476
<211> 986
<212> PRT
<213> Homo sapien

<400> 1476
 Met Ala Gly Ile Phe Tyr Phe Ala Leu Phe Ser Cys Leu Phe Gly
   1               5                  10                  15

 Ile Cys Asp Ala Val Thr Gly Ser Arg Val Tyr Pro Ala Asn Glu
                  20                  25                  30

 Val Thr Leu Leu Asp Ser Arg Ser Val Gln Gly Glu Leu Gly Trp
                  35                  40                  45

 Ile Ala Ser Pro Leu Glu Gly Gly Trp Glu Glu Val Ser Ile Met
                  50                  55                  60

 Asp Glu Lys Asn Thr Pro Ile Arg Thr Tyr Gln Val Cys Asn Val
                  65                  70                  75

 Met Glu Pro Ser Gln Asn Asn Trp Leu Arg Thr Asp Trp Ile Thr
                  80                  85                  90

 Arg Glu Gly Ala Gln Arg Val Tyr Ile Glu Ile Lys Phe Thr Leu
                  95                 100                 105

 Arg Asp Cys Asn Ser Leu Pro Gly Val Met Gly Thr Cys Lys Glu
                 110                 115                 120

 Thr Phe Asn Leu Tyr Tyr Tyr Glu Ser Asp Asn Asp Lys Glu Arg
                 125                 130                 135

 Phe Ile Arg Glu Asn Gln Phe Val Lys Ile Asp Thr Ile Ala Ala
                 140                 145                 150

 Asp Glu Ser Phe Thr Gln Val Asp Ile Gly Asp Arg Ile Met Lys
                 155                 160                 165

 Leu Asn Thr Glu Ile Arg Asp Val Gly Pro Leu Ser Lys Lys Gly
                 170                 175                 180

 Phe Tyr Leu Ala Phe Gln Asp Val Gly Ala Cys Ile Ala Leu Val
                 185                 190                 195

 Ser Val Arg Val Phe Tyr Lys Lys Cys Pro Leu Thr Val Arg Asn
                 200                 205                 210

 Leu Ala Gln Phe Pro Asp Thr Ile Thr Gly Ala Asp Thr Ser Ser
                 215                 220                 225

 Leu Val Glu Val Arg Gly Ser Cys Val Asn Asn Ser Glu Glu Lys
                 230                 235                 240

 Asp Val Pro Lys Met Tyr Cys Gly Ala Asp Gly Glu Trp Leu Val
                 245                 250                 255

 Pro Ile Gly Asn Cys Leu Cys Asn Ala Gly His Glu Glu Arg Ser
                 260                 265                 270

 Gly Glu Cys Gln Ala Cys Lys Ile Gly Tyr Tyr Lys Ala Leu Ser
                 275                 280                 285

 Thr Asp Ala Thr Cys Ala Lys Cys Pro Pro His Ser Tyr Ser Val
                 290                 295                 300

 Trp Glu Gly Ala Thr Ser Cys Thr Cys Asp Arg Gly Phe Phe Arg
                 305                 310                 315

 Ala Asp Asn Asp Ala Ala Ser Met Pro Cys Thr Arg Pro Pro Ser
                 320                 325                 330

 Ala Pro Leu Asn Leu Ile Ser Asn Val Asn Glu Thr Ser Val Asn
                 335                 340                 345

 Leu Glu Trp Ser Ser Pro Gln Asn Thr Gly Gly Arg Gln Asp Ile
                 350                 355                 360

 Ser Tyr Asn Val Val Cys Lys Lys Cys Gly Ala Gly Asp Pro Ser
                 365                 370                 375

 Lys Cys Arg Pro Cys Gly Ser Gly Val His Tyr Thr Pro Gln Gln
                 380                 385                 390

 Asn Gly Leu Lys Thr Thr Lys Val Ser Ile Thr Asp Leu Leu Ala
                 395                 400                 405

 His Thr Asn Tyr Thr Phe Glu Ile Trp Ala Val Asn Gly Val Ser
                 410                 415                 420

 Lys Tyr Asn Pro Asn Pro Asp Gln Ser Val Ser Val Thr Val Thr
                 425                 430                 435

 Thr Asn Gln Ala Ala Pro Ser Ser Ile Ala Leu Val Gln Ala Lys
                 440                 445                 450

 Glu Val Thr Arg Tyr Ser Val Ala Leu Ala Trp Leu Glu Pro Asp
                 455                 460                 465

 Arg Pro Asn Gly Val Ile Leu Glu Tyr Glu Val Lys Tyr Tyr Glu
                 470                 475                 480

 Lys Asp Gln Asn Glu Arg Ser Tyr Arg Ile Val Arg Thr Ala Ala
                 485                 490                 495

 Arg Asn Thr Asp Ile Lys Gly Leu Asn Pro Leu Thr Ser Tyr Val
                 500                 505                 510

 Phe His Val Arg Ala Arg Thr Ala Ala Gly Tyr Gly Asp Phe Ser
                 515                 520                 525

 Glu Pro Leu Glu Val Thr Thr Asn Thr Val Pro Ser Arg Ile Ile
                 530                 535                 540

 Gly Asp Gly Ala Asn Ser Thr Val Leu Leu Val Ser Val Ser Gly
                 545                 550                 555

 Ser Val Val Leu Val Val Ile Leu Ile Ala Ala Phe Val Ile Ser
                 560                 565                 570

 Arg Arg Arg Ser Lys Tyr Ser Lys Ala Lys Gln Glu Ala Asp Glu
                 575                 580                 585

 Glu Lys His Leu Asn Gln Gly Val Arg Thr Tyr Val Asp Pro Phe
                 590                 595                 600

 Thr Tyr Glu Asp Pro Asn Gln Ala Val Arg Glu Phe Ala Lys Glu
                 605                 610                 615

 Ile Asp Ala Ser Cys Ile Lys Ile Glu Lys Val Ile Gly Val Gly
                 620                 625                 630

 Glu Phe Gly Glu Val Cys Ser Gly Arg Leu Lys Val Pro Gly Lys
                 635                 640                 645

 Arg Glu Ile Cys Val Ala Ile Lys Thr Leu Lys Ala Gly Tyr Thr
                 650                 655                 660

 Asp Lys Gln Arg Arg Asp Phe Leu Ser Glu Ala Ser Ile Met Gly
                 665                 670                 675

 Gln Phe Asp His Pro Asn Ile Ile His Leu Glu Gly Val Val Thr
                 680                 685                 690

 Lys Cys Lys Pro Val Met Ile Ile Thr Glu Tyr Met Glu Asn Gly
                 695                 700                 705

 Ser Leu Asp Ala Phe Leu Arg Lys Asn Asp Gly Arg Phe Thr Val
                 710                 715                 720

 Ile Gln Leu Val Gly Met Leu Arg Gly Ile Gly Ser Gly Met Lys
                 725                 730                 735

 Tyr Leu Ser Asp Met Ser Tyr Val His Arg Asp Leu Ala Ala Arg
                 740                 745                 750

 Asn Ile Leu Val Asn Ser Asn Leu Val Cys Lys Val Ser Asp Phe
                 755                 760                 765

 Gly Met Ser Arg Val Leu Glu Asp Asp Pro Glu Ala Ala Tyr Thr
                 770                 775                 780

 Thr Arg Gly Gly Lys Ile Pro Ile Arg Trp Thr Ala Pro Glu Ala
                 785                 790                 795

 Ile Ala Tyr Arg Lys Phe Thr Ser Ala Ser Asp Val Trp Ser Tyr
                 800                 805                 810

 Gly Ile Val Met Trp Glu Val Met Ser Tyr Gly Glu Arg Pro Tyr
                 815                 820                 825

 Trp Asp Met Ser Asn Gln Asp Val Ile Lys Ala Ile Glu Glu Gly
                 830                 835                 840

 Tyr Arg Leu Pro Pro Pro Met Asp Cys Pro Ile Ala Leu His Gln
                 845                 850                 855

 Leu Met Leu Asp Cys Trp Gln Lys Glu Arg Ser Asp Arg Pro Lys
                 860                 865                 870

 Phe Gly Gln Ile Val Asn Met Leu Asp Lys Leu Ile Arg Asn Pro
                 875                 880                 885

 Asn Ser Leu Lys Arg Thr Gly Thr Glu Ser Ser Arg Pro Asn Thr
                 890                 895                 900

 Ala Leu Leu Asp Pro Ser Ser Pro Glu Phe Ser Ala Val Val Ser
                 905                 910                 915

 Val Gly Asp Trp Leu Gln Ala Ile Lys Met Asp Arg Tyr Lys Asp
                 920                 925                 930

 Asn Phe Thr Ala Ala Gly Tyr Thr Thr Leu Glu Ala Val Val His
                 935                 940                 945

 Val Asn Gln Glu Asp Leu Ala Arg Ile Gly Ile Thr Ala Ile Thr
                 950                 955                 960

 His Gln Asn Lys Ile Leu Ser Ser Val Gln Ala Met Arg Thr Gln
                 965                 970                 975

 Met Gln Gln Met His Gly Arg Met Val Pro Val
                 980                 985

<210> 1477
<211> 4289
<212> DNA
<213> Homo sapien

<400> 1477
 gatcaatact gaggccgcgt cgaccccctt gagccgagac ccccccccag 50

 cccagccccc accccacccc ccgcacacgc cccacccccc ccacgaccca 100

 gcctcatacc gcaccagctg aggcacccaa gaggattacc ccctggggcc 150

 ctctcccgcc ccccaaaaaa gagaagatcc cctctcctgg cccatccctt 200

 cccttcttcc ctcccccctc cccccgaact ttccctctcg catgcttttc 250

 ccctgcacca cggatcgcct ctcggatgcc gcttgcctgg aagctgcgtt 300

 aggagcgagc ggcggcggtg gcggcggtgg cggcggcggc ggcagctcgg 350

 gagtgctatg accggcaaac tcgccgagaa gctgccggtg accatgagca 400

 gtttgctaaa ccaactgcct gacaatctgt accccgagga gatccccagc 450

 gcgctcaacc tcttctccgg cagcagcgac tcggtagtcc attacaatca 500

 gatggctaca gagaatgtaa tggacatcgg tctgaccaac gagaagccca 550

 acccggaact ctcttactcc ggctccttcc agccagcccc cgggaacaag 600

 accgtgacct acttgggaaa gttcgccttc gactcccctt ccaactggtg 650

 ccaggacaac atcattagcc tcatgagcgc cggcatcttg ggggtgcccc 700

 cggcttcagg ggcgctaagc acgcagacgt ccacggccag catggtgcag 750

 ccaccgcagg gtgacgtgga ggccatgtat cccgcgctac ccccctactc 800

 caactgcggc gacctctact cagagcccgt gtctttccac gacccccagg 850

 gcaatcccgg gctcgcctat tccccccagg attaccaatc ggccaagccg 900

 gcgttggaca gcaatctctt ccccatgatt cctgactaca acctctacca 950

 ccaccccaac gacatgggct ccattccgga gcacaagccc ttccagggca 1000

 tggaccccat ccgggtcaac ccgcccccta ctacccctct ggagaccatc 1050

 aaggcattca aagacaagca gatccacccg ggctttggca gcctgcccca 1100

 gccgccgctc accctcaagc ccatccggcc ccgcaagtac cccaaccggc 1150

 ctagcaagac accgctccac gaacggcccc acgcgtgccc ggccgagggc 1200

 tgcgaccgcc gtttcagccg ttcggacgag ctgacccggc acctgcgcat 1250

 ccacacgggc cacaagccct tccagtgccg gatctgcatg cggagcttca 1300

 gccgcagcga ccacctcacc actcacatcc gcactcatac gggcgagaag 1350

 ccctttgcct gcgagttctg cgggcgcaag tttgcgcgca gcgacgagcg 1400

 caagcgccac gccaagatcc acctcaagca aaaggagaag aaggcggaga 1450

 agggcggtgc accctctgca tcctcggcgc cccccgtgtc gctggccccc 1500

 gtggtcacca cctgcgcctg aggatcgggc ccccagatcc ccacttttcc 1550

 cctccagtgc ctcccggctg ctagcctgaa agcagcggga aagccagcca 1600

 cggaggcgta ggggccgcgc cctggcctct ccatggacgt gcggcccctt 1650

 gcttcccctt cgatgccccc ggttcccaac ctttcacgcc ggccagcggt 1700

 caggggccag ggctggaggc gccttcccct cgcggtcccc cacttagcca 1750

 aggcgtgggg gcggaaaggt ggcgtctagc ccgctttgtt cagttcggat 1800

 cgccttgatc caggggccgc cgggccgcgc caaggacctg caagggactg 1850

 aaggcggagc ccatccaacc ctcgcccgac ccaaacacct cattgtttcc 1900

 cccacgtctc cctctatacc ccctcgaaga ctcgagaggg ggagggggta 1950

 aggagcgcac caaagcgcag agcttgctgc ccgccgcacg cacgcgcgcc 2000

 tgcgtgcggg gatgcgcgcg agtgtgtgcg tgctcgcgtg tgtgtgtatg 2050

 tgtgtgtgtg agtgtgtgtg tgtgcgcgcg cgcaagcgtg tgtgtttaag 2100

 actcttgagc tgaactgggc tgtgtttacc ccaaactctt ccccacctcg 2150

 ggtccccaag ccgctgggag atgtcccatg ctgggggtcc gcacgtggct 2200

 ggaggaggtg gtcttccatc cgctctgaaa tcatgtttct tagagaaatg 2250

 cctcggatgc cgccgacgcg gtgctgctgc cgccgcttcg ggtttggccc 2300

 ctcagaaccc ctccttttct gagcgcttcc ctcttaggcc tcagggcagt 2350

 ttgatctgtg gggagaaaga gcagccatcg ctgagcctgc cttttaaaat 2400

 atatgtgtat ttccttagcc ccactctaag aaatctatgt tcctgagttt 2450

 gccccctgcc ctcccactcc ttcccctttt cccctctaaa ccttctccca 2500

 tctctttcaa aatcttttcc cagaaaggca ggcttcaacc agccactcca 2550

 gctttgtgtc ttctctcaat tacatagcaa tttctccttc ccaccatcat 2600

 ggggaagctg gctctgcttt tgccctttgt catcaccaac acaacagata 2650

 gaatttaaat ataagtatat ggtgtgcgtg tgtatgtatg tgtatgtata 2700

 tgcatgcatg tgtataaaga tgcacatgcg tacatataca taacatacac 2750

 acaatatgta ttcctagcaa aataaaatct ctaaggtact tggttatcca 2800

 gtgcagtgca ccggaataaa gagaatttgt aggcgtatac agctttaaat 2850

 gatttatttt ttatgaaaat gttaactgat gagattatat ctacatacgt 2900

 gtgttatgtg tgtggatata gatgcacaca tatctgtaca tatacatgtg 2950

 agtgtacata tatacacata tacacatcta tgtatggata tgtgtgtata 3000

 cacatataca catctctgtc caaaatttcc tcaaagatat ggggattttt 3050

 tcatgaatcc atgtggatga atgaggtgtc tcctttccat acccagtctc 3100

 accttctccc caccctacct cacctcttct caggcacccc tcttccccag 3150

 ctgtcctgcc agcccttctc gtacagggtg gctcctttga agtggagtaa 3200

 tagggaaggt tgctctctgc cacagcttgc agcatggtct tgactgaatg 3250

 tactgttcct gttagcgtta cttctcctgt ggtcagtaag ttgcccagag 3300

 agaaggaaca aaggtctgga gtttacagaa tgtctgtttt taaagtcact 3350

 ttatgcgttt tccacttttt tcttttttaa gaaaaagaag taccattttt 3400

 gttttgtttt gttttgattt ttggtggtgg ataaataata ctaaaaggac 3450

 tctagtggaa aggggggata tcgaagagca gggggttgtg aatttccagg 3500

 tacttggact ttttgtagaa gtagagagaa gaagatgaag tttgccagga 3550

 gggcccatat tttttcagct gaagggtaaa atctttcttt gcagagacag 3600

 tattttgctg aatacttttt ataatgtgat gattattaaa aaagcaaaaa 3650

 ttttggtcac ttccaagcta gaaggaggaa tcagataccc tttaatattt 3700

 tttcctcgct ccttctggta tatgcatgtc actgcatgat aattgagttt 3750

 tcctttgttt taataaaact gttctcagac attaagctaa actaagagaa 3800

 aaataacttt gttgccaaaa ggttgtgcta tccagatttt ttatatgtct 3850

 gcatgtttaa aaaaaaaaaa gcaacaaaag aaaatgcact ctaacttatg 3900

 tgaactgaga gaaaaaaatc aggttttaaa caggaaaacc tatggggaat 3950

 gatatttttt gaaagacttt tgtataaagt tgagtactta gaaaaaagac 4000

 aaaccagatg taatatattt tgtggatgtt tttatttctt ggatttatag 4050

 taccttatac taaggttaaa aaaatatgct tgatattgtg aaaaggtgaa 4100

 attcttcacc aacatttcat ttgctccttt gtcatattgt aatgccaata 4150

 taatatagtt aatgaaaaca gcatttttaa aaaccgaaat attgaaatgg 4200

 tgtaatgttg taccatttgc actgtgagca aatgctaata cagtaaatat 4250

 attgtgtttg ctgacaatca aaaaaaaaaa aaaaaaaaa 4289

<210> 1478
<211> 387
<212> PRT
<213> Homo sapien

<400> 1478
 Met Thr Gly Lys Leu Ala Glu Lys Leu Pro Val Thr Met Ser Ser
   1               5                  10                  15

 Leu Leu Asn Gln Leu Pro Asp Asn Leu Tyr Pro Glu Glu Ile Pro
                  20                  25                  30

 Ser Ala Leu Asn Leu Phe Ser Gly Ser Ser Asp Ser Val Val His
                  35                  40                  45

 Tyr Asn Gln Met Ala Thr Glu Asn Val Met Asp Ile Gly Leu Thr
                  50                  55                  60

 Asn Glu Lys Pro Asn Pro Glu Leu Ser Tyr Ser Gly Ser Phe Gln
                  65                  70                  75

 Pro Ala Pro Gly Asn Lys Thr Val Thr Tyr Leu Gly Lys Phe Ala
                  80                  85                  90

 Phe Asp Ser Pro Ser Asn Trp Cys Gln Asp Asn Ile Ile Ser Leu
                  95                 100                 105

 Met Ser Ala Gly Ile Leu Gly Val Pro Pro Ala Ser Gly Ala Leu
                 110                 115                 120

 Ser Thr Gln Thr Ser Thr Ala Ser Met Val Gln Pro Pro Gln Gly
                 125                 130                 135

 Asp Val Glu Ala Met Tyr Pro Ala Leu Pro Pro Tyr Ser Asn Cys
                 140                 145                 150

 Gly Asp Leu Tyr Ser Glu Pro Val Ser Phe His Asp Pro Gln Gly
                 155                 160                 165

 Asn Pro Gly Leu Ala Tyr Ser Pro Gln Asp Tyr Gln Ser Ala Lys
                 170                 175                 180

 Pro Ala Leu Asp Ser Asn Leu Phe Pro Met Ile Pro Asp Tyr Asn
                 185                 190                 195

 Leu Tyr His His Pro Asn Asp Met Gly Ser Ile Pro Glu His Lys
                 200                 205                 210

 Pro Phe Gln Gly Met Asp Pro Ile Arg Val Asn Pro Pro Pro Thr
                 215                 220                 225

 Thr Pro Leu Glu Thr Ile Lys Ala Phe Lys Asp Lys Gln Ile His
                 230                 235                 240

 Pro Gly Phe Gly Ser Leu Pro Gln Pro Pro Leu Thr Leu Lys Pro
                 245                 250                 255

 Ile Arg Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Leu
                 260                 265                 270

 His Glu Arg Pro His Ala Cys Pro Ala Glu Gly Cys Asp Arg Arg
                 275                 280                 285

 Phe Ser Arg Ser Asp Glu Leu Thr Arg His Leu Arg Ile His Thr
                 290                 295                 300

 Gly His Lys Pro Phe Gln Cys Arg Ile Cys Met Arg Ser Phe Ser
                 305                 310                 315

 Arg Ser Asp His Leu Thr Thr His Ile Arg Thr His Thr Gly Glu
                 320                 325                 330

 Lys Pro Phe Ala Cys Glu Phe Cys Gly Arg Lys Phe Ala Arg Ser
                 335                 340                 345

 Asp Glu Arg Lys Arg His Ala Lys Ile His Leu Lys Gln Lys Glu
                 350                 355                 360

 Lys Lys Ala Glu Lys Gly Gly Ala Pro Ser Ala Ser Ser Ala Pro
                 365                 370                 375

 Pro Val Ser Leu Ala Pro Val Val Thr Thr Cys Ala
                 380                 385

<210> 1479
<211> 2761
<212> DNA
<213> Homo sapien

<400> 1479
 agaggacgcc cggtgaaggg gctccagcct ggcagtttct gcgtgttagc 50

 atttctagaa tagagtgggt gggaactgac ccaagtaaag tcccagagac 100

 tcgaacactg acgcacagga aagcctcaag tgggaggaga aatgcaaatc 150

 ccctactgat gatggcgtca gcggctttct cctagggact gtgaggggcg 200

 cttctgactt tggacttgag cactgcctgg gacctgtgct gagagagcgc 250

 tagcatgtct cagtggaatc aagtccaaca gttagaaatc aagtttttgg 300

 agcaggtgga tcaattctat gatgacaact ttcccatgga aattcggcat 350

 ctgttggccc aatggattga aaatcaagac tgggaggcag cttctaacaa 400

 tgaaaccatg gcaacgattc ttcttcaaaa cttgttaata caactggatg 450

 aacagttagg tcgtgtttcc aaagagaaaa acctactctt gatacacaat 500

 ctaaaaagaa ttaggaaggt ccttcaggga aaatttcatg gaaatccaat 550

 gcatgtagct gtggttattt caaactgttt aagggaagag aggagaatat 600

 tggctgcagc caacatgcct gtccaggggc ctctagagaa atccttacaa 650

 agttcttcag tttcagaaag acagaggaat gtggagcaca aagtggctgc 700

 cattaaaaac agtgtgcaga tgacagaaca agataccaaa tacttagaag 750

 atctgcaaga cgaatttgac tacaggtata aaacaattca gacaatggat 800

 cagagtgaca agaatagtgc catggtgaat caggaagttt tgacactgca 850

 ggaaatgctt aacagcctcg atttcaagag aaaggaggct ctcagtaaaa 900

 tgacccaaat catccatgag acagacctgt taatgaacac catgctcata 950

 gaagagctgc aagactggaa gcggcggcag caaatcgcct gcatcggggg 1000

 tccactccac aatgggctcg accagcttca gaactgcttt acactattgg 1050

 cagaaagtct tttccaactg agaaggcaat tggagaaact agaggagcaa 1100

 tctaccaaaa tgacatatga aggtgatccc attccaatgc aaagaactca 1150

 catgctagaa agagtcacct tcttgatcta caaccttttc aagaactcat 1200

 ttgtggttga gcgacagcca tgtatgccaa cccaccctca gaggccgttg 1250

 gtacttaaaa ccctaattca gttcactgta aaactaaggc tactaataaa 1300

 attgccagaa ctaaactatc aggtaaaggt taaggcatca attgacaaga 1350

 atgtttcaac tctaagcaac cgaagatttg tactttgtgg aactaatgtc 1400

 aaagccatgt ctattgaaga atcttccaat gggagtctct cagtagaatt 1450

 tcgacatttg caaccaaagg aaatgaagtc cagtgctgga ggtaaaggaa 1500

 atgagggctg tcacatggtg actgaagaac ttcattccat aacgtttgaa 1550

 acacagatct gcctctatgg cctgaccata gatttggaga ccagctcatt 1600

 gcctgtggtg atgatttcca atgtcagtca gttacctaat gcttgggcat 1650

 ccatcatttg gtacaacgtg tcaaccaacg attcccagaa cttggttttc 1700

 tttaataatc ctccacctgc cacattgagt caactactgg aggtgatgag 1750

 ctggcagttt tcatcgtacg ttggtcgtgg tcttaactca gatcaactcc 1800

 atatgctggc agagaagctt acagtccaat ctagctacag tgatggtcac 1850

 ctcacctggg ccaagttctg caaggaacat ttacctggta aatcatttac 1900

 cttttggaca tggcttgaag caatattgga tctaattaag aaacacattc 1950

 ttcccctttg gattgatggg tatgtcatgg gctttgttag caaagagaag 2000

 gaacggctgt tgctaaagga taaaatgcct ggcacctttt tattaagatt 2050

 cagtgaaagc catctcggag gaataacttt cacctgggtg gaccattctg 2100

 aaagtgggga agtgagattc cactctgtag aaccctacaa taaaggccgg 2150

 ttgtctgctc tgccattcgc tgacatcctg cgagactaca aagttattat 2200

 ggctgaaaac attcctgaaa accctctgaa gtacctatat cctgacattc 2250

 ccaaagacaa agccttcggt aaacactaca gctctcagcc ttgcgaagtt 2300

 tcaagaccaa cagaaagggg tgacaaaggt tatgttcctt ctgtttttat 2350

 ccccatctca acaatccgaa gtgattcaac agagccacat tctccatcag 2400

 accttcttcc catgtctcca agtgtgtatg cggtgttgag agaaaacctg 2450

 agtcccacaa caattgaaac tgcaatgaag tctccttatt ctgctgaatg 2500

 acaggataaa ctctgacgca ccaagaaagg aagcaaatga aaaagtttaa 2550

 agactgttct ttgcccaata accacatttt atttcttcag ctttgtaaat 2600

 accaggttct aggaaatgtt tgacatctga agctctcttc acactcccgt 2650

 ggcactcctc aattgggagt gttgtgactg aaatgcttga aaccaaagct 2700

 tcagataaac ttgcaagata agacaacttt aagaaaccag tgttaataac 2750

 aatattaaca g 2761

<210> 1480
<211> 748
<212> PRT
<213> Homo sapien

<400> 1480
 Met Ser Gln Trp Asn Gln Val Gln Gln Leu Glu Ile Lys Phe Leu
   1               5                  10                  15

 Glu Gln Val Asp Gln Phe Tyr Asp Asp Asn Phe Pro Met Glu Ile
                  20                  25                  30

 Arg His Leu Leu Ala Gln Trp Ile Glu Asn Gln Asp Trp Glu Ala
                  35                  40                  45

 Ala Ser Asn Asn Glu Thr Met Ala Thr Ile Leu Leu Gln Asn Leu
                  50                  55                  60

 Leu Ile Gln Leu Asp Glu Gln Leu Gly Arg Val Ser Lys Glu Lys
                  65                  70                  75

 Asn Leu Leu Leu Ile His Asn Leu Lys Arg Ile Arg Lys Val Leu
                  80                  85                  90

 Gln Gly Lys Phe His Gly Asn Pro Met His Val Ala Val Val Ile
                  95                 100                 105

 Ser Asn Cys Leu Arg Glu Glu Arg Arg Ile Leu Ala Ala Ala Asn
                 110                 115                 120

 Met Pro Val Gln Gly Pro Leu Glu Lys Ser Leu Gln Ser Ser Ser
                 125                 130                 135

 Val Ser Glu Arg Gln Arg Asn Val Glu His Lys Val Ala Ala Ile
                 140                 145                 150

 Lys Asn Ser Val Gln Met Thr Glu Gln Asp Thr Lys Tyr Leu Glu
                 155                 160                 165

 Asp Leu Gln Asp Glu Phe Asp Tyr Arg Tyr Lys Thr Ile Gln Thr
                 170                 175                 180

 Met Asp Gln Ser Asp Lys Asn Ser Ala Met Val Asn Gln Glu Val
                 185                 190                 195

 Leu Thr Leu Gln Glu Met Leu Asn Ser Leu Asp Phe Lys Arg Lys
                 200                 205                 210

 Glu Ala Leu Ser Lys Met Thr Gln Ile Ile His Glu Thr Asp Leu
                 215                 220                 225

 Leu Met Asn Thr Met Leu Ile Glu Glu Leu Gln Asp Trp Lys Arg
                 230                 235                 240

 Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro Leu His Asn Gly Leu
                 245                 250                 255

 Asp Gln Leu Gln Asn Cys Phe Thr Leu Leu Ala Glu Ser Leu Phe
                 260                 265                 270

 Gln Leu Arg Arg Gln Leu Glu Lys Leu Glu Glu Gln Ser Thr Lys
                 275                 280                 285

 Met Thr Tyr Glu Gly Asp Pro Ile Pro Met Gln Arg Thr His Met
                 290                 295                 300

 Leu Glu Arg Val Thr Phe Leu Ile Tyr Asn Leu Phe Lys Asn Ser
                 305                 310                 315

 Phe Val Val Glu Arg Gln Pro Cys Met Pro Thr His Pro Gln Arg
                 320                 325                 330

 Pro Leu Val Leu Lys Thr Leu Ile Gln Phe Thr Val Lys Leu Arg
                 335                 340                 345

 Leu Leu Ile Lys Leu Pro Glu Leu Asn Tyr Gln Val Lys Val Lys
                 350                 355                 360

 Ala Ser Ile Asp Lys Asn Val Ser Thr Leu Ser Asn Arg Arg Phe
                 365                 370                 375

 Val Leu Cys Gly Thr Asn Val Lys Ala Met Ser Ile Glu Glu Ser
                 380                 385                 390

 Ser Asn Gly Ser Leu Ser Val Glu Phe Arg His Leu Gln Pro Lys
                 395                 400                 405

 Glu Met Lys Ser Ser Ala Gly Gly Lys Gly Asn Glu Gly Cys His
                 410                 415                 420

 Met Val Thr Glu Glu Leu His Ser Ile Thr Phe Glu Thr Gln Ile
                 425                 430                 435

 Cys Leu Tyr Gly Leu Thr Ile Asp Leu Glu Thr Ser Ser Leu Pro
                 440                 445                 450

 Val Val Met Ile Ser Asn Val Ser Gln Leu Pro Asn Ala Trp Ala
                 455                 460                 465

 Ser Ile Ile Trp Tyr Asn Val Ser Thr Asn Asp Ser Gln Asn Leu
                 470                 475                 480

 Val Phe Phe Asn Asn Pro Pro Pro Ala Thr Leu Ser Gln Leu Leu
                 485                 490                 495

 Glu Val Met Ser Trp Gln Phe Ser Ser Tyr Val Gly Arg Gly Leu
                 500                 505                 510

 Asn Ser Asp Gln Leu His Met Leu Ala Glu Lys Leu Thr Val Gln
                 515                 520                 525

 Ser Ser Tyr Ser Asp Gly His Leu Thr Trp Ala Lys Phe Cys Lys
                 530                 535                 540

 Glu His Leu Pro Gly Lys Ser Phe Thr Phe Trp Thr Trp Leu Glu
                 545                 550                 555

 Ala Ile Leu Asp Leu Ile Lys Lys His Ile Leu Pro Leu Trp Ile
                 560                 565                 570

 Asp Gly Tyr Val Met Gly Phe Val Ser Lys Glu Lys Glu Arg Leu
                 575                 580                 585

 Leu Leu Lys Asp Lys Met Pro Gly Thr Phe Leu Leu Arg Phe Ser
                 590                 595                 600

 Glu Ser His Leu Gly Gly Ile Thr Phe Thr Trp Val Asp His Ser
                 605                 610                 615

 Glu Ser Gly Glu Val Arg Phe His Ser Val Glu Pro Tyr Asn Lys
                 620                 625                 630

 Gly Arg Leu Ser Ala Leu Pro Phe Ala Asp Ile Leu Arg Asp Tyr
                 635                 640                 645

 Lys Val Ile Met Ala Glu Asn Ile Pro Glu Asn Pro Leu Lys Tyr
                 650                 655                 660

 Leu Tyr Pro Asp Ile Pro Lys Asp Lys Ala Phe Gly Lys His Tyr
                 665                 670                 675

 Ser Ser Gln Pro Cys Glu Val Ser Arg Pro Thr Glu Arg Gly Asp
                 680                 685                 690

 Lys Gly Tyr Val Pro Ser Val Phe Ile Pro Ile Ser Thr Ile Arg
                 695                 700                 705

 Ser Asp Ser Thr Glu Pro His Ser Pro Ser Asp Leu Leu Pro Met
                 710                 715                 720

 Ser Pro Ser Val Tyr Ala Val Leu Arg Glu Asn Leu Ser Pro Thr
                 725                 730                 735

 Thr Ile Glu Thr Ala Met Lys Ser Pro Tyr Ser Ala Glu
                 740                 745

<210> 1481
<211> 2824
<212> DNA
<213> Homo sapien

<400> 1481
 gctgccacct ctctagaggc acctggcggg gagcctctca acataagaca 50

 gtgaccagtc tggtgactca cagccggcac agccatgaac tacccgctaa 100

 cgctggaaat ggacctcgag aacctggagg acctgttctg ggaactggac 150

 agattggaca actataacga cacctccctg gtggaaaatc atctctgccc 200

 tgccacagag gggcccctca tggcctcctt caaggccgtg ttcgtgcccg 250

 tggcctacag cctcatcttc ctcctgggcg tgatcggcaa cgtcctggtg 300

 ctggtgatcc tggagcggca ccggcagaca cgcagttcca cggagacctt 350

 cctgttccac ctggccgtgg ccgacctcct gctggtcttc atcttgccct 400

 ttgccgtggc cgagggctct gtgggctggg tcctggggac cttcctctgc 450

 aaaactgtga ttgccctgca caaagtcaac ttctactgca gcagcctgct 500

 cctggcctgc atcgccgtgg accgctacct ggccattgtc cacgccgtcc 550

 atgcctaccg ccaccgccgc ctcctctcca tccacatcac ctgtgggacc 600

 atctggctgg tgggcttcct ccttgccttg ccagagattc tcttcgccaa 650

 agtcagccaa ggccatcaca acaactccct gccacgttgc accttctccc 700

 aagagaacca agcagaaacg catgcctggt tcacctcccg attcctctac 750

 catgtggcgg gattcctgct gcccatgctg gtgatgggct ggtgctacgt 800

 gggggtagtg cacaggttgc gccaggccca gcggcgccct cagcggcaga 850

 aggcagtcag ggtggccatc ctggtgacaa gcatcttctt cctctgctgg 900

 tcaccctacc acatcgtcat cttcctggac accctggcga ggctgaaggc 950

 cgtggacaat acctgcaagc tgaatggctc tctccccgtg gccatcacca 1000

 tgtgtgagtt cctgggcctg gcccactgct gcctcaaccc catgctctac 1050

 actttcgccg gcgtgaagtt ccgcagtgac ctgtcgcggc tcctgacgaa 1100

 gctgggctgt accggccctg cctccctgtg ccagctcttc cctagctggc 1150

 gcaggagcag tctctctgag tcagagaatg ccacctctct caccacgttc 1200

 taggtcccag tgtccccttt tattgctgct tttccttggg gcaggcagtg 1250

 atgctggatg ctccttccaa caggagctgg gatcctaagg gctcaccgtg 1300

 gctaagagtg tcctaggagt atcctcattt ggggtagcta gaggaaccaa 1350

 cccccatttc tagaacatcc ctgccagctc ttctgccggc cctggggcta 1400

 ggctggagcc cagggagcgg aaagcagctc aaaggcacag tgaaggctgt 1450

 ccttacccat ctgcaccccc ctgggctgag agaacctcac gcacctccca 1500

 tcctaatcat ccaatgctca agaaacaact tctacttctg cccttgccaa 1550

 cggagagcgc ctgcccctcc cagaacacac tccatcagct taggggctgc 1600

 tgacctccac agcttcccct ctctcctcct gcccacctgt caaacaaagc 1650

 cagaagctga gcaccagggg atgagtggag gttaaggctg aggaaaggcc 1700

 agctggcagc agagtgtggc cttcggacaa ctcagtccct aaaaacacag 1750

 acattctgcc aggcccccaa gcctgcagtc atcttgacca agcaggaagc 1800

 tcagactggt tgagttcagg tagctgcccc tggctctgac cgaaacagcg 1850

 ctgggtccac cccatgtcac cggatcctgg gtggtctgca ggcagggctg 1900

 actctaggtg cccttggagg ccagccagtg acctgaggaa gcgtgaaggc 1950

 cgagaagcaa gaaagaaacc cgacagaggg aagaaaagag ctttcttccc 2000

 gaaccccaag gagggagatg gatcaatcaa acccggcggt cccctccgcc 2050

 aggcgagatg gggtggggtg gagaactcct agggtggctg ggtccagggg 2100

 atgggaggtt gtgggcattg atggggaagg aggctggctt gtcccctcct 2150

 cactcccttc ccataagcta tagacccgag gaaactcaga gtcggaacgg 2200

 agaaaggtgg actggaaggg gcccgtggga gtcatctcaa ccatcccctc 2250

 cgtggcatca ccttaggcag ggaagtgtaa gaaacacact gaggcaggga 2300

 agtccccagg ccccaggaag ccgtgccctg cccccgtgag gatgtcactc 2350

 agatggaacc gcaggaagct gctccgtgct tgtttgctca cctggggtgt 2400

 gggaggcccg tccggcagtt ctgggtgctc cctaccacct ccccagcctt 2450

 tgatcaggtg gggagtcagg gacccctgcc cttgtcccac tcaagccaag 2500

 cagccaagct ccttgggagg ccccactggg gaaataacag ctgtggctca 2550

 cgtgagagtg tcttcacggc aggacaacga ggaagcccta agacgtccct 2600

 tttttctctg agtatctcct cgcaagctgg gtaatcgatg ggggagtctg 2650

 aagcagatgc aaagaggcaa gaggctggat tttgaatttt ctttttaata 2700

 aaaaggcacc tataaaacag gtcaatacag tacaggcagc acagagaccc 2750

 ccggaacaag cctaaaaatt gtttcaaaat aaaaaccaag aagatgtctt 2800

 caaaaaaaaa aaaaaaaaaa aaaa 2824

<210> 1482
<211> 372
<212> PRT
<213> Homo sapien

<400> 1482
 Met Asn Tyr Pro Leu Thr Leu Glu Met Asp Leu Glu Asn Leu Glu
   1               5                  10                  15

 Asp Leu Phe Trp Glu Leu Asp Arg Leu Asp Asn Tyr Asn Asp Thr
                  20                  25                  30

 Ser Leu Val Glu Asn His Leu Cys Pro Ala Thr Glu Gly Pro Leu
                  35                  40                  45

 Met Ala Ser Phe Lys Ala Val Phe Val Pro Val Ala Tyr Ser Leu
                  50                  55                  60

 Ile Phe Leu Leu Gly Val Ile Gly Asn Val Leu Val Leu Val Ile
                  65                  70                  75

 Leu Glu Arg His Arg Gln Thr Arg Ser Ser Thr Glu Thr Phe Leu
                  80                  85                  90

 Phe His Leu Ala Val Ala Asp Leu Leu Leu Val Phe Ile Leu Pro
                  95                 100                 105

 Phe Ala Val Ala Glu Gly Ser Val Gly Trp Val Leu Gly Thr Phe
                 110                 115                 120

 Leu Cys Lys Thr Val Ile Ala Leu His Lys Val Asn Phe Tyr Cys
                 125                 130                 135

 Ser Ser Leu Leu Leu Ala Cys Ile Ala Val Asp Arg Tyr Leu Ala
                 140                 145                 150

 Ile Val His Ala Val His Ala Tyr Arg His Arg Arg Leu Leu Ser
                 155                 160                 165

 Ile His Ile Thr Cys Gly Thr Ile Trp Leu Val Gly Phe Leu Leu
                 170                 175                 180

 Ala Leu Pro Glu Ile Leu Phe Ala Lys Val Ser Gln Gly His His
                 185                 190                 195

 Asn Asn Ser Leu Pro Arg Cys Thr Phe Ser Gln Glu Asn Gln Ala
                 200                 205                 210

 Glu Thr His Ala Trp Phe Thr Ser Arg Phe Leu Tyr His Val Ala
                 215                 220                 225

 Gly Phe Leu Leu Pro Met Leu Val Met Gly Trp Cys Tyr Val Gly
                 230                 235                 240

 Val Val His Arg Leu Arg Gln Ala Gln Arg Arg Pro Gln Arg Gln
                 245                 250                 255

 Lys Ala Val Arg Val Ala Ile Leu Val Thr Ser Ile Phe Phe Leu
                 260                 265                 270

 Cys Trp Ser Pro Tyr His Ile Val Ile Phe Leu Asp Thr Leu Ala
                 275                 280                 285

 Arg Leu Lys Ala Val Asp Asn Thr Cys Lys Leu Asn Gly Ser Leu
                 290                 295                 300

 Pro Val Ala Ile Thr Met Cys Glu Phe Leu Gly Leu Ala His Cys
                 305                 310                 315

 Cys Leu Asn Pro Met Leu Tyr Thr Phe Ala Gly Val Lys Phe Arg
                 320                 325                 330

 Ser Asp Leu Ser Arg Leu Leu Thr Lys Leu Gly Cys Thr Gly Pro
                 335                 340                 345

 Ala Ser Leu Cys Gln Leu Phe Pro Ser Trp Arg Arg Ser Ser Leu
                 350                 355                 360

 Ser Glu Ser Glu Asn Ala Thr Ser Leu Thr Thr Phe
                 365                 370

<210> 1483
<211> 2674
<212> DNA
<213> Homo sapien

<400> 1483
 cacacacggg cgcacgcaca cggcagccgg gccagggacg accctgtcag 50

 ctgcagcccc agaggtccgg ggcgcgcagc cgggtcccct cgagggcgca 100

 gccggccgcc ccgccccgcc cctcgaagca gccgggccgg gcgcgcagtg 150

 ggctacaaac tttcgcagcg cgagtccgcc aaggcagcgc gccgactcgg 200

 gctcggctcg gctctgcgct gctccggacg gctgtgaccg ctggccgggg 250

 gctcgggccg ccggtaccca cggaccgcgc gcccgggtgc ctgctccgct 300

 aagcccctcg ccccgcgcgg acctcggtat ccagcgccct gctgcccggg 350

 ctctccccgc gcgccctact gccgcgaggt cagtccgcag cctccggtgc 400

 gccagcgctc gccttcctcc tcctggactt cggccctttg ccgccctcac 450

 cacgccatgg ctcatgtccc cgctcggacc agcccgggac ccgggcccca 500

 gctgctgctg ctgctgctgc cgttgtttct gctgttgctc cgggatgtgg 550

 ccggcagcca cagggccccc gcctggtccg cactgcccgc ggccgccgac 600

 ggcctgcagg gggacaggga tctccagcgg caccctgggg acgcggccgc 650

 cacgttgggc cccagcgccc aggacatggt cgctgtccac atgcacaggc 700

 tctatgagaa gtacagccgg cagggcgcgc ggccgggagg gggcaacacg 750

 gtccgcagct tcagggccag gctggaagtg gtcgaccaga aggccgtgta 800

 tttcttcaac ctgacttcca tgcaagactc ggaaatgatc cttacggcca 850

 ctttccactt ctactcagag ccgcctcggt ggcctcgagc gctcgaggtg 900

 ctatgcaagc cgcgggccaa gaacgcttca ggccgcccgc tgcccctggg 950

 cccgcccaca cgccagcacc tgctcttccg cagcctctcg cagaacacgg 1000

 ccacacaggg gctactccgc ggggccatgg ccctggcgcc cccaccgcgc 1050

 ggcctgtggc aggccaagga catctccccc atcgtcaagg cggcccgccg 1100

 ggatggcgag ctgctcctct ccgcccagct ggattctgag gagagggacc 1150

 cgggggtgcc ccggcccagc ccctatgcgc cctacatcct agtctatgcc 1200

 aacgatctgg ccatctcgga gcccaacagc gtggcagtga cgctgcagag 1250

 atacgacccc ttccctgccg gagaccccga gccccgcgca gcccccaaca 1300

 actcagcgga cccccgcgtg cgccgagccg cgcaggccac tgggcccctc 1350

 caggacaacg agctgccggg gctggatgag aggccgccgc gcgcccacgc 1400

 acagcacttc cacaagcacc agctgtggcc cagccccttc cgggcgctga 1450

 aaccccggcc agggcgcaaa gaccgcagga agaagggcca ggaggtgttc 1500

 atggccgcct cgcaggtgct ggactttgac gagaagacga tgcagaaagc 1550

 ccggaggaag cagtgggatg agccgagggt gtgctcccgg aggtacctga 1600

 aggtggactt cgcagacatc ggctggaatg aatggataat ctcaccgaaa 1650

 tcttttgatg cctactactg cgcgggagca tgtgagttcc ccatgcctaa 1700

 gatcgttcgt ccatccaacc atgccaccat ccagagcatt gtcagggctg 1750

 tgggcatcat ccctggcatc ccagagccct gctgtgttcc cgataagatg 1800

 aactcccttg gggtcctctt cctggatgag aatcggaatg tggttctgaa 1850

 ggtgtacccc aacatgtccg tggacacctg tgcctgccgg tgagaccact 1900

 ccagggtgga aagaagccac gcccagcaga gctgccttct cggagccttc 1950

 tgcaaccagg acttgtggtg cagctgcaga cacagagcac agctcatggg 2000

 caacatcact ggggcccaga gagagctgtc cgccagtgca tcattagggg 2050

 gtctttcatt gctagtgact agccccttaa atgccagcct gagtacctga 2100

 aggaatctgg gaattagccc tggcctgaaa gtggcccatc attcataccc 2150

 actgttctga aggcttgaaa acaaaacata tccacaacat tggcttgatg 2200

 tgatcatcat ctcataactg agcaagaaga ctatgcaaat cttagggcgc 2250

 tcgctccctg cacacggaaa gaactctgtt taaatgctca gttcagaaca 2300

 ctttgggcca catagtgatt ttggaaaaca ggataatcgt ggtgtaaatg 2350

 agtgtttcct ttcaaagtcc actgcagagc ttttatccat atggtatgca 2400

 catgtagcca atattggttt ctttttctta atatatatat tttattttaa 2450

 aacaacaaaa agggagggcg ttgacaccat tccccacaga gatagtcatg 2500

 ctgagtgtgg gttgtttaaa catgcatatt gaaataacac atatagtaac 2550

 gtgggaatac taaaaaataa ccaagatttt atatttttgt aaattatact 2600

 ttctatactg tagattgtgt atgttatgtg tttttatgga aagctaataa 2650

 attaaaggta cagtggtatc ttga 2674

<210> 1484
<211> 478
<212> PRT
<213> Homo sapien

<400> 1484
 Met Ala His Val Pro Ala Arg Thr Ser Pro Gly Pro Gly Pro Gln
   1               5                  10                  15

 Leu Leu Leu Leu Leu Leu Pro Leu Phe Leu Leu Leu Leu Arg Asp
                  20                  25                  30

 Val Ala Gly Ser His Arg Ala Pro Ala Trp Ser Ala Leu Pro Ala
                  35                  40                  45

 Ala Ala Asp Gly Leu Gln Gly Asp Arg Asp Leu Gln Arg His Pro
                  50                  55                  60

 Gly Asp Ala Ala Ala Thr Leu Gly Pro Ser Ala Gln Asp Met Val
                  65                  70                  75

 Ala Val His Met His Arg Leu Tyr Glu Lys Tyr Ser Arg Gln Gly
                  80                  85                  90

 Ala Arg Pro Gly Gly Gly Asn Thr Val Arg Ser Phe Arg Ala Arg
                  95                 100                 105

 Leu Glu Val Val Asp Gln Lys Ala Val Tyr Phe Phe Asn Leu Thr
                 110                 115                 120

 Ser Met Gln Asp Ser Glu Met Ile Leu Thr Ala Thr Phe His Phe
                 125                 130                 135

 Tyr Ser Glu Pro Pro Arg Trp Pro Arg Ala Leu Glu Val Leu Cys
                 140                 145                 150

 Lys Pro Arg Ala Lys Asn Ala Ser Gly Arg Pro Leu Pro Leu Gly
                 155                 160                 165

 Pro Pro Thr Arg Gln His Leu Leu Phe Arg Ser Leu Ser Gln Asn
                 170                 175                 180

 Thr Ala Thr Gln Gly Leu Leu Arg Gly Ala Met Ala Leu Ala Pro
                 185                 190                 195

 Pro Pro Arg Gly Leu Trp Gln Ala Lys Asp Ile Ser Pro Ile Val
                 200                 205                 210

 Lys Ala Ala Arg Arg Asp Gly Glu Leu Leu Leu Ser Ala Gln Leu
                 215                 220                 225

 Asp Ser Glu Glu Arg Asp Pro Gly Val Pro Arg Pro Ser Pro Tyr
                 230                 235                 240

 Ala Pro Tyr Ile Leu Val Tyr Ala Asn Asp Leu Ala Ile Ser Glu
                 245                 250                 255

 Pro Asn Ser Val Ala Val Thr Leu Gln Arg Tyr Asp Pro Phe Pro
                 260                 265                 270

 Ala Gly Asp Pro Glu Pro Arg Ala Ala Pro Asn Asn Ser Ala Asp
                 275                 280                 285

 Pro Arg Val Arg Arg Ala Ala Gln Ala Thr Gly Pro Leu Gln Asp
                 290                 295                 300

 Asn Glu Leu Pro Gly Leu Asp Glu Arg Pro Pro Arg Ala His Ala
                 305                 310                 315

 Gln His Phe His Lys His Gln Leu Trp Pro Ser Pro Phe Arg Ala
                 320                 325                 330

 Leu Lys Pro Arg Pro Gly Arg Lys Asp Arg Arg Lys Lys Gly Gln
                 335                 340                 345

 Glu Val Phe Met Ala Ala Ser Gln Val Leu Asp Phe Asp Glu Lys
                 350                 355                 360

 Thr Met Gln Lys Ala Arg Arg Lys Gln Trp Asp Glu Pro Arg Val
                 365                 370                 375

 Cys Ser Arg Arg Tyr Leu Lys Val Asp Phe Ala Asp Ile Gly Trp
                 380                 385                 390

 Asn Glu Trp Ile Ile Ser Pro Lys Ser Phe Asp Ala Tyr Tyr Cys
                 395                 400                 405

 Ala Gly Ala Cys Glu Phe Pro Met Pro Lys Ile Val Arg Pro Ser
                 410                 415                 420

 Asn His Ala Thr Ile Gln Ser Ile Val Arg Ala Val Gly Ile Ile
                 425                 430                 435

 Pro Gly Ile Pro Glu Pro Cys Cys Val Pro Asp Lys Met Asn Ser
                 440                 445                 450

 Leu Gly Val Leu Phe Leu Asp Glu Asn Arg Asn Val Val Leu Lys
                 455                 460                 465

 Val Tyr Pro Asn Met Ser Val Asp Thr Cys Ala Cys Arg
                 470                 475

<210> 1485
<211> 1789
<212> DNA
<213> Homo sapien

<400> 1485
 ggttcaggaa cctgctggtt ctgatacata aatcagacag cctctgctgc 50

 atgacacgaa gcttgcttct gcctggcatc tgtgagcagc tgccaggctc 100

 cggccaggat cccttccttc tcctcattgg ctgatggatc ccaaggggct 150

 cctctccttg accttcgtgc tgtttctctc cctggctttt ggggcaagct 200

 acggaacagg tgggcgcatg atgaactgcc caaagattct ccggcagttg 250

 ggaagcaaag tgctgctgcc cctgacatat gaaaggataa ataagagcat 300

 gaacaaaagc atccacattg tcgtcacaat ggcaaaatca ctggagaaca 350

 gtgtcgagaa caaaatagtg tctcttgatc catccgaagc aggccctcca 400

 cgttatctag gagatcgcta caagttttat ctggagaatc tcaccctggg 450

 gatacgggaa agcaggaagg aggatgaggg atggtacctt atgaccctgg 500

 agaaaaatgt ttcagttcag cgcttttgcc tgcagttgag gctttatgag 550

 caggtctcca ctccagaaat taaagtttta aacaagaccc aggagaacgg 600

 gacctgcacc ttgatactgg gctgcacagt ggagaagggg gaccatgtgg 650

 cttacagctg gagtgaaaag gcgggcaccc acccactgaa cccagccaac 700

 agctcccacc tcctgtccct caccctcggc ccccagcatg ctgacaatat 750

 ctacatctgc accgtgagca accctatcag caacaattcc cagaccttca 800

 gcccgtggcc cggatgcagg acagacccct cagaaacaaa accatgggca 850

 gtgtatgctg ggctgttagg gggtgtcatc atgattctca tcatggtggt 900

 aatactacag ttgagaagaa gaggtaaaac gaaccattac cagacaacag 950

 tggaaaaaaa aagccttacg atctatgccc aagtccagaa accaggtcct 1000

 cttcagaaga aacttgactc cttcccagct caggaccctt gcaccaccat 1050

 atatgttgct gccacagagc ctgtcccaga gtctgtccag gaaacaaatt 1100

 ccatcacagt ctatgctagt gtgacacttc cagagagctg acaccagaga 1150

 ccaacaaagg gactttctga aggaaaatgg aaaaaccaaa atgaacactg 1200

 aacttggcca caggcccaag tttcctctgg cagacatgct gcacgtctgt 1250

 acccttctca gatcaactcc ctggtgatgt ttcttccaca tacatctgtg 1300

 aaatgaacaa ggaagtgagg cttcccaaga atttagcttg ctgtgcagtg 1350

 gctgcaggcg cagaacagag cgttacttga taacagcgtt ccatctttgt 1400

 gttgtagcag atgaaatgga cagtaatgtg agttcagact ttgggcatct 1450

 tgctcttggc tggaactgat aataaaaatc agactgaaag ccaggacatc 1500

 tgagtaccta tctcacacac tgaccaccag tcacaaagtc tggaaaagtt 1550

 tacattttgg ctatctttac tttgttctgg gagctgatca tgataacctg 1600

 cagacctgat caagcctctg tgcctcagtt tctctctcag gataaagagt 1650

 gaatagaggc cgaagggtga atttcttatt atacataaaa cactctgata 1700

 ttattgtata aaggaagcta agaatattat tttatttgca aaacccagaa 1750

 gctaaaaagt caataaacag aaagaatgat tttgagaaa 1789

<210> 1486
<211> 335
<212> PRT
<213> Homo sapien

<400> 1486
 Met Asp Pro Lys Gly Leu Leu Ser Leu Thr Phe Val Leu Phe Leu
   1               5                  10                  15

 Ser Leu Ala Phe Gly Ala Ser Tyr Gly Thr Gly Gly Arg Met Met
                  20                  25                  30

 Asn Cys Pro Lys Ile Leu Arg Gln Leu Gly Ser Lys Val Leu Leu
                  35                  40                  45

 Pro Leu Thr Tyr Glu Arg Ile Asn Lys Ser Met Asn Lys Ser Ile
                  50                  55                  60

 His Ile Val Val Thr Met Ala Lys Ser Leu Glu Asn Ser Val Glu
                  65                  70                  75

 Asn Lys Ile Val Ser Leu Asp Pro Ser Glu Ala Gly Pro Pro Arg
                  80                  85                  90

 Tyr Leu Gly Asp Arg Tyr Lys Phe Tyr Leu Glu Asn Leu Thr Leu
                  95                 100                 105

 Gly Ile Arg Glu Ser Arg Lys Glu Asp Glu Gly Trp Tyr Leu Met
                 110                 115                 120

 Thr Leu Glu Lys Asn Val Ser Val Gln Arg Phe Cys Leu Gln Leu
                 125                 130                 135

 Arg Leu Tyr Glu Gln Val Ser Thr Pro Glu Ile Lys Val Leu Asn
                 140                 145                 150

 Lys Thr Gln Glu Asn Gly Thr Cys Thr Leu Ile Leu Gly Cys Thr
                 155                 160                 165

 Val Glu Lys Gly Asp His Val Ala Tyr Ser Trp Ser Glu Lys Ala
                 170                 175                 180

 Gly Thr His Pro Leu Asn Pro Ala Asn Ser Ser His Leu Leu Ser
                 185                 190                 195

 Leu Thr Leu Gly Pro Gln His Ala Asp Asn Ile Tyr Ile Cys Thr
                 200                 205                 210

 Val Ser Asn Pro Ile Ser Asn Asn Ser Gln Thr Phe Ser Pro Trp
                 215                 220                 225

 Pro Gly Cys Arg Thr Asp Pro Ser Glu Thr Lys Pro Trp Ala Val
                 230                 235                 240

 Tyr Ala Gly Leu Leu Gly Gly Val Ile Met Ile Leu Ile Met Val
                 245                 250                 255

 Val Ile Leu Gln Leu Arg Arg Arg Gly Lys Thr Asn His Tyr Gln
                 260                 265                 270

 Thr Thr Val Glu Lys Lys Ser Leu Thr Ile Tyr Ala Gln Val Gln
                 275                 280                 285

 Lys Pro Gly Pro Leu Gln Lys Lys Leu Asp Ser Phe Pro Ala Gln
                 290                 295                 300

 Asp Pro Cys Thr Thr Ile Tyr Val Ala Ala Thr Glu Pro Val Pro
                 305                 310                 315

 Glu Ser Val Gln Glu Thr Asn Ser Ile Thr Val Tyr Ala Ser Val
                 320                 325                 330

 Thr Leu Pro Glu Ser
                 335

<210> 1487
<211> 5871
<212> DNA
<213> Homo sapien

<400> 1487
 gcaccacaga ccagtctgtc ctggtgttgg atgttaaaag tggagccaca 50

 aagaagccat cttatgtggg acaggcttgg gtgtgagacc agagctgtgg 100

 gtagcagcat gttgggtcag gatgaggggc agaggaaaca ctttccacct 150

 cttggatatg gattttatcc tgccctgatt caggagatcc ccatctatta 200

 agtaagggga aagatgattt tgttgtcttt tgtttcagat tctaatgtag 250

 gaactggtga gaagaaggtg actgaagcct ggatttctga ggatgaaaac 300

 tcacatagga cgacgtcaga cagactcacg gtgatggagc tcccctctcc 350

 cgagtctgag gaagtccacg agcccagatt aggggagctc ttgggaaatc 400

 cagaaggtca gagcctgggg agttccccct ctcaggacag gggctgcaag 450

 caggtgacag tgacccattg gaagatccag acaggagaga cagctcaagt 500

 gtgcaccaag tcaggaagaa accatattct gaactcagac cttcttctgc 550

 ttcagagaga gctcatagag ggggaagcca atccttgcga tatctgtggc 600

 aaaaccttca cgtttaattc ggacctagtt aggcatcgga tttcgcatgc 650

 tggggagaaa ccttacacgt gcgatcagtg tgggaaaggc tttggccaga 700

 gctcacacct tatggagcat cagagaattc acactggaga gagactctac 750

 gtctgtaatg tgtgtgggaa agacttcatt cactattcag gtctcattga 800

 gcatcagcgc gttcattcag gagaaaagcc cttcaaatgt gcgcagtgtg 850

 ggaaggcgtt ttgtcacagt tcagacctga ttaggcacca gagagttcac 900

 accagagaga gaccttttga atgcaaagag tgtgggaaag gcttcagtca 950

 gagctcctta cttattcgcc atcagaggat tcacacggga gaaaggccct 1000

 atgagtgcaa tgaatgtggg aaatccttca taaggagctc gagcctcatt 1050

 cgccattatc agatccacac agaagtgaaa cagtatgaat gcaaagaatg 1100

 tgggaaggca ttccgtcatc gctcagacct tattgaacac cagagaattc 1150

 acaccggaga gagacccttt gaatgcaatg agtgtgggaa agcctttatt 1200

 cggagttcaa agctcattca gcatcagagg atccatactg gggagaggcc 1250

 ttacgtatgc aatgagtgtg ggaagcgctt cagccagacg tcaaacttca 1300

 cccagcatca gagaattcac actggagaga aactctatga atgtaacgag 1350

 tgtgggaaag ctttctttct gagttcatac cttattcgac accagaaaat 1400

 ccacactgga gagagagtgt atgaatgtaa ggaatgtggg aaagcgtttc 1450

 tccagaaagc ccatctcact gagcaccaga agatccactc tggggacagg 1500

 cccttcgaat gtaaagactg tgggaaagcc ttcatccaga gctccaagct 1550

 gcttctgcac cagattattc acactggaga aaagccctat gtgtgcagtt 1600

 attgtgggaa aggctttatt cagaggtcaa acttccttca acaccagaaa 1650

 attcatactg aagagaagct ctatgaatgt agtcagtatg ggagagattt 1700

 taactcaact acaaacgtta aaaataatca aagggttcac caagagggac 1750

 tctccttgag taaggccccc atacatttgg gtgagaggtc tgtagataag 1800

 ggggaacaca caggtaactt ataaaataat tactttcccg cccagtgagt 1850

 gatgtttgga aatgcgtgga attaggattc atgtggtttc taagatttgg 1900

 acatgtcaga attttgtgag tcatggatgg ggctgctttt gcagtgggtg 1950

 ccacctgcca ctgtgcagcc ctactcggct cagcccttct cctcagctgt 2000

 gagcactgtc ctcaggagag tcacagggct tgacacctga ctctgagctg 2050

 gaacagtagg ggcagggaga agacaggtct caagaaaagg tttttaagaa 2100

 gtttcatccc cagttaagca gagtccatcc ttgacttaaa tcccttatta 2150

 cagcacaact gtgtatctaa tcttacgatt taggagaatg ttacctagga 2200

 cattttgatg tgttaagttg aagaaaggta actcgtgtat gaaccccgag 2250

 ccatttccct gttgtcctga ggaggaactc caggcctccc atcgtgtgcc 2300

 ctaaggcctc ctgcgtcctg gagccctgcc tcccactgcc tgacttcctg 2350

 ccacacggtt aatgctgcag caacaccgac tgcttcatct tccctgtgct 2400

 ccacgtggct tcctacctct ctcgcctttg ttcttgttga agggtctctt 2450

 ctcagctaat taactctgaa tcatggttca agacaagcct caggcatcat 2500

 gtcaatgggt gtttccctca agcttagttg gcagcactct ccacacttct 2550

 gtggctcagt gattactgct attactatat ttacttgcat atgtcagaat 2600

 gatgtgatag actatctctg tcactatgct gttgggttcc tgaggacagt 2650

 gatcatatct gattgatttc catgtgtcca ctgtctagca cagggcaata 2700

 aaaaatacac ccctaaatct atgtgtaatt ggcatctctc ttgctttgtc 2750

 ctttctatac tgccattcta aaaattttca gctgttggct gttttttttt 2800

 gttgtttgtt cattttgtat cagtataatc tacgattctg ttagaagtat 2850

 cttctcagcc ctgctactgt ctgctgctcc tacttagaag ttgcaggcaa 2900

 tatcctgtgc acatccacgc cctcctgtgt gccaccttac agctcatgca 2950

 gaactgtcta cttgatctgg agggcattga cacctggctc agctggaaca 3000

 gtggggacag gaggaggcag gtctcaagag aaggtcttta cttacttgtc 3050

 tgtatctttc tgtctcactc gaaaggcaca gtctcaatgc gctacgtaac 3100

 tcttctgttg tagcagttct gaggttgaac tgagctcttg tcattttcca 3150

 tgctctctgg ctcattgtgt catttcaaaa tgtattgata tctataagga 3200

 atagtcctca atgttgggaa aacagatgag caacccacta ccctgaagtc 3250

 atccaccgtg tagtggggaa gacggagatc acagtagggt gagttaagta 3300

 tgtgccctca ggtgtgaagg agcacaggtg agggggtgcc tgctgtggca 3350

 cagagctggg aaggccttac agaagaggtg acatttcagc tgggccagag 3400

 atcagtagag agcagctgaa gaagaaaata gggtccagga gaggaatctg 3450

 cagaaacatg gagccatgac agatggcttt ttggctagga ctgttcgaaa 3500

 gcaggcgagg taaatggaca gtggacagcc gcctcgccaa actgttagtc 3550

 tttacctctg aatttcatct ggacatgaac cccaaagtcc agttttgtaa 3600

 cgatataatt tttttctcat gaggccatat tttgagttct taaatactac 3650

 caaccctgaa cgtctcagga caaataattc aaaaaagaga tctacatttt 3700

 ctggaaaatc agcattacta gagatgtttc aaatgtagat tttaccagac 3750

 cattttaatc aactttattg agattcaatt ttcatatagt aaaacgccta 3800

 tttaagtgta caaggttttg aaaaatctat acacctgtgt aaccaccacc 3850

 acctgtgtaa ccaccaccgc cagaaccaaa aacgtttctg tcacccaaag 3900

 aagttccctt ttgccttttc ctagttaagc ccactccagc cccagataac 3950

 cactttctat cctcatagat tagtgttgct tggtttagag cctcatacaa 4000

 atggattcat ttactatgtg ttcttttgcg tctgatgtct cactttggca 4050

 tgtttttaga ctcatccaag ctgttttgtg tttcagtagt tctccttgct 4100

 gaatagtatt ccattgtgtg gataagccat catttgttta ttcatccacg 4150

 tgttaatggg tttccagtct cggctcttaa aactatgagc atttgtgtaa 4200

 aagtatgtat ttgcacatgt gtttttattt ctcttgggta agtacctagg 4250

 actttaattg ctgtgttgta agtgtcttag ttcattcagg ctgccataac 4300

 aaaataccat caactgggag gcttataaac aacagaaatt tatgttttac 4350

 agttctggag gctgggaagt ccaagatgag ggtgtcaaca tttggtgtct 4400

 agtgagggcc tgcttccttt taagtagatg tctttttact gtgactgcac 4450

 gtggtggaaa gggactagca agcttacccc attcatgagg gctctcccct 4500

 tgtgattctg tcccctcccc aagaccccac ctcatatcat cttatgggtt 4550

 aggaatttga catgaattgt gcaaggatgt aaacattcag tccattgcaa 4600

 tgcgtgtttc taacttccta agaaattgtc acacagccct ctgtagtggt 4650

 tgaatcattt tacactatta ctacattatg ggaagattcc agttgctcca 4700

 tatctttgct aacacttggc attgtcagtc tcttaaaatt taatccactc 4750

 tagcctcctt atgattttaa tttgtatttg cccactgaat aatgtatgtc 4800

 tatgatttca tctgcttatt gcttttccgt gtcgtctttt gtgatgtgtc 4850

 tgttcgtgcc ttttgcctgt ttttaagttg ggatgcttat tgttgactca 4900

 agttctttcc atattctgca tgaaaaacat acatgtaata tatagaattc 4950

 tttgtctcca tttgtgacaa atattgtgaa tattttcatg tttggtttgc 5000

 ctgttcattt tcttaatggt gtcttttgaa tattttttat taagccacca 5050

 ctcctggcca actgtagttg aactcaggta ttggaagggc ttccgttttg 5100

 ttcttttccc attttttttt tttgacttct agatcctttg cattttcgta 5150

 taaaatttga agtcaacttc tatcaacttc aggccaggcc cgtggctcat 5200

 gcctgtataa tcccagcact ttgggaggcc gaggcgggcg gatcgcttga 5250

 ggtcaggagt tcaagaccag cctggccggg gtggtgaaac cccatctcta 5300

 ctaaaaatgc ggaagagtta gccaggcgtg gtggcaggcg cctgtagaat 5350

 cccagctgct cgggaggctg aggcaggaga attgcttgag cctgggaggt 5400

 ggaggtttca gtgagctggg atcgtggcat tgcactctag cctgggcaac 5450

 caagagtgaa actgtctcaa aaaacaactt ttatcaatgt ctgcaaaaag 5500

 aaagtcttct gggatttata gatcaattta gggagaaatg acattttaac 5550

 aattctgagt tttccaattg ttgaacatgg tgtactgccc catttattta 5600

 gatctgttaa tttctctcag tttgcagctc tcacattttg ttaaattcat 5650

 gtatttaata tttctgcatg ctattgcaag tggtaaggtt ttcaaaaagc 5700

 tgttttctag ttattgctag tatatagaaa tgcattagac ttgtacattg 5750

 atcttgtatc aagcaactta gatcagttaa cttattctag tagctttttt 5800

 ctagattctt tagcattttc tatgtagata atcatgtcat ctgtgaataa 5850

 agtattttac ttttccaatt t 5871

<210> 1488
<211> 536
<212> PRT
<213> Homo sapien

<400> 1488
 Met Ile Leu Leu Ser Phe Val Ser Asp Ser Asn Val Gly Thr Gly
   1               5                  10                  15

 Glu Lys Lys Val Thr Glu Ala Trp Ile Ser Glu Asp Glu Asn Ser
                  20                  25                  30

 His Arg Thr Thr Ser Asp Arg Leu Thr Val Met Glu Leu Pro Ser
                  35                  40                  45

 Pro Glu Ser Glu Glu Val His Glu Pro Arg Leu Gly Glu Leu Leu
                  50                  55                  60

 Gly Asn Pro Glu Gly Gln Ser Leu Gly Ser Ser Pro Ser Gln Asp
                  65                  70                  75

 Arg Gly Cys Lys Gln Val Thr Val Thr His Trp Lys Ile Gln Thr
                  80                  85                  90

 Gly Glu Thr Ala Gln Val Cys Thr Lys Ser Gly Arg Asn His Ile
                  95                 100                 105

 Leu Asn Ser Asp Leu Leu Leu Leu Gln Arg Glu Leu Ile Glu Gly
                 110                 115                 120

 Glu Ala Asn Pro Cys Asp Ile Cys Gly Lys Thr Phe Thr Phe Asn
                 125                 130                 135

 Ser Asp Leu Val Arg His Arg Ile Ser His Ala Gly Glu Lys Pro
                 140                 145                 150

 Tyr Thr Cys Asp Gln Cys Gly Lys Gly Phe Gly Gln Ser Ser His
                 155                 160                 165

 Leu Met Glu His Gln Arg Ile His Thr Gly Glu Arg Leu Tyr Val
                 170                 175                 180

 Cys Asn Val Cys Gly Lys Asp Phe Ile His Tyr Ser Gly Leu Ile
                 185                 190                 195

 Glu His Gln Arg Val His Ser Gly Glu Lys Pro Phe Lys Cys Ala
                 200                 205                 210

 Gln Cys Gly Lys Ala Phe Cys His Ser Ser Asp Leu Ile Arg His
                 215                 220                 225

 Gln Arg Val His Thr Arg Glu Arg Pro Phe Glu Cys Lys Glu Cys
                 230                 235                 240

 Gly Lys Gly Phe Ser Gln Ser Ser Leu Leu Ile Arg His Gln Arg
                 245                 250                 255

 Ile His Thr Gly Glu Arg Pro Tyr Glu Cys Asn Glu Cys Gly Lys
                 260                 265                 270

 Ser Phe Ile Arg Ser Ser Ser Leu Ile Arg His Tyr Gln Ile His
                 275                 280                 285

 Thr Glu Val Lys Gln Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe
                 290                 295                 300

 Arg His Arg Ser Asp Leu Ile Glu His Gln Arg Ile His Thr Gly
                 305                 310                 315

 Glu Arg Pro Phe Glu Cys Asn Glu Cys Gly Lys Ala Phe Ile Arg
                 320                 325                 330

 Ser Ser Lys Leu Ile Gln His Gln Arg Ile His Thr Gly Glu Arg
                 335                 340                 345

 Pro Tyr Val Cys Asn Glu Cys Gly Lys Arg Phe Ser Gln Thr Ser
                 350                 355                 360

 Asn Phe Thr Gln His Gln Arg Ile His Thr Gly Glu Lys Leu Tyr
                 365                 370                 375

 Glu Cys Asn Glu Cys Gly Lys Ala Phe Phe Leu Ser Ser Tyr Leu
                 380                 385                 390

 Ile Arg His Gln Lys Ile His Thr Gly Glu Arg Val Tyr Glu Cys
                 395                 400                 405

 Lys Glu Cys Gly Lys Ala Phe Leu Gln Lys Ala His Leu Thr Glu
                 410                 415                 420

 His Gln Lys Ile His Ser Gly Asp Arg Pro Phe Glu Cys Lys Asp
                 425                 430                 435

 Cys Gly Lys Ala Phe Ile Gln Ser Ser Lys Leu Leu Leu His Gln
                 440                 445                 450

 Ile Ile His Thr Gly Glu Lys Pro Tyr Val Cys Ser Tyr Cys Gly
                 455                 460                 465

 Lys Gly Phe Ile Gln Arg Ser Asn Phe Leu Gln His Gln Lys Ile
                 470                 475                 480

 His Thr Glu Glu Lys Leu Tyr Glu Cys Ser Gln Tyr Gly Arg Asp
                 485                 490                 495

 Phe Asn Ser Thr Thr Asn Val Lys Asn Asn Gln Arg Val His Gln
                 500                 505                 510

 Glu Gly Leu Ser Leu Ser Lys Ala Pro Ile His Leu Gly Glu Arg
                 515                 520                 525

 Ser Val Asp Lys Gly Glu His Thr Gly Asn Leu
                 530                 535

<210> 1489
<211> 4137
<212> DNA
<213> Homo sapien

<400> 1489
 ggcacgagcg gcggaggcag tgtctcccgg tcgcgcgtgg aggtcggtcg 50

 ctcagagctg ctgggcgcag tttctccgcc tgctgcttcg gcgcggctgt 100

 atcggcgagc gagcgagttc ccgcgagttc tcggtggcgc tcccccttcc 150

 tttcagtctc cacggactgg cccctcgtcc ttctacttga ccgctcccgt 200

 cttccgccgc cttctggcgc tttccgttgg gccgattccc gcccgcttcc 250

 tcctgcttcc catcgaagct ctagaaatga atgtttccat ctcttcagag 300

 atgaaccaga ttatgatgca tcattatcac agaagaaatt cgtgtctata 350

 gcttttaagg acttgattac atcattttca agcctgatag ttttggaatc 400

 accattagag cttaagacac acctgccttc atttcaacca cctgtcttca 450

 taccctgacg aagtgcacct tttaacactc ctttgtcctt ggattactta 500

 agagttccca gaaatacatt tgccaccaac agagtagcca aatttataag 550

 gaaaaatgat tcccaatgga tatttgatgt ttgaggatga aaattttatt 600

 gagtcttctg ttgccaaatt aaatgccctg aggaaaagtg gccagttctg 650

 tgatgttcga cttcaggtct gtggccatga aatgttagca cacagagcag 700

 tgctagcttg ctgcagtccc tatttatttg aaatctttaa tagtgatagt 750

 gatcctcatg gaatttctca cgttaaattt gatgatctca atccagaagc 800

 tgttgaagtc ttgttgaatt atgcctacac tgctcagttg aaagcagata 850

 aggaattggt aaaagatgtt tattctgcag caaaaaagct gaagatggat 900

 cgagtaaagc aggtttgtgg tgattattta ctgtctagaa tggatgttac 950

 cagctgcatc tcttaccgaa attttgcaag ttgtatggga gactcccgtt 1000

 tgttgaataa ggttgatgct tatattcagg agcatttgtt acaaatttct 1050

 gaagaggagg agtttcttaa gcttccaagg ctaaagttgg aggtaatgct 1100

 tgaagataat gtttgcttgc ccagcaatgg caaattatat acaaaggtaa 1150

 tcaactgggt gcagcgtagc atctgggaga atggagacag tctggaagag 1200

 ctgatggaag aggttcaaac cttgtactac tcagctgatc acaagctgct 1250

 tgatgggaac ctactagatg gacaggctga ggtgtttggc agtgatgatg 1300

 accacattca gtttgtgcag aaaaagccac cacgtgagaa tggccataag 1350

 cagataagta gcagttcaac tggatgtctc tcttctccaa atgctacagt 1400

 acaaagccct aagcatgagt ggaaaatcgt tgcttcagaa aagacttcaa 1450

 ataacactta cttgtgcctg gctgtgctgg atggtatatt ctgtgtcatt 1500

 tttcttcatg ggagaaacag cccacagagc tcaccaacaa gtactccaaa 1550

 actaagtaag agtttaagct ttgagatgca acaagatgag ctaatcgaaa 1600

 agcccatgtc tcctatgcag tacgcacgat ctggtctggg aacagcagag 1650

 atgaatggca aactcatagc tgcaggtggc tataacagag aggaatgtct 1700

 tcgaacagtc gaatgctata atccacatac agatcactgg tcctttcttg 1750

 ctcccatgag aacaccaaga gcccgatttc aaatggctgt actcatgggc 1800

 cagctctatg tggtaggtgg atcaaatggc cactcagatg acctgagttg 1850

 tggagagatg tatgattcaa acatagatga ctggattcct gttccagaat 1900

 tgagaactaa ccgttgtaat gcaggagtgt gtgctctgaa tggaaagtta 1950

 tacatcgttg gtggctctga tccatatggt caaaaaggac tgaaaaattg 2000

 tgatgtattt gatcctgtaa caaagttgtg gacaagctgt gcccctctta 2050

 acattcggag acaccagtct gcagtctgtg agcttggtgg ttatttgtac 2100

 ataatcggag gtgcagaatc ttggaattgt ctgaacacag tagaacgata 2150

 caatcctgaa aataatacct ggactttaat tgcacccatg aatgtggcta 2200

 ggcgaggagc tggagtggct gttcttaatg gaaaactgtt tgtatgtggt 2250

 ggctttgatg gttctcatgc catcagttgt gtggaaatgt atgatccaac 2300

 tagaaatgaa tggaagatga tgggaaatat gacttcacca aggagcaatg 2350

 ctgggattgc aactgtaggg aacaccattt atgcagtggg aggattcgat 2400

 ggcaatgaat ttctgaatac ggtggaagtc tataaccttg agtcaaatga 2450

 atggagcccc tatacaaaga ttttccagtt ttaacaaatt taagaccctc 2500

 tcaaactaac aggcttagtg atgtaattat ggttagcaga ggtacacttg 2550

 tgaataaaga gggtgggtgg gtatagatgt tgctaacagc aacacaaagc 2600

 ttttgcatat tgcatactat taaacatgct gtacatactt tttgggttta 2650

 tttggaaagg aatgcaaaga tgaaggtctg ttttgtgtac ttttaagact 2700

 ttggttattt tactttttgg aaaagaataa accaagaatt gattgggcac 2750

 atcatttcaa gaagtcccct ctcctccaca tttgttttgc caatttgcac 2800

 attaaatgac tcttccctca aatgtgtact atggggtaaa aggggtaggg 2850

 tttaaagatg tagacagttg ggttttttaa gggccctttt tcaataactg 2900

 gaacactcta taacaaagga tacttattta aatagatgac attgactatt 2950

 tttgttttta ttaaaaggaa gcttacatgc ctaccaatat ttaatctttt 3000

 atgattgcct ttttataact ttttatattc tcagcagagt gctttaccaa 3050

 ttgaagtaaa atgtggcagg ctggagttat tgaagcagag tggcagtctt 3100

 cagtttgcag agtaggggtc tgtcttttaa actctgagtg caaacttcag 3150

 agttcttgcc ttggctgcag tttttttcct tcaagaatgc agtactaaca 3200

 tttatttgag tggagttact gaacagtaac atagctgtga tttttggtat 3250

 ttgaaacact ggttttaaat attttgactt gttgagggta tgttttatat 3300

 agcaagacat tatatagcag taaaaaatgg tgttttatct tctatataat 3350

 tcctgttttt attattaaca aaacagtcct aaatagcagc cctcaattgt 3400

 gaaaaaattt actttaaact acattaggtt gtgaatgcag gttttatcag 3450

 aactatgttt ttgttcagtt tatctgttca tatggataaa tattggttgg 3500

 gatgacttgg tgtctaatgt gtagtgctac acacctaact tatggggcca 3550

 aaatagcatg tcctaatgct tgctgctgat ttaaacacat taaaggtact 3600

 ttgcaggaaa tccttgcacc atgggattaa tatccaattg ctgcttgtac 3650

 actcattcat tactaaaagt tttgagaaat ttttttttcc agtaatgagc 3700

 ttaagaaatt tgtggaaaat aactcacctg gcatcttaca tctgaaataa 3750

 ggaatgatat aaggtttttt tttctcacag aagatgaagc acacaggaac 3800

 ctaatgggcc aactgggatg aggtgactat tctgagatga ctattcagtg 3850

 gctaacttgg gttaggaaga aaataattag gtattttctc caaatgttca 3900

 ctggtactct gccactttat ttctctcatc tgttacacaa agaaccacca 3950

 ggaaagcaaa tcagtttggt tggtaactct gtaattccta actatcactg 4000

 gtttggttct ggactaaaac tacattgaca gattgaattt gcctaatatg 4050

 atgactgttt ttaatatgga tctgtatgtg ttctattcag cccaaggaaa 4100

 taaaatttta gttgaggatt caaaaaaaaa aaaaaaa 4137

<210> 1490
<211> 642
<212> PRT
<213> Homo sapien

<400> 1490
 Met Ile Pro Asn Gly Tyr Leu Met Phe Glu Asp Glu Asn Phe Ile
   1               5                  10                  15

 Glu Ser Ser Val Ala Lys Leu Asn Ala Leu Arg Lys Ser Gly Gln
                  20                  25                  30

 Phe Cys Asp Val Arg Leu Gln Val Cys Gly His Glu Met Leu Ala
                  35                  40                  45

 His Arg Ala Val Leu Ala Cys Cys Ser Pro Tyr Leu Phe Glu Ile
                  50                  55                  60

 Phe Asn Ser Asp Ser Asp Pro His Gly Ile Ser His Val Lys Phe
                  65                  70                  75

 Asp Asp Leu Asn Pro Glu Ala Val Glu Val Leu Leu Asn Tyr Ala
                  80                  85                  90

 Tyr Thr Ala Gln Leu Lys Ala Asp Lys Glu Leu Val Lys Asp Val
                  95                 100                 105

 Tyr Ser Ala Ala Lys Lys Leu Lys Met Asp Arg Val Lys Gln Val
                 110                 115                 120

 Cys Gly Asp Tyr Leu Leu Ser Arg Met Asp Val Thr Ser Cys Ile
                 125                 130                 135

 Ser Tyr Arg Asn Phe Ala Ser Cys Met Gly Asp Ser Arg Leu Leu
                 140                 145                 150

 Asn Lys Val Asp Ala Tyr Ile Gln Glu His Leu Leu Gln Ile Ser
                 155                 160                 165

 Glu Glu Glu Glu Phe Leu Lys Leu Pro Arg Leu Lys Leu Glu Val
                 170                 175                 180

 Met Leu Glu Asp Asn Val Cys Leu Pro Ser Asn Gly Lys Leu Tyr
                 185                 190                 195

 Thr Lys Val Ile Asn Trp Val Gln Arg Ser Ile Trp Glu Asn Gly
                 200                 205                 210

 Asp Ser Leu Glu Glu Leu Met Glu Glu Val Gln Thr Leu Tyr Tyr
                 215                 220                 225

 Ser Ala Asp His Lys Leu Leu Asp Gly Asn Leu Leu Asp Gly Gln
                 230                 235                 240

 Ala Glu Val Phe Gly Ser Asp Asp Asp His Ile Gln Phe Val Gln
                 245                 250                 255

 Lys Lys Pro Pro Arg Glu Asn Gly His Lys Gln Ile Ser Ser Ser
                 260                 265                 270

 Ser Thr Gly Cys Leu Ser Ser Pro Asn Ala Thr Val Gln Ser Pro
                 275                 280                 285

 Lys His Glu Trp Lys Ile Val Ala Ser Glu Lys Thr Ser Asn Asn
                 290                 295                 300

 Thr Tyr Leu Cys Leu Ala Val Leu Asp Gly Ile Phe Cys Val Ile
                 305                 310                 315

 Phe Leu His Gly Arg Asn Ser Pro Gln Ser Ser Pro Thr Ser Thr
                 320                 325                 330

 Pro Lys Leu Ser Lys Ser Leu Ser Phe Glu Met Gln Gln Asp Glu
                 335                 340                 345

 Leu Ile Glu Lys Pro Met Ser Pro Met Gln Tyr Ala Arg Ser Gly
                 350                 355                 360

 Leu Gly Thr Ala Glu Met Asn Gly Lys Leu Ile Ala Ala Gly Gly
                 365                 370                 375

 Tyr Asn Arg Glu Glu Cys Leu Arg Thr Val Glu Cys Tyr Asn Pro
                 380                 385                 390

 His Thr Asp His Trp Ser Phe Leu Ala Pro Met Arg Thr Pro Arg
                 395                 400                 405

 Ala Arg Phe Gln Met Ala Val Leu Met Gly Gln Leu Tyr Val Val
                 410                 415                 420

 Gly Gly Ser Asn Gly His Ser Asp Asp Leu Ser Cys Gly Glu Met
                 425                 430                 435

 Tyr Asp Ser Asn Ile Asp Asp Trp Ile Pro Val Pro Glu Leu Arg
                 440                 445                 450

 Thr Asn Arg Cys Asn Ala Gly Val Cys Ala Leu Asn Gly Lys Leu
                 455                 460                 465

 Tyr Ile Val Gly Gly Ser Asp Pro Tyr Gly Gln Lys Gly Leu Lys
                 470                 475                 480

 Asn Cys Asp Val Phe Asp Pro Val Thr Lys Leu Trp Thr Ser Cys
                 485                 490                 495

 Ala Pro Leu Asn Ile Arg Arg His Gln Ser Ala Val Cys Glu Leu
                 500                 505                 510

 Gly Gly Tyr Leu Tyr Ile Ile Gly Gly Ala Glu Ser Trp Asn Cys
                 515                 520                 525

 Leu Asn Thr Val Glu Arg Tyr Asn Pro Glu Asn Asn Thr Trp Thr
                 530                 535                 540

 Leu Ile Ala Pro Met Asn Val Ala Arg Arg Gly Ala Gly Val Ala
                 545                 550                 555

 Val Leu Asn Gly Lys Leu Phe Val Cys Gly Gly Phe Asp Gly Ser
                 560                 565                 570

 His Ala Ile Ser Cys Val Glu Met Tyr Asp Pro Thr Arg Asn Glu
                 575                 580                 585

 Trp Lys Met Met Gly Asn Met Thr Ser Pro Arg Ser Asn Ala Gly
                 590                 595                 600

 Ile Ala Thr Val Gly Asn Thr Ile Tyr Ala Val Gly Gly Phe Asp
                 605                 610                 615

 Gly Asn Glu Phe Leu Asn Thr Val Glu Val Tyr Asn Leu Glu Ser
                 620                 625                 630

 Asn Glu Trp Ser Pro Tyr Thr Lys Ile Phe Gln Phe
                 635                 640

<210> 1491
<211> 2644
<212> DNA
<213> Homo sapien

<400> 1491
 gaccgcggca gctcagcctc ccgccgattg tatgttccag gcctcaatga 50

 ggagtccaaa catggagcca ttcaagcagc agaaggtgga ggacttttat 100

 gacatcggag aggagctggg gagtggccag tttgccatcg tgaagaagtg 150

 ccgggagaag agcacggggc ttgagtatgc agccaagttc atcaagaagc 200

 ggcagagccg ggcgagccgg cgcggtgtga gccgggagga gatcgagcgg 250

 gaggtgagca tcctgcggca ggtgctgcac cacaatgtca tcacgctgca 300

 cgacgtctat gagaaccgca ccgacgtggt gctcatcctt gagctagtgt 350

 ctggaggaga gctcttcgat ttcctggccc agaaggagtc actgagtgag 400

 gaggaggcca ccagcttcat taagcagatc ctggatgggg tgaactacct 450

 tcacacaaag aaaattgctc actttgatct caagccagaa aacattatgt 500

 tgttagacaa gaatattccc attccacaca tcaagctgat tgactttggt 550

 ctggctcacg aaatagaaga tggagttgaa tttaagaata tttttgggac 600

 gccggaattt gttgctccag aaattgtgaa ctacgagccc ctgggtctgg 650

 aggctgacat gtggagcata ggcgtcatca cctacatcct cttaagtgga 700

 gcatcccctt tcctgggaga cacgaagcag gaaacactgg caaatatcac 750

 agcagtgagt tacgactttg atgaggaatt cttcagccag acgagcgagc 800

 tggccaagga ctttattcgg aagcttctgg ttaaagagac ccggaaacgg 850

 ctcacaatcc aagaggctct cagacacccc tggatcacgc cggtggacaa 900

 ccagcaagcc atggtgcgca gggagtctgt ggtcaatctg gagaacttca 950

 ggaagcagta tgtccgcagg cggtggaagc tttccttcag catcgtgtcc 1000

 ctgtgcaacc acctcacccg ctcgctgatg aagaaggtgc acctgaggcc 1050

 ggatgaggac ctgaggaact gtgagagtga cactgaggag gacatcgcca 1100

 ggaggaaagc cctccaccca cggaggagga gcagcacctc ctaactggcc 1150

 tgacctgcag tggccgccag ggaggtctgg gcccagcggg gctcccttct 1200

 gtgcagactt ttggacccag ctcagcacca gcacccgggc gtcctgagca 1250

 ctttgcaaga gagatgggcc caaggaattc agaagagctt gcaggcaagc 1300

 caggagaccc tgggagctgt ggctgtcttc tgtggaggag gctccagcat 1350

 tcccaaagct cttaattctc cataaaatgg gctttcctct gtctgccatc 1400

 ctcagagtct ggggtgggag tgtggactta ggaaaacaat ataaaggaca 1450

 tcctcatcat cacggggtga aggtcagact aaggcagcct tcttcacagg 1500

 ctgagggggt tcagaaccag cctggccaaa aattacacca gagagacaga 1550

 gtcctcccca ttgggaacag ggtgattgag gaaagtgaac cttgggtgtg 1600

 agggaccaat cctgtgacct cccagaacca tggaagccag gacgtcaggc 1650

 tgaccaacac ctcagacctt ctgaagcagc ccattgctgg cccgccatgt 1700

 tgtaattttg ctcattttta ttaaacttct ggtttacctg atgcttggct 1750

 tcttttaggg ctacccccat ctcatttcct ttagcccgtg tgcctgtaac 1800

 tctgaggggg ggcacccagt ggggtgctga gtgggcagaa tctcagaagg 1850

 tcctcctgaa ccgtccgcgc aggcctgcag tgggcctgcc tcctccttgc 1900

 ttccctaaca ggaaggtgtc cagttcaaga gaacccaccc agagactggg 1950

 agtggtggct cacgcctata atccctgcgc tttggcagtc cgaggcaggg 2000

 gaattgcttg aactcaggag ttggagacca gcctgggcaa catggcaaaa 2050

 ctcagtctgt acaaaaaata caaaaaatta gccaggtgta ggggtaggca 2100

 cctggcatcc cagctactcc aggggctgag gtgacagcat tgcttaagcc 2150

 cagaaggtcg aggctgcagt gagctgagat cacgccactg cactccagtc 2200

 tgggtgacag agagagacca tatccaaaaa aaaaaaaagt tgccagagac 2250

 gagtatgccc atgctccctc tacctcactg ccaccactcc tgcttttagg 2300

 agctgagtgt gtctccctaa aatttctatg ttgaagtctt aacccttggt 2350

 accacagaat atcactgtat ttggagatgg ggtctttaga aaggcactta 2400

 aattaaaatg agctcactga tatgggcccc gatgcaatat aattggtgtc 2450

 cttataagaa ggggaggtta ggacacgcag gaaagaccac atgaaggccc 2500

 aggagtggga gggggaatag ccatcgacaa actaaggggg cctcagagga 2550

 aaccaaccct gctgacacct caatcttaga ctctggcctc aaaaattgta 2600

 agaaaataaa cttctgtctt ttaagccaaa aaaaaaaaaa aaaa 2644

<210> 1492
<211> 370
<212> PRT
<213> Homo sapien

<400> 1492
 Met Phe Gln Ala Ser Met Arg Ser Pro Asn Met Glu Pro Phe Lys
   1               5                  10                  15

 Gln Gln Lys Val Glu Asp Phe Tyr Asp Ile Gly Glu Glu Leu Gly
                  20                  25                  30

 Ser Gly Gln Phe Ala Ile Val Lys Lys Cys Arg Glu Lys Ser Thr
                  35                  40                  45

 Gly Leu Glu Tyr Ala Ala Lys Phe Ile Lys Lys Arg Gln Ser Arg
                  50                  55                  60

 Ala Ser Arg Arg Gly Val Ser Arg Glu Glu Ile Glu Arg Glu Val
                  65                  70                  75

 Ser Ile Leu Arg Gln Val Leu His His Asn Val Ile Thr Leu His
                  80                  85                  90

 Asp Val Tyr Glu Asn Arg Thr Asp Val Val Leu Ile Leu Glu Leu
                  95                 100                 105

 Val Ser Gly Gly Glu Leu Phe Asp Phe Leu Ala Gln Lys Glu Ser
                 110                 115                 120

 Leu Ser Glu Glu Glu Ala Thr Ser Phe Ile Lys Gln Ile Leu Asp
                 125                 130                 135

 Gly Val Asn Tyr Leu His Thr Lys Lys Ile Ala His Phe Asp Leu
                 140                 145                 150

 Lys Pro Glu Asn Ile Met Leu Leu Asp Lys Asn Ile Pro Ile Pro
                 155                 160                 165

 His Ile Lys Leu Ile Asp Phe Gly Leu Ala His Glu Ile Glu Asp
                 170                 175                 180

 Gly Val Glu Phe Lys Asn Ile Phe Gly Thr Pro Glu Phe Val Ala
                 185                 190                 195

 Pro Glu Ile Val Asn Tyr Glu Pro Leu Gly Leu Glu Ala Asp Met
                 200                 205                 210

 Trp Ser Ile Gly Val Ile Thr Tyr Ile Leu Leu Ser Gly Ala Ser
                 215                 220                 225

 Pro Phe Leu Gly Asp Thr Lys Gln Glu Thr Leu Ala Asn Ile Thr
                 230                 235                 240

 Ala Val Ser Tyr Asp Phe Asp Glu Glu Phe Phe Ser Gln Thr Ser
                 245                 250                 255

 Glu Leu Ala Lys Asp Phe Ile Arg Lys Leu Leu Val Lys Glu Thr
                 260                 265                 270

 Arg Lys Arg Leu Thr Ile Gln Glu Ala Leu Arg His Pro Trp Ile
                 275                 280                 285

 Thr Pro Val Asp Asn Gln Gln Ala Met Val Arg Arg Glu Ser Val
                 290                 295                 300

 Val Asn Leu Glu Asn Phe Arg Lys Gln Tyr Val Arg Arg Arg Trp
                 305                 310                 315

 Lys Leu Ser Phe Ser Ile Val Ser Leu Cys Asn His Leu Thr Arg
                 320                 325                 330

 Ser Leu Met Lys Lys Val His Leu Arg Pro Asp Glu Asp Leu Arg
                 335                 340                 345

 Asn Cys Glu Ser Asp Thr Glu Glu Asp Ile Ala Arg Arg Lys Ala
                 350                 355                 360

 Leu His Pro Arg Arg Arg Ser Ser Thr Ser
                 365                 370

<210> 1493
<211> 2139
<212> DNA
<213> Homo sapien

<400> 1493
 gtgagacagg ggtagtgcga ggccgggcac agccttcctg tgtggtttta 50

 ccgcccagag agcgtcatgg acctggggaa accaatgaaa agcgtgctgg 100

 tggtggctct ccttgtcatt ttccaggtat gcctgtgtca agatgaggtc 150

 acggacgatt acatcggaga caacaccaca gtggactaca ctttgttcga 200

 gtctttgtgc tccaagaagg acgtgcggaa ctttaaagcc tggttcctcc 250

 ctatcatgta ctccatcatt tgtttcgtgg gcctactggg caatgggctg 300

 gtcgtgttga cctatatcta tttcaagagg ctcaagacca tgaccgatac 350

 ctacctgctc aacctggcgg tggcagacat cctcttcctc ctgacccttc 400

 ccttctgggc ctacagcgcg gccaagtcct gggtcttcgg tgtccacttt 450

 tgcaagctca tctttgccat ctacaagatg agcttcttca gtggcatgct 500

 cctacttctt tgcatcagca ttgaccgcta cgtggccatc gtccaggctg 550

 tctcagctca ccgccaccgt gcccgcgtcc ttctcatcag caagctgtcc 600

 tgtgtgggca tctggatact agccacagtg ctctccatcc cagagctcct 650

 gtacagtgac ctccagagga gcagcagtga gcaagcgatg cgatgctctc 700

 tcatcacaga gcatgtggag gcctttatca ccatccaggt ggcccagatg 750

 gtgatcggct ttctggtccc cctgctggcc atgagcttct gttaccttgt 800

 catcatccgc accctgctcc aggcacgcaa ctttgagcgc aacaaggcca 850

 tcaaggtgat catcgctgtg gtcgtggtct tcatagtctt ccagctgccc 900

 tacaatgggg tggtcctggc ccagacggtg gccaacttca acatcaccag 950

 tagcacctgt gagctcagta agcaactcaa catcgcctac gacgtcacct 1000

 acagcctggc ctgcgtccgc tgctgcgtca accctttctt gtacgccttc 1050

 atcggcgtca agttccgcaa cgatctcttc aagctcttca aggacctggg 1100

 ctgcctcagc caggagcagc tccggcagtg gtcttcctgt cggcacatcc 1150

 ggcgctcctc catgagtgtg gaggccgaga ccaccaccac cttctcccca 1200

 taggcgactc ttctgcctgg actagaggga cctctcccag ggtccctggg 1250

 gtggggatag ggagcagatg caatgactca ggacatcccc ccgccaaaag 1300

 ctgctcaggg aaaagcagct ctcccctcag agtgcaagcc ctgctccaga 1350

 agttagcttc accccaatcc cagctacctc aaccaatgcc gaaaaagaca 1400

 gggctgataa gctaacacca gacagacaac actgggaaac agaggctatt 1450

 gtcccctaaa ccaaaaactg aaagtgaaag tccagaaact gttcccacct 1500

 gctggagtga aggggccaag gagggtgagt gcaaggggcg tgggagtggc 1550

 ctgaagagtc ctctgaatga accttctggc ctcccacaga ctcaaatgct 1600

 cagaccagct cttccgaaaa ccaggcctta tctccaagac cagagatagt 1650

 ggggagactt cttggcttgg tgaggaaaag cggacatcag ctggtcaaac 1700

 aaactctctg aacccctccc tccatcgttt tcttcactgt cctccaagcc 1750

 agcgggaatg gcagctgcca cgccgcccta aaagcacact catcccctca 1800

 cttgccgcgt cgccctccca ggctctcaac aggggagagt gtggtgtttc 1850

 ctgcaggcca ggccagctgc ctccgcgtga tcaaagccac actctgggct 1900

 ccagagtggg gatgacatgc actcagctct tggctccact gggatgggag 1950

 gagaggacaa gggaaatgtc aggggcgggg agggtgacag tggccgccca 2000

 aggccacgag cttgttcttt gttctttgtc acagggactg aaaacctctc 2050

 ctcatgttct gctttcgatt cgttaagaga gcaacatttt acccacacac 2100

 agataaagtt ttcccttgag gaaacaacag ctttaaaag 2139

<210> 1494
<211> 378
<212> PRT
<213> Homo sapien

<400> 1494
 Met Asp Leu Gly Lys Pro Met Lys Ser Val Leu Val Val Ala Leu
   1               5                  10                  15

 Leu Val Ile Phe Gln Val Cys Leu Cys Gln Asp Glu Val Thr Asp
                  20                  25                  30

 Asp Tyr Ile Gly Asp Asn Thr Thr Val Asp Tyr Thr Leu Phe Glu
                  35                  40                  45

 Ser Leu Cys Ser Lys Lys Asp Val Arg Asn Phe Lys Ala Trp Phe
                  50                  55                  60

 Leu Pro Ile Met Tyr Ser Ile Ile Cys Phe Val Gly Leu Leu Gly
                  65                  70                  75

 Asn Gly Leu Val Val Leu Thr Tyr Ile Tyr Phe Lys Arg Leu Lys
                  80                  85                  90

 Thr Met Thr Asp Thr Tyr Leu Leu Asn Leu Ala Val Ala Asp Ile
                  95                 100                 105

 Leu Phe Leu Leu Thr Leu Pro Phe Trp Ala Tyr Ser Ala Ala Lys
                 110                 115                 120

 Ser Trp Val Phe Gly Val His Phe Cys Lys Leu Ile Phe Ala Ile
                 125                 130                 135

 Tyr Lys Met Ser Phe Phe Ser Gly Met Leu Leu Leu Leu Cys Ile
                 140                 145                 150

 Ser Ile Asp Arg Tyr Val Ala Ile Val Gln Ala Val Ser Ala His
                 155                 160                 165

 Arg His Arg Ala Arg Val Leu Leu Ile Ser Lys Leu Ser Cys Val
                 170                 175                 180

 Gly Ile Trp Ile Leu Ala Thr Val Leu Ser Ile Pro Glu Leu Leu
                 185                 190                 195

 Tyr Ser Asp Leu Gln Arg Ser Ser Ser Glu Gln Ala Met Arg Cys
                 200                 205                 210

 Ser Leu Ile Thr Glu His Val Glu Ala Phe Ile Thr Ile Gln Val
                 215                 220                 225

 Ala Gln Met Val Ile Gly Phe Leu Val Pro Leu Leu Ala Met Ser
                 230                 235                 240

 Phe Cys Tyr Leu Val Ile Ile Arg Thr Leu Leu Gln Ala Arg Asn
                 245                 250                 255

 Phe Glu Arg Asn Lys Ala Ile Lys Val Ile Ile Ala Val Val Val
                 260                 265                 270

 Val Phe Ile Val Phe Gln Leu Pro Tyr Asn Gly Val Val Leu Ala
                 275                 280                 285

 Gln Thr Val Ala Asn Phe Asn Ile Thr Ser Ser Thr Cys Glu Leu
                 290                 295                 300

 Ser Lys Gln Leu Asn Ile Ala Tyr Asp Val Thr Tyr Ser Leu Ala
                 305                 310                 315

 Cys Val Arg Cys Cys Val Asn Pro Phe Leu Tyr Ala Phe Ile Gly
                 320                 325                 330

 Val Lys Phe Arg Asn Asp Leu Phe Lys Leu Phe Lys Asp Leu Gly
                 335                 340                 345

 Cys Leu Ser Gln Glu Gln Leu Arg Gln Trp Ser Ser Cys Arg His
                 350                 355                 360

 Ile Arg Arg Ser Ser Met Ser Val Glu Ala Glu Thr Thr Thr Thr
                 365                 370                 375

 Phe Ser Pro


<210> 1495
<211> 1314
<212> DNA
<213> Homo sapien

<400> 1495
 cggctgtgtt gcgcagtctt catgggttcc cgacgaggag gtctctgtgg 50

 ctgcggcggc ggctgctaac tgcgccacct gctgcagcct gtccccgccg 100

 ctctgaagcg gccgcgtcga agccgaaatg ccgccacccc ggaccggccg 150

 aggccttctc tggctgggtc tggttctgag ctccgtctgc gtcgccctcg 200

 gatccgaaac gcaggccaac tcgaccacag atgctctgaa cgttcttctc 250

 atcatcgtgg atgacctgcg cccctccctg ggctgttatg gggataagct 300

 ggtgaggtcc ccaaatattg accaactggc atcccacagc ctcctcttcc 350

 agaatgcctt tgcgcagcaa gcagtgtgcg ccccgagccg cgtttctttc 400

 ctcactggca ggagacctga caccacccgc ctgtacgact tcaactccta 450

 ctggagggtg cacgctggaa acttctccac catcccccag tacttcaagg 500

 agaatggcta tgtgaccatg tcggtgggaa aagtctttca ccctgggata 550

 tcttctaacc ataccgatga ttctccgtat agctggtctt ttccacctta 600

 tcatccttcc tctgagaagt atgaaaacac taagacatgt cgagggccag 650

 atggagaact ccatgccaac ctgctttgcc ctgtggatgt gctggatgtt 700

 cccgagggca ccttgcctga caaacagagc actgagcaag ccatacagtt 750

 gttggaaaag atgaaaacgt cagccagtcc tttcttcctg gccgttgggt 800

 atcataagcc acacatcccc ttcagatacc ccaaggaatt tcagaagttg 850

 tatcccttgg agaacatcac cctggccccc gatcccgagg tccctgatgg 900

 cctaccccct gtggcctaca acccctggat ggacatcagg caacgggaag 950

 acgtccaagc cttaaacatc agtgtgccgt atggtccaat tcctgtggac 1000

 tttcagcgga aaatccgcca gagctacttt gcctctgtgt catatttgga 1050

 tacacaggtc ggccgcctct tgagtgcttt ggacgatctt cagctggcca 1100

 acagcaccat cattgcattt acctcggatc atggtttcct catgaggaca 1150

 aatacctgat tttgaataaa gcagcattca gttgaaataa ccctttctgt 1200

 ggtaattcca agtgaatatt tttcttctag gtgatgagtt tctacttcct 1250

 ctggttttta caacaggaaa tgaaatggta tctaaaataa acaagctgtg 1300

 gtatgatgat aatt 1314

<210> 1496
<211> 343
<212> PRT
<213> Homo sapien

<400> 1496
 Met Pro Pro Pro Arg Thr Gly Arg Gly Leu Leu Trp Leu Gly Leu
   1               5                  10                  15

 Val Leu Ser Ser Val Cys Val Ala Leu Gly Ser Glu Thr Gln Ala
                  20                  25                  30

 Asn Ser Thr Thr Asp Ala Leu Asn Val Leu Leu Ile Ile Val Asp
                  35                  40                  45

 Asp Leu Arg Pro Ser Leu Gly Cys Tyr Gly Asp Lys Leu Val Arg
                  50                  55                  60

 Ser Pro Asn Ile Asp Gln Leu Ala Ser His Ser Leu Leu Phe Gln
                  65                  70                  75

 Asn Ala Phe Ala Gln Gln Ala Val Cys Ala Pro Ser Arg Val Ser
                  80                  85                  90

 Phe Leu Thr Gly Arg Arg Pro Asp Thr Thr Arg Leu Tyr Asp Phe
                  95                 100                 105

 Asn Ser Tyr Trp Arg Val His Ala Gly Asn Phe Ser Thr Ile Pro
                 110                 115                 120

 Gln Tyr Phe Lys Glu Asn Gly Tyr Val Thr Met Ser Val Gly Lys
                 125                 130                 135

 Val Phe His Pro Gly Ile Ser Ser Asn His Thr Asp Asp Ser Pro
                 140                 145                 150

 Tyr Ser Trp Ser Phe Pro Pro Tyr His Pro Ser Ser Glu Lys Tyr
                 155                 160                 165

 Glu Asn Thr Lys Thr Cys Arg Gly Pro Asp Gly Glu Leu His Ala
                 170                 175                 180

 Asn Leu Leu Cys Pro Val Asp Val Leu Asp Val Pro Glu Gly Thr
                 185                 190                 195

 Leu Pro Asp Lys Gln Ser Thr Glu Gln Ala Ile Gln Leu Leu Glu
                 200                 205                 210

 Lys Met Lys Thr Ser Ala Ser Pro Phe Phe Leu Ala Val Gly Tyr
                 215                 220                 225

 His Lys Pro His Ile Pro Phe Arg Tyr Pro Lys Glu Phe Gln Lys
                 230                 235                 240

 Leu Tyr Pro Leu Glu Asn Ile Thr Leu Ala Pro Asp Pro Glu Val
                 245                 250                 255

 Pro Asp Gly Leu Pro Pro Val Ala Tyr Asn Pro Trp Met Asp Ile
                 260                 265                 270

 Arg Gln Arg Glu Asp Val Gln Ala Leu Asn Ile Ser Val Pro Tyr
                 275                 280                 285

 Gly Pro Ile Pro Val Asp Phe Gln Arg Lys Ile Arg Gln Ser Tyr
                 290                 295                 300

 Phe Ala Ser Val Ser Tyr Leu Asp Thr Gln Val Gly Arg Leu Leu
                 305                 310                 315

 Ser Ala Leu Asp Asp Leu Gln Leu Ala Asn Ser Thr Ile Ile Ala
                 320                 325                 330

 Phe Thr Ser Asp His Gly Phe Leu Met Arg Thr Asn Thr
                 335                 340

<210> 1497
<211> 2901
<212> DNA
<213> Homo sapien

<400> 1497
 cagcctccct ctcccacctc tgtctgcccg ctgcctcttg tctagctgct 50

 gtcaggagct gactgcctcc agggctggaa tcctgtgctc cctctgtgcc 100

 cagagcccca cgatgtcggc caacgccaca ctgaagccac tctgccccat 150

 cctggagcag atgagccgtc tccagagcca cagcaacacc agcatccgct 200

 acatcgacca cgcggccgtg ctgctgcacg ggctggcctc gctgctgggc 250

 ctggtggaga atggagtcat cctcttcgtg gtgggctgcc gcatgcgcca 300

 gaccgtggtc accacctggg tgctgcacct ggcgctgtcc gacctgttgg 350

 cctctgcttc cctgcccttc ttcacctact tcttggccgt gggccactcg 400

 tgggagctgg gcaccacctt ctgcaaactg cactcctcca tcttctttct 450

 caacatgttc gccagcggct tcctgctcag cgccatcagc ctggaccgct 500

 gcctgcaggt ggtgcggccg gtgtgggcgc agaaccaccg caccgtggcc 550

 gcggcgcaca aagtctgcct ggtgctttgg gcactagcgg tgctcaacac 600

 ggtgccctat ttcgtgttcc gggacaccat ctcgcggctg gacgggcgca 650

 ttatgtgcta ctacaatgtg ctgctcctga acccggggcc tgaccgcgat 700

 gccacgtgca actcgcgcca ggcggccctg gccgtcagca agttcctgct 750

 ggccttcctg gtgccgctgg cgatcatcgc ctcgagccac gcggccgtga 800

 gcctgcggtt gcagcaccgc ggccgccggc ggccaggccg cttcgtgcgc 850

 ctggtggcag ccgtcgtggc cgccttcgcg ctctgctggg ggccctacca 900

 cgtgttcagc ctgctggagg cgcgggcgca cgcaaacccg gggctgcggc 950

 cgctcgtgtg gcgcgggctg cccttcgtca ccagcctggc cttcttcaac 1000

 agcgtggcca acccggtgct ctacgtgctc acctgccccg acatgctgcg 1050

 caagctgcgg cgctcgctgc gcacggtgct ggagagcgtg ctggtggacg 1100

 acagcgagct gggtggcgcg ggaagcagcc gccgccgccg cacctcctcc 1150

 accgcccgct cggcctcccc tttagctctc tgcagccgcc cggaggaacc 1200

 gcggggcccc gcgcgtctcc tcggctggct gctgggcagc tgcgcagcgt 1250

 ccccgcagac gggccccctg aaccgggcgc tgagcagcac ctcgagttag 1300

 aacccggccc acgtagggcg gcactcacac gcgaaagtat caccagggtg 1350

 ccgcggttca attcgatatc cggactcctg ccgcagtgat caaagtccga 1400

 ggggcgggac ccaggcacct gcattttaaa gcgccccggg agactctgaa 1450

 tctttttcag aaacagtgag ttaaagcagt gcttctcaaa ccttgatgtg 1500

 cctgtgaatc acctaggggt cttgttaagt gcagtctgat ccaggaggcc 1550

 ggggccgggt actgagagtc tgcacttaac aagctcccag gccgagaagc 1600

 cagtgcggca ggttcacagg cgaggcctgg agtaacacaa agtgaaactc 1650

 gtaatagact tcccactcta gggcagtgga gtcggaaggg cacacggggt 1700

 gcgtctcccc ggagttcagt tttaccagat gatgggggag gggggaagga 1750

 gttttatgtt aaaccatcca tgtatttttg gagaagagag aggaaaggtt 1800

 tgagaagcac tgttccagcc tgccctcttc atttagccaa tgcttactgc 1850

 gctagacgct tcatcccaca atcttaaggg gcagcttcta ttagccagtc 1900

 tttacagctg agcacattct ggctcaggga ggttaagtga cttgcccagt 1950

 ttcagggcta acgaccacag ggtctgcact ctaaccctag gcatcacatg 2000

 ctcaatgact ctctggtgag cgaggacatt ctctgaccta ctcgagggac 2050

 ttaagatgct accttgtgac ccagcactgc ccaaagtgct tccaaggcag 2100

 aagcagcagg ggatggcgtg gtcaagcact cgggaaacct ggggctaatc 2150

 aaatccaatg ggggaaatga ctaaaagtct tcggtcgtta gaagttgaat 2200

 gggcacagca actctaagac tacagcacac gtcatttctt agctaagcgg 2250

 accagcctcc ctgtcggcct ggtgttctgt gggatccctc tgggcactgg 2300

 taatcccaag atctgtgcag ccccgcctcc aggccacatg gggctgggca 2350

 gctaccattt cccttttgcg gatgggaggg gtaacttgca cctctgacct 2400

 atcacttcca ctgcaccccg tctcattcct ccacctgccg tggacttggg 2450

 gtcagagact gctgtgtttg agctctgcag cccagggacc gaaaagttgg 2500

 tgtcaatgaa ttttgcttgg tggatgaaat gtcagtggaa gaagcagatg 2550

 agaaactctt gagatcttgg tcctgtgttt tttctgccac caaaggccag 2600

 ggtcactgaa ggcctggccc acagcaggtg ctgagcaaag ggaacagtga 2650

 ggtgcccagc tagctgcaga gccaccctgt gttgacacct cgcccctgct 2700

 ccctcccatc ccttccccct ttactcatag cacttccccc attggacacg 2750

 tggtgcattt tgcttgttta ttatgttttc tctccatcag aatgaaagct 2800

 cctcgagggc agggactttg gtctattgtc tgtatttgcc ggtgcctagg 2850

 attgtgcctg tatgcaacag gcactcaata aatatttttg ctgtagactg 2900

 g 2901

<210> 1498
<211> 395
<212> PRT
<213> Homo sapien

<400> 1498
 Met Ser Ala Asn Ala Thr Leu Lys Pro Leu Cys Pro Ile Leu Glu
   1               5                  10                  15

 Gln Met Ser Arg Leu Gln Ser His Ser Asn Thr Ser Ile Arg Tyr
                  20                  25                  30

 Ile Asp His Ala Ala Val Leu Leu His Gly Leu Ala Ser Leu Leu
                  35                  40                  45

 Gly Leu Val Glu Asn Gly Val Ile Leu Phe Val Val Gly Cys Arg
                  50                  55                  60

 Met Arg Gln Thr Val Val Thr Thr Trp Val Leu His Leu Ala Leu
                  65                  70                  75

 Ser Asp Leu Leu Ala Ser Ala Ser Leu Pro Phe Phe Thr Tyr Phe
                  80                  85                  90

 Leu Ala Val Gly His Ser Trp Glu Leu Gly Thr Thr Phe Cys Lys
                  95                 100                 105

 Leu His Ser Ser Ile Phe Phe Leu Asn Met Phe Ala Ser Gly Phe
                 110                 115                 120

 Leu Leu Ser Ala Ile Ser Leu Asp Arg Cys Leu Gln Val Val Arg
                 125                 130                 135

 Pro Val Trp Ala Gln Asn His Arg Thr Val Ala Ala Ala His Lys
                 140                 145                 150

 Val Cys Leu Val Leu Trp Ala Leu Ala Val Leu Asn Thr Val Pro
                 155                 160                 165

 Tyr Phe Val Phe Arg Asp Thr Ile Ser Arg Leu Asp Gly Arg Ile
                 170                 175                 180

 Met Cys Tyr Tyr Asn Val Leu Leu Leu Asn Pro Gly Pro Asp Arg
                 185                 190                 195

 Asp Ala Thr Cys Asn Ser Arg Gln Ala Ala Leu Ala Val Ser Lys
                 200                 205                 210

 Phe Leu Leu Ala Phe Leu Val Pro Leu Ala Ile Ile Ala Ser Ser
                 215                 220                 225

 His Ala Ala Val Ser Leu Arg Leu Gln His Arg Gly Arg Arg Arg
                 230                 235                 240

 Pro Gly Arg Phe Val Arg Leu Val Ala Ala Val Val Ala Ala Phe
                 245                 250                 255

 Ala Leu Cys Trp Gly Pro Tyr His Val Phe Ser Leu Leu Glu Ala
                 260                 265                 270

 Arg Ala His Ala Asn Pro Gly Leu Arg Pro Leu Val Trp Arg Gly
                 275                 280                 285

 Leu Pro Phe Val Thr Ser Leu Ala Phe Phe Asn Ser Val Ala Asn
                 290                 295                 300

 Pro Val Leu Tyr Val Leu Thr Cys Pro Asp Met Leu Arg Lys Leu
                 305                 310                 315

 Arg Arg Ser Leu Arg Thr Val Leu Glu Ser Val Leu Val Asp Asp
                 320                 325                 330

 Ser Glu Leu Gly Gly Ala Gly Ser Ser Arg Arg Arg Arg Thr Ser
                 335                 340                 345

 Ser Thr Ala Arg Ser Ala Ser Pro Leu Ala Leu Cys Ser Arg Pro
                 350                 355                 360

 Glu Glu Pro Arg Gly Pro Ala Arg Leu Leu Gly Trp Leu Leu Gly
                 365                 370                 375

 Ser Cys Ala Ala Ser Pro Gln Thr Gly Pro Leu Asn Arg Ala Leu
                 380                 385                 390

 Ser Ser Thr Ser Ser
                 395

<210> 1499
<211> 2145
<212> DNA
<213> Homo sapien

<400> 1499
 atcttttttc atcttctagc tgtagctcgg gctgcttgtc ggcttggctc 50

 cccctccccc ctttgctctc tgcctcgtct ttccccagga cttcgctatt 100

 ttgctttttt aaaaaaaggc aagaaagaac taaactcccc cctccctctc 150

 ctccagtcgg gctgcacctc tgccttgcac tttgcacaga ggtagagagc 200

 gcgcgaggga gagagaggaa agaaaaaaaa taataaagag agccaagcag 250

 aagaggaggc gagaagcatg aagtgttaac tcccccgtgc caaggcccgc 300

 gccgcccgga cagacgcccg ccgcgccttc cagccccgag cggacgccgc 350

 gcgccgccct gcctgcagcc cgggccggcg acggcgagcc cttccttatg 400

 caaagcgcgc cagcagcgcg aaggcgggac gccgcgcacc gggccgggct 450

 cctccagctt cgccgccgca gccaccaccg ccgccaccgc agctcgcgga 500

 ggatcttccc gagcctgaag ccgccggctc ggcgcgcaag gaggcgagcg 550

 caaggagggg ccggggcgag cgagggagca cattggcgtg agcagggggg 600

 agggagggcg ggcgcggggg gcgcgggcag ggcggggggg tgtgtgtgtg 650

 agcgcgcttg gaggtttcgg gccagccacc gccgcgcaag ctagaagcgc 700

 cccagcccgg caagctggct cacccgctgg ccacccagca cagcccgctg 750

 gcccctctcc tgcagcccat ctggcggagc ggcggcggcg gcggcggcgg 800

 caggagaatg gcatcagaac tggcaatgag caactccgac ctgcccacca 850

 gtcccctggc catggaatat gttaatgact tcgatctgat gaagtttgaa 900

 gtgaaaaagg aaccggtgga gaccgaccgc atcatcagcc agtgcggccg 950

 tctcatcgcc gggggctcgc tgtcctccac ccccatgagc acgccgtgca 1000

 gctcggtgcc cccttccccc agcttctcgg cgcccagccc gggctcgggc 1050

 agcgagcaga aggcgcacct ggaagactac tactggatga ccggctaccc 1100

 gcagcagctg aaccccgagg cgctgggctt cagccccgag gacgcggtcg 1150

 aggcgctcat cagcaacagc caccagctcc agggcggctt cgatggctac 1200

 gcgcgcgggg cgcagcagct ggccgcggcg gccggggccg gtgccggcgc 1250

 ctccttgggc ggcagcggcg aggagatggg ccccgcggcc gccgtggtgt 1300

 ccgccgtgat cgccgcggcc gccgcgcaga gcggcgcggg cccgcactac 1350

 caccaccacc accaccacgc cgccggccac caccaccacc cgacggccgg 1400

 cgcgcccggc gccgcgggca gcgcggccgc ctcggccggt ggcgctgggg 1450

 gcgcgggcgg cggtggcccg gccagcgctg ggggcggcgg cggcggcggc 1500

 ggcggcggag gcggcggggg cgcggcgggg gcggggggcg ccctgcaccc 1550

 gcaccacgcc gccggcggcc tgcacttcga cgaccgcttc tccgacgagc 1600

 agctggtgac catgtctgtg cgcgagctga accggcagct gcgcggggtc 1650

 agcaaggagg aggtgatccg gctgaagcag aagaggcgga ccctgaaaaa 1700

 ccgcggctat gcccagtcct gccgcttcaa gagggtgcag cagagacacg 1750

 tcctggagtc ggagaagaac cagctgctgc agcaagtcga ccacctcaag 1800

 caggagatct ccaggctggt gcgcgagagg gacgcgtaca aggagaaata 1850

 cgagaagttg gtgagcagcg gcttccgaga aaacggctcg agcagcgaca 1900

 acccgtcctc tcccgagttt ttcataactg agcccactcg caagttggag 1950

 ccatcagtgg gatacgccac attttggaag ccccagcatc gtgtacttac 2000

 cagtgtgttc acaaaatgaa atttgtgtga gagctgtaca ttaaaaaaaa 2050

 catcattatt attattattt gcagtcatgg agaaccacct acccctgact 2100

 tctgtttagt ctccttttta aataatactg tgttagaaaa aaaaa 2145

<210> 1500
<211> 403
<212> PRT
<213> Homo sapien

<400> 1500
 Met Ala Ser Glu Leu Ala Met Ser Asn Ser Asp Leu Pro Thr Ser
   1               5                  10                  15

 Pro Leu Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Met Lys Phe
                  20                  25                  30

 Glu Val Lys Lys Glu Pro Val Glu Thr Asp Arg Ile Ile Ser Gln
                  35                  40                  45

 Cys Gly Arg Leu Ile Ala Gly Gly Ser Leu Ser Ser Thr Pro Met
                  50                  55                  60

 Ser Thr Pro Cys Ser Ser Val Pro Pro Ser Pro Ser Phe Ser Ala
                  65                  70                  75

 Pro Ser Pro Gly Ser Gly Ser Glu Gln Lys Ala His Leu Glu Asp
                  80                  85                  90

 Tyr Tyr Trp Met Thr Gly Tyr Pro Gln Gln Leu Asn Pro Glu Ala
                  95                 100                 105

 Leu Gly Phe Ser Pro Glu Asp Ala Val Glu Ala Leu Ile Ser Asn
                 110                 115                 120

 Ser His Gln Leu Gln Gly Gly Phe Asp Gly Tyr Ala Arg Gly Ala
                 125                 130                 135

 Gln Gln Leu Ala Ala Ala Ala Gly Ala Gly Ala Gly Ala Ser Leu
                 140                 145                 150

 Gly Gly Ser Gly Glu Glu Met Gly Pro Ala Ala Ala Val Val Ser
                 155                 160                 165

 Ala Val Ile Ala Ala Ala Ala Ala Gln Ser Gly Ala Gly Pro His
                 170                 175                 180

 Tyr His His His His His His Ala Ala Gly His His His His Pro
                 185                 190                 195

 Thr Ala Gly Ala Pro Gly Ala Ala Gly Ser Ala Ala Ala Ser Ala
                 200                 205                 210

 Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Pro Ala Ser Ala Gly
                 215                 220                 225

 Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala
                 230                 235                 240

 Gly Ala Gly Gly Ala Leu His Pro His His Ala Ala Gly Gly Leu
                 245                 250                 255

 His Phe Asp Asp Arg Phe Ser Asp Glu Gln Leu Val Thr Met Ser
                 260                 265                 270

 Val Arg Glu Leu Asn Arg Gln Leu Arg Gly Val Ser Lys Glu Glu
                 275                 280                 285

 Val Ile Arg Leu Lys Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly
                 290                 295                 300

 Tyr Ala Gln Ser Cys Arg Phe Lys Arg Val Gln Gln Arg His Val
                 305                 310                 315

 Leu Glu Ser Glu Lys Asn Gln Leu Leu Gln Gln Val Asp His Leu
                 320                 325                 330

 Lys Gln Glu Ile Ser Arg Leu Val Arg Glu Arg Asp Ala Tyr Lys
                 335                 340                 345

 Glu Lys Tyr Glu Lys Leu Val Ser Ser Gly Phe Arg Glu Asn Gly
                 350                 355                 360

 Ser Ser Ser Asp Asn Pro Ser Ser Pro Glu Phe Phe Ile Thr Glu
                 365                 370                 375

 Pro Thr Arg Lys Leu Glu Pro Ser Val Gly Tyr Ala Thr Phe Trp
                 380                 385                 390

 Lys Pro Gln His Arg Val Leu Thr Ser Val Phe Thr Lys
                 395                 400

<210> 1501
<211> 6586
<212> DNA
<213> Homo sapien

<400> 1501
 ctggggagcc ggcgctggag gtggtgagtg gcgtggggac tgtgtcgagg 50

 gggtccccaa ggtgccggac cctgcggagg ggcgaagttt cggcactggg 100

 gagggcgtgc ggacgctttc cctacaggcg accactgctc tgcgggcggg 150

 tggtcttagc tccagtcccc cattcagttc ctcagcattc caggtcggcg 200

 gcgaaggggt ccccgaacga agggcgcaag gcagcgtctc tgctgggacc 250

 gggaagccgg acttcagggc ctctcggccc gtgggcttct ccccgagtct 300

 ccccgagtcg gttggcatta agagtttagc agatactttc agaaatggat 350

 acataagaaa tggctggaaa tcaaatgaat gtccaaagaa gagcttaggg 400

 tcttagtaac attctttttt aaaataactg tctgccaaaa tgtcattaca 450

 cagtactcat aatagaaata acagcggtga tattcttgat attccttctt 500

 cccaaaatag ttcatcactg aatgccctca cccacagtag ccgacttaag 550

 ctgcatttga agtcggatat gtcagaatgt gaaaatgatg atccattatt 600

 gagatctgca ggtaaagtca gagacataaa tagaacttat gttatttctg 650

 ccagtagaaa aacagcagac atgcccctta cccctaatcc tgtaggtaga 700

 ttggcacttc agaggagaac tacaaggaac aaagaatcat ctttgcttgt 750

 tagtgagttg gaagacacaa ctgaaaaaac agcagaaaca cgtcttacat 800

 tacaacgtcg tgctaaaaca gattctgcag aaaagtggaa aacagctgaa 850

 atagattctg tcaaaatgac actgaatgtg ggaggtgaaa cagaaaataa 900

 tggtgtttct aaggaaagta gaacaaatgt aaggattgta aataatgcta 950

 aaaactcttt tgttgcctct tctgtacctt tagatgaaga tccacaggtc 1000

 attgaaatga tggctgataa gaaatacaaa gaaacatttt ctgcccccag 1050

 tagagcaaat gaaaatgttg cacttaagta ctcaagtaat agaccaccca 1100

 ttgcttccct gagtcagact gaagttgtta gatcaggaca cttgacaacg 1150

 aaacctactc agagcaagtt ggatatcaaa gtgttgggaa caggaaactt 1200

 gtatcataga agtattggga aggaaattgc aaaaacttca aataaatttg 1250

 ggagcttaga aaaaagaaca cctacaaaat gtacaacaga acacaaactg 1300

 acaacaaagt gcagcctgcc tcagcttaag agcccagctc catcaatact 1350

 gaagaataga atgtctaacc ttcaagttaa acaaagacca aaaagttcct 1400

 ttcttgcaaa taaacaggaa agatccgcag aaaatacaat tcttcccgaa 1450

 gaagaaactg tagttcagaa cacctctgca ggaaaagacc ccttaaaagt 1500

 agagaatagt caagtgacag tggcagtacg cgtaagacct ttcaccaaga 1550

 gagagaagat tgaaaaagca tcccaggtag tcttcatgag tgggaaagaa 1600

 ataactgtgg aacaccctga cacgaaacaa gtttataatt ttatttatga 1650

 tgtttcattc tggtcttttg atgaatgtca tcctcactac gctagccaga 1700

 caactgtcta tgagaagcta gcagcaccac tcctagaaag agccttcgaa 1750

 ggcttcaata cctgtctttt tgcttatggt cagactggct ctggaaaatc 1800

 atatacgatg atgggattta gtgaagaacc aggaataatt ccaagatttt 1850

 gtgaagatct tttttctcaa gtagccagaa aacaaaccca agaggtcagc 1900

 tatcacattg aaatgagctt ctttgaagta tataatgaaa aaattcacga 1950

 ccttctggtt tgtaaagatg aaaatgggca gagaaagcaa ccactgagag 2000

 tgagggaaca tcctgtttat ggaccatatg ttgaagcact gtcaatgaac 2050

 attgtcagtt cttacgctga tatccagagt tggctagaat tgggaaataa 2100

 acaaagagct actgctgcta ctggtatgaa tgataaaagt tcccgatctc 2150

 attcagtttt caccctggtg atgacccaga ccaagacaga atttgtggaa 2200

 ggggaagaac acgatcacag aataacaagt cgaattaacc taatagatct 2250

 ggcaggcagt gagcgctgct ctacggctca cactaatgga gatcgactaa 2300

 aggaaggtgt gagtattaat aagtccttgc taactttggg aaaagttata 2350

 tctgcacttt cggaacaagc aaaccaaagg agtgttttta ttccttatcg 2400

 tgaatctgtt cttacatggc tgttaaaaga aagtctgggt ggaaattcaa 2450

 aaactgcaat gattgctacg attagtcccg ctgccagcaa catagaagaa 2500

 acattaagca cacttagata tgctaaccaa gcccgtttaa tagtcaacat 2550

 tgctaaagta aatgaagata tgaacgctaa gttaattaga gaattgaagg 2600

 cagaaattgc aaagctaaaa gctgctcaga gaaacagtcg gaatattgac 2650

 cctgaacgat acaggctctg tcggcaagaa ataacatcct taagaatgaa 2700

 actgcatcaa caggagagag acatggcaga aatgcaaaga gtgtggaaag 2750

 aaaagtttga acaagctgaa aaaagaaaac ttcaagaaac aaaagagtta 2800

 cagaaagcag gaattatgtt tcaaatggac aatcatttac caaaccttgt 2850

 taatctgaat gaagatccac aactatctga gatgctgcta tatatgataa 2900

 aagaaggaac aactacagtt ggaaagtata aaccaaactc aagccatgat 2950

 attcagttat ctggggtgct gattgctgat gatcattgta ctatcaaaaa 3000

 ttttggtggg acagtgagta ttatcccagt tggggaagca aagacatatg 3050

 taaatggaaa acatattttg gaaatcacag tattacgtca tggtgatcga 3100

 gtgattcttg gtggagatca ttattttaga tttaatcatc cagtagaagt 3150

 ccagaaagga aaaaggccat ctggaagaga tactcctata agtgagggtc 3200

 caaaagactt tgaatttgca aaaaatgagt tgctcatggc acagagatca 3250

 caacttgaag cagaaataaa agaggctcag ttgaaggcaa aggaagaaat 3300

 gatgcaagga atccagattg caaaagaaat ggctcagcaa gagctttctt 3350

 ctcaaaaagc tgcatatgaa agcaaaataa aagcactgga agcagaactg 3400

 agagaagagt ctcaaaggaa aaaaatgcag gaaataaata accagaaggc 3450

 taatcacaaa attgaggaat tagaaaaggc aaagcagcat cttgaacagg 3500

 aaatatatgt caacaaaaag cgattagaaa tggagacatt ggctacaaaa 3550

 caggctttag aagaccatag catccgccat gcaagaattc tggaagcttt 3600

 agaaactgaa aagcaaaaaa ttgctaaaga agtacaaatt ctacagcaga 3650

 atcggaataa tagggataaa acttttacag tgcagacaac ttggagctct 3700

 atgaaactct caatgatgat tcaggaagcc aatgctatca gcagcaaatt 3750

 gaaaacatac tatgtttttg gcagacatga tatatcagat aaaagtagtt 3800

 ctgacacttc tattcgggtt cgtaacctga aactaggaat ctcaacattc 3850

 tggagtctgg aaaagtttga atctaaactt gcagcaatga aagaacttta 3900

 tgagagtaat ggtagtaaca ggggtgaaga tgccttttgt gatcctgaag 3950

 atgaatggga acccgacatt acagatgcac cagtttcttc actttctaga 4000

 aggaggagta ggagtttgat gaagaacaga agaatttctg gttgtttaca 4050

 tgacatacaa gtccatccaa ttaagaattt gcattcttca cattcatcag 4100

 gtttaatgga caaatcaagc actatttact caaattcagc agagtccttt 4150

 cttcctggaa tttgcaaaga attgattggt tcttcgttag atttttttgg 4200

 acagagttat gatgaagaaa gaactatagc agacagccta attaatagtt 4250

 ttcttaaaat ttataatggg ctatttgcca tttccaaggc tcatgaagaa 4300

 caagatgaag aaagtcaaga taacttgttt tcttctgatc gagcaatcca 4350

 gtcacttact attcagactg catgtgcttt tgagcagcta gtagtgctaa 4400

 tgaaacactg gctgagtgat ttactgcctt gtaccaacat agcaagactt 4450

 gaggatgagt tgagacaaga agttaaaaaa ctgggaggct acttacagtt 4500

 atttttgcag ggatgctgtt tggatatttc atcaatgata aaagaggctc 4550

 aaaagaatgc aatccaaatt gtacaacaag ctgtaaagta tgtggggcag 4600

 ttagcagttc tgaaagggag caagctacat tttctagaaa acggtaacaa 4650

 taaagctgcc agtgtccagg aggaattcat ggatgctgtt tgtgatggtg 4700

 taggcttagg aatgaagatt ttattagatt ctggactgga aaaagcaaaa 4750

 gaacttcagc atgaactctt taggcagtgt acaaaaaatg aggttaccaa 4800

 agaaatgaaa actaatgcca tgggattgat tagatctctt gaaaacatct 4850

 ttgctgaatc gaaaattaaa agtttcagaa ggcaagtaca agaagaaaac 4900

 tttgaatacc aagatttcaa gaggatggtt aatcgtgctc cagaattctt 4950

 aaagttaaaa cattgcttag agaaagctat tgaaattatt atttctgcac 5000

 tgaaaggatg ccatagtgat ataaatcttc tccagacttg tgttgaaagt 5050

 attcgcaact tggccagtga tttttacagt gacttcagtg tgccttctac 5100

 ttctgttggc agctatgaga gtagagtaac tcacattgtc caccaggaac 5150

 tagaatctct agctaagtct ctcctctttt gttttgaatc tgaagaaagc 5200

 cctgatttgt tgaaaccctg ggaaacttat aatcaaaata ccaaagaaga 5250

 acaccaacaa tctaaatcaa gcgggattga cggcagtaag aataaaggtg 5300

 taccaaagcg tgtctatgag ctccatggct catccccagc agtgagctca 5350

 gaggaatgca cacccagtag gattcagtgg gtgtgaatac tgatgtgtag 5400

 gcacttttat gaccacccat gaaagaaaaa gaacacttgc tcggtaattt 5450

 tctttatgca ggagagttta agagaaatca gcacagatat ttcaaaaaag 5500

 tccatgtctt tttatcttta aaatatctat ttatcaaagg ccagacacag 5550

 tggctcacgc ctgtaatccc agcactttgg gaggcgggca gatcacaagg 5600

 tcaggagttt gagaccggcc tggccaacat ggtgaaaccc cgtctctact 5650

 aaaaatacaa aaatttgctg ggcatggtgg cgcgtgcctg taatcccagc 5700

 tactaggggg gctgaggcag gaggatcgct tgaacctgag aggcagaggt 5750

 tgcagtgagc caagatcatg ccactttact ccagtctgag caacagaacg 5800

 agacttagtc aaaataaata aataaataag taaataaata aataaataaa 5850

 atatctttta tctttaaagt gtttaacatt ggtatactgt ctgtagttgg 5900

 ttcattagtc gtttataaag ggttattttc tcatgagtgg aaacctgaac 5950

 aatcagttac ctttgtgcct atgccttctc tctcctcaga cagctgggat 6000

 gtttatggtg aaatggcctg tacaagttta actaagacaa cttaacttgc 6050

 attgttaatc aaaaattctt ttctcaaagg gttaactggt tgccattttg 6100

 aatagtatgt tcaagggtgt agcttcctgt ttctttccaa attataagta 6150

 gctacctaaa tatagtataa ttatatatta ataatatggc ttgctggcac 6200

 agtagtttac cctgttatct gtgtttcata atgggggctg tatgaatatt 6250

 atttaaaact aataaaatgt tgccagaatt atactaaact gttggatgag 6300

 attaggagat cagaggctgg accttctctt gataatgctt gttttgttaa 6350

 aggtataatg aaataatttg tatatgattt gatgaagatt aaagaccctt 6400

 attttccaca gctttaaaaa aaaaccttta tttatgatca agtaataaag 6450

 ataatattct acttgtggga tcttacatta tggaaatagt ttgacgtttt 6500

 tgacctcaag agtatgtata atttgaagag atactttgta actatgcttg 6550

 ggtgatattg agcagttcct aaagaataat tcattt 6586

<210> 1502
<211> 1648
<212> PRT
<213> Homo sapien

<400> 1502
 Met Ser Leu His Ser Thr His Asn Arg Asn Asn Ser Gly Asp Ile
   1               5                  10                  15

 Leu Asp Ile Pro Ser Ser Gln Asn Ser Ser Ser Leu Asn Ala Leu
                  20                  25                  30

 Thr His Ser Ser Arg Leu Lys Leu His Leu Lys Ser Asp Met Ser
                  35                  40                  45

 Glu Cys Glu Asn Asp Asp Pro Leu Leu Arg Ser Ala Gly Lys Val
                  50                  55                  60

 Arg Asp Ile Asn Arg Thr Tyr Val Ile Ser Ala Ser Arg Lys Thr
                  65                  70                  75

 Ala Asp Met Pro Leu Thr Pro Asn Pro Val Gly Arg Leu Ala Leu
                  80                  85                  90

 Gln Arg Arg Thr Thr Arg Asn Lys Glu Ser Ser Leu Leu Val Ser
                  95                 100                 105

 Glu Leu Glu Asp Thr Thr Glu Lys Thr Ala Glu Thr Arg Leu Thr
                 110                 115                 120

 Leu Gln Arg Arg Ala Lys Thr Asp Ser Ala Glu Lys Trp Lys Thr
                 125                 130                 135

 Ala Glu Ile Asp Ser Val Lys Met Thr Leu Asn Val Gly Gly Glu
                 140                 145                 150

 Thr Glu Asn Asn Gly Val Ser Lys Glu Ser Arg Thr Asn Val Arg
                 155                 160                 165

 Ile Val Asn Asn Ala Lys Asn Ser Phe Val Ala Ser Ser Val Pro
                 170                 175                 180

 Leu Asp Glu Asp Pro Gln Val Ile Glu Met Met Ala Asp Lys Lys
                 185                 190                 195

 Tyr Lys Glu Thr Phe Ser Ala Pro Ser Arg Ala Asn Glu Asn Val
                 200                 205                 210

 Ala Leu Lys Tyr Ser Ser Asn Arg Pro Pro Ile Ala Ser Leu Ser
                 215                 220                 225

 Gln Thr Glu Val Val Arg Ser Gly His Leu Thr Thr Lys Pro Thr
                 230                 235                 240

 Gln Ser Lys Leu Asp Ile Lys Val Leu Gly Thr Gly Asn Leu Tyr
                 245                 250                 255

 His Arg Ser Ile Gly Lys Glu Ile Ala Lys Thr Ser Asn Lys Phe
                 260                 265                 270

 Gly Ser Leu Glu Lys Arg Thr Pro Thr Lys Cys Thr Thr Glu His
                 275                 280                 285

 Lys Leu Thr Thr Lys Cys Ser Leu Pro Gln Leu Lys Ser Pro Ala
                 290                 295                 300

 Pro Ser Ile Leu Lys Asn Arg Met Ser Asn Leu Gln Val Lys Gln
                 305                 310                 315

 Arg Pro Lys Ser Ser Phe Leu Ala Asn Lys Gln Glu Arg Ser Ala
                 320                 325                 330

 Glu Asn Thr Ile Leu Pro Glu Glu Glu Thr Val Val Gln Asn Thr
                 335                 340                 345

 Ser Ala Gly Lys Asp Pro Leu Lys Val Glu Asn Ser Gln Val Thr
                 350                 355                 360

 Val Ala Val Arg Val Arg Pro Phe Thr Lys Arg Glu Lys Ile Glu
                 365                 370                 375

 Lys Ala Ser Gln Val Val Phe Met Ser Gly Lys Glu Ile Thr Val
                 380                 385                 390

 Glu His Pro Asp Thr Lys Gln Val Tyr Asn Phe Ile Tyr Asp Val
                 395                 400                 405

 Ser Phe Trp Ser Phe Asp Glu Cys His Pro His Tyr Ala Ser Gln
                 410                 415                 420

 Thr Thr Val Tyr Glu Lys Leu Ala Ala Pro Leu Leu Glu Arg Ala
                 425                 430                 435

 Phe Glu Gly Phe Asn Thr Cys Leu Phe Ala Tyr Gly Gln Thr Gly
                 440                 445                 450

 Ser Gly Lys Ser Tyr Thr Met Met Gly Phe Ser Glu Glu Pro Gly
                 455                 460                 465

 Ile Ile Pro Arg Phe Cys Glu Asp Leu Phe Ser Gln Val Ala Arg
                 470                 475                 480

 Lys Gln Thr Gln Glu Val Ser Tyr His Ile Glu Met Ser Phe Phe
                 485                 490                 495

 Glu Val Tyr Asn Glu Lys Ile His Asp Leu Leu Val Cys Lys Asp
                 500                 505                 510

 Glu Asn Gly Gln Arg Lys Gln Pro Leu Arg Val Arg Glu His Pro
                 515                 520                 525

 Val Tyr Gly Pro Tyr Val Glu Ala Leu Ser Met Asn Ile Val Ser
                 530                 535                 540

 Ser Tyr Ala Asp Ile Gln Ser Trp Leu Glu Leu Gly Asn Lys Gln
                 545                 550                 555

 Arg Ala Thr Ala Ala Thr Gly Met Asn Asp Lys Ser Ser Arg Ser
                 560                 565                 570

 His Ser Val Phe Thr Leu Val Met Thr Gln Thr Lys Thr Glu Phe
                 575                 580                 585

 Val Glu Gly Glu Glu His Asp His Arg Ile Thr Ser Arg Ile Asn
                 590                 595                 600

 Leu Ile Asp Leu Ala Gly Ser Glu Arg Cys Ser Thr Ala His Thr
                 605                 610                 615

 Asn Gly Asp Arg Leu Lys Glu Gly Val Ser Ile Asn Lys Ser Leu
                 620                 625                 630

 Leu Thr Leu Gly Lys Val Ile Ser Ala Leu Ser Glu Gln Ala Asn
                 635                 640                 645

 Gln Arg Ser Val Phe Ile Pro Tyr Arg Glu Ser Val Leu Thr Trp
                 650                 655                 660

 Leu Leu Lys Glu Ser Leu Gly Gly Asn Ser Lys Thr Ala Met Ile
                 665                 670                 675

 Ala Thr Ile Ser Pro Ala Ala Ser Asn Ile Glu Glu Thr Leu Ser
                 680                 685                 690

 Thr Leu Arg Tyr Ala Asn Gln Ala Arg Leu Ile Val Asn Ile Ala
                 695                 700                 705

 Lys Val Asn Glu Asp Met Asn Ala Lys Leu Ile Arg Glu Leu Lys
                 710                 715                 720

 Ala Glu Ile Ala Lys Leu Lys Ala Ala Gln Arg Asn Ser Arg Asn
                 725                 730                 735

 Ile Asp Pro Glu Arg Tyr Arg Leu Cys Arg Gln Glu Ile Thr Ser
                 740                 745                 750

 Leu Arg Met Lys Leu His Gln Gln Glu Arg Asp Met Ala Glu Met
                 755                 760                 765

 Gln Arg Val Trp Lys Glu Lys Phe Glu Gln Ala Glu Lys Arg Lys
                 770                 775                 780

 Leu Gln Glu Thr Lys Glu Leu Gln Lys Ala Gly Ile Met Phe Gln
                 785                 790                 795

 Met Asp Asn His Leu Pro Asn Leu Val Asn Leu Asn Glu Asp Pro
                 800                 805                 810

 Gln Leu Ser Glu Met Leu Leu Tyr Met Ile Lys Glu Gly Thr Thr
                 815                 820                 825

 Thr Val Gly Lys Tyr Lys Pro Asn Ser Ser His Asp Ile Gln Leu
                 830                 835                 840

 Ser Gly Val Leu Ile Ala Asp Asp His Cys Thr Ile Lys Asn Phe
                 845                 850                 855

 Gly Gly Thr Val Ser Ile Ile Pro Val Gly Glu Ala Lys Thr Tyr
                 860                 865                 870

 Val Asn Gly Lys His Ile Leu Glu Ile Thr Val Leu Arg His Gly
                 875                 880                 885

 Asp Arg Val Ile Leu Gly Gly Asp His Tyr Phe Arg Phe Asn His
                 890                 895                 900

 Pro Val Glu Val Gln Lys Gly Lys Arg Pro Ser Gly Arg Asp Thr
                 905                 910                 915

 Pro Ile Ser Glu Gly Pro Lys Asp Phe Glu Phe Ala Lys Asn Glu
                 920                 925                 930

 Leu Leu Met Ala Gln Arg Ser Gln Leu Glu Ala Glu Ile Lys Glu
                 935                 940                 945

 Ala Gln Leu Lys Ala Lys Glu Glu Met Met Gln Gly Ile Gln Ile
                 950                 955                 960

 Ala Lys Glu Met Ala Gln Gln Glu Leu Ser Ser Gln Lys Ala Ala
                 965                 970                 975

 Tyr Glu Ser Lys Ile Lys Ala Leu Glu Ala Glu Leu Arg Glu Glu
                 980                 985                 990

 Ser Gln Arg Lys Lys Met Gln Glu Ile Asn Asn Gln Lys Ala Asn
                 995                1000                1005

 His Lys Ile Glu Glu Leu Glu Lys Ala Lys Gln His Leu Glu Gln
                1010                1015                1020

 Glu Ile Tyr Val Asn Lys Lys Arg Leu Glu Met Glu Thr Leu Ala
                1025                1030                1035

 Thr Lys Gln Ala Leu Glu Asp His Ser Ile Arg His Ala Arg Ile
                1040                1045                1050

 Leu Glu Ala Leu Glu Thr Glu Lys Gln Lys Ile Ala Lys Glu Val
                1055                1060                1065

 Gln Ile Leu Gln Gln Asn Arg Asn Asn Arg Asp Lys Thr Phe Thr
                1070                1075                1080

 Val Gln Thr Thr Trp Ser Ser Met Lys Leu Ser Met Met Ile Gln
                1085                1090                1095

 Glu Ala Asn Ala Ile Ser Ser Lys Leu Lys Thr Tyr Tyr Val Phe
                1100                1105                1110

 Gly Arg His Asp Ile Ser Asp Lys Ser Ser Ser Asp Thr Ser Ile
                1115                1120                1125

 Arg Val Arg Asn Leu Lys Leu Gly Ile Ser Thr Phe Trp Ser Leu
                1130                1135                1140

 Glu Lys Phe Glu Ser Lys Leu Ala Ala Met Lys Glu Leu Tyr Glu
                1145                1150                1155

 Ser Asn Gly Ser Asn Arg Gly Glu Asp Ala Phe Cys Asp Pro Glu
                1160                1165                1170

 Asp Glu Trp Glu Pro Asp Ile Thr Asp Ala Pro Val Ser Ser Leu
                1175                1180                1185

 Ser Arg Arg Arg Ser Arg Ser Leu Met Lys Asn Arg Arg Ile Ser
                1190                1195                1200

 Gly Cys Leu His Asp Ile Gln Val His Pro Ile Lys Asn Leu His
                1205                1210                1215

 Ser Ser His Ser Ser Gly Leu Met Asp Lys Ser Ser Thr Ile Tyr
                1220                1225                1230

 Ser Asn Ser Ala Glu Ser Phe Leu Pro Gly Ile Cys Lys Glu Leu
                1235                1240                1245

 Ile Gly Ser Ser Leu Asp Phe Phe Gly Gln Ser Tyr Asp Glu Glu
                1250                1255                1260

 Arg Thr Ile Ala Asp Ser Leu Ile Asn Ser Phe Leu Lys Ile Tyr
                1265                1270                1275

 Asn Gly Leu Phe Ala Ile Ser Lys Ala His Glu Glu Gln Asp Glu
                1280                1285                1290

 Glu Ser Gln Asp Asn Leu Phe Ser Ser Asp Arg Ala Ile Gln Ser
                1295                1300                1305

 Leu Thr Ile Gln Thr Ala Cys Ala Phe Glu Gln Leu Val Val Leu
                1310                1315                1320

 Met Lys His Trp Leu Ser Asp Leu Leu Pro Cys Thr Asn Ile Ala
                1325                1330                1335

 Arg Leu Glu Asp Glu Leu Arg Gln Glu Val Lys Lys Leu Gly Gly
                1340                1345                1350

 Tyr Leu Gln Leu Phe Leu Gln Gly Cys Cys Leu Asp Ile Ser Ser
                1355                1360                1365

 Met Ile Lys Glu Ala Gln Lys Asn Ala Ile Gln Ile Val Gln Gln
                1370                1375                1380

 Ala Val Lys Tyr Val Gly Gln Leu Ala Val Leu Lys Gly Ser Lys
                1385                1390                1395

 Leu His Phe Leu Glu Asn Gly Asn Asn Lys Ala Ala Ser Val Gln
                1400                1405                1410

 Glu Glu Phe Met Asp Ala Val Cys Asp Gly Val Gly Leu Gly Met
                1415                1420                1425

 Lys Ile Leu Leu Asp Ser Gly Leu Glu Lys Ala Lys Glu Leu Gln
                1430                1435                1440

 His Glu Leu Phe Arg Gln Cys Thr Lys Asn Glu Val Thr Lys Glu
                1445                1450                1455

 Met Lys Thr Asn Ala Met Gly Leu Ile Arg Ser Leu Glu Asn Ile
                1460                1465                1470

 Phe Ala Glu Ser Lys Ile Lys Ser Phe Arg Arg Gln Val Gln Glu
                1475                1480                1485

 Glu Asn Phe Glu Tyr Gln Asp Phe Lys Arg Met Val Asn Arg Ala
                1490                1495                1500

 Pro Glu Phe Leu Lys Leu Lys His Cys Leu Glu Lys Ala Ile Glu
                1505                1510                1515

 Ile Ile Ile Ser Ala Leu Lys Gly Cys His Ser Asp Ile Asn Leu
                1520                1525                1530

 Leu Gln Thr Cys Val Glu Ser Ile Arg Asn Leu Ala Ser Asp Phe
                1535                1540                1545

 Tyr Ser Asp Phe Ser Val Pro Ser Thr Ser Val Gly Ser Tyr Glu
                1550                1555                1560

 Ser Arg Val Thr His Ile Val His Gln Glu Leu Glu Ser Leu Ala
                1565                1570                1575

 Lys Ser Leu Leu Phe Cys Phe Glu Ser Glu Glu Ser Pro Asp Leu
                1580                1585                1590

 Leu Lys Pro Trp Glu Thr Tyr Asn Gln Asn Thr Lys Glu Glu His
                1595                1600                1605

 Gln Gln Ser Lys Ser Ser Gly Ile Asp Gly Ser Lys Asn Lys Gly
                1610                1615                1620

 Val Pro Lys Arg Val Tyr Glu Leu His Gly Ser Ser Pro Ala Val
                1625                1630                1635

 Ser Ser Glu Glu Cys Thr Pro Ser Arg Ile Gln Trp Val
                1640                1645

<210> 1503
<211> 1222
<212> DNA
<213> Homo sapien

<400> 1503
 agctcagcag gacctcagcc atgagacttc tcatcctggc cctccttggc 50

 atctgctctc tcactgcata cattgtggaa ggtgtaggga gtgaagtctc 100

 agataagagg acctgtgtga gcctcactac ccagcgactg ccggttagca 150

 gaatcaagac ctacaccatc acggaaggct ccttgagagc agtaattttt 200

 attaccaaac gtggcctaaa agtctgtgct gatccacaag ccacatgggt 250

 gagagacgtg gtcaggagca tggacaggaa atccaacacc agaaataaca 300

 tgatccagac caagccaaca ggaacccagc aatcgaccaa tacagctgtg 350

 actctgactg gctagtagtc tctggcaccc tgtccgtctc cagccagcca 400

 gctcatttca ctttacacgc tcatggactg agtttatact caccttttat 450

 gaaagcactg catgaataaa attattcctt tgtattttta cttttaaatg 500

 tcttctgtat tcacttatat gttctaatta ataaattatt tattattaag 550

 aatagttccc tagtctattc attatattta gggaaaggta gtgtatcatt 600

 gttgtttgat ttctgacctt gtacctctct ttgatggtaa ccataatgga 650

 agagattctg gctagtgtct atcagaggtg aaagctatat caatctctct 700

 tagagtccag cttgtaatgg ttctttacac atcagtcaca agttacagct 750

 gtgacaatgg caacaatttg agatgtattt caacttgtct ctataataga 800

 attctgttta tagaataagg gagaaaataa tccagtcttc actgggttcc 850

 cattctgagg gtccactact caaaaatttg cttcactcaa tttttttcac 900

 ctctttgtgt tttattttgg tgtcctatta aaggaataaa atgacacaac 950

 ttgtcccttt tttgtcccat tagcaaaaat tagaattttg gtataaagaa 1000

 actttattca agtaaaaatc aatacccttt gaattggaca ataatctcac 1050

 taccttatta ggatttctgt atttgccatt acgctagtta tcatgcatgt 1100

 tatgctttac tgcgaataag cttttaatgc tccaaatgct gacccatgca 1150

 atatttcctc atgtgatcac aatttgcagt aaacttttaa ttaaatgctc 1200

 atctggtaac tcaacacccc ag 1222

<210> 1504
<211> 114
<212> PRT
<213> Homo sapien

<400> 1504
 Met Arg Leu Leu Ile Leu Ala Leu Leu Gly Ile Cys Ser Leu Thr
   1               5                  10                  15

 Ala Tyr Ile Val Glu Gly Val Gly Ser Glu Val Ser Asp Lys Arg
                  20                  25                  30

 Thr Cys Val Ser Leu Thr Thr Gln Arg Leu Pro Val Ser Arg Ile
                  35                  40                  45

 Lys Thr Tyr Thr Ile Thr Glu Gly Ser Leu Arg Ala Val Ile Phe
                  50                  55                  60

 Ile Thr Lys Arg Gly Leu Lys Val Cys Ala Asp Pro Gln Ala Thr
                  65                  70                  75

 Trp Val Arg Asp Val Val Arg Ser Met Asp Arg Lys Ser Asn Thr
                  80                  85                  90

 Arg Asn Asn Met Ile Gln Thr Lys Pro Thr Gly Thr Gln Gln Ser
                  95                 100                 105

 Thr Asn Thr Ala Val Thr Leu Thr Gly
                 110

<210> 1505
<211> 1222
<212> DNA
<213> Homo sapien

<400> 1505
 agctcagcag gacctcagcc atgagacttc tcatcctggc cctccttggc 50

 atctgctctc tcactgcata cattgtggaa ggtgtaggga gtgaagtctc 100

 agataagagg acctgtgtga gcctcactac ccagcgactg ccggttagca 150

 gaatcaagac ctacaccatc acggaaggct ccttgagagc agtaattttt 200

 attaccaaac gtggcctaaa agtctgtgct gatccacaag ccacatgggt 250

 gagagacgtg gtcaggagca tggacaggaa atccaacacc agaaataaca 300

 tgatccagac caagccaaca ggaacccagc aatcgaccaa tacagctgtg 350

 actctgactg gctagtagtc tctggcaccc tgtccgtctc cagccagcca 400

 gctcatttca ctttacacgc tcatggactg agtttatact caccttttat 450

 gaaagcactg catgaataaa attattcctt tgtattttta cttttaaatg 500

 tcttctgtat tcacttatat gttctaatta ataaattatt tattattaag 550

 aatagttccc tagtctattc attatattta gggaaaggta gtgtatcatt 600

 gttgtttgat ttctgacctt gtacctctct ttgatggtaa ccataatgga 650

 agagattctg gctagtgtct atcagaggtg aaagctatat caatctctct 700

 tagagtccag cttgtaatgg ttctttacac atcagtcaca agttacagct 750

 gtgacaatgg caacaatttg agatgtattt caacttgtct ctataataga 800

 attctgttta tagaataagg gagaaaataa tccagtcttc actgggttcc 850

 cattctgagg gtccactact caaaaatttg cttcactcaa tttttttcac 900

 ctctttgtgt tttattttgg tgtcctatta aaggaataaa atgacacaac 950

 ttgtcccttt tttgtcccat tagcaaaaat tagaattttg gtataaagaa 1000

 actttattca agtaaaaatc aatacccttt gaattggaca ataatctcac 1050

 taccttatta ggatttctgt atttgccatt acgctagtta tcatgcatgt 1100

 tatgctttac tgcgaataag cttttaatgc tccaaatgct gacccatgca 1150

 atatttcctc atgtgatcac aatttgcagt aaacttttaa ttaaatgctc 1200

 atctggtaac tcaacacccc ag 1222

<210> 1506
<211> 114
<212> PRT
<213> Homo sapien

<400> 1506
 Met Arg Leu Leu Ile Leu Ala Leu Leu Gly Ile Cys Ser Leu Thr
   1               5                  10                  15

 Ala Tyr Ile Val Glu Gly Val Gly Ser Glu Val Ser Asp Lys Arg
                  20                  25                  30

 Thr Cys Val Ser Leu Thr Thr Gln Arg Leu Pro Val Ser Arg Ile
                  35                  40                  45

 Lys Thr Tyr Thr Ile Thr Glu Gly Ser Leu Arg Ala Val Ile Phe
                  50                  55                  60

 Ile Thr Lys Arg Gly Leu Lys Val Cys Ala Asp Pro Gln Ala Thr
                  65                  70                  75

 Trp Val Arg Asp Val Val Arg Ser Met Asp Arg Lys Ser Asn Thr
                  80                  85                  90

 Arg Asn Asn Met Ile Gln Thr Lys Pro Thr Gly Thr Gln Gln Ser
                  95                 100                 105

 Thr Asn Thr Ala Val Thr Leu Thr Gly
                 110

<210> 1507
<211> 5379
<212> DNA
<213> Homo sapien

<400> 1507
 gcacttcctt ctcggctaga ttatctgaaa ctgttgtcgg ttcttgagat 50

 gatactacca ccgaatgtct gtgtttcatt gtctagtcca acctgtattg 100

 tggatatcta caacgttccg gcaatagttt tgcaggtgca tcacattttt 150

 gtttttgttt tgggaggaaa agggagggca cggcagccag gcttcatatt 200

 cctacaagtg catgcttcaa gattactgta cttacagtgt ttccaacatc 250

 ttctcataaa aggggaaagc ttcatagcct caaccatgaa ggaaaccagt 300

 cgcatagggc atggagctgg agaactataa acagcccgtg gtgctgagag 350

 aggacaactg ccgaaggcgc cggaggatga agccgcgcag tgctgcggcc 400

 agcctgtcct ccatggagct catccccatc gagttcgtgc tgcccaccag 450

 ccagcgcaaa tgcaagagcc ccgaaacggc gctgctgcac gtggccggcc 500

 acggcaacgt ggagcagatg aaggcccagg tgtggctgcg agcgctggag 550

 accagcgtgg cggcggactt ctaccaccgg ctgggaccgc atcacttcct 600

 cctgctctat cagaagaagg ggcagtggta cgagatctac gacaagtacc 650

 aggtggtgca gactctggac tgcctgcgct actggaaggc cacgcaccgg 700

 agcccgggcc agatccacct ggtgcagcgg cacccgccct ccgaggagtc 750

 ccaagccttc cagcggcagc tcacggcgct gattggctat gacgtcactg 800

 acgtcagcaa cgtgcacgac gatgagctgg agttcacgcg ccgtggcttg 850

 gtgaccccgc gcatggcgga ggtggccagc cgcgacccca agctctacgc 900

 catgcacccg tgggtgacgt ccaagcccct cccggagtac ctgtggaaga 950

 agattgccaa caactgcatc ttcatcgtca ttcaccgcag caccaccagc 1000

 cagaccatta aggtctcacc cgacgacacc cccggcgcca tcctgcagag 1050

 cttcttcacc aagatggcca agaagaaatc tctgatggat attcccgaaa 1100

 gccaaagcga acaggatttt gtgctgcgcg tctgtggccg ggatgagtac 1150

 ctggtgggcg aaacgcccat caaaaacttc cagtgggtga ggcactgcct 1200

 caagaacgga gaagagattc acgtggtact ggacacgcct ccagacccgg 1250

 ccctagacga ggtgaggaag gaagagtggc cgctggtgga tgactgcacg 1300

 ggagtcaccg gctaccatga gcagcttacc atccacggca aggaccacga 1350

 gagtgtgttc accgtgtccc tgtgggactg cgaccgcaag ttcagggtca 1400

 agatcagagg cattgatatc cccgtcctgc ctcggaacac cgacctcaca 1450

 gtttttgtag aggcaaacat ccagcatggg caacaagtcc tttgccaaag 1500

 gagaaccagc cccaaaccct tcacagagga ggtgctgtgg aatgtgtggc 1550

 ttgagttcag tatcaaaatc aaagacttgc ccaaaggggc tctactgaac 1600

 ctccagatct actgcggtaa agctccagca ctgtccagca aggcctctgc 1650

 agagtccccc agttctgagt ccaagggcaa agttcagctt ctctattatg 1700

 tgaacctgct gctgatagac caccgtttcc tcctgcgccg tggagaatac 1750

 gtcctccaca tgtggcagat atctgggaag ggagaagacc aaggaagctt 1800

 caatgctgac aaactcacgt ctgcaactaa cccagacaag gagaactcaa 1850

 tgtccatctc cattcttctg gacaattact gccacccgat agccctgcct 1900

 aagcatcagc ccacccctga cccggaaggg gaccgggttc gagcagaaat 1950

 gcccaaccag cttcgcaagc aattggaggc gatcatagcc actgatccac 2000

 ttaaccctct cacagcagag gacaaagaat tgctctggca ttttagatac 2050

 gaaagcctta agcacccaaa agcatatcct aagctattta gttcagtgaa 2100

 atggggacag caagaaattg tggccaaaac ataccaattg ttggccagaa 2150

 gggaagtctg ggatcaaagt gctttggatg ttgggttaac aatgcagctc 2200

 ctggactgca acttctcaga tgaaaatgta agagccattg cagttcagaa 2250

 actggagagc ttggaggacg atgatgttct gcattacctt ctacaattgg 2300

 tccaggctgt gaaatttgaa ccataccatg atagcgccct tgccagattt 2350

 ctgctgaagc gtggtttaag aaacaaaaga attggtcact ttttgttttg 2400

 gttcttgaga agtgagatag cccagtccag acactatcag cagaggttcg 2450

 ctgtgattct ggaagcctat ctgaggggct gtggcacagc catgctgcac 2500

 gactttaccc aacaagtcca agtaatcgag atgttacaaa aagtcaccct 2550

 tgatattaaa tcgctctctg ctgaaaagta tgacgtcagt tcccaagtta 2600

 tttcacaact taaacaaaag cttgaaaacc tgcagaattc tcaactcccc 2650

 gaaagcttta gagttccata tgatcctgga ctgaaagcag gagcgctggc 2700

 aattgaaaaa tgtaaagtaa tggcctccaa gaaaaaacca ctatggcttg 2750

 agtttaaatg tgccgatcct acagccctat caaatgaaac aattggaatt 2800

 atctttaaac atggtgatga tctgcgccaa gacatgctta ttttacagat 2850

 tctacgaatc atggagtcta tttgggagac tgaatctttg gatctatgcc 2900

 tcctgccata tggttgcatt tcaactggtg acaaaatagg aatgatcgag 2950

 attgtgaaag acgccacgac aattgccaaa attcagcaaa gcacagtggg 3000

 caacacggga gcatttaaag atgaagtcct gaatcactgg ctcaaagaaa 3050

 aatcccctac tgaagaaaag tttcaggcag cagtggagag atttgtttat 3100

 tcctgtgcag gctactgtgt ggcaaccttt gttcttggaa taggcgacag 3150

 acacaatgac aatattatga tcaccgagac aggaaaccta tttcatattg 3200

 acttcgggca cattcttggg aattacaaaa gtttcctggg cattaataaa 3250

 gagagagtgc catttgtgct aacccctgac ttcctctttg tgatgggaac 3300

 ttctggaaag aagacaagcc cacacttcca gaaatttcag gacatctgtg 3350

 ttaaggctta tctagccctt cgtcatcaca caaacctact gatcatcctg 3400

 ttctccatga tgctgatgac aggaatgccc cagttaacaa gcaaagaaga 3450

 cattgaatat atccgggatg ccctcacagt ggggaaaaat gaggaggatg 3500

 ctaaaaagta ttttcttgat cagatcgaag tttgcagaga caaaggatgg 3550

 actgtgcagt ttaattggtt tctacatctt gttcttggca tcaaacaagg 3600

 agagaaacat tcagcctaat actttaggct agaatcaaaa acaagttagt 3650

 gttctatggt ttaaattagc atagcaatca tcgaacttgg atttcaaatg 3700

 caatagacat tgtgaaagct ggcatttcag aagtatagct cttttcctac 3750

 ctgaactctt ccctggagaa aagatgttgg cattgctgat tgtttggtta 3800

 agcaatgtcc agtgctagga ttatttgcag gtttggtttt ttctcatttg 3850

 tctgtggcat tggagaatat tctcggttta aacagactaa tgacttcctt 3900

 attgtccctg atattttgac tatcttacta ttgagtgctt ctggaaattc 3950

 tttggaataa ttgatgacat ctattttcat ctgggtttag tctcaatttt 4000

 ggttatcttt gtgttcctca agctctttaa agaaaaagat gtaatcgttg 4050

 taacctttgt ctcattcctt aaatgatgct tccaaacatc tccttagtgt 4100

 ctgcaggtgt tagtggtgtg ctaaaagcaa ggaaagcgag ttagtctttt 4150

 cagtgtcttt tgcaattcaa ttcttttgtc atgtataact gagacacaca 4200

 aacacagcag gagaaatcta aaccgttgtg ccttgacctt cctctgctgg 4250

 tcttgttcca gggttatgaa tatgaaaaaa tagagatgag actttttgtg 4300

 tcaactctgt ccacaagagt gagttatcta gtatgattag tatagctttc 4350

 tccagcatgg cagcaggaag taactacagg gcctctttta tgcctgacat 4400

 ttcttccctt cctttttccc tgcctccctt tttcatcaat tgcaatgctc 4450

 ccacaactct ttacagactt gtgaaatctt caagaacacc tttactctat 4500

 aactcaaaaa ttagttgaaa aataattact tctcaaggat tattagaatc 4550

 ttaggtactt atttgtaaag atgtttagtg actttttttt caagtatctt 4600

 attaaaggag gcattctaga aaatatgaat tagtttccaa atgccttaat 4650

 tttaaacttt ggcctgaaca gttttttctt tttcttaatg gaagaagata 4700

 tttaatatct taaaaatatt ccaagttagg aagaacacta cttgccttat 4750

 ccatttccca tttaaaggac ttttaaactt tgacacatcc ttcagatttc 4800

 ctgaaaataa ttgaaatatc ttactttaaa aatattttca tctctgaaat 4850

 atctcgttat ttattggagg tattgtttaa ccttagagag accattaaat 4900

 tatttataaa atattttgta attacctgta gctaatacat tacatagaaa 4950

 aaaactatgt taacagtgtc tctgtttaag tataatcaga tataaatata 5000

 tacttaattt tttaatttta aaaatagata cctgtttgac tttgaggtag 5050

 tccagacctt ttcttttttt tttttttttt aatgtgtgca aaagcccaaa 5100

 ggttcctaag cctggctgca aagaagaatc aacagggaca ctttttaaaa 5150

 acactcttat cagcctgggc aacacagtga gactccatct cttaaaaaaa 5200

 aaattagctg ggtatagtgg tatgtgcctg tagtcccagg tactcaggag 5250

 gctgaggcag gaggattgcc tgagcccagg aggtggaaac tgcagagagt 5300

 catgatcatg tccttacact ccagcctgga taacagagcg agaccctgtc 5350

 tcaaaaaaat aaaataaaaa ataaaaaca 5379

<210> 1508
<211> 1102
<212> PRT
<213> Homo sapien

<400> 1508
 Met Glu Leu Glu Asn Tyr Lys Gln Pro Val Val Leu Arg Glu Asp
   1               5                  10                  15

 Asn Cys Arg Arg Arg Arg Arg Met Lys Pro Arg Ser Ala Ala Ala
                  20                  25                  30

 Ser Leu Ser Ser Met Glu Leu Ile Pro Ile Glu Phe Val Leu Pro
                  35                  40                  45

 Thr Ser Gln Arg Lys Cys Lys Ser Pro Glu Thr Ala Leu Leu His
                  50                  55                  60

 Val Ala Gly His Gly Asn Val Glu Gln Met Lys Ala Gln Val Trp
                  65                  70                  75

 Leu Arg Ala Leu Glu Thr Ser Val Ala Ala Asp Phe Tyr His Arg
                  80                  85                  90

 Leu Gly Pro His His Phe Leu Leu Leu Tyr Gln Lys Lys Gly Gln
                  95                 100                 105

 Trp Tyr Glu Ile Tyr Asp Lys Tyr Gln Val Val Gln Thr Leu Asp
                 110                 115                 120

 Cys Leu Arg Tyr Trp Lys Ala Thr His Arg Ser Pro Gly Gln Ile
                 125                 130                 135

 His Leu Val Gln Arg His Pro Pro Ser Glu Glu Ser Gln Ala Phe
                 140                 145                 150

 Gln Arg Gln Leu Thr Ala Leu Ile Gly Tyr Asp Val Thr Asp Val
                 155                 160                 165

 Ser Asn Val His Asp Asp Glu Leu Glu Phe Thr Arg Arg Gly Leu
                 170                 175                 180

 Val Thr Pro Arg Met Ala Glu Val Ala Ser Arg Asp Pro Lys Leu
                 185                 190                 195

 Tyr Ala Met His Pro Trp Val Thr Ser Lys Pro Leu Pro Glu Tyr
                 200                 205                 210

 Leu Trp Lys Lys Ile Ala Asn Asn Cys Ile Phe Ile Val Ile His
                 215                 220                 225

 Arg Ser Thr Thr Ser Gln Thr Ile Lys Val Ser Pro Asp Asp Thr
                 230                 235                 240

 Pro Gly Ala Ile Leu Gln Ser Phe Phe Thr Lys Met Ala Lys Lys
                 245                 250                 255

 Lys Ser Leu Met Asp Ile Pro Glu Ser Gln Ser Glu Gln Asp Phe
                 260                 265                 270

 Val Leu Arg Val Cys Gly Arg Asp Glu Tyr Leu Val Gly Glu Thr
                 275                 280                 285

 Pro Ile Lys Asn Phe Gln Trp Val Arg His Cys Leu Lys Asn Gly
                 290                 295                 300

 Glu Glu Ile His Val Val Leu Asp Thr Pro Pro Asp Pro Ala Leu
                 305                 310                 315

 Asp Glu Val Arg Lys Glu Glu Trp Pro Leu Val Asp Asp Cys Thr
                 320                 325                 330

 Gly Val Thr Gly Tyr His Glu Gln Leu Thr Ile His Gly Lys Asp
                 335                 340                 345

 His Glu Ser Val Phe Thr Val Ser Leu Trp Asp Cys Asp Arg Lys
                 350                 355                 360

 Phe Arg Val Lys Ile Arg Gly Ile Asp Ile Pro Val Leu Pro Arg
                 365                 370                 375

 Asn Thr Asp Leu Thr Val Phe Val Glu Ala Asn Ile Gln His Gly
                 380                 385                 390

 Gln Gln Val Leu Cys Gln Arg Arg Thr Ser Pro Lys Pro Phe Thr
                 395                 400                 405

 Glu Glu Val Leu Trp Asn Val Trp Leu Glu Phe Ser Ile Lys Ile
                 410                 415                 420

 Lys Asp Leu Pro Lys Gly Ala Leu Leu Asn Leu Gln Ile Tyr Cys
                 425                 430                 435

 Gly Lys Ala Pro Ala Leu Ser Ser Lys Ala Ser Ala Glu Ser Pro
                 440                 445                 450

 Ser Ser Glu Ser Lys Gly Lys Val Gln Leu Leu Tyr Tyr Val Asn
                 455                 460                 465

 Leu Leu Leu Ile Asp His Arg Phe Leu Leu Arg Arg Gly Glu Tyr
                 470                 475                 480

 Val Leu His Met Trp Gln Ile Ser Gly Lys Gly Glu Asp Gln Gly
                 485                 490                 495

 Ser Phe Asn Ala Asp Lys Leu Thr Ser Ala Thr Asn Pro Asp Lys
                 500                 505                 510

 Glu Asn Ser Met Ser Ile Ser Ile Leu Leu Asp Asn Tyr Cys His
                 515                 520                 525

 Pro Ile Ala Leu Pro Lys His Gln Pro Thr Pro Asp Pro Glu Gly
                 530                 535                 540

 Asp Arg Val Arg Ala Glu Met Pro Asn Gln Leu Arg Lys Gln Leu
                 545                 550                 555

 Glu Ala Ile Ile Ala Thr Asp Pro Leu Asn Pro Leu Thr Ala Glu
                 560                 565                 570

 Asp Lys Glu Leu Leu Trp His Phe Arg Tyr Glu Ser Leu Lys His
                 575                 580                 585

 Pro Lys Ala Tyr Pro Lys Leu Phe Ser Ser Val Lys Trp Gly Gln
                 590                 595                 600

 Gln Glu Ile Val Ala Lys Thr Tyr Gln Leu Leu Ala Arg Arg Glu
                 605                 610                 615

 Val Trp Asp Gln Ser Ala Leu Asp Val Gly Leu Thr Met Gln Leu
                 620                 625                 630

 Leu Asp Cys Asn Phe Ser Asp Glu Asn Val Arg Ala Ile Ala Val
                 635                 640                 645

 Gln Lys Leu Glu Ser Leu Glu Asp Asp Asp Val Leu His Tyr Leu
                 650                 655                 660

 Leu Gln Leu Val Gln Ala Val Lys Phe Glu Pro Tyr His Asp Ser
                 665                 670                 675

 Ala Leu Ala Arg Phe Leu Leu Lys Arg Gly Leu Arg Asn Lys Arg
                 680                 685                 690

 Ile Gly His Phe Leu Phe Trp Phe Leu Arg Ser Glu Ile Ala Gln
                 695                 700                 705

 Ser Arg His Tyr Gln Gln Arg Phe Ala Val Ile Leu Glu Ala Tyr
                 710                 715                 720

 Leu Arg Gly Cys Gly Thr Ala Met Leu His Asp Phe Thr Gln Gln
                 725                 730                 735

 Val Gln Val Ile Glu Met Leu Gln Lys Val Thr Leu Asp Ile Lys
                 740                 745                 750

 Ser Leu Ser Ala Glu Lys Tyr Asp Val Ser Ser Gln Val Ile Ser
                 755                 760                 765

 Gln Leu Lys Gln Lys Leu Glu Asn Leu Gln Asn Ser Gln Leu Pro
                 770                 775                 780

 Glu Ser Phe Arg Val Pro Tyr Asp Pro Gly Leu Lys Ala Gly Ala
                 785                 790                 795

 Leu Ala Ile Glu Lys Cys Lys Val Met Ala Ser Lys Lys Lys Pro
                 800                 805                 810

 Leu Trp Leu Glu Phe Lys Cys Ala Asp Pro Thr Ala Leu Ser Asn
                 815                 820                 825

 Glu Thr Ile Gly Ile Ile Phe Lys His Gly Asp Asp Leu Arg Gln
                 830                 835                 840

 Asp Met Leu Ile Leu Gln Ile Leu Arg Ile Met Glu Ser Ile Trp
                 845                 850                 855

 Glu Thr Glu Ser Leu Asp Leu Cys Leu Leu Pro Tyr Gly Cys Ile
                 860                 865                 870

 Ser Thr Gly Asp Lys Ile Gly Met Ile Glu Ile Val Lys Asp Ala
                 875                 880                 885

 Thr Thr Ile Ala Lys Ile Gln Gln Ser Thr Val Gly Asn Thr Gly
                 890                 895                 900

 Ala Phe Lys Asp Glu Val Leu Asn His Trp Leu Lys Glu Lys Ser
                 905                 910                 915

 Pro Thr Glu Glu Lys Phe Gln Ala Ala Val Glu Arg Phe Val Tyr
                 920                 925                 930

 Ser Cys Ala Gly Tyr Cys Val Ala Thr Phe Val Leu Gly Ile Gly
                 935                 940                 945

 Asp Arg His Asn Asp Asn Ile Met Ile Thr Glu Thr Gly Asn Leu
                 950                 955                 960

 Phe His Ile Asp Phe Gly His Ile Leu Gly Asn Tyr Lys Ser Phe
                 965                 970                 975

 Leu Gly Ile Asn Lys Glu Arg Val Pro Phe Val Leu Thr Pro Asp
                 980                 985                 990

 Phe Leu Phe Val Met Gly Thr Ser Gly Lys Lys Thr Ser Pro His
                 995                1000                1005

 Phe Gln Lys Phe Gln Asp Ile Cys Val Lys Ala Tyr Leu Ala Leu
                1010                1015                1020

 Arg His His Thr Asn Leu Leu Ile Ile Leu Phe Ser Met Met Leu
                1025                1030                1035

 Met Thr Gly Met Pro Gln Leu Thr Ser Lys Glu Asp Ile Glu Tyr
                1040                1045                1050

 Ile Arg Asp Ala Leu Thr Val Gly Lys Asn Glu Glu Asp Ala Lys
                1055                1060                1065

 Lys Tyr Phe Leu Asp Gln Ile Glu Val Cys Arg Asp Lys Gly Trp
                1070                1075                1080

 Thr Val Gln Phe Asn Trp Phe Leu His Leu Val Leu Gly Ile Lys
                1085                1090                1095

 Gln Gly Glu Lys His Ser Ala
                1100

<210> 1509
<211> 14770
<212> DNA
<213> Homo sapien

<400> 1509
 gggacaccat catttgggtt tttaaaagct tcagcttctc cagcatcttt 50

 gcattgtgaa tatcttcctg cttctagtca aagctttctc tctagtgatt 100

 ggaatgctgc tgtaagccta ttagaggtgc ctgaggatat caccttttac 150

 aaggaagccg tgtgtgcttg agaggatctt tttaaatgca ttatggctca 200

 tgcagcctca caattaaaga aaaacaggga tttagaaatc aatgctgaag 250

 aagagcctga gaaaaaaagg aaacaccgca aacggtcccg ggatcggaag 300

 aaaaagtctg atgccaatgc aagttactta agagcagctc gagctggaca 350

 ccttgaaaag gccctcgact acataaaaaa tggagttgac atcaacattt 400

 gcaatcagaa tgggttgaac gctctccacc ttgcttccaa agaaggccat 450

 gtagaggttg tttctgagct gctgcagaga gaagccaatg tggatgcagc 500

 tacaaagaaa ggaaacacag cattgcacat cgcatctttg gctgggcaag 550

 cagaggtggt aaaagtcttg gttacaaatg gagccaatgt caatgcacaa 600

 tctcagaatg gtttcacgcc attgtatatg gcagcccagg aaaatcacct 650

 ggaagttgtc aagtttcttc ttgacaatgg tgcaagccag agcctagcca 700

 cagaggatgg cttcacacca ttggcagtgg ctttgcaaca aggtcacgac 750

 caagtcgttt cgctcctgct agagaatgac accaaaggaa aagtgcgtct 800

 cccagctctt catatcgcgg cccgcaaaga cgacacaaaa gccgccgccc 850

 tgctgctgca gaatgacaac aatgcagatg tggaatcaaa gagtggcttc 900

 actccgctcc acatagctgc tcactatgga aatatcaatg tagccacgtt 950

 gctgttaaac cgagcggctg ctgtggattt caccgcaagg aatgacatca 1000

 ctcctttaca tgttgcatca aaaagaggaa atgcaaatat ggtaaaacta 1050

 ttgctcgatc gaggagctaa aatcgatgcc aaaaccaggg atggtctgac 1100

 accactgcac tgtggagcaa ggagtggcca cgagcaggtg gtagaaatgt 1150

 tgcttgatcg agctgccccc attctttcaa aaaccaagaa tggattatct 1200

 ccattgcaca tggccacaca aggggatcat ttaaactgcg tccagcttct 1250

 cctccagcat aatgtacccg tggatgatgt caccaatgac tacctgactg 1300

 ccctacacgt ggctgcccac tgtggccatt acaaagttgc caaggttctc 1350

 ttggataaga aagctaaccc caatgccaaa gccctgaatg gctttacccc 1400

 tcttcatatc gcctgcaaga agaatcgaat taaagtaatg gaactccttc 1450

 tgaaacacgg tgcatccatc caagctgtaa ccgagtcggg ccttacccca 1500

 atccatgttg ctgccttcat ggggcatgta aatattgtat cacaactaat 1550

 gcatcatgga gcctcaccaa acaccaccaa tgtgagagga gaaacagcac 1600

 tgcacatggc agctcgctcc ggccaagctg aagttgtgcg gtatctggta 1650

 caagacggag ctcaggtaga agctaaagct aaggatgacc aaacaccact 1700

 ccacatttca gcccgactgg ggaaagcaga catagtacaa cagctgttgc 1750

 agcaaggggc atctccaaat gcagccacaa cttctgggta caccccactt 1800

 cacctttccg cccgagaggg gcatgaggat gtggccgcgt tccttttgga 1850

 tcatggagcg tctttatcta taacaacaaa gaaaggattt actcctcttc 1900

 atgtggcagc aaaatatgga aagcttgaag tcgccaatct cctgctacag 1950

 aaaagtgcat ctccagatgc tgctgggaag agcgggctaa caccactgca 2000

 tgtagctgca cattacgata atcagaaagt ggcccttctg cttttggacc 2050

 aaggagcctc acctcacgca gccgcaaaga atggttatac gccactgcac 2100

 atcgctgcca aaaagaacca gatggacata gcgacaactc tgctggaata 2150

 tggtgctgat gccaacgcag ttacccggca aggaattgct tccgtccatc 2200

 tcgcagctca ggaagggcac gtggacatgg tgtcgctgct cctcggtaga 2250

 aatgcgaatg tgaacctgag caataagagc ggcctgaccc cactccattt 2300

 ggctgctcaa gaagatcgag tgaatgtggc agaagtcctc gtaaaccaag 2350

 gggctcatgt ggacgcccag acaaagatgg gatacacacc actgcatgtg 2400

 ggctgccact atggaaatat caagattgtt aatttcctgc tccagcattc 2450

 tgcaaaagtt aatgccaaaa caaagaatgg gtatacgcca ttacatcaag 2500

 cagcacagca ggggcatacg catataataa atgtcttact tcagaacaac 2550

 gcctccccca atgaactcac tgtgaatggg aatactgccc ttggcattgc 2600

 ccggcgcctc ggctacatct cagtagtgga caccctgaag atagtgaccg 2650

 aagaaaccat gaccacaact actgtcacag agaagcacaa aatgaatgtt 2700

 ccagaaacga tgaatgaagt tcttgatatg tctgatgatg aagttcgtaa 2750

 agccaatgcc cctgaaatgc tcagtgatgg cgaatatatc tcagatgttg 2800

 aagaaggtga agatgcaatg accggggaca cagacaaata tcttgggcca 2850

 caggacctta aggaattggg tgatgattcc ctgcctgcag agggttacat 2900

 gggctttagt ctcggagcgc gttctgccag cctccgctcc ttcagttcgg 2950

 ataggtctta caccttgaac agaagctcct atgcacggga cagcatgatg 3000

 attgaagaac tccttgtgcc atccaaagag cagcatctaa cattcacaag 3050

 ggaatttgat tcagattctc ttagacatta cagctgggct gcagacacct 3100

 tagacaatgt caatcttgtt tcaagcccca ttcattctgg gtttctggtt 3150

 agctttatgg tggacgcgag agggggctcc atgagaggaa gccgtcatca 3200

 cgggatgaga atcatcattc ctccacgcaa gtgtacggcc cccactcgaa 3250

 tcacctgccg tttggtaaag agacataaac tggccaaccc acccccacat 3300

 ggtgaaagga gagggattag cagtaggctg gtagaaatgg gtcctgcagg 3350

 ggcacaattt ttaggccctg tcatagtgga aatccctcac tttgggtcca 3400

 tgagaggaaa agagagagaa ctcattgttc ttcgaagtga aaatggtgaa 3450

 acttggaagg agcatcagtt tgacagcaaa aatgaagatt taaccgagtt 3500

 acttaatggc atggatgaag aacttgatag cccagaagag ttagggaaaa 3550

 agcgtatctg caggattatc acgaaagatt tcccccagta ttttgcagtg 3600

 gtttcccgga ttaagcagga aagcaaccag attggtcctg aaggtggaat 3650

 tctgagcagc accacagtgc cccttgttca agcatctttc ccagagggtg 3700

 ccctaactaa aagaattcga gtgggcctcc aggcccagcc tgttccagat 3750

 gaaattgtga aaaagatcct tggaaacaaa gcaactttta gcccaattgt 3800

 cactgtggaa ccaagaagac ggaaattcca taaaccaatc acaatgacca 3850

 ttccggtgcc cccgccctca ggagaaggtg tatccaatgg atacaaaggg 3900

 gacactacac ccaatctgcg tcttctctgt agcattacag ggggcacttc 3950

 gcctgctcag tgggaagaca tcacaggaac aactcctttg acgtttataa 4000

 aagattgtgt ctcctttaca accaatgttt cagccagatt ttggcttgca 4050

 gactgccatc aagttttaga aactgtgggg ttagccacgc aactgtacag 4100

 agaattgata tgtgttccat atatggccaa gtttgttgtt tttgccaaaa 4150

 tgaatgatcc cgtagaatct tccttgcgat gtttctgcat gacagatgac 4200

 aaagtggaca aaactttaga gcaacaagag aattttgagg aagtcgcaag 4250

 aagcaaagat attgaggttc tggaaggaaa acctatttat gttgattgtt 4300

 atggaaattt ggccccactt accaaaggag gacagcaact tgtttttaac 4350

 ttttattctt tcaaagaaaa tagactgcca ttttccatca agattagaga 4400

 caccagccaa gagccctgtg gtcgtctgtc ttttctgaaa gaaccaaaga 4450

 caacaaaagg actgcctcaa acagcggttt gcaacttaaa tatcactctg 4500

 ccagcacata aaaaggagac agagtcagat caagatgatg agattgagaa 4550

 aacagataga cgacagagct tcgcatcctt agctttacgt aagcgctaca 4600

 gctacttgac tgagcctgga atgattgaac ggagtacagg agcaacaaga 4650

 tccctcccca ccacttactc atacaagcca ttcttttcta caagaccata 4700

 ccagtcctgg acaacagctc cgattacagt gcctgggcca gccaagtcag 4750

 gcttcacttc cttatcaagt tcttcctcta atacgccatc agcttctccg 4800

 ttaaaatcaa tatggtctgt ttcgacacct tctccaatca aatccacatt 4850

 aggcgcgtca actacatctt cagttaaatc cattagtgac gtggcatctc 4900

 caattagatc cttacggaca atgtcttcgc cgataaaaac tgtggtgtca 4950

 caatctccat acaatatcca ggtttcctct ggtaccctgg ctagagctcc 5000

 agcagtcacg gaagctacgc ccttaaaagg gctggcatcc aattctacgt 5050

 tttcctctcg aacctctcca gtgactacag cagggtctct tttggagagg 5100

 tcatcaatta ctatgacacc ccctgcctcc cccaaatcaa acattaatat 5150

 gtattcctca agtttgccat ttaagtcaat tattacatca gcagcaccgc 5200

 taatatcttc acctttaaag tcagtggtgt ctccagttaa atcacgagtt 5250

 gatgtcattt catcagccaa aattacaatg gcatcttctc tctcatcacc 5300

 tgtgaagcag atgcctggac atgcagaggt agcattagtc aatggatcta 5350

 tttcccctct aaaatatgca tcatcctcaa ctttaattaa tggatgcaaa 5400

 gccactgcca cgttacagga aaaaatttct tctgctacaa actctgtgag 5450

 ctctgtggtc agtgcagcca ctgacacagt tgagaaagtg ttttctacca 5500

 cgactgcaat gccattttcc ccactcaggt catatgtttc tgcagcacca 5550

 tcagcttttc agtctctaag aactccttcc gcaagtgcac tctatacatc 5600

 ccttgggtcg tcaatatctg caactacctc atctgtaact tcatcaatta 5650

 taacagtgcc agtatactct gtagtcaatg ttttgccaga accagcatta 5700

 aagaaacttc cagactctaa ttcatttaca aaatcagcag cagccttgct 5750

 gtcacccatt aaaacattga ctacggagac acatcctcag cctcacttca 5800

 gtcgaacttc atctccagtt aagtcatctt tgttccttgc accctctgcc 5850

 cttaagttgt ctacaccatc ttctttatct tccagtcagg agatactaaa 5900

 agatgtagct gaaatgaaag aggacctaat gcggatgacc gcaatactac 5950

 agacagatgt gcctgaggag aagccattcc aacctgaact cccaaaggaa 6000

 gggagaatag atgatgaaga acctttcaaa attgtagaga aagtaaagga 6050

 agacttagtg aaagttagtg aaatccttaa aaaggatgta tgtgtagata 6100

 ataaaggatc acccaaatca ccaaagagtg acaaaggaca ctctcctgaa 6150

 gatgactgga tagaatttag ttcggaagaa atccgggaag ccagacaaca 6200

 agctgctgcg agccagtctc catctctgcc agagagagtg caagtaaaag 6250

 caaaagccgc ctccgaaaag gattataact tgaccaaagt tattgattac 6300

 ctaacaaatg atattgggag tagttcactg acaaacttaa aatacaagtt 6350

 tgaggatgca aagaaggatg gtgagggagg acagaaaaga gttttaaaac 6400

 cagcaattgc tttgcaggaa cacaaactca aaatgcctcc agcctccatg 6450

 aggacttcca cctctgagaa agaattgtgt aaaatggctg attccttttt 6500

 tggaacagat actattttag agtctcctga tgacttttct caacacgacc 6550

 aagataaaag tcccttgtct gacagtggct ttgaaacaag aagtgaaaag 6600

 acaccttcag ccccacaaag cgctgaaacg actggtccta aaccactttt 6650

 tcatgaagtt cccatccctc ctgttattac agaaacaaga actgaagtgg 6700

 ttcatgttat caggagctat gatccctcag ctggggatgt tccccagacc 6750

 caaccagagg agcctgtgtc acctaaacct tcacctactt ttatggaatt 6800

 ggaaccaaag cccaccacct ctagtattaa agaaaaggtt aaagcatttc 6850

 aaatgaaagc cagtagtgaa gaagatgacc acaatcgggt tttaagcaaa 6900

 ggcatgcgtg ttaaagaaga gactcacata accacaacca ccagaatggt 6950

 ttatcattct ccaccaggcg gtgaaggtgc atctgaaaga attgaagaaa 7000

 ccatgtcagt ccatgacatc atgaaggcct ttcagtccgg gcgggatcct 7050

 tccaaagaac tggcaggtct gtttgaacat aagtcggcag tgtctccaga 7100

 tgttcacaag tctgctgctg aaacctcagc ccagcatgca gagaaggaca 7150

 accaaatgaa acccaaactg gagcgtataa tagaagtcca catcgaaaaa 7200

 ggtaaccaag ctgagcccac tgaagtcatt attagagaaa ccaaaaagca 7250

 tccagaaaaa gaaatgtatg tatatcagaa agacttatcc cggggagata 7300

 ttaacctaaa agattttctg ccagaaaaac acgatgcttt tccttgttca 7350

 gaggaacagg gtcagcaaga agaagaagaa cttactgctg aagagtcatt 7400

 gccttcttat ctggagtctt ccagagtaaa cactcctgtg tcccaagaag 7450

 aagatagccg ccctagttct gctcaactca tatctgatga ctcttataaa 7500

 acattgaagc ttttgagtca acactcaata gaataccatg acgatgagtt 7550

 gtcagaacta agaggggagt cttacaggtt tgctgagaaa atgcttctgt 7600

 cagaaaagct agatgtgtct cattctgata ctgaggaatc ggttacagac 7650

 catgcaggac cccctagctc agagttacag gggtctgata agcggtccag 7700

 agaaaaaata gccactgccc ccaaaaaaga aattctctcc aaaatctata 7750

 aagatgtttc tgaaaatggt gtaggtaaag tgtctaaaga tgagcatttt 7800

 gataaagtga cagtgttgca ctattctggc aatgttagta gtccaaaaca 7850

 tgccatgtgg atgcgcttta ctgaggacag attagacaga ggtagagaga 7900

 agttgatata tgaagatagg gtggacagga ctgtgaagga ggctgaagaa 7950

 aaactgactg aagtgtcaca gttttttcgt gacaaaactg aaaagctaaa 8000

 tgatgaactg cagtccccag agaaaaaggc acgccctaaa aatggcaaag 8050

 aatattcttc tcaaagccct accagtagca gccctgagaa agtgctactg 8100

 acagaactgc tggcatccaa tgatgagtgg gttaaggcaa gacagcatgg 8150

 ccctgatgga caaggcttcc ccaaggccga ggagaaggca cccagtctgc 8200

 ccagcagccc agagaagatg gttctctccc aacagactga ggacagcaag 8250

 tccacagtgg aagccaaagg aagtatttca cagagcaaag caccagatgg 8300

 gccccagtct ggattccagc tcaaacaatc taaactcagt tccattagat 8350

 taaaatttga acaaggcaca cacgcaaaaa gtaaggacat gtctcaagaa 8400

 gacagaaagt cagatggcca gtccagaatc ccagttaaaa aaatacagga 8450

 gagcaagcta cccgtctacc aagtttttgc tagagaaaaa cagcagaagg 8500

 ccatagacct cccagatgaa agtgtatctg tgcaaaaaga ttttatggta 8550

 ttaaaaacca aagatgagca tgcccaaagc aacgaaattg ttgtaaatga 8600

 ttctggctct gataatgtga aaaaacagag aactgaaatg tcaagtaaag 8650

 caatgcctga ctctttttct gagcagcagg ctaaagactt ggcatgtcat 8700

 ataacctcag atttagcaac taggggacca tgggacaaaa aggtctttag 8750

 aacatgggag agttcgggag ccactaacaa taagtctcag aaagaaaaac 8800

 tttcgcatgt acttgttcat gatgtaagag agaatcacat tggtcaccct 8850

 gagagtaaaa gtgttgatca aaagaatgaa tttatgtctg tgactgagag 8900

 agaacgcaaa ttgttaacaa acggctctct ctcagaaatt aaagaaatga 8950

 ctgtaaaatc tccctccaaa aaagtcttat atagggaata tgttgtgaaa 9000

 gaaggggacc atccaggcgg attgcttgat cagccttcca ggaggagcga 9050

 gagctcagca gtgtcacaca ttcccgtcag agttgctgat gagaggagaa 9100

 tgctgtcttc taatattccc gatggttttt gtgaacagtc ggcatttcca 9150

 aaacatgaac tatcacaaaa attgtcccag tcaagcatga gtaaagagac 9200

 agttgagaca cagcacttta attctataga agatgaaaaa gttacctatt 9250

 cagaaatcag caaagtttcc aaacaccaga gttatgtagg tttatgccca 9300

 cctctcgagg aaaccgaaac ctcccccacc aaatctcctg attctttaga 9350

 gtttagccca ggaaaggaat ctccctctag tgatgtattc gaccacagtc 9400

 ccattgatgg attggaaaaa ctcgcaccac tagcccagac agagggaggg 9450

 aaagagataa aaactttacc cgtttatgtc agttttgtac aagtggggaa 9500

 gcaatatgaa aaggagatac aacaaggagg tgtaaaaaaa atcataagtc 9550

 aggaatgtaa gacagtacaa gaaaccaggg ggacctttta tacaactaga 9600

 cagcaaaagc aacctccttc tccccaaggt agtccagaag atgatactct 9650

 agagcaagta tcctttctag acagctctgg gaaaagccct ttaaccccag 9700

 aaacacccag ttcagaggaa gtgagttatg aatttacatc taagacacct 9750

 gactcgctca tagcttatat accaggcaaa cccagcccaa ttcccgaggt 9800

 ttctgaggag tcagaggagg aggaacaggc caagtcaacc tcccttaagc 9850

 agactacagt ggaggaaaca gcagttgagc gtgaaatgcc taatgacgtg 9900

 agcaaagact ctaaccaaag acccaaaaat aacagagttg cctatattga 9950

 atttccccct cctccaccac tggatgcgga ccagattgag tcagataaga 10000

 agcatcatta tctcccagaa aaagaggttg acatgattga agtcaatctg 10050

 caagatgagc atgacaagta ccagctggct gaacctgtca ttagagtgca 10100

 gccaccttca ccagttcctc ccggggcaga cgtcagtgat tcaagcgatg 10150

 acgaatctat ttatcagcca gtcccagtta aaaaatatac cttcaaatta 10200

 aaggaagtgg acgatgaaca aaaagaaaaa cccaaagctt ctgctgaaaa 10250

 ggcttccaac cagaaagaac tggaaagtaa tggatctgga aaagataatg 10300

 aatttggcct tggccttgat tcacctcaga atgaaattgc ccagaatggg 10350

 aacaacgacc agtccatcac agagtgttcc attgccacca cagcagagtt 10400

 ttctcatgac acggatgcca cagagatcga ctctctggat ggctatgacc 10450

 tgcaagatga agatgatggc ttgacagaga gtgattctaa actcccaatt 10500

 caagccatgg aaattaagaa agatatctgg aacacagagg gcattctgaa 10550

 gccagctgac cgctctttta gccaaagtaa acttgaagtt atcgaggagg 10600

 agggaaaggt gggaccagat gaggacaagc caccttctaa aagttcttca 10650

 tctgaaaaga ctcctgataa gactgatcag aagtcagggg cccagttctt 10700

 cacactggaa ggcagacatc ctgacagatc agtgtttcct gatacttact 10750

 tcagttacaa agtagatgaa gaatttgcca ctccttttaa aacagtagct 10800

 accaaaggtc tagattttga cccttggtct aataaccgag gggatgatga 10850

 agtttttgac agtaaatcac gggaagatga aactaagcca tttgggctgg 10900

 cggtagaaga ccgctctcca gcaacaaccc ctgatacaac gccagccaga 10950

 acgccaactg atgaaagtac cccaactagt gagcctaacc ccttcccatt 11000

 tcatgaagga aaaatgtttg agatgactcg cagtggtgca attgacatga 11050

 gcaagaggga ttttgttgaa gagaggctcc aatttttcca gattggtgag 11100

 catacttctg aagggaagtc aggggaccag ggggaagggg ataaaagtat 11150

 ggtcactgcc acaccacagc cacagtcagg ggacaccact gtagaaacca 11200

 atctagagag aaatgtagag acacctacag tggaacctaa ccccagcatc 11250

 ccgaccagcg gagagtgtca ggaaggcaca tccagtagtg gctccctgga 11300

 gaaatcagca gcagccacta acacctctaa agttgacccc aagttgcgca 11350

 cgcctataaa aatgggaatt tctgcatcca ccatgaccat gaagaaagaa 11400

 ggccctggag aaataacaga taagatagaa gcggtgatga ccagttgtca 11450

 gggattagaa aatgaaacta taacaatgat ttcaaataca gccaatagcc 11500

 agatgggcgt taggccccat gaaaaacatg attttcaaaa agataacttt 11550

 aataacaaca acaatttgga ttcttccact atacagacag ataacattat 11600

 gagtaatata gttctgacag aacattctgc acccacttgt accacagaga 11650

 aagataaccc agtgaaagtc tcatcaggaa aaaagacagg ggtactacaa 11700

 ggacactgtg taagagataa gcagaaagtt cttggagaac agcaaaaaac 11750

 aaaggaattg atagggatta ggcaaaaatc caaacttccc ataaaggcca 11800

 cttcaccaaa agataccttc ccaccgaacc atatgtcaaa cactaaagca 11850

 agtaaaatga agcaggttag tcaatccgag aaaaccaaag cccttactac 11900

 ttcttcatgt gtagatgtaa agtccagaat tccagtgaaa aacacaccca 11950

 gggataacat aattgcagtt agaaaagcat gtgccacaca aaagcaaggg 12000

 cagccagaga aaggcaaggc caaacagctt ccatccaagt tgccagtaaa 12050

 ggtaagatcc acctgtgtca ctaccaccac caccactgcc accaccacca 12100

 ccactaccac cactaccacc accaccagct gcacagttaa agttaggaaa 12150

 agtcagctca aggaagtatg taaacattcc attgaatatt ttaagggaat 12200

 tagtggtgag accttaaagc ttgtggaccg cctctctgaa gaagaaaaaa 12250

 agatgcagtc cgagttgtcc gatgaggaag aaagtacctc aagaaacacg 12300

 tcgttgtccg agacttcccg gggtggccag ccttcggtta caacgaagtc 12350

 tgctagagat aagaaaacag aggcagcacc tttaaaatca aagagtgaaa 12400

 aggccggcag tgagaaaagg agcagtagaa ggactggtcc acagagtcca 12450

 tgtgaacgga cagatatcag gatggcaata gtagccgatc acctgggact 12500

 tagttggaca gaactggcaa gggaactgaa tttttcagtg gatgaaatca 12550

 atcaaatacg tgtggaaaat ccaaattctt taatttctca gagcttcatg 12600

 ttattaaaaa aatgggttac cagagacgga aaaaatgcca caactgatgc 12650

 cttaacttcg gtcttgacaa aaattaatcg aatagatata gtgacactgc 12700

 tagaaggacc aatatttgat tatggaaata tttcaggcac cagaagtttt 12750

 gcagatgaga acaatgtttt ccatgaccct gttgatggtt ggcagaatga 12800

 gacatcaagt ggaaacctag agtcctgcgc tcaagctcga agagtaactg 12850

 gtgggttact agatcgactg gatgacagcc ctgaccagtg tagagattcc 12900

 attacctcat atctcaaagg agaagctggc aaatttgaag caaatggaag 12950

 ccatacagaa atcactccag aagcaaagac aaaatcttac tttccagaat 13000

 cccaaaatga tgtaggaaaa cagagtacca aggaaactct gaaaccaaaa 13050

 atacatggat ctggtcatgt tgaagaacca gcatcaccac tagcagcata 13100

 tcagaaatct ctagaagaaa ccagcaagct tataatagaa gagactaaac 13150

 cctgtgtgcc tgtcagtatg aaaaagatga gtaggacttc tccagcagat 13200

 ggcaagccaa ggcttagcct ccatgaagaa gaggggtcca gtgggtctga 13250

 gcaaaagcag ggagaaggtt ttaaggtgaa aacgaagaaa gaaatccggc 13300

 atgtggaaaa gaagagccac tcgtaacagc gaacggtcag tcaaggatca 13350

 taagttttta ctgccagtat tgagaaattc gtggaagaaa tgtcagcagg 13400

 aagtaaaaat tcaccgagaa gtgtgtgtgt gttcgctgct tccacacatt 13450

 aatggcatga ttttttttat gcaaaaagaa aagaaaagaa aaccacccac 13500

 attttaattt agcatgagcc aatttacaga gcatggaaat cactttcatt 13550

 tccggattgg cgcgtgtgca attagcaatg cagtgtatat acaagaagcc 13600

 atgctgttaa cagtttatct caagtaattt ggtgtcattt acaaaaggaa 13650

 gaaattcttg ccatcagaag ggacagaagg agatggaatg atcaaatcac 13700

 agagaaacac taaaattact aaatctacaa cagctcgcct tatttttctt 13750

 ggacccaaac tgtcagggta taaacactat ttgtttcttt tttaaaacat 13800

 cgatagtttt gctgtaaata ataacactgt ataaattcta acagaaaaat 13850

 agaataaaat gttgataagg cactgcctct tagaacacaa acagaatatt 13900

 gcaaatgcat ttaacaaata ggggtctcaa gtgacttcac cctagaagag 13950

 gagggaggga ttctgggtgg gggtgactct tcactgattc ttgtatatta 14000

 gcaattataa tgtttgtata tgcaaaactg ctagcttgat tttaaaaaaa 14050

 aacaaatctt taaaatctgc tgcaaattta aataattccc aaaatgagga 14100

 attctgtagt tctgtgaaaa atttttttct tcagaatact aatattttga 14150

 tgcatgtgta tcaccttatt ttgattaaat cttttccaat tttgcaaaca 14200

 ctacagtata ctgcaacaca aaagatttta tctgtaaaca caaagccctt 14250

 catctaatat ttgttgctat tgccaatttt tcaatgaaat gacctaaaaa 14300

 caacaaaaaa aaataaccta tacggtagtt gctttagggg gtggggggat 14350

 gctatctgtt agtgcttaaa agggggtaaa tgcttgccgc tttagaggtg 14400

 gatggtgctc ataaaaggcc ccagtcgggg gtatttaaaa aggactgaac 14450

 agaaatcctt agctagtaga atggcagcac gctgtaaaat tattactgta 14500

 ttgtgtactg gctataagat gtagacacct ttcagtaagc caatcatttg 14550

 taaccattct agcagtgtca tattaggtta ataaggctgc tgtgttttaa 14600

 agggcatttt tatttgggtt ttggtgaaat tctttaattt gttgattata 14650

 ttcacataaa atcagcattc attgacacat agctctaatg acatatgtat 14700

 gaaaaaccat acactggatg acctagtcga ttatttaagc ataaaataaa 14750

 ttgtgttaaa ctcttcacct 14770

<210> 1510
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1510
 Met Ala His Ala Ala Ser Gln Leu Lys Lys Asn Arg Asp Leu Glu
   1               5                  10                  15

 Ile Asn Ala Glu Glu Glu Pro Glu Lys Lys Arg Lys His Arg Lys
                  20                  25                  30

 Arg Ser Arg Asp Arg Lys Lys Lys Ser Asp Ala Asn Ala Ser Tyr
                  35                  40                  45

 Leu Arg Ala Ala Arg Ala Gly His Leu Glu Lys Ala Leu Asp Tyr
                  50                  55                  60

 Ile Lys Asn Gly Val Asp Ile Asn Ile Cys Asn Gln Asn Gly Leu
                  65                  70                  75

 Asn Ala Leu His Leu Ala Ser Lys Glu Gly His Val Glu Val Val
                  80                  85                  90

 Ser Glu Leu Leu Gln Arg Glu Ala Asn Val Asp Ala Ala Thr Lys
                  95                 100                 105

 Lys Gly Asn Thr Ala Leu His Ile Ala Ser Leu Ala Gly Gln Ala
                 110                 115                 120

 Glu Val Val Lys Val Leu Val Thr Asn Gly Ala Asn Val Asn Ala
                 125                 130                 135

 Gln Ser Gln Asn Gly Phe Thr Pro Leu Tyr Met Ala Ala Gln Glu
                 140                 145                 150

 Asn His Leu Glu Val Val Lys Phe Leu Leu Asp Asn Gly Ala Ser
                 155                 160                 165

 Gln Ser Leu Ala Thr Glu Asp Gly Phe Thr Pro Leu Ala Val Ala
                 170                 175                 180

 Leu Gln Gln Gly His Asp Gln Val Val Ser Leu Leu Leu Glu Asn
                 185                 190                 195

 Asp Thr Lys Gly Lys Val Arg Leu Pro Ala Leu His Ile Ala Ala
                 200                 205                 210

 Arg Lys Asp Asp Thr Lys Ala Ala Ala Leu Leu Leu Gln Asn Asp
                 215                 220                 225

 Asn Asn Ala Asp Val Glu Ser Lys Ser Gly Phe Thr Pro Leu His
                 230                 235                 240

 Ile Ala Ala His Tyr Gly Asn Ile Asn Val Ala Thr Leu Leu Leu
                 245                 250                 255

 Asn Arg Ala Ala Ala Val Asp Phe Thr Ala Arg Asn Asp Ile Thr
                 260                 265                 270

 Pro Leu His Val Ala Ser Lys Arg Gly Asn Ala Asn Met Val Lys
                 275                 280                 285

 Leu Leu Leu Asp Arg Gly Ala Lys Ile Asp Ala Lys Thr Arg Asp
                 290                 295                 300

 Gly Leu Thr Pro Leu His Cys Gly Ala Arg Ser Gly His Glu Gln
                 305                 310                 315

 Val Val Glu Met Leu Leu Asp Arg Ala Ala Pro Ile Leu Ser Lys
                 320                 325                 330

 Thr Lys Asn Gly Leu Ser Pro Leu His Met Ala Thr Gln Gly Asp
                 335                 340                 345

 His Leu Asn Cys Val Gln Leu Leu Leu Gln His Asn Val Pro Val
                 350                 355                 360

 Asp Asp Val Thr Asn Asp Tyr Leu Thr Ala Leu His Val Ala Ala
                 365                 370                 375

 His Cys Gly His Tyr Lys Val Ala Lys Val Leu Leu Asp Lys Lys
                 380                 385                 390

 Ala Asn Pro Asn Ala Lys Ala Leu Asn Gly Phe Thr Pro Leu His
                 395                 400                 405

 Ile Ala Cys Lys Lys Asn Arg Ile Lys Val Met Glu Leu Leu Leu
                 410                 415                 420

 Lys His Gly Ala Ser Ile Gln Ala Val Thr Glu Ser Gly Leu Thr
                 425                 430                 435

 Pro Ile His Val Ala Ala Phe Met Gly His Val Asn Ile Val Ser
                 440                 445                 450

 Gln Leu Met His His Gly Ala Ser Pro Asn Thr Thr Asn Val Arg
                 455                 460                 465

 Gly Glu Thr Ala Leu His Met Ala Ala Arg Ser Gly Gln Ala Glu
                 470                 475                 480

 Val Val Arg Tyr Leu Val Gln Asp Gly Ala Gln Val Glu Ala Lys
                 485                 490                 495

 Ala Lys Asp Asp Gln Thr Pro Leu His Ile Ser Ala Arg Leu Gly
                 500                 505                 510

 Lys Ala Asp Ile Val Gln Gln Leu Leu Gln Gln Gly Ala Ser Pro
                 515                 520                 525

 Asn Ala Ala Thr Thr Ser Gly Tyr Thr Pro Leu His Leu Ser Ala
                 530                 535                 540

 Arg Glu Gly His Glu Asp Val Ala Ala Phe Leu Leu Asp His Gly
                 545                 550                 555

 Ala Ser Leu Ser Ile Thr Thr Lys Lys Gly Phe Thr Pro Leu His
                 560                 565                 570

 Val Ala Ala Lys Tyr Gly Lys Leu Glu Val Ala Asn Leu Leu Leu
                 575                 580                 585

 Gln Lys Ser Ala Ser Pro Asp Ala Ala Gly Lys Ser Gly Leu Thr
                 590                 595                 600

 Pro Leu His Val Ala Ala His Tyr Asp Asn Gln Lys Val Ala Leu
                 605                 610                 615

 Leu Leu Leu Asp Gln Gly Ala Ser Pro His Ala Ala Ala Lys Asn
                 620                 625                 630

 Gly Tyr Thr Pro Leu His Ile Ala Ala Lys Lys Asn Gln Met Asp
                 635                 640                 645

 Ile Ala Thr Thr Leu Leu Glu Tyr Gly Ala Asp Ala Asn Ala Val
                 650                 655                 660

 Thr Arg Gln Gly Ile Ala Ser Val His Leu Ala Ala Gln Glu Gly
                 665                 670                 675

 His Val Asp Met Val Ser Leu Leu Leu Gly Arg Asn Ala Asn Val
                 680                 685                 690

 Asn Leu Ser Asn Lys Ser Gly Leu Thr Pro Leu His Leu Ala Ala
                 695                 700                 705

 Gln Glu Asp Arg Val Asn Val Ala Glu Val Leu Val Asn Gln Gly
                 710                 715                 720

 Ala His Val Asp Ala Gln Thr Lys Met Gly Tyr Thr Pro Leu His
                 725                 730                 735

 Val Gly Cys His Tyr Gly Asn Ile Lys Ile Val Asn Phe Leu Leu
                 740                 745                 750

 Gln His Ser Ala Lys Val Asn Ala Lys Thr Lys Asn Gly Tyr Thr
                 755                 760                 765

 Pro Leu His Gln Ala Ala Gln Gln Gly His Thr His Ile Ile Asn
                 770                 775                 780

 Val Leu Leu Gln Asn Asn Ala Ser Pro Asn Glu Leu Thr Val Asn
                 785                 790                 795

 Gly Asn Thr Ala Leu Gly Ile Ala Arg Arg Leu Gly Tyr Ile Ser
                 800                 805                 810

 Val Val Asp Thr Leu Lys Ile Val Thr Glu Glu Thr Met Thr Thr
                 815                 820                 825

 Thr Thr Val Thr Glu Lys His Lys Met Asn Val Pro Glu Thr Met
                 830                 835                 840

 Asn Glu Val Leu Asp Met Ser Asp Asp Glu Val Arg Lys Ala Asn
                 845                 850                 855

 Ala Pro Glu Met Leu Ser Asp Gly Glu Tyr Ile Ser Asp Val Glu
                 860                 865                 870

 Glu Gly Glu Asp Ala Met Thr Gly Asp Thr Asp Lys Tyr Leu Gly
                 875                 880                 885

 Pro Gln Asp Leu Lys Glu Leu Gly Asp Asp Ser Leu Pro Ala Glu
                 890                 895                 900

 Gly Tyr Met Gly Phe Ser Leu Gly Ala Arg Ser Ala Ser Leu Arg
                 905                 910                 915

 Ser Phe Ser Ser Asp Arg Ser Tyr Thr Leu Asn Arg Ser Ser Tyr
                 920                 925                 930

 Ala Arg Asp Ser Met Met Ile Glu Glu Leu Leu Val Pro Ser Lys
                 935                 940                 945

 Glu Gln His Leu Thr Phe Thr Arg Glu Phe Asp Ser Asp Ser Leu
                 950                 955                 960

 Arg His Tyr Ser Trp Ala Ala Asp Thr Leu Asp Asn Val Asn Leu
                 965                 970                 975

 Val Ser Ser Pro Ile His Ser Gly Phe Leu Val Ser Phe Met Val
                 980                 985                 990

 Asp Ala Arg Gly Gly Ser Met Arg Gly Ser Arg His His Gly Met
                 995                1000                1005

 Arg Ile Ile Ile Pro Pro Arg Lys Cys Thr Ala Pro Thr Arg Ile
                1010                1015                1020

 Thr Cys Arg Leu Val Lys Arg His Lys Leu Ala Asn Pro Pro Pro
                1025                1030                1035

 His Gly Glu Arg Arg Gly Ile Ser Ser Arg Leu Val Glu Met Gly
                1040                1045                1050

 Pro Ala Gly Ala Gln Phe Leu Gly Pro Val Ile Val Glu Ile Pro
                1055                1060                1065

 His Phe Gly Ser Met Arg Gly Lys Glu Arg Glu Leu Ile Val Leu
                1070                1075                1080

 Arg Ser Glu Asn Gly Glu Thr Trp Lys Glu His Gln Phe Asp Ser
                1085                1090                1095

 Lys Asn Glu Asp Leu Thr Glu Leu Leu Asn Gly Met Asp Glu Glu
                1100                1105                1110

 Leu Asp Ser Pro Glu Glu Leu Gly Lys Lys Arg Ile Cys Arg Ile
                1115                1120                1125

 Ile Thr Lys Asp Phe Pro Gln Tyr Phe Ala Val Val Ser Arg Ile
                1130                1135                1140

 Lys Gln Glu Ser Asn Gln Ile Gly Pro Glu Gly Gly Ile Leu Ser
                1145                1150                1155

 Ser Thr Thr Val Pro Leu Val Gln Ala Ser Phe Pro Glu Gly Ala
                1160                1165                1170

 Leu Thr Lys Arg Ile Arg Val Gly Leu Gln Ala Gln Pro Val Pro
                1175                1180                1185

 Asp Glu Ile Val Lys Lys Ile Leu Gly Asn Lys Ala Thr Phe Ser
                1190                1195                1200

 Pro Ile Val Thr Val Glu Pro Arg Arg Arg Lys Phe His Lys Pro
                1205                1210                1215

 Ile Thr Met Thr Ile Pro Val Pro Pro Pro Ser Gly Glu Gly Val
                1220                1225                1230

 Ser Asn Gly Tyr Lys Gly Asp Thr Thr Pro Asn Leu Arg Leu Leu
                1235                1240                1245

 Cys Ser Ile Thr Gly Gly Thr Ser Pro Ala Gln Trp Glu Asp Ile
                1250                1255                1260

 Thr Gly Thr Thr Pro Leu Thr Phe Ile Lys Asp Cys Val Ser Phe
                1265                1270                1275

 Thr Thr Asn Val Ser Ala Arg Phe Trp Leu Ala Asp Cys His Gln
                1280                1285                1290

 Val Leu Glu Thr Val Gly Leu Ala Thr Gln Leu Tyr Arg Glu Leu
                1295                1300                1305

 Ile Cys Val Pro Tyr Met Ala Lys Phe Val Val Phe Ala Lys Met
                1310                1315                1320

 Asn Asp Pro Val Glu Ser Ser Leu Arg Cys Phe Cys Met Thr Asp
                1325                1330                1335

 Asp Lys Val Asp Lys Thr Leu Glu Gln Gln Glu Asn Phe Glu Glu
                1340                1345                1350

 Val Ala Arg Ser Lys Asp Ile Glu Val Leu Glu Gly Lys Pro Ile
                1355                1360                1365

 Tyr Val Asp Cys Tyr Gly Asn Leu Ala Pro Leu Thr Lys Gly Gly
                1370                1375                1380

 Gln Gln Leu Val Phe Asn Phe Tyr Ser Phe Lys Glu Asn Arg Leu
                1385                1390                1395

 Pro Phe Ser Ile Lys Ile Arg Asp Thr Ser Gln Glu Pro Cys Gly
                1400                1405                1410

 Arg Leu Ser Phe Leu Lys Glu Pro Lys Thr Thr Lys Gly Leu Pro
                1415                1420                1425

 Gln Thr Ala Val Cys Asn Leu Asn Ile Thr Leu Pro Ala His Lys
                1430                1435                1440

 Lys Glu Thr Glu Ser Asp Gln Asp Asp Glu Ile Glu Lys Thr Asp
                1445                1450                1455

 Arg Arg Gln Ser Phe Ala Ser Leu Ala Leu Arg Lys Arg Tyr Ser
                1460                1465                1470

 Tyr Leu Thr Glu Pro Gly Met Ile Glu Arg Ser Thr Gly Ala Thr
                1475                1480                1485

 Arg Ser Leu Pro Thr Thr Tyr Ser Tyr Lys Pro Phe Phe Ser Thr
                1490                1495                1500

 Arg Pro Tyr Gln Ser Trp Thr Thr Ala Pro Ile Thr Val Pro Gly
                1505                1510                1515

 Pro Ala Lys Ser Gly Phe Thr Ser Leu Ser Ser Ser Ser Ser Asn
                1520                1525                1530

 Thr Pro Ser Ala Ser Pro Leu Lys Ser Ile Trp Ser Val Ser Thr
                1535                1540                1545

 Pro Ser Pro Ile Lys Ser Thr Leu Gly Ala Ser Thr Thr Ser Ser
                1550                1555                1560

 Val Lys Ser Ile Ser Asp Val Ala Ser Pro Ile Arg Ser Leu Arg
                1565                1570                1575

 Thr Met Ser Ser Pro Ile Lys Thr Val Val Ser Gln Ser Pro Tyr
                1580                1585                1590

 Asn Ile Gln Val Ser Ser Gly Thr Leu Ala Arg Ala Pro Ala Val
                1595                1600                1605

 Thr Glu Ala Thr Pro Leu Lys Gly Leu Ala Ser Asn Ser Thr Phe
                1610                1615                1620

 Ser Ser Arg Thr Ser Pro Val Thr Thr Ala Gly Ser Leu Leu Glu
                1625                1630                1635

 Arg Ser Ser Ile Thr Met Thr Pro Pro Ala Ser Pro Lys Ser Asn
                1640                1645                1650

 Ile Asn Met Tyr Ser Ser Ser Leu Pro Phe Lys Ser Ile Ile Thr
                1655                1660                1665

 Ser Ala Ala Pro Leu Ile Ser Ser Pro Leu Lys Ser Val Val Ser
                1670                1675                1680

 Pro Val Lys Ser Arg Val Asp Val Ile Ser Ser Ala Lys Ile Thr
                1685                1690                1695

 Met Ala Ser Ser Leu Ser Ser Pro Val Lys Gln Met Pro Gly His
                1700                1705                1710

 Ala Glu Val Ala Leu Val Asn Gly Ser Ile Ser Pro Leu Lys Tyr
                1715                1720                1725

 Ala Ser Ser Ser Thr Leu Ile Asn Gly Cys Lys Ala Thr Ala Thr
                1730                1735                1740

 Leu Gln Glu Lys Ile Ser Ser Ala Thr Asn Ser Val Ser Ser Val
                1745                1750                1755

 Val Ser Ala Ala Thr Asp Thr Val Glu Lys Val Phe Ser Thr Thr
                1760                1765                1770

 Thr Ala Met Pro Phe Ser Pro Leu Arg Ser Tyr Val Ser Ala Ala
                1775                1780                1785

 Pro Ser Ala Phe Gln Ser Leu Arg Thr Pro Ser Ala Ser Ala Leu
                1790                1795                1800

 Tyr Thr Ser Leu Gly Ser Ser Ile Ser Ala Thr Thr Ser Ser Val
                1805                1810                1815

 Thr Ser Ser Ile Ile Thr Val Pro Val Tyr Ser Val Val Asn Val
                1820                1825                1830

 Leu Pro Glu Pro Ala Leu Lys Lys Leu Pro Asp Ser Asn Ser Phe
                1835                1840                1845

 Thr Lys Ser Ala Ala Ala Leu Leu Ser Pro Ile Lys Thr Leu Thr
                1850                1855                1860

 Thr Glu Thr His Pro Gln Pro His Phe Ser Arg Thr Ser Ser Pro
                1865                1870                1875

 Val Lys Ser Ser Leu Phe Leu Ala Pro Ser Ala Leu Lys Leu Ser
                1880                1885                1890

 Thr Pro Ser Ser Leu Ser Ser Ser Gln Glu Ile Leu Lys Asp Val
                1895                1900                1905

 Ala Glu Met Lys Glu Asp Leu Met Arg Met Thr Ala Ile Leu Gln
                1910                1915                1920

 Thr Asp Val Pro Glu Glu Lys Pro Phe Gln Pro Glu Leu Pro Lys
                1925                1930                1935

 Glu Gly Arg Ile Asp Asp Glu Glu Pro Phe Lys Ile Val Glu Lys
                1940                1945                1950

 Val Lys Glu Asp Leu Val Lys Val Ser Glu Ile Leu Lys Lys Asp
                1955                1960                1965

 Val Cys Val Asp Asn Lys Gly Ser Pro Lys Ser Pro Lys Ser Asp
                1970                1975                1980

 Lys Gly His Ser Pro Glu Asp Asp Trp Ile Glu Phe Ser Ser Glu
                1985                1990                1995

 Glu Ile Arg Glu Ala
                2000

<210> 1511
<211> 1313
<212> DNA
<213> Homo sapien

<400> 1511
 gtgggcagcc gaggccgcga actgcatcat ggagaatttt gtagccacct 50

 tggctaatgg gatgagcctc cagccgcctc ttgaagaagt gtcctgtggc 100

 caggcggaaa gcagtgagaa gcccaacgct gaggacatga catccaaaga 150

 ttactacttt gactcctacg cacactttgg catccacgag gagatgctga 200

 aggacgaggt gcgcaccctc acttaccgca actccatgtt tcataaccgg 250

 cacctcttca aggacaaggt ggtgctggac gtcggctcgg gcaccggcat 300

 cctctgcatg tttgctgcca aggccggggc ccgcaaggtc atcgggatcg 350

 tgtgttccag tatctctgat tatgcggtga agatcgtcaa agccaacaag 400

 ttagaccacg tggtgaccat catcaagggg aaggtggagg aggtggagct 450

 cccagtggag aaggtggcat catcatcagc gagtggatgg gctactgcct 500

 cttctacgag tccatgctca acaccgtgct ctatgcccgg gacaagtgtg 550

 gcgcccgatg gcctcatctt cccagaccgg gccacgctgt atgtgacggc 600

 catcgaggac cggcagtaca aagactacaa gatccactgg tgggagaacg 650

 tgtatggctt cgacatgtct tgcatcaaag atgtggccat taaggagccc 700

 ctagtggatg tcgtggaccc caaacagctg gtcaccaacg cctgcctcat 750

 aaaggaggtg gacatctata ccgtcaaggt ggaagacctg accttcacct 800

 ccccgttctg cctgcaagtg aagcggaatg actacgtgca cgccctggtg 850

 gcctacttca acatcgagtt cacacgctgc cacaagagga ccggcttctc 900

 caccagcccc gagtccccgt acacgcactg gaagcagacg gtgttctaca 950

 tggaggacta cctgaccgtg aagacgggcg aggagatctt cggcaccatc 1000

 ggcatgcggc ccaacgccaa gaacaaccgg gacctggact tcaccatcga 1050

 cctggacttc aagggccagc tgtgcgagct gtcctgctcc accgactacc 1100

 ggatgcgctg aggcccggct ctcccgccct gcacgagccc aggggctgag 1150

 cgttcctagg cggtttcggg gctccccctt cctctccctc cctcccgcag 1200

 aagggggttt taggggcctg ggctgggggg atggggaggg cacatcgtga 1250

 ctgtgttttt cataacttat gtttttatat ggttgcattt acgccaataa 1300

 atcctcagct ggg 1313

<210> 1512
<211> 360
<212> PRT
<213> Homo sapien

<400> 1512
 Met Glu Asn Phe Val Ala Thr Leu Ala Asn Gly Met Ser Leu Gln
   1               5                  10                  15

 Pro Pro Leu Glu Glu Val Ser Cys Gly Gln Ala Glu Ser Ser Glu
                  20                  25                  30

 Lys Pro Asn Ala Glu Asp Met Thr Ser Lys Asp Tyr Tyr Phe Asp
                  35                  40                  45

 Ser Tyr Ala His Phe Gly Ile His Glu Glu Met Leu Lys Asp Glu
                  50                  55                  60

 Val Arg Thr Leu Thr Tyr Arg Asn Ser Met Phe His Asn Arg His
                  65                  70                  75

 Leu Phe Lys Asp Lys Val Val Leu Asp Val Gly Ser Gly Thr Gly
                  80                  85                  90

 Ile Leu Cys Met Phe Ala Ala Lys Ala Gly Ala Arg Lys Val Ile
                  95                 100                 105

 Gly Ile Val Cys Ser Ser Ile Ser Asp Tyr Ala Val Lys Ile Val
                 110                 115                 120

 Lys Ala Asn Lys Leu Asp His Val Val Thr Ile Ile Lys Gly Lys
                 125                 130                 135

 Val Glu Glu Val Glu Leu Pro Val Glu Lys Val Ala Ser Ser Ser
                 140                 145                 150

 Ala Ser Gly Trp Ala Thr Ala Ser Ser Thr Ser Pro Cys Ser Thr
                 155                 160                 165

 Pro Cys Ser Met Pro Gly Thr Ser Val Ala Pro Asp Gly Leu Ile
                 170                 175                 180

 Phe Pro Asp Arg Ala Thr Leu Tyr Val Thr Ala Ile Glu Asp Arg
                 185                 190                 195

 Gln Tyr Lys Asp Tyr Lys Ile His Trp Trp Glu Asn Val Tyr Gly
                 200                 205                 210

 Phe Asp Met Ser Cys Ile Lys Asp Val Ala Ile Lys Glu Pro Leu
                 215                 220                 225

 Val Asp Val Val Asp Pro Lys Gln Leu Val Thr Asn Ala Cys Leu
                 230                 235                 240

 Ile Lys Glu Val Asp Ile Tyr Thr Val Lys Val Glu Asp Leu Thr
                 245                 250                 255

 Phe Thr Ser Pro Phe Cys Leu Gln Val Lys Arg Asn Asp Tyr Val
                 260                 265                 270

 His Ala Leu Val Ala Tyr Phe Asn Ile Glu Phe Thr Arg Cys His
                 275                 280                 285

 Lys Arg Thr Gly Phe Ser Thr Ser Pro Glu Ser Pro Tyr Thr His
                 290                 295                 300

 Trp Lys Gln Thr Val Phe Tyr Met Glu Asp Tyr Leu Thr Val Lys
                 305                 310                 315

 Thr Gly Glu Glu Ile Phe Gly Thr Ile Gly Met Arg Pro Asn Ala
                 320                 325                 330

 Lys Asn Asn Arg Asp Leu Asp Phe Thr Ile Asp Leu Asp Phe Lys
                 335                 340                 345

 Gly Gln Leu Cys Glu Leu Ser Cys Ser Thr Asp Tyr Arg Met Arg
                 350                 355                 360

<210> 1513
<211> 367
<212> DNA
<213> Homo sapien

<400> 1513
 ctccagtctc acctcggctt gcaatggacc ccaactgctc ctgcgaggct 50

 ggtggctcct gcgcctgcgc cggctcctgc aagtgcaaaa agtgcaaatg 100

 cacctcctgc aagaagagct gctgctcctg ttgccccctg ggctgtgcca 150

 agtgtgccca gggctgcatc tgcaaagggg cgtcagagaa gtgcagctgc 200

 tgtgcctgat gtcgggacag ccctgctgtc agatgaaaac agaatgacac 250

 gtaaaatccg aggttttttt tttctacaac tccgactcat ttgctacatt 300

 cctttttttc tgtgaaatat gtgaataata attaaacact tagacttgaa 350

 aaaaaaaaaa aaaaaaa 367

<210> 1514
<211> 61
<212> PRT
<213> Homo sapien

<400> 1514
 Met Asp Pro Asn Cys Ser Cys Glu Ala Gly Gly Ser Cys Ala Cys
   1               5                  10                  15

 Ala Gly Ser Cys Lys Cys Lys Lys Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Leu Gly Cys Ala Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Ile Cys Lys Gly Ala Ser Glu Lys Cys Ser Cys Cys
                  50                  55                  60

 Ala


<210> 1515
<211> 1991
<212> DNA
<213> Homo sapien

<400> 1515
 acaggggtga aggcccagag accagcagaa cggcatccca gccacgacgg 50

 ccactttgct ctgtctgctg tccgccacgg ccctgctctg ttccctggga 100

 cacccccgcc cccacctcct caggctgcct gatctgccca gctttccagc 150

 tttcctctgg attccggcct ctggtcatcc ctccccaccc tctctccaag 200

 gccctctcct ggtctccctt cttctagaac cccttcctcc acctccctct 250

 ctgcagaact tctcctttac cccccacccc ccaccactgc cccctttcct 300

 tttctgacct ccttttggag ggctcagcgc tgcccagacc ataggagaga 350

 tgtgggaggc tcagttcctg ggcttgctgt ttctgcagcc gctttgggtg 400

 gctccagtga agcctctcca gccaggggct gaggtcccgg tggtgtgggc 450

 ccaggagggg gctcctgccc agctcccctg cagccccaca atccccctcc 500

 aggatctcag ccttctgcga agagcagggg tcacttggca gcatcagcca 550

 gacagtggcc cgcccgctgc cgcccccggc catcccctgg cccccggccc 600

 tcacccggcg gcgccctcct cctgggggcc caggccccgc cgctacacgg 650

 tgctgagcgt gggtcccgga ggcctgcgca gcgggaggct gcccctgcag 700

 ccccgcgtcc agctggatga gcgcggccgg cagcgcgggg acttctcgct 750

 atggctgcgc ccagcccggc gcgcggacgc cggcgagtac cgcgccgcgg 800

 tgcacctcag ggaccgcgcc ctctcctgcc gcctccgtct gcgcctgggc 850

 caggcctcga tgactgccag ccccccagga tctctcagag cctccgactg 900

 ggtcattttg aactgctcct tcagccgccc tgaccgccca gcctctgtgc 950

 attggttccg gaaccggggc cagggccgag tccctgtccg ggagtccccc 1000

 catcaccact tagcggaaag cttcctcttc ctgccccaag tcagccccat 1050

 ggactctggg ccctggggct gcatcctcac ctacagagat ggcttcaacg 1100

 tctccatcat gtataacctc actgttctgg gtctggagcc cccaactccc 1150

 ttgacagtgt acgctggagc aggttccagg gtggggctgc cctgccgcct 1200

 gcctgctggt gtggggaccc ggtctttcct cactgccaag tggactcctc 1250

 ctgggggagg ccctgacctc ctggtgactg gagacaatgg cgactttacc 1300

 cttcgactag aggatgtgag ccaggcccag gctgggacct acacctgcca 1350

 tatccatctg caggaacagc agctcaatgc cactgtcaca ttggcaatca 1400

 tcacagtgac tcccaaatcc tttgggtcac ctggatccct ggggaagctg 1450

 ctttgtgagg tgactccagt atctggacaa gaacgctttg tgtggagctc 1500

 tctggacacc ccatcccaga ggagtttctc aggaccttgg ctggaggcac 1550

 aggaggccca gctcctttcc cagccttggc aatgccagct gtaccagggg 1600

 gagaggcttc ttggagcagc agtgtacttc acagagctgt ctagcccagg 1650

 tgcccaacgc tctgggagag ccccaggtgc cctcccagca ggccacctcc 1700

 tgctgtttct cacccttggt gtcctttctc tgctcctttt ggtgactgga 1750

 gcctttggct ttcacctttg gagaagacag tggcgaccaa gacgattttc 1800

 tgccttagag caagggattc accctccgca ggctcagagc aagatagagg 1850

 agctggagca agaaccggag ccggagccgg agccggaacc ggagcccgag 1900

 cccgagcccg agccggagca gctctgacct ggagctgagg cagccagcag 1950

 atctcagcag cccagtccaa ataaacgtcc tgtctagcag c 1991

<210> 1516
<211> 525
<212> PRT
<213> Homo sapien

<400> 1516
 Met Trp Glu Ala Gln Phe Leu Gly Leu Leu Phe Leu Gln Pro Leu
   1               5                  10                  15

 Trp Val Ala Pro Val Lys Pro Leu Gln Pro Gly Ala Glu Val Pro
                  20                  25                  30

 Val Val Trp Ala Gln Glu Gly Ala Pro Ala Gln Leu Pro Cys Ser
                  35                  40                  45

 Pro Thr Ile Pro Leu Gln Asp Leu Ser Leu Leu Arg Arg Ala Gly
                  50                  55                  60

 Val Thr Trp Gln His Gln Pro Asp Ser Gly Pro Pro Ala Ala Ala
                  65                  70                  75

 Pro Gly His Pro Leu Ala Pro Gly Pro His Pro Ala Ala Pro Ser
                  80                  85                  90

 Ser Trp Gly Pro Arg Pro Arg Arg Tyr Thr Val Leu Ser Val Gly
                  95                 100                 105

 Pro Gly Gly Leu Arg Ser Gly Arg Leu Pro Leu Gln Pro Arg Val
                 110                 115                 120

 Gln Leu Asp Glu Arg Gly Arg Gln Arg Gly Asp Phe Ser Leu Trp
                 125                 130                 135

 Leu Arg Pro Ala Arg Arg Ala Asp Ala Gly Glu Tyr Arg Ala Ala
                 140                 145                 150

 Val His Leu Arg Asp Arg Ala Leu Ser Cys Arg Leu Arg Leu Arg
                 155                 160                 165

 Leu Gly Gln Ala Ser Met Thr Ala Ser Pro Pro Gly Ser Leu Arg
                 170                 175                 180

 Ala Ser Asp Trp Val Ile Leu Asn Cys Ser Phe Ser Arg Pro Asp
                 185                 190                 195

 Arg Pro Ala Ser Val His Trp Phe Arg Asn Arg Gly Gln Gly Arg
                 200                 205                 210

 Val Pro Val Arg Glu Ser Pro His His His Leu Ala Glu Ser Phe
                 215                 220                 225

 Leu Phe Leu Pro Gln Val Ser Pro Met Asp Ser Gly Pro Trp Gly
                 230                 235                 240

 Cys Ile Leu Thr Tyr Arg Asp Gly Phe Asn Val Ser Ile Met Tyr
                 245                 250                 255

 Asn Leu Thr Val Leu Gly Leu Glu Pro Pro Thr Pro Leu Thr Val
                 260                 265                 270

 Tyr Ala Gly Ala Gly Ser Arg Val Gly Leu Pro Cys Arg Leu Pro
                 275                 280                 285

 Ala Gly Val Gly Thr Arg Ser Phe Leu Thr Ala Lys Trp Thr Pro
                 290                 295                 300

 Pro Gly Gly Gly Pro Asp Leu Leu Val Thr Gly Asp Asn Gly Asp
                 305                 310                 315

 Phe Thr Leu Arg Leu Glu Asp Val Ser Gln Ala Gln Ala Gly Thr
                 320                 325                 330

 Tyr Thr Cys His Ile His Leu Gln Glu Gln Gln Leu Asn Ala Thr
                 335                 340                 345

 Val Thr Leu Ala Ile Ile Thr Val Thr Pro Lys Ser Phe Gly Ser
                 350                 355                 360

 Pro Gly Ser Leu Gly Lys Leu Leu Cys Glu Val Thr Pro Val Ser
                 365                 370                 375

 Gly Gln Glu Arg Phe Val Trp Ser Ser Leu Asp Thr Pro Ser Gln
                 380                 385                 390

 Arg Ser Phe Ser Gly Pro Trp Leu Glu Ala Gln Glu Ala Gln Leu
                 395                 400                 405

 Leu Ser Gln Pro Trp Gln Cys Gln Leu Tyr Gln Gly Glu Arg Leu
                 410                 415                 420

 Leu Gly Ala Ala Val Tyr Phe Thr Glu Leu Ser Ser Pro Gly Ala
                 425                 430                 435

 Gln Arg Ser Gly Arg Ala Pro Gly Ala Leu Pro Ala Gly His Leu
                 440                 445                 450

 Leu Leu Phe Leu Thr Leu Gly Val Leu Ser Leu Leu Leu Leu Val
                 455                 460                 465

 Thr Gly Ala Phe Gly Phe His Leu Trp Arg Arg Gln Trp Arg Pro
                 470                 475                 480

 Arg Arg Phe Ser Ala Leu Glu Gln Gly Ile His Pro Pro Gln Ala
                 485                 490                 495

 Gln Ser Lys Ile Glu Glu Leu Glu Gln Glu Pro Glu Pro Glu Pro
                 500                 505                 510

 Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Gln Leu
                 515                 520                 525

<210> 1517
<211> 2559
<212> DNA
<213> Homo sapien

<400> 1517
 agattcgcag tggtcgcttc ttctccttgg atttgttaag gattccaagt 50

 aactcttatt tggagagaag acgatctgca cttcgcattt tggcattgac 100

 atttaatttt agggtccttt atatagaagg gagactacat gaatgtgtaa 150

 gatcttggag gaagacagca gagagagaga gagagagcag agatcccagg 200

 gttaaaagtt ggagaaattt cacagtacat catccaaaag aggagtccat 250

 gatggaggca gaggtaaact tggagaggac aggaagatgt cacccaagcg 300

 catagctaaa agaaggtccc ccccagcaga tgccatcccc aaaagcaaga 350

 aggtgaaggt ctcacacagg tcccacagca cagaacccgg cttggtgctg 400

 acactaggcc agggcgacgt gggccagctg gggctgggtg agaatgtgat 450

 ggagaggaag aagccggccc tggtatccat tccggaggat gttgtgcagg 500

 ctgaggctgg gggcatgcac accgtgtgtc taagcaaaag tggccaggtc 550

 tattccttcg gctgcaatga tgagggtgcc ctgggaaggg acacatcagt 600

 ggagggctcg gagatggtcc ctgggaaagt ggagctgcaa gagaaggtgg 650

 tacaggtgtc agcaggagac agtcacacag cagccctcac cgatgatggc 700

 cgtgtcttcc tctggggctc cttccgggac aataacggtg tgattggact 750

 gttggagccc atgaagaaga gcatggtgcc tgtgcaggtg cagctggatg 800

 tgcctgtggt aaaggtggcc tcaggaaacg accacttggt gatgctgaca 850

 gctgatggtg acctctacac cttgggctgc ggggaacagg gccagctagg 900

 ccgtgtgcct gagttatttg ccaaccgtgg tggccggcaa ggcctcgaac 950

 gactcctggt ccccaagtgt gtgatgctga aatccagggg aagccggggc 1000

 cacgtgagat tccaggatgc cttttgtggt gcctatttca cctttgccat 1050

 ctcccatgag ggccacgtgt acggcttcgg cctctccaac taccatcagc 1100

 ttggaactcc gggcacagaa tcttgcttca taccccagaa cctaacatcc 1150

 ttcaagaatt ccaccaagtc ctgggtgggc ttctctggtg gccagcacca 1200

 tacagtctgc atggattcgg aaggaaaagc atacagcctg ggccgggctg 1250

 agtatgggcg gctgggcctt ggagagggtg ctgaggagaa gagcataccc 1300

 accctcatct ccaggctgcc tgctgtctcc tcggtggctt gtggggcctc 1350

 tgtggggtat gctgtgacca aggatggtcg tgttttcgcc tggggcatgg 1400

 gcaccaacta ccagctgggc acagggcagg atgaggacgc ctggagccct 1450

 gtggagatga tgggcaaaca gctggagaac cgtgtggtct tatctgtgtc 1500

 cagcgggggc cagcatacag tcttattagt caaggacaaa gaacagagct 1550

 gatgaagcct ctgagggcct ggcttctgtc ctgcacaacc tccctcacag 1600

 aacagggaag cagtgacagc tgcagatggc agcgggcctc tccccagccc 1650

 tgagcactgt gtcagttcct gccttttctc atcagcagaa cagaatcctt 1700

 ttcctctttt ccttcctcct ctttggaatt ttcctgggac ctacagaata 1750

 aaggggggga tggacagggg gttttcaaaa ggaacatggc tcactcagag 1800

 ctatatggtt agacgtttct ccccttttcc ctaccttcca tggtcctggt 1850

 tggccctggc tttgcctact agaaaaccaa aacttccccc ctggggtttt 1900

 gtgcccactc tctgagaagt tggggctcca tcaagcccca ttctagtcat 1950

 gtgccccttt cctgtcccta acagtccaca ggcaaacaaa tggtacagtc 2000

 ataagagcca tctgtcacgg acccacgccc agaggaacgt gcagaaaaaa 2050

 gcagagctac atggctgtgg gcaactataa gccaaatatt tggctcagaa 2100

 caggtgtcca tgggacaaaa aagaacgatc ctccacttga ccaagaaaaa 2150

 agtgattctc ccagaagcac aaagcatact cttgcccctc aggtgttgct 2200

 tgtgtacatc gtacccatcc attcggcttc acctgcagcc aacggcctgg 2250

 aatcgcaaag agacaccact ctgggcagag cagagcaggg tatggggtgg 2300

 ggagagaggg tggagggttt tataaacaaa cttaacagca atattgaaag 2350

 gaggtggggg attgagggag ggacagagtg ttggagggcc agagactagt 2400

 cctgagatgg aaacagcaac ttgtacagtg gctgagaaaa taggatatag 2450

 ttttgatttt tttaattgta aaatattttg gagggagaac aaaatctttt 2500

 aacattttga ataaatttag agttttataa aatagaaaaa aaaaaaaaaa 2550

 aaaaaaaaa 2559

<210> 1518
<211> 421
<212> PRT
<213> Homo sapien

<400> 1518
 Met Ser Pro Lys Arg Ile Ala Lys Arg Arg Ser Pro Pro Ala Asp
   1               5                  10                  15

 Ala Ile Pro Lys Ser Lys Lys Val Lys Val Ser His Arg Ser His
                  20                  25                  30

 Ser Thr Glu Pro Gly Leu Val Leu Thr Leu Gly Gln Gly Asp Val
                  35                  40                  45

 Gly Gln Leu Gly Leu Gly Glu Asn Val Met Glu Arg Lys Lys Pro
                  50                  55                  60

 Ala Leu Val Ser Ile Pro Glu Asp Val Val Gln Ala Glu Ala Gly
                  65                  70                  75

 Gly Met His Thr Val Cys Leu Ser Lys Ser Gly Gln Val Tyr Ser
                  80                  85                  90

 Phe Gly Cys Asn Asp Glu Gly Ala Leu Gly Arg Asp Thr Ser Val
                  95                 100                 105

 Glu Gly Ser Glu Met Val Pro Gly Lys Val Glu Leu Gln Glu Lys
                 110                 115                 120

 Val Val Gln Val Ser Ala Gly Asp Ser His Thr Ala Ala Leu Thr
                 125                 130                 135

 Asp Asp Gly Arg Val Phe Leu Trp Gly Ser Phe Arg Asp Asn Asn
                 140                 145                 150

 Gly Val Ile Gly Leu Leu Glu Pro Met Lys Lys Ser Met Val Pro
                 155                 160                 165

 Val Gln Val Gln Leu Asp Val Pro Val Val Lys Val Ala Ser Gly
                 170                 175                 180

 Asn Asp His Leu Val Met Leu Thr Ala Asp Gly Asp Leu Tyr Thr
                 185                 190                 195

 Leu Gly Cys Gly Glu Gln Gly Gln Leu Gly Arg Val Pro Glu Leu
                 200                 205                 210

 Phe Ala Asn Arg Gly Gly Arg Gln Gly Leu Glu Arg Leu Leu Val
                 215                 220                 225

 Pro Lys Cys Val Met Leu Lys Ser Arg Gly Ser Arg Gly His Val
                 230                 235                 240

 Arg Phe Gln Asp Ala Phe Cys Gly Ala Tyr Phe Thr Phe Ala Ile
                 245                 250                 255

 Ser His Glu Gly His Val Tyr Gly Phe Gly Leu Ser Asn Tyr His
                 260                 265                 270

 Gln Leu Gly Thr Pro Gly Thr Glu Ser Cys Phe Ile Pro Gln Asn
                 275                 280                 285

 Leu Thr Ser Phe Lys Asn Ser Thr Lys Ser Trp Val Gly Phe Ser
                 290                 295                 300

 Gly Gly Gln His His Thr Val Cys Met Asp Ser Glu Gly Lys Ala
                 305                 310                 315

 Tyr Ser Leu Gly Arg Ala Glu Tyr Gly Arg Leu Gly Leu Gly Glu
                 320                 325                 330

 Gly Ala Glu Glu Lys Ser Ile Pro Thr Leu Ile Ser Arg Leu Pro
                 335                 340                 345

 Ala Val Ser Ser Val Ala Cys Gly Ala Ser Val Gly Tyr Ala Val
                 350                 355                 360

 Thr Lys Asp Gly Arg Val Phe Ala Trp Gly Met Gly Thr Asn Tyr
                 365                 370                 375

 Gln Leu Gly Thr Gly Gln Asp Glu Asp Ala Trp Ser Pro Val Glu
                 380                 385                 390

 Met Met Gly Lys Gln Leu Glu Asn Arg Val Val Leu Ser Val Ser
                 395                 400                 405

 Ser Gly Gly Gln His Thr Val Leu Leu Val Lys Asp Lys Glu Gln
                 410                 415                 420

 Ser


<210> 1519
<211> 2251
<212> DNA
<213> Homo sapien

<400> 1519
 ctgggatcag gcaaccctct cacctcagcc tcccaagtag ctgggactac 50

 aggtgcacgc taccatgcct ggctaatttt tttgtacttt tagtaaagac 100

 ggggttttgt catgttgctc gggctagcct caaactcctg ggctcaagcg 150

 atcctccctc ctcggcctcc caaagtgctg ggattacagg cttgagccac 200

 cgcacctggc cttccccatt tttctcttaa tccatatctc agacaggaat 250

 ctgtatctct cactctacag atcattctgt aggcactatg ctaaactgac 300

 accagtttca aatttagtcc ttaattgatc ttggccttta ggtgagcaaa 350

 gttacagtgg taaattacgc tccttcgctt acaaaatctc ttgcttggta 400

 tttattcccc aggggttaca tagaatagag tggaggcagt agacatggag 450

 aaatcctatc ttttaagaaa gaaaaaaatg ggcatttttc tcatggggaa 500

 ggatttttat ttttcaaata ggtgtttgaa ctgtaatgat ttcatgacat 550

 ctgcctaacg gttttgtttc tttgtcttac agaaacaaac agtcgttgct 600

 gtcaaaaaag agatcatgta ttaccaacag gccttgatga ggtccacagt 650

 gaagtcttct gtgtccctgg gagggattgt gaaatacagt gagcagttct 700

 catccaacga tgccatcatg tcaggctgcc tccccagcaa cccctggatc 750

 accgatgaca cccagttctg ggacttaaat gccaaattgg tggaaatccc 800

 aaccaagatg cgagtggaac gatgggcctt caacttcagc gaattgatcc 850

 gagaccccaa aggtcgacag agcttccagt acttcctcaa gaaagaattc 900

 agtggagaga atctgggatt ctgggaagcc tgcgaggatc tgaagtatgg 950

 agatcagtcc aaagtcaagg agaaagcaga ggagatttac aagctgttcc 1000

 tggccccggg ggcgaggcgc tggatcaaca tagatggcaa aaccatggac 1050

 atcaccgtga aggggctgaa gcacccccac cgctatgtgc tggacgccgc 1100

 acaaacccac atttacatgc tcatgaagaa ggattcttat gctcgctatt 1150

 taaaatctcc gatctataag gacatgcagg ccaaagctat tgaccctcag 1200

 gaaacaacca agaaaagctc caccctccct tttatgcggc gtcacctgcg 1250

 ctccagccca agccctgtca tcctgagaca gctggaagag gaagccaagg 1300

 cccgagaagc agccaacact gtggacatca cccagccggg ccagcacatg 1350

 gctcccagcc cccatctgac cgtgtacacc gggacctgca tgcccccgtc 1400

 tccttctagc cccttctcct cctcctgccg ctcccccagg aagcctttcg 1450

 cctcacccag ccgcttcatc cggcgaccaa ccatctgccc ctcaccgatc 1500

 ctagtggtct tggatagctc atcgggcttg gagcagaaag gggagtgcag 1550

 ctggtctggt gccaaccctg ggccctctgt caccgacagc agcgaggcct 1600

 cccgcgacac ctcctggact cgcagccggc ccagggcccc tctcaaggcc 1650

 cgcatggctc tgtccttcag caggtttctg agacgaggct gtctggcttc 1700

 acctgtcttt gccagggtgt cacccaagtg ccctgctgtg tcccacggga 1750

 gggtgcagcc cctgggggac gtgggccagc agctgccacg attgaaatcc 1800

 aagagagtag caaacttttt ccagatcaaa atggatgtgc ccacggggag 1850

 cgggacctgc ttgatggact cggaggatgc tggaacagga gagtcgggtg 1900

 accgggccac agaaaaggag gtcatctgcc cctgggagag cctgtaagga 1950

 aagaggcagg ctgagttggg ggctctggac caggaagatg ttctgacaga 2000

 tgccatggta tgggccacag gacacacttg ctcgagaacc aaagtgcatt 2050

 tgggtgacat ttgaagattg gggagacaag atggggtaga ttgtggcaaa 2100

 gaatgctctg gctggttacc aggggccaac tccttctcct cttcctgacc 2150

 ctccctcccc tgggcagaag aaacgcatgt ggaccagaag actttccctg 2200

 ctgccttaaa accaataaaa ggttaaattg aaaaaaaaaa aaaaaaaaaa 2250

 a 2251

<210> 1520
<211> 443
<212> PRT
<213> Homo sapien

<400> 1520
 Met Tyr Tyr Gln Gln Ala Leu Met Arg Ser Thr Val Lys Ser Ser
   1               5                  10                  15

 Val Ser Leu Gly Gly Ile Val Lys Tyr Ser Glu Gln Phe Ser Ser
                  20                  25                  30

 Asn Asp Ala Ile Met Ser Gly Cys Leu Pro Ser Asn Pro Trp Ile
                  35                  40                  45

 Thr Asp Asp Thr Gln Phe Trp Asp Leu Asn Ala Lys Leu Val Glu
                  50                  55                  60

 Ile Pro Thr Lys Met Arg Val Glu Arg Trp Ala Phe Asn Phe Ser
                  65                  70                  75

 Glu Leu Ile Arg Asp Pro Lys Gly Arg Gln Ser Phe Gln Tyr Phe
                  80                  85                  90

 Leu Lys Lys Glu Phe Ser Gly Glu Asn Leu Gly Phe Trp Glu Ala
                  95                 100                 105

 Cys Glu Asp Leu Lys Tyr Gly Asp Gln Ser Lys Val Lys Glu Lys
                 110                 115                 120

 Ala Glu Glu Ile Tyr Lys Leu Phe Leu Ala Pro Gly Ala Arg Arg
                 125                 130                 135

 Trp Ile Asn Ile Asp Gly Lys Thr Met Asp Ile Thr Val Lys Gly
                 140                 145                 150

 Leu Lys His Pro His Arg Tyr Val Leu Asp Ala Ala Gln Thr His
                 155                 160                 165

 Ile Tyr Met Leu Met Lys Lys Asp Ser Tyr Ala Arg Tyr Leu Lys
                 170                 175                 180

 Ser Pro Ile Tyr Lys Asp Met Gln Ala Lys Ala Ile Asp Pro Gln
                 185                 190                 195

 Glu Thr Thr Lys Lys Ser Ser Thr Leu Pro Phe Met Arg Arg His
                 200                 205                 210

 Leu Arg Ser Ser Pro Ser Pro Val Ile Leu Arg Gln Leu Glu Glu
                 215                 220                 225

 Glu Ala Lys Ala Arg Glu Ala Ala Asn Thr Val Asp Ile Thr Gln
                 230                 235                 240

 Pro Gly Gln His Met Ala Pro Ser Pro His Leu Thr Val Tyr Thr
                 245                 250                 255

 Gly Thr Cys Met Pro Pro Ser Pro Ser Ser Pro Phe Ser Ser Ser
                 260                 265                 270

 Cys Arg Ser Pro Arg Lys Pro Phe Ala Ser Pro Ser Arg Phe Ile
                 275                 280                 285

 Arg Arg Pro Thr Ile Cys Pro Ser Pro Ile Leu Val Val Leu Asp
                 290                 295                 300

 Ser Ser Ser Gly Leu Glu Gln Lys Gly Glu Cys Ser Trp Ser Gly
                 305                 310                 315

 Ala Asn Pro Gly Pro Ser Val Thr Asp Ser Ser Glu Ala Ser Arg
                 320                 325                 330

 Asp Thr Ser Trp Thr Arg Ser Arg Pro Arg Ala Pro Leu Lys Ala
                 335                 340                 345

 Arg Met Ala Leu Ser Phe Ser Arg Phe Leu Arg Arg Gly Cys Leu
                 350                 355                 360

 Ala Ser Pro Val Phe Ala Arg Val Ser Pro Lys Cys Pro Ala Val
                 365                 370                 375

 Ser His Gly Arg Val Gln Pro Leu Gly Asp Val Gly Gln Gln Leu
                 380                 385                 390

 Pro Arg Leu Lys Ser Lys Arg Val Ala Asn Phe Phe Gln Ile Lys
                 395                 400                 405

 Met Asp Val Pro Thr Gly Ser Gly Thr Cys Leu Met Asp Ser Glu
                 410                 415                 420

 Asp Ala Gly Thr Gly Glu Ser Gly Asp Arg Ala Thr Glu Lys Glu
                 425                 430                 435

 Val Ile Cys Pro Trp Glu Ser Leu
                 440

<210> 1521
<211> 4967
<212> DNA
<213> Homo sapien

<400> 1521
 aaatgaagtc aaaatgccaa taagaccaga tctccagcag ttggaaaaat 50

 gcattgatga tgctttaaga aaaaatgatt tcaaaccttt gaaaacactt 100

 ttgcaaattg atatttgtga agatgtgaag attaaatgca gcaaacagtt 150

 tttccacaag gtggacaacc ttatatgcag ggaacttaat aaagaggata 200

 tccacaatgt ttcagccatt ttggtttctg ttggaagatg tggcaaaaat 250

 atcagtgtat tggggcaagc tggacttcta acgatgataa aacaaggact 300

 aatacaaaag atggttgcct ggtttgaaaa atccaaggac attattcaga 350

 gtcaaggaaa ttcaaaagat gaagctgttc taaatatgat agaagactta 400

 gttgatcttc tgctggtcat acatgatgtc agtgatgaag gtaaaaaaca 450

 agtagtggaa agtttcgtac ctcgcatttg ttccctggtt attgactcaa 500

 gagtgaatat ttgtattcag caagagatta taaaaaaaat gaatgctatg 550

 cttgacaaaa tgcctcaaga tgcccggaaa atactctcta accaagaaat 600

 gttaattctc atgagtagta tgggagaaag gattttagat gctggagatt 650

 atgacttaca ggtagccatt gtagaagctt tgtgtagaat gaccacagaa 700

 aaacaaagac aagaactggc acatcagtgg ttttcaatgg attttattgc 750

 taaggcattt aaaagaatta aggactctga atttgaaaca gattgcagga 800

 tatttctcaa ccttgtaaat ggcatgcttg gagacaaaag aagggtcttt 850

 acatttcctt gtttatcagc atttcttgat aaatatgagc tgcaaatacc 900

 atcagatgaa aaacttgagg aattttggat tgattttaat cttgggagtc 950

 agactctctc attctacatt gctggagata atgatgatca tcaatgggaa 1000

 gcagttactg tgccagagga aaaagtacaa atatacagca ttgaagtgag 1050

 agaatcaaag aagctactga caataattct gaaaaataca gtaaaaatta 1100

 gcaaaagaga agggaaagaa ttgcttttgt attttgacgc atcactagaa 1150

 atcactaatg taactcaaaa aatttttggt gcaactaaac atagggaatc 1200

 tatcagaaaa caaggtattt cagttgccaa aacgtcgctg catatacttt 1250

 ttgacgcaag tggatcacag attctagtgc cagaaagtca aatctcacca 1300

 gtcggagaag agctcgttag tttaaaggaa aaatcaaagt ccccaaagga 1350

 atttgctaaa ccttcaaaat atatcaaaaa cagtgacaaa gggaatagaa 1400

 ataatagtca gcttgagaaa actactccta gcaaaagaaa aatgtctgaa 1450

 gcatcaatga ttgtttctgg tgcagataga tacactatga gaagtccagt 1500

 gcttttcagc aacacatcaa taccaccacg aagaagaaga attaaaccac 1550

 cactgcaaat gacgagctct gcagagaaac ctagtgtttc tcaaacatca 1600

 gaaaatagag tggataatgc tgcatcactg aaatctagat catcagaagg 1650

 aagacataga agagataata tagacaaaca tatcaaaact gctaagtgtg 1700

 tagaaaacac agaaaataag aatgttgaat tcccaaacca aaattttagt 1750

 gaactccagg atgttatacc agattcacag gcagcggaaa aaagagatca 1800

 tactatatta cctggtgttt tagacaacat ctgtggaaat aaaatacaca 1850

 gcaaatgggc atgttggaca cctgtaacaa acattgaact atgtaataac 1900

 caaagagcaa gtacttcgtc aggagacaca ttgaatcaag atattgttat 1950

 aaataaaaaa cttactaaac aaaaatcatc ctcttcaata tctgatcata 2000

 attctgaagg aacaggaaaa gtgaaatata agaaagaaca aaccgaccat 2050

 atcaaaatag ataaagcaga agtagaagtt tgcaggaaac acaatcagca 2100

 acaaaatcat cctaaatatt cagggcagaa aaatactgaa aatgccaagc 2150

 agagtgattg gcctgttgaa tctgaaacta cttttaaatc ggttctccta 2200

 aataagacaa ttgaagaatc gctgatatat aggaagaaat acatattgtc 2250

 aaaagatgtg aatactgcta cttgcgataa aaatccatct gctagcaaaa 2300

 atgtgcaaag tcatagaaaa gcagagaaag aattgacttc tgagcttaat 2350

 tcctgggatt cgaaacaaaa aaaaatgaga gaaaagtcaa aagggaaaga 2400

 atttaccaat gtagcagaat ccttgataag ccaaatcaat aaaagataca 2450

 aaacaaaaga tgacatcaag tctacaagaa aattaaagga gtctttgatt 2500

 aacagtggtt tttcaaacaa acctgttgta caactcagta aggaaaaagt 2550

 tcagaaaaaa agctacagaa aactgaagac tacctttgtt aatgttactt 2600

 ctgaatgccc agtgaatgat gtttacaatt ttaatttgaa tggagctgat 2650

 gaccctatca taaaacttgg aatccaagag tttcaagcta cagctaaaga 2700

 agcttgtgcg gataggtcaa ttagattggt aggtccaagg aatcatgatg 2750

 aacttaaatc ttctgtcaaa acaaaagata aaaaaattat aacaaatcat 2800

 caaaagaaaa atctgtttag tgatactgaa acagagtaca gatgtgatga 2850

 cagcaagact gatattagct ggctaagaga accgaaatca aaaccacagc 2900

 taatagacta tagcagaaat aaaaatgtga agaatcataa aagtggaaaa 2950

 tcaagatcat ccttggaaaa gggacagcca agctctaaaa tgacacccag 3000

 taaaaatatc acaaaaaaga tggacaagac aattccggaa ggaagaatca 3050

 gacttccacg aaaagcaacc aaaacaaaaa aaaactataa agatctctca 3100

 aattcagaat cagagtgtga acaagaattt tcacattcat ttaaagagaa 3150

 cataccagta aaggaggaga atatccattc cagaatgaaa acggtaaagc 3200

 taccaaagaa acaacagaaa gtcttctgtg ctgaaacaga aaaggaacta 3250

 tcaaaacaat ggaaaaactc atctctacta aaagatgcta tacgagataa 3300

 ttgccttgac ttatctccca gatctttatc tggcagtcca tcatctatag 3350

 aagtaacgag atgtatagag aaaataacag aaaaggattt tactcaggat 3400

 tatgactgca taacaaaatc tatatcacct tatccaaaaa cttcatcact 3450

 tgaatcctta aatagtaaca gtggagttgg aggtacaata aagtcaccca 3500

 aaaacaatga gaaaaacttc ctgtgtgcaa gtgaaagttg ttcaccaact 3550

 ccacgaccac tgtttttggc cagacatact ccaactaaga gtaatactat 3600

 tgtaaataga aaaaaaataa gttctctggt acttacacaa gaaacacaaa 3650

 acagtaacag ctattcagat gtaagcagat atagttcaga agaacggttt 3700

 atggaaattg aatctccaca tatcaatgaa aattatatac aaagcaaaag 3750

 agaggaaagt catttagcat cttcattatc caagtctagt gaaggaagag 3800

 agaaaacgtg gtttgacatg ccctgtgatg ctactcatgt atcaggcccc 3850

 acccaacatc ttagtcgcaa aagaatatat atagaagata atctaagtaa 3900

 ttccaatgaa gtagaaatgg aagagaaagg agaaaggaga gcaaacttgc 3950

 ttcccaaaaa actgtgtaaa attgaagatg cagatcatca tatccacaaa 4000

 atgtctgaaa gtgtatcttc attatcaaca aatgactttt ctattccttg 4050

 ggagacctgg caaaatgaat ttgcagggat agagatgact tatgagactt 4100

 acgagaggct caattcagaa tttaagagaa ggaataatat ccgacataaa 4150

 atgttgagtt attttactac gcagtcttgg aaaacagctc agcaacatct 4200

 gagaacaatg aatcatcaaa gtcaggactc taggattaaa aaacttgata 4250

 aattccaatt cattatcata gaggagctgg agaattttga aaaagattca 4300

 cagtctttaa aagatttgga aaaggaattt gtggactttt gggaaaagat 4350

 atttcagaag ttcagtgcat atcaaaaaag cgaacaacag aggcttcatc 4400

 ttttgaaaac ttcattggct aaaagtgtct tctgtaatac tgatagtgaa 4450

 gaaactgttt ttacatccga gatgtgtttg atgaaagaag atatgaaagt 4500

 gctgcaagac aggcttctta aggacatgct agaagaggag cttcttaatg 4550

 tacgcagaga actgatgtca gtattcatgt ctcatgaaag aaatgctaat 4600

 gtgtgaaatc tagtttttat caccatactt tatctaatta ttattctctg 4650

 tatataactg aggaaataag aatagtccta caaagagaaa aatatacatg 4700

 tcaccgaagc aagtgtaccc tttataggaa ccctcaaatt aaaaaaaaat 4750

 gtcttttaat ggatgagagg gaaccactat aacatgagtc caagcccaga 4800

 agacttctgt ctatacaata ttttttttta attttggaga taaaagcttt 4850

 aagaaacttt ttgagttaat tatactcata aaatgagttt ctttaataaa 4900

 ttaaatttta ttgtgtaaaa tgtattatta cataaaatgt gtttttgaat 4950

 caatgcagtt tgggccg 4967

<210> 1522
<211> 1530
<212> PRT
<213> Homo sapien

<400> 1522
 Met Pro Ile Arg Pro Asp Leu Gln Gln Leu Glu Lys Cys Ile Asp
   1               5                  10                  15

 Asp Ala Leu Arg Lys Asn Asp Phe Lys Pro Leu Lys Thr Leu Leu
                  20                  25                  30

 Gln Ile Asp Ile Cys Glu Asp Val Lys Ile Lys Cys Ser Lys Gln
                  35                  40                  45

 Phe Phe His Lys Val Asp Asn Leu Ile Cys Arg Glu Leu Asn Lys
                  50                  55                  60

 Glu Asp Ile His Asn Val Ser Ala Ile Leu Val Ser Val Gly Arg
                  65                  70                  75

 Cys Gly Lys Asn Ile Ser Val Leu Gly Gln Ala Gly Leu Leu Thr
                  80                  85                  90

 Met Ile Lys Gln Gly Leu Ile Gln Lys Met Val Ala Trp Phe Glu
                  95                 100                 105

 Lys Ser Lys Asp Ile Ile Gln Ser Gln Gly Asn Ser Lys Asp Glu
                 110                 115                 120

 Ala Val Leu Asn Met Ile Glu Asp Leu Val Asp Leu Leu Leu Val
                 125                 130                 135

 Ile His Asp Val Ser Asp Glu Gly Lys Lys Gln Val Val Glu Ser
                 140                 145                 150

 Phe Val Pro Arg Ile Cys Ser Leu Val Ile Asp Ser Arg Val Asn
                 155                 160                 165

 Ile Cys Ile Gln Gln Glu Ile Ile Lys Lys Met Asn Ala Met Leu
                 170                 175                 180

 Asp Lys Met Pro Gln Asp Ala Arg Lys Ile Leu Ser Asn Gln Glu
                 185                 190                 195

 Met Leu Ile Leu Met Ser Ser Met Gly Glu Arg Ile Leu Asp Ala
                 200                 205                 210

 Gly Asp Tyr Asp Leu Gln Val Ala Ile Val Glu Ala Leu Cys Arg
                 215                 220                 225

 Met Thr Thr Glu Lys Gln Arg Gln Glu Leu Ala His Gln Trp Phe
                 230                 235                 240

 Ser Met Asp Phe Ile Ala Lys Ala Phe Lys Arg Ile Lys Asp Ser
                 245                 250                 255

 Glu Phe Glu Thr Asp Cys Arg Ile Phe Leu Asn Leu Val Asn Gly
                 260                 265                 270

 Met Leu Gly Asp Lys Arg Arg Val Phe Thr Phe Pro Cys Leu Ser
                 275                 280                 285

 Ala Phe Leu Asp Lys Tyr Glu Leu Gln Ile Pro Ser Asp Glu Lys
                 290                 295                 300

 Leu Glu Glu Phe Trp Ile Asp Phe Asn Leu Gly Ser Gln Thr Leu
                 305                 310                 315

 Ser Phe Tyr Ile Ala Gly Asp Asn Asp Asp His Gln Trp Glu Ala
                 320                 325                 330

 Val Thr Val Pro Glu Glu Lys Val Gln Ile Tyr Ser Ile Glu Val
                 335                 340                 345

 Arg Glu Ser Lys Lys Leu Leu Thr Ile Ile Leu Lys Asn Thr Val
                 350                 355                 360

 Lys Ile Ser Lys Arg Glu Gly Lys Glu Leu Leu Leu Tyr Phe Asp
                 365                 370                 375

 Ala Ser Leu Glu Ile Thr Asn Val Thr Gln Lys Ile Phe Gly Ala
                 380                 385                 390

 Thr Lys His Arg Glu Ser Ile Arg Lys Gln Gly Ile Ser Val Ala
                 395                 400                 405

 Lys Thr Ser Leu His Ile Leu Phe Asp Ala Ser Gly Ser Gln Ile
                 410                 415                 420

 Leu Val Pro Glu Ser Gln Ile Ser Pro Val Gly Glu Glu Leu Val
                 425                 430                 435

 Ser Leu Lys Glu Lys Ser Lys Ser Pro Lys Glu Phe Ala Lys Pro
                 440                 445                 450

 Ser Lys Tyr Ile Lys Asn Ser Asp Lys Gly Asn Arg Asn Asn Ser
                 455                 460                 465

 Gln Leu Glu Lys Thr Thr Pro Ser Lys Arg Lys Met Ser Glu Ala
                 470                 475                 480

 Ser Met Ile Val Ser Gly Ala Asp Arg Tyr Thr Met Arg Ser Pro
                 485                 490                 495

 Val Leu Phe Ser Asn Thr Ser Ile Pro Pro Arg Arg Arg Arg Ile
                 500                 505                 510

 Lys Pro Pro Leu Gln Met Thr Ser Ser Ala Glu Lys Pro Ser Val
                 515                 520                 525

 Ser Gln Thr Ser Glu Asn Arg Val Asp Asn Ala Ala Ser Leu Lys
                 530                 535                 540

 Ser Arg Ser Ser Glu Gly Arg His Arg Arg Asp Asn Ile Asp Lys
                 545                 550                 555

 His Ile Lys Thr Ala Lys Cys Val Glu Asn Thr Glu Asn Lys Asn
                 560                 565                 570

 Val Glu Phe Pro Asn Gln Asn Phe Ser Glu Leu Gln Asp Val Ile
                 575                 580                 585

 Pro Asp Ser Gln Ala Ala Glu Lys Arg Asp His Thr Ile Leu Pro
                 590                 595                 600

 Gly Val Leu Asp Asn Ile Cys Gly Asn Lys Ile His Ser Lys Trp
                 605                 610                 615

 Ala Cys Trp Thr Pro Val Thr Asn Ile Glu Leu Cys Asn Asn Gln
                 620                 625                 630

 Arg Ala Ser Thr Ser Ser Gly Asp Thr Leu Asn Gln Asp Ile Val
                 635                 640                 645

 Ile Asn Lys Lys Leu Thr Lys Gln Lys Ser Ser Ser Ser Ile Ser
                 650                 655                 660

 Asp His Asn Ser Glu Gly Thr Gly Lys Val Lys Tyr Lys Lys Glu
                 665                 670                 675

 Gln Thr Asp His Ile Lys Ile Asp Lys Ala Glu Val Glu Val Cys
                 680                 685                 690

 Arg Lys His Asn Gln Gln Gln Asn His Pro Lys Tyr Ser Gly Gln
                 695                 700                 705

 Lys Asn Thr Glu Asn Ala Lys Gln Ser Asp Trp Pro Val Glu Ser
                 710                 715                 720

 Glu Thr Thr Phe Lys Ser Val Leu Leu Asn Lys Thr Ile Glu Glu
                 725                 730                 735

 Ser Leu Ile Tyr Arg Lys Lys Tyr Ile Leu Ser Lys Asp Val Asn
                 740                 745                 750

 Thr Ala Thr Cys Asp Lys Asn Pro Ser Ala Ser Lys Asn Val Gln
                 755                 760                 765

 Ser His Arg Lys Ala Glu Lys Glu Leu Thr Ser Glu Leu Asn Ser
                 770                 775                 780

 Trp Asp Ser Lys Gln Lys Lys Met Arg Glu Lys Ser Lys Gly Lys
                 785                 790                 795

 Glu Phe Thr Asn Val Ala Glu Ser Leu Ile Ser Gln Ile Asn Lys
                 800                 805                 810

 Arg Tyr Lys Thr Lys Asp Asp Ile Lys Ser Thr Arg Lys Leu Lys
                 815                 820                 825

 Glu Ser Leu Ile Asn Ser Gly Phe Ser Asn Lys Pro Val Val Gln
                 830                 835                 840

 Leu Ser Lys Glu Lys Val Gln Lys Lys Ser Tyr Arg Lys Leu Lys
                 845                 850                 855

 Thr Thr Phe Val Asn Val Thr Ser Glu Cys Pro Val Asn Asp Val
                 860                 865                 870

 Tyr Asn Phe Asn Leu Asn Gly Ala Asp Asp Pro Ile Ile Lys Leu
                 875                 880                 885

 Gly Ile Gln Glu Phe Gln Ala Thr Ala Lys Glu Ala Cys Ala Asp
                 890                 895                 900

 Arg Ser Ile Arg Leu Val Gly Pro Arg Asn His Asp Glu Leu Lys
                 905                 910                 915

 Ser Ser Val Lys Thr Lys Asp Lys Lys Ile Ile Thr Asn His Gln
                 920                 925                 930

 Lys Lys Asn Leu Phe Ser Asp Thr Glu Thr Glu Tyr Arg Cys Asp
                 935                 940                 945

 Asp Ser Lys Thr Asp Ile Ser Trp Leu Arg Glu Pro Lys Ser Lys
                 950                 955                 960

 Pro Gln Leu Ile Asp Tyr Ser Arg Asn Lys Asn Val Lys Asn His
                 965                 970                 975

 Lys Ser Gly Lys Ser Arg Ser Ser Leu Glu Lys Gly Gln Pro Ser
                 980                 985                 990

 Ser Lys Met Thr Pro Ser Lys Asn Ile Thr Lys Lys Met Asp Lys
                 995                1000                1005

 Thr Ile Pro Glu Gly Arg Ile Arg Leu Pro Arg Lys Ala Thr Lys
                1010                1015                1020

 Thr Lys Lys Asn Tyr Lys Asp Leu Ser Asn Ser Glu Ser Glu Cys
                1025                1030                1035

 Glu Gln Glu Phe Ser His Ser Phe Lys Glu Asn Ile Pro Val Lys
                1040                1045                1050

 Glu Glu Asn Ile His Ser Arg Met Lys Thr Val Lys Leu Pro Lys
                1055                1060                1065

 Lys Gln Gln Lys Val Phe Cys Ala Glu Thr Glu Lys Glu Leu Ser
                1070                1075                1080

 Lys Gln Trp Lys Asn Ser Ser Leu Leu Lys Asp Ala Ile Arg Asp
                1085                1090                1095

 Asn Cys Leu Asp Leu Ser Pro Arg Ser Leu Ser Gly Ser Pro Ser
                1100                1105                1110

 Ser Ile Glu Val Thr Arg Cys Ile Glu Lys Ile Thr Glu Lys Asp
                1115                1120                1125

 Phe Thr Gln Asp Tyr Asp Cys Ile Thr Lys Ser Ile Ser Pro Tyr
                1130                1135                1140

 Pro Lys Thr Ser Ser Leu Glu Ser Leu Asn Ser Asn Ser Gly Val
                1145                1150                1155

 Gly Gly Thr Ile Lys Ser Pro Lys Asn Asn Glu Lys Asn Phe Leu
                1160                1165                1170

 Cys Ala Ser Glu Ser Cys Ser Pro Thr Pro Arg Pro Leu Phe Leu
                1175                1180                1185

 Ala Arg His Thr Pro Thr Lys Ser Asn Thr Ile Val Asn Arg Lys
                1190                1195                1200

 Lys Ile Ser Ser Leu Val Leu Thr Gln Glu Thr Gln Asn Ser Asn
                1205                1210                1215

 Ser Tyr Ser Asp Val Ser Arg Tyr Ser Ser Glu Glu Arg Phe Met
                1220                1225                1230

 Glu Ile Glu Ser Pro His Ile Asn Glu Asn Tyr Ile Gln Ser Lys
                1235                1240                1245

 Arg Glu Glu Ser His Leu Ala Ser Ser Leu Ser Lys Ser Ser Glu
                1250                1255                1260

 Gly Arg Glu Lys Thr Trp Phe Asp Met Pro Cys Asp Ala Thr His
                1265                1270                1275

 Val Ser Gly Pro Thr Gln His Leu Ser Arg Lys Arg Ile Tyr Ile
                1280                1285                1290

 Glu Asp Asn Leu Ser Asn Ser Asn Glu Val Glu Met Glu Glu Lys
                1295                1300                1305

 Gly Glu Arg Arg Ala Asn Leu Leu Pro Lys Lys Leu Cys Lys Ile
                1310                1315                1320

 Glu Asp Ala Asp His His Ile His Lys Met Ser Glu Ser Val Ser
                1325                1330                1335

 Ser Leu Ser Thr Asn Asp Phe Ser Ile Pro Trp Glu Thr Trp Gln
                1340                1345                1350

 Asn Glu Phe Ala Gly Ile Glu Met Thr Tyr Glu Thr Tyr Glu Arg
                1355                1360                1365

 Leu Asn Ser Glu Phe Lys Arg Arg Asn Asn Ile Arg His Lys Met
                1370                1375                1380

 Leu Ser Tyr Phe Thr Thr Gln Ser Trp Lys Thr Ala Gln Gln His
                1385                1390                1395

 Leu Arg Thr Met Asn His Gln Ser Gln Asp Ser Arg Ile Lys Lys
                1400                1405                1410

 Leu Asp Lys Phe Gln Phe Ile Ile Ile Glu Glu Leu Glu Asn Phe
                1415                1420                1425

 Glu Lys Asp Ser Gln Ser Leu Lys Asp Leu Glu Lys Glu Phe Val
                1430                1435                1440

 Asp Phe Trp Glu Lys Ile Phe Gln Lys Phe Ser Ala Tyr Gln Lys
                1445                1450                1455

 Ser Glu Gln Gln Arg Leu His Leu Leu Lys Thr Ser Leu Ala Lys
                1460                1465                1470

 Ser Val Phe Cys Asn Thr Asp Ser Glu Glu Thr Val Phe Thr Ser
                1475                1480                1485

 Glu Met Cys Leu Met Lys Glu Asp Met Lys Val Leu Gln Asp Arg
                1490                1495                1500

 Leu Leu Lys Asp Met Leu Glu Glu Glu Leu Leu Asn Val Arg Arg
                1505                1510                1515

 Glu Leu Met Ser Val Phe Met Ser His Glu Arg Asn Ala Asn Val
                1520                1525                1530

<210> 1523
<211> 1327
<212> DNA
<213> Homo sapien

<400> 1523
 ggtcgacgac gtggcagccg ggatgcacta ggcaaagcca gctgggctcc 50

 tgagtccggt gggtacttgg agaacttact acgtctagct ggaggattgt 100

 aaatgtacca atcagcatgc tgtgtctagc tcaagaactc aagctccatg 150

 aggagatgtt tcattgtcga gagcagtcat gatggcctgc actccacaca 200

 atgcaacaga gtgaaagagc aggttctgct tctttggtgt agtcctgaag 250

 cttcctaaga aacttcacat caggtgatgg ataggagcaa ccctgtaaaa 300

 ccagccttag actatttttt aaacaggctg gtgaattacc agatctccgt 350

 caagtgcagt aaccagttca agttggaagt gtgtcttttg aatgcagaaa 400

 acaaagtcgt ggacaaccag gctgggaccc agggccagct gaaggtgctg 450

 ggtgccaacc tctggtggcc gtacctgatg cacgaacacc ccgcctacct 500

 ctactcgtgg gaggatggtg attgctcaca ccaaagcctt ggacccctcc 550

 cagcctgtga cctttgtgac caactccacc tacgcagcag acaagggggc 600

 tctgtatgtg gatgtgatcc gtgtgaacag ctactactct tggtatcgca 650

 actacgggca cctggagttg attcagctgc agctggccgc ccagtttgag 700

 aattggtgta agacatcaca atcccattat tcagagcgcg tatggagtgg 750

 aaacgcttgt agggtttcac cagtctttcc cagggaactc cgatgaagtg 800

 ttccaacaaa atgagcgagt gaaccaagaa gaggatgaca ttagatccag 850

 gagatacaac agaggagata atctccagga tgcctgtgaa gaaagatccc 900

 tggatcccag gatgattata ggacaagttg ttcataatcc agcaggccag 950

 aagacttcca gggaaactca ttcaaggagg tgaaaatgat ggatgactcc 1000

 tccaagatga aaatggacca gccgcagtgc tcacgcctgt aataccagca 1050

 ctttgggagg ctgaggcagg cggatcactt gaggtcagga gtttgaaact 1100

 agcctggcca acgtggcaaa actccatctc tattaaaaat acaaaaatta 1150

 gccaggcata gtggtgcatg cctgtagtcc cagctacttg ggatgccgag 1200

 gcaggaagaa ttgcttgaac ctgggaggca gagtctgcag tgagccgaga 1250

 tcatgccact gcactccagc ctgggtgaca gagccactcc gtctcaaaaa 1300

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 1327

<210> 1524
<211> 140
<212> PRT
<213> Homo sapien

<400> 1524
 Met Asp Arg Ser Asn Pro Val Lys Pro Ala Leu Asp Tyr Phe Leu
   1               5                  10                  15

 Asn Arg Leu Val Asn Tyr Gln Ile Ser Val Lys Cys Ser Asn Gln
                  20                  25                  30

 Phe Lys Leu Glu Val Cys Leu Leu Asn Ala Glu Asn Lys Val Val
                  35                  40                  45

 Asp Asn Gln Ala Gly Thr Gln Gly Gln Leu Lys Val Leu Gly Ala
                  50                  55                  60

 Asn Leu Trp Trp Pro Tyr Leu Met His Glu His Pro Ala Tyr Leu
                  65                  70                  75

 Tyr Ser Trp Glu Asp Gly Asp Cys Ser His Gln Ser Leu Gly Pro
                  80                  85                  90

 Leu Pro Ala Cys Asp Leu Cys Asp Gln Leu His Leu Arg Ser Arg
                  95                 100                 105

 Gln Gly Gly Ser Val Cys Gly Cys Asp Pro Cys Glu Gln Leu Leu
                 110                 115                 120

 Leu Leu Val Ser Gln Leu Arg Ala Pro Gly Val Asp Ser Ala Ala
                 125                 130                 135

 Ala Gly Arg Pro Val
                 140

<210> 1525
<211> 624
<212> DNA
<213> Homo sapien

<400> 1525
 ggcgggccgc tcccacttcg gcacgagggg cacgaggtaa atcttttctg 50

 cttactgaaa aggaagagtc tgatgattag ttactgatcc tctttgcatt 100

 tgtaaagctt tggagatatt gaatcatgtt accatttctg tttttttcca 150

 ccctgttttc ttccatattt actgaagctc agaagcagta ttgggtctgc 200

 aactcatccg atgcaagtat ttcatacacc tactgtgata aaatgcaata 250

 cccaatttca attaatgtta acccctgtat agaattgaaa ggatccaaag 300

 gattattgca cattttctac attccaagga gagatttaaa gcaattatat 350

 ttcaatctct atataactgt caacaccatg aatcttccaa agcgcaaaga 400

 agttatttgc cgaggatctg atgacgatta ctctttttgc agagctctga 450

 agggagagac tgtgaataca acaatatcat tctccttcaa gggaataaaa 500

 ttttctaagg gaaaatacaa atgtgttgtt gaagctattt ctgggagccc 550

 agaagaaatg ctcttttgct tggagtttgt catcctacac caacctaatt 600

 caaattagaa taaattgagt attt 624

<210> 1526
<211> 160
<212> PRT
<213> Homo sapien

<400> 1526
 Met Leu Pro Phe Leu Phe Phe Ser Thr Leu Phe Ser Ser Ile Phe
   1               5                  10                  15

 Thr Glu Ala Gln Lys Gln Tyr Trp Val Cys Asn Ser Ser Asp Ala
                  20                  25                  30

 Ser Ile Ser Tyr Thr Tyr Cys Asp Lys Met Gln Tyr Pro Ile Ser
                  35                  40                  45

 Ile Asn Val Asn Pro Cys Ile Glu Leu Lys Gly Ser Lys Gly Leu
                  50                  55                  60

 Leu His Ile Phe Tyr Ile Pro Arg Arg Asp Leu Lys Gln Leu Tyr
                  65                  70                  75

 Phe Asn Leu Tyr Ile Thr Val Asn Thr Met Asn Leu Pro Lys Arg
                  80                  85                  90

 Lys Glu Val Ile Cys Arg Gly Ser Asp Asp Asp Tyr Ser Phe Cys
                  95                 100                 105

 Arg Ala Leu Lys Gly Glu Thr Val Asn Thr Thr Ile Ser Phe Ser
                 110                 115                 120

 Phe Lys Gly Ile Lys Phe Ser Lys Gly Lys Tyr Lys Cys Val Val
                 125                 130                 135

 Glu Ala Ile Ser Gly Ser Pro Glu Glu Met Leu Phe Cys Leu Glu
                 140                 145                 150

 Phe Val Ile Leu His Gln Pro Asn Ser Asn
                 155                 160

<210> 1527
<211> 2809
<212> DNA
<213> Homo sapien

<400> 1527
 agattcgcgg ccgcgtcgac ggtgcgccca ccggtcccgc cgggcgcccg 50

 cgggacgcgc cgccagggcc ctctccgccg ggggctcggc gctcgcccac 100

 ctcttccaaa tttaaccatt acctaaatcc gaagggaaat gagcaaacct 150

 ctcggattgg gtgtcaaggt ctcctccggg ctggggctga gcaagccctc 200

 ggagtgaccg tgggtgacag cggctccagg gactcttggg gcgcagtggg 250

 gaaagtgccg gaccaccatg ccgcgctcat ttctcgtcaa aagcaagaag 300

 gctcacagct accaccagcc gcgctcccca ggaccagact attccctccg 350

 tttagagaat gtaccggcgc ctagccgagc agacagcact tcaaatgcag 400

 gcggggcgaa agcggagccc cgggaccgtt tgtcccccga atcgcagctg 450

 accgaagccc cagacagagc ctccgcatcc cccagacagc tgcgaagcag 500

 cgtctgcgaa cggagctcgg agtttgagga cttctggagg cccccgtcac 550

 cctccgcgtc tccagcctcg gagaagtcaa tgtgcccatc gctggacgaa 600

 gcccagccct tccccctgcc tttcaaaccg tactcatgga gcggcctggc 650

 gggttctgac ctgcggcacc tggtgcagag ctaccgaccg tgtggggccc 700

 tggagcgtgg cgctggcctg ggcctcttct gtgaacccgc cccggagcct 750

 ggccacccgg ccgcgctgta cggcccgaag cgggctgccg gcggcgcggg 800

 ggccggggcg ccagggaact gcatcgcagg ggccggtgcc accgctggcc 850

 ctggcctagg gctctacggc gacttcgggt ctgcggcagc cgggctgtat 900

 gaaaagccca cggcagcggc gggcttgctg taccccgagc gtggccaccg 950

 gctgcacgca aacaaaggcg ctggcgtcaa ggtggagtcg gagctgctgt 1000

 gcacccgcct gctgctgggc ggcggctcct acaagtgcat caagtgcagc 1050

 aaggtgtttt ccacgccgca cgggctcgag gtgcacgtgc gcaggtccca 1100

 cagcggtacc agaccctttg cctgcgagat gtgcggcaag accttcgggc 1150

 acgcggtgag cctggagcag cacaaagccg tgcactcgca ggaacggagc 1200

 tttgactgta agatctgtgg gaagagcttc aagaggtcat ccacactgtc 1250

 cacacacctg cttatccact cagacactcg gccctacccc tgtcagtact 1300

 gtggcaagag gttccaccag aagtcagaca tgaagaaaca cactttcatc 1350

 cacactggtg agaagcttca caagtgccag gtgtgcggca aggcattcag 1400

 ccagagctcc aacctcatca cccacagccg caaacacaca ggcttcaagc 1450

 ccttcggctg cgacctctgt gggaagggtt tccagaggaa ggtggacctc 1500

 cgaaggcacc gggagacgca gcatgggctc aaatgagcac cctggctggc 1550

 tgcaagcagc agctacacaa cactacagag ggcagcctcc ctgcttgcca 1600

 ccactctgct ccctgcttgc ctccactccc ttctgacttt ccagacccca 1650

 ggtccagtct gcagatccta ccaggttgct cctccttcgc cttacctcct 1700

 ggagctgcca gaagaaatga ggtacctttt caaagtgcag ccgagagtga 1750

 gaaccaagtg actccctagg cttcggacac aaataggctc ctctacacct 1800

 gaagacaaag gcaaagtcaa atggggacca gaataaatct tagaccccac 1850

 agtccttccc atttccagcc ttaatctaca gacaggaatg cccttcaggt 1900

 ttcttccttc ccccttcttg acctacccca gatatttgtg tggaagagga 1950

 ggaatcacca tttacaaggt ggacaaatgc taatattttt atctagaaag 2000

 aagagtgagt gttaactttt atttttttcc ttctgggggg tctgttgact 2050

 cctttctttt gggtgctgcc tataaatctt ggaggaatca tttctcctcc 2100

 tcaaaaactg attcagaaac tgacttgggg aaggaattta atactttgaa 2150

 gtcatgagat gcaccatcga ggctaccccc aagaagaagc agaagagaag 2200

 ttggtaatga gaggggatta gaggtcctcc cttcagtagg gctgtgaaaa 2250

 cctcatcact ggaggtaaaa gcacaagcaa tgcctgtgga caagatgtca 2300

 ttcattcact cagcaaatgt tcatggatca ccggctacca agtaccaggc 2350

 accatgttag gtattgggga agagagactg aagtcacaac ccctgactgc 2400

 tcctcaaaag ctaacggttg cacctccaag tggctgggtc tgttcttact 2450

 cttggaggga attctgagaa gacagcacag aattgtaaac cttccctttt 2500

 gacccttttg gattttatca ggtgtaaaca aaaagctgaa cagttacttc 2550

 aaagatatgt gtgtatattc agttttttat tgttaagctg atattttaaa 2600

 gatttctgag ctagcaggca tgtgggaagg aaggctctgt cttcaactct 2650

 ttgaccctcc atgtgtacca tagagggggg aaaggtggta ttttcacttt 2700

 gatgaggttg gtaaatgttt ttagatcttc tggtaagcat tatgtttgtt 2750

 aatacatatt tattagagtg atgttttaag ttaataaagt attaagagta 2800

 aaaaaaaaa 2809

<210> 1528
<211> 422
<212> PRT
<213> Homo sapien

<400> 1528
 Met Pro Arg Ser Phe Leu Val Lys Ser Lys Lys Ala His Ser Tyr
   1               5                  10                  15

 His Gln Pro Arg Ser Pro Gly Pro Asp Tyr Ser Leu Arg Leu Glu
                  20                  25                  30

 Asn Val Pro Ala Pro Ser Arg Ala Asp Ser Thr Ser Asn Ala Gly
                  35                  40                  45

 Gly Ala Lys Ala Glu Pro Arg Asp Arg Leu Ser Pro Glu Ser Gln
                  50                  55                  60

 Leu Thr Glu Ala Pro Asp Arg Ala Ser Ala Ser Pro Arg Gln Leu
                  65                  70                  75

 Arg Ser Ser Val Cys Glu Arg Ser Ser Glu Phe Glu Asp Phe Trp
                  80                  85                  90

 Arg Pro Pro Ser Pro Ser Ala Ser Pro Ala Ser Glu Lys Ser Met
                  95                 100                 105

 Cys Pro Ser Leu Asp Glu Ala Gln Pro Phe Pro Leu Pro Phe Lys
                 110                 115                 120

 Pro Tyr Ser Trp Ser Gly Leu Ala Gly Ser Asp Leu Arg His Leu
                 125                 130                 135

 Val Gln Ser Tyr Arg Pro Cys Gly Ala Leu Glu Arg Gly Ala Gly
                 140                 145                 150

 Leu Gly Leu Phe Cys Glu Pro Ala Pro Glu Pro Gly His Pro Ala
                 155                 160                 165

 Ala Leu Tyr Gly Pro Lys Arg Ala Ala Gly Gly Ala Gly Ala Gly
                 170                 175                 180

 Ala Pro Gly Asn Cys Ile Ala Gly Ala Gly Ala Thr Ala Gly Pro
                 185                 190                 195

 Gly Leu Gly Leu Tyr Gly Asp Phe Gly Ser Ala Ala Ala Gly Leu
                 200                 205                 210

 Tyr Glu Lys Pro Thr Ala Ala Ala Gly Leu Leu Tyr Pro Glu Arg
                 215                 220                 225

 Gly His Arg Leu His Ala Asn Lys Gly Ala Gly Val Lys Val Glu
                 230                 235                 240

 Ser Glu Leu Leu Cys Thr Arg Leu Leu Leu Gly Gly Gly Ser Tyr
                 245                 250                 255

 Lys Cys Ile Lys Cys Ser Lys Val Phe Ser Thr Pro His Gly Leu
                 260                 265                 270

 Glu Val His Val Arg Arg Ser His Ser Gly Thr Arg Pro Phe Ala
                 275                 280                 285

 Cys Glu Met Cys Gly Lys Thr Phe Gly His Ala Val Ser Leu Glu
                 290                 295                 300

 Gln His Lys Ala Val His Ser Gln Glu Arg Ser Phe Asp Cys Lys
                 305                 310                 315

 Ile Cys Gly Lys Ser Phe Lys Arg Ser Ser Thr Leu Ser Thr His
                 320                 325                 330

 Leu Leu Ile His Ser Asp Thr Arg Pro Tyr Pro Cys Gln Tyr Cys
                 335                 340                 345

 Gly Lys Arg Phe His Gln Lys Ser Asp Met Lys Lys His Thr Phe
                 350                 355                 360

 Ile His Thr Gly Glu Lys Leu His Lys Cys Gln Val Cys Gly Lys
                 365                 370                 375

 Ala Phe Ser Gln Ser Ser Asn Leu Ile Thr His Ser Arg Lys His
                 380                 385                 390

 Thr Gly Phe Lys Pro Phe Gly Cys Asp Leu Cys Gly Lys Gly Phe
                 395                 400                 405

 Gln Arg Lys Val Asp Leu Arg Arg His Arg Glu Thr Gln His Gly
                 410                 415                 420

 Leu Lys


<210> 1529
<211> 3522
<212> DNA
<213> Homo sapien

<400> 1529
 gccatttgaa gcagaatcca aaccatgaat tgtagagaat tacccttgac 50

 cctttgggtg cttatatctg taagcactgc agaatcttgt acttcacgtc 100

 cccacattac tgtggttgaa ggggaacctt tctatctgaa acattgctcg 150

 tgttcacttg cacatgagat tgaaacaacc accaaaagct ggtacaaaag 200

 cagtggatca caggaacatg tggagctgaa cccaaggagt tcctcgagaa 250

 ttgctttgca tgattgtgtt ttggagtttt ggccagttga gttgaatgac 300

 acaggatctt actttttcca aatgaaaaat tatactcaga aatggaaatt 350

 aaatgtcatc agaagaaata aacacagctg tttcactgaa agacaagtaa 400

 ctagtaaaat tgtggaagtt aaaaaatttt ttcagataac ctgtgaaaac 450

 agttactatc aaacactggt caacagcaca tcattgtata agaactgtaa 500

 aaagctacta ctggagaaca ataaaaaccc aacgataaag aagaacgccg 550

 agtttgaaga tcaggggtat tactcctgcg tgcatttcct tcatcataat 600

 ggaaaactat ttaatatcac caaaaccttc aatataacaa tagtggaaga 650

 tcgcagtaat atagttccgg ttcttcttgg accaaagctt aaccatgttg 700

 cagtggaatt aggaaaaaac gtaaggctca actgctctgc tttgctgaat 750

 gaagaggatg taatttattg gatgttcggg gaagaaaatg gatcggatcc 800

 taatatacat gaagagaaag aaatgagaat tatgactcca gaaggcaaat 850

 ggcatgcttc aaaagtattg agaattgaaa atattggtga aagcaatcta 900

 aatgttttat ataattgcac tgtggccagc acgggaggca cagacaccaa 950

 aagcttcatc ttggtgagaa aagcagacat ggctgatatc ccaggccacg 1000

 tcttcacaag aggaatgatc atagctgttt tgatcttggt ggcagtagtg 1050

 tgcctagtga ctgtgtgtgt catttataga gttgacttgg ttctatttta 1100

 tagacattta acgagaagag atgaaacatt aacagatgga aaaacatatg 1150

 atgcttttgt gtcttaccta aaagaatgcc gacctgaaaa tggagaggag 1200

 cacacctttg ctgtggagat tttgcccagg gtgttggaga aacattttgg 1250

 gtataagtta tgcatatttg aaagggatgt agtgcctgga ggagctgttg 1300

 ttgatgaaat ccactcactg atagagaaaa gccgaagact aatcattgtc 1350

 ctaagtaaaa gttatatgtc taatgaggtc aggtatgaac ttgaaagtgg 1400

 actccatgaa gcattggtgg aaagaaaaat taaaataatc ttaattgaat 1450

 ttacacctgt tactgacttc acattcttgc cccaatcact aaagcttttg 1500

 aaatctcaca gagttctgaa gtggaaggcc gataaatctc tttcttataa 1550

 ctcaaggttc tggaagaacc ttctttactt aatgcctgca aaaacagtca 1600

 agccaggtag agacgaaccg gaagtcttgc ctgttctttc cgagtcttaa 1650

 tcttcagaaa cagtgaacgc caaaaagaac tcaagatatt ctggggactg 1700

 agcatatgaa cctgttcata acaaaggctg tgactcgaaa taattaactt 1750

 tgtcaaaatc ctgctcacaa tttgaagatg aaacttgtca ttaggttggc 1800

 gggaatgaga ctaaagattg cgctgtgggc tgtggtcacg tgctcccaga 1850

 agacctggaa ttcaaaagaa atggagctat tctttttctc cctctttcat 1900

 aactggatgc agctgctcat actcaatccc atattcagca agtgtgaagc 1950

 tggacgtgat gcaaaataac cgatgcccta caaaaagggc gcatctttaa 2000

 gagttttaat gccagtgctt aattcgaatg aggggatttt aagtgtctga 2050

 agaggcattt tctagggacc agtgggtgac tgagtaactg aaatgctgct 2100

 ttcactccct aacaccatgg atctggttgt gcataggatg tgggaggagg 2150

 ggctggcagg gccgccttca gaggctgcag ggcctcagcc tcaggatgca 2200

 tttaatgtat cctggccaca gttgcagcca acggttcttg aaagctcggt 2250

 aaggccctgc aacgcagagc ctgcttatgt ggatctattt atgggaactt 2300

 cttaaaagga ccccagaata gctctttatc tttcacaaga gacacaaatt 2350

 ctaattgagt taattatctg ggcctttcac tttggatgct ctgaaacatt 2400

 tgttgatttt gtgtgaatgt ttatatcaaa atgtttgcca ggttgtatta 2450

 gccattgaat agcaaaaaac tgatagttac ttgcttgttt tttaaaaatt 2500

 acatattaaa aatgcccttg gcataaggca gcatggtgtg gcagttaaga 2550

 gatgggctgt gcagcccatc ctgagctcca gtcctgagtt tgctacttac 2600

 ttctgtggcc tctggaacct tatccaacct cttggtgctt cagtttcctc 2650

 atctgtgaaa ttagaattta taataattgc acctacctcc caggggtaac 2700

 taaatgaata aatataataa agtacttaca gtggttcctg acacagactc 2750

 agcactccgt cagtgttgcc atgactattt ttattatcat tattaatgat 2800

 tacttagatc aattatttag cagtggacta atggaagcta cagagcaggg 2850

 aagggaagca gatctaggga ggaaggcagt tttgatttga ggaggtttgc 2900

 acatgtagag aagcatactg gagaagcata tccagagggc gaaagatatc 2950

 tctccattgt gcatctgcct cttttgacgt tggaagacac atgtcttact 3000

 ccccaaaggg agcccagcac tgggagcctt cttgatgatc tcaaaaataa 3050

 tagctattca agaaaatcac caagtgactg tgaaaccgtc agttcggaag 3100

 gctggttaga acatgtggga gcaacatgaa tgttctacaa aagtttaaag 3150

 cagagattgt ttcaaatggg tgtagtagat attactgaaa accaaaaaag 3200

 agtgagattg tcagtgtaag aatgtgattt aatgtttgta gtgcttacaa 3250

 ttttgtgtac caactggatg actaaaaaga gtaaaataat ttaattaata 3300

 gctcatattt tatgtgtgaa aacatgttag tgaacatata taatcaaaat 3350

 agatttcatt gctattgcat agtctctaat acatagaatg attttgcttt 3400

 tctcttttat tatacttgct ttaaaatact tgaaatatat tttgcattaa 3450

 atgcatttca agttaaatgt cttaaatgta tacattagat gtgtgtttta 3500

 aaatgcataa aacacgttga aa 3522

<210> 1530
<211> 541
<212> PRT
<213> Homo sapien

<400> 1530
 Met Asn Cys Arg Glu Leu Pro Leu Thr Leu Trp Val Leu Ile Ser
   1               5                  10                  15

 Val Ser Thr Ala Glu Ser Cys Thr Ser Arg Pro His Ile Thr Val
                  20                  25                  30

 Val Glu Gly Glu Pro Phe Tyr Leu Lys His Cys Ser Cys Ser Leu
                  35                  40                  45

 Ala His Glu Ile Glu Thr Thr Thr Lys Ser Trp Tyr Lys Ser Ser
                  50                  55                  60

 Gly Ser Gln Glu His Val Glu Leu Asn Pro Arg Ser Ser Ser Arg
                  65                  70                  75

 Ile Ala Leu His Asp Cys Val Leu Glu Phe Trp Pro Val Glu Leu
                  80                  85                  90

 Asn Asp Thr Gly Ser Tyr Phe Phe Gln Met Lys Asn Tyr Thr Gln
                  95                 100                 105

 Lys Trp Lys Leu Asn Val Ile Arg Arg Asn Lys His Ser Cys Phe
                 110                 115                 120

 Thr Glu Arg Gln Val Thr Ser Lys Ile Val Glu Val Lys Lys Phe
                 125                 130                 135

 Phe Gln Ile Thr Cys Glu Asn Ser Tyr Tyr Gln Thr Leu Val Asn
                 140                 145                 150

 Ser Thr Ser Leu Tyr Lys Asn Cys Lys Lys Leu Leu Leu Glu Asn
                 155                 160                 165

 Asn Lys Asn Pro Thr Ile Lys Lys Asn Ala Glu Phe Glu Asp Gln
                 170                 175                 180

 Gly Tyr Tyr Ser Cys Val His Phe Leu His His Asn Gly Lys Leu
                 185                 190                 195

 Phe Asn Ile Thr Lys Thr Phe Asn Ile Thr Ile Val Glu Asp Arg
                 200                 205                 210

 Ser Asn Ile Val Pro Val Leu Leu Gly Pro Lys Leu Asn His Val
                 215                 220                 225

 Ala Val Glu Leu Gly Lys Asn Val Arg Leu Asn Cys Ser Ala Leu
                 230                 235                 240

 Leu Asn Glu Glu Asp Val Ile Tyr Trp Met Phe Gly Glu Glu Asn
                 245                 250                 255

 Gly Ser Asp Pro Asn Ile His Glu Glu Lys Glu Met Arg Ile Met
                 260                 265                 270

 Thr Pro Glu Gly Lys Trp His Ala Ser Lys Val Leu Arg Ile Glu
                 275                 280                 285

 Asn Ile Gly Glu Ser Asn Leu Asn Val Leu Tyr Asn Cys Thr Val
                 290                 295                 300

 Ala Ser Thr Gly Gly Thr Asp Thr Lys Ser Phe Ile Leu Val Arg
                 305                 310                 315

 Lys Ala Asp Met Ala Asp Ile Pro Gly His Val Phe Thr Arg Gly
                 320                 325                 330

 Met Ile Ile Ala Val Leu Ile Leu Val Ala Val Val Cys Leu Val
                 335                 340                 345

 Thr Val Cys Val Ile Tyr Arg Val Asp Leu Val Leu Phe Tyr Arg
                 350                 355                 360

 His Leu Thr Arg Arg Asp Glu Thr Leu Thr Asp Gly Lys Thr Tyr
                 365                 370                 375

 Asp Ala Phe Val Ser Tyr Leu Lys Glu Cys Arg Pro Glu Asn Gly
                 380                 385                 390

 Glu Glu His Thr Phe Ala Val Glu Ile Leu Pro Arg Val Leu Glu
                 395                 400                 405

 Lys His Phe Gly Tyr Lys Leu Cys Ile Phe Glu Arg Asp Val Val
                 410                 415                 420

 Pro Gly Gly Ala Val Val Asp Glu Ile His Ser Leu Ile Glu Lys
                 425                 430                 435

 Ser Arg Arg Leu Ile Ile Val Leu Ser Lys Ser Tyr Met Ser Asn
                 440                 445                 450

 Glu Val Arg Tyr Glu Leu Glu Ser Gly Leu His Glu Ala Leu Val
                 455                 460                 465

 Glu Arg Lys Ile Lys Ile Ile Leu Ile Glu Phe Thr Pro Val Thr
                 470                 475                 480

 Asp Phe Thr Phe Leu Pro Gln Ser Leu Lys Leu Leu Lys Ser His
                 485                 490                 495

 Arg Val Leu Lys Trp Lys Ala Asp Lys Ser Leu Ser Tyr Asn Ser
                 500                 505                 510

 Arg Phe Trp Lys Asn Leu Leu Tyr Leu Met Pro Ala Lys Thr Val
                 515                 520                 525

 Lys Pro Gly Arg Asp Glu Pro Glu Val Leu Pro Val Leu Ser Glu
                 530                 535                 540

 Ser


<210> 1531
<211> 9372
<212> DNA
<213> Homo sapien

<400> 1531
 tgaataattg aactttgttt atttctccat atttttgcag tggtaattcc 50

 attataaaac ctaatgaaac aatgttttta tagatggtgt ggaaagactt 100

 ttctgggctc agaggtgaaa ctgacccttg tgtatcagca gcatttctga 150

 ctgactgaga gagtgtagtg attaacagag ttgtgatgtt agttaagaaa 200

 cttagatttg ccattgtagc ttttctacca attagcagat tgtttaactc 250

 actgaaattg taaagtggta gacgtggact tagtcattac tgggcagctt 300

 atgaattgta ttcatttact catgatgtaa aaatggttag tctccacttt 350

 taaggctcta gttctagtgg ctaaataggt acttatttat acagtatgat 400

 aactgctgta ttaaaataca tgtctcaaat gtggaatagt agaagaggtg 450

 aagaaaatca tagtttgagg tagaatactg tttgctggtc ttaaaaactg 500

 tggtattttg gtgattccat aaattaggtc agatacttcc actggaggga 550

 aacagtttaa aggatatatg tgatactatt aatagaatga ggaagacaca 600

 ccagatattt aggagggaat tagcgagctt gaaactaaga gctggtttga 650

 atgagactgg gtcataagtg atttcaagta ccagattaag gcactgagat 700

 tttattttta agcactgaag tcagattttt tccttttaaa agaaaggatt 750

 catgatgaaa tctgcttttt gttttgcaga gagcttggag ataattctgg 800

 tggctgtgtg gagtatgtgt tggaggtatt aaattttcac agtatatata 850

 aggcagcaat tgataggcct ttcacagatt cttctgataa ctacataaag 900

 agacaaaaaa aagaaaaaag agcaaagatc tgtgctgtgt caagtatgac 950

 agccatcact catggctctc cagtaggagg gaacgacagc cagggccagg 1000

 ttcttgatgg ccagtctcag catctcttcc aacagaacca gacttcatca 1050

 cctgattctt ccaatgagaa ttccgtagca actcctcctc cagaggaaca 1100

 agggcaaggt gatgccccac cacagcatga agatgaagag cctgcatttc 1150

 cacatactga gctggcaaac ctggatgaca tgatcaacag gcctcgatgg 1200

 gtggttcctg ttttgccaaa aggggaatta gaagtgcttt tagaagctgc 1250

 tattgatctt agtgtaaaag gccttgatgt taaaagtgaa gcatgccaac 1300

 gtttttttcg agatggacta acaatatctt tcactaaaat tcttatggat 1350

 gaggctgtga gtggctggaa gtttgaaatt catagatgta ttattaacaa 1400

 tactcatcgc ctagtggagc tttgtgtggc caagttgtcc caagattggt 1450

 ttccacttct agaacttctc gccatggcct taaatcctca ctgcaagttt 1500

 catatctaca atggtacacg tccgtgtgaa ttaatttcct caaatgctca 1550

 gttgcctgaa gaagaattat ttgctcgttc ttcagatcct cgatcaccaa 1600

 aaggttggct agtggatctc atcaataaat ttggcacatt aaatgggttc 1650

 cagattttgc atgatcgttt ttttaatgga tcagcattaa atattcaaat 1700

 aattgcagct cttattaaac catttggaca atgctatgag tttctcagtc 1750

 aacatacact gaaaaagtac ttcattccag ttatagaaat agttccacat 1800

 ttattggaaa acttaactga tgaagaactg aaaaaggagg caaagaatga 1850

 agccaaaaat gatgcccttt caatgattat taaatctttg aagaacttag 1900

 cttcaagaat ttcaggacaa gatgagacta taaaaaattt ggaaattttt 1950

 aggttaaaga tgatactcag attgttgcaa atttcctctt ttaatggaaa 2000

 gatgaatgca ctgaatgaaa taaataaggt tatatctagt gtatcatatt 2050

 atactcatcg gcatagtaat cctgaggagg aagaatggct gacagctgag 2100

 cgaatggcag aatggataca gcaaaataat atcttatcca tagtcttgca 2150

 agacagtctt catcaaccac aatatgtaga aaagctagag aaaattcttc 2200

 gttttgtgat taaagaaaag gctcttacat tacaggacct tgataatatc 2250

 tgggcagcac aggcaggaaa acatgaagcc attgtgaaga atgtacatga 2300

 tctgctagca aagttggctt gggatttttc tcctggacaa cttgatcatc 2350

 tttttgattg ctttaaggca agttggacaa atgcaagtaa aaagcaacgt 2400

 gaaaagctcc ttgagttgat acgccgtctt gcagaagatg ataaagatgg 2450

 tgtgatggca cacaaagtgt tgaaccttct ttggaacctg gctcagagtg 2500

 atgatgtgcc tgtagacatc atggaccttg ctcttagtgc ccacataaaa 2550

 atactagatt atagttgttc ccaggatcga gatgcacaga agatccagtg 2600

 gatagatcac tttatagaag aacttcgcac aaatgacaag tgggtaattc 2650

 ctgctctgaa acaaataaga gaaatttgta gtttgtttgg tgaagcatct 2700

 caaaatttga gtcaaactca gcgaagtccc cacatatttt atcgccatga 2750

 tttaatcaac cagcttcaac aaaatcatgc tttagttact ttggtagcag 2800

 aaaaccttgc aacctacatg aatagcatca gattgtatgc tggagatcat 2850

 gaagactatg atccacaaac agtgaggctt ggaagtcgat acagtcatgt 2900

 tcaagaagtt caagaacgac taaacttcct tagattttta ctgaaggatg 2950

 gccaactgtg gctctgtgct cctcaggcaa aacaaatatg gaagtgctta 3000

 gcagaaaatg cagtttatct ttgtgatcgt gaagcctgtt ttaagtggta 3050

 ttccaagtta atgggggatg aaccagactt ggatcctgat attaataagg 3100

 acttctttga aagtaatgta cttcagcttg atccttccct tttaactgaa 3150

 aatggaatga aatgctttga aagatttttc aaagctgtca attgtcgaga 3200

 aaggaaacta atagcaaaaa gaagatccta tatgatggat gatttggaat 3250

 taattggact agactacctt tggagggttg tgattcagag tagtgacgag 3300

 attgctaaca gagctataga tcttcttaaa gagatataca caaaccttgg 3350

 cccaagatta aaagccaatc aggtggttat ccatgaagac ttcattcagt 3400

 cttgctttga tcgtttaaaa gcatcatatg atacactgtg tgtttttgat 3450

 ggtgacaaaa acagcattaa ttgtgcaaga caagaagcca ttcgaatggt 3500

 tagagtatta actgttataa aagagtacat taatgaatgt gacagtgatt 3550

 atcacaagga aagaatgatt ttacctatgt cgagagcatt ttgtggcaaa 3600

 cacctctctc ttatagttcg gtttccaaac cagggcagac aggttgatga 3650

 gttggatata tggtttcata cgaatgacac aattggttca gtacggcgat 3700

 gtattgttaa tcgtattaaa gccaatgtag cccacaaaaa aattgaactt 3750

 tttgtgggtg gtgagctgat agattctgaa aatgacagaa agctaattgg 3800

 acaattaaac ttaaaagata aatctctaat tacagccaaa cttacacaaa 3850

 taaatttcaa tatgccatca agtcctgata gctcttccga ttcctcaact 3900

 gcatctcctg gaaaccaccg taatcattac aatgatggtc ccaatctaaa 3950

 ggtggaaagt tgtttgcctg gggtgataat gtcagtgcat cccaaataca 4000

 tctctttcct ttggcaattt gcaaacttag gtagcaacct gaatatgcca 4050

 cctcttaaaa atggagcaag agtacttatg aaacttatgc caccagatag 4100

 aacagctgta gaaaaattac gaactgtttg tttggaccat gcaaaccttg 4150

 gagaaggcaa acttagtcca ccccttgact cccttttctt tggtccttct 4200

 gcctcccaag ttctatacct aacagaggta gtttatgcct tgttaatgcc 4250

 tgctggtgtg cctctaactg atgggtcctc tgactttcaa gttcacttct 4300

 tgaaaagtgg tggcttacct cttgtactga gtatgctaat aagaaataac 4350

 ttcttgccaa atacagatat ggaaactcga aggggtgctt atttaaatgc 4400

 tcttaaaata gccaaactgt tgttaactgc gattggctat ggccatgttc 4450

 gagctgtagc agaagcttgt cagccagttg tagatggtac agaccccata 4500

 acacagatta accaagttac tcatgatcaa gcagtggtgc tacaaagtgc 4550

 ccttcagagc attcctaatc cctcatccga gtgcgtactt agaaatgagt 4600

 ccatacttct tgctcaggaa atatctaatg aggcttcaag atatatgcct 4650

 gatatttgtg taattagggc tatacagaaa attatctggg catcagcatg 4700

 tggggcatta ggactatttt ttagcccaaa tgaagaaata actaaaattt 4750

 atcagatgac caccaatgga agcaataagc tggaggtgga agatgaacaa 4800

 gtttgttgtg aagcactgga agtgatgacc ttatgttttg ctttacttcc 4850

 aacagcgttg gatgcactta gtaaagaaaa agcctggcag accttcatca 4900

 ttgacttatt attgcactgt ccaagcaaaa ctgttcgtca gttggcacag 4950

 gagcagttct ttttaatgtg caccagatgt tgcatgggac acaggcctct 5000

 gcttttcttc attactttac tctttaccat actggggagc acagcaagag 5050

 agaagggtaa atattcaggt gattatttca cacttttacg gcaccttctc 5100

 aattatgctt acaatggcaa tattaacata cccaatgctg aagttcttct 5150

 tgtcagtgaa attgattggc tcaaaaggat tagggataat gttaaaaaca 5200

 caggtgaaac aggtgtcgaa gagccaatac tggaaggcca ccttggggta 5250

 acaaaagagt tattggcctt tcaaacttct gagaaaaagt atcactttgg 5300

 ttgtgaaaaa ggaggtgcta atctcattaa agaattaatt gatgatttca 5350

 tctttcccgc atccaaagtt tacctgcagt atttaagaag tggagaacta 5400

 ccagctgagc aggctattcc agtctgtagt tcacccgtta ccatcaatgc 5450

 cggttttgag ctacttgtag cattagctat tggctgtgtg aggaatctca 5500

 aacagatagt agactgtttg actgaaatgt attacatggg cacagcaatt 5550

 actacttgtg aagcacttac tgagtgggaa tatctgcccc ctgttggacc 5600

 ccgcccacca aaaggatttg tgggactcaa aaatgctggt gctacgtgtt 5650

 acatgaactc tgtgatccag cagctataca tgattccttc tatcaggaac 5700

 agtattcttg caattgaagg cacaggtagt gatttacacg atgatatgtt 5750

 cggggatgag aagcaggaca gtgagagtaa tgttgatccc cgagatgatg 5800

 tatttggata tcctcatcaa tttgaagaca agccagcatt aagtaagaca 5850

 gaagatagga aagagtataa tattggtgtc ctaagacacc ttcaggtcat 5900

 ctttggtcat ttagctgctt cccaactaca atactatgta cccagaggat 5950

 tttggaaaca gttcaggctt tggggtgaac ctgttaatct ccgtgaacaa 6000

 catgatgcct tagagttttt taattctttg gtggatagtt tagatgaagc 6050

 tttaaaagct ttaggacacc cggctatact aagtaaagtc ctaggaggct 6100

 cctttgctga tcagaagatc tgccagggct gcccacatag gtttgaatgt 6150

 gaagaatctt ttacaacttt gaatgtggat attagaaatc atcaaaatct 6200

 tcttgactct ttggaacagt atatcaaagg agatttattg gaaggtgcaa 6250

 atgcatatca ttgtgaaaaa tgtgataaaa aggttgacac agtaaagcgc 6300

 ctgctaatta aaaaattgcc tcgggttctt gctatccaac tcaaacgatt 6350

 tgactatgac tgggaaagag aatgtgcaat taaattcaat gattattttg 6400

 aatttcctcg agagctggat atgggacctt acacagtagc aggtgttgca 6450

 aacctggaaa gggataatgt aaactcagaa aatgagttga ttgaacagaa 6500

 agagcagtct gacaatgaaa ctgcaggagg cacaaagtac agacttgtag 6550

 gagtgcttgt acacagtggt caagcaagcg gtgggcatta ttattcttac 6600

 atcattcaaa ggaatggtaa agatgatcag acagatcact ggtataaatt 6650

 tgatgatgga gatgtaacag aatgcaaaat ggatgatgat gaagaaatga 6700

 aaaatcagtg ttttggtgga gagtacatgg gagaagtatt tgatcacatg 6750

 atgaagcgca tgtcatatag gcgacagaag aggtggtgga atgcttacat 6800

 acctttttat gaacaaatgg atatgataga tgaagatgat gagatgataa 6850

 gatacatatc agagctaact attgcaagac cccatcagat cattatgtca 6900

 ccagccattg agagaagtgt acggaaacaa aatgtgaaat ttatgcataa 6950

 ccgattgcaa tatagtttag agtattttca gtttgtgaaa aaactgctta 7000

 catgtaatgg tgtttattta aaccctgctc cagggcagga ttatttgttg 7050

 cctgaagcag aagaaattac tatgattagt attcagcttg ctgctagatt 7100

 cctctttacc actggatttc acaccaagaa aatagttcgt ggtcctgcca 7150

 gtgactggta tgatgcactg tgcgttcttc tccgtcacag caaaaatgta 7200

 cgtttttggt ttactcataa tgtccttttt aatgtatcaa atcgcttctc 7250

 tgaatacctc ctggagtgcc ctagtgcaga agtgaggggt gcatttgcaa 7300

 aacttatagt gtttattgca cacttttcct tgcaagatgg gtcttgtcct 7350

 tctccttttg catctccagg accttctagt caggcatgtg ataacttgag 7400

 cttgagtgac cacttactaa gagccacact aaatctcttg agaagggaag 7450

 tttcagagca tggacatcat ttacagcaat attttaattt gtttgtaatg 7500

 tatgccaatt taggtgtggc agaaaaaaca cagcttctga aattgaatgt 7550

 acctgctacc tttatgcttg tgtctttaga cgagggacca ggtcctccaa 7600

 tcaaatatca gtatgctgaa ttaggcaagt tatattcagt agtgtctcag 7650

 ctgattcgtt gttgcaatgt gtcatcaaca atgcagtctt caatcaatgg 7700

 taatccccct ctccccaatc ctttcggtga ccttaattta tcacagccta 7750

 taatgccaat tcagcagaat gtgttagaca ttttatttgt gagaacaagt 7800

 tatgtgaaga aaattattga agactgcagt aactcagagg ataccatcaa 7850

 attacttcgc ttttgctctt gggagaatcc tcagttctca tctactgtcc 7900

 tcagcgaact tctctggcag gttgcatatt catataccta tgaacttcgg 7950

 ccatatttag atctactttt ccaaatttta ctgattgagg actcctggca 8000

 gactcacaga attcataatg cacttaaagg aattccagat gacagagatg 8050

 ggctgttcga tacaatacag cgctcgaaga atcactatca aaaacgagca 8100

 tatcagtgca taaaatgtat ggtagctcta tttagcagtt gtcctgttgc 8150

 ttaccagatc ttacagggta acggagatct taaaagaaaa tggacctggg 8200

 cagtggaatg gctaggagat gaacttgaaa gaagaccata tactggcaat 8250

 cctcagtata gttacaacaa ttggtctcct ccagtacaaa gcaatgaaac 8300

 agcaaatggt tatttcttag aaagatcaca tagtgctagg atgacacttg 8350

 caaaagcttg tgaactctgt ccagaagagg agccagatga ccaggatgcc 8400

 ccagatgagc atgagccctc tccatcagaa gatgccccat tatatcctca 8450

 ttcacctgcc tctcagtatc aacagaataa tcatgtacat ggacagccat 8500

 atacaggacc agcagcacat cacttgaaca accctcagaa aacaggccaa 8550

 cgaacacaag aaaattatga aggcaatgaa gaagtatcct cacctcagat 8600

 gaaggatcag tgaaaagcaa taattaactg cttcctttat gactatgcac 8650

 taaggtctta tagtccaaac tttctctgtg tctggctagt attgaaaact 8700

 agataaactg ctccaaacca acatggagta aagagcatat tcactggttt 8750

 atttgcagta atttgcaatt tgtcagtgta taagacacat gcagggtgaa 8800

 gtgtacagag ttttgtaaca aatgactggt cctaatctgt aaatgagaaa 8850

 ggtatatata ctatgttaat gtctgactgt taattcttaa gcaagaaact 8900

 ttttttgatg aaaacaagtc agatctacac agtcacacaa ttattttttg 8950

 ttgtgttcac tacattgtgc aattgatatt gcctgctttg agcagtttgg 9000

 tcaacttacc aacttccccc caaaaaaggg aacataaaag agcccatctt 9050

 tgtcagttta caccaatagt ttcttgttaa tccttctttc ctggatatat 9100

 aaggctggtg gtaacttttg aattatatgg ttgatgtgga aaattggcag 9150

 tgtaacattt ctagatactt ttcattacct ttttattctg gtatataggc 9200

 taaccacttt aaagctattc ttatgctgta acagttagca tggcttcaca 9250

 ctgtttgtgt agccaagagg acagaattac atgaatgaca gtgcccagag 9300

 tgacagctgt atattgctca gagcttttat ttcttatacc tagaataaat 9350

 ataaaatggg ggaaaaaaaa aa 9372

<210> 1532
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1532
 Met Thr Ala Ile Thr His Gly Ser Pro Val Gly Gly Asn Asp Ser
   1               5                  10                  15

 Gln Gly Gln Val Leu Asp Gly Gln Ser Gln His Leu Phe Gln Gln
                  20                  25                  30

 Asn Gln Thr Ser Ser Pro Asp Ser Ser Asn Glu Asn Ser Val Ala
                  35                  40                  45

 Thr Pro Pro Pro Glu Glu Gln Gly Gln Gly Asp Ala Pro Pro Gln
                  50                  55                  60

 His Glu Asp Glu Glu Pro Ala Phe Pro His Thr Glu Leu Ala Asn
                  65                  70                  75

 Leu Asp Asp Met Ile Asn Arg Pro Arg Trp Val Val Pro Val Leu
                  80                  85                  90

 Pro Lys Gly Glu Leu Glu Val Leu Leu Glu Ala Ala Ile Asp Leu
                  95                 100                 105

 Ser Val Lys Gly Leu Asp Val Lys Ser Glu Ala Cys Gln Arg Phe
                 110                 115                 120

 Phe Arg Asp Gly Leu Thr Ile Ser Phe Thr Lys Ile Leu Met Asp
                 125                 130                 135

 Glu Ala Val Ser Gly Trp Lys Phe Glu Ile His Arg Cys Ile Ile
                 140                 145                 150

 Asn Asn Thr His Arg Leu Val Glu Leu Cys Val Ala Lys Leu Ser
                 155                 160                 165

 Gln Asp Trp Phe Pro Leu Leu Glu Leu Leu Ala Met Ala Leu Asn
                 170                 175                 180

 Pro His Cys Lys Phe His Ile Tyr Asn Gly Thr Arg Pro Cys Glu
                 185                 190                 195

 Leu Ile Ser Ser Asn Ala Gln Leu Pro Glu Glu Glu Leu Phe Ala
                 200                 205                 210

 Arg Ser Ser Asp Pro Arg Ser Pro Lys Gly Trp Leu Val Asp Leu
                 215                 220                 225

 Ile Asn Lys Phe Gly Thr Leu Asn Gly Phe Gln Ile Leu His Asp
                 230                 235                 240

 Arg Phe Phe Asn Gly Ser Ala Leu Asn Ile Gln Ile Ile Ala Ala
                 245                 250                 255

 Leu Ile Lys Pro Phe Gly Gln Cys Tyr Glu Phe Leu Ser Gln His
                 260                 265                 270

 Thr Leu Lys Lys Tyr Phe Ile Pro Val Ile Glu Ile Val Pro His
                 275                 280                 285

 Leu Leu Glu Asn Leu Thr Asp Glu Glu Leu Lys Lys Glu Ala Lys
                 290                 295                 300

 Asn Glu Ala Lys Asn Asp Ala Leu Ser Met Ile Ile Lys Ser Leu
                 305                 310                 315

 Lys Asn Leu Ala Ser Arg Ile Ser Gly Gln Asp Glu Thr Ile Lys
                 320                 325                 330

 Asn Leu Glu Ile Phe Arg Leu Lys Met Ile Leu Arg Leu Leu Gln
                 335                 340                 345

 Ile Ser Ser Phe Asn Gly Lys Met Asn Ala Leu Asn Glu Ile Asn
                 350                 355                 360

 Lys Val Ile Ser Ser Val Ser Tyr Tyr Thr His Arg His Ser Asn
                 365                 370                 375

 Pro Glu Glu Glu Glu Trp Leu Thr Ala Glu Arg Met Ala Glu Trp
                 380                 385                 390

 Ile Gln Gln Asn Asn Ile Leu Ser Ile Val Leu Gln Asp Ser Leu
                 395                 400                 405

 His Gln Pro Gln Tyr Val Glu Lys Leu Glu Lys Ile Leu Arg Phe
                 410                 415                 420

 Val Ile Lys Glu Lys Ala Leu Thr Leu Gln Asp Leu Asp Asn Ile
                 425                 430                 435

 Trp Ala Ala Gln Ala Gly Lys His Glu Ala Ile Val Lys Asn Val
                 440                 445                 450

 His Asp Leu Leu Ala Lys Leu Ala Trp Asp Phe Ser Pro Gly Gln
                 455                 460                 465

 Leu Asp His Leu Phe Asp Cys Phe Lys Ala Ser Trp Thr Asn Ala
                 470                 475                 480

 Ser Lys Lys Gln Arg Glu Lys Leu Leu Glu Leu Ile Arg Arg Leu
                 485                 490                 495

 Ala Glu Asp Asp Lys Asp Gly Val Met Ala His Lys Val Leu Asn
                 500                 505                 510

 Leu Leu Trp Asn Leu Ala Gln Ser Asp Asp Val Pro Val Asp Ile
                 515                 520                 525

 Met Asp Leu Ala Leu Ser Ala His Ile Lys Ile Leu Asp Tyr Ser
                 530                 535                 540

 Cys Ser Gln Asp Arg Asp Ala Gln Lys Ile Gln Trp Ile Asp His
                 545                 550                 555

 Phe Ile Glu Glu Leu Arg Thr Asn Asp Lys Trp Val Ile Pro Ala
                 560                 565                 570

 Leu Lys Gln Ile Arg Glu Ile Cys Ser Leu Phe Gly Glu Ala Ser
                 575                 580                 585

 Gln Asn Leu Ser Gln Thr Gln Arg Ser Pro His Ile Phe Tyr Arg
                 590                 595                 600

 His Asp Leu Ile Asn Gln Leu Gln Gln Asn His Ala Leu Val Thr
                 605                 610                 615

 Leu Val Ala Glu Asn Leu Ala Thr Tyr Met Asn Ser Ile Arg Leu
                 620                 625                 630

 Tyr Ala Gly Asp His Glu Asp Tyr Asp Pro Gln Thr Val Arg Leu
                 635                 640                 645

 Gly Ser Arg Tyr Ser His Val Gln Glu Val Gln Glu Arg Leu Asn
                 650                 655                 660

 Phe Leu Arg Phe Leu Leu Lys Asp Gly Gln Leu Trp Leu Cys Ala
                 665                 670                 675

 Pro Gln Ala Lys Gln Ile Trp Lys Cys Leu Ala Glu Asn Ala Val
                 680                 685                 690

 Tyr Leu Cys Asp Arg Glu Ala Cys Phe Lys Trp Tyr Ser Lys Leu
                 695                 700                 705

 Met Gly Asp Glu Pro Asp Leu Asp Pro Asp Ile Asn Lys Asp Phe
                 710                 715                 720

 Phe Glu Ser Asn Val Leu Gln Leu Asp Pro Ser Leu Leu Thr Glu
                 725                 730                 735

 Asn Gly Met Lys Cys Phe Glu Arg Phe Phe Lys Ala Val Asn Cys
                 740                 745                 750

 Arg Glu Arg Lys Leu Ile Ala Lys Arg Arg Ser Tyr Met Met Asp
                 755                 760                 765

 Asp Leu Glu Leu Ile Gly Leu Asp Tyr Leu Trp Arg Val Val Ile
                 770                 775                 780

 Gln Ser Ser Asp Glu Ile Ala Asn Arg Ala Ile Asp Leu Leu Lys
                 785                 790                 795

 Glu Ile Tyr Thr Asn Leu Gly Pro Arg Leu Lys Ala Asn Gln Val
                 800                 805                 810

 Val Ile His Glu Asp Phe Ile Gln Ser Cys Phe Asp Arg Leu Lys
                 815                 820                 825

 Ala Ser Tyr Asp Thr Leu Cys Val Phe Asp Gly Asp Lys Asn Ser
                 830                 835                 840

 Ile Asn Cys Ala Arg Gln Glu Ala Ile Arg Met Val Arg Val Leu
                 845                 850                 855

 Thr Val Ile Lys Glu Tyr Ile Asn Glu Cys Asp Ser Asp Tyr His
                 860                 865                 870

 Lys Glu Arg Met Ile Leu Pro Met Ser Arg Ala Phe Cys Gly Lys
                 875                 880                 885

 His Leu Ser Leu Ile Val Arg Phe Pro Asn Gln Gly Arg Gln Val
                 890                 895                 900

 Asp Glu Leu Asp Ile Trp Phe His Thr Asn Asp Thr Ile Gly Ser
                 905                 910                 915

 Val Arg Arg Cys Ile Val Asn Arg Ile Lys Ala Asn Val Ala His
                 920                 925                 930

 Lys Lys Ile Glu Leu Phe Val Gly Gly Glu Leu Ile Asp Ser Glu
                 935                 940                 945

 Asn Asp Arg Lys Leu Ile Gly Gln Leu Asn Leu Lys Asp Lys Ser
                 950                 955                 960

 Leu Ile Thr Ala Lys Leu Thr Gln Ile Asn Phe Asn Met Pro Ser
                 965                 970                 975

 Ser Pro Asp Ser Ser Ser Asp Ser Ser Thr Ala Ser Pro Gly Asn
                 980                 985                 990

 His Arg Asn His Tyr Asn Asp Gly Pro Asn Leu Lys Val Glu Ser
                 995                1000                1005

 Cys Leu Pro Gly Val Ile Met Ser Val His Pro Lys Tyr Ile Ser
                1010                1015                1020

 Phe Leu Trp Gln Phe Ala Asn Leu Gly Ser Asn Leu Asn Met Pro
                1025                1030                1035

 Pro Leu Lys Asn Gly Ala Arg Val Leu Met Lys Leu Met Pro Pro
                1040                1045                1050

 Asp Arg Thr Ala Val Glu Lys Leu Arg Thr Val Cys Leu Asp His
                1055                1060                1065

 Ala Asn Leu Gly Glu Gly Lys Leu Ser Pro Pro Leu Asp Ser Leu
                1070                1075                1080

 Phe Phe Gly Pro Ser Ala Ser Gln Val Leu Tyr Leu Thr Glu Val
                1085                1090                1095

 Val Tyr Ala Leu Leu Met Pro Ala Gly Val Pro Leu Thr Asp Gly
                1100                1105                1110

 Ser Ser Asp Phe Gln Val His Phe Leu Lys Ser Gly Gly Leu Pro
                1115                1120                1125

 Leu Val Leu Ser Met Leu Ile Arg Asn Asn Phe Leu Pro Asn Thr
                1130                1135                1140

 Asp Met Glu Thr Arg Arg Gly Ala Tyr Leu Asn Ala Leu Lys Ile
                1145                1150                1155

 Ala Lys Leu Leu Leu Thr Ala Ile Gly Tyr Gly His Val Arg Ala
                1160                1165                1170

 Val Ala Glu Ala Cys Gln Pro Val Val Asp Gly Thr Asp Pro Ile
                1175                1180                1185

 Thr Gln Ile Asn Gln Val Thr His Asp Gln Ala Val Val Leu Gln
                1190                1195                1200

 Ser Ala Leu Gln Ser Ile Pro Asn Pro Ser Ser Glu Cys Val Leu
                1205                1210                1215

 Arg Asn Glu Ser Ile Leu Leu Ala Gln Glu Ile Ser Asn Glu Ala
                1220                1225                1230

 Ser Arg Tyr Met Pro Asp Ile Cys Val Ile Arg Ala Ile Gln Lys
                1235                1240                1245

 Ile Ile Trp Ala Ser Ala Cys Gly Ala Leu Gly Leu Phe Phe Ser
                1250                1255                1260

 Pro Asn Glu Glu Ile Thr Lys Ile Tyr Gln Met Thr Thr Asn Gly
                1265                1270                1275

 Ser Asn Lys Leu Glu Val Glu Asp Glu Gln Val Cys Cys Glu Ala
                1280                1285                1290

 Leu Glu Val Met Thr Leu Cys Phe Ala Leu Leu Pro Thr Ala Leu
                1295                1300                1305

 Asp Ala Leu Ser Lys Glu Lys Ala Trp Gln Thr Phe Ile Ile Asp
                1310                1315                1320

 Leu Leu Leu His Cys Pro Ser Lys Thr Val Arg Gln Leu Ala Gln
                1325                1330                1335

 Glu Gln Phe Phe Leu Met Cys Thr Arg Cys Cys Met Gly His Arg
                1340                1345                1350

 Pro Leu Leu Phe Phe Ile Thr Leu Leu Phe Thr Ile Leu Gly Ser
                1355                1360                1365

 Thr Ala Arg Glu Lys Gly Lys Tyr Ser Gly Asp Tyr Phe Thr Leu
                1370                1375                1380

 Leu Arg His Leu Leu Asn Tyr Ala Tyr Asn Gly Asn Ile Asn Ile
                1385                1390                1395

 Pro Asn Ala Glu Val Leu Leu Val Ser Glu Ile Asp Trp Leu Lys
                1400                1405                1410

 Arg Ile Arg Asp Asn Val Lys Asn Thr Gly Glu Thr Gly Val Glu
                1415                1420                1425

 Glu Pro Ile Leu Glu Gly His Leu Gly Val Thr Lys Glu Leu Leu
                1430                1435                1440

 Ala Phe Gln Thr Ser Glu Lys Lys Tyr His Phe Gly Cys Glu Lys
                1445                1450                1455

 Gly Gly Ala Asn Leu Ile Lys Glu Leu Ile Asp Asp Phe Ile Phe
                1460                1465                1470

 Pro Ala Ser Lys Val Tyr Leu Gln Tyr Leu Arg Ser Gly Glu Leu
                1475                1480                1485

 Pro Ala Glu Gln Ala Ile Pro Val Cys Ser Ser Pro Val Thr Ile
                1490                1495                1500

 Asn Ala Gly Phe Glu Leu Leu Val Ala Leu Ala Ile Gly Cys Val
                1505                1510                1515

 Arg Asn Leu Lys Gln Ile Val Asp Cys Leu Thr Glu Met Tyr Tyr
                1520                1525                1530

 Met Gly Thr Ala Ile Thr Thr Cys Glu Ala Leu Thr Glu Trp Glu
                1535                1540                1545

 Tyr Leu Pro Pro Val Gly Pro Arg Pro Pro Lys Gly Phe Val Gly
                1550                1555                1560

 Leu Lys Asn Ala Gly Ala Thr Cys Tyr Met Asn Ser Val Ile Gln
                1565                1570                1575

 Gln Leu Tyr Met Ile Pro Ser Ile Arg Asn Ser Ile Leu Ala Ile
                1580                1585                1590

 Glu Gly Thr Gly Ser Asp Leu His Asp Asp Met Phe Gly Asp Glu
                1595                1600                1605

 Lys Gln Asp Ser Glu Ser Asn Val Asp Pro Arg Asp Asp Val Phe
                1610                1615                1620

 Gly Tyr Pro His Gln Phe Glu Asp Lys Pro Ala Leu Ser Lys Thr
                1625                1630                1635

 Glu Asp Arg Lys Glu Tyr Asn Ile Gly Val Leu Arg His Leu Gln
                1640                1645                1650

 Val Ile Phe Gly His Leu Ala Ala Ser Gln Leu Gln Tyr Tyr Val
                1655                1660                1665

 Pro Arg Gly Phe Trp Lys Gln Phe Arg Leu Trp Gly Glu Pro Val
                1670                1675                1680

 Asn Leu Arg Glu Gln His Asp Ala Leu Glu Phe Phe Asn Ser Leu
                1685                1690                1695

 Val Asp Ser Leu Asp Glu Ala Leu Lys Ala Leu Gly His Pro Ala
                1700                1705                1710

 Ile Leu Ser Lys Val Leu Gly Gly Ser Phe Ala Asp Gln Lys Ile
                1715                1720                1725

 Cys Gln Gly Cys Pro His Arg Phe Glu Cys Glu Glu Ser Phe Thr
                1730                1735                1740

 Thr Leu Asn Val Asp Ile Arg Asn His Gln Asn Leu Leu Asp Ser
                1745                1750                1755

 Leu Glu Gln Tyr Ile Lys Gly Asp Leu Leu Glu Gly Ala Asn Ala
                1760                1765                1770

 Tyr His Cys Glu Lys Cys Asp Lys Lys Val Asp Thr Val Lys Arg
                1775                1780                1785

 Leu Leu Ile Lys Lys Leu Pro Arg Val Leu Ala Ile Gln Leu Lys
                1790                1795                1800

 Arg Phe Asp Tyr Asp Trp Glu Arg Glu Cys Ala Ile Lys Phe Asn
                1805                1810                1815

 Asp Tyr Phe Glu Phe Pro Arg Glu Leu Asp Met Gly Pro Tyr Thr
                1820                1825                1830

 Val Ala Gly Val Ala Asn Leu Glu Arg Asp Asn Val Asn Ser Glu
                1835                1840                1845

 Asn Glu Leu Ile Glu Gln Lys Glu Gln Ser Asp Asn Glu Thr Ala
                1850                1855                1860

 Gly Gly Thr Lys Tyr Arg Leu Val Gly Val Leu Val His Ser Gly
                1865                1870                1875

 Gln Ala Ser Gly Gly His Tyr Tyr Ser Tyr Ile Ile Gln Arg Asn
                1880                1885                1890

 Gly Lys Asp Asp Gln Thr Asp His Trp Tyr Lys Phe Asp Asp Gly
                1895                1900                1905

 Asp Val Thr Glu Cys Lys Met Asp Asp Asp Glu Glu Met Lys Asn
                1910                1915                1920

 Gln Cys Phe Gly Gly Glu Tyr Met Gly Glu Val Phe Asp His Met
                1925                1930                1935

 Met Lys Arg Met Ser Tyr Arg Arg Gln Lys Arg Trp Trp Asn Ala
                1940                1945                1950

 Tyr Ile Pro Phe Tyr Glu Gln Met Asp Met Ile Asp Glu Asp Asp
                1955                1960                1965

 Glu Met Ile Arg Tyr Ile Ser Glu Leu Thr Ile Ala Arg Pro His
                1970                1975                1980

 Gln Ile Ile Met Ser Pro Ala Ile Glu Arg Ser Val Arg Lys Gln
                1985                1990                1995

 Asn Val Lys Phe Met
                2000

<210> 1533
<211> 2372
<212> DNA
<213> Homo sapien

<400> 1533
 gggccgccgt cggcgcgctg ggtgcgggaa gggggctctg gatttcggtc 50

 cctccccttt ttcctctgag tctcggaacg ctccagctct cagaccctct 100

 tcctcccagg taaaggccgg gagaggaggg cgcatctctt ttccaggcac 150

 cccaccatgg gcaatgcctc caatgactcc cagtctgagg actgcgagac 200

 gcgacagtgg cttcccccag gcgaaagccc agccatcagc tccgtcatgt 250

 tctcggccgg ggtgctgggg aacctcatag cactggcgct gctggcgcgc 300

 cgctggcggg gggacgtggg gtgcagcgcc ggccgcagga gctccctctc 350

 cttgttccac gtgctggtga ccgagctggt gttcaccgac ctgctcggga 400

 cctgcctcat cagcccagtg gtactggctt cgtacgcgcg gaaccagacc 450

 ctggtggcac tggcgcccga gagccgcgcg tgcacctact tcgctttcgc 500

 catgaccttc ttcagcctgg ccacgatgct catgctcttc gccatggccc 550

 tggagcgcta cctctcgatc gggcacccct acttctacca gcgccgcgtc 600

 tcggcctccg ggggcctggc cgtgctgcct gtcatctatg cagtctccct 650

 gctcttctgc tcgctgccgc tgctggacta tgggcagtac gtccagtact 700

 gccccgggac ctggtgcttc atccggcacg ggcggaccgc ttacctgcag 750

 ctgtacgcca ccctgctgct gcttctcatt gtctcggtgc tcgcctgcaa 800

 cttcagtgtc attctcaacc tcatccgcat gcaccgccga agccggagaa 850

 gccgctgcgg accttccctg ggcagtggcc ggggcggccc cggggcccgc 900

 aggagagggg aaagggtgtc catggcggag gagacggacc acctcattct 950

 cctggctatc atgaccatca ccttcgccgt ctgctccttg cctttcacga 1000

 tttttgcata tatgaatgaa acctcttccc gaaaggaaaa atgggacctc 1050

 caagctctta ggtttttatc aattaattca ataattgacc cttgggtctt 1100

 tgccatcctt aggcctcctg ttctgagact aatgcgttca gtcctctgtt 1150

 gtcggatttc attaagaaca caagatgcaa cacaaacttc ctgttctaca 1200

 cagtcagatg ccagtaaaca ggctgacctt tgaggtcagt agtttaaaag 1250

 ttcttagtta tatagcatct ggaagatcat tttgaaattg ttccctggag 1300

 aaatgaaaac agtgtgtaaa caaaatgaag ctgccctaat aaaaaggagt 1350

 atacaaacat ttaagctgtg gtcaaggcta cagatgtgct gacaaggcac 1400

 ttcatgtaaa gtgtcagaag gagctacaaa acctaccctc aatgagcatg 1450

 gtacttggcc tttggaggaa caatcggctg cattgaagat ccagctgcct 1500

 attgatttaa gctttcctgt tgaatgacaa agtatgtggt tttgtaattt 1550

 gtttgaaacc ccaaacagtg actgtacttt ctattttaat cttgctacta 1600

 ccgttataca catatagtgt acagccagac cagattaaac ttcatatgta 1650

 atctctagga agtcaatatg tggaagcaac caagcctgct gtcttgtgat 1700

 cacttagcga accctttatt tgaacaatga agttgaaaat cataggcacc 1750

 ttttactgtg atgtttgtgt atgtgggagt actctcatca ctacagtatt 1800

 actcttacaa gagtggactc agtgggttaa catcagtttt gtttactcat 1850

 cctccaggaa ctgcaggtca agttgtcagg ttatttattt tataatgtcc 1900

 atatgctaat agtgatcaag aagactttag gaatggttct ctcaacaaga 1950

 aataatagaa atgtctcaag gcagttaatt ctcattaata ctcttattat 2000

 cctatttctg ggggaggatg tacgtggcca tgtatgaagc caaatattag 2050

 gcttaaaaac tgaaaaatct ggttcattct tcagatatac tggaaccctt 2100

 ttaaagttga tattggggcc atgagtaaaa tagattttat aagatgactg 2150

 tgttgtacca aaattcatct gtctatattt tatttagggg aacatggttt 2200

 gactcatctt atatgggaaa ccatgtagca gtgagtcata tcttaatata 2250

 tttctaaatg tttggcatgt aaatgtaaac tcagcatcaa aatatttcag 2300

 tgaatttgca ctgtttaatc atagttactg tgtaaactca tctgaaatgt 2350

 tacaaaaata aactataaaa ca 2372

<210> 1534
<211> 358
<212> PRT
<213> Homo sapien

<400> 1534
 Met Gly Asn Ala Ser Asn Asp Ser Gln Ser Glu Asp Cys Glu Thr
   1               5                  10                  15

 Arg Gln Trp Leu Pro Pro Gly Glu Ser Pro Ala Ile Ser Ser Val
                  20                  25                  30

 Met Phe Ser Ala Gly Val Leu Gly Asn Leu Ile Ala Leu Ala Leu
                  35                  40                  45

 Leu Ala Arg Arg Trp Arg Gly Asp Val Gly Cys Ser Ala Gly Arg
                  50                  55                  60

 Arg Ser Ser Leu Ser Leu Phe His Val Leu Val Thr Glu Leu Val
                  65                  70                  75

 Phe Thr Asp Leu Leu Gly Thr Cys Leu Ile Ser Pro Val Val Leu
                  80                  85                  90

 Ala Ser Tyr Ala Arg Asn Gln Thr Leu Val Ala Leu Ala Pro Glu
                  95                 100                 105

 Ser Arg Ala Cys Thr Tyr Phe Ala Phe Ala Met Thr Phe Phe Ser
                 110                 115                 120

 Leu Ala Thr Met Leu Met Leu Phe Ala Met Ala Leu Glu Arg Tyr
                 125                 130                 135

 Leu Ser Ile Gly His Pro Tyr Phe Tyr Gln Arg Arg Val Ser Ala
                 140                 145                 150

 Ser Gly Gly Leu Ala Val Leu Pro Val Ile Tyr Ala Val Ser Leu
                 155                 160                 165

 Leu Phe Cys Ser Leu Pro Leu Leu Asp Tyr Gly Gln Tyr Val Gln
                 170                 175                 180

 Tyr Cys Pro Gly Thr Trp Cys Phe Ile Arg His Gly Arg Thr Ala
                 185                 190                 195

 Tyr Leu Gln Leu Tyr Ala Thr Leu Leu Leu Leu Leu Ile Val Ser
                 200                 205                 210

 Val Leu Ala Cys Asn Phe Ser Val Ile Leu Asn Leu Ile Arg Met
                 215                 220                 225

 His Arg Arg Ser Arg Arg Ser Arg Cys Gly Pro Ser Leu Gly Ser
                 230                 235                 240

 Gly Arg Gly Gly Pro Gly Ala Arg Arg Arg Gly Glu Arg Val Ser
                 245                 250                 255

 Met Ala Glu Glu Thr Asp His Leu Ile Leu Leu Ala Ile Met Thr
                 260                 265                 270

 Ile Thr Phe Ala Val Cys Ser Leu Pro Phe Thr Ile Phe Ala Tyr
                 275                 280                 285

 Met Asn Glu Thr Ser Ser Arg Lys Glu Lys Trp Asp Leu Gln Ala
                 290                 295                 300

 Leu Arg Phe Leu Ser Ile Asn Ser Ile Ile Asp Pro Trp Val Phe
                 305                 310                 315

 Ala Ile Leu Arg Pro Pro Val Leu Arg Leu Met Arg Ser Val Leu
                 320                 325                 330

 Cys Cys Arg Ile Ser Leu Arg Thr Gln Asp Ala Thr Gln Thr Ser
                 335                 340                 345

 Cys Ser Thr Gln Ser Asp Ala Ser Lys Gln Ala Asp Leu
                 350                 355

<210> 1535
<211> 1536
<212> DNA
<213> Homo sapien

<400> 1535
 acagagcttc aaaaaaagag cgggacaggg acaagcgtat ctaagaggct 50

 gaacatgaat ccacagatca gaaatccgat ggagcggatg tatcgagaca 100

 cattctacga caactttgaa aacgaaccca tcctctatgg tcggagctac 150

 acttggctgt gctatgaagt gaaaataaag aggggccgct caaatctcct 200

 ttgggacaca ggggtctttc gaggccaggt gtatttcaag cctcagtacc 250

 acgcagaaat gtgcttcctc tcttggttct gtggcaacca gctgcctgct 300

 tacaagtgtt tccagatcac ctggtttgta tcctggaccc cctgcccgga 350

 ctgtgtggcg aagctggccg aattcctgtc tgagcacccc aatgtcaccc 400

 tgaccatctc tgccgcccgc ctctactact actgggaaag agattaccga 450

 agggcgctct gcaggctgag tcaggcagga gcccgcgtga cgatcatgga 500

 ctatgaagaa tttgcatact gctgggaaaa ctttgtgtac aatgaaggtc 550

 agcaattcat gccttggtac aaattcgatg aaaattatgc attcctgcac 600

 cgcacgctaa aggagattct cagatacctg atggatccag acacattcac 650

 tttcaacttt aataatgacc ctttggtcct tcgacggcgc cagacctact 700

 tgtgctatga ggtggagcgc ctggacaatg gcacctgggt cctgatggac 750

 cagcacatgg gctttctatg caacgaggct aagaatcttc tctgtggctt 800

 ttacggccgc catgcggagc tgcgcttctt ggacctggtt ccttctttgc 850

 agttggaccc ggcccagatc tacagggtca cttggttcat ctcctggagc 900

 ccctgcttct cctggggctg tgccggggaa gtgcgtgcgt tccttcagga 950

 gaacacacac gtgagactgc gcatcttcgc tgcccgcatc tatgattacg 1000

 accccctata taaggaggcg ctgcaaatgc tgcgggatgc tggggcccaa 1050

 gtctccatca tgacctacga tgagtttgag tactgctggg acacctttgt 1100

 gtaccgccag ggatgtccct tccagccctg ggatggacta gaggagcaca 1150

 gccaagccct gagtgggagg ctgcgggcca ttctccagaa tcagggaaac 1200

 tgaaggatgg gcctcagtct ctaaggaagg cagagacctg ggttgagcag 1250

 cagaataaaa gatcttcttc caagaaatgc aaacagaccg ttcaccacca 1300

 tctccagctg ctcacagaca ccagcaaagc aatgtgctcc tgatcaagta 1350

 gattttttaa aaatcagagt caattaattt taattgaaaa tttctcttat 1400

 gttccaagtg tacaagagta agattatgct caatattccc agaatagttt 1450

 tcaatgtatt aatgaagtga ttaattggct ccatatttag actaataaaa 1500

 cattaagaat cttccataat tgtttccaca aacact 1536

<210> 1536
<211> 382
<212> PRT
<213> Homo sapien

<400> 1536
 Met Asn Pro Gln Ile Arg Asn Pro Met Glu Arg Met Tyr Arg Asp
   1               5                  10                  15

 Thr Phe Tyr Asp Asn Phe Glu Asn Glu Pro Ile Leu Tyr Gly Arg
                  20                  25                  30

 Ser Tyr Thr Trp Leu Cys Tyr Glu Val Lys Ile Lys Arg Gly Arg
                  35                  40                  45

 Ser Asn Leu Leu Trp Asp Thr Gly Val Phe Arg Gly Gln Val Tyr
                  50                  55                  60

 Phe Lys Pro Gln Tyr His Ala Glu Met Cys Phe Leu Ser Trp Phe
                  65                  70                  75

 Cys Gly Asn Gln Leu Pro Ala Tyr Lys Cys Phe Gln Ile Thr Trp
                  80                  85                  90

 Phe Val Ser Trp Thr Pro Cys Pro Asp Cys Val Ala Lys Leu Ala
                  95                 100                 105

 Glu Phe Leu Ser Glu His Pro Asn Val Thr Leu Thr Ile Ser Ala
                 110                 115                 120

 Ala Arg Leu Tyr Tyr Tyr Trp Glu Arg Asp Tyr Arg Arg Ala Leu
                 125                 130                 135

 Cys Arg Leu Ser Gln Ala Gly Ala Arg Val Thr Ile Met Asp Tyr
                 140                 145                 150

 Glu Glu Phe Ala Tyr Cys Trp Glu Asn Phe Val Tyr Asn Glu Gly
                 155                 160                 165

 Gln Gln Phe Met Pro Trp Tyr Lys Phe Asp Glu Asn Tyr Ala Phe
                 170                 175                 180

 Leu His Arg Thr Leu Lys Glu Ile Leu Arg Tyr Leu Met Asp Pro
                 185                 190                 195

 Asp Thr Phe Thr Phe Asn Phe Asn Asn Asp Pro Leu Val Leu Arg
                 200                 205                 210

 Arg Arg Gln Thr Tyr Leu Cys Tyr Glu Val Glu Arg Leu Asp Asn
                 215                 220                 225

 Gly Thr Trp Val Leu Met Asp Gln His Met Gly Phe Leu Cys Asn
                 230                 235                 240

 Glu Ala Lys Asn Leu Leu Cys Gly Phe Tyr Gly Arg His Ala Glu
                 245                 250                 255

 Leu Arg Phe Leu Asp Leu Val Pro Ser Leu Gln Leu Asp Pro Ala
                 260                 265                 270

 Gln Ile Tyr Arg Val Thr Trp Phe Ile Ser Trp Ser Pro Cys Phe
                 275                 280                 285

 Ser Trp Gly Cys Ala Gly Glu Val Arg Ala Phe Leu Gln Glu Asn
                 290                 295                 300

 Thr His Val Arg Leu Arg Ile Phe Ala Ala Arg Ile Tyr Asp Tyr
                 305                 310                 315

 Asp Pro Leu Tyr Lys Glu Ala Leu Gln Met Leu Arg Asp Ala Gly
                 320                 325                 330

 Ala Gln Val Ser Ile Met Thr Tyr Asp Glu Phe Glu Tyr Cys Trp
                 335                 340                 345

 Asp Thr Phe Val Tyr Arg Gln Gly Cys Pro Phe Gln Pro Trp Asp
                 350                 355                 360

 Gly Leu Glu Glu His Ser Gln Ala Leu Ser Gly Arg Leu Arg Ala
                 365                 370                 375

 Ile Leu Gln Asn Gln Gly Asn
                 380

<210> 1537
<211> 2088
<212> DNA
<213> Homo sapien

<400> 1537
 cttaactcct gatcttttgt aaaactattg ctagtcataa tggatttcta 50

 taacctgaaa gttgatataa tacagcacgt ggagcacttt aaaaacaaag 100

 aaacttgaaa ataattttat tttttacctt tacatggtgt gttctagact 150

 actgcattat gactacataa acctacctga gctcttacaa gtacagaatt 200

 gtgagacaga ggttttgtga tggaaaacat acacataggg aaaaatacca 250

 aactgagcaa tataaatttc acagctcaca tcttagccag tacaaagaaa 300

 ctttcacatg gggtgaatat tataatactt gaatttgaga cttaatactg 350

 tatatgaatt aatcatccca ctgtaataac tgacatcttc aaatagttgg 400

 gcttatgaaa aatttgacta agacatttta ttttatactt tatgtaaatg 450

 tgaaataagt tctggtcata taaatatgta gaatgcatgt gtgtgaactc 500

 tatgaagtga agtgtggtgg ccttttatgt ttcagagtac tcaagtgtac 550

 aattgattta tataaaaatg caaaatgaac tcaggtcatt ttgaaattaa 600

 tattaatatt tttgttgttt aactttaaag ctagctcccc taactttata 650

 tattttttgg gaaaaaatac ctaaaaacct cagcctacaa agactctcag 700

 aaatgccaaa gattttcaag gaaattcata ttatatattt caaaaatgat 750

 ttatcaatgt tatctaccaa aagaaataat tttatttttc ccctttgggg 800

 agatattatc ctctaatatg agaatcagat ccctagattc tatttctacc 850

 tatactatta aactcaacct tgaacctgag cttggttgtt tctgtgcctt 900

 agtttctcca ctcgtaaaca atttcctata aaaattgttt aaacaccaac 950

 caaaatttac catatgtatt cattctcttg ccttaaagat cacttcttaa 1000

 cttacatttg gctctcaccc tctaaaaatt tgtagtttgg agagtaactg 1050

 aaagcacaat tttaagaaac atgttttcct cacaaaatat attgtaatct 1100

 gattttccta tcttgtattc atgcagaaaa ttggagaaaa tgtgtattgt 1150

 cttgtgccat tctgcaatat gaatttctca ggaaaaagat gtttcaatgg 1200

 caatactttc ttaaataatt caagatgggt gtgaggacct atcttattag 1250

 tttagtgctg tgttaaccat ttgtgaatta cttcttgttt aaaggaagtt 1300

 gtcaaaaaat tttaagattc taaatggaat acacgaataa agtaagcctt 1350

 agaatagaaa cctcacaaaa agttgtcatt tgcggttgat aattaacata 1400

 ggtgttttat tctctcaact ccttagtacc agagccaaat acaatttagt 1450

 tttcagaaat cttatcaata ttgttctatt tacctactta taaatctgca 1500

 gataaccact tgaaccaggc aaatacactg aagataaagg ttatttcttt 1550

 ttttagcttt gaatttgtca tgaccatttt agtcttgcag atagcagggc 1600

 agccccttgg ggcaaggatt tactctggga ggtaccgtta agagccttct 1650

 ttcccccttt gaaagatcct tttacaatgt taaagtatac tagttgcaag 1700

 aacaagcagg atttgcaggt tgctttacca gcatgagtct catttttctg 1750

 gcttaaaatc tgggactgtg aaattattcc ataggaaagt gaatgttatt 1800

 ttgcagaatt agcctcttac ataaaagtat ttgttgaagt gtctttaaaa 1850

 ttgctatcat gagcaaaact ggttgctgta atgcttgttt ttctgtattt 1900

 atttacacat taaattctta caaaacaaaa tgtgttcgtt tgttttatag 1950

 taagatgttt tattttgaac ttatttaaat gtttatttgt tagagaaaac 2000

 taatttgtta atatagatct taactagtaa ctattaagca gggatgtttg 2050

 ttccaaatat tcttgaataa acaatcacca caaacaac 2088

<210> 1538
<211> 61
<212> PRT
<213> Homo sapien

<400> 1538
 Met Ile Tyr Gln Cys Tyr Leu Pro Lys Glu Ile Ile Leu Phe Phe
   1               5                  10                  15

 Pro Phe Gly Glu Ile Leu Ser Ser Asn Met Arg Ile Arg Ser Leu
                  20                  25                  30

 Asp Ser Ile Ser Thr Tyr Thr Ile Lys Leu Asn Leu Glu Pro Glu
                  35                  40                  45

 Leu Gly Cys Phe Cys Ala Leu Val Ser Pro Leu Val Asn Asn Phe
                  50                  55                  60

 Leu


<210> 1539
<211> 1040
<212> DNA
<213> Homo sapien

<400> 1539
 aacacatttc atctgggctt cttaaatcta aatctttaaa atgactaagt 50

 tttcttcctt ttctctgttt ttcctaatag ttggggctta tatgactcat 100

 gtgtgtttca atatggaaat tattggaggg aaagaagtgt cacctcattc 150

 caggccattt atggcctcca tccagtatgg cggacatcac gtttgtggag 200

 gtgttctgat tgatccacag tgggtgctga cagcagccca ctgccaatat 250

 cggtttacca aaggccagtc tcccactgtg gttttaggcg cacactctct 300

 ctcaaagaat gaggcctcca aacaaacact ggagatcaaa aaatttatac 350

 cattctcaag agttacatca gatcctcaat caaatgatat catgctggtt 400

 aagcttcaaa cagccgcaaa actcaataaa catgtcaaga tgctccacat 450

 aagatccaaa acctctctta gatctggaac caaatgcaag gttactggct 500

 ggggagccac cgatccagat tcattaagac cttctgacac cctgcgagaa 550

 gtcactgtta ctgtcctaag tcgaaaactt tgcaacagcc aaagttacta 600

 caacggcgac ccttttatca ccaaagacat ggtctgtgca ggagatgcca 650

 aaggccagaa ggattcctgt aagggtgact cagggggccc cttgatctgt 700

 aaaggtgtct tccacgctat agtctctgga ggtcatgaat gtggtgttgc 750

 cacaaagcct ggaatctaca ccctgttaac caagaaatac cagacttgga 800

 tcaaaagcaa ccttgtcccg cctcatacaa attaagttac aaataatttt 850

 attggatgca cttgcttctt ttttcctaat atgctcgcag gttagagttg 900

 ggtgtaagta aagcagagca catatggggt ccatttttgc acttgtaagt 950

 cattttatta aggaatcaag ttctttttca cttgtatcac tgatgtattt 1000

 ctaccatgct ggttttattc taaataaaat ttagaagact 1040

<210> 1540
<211> 264
<212> PRT
<213> Homo sapien

<400> 1540
 Met Thr Lys Phe Ser Ser Phe Ser Leu Phe Phe Leu Ile Val Gly
   1               5                  10                  15

 Ala Tyr Met Thr His Val Cys Phe Asn Met Glu Ile Ile Gly Gly
                  20                  25                  30

 Lys Glu Val Ser Pro His Ser Arg Pro Phe Met Ala Ser Ile Gln
                  35                  40                  45

 Tyr Gly Gly His His Val Cys Gly Gly Val Leu Ile Asp Pro Gln
                  50                  55                  60

 Trp Val Leu Thr Ala Ala His Cys Gln Tyr Arg Phe Thr Lys Gly
                  65                  70                  75

 Gln Ser Pro Thr Val Val Leu Gly Ala His Ser Leu Ser Lys Asn
                  80                  85                  90

 Glu Ala Ser Lys Gln Thr Leu Glu Ile Lys Lys Phe Ile Pro Phe
                  95                 100                 105

 Ser Arg Val Thr Ser Asp Pro Gln Ser Asn Asp Ile Met Leu Val
                 110                 115                 120

 Lys Leu Gln Thr Ala Ala Lys Leu Asn Lys His Val Lys Met Leu
                 125                 130                 135

 His Ile Arg Ser Lys Thr Ser Leu Arg Ser Gly Thr Lys Cys Lys
                 140                 145                 150

 Val Thr Gly Trp Gly Ala Thr Asp Pro Asp Ser Leu Arg Pro Ser
                 155                 160                 165

 Asp Thr Leu Arg Glu Val Thr Val Thr Val Leu Ser Arg Lys Leu
                 170                 175                 180

 Cys Asn Ser Gln Ser Tyr Tyr Asn Gly Asp Pro Phe Ile Thr Lys
                 185                 190                 195

 Asp Met Val Cys Ala Gly Asp Ala Lys Gly Gln Lys Asp Ser Cys
                 200                 205                 210

 Lys Gly Asp Ser Gly Gly Pro Leu Ile Cys Lys Gly Val Phe His
                 215                 220                 225

 Ala Ile Val Ser Gly Gly His Glu Cys Gly Val Ala Thr Lys Pro
                 230                 235                 240

 Gly Ile Tyr Thr Leu Leu Thr Lys Lys Tyr Gln Thr Trp Ile Lys
                 245                 250                 255

 Ser Asn Leu Val Pro Pro His Thr Asn
                 260

<210> 1541
<211> 2304
<212> DNA
<213> Homo sapien

<400> 1541
 agtggagtgg cagccccaga actgggacca ccgggggtgg tgaggcggcc 50

 cggcactggg agctgcatct gaggcttagt ccctgagctc tctgcctgcc 100

 cagactagct gcacctcctc attccctgcg cccccttcct ctccggaagc 150

 ccccaggatg gtgaggtggt ttcaccgaga cctcagtggg ctggatgcag 200

 agaccctgct caagggccga ggtgtccacg gtagcttcct ggctcggccc 250

 agtcgcaaga accagggtga cttctcgctc tccgtcaggg tgggggatca 300

 ggtgacccat attcggatcc agaactcagg ggatttctat gacctgtatg 350

 gaggggagaa gtttgcgact ctgacagagc tggtggagta ctacactcag 400

 cagcagggtg tcctgcagga ccgcgacggc accatcatcc acctcaagta 450

 cccgctgaac tgctccgatc ccactagtga gaggtggtac catggccaca 500

 tgtctggcgg gcaggcagag acgctgctgc aggccaaggg cgagccctgg 550

 acgtttcttg tgcgtgagag cctcagccag cctggagact tcgtgctttc 600

 tgtgctcagt gaccagccca aggctggccc aggctccccg ctcagggtca 650

 cccacatcaa ggtcatgtgc gagggtggac gctacacagt gggtggtttg 700

 gagaccttcg acagcctcac ggacctggtg gagcatttca agaagacggg 750

 gattgaggag gcctcaggcg cctttgtcta cctgcggcag ccgtactatg 800

 ccacgagggt gaatgcggct gacattgaga accgagtgtt ggaactgaac 850

 aagaagcagg agtccgagga tacagccaag gctggcttct gggaggagtt 900

 tgagagtttg cagaagcagg aggtgaagaa cttgcaccag cgtctggaag 950

 ggcagcggcc agagaacaag ggcaagaacc gctacaagaa cattctcccc 1000

 tttgaccaca gccgagtgat cctgcaggga cgggacagta acatccccgg 1050

 gtccgactac atcaatgcca actacatcaa gaaccagctg ctaggccctg 1100

 atgagaacgc taagacctac atcgccagcc agggctgtct ggaggccacg 1150

 gtcaatgact tctggcagat ggcgtggcag gagaacagcc gtgtcatcgt 1200

 catgaccacc cgagaggtgg agaaaggccg gaacaaatgc gtcccatact 1250

 ggcccgaggt gggcatgcag cgtgcttatg ggccctactc tgtgaccaac 1300

 tgcggggagc atgacacaac cgaatacaaa ctccgtacct tacaggtctc 1350

 cccgctggac aatggagacc tgattcggga gatctggcat taccagtacc 1400

 tgagctggcc cgaccatggg gtccccagtg agcctggggg tgtcctcagc 1450

 ttcctggacc agatcaacca gcggcaggaa agtctgcctc acgcagggcc 1500

 catcatcgtg cactgcagcg ccggcatcgg ccgcacaggc accatcattg 1550

 tcatcgacat gctcatggag aacatctcca ccaagggcct ggactgtgac 1600

 attgacatcc agaagaccat ccagatggtg cgggcgcagc gctcgggcat 1650

 ggtgcagacg gaggcgcagt acaagttcat ctacgtggcc atcgcccagt 1700

 tcattgaaac cactaagaag aagctggagg tcctgcagtc gcagaagggc 1750

 caggagtcgg agtacgggaa catcacctat cccccagcca tgaagaatgc 1800

 ccatgccaag gcctcccgca cctcgtccaa gagcttggag tctagtgcag 1850

 ggaccgtggc tgcgtcacct gtgagacggg gtggccagag gggactgcca 1900

 gtgccgggtc cccctgtgct gtctcctgac ctgcaccaac tgcctgtact 1950

 tgcccccctg cacccggctg cagacacaag gaggatgtgt atgagaacct 2000

 gcacactaag aacaagaggg aggagaaagt gaagaagcag cggtcagcag 2050

 acaaggagaa gagcaagggt tccctcaaga ggaagtgagc ggtgctgtcc 2100

 tcaggtggcc atgcctcagc cctgaccctg tggaagcatt tcgcgatgga 2150

 cagactcaca acctgaacct aggagtgccc cattcttttg taatttaaat 2200

 ggctgcatcc cccccacctc tccctgaccc tgtatatagc ccagccaggc 2250

 cccaggcagg gccaaccctt ctcctcttgt aaataaagcc ctgggatcac 2300

 tgtg 2304

<210> 1542
<211> 624
<212> PRT
<213> Homo sapien

<400> 1542
 Met Val Arg Trp Phe His Arg Asp Leu Ser Gly Leu Asp Ala Glu
   1               5                  10                  15

 Thr Leu Leu Lys Gly Arg Gly Val His Gly Ser Phe Leu Ala Arg
                  20                  25                  30

 Pro Ser Arg Lys Asn Gln Gly Asp Phe Ser Leu Ser Val Arg Val
                  35                  40                  45

 Gly Asp Gln Val Thr His Ile Arg Ile Gln Asn Ser Gly Asp Phe
                  50                  55                  60

 Tyr Asp Leu Tyr Gly Gly Glu Lys Phe Ala Thr Leu Thr Glu Leu
                  65                  70                  75

 Val Glu Tyr Tyr Thr Gln Gln Gln Gly Val Leu Gln Asp Arg Asp
                  80                  85                  90

 Gly Thr Ile Ile His Leu Lys Tyr Pro Leu Asn Cys Ser Asp Pro
                  95                 100                 105

 Thr Ser Glu Arg Trp Tyr His Gly His Met Ser Gly Gly Gln Ala
                 110                 115                 120

 Glu Thr Leu Leu Gln Ala Lys Gly Glu Pro Trp Thr Phe Leu Val
                 125                 130                 135

 Arg Glu Ser Leu Ser Gln Pro Gly Asp Phe Val Leu Ser Val Leu
                 140                 145                 150

 Ser Asp Gln Pro Lys Ala Gly Pro Gly Ser Pro Leu Arg Val Thr
                 155                 160                 165

 His Ile Lys Val Met Cys Glu Gly Gly Arg Tyr Thr Val Gly Gly
                 170                 175                 180

 Leu Glu Thr Phe Asp Ser Leu Thr Asp Leu Val Glu His Phe Lys
                 185                 190                 195

 Lys Thr Gly Ile Glu Glu Ala Ser Gly Ala Phe Val Tyr Leu Arg
                 200                 205                 210

 Gln Pro Tyr Tyr Ala Thr Arg Val Asn Ala Ala Asp Ile Glu Asn
                 215                 220                 225

 Arg Val Leu Glu Leu Asn Lys Lys Gln Glu Ser Glu Asp Thr Ala
                 230                 235                 240

 Lys Ala Gly Phe Trp Glu Glu Phe Glu Ser Leu Gln Lys Gln Glu
                 245                 250                 255

 Val Lys Asn Leu His Gln Arg Leu Glu Gly Gln Arg Pro Glu Asn
                 260                 265                 270

 Lys Gly Lys Asn Arg Tyr Lys Asn Ile Leu Pro Phe Asp His Ser
                 275                 280                 285

 Arg Val Ile Leu Gln Gly Arg Asp Ser Asn Ile Pro Gly Ser Asp
                 290                 295                 300

 Tyr Ile Asn Ala Asn Tyr Ile Lys Asn Gln Leu Leu Gly Pro Asp
                 305                 310                 315

 Glu Asn Ala Lys Thr Tyr Ile Ala Ser Gln Gly Cys Leu Glu Ala
                 320                 325                 330

 Thr Val Asn Asp Phe Trp Gln Met Ala Trp Gln Glu Asn Ser Arg
                 335                 340                 345

 Val Ile Val Met Thr Thr Arg Glu Val Glu Lys Gly Arg Asn Lys
                 350                 355                 360

 Cys Val Pro Tyr Trp Pro Glu Val Gly Met Gln Arg Ala Tyr Gly
                 365                 370                 375

 Pro Tyr Ser Val Thr Asn Cys Gly Glu His Asp Thr Thr Glu Tyr
                 380                 385                 390

 Lys Leu Arg Thr Leu Gln Val Ser Pro Leu Asp Asn Gly Asp Leu
                 395                 400                 405

 Ile Arg Glu Ile Trp His Tyr Gln Tyr Leu Ser Trp Pro Asp His
                 410                 415                 420

 Gly Val Pro Ser Glu Pro Gly Gly Val Leu Ser Phe Leu Asp Gln
                 425                 430                 435

 Ile Asn Gln Arg Gln Glu Ser Leu Pro His Ala Gly Pro Ile Ile
                 440                 445                 450

 Val His Cys Ser Ala Gly Ile Gly Arg Thr Gly Thr Ile Ile Val
                 455                 460                 465

 Ile Asp Met Leu Met Glu Asn Ile Ser Thr Lys Gly Leu Asp Cys
                 470                 475                 480

 Asp Ile Asp Ile Gln Lys Thr Ile Gln Met Val Arg Ala Gln Arg
                 485                 490                 495

 Ser Gly Met Val Gln Thr Glu Ala Gln Tyr Lys Phe Ile Tyr Val
                 500                 505                 510

 Ala Ile Ala Gln Phe Ile Glu Thr Thr Lys Lys Lys Leu Glu Val
                 515                 520                 525

 Leu Gln Ser Gln Lys Gly Gln Glu Ser Glu Tyr Gly Asn Ile Thr
                 530                 535                 540

 Tyr Pro Pro Ala Met Lys Asn Ala His Ala Lys Ala Ser Arg Thr
                 545                 550                 555

 Ser Ser Lys Ser Leu Glu Ser Ser Ala Gly Thr Val Ala Ala Ser
                 560                 565                 570

 Pro Val Arg Arg Gly Gly Gln Arg Gly Leu Pro Val Pro Gly Pro
                 575                 580                 585

 Pro Val Leu Ser Pro Asp Leu His Gln Leu Pro Val Leu Ala Pro
                 590                 595                 600

 Leu His Pro Ala Ala Asp Thr Arg Arg Met Cys Met Arg Thr Cys
                 605                 610                 615

 Thr Leu Arg Thr Arg Gly Arg Arg Lys
                 620

<210> 1543
<211> 2452
<212> DNA
<213> Homo sapien

<400> 1543
 cgcaagaatg catacaaact ccagggctgc tctctcctgg agagggaggg 50

 aggggattta aaaacctgca gcaacatggg ggaggaggct gtttgtcctt 100

 ctctctctgg ggaagtaact cgctcaaact gccttccttg ctgagctgct 150

 tcgcgtagct ttgaggaagg tctagtgaaa ttggtctttc cattacatct 200

 ggatgtacta ccagagagtt ctgctgctgt tgtttttttt agcttttctt 250

 tctttgagtc tttaaagggc aattgtcgac actctgcaaa cataccgatt 300

 tgttgtctgc ccactttgga gtcttcaatc tgggcagtaa ctatttaccc 350

 tttttcctgc tagcctgtcc ccctctctgg attgaagtca cctgctaaga 400

 caatggacta ccgaccagac tcccggaaat catgttggta ggatcccagt 450

 ctttttcgcc tggagggccc aatgggatca ttagaagcca gtcctttgcg 500

 ggtttcagcg gcctccagga aaggcgatcc aggtgtaact ccttcattga 550

 aaattcctcc gctctcaaga agcctcaggc caaactgaag aaaatgcaca 600

 atttaggcca caaaaacaac aatcccccca aagagcctca gcctaaaagg 650

 gtggaagaag tctacagggc cttgaaaaat ggacttgatg aatatctgga 700

 ggttcaccag acggagctgg acaagttgac agctcagtta aaagatatga 750

 aaagaaactc tcgcctgggt gtactgtatg acctagacaa gcaaattaaa 800

 acaattgaaa gatacatgag acgcctggag tttcatataa gtaaggtaga 850

 tgaactctat gaagcttatt gtatccagcg acgcctccag gatggtgcca 900

 gcaaaatgaa gcaagccttc gcaacatccc ctgccagcaa agctgcccgg 950

 gagagtctga cagagatcaa tcggagcttc aaggagtaca cagagaatat 1000

 gtgcaccatt gaagtggagc tagagaatct gctgggagaa ttctccatca 1050

 agatgaaagg tctggctggc tttgcacgcc tctgtcctgg agatcaatat 1100

 gaaattttca tgaagtatgg ccggcagcgg tggaaactga aaggcaaaat 1150

 agaagtaaat ggcaagcaga gctgggatgg agaagaaaca gtttttctgc 1200

 ccctgatagt tgggttcatc tccatcaagg tcacggagct caaagggcta 1250

 gcaactcaca tcctggtagg tagcgtgacc tgtgagacca aagagctgtt 1300

 tgcagcccga cctcaggtag tggctgtcga catcaatgac cttggtacca 1350

 tcaaactgaa cctggaaatc acctggtatc catttgacgt ggaggacatg 1400

 accgcatcct caggcgctgg gaacaaggca gcagcccttc agaggagaat 1450

 gtccatgtac agccagggta ccccggaaac gcccaccttc aaagaccact 1500

 ccttcttttc aaatctacct gatgacatct ttgaaaatgg aaaggcagcc 1550

 gaggagaaaa tgccactgtc gctcagcttc agtgacctgc ccaacgggga 1600

 ctgcgccctc acctcccact caacaggctc cccttccaac tcaacaaatc 1650

 cagaaattac catcacccct gcggagttta acctcagcag cttggcctcc 1700

 cagaatgagg gtatggatga caccagctca gcatcttcca ggaactccct 1750

 gggagaaggc caagagccaa agtcacacct gaaggaggaa gacccagagg 1800

 agcccagaaa acctgcctcg gccccatctg aggcttgccg ccgacagtcc 1850

 tcaggtgctg gggctgagca cctgttcctt gagaatgatg ttgcagaagc 1900

 acttctgcaa gagtctgagg aggcctctga gctcaagcct gtggaactgg 1950

 acacttcgga aggaaacatc acaaagcagc tggtcaagag gctcacatct 2000

 gcagaggtgc caatggccac agacaggctg ctctctgagg gttctgttgg 2050

 tggagaatct gaaggctgca gatcctttct agatggaagc ttagaggatg 2100

 cttttaatgg gcttttactt gcattagaac cacataaaga gcagtataaa 2150

 gagtttcagg atctgaacca agaagtcatg aatttggatg atattctaaa 2200

 aaagtagaga agatcctcta atggatccca gtgtgcccat ccctcaacct 2250

 cctcagtgat caactcatgg ccaatcttgt ttcctattct tcaacctgct 2300

 gacttccctc tggattcttc tgcaaccagt cccagatatt gtgccatttt 2350

 atccatggtt gtacttcttt tttggatata aagattttta aatgcatttt 2400

 ttaaatgcta acaaaaaata aaaacttgaa acaaaaaaaa aaaaaaaaaa 2450

 aa 2452

<210> 1544
<211> 591
<212> PRT
<213> Homo sapien

<400> 1544
 Met Leu Val Gly Ser Gln Ser Phe Ser Pro Gly Gly Pro Asn Gly
   1               5                  10                  15

 Ile Ile Arg Ser Gln Ser Phe Ala Gly Phe Ser Gly Leu Gln Glu
                  20                  25                  30

 Arg Arg Ser Arg Cys Asn Ser Phe Ile Glu Asn Ser Ser Ala Leu
                  35                  40                  45

 Lys Lys Pro Gln Ala Lys Leu Lys Lys Met His Asn Leu Gly His
                  50                  55                  60

 Lys Asn Asn Asn Pro Pro Lys Glu Pro Gln Pro Lys Arg Val Glu
                  65                  70                  75

 Glu Val Tyr Arg Ala Leu Lys Asn Gly Leu Asp Glu Tyr Leu Glu
                  80                  85                  90

 Val His Gln Thr Glu Leu Asp Lys Leu Thr Ala Gln Leu Lys Asp
                  95                 100                 105

 Met Lys Arg Asn Ser Arg Leu Gly Val Leu Tyr Asp Leu Asp Lys
                 110                 115                 120

 Gln Ile Lys Thr Ile Glu Arg Tyr Met Arg Arg Leu Glu Phe His
                 125                 130                 135

 Ile Ser Lys Val Asp Glu Leu Tyr Glu Ala Tyr Cys Ile Gln Arg
                 140                 145                 150

 Arg Leu Gln Asp Gly Ala Ser Lys Met Lys Gln Ala Phe Ala Thr
                 155                 160                 165

 Ser Pro Ala Ser Lys Ala Ala Arg Glu Ser Leu Thr Glu Ile Asn
                 170                 175                 180

 Arg Ser Phe Lys Glu Tyr Thr Glu Asn Met Cys Thr Ile Glu Val
                 185                 190                 195

 Glu Leu Glu Asn Leu Leu Gly Glu Phe Ser Ile Lys Met Lys Gly
                 200                 205                 210

 Leu Ala Gly Phe Ala Arg Leu Cys Pro Gly Asp Gln Tyr Glu Ile
                 215                 220                 225

 Phe Met Lys Tyr Gly Arg Gln Arg Trp Lys Leu Lys Gly Lys Ile
                 230                 235                 240

 Glu Val Asn Gly Lys Gln Ser Trp Asp Gly Glu Glu Thr Val Phe
                 245                 250                 255

 Leu Pro Leu Ile Val Gly Phe Ile Ser Ile Lys Val Thr Glu Leu
                 260                 265                 270

 Lys Gly Leu Ala Thr His Ile Leu Val Gly Ser Val Thr Cys Glu
                 275                 280                 285

 Thr Lys Glu Leu Phe Ala Ala Arg Pro Gln Val Val Ala Val Asp
                 290                 295                 300

 Ile Asn Asp Leu Gly Thr Ile Lys Leu Asn Leu Glu Ile Thr Trp
                 305                 310                 315

 Tyr Pro Phe Asp Val Glu Asp Met Thr Ala Ser Ser Gly Ala Gly
                 320                 325                 330

 Asn Lys Ala Ala Ala Leu Gln Arg Arg Met Ser Met Tyr Ser Gln
                 335                 340                 345

 Gly Thr Pro Glu Thr Pro Thr Phe Lys Asp His Ser Phe Phe Ser
                 350                 355                 360

 Asn Leu Pro Asp Asp Ile Phe Glu Asn Gly Lys Ala Ala Glu Glu
                 365                 370                 375

 Lys Met Pro Leu Ser Leu Ser Phe Ser Asp Leu Pro Asn Gly Asp
                 380                 385                 390

 Cys Ala Leu Thr Ser His Ser Thr Gly Ser Pro Ser Asn Ser Thr
                 395                 400                 405

 Asn Pro Glu Ile Thr Ile Thr Pro Ala Glu Phe Asn Leu Ser Ser
                 410                 415                 420

 Leu Ala Ser Gln Asn Glu Gly Met Asp Asp Thr Ser Ser Ala Ser
                 425                 430                 435

 Ser Arg Asn Ser Leu Gly Glu Gly Gln Glu Pro Lys Ser His Leu
                 440                 445                 450

 Lys Glu Glu Asp Pro Glu Glu Pro Arg Lys Pro Ala Ser Ala Pro
                 455                 460                 465

 Ser Glu Ala Cys Arg Arg Gln Ser Ser Gly Ala Gly Ala Glu His
                 470                 475                 480

 Leu Phe Leu Glu Asn Asp Val Ala Glu Ala Leu Leu Gln Glu Ser
                 485                 490                 495

 Glu Glu Ala Ser Glu Leu Lys Pro Val Glu Leu Asp Thr Ser Glu
                 500                 505                 510

 Gly Asn Ile Thr Lys Gln Leu Val Lys Arg Leu Thr Ser Ala Glu
                 515                 520                 525

 Val Pro Met Ala Thr Asp Arg Leu Leu Ser Glu Gly Ser Val Gly
                 530                 535                 540

 Gly Glu Ser Glu Gly Cys Arg Ser Phe Leu Asp Gly Ser Leu Glu
                 545                 550                 555

 Asp Ala Phe Asn Gly Leu Leu Leu Ala Leu Glu Pro His Lys Glu
                 560                 565                 570

 Gln Tyr Lys Glu Phe Gln Asp Leu Asn Gln Glu Val Met Asn Leu
                 575                 580                 585

 Asp Asp Ile Leu Lys Lys
                 590

<210> 1545
<211> 3309
<212> DNA
<213> Homo sapien

<400> 1545
 gcggcgcgcc cgagcctagt ccccacgccg cggcgcgccc gggctccctg 50

 ctgatcccag aacaatcaac catgacgacc gaatctggat cagactcgga 100

 atccaagccg gaccaggagg ccgagcccca ggaggcggcg ggggcgcagg 150

 ggcggcgggg gccgtgccgg agccgcccaa ggaggagcag cagcaggccc 200

 tggagcagtt cgccgccgct gcagcgcaca gcaccccggt gcgagggagg 250

 tcactgacaa ggaacaggag tttgctgcca gggctgcaaa acagctcgaa 300

 tatcagcaat tagaagacga taaactttct cagaaatcat ctagcagtaa 350

 actctctcgg tctccattaa agattgtcaa aaagcctaaa agcatgcagt 400

 gcaaagtgat acttctcgat ggatcagaat atacctgtga tgtagagaaa 450

 cgctccagag gacaagtgct gtttgataaa gtgtgtgaac acttgaactt 500

 gctagagaaa gactactttg ggcttacgta tcgagatgct gaaaaccaga 550

 agaattggtt ggaccctgct aaggaaataa aaaaacaggt tcgaagtggt 600

 gcttggcact tttcatttaa tgtgaaattt tatccaccag accctgccca 650

 actatctgaa gatatcacca ggtactacct ctgcttgcag ttgcgagatg 700

 acatcgtgtc cggaaggctg ccctgctcct ttgttaccct ggccttgctg 750

 ggctcctaca ctgtccagtc agagctcgga gactatgacc cagatgaatg 800

 tgggagcgat tacattagtg agttccgctt tgcaccaaac cacactaaag 850

 aactggaaga caaagtgatc gagctgcaca agagccacag aggaatgacg 900

 ccagcagaag cagagatgca tttcttggaa aatgccaaaa aattatcaat 950

 gtatggggta gatttacatc atgctaagga ctcagaaggg gtagaaatta 1000

 tgttaggagt ttgtgcaagt ggtctgttga tatatcgcga ccggctgcga 1050

 ataaacagat ttgcctggcc caaggttcta aagatttcat acaaacggaa 1100

 caacttttac attaagatcc ggccgggaga gtttgaacaa tttgaaagca 1150

 ccattgggtt taagctgcca aaccatcgag ctgccaagcg tttatggaaa 1200

 gtatgtgttg agcatcatac atttttcaga ctactgttac cagaagcacc 1250

 tcccaagaaa ttcctaacct tgggttccaa gtttcgttat agtggcagga 1300

 cacaagcgca aacgagaaga gccagtgcgt tgatagatcg cccagcacct 1350

 tactttgaac gctcatccag caaacgttat accatgtctc gcagcttgga 1400

 tggagcatca gtgaatgaaa accatgaaat atacatgaag gattctatgt 1450

 ctgctgcaga ggttggtact ggccagtacg ccacaacaaa aggcatctct 1500

 cagaccaact tgatcaccac tgtgactccg gagaagaagg ctgaggagga 1550

 gcgggacgag gaagaggaca aacggaggaa gggggaagaa gtcacgccca 1600

 tctcggccat ccagcacgag ggaaagactg acagtgagcg cacggacacc 1650

 gcagccgacg gggagaccac tgccactgag gagctagaaa aaactcaaga 1700

 tgacctgatg aaacatcaaa ccaacattag cgagctgaaa agaaccttct 1750

 tagaaacctc aacagacact gccgtaacga atgaatggga gaagaggctt 1800

 tccacctccc ccgtgcgact ggccgccagg caggaggatg cccccatgat 1850

 cgaaccactt gtccctgaag agaaaatgga aaccaagacg gagtccagtg 1900

 gatagagacg gaacccaccg tgcaccacct gccgcttagc actgagaagg 1950

 tggtgcagga gaccgtgttg gtggaggagc ggcgtgtggt gcacgcgagt 2000

 ggggatgctt cttactcggc gggagacagc ggggatgctg cagcacagcc 2050

 cgcattcaca ggcattaaag ggaaagaggg ctctgcttga cggagggggc 2100

 taaagaggaa ggaggggagg aggtcgctaa agctgtcctg gaacaggaag 2150

 agacagccgc tgcttcccgt gagcgacaag aggagcagag tgcagccatc 2200

 cacatttcag aaactttgga acaaaaacct cattttgagt cctcaacggt 2250

 gaagacggaa accatcagtt ttggcagtgt ttcaccggga ggagtaaagc 2300

 tagaaatttc cacaagaagt gccagtagtt cacaccgaaa ccaaaaccat 2350

 cacatatgaa tcatcacagg tcgatccagg cacagatctg gagccaggcg 2400

 tgctgatgag tgcacagacg atcacatctg aaaccaccag taccaccacc 2450

 actacccaca tcaccaaaac tgtgaaaggg ggcatttcag agacaagaat 2500

 tgagaagcga atagtcatca cgggggatgc agacattgac catgaccagg 2550

 cgctggctca ggcaattaaa gaggccaaag agcagcaccc tgacatgtca 2600

 gtgaccaaag tagtggtcca taaagagaca gagatcacac cagaagatgg 2650

 agaggattga ccagaggaat aacttagctt gcacatgaat gcagtcatgc 2700

 aaaccgttag gaaaaccaga gcctatatgg agttccctct tctaacccaa 2750

 ctgtacttgt atctgtccgt ggaaaatttc agtccagaag aattgacctt 2800

 gaccattaat aaagacactg gcagagagat cttcccataa taaagcaatc 2850

 tgattcagca tcactaaacc gataatgcat gaagcaacga taaaattaca 2900

 aaagagcagc atttttaatt ttcacaaaat gtctcagttt tcagctatac 2950

 ctgctcgttc ataaccaaca atataaaccg tggtctcatg taacacataa 3000

 acaattcatg cctttcatag tttattatta ttaaagtcta aacaaaattg 3050

 caatttctta ggtaacctta tatttacaat aaatgaagat taccctcaaa 3100

 tgctagaagc tgtctaggtc cgtccggtgt gtcagatttc ctcagattag 3150

 atgtgccaat aaccaagttt attcagtaaa caacttgtac ttgtttcatc 3200

 tggtttatta ctctcaccca taaacagtaa tgactctctg accctctgga 3250

 aatatgtaat gcttccaatc ttgctttgtg tatctcattt aatttgttcc 3300

 ggttaagga 3309

<210> 1546
<211> 503
<212> PRT
<213> Homo sapien

<400> 1546
 Met Gln Cys Lys Val Ile Leu Leu Asp Gly Ser Glu Tyr Thr Cys
   1               5                  10                  15

 Asp Val Glu Lys Arg Ser Arg Gly Gln Val Leu Phe Asp Lys Val
                  20                  25                  30

 Cys Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr
                  35                  40                  45

 Tyr Arg Asp Ala Glu Asn Gln Lys Asn Trp Leu Asp Pro Ala Lys
                  50                  55                  60

 Glu Ile Lys Lys Gln Val Arg Ser Gly Ala Trp His Phe Ser Phe
                  65                  70                  75

 Asn Val Lys Phe Tyr Pro Pro Asp Pro Ala Gln Leu Ser Glu Asp
                  80                  85                  90

 Ile Thr Arg Tyr Tyr Leu Cys Leu Gln Leu Arg Asp Asp Ile Val
                  95                 100                 105

 Ser Gly Arg Leu Pro Cys Ser Phe Val Thr Leu Ala Leu Leu Gly
                 110                 115                 120

 Ser Tyr Thr Val Gln Ser Glu Leu Gly Asp Tyr Asp Pro Asp Glu
                 125                 130                 135

 Cys Gly Ser Asp Tyr Ile Ser Glu Phe Arg Phe Ala Pro Asn His
                 140                 145                 150

 Thr Lys Glu Leu Glu Asp Lys Val Ile Glu Leu His Lys Ser His
                 155                 160                 165

 Arg Gly Met Thr Pro Ala Glu Ala Glu Met His Phe Leu Glu Asn
                 170                 175                 180

 Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His His Ala Lys
                 185                 190                 195

 Asp Ser Glu Gly Val Glu Ile Met Leu Gly Val Cys Ala Ser Gly
                 200                 205                 210

 Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala Trp
                 215                 220                 225

 Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Asn Asn Phe Tyr Ile
                 230                 235                 240

 Lys Ile Arg Pro Gly Glu Phe Glu Gln Phe Glu Ser Thr Ile Gly
                 245                 250                 255

 Phe Lys Leu Pro Asn His Arg Ala Ala Lys Arg Leu Trp Lys Val
                 260                 265                 270

 Cys Val Glu His His Thr Phe Phe Arg Leu Leu Leu Pro Glu Ala
                 275                 280                 285

 Pro Pro Lys Lys Phe Leu Thr Leu Gly Ser Lys Phe Arg Tyr Ser
                 290                 295                 300

 Gly Arg Thr Gln Ala Gln Thr Arg Arg Ala Ser Ala Leu Ile Asp
                 305                 310                 315

 Arg Pro Ala Pro Tyr Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr
                 320                 325                 330

 Met Ser Arg Ser Leu Asp Gly Ala Ser Val Asn Glu Asn His Glu
                 335                 340                 345

 Ile Tyr Met Lys Asp Ser Met Ser Ala Ala Glu Val Gly Thr Gly
                 350                 355                 360

 Gln Tyr Ala Thr Thr Lys Gly Ile Ser Gln Thr Asn Leu Ile Thr
                 365                 370                 375

 Thr Val Thr Pro Glu Lys Lys Ala Glu Glu Glu Arg Asp Glu Glu
                 380                 385                 390

 Glu Asp Lys Arg Arg Lys Gly Glu Glu Val Thr Pro Ile Ser Ala
                 395                 400                 405

 Ile Gln His Glu Gly Lys Thr Asp Ser Glu Arg Thr Asp Thr Ala
                 410                 415                 420

 Ala Asp Gly Glu Thr Thr Ala Thr Glu Glu Leu Glu Lys Thr Gln
                 425                 430                 435

 Asp Asp Leu Met Lys His Gln Thr Asn Ile Ser Glu Leu Lys Arg
                 440                 445                 450

 Thr Phe Leu Glu Thr Ser Thr Asp Thr Ala Val Thr Asn Glu Trp
                 455                 460                 465

 Glu Lys Arg Leu Ser Thr Ser Pro Val Arg Leu Ala Ala Arg Gln
                 470                 475                 480

 Glu Asp Ala Pro Met Ile Glu Pro Leu Val Pro Glu Glu Lys Met
                 485                 490                 495

 Glu Thr Lys Thr Glu Ser Ser Gly
                 500

<210> 1547
<211> 785
<212> DNA
<213> Homo sapien

<400> 1547
 gaattgcacc atgccaaact acaaactcac ttattttaat atgaggggga 50

 gagcagaaat tattcgttac atatttgctt atttggacat acagtatgaa 100

 gaccacagaa tagaacaagc tgactggcct gaaatcaaat caactctccc 150

 atttggaaaa atccccattt tggaagttga tggacttact cttcaccaga 200

 gcctagcaat agcaagatat ttgaccaaaa acacagattt ggctggaaac 250

 acagaaatgg aacaatgtca tgttgatgct attgtggaca ctctggatga 300

 tttcatgtca tgttttcctt gggcagagaa aaagcaagat gtgaaagagc 350

 agatgttcaa tgagctgctc acgtataatg cgcctcatct tatgcaagac 400

 ttggacacat atttaggggg gagagaatgg cttattggta actctgtaac 450

 ttgggcagac ttctactggg agatttgcag taccacactt ttggtcttta 500

 agcctgacct gttagacaac catccaaggc tggtgacttt acggaagaaa 550

 gtccaagcca ttcctgccgt cgctaactgg ataaaacgaa ggccccaaac 600

 caaactctag ctgatccatg ttgccttcaa gtttgttttt ctcgggggca 650

 tctctctcat cagataagac agctacatca gcctgccaga taatccacat 700

 gctccctccc cagctccact aagattttca ctttagccat attctgattt 750

 ttaaaaagga aaataaaaac aaatctttct tcagt 785

<210> 1548
<211> 199
<212> PRT
<213> Homo sapien

<400> 1548
 Met Pro Asn Tyr Lys Leu Thr Tyr Phe Asn Met Arg Gly Arg Ala
   1               5                  10                  15

 Glu Ile Ile Arg Tyr Ile Phe Ala Tyr Leu Asp Ile Gln Tyr Glu
                  20                  25                  30

 Asp His Arg Ile Glu Gln Ala Asp Trp Pro Glu Ile Lys Ser Thr
                  35                  40                  45

 Leu Pro Phe Gly Lys Ile Pro Ile Leu Glu Val Asp Gly Leu Thr
                  50                  55                  60

 Leu His Gln Ser Leu Ala Ile Ala Arg Tyr Leu Thr Lys Asn Thr
                  65                  70                  75

 Asp Leu Ala Gly Asn Thr Glu Met Glu Gln Cys His Val Asp Ala
                  80                  85                  90

 Ile Val Asp Thr Leu Asp Asp Phe Met Ser Cys Phe Pro Trp Ala
                  95                 100                 105

 Glu Lys Lys Gln Asp Val Lys Glu Gln Met Phe Asn Glu Leu Leu
                 110                 115                 120

 Thr Tyr Asn Ala Pro His Leu Met Gln Asp Leu Asp Thr Tyr Leu
                 125                 130                 135

 Gly Gly Arg Glu Trp Leu Ile Gly Asn Ser Val Thr Trp Ala Asp
                 140                 145                 150

 Phe Tyr Trp Glu Ile Cys Ser Thr Thr Leu Leu Val Phe Lys Pro
                 155                 160                 165

 Asp Leu Leu Asp Asn His Pro Arg Leu Val Thr Leu Arg Lys Lys
                 170                 175                 180

 Val Gln Ala Ile Pro Ala Val Ala Asn Trp Ile Lys Arg Arg Pro
                 185                 190                 195

 Gln Thr Lys Leu


<210> 1549
<211> 1261
<212> DNA
<213> Homo sapien

<400> 1549
 gcagttatca tagagcacag tccctcacat cacacagctg cagagatgag 50

 taaacaaaga ggaaccttct cagaagtgag tctggcccag gacccaaagc 100

 ggcagcaaag gaaacctaaa ggcaataaaa gctccatttc aggaaccgaa 150

 caggaaatat tccaagtaga attaaatctt caaaatcctt ccctgaatca 200

 tcaagggatt gataaaatat atgactgcca aggtttactg ccacctccag 250

 agaagctcac tgccgaggtc ctaggaatca tttgcattgt cctgatggcc 300

 actgtgttaa aaacaatagt tcttattcct ttcctggagc agaacaattc 350

 ttccccgaat acaagaacgc agaaagcacg tcattgtggc cattgtcctg 400

 aggagtggat tacatattcc aacagttgtt attacattgg taaggaaaga 450

 agaacttggg aagagagttt gctggcctgt acttcgaaga actccagtct 500

 gctttctata gataatgaag aagaaataaa atttctggcc agcattttac 550

 cttcctcatg gattggtgtg tttcgtaaca gcagtcatca tccatgggtg 600

 acaataaatg gtttggcttt caaacataag ataaaagact cagataatgc 650

 tgaacttaac tgtgcagtgc tacaagtaaa tcgacttaaa tcagcccagt 700

 gtggatcttc aatgatatat cattgtaagc ataagcttta gaagtaaagc 750

 atttgcgttt acagtgcatc agatacattt tatatttctt aaaatagaaa 800

 tattatgatt gcataaatct gaaaatgaat tatgttattt gctctaatac 850

 aaaaattcta aatcaattat tgaaatagga tgcacacaat tactaaagta 900

 cagacatcct agcatttgtg tcgggctcat tttgctcaac atggtatttg 950

 tggttttcag cctttctaaa agttgcatgt tatgtgagtc agcttatagg 1000

 aagtaccaag aacagtcaaa cccatggaga cagaaagtag aatagtggtt 1050

 gccaatgtct cagggaggtt gaaataggag atgaccacta attgatagaa 1100

 cgtttctttg tgtcgtgatg aaaactttct aaatttcagt aatggtgatg 1150

 gttgtaactt tgcgaatata ctaaacatca ttgattttta atcattttaa 1200

 gtgcatgaaa tgtatgcttt gtacatgaca cttcaataaa gctatccaga 1250

 aaaaaaaaaa a 1261

<210> 1550
<211> 231
<212> PRT
<213> Homo sapien

<400> 1550
 Met Ser Lys Gln Arg Gly Thr Phe Ser Glu Val Ser Leu Ala Gln
   1               5                  10                  15

 Asp Pro Lys Arg Gln Gln Arg Lys Pro Lys Gly Asn Lys Ser Ser
                  20                  25                  30

 Ile Ser Gly Thr Glu Gln Glu Ile Phe Gln Val Glu Leu Asn Leu
                  35                  40                  45

 Gln Asn Pro Ser Leu Asn His Gln Gly Ile Asp Lys Ile Tyr Asp
                  50                  55                  60

 Cys Gln Gly Leu Leu Pro Pro Pro Glu Lys Leu Thr Ala Glu Val
                  65                  70                  75

 Leu Gly Ile Ile Cys Ile Val Leu Met Ala Thr Val Leu Lys Thr
                  80                  85                  90

 Ile Val Leu Ile Pro Phe Leu Glu Gln Asn Asn Ser Ser Pro Asn
                  95                 100                 105

 Thr Arg Thr Gln Lys Ala Arg His Cys Gly His Cys Pro Glu Glu
                 110                 115                 120

 Trp Ile Thr Tyr Ser Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg
                 125                 130                 135

 Arg Thr Trp Glu Glu Ser Leu Leu Ala Cys Thr Ser Lys Asn Ser
                 140                 145                 150

 Ser Leu Leu Ser Ile Asp Asn Glu Glu Glu Ile Lys Phe Leu Ala
                 155                 160                 165

 Ser Ile Leu Pro Ser Ser Trp Ile Gly Val Phe Arg Asn Ser Ser
                 170                 175                 180

 His His Pro Trp Val Thr Ile Asn Gly Leu Ala Phe Lys His Lys
                 185                 190                 195

 Ile Lys Asp Ser Asp Asn Ala Glu Leu Asn Cys Ala Val Leu Gln
                 200                 205                 210

 Val Asn Arg Leu Lys Ser Ala Gln Cys Gly Ser Ser Met Ile Tyr
                 215                 220                 225

 His Cys Lys His Lys Leu
                 230

<210> 1551
<211> 822
<212> DNA
<213> Homo sapien

<400> 1551
 gggctgctcc acgcttttgc cggagacaga gactgacatg gaacagggga 50

 agggcctggc tgtcctcatc ctggctatca ttcttcttca aggtactttg 100

 gcccagtcaa tcaaaggaaa ccacttggtt aaggtgtatg actatcaaga 150

 agatggttcg gtacttctga cttgtgatgc agaagccaaa aatatcacat 200

 ggtttaaaga tgggaagatg atcggcttcc taactgaaga taaaaaaaaa 250

 tggaatctgg gaagtaatgc caaggaccct cgagggatgt atcagtgtaa 300

 aggatcacag aacaagtcaa aaccactcca agtgtattac agaatgtgtc 350

 agaactgcat tgaactaaat gcagccacca tatctggctt tctctttgct 400

 gaaatcgtca gcattttcgt ccttgctgtt ggggtctact tcattgctgg 450

 acaggatgga gttcgccagt cgagagcttc agacaagcag actctgttgc 500

 ccaatgacca gctctaccag cccctcaagg atcgagaaga tgaccagtac 550

 agccaccttc aaggaaacca gttgaggagg aattgaactc aggactcaga 600

 gtagtccagg tgttctcctc ctattcagtt cccagaatca aagcaatgca 650

 ttttggaaag ctcctagcag agagactttc agccctaaat ctagactcaa 700

 ggttcccaga gatgacaaat ggagaagaaa ggccatcaga gcaaatttgg 750

 gggtttctca aataaaataa aaataaaaac aaatactgtg tttcagaagc 800

 gccacctatt ggggaaaatt gt 822

<210> 1552
<211> 182
<212> PRT
<213> Homo sapien

<400> 1552
 Met Glu Gln Gly Lys Gly Leu Ala Val Leu Ile Leu Ala Ile Ile
   1               5                  10                  15

 Leu Leu Gln Gly Thr Leu Ala Gln Ser Ile Lys Gly Asn His Leu
                  20                  25                  30

 Val Lys Val Tyr Asp Tyr Gln Glu Asp Gly Ser Val Leu Leu Thr
                  35                  40                  45

 Cys Asp Ala Glu Ala Lys Asn Ile Thr Trp Phe Lys Asp Gly Lys
                  50                  55                  60

 Met Ile Gly Phe Leu Thr Glu Asp Lys Lys Lys Trp Asn Leu Gly
                  65                  70                  75

 Ser Asn Ala Lys Asp Pro Arg Gly Met Tyr Gln Cys Lys Gly Ser
                  80                  85                  90

 Gln Asn Lys Ser Lys Pro Leu Gln Val Tyr Tyr Arg Met Cys Gln
                  95                 100                 105

 Asn Cys Ile Glu Leu Asn Ala Ala Thr Ile Ser Gly Phe Leu Phe
                 110                 115                 120

 Ala Glu Ile Val Ser Ile Phe Val Leu Ala Val Gly Val Tyr Phe
                 125                 130                 135

 Ile Ala Gly Gln Asp Gly Val Arg Gln Ser Arg Ala Ser Asp Lys
                 140                 145                 150

 Gln Thr Leu Leu Pro Asn Asp Gln Leu Tyr Gln Pro Leu Lys Asp
                 155                 160                 165

 Arg Glu Asp Asp Gln Tyr Ser His Leu Gln Gly Asn Gln Leu Arg
                 170                 175                 180

 Arg Asn


<210> 1553
<211> 2564
<212> DNA
<213> Homo sapien

<400> 1553
 gatttcagtt gaaagatgtg tttttgtgag tagagcaccg cagaagaact 50

 gaagactgtt gtgtgctccc cgcagaaggg gctaccatga tcctttcctc 100

 ctataacacc atccagtcgg ttttctgttg ctgctgttgc tgttcagtgc 150

 agaagcgaca aatgagaaca cagataagcc tgagcacaga tgaagagctt 200

 ccagaaaaat acacccagca tcgcaggccg tggctcagcc aattgtcaaa 250

 taagaagcaa tccaacacgg gccgtgtgca gccgtcaaaa cgaaagccac 300

 tgcctcccct cccaccctct gaggttgctg aagagaagat ccaagtcaag 350

 gcactttatg attttctgcc cagagaaccc tgtaatttag ccttaaggag 400

 agcagaagaa tacctgatac tggagaaata caatcctcac tggtggaagg 450

 caagagaccg tttggggaat gaaggcttaa tcccaagcaa ctatgtgact 500

 gaaaacaaaa taactaattt agaaatatat gagtggtacc atagaaacat 550

 taccagaaat caggcagaac atctattgag acaagagtct aaagaaggtg 600

 catttattgt cagagattca agacatttag gatcctacac aatttccgta 650

 tttatgggag ctagaagaag tacggaggct gccataaaac attatcagat 700

 aaaaaagaat gactcaggac agtggtatgt ggctgaaaga cacgcctttc 750

 aatcaatccc tgagttaatc tggtatcacc agcacaatgc agccggtctc 800

 atgactcgtc tccgatatcc agttgggctg atgggcagtt gtttaccagc 850

 cacagctggg tttagctacg aaaagtggga gatagatcca tctgagttgg 900

 cttttataaa ggagattgga agcggtcagt ttggagtggt ccatttaggt 950

 gaatggcggt cacatatcca ggtagctatc aaggccatca atgaaggctc 1000

 catgtctgaa gaggatttca ttgaagaggc caaagtgatg atgaaattat 1050

 ctcattcaaa gctagtgcaa ctttatggag tctgtataca gcggaagccc 1100

 ctttacattg tgacagagtt catggaaaat ggctgcctgc ttaactatct 1150

 cagggagaat aaaggaaagc ttaggaagga aatgctactg agtgtatgcc 1200

 aggatatatg tgaaggaatg gaatatctgg agaggaatgg ctatattcat 1250

 agggatttgg cggcaaggaa ttgtttggtc agttcaacat gcatagtaaa 1300

 aatttcagac tttggaatga caaggtacgt tttggatgat gagtatgtca 1350

 gttcttttgg agccaagttc ccaatcaagt ggtcccctcc tgaagttttt 1400

 cttttcaata agtacagcag taaatctgat gtctggtcat ttggagtttt 1450

 aatgtgggaa gtttttacag aaggaaaaat gccttttgaa aataagtcaa 1500

 atttgcaagt cgtggaagct atttctgaag gcttcaggct atatcgccct 1550

 cacctggcac caatgtccat atatgaagtc atgtacagct gctggcatga 1600

 gaaacctgaa ggccgcccta catttgcgga gctgctgcgg gctgtcacag 1650

 agattgcgga aacctggtga ccggaaacag aatgccaacc caaagagtca 1700

 tcttgcaaaa ctgtcattta ttgtgaatat cttcaccata tggggtcact 1750

 tatggtgaat atctttcttc agagttgctg actcttgaaa acagtgcaaa 1800

 gatcacagtt tttaaaagtt ttaaaaattt aagaatattc acacaatcgt 1850

 ttttctatgt gtgagaggga tttgcacact cttatttttc tgtaaaatat 1900

 ttcacatccc aaatgtgaag aagtgaaaaa gacttcgcag cagtcttcat 1950

 tgtggtgctc ttcatgatca tagccccagg aacccttgag gttcttcttc 2000

 acaaggctga gagtgcttcc ttcttgaaga cgagtgtcat tcatcacttc 2050

 agtgatccat gcatagaata tgaaaataaa ttcttccaac tcatgggata 2100

 aaggggactc ccttgaagaa tttcatgttt ttgggctgta tagctcttta 2150

 cagaaaatgc acctttataa atcacatgaa tgttagtatt ctggaaatgt 2200

 cttttgttaa tataatcttc ccatgttatt taacaaattg tttttgcaca 2250

 tatctgatta tattgaaagc agtttttttg cattcgagtt ttaaacactg 2300

 ttataaaatg tagccaaagc tcacctttga acagatcccg gtgacattct 2350

 atttccagga aaatccggaa cctgatttta gttctgtgat tttacacttt 2400

 ttacatgtga gattggacag tttcagaggc cttattttgt catactaagt 2450

 gtctcctgta attttcagga agatgatttg ttctttccag aagaggagac 2500

 aaaagcaaga tagccaaatg tgacatcaag ctccattgtt tcggaaatcc 2550

 aggattttga attc 2564

<210> 1554
<211> 527
<212> PRT
<213> Homo sapien

<400> 1554
 Met Ile Leu Ser Ser Tyr Asn Thr Ile Gln Ser Val Phe Cys Cys
   1               5                  10                  15

 Cys Cys Cys Cys Ser Val Gln Lys Arg Gln Met Arg Thr Gln Ile
                  20                  25                  30

 Ser Leu Ser Thr Asp Glu Glu Leu Pro Glu Lys Tyr Thr Gln His
                  35                  40                  45

 Arg Arg Pro Trp Leu Ser Gln Leu Ser Asn Lys Lys Gln Ser Asn
                  50                  55                  60

 Thr Gly Arg Val Gln Pro Ser Lys Arg Lys Pro Leu Pro Pro Leu
                  65                  70                  75

 Pro Pro Ser Glu Val Ala Glu Glu Lys Ile Gln Val Lys Ala Leu
                  80                  85                  90

 Tyr Asp Phe Leu Pro Arg Glu Pro Cys Asn Leu Ala Leu Arg Arg
                  95                 100                 105

 Ala Glu Glu Tyr Leu Ile Leu Glu Lys Tyr Asn Pro His Trp Trp
                 110                 115                 120

 Lys Ala Arg Asp Arg Leu Gly Asn Glu Gly Leu Ile Pro Ser Asn
                 125                 130                 135

 Tyr Val Thr Glu Asn Lys Ile Thr Asn Leu Glu Ile Tyr Glu Trp
                 140                 145                 150

 Tyr His Arg Asn Ile Thr Arg Asn Gln Ala Glu His Leu Leu Arg
                 155                 160                 165

 Gln Glu Ser Lys Glu Gly Ala Phe Ile Val Arg Asp Ser Arg His
                 170                 175                 180

 Leu Gly Ser Tyr Thr Ile Ser Val Phe Met Gly Ala Arg Arg Ser
                 185                 190                 195

 Thr Glu Ala Ala Ile Lys His Tyr Gln Ile Lys Lys Asn Asp Ser
                 200                 205                 210

 Gly Gln Trp Tyr Val Ala Glu Arg His Ala Phe Gln Ser Ile Pro
                 215                 220                 225

 Glu Leu Ile Trp Tyr His Gln His Asn Ala Ala Gly Leu Met Thr
                 230                 235                 240

 Arg Leu Arg Tyr Pro Val Gly Leu Met Gly Ser Cys Leu Pro Ala
                 245                 250                 255

 Thr Ala Gly Phe Ser Tyr Glu Lys Trp Glu Ile Asp Pro Ser Glu
                 260                 265                 270

 Leu Ala Phe Ile Lys Glu Ile Gly Ser Gly Gln Phe Gly Val Val
                 275                 280                 285

 His Leu Gly Glu Trp Arg Ser His Ile Gln Val Ala Ile Lys Ala
                 290                 295                 300

 Ile Asn Glu Gly Ser Met Ser Glu Glu Asp Phe Ile Glu Glu Ala
                 305                 310                 315

 Lys Val Met Met Lys Leu Ser His Ser Lys Leu Val Gln Leu Tyr
                 320                 325                 330

 Gly Val Cys Ile Gln Arg Lys Pro Leu Tyr Ile Val Thr Glu Phe
                 335                 340                 345

 Met Glu Asn Gly Cys Leu Leu Asn Tyr Leu Arg Glu Asn Lys Gly
                 350                 355                 360

 Lys Leu Arg Lys Glu Met Leu Leu Ser Val Cys Gln Asp Ile Cys
                 365                 370                 375

 Glu Gly Met Glu Tyr Leu Glu Arg Asn Gly Tyr Ile His Arg Asp
                 380                 385                 390

 Leu Ala Ala Arg Asn Cys Leu Val Ser Ser Thr Cys Ile Val Lys
                 395                 400                 405

 Ile Ser Asp Phe Gly Met Thr Arg Tyr Val Leu Asp Asp Glu Tyr
                 410                 415                 420

 Val Ser Ser Phe Gly Ala Lys Phe Pro Ile Lys Trp Ser Pro Pro
                 425                 430                 435

 Glu Val Phe Leu Phe Asn Lys Tyr Ser Ser Lys Ser Asp Val Trp
                 440                 445                 450

 Ser Phe Gly Val Leu Met Trp Glu Val Phe Thr Glu Gly Lys Met
                 455                 460                 465

 Pro Phe Glu Asn Lys Ser Asn Leu Gln Val Val Glu Ala Ile Ser
                 470                 475                 480

 Glu Gly Phe Arg Leu Tyr Arg Pro His Leu Ala Pro Met Ser Ile
                 485                 490                 495

 Tyr Glu Val Met Tyr Ser Cys Trp His Glu Lys Pro Glu Gly Arg
                 500                 505                 510

 Pro Thr Phe Ala Glu Leu Leu Arg Ala Val Thr Glu Ile Ala Glu
                 515                 520                 525

 Thr Trp


<210> 1555
<211> 2298
<212> DNA
<213> Homo sapien

<400> 1555
 tttttggcgg ggcctttgtc cctcgctgtg gcctgagctc caggtctcgt 50

 cttcagcgct ctgtgtcctc tgctcctaga ggtccaggct ctgtggccct 100

 gtgacctgca ggtattggga gatctacagc taagacgcca ggaacccctg 150

 gaagcctaga aatggagaac ctgaagtctg gagtgtatcc tctcaaggaa 200

 gcaagtggat gccctggggc tgacaggaat cttctggtgt actcttttta 250

 tgaaaagggg ccattgacat ttagggatgt ggccatagaa ttttctctgg 300

 aggagtggca atgcctggac actgctcagc aggatttgta tagaaaagtg 350

 atgttagaga actacagaaa cctggtcttc ttggcaggta ttgctgtttc 400

 taagccagac ctgatcacct gtctagagca aggaaaagag ccctggaata 450

 tgaagagaca tgcgatggta gatcaacccc cagttacata ttctcatttt 500

 gcccaagacc tttggccaga gcagggcata aaagattctt tccaagaagt 550

 catattgaga agatatggaa aatgtggaca tgaagattta cagttaagaa 600

 caggctgtag aagtgtggat gagtgtaatc tgcacaaaga atgttatgat 650

 gaactaaacc agtgtttgac aactacccag agtgaaatat ttcaatatga 700

 taaatatgtg aatgtctttt ataaattttc aaatccaaat atacaaaaga 750

 taagacatac tggaaagaag cctttcaaat gtaaaaaatg tgacaaatcg 800

 ttttgcatgc ttttacacct aactcaacat aaaagaattc atattaggga 850

 aaattcttac caatgtgaag aatgtggtaa agtctttaac tggttctcaa 900

 cccttactag acacagaaga attcatactg gagagaaacc ctacaaatgt 950

 gaacaatgtg gcaaagcttt taagcagtcc tcaaccctta ctacacataa 1000

 gataattcat actggagaga aaccctacag atgtgaaaat gtggcaaaac 1050

 ctttaaccgg tcctcacacc ttactacaca taaaagaatt catactggag 1100

 agaaacccta cagatgtgaa gaatgtggca gagcttttaa ccggtcctca 1150

 caccttacta cacataagat tattcatact ggagagaaac cctacaaatg 1200

 tgaagaatgt ggcaaagctt ttaaccaatc ctcaaccctt actacacata 1250

 agataattca tgctggagag aaaccttaca aatgtgaaga atgtggcaaa 1300

 gctttttacc gattctcata ccttactaaa cataagataa ttcatactgg 1350

 agagaaattc tacaaatgtg aagaatgtgg caaaggcttt aattggtcct 1400

 cgacccttac taaacataaa agaattcata ctggagagaa accctacaaa 1450

 tgtgaacaat gtggcaaagc ttttaatgag tcctcaaacc ttactgcaca 1500

 taagataatt catactggag agaaacccta caaatgtgaa gaatgtggca 1550

 aagcctttaa ccggtcccca aaacttactg cacataaggt aattcattct 1600

 ggagagaaac cctacaaatg tgaagaatgt ggcaaagctt ttaaccaatt 1650

 ctcaaacctt actaaacata agataactca tattggagat acatcttaca 1700

 aatacctaga atgtgataaa gcctttagcc agtcttcaac tcttactaaa 1750

 cataaggtaa ttcatactgg agagaaaccc tacaactgtg aagaatacgg 1800

 caaagctttc aaccagtcct caaaccttat tgaacaaagt aattcatact 1850

 ggagagaaac cctacaaatg tgaagattgt ggcaaagcct ctaacccgtc 1900

 ctgaattctt actaaacata agaacattca tactgaagag gaaccctatg 1950

 agtgtgaaga atatggcaaa gccttcaaca agtcctcaat tcttaccaga 2000

 cataagataa ttctggctgg gtgcggtggc tcacacctgt aatcccagca 2050

 ctttgggagg ctgagacggg tgaattacat gaggttggga gttcgagacc 2100

 agcctgacca acatggtgaa atcctgtctc tactaaaaat acaaaattag 2150

 ccatgcgtag tggtgcatgc ctgtaatccc agctactcgg gaggctgagg 2200

 caggagaatt gcttgaaccc gggaggcaga ggttgaagtg agctgagatc 2250

 gcgccattgc actccagcct gggcaacaag agtggcactc catctcag 2298

<210> 1556
<211> 364
<212> PRT
<213> Homo sapien

<400> 1556
 Met Glu Asn Leu Lys Ser Gly Val Tyr Pro Leu Lys Glu Ala Ser
   1               5                  10                  15

 Gly Cys Pro Gly Ala Asp Arg Asn Leu Leu Val Tyr Ser Phe Tyr
                  20                  25                  30

 Glu Lys Gly Pro Leu Thr Phe Arg Asp Val Ala Ile Glu Phe Ser
                  35                  40                  45

 Leu Glu Glu Trp Gln Cys Leu Asp Thr Ala Gln Gln Asp Leu Tyr
                  50                  55                  60

 Arg Lys Val Met Leu Glu Asn Tyr Arg Asn Leu Val Phe Leu Ala
                  65                  70                  75

 Gly Ile Ala Val Ser Lys Pro Asp Leu Ile Thr Cys Leu Glu Gln
                  80                  85                  90

 Gly Lys Glu Pro Trp Asn Met Lys Arg His Ala Met Val Asp Gln
                  95                 100                 105

 Pro Pro Val Thr Tyr Ser His Phe Ala Gln Asp Leu Trp Pro Glu
                 110                 115                 120

 Gln Gly Ile Lys Asp Ser Phe Gln Glu Val Ile Leu Arg Arg Tyr
                 125                 130                 135

 Gly Lys Cys Gly His Glu Asp Leu Gln Leu Arg Thr Gly Cys Arg
                 140                 145                 150

 Ser Val Asp Glu Cys Asn Leu His Lys Glu Cys Tyr Asp Glu Leu
                 155                 160                 165

 Asn Gln Cys Leu Thr Thr Thr Gln Ser Glu Ile Phe Gln Tyr Asp
                 170                 175                 180

 Lys Tyr Val Asn Val Phe Tyr Lys Phe Ser Asn Pro Asn Ile Gln
                 185                 190                 195

 Lys Ile Arg His Thr Gly Lys Lys Pro Phe Lys Cys Lys Lys Cys
                 200                 205                 210

 Asp Lys Ser Phe Cys Met Leu Leu His Leu Thr Gln His Lys Arg
                 215                 220                 225

 Ile His Ile Arg Glu Asn Ser Tyr Gln Cys Glu Glu Cys Gly Lys
                 230                 235                 240

 Val Phe Asn Trp Phe Ser Thr Leu Thr Arg His Arg Arg Ile His
                 245                 250                 255

 Thr Gly Glu Lys Pro Tyr Lys Cys Glu Gln Cys Gly Lys Ala Phe
                 260                 265                 270

 Lys Gln Ser Ser Thr Leu Thr Thr His Lys Ile Ile His Thr Gly
                 275                 280                 285

 Glu Lys Pro Tyr Arg Cys Glu Asn Val Ala Lys Pro Leu Thr Gly
                 290                 295                 300

 Pro His Thr Leu Leu His Ile Lys Glu Phe Ile Leu Glu Arg Asn
                 305                 310                 315

 Pro Thr Asp Val Lys Asn Val Ala Glu Leu Leu Thr Gly Pro His
                 320                 325                 330

 Thr Leu Leu His Ile Arg Leu Phe Ile Leu Glu Arg Asn Pro Thr
                 335                 340                 345

 Asn Val Lys Asn Val Ala Lys Leu Leu Thr Asn Pro Gln Pro Leu
                 350                 355                 360

 Leu His Ile Arg


<210> 1557
<211> 2425
<212> DNA
<213> Homo sapien

<400> 1557
 atgtggtgga gagttctcag cttgctggca tggttcccct tgcaagaggc 50

 ctctctgact aaccacacag aaaccatcac cgtggaggaa ggccagacgc 100

 tcactctaaa gtgtgtcact tctctgagga agaactcctc cctccagtgg 150

 ctgaccccct cagggttcac cattttttta aatgagtatc ctgctttaaa 200

 aaattccaaa taccagcttc ttcatcactc ggccaatcag ctctccatca 250

 ctgtgcctaa cgtaaccctg caagatgaag gcgtgtacaa gtgcttacat 300

 tacagcgact ctgtaagcac aaaggaagtg aaagtgattg tgctggcaac 350

 tcctttcaag ccaatcctgg aagcttcagt tatcagaaag caaaatggag 400

 aagaacatgt tgtactcatg tgctccacca tgagaagcaa gccccctccg 450

 cagataacct ggctacttgg gaatagcatg gaagtgtccg gtggaacgct 500

 ccatgaattt gaaactgatg ggaagaaatg taatactacc agcactctca 550

 taatccacac ttatggcaaa aattcaacgg tggactgcat tatccgacac 600

 agaggcctgc aagggagaaa actagtagca cccttccggt ttgaagattt 650

 ggttactgat gaagagacag cttcagatgc tctggagaga aactctctat 700

 cctctcaaga cccacagcag cccaccagta ctgtctcagt aacggaagat 750

 tctagtacat cggagattga caaggaagag aaagaacaaa ccactcaaga 800

 tcctgacttg accaccgaag caaatcctca gtatttagga ctggcaagaa 850

 agaaaagtgg catcctgctg ctcacgctgg tgtccttcct cattttcata 900

 ctcttcatca tagtccagct cttcatcatg aagctgagga aagcacatgt 950

 gatatggaag agagaaaacg aagtttcaga acacacacta gaaagttaca 1000

 gatcaaggtc aaataatgaa gaaacatcat ctgaagagaa aaatggccaa 1050

 tcttcccacc ctatgcgttg catgaactac atcacaaagt tgtactcaga 1100

 agcaaaaaca aagaggaagg aaaatgtaca acattcaaaa ttagaagaaa 1150

 agcacatcca agtaccagag agtattgtgt agtgctctct gcaatggaac 1200

 atgtgatttc agggttgccg cagtgtcacc tcagtggacc agcctggggg 1250

 aaggagctta attgctgaga cattaataat gacctcttag tgcaatgcaa 1300

 gatggtgtcc tcggataatg atctgccccg gagctagggc agcaacatga 1350

 ggaccaaacc atgcacataa agcttgtagt ttaaaaaaga aaagcaaaaa 1400

 aataattatg cctgacacta cttcagagca ggaggattct acgaagcctt 1450

 ggggatcagg gtcagtgtga gcagctaaca tcctacctca aatggaacag 1500

 gattttttga tgctttgctc taatggaact gttttaaaaa tttttttttc 1550

 tttttaatat tttcttctgg tcacaaaata aagaaatttg ggatgcaaag 1600

 tacctaaaga tctctgatcc taagaagtta cttctggcca ggcgcggtgg 1650

 ctcatgcctg taatcctagc actttgggag gctgaggtag gcagatcact 1700

 tgaggtcagg agttggagac cagcctggcc aacatagtga aaccccgtct 1750

 ctactaaaaa tgcaaaaatt agccaggcgt agtggtgcgc acctgtagtc 1800

 tcagatactt gggaggctga gggtggagaa tcgcttgaac ctgggaggtg 1850

 gagattgcag tgagtcaaga tctcaccact gaactccagc ctgggcgaca 1900

 gagggagact ctgtctcaaa aaaaaagaag ttacttccaa gacagacttt 1950

 taacatgtaa ccagcacaaa gcaatgtcag ggaggagtga tacatgacaa 2000

 taaatgagtc agatgagcaa gaaggcccca gaacccatgc cccaaggcac 2050

 aaagaggagc tcagggtagg cccaaagatt cgaattcctt agattactaa 2100

 atcacatgag cggaccttgt ctgtcagata agatttttac ctggaaattc 2150

 catgaccaat acatgtgcaa aagaaaatga tgggttgaat ttactgatta 2200

 ttgacctaat ggatggcttt ttaaaatgtt ttaataaaaa gcagaataga 2250

 tgtttgtttt tctagtggtt ataccaagct atacttcctg ttttcacgtg 2300

 tgaaagtaac atgggacatg cctttctttt ccgatcagtt tatttaagct 2350

 atacagcaaa ctttggcatt tatgtggagc atttctcatt gttggaatct 2400

 gaataaacca attacaaaat aaaaa 2425

<210> 1558
<211> 393
<212> PRT
<213> Homo sapien

<400> 1558
 Met Trp Trp Arg Val Leu Ser Leu Leu Ala Trp Phe Pro Leu Gln
   1               5                  10                  15

 Glu Ala Ser Leu Thr Asn His Thr Glu Thr Ile Thr Val Glu Glu
                  20                  25                  30

 Gly Gln Thr Leu Thr Leu Lys Cys Val Thr Ser Leu Arg Lys Asn
                  35                  40                  45

 Ser Ser Leu Gln Trp Leu Thr Pro Ser Gly Phe Thr Ile Phe Leu
                  50                  55                  60

 Asn Glu Tyr Pro Ala Leu Lys Asn Ser Lys Tyr Gln Leu Leu His
                  65                  70                  75

 His Ser Ala Asn Gln Leu Ser Ile Thr Val Pro Asn Val Thr Leu
                  80                  85                  90

 Gln Asp Glu Gly Val Tyr Lys Cys Leu His Tyr Ser Asp Ser Val
                  95                 100                 105

 Ser Thr Lys Glu Val Lys Val Ile Val Leu Ala Thr Pro Phe Lys
                 110                 115                 120

 Pro Ile Leu Glu Ala Ser Val Ile Arg Lys Gln Asn Gly Glu Glu
                 125                 130                 135

 His Val Val Leu Met Cys Ser Thr Met Arg Ser Lys Pro Pro Pro
                 140                 145                 150

 Gln Ile Thr Trp Leu Leu Gly Asn Ser Met Glu Val Ser Gly Gly
                 155                 160                 165

 Thr Leu His Glu Phe Glu Thr Asp Gly Lys Lys Cys Asn Thr Thr
                 170                 175                 180

 Ser Thr Leu Ile Ile His Thr Tyr Gly Lys Asn Ser Thr Val Asp
                 185                 190                 195

 Cys Ile Ile Arg His Arg Gly Leu Gln Gly Arg Lys Leu Val Ala
                 200                 205                 210

 Pro Phe Arg Phe Glu Asp Leu Val Thr Asp Glu Glu Thr Ala Ser
                 215                 220                 225

 Asp Ala Leu Glu Arg Asn Ser Leu Ser Ser Gln Asp Pro Gln Gln
                 230                 235                 240

 Pro Thr Ser Thr Val Ser Val Thr Glu Asp Ser Ser Thr Ser Glu
                 245                 250                 255

 Ile Asp Lys Glu Glu Lys Glu Gln Thr Thr Gln Asp Pro Asp Leu
                 260                 265                 270

 Thr Thr Glu Ala Asn Pro Gln Tyr Leu Gly Leu Ala Arg Lys Lys
                 275                 280                 285

 Ser Gly Ile Leu Leu Leu Thr Leu Val Ser Phe Leu Ile Phe Ile
                 290                 295                 300

 Leu Phe Ile Ile Val Gln Leu Phe Ile Met Lys Leu Arg Lys Ala
                 305                 310                 315

 His Val Ile Trp Lys Arg Glu Asn Glu Val Ser Glu His Thr Leu
                 320                 325                 330

 Glu Ser Tyr Arg Ser Arg Ser Asn Asn Glu Glu Thr Ser Ser Glu
                 335                 340                 345

 Glu Lys Asn Gly Gln Ser Ser His Pro Met Arg Cys Met Asn Tyr
                 350                 355                 360

 Ile Thr Lys Leu Tyr Ser Glu Ala Lys Thr Lys Arg Lys Glu Asn
                 365                 370                 375

 Val Gln His Ser Lys Leu Glu Glu Lys His Ile Gln Val Pro Glu
                 380                 385                 390

 Ser Ile Val


<210> 1559
<211> 1993
<212> DNA
<213> Homo sapien

<400> 1559
 gctgcagaag ctgccgccac ctccaatgca caaggtgtct catctgaaaa 50

 gaaacctgag ccccagggag gcggcgcgga gcgaccctgg cagagctggc 100

 gcaaacaggg cgagaggtcg ctgggcagcg ttcgaggacc agagggagct 150

 cggccacaga agaccccagt gatctgatcc cgggatcccg gctccaagct 200

 ctcctcgcat tttacagatt tcacccccgc gactatctcc ccaaaacgga 250

 gcctttatat caagagaagg tgcgggagct ggggcaacca ggactttctc 300

 gggcacccaa gatgcgctcc attaggaaga ggtggacgat ctgcacaata 350

 agtctgctcc tgatctttta taagacaaaa gaaatagcaa gaactgagga 400

 gcaccaggag acgcaactca tcggagatgg tgaattgtct ttgagtcggt 450

 cacttgtcaa tagctctgat aaaatcattc gaaaggctgg ctcttcaatc 500

 ttccagcaca atgtagaagg ttggaaaatc aattcctctt tggtcctaga 550

 gataaggaag aacatacttc gtttcttaga tgcagaacga gatgtgtcag 600

 tggtcaagag cagttttaag cctggtgatg tcatacacta tgtgcttgac 650

 aggcgccgga cactaaacat ttctcatgat ctacatagcc tcctacctga 700

 agtttcacca atgaagaatc gcaggtttaa gacctgtgca gttgttggaa 750

 attctggcat tctgttagac agtgaatgtg gaaaggagat tgacagtcac 800

 aattttgtaa taaggtgtaa tctagctcct gtggtggagt ttgctgcaga 850

 tgtgggaact aaatcagatt ttattaccat gaatccatca gttgtacaaa 900

 gagcatttgg aggctttcga aatgagagtg acagagaaaa atttgtgcat 950

 agactttcca tgctgaatga cagtgtcctt tggattcctg ctttcatggt 1000

 caaaggagga gagaagcacg tggagtgggt taatgcatta atccttaaga 1050

 ataaactgaa agtgcgaact gcctatccgt cattgagact tattcatgct 1100

 gtcagaggtt actggctgac caacaaagtt cctatcaaaa gacccagcac 1150

 aggtcttctc atgtatacac ttgccacaag attctgtgat gaaattcacc 1200

 tgtatggatt ctggcccttc cctaaggatt taaatggaaa agcggtcaaa 1250

 tatcattatt atgatgactt aaaatatagg tacttttcca atgcaagccc 1300

 tcacagaatg ccattagaat tcaaaacatt aaatgtgcta cataatagag 1350

 gagctctaaa actgacaaca ggaaagtgtg taaagcaata aagcacattt 1400

 tgaaacaaac aatatgcact tcttttctga agatgcttcc gaagatttga 1450

 aaataggatc caaaacacgg ctgggtttca gcatccacca atgaactgaa 1500

 aggtgaataa aggacgttca tgagaaatcg actaccagct gatgaaatac 1550

 ctgcaaagtg ctctaaaaat taaatatttt gactttaagg gtcctagtaa 1600

 gtgccacttc cactaagaat acagtttgaa tgtataatca gtagtgttta 1650

 caagatccaa cagtgcactc atcattagtt aacaaagcaa atatgttcat 1700

 cactgtcagg ctgcccacag caacaccaag catattagaa gaggaacccc 1750

 aggaacgcaa ctcagacctt gggaaattaa accatccttg tcagcagaag 1800

 ccaagatgga agcagtttga gcaatgaaat ccgtaagatt aaacaactca 1850

 agtaaatgct tcagtcagga ctctgagtct gatcatgaat tttatgtttt 1900

 aatttatgtt ttttttttgt cttctggaat ctcttttggt ttggatattg 1950

 ggatgcttag aaatcctttc tgagatgcat atgagtgagg aaa 1993

<210> 1560
<211> 359
<212> PRT
<213> Homo sapien

<400> 1560
 Met Arg Ser Ile Arg Lys Arg Trp Thr Ile Cys Thr Ile Ser Leu
   1               5                  10                  15

 Leu Leu Ile Phe Tyr Lys Thr Lys Glu Ile Ala Arg Thr Glu Glu
                  20                  25                  30

 His Gln Glu Thr Gln Leu Ile Gly Asp Gly Glu Leu Ser Leu Ser
                  35                  40                  45

 Arg Ser Leu Val Asn Ser Ser Asp Lys Ile Ile Arg Lys Ala Gly
                  50                  55                  60

 Ser Ser Ile Phe Gln His Asn Val Glu Gly Trp Lys Ile Asn Ser
                  65                  70                  75

 Ser Leu Val Leu Glu Ile Arg Lys Asn Ile Leu Arg Phe Leu Asp
                  80                  85                  90

 Ala Glu Arg Asp Val Ser Val Val Lys Ser Ser Phe Lys Pro Gly
                  95                 100                 105

 Asp Val Ile His Tyr Val Leu Asp Arg Arg Arg Thr Leu Asn Ile
                 110                 115                 120

 Ser His Asp Leu His Ser Leu Leu Pro Glu Val Ser Pro Met Lys
                 125                 130                 135

 Asn Arg Arg Phe Lys Thr Cys Ala Val Val Gly Asn Ser Gly Ile
                 140                 145                 150

 Leu Leu Asp Ser Glu Cys Gly Lys Glu Ile Asp Ser His Asn Phe
                 155                 160                 165

 Val Ile Arg Cys Asn Leu Ala Pro Val Val Glu Phe Ala Ala Asp
                 170                 175                 180

 Val Gly Thr Lys Ser Asp Phe Ile Thr Met Asn Pro Ser Val Val
                 185                 190                 195

 Gln Arg Ala Phe Gly Gly Phe Arg Asn Glu Ser Asp Arg Glu Lys
                 200                 205                 210

 Phe Val His Arg Leu Ser Met Leu Asn Asp Ser Val Leu Trp Ile
                 215                 220                 225

 Pro Ala Phe Met Val Lys Gly Gly Glu Lys His Val Glu Trp Val
                 230                 235                 240

 Asn Ala Leu Ile Leu Lys Asn Lys Leu Lys Val Arg Thr Ala Tyr
                 245                 250                 255

 Pro Ser Leu Arg Leu Ile His Ala Val Arg Gly Tyr Trp Leu Thr
                 260                 265                 270

 Asn Lys Val Pro Ile Lys Arg Pro Ser Thr Gly Leu Leu Met Tyr
                 275                 280                 285

 Thr Leu Ala Thr Arg Phe Cys Asp Glu Ile His Leu Tyr Gly Phe
                 290                 295                 300

 Trp Pro Phe Pro Lys Asp Leu Asn Gly Lys Ala Val Lys Tyr His
                 305                 310                 315

 Tyr Tyr Asp Asp Leu Lys Tyr Arg Tyr Phe Ser Asn Ala Ser Pro
                 320                 325                 330

 His Arg Met Pro Leu Glu Phe Lys Thr Leu Asn Val Leu His Asn
                 335                 340                 345

 Arg Gly Ala Leu Lys Leu Thr Thr Gly Lys Cys Val Lys Gln
                 350                 355

<210> 1561
<211> 741
<212> DNA
<213> Homo sapien

<400> 1561
 gagaaatttt tcattttctt tcttgtttga ctgtatgcaa acatcaaact 50

 aagaatggca aagatgaatc tctcttccta tatattaata ctaacttttt 100

 ctttgttttc tcaaggtatt ttactttcag catccaagtc cataagaaat 150

 ttagatgatg acatggtatt taatacattc aggttgggga aaggctttca 200

 gaaggaagac actgcagaaa aatcagttat tgctccttcc ctggaacaat 250

 ataaaaatga tgagagcagt ttcatgaacg aagaggaaaa taaagtttca 300

 aagaacacag gctccaaaca taatttctta aatcatggtc tgccactcaa 350

 tctggctata aaaggatatc aagcactaaa aggatctgta gatttcccag 400

 ctgagaatgg agttcagaat actgaatcaa cacaagaaaa gagagaaatt 450

 ggggatgaag aaaactcagc taaatttcct ataggaagga gagattttga 500

 catgctcaga tgtatgctcg gaagagtcta ccgaccctgt tggcaagtct 550

 gatacctgtt ggtccacatc atcttttcag aagaaaataa aagcatttaa 600

 ttgccaatgg gaggagaagc ccatactgct actataactt gtgtatgtta 650

 aatgtctgtt ttaaaagaaa gtagtgttaa atgtatcagt aactgaaatg 700

 atatgctttc tctgtgcatt aaatttgtga aaattctgca t 741

<210> 1562
<211> 165
<212> PRT
<213> Homo sapien

<400> 1562
 Met Ala Lys Met Asn Leu Ser Ser Tyr Ile Leu Ile Leu Thr Phe
   1               5                  10                  15

 Ser Leu Phe Ser Gln Gly Ile Leu Leu Ser Ala Ser Lys Ser Ile
                  20                  25                  30

 Arg Asn Leu Asp Asp Asp Met Val Phe Asn Thr Phe Arg Leu Gly
                  35                  40                  45

 Lys Gly Phe Gln Lys Glu Asp Thr Ala Glu Lys Ser Val Ile Ala
                  50                  55                  60

 Pro Ser Leu Glu Gln Tyr Lys Asn Asp Glu Ser Ser Phe Met Asn
                  65                  70                  75

 Glu Glu Glu Asn Lys Val Ser Lys Asn Thr Gly Ser Lys His Asn
                  80                  85                  90

 Phe Leu Asn His Gly Leu Pro Leu Asn Leu Ala Ile Lys Gly Tyr
                  95                 100                 105

 Gln Ala Leu Lys Gly Ser Val Asp Phe Pro Ala Glu Asn Gly Val
                 110                 115                 120

 Gln Asn Thr Glu Ser Thr Gln Glu Lys Arg Glu Ile Gly Asp Glu
                 125                 130                 135

 Glu Asn Ser Ala Lys Phe Pro Ile Gly Arg Arg Asp Phe Asp Met
                 140                 145                 150

 Leu Arg Cys Met Leu Gly Arg Val Tyr Arg Pro Cys Trp Gln Val
                 155                 160                 165

<210> 1563
<211> 1953
<212> DNA
<213> Homo sapien

<400> 1563
 gcagaccttg cttcatgagc aagctcatct ctggaacaaa ctggcaaagc 50

 atctctgctg gtgttcatca gaacagacac catggcagag catgattacc 100

 atgaagacta tgggttcagc agtttcaatg acagcagcca ggaggagcat 150

 caagacttcc tgcagttcag caaggtcttt ctgccctgca tgtacctggt 200

 ggtgtttgtc tgtggtctgg tggggaactc tctggtgctg gtcatatcca 250

 tcttctacca taagttgcag agcctgacgg atgtgttcct ggtgaaccta 300

 cccctggctg acctggtgtt tgtctgcact ctgcccttct gggcctatgc 350

 aggcatccat gaatgggtgt ttggccaggt catgtgcaag agcctactgg 400

 gcatctacac tattaacttc tacacgtcca tgctcatcct cacctgcatc 450

 actgtggatc gtttcattgt agtggttaag gccaccaagg cctacaacca 500

 gcaagccaag aggatgacct ggggcaaggt caccagcttg ctcatctggg 550

 tgatatccct gctggtttcc ttgccccaaa ttatctatgg caatgtcttt 600

 aatctcgaca agctcatatg tggttaccat gacgaggcaa tttccactgt 650

 ggttcttgcc acccagatga cactggggtt cttcttgcca ctgctcacca 700

 tgattgtctg ctattcagtc ataatcaaaa cactgcttca tgctggaggc 750

 ttccagaagc acagatctct aaagatcatc ttcctggtga tggctgtgtt 800

 cctgctgacc cagatgccct tcaacctcat gaagttcatc cgcagcacac 850

 actgggaata ctatgccatg accagctttc actacaccat catggtgaca 900

 gaggccatcg catacctgag ggcctgcctt aaccctgtgc tctatgcctt 950

 tgtcagcctg aagtttcgaa agaacttctg gaaacttgtg aaggacattg 1000

 gttgcctccc ttaccttggg gtctcacatc aatggaaatc ttctgaggac 1050

 aattccaaga ctttttctgc ctcccacaat gtggaggcca ccagcatgtt 1100

 ccagttatag gccttgccag ggtttcgaga agctgctctg gaatttgcaa 1150

 gtcatggctg tgccctcttg atgtggtgag gcaggctttg tttatagctt 1200

 gcgcattctc atggagaagt tatcagacac tctggctggt ttggaatgct 1250

 tcttctcagg catgaacatg tactgttctc ttcttgaaca ctcatgctga 1300

 aagcccaagt agggggtcta aaatttttaa ggactttcct tcctccatct 1350

 ccaagaatgc tgaaaccaag ggggatgaca tgtgactcct atgatctcag 1400

 gttctccttg attgggactg gggctgaagg ttgaagaggt gagcacggcc 1450

 aacaaagctg ttgatggtag gtggcacact gggtgcccaa gctcagaagg 1500

 ctcttctgac tactgggcaa agagtgtaga tcagagcagc agtgaaaaca 1550

 agtgctggca ccaccaggca cctcacagaa atgagatcag gctctgcctc 1600

 accttggggc ttgacttttg tataggtaga tgttcagatt gctttgatta 1650

 atccagaata actagcacca gggactatga atgggcaaaa ctgaattata 1700

 agaggctgat aattccagtg gtccatggaa tgcttgaaaa atgtgcaaaa 1750

 cagcgtttaa gactgtaatg aatctaagca gcatttctga agtggactct 1800

 ttggtggctt tgcattttaa aaatgaaatt ttccaatgtc tgccacacaa 1850

 acgtatgtaa atgtatatac ccacacacat acacacatat gtcatatatt 1900

 actagcatat gagtttcata gctaagaaat aaaactgtta aagtctccaa 1950

 act 1953

<210> 1564
<211> 342
<212> PRT
<213> Homo sapien

<400> 1564
 Met Ala Glu His Asp Tyr His Glu Asp Tyr Gly Phe Ser Ser Phe
   1               5                  10                  15

 Asn Asp Ser Ser Gln Glu Glu His Gln Asp Phe Leu Gln Phe Ser
                  20                  25                  30

 Lys Val Phe Leu Pro Cys Met Tyr Leu Val Val Phe Val Cys Gly
                  35                  40                  45

 Leu Val Gly Asn Ser Leu Val Leu Val Ile Ser Ile Phe Tyr His
                  50                  55                  60

 Lys Leu Gln Ser Leu Thr Asp Val Phe Leu Val Asn Leu Pro Leu
                  65                  70                  75

 Ala Asp Leu Val Phe Val Cys Thr Leu Pro Phe Trp Ala Tyr Ala
                  80                  85                  90

 Gly Ile His Glu Trp Val Phe Gly Gln Val Met Cys Lys Ser Leu
                  95                 100                 105

 Leu Gly Ile Tyr Thr Ile Asn Phe Tyr Thr Ser Met Leu Ile Leu
                 110                 115                 120

 Thr Cys Ile Thr Val Asp Arg Phe Ile Val Val Val Lys Ala Thr
                 125                 130                 135

 Lys Ala Tyr Asn Gln Gln Ala Lys Arg Met Thr Trp Gly Lys Val
                 140                 145                 150

 Thr Ser Leu Leu Ile Trp Val Ile Ser Leu Leu Val Ser Leu Pro
                 155                 160                 165

 Gln Ile Ile Tyr Gly Asn Val Phe Asn Leu Asp Lys Leu Ile Cys
                 170                 175                 180

 Gly Tyr His Asp Glu Ala Ile Ser Thr Val Val Leu Ala Thr Gln
                 185                 190                 195

 Met Thr Leu Gly Phe Phe Leu Pro Leu Leu Thr Met Ile Val Cys
                 200                 205                 210

 Tyr Ser Val Ile Ile Lys Thr Leu Leu His Ala Gly Gly Phe Gln
                 215                 220                 225

 Lys His Arg Ser Leu Lys Ile Ile Phe Leu Val Met Ala Val Phe
                 230                 235                 240

 Leu Leu Thr Gln Met Pro Phe Asn Leu Met Lys Phe Ile Arg Ser
                 245                 250                 255

 Thr His Trp Glu Tyr Tyr Ala Met Thr Ser Phe His Tyr Thr Ile
                 260                 265                 270

 Met Val Thr Glu Ala Ile Ala Tyr Leu Arg Ala Cys Leu Asn Pro
                 275                 280                 285

 Val Leu Tyr Ala Phe Val Ser Leu Lys Phe Arg Lys Asn Phe Trp
                 290                 295                 300

 Lys Leu Val Lys Asp Ile Gly Cys Leu Pro Tyr Leu Gly Val Ser
                 305                 310                 315

 His Gln Trp Lys Ser Ser Glu Asp Asn Ser Lys Thr Phe Ser Ala
                 320                 325                 330

 Ser His Asn Val Glu Ala Thr Ser Met Phe Gln Leu
                 335                 340

<210> 1565
<211> 1386
<212> DNA
<213> Homo sapien

<400> 1565
 gccccatctc cttgggctgc ccgtgcttcg tgctttggac taccgcccag 50

 cagtgtcctg ccctctgcct gggcctcggt ccctcctgca cctgctgcct 100

 ggatccccgg cctgcctggg cctgggcctt ggttctcccc atgacaccac 150

 ctgaacgtct cttcctccca agggtgtgtg gcaccaccct acacctcctc 200

 cttctggggc tgctgctggt tctgctgcct ggggcccagg ggctccctgg 250

 tgttggcctc acaccttcag ctgcccagac tgcccgtcag caccccaaga 300

 tgcatcttgc ccacagcacc ctcaaacctg ctgctcacct cattggagac 350

 cccagcaagc agaactcact gctctggaga gcaaacacgg accgtgcctt 400

 cctccaggat ggtttctcct tgagcaacaa ttctctcctg gtccccacca 450

 gtggcatcta cttcgtctac tcccaggtgg tcttctctgg gaaagcctac 500

 tctcccaagg ccacctcctc cccactctac ctggcccatg aggtccagct 550

 cttctcctcc cagtacccct tccatgtgcc tctcctcagc tcccagaaga 600

 tggtgtatcc agggctgcag gaaccctggc tgcactcgat gtaccacggg 650

 gctgcgttcc agctcaccca gggagaccag ctatccaccc acacagatgg 700

 catcccccac ctagtcctca gccctagtac tgtcttcttt ggagccttcg 750

 ctctgtagaa cttggaaaaa tccagaaaga aaaaataatt gatttcaaga 800

 ccttctcccc attctgcctc cattctgacc atttcagggg tcgtcaccac 850

 ctctcctttg gccattccaa cagctcaagt cttccctgat caagtcaccg 900

 gagctttcaa agaaggaatt ctaggcatcc caggggacca cacctccctg 950

 aaccatccct gatgtctgtc tggctgagga tttcaagcct gcctaggaat 1000

 tcccagccca aagctgttgg tctgtcccac cagctaggtg gggcctagat 1050

 ccacacacag aggaagagca ggcacatgga ggagcttggg ggatgactag 1100

 aggcagggag gggactattt atgaaggcaa aaaaattaaa ttatttattt 1150

 atggaggatg gagagagggg aataatagaa gaacatccaa ggagaaacag 1200

 agacaggccc aagagatgaa gagtgagagg gcatgcgcac aaggctgacc 1250

 aagagagaaa gaagtaggca tgagggatca cagggcccca gaaggcaggg 1300

 aaaggctctg aaagccagct gccgaccaga gccccacacg gaggcatctg 1350

 caccctcgat gaagcccaat aaacctcttt tctctg 1386

<210> 1566
<211> 205
<212> PRT
<213> Homo sapien

<400> 1566
 Met Thr Pro Pro Glu Arg Leu Phe Leu Pro Arg Val Cys Gly Thr
   1               5                  10                  15

 Thr Leu His Leu Leu Leu Leu Gly Leu Leu Leu Val Leu Leu Pro
                  20                  25                  30

 Gly Ala Gln Gly Leu Pro Gly Val Gly Leu Thr Pro Ser Ala Ala
                  35                  40                  45

 Gln Thr Ala Arg Gln His Pro Lys Met His Leu Ala His Ser Thr
                  50                  55                  60

 Leu Lys Pro Ala Ala His Leu Ile Gly Asp Pro Ser Lys Gln Asn
                  65                  70                  75

 Ser Leu Leu Trp Arg Ala Asn Thr Asp Arg Ala Phe Leu Gln Asp
                  80                  85                  90

 Gly Phe Ser Leu Ser Asn Asn Ser Leu Leu Val Pro Thr Ser Gly
                  95                 100                 105

 Ile Tyr Phe Val Tyr Ser Gln Val Val Phe Ser Gly Lys Ala Tyr
                 110                 115                 120

 Ser Pro Lys Ala Thr Ser Ser Pro Leu Tyr Leu Ala His Glu Val
                 125                 130                 135

 Gln Leu Phe Ser Ser Gln Tyr Pro Phe His Val Pro Leu Leu Ser
                 140                 145                 150

 Ser Gln Lys Met Val Tyr Pro Gly Leu Gln Glu Pro Trp Leu His
                 155                 160                 165

 Ser Met Tyr His Gly Ala Ala Phe Gln Leu Thr Gln Gly Asp Gln
                 170                 175                 180

 Leu Ser Thr His Thr Asp Gly Ile Pro His Leu Val Leu Ser Pro
                 185                 190                 195

 Ser Thr Val Phe Phe Gly Ala Phe Ala Leu
                 200                 205

<210> 1567
<211> 2273
<212> DNA
<213> Homo sapien

<400> 1567
 caggactgcc tgagacaagc cacaagctga acagagaaag tggattgaac 50

 aaggacgcat ttccccagta catccacaac atgctgtcca catctcgttc 100

 tcggtttatc agaaatacca acgagagcgg tgaagaagtc accacctttt 150

 ttgattatga ttacggtgct ccctgtcata aatttgacgt gaagcaaatt 200

 ggggcccaac tcctgcctcc gctctactcg ctggtgttca tctttggttt 250

 tgtgggcaac atgctggtcg tcctcatctt aataaactgc aaaaagctga 300

 agtgcttgac tgacatttac ctgctcaacc tggccatctc tgatctgctt 350

 tttcttatta ctctcccatt gtgggctcac tctgctgcaa atgagtgggt 400

 ctttgggaat gcaatgtgca aattattcac agggctgtat cacatcggtt 450

 attttggcgg aatcttcttc atcatcctcc tgacaatcga tagatacctg 500

 gctattgtcc atgctgtgtt tgctttaaaa gccaggacgg tcacctttgg 550

 ggtggtgaca agtgtgatca cctggttggt ggctgtgttt gcttctgtcc 600

 caggaatcat ctttactaaa tgccagaaag aagattctgt ttatgtctgt 650

 ggcccttatt ttccacgagg atggaataat ttccacacaa taatgaggaa 700

 cattttgggg ctggtcctgc cgctgctcat catggtcatc tgctactcgg 750

 gaatcctgaa aaccctgctt cggtgtcgaa acgagaagaa gaggcatagg 800

 gcagtgagag tcatcttcac catcatgatt gtttactttc tcttctggac 850

 tccctataac attgtcattc tcctgaacac cttccaggaa ttcttcggcc 900

 tgagtaactg tgaaagcacc agtcaactgg accaagccac gcaggtgaca 950

 gagactcttg ggatgactca ctgctgcatc aatcccatca tctatgcctt 1000

 cgttggggag aagttcagaa gcctttttca catagctctt ggctgtagga 1050

 ttgccccact ccaaaaacca gtgtgtggag gtccaggagt gagaccagga 1100

 aagaatgtga aagtgactac acaaggactc ctcgatggtc gtggaaaagg 1150

 aaagtcaatt ggcagagccc ctgaagccag tcttcaggac aaagaaggag 1200

 cctagagaca gaaatgacag atctctgctt tggaaatcac acgtctggct 1250

 tcacagatgt gtgattcaca gtgtgaatct tggtgtctac gttaccaggc 1300

 aggaaggctg agaggagaga gactccagct gggttggaaa acagtatttt 1350

 ccaaactacc ttccagttcc tcatttttga atacaggcat agagttcaga 1400

 ctttttttaa atagtaaaaa taaaattaaa gctgaaaact gcaacttgta 1450

 aatgtggtaa agagttagtt tgagttgcta tcatgtcaaa cgtgaaaatg 1500

 ctgtattagt cacagagata attctagctt tgagcttaag aattttgagc 1550

 aggtggtatg tttgggagac tgctgagtca acccaatagt tgttgattgg 1600

 caggagttgg aagtgtgtga tctgtgggca cattagccta tgtgcatgca 1650

 gcatctaagt aatgatgtcg tttgaatcac agtatacgct ccatcgctgt 1700

 catctcagct ggatctccat tctctcaggc ttgctgccaa aagccttttg 1750

 tgttttgttt tgtatcatta tgaagtcatg cgtttaatca cattcgagtg 1800

 tttcagtgct tcgcagatgt ccttgatgct catattgttc cctaatttgc 1850

 cagtgggaac tcctaaatca aattggcttc taatcaaagc ttttaaaccc 1900

 tattggtaaa gaatggaagg tggagaagct ccctgaagta agcaaagact 1950

 ttcctcttag tcgagccaag ttaagaatgt tcttatgttg cccagtgtgt 2000

 ttctgatctg atgcaagcaa gaaacactgg gcttctagaa ccaggcaact 2050

 tgggaactag actcccaagc tggactatgg ctctactttc aggccacatg 2100

 gctaaagaag gtttcagaaa gaagtgggga cagagcagaa ctttcacctt 2150

 catatatttg tatgatccta atgaatgcat aaaatgttaa gttgatggtg 2200

 atgaaatgta aatactgttt ttaacaacta tgatttggaa aataaatcaa 2250

 tgctataact atgttgataa aag 2273

<210> 1568
<211> 374
<212> PRT
<213> Homo sapien

<400> 1568
 Met Leu Ser Thr Ser Arg Ser Arg Phe Ile Arg Asn Thr Asn Glu
   1               5                  10                  15

 Ser Gly Glu Glu Val Thr Thr Phe Phe Asp Tyr Asp Tyr Gly Ala
                  20                  25                  30

 Pro Cys His Lys Phe Asp Val Lys Gln Ile Gly Ala Gln Leu Leu
                  35                  40                  45

 Pro Pro Leu Tyr Ser Leu Val Phe Ile Phe Gly Phe Val Gly Asn
                  50                  55                  60

 Met Leu Val Val Leu Ile Leu Ile Asn Cys Lys Lys Leu Lys Cys
                  65                  70                  75

 Leu Thr Asp Ile Tyr Leu Leu Asn Leu Ala Ile Ser Asp Leu Leu
                  80                  85                  90

 Phe Leu Ile Thr Leu Pro Leu Trp Ala His Ser Ala Ala Asn Glu
                  95                 100                 105

 Trp Val Phe Gly Asn Ala Met Cys Lys Leu Phe Thr Gly Leu Tyr
                 110                 115                 120

 His Ile Gly Tyr Phe Gly Gly Ile Phe Phe Ile Ile Leu Leu Thr
                 125                 130                 135

 Ile Asp Arg Tyr Leu Ala Ile Val His Ala Val Phe Ala Leu Lys
                 140                 145                 150

 Ala Arg Thr Val Thr Phe Gly Val Val Thr Ser Val Ile Thr Trp
                 155                 160                 165

 Leu Val Ala Val Phe Ala Ser Val Pro Gly Ile Ile Phe Thr Lys
                 170                 175                 180

 Cys Gln Lys Glu Asp Ser Val Tyr Val Cys Gly Pro Tyr Phe Pro
                 185                 190                 195

 Arg Gly Trp Asn Asn Phe His Thr Ile Met Arg Asn Ile Leu Gly
                 200                 205                 210

 Leu Val Leu Pro Leu Leu Ile Met Val Ile Cys Tyr Ser Gly Ile
                 215                 220                 225

 Leu Lys Thr Leu Leu Arg Cys Arg Asn Glu Lys Lys Arg His Arg
                 230                 235                 240

 Ala Val Arg Val Ile Phe Thr Ile Met Ile Val Tyr Phe Leu Phe
                 245                 250                 255

 Trp Thr Pro Tyr Asn Ile Val Ile Leu Leu Asn Thr Phe Gln Glu
                 260                 265                 270

 Phe Phe Gly Leu Ser Asn Cys Glu Ser Thr Ser Gln Leu Asp Gln
                 275                 280                 285

 Ala Thr Gln Val Thr Glu Thr Leu Gly Met Thr His Cys Cys Ile
                 290                 295                 300

 Asn Pro Ile Ile Tyr Ala Phe Val Gly Glu Lys Phe Arg Ser Leu
                 305                 310                 315

 Phe His Ile Ala Leu Gly Cys Arg Ile Ala Pro Leu Gln Lys Pro
                 320                 325                 330

 Val Cys Gly Gly Pro Gly Val Arg Pro Gly Lys Asn Val Lys Val
                 335                 340                 345

 Thr Thr Gln Gly Leu Leu Asp Gly Arg Gly Lys Gly Lys Ser Ile
                 350                 355                 360

 Gly Arg Ala Pro Glu Ala Ser Leu Gln Asp Lys Glu Gly Ala
                 365                 370

<210> 1569
<211> 859
<212> DNA
<213> Homo sapien

<400> 1569
 tggaaagggc tgtcacccgg cttggcccct tccacaccca actggggcaa 50

 gcctgacccg gcgacaggag gcatgagggg cccccggccg aaatgacagt 100

 gctggcgcca gcctggagcc caacaaccta tctcctcctg ctgctgctgc 150

 tgagctcggg actcagtggg acccaggact gctccttcca acacagcccc 200

 atctcctccg acttcgctgt caaaatccgt gagctgtctg actacctgct 250

 tcaagattac ccagtcaccg tggcctccaa cctgcaggac gaggagctct 300

 gcggggcgct ctggcggctg gtcctggcac agcgctggat ggagcggctc 350

 aagactgtcg ctgggtccaa gatgcaaggc ttgctggagc gcgtgaacac 400

 ggagatacac tttgtcacca aatgtgcctt tcagcccccc cccagctgtc 450

 ttcgcttcgt ccagaccaac atctcccgcc tcctgcagga gacctccgag 500

 cagctggtgg cgctgaagcc ctggatcact cgccagaact tctcccggtg 550

 cctggagctg cagtgtcagc ccgactcctc aaccctgcca cccccatgga 600

 gtccccggcc cctggaggcc acagccccga cagccccgca gccccctctg 650

 ctcctcctac tgctgctgcc cgtgggcctc ctgctgctgg ccgctgcctg 700

 gtgcctgcac tggcagagga cgcggcggag gacaccccgc cctggggagc 750

 aggtgccccc cgtccccagt ccccaggacc tgctgcttgt ggagcactga 800

 cctggccaag gcctcatcct ggggaggata cgtaggcaca cagaggggag 850

 tcaccagcc 859

<210> 1570
<211> 235
<212> PRT
<213> Homo sapien

<400> 1570
 Met Thr Val Leu Ala Pro Ala Trp Ser Pro Thr Thr Tyr Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Leu Ser Ser Gly Leu Ser Gly Thr Gln Asp Cys
                  20                  25                  30

 Ser Phe Gln His Ser Pro Ile Ser Ser Asp Phe Ala Val Lys Ile
                  35                  40                  45

 Arg Glu Leu Ser Asp Tyr Leu Leu Gln Asp Tyr Pro Val Thr Val
                  50                  55                  60

 Ala Ser Asn Leu Gln Asp Glu Glu Leu Cys Gly Ala Leu Trp Arg
                  65                  70                  75

 Leu Val Leu Ala Gln Arg Trp Met Glu Arg Leu Lys Thr Val Ala
                  80                  85                  90

 Gly Ser Lys Met Gln Gly Leu Leu Glu Arg Val Asn Thr Glu Ile
                  95                 100                 105

 His Phe Val Thr Lys Cys Ala Phe Gln Pro Pro Pro Ser Cys Leu
                 110                 115                 120

 Arg Phe Val Gln Thr Asn Ile Ser Arg Leu Leu Gln Glu Thr Ser
                 125                 130                 135

 Glu Gln Leu Val Ala Leu Lys Pro Trp Ile Thr Arg Gln Asn Phe
                 140                 145                 150

 Ser Arg Cys Leu Glu Leu Gln Cys Gln Pro Asp Ser Ser Thr Leu
                 155                 160                 165

 Pro Pro Pro Trp Ser Pro Arg Pro Leu Glu Ala Thr Ala Pro Thr
                 170                 175                 180

 Ala Pro Gln Pro Pro Leu Leu Leu Leu Leu Leu Leu Pro Val Gly
                 185                 190                 195

 Leu Leu Leu Leu Ala Ala Ala Trp Cys Leu His Trp Gln Arg Thr
                 200                 205                 210

 Arg Arg Arg Thr Pro Arg Pro Gly Glu Gln Val Pro Pro Val Pro
                 215                 220                 225

 Ser Pro Gln Asp Leu Leu Leu Val Glu His
                 230                 235

<210> 1571
<211> 3655
<212> DNA
<213> Homo sapien

<400> 1571
 cttcagatag attatatctg gagtgaagga tcctgccacc tacgtatctg 50

 gcatagtatt ctgtgtagtg ggatgagcag agaacaaaaa caaaataatc 100

 cagtgagaaa agcccgtaaa taaaccttca gaccagagat ctattctcca 150

 gcttatttta agctcaactt aaaaagaaga actgttctct gattcttttc 200

 gccttcaata cacttaatga tttaactcca ccctccttca aaagaaacag 250

 catttcctac ttttatactg tctatatgat tgatttgcac agctcatctg 300

 gccagaagag ctgagacatc cgttccccta caagaaactc tccccgggtg 350

 gaacaagatg gattatcaag tgtcaagtcc aatctatgac atcaattatt 400

 atacatcgga gccctgccaa aaaatcaatg tgaagcaaat cgcagcccgc 450

 ctcctgcctc cgctctactc actggtgttc atctttggtt ttgtgggcaa 500

 catgctggtc atcctcatcc tgataaactg caaaaggctg aagagcatga 550

 ctgacatcta cctgctcaac ctggccatct ctgacctgtt tttccttctt 600

 actgtcccct tctgggctca ctatgctgcc gcccagtggg actttggaaa 650

 tacaatgtgt caactcttga cagggctcta ttttataggc ttcttctctg 700

 gaatcttctt catcatcctc ctgacaatcg ataggtacct ggctgtcgtc 750

 catgctgtgt ttgctttaaa agccaggacg gtcacctttg gggtggtgac 800

 aagtgtgatc acttgggtgg tggctgtgtt tgcgtctctc ccaggaatca 850

 tctttaccag atctcaaaaa gaaggtcttc attacacctg cagctctcat 900

 tttccataca gtcagtatca attctggaag aatttccaga cattaaagat 950

 agtcatcttg gggctggtcc tgccgctgct tgtcatggtc atctgctact 1000

 cgggaatcct aaaaactctg cttcggtgtc gaaatgagaa gaagaggcac 1050

 agggctgtga ggcttatctt caccatcatg attgtttatt ttctcttctg 1100

 ggctccctac aacattgtcc ttctcctgaa caccttccag gaattctttg 1150

 gcctgaataa ttgcagtagc tctaacaggt tggaccaagc tatgcaggtg 1200

 acagagactc ttgggatgac gcactgctgc atcaacccca tcatctatgc 1250

 ctttgtcggg gagaagttca gaaactacct cttagtcttc ttccaaaagc 1300

 acattgccaa acgcttctgc aaatgctgtt ctattttcca gcaagaggct 1350

 cccgagcgag caagctcagt ttacacccga tccactgggg agcaggaaat 1400

 atctgtgggc ttgtgacacg gactcaagtg ggctggtgac ccagtcagag 1450

 ttgtgcacat ggcttagttt tcatacacag cctgggctgg gggtggggtg 1500

 ggagaggtct tttttaaaag gaagttactg ttatagaggg tctaagattc 1550

 atccatttat ttggcatctg tttaaagtag attagatctt ttaagcccat 1600

 caattataga aagccaaatc aaaatatgtt gatgaaaaat agcaaccttt 1650

 ttatctcccc ttcacatgca tcaagttatt gacaaactct cccttcactc 1700

 cgaaagttcc ttatgtatat ttaaaagaaa gcctcagaga attgctgatt 1750

 cttgagttta gtgatctgaa cagaaatacc aaaattattt cagaaatgta 1800

 caacttttta cctagtacaa ggcaacatat aggttgtaaa tgtgtttaaa 1850

 acaggtcttt gtcttgctat ggggagaaaa gacatgaata tgattagtaa 1900

 agaaatgaca cttttcatgt gtgatttccc ctccaaggta tggttaataa 1950

 gtttcactga cttagaacca ggcgagagac ttgtggcctg ggagagctgg 2000

 ggaagcttct taaatgagaa ggaatttgag ttggatcatc tattgctggc 2050

 aaagacagaa gcctcactgc aagcactgca tgggcaagct tggctgtaga 2100

 aggagacaga gctggttggg aagacatggg gaggaaggac aaggctagat 2150

 catgaagaac cttgacggca ttgctccgtc taagtcatga gctgagcagg 2200

 gagatcctgg ttggtgttgc agaaggttta ctctgtggcc aaaggagggt 2250

 caggaaggat gagcatttag ggcaaggaga ccaccaacag ccctcaggtc 2300

 agggtgagga tggcctctgc taagctcaag gcgtgaggat gggaaggagg 2350

 gaggtattcg taaggatggg aaggagggag gtattcgtgc agcatatgag 2400

 gatgcagagt cagcagaact ggggtggatt tggtttggaa gtgagggtca 2450

 gagaggagtc agagagaatc cctagtcttc aagcagattg gagaaaccct 2500

 tgaaaagaca tcaagcacag aaggaggagg aggaggttta ggtcaagaag 2550

 aagatggatt ggtgtaaaag gatgggtctg gtttgcagag cttgaacaca 2600

 gtctcaccca gactccaggc tgtctttcac tgaatgcttc tgacttcata 2650

 gatttccttc ccatcccagc tgaaatactg aggggtctcc aggaggagac 2700

 tagatttatg aatacacgag gtatgaggtc taggaacata cttcagctca 2750

 cacatgagat ctaggtgagg attgattacc tagtagtcat ttcatgggtt 2800

 gttgggagga ttctatgagg caaccacagg cagcatttag cacatactac 2850

 acattcaata agcatcaaac tcttagttac tcattcaggg atagcactga 2900

 gcaaagcatt gagcaaaggg gtcccatata ggtgagggaa gcctgaaaaa 2950

 ctaagatgct gcctgcccag tgcacacaag tgtaggtatc attttctgca 3000

 tttaaccgtc aataggcaaa ggggggaagg gacatattca tttggaaata 3050

 agctgccttg agccttaaaa cccacaaaag tacaatttac cagcctccgt 3100

 atttcagact gaatgggggt ggggggggcg ccttaggtac ttattccaga 3150

 tgccttctcc agacaaacca gaagcaacag aaaaaatcgt ctctccctcc 3200

 ctttgaaatg aatatacccc ttagtgtttg ggtatattca tttcaaaggg 3250

 agagagagag gtttttttct gttctttctc atatgattgt gcacatactt 3300

 gagactgttt tgaatttggg ggatggctaa aaccatcata gtacaggtaa 3350

 ggtgagggaa tagtaagtgg tgagaactac tcagggaatg aaggtgtcag 3400

 aataataaga ggtgctactg actttctcag cctctgaata tgaacggtga 3450

 gcattgtggc tgtcagcagg aagcaacgaa gggaaatgtc tttccttttg 3500

 ctcttaagtt gtggagagtg caacagtagc ataggaccct accctctggg 3550

 ccaagtcaaa gacattctga catcttagta tttgcatatt cttatgtatg 3600

 tgaaagttac aaattgcttg aaagaaaata tgcatctaat aaaaaacacc 3650

 ttcta 3655

<210> 1572
<211> 352
<212> PRT
<213> Homo sapien

<400> 1572
 Met Asp Tyr Gln Val Ser Ser Pro Ile Tyr Asp Ile Asn Tyr Tyr
   1               5                  10                  15

 Thr Ser Glu Pro Cys Gln Lys Ile Asn Val Lys Gln Ile Ala Ala
                  20                  25                  30

 Arg Leu Leu Pro Pro Leu Tyr Ser Leu Val Phe Ile Phe Gly Phe
                  35                  40                  45

 Val Gly Asn Met Leu Val Ile Leu Ile Leu Ile Asn Cys Lys Arg
                  50                  55                  60

 Leu Lys Ser Met Thr Asp Ile Tyr Leu Leu Asn Leu Ala Ile Ser
                  65                  70                  75

 Asp Leu Phe Phe Leu Leu Thr Val Pro Phe Trp Ala His Tyr Ala
                  80                  85                  90

 Ala Ala Gln Trp Asp Phe Gly Asn Thr Met Cys Gln Leu Leu Thr
                  95                 100                 105

 Gly Leu Tyr Phe Ile Gly Phe Phe Ser Gly Ile Phe Phe Ile Ile
                 110                 115                 120

 Leu Leu Thr Ile Asp Arg Tyr Leu Ala Val Val His Ala Val Phe
                 125                 130                 135

 Ala Leu Lys Ala Arg Thr Val Thr Phe Gly Val Val Thr Ser Val
                 140                 145                 150

 Ile Thr Trp Val Val Ala Val Phe Ala Ser Leu Pro Gly Ile Ile
                 155                 160                 165

 Phe Thr Arg Ser Gln Lys Glu Gly Leu His Tyr Thr Cys Ser Ser
                 170                 175                 180

 His Phe Pro Tyr Ser Gln Tyr Gln Phe Trp Lys Asn Phe Gln Thr
                 185                 190                 195

 Leu Lys Ile Val Ile Leu Gly Leu Val Leu Pro Leu Leu Val Met
                 200                 205                 210

 Val Ile Cys Tyr Ser Gly Ile Leu Lys Thr Leu Leu Arg Cys Arg
                 215                 220                 225

 Asn Glu Lys Lys Arg His Arg Ala Val Arg Leu Ile Phe Thr Ile
                 230                 235                 240

 Met Ile Val Tyr Phe Leu Phe Trp Ala Pro Tyr Asn Ile Val Leu
                 245                 250                 255

 Leu Leu Asn Thr Phe Gln Glu Phe Phe Gly Leu Asn Asn Cys Ser
                 260                 265                 270

 Ser Ser Asn Arg Leu Asp Gln Ala Met Gln Val Thr Glu Thr Leu
                 275                 280                 285

 Gly Met Thr His Cys Cys Ile Asn Pro Ile Ile Tyr Ala Phe Val
                 290                 295                 300

 Gly Glu Lys Phe Arg Asn Tyr Leu Leu Val Phe Phe Gln Lys His
                 305                 310                 315

 Ile Ala Lys Arg Phe Cys Lys Cys Cys Ser Ile Phe Gln Gln Glu
                 320                 325                 330

 Ala Pro Glu Arg Ala Ser Ser Val Tyr Thr Arg Ser Thr Gly Glu
                 335                 340                 345

 Gln Glu Ile Ser Val Gly Leu
                 350

<210> 1573
<211> 4040
<212> DNA
<213> Homo sapien

<400> 1573
 tgcagagcac agagaaagga catctgcgag gaaagttccc tgatggctgt 50

 caacaaagtg ccacgtctct atggctgtga acgctgagca cacgatttta 100

 tcgcgcctat catatcttgg tgcataaacg cacctcacct cggtcaaccc 150

 ttgctccgtc ttatgagaca ggctttatta tccgcatttt atatgagggg 200

 aaactgacgg tggagagaga attatcttgc tcaaggcgac acagcagagc 250

 ccacaggtgg cagaatccca cccgagcccg cttcgacccg cggggtggaa 300

 accacgggcg cccgcccggc tgcgcttcca gagctgaact gagaagcgag 350

 tcctctccgc cctgcggcca ccgcccagcc ccgacccccg ccccggcccg 400

 atcctcactc gccgccagct ccccgcgccc accccggagt tggtggcgca 450

 gaggcgggag gcggaggcgg gagggcgggc gctggcaccg ggaacgcccg 500

 agcgccggca gagagcgcgg agagcgcgac acgtgcggcc cagagcaccg 550

 gggccacccg gtccccgcag gcccgggacc gcgcccgctg gcaggcgaca 600

 cgtggaagaa tacggagttc tataccagag ttgattgttg atggcacata 650

 cttttagagg atgctcattg gcatttatgt ttataatcac gtggctgttg 700

 attaaagcaa aaatagatgc gtgcaagaga ggcgatgtga ctgtgaagcc 750

 ttcccatgta attttacttg gatccactgt caatattaca tgctctttga 800

 agcccagaca aggctgcttt cactattcca gacgtaacaa gttaatcctg 850

 tacaagtttg acagaagaat caattttcac catggccact ccctcaattc 900

 tcaagtcaca ggtcttcccc ttggtacaac cttgtttgtc tgcaaactgg 950

 cctgtatcaa tagtgatgaa attcaaatat gtggagcaga gatcttcgtt 1000

 ggtgttgctc cagaacagcc tcaaaattta tcctgcatac agaagggaga 1050

 acaggggact gtggcctgca cctgggaaag aggacgagac acccacttat 1100

 acactgagta tactctacag ctaagtggac caaaaaattt aacctggcag 1150

 aagcaatgta aagacattta ttgtgactat ttggactttg gaatcaacct 1200

 cacccctgaa tcacctgaat ccaatttcac agccaaggtt actgctgtca 1250

 atagtcttgg aagctcctct tcacttccat ccacattcac attcttggac 1300

 atagtgaggc ctcttcctcc gtgggacatt agaatcaaat ttcaaaaggc 1350

 ttctgtgagc agatgtaccc tttattggag agatgaggga ctggtactgc 1400

 ttaatcgact cagatatcgg cccagtaaca gcaggctctg gaatatggtt 1450

 aatgttacaa aggccaaagg aagacatgat ttgctggatc tgaaaccatt 1500

 tacagaatat gaatttcaga tttcctctaa gctacatctt tataagggaa 1550

 gttggagtga ttggagtgaa tcattgagag cacaaacacc agaagaagag 1600

 cctactggga tgttagatgt ctggtacatg aaacggcaca ttgactacag 1650

 tagacaacag atttctcttt tctggaagaa tctgagtgtc tcagaggcaa 1700

 gaggaaaaat tctccactat caggtgacct tgcaggagct gacaggaggg 1750

 aaagccatga cacagaacat cacaggacac acctcctgga ccacagtcat 1800

 tcctagaacc ggaaattggg ctgtggctgt gtctgcagca aattcaaaag 1850

 gcagttctct gcccactcgt attaacataa tgaacctgtg tgaggcaggg 1900

 ttgctggctc ctcgccaggt ctctgcaaac tcagagggca tggacaacat 1950

 tctggtgact tggcagcctc ccaggaaaga tccctctgct gttcaggagt 2000

 acgtggtgga atggagagag ctccatccag ggggtgacac acaggtccct 2050

 ctaaactggc tacggagtcg accctacaat gtgtctgctc tgatttcaga 2100

 gaacataaaa tcctacatct gttatgaaat ccgtgtgtat gcactctcag 2150

 gggatcaagg aggatgcagc tccatcctgg gtaactctaa gcacaaagca 2200

 ccactgagtg gcccccacat taatgccatc acagaggaaa aggggagcat 2250

 tttaatttca tggaacagca ttccagtcca ggagcaaatg ggctgcctcc 2300

 tccattatag gatatactgg aaggaacggg actccaactc ccagcctcag 2350

 ctctgtgaaa ttccctacag agtctcccaa aattcacatc caataaacag 2400

 cctgcagccc cgagtgacat atgtcctgtg gatgacagct ctgacagctg 2450

 ctggtgaaag ttcccacgga aatgagaggg aattttgtct gcaaggtaaa 2500

 gccaattgga tggcgtttgt ggcaccaagc atttgcattg ctatcatcat 2550

 ggtgggcatt ttctcaacgc attacttcca gcaaaaggtg tttgttctcc 2600

 tagcagccct cagacctcag tggtgtagca gagaaattcc agatccagca 2650

 aatagcactt gcgctaagaa atatcccatt gcagaggaga agacacagct 2700

 gcccttggac aggctcctga tagactggcc cacgcctgaa gatcctgaac 2750

 cgctggtcat cagtgaagtc cttcatcaag tgaccccagt tttcagacat 2800

 cccccctgct ccaactggcc acaaagggaa aaaggaatcc aaggtcatca 2850

 ggcctctgag aaagacatga tgcacagtgc ctcaagccca ccacctccaa 2900

 gagctctcca agctgagagc agacaactgg tggatctgta caaggtgctg 2950

 gagagcaggg gctccgaccc aaagcccgaa aacccagcct gtccctggac 3000

 ggtgctccca gcaggtgacc ttcccaccca tgatggctac ttaccctcca 3050

 acatagatga cctcccctca catgaggcac ctctcgctga ctctctggaa 3100

 gaactggagc ctcagcacat ctccctttct gttttcccct caagttctct 3150

 tcacccactc accttctcct gtggtgataa gctgactctg gatcagttaa 3200

 agatgaggtg tgactccctc atgctctgag tggtgaggct tcaagcctta 3250

 aagtcagtgt gccctcaacc agcacagcct gccccaattc ccccagcccc 3300

 tgctccagca gctgtcatct ctgggtgcca ccatcggtct ggctgcagct 3350

 agaggacagg caagccagct ctgggggagt cttaggaact gggagttggt 3400

 cttcactcag atgcctcatc ttgcctttcc cagggcctta aaattacatc 3450

 cttcactgtg tggacctaga gactccaact tgaattccta gtaactttct 3500

 tggtatgctg gccagaaagg gaaatgagga ggagagtaga aaccacagct 3550

 cttagtagta atggcataca gtctagagga ccattcatgc aatgactatt 3600

 tctaaagcac ctgctacaca gcaggctgta cacagcagat cagtactgtt 3650

 caacagaact tcctgagatg atggaaatgt tctacctctg cactcactgt 3700

 ccagtacatt agacactagg cacattggct gttaatcact tggaatgtgt 3750

 ttagcttgac tgaggaatta aattttgatt gtaaatttaa atcgccacac 3800

 atggctagtg gctactgtat tggagtgcac agctctagat ggctcctaga 3850

 ttattgagag ccttcaaaac aaatcaacct agttctatag atgaagacat 3900

 aaaagacact ggtaaacacc aaggtaaaag ggcccccaag gtggtcatga 3950

 ctggtctcat ttgcagaagt ctaagaatgt acctttttct ggccgggcgt 4000

 ggtagctcat gcctgtaatc ccagcacttt gggaggctga 4040

<210> 1574
<211> 862
<212> PRT
<213> Homo sapien

<400> 1574
 Met Ala His Thr Phe Arg Gly Cys Ser Leu Ala Phe Met Phe Ile
   1               5                  10                  15

 Ile Thr Trp Leu Leu Ile Lys Ala Lys Ile Asp Ala Cys Lys Arg
                  20                  25                  30

 Gly Asp Val Thr Val Lys Pro Ser His Val Ile Leu Leu Gly Ser
                  35                  40                  45

 Thr Val Asn Ile Thr Cys Ser Leu Lys Pro Arg Gln Gly Cys Phe
                  50                  55                  60

 His Tyr Ser Arg Arg Asn Lys Leu Ile Leu Tyr Lys Phe Asp Arg
                  65                  70                  75

 Arg Ile Asn Phe His His Gly His Ser Leu Asn Ser Gln Val Thr
                  80                  85                  90

 Gly Leu Pro Leu Gly Thr Thr Leu Phe Val Cys Lys Leu Ala Cys
                  95                 100                 105

 Ile Asn Ser Asp Glu Ile Gln Ile Cys Gly Ala Glu Ile Phe Val
                 110                 115                 120

 Gly Val Ala Pro Glu Gln Pro Gln Asn Leu Ser Cys Ile Gln Lys
                 125                 130                 135

 Gly Glu Gln Gly Thr Val Ala Cys Thr Trp Glu Arg Gly Arg Asp
                 140                 145                 150

 Thr His Leu Tyr Thr Glu Tyr Thr Leu Gln Leu Ser Gly Pro Lys
                 155                 160                 165

 Asn Leu Thr Trp Gln Lys Gln Cys Lys Asp Ile Tyr Cys Asp Tyr
                 170                 175                 180

 Leu Asp Phe Gly Ile Asn Leu Thr Pro Glu Ser Pro Glu Ser Asn
                 185                 190                 195

 Phe Thr Ala Lys Val Thr Ala Val Asn Ser Leu Gly Ser Ser Ser
                 200                 205                 210

 Ser Leu Pro Ser Thr Phe Thr Phe Leu Asp Ile Val Arg Pro Leu
                 215                 220                 225

 Pro Pro Trp Asp Ile Arg Ile Lys Phe Gln Lys Ala Ser Val Ser
                 230                 235                 240

 Arg Cys Thr Leu Tyr Trp Arg Asp Glu Gly Leu Val Leu Leu Asn
                 245                 250                 255

 Arg Leu Arg Tyr Arg Pro Ser Asn Ser Arg Leu Trp Asn Met Val
                 260                 265                 270

 Asn Val Thr Lys Ala Lys Gly Arg His Asp Leu Leu Asp Leu Lys
                 275                 280                 285

 Pro Phe Thr Glu Tyr Glu Phe Gln Ile Ser Ser Lys Leu His Leu
                 290                 295                 300

 Tyr Lys Gly Ser Trp Ser Asp Trp Ser Glu Ser Leu Arg Ala Gln
                 305                 310                 315

 Thr Pro Glu Glu Glu Pro Thr Gly Met Leu Asp Val Trp Tyr Met
                 320                 325                 330

 Lys Arg His Ile Asp Tyr Ser Arg Gln Gln Ile Ser Leu Phe Trp
                 335                 340                 345

 Lys Asn Leu Ser Val Ser Glu Ala Arg Gly Lys Ile Leu His Tyr
                 350                 355                 360

 Gln Val Thr Leu Gln Glu Leu Thr Gly Gly Lys Ala Met Thr Gln
                 365                 370                 375

 Asn Ile Thr Gly His Thr Ser Trp Thr Thr Val Ile Pro Arg Thr
                 380                 385                 390

 Gly Asn Trp Ala Val Ala Val Ser Ala Ala Asn Ser Lys Gly Ser
                 395                 400                 405

 Ser Leu Pro Thr Arg Ile Asn Ile Met Asn Leu Cys Glu Ala Gly
                 410                 415                 420

 Leu Leu Ala Pro Arg Gln Val Ser Ala Asn Ser Glu Gly Met Asp
                 425                 430                 435

 Asn Ile Leu Val Thr Trp Gln Pro Pro Arg Lys Asp Pro Ser Ala
                 440                 445                 450

 Val Gln Glu Tyr Val Val Glu Trp Arg Glu Leu His Pro Gly Gly
                 455                 460                 465

 Asp Thr Gln Val Pro Leu Asn Trp Leu Arg Ser Arg Pro Tyr Asn
                 470                 475                 480

 Val Ser Ala Leu Ile Ser Glu Asn Ile Lys Ser Tyr Ile Cys Tyr
                 485                 490                 495

 Glu Ile Arg Val Tyr Ala Leu Ser Gly Asp Gln Gly Gly Cys Ser
                 500                 505                 510

 Ser Ile Leu Gly Asn Ser Lys His Lys Ala Pro Leu Ser Gly Pro
                 515                 520                 525

 His Ile Asn Ala Ile Thr Glu Glu Lys Gly Ser Ile Leu Ile Ser
                 530                 535                 540

 Trp Asn Ser Ile Pro Val Gln Glu Gln Met Gly Cys Leu Leu His
                 545                 550                 555

 Tyr Arg Ile Tyr Trp Lys Glu Arg Asp Ser Asn Ser Gln Pro Gln
                 560                 565                 570

 Leu Cys Glu Ile Pro Tyr Arg Val Ser Gln Asn Ser His Pro Ile
                 575                 580                 585

 Asn Ser Leu Gln Pro Arg Val Thr Tyr Val Leu Trp Met Thr Ala
                 590                 595                 600

 Leu Thr Ala Ala Gly Glu Ser Ser His Gly Asn Glu Arg Glu Phe
                 605                 610                 615

 Cys Leu Gln Gly Lys Ala Asn Trp Met Ala Phe Val Ala Pro Ser
                 620                 625                 630

 Ile Cys Ile Ala Ile Ile Met Val Gly Ile Phe Ser Thr His Tyr
                 635                 640                 645

 Phe Gln Gln Lys Val Phe Val Leu Leu Ala Ala Leu Arg Pro Gln
                 650                 655                 660

 Trp Cys Ser Arg Glu Ile Pro Asp Pro Ala Asn Ser Thr Cys Ala
                 665                 670                 675

 Lys Lys Tyr Pro Ile Ala Glu Glu Lys Thr Gln Leu Pro Leu Asp
                 680                 685                 690

 Arg Leu Leu Ile Asp Trp Pro Thr Pro Glu Asp Pro Glu Pro Leu
                 695                 700                 705

 Val Ile Ser Glu Val Leu His Gln Val Thr Pro Val Phe Arg His
                 710                 715                 720

 Pro Pro Cys Ser Asn Trp Pro Gln Arg Glu Lys Gly Ile Gln Gly
                 725                 730                 735

 His Gln Ala Ser Glu Lys Asp Met Met His Ser Ala Ser Ser Pro
                 740                 745                 750

 Pro Pro Pro Arg Ala Leu Gln Ala Glu Ser Arg Gln Leu Val Asp
                 755                 760                 765

 Leu Tyr Lys Val Leu Glu Ser Arg Gly Ser Asp Pro Lys Pro Glu
                 770                 775                 780

 Asn Pro Ala Cys Pro Trp Thr Val Leu Pro Ala Gly Asp Leu Pro
                 785                 790                 795

 Thr His Asp Gly Tyr Leu Pro Ser Asn Ile Asp Asp Leu Pro Ser
                 800                 805                 810

 His Glu Ala Pro Leu Ala Asp Ser Leu Glu Glu Leu Glu Pro Gln
                 815                 820                 825

 His Ile Ser Leu Ser Val Phe Pro Ser Ser Ser Leu His Pro Leu
                 830                 835                 840

 Thr Phe Ser Cys Gly Asp Lys Leu Thr Leu Asp Gln Leu Lys Met
                 845                 850                 855

 Arg Cys Asp Ser Leu Met Leu
                 860

<210> 1575
<211> 1365
<212> DNA
<213> Homo sapien

<400> 1575
 gtggagcccg ggagttccag ggcttgggaa ggggaaggaa acctctctga 50

 aatctgacac ctgctctccc ggcaaggaaa cttcgcaggc tgaccgacca 100

 agaccatcac tatgaccgat ggagactatg attatctgat caaactcctg 150

 gccctcgggg attcaggggt ggggaagaca acatttcttt atagatacac 200

 agataataaa ttcaatccca aattcatcac tacagtagga atagactttc 250

 gggaaaaacg tgtggtttat aatgcacaag gaccgaatgg atcttcaggg 300

 aaagcattta aagtgcatct tcagctttgg gacactgcgg gacaagagcg 350

 gttccggagt ctcaccactg catttttcag agacgccatg ggcttcttat 400

 taatgtttga cctcaccagt caacagagct tcttaaatgt cagaaactgg 450

 atgagccaac tgcaagcaaa tgcttattgt gaaaatccag atatagtatt 500

 aattggcaac aaggcagacc taccagatca gagggaagtc aatgaacggc 550

 aagctcggga actggctgac aaatatggca taccatattt tgaaacaagt 600

 gcagcaactg gacagaatgt ggagaaagct gtagaaaccc ttttggactt 650

 aatcatgaag cgaatggaac agtgtgtgga gaagacacaa atccctgata 700

 ctgtcaatgg tggaaattct ggaaacttgg atggggaaaa gccaccagag 750

 aagaaatgta tctgctagac tctacataga aactgaacat caagaacccc 800

 accaaaatat tacttttaaa aacaatgaca aaccacacaa ttgttgttga 850

 gtaaaccacg cacaatggca tgtctttctt tttctgccag aaaatctatt 900

 ttaagaaacc agaatagtca acagtgttca aaagaattga ctagttatcc 950

 ctgaggccct ttcaaacatg atcaaagatt tcccaatgtg atctcatcat 1000

 catggatact caatttgttt tttcttatag agaaaatgag tatataagac 1050

 aatatacaag aagaaatatc agtgagtttt aaatcagaac aagttacctg 1100

 tcacattgaa gaaaagggta ggcactaaag ggagaacaca gaaagaagaa 1150

 tttctaaaat attggattta cttcttatat tgagtcagat gcatactttt 1200

 agatttgcat tggggaaaat gtactagcta aaaatggata cacaatgaag 1250

 aattctattt ggctaattaa gaatgatata ctatgtacac ccaataagct 1300

 gtactagaat gaataaatta ctgataaggt tccaaaaaaa aaaaaaaaaa 1350

 aaaaaaaaaa aaaaa 1365

<210> 1576
<211> 218
<212> PRT
<213> Homo sapien

<400> 1576
 Met Thr Asp Gly Asp Tyr Asp Tyr Leu Ile Lys Leu Leu Ala Leu
   1               5                  10                  15

 Gly Asp Ser Gly Val Gly Lys Thr Thr Phe Leu Tyr Arg Tyr Thr
                  20                  25                  30

 Asp Asn Lys Phe Asn Pro Lys Phe Ile Thr Thr Val Gly Ile Asp
                  35                  40                  45

 Phe Arg Glu Lys Arg Val Val Tyr Asn Ala Gln Gly Pro Asn Gly
                  50                  55                  60

 Ser Ser Gly Lys Ala Phe Lys Val His Leu Gln Leu Trp Asp Thr
                  65                  70                  75

 Ala Gly Gln Glu Arg Phe Arg Ser Leu Thr Thr Ala Phe Phe Arg
                  80                  85                  90

 Asp Ala Met Gly Phe Leu Leu Met Phe Asp Leu Thr Ser Gln Gln
                  95                 100                 105

 Ser Phe Leu Asn Val Arg Asn Trp Met Ser Gln Leu Gln Ala Asn
                 110                 115                 120

 Ala Tyr Cys Glu Asn Pro Asp Ile Val Leu Ile Gly Asn Lys Ala
                 125                 130                 135

 Asp Leu Pro Asp Gln Arg Glu Val Asn Glu Arg Gln Ala Arg Glu
                 140                 145                 150

 Leu Ala Asp Lys Tyr Gly Ile Pro Tyr Phe Glu Thr Ser Ala Ala
                 155                 160                 165

 Thr Gly Gln Asn Val Glu Lys Ala Val Glu Thr Leu Leu Asp Leu
                 170                 175                 180

 Ile Met Lys Arg Met Glu Gln Cys Val Glu Lys Thr Gln Ile Pro
                 185                 190                 195

 Asp Thr Val Asn Gly Gly Asn Ser Gly Asn Leu Asp Gly Glu Lys
                 200                 205                 210

 Pro Pro Glu Lys Lys Cys Ile Cys
                 215

<210> 1577
<211> 3133
<212> DNA
<213> Homo sapien

<400> 1577
 ccgctgaggc cgcggcgccc gccagcctgt cccgcgccat ggccccgcgc 50

 gcccggcggc gccgcccgct gttcgcgctg ctgctgctct gcgcgctgct 100

 cgcccggctg caggtggctt tgcagatcgc tcctccatgt accagtgaga 150

 agcattatga gcatctggga cggtgctgta acaaatgtga accaggaaag 200

 tacatgtctt ctaaatgcac tactacctct gacagtgtat gtctgccctg 250

 tggcccggat gaatacttgg atagctggaa tgaagaagat aaatgcttgc 300

 tgcataaagt ttgtgataca ggcaaggccc tggtggccgt ggtcgccggc 350

 aacagcacga ccccccggcg ctgcgcgtgc acggctgggt accactggag 400

 ccaggactgc gagtgctgcc gccgcaacac cgagtgcgcg ccgggcctgg 450

 gcgcccagca cccgttgcag ctcaacaagg acacagtgtg caaaccttgc 500

 cttgcaggct acttctctga tgccttttcc tccacggaca aatgcagacc 550

 ctggaccaac tgtaccttcc ttggaaagag agtagaacat catgggacag 600

 agaaatccga tgcggtttgc agttcttctc tgccagctag aaaaccacca 650

 aatgaacccc atgtttactt gcccggttta ataattctgc ttctcttcgc 700

 gtctgtggcc ctggtggctg ccatcatctt tggcgtttgc tataggaaaa 750

 aagggaaagc actcacagct aatttgtggc actggatcaa tgaggcttgt 800

 ggccgcctaa gtggagataa ggagtcctca ggtgacagtt gtgtcagtac 850

 acacacggca aactttggtc agcagggagc atgtgaaggt gtcttactgc 900

 tgactctgga ggagaagaca tttccagaag atatgtgcta cccagatcaa 950

 ggtggtgtct gtcagggcac atgtgtagga ggtggtccct acgcacaagg 1000

 cgaagatgcc aggatgctct cattggtcag caagaccgag atagaggaag 1050

 acagcttcag acagatgccc acagaagatg aatacatgga caggccctcc 1100

 cagcccacag accagttact gttcctcact gagcctggaa gcaaatccac 1150

 acctcctttc tctgaacccc tggaggtggg ggagaatgac agtttaagcc 1200

 agtgcttcac ggggacacag agcacagtgg gttcagaaag ctgcaactgc 1250

 actgagcccc tgtgcaggac tgattggact cccatgtcct ctgaaaacta 1300

 cttgcaaaaa gaggtggaca gtggccattg cccgcactgg gcagccagcc 1350

 ccagccccaa ctgggcagat gtctgcacag gctgccggaa ccctcctggg 1400

 gaggactgtg aacccctcgt gggttcccca aaacgtggac ccttgcccca 1450

 gtgcgcctat ggcatgggcc ttccccctga agaagaagcc agcaggacgg 1500

 aggccagaga ccagcccgag gatggggctg atgggaggct cccaagctca 1550

 gcgagggcag gtgccgggtc tggaagctcc cctggtggcc agtcccctgc 1600

 atctggaaat gtgactggaa acagtaactc cacgttcatc tccagcgggc 1650

 aggtgatgaa cttcaagggc gacatcatcg tggtctacgt cagccagacc 1700

 tcgcaggagg gcgcggcggc ggctgcggag cccatgggcc gcccggtgca 1750

 ggaggagacc ctggcgcgcc gagactcctt cgcggggaac ggcccgcgct 1800

 tcccggaccc gtgcggcggc cccgaggggc tgcgggagcc ggagaaggcc 1850

 tcgaggccgg tgcaggagca aggcggggcc aaggcttgag cgccccccat 1900

 ggctgggagc ccgaagctcg gagccagggc tcgcgagggc agcaccgcag 1950

 cctctgcccc agccccggcc acccagggat cgatcggtac agtcgaggaa 2000

 gaccacccgg cattctctgc ccactttgcc ttccaggaaa tgggcttttc 2050

 aggaagtgaa ttgatgagga ctgtccccat gcccacggat gctcagcagc 2100

 ccgccgcact ggggcagatg tctcccctgc cactcctcaa actcgcagca 2150

 gtaatttgtg gcactatgac agctattttt atgactatcc tgttctgtgg 2200

 gggggggggt ctgttttccc cccatatttg tattcctttt cataactttt 2250

 cttgatatct ttcctccctc ttttttaatg taaaggtttt ctcaaaaatt 2300

 ctcctaaagg tgagggtctc tttcttttct cttttccttt tttttttctt 2350

 tttttggcaa cctggctctg gcccaggcta gagtgcagtg gtgcgattat 2400

 agcccggtgc agcctctaac tcctgggctc aagcaatcca agtgatcctc 2450

 ccacctcaac cttcggagta gctgggatca cagctgcagg ccacgcccag 2500

 cttcctcccc ccgactcccc ccccagagac acggtcccac catgttaccc 2550

 agcctggtct caaactcccc agctaaagca gtcctccagc ctcggcctcc 2600

 caaagtactg ggattacagg cgtgagcccc cacgctggcc tgctttacgt 2650

 attttctttt gtgcccctgc tcacagtgtt ttagagatgg ctttcccagt 2700

 gtgtgttcat tgtaaacact tttgggaaag ggctaaacat gtgaggcctg 2750

 gagatagttg ctaagttgct aggaacatgt ggtgggactt tcatattctg 2800

 aaaaatgttc tatattctca tttttctaaa agaaagaaaa aaggaaaccc 2850

 gatttatttc tcctgaatct ttttaagttt gtgtcgttcc ttaagcagaa 2900

 ctaagctcag tatgtgacct tacccgctag gtggttaatt tatccatgct 2950

 ggcagaggca ctcaggtact tggtaagcaa atttctaaaa ctccaagttg 3000

 ctgcagcttg gcattcttct tattctagag gtctctctgg aaaagatgga 3050

 gaaaatgaac aggacatggg gctcctggaa agaaagggcc cgggaagttc 3100

 aaggaagaat aaagttgaaa ttttaaaaaa aaa 3133

<210> 1578
<211> 616
<212> PRT
<213> Homo sapien

<400> 1578
 Met Ala Pro Arg Ala Arg Arg Arg Arg Pro Leu Phe Ala Leu Leu
   1               5                  10                  15

 Leu Leu Cys Ala Leu Leu Ala Arg Leu Gln Val Ala Leu Gln Ile
                  20                  25                  30

 Ala Pro Pro Cys Thr Ser Glu Lys His Tyr Glu His Leu Gly Arg
                  35                  40                  45

 Cys Cys Asn Lys Cys Glu Pro Gly Lys Tyr Met Ser Ser Lys Cys
                  50                  55                  60

 Thr Thr Thr Ser Asp Ser Val Cys Leu Pro Cys Gly Pro Asp Glu
                  65                  70                  75

 Tyr Leu Asp Ser Trp Asn Glu Glu Asp Lys Cys Leu Leu His Lys
                  80                  85                  90

 Val Cys Asp Thr Gly Lys Ala Leu Val Ala Val Val Ala Gly Asn
                  95                 100                 105

 Ser Thr Thr Pro Arg Arg Cys Ala Cys Thr Ala Gly Tyr His Trp
                 110                 115                 120

 Ser Gln Asp Cys Glu Cys Cys Arg Arg Asn Thr Glu Cys Ala Pro
                 125                 130                 135

 Gly Leu Gly Ala Gln His Pro Leu Gln Leu Asn Lys Asp Thr Val
                 140                 145                 150

 Cys Lys Pro Cys Leu Ala Gly Tyr Phe Ser Asp Ala Phe Ser Ser
                 155                 160                 165

 Thr Asp Lys Cys Arg Pro Trp Thr Asn Cys Thr Phe Leu Gly Lys
                 170                 175                 180

 Arg Val Glu His His Gly Thr Glu Lys Ser Asp Ala Val Cys Ser
                 185                 190                 195

 Ser Ser Leu Pro Ala Arg Lys Pro Pro Asn Glu Pro His Val Tyr
                 200                 205                 210

 Leu Pro Gly Leu Ile Ile Leu Leu Leu Phe Ala Ser Val Ala Leu
                 215                 220                 225

 Val Ala Ala Ile Ile Phe Gly Val Cys Tyr Arg Lys Lys Gly Lys
                 230                 235                 240

 Ala Leu Thr Ala Asn Leu Trp His Trp Ile Asn Glu Ala Cys Gly
                 245                 250                 255

 Arg Leu Ser Gly Asp Lys Glu Ser Ser Gly Asp Ser Cys Val Ser
                 260                 265                 270

 Thr His Thr Ala Asn Phe Gly Gln Gln Gly Ala Cys Glu Gly Val
                 275                 280                 285

 Leu Leu Leu Thr Leu Glu Glu Lys Thr Phe Pro Glu Asp Met Cys
                 290                 295                 300

 Tyr Pro Asp Gln Gly Gly Val Cys Gln Gly Thr Cys Val Gly Gly
                 305                 310                 315

 Gly Pro Tyr Ala Gln Gly Glu Asp Ala Arg Met Leu Ser Leu Val
                 320                 325                 330

 Ser Lys Thr Glu Ile Glu Glu Asp Ser Phe Arg Gln Met Pro Thr
                 335                 340                 345

 Glu Asp Glu Tyr Met Asp Arg Pro Ser Gln Pro Thr Asp Gln Leu
                 350                 355                 360

 Leu Phe Leu Thr Glu Pro Gly Ser Lys Ser Thr Pro Pro Phe Ser
                 365                 370                 375

 Glu Pro Leu Glu Val Gly Glu Asn Asp Ser Leu Ser Gln Cys Phe
                 380                 385                 390

 Thr Gly Thr Gln Ser Thr Val Gly Ser Glu Ser Cys Asn Cys Thr
                 395                 400                 405

 Glu Pro Leu Cys Arg Thr Asp Trp Thr Pro Met Ser Ser Glu Asn
                 410                 415                 420

 Tyr Leu Gln Lys Glu Val Asp Ser Gly His Cys Pro His Trp Ala
                 425                 430                 435

 Ala Ser Pro Ser Pro Asn Trp Ala Asp Val Cys Thr Gly Cys Arg
                 440                 445                 450

 Asn Pro Pro Gly Glu Asp Cys Glu Pro Leu Val Gly Ser Pro Lys
                 455                 460                 465

 Arg Gly Pro Leu Pro Gln Cys Ala Tyr Gly Met Gly Leu Pro Pro
                 470                 475                 480

 Glu Glu Glu Ala Ser Arg Thr Glu Ala Arg Asp Gln Pro Glu Asp
                 485                 490                 495

 Gly Ala Asp Gly Arg Leu Pro Ser Ser Ala Arg Ala Gly Ala Gly
                 500                 505                 510

 Ser Gly Ser Ser Pro Gly Gly Gln Ser Pro Ala Ser Gly Asn Val
                 515                 520                 525

 Thr Gly Asn Ser Asn Ser Thr Phe Ile Ser Ser Gly Gln Val Met
                 530                 535                 540

 Asn Phe Lys Gly Asp Ile Ile Val Val Tyr Val Ser Gln Thr Ser
                 545                 550                 555

 Gln Glu Gly Ala Ala Ala Ala Ala Glu Pro Met Gly Arg Pro Val
                 560                 565                 570

 Gln Glu Glu Thr Leu Ala Arg Arg Asp Ser Phe Ala Gly Asn Gly
                 575                 580                 585

 Pro Arg Phe Pro Asp Pro Cys Gly Gly Pro Glu Gly Leu Arg Glu
                 590                 595                 600

 Pro Glu Lys Ala Ser Arg Pro Val Gln Glu Gln Gly Gly Ala Lys
                 605                 610                 615

 Ala


<210> 1579
<211> 2668
<212> DNA
<213> Homo sapien

<400> 1579
 ctctctggat aggaagaaat atagtagaac cctttgaaaa tggatatttt 50

 cacatatttt cgttcagata caaaagctgg cagttactga aataaggact 100

 tgaagttcct tcctcttttt tttatgtctt aagagcagga aataaagaga 150

 cagctgaagg tgtagccttg accaactgaa agggaaatct tcatcctctg 200

 aaaaaacata tgtgattctc aaaaaacgca tctggaaaat tgataaagaa 250

 gcgattctgt agattctccc agcgctgttg ggctctcaat tccttctgtg 300

 aaggacaaca tatggtgatg gggaaatcag aagctttgag accctctaca 350

 cctggatatg aatccccctt ctaatactta ccagaaatga aggggatact 400

 cagggcagag ttctgaatct caaaacactc tactctggca aaggaatgaa 450

 gttattggag tgatgacagg aacacgggag aacaatgctc tgtttgggct 500

 ggatatttct ttggcttgtt gcaggagagc gaattaaagg atttaatatt 550

 tcaggttgtt ccacaaaaaa actcctttgg acatattcta caaggagtga 600

 agaggaattt gtcttatttt gtgatttacc agagccacag aaatcacatt 650

 tctgccacag aaatcgactc tcaccaaaac aagtccctga gcacctgccc 700

 ttcatgggta gtaacgacct atctgatgtc caatggtacc aacaaccttc 750

 gaatggagat ccattagagg acattaggaa aagctatcct cacatcattc 800

 aggacaaatg tacccttcac tttttgaccc caggggtgaa taattctggg 850

 tcatatattt gtagacccaa gatgattaag agcccctatg atgtagcctg 900

 ttgtgtcaag atgattttag aagttaagcc ccagacaaat gcatcctgtg 950

 agtattccgc atcacataag caagacctac ttcttgggag cactggctct 1000

 atttcttgcc ccagtctcag ctgccaaagt gatgcacaaa gtccagcggt 1050

 aacctggtac aagaatggaa aactcctctc tgtggaaagg agcaaccgaa 1100

 tcgtagtgga tgaagtttat gactatcacc agggcacata tgtatgtgat 1150

 tacactcagt cggatactgt gagttcgtgg acagtcagag ctgttgttca 1200

 agtgagaacc attgtgggag acactaaact caaaccagat attctggatc 1250

 ctgtcgagga cacactggaa gtagaacttg gaaagccttt aactattagc 1300

 tgcaaagcac gatttggctt tgaaagggtc tttaaccctg tcataaaatg 1350

 gtacatcaaa gattctgacc tagagtggga agtctcagta cctgaggcga 1400

 aaagtattaa atccacttta aaggatgaaa tcattgagcg taatatcatc 1450

 ttggaaaaag tcactcagcg tgatcttcgc aggaagtttg tttgctttgt 1500

 ccagaactcc attggaaaca caacccagtc cgtccaactg aaagaaaaga 1550

 gaggagtggt gctcctgtac atcctgcttg gcaccatcgg gaccctggtg 1600

 gccgtgctgg cggcgagtgc cctcctctac aggcactgga ttgaaatagt 1650

 gctgctgtac cggacctacc agagcaagga tcagacgctt ggggataaaa 1700

 aggattttga tgctttcgta tcctatgcaa aatggagctc ttttccaagt 1750

 gaggccactt catctctgag tgaagaacac ttggccctga gcctatttcc 1800

 tgatgtttta gaaaacaaat atggatatag cctgtgtttg cttgaaagag 1850

 atgtggctcc aggaggagtg tatgcagaag acattgtgag cattattaag 1900

 agaagcagaa gaggaatatt tatcttgagc cccaactatg tcaatggacc 1950

 cagtatcttt gaactacaag cagcagtgaa tcttgccttg gatgatcaaa 2000

 cactgaaact cattttaatt aagttctgtt acttccaaga gccagagtct 2050

 ctacctcatc tcgtgaaaaa agctctcagg gttttgccca cagttacttg 2100

 gagaggctta aaatcagttc ctcccaattc taggttctgg gccaaaatgc 2150

 gctaccacat gcctgtgaaa aactctcagg gattcacgtg gaaccagctc 2200

 agaattacct ctaggatttt tcagtggaaa ggactcagta gaacagaaac 2250

 cactgggagg agctcccagc ctaaggaatg gtgaaatgag ccctggagcc 2300

 ccctccagtc cagtccctgg gatagagatg ttgctggaca gaactcacag 2350

 ctctgtgtgt gtgtgttcag gctgatagga aattcaaaga gtctcctgcc 2400

 agcaccaagc aagcttgatg gacaatggag tgggattgag actgtggttt 2450

 agagcctttg atttcctgga ctggactgac ggcgagtgaa ttctctagac 2500

 cttgggtact ttcagtacac aacaccccta agatttccca gtggtccgag 2550

 cagaatcaga aaatacagct acttctgcct tatggctagg gaactgtcat 2600

 gtctaccatg tattgtacat atgactttat gtatacttgc aatcaaataa 2650

 atattatttt attagaaa 2668

<210> 1580
<211> 599
<212> PRT
<213> Homo sapien

<400> 1580
 Met Leu Cys Leu Gly Trp Ile Phe Leu Trp Leu Val Ala Gly Glu
   1               5                  10                  15

 Arg Ile Lys Gly Phe Asn Ile Ser Gly Cys Ser Thr Lys Lys Leu
                  20                  25                  30

 Leu Trp Thr Tyr Ser Thr Arg Ser Glu Glu Glu Phe Val Leu Phe
                  35                  40                  45

 Cys Asp Leu Pro Glu Pro Gln Lys Ser His Phe Cys His Arg Asn
                  50                  55                  60

 Arg Leu Ser Pro Lys Gln Val Pro Glu His Leu Pro Phe Met Gly
                  65                  70                  75

 Ser Asn Asp Leu Ser Asp Val Gln Trp Tyr Gln Gln Pro Ser Asn
                  80                  85                  90

 Gly Asp Pro Leu Glu Asp Ile Arg Lys Ser Tyr Pro His Ile Ile
                  95                 100                 105

 Gln Asp Lys Cys Thr Leu His Phe Leu Thr Pro Gly Val Asn Asn
                 110                 115                 120

 Ser Gly Ser Tyr Ile Cys Arg Pro Lys Met Ile Lys Ser Pro Tyr
                 125                 130                 135

 Asp Val Ala Cys Cys Val Lys Met Ile Leu Glu Val Lys Pro Gln
                 140                 145                 150

 Thr Asn Ala Ser Cys Glu Tyr Ser Ala Ser His Lys Gln Asp Leu
                 155                 160                 165

 Leu Leu Gly Ser Thr Gly Ser Ile Ser Cys Pro Ser Leu Ser Cys
                 170                 175                 180

 Gln Ser Asp Ala Gln Ser Pro Ala Val Thr Trp Tyr Lys Asn Gly
                 185                 190                 195

 Lys Leu Leu Ser Val Glu Arg Ser Asn Arg Ile Val Val Asp Glu
                 200                 205                 210

 Val Tyr Asp Tyr His Gln Gly Thr Tyr Val Cys Asp Tyr Thr Gln
                 215                 220                 225

 Ser Asp Thr Val Ser Ser Trp Thr Val Arg Ala Val Val Gln Val
                 230                 235                 240

 Arg Thr Ile Val Gly Asp Thr Lys Leu Lys Pro Asp Ile Leu Asp
                 245                 250                 255

 Pro Val Glu Asp Thr Leu Glu Val Glu Leu Gly Lys Pro Leu Thr
                 260                 265                 270

 Ile Ser Cys Lys Ala Arg Phe Gly Phe Glu Arg Val Phe Asn Pro
                 275                 280                 285

 Val Ile Lys Trp Tyr Ile Lys Asp Ser Asp Leu Glu Trp Glu Val
                 290                 295                 300

 Ser Val Pro Glu Ala Lys Ser Ile Lys Ser Thr Leu Lys Asp Glu
                 305                 310                 315

 Ile Ile Glu Arg Asn Ile Ile Leu Glu Lys Val Thr Gln Arg Asp
                 320                 325                 330

 Leu Arg Arg Lys Phe Val Cys Phe Val Gln Asn Ser Ile Gly Asn
                 335                 340                 345

 Thr Thr Gln Ser Val Gln Leu Lys Glu Lys Arg Gly Val Val Leu
                 350                 355                 360

 Leu Tyr Ile Leu Leu Gly Thr Ile Gly Thr Leu Val Ala Val Leu
                 365                 370                 375

 Ala Ala Ser Ala Leu Leu Tyr Arg His Trp Ile Glu Ile Val Leu
                 380                 385                 390

 Leu Tyr Arg Thr Tyr Gln Ser Lys Asp Gln Thr Leu Gly Asp Lys
                 395                 400                 405

 Lys Asp Phe Asp Ala Phe Val Ser Tyr Ala Lys Trp Ser Ser Phe
                 410                 415                 420

 Pro Ser Glu Ala Thr Ser Ser Leu Ser Glu Glu His Leu Ala Leu
                 425                 430                 435

 Ser Leu Phe Pro Asp Val Leu Glu Asn Lys Tyr Gly Tyr Ser Leu
                 440                 445                 450

 Cys Leu Leu Glu Arg Asp Val Ala Pro Gly Gly Val Tyr Ala Glu
                 455                 460                 465

 Asp Ile Val Ser Ile Ile Lys Arg Ser Arg Arg Gly Ile Phe Ile
                 470                 475                 480

 Leu Ser Pro Asn Tyr Val Asn Gly Pro Ser Ile Phe Glu Leu Gln
                 485                 490                 495

 Ala Ala Val Asn Leu Ala Leu Asp Asp Gln Thr Leu Lys Leu Ile
                 500                 505                 510

 Leu Ile Lys Phe Cys Tyr Phe Gln Glu Pro Glu Ser Leu Pro His
                 515                 520                 525

 Leu Val Lys Lys Ala Leu Arg Val Leu Pro Thr Val Thr Trp Arg
                 530                 535                 540

 Gly Leu Lys Ser Val Pro Pro Asn Ser Arg Phe Trp Ala Lys Met
                 545                 550                 555

 Arg Tyr His Met Pro Val Lys Asn Ser Gln Gly Phe Thr Trp Asn
                 560                 565                 570

 Gln Leu Arg Ile Thr Ser Arg Ile Phe Gln Trp Lys Gly Leu Ser
                 575                 580                 585

 Arg Thr Glu Thr Thr Gly Arg Ser Ser Gln Pro Lys Glu Trp
                 590                 595

<210> 1581
<211> 942
<212> DNA
<213> Homo sapien

<400> 1581
 actcagggca gagcctggct gctgggcaga agggcacttg ggcgggctgc 50

 ttcagagagg gccattcggt gtcctggccc acagagagag taaacagtga 100

 gagaccaaga gagcaaacca gagagatagg gagggggaat gcaaggggtc 150

 cctgggggac tcaggggtcc cagtggagaa tgagaggcag gccccccgtg 200

 gtgggccggg gacctggctg ccagaggacc gggctggtga ggaggcgagg 250

 atgtggactt tcgtcaccca gctgttggtc acgctggtgc tgctgagctt 300

 cttcctggtc agctgtcaga acgtgatgca cattgtcagg gggtccctgt 350

 gctttgtgct aaagcacatc caccaggtgg agctgagagg gagtggccta 400

 cagccggacc tgatagaggg caggaagggg gcgcagatag tgaagcgggc 450

 cagcctgaaa agggggaaac agtgaccccg agccgctctc cttggagtag 500

 cctctcggga ggatcacacc tcgacaccca acccctgaac cccacacact 550

 ctctgccatg cacacaggag gagagctgga cctgagggcc accgcagcgg 600

 tgcacacatt cctctgggct gacggcatga cctctgtaag ggactcctgc 650

 tagtcccctc ttggcatgaa tgactgactg tagacgcatg acctccaggc 700

 ttcaatcctg cctcttgcaa tgacagctga tctgtcggaa ccaggacaca 750

 aaagcagcaa gaagcgggga gagagaggga tagaaaacaa gcgcaggaga 800

 gcctgcgaac gcaaaagtga atgagggctt tttgtggctg gggatgggtt 850

 ttggttttgg ggtttttttt ttaaattgtt ttgacttcgt acagggtact 900

 ttttcccaac ctcatctgtc agaaatccat gtgggcttcc tg 942

<210> 1582
<211> 74
<212> PRT
<213> Homo sapien

<400> 1582
 Met Trp Thr Phe Val Thr Gln Leu Leu Val Thr Leu Val Leu Leu
   1               5                  10                  15

 Ser Phe Phe Leu Val Ser Cys Gln Asn Val Met His Ile Val Arg
                  20                  25                  30

 Gly Ser Leu Cys Phe Val Leu Lys His Ile His Gln Val Glu Leu
                  35                  40                  45

 Arg Gly Ser Gly Leu Gln Pro Asp Leu Ile Glu Gly Arg Lys Gly
                  50                  55                  60

 Ala Gln Ile Val Lys Arg Ala Ser Leu Lys Arg Gly Lys Gln
                  65                  70

<210> 1583
<211> 1669
<212> DNA
<213> Homo sapien

<400> 1583
 ctccctcagc aaggacagca gaggaccagc taagagggag agaagcaact 50

 acagaccccc cctgaaaaca accctcagac gccacatccc ctgacaagct 100

 gccaggcagg ttctcttcct ctcacatact gacccacggc tccaccctct 150

 ctcccctgga aaggacacca tgagcactga aagcatgatc cgggacgtgg 200

 agctggccga ggaggcgctc cccaagaaga caggggggcc ccagggctcc 250

 aggcggtgct tgttcctcag cctcttctcc ttcctgatcg tggcaggcgc 300

 caccacgctc ttctgcctgc tgcactttgg agtgatcggc ccccagaggg 350

 aagagttccc cagggacctc tctctaatca gccctctggc ccaggcagtc 400

 agatcatctt ctcgaacccc gagtgacaag cctgtagccc atgttgtagc 450

 aaaccctcaa gctgaggggc agctccagtg gctgaaccgc cgggccaatg 500

 ccctcctggc caatggcgtg gagctgagag ataaccagct ggtggtgcca 550

 tcagagggcc tgtacctcat ctactcccag gtcctcttca agggccaagg 600

 ctgcccctcc acccatgtgc tcctcaccca caccatcagc cgcatcgccg 650

 tctcctacca gaccaaggtc aacctcctct ctgccatcaa gagcccctgc 700

 cagagggaga ccccagaggg ggctgaggcc aagccctggt atgagcccat 750

 ctatctggga ggggtcttcc agctggagaa gggtgaccga ctcagcgctg 800

 agatcaatcg gcccgactat ctcgactttg ccgagtctgg gcaggtctac 850

 tttgggatca ttgccctgtg aggaggacga acatccaacc ttcccaaacg 900

 cctcccctgc cccaatccct ttattacccc ctccttcaga caccctcaac 950

 ctcttctggc tcaaaaagag aattgggggc ttagggtcgg aacccaagct 1000

 tagaacttta agcaacaaga ccaccacttc gaaacctggg attcaggaat 1050

 gtgtggcctg cacagtgaag tgctggcaac cactaagaat tcaaactggg 1100

 gcctccagaa ctcactgggg cctacagctt tgatccctga catctggaat 1150

 ctggagacca gggagccttt ggttctggcc agaatgctgc aggacttgag 1200

 aagacctcac ctagaaattg acacaagtgg accttaggcc ttcctctctc 1250

 cagatgtttc cagacttcct tgagacacgg agcccagccc tccccatgga 1300

 gccagctccc tctatttatg tttgcacttg tgattattta ttatttattt 1350

 attatttatt tatttacaga tgaatgtatt tatttgggag accggggtat 1400

 cctgggggac ccaatgtagg agctgccttg gctcagacat gttttccgtg 1450

 aaaacggagc tgaacaatag gctgttccca tgtagccccc tggcctctgt 1500

 gccttctttt gattatgttt tttaaaatat ttatctgatt aagttgtcta 1550

 aacaatgctg atttggtgac caactgtcac tcattgctga gcctctgctc 1600

 cccaggggag ttgtgtctgt aatcgcccta ctattcagtg gcgagaaata 1650

 aagtttgctt agaaaagaa 1669

<210> 1584
<211> 233
<212> PRT
<213> Homo sapien

<400> 1584
 Met Ser Thr Glu Ser Met Ile Arg Asp Val Glu Leu Ala Glu Glu
   1               5                  10                  15

 Ala Leu Pro Lys Lys Thr Gly Gly Pro Gln Gly Ser Arg Arg Cys
                  20                  25                  30

 Leu Phe Leu Ser Leu Phe Ser Phe Leu Ile Val Ala Gly Ala Thr
                  35                  40                  45

 Thr Leu Phe Cys Leu Leu His Phe Gly Val Ile Gly Pro Gln Arg
                  50                  55                  60

 Glu Glu Phe Pro Arg Asp Leu Ser Leu Ile Ser Pro Leu Ala Gln
                  65                  70                  75

 Ala Val Arg Ser Ser Ser Arg Thr Pro Ser Asp Lys Pro Val Ala
                  80                  85                  90

 His Val Val Ala Asn Pro Gln Ala Glu Gly Gln Leu Gln Trp Leu
                  95                 100                 105

 Asn Arg Arg Ala Asn Ala Leu Leu Ala Asn Gly Val Glu Leu Arg
                 110                 115                 120

 Asp Asn Gln Leu Val Val Pro Ser Glu Gly Leu Tyr Leu Ile Tyr
                 125                 130                 135

 Ser Gln Val Leu Phe Lys Gly Gln Gly Cys Pro Ser Thr His Val
                 140                 145                 150

 Leu Leu Thr His Thr Ile Ser Arg Ile Ala Val Ser Tyr Gln Thr
                 155                 160                 165

 Lys Val Asn Leu Leu Ser Ala Ile Lys Ser Pro Cys Gln Arg Glu
                 170                 175                 180

 Thr Pro Glu Gly Ala Glu Ala Lys Pro Trp Tyr Glu Pro Ile Tyr
                 185                 190                 195

 Leu Gly Gly Val Phe Gln Leu Glu Lys Gly Asp Arg Leu Ser Ala
                 200                 205                 210

 Glu Ile Asn Arg Pro Asp Tyr Leu Asp Phe Ala Glu Ser Gly Gln
                 215                 220                 225

 Val Tyr Phe Gly Ile Ile Ala Leu
                 230

<210> 1585
<211> 2564
<212> DNA
<213> Homo sapien

<400> 1585
 aatagcaata gctttatagc agctccggtt acctgtttta aacatggaag 50

 gagagtcgct cccagatagc cctcacgagt ggccctggag cagggagtgg 100

 tggagcagat cttccttgtt tgggaggagc ctgaggtgga cctcgcgtcc 150

 tgagtctgga aggcacctat ggggacctgc tggggtgata tctcagaaaa 200

 tgtgagagta gaagttccca atacagactg cagcctacct accaaagtct 250

 tctggattgc tggaattgta aaattagcag gttacaatgc ccttttaaga 300

 tatgaaggat ttgaaaatga ctctggtctg gacttctggt gcaatatatg 350

 tggttctgat atccatccag ttggttggtg tgcagccagc ggaaaacctc 400

 ttgttcctcc tagaactatt cagcataaat atacaaactg gaaagctttt 450

 ctagtgaaac gacttactgg tgccaaaaca ctgcctcctg atttctccca 500

 aaaggtttca gagagtatgc agtatccttt caaaccttgc atgagagtag 550

 aagtggttga caagaggcat ttgtgtcgaa cacgagtagc agtggtggaa 600

 agtgtaattg gaggaagatt aagactagtg tatgaagaaa gcgaagatag 650

 aacagatgac ttctggtgcc atatgcacag cccattaata catcatattg 700

 gttggtctcg aagcataggt catcgattca aaagatctga tattacaaag 750

 aaacaggatg gacattttga tacaccacca catttatttg ctaaggtaaa 800

 agaagtagac cagagtgggg aatggttcaa ggaaggaatg aaattggaag 850

 ctatagaccc attaaatctt tctacaatat gtgtcgcaac cattagaaag 900

 gtgctagctg acggattcct gatgattggg atcgatggct cagaagcagc 950

 agacggatct gactggttct gttaccatgc aacctctcct tctattttcc 1000

 ctgtcggttt ctgtgaaatt aacatgattg aacttactcc acccagaggt 1050

 tacacaaaac ttccttttaa atggtttgac tacctcaggg aaactggctc 1100

 cattgcagca ccagtaaaac tatttaataa ggatgttcca aatcacggat 1150

 ttcgtgtagg aatgaaatta gaagcagtag atctcatgga gccacgttta 1200

 atatgtgtag ccacagtaac tcgaattatt catcgtctct tgaggataca 1250

 ttttgatgga tgggaagaag agtatgatca gtgggtagac tgtgagtcac 1300

 ctgacctcta tcctgtaggg tggtgtcagt taactggata tcaactacag 1350

 cctccagcat cacagtgtaa gttggtatac agaaaaggtg tccttttgta 1400

 aaaatcagca attctccaga ggactatctc acataagtca tcttatgagc 1450

 tcacaggaca agaatatacc tatgtctgat tggttgccag gtaagacatt 1500

 aagactcaac aacaatatca cagaatcaga ccatgtgtcc catggcaatg 1550

 tgaatccaat agtcaattac ataatgacta tagaaacaca acagtcacca 1600

 aattaaacta gacttactat tttagtgagt taaaaattac atactaaaag 1650

 tttattggta ggtaataaat gcttttgagt aaatagtgga aaatgtctca 1700

 tgttgaggct atggttttgt aggaacaagt acccttattt tcagagcatc 1750

 atgtacttaa gtataatggt cttggtaaag atagttcata taagttgtat 1800

 ctagacaact gtatcgtcta aattgtaaac aattatctag taccaatttt 1850

 ccctttttat ttttcagcat caagagaaaa ccaatcagct tcatcaaaac 1900

 agaagaaaaa ggctaagtcc cagcaataca aaggacataa gaaaagtggg 1950

 tcaccacgtg gtgttcacat acattttcta attgttaact aattggagtc 2000

 acagtattct tggacagaaa atgatatatc ttgtgagaac tgatgattgt 2050

 gcattatgta ttatgcttaa aggtgcagta tgccataaaa ggcaaaccct 2100

 tgcaataatg agaaacactg atattttact aacaggagaa atgattacca 2150

 cagtatttaa agtatacgtg gtaaagaata gagtctgtga atgattcttg 2200

 aaataatatg taaaacctac tgaaagttaa tcctttttaa aaactttatt 2250

 taaaaagaaa aattagcagc caggtgcagt ggctcacgcc tgtaatccca 2300

 gcactttagg aggccgaggc tggcagatca caaggtcagg agatcgagac 2350

 catcctggct aacacggtga aaccctgtct ccaccaaaaa tacaaaaaat 2400

 ctgccgggcg tggtggcaca cgcctgaagt cccagctact caggaggctg 2450

 aggcaagaga atcacttgaa cccaggaggc agaggttgca gtgggccaag 2500

 atcacgccac tacattccag ctgggcaaca cagcaagact ctgtctcaaa 2550

 aaaaaaaaaa aaaa 2564

<210> 1586
<211> 410
<212> PRT
<213> Homo sapien

<400> 1586
 Met Gly Thr Cys Trp Gly Asp Ile Ser Glu Asn Val Arg Val Glu
   1               5                  10                  15

 Val Pro Asn Thr Asp Cys Ser Leu Pro Thr Lys Val Phe Trp Ile
                  20                  25                  30

 Ala Gly Ile Val Lys Leu Ala Gly Tyr Asn Ala Leu Leu Arg Tyr
                  35                  40                  45

 Glu Gly Phe Glu Asn Asp Ser Gly Leu Asp Phe Trp Cys Asn Ile
                  50                  55                  60

 Cys Gly Ser Asp Ile His Pro Val Gly Trp Cys Ala Ala Ser Gly
                  65                  70                  75

 Lys Pro Leu Val Pro Pro Arg Thr Ile Gln His Lys Tyr Thr Asn
                  80                  85                  90

 Trp Lys Ala Phe Leu Val Lys Arg Leu Thr Gly Ala Lys Thr Leu
                  95                 100                 105

 Pro Pro Asp Phe Ser Gln Lys Val Ser Glu Ser Met Gln Tyr Pro
                 110                 115                 120

 Phe Lys Pro Cys Met Arg Val Glu Val Val Asp Lys Arg His Leu
                 125                 130                 135

 Cys Arg Thr Arg Val Ala Val Val Glu Ser Val Ile Gly Gly Arg
                 140                 145                 150

 Leu Arg Leu Val Tyr Glu Glu Ser Glu Asp Arg Thr Asp Asp Phe
                 155                 160                 165

 Trp Cys His Met His Ser Pro Leu Ile His His Ile Gly Trp Ser
                 170                 175                 180

 Arg Ser Ile Gly His Arg Phe Lys Arg Ser Asp Ile Thr Lys Lys
                 185                 190                 195

 Gln Asp Gly His Phe Asp Thr Pro Pro His Leu Phe Ala Lys Val
                 200                 205                 210

 Lys Glu Val Asp Gln Ser Gly Glu Trp Phe Lys Glu Gly Met Lys
                 215                 220                 225

 Leu Glu Ala Ile Asp Pro Leu Asn Leu Ser Thr Ile Cys Val Ala
                 230                 235                 240

 Thr Ile Arg Lys Val Leu Ala Asp Gly Phe Leu Met Ile Gly Ile
                 245                 250                 255

 Asp Gly Ser Glu Ala Ala Asp Gly Ser Asp Trp Phe Cys Tyr His
                 260                 265                 270

 Ala Thr Ser Pro Ser Ile Phe Pro Val Gly Phe Cys Glu Ile Asn
                 275                 280                 285

 Met Ile Glu Leu Thr Pro Pro Arg Gly Tyr Thr Lys Leu Pro Phe
                 290                 295                 300

 Lys Trp Phe Asp Tyr Leu Arg Glu Thr Gly Ser Ile Ala Ala Pro
                 305                 310                 315

 Val Lys Leu Phe Asn Lys Asp Val Pro Asn His Gly Phe Arg Val
                 320                 325                 330

 Gly Met Lys Leu Glu Ala Val Asp Leu Met Glu Pro Arg Leu Ile
                 335                 340                 345

 Cys Val Ala Thr Val Thr Arg Ile Ile His Arg Leu Leu Arg Ile
                 350                 355                 360

 His Phe Asp Gly Trp Glu Glu Glu Tyr Asp Gln Trp Val Asp Cys
                 365                 370                 375

 Glu Ser Pro Asp Leu Tyr Pro Val Gly Trp Cys Gln Leu Thr Gly
                 380                 385                 390

 Tyr Gln Leu Gln Pro Pro Ala Ser Gln Cys Lys Leu Val Tyr Arg
                 395                 400                 405

 Lys Gly Val Leu Leu
                 410

<210> 1587
<211> 4193
<212> DNA
<213> Homo sapien

<400> 1587
 catggcggcg actgcggcaa agcgagagcc tcggagacgc cgctgccgcc 50

 agcacagccg gagatctgag ccgacactgg gggcagtccg cgagccccgc 100

 actctctcga tgagtcggag aagtcccgtt gtatcagagt aagatggacg 150

 gtagctttga ttgtgattgt ggtgagctgg agccacctga tcactaacaa 200

 aagacatctt ctgttaacca acagccgcca ggcttcctgt tgaaataaat 250

 atatagcaac aaaggaaaaa aagaagcaaa acggaaatag tgcttaccag 300

 caccttagaa tgatgctgct caggaccagt ccaacactga atgtatctgc 350

 actgtgagga gaatgttcat agaagcctgt tgtgtgcata tttattcact 400

 ttttgttaaa tgttaaatcg tttagcacgg taatctgagt gcacagtatg 450

 tcatttcatt ccgtttgagt ttcttgtttt cgttaaatgt ctgcagagtt 500

 gctgcccctt tcttgaacta tgagtactgc aatcttttta attctcaata 550

 tgaatagagc tttttgagct ttaaatctaa ggggaactcg acaggcctgt 600

 ttggcatatg caatgaacat caagaaacca tcttgctgtg gaagcataat 650

 tatttttctt ctcccttttt gaaagatctt tccttttgat gccagttttc 700

 ttccttgttt acacaagttc aatttgaaag gaaaaggcaa tagtaagggt 750

 ttcaaaatgg cagagaaatt tgaaagtctc atgaacattc atggttttga 800

 tctgggttct aggtatatgg acttaaaacc attgggttgt ggaggcaatg 850

 gcttggtttt ttctgctgta gacaatgact gtgacaaaag agtagccatc 900

 aagaaaattg tccttactga tccccagagt gtcaaacatg ctctacgtga 950

 aatcaaaatt attagaagac ttgaccatga taacattgtg aaagtgtttg 1000

 agattcttgg tcccagtgga agccaattaa cagacgatgt gggctctctt 1050

 acggaactga acagtgttta cattgttcag gagtacatgg agacagactt 1100

 ggctaatgtg ctggagcagg gccctttact ggaagagcat gccaggcttt 1150

 tcatgtatca gctgctacgg gggctcaagt atattcactc tgcaaatgta 1200

 ctgcacagag atctcaaacc agctaatctt ttcattaata cggaagactt 1250

 ggtgctgaag ataggtgact ttggtcttgc acggatcatg gatcctcatt 1300

 attcccataa gggtcatctt tctgaaggat tggttactaa atggtacaga 1350

 tctccacgtc ttttactttc tcctaataat tatactaaag ccattgacat 1400

 gtgggctgca ggctgcatct ttgctgaaat gctgactggt aaaacccttt 1450

 ttgcaggtgc acatgaactt gaacagatgc agctgatttt agaatctatt 1500

 cctgttgtac atgaggaaga tcgtcaggag cttctcagcg taattccagt 1550

 ttacattaga aatgacatga ctgagccaca caaaccttta actcagctgc 1600

 ttccaggaat tagtcgagaa gcactggatt tcctggaaca aattttgaca 1650

 tttagcccca tggatcggtt aacagcagaa gaagcactct cccatcctta 1700

 catgagcata tattcttttc caatggatga gccaatttca agccatcctt 1750

 ttcatattga agatgaagtt gatgatattt tgcttatgga tgaaactcac 1800

 agtcacattt ataactggga aaggtatcat gattgtcagt tttcagagca 1850

 tgattggcct gtacataaca actttgatat tgatgaagtt cagcttgatc 1900

 caagagctct gtccgatgtc actgatgaag aagaagtaca agttgatccc 1950

 cgaaaatatt tggatggaga tcgggaaaag tatctggagg atcctgcttt 2000

 tgataccaat tactctactg agccttgttg gcaatactca gatcatcatg 2050

 aaaacaaata ttgtgatctg gagtgtagcc atacttgtaa ctacaaaacg 2100

 aggtcatcat catatttaga taacttagtt tggagagaga gtgaagttaa 2150

 ccattactat gaacccaagc ttattataga tctttccaat tggaaagaac 2200

 aaagcaaaga aaaatctgat aagaaaggca aatcaaaatg tgaaaggaat 2250

 ggattggtta aagcccagat agcgctagag gaagcatcac agcaactggc 2300

 tggaaaagaa agggaaaaga atcagggatt tgattttgat tcctttattg 2350

 caggaactat tcagcttagt tcccagcatg agcctactga tgttgttgat 2400

 aaattaaatg acttgaatag ctcagtgtcc caactagaat tgaaaagttt 2450

 gatatcaaag tcagtaagcc aagaaaaaca ggaaaaagga atggcaaatc 2500

 tggctcaatt agaagccttg taccagtctt cttgggacag ccagtttgtg 2550

 agtggtgggg aggactgttt tttcataaat cagttttgtg aggtaaggaa 2600

 ggatgaacaa gttgagaagg aaaacactta cactagttac ttggacaagt 2650

 tctttagcag gaaagaagat actgaaatgc tagaaactga gccagtagag 2700

 gatgggaagc ttggggagag aggacatgag gaaggatttc tgaacaacag 2750

 tggggagttc ctctttaaca agcagctcga gtccataggc atcccacagt 2800

 ttcacagtcc agttgggtca ccacttaagt caatacaggc cacattaaca 2850

 ccttctgcta tgaaatcttc ccctcaaatt cctcatcaaa catacagcag 2900

 cattctgaaa catctgaact aaaacactca gcagacattt atctttgtat 2950

 tcttcatgaa atgtgttttg tcttttttta ttactagtgt ttaagtcatt 3000

 ttttacttga atcagatggt gtcatttagt aaggatttta tgagttcttg 3050

 ttttttaaaa tccagacttt ctttttctac atgtgagata gttttcattt 3100

 taactggcat gtcatttgca cacaaaaata aagactagag caaaataatg 3150

 caacgcagga ggagaaaaga aatgcactaa gacaagaaca ttctctcata 3200

 gaacattgat ctgttttaca ggaaacaaac cttgccttga aatttacaca 3250

 gtgagactgt acataattgc atgaaaatag ctattttttt cctaagacat 3300

 ttttcattca tgaatatttt caagtttttc atactgtaca catttcttaa 3350

 aacacatgat accagcagca actgaaaatg aatgccgaat ttggtacaca 3400

 tgtgttatct acctcaaggt aacaagagta tgtggcaaaa catataccac 3450

 ccatagtgct tcacaaaatg cacttctatt tagccagcgt ttattgtagt 3500

 aaactattct taataaaact cactcactgt ttataaatgt tctggtatgc 3550

 attctttata gtgaagtgtt aatacatcac atcttattta ttttagcaaa 3600

 tcagtatatt ttctgtattt aattataaaa aattaactta gtttttaaaa 3650

 tttatttgca aatatacttt ttccatttgg cactatggtt tgttgcctac 3700

 ctagctgcat ctataatgtc agcttatcct aaggctgtcc acgtacttaa 3750

 tttacttaag tgttcatttt aagtaacgtg ctcactgtgt ataggaattt 3800

 gtattttgga ggtgcttgat ctatctacaa agaaaaatta attaggaatt 3850

 actttattat aaaatgctcc tagaagtctt aattgtgttt attttttaaa 3900

 aaaacaaatg ttagacttgt gtgcatggaa gtaattaagg tacatcatta 3950

 ttgtagtttg aaagttgtac atgataagac attttgtttt tactgtatgt 4000

 ttttactgaa tgatctattc cccatcccaa ggcaagcatg aataaaatta 4050

 ggttaaacgt agcatgtggc atcgcagtct cttagaattt gtttcatcta 4100

 ttttatttta ttgaatactg tctgtatctt tggttatcct gtttgaagaa 4150

 aaaggacaaa taaaacatgg ccagcaaata caaaaaaaaa aaa 4193

<210> 1588
<211> 721
<212> PRT
<213> Homo sapien

<400> 1588
 Met Ala Glu Lys Phe Glu Ser Leu Met Asn Ile His Gly Phe Asp
   1               5                  10                  15

 Leu Gly Ser Arg Tyr Met Asp Leu Lys Pro Leu Gly Cys Gly Gly
                  20                  25                  30

 Asn Gly Leu Val Phe Ser Ala Val Asp Asn Asp Cys Asp Lys Arg
                  35                  40                  45

 Val Ala Ile Lys Lys Ile Val Leu Thr Asp Pro Gln Ser Val Lys
                  50                  55                  60

 His Ala Leu Arg Glu Ile Lys Ile Ile Arg Arg Leu Asp His Asp
                  65                  70                  75

 Asn Ile Val Lys Val Phe Glu Ile Leu Gly Pro Ser Gly Ser Gln
                  80                  85                  90

 Leu Thr Asp Asp Val Gly Ser Leu Thr Glu Leu Asn Ser Val Tyr
                  95                 100                 105

 Ile Val Gln Glu Tyr Met Glu Thr Asp Leu Ala Asn Val Leu Glu
                 110                 115                 120

 Gln Gly Pro Leu Leu Glu Glu His Ala Arg Leu Phe Met Tyr Gln
                 125                 130                 135

 Leu Leu Arg Gly Leu Lys Tyr Ile His Ser Ala Asn Val Leu His
                 140                 145                 150

 Arg Asp Leu Lys Pro Ala Asn Leu Phe Ile Asn Thr Glu Asp Leu
                 155                 160                 165

 Val Leu Lys Ile Gly Asp Phe Gly Leu Ala Arg Ile Met Asp Pro
                 170                 175                 180

 His Tyr Ser His Lys Gly His Leu Ser Glu Gly Leu Val Thr Lys
                 185                 190                 195

 Trp Tyr Arg Ser Pro Arg Leu Leu Leu Ser Pro Asn Asn Tyr Thr
                 200                 205                 210

 Lys Ala Ile Asp Met Trp Ala Ala Gly Cys Ile Phe Ala Glu Met
                 215                 220                 225

 Leu Thr Gly Lys Thr Leu Phe Ala Gly Ala His Glu Leu Glu Gln
                 230                 235                 240

 Met Gln Leu Ile Leu Glu Ser Ile Pro Val Val His Glu Glu Asp
                 245                 250                 255

 Arg Gln Glu Leu Leu Ser Val Ile Pro Val Tyr Ile Arg Asn Asp
                 260                 265                 270

 Met Thr Glu Pro His Lys Pro Leu Thr Gln Leu Leu Pro Gly Ile
                 275                 280                 285

 Ser Arg Glu Ala Leu Asp Phe Leu Glu Gln Ile Leu Thr Phe Ser
                 290                 295                 300

 Pro Met Asp Arg Leu Thr Ala Glu Glu Ala Leu Ser His Pro Tyr
                 305                 310                 315

 Met Ser Ile Tyr Ser Phe Pro Met Asp Glu Pro Ile Ser Ser His
                 320                 325                 330

 Pro Phe His Ile Glu Asp Glu Val Asp Asp Ile Leu Leu Met Asp
                 335                 340                 345

 Glu Thr His Ser His Ile Tyr Asn Trp Glu Arg Tyr His Asp Cys
                 350                 355                 360

 Gln Phe Ser Glu His Asp Trp Pro Val His Asn Asn Phe Asp Ile
                 365                 370                 375

 Asp Glu Val Gln Leu Asp Pro Arg Ala Leu Ser Asp Val Thr Asp
                 380                 385                 390

 Glu Glu Glu Val Gln Val Asp Pro Arg Lys Tyr Leu Asp Gly Asp
                 395                 400                 405

 Arg Glu Lys Tyr Leu Glu Asp Pro Ala Phe Asp Thr Asn Tyr Ser
                 410                 415                 420

 Thr Glu Pro Cys Trp Gln Tyr Ser Asp His His Glu Asn Lys Tyr
                 425                 430                 435

 Cys Asp Leu Glu Cys Ser His Thr Cys Asn Tyr Lys Thr Arg Ser
                 440                 445                 450

 Ser Ser Tyr Leu Asp Asn Leu Val Trp Arg Glu Ser Glu Val Asn
                 455                 460                 465

 His Tyr Tyr Glu Pro Lys Leu Ile Ile Asp Leu Ser Asn Trp Lys
                 470                 475                 480

 Glu Gln Ser Lys Glu Lys Ser Asp Lys Lys Gly Lys Ser Lys Cys
                 485                 490                 495

 Glu Arg Asn Gly Leu Val Lys Ala Gln Ile Ala Leu Glu Glu Ala
                 500                 505                 510

 Ser Gln Gln Leu Ala Gly Lys Glu Arg Glu Lys Asn Gln Gly Phe
                 515                 520                 525

 Asp Phe Asp Ser Phe Ile Ala Gly Thr Ile Gln Leu Ser Ser Gln
                 530                 535                 540

 His Glu Pro Thr Asp Val Val Asp Lys Leu Asn Asp Leu Asn Ser
                 545                 550                 555

 Ser Val Ser Gln Leu Glu Leu Lys Ser Leu Ile Ser Lys Ser Val
                 560                 565                 570

 Ser Gln Glu Lys Gln Glu Lys Gly Met Ala Asn Leu Ala Gln Leu
                 575                 580                 585

 Glu Ala Leu Tyr Gln Ser Ser Trp Asp Ser Gln Phe Val Ser Gly
                 590                 595                 600

 Gly Glu Asp Cys Phe Phe Ile Asn Gln Phe Cys Glu Val Arg Lys
                 605                 610                 615

 Asp Glu Gln Val Glu Lys Glu Asn Thr Tyr Thr Ser Tyr Leu Asp
                 620                 625                 630

 Lys Phe Phe Ser Arg Lys Glu Asp Thr Glu Met Leu Glu Thr Glu
                 635                 640                 645

 Pro Val Glu Asp Gly Lys Leu Gly Glu Arg Gly His Glu Glu Gly
                 650                 655                 660

 Phe Leu Asn Asn Ser Gly Glu Phe Leu Phe Asn Lys Gln Leu Glu
                 665                 670                 675

 Ser Ile Gly Ile Pro Gln Phe His Ser Pro Val Gly Ser Pro Leu
                 680                 685                 690

 Lys Ser Ile Gln Ala Thr Leu Thr Pro Ser Ala Met Lys Ser Ser
                 695                 700                 705

 Pro Gln Ile Pro His Gln Thr Tyr Ser Ser Ile Leu Lys His Leu
                 710                 715                 720

 Asn


<210> 1589
<211> 1247
<212> DNA
<213> Homo sapien

<400> 1589
 gtaaagctag accgatctcc ggggagcccc ggagtaggcg agcggcggcc 50

 gccagctagt tgagcgcacc ccccgcccgc cccagcggcg ccgcggcggg 100

 cggcgtccag gcggcatgga gaaggacggc ctgtgccgcg ctgaccagca 150

 gtacgaatgc gtggcggaga tcggggaggg cgcctatggg aaggtgttca 200

 aggcccgcga cttgaagaac ggaggccgtt tcgtggcgtt gaagcgcgtg 250

 cgggtgcaga ccggcgagga gggcatgccg ctctccacca tccgcgaggt 300

 ggcggtgctg aggcacctgg agaccttcga gcaccccaac gtggtcaggt 350

 tgtttgatgt gtgcacagtg tcacgaacag acagagaaac caaactaact 400

 ttagtgtttg aacatgtcga tcaagacttg accacttact tggataaagt 450

 tccagagcct ggagtgccca ctgaaaccat aaaggatatg atgtttcagc 500

 ttctccgagg tctggacttt cttcattcac accgagtagt gcatcgcgat 550

 ctaaaaccac agaacattct ggtgaccagc agcggacaaa taaaactcgc 600

 tgacttcggc cttgcccgca tctatagttt ccagatggct ctaacctcag 650

 tggtcgtcac gctgtggtac agagcacccg aagtcttgct ccagtccagc 700

 tacgccaccc ccgtggatct ctggagtgtt ggctgcatat ttgcagaaat 750

 gtttcgtaga aagcctcttt ttcgtggaag ttcagatgtt gatcaactag 800

 gaaaaatctt ggacgtgatt ggactcccag gagaagaaga ctggcctaga 850

 gatgttgccc ttcccaggca ggcttttcat tcaaaatctg cccaaccaat 900

 tgagaagttt gtaacagata tcgatgaact aggcaaagac ctacttctga 950

 agtgtttgac atttaaccca gccaaaagaa tatctgccta cagtgccctg 1000

 tctcacccat acttccagga cctggaaagg tgcaaagaaa acctggattc 1050

 ccacctgccg cccagccaga acacctcgga gctgaataca gcctgaggcc 1100

 tcagcagccg ccttaagctg atcctgcgga gaacaccctt ggtggcttat 1150

 gggtccccct cagcaagccc tacagagctg tggaggattg ctatctggag 1200

 gccttccagc tgctgtcttc tggacaggct ctgcttctcc aaggaaa 1247

<210> 1590
<211> 326
<212> PRT
<213> Homo sapien

<400> 1590
 Met Glu Lys Asp Gly Leu Cys Arg Ala Asp Gln Gln Tyr Glu Cys
   1               5                  10                  15

 Val Ala Glu Ile Gly Glu Gly Ala Tyr Gly Lys Val Phe Lys Ala
                  20                  25                  30

 Arg Asp Leu Lys Asn Gly Gly Arg Phe Val Ala Leu Lys Arg Val
                  35                  40                  45

 Arg Val Gln Thr Gly Glu Glu Gly Met Pro Leu Ser Thr Ile Arg
                  50                  55                  60

 Glu Val Ala Val Leu Arg His Leu Glu Thr Phe Glu His Pro Asn
                  65                  70                  75

 Val Val Arg Leu Phe Asp Val Cys Thr Val Ser Arg Thr Asp Arg
                  80                  85                  90

 Glu Thr Lys Leu Thr Leu Val Phe Glu His Val Asp Gln Asp Leu
                  95                 100                 105

 Thr Thr Tyr Leu Asp Lys Val Pro Glu Pro Gly Val Pro Thr Glu
                 110                 115                 120

 Thr Ile Lys Asp Met Met Phe Gln Leu Leu Arg Gly Leu Asp Phe
                 125                 130                 135

 Leu His Ser His Arg Val Val His Arg Asp Leu Lys Pro Gln Asn
                 140                 145                 150

 Ile Leu Val Thr Ser Ser Gly Gln Ile Lys Leu Ala Asp Phe Gly
                 155                 160                 165

 Leu Ala Arg Ile Tyr Ser Phe Gln Met Ala Leu Thr Ser Val Val
                 170                 175                 180

 Val Thr Leu Trp Tyr Arg Ala Pro Glu Val Leu Leu Gln Ser Ser
                 185                 190                 195

 Tyr Ala Thr Pro Val Asp Leu Trp Ser Val Gly Cys Ile Phe Ala
                 200                 205                 210

 Glu Met Phe Arg Arg Lys Pro Leu Phe Arg Gly Ser Ser Asp Val
                 215                 220                 225

 Asp Gln Leu Gly Lys Ile Leu Asp Val Ile Gly Leu Pro Gly Glu
                 230                 235                 240

 Glu Asp Trp Pro Arg Asp Val Ala Leu Pro Arg Gln Ala Phe His
                 245                 250                 255

 Ser Lys Ser Ala Gln Pro Ile Glu Lys Phe Val Thr Asp Ile Asp
                 260                 265                 270

 Glu Leu Gly Lys Asp Leu Leu Leu Lys Cys Leu Thr Phe Asn Pro
                 275                 280                 285

 Ala Lys Arg Ile Ser Ala Tyr Ser Ala Leu Ser His Pro Tyr Phe
                 290                 295                 300

 Gln Asp Leu Glu Arg Cys Lys Glu Asn Leu Asp Ser His Leu Pro
                 305                 310                 315

 Pro Ser Gln Asn Thr Ser Glu Leu Asn Thr Ala
                 320                 325

<210> 1591
<211> 1444
<212> DNA
<213> Homo sapien

<400> 1591
 tttcattttg ggccgagctg gaggcggcgg ggccgtcccg gaacggctgc 50

 ggccgggcac cccgggagtt aatccgaaag cgccgcaagc cccgcgggcc 100

 ggccgcaccg cacgtgtcac cgagaagctg atgtagagag agacacagaa 150

 ggagacagaa agcaagagac cagagtcccg ggaaagtcct gccgcgcctc 200

 gggacaatta taaaaatgtg gccccctggg tcagcctccc agccaccgcc 250

 ctcacctgcc gcggccacag gtctgcatcc agcggctcgc cctgtgtccc 300

 tgcagtgccg gctcagcatg tgtccagcgc gcagcctcct ccttgtggct 350

 accctggtcc tcctggacca cctcagtttg gccagaaacc tccccgtggc 400

 cactccagac ccaggaatgt tcccatgcct tcaccactcc caaaacctgc 450

 tgagggccgt cagcaacatg ctccagaagg ccagacaaac tctagaattt 500

 tacccttgca cttctgaaga gattgatcat gaagatatca caaaagataa 550

 aaccagcaca gtggaggcct gtttaccatt ggaattaacc aagaatgaga 600

 gttgcctaaa ttccagagag acctctttca taactaatgg gagttgcctg 650

 gcctccagaa agacctcttt tatgatggcc ctgtgcctta gtagtattta 700

 tgaagacttg aagatgtacc aggtggagtt caagaccatg aatgcaaagc 750

 ttctgatgga tcctaagagg cagatctttc tagatcaaaa catgctggca 800

 gttattgatg agctgatgca ggccctgaat ttcaacagtg agactgtgcc 850

 acaaaaatcc tcccttgaag aaccggattt ttataaaact aaaatcaagc 900

 tctgcatact tcttcatgct ttcagaattc gggcagtgac tattgataga 950

 gtgatgagct atctgaatgc ttcctaaaaa gcgaggtccc tccaaaccgt 1000

 tgtcattttt ataaaacttt gaaatgagga aactttgata ggatgtggat 1050

 taagaactag ggagggggaa agaaggatgg gactattaca tccacatgat 1100

 acctctgatc aagtattttt gacatttact gtggataaat tgtttttaag 1150

 ttttcatgaa tgaattgcta agaagggaaa atatccatcc tgaaggtgtt 1200

 tttcattcac tttaatagaa gggcaaatat ttataagcta tttctgtacc 1250

 aaagtgtttg tggaaacaaa catgtaagca taacttattt taaaatattt 1300

 atttatataa cttggtaatc atgaaagcat ctgagctaac ttatatttat 1350

 ttatgttata tttattaaat tatttatcaa gtgtatttga aaaatatttt 1400

 taagtgttct aaaaataaaa gtattgaatt aaagtgaaaa aaaa 1444

<210> 1592
<211> 253
<212> PRT
<213> Homo sapien

<400> 1592
 Met Trp Pro Pro Gly Ser Ala Ser Gln Pro Pro Pro Ser Pro Ala
   1               5                  10                  15

 Ala Ala Thr Gly Leu His Pro Ala Ala Arg Pro Val Ser Leu Gln
                  20                  25                  30

 Cys Arg Leu Ser Met Cys Pro Ala Arg Ser Leu Leu Leu Val Ala
                  35                  40                  45

 Thr Leu Val Leu Leu Asp His Leu Ser Leu Ala Arg Asn Leu Pro
                  50                  55                  60

 Val Ala Thr Pro Asp Pro Gly Met Phe Pro Cys Leu His His Ser
                  65                  70                  75

 Gln Asn Leu Leu Arg Ala Val Ser Asn Met Leu Gln Lys Ala Arg
                  80                  85                  90

 Gln Thr Leu Glu Phe Tyr Pro Cys Thr Ser Glu Glu Ile Asp His
                  95                 100                 105

 Glu Asp Ile Thr Lys Asp Lys Thr Ser Thr Val Glu Ala Cys Leu
                 110                 115                 120

 Pro Leu Glu Leu Thr Lys Asn Glu Ser Cys Leu Asn Ser Arg Glu
                 125                 130                 135

 Thr Ser Phe Ile Thr Asn Gly Ser Cys Leu Ala Ser Arg Lys Thr
                 140                 145                 150

 Ser Phe Met Met Ala Leu Cys Leu Ser Ser Ile Tyr Glu Asp Leu
                 155                 160                 165

 Lys Met Tyr Gln Val Glu Phe Lys Thr Met Asn Ala Lys Leu Leu
                 170                 175                 180

 Met Asp Pro Lys Arg Gln Ile Phe Leu Asp Gln Asn Met Leu Ala
                 185                 190                 195

 Val Ile Asp Glu Leu Met Gln Ala Leu Asn Phe Asn Ser Glu Thr
                 200                 205                 210

 Val Pro Gln Lys Ser Ser Leu Glu Glu Pro Asp Phe Tyr Lys Thr
                 215                 220                 225

 Lys Ile Lys Leu Cys Ile Leu Leu His Ala Phe Arg Ile Arg Ala
                 230                 235                 240

 Val Thr Ile Asp Arg Val Met Ser Tyr Leu Asn Ala Ser
                 245                 250

<210> 1593
<211> 3002
<212> DNA
<213> Homo sapien

<400> 1593
 gccagtcacc ttcagtttct ggagctggcc gtcaacatgt cctttcctaa 50

 ggcgcccttg aaacgattca atgacccttc tggttgtgca ccatctccag 100

 gtgcttatga tgttaaaact ttagaagtat tgaaaggacc agtatccttt 150

 cagaaatcac aaagatttaa acaacaaaaa gaatctaaac aaaatcttaa 200

 tgttgacaaa gatactacct tgcctgcttc agctagaaaa gttaagtctt 250

 cggaatcaaa ggaatctcaa aagaatgata aagatttgaa gatattagag 300

 aaagagattc gtgttcttct acaggaacgt ggtgcccagg acagccggat 350

 ccaggatctg gaaactgagt tggaaaagat ggaagcaagg ctaaatgctg 400

 cactaaggga aaaaacatct ctctctgcaa ataatgctac actggaaaaa 450

 caacttattg aattgaccag gactaatgaa ctactaaaat ctaagttttc 500

 tgaaaatggt aaccagaaga atttgagaat tctaagcttg gagttgatga 550

 aacttagaaa caaaagagaa acaaagatga ggggtatgat ggctaagcaa 600

 gaaggcatgg agatgaagct gcaggtcacc caaaggagtc tcgaagagtc 650

 tcaagggaaa atagcccaac tggagggaaa acttgtttca atagagaaag 700

 aaaagattga tgaaaaatct gaaacagaaa aactcttgga atacatcgaa 750

 gaaattagtt gtgcttcaga tcaagtggaa aaatacaagc tagatattgc 800

 ccagttagaa gaaaatttga aagagaagaa tgatgaaatt ttaagcctta 850

 agcagtctct tgaggagaat attgttatat tatctaaaca agtagaagat 900

 ctaaatgtga aatgtcagct gcttgaaaaa gaaaaagaag accatgtcaa 950

 caggaataga gaacacaacg aaaatctaaa tgcagagatg caaaacttaa 1000

 aacagaagtt tattcttgaa caacaggaac gtgaaaagct tcaacaaaaa 1050

 gaattacaaa ttgattcact tctgcaacaa gagaaagaat tatcttcgag 1100

 tcttcatcag aagctctgtt cttttcaaga ggaaatggtt aaagagaaga 1150

 atctgtttga ggaagaatta aagcaaacac tggatgagct tgataaatta 1200

 cagcaaaagg aggaacaagc tgaaaggctg gtcaagcaat tggaagagga 1250

 agcaaaatct agagctgaag aattaaaact cctagaagaa aagctgaaag 1300

 ggaaggaggc tgaactggag aaaagtagtg ctgctcatac ccaggccacc 1350

 ctgcttttgc aggaaaagta tgacagtatg gtgcaaagcc ttgaagatgt 1400

 tactgctcaa tttgaaagct ataaagcgtt aacagccagt gagatagaag 1450

 atcttaagct ggagaactca tcattacagg aaaaagcggc caaggctggg 1500

 aaaaatgcag aggatgttca gcatcagatt ttggcaactg agagctcaaa 1550

 tcaagaatat gtaaggatgc ttctagatct gcagaccaag tcagcactaa 1600

 aggaaacaga aattaaagaa atcacagttt cttttcttca aaaaataact 1650

 gatttgcaga accaactcaa gcaacaggag gaagacttta gaaaacagct 1700

 ggaagatgaa gaaggaagaa aagctgaaaa agaaaataca acagcagaat 1750

 taactgaaga aattaacaag tggcgtctcc tctatgaaga actatataat 1800

 aaaacaaaac cttttcagct acaactagat gcttttgaag tagaaaaaca 1850

 ggcattgttg aatgaacatg gtgcagctca ggaacagcta aataaaataa 1900

 gagattcata tgctaaatta ttgggtcatc agaatttgaa acaaaaaatc 1950

 aagcatgttg tgaagttgaa agatgaaaat agccaactca aatcggaagt 2000

 atcaaaactc cgctgtcagc ttgctaaaaa aaaacaaagt gagacaaaac 2050

 ttcaagagga attgaataaa gttctaggta tcaaacactt tgatccttca 2100

 aaggcttttc atcatgaaag taaagaaaat tttgccctga agaccccatt 2150

 aaaagaaggc aatacaaact gttaccgagc tcctatggag tgtcaagaat 2200

 catggaagta aacatctgag aaacctgttg aagattattt cattcgtctt 2250

 gttgttattg atgttgctgt tattatattt gacatgggta ttttataatg 2300

 ttgtatttaa ttttaactgc caatccttaa atatgtgaaa ggaacatttt 2350

 ttaccaaagt gtcttttgac attttatttt ttcttgcaaa tacctcctcc 2400

 ctaatgctca cctttatcac ctcattctga accctttcgc tggctttcca 2450

 gcttagaatg catctcatca acttaaaagt cagtatcata ttattatcct 2500

 cctgttctga aaccttagtt tcaagagtct aaaccccaga ttcttcagct 2550

 tgatcctgga ggtcttttct agtctgagct tctttagcta ggctaaaaca 2600

 ccttggcttg ttattgcctc tactttgatt ctgataatgc tcacttggtc 2650

 ctacctatta tccttctact tgtccagttc aaataagaaa taaggacaag 2700

 cctaacttca tagaaacctc tctattttta atcagttgtt taataattta 2750

 caggttctta ggctccatcc tgtttgtatg aaattataat ctgtggattg 2800

 gcctttaagc ctgcattctt aacaaactct tcagttaatt cttagataca 2850

 ctaaaaatct gagaaactct acatgtaact atttcttcag agtttgtcat 2900

 atactgcttg tcatctgcat gtctactcag catttgatta acatttgtgt 2950

 aatatgaaat aaaattacac agtaagtcat ttaaccaaaa aaaaaaaaaa 3000

 aa 3002

<210> 1594
<211> 724
<212> PRT
<213> Homo sapien

<400> 1594
 Met Ser Phe Pro Lys Ala Pro Leu Lys Arg Phe Asn Asp Pro Ser
   1               5                  10                  15

 Gly Cys Ala Pro Ser Pro Gly Ala Tyr Asp Val Lys Thr Leu Glu
                  20                  25                  30

 Val Leu Lys Gly Pro Val Ser Phe Gln Lys Ser Gln Arg Phe Lys
                  35                  40                  45

 Gln Gln Lys Glu Ser Lys Gln Asn Leu Asn Val Asp Lys Asp Thr
                  50                  55                  60

 Thr Leu Pro Ala Ser Ala Arg Lys Val Lys Ser Ser Glu Ser Lys
                  65                  70                  75

 Glu Ser Gln Lys Asn Asp Lys Asp Leu Lys Ile Leu Glu Lys Glu
                  80                  85                  90

 Ile Arg Val Leu Leu Gln Glu Arg Gly Ala Gln Asp Ser Arg Ile
                  95                 100                 105

 Gln Asp Leu Glu Thr Glu Leu Glu Lys Met Glu Ala Arg Leu Asn
                 110                 115                 120

 Ala Ala Leu Arg Glu Lys Thr Ser Leu Ser Ala Asn Asn Ala Thr
                 125                 130                 135

 Leu Glu Lys Gln Leu Ile Glu Leu Thr Arg Thr Asn Glu Leu Leu
                 140                 145                 150

 Lys Ser Lys Phe Ser Glu Asn Gly Asn Gln Lys Asn Leu Arg Ile
                 155                 160                 165

 Leu Ser Leu Glu Leu Met Lys Leu Arg Asn Lys Arg Glu Thr Lys
                 170                 175                 180

 Met Arg Gly Met Met Ala Lys Gln Glu Gly Met Glu Met Lys Leu
                 185                 190                 195

 Gln Val Thr Gln Arg Ser Leu Glu Glu Ser Gln Gly Lys Ile Ala
                 200                 205                 210

 Gln Leu Glu Gly Lys Leu Val Ser Ile Glu Lys Glu Lys Ile Asp
                 215                 220                 225

 Glu Lys Ser Glu Thr Glu Lys Leu Leu Glu Tyr Ile Glu Glu Ile
                 230                 235                 240

 Ser Cys Ala Ser Asp Gln Val Glu Lys Tyr Lys Leu Asp Ile Ala
                 245                 250                 255

 Gln Leu Glu Glu Asn Leu Lys Glu Lys Asn Asp Glu Ile Leu Ser
                 260                 265                 270

 Leu Lys Gln Ser Leu Glu Glu Asn Ile Val Ile Leu Ser Lys Gln
                 275                 280                 285

 Val Glu Asp Leu Asn Val Lys Cys Gln Leu Leu Glu Lys Glu Lys
                 290                 295                 300

 Glu Asp His Val Asn Arg Asn Arg Glu His Asn Glu Asn Leu Asn
                 305                 310                 315

 Ala Glu Met Gln Asn Leu Lys Gln Lys Phe Ile Leu Glu Gln Gln
                 320                 325                 330

 Glu Arg Glu Lys Leu Gln Gln Lys Glu Leu Gln Ile Asp Ser Leu
                 335                 340                 345

 Leu Gln Gln Glu Lys Glu Leu Ser Ser Ser Leu His Gln Lys Leu
                 350                 355                 360

 Cys Ser Phe Gln Glu Glu Met Val Lys Glu Lys Asn Leu Phe Glu
                 365                 370                 375

 Glu Glu Leu Lys Gln Thr Leu Asp Glu Leu Asp Lys Leu Gln Gln
                 380                 385                 390

 Lys Glu Glu Gln Ala Glu Arg Leu Val Lys Gln Leu Glu Glu Glu
                 395                 400                 405

 Ala Lys Ser Arg Ala Glu Glu Leu Lys Leu Leu Glu Glu Lys Leu
                 410                 415                 420

 Lys Gly Lys Glu Ala Glu Leu Glu Lys Ser Ser Ala Ala His Thr
                 425                 430                 435

 Gln Ala Thr Leu Leu Leu Gln Glu Lys Tyr Asp Ser Met Val Gln
                 440                 445                 450

 Ser Leu Glu Asp Val Thr Ala Gln Phe Glu Ser Tyr Lys Ala Leu
                 455                 460                 465

 Thr Ala Ser Glu Ile Glu Asp Leu Lys Leu Glu Asn Ser Ser Leu
                 470                 475                 480

 Gln Glu Lys Ala Ala Lys Ala Gly Lys Asn Ala Glu Asp Val Gln
                 485                 490                 495

 His Gln Ile Leu Ala Thr Glu Ser Ser Asn Gln Glu Tyr Val Arg
                 500                 505                 510

 Met Leu Leu Asp Leu Gln Thr Lys Ser Ala Leu Lys Glu Thr Glu
                 515                 520                 525

 Ile Lys Glu Ile Thr Val Ser Phe Leu Gln Lys Ile Thr Asp Leu
                 530                 535                 540

 Gln Asn Gln Leu Lys Gln Gln Glu Glu Asp Phe Arg Lys Gln Leu
                 545                 550                 555

 Glu Asp Glu Glu Gly Arg Lys Ala Glu Lys Glu Asn Thr Thr Ala
                 560                 565                 570

 Glu Leu Thr Glu Glu Ile Asn Lys Trp Arg Leu Leu Tyr Glu Glu
                 575                 580                 585

 Leu Tyr Asn Lys Thr Lys Pro Phe Gln Leu Gln Leu Asp Ala Phe
                 590                 595                 600

 Glu Val Glu Lys Gln Ala Leu Leu Asn Glu His Gly Ala Ala Gln
                 605                 610                 615

 Glu Gln Leu Asn Lys Ile Arg Asp Ser Tyr Ala Lys Leu Leu Gly
                 620                 625                 630

 His Gln Asn Leu Lys Gln Lys Ile Lys His Val Val Lys Leu Lys
                 635                 640                 645

 Asp Glu Asn Ser Gln Leu Lys Ser Glu Val Ser Lys Leu Arg Cys
                 650                 655                 660

 Gln Leu Ala Lys Lys Lys Gln Ser Glu Thr Lys Leu Gln Glu Glu
                 665                 670                 675

 Leu Asn Lys Val Leu Gly Ile Lys His Phe Asp Pro Ser Lys Ala
                 680                 685                 690

 Phe His His Glu Ser Lys Glu Asn Phe Ala Leu Lys Thr Pro Leu
                 695                 700                 705

 Lys Glu Gly Asn Thr Asn Cys Tyr Arg Ala Pro Met Glu Cys Gln
                 710                 715                 720

 Glu Ser Trp Lys


<210> 1595
<211> 2578
<212> DNA
<213> Homo sapien

<400> 1595
 ggaggaggaa agaggaggac atggtctccg aggaggagga ggaggaggac 50

 ggcgacgccg aggagaccca ggattctgag gacgacgagg aggatgagat 100

 ggaagaggac gacgatgact ccgattatcc ggaggagatg gaagacgacg 150

 acgacgacgc cagttactgc acggaaagca gcttcaggag ccatagtacc 200

 tacagcagca ctccaggtag gcgaaaacca agagtacatc ggcctcgttc 250

 tcctatattg gaagaaaaag acatcccgcc ccttgaattt cccaagtcct 300

 ctgaggattt aatggtgcct aatgagcata taatgaatgt cattgccatt 350

 tacgaggtac tgcggaactt tggcactgtt ttgagattat ctccttttcg 400

 ctttgaggac ttttgtgcag ctctggtgag ccaagagcag tgcacactca 450

 tggcagagat gcatgttgtg cttttgaaag cagttctgcg tgaagaagac 500

 acttccaata ctacctttgg acctgctgat ctgaaagata gcgttaattc 550

 cacactgtat ttcatagatg ggatgacgtg gccagaggtg ctgcgggtgt 600

 actgtgagag tgataaggag taccatcacg ttcttcctta ccaagaggca 650

 gaggactacc catatggacc agtagagaac aagatcaaag ttctacagtt 700

 tctagtcgat cagtttctta caacaaatat tgctcgagag gaattgatgt 750

 ctgaaggggt gatacagtat gatgaccatt gtagggtttg tcacaaactt 800

 ggggatttgc tttgctgtga gacatgttca gcagtatacc atttggaatg 850

 tgtgaagcca cctcttgagg aggtgccaga ggacgagtgg cagtgtgaag 900

 tctgtgtagc acacaaggtg cctggtgtga ctgactgtgt tgctgaaatc 950

 caaaaaaata aaccatatat tcgacatgaa cctattggat atgatagaag 1000

 tcggaggaaa tactggttct tgaaccgaag actcataata gaagaagata 1050

 cagaaaatga aaatgaaaag aaaatttggt attacagcac aaaggtccaa 1100

 cttgcagaat taattgactg tctagacaaa gattattggg aagcagaact 1150

 ctgcaaaatt ctagaagaaa tgcgtgaaga aatccaccga cacatggaca 1200

 taactgaaga cctgaccaat aaggctcggg gcagtaacaa atcctttctg 1250

 gcggcagcta atgaagaaat tttggaatcc ataagagcca aaaagggaga 1300

 cattgataat gttaaaagcc cagaagaaac agaaaaagac aagaatgaga 1350

 ctgagaatga ctctaaagat gctgagaaaa acagagaaga atttgaagac 1400

 cagtcccttg aaaaagacag tgacgacaaa acaccagatg atgaccctga 1450

 gcaaggaaaa tctgaggagc caacagaagt tggggataaa ggtaactctg 1500

 tgtcagcaaa tcttggcgac aacacaacaa atgcaacttc agaagagact 1550

 agtccctctg aagggaggag ccctgtgggg tgtctctcag aaacccccga 1600

 tagcagcaac atggcagaga agaaggtggc atctgagctc ccccaggatg 1650

 tgccagaaga acctaacaag acatgtgaga gcagtaacac tagtgctacc 1700

 actacctcca tccagcctaa tctggaaaac agtaacagca gcagtgaact 1750

 aaattcttcc cagagtgaat ctgctaaggc agctgatgat cctgaaaatg 1800

 gagaaagaga atctcataca cctgtctcta ttcaggaaga gatagtaggt 1850

 gatttcacat cggagaagtc caccggggag ctaagtgaat ctcctggagc 1900

 tggaaaagga gcatctggct caactcgaat catcaccaga ttgcggaatc 1950

 cagatagcaa acttagtcag ctgaagagcc agcaggtggc agccgctgca 2000

 catgaagcaa ataaattatt taaggagggc aaagaggtac tggtagttaa 2050

 ctctcaagga gaaatttcac ggttgagcac caaaaaggaa gtgatcatga 2100

 aaggaaatat caacaattat tttaaattgg gtcaagaagg gaagtatcgc 2150

 gtctaccaca atcaatactc caccaattca tttgctttga ataagcacca 2200

 gcacagagaa gaccatgata agagaaggca tcttgcacat aagttctgtc 2250

 tgactccagc aggagagttc aaatggaacg gttctgtcca tgggtccaaa 2300

 gttcttacca tatctactct gagactgact atcacccaat tagaaacaac 2350

 atcccttcat ccttccttca tcccaactgg gcatcacata gggcaaattg 2400

 gatcaaggca gttcagatgt gtagcaaacc cagagaattt gcattggctt 2450

 tagccatttt ggagtgtgca gttaaaccag ttgtgatgct accaatatgg 2500

 cgagaatctt taggacatac caggttacac cggatgacat caattgaaag 2550

 agaagaaaag gagaaagtca aaaaaaaa 2578

<210> 1596
<211> 810
<212> PRT
<213> Homo sapien

<400> 1596
 Met Val Ser Glu Glu Glu Glu Glu Glu Asp Gly Asp Ala Glu Glu
   1               5                  10                  15

 Thr Gln Asp Ser Glu Asp Asp Glu Glu Asp Glu Met Glu Glu Asp
                  20                  25                  30

 Asp Asp Asp Ser Asp Tyr Pro Glu Glu Met Glu Asp Asp Asp Asp
                  35                  40                  45

 Asp Ala Ser Tyr Cys Thr Glu Ser Ser Phe Arg Ser His Ser Thr
                  50                  55                  60

 Tyr Ser Ser Thr Pro Gly Arg Arg Lys Pro Arg Val His Arg Pro
                  65                  70                  75

 Arg Ser Pro Ile Leu Glu Glu Lys Asp Ile Pro Pro Leu Glu Phe
                  80                  85                  90

 Pro Lys Ser Ser Glu Asp Leu Met Val Pro Asn Glu His Ile Met
                  95                 100                 105

 Asn Val Ile Ala Ile Tyr Glu Val Leu Arg Asn Phe Gly Thr Val
                 110                 115                 120

 Leu Arg Leu Ser Pro Phe Arg Phe Glu Asp Phe Cys Ala Ala Leu
                 125                 130                 135

 Val Ser Gln Glu Gln Cys Thr Leu Met Ala Glu Met His Val Val
                 140                 145                 150

 Leu Leu Lys Ala Val Leu Arg Glu Glu Asp Thr Ser Asn Thr Thr
                 155                 160                 165

 Phe Gly Pro Ala Asp Leu Lys Asp Ser Val Asn Ser Thr Leu Tyr
                 170                 175                 180

 Phe Ile Asp Gly Met Thr Trp Pro Glu Val Leu Arg Val Tyr Cys
                 185                 190                 195

 Glu Ser Asp Lys Glu Tyr His His Val Leu Pro Tyr Gln Glu Ala
                 200                 205                 210

 Glu Asp Tyr Pro Tyr Gly Pro Val Glu Asn Lys Ile Lys Val Leu
                 215                 220                 225

 Gln Phe Leu Val Asp Gln Phe Leu Thr Thr Asn Ile Ala Arg Glu
                 230                 235                 240

 Glu Leu Met Ser Glu Gly Val Ile Gln Tyr Asp Asp His Cys Arg
                 245                 250                 255

 Val Cys His Lys Leu Gly Asp Leu Leu Cys Cys Glu Thr Cys Ser
                 260                 265                 270

 Ala Val Tyr His Leu Glu Cys Val Lys Pro Pro Leu Glu Glu Val
                 275                 280                 285

 Pro Glu Asp Glu Trp Gln Cys Glu Val Cys Val Ala His Lys Val
                 290                 295                 300

 Pro Gly Val Thr Asp Cys Val Ala Glu Ile Gln Lys Asn Lys Pro
                 305                 310                 315

 Tyr Ile Arg His Glu Pro Ile Gly Tyr Asp Arg Ser Arg Arg Lys
                 320                 325                 330

 Tyr Trp Phe Leu Asn Arg Arg Leu Ile Ile Glu Glu Asp Thr Glu
                 335                 340                 345

 Asn Glu Asn Glu Lys Lys Ile Trp Tyr Tyr Ser Thr Lys Val Gln
                 350                 355                 360

 Leu Ala Glu Leu Ile Asp Cys Leu Asp Lys Asp Tyr Trp Glu Ala
                 365                 370                 375

 Glu Leu Cys Lys Ile Leu Glu Glu Met Arg Glu Glu Ile His Arg
                 380                 385                 390

 His Met Asp Ile Thr Glu Asp Leu Thr Asn Lys Ala Arg Gly Ser
                 395                 400                 405

 Asn Lys Ser Phe Leu Ala Ala Ala Asn Glu Glu Ile Leu Glu Ser
                 410                 415                 420

 Ile Arg Ala Lys Lys Gly Asp Ile Asp Asn Val Lys Ser Pro Glu
                 425                 430                 435

 Glu Thr Glu Lys Asp Lys Asn Glu Thr Glu Asn Asp Ser Lys Asp
                 440                 445                 450

 Ala Glu Lys Asn Arg Glu Glu Phe Glu Asp Gln Ser Leu Glu Lys
                 455                 460                 465

 Asp Ser Asp Asp Lys Thr Pro Asp Asp Asp Pro Glu Gln Gly Lys
                 470                 475                 480

 Ser Glu Glu Pro Thr Glu Val Gly Asp Lys Gly Asn Ser Val Ser
                 485                 490                 495

 Ala Asn Leu Gly Asp Asn Thr Thr Asn Ala Thr Ser Glu Glu Thr
                 500                 505                 510

 Ser Pro Ser Glu Gly Arg Ser Pro Val Gly Cys Leu Ser Glu Thr
                 515                 520                 525

 Pro Asp Ser Ser Asn Met Ala Glu Lys Lys Val Ala Ser Glu Leu
                 530                 535                 540

 Pro Gln Asp Val Pro Glu Glu Pro Asn Lys Thr Cys Glu Ser Ser
                 545                 550                 555

 Asn Thr Ser Ala Thr Thr Thr Ser Ile Gln Pro Asn Leu Glu Asn
                 560                 565                 570

 Ser Asn Ser Ser Ser Glu Leu Asn Ser Ser Gln Ser Glu Ser Ala
                 575                 580                 585

 Lys Ala Ala Asp Asp Pro Glu Asn Gly Glu Arg Glu Ser His Thr
                 590                 595                 600

 Pro Val Ser Ile Gln Glu Glu Ile Val Gly Asp Phe Thr Ser Glu
                 605                 610                 615

 Lys Ser Thr Gly Glu Leu Ser Glu Ser Pro Gly Ala Gly Lys Gly
                 620                 625                 630

 Ala Ser Gly Ser Thr Arg Ile Ile Thr Arg Leu Arg Asn Pro Asp
                 635                 640                 645

 Ser Lys Leu Ser Gln Leu Lys Ser Gln Gln Val Ala Ala Ala Ala
                 650                 655                 660

 His Glu Ala Asn Lys Leu Phe Lys Glu Gly Lys Glu Val Leu Val
                 665                 670                 675

 Val Asn Ser Gln Gly Glu Ile Ser Arg Leu Ser Thr Lys Lys Glu
                 680                 685                 690

 Val Ile Met Lys Gly Asn Ile Asn Asn Tyr Phe Lys Leu Gly Gln
                 695                 700                 705

 Glu Gly Lys Tyr Arg Val Tyr His Asn Gln Tyr Ser Thr Asn Ser
                 710                 715                 720

 Phe Ala Leu Asn Lys His Gln His Arg Glu Asp His Asp Lys Arg
                 725                 730                 735

 Arg His Leu Ala His Lys Phe Cys Leu Thr Pro Ala Gly Glu Phe
                 740                 745                 750

 Lys Trp Asn Gly Ser Val His Gly Ser Lys Val Leu Thr Ile Ser
                 755                 760                 765

 Thr Leu Arg Leu Thr Ile Thr Gln Leu Glu Thr Thr Ser Leu His
                 770                 775                 780

 Pro Ser Phe Ile Pro Thr Gly His His Ile Gly Gln Ile Gly Ser
                 785                 790                 795

 Arg Gln Phe Arg Cys Val Ala Asn Pro Glu Asn Leu His Trp Leu
                 800                 805                 810

<210> 1597
<211> 4246
<212> DNA
<213> Homo sapien

<400> 1597
 gatgagattg atgattcttt ctcctggaaa acctttcatc acagagattc 50

 atctcagcat taaagggcag tatttaaagt cagttggcaa gcagtggaat 100

 aagatttttg taaagaaacc ttgtgcagca tggattctct accagatgaa 150

 ttttttgtga ggcatcctgc tgtggaggat cagaggaagg aagaaactga 200

 gaataagcta gaaaaatcat ctggtcaact gaacaaacag gaaaatgaca 250

 tacctactga tcttgtccct gttaacctac tattagaagt gaagaagtta 300

 ttaaatgcaa ttaatactct accaaaaggt gtggttcctc acattaagaa 350

 gttcttacaa gaagattttt ccttccaaac tatgcagaga gaagttgcag 400

 ctaacagcca gaatggtgag gaaattgttc ctgctttgac tttacgtttc 450

 ttgattacac agctagaagc agcacttagg aacattcaag ctggcaatta 500

 taccgcacac cagattaata ttggttatta tttgacatta ctgtttttat 550

 atggagtagc actcactgaa agaggaaaga aagaggatta tacagaagct 600

 gagaataaat ttctggtgat gaagatgatg atccaagaaa atgaaatttg 650

 tgaaaacttt atgtctttag tttattttgg acgtggttta ctgcgatgtg 700

 ctcaaaagag atataatgga ggactgctag aatttcataa aagcttacaa 750

 gaaattggag acaaaaatga ccattggttt gacatagatc ctacagaaga 800

 tgaagattta cctacaactt ttaaagatct tcttaataat tttatcaaga 850

 caactgaaag caatataatg aagcagacga tttgtagtta cctagattgt 900

 gaacgatctt gtgaagctga cattttgaag aacaccagtt ataagggatt 950

 ttttcagtta atgtgcagta aaagttgctg tgtttatttc cataaaattt 1000

 gctggaaaaa gttcaagaat ttaaagtatc caggtgaaaa tgatcagagt 1050

 tttagtggga aaaaatgttt gaaggaagga tgtacaggtg acatggtaag 1100

 gatgctgcaa tgtgatgtac ctggaattgt taaaattttg tttgaagttg 1150

 tgagaaagga tgaatatatc accattgaaa atttaggagc aagttataga 1200

 aagttgatat ctctgaaaat aactgatact gatataagac cgaagatcag 1250

 tttaaaattt aatacaaaag atgaaatgcc tatcttcaag cttgattata 1300

 attatttcta tcatctgctt catataatta ttatttctgg tactgacatt 1350

 gttcgacaaa tatttgatga ggctatgcca cctcctcttt tgaaaaaaga 1400

 gcttcttata cacaagaatg tgctggaatc ctactacaac catctttgga 1450

 ccaatcatcc tttgggtgga tcatggcatc tgctttatcc tcctaacaag 1500

 gagttaccgc aatccaaaca gtttgactta tgcctcctgt tagctcttat 1550

 aaaacattta aatgtgttcc ctgcacccaa aaaaggatgg aatatggaac 1600

 cgccatcttc tgacatctct aaatctgcag acatcctgag actgtgcaaa 1650

 tacagggata tcctccttag tgagattttg atgaatggtc tcactgagtc 1700

 acagttcaat tcaatttgga aaaaagtttc agatattctt ctgcgccttg 1750

 ggatgatgca agaggatatt gacaaagtga aggagaatcc cattgagaat 1800

 atctcccttg attaccatca gctatctgtc tacctaggca taccagtacc 1850

 agaaatcata cagaggatgt tatcctgcta tcaacaagga attgctctac 1900

 agtcaataac aggcagtcag cgtattgaaa tagaagagtt acagaatgag 1950

 gaagaagaac taagtccacc tctcatggag tacaatataa atgtgaaatc 2000

 acaccctgag atacagtttg cagaaattaa taaagatggg acctcaatac 2050

 ccagtgaatc ttcaacagaa tctcttaaag atctccagga agttaagagt 2100

 aaacaaagga aaaagaagaa gactaagaat aaaaagaata aagactcaaa 2150

 agaagaccaa gtcccatatg tggtagaaaa ggaagagcag ttgaggaaag 2200

 aacaagcaaa tccacactca gtcagtagac ttataaaaga tgatgcaagt 2250

 gatgttcaag aggattctgc aatggaagac aagttctata gcctggatga 2300

 attgcatatt ctggacatga tagagcaggg ctcagctggc aaagtaacta 2350

 cagactatgg agaaactgaa aaggaaaggc ttgctcgtca aaggcagctt 2400

 tataaattgc actatcagtg tgaagatttc aaaagacagt tgagaacagt 2450

 gacttttcgg tggcaagaaa accaaatgca gattaaaaag aaagacaaaa 2500

 ttatcgcatc tcttaatcaa caagttgctt ttggaatcaa taaggtttcc 2550

 aaattacagc gtcaaatcca tgctaaagat aatgaaatca agaaccttaa 2600

 agagcaactt tctatgaaaa gatctcagtg ggaaatggaa aaacataatc 2650

 tggaaagcac aatgaaaaca tacgtaagca aactgaacgc agaaactagc 2700

 agagctttaa cagccgaggt gtatttctta cagtgtcgta gggattttgg 2750

 tttgcttcat ctagagcaga ctgaaaagga atgtctcaat cagcttgcca 2800

 gggtgactca catggcagca agcaacctag aatcacttca attaaaggct 2850

 gcggtagaca gttggaatgc cattgtggca gatgttagaa acaagattgc 2900

 attcctcagg acacagtaca atgaacaaat aaacaaagtc aagcaaggat 2950

 ttgccttgag taccttgcct ccagtccagc ttcctcctcc accacccagt 3000

 cctgagatac tgatgcagca gttcttagga agaccccttg tgaaagaatc 3050

 tttctttaga cccatactta ctgttcctca aatgcctgca gtttgcccgg 3100

 gagtcgtctc tgcaactggc caacctagag cccccctgat gactggcata 3150

 gcctgggctc tgccagcgcc tgtgggagac gctgtgcctc ccagtgcagg 3200

 tctgcggagt gatccctcca tcatgaattg ggagagaatt acagacaggc 3250

 tgaaaactgc ctttccacag caaaccagaa aggaacttac agatttctta 3300

 cggaaattga aggatgctta tggaaaatcc ttgtctgaac tgacatttga 3350

 tgaaattgtt tgcaagattt cccagtttat tgaccccaaa aagtctcaga 3400

 gtcaaggaaa atcagtgtca aatgttaatt gtgtttcacc tagtcattct 3450

 ccatcacagc ctgatgctgc ccagccccca aaaccagcct ggaggccact 3500

 cacttcacag ggtcctgcca catgggaagg agccagtaat ccagatgagg 3550

 aagaggaaga agaagagcct tgtgtgatct gtcatgagaa tctgtctcca 3600

 gaaaatcttt cagttttgcc ttgcgctcac aaattccatg ctcagtgcat 3650

 tagaccatgg ttgatgcaac aggggacatg tccaacgtgc agactccacg 3700

 ttttgctacc agaagaattc cctggtcacc ccagccggca gttgcccaag 3750

 atctgataca aggtcggggt gtctatgcaa aggaagctca gttttctttt 3800

 attatgagct gcttgtttga gtggtgtaaa actatgtgct cttcaatata 3850

 gtgctaaaga agccagctaa ttttatcaaa gcagcagcca aagaagtcag 3900

 gacaaatctt caggacttgt gaaatgaact gaaagagctt gaagcagatg 3950

 gaattttaat agttacacta tatatgctct tagtaggttt ttttcttgta 4000

 gtggaaacat aactgttagc atatttctta ggatgttttt tcttgtcttt 4050

 ttaaattctt atttcactca tcctttactc tcccctcaag tattctacac 4100

 tttaatttcc tgaaataaat ttaaggaaaa gggaaatagt aaagaagtag 4150

 gaatgggtgc agcacaccag catggcacat gaatacacat gtaactaacc 4200

 tgcacattgt gcacatgtac cctaaaactt aaagtataat aataat 4246

<210> 1598
<211> 1208
<212> PRT
<213> Homo sapien

<400> 1598
 Met Asp Ser Leu Pro Asp Glu Phe Phe Val Arg His Pro Ala Val
   1               5                  10                  15

 Glu Asp Gln Arg Lys Glu Glu Thr Glu Asn Lys Leu Glu Lys Ser
                  20                  25                  30

 Ser Gly Gln Leu Asn Lys Gln Glu Asn Asp Ile Pro Thr Asp Leu
                  35                  40                  45

 Val Pro Val Asn Leu Leu Leu Glu Val Lys Lys Leu Leu Asn Ala
                  50                  55                  60

 Ile Asn Thr Leu Pro Lys Gly Val Val Pro His Ile Lys Lys Phe
                  65                  70                  75

 Leu Gln Glu Asp Phe Ser Phe Gln Thr Met Gln Arg Glu Val Ala
                  80                  85                  90

 Ala Asn Ser Gln Asn Gly Glu Glu Ile Val Pro Ala Leu Thr Leu
                  95                 100                 105

 Arg Phe Leu Ile Thr Gln Leu Glu Ala Ala Leu Arg Asn Ile Gln
                 110                 115                 120

 Ala Gly Asn Tyr Thr Ala His Gln Ile Asn Ile Gly Tyr Tyr Leu
                 125                 130                 135

 Thr Leu Leu Phe Leu Tyr Gly Val Ala Leu Thr Glu Arg Gly Lys
                 140                 145                 150

 Lys Glu Asp Tyr Thr Glu Ala Glu Asn Lys Phe Leu Val Met Lys
                 155                 160                 165

 Met Met Ile Gln Glu Asn Glu Ile Cys Glu Asn Phe Met Ser Leu
                 170                 175                 180

 Val Tyr Phe Gly Arg Gly Leu Leu Arg Cys Ala Gln Lys Arg Tyr
                 185                 190                 195

 Asn Gly Gly Leu Leu Glu Phe His Lys Ser Leu Gln Glu Ile Gly
                 200                 205                 210

 Asp Lys Asn Asp His Trp Phe Asp Ile Asp Pro Thr Glu Asp Glu
                 215                 220                 225

 Asp Leu Pro Thr Thr Phe Lys Asp Leu Leu Asn Asn Phe Ile Lys
                 230                 235                 240

 Thr Thr Glu Ser Asn Ile Met Lys Gln Thr Ile Cys Ser Tyr Leu
                 245                 250                 255

 Asp Cys Glu Arg Ser Cys Glu Ala Asp Ile Leu Lys Asn Thr Ser
                 260                 265                 270

 Tyr Lys Gly Phe Phe Gln Leu Met Cys Ser Lys Ser Cys Cys Val
                 275                 280                 285

 Tyr Phe His Lys Ile Cys Trp Lys Lys Phe Lys Asn Leu Lys Tyr
                 290                 295                 300

 Pro Gly Glu Asn Asp Gln Ser Phe Ser Gly Lys Lys Cys Leu Lys
                 305                 310                 315

 Glu Gly Cys Thr Gly Asp Met Val Arg Met Leu Gln Cys Asp Val
                 320                 325                 330

 Pro Gly Ile Val Lys Ile Leu Phe Glu Val Val Arg Lys Asp Glu
                 335                 340                 345

 Tyr Ile Thr Ile Glu Asn Leu Gly Ala Ser Tyr Arg Lys Leu Ile
                 350                 355                 360

 Ser Leu Lys Ile Thr Asp Thr Asp Ile Arg Pro Lys Ile Ser Leu
                 365                 370                 375

 Lys Phe Asn Thr Lys Asp Glu Met Pro Ile Phe Lys Leu Asp Tyr
                 380                 385                 390

 Asn Tyr Phe Tyr His Leu Leu His Ile Ile Ile Ile Ser Gly Thr
                 395                 400                 405

 Asp Ile Val Arg Gln Ile Phe Asp Glu Ala Met Pro Pro Pro Leu
                 410                 415                 420

 Leu Lys Lys Glu Leu Leu Ile His Lys Asn Val Leu Glu Ser Tyr
                 425                 430                 435

 Tyr Asn His Leu Trp Thr Asn His Pro Leu Gly Gly Ser Trp His
                 440                 445                 450

 Leu Leu Tyr Pro Pro Asn Lys Glu Leu Pro Gln Ser Lys Gln Phe
                 455                 460                 465

 Asp Leu Cys Leu Leu Leu Ala Leu Ile Lys His Leu Asn Val Phe
                 470                 475                 480

 Pro Ala Pro Lys Lys Gly Trp Asn Met Glu Pro Pro Ser Ser Asp
                 485                 490                 495

 Ile Ser Lys Ser Ala Asp Ile Leu Arg Leu Cys Lys Tyr Arg Asp
                 500                 505                 510

 Ile Leu Leu Ser Glu Ile Leu Met Asn Gly Leu Thr Glu Ser Gln
                 515                 520                 525

 Phe Asn Ser Ile Trp Lys Lys Val Ser Asp Ile Leu Leu Arg Leu
                 530                 535                 540

 Gly Met Met Gln Glu Asp Ile Asp Lys Val Lys Glu Asn Pro Ile
                 545                 550                 555

 Glu Asn Ile Ser Leu Asp Tyr His Gln Leu Ser Val Tyr Leu Gly
                 560                 565                 570

 Ile Pro Val Pro Glu Ile Ile Gln Arg Met Leu Ser Cys Tyr Gln
                 575                 580                 585

 Gln Gly Ile Ala Leu Gln Ser Ile Thr Gly Ser Gln Arg Ile Glu
                 590                 595                 600

 Ile Glu Glu Leu Gln Asn Glu Glu Glu Glu Leu Ser Pro Pro Leu
                 605                 610                 615

 Met Glu Tyr Asn Ile Asn Val Lys Ser His Pro Glu Ile Gln Phe
                 620                 625                 630

 Ala Glu Ile Asn Lys Asp Gly Thr Ser Ile Pro Ser Glu Ser Ser
                 635                 640                 645

 Thr Glu Ser Leu Lys Asp Leu Gln Glu Val Lys Ser Lys Gln Arg
                 650                 655                 660

 Lys Lys Lys Lys Thr Lys Asn Lys Lys Asn Lys Asp Ser Lys Glu
                 665                 670                 675

 Asp Gln Val Pro Tyr Val Val Glu Lys Glu Glu Gln Leu Arg Lys
                 680                 685                 690

 Glu Gln Ala Asn Pro His Ser Val Ser Arg Leu Ile Lys Asp Asp
                 695                 700                 705

 Ala Ser Asp Val Gln Glu Asp Ser Ala Met Glu Asp Lys Phe Tyr
                 710                 715                 720

 Ser Leu Asp Glu Leu His Ile Leu Asp Met Ile Glu Gln Gly Ser
                 725                 730                 735

 Ala Gly Lys Val Thr Thr Asp Tyr Gly Glu Thr Glu Lys Glu Arg
                 740                 745                 750

 Leu Ala Arg Gln Arg Gln Leu Tyr Lys Leu His Tyr Gln Cys Glu
                 755                 760                 765

 Asp Phe Lys Arg Gln Leu Arg Thr Val Thr Phe Arg Trp Gln Glu
                 770                 775                 780

 Asn Gln Met Gln Ile Lys Lys Lys Asp Lys Ile Ile Ala Ser Leu
                 785                 790                 795

 Asn Gln Gln Val Ala Phe Gly Ile Asn Lys Val Ser Lys Leu Gln
                 800                 805                 810

 Arg Gln Ile His Ala Lys Asp Asn Glu Ile Lys Asn Leu Lys Glu
                 815                 820                 825

 Gln Leu Ser Met Lys Arg Ser Gln Trp Glu Met Glu Lys His Asn
                 830                 835                 840

 Leu Glu Ser Thr Met Lys Thr Tyr Val Ser Lys Leu Asn Ala Glu
                 845                 850                 855

 Thr Ser Arg Ala Leu Thr Ala Glu Val Tyr Phe Leu Gln Cys Arg
                 860                 865                 870

 Arg Asp Phe Gly Leu Leu His Leu Glu Gln Thr Glu Lys Glu Cys
                 875                 880                 885

 Leu Asn Gln Leu Ala Arg Val Thr His Met Ala Ala Ser Asn Leu
                 890                 895                 900

 Glu Ser Leu Gln Leu Lys Ala Ala Val Asp Ser Trp Asn Ala Ile
                 905                 910                 915

 Val Ala Asp Val Arg Asn Lys Ile Ala Phe Leu Arg Thr Gln Tyr
                 920                 925                 930

 Asn Glu Gln Ile Asn Lys Val Lys Gln Gly Phe Ala Leu Ser Thr
                 935                 940                 945

 Leu Pro Pro Val Gln Leu Pro Pro Pro Pro Pro Ser Pro Glu Ile
                 950                 955                 960

 Leu Met Gln Gln Phe Leu Gly Arg Pro Leu Val Lys Glu Ser Phe
                 965                 970                 975

 Phe Arg Pro Ile Leu Thr Val Pro Gln Met Pro Ala Val Cys Pro
                 980                 985                 990

 Gly Val Val Ser Ala Thr Gly Gln Pro Arg Ala Pro Leu Met Thr
                 995                1000                1005

 Gly Ile Ala Trp Ala Leu Pro Ala Pro Val Gly Asp Ala Val Pro
                1010                1015                1020

 Pro Ser Ala Gly Leu Arg Ser Asp Pro Ser Ile Met Asn Trp Glu
                1025                1030                1035

 Arg Ile Thr Asp Arg Leu Lys Thr Ala Phe Pro Gln Gln Thr Arg
                1040                1045                1050

 Lys Glu Leu Thr Asp Phe Leu Arg Lys Leu Lys Asp Ala Tyr Gly
                1055                1060                1065

 Lys Ser Leu Ser Glu Leu Thr Phe Asp Glu Ile Val Cys Lys Ile
                1070                1075                1080

 Ser Gln Phe Ile Asp Pro Lys Lys Ser Gln Ser Gln Gly Lys Ser
                1085                1090                1095

 Val Ser Asn Val Asn Cys Val Ser Pro Ser His Ser Pro Ser Gln
                1100                1105                1110

 Pro Asp Ala Ala Gln Pro Pro Lys Pro Ala Trp Arg Pro Leu Thr
                1115                1120                1125

 Ser Gln Gly Pro Ala Thr Trp Glu Gly Ala Ser Asn Pro Asp Glu
                1130                1135                1140

 Glu Glu Glu Glu Glu Glu Pro Cys Val Ile Cys His Glu Asn Leu
                1145                1150                1155

 Ser Pro Glu Asn Leu Ser Val Leu Pro Cys Ala His Lys Phe His
                1160                1165                1170

 Ala Gln Cys Ile Arg Pro Trp Leu Met Gln Gln Gly Thr Cys Pro
                1175                1180                1185

 Thr Cys Arg Leu His Val Leu Leu Pro Glu Glu Phe Pro Gly His
                1190                1195                1200

 Pro Ser Arg Gln Leu Pro Lys Ile
                1205

<210> 1599
<211> 4246
<212> DNA
<213> Homo sapien

<400> 1599
 gatgagattg atgattcttt ctcctggaaa acctttcatc acagagattc 50

 atctcagcat taaagggcag tatttaaagt cagttggcaa gcagtggaat 100

 aagatttttg taaagaaacc ttgtgcagca tggattctct accagatgaa 150

 ttttttgtga ggcatcctgc tgtggaggat cagaggaagg aagaaactga 200

 gaataagcta gaaaaatcat ctggtcaact gaacaaacag gaaaatgaca 250

 tacctactga tcttgtccct gttaacctac tattagaagt gaagaagtta 300

 ttaaatgcaa ttaatactct accaaaaggt gtggttcctc acattaagaa 350

 gttcttacaa gaagattttt ccttccaaac tatgcagaga gaagttgcag 400

 ctaacagcca gaatggtgag gaaattgttc ctgctttgac tttacgtttc 450

 ttgattacac agctagaagc agcacttagg aacattcaag ctggcaatta 500

 taccgcacac cagattaata ttggttatta tttgacatta ctgtttttat 550

 atggagtagc actcactgaa agaggaaaga aagaggatta tacagaagct 600

 gagaataaat ttctggtgat gaagatgatg atccaagaaa atgaaatttg 650

 tgaaaacttt atgtctttag tttattttgg acgtggttta ctgcgatgtg 700

 ctcaaaagag atataatgga ggactgctag aatttcataa aagcttacaa 750

 gaaattggag acaaaaatga ccattggttt gacatagatc ctacagaaga 800

 tgaagattta cctacaactt ttaaagatct tcttaataat tttatcaaga 850

 caactgaaag caatataatg aagcagacga tttgtagtta cctagattgt 900

 gaacgatctt gtgaagctga cattttgaag aacaccagtt ataagggatt 950

 ttttcagtta atgtgcagta aaagttgctg tgtttatttc cataaaattt 1000

 gctggaaaaa gttcaagaat ttaaagtatc caggtgaaaa tgatcagagt 1050

 tttagtggga aaaaatgttt gaaggaagga tgtacaggtg acatggtaag 1100

 gatgctgcaa tgtgatgtac ctggaattgt taaaattttg tttgaagttg 1150

 tgagaaagga tgaatatatc accattgaaa atttaggagc aagttataga 1200

 aagttgatat ctctgaaaat aactgatact gatataagac cgaagatcag 1250

 tttaaaattt aatacaaaag atgaaatgcc tatcttcaag cttgattata 1300

 attatttcta tcatctgctt catataatta ttatttctgg tactgacatt 1350

 gttcgacaaa tatttgatga ggctatgcca cctcctcttt tgaaaaaaga 1400

 gcttcttata cacaagaatg tgctggaatc ctactacaac catctttgga 1450

 ccaatcatcc tttgggtgga tcatggcatc tgctttatcc tcctaacaag 1500

 gagttaccgc aatccaaaca gtttgactta tgcctcctgt tagctcttat 1550

 aaaacattta aatgtgttcc ctgcacccaa aaaaggatgg aatatggaac 1600

 cgccatcttc tgacatctct aaatctgcag acatcctgag actgtgcaaa 1650

 tacagggata tcctccttag tgagattttg atgaatggtc tcactgagtc 1700

 acagttcaat tcaatttgga aaaaagtttc agatattctt ctgcgccttg 1750

 ggatgatgca agaggatatt gacaaagtga aggagaatcc cattgagaat 1800

 atctcccttg attaccatca gctatctgtc tacctaggca taccagtacc 1850

 agaaatcata cagaggatgt tatcctgcta tcaacaagga attgctctac 1900

 agtcaataac aggcagtcag cgtattgaaa tagaagagtt acagaatgag 1950

 gaagaagaac taagtccacc tctcatggag tacaatataa atgtgaaatc 2000

 acaccctgag atacagtttg cagaaattaa taaagatggg acctcaatac 2050

 ccagtgaatc ttcaacagaa tctcttaaag atctccagga agttaagagt 2100

 aaacaaagga aaaagaagaa gactaagaat aaaaagaata aagactcaaa 2150

 agaagaccaa gtcccatatg tggtagaaaa ggaagagcag ttgaggaaag 2200

 aacaagcaaa tccacactca gtcagtagac ttataaaaga tgatgcaagt 2250

 gatgttcaag aggattctgc aatggaagac aagttctata gcctggatga 2300

 attgcatatt ctggacatga tagagcaggg ctcagctggc aaagtaacta 2350

 cagactatgg agaaactgaa aaggaaaggc ttgctcgtca aaggcagctt 2400

 tataaattgc actatcagtg tgaagatttc aaaagacagt tgagaacagt 2450

 gacttttcgg tggcaagaaa accaaatgca gattaaaaag aaagacaaaa 2500

 ttatcgcatc tcttaatcaa caagttgctt ttggaatcaa taaggtttcc 2550

 aaattacagc gtcaaatcca tgctaaagat aatgaaatca agaaccttaa 2600

 agagcaactt tctatgaaaa gatctcagtg ggaaatggaa aaacataatc 2650

 tggaaagcac aatgaaaaca tacgtaagca aactgaacgc agaaactagc 2700

 agagctttaa cagccgaggt gtatttctta cagtgtcgta gggattttgg 2750

 tttgcttcat ctagagcaga ctgaaaagga atgtctcaat cagcttgcca 2800

 gggtgactca catggcagca agcaacctag aatcacttca attaaaggct 2850

 gcggtagaca gttggaatgc cattgtggca gatgttagaa acaagattgc 2900

 attcctcagg acacagtaca atgaacaaat aaacaaagtc aagcaaggat 2950

 ttgccttgag taccttgcct ccagtccagc ttcctcctcc accacccagt 3000

 cctgagatac tgatgcagca gttcttagga agaccccttg tgaaagaatc 3050

 tttctttaga cccatactta ctgttcctca aatgcctgca gtttgcccgg 3100

 gagtcgtctc tgcaactggc caacctagag cccccctgat gactggcata 3150

 gcctgggctc tgccagcgcc tgtgggagac gctgtgcctc ccagtgcagg 3200

 tctgcggagt gatccctcca tcatgaattg ggagagaatt acagacaggc 3250

 tgaaaactgc ctttccacag caaaccagaa aggaacttac agatttctta 3300

 cggaaattga aggatgctta tggaaaatcc ttgtctgaac tgacatttga 3350

 tgaaattgtt tgcaagattt cccagtttat tgaccccaaa aagtctcaga 3400

 gtcaaggaaa atcagtgtca aatgttaatt gtgtttcacc tagtcattct 3450

 ccatcacagc ctgatgctgc ccagccccca aaaccagcct ggaggccact 3500

 cacttcacag ggtcctgcca catgggaagg agccagtaat ccagatgagg 3550

 aagaggaaga agaagagcct tgtgtgatct gtcatgagaa tctgtctcca 3600

 gaaaatcttt cagttttgcc ttgcgctcac aaattccatg ctcagtgcat 3650

 tagaccatgg ttgatgcaac aggggacatg tccaacgtgc agactccacg 3700

 ttttgctacc agaagaattc cctggtcacc ccagccggca gttgcccaag 3750

 atctgataca aggtcggggt gtctatgcaa aggaagctca gttttctttt 3800

 attatgagct gcttgtttga gtggtgtaaa actatgtgct cttcaatata 3850

 gtgctaaaga agccagctaa ttttatcaaa gcagcagcca aagaagtcag 3900

 gacaaatctt caggacttgt gaaatgaact gaaagagctt gaagcagatg 3950

 gaattttaat agttacacta tatatgctct tagtaggttt ttttcttgta 4000

 gtggaaacat aactgttagc atatttctta ggatgttttt tcttgtcttt 4050

 ttaaattctt atttcactca tcctttactc tcccctcaag tattctacac 4100

 tttaatttcc tgaaataaat ttaaggaaaa gggaaatagt aaagaagtag 4150

 gaatgggtgc agcacaccag catggcacat gaatacacat gtaactaacc 4200

 tgcacattgt gcacatgtac cctaaaactt aaagtataat aataat 4246

<210> 1600
<211> 1208
<212> PRT
<213> Homo sapien

<400> 1600
 Met Asp Ser Leu Pro Asp Glu Phe Phe Val Arg His Pro Ala Val
   1               5                  10                  15

 Glu Asp Gln Arg Lys Glu Glu Thr Glu Asn Lys Leu Glu Lys Ser
                  20                  25                  30

 Ser Gly Gln Leu Asn Lys Gln Glu Asn Asp Ile Pro Thr Asp Leu
                  35                  40                  45

 Val Pro Val Asn Leu Leu Leu Glu Val Lys Lys Leu Leu Asn Ala
                  50                  55                  60

 Ile Asn Thr Leu Pro Lys Gly Val Val Pro His Ile Lys Lys Phe
                  65                  70                  75

 Leu Gln Glu Asp Phe Ser Phe Gln Thr Met Gln Arg Glu Val Ala
                  80                  85                  90

 Ala Asn Ser Gln Asn Gly Glu Glu Ile Val Pro Ala Leu Thr Leu
                  95                 100                 105

 Arg Phe Leu Ile Thr Gln Leu Glu Ala Ala Leu Arg Asn Ile Gln
                 110                 115                 120

 Ala Gly Asn Tyr Thr Ala His Gln Ile Asn Ile Gly Tyr Tyr Leu
                 125                 130                 135

 Thr Leu Leu Phe Leu Tyr Gly Val Ala Leu Thr Glu Arg Gly Lys
                 140                 145                 150

 Lys Glu Asp Tyr Thr Glu Ala Glu Asn Lys Phe Leu Val Met Lys
                 155                 160                 165

 Met Met Ile Gln Glu Asn Glu Ile Cys Glu Asn Phe Met Ser Leu
                 170                 175                 180

 Val Tyr Phe Gly Arg Gly Leu Leu Arg Cys Ala Gln Lys Arg Tyr
                 185                 190                 195

 Asn Gly Gly Leu Leu Glu Phe His Lys Ser Leu Gln Glu Ile Gly
                 200                 205                 210

 Asp Lys Asn Asp His Trp Phe Asp Ile Asp Pro Thr Glu Asp Glu
                 215                 220                 225

 Asp Leu Pro Thr Thr Phe Lys Asp Leu Leu Asn Asn Phe Ile Lys
                 230                 235                 240

 Thr Thr Glu Ser Asn Ile Met Lys Gln Thr Ile Cys Ser Tyr Leu
                 245                 250                 255

 Asp Cys Glu Arg Ser Cys Glu Ala Asp Ile Leu Lys Asn Thr Ser
                 260                 265                 270

 Tyr Lys Gly Phe Phe Gln Leu Met Cys Ser Lys Ser Cys Cys Val
                 275                 280                 285

 Tyr Phe His Lys Ile Cys Trp Lys Lys Phe Lys Asn Leu Lys Tyr
                 290                 295                 300

 Pro Gly Glu Asn Asp Gln Ser Phe Ser Gly Lys Lys Cys Leu Lys
                 305                 310                 315

 Glu Gly Cys Thr Gly Asp Met Val Arg Met Leu Gln Cys Asp Val
                 320                 325                 330

 Pro Gly Ile Val Lys Ile Leu Phe Glu Val Val Arg Lys Asp Glu
                 335                 340                 345

 Tyr Ile Thr Ile Glu Asn Leu Gly Ala Ser Tyr Arg Lys Leu Ile
                 350                 355                 360

 Ser Leu Lys Ile Thr Asp Thr Asp Ile Arg Pro Lys Ile Ser Leu
                 365                 370                 375

 Lys Phe Asn Thr Lys Asp Glu Met Pro Ile Phe Lys Leu Asp Tyr
                 380                 385                 390

 Asn Tyr Phe Tyr His Leu Leu His Ile Ile Ile Ile Ser Gly Thr
                 395                 400                 405

 Asp Ile Val Arg Gln Ile Phe Asp Glu Ala Met Pro Pro Pro Leu
                 410                 415                 420

 Leu Lys Lys Glu Leu Leu Ile His Lys Asn Val Leu Glu Ser Tyr
                 425                 430                 435

 Tyr Asn His Leu Trp Thr Asn His Pro Leu Gly Gly Ser Trp His
                 440                 445                 450

 Leu Leu Tyr Pro Pro Asn Lys Glu Leu Pro Gln Ser Lys Gln Phe
                 455                 460                 465

 Asp Leu Cys Leu Leu Leu Ala Leu Ile Lys His Leu Asn Val Phe
                 470                 475                 480

 Pro Ala Pro Lys Lys Gly Trp Asn Met Glu Pro Pro Ser Ser Asp
                 485                 490                 495

 Ile Ser Lys Ser Ala Asp Ile Leu Arg Leu Cys Lys Tyr Arg Asp
                 500                 505                 510

 Ile Leu Leu Ser Glu Ile Leu Met Asn Gly Leu Thr Glu Ser Gln
                 515                 520                 525

 Phe Asn Ser Ile Trp Lys Lys Val Ser Asp Ile Leu Leu Arg Leu
                 530                 535                 540

 Gly Met Met Gln Glu Asp Ile Asp Lys Val Lys Glu Asn Pro Ile
                 545                 550                 555

 Glu Asn Ile Ser Leu Asp Tyr His Gln Leu Ser Val Tyr Leu Gly
                 560                 565                 570

 Ile Pro Val Pro Glu Ile Ile Gln Arg Met Leu Ser Cys Tyr Gln
                 575                 580                 585

 Gln Gly Ile Ala Leu Gln Ser Ile Thr Gly Ser Gln Arg Ile Glu
                 590                 595                 600

 Ile Glu Glu Leu Gln Asn Glu Glu Glu Glu Leu Ser Pro Pro Leu
                 605                 610                 615

 Met Glu Tyr Asn Ile Asn Val Lys Ser His Pro Glu Ile Gln Phe
                 620                 625                 630

 Ala Glu Ile Asn Lys Asp Gly Thr Ser Ile Pro Ser Glu Ser Ser
                 635                 640                 645

 Thr Glu Ser Leu Lys Asp Leu Gln Glu Val Lys Ser Lys Gln Arg
                 650                 655                 660

 Lys Lys Lys Lys Thr Lys Asn Lys Lys Asn Lys Asp Ser Lys Glu
                 665                 670                 675

 Asp Gln Val Pro Tyr Val Val Glu Lys Glu Glu Gln Leu Arg Lys
                 680                 685                 690

 Glu Gln Ala Asn Pro His Ser Val Ser Arg Leu Ile Lys Asp Asp
                 695                 700                 705

 Ala Ser Asp Val Gln Glu Asp Ser Ala Met Glu Asp Lys Phe Tyr
                 710                 715                 720

 Ser Leu Asp Glu Leu His Ile Leu Asp Met Ile Glu Gln Gly Ser
                 725                 730                 735

 Ala Gly Lys Val Thr Thr Asp Tyr Gly Glu Thr Glu Lys Glu Arg
                 740                 745                 750

 Leu Ala Arg Gln Arg Gln Leu Tyr Lys Leu His Tyr Gln Cys Glu
                 755                 760                 765

 Asp Phe Lys Arg Gln Leu Arg Thr Val Thr Phe Arg Trp Gln Glu
                 770                 775                 780

 Asn Gln Met Gln Ile Lys Lys Lys Asp Lys Ile Ile Ala Ser Leu
                 785                 790                 795

 Asn Gln Gln Val Ala Phe Gly Ile Asn Lys Val Ser Lys Leu Gln
                 800                 805                 810

 Arg Gln Ile His Ala Lys Asp Asn Glu Ile Lys Asn Leu Lys Glu
                 815                 820                 825

 Gln Leu Ser Met Lys Arg Ser Gln Trp Glu Met Glu Lys His Asn
                 830                 835                 840

 Leu Glu Ser Thr Met Lys Thr Tyr Val Ser Lys Leu Asn Ala Glu
                 845                 850                 855

 Thr Ser Arg Ala Leu Thr Ala Glu Val Tyr Phe Leu Gln Cys Arg
                 860                 865                 870

 Arg Asp Phe Gly Leu Leu His Leu Glu Gln Thr Glu Lys Glu Cys
                 875                 880                 885

 Leu Asn Gln Leu Ala Arg Val Thr His Met Ala Ala Ser Asn Leu
                 890                 895                 900

 Glu Ser Leu Gln Leu Lys Ala Ala Val Asp Ser Trp Asn Ala Ile
                 905                 910                 915

 Val Ala Asp Val Arg Asn Lys Ile Ala Phe Leu Arg Thr Gln Tyr
                 920                 925                 930

 Asn Glu Gln Ile Asn Lys Val Lys Gln Gly Phe Ala Leu Ser Thr
                 935                 940                 945

 Leu Pro Pro Val Gln Leu Pro Pro Pro Pro Pro Ser Pro Glu Ile
                 950                 955                 960

 Leu Met Gln Gln Phe Leu Gly Arg Pro Leu Val Lys Glu Ser Phe
                 965                 970                 975

 Phe Arg Pro Ile Leu Thr Val Pro Gln Met Pro Ala Val Cys Pro
                 980                 985                 990

 Gly Val Val Ser Ala Thr Gly Gln Pro Arg Ala Pro Leu Met Thr
                 995                1000                1005

 Gly Ile Ala Trp Ala Leu Pro Ala Pro Val Gly Asp Ala Val Pro
                1010                1015                1020

 Pro Ser Ala Gly Leu Arg Ser Asp Pro Ser Ile Met Asn Trp Glu
                1025                1030                1035

 Arg Ile Thr Asp Arg Leu Lys Thr Ala Phe Pro Gln Gln Thr Arg
                1040                1045                1050

 Lys Glu Leu Thr Asp Phe Leu Arg Lys Leu Lys Asp Ala Tyr Gly
                1055                1060                1065

 Lys Ser Leu Ser Glu Leu Thr Phe Asp Glu Ile Val Cys Lys Ile
                1070                1075                1080

 Ser Gln Phe Ile Asp Pro Lys Lys Ser Gln Ser Gln Gly Lys Ser
                1085                1090                1095

 Val Ser Asn Val Asn Cys Val Ser Pro Ser His Ser Pro Ser Gln
                1100                1105                1110

 Pro Asp Ala Ala Gln Pro Pro Lys Pro Ala Trp Arg Pro Leu Thr
                1115                1120                1125

 Ser Gln Gly Pro Ala Thr Trp Glu Gly Ala Ser Asn Pro Asp Glu
                1130                1135                1140

 Glu Glu Glu Glu Glu Glu Pro Cys Val Ile Cys His Glu Asn Leu
                1145                1150                1155

 Ser Pro Glu Asn Leu Ser Val Leu Pro Cys Ala His Lys Phe His
                1160                1165                1170

 Ala Gln Cys Ile Arg Pro Trp Leu Met Gln Gln Gly Thr Cys Pro
                1175                1180                1185

 Thr Cys Arg Leu His Val Leu Leu Pro Glu Glu Phe Pro Gly His
                1190                1195                1200

 Pro Ser Arg Gln Leu Pro Lys Ile
                1205

<210> 1601
<211> 1548
<212> DNA
<213> Homo sapien

<400> 1601
 agacttggaa accccaaagt gtccgcgacc ctgcacggca gctcccttcc 50

 agcttcatgg gcaaagtgtg gaaacagcag atgtaccctc agtacgccac 100

 ctactattac ccccagtatc tgcaagccaa gcagtctctg gtcccagccc 150

 accccatggc ccctcccagt cccagcacca ccagcagtaa taacaacagt 200

 agcagcagta gcaactcagg atgggatcag ctcagcaaaa cgaacctcta 250

 tatccgagga ctgcctcccc acaccaccga ccaggacctg gtgaagctct 300

 gtcaaccata tgggaaaata gtctccacaa aggcaatttt ggataagaca 350

 acgaacaaat gcaaaggtta tggttttgtc gactttgaca gccctgcagc 400

 agctcaaaaa gctgtgtctg ccctgaaggc cagtggggtt caagctcaaa 450

 tggcaaagca acaggaacaa gatcctacca acctctacat ttctaatttg 500

 ccactctcca tggatgagca agaactagaa aatatgctca aaccatttgg 550

 acaagttatt tctacaagga tactacgtga ttccagtggt acaagtcgtg 600

 gtgttggctt tgctaggatg gaatcaacag aaaaatgtga agctgttatt 650

 ggtcatttta atggaaaatt tattaagaca ccaccaggag tttctgcccc 700

 cacagaacct ttattgtgta agtttgctga tggaggacag aaaaagagac 750

 agaacccaaa caaatacatc cctaatggaa gaccatggca tagagaagga 800

 gaggctggaa tgacacttac ttacgaccca actacagctg ctatacagaa 850

 cggattttat ccttcaccat acagtattgc tacaaaccga atgatcactc 900

 aaacttctat tacaccctat attgcatctc ctgtatctgc ctaccaggtg 950

 gcaaaggaaa ccagagaaaa caagtatcgg ggctctgcta tcaaggtgca 1000

 aagtccttcg tggatgcaac ctcaaccata tattctacag caccctggtg 1050

 ccgtgttaac tccctcaatg gagcacacca tgtcactaca gcccgcatca 1100

 atgatcagcc ctctggccca gcagatgagt catctgtcac taggcagcac 1150

 cggaacatac atgcctgcaa cgtcagctat gcaaggagcc tacttgccac 1200

 agtatgcaca tatgcagacg acagcggttc ctgttgagga ggcaagtggt 1250

 caacagcagg tggctgtcga gacgtctaat gaccattctc catatacctt 1300

 tcaacctaat aagtaactgt gagatgtaca gaaaggtgtt cttacatgaa 1350

 gaagggtgtg aaggctgaac aatcatggat ttttctgatc aattgtgctt 1400

 taggaaatta ttgacagttt tgcacaggtt cttgaaaacg ttatttataa 1450

 tgaaatcaac taaaactatt tttgctataa gttctataag gtgcataaaa 1500

 cccttaaatt catctagtag ctgttccccc gaacaggttt attttagt 1548

<210> 1602
<211> 419
<212> PRT
<213> Homo sapien

<400> 1602
 Met Gly Lys Val Trp Lys Gln Gln Met Tyr Pro Gln Tyr Ala Thr
   1               5                  10                  15

 Tyr Tyr Tyr Pro Gln Tyr Leu Gln Ala Lys Gln Ser Leu Val Pro
                  20                  25                  30

 Ala His Pro Met Ala Pro Pro Ser Pro Ser Thr Thr Ser Ser Asn
                  35                  40                  45

 Asn Asn Ser Ser Ser Ser Ser Asn Ser Gly Trp Asp Gln Leu Ser
                  50                  55                  60

 Lys Thr Asn Leu Tyr Ile Arg Gly Leu Pro Pro His Thr Thr Asp
                  65                  70                  75

 Gln Asp Leu Val Lys Leu Cys Gln Pro Tyr Gly Lys Ile Val Ser
                  80                  85                  90

 Thr Lys Ala Ile Leu Asp Lys Thr Thr Asn Lys Cys Lys Gly Tyr
                  95                 100                 105

 Gly Phe Val Asp Phe Asp Ser Pro Ala Ala Ala Gln Lys Ala Val
                 110                 115                 120

 Ser Ala Leu Lys Ala Ser Gly Val Gln Ala Gln Met Ala Lys Gln
                 125                 130                 135

 Gln Glu Gln Asp Pro Thr Asn Leu Tyr Ile Ser Asn Leu Pro Leu
                 140                 145                 150

 Ser Met Asp Glu Gln Glu Leu Glu Asn Met Leu Lys Pro Phe Gly
                 155                 160                 165

 Gln Val Ile Ser Thr Arg Ile Leu Arg Asp Ser Ser Gly Thr Ser
                 170                 175                 180

 Arg Gly Val Gly Phe Ala Arg Met Glu Ser Thr Glu Lys Cys Glu
                 185                 190                 195

 Ala Val Ile Gly His Phe Asn Gly Lys Phe Ile Lys Thr Pro Pro
                 200                 205                 210

 Gly Val Ser Ala Pro Thr Glu Pro Leu Leu Cys Lys Phe Ala Asp
                 215                 220                 225

 Gly Gly Gln Lys Lys Arg Gln Asn Pro Asn Lys Tyr Ile Pro Asn
                 230                 235                 240

 Gly Arg Pro Trp His Arg Glu Gly Glu Ala Gly Met Thr Leu Thr
                 245                 250                 255

 Tyr Asp Pro Thr Thr Ala Ala Ile Gln Asn Gly Phe Tyr Pro Ser
                 260                 265                 270

 Pro Tyr Ser Ile Ala Thr Asn Arg Met Ile Thr Gln Thr Ser Ile
                 275                 280                 285

 Thr Pro Tyr Ile Ala Ser Pro Val Ser Ala Tyr Gln Val Ala Lys
                 290                 295                 300

 Glu Thr Arg Glu Asn Lys Tyr Arg Gly Ser Ala Ile Lys Val Gln
                 305                 310                 315

 Ser Pro Ser Trp Met Gln Pro Gln Pro Tyr Ile Leu Gln His Pro
                 320                 325                 330

 Gly Ala Val Leu Thr Pro Ser Met Glu His Thr Met Ser Leu Gln
                 335                 340                 345

 Pro Ala Ser Met Ile Ser Pro Leu Ala Gln Gln Met Ser His Leu
                 350                 355                 360

 Ser Leu Gly Ser Thr Gly Thr Tyr Met Pro Ala Thr Ser Ala Met
                 365                 370                 375

 Gln Gly Ala Tyr Leu Pro Gln Tyr Ala His Met Gln Thr Thr Ala
                 380                 385                 390

 Val Pro Val Glu Glu Ala Ser Gly Gln Gln Gln Val Ala Val Glu
                 395                 400                 405

 Thr Ser Asn Asp His Ser Pro Tyr Thr Phe Gln Pro Asn Lys
                 410                 415

<210> 1603
<211> 1855
<212> DNA
<213> Homo sapien

<400> 1603
 ccatgtcgct cactgtcgtc agcatggcgt gcgttgggtt cttcttgctg 50

 cagggggcct ggccactcat gggtggtcag gacaaaccct tcctgtctgc 100

 ccggcccagc actgtggtgc ctcgaggagg acacgtggct cttcagtgtc 150

 actatcgtcg tgggtttaac aatttcatgc tgtacaaaga agacagaagc 200

 cacgttccca tcttccacgg cagaatattc caggagagct tcatcatggg 250

 ccctgtgacc ccagcacatg cagggaccta cagatgtcgg ggttcacgcc 300

 cacactccct cactgggtgg tcggcaccca gcaaccccct ggtgatcatg 350

 gtcacaggaa accacagaaa accttccctc ctggcccacc cagggcccct 400

 gctgaaatca ggagagacag tcatcctgca atgttggtca gatgtcatgt 450

 ttgagcactt ctttctgcac agagatggga tctctgagga cccctcacgc 500

 ctcgttggac agatccatga tggggtctcc aaggccaact tctccatcgg 550

 tcccttgatg cctgtccttg caggaaccta cagatgttat ggttctgttc 600

 ctcactcccc ctatcagttg tcagctccca gtgaccccct ggacatcgtg 650

 atcacaggtc tatatgagaa accttctctc tcagcccagc cgggccccac 700

 ggttcaggca ggagagaacg tgaccttgtc ctgtagctcc tggagctcct 750

 atgacatcta ccatctgtcc agggaagggg aggcccatga acgtaggctc 800

 cgtgcagtgc ccaaggtcaa cagaacattc caggcagact ttcctctggg 850

 ccctgccacc cacggaggga cctacagatg cttcggctct ttccgtgccc 900

 tgccctgcgt gtggtcaaac tcaagtgacc cactgcttgt ttctgtcaca 950

 ggaaaccctt caagtagttg gccttcaccc acagaaccaa gctccaaatc 1000

 tggtatctgc agacacctgc atgttctgat tgggacctca gtggtcatct 1050

 tcctcttcat cctcctcctc ttctttctcc tttatcgctg gtgctccaac 1100

 aaaaagaatg ctgctgtaat ggaccaagag cctgcggggg acagaacagt 1150

 gaataggcag gactctgatg aacaagaccc tcaggaggtg acgtacgcac 1200

 agttggatca ctgcgttttc atacagagaa aaatcagtcg cccttctcag 1250

 aggcccaaga cacccctaac agataccagc gtgtacacgg aacttccaaa 1300

 tgctgagccc agatccaaag ttgtctcctg cccacgagca ccacagtcag 1350

 gtcttgaggg ggttttctag ggagacaaca gccctgtctc aaaaccaggt 1400

 tgccagatcc aatgaaccag cagctggaat ctgaaggcat cagtctgcat 1450

 cttaggggat cgctcttcct cacaccacga atctgaacat gcctctctct 1500

 tgcttacaaa tgcctaaggt cgccactgcc tgctgcagag aaaacacact 1550

 cctttgctta gcccacaagg tatctatttc acttgacccc tgcccacctc 1600

 tccaacctaa ctggcttact tcctagtcct acttgaggct gcaatcacac 1650

 tgaggaactc acaattccaa acatacaaga ggctccctct taacacggca 1700

 cttacacact tgctgttcca ccttccctca tgctgttcca cctcccctca 1750

 gactatcttt cagccttctg tcatcagtaa aatttataaa ttttttttat 1800

 aacttcagtg tagctctctc ctcttcaaat aaacatgtct gccctcatgg 1850

 tttcg 1855

<210> 1604
<211> 455
<212> PRT
<213> Homo sapien

<400> 1604
 Met Ser Leu Thr Val Val Ser Met Ala Cys Val Gly Phe Phe Leu
   1               5                  10                  15

 Leu Gln Gly Ala Trp Pro Leu Met Gly Gly Gln Asp Lys Pro Phe
                  20                  25                  30

 Leu Ser Ala Arg Pro Ser Thr Val Val Pro Arg Gly Gly His Val
                  35                  40                  45

 Ala Leu Gln Cys His Tyr Arg Arg Gly Phe Asn Asn Phe Met Leu
                  50                  55                  60

 Tyr Lys Glu Asp Arg Ser His Val Pro Ile Phe His Gly Arg Ile
                  65                  70                  75

 Phe Gln Glu Ser Phe Ile Met Gly Pro Val Thr Pro Ala His Ala
                  80                  85                  90

 Gly Thr Tyr Arg Cys Arg Gly Ser Arg Pro His Ser Leu Thr Gly
                  95                 100                 105

 Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Met Val Thr Gly Asn
                 110                 115                 120

 His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu Leu Lys
                 125                 130                 135

 Ser Gly Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Met Phe
                 140                 145                 150

 Glu His Phe Phe Leu His Arg Asp Gly Ile Ser Glu Asp Pro Ser
                 155                 160                 165

 Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe
                 170                 175                 180

 Ser Ile Gly Pro Leu Met Pro Val Leu Ala Gly Thr Tyr Arg Cys
                 185                 190                 195

 Tyr Gly Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser
                 200                 205                 210

 Asp Pro Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser
                 215                 220                 225

 Leu Ser Ala Gln Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val
                 230                 235                 240

 Thr Leu Ser Cys Ser Ser Trp Ser Ser Tyr Asp Ile Tyr His Leu
                 245                 250                 255

 Ser Arg Glu Gly Glu Ala His Glu Arg Arg Leu Arg Ala Val Pro
                 260                 265                 270

 Lys Val Asn Arg Thr Phe Gln Ala Asp Phe Pro Leu Gly Pro Ala
                 275                 280                 285

 Thr His Gly Gly Thr Tyr Arg Cys Phe Gly Ser Phe Arg Ala Leu
                 290                 295                 300

 Pro Cys Val Trp Ser Asn Ser Ser Asp Pro Leu Leu Val Ser Val
                 305                 310                 315

 Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser Pro Thr Glu Pro Ser
                 320                 325                 330

 Ser Lys Ser Gly Ile Cys Arg His Leu His Val Leu Ile Gly Thr
                 335                 340                 345

 Ser Val Val Ile Phe Leu Phe Ile Leu Leu Leu Phe Phe Leu Leu
                 350                 355                 360

 Tyr Arg Trp Cys Ser Asn Lys Lys Asn Ala Ala Val Met Asp Gln
                 365                 370                 375

 Glu Pro Ala Gly Asp Arg Thr Val Asn Arg Gln Asp Ser Asp Glu
                 380                 385                 390

 Gln Asp Pro Gln Glu Val Thr Tyr Ala Gln Leu Asp His Cys Val
                 395                 400                 405

 Phe Ile Gln Arg Lys Ile Ser Arg Pro Ser Gln Arg Pro Lys Thr
                 410                 415                 420

 Pro Leu Thr Asp Thr Ser Val Tyr Thr Glu Leu Pro Asn Ala Glu
                 425                 430                 435

 Pro Arg Ser Lys Val Val Ser Cys Pro Arg Ala Pro Gln Ser Gly
                 440                 445                 450

 Leu Glu Gly Val Phe
                 455

<210> 1605
<211> 1855
<212> DNA
<213> Homo sapien

<400> 1605
 ccatgtcgct cactgtcgtc agcatggcgt gcgttgggtt cttcttgctg 50

 cagggggcct ggccactcat gggtggtcag gacaaaccct tcctgtctgc 100

 ccggcccagc actgtggtgc ctcgaggagg acacgtggct cttcagtgtc 150

 actatcgtcg tgggtttaac aatttcatgc tgtacaaaga agacagaagc 200

 cacgttccca tcttccacgg cagaatattc caggagagct tcatcatggg 250

 ccctgtgacc ccagcacatg cagggaccta cagatgtcgg ggttcacgcc 300

 cacactccct cactgggtgg tcggcaccca gcaaccccct ggtgatcatg 350

 gtcacaggaa accacagaaa accttccctc ctggcccacc cagggcccct 400

 gctgaaatca ggagagacag tcatcctgca atgttggtca gatgtcatgt 450

 ttgagcactt ctttctgcac agagatggga tctctgagga cccctcacgc 500

 ctcgttggac agatccatga tggggtctcc aaggccaact tctccatcgg 550

 tcccttgatg cctgtccttg caggaaccta cagatgttat ggttctgttc 600

 ctcactcccc ctatcagttg tcagctccca gtgaccccct ggacatcgtg 650

 atcacaggtc tatatgagaa accttctctc tcagcccagc cgggccccac 700

 ggttcaggca ggagagaacg tgaccttgtc ctgtagctcc tggagctcct 750

 atgacatcta ccatctgtcc agggaagggg aggcccatga acgtaggctc 800

 cgtgcagtgc ccaaggtcaa cagaacattc caggcagact ttcctctggg 850

 ccctgccacc cacggaggga cctacagatg cttcggctct ttccgtgccc 900

 tgccctgcgt gtggtcaaac tcaagtgacc cactgcttgt ttctgtcaca 950

 ggaaaccctt caagtagttg gccttcaccc acagaaccaa gctccaaatc 1000

 tggtatctgc agacacctgc atgttctgat tgggacctca gtggtcatct 1050

 tcctcttcat cctcctcctc ttctttctcc tttatcgctg gtgctccaac 1100

 aaaaagaatg ctgctgtaat ggaccaagag cctgcggggg acagaacagt 1150

 gaataggcag gactctgatg aacaagaccc tcaggaggtg acgtacgcac 1200

 agttggatca ctgcgttttc atacagagaa aaatcagtcg cccttctcag 1250

 aggcccaaga cacccctaac agataccagc gtgtacacgg aacttccaaa 1300

 tgctgagccc agatccaaag ttgtctcctg cccacgagca ccacagtcag 1350

 gtcttgaggg ggttttctag ggagacaaca gccctgtctc aaaaccaggt 1400

 tgccagatcc aatgaaccag cagctggaat ctgaaggcat cagtctgcat 1450

 cttaggggat cgctcttcct cacaccacga atctgaacat gcctctctct 1500

 tgcttacaaa tgcctaaggt cgccactgcc tgctgcagag aaaacacact 1550

 cctttgctta gcccacaagg tatctatttc acttgacccc tgcccacctc 1600

 tccaacctaa ctggcttact tcctagtcct acttgaggct gcaatcacac 1650

 tgaggaactc acaattccaa acatacaaga ggctccctct taacacggca 1700

 cttacacact tgctgttcca ccttccctca tgctgttcca cctcccctca 1750

 gactatcttt cagccttctg tcatcagtaa aatttataaa ttttttttat 1800

 aacttcagtg tagctctctc ctcttcaaat aaacatgtct gccctcatgg 1850

 tttcg 1855

<210> 1606
<211> 455
<212> PRT
<213> Homo sapien

<400> 1606
 Met Ser Leu Thr Val Val Ser Met Ala Cys Val Gly Phe Phe Leu
   1               5                  10                  15

 Leu Gln Gly Ala Trp Pro Leu Met Gly Gly Gln Asp Lys Pro Phe
                  20                  25                  30

 Leu Ser Ala Arg Pro Ser Thr Val Val Pro Arg Gly Gly His Val
                  35                  40                  45

 Ala Leu Gln Cys His Tyr Arg Arg Gly Phe Asn Asn Phe Met Leu
                  50                  55                  60

 Tyr Lys Glu Asp Arg Ser His Val Pro Ile Phe His Gly Arg Ile
                  65                  70                  75

 Phe Gln Glu Ser Phe Ile Met Gly Pro Val Thr Pro Ala His Ala
                  80                  85                  90

 Gly Thr Tyr Arg Cys Arg Gly Ser Arg Pro His Ser Leu Thr Gly
                  95                 100                 105

 Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Met Val Thr Gly Asn
                 110                 115                 120

 His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu Leu Lys
                 125                 130                 135

 Ser Gly Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Met Phe
                 140                 145                 150

 Glu His Phe Phe Leu His Arg Asp Gly Ile Ser Glu Asp Pro Ser
                 155                 160                 165

 Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe
                 170                 175                 180

 Ser Ile Gly Pro Leu Met Pro Val Leu Ala Gly Thr Tyr Arg Cys
                 185                 190                 195

 Tyr Gly Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser
                 200                 205                 210

 Asp Pro Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser
                 215                 220                 225

 Leu Ser Ala Gln Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val
                 230                 235                 240

 Thr Leu Ser Cys Ser Ser Trp Ser Ser Tyr Asp Ile Tyr His Leu
                 245                 250                 255

 Ser Arg Glu Gly Glu Ala His Glu Arg Arg Leu Arg Ala Val Pro
                 260                 265                 270

 Lys Val Asn Arg Thr Phe Gln Ala Asp Phe Pro Leu Gly Pro Ala
                 275                 280                 285

 Thr His Gly Gly Thr Tyr Arg Cys Phe Gly Ser Phe Arg Ala Leu
                 290                 295                 300

 Pro Cys Val Trp Ser Asn Ser Ser Asp Pro Leu Leu Val Ser Val
                 305                 310                 315

 Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser Pro Thr Glu Pro Ser
                 320                 325                 330

 Ser Lys Ser Gly Ile Cys Arg His Leu His Val Leu Ile Gly Thr
                 335                 340                 345

 Ser Val Val Ile Phe Leu Phe Ile Leu Leu Leu Phe Phe Leu Leu
                 350                 355                 360

 Tyr Arg Trp Cys Ser Asn Lys Lys Asn Ala Ala Val Met Asp Gln
                 365                 370                 375

 Glu Pro Ala Gly Asp Arg Thr Val Asn Arg Gln Asp Ser Asp Glu
                 380                 385                 390

 Gln Asp Pro Gln Glu Val Thr Tyr Ala Gln Leu Asp His Cys Val
                 395                 400                 405

 Phe Ile Gln Arg Lys Ile Ser Arg Pro Ser Gln Arg Pro Lys Thr
                 410                 415                 420

 Pro Leu Thr Asp Thr Ser Val Tyr Thr Glu Leu Pro Asn Ala Glu
                 425                 430                 435

 Pro Arg Ser Lys Val Val Ser Cys Pro Arg Ala Pro Gln Ser Gly
                 440                 445                 450

 Leu Glu Gly Val Phe
                 455

<210> 1607
<211> 2603
<212> DNA
<213> Homo sapien

<400> 1607
 ccacgcgtcc gcgctcccct cagctcctgc agtgctaatt aagggaggga 50

 gcagcgggga gcttgcagtg accaagaggg tgttgaggct aggaggccac 100

 gataaacagg atacgataaa agtccttaac caagacgcag atgggaagaa 150

 gcgttagagc gagcagcact cacatctcaa gaaccagcct ttcaaacagt 200

 ttccagagat ggattatcct actttacttt tggctcttct tcatgtatac 250

 agagctctat gtgaagaggt gctttggcat acatcagttc cctttgccga 300

 gaacatgtct ctagaatgtg tgtatccatc aatgggcatc ttaacacagg 350

 tggagtggtt caagatcggg acccagcagg attccatagc cattttcagc 400

 cctactcatg gcatggtcat aaggaagccc tatgctgaga gggtttactt 450

 tttgaattca acgatggctt ccaataacat gactcttttc tttcggaatg 500

 cctctgaaga tgatgttggc tactattcct gctctcttta cacttaccca 550

 cagggaactt ggcagaaggt gatacaggtg gttcagtcag atagttttga 600

 ggcagctgtg ccatcaaata gccacattgt ttcggaacct ggaaagaatg 650

 tcacactcac ttgtcagcct cagatgacgt ggcctgtgca ggcagtgagg 700

 tgggaaaaga tccagccccg tcagatcgac ctcttaactt actgcaactt 750

 ggtccatggc agaaatttca cctccaagtt cccaagacaa atagtgagca 800

 actgcagcca cggaaggtgg agcgtcatcg tcatccccga tgtcacagtc 850

 tcagactcgg ggctttaccg ctgctacttg caggccagcg caggagaaaa 900

 cgaaaccttc gtgatgagat tgactgtagc cgagggtaaa accgataacc 950

 aatataccct ctttgtggct ggagggacag ttttattgtt gttgtttgtt 1000

 atctcaatta ccaccatcat tgtcattttc cttaacagaa ggagaaggag 1050

 agagagaaga gatctattta cagagtcctg ggatacacag aaggcaccca 1100

 ataactatag aagtcccatc tctaccggtc aacctaccaa tcaatccatg 1150

 gatgatacaa gagaggatat ttatgtcaac tatccaacct tctctcgcag 1200

 accaaagact agagtttaag cttattcttg acatgagtgc attagtaatg 1250

 actcttatgt actcatgcat ggatctttat gcaatttttt tccactaccc 1300

 aaggtctacc ttagatacta gttgtctgaa ttgagttact ttgataggaa 1350

 aaatacttca ttacctaaaa tcatttttca tagaactgtt tcagaaaacc 1400

 tgactctaac tggtttatat acaaaagaaa acttactgta tcatataaca 1450

 gaatgatcca ggggagatta agctttgggc aagggctatt taccagggct 1500

 taaatgttgt gtctagaatt aagtatgggc ataaactggc ttctgaatcc 1550

 ctttccagag tgttggatcc atttccctgg tcttggcctc actctcatgc 1600

 aggctttcct cttgtgttgg caagatggct gccaactctt ggcaattcat 1650

 acatccttgt ttctgtctgg tagagagttt gcttctcaaa tggagcaaac 1700

 aaatttgatt attttttcat tgttaaatag gcaacatgac cagaaaggat 1750

 ggaatggctt aagtaaacta agggttcact tctagagctg agaagcaggg 1800

 tcaaagcaca atactgggca attcagagca tggttagaag aggaaagggg 1850

 agtctcaaag ctggagagtt taccaacaaa tattgactgc agtgattaac 1900

 caagacattt ttgttaacta aaaagtgaaa tatgggatgg attctagaaa 1950

 tggggtatct ctgtccatac ttctagaatc cactctatca gcatagtcca 2000

 gaagaatacc tggcagtaga agaaatgaat attcaagagg aagataaatg 2050

 cgagagggca atcctttact attctcatat ttatttatct ctcattctgt 2100

 atagaattct tgccgccatc ccaggtctag ccttaggagc aaatgtagta 2150

 gatagtcgaa taataaataa cttaatgttt tggacatatt ttgtctactt 2200

 ttgagaatta tttttaatat gtaaattctc tcaaaagggt caggcaccta 2250

 gttattattt tttaatgatt atgtgaaagt tgaatataat ataccactaa 2300

 aagtgacagt tgaaagtggt ggcataggat ggtagggtag aaatttggga 2350

 gggaaaaaag aaattgggag ggtacaggca acaggagaaa ggaatcaaac 2400

 cacagaaaaa tacaaaggga aacttctgct tcactattca gacaaagaca 2450

 gccctaatga catcaccaac agtcaaagca attagagacc atacctaata 2500

 ttgtttaaat tctagatgta ggctaacaat gaaaagtatt tgccaaactg 2550

 aataaaactg tcatggttac cttgaaaaaa aaaaaaaaaa aaaaaaaaaa 2600

 aaa 2603

<210> 1608
<211> 336
<212> PRT
<213> Homo sapien

<400> 1608
 Met Asp Tyr Pro Thr Leu Leu Leu Ala Leu Leu His Val Tyr Arg
   1               5                  10                  15

 Ala Leu Cys Glu Glu Val Leu Trp His Thr Ser Val Pro Phe Ala
                  20                  25                  30

 Glu Asn Met Ser Leu Glu Cys Val Tyr Pro Ser Met Gly Ile Leu
                  35                  40                  45

 Thr Gln Val Glu Trp Phe Lys Ile Gly Thr Gln Gln Asp Ser Ile
                  50                  55                  60

 Ala Ile Phe Ser Pro Thr His Gly Met Val Ile Arg Lys Pro Tyr
                  65                  70                  75

 Ala Glu Arg Val Tyr Phe Leu Asn Ser Thr Met Ala Ser Asn Asn
                  80                  85                  90

 Met Thr Leu Phe Phe Arg Asn Ala Ser Glu Asp Asp Val Gly Tyr
                  95                 100                 105

 Tyr Ser Cys Ser Leu Tyr Thr Tyr Pro Gln Gly Thr Trp Gln Lys
                 110                 115                 120

 Val Ile Gln Val Val Gln Ser Asp Ser Phe Glu Ala Ala Val Pro
                 125                 130                 135

 Ser Asn Ser His Ile Val Ser Glu Pro Gly Lys Asn Val Thr Leu
                 140                 145                 150

 Thr Cys Gln Pro Gln Met Thr Trp Pro Val Gln Ala Val Arg Trp
                 155                 160                 165

 Glu Lys Ile Gln Pro Arg Gln Ile Asp Leu Leu Thr Tyr Cys Asn
                 170                 175                 180

 Leu Val His Gly Arg Asn Phe Thr Ser Lys Phe Pro Arg Gln Ile
                 185                 190                 195

 Val Ser Asn Cys Ser His Gly Arg Trp Ser Val Ile Val Ile Pro
                 200                 205                 210

 Asp Val Thr Val Ser Asp Ser Gly Leu Tyr Arg Cys Tyr Leu Gln
                 215                 220                 225

 Ala Ser Ala Gly Glu Asn Glu Thr Phe Val Met Arg Leu Thr Val
                 230                 235                 240

 Ala Glu Gly Lys Thr Asp Asn Gln Tyr Thr Leu Phe Val Ala Gly
                 245                 250                 255

 Gly Thr Val Leu Leu Leu Leu Phe Val Ile Ser Ile Thr Thr Ile
                 260                 265                 270

 Ile Val Ile Phe Leu Asn Arg Arg Arg Arg Arg Glu Arg Arg Asp
                 275                 280                 285

 Leu Phe Thr Glu Ser Trp Asp Thr Gln Lys Ala Pro Asn Asn Tyr
                 290                 295                 300

 Arg Ser Pro Ile Ser Thr Gly Gln Pro Thr Asn Gln Ser Met Asp
                 305                 310                 315

 Asp Thr Arg Glu Asp Ile Tyr Val Asn Tyr Pro Thr Phe Ser Arg
                 320                 325                 330

 Arg Pro Lys Thr Arg Val
                 335

<210> 1609
<211> 5010
<212> DNA
<213> Homo sapien

<400> 1609
 ggcggctcgg gacggaggac gcgctagtgt gagtgcgggc ttctagaact 50

 acaccgaccc tcgtgtcctc ccttcatcct gcggggctgg ctggagcggc 100

 cgctccggtg ctgtccagca gccataggga gccgcacggg gagcgggaaa 150

 gcggtcgcgg ccccaggcgg ggcggccggg atggagcggg gccgcgagcc 200

 tgtggggaag gggctgtggc ggcgcctcga gcggctgcag gttcttctgt 250

 gtggcagttc agaatgatgg atcaagctag atcagcattc tctaacttgt 300

 ttggtggaga accattgtca tatacccggt tcagcctggc tcggcaagta 350

 gatggcgata acagtcatgt ggagatgaaa cttgctgtag atgaagaaga 400

 aaatgctgac aataacacaa aggccaatgt cacaaaacca aaaaggtgta 450

 gtggaagtat ctgctatggg actattgctg tgatcgtctt tttcttgatt 500

 ggatttatga ttggctactt gggctattgt aaaggggtag aaccaaaaac 550

 tgagtgtgag agactggcag gaaccgagtc tccagtgagg gaggagccag 600

 gagaggactt ccctgcagca cgtcgcttat attgggatga cctgaagaga 650

 aagttgtcgg agaaactgga cagcacagac ttcaccagca ccatcaagct 700

 gctgaatgaa aattcatatg tccctcgtga ggctggatct caaaaagatg 750

 aaaatcttgc gttgtatgtt gaaaatcaat ttcgtgaatt taaactcagc 800

 aaagtctggc gtgatcaaca ttttgttaag attcaggtca aagacagcgc 850

 tcaaaactcg gtgatcatag ttgataagaa cggtagactt gtttacctgg 900

 tggagaatcc tgggggttat gtggcgtata gtaaggctgc aacagttact 950

 ggtaaactgg tccatgctaa ttttggtact aaaaaagatt ttgaggattt 1000

 atacactcct gtgaatggat ctatagtgat tgtcagagca gggaaaatca 1050

 cctttgcaga aaaggttgca aatgctgaaa gcttaaatgc aattggtgtg 1100

 ttgatataca tggaccagac taaatttccc attgttaacg cagaactttc 1150

 attctttgga catgctcatc tggggacagg tgacccttac acacctggat 1200

 tcccttcctt caatcacact cagtttccac catctcggtc atcaggattg 1250

 cctaatatac ctgtccagac aatctccaga gctgctgcag aaaagctgtt 1300

 tgggaatatg gaaggagact gtccctctga ctggaaaaca gactctacat 1350

 gtaggatggt aacctcagaa agcaagaatg tgaagctcac tgtgagcaat 1400

 gtgctgaaag agataaaaat tcttaacatc tttggagtta ttaaaggctt 1450

 tgtagaacca gatcactatg ttgtagttgg ggcccagaga gatgcatggg 1500

 gccctggagc tgcaaaatcc ggtgtaggca cagctctcct attgaaactt 1550

 gcccagatgt tctcagatat ggtcttaaaa gatgggtttc agcccagcag 1600

 aagcattatc tttgccagtt ggagtgctgg agactttgga tcggttggtg 1650

 ccactgaatg gctagaggga tacctttcgt ccctgcattt aaaggctttc 1700

 acttatatta atctggataa agcggttctt ggtaccagca acttcaaggt 1750

 ttctgccagc ccactgttgt atacgcttat tgagaaaaca atgcaaaatg 1800

 tgaagcatcc ggttactggg caatttctat atcaggacag caactgggcc 1850

 agcaaagttg agaaactcac tttagacaat gctgctttcc ctttccttgc 1900

 atattctgga atcccagcag tttctttctg tttttgcgag gacacagatt 1950

 atccttattt gggtaccacc atggacacct ataaggaact gattgagagg 2000

 attcctgagt tgaacaaagt ggcacgagca gctgcagagg tcgctggtca 2050

 gttcgtgatt aaactaaccc atgatgttga attgaacctg gactatgaga 2100

 ggtacaacag ccaactgctt tcatttgtga gggatctgaa ccaatacaga 2150

 gcagacataa aggaaatggg cctgagttta cagtggctgt attctgctcg 2200

 tggagacttc ttccgtgcta cttccagact aacaacagat ttcgggaatg 2250

 ctgagaaaac agacagattt gtcatgaaga aactcaatga tcgtgtcatg 2300

 agagtggagt atcacttcct ctctccctac gtatctccaa aagagtctcc 2350

 tttccgacat gtcttctggg gctccggctc tcacacgctg ccagctttac 2400

 tggagaactt gaaactgcgt aaacaaaata acggtgcttt taatgaaacg 2450

 ctgttcagaa accagttggc tctagctact tggactattc agggagctgc 2500

 aaatgccctc tctggtgacg tttgggacat tgacaatgag ttttaaatgt 2550

 gatacccata gcttccatga gaacagcagg gtagtctggt ttctagactt 2600

 gtgctgatcg tgctaaattt tcagtagggc tacaaaacct gatgttaaaa 2650

 ttccatccca tcatcttggt actactagat gtctttaggc agcagctttt 2700

 aatacagggt agataacctg tacttcaagt taaagtgaat aaccacttaa 2750

 aaaatgtcca tgatggaata ttcccctatc tctagaattt taagtgcttt 2800

 gtaatgggaa ctgcctcttt cctgttgttg ttaatgaaaa tgtcagaaac 2850

 cagttatgtg aatgatctct ctgaatccta agggctggtc tctgctgaag 2900

 gttgtaagtg gttcgcttac tttgagtgat cctccaactt catttgatgc 2950

 taaataggag ataccaggtt gaaagacctc tccaaatgag atctaagcct 3000

 ttccataagg aatgtagcag gtttcctcat tcctgaaaga aacagttaac 3050

 tttcagaaga gatgggcttg ttttcttgcc aatgaggtct gaaatggagg 3100

 tccttctgct ggataaaatg aggttcaact gttgattgca ggaataaggc 3150

 cttaatatgt taacctcagt gtcatttatg aaaagagggg accagaagcc 3200

 aaagacttag tatattttct tttcctctgt cccttccccc ataagcctcc 3250

 atttagttct ttgttatttt tgtttcttcc aaagcacatt gaaagagaac 3300

 cagtttcagg tgtttagttg cagactcagt ttgtcagact ttaaagaata 3350

 atatgctgcc aaattttggc caaagtgtta atcttagggg agagctttct 3400

 gtccttttgg cactgagata tttattgttt atttatcagt gacagagttc 3450

 actataaatg gtgttttttt aatagaatat aattatcgga agcagtgcct 3500

 tccataatta tgacagttat actgtcggtt ttttttaaat aaaagcagca 3550

 tctgctaata aaacccaaca gatactggaa gttttgcatt tatggtcaac 3600

 acttaagggt tttagaaaac agccgtcagc caaatgtaat tgaataaagt 3650

 tgaagctaag atttagagat gaattaaatt taattagggg ttgctaagaa 3700

 gcgagcactg accagataag aatgctggtt ttcctaaatg cagtgaattg 3750

 tgaccaagtt ataaatcaat gtcacttaaa ggctgtggta gtactcctgc 3800

 aaaattttat agctcagttt atccaaggtg taactctaat tcccatttgc 3850

 aaaatttcca gtacctttgt cacaatccta acacattatc gggagcagtg 3900

 tcttccataa tgtataaaga acaaggtagt ttttacctac cacagtgtct 3950

 gtatcggaga cagtgatctc catatgttac actaagggtg taagtaatta 4000

 tcgggaacag tgtttcccat aattttcttc atgcaatgac atcttcaaag 4050

 cttgaagatc gttagtatct aacatgtatc ccaactccta taattcccta 4100

 tcttttagtt ttagttgcag aaacattttg tggtcattaa gcattgggtg 4150

 ggtaaattca accactgtaa aatgaaatta ctacaaaatt tgaaatttag 4200

 cttgggtttt tgttaccttt atggtttctc caggtcctct acttaatgag 4250

 atagcagcat acatttataa tgtttgctat tgacaagtca ttttaattta 4300

 tcacattatt tgcatgttac ctcctataaa cttagtgcgg acaagtttta 4350

 atccagaatt gaccttttga cttaaagcag agggactttg tatagaaggt 4400

 ttgggggctg tggggaagga gagtcccctg aaggtctgac acgtctgcct 4450

 acccattcgt ggtgatcaat taaatgtagg tatgaataag ttcgaagctc 4500

 cgtgagtgaa ccatcatata aacgtgtagt acagctgttt gtcatagggc 4550

 agttggaaac ggcctcctag ggaaaagttc atagggtctc ttcaggttct 4600

 tagtgtcact tacctagatt tacagcctca cttgaatgtg tcactactca 4650

 cagtctcttt aatcttcagt tttatcttta atctcctctt ttatcttgga 4700

 ctgacattta gcgtagctaa gtgaaaaggt catagctgag attcctggtt 4750

 cgggtgttac gcacacgtac ttaaatgaaa gcatgtggca tgttcatcgt 4800

 ataacacaat atgaatacag ggcatgcatt ttgcagcagt gagtctcttc 4850

 agaaaaccct tttctacagt tagggttgag ttacttccta tcaagccagt 4900

 acgtgctaac aggctcaata ttcctgaatg aaatatcaga ctagtgacaa 4950

 gctcctggtc ttgagatgtc ttctcgttaa ggagtagggc cttttggagg 5000

 taaaggtata 5010

<210> 1610
<211> 760
<212> PRT
<213> Homo sapien

<400> 1610
 Met Met Asp Gln Ala Arg Ser Ala Phe Ser Asn Leu Phe Gly Gly
   1               5                  10                  15

 Glu Pro Leu Ser Tyr Thr Arg Phe Ser Leu Ala Arg Gln Val Asp
                  20                  25                  30

 Gly Asp Asn Ser His Val Glu Met Lys Leu Ala Val Asp Glu Glu
                  35                  40                  45

 Glu Asn Ala Asp Asn Asn Thr Lys Ala Asn Val Thr Lys Pro Lys
                  50                  55                  60

 Arg Cys Ser Gly Ser Ile Cys Tyr Gly Thr Ile Ala Val Ile Val
                  65                  70                  75

 Phe Phe Leu Ile Gly Phe Met Ile Gly Tyr Leu Gly Tyr Cys Lys
                  80                  85                  90

 Gly Val Glu Pro Lys Thr Glu Cys Glu Arg Leu Ala Gly Thr Glu
                  95                 100                 105

 Ser Pro Val Arg Glu Glu Pro Gly Glu Asp Phe Pro Ala Ala Arg
                 110                 115                 120

 Arg Leu Tyr Trp Asp Asp Leu Lys Arg Lys Leu Ser Glu Lys Leu
                 125                 130                 135

 Asp Ser Thr Asp Phe Thr Ser Thr Ile Lys Leu Leu Asn Glu Asn
                 140                 145                 150

 Ser Tyr Val Pro Arg Glu Ala Gly Ser Gln Lys Asp Glu Asn Leu
                 155                 160                 165

 Ala Leu Tyr Val Glu Asn Gln Phe Arg Glu Phe Lys Leu Ser Lys
                 170                 175                 180

 Val Trp Arg Asp Gln His Phe Val Lys Ile Gln Val Lys Asp Ser
                 185                 190                 195

 Ala Gln Asn Ser Val Ile Ile Val Asp Lys Asn Gly Arg Leu Val
                 200                 205                 210

 Tyr Leu Val Glu Asn Pro Gly Gly Tyr Val Ala Tyr Ser Lys Ala
                 215                 220                 225

 Ala Thr Val Thr Gly Lys Leu Val His Ala Asn Phe Gly Thr Lys
                 230                 235                 240

 Lys Asp Phe Glu Asp Leu Tyr Thr Pro Val Asn Gly Ser Ile Val
                 245                 250                 255

 Ile Val Arg Ala Gly Lys Ile Thr Phe Ala Glu Lys Val Ala Asn
                 260                 265                 270

 Ala Glu Ser Leu Asn Ala Ile Gly Val Leu Ile Tyr Met Asp Gln
                 275                 280                 285

 Thr Lys Phe Pro Ile Val Asn Ala Glu Leu Ser Phe Phe Gly His
                 290                 295                 300

 Ala His Leu Gly Thr Gly Asp Pro Tyr Thr Pro Gly Phe Pro Ser
                 305                 310                 315

 Phe Asn His Thr Gln Phe Pro Pro Ser Arg Ser Ser Gly Leu Pro
                 320                 325                 330

 Asn Ile Pro Val Gln Thr Ile Ser Arg Ala Ala Ala Glu Lys Leu
                 335                 340                 345

 Phe Gly Asn Met Glu Gly Asp Cys Pro Ser Asp Trp Lys Thr Asp
                 350                 355                 360

 Ser Thr Cys Arg Met Val Thr Ser Glu Ser Lys Asn Val Lys Leu
                 365                 370                 375

 Thr Val Ser Asn Val Leu Lys Glu Ile Lys Ile Leu Asn Ile Phe
                 380                 385                 390

 Gly Val Ile Lys Gly Phe Val Glu Pro Asp His Tyr Val Val Val
                 395                 400                 405

 Gly Ala Gln Arg Asp Ala Trp Gly Pro Gly Ala Ala Lys Ser Gly
                 410                 415                 420

 Val Gly Thr Ala Leu Leu Leu Lys Leu Ala Gln Met Phe Ser Asp
                 425                 430                 435

 Met Val Leu Lys Asp Gly Phe Gln Pro Ser Arg Ser Ile Ile Phe
                 440                 445                 450

 Ala Ser Trp Ser Ala Gly Asp Phe Gly Ser Val Gly Ala Thr Glu
                 455                 460                 465

 Trp Leu Glu Gly Tyr Leu Ser Ser Leu His Leu Lys Ala Phe Thr
                 470                 475                 480

 Tyr Ile Asn Leu Asp Lys Ala Val Leu Gly Thr Ser Asn Phe Lys
                 485                 490                 495

 Val Ser Ala Ser Pro Leu Leu Tyr Thr Leu Ile Glu Lys Thr Met
                 500                 505                 510

 Gln Asn Val Lys His Pro Val Thr Gly Gln Phe Leu Tyr Gln Asp
                 515                 520                 525

 Ser Asn Trp Ala Ser Lys Val Glu Lys Leu Thr Leu Asp Asn Ala
                 530                 535                 540

 Ala Phe Pro Phe Leu Ala Tyr Ser Gly Ile Pro Ala Val Ser Phe
                 545                 550                 555

 Cys Phe Cys Glu Asp Thr Asp Tyr Pro Tyr Leu Gly Thr Thr Met
                 560                 565                 570

 Asp Thr Tyr Lys Glu Leu Ile Glu Arg Ile Pro Glu Leu Asn Lys
                 575                 580                 585

 Val Ala Arg Ala Ala Ala Glu Val Ala Gly Gln Phe Val Ile Lys
                 590                 595                 600

 Leu Thr His Asp Val Glu Leu Asn Leu Asp Tyr Glu Arg Tyr Asn
                 605                 610                 615

 Ser Gln Leu Leu Ser Phe Val Arg Asp Leu Asn Gln Tyr Arg Ala
                 620                 625                 630

 Asp Ile Lys Glu Met Gly Leu Ser Leu Gln Trp Leu Tyr Ser Ala
                 635                 640                 645

 Arg Gly Asp Phe Phe Arg Ala Thr Ser Arg Leu Thr Thr Asp Phe
                 650                 655                 660

 Gly Asn Ala Glu Lys Thr Asp Arg Phe Val Met Lys Lys Leu Asn
                 665                 670                 675

 Asp Arg Val Met Arg Val Glu Tyr His Phe Leu Ser Pro Tyr Val
                 680                 685                 690

 Ser Pro Lys Glu Ser Pro Phe Arg His Val Phe Trp Gly Ser Gly
                 695                 700                 705

 Ser His Thr Leu Pro Ala Leu Leu Glu Asn Leu Lys Leu Arg Lys
                 710                 715                 720

 Gln Asn Asn Gly Ala Phe Asn Glu Thr Leu Phe Arg Asn Gln Leu
                 725                 730                 735

 Ala Leu Ala Thr Trp Thr Ile Gln Gly Ala Ala Asn Ala Leu Ser
                 740                 745                 750

 Gly Asp Val Trp Asp Ile Asp Asn Glu Phe
                 755                 760

<210> 1611
<211> 2090
<212> DNA
<213> Homo sapien

<400> 1611
 gttggcgagg agtttcctgt ttcccccgca gcgctgagtt gaagttgagt 50

 gagtcactcg cgcgcacgga gcgacgacac ccccgcgcgt gcacccgctc 100

 gggacaggag ccggactcct gtgcagcttc cctcggccgc cgggggcctc 150

 cccgcgcctc gccggcctcc aggcccctcc tggctggcga gcgggcgcca 200

 catctggccc gcacatctgc gctgccggcc cggcgcgggg tccggagagg 250

 gcgcggcgcg gagcgcagcc aggggtccgg gaaggcgccg tccgtgcgct 300

 gggggctcgg tctatgacga gcagcggggt ctgccatggg tcgggggctg 350

 ctcaggggcc tgtggccgct gcacatcgtc ctgtggacgc gtatcgccag 400

 cacgatccca ccgcacgttc agaagtcggt taataacgac atgatagtca 450

 ctgacaacaa cggtgcagtc aagtttccac aactgtgtaa attttgtgat 500

 gtgagatttt ccacctgtga caaccagaaa tcctgcatga gcaactgcag 550

 catcacctcc atctgtgaga agccacagga agtctgtgtg gctgtatgga 600

 gaaagaatga cgagaacata acactagaga cagtttgcca tgaccccaag 650

 ctcccctacc atgactttat tctggaagat gctgcttctc caaagtgcat 700

 tatgaaggaa aaaaaaaagc ctggtgagac tttcttcatg tgttcctgta 750

 gctctgatga gtgcaatgac aacatcatct tctcagaaga atataacacc 800

 agcaatcctg acttgttgct agtcatattt caagtgacag gcatcagcct 850

 cctgccacca ctgggagttg ccatatctgt catcatcatc ttctactgct 900

 accgcgttaa ccggcagcag aagctgagtt caacctggga aaccggcaag 950

 acgcggaagc tcatggagtt cagcgagcac tgtgccatca tcctggaaga 1000

 tgaccgctct gacatcagct ccacgtgtgc caacaacatc aaccacaaca 1050

 cagagctgct gcccattgag ctggacaccc tggtggggaa aggtcgcttt 1100

 gctgaggtct ataaggccaa gctgaagcag aacacttcag agcagtttga 1150

 gacagtggca gtcaagatct ttccctatga ggagtatgcc tcttggaaga 1200

 cagagaagga catcttctca gacatcaatc tgaagcatga gaacatactc 1250

 cagttcctga cggctgagga gcggaagacg gagttgggga aacaatactg 1300

 gctgatcacc gccttccacg ccaagggcaa cctacaggag tacctgacgc 1350

 ggcatgtcat cagctgggag gacctgcgca agctgggcag ctccctcgcc 1400

 cgggggattg ctcacctcca cagtgatcac actccatgtg ggaggcccaa 1450

 gatgcccatc gtgcacaggg acctcaagag ctccaatatc ctcgtgaaga 1500

 acgacctaac ctgctgcctg tgtgactttg ggctttccct gcgtctggac 1550

 cctactctgt ctgtggatga cctggctaac agtgggcagg tgggaactgc 1600

 aagatacatg gctccagaag tcctagaatc caggatgaat ttggagaatg 1650

 ctgagtcctt caagcagacc gatgtctact ccatggctct ggtgctctgg 1700

 gaaatgacat ctcgctgtaa tgcagtggga gaagtaaaag attatgagcc 1750

 tccatttggt tccaaggtgc gggagcaccc ctgtgtcgaa agcatgaagg 1800

 acaacgtgtt gagagatcga gggcgaccag aaattcccag cttctggctc 1850

 aaccaccagg gcatccagat ggtgtgtgag acgttgactg agtgctggga 1900

 ccacgaccca gaggcccgtc tcacagccca gtgtgtggca gaacgcttca 1950

 gtgagctgga gcatctggac aggctctcgg ggaggagctg ctcggaggag 2000

 aagattcctg aagacggctc cctaaacact accaaatagc tcttatgggg 2050

 caggctgggc atgtccaaag aggctgcccc tctcaccaaa 2090

<210> 1612
<211> 567
<212> PRT
<213> Homo sapien

<400> 1612
 Met Gly Arg Gly Leu Leu Arg Gly Leu Trp Pro Leu His Ile Val
   1               5                  10                  15

 Leu Trp Thr Arg Ile Ala Ser Thr Ile Pro Pro His Val Gln Lys
                  20                  25                  30

 Ser Val Asn Asn Asp Met Ile Val Thr Asp Asn Asn Gly Ala Val
                  35                  40                  45

 Lys Phe Pro Gln Leu Cys Lys Phe Cys Asp Val Arg Phe Ser Thr
                  50                  55                  60

 Cys Asp Asn Gln Lys Ser Cys Met Ser Asn Cys Ser Ile Thr Ser
                  65                  70                  75

 Ile Cys Glu Lys Pro Gln Glu Val Cys Val Ala Val Trp Arg Lys
                  80                  85                  90

 Asn Asp Glu Asn Ile Thr Leu Glu Thr Val Cys His Asp Pro Lys
                  95                 100                 105

 Leu Pro Tyr His Asp Phe Ile Leu Glu Asp Ala Ala Ser Pro Lys
                 110                 115                 120

 Cys Ile Met Lys Glu Lys Lys Lys Pro Gly Glu Thr Phe Phe Met
                 125                 130                 135

 Cys Ser Cys Ser Ser Asp Glu Cys Asn Asp Asn Ile Ile Phe Ser
                 140                 145                 150

 Glu Glu Tyr Asn Thr Ser Asn Pro Asp Leu Leu Leu Val Ile Phe
                 155                 160                 165

 Gln Val Thr Gly Ile Ser Leu Leu Pro Pro Leu Gly Val Ala Ile
                 170                 175                 180

 Ser Val Ile Ile Ile Phe Tyr Cys Tyr Arg Val Asn Arg Gln Gln
                 185                 190                 195

 Lys Leu Ser Ser Thr Trp Glu Thr Gly Lys Thr Arg Lys Leu Met
                 200                 205                 210

 Glu Phe Ser Glu His Cys Ala Ile Ile Leu Glu Asp Asp Arg Ser
                 215                 220                 225

 Asp Ile Ser Ser Thr Cys Ala Asn Asn Ile Asn His Asn Thr Glu
                 230                 235                 240

 Leu Leu Pro Ile Glu Leu Asp Thr Leu Val Gly Lys Gly Arg Phe
                 245                 250                 255

 Ala Glu Val Tyr Lys Ala Lys Leu Lys Gln Asn Thr Ser Glu Gln
                 260                 265                 270

 Phe Glu Thr Val Ala Val Lys Ile Phe Pro Tyr Glu Glu Tyr Ala
                 275                 280                 285

 Ser Trp Lys Thr Glu Lys Asp Ile Phe Ser Asp Ile Asn Leu Lys
                 290                 295                 300

 His Glu Asn Ile Leu Gln Phe Leu Thr Ala Glu Glu Arg Lys Thr
                 305                 310                 315

 Glu Leu Gly Lys Gln Tyr Trp Leu Ile Thr Ala Phe His Ala Lys
                 320                 325                 330

 Gly Asn Leu Gln Glu Tyr Leu Thr Arg His Val Ile Ser Trp Glu
                 335                 340                 345

 Asp Leu Arg Lys Leu Gly Ser Ser Leu Ala Arg Gly Ile Ala His
                 350                 355                 360

 Leu His Ser Asp His Thr Pro Cys Gly Arg Pro Lys Met Pro Ile
                 365                 370                 375

 Val His Arg Asp Leu Lys Ser Ser Asn Ile Leu Val Lys Asn Asp
                 380                 385                 390

 Leu Thr Cys Cys Leu Cys Asp Phe Gly Leu Ser Leu Arg Leu Asp
                 395                 400                 405

 Pro Thr Leu Ser Val Asp Asp Leu Ala Asn Ser Gly Gln Val Gly
                 410                 415                 420

 Thr Ala Arg Tyr Met Ala Pro Glu Val Leu Glu Ser Arg Met Asn
                 425                 430                 435

 Leu Glu Asn Ala Glu Ser Phe Lys Gln Thr Asp Val Tyr Ser Met
                 440                 445                 450

 Ala Leu Val Leu Trp Glu Met Thr Ser Arg Cys Asn Ala Val Gly
                 455                 460                 465

 Glu Val Lys Asp Tyr Glu Pro Pro Phe Gly Ser Lys Val Arg Glu
                 470                 475                 480

 His Pro Cys Val Glu Ser Met Lys Asp Asn Val Leu Arg Asp Arg
                 485                 490                 495

 Gly Arg Pro Glu Ile Pro Ser Phe Trp Leu Asn His Gln Gly Ile
                 500                 505                 510

 Gln Met Val Cys Glu Thr Leu Thr Glu Cys Trp Asp His Asp Pro
                 515                 520                 525

 Glu Ala Arg Leu Thr Ala Gln Cys Val Ala Glu Arg Phe Ser Glu
                 530                 535                 540

 Leu Glu His Leu Asp Arg Leu Ser Gly Arg Ser Cys Ser Glu Glu
                 545                 550                 555

 Lys Ile Pro Glu Asp Gly Ser Leu Asn Thr Thr Lys
                 560                 565

<210> 1613
<211> 894
<212> DNA
<213> Homo sapien

<400> 1613
 cagtctcaat gggggcactg gggctggagg gcaggggtgg gaggctccag 50

 gggaggggtt ccctcctgct agctgtggca ggagccactt ctctggtgac 100

 cttgttgctg gcggtgccta tcactgtcct ggctgtgctg gccttagtgc 150

 cccaggatca gggaggactg gtaacggaga cggccgaccc cggggcacag 200

 gcccagcaag gactggggtt tcagaagctg ccagaggagg agccagaaac 250

 agatctcagc cccgggctcc cagctgccca cctcataggc gctccgctga 300

 aggggcaggg gctaggctgg gagacgacga aggaacaggc gtttctgacg 350

 agcgggacgc agttctcgga cgccgagggg ctggcgctcc cgcaggacgg 400

 cctctattac ctctactgtc tcgtcggcta ccggggccgg gcgccccctg 450

 gcggcgggga cccccagggc cgctcggtca cgctgcgcag ctctctgtac 500

 cgggcggggg gcgcctacgg gccgggcact cccgagctgc tgctcgaggg 550

 cgccgagacg gtgactccag tgctggaccc ggccaggaga caagggtacg 600

 ggcctctctg gtacacgagc gtggggttcg gcggcctggt gcagctccgg 650

 aggggcgaga gggtgtacgt caacatcagt caccccgata tggtggactt 700

 cgcgagaggg aagaccttct ttggggccgt gatggtgggg tgagggaata 750

 tgagtgcgtg gtgcgagtgc gtgaatattg ggggcccgga cgcccaggac 800

 cccatggcag tgggaaaaat gtaggagact gtttggaaat tgattttgaa 850

 cctgatgaaa ataaagaatg gaaagcttca gtgctgccga taaa 894

<210> 1614
<211> 244
<212> PRT
<213> Homo sapien

<400> 1614
 Met Gly Ala Leu Gly Leu Glu Gly Arg Gly Gly Arg Leu Gln Gly
   1               5                  10                  15

 Arg Gly Ser Leu Leu Leu Ala Val Ala Gly Ala Thr Ser Leu Val
                  20                  25                  30

 Thr Leu Leu Leu Ala Val Pro Ile Thr Val Leu Ala Val Leu Ala
                  35                  40                  45

 Leu Val Pro Gln Asp Gln Gly Gly Leu Val Thr Glu Thr Ala Asp
                  50                  55                  60

 Pro Gly Ala Gln Ala Gln Gln Gly Leu Gly Phe Gln Lys Leu Pro
                  65                  70                  75

 Glu Glu Glu Pro Glu Thr Asp Leu Ser Pro Gly Leu Pro Ala Ala
                  80                  85                  90

 His Leu Ile Gly Ala Pro Leu Lys Gly Gln Gly Leu Gly Trp Glu
                  95                 100                 105

 Thr Thr Lys Glu Gln Ala Phe Leu Thr Ser Gly Thr Gln Phe Ser
                 110                 115                 120

 Asp Ala Glu Gly Leu Ala Leu Pro Gln Asp Gly Leu Tyr Tyr Leu
                 125                 130                 135

 Tyr Cys Leu Val Gly Tyr Arg Gly Arg Ala Pro Pro Gly Gly Gly
                 140                 145                 150

 Asp Pro Gln Gly Arg Ser Val Thr Leu Arg Ser Ser Leu Tyr Arg
                 155                 160                 165

 Ala Gly Gly Ala Tyr Gly Pro Gly Thr Pro Glu Leu Leu Leu Glu
                 170                 175                 180

 Gly Ala Glu Thr Val Thr Pro Val Leu Asp Pro Ala Arg Arg Gln
                 185                 190                 195

 Gly Tyr Gly Pro Leu Trp Tyr Thr Ser Val Gly Phe Gly Gly Leu
                 200                 205                 210

 Val Gln Leu Arg Arg Gly Glu Arg Val Tyr Val Asn Ile Ser His
                 215                 220                 225

 Pro Asp Met Val Asp Phe Ala Arg Gly Lys Thr Phe Phe Gly Ala
                 230                 235                 240

 Val Met Val Gly


<210> 1615
<211> 1592
<212> DNA
<213> Homo sapien

<400> 1615
 ggagagatga tgagttgctg agtgtgcaca cctttccgga acacatacac 50

 acaccctgct ctgggatccc ttgtgaggct gccctcatgg agttccccct 100

 ggcccagata tgtccccaag ggagtcacga agcccccatc ccaaccttca 150

 gcaccttcca gatcacagac atgacccgca ggagctgcca gaacctgggc 200

 tacactgcgg catctcccca ggccccggag gctgcctcca gcacagggaa 250

 tgctgagagg gcagaggagg tgcctggaga aggaagcctg ttcctgcagg 300

 ccgagacccg ggcttggttc cagaagaccc aggcccactg gctcctgcag 350

 cacggggcag cccctgcctg gttccatggc ttcatcaccc ggagggaggc 400

 agagaggctg ctggagccca agcctcaggg gtgctacttg gtgcggttca 450

 gcgagagcgc ggtgaccttc gtgctgactt acaggagccg gacttgctgc 500

 cgccacttcc tgctggccca gctcagggac gggcgccacg tggtgctggg 550

 cgaggacagc gcccacgcgc ggctgcagga cctgctgctg cactacaccg 600

 cgcacccgct cagcccctac ggggagacgc tcaccgagcc cctcgcccga 650

 cagactcctg agcctgcagg actttccctg aggaccgaag aatcaaactt 700

 tggaagcaaa agccaggacc caaaccccca gtacagccca atcatcaaac 750

 aggggcaagc cccagtcccg atgcagaaag agggggccgg ggagaaggag 800

 ccctcccagc tgctcaggcc caagcctccc atccccgcca aacctcagct 850

 gcccccagaa gtctacacaa tccctgttcc acgacaccgc ccggccccac 900

 gccccaagcc ctccaatcct atctacaatg agcctgatga acccatagct 950

 ttctatgcca tgggccgggg cagccctggg gaagccccca gcaacatcta 1000

 tgtggaagtg gaagatgagg gcctacccgc cacccttggg caccctgtcc 1050

 tacggaagag ctggtccagg cctgtcccag gaggccagaa tacaggtggc 1100

 tcccagctgc attctgagaa ctctgtgatt gggcaaggcc ctcccctgcc 1150

 ccaccagccc ccacccgcct ggagacacac cctcccccac aatctttcta 1200

 gacaggtgct tcaggacaga ggacaggcat ggcttcccct tgggcctcct 1250

 cagtaggcgg tctggcctga cccccaacaa agaagcctgg aggtcagaga 1300

 agcaaatgcg gagcctgctc cctcctaaga agatcccaag aatccaatgg 1350

 ctcagtcctt ggtgatctaa gacagcaaag aagtgtgcaa ggagggccct 1400

 gttagctccc actgtcctgg tttctcctcc tggagtctaa tttccttggc 1450

 cctctgagcc ttttgagtct gggccctggt ccaatgctgc tgttgtctga 1500

 ggaatggttt ggtgagaaca gatgttagaa cttgtttgtt gattcttgtc 1550

 tggctaataa atcatcacca actgccttct cctacaggga aa 1592

<210> 1616
<211> 389
<212> PRT
<213> Homo sapien

<400> 1616
 Met Glu Phe Pro Leu Ala Gln Ile Cys Pro Gln Gly Ser His Glu
   1               5                  10                  15

 Ala Pro Ile Pro Thr Phe Ser Thr Phe Gln Ile Thr Asp Met Thr
                  20                  25                  30

 Arg Arg Ser Cys Gln Asn Leu Gly Tyr Thr Ala Ala Ser Pro Gln
                  35                  40                  45

 Ala Pro Glu Ala Ala Ser Ser Thr Gly Asn Ala Glu Arg Ala Glu
                  50                  55                  60

 Glu Val Pro Gly Glu Gly Ser Leu Phe Leu Gln Ala Glu Thr Arg
                  65                  70                  75

 Ala Trp Phe Gln Lys Thr Gln Ala His Trp Leu Leu Gln His Gly
                  80                  85                  90

 Ala Ala Pro Ala Trp Phe His Gly Phe Ile Thr Arg Arg Glu Ala
                  95                 100                 105

 Glu Arg Leu Leu Glu Pro Lys Pro Gln Gly Cys Tyr Leu Val Arg
                 110                 115                 120

 Phe Ser Glu Ser Ala Val Thr Phe Val Leu Thr Tyr Arg Ser Arg
                 125                 130                 135

 Thr Cys Cys Arg His Phe Leu Leu Ala Gln Leu Arg Asp Gly Arg
                 140                 145                 150

 His Val Val Leu Gly Glu Asp Ser Ala His Ala Arg Leu Gln Asp
                 155                 160                 165

 Leu Leu Leu His Tyr Thr Ala His Pro Leu Ser Pro Tyr Gly Glu
                 170                 175                 180

 Thr Leu Thr Glu Pro Leu Ala Arg Gln Thr Pro Glu Pro Ala Gly
                 185                 190                 195

 Leu Ser Leu Arg Thr Glu Glu Ser Asn Phe Gly Ser Lys Ser Gln
                 200                 205                 210

 Asp Pro Asn Pro Gln Tyr Ser Pro Ile Ile Lys Gln Gly Gln Ala
                 215                 220                 225

 Pro Val Pro Met Gln Lys Glu Gly Ala Gly Glu Lys Glu Pro Ser
                 230                 235                 240

 Gln Leu Leu Arg Pro Lys Pro Pro Ile Pro Ala Lys Pro Gln Leu
                 245                 250                 255

 Pro Pro Glu Val Tyr Thr Ile Pro Val Pro Arg His Arg Pro Ala
                 260                 265                 270

 Pro Arg Pro Lys Pro Ser Asn Pro Ile Tyr Asn Glu Pro Asp Glu
                 275                 280                 285

 Pro Ile Ala Phe Tyr Ala Met Gly Arg Gly Ser Pro Gly Glu Ala
                 290                 295                 300

 Pro Ser Asn Ile Tyr Val Glu Val Glu Asp Glu Gly Leu Pro Ala
                 305                 310                 315

 Thr Leu Gly His Pro Val Leu Arg Lys Ser Trp Ser Arg Pro Val
                 320                 325                 330

 Pro Gly Gly Gln Asn Thr Gly Gly Ser Gln Leu His Ser Glu Asn
                 335                 340                 345

 Ser Val Ile Gly Gln Gly Pro Pro Leu Pro His Gln Pro Pro Pro
                 350                 355                 360

 Ala Trp Arg His Thr Leu Pro His Asn Leu Ser Arg Gln Val Leu
                 365                 370                 375

 Gln Asp Arg Gly Gln Ala Trp Leu Pro Leu Gly Pro Pro Gln
                 380                 385

<210> 1617
<211> 947
<212> DNA
<213> Homo sapien

<400> 1617
 ggctcggggc cggggccagc acccacactg ggtctccaca gcggcatgga 50

 ggcctgcgtg tcttcactgc tggtgctggc cctgggggcc ctgtcagtag 100

 gcagctcctt tgggacccag atcatcgggg gccgggaggt gatcccccac 150

 tcgcgcccgt acatggcctc actgcagaga aatggctccc acctgtgcgg 200

 gggtgtcctg gtgcacccaa agtgggtgct gacggctgcc cactgcctgg 250

 cccagcggat ggcccagctg aggctggtgc tggggctcca caccctggac 300

 agccccggtc tcaccttcca catcaaggca gccatccagc accctcgcta 350

 caagcccgtc cctgccctgg agaacgacct cgcgctgctt cagctggacg 400

 ggaaagtgaa gcccagccgg accatccggc cgttggccct gcccagtaag 450

 cgccaggtgg tggcagcagg gactcggtgc agcatggccg gctgggggct 500

 gacccaccag ggcgggcgcc tgtcccgggt gctgcgggag ctggacctcc 550

 aagtgctgga cacccgcatg tgtaacaaca gccgcttctg gaacggcagc 600

 ctctccccca gcatggtctg cctggcggcc gactccaagg accaggctcc 650

 ctgcaagggt gactcgggcg ggcccctggt gtgtggcaaa ggccgggtgt 700

 tggccggagt cctgtccttc agctccaggg tctgcactga catcttcaag 750

 cctcccgtgg ccaccgctgt ggcgccttac gtgtcctgga tcaggaaggt 800

 caccggccga tcggcctgat gccctggggt gatggggacc ccctcgctgt 850

 ctccacagga cccttcccct ccaggggtgc agtggggtgg gtgaggacgg 900

 gtgggaggga cagggaggga ccaataaatc ataatgaaga aacgctc 947

<210> 1618
<211> 257
<212> PRT
<213> Homo sapien

<400> 1618
 Met Glu Ala Cys Val Ser Ser Leu Leu Val Leu Ala Leu Gly Ala
   1               5                  10                  15

 Leu Ser Val Gly Ser Ser Phe Gly Thr Gln Ile Ile Gly Gly Arg
                  20                  25                  30

 Glu Val Ile Pro His Ser Arg Pro Tyr Met Ala Ser Leu Gln Arg
                  35                  40                  45

 Asn Gly Ser His Leu Cys Gly Gly Val Leu Val His Pro Lys Trp
                  50                  55                  60

 Val Leu Thr Ala Ala His Cys Leu Ala Gln Arg Met Ala Gln Leu
                  65                  70                  75

 Arg Leu Val Leu Gly Leu His Thr Leu Asp Ser Pro Gly Leu Thr
                  80                  85                  90

 Phe His Ile Lys Ala Ala Ile Gln His Pro Arg Tyr Lys Pro Val
                  95                 100                 105

 Pro Ala Leu Glu Asn Asp Leu Ala Leu Leu Gln Leu Asp Gly Lys
                 110                 115                 120

 Val Lys Pro Ser Arg Thr Ile Arg Pro Leu Ala Leu Pro Ser Lys
                 125                 130                 135

 Arg Gln Val Val Ala Ala Gly Thr Arg Cys Ser Met Ala Gly Trp
                 140                 145                 150

 Gly Leu Thr His Gln Gly Gly Arg Leu Ser Arg Val Leu Arg Glu
                 155                 160                 165

 Leu Asp Leu Gln Val Leu Asp Thr Arg Met Cys Asn Asn Ser Arg
                 170                 175                 180

 Phe Trp Asn Gly Ser Leu Ser Pro Ser Met Val Cys Leu Ala Ala
                 185                 190                 195

 Asp Ser Lys Asp Gln Ala Pro Cys Lys Gly Asp Ser Gly Gly Pro
                 200                 205                 210

 Leu Val Cys Gly Lys Gly Arg Val Leu Ala Gly Val Leu Ser Phe
                 215                 220                 225

 Ser Ser Arg Val Cys Thr Asp Ile Phe Lys Pro Pro Val Ala Thr
                 230                 235                 240

 Ala Val Ala Pro Tyr Val Ser Trp Ile Arg Lys Val Thr Gly Arg
                 245                 250                 255

 Ser Ala


<210> 1619
<211> 1318
<212> DNA
<213> Homo sapien

<400> 1619
 ctcctctagg ccgccggccg cgaagcgctg agtcacggtg aggcgactgg 50

 acccacactc tcttaacctg ccctccctgc actcgctccc ggcggctctt 100

 cgcgtcaccc ccgccgctaa ggctccaggt gccgctaccg cagcgtgagt 150

 acctggggct cctgcagggg tccactagcc ctccatcctc tacagctcag 200

 catcagaaca ctctcttttt agactccgat atggggtcct ccaagaaagt 250

 tactctctca gtgctcagcc gggagcagtc ggaaggggtt ggagcgaggg 300

 tccggagaag cattggcaga cccgagttaa aaaatctgga tccgttttta 350

 ctgtttgatg aatttaaagg aggtagacca ggaggatttc ctgatcatcc 400

 acatcgaggt tttgaaacag tatcctacct cctggaaggg ggcagcatgg 450

 cccatgaaga cttctgtgga cacactggta aaatgaaccc aggagatttg 500

 cagtggatga ctgcgggccg gggcattctg cacgctgaga tgccttgctc 550

 agaggagcca gcccatggcc tacaactgtg ggttaatttg aggagctcag 600

 agaagatggt ggagcctcag taccaggaac tgaaaagtga agaaatccct 650

 aaacccagta aggatggtgt gacagttgct gtcatttctg gagaagccct 700

 gggaataaag tccaaggttt acactcgcac accaacctta tatttggact 750

 tcaaattgga cccaggagcc aaacattccc aacctatccc taaagggtgg 800

 acaagcttca tttacacgat atctggagat gtgtatattg ggcccgatga 850

 tgcacaacaa aaaatagaac ctcatcacac agcagtgctt ggagaaggtg 900

 acagtgtcca ggtggagaac aaggatccca agagaagcca ctttgtctta 950

 attgctgggg agccattaag agaaccagtt atccaacatg gtccatttgt 1000

 gatgaacacc aatgaagaga tttctcaagc tattcttgat ttcagaaacg 1050

 caaaaaatgg gtttgaaagg gccaaaacct ggaaatcaaa gattgggaac 1100

 tagtggaaag cggaagagca ggtcttgatg tgtcctagaa ttttgccatt 1150

 tctgagattg agccattgaa ggcattccat ttctaaagct tatttagccg 1200

 gtgcttctaa agaattccac actaacgtga taacatggtt tttgtaacaa 1250

 taaatgtagg atatttcctg gcacatgcaa ataaacctaa tcattgtttc 1300

 tttaaaaaaa aaaaaaaa 1318

<210> 1620
<211> 290
<212> PRT
<213> Homo sapien

<400> 1620
 Met Gly Ser Ser Lys Lys Val Thr Leu Ser Val Leu Ser Arg Glu
   1               5                  10                  15

 Gln Ser Glu Gly Val Gly Ala Arg Val Arg Arg Ser Ile Gly Arg
                  20                  25                  30

 Pro Glu Leu Lys Asn Leu Asp Pro Phe Leu Leu Phe Asp Glu Phe
                  35                  40                  45

 Lys Gly Gly Arg Pro Gly Gly Phe Pro Asp His Pro His Arg Gly
                  50                  55                  60

 Phe Glu Thr Val Ser Tyr Leu Leu Glu Gly Gly Ser Met Ala His
                  65                  70                  75

 Glu Asp Phe Cys Gly His Thr Gly Lys Met Asn Pro Gly Asp Leu
                  80                  85                  90

 Gln Trp Met Thr Ala Gly Arg Gly Ile Leu His Ala Glu Met Pro
                  95                 100                 105

 Cys Ser Glu Glu Pro Ala His Gly Leu Gln Leu Trp Val Asn Leu
                 110                 115                 120

 Arg Ser Ser Glu Lys Met Val Glu Pro Gln Tyr Gln Glu Leu Lys
                 125                 130                 135

 Ser Glu Glu Ile Pro Lys Pro Ser Lys Asp Gly Val Thr Val Ala
                 140                 145                 150

 Val Ile Ser Gly Glu Ala Leu Gly Ile Lys Ser Lys Val Tyr Thr
                 155                 160                 165

 Arg Thr Pro Thr Leu Tyr Leu Asp Phe Lys Leu Asp Pro Gly Ala
                 170                 175                 180

 Lys His Ser Gln Pro Ile Pro Lys Gly Trp Thr Ser Phe Ile Tyr
                 185                 190                 195

 Thr Ile Ser Gly Asp Val Tyr Ile Gly Pro Asp Asp Ala Gln Gln
                 200                 205                 210

 Lys Ile Glu Pro His His Thr Ala Val Leu Gly Glu Gly Asp Ser
                 215                 220                 225

 Val Gln Val Glu Asn Lys Asp Pro Lys Arg Ser His Phe Val Leu
                 230                 235                 240

 Ile Ala Gly Glu Pro Leu Arg Glu Pro Val Ile Gln His Gly Pro
                 245                 250                 255

 Phe Val Met Asn Thr Asn Glu Glu Ile Ser Gln Ala Ile Leu Asp
                 260                 265                 270

 Phe Arg Asn Ala Lys Asn Gly Phe Glu Arg Ala Lys Thr Trp Lys
                 275                 280                 285

 Ser Lys Ile Gly Asn
                 290

<210> 1621
<211> 1904
<212> DNA
<213> Homo sapien

<400> 1621
 attgaaaatg aattttttgt attcaccaga tattcttata tgagaagatc 50

 tattttaaac agtctaaata ttttttcttc tgttggacca gcatggcagg 100

 atttaagcga gggtatgatg gaaagattgc tggattatat gatctggata 150

 aaaccttggg tcgaggccat tttgccgtgg ttaaacttgc caggcatgtc 200

 tttacgggtg aaaaggtggc agtaaaagtt attgacaaga caaaactgga 250

 cactctagct actggtcatc ttttccagga agtgagatgc atgaaactag 300

 tgcagcatcc taacatcgtc cgcctttatg aagttattga cacccagacc 350

 aaactatatc ttattctaga acttggggat ggaggagata tgtttgatta 400

 tataatgaaa catgaggagg gtcttaatga agacttggcc aagaagtatt 450

 ttgctcagat agttcatgct atatcttatt gccataaact ccatgtggtt 500

 cacagagact taaaaccaga gaatgtagtc ttctttgaaa aacaaggtct 550

 tgtaaagttg acagactttg ggttcagcaa caaatttcaa ccagggaaga 600

 agctcactac aagctgtgga tctcttgcat attccgctcc agaaattctg 650

 cttggtgatg agtatgatgc acctgcagta gatatttgga gtctgggagt 700

 gatccttttc atgttggtgt gtgagcagcc gccctttcaa gaagccaatg 750

 acagtgaaac actgacaatg atcatggatt gcaaatatac agtaccatcc 800

 catgtgtcta aagagtgtaa agagtaagta aaacaaagta tgtggaaacc 850

 ttaaggactc agattaaaac cagaagtttt aattccatta atatgtcaag 900

 aaaatttgag aggacttcaa acatccaagc atctgggttg attttaattt 950

 ttgaatttaa tatttctgct gttgtttcag agtgttcggt cggcgggggt 1000

 gggggtggtt agcccctgaa tatgatctga aatttaatat tagagtacaa 1050

 aatgtattca tctatttctt attcaagaaa tctattacat gcctcttcaa 1100

 ccttcaggag tggtggttat ttcacttgaa ctgaagaaat accatgggaa 1150

 ctacctttct ctgcatgagc aaaaagcaag atcacctgga attgttttaa 1200

 gttccagaga agagttaggg cattttcttt cctgaataga ccatcaacac 1250

 actattttag ggtttacata gtatgtctca taattttctt cacacacctt 1300

 ctgctaattg actaaagagc tgtttaggtt tatgtgacta tgggaagcca 1350

 gcataaaaag tatactcaat tatttggaat ttaaagtagt acatagtact 1400

 atgatatgtg tagtgagaaa tacagtaatg gaatagaact gttggaagtt 1450

 cagtattgac attttaagtg acatttttta atgagctcag ctgagattat 1500

 agccactact tacaggactt tgctgtagaa acagagtttt gagtttctcc 1550

 tatcagctgg taagaaggaa atctgattgc ccaaggactt tttttctcta 1600

 aatgaagccc catctcaggt ggatgtttaa gaacttaggt attcaaggcc 1650

 gaggcaggca gatcacaagg tcaggagatc gagaccatcc tgacttacat 1700

 ggtgaaaccc cgtctctact aaaaatacag aaaattacct gggcgcctgt 1750

 agttccagct actcaggagg ctgaggcggg agaatggcgt gaaccctgga 1800

 ggtggagctt gcagtgagcc gagatcgcgc cactgcattc cagcctgggc 1850

 gacagagcga gactctgtct caaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1900

 aaaa 1904

<210> 1622
<211> 244
<212> PRT
<213> Homo sapien

<400> 1622
 Met Ala Gly Phe Lys Arg Gly Tyr Asp Gly Lys Ile Ala Gly Leu
   1               5                  10                  15

 Tyr Asp Leu Asp Lys Thr Leu Gly Arg Gly His Phe Ala Val Val
                  20                  25                  30

 Lys Leu Ala Arg His Val Phe Thr Gly Glu Lys Val Ala Val Lys
                  35                  40                  45

 Val Ile Asp Lys Thr Lys Leu Asp Thr Leu Ala Thr Gly His Leu
                  50                  55                  60

 Phe Gln Glu Val Arg Cys Met Lys Leu Val Gln His Pro Asn Ile
                  65                  70                  75

 Val Arg Leu Tyr Glu Val Ile Asp Thr Gln Thr Lys Leu Tyr Leu
                  80                  85                  90

 Ile Leu Glu Leu Gly Asp Gly Gly Asp Met Phe Asp Tyr Ile Met
                  95                 100                 105

 Lys His Glu Glu Gly Leu Asn Glu Asp Leu Ala Lys Lys Tyr Phe
                 110                 115                 120

 Ala Gln Ile Val His Ala Ile Ser Tyr Cys His Lys Leu His Val
                 125                 130                 135

 Val His Arg Asp Leu Lys Pro Glu Asn Val Val Phe Phe Glu Lys
                 140                 145                 150

 Gln Gly Leu Val Lys Leu Thr Asp Phe Gly Phe Ser Asn Lys Phe
                 155                 160                 165

 Gln Pro Gly Lys Lys Leu Thr Thr Ser Cys Gly Ser Leu Ala Tyr
                 170                 175                 180

 Ser Ala Pro Glu Ile Leu Leu Gly Asp Glu Tyr Asp Ala Pro Ala
                 185                 190                 195

 Val Asp Ile Trp Ser Leu Gly Val Ile Leu Phe Met Leu Val Cys
                 200                 205                 210

 Glu Gln Pro Pro Phe Gln Glu Ala Asn Asp Ser Glu Thr Leu Thr
                 215                 220                 225

 Met Ile Met Asp Cys Lys Tyr Thr Val Pro Ser His Val Ser Lys
                 230                 235                 240

 Glu Cys Lys Glu


<210> 1623
<211> 1182
<212> DNA
<213> Homo sapien

<400> 1623
 ttcggcacga gagaactatt aactgccttt cttctgtggg ctgtgatttt 50

 cagaggggaa tgctaaagta tctcctgata tgcagcatga atgaaaatgg 100

 caagtttcct ggccttcctt ctgctcaact ttcgtgtctg cctccttttg 150

 cttcagctgc tcatgcctca ctcagctcag ttttctgtgc ttggaccctc 200

 tgggcccatc ctggccatgg tgggtgaaga cgctgatctg ccctgtcacc 250

 tgttcccgac catgagtgca gagaccatgg agctgaagtg ggtaagttcc 300

 agcctaaggc aggtggtgaa cgtgtatgca gatggaaagg aagtggaaga 350

 caggcagagt gcaccgtatc gagggagaac ttcgattctg cgggatggca 400

 tcactgcagg gaaggctgct ttccgaatac acaacgtcac aggctctgac 450

 aggtggaagt acctgtgtta tttccaagat ggtgacttct atgaaaaagc 500

 cctggtggag ctgaaggttg cagcactggg ttctgatctt cacgttgatg 550

 tgaagggtta caaggatgga gggatccatc tggagtgcag gtccactggc 600

 tggtaccccc aaccccaaat acagtggagc aacaacaagg gagagaacat 650

 cccgactgtg gaagcacctg tggttgcaga cggagtgggc ctgtatgcag 700

 tagcagcatc tgtgatcatg agaggcagct ctggggaggg tgtatcctgt 750

 accatcagaa attccctcct cggcctggaa aagacagcca gcatttccat 800

 cgcaagaccc ttcttcagga gcgcccagag gtggatcgcc gccctggcag 850

 ggaccctgcc tgtcttgctg ctgctccttg ggggagccgg ttacttcctg 900

 tggcaacagc aggaggaaaa aaagactcag ttcagaaaga aaaagagaga 950

 gcaagagttg agagaaatgg catggagcac aatgaagcaa gaacaaagca 1000

 caagagtgaa gctcctggag gaactcagat ggagaagtat ccagtatgca 1050

 tctcggggag agagacattc agcctataat gaatggaaaa aggccctctt 1100

 caagcctggt gaggaaatgc ttcagatgag gctccacttt gttaaataaa 1150

 atggatgaat gaaaaaaaaa aaaaaaaaaa aa 1182

<210> 1624
<211> 350
<212> PRT
<213> Homo sapien

<400> 1624
 Met Ala Ser Phe Leu Ala Phe Leu Leu Leu Asn Phe Arg Val Cys
   1               5                  10                  15

 Leu Leu Leu Leu Gln Leu Leu Met Pro His Ser Ala Gln Phe Ser
                  20                  25                  30

 Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly Glu Asp
                  35                  40                  45

 Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala Glu Thr
                  50                  55                  60

 Met Glu Leu Lys Trp Val Ser Ser Ser Leu Arg Gln Val Val Asn
                  65                  70                  75

 Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser Ala Pro
                  80                  85                  90

 Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr Ala Gly
                  95                 100                 105

 Lys Ala Ala Phe Arg Ile His Asn Val Thr Gly Ser Asp Arg Trp
                 110                 115                 120

 Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu Lys Ala
                 125                 130                 135

 Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asp Leu His Val
                 140                 145                 150

 Asp Val Lys Gly Tyr Lys Asp Gly Gly Ile His Leu Glu Cys Arg
                 155                 160                 165

 Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Gln Trp Ser Asn Asn
                 170                 175                 180

 Lys Gly Glu Asn Ile Pro Thr Val Glu Ala Pro Val Val Ala Asp
                 185                 190                 195

 Gly Val Gly Leu Tyr Ala Val Ala Ala Ser Val Ile Met Arg Gly
                 200                 205                 210

 Ser Ser Gly Glu Gly Val Ser Cys Thr Ile Arg Asn Ser Leu Leu
                 215                 220                 225

 Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Arg Pro Phe Phe
                 230                 235                 240

 Arg Ser Ala Gln Arg Trp Ile Ala Ala Leu Ala Gly Thr Leu Pro
                 245                 250                 255

 Val Leu Leu Leu Leu Leu Gly Gly Ala Gly Tyr Phe Leu Trp Gln
                 260                 265                 270

 Gln Gln Glu Glu Lys Lys Thr Gln Phe Arg Lys Lys Lys Arg Glu
                 275                 280                 285

 Gln Glu Leu Arg Glu Met Ala Trp Ser Thr Met Lys Gln Glu Gln
                 290                 295                 300

 Ser Thr Arg Val Lys Leu Leu Glu Glu Leu Arg Trp Arg Ser Ile
                 305                 310                 315

 Gln Tyr Ala Ser Arg Gly Glu Arg His Ser Ala Tyr Asn Glu Trp
                 320                 325                 330

 Lys Lys Ala Leu Phe Lys Pro Gly Glu Glu Met Leu Gln Met Arg
                 335                 340                 345

 Leu His Phe Val Lys
                 350

<210> 1625
<211> 4857
<212> DNA
<213> Homo sapien

<400> 1625
 ccgccgccac tgccgtcggg taaggtccca gcacggacat ggcctcgcgc 50

 ggcgcccgcc cgggcccgag tcccccgcgc cccgctttgt agccccccgg 100

 cggagaggcg gcctcgacgg tgcggacggc gcagacggcc gggcgggcgg 150

 catggaggcg gcgcatctgc tcccggccgc cgacgtgctg cgccacttct 200

 cggtgacagc cgagggcggc ctgagcccgg cgcaggtgac cggcgcgcgg 250

 gagcgctacg gccccaacga gctcccgagt gaggaaggga agtccctgtg 300

 ggagctggtg ctggaacagt ttgaggacct cctggtgcgc atcctgctgc 350

 tggctgccct tgtctccttt gtcctggcct ggttcgagga gggcgaggag 400

 accacgaccg ccttcgtgga gcccctggtc atcatgctga tcctcgtggc 450

 caacgccatt gtgggcgtgt ggcaggaacg caacgccgag agtgccatcg 500

 aggccctgaa ggagtatgag cctgagatgg gcaaggtgat ccgctcggac 550

 cgcaagggcg tgcagaggat ccgtgcccgg gacatcgtcc caggggacat 600

 tgtagaagtg gcagtggggg acaaagtgcc tgctgacctc cgcctcatcg 650

 agatcaagtc caccacgctg cgagtggacc agtccatcct gacgggtgaa 700

 tctgtgtccg tgaccaagca cacagaggcc atcccagacc ccagagctgt 750

 gaaccaggac aagaagaaca tgctgttttc tggcaccaat atcacatcgg 800

 gcaaagcggt gggtgtggcc gtggccaccg gcctgcacac ggagctgggc 850

 aagatccgga gccagatggc ggcagtcgag cccgagcgga cgccgctgca 900

 gcgcaagctg gacgagtttg gacggcagct gtcccacgcc atctctgtga 950

 tctgcgtggc cgtgtgggtc atcaacatcg gccacttcgc cgacccggcc 1000

 cacggtggct cctggctgcg tggcgctgtc tactacttca agatcgccgt 1050

 ggccctggcg gtggcggcca tccccgaggg cctcccggct gtcatcacta 1100

 catgcctggc actgggcacg cggcgcatgg cacgcaagaa cgccatcgtg 1150

 cgaagcctgc cgtccgtgga gaccctgggc tgcacctcag tcatctgctc 1200

 cgacaagacg ggcacgctca ccaccaatca gatgtctgtc tgccggatgt 1250

 tcgtggtagc cgaggccgat gcgggctcct gccttttgca cgagttcacc 1300

 atctcgggta ccacgtatac ccccgagggc gaagtgcggc agggggatca 1350

 gcctgtgcgc tgcggccagt tcgacgggct ggtggagctg gcgaccatct 1400

 gcgccctgtg caacgactcg gctctggact acaacgaggc caagggtgtg 1450

 tatgagaagg tgggagaggc cacggagaca gctctgactt gcctggtgga 1500

 gaagatgaac gtgttcgaca ccgacctgca ggctctgtcc cgggtggagc 1550

 gagctggcgc ctgtaacacg gtcatcaagc agctgatgcg gaaggagttc 1600

 accctggagt tctcccgaga ccggaaatcc atgtccgtgt actgcacgcc 1650

 cacccgccct caccctactg gccagggcag caagatgttt gtgaaggggg 1700

 ctcctgagag tgtgatcgag cgctgtagct cagtccgcgt ggggagccgc 1750

 acagcacccc tgacccccac ctccagggag cagatcctgg caaagatccg 1800

 ggattggggc tcaggctcag acacgctgcg ctgcctggca ctggccaccc 1850

 gggacgcgcc cccaaggaag gaggacatgg agctggacga ctgcagcaag 1900

 tttgtgcagt acgagacgga cctgaccttc gtgggctgcg taggcatgct 1950

 ggacccgccg cgacctgagg tggctgcctg catcacacgc tgctaccagg 2000

 cgggcatccg cgtggtcatg atcacggggg ataacaaagg cactgccgtg 2050

 gccatctgcc gcaggcttgg catctttggg gacacggaag acgtggcggg 2100

 caaggcctac acgggccgcg agtttgatga cctcagcccc gagcagcagc 2150

 gccaggcctg ccgcaccgcc cgctgcttcg cccgcgtgga gcccgcacac 2200

 aagtcccgca tcgtggagaa cctgcagtcc tttaacgaga tcactgctat 2250

 gactggcgat ggagtgaacg acgcaccagc cctgaagaaa gcagagatcg 2300

 gcatcgccat gggctcaggc acggccgtgg ccaagtcggc ggcagagatg 2350

 gtgctgtcag atgacaactt tgcctccatc gtggctgcgg tggaggaggg 2400

 ccgggccatc tacagcaaca tgaagcaatt catccgctac ctcatctcct 2450

 ccaatgttgg cgaggtcgtc tgcatcttcc tcacggcaat tctgggcctg 2500

 cccgaagccc tgatccctgt gcagctgctc tgggtgaacc tggtgacaga 2550

 cggcctacct gccacggctc tgggcttcaa cccgccagac ctggacatca 2600

 tggagaagct gccccggagc ccccgagaag ccctcatcag tggctggctc 2650

 ttcttccgat acctggctat cggagtgtac gtaggcctgg ccacagtggc 2700

 tgccgccacc tggtggtttg tgtatgacgc cgagggacct cacatcaact 2750

 tctaccagct gaggaacttc ctgaagtgct ccgaagacaa cccgctcttt 2800

 gccggcatcg actgtgaggt gttcgagtca cgcttcccca ccaccatggc 2850

 cttgtccgtg ctcgtgacca ttgaaatgtg caatgccctc aacagcgtct 2900

 cggagaacca gtcgctgctg cggatgccgc cctggatgaa cccctggctg 2950

 ctggtggctg tggccatgtc catggccctg cacttcctca tcctgctcgt 3000

 gccgcccctg cctctcattt tccaggtgac cccactgagc gggcgccagt 3050

 gggtggtggt gctccagata tctctgcctg tcatcctgct ggatgaggcc 3100

 ctcaagtacc tgtcccggaa ccacatgcac gcctgtcttt atccaggcct 3150

 tctcaggaca gtctcgcagg cctggagtag gcagccgctg accacctctt 3200

 ggaccccaga ccacaccggg ttggcctctt tgggccaggg acacagcatc 3250

 gtctcgctgt cagagctgct cagagaggga ggaagcaggg aagaaatgag 3300

 ccagaagtga gcgctgggaa cagagtggag tctccggtgt gtacctcaga 3350

 ctgatggtgc ccatgtgttc gcctccgccc cccacccttg ccaccacact 3400

 cgcccacttg cccaccgggt cccgccggat aaatgacagg cccgaggtca 3450

 gaatggccat ccccgggccc cgtcctgggg tctctgtccc cacttccttc 3500

 tggcctggga ggtctgtaat tcctgtctcc tggactctcc tgggaagttc 3550

 cctgctctgc agctctggcc caggagctgc aggctgggag ggggcagcca 3600

 agaagccgga gctggcagca tacccagaga tccggggccc ccccaccccc 3650

 aaatcacgag tgcagctgga gcttgctccc ccttgttcgg aagctggacg 3700

 ttcacttggt gactggtgcc tctgcactga cggaggactc tgggggtcct 3750

 tcttaccggc tctgacctct ctcttcgtgc ctggtctggg actgggtcag 3800

 ccctggggga tcagaagggg ccatctgggc ccagctgtgt acagcgaggg 3850

 tgggcagccc cctccactcc actctgcttc cacaaagtcg gctcccgaga 3900

 gctcgaggct gcttctgttt atatgtgcag ggcccgggcg ggtgaagggt 3950

 cagagagacg gacacaagga gccggcagga gggcggagcg aggatgtcct 4000

 ttcccgggag acaagtcggg aaagcctggc tggactgcct cagccccgcg 4050

 cgcctcctgg actcagggtt ccccgtcctg agctcgggag atgttcagag 4100

 tcacactgcc gcccggtctg ccacgcagag gtccaacttg ccacccgcgt 4150

 ccctggtacc tgagaccacc gacatcctca ggttcctgac cgtggcgccc 4200

 ttctacccag cccagtgtgc ggccgccgcg ctgtctgcac agctgggggc 4250

 ctctgagcct ggtgggcttc ctggactctt ggcctcactc cttgccccct 4300

 ccccacgaca cccatgagcc gaaaggatgt cactaaggat ggctgattcc 4350

 ccaagggcac ccgctctccc tccctccctg ctggaggaac acgtcatatc 4400

 agatgagagg aagatggcct ctgatggaca gaatttttct cttaactcag 4450

 cttttgctac tttggcaaaa actagcgagg ggtagcagaa acctgcacca 4500

 aggattgtcc ctatgtcttg gccactccta gagcgtgtgc agactgatga 4550

 ttttatatgt aaatcaagac tcacatccct ttcctagtcc cccacatcca 4600

 aagcccctca gcctgccttg cagaccaatg ggctccatgt tctgtagccc 4650

 cctcccctac gcctcacccc tcctccctct cacaggttct gggcggccag 4700

 tgagagaaac gcagtggggg aggcagggag tctggtgcct gcagagattc 4750

 tctgcttctt tcctgggggg aggtggggag gtcttagcag gagcgggccc 4800

 tgtacccacc tgctgacctg ctgtttggta gagaaataaa ggttgtgtga 4850

 ctggggg 4857

<210> 1626
<211> 1052
<212> PRT
<213> Homo sapien

<400> 1626
 Met Glu Ala Ala His Leu Leu Pro Ala Ala Asp Val Leu Arg His
   1               5                  10                  15

 Phe Ser Val Thr Ala Glu Gly Gly Leu Ser Pro Ala Gln Val Thr
                  20                  25                  30

 Gly Ala Arg Glu Arg Tyr Gly Pro Asn Glu Leu Pro Ser Glu Glu
                  35                  40                  45

 Gly Lys Ser Leu Trp Glu Leu Val Leu Glu Gln Phe Glu Asp Leu
                  50                  55                  60

 Leu Val Arg Ile Leu Leu Leu Ala Ala Leu Val Ser Phe Val Leu
                  65                  70                  75

 Ala Trp Phe Glu Glu Gly Glu Glu Thr Thr Thr Ala Phe Val Glu
                  80                  85                  90

 Pro Leu Val Ile Met Leu Ile Leu Val Ala Asn Ala Ile Val Gly
                  95                 100                 105

 Val Trp Gln Glu Arg Asn Ala Glu Ser Ala Ile Glu Ala Leu Lys
                 110                 115                 120

 Glu Tyr Glu Pro Glu Met Gly Lys Val Ile Arg Ser Asp Arg Lys
                 125                 130                 135

 Gly Val Gln Arg Ile Arg Ala Arg Asp Ile Val Pro Gly Asp Ile
                 140                 145                 150

 Val Glu Val Ala Val Gly Asp Lys Val Pro Ala Asp Leu Arg Leu
                 155                 160                 165

 Ile Glu Ile Lys Ser Thr Thr Leu Arg Val Asp Gln Ser Ile Leu
                 170                 175                 180

 Thr Gly Glu Ser Val Ser Val Thr Lys His Thr Glu Ala Ile Pro
                 185                 190                 195

 Asp Pro Arg Ala Val Asn Gln Asp Lys Lys Asn Met Leu Phe Ser
                 200                 205                 210

 Gly Thr Asn Ile Thr Ser Gly Lys Ala Val Gly Val Ala Val Ala
                 215                 220                 225

 Thr Gly Leu His Thr Glu Leu Gly Lys Ile Arg Ser Gln Met Ala
                 230                 235                 240

 Ala Val Glu Pro Glu Arg Thr Pro Leu Gln Arg Lys Leu Asp Glu
                 245                 250                 255

 Phe Gly Arg Gln Leu Ser His Ala Ile Ser Val Ile Cys Val Ala
                 260                 265                 270

 Val Trp Val Ile Asn Ile Gly His Phe Ala Asp Pro Ala His Gly
                 275                 280                 285

 Gly Ser Trp Leu Arg Gly Ala Val Tyr Tyr Phe Lys Ile Ala Val
                 290                 295                 300

 Ala Leu Ala Val Ala Ala Ile Pro Glu Gly Leu Pro Ala Val Ile
                 305                 310                 315

 Thr Thr Cys Leu Ala Leu Gly Thr Arg Arg Met Ala Arg Lys Asn
                 320                 325                 330

 Ala Ile Val Arg Ser Leu Pro Ser Val Glu Thr Leu Gly Cys Thr
                 335                 340                 345

 Ser Val Ile Cys Ser Asp Lys Thr Gly Thr Leu Thr Thr Asn Gln
                 350                 355                 360

 Met Ser Val Cys Arg Met Phe Val Val Ala Glu Ala Asp Ala Gly
                 365                 370                 375

 Ser Cys Leu Leu His Glu Phe Thr Ile Ser Gly Thr Thr Tyr Thr
                 380                 385                 390

 Pro Glu Gly Glu Val Arg Gln Gly Asp Gln Pro Val Arg Cys Gly
                 395                 400                 405

 Gln Phe Asp Gly Leu Val Glu Leu Ala Thr Ile Cys Ala Leu Cys
                 410                 415                 420

 Asn Asp Ser Ala Leu Asp Tyr Asn Glu Ala Lys Gly Val Tyr Glu
                 425                 430                 435

 Lys Val Gly Glu Ala Thr Glu Thr Ala Leu Thr Cys Leu Val Glu
                 440                 445                 450

 Lys Met Asn Val Phe Asp Thr Asp Leu Gln Ala Leu Ser Arg Val
                 455                 460                 465

 Glu Arg Ala Gly Ala Cys Asn Thr Val Ile Lys Gln Leu Met Arg
                 470                 475                 480

 Lys Glu Phe Thr Leu Glu Phe Ser Arg Asp Arg Lys Ser Met Ser
                 485                 490                 495

 Val Tyr Cys Thr Pro Thr Arg Pro His Pro Thr Gly Gln Gly Ser
                 500                 505                 510

 Lys Met Phe Val Lys Gly Ala Pro Glu Ser Val Ile Glu Arg Cys
                 515                 520                 525

 Ser Ser Val Arg Val Gly Ser Arg Thr Ala Pro Leu Thr Pro Thr
                 530                 535                 540

 Ser Arg Glu Gln Ile Leu Ala Lys Ile Arg Asp Trp Gly Ser Gly
                 545                 550                 555

 Ser Asp Thr Leu Arg Cys Leu Ala Leu Ala Thr Arg Asp Ala Pro
                 560                 565                 570

 Pro Arg Lys Glu Asp Met Glu Leu Asp Asp Cys Ser Lys Phe Val
                 575                 580                 585

 Gln Tyr Glu Thr Asp Leu Thr Phe Val Gly Cys Val Gly Met Leu
                 590                 595                 600

 Asp Pro Pro Arg Pro Glu Val Ala Ala Cys Ile Thr Arg Cys Tyr
                 605                 610                 615

 Gln Ala Gly Ile Arg Val Val Met Ile Thr Gly Asp Asn Lys Gly
                 620                 625                 630

 Thr Ala Val Ala Ile Cys Arg Arg Leu Gly Ile Phe Gly Asp Thr
                 635                 640                 645

 Glu Asp Val Ala Gly Lys Ala Tyr Thr Gly Arg Glu Phe Asp Asp
                 650                 655                 660

 Leu Ser Pro Glu Gln Gln Arg Gln Ala Cys Arg Thr Ala Arg Cys
                 665                 670                 675

 Phe Ala Arg Val Glu Pro Ala His Lys Ser Arg Ile Val Glu Asn
                 680                 685                 690

 Leu Gln Ser Phe Asn Glu Ile Thr Ala Met Thr Gly Asp Gly Val
                 695                 700                 705

 Asn Asp Ala Pro Ala Leu Lys Lys Ala Glu Ile Gly Ile Ala Met
                 710                 715                 720

 Gly Ser Gly Thr Ala Val Ala Lys Ser Ala Ala Glu Met Val Leu
                 725                 730                 735

 Ser Asp Asp Asn Phe Ala Ser Ile Val Ala Ala Val Glu Glu Gly
                 740                 745                 750

 Arg Ala Ile Tyr Ser Asn Met Lys Gln Phe Ile Arg Tyr Leu Ile
                 755                 760                 765

 Ser Ser Asn Val Gly Glu Val Val Cys Ile Phe Leu Thr Ala Ile
                 770                 775                 780

 Leu Gly Leu Pro Glu Ala Leu Ile Pro Val Gln Leu Leu Trp Val
                 785                 790                 795

 Asn Leu Val Thr Asp Gly Leu Pro Ala Thr Ala Leu Gly Phe Asn
                 800                 805                 810

 Pro Pro Asp Leu Asp Ile Met Glu Lys Leu Pro Arg Ser Pro Arg
                 815                 820                 825

 Glu Ala Leu Ile Ser Gly Trp Leu Phe Phe Arg Tyr Leu Ala Ile
                 830                 835                 840

 Gly Val Tyr Val Gly Leu Ala Thr Val Ala Ala Ala Thr Trp Trp
                 845                 850                 855

 Phe Val Tyr Asp Ala Glu Gly Pro His Ile Asn Phe Tyr Gln Leu
                 860                 865                 870

 Arg Asn Phe Leu Lys Cys Ser Glu Asp Asn Pro Leu Phe Ala Gly
                 875                 880                 885

 Ile Asp Cys Glu Val Phe Glu Ser Arg Phe Pro Thr Thr Met Ala
                 890                 895                 900

 Leu Ser Val Leu Val Thr Ile Glu Met Cys Asn Ala Leu Asn Ser
                 905                 910                 915

 Val Ser Glu Asn Gln Ser Leu Leu Arg Met Pro Pro Trp Met Asn
                 920                 925                 930

 Pro Trp Leu Leu Val Ala Val Ala Met Ser Met Ala Leu His Phe
                 935                 940                 945

 Leu Ile Leu Leu Val Pro Pro Leu Pro Leu Ile Phe Gln Val Thr
                 950                 955                 960

 Pro Leu Ser Gly Arg Gln Trp Val Val Val Leu Gln Ile Ser Leu
                 965                 970                 975

 Pro Val Ile Leu Leu Asp Glu Ala Leu Lys Tyr Leu Ser Arg Asn
                 980                 985                 990

 His Met His Ala Cys Leu Tyr Pro Gly Leu Leu Arg Thr Val Ser
                 995                1000                1005

 Gln Ala Trp Ser Arg Gln Pro Leu Thr Thr Ser Trp Thr Pro Asp
                1010                1015                1020

 His Thr Gly Leu Ala Ser Leu Gly Gln Gly His Ser Ile Val Ser
                1025                1030                1035

 Leu Ser Glu Leu Leu Arg Glu Gly Gly Ser Arg Glu Glu Met Ser
                1040                1045                1050

 Gln Lys


<210> 1627
<211> 4844
<212> DNA
<213> Homo sapien

<400> 1627
 ccgccgccac tgccgtcggg taaggtccca gcacggacat ggcctcgcgc 50

 ggcgcccgcc cgggcccgag tcccccgcgc cccgctttgt agccccccgg 100

 cggagaggcg gcctcgacgg tgcggacggc gcagacggcc gggcgggcgg 150

 catggaggcg gcgcatctgc tcccggccgc cgacgtgctg cgccacttct 200

 cggtgacagc cgagggcggc ctgagcccgg cgcaggtgac cggcgcgcgg 250

 gagcgctacg gccccaacga gctcccgagt gaggaaggga agtccctgtg 300

 ggagctggtg ctggaacagt ttgaggacct cctggtgcgc atcctgctgc 350

 tggctgccct tgtctccttt gtcctggcct ggttcgagga gggcgaggag 400

 accacgaccg ccttcgtgga gcccctggtc atcatgctga tcctcgtggc 450

 caacgccatt gtgggcgtgt ggcaggaacg caacgccgag agtgccatcg 500

 aggccctgaa ggagtatgag cctgagatgg gcaaggtgat ccgctcggac 550

 cgcaagggcg tgcagaggat ccgtgcccgg gacatcgtcc caggggacat 600

 tgtagaagtg gcagtggggg acaaagtgcc tgctgacctc cgcctcatcg 650

 agatcaagtc caccacgctg cgagtggacc agtccatcct gacgggtgaa 700

 tctgtgtccg tgaccaagca cacagaggcc atcccagacc ccagagctgt 750

 gaaccaggac aagaagaaca tgctgttttc tggcaccaat atcacatcgg 800

 gcaaagcggt gggtgtggcc gtggccaccg gcctgcacac ggagctgggc 850

 aagatccgga gccagatggc ggcagtcgag cccgagcgga cgccgctgca 900

 gcgcaagctg gacgagtttg gacggcagct gtcccacgcc atctctgtga 950

 tctgcgtggc cgtgtgggtc atcaacatcg gccacttcgc cgacccggcc 1000

 cacggtggct cctggctgcg tggcgctgtc tactacttca agatcgccgt 1050

 ggccctggcg gtggcggcca tccccgaggg cctcccggct gtcatcacta 1100

 catgcctggc actgggcacg cggcgcatgg cacgcaagaa cgccatcgtg 1150

 cgaagcctgc cgtccgtgga gaccctgggc tgcacctcag tcatctgctc 1200

 cgacaagacg ggcacgctca ccaccaatca gatgtctgtc tgccggatgt 1250

 tcgtggtagc cgaggccgat gcgggctcct gccttttgca cgagttcacc 1300

 atctcgggta ccacgtatac ccccgagggc gaagtgcggc agggggatca 1350

 gcctgtgcgc tgcggccagt tcgacgggct ggtggagctg gcgaccatct 1400

 gcgccctgtg caacgactcg gctctggact acaacgaggc caagggtgtg 1450

 tatgagaagg tgggagaggc cacggagaca gctctgactt gcctggtgga 1500

 gaagatgaac gtgttcgaca ccgacctgca ggctctgtcc cgggtggagc 1550

 gagctggcgc ctgtaacacg gtcatcaagc agctgatgcg gaaggagttc 1600

 accctggagt tctcccgaga ccggaaatcc atgtccgtgt actgcacgcc 1650

 cacccgccct caccctactg gccagggcag caagatgttt gtgaaggggg 1700

 ctcctgagag tgtgatcgag cgctgtagct cagtccgcgt ggggagccgc 1750

 acagcacccc tgacccccac ctccagggag cagatcctgg caaagatccg 1800

 ggattggggc tcaggctcag acacgctgcg ctgcctggca ctggccaccc 1850

 gggacgcgcc cccaaggaag gaggacatgg agctggacga ctgcagcaag 1900

 tttgtgcagt acgagacgga cctgaccttc gtgggctgcg taggcatgct 1950

 ggacccgccg cgacctgagg tggctgcctg catcacacgc tgctaccagg 2000

 cgggcatccg cgtggtcatg atcacggggg ataacaaagg cactgccgtg 2050

 gccatctgcc gcaggcttgg catctttggg gacacggaag acgtggcggg 2100

 caaggcctac acgggccgcg agtttgatga cctcagcccc gagcagcagc 2150

 gccaggcctg ccgcaccgcc cgctgcttcg cccgcgtgga gcccgcacac 2200

 aagtcccgca tcgtggagaa cctgcagtcc tttaacgaga tcactgctat 2250

 gactggcgat ggagtgaacg acgcaccagc cctgaagaaa gcagagatcg 2300

 gcatcgccat gggctcaggc acggccgtgg ccaagtcggc ggcagagatg 2350

 gtgctgtcag atgacaactt tgcctccatc gtggctgcgg tggaggaggg 2400

 ccgggccatc tacagcaaca tgaagcaatt catccgctac ctcatctcct 2450

 ccaatgttgg cgaggtcgtc tgcatcttcc tcacggcaat tctgggcctg 2500

 cccgaagccc tgatccctgt gcagctgctc tgggtgaacc tggtgacaga 2550

 cggcctacct gccacggctc tgggcttcaa cccgccagac ctggacatca 2600

 tggagaagct gccccggagc ccccgagaag ccctcatcag tggctggctc 2650

 ttcttccgat acctggctat cggagtgtac gtaggcctgg ccacagtggc 2700

 tgccgccacc tggtggtttg tgtatgacgc cgagggacct cacatcaact 2750

 tctaccagct gaggaacttc ctgaagtgct ccgaagacaa cccgctcttt 2800

 gccggcatcg actgtgaggt gttcgagtca cgcttcccca ccaccatggc 2850

 cttgtccgtg ctcgtgacca ttgaaatgtg caatgccctc aacagcgtct 2900

 cggagaacca gtcgctgctg cggatgccgc cctggatgaa cccctggctg 2950

 ctggtggctg tggccatgtc catggccctg cacttcctca tcctgctcgt 3000

 gccgcccctg cctctcattt tccaggtgac cccactgagc gggcgccagt 3050

 gggtggtggt gctccagata tctctgcctg tcatcctgct ggatgaggcc 3100

 ctcaagtacc tgtcccggaa ccacatgcac gcctgtcttt atccaggcct 3150

 tctcaggaca gtctcgcagg cctggagtag gcagccgctg accacctctt 3200

 ggaccccaga ccacaccggg gccagggaca cagcatcgtc tcgctgtcag 3250

 agctgctcag agagggagga agcagggaag aaatgagcca gaagtgagcg 3300

 ctgggaacag agtggagtct ccggtgtgta cctcagactg atggtgccca 3350

 tgtgttcgcc tccgcccccc acccttgcca ccacactcgc ccacttgccc 3400

 accgggtccc gccggataaa tgacaggccc gaggtcagaa tggccatccc 3450

 cgggccccgt cctggggtct ctgtccccac ttccttctgg cctgggaggt 3500

 ctgtaattcc tgtctcctgg actctcctgg gaagttccct gctctgcagc 3550

 tctggcccag gagctgcagg ctgggagggg gcagccaaga agccggagct 3600

 ggcagcatac ccagagatcc ggggcccccc cacccccaaa tcacgagtgc 3650

 agctggagct tgctccccct tgttcggaag ctggacgttc acttggtgac 3700

 tggtgcctct gcactgacgg aggactctgg gggtccttct taccggctct 3750

 gacctctctc ttcgtgcctg gtctgggact gggtcagccc tgggggatca 3800

 gaaggggcca tctgggccca gctgtgtaca gcgagggtgg gcagccccct 3850

 ccactccact ctgcttccac aaagtcggct cccgagagct cgaggctgct 3900

 tctgtttata tgtgcagggc ccgggcgggt gaagggtcag agagacggac 3950

 acaaggagcc ggcaggaggg cggagcgagg atgtcctttc ccgggagaca 4000

 agtcgggaaa gcctggctgg actgcctcag ccccgcgcgc ctcctggact 4050

 cagggttccc cgtcctgagc tcgggagatg ttcagagtca cactgccgcc 4100

 cggtctgcca cgcagaggtc caacttgcca cccgcgtccc tggtacctga 4150

 gaccaccgac atcctcaggt tcctgaccgt ggcgcccttc tacccagccc 4200

 agtgtgcggc cgccgcgctg tctgcacagc tgggggcctc tgagcctggt 4250

 gggcttcctg gactcttggc ctcactcctt gccccctccc cacgacaccc 4300

 atgagccgaa aggatgtcac taaggatggc tgattcccca agggcacccg 4350

 ctctccctcc ctccctgctg gaggaacacg tcatatcaga tgagaggaag 4400

 atggcctctg atggacagaa tttttctctt aactcagctt ttgctacttt 4450

 ggcaaaaact agcgaggggt agcagaaacc tgcaccaagg attgtcccta 4500

 tgtcttggcc actcctagag cgtgtgcaga ctgatgattt tatatgtaaa 4550

 tcaagactca catccctttc ctagtccccc acatccaaag cccctcagcc 4600

 tgccttgcag accaatgggc tccatgttct gtagccccct cccctacgcc 4650

 tcacccctcc tccctctcac aggttctggg cggccagtga gagaaacgca 4700

 gtgggggagg cagggagtct ggtgcctgca gagattctct gcttctttcc 4750

 tggggggagg tggggaggtc ttagcaggag cgggccctgt acccacctgc 4800

 tgacctgctg tttggtagag aaataaaggt tgtgtgactg gggg 4844

<210> 1628
<211> 1044
<212> PRT
<213> Homo sapien

<400> 1628
 Met Glu Ala Ala His Leu Leu Pro Ala Ala Asp Val Leu Arg His
   1               5                  10                  15

 Phe Ser Val Thr Ala Glu Gly Gly Leu Ser Pro Ala Gln Val Thr
                  20                  25                  30

 Gly Ala Arg Glu Arg Tyr Gly Pro Asn Glu Leu Pro Ser Glu Glu
                  35                  40                  45

 Gly Lys Ser Leu Trp Glu Leu Val Leu Glu Gln Phe Glu Asp Leu
                  50                  55                  60

 Leu Val Arg Ile Leu Leu Leu Ala Ala Leu Val Ser Phe Val Leu
                  65                  70                  75

 Ala Trp Phe Glu Glu Gly Glu Glu Thr Thr Thr Ala Phe Val Glu
                  80                  85                  90

 Pro Leu Val Ile Met Leu Ile Leu Val Ala Asn Ala Ile Val Gly
                  95                 100                 105

 Val Trp Gln Glu Arg Asn Ala Glu Ser Ala Ile Glu Ala Leu Lys
                 110                 115                 120

 Glu Tyr Glu Pro Glu Met Gly Lys Val Ile Arg Ser Asp Arg Lys
                 125                 130                 135

 Gly Val Gln Arg Ile Arg Ala Arg Asp Ile Val Pro Gly Asp Ile
                 140                 145                 150

 Val Glu Val Ala Val Gly Asp Lys Val Pro Ala Asp Leu Arg Leu
                 155                 160                 165

 Ile Glu Ile Lys Ser Thr Thr Leu Arg Val Asp Gln Ser Ile Leu
                 170                 175                 180

 Thr Gly Glu Ser Val Ser Val Thr Lys His Thr Glu Ala Ile Pro
                 185                 190                 195

 Asp Pro Arg Ala Val Asn Gln Asp Lys Lys Asn Met Leu Phe Ser
                 200                 205                 210

 Gly Thr Asn Ile Thr Ser Gly Lys Ala Val Gly Val Ala Val Ala
                 215                 220                 225

 Thr Gly Leu His Thr Glu Leu Gly Lys Ile Arg Ser Gln Met Ala
                 230                 235                 240

 Ala Val Glu Pro Glu Arg Thr Pro Leu Gln Arg Lys Leu Asp Glu
                 245                 250                 255

 Phe Gly Arg Gln Leu Ser His Ala Ile Ser Val Ile Cys Val Ala
                 260                 265                 270

 Val Trp Val Ile Asn Ile Gly His Phe Ala Asp Pro Ala His Gly
                 275                 280                 285

 Gly Ser Trp Leu Arg Gly Ala Val Tyr Tyr Phe Lys Ile Ala Val
                 290                 295                 300

 Ala Leu Ala Val Ala Ala Ile Pro Glu Gly Leu Pro Ala Val Ile
                 305                 310                 315

 Thr Thr Cys Leu Ala Leu Gly Thr Arg Arg Met Ala Arg Lys Asn
                 320                 325                 330

 Ala Ile Val Arg Ser Leu Pro Ser Val Glu Thr Leu Gly Cys Thr
                 335                 340                 345

 Ser Val Ile Cys Ser Asp Lys Thr Gly Thr Leu Thr Thr Asn Gln
                 350                 355                 360

 Met Ser Val Cys Arg Met Phe Val Val Ala Glu Ala Asp Ala Gly
                 365                 370                 375

 Ser Cys Leu Leu His Glu Phe Thr Ile Ser Gly Thr Thr Tyr Thr
                 380                 385                 390

 Pro Glu Gly Glu Val Arg Gln Gly Asp Gln Pro Val Arg Cys Gly
                 395                 400                 405

 Gln Phe Asp Gly Leu Val Glu Leu Ala Thr Ile Cys Ala Leu Cys
                 410                 415                 420

 Asn Asp Ser Ala Leu Asp Tyr Asn Glu Ala Lys Gly Val Tyr Glu
                 425                 430                 435

 Lys Val Gly Glu Ala Thr Glu Thr Ala Leu Thr Cys Leu Val Glu
                 440                 445                 450

 Lys Met Asn Val Phe Asp Thr Asp Leu Gln Ala Leu Ser Arg Val
                 455                 460                 465

 Glu Arg Ala Gly Ala Cys Asn Thr Val Ile Lys Gln Leu Met Arg
                 470                 475                 480

 Lys Glu Phe Thr Leu Glu Phe Ser Arg Asp Arg Lys Ser Met Ser
                 485                 490                 495

 Val Tyr Cys Thr Pro Thr Arg Pro His Pro Thr Gly Gln Gly Ser
                 500                 505                 510

 Lys Met Phe Val Lys Gly Ala Pro Glu Ser Val Ile Glu Arg Cys
                 515                 520                 525

 Ser Ser Val Arg Val Gly Ser Arg Thr Ala Pro Leu Thr Pro Thr
                 530                 535                 540

 Ser Arg Glu Gln Ile Leu Ala Lys Ile Arg Asp Trp Gly Ser Gly
                 545                 550                 555

 Ser Asp Thr Leu Arg Cys Leu Ala Leu Ala Thr Arg Asp Ala Pro
                 560                 565                 570

 Pro Arg Lys Glu Asp Met Glu Leu Asp Asp Cys Ser Lys Phe Val
                 575                 580                 585

 Gln Tyr Glu Thr Asp Leu Thr Phe Val Gly Cys Val Gly Met Leu
                 590                 595                 600

 Asp Pro Pro Arg Pro Glu Val Ala Ala Cys Ile Thr Arg Cys Tyr
                 605                 610                 615

 Gln Ala Gly Ile Arg Val Val Met Ile Thr Gly Asp Asn Lys Gly
                 620                 625                 630

 Thr Ala Val Ala Ile Cys Arg Arg Leu Gly Ile Phe Gly Asp Thr
                 635                 640                 645

 Glu Asp Val Ala Gly Lys Ala Tyr Thr Gly Arg Glu Phe Asp Asp
                 650                 655                 660

 Leu Ser Pro Glu Gln Gln Arg Gln Ala Cys Arg Thr Ala Arg Cys
                 665                 670                 675

 Phe Ala Arg Val Glu Pro Ala His Lys Ser Arg Ile Val Glu Asn
                 680                 685                 690

 Leu Gln Ser Phe Asn Glu Ile Thr Ala Met Thr Gly Asp Gly Val
                 695                 700                 705

 Asn Asp Ala Pro Ala Leu Lys Lys Ala Glu Ile Gly Ile Ala Met
                 710                 715                 720

 Gly Ser Gly Thr Ala Val Ala Lys Ser Ala Ala Glu Met Val Leu
                 725                 730                 735

 Ser Asp Asp Asn Phe Ala Ser Ile Val Ala Ala Val Glu Glu Gly
                 740                 745                 750

 Arg Ala Ile Tyr Ser Asn Met Lys Gln Phe Ile Arg Tyr Leu Ile
                 755                 760                 765

 Ser Ser Asn Val Gly Glu Val Val Cys Ile Phe Leu Thr Ala Ile
                 770                 775                 780

 Leu Gly Leu Pro Glu Ala Leu Ile Pro Val Gln Leu Leu Trp Val
                 785                 790                 795

 Asn Leu Val Thr Asp Gly Leu Pro Ala Thr Ala Leu Gly Phe Asn
                 800                 805                 810

 Pro Pro Asp Leu Asp Ile Met Glu Lys Leu Pro Arg Ser Pro Arg
                 815                 820                 825

 Glu Ala Leu Ile Ser Gly Trp Leu Phe Phe Arg Tyr Leu Ala Ile
                 830                 835                 840

 Gly Val Tyr Val Gly Leu Ala Thr Val Ala Ala Ala Thr Trp Trp
                 845                 850                 855

 Phe Val Tyr Asp Ala Glu Gly Pro His Ile Asn Phe Tyr Gln Leu
                 860                 865                 870

 Arg Asn Phe Leu Lys Cys Ser Glu Asp Asn Pro Leu Phe Ala Gly
                 875                 880                 885

 Ile Asp Cys Glu Val Phe Glu Ser Arg Phe Pro Thr Thr Met Ala
                 890                 895                 900

 Leu Ser Val Leu Val Thr Ile Glu Met Cys Asn Ala Leu Asn Ser
                 905                 910                 915

 Val Ser Glu Asn Gln Ser Leu Leu Arg Met Pro Pro Trp Met Asn
                 920                 925                 930

 Pro Trp Leu Leu Val Ala Val Ala Met Ser Met Ala Leu His Phe
                 935                 940                 945

 Leu Ile Leu Leu Val Pro Pro Leu Pro Leu Ile Phe Gln Val Thr
                 950                 955                 960

 Pro Leu Ser Gly Arg Gln Trp Val Val Val Leu Gln Ile Ser Leu
                 965                 970                 975

 Pro Val Ile Leu Leu Asp Glu Ala Leu Lys Tyr Leu Ser Arg Asn
                 980                 985                 990

 His Met His Ala Cys Leu Tyr Pro Gly Leu Leu Arg Thr Val Ser
                 995                1000                1005

 Gln Ala Trp Ser Arg Gln Pro Leu Thr Thr Ser Trp Thr Pro Asp
                1010                1015                1020

 His Thr Gly Ala Arg Asp Thr Ala Ser Ser Arg Cys Gln Ser Cys
                1025                1030                1035

 Ser Glu Arg Glu Glu Ala Gly Lys Lys
                1040

<210> 1629
<211> 542
<212> DNA
<213> Homo sapien

<400> 1629
 acagtggtga gctcttagct tcaccaggct catcaaagct gctccaggaa 50

 ggcccaagcc agaccagaag acatgcagat catcaccaca gccctggtgt 100

 gcttgctgct agctgggatg tggccggaag atgtggacag caagagcatg 150

 caggtaccct tctccagatg ttgcttctca tttgcggagc aagagattcc 200

 cctgagggca atcctgtgtt acagaaatac cagctccatc tgctccaatg 250

 agggcttaat attcaagctg aagagaggca aagaggcctg cgccttggac 300

 acagttggat gggttcagag gcacagaaaa atgctgaggc actgcccgtc 350

 aaaaagaaaa tgagcagatt tctttccatt gtgggctctg gaaaccacat 400

 ggcttcacct gtccccgaaa ctaccagccc tacaccattc cttctgccct 450

 gcttttgcta ggtcacagag gatctgcttg gtcttgataa gctatgttgt 500

 tgcactttaa acatttaaat tatacaatca tcaaccccca ac 542

<210> 1630
<211> 96
<212> PRT
<213> Homo sapien

<400> 1630
 Met Gln Ile Ile Thr Thr Ala Leu Val Cys Leu Leu Leu Ala Gly
   1               5                  10                  15

 Met Trp Pro Glu Asp Val Asp Ser Lys Ser Met Gln Val Pro Phe
                  20                  25                  30

 Ser Arg Cys Cys Phe Ser Phe Ala Glu Gln Glu Ile Pro Leu Arg
                  35                  40                  45

 Ala Ile Leu Cys Tyr Arg Asn Thr Ser Ser Ile Cys Ser Asn Glu
                  50                  55                  60

 Gly Leu Ile Phe Lys Leu Lys Arg Gly Lys Glu Ala Cys Ala Leu
                  65                  70                  75

 Asp Thr Val Gly Trp Val Gln Arg His Arg Lys Met Leu Arg His
                  80                  85                  90

 Cys Pro Ser Lys Arg Lys
                  95

<210> 1631
<211> 1935
<212> DNA
<213> Homo sapien

<400> 1631
 agaccaagga gtggaaagtt ctccggcagc cctgagatct caagagtgac 50

 atttgtgaga ccagctaatt tgattaaaat tctcttggaa tcagctttgc 100

 tagtatcata cctgtgccag atttcatcat gggaaacagc tgttacaaca 150

 tagtagccac tctgttgctg gtcctcaact ttgagaggac aagatcattg 200

 caggatcctt gtagtaactg cccagctggt acattctgtg ataataacag 250

 gaatcagatt tgcagtccct gtcctccaaa tagtttctcc agcgcaggtg 300

 gacaaaggac ctgtgacata tgcaggcagt gtaaaggtgt tttcaggacc 350

 aggaaggagt gttcctccac cagcaatgca gagtgtgact gcactccagg 400

 gtttcactgc ctgggggcag gatgcagcat gtgtgaacag gattgtaaac 450

 aaggtcaaga actgacaaaa aaaggttgta aagactgttg ctttgggaca 500

 tttaacgatc agaaacgtgg catctgtcga ccctggacaa actgttcttt 550

 ggatggaaag tctgtgcttg tgaatgggac gaaggagagg gacgtggtct 600

 gtggaccatc tccagccgac ctctctccgg gagcatcctc tgtgaccccg 650

 cctgcccctg cgagagagcc aggacactct ccgcagatca tctccttctt 700

 tcttgcgctg acgtcgactg cgttgctctt cctgctgttc ttcctcacgc 750

 tccgtttctc tgttgttaaa cggggcagaa agaaactcct gtatatattc 800

 aaacaaccat ttatgagacc agtacaaact actcaagagg aagatggctg 850

 tagctgccga tttccagaag aagaagaagg aggatgtgaa ctgtgaaatg 900

 gaagtcaata gggctgttgg gactttcttg aaaagaagca aggaaatatg 950

 agtcatccgc tatcacagct ttcaaaagca agaacaccat cctacataat 1000

 acccaggatt cccccaacac acgttctttt ctaaatgcca atgagttggc 1050

 ctttaaaaat gcaccacttt tttttttttt ttgacagggt ctcactctgt 1100

 cacccaggct ggagtgcagt ggcaccacca tggctctctg cagccttgac 1150

 ctctgggagc tcaagtgatc ctcctgcctc agtctcctga gtagctggaa 1200

 ctacaaggaa gggccaccac acctgactaa cttttttgtt ttttgtttgg 1250

 taaagatggc atttcaccat gttgtacagg ctggtctcaa actcctaggt 1300

 tcactttggc ctcccaaagt gctgggatta cagacatgaa ctgccaggcc 1350

 cggccaaaat aatgcaccac ttttaacaga acagacagat gaggacagag 1400

 ctggtgataa aaaaaaaaaa aaaaaagcat tttctagata ccacttaaca 1450

 ggtttgagct agtttttttg aaatccaaag aaaattatag tttaaattca 1500

 attacatagt ccagtggtcc aactataatt ataatcaaaa tcaatgcagg 1550

 tttgtttttt ggtgctaata tgacatatga caataagcca cgaggtgcag 1600

 taagtacccg actaaagttt ccgtgggttc tgtcatgtaa cacgacatgc 1650

 tccaccgtca ggggggagta tgagcagagt gcctgagttt agggtcaagg 1700

 acaaaaaacc tcaggcctgg aggaagtttt ggaaagagtt caagtgtctg 1750

 tatatcctat ggtcttctcc atcctcacac cttctgcctt tgtcctgctc 1800

 ccttttaagc caggttacat tctaaaaatt cttaactttt aacataatat 1850

 tttataccaa agccaataaa tgaactgcat atgaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1935

<210> 1632
<211> 255
<212> PRT
<213> Homo sapien

<400> 1632
 Met Gly Asn Ser Cys Tyr Asn Ile Val Ala Thr Leu Leu Leu Val
   1               5                  10                  15

 Leu Asn Phe Glu Arg Thr Arg Ser Leu Gln Asp Pro Cys Ser Asn
                  20                  25                  30

 Cys Pro Ala Gly Thr Phe Cys Asp Asn Asn Arg Asn Gln Ile Cys
                  35                  40                  45

 Ser Pro Cys Pro Pro Asn Ser Phe Ser Ser Ala Gly Gly Gln Arg
                  50                  55                  60

 Thr Cys Asp Ile Cys Arg Gln Cys Lys Gly Val Phe Arg Thr Arg
                  65                  70                  75

 Lys Glu Cys Ser Ser Thr Ser Asn Ala Glu Cys Asp Cys Thr Pro
                  80                  85                  90

 Gly Phe His Cys Leu Gly Ala Gly Cys Ser Met Cys Glu Gln Asp
                  95                 100                 105

 Cys Lys Gln Gly Gln Glu Leu Thr Lys Lys Gly Cys Lys Asp Cys
                 110                 115                 120

 Cys Phe Gly Thr Phe Asn Asp Gln Lys Arg Gly Ile Cys Arg Pro
                 125                 130                 135

 Trp Thr Asn Cys Ser Leu Asp Gly Lys Ser Val Leu Val Asn Gly
                 140                 145                 150

 Thr Lys Glu Arg Asp Val Val Cys Gly Pro Ser Pro Ala Asp Leu
                 155                 160                 165

 Ser Pro Gly Ala Ser Ser Val Thr Pro Pro Ala Pro Ala Arg Glu
                 170                 175                 180

 Pro Gly His Ser Pro Gln Ile Ile Ser Phe Phe Leu Ala Leu Thr
                 185                 190                 195

 Ser Thr Ala Leu Leu Phe Leu Leu Phe Phe Leu Thr Leu Arg Phe
                 200                 205                 210

 Ser Val Val Lys Arg Gly Arg Lys Lys Leu Leu Tyr Ile Phe Lys
                 215                 220                 225

 Gln Pro Phe Met Arg Pro Val Gln Thr Thr Gln Glu Glu Asp Gly
                 230                 235                 240

 Cys Ser Cys Arg Phe Pro Glu Glu Glu Glu Gly Gly Cys Glu Leu
                 245                 250                 255

<210> 1633
<211> 921
<212> DNA
<213> Homo sapien

<400> 1633
 ttctatgcaa agcaaaaagc cagcagcagc cccaagctga taagattaat 50

 ctaaagagca aattatggtg taatttccta tgctgaaact ttgtagttaa 100

 ttttttaaaa aggtttcatt ttcctattgg tctgatttca caggaacatt 150

 ttacctgttt gtgaggcatt ttttctcctg gaagagaggt gctgattggc 200

 cccaagtgac tgacaatctg gtgtaacgaa aatttccaat gtaaactcat 250

 tttccctcgg tttcagcaat tttaaatcta tatatagaga tatctttgtc 300

 agcattgcat cgttagcttc tcctgataaa ctaattgcct cacattgtca 350

 ctgcaaatcg acacctatta atgggtctca cctcccaact gcttccccct 400

 ctgttcttcc tgctagcatg tgccggcaac tttgtccacg gacacaagtg 450

 cgatatcacc ttacaggaga tcatcaaaac tttgaacagc ctcacagagc 500

 agaagactct gtgcaccgag ttgaccgtaa cagacatctt tgctgcctcc 550

 aagaacacaa ctgagaagga aaccttctgc agggctgcga ctgtgctccg 600

 gcagttctac agccaccatg agaaggacac tcgctgcctg ggtgcgactg 650

 cacagcagtt ccacaggcac aagcagctga tccgattcct gaaacggctc 700

 gacaggaacc tctggggcct ggcgggcttg aattcctgtc ctgtgaagga 750

 agccaaccag agtacgttgg aaaacttctt ggaaaggcta aagacgatca 800

 tgagagagaa atattcaaag tgttcgagct gaatatttta atttatgagt 850

 ttttgatagc tttatttttt aagtatttat atatttataa ctcatcataa 900

 aataaagtat atatagaatc t 921

<210> 1634
<211> 153
<212> PRT
<213> Homo sapien

<400> 1634
 Met Gly Leu Thr Ser Gln Leu Leu Pro Pro Leu Phe Phe Leu Leu
   1               5                  10                  15

 Ala Cys Ala Gly Asn Phe Val His Gly His Lys Cys Asp Ile Thr
                  20                  25                  30

 Leu Gln Glu Ile Ile Lys Thr Leu Asn Ser Leu Thr Glu Gln Lys
                  35                  40                  45

 Thr Leu Cys Thr Glu Leu Thr Val Thr Asp Ile Phe Ala Ala Ser
                  50                  55                  60

 Lys Asn Thr Thr Glu Lys Glu Thr Phe Cys Arg Ala Ala Thr Val
                  65                  70                  75

 Leu Arg Gln Phe Tyr Ser His His Glu Lys Asp Thr Arg Cys Leu
                  80                  85                  90

 Gly Ala Thr Ala Gln Gln Phe His Arg His Lys Gln Leu Ile Arg
                  95                 100                 105

 Phe Leu Lys Arg Leu Asp Arg Asn Leu Trp Gly Leu Ala Gly Leu
                 110                 115                 120

 Asn Ser Cys Pro Val Lys Glu Ala Asn Gln Ser Thr Leu Glu Asn
                 125                 130                 135

 Phe Leu Glu Arg Leu Lys Thr Ile Met Arg Glu Lys Tyr Ser Lys
                 140                 145                 150

 Cys Ser Ser


<210> 1635
<211> 921
<212> DNA
<213> Homo sapien

<400> 1635
 ttctatgcaa agcaaaaagc cagcagcagc cccaagctga taagattaat 50

 ctaaagagca aattatggtg taatttccta tgctgaaact ttgtagttaa 100

 ttttttaaaa aggtttcatt ttcctattgg tctgatttca caggaacatt 150

 ttacctgttt gtgaggcatt ttttctcctg gaagagaggt gctgattggc 200

 cccaagtgac tgacaatctg gtgtaacgaa aatttccaat gtaaactcat 250

 tttccctcgg tttcagcaat tttaaatcta tatatagaga tatctttgtc 300

 agcattgcat cgttagcttc tcctgataaa ctaattgcct cacattgtca 350

 ctgcaaatcg acacctatta atgggtctca cctcccaact gcttccccct 400

 ctgttcttcc tgctagcatg tgccggcaac tttgtccacg gacacaagtg 450

 cgatatcacc ttacaggaga tcatcaaaac tttgaacagc ctcacagagc 500

 agaagactct gtgcaccgag ttgaccgtaa cagacatctt tgctgcctcc 550

 aagaacacaa ctgagaagga aaccttctgc agggctgcga ctgtgctccg 600

 gcagttctac agccaccatg agaaggacac tcgctgcctg ggtgcgactg 650

 cacagcagtt ccacaggcac aagcagctga tccgattcct gaaacggctc 700

 gacaggaacc tctggggcct ggcgggcttg aattcctgtc ctgtgaagga 750

 agccaaccag agtacgttgg aaaacttctt ggaaaggcta aagacgatca 800

 tgagagagaa atattcaaag tgttcgagct gaatatttta atttatgagt 850

 ttttgatagc tttatttttt aagtatttat atatttataa ctcatcataa 900

 aataaagtat atatagaatc t 921

<210> 1636
<211> 153
<212> PRT
<213> Homo sapien

<400> 1636
 Met Gly Leu Thr Ser Gln Leu Leu Pro Pro Leu Phe Phe Leu Leu
   1               5                  10                  15

 Ala Cys Ala Gly Asn Phe Val His Gly His Lys Cys Asp Ile Thr
                  20                  25                  30

 Leu Gln Glu Ile Ile Lys Thr Leu Asn Ser Leu Thr Glu Gln Lys
                  35                  40                  45

 Thr Leu Cys Thr Glu Leu Thr Val Thr Asp Ile Phe Ala Ala Ser
                  50                  55                  60

 Lys Asn Thr Thr Glu Lys Glu Thr Phe Cys Arg Ala Ala Thr Val
                  65                  70                  75

 Leu Arg Gln Phe Tyr Ser His His Glu Lys Asp Thr Arg Cys Leu
                  80                  85                  90

 Gly Ala Thr Ala Gln Gln Phe His Arg His Lys Gln Leu Ile Arg
                  95                 100                 105

 Phe Leu Lys Arg Leu Asp Arg Asn Leu Trp Gly Leu Ala Gly Leu
                 110                 115                 120

 Asn Ser Cys Pro Val Lys Glu Ala Asn Gln Ser Thr Leu Glu Asn
                 125                 130                 135

 Phe Leu Glu Arg Leu Lys Thr Ile Met Arg Glu Lys Tyr Ser Lys
                 140                 145                 150

 Cys Ser Ser


<210> 1637
<211> 2343
<212> DNA
<213> Homo sapien

<400> 1637
 cggccccccc cggccacggc gcaccgcctc cccgcccccg cccgccctcc 50

 cccaccgcgc gcgctccgcc cgccccggag cctcgccctc cgccacgatg 100

 agcaaatgag cgcgagcgag ggcatgaaat ttaaattcca ctcaggggag 150

 aaagtgctgt gcttcgagcc tgaccccacc aaggcgcgag tgctgtacga 200

 tgccaagatt gttgtagtta ttgttgggaa agacgaaaaa ggcagaaaga 250

 tcccagaata tctgatccat tttaatggtt ggaacagaag ctgggataga 300

 tgggcagcag aagatcatgt gcttcgtgat accgatgaaa atcgtagatt 350

 acagcgtaaa ttggcaagaa aagctgtagc tcgcctgagg agcacaggaa 400

 gaaagaagaa gcgctgcagg ttgcctggtg tggactctgt cttaaaaggc 450

 ctccccactg aagaaaaaga tgaaaatgat gaaaactcat taagcagttc 500

 ctctgactgt agtgaaaaca aggatgaaga aataagtgaa gaaagtgata 550

 ttgaagaaaa gactgaagtg aaagaagaac cagagcttca aacaagaagg 600

 gaaatggaag aaagaacaat aactatagaa atccctgaag ttctgaagaa 650

 gcagctggag gatgattgtt actacattaa caggaggaaa cggttagtga 700

 aacttccatg ccagaccaac atcataacga ttttggaatc ctatgtgaag 750

 cattttgcta tcaatgcagc cttttcagcc aatgagaggc ctcgtcacca 800

 tcacgttatg ccacatgcca acatgaacgt gcattatatc ccagcagaaa 850

 agaatgttga cctttgtaag gagatggtgg atggattaag aataaccttt 900

 gattacactc tcccgttggt tttactctat ccatatgaac aagctcagta 950

 taaaaaggtg acttcgtcta aattttttct tccaattaag gaaagtgcca 1000

 caagcactaa caggagccag gaggaactct ctcccagtcc gcctttgttg 1050

 aatccatcca cgccacagtc cacagagagt cagccgacca ccggtgaacc 1100

 agccaccccc aaaaggcgca aagctgagcc agaagcattg cagtctctga 1150

 ggcggtccac gcgccacagt gccaactgtg acaggctttc tgagagcagc 1200

 gcttcacctc agcccaagcg ccggcagcag gacacatccg ccagcatgcc 1250

 caagctcttc ctgcacctgg aaaagaagac acctgtgcat agcagatcat 1300

 cttcacctat tcctctgact cctagcaagg aagggagtgc tgtgtttgct 1350

 ggctttgaag ggagaagaac taatgaaata aacgaggtcc tctcctggaa 1400

 gcttgtgcct gacaattacc ccccaggtga ccagccgcct ccaccctctt 1450

 acatttatgg ggcacaacat ttgctgcgat tgtttgtgaa acttccagaa 1500

 atccttggaa agatgtcctt ttctgagaag aatctgaagg ctttattgaa 1550

 gcactttgat ctctttttga ggtttttagc agaataccac gatgacttct 1600

 tcccagagtc ggcttatgtc gctgcctgtg aggcacatta cagcaccaag 1650

 aacccccggg caatttatta aaatgttgtt ggttctgtaa gagcaactgc 1700

 tctgtctagt ttggcgctct gggttccagg tgaataacta acaaggtggt 1750

 gggtctttac ccacagcgca aacacaatgc ccaccttggg gctctgttgt 1800

 ttgagttgcc cacatactgc agttattctg ttaggaatga ttccctgggt 1850

 gcctgaaagt gctctgacac gacacttgtt actttgcagg ccatctgtga 1900

 tggcaaggaa aaagcaacta tgttcacagt gaaatattcg tggaataggt 1950

 taggccattt cagtagacat tgcagttagt tagcaagaac cacattgtct 2000

 ctttatttgt tagcattaaa caaatttttt tttgcaaatt ggttttattt 2050

 ttttgatgaa gccgagcaac tctgtccaaa aaggtttagt ttgtactcgg 2100

 aaaccacaaa gtagtctcaa agtattttag agggaatcga tattgatggc 2150

 aaaagaaaat ttgcagctat gcatttgctt ctaacggttc cctctctgtg 2200

 aaacattatt tttggtgatc taaagaaagc attgcctttc ttatttgaga 2250

 ttttacagct atactttgtt gtgtaatgtt atggttccct ttctgtaaaa 2300

 tgttattttt ggtgatctaa ataaagcctg tcttgtttga aag 2343

<210> 1638
<211> 521
<212> PRT
<213> Homo sapien

<400> 1638
 Met Ser Ala Ser Glu Gly Met Lys Phe Lys Phe His Ser Gly Glu
   1               5                  10                  15

 Lys Val Leu Cys Phe Glu Pro Asp Pro Thr Lys Ala Arg Val Leu
                  20                  25                  30

 Tyr Asp Ala Lys Ile Val Val Val Ile Val Gly Lys Asp Glu Lys
                  35                  40                  45

 Gly Arg Lys Ile Pro Glu Tyr Leu Ile His Phe Asn Gly Trp Asn
                  50                  55                  60

 Arg Ser Trp Asp Arg Trp Ala Ala Glu Asp His Val Leu Arg Asp
                  65                  70                  75

 Thr Asp Glu Asn Arg Arg Leu Gln Arg Lys Leu Ala Arg Lys Ala
                  80                  85                  90

 Val Ala Arg Leu Arg Ser Thr Gly Arg Lys Lys Lys Arg Cys Arg
                  95                 100                 105

 Leu Pro Gly Val Asp Ser Val Leu Lys Gly Leu Pro Thr Glu Glu
                 110                 115                 120

 Lys Asp Glu Asn Asp Glu Asn Ser Leu Ser Ser Ser Ser Asp Cys
                 125                 130                 135

 Ser Glu Asn Lys Asp Glu Glu Ile Ser Glu Glu Ser Asp Ile Glu
                 140                 145                 150

 Glu Lys Thr Glu Val Lys Glu Glu Pro Glu Leu Gln Thr Arg Arg
                 155                 160                 165

 Glu Met Glu Glu Arg Thr Ile Thr Ile Glu Ile Pro Glu Val Leu
                 170                 175                 180

 Lys Lys Gln Leu Glu Asp Asp Cys Tyr Tyr Ile Asn Arg Arg Lys
                 185                 190                 195

 Arg Leu Val Lys Leu Pro Cys Gln Thr Asn Ile Ile Thr Ile Leu
                 200                 205                 210

 Glu Ser Tyr Val Lys His Phe Ala Ile Asn Ala Ala Phe Ser Ala
                 215                 220                 225

 Asn Glu Arg Pro Arg His His His Val Met Pro His Ala Asn Met
                 230                 235                 240

 Asn Val His Tyr Ile Pro Ala Glu Lys Asn Val Asp Leu Cys Lys
                 245                 250                 255

 Glu Met Val Asp Gly Leu Arg Ile Thr Phe Asp Tyr Thr Leu Pro
                 260                 265                 270

 Leu Val Leu Leu Tyr Pro Tyr Glu Gln Ala Gln Tyr Lys Lys Val
                 275                 280                 285

 Thr Ser Ser Lys Phe Phe Leu Pro Ile Lys Glu Ser Ala Thr Ser
                 290                 295                 300

 Thr Asn Arg Ser Gln Glu Glu Leu Ser Pro Ser Pro Pro Leu Leu
                 305                 310                 315

 Asn Pro Ser Thr Pro Gln Ser Thr Glu Ser Gln Pro Thr Thr Gly
                 320                 325                 330

 Glu Pro Ala Thr Pro Lys Arg Arg Lys Ala Glu Pro Glu Ala Leu
                 335                 340                 345

 Gln Ser Leu Arg Arg Ser Thr Arg His Ser Ala Asn Cys Asp Arg
                 350                 355                 360

 Leu Ser Glu Ser Ser Ala Ser Pro Gln Pro Lys Arg Arg Gln Gln
                 365                 370                 375

 Asp Thr Ser Ala Ser Met Pro Lys Leu Phe Leu His Leu Glu Lys
                 380                 385                 390

 Lys Thr Pro Val His Ser Arg Ser Ser Ser Pro Ile Pro Leu Thr
                 395                 400                 405

 Pro Ser Lys Glu Gly Ser Ala Val Phe Ala Gly Phe Glu Gly Arg
                 410                 415                 420

 Arg Thr Asn Glu Ile Asn Glu Val Leu Ser Trp Lys Leu Val Pro
                 425                 430                 435

 Asp Asn Tyr Pro Pro Gly Asp Gln Pro Pro Pro Pro Ser Tyr Ile
                 440                 445                 450

 Tyr Gly Ala Gln His Leu Leu Arg Leu Phe Val Lys Leu Pro Glu
                 455                 460                 465

 Ile Leu Gly Lys Met Ser Phe Ser Glu Lys Asn Leu Lys Ala Leu
                 470                 475                 480

 Leu Lys His Phe Asp Leu Phe Leu Arg Phe Leu Ala Glu Tyr His
                 485                 490                 495

 Asp Asp Phe Phe Pro Glu Ser Ala Tyr Val Ala Ala Cys Glu Ala
                 500                 505                 510

 His Tyr Ser Thr Lys Asn Pro Arg Ala Ile Tyr
                 515                 520

<210> 1639
<211> 2366
<212> DNA
<213> Homo sapien

<400> 1639
 gaccacgcgt atcgatgtcg acccacagga ttgtcacaga gggcagggtg 50

 gtgactgagg accagctcct catgcttgag gctgtggtga tgcacctcgg 100

 gatccgctct gcccgctgtg tcctgggcat ggagggtcag caggtcatcc 150

 tgcacctgcc cctatcccag aaggggccct tctggacatg ggagcctagt 200

 gcccctcgaa ctctgctcca ggtcctacag gatccagccc tgaaagacct 250

 cgtcctcacc tgccccaccc tgccctggca ttccctgatc ctgcggcccc 300

 agtatgagat ccaagccatc atgcacatgc gcaggaccat tgtcaagatc 350

 ccttctaccc tggaggtcga cgtggaggac gtcaccgcct cctcccggca 400

 cgtccacttt atcaaaccgc tgctgctgag cgaggtcctg gcctgggaag 450

 gccctttccc cctgtccatg gagatcctgg aggttcctga gggccgcccc 500

 atcttcctca gcccgtgggt gggctccttg caaaaaggcc agaggctttg 550

 cgtctatggc ctagcctcac caccctggcg ggtcctggcc tcaagcaagg 600

 gccgcaaggt gcccaggcac ttcctggtgt cagggggcta ccaaggcaag 650

 ctgcggcggc ggccaaggga gttccccacg gcctatgacc tcctaggtgc 700

 tttccagcca ggccggccac tccgggtggt ggccacaaag gactgtgagg 750

 gcgagaggga ggagaatccc gagttcacgt ccctggctgt gggtgaccgg 800

 ctggaggtgc tggggcctgg ccaggcccat ggggcccagg gcagtgacgt 850

 ggatgtcttg gtttgtcagc ggctgagtga ccaggctggg gaagatgagg 900

 aggaagagtg caaagaggag gcagagaccc agagcgggtc ctgctgccct 950

 tccacttccc tggcagtttc gtggaggaga tgagtgacag ccggcgctac 1000

 agcctggcag atctgactgc ccagttttca atgccttgtg aggtcaaggt 1050

 ggtggccaag gacaccagcc accccaatga ccctcagaac ctccttcctg 1100

 ggcctgcggc tggaggagaa gatcacagag ccattcttgg tggtgagcct 1150

 ggactctgag ctgggatgtg ctttgagatc cctccccgga ggctggacct 1200

 gactgtcgtg gaggccaagg ggcagccaga cttgccagag gggtctctcc 1250

 ccatagccac agtggaggaa gctggaacag acacctttta ttattgtctt 1300

 cggaagttac cagcctgtga gatccaagcc cccccaccca ggccccctaa 1350

 aaatcagggc ctcagcaagc agaggagaca cagcagtgag ggaggcgtca 1400

 agtcttctca agtcttagga ttgcagcaac acgttcggct gcccaaaccc 1450

 aaggcgaaga ccttgccaga gttcatcaag gatggctcca gtacgtacag 1500

 caagattcct gcccacagga agggccacag gcccgctaag ccccaaaggc 1550

 aggatctaga tgatgatgaa catgattatg aagaaatact tgagcaattt 1600

 cagaaaacca tctaagtgct ggaggaacca cgcttcctaa ctgctgcttc 1650

 tcagggaatc cgacaccagc caaccatttt aagcctctaa aagacctcgg 1700

 gcaagtctca cagaaactga gctgcagacg gggagtagct ttgtggaaac 1750

 tgatttgatg gacactgcac cagcttcctt caggttctag attcttgcta 1800

 cttagggcgg gctggtttgg acctaacatc tcgcacgtga ctccctcagc 1850

 ctcagagcct tgggatgcag agcagctggc agggttcctc tcaatcctgc 1900

 aaccccagct gtcccaccgg tggatgcaga ggggaatccg aggccatcaa 1950

 ccttggtgac agcagcgcag tgccaatgct gatcacactg catgggagat 2000

 tttgttaacg tctgccaccc ccactctcac ccccaagctc taagcccccg 2050

 ggaggcctgg actgtcttcc tcatctctgt agcaccaagc ctgatagatc 2100

 tgtatatggt aaacaggggt ttaaccacat gtggttaaca tggattaatg 2150

 tgggaatttg gcttcaagaa cacaacctta ggaccttggg ccccaaaagc 2200

 tggtggtgaa atgagaggag ccaatttaag aagaccctta tggagacctg 2250

 aggctgcaga aactggtagg tttcatcagg tggttaaagt cgtcaaagtt 2300

 gtaagtgact aaccaagatt atttcatttt aaaaccacag aataaaaatg 2350

 acacctgagc ttctcc 2366

<210> 1640
<211> 284
<212> PRT
<213> Homo sapien

<400> 1640
 Met Glu Gly Gln Gln Val Ile Leu His Leu Pro Leu Ser Gln Lys
   1               5                  10                  15

 Gly Pro Phe Trp Thr Trp Glu Pro Ser Ala Pro Arg Thr Leu Leu
                  20                  25                  30

 Gln Val Leu Gln Asp Pro Ala Leu Lys Asp Leu Val Leu Thr Cys
                  35                  40                  45

 Pro Thr Leu Pro Trp His Ser Leu Ile Leu Arg Pro Gln Tyr Glu
                  50                  55                  60

 Ile Gln Ala Ile Met His Met Arg Arg Thr Ile Val Lys Ile Pro
                  65                  70                  75

 Ser Thr Leu Glu Val Asp Val Glu Asp Val Thr Ala Ser Ser Arg
                  80                  85                  90

 His Val His Phe Ile Lys Pro Leu Leu Leu Ser Glu Val Leu Ala
                  95                 100                 105

 Trp Glu Gly Pro Phe Pro Leu Ser Met Glu Ile Leu Glu Val Pro
                 110                 115                 120

 Glu Gly Arg Pro Ile Phe Leu Ser Pro Trp Val Gly Ser Leu Gln
                 125                 130                 135

 Lys Gly Gln Arg Leu Cys Val Tyr Gly Leu Ala Ser Pro Pro Trp
                 140                 145                 150

 Arg Val Leu Ala Ser Ser Lys Gly Arg Lys Val Pro Arg His Phe
                 155                 160                 165

 Leu Val Ser Gly Gly Tyr Gln Gly Lys Leu Arg Arg Arg Pro Arg
                 170                 175                 180

 Glu Phe Pro Thr Ala Tyr Asp Leu Leu Gly Ala Phe Gln Pro Gly
                 185                 190                 195

 Arg Pro Leu Arg Val Val Ala Thr Lys Asp Cys Glu Gly Glu Arg
                 200                 205                 210

 Glu Glu Asn Pro Glu Phe Thr Ser Leu Ala Val Gly Asp Arg Leu
                 215                 220                 225

 Glu Val Leu Gly Pro Gly Gln Ala His Gly Ala Gln Gly Ser Asp
                 230                 235                 240

 Val Asp Val Leu Val Cys Gln Arg Leu Ser Asp Gln Ala Gly Glu
                 245                 250                 255

 Asp Glu Glu Glu Glu Cys Lys Glu Glu Ala Glu Thr Gln Ser Gly
                 260                 265                 270

 Ser Cys Cys Pro Ser Thr Ser Leu Ala Val Ser Trp Arg Arg
                 275                 280

<210> 1641
<211> 1121
<212> DNA
<213> Homo sapien

<400> 1641
 ctagctctgt gggaaggttt tgggctctct ggctcggatt ttgcaatttc 50

 tccctgggga ctgccgtgga gccgcatcca ctgtggatta taattgcaac 100

 atgacgctgg aagagctcgt ggcgtgcgac aacgcggcgc agaagatgca 150

 gacggtgacc gccgcggtgg aggagctttt ggtggccgct cagcgccagg 200

 atcgcctcac agtgggggtg tacgagtcgg ccaagttgat gaatgtggac 250

 ccagacagcg tggtcctctg cctcttggcc attgacgagg aggaggagga 300

 tgacatcgcc ctgcaaatcc acttcacgct catccagtcc ttctgctgtg 350

 acaacgacat caacatcgtg cgggtgtcgg gcaatgcgcg cctggcgcag 400

 ctcctgggag agccggccga gacccagggc accaccgagg cccgagacct 450

 ccactgtctt cccttcctac agaaccctca cacggacgcc tggaagagcc 500

 acggcttggt ggaggtggcc agctactgcg aagaaagccg gggcaacaac 550

 cagtgggtcc cctacatctc tcttcaggaa cgctgaggcc cttcccagca 600

 gcagaatctg ttgagttgct gccaacaaac aaaaaataca ataaatattt 650

 gaaccccctc ccccccagca caaccccccc aaaacaaccc aacccacgag 700

 gaccatcggg ggcaggtcgt tggagactga agagaaagag agagaggaga 750

 agggagtgag gggccgctgc cgccttcccc atcacggagg gtccagactg 800

 tccactcggg ggtggagtga gactgactgc aagccccacc ctccttgaga 850

 ctggagctga gcgtctgcat acgagagact tggttgaaac ttggttggtc 900

 cttgtctgca ccctcgacaa gaccacactt tgggacttgg gagctggggc 950

 tgaagttgct ctgtacccat gaactcccag tttgcgaatt aataagagac 1000

 aatctatttt gttacttgca cttgttattc gaaccactga gagcgagatg 1050

 ggaagcatag atatctatat ttttatttct actatgaggg ccttgtaata 1100

 aatttctaaa gcctcaaaaa a 1121

<210> 1642
<211> 161
<212> PRT
<213> Homo sapien

<400> 1642
 Met Thr Leu Glu Glu Leu Val Ala Cys Asp Asn Ala Ala Gln Lys
   1               5                  10                  15

 Met Gln Thr Val Thr Ala Ala Val Glu Glu Leu Leu Val Ala Ala
                  20                  25                  30

 Gln Arg Gln Asp Arg Leu Thr Val Gly Val Tyr Glu Ser Ala Lys
                  35                  40                  45

 Leu Met Asn Val Asp Pro Asp Ser Val Val Leu Cys Leu Leu Ala
                  50                  55                  60

 Ile Asp Glu Glu Glu Glu Asp Asp Ile Ala Leu Gln Ile His Phe
                  65                  70                  75

 Thr Leu Ile Gln Ser Phe Cys Cys Asp Asn Asp Ile Asn Ile Val
                  80                  85                  90

 Arg Val Ser Gly Asn Ala Arg Leu Ala Gln Leu Leu Gly Glu Pro
                  95                 100                 105

 Ala Glu Thr Gln Gly Thr Thr Glu Ala Arg Asp Leu His Cys Leu
                 110                 115                 120

 Pro Phe Leu Gln Asn Pro His Thr Asp Ala Trp Lys Ser His Gly
                 125                 130                 135

 Leu Val Glu Val Ala Ser Tyr Cys Glu Glu Ser Arg Gly Asn Asn
                 140                 145                 150

 Gln Trp Val Pro Tyr Ile Ser Leu Gln Glu Arg
                 155                 160

<210> 1643
<211> 2089
<212> DNA
<213> Homo sapien

<400> 1643
 gtttgagcag cattgttaga gcctgtggaa aacactttac aactgtgtaa 50

 ctgtcttcat ctttacagag gaatagtcta caaaggaaga cttgtaacct 100

 ggagaagaga cctgtcattt actccatcct ttatagtgat gctacaggac 150

 gaagaggaat ggataaaaac attggcgagc aactcaataa agcgtatgaa 200

 gccttccggc aggcatgcat ggatagagat tctgcagtaa aagaattaca 250

 gcaaaagact gagaactatg agcagagaat acgtgaacaa caggaacagc 300

 tgtcacttca acagactatt attgacaagc taaaatctca gttacttctt 350

 gtgaattcca ctcaagataa caattatggc tgtgttcctc tgcttgaaga 400

 cagtgaaaca agaaagaata atttgactct tgatcagcca caagataaag 450

 tgatttcagg aatagcaaga gaaaaactac caaaggtaag aagacaagag 500

 gtttcttctc ctagaaaaga aacttcagca aggagtcttg gcagtccttt 550

 gctccatgaa aggggtaata tagagaagac tttctgggat ctgaaagaag 600

 aatttcataa aatatgcatg ctagcaaaag cacagaaaga ccacttaagc 650

 aaacttaata taccagacac tgcaactgaa acacagtgct ctgtgcctat 700

 acagtgtacg gataaaacag ataaacaaga agcgctgttt aagcctcagg 750

 ctaaagatga tataaataga ggtgcaccat ccatcacatc tgtcacacca 800

 agaggactgt gcagagatga ggaagacacc tcttttgaat cactttctaa 850

 attcaatgtc aagtttccac ctatggacaa tgactcaact ttcttacata 900

 gcactccaga gagacccggc atccttagtc ctgccacgtc tgaggcagtg 950

 tgccaagaga aatttaatat ggagttcaga gacaacccag ggaactttgt 1000

 taaaacagaa gaaactttat ttgaaattca gggaattgac cccatagctt 1050

 cagctataca aaaccttaaa acaactgaca aaacaaagcc ctcaaatctc 1100

 gtaaacactt gtatcaggac aactctggat agagctgcgt gtttgccacc 1150

 tggagaccat aatgcattat atgtaaatag cttcccactt ctggacccat 1200

 ctgatgcacc ttttccctca ctcgattccc cgggaaaagc aatccgagga 1250

 ccacagcagc ccatttggaa gccctttcct aatcaagaca gtgactcggt 1300

 ggtactaagt ggcacagact cagaactgca tatacctcga gtatgtgaat 1350

 tctgtcaagc agttttccca ccatccatta catccagggg ggatttcctt 1400

 cggcatctta attcacactt caatggagag acttaagaca catttgaaaa 1450

 cagacatatc aagttctatg tgatgatttt gggtttttaa tactataaat 1500

 acttgattgt aaactaaatt caagatcatt tataggaaaa tctagtttca 1550

 cagctatttg aatttttttc tggatttact atataactct tattttttaa 1600

 aagatcattc tgttctttca aggagaaata agcctaaaag aagaaaaaca 1650

 aaaaaaattc tgtataaaac tgtaatcctt tgtattcatg tttacagtgc 1700

 tattactata attcaaaatt atgtatgtga cttagagtta tataatcata 1750

 atttatgttt atttcaaata tctaagttta ttgcttggat ttctagtgag 1800

 agctgttgaa tttggtgatg tcaaatgttt ctagggtttt tttagtttgt 1850

 ttttattgaa aaatttaatt atttatgcta taggtgatat tctctttgaa 1900

 taaacctata atagaaaata gcagacaaca taaacatctt tgtaaatatc 1950

 aaacctaata catttcttgt ccagtgataa aacaactggt agaattattt 2000

 aaacacttta gatttttaaa taatatacat ggctttaatt tttactgtgt 2050

 gtatagctac atgatgaaat taattaaata ttaagaggt 2089

<210> 1644
<211> 425
<212> PRT
<213> Homo sapien

<400> 1644
 Met Asp Lys Asn Ile Gly Glu Gln Leu Asn Lys Ala Tyr Glu Ala
   1               5                  10                  15

 Phe Arg Gln Ala Cys Met Asp Arg Asp Ser Ala Val Lys Glu Leu
                  20                  25                  30

 Gln Gln Lys Thr Glu Asn Tyr Glu Gln Arg Ile Arg Glu Gln Gln
                  35                  40                  45

 Glu Gln Leu Ser Leu Gln Gln Thr Ile Ile Asp Lys Leu Lys Ser
                  50                  55                  60

 Gln Leu Leu Leu Val Asn Ser Thr Gln Asp Asn Asn Tyr Gly Cys
                  65                  70                  75

 Val Pro Leu Leu Glu Asp Ser Glu Thr Arg Lys Asn Asn Leu Thr
                  80                  85                  90

 Leu Asp Gln Pro Gln Asp Lys Val Ile Ser Gly Ile Ala Arg Glu
                  95                 100                 105

 Lys Leu Pro Lys Val Arg Arg Gln Glu Val Ser Ser Pro Arg Lys
                 110                 115                 120

 Glu Thr Ser Ala Arg Ser Leu Gly Ser Pro Leu Leu His Glu Arg
                 125                 130                 135

 Gly Asn Ile Glu Lys Thr Phe Trp Asp Leu Lys Glu Glu Phe His
                 140                 145                 150

 Lys Ile Cys Met Leu Ala Lys Ala Gln Lys Asp His Leu Ser Lys
                 155                 160                 165

 Leu Asn Ile Pro Asp Thr Ala Thr Glu Thr Gln Cys Ser Val Pro
                 170                 175                 180

 Ile Gln Cys Thr Asp Lys Thr Asp Lys Gln Glu Ala Leu Phe Lys
                 185                 190                 195

 Pro Gln Ala Lys Asp Asp Ile Asn Arg Gly Ala Pro Ser Ile Thr
                 200                 205                 210

 Ser Val Thr Pro Arg Gly Leu Cys Arg Asp Glu Glu Asp Thr Ser
                 215                 220                 225

 Phe Glu Ser Leu Ser Lys Phe Asn Val Lys Phe Pro Pro Met Asp
                 230                 235                 240

 Asn Asp Ser Thr Phe Leu His Ser Thr Pro Glu Arg Pro Gly Ile
                 245                 250                 255

 Leu Ser Pro Ala Thr Ser Glu Ala Val Cys Gln Glu Lys Phe Asn
                 260                 265                 270

 Met Glu Phe Arg Asp Asn Pro Gly Asn Phe Val Lys Thr Glu Glu
                 275                 280                 285

 Thr Leu Phe Glu Ile Gln Gly Ile Asp Pro Ile Ala Ser Ala Ile
                 290                 295                 300

 Gln Asn Leu Lys Thr Thr Asp Lys Thr Lys Pro Ser Asn Leu Val
                 305                 310                 315

 Asn Thr Cys Ile Arg Thr Thr Leu Asp Arg Ala Ala Cys Leu Pro
                 320                 325                 330

 Pro Gly Asp His Asn Ala Leu Tyr Val Asn Ser Phe Pro Leu Leu
                 335                 340                 345

 Asp Pro Ser Asp Ala Pro Phe Pro Ser Leu Asp Ser Pro Gly Lys
                 350                 355                 360

 Ala Ile Arg Gly Pro Gln Gln Pro Ile Trp Lys Pro Phe Pro Asn
                 365                 370                 375

 Gln Asp Ser Asp Ser Val Val Leu Ser Gly Thr Asp Ser Glu Leu
                 380                 385                 390

 His Ile Pro Arg Val Cys Glu Phe Cys Gln Ala Val Phe Pro Pro
                 395                 400                 405

 Ser Ile Thr Ser Arg Gly Asp Phe Leu Arg His Leu Asn Ser His
                 410                 415                 420

 Phe Asn Gly Glu Thr
                 425

<210> 1645
<211> 3122
<212> DNA
<213> Homo sapien

<400> 1645
 cgctgcggcc gctatcccct ccggaccatg gccgacgacg acgtgctgtt 50

 cgaggatgtg tacgagctgt gcgaggtgat cggaaagggt cccttcagtg 100

 ttgtacgacg atgtatcaac agagaaactg ggcaacaatt tgctgtaaaa 150

 attgttgatg tagccaagtt cacatcaagt ccagggttaa gtacagaaga 200

 tctaaagcgg gaagccagta tctgtcatat gctgaaacat ccacacattg 250

 tagagttatt ggagacatat agctcagatg gaatgcttta catggttttc 300

 gaatttatgg atggagcaga tctgtgtttt gaaatcgtaa agcgagctga 350

 cgctggtttt gtgtacagtg aagctgtagc cagccattat atgagacaga 400

 tactggaagc tctacgctac tgccatgata ataacataat tcacagggat 450

 gtgaagcccc actgtgttct ccttgcctca aaagaaaact cggcacctgt 500

 taaacttgga ggctttgggg tagctattca attaggggag tctggacttg 550

 tagctggagg acgtgttgga acacctcatt ttatggcacc agaagtggtc 600

 aaaagagagc cttacggaaa gcctgtagac gtctgggggt gcggtgtgat 650

 cctttttatc ctgctcagtg gttgtttgcc tttttacgga accaaggaaa 700

 gattgtttga aggcattatt aaaggaaaat ataagatgaa tccaaggcag 750

 tggagccata tctctgaaag tgccaaagac ctagtacgtc gcatgctgat 800

 gctggatcca gctgaaagga tcactgttta tgaagcactg aatcacccat 850

 ggcttaagga gcgggatcgt tacgcctaca agattcatct tccagaaaca 900

 gtagagcagc tgaggaaatt caatgcaagg aggaaactaa agggtgcagt 950

 actagccgct gtgtcaagtc acaaattcaa ctcattctat ggggatcccc 1000

 ctgaagagtt accagatttc tccgaagacc ctacctcctc agggcttcta 1050

 gcagcagaaa gagcagtctc acaggtgctg gacagcctgg aagagattca 1100

 tgcgcttaca gactgcagtg aaaaggacct agattttcta cacagtgttt 1150

 tccaggatca gcatcttcac acactactag atctgtatga caaaattaac 1200

 acaaagtctt caccacaaat caggaatcct ccaagcgatg cagtacagag 1250

 agccaaagag gtattggaag aaatttcatg ttaccctgag aataacgacg 1300

 caaaggaact aaagcgtatt ttaacacaac ctcatttcat ggccttactt 1350

 cagactcacg acgtagtggc acatgaagtt tacagtgatg aagcattgag 1400

 ggtcacacct cctcccacct ctccctattt aaacggcgat tctccagaaa 1450

 gtgctaacgg aggcatggat atggagaatg tgaccagagt tcggctggta 1500

 cagtttcaaa agaacacaga tgaaccaatg ggaatcactt taaaaatgaa 1550

 tgaactaaat cattgtattg ttgcaagaat tatgcatggg ggcatgattc 1600

 acaggcaagg tacacttcat gttggtgatg aaattcgaga aatcaatggc 1650

 atcagtgtgg ctaaccaaac agtggaacaa ctgcaaaaaa tgcttaggga 1700

 aatgcggggg agtattacct tcaagattgt gccaagttac cgcactcagt 1750

 cttcgtcctg tgagagagat tccccttcca cttccagaca gtccccagct 1800

 aatggtcata gcagcactaa caattctgtt tcggacttgc catcaactac 1850

 ccaaccaaaa ggacgacaga tctatgtaag agcacaattt gaatatgatc 1900

 cagccaagga tgacctcatc ccctgtaaag aagctggcat tcgattcaga 1950

 gttggtgaca tcatccagat tattagtaag gatgatcata attggtggca 2000

 gggtaaactg gaaaactcca aaaatggaac tgcaggtctc attccttctt 2050

 ctgaacttca ggaatggcga gtagcttgca ttgccatgga gaagaccaaa 2100

 caggagcagc aggccagctg tacttggttt ggcaagaaaa agaagcagta 2150

 caaagataaa tatttggcaa agcacaatgc agatcttgtc acatatgaag 2200

 aagtagtaaa actgccagca ttcaagagga aaacactagt cttattaggc 2250

 gcacatggtg ttgggagaag acacataaaa aacactctca tcacaaagca 2300

 cccagaccgg tttgcgtacc ctattccaca tacaaccaga cctccaaaga 2350

 gagacgaaga aaatggaaag aattattact ttgtatctca tgaccaaatg 2400

 atgcaagaca tctctaataa cgagtacttg gagtacggca gccacgagga 2450

 tgcgatgtat gggacaaaac tggagaccat ccggaagatc cacgagcagg 2500

 ggctgattgc aatactggac gtggagcctc aggcactgaa ggtcctgaga 2550

 actgcagagt ttgctccttt tgttgttttc attgctgcac caactattac 2600

 tccaggttta aatgaggatg aatctcttca gcgtctgcag aaggagtctg 2650

 acatcttaca gagaacatat gcacactact tcgatctcac aattatcaac 2700

 aatgaaattg atgagacaat cagacatctg gaggaagctg ttgagctcgt 2750

 gtgcacagcc ccacagtggg tccctgtctc ctgggtctat taggcctctc 2800

 cccagatatc tgagcataac tgggagcacc tcatttgtgg aaaagcctct 2850

 ttgttatcgg ccttgtgtca gcaggtcatg gtccctagag actacctagt 2900

 tgtagtgtga cctacattta taattattgt catgtccgaa tagataggag 2950

 gagaaaaaca attacacact aatttaaaga gacagtatct tttttaatca 3000

 gttctcctaa actttaataa aatgtatctt taaatgtatg tattattcaa 3050

 tcctttggaa tgttatattt ttggaaatca tagcttttta tttccaaggc 3100

 ccctaaaact gcacaaaata ga 3122

<210> 1646
<211> 921
<212> PRT
<213> Homo sapien

<400> 1646
 Met Ala Asp Asp Asp Val Leu Phe Glu Asp Val Tyr Glu Leu Cys
   1               5                  10                  15

 Glu Val Ile Gly Lys Gly Pro Phe Ser Val Val Arg Arg Cys Ile
                  20                  25                  30

 Asn Arg Glu Thr Gly Gln Gln Phe Ala Val Lys Ile Val Asp Val
                  35                  40                  45

 Ala Lys Phe Thr Ser Ser Pro Gly Leu Ser Thr Glu Asp Leu Lys
                  50                  55                  60

 Arg Glu Ala Ser Ile Cys His Met Leu Lys His Pro His Ile Val
                  65                  70                  75

 Glu Leu Leu Glu Thr Tyr Ser Ser Asp Gly Met Leu Tyr Met Val
                  80                  85                  90

 Phe Glu Phe Met Asp Gly Ala Asp Leu Cys Phe Glu Ile Val Lys
                  95                 100                 105

 Arg Ala Asp Ala Gly Phe Val Tyr Ser Glu Ala Val Ala Ser His
                 110                 115                 120

 Tyr Met Arg Gln Ile Leu Glu Ala Leu Arg Tyr Cys His Asp Asn
                 125                 130                 135

 Asn Ile Ile His Arg Asp Val Lys Pro His Cys Val Leu Leu Ala
                 140                 145                 150

 Ser Lys Glu Asn Ser Ala Pro Val Lys Leu Gly Gly Phe Gly Val
                 155                 160                 165

 Ala Ile Gln Leu Gly Glu Ser Gly Leu Val Ala Gly Gly Arg Val
                 170                 175                 180

 Gly Thr Pro His Phe Met Ala Pro Glu Val Val Lys Arg Glu Pro
                 185                 190                 195

 Tyr Gly Lys Pro Val Asp Val Trp Gly Cys Gly Val Ile Leu Phe
                 200                 205                 210

 Ile Leu Leu Ser Gly Cys Leu Pro Phe Tyr Gly Thr Lys Glu Arg
                 215                 220                 225

 Leu Phe Glu Gly Ile Ile Lys Gly Lys Tyr Lys Met Asn Pro Arg
                 230                 235                 240

 Gln Trp Ser His Ile Ser Glu Ser Ala Lys Asp Leu Val Arg Arg
                 245                 250                 255

 Met Leu Met Leu Asp Pro Ala Glu Arg Ile Thr Val Tyr Glu Ala
                 260                 265                 270

 Leu Asn His Pro Trp Leu Lys Glu Arg Asp Arg Tyr Ala Tyr Lys
                 275                 280                 285

 Ile His Leu Pro Glu Thr Val Glu Gln Leu Arg Lys Phe Asn Ala
                 290                 295                 300

 Arg Arg Lys Leu Lys Gly Ala Val Leu Ala Ala Val Ser Ser His
                 305                 310                 315

 Lys Phe Asn Ser Phe Tyr Gly Asp Pro Pro Glu Glu Leu Pro Asp
                 320                 325                 330

 Phe Ser Glu Asp Pro Thr Ser Ser Gly Leu Leu Ala Ala Glu Arg
                 335                 340                 345

 Ala Val Ser Gln Val Leu Asp Ser Leu Glu Glu Ile His Ala Leu
                 350                 355                 360

 Thr Asp Cys Ser Glu Lys Asp Leu Asp Phe Leu His Ser Val Phe
                 365                 370                 375

 Gln Asp Gln His Leu His Thr Leu Leu Asp Leu Tyr Asp Lys Ile
                 380                 385                 390

 Asn Thr Lys Ser Ser Pro Gln Ile Arg Asn Pro Pro Ser Asp Ala
                 395                 400                 405

 Val Gln Arg Ala Lys Glu Val Leu Glu Glu Ile Ser Cys Tyr Pro
                 410                 415                 420

 Glu Asn Asn Asp Ala Lys Glu Leu Lys Arg Ile Leu Thr Gln Pro
                 425                 430                 435

 His Phe Met Ala Leu Leu Gln Thr His Asp Val Val Ala His Glu
                 440                 445                 450

 Val Tyr Ser Asp Glu Ala Leu Arg Val Thr Pro Pro Pro Thr Ser
                 455                 460                 465

 Pro Tyr Leu Asn Gly Asp Ser Pro Glu Ser Ala Asn Gly Gly Met
                 470                 475                 480

 Asp Met Glu Asn Val Thr Arg Val Arg Leu Val Gln Phe Gln Lys
                 485                 490                 495

 Asn Thr Asp Glu Pro Met Gly Ile Thr Leu Lys Met Asn Glu Leu
                 500                 505                 510

 Asn His Cys Ile Val Ala Arg Ile Met His Gly Gly Met Ile His
                 515                 520                 525

 Arg Gln Gly Thr Leu His Val Gly Asp Glu Ile Arg Glu Ile Asn
                 530                 535                 540

 Gly Ile Ser Val Ala Asn Gln Thr Val Glu Gln Leu Gln Lys Met
                 545                 550                 555

 Leu Arg Glu Met Arg Gly Ser Ile Thr Phe Lys Ile Val Pro Ser
                 560                 565                 570

 Tyr Arg Thr Gln Ser Ser Ser Cys Glu Arg Asp Ser Pro Ser Thr
                 575                 580                 585

 Ser Arg Gln Ser Pro Ala Asn Gly His Ser Ser Thr Asn Asn Ser
                 590                 595                 600

 Val Ser Asp Leu Pro Ser Thr Thr Gln Pro Lys Gly Arg Gln Ile
                 605                 610                 615

 Tyr Val Arg Ala Gln Phe Glu Tyr Asp Pro Ala Lys Asp Asp Leu
                 620                 625                 630

 Ile Pro Cys Lys Glu Ala Gly Ile Arg Phe Arg Val Gly Asp Ile
                 635                 640                 645

 Ile Gln Ile Ile Ser Lys Asp Asp His Asn Trp Trp Gln Gly Lys
                 650                 655                 660

 Leu Glu Asn Ser Lys Asn Gly Thr Ala Gly Leu Ile Pro Ser Ser
                 665                 670                 675

 Glu Leu Gln Glu Trp Arg Val Ala Cys Ile Ala Met Glu Lys Thr
                 680                 685                 690

 Lys Gln Glu Gln Gln Ala Ser Cys Thr Trp Phe Gly Lys Lys Lys
                 695                 700                 705

 Lys Gln Tyr Lys Asp Lys Tyr Leu Ala Lys His Asn Ala Asp Leu
                 710                 715                 720

 Val Thr Tyr Glu Glu Val Val Lys Leu Pro Ala Phe Lys Arg Lys
                 725                 730                 735

 Thr Leu Val Leu Leu Gly Ala His Gly Val Gly Arg Arg His Ile
                 740                 745                 750

 Lys Asn Thr Leu Ile Thr Lys His Pro Asp Arg Phe Ala Tyr Pro
                 755                 760                 765

 Ile Pro His Thr Thr Arg Pro Pro Lys Arg Asp Glu Glu Asn Gly
                 770                 775                 780

 Lys Asn Tyr Tyr Phe Val Ser His Asp Gln Met Met Gln Asp Ile
                 785                 790                 795

 Ser Asn Asn Glu Tyr Leu Glu Tyr Gly Ser His Glu Asp Ala Met
                 800                 805                 810

 Tyr Gly Thr Lys Leu Glu Thr Ile Arg Lys Ile His Glu Gln Gly
                 815                 820                 825

 Leu Ile Ala Ile Leu Asp Val Glu Pro Gln Ala Leu Lys Val Leu
                 830                 835                 840

 Arg Thr Ala Glu Phe Ala Pro Phe Val Val Phe Ile Ala Ala Pro
                 845                 850                 855

 Thr Ile Thr Pro Gly Leu Asn Glu Asp Glu Ser Leu Gln Arg Leu
                 860                 865                 870

 Gln Lys Glu Ser Asp Ile Leu Gln Arg Thr Tyr Ala His Tyr Phe
                 875                 880                 885

 Asp Leu Thr Ile Ile Asn Asn Glu Ile Asp Glu Thr Ile Arg His
                 890                 895                 900

 Leu Glu Glu Ala Val Glu Leu Val Cys Thr Ala Pro Gln Trp Val
                 905                 910                 915

 Pro Val Ser Trp Val Tyr
                 920

<210> 1647
<211> 2262
<212> DNA
<213> Homo sapien

<400> 1647
 tgagccggcc gcacgcggag gatcctaagg agcagctctg ttgcgacata 50

 ggccgagcag cgaggcccag ctccctgaaa caacagtaac ctacccctgt 100

 gggtcatcat catgccctcc gacctggcca agaagaaggc agccaaaaag 150

 aaggaggctg ccaaagctcg acagcggccc agaaaaggac atgaagaaaa 200

 tggagatgtt gtcacagaac cacaggtggc agagaagaat gaggccaatg 250

 gcagagagac cacagaagta gatttgctga ccaaggagct agaggacttt 300

 gagatgaaga aagctgctgc tcgagctgtc actggcgtcc tggcctctca 350

 ccccaacagt actgatgttc acatcatcaa cctctcactt acctttcatg 400

 gtcaagagct gctcagtgac accaaactgg aattaaactc aggccgtcgt 450

 tatggcctca ttggtttaaa tggaattgga aagtccatgc tgctctctgc 500

 tattgggaag cgtgaagtgc ccatccctga gcacatcgac atctaccatc 550

 tgactcgaga gatgccccct agtgacaaga cacccttgca ttgtgtgatg 600

 gaagtcgaca cagagcgggc catgctggag aaagaggcag agcggctggc 650

 tcatgaggat gcggagtgtg agaagctcat ggagctctac gagcgcctgg 700

 aggagctgga tgccgacaag gcagagatga gggcctcgcg gatcttgcat 750

 ggactgggtt tcacacctgc catgcagcgc aagaagctaa aagacttcag 800

 tgggggctgg aggatgaggg ttgcccttgc cagagccctc tttattcggc 850

 ccttcatgct gctcctggat gagcctacca accacctgga cctagatgct 900

 tgcgtgtggt tggaagaaga actaaaaact tttaagcgca tcttggtcct 950

 cgtctcccat tcccaggatt ttctgaatgg tgtctgtacc aatatcattc 1000

 acatgcacaa caagaaactg aagtattata cgggtaatta tgatcagtac 1050

 gtgaagacgc ggctagagct ggaggagaac cagatgaaga ggtttcactg 1100

 ggagcaagat cagattgcac acatgaagaa ctacattgcg aggtttggtc 1150

 atggcagtgc caagctggcc cggcaggccc agagcaagga gaagacgcta 1200

 cagaaaatga tggcatcagg actgacagag agggtcgtga gcgataagac 1250

 actgtcattt tatttcccac catgtggcaa gatccctcca cctgtcatta 1300

 tggtgcaaaa tgtgagcttc aagtatacaa aagatgggcc ttgcatctac 1350

 aataatctag aatttggaat tgaccttgac acacgagtgg ctctggtagg 1400

 gcccaatgga gcagggaagt caactcttct gaagctgcta actggagagc 1450

 tactacccac agatggcatg atccgaaaac actctcatgt caagataggg 1500

 cgttaccatc agcatttaca agagcagctg gacttagatc tctcaccttt 1550

 ggagtacatg atgaagtgct acccagagat caaggagaag gaagaaatga 1600

 ggaagatcat tgggcgatac ggtctcactg ggaaacaaca ggtgagccca 1650

 atccggaact tgtcagacgg gcagaagtgc cgagtgtgtc tggcctggct 1700

 ggcctggcag aacccccaca tgctcttcct ggatgaaccc accaatcacc 1750

 tggatatcga gaccatcgac gccctggcag atgccatcaa tgagtttgag 1800

 ggtggtatga tgctggtcag ccatgacttc agactcattc agcaggttgc 1850

 acaggaaatt tgggtctgtg agaagcagac aatcaccaag tggcctggag 1900

 acatcctggc ttacaaggag cacctcaagt ccaagctggt ggatgaggag 1950

 ccccagctca ccaagaggac ccacaacgtg tgcaccctga cattggcatc 2000

 tctgccaagg ccatgagcat catgaactcg tttgtaaacg acgtgtttga 2050

 gcagctggcg tgtgaggctg cccggctggc ccagtactcg ggccggacca 2100

 ccctgacatc ccgagaagtc cagacggctg tgcgtctgct gctgcctggg 2150

 gagctggcca agcacgctgt gtctgagggc accaaggctg tcaccaagta 2200

 caccagctcc aagtgaccca gggcctgaca aaaataaagg gtgaactgtt 2250

 aaaaaaaaaa aa 2262

<210> 1648
<211> 634
<212> PRT
<213> Homo sapien

<400> 1648
 Met Pro Ser Asp Leu Ala Lys Lys Lys Ala Ala Lys Lys Lys Glu
   1               5                  10                  15

 Ala Ala Lys Ala Arg Gln Arg Pro Arg Lys Gly His Glu Glu Asn
                  20                  25                  30

 Gly Asp Val Val Thr Glu Pro Gln Val Ala Glu Lys Asn Glu Ala
                  35                  40                  45

 Asn Gly Arg Glu Thr Thr Glu Val Asp Leu Leu Thr Lys Glu Leu
                  50                  55                  60

 Glu Asp Phe Glu Met Lys Lys Ala Ala Ala Arg Ala Val Thr Gly
                  65                  70                  75

 Val Leu Ala Ser His Pro Asn Ser Thr Asp Val His Ile Ile Asn
                  80                  85                  90

 Leu Ser Leu Thr Phe His Gly Gln Glu Leu Leu Ser Asp Thr Lys
                  95                 100                 105

 Leu Glu Leu Asn Ser Gly Arg Arg Tyr Gly Leu Ile Gly Leu Asn
                 110                 115                 120

 Gly Ile Gly Lys Ser Met Leu Leu Ser Ala Ile Gly Lys Arg Glu
                 125                 130                 135

 Val Pro Ile Pro Glu His Ile Asp Ile Tyr His Leu Thr Arg Glu
                 140                 145                 150

 Met Pro Pro Ser Asp Lys Thr Pro Leu His Cys Val Met Glu Val
                 155                 160                 165

 Asp Thr Glu Arg Ala Met Leu Glu Lys Glu Ala Glu Arg Leu Ala
                 170                 175                 180

 His Glu Asp Ala Glu Cys Glu Lys Leu Met Glu Leu Tyr Glu Arg
                 185                 190                 195

 Leu Glu Glu Leu Asp Ala Asp Lys Ala Glu Met Arg Ala Ser Arg
                 200                 205                 210

 Ile Leu His Gly Leu Gly Phe Thr Pro Ala Met Gln Arg Lys Lys
                 215                 220                 225

 Leu Lys Asp Phe Ser Gly Gly Trp Arg Met Arg Val Ala Leu Ala
                 230                 235                 240

 Arg Ala Leu Phe Ile Arg Pro Phe Met Leu Leu Leu Asp Glu Pro
                 245                 250                 255

 Thr Asn His Leu Asp Leu Asp Ala Cys Val Trp Leu Glu Glu Glu
                 260                 265                 270

 Leu Lys Thr Phe Lys Arg Ile Leu Val Leu Val Ser His Ser Gln
                 275                 280                 285

 Asp Phe Leu Asn Gly Val Cys Thr Asn Ile Ile His Met His Asn
                 290                 295                 300

 Lys Lys Leu Lys Tyr Tyr Thr Gly Asn Tyr Asp Gln Tyr Val Lys
                 305                 310                 315

 Thr Arg Leu Glu Leu Glu Glu Asn Gln Met Lys Arg Phe His Trp
                 320                 325                 330

 Glu Gln Asp Gln Ile Ala His Met Lys Asn Tyr Ile Ala Arg Phe
                 335                 340                 345

 Gly His Gly Ser Ala Lys Leu Ala Arg Gln Ala Gln Ser Lys Glu
                 350                 355                 360

 Lys Thr Leu Gln Lys Met Met Ala Ser Gly Leu Thr Glu Arg Val
                 365                 370                 375

 Val Ser Asp Lys Thr Leu Ser Phe Tyr Phe Pro Pro Cys Gly Lys
                 380                 385                 390

 Ile Pro Pro Pro Val Ile Met Val Gln Asn Val Ser Phe Lys Tyr
                 395                 400                 405

 Thr Lys Asp Gly Pro Cys Ile Tyr Asn Asn Leu Glu Phe Gly Ile
                 410                 415                 420

 Asp Leu Asp Thr Arg Val Ala Leu Val Gly Pro Asn Gly Ala Gly
                 425                 430                 435

 Lys Ser Thr Leu Leu Lys Leu Leu Thr Gly Glu Leu Leu Pro Thr
                 440                 445                 450

 Asp Gly Met Ile Arg Lys His Ser His Val Lys Ile Gly Arg Tyr
                 455                 460                 465

 His Gln His Leu Gln Glu Gln Leu Asp Leu Asp Leu Ser Pro Leu
                 470                 475                 480

 Glu Tyr Met Met Lys Cys Tyr Pro Glu Ile Lys Glu Lys Glu Glu
                 485                 490                 495

 Met Arg Lys Ile Ile Gly Arg Tyr Gly Leu Thr Gly Lys Gln Gln
                 500                 505                 510

 Val Ser Pro Ile Arg Asn Leu Ser Asp Gly Gln Lys Cys Arg Val
                 515                 520                 525

 Cys Leu Ala Trp Leu Ala Trp Gln Asn Pro His Met Leu Phe Leu
                 530                 535                 540

 Asp Glu Pro Thr Asn His Leu Asp Ile Glu Thr Ile Asp Ala Leu
                 545                 550                 555

 Ala Asp Ala Ile Asn Glu Phe Glu Gly Gly Met Met Leu Val Ser
                 560                 565                 570

 His Asp Phe Arg Leu Ile Gln Gln Val Ala Gln Glu Ile Trp Val
                 575                 580                 585

 Cys Glu Lys Gln Thr Ile Thr Lys Trp Pro Gly Asp Ile Leu Ala
                 590                 595                 600

 Tyr Lys Glu His Leu Lys Ser Lys Leu Val Asp Glu Glu Pro Gln
                 605                 610                 615

 Leu Thr Lys Arg Thr His Asn Val Cys Thr Leu Thr Leu Ala Ser
                 620                 625                 630

 Leu Pro Arg Pro


<210> 1649
<211> 1431
<212> DNA
<213> Homo sapien

<400> 1649
 atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc 50

 tttgacagag agcaagtctg ctcatgtgca gactcagact gggcaaattt 100

 caatccctgc tttagctcag tgcagtgagc tgagatcagg caccagaaga 150

 ggctccccag ctgtaactct agtgcagtta ccttcgggcc aaactataca 200

 tgtccaggga gtaattcaga caccacagcc atgggttatt cagtcatcag 250

 aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca 300

 gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg 350

 aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg 400

 gtgttcccaa gattgaagaa gagagatcag aggaagaagg aacaccacct 450

 agtattgcta ccatggcagt accaactagc atatatcaga ctagcacggg 500

 gcaatacatt gctatagccc aaggtggaac aatccagatt tctaacccag 550

 gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga 600

 gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga 650

 tggcacacag cagttctttg tcccaggcag ccaggttgtt gttcaagctg 700

 ccactggtga catgccaact taccagatcc gagctcctac tgctgctttg 750

 ccacagggag tggtgatggc tgcatcgccc ggaagtttgc acagtcccca 800

 gcagctggca gaagaagcaa cacgcaaacg agagctgagg ctaatgaaaa 850

 acagagaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa 900

 tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat 950

 tgaggaactc aaggccctca aagatcttta ttgccataaa gtagagtaac 1000

 tgtctttgac ttggaccttg tttactctaa tcaaggcagg agatgcagca 1050

 gtcctactta ttgccatgtg gacttgtggg aaggacacgt gtgaccctta 1100

 agaatccagt ttggattagt gtttgaaatt gaattgggaa tgttgttcca 1150

 ggatgtggaa tgcagcgtga tcacacttac cgagcttact ttgatctgtt 1200

 tgtcaatagc atgcaaaaaa tgctttgttt gccctttgct tctgcttttt 1250

 ttcagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa 1300

 atgcctggag agccgagttg cagtgctgga agtccagaac aagaagctta 1350

 tagaggaact tgaaaccttg aaagacattt gttctcccaa aactgattac 1400

 tagaaatatt taactatgaa ctgattacag a 1431

<210> 1650
<211> 332
<212> PRT
<213> Homo sapien

<400> 1650
 Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr
   1               5                  10                  15

 Ala Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr
                  20                  25                  30

 Gly Gln Ile Ser Ile Pro Ala Leu Ala Gln Cys Ser Glu Leu Arg
                  35                  40                  45

 Ser Gly Thr Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu
                  50                  55                  60

 Pro Ser Gly Gln Thr Ile His Val Gln Gly Val Ile Gln Thr Pro
                  65                  70                  75

 Gln Pro Trp Val Ile Gln Ser Ser Glu Ile His Thr Val Gln Val
                  80                  85                  90

 Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly Val
                  95                 100                 105

 Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser
                 110                 115                 120

 Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val
                 125                 130                 135

 Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro
                 140                 145                 150

 Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser
                 155                 160                 165

 Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile
                 170                 175                 180

 Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr
                 185                 190                 195

 Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val Gln
                 200                 205                 210

 Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro
                 215                 220                 225

 Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr
                 230                 235                 240

 Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val
                 245                 250                 255

 Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala
                 260                 265                 270

 Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg
                 275                 280                 285

 Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys
                 290                 295                 300

 Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr
                 305                 310                 315

 Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys
                 320                 325                 330

 Val Glu


<210> 1651
<211> 1272
<212> DNA
<213> Homo sapien

<400> 1651
 gaattcggcc aaagaggcct atgcttctct gaagacttgc agcaaggctt 50

 gctgaggctc acagaagata gccccagtgt tttggagtgg ttttgaatgt 100

 gattctgaga tcagactgac tgagctggaa tcctggcttt atatcttacc 150

 agctacacaa ccttggagtc ttagaaattt tttcttttca ataagcagtc 200

 atccttactt tccctcaaga tgacaaacag ttcgttcttc tgcccagttt 250

 ataaagatct ggagccattc acgtattttt tttatttagt tttccttgtt 300

 ggaattattg gaagttgttt tgcaacctgg gcttttatac agaagaatac 350

 gaatcacagg tgtgtgagca tctacttaat taatttgctt acagccgatt 400

 tcctgcttac tctggcatta ccagtgaaaa ttgttgttga cttgggtgtg 450

 gcaccttgga agctgaagat attccactgc caagtaacag cctgcctcat 500

 ctatatcaat atgtatttat caattatctt cttagcattt gtcagcattg 550

 accgctgtct tcagctgaca cacagctgca agatctaccg aatacaagaa 600

 cccggatttg ccaaaatgat atcaaccgtt gtgtggctaa tggtccttct 650

 tataatggtg ccaaatatga tgattcccat caaagacatc aaggaaaagt 700

 caaatgtggg ttgtatggag tttaaaaagg aatttggaag aaattggcat 750

 ttgctgacaa atttcatatg tgtagcaata tttttaaatt tctcagccat 800

 cattttaata tccaattgcc ttgtaattcg acagctctac agaaacaaag 850

 ataatgaaaa ttacccaaat gtgaaaaagg ctctcatcaa catactttta 900

 gtgaccacgg gctacatcat atgctttgtt ccttaccaca ttgtccgaat 950

 cccgtatacc ctcagccaga cagaagtcat aactgattgc tcaaccagga 1000

 tttcactctt caaagccaaa gaggctacac tgctcctggc tgtgtcgaac 1050

 ctgtgctttg atcctatcct gtactatcac ctctcaaaag cattccgctc 1100

 aaaggtcact gagacttttg cctcacctaa agagaccaag gctcagaaag 1150

 aaaaattaag atgtgaaaat aatgcataaa agacaggatt ttttgtgcta 1200

 ccaattctgg ccttactgga ccataaagtt aattatagct ttgaaagata 1250

 aaaaaaaaaa aaaagcggcc gc 1272

<210> 1652
<211> 319
<212> PRT
<213> Homo sapien

<400> 1652
 Met Thr Asn Ser Ser Phe Phe Cys Pro Val Tyr Lys Asp Leu Glu
   1               5                  10                  15

 Pro Phe Thr Tyr Phe Phe Tyr Leu Val Phe Leu Val Gly Ile Ile
                  20                  25                  30

 Gly Ser Cys Phe Ala Thr Trp Ala Phe Ile Gln Lys Asn Thr Asn
                  35                  40                  45

 His Arg Cys Val Ser Ile Tyr Leu Ile Asn Leu Leu Thr Ala Asp
                  50                  55                  60

 Phe Leu Leu Thr Leu Ala Leu Pro Val Lys Ile Val Val Asp Leu
                  65                  70                  75

 Gly Val Ala Pro Trp Lys Leu Lys Ile Phe His Cys Gln Val Thr
                  80                  85                  90

 Ala Cys Leu Ile Tyr Ile Asn Met Tyr Leu Ser Ile Ile Phe Leu
                  95                 100                 105

 Ala Phe Val Ser Ile Asp Arg Cys Leu Gln Leu Thr His Ser Cys
                 110                 115                 120

 Lys Ile Tyr Arg Ile Gln Glu Pro Gly Phe Ala Lys Met Ile Ser
                 125                 130                 135

 Thr Val Val Trp Leu Met Val Leu Leu Ile Met Val Pro Asn Met
                 140                 145                 150

 Met Ile Pro Ile Lys Asp Ile Lys Glu Lys Ser Asn Val Gly Cys
                 155                 160                 165

 Met Glu Phe Lys Lys Glu Phe Gly Arg Asn Trp His Leu Leu Thr
                 170                 175                 180

 Asn Phe Ile Cys Val Ala Ile Phe Leu Asn Phe Ser Ala Ile Ile
                 185                 190                 195

 Leu Ile Ser Asn Cys Leu Val Ile Arg Gln Leu Tyr Arg Asn Lys
                 200                 205                 210

 Asp Asn Glu Asn Tyr Pro Asn Val Lys Lys Ala Leu Ile Asn Ile
                 215                 220                 225

 Leu Leu Val Thr Thr Gly Tyr Ile Ile Cys Phe Val Pro Tyr His
                 230                 235                 240

 Ile Val Arg Ile Pro Tyr Thr Leu Ser Gln Thr Glu Val Ile Thr
                 245                 250                 255

 Asp Cys Ser Thr Arg Ile Ser Leu Phe Lys Ala Lys Glu Ala Thr
                 260                 265                 270

 Leu Leu Leu Ala Val Ser Asn Leu Cys Phe Asp Pro Ile Leu Tyr
                 275                 280                 285

 Tyr His Leu Ser Lys Ala Phe Arg Ser Lys Val Thr Glu Thr Phe
                 290                 295                 300

 Ala Ser Pro Lys Glu Thr Lys Ala Gln Lys Glu Lys Leu Arg Cys
                 305                 310                 315

 Glu Asn Asn Ala


<210> 1653
<211> 1421
<212> DNA
<213> Homo sapien

<400> 1653
 gaagcaggcc tgagcctccc caaaggcagc tcctggggac tcccaggacc 50

 acaggctgag acgagacgca gggtggctgg aggaagtgag aggtgaactc 100

 agcctgggac tggctgggcg agactctcca cctgctccct gggaccatcg 150

 cccaccatgg ctgtggccca gcagctgcgg gccgagagtg actttgaaca 200

 gcttccggat gatgttgcca tctcggccaa cattgctgac atcgaggaga 250

 agagaggctt caccagccac tttgttttcg tcatcgaggt gaagacaaaa 300

 ggaggatcca agtacctcat ctaccgccgc taccgccagt tccatgcttt 350

 gcagagcaag ctggaggagc gcttcgggcc agacagcaag agcagtgccc 400

 tggcctgtac cctgcccaca ctcccagcca aagtctacgt gggtgtgaaa 450

 caggagatcg ccgagatgcg gatacctgcc ctcaacgcct acatgaagag 500

 cctgctcagc ctgccggtct gggtgctgat ggatgaggac gtccggatct 550

 tcttttacca gtcgccctat gactcagagc aggtgcccca ggcactccgc 600

 cggctccgcc cgcgcacccg gaaagtcaag agcgtgtccc cacagggcaa 650

 cagcgttgac cgcatggcag ctccgagagc agaggctcta tttgacttca 700

 ctggaaacag caaactggag ctgaatttca aagctggaga tgtgatcttc 750

 ctcctcagtc ggatcaacaa agactggctg gagggcactg tccggggagc 800

 cacgggcatc ttccctctct ccttcgtgaa gatcctcaaa gacttccctg 850

 aggaggacga ccccaccaac tggctgcgtt gctactacta cgaagacacc 900

 atcagcacca tcaagtctgt ggcctgggag ggaggggcct gtccagcctt 950

 cctgccatcc ctacgaccac cgcccctcac atcaccttct catgggtccc 1000

 tctcccactc caaagccccc agtggctccc agatgagcca caatgctgta 1050

 acaagccatc aacgtccagg gtggcctggc cagcctcatt cccctttccc 1100

 ccaccccaca ccccacttcc agcctgatgc ctccttactc cagcctgtca 1150

 cccccttagg gacatcgcgg tggaggaaga tctcagcagc actcccctat 1200

 tgaaagacct gctggagctc acaaggcggg agttccagag agaggacata 1250

 gctctgaatt accgggacgc tgagggggat ctggttcggc tgctgtcgga 1300

 tgaggacgta gcgctcatgg tgcggcaggc tcgtggcctc ccctcccaga 1350

 agcgcctctt cccctggaag ctgcacatca cgcagaagga caactacagg 1400

 gtctacaaca cgatgccatg a 1421

<210> 1654
<211> 348
<212> PRT
<213> Homo sapien

<400> 1654
 Met Ala Val Ala Gln Gln Leu Arg Ala Glu Ser Asp Phe Glu Gln
   1               5                  10                  15

 Leu Pro Asp Asp Val Ala Ile Ser Ala Asn Ile Ala Asp Ile Glu
                  20                  25                  30

 Glu Lys Arg Gly Phe Thr Ser His Phe Val Phe Val Ile Glu Val
                  35                  40                  45

 Lys Thr Lys Gly Gly Ser Lys Tyr Leu Ile Tyr Arg Arg Tyr Arg
                  50                  55                  60

 Gln Phe His Ala Leu Gln Ser Lys Leu Glu Glu Arg Phe Gly Pro
                  65                  70                  75

 Asp Ser Lys Ser Ser Ala Leu Ala Cys Thr Leu Pro Thr Leu Pro
                  80                  85                  90

 Ala Lys Val Tyr Val Gly Val Lys Gln Glu Ile Ala Glu Met Arg
                  95                 100                 105

 Ile Pro Ala Leu Asn Ala Tyr Met Lys Ser Leu Leu Ser Leu Pro
                 110                 115                 120

 Val Trp Val Leu Met Asp Glu Asp Val Arg Ile Phe Phe Tyr Gln
                 125                 130                 135

 Ser Pro Tyr Asp Ser Glu Gln Val Pro Gln Ala Leu Arg Arg Leu
                 140                 145                 150

 Arg Pro Arg Thr Arg Lys Val Lys Ser Val Ser Pro Gln Gly Asn
                 155                 160                 165

 Ser Val Asp Arg Met Ala Ala Pro Arg Ala Glu Ala Leu Phe Asp
                 170                 175                 180

 Phe Thr Gly Asn Ser Lys Leu Glu Leu Asn Phe Lys Ala Gly Asp
                 185                 190                 195

 Val Ile Phe Leu Leu Ser Arg Ile Asn Lys Asp Trp Leu Glu Gly
                 200                 205                 210

 Thr Val Arg Gly Ala Thr Gly Ile Phe Pro Leu Ser Phe Val Lys
                 215                 220                 225

 Ile Leu Lys Asp Phe Pro Glu Glu Asp Asp Pro Thr Asn Trp Leu
                 230                 235                 240

 Arg Cys Tyr Tyr Tyr Glu Asp Thr Ile Ser Thr Ile Lys Ser Val
                 245                 250                 255

 Ala Trp Glu Gly Gly Ala Cys Pro Ala Phe Leu Pro Ser Leu Arg
                 260                 265                 270

 Pro Pro Pro Leu Thr Ser Pro Ser His Gly Ser Leu Ser His Ser
                 275                 280                 285

 Lys Ala Pro Ser Gly Ser Gln Met Ser His Asn Ala Val Thr Ser
                 290                 295                 300

 His Gln Arg Pro Gly Trp Pro Gly Gln Pro His Ser Pro Phe Pro
                 305                 310                 315

 His Pro Thr Pro His Phe Gln Pro Asp Ala Ser Leu Leu Gln Pro
                 320                 325                 330

 Val Thr Pro Leu Gly Thr Ser Arg Trp Arg Lys Ile Ser Ala Ala
                 335                 340                 345

 Leu Pro Tyr


<210> 1655
<211> 1670
<212> DNA
<213> Homo sapien

<400> 1655
 ccaaccacaa gcaccaaagc agaggggcag gcagcacacc acccagcagc 50

 cagagcacca gcccagccat ggtccttgag gtgagtgacc accaagtgct 100

 aaatgacgcc gaggttgccg ccctcctgga gaacttcagc tcttcctatg 150

 actatggaga aaacgagagt gactcgtgct gtacctcccc gccctgccca 200

 caggacttca gcctgaactt cgaccgggcc ttcctgccag ccctctacag 250

 cctcctcttt ctgctggggc tgctgggcaa cggcgcggtg gcagccgtgc 300

 tgctgagccg gcggacagcc ctgagcagca ccgacacctt cctgctccac 350

 ctagctgtag cagacacgct gctggtgctg acactgccgc tctgggcagt 400

 ggacgctgcc gtccagtggg tctttggctc tggcctctgc aaagtggcag 450

 gtgccctctt caacatcaac ttctacgcag gagccctcct gctggcctgc 500

 atcagctttg accgctacct gaacatagtt catgccaccc agctctaccg 550

 ccgggggccc ccggcccgcg tgaccctcac ctgcctggct gtctgggggc 600

 tctgcctgct tttcgccctc ccagacttca tcttcctgtc ggcccaccac 650

 gacgagcgcc tcaacgccac ccactgccaa tacaacttcc cacaggtggg 700

 ccgcacggct ctgcgggtgc tgcagctggt ggctggcttt ctgctgcccc 750

 tgctggtcat ggcctactgc tatgcccaca tcctggccgt gctgctggtt 800

 tccaggggcc agcggcgcct gcgggccatg cggctggtgg tggtggtcgt 850

 ggtggccttt gccctctgct ggacccccta tcacctggtg gtgctggtgg 900

 acatcctcat ggacctgggc gctttggccc gcaactgtgg ccgagaaagc 950

 agggtagacg tggccaagtc ggtcacctca ggcctgggct acatgcactg 1000

 ctgcctcaac ccgctgctct atgcctttgt aggggtcaag ttccgggagc 1050

 ggatgtggat gctgctcttg cgcctgggct gccccaacca gagagggctc 1100

 cagaggcagc catcgtcttc ccgccgggat tcatcctggt ctgagacctc 1150

 agaggcctcc tactcgggct tgtgaggccg gaatccgggc tcccctttcg 1200

 cccacagtct gacttccccg cattccaggc tcctccctcc ctctgccggc 1250

 tctggctctc cccaatatcc tcgctcccgg gactcactgg cagccccagc 1300

 accaccaggt ctcccgggaa gccaccctcc cagctctgag gactgcacca 1350

 ttgctgctcc ttagctgcca agccccatcc tgccgcccga ggtggctgcc 1400

 tggagcccca ctgcccttct catttggaaa ctaaaacttc atcttcccca 1450

 agtgcgggga gtacaaggca tggcgtagag ggtgctgccc catgaagcca 1500

 cagcccaggc ctccagctca gcagtgactg tggccatggt ccccaagacc 1550

 tctatatttg ctcttttatt tttatgtcta aaatcctgct taaaactttt 1600

 caataaacaa gatcgtcagg accaaaaaaa aaaaaaaaaa aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaaa 1670

<210> 1656
<211> 368
<212> PRT
<213> Homo sapien

<400> 1656
 Met Val Leu Glu Val Ser Asp His Gln Val Leu Asn Asp Ala Glu
   1               5                  10                  15

 Val Ala Ala Leu Leu Glu Asn Phe Ser Ser Ser Tyr Asp Tyr Gly
                  20                  25                  30

 Glu Asn Glu Ser Asp Ser Cys Cys Thr Ser Pro Pro Cys Pro Gln
                  35                  40                  45

 Asp Phe Ser Leu Asn Phe Asp Arg Ala Phe Leu Pro Ala Leu Tyr
                  50                  55                  60

 Ser Leu Leu Phe Leu Leu Gly Leu Leu Gly Asn Gly Ala Val Ala
                  65                  70                  75

 Ala Val Leu Leu Ser Arg Arg Thr Ala Leu Ser Ser Thr Asp Thr
                  80                  85                  90

 Phe Leu Leu His Leu Ala Val Ala Asp Thr Leu Leu Val Leu Thr
                  95                 100                 105

 Leu Pro Leu Trp Ala Val Asp Ala Ala Val Gln Trp Val Phe Gly
                 110                 115                 120

 Ser Gly Leu Cys Lys Val Ala Gly Ala Leu Phe Asn Ile Asn Phe
                 125                 130                 135

 Tyr Ala Gly Ala Leu Leu Leu Ala Cys Ile Ser Phe Asp Arg Tyr
                 140                 145                 150

 Leu Asn Ile Val His Ala Thr Gln Leu Tyr Arg Arg Gly Pro Pro
                 155                 160                 165

 Ala Arg Val Thr Leu Thr Cys Leu Ala Val Trp Gly Leu Cys Leu
                 170                 175                 180

 Leu Phe Ala Leu Pro Asp Phe Ile Phe Leu Ser Ala His His Asp
                 185                 190                 195

 Glu Arg Leu Asn Ala Thr His Cys Gln Tyr Asn Phe Pro Gln Val
                 200                 205                 210

 Gly Arg Thr Ala Leu Arg Val Leu Gln Leu Val Ala Gly Phe Leu
                 215                 220                 225

 Leu Pro Leu Leu Val Met Ala Tyr Cys Tyr Ala His Ile Leu Ala
                 230                 235                 240

 Val Leu Leu Val Ser Arg Gly Gln Arg Arg Leu Arg Ala Met Arg
                 245                 250                 255

 Leu Val Val Val Val Val Val Ala Phe Ala Leu Cys Trp Thr Pro
                 260                 265                 270

 Tyr His Leu Val Val Leu Val Asp Ile Leu Met Asp Leu Gly Ala
                 275                 280                 285

 Leu Ala Arg Asn Cys Gly Arg Glu Ser Arg Val Asp Val Ala Lys
                 290                 295                 300

 Ser Val Thr Ser Gly Leu Gly Tyr Met His Cys Cys Leu Asn Pro
                 305                 310                 315

 Leu Leu Tyr Ala Phe Val Gly Val Lys Phe Arg Glu Arg Met Trp
                 320                 325                 330

 Met Leu Leu Leu Arg Leu Gly Cys Pro Asn Gln Arg Gly Leu Gln
                 335                 340                 345

 Arg Gln Pro Ser Ser Ser Arg Arg Asp Ser Ser Trp Ser Glu Thr
                 350                 355                 360

 Ser Glu Ala Ser Tyr Ser Gly Leu
                 365

<210> 1657
<211> 2903
<212> DNA
<213> Homo sapien

<400> 1657
 tgaaggctgg ttgttcagac tgagcttcct gcctgcctgt accccgccaa 50

 cagcttcaga agaaggtgac tggtggctgc ctgaggaata ccagtgggca 100

 agagaattag catttctgga gcatctgctg tctgagcagc ccctgggtgc 150

 gtccactttc tgggcacgtg aggttgggcc ttggccgcct gagcccttga 200

 gttggtcact tgaaccttgg gaatattgag attatattct cctgcctttt 250

 aaaaagatgg acttcagcag aaatctttat gatattgggg aacaactgga 300

 cagtgaagat ctggcctccc tcaagttcct gagcctggac tacattccgc 350

 aaaggaagca agaacccatc aaggatgcct tgatgttatt ccagagactc 400

 caggaaaaga gaatgttgga ggaaagcaat ctgtccttcc tgaaggagct 450

 gctcttccga attaatagac tggatttgct gattacctac ctaaacacta 500

 gaaaggagga gatggaaagg gaacttcaga caccaggcag ggctcaaatt 550

 tctgcctaca ggttccactt ctgccgcatg agctgggctg aagcaaacag 600

 ccagtgccag acacagtctg tacctttctg gcggagggtc gatcatctat 650

 taataagggt catgctctat cagatttcag aagaagtgag cagatcagaa 700

 ttgaggtctt ttaagtttct tttgcaagag gaaatctcca aatgcaaact 750

 ggatgatgac atgaacctgc tggatatttt catagagatg gagaagaggg 800

 tcatcctggg agaaggaaag ttggacatcc tgaaaagagt ctgtgcccaa 850

 atcaacaaga gcctgctgaa gataatcaac gactatgaag aattcagcaa 900

 aggggaggag ttgtgtgggg taatgacaat ctcggactct ccaagagaac 950

 aggatagtga atcacagact ttggacaaag tttaccaaat gaaaagcaaa 1000

 cctcggggat actgtctgat catcaacaat cacaattttg caaaagcacg 1050

 ggagaaagtg cccaaacttc acagcattag ggacaggaat ggaacacact 1100

 tggatgcagg ggctttgacc acgacctttg aagagcttca ttttgagatc 1150

 aagccccacg atgactgcac agtagagcaa atctatgaga ttttgaaaat 1200

 ctaccaactc atggaccaca gtaacatgga ctgcttcatc tgctgtatcc 1250

 tctcccatgg agacaagggc atcatctatg gcactgatgg acaggaggcc 1300

 cccatctatg agctgacatc tcagttcact ggtttgaagt gcccttccct 1350

 tgctggaaaa cccaaagtgt tttttattca ggcttgtcag ggggataact 1400

 accagaaagg tatacctgtt gagactgatt cagaggagca accctattta 1450

 gaaatggatt tatcatcacc tcaaacgaga tatatcccgg atgaggctga 1500

 ctttctgctg gggatggcca ctgtgaataa ctgtgtttcc taccgaaacc 1550

 ctgcagaggg aacctggtac atccagtcac tttgccagag cctgagagag 1600

 cgatgtcctc gaggcgatga tattctcacc atcctgactg aagtgaacta 1650

 tgaagtaagc aacaaggatg acaagaaaaa catggggaaa cagatgcctc 1700

 agcctacttt cacactaaga aaaaaacttg tcttcccttc tgattgatgg 1750

 tgctattttg tttgttttgt tttgttttgt ttttttgaga cagaatctcg 1800

 ctctgtcgcc caggctggag tgcagtggcg tgatctcggc tcaccgcaag 1850

 ctccgcctcc cgggttcagg ccattctcct gcctcagcct cccgagtagc 1900

 tgggactaca ggggcccgcc accacacctg gctaattttt taaaaatatt 1950

 tttagtagag acagggtttc actgtgttag ccagggtggt cttgatctcc 2000

 tgacctcgtg atccacccac ctcggcctcc caaagtgctg ggattacagg 2050

 cgtgagccac cgcgcctggc cgatggtact atttagatat aacactatgt 2100

 ttatttacta attttctaga ttttctactt tattaattgt tttgcacttt 2150

 tttataagag ctaaagttaa ataggatatt aacaacaata acactgtctc 2200

 ctttctctta cgcttaaggc tttgggaatg tttttagctg gtggcaataa 2250

 ataccagaca cgtacaaaat ccagctatga atatagaggg cttatgattc 2300

 agattgttat ctatcaacta taagcccact gttaatattc tattaacttt 2350

 aattctcttt caaagctaaa ttccacacta ccacattaaa aaaattagaa 2400

 agtagccacg tatggtggct catgtctata atcccagcac tttgggaggt 2450

 tgaggtggga ggatttgctt gaacccaaga ggtccaaggc tgcagtgagc 2500

 catgttcaca ccgctgcact caagcttggg tgacagagca agaccccgtc 2550

 cccaaaaaaa tttttttttt aataaaccca aatttgtttg aaaactttta 2600

 aaaattcaaa tgatttttac aagttttaaa taagctctcc ccaaacttgc 2650

 tttatgcctt cttattgctt ttatgatata tatatgcttg gctaactata 2700

 tttgcttttt gctaacaatg ctctggggtc tttttatgca tttgcatttg 2750

 ctctttcatc tctgcttgga ttattttaaa tcattaggaa ttaagttatc 2800

 tttaaaattt aagtatcttt tttccaaaac attttttaat agaataaaat 2850

 ataatttgat cttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2900

 aaa 2903

<210> 1658
<211> 496
<212> PRT
<213> Homo sapien

<400> 1658
 Met Asp Phe Ser Arg Asn Leu Tyr Asp Ile Gly Glu Gln Leu Asp
   1               5                  10                  15

 Ser Glu Asp Leu Ala Ser Leu Lys Phe Leu Ser Leu Asp Tyr Ile
                  20                  25                  30

 Pro Gln Arg Lys Gln Glu Pro Ile Lys Asp Ala Leu Met Leu Phe
                  35                  40                  45

 Gln Arg Leu Gln Glu Lys Arg Met Leu Glu Glu Ser Asn Leu Ser
                  50                  55                  60

 Phe Leu Lys Glu Leu Leu Phe Arg Ile Asn Arg Leu Asp Leu Leu
                  65                  70                  75

 Ile Thr Tyr Leu Asn Thr Arg Lys Glu Glu Met Glu Arg Glu Leu
                  80                  85                  90

 Gln Thr Pro Gly Arg Ala Gln Ile Ser Ala Tyr Arg Phe His Phe
                  95                 100                 105

 Cys Arg Met Ser Trp Ala Glu Ala Asn Ser Gln Cys Gln Thr Gln
                 110                 115                 120

 Ser Val Pro Phe Trp Arg Arg Val Asp His Leu Leu Ile Arg Val
                 125                 130                 135

 Met Leu Tyr Gln Ile Ser Glu Glu Val Ser Arg Ser Glu Leu Arg
                 140                 145                 150

 Ser Phe Lys Phe Leu Leu Gln Glu Glu Ile Ser Lys Cys Lys Leu
                 155                 160                 165

 Asp Asp Asp Met Asn Leu Leu Asp Ile Phe Ile Glu Met Glu Lys
                 170                 175                 180

 Arg Val Ile Leu Gly Glu Gly Lys Leu Asp Ile Leu Lys Arg Val
                 185                 190                 195

 Cys Ala Gln Ile Asn Lys Ser Leu Leu Lys Ile Ile Asn Asp Tyr
                 200                 205                 210

 Glu Glu Phe Ser Lys Gly Glu Glu Leu Cys Gly Val Met Thr Ile
                 215                 220                 225

 Ser Asp Ser Pro Arg Glu Gln Asp Ser Glu Ser Gln Thr Leu Asp
                 230                 235                 240

 Lys Val Tyr Gln Met Lys Ser Lys Pro Arg Gly Tyr Cys Leu Ile
                 245                 250                 255

 Ile Asn Asn His Asn Phe Ala Lys Ala Arg Glu Lys Val Pro Lys
                 260                 265                 270

 Leu His Ser Ile Arg Asp Arg Asn Gly Thr His Leu Asp Ala Gly
                 275                 280                 285

 Ala Leu Thr Thr Thr Phe Glu Glu Leu His Phe Glu Ile Lys Pro
                 290                 295                 300

 His Asp Asp Cys Thr Val Glu Gln Ile Tyr Glu Ile Leu Lys Ile
                 305                 310                 315

 Tyr Gln Leu Met Asp His Ser Asn Met Asp Cys Phe Ile Cys Cys
                 320                 325                 330

 Ile Leu Ser His Gly Asp Lys Gly Ile Ile Tyr Gly Thr Asp Gly
                 335                 340                 345

 Gln Glu Ala Pro Ile Tyr Glu Leu Thr Ser Gln Phe Thr Gly Leu
                 350                 355                 360

 Lys Cys Pro Ser Leu Ala Gly Lys Pro Lys Val Phe Phe Ile Gln
                 365                 370                 375

 Ala Cys Gln Gly Asp Asn Tyr Gln Lys Gly Ile Pro Val Glu Thr
                 380                 385                 390

 Asp Ser Glu Glu Gln Pro Tyr Leu Glu Met Asp Leu Ser Ser Pro
                 395                 400                 405

 Gln Thr Arg Tyr Ile Pro Asp Glu Ala Asp Phe Leu Leu Gly Met
                 410                 415                 420

 Ala Thr Val Asn Asn Cys Val Ser Tyr Arg Asn Pro Ala Glu Gly
                 425                 430                 435

 Thr Trp Tyr Ile Gln Ser Leu Cys Gln Ser Leu Arg Glu Arg Cys
                 440                 445                 450

 Pro Arg Gly Asp Asp Ile Leu Thr Ile Leu Thr Glu Val Asn Tyr
                 455                 460                 465

 Glu Val Ser Asn Lys Asp Asp Lys Lys Asn Met Gly Lys Gln Met
                 470                 475                 480

 Pro Gln Pro Thr Phe Thr Leu Arg Lys Lys Leu Val Phe Pro Ser
                 485                 490                 495

 Asp


<210> 1659
<211> 2081
<212> DNA
<213> Homo sapien

<400> 1659
 cccgggtgta cgtgtaaaat tatgatcaaa taaatttgta tgccttttct 50

 cctattaacc tgcctttttt gtcagcgatt gtcagtgaaa cttcagaggg 100

 caaaggggaa gttttccttg gcccctccag ttttggtgct gtgaacagga 150

 taccaaagct gctctgttct tctggaagct gcaatgaagg gaaccaagga 200

 cctgacaagc cagcagaagg agtctaacgt gaagacattt tgctccaaga 250

 atatcctagc catccttggc ttctcctcta tcatagctgt gatagctttg 300

 cttgctgtgg ggttgaccca gaacaaagca ttgccagaaa acgttaagta 350

 tgggattgtg ctggatgcgg gttcttctca cacaagttta tacatctata 400

 agtggccagc agaaaaggag aatgacacag gcgtggtgca tcaagtagaa 450

 gaatgcaggg ttaaaggtcc tggaatctca aaatttgttc agaaagtaaa 500

 tgaaataggc atttacctga ctgattgcat ggaaagagct agggaagtga 550

 ttccaaggtc ccagcaccaa gagacacccg tttacctggg agccacggca 600

 ggcatgcggt tgctcaggat ggaaagtgaa gagttggcag acagggttct 650

 ggatgtggtg gagaggagcc tcagcaacta cccctttgac ttccagggtg 700

 ccaggatcat tactggccaa gaggaaggtg cctatggctg gattactatc 750

 aactatctgc tgggcaaatt cagtcagaaa acaaggtggt tcagcatagt 800

 cccatatgaa accaataatc aggaaacctt tggagctttg gaccttgggg 850

 gagcctctac acaagtcact tttgtacccc aaaaccagac tatcgagtcc 900

 ccagataatg ctctgcaatt tcgcctctat ggcaaggact acaatgtcta 950

 cacacatagc ttcttgtgct atgggaagga tcaggcactc tggcagaaac 1000

 tggccaagga cattcaggtt gcaagtaatg aaattctcag ggacccatgc 1050

 tttcatcctg gatataagaa ggtagtgaac gtaagtgacc tttacaagac 1100

 cccctgcacc aagagatttg agatgactct tccattccag cagtttgaaa 1150

 tccagggtat tggaaactat caacaatgcc atcaaagcat cctggagctc 1200

 ttcaacacca gttactgccc ttactcccag tgtgccttca atgggatttt 1250

 cttgccacca ctccaggggg attttggggc attttcagct ttttactttg 1300

 tgatgaagtt tttaaacttg acatcagaga aagtctctca ggaaaaggtg 1350

 actgagatga tgaaaaagtt ctgtgctcag ccttgggagg agataaaaac 1400

 atcttacgct ggagtaaagg agaagtacct gagtgaatac tgcttttctg 1450

 gtacctacat tctctccctc cttctgcaag gctatcattt cacagctgat 1500

 tcctgggagc acatccattt cattggcaag atccagggca gcgacgccgg 1550

 ctggactttg ggctacatgc tgaacctgac caacatgatc ccagctgagc 1600

 aaccattgtc cacacctctc tcccactcca cctatgtctt cctcatggtt 1650

 ctattctccc tggtcctttt cacagtggcc atcataggct tgcttatctt 1700

 tcacaagcct tcatatttct ggaaagatat ggtatagcaa aagcagctga 1750

 aatatgctgg ctggagtgag gaaaaaatcg tccagggagc attttcctcc 1800

 atcgcagtgt tcaaggccat ccttccctgt ctgccagggc cagtcttgac 1850

 gagtgtgaag cttccttggc ttttactgaa gcctttcttt tggaggtatt 1900

 caatatcctt tgcctcaagg acttcggcag atactgtctc tttcatgagt 1950

 ttttcccagc tacacctttc tcctttgtac tttgtgcttg tataggtttt 2000

 aaagacctga cacctttcat aatctttgct ttataaaaga acaatattga 2050

 ctttgtctag aaaaaaaaaa aaaaaaaaaa a 2081

<210> 1660
<211> 517
<212> PRT
<213> Homo sapien

<400> 1660
 Met Lys Gly Thr Lys Asp Leu Thr Ser Gln Gln Lys Glu Ser Asn
   1               5                  10                  15

 Val Lys Thr Phe Cys Ser Lys Asn Ile Leu Ala Ile Leu Gly Phe
                  20                  25                  30

 Ser Ser Ile Ile Ala Val Ile Ala Leu Leu Ala Val Gly Leu Thr
                  35                  40                  45

 Gln Asn Lys Ala Leu Pro Glu Asn Val Lys Tyr Gly Ile Val Leu
                  50                  55                  60

 Asp Ala Gly Ser Ser His Thr Ser Leu Tyr Ile Tyr Lys Trp Pro
                  65                  70                  75

 Ala Glu Lys Glu Asn Asp Thr Gly Val Val His Gln Val Glu Glu
                  80                  85                  90

 Cys Arg Val Lys Gly Pro Gly Ile Ser Lys Phe Val Gln Lys Val
                  95                 100                 105

 Asn Glu Ile Gly Ile Tyr Leu Thr Asp Cys Met Glu Arg Ala Arg
                 110                 115                 120

 Glu Val Ile Pro Arg Ser Gln His Gln Glu Thr Pro Val Tyr Leu
                 125                 130                 135

 Gly Ala Thr Ala Gly Met Arg Leu Leu Arg Met Glu Ser Glu Glu
                 140                 145                 150

 Leu Ala Asp Arg Val Leu Asp Val Val Glu Arg Ser Leu Ser Asn
                 155                 160                 165

 Tyr Pro Phe Asp Phe Gln Gly Ala Arg Ile Ile Thr Gly Gln Glu
                 170                 175                 180

 Glu Gly Ala Tyr Gly Trp Ile Thr Ile Asn Tyr Leu Leu Gly Lys
                 185                 190                 195

 Phe Ser Gln Lys Thr Arg Trp Phe Ser Ile Val Pro Tyr Glu Thr
                 200                 205                 210

 Asn Asn Gln Glu Thr Phe Gly Ala Leu Asp Leu Gly Gly Ala Ser
                 215                 220                 225

 Thr Gln Val Thr Phe Val Pro Gln Asn Gln Thr Ile Glu Ser Pro
                 230                 235                 240

 Asp Asn Ala Leu Gln Phe Arg Leu Tyr Gly Lys Asp Tyr Asn Val
                 245                 250                 255

 Tyr Thr His Ser Phe Leu Cys Tyr Gly Lys Asp Gln Ala Leu Trp
                 260                 265                 270

 Gln Lys Leu Ala Lys Asp Ile Gln Val Ala Ser Asn Glu Ile Leu
                 275                 280                 285

 Arg Asp Pro Cys Phe His Pro Gly Tyr Lys Lys Val Val Asn Val
                 290                 295                 300

 Ser Asp Leu Tyr Lys Thr Pro Cys Thr Lys Arg Phe Glu Met Thr
                 305                 310                 315

 Leu Pro Phe Gln Gln Phe Glu Ile Gln Gly Ile Gly Asn Tyr Gln
                 320                 325                 330

 Gln Cys His Gln Ser Ile Leu Glu Leu Phe Asn Thr Ser Tyr Cys
                 335                 340                 345

 Pro Tyr Ser Gln Cys Ala Phe Asn Gly Ile Phe Leu Pro Pro Leu
                 350                 355                 360

 Gln Gly Asp Phe Gly Ala Phe Ser Ala Phe Tyr Phe Val Met Lys
                 365                 370                 375

 Phe Leu Asn Leu Thr Ser Glu Lys Val Ser Gln Glu Lys Val Thr
                 380                 385                 390

 Glu Met Met Lys Lys Phe Cys Ala Gln Pro Trp Glu Glu Ile Lys
                 395                 400                 405

 Thr Ser Tyr Ala Gly Val Lys Glu Lys Tyr Leu Ser Glu Tyr Cys
                 410                 415                 420

 Phe Ser Gly Thr Tyr Ile Leu Ser Leu Leu Leu Gln Gly Tyr His
                 425                 430                 435

 Phe Thr Ala Asp Ser Trp Glu His Ile His Phe Ile Gly Lys Ile
                 440                 445                 450

 Gln Gly Ser Asp Ala Gly Trp Thr Leu Gly Tyr Met Leu Asn Leu
                 455                 460                 465

 Thr Asn Met Ile Pro Ala Glu Gln Pro Leu Ser Thr Pro Leu Ser
                 470                 475                 480

 His Ser Thr Tyr Val Phe Leu Met Val Leu Phe Ser Leu Val Leu
                 485                 490                 495

 Phe Thr Val Ala Ile Ile Gly Leu Leu Ile Phe His Lys Pro Ser
                 500                 505                 510

 Tyr Phe Trp Lys Asp Met Val
                 515

<210> 1661
<211> 6754
<212> DNA
<213> Homo sapien

<400> 1661
 gtcgacgtgg cggccggcgg cggctgcggg ctgagcggcg agtttccgat 50

 ttaaagctga gctgcgagga aaatggcggc gggaggatca aaatacttgc 100

 tggatggtgg actcagagac caataaaaat aaactgcttg aacatccttt 150

 gactggttag ccagttgctg atgtatattc aagatgagtg gattaggaga 200

 aaacttggat ccactggcca gtgattcacg aaaacgcaaa ttgccatgtg 250

 atactccagg acaaggtctt acctgcagtg gtgaaaaacg gagacgggag 300

 caggaaagta aatatattga agaattggct gagctgatat ctgccaatct 350

 tagtgatatt gacaatttca atgtcaaacc agataaatgt gcgattttaa 400

 aggaaacagt aagacagata cgtcaaataa aagagcaagg aaaaactatt 450

 tccaatgatg atgatgttca aaaagccgat gtatcttcta cagggcaggg 500

 agttattgat aaagactcct taggaccgct tttacttcag gcattggatg 550

 gtttcctatt tgtggtgaat cgagacggaa acattgtatt tgtatcagaa 600

 aatgtcacac aatacctgca atataagcaa gaggacctgg ttaacacaag 650

 tgtttacaat atcttacatg aagaagacag aaaggatttt cttaagaatt 700

 taccaaaatc tacagttaat ggagtttcct ggacaaatga gacccaaaga 750

 caaaaaagcc atacatttaa ttgccgtatg ttgatgaaaa caccacatga 800

 tattctggaa gacataaacg ccagtcctga aatgcgccag agatatgaaa 850

 caatgcagtg ctttgccctg tctcagccac gagctatgat ggaggaaggg 900

 gaagatttgc aatcttgtat gatctgtgtg gcacgccgca ttactacagg 950

 agaaagaaca tttccatcaa accctgagag ctttattacc agacatgatc 1000

 tttcaggaaa ggttgtcaat atagatacaa attcactgag atcctccatg 1050

 aggcctggct ttgaagatat aatccgaagg tgtattcaga gattttttag 1100

 tctaaatgat gggcagtcat ggtcccagaa acgtcactat caagaagtta 1150

 ccagtgatgg gatattttcc ccaacagctt atcttaatgg ccatgcagaa 1200

 accccagtat atcgattctc gttggctgat ggaactatag tgactgcaca 1250

 gacaaaaagc aaactcttcc gaaatcctgt aacaaatgat cgacatggct 1300

 ttgtctcaac ccacttcctt cagagagaac agaatggata tagaccaaac 1350

 ccaaatcctg ttggacaagg gattagacca cctatggctg gatgcaacag 1400

 ttcggtaggc ggcatgagta tgtcgccaaa ccaaggctta cagatgccga 1450

 gcagcagggc ctatggcttg gcagacccta gcaccacagg gcagatgagt 1500

 ggagctaggt atgggggttc cagtaacata gcttcattga cccctgggcc 1550

 aggcatgcaa tcaccatctt cctaccagaa caacaactat aggctcaaca 1600

 tgagtagccc cccacatggg agtcctggtc ttgccccaaa ccagcagaat 1650

 atcatgattt ctcctcgtaa tcgtgggagt ccaaagatag cctcacatca 1700

 gttttctcct gttgcaggtg tgcactctcc catggcatct tctggcaata 1750

 ctgggaacca cagcttttcc agcagctctc tcagtgccct gcaagccatc 1800

 agtgaaggtg tggggacttc ccttttatct actctgtcat caccaggccc 1850

 caaattggat aactctccca atatgaatat tacccaacca agtaaagtaa 1900

 gcaatcagga ttccaagagt cctctgggct tttattgcga ccaaaatcca 1950

 gtggagagtt caatgtgtca gtcaaatagc agagatcacc tcagtgacaa 2000

 agaaagtaag gagagcagtg ttgagggggc agagaatcaa aggggtcctt 2050

 tggaaagcaa aggtcataaa aaattactgc agttacttac ctgttcttct 2100

 gatgaccggg gtcattcctc cttgaccaac tcccccctag attcaagttg 2150

 taaagaatct tctgttagtg tcaccagccc ctctggagtc tcctcctcta 2200

 catctggagg agtatcctct acatccaata tgcatgggtc actgttacaa 2250

 gagaagcacc ggattttgca caagttgctg cagaatggga attcaccagc 2300

 tgaggtagcc aagattactg cagaagccac tgggaaagac accagcagta 2350

 taacttcttg tggggacgga aatgttgtca agcaggagca gctaagtcct 2400

 aagaagaagg agaataatgc acttcttaga tacctgctgg acagggatga 2450

 tcctagtgat gcactctcta aagaactaca gccccaagtg gaaggagtgg 2500

 ataataaaat gagtcagtgc accagctcca ccattcctag ctcaagtcaa 2550

 gagaaagacc ctaaaattaa gacagagaca agtgaagagg gatctggaga 2600

 cttggataat ctagatgcta ttcttggtga tctgactagt tctgactttt 2650

 acaataattc catatcctca aatggtagtc atctggggac taagcaacag 2700

 gtgtttcaag gaactaattc tctgggtttg aaaagttcac agtctgtgca 2750

 gtctattcgt cctccatata accgagcagt gtctctggat agccctgttt 2800

 ctgttggctc aagtcctcca gtaaaaaata tcagtgcttt ccccatgtta 2850

 ccaaagcaac ccatgttggg tgggaatcca agaatgatgg atagtcagga 2900

 aaattatggc tcaagtatgg gagactgggg cttaccaaac tcaaaggccg 2950

 gcagaatgga acctatgaat tcaaactcca tgggaagacc aggaggagat 3000

 tataatactt ctttacccag acctgcactg ggtggctcta ttcccacatt 3050

 gcctcttcgg tctaatagca taccaggtgc gagaccagta ttgcaacagc 3100

 agcagcagat gcttcaaatg aggcctggtg aaatccccat gggaatgggg 3150

 gctaatccct atggccaagc agcagcatct aaccaactgg gttcctggcc 3200

 cgatggcatg ttgtccatgg aacaagtttc tcatggcact caaaataggc 3250

 ctcttcttag gaattccctg gatgatcttg ttgggccacc ttccaacctg 3300

 gaaggccaga gtgacgaaag agcattattg gaccagctgc acactcttct 3350

 cagcaacaca gatgccacag gcctggaaga aattgacaga gctttgggca 3400

 ttcctgaact tgtcaatcag ggacaggcat tagagcccaa acaggatgct 3450

 ttccaaggcc aagaagcagc agtaatgatg gatcagaagg caggattata 3500

 tggacagaca tacccagcac aggggcctcc aatgcaagga ggctttcatc 3550

 ttcagggaca atcaccatct tttaactcta tgatgaatca gatgaaccag 3600

 caaggcaatt ttcctctcca aggaatgcac ccacgagcca acatcatgag 3650

 accccggaca aacaccccca agcaacttag aatgcagctt cagcagaggc 3700

 tgcagggcca gcagtttttg aatcagagcc gacaggcact tgaattgaaa 3750

 atggaaaacc ctactgctgg tggtgctgcg gtgatgaggc ctatgatgca 3800

 gccccagcag ggttttctta atgctcaaat ggtcgcccaa cgcagcagag 3850

 agctgctaag tcatcacttc cgacaacaga gggtggctat gatgatgcag 3900

 cagcagcaac agcagcagca gcagcagcag cagcagcaac agcaacagca 3950

 acagcaacag cagcaacagc agcaaaccca ggccttcagc ccacctccta 4000

 atgtgactgc ttcccccagc atggatgggc ttttggcagg acccacaatg 4050

 ccacaagctc ctccgcaaca gtttccatat caaccaaatt atggaatggg 4100

 acaacaacca gatccagcct ttggtcgagt gtctagtcct cccaatgcaa 4150

 tgatgtcgtc aagaatgggt ccctcccaga atcccatgat gcaacacccg 4200

 caggctgcat ccatctatca gtcctcagaa atgaagggct ggccatcagg 4250

 aaatttggcc aggaacagct ccttttccca gcagcagttt gcccaccagg 4300

 ggaatcctgc agtgtatagt atggtgcaca tgaatggcag cagtggtcac 4350

 atgggacaga tgaacatgaa ccccatgccc atgtctggca tgcctatggg 4400

 tcctgatcag aaatactgct gacatctctg caccaggacc tcttaaggaa 4450

 accactgtac aaatgacact gcactaggat tattgggaag gaatcattgt 4500

 tccaggcatc catcttggaa gaaaggacca gctttgagct ccatcaaggg 4550

 tattttaagt gatgtcattt gagcaggact ggattttaag ccgaagggca 4600

 atatctacgt gtttttcccc cctccttctg ctgtgtatca tggtgttcaa 4650

 aacagaaatg ttttttggca ttccacctcc tagggatata attctggaga 4700

 catggagtgt tactgatcat aaaacttttg tgtcactttt ttctgccttg 4750

 ctagccaaaa tctcttaaat acacgtaggt gggccagaga acattggaag 4800

 aatcaagaga gattagaata tctggtttct ctagttgcag tattggacaa 4850

 agagcatagt cccagccttc aggtgtagta gttctgtgtt gaccctttgt 4900

 ccagtggaat tggtgattct gaattgtcct ttactaatgg tgttgagttg 4950

 ctctgtccct attatttgcc ctaggctttc tcctaatgaa ggttttcatt 5000

 tgccattcat gtcctgtaat acttcacctc caggaactgt catggatgtc 5050

 caaatggctt tgcagaaagg aaatgagatg acagtattta atcgcagcag 5100

 tagcaaactt ttcacatgct aatgtgcagc tgagtgcact ttatttaaaa 5150

 agaatggata aatgcaatat tcttgaggtc ttgagggaat agtgaaacac 5200

 attcctggtt tttgcctaca cttacgtgtt agacaagaac tatgattttt 5250

 ttttttaaag tactggtgtc accctttgcc tatatggtag agcaataatg 5300

 ctttttaaaa ataaacttct gaaaacccaa ggccaggtac tgcattctga 5350

 atcagaatct cgcagtgttt ctgtgaatag atttttttgt aaatatgacc 5400

 tttaagatat tgtattatgt aaaatatgta tatacctttt tttgtaggtc 5450

 acaacaactc atttttacag agtttgtgaa gctaaatatt taacattgtt 5500

 gatttcagta agctgtgtgg tgaggctacc agtggaagag acatcccttg 5550

 acttttgtgg cctgggggag gggtagtgca ccacagcttt tccttcccca 5600

 ccccccagcc ttagatgcct cgctcttttc aatctcttaa tctaaatgct 5650

 ttttaaagag attatttgtt tagatgtagg cattttaatt ttttaaaaat 5700

 tcctctacca gaactaagca ctttgttaat ttggggggaa agaatagata 5750

 tggggaaata aacttaaaaa aaaatcagga atttaaaaaa aacgagcaat 5800

 ttgaagagaa tcttttggat tttaagcagt ccgaaataat agcaattcat 5850

 gggctgtgtg tgtgtgtgta tgtgtgtgtg tgtgtgtgta tgtttaatta 5900

 tgttaccttt tcatcccctt taggagcgtt ttcagatttt ggttcgtaag 5950

 acctgaatcc catattgaga tctcgagtag aatccttggt gtggtttctg 6000

 gtgtctgctc agctgtcccc tcattctact aatgtgatgc tttcattatg 6050

 tccctgtgga ttagaatagt gtcagttatt tcttaagtaa ctcagtaccc 6100

 agaacagcca gttttactgt gattcagagc cacagtctaa ctgagcacct 6150

 tttaaacccc tccctcttct gccccctacc acttttctgc tgttgcctct 6200

 ctttgacacc tgttttagtc agttgggagg aagggaaaaa tcaagtttaa 6250

 ttccctttat ctgggttaat tcatttggtt caaatagttg acggaattgg 6300

 gtttctgaat gtctgtgaat ttcagaggtc tctgctagcc ttggtatcat 6350

 tttctagcaa taactgagag ccagttaatt ttaagaattt cacacattta 6400

 gccaatcttt ctagatgtct ctgaaggtaa gatcatttaa tatctttgat 6450

 atgcttacga gtaagtgaat cctgattatt tccagaccca ccaccagagt 6500

 ggatcttatt ttcaaagcag tatagacaat tatgagtttg ccctctttcc 6550

 cctaccaagt tcaaaatata tctaagaaag attgtaaatc cgaaaacttc 6600

 cattgtagtg gcctgtgctt ttcagatagt atactctcct gtttggagac 6650

 agaggaagaa ccaggtcagt ctgtctcttt ttcagctcaa ttgtatctga 6700

 cccttcttta agttatgtgt gtggggagaa atagaatggt gctcttatgt 6750

 cgac 6754

<210> 1662
<211> 1412
<212> PRT
<213> Homo sapien

<400> 1662
 Met Ser Gly Leu Gly Glu Asn Leu Asp Pro Leu Ala Ser Asp Ser
   1               5                  10                  15

 Arg Lys Arg Lys Leu Pro Cys Asp Thr Pro Gly Gln Gly Leu Thr
                  20                  25                  30

 Cys Ser Gly Glu Lys Arg Arg Arg Glu Gln Glu Ser Lys Tyr Ile
                  35                  40                  45

 Glu Glu Leu Ala Glu Leu Ile Ser Ala Asn Leu Ser Asp Ile Asp
                  50                  55                  60

 Asn Phe Asn Val Lys Pro Asp Lys Cys Ala Ile Leu Lys Glu Thr
                  65                  70                  75

 Val Arg Gln Ile Arg Gln Ile Lys Glu Gln Gly Lys Thr Ile Ser
                  80                  85                  90

 Asn Asp Asp Asp Val Gln Lys Ala Asp Val Ser Ser Thr Gly Gln
                  95                 100                 105

 Gly Val Ile Asp Lys Asp Ser Leu Gly Pro Leu Leu Leu Gln Ala
                 110                 115                 120

 Leu Asp Gly Phe Leu Phe Val Val Asn Arg Asp Gly Asn Ile Val
                 125                 130                 135

 Phe Val Ser Glu Asn Val Thr Gln Tyr Leu Gln Tyr Lys Gln Glu
                 140                 145                 150

 Asp Leu Val Asn Thr Ser Val Tyr Asn Ile Leu His Glu Glu Asp
                 155                 160                 165

 Arg Lys Asp Phe Leu Lys Asn Leu Pro Lys Ser Thr Val Asn Gly
                 170                 175                 180

 Val Ser Trp Thr Asn Glu Thr Gln Arg Gln Lys Ser His Thr Phe
                 185                 190                 195

 Asn Cys Arg Met Leu Met Lys Thr Pro His Asp Ile Leu Glu Asp
                 200                 205                 210

 Ile Asn Ala Ser Pro Glu Met Arg Gln Arg Tyr Glu Thr Met Gln
                 215                 220                 225

 Cys Phe Ala Leu Ser Gln Pro Arg Ala Met Met Glu Glu Gly Glu
                 230                 235                 240

 Asp Leu Gln Ser Cys Met Ile Cys Val Ala Arg Arg Ile Thr Thr
                 245                 250                 255

 Gly Glu Arg Thr Phe Pro Ser Asn Pro Glu Ser Phe Ile Thr Arg
                 260                 265                 270

 His Asp Leu Ser Gly Lys Val Val Asn Ile Asp Thr Asn Ser Leu
                 275                 280                 285

 Arg Ser Ser Met Arg Pro Gly Phe Glu Asp Ile Ile Arg Arg Cys
                 290                 295                 300

 Ile Gln Arg Phe Phe Ser Leu Asn Asp Gly Gln Ser Trp Ser Gln
                 305                 310                 315

 Lys Arg His Tyr Gln Glu Val Thr Ser Asp Gly Ile Phe Ser Pro
                 320                 325                 330

 Thr Ala Tyr Leu Asn Gly His Ala Glu Thr Pro Val Tyr Arg Phe
                 335                 340                 345

 Ser Leu Ala Asp Gly Thr Ile Val Thr Ala Gln Thr Lys Ser Lys
                 350                 355                 360

 Leu Phe Arg Asn Pro Val Thr Asn Asp Arg His Gly Phe Val Ser
                 365                 370                 375

 Thr His Phe Leu Gln Arg Glu Gln Asn Gly Tyr Arg Pro Asn Pro
                 380                 385                 390

 Asn Pro Val Gly Gln Gly Ile Arg Pro Pro Met Ala Gly Cys Asn
                 395                 400                 405

 Ser Ser Val Gly Gly Met Ser Met Ser Pro Asn Gln Gly Leu Gln
                 410                 415                 420

 Met Pro Ser Ser Arg Ala Tyr Gly Leu Ala Asp Pro Ser Thr Thr
                 425                 430                 435

 Gly Gln Met Ser Gly Ala Arg Tyr Gly Gly Ser Ser Asn Ile Ala
                 440                 445                 450

 Ser Leu Thr Pro Gly Pro Gly Met Gln Ser Pro Ser Ser Tyr Gln
                 455                 460                 465

 Asn Asn Asn Tyr Arg Leu Asn Met Ser Ser Pro Pro His Gly Ser
                 470                 475                 480

 Pro Gly Leu Ala Pro Asn Gln Gln Asn Ile Met Ile Ser Pro Arg
                 485                 490                 495

 Asn Arg Gly Ser Pro Lys Ile Ala Ser His Gln Phe Ser Pro Val
                 500                 505                 510

 Ala Gly Val His Ser Pro Met Ala Ser Ser Gly Asn Thr Gly Asn
                 515                 520                 525

 His Ser Phe Ser Ser Ser Ser Leu Ser Ala Leu Gln Ala Ile Ser
                 530                 535                 540

 Glu Gly Val Gly Thr Ser Leu Leu Ser Thr Leu Ser Ser Pro Gly
                 545                 550                 555

 Pro Lys Leu Asp Asn Ser Pro Asn Met Asn Ile Thr Gln Pro Ser
                 560                 565                 570

 Lys Val Ser Asn Gln Asp Ser Lys Ser Pro Leu Gly Phe Tyr Cys
                 575                 580                 585

 Asp Gln Asn Pro Val Glu Ser Ser Met Cys Gln Ser Asn Ser Arg
                 590                 595                 600

 Asp His Leu Ser Asp Lys Glu Ser Lys Glu Ser Ser Val Glu Gly
                 605                 610                 615

 Ala Glu Asn Gln Arg Gly Pro Leu Glu Ser Lys Gly His Lys Lys
                 620                 625                 630

 Leu Leu Gln Leu Leu Thr Cys Ser Ser Asp Asp Arg Gly His Ser
                 635                 640                 645

 Ser Leu Thr Asn Ser Pro Leu Asp Ser Ser Cys Lys Glu Ser Ser
                 650                 655                 660

 Val Ser Val Thr Ser Pro Ser Gly Val Ser Ser Ser Thr Ser Gly
                 665                 670                 675

 Gly Val Ser Ser Thr Ser Asn Met His Gly Ser Leu Leu Gln Glu
                 680                 685                 690

 Lys His Arg Ile Leu His Lys Leu Leu Gln Asn Gly Asn Ser Pro
                 695                 700                 705

 Ala Glu Val Ala Lys Ile Thr Ala Glu Ala Thr Gly Lys Asp Thr
                 710                 715                 720

 Ser Ser Ile Thr Ser Cys Gly Asp Gly Asn Val Val Lys Gln Glu
                 725                 730                 735

 Gln Leu Ser Pro Lys Lys Lys Glu Asn Asn Ala Leu Leu Arg Tyr
                 740                 745                 750

 Leu Leu Asp Arg Asp Asp Pro Ser Asp Ala Leu Ser Lys Glu Leu
                 755                 760                 765

 Gln Pro Gln Val Glu Gly Val Asp Asn Lys Met Ser Gln Cys Thr
                 770                 775                 780

 Ser Ser Thr Ile Pro Ser Ser Ser Gln Glu Lys Asp Pro Lys Ile
                 785                 790                 795

 Lys Thr Glu Thr Ser Glu Glu Gly Ser Gly Asp Leu Asp Asn Leu
                 800                 805                 810

 Asp Ala Ile Leu Gly Asp Leu Thr Ser Ser Asp Phe Tyr Asn Asn
                 815                 820                 825

 Ser Ile Ser Ser Asn Gly Ser His Leu Gly Thr Lys Gln Gln Val
                 830                 835                 840

 Phe Gln Gly Thr Asn Ser Leu Gly Leu Lys Ser Ser Gln Ser Val
                 845                 850                 855

 Gln Ser Ile Arg Pro Pro Tyr Asn Arg Ala Val Ser Leu Asp Ser
                 860                 865                 870

 Pro Val Ser Val Gly Ser Ser Pro Pro Val Lys Asn Ile Ser Ala
                 875                 880                 885

 Phe Pro Met Leu Pro Lys Gln Pro Met Leu Gly Gly Asn Pro Arg
                 890                 895                 900

 Met Met Asp Ser Gln Glu Asn Tyr Gly Ser Ser Met Gly Asp Trp
                 905                 910                 915

 Gly Leu Pro Asn Ser Lys Ala Gly Arg Met Glu Pro Met Asn Ser
                 920                 925                 930

 Asn Ser Met Gly Arg Pro Gly Gly Asp Tyr Asn Thr Ser Leu Pro
                 935                 940                 945

 Arg Pro Ala Leu Gly Gly Ser Ile Pro Thr Leu Pro Leu Arg Ser
                 950                 955                 960

 Asn Ser Ile Pro Gly Ala Arg Pro Val Leu Gln Gln Gln Gln Gln
                 965                 970                 975

 Met Leu Gln Met Arg Pro Gly Glu Ile Pro Met Gly Met Gly Ala
                 980                 985                 990

 Asn Pro Tyr Gly Gln Ala Ala Ala Ser Asn Gln Leu Gly Ser Trp
                 995                1000                1005

 Pro Asp Gly Met Leu Ser Met Glu Gln Val Ser His Gly Thr Gln
                1010                1015                1020

 Asn Arg Pro Leu Leu Arg Asn Ser Leu Asp Asp Leu Val Gly Pro
                1025                1030                1035

 Pro Ser Asn Leu Glu Gly Gln Ser Asp Glu Arg Ala Leu Leu Asp
                1040                1045                1050

 Gln Leu His Thr Leu Leu Ser Asn Thr Asp Ala Thr Gly Leu Glu
                1055                1060                1065

 Glu Ile Asp Arg Ala Leu Gly Ile Pro Glu Leu Val Asn Gln Gly
                1070                1075                1080

 Gln Ala Leu Glu Pro Lys Gln Asp Ala Phe Gln Gly Gln Glu Ala
                1085                1090                1095

 Ala Val Met Met Asp Gln Lys Ala Gly Leu Tyr Gly Gln Thr Tyr
                1100                1105                1110

 Pro Ala Gln Gly Pro Pro Met Gln Gly Gly Phe His Leu Gln Gly
                1115                1120                1125

 Gln Ser Pro Ser Phe Asn Ser Met Met Asn Gln Met Asn Gln Gln
                1130                1135                1140

 Gly Asn Phe Pro Leu Gln Gly Met His Pro Arg Ala Asn Ile Met
                1145                1150                1155

 Arg Pro Arg Thr Asn Thr Pro Lys Gln Leu Arg Met Gln Leu Gln
                1160                1165                1170

 Gln Arg Leu Gln Gly Gln Gln Phe Leu Asn Gln Ser Arg Gln Ala
                1175                1180                1185

 Leu Glu Leu Lys Met Glu Asn Pro Thr Ala Gly Gly Ala Ala Val
                1190                1195                1200

 Met Arg Pro Met Met Gln Pro Gln Gln Gly Phe Leu Asn Ala Gln
                1205                1210                1215

 Met Val Ala Gln Arg Ser Arg Glu Leu Leu Ser His His Phe Arg
                1220                1225                1230

 Gln Gln Arg Val Ala Met Met Met Gln Gln Gln Gln Gln Gln Gln
                1235                1240                1245

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                1250                1255                1260

 Gln Gln Gln Gln Thr Gln Ala Phe Ser Pro Pro Pro Asn Val Thr
                1265                1270                1275

 Ala Ser Pro Ser Met Asp Gly Leu Leu Ala Gly Pro Thr Met Pro
                1280                1285                1290

 Gln Ala Pro Pro Gln Gln Phe Pro Tyr Gln Pro Asn Tyr Gly Met
                1295                1300                1305

 Gly Gln Gln Pro Asp Pro Ala Phe Gly Arg Val Ser Ser Pro Pro
                1310                1315                1320

 Asn Ala Met Met Ser Ser Arg Met Gly Pro Ser Gln Asn Pro Met
                1325                1330                1335

 Met Gln His Pro Gln Ala Ala Ser Ile Tyr Gln Ser Ser Glu Met
                1340                1345                1350

 Lys Gly Trp Pro Ser Gly Asn Leu Ala Arg Asn Ser Ser Phe Ser
                1355                1360                1365

 Gln Gln Gln Phe Ala His Gln Gly Asn Pro Ala Val Tyr Ser Met
                1370                1375                1380

 Val His Met Asn Gly Ser Ser Gly His Met Gly Gln Met Asn Met
                1385                1390                1395

 Asn Pro Met Pro Met Ser Gly Met Pro Met Gly Pro Asp Gln Lys
                1400                1405                1410

 Tyr Cys


<210> 1663
<211> 798
<212> DNA
<213> Homo sapien

<400> 1663
 atgaataaac aaagaggaac cttctcagaa gtgagtctgg cccaggaccc 50

 aaagccgcag caaaggaaac ctaaaggcaa taaaagctcc atttcaggaa 100

 ccgaacagga aatattccaa gtagaattaa accttcaaaa tgcttctctg 150

 aatcatcaag ggattgacaa aatatatgac tgccaaggtt tactgccacc 200

 tccagagaag ctcactgccg aggtcctagg aatcatttgc attgtcctga 250

 tggccactgt gttaaaaaca atagttctta ttcctttcct ggagcagaac 300

 aattcttccc cgaatacaag aacgcagaaa gcacgtcctt gtggccattg 350

 tcctgaggag tggattacat attccaacag ttgttactac attggtaagg 400

 aaagaagaac ttgggaagag agtttgcagg cctgtgcttc aaagaactct 450

 tctagtctgc tttctataga taatgaagaa gaaatgaaat ttctggccag 500

 cattttacct tcctcatgga ttggtgtgtt tcgtaacagc agtcatcatc 550

 catgggtgac aataaatggt ttggctttca aacatgagat aaaagactca 600

 gatcatgctg aacgtaactg tgcaatgcta catgtacgtg gacttatatc 650

 agaccagtgt ggatcttcaa gaatcattgt gagcataagc tttagaatta 700

 aagcgcttga gcttgcagtg catcagataa aattttatat ttgttcaaac 750

 agaaatgata ttatgattgc ataagcctta aaatgaattg tgttattt 798

<210> 1664
<211> 257
<212> PRT
<213> Homo sapien

<400> 1664
 Met Asn Lys Gln Arg Gly Thr Phe Ser Glu Val Ser Leu Ala Gln
   1               5                  10                  15

 Asp Pro Lys Pro Gln Gln Arg Lys Pro Lys Gly Asn Lys Ser Ser
                  20                  25                  30

 Ile Ser Gly Thr Glu Gln Glu Ile Phe Gln Val Glu Leu Asn Leu
                  35                  40                  45

 Gln Asn Ala Ser Leu Asn His Gln Gly Ile Asp Lys Ile Tyr Asp
                  50                  55                  60

 Cys Gln Gly Leu Leu Pro Pro Pro Glu Lys Leu Thr Ala Glu Val
                  65                  70                  75

 Leu Gly Ile Ile Cys Ile Val Leu Met Ala Thr Val Leu Lys Thr
                  80                  85                  90

 Ile Val Leu Ile Pro Phe Leu Glu Gln Asn Asn Ser Ser Pro Asn
                  95                 100                 105

 Thr Arg Thr Gln Lys Ala Arg Pro Cys Gly His Cys Pro Glu Glu
                 110                 115                 120

 Trp Ile Thr Tyr Ser Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg
                 125                 130                 135

 Arg Thr Trp Glu Glu Ser Leu Gln Ala Cys Ala Ser Lys Asn Ser
                 140                 145                 150

 Ser Ser Leu Leu Ser Ile Asp Asn Glu Glu Glu Met Lys Phe Leu
                 155                 160                 165

 Ala Ser Ile Leu Pro Ser Ser Trp Ile Gly Val Phe Arg Asn Ser
                 170                 175                 180

 Ser His His Pro Trp Val Thr Ile Asn Gly Leu Ala Phe Lys His
                 185                 190                 195

 Glu Ile Lys Asp Ser Asp His Ala Glu Arg Asn Cys Ala Met Leu
                 200                 205                 210

 His Val Arg Gly Leu Ile Ser Asp Gln Cys Gly Ser Ser Arg Ile
                 215                 220                 225

 Ile Val Ser Ile Ser Phe Arg Ile Lys Ala Leu Glu Leu Ala Val
                 230                 235                 240

 His Gln Ile Lys Phe Tyr Ile Cys Ser Asn Arg Asn Asp Ile Met
                 245                 250                 255

 Ile Ala


<210> 1665
<211> 1916
<212> DNA
<213> Homo sapien

<400> 1665
 acttctgaca gtggggaaag cagctgtgtg tgatagcttg gaaggtttac 50

 tgctgcctca agtcctcttc tctgcagttg aggtttcagg tttcaatcct 100

 cccaatacca caagacagag cacggggcgg ctgccgcctc cgcctccgcg 150

 ccttaaccta ggcggcttgc cgaagatctc agccccgcgg ccgcgcgctc 200

 gccctgccct agaccagggt tgggcgcagc ggcggaggtg gcttctgggc 250

 tgcgcgagct gggagagctg ggaggcggcg atcgcagctg ggccgggact 300

 tccttcctcc accgcacggc aacaaaacaa ccctgcggca ggcactgagt 350

 gcttcgcagc tgtctgggcg agaggcacag cgatgggctc cgtgctgagc 400

 accgacagcg gcaaatcggc gcccgcctct gccaccgcgc gggccctgga 450

 gcgcaggagg gacccggagt tgcccgtcac gtccttcgac tgcgccgtgt 500

 gccttgaggt gttacaccag cctgtccgga cccgctgcgg ccacgtattc 550

 tgccgttcct gtattgctac cagtctgaag aacaacaagt ggacctgtcc 600

 ttattgccgg gcatatcttc cttcagaagg agttccagca actgatgtag 650

 ccaaaagaat gaaatcagag tataagaact gcgctgagtg tgacaccctg 700

 gtttgcctca gtgaaatgag ggcacatatt cggacttgtc agaagtacat 750

 agataagtat ggaccactac aagaacttga ggagacagca gcaaggtgtg 800

 tatgtccctt ttgtcagagg gaactgtatg aagacagctt gctggatcat 850

 tgtattactc atcacagatc ggaacggagg cctgtgttct gtccactttg 900

 ccgtttaata cccgatgaga atccaagcag cttcagcggc aatttaataa 950

 gacatctgca agttagtcac actttgtttt atgatgattt catagatttt 1000

 aatataattg aggaagctct tatccgaaga gtcttagacc ggtcacttct 1050

 tgaatatgtg aatcactcga acaccacata attttattaa aacgaaggga 1100

 aaagggacca ctgaattgca ccatttaaga tgctgcttga acaaatggga 1150

 gggaagttgt caatgattga tgggcaaaaa tgtacaacac agttatgtgt 1200

 ttgtccatgt ttattgttat agtgcattta aaaactgctt taattttaat 1250

 ggtttaaatc tgttttacat ccttgagatt cttacacatc taacaacaaa 1300

 aaaaattatc tacatcagtc attgttacat ggaaaagaca ggtggtaggc 1350

 aagtaggtgg aggatctcgg tttgcaaatt agataatact ctgtgtataa 1400

 tgctacatat caataactac catcatggtt aggcacgata actaatcttt 1450

 gttctgtgta aaaaaatatg gagagtgaaa caaagtgcag acattcaaag 1500

 aaataagaaa tctgctccaa tgctcttgtt ctaatctcta ataggttaac 1550

 gttaataatc ttgtatggga gttggaaagg aaaattttgg aagtcaagaa 1600

 agtccattta ggccggacgc ggtggcttac gcttgtagtc ccagcacttt 1650

 gggaggctga ggcaggcgga tcacagggtc gggagttcga gaccagcctg 1700

 gccaacactg gtctctgtga aactccgtct ctactgaaaa tgcaaagatt 1750

 ggctggacgt gttggcgggc atctgtgata ccagctactt gggaggctga 1800

 ggcagaagaa tcgcttgagc ccgggaggcg gaggttgcag tgagctgaga 1850

 tcgcgccagt acactccagc ctgggtaaca gagctagact ccatctcaaa 1900

 aaaaaaaaaa aaaaaa 1916

<210> 1666
<211> 232
<212> PRT
<213> Homo sapien

<400> 1666
 Met Gly Ser Val Leu Ser Thr Asp Ser Gly Lys Ser Ala Pro Ala
   1               5                  10                  15

 Ser Ala Thr Ala Arg Ala Leu Glu Arg Arg Arg Asp Pro Glu Leu
                  20                  25                  30

 Pro Val Thr Ser Phe Asp Cys Ala Val Cys Leu Glu Val Leu His
                  35                  40                  45

 Gln Pro Val Arg Thr Arg Cys Gly His Val Phe Cys Arg Ser Cys
                  50                  55                  60

 Ile Ala Thr Ser Leu Lys Asn Asn Lys Trp Thr Cys Pro Tyr Cys
                  65                  70                  75

 Arg Ala Tyr Leu Pro Ser Glu Gly Val Pro Ala Thr Asp Val Ala
                  80                  85                  90

 Lys Arg Met Lys Ser Glu Tyr Lys Asn Cys Ala Glu Cys Asp Thr
                  95                 100                 105

 Leu Val Cys Leu Ser Glu Met Arg Ala His Ile Arg Thr Cys Gln
                 110                 115                 120

 Lys Tyr Ile Asp Lys Tyr Gly Pro Leu Gln Glu Leu Glu Glu Thr
                 125                 130                 135

 Ala Ala Arg Cys Val Cys Pro Phe Cys Gln Arg Glu Leu Tyr Glu
                 140                 145                 150

 Asp Ser Leu Leu Asp His Cys Ile Thr His His Arg Ser Glu Arg
                 155                 160                 165

 Arg Pro Val Phe Cys Pro Leu Cys Arg Leu Ile Pro Asp Glu Asn
                 170                 175                 180

 Pro Ser Ser Phe Ser Gly Asn Leu Ile Arg His Leu Gln Val Ser
                 185                 190                 195

 His Thr Leu Phe Tyr Asp Asp Phe Ile Asp Phe Asn Ile Ile Glu
                 200                 205                 210

 Glu Ala Leu Ile Arg Arg Val Leu Asp Arg Ser Leu Leu Glu Tyr
                 215                 220                 225

 Val Asn His Ser Asn Thr Thr
                 230

<210> 1667
<211> 1705
<212> DNA
<213> Homo sapien

<400> 1667
 gtttttttcc cttctgagca atggagctta ccatctttat cctgagactg 50

 gccatttaca tcctgacatt tcccttgtac ctgctgaact ttctgggctt 100

 gtggagctgg atatgcaaaa aatggttccc ctacttcttg gtgaggttca 150

 ctgtgatata caacgaacag atggcaagca agaagcggga gctcttcagt 200

 aacctgcagg agtttgcggg cccctccggg aaactctccc tgctggaagt 250

 gggctgtggc acgggggcca acttcaagtt ctacccacct gggtgcaggg 300

 tgacctgtat tgaccccaac cccaactttg agaagttttt gatcaagagc 350

 attgcagaga accgacacct gcagtttgag cgctttgtgg tagctgccgg 400

 ggagaacatg caccaggtgg ctgatggctc tgtggatgtg gtggtctgca 450

 ccctggtgct gtgctctgtg aagaaccagg agcggattct ccgcgaggtg 500

 tgcagagtgc tgagaccggg aggggctttc tatttcatgg agcatgtggc 550

 agctgagtgt tcgacttgga attacttctg gcaacaagtc ctggatcctg 600

 cctggcacct tctgtttgat gggtgcaacc tgaccagaga gagctggaag 650

 gccctggagc gggccagctt ctctaagctg aagctgcagc acatccaggc 700

 cccactgtcc tgggagttgg tgcgccctca tatctatgga tatgctgtga 750

 aatagtgtga gctggcagtt aagagctgaa tggctcaaag aatttaaagc 800

 ttcagtttta catttaaaat gctaagtggg agaagagaaa cctttttttt 850

 ggggggcggt ttttttggtt tgttgttggt tttttttttt tttttggcaa 900

 gactccgtct caaaaaaaaa aaaaaaaaaa aaaagaagta gagacaggga 950

 gacagggtct cactgtgttg cctaggccgg tcttgaactc ctgggctcaa 1000

 gtgattctcc caccttgacc tcctaaattg ttgggattac aggtgtgaga 1050

 cagtgcacct ggccgaaata gctcaagttt ctgaaaaaca aatctgaatc 1100

 tatttgttat tcttagcgtc actggtctgg ctttcagaat taacatacaa 1150

 ggttgccaca cctagttctg cccagcttta tgtcttttat tccagtattc 1200

 caccaaagtt tgttttcctg cattccagtt ctcaagtctt aagataaaga 1250

 ttgtacttga cagtttagta tatccataaa actatttgag gtggttaagg 1300

 ttcttgggtt cattttcctt aatactttgc tgaatattgt agattgtagg 1350

 caatgaaaaa gtctactaaa ttaggaaaac cttgaataat taggtatcct 1400

 aggtaagagc ccctaaacat caagcaatct gtgagtctgt aaagaaataa 1450

 atattttttg gattattctt atctaattcc acccctgttg gaagatgatt 1500

 tctttgttct ttgcaactat ggaagctgtg aaaatcatca caagtgcctc 1550

 tgaaagcgag tgttaggttg gttagagggt ttaatatttt ctgcaatggt 1600

 ttgtaggaat tttaataaat gtagtatatt ttctgagatg attttgtaaa 1650

 agtactattt taaatatcaa atcaaccaat aaattcacat ttgtgttagg 1700

 aacag 1705

<210> 1668
<211> 244
<212> PRT
<213> Homo sapien

<400> 1668
 Met Glu Leu Thr Ile Phe Ile Leu Arg Leu Ala Ile Tyr Ile Leu
   1               5                  10                  15

 Thr Phe Pro Leu Tyr Leu Leu Asn Phe Leu Gly Leu Trp Ser Trp
                  20                  25                  30

 Ile Cys Lys Lys Trp Phe Pro Tyr Phe Leu Val Arg Phe Thr Val
                  35                  40                  45

 Ile Tyr Asn Glu Gln Met Ala Ser Lys Lys Arg Glu Leu Phe Ser
                  50                  55                  60

 Asn Leu Gln Glu Phe Ala Gly Pro Ser Gly Lys Leu Ser Leu Leu
                  65                  70                  75

 Glu Val Gly Cys Gly Thr Gly Ala Asn Phe Lys Phe Tyr Pro Pro
                  80                  85                  90

 Gly Cys Arg Val Thr Cys Ile Asp Pro Asn Pro Asn Phe Glu Lys
                  95                 100                 105

 Phe Leu Ile Lys Ser Ile Ala Glu Asn Arg His Leu Gln Phe Glu
                 110                 115                 120

 Arg Phe Val Val Ala Ala Gly Glu Asn Met His Gln Val Ala Asp
                 125                 130                 135

 Gly Ser Val Asp Val Val Val Cys Thr Leu Val Leu Cys Ser Val
                 140                 145                 150

 Lys Asn Gln Glu Arg Ile Leu Arg Glu Val Cys Arg Val Leu Arg
                 155                 160                 165

 Pro Gly Gly Ala Phe Tyr Phe Met Glu His Val Ala Ala Glu Cys
                 170                 175                 180

 Ser Thr Trp Asn Tyr Phe Trp Gln Gln Val Leu Asp Pro Ala Trp
                 185                 190                 195

 His Leu Leu Phe Asp Gly Cys Asn Leu Thr Arg Glu Ser Trp Lys
                 200                 205                 210

 Ala Leu Glu Arg Ala Ser Phe Ser Lys Leu Lys Leu Gln His Ile
                 215                 220                 225

 Gln Ala Pro Leu Ser Trp Glu Leu Val Arg Pro His Ile Tyr Gly
                 230                 235                 240

 Tyr Ala Val Lys


<210> 1669
<211> 5360
<212> DNA
<213> Homo sapien

<400> 1669
 ttgaggtgca ttgaaatgtt ccaagctgtt acttacctta acatgttctt 50

 gaggtaccat ggcatggatt aaaaggaaat ttggtaagtg gcctccactt 100

 aaacgactta ctagggaagc tatgtgaaat tatttaaaag ggcgagggga 150

 tcaaatagta cttatccttc atgcaaaagt tgtacagaag tcatatggaa 200

 tgaaaaaggt tttttgccct cccccttgtg tatatcttat gggcagtgga 250

 tggaagaaaa taaaattaca aatgaaatgc gatggttgtt ctgaacaagg 300

 ctctcatcca tgtgcattta ttgggatagg aaatagtgac caagaaatgc 350

 agcagctaaa cttggaagga aagaactatt gcacagccaa aacattgtac 400

 atatctgatt cagacaagca aaagcacttc atgttgtctg taaaggtgtt 450

 ctatggcaac ggtgatgaca ttggtgtgtt cctcagcaag tcgtccaaac 500

 cttccaaaaa gaagcagtca ttgaaaaatg ctgacttatg cattggctca 550

 ggaacaaagg tggctctgtt taatcgacta cgatcccaga cagttagtac 600

 cagatacttg catgtagaag gagggaattt tcatgccagt tcacagcagt 650

 ggggagcatt tacattattc ttggatgatg atggatcaga aggagaagaa 700

 ttcacagtca gagatggcta cattcattat ggacaaacag tcaagcttgt 750

 gtgctcagtt actggcatgg cactcccaag attgataatt aggaaagttg 800

 ataagcagac cacattattg gatgcagatg atcctgtgtc acaactccat 850

 aaatgtgcat ttgaccttga ggatacagaa agaatgtact tatgcctttc 900

 tcaagaaaga ataattcaat ttcaggccac tccatgccca acagaaccaa 950

 ataaagagat gataaatgat ggtgcttcct gggcaatcat tagcacacat 1000

 aaggcgaagt atacatttta tgagagaatg ggccctgtcc ttgccctggt 1050

 catgcctatg cctgtcgtag agagccttaa gttgaatggc ggtggggacg 1100

 aagcaatgct tgaacttaca ggacagaatt tcactccaaa tttacgagtg 1150

 tggtttgggg atgtagaagc tgaaactatg tacaggtgtg gagagagtat 1200

 gctccgtgtt gtcccagacg ttctgcattc tgagaaggtt ggagatagtt 1250

 cccagcaacc agtccaggtt tcagtaactt tggtccgaaa tgatggaatc 1300

 atatattcca ccagccttac ctttacctac acaccagaag cagggccgcg 1350

 gccacattgc agtgtagcag gcgcaatcct taaggccagt tcaagccacg 1400

 tgccccctaa tgaattaaac acaaacagcg atggaagtta cacaaatgcc 1450

 agcacaaatt caaccagtgt cacatcatct acaccaacag tggtatcctg 1500

 aactaccgtc tttttgctaa gactcaaacg gcttgagtgc agcaaaaagt 1550

 tgacaaaaaa ggaaaaaaaa atgaacagtc ttttgtggtt tattgggaaa 1600

 cttttcatac caggtgatac tattctaaaa ccccgttgtc tccctgcaag 1650

 tgctgatttg aaatgcagaa gccacagtaa aaaaaaaaaa aaaaaaaaaa 1700

 aaaaaagaaa aaaaaatcaa aatgtataaa tattggaaat caagtttttc 1750

 agctgttttg ttggttggtt ggttggtttt tgtttggttt tgtttaaagg 1800

 gacaagaagt aaataatgtg gctggaatac aagttgaaca aactagaaga 1850

 cacaaatcta acatagtttt tatggaccaa ggaacttgta tattgtataa 1900

 gctttagtaa aaggtacatt ttcaccatac ctttttttat atcacggtat 1950

 tatagtacac cttgttacca ataggttgtt ctcttcccca ccctcctttg 2000

 agctttgctc taaaatacat tctggttcca agcctgacca tccttgttta 2050

 atctatcata ctcttccagg tttttttttt tggtctaagg ctggaacttt 2100

 tttctttttt tttcagctga agtcttatga ctttttcatg agtcaaaatt 2150

 gtttggattt cacgaagtca aatcttgcaa aggcctgcat atttttttta 2200

 agattatatg aagtctgtgc aaaaagcttt aaaaaattgc ctctgccttg 2250

 cctgcataca tgcaatgtat gtaacttagt ctctcttctc agacactgtt 2300

 gggtagttat ttctgtgttt tcttttttta aaaaaaaata tggacttatt 2350

 gtggtttatc tgagaggttc taacattcac atgcaatttg gtgtggcatt 2400

 tagctattat gagttattgg cgcgaacttg tttgatattt gaagtgtctc 2450

 tccccttttc ccatgacgta atacataggt gtgttccagg atttgttcag 2500

 gtttttcccc ccctcctaat cttgtacata acttgtattt tgtgtaagtt 2550

 aaacatttta tttgaacttg gaatgttccc agtgatttca ttcagcaggg 2600

 tattttctgc cttgttggca agtagcaaaa aatatgggaa gtatttgcta 2650

 ccagttgtta gatggtgccc cttattggta gaatcaggaa aatgtccgca 2700

 aaagcatgtt ttattatctt tacttttttg gggggttgga gggggtagcc 2750

 tagccagaca tcatgtaatc ttaaaacata agatgctttt attagatgat 2800

 caactaaaaa tagctggaag acagtacttt agaaacaaaa tagttagtaa 2850

 gatatataat gcaaatgtaa cttatgtttt catttttttc tctgcctttt 2900

 ttttttgttt tttttctttt tttccagtac tgagcatctc cacaaatgtc 2950

 tcctactcag aaaatgtttc ttttctttca gttgagattt ggtgcattca 3000

 gggttgtagg ttggccttgc ttgctaaccc gccggtttta ccgtgcttta 3050

 ttcctgaact ttgtttatgc ctttgtttgg ttcttctgaa attgcagcag 3100

 actcattggg ctacatttag tacaggaacc acgtgtgtaa tgttatacaa 3150

 cacagtcagt aatacaatca tccctcttag agtaaaaact acctctagat 3200

 tgtgtaagct ttttactgtc cataaaacag gagccacagt accttatgaa 3250

 tgcaaaactg taacttccta cagtgtttcc ccacagaaca ttgtctttct 3300

 ggtgtctggg ctgtttttga aaaagtttcc attaatagac tttttagaaa 3350

 ttattattag tagcattttt tttccagctt tgcgtcttca tcactcactc 3400

 aagtgtcaga ctatgcactg taaatatctt cctaacatct ttaaatcgcc 3450

 ttttcctcag ttttcaaggg gaaggtcatt tgtaaagcac gttaggtggt 3500

 taaatcagtt attgcggttt tctcttacag caagcctttt taatcacccc 3550

 caggctgcat tttattctat atcgcctttt ttcttcaaat ctgctccaat 3600

 catccacttc tctcttataa gctattcctg cctcacacct aaatctgttt 3650

 cagtgatcaa gggcagaact cattgtggcc ttatctttct ttgttgtaat 3700

 tgttcactgt ctctttctta cagaccactt attctgagta gtagttattc 3750

 ctccctatgg agtcatggca ggaatcatta cacagtgctt ttgttcagag 3800

 catggacatg ttccaggtgc tgctttgctt taacggccac aagtttcctc 3850

 cacttctcag gtttggtatt tagtaaggaa tcaattaaat taaccaataa 3900

 caaaagagat acttttgaag aacaaactat tctttaccca ttttgtagct 3950

 caaaaataat ttttcaagtt catgacctta ttaaaatgaa cttgtgtttt 4000

 tttaacaaac gtctatttta ttttgatagt ttctttccga agataattga 4050

 aatattatac tgtaaccctt ttcttttctt ttttgaaaag tccaagaatg 4100

 tacttataca ggatttttcc ccacctattt ttggccattc tcataccaca 4150

 gacaaaagag tgaatgattg tcattgtagc ttattgttta tcagtagttc 4200

 ttttgtagct gcttacattt tttctttcat ggtttgtgaa tcatttcagt 4250

 atgtaattta taggaacctt gtcctctggt atagtagact gtgtgccctc 4300

 ctccaggatg gcattattag acatgctggt catttaccct cagaaagact 4350

 ctcttataga atggtgagtg cttcagttat agtatgtttg aattttaaaa 4400

 aattcctgtt tagaatgtat ctatgctctc atgactatgc agtttctaac 4450

 atacacatag aagctgagtc tctgatccaa tatgttttta tttgttccat 4500

 taatttatca catagattgg gaaggcaagc taaaagcctt aaaaatgccc 4550

 tttatatttt gagtgatttc agcgttgaac acagtatact atctaaattt 4600

 gctgctcact ttcttaaact gttgcaatta aaggcatgtt tatacatgac 4650

 taatcgtgaa atgtttgtca ctcttactgc acagacttat ctgcaatcaa 4700

 actggttagt ttttttgttt tgttttgttt tattgttttt aatgaatctg 4750

 gtaccatctg tgctttcaca aaaaacttcc aatgccattt ttgagaacta 4800

 acctaacagt catgctaacc agaaaatcca ctggggagga ggttcctttg 4850

 aaacaaaatg ctgttcagtt agtaaccaag ttactttgat tgcaaaagca 4900

 gctgtgtttc tgataagtac tgaacaaatg tgtgtaattt tctgtgccag 4950

 acttatgact ttgttttcaa gcactgtaat gtgggatgga tggttagaaa 5000

 caataatata tagggtttct gttaaccctt tcaggactca actgtatctc 5050

 cttttgttaa ttttcccctg tgttgtgata aattgtttgc cagcattcag 5100

 tactgtgttg gtgcagatga ggtttatatc tcattttagc ttatttcttg 5150

 tacctttcag catgcctacg cattcagtcc ttaaggggtt tattttacaa 5200

 actgtgcgcc tgaagtttat tagcaataag atagaaaatg agcaagttta 5250

 taccataatt ttgagaaaaa aagaatctgc tcagttccat atttcatccg 5300

 tgaaaaactt gcaatacgag cagtttcaag gaataaataa aaaggaaatg 5350

 aaaccattgt 5360

<210> 1670
<211> 420
<212> PRT
<213> Homo sapien

<400> 1670
 Met Gly Ser Gly Trp Lys Lys Ile Lys Leu Gln Met Lys Cys Asp
   1               5                  10                  15

 Gly Cys Ser Glu Gln Gly Ser His Pro Cys Ala Phe Ile Gly Ile
                  20                  25                  30

 Gly Asn Ser Asp Gln Glu Met Gln Gln Leu Asn Leu Glu Gly Lys
                  35                  40                  45

 Asn Tyr Cys Thr Ala Lys Thr Leu Tyr Ile Ser Asp Ser Asp Lys
                  50                  55                  60

 Gln Lys His Phe Met Leu Ser Val Lys Val Phe Tyr Gly Asn Gly
                  65                  70                  75

 Asp Asp Ile Gly Val Phe Leu Ser Lys Ser Ser Lys Pro Ser Lys
                  80                  85                  90

 Lys Lys Gln Ser Leu Lys Asn Ala Asp Leu Cys Ile Gly Ser Gly
                  95                 100                 105

 Thr Lys Val Ala Leu Phe Asn Arg Leu Arg Ser Gln Thr Val Ser
                 110                 115                 120

 Thr Arg Tyr Leu His Val Glu Gly Gly Asn Phe His Ala Ser Ser
                 125                 130                 135

 Gln Gln Trp Gly Ala Phe Thr Leu Phe Leu Asp Asp Asp Gly Ser
                 140                 145                 150

 Glu Gly Glu Glu Phe Thr Val Arg Asp Gly Tyr Ile His Tyr Gly
                 155                 160                 165

 Gln Thr Val Lys Leu Val Cys Ser Val Thr Gly Met Ala Leu Pro
                 170                 175                 180

 Arg Leu Ile Ile Arg Lys Val Asp Lys Gln Thr Thr Leu Leu Asp
                 185                 190                 195

 Ala Asp Asp Pro Val Ser Gln Leu His Lys Cys Ala Phe Asp Leu
                 200                 205                 210

 Glu Asp Thr Glu Arg Met Tyr Leu Cys Leu Ser Gln Glu Arg Ile
                 215                 220                 225

 Ile Gln Phe Gln Ala Thr Pro Cys Pro Thr Glu Pro Asn Lys Glu
                 230                 235                 240

 Met Ile Asn Asp Gly Ala Ser Trp Ala Ile Ile Ser Thr His Lys
                 245                 250                 255

 Ala Lys Tyr Thr Phe Tyr Glu Arg Met Gly Pro Val Leu Ala Leu
                 260                 265                 270

 Val Met Pro Met Pro Val Val Glu Ser Leu Lys Leu Asn Gly Gly
                 275                 280                 285

 Gly Asp Glu Ala Met Leu Glu Leu Thr Gly Gln Asn Phe Thr Pro
                 290                 295                 300

 Asn Leu Arg Val Trp Phe Gly Asp Val Glu Ala Glu Thr Met Tyr
                 305                 310                 315

 Arg Cys Gly Glu Ser Met Leu Arg Val Val Pro Asp Val Leu His
                 320                 325                 330

 Ser Glu Lys Val Gly Asp Ser Ser Gln Gln Pro Val Gln Val Ser
                 335                 340                 345

 Val Thr Leu Val Arg Asn Asp Gly Ile Ile Tyr Ser Thr Ser Leu
                 350                 355                 360

 Thr Phe Thr Tyr Thr Pro Glu Ala Gly Pro Arg Pro His Cys Ser
                 365                 370                 375

 Val Ala Gly Ala Ile Leu Lys Ala Ser Ser Ser His Val Pro Pro
                 380                 385                 390

 Asn Glu Leu Asn Thr Asn Ser Asp Gly Ser Tyr Thr Asn Ala Ser
                 395                 400                 405

 Thr Asn Ser Thr Ser Val Thr Ser Ser Thr Pro Thr Val Val Ser
                 410                 415                 420

<210> 1671
<211> 2867
<212> DNA
<213> Homo sapien

<400> 1671
 tcccgtggag cagaggggca aagtggcagg aacctcttaa agggcgagac 50

 gggcggcgac cgagaacgcg gtcggcccgg tccccgccgc acccagccca 100

 gagaagagtt tagtgactga ggccgaaaat tcacagcacc aacagaagga 150

 agagggtgag gaagccataa actcaggcca acaagaacct cagcaggagg 200

 aatcttgtca aacagcagct gaaggagata attggtgtga acacaaggtg 250

 aaagcttcta atggagacac tcctacacat gaagacttga ccaagaacaa 300

 ggagcggaca tcagaaagca gaggactttc acgactattc tcctcgtttc 350

 tcaaaaggcc caaatctcag gtgtccgagg aagaaggcaa agaagtagag 400

 tcagataaag aaaaaggtga aggaggtcag aaagagatag aatttggaac 450

 cagtcttgat gaagagatca ttttaaaggc cccaattgca gctcctgaac 500

 cggaactcaa aacagaccca tctttggatc ttcattcatt aagcagtgca 550

 gaaacacagc ctcaccatta caattaagaa ttatttttag agtcttctta 600

 tttctgaagc atgtgaatat tatctcgatc gttaaaagtc ctgctcagga 650

 agaactcaga gaagatccag attctgaaat taaggaagga gaaggacttg 700

 aagagtgctc caaaatagaa gtaaaagaag aaagccctca atcaaaagca 750

 gaaacagaat taaaagcttc ccaaaaacca atcagaaaac acaggaacat 800

 gcactgcaag gtttctttgt tggatgacac agtttatgaa tgtgttgtgg 850

 agaaacatgc taagggacaa gatttgctta aacgagtatg tgagcatctc 900

 aatcttttgg aagaagacta ttttggtcta gccatttggg ataacgcaac 950

 ctctaagaca tggctggatt ccgccaaaga aataaaaaag caggttcgtg 1000

 gtgtcccttg gaattttaca tttaatgtaa agttttatcc acctgaccca 1050

 gcacagttaa cagaagacat aacaagatat tatttatgtc ttcagcttcg 1100

 gcaggacata gttgcaggac gtctgccctg ttcctttgca accttagcat 1150

 tattaggttc ttacaccatc cagtctgaac tgggagacta cgacccagaa 1200

 ctccatggcg tggattatgt tagtgatttt aaactggccc cgaatcagac 1250

 caaggaactt gaagagaagg tcatggaact gcataagtca tacaggtcca 1300

 tgactccagc tcaggctgac ttggagtttc ttgagaatgc caaaaagttg 1350

 tctatgtatg gagttgatct tcataaagca aaggacttgg aaggagtaga 1400

 tatcatccta ggtgtctgct ctagtggcct tctggtttac aaagataagc 1450

 tgagaattaa ccgcttccct tggcccaaag tgctgaagat ttcttataaa 1500

 cgtagtagct ttttcatcaa gattcggcct ggagagcaag agcagtatga 1550

 aagtaccatc ggattcaaac ttcccagtta ccgagcagct aagaaattat 1600

 ggaaagtctg tgtagaacat cacacgtttt tcagattgac atctacagac 1650

 accattccca aaagcaaatt tcttgcgcta ggatccaaat ttcgatacag 1700

 tggccggact caagctcaga ccaggcaagc tagtgctcta attgacaggc 1750

 ctgccccaca cttcgagcgt acagcaagta aacgggcgtc ccggagcctc 1800

 gatggagcag cagctgtcga ttcggcagac cgaagtcctc ggcccacttc 1850

 tgcacctgcc attactcagg gtcaggttgc agaaggtggc gtcctagatg 1900

 cctctgctaa aaaaacagtg gtccctaaag cacagaagga aacagtgaag 1950

 gctgaagtga aaaaggaaga cgagccacct gagcaagctg agccagagcc 2000

 cacagaagca tggaagaaaa agagagaaag actagatggt gaaaacattt 2050

 atatcagaca tagcaattta atgttggagg atttagacaa gagtcaagag 2100

 gagatcaaaa aacatcatgc cagcatcagt gagctgaaaa agaacttcat 2150

 ggagtctgta ccagaaccac ggcctagtga atgggataaa cgcttatcca 2200

 ctcactcacc cttccgaact cttaacatca atgggcaaat ccccacagga 2250

 gaaggacctc ccctggtgaa gacacaaact gtcaccatct cagataatgc 2300

 caatgctgtg aaaagtgaaa tcccaaccaa agacgtccct attgtccaca 2350

 ctgagaccaa gaccatcact tatgaggctg cccagactgt aaaaggtggg 2400

 atttcagaga cacgtattga aaagagaatt gtgatcacag gagatgctga 2450

 tattgaccat gatcaggtcc ttgtacaagc catcaaggag gcaaaggagc 2500

 agcacccaga catgtcagtg accaaggtgg tcgtccacca ggagaccgag 2550

 attgctgatg agtgagctca ggaactaacc taccccaact ctgcccttct 2600

 cccatccaag agaaaccacg aaaatgataa agaagctaac ctgccatagt 2650

 cagacttcag actttcaaga ttattctaaa tcaccagaaa attaatttca 2700

 gtttctattg ggagtttata ccaagagatt cttctagatc tcattgatcc 2750

 ttttgaagag ctttttctat attaggatat cagaattgtt caacttttca 2800

 ctctatagac tgttttaaga gttttggggg gtttttaatt gggtggtttg 2850

 taaccccttc agcctag 2867

<210> 1672
<211> 588
<212> PRT
<213> Homo sapien

<400> 1672
 Met His Cys Lys Val Ser Leu Leu Asp Asp Thr Val Tyr Glu Cys
   1               5                  10                  15

 Val Val Glu Lys His Ala Lys Gly Gln Asp Leu Leu Lys Arg Val
                  20                  25                  30

 Cys Glu His Leu Asn Leu Leu Glu Glu Asp Tyr Phe Gly Leu Ala
                  35                  40                  45

 Ile Trp Asp Asn Ala Thr Ser Lys Thr Trp Leu Asp Ser Ala Lys
                  50                  55                  60

 Glu Ile Lys Lys Gln Val Arg Gly Val Pro Trp Asn Phe Thr Phe
                  65                  70                  75

 Asn Val Lys Phe Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp
                  80                  85                  90

 Ile Thr Arg Tyr Tyr Leu Cys Leu Gln Leu Arg Gln Asp Ile Val
                  95                 100                 105

 Ala Gly Arg Leu Pro Cys Ser Phe Ala Thr Leu Ala Leu Leu Gly
                 110                 115                 120

 Ser Tyr Thr Ile Gln Ser Glu Leu Gly Asp Tyr Asp Pro Glu Leu
                 125                 130                 135

 His Gly Val Asp Tyr Val Ser Asp Phe Lys Leu Ala Pro Asn Gln
                 140                 145                 150

 Thr Lys Glu Leu Glu Glu Lys Val Met Glu Leu His Lys Ser Tyr
                 155                 160                 165

 Arg Ser Met Thr Pro Ala Gln Ala Asp Leu Glu Phe Leu Glu Asn
                 170                 175                 180

 Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His Lys Ala Lys
                 185                 190                 195

 Asp Leu Glu Gly Val Asp Ile Ile Leu Gly Val Cys Ser Ser Gly
                 200                 205                 210

 Leu Leu Val Tyr Lys Asp Lys Leu Arg Ile Asn Arg Phe Pro Trp
                 215                 220                 225

 Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Ser Ser Phe Phe Ile
                 230                 235                 240

 Lys Ile Arg Pro Gly Glu Gln Glu Gln Tyr Glu Ser Thr Ile Gly
                 245                 250                 255

 Phe Lys Leu Pro Ser Tyr Arg Ala Ala Lys Lys Leu Trp Lys Val
                 260                 265                 270

 Cys Val Glu His His Thr Phe Phe Arg Leu Thr Ser Thr Asp Thr
                 275                 280                 285

 Ile Pro Lys Ser Lys Phe Leu Ala Leu Gly Ser Lys Phe Arg Tyr
                 290                 295                 300

 Ser Gly Arg Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile
                 305                 310                 315

 Asp Arg Pro Ala Pro His Phe Glu Arg Thr Ala Ser Lys Arg Ala
                 320                 325                 330

 Ser Arg Ser Leu Asp Gly Ala Ala Ala Val Asp Ser Ala Asp Arg
                 335                 340                 345

 Ser Pro Arg Pro Thr Ser Ala Pro Ala Ile Thr Gln Gly Gln Val
                 350                 355                 360

 Ala Glu Gly Gly Val Leu Asp Ala Ser Ala Lys Lys Thr Val Val
                 365                 370                 375

 Pro Lys Ala Gln Lys Glu Thr Val Lys Ala Glu Val Lys Lys Glu
                 380                 385                 390

 Asp Glu Pro Pro Glu Gln Ala Glu Pro Glu Pro Thr Glu Ala Trp
                 395                 400                 405

 Lys Lys Lys Arg Glu Arg Leu Asp Gly Glu Asn Ile Tyr Ile Arg
                 410                 415                 420

 His Ser Asn Leu Met Leu Glu Asp Leu Asp Lys Ser Gln Glu Glu
                 425                 430                 435

 Ile Lys Lys His His Ala Ser Ile Ser Glu Leu Lys Lys Asn Phe
                 440                 445                 450

 Met Glu Ser Val Pro Glu Pro Arg Pro Ser Glu Trp Asp Lys Arg
                 455                 460                 465

 Leu Ser Thr His Ser Pro Phe Arg Thr Leu Asn Ile Asn Gly Gln
                 470                 475                 480

 Ile Pro Thr Gly Glu Gly Pro Pro Leu Val Lys Thr Gln Thr Val
                 485                 490                 495

 Thr Ile Ser Asp Asn Ala Asn Ala Val Lys Ser Glu Ile Pro Thr
                 500                 505                 510

 Lys Asp Val Pro Ile Val His Thr Glu Thr Lys Thr Ile Thr Tyr
                 515                 520                 525

 Glu Ala Ala Gln Thr Val Lys Gly Gly Ile Ser Glu Thr Arg Ile
                 530                 535                 540

 Glu Lys Arg Ile Val Ile Thr Gly Asp Ala Asp Ile Asp His Asp
                 545                 550                 555

 Gln Val Leu Val Gln Ala Ile Lys Glu Ala Lys Glu Gln His Pro
                 560                 565                 570

 Asp Met Ser Val Thr Lys Val Val Val His Gln Glu Thr Glu Ile
                 575                 580                 585

 Ala Asp Glu


<210> 1673
<211> 1979
<212> DNA
<213> Homo sapien

<400> 1673
 caggactgcc tgagacaagc cacaagctga acagagaaag tggattgaac 50

 aaggacgcat ttccccagta catccacaac atgctgtcca catctcgttc 100

 tcggtttatc agaaatacca acgagagcgg tgaagaagtc accacctttt 150

 ttgattatga ttacggtgct ccctgtcata aatttgacgt gaagcaaatt 200

 ggggcccaac tcctgcctcc gctctactcg ctggtgttca tctttggttt 250

 tgtgggcaac atgctggtcg tcctcatctt aataaactgc aaaaagctga 300

 agtgcttgac tgacatttac ctgctcaacc tggccatctc tgatctgctt 350

 tttcttatta ctctcccatt gtgggctcac tctgctgcaa atgagtgggt 400

 ctttgggaat gcaatgtgca aattattcac agggctgtat cacatcggtt 450

 attttggcgg aatcttcttc atcatcctcc tgacaatcga tagatacctg 500

 gctattgtcc atgctgtgtt tgctttaaaa gccaggacgg tcacctttgg 550

 ggtggtgaca agtgtgatca cctggttggt ggctgtgttt gcttctgtcc 600

 caggaatcat ctttactaaa tgccagaaag aagattctgt ttatgtctgt 650

 ggcccttatt ttccacgagg atggaataat ttccacacaa taatgaggaa 700

 cattttgggg ctggtcctgc cgctgctcat catggtcatc tgctactcgg 750

 gaatcctgaa aaccctgctt cggtgtcgaa acgagaagaa gaggcatagg 800

 gcagtgagag tcatcttcac catcatgatt gtttactttc tcttctggac 850

 tccctataac attgtcattc tcctgaacac cttccaggaa ttcttcggcc 900

 tgagtaactg tgaaagcacc agtcaactgg accaagccac gcaggtgaca 950

 gagactcttg ggatgactca ctgctgcatc aatcccatca tctatgcctt 1000

 cgttggggag aagttcagaa ggtatctctc ggtgttcttc cgaaagcaca 1050

 tcaccaagcg cttctgcaaa caatgtccag ttttctacag ggagacagtg 1100

 gatggagtga cttcaacaaa cacgccttcc actggggagc aggaagtctc 1150

 ggctggttta taaaacgagg agcagtttga ttgttgttta taaagggaga 1200

 taacaatctg tatataacaa caaacttcaa gggtttgttg aacaatagaa 1250

 acctgtaaag caggtgccca ggaacctcag ggctgtgtgt actaatacag 1300

 actatgtcac ccaatgcata tccaacatgt gctcagggaa taatccagaa 1350

 aaactgtggg tagagacttt gactctccag aaagctcatc tcagctcctg 1400

 aaaaatgcct cattaccttg tgctaatcct ctttttctag tcttcataat 1450

 ttcttcactc aatctctgat tctgtcaatg tcttgaaatc aagggccagc 1500

 tggaggtgaa gaagagaatg tgacaggcac agatgaatgg gagtgaggga 1550

 tagtggggtc agggctgaga ggagaaggag ggagacatga gcatggctga 1600

 gcctggacaa agacaaaggt gagcaaaggg ctcacgcatt cagccaggag 1650

 atgatactgg tccttagccc catctgccac gtgtatttaa ccttgaaggg 1700

 ttcaccaggt cagggagagt ttgggaactg caataacctg ggagttttgg 1750

 tggagtccga tgattctctt ttgcataagt gcatgacata tttttgcttt 1800

 attacagttt atctatggca cccatgcacc ttacatttga aatctatgaa 1850

 atatcatgct ccattgttca gatgcttctt aggccacatc cccctgtcta 1900

 aaaattcaga aaatttttgt ttataaaaga tgcattatct atgatatgct 1950

 aatatatgta tatgcaatat aaaatttag 1979

<210> 1674
<211> 360
<212> PRT
<213> Homo sapien

<400> 1674
 Met Leu Ser Thr Ser Arg Ser Arg Phe Ile Arg Asn Thr Asn Glu
   1               5                  10                  15

 Ser Gly Glu Glu Val Thr Thr Phe Phe Asp Tyr Asp Tyr Gly Ala
                  20                  25                  30

 Pro Cys His Lys Phe Asp Val Lys Gln Ile Gly Ala Gln Leu Leu
                  35                  40                  45

 Pro Pro Leu Tyr Ser Leu Val Phe Ile Phe Gly Phe Val Gly Asn
                  50                  55                  60

 Met Leu Val Val Leu Ile Leu Ile Asn Cys Lys Lys Leu Lys Cys
                  65                  70                  75

 Leu Thr Asp Ile Tyr Leu Leu Asn Leu Ala Ile Ser Asp Leu Leu
                  80                  85                  90

 Phe Leu Ile Thr Leu Pro Leu Trp Ala His Ser Ala Ala Asn Glu
                  95                 100                 105

 Trp Val Phe Gly Asn Ala Met Cys Lys Leu Phe Thr Gly Leu Tyr
                 110                 115                 120

 His Ile Gly Tyr Phe Gly Gly Ile Phe Phe Ile Ile Leu Leu Thr
                 125                 130                 135

 Ile Asp Arg Tyr Leu Ala Ile Val His Ala Val Phe Ala Leu Lys
                 140                 145                 150

 Ala Arg Thr Val Thr Phe Gly Val Val Thr Ser Val Ile Thr Trp
                 155                 160                 165

 Leu Val Ala Val Phe Ala Ser Val Pro Gly Ile Ile Phe Thr Lys
                 170                 175                 180

 Cys Gln Lys Glu Asp Ser Val Tyr Val Cys Gly Pro Tyr Phe Pro
                 185                 190                 195

 Arg Gly Trp Asn Asn Phe His Thr Ile Met Arg Asn Ile Leu Gly
                 200                 205                 210

 Leu Val Leu Pro Leu Leu Ile Met Val Ile Cys Tyr Ser Gly Ile
                 215                 220                 225

 Leu Lys Thr Leu Leu Arg Cys Arg Asn Glu Lys Lys Arg His Arg
                 230                 235                 240

 Ala Val Arg Val Ile Phe Thr Ile Met Ile Val Tyr Phe Leu Phe
                 245                 250                 255

 Trp Thr Pro Tyr Asn Ile Val Ile Leu Leu Asn Thr Phe Gln Glu
                 260                 265                 270

 Phe Phe Gly Leu Ser Asn Cys Glu Ser Thr Ser Gln Leu Asp Gln
                 275                 280                 285

 Ala Thr Gln Val Thr Glu Thr Leu Gly Met Thr His Cys Cys Ile
                 290                 295                 300

 Asn Pro Ile Ile Tyr Ala Phe Val Gly Glu Lys Phe Arg Arg Tyr
                 305                 310                 315

 Leu Ser Val Phe Phe Arg Lys His Ile Thr Lys Arg Phe Cys Lys
                 320                 325                 330

 Gln Cys Pro Val Phe Tyr Arg Glu Thr Val Asp Gly Val Thr Ser
                 335                 340                 345

 Thr Asn Thr Pro Ser Thr Gly Glu Gln Glu Val Ser Ala Gly Leu
                 350                 355                 360

<210> 1675
<211> 1364
<212> DNA
<213> Homo sapien

<400> 1675
 ctgtattgtg gttcctggaa cactttagag gcttgtgatt ctactgcttc 50

 ttattcacac tataatacat gtctcaccaa tagatgattc aagaacatca 100

 tttaaataca caatttttca ttctctattt ttgctaaatt tcttcatact 150

 caactttcag attctttaat ctccagctca gcttcaacaa ttcaacgctg 200

 ttctttctga aaaagtacac atcgtgcctt ctctacttcg ctcttggaac 250

 ataatttctc atggcagtgt ttaagaccac tctgtggagg ttaatttctg 300

 ggaccttagg gataatatgc ctttcgttga tggctacgtt gggaattttg 350

 ttgaaaaatt cttttactaa actgagtatt gagccagcat ttactccagg 400

 acccaacata gaactccaga aagactctga ctgctgttct tgccaagaaa 450

 aatgggttgg gtaccggtgc aactgttact tcatttccag tgaacagaaa 500

 acttggaacg aaagtcggca tctctgtgct tctcagaaat ccagcctgct 550

 tcagcttcaa aacacagatg aactggattt tatgagctcc agtcaacaat 600

 tttactggat tggactctct tacagtgagg agcacaccgc ctggttgtgg 650

 gagaatggct ctgcactctc ccagtatcta tttccatcat ttgaaacttt 700

 taatacaaag aactgcatag cgtataatcc aaatggaaat gctttagatg 750

 aatcctgtga agataaaaat cgttatatct gtaagcaaca gctcatttaa 800

 atgtttcttg gggcagagaa ggtggagagt aaagacccaa cattactaac 850

 aatgatacag ttgcatgtta tattattact aattgtctac ttctggagtc 900

 tataaaatgt ttttaaacag tgtcatatac aattgtcatg tatgtgaaac 950

 aatgtgtttt aaaattgatg aaattcgttc acctacattt gagaattata 1000

 aaattaacat aaagaatttt gtattttcat ttaatgtata taatgttaaa 1050

 ttcaatgtag ttttattaca catttatgta attttattta cattcttgct 1100

 aattctcagc agaaatttaa ataagattta attcacatca aataaaattt 1150

 agaaaataaa atttaactca cactgcccag gctggagcat agtggcaaga 1200

 tcatagctca ttgcaagctc aagtgatcct cctgactcag cctcccaagt 1250

 agctaggact gcaggcacca tgtcactatg cccgactaat ttttaatttt 1300

 taattttttg tcaagacaag gtcttgctat gttgcccagg ctggtcttga 1350

 actcctggcc tcaa 1364

<210> 1676
<211> 179
<212> PRT
<213> Homo sapien

<400> 1676
 Met Ala Val Phe Lys Thr Thr Leu Trp Arg Leu Ile Ser Gly Thr
   1               5                  10                  15

 Leu Gly Ile Ile Cys Leu Ser Leu Met Ala Thr Leu Gly Ile Leu
                  20                  25                  30

 Leu Lys Asn Ser Phe Thr Lys Leu Ser Ile Glu Pro Ala Phe Thr
                  35                  40                  45

 Pro Gly Pro Asn Ile Glu Leu Gln Lys Asp Ser Asp Cys Cys Ser
                  50                  55                  60

 Cys Gln Glu Lys Trp Val Gly Tyr Arg Cys Asn Cys Tyr Phe Ile
                  65                  70                  75

 Ser Ser Glu Gln Lys Thr Trp Asn Glu Ser Arg His Leu Cys Ala
                  80                  85                  90

 Ser Gln Lys Ser Ser Leu Leu Gln Leu Gln Asn Thr Asp Glu Leu
                  95                 100                 105

 Asp Phe Met Ser Ser Ser Gln Gln Phe Tyr Trp Ile Gly Leu Ser
                 110                 115                 120

 Tyr Ser Glu Glu His Thr Ala Trp Leu Trp Glu Asn Gly Ser Ala
                 125                 130                 135

 Leu Ser Gln Tyr Leu Phe Pro Ser Phe Glu Thr Phe Asn Thr Lys
                 140                 145                 150

 Asn Cys Ile Ala Tyr Asn Pro Asn Gly Asn Ala Leu Asp Glu Ser
                 155                 160                 165

 Cys Glu Asp Lys Asn Arg Tyr Ile Cys Lys Gln Gln Leu Ile
                 170                 175

<210> 1677
<211> 1271
<212> DNA
<213> Homo sapien

<400> 1677
 ctgtattgtg gttcctggaa cactttagag gcttgtgatt ctactgcttc 50

 ttattcacac tataatacat gtctcaccaa tagatgattc aagaacatca 100

 tttaaataca caatttttca ttctctattt ttgctaaatt tcttcatact 150

 caactttcag attctttaat ctccagctca gcttcaacaa ttcaacgctg 200

 ttctttctga aaaagtacac atcgtgcctt ctctacttcg ctcttggaac 250

 ataatttctc atggcagctt ttactaaact gagtattgag ccagcattta 300

 ctccaggacc caacatagaa ctccagaaag actctgactg ctgttcttgc 350

 caagaaaaat gggttgggta ccggtgcaac tgttacttca tttccagtga 400

 acagaaaact tggaacgaaa gtcggcatct ctgtgcttct cagaaatcca 450

 gcctgcttca gcttcaaaac acagatgaac tggattttat gagctccagt 500

 caacaatttt actggattgg actctcttac agtgaggagc acaccgcctg 550

 gttgtgggag aatggctctg cactctccca gtatctattt ccatcatttg 600

 aaacttttaa tacaaagaac tgcatagcgt ataatccaaa tggaaatgct 650

 ttagatgaat cctgtgaaga taaaaatcgt tatatctgta agcaacagct 700

 catttaaatg tttcttgggg cagagaaggt ggagagtaaa gacccaacat 750

 tactaacaat gatacagttg catgttatat tattactaat tgtctacttc 800

 tggagtctat aaaatgtttt taaacagtgt catatacaat tgtcatgtat 850

 gtgaaacaat gtgttttaaa attgatgaaa ttcgttcacc tacatttgag 900

 aattataaaa ttaacataaa gaattttgta ttttcattta atgtatataa 950

 tgttaaattc aatgtagttt tattacacat ttatgtaatt ttatttacat 1000

 tcttgctaat tctcagcaga aatttaaata agatttaatt cacatcaaat 1050

 aaaatttaga aaataaaatt taactcacac tgcccaggct ggagcatagt 1100

 ggcaagatca tagctcattg caagctcaag tgatcctcct gactcagcct 1150

 cccaagtagc taggactgca ggcaccatgt cactatgccc gactaatttt 1200

 taatttttaa ttttttgtca agacaaggtc ttgctatgtt gcccaggctg 1250

 gtcttgaact cctggcctca a 1271

<210> 1678
<211> 148
<212> PRT
<213> Homo sapien

<400> 1678
 Met Ala Ala Phe Thr Lys Leu Ser Ile Glu Pro Ala Phe Thr Pro
   1               5                  10                  15

 Gly Pro Asn Ile Glu Leu Gln Lys Asp Ser Asp Cys Cys Ser Cys
                  20                  25                  30

 Gln Glu Lys Trp Val Gly Tyr Arg Cys Asn Cys Tyr Phe Ile Ser
                  35                  40                  45

 Ser Glu Gln Lys Thr Trp Asn Glu Ser Arg His Leu Cys Ala Ser
                  50                  55                  60

 Gln Lys Ser Ser Leu Leu Gln Leu Gln Asn Thr Asp Glu Leu Asp
                  65                  70                  75

 Phe Met Ser Ser Ser Gln Gln Phe Tyr Trp Ile Gly Leu Ser Tyr
                  80                  85                  90

 Ser Glu Glu His Thr Ala Trp Leu Trp Glu Asn Gly Ser Ala Leu
                  95                 100                 105

 Ser Gln Tyr Leu Phe Pro Ser Phe Glu Thr Phe Asn Thr Lys Asn
                 110                 115                 120

 Cys Ile Ala Tyr Asn Pro Asn Gly Asn Ala Leu Asp Glu Ser Cys
                 125                 130                 135

 Glu Asp Lys Asn Arg Tyr Ile Cys Lys Gln Gln Leu Ile
                 140                 145

<210> 1679
<211> 982
<212> DNA
<213> Homo sapien

<400> 1679
 agacaatttt cagcaggaag aagtagaaag gataaaatgg atcctgcacc 50

 acgggaacct cacagcacct cacttctttt ggttttcttt ctctttgggg 100

 cacctctgga ctcactcccc agcatgaagg cgctgagccc ggtgcgcggc 150

 tgctacgagg cggtgtgctg cctgtcggaa cgcagtctgg ccatcgcccg 200

 gggccgaggg aagggcccgg cagctgagga gccgctgagc ttgctggacg 250

 acatgaacca ctgctactcc cgcctgcggg aactggtacc cggagtcccg 300

 agaggcactc agcttagcca ggtggaaatc ctacagcgcg tcatcgacta 350

 cattctcgac ctgcaggtag tcctggccga gccagcccct ggaccccctg 400

 atggccccca ccttcccatc cagacagccg agctcgctcc ggaacttgtc 450

 atctccaacg acaaaaggag cttttgccac tgactcggcc gtgtcctgac 500

 acctccagaa cgcaggtgct ggcgcccgtt ctgcctggga ccccgggaac 550

 ctctcctgcc ggaagccgga cggcagggat gggccccaac ttcgccctgc 600

 ccacttgact tcaccaaatc ccttcctgga gactgaacct ggtgctcagg 650

 agcgaaggac tgtgaacttg tggcctgaag agccagagct agctctggcc 700

 accagctggg cgacgtcacc ctgctcccac cccaccccaa gttctaaggt 750

 cttttcagag cgtggaggtg tggaaggagt ggctgctctc caaactatgc 800

 caaggcggcg gcagagctgg tcttctggtc tccttggaga aaggttctgt 850

 tgccctgatt tatgaactct ataatagagt atataggttt tgtacctttt 900

 ttacaggaag gtgactttct gtaacaatgc gatgtatatt aaacttttta 950

 taaaagttaa cattttgcat aataaacgat tt 982

<210> 1680
<211> 148
<212> PRT
<213> Homo sapien

<400> 1680
 Met Asp Pro Ala Pro Arg Glu Pro His Ser Thr Ser Leu Leu Leu
   1               5                  10                  15

 Val Phe Phe Leu Phe Gly Ala Pro Leu Asp Ser Leu Pro Ser Met
                  20                  25                  30

 Lys Ala Leu Ser Pro Val Arg Gly Cys Tyr Glu Ala Val Cys Cys
                  35                  40                  45

 Leu Ser Glu Arg Ser Leu Ala Ile Ala Arg Gly Arg Gly Lys Gly
                  50                  55                  60

 Pro Ala Ala Glu Glu Pro Leu Ser Leu Leu Asp Asp Met Asn His
                  65                  70                  75

 Cys Tyr Ser Arg Leu Arg Glu Leu Val Pro Gly Val Pro Arg Gly
                  80                  85                  90

 Thr Gln Leu Ser Gln Val Glu Ile Leu Gln Arg Val Ile Asp Tyr
                  95                 100                 105

 Ile Leu Asp Leu Gln Val Val Leu Ala Glu Pro Ala Pro Gly Pro
                 110                 115                 120

 Pro Asp Gly Pro His Leu Pro Ile Gln Thr Ala Glu Leu Ala Pro
                 125                 130                 135

 Glu Leu Val Ile Ser Asn Asp Lys Arg Ser Phe Cys His
                 140                 145

<210> 1681
<211> 10211
<212> DNA
<213> Homo sapien

<400> 1681
 gagaggtcgt tttcccgtcc ccgagagcaa gtttatttac aaatgttgga 50

 gtaataaaga aggcagaaca aaatgagctg ggctttggaa gaatggaaag 100

 aagggctgcc tacaagagct cttcagaaaa ttcaagagct tgaaggacag 150

 cttgacaaac tgaagaagga aaagcagcaa aggcagtttc agcttgacag 200

 tctcgaggct gcgcctcaga agcaaacaca gaaggttgaa aatgaaaaaa 250

 ccgagggtac aaacctgaaa agggagaatc aaagattgat ggaaatatgt 300

 gaaagtctgg agaaaactaa gcagaagatt tctcatgaac ttcaagtcaa 350

 ggagtcacaa gtgaatttcc aggaaggaca actgaattca ggcaaaaaac 400

 aaatagaaaa actggaacag gaacttaaaa ggtgtaaatc tgagcttgaa 450

 agaagccaac aagctgcgca gtctgcagat gtctctctga atccatgcaa 500

 tacaccacaa aaaattttta caactccact aacaccaagt caatattata 550

 gtggttccaa gtatgaagat ctaaaagaaa aatataataa agaggttgaa 600

 gaacgaaaaa gattagaggc agaggttaaa gccttgcagg ctaaaaaagc 650

 aagccagact cttccacaag ccaccatgaa tcaccgcgac attgcccggc 700

 atcaggcttc atcatctgtg ttctcatggc agcaagagaa gaccccaagt 750

 catctttcat ctaattctca aagaactcca attaggagag atttctctgc 800

 atcttacttt tctggggaac aagaggtgac tccaagtcga tcaactttgc 850

 aaatagggaa aagagatgct aatagcagtt tctttgacaa ttctagcagt 900

 cctcatcttt tggatcaatt aaaagcgcag aatcaagagc taagaaacaa 950

 gattaatgag ttggaactac gcctgcaagg acatgaaaaa gaaatgaaag 1000

 gccaagtgaa taagtttcaa gaactccaac tccaactgga gaaagcaaaa 1050

 gtggaattaa ttgaaaaaga gaaagttttg aacaaatgta gggatgaact 1100

 agtgagaaca acagcacaat acgaccaggc gtcaaccaag tatactgcat 1150

 tggaacaaaa actgaaaaaa ttgacggaag atttgagttg tcagcgacaa 1200

 aatgcagaaa gtgccagatg ttctctggaa cagaaaatta aggaaaaaga 1250

 aaaggagttt caagaggagc tctcccgtca acagcgttct ttccaaacac 1300

 tggaccagga gtgcatccag atgaaggcca gactcaccca ggagttacag 1350

 caagccaaga atatgcacaa cgtcctgcag gctgaactgg ataaactcac 1400

 atcagtaaag caacagctag aaaacaattt ggaagagttt aagcaaaagt 1450

 tgtgcagagc tgaacaggcg ttccaggcga gtcagatcaa ggagaatgag 1500

 ctgaggagaa gcatggagga aatgaagaag gaaaacaacc tccttaagag 1550

 tcactctgag caaaaggcca gagaagtctg ccacctggag gcagaactca 1600

 agaacatcaa acagtgttta aatcagagcc agaattttgc agaagaaatg 1650

 aaagcgaaga atacctctca ggaaaccatg ttaagagatc ttcaagaaaa 1700

 aataaatcag caagaaaact ccttgacttt agaaaaactg aagcttgctg 1750

 tggctgatct ggaaaagcag cgagattgtt ctcaagacct tttgaagaaa 1800

 agagaacatc acattgaaca acttaatgat aagttaagca agacagagaa 1850

 agagtccaaa gccttgctga gtgctttaga gttaaaaaag aaagaatatg 1900

 aattgaaaga agagaaaact ctgttttctt gttggaaaag tgaaaacgaa 1950

 aaacttttaa ctcagatgga atcagaaaag gaaaacttgc agagtaaaat 2000

 taatcacttg gaaacttgtc tgaagacaca gcaaataaaa agtcatgaat 2050

 acaacgagag agtaagaacg ctggagatgg acagagaaaa cctaagtgtc 2100

 gagatcagaa accttcacaa cgtgttagac agtaagtcag tggaggtaga 2150

 gacccagaaa ctagcttata tggagctaca gcagaaagct gagttctcag 2200

 atcagaaaca tcagaaggaa atagaaaata tgtgtttgaa gacttctcag 2250

 cttactgggc aagttgaaga tctagaacac aagcttcagt tactgtcaaa 2300

 tgaaataatg gacaaagacc ggtgttacca agacttgcat gccgaatatg 2350

 agagcctcag ggatctgcta aaatccaaag atgcttctct ggtgacaaat 2400

 gaagatcatc agagaagtct tttggctttt gatcagcagc ctgccatgca 2450

 tcattccttt gcaaatataa ttggagaaca aggaagcatg ccttcagaga 2500

 ggagtgaatg tcgtttagaa gcagaccaaa gtccgaaaaa ttctgccatc 2550

 ctacaaaata gagttgattc acttgaattt tcattagagt ctcaaaaaca 2600

 gatgaactca gacctgcaaa agcagtgtga agagttggtg caaatcaaag 2650

 gagaaataga agaaaatctc atgaaagcag aacagatgca tcaaagtttt 2700

 gtggctgaaa caagtcagcg cattagtaag ttacaggaag acacttctgc 2750

 tcaccagaat gttgttgctg aaaccttaag tgcccttgag aacaaggaaa 2800

 aagagctgca acttttaaat gataaggtag aaactgagca ggcagagatt 2850

 caagaattaa aaaagagcaa ccatctactt gaagactctc taaaggagct 2900

 acaactttta tccgaaaccc taagcttgga gaagaaagaa atgagttcca 2950

 tcatttctct aaataaaagg gaaattgaag agctgaccca agagaatggg 3000

 actcttaagg aaattaatgc atccttaaat caagagaaga tgaacttaat 3050

 ccagaaaagt gagagttttg caaactatat agatgaaagg gagaaaagca 3100

 tttcagagtt atctgatcag tacaagcaag aaaaacttat tttactacaa 3150

 agatgtgaag aaaccggaaa tgcatatgag gatcttagtc aaaaatacaa 3200

 agcagcacag gaaaagaatt ctaaattaga atgcttgcta aatgaatgca 3250

 ctagtctttg tgaaaatagg aaaaatgagt tggaacagct aaaggaagca 3300

 tttgcaaagg aacaccaaga attcttaaca aaattagcat ttgctgaaga 3350

 aagaaatcag aatctgatgc tagagttgga gacagtgcag caagctctga 3400

 gatctgagat gacagataac caaaacaatt ctaagagcga ggctggtggt 3450

 ttaaagcaag aaatcatgac tttaaaggaa gaacaaaaca aaatgcaaaa 3500

 ggaagttaat gacttattac aagagaatga acagctgatg aaggtaatga 3550

 agactaaaca tgaatgtcaa aatctagaat cagaaccaat taggaactct 3600

 gtgaaagaaa gagagagtga gagaaatcaa tgtaatttta aacctcagat 3650

 ggatcttgaa gttaaagaaa tttctctaga tagttataat gcgcagttgg 3700

 tgcaattaga agctatgcta agaaataagg aattaaaact tcaggaaagt 3750

 gagaaggaga aggagtgcct gcagcatgaa ttacagacaa ttagaggaga 3800

 tcttgaaacc agcaatttgc aagacatgca gtcacaagaa attagtggcc 3850

 ttaaagactg tgaaatagat gcggaagaaa agtatatttc agggcctcat 3900

 gagttgtcaa caagtcaaaa cgacaatgca caccttcagt gctctctgca 3950

 aacaacaatg aacaagctga atgagctaga gaaaatatgt gaaatactgc 4000

 aggctgaaaa gtatgaactc gtaactgagc tgaatgattc aaggtcagaa 4050

 tgtatcacag caactaggaa aatggcagaa gaggtaggga aactactaaa 4100

 tgaagttaaa atattaaatg atgacagtgg tcttctccat ggtgagttag 4150

 tggaagacat accaggaggt gaatttggtg aacaaccaaa tgaacagcac 4200

 cctgtgtctt tggctccatt ggacgagagt aattcctacg agcacttgac 4250

 attgtcagac aaagaagttc aaatgcactt tgccgaattg caagagaaat 4300

 tcttatcttt acaaagtgaa cacaaaattt tacatgatca gcactgtcag 4350

 atgagctcta aaatgtcaga gctgcagacc tatgttgact cattaaaggc 4400

 cgaaaatttg gtcttgtcaa cgaatctgag aaactttcaa ggtgacttgg 4450

 tgaaggagat gcagctgggc ttggaggagg ggctcgttcc atccctgtca 4500

 tcctcttgtg tgcctgacag ctctagtctt agcagtttgg gagactcctc 4550

 cttttacaga gctcttttag aacagacagg agatatgtct cttttgagta 4600

 atttagaagg ggctgtttca gcaaaccagt gcagtgtaga tgaagtattt 4650

 tgcagcagtc tgcaggagga gaatctgacc aggaaagaaa ccccttcggc 4700

 cccagcgaag ggtgttgaag agcttgagtc cctctgtgag gtgtaccggc 4750

 agtccctcga gaagctagaa gagaaaatgg aaagtcaagg gattatgaaa 4800

 aataaggaaa ttcaagagct cgagcagtta ttaagttctg aaaggcaaga 4850

 gcttgactgc cttaggaagc agtatttgtc agaaaatgaa cagtggcaac 4900

 agaagctgac aagcgtgact ctggagatgg agtccaagtt ggcggcagaa 4950

 aagaaacaga cggaacaact gtcacttgag ctggaagtag cacgactcca 5000

 gctacaaggt ctggacttaa gttctcggtc tttgcttggc atcgacacag 5050

 aagatgctat tcaaggccga aatgagagct gtgacatatc aaaagaacat 5100

 acttcagaaa ctacagaaag aacaccaaag catgatgttc atcagatttg 5150

 tgataaagat gctcagcagg acctcaatct agacattgag aaaataactg 5200

 agactggtgc attgaaaccc acaggagagt gctctgggga acagtcccca 5250

 gataccaatt atgagcctcc aggggaagat aaaacccagg gctcttcaga 5300

 atgcatttct gaattgtcat tttctggtcc taatgctttg gtacctatgg 5350

 atttcctggg gaatcaggaa gatatccata atcttcaact gcgggtaaaa 5400

 gagacatcaa atgagaattt gagattactt catgtgatag aggaccgtga 5450

 cagaaaagtt gaaagtttgc taaatgaaat gaaagaatta gactcaaaac 5500

 tccatttaca ggaggtacaa ctaatgacca aaattgaagc atgcatagaa 5550

 ttggaaaaaa tagttgggga acttaagaaa gaaaactcag atttaagtga 5600

 aaaattggaa tatttttctt gtgatcacca ggagttactc cagagagtag 5650

 aaacttctga aggcctcaat tctgatttag aaatgcatgc agataaatca 5700

 tcacgtgaag atattggaga taatgtggcc aaggtgaatg acagctggaa 5750

 ggagagattt cttgatgtgg aaaatgagct gagtaggatc agatcggaga 5800

 aagctagcat tgagcatgaa gccctctacc tggaggctga cttagaggta 5850

 gttcaaacag agaagctatg tttagaaaaa gacaatgaaa ataagcagaa 5900

 ggttattgtc tgccttgaag aagaactctc agtggtcaca agtgagagaa 5950

 accagcttcg tggagaatta gatactatgt caaaaaaaac cacggcactg 6000

 gatcagttgt ctgaaaaaat gaaggagaaa acacaagagc ttgagtctca 6050

 tcaaagtgag tgtctccatt gcattcaggt ggcagaggca gaggtgaagg 6100

 aaaagacgga actccttcag actttgtcct ctgatgtgag tgagctgtta 6150

 aaagacaaaa ctcatctcca ggaaaagctg cagagtttgg aaaaggactc 6200

 acaggcactg tctttgacaa aatgtgagct ggaaaaccaa attgcacaac 6250

 tgaataaaga gaaagaattg cttgtcaagg aatctgaaag cctgcaggcc 6300

 agactgagtg aatcagatta tgaaaagctg aatgtctcca aggccttgga 6350

 ggccgcactg gtggagaaag gtgagttcgc attgaggctg agctcaacac 6400

 aggaggaagt gcatcagctg agaagaggca tcgagaaact gagagttcgc 6450

 attgaggccg atgaaaagaa gcagctgcac atcgcagaga aactgaaaga 6500

 acgcgagcgg gagaatgatt cacttaagga taaagttgag aaccttgaaa 6550

 gggaattgca gatgtcagaa gaaaaccagg agctagtgat tcttgatgcc 6600

 gagaattcca aagcagaagt agagactcta aaaacacaaa tagaagagat 6650

 ggccagaagc ctgaaagttt ttgaattaga ccttgtcacg ttaaggtctg 6700

 aaaaagaaaa tctgacaaaa caaatacaag aaaaacaagg tcagttgtca 6750

 gaactagaca agttactctc ttcatttaaa agtctgttag aagaaaagga 6800

 gcaagcagag atacagatca aagaagaatc taaaactgca gtggagatgc 6850

 ttcagaatca gttaaaggag ctaaatgagg cagtagcagc cttgtgtggt 6900

 gaccaagaaa ttatgaaggc cacagaacag agtctagacc caccaataga 6950

 ggaagagcat cagctgagaa atagcattga aaagctgaga gcccgcctag 7000

 aagctgatga aaagaagcag ctctgtgtct tacaacaact gaaggaaagt 7050

 gagcatcatg cagatttact taagggtaga gtggagaacc ttgaaagaga 7100

 gctagagata gccaggacaa accaagagca tgcagctctt gaggcagaga 7150

 attccaaagg agaggtagag accctaaaag caaaaataga agggatgacc 7200

 caaagtctga gaggtctgga attagatgtt gttactataa ggtcagaaaa 7250

 agaaaatctg acaaatgaat tacaaaaaga gcaagagcga atatctgaat 7300

 tagaaataat aaattcatca tttgaaaata ttttgcaaga aaaagagcaa 7350

 gagaaagtac agatgaaaga aaaatcaagc actgccatgg agatgcttca 7400

 aacacaatta aaagagctca atgagagagt ggcagccctg cataatgacc 7450

 aagaagcctg taaggccaaa gagcagaatc ttagtagtca agtagagtgt 7500

 cttgaacttg agaaggctca gttgctacaa ggccttgatg aggccaaaaa 7550

 taattatatt gttttgcaat cttcagtgaa tggcctcatt caagaagtag 7600

 aagatggcaa gcagaaactg gagaagaagg atgaagaaat cagtagactg 7650

 aaaaatcaaa ttcaagacca agagcagctt gtctctaaac tgtcccaggt 7700

 ggaaggagag caccaacttt ggaaggagca aaacttagaa ctgagaaatc 7750

 tgacagtgga attggagcag aagatccaag tgctacaatc caaaaatgcc 7800

 tctttgcagg acacattaga agtgctgcag agttcttaca agaatctaga 7850

 gaatgagctt gaattgacaa aaatggacaa aatgtccttt gttgaaaaag 7900

 taaacaaaat gactgcaaag gaaactgagc tgcagaggga aatgcatgag 7950

 atggcacaga aaacagcaga gctgcaagaa gaactcagtg gagagaaaaa 8000

 taggctagct ggagagttgc agttactgtt ggaagaaata aagagcagca 8050

 aagatcaatt gaaggagctc acactagaaa atagtgaatt gaagaagagc 8100

 ctagattgca tgcacaaaga ccaggtggaa aaggaaggga aagtgagaga 8150

 ggaaatagct gaatatcagc tacggcttca tgaagctgaa aagaaacacc 8200

 aggctttgct tttggacaca aacaaacagt atgaagtaga aatccagaca 8250

 taccgagaga aattgacttc taaagaagaa tgtctcagtt cacagaagct 8300

 ggagatagac cttttaaagt ctagtaaaga agagctcaat aattcattga 8350

 aagctactac tcagattttg gaagaattga agaaaaccaa gatggacaat 8400

 ctaaaatatg taaatcagtt gaagaaggaa aatgaacgtg cccaggggaa 8450

 aatgaagttg ttgatcaaat cctgtaaaca gctggaagag gaaaaggaga 8500

 tactgcagaa agaactctct caacttcaag ctgcacagga gaagcagaaa 8550

 acaggtactg ttatggatac caaggtcgat gaattaacaa ctgagatcaa 8600

 agaactgaaa gaaactcttg aagaaaaaac caaggaggca gatgaatact 8650

 tggataagta ctgttccttg cttataagcc atgaaaagtt agagaaagct 8700

 aaagagatgt tagagacaca agtggcccat ctgtgttcac agcaatctaa 8750

 acaagattcc cgagggtctc ctttgctagg tccagttgtt ccaggaccat 8800

 ctccaatccc ttctgttact gaaaagaggt tatcatctgg ccaaaataaa 8850

 gcttcaggca agaggcaaag atccagtgga atatgggaga atggtggagg 8900

 accaacacct gctaccccag agagcttttc taaaaaaagc aagaaagcag 8950

 tcatgagtgg tattcaccct gcagaagaca cggaaggtac tgagtttgag 9000

 ccagagggac ttccagaagt tgtaaagaaa gggtttgctg acatcccgac 9050

 aggaaagact agcccatata tcctgcgaag aacaaccatg gcaactcgga 9100

 ccagcccccg cctggctgca cagaagttag cgctatcccc actgagtctc 9150

 ggcaaagaaa atcttgcaga gtcctccaaa ccaacagctg gtggcagcag 9200

 atcacaaaag gtcaaagttg ctcagcggag cccagtagat tcaggcacca 9250

 tcctccgaga acccaccacg aaatccgtcc cagtcaataa tcttcctgag 9300

 agaagtccga ctgacagccc cagagagggc ctgagggtca agcgaggccg 9350

 acttgtcccc agccccaaag ctggactgga gtccaagggc agtgagaact 9400

 gtaaggtcca gtgaaggcac tttgtgtgtc agtacccctg ggaggtgcca 9450

 gtcattgaat agataaggct gtgcctacag gacttctctt tagtcagggc 9500

 atgctttatt agtgaggaga aaacaattcc ttagaagtct taaatatatt 9550

 gtactcttta gatctcccat gtgtaggtat tgaaaaagtt tggaagcact 9600

 gatcacctgt tagcattgcc attcctctac tgcaatgtaa atagtataaa 9650

 gctatgtata taaagctttt tggtaatatg ttacaattaa aatgacaagc 9700

 actatatcac aatctctgtt tgtatgtggg ttttacacta aaaaaatgca 9750

 aaacacattt tattcttcta attaacagct cctaggaaaa tgtagacttt 9800

 tgctttatga tattctatct gtagtatgag gcatggaata gttttgtatc 9850

 gggaatttct cagagctgag taaaatgaag gaaaagcatg ttatgtgttt 9900

 ttaaggaaaa tgtgcacaca tatacatgta ggagtgttta tctttctctt 9950

 acaatctgtt ttagacatct ttgcttatga aacctgtaca tatgtgtgtg 10000

 tgggtatgtg tttatttcca gtgagggctg caggcttcct agaggtgtgc 10050

 tataccatgc gtctgtcgtt gtgctttttt ctgtttttag accaattttt 10100

 tacagttctt tggtaagcat tgtcgtatct ggtgatggat taacatatag 10150

 cctttgtttt ctaataaaat agtcgccttc gttttctgta aaaaaaaaaa 10200

 aaaaaaaaaa a 10211

<210> 1682
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1682
 Met Ser Trp Ala Leu Glu Glu Trp Lys Glu Gly Leu Pro Thr Arg
   1               5                  10                  15

 Ala Leu Gln Lys Ile Gln Glu Leu Glu Gly Gln Leu Asp Lys Leu
                  20                  25                  30

 Lys Lys Glu Lys Gln Gln Arg Gln Phe Gln Leu Asp Ser Leu Glu
                  35                  40                  45

 Ala Ala Pro Gln Lys Gln Thr Gln Lys Val Glu Asn Glu Lys Thr
                  50                  55                  60

 Glu Gly Thr Asn Leu Lys Arg Glu Asn Gln Arg Leu Met Glu Ile
                  65                  70                  75

 Cys Glu Ser Leu Glu Lys Thr Lys Gln Lys Ile Ser His Glu Leu
                  80                  85                  90

 Gln Val Lys Glu Ser Gln Val Asn Phe Gln Glu Gly Gln Leu Asn
                  95                 100                 105

 Ser Gly Lys Lys Gln Ile Glu Lys Leu Glu Gln Glu Leu Lys Arg
                 110                 115                 120

 Cys Lys Ser Glu Leu Glu Arg Ser Gln Gln Ala Ala Gln Ser Ala
                 125                 130                 135

 Asp Val Ser Leu Asn Pro Cys Asn Thr Pro Gln Lys Ile Phe Thr
                 140                 145                 150

 Thr Pro Leu Thr Pro Ser Gln Tyr Tyr Ser Gly Ser Lys Tyr Glu
                 155                 160                 165

 Asp Leu Lys Glu Lys Tyr Asn Lys Glu Val Glu Glu Arg Lys Arg
                 170                 175                 180

 Leu Glu Ala Glu Val Lys Ala Leu Gln Ala Lys Lys Ala Ser Gln
                 185                 190                 195

 Thr Leu Pro Gln Ala Thr Met Asn His Arg Asp Ile Ala Arg His
                 200                 205                 210

 Gln Ala Ser Ser Ser Val Phe Ser Trp Gln Gln Glu Lys Thr Pro
                 215                 220                 225

 Ser His Leu Ser Ser Asn Ser Gln Arg Thr Pro Ile Arg Arg Asp
                 230                 235                 240

 Phe Ser Ala Ser Tyr Phe Ser Gly Glu Gln Glu Val Thr Pro Ser
                 245                 250                 255

 Arg Ser Thr Leu Gln Ile Gly Lys Arg Asp Ala Asn Ser Ser Phe
                 260                 265                 270

 Phe Asp Asn Ser Ser Ser Pro His Leu Leu Asp Gln Leu Lys Ala
                 275                 280                 285

 Gln Asn Gln Glu Leu Arg Asn Lys Ile Asn Glu Leu Glu Leu Arg
                 290                 295                 300

 Leu Gln Gly His Glu Lys Glu Met Lys Gly Gln Val Asn Lys Phe
                 305                 310                 315

 Gln Glu Leu Gln Leu Gln Leu Glu Lys Ala Lys Val Glu Leu Ile
                 320                 325                 330

 Glu Lys Glu Lys Val Leu Asn Lys Cys Arg Asp Glu Leu Val Arg
                 335                 340                 345

 Thr Thr Ala Gln Tyr Asp Gln Ala Ser Thr Lys Tyr Thr Ala Leu
                 350                 355                 360

 Glu Gln Lys Leu Lys Lys Leu Thr Glu Asp Leu Ser Cys Gln Arg
                 365                 370                 375

 Gln Asn Ala Glu Ser Ala Arg Cys Ser Leu Glu Gln Lys Ile Lys
                 380                 385                 390

 Glu Lys Glu Lys Glu Phe Gln Glu Glu Leu Ser Arg Gln Gln Arg
                 395                 400                 405

 Ser Phe Gln Thr Leu Asp Gln Glu Cys Ile Gln Met Lys Ala Arg
                 410                 415                 420

 Leu Thr Gln Glu Leu Gln Gln Ala Lys Asn Met His Asn Val Leu
                 425                 430                 435

 Gln Ala Glu Leu Asp Lys Leu Thr Ser Val Lys Gln Gln Leu Glu
                 440                 445                 450

 Asn Asn Leu Glu Glu Phe Lys Gln Lys Leu Cys Arg Ala Glu Gln
                 455                 460                 465

 Ala Phe Gln Ala Ser Gln Ile Lys Glu Asn Glu Leu Arg Arg Ser
                 470                 475                 480

 Met Glu Glu Met Lys Lys Glu Asn Asn Leu Leu Lys Ser His Ser
                 485                 490                 495

 Glu Gln Lys Ala Arg Glu Val Cys His Leu Glu Ala Glu Leu Lys
                 500                 505                 510

 Asn Ile Lys Gln Cys Leu Asn Gln Ser Gln Asn Phe Ala Glu Glu
                 515                 520                 525

 Met Lys Ala Lys Asn Thr Ser Gln Glu Thr Met Leu Arg Asp Leu
                 530                 535                 540

 Gln Glu Lys Ile Asn Gln Gln Glu Asn Ser Leu Thr Leu Glu Lys
                 545                 550                 555

 Leu Lys Leu Ala Val Ala Asp Leu Glu Lys Gln Arg Asp Cys Ser
                 560                 565                 570

 Gln Asp Leu Leu Lys Lys Arg Glu His His Ile Glu Gln Leu Asn
                 575                 580                 585

 Asp Lys Leu Ser Lys Thr Glu Lys Glu Ser Lys Ala Leu Leu Ser
                 590                 595                 600

 Ala Leu Glu Leu Lys Lys Lys Glu Tyr Glu Leu Lys Glu Glu Lys
                 605                 610                 615

 Thr Leu Phe Ser Cys Trp Lys Ser Glu Asn Glu Lys Leu Leu Thr
                 620                 625                 630

 Gln Met Glu Ser Glu Lys Glu Asn Leu Gln Ser Lys Ile Asn His
                 635                 640                 645

 Leu Glu Thr Cys Leu Lys Thr Gln Gln Ile Lys Ser His Glu Tyr
                 650                 655                 660

 Asn Glu Arg Val Arg Thr Leu Glu Met Asp Arg Glu Asn Leu Ser
                 665                 670                 675

 Val Glu Ile Arg Asn Leu His Asn Val Leu Asp Ser Lys Ser Val
                 680                 685                 690

 Glu Val Glu Thr Gln Lys Leu Ala Tyr Met Glu Leu Gln Gln Lys
                 695                 700                 705

 Ala Glu Phe Ser Asp Gln Lys His Gln Lys Glu Ile Glu Asn Met
                 710                 715                 720

 Cys Leu Lys Thr Ser Gln Leu Thr Gly Gln Val Glu Asp Leu Glu
                 725                 730                 735

 His Lys Leu Gln Leu Leu Ser Asn Glu Ile Met Asp Lys Asp Arg
                 740                 745                 750

 Cys Tyr Gln Asp Leu His Ala Glu Tyr Glu Ser Leu Arg Asp Leu
                 755                 760                 765

 Leu Lys Ser Lys Asp Ala Ser Leu Val Thr Asn Glu Asp His Gln
                 770                 775                 780

 Arg Ser Leu Leu Ala Phe Asp Gln Gln Pro Ala Met His His Ser
                 785                 790                 795

 Phe Ala Asn Ile Ile Gly Glu Gln Gly Ser Met Pro Ser Glu Arg
                 800                 805                 810

 Ser Glu Cys Arg Leu Glu Ala Asp Gln Ser Pro Lys Asn Ser Ala
                 815                 820                 825

 Ile Leu Gln Asn Arg Val Asp Ser Leu Glu Phe Ser Leu Glu Ser
                 830                 835                 840

 Gln Lys Gln Met Asn Ser Asp Leu Gln Lys Gln Cys Glu Glu Leu
                 845                 850                 855

 Val Gln Ile Lys Gly Glu Ile Glu Glu Asn Leu Met Lys Ala Glu
                 860                 865                 870

 Gln Met His Gln Ser Phe Val Ala Glu Thr Ser Gln Arg Ile Ser
                 875                 880                 885

 Lys Leu Gln Glu Asp Thr Ser Ala His Gln Asn Val Val Ala Glu
                 890                 895                 900

 Thr Leu Ser Ala Leu Glu Asn Lys Glu Lys Glu Leu Gln Leu Leu
                 905                 910                 915

 Asn Asp Lys Val Glu Thr Glu Gln Ala Glu Ile Gln Glu Leu Lys
                 920                 925                 930

 Lys Ser Asn His Leu Leu Glu Asp Ser Leu Lys Glu Leu Gln Leu
                 935                 940                 945

 Leu Ser Glu Thr Leu Ser Leu Glu Lys Lys Glu Met Ser Ser Ile
                 950                 955                 960

 Ile Ser Leu Asn Lys Arg Glu Ile Glu Glu Leu Thr Gln Glu Asn
                 965                 970                 975

 Gly Thr Leu Lys Glu Ile Asn Ala Ser Leu Asn Gln Glu Lys Met
                 980                 985                 990

 Asn Leu Ile Gln Lys Ser Glu Ser Phe Ala Asn Tyr Ile Asp Glu
                 995                1000                1005

 Arg Glu Lys Ser Ile Ser Glu Leu Ser Asp Gln Tyr Lys Gln Glu
                1010                1015                1020

 Lys Leu Ile Leu Leu Gln Arg Cys Glu Glu Thr Gly Asn Ala Tyr
                1025                1030                1035

 Glu Asp Leu Ser Gln Lys Tyr Lys Ala Ala Gln Glu Lys Asn Ser
                1040                1045                1050

 Lys Leu Glu Cys Leu Leu Asn Glu Cys Thr Ser Leu Cys Glu Asn
                1055                1060                1065

 Arg Lys Asn Glu Leu Glu Gln Leu Lys Glu Ala Phe Ala Lys Glu
                1070                1075                1080

 His Gln Glu Phe Leu Thr Lys Leu Ala Phe Ala Glu Glu Arg Asn
                1085                1090                1095

 Gln Asn Leu Met Leu Glu Leu Glu Thr Val Gln Gln Ala Leu Arg
                1100                1105                1110

 Ser Glu Met Thr Asp Asn Gln Asn Asn Ser Lys Ser Glu Ala Gly
                1115                1120                1125

 Gly Leu Lys Gln Glu Ile Met Thr Leu Lys Glu Glu Gln Asn Lys
                1130                1135                1140

 Met Gln Lys Glu Val Asn Asp Leu Leu Gln Glu Asn Glu Gln Leu
                1145                1150                1155

 Met Lys Val Met Lys Thr Lys His Glu Cys Gln Asn Leu Glu Ser
                1160                1165                1170

 Glu Pro Ile Arg Asn Ser Val Lys Glu Arg Glu Ser Glu Arg Asn
                1175                1180                1185

 Gln Cys Asn Phe Lys Pro Gln Met Asp Leu Glu Val Lys Glu Ile
                1190                1195                1200

 Ser Leu Asp Ser Tyr Asn Ala Gln Leu Val Gln Leu Glu Ala Met
                1205                1210                1215

 Leu Arg Asn Lys Glu Leu Lys Leu Gln Glu Ser Glu Lys Glu Lys
                1220                1225                1230

 Glu Cys Leu Gln His Glu Leu Gln Thr Ile Arg Gly Asp Leu Glu
                1235                1240                1245

 Thr Ser Asn Leu Gln Asp Met Gln Ser Gln Glu Ile Ser Gly Leu
                1250                1255                1260

 Lys Asp Cys Glu Ile Asp Ala Glu Glu Lys Tyr Ile Ser Gly Pro
                1265                1270                1275

 His Glu Leu Ser Thr Ser Gln Asn Asp Asn Ala His Leu Gln Cys
                1280                1285                1290

 Ser Leu Gln Thr Thr Met Asn Lys Leu Asn Glu Leu Glu Lys Ile
                1295                1300                1305

 Cys Glu Ile Leu Gln Ala Glu Lys Tyr Glu Leu Val Thr Glu Leu
                1310                1315                1320

 Asn Asp Ser Arg Ser Glu Cys Ile Thr Ala Thr Arg Lys Met Ala
                1325                1330                1335

 Glu Glu Val Gly Lys Leu Leu Asn Glu Val Lys Ile Leu Asn Asp
                1340                1345                1350

 Asp Ser Gly Leu Leu His Gly Glu Leu Val Glu Asp Ile Pro Gly
                1355                1360                1365

 Gly Glu Phe Gly Glu Gln Pro Asn Glu Gln His Pro Val Ser Leu
                1370                1375                1380

 Ala Pro Leu Asp Glu Ser Asn Ser Tyr Glu His Leu Thr Leu Ser
                1385                1390                1395

 Asp Lys Glu Val Gln Met His Phe Ala Glu Leu Gln Glu Lys Phe
                1400                1405                1410

 Leu Ser Leu Gln Ser Glu His Lys Ile Leu His Asp Gln His Cys
                1415                1420                1425

 Gln Met Ser Ser Lys Met Ser Glu Leu Gln Thr Tyr Val Asp Ser
                1430                1435                1440

 Leu Lys Ala Glu Asn Leu Val Leu Ser Thr Asn Leu Arg Asn Phe
                1445                1450                1455

 Gln Gly Asp Leu Val Lys Glu Met Gln Leu Gly Leu Glu Glu Gly
                1460                1465                1470

 Leu Val Pro Ser Leu Ser Ser Ser Cys Val Pro Asp Ser Ser Ser
                1475                1480                1485

 Leu Ser Ser Leu Gly Asp Ser Ser Phe Tyr Arg Ala Leu Leu Glu
                1490                1495                1500

 Gln Thr Gly Asp Met Ser Leu Leu Ser Asn Leu Glu Gly Ala Val
                1505                1510                1515

 Ser Ala Asn Gln Cys Ser Val Asp Glu Val Phe Cys Ser Ser Leu
                1520                1525                1530

 Gln Glu Glu Asn Leu Thr Arg Lys Glu Thr Pro Ser Ala Pro Ala
                1535                1540                1545

 Lys Gly Val Glu Glu Leu Glu Ser Leu Cys Glu Val Tyr Arg Gln
                1550                1555                1560

 Ser Leu Glu Lys Leu Glu Glu Lys Met Glu Ser Gln Gly Ile Met
                1565                1570                1575

 Lys Asn Lys Glu Ile Gln Glu Leu Glu Gln Leu Leu Ser Ser Glu
                1580                1585                1590

 Arg Gln Glu Leu Asp Cys Leu Arg Lys Gln Tyr Leu Ser Glu Asn
                1595                1600                1605

 Glu Gln Trp Gln Gln Lys Leu Thr Ser Val Thr Leu Glu Met Glu
                1610                1615                1620

 Ser Lys Leu Ala Ala Glu Lys Lys Gln Thr Glu Gln Leu Ser Leu
                1625                1630                1635

 Glu Leu Glu Val Ala Arg Leu Gln Leu Gln Gly Leu Asp Leu Ser
                1640                1645                1650

 Ser Arg Ser Leu Leu Gly Ile Asp Thr Glu Asp Ala Ile Gln Gly
                1655                1660                1665

 Arg Asn Glu Ser Cys Asp Ile Ser Lys Glu His Thr Ser Glu Thr
                1670                1675                1680

 Thr Glu Arg Thr Pro Lys His Asp Val His Gln Ile Cys Asp Lys
                1685                1690                1695

 Asp Ala Gln Gln Asp Leu Asn Leu Asp Ile Glu Lys Ile Thr Glu
                1700                1705                1710

 Thr Gly Ala Leu Lys Pro Thr Gly Glu Cys Ser Gly Glu Gln Ser
                1715                1720                1725

 Pro Asp Thr Asn Tyr Glu Pro Pro Gly Glu Asp Lys Thr Gln Gly
                1730                1735                1740

 Ser Ser Glu Cys Ile Ser Glu Leu Ser Phe Ser Gly Pro Asn Ala
                1745                1750                1755

 Leu Val Pro Met Asp Phe Leu Gly Asn Gln Glu Asp Ile His Asn
                1760                1765                1770

 Leu Gln Leu Arg Val Lys Glu Thr Ser Asn Glu Asn Leu Arg Leu
                1775                1780                1785

 Leu His Val Ile Glu Asp Arg Asp Arg Lys Val Glu Ser Leu Leu
                1790                1795                1800

 Asn Glu Met Lys Glu Leu Asp Ser Lys Leu His Leu Gln Glu Val
                1805                1810                1815

 Gln Leu Met Thr Lys Ile Glu Ala Cys Ile Glu Leu Glu Lys Ile
                1820                1825                1830

 Val Gly Glu Leu Lys Lys Glu Asn Ser Asp Leu Ser Glu Lys Leu
                1835                1840                1845

 Glu Tyr Phe Ser Cys Asp His Gln Glu Leu Leu Gln Arg Val Glu
                1850                1855                1860

 Thr Ser Glu Gly Leu Asn Ser Asp Leu Glu Met His Ala Asp Lys
                1865                1870                1875

 Ser Ser Arg Glu Asp Ile Gly Asp Asn Val Ala Lys Val Asn Asp
                1880                1885                1890

 Ser Trp Lys Glu Arg Phe Leu Asp Val Glu Asn Glu Leu Ser Arg
                1895                1900                1905

 Ile Arg Ser Glu Lys Ala Ser Ile Glu His Glu Ala Leu Tyr Leu
                1910                1915                1920

 Glu Ala Asp Leu Glu Val Val Gln Thr Glu Lys Leu Cys Leu Glu
                1925                1930                1935

 Lys Asp Asn Glu Asn Lys Gln Lys Val Ile Val Cys Leu Glu Glu
                1940                1945                1950

 Glu Leu Ser Val Val Thr Ser Glu Arg Asn Gln Leu Arg Gly Glu
                1955                1960                1965

 Leu Asp Thr Met Ser Lys Lys Thr Thr Ala Leu Asp Gln Leu Ser
                1970                1975                1980

 Glu Lys Met Lys Glu Lys Thr Gln Glu Leu Glu Ser His Gln Ser
                1985                1990                1995

 Glu Cys Leu His Cys
                2000

<210> 1683
<211> 3213
<212> DNA
<213> Homo sapien

<400> 1683
 gaccgaagca agagctggtt caggtggcag ccacagcagc ctcagggacc 50

 tcagcaacta tggcctcctg cccagactct gataatagct gggtgcttgc 100

 tggctccgag agcctgccag tggagacact gggcccggca tccaggatgg 150

 acccagaatc tgagagagcc ctgcaggccc ctcacagccc ctccaagaca 200

 gatgggaaag aattagctgg gaccatggat ggagaaggga cgctcttcca 250

 gactgaaagc cctcagtctg gcagcattct aacagaggag actgaggtca 300

 agggcaccct ggaaggtgat gtttgtggtg tggagcctcc tggcccagga 350

 gacacagtag tccagggaga cctgcaggag accaccgtgg tgacaggcct 400

 gggaccagac acacaggacc tggaaggcca gagccctcca cagagcctgc 450

 cttcaacccc caaagcagct tggatcaggg aggagggccg ctgctccagc 500

 agtgacgatg acaccgacgt ggacatggag ggtctgcgga gacggcgggg 550

 ccgggaggcc ggcccacctc agcccatggt gcccctggct gtggagaacc 600

 aggctggggg tgagggtgca ggcggggagc tgggcatctc cctcaacatg 650

 tgcctccttg gggccctggt tctgcttggc ctgggggtcc tcctcttctc 700

 aggtggcctc tcagagtctg agactgggcc catggaggaa gtggagcggc 750

 aggtcctccc agaccccgag gtgctggaag ctgtggggga caggcaggat 800

 gggctaaggg aacagctgca ggccccagtg cctcctgaca gtgtccccag 850

 cctgcaaaac atgggtcttc tgctggacaa gctggccaag gagaaccagg 900

 acatccggct gctgcaggcc cagctgcagg cccaaaagga agagcttcag 950

 agcctgatgc accagcccaa agggctagag gaggagaatg cccagctccg 1000

 gggggctctg cagcagggcg aagccttcca gcgggctctg gagtcagagc 1050

 tgcagcagct gcgggcccgg ctccaggggc tggaggccga ctgtgtccgg 1100

 ggcccagatg gggtgtgcct cagtgggggt agaggcccac agggtgacaa 1150

 ggccatcagg gagcaaggcc ccagggagca ggagccagaa ctcagcttcc 1200

 tgaagcagaa ggaacagctg gaggctgagg cacaggcatt aaggcaagag 1250

 ttagagaggc agcgacggct gctggggtct gtacagcagg atctggagag 1300

 gagcttgcag gatgccagcc gcggggaccc agctcatgct ggcttggctg 1350

 agctgggcca cagattggcc cagaaactgc agggcctgga gaactggggc 1400

 caggaccctg gggtctctgc caatgcctca aaggcctggc accagaagtc 1450

 ccacttccag aattctaggg agtggagtgg aaaggaaaag tggtgggatg 1500

 ggcagagaga ccggaaggct gagcactgga aacataagaa ggaagaatct 1550

 ggccgggaaa ggaagaagaa ctggggaggt caggaggaca gggagccagc 1600

 aggaaggtgg aaggagggca ggccaagggt ggaggagtcg gggagcaaga 1650

 aggagggcaa gcgacagggc ccgaaggaac ccccaaggaa aagtggtagc 1700

 ttccactcct ctggagaaaa gcagaagcaa cctcggtgga gggaagggac 1750

 taaggacagc catgaccccc tgccatcctg ggcagagctg ttgaggccca 1800

 agtaccgggc accccagggc tgctcaggtg tggacgagtg tgcccggcag 1850

 gagggcctga ctttctttgg cacagagcta gccccagtgc ggcaacagga 1900

 gctggcctct ctgctaagaa catacttggc acggctgccc tgggctgggc 1950

 agctgaccaa ggagctaccc ctctcacctg ctttctttgg tgaggatggc 2000

 atcttccgtc atgaccgcct ccgcttccgg gattttgtgg atgccctgga 2050

 ggacagcttg gaggaggtgg ctgtgcaaca gacaggtgat gatgatgaag 2100

 tagatgactt tgaggacttc atcttcagcc acttctttgg agacaaagca 2150

 ctgaagaaga ggtcagggaa gaaggacaag cactcacaga gcccaagagc 2200

 tgcggggccc agggaggggc acagccatag ccaccaccac caccaccggg 2250

 gctgacaccc tgccccacag ggaatggcct tggcctggcc cagcccaaga 2300

 tcccagcgtt atctaactcc tggagggtgg actctgtcct ggcttgtttg 2350

 gtgtcctcag atatctttca cacagtagag caaaatcacc agccctgcac 2400

 tgatgtcact ttatgtagaa aaaggcctta gctggacctg cgttgccgtc 2450

 tatgcaaatg catgcaaata ctccaggccc tgggatgtgg gcttgtgttt 2500

 tgtcactgtg aagggggaga tgggagagga gcctgttttg gggtggggtc 2550

 tggggaaggc aatctgattc tgaagctaaa gagctttcat cctcttgagt 2600

 gtatgtcccc atagtgggcc ccttgaccca catgctgacc ggtgccttgg 2650

 gatttgacta gagttgctgg ctcgaggccc agcacgagga cttaccctgg 2700

 ggttttgtta ggtttggaag cagctgtccc tagggggtga agtccccccc 2750

 cttttttttt ttacccctgc ttctcccacg gcttcacctc cctatgtgaa 2800

 ctgtagactc agatcccaat aaagtgctgt tgcagctatg atgctaggtg 2850

 gtttctaagc acaggggaca ccccacaccc cctgcctgaa tggatgggtc 2900

 catcccaggc actggtactt gcccccttgt tctgtatccc cctttgccct 2950

 tgccttgccc ttccaacaaa ccctaggccc ttgagaagct gatacttctc 3000

 cttttgctca cagctgcctt ggccccaccc ctgggagatg tagcaaattg 3050

 agtgtgggtt ttggagtctg agcctcaggc tcaaatccag gccaagtgat 3100

 cttgggcaag ttaatctctg ggaactttgg gtttcttatc ctcaaaaaag 3150

 gcgatggaag ggctggggaa gtgattaaat aaaagcaacg caagaaaaaa 3200

 aaaaaaaaaa aaa 3213

<210> 1684
<211> 731
<212> PRT
<213> Homo sapien

<400> 1684
 Met Ala Ser Cys Pro Asp Ser Asp Asn Ser Trp Val Leu Ala Gly
   1               5                  10                  15

 Ser Glu Ser Leu Pro Val Glu Thr Leu Gly Pro Ala Ser Arg Met
                  20                  25                  30

 Asp Pro Glu Ser Glu Arg Ala Leu Gln Ala Pro His Ser Pro Ser
                  35                  40                  45

 Lys Thr Asp Gly Lys Glu Leu Ala Gly Thr Met Asp Gly Glu Gly
                  50                  55                  60

 Thr Leu Phe Gln Thr Glu Ser Pro Gln Ser Gly Ser Ile Leu Thr
                  65                  70                  75

 Glu Glu Thr Glu Val Lys Gly Thr Leu Glu Gly Asp Val Cys Gly
                  80                  85                  90

 Val Glu Pro Pro Gly Pro Gly Asp Thr Val Val Gln Gly Asp Leu
                  95                 100                 105

 Gln Glu Thr Thr Val Val Thr Gly Leu Gly Pro Asp Thr Gln Asp
                 110                 115                 120

 Leu Glu Gly Gln Ser Pro Pro Gln Ser Leu Pro Ser Thr Pro Lys
                 125                 130                 135

 Ala Ala Trp Ile Arg Glu Glu Gly Arg Cys Ser Ser Ser Asp Asp
                 140                 145                 150

 Asp Thr Asp Val Asp Met Glu Gly Leu Arg Arg Arg Arg Gly Arg
                 155                 160                 165

 Glu Ala Gly Pro Pro Gln Pro Met Val Pro Leu Ala Val Glu Asn
                 170                 175                 180

 Gln Ala Gly Gly Glu Gly Ala Gly Gly Glu Leu Gly Ile Ser Leu
                 185                 190                 195

 Asn Met Cys Leu Leu Gly Ala Leu Val Leu Leu Gly Leu Gly Val
                 200                 205                 210

 Leu Leu Phe Ser Gly Gly Leu Ser Glu Ser Glu Thr Gly Pro Met
                 215                 220                 225

 Glu Glu Val Glu Arg Gln Val Leu Pro Asp Pro Glu Val Leu Glu
                 230                 235                 240

 Ala Val Gly Asp Arg Gln Asp Gly Leu Arg Glu Gln Leu Gln Ala
                 245                 250                 255

 Pro Val Pro Pro Asp Ser Val Pro Ser Leu Gln Asn Met Gly Leu
                 260                 265                 270

 Leu Leu Asp Lys Leu Ala Lys Glu Asn Gln Asp Ile Arg Leu Leu
                 275                 280                 285

 Gln Ala Gln Leu Gln Ala Gln Lys Glu Glu Leu Gln Ser Leu Met
                 290                 295                 300

 His Gln Pro Lys Gly Leu Glu Glu Glu Asn Ala Gln Leu Arg Gly
                 305                 310                 315

 Ala Leu Gln Gln Gly Glu Ala Phe Gln Arg Ala Leu Glu Ser Glu
                 320                 325                 330

 Leu Gln Gln Leu Arg Ala Arg Leu Gln Gly Leu Glu Ala Asp Cys
                 335                 340                 345

 Val Arg Gly Pro Asp Gly Val Cys Leu Ser Gly Gly Arg Gly Pro
                 350                 355                 360

 Gln Gly Asp Lys Ala Ile Arg Glu Gln Gly Pro Arg Glu Gln Glu
                 365                 370                 375

 Pro Glu Leu Ser Phe Leu Lys Gln Lys Glu Gln Leu Glu Ala Glu
                 380                 385                 390

 Ala Gln Ala Leu Arg Gln Glu Leu Glu Arg Gln Arg Arg Leu Leu
                 395                 400                 405

 Gly Ser Val Gln Gln Asp Leu Glu Arg Ser Leu Gln Asp Ala Ser
                 410                 415                 420

 Arg Gly Asp Pro Ala His Ala Gly Leu Ala Glu Leu Gly His Arg
                 425                 430                 435

 Leu Ala Gln Lys Leu Gln Gly Leu Glu Asn Trp Gly Gln Asp Pro
                 440                 445                 450

 Gly Val Ser Ala Asn Ala Ser Lys Ala Trp His Gln Lys Ser His
                 455                 460                 465

 Phe Gln Asn Ser Arg Glu Trp Ser Gly Lys Glu Lys Trp Trp Asp
                 470                 475                 480

 Gly Gln Arg Asp Arg Lys Ala Glu His Trp Lys His Lys Lys Glu
                 485                 490                 495

 Glu Ser Gly Arg Glu Arg Lys Lys Asn Trp Gly Gly Gln Glu Asp
                 500                 505                 510

 Arg Glu Pro Ala Gly Arg Trp Lys Glu Gly Arg Pro Arg Val Glu
                 515                 520                 525

 Glu Ser Gly Ser Lys Lys Glu Gly Lys Arg Gln Gly Pro Lys Glu
                 530                 535                 540

 Pro Pro Arg Lys Ser Gly Ser Phe His Ser Ser Gly Glu Lys Gln
                 545                 550                 555

 Lys Gln Pro Arg Trp Arg Glu Gly Thr Lys Asp Ser His Asp Pro
                 560                 565                 570

 Leu Pro Ser Trp Ala Glu Leu Leu Arg Pro Lys Tyr Arg Ala Pro
                 575                 580                 585

 Gln Gly Cys Ser Gly Val Asp Glu Cys Ala Arg Gln Glu Gly Leu
                 590                 595                 600

 Thr Phe Phe Gly Thr Glu Leu Ala Pro Val Arg Gln Gln Glu Leu
                 605                 610                 615

 Ala Ser Leu Leu Arg Thr Tyr Leu Ala Arg Leu Pro Trp Ala Gly
                 620                 625                 630

 Gln Leu Thr Lys Glu Leu Pro Leu Ser Pro Ala Phe Phe Gly Glu
                 635                 640                 645

 Asp Gly Ile Phe Arg His Asp Arg Leu Arg Phe Arg Asp Phe Val
                 650                 655                 660

 Asp Ala Leu Glu Asp Ser Leu Glu Glu Val Ala Val Gln Gln Thr
                 665                 670                 675

 Gly Asp Asp Asp Glu Val Asp Asp Phe Glu Asp Phe Ile Phe Ser
                 680                 685                 690

 His Phe Phe Gly Asp Lys Ala Leu Lys Lys Arg Ser Gly Lys Lys
                 695                 700                 705

 Asp Lys His Ser Gln Ser Pro Arg Ala Ala Gly Pro Arg Glu Gly
                 710                 715                 720

 His Ser His Ser His His His His His Arg Gly
                 725                 730

<210> 1685
<211> 1425
<212> DNA
<213> Homo sapien

<400> 1685
 cagtctgaga acaagaaaga agaacttctg tctcgagggt ctcactgtca 50

 accaggccag agtgcagtga agatcatacc tcactacatc cgtgaactcc 100

 cgggctcctc ccacctaagt ctcttgagta gctgggactt caggagactg 150

 aagccaagga taccagcaga gccaacattt gcttcaagtt cctgggcctg 200

 ctgacagcgt gcaggatgct gttggaaccc ggcagaggct gctgtgccct 250

 ggccatcctg ctggcaattg tggacatcca gtctggtgga tgcattaaca 300

 tcaccagctc agcttcccag gaaggaacgc gactaaactt aatctgtact 350

 gtatggcata agaaagaaga ggctgagggg tttgtagtgt ttttgtgcaa 400

 ggacaggtct ggagactgtt ctcctgagac cagtttaaaa cagctgagac 450

 ttaaaaggga tcctgggata gatggtgttg gtgaaatatc atctcagttg 500

 atgttcacca taagccaagt cacaccgttg cacagtggga cctaccagtg 550

 ttgtgccaga agccagaagt caggtatccg ccttcagggc cattttttct 600

 ccattctatt cacagagaca gggaactaca cagtgacggg attgaaacaa 650

 agacaacacc ttgagttcag ccataatgaa ggcactctca gttcaggctt 700

 cctacaagaa aaggtctggg taatgctggt caccagcctt gtggcccttc 750

 aagctttgta agcctgtcca aaagaacttt taaaacagct acagcaagat 800

 gagtctgact atggcttagt atctttctca ttacaatagg cacagagaag 850

 aatgcaacag ggcacagggg aagagatgct aaatatacca agaatctgtg 900

 gaaatataag ctggggcaaa tcagtgtaat ccttgacttt gctcctcacc 950

 atcagggcaa acttgccttc ttccctccta agctccagta aataaacaga 1000

 acagctttca ccaaagtggg tagtatagtc ctcaaatatc ggataaatat 1050

 atgcgttttt gtaccccaga aaaacttttc ctccctcttc atcaacatag 1100

 taaaataagt caaacaaaat gagaacacca aattttgggg gaataaattt 1150

 ttatttaaca ctgcaaagga aagagagaga aaacaagcaa agataggtag 1200

 gacagaaagg aagacagcca gatccagtga ttgacttggc atgaaaatga 1250

 gaaaatgcag acagacctca acattcaaca ttcaacaaca tccatacagc 1300

 actgctggag gaagaggaag atttgtgcag accaagagca ccacagacta 1350

 caactgccca gcttcatcta aatacttgtt aacctctttg gtcatttctc 1400

 tttttaaata aatgcccata gcagt 1425

<210> 1686
<211> 181
<212> PRT
<213> Homo sapien

<400> 1686
 Met Leu Leu Glu Pro Gly Arg Gly Cys Cys Ala Leu Ala Ile Leu
   1               5                  10                  15

 Leu Ala Ile Val Asp Ile Gln Ser Gly Gly Cys Ile Asn Ile Thr
                  20                  25                  30

 Ser Ser Ala Ser Gln Glu Gly Thr Arg Leu Asn Leu Ile Cys Thr
                  35                  40                  45

 Val Trp His Lys Lys Glu Glu Ala Glu Gly Phe Val Val Phe Leu
                  50                  55                  60

 Cys Lys Asp Arg Ser Gly Asp Cys Ser Pro Glu Thr Ser Leu Lys
                  65                  70                  75

 Gln Leu Arg Leu Lys Arg Asp Pro Gly Ile Asp Gly Val Gly Glu
                  80                  85                  90

 Ile Ser Ser Gln Leu Met Phe Thr Ile Ser Gln Val Thr Pro Leu
                  95                 100                 105

 His Ser Gly Thr Tyr Gln Cys Cys Ala Arg Ser Gln Lys Ser Gly
                 110                 115                 120

 Ile Arg Leu Gln Gly His Phe Phe Ser Ile Leu Phe Thr Glu Thr
                 125                 130                 135

 Gly Asn Tyr Thr Val Thr Gly Leu Lys Gln Arg Gln His Leu Glu
                 140                 145                 150

 Phe Ser His Asn Glu Gly Thr Leu Ser Ser Gly Phe Leu Gln Glu
                 155                 160                 165

 Lys Val Trp Val Met Leu Val Thr Ser Leu Val Ala Leu Gln Ala
                 170                 175                 180

 Leu


<210> 1687
<211> 1282
<212> DNA
<213> Homo sapien

<400> 1687
 aagccaccca gcctatgcat ccgctcctca atcctctcct gttggcactg 50

 ggcctcatgg cgcttttgtt gaccacggtc attgctctca cttgccttgg 100

 cggctttgcc tccccaggcc ctgtgcctcc ctctacagcc ctcagggagc 150

 tcattgagga gctggtcaac atcacccaga accagaaggc tccgctctgc 200

 aatggcagca tggtatggag catcaacctg acagctggca tgtactgtgc 250

 agccctggaa tccctgatca acgtgtcagg ctgcagtgcc atcgagaaga 300

 cccagaggat gctgagcgga ttctgcccgc acaaggtctc agctgggcag 350

 ttttccagct tgcatgtccg agacaccaaa atcgaggtgg cccagtttgt 400

 aaaggacctg ctcttacatt taaagaaact ttttcgcgag ggacagttca 450

 actgaaactt cgaaagcatc attatttgca gagacaggac ctgactattg 500

 aagttgcaga ttcatttttc tttctgatgt caaaaatgtc ttgggtaggc 550

 gggaaggagg gttagggagg ggtaaaattc cttagcttag acctcagcct 600

 gtgctgcccg tcttcagcct agccgacctc agccttcccc ttgcccaggg 650

 ctcagcctgg tgggcctcct ctgtccaggg ccctgagctc ggtggaccca 700

 gggatgacat gtccctacac ccctcccctg ccctagagca cactgtagca 750

 ttacagtggg tgcccccctt gccagacatg tggtgggaca gggacccact 800

 tcacacacag gcaactgagg cagacagcag ctcaggcaca cttcttcttg 850

 gtcttattta ttattgtgtg ttatttaaat gagtgtgttt gtcaccgttg 900

 gggattgggg aagactgtgg ctgctagcac ttggagccaa gggttcagag 950

 actcagggcc ccagcactaa agcagtggac accaggagtc cctggtaata 1000

 agtactgtgt acagaattct gctacctcac tggggtcctg gggcctcgga 1050

 gcctcatccg aggcagggtc aggagagggg cagaacagcc gctcctgtct 1100

 gccagccagc agccagctct cagccaacga gtaatttatt gtttttcctt 1150

 gtatttaaat attaaatatg ttagcaaaga gttaatatat agaagggtac 1200

 cttgaacact gggggagggg acattgaaca agttgtttca ttgactatca 1250

 aactgaagcc agaaataaag ttggtgacag at 1282

<210> 1688
<211> 146
<212> PRT
<213> Homo sapien

<400> 1688
 Met His Pro Leu Leu Asn Pro Leu Leu Leu Ala Leu Gly Leu Met
   1               5                  10                  15

 Ala Leu Leu Leu Thr Thr Val Ile Ala Leu Thr Cys Leu Gly Gly
                  20                  25                  30

 Phe Ala Ser Pro Gly Pro Val Pro Pro Ser Thr Ala Leu Arg Glu
                  35                  40                  45

 Leu Ile Glu Glu Leu Val Asn Ile Thr Gln Asn Gln Lys Ala Pro
                  50                  55                  60

 Leu Cys Asn Gly Ser Met Val Trp Ser Ile Asn Leu Thr Ala Gly
                  65                  70                  75

 Met Tyr Cys Ala Ala Leu Glu Ser Leu Ile Asn Val Ser Gly Cys
                  80                  85                  90

 Ser Ala Ile Glu Lys Thr Gln Arg Met Leu Ser Gly Phe Cys Pro
                  95                 100                 105

 His Lys Val Ser Ala Gly Gln Phe Ser Ser Leu His Val Arg Asp
                 110                 115                 120

 Thr Lys Ile Glu Val Ala Gln Phe Val Lys Asp Leu Leu Leu His
                 125                 130                 135

 Leu Lys Lys Leu Phe Arg Glu Gly Gln Phe Asn
                 140                 145

<210> 1689
<211> 825
<212> DNA
<213> Homo sapien

<400> 1689
 atcactctct ttaatcacta ctcacattaa cctcaactcc tgccacaatg 50

 tacaggatgc aactcctgtc ttgcattgca ctaattcttg cacttgtcac 100

 aaacagtgca cctacttcaa gttcgacaaa gaaaacaaag aaaacacagc 150

 tacaactgga gcatttactg ctggatttac agatgatttt gaatggaatt 200

 aataattaca agaatcccaa actcaccagg atgctcacat ttaagtttta 250

 catgcccaag aaggccacag aactgaaaca gcttcagtgt ctagaagaag 300

 aactcaaacc tctggaggaa gtgctgaatt tagctcaaag caaaaacttt 350

 cacttaagac ccagggactt aatcagcaat atcaacgtaa tagttctgga 400

 actaaaggga tctgaaacaa cattcatgtg tgaatatgca gatgagacag 450

 caaccattgt agaatttctg aacagatgga ttaccttttg tcaaagcatc 500

 atctcaacac taacttgata attaagtgct tcccacttaa aacatatcag 550

 gccttctatt tatttattta aatatttaaa ttttatattt attgttgaat 600

 gtatggttgc tacctattgt aactattatt cttaatctta aaactataaa 650

 tatggatctt ttatgattct ttttgtaagc cctaggggct ctaaaatggt 700

 ttaccttatt tatcccaaaa atatttatta ttatgttgaa tgttaaatat 750

 agtatctatg tagattggtt agtaaaacta tttaataaat ttgataaata 800

 taaaaaaaaa aaacaaaaaa aaaaa 825

<210> 1690
<211> 156
<212> PRT
<213> Homo sapien

<400> 1690
 Met Tyr Arg Met Gln Leu Leu Ser Cys Ile Ala Leu Ile Leu Ala
   1               5                  10                  15

 Leu Val Thr Asn Ser Ala Pro Thr Ser Ser Ser Thr Lys Lys Thr
                  20                  25                  30

 Lys Lys Thr Gln Leu Gln Leu Glu His Leu Leu Leu Asp Leu Gln
                  35                  40                  45

 Met Ile Leu Asn Gly Ile Asn Asn Tyr Lys Asn Pro Lys Leu Thr
                  50                  55                  60

 Arg Met Leu Thr Phe Lys Phe Tyr Met Pro Lys Lys Ala Thr Glu
                  65                  70                  75

 Leu Lys Gln Leu Gln Cys Leu Glu Glu Glu Leu Lys Pro Leu Glu
                  80                  85                  90

 Glu Val Leu Asn Leu Ala Gln Ser Lys Asn Phe His Leu Arg Pro
                  95                 100                 105

 Arg Asp Leu Ile Ser Asn Ile Asn Val Ile Val Leu Glu Leu Lys
                 110                 115                 120

 Gly Ser Glu Thr Thr Phe Met Cys Glu Tyr Ala Asp Glu Thr Ala
                 125                 130                 135

 Thr Ile Val Glu Phe Leu Asn Arg Trp Ile Thr Phe Cys Gln Ser
                 140                 145                 150

 Ile Ile Ser Thr Leu Thr
                 155

<210> 1691
<211> 2918
<212> DNA
<213> Homo sapien

<400> 1691
 caggacagag catggatcgc ctacagactg cactcctggt tgtcctcgtc 50

 ctccttgctg tggcgcttca agcaactgag gcaggcccct acggcgccaa 100

 catggaagac agcgtctgct gccgtgatta cgtccgttac cgtctgcccc 150

 tgcgcgtggt gaaacacttc tactggacct cagactcctg cccgaggcct 200

 ggcgtggtgt tgctaacctt cagggataag gagatctgtg ccgatcccag 250

 agtgccctgg gtgaagatga ttctcaataa gctgagccaa tgaagagcct 300

 actctgatga ccgtggcctt ggctcctcca ggaaggctca ggagccctac 350

 ctccctgcca ttatagctgc tccccgccag aagcctgtgc caactctctg 400

 cattccctga tctccatccc tgtggctgtc acccttggtc acctccgtgc 450

 tgtcactgcc atctcccccc tgacccctct aacccatcct ctgcctccct 500

 ccctgcagtc agagggtcct gttcccatca gcgattcccc tgcttaaacc 550

 cttccatgac tccccactgc cctaagctga ggtcagtctc ccaagcctgg 600

 catgtggccc tctggatctg ggttccatct ctgtctccag cctgcccact 650

 tcccttcatg aatgttgggt tctagctccc tgttctccaa acccatacta 700

 cacatcccac ttctgggtct ttgcctggga tgttgctgac acccagaaag 750

 tcccaccacc tgcacatgtg tagccccacc agccctccaa ggcattgctc 800

 gcccaagcag ctggtaattc catttcatgt attagatgtc ccctggccct 850

 ctgtcccctc ttaataaccc tagtcacagt ctccgcagat tcttgggatt 900

 tgggggtttt ctcccccacc tctccactag ttggaccaag gtttctagct 950

 aagttactct agtctccaag cctctagcat agagcactgc agacaggccc 1000

 tggctcagaa tcagagccca gaaagtggct gcagacaaaa tcaataaaac 1050

 taatgtccct cccctctccc tgccaaaagg cagttacata tcaatacaga 1100

 gactcaaggt cactagaaat gggccagctg ggtcaatgtg aagccccaaa 1150

 tttgcccaga ttcacctttc ttcccccact cccttttttt tttttttttt 1200

 gagatggagt ttcgctcttg tcacccacgc tggagtgcaa tggtgtggtc 1250

 ttggcttatt gaagcctctg cctcctgggt tcaagtgatt ctcttgcctc 1300

 agcctcctga gtagctggga ttacaggttc ctgctaccac gcccagctaa 1350

 tttttgtatt tttagtagag acgaggcttc accatgttgg ccaggctggt 1400

 ctcgaactcc tgtcctcagg taatccgccc acctcagcct cccaaagtgc 1450

 tgggattaca ggcgtgagcc acagtgcctg gcctcttccc tctccccacc 1500

 ccccccccaa cttttttttt tttttatggc agggtctcac tctgtcgccc 1550

 aggctggagt gcagtggcgt gatctcggct cactacaacc tcgacctcct 1600

 gggttcaagc gattctccca ccccagcctc ccaagtagct gggattacag 1650

 gtgtgtgcca ctacggctgg ctaatttttg tatttttagt agagacaggt 1700

 ttcaccatat tggccaggct ggtcttgaac tcctgacctc aagtgatcca 1750

 ccttccttgt gctcccaaag tgctgagatt acaggcgtga gctatcacac 1800

 ccagcctccc cctttttttc ctaataggag actcctgtac ctttcttcgt 1850

 tttacctatg tgtcgtgtct gcttacattt ccttctcccc tcaggctttt 1900

 tttgggtggt cctccaacct ccaataccca ggcctggcct cttcagagta 1950

 ccccccattc cactttccct gcctccttcc ttaaatagct gacaatcaaa 2000

 ttcatgctat ggtgtgaaag actacctttg acttggtatt ataagctgga 2050

 gttatatatg tatttgaaaa cagagtaaat acttaagagg ccaaatagat 2100

 gaatggaaga attttaggaa ctgtgagagg gggacaaggt ggagctttcc 2150

 tggccctggg aggaagctgg ctgtggtagc gtagcgctct ctctctctgt 2200

 ctgtggcagg aggcaaagag tagggtgtaa ttgagtgaag gaatcctggg 2250

 tagagaccat tctcaggtgg ttgggccagg ctaaagactg ggatttgggt 2300

 ctatctatgc ctttctggct gatttttgta gagacggggt tttgccatgt 2350

 tacccaggct ggtctcaaac tcctgggctc aagcgatcct cctggctcag 2400

 cctcccaaag tgctgggatt acaggcgtga gtcactgcgc ctggcttcct 2450

 cttcctcttg agaaatattc ttttcataca gcaagtatgg gacagcagtg 2500

 tcccaggtaa aggacataaa tgttacaagt gtctggtcct ttctgaggga 2550

 ggctggtgcc gctctgcagg gtatttgaac ctgtggaatt ggaggaggcc 2600

 atttcactcc ctgaacccag cctgacaaat cacagtgaga atgttcacct 2650

 tataggcttg ctgtggggct caggttgaaa gtgtggggag tgacactgcc 2700

 taggcatcca gctcagtgtc atccagggcc tgtgtccctc ccgaacccag 2750

 ggtcaacctg cctaccacag gcactagaag gacgaatctg cctactgccc 2800

 atgaacgggg ccctcaagcg tcctgggatc tccttctccc tcctgtcctg 2850

 tccttgcccc tcaggactgc tggaaaataa atcctttaaa atagaaaaaa 2900

 aaaaaaaaaa aaaaaaaa 2918

<210> 1692
<211> 93
<212> PRT
<213> Homo sapien

<400> 1692
 Met Asp Arg Leu Gln Thr Ala Leu Leu Val Val Leu Val Leu Leu
   1               5                  10                  15

 Ala Val Ala Leu Gln Ala Thr Glu Ala Gly Pro Tyr Gly Ala Asn
                  20                  25                  30

 Met Glu Asp Ser Val Cys Cys Arg Asp Tyr Val Arg Tyr Arg Leu
                  35                  40                  45

 Pro Leu Arg Val Val Lys His Phe Tyr Trp Thr Ser Asp Ser Cys
                  50                  55                  60

 Pro Arg Pro Gly Val Val Leu Leu Thr Phe Arg Asp Lys Glu Ile
                  65                  70                  75

 Cys Ala Asp Pro Arg Val Pro Trp Val Lys Met Ile Leu Asn Lys
                  80                  85                  90

 Leu Ser Gln


<210> 1693
<211> 1816
<212> DNA
<213> Homo sapien

<400> 1693
 cttctctgcc agaagatacc atttcaactt taacacagca tgatcgaaac 50

 atacaaccaa acttctcccc gatctgcggc cactggactg cccatcagca 100

 tgaaaatttt tatgtattta cttactgttt ttcttatcac ccagatgatt 150

 gggtcagcac tttttgctgt gtatcttcat agaaggttgg acaagataga 200

 agatgaaagg aatcttcatg aagattttgt attcatgaaa acgatacaga 250

 gatgcaacac aggagaaaga tccttatcct tactgaactg tgaggagatt 300

 aaaagccagt ttgaaggctt tgtgaaggat ataatgttaa acaaagagga 350

 gacgaagaaa gaaaacagct ttgaaatgca aaaaggtgat cagaatcctc 400

 aaattgcggc acatgtcata agtgaggcca gcagtaaaac aacatctgtg 450

 ttacagtggg ctgaaaaagg atactacacc atgagcaaca acttggtaac 500

 cctggaaaat gggaaacagc tgaccgttaa aagacaagga ctctattata 550

 tctatgccca agtcaccttc tgttccaatc gggaagcttc gagtcaagct 600

 ccatttatag ccagcctctg cctaaagtcc cccggtagat tcgagagaat 650

 cttactcaga gctgcaaata cccacagttc cgccaaacct tgcgggcaac 700

 aatccattca cttgggagga gtatttgaat tgcaaccagg tgcttcggtg 750

 tttgtcaatg tgactgatcc aagccaagtg agccatggca ctggcttcac 800

 gtcctttggc ttactcaaac tctgaacagt gtcaccttgc aggctgtggt 850

 ggagctgacg ctgggagtct tcataataca gcacagcggt taagcccacc 900

 ccctgttaac tgcctattta taaccctagg atcctcctta tggagaacta 950

 tttattatac actccaaggc atgtagaact gtaataagtg aattacaggt 1000

 cacatgaaac caaaacgggc cctgctccat aagagcttat atatctgaag 1050

 cagcaacccc actgatgcag acatccagag agtcctatga aaagacaagg 1100

 ccattatgca caggttgaat tctgagtaaa cagcagataa cttgccaagt 1150

 tcagttttgt ttctttgcgt gcagtgtctt tccatggata atgcatttga 1200

 tttatcagtg aagatgcaga agggaaatgg ggagcctcag ctcacattca 1250

 gttatggttg actctgggtt cctatggcct tgttggaggg ggccaggctc 1300

 tagaacgtct aacacagtgg agaaccgaaa cccccccccc cccccccgcc 1350

 accctctcgg acagttattc attctctttc aatctctctc tctccatctc 1400

 tctctttcag tctctctctc tcaacctctt tcttccaatc tctctttctc 1450

 aatctctctg tttccctttg tcagtctctt ccctccccca gtctctcttc 1500

 tcaatccccc tttctaacac acacacacac acacacacac acacacacac 1550

 acacacacac acacacacac acacacacac agagtcaggc cgttgctagt 1600

 cagttctctt ctttccaccc tgtccctatc tctaccacta tagatgaggg 1650

 tgaggagtag ggagtgcagc cctgagcctg cccactcctc attacgaaat 1700

 gactgtattt aaaggaaatc tattgtatct acctgcagtc tccattgttt 1750

 ccagagtgaa cttgtaatta tcttgttatt tattttttga ataataaaga 1800

 cctcttaaca ttaaaa 1816

<210> 1694
<211> 261
<212> PRT
<213> Homo sapien

<400> 1694
 Met Ile Glu Thr Tyr Asn Gln Thr Ser Pro Arg Ser Ala Ala Thr
   1               5                  10                  15

 Gly Leu Pro Ile Ser Met Lys Ile Phe Met Tyr Leu Leu Thr Val
                  20                  25                  30

 Phe Leu Ile Thr Gln Met Ile Gly Ser Ala Leu Phe Ala Val Tyr
                  35                  40                  45

 Leu His Arg Arg Leu Asp Lys Ile Glu Asp Glu Arg Asn Leu His
                  50                  55                  60

 Glu Asp Phe Val Phe Met Lys Thr Ile Gln Arg Cys Asn Thr Gly
                  65                  70                  75

 Glu Arg Ser Leu Ser Leu Leu Asn Cys Glu Glu Ile Lys Ser Gln
                  80                  85                  90

 Phe Glu Gly Phe Val Lys Asp Ile Met Leu Asn Lys Glu Glu Thr
                  95                 100                 105

 Lys Lys Glu Asn Ser Phe Glu Met Gln Lys Gly Asp Gln Asn Pro
                 110                 115                 120

 Gln Ile Ala Ala His Val Ile Ser Glu Ala Ser Ser Lys Thr Thr
                 125                 130                 135

 Ser Val Leu Gln Trp Ala Glu Lys Gly Tyr Tyr Thr Met Ser Asn
                 140                 145                 150

 Asn Leu Val Thr Leu Glu Asn Gly Lys Gln Leu Thr Val Lys Arg
                 155                 160                 165

 Gln Gly Leu Tyr Tyr Ile Tyr Ala Gln Val Thr Phe Cys Ser Asn
                 170                 175                 180

 Arg Glu Ala Ser Ser Gln Ala Pro Phe Ile Ala Ser Leu Cys Leu
                 185                 190                 195

 Lys Ser Pro Gly Arg Phe Glu Arg Ile Leu Leu Arg Ala Ala Asn
                 200                 205                 210

 Thr His Ser Ser Ala Lys Pro Cys Gly Gln Gln Ser Ile His Leu
                 215                 220                 225

 Gly Gly Val Phe Glu Leu Gln Pro Gly Ala Ser Val Phe Val Asn
                 230                 235                 240

 Val Thr Asp Pro Ser Gln Val Ser His Gly Thr Gly Phe Thr Ser
                 245                 250                 255

 Phe Gly Leu Leu Lys Leu
                 260

<210> 1695
<211> 615
<212> DNA
<213> Homo sapien

<400> 1695
 gctcagagag aagtgacttt gagctcacag tgtcaccgcc tgctgatggg 50

 agagctgaat tcaaaaccag ggtgtctccc tgagcagagg gacctgcaca 100

 cagagactcc ctcctgggct cctggcacca tggccccact gaagatgctg 150

 gccctggtca ccctcctcct gggggcttct ctgcagcaca tccacgcagc 200

 tcgagggacc aatgtgggcc gggagtgctg cctggagtac ttcaagggag 250

 ccattcccct tagaaagctg aagacgtggt accagacatc tgaggactgc 300

 tccagggatg ccatcgtttt tgtaactgtg cagggcaggg ccatctgttc 350

 ggaccccaac aacaagagag tgaagaatgc agttaaatac ctgcaaagcc 400

 ttgagaggtc ttgaagcctc ctcaccccag actcctgact gtctcccggg 450

 actacctggg acctccaccg ttggtgttca ccgcccccac cctgagcgcc 500

 tgggtccagg ggaggccttc cagggacgaa gaagagccac agtgagggag 550

 atcccatccc cttgtctgaa ctggagccat gggcacaaag ggcccagatt 600

 aaagtcttta tcctc 615

<210> 1696
<211> 94
<212> PRT
<213> Homo sapien

<400> 1696
 Met Ala Pro Leu Lys Met Leu Ala Leu Val Thr Leu Leu Leu Gly
   1               5                  10                  15

 Ala Ser Leu Gln His Ile His Ala Ala Arg Gly Thr Asn Val Gly
                  20                  25                  30

 Arg Glu Cys Cys Leu Glu Tyr Phe Lys Gly Ala Ile Pro Leu Arg
                  35                  40                  45

 Lys Leu Lys Thr Trp Tyr Gln Thr Ser Glu Asp Cys Ser Arg Asp
                  50                  55                  60

 Ala Ile Val Phe Val Thr Val Gln Gly Arg Ala Ile Cys Ser Asp
                  65                  70                  75

 Pro Asn Asn Lys Arg Val Lys Asn Ala Val Lys Tyr Leu Gln Ser
                  80                  85                  90

 Leu Glu Arg Ser


<210> 1697
<211> 3642
<212> DNA
<213> Homo sapien

<400> 1697
 ctcagctctc ggagtaggaa gctcgggcgc tccggctgta aggagccgcg 50

 gcagggggaa aatggagccc ttcaccaatg atcggcttca gctccccagg 100

 aatatgattg aaaacagcat gtttgaggaa gaaccagatg tggtggattt 150

 agccaaagag ccttgtttac atcctctaga gcctgatgag gtggaatatg 200

 agccccgggg ttcccgactg ctggtgcggg gtcttggtga gcatgagatg 250

 gaggaggatg aagaggatta tgagtcatca gcaaagctgc tgggcatgtc 300

 cttcatgaat agaagctcag gccttcggaa cagtgcaact ggttacaggc 350

 agagcccaga tggggcttgt tcagtaccct ctgcaaggac catggtggtc 400

 tgtgcttttg tcatcgtggt tgctgtttct gtaatcatgg tgatttactt 450

 actgcccaga tgtaccttta ccaaagaagg ctgccataaa aaaaaccagt 500

 caattggact aattcagcca tttgcaacaa atgggaaatt gtttccatgg 550

 gcacagatca ggcttcccac tgccgttgtg ccactacgct atgaactcag 600

 cctacacccg aacctaacct cgatgacatt caggggttct gtgacaattt 650

 cagttcaggc tcttcaggtc acatggaata tcattcttca tagcacaggt 700

 cataatattt caagagtgac ctttatgtca gcagtttcaa gccaagaaaa 750

 acaagctgag atcctggaat atgcatatca tggacagatc gccattgttg 800

 cccccgaagc ccttctagca gggcacaatt atacgttgaa gatagagtac 850

 tcggcaaata tatctagttc ttattatggg ttttatggct tctcctacac 900

 agatgaaagt aatgagaaaa agtactttgc agcaactcag tttgaacccc 950

 tggcagcaag atctgctttt ccttgttttg atgaaccagc atttaaagcc 1000

 acttttatca tcaagatcat aagggatgag caatacaccg ctttatcaaa 1050

 tatgcctaag aagtcatcag tcgttctaga tgatggactt gttcaggatg 1100

 agttttctga gagtgtgaag atgagcactt acttggttgc tttcattgtg 1150

 ggagagatga agaacctgag tcaggacgta aatggaaccc tggtttctat 1200

 atatgctgta ccagaaaata ttggtcaagt tcattatgcc ttggaaacaa 1250

 ctgtgaagct tcttgagttt tttcaaaact actttgaaat tcagtaccca 1300

 cttaagaaat tggatttggt ggctattcct gactttgaag caggagcaat 1350

 ggaaaattgg ggtttgctca ccttccgaga ggagacactt ctgtatgaca 1400

 gtaacacttc ttcaatggcg gatagaaagc tggtgactaa aatcattgct 1450

 catgagctgg cccaccagtg gtttggcaat ctggtaacaa tgaagtggtg 1500

 gaatgaccta tggctaaatg aaggttttgc cactttcatg gagtatttct 1550

 ctttggaaaa aatattcaaa gagctttcta gttatgaaga tttcttagat 1600

 gctcgattta aaaccatgaa gaaagattcc ttaaattcat ctcatccaat 1650

 atcatcatct gttcagtctt cagaacaaat tgaagaaatg tttgattctc 1700

 tttcctattt taagggatct tctctcttgt tgatgttgaa aacttacctt 1750

 agtgaagatg tgtttcaaca tgctgttgtc ctttacctgc ataatcacag 1800

 ctatgcatct attcaaagtg atgatctgtg ggatagtttt aatgaggtca 1850

 caaaccaaac actagatgta aagagaatga tgaaaacctg gaccctgcag 1900

 aaaggatttc ctttagtgac tgttcaaaag aaaggaaagg aactttttat 1950

 acaacaagag agattctttt taaatatgaa gcctgaaatt cagccttcag 2000

 atacaagcta cctgtggcat attccactat cctatgtcac tgaaggaaga 2050

 aattattcaa aatatcaatc ggtatcatta ctggataaga aatcaggtgt 2100

 catcaatctt acagaagaag tgctgtgggt caaagtgaat ataaacatga 2150

 atggttatta tattgtacac tatgcagatg atgattggga agcactaatc 2200

 catcagttga aaataaatcc ttatgttctg agtgacaaag accgagccaa 2250

 ccttatcaac aacatctttg aacttgcagg cctaggcaag gtacctctca 2300

 agagggcctt tgatttgatt aattatcttg gaaatgagaa ccatactgca 2350

 cccatcaccg aagccctgtt tcagacagac ctcatctata acctccttga 2400

 aaaactggga tacatggatc tggcctcaag actggtgact agggtattta 2450

 aattacttca aaaccaaatt caacaacaaa cttggactga tgagggcact 2500

 ccatctatgc gagagcttcg gtcagccctg ctagagtttg cttgcaccca 2550

 caacctgggg aactgctcta ctactgccat gaaactgttt gatgactgga 2600

 tggcatccaa tggaactcaa agcctaccta ctgatgtcat gacaactgtg 2650

 ttcaaagttg gagcaaaaac tgacaaaggc tggtcattcc ttttgggcaa 2700

 atacatttct ataggctctg aagcagagaa gaacaaaata ctagaagcac 2750

 ttgccagctc agaggatgtg cggaagcttt actggttaat gaaaagtagc 2800

 ctgaatggag ataacttccg aacacagaag ctgtctttta tcattagaac 2850

 agtgggtcga cattttcctg gacacttact ggcatgggat tttgtcaaag 2900

 agaactggaa taagcttgta cagaagttcc ctctggggtc ctataccata 2950

 caaaatattg ttgctggatc aacttacctg ttttcaacaa agacacattt 3000

 atctgaggtt caggcattct ttgaaaatca gtcagaggca accttccggc 3050

 ttcgttgtgt ccaggaggct ttggaagtca ttcagttgaa tatccagtgg 3100

 atggagaaga acctcaaaag tctcacatgg tggctgtagc atgcacaacc 3150

 gcacctcatt ttgttgccca ttcagagagc ttgtaagctt gggctctgcc 3200

 gcttttgcaa aagccaaggt aaagccagga tcgctgccaa gttgtttgca 3250

 ctctttggag ttctagttag ctcagggcct gactgtattt ttcatccatc 3300

 ttttctgaag tgtctttggg cagtatgtag ttatttatta caaaattata 3350

 ttcacgtaaa tgccaaccat ctacaaaaac aatgagtaat ttttctactt 3400

 tgaagataca cagatgggga caaaaaccct gttttggaat tctgttctat 3450

 tcctcagtat ccagaaagtt actgacacag taaaacaagg aaagttctac 3500

 cctaagagcc gccatcactt caggccgctg gtttgtcagc catctgctgc 3550

 ttcttattga tagatggcat tggaatgtgg tacaaagtta gctctgaaga 3600

 atatggtaac gaagacaata aagcatgcac tgtaagaact ga 3642

<210> 1698
<211> 1025
<212> PRT
<213> Homo sapien

<400> 1698
 Met Glu Pro Phe Thr Asn Asp Arg Leu Gln Leu Pro Arg Asn Met
   1               5                  10                  15

 Ile Glu Asn Ser Met Phe Glu Glu Glu Pro Asp Val Val Asp Leu
                  20                  25                  30

 Ala Lys Glu Pro Cys Leu His Pro Leu Glu Pro Asp Glu Val Glu
                  35                  40                  45

 Tyr Glu Pro Arg Gly Ser Arg Leu Leu Val Arg Gly Leu Gly Glu
                  50                  55                  60

 His Glu Met Glu Glu Asp Glu Glu Asp Tyr Glu Ser Ser Ala Lys
                  65                  70                  75

 Leu Leu Gly Met Ser Phe Met Asn Arg Ser Ser Gly Leu Arg Asn
                  80                  85                  90

 Ser Ala Thr Gly Tyr Arg Gln Ser Pro Asp Gly Ala Cys Ser Val
                  95                 100                 105

 Pro Ser Ala Arg Thr Met Val Val Cys Ala Phe Val Ile Val Val
                 110                 115                 120

 Ala Val Ser Val Ile Met Val Ile Tyr Leu Leu Pro Arg Cys Thr
                 125                 130                 135

 Phe Thr Lys Glu Gly Cys His Lys Lys Asn Gln Ser Ile Gly Leu
                 140                 145                 150

 Ile Gln Pro Phe Ala Thr Asn Gly Lys Leu Phe Pro Trp Ala Gln
                 155                 160                 165

 Ile Arg Leu Pro Thr Ala Val Val Pro Leu Arg Tyr Glu Leu Ser
                 170                 175                 180

 Leu His Pro Asn Leu Thr Ser Met Thr Phe Arg Gly Ser Val Thr
                 185                 190                 195

 Ile Ser Val Gln Ala Leu Gln Val Thr Trp Asn Ile Ile Leu His
                 200                 205                 210

 Ser Thr Gly His Asn Ile Ser Arg Val Thr Phe Met Ser Ala Val
                 215                 220                 225

 Ser Ser Gln Glu Lys Gln Ala Glu Ile Leu Glu Tyr Ala Tyr His
                 230                 235                 240

 Gly Gln Ile Ala Ile Val Ala Pro Glu Ala Leu Leu Ala Gly His
                 245                 250                 255

 Asn Tyr Thr Leu Lys Ile Glu Tyr Ser Ala Asn Ile Ser Ser Ser
                 260                 265                 270

 Tyr Tyr Gly Phe Tyr Gly Phe Ser Tyr Thr Asp Glu Ser Asn Glu
                 275                 280                 285

 Lys Lys Tyr Phe Ala Ala Thr Gln Phe Glu Pro Leu Ala Ala Arg
                 290                 295                 300

 Ser Ala Phe Pro Cys Phe Asp Glu Pro Ala Phe Lys Ala Thr Phe
                 305                 310                 315

 Ile Ile Lys Ile Ile Arg Asp Glu Gln Tyr Thr Ala Leu Ser Asn
                 320                 325                 330

 Met Pro Lys Lys Ser Ser Val Val Leu Asp Asp Gly Leu Val Gln
                 335                 340                 345

 Asp Glu Phe Ser Glu Ser Val Lys Met Ser Thr Tyr Leu Val Ala
                 350                 355                 360

 Phe Ile Val Gly Glu Met Lys Asn Leu Ser Gln Asp Val Asn Gly
                 365                 370                 375

 Thr Leu Val Ser Ile Tyr Ala Val Pro Glu Asn Ile Gly Gln Val
                 380                 385                 390

 His Tyr Ala Leu Glu Thr Thr Val Lys Leu Leu Glu Phe Phe Gln
                 395                 400                 405

 Asn Tyr Phe Glu Ile Gln Tyr Pro Leu Lys Lys Leu Asp Leu Val
                 410                 415                 420

 Ala Ile Pro Asp Phe Glu Ala Gly Ala Met Glu Asn Trp Gly Leu
                 425                 430                 435

 Leu Thr Phe Arg Glu Glu Thr Leu Leu Tyr Asp Ser Asn Thr Ser
                 440                 445                 450

 Ser Met Ala Asp Arg Lys Leu Val Thr Lys Ile Ile Ala His Glu
                 455                 460                 465

 Leu Ala His Gln Trp Phe Gly Asn Leu Val Thr Met Lys Trp Trp
                 470                 475                 480

 Asn Asp Leu Trp Leu Asn Glu Gly Phe Ala Thr Phe Met Glu Tyr
                 485                 490                 495

 Phe Ser Leu Glu Lys Ile Phe Lys Glu Leu Ser Ser Tyr Glu Asp
                 500                 505                 510

 Phe Leu Asp Ala Arg Phe Lys Thr Met Lys Lys Asp Ser Leu Asn
                 515                 520                 525

 Ser Ser His Pro Ile Ser Ser Ser Val Gln Ser Ser Glu Gln Ile
                 530                 535                 540

 Glu Glu Met Phe Asp Ser Leu Ser Tyr Phe Lys Gly Ser Ser Leu
                 545                 550                 555

 Leu Leu Met Leu Lys Thr Tyr Leu Ser Glu Asp Val Phe Gln His
                 560                 565                 570

 Ala Val Val Leu Tyr Leu His Asn His Ser Tyr Ala Ser Ile Gln
                 575                 580                 585

 Ser Asp Asp Leu Trp Asp Ser Phe Asn Glu Val Thr Asn Gln Thr
                 590                 595                 600

 Leu Asp Val Lys Arg Met Met Lys Thr Trp Thr Leu Gln Lys Gly
                 605                 610                 615

 Phe Pro Leu Val Thr Val Gln Lys Lys Gly Lys Glu Leu Phe Ile
                 620                 625                 630

 Gln Gln Glu Arg Phe Phe Leu Asn Met Lys Pro Glu Ile Gln Pro
                 635                 640                 645

 Ser Asp Thr Ser Tyr Leu Trp His Ile Pro Leu Ser Tyr Val Thr
                 650                 655                 660

 Glu Gly Arg Asn Tyr Ser Lys Tyr Gln Ser Val Ser Leu Leu Asp
                 665                 670                 675

 Lys Lys Ser Gly Val Ile Asn Leu Thr Glu Glu Val Leu Trp Val
                 680                 685                 690

 Lys Val Asn Ile Asn Met Asn Gly Tyr Tyr Ile Val His Tyr Ala
                 695                 700                 705

 Asp Asp Asp Trp Glu Ala Leu Ile His Gln Leu Lys Ile Asn Pro
                 710                 715                 720

 Tyr Val Leu Ser Asp Lys Asp Arg Ala Asn Leu Ile Asn Asn Ile
                 725                 730                 735

 Phe Glu Leu Ala Gly Leu Gly Lys Val Pro Leu Lys Arg Ala Phe
                 740                 745                 750

 Asp Leu Ile Asn Tyr Leu Gly Asn Glu Asn His Thr Ala Pro Ile
                 755                 760                 765

 Thr Glu Ala Leu Phe Gln Thr Asp Leu Ile Tyr Asn Leu Leu Glu
                 770                 775                 780

 Lys Leu Gly Tyr Met Asp Leu Ala Ser Arg Leu Val Thr Arg Val
                 785                 790                 795

 Phe Lys Leu Leu Gln Asn Gln Ile Gln Gln Gln Thr Trp Thr Asp
                 800                 805                 810

 Glu Gly Thr Pro Ser Met Arg Glu Leu Arg Ser Ala Leu Leu Glu
                 815                 820                 825

 Phe Ala Cys Thr His Asn Leu Gly Asn Cys Ser Thr Thr Ala Met
                 830                 835                 840

 Lys Leu Phe Asp Asp Trp Met Ala Ser Asn Gly Thr Gln Ser Leu
                 845                 850                 855

 Pro Thr Asp Val Met Thr Thr Val Phe Lys Val Gly Ala Lys Thr
                 860                 865                 870

 Asp Lys Gly Trp Ser Phe Leu Leu Gly Lys Tyr Ile Ser Ile Gly
                 875                 880                 885

 Ser Glu Ala Glu Lys Asn Lys Ile Leu Glu Ala Leu Ala Ser Ser
                 890                 895                 900

 Glu Asp Val Arg Lys Leu Tyr Trp Leu Met Lys Ser Ser Leu Asn
                 905                 910                 915

 Gly Asp Asn Phe Arg Thr Gln Lys Leu Ser Phe Ile Ile Arg Thr
                 920                 925                 930

 Val Gly Arg His Phe Pro Gly His Leu Leu Ala Trp Asp Phe Val
                 935                 940                 945

 Lys Glu Asn Trp Asn Lys Leu Val Gln Lys Phe Pro Leu Gly Ser
                 950                 955                 960

 Tyr Thr Ile Gln Asn Ile Val Ala Gly Ser Thr Tyr Leu Phe Ser
                 965                 970                 975

 Thr Lys Thr His Leu Ser Glu Val Gln Ala Phe Phe Glu Asn Gln
                 980                 985                 990

 Ser Glu Ala Thr Phe Arg Leu Arg Cys Val Gln Glu Ala Leu Glu
                 995                1000                1005

 Val Ile Gln Leu Asn Ile Gln Trp Met Glu Lys Asn Leu Lys Ser
                1010                1015                1020

 Leu Thr Trp Trp Leu
                1025

<210> 1699
<211> 924
<212> DNA
<213> Homo sapien

<400> 1699
 cagagcccca cgaaggacca gaacaagaca gagtgcctcc tgccgatcca 50

 aacatgagcc gcctgcccgt cctgctcctg ctccaactcc tggtccgccc 100

 cggactccaa gctcccatga cccagacaac gcccttgaag acaagctggg 150

 ttaactgctc taacatgatc gatgaaatta taacacactt aaagcagcca 200

 cctttgcctt tgctggactt caacaacctc aatggggaag accaagacat 250

 tctgatggaa aataaccttc gaaggccaaa cctggaggca ttcaacaggg 300

 ctgtcaagag tttacagaac gcatcagcaa ttgagagcat tcttaaaaat 350

 ctcctgccat gtctgcccct ggccacggcc gcacccacgc gacatccaat 400

 ccatatcaag gacggtgact ggaatgaatt ccggaggaaa ctgacgttct 450

 atctgaaaac ccttgagaat gcgcaggctc aacagacgac tttgagcctc 500

 gcgatctttt gagtccaacg tccagctcgt tctctgggcc ttctcaccac 550

 agagcctcgg gacatcaaaa acagcagaac ttctgaaacc tctgggtcat 600

 ctctcacaca ttccaggacc agaagcattt caccttttcc tgcggcatca 650

 gatgaattgt taattatcta atttctgaaa tgtgcagctc ccatttggcc 700

 ttgtgcggtt gtgttctcat ttttatccca ttgagactat ttatttatgt 750

 atgtatgtat ttatttattt attgcctgga gtgtgaactg tatttatttt 800

 agcagaggag ccatgtcctg ctgcttctgc aaaaaactca gagtggggtg 850

 gggagcatgt tcatttgtac ctcgagtttt aaactggttc ctagggatgt 900

 gtgagaataa actagactct gaac 924

<210> 1700
<211> 152
<212> PRT
<213> Homo sapien

<400> 1700
 Met Ser Arg Leu Pro Val Leu Leu Leu Leu Gln Leu Leu Val Arg
   1               5                  10                  15

 Pro Gly Leu Gln Ala Pro Met Thr Gln Thr Thr Pro Leu Lys Thr
                  20                  25                  30

 Ser Trp Val Asn Cys Ser Asn Met Ile Asp Glu Ile Ile Thr His
                  35                  40                  45

 Leu Lys Gln Pro Pro Leu Pro Leu Leu Asp Phe Asn Asn Leu Asn
                  50                  55                  60

 Gly Glu Asp Gln Asp Ile Leu Met Glu Asn Asn Leu Arg Arg Pro
                  65                  70                  75

 Asn Leu Glu Ala Phe Asn Arg Ala Val Lys Ser Leu Gln Asn Ala
                  80                  85                  90

 Ser Ala Ile Glu Ser Ile Leu Lys Asn Leu Leu Pro Cys Leu Pro
                  95                 100                 105

 Leu Ala Thr Ala Ala Pro Thr Arg His Pro Ile His Ile Lys Asp
                 110                 115                 120

 Gly Asp Trp Asn Glu Phe Arg Arg Lys Leu Thr Phe Tyr Leu Lys
                 125                 130                 135

 Thr Leu Glu Asn Ala Gln Ala Gln Gln Thr Thr Leu Ser Leu Ala
                 140                 145                 150

 Ile Phe


<210> 1701
<211> 816
<212> DNA
<213> Homo sapien

<400> 1701
 atgcactttc tttgccaaag gcaaacgcag aacgtttcag agccatgagg 50

 atgcttctgc atttgagttt gctagctctt ggagctgcct acgtgtatgc 100

 catccccaca gaaattccca caagtgcatt ggtgaaagag accttggcac 150

 tgctttctac tcatcgaact ctgctgatag ccaatgagac tctgaggatt 200

 cctgttcctg tacataaaaa tcaccaactg tgcactgaag aaatctttca 250

 gggaataggc acactggaga gtcaaactgt gcaagggggt actgtggaaa 300

 gactattcaa aaacttgtcc ttaataaaga aatacattga cggccaaaaa 350

 aaaaagtgtg gagaagaaag acggagagta aaccaattcc tagactacct 400

 gcaagagttt cttggtgtaa tgaacaccga gtggataata gaaagttgag 450

 actaaactgg tttgttgcag ccaaagattt tggaggagaa ggacatttta 500

 ctgcagtgag aatgagggcc aagaaagagt caggccttaa ttttcagtat 550

 aatttaactt cagagggaaa gtaaatattt caggcatact gacactttgc 600

 cagaaagcat aaaattctta aaatatattt cagatatcag aatcattgaa 650

 gtattttcct ccaggcaaaa ttgatatact tttttcttat ttaacttaac 700

 attctgtaaa atgtctgtta acttaatagt atttatgaaa tggttaagaa 750

 tttggtaaat tagtatttat ttaatgttat gttgtgttct aataaaacaa 800

 aaatagacaa ctgttc 816

<210> 1702
<211> 134
<212> PRT
<213> Homo sapien

<400> 1702
 Met Arg Met Leu Leu His Leu Ser Leu Leu Ala Leu Gly Ala Ala
   1               5                  10                  15

 Tyr Val Tyr Ala Ile Pro Thr Glu Ile Pro Thr Ser Ala Leu Val
                  20                  25                  30

 Lys Glu Thr Leu Ala Leu Leu Ser Thr His Arg Thr Leu Leu Ile
                  35                  40                  45

 Ala Asn Glu Thr Leu Arg Ile Pro Val Pro Val His Lys Asn His
                  50                  55                  60

 Gln Leu Cys Thr Glu Glu Ile Phe Gln Gly Ile Gly Thr Leu Glu
                  65                  70                  75

 Ser Gln Thr Val Gln Gly Gly Thr Val Glu Arg Leu Phe Lys Asn
                  80                  85                  90

 Leu Ser Leu Ile Lys Lys Tyr Ile Asp Gly Gln Lys Lys Lys Cys
                  95                 100                 105

 Gly Glu Glu Arg Arg Arg Val Asn Gln Phe Leu Asp Tyr Leu Gln
                 110                 115                 120

 Glu Phe Leu Gly Val Met Asn Thr Glu Trp Ile Ile Glu Ser
                 125                 130

<210> 1703
<211> 2574
<212> DNA
<213> Homo sapien

<400> 1703
 cagagccggc gcaggggaag cgcccggggc cccgggtgca gcagcgcccg 50

 ccgcctcccg ggcctccccg gcccgcagcc cggggtcccg ggccccgggg 100

 ccggcacctc tcgggctccg gctccccgcg cgcaagatgg ctgacccggc 150

 tgcggggccg ccgccgagcg agggcgagga gagcaccgtg cgcttcgccc 200

 gcaaaggcgc cctccggcag aagaacgtgc atgaggtcaa gaaccacaaa 250

 ttcaccgccc gcttcttcaa gcagcccacc ttctgcagcc actgcaccga 300

 cttcatctgg ggcttcggga agcagggatt ccagtgccaa gtttgctgct 350

 ttgtggtgca caagcggtgc catgaatttg tcacattctc ctgccctggc 400

 gctgacaagg gtccagcctc cgatgacccc cgcagcaaac acaagtttaa 450

 gatccacacg tactccagcc ccacgttttg tgaccactgt gggtcactgc 500

 tgtatggact catccaccag gggatgaaat gtgacacctg catgatgaat 550

 gtgcacaagc gctgcgtgat gaatgttccc agcctgtgtg gcacggacca 600

 cacggagcgc cgcggccgca tctacatcca ggcccacatc gacagggacg 650

 tcctcattgt cctcgtaaga gatgctaaaa accttgtacc tatggacccc 700

 aatggcctgt cagatcccta cgtaaaactg aaactgattc ccgatcccaa 750

 aagtgagagc aaacagaaga ccaaaaccat caaatgctcc ctcaaccctg 800

 agtggaatga gacatttaga tttcagctga aagaatcgga caaagacaga 850

 agactgtcag tagagatttg ggattgggat ttgaccagca ggaatgactt 900

 catgggatct ttgtcctttg ggatttctga acttcagaag gccagtgttg 950

 atggctggtt taagttactg agccaggagg aaggcgagta cttcaatgtg 1000

 cctgtgccac cagaaggaag tgaggccaat gaagaactgc ggcagaaatt 1050

 tgagagggcc aagatcagtc agggaaccaa ggtcccggaa gaaaagacga 1100

 ccaacactgt ctccaaattt gacaacaatg gcaacagaga ccggatgaaa 1150

 ctgaccgatt ttaacttcct aatggtgctg gggaaaggca gctttggcaa 1200

 ggtcatgctt tcagaacgaa aaggcacaga tgagctctat gctgtgaaga 1250

 tcctgaagaa ggacgttgtg atccaagatg atgacgtgga gtgcactatg 1300

 gtggagaagc gggtgttggc cctgcctggg aagccgccct tcctgaccca 1350

 gctccactcc tgcttccaga ccatggaccg cctgtacttt gtgatggagt 1400

 acgtgaatgg gggcgacctc atgtatcaca tccagcaagt cggccggttc 1450

 aaggagcccc atgctgtatt ttacgctgca gaaattgcca tcggtctgtt 1500

 cttcttacag agtaagggca tcatttaccg tgacctaaaa cttgacaacg 1550

 tgatgctcga ttctgaggga cacatcaaga ttgccgattt tggcatgtgt 1600

 aaggaaaaca tctgggatgg ggtgacaacc aagacattct gtggcactcc 1650

 agactacatc gcccccgaga taattgctta tcagccctat gggaagtccg 1700

 tggattggtg ggcatttgga gtcctgctgt atgaaatgtt ggctgggcag 1750

 gcaccctttg aaggggagga tgaagatgaa ctcttccaat ccatcatgga 1800

 acacaacgta gcctatccca agtctatgtc caaggaagct gtggccatct 1850

 gcaaagggct gatgaccaaa cacccaggca aacgtctggg ttgtggacct 1900

 gaaggcgaac gtgatatcaa agagcatgca tttttccggt atattgattg 1950

 ggagaaactt gaacgcaaag agatccagcc cccttataag ccaaaagcta 2000

 gagacaagag agacacctcc aacttcgaca aagagttcac cagacagcct 2050

 gtggaactga cccccactga taaactcttc atcatgaact tggaccaaaa 2100

 tgaatttgct ggcttctctt atactaaccc agagtttgtc attaatgtgt 2150

 aggtgaatgc aaactccatc gttgagcctg gggtgtaaga cttcaagcca 2200

 agcgtatgta tcaattctag tcttccagga ttcacggtgc acatgctggc 2250

 attcaacatg tggaaagctt gtcttagagg cctttcttgt atgtgtagct 2300

 tgctagtttg ttttctacat ttgaaaatgt ttagtttaga ataagcgcat 2350

 tatccaatta tagaggtaca attttccaaa cttccagaaa ctcatcaaat 2400

 gaacagacaa tgtcaaaact actgtgtctg ataccaaaat gcttcagtat 2450

 ttgtaatttt tcaagtcaga agctgatgtt cctggtaaaa gtttttacag 2500

 ttattctata atatcttctt tgaatgctaa gcatgagcga tatttttaaa 2550

 aattgtgagt aagcttcgga attc 2574

<210> 1704
<211> 671
<212> PRT
<213> Homo sapien

<400> 1704
 Met Ala Asp Pro Ala Ala Gly Pro Pro Pro Ser Glu Gly Glu Glu
   1               5                  10                  15

 Ser Thr Val Arg Phe Ala Arg Lys Gly Ala Leu Arg Gln Lys Asn
                  20                  25                  30

 Val His Glu Val Lys Asn His Lys Phe Thr Ala Arg Phe Phe Lys
                  35                  40                  45

 Gln Pro Thr Phe Cys Ser His Cys Thr Asp Phe Ile Trp Gly Phe
                  50                  55                  60

 Gly Lys Gln Gly Phe Gln Cys Gln Val Cys Cys Phe Val Val His
                  65                  70                  75

 Lys Arg Cys His Glu Phe Val Thr Phe Ser Cys Pro Gly Ala Asp
                  80                  85                  90

 Lys Gly Pro Ala Ser Asp Asp Pro Arg Ser Lys His Lys Phe Lys
                  95                 100                 105

 Ile His Thr Tyr Ser Ser Pro Thr Phe Cys Asp His Cys Gly Ser
                 110                 115                 120

 Leu Leu Tyr Gly Leu Ile His Gln Gly Met Lys Cys Asp Thr Cys
                 125                 130                 135

 Met Met Asn Val His Lys Arg Cys Val Met Asn Val Pro Ser Leu
                 140                 145                 150

 Cys Gly Thr Asp His Thr Glu Arg Arg Gly Arg Ile Tyr Ile Gln
                 155                 160                 165

 Ala His Ile Asp Arg Asp Val Leu Ile Val Leu Val Arg Asp Ala
                 170                 175                 180

 Lys Asn Leu Val Pro Met Asp Pro Asn Gly Leu Ser Asp Pro Tyr
                 185                 190                 195

 Val Lys Leu Lys Leu Ile Pro Asp Pro Lys Ser Glu Ser Lys Gln
                 200                 205                 210

 Lys Thr Lys Thr Ile Lys Cys Ser Leu Asn Pro Glu Trp Asn Glu
                 215                 220                 225

 Thr Phe Arg Phe Gln Leu Lys Glu Ser Asp Lys Asp Arg Arg Leu
                 230                 235                 240

 Ser Val Glu Ile Trp Asp Trp Asp Leu Thr Ser Arg Asn Asp Phe
                 245                 250                 255

 Met Gly Ser Leu Ser Phe Gly Ile Ser Glu Leu Gln Lys Ala Ser
                 260                 265                 270

 Val Asp Gly Trp Phe Lys Leu Leu Ser Gln Glu Glu Gly Glu Tyr
                 275                 280                 285

 Phe Asn Val Pro Val Pro Pro Glu Gly Ser Glu Ala Asn Glu Glu
                 290                 295                 300

 Leu Arg Gln Lys Phe Glu Arg Ala Lys Ile Ser Gln Gly Thr Lys
                 305                 310                 315

 Val Pro Glu Glu Lys Thr Thr Asn Thr Val Ser Lys Phe Asp Asn
                 320                 325                 330

 Asn Gly Asn Arg Asp Arg Met Lys Leu Thr Asp Phe Asn Phe Leu
                 335                 340                 345

 Met Val Leu Gly Lys Gly Ser Phe Gly Lys Val Met Leu Ser Glu
                 350                 355                 360

 Arg Lys Gly Thr Asp Glu Leu Tyr Ala Val Lys Ile Leu Lys Lys
                 365                 370                 375

 Asp Val Val Ile Gln Asp Asp Asp Val Glu Cys Thr Met Val Glu
                 380                 385                 390

 Lys Arg Val Leu Ala Leu Pro Gly Lys Pro Pro Phe Leu Thr Gln
                 395                 400                 405

 Leu His Ser Cys Phe Gln Thr Met Asp Arg Leu Tyr Phe Val Met
                 410                 415                 420

 Glu Tyr Val Asn Gly Gly Asp Leu Met Tyr His Ile Gln Gln Val
                 425                 430                 435

 Gly Arg Phe Lys Glu Pro His Ala Val Phe Tyr Ala Ala Glu Ile
                 440                 445                 450

 Ala Ile Gly Leu Phe Phe Leu Gln Ser Lys Gly Ile Ile Tyr Arg
                 455                 460                 465

 Asp Leu Lys Leu Asp Asn Val Met Leu Asp Ser Glu Gly His Ile
                 470                 475                 480

 Lys Ile Ala Asp Phe Gly Met Cys Lys Glu Asn Ile Trp Asp Gly
                 485                 490                 495

 Val Thr Thr Lys Thr Phe Cys Gly Thr Pro Asp Tyr Ile Ala Pro
                 500                 505                 510

 Glu Ile Ile Ala Tyr Gln Pro Tyr Gly Lys Ser Val Asp Trp Trp
                 515                 520                 525

 Ala Phe Gly Val Leu Leu Tyr Glu Met Leu Ala Gly Gln Ala Pro
                 530                 535                 540

 Phe Glu Gly Glu Asp Glu Asp Glu Leu Phe Gln Ser Ile Met Glu
                 545                 550                 555

 His Asn Val Ala Tyr Pro Lys Ser Met Ser Lys Glu Ala Val Ala
                 560                 565                 570

 Ile Cys Lys Gly Leu Met Thr Lys His Pro Gly Lys Arg Leu Gly
                 575                 580                 585

 Cys Gly Pro Glu Gly Glu Arg Asp Ile Lys Glu His Ala Phe Phe
                 590                 595                 600

 Arg Tyr Ile Asp Trp Glu Lys Leu Glu Arg Lys Glu Ile Gln Pro
                 605                 610                 615

 Pro Tyr Lys Pro Lys Ala Arg Asp Lys Arg Asp Thr Ser Asn Phe
                 620                 625                 630

 Asp Lys Glu Phe Thr Arg Gln Pro Val Glu Leu Thr Pro Thr Asp
                 635                 640                 645

 Lys Leu Phe Ile Met Asn Leu Asp Gln Asn Glu Phe Ala Gly Phe
                 650                 655                 660

 Ser Tyr Thr Asn Pro Glu Phe Val Ile Asn Val
                 665                 670

<210> 1705
<211> 5635
<212> DNA
<213> Homo sapien

<400> 1705
 ataaatgacg tgccgagaga gcgagcgaac gcgcagccgg gagagcggag 50

 tctcctgcct cccgcccccc acccctccag ctcctgctcc tcctccgctc 100

 cccatacaca gacgcgctca cacccgctcc ctcactcgca cacacagaca 150

 caagcgcgca cacaggctcc gcacacacac ttcgctctcc cgcgcgctca 200

 cacccctctt gccctgagcc cttgccggtg cagcgcggcg ccgcagctgg 250

 acgcccctcc cgggctcact ttgcaacgct gacggtgccg gcagtggccg 300

 tggaggtggg aacagcggcg gcatcctccc ccctggtcac agcccaagcc 350

 aggacgcccg cggaacctct cggctgtgct ctcccatgag tcgggatcgc 400

 agcatccccc accagccgct caccgcctcc gggagccgct gggcttgtac 450

 accgcagccc ttccgggaca gcagctgtga ctccccccca gtgcagattt 500

 cgggacagct ctctagaaac tcgctctaaa gacggaaccg ccacagcact 550

 caaagcccac tgcggaagag ggcagcccgg caagcccggg ccctgagcct 600

 ggacccttag cggtgccggg cagcactgcc ggcgcttcgc ctcgccggac 650

 gtccgctcct cctacactct cagcctccgc tggagagacc cccagcccca 700

 ccattcagcg cgcaagatac cctgcagata tgccctgcgt ccaagcccaa 750

 tatagccctt cccctccagg ttccagttat gcggcgcaga catacagctc 800

 ggaatacacc acggagatca tgaaccccga ctacaccaag ctgaccatgg 850

 accttggcag cactgagatc acggctacag ccaccacgtc cctgcccagc 900

 atcagtacct tcgtggaggg ctactcgagc aactacgaac tcaagccttc 950

 ctgcgtgtac caaatgcagc ggcccttgat caaagtggag gaggggcggg 1000

 cgcccagcta ccatcaccat caccaccacc accaccacca ccaccaccat 1050

 caccagcagc agcatcagca gccatccatt cctccagcct ccagcccgga 1100

 ggacgaggtg ctgcccagca cctccatgta cttcaagcag tccccaccgt 1150

 ccacccccac cacgccggcc ttccccccgc aggcgggggc gttatgggac 1200

 gaggcactgc cctcggcgcc cggctgcatc gcacccggcc cgctgctgga 1250

 cccgccgatg aaggcggtcc ccacggtggc cggcgcgcgc ttcccgctct 1300

 tccacttcaa gccctcgccg ccgcatcccc ccgcgcccag cccggccggc 1350

 ggccaccacc tcggctacga cccgacggcc gctgccgcgc tcagcctgcc 1400

 gctgggagcc gcagccgccg cgggcagcca ggccgccgcg cttgagagcc 1450

 acccgtacgg gctgccgctg gccaagaggg cggccccgct ggccttcccg 1500

 cctctcggcc tcacgccctc ccctaccgcg tccagcctgc tgggcgagag 1550

 tcccagcctg ccgtcgccgc ccagcaggag ctcgtcgtct ggcgagggca 1600

 cgtgtgccgt gtgcggggac aacgccgcct gccagcacta cggcgtgcga 1650

 acctgcgagg gctgcaaggg ctttttcaag agaacagtgc agaaaaatgc 1700

 aaaatatgtt tgcctggcaa ataaaaactg cccagtagac aagagacgtc 1750

 gaaaccgatg tcagtactgt cgatttcaga agtgtctcag tgttggaatg 1800

 gtaaaagaag ttgtccgtac agatagtctg aaagggagga gaggtcgtct 1850

 gccttccaaa ccaaagagcc cattacaaca ggaaccttct cagccctctc 1900

 caccttctcc tccaatctgc atgatgaatg cccttgtccg agctttaaca 1950

 gactcaacac ccagagatct tgattattcc agatactgtc ccactgacca 2000

 ggctgctgca ggcacagatg ctgagcatgt gcaacaattc tacaacctcc 2050

 tgacagcctc cattgatgta tccagaagct gggcagaaaa gattccggga 2100

 tttactgatc tccccaaaga agatcagaca ttacttattg aatcagcctt 2150

 tttggagctg tttgtcctca gactttccat caggtcaaac actgctgaag 2200

 ataagtttgt gttctgcaat ggacttgtcc tgcatcgact tcagtgcctt 2250

 cgtggatttg gggagtggct cgactctatt aaagactttt ccttaaattt 2300

 gcagagcctg aaccttgata tccaagcctt agcctgcctg tcagcactga 2350

 gcatgatcac agaaagacat gggttaaaag aaccaaagag agtcgaagag 2400

 ctatgcaaca agatcacaag cagtttaaaa gaccaccaga gtaagggaca 2450

 ggctctggag cccaccgagt ccaaggtcct gggtgccctg gtagaactga 2500

 ggaagatctg caccctgggc ctccagcgca tcttctacct gaagctggaa 2550

 gacttggtgt ctccaccttc catcattgac aagctcttcc tggacaccct 2600

 acctttctaa tcaggagcag tggagcagtg agctgcctcc tctcctagca 2650

 cctgcttgct acgcagcaaa gggataggtt tggaaaccta tcatttcctg 2700

 tccttcctta agaggaaaag cagctcctgt agaaagcaaa gactttcttt 2750

 tttttctggc tcttttcctt acaacctaaa gccagaaaac ttgcagagta 2800

 ttgtgttggg gttgtgtttt atatttaggc attgggggat ggggtgggag 2850

 ggggttatag ttcatgaggg ttttctaaga aattgctaac aaagcacttt 2900

 tggacaatgc tatcccagca ggaaaaaaaa ggataatata actgttttaa 2950

 aactctttct ggggaatcca attatagttg ctttgtattt aaaaacaaga 3000

 acagccaagg gttgttcgcc agggtaggat gtgtcttaaa gattggtccc 3050

 ttgaaaatat gcttcctgta tcaaaggtac gtatgtggtg caaacaaggc 3100

 agaaacttcc ttttaatttc cttcttcctt tattttaaca aatggtgaaa 3150

 gatggaggat tacctacaaa tcagacatgg caaaacaata atggctgttt 3200

 gcttccataa acaagtgcaa ttttttaaag tgctgtctta ctaagtcttg 3250

 tttattaact ctcctttatt ctatatggaa ataaaaagga ggcagtcatg 3300

 ttagcaaatg acacgttaat atccctagca gaggctgtgt tcaccttccc 3350

 tgtcgatccc ttctgaggta tggcccatcc aagactttta ggccattctt 3400

 gatggaacca gatccctgcc ctgactgtcc agctatcctg aaagtggatc 3450

 agattataaa ctggattaca tgtaactgtt ttggttgtgt tctatcaacc 3500

 ccaccagagt tccctaaact tgcttcagtt atagtaactg actggtatat 3550

 tcattcagaa gcgccataag tcagttgagt atttgatccc tagataagaa 3600

 catgcaaatc agcaggaact ggtcatacag ggtaagcacc agggacaata 3650

 aggattttta tagatataat ttaatttttg ttattggtta aggagacaat 3700

 tttggagagc aagcaaatct ttttaaaaaa tagtatgaat gtgaatacta 3750

 gaaaagattt aaaaaatagt atgagtgtga gtactaggaa ggattagtgg 3800

 gctgcgtttc aacattccgt gttcgtactc ccttttgtat gtttctactg 3850

 ttaatgccat attactatga gataatttgt tgcatagtgt ccttatttgt 3900

 ataaacattt gtatgcacgt tatattgtaa tagctttgcc tgtatttatt 3950

 gcaagaccac cagctcctgg aagctgagtt acagagtaat taaatggggt 4000

 gttcacagtg acttggatac accaattaga aattaaataa gcaaatatat 4050

 atatatatat aaatatagca ggttacatat atatatttat aatgtgtctt 4100

 tttattaacc atttgtacaa taaatgtcac ttcccatgcc gttattttat 4150

 ggttcatttg cagtgacttt taaggcagta ctgtttagca ctttgatatt 4200

 aaaattttgc ttatgttttg ctaaattcga ataatgtttg aagattttta 4250

 ggtctaaaag tctttatatt atatactctg tatcaagtca aaatatcttt 4300

 ggccattttg ctaagaaaca aactttgaat gtcaaactga tgtcacagta 4350

 gtttttgtta gctttaaatc atttttgctt tagtcttttt aaaggaaaat 4400

 aacaaaacta tgctgtttat attgtcatta aattatacaa tcaaacaaat 4450

 gccaaatgaa ttgcctaatt gctgcaaagt ataacccaga taggaaatca 4500

 tatgtttttt tccaagagtc attctaatat ttgattatgt tatgtgtgct 4550

 tttatgaaag attgttattt ttatatatca agatgataga acctggaatg 4600

 ttaggatttt gaaatgttag acttggaagg ggcctggtct gtcaactagt 4650

 ccaacccctt aaaattcata gaggagcaaa ctggggccca ttgaagggtg 4700

 aagagttact caaggtcaaa cagctggtaa cagaatcaag actaagacct 4750

 aatttacctt tccatactct ttttttttct caacttcatc tatataaaat 4800

 caggctttta aacataacca ctaatattta cctgaagata accatgagta 4850

 aagtatactt ttgcattaat tttttgagct tatatgcaaa cataataaat 4900

 attattaaat atcaggaaag ctaacatttc atacaagata gcttcagacc 4950

 aaattcaaat tgaatttgaa taaattagaa atactgtgca tacataacct 5000

 tcttgtgcac catgagtatt tggaaagtta atccttgttt ttgtcgtgtc 5050

 tataaaggaa gaacaaaaca aaataaaaac agagccctag agaaatgctg 5100

 ttacttttta tttttacacc catcagattt aaggaaaaga ctttttagcc 5150

 attataatct agtggttgga aggaatgaag aagctttttt agtaataggt 5200

 ccagatatga gtgctaaaaa taaagatgat agcatgttct tctgtcttcc 5250

 atagttatta caactatgag agcctcccaa gtcatcttat caactcaact 5300

 cccttttttt tgtcttaatg ttgcacataa gtttatacag agtggatgac 5350

 cacactagca cagaagagaa caacatgtat taaagcaggt gattcctccc 5400

 cttggcggga gagctctctc agtgtgaaca tgccttctgt gggcggaaat 5450

 caggaagcca ccagctgtta atggagagtg ccttgctttt atttcagaca 5500

 gcagagtttt ccaaagtttc tctgctcctc taacagcatt gctctttagt 5550

 gtgtgttaac ctgtggtttg aaagaaatgc tcttgtacat taacaatgta 5600

 aatttaaatg attaaattac attttatcaa tggca 5635

<210> 1706
<211> 626
<212> PRT
<213> Homo sapien

<400> 1706
 Met Pro Cys Val Gln Ala Gln Tyr Ser Pro Ser Pro Pro Gly Ser
   1               5                  10                  15

 Ser Tyr Ala Ala Gln Thr Tyr Ser Ser Glu Tyr Thr Thr Glu Ile
                  20                  25                  30

 Met Asn Pro Asp Tyr Thr Lys Leu Thr Met Asp Leu Gly Ser Thr
                  35                  40                  45

 Glu Ile Thr Ala Thr Ala Thr Thr Ser Leu Pro Ser Ile Ser Thr
                  50                  55                  60

 Phe Val Glu Gly Tyr Ser Ser Asn Tyr Glu Leu Lys Pro Ser Cys
                  65                  70                  75

 Val Tyr Gln Met Gln Arg Pro Leu Ile Lys Val Glu Glu Gly Arg
                  80                  85                  90

 Ala Pro Ser Tyr His His His His His His His His His His His
                  95                 100                 105

 His His His Gln Gln Gln His Gln Gln Pro Ser Ile Pro Pro Ala
                 110                 115                 120

 Ser Ser Pro Glu Asp Glu Val Leu Pro Ser Thr Ser Met Tyr Phe
                 125                 130                 135

 Lys Gln Ser Pro Pro Ser Thr Pro Thr Thr Pro Ala Phe Pro Pro
                 140                 145                 150

 Gln Ala Gly Ala Leu Trp Asp Glu Ala Leu Pro Ser Ala Pro Gly
                 155                 160                 165

 Cys Ile Ala Pro Gly Pro Leu Leu Asp Pro Pro Met Lys Ala Val
                 170                 175                 180

 Pro Thr Val Ala Gly Ala Arg Phe Pro Leu Phe His Phe Lys Pro
                 185                 190                 195

 Ser Pro Pro His Pro Pro Ala Pro Ser Pro Ala Gly Gly His His
                 200                 205                 210

 Leu Gly Tyr Asp Pro Thr Ala Ala Ala Ala Leu Ser Leu Pro Leu
                 215                 220                 225

 Gly Ala Ala Ala Ala Ala Gly Ser Gln Ala Ala Ala Leu Glu Gly
                 230                 235                 240

 His Pro Tyr Gly Leu Pro Leu Ala Lys Arg Ala Ala Pro Leu Ala
                 245                 250                 255

 Phe Pro Pro Leu Gly Leu Thr Pro Ser Pro Thr Ala Ser Ser Leu
                 260                 265                 270

 Leu Gly Glu Ser Pro Ser Leu Pro Ser Pro Pro Ser Arg Ser Ser
                 275                 280                 285

 Ser Ser Gly Glu Gly Thr Cys Ala Val Cys Gly Asp Asn Ala Ala
                 290                 295                 300

 Cys Gln His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys Gly Phe
                 305                 310                 315

 Phe Lys Arg Thr Val Gln Lys Asn Ala Lys Tyr Val Cys Leu Ala
                 320                 325                 330

 Asn Lys Asn Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys Gln
                 335                 340                 345

 Tyr Cys Arg Phe Gln Lys Cys Leu Ser Val Gly Met Val Lys Glu
                 350                 355                 360

 Val Val Arg Thr Asp Ser Leu Lys Gly Arg Arg Gly Arg Leu Pro
                 365                 370                 375

 Ser Lys Pro Lys Ser Pro Leu Gln Gln Glu Pro Ser Gln Pro Ser
                 380                 385                 390

 Pro Pro Ser Pro Pro Ile Cys Met Met Asn Ala Leu Val Arg Ala
                 395                 400                 405

 Leu Thr Asp Ser Thr Pro Arg Asp Leu Asp Tyr Ser Arg Tyr Cys
                 410                 415                 420

 Pro Thr Asp Gln Ala Ala Ala Gly Thr Asp Ala Glu His Val Gln
                 425                 430                 435

 Gln Phe Tyr Asn Leu Leu Thr Ala Ser Ile Asp Val Ser Arg Ser
                 440                 445                 450

 Trp Ala Glu Arg Ile Pro Gly Phe Thr Asp Leu Pro Lys Glu Asp
                 455                 460                 465

 Gln Thr Leu Leu Ile Glu Ser Ala Phe Leu Glu Leu Phe Val Leu
                 470                 475                 480

 Arg Leu Ser Ile Arg Ser Asn Thr Ala Glu Asp Lys Phe Val Phe
                 485                 490                 495

 Cys Asn Gly Leu Val Leu His Arg Leu Gln Cys Leu Arg Gly Phe
                 500                 505                 510

 Gly Glu Trp Leu Asp Ser Ile Lys Asp Phe Ser Leu Asn Leu Gln
                 515                 520                 525

 Ser Leu Asn Leu Asp Ile Gln Ala Leu Ala Cys Leu Ser Ala Leu
                 530                 535                 540

 Ser Met Ile Thr Glu Arg His Gly Leu Lys Glu Pro Lys Arg Val
                 545                 550                 555

 Glu Glu Leu Cys Asn Lys Ile Thr Ser Ser Leu Lys Asp His Gln
                 560                 565                 570

 Ser Lys Gly Gln Ala Leu Glu Pro Asn Glu Ser Lys Val Leu Val
                 575                 580                 585

 Ala Leu Val Glu Leu Arg Lys Ile Cys Thr Leu Gly Leu Gln Arg
                 590                 595                 600

 Ile Phe Tyr Leu Lys Leu Glu Asp Leu Val Ser Pro Pro Ser Ile
                 605                 610                 615

 Ile Asp Lys Leu Phe Leu Asp Thr Leu Pro Phe
                 620                 625

<210> 1707
<211> 8093
<212> DNA
<213> Homo sapien

<400> 1707
 ctcagctccc tgtggtgggg gatggcagag gcttcccgct ccccgcagct 50

 ggtttgcaca gcctcccgac tgtgccgtgg tgtctccttc cctaaagtgg 100

 gacagtcgtt tctgtgtcct gctggcctct gaggaacaga cgtgtgtgag 150

 aggccttcag ggcctgatgg ctggggtggt gacagtgcct ggagaatggg 200

 tggggactgg aggggccagg tggctaacca ctctcctctt ccatggcagc 250

 ggagctggag ttcgcccaaa tcatcatcat cgtcgtggtg gtcacggtga 300

 tggtggtggt catcgtctgc ctgctgaacc actacaaagt ctccacgcgg 350

 tccttcatca accgcccgaa ccagagccgg aggcgggagg acgggctgcc 400

 gcaggaaggg tgcctgtggc cttcagacag cgccgcaccg cggctgggcg 450

 cctcggagat catgcatgcc ccgcggtcca gggacaggtt cacagcgccg 500

 tccttcatcc agagggatcg cttcagccgc ttccagccca cctaccccta 550

 tgtgcagcac gagattgatc ttcctcccac catctccctg tccgacggtg 600

 aagagccacc tccttaccag gggccctgca ccctgcagct ccgggaccct 650

 gaacagcaga tggaactcaa ccgagagtcc gtgagggccc cacccaaccg 700

 aaccatattt gacagtgatt taatagacat tgctatgtat agcgggggtc 750

 catgcccacc cagcagcaac tcgggcatca gtgcaagcac ctgcagcagt 800

 aacgggagga tggaggggcc accccccaca tacagcgagg tgatgggcca 850

 ccacccaggc gcctctttcc tccatcacca gcgcagcaac gcacacaggg 900

 gcagcagact gcagtttcag cagaacaatg cagagagcac aatagtaccc 950

 atcaaaggca aagataggaa gcctgggaac ctggtctgat tccttccaac 1000

 gtgcacttca gctggagaaa gaaaccaaga agggaagcgg ccgctgggcc 1050

 cctcctgcgc acagtgttgt tcagtttcac atggtacaaa taagtaaaac 1100

 caaatgagca aacacggtct ttgtttctga ttccttttag gggaattgca 1150

 tgcaaactag actgaaatga tacaaacttc catctggtct gaccgcaaac 1200

 agtgtttatt tggggacagg ggttgggatg ggggtgtggg caggggaaaa 1250

 cagagaacgg gatgctttga agataccatg aaataaaacc cacagaggta 1300

 tttgatgtat ttaattgtga aaggagactt tgcagataaa tgaggccaga 1350

 atggcatgtt ttataattaa ctgaataaag aaggaagcat tattatatat 1400

 tattgtgggg aagaaccagc cagttcgctt tttctcctaa ggtgtggact 1450

 tttattttgt tttaaaaata tgaatcaaaa ttcctgtgtt gtgtgccaag 1500

 gtataaagtg gagaagttag atgagtgcaa ggagctcctt tgtgttgtga 1550

 tgatgtgttt taaaagttgc actatcttaa tgttgaaaat atttacaagg 1600

 gaactgtttt acgtgaagtt ctgtatgttg tcttttcacc tgtggattgt 1650

 aatcaggccc aaggaatatc ctggagtggt ccccagaagc atccaagaaa 1700

 agatatttgg ggacgtagcc taacatttta ccaacttacg taaatcaaaa 1750

 aagtcattat tgttgcagga gtttgcatca aatagcagtg catcgctgaa 1800

 gcttttggag acttttggat ggaagataag atagggaaga ttaagttcca 1850

 gcatttctga cttgttattt tgagttactc tgctactctt aggctgcata 1900

 gtttatgaga aaatgaacac atgcatttat ggatccagta tcatgcagtg 1950

 ctgccctcat cctccagcag tgcaatttct tcagtaattt agattttttt 2000

 cactatagca tgaaatatat tcaaatacat accttatttt atgcaataaa 2050

 ttgtttaaaa tgcaaggtgg ttattctgca tactgttgaa atatgtgact 2100

 cctcagtata ttcccattgc ctctccccct ttcctcgaca gcttagttca 2150

 gttctgcagg gctgctcagt tcacaggagg ctcccagcag ccaccccaca 2200

 tccagcctac acagaacttt cgtgtgggag tggtgtgggt ggtggttttc 2250

 ttatgctttg gaagccccta gaaataatga cggaagaatg ccatgttgct 2300

 gatcgtggta ataagccatt gtgggttatt gtatgtcact agtattagca 2350

 tagcattctt aaaggaatgc agtgttcaaa acctacccaa attccccgca 2400

 ggattttacc aaacccttcc ccaggccagt tttgtactga aggcaagaac 2450

 tggacagtca gagaacagtg gagggggcaa gtgactgaag agcaccgggt 2500

 aaaaagcaca acatgcagtt aaaatgcaaa ctagaaaact aattttaaat 2550

 attgttagtt ttaatatttc ctgatattta caaatattca ttcttatata 2600

 caatgaaaaa aataactttc ttctgcagat gtaagcactg gcttttataa 2650

 gagcagcagc caacacgttt agcagacact gcgcgtggag aagggcttat 2700

 ctgcagtaca ctctgccatg tggagggtgg gcctctgtgg cctcttcaca 2750

 taacaagatg agctggaatg atgattccat gactcccacc tatgcagcct 2800

 taaagccaaa tccgcgtgtg tgtgtttgtg tctgtctgtg ggtctcgaag 2850

 gtgatccgtc ggtgcggtgg ctctgtgctg taactggaga gactgttcca 2900

 aaccccaaga gttgtctgat cctagtctgt tcccttctgc ttcttacctc 2950

 tgtagatagg tcactggttt ttgtttgttt gttttgagga ttggaatttc 3000

 cattacattc atcctttgca cacagtaaca tccacagaac tagtccaact 3050

 cttaaaagga gagaggaaaa acacaggcac cagttgtcag ctcatgctta 3100

 caacctgtgt ggaagtatat acagttgaga gtcacagtgg aggttctgag 3150

 actggattca gtcttgttcc agtgacagtt ggaaggcctc tgctggagag 3200

 acaccagctc tcagggcaga gattggcttg gggccagaag gaccctcccc 3250

 aaccctggag acaccctgaa ggttcactgg ctctccagat tagcctctct 3300

 tcctctgtca ggcaaagatg aggagcccgt gttcccatcg ggccctgctg 3350

 gcagggactt gcagtggatt cttggtcagg tgtgcccaca gatgcggagg 3400

 cgaggtgagt gattccatca tttcagttct cacctgcagt tttggtgaag 3450

 caggagatgc accccacagc tctagctctc aaatggcttc acagtcctta 3500

 cttctctacc tgcctcaaga aggggctcag agcagagact tgtgaattcc 3550

 ttagtaactg tgagtatatg aatgtgttgc acatgtccac agtattggcg 3600

 agataattac ataattcaga tacctttaat catctttcaa gaaagaggct 3650

 cctcccattc aaccacccta gagaactgcc tttgttaaat agttatttaa 3700

 agactcatac atatcaaacc atgactttga aaggtcttcg aggctggggc 3750

 tctgtaatga attagtttaa aagccaaggt cataacatga attgatggtc 3800

 aatttccctt cagcagaagg aaaaggtgat ttagatcagt agctcttttg 3850

 aaggttgtgg ctgacctgtt cataccgtgt cgcctcatgg ctagtgtggc 3900

 gttgaaagag tagcgactgg gaagatacaa cttacacagt ggggcctatt 3950

 gttctttcaa gaaccctttt tttagcttat agaacccatg ggtccagttt 4000

 agtaacgagt gatttaggca atcaatgata ggtttataat cttagattat 4050

 tccagcaaag tgtggattgc attgttagga agaacatttg gtgggaatga 4100

 acactcctgg gcataccgct gacttttgtc ccttgttccc ggtgtaggag 4150

 acccaaggca tcttgaatcc catctataag aacacaatct tccagcatac 4200

 gtttgctttt tcagaaactc tagcattctc tttaaatact gacgcaatcc 4250

 ttaatggaaa agagatttca tgaagcaaat tatgtatttc aatagttctt 4300

 ctatttttag tgtccaaaat ttactaatac agaagcttga caagcatgtc 4350

 ctcaccctcc ccaccacata aacacatgga cacacaccca agccacaaga 4400

 aatcccaaga gagcagaagc gaatttttaa aagatttatc gtgaggactg 4450

 catttccatt cactaatttt ggctcaaact tatgaggcag gaaatagggg 4500

 ccaacagtaa atgggggagg cctcctgaca ccagcagagg aattttgtac 4550

 ccaggcgagg acttcttgaa cttctgcgta tctccgtttg atctctttca 4600

 cctttatttc atcttcataa gaatgagaaa ggctcaaaag gaagcacttt 4650

 tagaaatctt ctctgaccta gaagaatcca tccaaatccc tgccttcctc 4700

 tctgaaccaa cagttccctt ctctgacagg gggccatcct ctatcttcca 4750

 tccagcggct cttcctttta ggaaggctct ggtgcagagc acttcaaata 4800

 tgtcctcagg ccagatactg attgctagta gagagacacc cggcacccag 4850

 tccgaagccc tccctcaaag gaccggctta tggcgttggt cactggcagg 4900

 ctcagagaca ttctactgtg ggcgcaggga gcccggcccc ccatgcagcc 4950

 atgactggat gcgcccccat ctcgggggct tgctgcactg cttgtttatt 5000

 gaattttgct acttagaatg gcaacattaa ctttgtgtac cattcatttt 5050

 ttaaaaattt tccaaagctc ggcagtgtat gaaagaaaaa actgggaaag 5100

 atacttggtt tctgttaact tttgtgttgc ttgcttaagt gattaaagcc 5150

 agtgcttgga gccaagcctt catgccacga acatgctcca cagcctgccc 5200

 tttgctctcc tgctcacact gaccaagaat gccgcgtgct tggcctactg 5250

 aggtgaaagg acaattgaat gacaggtggg caaagggaga acttcccctt 5300

 cttggtgcga ggaaagtcac aaatttaaaa atgttgcttc cagcccagat 5350

 cctaaatgct agttctcagc agctgcgtgg cttaccgttc gccatttcca 5400

 ccaccgccag ctgccagcac cgctacagat cacagagatg tgaacagaca 5450

 atggaaagca ctcttagcct tgcagtggtc tacatttttt aggaaccaat 5500

 atttcagcat tctttattac ccggcacgct gtgtcctttg cagagttcaa 5550

 gtttatgtta ctgccagggt cagacagtca tttgctgctg ctgctgctgc 5600

 tgctgctgct tctcgaactg gatgcattag gaagctgctg tctgagtgta 5650

 ggaatgtctt gctaagaaag caatgtcttc cttcatcctt ttctttcttc 5700

 cctctgcgtg tccttgtttt tgtgtaatgc gggagagggt tagagctata 5750

 gagattatat atacactatc cgtgcacatt atatatatgt agatataccc 5800

 ctatcatgtc agagatctgc atgtcagttt ttcagcaact aaggtgcctc 5850

 atgttctgag ttcagcagat ataggaacca agccgccccc tcctgcactt 5900

 gatgctccca cctttgttgt gcctcactta aaatggtgct tttttcagtt 5950

 gtctgtcttt tcttatgttt ttatttgtaa ggtgctgtat ataagttgaa 6000

 tatattatgc acatatccta cccaatgggt agaacaaaaa gttgttaata 6050

 ctgtaatata atgtatagat gataccaatt ttaacagaaa tggcatagaa 6100

 tttgtgaatg cctatgtgct ttgtcctctt ttgtaaggaa atttgcaaat 6150

 ggatgcatac agattaaagt ctatgtagtt tattttccta ttaaatatca 6200

 atattataac acaagagaaa gaagtgtgaa caaacaagca acagtttatg 6250

 accagcgtat atatagcaat ggaaagttgc atctttgctg tgaaaacact 6300

 ttaaagaaaa tactttttaa aaaatcccac agctttttgg ttgccactag 6350

 acgcttctta ttttaatcat tttagtaatg ctcagctgga ccagtgttag 6400

 ttatatttga gtcagaaaaa tgttgttttt caacttgctt tataatctcc 6450

 tgcatctatc tcctgctgta gcatcaygaa ggtgtcaggc aacagtgaaa 6500

 agtgcacatt tttgttgttg cagaaactgt gtcagaggaa taagtaaatc 6550

 agcctgcagc agaagacttt gttcagctcc agaggcatct gtgaccgtct 6600

 gtgtccaagt ctctctgtgc ctttttcttt tacaaactga agctgtggag 6650

 ccaatgaagt aacagtagag attgtaggga aagaatacct caggaaaaac 6700

 aaatacactt acaagaagac cctgttctta gaaaatgtgt ttagttatgg 6750

 gttagcacta gaagagactt ggctgtcagc cagccaagtg aaggacctct 6800

 catccattcc cattcatgtc ccatcataat acggacmcaa aaagcaaact 6850

 cggttttgcc atcagttaga aattacgttt tggattgtat attgttacat 6900

 ctctcttcca gcttagtttt tagtgtctga ttgtgacctc tgcatttatc 6950

 ttcaaatacc ctaattttaa aacaaaagaa caagaaaagt ttataacacc 7000

 atgttcacta aaaccacggt tgaatcttgg gtgtgggcat cctttcgagt 7050

 gttgtccata agagcagttc gtggaatttt gcccatctga cccatattat 7100

 cagcttattc tgccaccaga gtagagtcta ataaattcca aagtttttat 7150

 ttgctccatg gtgtatgttc tgactttgaa aatgtcagat tctataatca 7200

 tacccctaac atccaggaga caaatgacag attatcttta aactgaaatt 7250

 gactctacaa tgcaaccctt aatgctgaat ggattaaaaa agtcagccct 7300

 tttagtatct gtttgaaagg gccgtaaaaa gttgacactt ttgttgttgt 7350

 ggatcctgcg tgtctagacc cacgtgttgt ttccatcgta tactgtaggg 7400

 tgcacccctt gggattcatc attaagaact gaggctcact gttgtcagaa 7450

 acaaagctcc caccccccag gttcaacctt gtgggagaac tgttgagcat 7500

 gagaatgttc tagactcaga ggtactaaaa tttgttacca catcattgct 7550

 tcctttctac aggacgaatt gaggcttaaa ctttactgtt aatgatactg 7600

 gttcatttta atgtgcttgt tggtatgttg ctatttttca tttcatagct 7650

 ttcaaaaatc atgctaattg tatacttgtc tagtttaagg ctattttaaa 7700

 atatgtacaa tactattcac agcatttagt tcgtttaatt tttattataa 7750

 agcaatctac taaaaaagta caactgtatt tgaacttttc aatagttgtt 7800

 tgtgagctat gataatcaaa agtcattaaa gtctttttta acaaacattc 7850

 gtgcttactt ttcaacataa ttcccagtta tatacagaaa aagatttcca 7900

 cctgtcacgt atctgcctct tttacctgag caatggtgta gttcttagac 7950

 ctaaggtctg taattgcaat acttttaaag aaagatgttg ctctaagtgc 8000

 tgtttgttag ttatgaaatc agatttttct gcttgttctt aatgctgtgg 8050

 tcaaaccata gcacaaaatc attaaaaata atcagcggca tac 8093

<210> 1708
<211> 248
<212> PRT
<213> Homo sapien

<400> 1708
 Met Ala Ala Glu Leu Glu Phe Ala Gln Ile Ile Ile Ile Val Val
   1               5                  10                  15

 Val Val Thr Val Met Val Val Val Ile Val Cys Leu Leu Asn His
                  20                  25                  30

 Tyr Lys Val Ser Thr Arg Ser Phe Ile Asn Arg Pro Asn Gln Ser
                  35                  40                  45

 Arg Arg Arg Glu Asp Gly Leu Pro Gln Glu Gly Cys Leu Trp Pro
                  50                  55                  60

 Ser Asp Ser Ala Ala Pro Arg Leu Gly Ala Ser Glu Ile Met His
                  65                  70                  75

 Ala Pro Arg Ser Arg Asp Arg Phe Thr Ala Pro Ser Phe Ile Gln
                  80                  85                  90

 Arg Asp Arg Phe Ser Arg Phe Gln Pro Thr Tyr Pro Tyr Val Gln
                  95                 100                 105

 His Glu Ile Asp Leu Pro Pro Thr Ile Ser Leu Ser Asp Gly Glu
                 110                 115                 120

 Glu Pro Pro Pro Tyr Gln Gly Pro Cys Thr Leu Gln Leu Arg Asp
                 125                 130                 135

 Pro Glu Gln Gln Met Glu Leu Asn Arg Glu Ser Val Arg Ala Pro
                 140                 145                 150

 Pro Asn Arg Thr Ile Phe Asp Ser Asp Leu Ile Asp Ile Ala Met
                 155                 160                 165

 Tyr Ser Gly Gly Pro Cys Pro Pro Ser Ser Asn Ser Gly Ile Ser
                 170                 175                 180

 Ala Ser Thr Cys Ser Ser Asn Gly Arg Met Glu Gly Pro Pro Pro
                 185                 190                 195

 Thr Tyr Ser Glu Val Met Gly His His Pro Gly Ala Ser Phe Leu
                 200                 205                 210

 His His Gln Arg Ser Asn Ala His Arg Gly Ser Arg Leu Gln Phe
                 215                 220                 225

 Gln Gln Asn Asn Ala Glu Ser Thr Ile Val Pro Ile Lys Gly Lys
                 230                 235                 240

 Asp Arg Lys Pro Gly Asn Leu Val
                 245

<210> 1709
<211> 7193
<212> DNA
<213> Homo sapien

<400> 1709
 agaataaggg cagggaccgc ggctcctatc tcttggtgat ccccttcccc 50

 attccgcccc cgcctcaacg cccagcacag tgccctgcac acagtagtcg 100

 ctcaataaat gttcgtggat gatgatgatg atgatgatga aaaaaatgca 150

 gcatcaacgg cagcagcaag cggaccacgc gaacgaggca aactatgcaa 200

 gaggcaccag acttcctctt tctggtgaag gaccaacttc tcagccgaat 250

 agctccaagc aaactgtcct gtcttggcaa gctgcaatcg atgctgctag 300

 acaggccaag gctgcccaaa ctatgagcac ctctgcaccc ccacctgtag 350

 gatctctctc ccaaagaaaa cgtcagcaat acgccaagag caaaaaacag 400

 ggtaactcgt ccaacagccg acctgcccgc gcccttttct gtttatcact 450

 caataacccc atccgaagag cctgcattag tatagtggaa tggaaaccat 500

 ttgacatatt tatattattg gctatttttg ccaattgtgt ggccttagct 550

 atttacatcc cattccctga agatgattct aattcaacaa atcataactt 600

 ggaaaaagta gaatatgcct tcctgattat ttttacagtc gagacatttt 650

 tgaagattat agcgtatgga ttattgctac atcctaatgc ttatgttagg 700

 aatggatgga atttactgga ttttgttata gtaatagtag gattgtttag 750

 tgtaattttg gaacaattaa ccaaagaaac agaaggcggg aaccactcaa 800

 gcggcaaatc tggaggcttt gatgtcaaag ccctccgtgc ctttcgagtg 850

 ttgcgaccac ttcgactagt gtcaggggtg cccagtttac aagttgtcct 900

 gaactccatt ataaaagcca tggttcccct ccttcacata gcccttttgg 950

 tattatttgt aatcataatc tatgctatta taggattgga actttttatt 1000

 ggaaaaatgc acaaaacatg tttttttgct gactcagata tcgtagctga 1050

 agaggaccca gctccatgtg cgttctcagg gaatggacgc cagtgtactg 1100

 ccaatggcac ggaatgtagg agtggctggg ttggcccgaa cggaggcatc 1150

 accaactttg ataactttgc ctttgccatg cttactgtgt ttcagtgcat 1200

 caccatggag ggctggacag acgtgctcta ctgggtaaat gatgcgatag 1250

 gatgggaatg gccatgggtg tattttgtta gtctgatcat ccttggctca 1300

 tttttcgtcc ttaacctggt tcttggtgtc cttagtggag aattctcaaa 1350

 ggaaagagag aaggcaaaag cacggggaga tttccagaag ctccgggaga 1400

 agcagcagct ggaggaggat ctaaagggct acttggattg gatcacccaa 1450

 gctgaggaca tcgatccgga gaatgaggaa gaaggaggag aggaaggcaa 1500

 acgaaatact agcatgccca ccagcgagac tgagtctgtg aacacagaga 1550

 acgtcagcgg tgaaggcgag aaccgaggct gctgtggaag tctctggtgc 1600

 tggtggagac ggagaggcgc ggccaaggcg gggccctctg ggtgtcggcg 1650

 gtggggtcaa gccatctcaa aatccaaact cagccgacgc tggcgtcgct 1700

 ggaaccgatt caatcgcaga agatgtaggg ccgccgtgaa gtctgtcacg 1750

 ttttactggc tggttatcgt cctggtgttt ctgaacacct taaccatttc 1800

 ctctgagcac tacaatcagc cagattggtt gacacagatt caagatattg 1850

 ccaacaaagt cctcttggct ctgttcacct gcgagatgct ggtaaaaatg 1900

 tacagcttgg gcctccaagc atatttcgtc tctcttttca accggtttga 1950

 ttgcttcgtg gtgtgtggtg gaatcactga gacgatcctg gtggaactgg 2000

 aaatcatgtc tcccctgggg atctctgtgt ttcggtgtgt gcgcctctta 2050

 agaatcttca aagtgaccag gcactggact tccctgagca acttagtggc 2100

 atccttatta aactccatga agtccatcgc ttcgctgttg cttctgcttt 2150

 ttctcttcat tatcatcttt tccttgcttg ggatgcagct gtttggcggc 2200

 aagtttaatt ttgatgaaac gcaaaccaag cggagcacct ttgacaattt 2250

 ccctcaagca cttctcacag tgttccagat cctgacaggc gaagactgga 2300

 atgctgtgat gtacgatggc atcatggctt acgggggccc atcctcttca 2350

 ggaatgatcg tctgcatcta cttcatcatc ctcttcattt gtggtaacta 2400

 tattctactg aatgtcttct tggccatcgc tgtagacaat ttggctgatg 2450

 ctgaaagtct gaacactgct cagaaagaag aagcggaaga aaaggagagg 2500

 aaaaagattg ccagaaaaga gagcctagaa aataaaaaga acaacaaacc 2550

 agaagtcaac cagatagcca acagtgacaa caaggttaca attgatgact 2600

 atagagaaga ggatgaagac aaggacccct atccgccttg cgatgtgcca 2650

 gtaggggaag aggaagagga agaggaggag gatgaacctg aggttcctgc 2700

 cggaccccgt cctcgaagga tctcggagtt gaacatgaag gaaaaaattg 2750

 cccccatccc tgaagggagc gctttcttca ttcttagcaa gaccaacccg 2800

 atccgcgtag gctgccacaa gctcatcaac caccacatct tcaccaacct 2850

 catccttgtc ttcatcatgc tgagcagcgc tgccctggcc gcagaggacc 2900

 ccatccgcag ccactccttc cggaacacga tactgggtta ctttgactat 2950

 gccttcacag ccatctttac tgttgagatc ctgttgaaga tgacaacttt 3000

 tggagctttc ctccacaaag gggccttctg caggaactac ttcaatttgc 3050

 tggatatgct ggtggttggg gtgtctctgg tgtcatttgg gattcaatcc 3100

 agtgccatct ccgttgtgaa gattctgagg gtcttaaggg tcctgcgtcc 3150

 cctcagggcc atcaacagag caaaaggact taagcacgtg gtccagtgcg 3200

 tcttcgtggc catccggacc atcggcaaca tcatgatcgt cactaccctc 3250

 ctgcagttca tgtttgcctg tatcggggtc cagttgttca aggggaagtt 3300

 ctatcgctgt acggatgaag ccaaaagtaa ccctgaagaa tgcaggggac 3350

 ttttcatcct ctacaaggat ggggatgttg acagtcctgt ggtccgtgaa 3400

 cggatctggc aaaacagtga tttcaacttc gacaacgtcc tctctgctat 3450

 gatggcgctc ttcacagtct ccacgtttga gggctggcct gcgttgctgt 3500

 ataaagccat cgactcgaat ggagagaaca tcggcccaat ctacaaccac 3550

 cgcgtggaga tctccatctt cttcatcatc tacatcatca ttgtagcttt 3600

 cttcatgatg aacatctttg tgggctttgt catcgttaca tttcaggaac 3650

 aaggagaaaa agagtataag aactgtgagc tggacaaaaa tcagcgtcag 3700

 tgtgttgaat acgccttgaa agcacgtccc ttgcggagat acatccccaa 3750

 aaacccctac cagtacaagt tctggtacgt ggtgaactct tcgcctttcg 3800

 aatacatgat gtttgtcctc atcatgctca acacactctg cttggccatg 3850

 cagcactacg agcagtccaa gatgttcaat gatgccatgg acattctgaa 3900

 catggtcttc accggggtgt tcaccgtcga gatggttttg aaagtcatcg 3950

 catttaagcc taaggggtat tttagtgacg cctggaacac gtttgactcc 4000

 ctcatcgtaa tcggcagcat tatagacgtg gccctcagcg aagcggaccc 4050

 aactgaaagt gaaaatgtcc ctgtcccaac tgctacacct gggaactctg 4100

 aagagagcaa tagaatctcc atcacctttt tccgtctttt ccgagtgatg 4150

 cgattggtga agcttctcag caggggggaa ggcatccgga cattgctgtg 4200

 gacttttatt aagtcctttc aggcgctccc gtatgtggcc ctcctcatag 4250

 ccatgctgtt cttcatctat gcggtcattg gcatgcagat gtttgggaaa 4300

 gttgccatga gagataacaa ccagatcaat aggaacaata acttccagac 4350

 gtttccccag gcggtgctgc tgctcttcag gtgtgcaaca ggtgaggcct 4400

 ggcaggagat catgctggcc tgtctcccag ggaagctctg tgaccctgag 4450

 tcagattaca accccgggga ggagtataca tgtgggagca actttgccat 4500

 tgtctatttc atcagttttt acatgctctg tgcatttctg atcatcaatc 4550

 tgtttgtggc tgtcatcatg gataatttcg actatctgac ccgggactgg 4600

 tctattttgg ggcctcacca tttagatgaa ttcaaaagaa tatggtcaga 4650

 atatgaccct gaggcaaagg gaaggataaa acaccttgat gtggtcactc 4700

 tgcttcgacg catccagcct cccctggggt ttgggaagtt atgtccacac 4750

 agggtagcgt gcaagagatt agttgccatg aacatgcctc tcaacagtga 4800

 cgggacagtc atgtttaatg caaccctgtt tgctttggtt cgaacggctc 4850

 ttaagatcaa gaccgaaggg aacctggagc aagctaatga agaacttcgg 4900

 gctgtgataa agaaaatttg gaagaaaacc agcatgaaat tacttgacca 4950

 agttgtccct ccagctggtg atgatgaggt aaccgtgggg aagttctatg 5000

 ccactttcct gatacaggac tactttagga aattcaagaa acggaaagaa 5050

 caaggactgg tgggaaagta ccctgcgaag aacaccacaa ttgccctaca 5100

 ggcgggatta aggacactgc atgacattgg gccagaaatc cggcgtgcta 5150

 tatcgtgtga tttgcaagat gacgagcctg aggaaacaaa acgagaagaa 5200

 gaagatgatg tgttcaaaag aaatggtgcc ctgcttggaa accatgtcaa 5250

 tcatgttaat agtgatagga gagattccct tcagcagacc aataccaccc 5300

 accgtcccct gcatgtccaa aggccttcaa ttccacctgc aagtgatact 5350

 gagaaaccgc tgtttcctcc agcaggaaat tcggtgtgtc ataaccatca 5400

 taaccataat tccataggaa agcaagttcc cacctcaaca aatgccaatc 5450

 tcaataatgc caatatgtcc aaagctgccc atggaaagcg gcccagcatt 5500

 gggaaccttg agcatgtgtc tgaaaatggg catcattctt cccacaagca 5550

 tgaccgggag cctcagagaa ggtccagtgt gaaaagaacc cgctattatg 5600

 aaacttacat taggtccgac tcaggagatg aacagctccc aactatttgc 5650

 cgggaagacc cagagataca tggctatttc agggaccccc actgcttggg 5700

 ggagcaggag tatttcagta gtgaggaatg ctacgaggat gacagctcgc 5750

 ccacctggag caggcaaaac tatggctact acagcagata cccaggcaga 5800

 aacatcgact ctgagaggcc ccgaggctac catcatcccc aaggattctt 5850

 ggaggacgat gactcgcccg tttgctatga ttcacggaga tctccaagga 5900

 gacgcctact acctcccacc ccagcatccc accggagatc ctccttcaac 5950

 tttgagtgcc tgcgccggca gagcagccag gaagaggtcc cgtcgtctcc 6000

 catcttcccc catcgcacgg ccctgcctct gcatctaatg cagcaacaga 6050

 tcatggcagt tgccggccta gattcaagta aagcccagaa gtactcaccg 6100

 agtcactcga cccggtcgtg ggccacccct ccagcaaccc ctccctaccg 6150

 ggactggaca ccgtgctaca cccccctgat ccaagtggag cagtcagagg 6200

 ccctggacca ggtgaacggc agcctgccgt ccctgcaccg cagctcctgg 6250

 tacacagacg agcccgacat ctcctaccgg actttcacac cagccagcct 6300

 gactgtcccc agcagcttcc ggaacaaaaa cagcgacaag cagaggagtg 6350

 cggacagctt ggtggaggca gtcctgatat ccgaaggctt gggacgctat 6400

 gcaagggacc caaaatttgt gtcagcaaca aaacacgaaa tcgctgatgc 6450

 ctgtgacctc accatcgacg agatggagag tgcagccagc accctgctta 6500

 atgggaacgt gcgtccccga gccaacgggg atgtgggccc cctctcacac 6550

 cggcaggact atgagctaca ggactttggt cctggctaca gcgacgaaga 6600

 gccagaccct gggagggatg aggaggacct ggcggatgaa atgatatgca 6650

 tcaccacctt gtagccccca gcgaggggca gactggctct ggcctcaggt 6700

 ggggcgcagg agagccaggg gaaaagtgcc tcatagttag gaaagtttag 6750

 gcactagttg ggagtaatat tcaattaatt agacttttgt ataagagatg 6800

 tcatgcctca agaaagccat aaacctggta ggaacaggtc ccaagcggtt 6850

 gagcctggca gagtaccatg cgctcggccc cagctgcagg aaacagcagg 6900

 ccccgccctc tcacagagga tgggtgagga ggccagacct gccctgcccc 6950

 attgtccaga tgggcactgc tgtggagtct gcttctccca tgtaccaggg 7000

 caccaggccc acccaactga aggcatggcg gcggggtgca ggggaaagtt 7050

 aaaggtgatg acgatcatca cacctcgtgt cgttacctca gccatcggtc 7100

 tagcatatca gtcactgggc ccaacatatc catttttaaa ccctttcccc 7150

 caaatacact gcgtcctggt tcctgtttag ctgttctgaa ata 7193

<210> 1710
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1710
 Met Met Met Met Met Met Met Lys Lys Met Gln His Gln Arg Gln
   1               5                  10                  15

 Gln Gln Ala Asp His Ala Asn Glu Ala Asn Tyr Ala Arg Gly Thr
                  20                  25                  30

 Arg Leu Pro Leu Ser Gly Glu Gly Pro Thr Ser Gln Pro Asn Ser
                  35                  40                  45

 Ser Lys Gln Thr Val Leu Ser Trp Gln Ala Ala Ile Asp Ala Ala
                  50                  55                  60

 Arg Gln Ala Lys Ala Ala Gln Thr Met Ser Thr Ser Ala Pro Pro
                  65                  70                  75

 Pro Val Gly Ser Leu Ser Gln Arg Lys Arg Gln Gln Tyr Ala Lys
                  80                  85                  90

 Ser Lys Lys Gln Gly Asn Ser Ser Asn Ser Arg Pro Ala Arg Ala
                  95                 100                 105

 Leu Phe Cys Leu Ser Leu Asn Asn Pro Ile Arg Arg Ala Cys Ile
                 110                 115                 120

 Ser Ile Val Glu Trp Lys Pro Phe Asp Ile Phe Ile Leu Leu Ala
                 125                 130                 135

 Ile Phe Ala Asn Cys Val Ala Leu Ala Ile Tyr Ile Pro Phe Pro
                 140                 145                 150

 Glu Asp Asp Ser Asn Ser Thr Asn His Asn Leu Glu Lys Val Glu
                 155                 160                 165

 Tyr Ala Phe Leu Ile Ile Phe Thr Val Glu Thr Phe Leu Lys Ile
                 170                 175                 180

 Ile Ala Tyr Gly Leu Leu Leu His Pro Asn Ala Tyr Val Arg Asn
                 185                 190                 195

 Gly Trp Asn Leu Leu Asp Phe Val Ile Val Ile Val Gly Leu Phe
                 200                 205                 210

 Ser Val Ile Leu Glu Gln Leu Thr Lys Glu Thr Glu Gly Gly Asn
                 215                 220                 225

 His Ser Ser Gly Lys Ser Gly Gly Phe Asp Val Lys Ala Leu Arg
                 230                 235                 240

 Ala Phe Arg Val Leu Arg Pro Leu Arg Leu Val Ser Gly Val Pro
                 245                 250                 255

 Ser Leu Gln Val Val Leu Asn Ser Ile Ile Lys Ala Met Val Pro
                 260                 265                 270

 Leu Leu His Ile Ala Leu Leu Val Leu Phe Val Ile Ile Ile Tyr
                 275                 280                 285

 Ala Ile Ile Gly Leu Glu Leu Phe Ile Gly Lys Met His Lys Thr
                 290                 295                 300

 Cys Phe Phe Ala Asp Ser Asp Ile Val Ala Glu Glu Asp Pro Ala
                 305                 310                 315

 Pro Cys Ala Phe Ser Gly Asn Gly Arg Gln Cys Thr Ala Asn Gly
                 320                 325                 330

 Thr Glu Cys Arg Ser Gly Trp Val Gly Pro Asn Gly Gly Ile Thr
                 335                 340                 345

 Asn Phe Asp Asn Phe Ala Phe Ala Met Leu Thr Val Phe Gln Cys
                 350                 355                 360

 Ile Thr Met Glu Gly Trp Thr Asp Val Leu Tyr Trp Val Asn Asp
                 365                 370                 375

 Ala Ile Gly Trp Glu Trp Pro Trp Val Tyr Phe Val Ser Leu Ile
                 380                 385                 390

 Ile Leu Gly Ser Phe Phe Val Leu Asn Leu Val Leu Gly Val Leu
                 395                 400                 405

 Ser Gly Glu Phe Ser Lys Glu Arg Glu Lys Ala Lys Ala Arg Gly
                 410                 415                 420

 Asp Phe Gln Lys Leu Arg Glu Lys Gln Gln Leu Glu Glu Asp Leu
                 425                 430                 435

 Lys Gly Tyr Leu Asp Trp Ile Thr Gln Ala Glu Asp Ile Asp Pro
                 440                 445                 450

 Glu Asn Glu Glu Glu Gly Gly Glu Glu Gly Lys Arg Asn Thr Ser
                 455                 460                 465

 Met Pro Thr Ser Glu Thr Glu Ser Val Asn Thr Glu Asn Val Ser
                 470                 475                 480

 Gly Glu Gly Glu Asn Arg Gly Cys Cys Gly Ser Leu Trp Cys Trp
                 485                 490                 495

 Trp Arg Arg Arg Gly Ala Ala Lys Ala Gly Pro Ser Gly Cys Arg
                 500                 505                 510

 Arg Trp Gly Gln Ala Ile Ser Lys Ser Lys Leu Ser Arg Arg Trp
                 515                 520                 525

 Arg Arg Trp Asn Arg Phe Asn Arg Arg Arg Cys Arg Ala Ala Val
                 530                 535                 540

 Lys Ser Val Thr Phe Tyr Trp Leu Val Ile Val Leu Val Phe Leu
                 545                 550                 555

 Asn Thr Leu Thr Ile Ser Ser Glu His Tyr Asn Gln Pro Asp Trp
                 560                 565                 570

 Leu Thr Gln Ile Gln Asp Ile Ala Asn Lys Val Leu Leu Ala Leu
                 575                 580                 585

 Phe Thr Cys Glu Met Leu Val Lys Met Tyr Ser Leu Gly Leu Gln
                 590                 595                 600

 Ala Tyr Phe Val Ser Leu Phe Asn Arg Phe Asp Cys Phe Val Val
                 605                 610                 615

 Cys Gly Gly Ile Thr Glu Thr Ile Leu Val Glu Leu Glu Ile Met
                 620                 625                 630

 Ser Pro Leu Gly Ile Ser Val Phe Arg Cys Val Arg Leu Leu Arg
                 635                 640                 645

 Ile Phe Lys Val Thr Arg His Trp Thr Ser Leu Ser Asn Leu Val
                 650                 655                 660

 Ala Ser Leu Leu Asn Ser Met Lys Ser Ile Ala Ser Leu Leu Leu
                 665                 670                 675

 Leu Leu Phe Leu Phe Ile Ile Ile Phe Ser Leu Leu Gly Met Gln
                 680                 685                 690

 Leu Phe Gly Gly Lys Phe Asn Phe Asp Glu Thr Gln Thr Lys Arg
                 695                 700                 705

 Ser Thr Phe Asp Asn Phe Pro Gln Ala Leu Leu Thr Val Phe Gln
                 710                 715                 720

 Ile Leu Thr Gly Glu Asp Trp Asn Ala Val Met Tyr Asp Gly Ile
                 725                 730                 735

 Met Ala Tyr Gly Gly Pro Ser Ser Ser Gly Met Ile Val Cys Ile
                 740                 745                 750

 Tyr Phe Ile Ile Leu Phe Ile Cys Gly Asn Tyr Ile Leu Leu Asn
                 755                 760                 765

 Val Phe Leu Ala Ile Ala Val Asp Asn Leu Ala Asp Ala Glu Ser
                 770                 775                 780

 Leu Asn Thr Ala Gln Lys Glu Glu Ala Glu Glu Lys Glu Arg Lys
                 785                 790                 795

 Lys Ile Ala Arg Lys Glu Ser Leu Glu Asn Lys Lys Asn Asn Lys
                 800                 805                 810

 Pro Glu Val Asn Gln Ile Ala Asn Ser Asp Asn Lys Val Thr Ile
                 815                 820                 825

 Asp Asp Tyr Arg Glu Glu Asp Glu Asp Lys Asp Pro Tyr Pro Pro
                 830                 835                 840

 Cys Asp Val Pro Val Gly Glu Glu Glu Glu Glu Glu Glu Glu Asp
                 845                 850                 855

 Glu Pro Glu Val Pro Ala Gly Pro Arg Pro Arg Arg Ile Ser Glu
                 860                 865                 870

 Leu Asn Met Lys Glu Lys Ile Ala Pro Ile Pro Glu Gly Ser Ala
                 875                 880                 885

 Phe Phe Ile Leu Ser Lys Thr Asn Pro Ile Arg Val Gly Cys His
                 890                 895                 900

 Lys Leu Ile Asn His His Ile Phe Thr Asn Leu Ile Leu Val Phe
                 905                 910                 915

 Ile Met Leu Ser Ser Ala Ala Leu Ala Ala Glu Asp Pro Ile Arg
                 920                 925                 930

 Ser His Ser Phe Arg Asn Thr Ile Leu Gly Tyr Phe Asp Tyr Ala
                 935                 940                 945

 Phe Thr Ala Ile Phe Thr Val Glu Ile Leu Leu Lys Met Thr Thr
                 950                 955                 960

 Phe Gly Ala Phe Leu His Lys Gly Ala Phe Cys Arg Asn Tyr Phe
                 965                 970                 975

 Asn Leu Leu Asp Met Leu Val Val Gly Val Ser Leu Val Ser Phe
                 980                 985                 990

 Gly Ile Gln Ser Ser Ala Ile Ser Val Val Lys Ile Leu Arg Val
                 995                1000                1005

 Leu Arg Val Leu Arg Pro Leu Arg Ala Ile Asn Arg Ala Lys Gly
                1010                1015                1020

 Leu Lys His Val Val Gln Cys Val Phe Val Ala Ile Arg Thr Ile
                1025                1030                1035

 Gly Asn Ile Met Ile Val Thr Thr Leu Leu Gln Phe Met Phe Ala
                1040                1045                1050

 Cys Ile Gly Val Gln Leu Phe Lys Gly Lys Phe Tyr Arg Cys Thr
                1055                1060                1065

 Asp Glu Ala Lys Ser Asn Pro Glu Glu Cys Arg Gly Leu Phe Ile
                1070                1075                1080

 Leu Tyr Lys Asp Gly Asp Val Asp Ser Pro Val Val Arg Glu Arg
                1085                1090                1095

 Ile Trp Gln Asn Ser Asp Phe Asn Phe Asp Asn Val Leu Ser Ala
                1100                1105                1110

 Met Met Ala Leu Phe Thr Val Ser Thr Phe Glu Gly Trp Pro Ala
                1115                1120                1125

 Leu Leu Tyr Lys Ala Ile Asp Ser Asn Gly Glu Asn Ile Gly Pro
                1130                1135                1140

 Ile Tyr Asn His Arg Val Glu Ile Ser Ile Phe Phe Ile Ile Tyr
                1145                1150                1155

 Ile Ile Ile Val Ala Phe Phe Met Met Asn Ile Phe Val Gly Phe
                1160                1165                1170

 Val Ile Val Thr Phe Gln Glu Gln Gly Glu Lys Glu Tyr Lys Asn
                1175                1180                1185

 Cys Glu Leu Asp Lys Asn Gln Arg Gln Cys Val Glu Tyr Ala Leu
                1190                1195                1200

 Lys Ala Arg Pro Leu Arg Arg Tyr Ile Pro Lys Asn Pro Tyr Gln
                1205                1210                1215

 Tyr Lys Phe Trp Tyr Val Val Asn Ser Ser Pro Phe Glu Tyr Met
                1220                1225                1230

 Met Phe Val Leu Ile Met Leu Asn Thr Leu Cys Leu Ala Met Gln
                1235                1240                1245

 His Tyr Glu Gln Ser Lys Met Phe Asn Asp Ala Met Asp Ile Leu
                1250                1255                1260

 Asn Met Val Phe Thr Gly Val Phe Thr Val Glu Met Val Leu Lys
                1265                1270                1275

 Val Ile Ala Phe Lys Pro Lys Gly Tyr Phe Ser Asp Ala Trp Asn
                1280                1285                1290

 Thr Phe Asp Ser Leu Ile Val Ile Gly Ser Ile Ile Asp Val Ala
                1295                1300                1305

 Leu Ser Glu Ala Asp Pro Thr Glu Ser Glu Asn Val Pro Val Pro
                1310                1315                1320

 Thr Ala Thr Pro Gly Asn Ser Glu Glu Ser Asn Arg Ile Ser Ile
                1325                1330                1335

 Thr Phe Phe Arg Leu Phe Arg Val Met Arg Leu Val Lys Leu Leu
                1340                1345                1350

 Ser Arg Gly Glu Gly Ile Arg Thr Leu Leu Trp Thr Phe Ile Lys
                1355                1360                1365

 Ser Phe Gln Ala Leu Pro Tyr Val Ala Leu Leu Ile Ala Met Leu
                1370                1375                1380

 Phe Phe Ile Tyr Ala Val Ile Gly Met Gln Met Phe Gly Lys Val
                1385                1390                1395

 Ala Met Arg Asp Asn Asn Gln Ile Asn Arg Asn Asn Asn Phe Gln
                1400                1405                1410

 Thr Phe Pro Gln Ala Val Leu Leu Leu Phe Arg Cys Ala Thr Gly
                1415                1420                1425

 Glu Ala Trp Gln Glu Ile Met Leu Ala Cys Leu Pro Gly Lys Leu
                1430                1435                1440

 Cys Asp Pro Glu Ser Asp Tyr Asn Pro Gly Glu Glu Tyr Thr Cys
                1445                1450                1455

 Gly Ser Asn Phe Ala Ile Val Tyr Phe Ile Ser Phe Tyr Met Leu
                1460                1465                1470

 Cys Ala Phe Leu Ile Ile Asn Leu Phe Val Ala Val Ile Met Asp
                1475                1480                1485

 Asn Phe Asp Tyr Leu Thr Arg Asp Trp Ser Ile Leu Gly Pro His
                1490                1495                1500

 His Leu Asp Glu Phe Lys Arg Ile Trp Ser Glu Tyr Asp Pro Glu
                1505                1510                1515

 Ala Lys Gly Arg Ile Lys His Leu Asp Val Val Thr Leu Leu Arg
                1520                1525                1530

 Arg Ile Gln Pro Pro Leu Gly Phe Gly Lys Leu Cys Pro His Arg
                1535                1540                1545

 Val Ala Cys Lys Arg Leu Val Ala Met Asn Met Pro Leu Asn Ser
                1550                1555                1560

 Asp Gly Thr Val Met Phe Asn Ala Thr Leu Phe Ala Leu Val Arg
                1565                1570                1575

 Thr Ala Leu Lys Ile Lys Thr Glu Gly Asn Leu Glu Gln Ala Asn
                1580                1585                1590

 Glu Glu Leu Arg Ala Val Ile Lys Lys Ile Trp Lys Lys Thr Ser
                1595                1600                1605

 Met Lys Leu Leu Asp Gln Val Val Pro Pro Ala Gly Asp Asp Glu
                1610                1615                1620

 Val Thr Val Gly Lys Phe Tyr Ala Thr Phe Leu Ile Gln Asp Tyr
                1625                1630                1635

 Phe Arg Lys Phe Lys Lys Arg Lys Glu Gln Gly Leu Val Gly Lys
                1640                1645                1650

 Tyr Pro Ala Lys Asn Thr Thr Ile Ala Leu Gln Ala Gly Leu Arg
                1655                1660                1665

 Thr Leu His Asp Ile Gly Pro Glu Ile Arg Arg Ala Ile Ser Cys
                1670                1675                1680

 Asp Leu Gln Asp Asp Glu Pro Glu Glu Thr Lys Arg Glu Glu Glu
                1685                1690                1695

 Asp Asp Val Phe Lys Arg Asn Gly Ala Leu Leu Gly Asn His Val
                1700                1705                1710

 Asn His Val Asn Ser Asp Arg Arg Asp Ser Leu Gln Gln Thr Asn
                1715                1720                1725

 Thr Thr His Arg Pro Leu His Val Gln Arg Pro Ser Ile Pro Pro
                1730                1735                1740

 Ala Ser Asp Thr Glu Lys Pro Leu Phe Pro Pro Ala Gly Asn Ser
                1745                1750                1755

 Val Cys His Asn His His Asn His Asn Ser Ile Gly Lys Gln Val
                1760                1765                1770

 Pro Thr Ser Thr Asn Ala Asn Leu Asn Asn Ala Asn Met Ser Lys
                1775                1780                1785

 Ala Ala His Gly Lys Arg Pro Ser Ile Gly Asn Leu Glu His Val
                1790                1795                1800

 Ser Glu Asn Gly His His Ser Ser His Lys His Asp Arg Glu Pro
                1805                1810                1815

 Gln Arg Arg Ser Ser Val Lys Arg Thr Arg Tyr Tyr Glu Thr Tyr
                1820                1825                1830

 Ile Arg Ser Asp Ser Gly Asp Glu Gln Leu Pro Thr Ile Cys Arg
                1835                1840                1845

 Glu Asp Pro Glu Ile His Gly Tyr Phe Arg Asp Pro His Cys Leu
                1850                1855                1860

 Gly Glu Gln Glu Tyr Phe Ser Ser Glu Glu Cys Tyr Glu Asp Asp
                1865                1870                1875

 Ser Ser Pro Thr Trp Ser Arg Gln Asn Tyr Gly Tyr Tyr Ser Arg
                1880                1885                1890

 Tyr Pro Gly Arg Asn Ile Asp Ser Glu Arg Pro Arg Gly Tyr His
                1895                1900                1905

 His Pro Gln Gly Phe Leu Glu Asp Asp Asp Ser Pro Val Cys Tyr
                1910                1915                1920

 Asp Ser Arg Arg Ser Pro Arg Arg Arg Leu Leu Pro Pro Thr Pro
                1925                1930                1935

 Ala Ser His Arg Arg Ser Ser Phe Asn Phe Glu Cys Leu Arg Arg
                1940                1945                1950

 Gln Ser Ser Gln Glu Glu Val Pro Ser Ser Pro Ile Phe Pro His
                1955                1960                1965

 Arg Thr Ala Leu Pro Leu His Leu Met Gln Gln Gln Ile Met Ala
                1970                1975                1980

 Val Ala Gly Leu Asp Ser Ser Lys Ala Gln Lys Tyr Ser Pro Ser
                1985                1990                1995

 His Ser Thr Arg Ser
                2000

<210> 1711
<211> 2289
<212> DNA
<213> Homo sapien

<400> 1711
 gtctcggcca tgacacacat ttgacatgcc ctccctcaac ctacttatag 50

 actatttttc ttgctctgca gcatggacca aagagaaatt ctgcagaagt 100

 tcctggatga ggcccaaagc aagaaaatta ctaaagagga gtttgccaat 150

 gaatttctga agctgaaaag gcaatctacc aagtacaagg cagacaaaac 200

 ctatcctaca actgtggctg agaatgccaa gaatatcaag aaaaacagat 250

 ataaggatat tttgccctat gattatagcc gggtagaact atccctgata 300

 acctctgatg aggattccag ctacatcaat gccaacttca ttaagggagt 350

 ttatggaccc aaggcttata ttgccaccca gggtccttta tctacaaccc 400

 tcctggactt ctggaggatg atttgggaat atagtgtcct tatcattgtt 450

 atggcatgca tggagtatga aatgggaaag aaaaagtgtg agcgctactg 500

 ggctgagcca ggagagatgc agctggaatt tggccctttc tctgtatcct 550

 gtgaagctga aaaaaggaaa tctgattata taatcaggac tctaaaagtt 600

 aagttcaata gtgaaactcg aactatctac cagtttcatt acaagaattg 650

 gccagaccat gatgtacctt catctataga ccctattctt gagctcatct 700

 gggatgtacg ttgttaccaa gaggatgaca gtgttcccat atgcattcac 750

 tgcagtgctg gctgtggaag gactggtgtt atttgtgcta ttgattatac 800

 atggatgttg ctaaaagatg ggataattcc tgagaacttc agtgttttca 850

 gtttgatccg ggaaatgcgg acacagaggc cttcattagt tcaaacgcag 900

 gaacaatatg aactggtcta caatgctgta ttagaactat ttaagagaca 950

 gatggatgtt atcagagata aacattctgg aacagagagt caagcaaagc 1000

 attgtattcc tgagaaaaat cacactctcc aagcagactc ttattctcct 1050

 aatttaccaa aaagtaccac aaaagcagca aaaatgatga accaacaaag 1100

 gacaaaaatg gaaatcaaag aatcttcttc ctttgacttt aggacttctg 1150

 aaataagtgc aaaagaagag ctagttttgc accctgctaa atcaagcact 1200

 tcttttgact ttctggagct aaattacagt tttgacaaaa atgctgacac 1250

 aaccatgaaa tggcagacaa aggcatttcc aatagttggg gagcctcttc 1300

 agaagcatca aagtttggat ttgggctctc ttttgtttga gggatgttct 1350

 aattctaaac ctgtaaatgc agcaggaaga tattttaatt caaaggtgcc 1400

 aataacacgg accaaatcaa ctccttttga attgatacag cagagagaaa 1450

 ccaaggaggt ggacagcaag gaaaactttt cttatttgga atctcaacca 1500

 catgattctt gttttgtaga gatgcaggct caaaaagtaa tgcatgtttc 1550

 ttcagcagaa ctgaattatt cactgccata tgactctaaa caccaaatac 1600

 gtaatgcctc taatgtaaag caccatgact ctagtgctct tggtgtatat 1650

 tcttacatac ctttagtgga aaatccttat ttttcatcat ggcctccaag 1700

 tggtaccagt tctaagatgt ctcttgattt acctgagaag caagatggaa 1750

 ctgtttttcc ttcttctctg ttgccaacat cctctacatc cctcttctct 1800

 tattacaatt cacatgattc tttatcactg aattctccaa ccaatatttc 1850

 ctcactattg aaccaggagt cagctgtact agcaactgct ccaaggatag 1900

 atgatgaaat cccccctcca cttcctgtac ggacacctga atcatttatt 1950

 gtggttgagg aagctggaga attctcacca aatgttccca aatccttatc 2000

 ctcagctgtg aaggtaaaaa ttggaacatc actggaatgg ggtggaacat 2050

 ctgaaccaaa gaaatttgat gactctgtga tacttagacc aagcaagagt 2100

 gtaaaactcc gaagtcctaa atcaggtaaa aatttctctt ggctttagat 2150

 gacatttagc cctaagattg gaagaatggt tcgttaagtt tagagtaatt 2200

 cacttcagga agttacttgg ttcccataat agcttccagt attcattgat 2250

 ttatttctgg ctttcccaga ctagaaattt tgtaaagag 2289

<210> 1712
<211> 691
<212> PRT
<213> Homo sapien

<400> 1712
 Met Asp Gln Arg Glu Ile Leu Gln Lys Phe Leu Asp Glu Ala Gln
   1               5                  10                  15

 Ser Lys Lys Ile Thr Lys Glu Glu Phe Ala Asn Glu Phe Leu Lys
                  20                  25                  30

 Leu Lys Arg Gln Ser Thr Lys Tyr Lys Ala Asp Lys Thr Tyr Pro
                  35                  40                  45

 Thr Thr Val Ala Glu Asn Ala Lys Asn Ile Lys Lys Asn Arg Tyr
                  50                  55                  60

 Lys Asp Ile Leu Pro Tyr Asp Tyr Ser Arg Val Glu Leu Ser Leu
                  65                  70                  75

 Ile Thr Ser Asp Glu Asp Ser Ser Tyr Ile Asn Ala Asn Phe Ile
                  80                  85                  90

 Lys Gly Val Tyr Gly Pro Lys Ala Tyr Ile Ala Thr Gln Gly Pro
                  95                 100                 105

 Leu Ser Thr Thr Leu Leu Asp Phe Trp Arg Met Ile Trp Glu Tyr
                 110                 115                 120

 Ser Val Leu Ile Ile Val Met Ala Cys Met Glu Tyr Glu Met Gly
                 125                 130                 135

 Lys Lys Lys Cys Glu Arg Tyr Trp Ala Glu Pro Gly Glu Met Gln
                 140                 145                 150

 Leu Glu Phe Gly Pro Phe Ser Val Ser Cys Glu Ala Glu Lys Arg
                 155                 160                 165

 Lys Ser Asp Tyr Ile Ile Arg Thr Leu Lys Val Lys Phe Asn Ser
                 170                 175                 180

 Glu Thr Arg Thr Ile Tyr Gln Phe His Tyr Lys Asn Trp Pro Asp
                 185                 190                 195

 His Asp Val Pro Ser Ser Ile Asp Pro Ile Leu Glu Leu Ile Trp
                 200                 205                 210

 Asp Val Arg Cys Tyr Gln Glu Asp Asp Ser Val Pro Ile Cys Ile
                 215                 220                 225

 His Cys Ser Ala Gly Cys Gly Arg Thr Gly Val Ile Cys Ala Ile
                 230                 235                 240

 Asp Tyr Thr Trp Met Leu Leu Lys Asp Gly Ile Ile Pro Glu Asn
                 245                 250                 255

 Phe Ser Val Phe Ser Leu Ile Arg Glu Met Arg Thr Gln Arg Pro
                 260                 265                 270

 Ser Leu Val Gln Thr Gln Glu Gln Tyr Glu Leu Val Tyr Asn Ala
                 275                 280                 285

 Val Leu Glu Leu Phe Lys Arg Gln Met Asp Val Ile Arg Asp Lys
                 290                 295                 300

 His Ser Gly Thr Glu Ser Gln Ala Lys His Cys Ile Pro Glu Lys
                 305                 310                 315

 Asn His Thr Leu Gln Ala Asp Ser Tyr Ser Pro Asn Leu Pro Lys
                 320                 325                 330

 Ser Thr Thr Lys Ala Ala Lys Met Met Asn Gln Gln Arg Thr Lys
                 335                 340                 345

 Met Glu Ile Lys Glu Ser Ser Ser Phe Asp Phe Arg Thr Ser Glu
                 350                 355                 360

 Ile Ser Ala Lys Glu Glu Leu Val Leu His Pro Ala Lys Ser Ser
                 365                 370                 375

 Thr Ser Phe Asp Phe Leu Glu Leu Asn Tyr Ser Phe Asp Lys Asn
                 380                 385                 390

 Ala Asp Thr Thr Met Lys Trp Gln Thr Lys Ala Phe Pro Ile Val
                 395                 400                 405

 Gly Glu Pro Leu Gln Lys His Gln Ser Leu Asp Leu Gly Ser Leu
                 410                 415                 420

 Leu Phe Glu Gly Cys Ser Asn Ser Lys Pro Val Asn Ala Ala Gly
                 425                 430                 435

 Arg Tyr Phe Asn Ser Lys Val Pro Ile Thr Arg Thr Lys Ser Thr
                 440                 445                 450

 Pro Phe Glu Leu Ile Gln Gln Arg Glu Thr Lys Glu Val Asp Ser
                 455                 460                 465

 Lys Glu Asn Phe Ser Tyr Leu Glu Ser Gln Pro His Asp Ser Cys
                 470                 475                 480

 Phe Val Glu Met Gln Ala Gln Lys Val Met His Val Ser Ser Ala
                 485                 490                 495

 Glu Leu Asn Tyr Ser Leu Pro Tyr Asp Ser Lys His Gln Ile Arg
                 500                 505                 510

 Asn Ala Ser Asn Val Lys His His Asp Ser Ser Ala Leu Gly Val
                 515                 520                 525

 Tyr Ser Tyr Ile Pro Leu Val Glu Asn Pro Tyr Phe Ser Ser Trp
                 530                 535                 540

 Pro Pro Ser Gly Thr Ser Ser Lys Met Ser Leu Asp Leu Pro Glu
                 545                 550                 555

 Lys Gln Asp Gly Thr Val Phe Pro Ser Ser Leu Leu Pro Thr Ser
                 560                 565                 570

 Ser Thr Ser Leu Phe Ser Tyr Tyr Asn Ser His Asp Ser Leu Ser
                 575                 580                 585

 Leu Asn Ser Pro Thr Asn Ile Ser Ser Leu Leu Asn Gln Glu Ser
                 590                 595                 600

 Ala Val Leu Ala Thr Ala Pro Arg Ile Asp Asp Glu Ile Pro Pro
                 605                 610                 615

 Pro Leu Pro Val Arg Thr Pro Glu Ser Phe Ile Val Val Glu Glu
                 620                 625                 630

 Ala Gly Glu Phe Ser Pro Asn Val Pro Lys Ser Leu Ser Ser Ala
                 635                 640                 645

 Val Lys Val Lys Ile Gly Thr Ser Leu Glu Trp Gly Gly Thr Ser
                 650                 655                 660

 Glu Pro Lys Lys Phe Asp Asp Ser Val Ile Leu Arg Pro Ser Lys
                 665                 670                 675

 Ser Val Lys Leu Arg Ser Pro Lys Ser Gly Lys Asn Phe Ser Trp
                 680                 685                 690

 Leu


<210> 1713
<211> 1962
<212> DNA
<213> Homo sapien

<400> 1713
 gttttgcctg ctagcatctc cctgtaactc tcccaatctt gaggagtgat 50

 ccctgtccca gcccctggaa aggggcagga acgacaaact caaagtccag 100

 gatgttcacc atgacaagag ccatggaaga ggctcttttt cagcacttca 150

 tgcaccagaa gctggggatc gcctatgcca tacacaagcc atttcccttc 200

 tttgaaggcc tcctagacaa ctccatcatc actaagagaa tgtacatgga 250

 atctctggaa gcctgtagaa atttgatccc tgtatccaga gtggtgcaca 300

 acattctcac ccaactggag aggactttta acctgtctct tctggtgaca 350

 ttgttcagtc aaattaacct gcgtgaatat cccaatctgg tgacgattta 400

 cagaagcttc aaacgtgttg gtgcttccta tgaacggcag agcagagaca 450

 caccaatcct acttgaagcc ccaactggcc tagcagaagg aagctccctc 500

 cataccccac tggcgctgcc cccaccacaa ccccctcaac caagctgttc 550

 accctgtgcg ccaagagtca gtgagcctgg aacatcctcc cagcaaagcg 600

 atgagatcct gagtgagtcg cccagcccat ctgaccctgt cctgcctctc 650

 cctgcactca tccaggaagg aagaagcact tcagtgacca atgacaagtt 700

 aacatccaaa atgaatgcgg aagaagactc agaagagatg cccagcctcc 750

 tcactagcac tgtgcaagtg gccagtgaca acctgatccc ccaaataaga 800

 gataaagaag accctcaaga gatgccccac tctcccttgg gctctatgcc 850

 agagataaga gataattctc cagaaccaaa tgacccagaa gagccccagg 900

 aggtgtccag cacaccttca gacaagaaag gaaagaaaag aaaaagatgt 950

 atctggtcaa ctccaaaaag gagacataag aaaaaaagcc tcccaagagg 1000

 gacagcctca tctagacacg gaatccaaaa gaagctcaaa agggtggatc 1050

 aggttcctca aaagaaagat gactcaactt gtaactccac ggtagagaca 1100

 agggcccaaa aggcgagaac tgaatgtgcc cgaaagtcga gatcagagga 1150

 gatcattgat ggcacttcag aaatgaatga aggaaagagg tcccagaaga 1200

 cgcctagtac accacgaagg gtcacacaag gggcagcctc acctgggcat 1250

 ggcatccaag agaagctcca agtggtggat aaggtgactc aaaggaaaga 1300

 cgactcaacc tggaactcag aggtcatgat gagggtccaa aaggcaagaa 1350

 ctaaatgtgc ccgaaagtcc agatcgaaag aaaagaaaaa ggagaaagat 1400

 atctgttcaa gctcaaaaag gagatttcag aaaaatattc accgaagagg 1450

 aaaacccaaa agtgacactg tggattttca ctgttctaag ctccccgtga 1500

 cctgtggtga ggcgaaaggg attttatata agaagaaaat gaaacacgga 1550

 tcctcagtga agtgcattcg gaatgaggat ggaacttggt taacaccaaa 1600

 tgaatttgaa gtcgaaggaa aaggaaggaa cgcaaagaac tggaaacgga 1650

 atatacgttg tgaaggaatg accctaggag agctgctgaa gagtggactt 1700

 ttgctctgtc ctccaagaat aaatctcaag agagagttaa atagcaagtg 1750

 aatttctact accctctcag tcaccatgtt gcagactttc cctgtctgga 1800

 ggctcacctt agagcttctg agtttccaag ctctgagtca cctccacatt 1850

 tgggcatggc atcttcaaaa caattaattt gcatagttaa tttgggatgg 1900

 ggaagcaaat gactctaaaa taaaaattaa atgaaaaagc tcaaaaaaaa 1950

 aaaaaaaaaa aa 1962

<210> 1714
<211> 549
<212> PRT
<213> Homo sapien

<400> 1714
 Met Phe Thr Met Thr Arg Ala Met Glu Glu Ala Leu Phe Gln His
   1               5                  10                  15

 Phe Met His Gln Lys Leu Gly Ile Ala Tyr Ala Ile His Lys Pro
                  20                  25                  30

 Phe Pro Phe Phe Glu Gly Leu Leu Asp Asn Ser Ile Ile Thr Lys
                  35                  40                  45

 Arg Met Tyr Met Glu Ser Leu Glu Ala Cys Arg Asn Leu Ile Pro
                  50                  55                  60

 Val Ser Arg Val Val His Asn Ile Leu Thr Gln Leu Glu Arg Thr
                  65                  70                  75

 Phe Asn Leu Ser Leu Leu Val Thr Leu Phe Ser Gln Ile Asn Leu
                  80                  85                  90

 Arg Glu Tyr Pro Asn Leu Val Thr Ile Tyr Arg Ser Phe Lys Arg
                  95                 100                 105

 Val Gly Ala Ser Tyr Glu Arg Gln Ser Arg Asp Thr Pro Ile Leu
                 110                 115                 120

 Leu Glu Ala Pro Thr Gly Leu Ala Glu Gly Ser Ser Leu His Thr
                 125                 130                 135

 Pro Leu Ala Leu Pro Pro Pro Gln Pro Pro Gln Pro Ser Cys Ser
                 140                 145                 150

 Pro Cys Ala Pro Arg Val Ser Glu Pro Gly Thr Ser Ser Gln Gln
                 155                 160                 165

 Ser Asp Glu Ile Leu Ser Glu Ser Pro Ser Pro Ser Asp Pro Val
                 170                 175                 180

 Leu Pro Leu Pro Ala Leu Ile Gln Glu Gly Arg Ser Thr Ser Val
                 185                 190                 195

 Thr Asn Asp Lys Leu Thr Ser Lys Met Asn Ala Glu Glu Asp Ser
                 200                 205                 210

 Glu Glu Met Pro Ser Leu Leu Thr Ser Thr Val Gln Val Ala Ser
                 215                 220                 225

 Asp Asn Leu Ile Pro Gln Ile Arg Asp Lys Glu Asp Pro Gln Glu
                 230                 235                 240

 Met Pro His Ser Pro Leu Gly Ser Met Pro Glu Ile Arg Asp Asn
                 245                 250                 255

 Ser Pro Glu Pro Asn Asp Pro Glu Glu Pro Gln Glu Val Ser Ser
                 260                 265                 270

 Thr Pro Ser Asp Lys Lys Gly Lys Lys Arg Lys Arg Cys Ile Trp
                 275                 280                 285

 Ser Thr Pro Lys Arg Arg His Lys Lys Lys Ser Leu Pro Arg Gly
                 290                 295                 300

 Thr Ala Ser Ser Arg His Gly Ile Gln Lys Lys Leu Lys Arg Val
                 305                 310                 315

 Asp Gln Val Pro Gln Lys Lys Asp Asp Ser Thr Cys Asn Ser Thr
                 320                 325                 330

 Val Glu Thr Arg Ala Gln Lys Ala Arg Thr Glu Cys Ala Arg Lys
                 335                 340                 345

 Ser Arg Ser Glu Glu Ile Ile Asp Gly Thr Ser Glu Met Asn Glu
                 350                 355                 360

 Gly Lys Arg Ser Gln Lys Thr Pro Ser Thr Pro Arg Arg Val Thr
                 365                 370                 375

 Gln Gly Ala Ala Ser Pro Gly His Gly Ile Gln Glu Lys Leu Gln
                 380                 385                 390

 Val Val Asp Lys Val Thr Gln Arg Lys Asp Asp Ser Thr Trp Asn
                 395                 400                 405

 Ser Glu Val Met Met Arg Val Gln Lys Ala Arg Thr Lys Cys Ala
                 410                 415                 420

 Arg Lys Ser Arg Ser Lys Glu Lys Lys Lys Glu Lys Asp Ile Cys
                 425                 430                 435

 Ser Ser Ser Lys Arg Arg Phe Gln Lys Asn Ile His Arg Arg Gly
                 440                 445                 450

 Lys Pro Lys Ser Asp Thr Val Asp Phe His Cys Ser Lys Leu Pro
                 455                 460                 465

 Val Thr Cys Gly Glu Ala Lys Gly Ile Leu Tyr Lys Lys Lys Met
                 470                 475                 480

 Lys His Gly Ser Ser Val Lys Cys Ile Arg Asn Glu Asp Gly Thr
                 485                 490                 495

 Trp Leu Thr Pro Asn Glu Phe Glu Val Glu Gly Lys Gly Arg Asn
                 500                 505                 510

 Ala Lys Asn Trp Lys Arg Asn Ile Arg Cys Glu Gly Met Thr Leu
                 515                 520                 525

 Gly Glu Leu Leu Lys Ser Gly Leu Leu Leu Cys Pro Pro Arg Ile
                 530                 535                 540

 Asn Leu Lys Arg Glu Leu Asn Ser Lys
                 545

<210> 1715
<211> 1010
<212> DNA
<213> Homo sapien

<400> 1715
 agttctgtcc ttgcattggt gcgcctcagg ccaggctgca ctgctgggac 50

 ctgggccatg tctccccacc ccaccgccct cctgggccta gtgctctgcc 100

 tggcccagac catccacacg caggaggaag atctgcccag accctccatc 150

 tcggctgagc caggcaccgt gatccccctg gggagccatg tgactttcgt 200

 gtgccggggc ccggttgggg ttcaaacatt ccgcctggag agggagagta 250

 gatccacata caatgatact gaagatgtgt ctcaagctag tccatctgag 300

 tcagaggcca gattccgcat tgactcagta agtgaaggaa atgccgggcc 350

 ttatcgctgc atctattata agccccctaa atggtctgag cagagtgact 400

 acctggagct gctggtgaaa gaaacctctg gaggcccgga ctccccggac 450

 acagagcccg gctcctcagc tggacccacg cagaggccgt cggacaacag 500

 tcacaatgag catgcacctg cttcccaagg cctgaaagct gagcatctgt 550

 atattctcat cggggtctca gtggtcttcc tcttctgtct cctcctcctg 600

 gtcctcttct gcctccatcg ccagaatcag ataaagcagg ggccccccag 650

 aagcaaggac gaggagcaga agccacagca gaggtgaggc ccctgggaat 700

 gactcctgga cctccaccca gtcctcggcc gccaggctgc ccctgaggtt 750

 cacttttatt tttcctctta ggcctgacct ggctgttgat gttctagaga 800

 ggacagcaga caaggccaca gtcaatggac ttcctgagaa ggacagagag 850

 acggacacct cggccctggc tgcagggagt tcccaggagg tgacgtatgc 900

 tcagctggac cactgggccc tcacacagag gacagcccgg gctgtgtccc 950

 cacagtccac aaagcccatg gccgagtcca tcacgtatgc agccgttgcc 1000

 agacactgac 1010

<210> 1716
<211> 209
<212> PRT
<213> Homo sapien

<400> 1716
 Met Ser Pro His Pro Thr Ala Leu Leu Gly Leu Val Leu Cys Leu
   1               5                  10                  15

 Ala Gln Thr Ile His Thr Gln Glu Glu Asp Leu Pro Arg Pro Ser
                  20                  25                  30

 Ile Ser Ala Glu Pro Gly Thr Val Ile Pro Leu Gly Ser His Val
                  35                  40                  45

 Thr Phe Val Cys Arg Gly Pro Val Gly Val Gln Thr Phe Arg Leu
                  50                  55                  60

 Glu Arg Glu Ser Arg Ser Thr Tyr Asn Asp Thr Glu Asp Val Ser
                  65                  70                  75

 Gln Ala Ser Pro Ser Glu Ser Glu Ala Arg Phe Arg Ile Asp Ser
                  80                  85                  90

 Val Ser Glu Gly Asn Ala Gly Pro Tyr Arg Cys Ile Tyr Tyr Lys
                  95                 100                 105

 Pro Pro Lys Trp Ser Glu Gln Ser Asp Tyr Leu Glu Leu Leu Val
                 110                 115                 120

 Lys Glu Thr Ser Gly Gly Pro Asp Ser Pro Asp Thr Glu Pro Gly
                 125                 130                 135

 Ser Ser Ala Gly Pro Thr Gln Arg Pro Ser Asp Asn Ser His Asn
                 140                 145                 150

 Glu His Ala Pro Ala Ser Gln Gly Leu Lys Ala Glu His Leu Tyr
                 155                 160                 165

 Ile Leu Ile Gly Val Ser Val Val Phe Leu Phe Cys Leu Leu Leu
                 170                 175                 180

 Leu Val Leu Phe Cys Leu His Arg Gln Asn Gln Ile Lys Gln Gly
                 185                 190                 195

 Pro Pro Arg Ser Lys Asp Glu Glu Gln Lys Pro Gln Gln Arg
                 200                 205

<210> 1717
<211> 9078
<212> DNA
<213> Homo sapien

<400> 1717
 ctgaactagt tgccagtgat cttgaaacgt gacagtaacc aagagataaa 50

 taggtgacaa tgacaggaaa attagatgta gtaaaagaga gtgtttgaga 100

 gcagaagcta tggcaactaa agactggatt tgaatccttc ctagcttggt 150

 gacatgagca aattacttga tttaagtgag cattttccca tctgtacagt 200

 ggagataacg ataattgtgc ctgctaagaa gaattgctgt gaagattagt 250

 gaaataatgc atgtaaaaca tttggtacag tatgtgacac atagtacaaa 300

 tagtttgcta ggaagattgt tattattctt cacttgtgat attgtgaagt 350

 tttcatacag caaattggac atcatgagat ggattgatta aataaataga 400

 tttgaacttc aaggactggt agtgttcttg ctttggaaag aagaaacttg 450

 gtttatccta ataatagtag gataataatg gtgaagtgat aggtacaagt 500

 aatagtgttt atgatgcgct ggtgatgata ggaaaagaaa gccattatat 550

 gggcaagagc tagaagtaat aaaatggtgc atttttcagt gatgtttggc 600

 ctatgtagct attctctgat aactataaaa atccttatta ttgaagattc 650

 ttcaggaaaa aaaaaccctt agtctgaaac tttagcacca atcccccttg 700

 ccccccattg aaatacgtat ttttaaaaca tggcttttga taatgtgagg 750

 gttttttcct ttttgcgatt tagcagtgct gattgtgtat tgcagtagtt 800

 gtgagagcat tagaagcagc agtcgatagg aggatggaag gtctggatgc 850

 cgccttgggg agttaggaga ttggcagact taccctgtac cactctagcc 900

 ctactccttt gcccaagaca gaaacacact gagatggata ggagaatatg 950

 agcagttgat aggaaagttc tcagtggagt caggatttag gttaggccag 1000

 gagattgaga atataacagt ttgtgtatga tgaaatggca tatttcacag 1050

 aatgcagtaa aagcaggtag ggtacaagtg cagcaacagg aagatgtctt 1100

 ttcttcattc agcaaacact tatttgagag cttaccatgt gctaggcaca 1150

 tacaaagata aataagatgc ccttgatgat cctctattta aaggagacat 1200

 gtaaacaggt taacttagag tagagatggt gaatatgtga acctgaggaa 1250

 aggaagaaat agattaaatt atctggagag agaggaaaag tcagcagaat 1300

 ggggacgaga atctttcgga gctcagtgtt ctgataggag ttatttcctt 1350

 gggcataggt tccaagtatt tttctaatat accatagaag ccaggaaaac 1400

 tttcttctgt tatctcaaat gatttaatta ctgacttgag tttgtgttgt 1450

 ctccttagac ttgtgcacca tggacaattt tgctgaggga gatttcactg 1500

 tggcggatta tgccttgtta gaagattgcc ctcacgtgga tgattgtgtc 1550

 tttgctgctg aatttatgag caatgattat gttcgtgtga ctcagcttta 1600

 ctgtgatggg gtgggtgtgc aatataaaga ttatatccaa agtgagagga 1650

 atttggaatt tgacatctgc agtatatggt gtagtaaacc aatttctgtc 1700

 ctgcaagatt attgcgatgc cattaaaata aacatcttct ggccacttct 1750

 gtttcaacat caaaacagtt ccgtaatatc acgattgcat ccctgtgtgg 1800

 acgccaacaa ttcacgtgct tctgagataa atttgaagaa actacaacat 1850

 cttgagttga tggaagatat tgtggatttg gcaaagaaag ttgctaatga 1900

 ttcattcctt attggaggct tattgagaat tggttgtaaa atagaaaata 1950

 aaatcttggc aatggaagaa gctctgaatt ggataaaata tgcaggcgat 2000

 gtaacaattc taactaaatt aggatcaatt gacaattgtt ggcctatgtt 2050

 aagtattttc tttactgaat acaagtacca cataactaaa attgtaatgg 2100

 aagactgcaa tttgcttgaa gaacttaaaa ctcaaagttg tatggattgt 2150

 atagaggaag gagaactaat gaaaatgaaa ggaaatgaag agttttccaa 2200

 agaaagattt gatatagcta ttatctatta caccagagcc attgaatata 2250

 gacctgaaaa ctaccttctt tatggtaacc gagctctttg ttttcttcgt 2300

 actggacagt ttagaaatgc actcggtgat ggaaagagag ccactattct 2350

 gaagaacact tggccaaagg gtcattatcg ttattgtgat gctctttcta 2400

 tgctggggga atatgactgg gccctgcaag caaacataaa agctcaaaaa 2450

 ctctgtaaaa atgaccctga gggaatcaag gatctaattc agcagcatgt 2500

 aaagttacaa aaacaaatag aagacctaca aggtcgaaca gcaaataagg 2550

 atccaattaa agccttttat gaaaacaggg cctacacacc taggagttta 2600

 tcagcaccta tatttactac ttcacttaac tttgtggaga aggaaagaga 2650

 tttcagaaaa attaatcacg aaatggccaa cggtggtaat cagaatctaa 2700

 aggtggcgga tgaggcgttg aaggtagatg attgtgactg tcatcctgaa 2750

 ttttcaccac catcaagtca gcctccaaaa cataaaggaa aacaaaaatc 2800

 tcgaaacaat gaatcagaaa agttcagttc tagttcacca ttgactttac 2850

 cagcagattt gaagaacatc ttggagaaac agttttctaa atcttccaga 2900

 gctgcacacc aggattttgc taatataatg aaaatgctga gaagcttaat 2950

 tcaagatggc tatatggcct tattggagca gcgttgccgc agcgctgcac 3000

 aggcctttac agagttgctg aacggtttag atcctcaaaa aataaagcaa 3050

 ttgaacctgg ccatgattaa ctatgttttg gtcgtctatg gacttgccat 3100

 ttctctcctt ggaataggac agcctgagga attatctgaa gccgaaaacc 3150

 agtttaagag gattattgaa cactacccca gtgagggcct tgattgcttg 3200

 gcctactgtg gaattggaaa agtgtatttg aaaaaaaaca gatttctaga 3250

 agctctcaat cactttgaga aagcaagaac cttgatttat cgtcttcctg 3300

 gagtgttaac ttggcccacg agtaatgtga ttattgaaga gtctcagcca 3350

 caaaaaataa agatgctgtt agagaaattt gttgaagaat gcaagttccc 3400

 tccagtgcca gatgccattt gttgctatca gaagtgccat ggatattcta 3450

 agatccagat atacataact gatccagact ttaagggttt tatacgcatc 3500

 agctgttgcc agtactgtaa aatagaattt cacatgaatt gctggaagaa 3550

 gttaaaaact acaaccttta atgataaaat tgacaaggat tttctacaag 3600

 gaatatgtct tacccctgac tgtgaaggtg tcatttctaa gattatcatc 3650

 ttcagcagtg gtggtgaagt taaatgtgaa tttgaacaca aggtcataaa 3700

 agaaaaggtt cctccaagac ctattctgaa acagaaatgt tctagcctag 3750

 agaaactaag actgaaagaa gacaaaaaat tgaagagaaa gatccaaaaa 3800

 aaagaagcaa aaaagttagc acaagaaaga atggaggagg acttaagaga 3850

 aagtaatcca cccaaaaatg aagagcagaa agaaactgta gacaatgttc 3900

 agcgttgtca gttccttgat gacagaattc tacagtgtat aaagcagtat 3950

 gctgacaaga ttaaatccgg catacagaat acagccatgc ttctcaaaga 4000

 attgctttct tggaaagttt tgagcacaga agactataca acctgttttt 4050

 ctagcagaaa ttttctaaat gaagcagtgg actatgttat tcgccacttg 4100

 attcaagaaa ataacagagt aaagacaaga atatttctgc atgttttgag 4150

 tgagcttaaa gaagtggagc ccaaattagc cgcctggatc caaaaactta 4200

 atagctttgg cttagatgcc acaggaactt tcttttctcg ttatggagca 4250

 tctcttaaac tgcttgattt tagtatcatg actttcctct ggaatgagaa 4300

 atatggtcac aaactagact ctatagaagg aaagcaactt gattatttct 4350

 ctgagccagc atcattgaag gaagcccgtt gtttaatatg gctgctagaa 4400

 gaacacagag acaagttccc agcattgcat agtgctttag atgaattctt 4450

 tgatataatg gacagccgct gtactgtgtt aaggaaacaa gatagtggtg 4500

 aagcaccgtt tagttcaacc aaggtgaaaa acaaaagcaa gaaaaagaag 4550

 ccaaaggatt caaagcctat gttagttggg tctggaacaa cttcagtaac 4600

 ttcaaataat gagatcatca cttcaagtga agaccatagc aatcgaaatt 4650

 cagattctgc aggcccattt gcagtgcctg accatcttcg gcaagatgta 4700

 gaagaattcg aagctctcta tgaccaacac agtaacgaat atgttgtccg 4750

 caataagaag ctatgggaca tgaacccaaa acaaaaatgt tcaactctat 4800

 atgattactt ctctcagttt ttggaggaac atggtccctt ggacatgagt 4850

 aacaagatgt tctctgcaga atatgagttt ttcccagaag aaactcgaca 4900

 gatactagaa aaagcaggag gtttaaaacc ttttctcttg ggatgccctc 4950

 gttttgttgt gattgacaac tgtattgcac tgaagaaggt tgcatcacgg 5000

 ctcaagaaaa aaaggaagaa gaaaaacatt aaaacaaaag tagaagaaat 5050

 ttcaaaagca ggggagtatg tacgagttaa actacaactg aatccagctg 5100

 ctagggaatt taaaccagat gtaaagtcta aaccagtgtc agattcatct 5150

 tcagcaccag cttttgaaaa tgtgaaaccc aaacctgtgt ctgcaaattc 5200

 tcccaagcca gcttgtgaag atgtgaaggc caaaccagta tccgacaatt 5250

 cttctagaca agtttctgag gatgggcaac ccaaaggggt ctcttctaat 5300

 tctcctaaac caggctctga ggatgcaaat tacaagcgag tctcctgtaa 5350

 ttcccccaaa ccggttcttg aggatgtgaa accaacttat tgggctcaat 5400

 cccatttggt cacaggatac tgtacgtatc ttcctttcca gagatttgat 5450

 atcacccaga caccgccagc atacataaac gtgttaccag gtttgcccca 5500

 gtacaccagc atatatacac ccttggccag cctttctcct gaatatcagc 5550

 taccaagatc agtaccagtg gtgccgtctt ttgtagccaa tgacagagca 5600

 gataaaaatg ctgctgccta ttttgagggt catcatttga atgctgagaa 5650

 tgttgctggt caccagattg cctctgaaac acagatcctt gagggctctt 5700

 tgggaatatc tgtaaagtca cactgcagca caggtgatgc tcatacagtc 5750

 ctgagtgagt ctaacagaaa tgatgagcac tgtggaaatt ctaacaacaa 5800

 atgtgaagta attccagaaa gcaccagtgc agtaacaaac attccacacg 5850

 tgcagatggt tgccatacag gtatcttgga acataataca ccaagaagtc 5900

 aatactgagc catataatcc ttttgaggaa cgacaagggg aaatttcacg 5950

 gattgaaaag gagcaccaag tattacaaga ccaacttcaa gaagtgtatg 6000

 aaaattatga gcagataaaa cttaagggct tagaagagac cagggacctg 6050

 gaagagaagt tgaaaaggca cttagaagaa aacaagatct caaagacgga 6100

 attagattgg ttccttcaag atttggaaag agaaattaaa aaatggcaac 6150

 aggaaaaaaa agaaatccaa gaaagactaa aatcactgaa gaagaaaatt 6200

 aaaaaggttt caaatgccag tgaaatgtat acccagaaaa atgatggaaa 6250

 ggaaaaggaa catgaattac atctggatca gtcccttgaa atcagcaaca 6300

 cacttacaaa tgagaaaatg aaaatagaag agtatataaa gaaagggaaa 6350

 gaggattatg aagagagtca tcagagagct gtggctgcag aggtatccgt 6400

 acttgaaaac tggaaggaga gtgaagtgta taagctacag atcatggagt 6450

 cacaagcaga agcctttctg aagaagctgg ggctgattag ccgtgatcct 6500

 gcagcatatc ctgacatgga gtctgatata cgttcatggg aattgtttct 6550

 ttctaatgtt acaaaagaaa ttgagaaagc aaagtctcag tttgaagaac 6600

 aaattaaggc aattaaaaat ggttctcggc tcagtgaact ttctaaagtg 6650

 cagatttctg agctttcatt tcctgcctgt aacacggttc atcccgagtt 6700

 actccctgag tcttcaggcc acgatggcca agggcttgtg acttctgcaa 6750

 gcgacgtgac tggaaaccac gcagcacttc acagggatcc tagtgtgttc 6800

 tctgctggtg attccccagg ggaggctcct tctgcgctgt tgccagggcc 6850

 accccctggt cagcctgaag ccactcagct gacagggcca aaacgggctg 6900

 gccaggcagc tctgtcagaa cgaagccctg tggctgatcg gaagcagcct 6950

 gttcctccag gacgtgctgc gcgttcaagc cagtctccaa aaaagccgtt 7000

 caatagtatt attgagcacc tgtcagtggt attcccatgt tacaacagca 7050

 ctgagcttgc tggttttatt aaaaaagtgc gaagcaaaaa caagaactca 7100

 ctctcaggat tgagtattga tgaaattgtc caaagagtga cagaacacat 7150

 tctagatgaa cagaaaaaga aaaagccaaa cccaggaaag gacaagagga 7200

 cttatgagcc cagctctgcc acccccgtga ccaggtcctc ccagggctca 7250

 ccctcggtgg ttgttgcacc atcacccaaa accaaggggc agaaagcaga 7300

 agatgtccct gtgaggattg cactgggtgc aagttcctgt gaaatatgcc 7350

 acgaggtgtt caaatcaaaa aacgtgcgtg tgctcaaatg tgggcacaag 7400

 tatcacaaag ggtgctttaa gcagtggctt aaagggcaga gcgcttgccc 7450

 ggcctgccag ggtcgtgatc tcctgacaga agagtcacct tctggaagag 7500

 gctggcccag tcagaatcag gagctgcctt cctgctcttc taggtagtca 7550

 cacttcacta aagtgtcatc caccagtgtg ttgaatccga agaatgacaa 7600

 ttttctacca ctggtgtaaa aaacaaacat ttgaagaccc ttgtgcattg 7650

 tgtgtcacaa agctaaatac atggaaatcg ttaatatcgc tgatattaag 7700

 taatttcccc actctgagtg aatactttga tgattgccaa cagtggctaa 7750

 taaaatgacg gctaccacac tcatgggtca ctggggctgc gcagggctct 7800

 ttgaggtggg tggcttcttt tggaaagtac tatgaacgtc tcgaagcagt 7850

 attctagtga taagaattct taacatagcc aagcgcccca cgtttgttcc 7900

 ccacgtttgt tccccttttc tgtttgaaaa acctgttctg gtagctccac 7950

 aagagagatg atactgactt tttaaatttt ttacaagagt ctgtattcct 8000

 gatatgccta tatttttcct caaagattct gcattttaag gatgggcata 8050

 agcaaactat attttaataa tttatagtta atgttaaaat attggctgat 8100

 ttagaccaaa agattcaaat ctcctctttg tgaaatccca tctgcatttg 8150

 attttttatt attttatgtt cccccgttag attgttttaa gtgtttgctt 8200

 ttcatctttt atagatgtaa tctgattttc aaaaatcatt aacacttttt 8250

 aattagtatc gactaagact ttttccccct ggaatcgagg ctgtgtgtcc 8300

 gtcatcccag cccccggttg gagcctgctc tttgaactcc gctgccttcc 8350

 ttagcagctt ctgtcctctt ctgtgagtca gtcagcgagt gcttgggatc 8400

 cgcatccagc cgtgctgagc acacaacagg ctgtgtgtgg aaatggccac 8450

 caccattctc cttccccacc ccaccacaaa aagagaagct gtgtctttag 8500

 acaaccctga ggtatctgtg ttacaatcgt tctgtgtttg atatttgtgt 8550

 aaagtatgca tgcagtcttg tactgtgacc taagaacaaa actgtaactg 8600

 cattagaaac catgaaaaaa ttagatattg ttttgtgact tttagacagt 8650

 ggtaaatata gaaccatgaa ttctggtcac attccatttc tctccaacat 8700

 gaaggatcaa aaaatgtttt tcaatgtgtt ctttgttcca ctggaaactt 8750

 agagtcatga gtttatgagc tgatttggtc accttcctct gcctttgttc 8800

 actgtgagtt ctgatgtctt agtgacttag ttcttagaag ctcacgcctt 8850

 agtttgaaac agattctcca cggtggtccc caaaacactg tctgcatatc 8900

 cataagaatt gagcgctatg ggtgttaacg tgcatgagga tcagtttgca 8950

 gcagcaagta caaaaggaga agaggaacat ccgttgaatg agtgtgtttt 9000

 gtacataact tcagatactt gtgaacatgc cttatatttg tccaacaact 9050

 gtcagaataa agaacattct aaaatgag 9078

<210> 1718
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1718
 Met Asp Asn Phe Ala Glu Gly Asp Phe Thr Val Ala Asp Tyr Ala
   1               5                  10                  15

 Leu Leu Glu Asp Cys Pro His Val Asp Asp Cys Val Phe Ala Ala
                  20                  25                  30

 Glu Phe Met Ser Asn Asp Tyr Val Arg Val Thr Gln Leu Tyr Cys
                  35                  40                  45

 Asp Gly Val Gly Val Gln Tyr Lys Asp Tyr Ile Gln Ser Glu Arg
                  50                  55                  60

 Asn Leu Glu Phe Asp Ile Cys Ser Ile Trp Cys Ser Lys Pro Ile
                  65                  70                  75

 Ser Val Leu Gln Asp Tyr Cys Asp Ala Ile Lys Ile Asn Ile Phe
                  80                  85                  90

 Trp Pro Leu Leu Phe Gln His Gln Asn Ser Ser Val Ile Ser Arg
                  95                 100                 105

 Leu His Pro Cys Val Asp Ala Asn Asn Ser Arg Ala Ser Glu Ile
                 110                 115                 120

 Asn Leu Lys Lys Leu Gln His Leu Glu Leu Met Glu Asp Ile Val
                 125                 130                 135

 Asp Leu Ala Lys Lys Val Ala Asn Asp Ser Phe Leu Ile Gly Gly
                 140                 145                 150

 Leu Leu Arg Ile Gly Cys Lys Ile Glu Asn Lys Ile Leu Ala Met
                 155                 160                 165

 Glu Glu Ala Leu Asn Trp Ile Lys Tyr Ala Gly Asp Val Thr Ile
                 170                 175                 180

 Leu Thr Lys Leu Gly Ser Ile Asp Asn Cys Trp Pro Met Leu Ser
                 185                 190                 195

 Ile Phe Phe Thr Glu Tyr Lys Tyr His Ile Thr Lys Ile Val Met
                 200                 205                 210

 Glu Asp Cys Asn Leu Leu Glu Glu Leu Lys Thr Gln Ser Cys Met
                 215                 220                 225

 Asp Cys Ile Glu Glu Gly Glu Leu Met Lys Met Lys Gly Asn Glu
                 230                 235                 240

 Glu Phe Ser Lys Glu Arg Phe Asp Ile Ala Ile Ile Tyr Tyr Thr
                 245                 250                 255

 Arg Ala Ile Glu Tyr Arg Pro Glu Asn Tyr Leu Leu Tyr Gly Asn
                 260                 265                 270

 Arg Ala Leu Cys Phe Leu Arg Thr Gly Gln Phe Arg Asn Ala Leu
                 275                 280                 285

 Gly Asp Gly Lys Arg Ala Thr Ile Leu Lys Asn Thr Trp Pro Lys
                 290                 295                 300

 Gly His Tyr Arg Tyr Cys Asp Ala Leu Ser Met Leu Gly Glu Tyr
                 305                 310                 315

 Asp Trp Ala Leu Gln Ala Asn Ile Lys Ala Gln Lys Leu Cys Lys
                 320                 325                 330

 Asn Asp Pro Glu Gly Ile Lys Asp Leu Ile Gln Gln His Val Lys
                 335                 340                 345

 Leu Gln Lys Gln Ile Glu Asp Leu Gln Gly Arg Thr Ala Asn Lys
                 350                 355                 360

 Asp Pro Ile Lys Ala Phe Tyr Glu Asn Arg Ala Tyr Thr Pro Arg
                 365                 370                 375

 Ser Leu Ser Ala Pro Ile Phe Thr Thr Ser Leu Asn Phe Val Glu
                 380                 385                 390

 Lys Glu Arg Asp Phe Arg Lys Ile Asn His Glu Met Ala Asn Gly
                 395                 400                 405

 Gly Asn Gln Asn Leu Lys Val Ala Asp Glu Ala Leu Lys Val Asp
                 410                 415                 420

 Asp Cys Asp Cys His Pro Glu Phe Ser Pro Pro Ser Ser Gln Pro
                 425                 430                 435

 Pro Lys His Lys Gly Lys Gln Lys Ser Arg Asn Asn Glu Ser Glu
                 440                 445                 450

 Lys Phe Ser Ser Ser Ser Pro Leu Thr Leu Pro Ala Asp Leu Lys
                 455                 460                 465

 Asn Ile Leu Glu Lys Gln Phe Ser Lys Ser Ser Arg Ala Ala His
                 470                 475                 480

 Gln Asp Phe Ala Asn Ile Met Lys Met Leu Arg Ser Leu Ile Gln
                 485                 490                 495

 Asp Gly Tyr Met Ala Leu Leu Glu Gln Arg Cys Arg Ser Ala Ala
                 500                 505                 510

 Gln Ala Phe Thr Glu Leu Leu Asn Gly Leu Asp Pro Gln Lys Ile
                 515                 520                 525

 Lys Gln Leu Asn Leu Ala Met Ile Asn Tyr Val Leu Val Val Tyr
                 530                 535                 540

 Gly Leu Ala Ile Ser Leu Leu Gly Ile Gly Gln Pro Glu Glu Leu
                 545                 550                 555

 Ser Glu Ala Glu Asn Gln Phe Lys Arg Ile Ile Glu His Tyr Pro
                 560                 565                 570

 Ser Glu Gly Leu Asp Cys Leu Ala Tyr Cys Gly Ile Gly Lys Val
                 575                 580                 585

 Tyr Leu Lys Lys Asn Arg Phe Leu Glu Ala Leu Asn His Phe Glu
                 590                 595                 600

 Lys Ala Arg Thr Leu Ile Tyr Arg Leu Pro Gly Val Leu Thr Trp
                 605                 610                 615

 Pro Thr Ser Asn Val Ile Ile Glu Glu Ser Gln Pro Gln Lys Ile
                 620                 625                 630

 Lys Met Leu Leu Glu Lys Phe Val Glu Glu Cys Lys Phe Pro Pro
                 635                 640                 645

 Val Pro Asp Ala Ile Cys Cys Tyr Gln Lys Cys His Gly Tyr Ser
                 650                 655                 660

 Lys Ile Gln Ile Tyr Ile Thr Asp Pro Asp Phe Lys Gly Phe Ile
                 665                 670                 675

 Arg Ile Ser Cys Cys Gln Tyr Cys Lys Ile Glu Phe His Met Asn
                 680                 685                 690

 Cys Trp Lys Lys Leu Lys Thr Thr Thr Phe Asn Asp Lys Ile Asp
                 695                 700                 705

 Lys Asp Phe Leu Gln Gly Ile Cys Leu Thr Pro Asp Cys Glu Gly
                 710                 715                 720

 Val Ile Ser Lys Ile Ile Ile Phe Ser Ser Gly Gly Glu Val Lys
                 725                 730                 735

 Cys Glu Phe Glu His Lys Val Ile Lys Glu Lys Val Pro Pro Arg
                 740                 745                 750

 Pro Ile Leu Lys Gln Lys Cys Ser Ser Leu Glu Lys Leu Arg Leu
                 755                 760                 765

 Lys Glu Asp Lys Lys Leu Lys Arg Lys Ile Gln Lys Lys Glu Ala
                 770                 775                 780

 Lys Lys Leu Ala Gln Glu Arg Met Glu Glu Asp Leu Arg Glu Ser
                 785                 790                 795

 Asn Pro Pro Lys Asn Glu Glu Gln Lys Glu Thr Val Asp Asn Val
                 800                 805                 810

 Gln Arg Cys Gln Phe Leu Asp Asp Arg Ile Leu Gln Cys Ile Lys
                 815                 820                 825

 Gln Tyr Ala Asp Lys Ile Lys Ser Gly Ile Gln Asn Thr Ala Met
                 830                 835                 840

 Leu Leu Lys Glu Leu Leu Ser Trp Lys Val Leu Ser Thr Glu Asp
                 845                 850                 855

 Tyr Thr Thr Cys Phe Ser Ser Arg Asn Phe Leu Asn Glu Ala Val
                 860                 865                 870

 Asp Tyr Val Ile Arg His Leu Ile Gln Glu Asn Asn Arg Val Lys
                 875                 880                 885

 Thr Arg Ile Phe Leu His Val Leu Ser Glu Leu Lys Glu Val Glu
                 890                 895                 900

 Pro Lys Leu Ala Ala Trp Ile Gln Lys Leu Asn Ser Phe Gly Leu
                 905                 910                 915

 Asp Ala Thr Gly Thr Phe Phe Ser Arg Tyr Gly Ala Ser Leu Lys
                 920                 925                 930

 Leu Leu Asp Phe Ser Ile Met Thr Phe Leu Trp Asn Glu Lys Tyr
                 935                 940                 945

 Gly His Lys Leu Asp Ser Ile Glu Gly Lys Gln Leu Asp Tyr Phe
                 950                 955                 960

 Ser Glu Pro Ala Ser Leu Lys Glu Ala Arg Cys Leu Ile Trp Leu
                 965                 970                 975

 Leu Glu Glu His Arg Asp Lys Phe Pro Ala Leu His Ser Ala Leu
                 980                 985                 990

 Asp Glu Phe Phe Asp Ile Met Asp Ser Arg Cys Thr Val Leu Arg
                 995                1000                1005

 Lys Gln Asp Ser Gly Glu Ala Pro Phe Ser Ser Thr Lys Val Lys
                1010                1015                1020

 Asn Lys Ser Lys Lys Lys Lys Pro Lys Asp Ser Lys Pro Met Leu
                1025                1030                1035

 Val Gly Ser Gly Thr Thr Ser Val Thr Ser Asn Asn Glu Ile Ile
                1040                1045                1050

 Thr Ser Ser Glu Asp His Ser Asn Arg Asn Ser Asp Ser Ala Gly
                1055                1060                1065

 Pro Phe Ala Val Pro Asp His Leu Arg Gln Asp Val Glu Glu Phe
                1070                1075                1080

 Glu Ala Leu Tyr Asp Gln His Ser Asn Glu Tyr Val Val Arg Asn
                1085                1090                1095

 Lys Lys Leu Trp Asp Met Asn Pro Lys Gln Lys Cys Ser Thr Leu
                1100                1105                1110

 Tyr Asp Tyr Phe Ser Gln Phe Leu Glu Glu His Gly Pro Leu Asp
                1115                1120                1125

 Met Ser Asn Lys Met Phe Ser Ala Glu Tyr Glu Phe Phe Pro Glu
                1130                1135                1140

 Glu Thr Arg Gln Ile Leu Glu Lys Ala Gly Gly Leu Lys Pro Phe
                1145                1150                1155

 Leu Leu Gly Cys Pro Arg Phe Val Val Ile Asp Asn Cys Ile Ala
                1160                1165                1170

 Leu Lys Lys Val Ala Ser Arg Leu Lys Lys Lys Arg Lys Lys Lys
                1175                1180                1185

 Asn Ile Lys Thr Lys Val Glu Glu Ile Ser Lys Ala Gly Glu Tyr
                1190                1195                1200

 Val Arg Val Lys Leu Gln Leu Asn Pro Ala Ala Arg Glu Phe Lys
                1205                1210                1215

 Pro Asp Val Lys Ser Lys Pro Val Ser Asp Ser Ser Ser Ala Pro
                1220                1225                1230

 Ala Phe Glu Asn Val Lys Pro Lys Pro Val Ser Ala Asn Ser Pro
                1235                1240                1245

 Lys Pro Ala Cys Glu Asp Val Lys Ala Lys Pro Val Ser Asp Asn
                1250                1255                1260

 Ser Ser Arg Gln Val Ser Glu Asp Gly Gln Pro Lys Gly Val Ser
                1265                1270                1275

 Ser Asn Ser Pro Lys Pro Gly Ser Glu Asp Ala Asn Tyr Lys Arg
                1280                1285                1290

 Val Ser Cys Asn Ser Pro Lys Pro Val Leu Glu Asp Val Lys Pro
                1295                1300                1305

 Thr Tyr Trp Ala Gln Ser His Leu Val Thr Gly Tyr Cys Thr Tyr
                1310                1315                1320

 Leu Pro Phe Gln Arg Phe Asp Ile Thr Gln Thr Pro Pro Ala Tyr
                1325                1330                1335

 Ile Asn Val Leu Pro Gly Leu Pro Gln Tyr Thr Ser Ile Tyr Thr
                1340                1345                1350

 Pro Leu Ala Ser Leu Ser Pro Glu Tyr Gln Leu Pro Arg Ser Val
                1355                1360                1365

 Pro Val Val Pro Ser Phe Val Ala Asn Asp Arg Ala Asp Lys Asn
                1370                1375                1380

 Ala Ala Ala Tyr Phe Glu Gly His His Leu Asn Ala Glu Asn Val
                1385                1390                1395

 Ala Gly His Gln Ile Ala Ser Glu Thr Gln Ile Leu Glu Gly Ser
                1400                1405                1410

 Leu Gly Ile Ser Val Lys Ser His Cys Ser Thr Gly Asp Ala His
                1415                1420                1425

 Thr Val Leu Ser Glu Ser Asn Arg Asn Asp Glu His Cys Gly Asn
                1430                1435                1440

 Ser Asn Asn Lys Cys Glu Val Ile Pro Glu Ser Thr Ser Ala Val
                1445                1450                1455

 Thr Asn Ile Pro His Val Gln Met Val Ala Ile Gln Val Ser Trp
                1460                1465                1470

 Asn Ile Ile His Gln Glu Val Asn Thr Glu Pro Tyr Asn Pro Phe
                1475                1480                1485

 Glu Glu Arg Gln Gly Glu Ile Ser Arg Ile Glu Lys Glu His Gln
                1490                1495                1500

 Val Leu Gln Asp Gln Leu Gln Glu Val Tyr Glu Asn Tyr Glu Gln
                1505                1510                1515

 Ile Lys Leu Lys Gly Leu Glu Glu Thr Arg Asp Leu Glu Glu Lys
                1520                1525                1530

 Leu Lys Arg His Leu Glu Glu Asn Lys Ile Ser Lys Thr Glu Leu
                1535                1540                1545

 Asp Trp Phe Leu Gln Asp Leu Glu Arg Glu Ile Lys Lys Trp Gln
                1550                1555                1560

 Gln Glu Lys Lys Glu Ile Gln Glu Arg Leu Lys Ser Leu Lys Lys
                1565                1570                1575

 Lys Ile Lys Lys Val Ser Asn Ala Ser Glu Met Tyr Thr Gln Lys
                1580                1585                1590

 Asn Asp Gly Lys Glu Lys Glu His Glu Leu His Leu Asp Gln Ser
                1595                1600                1605

 Leu Glu Ile Ser Asn Thr Leu Thr Asn Glu Lys Met Lys Ile Glu
                1610                1615                1620

 Glu Tyr Ile Lys Lys Gly Lys Glu Asp Tyr Glu Glu Ser His Gln
                1625                1630                1635

 Arg Ala Val Ala Ala Glu Val Ser Val Leu Glu Asn Trp Lys Glu
                1640                1645                1650

 Ser Glu Val Tyr Lys Leu Gln Ile Met Glu Ser Gln Ala Glu Ala
                1655                1660                1665

 Phe Leu Lys Lys Leu Gly Leu Ile Ser Arg Asp Pro Ala Ala Tyr
                1670                1675                1680

 Pro Asp Met Glu Ser Asp Ile Arg Ser Trp Glu Leu Phe Leu Ser
                1685                1690                1695

 Asn Val Thr Lys Glu Ile Glu Lys Ala Lys Ser Gln Phe Glu Glu
                1700                1705                1710

 Gln Ile Lys Ala Ile Lys Asn Gly Ser Arg Leu Ser Glu Leu Ser
                1715                1720                1725

 Lys Val Gln Ile Ser Glu Leu Ser Phe Pro Ala Cys Asn Thr Val
                1730                1735                1740

 His Pro Glu Leu Leu Pro Glu Ser Ser Gly His Asp Gly Gln Gly
                1745                1750                1755

 Leu Val Thr Ser Ala Ser Asp Val Thr Gly Asn His Ala Ala Leu
                1760                1765                1770

 His Arg Asp Pro Ser Val Phe Ser Ala Gly Asp Ser Pro Gly Glu
                1775                1780                1785

 Ala Pro Ser Ala Leu Leu Pro Gly Pro Pro Pro Gly Gln Pro Glu
                1790                1795                1800

 Ala Thr Gln Leu Thr Gly Pro Lys Arg Ala Gly Gln Ala Ala Leu
                1805                1810                1815

 Ser Glu Arg Ser Pro Val Ala Asp Arg Lys Gln Pro Val Pro Pro
                1820                1825                1830

 Gly Arg Ala Ala Arg Ser Ser Gln Ser Pro Lys Lys Pro Phe Asn
                1835                1840                1845

 Ser Ile Ile Glu His Leu Ser Val Val Phe Pro Cys Tyr Asn Ser
                1850                1855                1860

 Thr Glu Leu Ala Gly Phe Ile Lys Lys Val Arg Ser Lys Asn Lys
                1865                1870                1875

 Asn Ser Leu Ser Gly Leu Ser Ile Asp Glu Ile Val Gln Arg Val
                1880                1885                1890

 Thr Glu His Ile Leu Asp Glu Gln Lys Lys Lys Lys Pro Asn Pro
                1895                1900                1905

 Gly Lys Asp Lys Arg Thr Tyr Glu Pro Ser Ser Ala Thr Pro Val
                1910                1915                1920

 Thr Arg Ser Ser Gln Gly Ser Pro Ser Val Val Val Ala Pro Ser
                1925                1930                1935

 Pro Lys Thr Lys Gly Gln Lys Ala Glu Asp Val Pro Val Arg Ile
                1940                1945                1950

 Ala Leu Gly Ala Ser Ser Cys Glu Ile Cys His Glu Val Phe Lys
                1955                1960                1965

 Ser Lys Asn Val Arg Val Leu Lys Cys Gly His Lys Tyr His Lys
                1970                1975                1980

 Gly Cys Phe Lys Gln Trp Leu Lys Gly Gln Ser Ala Cys Pro Ala
                1985                1990                1995

 Cys Gln Gly Arg Asp
                2000

<210> 1719
<211> 2033
<212> DNA
<213> Homo sapien

<400> 1719
 gaattccggg actgagctct tgaagacttg ggtccttggt cgcaggtgga 50

 gcgacgggtc tcactccatt gcccaggcca gagtgcggga tatttgataa 100

 gaaacttcag tgaaggccgg gcgcggtgct catgcccgta atcccagcat 150

 tttcggaggc cgaggcatca tggaccgatc taaagaaaac tgcatttcag 200

 gacctgttaa ggctacagct ccagttggag gtccaaaacg tgttctcgtg 250

 actcagcaat ttccttgtca gaatccatta cctgtaaata gtggccaggc 300

 tcagcgggtc ttgtgtcctt caaattcttc ccagcgcgtt cctttgcaag 350

 cacaaaagct tgtctccagt cacaagccgg ttcagaatca gaagcagaag 400

 caattgcagg caaccagtgt acctcatcct gtctccaggc cactgaataa 450

 cacccaaaag agcaagcagc ccctgccatc gcacctgaaa ataatcctga 500

 ggaggaactg gcatcaaaac agaaaaatga agaatcaaaa agaggcagtg 550

 gctttggaag actttgaaat tggtcgccct ctgggtaaag gaaagtttgg 600

 taatgtttat ttggcaagag aaaagcaaag caagtttatt ctggctctta 650

 aagtgttatt taaagctcag ctggagaaag ccggagtgga gcatcagctc 700

 agaagagaag tagaaataca gtcccacctt cggcatccta atattcttag 750

 actgtatggt tatttccatg atgctaccag agtctaccta attctggaat 800

 atgcaccact tggaacagtt tatagagaac ttcagaaact ttcaaagttt 850

 gatgagcaga gaactgctaa cttatataac agaattgcaa atgccctgtc 900

 ttactgtcat tcgaagagag ttattcatag agacattaag ccagagaact 950

 tacttcttgg atcagctgga gagcttaaaa ttgcagattt tgggtggtca 1000

 gtacatgctc catcttccag gaggaccact ctctgtggca ccctggacta 1050

 cctgccccct gaaatgattg aaggtcggat gcatgatgag aaggtggatc 1100

 tctggagcct tggagttctt tgctatgaat ttttagttgg gaagcctcct 1150

 tttgaggcaa acacatacca agagacctac aaaagaatat cacgggttga 1200

 attcacattc cctgactttg taacagaggg agccagggac ctcatttcaa 1250

 gactgttgaa gcataatccc agccagaggc caatgctcag agaagtactt 1300

 gaacacccct ggatcacagc aaattcatca aaaccatcaa attgccaaaa 1350

 caaagaatca gctagcaaac agtcttagga atcgtgcagg gggagaaatc 1400

 cttgagccag ggctgccata taacctgaca ggaacatgct actgaagttt 1450

 attttaccat tgactgctgc cctcaatcta gaacgctaca caagaaatat 1500

 tttgttttta ctcagcaggt gtgccttaac ctccctattc agaaagctcc 1550

 acatcaataa acatgacact ctgaagtgaa agtagccacg agaattgtgc 1600

 tacttatact ggaacataat ctggaggcaa ggttcgactg cagtcgaacc 1650

 ttgcctccag attatgaacc agtataagta gcacaattct cgtggctact 1700

 ttcacttcag agtgtcatgt ttattgatgt ggagctttct gaatagggag 1750

 gttaaggcac acctgctgag taaaacaaat atttcttgtg tagcgttctt 1800

 aggaatctgg tgtctgtccg gccccggtag gcctgttggg tttctagtcc 1850

 tccttaccat catctccata tgagagtgtg aaaataggaa cacgtgctct 1900

 acctccattt agggatttgc ttgggataca gaagaggcca tgtgtctcag 1950

 agctgttaag ggcttatttt tttaaaacat tggagtcata gcatgtgtgt 2000

 aaactttaaa tatgcaggcc ttcgtggctc gag 2033

<210> 1720
<211> 402
<212> PRT
<213> Homo sapien

<400> 1720
 Met Asp Arg Ser Lys Glu Asn Cys Ile Ser Gly Pro Val Lys Ala
   1               5                  10                  15

 Thr Ala Pro Val Gly Gly Pro Lys Arg Val Leu Val Thr Gln Gln
                  20                  25                  30

 Phe Pro Cys Gln Asn Pro Leu Pro Val Asn Ser Gly Gln Ala Gln
                  35                  40                  45

 Arg Val Leu Cys Pro Ser Asn Ser Ser Gln Arg Val Pro Leu Gln
                  50                  55                  60

 Ala Gln Lys Leu Val Ser Ser His Lys Pro Val Gln Asn Gln Lys
                  65                  70                  75

 Gln Lys Gln Leu Gln Ala Thr Ser Val Pro His Pro Val Ser Arg
                  80                  85                  90

 Pro Leu Asn Asn Thr Gln Lys Ser Lys Gln Pro Leu Pro Ser His
                  95                 100                 105

 Leu Lys Ile Ile Leu Arg Arg Asn Trp His Gln Asn Arg Lys Met
                 110                 115                 120

 Lys Asn Gln Lys Glu Ala Val Ala Leu Glu Asp Phe Glu Ile Gly
                 125                 130                 135

 Arg Pro Leu Gly Lys Gly Lys Phe Gly Asn Val Tyr Leu Ala Arg
                 140                 145                 150

 Glu Lys Gln Ser Lys Phe Ile Leu Ala Leu Lys Val Leu Phe Lys
                 155                 160                 165

 Ala Gln Leu Glu Lys Ala Gly Val Glu His Gln Leu Arg Arg Glu
                 170                 175                 180

 Val Glu Ile Gln Ser His Leu Arg His Pro Asn Ile Leu Arg Leu
                 185                 190                 195

 Tyr Gly Tyr Phe His Asp Ala Thr Arg Val Tyr Leu Ile Leu Glu
                 200                 205                 210

 Tyr Ala Pro Leu Gly Thr Val Tyr Arg Glu Leu Gln Lys Leu Ser
                 215                 220                 225

 Lys Phe Asp Glu Gln Arg Thr Ala Asn Leu Tyr Asn Arg Ile Ala
                 230                 235                 240

 Asn Ala Leu Ser Tyr Cys His Ser Lys Arg Val Ile His Arg Asp
                 245                 250                 255

 Ile Lys Pro Glu Asn Leu Leu Leu Gly Ser Ala Gly Glu Leu Lys
                 260                 265                 270

 Ile Ala Asp Phe Gly Trp Ser Val His Ala Pro Ser Ser Arg Arg
                 275                 280                 285

 Thr Thr Leu Cys Gly Thr Leu Asp Tyr Leu Pro Pro Glu Met Ile
                 290                 295                 300

 Glu Gly Arg Met His Asp Glu Lys Val Asp Leu Trp Ser Leu Gly
                 305                 310                 315

 Val Leu Cys Tyr Glu Phe Leu Val Gly Lys Pro Pro Phe Glu Ala
                 320                 325                 330

 Asn Thr Tyr Gln Glu Thr Tyr Lys Arg Ile Ser Arg Val Glu Phe
                 335                 340                 345

 Thr Phe Pro Asp Phe Val Thr Glu Gly Ala Arg Asp Leu Ile Ser
                 350                 355                 360

 Arg Leu Leu Lys His Asn Pro Ser Gln Arg Pro Met Leu Arg Glu
                 365                 370                 375

 Val Leu Glu His Pro Trp Ile Thr Ala Asn Ser Ser Lys Pro Ser
                 380                 385                 390

 Asn Cys Gln Asn Lys Glu Ser Ala Ser Lys Gln Ser
                 395                 400

<210> 1721
<211> 3686
<212> DNA
<213> Homo sapien

<400> 1721
 aggacagtac agtgccttac ttgcaagatg tgcaagcaca caagacctat 50

 gaagaactgt ctcccaacaa aggatacatg cagaaggaga aaaaactctc 100

 ttaaacaaaa agaggcagag ccggcaggga ccgagcgggt gcctcagtct 150

 ccttcccctc ccctcgcctg tcctcgccat cttcttctca cagccggacc 200

 ggaactatgt gatcccggaa gttccgggtc ctttggccct atatgatccc 250

 ggaagttccg gggcttttgg acctctgtga ttccggaagt tccggggcgt 300

 tccggggcgt tctggggcct ttggagcgtg ggataagcag taatggcgga 350

 ggctgcagct cccggaacaa cagtcacaac atcgggagca ggagcagcag 400

 cggcggaggc ggcggagacg gcggaagcag tctccccgac tccgatcccc 450

 acagtcaccg ccccgtcccc gagggcgggc ggaggggtcg gcggcagcga 500

 cggcagcgac ggtagtggcg gcaggggcga cagtggcgcg tatgacggca 550

 gcggtgcgtg cggcggcagc gacgcgtgcg atggcagcgg cgacagcagc 600

 ggcgacagct ggactaaaca ggtcacttgt agatatttta agtatgggat 650

 ttgtaaggaa ggagataact gtcgctactc gcatgacctc tctgaccgtc 700

 tgtgtggtgt agtgtgcaag tattttcagc gagggtgctg tgtttatgga 750

 gaccgctgca gatgtgaaca tagcaagcca ttgaaacagg aagaagcaac 800

 tgctacagag ctaactacaa agtcatccct tgctgcttcc tcaagtctct 850

 catcaatagt tggaccactt gttgaaatga atacaaacga agctgagtca 900

 agaaattcaa attttgcaac tgtagtagca ggttcagagg actgggcgaa 950

 tgccattgag tttgttcctg ggcaacccta ctgtggccgt actgtgcctt 1000

 cctgcactga agcacccctg cagggctcag tgaccaagga agaatcagag 1050

 gaagagcaaa ccgccgtgga aacaaagaag cagctgtgcc cctatgctgc 1100

 agtgggacag tgccgatatg gggagaactg tgtgtatctc cacggagatt 1150

 tatgtgacat gtgtgggctg caggtcctgc atccgatgga tgctgcccag 1200

 agatcacagc atatacaagc gtgcattgaa gcccatgaga aagacatgga 1250

 gttctcattt gctgtgcagc gcagcaagga caaggtgtgt gggatctgca 1300

 tggaggtggt ctatgagaaa gccaacccca acgagcaccg cttcgggatc 1350

 ctctccaact gcaaccacac cttctgtctc aagtgcattc gcaagtggag 1400

 gagtgctaag gaatttgaga gcaggatcgt caagtcctgc ccacaatgcc 1450

 gaatcacatc taactttgtc attccaagtg agtactgggt ggaggagaaa 1500

 gaagagaagc agaaactcat tcagaaatac aaggaggcaa tgagcaacaa 1550

 ggcatgcaag tattttgatg aaggacgtgg gagctgccca tttggagaga 1600

 actgttttta caagcatatg taccctgatg gccgcagaga ggagccacag 1650

 agacagcaag tgggaacatc aagcagaaac ccaggccaac aaaggaacca 1700

 cttctgggaa ttctttgagg aaggagcgaa cagcaacccc tttgacgatg 1750

 aagaagaggc tgtcaccttt gagctgggtg agatgttgct tatgctttag 1800

 gctgcaggtg gggacgacaa actgacagac tctgaaaatg agtgggactt 1850

 gttttgtgat gaagaatttt atgtcttaga tctatagaaa ccttgcgtag 1900

 tgtgtgagct ggtctgctga ccccagatag cagctgtccc ctgtggtggt 1950

 gtggcagtgc ctatgttctc tcctaggcag acctatcaac tccaggtgct 2000

 gcggttaaga atatgtaccc agggcctgtc ttgtcaaccc ctcacctttc 2050

 cccaaggagt gtgttgtttt ccctgttgga aaaagttaca aaaataaatg 2100

 ttaaaggttt tttttgtttt ttgttttatt gagacagagt cccactctgt 2150

 cacccaggct ggagtgcagt ggtgcaatct tggctcactg caacctccgt 2200

 cttccgggtt caagccattc tcctgtctca gcctcccaag ttgctgggac 2250

 tacaggtgca tgctacaatg cccagctaat ttttctcatt tttagtagaa 2300

 acggggtttc accatattgg tcaggctggt ctcgaactcc tgacctcagg 2350

 tgatccacct gccactacct tccaaagtgc tgggattaca ggcgtcagcc 2400

 accatgccca gccttaaagt tagttttttg taacaggcat gagccaccgc 2450

 gcctggcttt aaagttcgtt ttttgtaaca ggcataagcc actgtgcctg 2500

 gccttaaagt tagttttttt gtaacacgaa tttaactgtt ggacagttag 2550

 tttagatgtg ttgcatcatc tgttttcaac cagattgtgt ttatggactt 2600

 ttcacacact aattttgagg accccaggtt caaaagtaaa agcagtggcc 2650

 ctgctttggg gtccaataat aggagtgatg ggtgaaggga cctaagctgg 2700

 ccagtagcct tctgctccag acatgggacg cggatccttg aggtttctgg 2750

 ttaaatctgc acatctgtgt ttttatatct gttccctacc cctgtaatcc 2800

 ctaccgcatg cactagttct gtagttttgg tctctcgttt aattgtatgc 2850

 aagtagtact actgggtaac cagagccaag cgtgaatgtg ttcagatttc 2900

 tactgttttg catgatagga aaattgagaa agaatacata taaaagatat 2950

 agaggcataa catcaatgca gagttggaag ttgacctcca cggggtgaca 3000

 tggtgtgtgt gagtgtgggt gtgtgagtgt gggtgtgtga taagcttctc 3050

 aaacctgcat agatgcagta ttcttggctt tggtagaaag ccttggttta 3100

 aggctgggcg cggtggctca cgcctgtaat cccagcactt tgggaggctg 3150

 aggcggccgg atcacaaggc caggagatcg agaccatcct gtgaatggcg 3200

 aaaccctgtc tctactaaaa atacaaaaaa ttagccgggc gtagtggcgg 3250

 gcgcctgtag tcccagctac tctggaggct gaggcgggag aatggtgtga 3300

 acctgggagg cggagcttgc aatgaactga gaatgtgcca ctggactccc 3350

 agcctgggtg acagagcgag actctgtctc aaacaaaaaa aaacaaaaac 3400

 ggaaaccctt ggtttagggg tttaagtctt atgtggtggt taagatctta 3450

 aaggacaaag cagtatattg gtagttatca atatagcagt actagctctg 3500

 tttatataaa tagagaaatg gagttagcca tagaggttaa aactacctgg 3550

 ttatcccata tattaaccca aactgggtct tggatacaca gttgtattta 3600

 atgttttacg atctagcctt tccagtatag gcacttcctg aaaaaccttt 3650

 gtcctcattt ggggcatttt gttgttgggt ttcgcc 3686

<210> 1722
<211> 485
<212> PRT
<213> Homo sapien

<400> 1722
 Met Ala Glu Ala Ala Ala Pro Gly Thr Thr Val Thr Thr Ser Gly
   1               5                  10                  15

 Ala Gly Ala Ala Ala Ala Glu Ala Ala Glu Thr Ala Glu Ala Val
                  20                  25                  30

 Ser Pro Thr Pro Ile Pro Thr Val Thr Ala Pro Ser Pro Arg Ala
                  35                  40                  45

 Gly Gly Gly Val Gly Gly Ser Asp Gly Ser Asp Gly Ser Gly Gly
                  50                  55                  60

 Arg Gly Asp Ser Gly Ala Tyr Asp Gly Ser Gly Ala Cys Gly Gly
                  65                  70                  75

 Ser Asp Ala Cys Asp Gly Ser Gly Asp Ser Ser Gly Asp Ser Trp
                  80                  85                  90

 Thr Lys Gln Val Thr Cys Arg Tyr Phe Lys Tyr Gly Ile Cys Lys
                  95                 100                 105

 Glu Gly Asp Asn Cys Arg Tyr Ser His Asp Leu Ser Asp Arg Leu
                 110                 115                 120

 Cys Gly Val Val Cys Lys Tyr Phe Gln Arg Gly Cys Cys Val Tyr
                 125                 130                 135

 Gly Asp Arg Cys Arg Cys Glu His Ser Lys Pro Leu Lys Gln Glu
                 140                 145                 150

 Glu Ala Thr Ala Thr Glu Leu Thr Thr Lys Ser Ser Leu Ala Ala
                 155                 160                 165

 Ser Ser Ser Leu Ser Ser Ile Val Gly Pro Leu Val Glu Met Asn
                 170                 175                 180

 Thr Asn Glu Ala Glu Ser Arg Asn Ser Asn Phe Ala Thr Val Val
                 185                 190                 195

 Ala Gly Ser Glu Asp Trp Ala Asn Ala Ile Glu Phe Val Pro Gly
                 200                 205                 210

 Gln Pro Tyr Cys Gly Arg Thr Val Pro Ser Cys Thr Glu Ala Pro
                 215                 220                 225

 Leu Gln Gly Ser Val Thr Lys Glu Glu Ser Glu Glu Glu Gln Thr
                 230                 235                 240

 Ala Val Glu Thr Lys Lys Gln Leu Cys Pro Tyr Ala Ala Val Gly
                 245                 250                 255

 Gln Cys Arg Tyr Gly Glu Asn Cys Val Tyr Leu His Gly Asp Leu
                 260                 265                 270

 Cys Asp Met Cys Gly Leu Gln Val Leu His Pro Met Asp Ala Ala
                 275                 280                 285

 Gln Arg Ser Gln His Ile Gln Ala Cys Ile Glu Ala His Glu Lys
                 290                 295                 300

 Asp Met Glu Phe Ser Phe Ala Val Gln Arg Ser Lys Asp Lys Val
                 305                 310                 315

 Cys Gly Ile Cys Met Glu Val Val Tyr Glu Lys Ala Asn Pro Asn
                 320                 325                 330

 Glu His Arg Phe Gly Ile Leu Ser Asn Cys Asn His Thr Phe Cys
                 335                 340                 345

 Leu Lys Cys Ile Arg Lys Trp Arg Ser Ala Lys Glu Phe Glu Ser
                 350                 355                 360

 Arg Ile Val Lys Ser Cys Pro Gln Cys Arg Ile Thr Ser Asn Phe
                 365                 370                 375

 Val Ile Pro Ser Glu Tyr Trp Val Glu Glu Lys Glu Glu Lys Gln
                 380                 385                 390

 Lys Leu Ile Gln Lys Tyr Lys Glu Ala Met Ser Asn Lys Ala Cys
                 395                 400                 405

 Lys Tyr Phe Asp Glu Gly Arg Gly Ser Cys Pro Phe Gly Glu Asn
                 410                 415                 420

 Cys Phe Tyr Lys His Met Tyr Pro Asp Gly Arg Arg Glu Glu Pro
                 425                 430                 435

 Gln Arg Gln Gln Val Gly Thr Ser Ser Arg Asn Pro Gly Gln Gln
                 440                 445                 450

 Arg Asn His Phe Trp Glu Phe Phe Glu Glu Gly Ala Asn Ser Asn
                 455                 460                 465

 Pro Phe Asp Asp Glu Glu Glu Ala Val Thr Phe Glu Leu Gly Glu
                 470                 475                 480

 Met Leu Leu Met Leu
                 485

<210> 1723
<211> 3273
<212> DNA
<213> Homo sapien

<400> 1723
 actggagtct ctgagcagcc attgaagggg aaggaactgc gggtgtgtgt 50

 gtgtatgtgt gtgtgtatgt gtgtgcgcgc gtgcgtgcgt gtgtgtgcgc 100

 gcgctagtgt gtggacaagg aggtgggggc agctgagtta gagtcccaac 150

 tcttggactc catttgctat tctcttcttt ctcccccaca cctatctggt 200

 ggtggtagtg ggcgtttata tttgcgttcc ttttcattca tttctaaatc 250

 tcttaaaaat tttgggttgg gggtattggg gaaggcagga aagggaaaag 300

 gagagtagta gctgaagagc aagaggagga catggagatg aagaagaaga 350

 ttaacctgga gttaaggaac agatccccgg aggaggtgac agagttagtc 400

 cttgataatt gcctgtgtgt caatggggaa attgaaggcc tgaatgatac 450

 tttcaaagaa ctagaatttc tgagtatggc taatgtggaa ctaagttcgc 500

 tggcccggct tcccagctta aataaacttc gaaaattgga gcttagtgat 550

 aatataattt ctggaggctt ggaagtcctg gcagagaaat gtccaaatct 600

 tacctacctc aatctgagtg gaaacaaaat aaaagatctc agtacagtag 650

 aagctctgca aaatcttaaa aatttgaaaa gtcttgacct gtttaactgt 700

 gagatcacaa acctggaaga ttatagagaa agtatttttg aactactgca 750

 gcaaatcaca tacttagatg gatttgatca ggaggataat gaagcgccgg 800

 actctgaaga ggaggatgat gaggatggcg atgaagatga tgaagaggaa 850

 gaggaaaatg aagctggtcc accggaagga tatgaggaag aggaggagga 900

 agaggaagag gaggatgagg atgaggatga agatgaagat gaagcaggtt 950

 cagagttggg agagggagaa gaggaagtgg gcctctcata cttaatgaaa 1000

 gaagaaattc aggatgaaga agatgatgat gactatgttg aagaagggga 1050

 agaagaggaa gaagaggaag aaggaggtct tcgaggggag aagaggaaac 1100

 gagatgctga agacgatgga gaggaagaag atgactagat cattctaaga 1150

 ccagattctc taatgtttct gggtgtgcaa tagagtgatc acatctttgt 1200

 ttcttcatgt acgatagcta tccctacaga agataatgtg taacttttta 1250

 taggaaaagt gtggttttac tatttttgcc ttatcattcc aaataagaac 1300

 tagtctgtta atgatcatat tgtatgtaga gaaaaatttt cattgactcc 1350

 cattgtggaa ttccctagca atttatttag acttaatttt ttaaattcaa 1400

 gcttactgta ttagtcattt ttagcccata attaaaacat gatcactttt 1450

 acacaggtgt agtatggtgc atttcattcc ttatttataa attaactgaa 1500

 attacagttt gctataatat aaaatgacaa tagtctcttg agtggtaagt 1550

 tggttatttt tttagaggtg atccaggaat ctttagtttg aaggcagtta 1600

 cctttttttt tttttttttt ttgactaaga gtgtttggtt gcttttttgt 1650

 cacaagtaac ttggaaaata gaagcagaat agtaaaggtt ctattcagca 1700

 acatagttca tggattttgt ggaggttcta ttcagtaata tggttcatgg 1750

 atttagtggt gactgataag attttatttt tgaaggaaaa attgcttata 1800

 ctaagtccag agacatgcag gtgagccctt ttgtcaggct gcaaatcatg 1850

 acatgccgat ggttgtttat tttgttttta ggtgtgcatt ctttttcttc 1900

 ttagcaattc ctttatgatc accttccctt cttgtttcac tccctcccgc 1950

 tctctcaaaa ggaacttggg aaacttgtga aacccaggaa aacctttagt 2000

 cttatacctc aactaccttt cagtcctgtc tgggttttaa ataagtgaag 2050

 tagaagaaat tgagtatttt ctgacataag aatatattat caatacagtt 2100

 ttatgcagta agctctcctt accataaatg tttcttggtt gacaacatct 2150

 aagacaatat tagtgggatg aagaaagaaa agcaggggtg cttttggaag 2200

 cagtgttagt gttcctcaaa agtcggaaca attgcctgtt gatatattaa 2250

 taagacatta aagtcaaatt ttaatgttgg cctctcaaat gatttggata 2300

 ccactctgca aagtatttct aacctttaat tcccagtttt aaaacagata 2350

 taataatagc atttaattgg aatatactag gcagctggaa aagtatttga 2400

 aactaaattg acattaaaat taagatttgt tttcaagtgg atgtccatta 2450

 aaagtagaaa aatatttggg ataagtgagt gtgtatttcc ttacatggct 2500

 actaaataaa atataatgag tatacaagta tatctcctct tttgctatgg 2550

 aggctccatg ttcaaggcaa tggcttttta aatcttggct atctaaaatt 2600

 ttttcccttt gttttgaata tttgtaagtt tttaagaagt tagtgtcagc 2650

 aaattaattg aagttatgct tctatactgg gacatattta aatactgagt 2700

 atagtactgc tgctactgct tctacaatgt aaaatgtatg acttggtgtt 2750

 ttaaagtaaa aattatgatg ttacttgtgg agaaactaaa aatgttgtac 2800

 aactgaccga aagaaaaccc ttggggataa gtttagtgag gggattggaa 2850

 tccccaaaaa gataacattt ttcttctgct tttaaaaact gaaattccct 2900

 gttctagttc ctaacaattc tcattacata ctatgccaga ttacaaaata 2950

 cttattttta aaatgaaatc tatatattga ctttcttatc aatcatctta 3000

 ctgtgcaatc aaaattagag tactttggtt tgaaaacaac acttagagcc 3050

 tccagataac ttttaagact tatttagctt tgtgggtggt attttcatgc 3100

 aaataagtaa gggtgggttt tatattttgt agaagttttc ggtcctattt 3150

 taatgctttt gtatggcagt atgtatatat tgtgttaagt tcctcaagaa 3200

 tctccttaaa aactttgaag ttaatacttt tgtgcaactg tgttttgaat 3250

 aaagccatga cagtgttaaa aac 3273

<210> 1724
<211> 268
<212> PRT
<213> Homo sapien

<400> 1724
 Met Glu Met Lys Lys Lys Ile Asn Leu Glu Leu Arg Asn Arg Ser
   1               5                  10                  15

 Pro Glu Glu Val Thr Glu Leu Val Leu Asp Asn Cys Leu Cys Val
                  20                  25                  30

 Asn Gly Glu Ile Glu Gly Leu Asn Asp Thr Phe Lys Glu Leu Glu
                  35                  40                  45

 Phe Leu Ser Met Ala Asn Val Glu Leu Ser Ser Leu Ala Arg Leu
                  50                  55                  60

 Pro Ser Leu Asn Lys Leu Arg Lys Leu Glu Leu Ser Asp Asn Ile
                  65                  70                  75

 Ile Ser Gly Gly Leu Glu Val Leu Ala Glu Lys Cys Pro Asn Leu
                  80                  85                  90

 Thr Tyr Leu Asn Leu Ser Gly Asn Lys Ile Lys Asp Leu Ser Thr
                  95                 100                 105

 Val Glu Ala Leu Gln Asn Leu Lys Asn Leu Lys Ser Leu Asp Leu
                 110                 115                 120

 Phe Asn Cys Glu Ile Thr Asn Leu Glu Asp Tyr Arg Glu Ser Ile
                 125                 130                 135

 Phe Glu Leu Leu Gln Gln Ile Thr Tyr Leu Asp Gly Phe Asp Gln
                 140                 145                 150

 Glu Asp Asn Glu Ala Pro Asp Ser Glu Glu Glu Asp Asp Glu Asp
                 155                 160                 165

 Gly Asp Glu Asp Asp Glu Glu Glu Glu Glu Asn Glu Ala Gly Pro
                 170                 175                 180

 Pro Glu Gly Tyr Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp
                 185                 190                 195

 Glu Asp Glu Asp Glu Asp Glu Asp Glu Ala Gly Ser Glu Leu Gly
                 200                 205                 210

 Glu Gly Glu Glu Glu Val Gly Leu Ser Tyr Leu Met Lys Glu Glu
                 215                 220                 225

 Ile Gln Asp Glu Glu Asp Asp Asp Asp Tyr Val Glu Glu Gly Glu
                 230                 235                 240

 Glu Glu Glu Glu Glu Glu Glu Gly Gly Leu Arg Gly Glu Lys Arg
                 245                 250                 255

 Lys Arg Asp Ala Glu Asp Asp Gly Glu Glu Glu Asp Asp
                 260                 265

<210> 1725
<211> 5600
<212> DNA
<213> Homo sapien

<400> 1725
 ggagtgggcc aggccgccag ccccgccagc cccgccagcc ccgccagccc 50

 cgcgatggct tgggccgcgc tcctcggcct cctggccgca ctgttgctgc 100

 tgctgctact gagccgccgc cgcacgcggc gacctggtga gcctcccctg 150

 gacctgggca gcatcccctg gttggggtat gccttggact ttggaaaaga 200

 tgctgccagc ttcctcacga ggatgaagga gaagcacggt gacatcttta 250

 ctatactggt tgggggcagg tatgtcaccg ttctcctgga cccacactcc 300

 tacgacgcgg tggtgtggga gcctcgcacc aggctcgact tccatgccta 350

 tgccatcttc ctcatggaga ggatttttga tgtgcagctt ccacattaca 400

 gccccagtga tgaaaaggcc aggatgaaac tgactcttct ccacagagag 450

 ctccaggcac tcacagaagc catgtatacc aacctccatg cagtgctgtt 500

 gggcgatgct acagaagcag gcagtggctg gcacgagatg ggtctcctcg 550

 acttctccta cagcttcctg ctcagagccg gctacctgac tctttacgga 600

 attgaggcgc tgccacgcac ccatgaaagc caggcccagg accgcgtcca 650

 ctcagctgat gtcttccaca cctttcgcca gctcgaccgg ctgctcccca 700

 aactggcccg tggctccctg tcagtggggg acaaggacca catgtgcagt 750

 gtcaaaagtc gcctgtggaa gctgctatcc ccagccaggc tggccaggcg 800

 ggcccaccgg agcaaatggc tggagagtta cctgctgcac ctggaggaga 850

 tgggtgtgtc agaggagatg caggcacggg ccctggtgct gcagctgtgg 900

 gccacacagg ggaatatggg tcccgctgcc ttctggctcc tgctcttcct 950

 tctcaagaat cctgaagccc tggctgctgt ccgcggagag ctcgagagta 1000

 tcctttggca agcggagcag cctgtctcgc agacgaccac tctcccacag 1050

 aaggttctag acagcacacc tgtgcttgat agcgtgctga gtgagagcct 1100

 caggcttaca gctgccccct tcatcacccg cgaggttgtg gtggacctgg 1150

 ccatgcccat ggcagacggg cgagaattca acctgcgacg tggtgaccgc 1200

 ctcctcctct tccccttcct gagcccccag agagacccag aaatctacac 1250

 agacccagag gtatttaaat acaaccgatt cctgaaccct gacggatcag 1300

 agaagaaaga cttttacaag gatgggaaac ggctgaagaa ttacaacatg 1350

 ccctgggggg cggggcacaa tcactgcctg gggaggagtt atgcggtcaa 1400

 cagcatcaaa caatttgtgt tccttgtgct ggtgcacttg gacttggagc 1450

 tgatcaacgc agatgtggag atccctgagt ttgacctcag caggtacggc 1500

 ttcggtctga tgcagccgga acacgacgtg cccgtccgct accgcatccg 1550

 cccatgacac agggagcaga tggatccacg tgctcgcctc tgcccagcct 1600

 gccccagcct gccccagcct cccagctttc tgtgtgcaca gttggcccgg 1650

 gtgcaggtgc tagcattacc acttccctgc ttttctccca gaaggctggg 1700

 tccaggggag ggaaaagcta agagggtgaa caaagaaaag acattgaaag 1750

 ctctatggat tatccactgc aaagttttct ttccaaaatc aggctttgtc 1800

 tgctcccaat tcacctcgtt actctcacct cgtgatatcc acaaatgcta 1850

 ttcagataag gcagaactag gagtcttcac tgctctgccc ccaactcccg 1900

 gaggtgtcac cttcctagtt cttatgagct agcatggccc gggccttatc 1950

 cagtcaaagc ggatgctggc cacagaaagg ccactcagga tgtcctttgt 2000

 gtccattgat gtcattcagc agtcagtccc ccaataatcc ttaaactagc 2050

 taaaaccaaa ggagtccctt agaagatctg cttccctggg gccccatttg 2100

 ccagattgcc ccattgctca cactacttga gaaaatgcag gagagcttcc 2150

 cccaaggctg atgcattccc ggtgcagaac aggggcaccc tccaaacact 2200

 gggctctgag gagtggagtt ctctgttcta gagtgacagg caccagatgg 2250

 gatgggcttt ctcagtgtca gcactcaggt agggagctaa ggaagacaca 2300

 gcccagacaa gatggctgga aggagccagc caggactcct tagactgatc 2350

 aagccaaaaa agaaggtgcc gatttcatgc attctagtgc agaagcccca 2400

 actgtgatca cgatccagtc tgcagacgtg ttttgtttgg acttcactta 2450

 aaaaaatgcc ttagttgtta tcatctttgg gagagttcat tcaaaatgtc 2500

 cagcttctct tgaaaacttg gtatatctgg ccacactggg ctcacattcc 2550

 caagggtaac tcttggccag agctgagtgg cagccgcctc ccttatgcag 2600

 gacatgtgct ctcggcttca ccagggttct gaccgggtct gcttctgcat 2650

 tcacagcgcc tcctggacct gaaggcatct gagtgtgaga ccctgttcta 2700

 actcttagaa gtgacattgt aagaggtggt ggggaccagc taattggtcc 2750

 aacccagcct gagtgcacca ccctttgaac aaatgtatca gtgatgaaaa 2800

 tttgcctttg ccccggcttg cctgtaatcc cagcactttg ggaggccgag 2850

 gtgggcggat cacttgaggt cgggagttca agaccagcct ggccaacatg 2900

 gcgaaacccc gtctctacta aacataaaaa aattagtcag gtgtggcggt 2950

 gcgtgcctgt aatcccagct attcaggagg ctgaggcacc agaattgctt 3000

 gaacccagga ggtggaggtt gcagtgaact gagactgcgc cacggcactc 3050

 cagcctgggc gacagagcaa gactctgtct caataaataa ataattaatt 3100

 aaaataaaaa acagcttaaa gagaaaaatg gcctgcaaac cttttttatg 3150

 atgctatttt tattaatata aagtcctgtt tattgagacc ctttaaatgc 3200

 ctgcgagaga ccctacagac agtatgtcta ctcctcacag catctctatg 3250

 aagagaagga gggttgtgcc cacttcatag atgagaaaac tgagaggtga 3300

 ggtgacttgc ctggggccac atagctcata agctgtagaa ctctgcaggc 3350

 agatttactg tcccaggagc aaatgctgga tgagcaactc ctgttctttg 3400

 ggctcaaggg gactggtgat gggacaattc ttctcgactt caggagctga 3450

 cagagccaga ggcacctaaa cttgggtaca tcttgtaaga cacataatga 3500

 ggtccctcta gctttagctg gagggagata aaagaacccc agacctctga 3550

 atgtcccaga ggctagtctc ttctcagagc agcactgggg tttgggggct 3600

 tccctgggcc tcagcctcca ggcaccccca ggattcccag agagacgctg 3650

 tgattggcag gaggcaggat atccccaggg aaacccatct tcacgcctgg 3700

 gtgaccccca ctgccgcctc cttcttaact ctgcaggaaa tcagagctgg 3750

 cagcctccag tgggaggaca gagccggttt ccgtggcaac cctcagctgc 3800

 ctcatcgtgg ctgggaaggg aaggaagcaa gccggcagaa atagctatgg 3850

 aaggtcttgc gcaggctgca accctggtgt gctgggcgaa aacccttatg 3900

 actcccccct tccaaatcag gctgggttgt cactgagact agattctcac 3950

 ctgccttcaa agaagggcca attcccttta aaggtcgcac ctccttggaa 4000

 ccacagtcat tagtgaatta cactcaagga aaagatgtgc tcccaccagg 4050

 cagctccagc tgttacctga gatactgaag tgcagctcag gagacgatta 4100

 tttaaacctg cccttgtttt aatcgttatt tttctcttta aaaaaaatag 4150

 aagctataaa gaaaagaggg agagatgagt gggttagcta cctgctatgc 4200

 gctagttagg aagttacctg gatgccattg tatttcttca tcccttgctt 4250

 aagaatcaaa attactggac atatgttagg aatactcttt ctttctttct 4300

 ttctttttaa gctcagtggc aagaatgaaa tactcttttt tttttttttt 4350

 ttttgagatg gagtctcgct ctgctgccca ggctagagtg cagtggcgtg 4400

 atctcggctc actgcaagct ctgcctcccg tgttcacacc attctcctgc 4450

 ctcagcctcc tgagtagctg ggactacagg cacccgccac cacacccggc 4500

 taatttttgg atttttagta gagatgggat ttcaccgtat tagccaggat 4550

 ggtcttgatc tcctgagctc gtgatctgcc cgcctcggcc tcccaaagtg 4600

 ctgggattac aggtgtgagc caccgcgccc agccaagaat aaaatactct 4650

 taagttgatc taatgaagtg tttccttacc attgtgatta ttgttactat 4700

 tatttgctat attttaatat tgttgtttac caaatattct cctttaaaca 4750

 gactcgcttt ttaaactttt tttttttttt ttgagacgga gtttcacgct 4800

 tattgcccag gctggagtgc aatggcacga tctcagctca ccacaacctc 4850

 cacctcctgg gtttaagcaa tgcttctgcc tcagcttccc aagtagctga 4900

 gattacaggc gcacaccacc acgcccaact gatttttgta tttttagtag 4950

 agacggggtt tccccatgtt ggtcaggctg gtctcgaact cctgacctcg 5000

 tgatttgcct gcctgggcct cccaaagtgc taggattaca ggcatgagcc 5050

 accatgcccg gcctaaactt tgtttttaaa atgaactttt tttcccccca 5100

 attgctgcca atagtggata acatgtatca ctcactgcca aaaatagaaa 5150

 gtgaccatga aaaataaatt cgctggggaa gggggctcca tgctggtgtg 5200

 gccaaggctg agagctctct cttctctgtt acaaaacgag ataagcaagt 5250

 gttagaattg ccttaaggcc acactggcat ctccctgacc ttctccaggg 5300

 acagaagcag gagtaagttt ctcatcccat gggcgaccag ggccatctcc 5350

 tcccaccagt ggcccccact cacagggagc tggcaatgcc ctacctgcct 5400

 gttctccaga tggagaaaca ggctctgaga tttcacaggt cttgcccaaa 5450

 gtcattgatt ttgatgatta aaaagaataa acacagtgtt tcctgagtag 5500

 cagtgattgt tatgccttgc tattttaata aagattctat tttcgtataa 5550

 cattgtcaag tggaaacatg ctgaaatcta ttaaaccatc tttgtttgtg 5600

<210> 1726
<211> 500
<212> PRT
<213> Homo sapien

<400> 1726
 Met Ala Trp Ala Ala Leu Leu Gly Leu Leu Ala Ala Leu Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Ser Arg Arg Arg Thr Arg Arg Pro Gly Glu Pro
                  20                  25                  30

 Pro Leu Asp Leu Gly Ser Ile Pro Trp Leu Gly Tyr Ala Leu Asp
                  35                  40                  45

 Phe Gly Lys Asp Ala Ala Ser Phe Leu Thr Arg Met Lys Glu Lys
                  50                  55                  60

 His Gly Asp Ile Phe Thr Ile Leu Val Gly Gly Arg Tyr Val Thr
                  65                  70                  75

 Val Leu Leu Asp Pro His Ser Tyr Asp Ala Val Val Trp Glu Pro
                  80                  85                  90

 Arg Thr Arg Leu Asp Phe His Ala Tyr Ala Ile Phe Leu Met Glu
                  95                 100                 105

 Arg Ile Phe Asp Val Gln Leu Pro His Tyr Ser Pro Ser Asp Glu
                 110                 115                 120

 Lys Ala Arg Met Lys Leu Thr Leu Leu His Arg Glu Leu Gln Ala
                 125                 130                 135

 Leu Thr Glu Ala Met Tyr Thr Asn Leu His Ala Val Leu Leu Gly
                 140                 145                 150

 Asp Ala Thr Glu Ala Gly Ser Gly Trp His Glu Met Gly Leu Leu
                 155                 160                 165

 Asp Phe Ser Tyr Ser Phe Leu Leu Arg Ala Gly Tyr Leu Thr Leu
                 170                 175                 180

 Tyr Gly Ile Glu Ala Leu Pro Arg Thr His Glu Ser Gln Ala Gln
                 185                 190                 195

 Asp Arg Val His Ser Ala Asp Val Phe His Thr Phe Arg Gln Leu
                 200                 205                 210

 Asp Arg Leu Leu Pro Lys Leu Ala Arg Gly Ser Leu Ser Val Gly
                 215                 220                 225

 Asp Lys Asp His Met Cys Ser Val Lys Ser Arg Leu Trp Lys Leu
                 230                 235                 240

 Leu Ser Pro Ala Arg Leu Ala Arg Arg Ala His Arg Ser Lys Trp
                 245                 250                 255

 Leu Glu Ser Tyr Leu Leu His Leu Glu Glu Met Gly Val Ser Glu
                 260                 265                 270

 Glu Met Gln Ala Arg Ala Leu Val Leu Gln Leu Trp Ala Thr Gln
                 275                 280                 285

 Gly Asn Met Gly Pro Ala Ala Phe Trp Leu Leu Leu Phe Leu Leu
                 290                 295                 300

 Lys Asn Pro Glu Ala Leu Ala Ala Val Arg Gly Glu Leu Glu Ser
                 305                 310                 315

 Ile Leu Trp Gln Ala Glu Gln Pro Val Ser Gln Thr Thr Thr Leu
                 320                 325                 330

 Pro Gln Lys Val Leu Asp Ser Thr Pro Val Leu Asp Ser Val Leu
                 335                 340                 345

 Ser Glu Ser Leu Arg Leu Thr Ala Ala Pro Phe Ile Thr Arg Glu
                 350                 355                 360

 Val Val Val Asp Leu Ala Met Pro Met Ala Asp Gly Arg Glu Phe
                 365                 370                 375

 Asn Leu Arg Arg Gly Asp Arg Leu Leu Leu Phe Pro Phe Leu Ser
                 380                 385                 390

 Pro Gln Arg Asp Pro Glu Ile Tyr Thr Asp Pro Glu Val Phe Lys
                 395                 400                 405

 Tyr Asn Arg Phe Leu Asn Pro Asp Gly Ser Glu Lys Lys Asp Phe
                 410                 415                 420

 Tyr Lys Asp Gly Lys Arg Leu Lys Asn Tyr Asn Met Pro Trp Gly
                 425                 430                 435

 Ala Gly His Asn His Cys Leu Gly Arg Ser Tyr Ala Val Asn Ser
                 440                 445                 450

 Ile Lys Gln Phe Val Phe Leu Val Leu Val His Leu Asp Leu Glu
                 455                 460                 465

 Leu Ile Asn Ala Asp Val Glu Ile Pro Glu Phe Asp Leu Ser Arg
                 470                 475                 480

 Tyr Gly Phe Gly Leu Met Gln Pro Glu His Asp Val Pro Val Arg
                 485                 490                 495

 Tyr Arg Ile Arg Pro
                 500

<210> 1727
<211> 3319
<212> DNA
<213> Homo sapien

<400> 1727
 ctacctcttc ctctccacgc ggttgagaag accggtcggc ctgggcaacc 50

 tgcgctgaag atgccgggaa aactccgtag tgacgctggt ttggaatcag 100

 acaccgcaat gaaaaaaggg gagacactgc gaaagcaaac cgaggagaaa 150

 gagaaaaaaa gagaagccaa aatctgataa gactgaagag atagcagaag 200

 aggaagaaac tgttttcccc aaagctaaac aagttaaaaa gaaagcagag 250

 ccttctgaag ttgacatgaa ttctcctaaa tccaaaaagg caaaaaagaa 300

 agaggagcca tctcaaaatg acatttctcc taaaaccaaa agtttgagaa 350

 agaaaaagga gcccattgaa aagaaagtgg tttcttctaa aaccaaaaaa 400

 gtgacaaaaa atgaggagcc ttctgaggaa gaaatagatg ctcctaagcc 450

 caagaagatg aagaaagaaa aggaaatgaa tggagaaact agagagaaaa 500

 gccccaaact gaagaatgga tttcctcatc ctgaaccgga ctgtaacccc 550

 agtgaagctg ccagtgaaga aagtaacagt gagatagagc aggaaatacc 600

 tgtggaacaa aaagaaggcg ctttctctaa ttttcccata tctgaagaaa 650

 ctattaaact tctcaaaggc cgaggagtga ccttcctatt tcctatacaa 700

 gcaaagacat tccatcatgt ttacagcggg aaggacttaa ttgcacaggc 750

 acggacagga actgggaaga cattctcctt tgccatccct ttgattgaga 800

 aacttcatgg ggaactgcaa gacaggaaga gaggccgtgc ccctcaggta 850

 ctggttcttg cacctacaag agagttggca aatcaagtaa gcaaagactt 900

 cagtgacatc acaaaaaagc tgtcagtggc ttgtttttat ggtggaactc 950

 cctatggagg tcaatttgaa cgcatgagga atgggattga tatcctggtt 1000

 ggaacaccag gtcgtatcaa agaccacata cagaatggca aactagatct 1050

 caccaaactt aagcatgttg tcctggatga agtggaccag atgttggata 1100

 tgggatttgc tgatcaagtg gaagagattt taagtgtggc atacaagaaa 1150

 gattctgaag acaatcccca aacattgctt ttttctgcaa cttgccctca 1200

 ttgggtattt aatgttgcca agaaatacat gaaatctaca tatgaacagg 1250

 tggacctgat tggtaaaaag actcagaaaa cggcaataac tgtggagcat 1300

 ctggctatta agtgccactg gactcagagg gcagcagtta ttggggatgt 1350

 catccgagta tatagtggtc atcaaggacg cactatcatc ttttgtgaaa 1400

 ccaagaaaga agcccaggag ctgtcccaga attcagctat aaagcaggat 1450

 gctcagtcct tgcatggaga cattccacag aagcaaaggg aaatcaccct 1500

 gaaaggtttt agaaatggta gttttggagt tttggtggca accaatgttg 1550

 ctgcacgtgg gttagacatc cctgaggttg atttggttat acaaagctct 1600

 ccaccaaagg atgtagagtc ctacattcat cgatccgggc ggacaggcag 1650

 agctggaagg acgggggtgt gcatctgctt ttatcagcac aaggaagaat 1700

 atcagttagt acaagtggag caaaaagcgg gaattaagtt caaacgaata 1750

 ggtgttcctt ctgcaacaga aataataaaa gcttccagca aagatgccat 1800

 caggcttttg gattccgtgc ctcccactgc cattagtcac ttcaaacaat 1850

 cagctgagaa gctgatagag gagaagggag ctgtggaagc tctggcagca 1900

 gcactggccc atatttcagg tgccacgtcc gtagaccagc gctccttgat 1950

 caactcaaat gtgggttttg tgaccatgat cttgcagtgc tcaattgaaa 2000

 tgccaaatat tagttatgct tggaaagaac ttaaagagca gctgggcgag 2050

 gagattgatt ccaaagtgaa gggaatggtt tttctcaaag gaaagctggg 2100

 tgtttgcttt gatgtaccta ccgcatcagt aacagaaata caggagaaat 2150

 ggcatgattc acgacgctgg cagctctctg tggccacaga gcaaccagaa 2200

 ctggaaggac cacgggaagg atatggaggc ttcaggggac agcgggaagg 2250

 cagtcgaggc ttcaggggac agcgggacgg aaacagaaga ttcagaggac 2300

 agcgggaagg cagtagaggc ccgagaggac agcgatcagg aggtggcaac 2350

 aaaagtaaca gatcccaaaa caaaggccag aagcggagtt tcagtaaagc 2400

 atttggtcaa taattagaaa tagaagattt atatagcaaa aagagaatga 2450

 tgtttggcaa tatagaactg aacattattt ttcatgcaaa gttaaaagca 2500

 cattgtgcct ccttttgacc acttgccaag tccctgtctc tttcagacac 2550

 agacaagctt catttaaatt atttcatctg atcattatca tttataactt 2600

 tattgttact tcatcagttt ttccttttga aaggtgtatg aattcattac 2650

 atttttattc taatgtatta tctgtagatt agaagataaa atcaagcatg 2700

 tatctgccta tactttgtga gttcacctgt ctttatactc aaaagtgtcc 2750

 cttaatagtg tccttccctg aaataaatac ctaagggagt gtaacagtct 2800

 ctggaggacc actttgagcc tttggaagtt aaggtttcct cagccacctg 2850

 ccgaacagtt tctcatgtgg tcctattatt tgtctactga gacttaatac 2900

 tgagcaatgt tttgaaacaa gatttcaaac taatctgggt tgtaatacag 2950

 tttataccag tgtatgctct agacttggaa gatgtagtat gtttgatgtg 3000

 gattacctat acttatgttc gttttgatac atttttagct tctcattata 3050

 aggtgattca tgctttagtg aattcttcat agatagtata tataaaagta 3100

 cattttaata gaaagccagg gttttaagga atttcacatg tataaggtgg 3150

 ctccatagct ttatttgtaa gtaggctgga taaatggtgc ttaaatggta 3200

 atgtactcca cttcttccta ttggaagatt aacattattt accaagaagg 3250

 acttaaggga gtaaggggcg cagattagca ttgctcaaga gtatgtaaaa 3300

 aaaaaaaaaa aaaaaaaaa 3319

<210> 1728
<211> 715
<212> PRT
<213> Homo sapien

<400> 1728
 Met Asn Ser Pro Lys Ser Lys Lys Ala Lys Lys Lys Glu Glu Pro
   1               5                  10                  15

 Ser Gln Asn Asp Ile Ser Pro Lys Thr Lys Ser Leu Arg Lys Lys
                  20                  25                  30

 Lys Glu Pro Ile Glu Lys Lys Val Val Ser Ser Lys Thr Lys Lys
                  35                  40                  45

 Val Thr Lys Asn Glu Glu Pro Ser Glu Glu Glu Ile Asp Ala Pro
                  50                  55                  60

 Lys Pro Lys Lys Met Lys Lys Glu Lys Glu Met Asn Gly Glu Thr
                  65                  70                  75

 Arg Glu Lys Ser Pro Lys Leu Lys Asn Gly Phe Pro His Pro Glu
                  80                  85                  90

 Pro Asp Cys Asn Pro Ser Glu Ala Ala Ser Glu Glu Ser Asn Ser
                  95                 100                 105

 Glu Ile Glu Gln Glu Ile Pro Val Glu Gln Lys Glu Gly Ala Phe
                 110                 115                 120

 Ser Asn Phe Pro Ile Ser Glu Glu Thr Ile Lys Leu Leu Lys Gly
                 125                 130                 135

 Arg Gly Val Thr Phe Leu Phe Pro Ile Gln Ala Lys Thr Phe His
                 140                 145                 150

 His Val Tyr Ser Gly Lys Asp Leu Ile Ala Gln Ala Arg Thr Gly
                 155                 160                 165

 Thr Gly Lys Thr Phe Ser Phe Ala Ile Pro Leu Ile Glu Lys Leu
                 170                 175                 180

 His Gly Glu Leu Gln Asp Arg Lys Arg Gly Arg Ala Pro Gln Val
                 185                 190                 195

 Leu Val Leu Ala Pro Thr Arg Glu Leu Ala Asn Gln Val Ser Lys
                 200                 205                 210

 Asp Phe Ser Asp Ile Thr Lys Lys Leu Ser Val Ala Cys Phe Tyr
                 215                 220                 225

 Gly Gly Thr Pro Tyr Gly Gly Gln Phe Glu Arg Met Arg Asn Gly
                 230                 235                 240

 Ile Asp Ile Leu Val Gly Thr Pro Gly Arg Ile Lys Asp His Ile
                 245                 250                 255

 Gln Asn Gly Lys Leu Asp Leu Thr Lys Leu Lys His Val Val Leu
                 260                 265                 270

 Asp Glu Val Asp Gln Met Leu Asp Met Gly Phe Ala Asp Gln Val
                 275                 280                 285

 Glu Glu Ile Leu Ser Val Ala Tyr Lys Lys Asp Ser Glu Asp Asn
                 290                 295                 300

 Pro Gln Thr Leu Leu Phe Ser Ala Thr Cys Pro His Trp Val Phe
                 305                 310                 315

 Asn Val Ala Lys Lys Tyr Met Lys Ser Thr Tyr Glu Gln Val Asp
                 320                 325                 330

 Leu Ile Gly Lys Lys Thr Gln Lys Thr Ala Ile Thr Val Glu His
                 335                 340                 345

 Leu Ala Ile Lys Cys His Trp Thr Gln Arg Ala Ala Val Ile Gly
                 350                 355                 360

 Asp Val Ile Arg Val Tyr Ser Gly His Gln Gly Arg Thr Ile Ile
                 365                 370                 375

 Phe Cys Glu Thr Lys Lys Glu Ala Gln Glu Leu Ser Gln Asn Ser
                 380                 385                 390

 Ala Ile Lys Gln Asp Ala Gln Ser Leu His Gly Asp Ile Pro Gln
                 395                 400                 405

 Lys Gln Arg Glu Ile Thr Leu Lys Gly Phe Arg Asn Gly Ser Phe
                 410                 415                 420

 Gly Val Leu Val Ala Thr Asn Val Ala Ala Arg Gly Leu Asp Ile
                 425                 430                 435

 Pro Glu Val Asp Leu Val Ile Gln Ser Ser Pro Pro Lys Asp Val
                 440                 445                 450

 Glu Ser Tyr Ile His Arg Ser Gly Arg Thr Gly Arg Ala Gly Arg
                 455                 460                 465

 Thr Gly Val Cys Ile Cys Phe Tyr Gln His Lys Glu Glu Tyr Gln
                 470                 475                 480

 Leu Val Gln Val Glu Gln Lys Ala Gly Ile Lys Phe Lys Arg Ile
                 485                 490                 495

 Gly Val Pro Ser Ala Thr Glu Ile Ile Lys Ala Ser Ser Lys Asp
                 500                 505                 510

 Ala Ile Arg Leu Leu Asp Ser Val Pro Pro Thr Ala Ile Ser His
                 515                 520                 525

 Phe Lys Gln Ser Ala Glu Lys Leu Ile Glu Glu Lys Gly Ala Val
                 530                 535                 540

 Glu Ala Leu Ala Ala Ala Leu Ala His Ile Ser Gly Ala Thr Ser
                 545                 550                 555

 Val Asp Gln Arg Ser Leu Ile Asn Ser Asn Val Gly Phe Val Thr
                 560                 565                 570

 Met Ile Leu Gln Cys Ser Ile Glu Met Pro Asn Ile Ser Tyr Ala
                 575                 580                 585

 Trp Lys Glu Leu Lys Glu Gln Leu Gly Glu Glu Ile Asp Ser Lys
                 590                 595                 600

 Val Lys Gly Met Val Phe Leu Lys Gly Lys Leu Gly Val Cys Phe
                 605                 610                 615

 Asp Val Pro Thr Ala Ser Val Thr Glu Ile Gln Glu Lys Trp His
                 620                 625                 630

 Asp Ser Arg Arg Trp Gln Leu Ser Val Ala Thr Glu Gln Pro Glu
                 635                 640                 645

 Leu Glu Gly Pro Arg Glu Gly Tyr Gly Gly Phe Arg Gly Gln Arg
                 650                 655                 660

 Glu Gly Ser Arg Gly Phe Arg Gly Gln Arg Asp Gly Asn Arg Arg
                 665                 670                 675

 Phe Arg Gly Gln Arg Glu Gly Ser Arg Gly Pro Arg Gly Gln Arg
                 680                 685                 690

 Ser Gly Gly Gly Asn Lys Ser Asn Arg Ser Gln Asn Lys Gly Gln
                 695                 700                 705

 Lys Arg Ser Phe Ser Lys Ala Phe Gly Gln
                 710                 715

<210> 1729
<211> 2171
<212> DNA
<213> Homo sapien

<400> 1729
 agcagctctg taatgcgctt gtggtttcag atgtgggcgg cctgtgtgaa 50

 cctgtcgtgc aaagctcacg tcaccaactg ctgcagttat ctcctgaatc 100

 aggctgaggg tctttgctgt gcacccagag atagttgggt gacaaatcac 150

 ctccaggttg gggatgcctc agacttgtga tgggactggg cagatgcatc 200

 tgggaaggct ggaccttgga gagtgaggcc ctgaggcgag acatgggcac 250

 ctggctcctg gcctgcatct gcatctgcac ctgtgtctgc ttgggagtct 300

 ctgtcacagg ggaaggacaa gggccaaggt ctagaacctt cacctgcctc 350

 accaacaaca ttctcaggat cgattgccac tggtctgccc cagagctggg 400

 acagggctcc agcccctggc tcctcttcac cagcaaccag gctcctggcg 450

 gcacacataa gtgcatcttg cggggcagtg agtgcaccgt cgtgctgcca 500

 cctgaggcag tgctcgtgcc atctgacaat ttcaccatca ctttccacca 550

 ctgcatgtct gggagggagc aggtcagcct ggtggacccg gagtacctgc 600

 cccggagaca cgttaagctg gacccgccct ctgacttgca gagcaacatc 650

 agttctggcc actgcatcct gacctggagc atcagtcctg ccttggagcc 700

 aatgaccaca cttctcagct atgagctggc cttcaagaag caggaagagg 750

 cctgggagca ggcccagcac agggatcaca ttgtcggggt gacctggctt 800

 atacttgaag cctttgagct ggaccctggc tttatccatg aggccaggct 850

 gcgtgtccag atggccacac tggaggatga tgtggtagag gaggagcgtt 900

 atacaggcca gtggagtgag tggagccagc ctgtgtgctt ccaggctccc 950

 cagagacaag gccctctgat cccaccctgg gggtggccag gcaacaccct 1000

 tgttgctgtg tccatctttc tcctgctgac tggcccgacc tacctcctgt 1050

 tcaagctgtc gcccagggtg aagagaatct tctaccagaa cgtgccctct 1100

 ccagcgatgt tcttccagcc cctctacagt gtacacaatg ggaacttcca 1150

 gacttggatg ggggcccacg gggccggtgt gctgttgagc caggactgtg 1200

 ctggcacccc acagggagcc ttggagccct gcgtccagga ggccactgca 1250

 ctgctcactt gtggcccagc gcgtccttgg aaatctgtgg ccctggagga 1300

 ggaacaggag ggccctggga ccaggctccc ggggaacctg agctcagagg 1350

 atgtgctgcc agcagggtgt acggagtgga gggtacagac gcttgcctat 1400

 ctgccacagg aggactgggc ccccacgtcc ctgactaggc cggctccccc 1450

 agactcagag ggcagcagga gcagcagcag cagcagcagc agcaacaaca 1500

 acaactactg tgccttgggc tgctatgggg gatggcacct ctcagccctc 1550

 ccaggaaaca cacagagctc tgggcccatc ccagccctgg cctgtggcct 1600

 ttcttgtgac catcagggcc tggagaccca gcaaggagtt gcctgggtgc 1650

 tggctggtca ctgccagagg cctgggctgc atgaggacct ccagggcatg 1700

 ttgctccctt ctgtcctcag caaggctcgg tcctggacat tctaggtccc 1750

 tgactcgcca gatgcatcat gtccattttg ggaaaatgga ctgaagtttc 1800

 tggagccctt gtctgagact gaacctcctg agaaggggcc cctagcagcg 1850

 gtcagaggtc ctgtctggat ggaggctgga ggctcccccc tcaacccctc 1900

 tgctcagtgc ctgtggggag cagcctctac cctcagcatc ctggccacaa 1950

 gttcttcctt ccattgtccc ttttctttat ccctgacctc tctgagaagt 2000

 ggggtgtggt ctctcagctg ttctgccctc atacccttaa agggccagcc 2050

 tgggcccagt ggacacaggt aaggcaccat gaccacctgg tgtgacctct 2100

 ctgtgcctta ctgaggcacc tttctagaga ttaaaagggg cttgatggct 2150

 gttaaaaaaa aaaaaaaaaa a 2171

<210> 1730
<211> 521
<212> PRT
<213> Homo sapien

<400> 1730
 Met Gly Leu Gly Arg Cys Ile Trp Glu Gly Trp Thr Leu Glu Ser
   1               5                  10                  15

 Glu Ala Leu Arg Arg Asp Met Gly Thr Trp Leu Leu Ala Cys Ile
                  20                  25                  30

 Cys Ile Cys Thr Cys Val Cys Leu Gly Val Ser Val Thr Gly Glu
                  35                  40                  45

 Gly Gln Gly Pro Arg Ser Arg Thr Phe Thr Cys Leu Thr Asn Asn
                  50                  55                  60

 Ile Leu Arg Ile Asp Cys His Trp Ser Ala Pro Glu Leu Gly Gln
                  65                  70                  75

 Gly Ser Ser Pro Trp Leu Leu Phe Thr Ser Asn Gln Ala Pro Gly
                  80                  85                  90

 Gly Thr His Lys Cys Ile Leu Arg Gly Ser Glu Cys Thr Val Val
                  95                 100                 105

 Leu Pro Pro Glu Ala Val Leu Val Pro Ser Asp Asn Phe Thr Ile
                 110                 115                 120

 Thr Phe His His Cys Met Ser Gly Arg Glu Gln Val Ser Leu Val
                 125                 130                 135

 Asp Pro Glu Tyr Leu Pro Arg Arg His Val Lys Leu Asp Pro Pro
                 140                 145                 150

 Ser Asp Leu Gln Ser Asn Ile Ser Ser Gly His Cys Ile Leu Thr
                 155                 160                 165

 Trp Ser Ile Ser Pro Ala Leu Glu Pro Met Thr Thr Leu Leu Ser
                 170                 175                 180

 Tyr Glu Leu Ala Phe Lys Lys Gln Glu Glu Ala Trp Glu Gln Ala
                 185                 190                 195

 Gln His Arg Asp His Ile Val Gly Val Thr Trp Leu Ile Leu Glu
                 200                 205                 210

 Ala Phe Glu Leu Asp Pro Gly Phe Ile His Glu Ala Arg Leu Arg
                 215                 220                 225

 Val Gln Met Ala Thr Leu Glu Asp Asp Val Val Glu Glu Glu Arg
                 230                 235                 240

 Tyr Thr Gly Gln Trp Ser Glu Trp Ser Gln Pro Val Cys Phe Gln
                 245                 250                 255

 Ala Pro Gln Arg Gln Gly Pro Leu Ile Pro Pro Trp Gly Trp Pro
                 260                 265                 270

 Gly Asn Thr Leu Val Ala Val Ser Ile Phe Leu Leu Leu Thr Gly
                 275                 280                 285

 Pro Thr Tyr Leu Leu Phe Lys Leu Ser Pro Arg Val Lys Arg Ile
                 290                 295                 300

 Phe Tyr Gln Asn Val Pro Ser Pro Ala Met Phe Phe Gln Pro Leu
                 305                 310                 315

 Tyr Ser Val His Asn Gly Asn Phe Gln Thr Trp Met Gly Ala His
                 320                 325                 330

 Gly Ala Gly Val Leu Leu Ser Gln Asp Cys Ala Gly Thr Pro Gln
                 335                 340                 345

 Gly Ala Leu Glu Pro Cys Val Gln Glu Ala Thr Ala Leu Leu Thr
                 350                 355                 360

 Cys Gly Pro Ala Arg Pro Trp Lys Ser Val Ala Leu Glu Glu Glu
                 365                 370                 375

 Gln Glu Gly Pro Gly Thr Arg Leu Pro Gly Asn Leu Ser Ser Glu
                 380                 385                 390

 Asp Val Leu Pro Ala Gly Cys Thr Glu Trp Arg Val Gln Thr Leu
                 395                 400                 405

 Ala Tyr Leu Pro Gln Glu Asp Trp Ala Pro Thr Ser Leu Thr Arg
                 410                 415                 420

 Pro Ala Pro Pro Asp Ser Glu Gly Ser Arg Ser Ser Ser Ser Ser
                 425                 430                 435

 Ser Ser Ser Asn Asn Asn Asn Tyr Cys Ala Leu Gly Cys Tyr Gly
                 440                 445                 450

 Gly Trp His Leu Ser Ala Leu Pro Gly Asn Thr Gln Ser Ser Gly
                 455                 460                 465

 Pro Ile Pro Ala Leu Ala Cys Gly Leu Ser Cys Asp His Gln Gly
                 470                 475                 480

 Leu Glu Thr Gln Gln Gly Val Ala Trp Val Leu Ala Gly His Cys
                 485                 490                 495

 Gln Arg Pro Gly Leu His Glu Asp Leu Gln Gly Met Leu Leu Pro
                 500                 505                 510

 Ser Val Leu Ser Lys Ala Arg Ser Trp Thr Phe
                 515                 520

<210> 1731
<211> 1880
<212> DNA
<213> Homo sapien

<400> 1731
 atgcaacagg acggacttgg agtagggaca aggaacggaa gtgggaaggg 50

 gaggagcgtg cacccctcct ggccttggtg cgcgccgcgc cccctaaggt 100

 actttggaag ggacgcgcgg gccagacgcg cccagacggc cgcgatggcg 150

 ctggccatcc aggtgaccgt gtccaacccc taccacgtgg tgatcctctt 200

 ccagcctgtg accctgccct gtacctacca gatgacctcg acccccacgc 250

 aacccatcgt catctggaag tacaagtctt tctgccggga ccgcatcgcc 300

 gatgccttct ccccggccag cgtcgacaac cagctcaatg cccagctggc 350

 agccgggaac ccaggctaca acccctacgt tgagtgccag gacagcgtgc 400

 gcaccgtcag ggtcgtggcc accaagcagg gcaacgctgt gaccctggga 450

 gattactacc agggccggag gattaccatc accggaaatg ctgacctgac 500

 ctttgaccag acggcgtggg gggacagtgg tgtgtattac tgctccgtgg 550

 tctcagccca ggacctccag gggaacaatg aggcctacgc agagctcatc 600

 gtccttggga ggacctcagg ggtggctgag ctcttacctg gttttcaggc 650

 ggggcccata gaagactggc tcttcgtggt tgtggtatgc ctggctgcct 700

 tcctcatctt cctcctcctg ggcatctgct ggtgccagtg ctgcccgcac 750

 acttgctgct gctacgtcag gtgcccctgc tgcccagaca agtgctgctg 800

 ccccgaggcc ctgtatgccg ccggcaaagc agccacctca ggtgttccca 850

 gcatttatgc ccccagcacc tatgcccacc tgtctcccgc caagacccca 900

 cccccaccag ctatgattcc catgggccct gcctacaacg ggtaccctgg 950

 aggataccct ggagacgttg acaggagtag ctcagtccgc agtggctaca 1000

 ggattcaggc cagccagcag gacgactcca tgcgggtcct gtactacatg 1050

 gagaaggagc tggccaactt cgacccttct cgacctggcc cccccagtgg 1100

 ccgtgtggag cgggccatga gtgaagtcac ctccctccac gaggacgact 1150

 ggcgatctcg gccttcccgg ggccctgccc tcaccccgat ccgggatgag 1200

 gagtggggtg gccactcccc ccggagtccc aggggatggg accaggagcc 1250

 cgccagggag caggcaggcg ggggctggcg ggccaggcgg ccccgggccc 1300

 gctccgtgga cgccctggac gacctcaccc cgccgagcac cgccgagtca 1350

 gggagcaggt ctcccacgag taatggtggg agaagccggg cctacatgcc 1400

 cccgcggagc cgcagccggg acgacctcta tgaccaagac gactcgaggg 1450

 acttcccacg ctcccgggac ccccactacg acgacttcag gtctcgggag 1500

 cgccctcctg ccgaccccag gtcccaccac caccgtaccc gggaccctcg 1550

 ggacaacggc tccaggtccg gggacctccc ctatgatggg cggctactgg 1600

 aggaggctgt gaggaagaag gggtcggagg agaggaggag accccacaag 1650

 gaggaggagg aagaggccta ctacccgccc gcgccgcccc cgtactcgga 1700

 gaccgactcg caggcgtccc gagagcgcag gctcaagaag aacttggccc 1750

 tgagtcggga aagtttagtc gtctgatctg acgttttcta cgtagctttt 1800

 gtattttttt ttttaatttg aaggaacact gatgaagccc tgccataccc 1850

 ctcccgagtc taataaaacg tataatcaca 1880

<210> 1732
<211> 591
<212> PRT
<213> Homo sapien

<400> 1732
 Met Gln Gln Asp Gly Leu Gly Val Gly Thr Arg Asn Gly Ser Gly
   1               5                  10                  15

 Lys Gly Arg Ser Val His Pro Ser Trp Pro Trp Cys Ala Pro Arg
                  20                  25                  30

 Pro Leu Arg Tyr Phe Gly Arg Asp Ala Arg Ala Arg Arg Ala Gln
                  35                  40                  45

 Thr Ala Ala Met Ala Leu Ala Ile Gln Val Thr Val Ser Asn Pro
                  50                  55                  60

 Tyr His Val Val Ile Leu Phe Gln Pro Val Thr Leu Pro Cys Thr
                  65                  70                  75

 Tyr Gln Met Thr Ser Thr Pro Thr Gln Pro Ile Val Ile Trp Lys
                  80                  85                  90

 Tyr Lys Ser Phe Cys Arg Asp Arg Ile Ala Asp Ala Phe Ser Pro
                  95                 100                 105

 Ala Ser Val Asp Asn Gln Leu Asn Ala Gln Leu Ala Ala Gly Asn
                 110                 115                 120

 Pro Gly Tyr Asn Pro Tyr Val Glu Cys Gln Asp Ser Val Arg Thr
                 125                 130                 135

 Val Arg Val Val Ala Thr Lys Gln Gly Asn Ala Val Thr Leu Gly
                 140                 145                 150

 Asp Tyr Tyr Gln Gly Arg Arg Ile Thr Ile Thr Gly Asn Ala Asp
                 155                 160                 165

 Leu Thr Phe Asp Gln Thr Ala Trp Gly Asp Ser Gly Val Tyr Tyr
                 170                 175                 180

 Cys Ser Val Val Ser Ala Gln Asp Leu Gln Gly Asn Asn Glu Ala
                 185                 190                 195

 Tyr Ala Glu Leu Ile Val Leu Gly Arg Thr Ser Gly Val Ala Glu
                 200                 205                 210

 Leu Leu Pro Gly Phe Gln Ala Gly Pro Ile Glu Asp Trp Leu Phe
                 215                 220                 225

 Val Val Val Val Cys Leu Ala Ala Phe Leu Ile Phe Leu Leu Leu
                 230                 235                 240

 Gly Ile Cys Trp Cys Gln Cys Cys Pro His Thr Cys Cys Cys Tyr
                 245                 250                 255

 Val Arg Cys Pro Cys Cys Pro Asp Lys Cys Cys Cys Pro Glu Ala
                 260                 265                 270

 Leu Tyr Ala Ala Gly Lys Ala Ala Thr Ser Gly Val Pro Ser Ile
                 275                 280                 285

 Tyr Ala Pro Ser Thr Tyr Ala His Leu Ser Pro Ala Lys Thr Pro
                 290                 295                 300

 Pro Pro Pro Ala Met Ile Pro Met Gly Pro Ala Tyr Asn Gly Tyr
                 305                 310                 315

 Pro Gly Gly Tyr Pro Gly Asp Val Asp Arg Ser Ser Ser Val Arg
                 320                 325                 330

 Ser Gly Tyr Arg Ile Gln Ala Ser Gln Gln Asp Asp Ser Met Arg
                 335                 340                 345

 Val Leu Tyr Tyr Met Glu Lys Glu Leu Ala Asn Phe Asp Pro Ser
                 350                 355                 360

 Arg Pro Gly Pro Pro Ser Gly Arg Val Glu Arg Ala Met Ser Glu
                 365                 370                 375

 Val Thr Ser Leu His Glu Asp Asp Trp Arg Ser Arg Pro Ser Arg
                 380                 385                 390

 Gly Pro Ala Leu Thr Pro Ile Arg Asp Glu Glu Trp Gly Gly His
                 395                 400                 405

 Ser Pro Arg Ser Pro Arg Gly Trp Asp Gln Glu Pro Ala Arg Glu
                 410                 415                 420

 Gln Ala Gly Gly Gly Trp Arg Ala Arg Arg Pro Arg Ala Arg Ser
                 425                 430                 435

 Val Asp Ala Leu Asp Asp Leu Thr Pro Pro Ser Thr Ala Glu Ser
                 440                 445                 450

 Gly Ser Arg Ser Pro Thr Ser Asn Gly Gly Arg Ser Arg Ala Tyr
                 455                 460                 465

 Met Pro Pro Arg Ser Arg Ser Arg Asp Asp Leu Tyr Asp Gln Asp
                 470                 475                 480

 Asp Ser Arg Asp Phe Pro Arg Ser Arg Asp Pro His Tyr Asp Asp
                 485                 490                 495

 Phe Arg Ser Arg Glu Arg Pro Pro Ala Asp Pro Arg Ser His His
                 500                 505                 510

 His Arg Thr Arg Asp Pro Arg Asp Asn Gly Ser Arg Ser Gly Asp
                 515                 520                 525

 Leu Pro Tyr Asp Gly Arg Leu Leu Glu Glu Ala Val Arg Lys Lys
                 530                 535                 540

 Gly Ser Glu Glu Arg Arg Arg Pro His Lys Glu Glu Glu Glu Glu
                 545                 550                 555

 Ala Tyr Tyr Pro Pro Ala Pro Pro Pro Tyr Ser Glu Thr Asp Ser
                 560                 565                 570

 Gln Ala Ser Arg Glu Arg Arg Leu Lys Lys Asn Leu Ala Leu Ser
                 575                 580                 585

 Arg Glu Ser Leu Val Val
                 590

<210> 1733
<211> 591
<212> DNA
<213> Homo sapien

<400> 1733
 ccgctgtcaa gatgcttctg gccatggtcc ttacctctgc cctgctcctg 50

 tgctccgtgg caggccaggg gtgtccaacc ttggcgggga tcctggacat 100

 caacttcctc atcaacaaga tgcaggaaga tccagcttcc aagtgccact 150

 gcagtgctaa tgtgaccagt tgtctctgtt tgggcattcc ctctgacaac 200

 tgcaccagac catgcttcag tgagagactg tctcagatga ccaataccac 250

 catgcaaaca agatacccac tgattttcag tcgggtgaaa aaatcagttg 300

 aagtactaaa gaacaacaag tgtccatatt tttcctgtga acagccatgc 350

 aaccaaacca cggcaggcaa cgcgctgaca tttctgaaga gtcttctgga 400

 aattttccag aaagaaaaga tgagagggat gagaggcaag atatgaagat 450

 gaaatattat ttatcctatt tattaaattt aaaaagcttt ctctttaagt 500

 tgctacaatt taaaaatcaa gtaagctact ctaaatcagt atcagttgtg 550

 attatttgtt taacattgta tgtctttatt ttgaaataaa t 591

<210> 1734
<211> 144
<212> PRT
<213> Homo sapien

<400> 1734
 Met Leu Leu Ala Met Val Leu Thr Ser Ala Leu Leu Leu Cys Ser
   1               5                  10                  15

 Val Ala Gly Gln Gly Cys Pro Thr Leu Ala Gly Ile Leu Asp Ile
                  20                  25                  30

 Asn Phe Leu Ile Asn Lys Met Gln Glu Asp Pro Ala Ser Lys Cys
                  35                  40                  45

 His Cys Ser Ala Asn Val Thr Ser Cys Leu Cys Leu Gly Ile Pro
                  50                  55                  60

 Ser Asp Asn Cys Thr Arg Pro Cys Phe Ser Glu Arg Leu Ser Gln
                  65                  70                  75

 Met Thr Asn Thr Thr Met Gln Thr Arg Tyr Pro Leu Ile Phe Ser
                  80                  85                  90

 Arg Val Lys Lys Ser Val Glu Val Leu Lys Asn Asn Lys Cys Pro
                  95                 100                 105

 Tyr Phe Ser Cys Glu Gln Pro Cys Asn Gln Thr Thr Ala Gly Asn
                 110                 115                 120

 Ala Leu Thr Phe Leu Lys Ser Leu Leu Glu Ile Phe Gln Lys Glu
                 125                 130                 135

 Lys Met Arg Gly Met Arg Gly Lys Ile
                 140

<210> 1735
<211> 2416
<212> DNA
<213> Homo sapien

<400> 1735
 cgatttcatt cctcgctccc cacaggtccc tctccccaaa atattcccat 50

 cttgtcctag cccatccccc agactatctc aaggaccagc tgtccccacg 100

 cccccgacct ccactaggcc tgtgccaccc gctgcctgca ggaagacgcc 150

 cggtcccggg ccgggttagc cccatgggaa cgcagcgcct gtgtggccgc 200

 gggactcaag gctggcctgg ctcaagtgaa cagcacgtcc aggaggcgac 250

 ctcgtccgcg ggtttgcatt ctggggtgga cgagctgggg gttcggtccg 300

 agcccggtgg gaggctcccg gagcgcagcc tgggcccagc ccaccccgcg 350

 ccggcggcca tggcaggcac cctggacctg gacaagggct gcacggtgga 400

 ggagctgctc cgcgggtgca tcgaagcctt cgatgactcc gggaaggtgc 450

 gggacccgca gctggtgcgc atgttcctca tgatgcaccc ctggtacatc 500

 ccctcctctc agctggcggc caagctgctc cacatctacc aacaatcccg 550

 gaaggacaac tccaattccc tgcaggtgaa aacgtgccac ctggtcaggt 600

 actggatctc cgccttccca gcggagtttg acttgaaccc ggagttggct 650

 gagcagatca aggagctgaa ggctctgcta gaccaagaag ggaaccgacg 700

 gcacagcagc ctaatcgaca tagacagcgt ccctacctac aagtggaagc 750

 ggcaggtgac tcagcggaac cctgtgggac agaaaaagcg caagatgtcc 800

 ctgttgtttg accacctgga gcccatggag ctggcggagc atctcaccta 850

 cttggagtat cgctccttct gcaagatcct gtttcaggac tatcacagtt 900

 tcgtgactca tggctgcact gtggacaacc ccgtcctgga gcggttcatc 950

 tccctcttca acagcgtctc acagtgggtg cagctcatga tcctcagcaa 1000

 acccacagcc ccgcagcggg ccctggtcat cacacacttt gtccacgtgg 1050

 cggagaagct gctacagctg cagaacttca acacgctgat ggcagtggtc 1100

 gggggcctga gccacagctc catctcccgc ctcaaggaga cccacagcca 1150

 cgttagccct gagaccatca agctctggga gggtctcacg gaactagtga 1200

 cggcgacagg caactatggc aactaccggc gtcggctggc agcctgtgtg 1250

 ggcttccgct tcccgatcct gggtgtgcac ctcaaggacc tggtggccct 1300

 gcagctggca ctgcctgact ggctggaccc agcccggacc cggctcaacg 1350

 gggccaagat gaagcagctc tttagcatcc tggaggagct ggccatggtg 1400

 accagcctgc ggccaccagt acaggccaac cccgacctgc tgagcctgct 1450

 cacggtgtct ctggatcagt atcagacgga ggatgagctg taccagctgt 1500

 ccctgcagcg ggagccgcgc tccaagtcct cgccaaccag ccccacgagt 1550

 tgcaccccac caccccggcc cccggtactg gaggagtgga cctcggctgc 1600

 caaacccaag ctggatcagg ccctcgtggt ggagcacatc gagaagatgg 1650

 tggagtctgt gttccggaac tttgacgtcg atggggatgg ccacatctca 1700

 caggaagaat tccagatcat ccgtgggaac ttcccttacc tcagcgcctt 1750

 tggggacctc gaccagaacc aggatggctg catcagcagg gaggagatgg 1800

 tttcctattt cctgcgctcc agctctgtgt tgggggggcg catgggcttc 1850

 gtacacaact tccaggagag caactccttg cgccccgtcg cctgccgcca 1900

 ctgcaaagcc ctgatcctgg gcatctacaa gcagggcctc aaatgccgag 1950

 cctgtggagt gaactgccac aagcagtgca aggatcgcct gtcagttgag 2000

 tgtcggcgca gggcccagag tgtgagcctg gaggggtctg caccctcacc 2050

 ctcacccatg cacagccacc atcaccgcgc cttcagcttc tctctgcccc 2100

 gccctggcag gcgaggctcc aggcctccag agatccgtga ggaggaggta 2150

 cagacggtgg aggatggggt gtttgacatc cacttgtaat agatgctgtg 2200

 gttggatcaa ggactcattc ctgccttgga gaaaatactt caaccagagc 2250

 agggagcctg ggggtgtcgg ggcaggaggc tggggatggg ggtgggatat 2300

 gagggtggca tgcagctgag ggcagggcca gggctggtgt ccctaaggtt 2350

 gtacagactc ttgtgaatat ttgtattttc cagatggaat aaaaaggccc 2400

 gtgtaattaa ccttca 2416

<210> 1736
<211> 671
<212> PRT
<213> Homo sapien

<400> 1736
 Met Gly Thr Gln Arg Leu Cys Gly Arg Gly Thr Gln Gly Trp Pro
   1               5                  10                  15

 Gly Ser Ser Glu Gln His Val Gln Glu Ala Thr Ser Ser Ala Gly
                  20                  25                  30

 Leu His Ser Gly Val Asp Glu Leu Gly Val Arg Ser Glu Pro Gly
                  35                  40                  45

 Gly Arg Leu Pro Glu Arg Ser Leu Gly Pro Ala His Pro Ala Pro
                  50                  55                  60

 Ala Ala Met Ala Gly Thr Leu Asp Leu Asp Lys Gly Cys Thr Val
                  65                  70                  75

 Glu Glu Leu Leu Arg Gly Cys Ile Glu Ala Phe Asp Asp Ser Gly
                  80                  85                  90

 Lys Val Arg Asp Pro Gln Leu Val Arg Met Phe Leu Met Met His
                  95                 100                 105

 Pro Trp Tyr Ile Pro Ser Ser Gln Leu Ala Ala Lys Leu Leu His
                 110                 115                 120

 Ile Tyr Gln Gln Ser Arg Lys Asp Asn Ser Asn Ser Leu Gln Val
                 125                 130                 135

 Lys Thr Cys His Leu Val Arg Tyr Trp Ile Ser Ala Phe Pro Ala
                 140                 145                 150

 Glu Phe Asp Leu Asn Pro Glu Leu Ala Glu Gln Ile Lys Glu Leu
                 155                 160                 165

 Lys Ala Leu Leu Asp Gln Glu Gly Asn Arg Arg His Ser Ser Leu
                 170                 175                 180

 Ile Asp Ile Asp Ser Val Pro Thr Tyr Lys Trp Lys Arg Gln Val
                 185                 190                 195

 Thr Gln Arg Asn Pro Val Gly Gln Lys Lys Arg Lys Met Ser Leu
                 200                 205                 210

 Leu Phe Asp His Leu Glu Pro Met Glu Leu Ala Glu His Leu Thr
                 215                 220                 225

 Tyr Leu Glu Tyr Arg Ser Phe Cys Lys Ile Leu Phe Gln Asp Tyr
                 230                 235                 240

 His Ser Phe Val Thr His Gly Cys Thr Val Asp Asn Pro Val Leu
                 245                 250                 255

 Glu Arg Phe Ile Ser Leu Phe Asn Ser Val Ser Gln Trp Val Gln
                 260                 265                 270

 Leu Met Ile Leu Ser Lys Pro Thr Ala Pro Gln Arg Ala Leu Val
                 275                 280                 285

 Ile Thr His Phe Val His Val Ala Glu Lys Leu Leu Gln Leu Gln
                 290                 295                 300

 Asn Phe Asn Thr Leu Met Ala Val Val Gly Gly Leu Ser His Ser
                 305                 310                 315

 Ser Ile Ser Arg Leu Lys Glu Thr His Ser His Val Ser Pro Glu
                 320                 325                 330

 Thr Ile Lys Leu Trp Glu Gly Leu Thr Glu Leu Val Thr Ala Thr
                 335                 340                 345

 Gly Asn Tyr Gly Asn Tyr Arg Arg Arg Leu Ala Ala Cys Val Gly
                 350                 355                 360

 Phe Arg Phe Pro Ile Leu Gly Val His Leu Lys Asp Leu Val Ala
                 365                 370                 375

 Leu Gln Leu Ala Leu Pro Asp Trp Leu Asp Pro Ala Arg Thr Arg
                 380                 385                 390

 Leu Asn Gly Ala Lys Met Lys Gln Leu Phe Ser Ile Leu Glu Glu
                 395                 400                 405

 Leu Ala Met Val Thr Ser Leu Arg Pro Pro Val Gln Ala Asn Pro
                 410                 415                 420

 Asp Leu Leu Ser Leu Leu Thr Val Ser Leu Asp Gln Tyr Gln Thr
                 425                 430                 435

 Glu Asp Glu Leu Tyr Gln Leu Ser Leu Gln Arg Glu Pro Arg Ser
                 440                 445                 450

 Lys Ser Ser Pro Thr Ser Pro Thr Ser Cys Thr Pro Pro Pro Arg
                 455                 460                 465

 Pro Pro Val Leu Glu Glu Trp Thr Ser Ala Ala Lys Pro Lys Leu
                 470                 475                 480

 Asp Gln Ala Leu Val Val Glu His Ile Glu Lys Met Val Glu Ser
                 485                 490                 495

 Val Phe Arg Asn Phe Asp Val Asp Gly Asp Gly His Ile Ser Gln
                 500                 505                 510

 Glu Glu Phe Gln Ile Ile Arg Gly Asn Phe Pro Tyr Leu Ser Ala
                 515                 520                 525

 Phe Gly Asp Leu Asp Gln Asn Gln Asp Gly Cys Ile Ser Arg Glu
                 530                 535                 540

 Glu Met Val Ser Tyr Phe Leu Arg Ser Ser Ser Val Leu Gly Gly
                 545                 550                 555

 Arg Met Gly Phe Val His Asn Phe Gln Glu Ser Asn Ser Leu Arg
                 560                 565                 570

 Pro Val Ala Cys Arg His Cys Lys Ala Leu Ile Leu Gly Ile Tyr
                 575                 580                 585

 Lys Gln Gly Leu Lys Cys Arg Ala Cys Gly Val Asn Cys His Lys
                 590                 595                 600

 Gln Cys Lys Asp Arg Leu Ser Val Glu Cys Arg Arg Arg Ala Gln
                 605                 610                 615

 Ser Val Ser Leu Glu Gly Ser Ala Pro Ser Pro Ser Pro Met His
                 620                 625                 630

 Ser His His His Arg Ala Phe Ser Phe Ser Leu Pro Arg Pro Gly
                 635                 640                 645

 Arg Arg Gly Ser Arg Pro Pro Glu Ile Arg Glu Glu Glu Val Gln
                 650                 655                 660

 Thr Val Glu Asp Gly Val Phe Asp Ile His Leu
                 665                 670

<210> 1737
<211> 1579
<212> DNA
<213> Homo sapien

<400> 1737
 aattcggcac gagggcatgg ggcggctggt tctgctgtgg ggagctgccg 50

 tctttctgct gggaggctgg atggctttgg ggcaaggagg agcagcagaa 100

 ggagtacaga ttcagatcat ctacttcaat ttagaaaccg tgcaggtgac 150

 atggaatgcc agcaaatact ccaggaccaa cctgactttc cactacagat 200

 tcaacggtga tgaggcctat gaccagtgca ccaactacct tctccaggaa 250

 ggtcacactt cggggtgcct cctagacgca gagcagcgag acgacattct 300

 ctatttctcc atcaggaatg ggacgcaccc cgttttcacc gcaagtcgct 350

 ggatggttta ttacctgaaa cccagttccc cgaagcacgt gagattttcg 400

 tggcatcagg atgcagtgac ggtgacgtgt tctgacctgt cctacgggga 450

 tctcctctat gaggttcagt accggagccc cttcgacacc gagtggcagt 500

 ccaaacagga aaatacctgc aacgtcacca tagaaggctt ggatgccgag 550

 aagtgttact ctttctgggt cagggtgaag gctatggagg atgtatatgg 600

 gccagacaca tacccaagcg actggtcaga ggtgacatgc tggcagagag 650

 gcgagattcg ggatgcctgt gcagagacac caacgcctcc caaaccaaag 700

 ctgtccaaat ttattttaat ttccagcctg gccatccttc tgatggtgtc 750

 tctcctcctt ctgtctttat ggaaattatg gagagtgaag aagtttctca 800

 ttcccagcgt gccagacccg aaatccatct tccccgggct ctttgagata 850

 caccaaggga acttccagga gtggatcaca gacacccaga acgtggccca 900

 cctccacaag atggcaggtg cagagcaaga aagtggcccc gaggagcccc 950

 tggtagtcca gttggccaag actgaagccg agtctcccag gatgctggac 1000

 ccacagaccg aggagaaaga ggcctctggg ggatccctcc agcttcccca 1050

 ccagcccctc caaggcggtg atgtggtcac aatcgggggc ttcacctttg 1100

 tgatgaatga ccgctcctac gtggcgttgt gatggacaca ccactgtcaa 1150

 agtcaacgtc aggatccacg ttgacattta aagacagagg ggactgtccc 1200

 ggggactcca caccaccatg gatgggaagt ctccacgcca atgatggtag 1250

 gactaggaga ctctgaagac ccagcctcac cgcctaatgc ggccactgcc 1300

 ctgctaactt tcccccacat gagtctctgt gttcaaaggc ttgatggcag 1350

 atgggagcca attgctccag gagatttact cccagttcct tttcgtgcct 1400

 gaacgttgtc acataaaccc caaggcagca cgtccaaaat gctgtaaaac 1450

 catcttccca ctctgtgagt ccccagttcc gtccatgtac ctgttccata 1500

 gcattggatt ctcggaggat tttttgtctg ttttgagact ccaaaccacc 1550

 tctaccccta caaaaaaaaa aaaaaaaaa 1579

<210> 1738
<211> 371
<212> PRT
<213> Homo sapien

<400> 1738
 Met Gly Arg Leu Val Leu Leu Trp Gly Ala Ala Val Phe Leu Leu
   1               5                  10                  15

 Gly Gly Trp Met Ala Leu Gly Gln Gly Gly Ala Ala Glu Gly Val
                  20                  25                  30

 Gln Ile Gln Ile Ile Tyr Phe Asn Leu Glu Thr Val Gln Val Thr
                  35                  40                  45

 Trp Asn Ala Ser Lys Tyr Ser Arg Thr Asn Leu Thr Phe His Tyr
                  50                  55                  60

 Arg Phe Asn Gly Asp Glu Ala Tyr Asp Gln Cys Thr Asn Tyr Leu
                  65                  70                  75

 Leu Gln Glu Gly His Thr Ser Gly Cys Leu Leu Asp Ala Glu Gln
                  80                  85                  90

 Arg Asp Asp Ile Leu Tyr Phe Ser Ile Arg Asn Gly Thr His Pro
                  95                 100                 105

 Val Phe Thr Ala Ser Arg Trp Met Val Tyr Tyr Leu Lys Pro Ser
                 110                 115                 120

 Ser Pro Lys His Val Arg Phe Ser Trp His Gln Asp Ala Val Thr
                 125                 130                 135

 Val Thr Cys Ser Asp Leu Ser Tyr Gly Asp Leu Leu Tyr Glu Val
                 140                 145                 150

 Gln Tyr Arg Ser Pro Phe Asp Thr Glu Trp Gln Ser Lys Gln Glu
                 155                 160                 165

 Asn Thr Cys Asn Val Thr Ile Glu Gly Leu Asp Ala Glu Lys Cys
                 170                 175                 180

 Tyr Ser Phe Trp Val Arg Val Lys Ala Met Glu Asp Val Tyr Gly
                 185                 190                 195

 Pro Asp Thr Tyr Pro Ser Asp Trp Ser Glu Val Thr Cys Trp Gln
                 200                 205                 210

 Arg Gly Glu Ile Arg Asp Ala Cys Ala Glu Thr Pro Thr Pro Pro
                 215                 220                 225

 Lys Pro Lys Leu Ser Lys Phe Ile Leu Ile Ser Ser Leu Ala Ile
                 230                 235                 240

 Leu Leu Met Val Ser Leu Leu Leu Leu Ser Leu Trp Lys Leu Trp
                 245                 250                 255

 Arg Val Lys Lys Phe Leu Ile Pro Ser Val Pro Asp Pro Lys Ser
                 260                 265                 270

 Ile Phe Pro Gly Leu Phe Glu Ile His Gln Gly Asn Phe Gln Glu
                 275                 280                 285

 Trp Ile Thr Asp Thr Gln Asn Val Ala His Leu His Lys Met Ala
                 290                 295                 300

 Gly Ala Glu Gln Glu Ser Gly Pro Glu Glu Pro Leu Val Val Gln
                 305                 310                 315

 Leu Ala Lys Thr Glu Ala Glu Ser Pro Arg Met Leu Asp Pro Gln
                 320                 325                 330

 Thr Glu Glu Lys Glu Ala Ser Gly Gly Ser Leu Gln Leu Pro His
                 335                 340                 345

 Gln Pro Leu Gln Gly Gly Asp Val Val Thr Ile Gly Gly Phe Thr
                 350                 355                 360

 Phe Val Met Asn Asp Arg Ser Tyr Val Ala Leu
                 365                 370

<210> 1739
<211> 1201
<212> DNA
<213> Homo sapien

<400> 1739
 tttttcttct tctatcacag ggagaagtga aatgacaacc tcactagata 50

 cagttgagac ctttggtacc acatcctact atgatgacgt gggcctgctc 100

 tgtgaaaaag ctgataccag agcactgatg gcccagtttg tgcccccgct 150

 gtactccctg gtgttcactg tgggcctctt gggcaatgtg gtggtggtga 200

 tgatcctcat aaaatacagg aggctccgaa ttatgaccaa catctacctg 250

 ctcaacctgg ccatttcgga cctgctcttc ctcgtcaccc ttccattctg 300

 gatccactat gtcagggggc ataactgggt ttttggccat ggcatgtgta 350

 agctcctctc agggttttat cacacaggct tgtacagcga gatctttttc 400

 ataatcctgc tgacaatcga caggtacctg gccattgtcc atgctgtgtt 450

 tgcccttcga gcccggactg tcacttttgg tgtcatcacc agcatcgtca 500

 cctggggcct ggcagtgcta gcagctcttc ctgaatttat cttctatgag 550

 actgaagagt tgtttgaaga gactctttgc agtgctcttt acccagagga 600

 tacagtatat agctggaggc atttccacac tctgagaatg accatcttct 650

 gtctcgttct ccctctgctc gttatggcca tctgctacac aggaatcatc 700

 aaaacgctgc tgaggtgccc cagtaaaaaa aagtacaagg ccatccggct 750

 catttttgtc atcatggcgg tgtttttcat tttctggaca ccctacaatg 800

 tggctatcct tctctcttcc tatcaatcca tcttatttgg aaatgactgt 850

 gagcggagca agcatctgga cctggtcatg ctggtgacag aggtgatcgc 900

 ctactcccac tgctgcatga acccggtgat ctacgccttt gttggagaga 950

 ggttccggaa gtacctgcgc cacttcttcc acaggcactt gctcatgcac 1000

 ctgggcagat acatcccatt ccttcctagt gagaagctgg aaagaaccag 1050

 ctctgtctct ccatccacag cagagccgga actctctatt gtgttttagg 1100

 tcagatgcag aaaattgcct aaagaggaag gaccaaggag atgaagcaaa 1150

 cacattaagc cttccacact cacctctaaa acagtccttc aaacttccag 1200

 t 1201

<210> 1740
<211> 355
<212> PRT
<213> Homo sapien

<400> 1740
 Met Thr Thr Ser Leu Asp Thr Val Glu Thr Phe Gly Thr Thr Ser
   1               5                  10                  15

 Tyr Tyr Asp Asp Val Gly Leu Leu Cys Glu Lys Ala Asp Thr Arg
                  20                  25                  30

 Ala Leu Met Ala Gln Phe Val Pro Pro Leu Tyr Ser Leu Val Phe
                  35                  40                  45

 Thr Val Gly Leu Leu Gly Asn Val Val Val Val Met Ile Leu Ile
                  50                  55                  60

 Lys Tyr Arg Arg Leu Arg Ile Met Thr Asn Ile Tyr Leu Leu Asn
                  65                  70                  75

 Leu Ala Ile Ser Asp Leu Leu Phe Leu Val Thr Leu Pro Phe Trp
                  80                  85                  90

 Ile His Tyr Val Arg Gly His Asn Trp Val Phe Gly His Gly Met
                  95                 100                 105

 Cys Lys Leu Leu Ser Gly Phe Tyr His Thr Gly Leu Tyr Ser Glu
                 110                 115                 120

 Ile Phe Phe Ile Ile Leu Leu Thr Ile Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val His Ala Val Phe Ala Leu Arg Ala Arg Thr Val Thr Phe Gly
                 140                 145                 150

 Val Ile Thr Ser Ile Val Thr Trp Gly Leu Ala Val Leu Ala Ala
                 155                 160                 165

 Leu Pro Glu Phe Ile Phe Tyr Glu Thr Glu Glu Leu Phe Glu Glu
                 170                 175                 180

 Thr Leu Cys Ser Ala Leu Tyr Pro Glu Asp Thr Val Tyr Ser Trp
                 185                 190                 195

 Arg His Phe His Thr Leu Arg Met Thr Ile Phe Cys Leu Val Leu
                 200                 205                 210

 Pro Leu Leu Val Met Ala Ile Cys Tyr Thr Gly Ile Ile Lys Thr
                 215                 220                 225

 Leu Leu Arg Cys Pro Ser Lys Lys Lys Tyr Lys Ala Ile Arg Leu
                 230                 235                 240

 Ile Phe Val Ile Met Ala Val Phe Phe Ile Phe Trp Thr Pro Tyr
                 245                 250                 255

 Asn Val Ala Ile Leu Leu Ser Ser Tyr Gln Ser Ile Leu Phe Gly
                 260                 265                 270

 Asn Asp Cys Glu Arg Ser Lys His Leu Asp Leu Val Met Leu Val
                 275                 280                 285

 Thr Glu Val Ile Ala Tyr Ser His Cys Cys Met Asn Pro Val Ile
                 290                 295                 300

 Tyr Ala Phe Val Gly Glu Arg Phe Arg Lys Tyr Leu Arg His Phe
                 305                 310                 315

 Phe His Arg His Leu Leu Met His Leu Gly Arg Tyr Ile Pro Phe
                 320                 325                 330

 Leu Pro Ser Glu Lys Leu Glu Arg Thr Ser Ser Val Ser Pro Ser
                 335                 340                 345

 Thr Ala Glu Pro Glu Leu Ser Ile Val Phe
                 350                 355

<210> 1741
<211> 1165
<212> DNA
<213> Homo sapien

<400> 1741
 tctccctgag tgagactcac ctgctcctct ccggggtggt cctgtcctgt 50

 tctccagcat ggtgtgtctg aagttccctg gaggctcctg catggcagct 100

 ctgacagtga cactgatggt gctgagctcc ccactggctt tggctgggga 150

 cacccgacca cgtttcttgg agcaggttaa acatgagtgt catttcttca 200

 acgggacgga gcgggtgcgg ttcctggaca gatacttcta tcaccaagag 250

 gagtacgtgc gcttcgacag cgacgtgggg gagtaccggg cggtgacgga 300

 gctggggcgg cctgatgccg agtactggaa cagccagaag gacctcctgg 350

 agcagaggcg ggccgcggtg gacacctact gcagacacaa ctacggggtt 400

 gtggagagct tcacagtgca gcggcgagtc tatcctgagg tgactgtgta 450

 tcctgcaaag acccagcccc tgcagcacca caacctcctg gtctgctctg 500

 tgaatggttt ctatccaggc agcattgaag tcaggtggtt ccggaacggc 550

 caggaagaga agactggggt ggtgtccaca ggcctgatcc agaatggaga 600

 ctggaccttc cagaccctgg tgatgctgga aacagttcct cggagtggag 650

 aggtttacac ctgccaagtg gagcacccaa gcctgacgag ccctctcaca 700

 gtggaatgga gagcacggtc tgaatctgca cagagcaaga tgctgagtgg 750

 agtcgggggc ttcgtgctgg gcctgctctt ccttggggcc gggctgttca 800

 tctacttcag gaatcagaaa ggacactctg gacttcagcc aacaggtaat 850

 accttttcat cctctttaag aaacagattt ggaggccagg cgcagtggct 900

 cacgcctgta atcccagcac tttgggaggc cgaggcgggc gaatcatgag 950

 gtcaggagtt cgagaccagc ctgaccaacg tggtgaaacc ccgtctctac 1000

 taaaaataca aaaaaaaatc agtcgggcgt ggtggtgtgc gctgtaatcc 1050

 agctactcag gaggccaagg caggagaatc gctggaaccc gggaggcaga 1100

 ggttgcagtg agccgagatt gggccactgc actccagcct aggtgacaga 1150

 gtgagacccc atctc 1165

<210> 1742
<211> 296
<212> PRT
<213> Homo sapien

<400> 1742
 Met Val Cys Leu Lys Phe Pro Gly Gly Ser Cys Met Ala Ala Leu
   1               5                  10                  15

 Thr Val Thr Leu Met Val Leu Ser Ser Pro Leu Ala Leu Ala Gly
                  20                  25                  30

 Asp Thr Arg Pro Arg Phe Leu Glu Gln Val Lys His Glu Cys His
                  35                  40                  45

 Phe Phe Asn Gly Thr Glu Arg Val Arg Phe Leu Asp Arg Tyr Phe
                  50                  55                  60

 Tyr His Gln Glu Glu Tyr Val Arg Phe Asp Ser Asp Val Gly Glu
                  65                  70                  75

 Tyr Arg Ala Val Thr Glu Leu Gly Arg Pro Asp Ala Glu Tyr Trp
                  80                  85                  90

 Asn Ser Gln Lys Asp Leu Leu Glu Gln Arg Arg Ala Ala Val Asp
                  95                 100                 105

 Thr Tyr Cys Arg His Asn Tyr Gly Val Val Glu Ser Phe Thr Val
                 110                 115                 120

 Gln Arg Arg Val Tyr Pro Glu Val Thr Val Tyr Pro Ala Lys Thr
                 125                 130                 135

 Gln Pro Leu Gln His His Asn Leu Leu Val Cys Ser Val Asn Gly
                 140                 145                 150

 Phe Tyr Pro Gly Ser Ile Glu Val Arg Trp Phe Arg Asn Gly Gln
                 155                 160                 165

 Glu Glu Lys Thr Gly Val Val Ser Thr Gly Leu Ile Gln Asn Gly
                 170                 175                 180

 Asp Trp Thr Phe Gln Thr Leu Val Met Leu Glu Thr Val Pro Arg
                 185                 190                 195

 Ser Gly Glu Val Tyr Thr Cys Gln Val Glu His Pro Ser Leu Thr
                 200                 205                 210

 Ser Pro Leu Thr Val Glu Trp Arg Ala Arg Ser Glu Ser Ala Gln
                 215                 220                 225

 Ser Lys Met Leu Ser Gly Val Gly Gly Phe Val Leu Gly Leu Leu
                 230                 235                 240

 Phe Leu Gly Ala Gly Leu Phe Ile Tyr Phe Arg Asn Gln Lys Gly
                 245                 250                 255

 His Ser Gly Leu Gln Pro Thr Gly Asn Thr Phe Ser Ser Ser Leu
                 260                 265                 270

 Arg Asn Arg Phe Gly Gly Gln Ala Gln Trp Leu Thr Pro Val Ile
                 275                 280                 285

 Pro Ala Leu Trp Glu Ala Glu Ala Gly Glu Ser
                 290                 295

<210> 1743
<211> 5029
<212> DNA
<213> Homo sapien

<400> 1743
 cgaggctccg tgccccgccc cccgggtgcc ccgccccttt gcgcggctgg 50

 cgcggccagc cggccaggct cccctcggca aacctgtcta attggggcgg 100

 ggagcggagc ttcctcctct gagggccgtg ccgcgctgcc agatttgttc 150

 ttccgcccct gcctccgcgg ctcggaggcg agcggaaggt gccccggggc 200

 cgaggcccgt gacggggcgg gcgggagccc cggcagtccg gggtcgccgg 250

 cgagggccat gtcgctgttg ggggacccgc tacaggccct gccgccctcg 300

 gccgccccca cggggccgct gctcgcccct ccggccggcg cgaccctcaa 350

 ccgcctgcgg gagccgctgc tgcggaggct cagcgagctc ctggatcagg 400

 cgcccgaggg ccggggctgg aggagactgg cggagctggc ggggagtcgc 450

 gggcgcctcc gcctcagttg cctagacctg gagcagtgtt ctcttaaggt 500

 actggagcct gaaggaagcc ccagcctgtg tctgctgaag ttaatgggtg 550

 aaaaaggttg cacagtcaca gaattgagtg atttcctgca ggctatggaa 600

 cacactgaag ttcttcagct tctcagcccc ccaggaataa agattactgt 650

 aaacccagag tcaaaggcag tcttggctgg acagtttgtg aaactgtgtt 700

 gccgggcaac tggacatcct tttgttcaat atcagtggtt caaaatgaat 750

 aaagagattc caaatggaaa tacatcagag cttattttta atgcagtgca 800

 tgtaaaagat gcaggctttt atgtctgtcg agttaataac aatttcacct 850

 ttgaattcag ccagtggtca cagctggatg tttgcgacat cccagagagc 900

 ttccagagaa gtgttgatgg cgtctctgaa tccaagttgc aaatctgtgt 950

 tgaaccaact tcccaaaagc tgatgccagg cagcacattg gttttacagt 1000

 gtgttgctgt tggaagccct attcctcact accagtggtt caaaaatgaa 1050

 ttaccattaa cacatgagac caaaaagcta tacatggtgc cttatgtgga 1100

 tttggaacac caaggaacct actggtgtca tgtatataat gatcgagaca 1150

 gtcaagatag caagaaggta gaaatcatca taggaagaac agatgaggca 1200

 gtggagtgca ctgaagatga attaaataat cttggtcatc ctgataataa 1250

 agagcaaaca actgaccagc ctttggcgaa ggacaaggtt gcccttttga 1300

 taggaaatat gaattaccgg gagcacccca agctcaaagc tcctttggtg 1350

 gatgtgtacg aattgactaa cttactgaga cagctggact tcaaagtggt 1400

 ttcactgttg gatcttactg aatatgagat gcgtaatgct gtggatgagt 1450

 ttttactcct tttagacaag ggagtatatg ggttattata ttatgcagga 1500

 catggttatg aaaattttgg gaacagcttc atggtccccg ttgatgctcc 1550

 aaatccatat aggtctgaaa attgtctgtg tgtacaaaat atactgaaat 1600

 tgatgcaaga aaaagaaact ggacttaatg tgttcttatt ggatatgtgt 1650

 aggaaaagaa atgactacga tgataccatt ccaatcttgg atgcactaaa 1700

 agtcaccgcc aatattgtgt ttggatatgc cacgtgtcaa ggagcagaag 1750

 cttttgaaat ccagcattct ggattggcaa atggaatctt tatgaaattt 1800

 ttaaaagaca gattattaga agataagaaa atcactgtgt tactggatga 1850

 agttgcagaa gatatgggta agtgtcacct taccaaaggc aaacaggctc 1900

 tagagattcg aagtagttta tctgagaaga gagcacttac tgatccaata 1950

 cagggaacag aatattctgc tgaatctctt gtgcggaatc tacagtgggc 2000

 caaggctcat gaacttccag aaagtatgtg tcttaagttt gactgtggtg 2050

 ttcagattca attaggattt gcagctgagt tttccaatgt catgatcatc 2100

 tatacaagta tagtttacaa accaccggag ataataatgt gtgatgccta 2150

 cgttactgat tttccacttg atctagatat tgatccaaaa gatgcaaata 2200

 aaggcacacc tgaagaaact ggcagctact tggtatcaaa ggatcttccc 2250

 aagcattgcc tctataccag actcagttca ctgcaaaaat taaaggaaca 2300

 tctagtcttc acagtatgtt tatcatatca gtactcagga ttggaagata 2350

 ctgtagagga caagcaggaa gtgaatgttg ggaaacctct cattgctaaa 2400

 ttagacatgc atcgaggttt gggaaggaag acttgctttc aaacttgtct 2450

 tatgtctaat ggtccttacc agagttctgc agccacctca ggaggagcag 2500

 ggcattatca ctcattgcaa gacccattcc atggtgttta ccattcacat 2550

 cctggtaatc caagtaatgt tacaccagca gatagctgtc attgcagccg 2600

 gactccagat gcatttattt caagtttcgc tcaccatgct tcatgtcatt 2650

 ttagtagaag taatgtgcca gtagagacaa ctgatgaaat accatttagt 2700

 ttctctgaca ggctcagaat ttctgaaaaa tgacctcctt gtttttgaaa 2750

 gttagcataa ttttagatgc ctgtgaaata gtactgcact tacataaagt 2800

 gagacattgt gaaaaggcaa atttgtatat gtagagaaag aatagtagta 2850

 actgtttcat agcaaacttc aggactttga gatgttgaaa ttacattatt 2900

 taattacaga cttcctcttt ctaagatttt gtgaattggt tgaatagttc 2950

 tatacaaatg aagtatggag gtgtgtatgt ttatatgtat ataacaaaat 3000

 attttcattg tgaccactct gaagtaagag caatgggaat ggcattattg 3050

 tagaataagt cattgtattt ttaacaccag aaagaacctt gccgatcacc 3100

 aggcataacc taattttatc catggaagaa acacagaaag gcatctaagt 3150

 tagagctggc accagaactg agacctccag aaatctattc cagtattttt 3200

 tccactacac aactgccttc ctgacaggtt ctgagataag tgttatgttt 3250

 gtagatagag tgaaatatat ttatatatat ataaatatat acagatacat 3300

 atctgtgtat tatctcaagg aatgtacaaa ctttagtttt tgattataag 3350

 gacttcactg caagttttag ttaagaggtt tgtatataaa tctgttatag 3400

 aacaggctga aatttcttgt tcataagatt atgaaaccac atgagaagtg 3450

 ataaaatgtt tgttaaagct agatagaggt taagaatcaa gatataatgg 3500

 ataattttca tagctgccta tcagaatttc ccaaatattt agcatcttcc 3550

 ttgataatat gtattttctt cttgaatttc actggcctaa tgagataata 3600

 ctcttatctt tggctctacc taaaagttgg ttaaaaatgc aattggcatt 3650

 aacaaggaaa aatactgaat tagtaatttt aaaagtctca caaagaaaat 3700

 cccaggccta gatggctgca ttgttgaatt ctgccaaaca ttaaaattag 3750

 cactaatttt ttgcacactg tttctaaaag taggagagga aagaacactt 3800

 cccaacttac tctaggtcag tattaccctg atactagact agacatcaca 3850

 agaaaactat aagccaatat tccttattaa tacaaacaca aaaatcatta 3900

 acaaaaatat tagcaaactg aatccagcaa cctataaaaa ggattctata 3950

 tcatgaccaa gtggaattta tcccaggaat tcaaggttgg ttcaacatct 4000

 aaaaatcaaa taagctaata tacagtcagt tctcattatt cacagtaatt 4050

 atgttctaca gaatattctc ccataaacac tgaattaaat atggaacaac 4100

 tgcttttagg agaaagtgta tttgtgtata tgtgtgtata catatgttta 4150

 tctcacacac attatgagct tgaattctta attcatccta gcaaattcta 4200

 ccttatttta cagaagtgaa agtgaggtat cagaagtgtt aagtgacatg 4250

 cctgaggcac ccccctaaca ggtgtcagag ctgaaattca aaccccatcc 4300

 agctggcccc ggagccagag cttcttgtac tacacagaat tgcccctgcc 4350

 atttccaccc tccagtcatt tctctatgag actgaagcag gaaggcagag 4400

 catcatcttg ttcagcctca gctgggaaca tgtgtactgg gtgactcaaa 4450

 tttttcaccc atttacacat atccacaaat gactgcaaaa gtgccacgga 4500

 tatcaatttg agggttataa attttagcaa gttggtaaat tcacaaatac 4550

 ataaccttga ataatgagga tcaactgtac catatttaat aaagcacaaa 4600

 acccacacag attgtcttat tacagcattt gataaaatcc aaaactcttt 4650

 cataaaaaca ctcaacaaac ttaggaataa aaggaatctt cctagatatg 4700

 ataaatataa catctatgaa aagcccacac ctaacattat acttcatggt 4750

 gatagactga aggctgaatg ttttcccctt aagattggga agaaggacaa 4800

 ggatgttcac tcggcactac ttctattcag cattgtactt gaagttctag 4850

 ccacagcagt taggttagga attcaaggtt tgttcaacat ctaaaaatca 4900

 aataagctaa taaagaaaag aggtttatac tgcaaaagaa gtgaaactat 4950

 atgtattcac agttgataca tagttgtata tagaaaatgc taaagaatcc 5000

 ataaaaagta ataaatgagt tcaacaggt 5029

<210> 1744
<211> 824
<212> PRT
<213> Homo sapien

<400> 1744
 Met Ser Leu Leu Gly Asp Pro Leu Gln Ala Leu Pro Pro Ser Ala
   1               5                  10                  15

 Ala Pro Thr Gly Pro Leu Leu Ala Pro Pro Ala Gly Ala Thr Leu
                  20                  25                  30

 Asn Arg Leu Arg Glu Pro Leu Leu Arg Arg Leu Ser Glu Leu Leu
                  35                  40                  45

 Asp Gln Ala Pro Glu Gly Arg Gly Trp Arg Arg Leu Ala Glu Leu
                  50                  55                  60

 Ala Gly Ser Arg Gly Arg Leu Arg Leu Ser Cys Leu Asp Leu Glu
                  65                  70                  75

 Gln Cys Ser Leu Lys Val Leu Glu Pro Glu Gly Ser Pro Ser Leu
                  80                  85                  90

 Cys Leu Leu Lys Leu Met Gly Glu Lys Gly Cys Thr Val Thr Glu
                  95                 100                 105

 Leu Ser Asp Phe Leu Gln Ala Met Glu His Thr Glu Val Leu Gln
                 110                 115                 120

 Leu Leu Ser Pro Pro Gly Ile Lys Ile Thr Val Asn Pro Glu Ser
                 125                 130                 135

 Lys Ala Val Leu Ala Gly Gln Phe Val Lys Leu Cys Cys Arg Ala
                 140                 145                 150

 Thr Gly His Pro Phe Val Gln Tyr Gln Trp Phe Lys Met Asn Lys
                 155                 160                 165

 Glu Ile Pro Asn Gly Asn Thr Ser Glu Leu Ile Phe Asn Ala Val
                 170                 175                 180

 His Val Lys Asp Ala Gly Phe Tyr Val Cys Arg Val Asn Asn Asn
                 185                 190                 195

 Phe Thr Phe Glu Phe Ser Gln Trp Ser Gln Leu Asp Val Cys Asp
                 200                 205                 210

 Ile Pro Glu Ser Phe Gln Arg Ser Val Asp Gly Val Ser Glu Ser
                 215                 220                 225

 Lys Leu Gln Ile Cys Val Glu Pro Thr Ser Gln Lys Leu Met Pro
                 230                 235                 240

 Gly Ser Thr Leu Val Leu Gln Cys Val Ala Val Gly Ser Pro Ile
                 245                 250                 255

 Pro His Tyr Gln Trp Phe Lys Asn Glu Leu Pro Leu Thr His Glu
                 260                 265                 270

 Thr Lys Lys Leu Tyr Met Val Pro Tyr Val Asp Leu Glu His Gln
                 275                 280                 285

 Gly Thr Tyr Trp Cys His Val Tyr Asn Asp Arg Asp Ser Gln Asp
                 290                 295                 300

 Ser Lys Lys Val Glu Ile Ile Ile Gly Arg Thr Asp Glu Ala Val
                 305                 310                 315

 Glu Cys Thr Glu Asp Glu Leu Asn Asn Leu Gly His Pro Asp Asn
                 320                 325                 330

 Lys Glu Gln Thr Thr Asp Gln Pro Leu Ala Lys Asp Lys Val Ala
                 335                 340                 345

 Leu Leu Ile Gly Asn Met Asn Tyr Arg Glu His Pro Lys Leu Lys
                 350                 355                 360

 Ala Pro Leu Val Asp Val Tyr Glu Leu Thr Asn Leu Leu Arg Gln
                 365                 370                 375

 Leu Asp Phe Lys Val Val Ser Leu Leu Asp Leu Thr Glu Tyr Glu
                 380                 385                 390

 Met Arg Asn Ala Val Asp Glu Phe Leu Leu Leu Leu Asp Lys Gly
                 395                 400                 405

 Val Tyr Gly Leu Leu Tyr Tyr Ala Gly His Gly Tyr Glu Asn Phe
                 410                 415                 420

 Gly Asn Ser Phe Met Val Pro Val Asp Ala Pro Asn Pro Tyr Arg
                 425                 430                 435

 Ser Glu Asn Cys Leu Cys Val Gln Asn Ile Leu Lys Leu Met Gln
                 440                 445                 450

 Glu Lys Glu Thr Gly Leu Asn Val Phe Leu Leu Asp Met Cys Arg
                 455                 460                 465

 Lys Arg Asn Asp Tyr Asp Asp Thr Ile Pro Ile Leu Asp Ala Leu
                 470                 475                 480

 Lys Val Thr Ala Asn Ile Val Phe Gly Tyr Ala Thr Cys Gln Gly
                 485                 490                 495

 Ala Glu Ala Phe Glu Ile Gln His Ser Gly Leu Ala Asn Gly Ile
                 500                 505                 510

 Phe Met Lys Phe Leu Lys Asp Arg Leu Leu Glu Asp Lys Lys Ile
                 515                 520                 525

 Thr Val Leu Leu Asp Glu Val Ala Glu Asp Met Gly Lys Cys His
                 530                 535                 540

 Leu Thr Lys Gly Lys Gln Ala Leu Glu Ile Arg Ser Ser Leu Ser
                 545                 550                 555

 Glu Lys Arg Ala Leu Thr Asp Pro Ile Gln Gly Thr Glu Tyr Ser
                 560                 565                 570

 Ala Glu Ser Leu Val Arg Asn Leu Gln Trp Ala Lys Ala His Glu
                 575                 580                 585

 Leu Pro Glu Ser Met Cys Leu Lys Phe Asp Cys Gly Val Gln Ile
                 590                 595                 600

 Gln Leu Gly Phe Ala Ala Glu Phe Ser Asn Val Met Ile Ile Tyr
                 605                 610                 615

 Thr Ser Ile Val Tyr Lys Pro Pro Glu Ile Ile Met Cys Asp Ala
                 620                 625                 630

 Tyr Val Thr Asp Phe Pro Leu Asp Leu Asp Ile Asp Pro Lys Asp
                 635                 640                 645

 Ala Asn Lys Gly Thr Pro Glu Glu Thr Gly Ser Tyr Leu Val Ser
                 650                 655                 660

 Lys Asp Leu Pro Lys His Cys Leu Tyr Thr Arg Leu Ser Ser Leu
                 665                 670                 675

 Gln Lys Leu Lys Glu His Leu Val Phe Thr Val Cys Leu Ser Tyr
                 680                 685                 690

 Gln Tyr Ser Gly Leu Glu Asp Thr Val Glu Asp Lys Gln Glu Val
                 695                 700                 705

 Asn Val Gly Lys Pro Leu Ile Ala Lys Leu Asp Met His Arg Gly
                 710                 715                 720

 Leu Gly Arg Lys Thr Cys Phe Gln Thr Cys Leu Met Ser Asn Gly
                 725                 730                 735

 Pro Tyr Gln Ser Ser Ala Ala Thr Ser Gly Gly Ala Gly His Tyr
                 740                 745                 750

 His Ser Leu Gln Asp Pro Phe His Gly Val Tyr His Ser His Pro
                 755                 760                 765

 Gly Asn Pro Ser Asn Val Thr Pro Ala Asp Ser Cys His Cys Ser
                 770                 775                 780

 Arg Thr Pro Asp Ala Phe Ile Ser Ser Phe Ala His His Ala Ser
                 785                 790                 795

 Cys His Phe Ser Arg Ser Asn Val Pro Val Glu Thr Thr Asp Glu
                 800                 805                 810

 Ile Pro Phe Ser Phe Ser Asp Arg Leu Arg Ile Ser Glu Lys
                 815                 820

<210> 1745
<211> 9618
<212> DNA
<213> Homo sapien

<400> 1745
 gcggccgctc ccccggagcg gctaaagcgg cggcgaccga ggcgagcaat 50

 gggcacggca gtctcggcag agcacaggcg cttcaccgcg gctgctcggg 100

 ctccgcgctg acctgcccgg gcggccgcct attgtctttc tccgcggcga 150

 aggtgaagag ttgtcccagc tcggcccgcg ggggagcccc gggagccgca 200

 cgtgtcctgg gtcatgaaac ttaatccaca gcaagctccc ttatatggtg 250

 attgtgttgt tacagtgctg cttgctgaag aggacaaagc tgaagatgat 300

 gtagtgtttt acttggtatt tttgggttcc accctccgtc actgtacaag 350

 tactcggaag gtcagttctg atacattgga gaccattgct cctggtcatg 400

 attgttgtga aacagtgaag gtgcagctct gtgcttccaa agagggcctt 450

 cccgtgtttg tggtggctga agaagacttt catttcgtcc aggatgaagc 500

 gtatgatgca gctcaattcc tagcaaccag tgctggaaat cagcaggctt 550

 tgaactttac ccgttttctt gaccagtcag gacccccatc tggggatgtg 600

 aattcccttg ataagaagtt ggtgctggca ttcaggcacc tgaagctgcc 650

 cacggagtgg aatgtattgg ggacagatca gagtttgcat gatgctggcc 700

 cgcgagagac attgatgcat tttgctgtgc ggctgggact gctgaggttg 750

 acgtggttcc tgttgcagaa gccaggtggc cgcggagctc tcagtatcca 800

 caaccaggaa ggggcgacgc ctgtgagctt ggccttggag cgaggctatc 850

 acaagctgca ccagcttcta accgaggaga atgctggaga accagactcc 900

 tggagcagtt tatcctatga aataccgtat ggagactgtt ctgtgaggca 950

 tcatcgagag ttggacatct atacattaac ctctgagtct gattcacatc 1000

 atgaacaccc atttcctgga gacggttgca ctggaccaat ttttaaactt 1050

 atgaacatcc aacagcaact aatgaaaaca aacctcaagc agatggacag 1100

 tcttatgccc ttaatgatga cagcacagga tccttccagt gccccagaga 1150

 cagatggcca gtttcttccc tgtgcaccgg agcccacgga ccctcagcga 1200

 ctttcttctt ctgaagagac tgagagcact cagtgctgcc cagggagccc 1250

 tgttgcacag actgaaagtc cctgtgattt gtcaagcata gttgaggagg 1300

 agaatacaga ccgttcctgt aggaagaaaa ataaaggcgt ggaaagaaaa 1350

 ggggaagagg tggagccagc acctattgtg gactctggaa ctgtatctga 1400

 tcaagacagc tgccttcaga gcttgcctga ttgtggagta aagggcacgg 1450

 aaggcctttc gtcctgtgga aacagaaatg aagaaactgg aacaaaatct 1500

 tctggaatgc ccacagacca ggagtccctg agcagtggag atgctgtgct 1550

 tcagagagac ttggtcatgg agccaggcac agcccagtat tcctctggag 1600

 gtgaactggg aggcatttca acaacaaatg tcagtacccc agacactgca 1650

 ggggaaatgg aacatgggct catgaaccca gatgccactg tttggaagaa 1700

 tgtgcttcag ggaggggaaa gtacaaagga aagatttgag aactctaata 1750

 ttggcacagc tggagcctct gacgtgcacg tcacaagtaa gcctgtggat 1800

 aaaatcagtg ttccaaactg tgcccctgct gccagttccc tggatggtaa 1850

 caaacctgct gagtcttcac ttgcatttag taatgaagaa acctccactg 1900

 aaaaaacagc agaaacggaa acttcacgaa gtcgtgagga gagtgctgat 1950

 gctccagtag atcagaattc tgtggtgatt ccagctgctg caaaagacaa 2000

 gatttcagat ggattagaac cttatactct cttagcagca ggcataggtg 2050

 aggcaatgtc accctcagat ttagcccttc ttgggctgga agaagatgta 2100

 atgccacacc agaactcaga aacaaattca tctcatgctc aaagccaaaa 2150

 gggcaaatcc tcacccattt gttctacaac tggagacgat aaactttgtg 2200

 cagactctgc atgtcaacag aacacagtga cttctagtgg cgatttggtt 2250

 gcaaaactgt gtgataacat agttagcgag tccgaaagca ccacagcaag 2300

 gcaacccagc tcacaagatc cacccgatgc ctcccactgt gaagacccac 2350

 aggctcatac agtcacctct gaccctgtaa gggataccca ggaacgtgcg 2400

 gatttttgtc ctttcaaagt ggtggataac aaaggccaac gaaaagatgt 2450

 gaaactagat aaacctttaa caaatatgct tgaggtggtt tcacatccac 2500

 atccagttgt ccctaaaatg gagaaagaac tggtgccaga ccaggcagta 2550

 atatcagaca gtactttctc tctggcaaac agtccaggca gtgaatcagt 2600

 aaccaaggat gacgcacttt cttttgtccc ctcccagaaa gaaaagggaa 2650

 cagcaactcc tgaactacat acagctacag attatagaga tggcccagat 2700

 ggaaattcga atgagcctga tacgcggcca ctagaagaca gggcagtagg 2750

 cctgtccaca tcctccactg ctgcagagct tcagcacggg atggggaata 2800

 ccagtctcac aggacttggt ggagagcatg aaggtcccgc ccctccagca 2850

 atcccagaag ctctgaatat caaggggaac actgactctt ccctgcaaag 2900

 tgtgggtaag gccactttgg ctttagattc agttttgact gaagaaggaa 2950

 aacttctggt ggtttcagaa agctctgcag ctcaggaaca agataaggat 3000

 aaagcggtga cctgttcctc tattaaggaa aatgctctct cttcaggaac 3050

 tttgcaggaa gagcagagaa caccacctcc tggacaagat actcaacaat 3100

 ttcatgaaaa atcaatctca gctgactgtg ccaaggacaa agcacttcag 3150

 ctaagtaatt caccgggtgc atcctctgcc tttcttaagg cagaaactga 3200

 acataacaag gaagtggccc cacaagtctc actgctgact caaggtgggg 3250

 ctgcccagag cctggtgcca ccaggagcaa gtctggccac agagtcaagg 3300

 caggaagcct tgggggcaga gcacaacagc tctgctctgt tgccatgtct 3350

 gttgccagat gggtctgatg ggtccgatgc tcttaactgc agtcagcctt 3400

 ctcctctgga tgttggagtg aagaacactc aatcccaggg aaaaactagt 3450

 gcctgtgagg tgagtggaga tgtgacggtg gatgttacag gggttaatgc 3500

 tctacaaggt atggctgagc ccagaagaga gaatatatca cacaacaccc 3550

 aagacatcct gattccaaac gtcttgttga gccaagagaa gaatgccgtt 3600

 ctaggtttgc cagtggctct acaggacaaa gctgtgactg acccacaggg 3650

 agttggaacc ccagagatga tacctcttga ttgggagaaa gggaagctgg 3700

 agggagcaga ccacagctgt accatgggtg acgctgagga agcccaaata 3750

 gacgatgaag cacatcctgt cctactgcag cctgttgcca aggagctccc 3800

 cacagacatg gagctctcag cccatgatga tggggcccca gctggtgtga 3850

 gggaagtcat gcgagccccg ccttcaggca gggaaaggag cactccctct 3900

 ctaccttgca tggtctctgc ccaggacgca cctctgccta agggggcaga 3950

 cttgatagag gaggctgcca gccgtatagt ggatgctgtc atcgaacaag 4000

 tcaaggccgc tggagcactg cttactgagg gggaggcctg tcacatgtca 4050

 ctgtccagcc ctgagttggg tcctctcact aaaggactag agagtgcttt 4100

 tacagaaaaa gtgagtactt tcccacctgg ggagagccta ccaatgggca 4150

 gtactcctga ggaagccacg gggagccttg caggatgttt tgctggaagg 4200

 gaggagccag agaagatcat tttacctgtc caggggcctg agccagcagc 4250

 agaaatgcca gacgtgaaag ctgaagatga agtggatttt agagcaagtt 4300

 caatttctga agaagtggct gtagggagca tagctgctac actgaagatg 4350

 aagcaaggcc caatgaccca ggcgataaac cgagaaaact ggtgtacaat 4400

 agagccatgc cctgatgcag catctcttct ggcttccaag cagagcccag 4450

 aatgtgagaa cttcctggat gttggactgg gcagagagtg tacctcaaaa 4500

 caaggtgtac ttaaaagaga atctgggagt gattctgacc tctttcactc 4550

 acccagtgat gacatggaca gcatcatctt cccaaagcca gaggaagagc 4600

 atttggcctg tgatatcacc ggatccagtt catccaccga tgacacggct 4650

 tcactggacc gacattcttc tcatggcagt gatgtgtctc tctcccagat 4700

 tttaaagcca aacaggtcaa gagatcggca aagccttgat ggattctaca 4750

 gccatgggat gggagctgag ggtcgagaaa gtgagagtga gcctgctgac 4800

 ccaggcgacg tggaggagga ggagatggac agtatcactg aagtgcctgc 4850

 aaactgctct gtcctaagga gctccatgcg ctctctttct cccttccgga 4900

 ggcacagctg ggggcctggg aaaaatgcag ccagcgatgc agaaatgaac 4950

 caccggagta tgagctggtg cccctctggt gtgcagtact ctgctggcct 5000

 gagtgctgac tttaattaca gaagtttcag tctagaaggc ttgacaggag 5050

 gagctggtgt cggaaacaag ccatcctcat ctctagaagt aagctctgca 5100

 aatgccgaag agctcagaca cccattcagt ggtgaggaac gggttgactc 5150

 tttggtgtca ctttcagaag aggatctgga gtcagaccag agagaacata 5200

 ggatgtttga tcagcagata tgtcacagat ctaagcagca gggatttaat 5250

 tactgtacat cagccatttc ctctccattg acaaaatcca tctcattaat 5300

 gacaatcagc catcctggat tggacaattc acggcccttc cacagtacct 5350

 tccacaatac cagtgctaat ctgactgaga gtataacaga agagaactat 5400

 aatttcctgc cacatagccc ctccaagaaa gattctgaat ggaagagtgg 5450

 aacaaaagtc agtcgtacat tcagctacat caagaataaa atgtctagca 5500

 gcaagaagag caaagaaaag gaaaaagaaa aagataagat taaggagaag 5550

 gagaaagatt ctaaagacaa ggagaaagat aagaagactg tcaacgggca 5600

 cactttcagt tccattcctg ttgtgggtcc catcagctgt agccagtgta 5650

 tgaagccctt caccaacaaa gatgcctata cttgtgcaaa ttgcagtgct 5700

 tttgtccaca aaggctgccg agaaagtcta gcctcctgtg caaaggtcaa 5750

 aatgaagcag cccaaaggga gccttcaggc acatgacaca tcatcactgc 5800

 ccacggtcat tatgagaaac aagccctcac agcccaagga gcgtcctcgg 5850

 tccgcagtcc tcctggtgga tgaaaccgct accaccccaa tatttgccaa 5900

 tagacgatcc cagcagagtg tctcgctctc caaaagtgtc tccatacaga 5950

 acattactgg agttggcaat gatgagaaca tgtcaaacac ctggaaattc 6000

 ctgtctcatt caacagactc actaaataaa atcagcaagg tcaatgagtc 6050

 aacagaatca cttactgatg agggagtagg tacagacatg aatgaaggac 6100

 aactactggg agactttgag attgagtcca aacagctgga agcagagtct 6150

 tggagtcgga taatagacag caagtttcta aaacagcaaa agaaagatgt 6200

 ggtcaaacgg caagaagtaa tatatgagtt gatgcagaca gagtttcatc 6250

 atgtccgcac tctcaagatc atgagtggtg tgtacagcca ggggatgatg 6300

 gcggatctgc tttttgagca gcagatggta gaaaagctgt tcccctgttt 6350

 ggatgagctg atcagtatcc atagccaatt cttccagagg attctggagc 6400

 ggaagaagga gtctctggtg gataaaagtg aaaagaactt tctcatcaag 6450

 aggatagggg atgtgcttgt aaatcagttt tcaggtgaga atgcagaacg 6500

 tttaaagaag acatatggca agttttgtgg gcaacataac cagtctgtaa 6550

 actacttcaa agacctttat gccaaggata agcgttttca agcctttgta 6600

 aagaagaaga tgagcagttc agttgttaga aggcttggaa ttccagagtg 6650

 catattgctt gtaactcagc ggattaccaa gtacccagtt ttattccaaa 6700

 gaatattgca gtgtaccaaa gacaatgaag tggagcagga agatctagca 6750

 cagtccttga gcctggtgaa ggatgtgatt ggagctgtag acagcaaagt 6800

 ggcaagttat gaaaagaaag tgcgtctcaa tgagatttat acaaagacag 6850

 atagcaagtc aatcatgagg atgaagagtg gtcagatgtt tgccaaggaa 6900

 gatttgaaac ggaagaagct tgtacgtgat gggagtgtgt ttctgaagaa 6950

 tgcagcagga aggttgaaag aggttcaagc agttcttctc actgacattt 7000

 tagttttcct tcaagaaaaa gaccagaagt acatctttgc atcattggac 7050

 cagaagtcaa cagtgatctc tttaaagaag ctgattgtga gagaagtggc 7100

 acatgaggag aaaggtttat tcctgatcag catggggatg acagatccag 7150

 agatggtaga agtccatgcc agctccaaag aggaacgaaa cagctggatt 7200

 cagatcattc aggacacaat caacaccctg aacagagatg aagatgaagg 7250

 aattcctagt gagaatgagg aagaaaagaa aatgttggac accagagccc 7300

 gagaattaaa agaacaactt caccagaagg accaaaaaat cctactcttg 7350

 ttggaagaga aggagatgat tttccgggac atggctgagt gcagcacccc 7400

 tctcccagag gattgctccc caacacatag ccctagagtt ctcttccgct 7450

 ccaacacaga agaggctctc aaaggaggac ctttaatgaa aagtgcaata 7500

 aatgaggtgg agatccttca gggtttggtg agtggaaatc tgggaggcac 7550

 acttgggccg actgtcagca gccccattga gcaagatgtg gtcagtcccg 7600

 tttccctgcc ccggagagca gagacctttg gaggatttga cagccatcag 7650

 atgaatgctt caaaaggagg cgagaaggaa gagggagatg atggccaaga 7700

 tcttaggaga acggaatcag atagtggcct aaaaaagggt ggaaatgcta 7750

 acctggtatt tatgcttaaa agaaacagtg agcaggttgt ccagagcgtt 7800

 gttcatctct acgagctcct cagcgctctg cagggtgtgg tgctgcagca 7850

 ggacagctac attgaggacc agaaactggt gctgagcgag agggcgctca 7900

 ctcgcagctt gtcccgcccg agctccctca ttgagcagga gaagcagcgc 7950

 agcctggaga agcagcgcca ggacctggcc aacctgcaga agcagcaggc 8000

 ccagtacctc gaggagaagc gcaggcgcga gcgtgagtgg gaagctcgtg 8050

 agagggagct gcgggagcgg gaggccctcc tggcccagcg cgaggaggag 8100

 gtgcagcagg ggcagcagga cctggaaaag gagcgggagg agctccagca 8150

 gaagaagggc acataccagt atgacctgga gcgactgcgt gctgcccaga 8200

 aacagcttga gagggaacag gagcagctgc gccgggaggc agagcggctc 8250

 agccagcggc agacagaacg ggacctgtgt caggtttccc atccacatac 8300

 caagctgatg aggatcccat cgttcttccc cagtcctgag gagcccccct 8350

 cgccatctgc accttccata gccaaatcag ggtcattgga ctcagaactt 8400

 tcagtgtccc caaaaaggaa cagcatctct cggacacaca aagataaggg 8450

 gccttttcac atactgagtt caaccagcca gacaaacaaa ggaccagaag 8500

 ggcagagcca ggcccctgcg tccacctctg cctctacccg cctgtttggg 8550

 ttaacaaagc caaaggaaaa gaaggagaaa aaaaagaaga acaaaaccag 8600

 ccgctctcag cccggtgatg gtcccgcgtc agaagtatca gcagagggtg 8650

 aagagatctt ctgctgaccc tcttcctctc tgctgaggca gctgcctcct 8700

 gatcctggcc agcccacctc tcctgctgtc cccgcgtgca caagtctctt 8750

 acactggacg cccactgctc ctcagcgtcc agtcctcctg ggcggcccca 8800

 ggtcctggac aataagcaac agatgatatt gagtgtcggg tggggaagga 8850

 ggcccagact ctgcttcggc catgatttgt gactgcccag gactctcagg 8900

 ttgggctggc cctactcagg attacactga aagtaatggc ctcgtaagta 8950

 caggtgatgg ttttggacac gtcaggaatt cctaaaggct gaaagagtgt 9000

 atccaagtaa ggtctgaacc tccgactgcc ttttatttgg gggaacacaa 9050

 aaccaaacag cagatgtttt ggacttgatc tgtgtacgta catggggacc 9100

 tgtctgcata tacacacggg gaatgccaga agaaggccca gtctgcacca 9150

 ggcgtctggt caacttagca caagggcagt gcctggacgg acccggagcc 9200

 cccgcatatc agcagttcac ccagtactcc tcagagactg gtttccctct 9250

 aaacccatcc cgggcacata ccacccctgt tttgcatgta tttctcattt 9300

 cattttaggg atgacaaaca tttgtgaaac cagtgagaga aggcttgatg 9350

 tgtataaaag acgtgatgtg caccacctcg atctcggtgt ttcaggcact 9400

 aaagcaacaa aacaacccat agtatctcat tttgtcatca gatccagaag 9450

 aaatatcctg gttttccagc atgtttaccc acatgttttg ggcatggata 9500

 aagtgaagag gcctactcac cattatccct gcagcgtgac accttttgat 9550

 tgtcactgac cactcagaag gggccacggc ctcctggctg tgttcctgag 9600

 aaaaaaaaaa aaaaaaaa 9618

<210> 1746
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1746
 Met Lys Leu Asn Pro Gln Gln Ala Pro Leu Tyr Gly Asp Cys Val
   1               5                  10                  15

 Val Thr Val Leu Leu Ala Glu Glu Asp Lys Ala Glu Asp Asp Val
                  20                  25                  30

 Val Phe Tyr Leu Val Phe Leu Gly Ser Thr Leu Arg His Cys Thr
                  35                  40                  45

 Ser Thr Arg Lys Val Ser Ser Asp Thr Leu Glu Thr Ile Ala Pro
                  50                  55                  60

 Gly His Asp Cys Cys Glu Thr Val Lys Val Gln Leu Cys Ala Ser
                  65                  70                  75

 Lys Glu Gly Leu Pro Val Phe Val Val Ala Glu Glu Asp Phe His
                  80                  85                  90

 Phe Val Gln Asp Glu Ala Tyr Asp Ala Ala Gln Phe Leu Ala Thr
                  95                 100                 105

 Ser Ala Gly Asn Gln Gln Ala Leu Asn Phe Thr Arg Phe Leu Asp
                 110                 115                 120

 Gln Ser Gly Pro Pro Ser Gly Asp Val Asn Ser Leu Asp Lys Lys
                 125                 130                 135

 Leu Val Leu Ala Phe Arg His Leu Lys Leu Pro Thr Glu Trp Asn
                 140                 145                 150

 Val Leu Gly Thr Asp Gln Ser Leu His Asp Ala Gly Pro Arg Glu
                 155                 160                 165

 Thr Leu Met His Phe Ala Val Arg Leu Gly Leu Leu Arg Leu Thr
                 170                 175                 180

 Trp Phe Leu Leu Gln Lys Pro Gly Gly Arg Gly Ala Leu Ser Ile
                 185                 190                 195

 His Asn Gln Glu Gly Ala Thr Pro Val Ser Leu Ala Leu Glu Arg
                 200                 205                 210

 Gly Tyr His Lys Leu His Gln Leu Leu Thr Glu Glu Asn Ala Gly
                 215                 220                 225

 Glu Pro Asp Ser Trp Ser Ser Leu Ser Tyr Glu Ile Pro Tyr Gly
                 230                 235                 240

 Asp Cys Ser Val Arg His His Arg Glu Leu Asp Ile Tyr Thr Leu
                 245                 250                 255

 Thr Ser Glu Ser Asp Ser His His Glu His Pro Phe Pro Gly Asp
                 260                 265                 270

 Gly Cys Thr Gly Pro Ile Phe Lys Leu Met Asn Ile Gln Gln Gln
                 275                 280                 285

 Leu Met Lys Thr Asn Leu Lys Gln Met Asp Ser Leu Met Pro Leu
                 290                 295                 300

 Met Met Thr Ala Gln Asp Pro Ser Ser Ala Pro Glu Thr Asp Gly
                 305                 310                 315

 Gln Phe Leu Pro Cys Ala Pro Glu Pro Thr Asp Pro Gln Arg Leu
                 320                 325                 330

 Ser Ser Ser Glu Glu Thr Glu Ser Thr Gln Cys Cys Pro Gly Ser
                 335                 340                 345

 Pro Val Ala Gln Thr Glu Ser Pro Cys Asp Leu Ser Ser Ile Val
                 350                 355                 360

 Glu Glu Glu Asn Thr Asp Arg Ser Cys Arg Lys Lys Asn Lys Gly
                 365                 370                 375

 Val Glu Arg Lys Gly Glu Glu Val Glu Pro Ala Pro Ile Val Asp
                 380                 385                 390

 Ser Gly Thr Val Ser Asp Gln Asp Ser Cys Leu Gln Ser Leu Pro
                 395                 400                 405

 Asp Cys Gly Val Lys Gly Thr Glu Gly Leu Ser Ser Cys Gly Asn
                 410                 415                 420

 Arg Asn Glu Glu Thr Gly Thr Lys Ser Ser Gly Met Pro Thr Asp
                 425                 430                 435

 Gln Glu Ser Leu Ser Ser Gly Asp Ala Val Leu Gln Arg Asp Leu
                 440                 445                 450

 Val Met Glu Pro Gly Thr Ala Gln Tyr Ser Ser Gly Gly Glu Leu
                 455                 460                 465

 Gly Gly Ile Ser Thr Thr Asn Val Ser Thr Pro Asp Thr Ala Gly
                 470                 475                 480

 Glu Met Glu His Gly Leu Met Asn Pro Asp Ala Thr Val Trp Lys
                 485                 490                 495

 Asn Val Leu Gln Gly Gly Glu Ser Thr Lys Glu Arg Phe Glu Asn
                 500                 505                 510

 Ser Asn Ile Gly Thr Ala Gly Ala Ser Asp Val His Val Thr Ser
                 515                 520                 525

 Lys Pro Val Asp Lys Ile Ser Val Pro Asn Cys Ala Pro Ala Ala
                 530                 535                 540

 Ser Ser Leu Asp Gly Asn Lys Pro Ala Glu Ser Ser Leu Ala Phe
                 545                 550                 555

 Ser Asn Glu Glu Thr Ser Thr Glu Lys Thr Ala Glu Thr Glu Thr
                 560                 565                 570

 Ser Arg Ser Arg Glu Glu Ser Ala Asp Ala Pro Val Asp Gln Asn
                 575                 580                 585

 Ser Val Val Ile Pro Ala Ala Ala Lys Asp Lys Ile Ser Asp Gly
                 590                 595                 600

 Leu Glu Pro Tyr Thr Leu Leu Ala Ala Gly Ile Gly Glu Ala Met
                 605                 610                 615

 Ser Pro Ser Asp Leu Ala Leu Leu Gly Leu Glu Glu Asp Val Met
                 620                 625                 630

 Pro His Gln Asn Ser Glu Thr Asn Ser Ser His Ala Gln Ser Gln
                 635                 640                 645

 Lys Gly Lys Ser Ser Pro Ile Cys Ser Thr Thr Gly Asp Asp Lys
                 650                 655                 660

 Leu Cys Ala Asp Ser Ala Cys Gln Gln Asn Thr Val Thr Ser Ser
                 665                 670                 675

 Gly Asp Leu Val Ala Lys Leu Cys Asp Asn Ile Val Ser Glu Ser
                 680                 685                 690

 Glu Ser Thr Thr Ala Arg Gln Pro Ser Ser Gln Asp Pro Pro Asp
                 695                 700                 705

 Ala Ser His Cys Glu Asp Pro Gln Ala His Thr Val Thr Ser Asp
                 710                 715                 720

 Pro Val Arg Asp Thr Gln Glu Arg Ala Asp Phe Cys Pro Phe Lys
                 725                 730                 735

 Val Val Asp Asn Lys Gly Gln Arg Lys Asp Val Lys Leu Asp Lys
                 740                 745                 750

 Pro Leu Thr Asn Met Leu Glu Val Val Ser His Pro His Pro Val
                 755                 760                 765

 Val Pro Lys Met Glu Lys Glu Leu Val Pro Asp Gln Ala Val Ile
                 770                 775                 780

 Ser Asp Ser Thr Phe Ser Leu Ala Asn Ser Pro Gly Ser Glu Ser
                 785                 790                 795

 Val Thr Lys Asp Asp Ala Leu Ser Phe Val Pro Ser Gln Lys Glu
                 800                 805                 810

 Lys Gly Thr Ala Thr Pro Glu Leu His Thr Ala Thr Asp Tyr Arg
                 815                 820                 825

 Asp Gly Pro Asp Gly Asn Ser Asn Glu Pro Asp Thr Arg Pro Leu
                 830                 835                 840

 Glu Asp Arg Ala Val Gly Leu Ser Thr Ser Ser Thr Ala Ala Glu
                 845                 850                 855

 Leu Gln His Gly Met Gly Asn Thr Ser Leu Thr Gly Leu Gly Gly
                 860                 865                 870

 Glu His Glu Gly Pro Ala Pro Pro Ala Ile Pro Glu Ala Leu Asn
                 875                 880                 885

 Ile Lys Gly Asn Thr Asp Ser Ser Leu Gln Ser Val Gly Lys Ala
                 890                 895                 900

 Thr Leu Ala Leu Asp Ser Val Leu Thr Glu Glu Gly Lys Leu Leu
                 905                 910                 915

 Val Val Ser Glu Ser Ser Ala Ala Gln Glu Gln Asp Lys Asp Lys
                 920                 925                 930

 Ala Val Thr Cys Ser Ser Ile Lys Glu Asn Ala Leu Ser Ser Gly
                 935                 940                 945

 Thr Leu Gln Glu Glu Gln Arg Thr Pro Pro Pro Gly Gln Asp Thr
                 950                 955                 960

 Gln Gln Phe His Glu Lys Ser Ile Ser Ala Asp Cys Ala Lys Asp
                 965                 970                 975

 Lys Ala Leu Gln Leu Ser Asn Ser Pro Gly Ala Ser Ser Ala Phe
                 980                 985                 990

 Leu Lys Ala Glu Thr Glu His Asn Lys Glu Val Ala Pro Gln Val
                 995                1000                1005

 Ser Leu Leu Thr Gln Gly Gly Ala Ala Gln Ser Leu Val Pro Pro
                1010                1015                1020

 Gly Ala Ser Leu Ala Thr Glu Ser Arg Gln Glu Ala Leu Gly Ala
                1025                1030                1035

 Glu His Asn Ser Ser Ala Leu Leu Pro Cys Leu Leu Pro Asp Gly
                1040                1045                1050

 Ser Asp Gly Ser Asp Ala Leu Asn Cys Ser Gln Pro Ser Pro Leu
                1055                1060                1065

 Asp Val Gly Val Lys Asn Thr Gln Ser Gln Gly Lys Thr Ser Ala
                1070                1075                1080

 Cys Glu Val Ser Gly Asp Val Thr Val Asp Val Thr Gly Val Asn
                1085                1090                1095

 Ala Leu Gln Gly Met Ala Glu Pro Arg Arg Glu Asn Ile Ser His
                1100                1105                1110

 Asn Thr Gln Asp Ile Leu Ile Pro Asn Val Leu Leu Ser Gln Glu
                1115                1120                1125

 Lys Asn Ala Val Leu Gly Leu Pro Val Ala Leu Gln Asp Lys Ala
                1130                1135                1140

 Val Thr Asp Pro Gln Gly Val Gly Thr Pro Glu Met Ile Pro Leu
                1145                1150                1155

 Asp Trp Glu Lys Gly Lys Leu Glu Gly Ala Asp His Ser Cys Thr
                1160                1165                1170

 Met Gly Asp Ala Glu Glu Ala Gln Ile Asp Asp Glu Ala His Pro
                1175                1180                1185

 Val Leu Leu Gln Pro Val Ala Lys Glu Leu Pro Thr Asp Met Glu
                1190                1195                1200

 Leu Ser Ala His Asp Asp Gly Ala Pro Ala Gly Val Arg Glu Val
                1205                1210                1215

 Met Arg Ala Pro Pro Ser Gly Arg Glu Arg Ser Thr Pro Ser Leu
                1220                1225                1230

 Pro Cys Met Val Ser Ala Gln Asp Ala Pro Leu Pro Lys Gly Ala
                1235                1240                1245

 Asp Leu Ile Glu Glu Ala Ala Ser Arg Ile Val Asp Ala Val Ile
                1250                1255                1260

 Glu Gln Val Lys Ala Ala Gly Ala Leu Leu Thr Glu Gly Glu Ala
                1265                1270                1275

 Cys His Met Ser Leu Ser Ser Pro Glu Leu Gly Pro Leu Thr Lys
                1280                1285                1290

 Gly Leu Glu Ser Ala Phe Thr Glu Lys Val Ser Thr Phe Pro Pro
                1295                1300                1305

 Gly Glu Ser Leu Pro Met Gly Ser Thr Pro Glu Glu Ala Thr Gly
                1310                1315                1320

 Ser Leu Ala Gly Cys Phe Ala Gly Arg Glu Glu Pro Glu Lys Ile
                1325                1330                1335

 Ile Leu Pro Val Gln Gly Pro Glu Pro Ala Ala Glu Met Pro Asp
                1340                1345                1350

 Val Lys Ala Glu Asp Glu Val Asp Phe Arg Ala Ser Ser Ile Ser
                1355                1360                1365

 Glu Glu Val Ala Val Gly Ser Ile Ala Ala Thr Leu Lys Met Lys
                1370                1375                1380

 Gln Gly Pro Met Thr Gln Ala Ile Asn Arg Glu Asn Trp Cys Thr
                1385                1390                1395

 Ile Glu Pro Cys Pro Asp Ala Ala Ser Leu Leu Ala Ser Lys Gln
                1400                1405                1410

 Ser Pro Glu Cys Glu Asn Phe Leu Asp Val Gly Leu Gly Arg Glu
                1415                1420                1425

 Cys Thr Ser Lys Gln Gly Val Leu Lys Arg Glu Ser Gly Ser Asp
                1430                1435                1440

 Ser Asp Leu Phe His Ser Pro Ser Asp Asp Met Asp Ser Ile Ile
                1445                1450                1455

 Phe Pro Lys Pro Glu Glu Glu His Leu Ala Cys Asp Ile Thr Gly
                1460                1465                1470

 Ser Ser Ser Ser Thr Asp Asp Thr Ala Ser Leu Asp Arg His Ser
                1475                1480                1485

 Ser His Gly Ser Asp Val Ser Leu Ser Gln Ile Leu Lys Pro Asn
                1490                1495                1500

 Arg Ser Arg Asp Arg Gln Ser Leu Asp Gly Phe Tyr Ser His Gly
                1505                1510                1515

 Met Gly Ala Glu Gly Arg Glu Ser Glu Ser Glu Pro Ala Asp Pro
                1520                1525                1530

 Gly Asp Val Glu Glu Glu Glu Met Asp Ser Ile Thr Glu Val Pro
                1535                1540                1545

 Ala Asn Cys Ser Val Leu Arg Ser Ser Met Arg Ser Leu Ser Pro
                1550                1555                1560

 Phe Arg Arg His Ser Trp Gly Pro Gly Lys Asn Ala Ala Ser Asp
                1565                1570                1575

 Ala Glu Met Asn His Arg Ser Met Ser Trp Cys Pro Ser Gly Val
                1580                1585                1590

 Gln Tyr Ser Ala Gly Leu Ser Ala Asp Phe Asn Tyr Arg Ser Phe
                1595                1600                1605

 Ser Leu Glu Gly Leu Thr Gly Gly Ala Gly Val Gly Asn Lys Pro
                1610                1615                1620

 Ser Ser Ser Leu Glu Val Ser Ser Ala Asn Ala Glu Glu Leu Arg
                1625                1630                1635

 His Pro Phe Ser Gly Glu Glu Arg Val Asp Ser Leu Val Ser Leu
                1640                1645                1650

 Ser Glu Glu Asp Leu Glu Ser Asp Gln Arg Glu His Arg Met Phe
                1655                1660                1665

 Asp Gln Gln Ile Cys His Arg Ser Lys Gln Gln Gly Phe Asn Tyr
                1670                1675                1680

 Cys Thr Ser Ala Ile Ser Ser Pro Leu Thr Lys Ser Ile Ser Leu
                1685                1690                1695

 Met Thr Ile Ser His Pro Gly Leu Asp Asn Ser Arg Pro Phe His
                1700                1705                1710

 Ser Thr Phe His Asn Thr Ser Ala Asn Leu Thr Glu Ser Ile Thr
                1715                1720                1725

 Glu Glu Asn Tyr Asn Phe Leu Pro His Ser Pro Ser Lys Lys Asp
                1730                1735                1740

 Ser Glu Trp Lys Ser Gly Thr Lys Val Ser Arg Thr Phe Ser Tyr
                1745                1750                1755

 Ile Lys Asn Lys Met Ser Ser Ser Lys Lys Ser Lys Glu Lys Glu
                1760                1765                1770

 Lys Glu Lys Asp Lys Ile Lys Glu Lys Glu Lys Asp Ser Lys Asp
                1775                1780                1785

 Lys Glu Lys Asp Lys Lys Thr Val Asn Gly His Thr Phe Ser Ser
                1790                1795                1800

 Ile Pro Val Val Gly Pro Ile Ser Cys Ser Gln Cys Met Lys Pro
                1805                1810                1815

 Phe Thr Asn Lys Asp Ala Tyr Thr Cys Ala Asn Cys Ser Ala Phe
                1820                1825                1830

 Val His Lys Gly Cys Arg Glu Ser Leu Ala Ser Cys Ala Lys Val
                1835                1840                1845

 Lys Met Lys Gln Pro Lys Gly Ser Leu Gln Ala His Asp Thr Ser
                1850                1855                1860

 Ser Leu Pro Thr Val Ile Met Arg Asn Lys Pro Ser Gln Pro Lys
                1865                1870                1875

 Glu Arg Pro Arg Ser Ala Val Leu Leu Val Asp Glu Thr Ala Thr
                1880                1885                1890

 Thr Pro Ile Phe Ala Asn Arg Arg Ser Gln Gln Ser Val Ser Leu
                1895                1900                1905

 Ser Lys Ser Val Ser Ile Gln Asn Ile Thr Gly Val Gly Asn Asp
                1910                1915                1920

 Glu Asn Met Ser Asn Thr Trp Lys Phe Leu Ser His Ser Thr Asp
                1925                1930                1935

 Ser Leu Asn Lys Ile Ser Lys Val Asn Glu Ser Thr Glu Ser Leu
                1940                1945                1950

 Thr Asp Glu Gly Val Gly Thr Asp Met Asn Glu Gly Gln Leu Leu
                1955                1960                1965

 Gly Asp Phe Glu Ile Glu Ser Lys Gln Leu Glu Ala Glu Ser Trp
                1970                1975                1980

 Ser Arg Ile Ile Asp Ser Lys Phe Leu Lys Gln Gln Lys Lys Asp
                1985                1990                1995

 Val Val Lys Arg Gln
                2000

<210> 1747
<211> 3113
<212> DNA
<213> Homo sapien

<400> 1747
 aaaaagtaca gagtccaggg aaaagacttg cttgtaactt tatgaattct 50

 ggattttttt ttttcctttg ctttttctta actttcacta agggttactg 100

 tagtctgatg tgtccttccc aaggccacga aatttgacaa gctgcacttt 150

 tcttttgctc aatgatttct gctttaagcc aaagaactgc ctataatttc 200

 actaagaatg tcttctaatt cagatactgg ggatttacaa gagtctttaa 250

 agcacggact tacacctatt gtgtctcaat ttaaaatggt gaattactcc 300

 tatgatgaag atctggaaga gctttgtccc gtgtgtggag ataaagtgtc 350

 tgggtaccat tatgggctcc tcacctgtga aagctgcaag ggatttttta 400

 agcgaacagt ccaaaataat aaaaggtaca catgtataga aaaccagaac 450

 tgccaaattg acaaaacaca gagaaagcgt tgtccttact gtcgttttca 500

 aaaatgtcta agtgttggaa tgaagctaga agctgtaagg gccgaccgaa 550

 tgcgtggagg aaggaataag tttgggccaa tgtacaagag agacagggcc 600

 ctgaagcaac agaaaaaagc cctcatccga gccaatggac ttaagctaga 650

 agccatgtct caggtgatcc aagctatgcc ctctgacctg accatttcct 700

 ctgcaattca aaacatccac tctgcctcca aaggcctacc tctgaaccat 750

 gctgccttgc ctcctacaga ctatgacaga agtccctttg taacatcccc 800

 cattagcatg acaatgcccc ctcacggcag cctgcaaggt taccaaacat 850

 atggccactt tcctagccgg gccatcaagt ctgagtaccc agacccctat 900

 accagctcac ccgagtccat aatgggctat tcatatatgg atagttacca 950

 gacgagctct ccagcaagca tcccacatct gatactggaa cttttgaagt 1000

 gtgagccaga tgagcctcaa gtccaggcta aaatcatggc ctatttgcag 1050

 caagagcagg ctaaccgaag caagcacgaa aagctgagca cctttgggct 1100

 tatgtgcaaa atggcagatc aaactctctt ctccattgtc gagtgggcca 1150

 ggagtagtat cttcttcaga gaacttaagg ttgatgacca aatgaagctg 1200

 cttcagaact gctggagtga gctcttaatc ctcgaccaca tttaccgaca 1250

 agtggtacat ggaaaggaag gatccatctt cctggttact gggcaacaag 1300

 tggactattc cataatagca tcacaagccg gagccaccct caacaacctc 1350

 atgagtcatg cacaggagtt agtggcaaaa cttcgttctc tccagtttga 1400

 tcaacgagag ttcgtatgtc tgaaattctt ggtgctcttt agtttagatg 1450

 tcaaaaacct tgaaaacttc cagctggtag aaggtgtcca ggaacaagtc 1500

 aatgccgccc tgctggacta cacaatgtgt aactacccgc agcagacaga 1550

 gaaatttgga cagctacttc ttcgactacc cgaaatccgg gccatcagta 1600

 tgcaggctga agaatacctc tactacaagc acctgaacgg ggatgtgccc 1650

 tataataacc ttctcattga aatgttgcat gccaaaagag cataagttac 1700

 aacccctagg agctctgctt tcaaaacaaa aagagattgg gggagtgggg 1750

 agggggaaga agaacaggaa gaaaaaaagt actctgaact gctccaagca 1800

 acgctaatta aaaacttgct ttaaagatat tgaatttaaa aaggcataat 1850

 aatcaaatac ttaatagcaa ataaatgatg tatcagggta tttgtattgc 1900

 aaactgtgaa tcaaaggctt cacagcccca gaggattcca tataaaagac 1950

 attgtaatgg agtggattga actcacagat ggataccaac acggtcagaa 2000

 gaaaaacgga cagaacggtt cttgtatatt taaactgatc tccactatga 2050

 agaaatttag gaactaatct tattaattag gcttatacag cgggggattt 2100

 gagcttacag gattcctcca tggtaaagct gaactgaaac aattctcaag 2150

 aatgcatcag ctgtacctac aatagcccct ccctcttcct ttgaaggccc 2200

 gagcacctct gccctgtggt caccgaatct gtactaagga cctgtgttca 2250

 gccacaccca gtggtagctc caccaaatca tgaacagcct aattttgagt 2300

 gtctgtgtct tagacctgca aacagctaat aggaaattct attaatatgt 2350

 tagcttgcca ttttaaatat gttctgaggg ttgttttgtc tcgtgttcat 2400

 gatgttaaga aaatgcaggc agtatccctc atcttatgta agtgtgaatt 2450

 aatattaagg gaaatgacta caaactttca aagcaaatgc tccatagcta 2500

 aagcaactta gaccttattt ctgctactgt tgctgaaatg tggctttggc 2550

 attgttggat ttcataaaaa atttctggca ggaagtcttg ttagtataca 2600

 tcagtctttt tcatcatcca agtttgtagt tcatttaaaa atacaacatt 2650

 aaacacattt tgctaggatg tcaaatagtc acagttctaa gtagttggaa 2700

 acaaaattga cgcatgttaa tctatgcaaa gagaaaggaa aggatgaggt 2750

 gatgtattga ctcaaggttc attcttgctg caattgaaca tcctcaagag 2800

 ttgggatgga aatggtgatt tttacatgtg tcctggaaag atattaaagt 2850

 aattcaaatc ttccccaaag gggaaaggaa gagagtgata ctgacctttt 2900

 taagtcatag accaaagtct gctgtagaac aaatatggga ggacaaagaa 2950

 tcgcaaattc ttcaaatgac tattatcagt attattaaca tgcgatgcca 3000

 caggtatgaa agtcttgcct tatttcacaa ttttaaaagg tagctgtgca 3050

 gatgtggatc aacatttgtt taaaataaag tattaatact ttaaagtcaa 3100

 aaaaaaaaaa aaa 3113

<210> 1748
<211> 495
<212> PRT
<213> Homo sapien

<400> 1748
 Met Ser Ser Asn Ser Asp Thr Gly Asp Leu Gln Glu Ser Leu Lys
   1               5                  10                  15

 His Gly Leu Thr Pro Ile Val Ser Gln Phe Lys Met Val Asn Tyr
                  20                  25                  30

 Ser Tyr Asp Glu Asp Leu Glu Glu Leu Cys Pro Val Cys Gly Asp
                  35                  40                  45

 Lys Val Ser Gly Tyr His Tyr Gly Leu Leu Thr Cys Glu Ser Cys
                  50                  55                  60

 Lys Gly Phe Phe Lys Arg Thr Val Gln Asn Asn Lys Arg Tyr Thr
                  65                  70                  75

 Cys Ile Glu Asn Gln Asn Cys Gln Ile Asp Lys Thr Gln Arg Lys
                  80                  85                  90

 Arg Cys Pro Tyr Cys Arg Phe Gln Lys Cys Leu Ser Val Gly Met
                  95                 100                 105

 Lys Leu Glu Ala Val Arg Ala Asp Arg Met Arg Gly Gly Arg Asn
                 110                 115                 120

 Lys Phe Gly Pro Met Tyr Lys Arg Asp Arg Ala Leu Lys Gln Gln
                 125                 130                 135

 Lys Lys Ala Leu Ile Arg Ala Asn Gly Leu Lys Leu Glu Ala Met
                 140                 145                 150

 Ser Gln Val Ile Gln Ala Met Pro Ser Asp Leu Thr Ile Ser Ser
                 155                 160                 165

 Ala Ile Gln Asn Ile His Ser Ala Ser Lys Gly Leu Pro Leu Asn
                 170                 175                 180

 His Ala Ala Leu Pro Pro Thr Asp Tyr Asp Arg Ser Pro Phe Val
                 185                 190                 195

 Thr Ser Pro Ile Ser Met Thr Met Pro Pro His Gly Ser Leu Gln
                 200                 205                 210

 Gly Tyr Gln Thr Tyr Gly His Phe Pro Ser Arg Ala Ile Lys Ser
                 215                 220                 225

 Glu Tyr Pro Asp Pro Tyr Thr Ser Ser Pro Glu Ser Ile Met Gly
                 230                 235                 240

 Tyr Ser Tyr Met Asp Ser Tyr Gln Thr Ser Ser Pro Ala Ser Ile
                 245                 250                 255

 Pro His Leu Ile Leu Glu Leu Leu Lys Cys Glu Pro Asp Glu Pro
                 260                 265                 270

 Gln Val Gln Ala Lys Ile Met Ala Tyr Leu Gln Gln Glu Gln Ala
                 275                 280                 285

 Asn Arg Ser Lys His Glu Lys Leu Ser Thr Phe Gly Leu Met Cys
                 290                 295                 300

 Lys Met Ala Asp Gln Thr Leu Phe Ser Ile Val Glu Trp Ala Arg
                 305                 310                 315

 Ser Ser Ile Phe Phe Arg Glu Leu Lys Val Asp Asp Gln Met Lys
                 320                 325                 330

 Leu Leu Gln Asn Cys Trp Ser Glu Leu Leu Ile Leu Asp His Ile
                 335                 340                 345

 Tyr Arg Gln Val Val His Gly Lys Glu Gly Ser Ile Phe Leu Val
                 350                 355                 360

 Thr Gly Gln Gln Val Asp Tyr Ser Ile Ile Ala Ser Gln Ala Gly
                 365                 370                 375

 Ala Thr Leu Asn Asn Leu Met Ser His Ala Gln Glu Leu Val Ala
                 380                 385                 390

 Lys Leu Arg Ser Leu Gln Phe Asp Gln Arg Glu Phe Val Cys Leu
                 395                 400                 405

 Lys Phe Leu Val Leu Phe Ser Leu Asp Val Lys Asn Leu Glu Asn
                 410                 415                 420

 Phe Gln Leu Val Glu Gly Val Gln Glu Gln Val Asn Ala Ala Leu
                 425                 430                 435

 Leu Asp Tyr Thr Met Cys Asn Tyr Pro Gln Gln Thr Glu Lys Phe
                 440                 445                 450

 Gly Gln Leu Leu Leu Arg Leu Pro Glu Ile Arg Ala Ile Ser Met
                 455                 460                 465

 Gln Ala Glu Glu Tyr Leu Tyr Tyr Lys His Leu Asn Gly Asp Val
                 470                 475                 480

 Pro Tyr Asn Asn Leu Leu Ile Glu Met Leu His Ala Lys Arg Ala
                 485                 490                 495

<210> 1749
<211> 3113
<212> DNA
<213> Homo sapien

<400> 1749
 aaaaagtaca gagtccaggg aaaagacttg cttgtaactt tatgaattct 50

 ggattttttt ttttcctttg ctttttctta actttcacta agggttactg 100

 tagtctgatg tgtccttccc aaggccacga aatttgacaa gctgcacttt 150

 tcttttgctc aatgatttct gctttaagcc aaagaactgc ctataatttc 200

 actaagaatg tcttctaatt cagatactgg ggatttacaa gagtctttaa 250

 agcacggact tacacctatt gtgtctcaat ttaaaatggt gaattactcc 300

 tatgatgaag atctggaaga gctttgtccc gtgtgtggag ataaagtgtc 350

 tgggtaccat tatgggctcc tcacctgtga aagctgcaag ggatttttta 400

 agcgaacagt ccaaaataat aaaaggtaca catgtataga aaaccagaac 450

 tgccaaattg acaaaacaca gagaaagcgt tgtccttact gtcgttttca 500

 aaaatgtcta agtgttggaa tgaagctaga agctgtaagg gccgaccgaa 550

 tgcgtggagg aaggaataag tttgggccaa tgtacaagag agacagggcc 600

 ctgaagcaac agaaaaaagc cctcatccga gccaatggac ttaagctaga 650

 agccatgtct caggtgatcc aagctatgcc ctctgacctg accatttcct 700

 ctgcaattca aaacatccac tctgcctcca aaggcctacc tctgaaccat 750

 gctgccttgc ctcctacaga ctatgacaga agtccctttg taacatcccc 800

 cattagcatg acaatgcccc ctcacggcag cctgcaaggt taccaaacat 850

 atggccactt tcctagccgg gccatcaagt ctgagtaccc agacccctat 900

 accagctcac ccgagtccat aatgggctat tcatatatgg atagttacca 950

 gacgagctct ccagcaagca tcccacatct gatactggaa cttttgaagt 1000

 gtgagccaga tgagcctcaa gtccaggcta aaatcatggc ctatttgcag 1050

 caagagcagg ctaaccgaag caagcacgaa aagctgagca cctttgggct 1100

 tatgtgcaaa atggcagatc aaactctctt ctccattgtc gagtgggcca 1150

 ggagtagtat cttcttcaga gaacttaagg ttgatgacca aatgaagctg 1200

 cttcagaact gctggagtga gctcttaatc ctcgaccaca tttaccgaca 1250

 agtggtacat ggaaaggaag gatccatctt cctggttact gggcaacaag 1300

 tggactattc cataatagca tcacaagccg gagccaccct caacaacctc 1350

 atgagtcatg cacaggagtt agtggcaaaa cttcgttctc tccagtttga 1400

 tcaacgagag ttcgtatgtc tgaaattctt ggtgctcttt agtttagatg 1450

 tcaaaaacct tgaaaacttc cagctggtag aaggtgtcca ggaacaagtc 1500

 aatgccgccc tgctggacta cacaatgtgt aactacccgc agcagacaga 1550

 gaaatttgga cagctacttc ttcgactacc cgaaatccgg gccatcagta 1600

 tgcaggctga agaatacctc tactacaagc acctgaacgg ggatgtgccc 1650

 tataataacc ttctcattga aatgttgcat gccaaaagag cataagttac 1700

 aacccctagg agctctgctt tcaaaacaaa aagagattgg gggagtgggg 1750

 agggggaaga agaacaggaa gaaaaaaagt actctgaact gctccaagca 1800

 acgctaatta aaaacttgct ttaaagatat tgaatttaaa aaggcataat 1850

 aatcaaatac ttaatagcaa ataaatgatg tatcagggta tttgtattgc 1900

 aaactgtgaa tcaaaggctt cacagcccca gaggattcca tataaaagac 1950

 attgtaatgg agtggattga actcacagat ggataccaac acggtcagaa 2000

 gaaaaacgga cagaacggtt cttgtatatt taaactgatc tccactatga 2050

 agaaatttag gaactaatct tattaattag gcttatacag cgggggattt 2100

 gagcttacag gattcctcca tggtaaagct gaactgaaac aattctcaag 2150

 aatgcatcag ctgtacctac aatagcccct ccctcttcct ttgaaggccc 2200

 gagcacctct gccctgtggt caccgaatct gtactaagga cctgtgttca 2250

 gccacaccca gtggtagctc caccaaatca tgaacagcct aattttgagt 2300

 gtctgtgtct tagacctgca aacagctaat aggaaattct attaatatgt 2350

 tagcttgcca ttttaaatat gttctgaggg ttgttttgtc tcgtgttcat 2400

 gatgttaaga aaatgcaggc agtatccctc atcttatgta agtgtgaatt 2450

 aatattaagg gaaatgacta caaactttca aagcaaatgc tccatagcta 2500

 aagcaactta gaccttattt ctgctactgt tgctgaaatg tggctttggc 2550

 attgttggat ttcataaaaa atttctggca ggaagtcttg ttagtataca 2600

 tcagtctttt tcatcatcca agtttgtagt tcatttaaaa atacaacatt 2650

 aaacacattt tgctaggatg tcaaatagtc acagttctaa gtagttggaa 2700

 acaaaattga cgcatgttaa tctatgcaaa gagaaaggaa aggatgaggt 2750

 gatgtattga ctcaaggttc attcttgctg caattgaaca tcctcaagag 2800

 ttgggatgga aatggtgatt tttacatgtg tcctggaaag atattaaagt 2850

 aattcaaatc ttccccaaag gggaaaggaa gagagtgata ctgacctttt 2900

 taagtcatag accaaagtct gctgtagaac aaatatggga ggacaaagaa 2950

 tcgcaaattc ttcaaatgac tattatcagt attattaaca tgcgatgcca 3000

 caggtatgaa agtcttgcct tatttcacaa ttttaaaagg tagctgtgca 3050

 gatgtggatc aacatttgtt taaaataaag tattaatact ttaaagtcaa 3100

 aaaaaaaaaa aaa 3113

<210> 1750
<211> 495
<212> PRT
<213> Homo sapien

<400> 1750
 Met Ser Ser Asn Ser Asp Thr Gly Asp Leu Gln Glu Ser Leu Lys
   1               5                  10                  15

 His Gly Leu Thr Pro Ile Val Ser Gln Phe Lys Met Val Asn Tyr
                  20                  25                  30

 Ser Tyr Asp Glu Asp Leu Glu Glu Leu Cys Pro Val Cys Gly Asp
                  35                  40                  45

 Lys Val Ser Gly Tyr His Tyr Gly Leu Leu Thr Cys Glu Ser Cys
                  50                  55                  60

 Lys Gly Phe Phe Lys Arg Thr Val Gln Asn Asn Lys Arg Tyr Thr
                  65                  70                  75

 Cys Ile Glu Asn Gln Asn Cys Gln Ile Asp Lys Thr Gln Arg Lys
                  80                  85                  90

 Arg Cys Pro Tyr Cys Arg Phe Gln Lys Cys Leu Ser Val Gly Met
                  95                 100                 105

 Lys Leu Glu Ala Val Arg Ala Asp Arg Met Arg Gly Gly Arg Asn
                 110                 115                 120

 Lys Phe Gly Pro Met Tyr Lys Arg Asp Arg Ala Leu Lys Gln Gln
                 125                 130                 135

 Lys Lys Ala Leu Ile Arg Ala Asn Gly Leu Lys Leu Glu Ala Met
                 140                 145                 150

 Ser Gln Val Ile Gln Ala Met Pro Ser Asp Leu Thr Ile Ser Ser
                 155                 160                 165

 Ala Ile Gln Asn Ile His Ser Ala Ser Lys Gly Leu Pro Leu Asn
                 170                 175                 180

 His Ala Ala Leu Pro Pro Thr Asp Tyr Asp Arg Ser Pro Phe Val
                 185                 190                 195

 Thr Ser Pro Ile Ser Met Thr Met Pro Pro His Gly Ser Leu Gln
                 200                 205                 210

 Gly Tyr Gln Thr Tyr Gly His Phe Pro Ser Arg Ala Ile Lys Ser
                 215                 220                 225

 Glu Tyr Pro Asp Pro Tyr Thr Ser Ser Pro Glu Ser Ile Met Gly
                 230                 235                 240

 Tyr Ser Tyr Met Asp Ser Tyr Gln Thr Ser Ser Pro Ala Ser Ile
                 245                 250                 255

 Pro His Leu Ile Leu Glu Leu Leu Lys Cys Glu Pro Asp Glu Pro
                 260                 265                 270

 Gln Val Gln Ala Lys Ile Met Ala Tyr Leu Gln Gln Glu Gln Ala
                 275                 280                 285

 Asn Arg Ser Lys His Glu Lys Leu Ser Thr Phe Gly Leu Met Cys
                 290                 295                 300

 Lys Met Ala Asp Gln Thr Leu Phe Ser Ile Val Glu Trp Ala Arg
                 305                 310                 315

 Ser Ser Ile Phe Phe Arg Glu Leu Lys Val Asp Asp Gln Met Lys
                 320                 325                 330

 Leu Leu Gln Asn Cys Trp Ser Glu Leu Leu Ile Leu Asp His Ile
                 335                 340                 345

 Tyr Arg Gln Val Val His Gly Lys Glu Gly Ser Ile Phe Leu Val
                 350                 355                 360

 Thr Gly Gln Gln Val Asp Tyr Ser Ile Ile Ala Ser Gln Ala Gly
                 365                 370                 375

 Ala Thr Leu Asn Asn Leu Met Ser His Ala Gln Glu Leu Val Ala
                 380                 385                 390

 Lys Leu Arg Ser Leu Gln Phe Asp Gln Arg Glu Phe Val Cys Leu
                 395                 400                 405

 Lys Phe Leu Val Leu Phe Ser Leu Asp Val Lys Asn Leu Glu Asn
                 410                 415                 420

 Phe Gln Leu Val Glu Gly Val Gln Glu Gln Val Asn Ala Ala Leu
                 425                 430                 435

 Leu Asp Tyr Thr Met Cys Asn Tyr Pro Gln Gln Thr Glu Lys Phe
                 440                 445                 450

 Gly Gln Leu Leu Leu Arg Leu Pro Glu Ile Arg Ala Ile Ser Met
                 455                 460                 465

 Gln Ala Glu Glu Tyr Leu Tyr Tyr Lys His Leu Asn Gly Asp Val
                 470                 475                 480

 Pro Tyr Asn Asn Leu Leu Ile Glu Met Leu His Ala Lys Arg Ala
                 485                 490                 495

<210> 1751
<211> 2934
<212> DNA
<213> Homo sapien

<400> 1751
 gcccctccct ccgcccgccc gccggcccgc ccgtcagtct ggcaggcagg 50

 caggcaatcg gtccgagtgg ctgtcggctc ttcagctctc ccgctcggcg 100

 tcttccttcc tcctcccggt cagcgtcggc ggctgcaccg gcggcggcgc 150

 agtccctgcg ggaggggcga caagagctga gcggcggccg ccgagcgtcg 200

 agctcagcgc ggcggaggcg gcggcggccc ggcagccaac atggcggcgg 250

 cggcggcggc gggcgcgggc ccggagatgg tccgcgggca ggtgttcgac 300

 gtggggccgc gctacaccaa cctctcgtac atcggcgagg gcgcctacgg 350

 catggtgtgc tctgcttatg ataatgtcaa caaagttcga gtagctatca 400

 agaaaatcag cccctttgag caccagacct actgccagag aaccctgagg 450

 gagataaaaa tcttactgcg cttcagacat gagaacatca ttggaatcaa 500

 tgacattatt cgagcaccaa ccatcgagca aatgaaagat gtatatatag 550

 tacaggacct catggaaaca gatctttaca agctcttgaa gacacaacac 600

 ctcagcaatg accatatctg ctattttctc taccagatcc tcagagggtt 650

 aaaatatatc cattcagcta acgttctgca ccgtgacctc aagccttcca 700

 acctgctgct caacaccacc tgtgatctca agatctgtga ctttggcctg 750

 gcccgtgttg cagatccaga ccatgatcac acagggttcc tgacagaata 800

 tgtggccaca cgttggtaca gggctccaga aattatgttg aattccaagg 850

 gctacaccaa gtccattgat atttggtctg taggctgcat tctggcagaa 900

 atgctttcta acaggcccat ctttccaggg aagcattatc ttgaccagct 950

 gaaacacatt ttgggtattc ttggatcccc atcacaagaa gacctgaatt 1000

 gtataataaa tttaaaagct aggaactatt tgctttctct tccacacaaa 1050

 aataaggtgc catggaacag gctgttccca aatgctgact ccaaagctct 1100

 ggacttattg gacaaaatgt tgacattcaa cccacacaag aggattgaag 1150

 tagaacaggc tctggcccac ccatatctgg agcagtatta cgacccgagt 1200

 gacgagccca tcgccgaagc accattcaag ttcgacatgg aattggatga 1250

 cttgcctaag gaaaagctca aagaactaat ttttgaagag actgctagat 1300

 tccagccagg atacagatct taaatttgtc aggacaaggg ctcagaggac 1350

 tggacgtgct cagacatcgg tgttcttctt cccagttctt gacccctggt 1400

 cctgtctcca gcccgtcttg gcttatccac tttgactcct ttgagccgtt 1450

 tggaggggcg gtttctggta gttgtggctt ttatgctttc aaagaatttc 1500

 ttcagtccag agaattcctc ctggcagccc tgtgtgtgtc acccattggt 1550

 gacctgcggc agtatgtact tcagtgcacc ttactgctta ctgttgcttt 1600

 agtcactaat tgctttctgg tttgaaagat gcagtggttc ctccctctcc 1650

 tgaatccttt tctacatgat gccctgctga ccatgcagcc gcaccagaga 1700

 gagattcttc cccaattggc tctagtcact ggcatctcac tttatgatag 1750

 ggaaggctac tacctagggc actttaagtc agtgacagcc ccttatttgc 1800

 acttcacctt ttgaccataa ctgtttcccc agagcaggag cttgtggaaa 1850

 taccttggct gatgttgcag cctgcagcaa gtgcttccgt ctccggaatc 1900

 cttggggagc acttgtccac gtcttttctc atatcatggt agtcactaac 1950

 atatataagg tatgtgctat tggcccagct tttagaaaat gcagtcattt 2000

 ttctaaataa aaaggaagta ctgcacccag cagtgtcact ctgtagttac 2050

 tgtggtcact tgtaccatat agaggtgtaa cacttgtcaa gaagcgttat 2100

 gtgcagtact taatgtttgt aagacttaca aaaaaagatt taaagtggca 2150

 gcttcactcg acatttggtg agagaagtac aaaggttgca gtgctgagct 2200

 gtgggcggtt tctggggatg tcccagggtg gaactccaca tgctggtgca 2250

 tatacgccct tgagctactt caaatgtggt ttatacctcg cagatacaag 2300

 aatctttatg aatatacaat tctttttcct tctacagctt agctccgtct 2350

 tttcaaccac gaacatttaa aacccgacct actagcactg ttctgtcctc 2400

 aagtactcaa atatttctga tactgctgag tcagactgtc agaaaaagct 2450

 agcactaact cgtgtttgga gctctatcca tattttactg atctctttaa 2500

 gtatttgttc ctgccactgt gtactgtgga gttgactcgg tgttctgtcc 2550

 cagtgcggtg cctcctcttg acttccccac tgctctctgt ggtgagaaat 2600

 ttgccttgtt caataattac tgtaccctcg catgactgtt acagctttct 2650

 gtgcagagat gactgtccaa gtgccacatg cctacgattg aaatgaaaac 2700

 tctattgtta cctctgagtt gtgttccacg gaaaatgcta tccagcagat 2750

 catttaggaa aaataattct atttttagct tttcatttct cagctgtcct 2800

 tttttcttgt ttgatttttg acagcaatgg agaatgggtt atataaagac 2850

 tgcctgctaa tatgaacaga aatgcatttg taattcatga aaataaatgt 2900

 acatcttcta tcttcaaaaa aaaaaaaaaa aaaa 2934

<210> 1752
<211> 360
<212> PRT
<213> Homo sapien

<400> 1752
 Met Ala Ala Ala Ala Ala Ala Gly Ala Gly Pro Glu Met Val Arg
   1               5                  10                  15

 Gly Gln Val Phe Asp Val Gly Pro Arg Tyr Thr Asn Leu Ser Tyr
                  20                  25                  30

 Ile Gly Glu Gly Ala Tyr Gly Met Val Cys Ser Ala Tyr Asp Asn
                  35                  40                  45

 Val Asn Lys Val Arg Val Ala Ile Lys Lys Ile Ser Pro Phe Glu
                  50                  55                  60

 His Gln Thr Tyr Cys Gln Arg Thr Leu Arg Glu Ile Lys Ile Leu
                  65                  70                  75

 Leu Arg Phe Arg His Glu Asn Ile Ile Gly Ile Asn Asp Ile Ile
                  80                  85                  90

 Arg Ala Pro Thr Ile Glu Gln Met Lys Asp Val Tyr Ile Val Gln
                  95                 100                 105

 Asp Leu Met Glu Thr Asp Leu Tyr Lys Leu Leu Lys Thr Gln His
                 110                 115                 120

 Leu Ser Asn Asp His Ile Cys Tyr Phe Leu Tyr Gln Ile Leu Arg
                 125                 130                 135

 Gly Leu Lys Tyr Ile His Ser Ala Asn Val Leu His Arg Asp Leu
                 140                 145                 150

 Lys Pro Ser Asn Leu Leu Leu Asn Thr Thr Cys Asp Leu Lys Ile
                 155                 160                 165

 Cys Asp Phe Gly Leu Ala Arg Val Ala Asp Pro Asp His Asp His
                 170                 175                 180

 Thr Gly Phe Leu Thr Glu Tyr Val Ala Thr Arg Trp Tyr Arg Ala
                 185                 190                 195

 Pro Glu Ile Met Leu Asn Ser Lys Gly Tyr Thr Lys Ser Ile Asp
                 200                 205                 210

 Ile Trp Ser Val Gly Cys Ile Leu Ala Glu Met Leu Ser Asn Arg
                 215                 220                 225

 Pro Ile Phe Pro Gly Lys His Tyr Leu Asp Gln Leu Lys His Ile
                 230                 235                 240

 Leu Gly Ile Leu Gly Ser Pro Ser Gln Glu Asp Leu Asn Cys Ile
                 245                 250                 255

 Ile Asn Leu Lys Ala Arg Asn Tyr Leu Leu Ser Leu Pro His Lys
                 260                 265                 270

 Asn Lys Val Pro Trp Asn Arg Leu Phe Pro Asn Ala Asp Ser Lys
                 275                 280                 285

 Ala Leu Asp Leu Leu Asp Lys Met Leu Thr Phe Asn Pro His Lys
                 290                 295                 300

 Arg Ile Glu Val Glu Gln Ala Leu Ala His Pro Tyr Leu Glu Gln
                 305                 310                 315

 Tyr Tyr Asp Pro Ser Asp Glu Pro Ile Ala Glu Ala Pro Phe Lys
                 320                 325                 330

 Phe Asp Met Glu Leu Asp Asp Leu Pro Lys Glu Lys Leu Lys Glu
                 335                 340                 345

 Leu Ile Phe Glu Glu Thr Ala Arg Phe Gln Pro Gly Tyr Arg Ser
                 350                 355                 360

<210> 1753
<211> 984
<212> DNA
<213> Homo sapien

<400> 1753
 actcagggca gagcctggct gctgggcaga agggcacttg ggcgggctgc 50

 ttcagagagg gccattcggt gtcctggccc acagagagag taaacagtga 100

 gagaccaaga gagcaaacca gagagatagg gagggggaat gcaaggggtc 150

 cctgggggac tcaggggtcc cagtggagaa tgagaggcag gccccccgtg 200

 gtgggccggg gacctggctg ccagaggacc gggctggtga ggaggcgagg 250

 atgtggactt tcgtcaccca gctgttggtc acgctggtgc tgctgagctt 300

 cttcctggtc agctgtcaga acgtgatgca cattgtcagg gggtccctgt 350

 gctttgtgct aaagcacatc caccaggagc tggacaagga gctgggggag 400

 agcgagggcc tcagtgacga cgaggagacc atctcaccca gggtggtccg 450

 gcggcgggtc ttcctgaagg ggaatgagtt tcagaatatt ccaggggagc 500

 aggtgacaga ggagcaattc acggatgagc agggcaacat tgtcaccaag 550

 aaggatcaca cctcgacacc caacccctga accccacaca ctctctgcca 600

 tgcacacagg aggagagctg gacctgaggg ccaccgcagc ggtgcacaca 650

 ttcctctggg ctgacggcat gacctctgta agggactcct gctagtcccc 700

 tcttggcatg aatgactgac tgtagacgca tgacctccag gcttcaatcc 750

 tgcctcttgc aatgacagct gatctgtcgg aaccaggaca caaaagcagc 800

 aagaagcggg gagagagagg gatagaaaac aagcgcagga gagcctgcga 850

 acgcaaaagt gaatgagggc tttttgtggc tggggatggg ttttggtttt 900

 ggggtttttt ttttaaattg ttttgacttc gtacagggta ctttttccca 950

 acctcatctg tcagaaatcc atgtgggctt cctg 984

<210> 1754
<211> 109
<212> PRT
<213> Homo sapien

<400> 1754
 Met Trp Thr Phe Val Thr Gln Leu Leu Val Thr Leu Val Leu Leu
   1               5                  10                  15

 Ser Phe Phe Leu Val Ser Cys Gln Asn Val Met His Ile Val Arg
                  20                  25                  30

 Gly Ser Leu Cys Phe Val Leu Lys His Ile His Gln Glu Leu Asp
                  35                  40                  45

 Lys Glu Leu Gly Glu Ser Glu Gly Leu Ser Asp Asp Glu Glu Thr
                  50                  55                  60

 Ile Ser Pro Arg Val Val Arg Arg Arg Val Phe Leu Lys Gly Asn
                  65                  70                  75

 Glu Phe Gln Asn Ile Pro Gly Glu Gln Val Thr Glu Glu Gln Phe
                  80                  85                  90

 Thr Asp Glu Gln Gly Asn Ile Val Thr Lys Lys Asp His Thr Ser
                  95                 100                 105

 Thr Pro Asn Pro


<210> 1755
<211> 2269
<212> DNA
<213> Homo sapien

<400> 1755
 cgccaaaccc tgtggtcaac ggcgcgcggg tctccaggct ccgtgttcta 50

 ggcccgagtt agaatcctgt cagctgagga ggtcgggcgg ggcagagggg 100

 cttcaccttg aaaatctcgg ggagactgtg ggtacgaggg ggaagtgatt 150

 atttttctgt tgcccacttt tcaatatgaa ggaggatcaa gttgtggcgg 200

 aagaaccagg attccaagat gaagaggaat ctttgtttca agatattgac 250

 ctgttacaga aacatggaat taacgtggct gacattaaga aactgaaatc 300

 agtaggaatc tgtaccatca aaggtataca gatgacaaca agaagagctc 350

 tatgcaatgt caaaggactc tcagaagcca aagtagacaa gattaaagag 400

 gcagcgaaca aactaattga accaggattc ttgactgcat ttgagtatag 450

 tgaaaagagg aaaatggttt tccatatcac caccgggagc caggaatttg 500

 ataagttact aggaggtgga attgaaagta tggcaattac agaagctttt 550

 ggagaatttc gtactggaaa aacccagctt tctcataccc tctgtgtgac 600

 agctcaactt ccaggagctg gtggctaccc aggaggaaag attatcttca 650

 ttgatacaga aaatactttc cgtccagatc gccttaggga cattgctgat 700

 cgctttaatg tagaccatga tgcagtactg gacaacgtac tttatgcacg 750

 tgcatatact agtgaacatc agatggagct acttgattat gtagcagcaa 800

 agttccatga agaagctggc atcttcaagc tattgattat cgattcaata 850

 atggcacttt ttcgagtgga tttcagtggc cgtggggagt tggccgaacg 900

 gcagcaaaaa ttggcccaga tgttgtcacg actccaaaaa atctcagaag 950

 aatataacgt ggctgttttt gtgaccaatc aaatgactgc cgatccagga 1000

 gcaactatga cctttcaggc agatcccaaa aaacccattg ggggacacat 1050

 tctggctcat gcttcaacaa caagaataag cttgcgaaag ggaagaggag 1100

 agctcagaat tgccaagatt tatgacagtc ctgagatgcc tgaaaatgaa 1150

 gccaccttcg caataactgc tggaggaatt ggggatgcca aggagtaggt 1200

 ggtgaattga tgcaaattgc ttcttagtgc ttattaggag ctgaagaaat 1250

 ggaaaagcag tctccaattt cacatcttga aatagaggtt ttttcccaca 1300

 tgttactaaa gaaaagtcag caaagagatt taaatcttat atttatctta 1350

 aaagtccctg atttatgata actatacatt gtatgtaaat tcagggatat 1400

 gtatatgtat gtttgtgtgt gtgtgtgttt gtgtgtgtat acctgacata 1450

 tatagtagat atatatacct attgaaattc tctcactctg tgtatgtata 1500

 tatacctatg gaaaactagt tgttgggaaa ggagtacgtg attccctccc 1550

 tttcactttt caaagtgagc cactaaacag aaagtctaag agttcagaaa 1600

 tgtcccattc tcctaaggac tttcccttca ccatttttct agggtatagt 1650

 gccactgact tacatagcta gatgtttttc cacaagagga tttaagggag 1700

 gaatgtttat aggacacaca cacaaaagct ctttctattt ataatatcaa 1750

 actgcatatt cacctttata gcaacagaaa acagacatta aattaagcca 1800

 aattttaaat catttgactt tgacaagcag aaattacttt taaaaaatgt 1850

 atttatggct gggcgtggtg gctcacacct gtaatcccag cactttggga 1900

 ggccgaggca ggtggatcac ttgaggtcag gagttcaaga ccagcctggc 1950

 caacatggag aaaccccatc tctactaaaa atacaaaaat tagccaagtg 2000

 cagtggcatg tgcttgtaat cccagctact ctggaggctg aggcaggaga 2050

 attgcttgaa cccaggaggc agagattgcg gtgagccaag atggcaccac 2100

 tgcactccag cctaggtgac agagtgagac tccgtctcaa aaaaaaaaaa 2150

 aaaacttttt taaaatgtta aaattaattt aaatgtaaaa tttctgaata 2200

 ctaatcttag aaatgtgtaa aagatattat tttgattgtt aaacaaataa 2250

 aatcctgttt tcaaaatgc 2269

<210> 1756
<211> 340
<212> PRT
<213> Homo sapien

<400> 1756
 Met Lys Glu Asp Gln Val Val Ala Glu Glu Pro Gly Phe Gln Asp
   1               5                  10                  15

 Glu Glu Glu Ser Leu Phe Gln Asp Ile Asp Leu Leu Gln Lys His
                  20                  25                  30

 Gly Ile Asn Val Ala Asp Ile Lys Lys Leu Lys Ser Val Gly Ile
                  35                  40                  45

 Cys Thr Ile Lys Gly Ile Gln Met Thr Thr Arg Arg Ala Leu Cys
                  50                  55                  60

 Asn Val Lys Gly Leu Ser Glu Ala Lys Val Asp Lys Ile Lys Glu
                  65                  70                  75

 Ala Ala Asn Lys Leu Ile Glu Pro Gly Phe Leu Thr Ala Phe Glu
                  80                  85                  90

 Tyr Ser Glu Lys Arg Lys Met Val Phe His Ile Thr Thr Gly Ser
                  95                 100                 105

 Gln Glu Phe Asp Lys Leu Leu Gly Gly Gly Ile Glu Ser Met Ala
                 110                 115                 120

 Ile Thr Glu Ala Phe Gly Glu Phe Arg Thr Gly Lys Thr Gln Leu
                 125                 130                 135

 Ser His Thr Leu Cys Val Thr Ala Gln Leu Pro Gly Ala Gly Gly
                 140                 145                 150

 Tyr Pro Gly Gly Lys Ile Ile Phe Ile Asp Thr Glu Asn Thr Phe
                 155                 160                 165

 Arg Pro Asp Arg Leu Arg Asp Ile Ala Asp Arg Phe Asn Val Asp
                 170                 175                 180

 His Asp Ala Val Leu Asp Asn Val Leu Tyr Ala Arg Ala Tyr Thr
                 185                 190                 195

 Ser Glu His Gln Met Glu Leu Leu Asp Tyr Val Ala Ala Lys Phe
                 200                 205                 210

 His Glu Glu Ala Gly Ile Phe Lys Leu Leu Ile Ile Asp Ser Ile
                 215                 220                 225

 Met Ala Leu Phe Arg Val Asp Phe Ser Gly Arg Gly Glu Leu Ala
                 230                 235                 240

 Glu Arg Gln Gln Lys Leu Ala Gln Met Leu Ser Arg Leu Gln Lys
                 245                 250                 255

 Ile Ser Glu Glu Tyr Asn Val Ala Val Phe Val Thr Asn Gln Met
                 260                 265                 270

 Thr Ala Asp Pro Gly Ala Thr Met Thr Phe Gln Ala Asp Pro Lys
                 275                 280                 285

 Lys Pro Ile Gly Gly His Ile Leu Ala His Ala Ser Thr Thr Arg
                 290                 295                 300

 Ile Ser Leu Arg Lys Gly Arg Gly Glu Leu Arg Ile Ala Lys Ile
                 305                 310                 315

 Tyr Asp Ser Pro Glu Met Pro Glu Asn Glu Ala Thr Phe Ala Ile
                 320                 325                 330

 Thr Ala Gly Gly Ile Gly Asp Ala Lys Glu
                 335                 340

<210> 1757
<211> 2431
<212> DNA
<213> Homo sapien

<400> 1757
 gttttgcctg ctagcatctc cctgtaactc tcccaatctt gaggagtgat 50

 ccctgtccca gcccctggaa aggggcagga acgacaaact caaagtccag 100

 gatgttcacc atgacaagag ccatggaaga ggctcttttt cagcacttca 150

 tgcaccagaa gctggggatc gcctatgcca tacacaagcc atttcccttc 200

 tttgaaggcc tcctagacaa ctccatcatc actaagagaa tgtacatgga 250

 atctctggaa gcctgtagaa atttgatccc tgtatccaga gtggtgcaca 300

 acattctcac ccaactggag aggactttta acctgtctct tctggtgaca 350

 ttgttcagtc aaattaacct gcgtgaatat cccaatctgg tgacgattta 400

 cagaagcttc aaacgtgttg gtgcttccta tgaacggcag agcagagaca 450

 caccaatcct acttgaagcc ccaactggcc tagcagaagg aagctccctc 500

 cataccccac tggcgctgcc cccaccacaa ccccctcaac caagctgttc 550

 accctgtgcg ccaagagtca gtgagcctgg aacatcctcc cagcaaagcg 600

 atgagatcct gagtgagtcg cccagcccat ctgaccctgt cctgcctctc 650

 cctgcactca tccaggaagg aagaagcact tcagtgacca atgacaagtt 700

 aacatccaaa atgaatgcgg aagaagactc agaagagatg cccagcctcc 750

 tcactagcac tgtgcaagtg gccagtgaca acctgatccc ccaaataaga 800

 gataaagaag accctcaaga gatgccccac tctcccttgg gctctatgcc 850

 agagataaga gataattctc cagaaccaaa tgacccagaa gagccccagg 900

 aggtgtccag cacaccttca gacaagaaag gaaagaaaag aaaaagatgt 950

 atctggtcaa ctccaaaaag gagacataag aaaaaaagcc tcccaagagg 1000

 gacagcctca tctagacacg gaatccaaaa gaagctcaaa agggtggatc 1050

 aggttcctca aaagaaagat gactcaactt gtaactccac ggtagagaca 1100

 agggcccaaa aggcgagaac tgaatgtgcc cgaaagtcga gatcagagga 1150

 gatcattgat ggcacttcag aaatgaatga aggaaagagg tcccagaaga 1200

 cgcctagtac accacgaagg gtcacacaag gggcagcctc acctgggcat 1250

 ggcatccaag agaagctcca agtggtggat aaggtgactc aaaggaaaga 1300

 cgactcaacc tggaactcag aggtcatgat gagggtccaa aaggcaagaa 1350

 ctaaatgtgc ccgaaagtcc agatcgaaag aaaagaaaaa ggagaaagat 1400

 atctgttcaa gctcaaaaag gagatttcag aaaaatattc accgaagagg 1450

 aaaacccaaa agtgacactg tggattttca ctgttctaag ctccccgtga 1500

 cctgtggtga ggcgaaaggg attttatata agaagaaaat gaaacacgga 1550

 tcctcagtga agtgcattcg gaatgaggat ggaacttggt taacaccaaa 1600

 tgaatttgaa gtcgaaggaa aaggaaggaa cgcaaagaac tggaaacgga 1650

 atatacgttg tgaaggaatg accctaggag agctgctgaa gcggaaaaac 1700

 tcggatgaat gcgaggtgtg ctgtcaaggg ggacaacttc tctgctgcgg 1750

 tacttgtcca cgagtcttcc atgaggactg tcacatcccc cctgtggaag 1800

 ccaagaggat gctgtggagt tgcaccttct gcaggatgaa gaggtcttca 1850

 ggaagccaac agtgccatca tgtatctaag accctggaga ggcagatgca 1900

 gcctcaggac cagctgaaat gtgagttcct cctcttgaag gcctactgtc 1950

 atccacaaag ctcctttttt acgggcatcc catttaatat tcgagattac 2000

 ggtgagccct ttcaggaagc aatgtggttg gacctggtta aggaaaggct 2050

 gattacggaa atgtacacgg tggcatggtt tgtgcgagac atgcgcctga 2100

 tgtttcgcaa ccataaaaca ttttacaagg cttctgactt tggccaggta 2150

 ggacttgact tagaggcaga atttgaaaaa gatctcaaag acgtgctcgg 2200

 ttttcatgaa gccaatgacg gcggtttctg gactcttcct tgaccctgtt 2250

 ctgtaaagac tgaagcatcc ccacctcagg attcagctga tgggaccctg 2300

 gcttggactg ttgattgcca gtgagtctgg gatgtaattg gctgccctca 2350

 ggacccaaac ccagacactt cataggatta tcacaccctc catctttatt 2400

 ctttcttttt acctttaaaa gtctatatct a 2431

<210> 1758
<211> 713
<212> PRT
<213> Homo sapien

<400> 1758
 Met Phe Thr Met Thr Arg Ala Met Glu Glu Ala Leu Phe Gln His
   1               5                  10                  15

 Phe Met His Gln Lys Leu Gly Ile Ala Tyr Ala Ile His Lys Pro
                  20                  25                  30

 Phe Pro Phe Phe Glu Gly Leu Leu Asp Asn Ser Ile Ile Thr Lys
                  35                  40                  45

 Arg Met Tyr Met Glu Ser Leu Glu Ala Cys Arg Asn Leu Ile Pro
                  50                  55                  60

 Val Ser Arg Val Val His Asn Ile Leu Thr Gln Leu Glu Arg Thr
                  65                  70                  75

 Phe Asn Leu Ser Leu Leu Val Thr Leu Phe Ser Gln Ile Asn Leu
                  80                  85                  90

 Arg Glu Tyr Pro Asn Leu Val Thr Ile Tyr Arg Ser Phe Lys Arg
                  95                 100                 105

 Val Gly Ala Ser Tyr Glu Arg Gln Ser Arg Asp Thr Pro Ile Leu
                 110                 115                 120

 Leu Glu Ala Pro Thr Gly Leu Ala Glu Gly Ser Ser Leu His Thr
                 125                 130                 135

 Pro Leu Ala Leu Pro Pro Pro Gln Pro Pro Gln Pro Ser Cys Ser
                 140                 145                 150

 Pro Cys Ala Pro Arg Val Ser Glu Pro Gly Thr Ser Ser Gln Gln
                 155                 160                 165

 Ser Asp Glu Ile Leu Ser Glu Ser Pro Ser Pro Ser Asp Pro Val
                 170                 175                 180

 Leu Pro Leu Pro Ala Leu Ile Gln Glu Gly Arg Ser Thr Ser Val
                 185                 190                 195

 Thr Asn Asp Lys Leu Thr Ser Lys Met Asn Ala Glu Glu Asp Ser
                 200                 205                 210

 Glu Glu Met Pro Ser Leu Leu Thr Ser Thr Val Gln Val Ala Ser
                 215                 220                 225

 Asp Asn Leu Ile Pro Gln Ile Arg Asp Lys Glu Asp Pro Gln Glu
                 230                 235                 240

 Met Pro His Ser Pro Leu Gly Ser Met Pro Glu Ile Arg Asp Asn
                 245                 250                 255

 Ser Pro Glu Pro Asn Asp Pro Glu Glu Pro Gln Glu Val Ser Ser
                 260                 265                 270

 Thr Pro Ser Asp Lys Lys Gly Lys Lys Arg Lys Arg Cys Ile Trp
                 275                 280                 285

 Ser Thr Pro Lys Arg Arg His Lys Lys Lys Ser Leu Pro Arg Gly
                 290                 295                 300

 Thr Ala Ser Ser Arg His Gly Ile Gln Lys Lys Leu Lys Arg Val
                 305                 310                 315

 Asp Gln Val Pro Gln Lys Lys Asp Asp Ser Thr Cys Asn Ser Thr
                 320                 325                 330

 Val Glu Thr Arg Ala Gln Lys Ala Arg Thr Glu Cys Ala Arg Lys
                 335                 340                 345

 Ser Arg Ser Glu Glu Ile Ile Asp Gly Thr Ser Glu Met Asn Glu
                 350                 355                 360

 Gly Lys Arg Ser Gln Lys Thr Pro Ser Thr Pro Arg Arg Val Thr
                 365                 370                 375

 Gln Gly Ala Ala Ser Pro Gly His Gly Ile Gln Glu Lys Leu Gln
                 380                 385                 390

 Val Val Asp Lys Val Thr Gln Arg Lys Asp Asp Ser Thr Trp Asn
                 395                 400                 405

 Ser Glu Val Met Met Arg Val Gln Lys Ala Arg Thr Lys Cys Ala
                 410                 415                 420

 Arg Lys Ser Arg Ser Lys Glu Lys Lys Lys Glu Lys Asp Ile Cys
                 425                 430                 435

 Ser Ser Ser Lys Arg Arg Phe Gln Lys Asn Ile His Arg Arg Gly
                 440                 445                 450

 Lys Pro Lys Ser Asp Thr Val Asp Phe His Cys Ser Lys Leu Pro
                 455                 460                 465

 Val Thr Cys Gly Glu Ala Lys Gly Ile Leu Tyr Lys Lys Lys Met
                 470                 475                 480

 Lys His Gly Ser Ser Val Lys Cys Ile Arg Asn Glu Asp Gly Thr
                 485                 490                 495

 Trp Leu Thr Pro Asn Glu Phe Glu Val Glu Gly Lys Gly Arg Asn
                 500                 505                 510

 Ala Lys Asn Trp Lys Arg Asn Ile Arg Cys Glu Gly Met Thr Leu
                 515                 520                 525

 Gly Glu Leu Leu Lys Arg Lys Asn Ser Asp Glu Cys Glu Val Cys
                 530                 535                 540

 Cys Gln Gly Gly Gln Leu Leu Cys Cys Gly Thr Cys Pro Arg Val
                 545                 550                 555

 Phe His Glu Asp Cys His Ile Pro Pro Val Glu Ala Lys Arg Met
                 560                 565                 570

 Leu Trp Ser Cys Thr Phe Cys Arg Met Lys Arg Ser Ser Gly Ser
                 575                 580                 585

 Gln Gln Cys His His Val Ser Lys Thr Leu Glu Arg Gln Met Gln
                 590                 595                 600

 Pro Gln Asp Gln Leu Lys Cys Glu Phe Leu Leu Leu Lys Ala Tyr
                 605                 610                 615

 Cys His Pro Gln Ser Ser Phe Phe Thr Gly Ile Pro Phe Asn Ile
                 620                 625                 630

 Arg Asp Tyr Gly Glu Pro Phe Gln Glu Ala Met Trp Leu Asp Leu
                 635                 640                 645

 Val Lys Glu Arg Leu Ile Thr Glu Met Tyr Thr Val Ala Trp Phe
                 650                 655                 660

 Val Arg Asp Met Arg Leu Met Phe Arg Asn His Lys Thr Phe Tyr
                 665                 670                 675

 Lys Ala Ser Asp Phe Gly Gln Val Gly Leu Asp Leu Glu Ala Glu
                 680                 685                 690

 Phe Glu Lys Asp Leu Lys Asp Val Leu Gly Phe His Glu Ala Asn
                 695                 700                 705

 Asp Gly Gly Phe Trp Thr Leu Pro
                 710

<210> 1759
<211> 5891
<212> DNA
<213> Homo sapien

<400> 1759
 ccaggagagc ggcgtggacg cgtgcgggcc tagaggccca cgtgatccgc 50

 agggcggccg aggcaggaag ctgtgagtgc gcggttgcgg ggtcgcattg 100

 tggctacggc tttgcgtccc cggcgggcag ccccaggctg gtccccgcct 150

 ccgctctccc caccggcggg gaaagcagct ggtgtgggag gaaaggctcc 200

 atcccccgcc ccctctctcc cgctgttggc tggcaggatc ttttggcagt 250

 cctgtggcct cgctccccgc ccggatcctc ctgaccctga gattcgcggg 300

 tctcacgtcc cgtgcacgcc ttgcttcggc ctcagttaag cctttgtgga 350

 ctccaggtcc ctggtgagat tagaaacgtt tgcaaacatg tcccggatcg 400

 aaaagatgag cattctgggc gtgcggagtt ttggaataga ggacaaagat 450

 aagcaaatta tcactttctt cagccccctt acaattttgg ttggacccaa 500

 tggggcggga aagacgacca tcattgaatg tctaaaatat atttgtactg 550

 gagatttccc tcctggaacc aaaggaaata catttgtaca cgatcccaag 600

 gttgctcaag aaacagatgt gagagcccag attcgtctgc aatttcgtga 650

 tgtcaatgga gaacttatag ctgtgcaaag atctatggtg tgtactcaga 700

 aaagcaaaaa gacagaattt aaaactctgg aaggagtcat tactagaaca 750

 aagcatggtg aaaaggtcag tctgagctct aagtgtgcag aaattgaccg 800

 agaaatgatc agttctcttg gggtttccaa ggctgtgcta aataatgtca 850

 ttttctgtca tcaagaagat tctaattggc ctttaagtga aggaaaggct 900

 ttgaagcaaa agtttgatga gattttttca gcaacaagat acattaaagc 950

 cttagaaaca cttcggcagg tacgtcagac acaaggtcag aaagtaaaag 1000

 aatatcaaat ggaactaaaa tatctgaagc aatataagga aaaagcttgt 1050

 gagattcgtg atcagattac aagtaaggaa gcccagttaa catcttcaaa 1100

 ggaaattgtc aaatcctatg agaatgaact tgatccattg aagaatcgtc 1150

 taaaagaaat tgaacataat ctctctaaaa taatgaaact tgacaatgaa 1200

 attaaagcct tggatagccg aaagaagcaa atggagaaag ataatagtga 1250

 actggaagag aaaatggaaa aggtttttca agggactgat gagcaactaa 1300

 atgacttata tcacaatcac cagagaacag taagggagaa agaaaggaaa 1350

 ttggtagact gtcatcgtga actggaaaaa ctaaataaag aatctaggct 1400

 tctcaatcag gaaaaatcag aactgcttgt tgaacagggt cgtctacagc 1450

 tgcaagcaga tcgccatcaa gaacatatcc gagctagaga ttcattaatt 1500

 cagtctttgg caacacagct agaattggat ggctttgagc gtggaccatt 1550

 cagtgaaaga cagattaaaa attttcacaa acttgtgaga gagagacaag 1600

 aaggggaagc aaaaactgcc aaccaactga tgaatgactt tgcagaaaaa 1650

 gagactctga aacaaaaaca gatagatgag ataagagata agaaaactgg 1700

 actgggaaga ataattgagt taaaatcaga aatcctaagt aagaagcaga 1750

 atgagctgaa aaatgtgaag tatgaattac agcagttgga aggatcttca 1800

 gacaggattc ttgaactgga ccaggagctc ataaaagctg aacgtgagtt 1850

 aagcaaggct gagaaaaaca gcaatgtaga aaccttaaaa atggaagtaa 1900

 taagtctcca aaatgaaaaa gcagacttag acaggaccct gcgtaaactt 1950

 gaccaggaga tggagcagtt aaaccatcat acaacaacac gtacccaaat 2000

 ggagatgctg accaaagaca aagctgacaa agatgaacaa atcagaaaaa 2050

 taaaatctag gcacagtgat gaattaacct cactgttggg atattttccc 2100

 aacaaaaaac agcttgaaga ctggctacat agtaaatcaa aagaaattaa 2150

 tcagaccagg gacagacttg ccaaattgaa caaggaacta gcttcatctg 2200

 agcagaataa aaatcatata aataatgaac taaaaagaaa ggaagagcag 2250

 ttgtccagtt acgaagacaa gctgtttgat gtttgtggta gccaggattt 2300

 tgaaagtgat ttagacaggc ttaaagagga aattgaaaaa tcatcaaaac 2350

 agcgagccat gctggctgga gccacagcag tttactccca gttcattact 2400

 cagctaacag acgaaaacca gtcatgttgc cccgtttgtc agagagtttt 2450

 tcagacagag gctgagttac aagaagtcat cagtgatttg cagtctaaac 2500

 tgcgacttgc tccagataaa ctcaagtcaa cagaatcaga gctaaaaaaa 2550

 aaggaaaagc ggcgtgatga aatgctggga cttgtgccca tgaggcaaag 2600

 cataattgat ttgaaggaga aggaaatacc agaattaaga aacaaactgc 2650

 agaatgtcaa tagagacata cagcgcctaa agaacgacat agaagaacaa 2700

 gaaacactct tgggtacaat aatgcctgaa gaagaaagtg ccaaagtatg 2750

 cctgacagat gttacaatta tggagaggtt ccagatggaa cttaaagatg 2800

 ttgaaagaaa aattgcacaa caagcagcta agctacaagg aatagactta 2850

 gatcgaactg tccaacaagt caaccaggag aaacaagaga aacagcacaa 2900

 gttagacaca gtttctagta agattgaatt gaatcgtaag cttatacagg 2950

 accagcagga acagattcaa catctaaaaa gtacaacaaa tgagctaaaa 3000

 tctgagaaac ttcagatatc cactaatttg caacgtcgtc agcaactgga 3050

 ggagcagact gtggaattat ccactgaagt tcagtctttg tacagagaga 3100

 taaaggatgc taaagagcag gtaagccctt tggaaacaac attggaaaag 3150

 ttccagcaag aaaaagaaga attaatcaac aaaaaaaata caagcaacaa 3200

 aatagcacag gataaactga atgatattaa agagaaggtt aaaaatattc 3250

 atggctatat gaaagacatt gagaattata ttcaagatgg gaaagacgac 3300

 tataagaagc aaaaagaaac tgaacttaat aaagtaatag ctcaactaag 3350

 tgaatgcgag aaacacaaag aaaagataaa tgaagatatg agactcatga 3400

 gacaagatat tgatacacag aagatacaag aaaggtggct acaagataac 3450

 cttactttaa gaaaaagaaa tgaggaacta aaagaagttg aagaagaaag 3500

 aaaacaacat ttgaaggaaa tgggtcaaat gcaggttttg caaatgaaaa 3550

 gtgaacatca gaagttggaa gagaacatag acaatataaa aagaaatcat 3600

 aatttggcat tagggcgaca gaaaggttat gaagaagaaa ttattcattt 3650

 taagaaagaa cttcgagaac cacaatttcg ggatgctgag gaaaagtata 3700

 gagaaatgat gattgttatg aggacaacag aacttgtgaa caaggatctg 3750

 gatatttatt ataagactct tgaccaagca ataatgaaat ttcacagtat 3800

 gaaaatggaa gaaatcaata aaattatacg tgacctgtgg cgaagtacct 3850

 atcgtggaca agatattgaa tacatagaaa tacggtctga tgccgatgaa 3900

 aatgtatcag cttctgataa aaggcggaat tataactacc gagtggtgat 3950

 gctgaaggga gacacagcct tggatatgcg aggacgatgc agtgctggac 4000

 aaaaggtatt agcctcactc atcattcgcc tggccctggc tgaaacgttc 4050

 tgcctcaact gtggcatcat tgccttggat gagccaacaa caaatcttga 4100

 ccgagaaaac attgaatctc ttgcacatgc tctggttgag ataataaaaa 4150

 gtcgctcaca gcagcgtaac ttccagcttc tggtaatcac tcatgatgaa 4200

 gattttgtgg agcttttagg acgttctgaa tatgtggaga aattctacag 4250

 gattaaaaag aacatcgatc agtgctcaga gattgtgaaa tgcagtgtta 4300

 gctccctggg attcaatgtt cattaaaaat atccaagatt taaatgccat 4350

 agaaatgtag gtcctcagaa agtgtataat aagaaactta tttctcatat 4400

 caacttagtc aataagaaaa tatattcttt caaaggaaca ttgtgtctag 4450

 gattttggat gttgagaggt tctaaaatca tgaaacttgt ttcactgaaa 4500

 attggacaga ttgcctgttt ctgatttgct gctcttcatc ccattccagg 4550

 cagcctctgt caggccttca gggttcagca gtacagccga gactcgactc 4600

 tgtgcctccc tccccagtgc aaatgcatgc ttcttctcaa agcactgttg 4650

 agaaggagat aattactgcc ttgaaaattt atggttttgg tattttttta 4700

 aatcatagtt aaatgttacc tctgaattta cttccttgca tgtggtttga 4750

 aaaactgagt attaatatct gaggatgacc agaaatggtg agatgtatgt 4800

 ttggctctgc ttttaacttt ataaatccag tgacctctct ctctgggact 4850

 tggtttcccc aactaaaatt tgaagtagtt gaatggggtc tcaaagtttg 4900

 acaggaacct taagtaatca tctaagtcag tacccaccac cttcttctcc 4950

 tacatatccc ttccagatgg tcatccagac tcagagctct ctctacagag 5000

 aggaaattct ccactgtgca cacccacctt tggaaagctc tgaccacttg 5050

 aggcctgatc tgcccatcgt gaagaagcct gtaacactcc tctgcgtcta 5100

 tcctgtgtag catactggct tcaccatcaa tcctgattcc tctctaagtg 5150

 ggcattgcca tgtggaaggc aagccaggct cactcacaga gtcaaggcct 5200

 gctccctgta gggtccaacc agacctggaa gaacaggcct ctccatttgc 5250

 tcttcagatg ccacttctaa gaaaagccta atcacagttt ttcctggaat 5300

 tgccagctga catcttgaat ccttccattc cacacagaat gcaaccaagt 5350

 cacacgcttt tgaattatgc tttgtagagt tttgtcattc agagtcagcc 5400

 aggaccatac cgggtcttga ttcagtcaca tggcatggtt ttgtgccatc 5450

 tgtagctata atgagcatgt ttgcctagac agcttttctc aactgggtcc 5500

 agaagagaat taagccctaa ggtcctaagg catctatctg tgctaggtta 5550

 aatggttggc ccccaaagat agacaggtcc tgatttctag aacccgtgac 5600

 tgttacttta tacagcaaag gaaactttgc agatgtgatt aaagctaagg 5650

 accttaagac agagtatcct gggggtggtg gtggggtggg ggggggtcct 5700

 aaatgtaatc acgagtaaga ttaagagcaa atcaattcta gtcatatatt 5750

 aaacatccac aataaccaag atatttttat cccaagaatg caagatttca 5800

 gaaaatgaaa aatctgttga taaatccatc actataataa aaccgaaggt 5850

 gaaaaaaatt ctgaaaaaaa aaaaaaaaaa aaaaaaaaaa a 5891

<210> 1760
<211> 1312
<212> PRT
<213> Homo sapien

<400> 1760
 Met Ser Arg Ile Glu Lys Met Ser Ile Leu Gly Val Arg Ser Phe
   1               5                  10                  15

 Gly Ile Glu Asp Lys Asp Lys Gln Ile Ile Thr Phe Phe Ser Pro
                  20                  25                  30

 Leu Thr Ile Leu Val Gly Pro Asn Gly Ala Gly Lys Thr Thr Ile
                  35                  40                  45

 Ile Glu Cys Leu Lys Tyr Ile Cys Thr Gly Asp Phe Pro Pro Gly
                  50                  55                  60

 Thr Lys Gly Asn Thr Phe Val His Asp Pro Lys Val Ala Gln Glu
                  65                  70                  75

 Thr Asp Val Arg Ala Gln Ile Arg Leu Gln Phe Arg Asp Val Asn
                  80                  85                  90

 Gly Glu Leu Ile Ala Val Gln Arg Ser Met Val Cys Thr Gln Lys
                  95                 100                 105

 Ser Lys Lys Thr Glu Phe Lys Thr Leu Glu Gly Val Ile Thr Arg
                 110                 115                 120

 Thr Lys His Gly Glu Lys Val Ser Leu Ser Ser Lys Cys Ala Glu
                 125                 130                 135

 Ile Asp Arg Glu Met Ile Ser Ser Leu Gly Val Ser Lys Ala Val
                 140                 145                 150

 Leu Asn Asn Val Ile Phe Cys His Gln Glu Asp Ser Asn Trp Pro
                 155                 160                 165

 Leu Ser Glu Gly Lys Ala Leu Lys Gln Lys Phe Asp Glu Ile Phe
                 170                 175                 180

 Ser Ala Thr Arg Tyr Ile Lys Ala Leu Glu Thr Leu Arg Gln Val
                 185                 190                 195

 Arg Gln Thr Gln Gly Gln Lys Val Lys Glu Tyr Gln Met Glu Leu
                 200                 205                 210

 Lys Tyr Leu Lys Gln Tyr Lys Glu Lys Ala Cys Glu Ile Arg Asp
                 215                 220                 225

 Gln Ile Thr Ser Lys Glu Ala Gln Leu Thr Ser Ser Lys Glu Ile
                 230                 235                 240

 Val Lys Ser Tyr Glu Asn Glu Leu Asp Pro Leu Lys Asn Arg Leu
                 245                 250                 255

 Lys Glu Ile Glu His Asn Leu Ser Lys Ile Met Lys Leu Asp Asn
                 260                 265                 270

 Glu Ile Lys Ala Leu Asp Ser Arg Lys Lys Gln Met Glu Lys Asp
                 275                 280                 285

 Asn Ser Glu Leu Glu Glu Lys Met Glu Lys Val Phe Gln Gly Thr
                 290                 295                 300

 Asp Glu Gln Leu Asn Asp Leu Tyr His Asn His Gln Arg Thr Val
                 305                 310                 315

 Arg Glu Lys Glu Arg Lys Leu Val Asp Cys His Arg Glu Leu Glu
                 320                 325                 330

 Lys Leu Asn Lys Glu Ser Arg Leu Leu Asn Gln Glu Lys Ser Glu
                 335                 340                 345

 Leu Leu Val Glu Gln Gly Arg Leu Gln Leu Gln Ala Asp Arg His
                 350                 355                 360

 Gln Glu His Ile Arg Ala Arg Asp Ser Leu Ile Gln Ser Leu Ala
                 365                 370                 375

 Thr Gln Leu Glu Leu Asp Gly Phe Glu Arg Gly Pro Phe Ser Glu
                 380                 385                 390

 Arg Gln Ile Lys Asn Phe His Lys Leu Val Arg Glu Arg Gln Glu
                 395                 400                 405

 Gly Glu Ala Lys Thr Ala Asn Gln Leu Met Asn Asp Phe Ala Glu
                 410                 415                 420

 Lys Glu Thr Leu Lys Gln Lys Gln Ile Asp Glu Ile Arg Asp Lys
                 425                 430                 435

 Lys Thr Gly Leu Gly Arg Ile Ile Glu Leu Lys Ser Glu Ile Leu
                 440                 445                 450

 Ser Lys Lys Gln Asn Glu Leu Lys Asn Val Lys Tyr Glu Leu Gln
                 455                 460                 465

 Gln Leu Glu Gly Ser Ser Asp Arg Ile Leu Glu Leu Asp Gln Glu
                 470                 475                 480

 Leu Ile Lys Ala Glu Arg Glu Leu Ser Lys Ala Glu Lys Asn Ser
                 485                 490                 495

 Asn Val Glu Thr Leu Lys Met Glu Val Ile Ser Leu Gln Asn Glu
                 500                 505                 510

 Lys Ala Asp Leu Asp Arg Thr Leu Arg Lys Leu Asp Gln Glu Met
                 515                 520                 525

 Glu Gln Leu Asn His His Thr Thr Thr Arg Thr Gln Met Glu Met
                 530                 535                 540

 Leu Thr Lys Asp Lys Ala Asp Lys Asp Glu Gln Ile Arg Lys Ile
                 545                 550                 555

 Lys Ser Arg His Ser Asp Glu Leu Thr Ser Leu Leu Gly Tyr Phe
                 560                 565                 570

 Pro Asn Lys Lys Gln Leu Glu Asp Trp Leu His Ser Lys Ser Lys
                 575                 580                 585

 Glu Ile Asn Gln Thr Arg Asp Arg Leu Ala Lys Leu Asn Lys Glu
                 590                 595                 600

 Leu Ala Ser Ser Glu Gln Asn Lys Asn His Ile Asn Asn Glu Leu
                 605                 610                 615

 Lys Arg Lys Glu Glu Gln Leu Ser Ser Tyr Glu Asp Lys Leu Phe
                 620                 625                 630

 Asp Val Cys Gly Ser Gln Asp Phe Glu Ser Asp Leu Asp Arg Leu
                 635                 640                 645

 Lys Glu Glu Ile Glu Lys Ser Ser Lys Gln Arg Ala Met Leu Ala
                 650                 655                 660

 Gly Ala Thr Ala Val Tyr Ser Gln Phe Ile Thr Gln Leu Thr Asp
                 665                 670                 675

 Glu Asn Gln Ser Cys Cys Pro Val Cys Gln Arg Val Phe Gln Thr
                 680                 685                 690

 Glu Ala Glu Leu Gln Glu Val Ile Ser Asp Leu Gln Ser Lys Leu
                 695                 700                 705

 Arg Leu Ala Pro Asp Lys Leu Lys Ser Thr Glu Ser Glu Leu Lys
                 710                 715                 720

 Lys Lys Glu Lys Arg Arg Asp Glu Met Leu Gly Leu Val Pro Met
                 725                 730                 735

 Arg Gln Ser Ile Ile Asp Leu Lys Glu Lys Glu Ile Pro Glu Leu
                 740                 745                 750

 Arg Asn Lys Leu Gln Asn Val Asn Arg Asp Ile Gln Arg Leu Lys
                 755                 760                 765

 Asn Asp Ile Glu Glu Gln Glu Thr Leu Leu Gly Thr Ile Met Pro
                 770                 775                 780

 Glu Glu Glu Ser Ala Lys Val Cys Leu Thr Asp Val Thr Ile Met
                 785                 790                 795

 Glu Arg Phe Gln Met Glu Leu Lys Asp Val Glu Arg Lys Ile Ala
                 800                 805                 810

 Gln Gln Ala Ala Lys Leu Gln Gly Ile Asp Leu Asp Arg Thr Val
                 815                 820                 825

 Gln Gln Val Asn Gln Glu Lys Gln Glu Lys Gln His Lys Leu Asp
                 830                 835                 840

 Thr Val Ser Ser Lys Ile Glu Leu Asn Arg Lys Leu Ile Gln Asp
                 845                 850                 855

 Gln Gln Glu Gln Ile Gln His Leu Lys Ser Thr Thr Asn Glu Leu
                 860                 865                 870

 Lys Ser Glu Lys Leu Gln Ile Ser Thr Asn Leu Gln Arg Arg Gln
                 875                 880                 885

 Gln Leu Glu Glu Gln Thr Val Glu Leu Ser Thr Glu Val Gln Ser
                 890                 895                 900

 Leu Tyr Arg Glu Ile Lys Asp Ala Lys Glu Gln Val Ser Pro Leu
                 905                 910                 915

 Glu Thr Thr Leu Glu Lys Phe Gln Gln Glu Lys Glu Glu Leu Ile
                 920                 925                 930

 Asn Lys Lys Asn Thr Ser Asn Lys Ile Ala Gln Asp Lys Leu Asn
                 935                 940                 945

 Asp Ile Lys Glu Lys Val Lys Asn Ile His Gly Tyr Met Lys Asp
                 950                 955                 960

 Ile Glu Asn Tyr Ile Gln Asp Gly Lys Asp Asp Tyr Lys Lys Gln
                 965                 970                 975

 Lys Glu Thr Glu Leu Asn Lys Val Ile Ala Gln Leu Ser Glu Cys
                 980                 985                 990

 Glu Lys His Lys Glu Lys Ile Asn Glu Asp Met Arg Leu Met Arg
                 995                1000                1005

 Gln Asp Ile Asp Thr Gln Lys Ile Gln Glu Arg Trp Leu Gln Asp
                1010                1015                1020

 Asn Leu Thr Leu Arg Lys Arg Asn Glu Glu Leu Lys Glu Val Glu
                1025                1030                1035

 Glu Glu Arg Lys Gln His Leu Lys Glu Met Gly Gln Met Gln Val
                1040                1045                1050

 Leu Gln Met Lys Ser Glu His Gln Lys Leu Glu Glu Asn Ile Asp
                1055                1060                1065

 Asn Ile Lys Arg Asn His Asn Leu Ala Leu Gly Arg Gln Lys Gly
                1070                1075                1080

 Tyr Glu Glu Glu Ile Ile His Phe Lys Lys Glu Leu Arg Glu Pro
                1085                1090                1095

 Gln Phe Arg Asp Ala Glu Glu Lys Tyr Arg Glu Met Met Ile Val
                1100                1105                1110

 Met Arg Thr Thr Glu Leu Val Asn Lys Asp Leu Asp Ile Tyr Tyr
                1115                1120                1125

 Lys Thr Leu Asp Gln Ala Ile Met Lys Phe His Ser Met Lys Met
                1130                1135                1140

 Glu Glu Ile Asn Lys Ile Ile Arg Asp Leu Trp Arg Ser Thr Tyr
                1145                1150                1155

 Arg Gly Gln Asp Ile Glu Tyr Ile Glu Ile Arg Ser Asp Ala Asp
                1160                1165                1170

 Glu Asn Val Ser Ala Ser Asp Lys Arg Arg Asn Tyr Asn Tyr Arg
                1175                1180                1185

 Val Val Met Leu Lys Gly Asp Thr Ala Leu Asp Met Arg Gly Arg
                1190                1195                1200

 Cys Ser Ala Gly Gln Lys Val Leu Ala Ser Leu Ile Ile Arg Leu
                1205                1210                1215

 Ala Leu Ala Glu Thr Phe Cys Leu Asn Cys Gly Ile Ile Ala Leu
                1220                1225                1230

 Asp Glu Pro Thr Thr Asn Leu Asp Arg Glu Asn Ile Glu Ser Leu
                1235                1240                1245

 Ala His Ala Leu Val Glu Ile Ile Lys Ser Arg Ser Gln Gln Arg
                1250                1255                1260

 Asn Phe Gln Leu Leu Val Ile Thr His Asp Glu Asp Phe Val Glu
                1265                1270                1275

 Leu Leu Gly Arg Ser Glu Tyr Val Glu Lys Phe Tyr Arg Ile Lys
                1280                1285                1290

 Lys Asn Ile Asp Gln Cys Ser Glu Ile Val Lys Cys Ser Val Ser
                1295                1300                1305

 Ser Leu Gly Phe Asn Val His
                1310

<210> 1761
<211> 1552
<212> DNA
<213> Homo sapien

<400> 1761
 acagactgca gggctgacta gggttagttt ggaggaggga gtaagaggtg 50

 gggaggagga ggcacagtta atggatctgt aaacttgcac cctctttcag 100

 agtggtacat ggaagacagc acaaagtgga tccatactct gaaatgcagt 150

 aactctgatg cttgaatttg tctcccttct tgccagaaag gattctaata 200

 actcggtgtc aaagccaaga cataaactca accccttctc ttccaaaagc 250

 ttcacgttac agcatggaag ctgttgccaa gtttgatttc actgcttcag 300

 gtgaggatga actgagcttt cacactggag atgttttgaa gattttaagt 350

 aaccaagagg agtggtttaa ggcggagctt gggagccagg aaggatatgt 400

 gcccaagaat ttcatagaca tccagtttcc caaatggttt cacgaaggcc 450

 tctctcgaca ccaggcagag aacttactca tgggcaagga ggttggcttc 500

 ttcatcatcc gggccagcca gagctcccca ggggacttct ccatctctgt 550

 caggcatgag gatgacgttc aacacttcaa ggtcatgcga gacaacaagg 600

 gtaattactt tctgtggact gagaagtttc catccctaaa taagctggta 650

 gactactaca ggacaaattc catctccaga cagaagcaga tcttccttag 700

 agacagaacc cgagaagacc agggtcaccg gggcaacagc ctggaccgga 750

 ggtcccaggg aggcccacac ctcagtgggg ctgtgggaga agaaatccga 800

 ccttcgatga accggaagct gtcggatcac cccccgaccc ttcccctgca 850

 gcagcaccag caccagccac agcctccgca atatgcccca gcgccccagc 900

 agctgcagca gcccccacag cagcgatatc tgcagcacca ccatttccac 950

 caggaacgcc gaggaggcag ccttgacata aatgatgggc attgtggcac 1000

 cggcttgggc agtgaaatga atgcggccct catgcatcgg agacacacag 1050

 acccagtgca gctccaggcg gcagggcgag tgcggtgggc ccgggcgctg 1100

 tatgactttg aggccctgga ggatgacgag ctggggttcc acagcgggga 1150

 ggtggtggag gtcctggata gctccaaccc atcctggtgg accggccgcc 1200

 tgcacaacaa gctgggcctc ttccctgcca actacgtggc acccatgacc 1250

 cgataaactc ttcaggggac agaagctttt tgtctggagc tgcccacaag 1300

 aaagagggca aggaaaaaag gctggactcc atgactatat atacatacat 1350

 ctatctacat ctgcctgtgt acacacacaa ctttttatac tagtaattta 1400

 ttggcaattg ggctggtaat tagttgatgc aaaagggaac tcaggtggag 1450

 aataatattg acacttgctt ttctgccccc ctcaggggtg tgtggaaggc 1500

 agtgggggag ttgggagggg ggcagggaaa tgaaatggag ttttgtcctg 1550

 gc 1552

<210> 1762
<211> 330
<212> PRT
<213> Homo sapien

<400> 1762
 Met Glu Ala Val Ala Lys Phe Asp Phe Thr Ala Ser Gly Glu Asp
   1               5                  10                  15

 Glu Leu Ser Phe His Thr Gly Asp Val Leu Lys Ile Leu Ser Asn
                  20                  25                  30

 Gln Glu Glu Trp Phe Lys Ala Glu Leu Gly Ser Gln Glu Gly Tyr
                  35                  40                  45

 Val Pro Lys Asn Phe Ile Asp Ile Gln Phe Pro Lys Trp Phe His
                  50                  55                  60

 Glu Gly Leu Ser Arg His Gln Ala Glu Asn Leu Leu Met Gly Lys
                  65                  70                  75

 Glu Val Gly Phe Phe Ile Ile Arg Ala Ser Gln Ser Ser Pro Gly
                  80                  85                  90

 Asp Phe Ser Ile Ser Val Arg His Glu Asp Asp Val Gln His Phe
                  95                 100                 105

 Lys Val Met Arg Asp Asn Lys Gly Asn Tyr Phe Leu Trp Thr Glu
                 110                 115                 120

 Lys Phe Pro Ser Leu Asn Lys Leu Val Asp Tyr Tyr Arg Thr Asn
                 125                 130                 135

 Ser Ile Ser Arg Gln Lys Gln Ile Phe Leu Arg Asp Arg Thr Arg
                 140                 145                 150

 Glu Asp Gln Gly His Arg Gly Asn Ser Leu Asp Arg Arg Ser Gln
                 155                 160                 165

 Gly Gly Pro His Leu Ser Gly Ala Val Gly Glu Glu Ile Arg Pro
                 170                 175                 180

 Ser Met Asn Arg Lys Leu Ser Asp His Pro Pro Thr Leu Pro Leu
                 185                 190                 195

 Gln Gln His Gln His Gln Pro Gln Pro Pro Gln Tyr Ala Pro Ala
                 200                 205                 210

 Pro Gln Gln Leu Gln Gln Pro Pro Gln Gln Arg Tyr Leu Gln His
                 215                 220                 225

 His His Phe His Gln Glu Arg Arg Gly Gly Ser Leu Asp Ile Asn
                 230                 235                 240

 Asp Gly His Cys Gly Thr Gly Leu Gly Ser Glu Met Asn Ala Ala
                 245                 250                 255

 Leu Met His Arg Arg His Thr Asp Pro Val Gln Leu Gln Ala Ala
                 260                 265                 270

 Gly Arg Val Arg Trp Ala Arg Ala Leu Tyr Asp Phe Glu Ala Leu
                 275                 280                 285

 Glu Asp Asp Glu Leu Gly Phe His Ser Gly Glu Val Val Glu Val
                 290                 295                 300

 Leu Asp Ser Ser Asn Pro Ser Trp Trp Thr Gly Arg Leu His Asn
                 305                 310                 315

 Lys Leu Gly Leu Phe Pro Ala Asn Tyr Val Ala Pro Met Thr Arg
                 320                 325                 330

<210> 1763
<211> 4607
<212> DNA
<213> Homo sapien

<400> 1763
 gctggcggcg gccgcccagg gccggggccg cgcgcccagc ctgagcccgc 50

 cccgccgccg agcgtcaccg aacctgcttg aaatgcagcc gaggagccgg 100

 ggcgggcggc agcggcggcg gcggcggcgg cgggggcagc ggcaaccccg 150

 gcgccgcggc aaggactcgg agggctgaga cgcggcggcg gcggcgcggg 200

 gagcgcgggg cgcggcggcc ggagcccggg cccgccatgg gcctccccga 250

 gccgggccct ctccggcttc tggcgctgct gctgctgctg ctgctgctgc 300

 tgctgctgcg gctccagcat cttgcggcgg cagcggctga tccgctgctc 350

 ggcggccaag ggccggccaa ggagtgcgaa aaggaccaat tccagtgccg 400

 gaacgagcgc tgcatcccct ctgtgtggag atgcgacgag gacgatgact 450

 gcttagacca cagcgacgag gacgactgcc ccaagaagac ctgtgcagac 500

 agtgacttca cctgtgacaa cggccactgc atccacgaac ggtggaagtg 550

 tgacggcgag gaggagtgtc ctgatggctc cgatgagtcc gaggccactt 600

 gcaccaagca ggtgtgtcct gcagagaagc tgagctgtgg acccaccagc 650

 cacaagtgtg tacctgcctc gtggcgctgc gacggggaga aggactgcga 700

 gggtggagcg gatgaggccg gctgtgctac cttgtgcgcc ccgcacgagt 750

 tccagtgcgg caaccgctcg tgcctggccg ccgtgttcgt gtgcgacggc 800

 gatgacgact gtggtgacgg cagcgatgag cgcggctgtg cagacccggc 850

 ctgcgggccc cgcgagttcc gctgcggcgg cgatggcggc ggcgcctgca 900

 tcccggagcg ctgggtctgc gaccgccagt ttgactgcga ggaccgctcg 950

 gacgaggcag ccgagctctg cggccgcccg ggccccgggg ccacgtccgc 1000

 gcccgccgcc tgcgccaccg tctcccagtt cgcctgccgc agcggcgagt 1050

 gcgtgcacct gggctggcgc tgcgacggcg accgcgactg caaagacaaa 1100

 tcggacgagg ccgactgccc actgggcacc tgccgtgggg acgagttcca 1150

 gtgtggggat gggacatgtg tccttgcaat caagcactgc aaccaggagc 1200

 aggactgtcc agatgggagt gatgaagctg gctgcctaca ggggctgaac 1250

 gagtgtctgc acaacaatgg cggctgctca cacatctgca ctgacctcaa 1300

 gattggcttt gaatgcacgt gcccagcagg cttccagctc ctggaccaga 1350

 agacctgtgg cgacattgat gagtgcaagg acccagatgc ctgcagccag 1400

 atctgtgtca attacaaggg ctattttaag tgtgagtgct accctggcta 1450

 cgagatggac ctactgacca agaactgcaa ggctgctggt ggaaagagcc 1500

 catccctaat cttcaccaac cggtacgagg tgcggaggat cgacctggtg 1550

 aagcggaact attcacgcct catccccatg ctcaagaatg tcgtggcact 1600

 agatgtggaa gttgccacca atcgcatcta ctggtgtgac ctctcctacc 1650

 gtaagatcta tagcgcctac atggacaagg ccagtgaccc gaaagagcag 1700

 gaggtcctca ttgacgagca gttgcactct ccagagggcc tggcagtgga 1750

 ctgggtccac aagcacatct actggactga ctcgggcaat aagaccatct 1800

 cagtggccac agttgatggt ggccgccgac gcactctctt cagccgtaac 1850

 ctcagtgaac cccgggccat cgctgttgac cccctgcgag ggttcatgta 1900

 ttggtctgac tggggggacc aggccaagat tgagaaatct gggctcaacg 1950

 gtgtggaccg gcaaacactg gtgtcagaca atattgaatg gcccaacgga 2000

 atcaccctgg atctgctgag ccagcgcttg tactgggtag actccaagct 2050

 acaccaactg tccagcattg acttcagtgg aggcaacaga aagacgctga 2100

 tctcctccac tgacttcctg agccaccctt ttgggatagc tgtgtttgag 2150

 gacaaggtgt tctggacaga cctggagaac gaggccattt tcagtgcaaa 2200

 tcggctcaat ggcctggaaa tctccatcct ggctgagaac ctcaacaacc 2250

 cacatgacat tgtcatcttc catgagctga agcagccaag agctccagat 2300

 gcctgtgagc tgagtgtcca gcctaatgga ggctgtgaat acctgtgcct 2350

 tcctgctcct cagatctcca gccactctcc caagtacaca tgtgcctgtc 2400

 ctgacacaat gtggctgggt ccagacatga agaggtgcta ccgagcacct 2450

 caatctacct caactacgac gttagcttct accatgacga ggacagtacc 2500

 tgccaccaca agagcccccg ggaccaccgt ccacagatcc acctaccaga 2550

 accacagcac agagacacca agcctgacag ctgcagtccc aagctcagtt 2600

 agtgtcccca gggctcccag catcagcccg tctaccctaa gccctgcaac 2650

 cagcaaccac tcccagcact atgcaaatga agacagtaag atgggctcaa 2700

 cagtcactgc cgctgttatc gggatcatcg tgcccatagt ggtgatagcc 2750

 ctcctgtgca tgagtggata cctgatctgg agaaactgga agcggaagaa 2800

 caccaaaagc atgaattttg acaacccagt ctacaggaaa acaacagaag 2850

 aagaagatga agatgagctc catataggga gaactgctca gattggccat 2900

 gtctatcctg cagcaatcag cagctttgat cgcccactgt gggcagagcc 2950

 ctgtcttggg gagaccagag aaccggaaga cccagcccct gccctcaagg 3000

 agctttttgt cttgccgggg gaaccaaggt cacagctgca ccaactcccg 3050

 aagaaccctc tttccgagct gcctgtcgtc aaatccaagc gagtggcatt 3100

 aagccttgaa gatgatggac taccctgagg atgggatcac ccccttcgtg 3150

 cctcatggaa ttcagtccca tgcactacac tctggatggt gtatgactgg 3200

 atgaatgggt ttctatatat gggtctgtgt gagtgtatgt gtgtgtgtga 3250

 tttttttttt aaatttatgt tgcggaaagg taaccacaaa gttatgatga 3300

 actgcaaaca tccaaaggat gtgagagttt ttctatgtat aatgttttat 3350

 acacttttta actggttgca ctacccatga ggaattcgtg gaatggctac 3400

 tgctgactaa catgatgcac ataaccaaat gggggccaat ggcacagtac 3450

 cttactcatc atttaaaaac tatatttaca gaagatgttt ggttgctggg 3500

 ggggcttttt tgggttttgg ggcatttgtt ttttgtaaat aagatgatta 3550

 tgctttgtgg ctatccatca acataagtaa aaaaaaaaaa aaaacacttc 3600

 aactccctcc cccatttaga ttatttatta acatatttta aaaatcagat 3650

 gagttctata aataatttag agaagtgaga gtatttattt ttggcatgtt 3700

 tggcccacca cacagactct gtgtgtgtat gtgtgtgttt atatgtgtat 3750

 gtgtgtgaca ggaaaatctg tagagaagag gcacatctat ggctactgtt 3800

 caaatacata aagataaatt tattttcaca cagtccacaa ggggtatatc 3850

 ttgtagtttt cagaaaagcc tttggaaatc tggatcagga aatagatacc 3900

 atggtttgtg caattatgta gtaaaaaagg caaatctttt cacctctggc 3950

 tattcctgag accccaggaa gtcaggaaaa gcctttcagc tcacccatgg 4000

 ctgctgtgac tcctaccagg gctttcttgg ctttggcgaa ggtcagtgta 4050

 cagacattcc atggtaccag agtgctcaga aagtcaagat aggatatgcc 4100

 tcaccctcag ctactccttg ttttaaagtt cagctctttg agtaacttct 4150

 tcaatttctt tcaggacact tgggttgaat tcagtaagtt tcctctgaag 4200

 caccctgaag ggtgccatcc ttacagagct aagtggagac gtttccagat 4250

 cagcccaagt ttactataga gactggccca ggcactgaat gtctaggaca 4300

 tgctgtggat gaagataaag atggtggaat aggttttatc acatctctta 4350

 tttctctttt ccccttactc tctaccattt cctttatgtg gggaaacatt 4400

 ttaaggtaat aaataggtta cttaccatca tatgttcata tagatgaaac 4450

 taatttttgg cttaagtcag aacaactggc ccccaattga agtcatattt 4500

 gtggggggaa atggcatacg caatattata ttatattgga tatttatgtt 4550

 cacacaggaa tttggtttac tgctttgtaa ataaaaggga aaactccggg 4600

 tatatgt 4607

<210> 1764
<211> 963
<212> PRT
<213> Homo sapien

<400> 1764
 Met Gly Leu Pro Glu Pro Gly Pro Leu Arg Leu Leu Ala Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Leu Leu Leu Leu Leu Arg Leu Gln His Leu Ala
                  20                  25                  30

 Ala Ala Ala Ala Asp Pro Leu Leu Gly Gly Gln Gly Pro Ala Lys
                  35                  40                  45

 Glu Cys Glu Lys Asp Gln Phe Gln Cys Arg Asn Glu Arg Cys Ile
                  50                  55                  60

 Pro Ser Val Trp Arg Cys Asp Glu Asp Asp Asp Cys Leu Asp His
                  65                  70                  75

 Ser Asp Glu Asp Asp Cys Pro Lys Lys Thr Cys Ala Asp Ser Asp
                  80                  85                  90

 Phe Thr Cys Asp Asn Gly His Cys Ile His Glu Arg Trp Lys Cys
                  95                 100                 105

 Asp Gly Glu Glu Glu Cys Pro Asp Gly Ser Asp Glu Ser Glu Ala
                 110                 115                 120

 Thr Cys Thr Lys Gln Val Cys Pro Ala Glu Lys Leu Ser Cys Gly
                 125                 130                 135

 Pro Thr Ser His Lys Cys Val Pro Ala Ser Trp Arg Cys Asp Gly
                 140                 145                 150

 Glu Lys Asp Cys Glu Gly Gly Ala Asp Glu Ala Gly Cys Ala Thr
                 155                 160                 165

 Leu Cys Ala Pro His Glu Phe Gln Cys Gly Asn Arg Ser Cys Leu
                 170                 175                 180

 Ala Ala Val Phe Val Cys Asp Gly Asp Asp Asp Cys Gly Asp Gly
                 185                 190                 195

 Ser Asp Glu Arg Gly Cys Ala Asp Pro Ala Cys Gly Pro Arg Glu
                 200                 205                 210

 Phe Arg Cys Gly Gly Asp Gly Gly Gly Ala Cys Ile Pro Glu Arg
                 215                 220                 225

 Trp Val Cys Asp Arg Gln Phe Asp Cys Glu Asp Arg Ser Asp Glu
                 230                 235                 240

 Ala Ala Glu Leu Cys Gly Arg Pro Gly Pro Gly Ala Thr Ser Ala
                 245                 250                 255

 Pro Ala Ala Cys Ala Thr Val Ser Gln Phe Ala Cys Arg Ser Gly
                 260                 265                 270

 Glu Cys Val His Leu Gly Trp Arg Cys Asp Gly Asp Arg Asp Cys
                 275                 280                 285

 Lys Asp Lys Ser Asp Glu Ala Asp Cys Pro Leu Gly Thr Cys Arg
                 290                 295                 300

 Gly Asp Glu Phe Gln Cys Gly Asp Gly Thr Cys Val Leu Ala Ile
                 305                 310                 315

 Lys His Cys Asn Gln Glu Gln Asp Cys Pro Asp Gly Ser Asp Glu
                 320                 325                 330

 Ala Gly Cys Leu Gln Gly Leu Asn Glu Cys Leu His Asn Asn Gly
                 335                 340                 345

 Gly Cys Ser His Ile Cys Thr Asp Leu Lys Ile Gly Phe Glu Cys
                 350                 355                 360

 Thr Cys Pro Ala Gly Phe Gln Leu Leu Asp Gln Lys Thr Cys Gly
                 365                 370                 375

 Asp Ile Asp Glu Cys Lys Asp Pro Asp Ala Cys Ser Gln Ile Cys
                 380                 385                 390

 Val Asn Tyr Lys Gly Tyr Phe Lys Cys Glu Cys Tyr Pro Gly Tyr
                 395                 400                 405

 Glu Met Asp Leu Leu Thr Lys Asn Cys Lys Ala Ala Gly Gly Lys
                 410                 415                 420

 Ser Pro Ser Leu Ile Phe Thr Asn Arg Tyr Glu Val Arg Arg Ile
                 425                 430                 435

 Asp Leu Val Lys Arg Asn Tyr Ser Arg Leu Ile Pro Met Leu Lys
                 440                 445                 450

 Asn Val Val Ala Leu Asp Val Glu Val Ala Thr Asn Arg Ile Tyr
                 455                 460                 465

 Trp Cys Asp Leu Ser Tyr Arg Lys Ile Tyr Ser Ala Tyr Met Asp
                 470                 475                 480

 Lys Ala Ser Asp Pro Lys Glu Gln Glu Val Leu Ile Asp Glu Gln
                 485                 490                 495

 Leu His Ser Pro Glu Gly Leu Ala Val Asp Trp Val His Lys His
                 500                 505                 510

 Ile Tyr Trp Thr Asp Ser Gly Asn Lys Thr Ile Ser Val Ala Thr
                 515                 520                 525

 Val Asp Gly Gly Arg Arg Arg Thr Leu Phe Ser Arg Asn Leu Ser
                 530                 535                 540

 Glu Pro Arg Ala Ile Ala Val Asp Pro Leu Arg Gly Phe Met Tyr
                 545                 550                 555

 Trp Ser Asp Trp Gly Asp Gln Ala Lys Ile Glu Lys Ser Gly Leu
                 560                 565                 570

 Asn Gly Val Asp Arg Gln Thr Leu Val Ser Asp Asn Ile Glu Trp
                 575                 580                 585

 Pro Asn Gly Ile Thr Leu Asp Leu Leu Ser Gln Arg Leu Tyr Trp
                 590                 595                 600

 Val Asp Ser Lys Leu His Gln Leu Ser Ser Ile Asp Phe Ser Gly
                 605                 610                 615

 Gly Asn Arg Lys Thr Leu Ile Ser Ser Thr Asp Phe Leu Ser His
                 620                 625                 630

 Pro Phe Gly Ile Ala Val Phe Glu Asp Lys Val Phe Trp Thr Asp
                 635                 640                 645

 Leu Glu Asn Glu Ala Ile Phe Ser Ala Asn Arg Leu Asn Gly Leu
                 650                 655                 660

 Glu Ile Ser Ile Leu Ala Glu Asn Leu Asn Asn Pro His Asp Ile
                 665                 670                 675

 Val Ile Phe His Glu Leu Lys Gln Pro Arg Ala Pro Asp Ala Cys
                 680                 685                 690

 Glu Leu Ser Val Gln Pro Asn Gly Gly Cys Glu Tyr Leu Cys Leu
                 695                 700                 705

 Pro Ala Pro Gln Ile Ser Ser His Ser Pro Lys Tyr Thr Cys Ala
                 710                 715                 720

 Cys Pro Asp Thr Met Trp Leu Gly Pro Asp Met Lys Arg Cys Tyr
                 725                 730                 735

 Arg Ala Pro Gln Ser Thr Ser Thr Thr Thr Leu Ala Ser Thr Met
                 740                 745                 750

 Thr Arg Thr Val Pro Ala Thr Thr Arg Ala Pro Gly Thr Thr Val
                 755                 760                 765

 His Arg Ser Thr Tyr Gln Asn His Ser Thr Glu Thr Pro Ser Leu
                 770                 775                 780

 Thr Ala Ala Val Pro Ser Ser Val Ser Val Pro Arg Ala Pro Ser
                 785                 790                 795

 Ile Ser Pro Ser Thr Leu Ser Pro Ala Thr Ser Asn His Ser Gln
                 800                 805                 810

 His Tyr Ala Asn Glu Asp Ser Lys Met Gly Ser Thr Val Thr Ala
                 815                 820                 825

 Ala Val Ile Gly Ile Ile Val Pro Ile Val Val Ile Ala Leu Leu
                 830                 835                 840

 Cys Met Ser Gly Tyr Leu Ile Trp Arg Asn Trp Lys Arg Lys Asn
                 845                 850                 855

 Thr Lys Ser Met Asn Phe Asp Asn Pro Val Tyr Arg Lys Thr Thr
                 860                 865                 870

 Glu Glu Glu Asp Glu Asp Glu Leu His Ile Gly Arg Thr Ala Gln
                 875                 880                 885

 Ile Gly His Val Tyr Pro Ala Ala Ile Ser Ser Phe Asp Arg Pro
                 890                 895                 900

 Leu Trp Ala Glu Pro Cys Leu Gly Glu Thr Arg Glu Pro Glu Asp
                 905                 910                 915

 Pro Ala Pro Ala Leu Lys Glu Leu Phe Val Leu Pro Gly Glu Pro
                 920                 925                 930

 Arg Ser Gln Leu His Gln Leu Pro Lys Asn Pro Leu Ser Glu Leu
                 935                 940                 945

 Pro Val Val Lys Ser Lys Arg Val Ala Leu Ser Leu Glu Asp Asp
                 950                 955                 960

 Gly Leu Pro


<210> 1765
<211> 1940
<212> DNA
<213> Homo sapien

<400> 1765
 acccagggtc cggcctgcgc cttcccgcca ggcctggaca ctggttcaac 50

 acctgtgact tcatgtgtgc gcgccggcca cacctgcagt cacacctgta 100

 gccccctctg ccaagagatc cataccgagg cagcgtcggt ggctacaagc 150

 cctcagtcca cacctgtgga cacctgtgac acctggccac acgacctgtg 200

 gccgcggcct ggcgtctgct gcgacaggag cccttacctc ccctgttata 250

 acacctgaca gccacctaac tgcccctgca gaaggagcaa tggccttggc 300

 tcctgagagg taagagcccg gcccaccctc tccagatgcc agtccccgag 350

 cgccctgcag ccggccctga ctctccgcgg ccgggcaccc gcagggcagc 400

 cccacgcgtg ctgttcggag agtggctcct tggagagatc agcagcggct 450

 gctatgaggg gctgcagtgg ctggacgagg cccgcacctg tttccgcgtg 500

 ccctggaagc acttcgcgcg caaggacctg agcgaggccg acgcgcgcat 550

 cttcaaggcc tgggctgtgg cccgcggcag gtggccgcct agcagcaggg 600

 gaggtggccc gccccccgag gctgagactg cggagcgcgc cggctggaaa 650

 accaacttcc gctgcgcact gcgcagcacg cgtcgcttcg tgatgctgcg 700

 agataactcg ggggacccgg ccgacccgca caaggtgtac gcgctcagcc 750

 gggagctgtg ctggcgagaa ggcccaggca cggaccagac tgaggcagag 800

 gcccccgcag ctgtcccacc accacagggt gggcccccag ggccattcct 850

 ggcacacaca catgctggac tccaagcccc aggccccctc cctgccccag 900

 ctggtgacga gggggacctc ctgctccagg cagtgcaaca gagctgcctg 950

 gcagaccatc tgctgacagc gtcatggggg gcagatccag tcccaaccaa 1000

 ggctcctgga gagggacaag aagggcttcc cctgactggg gcctgtgctg 1050

 gaggcccagg gctccctgct ggggagctgt acgggtgggc agtagagacg 1100

 acccccagcc ccgggcccca gcccgcggca ctaacgacag gcgaggccgc 1150

 ggccccagag tccccgcacc aggcagagcc gtacctgtca ccctccccaa 1200

 gcgcctgcac cgcggtgcaa gagcccagcc caggggcgct ggacgtgacc 1250

 atcatgtaca agggccgcac ggtgctgcag aaggtggtgg gacacccgag 1300

 ctgcacgttc ctatacggcc ccccagaccc agctgtccgg gccacagacc 1350

 cccagcaggt agcattcccc agccctgccg agctcccgga ccagaagcag 1400

 ctgcgctaca cggaggaact gctgcggcac gtggcccctg ggttgcacct 1450

 ggagcttcgg gggccacagc tgtgggcccg gcgcatgggc aagtgcaagg 1500

 tgtactggga ggtgggcggc cccccaggct ccgccagccc ctccacccca 1550

 gcctgcctgc tgcctcggaa ctgtgacacc cccatcttcg acttcagagt 1600

 cttcttccga gagctggtgg aattccgggc acggcagcgc cgtggctccc 1650

 cacgctatac catctacctg ggcttcgggc aggacctgtc agctgggagg 1700

 cccaaggaga agagcctggt cctggtgaag ctggaaccct ggctgtgccg 1750

 agtgcaccta gagggcacgc agcgtgaggg tgtgtcttcc ctggatagca 1800

 gcagcctcag cctctgcctg tccagcgcca acagcctcta tgacgacatc 1850

 gagtgcttcc ttatggagct ggagcagccc gcctagaacc cagtctaatg 1900

 agaactccag aaagctggag cagcccacct agagctggcc 1940

<210> 1766
<211> 516
<212> PRT
<213> Homo sapien

<400> 1766
 Met Pro Val Pro Glu Arg Pro Ala Ala Gly Pro Asp Ser Pro Arg
   1               5                  10                  15

 Pro Gly Thr Arg Arg Ala Ala Pro Arg Val Leu Phe Gly Glu Trp
                  20                  25                  30

 Leu Leu Gly Glu Ile Ser Ser Gly Cys Tyr Glu Gly Leu Gln Trp
                  35                  40                  45

 Leu Asp Glu Ala Arg Thr Cys Phe Arg Val Pro Trp Lys His Phe
                  50                  55                  60

 Ala Arg Lys Asp Leu Ser Glu Ala Asp Ala Arg Ile Phe Lys Ala
                  65                  70                  75

 Trp Ala Val Ala Arg Gly Arg Trp Pro Pro Ser Ser Arg Gly Gly
                  80                  85                  90

 Gly Pro Pro Pro Glu Ala Glu Thr Ala Glu Arg Ala Gly Trp Lys
                  95                 100                 105

 Thr Asn Phe Arg Cys Ala Leu Arg Ser Thr Arg Arg Phe Val Met
                 110                 115                 120

 Leu Arg Asp Asn Ser Gly Asp Pro Ala Asp Pro His Lys Val Tyr
                 125                 130                 135

 Ala Leu Ser Arg Glu Leu Cys Trp Arg Glu Gly Pro Gly Thr Asp
                 140                 145                 150

 Gln Thr Glu Ala Glu Ala Pro Ala Ala Val Pro Pro Pro Gln Gly
                 155                 160                 165

 Gly Pro Pro Gly Pro Phe Leu Ala His Thr His Ala Gly Leu Gln
                 170                 175                 180

 Ala Pro Gly Pro Leu Pro Ala Pro Ala Gly Asp Glu Gly Asp Leu
                 185                 190                 195

 Leu Leu Gln Ala Val Gln Gln Ser Cys Leu Ala Asp His Leu Leu
                 200                 205                 210

 Thr Ala Ser Trp Gly Ala Asp Pro Val Pro Thr Lys Ala Pro Gly
                 215                 220                 225

 Glu Gly Gln Glu Gly Leu Pro Leu Thr Gly Ala Cys Ala Gly Gly
                 230                 235                 240

 Pro Gly Leu Pro Ala Gly Glu Leu Tyr Gly Trp Ala Val Glu Thr
                 245                 250                 255

 Thr Pro Ser Pro Gly Pro Gln Pro Ala Ala Leu Thr Thr Gly Glu
                 260                 265                 270

 Ala Ala Ala Pro Glu Ser Pro His Gln Ala Glu Pro Tyr Leu Ser
                 275                 280                 285

 Pro Ser Pro Ser Ala Cys Thr Ala Val Gln Glu Pro Ser Pro Gly
                 290                 295                 300

 Ala Leu Asp Val Thr Ile Met Tyr Lys Gly Arg Thr Val Leu Gln
                 305                 310                 315

 Lys Val Val Gly His Pro Ser Cys Thr Phe Leu Tyr Gly Pro Pro
                 320                 325                 330

 Asp Pro Ala Val Arg Ala Thr Asp Pro Gln Gln Val Ala Phe Pro
                 335                 340                 345

 Ser Pro Ala Glu Leu Pro Asp Gln Lys Gln Leu Arg Tyr Thr Glu
                 350                 355                 360

 Glu Leu Leu Arg His Val Ala Pro Gly Leu His Leu Glu Leu Arg
                 365                 370                 375

 Gly Pro Gln Leu Trp Ala Arg Arg Met Gly Lys Cys Lys Val Tyr
                 380                 385                 390

 Trp Glu Val Gly Gly Pro Pro Gly Ser Ala Ser Pro Ser Thr Pro
                 395                 400                 405

 Ala Cys Leu Leu Pro Arg Asn Cys Asp Thr Pro Ile Phe Asp Phe
                 410                 415                 420

 Arg Val Phe Phe Arg Glu Leu Val Glu Phe Arg Ala Arg Gln Arg
                 425                 430                 435

 Arg Gly Ser Pro Arg Tyr Thr Ile Tyr Leu Gly Phe Gly Gln Asp
                 440                 445                 450

 Leu Ser Ala Gly Arg Pro Lys Glu Lys Ser Leu Val Leu Val Lys
                 455                 460                 465

 Leu Glu Pro Trp Leu Cys Arg Val His Leu Glu Gly Thr Gln Arg
                 470                 475                 480

 Glu Gly Val Ser Ser Leu Asp Ser Ser Ser Leu Ser Leu Cys Leu
                 485                 490                 495

 Ser Ser Ala Asn Ser Leu Tyr Asp Asp Ile Glu Cys Phe Leu Met
                 500                 505                 510

 Glu Leu Glu Gln Pro Ala
                 515

<210> 1767
<211> 9886
<212> DNA
<213> Homo sapien

<400> 1767
 gcgagaggag tcgggatctg cgctgcagcc accgccgcgg ttgatactac 50

 tttgaccttc cgagtgcagt gaggcataca tcacaatttg gaattatgca 100

 ttggtttatc aatttacttg tttattgtca ccctgctgcc cagatatgac 150

 ttcatgagga cagtgatgtg tgttctgaaa ttgtgaacca tgagtctagt 200

 acttaatgat ctgcttatct gctgccgtca actagaacat gatagagcta 250

 cagaacgaaa gaaagaagtt gagaaattta agcgcctgat tcgagatcct 300

 gaaacaatta aacatctaga tcggcattca gattccaaac aaggaaaata 350

 tttgaattgg gatgctgttt ttagattttt acagaaatat attcagaaag 400

 aaacagaatg tctgagaata gcaaaaccaa atgtatcagc ctcaacacaa 450

 gcctccaggc agaaaaagat gcaggaaatc agtagtttgg tcaaatactt 500

 catcaaatgt gcaaacagaa gagcacctag gctaaaatgt caagaactct 550

 taaattatat catggataca gtgaaagatt catctaatgg tgctatttac 600

 ggagctgatt gtagcaacat actactcaaa gacattcttt ctgtgagaaa 650

 atactggtgt gaaatatctc agcaacagtg gttagaattg ttctctgtgt 700

 acttcaggct ctatctgaaa ccttcacaag atgttcatag agttttagtg 750

 gctagaataa ttcatgctgt taccaaagga tgctgttctc agactgacgg 800

 attaaattcc aaatttttgg actttttttc caaggctatt cagtgtgcga 850

 gacaagaaaa gagctcttca ggtctaaatc atatcttagc agctcttact 900

 atcttcctca agactttggc tgtcaacttt cgaattcgag tgtgtgaatt 950

 aggagatgaa attcttccca ctttgcttta tatttggact caacataggc 1000

 ttaatgattc tttaaaagaa gtcattattg aattatttca actgcaaatt 1050

 tatatccatc atccgaaagg agccaaaacc caagaaaaag gtgcttatga 1100

 atcaacaaaa tggagaagta ttttatacaa cttatatgat ctgctagtga 1150

 atgagataag tcatatagga agtagaggaa agtattcttc aggatttcgt 1200

 aatattgccg tcaaagaaaa tttgattgaa ttgatggcag atatctgtca 1250

 ccaggttttt aatgaagata ccagatcctt ggagatttct caatcttaca 1300

 ctactacaca aagagaatct agtgattaca gtgtcccttg caaaaggaag 1350

 aaaatagaac taggctggga agtaataaaa gatcaccttc agaagtcaca 1400

 gaatgatttt gatcttgtgc cttggctaca gattgcaacc caattaatat 1450

 caaagtatcc tgcaagttta cctaactgtg agctgtctcc attactgatg 1500

 atactatctc agcttctacc ccaacagcga catggggaac gtacaccata 1550

 tgtgttacga tgccttacgg aagttgcatt gtgtcaagac aagaggtcaa 1600

 acctagaaag ctcacaaaag tcagatttat taaaactctg gaataaaatt 1650

 tggtgtatta cctttcgtgg tataagttct gagcaaatac aagctgaaaa 1700

 ctttggctta cttggagcca taattcaggg tagtttagtt gaggttgaca 1750

 gagaattctg gaagttattt actgggtcag cctgcagacc ttcatgtcct 1800

 gcagtatgct gtttgacttt ggcactgacc accagtatag ttccaggagc 1850

 ggtaaaaatg ggaatagagc aaaatatgtg tgaagtaaat agaagctttt 1900

 ctttaaagga atcaataatg aaatggctct tattctatca gttagagggt 1950

 gacttagaaa atagcacaga agtgcctcca attcttcaca gtaattttcc 2000

 tcatcttgta ctggagaaaa ttcttgtgag tctcactatg aaaaactgta 2050

 aagctgcaat gaattttttc caaagcgtgc cagaatgtga acaccaccaa 2100

 aaagataaag aagaactttc attctcagaa gtagaagaac tatttcttca 2150

 gacaactttt gacaagatgg actttttaac cattgtgaga gaatgtggta 2200

 tagaaaagca ccagtccagt attggcttct ctgtccacca gaatctcaag 2250

 gaatcactgg atcgctgtct tctgggatta tcagaacagc ttctgaataa 2300

 ttactcatct gagattacaa attcagaaac tcttgtccgg tgttcacgtc 2350

 ttttggtggg tgtccttggc tgctactgtt acatgggtgt aatagctgaa 2400

 gaggaagcat ataagtcaga attattccag aaagccaact ctctaatgca 2450

 atgtgcagga gaaagtatca ctctgtttaa aaataagaca aatgaggaat 2500

 tcagaattgg ttccttgaga aatatgatgc agctatgtac acgttgcttg 2550

 agcaactgta ccaagaagag tccaaataag attgcatctg gctttttcct 2600

 gcgattgtta acatcaaagc taatgaatga cattgcagat atttgtaaaa 2650

 gtttagcatc cttcatcaaa aagccatttg accgtggaga agtagaatca 2700

 atggaagatg atactaatgg aaatctaatg gaggtggagg atcagtcatc 2750

 catgaatcta tttaacgatt accctgatag tagtgttagt gatgcaaacg 2800

 aacctggaga gagccaaagt accataggtg ccattaatcc tttagctgaa 2850

 gaatatctgt caaagcaaga tctacttttc ttagacatgc tcaagttctt 2900

 gtgtttgtgt gtaactactg ctcagaccaa tactgtgtcc tttagggcag 2950

 ctgatattcg gaggaaattg ttaatgttaa ttgattctag cacgctagaa 3000

 cctaccaaat ccctccacct gcatatgtat ctaatgcttt taaaggagct 3050

 tcctggagaa gagtacccct tgccaatgga agatgttctt gaacttctga 3100

 aaccactatc caatgtgtgt tctttgtatc gtcgtgacca agatgtttgt 3150

 aaaactattt taaaccatgt ccttcatgta gtgaaaaacc taggtcaaag 3200

 caatatggac tctgagaaca caagggatgc tcaaggacag tttcttacag 3250

 taattggagc attttggcat ctaacaaagg agaggaaata tatattctct 3300

 gtaagaatgg ccctagtaaa ttgccttaaa actttgcttg aggctgatcc 3350

 ttattcaaaa tgggccattc ttaatgtaat gggaaaagac tttcctgtaa 3400

 atgaagtatt tacacaattt cttgctgaca atcatcacca agttcgcatg 3450

 ttggctgcag agtcaatcaa tagattgttc caggacacga agggagattc 3500

 ttccaggtta ctgaaagcac ttcctttgaa gcttcagcaa acagcttttg 3550

 aaaatgcata cttgaaagct caggaaggaa tgagagaaat gtcccatagt 3600

 gctgagaacc ctgaaacttt ggatgaaatt tataatagaa aatctgtttt 3650

 actgacgttg atagctgtgg ttttatcctg tagccctatc tgcgaaaaac 3700

 aggctttgtt tgccctgtgt aaatctgtga aagagaatgg attagaacct 3750

 caccttgtga aaaaggtttt agagaaagtt tctgaaactt ttggatatag 3800

 acgtttagaa gactttatgg catctcattt agattatctg gttttggaat 3850

 ggctaaatct tcaagatact gaatacaact tatcttcttt tccttttatt 3900

 ttattaaact acacaaatat tgaggatttc tatagatctt gttataaggt 3950

 tttgattcca catctggtga ttagaagtca ttttgatgag gtgaagtcca 4000

 ttgctaatca gattcaagag gactggaaaa gtcttctaac agactgcttt 4050

 ccaaagattc ttgtaaatat tcttccttat tttgcctatg agggtaccag 4100

 agacagtggg atggcacagc aaagagagac tgctaccaag gtctatgata 4150

 tgcttaaaag tgaaaactta ttgggaaaac agattgatca cttattcatt 4200

 agtaatttac cagagattgt ggtggagtta ttgatgacgt tacatgagcc 4250

 agcaaattct agtgccagtc agagcactga cctctgtgac ttttcagggg 4300

 atttggatcc tgctcctaat ccacctcatt ttccatcgca tgtgattaaa 4350

 gcaacatttg cctatatcag caattgtcat aaaaccaagt taaaaagcat 4400

 tttagaaatt ctttccaaaa gccctgattc ctatcagaaa attcttcttg 4450

 ccatatgtga gcaagcagct gaaacaaata atgtttataa gaagcacaga 4500

 attcttaaaa tatatcacct gtttgttagt ttattactga aagatataaa 4550

 aagtggctta ggaggagctt gggcctttgt tcttcgagac gttatttata 4600

 ctttgattca ctatatcaac caaaggcctt cttgtatcat ggatgtgtca 4650

 ttacgtagct tctccctttg ttgtgactta ttaagtcagg tttgccagac 4700

 agccgtgact tactgtaagg atgctctaga aaaccatctt catgttattg 4750

 ttggtacact tatacccctt gtgtatgagc aggtggaggt tcagaaacag 4800

 gtattggact tgttgaaata cttagtgata gataacaagg ataatgaaaa 4850

 cctctatatc acgattaagc ttttagatcc ttttcctgac catgttgttt 4900

 ttaaggattt gcgtattact cagcaaaaaa tcaaatacag tagaggaccc 4950

 ttttcactct tggaggaaat taaccatttt ctctcagtaa gtgtttatga 5000

 tgcacttcca ttgacaagac ttgaaggact aaaggatctt cgaagacaac 5050

 tggaactaca taaagatcag atggtggaca ttatgagagc ttctcaggat 5100

 aatccgcaag atgggattat ggtgaaacta gttgtcaatt tgttgcagtt 5150

 atccaagatg gcaataaacc acactggtga aaaagaagtt ctagaggctg 5200

 ttggaagctg cttgggagaa gtgggtccta tagatttctc taccatagct 5250

 atacaacata gtaaagatgc atcttatacc aaggccctta agttatttga 5300

 agataaagaa cttcagtgga ccttcataat gctgacctac ctgaataaca 5350

 cactggtaga agattgtgtc aaagttcgat cagcagctgt tacctgtttg 5400

 aaaaacattt tagccacaaa gactggacat agtttctggg agatttataa 5450

 gatgacaaca gatccaatgc tggcctatct acagcctttt agaacatcaa 5500

 gaaaaaagtt tttagaagta cccagatttg acaaagaaaa cccttttgaa 5550

 ggcctggatg atataaatct gtggattcct ctaagtgaaa atcatgacat 5600

 ttggataaag acactgactt gtgctttttt ggacagtgga ggcacaaaat 5650

 gtgaaattct tcaattatta aagccaatgt gtgaagtgaa aactgacttt 5700

 tgtcagactg tacttccata cttgattcat gatattttac tccaagatac 5750

 aaatgaatca tggagaaatc tgctttctac acatgttcag ggatttttca 5800

 ccagctgtct tcgacacttc tcgcaaacga gccgatccac aacccctgca 5850

 aacttggatt cagagtcaga gcactttttc cgatgctgtt tggataaaaa 5900

 atcacaaaga acaatgcttg ctgttgtgga ctacatgaga agacaaaaga 5950

 gaccttcttc aggaacaatt tttaatgatg ctttctggct ggatttaaat 6000

 tatctagaag ttgccaaggt agctcagtct tgtgctgctc actttacagc 6050

 tttactctat gcagaaatct atgcagataa gaaaagtatg gatgatcaag 6100

 agaaaagaag tcttgcattt gaagaaggaa gccagagtac aactatttct 6150

 agcttgagtg aaaaaagtaa agaagaaact ggaataagtt tacaggatct 6200

 tctcttagaa atctacagaa gtatagggga gccagatagt ttgtatggct 6250

 gtggtggagg gaagatgtta caacccatta ctagactacg aacatatgaa 6300

 cacgaagcaa tgtggggcaa agccctagta acatatgacc tcgaaacagc 6350

 aatcccctca tcaacacgcc aggcaggaat cattcaggcc ttgcagaatt 6400

 tgggactctg ccatattctt tccgtctatt taaaaggatt ggattatgaa 6450

 aataaagact ggtgtcctga actagaagaa cttcattacc aagcagcatg 6500

 gaggaatatg cagtgggacc attgcacttc cgtcagcaaa gaagtagaag 6550

 gaaccagtta ccatgaatca ttgtacaatg ctctacaatc tctaagagac 6600

 agagaattct ctacatttta tgaaagtctc aaatatgcca gagtaaaaga 6650

 agtggaagag atgtgtaagc gcagccttga gtctgtgtat tcgctctatc 6700

 ccacacttag caggttgcag gccattggag agctggaaag cattggggag 6750

 cttttctcaa gatcagtcac acatagacaa ctctctgaag tatatattaa 6800

 gtggcagaaa cactcccagc ttctcaagga cagtgatttt agttttcagg 6850

 agcctatcat ggctctacgc acagtcattt tggagatcct gatggaaaag 6900

 gaaatggaca actcacaaag agaatgtatt aaggacattc tcaccaaaca 6950

 ccttgtagaa ctctctatac tggccagaac tttcaagaac actcagctcc 7000

 ctgaaagggc aatatttcaa attaaacagt acaattcagt tagctgtgga 7050

 gtctctgagt ggcagctgga agaagcacaa gtattctggg caaaaaagga 7100

 gcagagtctt gccctgagta ttctcaagca aatgatcaag aagttggatg 7150

 ccagctgtgc agcgaacaat cccagcctaa aacttacata cacagaatgt 7200

 ctgagggttt gtggcaactg gttagcagaa acgtgcttag aaaatcctgc 7250

 ggtcatcatg cagacctatc tagaaaaggc agtagaagtt gctggaaatt 7300

 atgatggaga aagtagtgat gagctaagaa atggaaaaat gaaggcattt 7350

 ctctcattag cccggttttc agatactcaa taccaaagaa ttgaaaacta 7400

 catgaaatca tcggaatttg aaaacaagca agctctcctg aaaagagcca 7450

 aagaggaagt aggtctcctt agggaacata aaattcagac aaacagatac 7500

 acagtaaagg ttcagcgaga gctggagttg gatgaattag ccctgcgtgc 7550

 actgaaagag gatcgtaaac gcttcttatg taaagcagtt gaaaattata 7600

 tcaactgctt attaagtgga gaagaacatg atatgtgggt attccggctt 7650

 tgttccctct ggcttgaaaa ttctggagtt tctgaagtca atggcatgat 7700

 gaagagagac ggaatgaaga ttccaacata taaatttttg cctcttatgt 7750

 accaattggc tgctagaatg gggaccaaga tgatgggagg cctaggattt 7800

 catgaagtcc tcaataatct aatctctaga atttcaatgg atcaccccca 7850

 tcacactttg tttattatac tggccttagc aaatgcaaac agagatgaat 7900

 ttctgactaa accagaggta gccagaagaa gcagaataac taaaaatgtg 7950

 cctaaacaaa gctctcagct tgatgaggat cgaacagagg ctgcaaatag 8000

 aataatatgt actatcagaa gtaggagacc tcagatggtc agaagtgttg 8050

 aggcactttg tgatgcttat attatattag caaacttaga tgccactcag 8100

 tggaagactc agagaaaagg cataaatatt ccagcagacc agccaattac 8150

 taaacttaag aatttagaag atgttgttgt ccctactatg gaaattaagg 8200

 tggaccacac aggagaatat ggaaatctgg tgactataca gtcatttaaa 8250

 gcagaatttc gcttagcagg aggtgtaaat ttaccaaaaa taatagattg 8300

 tgtaggttcc gatggcaagg agaggagaca gcttgttaag ggccgtgatg 8350

 acctgagaca agatgctgtc atgcaacagg tcttccagat gtgtaataca 8400

 ttactgcaga gaaacacgga aactaggaag aggaaattaa ctatctgtac 8450

 ttataaggtg gttcccctct ctcagcgaag tggtgttctt gaatggtgca 8500

 caggaactgt ccccattggt gaatttcttg ttaacaatga agatggtgct 8550

 cataaaagat acaggccaaa tgatttcagt gcctttcagt gccaaaagaa 8600

 aatgatggag gtgcaaaaaa agtcttttga agagaaatat gaagtcttca 8650

 tggatgtttg ccaaaatttt caaccagttt tccgttactt ctgcatggaa 8700

 aaattcttgg atccagctat ttggtttgag aagcgattgg cttatacgcg 8750

 cagtgtagct acttcttcta ttgttggtta catacttgga cttggtgata 8800

 gacatgtaca gaatatcttg ataaatgagc agtcagcaga acttgtacat 8850

 atagatctag gtgttgcttt tgaacagggc aaaatccttc ctactcctga 8900

 gacagttcct tttagactca ccagagatat tgtggatggc atgggcatta 8950

 cgggtgttga aggtgtcttc agaagatgct gtgagaaaac catggaagtg 9000

 atgagaaact ctcaggaaac tctgttaacc attgtagagg tccttctata 9050

 tgatccactc tttgactgga ccatgaatcc tttgaaagct ttgtatttac 9100

 agcagaggcc ggaagatgaa actgagcttc accctactct gaatgcagat 9150

 gaccaagaat gcaaacgaaa tctcagtgat attgaccaga gtttcaacaa 9200

 agtagctgaa cgtgtcttaa tgagactaca agagaaactg aaaggagtgg 9250

 aagaaggcac tgtgctcagt gttggtggac aagtgaattt gctcatacag 9300

 caggccatag accccaaaaa tctcagccga cttttcccag gatggaaagc 9350

 ttgggtgtga tcttcagtat atgaattacc ctttcattca gcctttagaa 9400

 attatatttt agcctttatt tttaacctgc caacatactt taagtaggga 9450

 ttaatattta agtgaactat tgtgggtttt tttgaatgtt ggttttaata 9500

 cttgatttaa tcaccactca aaaatgtttt gatggtctta aggaacatct 9550

 ctgctttcac tctttagaaa taatggtcat tcgggctggg cgcagcggct 9600

 cacgcctgta atcccagcac tttgggaggc cgaggtgagc ggatcacaag 9650

 gtcaggagtt cgagaccagc ctggccaaga gaccagcctg gccagtatgg 9700

 tgaaaccctg tctctactaa aaatacaaaa attagccgag catggtggcg 9750

 ggcacctgta gtcccagcta ctcgagaggc tgaggcagga gaatctcttg 9800

 aacctgggag gtgaaggttg ctgtgggcca aaatcatgcc attgcactcc 9850

 agcctgggtg acaagagcga aactccatct caaaaa 9886

<210> 1768
<211> 2000
<212> PRT
<213> Homo sapien

<400> 1768
 Met Ser Leu Val Leu Asn Asp Leu Leu Ile Cys Cys Arg Gln Leu
   1               5                  10                  15

 Glu His Asp Arg Ala Thr Glu Arg Lys Lys Glu Val Glu Lys Phe
                  20                  25                  30

 Lys Arg Leu Ile Arg Asp Pro Glu Thr Ile Lys His Leu Asp Arg
                  35                  40                  45

 His Ser Asp Ser Lys Gln Gly Lys Tyr Leu Asn Trp Asp Ala Val
                  50                  55                  60

 Phe Arg Phe Leu Gln Lys Tyr Ile Gln Lys Glu Thr Glu Cys Leu
                  65                  70                  75

 Arg Ile Ala Lys Pro Asn Val Ser Ala Ser Thr Gln Ala Ser Arg
                  80                  85                  90

 Gln Lys Lys Met Gln Glu Ile Ser Ser Leu Val Lys Tyr Phe Ile
                  95                 100                 105

 Lys Cys Ala Asn Arg Arg Ala Pro Arg Leu Lys Cys Gln Glu Leu
                 110                 115                 120

 Leu Asn Tyr Ile Met Asp Thr Val Lys Asp Ser Ser Asn Gly Ala
                 125                 130                 135

 Ile Tyr Gly Ala Asp Cys Ser Asn Ile Leu Leu Lys Asp Ile Leu
                 140                 145                 150

 Ser Val Arg Lys Tyr Trp Cys Glu Ile Ser Gln Gln Gln Trp Leu
                 155                 160                 165

 Glu Leu Phe Ser Val Tyr Phe Arg Leu Tyr Leu Lys Pro Ser Gln
                 170                 175                 180

 Asp Val His Arg Val Leu Val Ala Arg Ile Ile His Ala Val Thr
                 185                 190                 195

 Lys Gly Cys Cys Ser Gln Thr Asp Gly Leu Asn Ser Lys Phe Leu
                 200                 205                 210

 Asp Phe Phe Ser Lys Ala Ile Gln Cys Ala Arg Gln Glu Lys Ser
                 215                 220                 225

 Ser Ser Gly Leu Asn His Ile Leu Ala Ala Leu Thr Ile Phe Leu
                 230                 235                 240

 Lys Thr Leu Ala Val Asn Phe Arg Ile Arg Val Cys Glu Leu Gly
                 245                 250                 255

 Asp Glu Ile Leu Pro Thr Leu Leu Tyr Ile Trp Thr Gln His Arg
                 260                 265                 270

 Leu Asn Asp Ser Leu Lys Glu Val Ile Ile Glu Leu Phe Gln Leu
                 275                 280                 285

 Gln Ile Tyr Ile His His Pro Lys Gly Ala Lys Thr Gln Glu Lys
                 290                 295                 300

 Gly Ala Tyr Glu Ser Thr Lys Trp Arg Ser Ile Leu Tyr Asn Leu
                 305                 310                 315

 Tyr Asp Leu Leu Val Asn Glu Ile Ser His Ile Gly Ser Arg Gly
                 320                 325                 330

 Lys Tyr Ser Ser Gly Phe Arg Asn Ile Ala Val Lys Glu Asn Leu
                 335                 340                 345

 Ile Glu Leu Met Ala Asp Ile Cys His Gln Val Phe Asn Glu Asp
                 350                 355                 360

 Thr Arg Ser Leu Glu Ile Ser Gln Ser Tyr Thr Thr Thr Gln Arg
                 365                 370                 375

 Glu Ser Ser Asp Tyr Ser Val Pro Cys Lys Arg Lys Lys Ile Glu
                 380                 385                 390

 Leu Gly Trp Glu Val Ile Lys Asp His Leu Gln Lys Ser Gln Asn
                 395                 400                 405

 Asp Phe Asp Leu Val Pro Trp Leu Gln Ile Ala Thr Gln Leu Ile
                 410                 415                 420

 Ser Lys Tyr Pro Ala Ser Leu Pro Asn Cys Glu Leu Ser Pro Leu
                 425                 430                 435

 Leu Met Ile Leu Ser Gln Leu Leu Pro Gln Gln Arg His Gly Glu
                 440                 445                 450

 Arg Thr Pro Tyr Val Leu Arg Cys Leu Thr Glu Val Ala Leu Cys
                 455                 460                 465

 Gln Asp Lys Arg Ser Asn Leu Glu Ser Ser Gln Lys Ser Asp Leu
                 470                 475                 480

 Leu Lys Leu Trp Asn Lys Ile Trp Cys Ile Thr Phe Arg Gly Ile
                 485                 490                 495

 Ser Ser Glu Gln Ile Gln Ala Glu Asn Phe Gly Leu Leu Gly Ala
                 500                 505                 510

 Ile Ile Gln Gly Ser Leu Val Glu Val Asp Arg Glu Phe Trp Lys
                 515                 520                 525

 Leu Phe Thr Gly Ser Ala Cys Arg Pro Ser Cys Pro Ala Val Cys
                 530                 535                 540

 Cys Leu Thr Leu Ala Leu Thr Thr Ser Ile Val Pro Gly Ala Val
                 545                 550                 555

 Lys Met Gly Ile Glu Gln Asn Met Cys Glu Val Asn Arg Ser Phe
                 560                 565                 570

 Ser Leu Lys Glu Ser Ile Met Lys Trp Leu Leu Phe Tyr Gln Leu
                 575                 580                 585

 Glu Gly Asp Leu Glu Asn Ser Thr Glu Val Pro Pro Ile Leu His
                 590                 595                 600

 Ser Asn Phe Pro His Leu Val Leu Glu Lys Ile Leu Val Ser Leu
                 605                 610                 615

 Thr Met Lys Asn Cys Lys Ala Ala Met Asn Phe Phe Gln Ser Val
                 620                 625                 630

 Pro Glu Cys Glu His His Gln Lys Asp Lys Glu Glu Leu Ser Phe
                 635                 640                 645

 Ser Glu Val Glu Glu Leu Phe Leu Gln Thr Thr Phe Asp Lys Met
                 650                 655                 660

 Asp Phe Leu Thr Ile Val Arg Glu Cys Gly Ile Glu Lys His Gln
                 665                 670                 675

 Ser Ser Ile Gly Phe Ser Val His Gln Asn Leu Lys Glu Ser Leu
                 680                 685                 690

 Asp Arg Cys Leu Leu Gly Leu Ser Glu Gln Leu Leu Asn Asn Tyr
                 695                 700                 705

 Ser Ser Glu Ile Thr Asn Ser Glu Thr Leu Val Arg Cys Ser Arg
                 710                 715                 720

 Leu Leu Val Gly Val Leu Gly Cys Tyr Cys Tyr Met Gly Val Ile
                 725                 730                 735

 Ala Glu Glu Glu Ala Tyr Lys Ser Glu Leu Phe Gln Lys Ala Asn
                 740                 745                 750

 Ser Leu Met Gln Cys Ala Gly Glu Ser Ile Thr Leu Phe Lys Asn
                 755                 760                 765

 Lys Thr Asn Glu Glu Phe Arg Ile Gly Ser Leu Arg Asn Met Met
                 770                 775                 780

 Gln Leu Cys Thr Arg Cys Leu Ser Asn Cys Thr Lys Lys Ser Pro
                 785                 790                 795

 Asn Lys Ile Ala Ser Gly Phe Phe Leu Arg Leu Leu Thr Ser Lys
                 800                 805                 810

 Leu Met Asn Asp Ile Ala Asp Ile Cys Lys Ser Leu Ala Ser Phe
                 815                 820                 825

 Ile Lys Lys Pro Phe Asp Arg Gly Glu Val Glu Ser Met Glu Asp
                 830                 835                 840

 Asp Thr Asn Gly Asn Leu Met Glu Val Glu Asp Gln Ser Ser Met
                 845                 850                 855

 Asn Leu Phe Asn Asp Tyr Pro Asp Ser Ser Val Ser Asp Ala Asn
                 860                 865                 870

 Glu Pro Gly Glu Ser Gln Ser Thr Ile Gly Ala Ile Asn Pro Leu
                 875                 880                 885

 Ala Glu Glu Tyr Leu Ser Lys Gln Asp Leu Leu Phe Leu Asp Met
                 890                 895                 900

 Leu Lys Phe Leu Cys Leu Cys Val Thr Thr Ala Gln Thr Asn Thr
                 905                 910                 915

 Val Ser Phe Arg Ala Ala Asp Ile Arg Arg Lys Leu Leu Met Leu
                 920                 925                 930

 Ile Asp Ser Ser Thr Leu Glu Pro Thr Lys Ser Leu His Leu His
                 935                 940                 945

 Met Tyr Leu Met Leu Leu Lys Glu Leu Pro Gly Glu Glu Tyr Pro
                 950                 955                 960

 Leu Pro Met Glu Asp Val Leu Glu Leu Leu Lys Pro Leu Ser Asn
                 965                 970                 975

 Val Cys Ser Leu Tyr Arg Arg Asp Gln Asp Val Cys Lys Thr Ile
                 980                 985                 990

 Leu Asn His Val Leu His Val Val Lys Asn Leu Gly Gln Ser Asn
                 995                1000                1005

 Met Asp Ser Glu Asn Thr Arg Asp Ala Gln Gly Gln Phe Leu Thr
                1010                1015                1020

 Val Ile Gly Ala Phe Trp His Leu Thr Lys Glu Arg Lys Tyr Ile
                1025                1030                1035

 Phe Ser Val Arg Met Ala Leu Val Asn Cys Leu Lys Thr Leu Leu
                1040                1045                1050

 Glu Ala Asp Pro Tyr Ser Lys Trp Ala Ile Leu Asn Val Met Gly
                1055                1060                1065

 Lys Asp Phe Pro Val Asn Glu Val Phe Thr Gln Phe Leu Ala Asp
                1070                1075                1080

 Asn His His Gln Val Arg Met Leu Ala Ala Glu Ser Ile Asn Arg
                1085                1090                1095

 Leu Phe Gln Asp Thr Lys Gly Asp Ser Ser Arg Leu Leu Lys Ala
                1100                1105                1110

 Leu Pro Leu Lys Leu Gln Gln Thr Ala Phe Glu Asn Ala Tyr Leu
                1115                1120                1125

 Lys Ala Gln Glu Gly Met Arg Glu Met Ser His Ser Ala Glu Asn
                1130                1135                1140

 Pro Glu Thr Leu Asp Glu Ile Tyr Asn Arg Lys Ser Val Leu Leu
                1145                1150                1155

 Thr Leu Ile Ala Val Val Leu Ser Cys Ser Pro Ile Cys Glu Lys
                1160                1165                1170

 Gln Ala Leu Phe Ala Leu Cys Lys Ser Val Lys Glu Asn Gly Leu
                1175                1180                1185

 Glu Pro His Leu Val Lys Lys Val Leu Glu Lys Val Ser Glu Thr
                1190                1195                1200

 Phe Gly Tyr Arg Arg Leu Glu Asp Phe Met Ala Ser His Leu Asp
                1205                1210                1215

 Tyr Leu Val Leu Glu Trp Leu Asn Leu Gln Asp Thr Glu Tyr Asn
                1220                1225                1230

 Leu Ser Ser Phe Pro Phe Ile Leu Leu Asn Tyr Thr Asn Ile Glu
                1235                1240                1245

 Asp Phe Tyr Arg Ser Cys Tyr Lys Val Leu Ile Pro His Leu Val
                1250                1255                1260

 Ile Arg Ser His Phe Asp Glu Val Lys Ser Ile Ala Asn Gln Ile
                1265                1270                1275

 Gln Glu Asp Trp Lys Ser Leu Leu Thr Asp Cys Phe Pro Lys Ile
                1280                1285                1290

 Leu Val Asn Ile Leu Pro Tyr Phe Ala Tyr Glu Gly Thr Arg Asp
                1295                1300                1305

 Ser Gly Met Ala Gln Gln Arg Glu Thr Ala Thr Lys Val Tyr Asp
                1310                1315                1320

 Met Leu Lys Ser Glu Asn Leu Leu Gly Lys Gln Ile Asp His Leu
                1325                1330                1335

 Phe Ile Ser Asn Leu Pro Glu Ile Val Val Glu Leu Leu Met Thr
                1340                1345                1350

 Leu His Glu Pro Ala Asn Ser Ser Ala Ser Gln Ser Thr Asp Leu
                1355                1360                1365

 Cys Asp Phe Ser Gly Asp Leu Asp Pro Ala Pro Asn Pro Pro His
                1370                1375                1380

 Phe Pro Ser His Val Ile Lys Ala Thr Phe Ala Tyr Ile Ser Asn
                1385                1390                1395

 Cys His Lys Thr Lys Leu Lys Ser Ile Leu Glu Ile Leu Ser Lys
                1400                1405                1410

 Ser Pro Asp Ser Tyr Gln Lys Ile Leu Leu Ala Ile Cys Glu Gln
                1415                1420                1425

 Ala Ala Glu Thr Asn Asn Val Tyr Lys Lys His Arg Ile Leu Lys
                1430                1435                1440

 Ile Tyr His Leu Phe Val Ser Leu Leu Leu Lys Asp Ile Lys Ser
                1445                1450                1455

 Gly Leu Gly Gly Ala Trp Ala Phe Val Leu Arg Asp Val Ile Tyr
                1460                1465                1470

 Thr Leu Ile His Tyr Ile Asn Gln Arg Pro Ser Cys Ile Met Asp
                1475                1480                1485

 Val Ser Leu Arg Ser Phe Ser Leu Cys Cys Asp Leu Leu Ser Gln
                1490                1495                1500

 Val Cys Gln Thr Ala Val Thr Tyr Cys Lys Asp Ala Leu Glu Asn
                1505                1510                1515

 His Leu His Val Ile Val Gly Thr Leu Ile Pro Leu Val Tyr Glu
                1520                1525                1530

 Gln Val Glu Val Gln Lys Gln Val Leu Asp Leu Leu Lys Tyr Leu
                1535                1540                1545

 Val Ile Asp Asn Lys Asp Asn Glu Asn Leu Tyr Ile Thr Ile Lys
                1550                1555                1560

 Leu Leu Asp Pro Phe Pro Asp His Val Val Phe Lys Asp Leu Arg
                1565                1570                1575

 Ile Thr Gln Gln Lys Ile Lys Tyr Ser Arg Gly Pro Phe Ser Leu
                1580                1585                1590

 Leu Glu Glu Ile Asn His Phe Leu Ser Val Ser Val Tyr Asp Ala
                1595                1600                1605

 Leu Pro Leu Thr Arg Leu Glu Gly Leu Lys Asp Leu Arg Arg Gln
                1610                1615                1620

 Leu Glu Leu His Lys Asp Gln Met Val Asp Ile Met Arg Ala Ser
                1625                1630                1635

 Gln Asp Asn Pro Gln Asp Gly Ile Met Val Lys Leu Val Val Asn
                1640                1645                1650

 Leu Leu Gln Leu Ser Lys Met Ala Ile Asn His Thr Gly Glu Lys
                1655                1660                1665

 Glu Val Leu Glu Ala Val Gly Ser Cys Leu Gly Glu Val Gly Pro
                1670                1675                1680

 Ile Asp Phe Ser Thr Ile Ala Ile Gln His Ser Lys Asp Ala Ser
                1685                1690                1695

 Tyr Thr Lys Ala Leu Lys Leu Phe Glu Asp Lys Glu Leu Gln Trp
                1700                1705                1710

 Thr Phe Ile Met Leu Thr Tyr Leu Asn Asn Thr Leu Val Glu Asp
                1715                1720                1725

 Cys Val Lys Val Arg Ser Ala Ala Val Thr Cys Leu Lys Asn Ile
                1730                1735                1740

 Leu Ala Thr Lys Thr Gly His Ser Phe Trp Glu Ile Tyr Lys Met
                1745                1750                1755

 Thr Thr Asp Pro Met Leu Ala Tyr Leu Gln Pro Phe Arg Thr Ser
                1760                1765                1770

 Arg Lys Lys Phe Leu Glu Val Pro Arg Phe Asp Lys Glu Asn Pro
                1775                1780                1785

 Phe Glu Gly Leu Asp Asp Ile Asn Leu Trp Ile Pro Leu Ser Glu
                1790                1795                1800

 Asn His Asp Ile Trp Ile Lys Thr Leu Thr Cys Ala Phe Leu Asp
                1805                1810                1815

 Ser Gly Gly Thr Lys Cys Glu Ile Leu Gln Leu Leu Lys Pro Met
                1820                1825                1830

 Cys Glu Val Lys Thr Asp Phe Cys Gln Thr Val Leu Pro Tyr Leu
                1835                1840                1845

 Ile His Asp Ile Leu Leu Gln Asp Thr Asn Glu Ser Trp Arg Asn
                1850                1855                1860

 Leu Leu Ser Thr His Val Gln Gly Phe Phe Thr Ser Cys Leu Arg
                1865                1870                1875

 His Phe Ser Gln Thr Ser Arg Ser Thr Thr Pro Ala Asn Leu Asp
                1880                1885                1890

 Ser Glu Ser Glu His Phe Phe Arg Cys Cys Leu Asp Lys Lys Ser
                1895                1900                1905

 Gln Arg Thr Met Leu Ala Val Val Asp Tyr Met Arg Arg Gln Lys
                1910                1915                1920

 Arg Pro Ser Ser Gly Thr Ile Phe Asn Asp Ala Phe Trp Leu Asp
                1925                1930                1935

 Leu Asn Tyr Leu Glu Val Ala Lys Val Ala Gln Ser Cys Ala Ala
                1940                1945                1950

 His Phe Thr Ala Leu Leu Tyr Ala Glu Ile Tyr Ala Asp Lys Lys
                1955                1960                1965

 Ser Met Asp Asp Gln Glu Lys Arg Ser Leu Ala Phe Glu Glu Gly
                1970                1975                1980

 Ser Gln Ser Thr Thr Ile Ser Ser Leu Ser Glu Lys Ser Lys Glu
                1985                1990                1995

 Glu Thr Gly Ile Ser
                2000

<210> 1769
<211> 1410
<212> DNA
<213> Homo sapien

<400> 1769
 cgcgcctcgg gcggtaccca gccagtcccc agcgccgcgc taccgcgctg 50

 accggccctc cagacgcctc ccggtacccg ggaccccagc ccggccgctc 100

 gcccgcagcc cgccggccgc acacgtcccc ggagccgggc ctagggcggg 150

 cggcagcggc ggctcggcgc agtcaggctg ggctctgtag cgtccccatg 200

 gccgcggccg gctggcggga cggctccggc caggagaagt accggctcgt 250

 ggtggtcggc gggggcggcg tgggcaagtc ggcgctcacc atccagttca 300

 tccagtccta ttttgtaacg gattatgatc caaccattga agattcttac 350

 acaaagcagt gtgtgataga tgacagagca gcccggctag atattttgga 400

 tacagcagga caagaagagt ttggagccat gagagaacag tatatgagga 450

 ctggcgaagg cttcctgttg gtcttttcag tcacagatag aggcagtttt 500

 gaagaaatct ataagtttca aagacagatt ctcagagtaa aggatcgtga 550

 tgagttccca atgattttaa ttggtaataa agcagatctg gatcatcaaa 600

 gacaggtaac acaggaagaa ggacaacagt tagcacggca gcttaaggta 650

 acatacatgg aggcatcagc aaagattagg atgaatgtag atcaagcttt 700

 ccatgaactt gtccgggtta tcaggaaatt tcaagagcag gaatgtcctc 750

 cttcaccaga accaacacgg aaagaaaaag acaagaaagg ctgccattgt 800

 gtcattttct agaatccctt cagttttagc taccaacggc caggaaaagc 850

 cctcatcttc tctttctctc ctcagtttac atcttgttgg tacctttcta 900

 gccttagaca aatgatcacc atgttagcct tagaccaaga agctggctag 950

 tcctttctgt gaagctaata caatggtcat ttccagacaa atttaaagga 1000

 aacactaagg ctgcttcaaa gattatctga ttcctttaaa atatatgtct 1050

 atatacacag acatgctctt tttttaagtg cttacatttt aatagagatg 1100

 aatcagtttt ggaatctaag ctgtttgcca agctgaagct acaggttgtg 1150

 aaataatttt taacttttgg aatcatactg cctactgtta ctctaaatag 1200

 aaatataggg ttttttttaa tgtgaatttt tgcctatctt taaacatttc 1250

 aatgtcagcc tttgttaacc ttaaatacac tgaattgaat ctacaaaagt 1300

 gaaccatctc agacctttac tgatactaca acttttgttt tctgatggcc 1350

 aaaataccaa atgcctgttg tatttatgga ttaaaaactg cttataaaaa 1400

 aaaaaaaaaa 1410

<210> 1770
<211> 204
<212> PRT
<213> Homo sapien

<400> 1770
 Met Ala Ala Ala Gly Trp Arg Asp Gly Ser Gly Gln Glu Lys Tyr
   1               5                  10                  15

 Arg Leu Val Val Val Gly Gly Gly Gly Val Gly Lys Ser Ala Leu
                  20                  25                  30

 Thr Ile Gln Phe Ile Gln Ser Tyr Phe Val Thr Asp Tyr Asp Pro
                  35                  40                  45

 Thr Ile Glu Asp Ser Tyr Thr Lys Gln Cys Val Ile Asp Asp Arg
                  50                  55                  60

 Ala Ala Arg Leu Asp Ile Leu Asp Thr Ala Gly Gln Glu Glu Phe
                  65                  70                  75

 Gly Ala Met Arg Glu Gln Tyr Met Arg Thr Gly Glu Gly Phe Leu
                  80                  85                  90

 Leu Val Phe Ser Val Thr Asp Arg Gly Ser Phe Glu Glu Ile Tyr
                  95                 100                 105

 Lys Phe Gln Arg Gln Ile Leu Arg Val Lys Asp Arg Asp Glu Phe
                 110                 115                 120

 Pro Met Ile Leu Ile Gly Asn Lys Ala Asp Leu Asp His Gln Arg
                 125                 130                 135

 Gln Val Thr Gln Glu Glu Gly Gln Gln Leu Ala Arg Gln Leu Lys
                 140                 145                 150

 Val Thr Tyr Met Glu Ala Ser Ala Lys Ile Arg Met Asn Val Asp
                 155                 160                 165

 Gln Ala Phe His Glu Leu Val Arg Val Ile Arg Lys Phe Gln Glu
                 170                 175                 180

 Gln Glu Cys Pro Pro Ser Pro Glu Pro Thr Arg Lys Glu Lys Asp
                 185                 190                 195

 Lys Lys Gly Cys His Cys Val Ile Phe
                 200

<210> 1771
<211> 874
<212> DNA
<213> Homo sapien

<400> 1771
 gctgcggccg cccgcgcgga cccggcgaga ggcggcggcg ggagcggcgg 50

 tgatggacgg gtccggggag cagcccagag gcggggggcc caccagctct 100

 gagcagatca tgaagacagg ggcccttttg cttcagggtt tcatccagga 150

 tcgagcaggg cgaatggggg gggaggcacc cgagctggcc ctggacccgg 200

 tgcctcagga tgcgtccacc aagaagctga gcgagtgtct caagcgcatc 250

 ggggacgaac tggacagtaa catggagctg cagaggatga ttgccgccgt 300

 ggacacagac tccccccgag aggtcttttt ccgagtggca gctgacatgt 350

 tttctgacgg caacttcaac tggggccggg ttgtcgccct tttctacttt 400

 gccagcaaac tggtgctcaa ggccctgtgc accaaggtgc cggaactgat 450

 cagaaccatc atgggctgga cattggactt cctccgggag cggctgttgg 500

 gctggatcca agaccagggt ggttgggtga gactcctcaa gcctcctcac 550

 ccccaccacc gcgccctcac caccgcccct gccccaccgt ccctgccccc 600

 cgccactcct ctgggaccct gggccttctg gagcaggtca cagtggtgcc 650

 ctctccccat cttcagatca tcagatgtgg tctataatgc gttttcctta 700

 cgtgtctgat caatccccga ttcatctacc ctgctgacct cccagtgacc 750

 cctgacctca ctgtgacctt gacttgatta gtgccttctg ccctccctgg 800

 agcctccact gcctctggaa ttgctcaagt tcattgatga ccctctgacc 850

 ctagctcttt cctttttttt tttt 874

<210> 1772
<211> 218
<212> PRT
<213> Homo sapien

<400> 1772
 Met Asp Gly Ser Gly Glu Gln Pro Arg Gly Gly Gly Pro Thr Ser
   1               5                  10                  15

 Ser Glu Gln Ile Met Lys Thr Gly Ala Leu Leu Leu Gln Gly Phe
                  20                  25                  30

 Ile Gln Asp Arg Ala Gly Arg Met Gly Gly Glu Ala Pro Glu Leu
                  35                  40                  45

 Ala Leu Asp Pro Val Pro Gln Asp Ala Ser Thr Lys Lys Leu Ser
                  50                  55                  60

 Glu Cys Leu Lys Arg Ile Gly Asp Glu Leu Asp Ser Asn Met Glu
                  65                  70                  75

 Leu Gln Arg Met Ile Ala Ala Val Asp Thr Asp Ser Pro Arg Glu
                  80                  85                  90

 Val Phe Phe Arg Val Ala Ala Asp Met Phe Ser Asp Gly Asn Phe
                  95                 100                 105

 Asn Trp Gly Arg Val Val Ala Leu Phe Tyr Phe Ala Ser Lys Leu
                 110                 115                 120

 Val Leu Lys Ala Leu Cys Thr Lys Val Pro Glu Leu Ile Arg Thr
                 125                 130                 135

 Ile Met Gly Trp Thr Leu Asp Phe Leu Arg Glu Arg Leu Leu Gly
                 140                 145                 150

 Trp Ile Gln Asp Gln Gly Gly Trp Val Arg Leu Leu Lys Pro Pro
                 155                 160                 165

 His Pro His His Arg Ala Leu Thr Thr Ala Pro Ala Pro Pro Ser
                 170                 175                 180

 Leu Pro Pro Ala Thr Pro Leu Gly Pro Trp Ala Phe Trp Ser Arg
                 185                 190                 195

 Ser Gln Trp Cys Pro Leu Pro Ile Phe Arg Ser Ser Asp Val Val
                 200                 205                 210

 Tyr Asn Ala Phe Ser Leu Arg Val
                 215

<210> 1773
<211> 1542
<212> DNA
<213> Homo sapien

<400> 1773
 ctcctcttca ctcgcgagcc ctcggacatg gtggcccccg gctccgtgac 50

 cagccggctg ggctcggtat tccccttcct gctagtcctg gtggatctgc 100

 agtacgaagg tgctgaatgt ggagtaaatg cagatgttga gaaacatctt 150

 gaattgggca agaaattact tgcagctgga cagctagctg atgctttatc 200

 tcagtttcat gctgccgtag atggtgaccc tgataactat attgcttatt 250

 atcggagggc tactgtcttt ttagctatgg gcaaatcaaa agctgcactt 300

 cctgatttaa ctaaagtgat tcaattgaag atggacttca ctgcagcaag 350

 attacagaga ggtcacttat tactcaaaca aggaaaactt gatgaagcag 400

 aagatgattt taaaaaagtg ctcaaatcta atccaagtga aaatgaagaa 450

 aaggaagcac agtctcaact tataaaatct gatgaaatgc agcgtttgcg 500

 ttcacaagca cttaacgctt ttggaagtgg agattatact gctgctatag 550

 ccttccttga taagatttta gaggtttgtg tttgggatgc agaactacgg 600

 gaacttcgag ctgaatgttt tataaaagaa ggagaaccta ggaaagctat 650

 aagtgactta aaagctgcgt caaagttgaa gaatgataat actgaagcgt 700

 tttataaaat aagcacactg tactaccaac taggagacca cgaactgtcc 750

 ctcagtgaag ttcgggaatg tcttaaactt gaccaggatc ataaaaggtg 800

 ttttgcacac tataaacaag taaagaaact taataagctg attgagtcag 850

 ctgaagagct catcagagat ggcagataca cagatgctac cagcaaatat 900

 gaatctgtca tgaaaacaga gccaagcatt gctgaatata cagttcgttc 950

 aaaggagagg atttgccact gcttttctaa ggacgagaag cctgttgaag 1000

 ctattagggt ttgttctgaa gttttacaga tggaacctga caatgtgaat 1050

 gccctgaaag atcgagcaga ggcctatttg atagaggaaa tgtatgatga 1100

 agctattcag gattatgaaa ctgctcagga acacaatgaa aatgatcagc 1150

 agattcgaga aggtctagag aaagcacaaa gattattgaa acagtcgcag 1200

 aaacgagatt attataaaat cttgggagta aaaagaaatg ccaaaaagca 1250

 agaaattatt aaagcatacc gaaaattagc actgcagtgg cacccagata 1300

 acttccagaa tgaagaagaa aagaaaaaag ctgagaaaaa gttcattgat 1350

 atagcagctg ctaaagaagt cctctctgat ccagaaatga gaaagaagtt 1400

 tgacgacgga gaagatcctt tggatgcaga gagccagcaa ggaggcggcg 1450

 gcaacccttt ccacagaagc tggaactcat ggcaagggtt caatcccttc 1500

 agctcaggcg gaccatttag atttaaattc cacttcaatt aa 1542

<210> 1774
<211> 504
<212> PRT
<213> Homo sapien

<400> 1774
 Met Val Ala Pro Gly Ser Val Thr Ser Arg Leu Gly Ser Val Phe
   1               5                  10                  15

 Pro Phe Leu Leu Val Leu Val Asp Leu Gln Tyr Glu Gly Ala Glu
                  20                  25                  30

 Cys Gly Val Asn Ala Asp Val Glu Lys His Leu Glu Leu Gly Lys
                  35                  40                  45

 Lys Leu Leu Ala Ala Gly Gln Leu Ala Asp Ala Leu Ser Gln Phe
                  50                  55                  60

 His Ala Ala Val Asp Gly Asp Pro Asp Asn Tyr Ile Ala Tyr Tyr
                  65                  70                  75

 Arg Arg Ala Thr Val Phe Leu Ala Met Gly Lys Ser Lys Ala Ala
                  80                  85                  90

 Leu Pro Asp Leu Thr Lys Val Ile Gln Leu Lys Met Asp Phe Thr
                  95                 100                 105

 Ala Ala Arg Leu Gln Arg Gly His Leu Leu Leu Lys Gln Gly Lys
                 110                 115                 120

 Leu Asp Glu Ala Glu Asp Asp Phe Lys Lys Val Leu Lys Ser Asn
                 125                 130                 135

 Pro Ser Glu Asn Glu Glu Lys Glu Ala Gln Ser Gln Leu Ile Lys
                 140                 145                 150

 Ser Asp Glu Met Gln Arg Leu Arg Ser Gln Ala Leu Asn Ala Phe
                 155                 160                 165

 Gly Ser Gly Asp Tyr Thr Ala Ala Ile Ala Phe Leu Asp Lys Ile
                 170                 175                 180

 Leu Glu Val Cys Val Trp Asp Ala Glu Leu Arg Glu Leu Arg Ala
                 185                 190                 195

 Glu Cys Phe Ile Lys Glu Gly Glu Pro Arg Lys Ala Ile Ser Asp
                 200                 205                 210

 Leu Lys Ala Ala Ser Lys Leu Lys Asn Asp Asn Thr Glu Ala Phe
                 215                 220                 225

 Tyr Lys Ile Ser Thr Leu Tyr Tyr Gln Leu Gly Asp His Glu Leu
                 230                 235                 240

 Ser Leu Ser Glu Val Arg Glu Cys Leu Lys Leu Asp Gln Asp His
                 245                 250                 255

 Lys Arg Cys Phe Ala His Tyr Lys Gln Val Lys Lys Leu Asn Lys
                 260                 265                 270

 Leu Ile Glu Ser Ala Glu Glu Leu Ile Arg Asp Gly Arg Tyr Thr
                 275                 280                 285

 Asp Ala Thr Ser Lys Tyr Glu Ser Val Met Lys Thr Glu Pro Ser
                 290                 295                 300

 Ile Ala Glu Tyr Thr Val Arg Ser Lys Glu Arg Ile Cys His Cys
                 305                 310                 315

 Phe Ser Lys Asp Glu Lys Pro Val Glu Ala Ile Arg Val Cys Ser
                 320                 325                 330

 Glu Val Leu Gln Met Glu Pro Asp Asn Val Asn Ala Leu Lys Asp
                 335                 340                 345

 Arg Ala Glu Ala Tyr Leu Ile Glu Glu Met Tyr Asp Glu Ala Ile
                 350                 355                 360

 Gln Asp Tyr Glu Thr Ala Gln Glu His Asn Glu Asn Asp Gln Gln
                 365                 370                 375

 Ile Arg Glu Gly Leu Glu Lys Ala Gln Arg Leu Leu Lys Gln Ser
                 380                 385                 390

 Gln Lys Arg Asp Tyr Tyr Lys Ile Leu Gly Val Lys Arg Asn Ala
                 395                 400                 405

 Lys Lys Gln Glu Ile Ile Lys Ala Tyr Arg Lys Leu Ala Leu Gln
                 410                 415                 420

 Trp His Pro Asp Asn Phe Gln Asn Glu Glu Glu Lys Lys Lys Ala
                 425                 430                 435

 Glu Lys Lys Phe Ile Asp Ile Ala Ala Ala Lys Glu Val Leu Ser
                 440                 445                 450

 Asp Pro Glu Met Arg Lys Lys Phe Asp Asp Gly Glu Asp Pro Leu
                 455                 460                 465

 Asp Ala Glu Ser Gln Gln Gly Gly Gly Gly Asn Pro Phe His Arg
                 470                 475                 480

 Ser Trp Asn Ser Trp Gln Gly Phe Asn Pro Phe Ser Ser Gly Gly
                 485                 490                 495

 Pro Phe Arg Phe Lys Phe His Phe Asn
                 500

<210> 1775
<211> 1083
<212> DNA
<213> Homo sapien

<400> 1775
 atggacccag aagaaacttc agtttatttg gattattact atgctacgag 50

 cccaaactct gacatcaggg agacccactc ccatgttcct tacacctctg 100

 tcttccttcc agtcttttac acagctgtgt tcctgactgg agtgctgggg 150

 aaccttgttc tcatgggagc gttgcatttc aaacccggca gccgaagact 200

 gatcgacatc tttatcatca atctggctgc ctctgacttc atttttcttg 250

 tcacattgcc tctctgggtg gataaagaag catctctagg actgtggagg 300

 acgggctcct tcctgtgcaa agggagctcc tacatgatct ccgtcaatat 350

 gcactgcagt gtcctcctgc tcacttgcat gagtgttgac cgctacctgg 400

 ccattgtgtg gccagtcgta tccaggaaat tcagaaggac agactgtgca 450

 tatgtagtct gtgccagcat ctggtttatc tcctgcctgc tggggttgcc 500

 tactcttctg tccagggagc tcacgctgat tgatgataag ccatactgtg 550

 cagagaaaaa ggcaactcca attaaactca tatggtccct ggtggcctta 600

 attttcacct tttttgtccc tttgttgagc attgtgacct gctactgttg 650

 cattgcaagg aagctgtgtg cccattacca gcaatcagga aagcacaaca 700

 aaaagctgaa gaaatctata aagatcatct ttattgtcgt ggcagccttt 750

 cttgtctcct ggctgccctt caatactttc aagttcctgg ccattgtctc 800

 tgggttgcgg caagaacact atttaccctc agctattctt cagcttggta 850

 tggaggtgag tggacccttg gcatttgcca acagctgtgt caaccctttc 900

 atttactata tcttcgacag ctacatccgc cgggccattg tccactgctt 950

 gtgcccttgc ctgaaaaact atgactttgg gagtagcact gagacatcag 1000

 atagtcacct cactaaggct ctctccacct tcattcatgc agaagatttt 1050

 gccaggagga ggaagaggtc tgtgtcactc taa 1083

<210> 1776
<211> 360
<212> PRT
<213> Homo sapien

<400> 1776
 Met Asp Pro Glu Glu Thr Ser Val Tyr Leu Asp Tyr Tyr Tyr Ala
   1               5                  10                  15

 Thr Ser Pro Asn Ser Asp Ile Arg Glu Thr His Ser His Val Pro
                  20                  25                  30

 Tyr Thr Ser Val Phe Leu Pro Val Phe Tyr Thr Ala Val Phe Leu
                  35                  40                  45

 Thr Gly Val Leu Gly Asn Leu Val Leu Met Gly Ala Leu His Phe
                  50                  55                  60

 Lys Pro Gly Ser Arg Arg Leu Ile Asp Ile Phe Ile Ile Asn Leu
                  65                  70                  75

 Ala Ala Ser Asp Phe Ile Phe Leu Val Thr Leu Pro Leu Trp Val
                  80                  85                  90

 Asp Lys Glu Ala Ser Leu Gly Leu Trp Arg Thr Gly Ser Phe Leu
                  95                 100                 105

 Cys Lys Gly Ser Ser Tyr Met Ile Ser Val Asn Met His Cys Ser
                 110                 115                 120

 Val Leu Leu Leu Thr Cys Met Ser Val Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val Trp Pro Val Val Ser Arg Lys Phe Arg Arg Thr Asp Cys Ala
                 140                 145                 150

 Tyr Val Val Cys Ala Ser Ile Trp Phe Ile Ser Cys Leu Leu Gly
                 155                 160                 165

 Leu Pro Thr Leu Leu Ser Arg Glu Leu Thr Leu Ile Asp Asp Lys
                 170                 175                 180

 Pro Tyr Cys Ala Glu Lys Lys Ala Thr Pro Ile Lys Leu Ile Trp
                 185                 190                 195

 Ser Leu Val Ala Leu Ile Phe Thr Phe Phe Val Pro Leu Leu Ser
                 200                 205                 210

 Ile Val Thr Cys Tyr Cys Cys Ile Ala Arg Lys Leu Cys Ala His
                 215                 220                 225

 Tyr Gln Gln Ser Gly Lys His Asn Lys Lys Leu Lys Lys Ser Ile
                 230                 235                 240

 Lys Ile Ile Phe Ile Val Val Ala Ala Phe Leu Val Ser Trp Leu
                 245                 250                 255

 Pro Phe Asn Thr Phe Lys Phe Leu Ala Ile Val Ser Gly Leu Arg
                 260                 265                 270

 Gln Glu His Tyr Leu Pro Ser Ala Ile Leu Gln Leu Gly Met Glu
                 275                 280                 285

 Val Ser Gly Pro Leu Ala Phe Ala Asn Ser Cys Val Asn Pro Phe
                 290                 295                 300

 Ile Tyr Tyr Ile Phe Asp Ser Tyr Ile Arg Arg Ala Ile Val His
                 305                 310                 315

 Cys Leu Cys Pro Cys Leu Lys Asn Tyr Asp Phe Gly Ser Ser Thr
                 320                 325                 330

 Glu Thr Ser Asp Ser His Leu Thr Lys Ala Leu Ser Thr Phe Ile
                 335                 340                 345

 His Ala Glu Asp Phe Ala Arg Arg Arg Lys Arg Ser Val Ser Leu
                 350                 355                 360

<210> 1777
<211> 597
<212> DNA
<213> Homo sapien

<400> 1777
 atggcaaagc aaccttctga tgtaagttct gagtgtgacc gagaaggtag 50

 acaattgcag cctgcggaga ggcctcccca gctcagacct ggggccccta 100

 cctccctaca gacagagcca caaggtaatc ctgaaggcaa tcacggaggt 150

 gaaggggaca gctgccccca cggcagccct cagggcccgc tggccccacc 200

 tgccagccct ggcccttttg ctaccagatc cccgcttttc atctttatga 250

 gaagatcctc cctgctgtct cgatcctcca gtgggtattt ctcttttgac 300

 acagacagga gcccagcacc catgagttgt gacaaatcaa cacaaacccc 350

 aagtcctcct tgccaggcct tcaaccacta tctcagtgca atggcttcca 400

 tgaggcaggc tgaacctgca gatatgcgcc cagagatatg gatcgcccaa 450

 gagttgcggc gtatcggaga cgagtttaac gcttactatg caaggagggt 500

 atttttgaat aattaccaag cagccgaaga ccacccacga atggttatct 550

 tacgactgtt acgttacatt gtccgcctgg tgtggagaat gcattga 597

<210> 1778
<211> 198
<212> PRT
<213> Homo sapien

<400> 1778
 Met Ala Lys Gln Pro Ser Asp Val Ser Ser Glu Cys Asp Arg Glu
   1               5                  10                  15

 Gly Arg Gln Leu Gln Pro Ala Glu Arg Pro Pro Gln Leu Arg Pro
                  20                  25                  30

 Gly Ala Pro Thr Ser Leu Gln Thr Glu Pro Gln Gly Asn Pro Glu
                  35                  40                  45

 Gly Asn His Gly Gly Glu Gly Asp Ser Cys Pro His Gly Ser Pro
                  50                  55                  60

 Gln Gly Pro Leu Ala Pro Pro Ala Ser Pro Gly Pro Phe Ala Thr
                  65                  70                  75

 Arg Ser Pro Leu Phe Ile Phe Met Arg Arg Ser Ser Leu Leu Ser
                  80                  85                  90

 Arg Ser Ser Ser Gly Tyr Phe Ser Phe Asp Thr Asp Arg Ser Pro
                  95                 100                 105

 Ala Pro Met Ser Cys Asp Lys Ser Thr Gln Thr Pro Ser Pro Pro
                 110                 115                 120

 Cys Gln Ala Phe Asn His Tyr Leu Ser Ala Met Ala Ser Met Arg
                 125                 130                 135

 Gln Ala Glu Pro Ala Asp Met Arg Pro Glu Ile Trp Ile Ala Gln
                 140                 145                 150

 Glu Leu Arg Arg Ile Gly Asp Glu Phe Asn Ala Tyr Tyr Ala Arg
                 155                 160                 165

 Arg Val Phe Leu Asn Asn Tyr Gln Ala Ala Glu Asp His Pro Arg
                 170                 175                 180

 Met Val Ile Leu Arg Leu Leu Arg Tyr Ile Val Arg Leu Val Trp
                 185                 190                 195

 Arg Met His


<210> 1779
<211> 257
<212> DNA
<213> Homo sapien

<400> 1779
 accacgcttt tcatctgtcc cgctgcgtgt tttcctcttg atcgggaact 50

 cctgcttctc cttgcctcga aatggacccc aactgctcct gctcgcctgt 100

 tggctcctgt gcctgtgccg gctcctgcaa atgcaaagag tgcaaatgca 150

 cctcctgcaa gaagagctgc tgctcctgct gccctgtcgg ctgtgccaag 200

 tgtgcccagg gctgcatctg caaagggacg tcagacaagt gcagctgctg 250

 tgcctga 257

<210> 1780
<211> 61
<212> PRT
<213> Homo sapien

<400> 1780
 Met Asp Pro Asn Cys Ser Cys Ser Pro Val Gly Ser Cys Ala Cys
   1               5                  10                  15

 Ala Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ala Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Ile Cys Lys Gly Thr Ser Asp Lys Cys Ser Cys Cys
                  50                  55                  60

 Ala


<210> 1781
<211> 2010
<212> DNA
<213> Homo sapien

<400> 1781
 atgtggctct tcttcgggat cactggattg ctgacggcag ccctctcagg 50

 tcatccatct ccagccccac ctgaccagct caacaccagc agtgcagaga 100

 gtgagctctg ggagccaggg gagcggcttc cggtccgtct gacaaacggg 150

 agcagcagct gcagcgggac ggtggaggtg cggctcgagg cgtcctggga 200

 gcccgcgtgc ggggcgctct gggacagccg cgccgccgag gccgtgtgcc 250

 gagcactggg ctgcggcggg gcggaggccg cctctcagct cgccccgccg 300

 acccctgagc tgccgccccc gcctgcagcc gggaacacca gcgtagcagc 350

 taatgccact ctggccgggg cgcccgccct cctgtgcagc ggcgccgagt 400

 ggcggctctg cgaggtggtg gagcacgcgt gccgcagcga cgggaggcgg 450

 gcccgtgtca cctgtgcaga gaaccgcgcg ctgcgcctgg tggacggtgg 500

 cggcgcctgc gccggccgcg tggagatgct ggagcatggc gagtggggat 550

 cagtgtgcga tgacacttgg gacctggagg acgcccacgt ggtgtgcagg 600

 caactgggct gcggctgggc agtccaggcc ctgcccggct tgcacttcac 650

 gcccggccgc gggcctatcc accgggacca ggtgaactgc tcgggggccg 700

 aagcttacct gtgggactgc ccggggctgc caggacagca ctactgcggc 750

 cacaaagagg acgcgggcgt ggtgtgctca gagcaccagt cctggcgcct 800

 gacagggggc gctgaccgct gcgaggggca ggtggaggta cacttccgag 850

 gggtctggaa cacagtgtgt gacagtgagt ggtacccatc ggaggccaag 900

 gtgctctgcc agtccttggg ctgtggaact gcggttgaga ggcccaaggg 950

 gctgccccac tccttgtccg gcaggatgta ctactcatgc aatggggagg 1000

 agctcaccct ctccaactgc tcctggcggt tcaacaactc caacctctgc 1050

 agccagtcgc tggcagccag ggtcctctgc tcagcttccc ggagtttgca 1100

 caatctgtcc actcccgaag tccctgcaag tgttcagaca gtcactatag 1150

 aatcttctgt gacagtgaaa atagagaaca aggaatctcg ggagctaatg 1200

 ctcctcatcc cctccatcgt tctgggaatt ctcctccttg gctccctcat 1250

 cttcatagcc ttcatcctct tgagaattaa aggaaaatat gccctccccg 1300

 taatggtgaa ccaccagcac ctacccacca ccatcccggc agggagcaat 1350

 agctatcaac cggtccccat caccatcccc aaagaagttt tcatgctgcc 1400

 catccaggtc caggccccgc cccctgagga ctcagactct ggctcggact 1450

 cagactatga gcactatgac ttcagcgccc agcctcctgt ggccctgacc 1500

 accttctaca attcccagcg gcatcgggtc acagatgagg aggtccagca 1550

 aagcaggttc cagatgccac ccttggagga aggacttgaa gagttgcatg 1600

 cctcccacat cccaactgcc aaccctggac actgcattac agacccgcca 1650

 tccctgggcc ctcagtatca cccgaggagc aacagtgagt cgagcacctc 1700

 ttcgggggag gattactgca atagtcccaa aagcaagctg cctccatgga 1750

 acccccaggt gttttcttca gagaggagtt ccttcctgga gcagccccca 1800

 aacttggagc tggccggcac ccagccagcc ttttcagcag ggcccccggc 1850

 tgatgacagc tccagcacct catccgggga gtggtaccag aacttccagc 1900

 caccacccca gcccccttcg gaggagcagt ttggctgtcc agggtccccc 1950

 agccctcagc ctgactccac cgacaacgat gactacgatg acatcagcgc 2000

 agcctaggcc 2010

<210> 1782
<211> 668
<212> PRT
<213> Homo sapien

<400> 1782
 Met Trp Leu Phe Phe Gly Ile Thr Gly Leu Leu Thr Ala Ala Leu
   1               5                  10                  15

 Ser Gly His Pro Ser Pro Ala Pro Pro Asp Gln Leu Asn Thr Ser
                  20                  25                  30

 Ser Ala Glu Ser Glu Leu Trp Glu Pro Gly Glu Arg Leu Pro Val
                  35                  40                  45

 Arg Leu Thr Asn Gly Ser Ser Ser Cys Ser Gly Thr Val Glu Val
                  50                  55                  60

 Arg Leu Glu Ala Ser Trp Glu Pro Ala Cys Gly Ala Leu Trp Asp
                  65                  70                  75

 Ser Arg Ala Ala Glu Ala Val Cys Arg Ala Leu Gly Cys Gly Gly
                  80                  85                  90

 Ala Glu Ala Ala Ser Gln Leu Ala Pro Pro Thr Pro Glu Leu Pro
                  95                 100                 105

 Pro Pro Pro Ala Ala Gly Asn Thr Ser Val Ala Ala Asn Ala Thr
                 110                 115                 120

 Leu Ala Gly Ala Pro Ala Leu Leu Cys Ser Gly Ala Glu Trp Arg
                 125                 130                 135

 Leu Cys Glu Val Val Glu His Ala Cys Arg Ser Asp Gly Arg Arg
                 140                 145                 150

 Ala Arg Val Thr Cys Ala Glu Asn Arg Ala Leu Arg Leu Val Asp
                 155                 160                 165

 Gly Gly Gly Ala Cys Ala Gly Arg Val Glu Met Leu Glu His Gly
                 170                 175                 180

 Glu Trp Gly Ser Val Cys Asp Asp Thr Trp Asp Leu Glu Asp Ala
                 185                 190                 195

 His Val Val Cys Arg Gln Leu Gly Cys Gly Trp Ala Val Gln Ala
                 200                 205                 210

 Leu Pro Gly Leu His Phe Thr Pro Gly Arg Gly Pro Ile His Arg
                 215                 220                 225

 Asp Gln Val Asn Cys Ser Gly Ala Glu Ala Tyr Leu Trp Asp Cys
                 230                 235                 240

 Pro Gly Leu Pro Gly Gln His Tyr Cys Gly His Lys Glu Asp Ala
                 245                 250                 255

 Gly Val Val Cys Ser Glu His Gln Ser Trp Arg Leu Thr Gly Gly
                 260                 265                 270

 Ala Asp Arg Cys Glu Gly Gln Val Glu Val His Phe Arg Gly Val
                 275                 280                 285

 Trp Asn Thr Val Cys Asp Ser Glu Trp Tyr Pro Ser Glu Ala Lys
                 290                 295                 300

 Val Leu Cys Gln Ser Leu Gly Cys Gly Thr Ala Val Glu Arg Pro
                 305                 310                 315

 Lys Gly Leu Pro His Ser Leu Ser Gly Arg Met Tyr Tyr Ser Cys
                 320                 325                 330

 Asn Gly Glu Glu Leu Thr Leu Ser Asn Cys Ser Trp Arg Phe Asn
                 335                 340                 345

 Asn Ser Asn Leu Cys Ser Gln Ser Leu Ala Ala Arg Val Leu Cys
                 350                 355                 360

 Ser Ala Ser Arg Ser Leu His Asn Leu Ser Thr Pro Glu Val Pro
                 365                 370                 375

 Ala Ser Val Gln Thr Val Thr Ile Glu Ser Ser Val Thr Val Lys
                 380                 385                 390

 Ile Glu Asn Lys Glu Ser Arg Glu Leu Met Leu Leu Ile Pro Ser
                 395                 400                 405

 Ile Val Leu Gly Ile Leu Leu Leu Gly Ser Leu Ile Phe Ile Ala
                 410                 415                 420

 Phe Ile Leu Leu Arg Ile Lys Gly Lys Tyr Ala Leu Pro Val Met
                 425                 430                 435

 Val Asn His Gln His Leu Pro Thr Thr Ile Pro Ala Gly Ser Asn
                 440                 445                 450

 Ser Tyr Gln Pro Val Pro Ile Thr Ile Pro Lys Glu Val Phe Met
                 455                 460                 465

 Leu Pro Ile Gln Val Gln Ala Pro Pro Pro Glu Asp Ser Asp Ser
                 470                 475                 480

 Gly Ser Asp Ser Asp Tyr Glu His Tyr Asp Phe Ser Ala Gln Pro
                 485                 490                 495

 Pro Val Ala Leu Thr Thr Phe Tyr Asn Ser Gln Arg His Arg Val
                 500                 505                 510

 Thr Asp Glu Glu Val Gln Gln Ser Arg Phe Gln Met Pro Pro Leu
                 515                 520                 525

 Glu Glu Gly Leu Glu Glu Leu His Ala Ser His Ile Pro Thr Ala
                 530                 535                 540

 Asn Pro Gly His Cys Ile Thr Asp Pro Pro Ser Leu Gly Pro Gln
                 545                 550                 555

 Tyr His Pro Arg Ser Asn Ser Glu Ser Ser Thr Ser Ser Gly Glu
                 560                 565                 570

 Asp Tyr Cys Asn Ser Pro Lys Ser Lys Leu Pro Pro Trp Asn Pro
                 575                 580                 585

 Gln Val Phe Ser Ser Glu Arg Ser Ser Phe Leu Glu Gln Pro Pro
                 590                 595                 600

 Asn Leu Glu Leu Ala Gly Thr Gln Pro Ala Phe Ser Ala Gly Pro
                 605                 610                 615

 Pro Ala Asp Asp Ser Ser Ser Thr Ser Ser Gly Glu Trp Tyr Gln
                 620                 625                 630

 Asn Phe Gln Pro Pro Pro Gln Pro Pro Ser Glu Glu Gln Phe Gly
                 635                 640                 645

 Cys Pro Gly Ser Pro Ser Pro Gln Pro Asp Ser Thr Asp Asn Asp
                 650                 655                 660

 Asp Tyr Asp Asp Ile Ser Ala Ala
                 665

<210> 1783
<211> 2978
<212> DNA
<213> Homo sapien

<400> 1783
 aagggaagtc ggctcaggag gaccgagtga gggcaccgag gcgggacgca 50

 cgcacccggc gaaggttgct ccaccccggt caggatcagg cgagggggaa 100

 ccagcctgag tgcagctgcc aactcccgcc gagtgcgtct gcgaactccc 150

 ggagcggagt cccgcgtgcc gccacctccc cgcggacgca ctctcctcgc 200

 tcccccgggc cccgcgtcct ccccccggcc acccttcccc acttttcccc 250

 ccttttccaa tcacatggca ttttaagaat gccggaaaga tggcggtagc 300

 ggcggcggcg gcggcggctg ggccggctgg cgcgggaggc ggccgggcgc 350

 agcggagcgg gctgctggaa gttttggtgc gggatcgctg gcacaaagtt 400

 ctggtgaact tgagcgagga cgccctggtt ctgagcagcg aggagggcgc 450

 tgcggcgtac aacggcatcg ggaccgccac caatggctcg ttctgcaggg 500

 gcgccggggc tgggcacccg ggcgcgggcg gcgcgcagcc cccggactcg 550

 cccgccgggg tccgcaccgc tttcaccgac ctgcccgagc aggtgcccga 600

 gtccatctcg aaccagaagc gtggcgtgaa ggtgctgaag caggagctgg 650

 gcgggctggg gatcagcatc aaggggggca aggagaacaa gatgcccatc 700

 ctcatcagca agatcttcaa ggggctggcg gcggaccaga cccaagccct 750

 gtacgtgggc gacgccatcc tgtccgtgaa cggagccgac ctgcgggacg 800

 ccacccacga cgaggcggtg caggcgttga agcgcgcggg caaggaagtg 850

 ctgctggaag tgaagtacat gcgagaagcc acgccctatg tgaagaaagg 900

 atccccagta tccgagattg ggtgggaaac acctccgcct gaatcccctc 950

 ggttaggggg cagcacctca gaccccccgt catcgcagtc cttctccttc 1000

 cacagagacc ggaaaagcat ccccctcaaa atgtgctacg tcactcggag 1050

 tatggccttg gccgaccctg agaacaggca gcttgaaatc cactctccag 1100

 atgctaagca cacggtgatc ctaaggagca aggactcagc cacggcccag 1150

 gcatggttca gtgccatcca ttccaacgtt aatgacctgc tgacccgagt 1200

 gattgctgag gtcagagagc agctggggaa aacaggcatt gctgggagcc 1250

 gagagattag gcatcttggc tggcttgcag aaaaggtgcc aggggagagc 1300

 aagaaacagt ggaaaccagc cctggttgtg ctgactgaga aagacctttt 1350

 aatctatgac agcatgccac ggaggaagga agcctggttc agcccagttc 1400

 acacataccc tcttcttgcc accaggctgg tccattcagg tccaggaaag 1450

 ggatcacccc aggctggtgt ggatctgtcc tttgcaacgc gaactggtac 1500

 caggcaaggg attgaaacac atctcttcag agcagagacc agcagggacc 1550

 tctcccactg gacaaggagc atagtacagg gttgccacaa ttctgctgaa 1600

 ctcattgctg aaatcagcac tgcttgcacc tacaaaaacc aggagtgccg 1650

 tttgaccata cattatgaga atggattttc tattaccact gaaccacagg 1700

 agggtgcctt tcccaagacc atcatacagt ctccttatga aaagctcaaa 1750

 atgtcttcag atgatggaat caggatgctg tatttagatt ttggaggcaa 1800

 agatggagag attcaactgg accttcattc ctgccccaag ccaattgttt 1850

 tcatcattca ttccttcctg tcagctaaga ttacaagact gggcttggtg 1900

 gcctgaagac aggggtgact tgcctttgag aaaagaaggg ctgcaatgcc 1950

 accagagaac gtgatgtcag acaccatctg tagtgagcag cgcaccagat 2000

 gtagcgtgct acagtcagct ttagctctca agagtcgtat gtaactgtcc 2050

 cagactcctc tgtcagtttc agcaactaca agggataccc tgcgaaagta 2100

 ccatgagaaa tatcagagta aaactttcta gaacagtaca aggttaaaga 2150

 ggtgaggtga cgggaaatac acagcatagc tttgaaataa tgacaaccaa 2200

 ggacatgacc attagaacag catgtgcaga tcttaatcat cccagttcct 2250

 aggcaacttg ttcaccaggt acgcaagggc cgaatagttg agaaatggac 2300

 atttttacct actcctccta gccccctatc cccagtaaca gtgatccctt 2350

 ttcttattgt gatttatttc ctaattcttg ctgagttgac tttcccttgt 2400

 aggaaaagaa aaatatttca aatagaaacc caccttttat ttaagtatga 2450

 agcagctgtt actttttaaa aaatgaatta tctttcaatg gtgtagaatg 2500

 attccaaagt gtctccatta gcatatactg agcaggaatt aaataaagca 2550

 tcagatactg atctgagctg taagctggta gaatctgagc caaagtagac 2600

 tgcttaaatt gataagcttt gctaaagagt tgtatgcaca aaggatgatt 2650

 aattctggga ctatactcac accaaggtct gctgtcttat agccaagaat 2700

 tacagcttta tttatagaga gtgaattatg ggtatttttt cagaaaatat 2750

 tgtcatctga tatacacata aaacaactca cattgttgga gttaactaat 2800

 tatccccatt tcatggtttt cagtggcaac ttactgaccc ttgtttttgc 2850

 ctgtgcttgt atgcatgcat tttcaagcaa gtaataaagc agcctcattt 2900

 aattctggat aatgctgggt tttacatata gactgaatgc tataatcaaa 2950

 tctattgaca gtatctgcag ttctttca 2978

<210> 1784
<211> 538
<212> PRT
<213> Homo sapien

<400> 1784
 Met Ala Val Ala Ala Ala Ala Ala Ala Ala Gly Pro Ala Gly Ala
   1               5                  10                  15

 Gly Gly Gly Arg Ala Gln Arg Ser Gly Leu Leu Glu Val Leu Val
                  20                  25                  30

 Arg Asp Arg Trp His Lys Val Leu Val Asn Leu Ser Glu Asp Ala
                  35                  40                  45

 Leu Val Leu Ser Ser Glu Glu Gly Ala Ala Ala Tyr Asn Gly Ile
                  50                  55                  60

 Gly Thr Ala Thr Asn Gly Ser Phe Cys Arg Gly Ala Gly Ala Gly
                  65                  70                  75

 His Pro Gly Ala Gly Gly Ala Gln Pro Pro Asp Ser Pro Ala Gly
                  80                  85                  90

 Val Arg Thr Ala Phe Thr Asp Leu Pro Glu Gln Val Pro Glu Ser
                  95                 100                 105

 Ile Ser Asn Gln Lys Arg Gly Val Lys Val Leu Lys Gln Glu Leu
                 110                 115                 120

 Gly Gly Leu Gly Ile Ser Ile Lys Gly Gly Lys Glu Asn Lys Met
                 125                 130                 135

 Pro Ile Leu Ile Ser Lys Ile Phe Lys Gly Leu Ala Ala Asp Gln
                 140                 145                 150

 Thr Gln Ala Leu Tyr Val Gly Asp Ala Ile Leu Ser Val Asn Gly
                 155                 160                 165

 Ala Asp Leu Arg Asp Ala Thr His Asp Glu Ala Val Gln Ala Leu
                 170                 175                 180

 Lys Arg Ala Gly Lys Glu Val Leu Leu Glu Val Lys Tyr Met Arg
                 185                 190                 195

 Glu Ala Thr Pro Tyr Val Lys Lys Gly Ser Pro Val Ser Glu Ile
                 200                 205                 210

 Gly Trp Glu Thr Pro Pro Pro Glu Ser Pro Arg Leu Gly Gly Ser
                 215                 220                 225

 Thr Ser Asp Pro Pro Ser Ser Gln Ser Phe Ser Phe His Arg Asp
                 230                 235                 240

 Arg Lys Ser Ile Pro Leu Lys Met Cys Tyr Val Thr Arg Ser Met
                 245                 250                 255

 Ala Leu Ala Asp Pro Glu Asn Arg Gln Leu Glu Ile His Ser Pro
                 260                 265                 270

 Asp Ala Lys His Thr Val Ile Leu Arg Ser Lys Asp Ser Ala Thr
                 275                 280                 285

 Ala Gln Ala Trp Phe Ser Ala Ile His Ser Asn Val Asn Asp Leu
                 290                 295                 300

 Leu Thr Arg Val Ile Ala Glu Val Arg Glu Gln Leu Gly Lys Thr
                 305                 310                 315

 Gly Ile Ala Gly Ser Arg Glu Ile Arg His Leu Gly Trp Leu Ala
                 320                 325                 330

 Glu Lys Val Pro Gly Glu Ser Lys Lys Gln Trp Lys Pro Ala Leu
                 335                 340                 345

 Val Val Leu Thr Glu Lys Asp Leu Leu Ile Tyr Asp Ser Met Pro
                 350                 355                 360

 Arg Arg Lys Glu Ala Trp Phe Ser Pro Val His Thr Tyr Pro Leu
                 365                 370                 375

 Leu Ala Thr Arg Leu Val His Ser Gly Pro Gly Lys Gly Ser Pro
                 380                 385                 390

 Gln Ala Gly Val Asp Leu Ser Phe Ala Thr Arg Thr Gly Thr Arg
                 395                 400                 405

 Gln Gly Ile Glu Thr His Leu Phe Arg Ala Glu Thr Ser Arg Asp
                 410                 415                 420

 Leu Ser His Trp Thr Arg Ser Ile Val Gln Gly Cys His Asn Ser
                 425                 430                 435

 Ala Glu Leu Ile Ala Glu Ile Ser Thr Ala Cys Thr Tyr Lys Asn
                 440                 445                 450

 Gln Glu Cys Arg Leu Thr Ile His Tyr Glu Asn Gly Phe Ser Ile
                 455                 460                 465

 Thr Thr Glu Pro Gln Glu Gly Ala Phe Pro Lys Thr Ile Ile Gln
                 470                 475                 480

 Ser Pro Tyr Glu Lys Leu Lys Met Ser Ser Asp Asp Gly Ile Arg
                 485                 490                 495

 Met Leu Tyr Leu Asp Phe Gly Gly Lys Asp Gly Glu Ile Gln Leu
                 500                 505                 510

 Asp Leu His Ser Cys Pro Lys Pro Ile Val Phe Ile Ile His Ser
                 515                 520                 525

 Phe Leu Ser Ala Lys Ile Thr Arg Leu Gly Leu Val Ala
                 530                 535

<210> 1785
<211> 1474
<212> DNA
<213> Homo sapien

<400> 1785
 aaaaagaaat caagaatgca attttattta caatagtcac gccggaaata 50

 cctagaaata aatttaactg aggatgtaaa agacctctac aaggagagtt 100

 caatgcgtag cgggagcgga gagctgaccc cagagagccc tgggcagccc 150

 cacctccgcc gccggcctag ttaccatcac accccggaga gcccgcagct 200

 gccgcagccg gccccagtca ccatcaccgc aaccatgagc agcgaggccg 250

 agacccagca gccgcccgcc gccccccccg ccgcccccgc cctcagcgcc 300

 gccgacacca agcccggcac taccggagcg gcgcagggag cggtggcccg 350

 ggcggctcac atcggcggcg ctggcgcggg cgacaagaag gtcatcgcaa 400

 cgaaggtttt gggaacagta aaatggttca atgtaaggaa cggatatggt 450

 ttcatcaaca ggaatgacac caaggaagat gtatttgtac accagactgc 500

 cataaagaag aataacccca ggaagtacct tcgcagtgta ggagatggag 550

 agactgtgga gtttgatgtt gttgaaggag aaaagggtgc ggaggcagca 600

 aatgttacag gtcctggtgg tgttccagtt caaggcagta aatatgcagc 650

 agaccgtaac cattatagac gctatccacg tcgtaggggt cctccacgca 700

 attaccagca aaattaccag aatagtgaga gtggggaaaa gaacgaggga 750

 tcggagagtg ctcccgaagc caggcccaac aacgccggcc ctacgcaggc 800

 gaaggttccc accttactac atgcggagac ctatgggcgt cgaccacagt 850

 attccaaccc tcctgtgcag ggagaagtga tggagggtgc tgacaaccag 900

 ggtgcaggag aacaaggtag accagtgagg cagatatgta tcggggatat 950

 agaccacgat tccgcagggg ccctcctcgc caaaagacag cctagagagg 1000

 acggcaatga agaagataaa gaaaatcaag gagatgagac ccaaggtcag 1050

 cagccacctc aagctcggta ccgccgcaac ttcaattacc gacgcagacg 1100

 cccagaaaac cctaaaccac aagatggcaa agagacaaaa gcagccgatc 1150

 caccagctga gaattcgtcc gctcccgagg ctgagcaggg cggggctgag 1200

 taaatgccgg cttaccatct ctaccatcat ccggtttagt catccaacaa 1250

 gaagaaatat gaaattccag caataagaaa tgaacaaaag attggagctg 1300

 aagacctaaa gtgcttgctt tttgcccgtt gaccagataa atagaactat 1350

 ctgcattatc tatgcagcat ggggttttta ttatgtttta cctaaagacg 1400

 tctctttttg gtaataacaa accgtgtttt ttaaaaaagc ctggtttttc 1450

 tcaatacgcc tttaaaggaa ttcc 1474

<210> 1786
<211> 322
<212> PRT
<213> Homo sapien

<400> 1786
 Met Ser Ser Glu Ala Glu Thr Gln Gln Pro Pro Ala Ala Pro Pro
   1               5                  10                  15

 Ala Ala Pro Ala Leu Ser Ala Ala Asp Thr Lys Pro Gly Thr Thr
                  20                  25                  30

 Gly Ala Ala Gln Gly Ala Val Ala Arg Ala Ala His Ile Gly Gly
                  35                  40                  45

 Ala Gly Ala Gly Asp Lys Lys Val Ile Ala Thr Lys Val Leu Gly
                  50                  55                  60

 Thr Val Lys Trp Phe Asn Val Arg Asn Gly Tyr Gly Phe Ile Asn
                  65                  70                  75

 Arg Asn Asp Thr Lys Glu Asp Val Phe Val His Gln Thr Ala Ile
                  80                  85                  90

 Lys Lys Asn Asn Pro Arg Lys Tyr Leu Arg Ser Val Gly Asp Gly
                  95                 100                 105

 Glu Thr Val Glu Phe Asp Val Val Glu Gly Glu Lys Gly Ala Glu
                 110                 115                 120

 Ala Ala Asn Val Thr Gly Pro Gly Gly Val Pro Val Gln Gly Ser
                 125                 130                 135

 Lys Tyr Ala Ala Asp Arg Asn His Tyr Arg Arg Tyr Pro Arg Arg
                 140                 145                 150

 Arg Gly Pro Pro Arg Asn Tyr Gln Gln Asn Tyr Gln Asn Ser Glu
                 155                 160                 165

 Ser Gly Glu Lys Asn Glu Gly Ser Glu Ser Ala Pro Glu Ala Arg
                 170                 175                 180

 Pro Asn Asn Ala Gly Pro Thr Gln Ala Lys Val Pro Thr Leu Leu
                 185                 190                 195

 His Ala Glu Thr Tyr Gly Arg Arg Pro Gln Tyr Ser Asn Pro Pro
                 200                 205                 210

 Val Gln Gly Glu Val Met Glu Gly Ala Asp Asn Gln Gly Ala Gly
                 215                 220                 225

 Glu Gln Gly Arg Pro Val Arg Gln Ile Cys Ile Gly Asp Ile Asp
                 230                 235                 240

 His Asp Ser Ala Gly Ala Leu Leu Ala Lys Arg Gln Pro Arg Glu
                 245                 250                 255

 Asp Gly Asn Glu Glu Asp Lys Glu Asn Gln Gly Asp Glu Thr Gln
                 260                 265                 270

 Gly Gln Gln Pro Pro Gln Ala Arg Tyr Arg Arg Asn Phe Asn Tyr
                 275                 280                 285

 Arg Arg Arg Arg Pro Glu Asn Pro Lys Pro Gln Asp Gly Lys Glu
                 290                 295                 300

 Thr Lys Ala Ala Asp Pro Pro Ala Glu Asn Ser Ser Ala Pro Glu
                 305                 310                 315

 Ala Glu Gln Gly Gly Ala Glu
                 320

<210> 1787
<211> 589
<212> DNA
<213> Homo sapien

<400> 1787
 ctccgccctc tcccactctc tctttccggt gtggagtctg gagacgacgt 50

 gcagaaatgg cacctcgaaa ggggaaggaa aagaaggaag aacaggtcat 100

 cagcctcgga cctcaggtgg ctgaaggaga gaatgtattt ggtgtctgcc 150

 atatctttgc atccttcaat gacacttttg tccatgtcac tgatctttct 200

 ggcaaggaaa ccatctgccg tgtgactggt gggatgaagg taaaggcaga 250

 ccgagatgaa tcctcaccat atgctgctat gttggctgcc caggatgtgg 300

 cccagaggtg caaggagctg ggtatcaccg ccctacacat caaactccgg 350

 gccacaggag gaaataggac caagacccct ggacctgggg cccagtcggc 400

 cctcagagcc cttgcccgct cgggtatgaa gatcgggcgg attgaggatg 450

 tcacccccat cccctctgac agcactcgca ggaagggggg tcgccgtggt 500

 cgccgtctgt gaacaagatt cctcaaaata ttttctgtta ataaattgcc 550

 ttcatgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 589

<210> 1788
<211> 151
<212> PRT
<213> Homo sapien

<400> 1788
 Met Ala Pro Arg Lys Gly Lys Glu Lys Lys Glu Glu Gln Val Ile
   1               5                  10                  15

 Ser Leu Gly Pro Gln Val Ala Glu Gly Glu Asn Val Phe Gly Val
                  20                  25                  30

 Cys His Ile Phe Ala Ser Phe Asn Asp Thr Phe Val His Val Thr
                  35                  40                  45

 Asp Leu Ser Gly Lys Glu Thr Ile Cys Arg Val Thr Gly Gly Met
                  50                  55                  60

 Lys Val Lys Ala Asp Arg Asp Glu Ser Ser Pro Tyr Ala Ala Met
                  65                  70                  75

 Leu Ala Ala Gln Asp Val Ala Gln Arg Cys Lys Glu Leu Gly Ile
                  80                  85                  90

 Thr Ala Leu His Ile Lys Leu Arg Ala Thr Gly Gly Asn Arg Thr
                  95                 100                 105

 Lys Thr Pro Gly Pro Gly Ala Gln Ser Ala Leu Arg Ala Leu Ala
                 110                 115                 120

 Arg Ser Gly Met Lys Ile Gly Arg Ile Glu Asp Val Thr Pro Ile
                 125                 130                 135

 Pro Ser Asp Ser Thr Arg Arg Lys Gly Gly Arg Arg Gly Arg Arg
                 140                 145                 150

 Leu


<210> 1789
<211> 3038
<212> DNA
<213> Homo sapien

<400> 1789
 cggacgcgtg ggtcgaccca cgcgtccgga ttgaggggtt gactgagcgt 50

 tgcgagcctt agctttctcc cgaacgccag cgctgaggac acgatgtcgc 100

 ggctctcccg ctcactgctt tgggccgcca cctgcctggg cgtgctctgc 150

 gtgctgtccg cggacaagaa cacgacccag cacccgaacg tgacgacttt 200

 agcgcccatc tccaacgtaa cctcggcgcc ggtgacgtcc ctcccgctgg 250

 tcaccactcc ggcaccagaa acctgtgaag gtcgaaacag ctgcgtttcc 300

 tgttttaatg ttagcgttgt taatactacc tgcttttgga tagaatgtaa 350

 agatgagagc tattgttcac ataactcaac agttagtgat tgtcaagtgg 400

 ggaacacgac agacttctgt tccgtttcca cggccactcc agtgccaaca 450

 gccaattcta cagctaaacc cacagttcag ccctcccctt ctacaacttc 500

 caagacagtt actacatcag gtacaacaaa taacactgtg actccaacct 550

 cacaacctgt gcgaaagtct acctttgatg cagccagttt cattggagga 600

 attgtcctgg tcttgggtgt gcaggctgta attttctttc tttataaatt 650

 ctgcaaatct aaagaacgaa attaccacac tctgtaaaca gacccattga 700

 attaataagg actggtgatt catttgtgta actcactgaa gccaaaatac 750

 tatcttttaa gatgtcccac atggaagacg ctattccagg atctttaaat 800

 ttccatggat gcatatagga tgtttgggag catcatccgt gaagaaaaaa 850

 tcaattaaat cattgtgttc aacaggaata tttaaaatat tctgcatgaa 900

 tcctgtggct gtcttatttt aaatagctgc tgctgtggga ttatattttt 950

 tttccttaac atgccaaata taactttctg aaagtgatgg aaaatgttgt 1000

 cttgtgcaga caacatcatg gctcttggca gtttaaattt agtaatttta 1050

 atttagtgaa cagaattgag aagaacgtgc caaatgagaa tcaattaggt 1100

 ggatttttgg ctgtcatttc aaaagtggaa taaatttatt aatttagtag 1150

 tactaaatgg tatccttaga ttaaaatttt gtgcttgata acagctgttt 1200

 tttctacatt agaaataaga tgccacacaa ggaactacat tccagattta 1250

 aagaaatgaa aggataccat tagtgtgtat aacagattat tgttcatact 1300

 tgtaaagcat cttatgtcat tgagaatata aagaacagtg ccttagaaga 1350

 cagtgaaagg taagctctag cttaatgtct atgatttgtt ctttgacatt 1400

 aaggaaggta aggattggtc agaggatgta acttgatgtg agcagtagta 1450

 aacctgtttt agatatcata ctgttaatat tttattgaaa atttatttca 1500

 gagcggagaa acttaagcta aagtctgtta tacagaattg aaagccttcg 1550

 tatcttgaac ctcccaacat ttttcttatg gctgttgaaa agtatagagc 1600

 taaattgatt taattacact ttcctttgta ctttaaaaaa aagtatgcta 1650

 gcactattgt accttgaaag gatttccacc agactgtctt gagtagtgac 1700

 ttctttggtg aggcaagaag gatatacatt attttagaat catttactat 1750

 ttaaatgaga caatcatatt attttagaat catttatttt aaatgagaca 1800

 atcattttaa gttttaagat aacagaagtg accaatgtaa tttcacaaca 1850

 cctaaggatt ttttggttga tcaggttact gtagattttt actgattgtc 1900

 ctggatgaat agactgtgct ttttcttttt ctctcccttc cttcttggtt 1950

 tcccatagta taataagcat gcatacttta acttctatag ttttctcctt 2000

 tagagggtcg tcttcagttt tagaggttta cttctccctt gcctttgact 2050

 cattggacta gtgcagaggc tttaagtagt ttaaaatggg cttttgcttt 2100

 tctaggtcat taacgttttt tatttagttt ctttagccaa tagtggctga 2150

 gtttcgcact tgattttcaa tattttatag taagaaatga caaactgctt 2200

 tgtttcattt cataaacaaa ctctgcattt agataactat taaaggttgt 2250

 taagatgaag atttactgtt tctttgttac tcgttggtac agctgtttgt 2300

 tttacttgca catttgtaca tatacttaat gttttcaagt gccttaattg 2350

 tttaaaatct ctggcttcaa agtttcttgg ggaaaggtcg gtttacctca 2400

 cattttttgt ttccattagt aatattctag gtacctcaca aaatgtatta 2450

 tggtgccatg gctgttagtt tttagtgagt gctgtaggat taattcgaaa 2500

 ataggcagaa ttccattcct cccaaggtgg caaaaattag ctatactgat 2550

 gtaattgtca tttacctggg tatgaattcc ctgacacaca ttcatgtcaa 2600

 catatgtagc aaattttgtg aaaacataac aatttgaagc ttctgtaatt 2650

 ttgagcactg ctctaacaac aagcataata taaaattagt tagattttgc 2700

 aagtctacaa atgagctctt gcaacagaac tcacagcctt tttacttttt 2750

 tcccctaact ttagcaatgt agtatcttga gccattaatt tttgggtttt 2800

 tttaaaatcc agaaggtata tagaaacctt ttcagatttt tcatctgatt 2850

 tgttcttgca gatgttcttc tatcaaatac cttattttac cttacagata 2900

 tttgttgcac aggcagatac tgctgtattt agacatttct atttcagttc 2950

 attaaaaact gcaaaaccaa tctgtatcat gtaccaaact gacttaaaat 3000

 aaatctacat gtttattgaa aaaaaaaaaa aaaaaaaa 3038

<210> 1790
<211> 197
<212> PRT
<213> Homo sapien

<400> 1790
 Met Ser Arg Leu Ser Arg Ser Leu Leu Trp Ala Ala Thr Cys Leu
   1               5                  10                  15

 Gly Val Leu Cys Val Leu Ser Ala Asp Lys Asn Thr Thr Gln His
                  20                  25                  30

 Pro Asn Val Thr Thr Leu Ala Pro Ile Ser Asn Val Thr Ser Ala
                  35                  40                  45

 Pro Val Thr Ser Leu Pro Leu Val Thr Thr Pro Ala Pro Glu Thr
                  50                  55                  60

 Cys Glu Gly Arg Asn Ser Cys Val Ser Cys Phe Asn Val Ser Val
                  65                  70                  75

 Val Asn Thr Thr Cys Phe Trp Ile Glu Cys Lys Asp Glu Ser Tyr
                  80                  85                  90

 Cys Ser His Asn Ser Thr Val Ser Asp Cys Gln Val Gly Asn Thr
                  95                 100                 105

 Thr Asp Phe Cys Ser Val Ser Thr Ala Thr Pro Val Pro Thr Ala
                 110                 115                 120

 Asn Ser Thr Ala Lys Pro Thr Val Gln Pro Ser Pro Ser Thr Thr
                 125                 130                 135

 Ser Lys Thr Val Thr Thr Ser Gly Thr Thr Asn Asn Thr Val Thr
                 140                 145                 150

 Pro Thr Ser Gln Pro Val Arg Lys Ser Thr Phe Asp Ala Ala Ser
                 155                 160                 165

 Phe Ile Gly Gly Ile Val Leu Val Leu Gly Val Gln Ala Val Ile
                 170                 175                 180

 Phe Phe Leu Tyr Lys Phe Cys Lys Ser Lys Glu Arg Asn Tyr His
                 185                 190                 195

 Thr Leu


<210> 1791
<211> 1648
<212> DNA
<213> Homo sapien

<400> 1791
 ggcacgagtg cgcctcagcc cgcgcgctcg cagcttctcg ctctcgcctg 50

 cctgcccgct cccttgcttg ctcgcgcttt cgctcgccct ctcctcgagg 100

 atcgagggga ctctgaccac agcctgtggc tgggaaggga gacagaggcg 150

 gcggcggctc aggggaaacg aggctgcagt ggtggtagta ggaagatgtc 200

 gggcgaggac gagcaacagg agcaaactat cgctgaggac ctggtcgtga 250

 ccaagtataa gatggggggc gacatcgcca acagggtact tcggtccttg 300

 gtggaagcat ctagctcagg tgtgtcggta ctgagcctgt gtgagaaagg 350

 tgatgccatg attatggaag aaacagggaa aatcttcaag aaagaaaagg 400

 aaatgaagaa aggtattgct tttcccacca gcatttcggt aaataactgt 450

 gtatgtcact tctccccttt gaagagcgac caggattata ttctcaagga 500

 aggtgacttg gtaaaaattg accttggggt ccatgtggat ggcttcatcg 550

 ctaatgtagc tcacactttt gtggttgatg tagctcaggg gacccaagta 600

 acagggagga aagcagatgt tattaaggca gctcaccttt gtgctgaagc 650

 tgccctacgc ctggtcaaac ctggaaatca gaacacacaa gtgacagaag 700

 cctggaacaa agttgcccac tcatttaact gcacgccaat agaaggtatg 750

 ctgtcacacc agttgaagca gcatgtcatc gatggagaaa aaaccattat 800

 ccagaatccc acagaccagc agaagaagga ccatgaaaaa gctgaatttg 850

 aggtacatga agtatatgct gtggatgttc tcgtcagctc aggagagggc 900

 aaggccaagg atgcaggaca gagaaccact atttacaaac gagacccctc 950

 taaacagtat ggactgaaaa tgaaaacttc acgtgccttc ttcagtgagg 1000

 tggaaaggcg ttttgatgcc atgccgttta ctttaagagc atttgaagat 1050

 gagaagaagg ctcggatggg tgtggtggag tgcgccaaac atgaactgct 1100

 gcaaccattt aatgttctct atgagaagga gggtgaattt gttgcccagt 1150

 ttaaatttac agttctgctc atgcccaatg gccccatgcg gataaccagt 1200

 ggtcccttcg agcctgacct ctacaagtct gagatggagg tccaggatgc 1250

 agagctaaag gccctcctcc agagttctgc aagtcgaaaa acccagaaaa 1300

 agaagaaaaa gaaggcctcc aagactgcag agaatgccac cagtggggaa 1350

 acattagaag aaaatgaagc tggggactga ggtgggtccc atctccccag 1400

 cttgctgctc ctgccctcat ccccttccca ccaaacccca gactctgtga 1450

 agtgcagttc ttctccacct aggaccgcca gcagagcggg gggatttccc 1500

 tgcccccacc ccagttcccc aacccactcc cttccaacaa caaccagctc 1550

 caactgaatt tggttttggg aggtgaggct tcccaaccac ggaagactac 1600

 tttaaatgaa aaaaagaaat tgaataataa aatcaggagt taaaattc 1648

<210> 1792
<211> 340
<212> PRT
<213> Homo sapien

<400> 1792
 Met Ile Met Glu Glu Thr Gly Lys Ile Phe Lys Lys Glu Lys Glu
   1               5                  10                  15

 Met Lys Lys Gly Ile Ala Phe Pro Thr Ser Ile Ser Val Asn Asn
                  20                  25                  30

 Cys Val Cys His Phe Ser Pro Leu Lys Ser Asp Gln Asp Tyr Ile
                  35                  40                  45

 Leu Lys Glu Gly Asp Leu Val Lys Ile Asp Leu Gly Val His Val
                  50                  55                  60

 Asp Gly Phe Ile Ala Asn Val Ala His Thr Phe Val Val Asp Val
                  65                  70                  75

 Ala Gln Gly Thr Gln Val Thr Gly Arg Lys Ala Asp Val Ile Lys
                  80                  85                  90

 Ala Ala His Leu Cys Ala Glu Ala Ala Leu Arg Leu Val Lys Pro
                  95                 100                 105

 Gly Asn Gln Asn Thr Gln Val Thr Glu Ala Trp Asn Lys Val Ala
                 110                 115                 120

 His Ser Phe Asn Cys Thr Pro Ile Glu Gly Met Leu Ser His Gln
                 125                 130                 135

 Leu Lys Gln His Val Ile Asp Gly Glu Lys Thr Ile Ile Gln Asn
                 140                 145                 150

 Pro Thr Asp Gln Gln Lys Lys Asp His Glu Lys Ala Glu Phe Glu
                 155                 160                 165

 Val His Glu Val Tyr Ala Val Asp Val Leu Val Ser Ser Gly Glu
                 170                 175                 180

 Gly Lys Ala Lys Asp Ala Gly Gln Arg Thr Thr Ile Tyr Lys Arg
                 185                 190                 195

 Asp Pro Ser Lys Gln Tyr Gly Leu Lys Met Lys Thr Ser Arg Ala
                 200                 205                 210

 Phe Phe Ser Glu Val Glu Arg Arg Phe Asp Ala Met Pro Phe Thr
                 215                 220                 225

 Leu Arg Ala Phe Glu Asp Glu Lys Lys Ala Arg Met Gly Val Val
                 230                 235                 240

 Glu Cys Ala Lys His Glu Leu Leu Gln Pro Phe Asn Val Leu Tyr
                 245                 250                 255

 Glu Lys Glu Gly Glu Phe Val Ala Gln Phe Lys Phe Thr Val Leu
                 260                 265                 270

 Leu Met Pro Asn Gly Pro Met Arg Ile Thr Ser Gly Pro Phe Glu
                 275                 280                 285

 Pro Asp Leu Tyr Lys Ser Glu Met Glu Val Gln Asp Ala Glu Leu
                 290                 295                 300

 Lys Ala Leu Leu Gln Ser Ser Ala Ser Arg Lys Thr Gln Lys Lys
                 305                 310                 315

 Lys Lys Lys Lys Ala Ser Lys Thr Ala Glu Asn Ala Thr Ser Gly
                 320                 325                 330

 Glu Thr Leu Glu Glu Asn Glu Ala Gly Asp
                 335                 340

<210> 1793
<211> 937
<212> DNA
<213> Homo sapien

<400> 1793
 gttcttgcct ggtgtcggtg gttagtttct gcgacttgtg ttgggactgc 50

 tgataggaag atgtcttcag gaaatgctaa aattgggcac cctgccccca 100

 acttcaaagc cacagctgtt atgccagatg gtcagtttaa agatatcagc 150

 ctgtctgact acaaaggaaa atatgttgtg ttcttctttt accctcttga 200

 cttcaccttt gtgtgcccca cggagatcat tgctttcagt gatagggcag 250

 aagaatttaa gaaactcaac tgccaagtga ttggtgcttc tgtggattct 300

 cacttctgtc atctagcatg ggtcaataca cctaagaaac aaggaggact 350

 gggacccatg aacattcctt tggtatcaga cccgaagcgc accattgctc 400

 aggattatgg ggtcttaaag gctgatgaag gcatctcgtt caggggcctt 450

 tttatcattg atgataaggg tattcttcgg cagatcactg taaatgacct 500

 ccctgttggc cgctctgtgg atgagacttt gagactagtt caggccttcc 550

 agttcactga caaacatggg gaagtgtgcc cagctggctg gaaacctggc 600

 agtgatacca tcaagcctga tgtccaaaag agcaaagaat atttctccaa 650

 gcagaagtga gcgctgggct gttttagtgc caggctgcgg tgggcagcca 700

 tgagaacaaa acctcttctg tatttttttt ttccattagt aaaacacaag 750

 acttcagatt cagccgaatt gtggtgtctt acaaggcagg cctttcctac 800

 agggggtgga gagaccagcc tttcttcctt tggtaggaat ggcctgagtt 850

 ggcgttgtgg gcaggctact ggtttgtatg atgtattagt agagcaaccc 900

 attaatcttt tgtagtttgt attaaacttg aactgag 937

<210> 1794
<211> 199
<212> PRT
<213> Homo sapien

<400> 1794
 Met Ser Ser Gly Asn Ala Lys Ile Gly His Pro Ala Pro Asn Phe
   1               5                  10                  15

 Lys Ala Thr Ala Val Met Pro Asp Gly Gln Phe Lys Asp Ile Ser
                  20                  25                  30

 Leu Ser Asp Tyr Lys Gly Lys Tyr Val Val Phe Phe Phe Tyr Pro
                  35                  40                  45

 Leu Asp Phe Thr Phe Val Cys Pro Thr Glu Ile Ile Ala Phe Ser
                  50                  55                  60

 Asp Arg Ala Glu Glu Phe Lys Lys Leu Asn Cys Gln Val Ile Gly
                  65                  70                  75

 Ala Ser Val Asp Ser His Phe Cys His Leu Ala Trp Val Asn Thr
                  80                  85                  90

 Pro Lys Lys Gln Gly Gly Leu Gly Pro Met Asn Ile Pro Leu Val
                  95                 100                 105

 Ser Asp Pro Lys Arg Thr Ile Ala Gln Asp Tyr Gly Val Leu Lys
                 110                 115                 120

 Ala Asp Glu Gly Ile Ser Phe Arg Gly Leu Phe Ile Ile Asp Asp
                 125                 130                 135

 Lys Gly Ile Leu Arg Gln Ile Thr Val Asn Asp Leu Pro Val Gly
                 140                 145                 150

 Arg Ser Val Asp Glu Thr Leu Arg Leu Val Gln Ala Phe Gln Phe
                 155                 160                 165

 Thr Asp Lys His Gly Glu Val Cys Pro Ala Gly Trp Lys Pro Gly
                 170                 175                 180

 Ser Asp Thr Ile Lys Pro Asp Val Gln Lys Ser Lys Glu Tyr Phe
                 185                 190                 195

 Ser Lys Gln Lys


<210> 1795
<211> 5015
<212> DNA
<213> Homo sapien

<400> 1795
 cgggtggcgg ctcgggacgg aggacgcgct agtgttcttc tgtgtggcag 50

 ttcagaatga tggatcaagc tagatcagca ttctctaact tgtttggtgg 100

 agaaccattg tcatataccc ggttcagcct ggctcggcaa gtagatggcg 150

 ataacagtca tgtggagatg aaacttgctg tagatgaaga agaaaatgct 200

 gacaataaca caaaggccaa tgtcacaaaa ccaaaaaggt gtagtggaag 250

 tatctgctat gggactattg ctgtgatcgt ctttttcttg attggattta 300

 tgattggcta cttgggctat tgtaaagggg tagaaccaaa aactgagtgt 350

 gagagactgg caggaaccga gtctccagtg agggaggagc caggagagga 400

 cttccctgca gcacgtcgct tatattggga tgacctgaag agaaagttgt 450

 cggagaaact ggacagcaca gacttcaccg gcaccatcaa gctgctgaat 500

 gaaaattcat atgtccctcg tgaggctgga tctcaaaaag atgaaaatct 550

 tgcgttgtat gttgaaaatc aatttcgtga atttaaactc agcaaagtct 600

 ggcgtgatca acattttgtt aagattcagg tcaaagacag cgctcaaaac 650

 tcggtgatca tagttgataa gaacggtaga cttgtttacc tggtggagaa 700

 tcctgggggt tatgtggcgt atagtaaggc tgcaacagtt actggtaaac 750

 tggtccatgc taattttggt actaaaaaag attttgagga tttatacact 800

 cctgtgaatg gatctatagt gattgtcaga gcagggaaaa tcacctttgc 850

 agaaaaggtt gcaaatgctg aaagcttaaa tgcaattggt gtgttgatat 900

 acatggacca gactaaattt cccattgtta acgcagaact ttcattcttt 950

 ggacatgctc atctggggac aggtgaccct tacacacctg gattcccttc 1000

 cttcaatcac actcagtttc caccatctcg gtcatcagga ttgcctaata 1050

 tacctgtcca gacaatctcc agagctgctg cagaaaagct gtttgggaat 1100

 atggaaggag actgtccctc tgactggaaa acagactcta catgtaggat 1150

 ggtaacctca gaaagcaaga atgtgaagct cactgtgagc aatgtgctga 1200

 aagagataaa aattcttaac atctttggag ttattaaagg ctttgtagaa 1250

 ccagatcact atgttgtagt tggggcccag agagatgcat ggggccctgg 1300

 agctgcaaaa tccggtgtag gcacagctct cctattgaaa cttgcccaga 1350

 tgttctcaga tatggtctta aaagatgggt ttcagcccag cagaagcatt 1400

 atctttgcca gttggagtgc tggagacttt ggatcggttg gtgccactga 1450

 atggctagag ggataccttt cgtccctgca tttaaaggct ttcacttata 1500

 ttaatctgga taaagcggtt cttggtacca gcaacttcaa ggtttctgcc 1550

 agcccactgt tgtatacgct tattgagaaa acaatgcaaa atgtgaagca 1600

 tccggttact gggcaatttc tatatcagga cagcaactgg gccagcaaag 1650

 ttgagaaact cactttagac aatgctgctt tccctttcct tgcatattct 1700

 ggaatcccag cagtttcttt ctgtttttgc gaggacacag attatcctta 1750

 tttgggtacc accatggaca cctataagga actgattgag aggattcctg 1800

 agttgaacaa agtggcacga gcagctgcag aggtcgctgg tcagttcgtg 1850

 attaaactaa cccatgatgt tgaattgaac ctggactatg agaggtacaa 1900

 cagccaactg ctttcatttg tgagggatct gaaccaatac agagcagaca 1950

 taaaggaaat gggcctgagt ttacagtggc tgtattctgc tcgtggagac 2000

 ttcttccgtg ctacttccag actaacaaca gatttcggga atgctgagaa 2050

 aacagacaga tttgtcatga agaaactcaa tgatcgtgtc atgagagtgg 2100

 agtatcactt cctctctccc tacgtatctc caaaagagtc tcctttccga 2150

 catgtcttct ggggctccgg ctctcacacg ctgccagctt tactggagaa 2200

 cttgaaactg cgtaaacaaa ataacggtgc ttttaatgaa acgctgttca 2250

 gaaaccagtt ggctctagct acttggacta ttcagggagc tgcaaatgcc 2300

 ctctctggtg acgtttggga cattgacaat gagttttaaa tgtgataccc 2350

 atagcttcca tgagaacagc agggtagtct ggtttctaga cttgtgctga 2400

 tcgtgctaaa ttttcagtag ggctacaaaa cctgatgtta aaattccatc 2450

 ccatcatctt ggtactacta gatgtcttta ggcagcagct tttaatacag 2500

 ggtagataac ctgtacttca agttaaagtg aataaccact taaaaaatgt 2550

 ccatgatgga atattcccct atctctagaa ttttaagtgc tttgtaatgg 2600

 gaactgcctc tttcctgttg ttgttaatga aaatgtcaga aaccagttat 2650

 gtgaatgatc tctctgaatc ctaagggctg gtctctgctg aaggttgtaa 2700

 gtggtcgctt actttgagtg atcctccaac ttcatttgat gctaaatagg 2750

 agataccagg ttgaaagacc ttctccaaat gagatctaag cctttccata 2800

 aggaatgtag ctggtttcct cattcctgaa agaaacagtt aactttcaga 2850

 agagatgggc ttgttttctt gccaatgagg tctgaaatgg aggtccttct 2900

 gctggataaa atgaggttca actgttgatt gcaggaataa ggccttaata 2950

 tgttaacctc agtgtcattt atgaaaagag gggaccagaa gccaaagact 3000

 tagtatattt tcttttcctc tgtcccttcc cccataagcc tccatttagt 3050

 tctttgttat ttttgtttct tccaaagcac attgaaagag aaccagtttc 3100

 aggtgtttag ttgcagactc agtttgtcag actttaaaga ataatatgct 3150

 gccaaatttt ggccaaagtg ttaatcttag gggagagctt tctgtccttt 3200

 tggcactgag atatttattg tttatttatc agtgacagag ttcactataa 3250

 atggtgtttt tttaatagaa tataattatc ggaagcagtg ccttccataa 3300

 ttatgacagt tatactgtcg gtttttttta aataaaagca gcatctgcta 3350

 ataaaaccca acagatactg gaagttttgc atttatggtc aacacttaag 3400

 ggttttagaa aacagccgtc agccaaatgt aattgaataa agttgaagct 3450

 aagatttaga gatgaattaa atttaattag gggttgctaa gaagcgagca 3500

 ctgaccagat aagaatgctg gttttcctaa atgcagtgaa ttgtgaccaa 3550

 gttataaatc aatgtcactt aaaggctgtg gtagtactcc tgcaaaattt 3600

 tatagctcag tttatccaag gtgtaactct aattcccatt ttgcaaaatt 3650

 tccagtacct ttgtcacaat cctaacacat tatcgggagc agtgtcttcc 3700

 ataatgtata aagaacaagg tagtttttac ctaccacagt gtctgtatcg 3750

 gagacagtga tctccatatg ttacactaag ggtgtaagta attatcggga 3800

 acagtgtttc ccataatttt cttcatgcaa tgacatcttc aaagcttgaa 3850

 gatcgttagt atctaacatg tatcccaact cctataattc cctatctttt 3900

 agttttagtt gcagaaacat tttgtggtca ttaagcattg ggtgggtaaa 3950

 ttcaaccact gtaaaatgaa attactacaa aatttgaaat ttagcttggg 4000

 tttttgttac ctttatggtt tctccaggtc ctctacttaa tgagatagta 4050

 gcatacattt ataatgtttg ctattgacaa gtcattttaa ctttatcaca 4100

 ttatttgcat gttacctcct ataaacttag tgcggacaag ttttaatcca 4150

 gaattgacct tttgacttaa agcaggggga ctttgtatag aaggtttggg 4200

 ggctgtgggg aaggagagtc ccctgaaggt ctgacacgtc tgcctaccca 4250

 ttcgtggtga tcaattaaat gtaggtatga ataagttcga agctccgtga 4300

 gtgaaccatc attataaacg tgatgatcag ctgtttgtca tagggcagtt 4350

 ggaaacggcc tcctagggaa aagttcatag ggtctcttca ggttcttagt 4400

 gtcacttacc tagatttaca gcctcacttg aatgtgtcac tactcacagt 4450

 ctctttaatc ttcagtttta tctttaatct cctcttttat cttggactga 4500

 catttagcgt agctaagtga aaaggtcata gctgagattc ctggttcggg 4550

 tgttacgcac acgtacttaa atgaaagcat gtggcatgtt catcgtataa 4600

 cacaatatga atacagggca tgcattttgc agcagtgagt ctcttcagaa 4650

 aacccttttc tacagttagg gttgagttac ttcctatcaa gccagtacgt 4700

 gctaacaggc tcaatattcc tgaatgaaat atcagactag tgacaagctc 4750

 ctggtcttga gatgtcttct cgttaaggag atgggccttt tggaggtaaa 4800

 ggataaaatg aatgagttct gtcatgattc actattctag aacttgcatg 4850

 acctttactg tgttagctct ttgaatgttc ttgaaatttt agactttctt 4900

 tgtaaacaaa taatatgtcc ttatcattgt ataaaagctg ttatgtgcaa 4950

 cagtgtggag attccttgtc tgatttaata aaatacttaa acactgaaaa 5000

 aaaaaaaaaa aaaaa 5015

<210> 1796
<211> 760
<212> PRT
<213> Homo sapien

<400> 1796
 Met Met Asp Gln Ala Arg Ser Ala Phe Ser Asn Leu Phe Gly Gly
   1               5                  10                  15

 Glu Pro Leu Ser Tyr Thr Arg Phe Ser Leu Ala Arg Gln Val Asp
                  20                  25                  30

 Gly Asp Asn Ser His Val Glu Met Lys Leu Ala Val Asp Glu Glu
                  35                  40                  45

 Glu Asn Ala Asp Asn Asn Thr Lys Ala Asn Val Thr Lys Pro Lys
                  50                  55                  60

 Arg Cys Ser Gly Ser Ile Cys Tyr Gly Thr Ile Ala Val Ile Val
                  65                  70                  75

 Phe Phe Leu Ile Gly Phe Met Ile Gly Tyr Leu Gly Tyr Cys Lys
                  80                  85                  90

 Gly Val Glu Pro Lys Thr Glu Cys Glu Arg Leu Ala Gly Thr Glu
                  95                 100                 105

 Ser Pro Val Arg Glu Glu Pro Gly Glu Asp Phe Pro Ala Ala Arg
                 110                 115                 120

 Arg Leu Tyr Trp Asp Asp Leu Lys Arg Lys Leu Ser Glu Lys Leu
                 125                 130                 135

 Asp Ser Thr Asp Phe Thr Gly Thr Ile Lys Leu Leu Asn Glu Asn
                 140                 145                 150

 Ser Tyr Val Pro Arg Glu Ala Gly Ser Gln Lys Asp Glu Asn Leu
                 155                 160                 165

 Ala Leu Tyr Val Glu Asn Gln Phe Arg Glu Phe Lys Leu Ser Lys
                 170                 175                 180

 Val Trp Arg Asp Gln His Phe Val Lys Ile Gln Val Lys Asp Ser
                 185                 190                 195

 Ala Gln Asn Ser Val Ile Ile Val Asp Lys Asn Gly Arg Leu Val
                 200                 205                 210

 Tyr Leu Val Glu Asn Pro Gly Gly Tyr Val Ala Tyr Ser Lys Ala
                 215                 220                 225

 Ala Thr Val Thr Gly Lys Leu Val His Ala Asn Phe Gly Thr Lys
                 230                 235                 240

 Lys Asp Phe Glu Asp Leu Tyr Thr Pro Val Asn Gly Ser Ile Val
                 245                 250                 255

 Ile Val Arg Ala Gly Lys Ile Thr Phe Ala Glu Lys Val Ala Asn
                 260                 265                 270

 Ala Glu Ser Leu Asn Ala Ile Gly Val Leu Ile Tyr Met Asp Gln
                 275                 280                 285

 Thr Lys Phe Pro Ile Val Asn Ala Glu Leu Ser Phe Phe Gly His
                 290                 295                 300

 Ala His Leu Gly Thr Gly Asp Pro Tyr Thr Pro Gly Phe Pro Ser
                 305                 310                 315

 Phe Asn His Thr Gln Phe Pro Pro Ser Arg Ser Ser Gly Leu Pro
                 320                 325                 330

 Asn Ile Pro Val Gln Thr Ile Ser Arg Ala Ala Ala Glu Lys Leu
                 335                 340                 345

 Phe Gly Asn Met Glu Gly Asp Cys Pro Ser Asp Trp Lys Thr Asp
                 350                 355                 360

 Ser Thr Cys Arg Met Val Thr Ser Glu Ser Lys Asn Val Lys Leu
                 365                 370                 375

 Thr Val Ser Asn Val Leu Lys Glu Ile Lys Ile Leu Asn Ile Phe
                 380                 385                 390

 Gly Val Ile Lys Gly Phe Val Glu Pro Asp His Tyr Val Val Val
                 395                 400                 405

 Gly Ala Gln Arg Asp Ala Trp Gly Pro Gly Ala Ala Lys Ser Gly
                 410                 415                 420

 Val Gly Thr Ala Leu Leu Leu Lys Leu Ala Gln Met Phe Ser Asp
                 425                 430                 435

 Met Val Leu Lys Asp Gly Phe Gln Pro Ser Arg Ser Ile Ile Phe
                 440                 445                 450

 Ala Ser Trp Ser Ala Gly Asp Phe Gly Ser Val Gly Ala Thr Glu
                 455                 460                 465

 Trp Leu Glu Gly Tyr Leu Ser Ser Leu His Leu Lys Ala Phe Thr
                 470                 475                 480

 Tyr Ile Asn Leu Asp Lys Ala Val Leu Gly Thr Ser Asn Phe Lys
                 485                 490                 495

 Val Ser Ala Ser Pro Leu Leu Tyr Thr Leu Ile Glu Lys Thr Met
                 500                 505                 510

 Gln Asn Val Lys His Pro Val Thr Gly Gln Phe Leu Tyr Gln Asp
                 515                 520                 525

 Ser Asn Trp Ala Ser Lys Val Glu Lys Leu Thr Leu Asp Asn Ala
                 530                 535                 540

 Ala Phe Pro Phe Leu Ala Tyr Ser Gly Ile Pro Ala Val Ser Phe
                 545                 550                 555

 Cys Phe Cys Glu Asp Thr Asp Tyr Pro Tyr Leu Gly Thr Thr Met
                 560                 565                 570

 Asp Thr Tyr Lys Glu Leu Ile Glu Arg Ile Pro Glu Leu Asn Lys
                 575                 580                 585

 Val Ala Arg Ala Ala Ala Glu Val Ala Gly Gln Phe Val Ile Lys
                 590                 595                 600

 Leu Thr His Asp Val Glu Leu Asn Leu Asp Tyr Glu Arg Tyr Asn
                 605                 610                 615

 Ser Gln Leu Leu Ser Phe Val Arg Asp Leu Asn Gln Tyr Arg Ala
                 620                 625                 630

 Asp Ile Lys Glu Met Gly Leu Ser Leu Gln Trp Leu Tyr Ser Ala
                 635                 640                 645

 Arg Gly Asp Phe Phe Arg Ala Thr Ser Arg Leu Thr Thr Asp Phe
                 650                 655                 660

 Gly Asn Ala Glu Lys Thr Asp Arg Phe Val Met Lys Lys Leu Asn
                 665                 670                 675

 Asp Arg Val Met Arg Val Glu Tyr His Phe Leu Ser Pro Tyr Val
                 680                 685                 690

 Ser Pro Lys Glu Ser Pro Phe Arg His Val Phe Trp Gly Ser Gly
                 695                 700                 705

 Ser His Thr Leu Pro Ala Leu Leu Glu Asn Leu Lys Leu Arg Lys
                 710                 715                 720

 Gln Asn Asn Gly Ala Phe Asn Glu Thr Leu Phe Arg Asn Gln Leu
                 725                 730                 735

 Ala Leu Ala Thr Trp Thr Ile Gln Gly Ala Ala Asn Ala Leu Ser
                 740                 745                 750

 Gly Asp Val Trp Asp Ile Asp Asn Glu Phe
                 755                 760

<210> 1797
<211> 2742
<212> DNA
<213> Homo sapien

<400> 1797
 gtcactcgta taaaaaccta tgctttgaag gttctcgtgt gtctcggcct 50

 gcaggtctcg ctcagagctg tgtccctgaa catccaccct gctggggtgg 100

 cttgacgcac ttctgtgcaa atctgttcgc tcgcaaccct acctacctct 150

 ctcccgaacc ggagaaaacc ttcggcgggg tccttccggg ttttgtgtcg 200

 aatctgcggc ggcgacccgg cgccgcgtca cgcggtggtg aatgtgcggc 250

 agtacgcgcg ccgcgtcgtt tacgcggcga tttcatcatg ctccgagccg 300

 gcggcgcgcg ccgcttccgt cgccaccctc tctggacagc ccagggccgc 350

 aggctcatgc cctctccgcg tccagtgctg cttagaggtg ctcgcgccgc 400

 tctgctgctg ctgctgccgc cccggctctt agcccgaccc tcgctcctcc 450

 tccgccggtc cctcagcgcg gcctcctgcg ccccgatctc cttgcccgcc 500

 gccgcctccc ggagcagcat ggacggcgcg ggggctgagg aggtgctggc 550

 acctctgagg ctagcagtgc gccagcaggg agatcttgtg cgaaaactca 600

 aagaagataa agcaccccaa gtagacgtag acaaagcagt ggctgagctc 650

 aaagcccgca agagggttct ggaagcaaag gagctggcgt tacagcccaa 700

 agatgatatt gtagaccgag caaaaatgga agataccctg aagaggaggt 750

 ttttctatga tcaagctttt gctatttatg gaggtgttag tggtctgtat 800

 gactttgggc cagttggctg tgctttgaag aacaatatta ttcagacctg 850

 gaggcagcac tttatccaag aggaacagat cctggagatc gattgcacca 900

 tgctcacccc tgagccagtt ttaaagacct ctggccatgt agacaaattt 950

 gctgacttca tggtgaaaga cgtaaaaaat ggagaatgtt ttcgtgctga 1000

 ccatctatta aaagctcatt tacagaaatt gatgtctgat aagaagtgtt 1050

 ctgtcgaaaa gaaatcagaa atggaaagtg ttttggccca gcttgataac 1100

 tatggacagc aagaacttgc ggatcttttt gtgaactata atgtaaaatc 1150

 tcccattact ggaaatgatc tatcccctcc agtgtctttt aacttaatgt 1200

 tcaagacttt cattgggcct ggaggaaaca tgcctgggta cttgagacca 1250

 gaaactgcac aggggatttt cttgaatttc aaacgacttt tggagttcaa 1300

 ccaaggaaag ttgccttttg ctgctgccca gattggaaat tcttttagaa 1350

 atgagatctc ccctcgatct ggactgatca gagtcagaga attcacaatg 1400

 gcagaaattg agcactttgt agatcccagt gagaaagacc accccaagtt 1450

 ccagaatgtg gcagaccttc acctttattt gtattcagca aaagcccagg 1500

 tcagcggaca gtccgctcgg aaaatgcgcc tgggagatgc tgttgaacag 1550

 ggtgtgatta ataacacagt attaggctat ttcattggcc gcatctacct 1600

 ctacctcacg aaggttggaa tatctccaga taaactccgc ttccggcagc 1650

 acatggagaa tgagatggcc cattatgcct gtgactgttg ggatgcagaa 1700

 tccaaaacat cctacggttg gattgagatt gttggatgtg ctgatcgttc 1750

 ctgttatgac ctctcctgtc atgcacgagc caccaaagtc ccacttgtag 1800

 ctgagaaacc tctgaaagaa cccaaaacag tcaatgttgt tcagtttgaa 1850

 cccagtaagg gagcaattgg taaggcatat aagaaggatg caaaactggt 1900

 gatggagtat cttgccattt gtgatgagtg ctacattaca gaaatggaga 1950

 tgctgctgaa tgagaaaggg gaattcacaa ttgaaactga agggaaaaca 2000

 tttcagttaa caaaagacat gatcaatgtg aagagattcc agaaaacact 2050

 atatgtggaa gaagttgttc cgaatgtaat tgaaccttcc ttcggcctgg 2100

 gtaggatcat gtatacggta tttgaacata cattccatgt acgagaagga 2150

 gatgaacaga gaacattctt cagtttccct gctgtagttg ctccattcaa 2200

 atgttccgtc ctcccactga gccaaaacca ggagttcatg ccatttgtca 2250

 aggaattatc ggaagccctg accaggcatg gagtatctca caaagtagac 2300

 gattcctctg ggtcaatcgg aaggcgctat gccaggactg atgagattgg 2350

 cgtggctttt ggtgtcacca ttgactttga cacagtgaac aagacccccc 2400

 acactgcaac tctgagggac cgtgactcaa tgcggcagat aagagcagag 2450

 atctctgagc tgcccagcat agtccaagac ctagccaatg gcaacatcac 2500

 atgggctgat gtggaggcca ggtatcctct gtttgaaggg caagagactg 2550

 gtaaaaaaga gacaatcgag gaatgaggac aattttgaca acttttgacc 2600

 acttgcgcta ataaaaaaaa aaaaactact cttatgtcca ctttacaaaa 2650

 gaaaacagca ttgtgattac tcccagggac cgtattttat cttcagtggc 2700

 tgcctgattt tacccccaca attaaagttg aaggaatcct ga 2742

<210> 1798
<211> 685
<212> PRT
<213> Homo sapien

<400> 1798
 Met Asp Gly Ala Gly Ala Glu Glu Val Leu Ala Pro Leu Arg Leu
   1               5                  10                  15

 Ala Val Arg Gln Gln Gly Asp Leu Val Arg Lys Leu Lys Glu Asp
                  20                  25                  30

 Lys Ala Pro Gln Val Asp Val Asp Lys Ala Val Ala Glu Leu Lys
                  35                  40                  45

 Ala Arg Lys Arg Val Leu Glu Ala Lys Glu Leu Ala Leu Gln Pro
                  50                  55                  60

 Lys Asp Asp Ile Val Asp Arg Ala Lys Met Glu Asp Thr Leu Lys
                  65                  70                  75

 Arg Arg Phe Phe Tyr Asp Gln Ala Phe Ala Ile Tyr Gly Gly Val
                  80                  85                  90

 Ser Gly Leu Tyr Asp Phe Gly Pro Val Gly Cys Ala Leu Lys Asn
                  95                 100                 105

 Asn Ile Ile Gln Thr Trp Arg Gln His Phe Ile Gln Glu Glu Gln
                 110                 115                 120

 Ile Leu Glu Ile Asp Cys Thr Met Leu Thr Pro Glu Pro Val Leu
                 125                 130                 135

 Lys Thr Ser Gly His Val Asp Lys Phe Ala Asp Phe Met Val Lys
                 140                 145                 150

 Asp Val Lys Asn Gly Glu Cys Phe Arg Ala Asp His Leu Leu Lys
                 155                 160                 165

 Ala His Leu Gln Lys Leu Met Ser Asp Lys Lys Cys Ser Val Glu
                 170                 175                 180

 Lys Lys Ser Glu Met Glu Ser Val Leu Ala Gln Leu Asp Asn Tyr
                 185                 190                 195

 Gly Gln Gln Glu Leu Ala Asp Leu Phe Val Asn Tyr Asn Val Lys
                 200                 205                 210

 Ser Pro Ile Thr Gly Asn Asp Leu Ser Pro Pro Val Ser Phe Asn
                 215                 220                 225

 Leu Met Phe Lys Thr Phe Ile Gly Pro Gly Gly Asn Met Pro Gly
                 230                 235                 240

 Tyr Leu Arg Pro Glu Thr Ala Gln Gly Ile Phe Leu Asn Phe Lys
                 245                 250                 255

 Arg Leu Leu Glu Phe Asn Gln Gly Lys Leu Pro Phe Ala Ala Ala
                 260                 265                 270

 Gln Ile Gly Asn Ser Phe Arg Asn Glu Ile Ser Pro Arg Ser Gly
                 275                 280                 285

 Leu Ile Arg Val Arg Glu Phe Thr Met Ala Glu Ile Glu His Phe
                 290                 295                 300

 Val Asp Pro Ser Glu Lys Asp His Pro Lys Phe Gln Asn Val Ala
                 305                 310                 315

 Asp Leu His Leu Tyr Leu Tyr Ser Ala Lys Ala Gln Val Ser Gly
                 320                 325                 330

 Gln Ser Ala Arg Lys Met Arg Leu Gly Asp Ala Val Glu Gln Gly
                 335                 340                 345

 Val Ile Asn Asn Thr Val Leu Gly Tyr Phe Ile Gly Arg Ile Tyr
                 350                 355                 360

 Leu Tyr Leu Thr Lys Val Gly Ile Ser Pro Asp Lys Leu Arg Phe
                 365                 370                 375

 Arg Gln His Met Glu Asn Glu Met Ala His Tyr Ala Cys Asp Cys
                 380                 385                 390

 Trp Asp Ala Glu Ser Lys Thr Ser Tyr Gly Trp Ile Glu Ile Val
                 395                 400                 405

 Gly Cys Ala Asp Arg Ser Cys Tyr Asp Leu Ser Cys His Ala Arg
                 410                 415                 420

 Ala Thr Lys Val Pro Leu Val Ala Glu Lys Pro Leu Lys Glu Pro
                 425                 430                 435

 Lys Thr Val Asn Val Val Gln Phe Glu Pro Ser Lys Gly Ala Ile
                 440                 445                 450

 Gly Lys Ala Tyr Lys Lys Asp Ala Lys Leu Val Met Glu Tyr Leu
                 455                 460                 465

 Ala Ile Cys Asp Glu Cys Tyr Ile Thr Glu Met Glu Met Leu Leu
                 470                 475                 480

 Asn Glu Lys Gly Glu Phe Thr Ile Glu Thr Glu Gly Lys Thr Phe
                 485                 490                 495

 Gln Leu Thr Lys Asp Met Ile Asn Val Lys Arg Phe Gln Lys Thr
                 500                 505                 510

 Leu Tyr Val Glu Glu Val Val Pro Asn Val Ile Glu Pro Ser Phe
                 515                 520                 525

 Gly Leu Gly Arg Ile Met Tyr Thr Val Phe Glu His Thr Phe His
                 530                 535                 540

 Val Arg Glu Gly Asp Glu Gln Arg Thr Phe Phe Ser Phe Pro Ala
                 545                 550                 555

 Val Val Ala Pro Phe Lys Cys Ser Val Leu Pro Leu Ser Gln Asn
                 560                 565                 570

 Gln Glu Phe Met Pro Phe Val Lys Glu Leu Ser Glu Ala Leu Thr
                 575                 580                 585

 Arg His Gly Val Ser His Lys Val Asp Asp Ser Ser Gly Ser Ile
                 590                 595                 600

 Gly Arg Arg Tyr Ala Arg Thr Asp Glu Ile Gly Val Ala Phe Gly
                 605                 610                 615

 Val Thr Ile Asp Phe Asp Thr Val Asn Lys Thr Pro His Thr Ala
                 620                 625                 630

 Thr Leu Arg Asp Arg Asp Ser Met Arg Gln Ile Arg Ala Glu Ile
                 635                 640                 645

 Ser Glu Leu Pro Ser Ile Val Gln Asp Leu Ala Asn Gly Asn Ile
                 650                 655                 660

 Thr Trp Ala Asp Val Glu Ala Arg Tyr Pro Leu Phe Glu Gly Gln
                 665                 670                 675

 Glu Thr Gly Lys Lys Glu Thr Ile Glu Glu
                 680                 685

<210> 1799
<211> 1961
<212> DNA
<213> Homo sapien

<400> 1799
 ggcacgaggg ccctcccgag aaagggaagt gcattctcgc ttccgtagcg 50

 gtctccgccg gttgggggaa agtaattccg gctgttgcac catggcgtcc 100

 atggggaccc tcgccttcga tgaatatggg cgccctttcc tcatcatcaa 150

 ggatcaggac cgcaagtccc gtcttatggg acttgaggcc ctcaagtctc 200

 atataatggc agcaaaggct gtagcaaata caatgagaac atcacttgga 250

 ccaaatgggc ttgataagat gatggtggat aaggatgggg atgtgactgt 300

 aactaatgat ggggccacca tcttaagcat gatggatgtt gatcatcaga 350

 ttgccaagct gatggtggaa ctgtccaagt ctcaggatga tgaaattgga 400

 gatggaacca caggagtggt tgtcctggct ggtgccttgt tagaagaagc 450

 ggagcaattg ctagaccgag gcattcaccc aatcagaata gccgatggct 500

 atgagcaggc tgctcgcgtt gctattgaac acctggacaa gatcagcgat 550

 agcgtccttg ttgacataaa ggacaccgaa cccctgattc agacagcaaa 600

 aaccacgctg ggctccaaag tggtcaacag ttgtcaccga cagatggctg 650

 agattgctgt gaatgccgtc ctcactgtag cagatatgga gcggagagac 700

 gttgactttg agcttatcaa agtagaaggc aaagtgggcg gcaggctgga 750

 ggacactaaa ctgattaagg gcgtgattgt ggacaaggat ttcagtcacc 800

 cacagatgcc aaaaaaagtg gaagatgcga agattgcaat tctcacatgt 850

 ccatttgaac cacccaaacc aaaaacaaag cataagctgg atgtgacctc 900

 tgtcgaagat tataaagccc ttcagaaata cgaaaaggag aaatttgaag 950

 agatgattca acaaattaaa gagactggtg ctaacctagc aatttgtcag 1000

 tggggctttg atgatgaagc aaatcactta cttcttcaga acaacttgcc 1050

 tgcggttcgc tgggtaggag gacctgaaat tgagctgatt gccatcgcaa 1100

 caggagggcg gatcgtcccc aggttctcag agctcacagc cgagaagctg 1150

 ggctttgctg gtcttgtaca ggagatctca tttgggacaa ctaaggataa 1200

 aatgctggtc atcgagcagt gtaagaactc cagagctgta accattttta 1250

 ttagaggagg aaataagatg atcattgagg aggcgaaacg atcccttcac 1300

 gatgctttgt gtgtcatccg gaacctcatc cgcgataatc gtgtggtgta 1350

 tggaggaggg gctgctgaga tatcctgtgc cctggcagtt agccaagagg 1400

 cggataagtg ccccacctta gaacagtatg ccatgagagc gtttgccgac 1450

 gcactggagg tcatccccat ggccctctct gaaaacagtg gcatgaatcc 1500

 catccagact atgaccgaag tccgagccag acaggtgaag gagatgaacc 1550

 ctgctcttgg catcgactgt ttgcacaagg ggacaaatga tatgaagcaa 1600

 cagcatgtca tagaaacctt gattggcaaa aagcaacaga tatctcttgc 1650

 aacacaaatg gttagaatga ttttgaagat tgatgacatt cgtaagcctg 1700

 gagaatctga agaatgaaga cattgagaaa actatgtagc aagatccact 1750

 tctgtgatta agtaaatgga tgtctcgtga tgcgtctaca gttatttatt 1800

 gttacatcct tttccagaca ctgtagatgc tataataaaa atagctgttt 1850

 ggtaaccata gtttcacttg ttcaaagctg tgtaatcgtg ggggtactat 1900

 ctcaactgct tttgtattca ttgtattaaa agaatctgtt taaaaaaaaa 1950

 aaaaaaaaaa a 1961

<210> 1800
<211> 541
<212> PRT
<213> Homo sapien

<400> 1800
 Met Ala Ser Met Gly Thr Leu Ala Phe Asp Glu Tyr Gly Arg Pro
   1               5                  10                  15

 Phe Leu Ile Ile Lys Asp Gln Asp Arg Lys Ser Arg Leu Met Gly
                  20                  25                  30

 Leu Glu Ala Leu Lys Ser His Ile Met Ala Ala Lys Ala Val Ala
                  35                  40                  45

 Asn Thr Met Arg Thr Ser Leu Gly Pro Asn Gly Leu Asp Lys Met
                  50                  55                  60

 Met Val Asp Lys Asp Gly Asp Val Thr Val Thr Asn Asp Gly Ala
                  65                  70                  75

 Thr Ile Leu Ser Met Met Asp Val Asp His Gln Ile Ala Lys Leu
                  80                  85                  90

 Met Val Glu Leu Ser Lys Ser Gln Asp Asp Glu Ile Gly Asp Gly
                  95                 100                 105

 Thr Thr Gly Val Val Val Leu Ala Gly Ala Leu Leu Glu Glu Ala
                 110                 115                 120

 Glu Gln Leu Leu Asp Arg Gly Ile His Pro Ile Arg Ile Ala Asp
                 125                 130                 135

 Gly Tyr Glu Gln Ala Ala Arg Val Ala Ile Glu His Leu Asp Lys
                 140                 145                 150

 Ile Ser Asp Ser Val Leu Val Asp Ile Lys Asp Thr Glu Pro Leu
                 155                 160                 165

 Ile Gln Thr Ala Lys Thr Thr Leu Gly Ser Lys Val Val Asn Ser
                 170                 175                 180

 Cys His Arg Gln Met Ala Glu Ile Ala Val Asn Ala Val Leu Thr
                 185                 190                 195

 Val Ala Asp Met Glu Arg Arg Asp Val Asp Phe Glu Leu Ile Lys
                 200                 205                 210

 Val Glu Gly Lys Val Gly Gly Arg Leu Glu Asp Thr Lys Leu Ile
                 215                 220                 225

 Lys Gly Val Ile Val Asp Lys Asp Phe Ser His Pro Gln Met Pro
                 230                 235                 240

 Lys Lys Val Glu Asp Ala Lys Ile Ala Ile Leu Thr Cys Pro Phe
                 245                 250                 255

 Glu Pro Pro Lys Pro Lys Thr Lys His Lys Leu Asp Val Thr Ser
                 260                 265                 270

 Val Glu Asp Tyr Lys Ala Leu Gln Lys Tyr Glu Lys Glu Lys Phe
                 275                 280                 285

 Glu Glu Met Ile Gln Gln Ile Lys Glu Thr Gly Ala Asn Leu Ala
                 290                 295                 300

 Ile Cys Gln Trp Gly Phe Asp Asp Glu Ala Asn His Leu Leu Leu
                 305                 310                 315

 Gln Asn Asn Leu Pro Ala Val Arg Trp Val Gly Gly Pro Glu Ile
                 320                 325                 330

 Glu Leu Ile Ala Ile Ala Thr Gly Gly Arg Ile Val Pro Arg Phe
                 335                 340                 345

 Ser Glu Leu Thr Ala Glu Lys Leu Gly Phe Ala Gly Leu Val Gln
                 350                 355                 360

 Glu Ile Ser Phe Gly Thr Thr Lys Asp Lys Met Leu Val Ile Glu
                 365                 370                 375

 Gln Cys Lys Asn Ser Arg Ala Val Thr Ile Phe Ile Arg Gly Gly
                 380                 385                 390

 Asn Lys Met Ile Ile Glu Glu Ala Lys Arg Ser Leu His Asp Ala
                 395                 400                 405

 Leu Cys Val Ile Arg Asn Leu Ile Arg Asp Asn Arg Val Val Tyr
                 410                 415                 420

 Gly Gly Gly Ala Ala Glu Ile Ser Cys Ala Leu Ala Val Ser Gln
                 425                 430                 435

 Glu Ala Asp Lys Cys Pro Thr Leu Glu Gln Tyr Ala Met Arg Ala
                 440                 445                 450

 Phe Ala Asp Ala Leu Glu Val Ile Pro Met Ala Leu Ser Glu Asn
                 455                 460                 465

 Ser Gly Met Asn Pro Ile Gln Thr Met Thr Glu Val Arg Ala Arg
                 470                 475                 480

 Gln Val Lys Glu Met Asn Pro Ala Leu Gly Ile Asp Cys Leu His
                 485                 490                 495

 Lys Gly Thr Asn Asp Met Lys Gln Gln His Val Ile Glu Thr Leu
                 500                 505                 510

 Ile Gly Lys Lys Gln Gln Ile Ser Leu Ala Thr Gln Met Val Arg
                 515                 520                 525

 Met Ile Leu Lys Ile Asp Asp Ile Arg Lys Pro Gly Glu Ser Glu
                 530                 535                 540

 Glu


<210> 1801
<211> 1510
<212> DNA
<213> Homo sapien

<400> 1801
 ggactccctt ttctttggca agatggcgga gtacgacttg actactcgca 50

 tcgcgcactt tttggatcgg catctagtct ttccgcttct tgaatttctc 100

 tctgtaaagg agatatataa tgaaaaggaa ttattacaag gtaaattgga 150

 ccttcttagt gataccaaca tggtagactt tgctatggat gtatacaaaa 200

 acctttattc tgatgatatt cctcatgctt tgagagagaa aagaaccaca 250

 gtggttgcac aactgaaaca gcttcaggca gaaacagaac caattgtgaa 300

 gatgtttgaa gatccagaaa ctacaaggca aatgcagtca accagggatg 350

 gtaggatgct ctttgactac ctggcggaca agcatggttt taggcaggaa 400

 tatttagata cactctacag atatgcaaaa ttccagtacg aatgtgggaa 450

 ttactcagga gcagcagaat atctttattt ttttagagtg ctggttccag 500

 caacagatag aaatgcttta agttcactct ggggaaagct ggcctctgaa 550

 atcttaatgc agaattggga tgcagccatg gaagacctta cacggttaaa 600

 agagaccata gataataatt ctgtgagttc tccacttcag tctcttcagc 650

 agagaacatg gctcattcac tggtctctgt ttgttttctt caatcacccc 700

 aaaggtcgcg ataatattat tgacctcttc ctttatcagc cacaatatct 750

 taatgcaatt cagacaatgt gtccacacat tcttcgctat ttgactacag 800

 cagtcataac aaacaaggat gttcgaaaac gtcggcaggt tctaaaagat 850

 ctagttaaag ttattcaaca ggagtcttac acatataaag acccaattac 900

 agaatttgtt gaatgtttat atgttaactt tgactttgat ggggctcaga 950

 aaaagctgag ggaatgtgaa tcagtgcttg tgaatgactt cttcttggtg 1000

 gcttgtcttg aggatttcat tgaaaatgcc cgtctcttca tatttgagac 1050

 tttctgtcgc atccaccagt gtatcagcat taacatgttg gcagataaat 1100

 tgaacatgac tccagaagaa gctgaaaggt ggattgtaaa tttgattaga 1150

 aatgcaagac tggatgccaa gattgattct aaattaggtc atgtggttat 1200

 gggtaacaat gcagtctcac cctatcagca agtgattgaa aagaccaaaa 1250

 gcctttcctt tagaagccag atgttggcca tgaatattga gaagaaactt 1300

 aatcagaata gcaggtcaga ggctcctaac tgggcaactc aagattctgg 1350

 cttctactga agaaccataa agaaaagatg aaaaaaaaaa ctatcaaaga 1400

 aagatgaaat aataaaacta ttatataaag ggtgacttac attttggaaa 1450

 caacatatta cgtataaatt ttgaagaatt ggaataaaat tgattcattt 1500

 taaaaaaaaa 1510

<210> 1802
<211> 445
<212> PRT
<213> Homo sapien

<400> 1802
 Met Ala Glu Tyr Asp Leu Thr Thr Arg Ile Ala His Phe Leu Asp
   1               5                  10                  15

 Arg His Leu Val Phe Pro Leu Leu Glu Phe Leu Ser Val Lys Glu
                  20                  25                  30

 Ile Tyr Asn Glu Lys Glu Leu Leu Gln Gly Lys Leu Asp Leu Leu
                  35                  40                  45

 Ser Asp Thr Asn Met Val Asp Phe Ala Met Asp Val Tyr Lys Asn
                  50                  55                  60

 Leu Tyr Ser Asp Asp Ile Pro His Ala Leu Arg Glu Lys Arg Thr
                  65                  70                  75

 Thr Val Val Ala Gln Leu Lys Gln Leu Gln Ala Glu Thr Glu Pro
                  80                  85                  90

 Ile Val Lys Met Phe Glu Asp Pro Glu Thr Thr Arg Gln Met Gln
                  95                 100                 105

 Ser Thr Arg Asp Gly Arg Met Leu Phe Asp Tyr Leu Ala Asp Lys
                 110                 115                 120

 His Gly Phe Arg Gln Glu Tyr Leu Asp Thr Leu Tyr Arg Tyr Ala
                 125                 130                 135

 Lys Phe Gln Tyr Glu Cys Gly Asn Tyr Ser Gly Ala Ala Glu Tyr
                 140                 145                 150

 Leu Tyr Phe Phe Arg Val Leu Val Pro Ala Thr Asp Arg Asn Ala
                 155                 160                 165

 Leu Ser Ser Leu Trp Gly Lys Leu Ala Ser Glu Ile Leu Met Gln
                 170                 175                 180

 Asn Trp Asp Ala Ala Met Glu Asp Leu Thr Arg Leu Lys Glu Thr
                 185                 190                 195

 Ile Asp Asn Asn Ser Val Ser Ser Pro Leu Gln Ser Leu Gln Gln
                 200                 205                 210

 Arg Thr Trp Leu Ile His Trp Ser Leu Phe Val Phe Phe Asn His
                 215                 220                 225

 Pro Lys Gly Arg Asp Asn Ile Ile Asp Leu Phe Leu Tyr Gln Pro
                 230                 235                 240

 Gln Tyr Leu Asn Ala Ile Gln Thr Met Cys Pro His Ile Leu Arg
                 245                 250                 255

 Tyr Leu Thr Thr Ala Val Ile Thr Asn Lys Asp Val Arg Lys Arg
                 260                 265                 270

 Arg Gln Val Leu Lys Asp Leu Val Lys Val Ile Gln Gln Glu Ser
                 275                 280                 285

 Tyr Thr Tyr Lys Asp Pro Ile Thr Glu Phe Val Glu Cys Leu Tyr
                 290                 295                 300

 Val Asn Phe Asp Phe Asp Gly Ala Gln Lys Lys Leu Arg Glu Cys
                 305                 310                 315

 Glu Ser Val Leu Val Asn Asp Phe Phe Leu Val Ala Cys Leu Glu
                 320                 325                 330

 Asp Phe Ile Glu Asn Ala Arg Leu Phe Ile Phe Glu Thr Phe Cys
                 335                 340                 345

 Arg Ile His Gln Cys Ile Ser Ile Asn Met Leu Ala Asp Lys Leu
                 350                 355                 360

 Asn Met Thr Pro Glu Glu Ala Glu Arg Trp Ile Val Asn Leu Ile
                 365                 370                 375

 Arg Asn Ala Arg Leu Asp Ala Lys Ile Asp Ser Lys Leu Gly His
                 380                 385                 390

 Val Val Met Gly Asn Asn Ala Val Ser Pro Tyr Gln Gln Val Ile
                 395                 400                 405

 Glu Lys Thr Lys Ser Leu Ser Phe Arg Ser Gln Met Leu Ala Met
                 410                 415                 420

 Asn Ile Glu Lys Lys Leu Asn Gln Asn Ser Arg Ser Glu Ala Pro
                 425                 430                 435

 Asn Trp Ala Thr Gln Asp Ser Gly Phe Tyr
                 440                 445

<210> 1803
<211> 3899
<212> DNA
<213> Homo sapien

<400> 1803
 agcttgagcg cggcggcggc gttgttcagt cagagcgaga acattccaga 50

 ggtcgcccag ctccggcgct gacgggtgtg gaccgcggac gtcgctggga 100

 cagcccctcc ccgctgctcg gcggcggcat ctggcccggc cgctcctcgc 150

 tgcgcttcgc ctccgcctcc tcggactcgg actcgggttt atatcgcgcc 200

 tcacttcatc ccagtcccgg gcgagcagcg ttgggtttat gtctttattt 250

 gacgaaaacg agctgttgcg cagccattgg tacctgtatt ggggaaacat 300

 agcatacaag caagaagctt acagcctcag tggcgaaaat tttttcatgt 350

 cagagaccga gaactcttgc agtcgtttat gtcatccctt cttctccaga 400

 cagaagatac caaaaagttg caatcaaaga tctcttcatc ttattgataa 450

 agccactaat aagccaaaat gtctgtcaat gtcaaccgca gcgtgtcaga 500

 ccagttctat cgctacaaga tgccccgtct gattgccaag gttgagggca 550

 aaggcaatgg aatcaagaca gttatagtca acatggttga cgttgcaaag 600

 gcgcttaatc ggcctccaac gtatcccacc aaatattttg gttgtgagct 650

 gggagcacag acccagtttg atgttaagaa tgaccgttac attgtcaatg 700

 gatctcatga ggcgaataag ctgcaagaca tgttggatgg attcattaaa 750

 aaatttgttc tctgtcctga atgtgagaat cctgaaacag atttgcatgt 800

 caatccaaag aagcaaacaa taggtaattc ttgtaaagcc tgtggctatc 850

 gaggcatgct tgacacacat cataaactct gcacattcat tctcaaaaac 900

 ccacctgaga atagtgacag tggtacagga aagaaagaaa aagaaaagaa 950

 aaacagaaag ggcaaagaca aggaaaatgg ctccgtatcc agcagtgaga 1000

 caccaccacc accaccacca ccaaatgaaa ttaatcctcc tccacataca 1050

 atggaagaag aggaggatga tgactgggga gaagatacaa ctgaggaagc 1100

 tcaaaggcgt cgaatggatg aaatcagtga ccatgcaaaa gttctgacac 1150

 tcagtgatga tttggaaaga acaattgagg agagggtcaa tatcctcttt 1200

 gattttgtta agaaaaagaa agaagagggt gttattgatt catctgacaa 1250

 agaaatcgtt gctgaagcag aaagactgga tgtaaaagcc atgggccctc 1300

 ttgttctaac tgaagttctt tttaatgaga agattagaga acagattaag 1350

 aaatacaggc gccatttcct acgattttgt cacaacaaca aaaaagccca 1400

 acggtacctt cttcatggtt tggagtgtgt ggtagcaatg catcaagctc 1450

 agcttatctc caagattcca catatcttga aggagatgta cgatgcagac 1500

 cttttagaag aagaggtcat catcagctgg tcggaaaagg cctctaagaa 1550

 atatgtctcc aaagaacttg ccaaagagat tcgtgtcaaa gcagaaccat 1600

 ttataaaatg gttgaaggag gcagaggaag aatcttctgg tggcgaagaa 1650

 gaagatgaag atgagaacat tgaggtggtg tattcgaagg ctgccagtgt 1700

 accgaaagtt gagactgtaa agtcagacaa caaggatgac gacatcgata 1750

 ttgatgccat ttaaagggat ggatgcaacc tagcttaaca gtataatgct 1800

 gcaaattttc ctccattatc agccagaagt gcaacatgta tgtgcaaaag 1850

 ctaaaatggc ttaacatcat gctacacttt acactaaaaa tctattactg 1900

 tgagtggtct gttattaagc ccaatgagac atctagggag tccatacaca 1950

 tcagtgagca gatgtagttt gcttatttat agcatgtttc tttttgaaaa 2000

 actagtggtg gacacatttg gatcacattt atacagttat aaaaataaag 2050

 gtttgatttt ggtcgttctt cagatgtttg gctctgaatg acttaagctg 2100

 aagtaactgg ctccttactt taaatgttct gccatcattt cacctgatga 2150

 gcattcttgg agcctgccag atattgttag gtcctggggc tgcaaagagg 2200

 tcctcaacag gatgtaaagc aaacttaatt gtaattaatt tattcagccc 2250

 attaagaaag tactaaagtt ttatctctgt agttcctcaa attggcatct 2300

 ggtaatgtac attgtgaggt agactgataa tgaaatgaca gtgcaacatc 2350

 ttaaccaaga agtaaatatg acctcagtgt cctataaata atgtaagagc 2400

 aggatttgaa acttggagag ctgttttctc atttcatgta cacttgcccc 2450

 aaattgtctt tgaagtcgtg tgcattgcac gttggatgag ccagggaaat 2500

 tattacatta acaagcattt tgtgtgtgcg tagtagttac tttgtactga 2550

 gagaacttgc tttggggtgc aattaaacaa taaactgatt ttatttggga 2600

 gaaacaagga agggtgcact taactagcaa cctaagcatg atttttcagc 2650

 ttttgccctt agggtttaaa ttacaattcc aaaatgttag acatactgta 2700

 ttttttcgtt cagtgtggct ttaattttcc cctcttgcag tttgttctgt 2750

 aatgcctttt acatttggac acatagttta tgctttttag attttggttg 2800

 ctttcttgcc aaaataagtg ttaactgtgt ttcaaacttg attttctttc 2850

 ttttttcttt ttttttcttc cagaatgtct tatttaaaaa gaaagctaaa 2900

 agcatacttc taagtcagag cctctatttt ggtgtaagac ttgggatatt 2950

 ttttacttca cattgaatat agccaggcac ccaagaagtc tgatggccac 3000

 ctgagtgcag gtgacaagga cctgacagag cccatgcagg gctttagatt 3050

 tggacacaca agagttgata acttcctcat gaactccttg cctgatctaa 3100

 actcatatta tgggttctga ctgtttgagt aatcgtcttc aaggttaaac 3150

 ctcttggcag ttaccctttt cacaaagtgc acagtgggaa tcgagaatcg 3200

 atagggttaa ttttggagca gtggcttata ccattcacct ctgttttttt 3250

 gtgattattt cacagataat gagaccttaa taacaaatag gcgtaaaaaa 3300

 attttcacat tgaaatgata gaaacatttg atgtaataaa acttggttgg 3350

 cttgatattt taaggaattg aaacctagca atcttattgg agagacaaga 3400

 attggtctcc agctgccttt gatcaagatt cgggtgcaag tggagcagga 3450

 gccatatacc tggagggaat gtgctttgtc acaccaaaga ggattttttt 3500

 tttcttcaaa cttgtatgtt gcctaggttt caaattcttt gccgcaaggc 3550

 tgatctgctt tcattaactg gaattctgta ggagatactg gtgacctaag 3600

 ctaagttgca ctcagcatac tcagtgtcaa gctaatgagg ttctattata 3650

 aaggttctac ttttaatctg agggaaaaca tgttcagggc ttctagaaca 3700

 ctaaaaaatt tggcttaaac cagtgttcag tctggtgcca aacttcgaat 3750

 ggaatacaaa ttcacataat ctgaactttg ttcacaggtt atcctaatag 3800

 agtaattctt cactttgctc tattgaactg tcttaaggat ttgtttaaac 3850

 agctaagtta cttgattaaa ataatgataa aattgtaaaa aaaaaaaaa 3899

<210> 1804
<211> 431
<212> PRT
<213> Homo sapien

<400> 1804
 Met Ser Val Asn Val Asn Arg Ser Val Ser Asp Gln Phe Tyr Arg
   1               5                  10                  15

 Tyr Lys Met Pro Arg Leu Ile Ala Lys Val Glu Gly Lys Gly Asn
                  20                  25                  30

 Gly Ile Lys Thr Val Ile Val Asn Met Val Asp Val Ala Lys Ala
                  35                  40                  45

 Leu Asn Arg Pro Pro Thr Tyr Pro Thr Lys Tyr Phe Gly Cys Glu
                  50                  55                  60

 Leu Gly Ala Gln Thr Gln Phe Asp Val Lys Asn Asp Arg Tyr Ile
                  65                  70                  75

 Val Asn Gly Ser His Glu Ala Asn Lys Leu Gln Asp Met Leu Asp
                  80                  85                  90

 Gly Phe Ile Lys Lys Phe Val Leu Cys Pro Glu Cys Glu Asn Pro
                  95                 100                 105

 Glu Thr Asp Leu His Val Asn Pro Lys Lys Gln Thr Ile Gly Asn
                 110                 115                 120

 Ser Cys Lys Ala Cys Gly Tyr Arg Gly Met Leu Asp Thr His His
                 125                 130                 135

 Lys Leu Cys Thr Phe Ile Leu Lys Asn Pro Pro Glu Asn Ser Asp
                 140                 145                 150

 Ser Gly Thr Gly Lys Lys Glu Lys Glu Lys Lys Asn Arg Lys Gly
                 155                 160                 165

 Lys Asp Lys Glu Asn Gly Ser Val Ser Ser Ser Glu Thr Pro Pro
                 170                 175                 180

 Pro Pro Pro Pro Pro Asn Glu Ile Asn Pro Pro Pro His Thr Met
                 185                 190                 195

 Glu Glu Glu Glu Asp Asp Asp Trp Gly Glu Asp Thr Thr Glu Glu
                 200                 205                 210

 Ala Gln Arg Arg Arg Met Asp Glu Ile Ser Asp His Ala Lys Val
                 215                 220                 225

 Leu Thr Leu Ser Asp Asp Leu Glu Arg Thr Ile Glu Glu Arg Val
                 230                 235                 240

 Asn Ile Leu Phe Asp Phe Val Lys Lys Lys Lys Glu Glu Gly Val
                 245                 250                 255

 Ile Asp Ser Ser Asp Lys Glu Ile Val Ala Glu Ala Glu Arg Leu
                 260                 265                 270

 Asp Val Lys Ala Met Gly Pro Leu Val Leu Thr Glu Val Leu Phe
                 275                 280                 285

 Asn Glu Lys Ile Arg Glu Gln Ile Lys Lys Tyr Arg Arg His Phe
                 290                 295                 300

 Leu Arg Phe Cys His Asn Asn Lys Lys Ala Gln Arg Tyr Leu Leu
                 305                 310                 315

 His Gly Leu Glu Cys Val Val Ala Met His Gln Ala Gln Leu Ile
                 320                 325                 330

 Ser Lys Ile Pro His Ile Leu Lys Glu Met Tyr Asp Ala Asp Leu
                 335                 340                 345

 Leu Glu Glu Glu Val Ile Ile Ser Trp Ser Glu Lys Ala Ser Lys
                 350                 355                 360

 Lys Tyr Val Ser Lys Glu Leu Ala Lys Glu Ile Arg Val Lys Ala
                 365                 370                 375

 Glu Pro Phe Ile Lys Trp Leu Lys Glu Ala Glu Glu Glu Ser Ser
                 380                 385                 390

 Gly Gly Glu Glu Glu Asp Glu Asp Glu Asn Ile Glu Val Val Tyr
                 395                 400                 405

 Ser Lys Ala Ala Ser Val Pro Lys Val Glu Thr Val Lys Ser Asp
                 410                 415                 420

 Asn Lys Asp Asp Asp Ile Asp Ile Asp Ala Ile
                 425                 430

<210> 1805
<211> 1186
<212> DNA
<213> Homo sapien

<400> 1805
 aagtgcgatc ttcgggctgt cagagttggt ctgttactcg gtggtggcgg 50

 agtctacgga agccgttttc gcttcacttt tcctggctgt agagcgcttt 100

 ccccctggcg ggtgagagtg cagagacgaa ggtgcgagat gagcactatg 150

 ttcgcggaca ctctcctcat cgtttttatc tctgtgtgca cggctctgct 200

 cgcagagggc ataacctggg tcctggttta caggacagac aagtacaaga 250

 gactgaaggc agaagtggaa aaacagagta aaaaattgga aaagaagaag 300

 gaaacaataa cagagtcagc tggtcgacaa cagaaaaaga aaatagagag 350

 acaagaagag aaactgaaga ataacaacag agatctatca atggttcgaa 400

 tgaaatccat gtttgctatt ggcttttgtt ttactgccct aatgggaatg 450

 ttcaattcca tatttgatgg tagagtggtg gcaaagcttc cttttacccc 500

 tctttcttac atccaaggac tgtctcatcg aaatctgctg ggagatgaca 550

 ccacagactg ttccttcatt ttcctgtata ttctctgtac tatgtcgatt 600

 cgacagaaca ttcagaagat tctcggcctt gccccttcac gagccgccac 650

 caagcaggca ggtggatttc ttggcccacc acctccttct gggaagttct 700

 cttgaactca agaactcttt attttctatc attctttcta gacacacaca 750

 catcagactg gcaactgttt tgtagcaaga gccataggta gccttactac 800

 ttgggcctct ttctagtttt gaattatttc taagcctttt gggtatgatt 850

 agagtgaaaa tggcagccag caaacttgat agtgcttttg gtcctagatg 900

 atttttatca aataagtgga ttgattagtt aagttcaggt aatgtttatg 950

 taatgaaaaa caaatagcat ccttcttgtt tcatttacat aagtattttc 1000

 tgtgggaccg actctcaagg cactgtgtat gccctgcaag ttggctgtct 1050

 atgagcattt agagatttag aagaaaaatt tagtttgttt aacccttgta 1100

 actgtttgtt ttgttgttgt ttttttttca agccaaatac atgacataag 1150

 atcaataaag aggccaaatt tttagctgtt ttatgt 1186

<210> 1806
<211> 188
<212> PRT
<213> Homo sapien

<400> 1806
 Met Ser Thr Met Phe Ala Asp Thr Leu Leu Ile Val Phe Ile Ser
   1               5                  10                  15

 Val Cys Thr Ala Leu Leu Ala Glu Gly Ile Thr Trp Val Leu Val
                  20                  25                  30

 Tyr Arg Thr Asp Lys Tyr Lys Arg Leu Lys Ala Glu Val Glu Lys
                  35                  40                  45

 Gln Ser Lys Lys Leu Glu Lys Lys Lys Glu Thr Ile Thr Glu Ser
                  50                  55                  60

 Ala Gly Arg Gln Gln Lys Lys Lys Ile Glu Arg Gln Glu Glu Lys
                  65                  70                  75

 Leu Lys Asn Asn Asn Arg Asp Leu Ser Met Val Arg Met Lys Ser
                  80                  85                  90

 Met Phe Ala Ile Gly Phe Cys Phe Thr Ala Leu Met Gly Met Phe
                  95                 100                 105

 Asn Ser Ile Phe Asp Gly Arg Val Val Ala Lys Leu Pro Phe Thr
                 110                 115                 120

 Pro Leu Ser Tyr Ile Gln Gly Leu Ser His Arg Asn Leu Leu Gly
                 125                 130                 135

 Asp Asp Thr Thr Asp Cys Ser Phe Ile Phe Leu Tyr Ile Leu Cys
                 140                 145                 150

 Thr Met Ser Ile Arg Gln Asn Ile Gln Lys Ile Leu Gly Leu Ala
                 155                 160                 165

 Pro Ser Arg Ala Ala Thr Lys Gln Ala Gly Gly Phe Leu Gly Pro
                 170                 175                 180

 Pro Pro Pro Ser Gly Lys Phe Ser
                 185

<210> 1807
<211> 1439
<212> DNA
<213> Homo sapien

<400> 1807
 ggggtgtcgt ttcctttcgc tgatgcaaga gcctagtgcg gtggtgggag 50

 aggtatcggc aggggcagcg ctgccgccgg ggcctggggc tgacccgtct 100

 gacttcccgt ccgtgccgag cccactcgag ccgcagccat gtctggggac 150

 gagatgattt ttgatcctac tatgagcaag aagaaaaaga agaagaagaa 200

 gccttttatg ttagatgagg aaggggatac ccaaacagag gaaacccagc 250

 cttcagaaac aaaagaagtg gagccagagc caactgagga caaggatttg 300

 gaagctgatg aagaggacac taggaaaaaa gatgcttctg atgatctaga 350

 tgacttgaac ttctttaatc aaaagaaaaa gaagaaaaaa actaaaaaga 400

 tatttgatat tgatgaagct gaagaaggtg taaaggatct taagattgaa 450

 agtgatgttc aagaaccaac tgaaccagag gatgaccttg acattatgct 500

 tggcaataaa aagaagaaaa agaagaatgt taagttccca gatgaggatg 550

 aaatactaga gaaagatgaa gctctagaag atgaagacaa caaaaaagat 600

 gatggtatct cattcagtaa tcagacaggc cctgcttggg caggctcaga 650

 aagagactac acatacgagg agctgctgaa tcgagtgttc aacatcatga 700

 gggaaaagaa tccagatatg gttgctgggg agaaaaggaa atttgtcatg 750

 aaacctccac aagtcgtccg agtaggaacc aagaaaactt cttttgtcaa 800

 ctttacagat atctgtaaac tattacatcg tcagcccaaa catctccttg 850

 catttttgtt ggctgaattg ggtacaagtg gttctataga tggtaataac 900

 caacttgtaa tcaaaggaag attccaacag aaacagatag aaaatgtctt 950

 gagaagatat atcaaggaat atgtcacttg tcacacatgc cgatcaccgg 1000

 acacaatcct gcagaaggac acacgactct atttcctaca gtgcgaaact 1050

 tgtcattcta gatgttctgt tgccagtatc aaaaccggct tccaggctgt 1100

 cacgggcaag cgagcacagc tccgtgccaa agctaactaa tttgctaatc 1150

 actgattttg caaagcttgt tgtggagatg tggctggaca ggtttgccat 1200

 cagagtggat ataccgttgt attaaaaaca agataaaaaa gctgccaaga 1250

 tttttggcga gtggttggtc tgaagtcctt gcaagacgct gatgctcaag 1300

 ctgttgacat actcattgcc tactttaaca cctgtcagag aaacgtgata 1350

 tggggtaagg aggtgctttt ttaaaatcgt tcatagactt ctgtaaaatg 1400

 caagataaat taaagttatt ataacagtga ttctttcaa 1439

<210> 1808
<211> 333
<212> PRT
<213> Homo sapien

<400> 1808
 Met Ser Gly Asp Glu Met Ile Phe Asp Pro Thr Met Ser Lys Lys
   1               5                  10                  15

 Lys Lys Lys Lys Lys Lys Pro Phe Met Leu Asp Glu Glu Gly Asp
                  20                  25                  30

 Thr Gln Thr Glu Glu Thr Gln Pro Ser Glu Thr Lys Glu Val Glu
                  35                  40                  45

 Pro Glu Pro Thr Glu Asp Lys Asp Leu Glu Ala Asp Glu Glu Asp
                  50                  55                  60

 Thr Arg Lys Lys Asp Ala Ser Asp Asp Leu Asp Asp Leu Asn Phe
                  65                  70                  75

 Phe Asn Gln Lys Lys Lys Lys Lys Lys Thr Lys Lys Ile Phe Asp
                  80                  85                  90

 Ile Asp Glu Ala Glu Glu Gly Val Lys Asp Leu Lys Ile Glu Ser
                  95                 100                 105

 Asp Val Gln Glu Pro Thr Glu Pro Glu Asp Asp Leu Asp Ile Met
                 110                 115                 120

 Leu Gly Asn Lys Lys Lys Lys Lys Lys Asn Val Lys Phe Pro Asp
                 125                 130                 135

 Glu Asp Glu Ile Leu Glu Lys Asp Glu Ala Leu Glu Asp Glu Asp
                 140                 145                 150

 Asn Lys Lys Asp Asp Gly Ile Ser Phe Ser Asn Gln Thr Gly Pro
                 155                 160                 165

 Ala Trp Ala Gly Ser Glu Arg Asp Tyr Thr Tyr Glu Glu Leu Leu
                 170                 175                 180

 Asn Arg Val Phe Asn Ile Met Arg Glu Lys Asn Pro Asp Met Val
                 185                 190                 195

 Ala Gly Glu Lys Arg Lys Phe Val Met Lys Pro Pro Gln Val Val
                 200                 205                 210

 Arg Val Gly Thr Lys Lys Thr Ser Phe Val Asn Phe Thr Asp Ile
                 215                 220                 225

 Cys Lys Leu Leu His Arg Gln Pro Lys His Leu Leu Ala Phe Leu
                 230                 235                 240

 Leu Ala Glu Leu Gly Thr Ser Gly Ser Ile Asp Gly Asn Asn Gln
                 245                 250                 255

 Leu Val Ile Lys Gly Arg Phe Gln Gln Lys Gln Ile Glu Asn Val
                 260                 265                 270

 Leu Arg Arg Tyr Ile Lys Glu Tyr Val Thr Cys His Thr Cys Arg
                 275                 280                 285

 Ser Pro Asp Thr Ile Leu Gln Lys Asp Thr Arg Leu Tyr Phe Leu
                 290                 295                 300

 Gln Cys Glu Thr Cys His Ser Arg Cys Ser Val Ala Ser Ile Lys
                 305                 310                 315

 Thr Gly Phe Gln Ala Val Thr Gly Lys Arg Ala Gln Leu Arg Ala
                 320                 325                 330

 Lys Ala Asn


<210> 1809
<211> 1110
<212> DNA
<213> Homo sapien

<400> 1809
 gcaagcgcag attgtgggcg gctgtgtcag ctgacccaag gggccttcga 50

 ggtgccttag gccgcttgcc ttgctctcag aatcgctgcc gccatggcta 100

 gtcagtctca ggggattcag cagctgctgc aggccgagaa gcgggcagcc 150

 gagaaggtgt ccgaggcccg caaaagaaag aaccggaggc tgaagcaggc 200

 caaagaagaa gctcaggctg aaattgaaca gtaccgcctg cagagggaga 250

 aagaattcaa ggccaaggaa gctgcggcat tgggatcccg tggcagttgc 300

 agcactgaag tggagaagga gacccaggag aagatgacca tcctccagac 350

 atacttccgg cagaacaggg atgaagtctt ggacaacctc ttggcttttg 400

 tctgtgacat tcggccagaa atccatgaaa actaccgcat aaatggatag 450

 aagagagaag cacctgtgct gtggagtggc attttagatg ccctcacgaa 500

 tatgaagctt agcacagctc tagttacatt cttatgatat ggcattaaat 550

 tatttccata tattatataa taggtccttc cactttttgg agagtagcaa 600

 atctagcttt tttgtacaga cttagaaatt atctaaagat ttcatctttt 650

 tacctcatat ttcttaggaa tttaatggtt atatgttgtc tttttttcct 700

 atgtcttttg gctcaagcaa catgtatatc agtgttgact ttttctttct 750

 tagatctagt ttaaaaaaaa aaaaaaccac ataacaattc tttgaagaaa 800

 ggaagggatt aaataatttt tttccctaac actttcttga aggtcagggg 850

 ctttatctat gaaaaagtag taaatagttc tttgtaacct gtgtgaagca 900

 gcagccagcc ttaaagtagt ccattcttgc taatggttag aacagtgaat 950

 actagtggaa ttgtttgggc tgcttttagt ttctcttaat caaaattact 1000

 agatgataga attcaagaac ttgttacatg tattacttgg tgtatcgata 1050

 atcatttaaa agtaaagact ctgtcatgca aaaaaaaaaa aaaaaaaaaa 1100

 aaaaaaaaaa 1110

<210> 1810
<211> 118
<212> PRT
<213> Homo sapien

<400> 1810
 Met Ala Ser Gln Ser Gln Gly Ile Gln Gln Leu Leu Gln Ala Glu
   1               5                  10                  15

 Lys Arg Ala Ala Glu Lys Val Ser Glu Ala Arg Lys Arg Lys Asn
                  20                  25                  30

 Arg Arg Leu Lys Gln Ala Lys Glu Glu Ala Gln Ala Glu Ile Glu
                  35                  40                  45

 Gln Tyr Arg Leu Gln Arg Glu Lys Glu Phe Lys Ala Lys Glu Ala
                  50                  55                  60

 Ala Ala Leu Gly Ser Arg Gly Ser Cys Ser Thr Glu Val Glu Lys
                  65                  70                  75

 Glu Thr Gln Glu Lys Met Thr Ile Leu Gln Thr Tyr Phe Arg Gln
                  80                  85                  90

 Asn Arg Asp Glu Val Leu Asp Asn Leu Leu Ala Phe Val Cys Asp
                  95                 100                 105

 Ile Arg Pro Glu Ile His Glu Asn Tyr Arg Ile Asn Gly
                 110                 115

<210> 1811
<211> 1154
<212> DNA
<213> Homo sapien

<400> 1811
 gggggccttc cggcgggtga cattcagccg gcggttcggg gcgacggact 50

 ctccattcca gaaccatggc ccaatttgtc cgtaaccttg tggagaagac 100

 cccggcgctg gtgaacgctg ctgtgactta ctcgaagcct cgattggcca 150

 cattttggta ctacgccaag gttgagctgg ttcctcccac ccctgctgag 200

 atccctagag ctattcagag cctgaaaaaa atagccaata gtgctcagac 250

 tggtagcttc aaacagctca cagttaagga agctgtgctg aatggtttgg 300

 tggccactga ggtgttgatg tggttttatg tcggagagat tataggcaag 350

 cggggcatca ttggctatga tgtttgaaga ccaatcttta acatctgatt 400

 atatttgatt tattatttga gtgttgttgg accatgtgtg atcagactgc 450

 tatctgaata aaataagatt tgtcaaaact cagtgttttc tccatcagat 500

 actccatgaa aggtcacaat ttctcttgat attaagctgg gttgtcttta 550

 aacaacccta aatacacgtc tgtttagccc gcaattggaa aggatatatg 600

 tggcaatatt aacctggtac atgaatatat ggggataaca ttttaatttg 650

 aaggtttgga atatatatat ttaagcttta tttccagaac agtgagggtt 700

 aggtcttggg aaaactataa cttgccaaag tagaagaaat agtagtacca 750

 tatgccaaag tgatagagat gaatcatgtc agtagttaga ataacatttc 800

 aactgttttc tttgctaaaa tcacagaaag accctattga caacatctat 850

 gtctgtaaaa atgttagagt acttgtcatc ttgaatatag cctccccaag 900

 agagaacagg gtggtattct aagtatgttt ctttgtaaca tctttagcag 950

 taggacagag ccatacatgt gaaatctgat ttttatgtgt gttattcgtt 1000

 tgtctggttt tactaccttt gcaaaaacaa aataccccaa agatatttaa 1050

 acaaggttat aatttagcat cttccctgga tctaaatagt atattatatc 1100

 ctgaaataaa tgaaatgatt gctcaaaaaa aaaaaaaaaa aaaaaaaaaa 1150

 aaaa 1154

<210> 1812
<211> 103
<212> PRT
<213> Homo sapien

<400> 1812
 Met Ala Gln Phe Val Arg Asn Leu Val Glu Lys Thr Pro Ala Leu
   1               5                  10                  15

 Val Asn Ala Ala Val Thr Tyr Ser Lys Pro Arg Leu Ala Thr Phe
                  20                  25                  30

 Trp Tyr Tyr Ala Lys Val Glu Leu Val Pro Pro Thr Pro Ala Glu
                  35                  40                  45

 Ile Pro Arg Ala Ile Gln Ser Leu Lys Lys Ile Ala Asn Ser Ala
                  50                  55                  60

 Gln Thr Gly Ser Phe Lys Gln Leu Thr Val Lys Glu Ala Val Leu
                  65                  70                  75

 Asn Gly Leu Val Ala Thr Glu Val Leu Met Trp Phe Tyr Val Gly
                  80                  85                  90

 Glu Ile Ile Gly Lys Arg Gly Ile Ile Gly Tyr Asp Val
                  95                 100

<210> 1813
<211> 1839
<212> DNA
<213> Homo sapien

<400> 1813
 agcaacgggg tgcggcaggg tggggaacgc gggagcgggg ccagctccca 50

 ggaaagctgg tctgcgagcg gcccctgccc ggctcccagg tccctgcgcg 100

 accccgccct tcccgagacc ccagccgggc tgccgcccgc gtcccggaag 150

 ctccagcctg aaccatgttt ttcacttgtg gcccaaatga ggccatggtg 200

 gtctccgggt tctgccgaag ccccccagtc atggtggctg gagggcgtgt 250

 ctttgtcctg ccctgcatcc aacagatcca gaggatctct ctcaacacac 300

 tgaccctcaa tgtcaagagt gaaaaggttt acactcgcca tggggtcccc 350

 atctcagtca ctggcattgc ccaggtaaaa atccaggggc agaacaagga 400

 gatgttggcg gccgcctgtc agatgttcct ggggaagacg gaggctgaga 450

 ttgcccacat tgccctggag acgttagagg gccaccagag ggccatcatg 500

 gcccacatga ctgtggagga gatctataag gacaggcaga aattctcaga 550

 acaggttttc aaagtggcct cctcagacct ggtcaacatg ggcatcagtg 600

 tggttagcta cactctgaag gacattcacg atgaccagga ctatttgcac 650

 tctttgggga aggctcgaac agctcaagtc caaaaagatg cacggattgg 700

 agaagcagag gccaagagag atgctgggat ccgggaagct aaagccaagc 750

 aggaaaaggt gtctgctcag tacctgagtg agatcgagat ggccaaggca 800

 cagagagatt acgaactgaa gaaggccgcc tatgacatcg aggtcaacac 850

 ccgccgagca caggctgacc tggcctatca gcttcaggtg gccaagacta 900

 agcagcagat tgaggagcag cgggtgcagg tgcaggtggt ggagcgggcc 950

 cagcaggtgg cagtgcagga gcaggagatc gcccggcggg agaaggagct 1000

 ggaggcccgg gtgcggaagc cagcggaagc ggagcgctac aagctggagc 1050

 gcctagccga ggcagagaag tcccaactaa ttatgcaggc ggaggcagaa 1100

 gccgcgtctg tgcggatgcg tggggaagct gaggcctttg ccataggggc 1150

 ccgagcccga gccgaggctg agcagatggc caagaaggca gaagccttcc 1200

 agctgtacca agaggctgct cagctggaca tgctgctaga gaagctgccc 1250

 caggtggcag aggagatcag tggtcccttg acttcagcca ataagatcac 1300

 actggtgtcc agcggcagtg ggaccatggg ggcagccaaa gtgactgggg 1350

 aagtactgga cattctaact cgcctgccag agagtgtgga aagactcaca 1400

 ggcgtgagca tctcccaggt gaatcacaag cctttgagaa cagcctgagc 1450

 cttcagccct cacagatgcc cagcctcata gctgaagttg cctgaatgat 1500

 cctcctgttg catgtaaccc actggcctcc ctgagcatgt ccattgacag 1550

 tgaggtccca cccctcatct ctccttgcca aatagtttgt gccttgtctt 1600

 gaagggggtt gctccccttg ccaacctcac actgctatga ttgccaactc 1650

 cagcggtccc atgtcagcct tctgatgatc ccactccacc ccacctcaac 1700

 ttatttaact tcctaattaa atcagactgt ttgagcctgt tgtctagaat 1750

 attttcctga ccaagactga gggatgggct ggaggttttc aactttgcta 1800

 cccaaataaa ttgctgtaag taagtactaa aaaaaaaaa 1839

<210> 1814
<211> 427
<212> PRT
<213> Homo sapien

<400> 1814
 Met Phe Phe Thr Cys Gly Pro Asn Glu Ala Met Val Val Ser Gly
   1               5                  10                  15

 Phe Cys Arg Ser Pro Pro Val Met Val Ala Gly Gly Arg Val Phe
                  20                  25                  30

 Val Leu Pro Cys Ile Gln Gln Ile Gln Arg Ile Ser Leu Asn Thr
                  35                  40                  45

 Leu Thr Leu Asn Val Lys Ser Glu Lys Val Tyr Thr Arg His Gly
                  50                  55                  60

 Val Pro Ile Ser Val Thr Gly Ile Ala Gln Val Lys Ile Gln Gly
                  65                  70                  75

 Gln Asn Lys Glu Met Leu Ala Ala Ala Cys Gln Met Phe Leu Gly
                  80                  85                  90

 Lys Thr Glu Ala Glu Ile Ala His Ile Ala Leu Glu Thr Leu Glu
                  95                 100                 105

 Gly His Gln Arg Ala Ile Met Ala His Met Thr Val Glu Glu Ile
                 110                 115                 120

 Tyr Lys Asp Arg Gln Lys Phe Ser Glu Gln Val Phe Lys Val Ala
                 125                 130                 135

 Ser Ser Asp Leu Val Asn Met Gly Ile Ser Val Val Ser Tyr Thr
                 140                 145                 150

 Leu Lys Asp Ile His Asp Asp Gln Asp Tyr Leu His Ser Leu Gly
                 155                 160                 165

 Lys Ala Arg Thr Ala Gln Val Gln Lys Asp Ala Arg Ile Gly Glu
                 170                 175                 180

 Ala Glu Ala Lys Arg Asp Ala Gly Ile Arg Glu Ala Lys Ala Lys
                 185                 190                 195

 Gln Glu Lys Val Ser Ala Gln Tyr Leu Ser Glu Ile Glu Met Ala
                 200                 205                 210

 Lys Ala Gln Arg Asp Tyr Glu Leu Lys Lys Ala Ala Tyr Asp Ile
                 215                 220                 225

 Glu Val Asn Thr Arg Arg Ala Gln Ala Asp Leu Ala Tyr Gln Leu
                 230                 235                 240

 Gln Val Ala Lys Thr Lys Gln Gln Ile Glu Glu Gln Arg Val Gln
                 245                 250                 255

 Val Gln Val Val Glu Arg Ala Gln Gln Val Ala Val Gln Glu Gln
                 260                 265                 270

 Glu Ile Ala Arg Arg Glu Lys Glu Leu Glu Ala Arg Val Arg Lys
                 275                 280                 285

 Pro Ala Glu Ala Glu Arg Tyr Lys Leu Glu Arg Leu Ala Glu Ala
                 290                 295                 300

 Glu Lys Ser Gln Leu Ile Met Gln Ala Glu Ala Glu Ala Ala Ser
                 305                 310                 315

 Val Arg Met Arg Gly Glu Ala Glu Ala Phe Ala Ile Gly Ala Arg
                 320                 325                 330

 Ala Arg Ala Glu Ala Glu Gln Met Ala Lys Lys Ala Glu Ala Phe
                 335                 340                 345

 Gln Leu Tyr Gln Glu Ala Ala Gln Leu Asp Met Leu Leu Glu Lys
                 350                 355                 360

 Leu Pro Gln Val Ala Glu Glu Ile Ser Gly Pro Leu Thr Ser Ala
                 365                 370                 375

 Asn Lys Ile Thr Leu Val Ser Ser Gly Ser Gly Thr Met Gly Ala
                 380                 385                 390

 Ala Lys Val Thr Gly Glu Val Leu Asp Ile Leu Thr Arg Leu Pro
                 395                 400                 405

 Glu Ser Val Glu Arg Leu Thr Gly Val Ser Ile Ser Gln Val Asn
                 410                 415                 420

 His Lys Pro Leu Arg Thr Ala
                 425

<210> 1815
<211> 3582
<212> DNA
<213> Homo sapien

<400> 1815
 ctgctcgcgg cgccgcctcc tgctcctccc gctgctgctg ccgctgccgc 50

 cctgagtcac tgcctgcgca gctccggccg cctggctccc catactagtc 100

 gccgatattt ggagttctta caacatggca gacattgaca acaaagaaca 150

 gtctgaactt gatcaagatt tggatgatgt tgaagaagta gaagaagagg 200

 aaactggtga agaaacaaaa ctcaaagcac gtcagctaac tgttcagatg 250

 atgcaaaatc ctcagattct tgcagccctt caagaaagac ttgatggtct 300

 ggtagaaaca ccaacaggat acattgaaag cctgcctagg gtagttaaaa 350

 gacgagtgaa tgctctcaaa aacctgcaag ttaaatgtgc acagatagaa 400

 gccaaattct atgaggaagt tcacgatctt gaaaggaagt atgctgttct 450

 ctatcagcct ctatttgata agcgatttga aattattaat gcaatttatg 500

 aacctacgga agaagaatgt gaatggaaac cagatgaaga agatgagatt 550

 tcggaggaat tgaaagaaaa ggccaagatt gaagatgaga aaaaggatga 600

 agaaaaagaa gaccccaaag gaattcctga attttggtta actgttttta 650

 agaatgttga cttgctcagt gatatggttc aggaacacga tgaacctatt 700

 ctgaagcact tgaaagatat taaagtgaag ttctcagatg ctggccagcc 750

 tatgagtttt gtcttagaat ttcactttga acccaatgaa tattttacaa 800

 atgaagtgct gacaaagaca tacaggatga ggtcagaacc agatgattct 850

 gatccctttt cttttgatgg accagaaatt atgggttgta cagggtgcca 900

 gatagattgg aaaaaaggaa agaatgtcac tttgaaaact attaagaaga 950

 agcagaaaca caagggacgt gggacagttc gtactgtgac taaaacagtt 1000

 tccaatgact ctttctttaa cttttttgcc cctcctgaag ttcctgagag 1050

 tggagatctg gatgatgatg ctgaagctat ccttgctgca gacttcgaaa 1100

 ttggtcactt tttacgtgag cgtataatcc caagatcagt gttatatttt 1150

 actggagaag ctattgaaga tgatgatgat gattatgatg aagaaggtga 1200

 agaagcggat gaggaagggg aagaagaagg agatgaggaa aatgatccag 1250

 actatgaccc aaagaaggat caaaacccag cagagtgcaa gcagcagtga 1300

 agcaggatgt atgtggcctt gaggataacc tgcactgtaa tagcctaaac 1350

 acaactctta tttacttaca gccttatgtt tttgtatttt cttggtagac 1400

 taggtaattt ttttttaaag gacaggaaac tgatatttta aagaccaatt 1450

 tgttctacct agcattttaa ctagtttttc tgccagctat gttgaatgca 1500

 caaattctgt cacgcatgtt cattcattgc tacataattt ggttcttctg 1550

 gaatattttt atgtagctct tggagtacag ctatgaaaat taacaactgt 1600

 taaaggaaat accttttttt tttttttgta attttttcct tgaagaacca 1650

 aagtattttt tcagctggtt gttgaatagg gttaagtccg cttggattag 1700

 ctgtgccttt cattactttg ttacagaaat gcagtgactt atactaagac 1750

 aatttattgt ttaaaaaaaa aattggcaag acaactatat ggttaagaat 1800

 ttccagtatg accacaccca ataactgtta ttagagtgtt aatggattat 1850

 tgtgttttag gtgacatagt taactgtaaa gtaacctgac tcagtatagt 1900

 tactggtacc acagtgaggt gaataaaacg ggattttcag aagttagcct 1950

 gaatttaact gtatttttaa atttaacctc cattaactaa gcatcttttc 2000

 tttgtggtag ggtctacctt ctgcttccct ggaaaggatg aatttacatc 2050

 atttgacaag cctattttca agttatttgt tgtttgtttg cttgtttttg 2100

 tttttgcagc taaaataaaa atttcaaata caattttagt tcttacaaga 2150

 taatgtctta attttgtacc aattcaggta gaagtagagg cctaccttga 2200

 attaagggtt atactcagtt tttaacacat tgttgaagaa aaggtaccag 2250

 ctttggaacg agatgctata ctaataagca agtgtaaaaa aaaaaaaaaa 2300

 agaggaagaa aatcttaagt gattgatgct gttttctttt aaaaaaaaaa 2350

 aaaaaaattc attttctttg ggttagagct agagagaagg ccccaagctt 2400

 ctatggtttc ttctaattct tattgcttaa agtatgagta tgtcacttac 2450

 ccgtgcttct gtttactgtg taattaaaat gggtagtact gtttacctaa 2500

 ctacctcatg gatgtgttaa ggcatattga gttaaatctc atataatgtt 2550

 tctcaatctt gttaaaagct caaaattttg ggcctatttg taatgccagt 2600

 gtgacactaa gcattttgtt cacaccacgc tttgataact aaactggaaa 2650

 acaaaggtgt taagtacctc tgttctggat ctgggcagtc agcactcttt 2700

 ttagatcttt gtgtggctcc tatttttata gaagtggagg gatgcactat 2750

 ttcacaaggt ccaagatttg ttttcagata tttttgatga ctgtattgta 2800

 aatactacag ggatagcact atagtattgt agtcatgaga cttaaagtgg 2850

 aaataagact atttttgaca aaagatgcca ttaaatttca gactgtagag 2900

 ccacatttac aatacctcag gctaattact gttaattttg gggttgaact 2950

 ttttttgaca gtgagggtgg attattggat tgtcattaga ggaaggtcta 3000

 gatttcctgc tcttaataaa attacattga attgattttt agaggtaatg 3050

 aaaacttcct ttctgagaag ttagtgttaa ggtcttggaa tgtgaacaca 3100

 ttgtttgtag tgctatccat tcctctcctg agattttaac ttactactgg 3150

 aaatccttaa ccaattataa tagctttttt tctttatttt caaaatgatt 3200

 tcctttgctt tgattagaca ctatgtgctt ttttttttta accatagttc 3250

 atcgaaatgc agctttttct gaacttcaaa gatagaatcc catttttaat 3300

 gaactgaagt agcaaaatca tctttttcat tctttaggaa atagctattg 3350

 ccaaagtgaa ggtgtagata atacctagtc ttgttacata aaggggatgt 3400

 ggtttgcaga agaattttct ttataaaatt gaagttttaa gggacgtcag 3450

 tgtttatgcc atttttccag ttccaaaatg attccattcc attctagaaa 3500

 tttgaagtat gtaacctgaa atccttaata aaatttggat ttaattttat 3550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 3582

<210> 1816
<211> 391
<212> PRT
<213> Homo sapien

<400> 1816
 Met Ala Asp Ile Asp Asn Lys Glu Gln Ser Glu Leu Asp Gln Asp
   1               5                  10                  15

 Leu Asp Asp Val Glu Glu Val Glu Glu Glu Glu Thr Gly Glu Glu
                  20                  25                  30

 Thr Lys Leu Lys Ala Arg Gln Leu Thr Val Gln Met Met Gln Asn
                  35                  40                  45

 Pro Gln Ile Leu Ala Ala Leu Gln Glu Arg Leu Asp Gly Leu Val
                  50                  55                  60

 Glu Thr Pro Thr Gly Tyr Ile Glu Ser Leu Pro Arg Val Val Lys
                  65                  70                  75

 Arg Arg Val Asn Ala Leu Lys Asn Leu Gln Val Lys Cys Ala Gln
                  80                  85                  90

 Ile Glu Ala Lys Phe Tyr Glu Glu Val His Asp Leu Glu Arg Lys
                  95                 100                 105

 Tyr Ala Val Leu Tyr Gln Pro Leu Phe Asp Lys Arg Phe Glu Ile
                 110                 115                 120

 Ile Asn Ala Ile Tyr Glu Pro Thr Glu Glu Glu Cys Glu Trp Lys
                 125                 130                 135

 Pro Asp Glu Glu Asp Glu Ile Ser Glu Glu Leu Lys Glu Lys Ala
                 140                 145                 150

 Lys Ile Glu Asp Glu Lys Lys Asp Glu Glu Lys Glu Asp Pro Lys
                 155                 160                 165

 Gly Ile Pro Glu Phe Trp Leu Thr Val Phe Lys Asn Val Asp Leu
                 170                 175                 180

 Leu Ser Asp Met Val Gln Glu His Asp Glu Pro Ile Leu Lys His
                 185                 190                 195

 Leu Lys Asp Ile Lys Val Lys Phe Ser Asp Ala Gly Gln Pro Met
                 200                 205                 210

 Ser Phe Val Leu Glu Phe His Phe Glu Pro Asn Glu Tyr Phe Thr
                 215                 220                 225

 Asn Glu Val Leu Thr Lys Thr Tyr Arg Met Arg Ser Glu Pro Asp
                 230                 235                 240

 Asp Ser Asp Pro Phe Ser Phe Asp Gly Pro Glu Ile Met Gly Cys
                 245                 250                 255

 Thr Gly Cys Gln Ile Asp Trp Lys Lys Gly Lys Asn Val Thr Leu
                 260                 265                 270

 Lys Thr Ile Lys Lys Lys Gln Lys His Lys Gly Arg Gly Thr Val
                 275                 280                 285

 Arg Thr Val Thr Lys Thr Val Ser Asn Asp Ser Phe Phe Asn Phe
                 290                 295                 300

 Phe Ala Pro Pro Glu Val Pro Glu Ser Gly Asp Leu Asp Asp Asp
                 305                 310                 315

 Ala Glu Ala Ile Leu Ala Ala Asp Phe Glu Ile Gly His Phe Leu
                 320                 325                 330

 Arg Glu Arg Ile Ile Pro Arg Ser Val Leu Tyr Phe Thr Gly Glu
                 335                 340                 345

 Ala Ile Glu Asp Asp Asp Asp Asp Tyr Asp Glu Glu Gly Glu Glu
                 350                 355                 360

 Ala Asp Glu Glu Gly Glu Glu Glu Gly Asp Glu Glu Asn Asp Pro
                 365                 370                 375

 Asp Tyr Asp Pro Lys Lys Asp Gln Asn Pro Ala Glu Cys Lys Gln
                 380                 385                 390

 Gln


<210> 1817
<211> 2068
<212> DNA
<213> Homo sapien

<400> 1817
 cggcagccct cctacctgcg cacgtggtgc cgctgctgct gcctcccgct 50

 cgccctgaac ccagtgcctg cagccatggc tcccggccag ctcgccttat 100

 ttagtgtctc tgacaaaacc ggccttgtgg aatttgcaag aaacctgacc 150

 gctcttggtt tgaatctggt cgcttccgga gggactgcaa aagctctcag 200

 ggatgctggt ctggcagtca gagatgtctc tgagttgacg ggatttcctg 250

 aaatgttggg gggacgtgtg aaaactttgc atcctgcagt ccatgctgga 300

 atcctagctc gtaatattcc agaagataat gctgacatgg ccagacttga 350

 tttcaatctt ataagagttg ttgcctgcaa tctctatccc tttgtaaaga 400

 cagtggcttc tccaggtgta actgttgagg aggctgtgga gcaaattgac 450

 attggtggag taaccttact gagagctgca gccaaaaacc acgctcgagt 500

 gacagtggtg tgtgaaccag aggactatgt ggtggtgtcc acggagatgc 550

 agagctccga gagtaaggac acctccttgg agactagacg ccagttagcc 600

 ttgaaggcat tcactcatac ggcacaatat gatgaagcaa tttcagatta 650

 tttcaggaaa cagtacagca aaggcgtatc tcagatgccc ttgagatatg 700

 gaatgaaccc acatcagacc cctgcccagc tgtacacact gcagcccaag 750

 cttcccatca cagttctaaa tggagcccct ggatttataa acttgtgcga 800

 tgctttgaac gcctggcagc tggtgaagga actcaaggag gctttaggta 850

 ttccagccgc tgcctctttc aaacatgtca gcccagcagg tgctgctgtt 900

 ggaattccac tcagtgaaga tgaggccaaa gtctgcatgg tttatgatct 950

 ctataaaacc ctcacaccca tctcagcggc atatgcaaga gcaagagggg 1000

 ctgataggat gtcttcattt ggtgattttg ttgcattgtc cgatgtttgt 1050

 gatgtaccaa ctgcaaaaat tatttccaga gaagtatctg atggtataat 1100

 tgccccagga tatgaagaag aagccttgac aatactttcc aaaaagaaaa 1150

 atggaaacta ttgtgtcctt cagatggacc aatcttacaa accagatgaa 1200

 aatgaagttc gaactctctt tggtcttcat ttaagccaga agagaaataa 1250

 tggtgtcgtc gacaagtcat tatttagcaa tgttgttacc aaaaataaag 1300

 atttgccaga gtctgccctc cgagacctca tcgtagccac cattgctgtc 1350

 aagtacactc agtctaactc tgtgtgctac gccaagaacg ggcaggttat 1400

 cggcattgga gcaggacagc agtctcgtat acactgcact cgccttgcag 1450

 gagataaggc aaactattgg tggcttagac accatccaca agtgctttcg 1500

 atgaagttta aaacaggagt gaagagagca gaaatctcca atgccatcga 1550

 tcaatatgtg actggaacca ttggcgagga tgaagatttg ataaagtgga 1600

 aggcactgtt tgaggaagtc cctgagttac tcactgaggc agagaagaag 1650

 gaatgggttg agaaactgac tgaagtttct atcagctctg atgccttctt 1700

 ccctttccga gataacgtag acagagctaa aaggagtggt gtggcgtaca 1750

 ttgcggctcc ctccggttct gctgctgaca aagttgtgat tgaggcctgc 1800

 gacgaactgg gaatcatcct cgctcatacg aaccttcggc tcttccacca 1850

 ctgattttac cacacactgt tttttggctt gcttatgtgt aggtgaacag 1900

 tcacgcctga aactttgagg ataacttttt aaaaaaataa aacagtatct 1950

 cttaaaacaa tgttttgatc tacataaaca ttgtaaaaat tttcaatcac 2000

 gctttttaac tttcttacca caaaaaaatg ataagtgggt gaagtgatgg 2050

 ttatgttaat tagcgtgc 2068

<210> 1818
<211> 592
<212> PRT
<213> Homo sapien

<400> 1818
 Met Ala Pro Gly Gln Leu Ala Leu Phe Ser Val Ser Asp Lys Thr
   1               5                  10                  15

 Gly Leu Val Glu Phe Ala Arg Asn Leu Thr Ala Leu Gly Leu Asn
                  20                  25                  30

 Leu Val Ala Ser Gly Gly Thr Ala Lys Ala Leu Arg Asp Ala Gly
                  35                  40                  45

 Leu Ala Val Arg Asp Val Ser Glu Leu Thr Gly Phe Pro Glu Met
                  50                  55                  60

 Leu Gly Gly Arg Val Lys Thr Leu His Pro Ala Val His Ala Gly
                  65                  70                  75

 Ile Leu Ala Arg Asn Ile Pro Glu Asp Asn Ala Asp Met Ala Arg
                  80                  85                  90

 Leu Asp Phe Asn Leu Ile Arg Val Val Ala Cys Asn Leu Tyr Pro
                  95                 100                 105

 Phe Val Lys Thr Val Ala Ser Pro Gly Val Thr Val Glu Glu Ala
                 110                 115                 120

 Val Glu Gln Ile Asp Ile Gly Gly Val Thr Leu Leu Arg Ala Ala
                 125                 130                 135

 Ala Lys Asn His Ala Arg Val Thr Val Val Cys Glu Pro Glu Asp
                 140                 145                 150

 Tyr Val Val Val Ser Thr Glu Met Gln Ser Ser Glu Ser Lys Asp
                 155                 160                 165

 Thr Ser Leu Glu Thr Arg Arg Gln Leu Ala Leu Lys Ala Phe Thr
                 170                 175                 180

 His Thr Ala Gln Tyr Asp Glu Ala Ile Ser Asp Tyr Phe Arg Lys
                 185                 190                 195

 Gln Tyr Ser Lys Gly Val Ser Gln Met Pro Leu Arg Tyr Gly Met
                 200                 205                 210

 Asn Pro His Gln Thr Pro Ala Gln Leu Tyr Thr Leu Gln Pro Lys
                 215                 220                 225

 Leu Pro Ile Thr Val Leu Asn Gly Ala Pro Gly Phe Ile Asn Leu
                 230                 235                 240

 Cys Asp Ala Leu Asn Ala Trp Gln Leu Val Lys Glu Leu Lys Glu
                 245                 250                 255

 Ala Leu Gly Ile Pro Ala Ala Ala Ser Phe Lys His Val Ser Pro
                 260                 265                 270

 Ala Gly Ala Ala Val Gly Ile Pro Leu Ser Glu Asp Glu Ala Lys
                 275                 280                 285

 Val Cys Met Val Tyr Asp Leu Tyr Lys Thr Leu Thr Pro Ile Ser
                 290                 295                 300

 Ala Ala Tyr Ala Arg Ala Arg Gly Ala Asp Arg Met Ser Ser Phe
                 305                 310                 315

 Gly Asp Phe Val Ala Leu Ser Asp Val Cys Asp Val Pro Thr Ala
                 320                 325                 330

 Lys Ile Ile Ser Arg Glu Val Ser Asp Gly Ile Ile Ala Pro Gly
                 335                 340                 345

 Tyr Glu Glu Glu Ala Leu Thr Ile Leu Ser Lys Lys Lys Asn Gly
                 350                 355                 360

 Asn Tyr Cys Val Leu Gln Met Asp Gln Ser Tyr Lys Pro Asp Glu
                 365                 370                 375

 Asn Glu Val Arg Thr Leu Phe Gly Leu His Leu Ser Gln Lys Arg
                 380                 385                 390

 Asn Asn Gly Val Val Asp Lys Ser Leu Phe Ser Asn Val Val Thr
                 395                 400                 405

 Lys Asn Lys Asp Leu Pro Glu Ser Ala Leu Arg Asp Leu Ile Val
                 410                 415                 420

 Ala Thr Ile Ala Val Lys Tyr Thr Gln Ser Asn Ser Val Cys Tyr
                 425                 430                 435

 Ala Lys Asn Gly Gln Val Ile Gly Ile Gly Ala Gly Gln Gln Ser
                 440                 445                 450

 Arg Ile His Cys Thr Arg Leu Ala Gly Asp Lys Ala Asn Tyr Trp
                 455                 460                 465

 Trp Leu Arg His His Pro Gln Val Leu Ser Met Lys Phe Lys Thr
                 470                 475                 480

 Gly Val Lys Arg Ala Glu Ile Ser Asn Ala Ile Asp Gln Tyr Val
                 485                 490                 495

 Thr Gly Thr Ile Gly Glu Asp Glu Asp Leu Ile Lys Trp Lys Ala
                 500                 505                 510

 Leu Phe Glu Glu Val Pro Glu Leu Leu Thr Glu Ala Glu Lys Lys
                 515                 520                 525

 Glu Trp Val Glu Lys Leu Thr Glu Val Ser Ile Ser Ser Asp Ala
                 530                 535                 540

 Phe Phe Pro Phe Arg Asp Asn Val Asp Arg Ala Lys Arg Ser Gly
                 545                 550                 555

 Val Ala Tyr Ile Ala Ala Pro Ser Gly Ser Ala Ala Asp Lys Val
                 560                 565                 570

 Val Ile Glu Ala Cys Asp Glu Leu Gly Ile Ile Leu Ala His Thr
                 575                 580                 585

 Asn Leu Arg Leu Phe His His
                 590

<210> 1819
<211> 2045
<212> DNA
<213> Homo sapien

<400> 1819
 tttctccccc gttccccgcc gctgcagcgg tcgccttcgg agcgaagggt 50

 accgacccgg cagaagctcg gagctctcgg ggtatcgagg aggcaggccc 100

 gcgggcgcac gggcgagcgg gccgggagcc ggaggggcgg aggagccggc 150

 agcagcggcg cggcgggctc caggcgaggc ggtcgacgct cctgaaaact 200

 tgcgcgcgcg ctcgcgccac tgcgcccgga gcgatgaaga tggtcgcgcc 250

 ctggacgcgg ttctactcca acagctgctg cttgtgctgc catgtccgca 300

 ccggcaccat cctgctcggc gtctggtatc tgatcatcaa tgctgtggta 350

 ctgttgattt tattgagtgc cctggctgat ccggatcagt ataacttttc 400

 aagttctgaa ctgggaggtg actttgagtt catggatgat gccaacatgt 450

 gcattgccat tgcgatttct cttctcatga tcctgatatg tgctatggct 500

 acttacggag cgtacaagca acgcgcagcc tggatcatcc cattcttctg 550

 ttaccagatc tttgactttg ccctgaacat gttggttgca atcactgtgc 600

 ttatttatcc aaactccatt caggaataca tacggcaact gcctcctaat 650

 tttccctaca gagatgatgt catgtcagtg aatcctacct gtttggtcct 700

 tattattctt ctgtttatta gcattatctt gacttttaag ggttacttga 750

 ttagctgtgt ttggaactgc taccgataca tcaatggtag gaactcctct 800

 gatgtcctgg tttatgttac cagcaatgac actacggtgc tgctaccccc 850

 gtatgatgat gccactgtga atggtgctgc caaggagcca ccgccacctt 900

 acgtgtctgc ctaagccttc aagtgggcgg agctgagggc agcagcttga 950

 ctttgcagac atctgagcaa tagttctgtt atttcacttt tgccatgagc 1000

 ctctctgagc ttgtttgttg ctgaaatgct actttttaaa atttagatgt 1050

 tagattgaaa actgtagttt tcaacatatg ctttgctaga acactgtgat 1100

 agattaactg tagaattctt cctgtacgat tggggatata atgggcttca 1150

 ctaaccttcc ctaggcattg aaacttcccc caaatctgat ggacctagaa 1200

 gtctgctttt gtacctgctg ggccccaaag ttgggcattt ttctctctgt 1250

 tccctctctt ttgaaaatgt aaaataaaac caaaaataga caactttttc 1300

 ttcagccatt ccagcataga gaacaaaacc ttatggaaac aggaatgtca 1350

 attgtgtaat cattgttcta attaggtaaa tagaagtcct tatgtatgtg 1400

 ttacaagaat ttcccccaca acatccttta tgactgaagt tcaatgacag 1450

 tttgtgtttg ggtggtaaag gattttctcc atggcctgaa ttaagaccat 1500

 tagaaagcac caggccgtgg gagcagtgac catctgctga ctgttcttgt 1550

 ggatcttgtg tccagggaca tggggtgaca tgcctcgtat gtgttagagg 1600

 gtggaatgga tgtgtttggc gctgcatggg atctggtgcc cctcttctcc 1650

 tggattcaca tccccaccca gggcccgctt ttactaagtg ttctgcccta 1700

 gattggttca aggaggtcat ccaactgact ttatcaagtg gaattgggat 1750

 atatttgata tacttctgcc taacaacatg gaaaagggtt ttcttttccc 1800

 tgcaagctac atcctactgc tttgaacttc caagtatgtc tagtcacctt 1850

 ttaaaatgta aacattttca gaaaaatgag gattgccttc cttgtatgcg 1900

 ctttttacct tgactacctg aattgcaagg gatttttata tattcatatg 1950

 ttacaaagtc agcaactctc ctgttggttc attattgaat gtgctgtaaa 2000

 ttaagttgtt tgcaattaaa acaaggtttg cccacaaaaa aaaaa 2045

<210> 1820
<211> 283
<212> PRT
<213> Homo sapien

<400> 1820
 Met Val Asn Tyr Ala Trp Ala Gly Arg Ser Gln Arg Lys Leu Trp
   1               5                  10                  15

 Trp Arg Ser Val Ala Val Leu Thr Cys Lys Ser Val Val Arg Pro
                  20                  25                  30

 Gly Tyr Arg Gly Gly Leu Gln Ala Arg Arg Ser Thr Leu Leu Lys
                  35                  40                  45

 Thr Cys Ala Arg Ala Arg Ala Thr Ala Pro Gly Ala Met Lys Met
                  50                  55                  60

 Val Ala Pro Trp Thr Arg Phe Tyr Ser Asn Ser Cys Cys Leu Cys
                  65                  70                  75

 Cys His Val Arg Thr Gly Thr Ile Leu Leu Gly Val Trp Tyr Leu
                  80                  85                  90

 Ile Ile Asn Ala Val Val Leu Leu Ile Leu Leu Ser Ala Leu Ala
                  95                 100                 105

 Asp Pro Asp Gln Tyr Asn Phe Ser Ser Ser Glu Leu Gly Gly Asp
                 110                 115                 120

 Phe Glu Phe Met Asp Asp Ala Asn Met Cys Ile Ala Ile Ala Ile
                 125                 130                 135

 Ser Leu Leu Met Ile Leu Ile Cys Ala Met Ala Thr Tyr Gly Ala
                 140                 145                 150

 Tyr Lys Gln Arg Ala Ala Trp Ile Ile Pro Phe Phe Cys Tyr Gln
                 155                 160                 165

 Ile Phe Asp Phe Ala Leu Asn Met Leu Val Ala Ile Thr Val Leu
                 170                 175                 180

 Ile Tyr Pro Asn Ser Ile Gln Glu Tyr Ile Arg Gln Leu Pro Pro
                 185                 190                 195

 Asn Phe Pro Tyr Arg Asp Asp Val Met Ser Val Asn Pro Thr Cys
                 200                 205                 210

 Leu Val Leu Ile Ile Leu Leu Phe Ile Ser Ile Ile Leu Thr Phe
                 215                 220                 225

 Lys Gly Tyr Leu Ile Ser Cys Val Trp Asn Cys Tyr Arg Tyr Ile
                 230                 235                 240

 Asn Gly Arg Asn Ser Ser Asp Val Leu Val Tyr Val Thr Ser Asn
                 245                 250                 255

 Asp Thr Thr Val Leu Leu Pro Pro Tyr Asp Asp Ala Thr Val Asn
                 260                 265                 270

 Gly Ala Ala Lys Glu Pro Pro Pro Pro Tyr Val Ser Ala
                 275                 280

<210> 1821
<211> 1598
<212> DNA
<213> Homo sapien

<400> 1821
 cgtcggcggc cgcggccggg gacggtgtga gagcggtaag atggcggcgg 50

 cggcggtggt ggagttccag agagcccagt ctctactcag caccgaccgg 100

 gaggcctcca tcgacatcct ccactccatc gtgaagcgtg acattcagga 150

 aaacgatgaa gaggcagtgc aagtcaaaga gcagagcatc ctggaactgg 200

 gatctctcct ggcaaagact ggacaagctg cagagcttgg aggactcctg 250

 aagtatgtac gacccttctt gaattccatc agcaaggcta aagcagctcg 300

 cctggtccga tctcttcttg atctgtttct tgatatggaa gcagctacag 350

 ggcaggaggt cgagctgtgt ttagagtgca tcgaatgggc caagtcagag 400

 aaaagaactt tcttacgcca agctttggag gcaagactgg tgtctttgta 450

 ctttgatacc aagaggtacc aggaagcatt gcatttgggt tctcagctgc 500

 tgcgggagtt gaaaaagatg gacgacaaag ctcttttggt ggaagtacag 550

 cttttagaaa gcaaaacata ccatgccctg agcaacctgc cgaaagcccg 600

 agctgcctta acttctgctc gaaccacagc aaatgccatc tactgccccc 650

 ctaaattgca ggccaccttg gacatgcagt cgggtattat ccatgcagca 700

 gaagagaagg actggaaaac tgcgtactca tacttctatg aggcatttga 750

 gggttatgac tccatcgaca gccccaaggc catcacatct ctgaagtaca 800

 tgttgctgtg caaaatcatg ctcaacaccc cagaagatgt ccaggctttg 850

 gtgagcggga agcttgcact tcggtatgca gggaggcaga cagaagcatt 900

 aaaatgcgtg gctcaggcta gcaagaacag atcactggca gattttgaaa 950

 aggctctgac agattaccgg gcagagctcc gggatgaccc aatcatcagc 1000

 acacacttgg ccaagttgta tgataactta ctagaacaga atctgatccg 1050

 agtcattgag cctttttcca gagtacagat tgaacacata tctagtctca 1100

 tcaaactctc caaggccgac gtggaaagga aattatcaca gatgattctt 1150

 gacaagaaat ttcatgggat tttggaccag ggggagggtg tcctgattat 1200

 tttcgatgaa cccccagtag ataaaactta cgaagctgct ctggaaacaa 1250

 ttcagaacat gagcaaagta gtggattccc tctacaacaa agccaagaaa 1300

 ctgacataga gttggatctg tagcggtcct ttggagagtg tgtgtggcgg 1350

 gagagtgaaa ccttggggga aaatgctagg agattctttt ttctttttgt 1400

 tctacttttc gctcggaaag tttttaaatc ctcatttggt gcatctgtat 1450

 tccagccaat aggtgtgcca gttttcatgt aatctttact ggcccaactt 1500

 gggagtgggg aaattgctta aaaaaaaaga aaaagaaaaa aaaaaagatt 1550

 attctaaata aaaggaaaaa ggcttacact aaaaaaaaaa aaaaaaaa 1598

<210> 1822
<211> 422
<212> PRT
<213> Homo sapien

<400> 1822
 Met Ala Ala Ala Ala Val Val Glu Phe Gln Arg Ala Gln Ser Leu
   1               5                  10                  15

 Leu Ser Thr Asp Arg Glu Ala Ser Ile Asp Ile Leu His Ser Ile
                  20                  25                  30

 Val Lys Arg Asp Ile Gln Glu Asn Asp Glu Glu Ala Val Gln Val
                  35                  40                  45

 Lys Glu Gln Ser Ile Leu Glu Leu Gly Ser Leu Leu Ala Lys Thr
                  50                  55                  60

 Gly Gln Ala Ala Glu Leu Gly Gly Leu Leu Lys Tyr Val Arg Pro
                  65                  70                  75

 Phe Leu Asn Ser Ile Ser Lys Ala Lys Ala Ala Arg Leu Val Arg
                  80                  85                  90

 Ser Leu Leu Asp Leu Phe Leu Asp Met Glu Ala Ala Thr Gly Gln
                  95                 100                 105

 Glu Val Glu Leu Cys Leu Glu Cys Ile Glu Trp Ala Lys Ser Glu
                 110                 115                 120

 Lys Arg Thr Phe Leu Arg Gln Ala Leu Glu Ala Arg Leu Val Ser
                 125                 130                 135

 Leu Tyr Phe Asp Thr Lys Arg Tyr Gln Glu Ala Leu His Leu Gly
                 140                 145                 150

 Ser Gln Leu Leu Arg Glu Leu Lys Lys Met Asp Asp Lys Ala Leu
                 155                 160                 165

 Leu Val Glu Val Gln Leu Leu Glu Ser Lys Thr Tyr His Ala Leu
                 170                 175                 180

 Ser Asn Leu Pro Lys Ala Arg Ala Ala Leu Thr Ser Ala Arg Thr
                 185                 190                 195

 Thr Ala Asn Ala Ile Tyr Cys Pro Pro Lys Leu Gln Ala Thr Leu
                 200                 205                 210

 Asp Met Gln Ser Gly Ile Ile His Ala Ala Glu Glu Lys Asp Trp
                 215                 220                 225

 Lys Thr Ala Tyr Ser Tyr Phe Tyr Glu Ala Phe Glu Gly Tyr Asp
                 230                 235                 240

 Ser Ile Asp Ser Pro Lys Ala Ile Thr Ser Leu Lys Tyr Met Leu
                 245                 250                 255

 Leu Cys Lys Ile Met Leu Asn Thr Pro Glu Asp Val Gln Ala Leu
                 260                 265                 270

 Val Ser Gly Lys Leu Ala Leu Arg Tyr Ala Gly Arg Gln Thr Glu
                 275                 280                 285

 Ala Leu Lys Cys Val Ala Gln Ala Ser Lys Asn Arg Ser Leu Ala
                 290                 295                 300

 Asp Phe Glu Lys Ala Leu Thr Asp Tyr Arg Ala Glu Leu Arg Asp
                 305                 310                 315

 Asp Pro Ile Ile Ser Thr His Leu Ala Lys Leu Tyr Asp Asn Leu
                 320                 325                 330

 Leu Glu Gln Asn Leu Ile Arg Val Ile Glu Pro Phe Ser Arg Val
                 335                 340                 345

 Gln Ile Glu His Ile Ser Ser Leu Ile Lys Leu Ser Lys Ala Asp
                 350                 355                 360

 Val Glu Arg Lys Leu Ser Gln Met Ile Leu Asp Lys Lys Phe His
                 365                 370                 375

 Gly Ile Leu Asp Gln Gly Glu Gly Val Leu Ile Ile Phe Asp Glu
                 380                 385                 390

 Pro Pro Val Asp Lys Thr Tyr Glu Ala Ala Leu Glu Thr Ile Gln
                 395                 400                 405

 Asn Met Ser Lys Val Val Asp Ser Leu Tyr Asn Lys Ala Lys Lys
                 410                 415                 420

 Leu Thr


<210> 1823
<211> 2019
<212> DNA
<213> Homo sapien

<400> 1823
 acgtgtatcg ctgccgtcaa gatggagggg cctttgtccg tgttcggtga 50

 ccgcagcact ggggaaacga tccgctccca aaacgttatg gctgcagctt 100

 cgattgccaa tattgtaaaa agttctcttg gtccagttgg cttggataaa 150

 atgttggtgg atgatattgg tgatgtaacc attactaacg atggtgcaac 200

 catcctgaag ttactggagg tagaacatcc tgcagctaaa gttctttgtg 250

 agctggctga tctgcaagac aaagaagttg gagatggaac tacttcagtg 300

 gttattattg cagcagaact cctaaaaaat gcagatgaat tagtcaaaca 350

 gaaaattcat cccacatcag ttattagtgg ctatcgactt gcttgcaagg 400

 aagcagtgcg ttatatcaat gaaaacctaa ttgttaacac agatgaactg 450

 ggaagagatt gcctgattaa tgctgctaag acatccatgt cttccaaaat 500

 cattgggata aatggtgatt tctttgctaa catggtagta gatgctgtac 550

 ttgctattaa atacacagac ataagaggcc agccacgcta tccagtcaac 600

 tctgttaata ttttgaaagc ccatgggaga agtcaaatgg agagtatgct 650

 catcagtggc tatgcactca actgtgtggt gggatcccag ggcatgccca 700

 agagaatcgt aaatgcaaaa attgcttgcc ttgacttcag cctgcaaaaa 750

 acaaaaatga agcttggtgt acaggtggtc attacagacc ctgaaaaact 800

 ggaccaaatt agacagagag aatcagatat caccaaggag agaattcaga 850

 agatcctggc aactggtgcc aatgttattc taaccactgg tggaattgat 900

 gatatgtgtc tgaagtattt tgtggaggct ggtgctatgg cagttagaag 950

 agttttaaaa agggacctta aacgcattgc caaagcttct ggagcaacta 1000

 ttctgtcaac cctggccaat ttggaaggtg aagaaacttt tgaagctgca 1050

 atgttgggac aggcagaaga agtggtacag gagagaattt gtgatgatga 1100

 gctgatctta atcaaaaata ctaaggctcg tacgtctgca tcgattatct 1150

 tacgtggggc aaatgatttc atgtgtgatg agatggagcg ctctttacat 1200

 gatgcacttt gtgtagtgaa gagagttttg gagtcaaaat ctgtggttcc 1250

 cggtgggggt gctgtagaag cagccctttc catatacctt gaaaactatg 1300

 caaccagcat ggggtctcgg gaacagcttg cgattgcaga gtttgcaaga 1350

 tcacttcttg ttattcccaa tacactagca gttaatgctg cccaggactc 1400

 cacagatctg gttgcaaaat taagagcttt tcataatgag gcccaggtta 1450

 acccagaacg taaaaatcta aaatggattg gtcttgattt gagcaatggt 1500

 aaacctcgag acaacaaaca agcaggggtg tttgaaccaa ccatagttaa 1550

 agttaagagt ttgaaatttg caacagaagc tgcaatcacc attcttcgaa 1600

 ttgatgatct tattaaatta catccagaaa tccttcggat taaacatgga 1650

 agttatgaag atgctgttca ctctggagcc cttaatgatt gatctgatgt 1700

 tccttttatt tataacaatg ttaaatgcaa tgtcttgtac cttgagttga 1750

 gtattacaca ttaaagtaaa gtacaagctg taaacttggg tttttgtgat 1800

 gtaggaaatg gtttccatct gtactttggt cctctgattt cagatattgc 1850

 aacctagtac tttattagtt taaaaagaaa ttgaggttgt tcaaagttta 1900

 agcaattcat tctctctgaa cacacattgc tattcccatc ccacccccaa 1950

 tgcacagggc tgcaacacca cgacttctgc ccattctctc cagtgtgtgt 2000

 aacagggtca caagaattc 2019

<210> 1824
<211> 556
<212> PRT
<213> Homo sapien

<400> 1824
 Met Glu Gly Pro Leu Ser Val Phe Gly Asp Arg Ser Thr Gly Glu
   1               5                  10                  15

 Thr Ile Arg Ser Gln Asn Val Met Ala Ala Ala Ser Ile Ala Asn
                  20                  25                  30

 Ile Val Lys Ser Ser Leu Gly Pro Val Gly Leu Asp Lys Met Leu
                  35                  40                  45

 Val Asp Asp Ile Gly Asp Val Thr Ile Thr Asn Asp Gly Ala Thr
                  50                  55                  60

 Ile Leu Lys Leu Leu Glu Val Glu His Pro Ala Ala Lys Val Leu
                  65                  70                  75

 Cys Glu Leu Ala Asp Leu Gln Asp Lys Glu Val Gly Asp Gly Thr
                  80                  85                  90

 Thr Ser Val Val Ile Ile Ala Ala Glu Leu Leu Lys Asn Ala Asp
                  95                 100                 105

 Glu Leu Val Lys Gln Lys Ile His Pro Thr Ser Val Ile Ser Gly
                 110                 115                 120

 Tyr Arg Leu Ala Cys Lys Glu Ala Val Arg Tyr Ile Asn Glu Asn
                 125                 130                 135

 Leu Ile Val Asn Thr Asp Glu Leu Gly Arg Asp Cys Leu Ile Asn
                 140                 145                 150

 Ala Ala Lys Thr Ser Met Ser Ser Lys Ile Ile Gly Ile Asn Gly
                 155                 160                 165

 Asp Phe Phe Ala Asn Met Val Val Asp Ala Val Leu Ala Ile Lys
                 170                 175                 180

 Tyr Thr Asp Ile Arg Gly Gln Pro Arg Tyr Pro Val Asn Ser Val
                 185                 190                 195

 Asn Ile Leu Lys Ala His Gly Arg Ser Gln Met Glu Ser Met Leu
                 200                 205                 210

 Ile Ser Gly Tyr Ala Leu Asn Cys Val Val Gly Ser Gln Gly Met
                 215                 220                 225

 Pro Lys Arg Ile Val Asn Ala Lys Ile Ala Cys Leu Asp Phe Ser
                 230                 235                 240

 Leu Gln Lys Thr Lys Met Lys Leu Gly Val Gln Val Val Ile Thr
                 245                 250                 255

 Asp Pro Glu Lys Leu Asp Gln Ile Arg Gln Arg Glu Ser Asp Ile
                 260                 265                 270

 Thr Lys Glu Arg Ile Gln Lys Ile Leu Ala Thr Gly Ala Asn Val
                 275                 280                 285

 Ile Leu Thr Thr Gly Gly Ile Asp Asp Met Cys Leu Lys Tyr Phe
                 290                 295                 300

 Val Glu Ala Gly Ala Met Ala Val Arg Arg Val Leu Lys Arg Asp
                 305                 310                 315

 Leu Lys Arg Ile Ala Lys Ala Ser Gly Ala Thr Ile Leu Ser Thr
                 320                 325                 330

 Leu Ala Asn Leu Glu Gly Glu Glu Thr Phe Glu Ala Ala Met Leu
                 335                 340                 345

 Gly Gln Ala Glu Glu Val Val Gln Glu Arg Ile Cys Asp Asp Glu
                 350                 355                 360

 Leu Ile Leu Ile Lys Asn Thr Lys Ala Arg Thr Ser Ala Ser Ile
                 365                 370                 375

 Ile Leu Arg Gly Ala Asn Asp Phe Met Cys Asp Glu Met Glu Arg
                 380                 385                 390

 Ser Leu His Asp Ala Leu Cys Val Val Lys Arg Val Leu Glu Ser
                 395                 400                 405

 Lys Ser Val Val Pro Gly Gly Gly Ala Val Glu Ala Ala Leu Ser
                 410                 415                 420

 Ile Tyr Leu Glu Asn Tyr Ala Thr Ser Met Gly Ser Arg Glu Gln
                 425                 430                 435

 Leu Ala Ile Ala Glu Phe Ala Arg Ser Leu Leu Val Ile Pro Asn
                 440                 445                 450

 Thr Leu Ala Val Asn Ala Ala Gln Asp Ser Thr Asp Leu Val Ala
                 455                 460                 465

 Lys Leu Arg Ala Phe His Asn Glu Ala Gln Val Asn Pro Glu Arg
                 470                 475                 480

 Lys Asn Leu Lys Trp Ile Gly Leu Asp Leu Ser Asn Gly Lys Pro
                 485                 490                 495

 Arg Asp Asn Lys Gln Ala Gly Val Phe Glu Pro Thr Ile Val Lys
                 500                 505                 510

 Val Lys Ser Leu Lys Phe Ala Thr Glu Ala Ala Ile Thr Ile Leu
                 515                 520                 525

 Arg Ile Asp Asp Leu Ile Lys Leu His Pro Glu Ile Leu Arg Ile
                 530                 535                 540

 Lys His Gly Ser Tyr Glu Asp Ala Val His Ser Gly Ala Leu Asn
                 545                 550                 555

 Asp


<210> 1825
<211> 1750
<212> DNA
<213> Homo sapien

<400> 1825
 gctttctttc cgtcgcagag agcatcggcc ggcgaccgtt ccggcggcca 50

 ttgcgaaaac ttccccacgg ctactgcgtc cacgtggcgg tggcgtgggg 100

 actccctgaa agcagagcgg cagggcgccc ggaagtcgtg agtcgagtct 150

 tcccgggcta atccatgccg ggttggaggc tgctgacgca ggtcggcgcc 200

 caggtgctgg gtcgactcgg ggacggcctg ggtgctgccc tgggcccggg 250

 gaacagaaca cacatctggc tttttgttag aggtcttcat ggaaagagtg 300

 gtacatggtg ggatgagcat ctttctgaag aaaatgtccc attcattaag 350

 cagttggtct ctgatgaaga taaagcccaa ttagcaagta aactgtgtcc 400

 tctgaaagat gaaccatggc ctatacatcc ttgggaacca ggttccttta 450

 gagttggtct tattgccttg aagctgggca tgatgccttt atggaccaag 500

 gatggtcaaa agcatgtggt cacattactt caggtacaag actgtcatgt 550

 cttaaaatat acgtcaaagg aaaactgtaa tggaaaaatg gcaaccctgt 600

 ctgtaggagg aaaaactgta tcacgttttc gtaaagctac atccatattg 650

 gaattttacc gggaacttgg attgccgccg aaacagacag ttaaaatctt 700

 taatataaca gataatgctg caattaaacc aggcactcct ctttatgctg 750

 ctcactttcg tccaggacag tatgtggatg tcacagccaa aactattggt 800

 aaaggttttc aaggtgtcat gaaaagatgg ggatttaaag gccagcctgc 850

 tacgcatggt caaacgaaaa cccacaggag acctggagct gttgcaactg 900

 gtgatattgg cagagtctgg cctggaacta aaatgcctgg aaaaatggga 950

 aacatataca ggacagaata tggactgaaa gtgtggagaa taaacacaaa 1000

 gcacaacata atctatgtaa atggctctgt acctggacat aaaaattgct 1050

 tagtaaaggt caaagattct aaactgcctg catataagga tctcggtaaa 1100

 aatctaccat tccctacata ttttcctgat ggagatgaag aggaactgcc 1150

 agaagatttg tatgatgaaa acgtgtgtca gcccggtgcg ccttctatta 1200

 catttgccta acatctttgg acgtggcaga accttacata ttctgtgagc 1250

 ttcgatgagc cagagtgata tcataaccac cagaaatcat actctccttt 1300

 cttagtcaca acaaaatcac acatgtcatc tttgtcaagg gcataaatat 1350

 atcattcata cccccattaa attttgttag aaaaattacc acattaaata 1400

 tatgagttaa gtagattgga tttgctgaaa ttggtgttgg gcatattagc 1450

 aaaatattct taatttgtgg actcgattct tttttactac atatttccca 1500

 agttatctta agatgtctgt aaatttaact tttattaaag ttttgtcaat 1550

 ctttgtgaaa tagtggttgt ggaacagtag aaaaccatat ggggactata 1600

 gtgcaaccta tttgggtaaa gaaaccattt gctaaaatgg agaaagtaaa 1650

 tagattttta tttaaattac agaaacatgt taaaggccgg acaaaggaaa 1700

 gacaataaaa tcataaatta tcggtcctgt ttaaaaaaaa aaaaaaaaaa 1750

<210> 1826
<211> 348
<212> PRT
<213> Homo sapien

<400> 1826
 Met Pro Gly Trp Arg Leu Leu Thr Gln Val Gly Ala Gln Val Leu
   1               5                  10                  15

 Gly Arg Leu Gly Asp Gly Leu Gly Ala Ala Leu Gly Pro Gly Asn
                  20                  25                  30

 Arg Thr His Ile Trp Leu Phe Val Arg Gly Leu His Gly Lys Ser
                  35                  40                  45

 Gly Thr Trp Trp Asp Glu His Leu Ser Glu Glu Asn Val Pro Phe
                  50                  55                  60

 Ile Lys Gln Leu Val Ser Asp Glu Asp Lys Ala Gln Leu Ala Ser
                  65                  70                  75

 Lys Leu Cys Pro Leu Lys Asp Glu Pro Trp Pro Ile His Pro Trp
                  80                  85                  90

 Glu Pro Gly Ser Phe Arg Val Gly Leu Ile Ala Leu Lys Leu Gly
                  95                 100                 105

 Met Met Pro Leu Trp Thr Lys Asp Gly Gln Lys His Val Val Thr
                 110                 115                 120

 Leu Leu Gln Val Gln Asp Cys His Val Leu Lys Tyr Thr Ser Lys
                 125                 130                 135

 Glu Asn Cys Asn Gly Lys Met Ala Thr Leu Ser Val Gly Gly Lys
                 140                 145                 150

 Thr Val Ser Arg Phe Arg Lys Ala Thr Ser Ile Leu Glu Phe Tyr
                 155                 160                 165

 Arg Glu Leu Gly Leu Pro Pro Lys Gln Thr Val Lys Ile Phe Asn
                 170                 175                 180

 Ile Thr Asp Asn Ala Ala Ile Lys Pro Gly Thr Pro Leu Tyr Ala
                 185                 190                 195

 Ala His Phe Arg Pro Gly Gln Tyr Val Asp Val Thr Ala Lys Thr
                 200                 205                 210

 Ile Gly Lys Gly Phe Gln Gly Val Met Lys Arg Trp Gly Phe Lys
                 215                 220                 225

 Gly Gln Pro Ala Thr His Gly Gln Thr Lys Thr His Arg Arg Pro
                 230                 235                 240

 Gly Ala Val Ala Thr Gly Asp Ile Gly Arg Val Trp Pro Gly Thr
                 245                 250                 255

 Lys Met Pro Gly Lys Met Gly Asn Ile Tyr Arg Thr Glu Tyr Gly
                 260                 265                 270

 Leu Lys Val Trp Arg Ile Asn Thr Lys His Asn Ile Ile Tyr Val
                 275                 280                 285

 Asn Gly Ser Val Pro Gly His Lys Asn Cys Leu Val Lys Val Lys
                 290                 295                 300

 Asp Ser Lys Leu Pro Ala Tyr Lys Asp Leu Gly Lys Asn Leu Pro
                 305                 310                 315

 Phe Pro Thr Tyr Phe Pro Asp Gly Asp Glu Glu Glu Leu Pro Glu
                 320                 325                 330

 Asp Leu Tyr Asp Glu Asn Val Cys Gln Pro Gly Ala Pro Ser Ile
                 335                 340                 345

 Thr Phe Ala


<210> 1827
<211> 1676
<212> DNA
<213> Homo sapien

<400> 1827
 gaattccgcc gctgaccgag gcgtgcaaag actccagaat tggaggcatg 50

 atgaagactc tgctgctgtt tgtggggctg ctgctgacct gggagagtgg 100

 gcaggtcctg ggggaccaga cggtctcaga caatgagctc caggaaatgt 150

 ccaatcaggg aagtaagtac gtcaataagg aaattcaaaa tgctgtcaac 200

 ggggtgaaac agataaagac tctcatagaa aaaacaaacg aagagcgcaa 250

 gacactgctc agcaacctag aagaagccaa gaagaagaaa gaggatgccc 300

 taaatgagac cagggaatca gagacaaagc tgaaggagct cccaggagtg 350

 tgcaatgaga ccatgatggc cctctgggaa gagtgtaagc cctgcctgaa 400

 acagacctgc atgaagttct acgcacgcgt ctgcagaagt ggctcaggcc 450

 tggttggccg ccagcttgag gagttcctga accagagctc gcccttctac 500

 ttctggatga atggtgaccg catcgactcc ctgctggaga acgaccggca 550

 gcagacgcac atgctggatg tcatgcagga ccacttcagc cgcgcgtcca 600

 gcatcataga cgagctcttc caggacaggt tcttcacccg ggagccccag 650

 gatacctacc actacctgcc cttcagcctg ccccaccgga ggcctcactt 700

 cttctttccc aagtcccgca tcgtccgcag cttgatgccc ttctctccgt 750

 acgagcccct gaacttccac gccatgttcc agcccttcct tgagatgata 800

 cacgaggctc agcaggccat ggacatccac ttccacagcc cggccttcca 850

 gcacccgcca acagaattca tacgagaagg cgacgatgac cggactgtgt 900

 gccgggagat ccgccacaac tccacgggct gcctgcggat gaaggaccag 950

 tgtgacaagt gccgggagat cttgtctgtg gactgttcca ccaacaaccc 1000

 ctcccaggct aagctgcggc gggagctcga cgaatccctc caggtcgctg 1050

 agaggttgac caggaaatac aacgagctgc taaagtccta ccagtggaag 1100

 atgctcaaca cctcctcctt gctggagcag ctgaacgagc agtttaactg 1150

 ggtgtcccgg ctggcaaacc tcacgcaagg cgaagaccag tactatctgc 1200

 gggtcaccac ggtggcttcc cacacttctg actcggacgt tccttccggt 1250

 gtcactgagg tggtcgtgaa gctctttgac tctgatccca tcactgtgac 1300

 ggtccctgta gaagtctcca ggaagaaccc taaatttatg gagaccgtgg 1350

 cggagaaagc gctgcaggaa taccgcaaaa agcaccggga ggagtgagat 1400

 gtggatgttg cttttgcacc ttacgggggc atcttgagtc cagctccccc 1450

 caagatgagc tgcagccccc cagagagagc tctgcacgtc accaagtaac 1500

 caggccccag cctccaggcc cccaactccg cccagcctct ccccgctctg 1550

 gatcctgcac tctaacactc gactctgctg ctcatgggaa gaacagaatt 1600

 gctcctgcat gcaactaatt caataaaact gtcttgtgag ctgaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaag gaattc 1676

<210> 1828
<211> 449
<212> PRT
<213> Homo sapien

<400> 1828
 Met Met Lys Thr Leu Leu Leu Phe Val Gly Leu Leu Leu Thr Trp
   1               5                  10                  15

 Glu Ser Gly Gln Val Leu Gly Asp Gln Thr Val Ser Asp Asn Glu
                  20                  25                  30

 Leu Gln Glu Met Ser Asn Gln Gly Ser Lys Tyr Val Asn Lys Glu
                  35                  40                  45

 Ile Gln Asn Ala Val Asn Gly Val Lys Gln Ile Lys Thr Leu Ile
                  50                  55                  60

 Glu Lys Thr Asn Glu Glu Arg Lys Thr Leu Leu Ser Asn Leu Glu
                  65                  70                  75

 Glu Ala Lys Lys Lys Lys Glu Asp Ala Leu Asn Glu Thr Arg Glu
                  80                  85                  90

 Ser Glu Thr Lys Leu Lys Glu Leu Pro Gly Val Cys Asn Glu Thr
                  95                 100                 105

 Met Met Ala Leu Trp Glu Glu Cys Lys Pro Cys Leu Lys Gln Thr
                 110                 115                 120

 Cys Met Lys Phe Tyr Ala Arg Val Cys Arg Ser Gly Ser Gly Leu
                 125                 130                 135

 Val Gly Arg Gln Leu Glu Glu Phe Leu Asn Gln Ser Ser Pro Phe
                 140                 145                 150

 Tyr Phe Trp Met Asn Gly Asp Arg Ile Asp Ser Leu Leu Glu Asn
                 155                 160                 165

 Asp Arg Gln Gln Thr His Met Leu Asp Val Met Gln Asp His Phe
                 170                 175                 180

 Ser Arg Ala Ser Ser Ile Ile Asp Glu Leu Phe Gln Asp Arg Phe
                 185                 190                 195

 Phe Thr Arg Glu Pro Gln Asp Thr Tyr His Tyr Leu Pro Phe Ser
                 200                 205                 210

 Leu Pro His Arg Arg Pro His Phe Phe Phe Pro Lys Ser Arg Ile
                 215                 220                 225

 Val Arg Ser Leu Met Pro Phe Ser Pro Tyr Glu Pro Leu Asn Phe
                 230                 235                 240

 His Ala Met Phe Gln Pro Phe Leu Glu Met Ile His Glu Ala Gln
                 245                 250                 255

 Gln Ala Met Asp Ile His Phe His Ser Pro Ala Phe Gln His Pro
                 260                 265                 270

 Pro Thr Glu Phe Ile Arg Glu Gly Asp Asp Asp Arg Thr Val Cys
                 275                 280                 285

 Arg Glu Ile Arg His Asn Ser Thr Gly Cys Leu Arg Met Lys Asp
                 290                 295                 300

 Gln Cys Asp Lys Cys Arg Glu Ile Leu Ser Val Asp Cys Ser Thr
                 305                 310                 315

 Asn Asn Pro Ser Gln Ala Lys Leu Arg Arg Glu Leu Asp Glu Ser
                 320                 325                 330

 Leu Gln Val Ala Glu Arg Leu Thr Arg Lys Tyr Asn Glu Leu Leu
                 335                 340                 345

 Lys Ser Tyr Gln Trp Lys Met Leu Asn Thr Ser Ser Leu Leu Glu
                 350                 355                 360

 Gln Leu Asn Glu Gln Phe Asn Trp Val Ser Arg Leu Ala Asn Leu
                 365                 370                 375

 Thr Gln Gly Glu Asp Gln Tyr Tyr Leu Arg Val Thr Thr Val Ala
                 380                 385                 390

 Ser His Thr Ser Asp Ser Asp Val Pro Ser Gly Val Thr Glu Val
                 395                 400                 405

 Val Val Lys Leu Phe Asp Ser Asp Pro Ile Thr Val Thr Val Pro
                 410                 415                 420

 Val Glu Val Ser Arg Lys Asn Pro Lys Phe Met Glu Thr Val Ala
                 425                 430                 435

 Glu Lys Ala Leu Gln Glu Tyr Arg Lys Lys His Arg Glu Glu
                 440                 445

<210> 1829
<211> 4578
<212> DNA
<213> Homo sapien

<400> 1829
 tgcttgagct ctttgggcct ctgttttcac gtctgtatga tagaggtggt 50

 attgtttgac ttgtatttgt gaagtttcaa tgagattgat aattgtcgat 100

 tttatgttaa tccctagtac atggcctgct gtcaacaccc caggacaccc 150

 aggatatggt ctttgctgtt tgattttcct catccccagt ctcaagggga 200

 agccaggaca atgagaccag ccacttccca tcaggagtca ctgcaaggcc 250

 cccagggtgg ggtggtgggg agataagaac cgtgagagaa gttggcacaa 300

 aggagttatg ggacaaaggg tccaagatag gcagaaaaga aaatgttgcc 350

 agttgatggg gaagaaagga agtcggaggg ctcagacact gagggggaca 400

 gaacatctcc atgtgcagtc tcatctgcta ccctgaagga tctggaggta 450

 ggaggctctg ggcggaggtg cagtgacccc gcaggccagc cctccaacct 500

 cctcccgcag cggggactgg gtgcccctct gccagctgag acagcccaca 550

 cacaacccag ccctaatgat cgttctctct acctctcccc caagtcctcc 600

 tccgcctcct cctctctgca tgcgcgtcag agcccgtgcc aagaacaagc 650

 agcagtcctg aactcgaggt ccataaaaat cagtcgactg aatgacacca 700

 tcaaatcttt gaaacaacag aagaaacaag tggaacatca gctggaagaa 750

 gaaaagaaag caaacaatga gaaacagaaa gctgaaaggg agctagaggg 800

 tcaaatccag agattgaaca cagagaaaaa gaaactaaat acggacctgt 850

 atcacatgaa acattctctc agatactttg aagaagagtc caaggatctg 900

 gccggccgcc tgcaacgttc atcgcagcgt ataggagagt tagagtggtc 950

 tctctgtgct gtcgccgcca cacagaagaa gaagccggat gggttctcga 1000

 gccgcagtaa agcacttctc aagcggcagt tagagcagtc catacgggag 1050

 cagatactgc tgaaaggaca cgtgacacag ttgaaggagt cgcttaaaga 1100

 agtccagctg gagagagatc aatatgctga acaaataaaa ggagagaggg 1150

 cccagtggca gcagaggatg aggaaaatgt cgcaggaggt ttgcacattg 1200

 aaggaggaga agaagcatga tacgcatcgg gtagaggagc tggagaggag 1250

 cttgtccaga ctcaaaaacc agatggctga gccactgccc ccggatgccc 1300

 cagcagtgtc ctctgaggtg gagctgcaag acctgaggaa ggagctggag 1350

 agagtggcag gagagctcca ggctcaggtg gaaaacaatc agtgcatcag 1400

 tctcctgaac cgtgggcaaa aggagaggct tcgcgagcag gaggagaggc 1450

 ttcaggagca gcaggagagg cttcgggaac gggagaagag gcttcagcag 1500

 ctggccgagc cacagagcga cttggaggag ctgaagcacg agaacaagag 1550

 cgcactgcag ttggagcagc aagtaaagga gctgcaggag aagctgggcc 1600

 aggtgatgga gacgctcacc tcggccgaga aggagccaga ggcagcagtc 1650

 ccagcctcag ggactggggg cgagtctagc ggccttatgg acctcctgga 1700

 ggagaaggcg gacctgaggg agcatgtgga gaaactggaa cttggattca 1750

 tccagtaccg gagagagaga tgccatcaga acgtacatcg ccttctaaca 1800

 gagccagggg acagtgccaa agatgcgtca ccgggaggag gccatcatca 1850

 ggctggccca ggacaaggag gagaggaagg tgaagctgct ggagctgcag 1900

 gagatggtgt tgcggcttgt ggcagctaca acgaggggca cggcaaattc 1950

 ctggccgctg cccagaaccc tgctgctgaa cccagtccag gagccccagc 2000

 cccccaggag ctcggggctg ccgacaagca tggtgatctt tgtgaggcga 2050

 gcctcaccaa cagcgtggag cctgcacaag gagaagccag ggagggttct 2100

 tcccaggaca accctactgc acagccaatc gtgcagctcc ttggtgagat 2150

 gcaggaccac caggagcacc caggcttggg cagcaactgc tgtgtgccat 2200

 gcttttgctg ggcttggctg ccgagaagaa ggagataaac accaccatca 2250

 tcaaagagct gctcaagaaa tttttaaaaa cgaaacaaag ttatggggtt 2300

 aatctcctac acaattcatt tacttcattt gaatgttaga gctactcatg 2350

 attatttgtg tttctaattt atagtttaag tttatttgta aaaagttaaa 2400

 agagagtggg tctctgtggc tctcactgat gttcactctg gcatccttca 2450

 gcatttttct tttttcattt cataattgta ggtcattagc atgcatatcg 2500

 agtttgccct tacgtggtgg gagttcaaac acacaaagac ccactctttg 2550

 cacaaaactg ttctcgctgg tttggaatag gctcccgtgc ttttctaatg 2600

 ttattgcagc atggatgtcc attacagaat tcagataaaa tttgctaatg 2650

 ttctgctatg atgtttgatc tcatcttaat cacagtgagc tcttctatag 2700

 ctcaatatgc ggtttgccct caagtgtgca ctgtttatta ctttgtaata 2750

 tgccactgtg agtactgaca tttagagctg tttaaaggcc gagaactgga 2800

 aacagccttt cctccatttt ctgtgtattg gtgatgggag tgataacctt 2850

 ttgggggagc tttctaaatc tcacagaaga ggaaagtggc ctgctctggc 2900

 aggtatgtgc aggatacagt gtgtttcatc tgttccggtg ccaagaatga 2950

 gcagtgtact gtggcagttc cctttggatt tgtatgtgct ctgggctcat 3000

 gaagatattg catcgtgagc tgcagcagtt gcactctttt tcaatgacct 3050

 aaaaagggct tatttccgag gaatgaaagg ctgccatcat tggctgtggg 3100

 tgtgaaaaac ctttcctagc ttagagcatt tgtatctaca atacatttta 3150

 aagtcagagt tcgtgttccc tgttttaatc acatgactac ctgtcccagt 3200

 acacgaaagg gcgctggttg gcattcttct taatgtattt agtgaagatc 3250

 ataagaaatc ctttaagagt ttaaatgtct ctgaaacagg catacaggct 3300

 ctagtcaaga atgaattaga gtgaaggaaa gctgtgtgac acctggcatt 3350

 cctctctgtt catggagctt ctttgaggct tgaagtttga ttttactatc 3400

 tagacctctc tggctaatac ctattcttca accacctcgg ttactctgac 3450

 ataggaattt acttcttttc cttgagtgga aaacacttta gaaagtaata 3500

 acaaacatta ttataaacta atatatgtga gagtacttag ttgaaacaaa 3550

 aaggaatttt agtagacagt attatattat ctttgaaaat caaggagaag 3600

 tttatgcaac ttaaaatgtt tacacactgt ggtgcaatct actgtttgtg 3650

 aatgtctgta ttatcaggaa acatgtctat acgatcgcag agttgtattt 3700

 cctcacaaac ttctttacga agagtgaaat acgtttttgt acctctcatt 3750

 ttcagtcagg gacatacttt gtgcaatatt tctgtgattg tgcctatgca 3800

 tgatgaatga atgcatttca atcatacatt gcctaaatca taacttgatg 3850

 atgcttggga aagaatcaac agttaaaact tcatgaagtt ctaatgtctg 3900

 tgttccaaaa cacatcacat tattaggttg tagggagata tgtaggtgtg 3950

 ctccctgggg tggggagttt tctagttact agaccatctc catttttagc 4000

 acttggcagc ctcatgatcc ttttataaat gtgagattaa caggagagca 4050

 gcaatacgat tttgccaatg gaataacaga tttgccggca ttcactgaaa 4100

 gagggcagat attgggtcct tgtaacttca actgactctt ccaaattgta 4150

 tgaatttatc aatgtattac acaaatccag tttcagaatg ataaaaaatg 4200

 ttagaccaaa taatgcggct aattaacagt cgtatgattt ctagcccatg 4250

 ggtttaaaac tgtatcttaa agagtcattt taaaataata taaatattaa 4300

 aaaatgtaac tgctatctta atgttctgaa ataaaacatt ttaaaatata 4350

 aatcctgtag tttaaaagga agaaatggtg ggaaggaaaa gtagagaaag 4400

 aaatgccaat tacaggccaa agcgttattt gccaagtttt cttagaatga 4450

 attttaccaa tgtatgagtt cttgttaaca gaatgtgtaa cggaaatact 4500

 gaaagacttt tgcttaaagt ggcattattg actgctgatg tgatgctact 4550

 gtaatgcaat aaatttttaa attgttgc 4578

<210> 1830
<211> 631
<212> PRT
<213> Homo sapien

<400> 1830
 Met Leu Pro Val Asp Gly Glu Glu Arg Lys Ser Glu Gly Ser Asp
   1               5                  10                  15

 Thr Glu Gly Asp Arg Thr Ser Pro Cys Ala Val Ser Ser Ala Thr
                  20                  25                  30

 Leu Lys Asp Leu Glu Val Gly Gly Ser Gly Arg Arg Cys Ser Asp
                  35                  40                  45

 Pro Ala Gly Gln Pro Ser Asn Leu Leu Pro Gln Arg Gly Leu Gly
                  50                  55                  60

 Ala Pro Leu Pro Ala Glu Thr Ala His Thr Gln Pro Ser Pro Asn
                  65                  70                  75

 Asp Arg Ser Leu Tyr Leu Ser Pro Lys Ser Ser Ser Ala Ser Ser
                  80                  85                  90

 Ser Leu His Ala Arg Gln Ser Pro Cys Gln Glu Gln Ala Ala Val
                  95                 100                 105

 Leu Asn Ser Arg Ser Ile Lys Ile Ser Arg Leu Asn Asp Thr Ile
                 110                 115                 120

 Lys Ser Leu Lys Gln Gln Lys Lys Gln Val Glu His Gln Leu Glu
                 125                 130                 135

 Glu Glu Lys Lys Ala Asn Asn Glu Lys Gln Lys Ala Glu Arg Glu
                 140                 145                 150

 Leu Glu Gly Gln Ile Gln Arg Leu Asn Thr Glu Lys Lys Lys Leu
                 155                 160                 165

 Asn Thr Asp Leu Tyr His Met Lys His Ser Leu Arg Tyr Phe Glu
                 170                 175                 180

 Glu Glu Ser Lys Asp Leu Ala Gly Arg Leu Gln Arg Ser Ser Gln
                 185                 190                 195

 Arg Ile Gly Glu Leu Glu Trp Ser Leu Cys Ala Val Ala Ala Thr
                 200                 205                 210

 Gln Lys Lys Lys Pro Asp Gly Phe Ser Ser Arg Ser Lys Ala Leu
                 215                 220                 225

 Leu Lys Arg Gln Leu Glu Gln Ser Ile Arg Glu Gln Ile Leu Leu
                 230                 235                 240

 Lys Gly His Val Thr Gln Leu Lys Glu Ser Leu Lys Glu Val Gln
                 245                 250                 255

 Leu Glu Arg Asp Gln Tyr Ala Glu Gln Ile Lys Gly Glu Arg Ala
                 260                 265                 270

 Gln Trp Gln Gln Arg Met Arg Lys Met Ser Gln Glu Val Cys Thr
                 275                 280                 285

 Leu Lys Glu Glu Lys Lys His Asp Thr His Arg Val Glu Glu Leu
                 290                 295                 300

 Glu Arg Ser Leu Ser Arg Leu Lys Asn Gln Met Ala Glu Pro Leu
                 305                 310                 315

 Pro Pro Asp Ala Pro Ala Val Ser Ser Glu Val Glu Leu Gln Asp
                 320                 325                 330

 Leu Arg Lys Glu Leu Glu Arg Val Ala Gly Glu Leu Gln Ala Gln
                 335                 340                 345

 Val Glu Asn Asn Gln Cys Ile Ser Leu Leu Asn Arg Gly Gln Lys
                 350                 355                 360

 Glu Arg Leu Arg Glu Gln Glu Glu Arg Leu Gln Glu Gln Gln Glu
                 365                 370                 375

 Arg Leu Arg Glu Arg Glu Lys Arg Leu Gln Gln Leu Ala Glu Pro
                 380                 385                 390

 Gln Ser Asp Leu Glu Glu Leu Lys His Glu Asn Lys Ser Ala Leu
                 395                 400                 405

 Gln Leu Glu Gln Gln Val Lys Glu Leu Gln Glu Lys Leu Gly Gln
                 410                 415                 420

 Val Met Glu Thr Leu Thr Ser Ala Glu Lys Glu Pro Glu Ala Ala
                 425                 430                 435

 Val Pro Ala Ser Gly Thr Gly Gly Glu Ser Ser Gly Leu Met Asp
                 440                 445                 450

 Leu Leu Glu Glu Lys Ala Asp Leu Arg Glu His Val Glu Lys Leu
                 455                 460                 465

 Glu Leu Gly Phe Ile Gln Tyr Arg Arg Glu Arg Cys His Gln Asn
                 470                 475                 480

 Val His Arg Leu Leu Thr Glu Pro Gly Asp Ser Ala Lys Asp Ala
                 485                 490                 495

 Ser Pro Gly Gly Gly His His Gln Ala Gly Pro Gly Gln Gly Gly
                 500                 505                 510

 Glu Glu Gly Glu Ala Ala Gly Ala Ala Gly Asp Gly Val Ala Ala
                 515                 520                 525

 Cys Gly Ser Tyr Asn Glu Gly His Gly Lys Phe Leu Ala Ala Ala
                 530                 535                 540

 Gln Asn Pro Ala Ala Glu Pro Ser Pro Gly Ala Pro Ala Pro Gln
                 545                 550                 555

 Glu Leu Gly Ala Ala Asp Lys His Gly Asp Leu Cys Glu Ala Ser
                 560                 565                 570

 Leu Thr Asn Ser Val Glu Pro Ala Gln Gly Glu Ala Arg Glu Gly
                 575                 580                 585

 Ser Ser Gln Asp Asn Pro Thr Ala Gln Pro Ile Val Gln Leu Leu
                 590                 595                 600

 Gly Glu Met Gln Asp His Gln Glu His Pro Gly Leu Gly Ser Asn
                 605                 610                 615

 Cys Cys Val Pro Cys Phe Cys Trp Ala Trp Leu Pro Arg Arg Arg
                 620                 625                 630

 Arg


<210> 1831
<211> 1050
<212> DNA
<213> Homo sapien

<400> 1831
 ctttctgccc acactagaca tggcgcttgc cagcgtgttg gagagaccgc 50

 taccggtgaa ccagcgcggg tttttcggac ttgggggtcg tgcagatctg 100

 ctggatctag gtccagggag tctcagtgat ggtctgagcc tggccgcgcc 150

 aggctggggt gtcccagaag agccaggaat cgaaatgctt catggaacaa 200

 ccaccctggc cttcaagttc cgccatggag tcatagttgc agctgactcc 250

 agggctacag cgggtgctta cattgcctcc cagacggtga agaaggtgat 300

 agagatcaac ccatacctgc taggcaccat ggctgggggc gcagcggatt 350

 gcagcttctg ggaacggctg ttggctcggc aatgtcgaat ctatgagctt 400

 cgaaataagg aacgcatctc tgtagcagct gcctccaaac tgcttgccaa 450

 catggtgtat cagtacaaag gcatggggct gtccatgggc accatgatct 500

 gtggctggga taagagaggc cctggcctct actacgtgga cagtgaaggg 550

 aaccggattt caggggccac cttctctgta ggttctggct ctgtgtatgc 600

 atatggggtc atggatcggg gctattccta tgacctggaa gtggagcagg 650

 cctatgatct ggcccgtcga gccatctacc aagccaccta cagagatgcc 700

 tactcaggag gtgcagtcaa cctctaccac gtgcgggagg atggctggat 750

 ccgagtctcc agtgacaatg tggctgatct acatgagaag tatagtggct 800

 ctaccccctg aaagagggtg gatgcagctg cttgtgtttc ttggggtgac 850

 tgtcattggt aatacggaca cagtgaccca tcctccatcc tatttatagt 900

 ggaagggcct tcaattgtat cagtactttt ttttaagctc tggcacattg 950

 acctctatgt gttaccagtc attaatgagc tgctgcagag gtgactattt 1000

 gttttacttt cttggatgtt aaacattaca ctactcacta ctcaatctca 1050

<210> 1832
<211> 263
<212> PRT
<213> Homo sapien

<400> 1832
 Met Ala Leu Ala Ser Val Leu Glu Arg Pro Leu Pro Val Asn Gln
   1               5                  10                  15

 Arg Gly Phe Phe Gly Leu Gly Gly Arg Ala Asp Leu Leu Asp Leu
                  20                  25                  30

 Gly Pro Gly Ser Leu Ser Asp Gly Leu Ser Leu Ala Ala Pro Gly
                  35                  40                  45

 Trp Gly Val Pro Glu Glu Pro Gly Ile Glu Met Leu His Gly Thr
                  50                  55                  60

 Thr Thr Leu Ala Phe Lys Phe Arg His Gly Val Ile Val Ala Ala
                  65                  70                  75

 Asp Ser Arg Ala Thr Ala Gly Ala Tyr Ile Ala Ser Gln Thr Val
                  80                  85                  90

 Lys Lys Val Ile Glu Ile Asn Pro Tyr Leu Leu Gly Thr Met Ala
                  95                 100                 105

 Gly Gly Ala Ala Asp Cys Ser Phe Trp Glu Arg Leu Leu Ala Arg
                 110                 115                 120

 Gln Cys Arg Ile Tyr Glu Leu Arg Asn Lys Glu Arg Ile Ser Val
                 125                 130                 135

 Ala Ala Ala Ser Lys Leu Leu Ala Asn Met Val Tyr Gln Tyr Lys
                 140                 145                 150

 Gly Met Gly Leu Ser Met Gly Thr Met Ile Cys Gly Trp Asp Lys
                 155                 160                 165

 Arg Gly Pro Gly Leu Tyr Tyr Val Asp Ser Glu Gly Asn Arg Ile
                 170                 175                 180

 Ser Gly Ala Thr Phe Ser Val Gly Ser Gly Ser Val Tyr Ala Tyr
                 185                 190                 195

 Gly Val Met Asp Arg Gly Tyr Ser Tyr Asp Leu Glu Val Glu Gln
                 200                 205                 210

 Ala Tyr Asp Leu Ala Arg Arg Ala Ile Tyr Gln Ala Thr Tyr Arg
                 215                 220                 225

 Asp Ala Tyr Ser Gly Gly Ala Val Asn Leu Tyr His Val Arg Glu
                 230                 235                 240

 Asp Gly Trp Ile Arg Val Ser Ser Asp Asn Val Ala Asp Leu His
                 245                 250                 255

 Glu Lys Tyr Ser Gly Ser Thr Pro
                 260

<210> 1833
<211> 7711
<212> DNA
<213> Homo sapien

<400> 1833
 agggccccag gtctgtgggg catcctgtct tcctttatgt ggggtaactc 50

 tccgttccgt tccccaagcc ttcacagagt gacaccttca cagataatgg 100

 ggtggggggc ctggggtcct ctggcagaga catctgggga gaaagccagg 150

 gacctatccc tgctgaagca ggtacaggcc atcctctgga tttgtgggcc 200

 tgagagtgtg tgtgggtgtg ggtgcgcgcg tgcgcgcgcg tgcttttgag 250

 aaggcatatg ctgggtgtgt ctgtctgtgc ctatatcttt gtttgggtct 300

 cccatactgc gtatagatga atgggtcagg atatctggaa caaaatatgg 350

 aggtgaaggg tgagatcggg aaacaaaggg tatggccccc tagttcccaa 400

 agggagcagg gagatgggaa tagaattgaa ggtaggtttt aggctacttg 450

 ggaggaggaa tatttaggta attgtggaga ctttctcctg tgtgatgaag 500

 gcggcagaca ctgtgatcct gtgggcaaga agtaaaaatg accagctgag 550

 gatttctttt cctccaggac tgtgttgggg tgacaggatg cctgataagg 600

 atgacattcg gctgctgccg tcagcattgg gtgtgaagaa gagaaaacga 650

 ggacccaaga agcagaagga gaacaagcca ggaaaacccc gaaaacgcaa 700

 gaagcgtgac agtgaggagg aatttggttc tgagcgagat gagtaccggg 750

 agaagtcaga gagtgggggc agtgaatatg gaaccggacc gggtcggaaa 800

 cgaagaagga agcaccgaga aaaaaaggag aagaagacaa agcggcggaa 850

 aaagggggag ggagatgggg ggcaaaagca agtggaacag aagtcatcag 900

 caactctgct tctgacctgg ggcctggagg atgtggagca tgtgttctct 950

 gaggaggatt accacacgct caccaactac aaagccttca gccagttcat 1000

 gaggccccta attgctaaga agaatcctaa gatcccaatg tctaagatga 1050

 tgaccatcct tggggccaaa tggagagagt tcagtgccaa caaccccttc 1100

 aaggggtcag cagctgctgt ggcggcaggc agcggcagca gcagcagcag 1150

 ctgtagctga gcaggtgtca gctgctgtct cgtcggccac ccccatagca 1200

 ccctccggac cccccgccct tccaccaccc cctgctgctg atatccagcc 1250

 cccacccatc cgaagagcca aaaccaaaga gggcaaaggt ccaggccata 1300

 agaggcggag taagagcccc cgagtgcctg atggacgcaa gaagcttcgg 1350

 ggaaagaaaa tggcaccact caaaataaaa ctagggcttc tgggtggcaa 1400

 gaggaagaaa ggaggctcgt atgtttttca gagcgacgaa ggtcctgaac 1450

 cagaggctga ggaatcagac ctggacagtg gcagtgtcca cagtgcctca 1500

 ggccggcctg atggccctgt ccgcaccaag aaactaaaga gaggccggcc 1550

 aggaaggaag aagaagaagg tcctgggctg tcctgcagtg gccggggagg 1600

 aggaggttga tggctacgag acggatcacc aggattactg tgaggtgtgc 1650

 cagcagggtg gggaaattat tctgtgtgac acctgccctc gtgcctacca 1700

 cctcgtctgc cttgatcctg agcttgaccg ggctccagag ggcaaatgga 1750

 gctgccctca ctgtgagaag gagggggtcc agtgggaggc caaggaggaa 1800

 gaagaagaat acgaagagga gggagaggaa gaacgggaga aggaggagga 1850

 ggatgatcac atggagtact gccgcgtatg caaggacggc ggggagctcc 1900

 tgtgctgtga cgcgtgcatc tcctcctacc acattcattg tctaaaccct 1950

 cccctgcctg acattcccaa tggtgaatgg ctgtgtcccc gatgcacatg 2000

 ccccgtgctg aagggtcgag tgcagaagat cctacattgg cggtgggggg 2050

 agccacctgt agcagtgcca gcccctcaac aggcagatgg aaatccagat 2100

 gtcccacccc cccgtcctct tcaaggcaga tcagagcgag agttctttgt 2150

 caagtgggta ggactatcct actggcactg ctcctgggcc aaggagcttc 2200

 agctggaaat cttccatttg gttatgtatc gaaactacca gcggaagaat 2250

 gacatggatg agcccccacc cctggactat ggctccggcg aggatgatgg 2300

 gaagagcgac aagcgtaaag tgaaagaccc gcactatgct gagatggagg 2350

 agaagtacta tcgttttggc atcaagccag agtggatgac cgtccaccgc 2400

 atcatcaacc acagtgtgga taaaaagggg aattaccact atctagtaaa 2450

 atggagggac ttaccatatg accagtccac gtgggaggaa gatgaaatga 2500

 atatccctga atacgaagaa cataagcaaa gctactggag acaccgagaa 2550

 ctaattatgg gggaagaccc tgcccagccc cgcaagtata agaagaagaa 2600

 gaaggagcta cagggtgatg ggcctcccag ttctcccact aatgatccta 2650

 ccgtgaaata tgagactcag ccacggttta tcacagccac tggaggcacc 2700

 ctgcacatgt atcagttgga agggctgaac tggctacgct tctcctgggc 2750

 ccagggcact gacaccattc tcgctgatga gatggggcta ggcaagacca 2800

 tacaaaccat cgtcttcctc tactcactct acaaggaggg ccacacaaaa 2850

 ggtcccttcc tggtgagtgc cccactctct accatcatta actgggagcg 2900

 ggagttccag atgtgggcac ccaaattcta tgtggtgaca tacacgggtg 2950

 acaaggacag ccgggccatc attcgtgaga atgaattctc ctttgaggac 3000

 aatgccatca aagggggcaa gaaagctttt aagatgaaga gggaggcaca 3050

 ggtgaagttc catgttctcc tgacatcgta tgagctgatc accattgatc 3100

 aggcagcact tggttccatc cgctgggcct gtcttgtggt agatgaggcc 3150

 catcgactca agaacaacca gtccaagttt ttcagggttc tcaatggtta 3200

 caagatagat cataagttgc tgctgacagg aaccccattg cagaataatc 3250

 tggaggagct cttccatctc ctgaacttcc tcaccccaga gagatttaac 3300

 aacttggagg gcttcctgga ggagtttgct gacatatcca aagaggacca 3350

 gatcaagaaa ctgcatgatt tgctggggcc acacatgctg cggagactca 3400

 aggcagatgt ctttaagaac atgccagcca agacagagct catcgttcgg 3450

 gtggagctaa gccccatgca gaagaaatac tacaaataca tcctgactcg 3500

 aaattttgag gccttgaatt cacgaggtgg tgggaaccag gtgtcgctgc 3550

 ttaatatcat gatggatctt aagaagtgct gcaaccatcc ataccttttt 3600

 cccgtggctg ctatggagtc ccccaaactc cccagtgggg cttatgaggg 3650

 tggggcactt attaagtcgt ctgggaagct catgctgctc cagaagatgc 3700

 tgcgaaagct gaaggagcaa ggacaccgag tgctcatctt ctcgcagatg 3750

 accaaaatgt tagacttgct tgaggacttc ttagactatg aaggctacaa 3800

 gtatgagcgc atcgatggtg gtatcacggg tgccctgagg caggaggcca 3850

 tcgatcggtt taatgctcct ggggcccaac aattctgctt cctcctgtcc 3900

 acccgagctg ggggcctggg catcaatctg gccactgctg acactgtcat 3950

 catctttgat tctgactgga acccccataa tgacatccag gcctttagcc 4000

 gggctcatcg gattggccag gccaacaaag tgatgattta ccggtttgtg 4050

 actcgcgcgt cagtggaaga gcgaatcaca caagtggcca agagaaagat 4100

 gatgctgaca cacctggttg tgcggcctgg gctgggctcc aaggcaggct 4150

 ccatgtccaa gcaggagctt gacgacattc tcaaatttgg cactgaagag 4200

 ctattcaagg atgaaaacga gggggagaac aaggaggagg acagcagtgt 4250

 gattcattat gacaatgagg ccatcgctcg gctgttggac cggaaccagg 4300

 atgcaactga ggacactgac gtgcagaaca tgaatgagta tctcagctcc 4350

 ttcaaggtgg cacagtacgt cgtgcgggaa gaagacaaga ttgaggaaat 4400

 tgagcgagag atcatcaagc aggaggagaa tgtggaccct gactactggg 4450

 agaagctgct gaggcatcac tatgagcaac agcaggaaga cctagcccgg 4500

 aatctaggca agggcaagcg ggttcgcaag caagttaact acaatgatgc 4550

 tgctcaggaa gaccaagaca accagtcaga gtactcggtg ggttcagagg 4600

 aggaggatga agacttcgat gaacgtcctg aagggcgtag acagtcaaag 4650

 aggcagctcc ggaatgagaa agataagcca ctgcctccac tgctggcccg 4700

 agtcgggggc aacattgagg tgctgggctt caacacccgt cagcggaagg 4750

 ctttcctcaa tgctgtgatg cgctggggga tgccaccaca ggatgccttc 4800

 accacacagt ggctggtgcg ggacctgagg ggcaagactg agaaggagtt 4850

 taaggcctat gtgtctttgt tcatgcgcca tctgtgtgag cctggggcag 4900

 acggctctga aacctttgcc gatggggtcc ctcgggaggg actgagtcgc 4950

 cagcaggtgt tgacccgcat tggagtcatg tctctcgtca aaaagaaggt 5000

 gcaggagttt gagcacatca atgggcgttg gtcaatgccg gaactgatgc 5050

 ctgaccccag cgccgattct aagcgctcct ccagagcctc ctctcctacc 5100

 aaaacgtctc ccaccactcc tgaggcttct gctaccaaca gtccctgcac 5150

 ctctaaacct gctactccag ctccaagtga gaaaggagaa ggcataagga 5200

 cacctcttga gaaggaggaa gctgaaaacc aggaggaaaa gccagagaag 5250

 aacagcagaa ttggggagaa gatggagaca gaggctgatg cccccagccc 5300

 agccccatca cttggggagc ggctggagcc aaggaagatt cctctagagg 5350

 atgaggtgcc aggggtgcct ggagagatgg agcctgaacc tgggtaccgt 5400

 ggggacagag agaagtcagc cacagagtcg acgccaggag aaagggggga 5450

 ggagaagccg ttggatggac aggaacacag ggagaggccg gagggggaaa 5500

 caggggattt gggcaagaga gaagatgtaa aaggtgaccg ggagcttcga 5550

 ccagggcctc gagatgagcc acggtccaat gggcgacgag aggaaaagac 5600

 agagaagccc cggttcatgt tcaatatcgc cgatggtggc ttcacagagc 5650

 ttcacacact gtggcagaat gaggaacggg cagctatttc ctcggggaaa 5700

 ctcaatgaga tctggcacag aagacatgac tattggcttc tggctgggat 5750

 tgtcctccat ggctatgcac ggtggcagga catccagaat gatgctcaat 5800

 ttgccattat caacgagcca tttaaaactg aagccaataa ggggaacttt 5850

 ctggagatga aaaataagtt cctggcccgg aggttcaagc tcctggagca 5900

 ggcgctggtg attgaggagc agctgcggcg ggcggcctac ctgaacctgt 5950

 cgcaggagcc ggcgcacccc gccatggccc tccacgcccg cttcgccgag 6000

 gccgagtgcc tggccgagag ccaccagcac ctctccaagg agtcgctggc 6050

 ggggaacaag ccggccaacg ccgtcctgca caaggttctg aaccagctgg 6100

 aggagttgct gagcgacatg aaggcggacg tgacccgcct gccagccacg 6150

 ctgtcccgaa taccccccat cgcagcccgc cttcagatgt ccgagcgcag 6200

 catcctcagc cggctggcca gcaagggcac ggagcctcac cccacaccgg 6250

 cctacccgcc gggtccctac gctacacctc cggggtacgg ggcggccttc 6300

 agcgccgcac ccgtaggggc cctggccgcc gcaggcgcca attacagcca 6350

 gatgcctgca gggtccttca tcacagccgc caccaacggc cctccagtgc 6400

 ttgtgaagaa ggagaaggaa atggtggggg cattggtgtc agacgggctg 6450

 gatcggaagg agccccgagc cggggaggtg atctgtatag acgactgact 6500

 ggatcccagg cctgcccttc acccaggccc cgtccccgag gccgaccccc 6550

 agctcaagcg ctggggcctg ctgccagccc tccaccttcc ccaccccttg 6600

 ggccatcact gggctaggaa cccctttgcc cctctctgca gctcctctct 6650

 tcaagaaggg ccctttgtct ttctccactc ccacacacct ttcccaccaa 6700

 gccttgaaga ctgtgctggt gagaagaagt ctgggtggga gatggctggc 6750

 agggtcttcc aagtaccttc ctcccacact gccaagtata cacaacttcc 6800

 cagtaaatgg ttgtggggag gaaagaggtg gagcctcccc agccgtttcc 6850

 ctgcagaatc agctctgtct catgtggaag tggagaatca gccttgcctg 6900

 gcctttagga acttttgtgg ggaagagagc tttgaagaga ggagggggac 6950

 tttagagagg gatgaaaatg agccctggga gggaggaagg gacgaggagg 7000

 ggtggctgca tgttaccgtc ccctacctct ccccacgtgg agggtggagc 7050

 agttatgagg gaggaagtca actgctgttc agcctcagaa taaaggtgcc 7100

 gttcactggc tcagttacct cctgtgtacc ggcatcttgt gttgggaatg 7150

 ttcccccctc cctagggacc aaggaccacc cctacaaaaa gagtaatggt 7200

 tgggtgatac tccctcaagc caaagaggag ctccccaacc tgttctaggg 7250

 acccaggtaa cctagaaggg tgggagagaa tacaatgggc cagatgtggt 7300

 ggaagcccag ctctggggct caggttcctg gaagacttct actaccctcc 7350

 ctcctcaagg cctggataca gactaaattt gtataagtca ggcaggggac 7400

 ctagtcaggg tcttgggagc taccttgtcg ttgggaccag agcaaaatag 7450

 tggagggcag gctagggaaa tgtgggcaca tcccccctcc caggaggggc 7500

 cggggagagt ggcagtttgc atggcgaacc ccccacttcc tctttgctgc 7550

 cccttcactt tcttgctgcc cctttcccag tctctcttca cacccactcc 7600

 tggtctgtcc tgatcccctc ttctgtatca ggtttattgg ttgtacatat 7650

 aaattatact ttcctttcaa aaaaaatcta tgtcgggtgc ggagaaagag 7700

 gtaatgaaat g 7711

<210> 1834
<211> 2001
<212> PRT
<213> Homo sapien

<400> 1834
 Met Lys Ala Ala Asp Thr Val Ile Leu Trp Ala Arg Ser Lys Asn
   1               5                  10                  15

 Asp Gln Leu Arg Ile Ser Phe Pro Pro Gly Leu Cys Trp Gly Asp
                  20                  25                  30

 Arg Met Pro Asp Lys Asp Asp Ile Arg Leu Leu Pro Ser Ala Leu
                  35                  40                  45

 Gly Val Lys Lys Arg Lys Arg Gly Pro Lys Lys Gln Lys Glu Asn
                  50                  55                  60

 Lys Pro Gly Lys Pro Arg Lys Arg Lys Lys Arg Asp Ser Glu Glu
                  65                  70                  75

 Glu Phe Gly Ser Glu Arg Asp Glu Tyr Arg Glu Lys Ser Glu Ser
                  80                  85                  90

 Gly Gly Ser Glu Tyr Gly Thr Gly Pro Gly Arg Lys Arg Arg Arg
                  95                 100                 105

 Lys His Arg Glu Lys Lys Glu Lys Lys Thr Lys Arg Arg Lys Lys
                 110                 115                 120

 Gly Glu Gly Asp Gly Gly Gln Lys Gln Val Glu Gln Lys Ser Ser
                 125                 130                 135

 Ala Thr Leu Leu Leu Thr Trp Gly Leu Glu Asp Val Glu His Val
                 140                 145                 150

 Phe Ser Glu Glu Asp Tyr His Thr Leu Thr Asn Tyr Lys Ala Phe
                 155                 160                 165

 Ser Gln Phe Met Arg Pro Leu Ile Ala Lys Lys Asn Pro Lys Ile
                 170                 175                 180

 Pro Met Ser Lys Met Met Thr Pro Ser Leu Gly Pro Asn Gly Glu
                 185                 190                 195

 Ser Ser Val Pro Thr Thr Pro Ser Arg Gly Gln Gln Leu Leu Trp
                 200                 205                 210

 Arg Gln Ala Ala Ala Ala Ala Ala Ala Ala Val Ala Glu Gln Val
                 215                 220                 225

 Ser Ala Ala Val Ser Ser Ala Thr Pro Ile Ala Pro Ser Gly Pro
                 230                 235                 240

 Pro Ala Leu Pro Pro Pro Pro Ala Ala Asp Ile Gln Pro Pro Pro
                 245                 250                 255

 Ile Arg Arg Ala Lys Thr Lys Glu Gly Lys Gly Pro Gly His Lys
                 260                 265                 270

 Arg Arg Ser Lys Ser Pro Arg Val Pro Asp Gly Arg Lys Lys Leu
                 275                 280                 285

 Arg Gly Lys Lys Met Ala Pro Leu Lys Ile Lys Leu Gly Leu Leu
                 290                 295                 300

 Gly Gly Lys Arg Lys Lys Gly Gly Ser Tyr Val Phe Gln Ser Asp
                 305                 310                 315

 Glu Gly Pro Glu Pro Glu Ala Glu Glu Ser Asp Leu Asp Ser Gly
                 320                 325                 330

 Ser Val His Ser Ala Ser Gly Arg Pro Asp Gly Pro Val Arg Thr
                 335                 340                 345

 Lys Lys Leu Lys Arg Gly Arg Pro Gly Arg Lys Lys Lys Lys Val
                 350                 355                 360

 Leu Gly Cys Pro Ala Val Ala Gly Glu Glu Glu Val Asp Gly Tyr
                 365                 370                 375

 Glu Thr Asp His Gln Asp Tyr Cys Glu Val Cys Gln Gln Gly Gly
                 380                 385                 390

 Glu Ile Ile Leu Cys Asp Thr Cys Pro Arg Ala Tyr His Leu Val
                 395                 400                 405

 Cys Leu Asp Pro Glu Leu Asp Arg Ala Pro Glu Gly Lys Trp Ser
                 410                 415                 420

 Cys Pro His Cys Glu Lys Glu Gly Val Gln Trp Glu Ala Lys Glu
                 425                 430                 435

 Glu Glu Glu Glu Tyr Glu Glu Glu Gly Glu Glu Glu Arg Glu Lys
                 440                 445                 450

 Glu Glu Glu Asp Asp His Met Glu Tyr Cys Arg Val Cys Lys Asp
                 455                 460                 465

 Gly Gly Glu Leu Leu Cys Cys Asp Ala Cys Ile Ser Ser Tyr His
                 470                 475                 480

 Ile His Cys Leu Asn Pro Pro Leu Pro Asp Ile Pro Asn Gly Glu
                 485                 490                 495

 Trp Leu Cys Pro Arg Cys Thr Cys Pro Val Leu Lys Gly Arg Val
                 500                 505                 510

 Gln Lys Ile Leu His Trp Arg Trp Gly Glu Pro Pro Val Ala Val
                 515                 520                 525

 Pro Ala Pro Gln Gln Ala Asp Gly Asn Pro Asp Val Pro Pro Pro
                 530                 535                 540

 Arg Pro Leu Gln Gly Arg Ser Glu Arg Glu Phe Phe Val Lys Trp
                 545                 550                 555

 Val Gly Leu Ser Tyr Trp His Cys Ser Trp Ala Lys Glu Leu Gln
                 560                 565                 570

 Leu Glu Ile Phe His Leu Val Met Tyr Arg Asn Tyr Gln Arg Lys
                 575                 580                 585

 Asn Asp Met Asp Glu Pro Pro Pro Leu Asp Tyr Gly Ser Gly Glu
                 590                 595                 600

 Asp Asp Gly Lys Ser Asp Lys Arg Lys Val Lys Asp Pro His Tyr
                 605                 610                 615

 Ala Glu Met Glu Glu Lys Tyr Tyr Arg Phe Gly Ile Lys Pro Glu
                 620                 625                 630

 Trp Met Thr Val His Arg Ile Ile Asn His Ser Val Asp Lys Lys
                 635                 640                 645

 Gly Asn Tyr His Tyr Leu Val Lys Trp Arg Asp Leu Pro Tyr Asp
                 650                 655                 660

 Gln Ser Thr Trp Glu Glu Asp Glu Met Asn Ile Pro Glu Tyr Glu
                 665                 670                 675

 Glu His Lys Gln Ser Tyr Trp Arg His Arg Glu Leu Ile Met Gly
                 680                 685                 690

 Glu Asp Pro Ala Gln Pro Arg Lys Tyr Lys Lys Lys Lys Lys Glu
                 695                 700                 705

 Leu Gln Gly Asp Gly Pro Pro Ser Ser Pro Thr Asn Asp Pro Thr
                 710                 715                 720

 Val Lys Tyr Glu Thr Gln Pro Arg Phe Ile Thr Ala Thr Gly Gly
                 725                 730                 735

 Thr Leu His Met Tyr Gln Leu Glu Gly Leu Asn Trp Leu Arg Phe
                 740                 745                 750

 Ser Trp Ala Gln Gly Thr Asp Thr Ile Leu Ala Asp Glu Met Gly
                 755                 760                 765

 Leu Gly Lys Thr Ile Gln Thr Ile Val Phe Leu Tyr Ser Leu Tyr
                 770                 775                 780

 Lys Glu Gly His Thr Lys Gly Pro Phe Leu Val Ser Ala Pro Leu
                 785                 790                 795

 Ser Thr Ile Ile Asn Trp Glu Arg Glu Phe Gln Met Trp Ala Pro
                 800                 805                 810

 Lys Phe Tyr Val Val Thr Tyr Thr Gly Asp Lys Asp Ser Arg Ala
                 815                 820                 825

 Ile Ile Arg Glu Asn Glu Phe Ser Phe Glu Asp Asn Ala Ile Lys
                 830                 835                 840

 Gly Gly Lys Lys Ala Phe Lys Met Lys Arg Glu Ala Gln Val Lys
                 845                 850                 855

 Phe His Val Leu Leu Thr Ser Tyr Glu Leu Ile Thr Ile Asp Gln
                 860                 865                 870

 Ala Ala Leu Gly Ser Ile Arg Trp Ala Cys Leu Val Val Asp Glu
                 875                 880                 885

 Ala His Arg Leu Lys Asn Asn Gln Ser Lys Phe Phe Arg Val Leu
                 890                 895                 900

 Asn Gly Tyr Lys Ile Asp His Lys Leu Leu Leu Thr Gly Thr Pro
                 905                 910                 915

 Leu Gln Asn Asn Leu Glu Glu Leu Phe His Leu Leu Asn Phe Leu
                 920                 925                 930

 Thr Pro Glu Arg Phe Asn Asn Leu Glu Gly Phe Leu Glu Glu Phe
                 935                 940                 945

 Ala Asp Ile Ser Lys Glu Asp Gln Ile Lys Lys Leu His Asp Leu
                 950                 955                 960

 Leu Gly Pro His Met Leu Arg Arg Leu Lys Ala Asp Val Phe Lys
                 965                 970                 975

 Asn Met Pro Ala Lys Thr Glu Leu Ile Val Arg Val Glu Leu Ser
                 980                 985                 990

 Pro Met Gln Lys Lys Tyr Tyr Lys Tyr Ile Leu Thr Arg Asn Phe
                 995                1000                1005

 Glu Ala Leu Asn Ser Arg Gly Gly Gly Asn Gln Val Ser Leu Leu
                1010                1015                1020

 Asn Ile Met Met Asp Leu Lys Lys Cys Cys Asn His Pro Tyr Leu
                1025                1030                1035

 Phe Pro Val Ala Ala Met Glu Ser Pro Lys Leu Pro Ser Gly Ala
                1040                1045                1050

 Tyr Glu Gly Gly Ala Leu Ile Lys Ser Ser Gly Lys Leu Met Leu
                1055                1060                1065

 Leu Gln Lys Met Leu Arg Lys Leu Lys Glu Gln Gly His Arg Val
                1070                1075                1080

 Leu Ile Phe Ser Gln Met Thr Lys Met Leu Asp Leu Leu Glu Asp
                1085                1090                1095

 Phe Leu Asp Tyr Glu Gly Tyr Lys Tyr Glu Arg Ile Asp Gly Gly
                1100                1105                1110

 Ile Thr Gly Ala Leu Arg Gln Glu Ala Ile Asp Arg Phe Asn Ala
                1115                1120                1125

 Pro Gly Ala Gln Gln Phe Cys Phe Leu Leu Ser Thr Arg Ala Gly
                1130                1135                1140

 Gly Leu Gly Ile Asn Leu Ala Thr Ala Asp Thr Val Ile Ile Phe
                1145                1150                1155

 Asp Ser Asp Trp Asn Pro His Asn Asp Ile Gln Ala Phe Ser Arg
                1160                1165                1170

 Ala His Arg Ile Gly Gln Ala Asn Lys Val Met Ile Tyr Arg Phe
                1175                1180                1185

 Val Thr Arg Ala Ser Val Glu Glu Arg Ile Thr Gln Val Ala Lys
                1190                1195                1200

 Arg Lys Met Met Leu Thr His Leu Val Val Arg Pro Gly Leu Gly
                1205                1210                1215

 Ser Lys Ala Gly Ser Met Ser Lys Gln Glu Leu Asp Asp Ile Leu
                1220                1225                1230

 Lys Phe Gly Thr Glu Glu Leu Phe Lys Asp Glu Asn Glu Gly Glu
                1235                1240                1245

 Asn Lys Glu Glu Asp Ser Ser Val Ile His Tyr Asp Asn Glu Ala
                1250                1255                1260

 Ile Ala Arg Leu Leu Asp Arg Asn Gln Asp Ala Thr Glu Asp Thr
                1265                1270                1275

 Asp Val Gln Asn Met Asn Glu Tyr Leu Ser Ser Phe Lys Val Ala
                1280                1285                1290

 Gln Tyr Val Val Arg Glu Glu Asp Lys Ile Glu Glu Ile Glu Arg
                1295                1300                1305

 Glu Ile Ile Lys Gln Glu Glu Asn Val Asp Pro Asp Tyr Trp Glu
                1310                1315                1320

 Lys Leu Leu Arg His His Tyr Glu Gln Gln Gln Glu Asp Leu Ala
                1325                1330                1335

 Arg Asn Leu Gly Lys Gly Lys Arg Val Arg Lys Gln Val Asn Tyr
                1340                1345                1350

 Asn Asp Ala Ala Gln Glu Asp Gln Asp Asn Gln Ser Glu Tyr Ser
                1355                1360                1365

 Val Gly Ser Glu Glu Glu Asp Glu Asp Phe Asp Glu Arg Pro Glu
                1370                1375                1380

 Gly Arg Arg Gln Ser Lys Arg Gln Leu Arg Asn Glu Lys Asp Lys
                1385                1390                1395

 Pro Leu Pro Pro Leu Leu Ala Arg Val Gly Gly Asn Ile Glu Val
                1400                1405                1410

 Leu Gly Phe Asn Thr Arg Gln Arg Lys Ala Phe Leu Asn Ala Val
                1415                1420                1425

 Met Arg Trp Gly Met Pro Pro Gln Asp Ala Phe Thr Thr Gln Trp
                1430                1435                1440

 Leu Val Arg Asp Leu Arg Gly Lys Thr Glu Lys Glu Phe Lys Ala
                1445                1450                1455

 Tyr Val Ser Leu Phe Met Arg His Leu Cys Glu Pro Gly Ala Asp
                1460                1465                1470

 Gly Ser Glu Thr Phe Ala Asp Gly Val Pro Arg Glu Gly Leu Ser
                1475                1480                1485

 Arg Gln Gln Val Leu Thr Arg Ile Gly Val Met Ser Leu Val Lys
                1490                1495                1500

 Lys Lys Val Gln Glu Phe Glu His Ile Asn Gly Arg Trp Ser Met
                1505                1510                1515

 Pro Glu Leu Met Pro Asp Pro Ser Ala Asp Ser Lys Arg Ser Ser
                1520                1525                1530

 Arg Ala Ser Ser Pro Thr Lys Thr Ser Pro Thr Thr Pro Glu Ala
                1535                1540                1545

 Ser Ala Thr Asn Ser Pro Cys Thr Ser Lys Pro Ala Thr Pro Ala
                1550                1555                1560

 Pro Ser Glu Lys Gly Glu Gly Ile Arg Thr Pro Leu Glu Lys Glu
                1565                1570                1575

 Glu Ala Glu Asn Gln Glu Glu Lys Pro Glu Lys Asn Ser Arg Ile
                1580                1585                1590

 Gly Glu Lys Met Glu Thr Glu Ala Asp Ala Pro Ser Pro Ala Pro
                1595                1600                1605

 Ser Leu Gly Glu Arg Leu Glu Pro Arg Lys Ile Pro Leu Glu Asp
                1610                1615                1620

 Glu Val Pro Gly Val Pro Gly Glu Met Glu Pro Glu Pro Gly Tyr
                1625                1630                1635

 Arg Gly Asp Arg Glu Lys Ser Ala Thr Glu Ser Thr Pro Gly Glu
                1640                1645                1650

 Arg Gly Glu Glu Lys Pro Leu Asp Gly Gln Glu His Arg Glu Arg
                1655                1660                1665

 Pro Glu Gly Glu Thr Gly Asp Leu Gly Lys Arg Glu Asp Val Lys
                1670                1675                1680

 Gly Asp Arg Glu Leu Arg Pro Gly Pro Arg Asp Glu Pro Arg Ser
                1685                1690                1695

 Asn Gly Arg Arg Glu Glu Lys Thr Glu Lys Pro Arg Phe Met Phe
                1700                1705                1710

 Asn Ile Ala Asp Gly Gly Phe Thr Glu Leu His Thr Leu Trp Gln
                1715                1720                1725

 Asn Glu Glu Arg Ala Ala Ile Ser Ser Gly Lys Leu Asn Glu Ile
                1730                1735                1740

 Trp His Arg Arg His Asp Tyr Trp Leu Leu Ala Gly Ile Val Leu
                1745                1750                1755

 His Gly Tyr Ala Arg Trp Gln Asp Ile Gln Asn Asp Ala Gln Phe
                1760                1765                1770

 Ala Ile Ile Asn Glu Pro Phe Lys Thr Glu Ala Asn Lys Gly Asn
                1775                1780                1785

 Phe Leu Glu Met Lys Asn Lys Phe Leu Ala Arg Arg Phe Lys Leu
                1790                1795                1800

 Leu Glu Gln Ala Leu Val Ile Glu Glu Gln Leu Arg Arg Ala Ala
                1805                1810                1815

 Tyr Leu Asn Leu Ser Gln Glu Pro Ala His Pro Ala Met Ala Leu
                1820                1825                1830

 His Ala Arg Phe Ala Glu Ala Glu Cys Leu Ala Glu Ser His Gln
                1835                1840                1845

 His Leu Ser Lys Glu Ser Leu Ala Gly Asn Lys Pro Ala Asn Ala
                1850                1855                1860

 Val Leu His Lys Val Leu Asn Gln Leu Glu Glu Leu Leu Ser Asp
                1865                1870                1875

 Met Lys Ala Asp Val Thr Arg Leu Pro Ala Thr Leu Ser Arg Ile
                1880                1885                1890

 Pro Pro Ile Ala Ala Arg Leu Gln Met Ser Glu Arg Ser Ile Leu
                1895                1900                1905

 Ser Arg Leu Ala Ser Lys Gly Thr Glu Pro His Pro Thr Pro Ala
                1910                1915                1920

 Tyr Pro Pro Gly Pro Tyr Ala Thr Pro Pro Gly Tyr Gly Ala Ala
                1925                1930                1935

 Phe Ser Ala Ala Pro Val Gly Ala Leu Ala Ala Ala Gly Ala Asn
                1940                1945                1950

 Tyr Ser Gln Met Pro Ala Gly Ser Phe Ile Thr Ala Ala Thr Asn
                1955                1960                1965

 Gly Pro Pro Val Leu Val Lys Lys Glu Lys Glu Met Val Gly Ala
                1970                1975                1980

 Leu Val Ser Asp Gly Leu Asp Arg Lys Glu Pro Arg Ala Gly Glu
                1985                1990                1995

 Val Ile Cys Ile Asp Asp
                2000

<210> 1835
<211> 1941
<212> DNA
<213> Homo sapien

<400> 1835
 tctcttgatt cctagtctct cgatatggca cctccgtcag tctttgccga 50

 ggttccgcag gcccagcctg tcctggtctt caagctcact gccgacttca 100

 gggaggatcc ggacccccgc aaggtcaacc tgggagtggg agcatatcgc 150

 acggatgact gccatccctg ggttttgcca gtagtgaaga aagtggagca 200

 gaagattgct aatgacaata gcctaaatca cgagtatctg ccaatcctgg 250

 gcctggctga gttccggagc tgtgcttctc gtcttgccct tggggatgac 300

 agcccagcac tcaaggagaa gcgggtagga ggtgtgcaat ctttgggggg 350

 aacaggtgca cttcgaattg gagctgattt cttagcgcgt tggtacaatg 400

 gaacaaacaa caagaacaca cctgtctatg tgtcctcacc aacctgggag 450

 aatcacaatg ctgtgttttc cgctgctggt tttaaagaca ttcggtccta 500

 tcgctactgg gatgcagaga agagaggatt ggacctccag ggcttcctga 550

 atgatctgga gaatgctcct gagttctcca ttgttgtcct ccacgcctgt 600

 gcacacaacc caactgggat tgacccaact ccggagcagt ggaagcagat 650

 tgcttctgtc atgaagcacc ggtttctgtt ccccttcttt gactcagcct 700

 atcagggctt cgcatctgga aacctggaga gagatgcctg ggccattcgc 750

 tattttgtgt ctgaaggctt cgagttcttc tgtgcccagt ccttctccaa 800

 gaacttcggg ctctacaatg agagagtcgg gaatctgact gtggttggaa 850

 aagaacctga gagcatcctg caagtccttt cccagatgga gaagatcgtg 900

 cggattactt ggtccaatcc ccccgcccag ggagcacgaa ttgtggccag 950

 caccctctct aaccctgagc tctttgagga atggacaggt aatgtgaaga 1000

 caatggctga ccggattctg accatgagat ctgaactcag ggcacgacta 1050

 gaagccctca aaacccctgg gacctggaac cacatcactg atcaaattgg 1100

 catgttcagc ttcactgggt tgaaccccaa gcaggttgag tatctggtca 1150

 atgaaaagca catctacctg ctgccaagtg gtcgaatcaa cgtgagtggc 1200

 ttaaccacca aaaatctaga ttacgtggcc acctccatcc atgaagcagt 1250

 caccaaaatc cagtgaagaa acaccacccg tccagtacca ccaaagtagt 1300

 tctctgtcat gtgtgttccc tgcctgcaca aacctacatg tacataccat 1350

 ggattagaga cacttgcagg actgaaagct gctctggtga ggcagcctct 1400

 gtttaaaccg gccccacatg aagagaacat cccttgagac gaatttggag 1450

 actgggatta gagcctttgg aggtcaaagc aaattaagat ttttatttaa 1500

 gaataaaaga gtactttgat catgagacat aggtatcttg tccctctcac 1550

 taaaaaggag tgttgtgtgt ggcggccacg tgcttctatg tggtgtttga 1600

 ctctgtacaa attctagtcc caaagatcaa gttgtctgaa ggagccaaag 1650

 tgtgaatgtg ggtgtcggct gcggcattaa attcatcatc tcaacccaga 1700

 gtgtctggtc tccctgctct ttctgcatgg ttgtgtccct agtcctaagc 1750

 tttggttctt tagggtgact gtggtaagaa ggatatttaa tcatgacatg 1800

 cacggacacg tacatattta actgaaacaa gttttaccaa acagtattta 1850

 ctcgtgatgt gcgtagtgca ttctgatatt tttgagccat tctattgtgt 1900

 tctacttcac ctaaaaaaat aaaataaaaa tgttgatcaa g 1941

<210> 1836
<211> 413
<212> PRT
<213> Homo sapien

<400> 1836
 Met Ala Pro Pro Ser Val Phe Ala Glu Val Pro Gln Ala Gln Pro
   1               5                  10                  15

 Val Leu Val Phe Lys Leu Thr Ala Asp Phe Arg Glu Asp Pro Asp
                  20                  25                  30

 Pro Arg Lys Val Asn Leu Gly Val Gly Ala Tyr Arg Thr Asp Asp
                  35                  40                  45

 Cys His Pro Trp Val Leu Pro Val Val Lys Lys Val Glu Gln Lys
                  50                  55                  60

 Ile Ala Asn Asp Asn Ser Leu Asn His Glu Tyr Leu Pro Ile Leu
                  65                  70                  75

 Gly Leu Ala Glu Phe Arg Ser Cys Ala Ser Arg Leu Ala Leu Gly
                  80                  85                  90

 Asp Asp Ser Pro Ala Leu Lys Glu Lys Arg Val Gly Gly Val Gln
                  95                 100                 105

 Ser Leu Gly Gly Thr Gly Ala Leu Arg Ile Gly Ala Asp Phe Leu
                 110                 115                 120

 Ala Arg Trp Tyr Asn Gly Thr Asn Asn Lys Asn Thr Pro Val Tyr
                 125                 130                 135

 Val Ser Ser Pro Thr Trp Glu Asn His Asn Ala Val Phe Ser Ala
                 140                 145                 150

 Ala Gly Phe Lys Asp Ile Arg Ser Tyr Arg Tyr Trp Asp Ala Glu
                 155                 160                 165

 Lys Arg Gly Leu Asp Leu Gln Gly Phe Leu Asn Asp Leu Glu Asn
                 170                 175                 180

 Ala Pro Glu Phe Ser Ile Val Val Leu His Ala Cys Ala His Asn
                 185                 190                 195

 Pro Thr Gly Ile Asp Pro Thr Pro Glu Gln Trp Lys Gln Ile Ala
                 200                 205                 210

 Ser Val Met Lys His Arg Phe Leu Phe Pro Phe Phe Asp Ser Ala
                 215                 220                 225

 Tyr Gln Gly Phe Ala Ser Gly Asn Leu Glu Arg Asp Ala Trp Ala
                 230                 235                 240

 Ile Arg Tyr Phe Val Ser Glu Gly Phe Glu Phe Phe Cys Ala Gln
                 245                 250                 255

 Ser Phe Ser Lys Asn Phe Gly Leu Tyr Asn Glu Arg Val Gly Asn
                 260                 265                 270

 Leu Thr Val Val Gly Lys Glu Pro Glu Ser Ile Leu Gln Val Leu
                 275                 280                 285

 Ser Gln Met Glu Lys Ile Val Arg Ile Thr Trp Ser Asn Pro Pro
                 290                 295                 300

 Ala Gln Gly Ala Arg Ile Val Ala Ser Thr Leu Ser Asn Pro Glu
                 305                 310                 315

 Leu Phe Glu Glu Trp Thr Gly Asn Val Lys Thr Met Ala Asp Arg
                 320                 325                 330

 Ile Leu Thr Met Arg Ser Glu Leu Arg Ala Arg Leu Glu Ala Leu
                 335                 340                 345

 Lys Thr Pro Gly Thr Trp Asn His Ile Thr Asp Gln Ile Gly Met
                 350                 355                 360

 Phe Ser Phe Thr Gly Leu Asn Pro Lys Gln Val Glu Tyr Leu Val
                 365                 370                 375

 Asn Glu Lys His Ile Tyr Leu Leu Pro Ser Gly Arg Ile Asn Val
                 380                 385                 390

 Ser Gly Leu Thr Thr Lys Asn Leu Asp Tyr Val Ala Thr Ser Ile
                 395                 400                 405

 His Glu Ala Val Thr Lys Ile Gln
                 410

<210> 1837
<211> 2839
<212> DNA
<213> Homo sapien

<400> 1837
 gcacgagctg cggctccgct ctcgtcgcaa cgagatcttt cgagatcttc 50

 tccgcccccg ctaccggcgc ctcctctgcg gccactgagc cggagccggc 100

 ctgagcagcg ctctcggttg cagtacccac tggaaggact taggcgctcg 150

 cgtggacacc gcaagcccct cagtagcctc ggcccaagag gcctgctttc 200

 cactcgctag ccccgccggg gtccgtgtcc tgtctcggtg gccggacccg 250

 ggcccgagcc cgagcagtag ccggcgccat gtcggtggtg ggcatagacc 300

 tgggcttcca gagctgctac gtcgctgtgg cccgcgccgg cggcatcgag 350

 actatcgcta atgagtatag cgaccgctgc acgccggctt gcatttcttt 400

 tggtcctaag aatcgttcaa ttggagcagc agctaaaagc caggtaattt 450

 ctaatgcaaa gaacacagtc caaggattta aaagattcca tggccgagca 500

 ttctctgatc catttgtgga ggcagaaaaa tctaaccttg catatgatat 550

 tgtgcagttg cctacaggat taacaggtat aaaggtgaca tatatggagg 600

 aagagcgaaa ttttaccact gagcaagtga ctgccatgct tttgtccaaa 650

 ctgaaggaga cagccgaaag tgttcttaag aagcctgtag ttgactgtgt 700

 tgtttcggtt ccttgtttct atactgatgc agaaagacga tcagtgatgg 750

 atgcaacaca gattgctggt cttaattgct tgcgattaat gaatgaaacc 800

 actgcagttg ctcttgcata tggaatctat aagcaggatc ttcctgcctt 850

 agaagagaaa ccaagaaatg tagtttttgt agacatgggc cactctgctt 900

 atcaagtttc tgtatgtgca tttaatagag gaaaactgaa agttctggcc 950

 actgcatttg acacgacatt gggaggtaga aaatttgatg aagtgttagt 1000

 aaatcacttc tgtgaagaat ttgggaagaa atacaagcta gacattaagt 1050

 ccaaaatccg tgcattatta cgactctctc aggagtgtga gaaactcaag 1100

 aaattgatga gtgcaaatgc ttcagatctc cctttgagca ttgaatgttt 1150

 tatgaatgat gttgatgtat ctggaactat gaatagaggc aaatttctgg 1200

 agatgtgcaa tgatctctta gctagagtgg agccaccact tcgtagtgtt 1250

 ttggaacaaa ccaagttaaa gaaagaagat atttatgcag tggagatagt 1300

 tggtggtgct acacgaatcc ctgcggtaaa agagaagatc agcaaatttt 1350

 tcggtaaaga acttagtaca acattaaatg ctgatgaagc tgtcactcga 1400

 ggctgtgcat tgcagtgtgc catcttatcg cctgctttca aagtcagaga 1450

 attttctatc actgatgtag taccatatcc aatatctctg agatggaatt 1500

 ctccagctga agaagggtca agtgactgtg aagtcttttc caaaaatcat 1550

 gctgctcctt tctctaaagt tcttacattt tatagaaagg aacctttcac 1600

 tcttgaggcc tactacagct ctcctcagga tttgccctat ccagatcctg 1650

 ctatagctca gttttcagtt cagaaagtca ctcctcagtc tgatggctcc 1700

 agttcaaaag tgaaagtcaa agttcgagta aatgtccatg gcattttcag 1750

 tgtgtccagt gcatctttag tggaggttca caagtctgag gaaaatgagg 1800

 agccaatgga aacagatcag aatgcaaagg aggaagagaa gatgcaagtg 1850

 gaccaggagg aaccacatgt tgaagagcaa cagcagcaga caccagcaga 1900

 aaataaggca gagtctgaag aaatggagac ctctcaagct ggatccaagg 1950

 ataaaaagat ggaccaacca ccccaagcca agaaggcaaa agtgaagacc 2000

 agtactgtgg acctgccaat cgagaatcag ctattatggc agatagacag 2050

 agagatgctc aacttgtaca ttgaaaatga gggtaagatg atcatgcagg 2100

 ataaactgga gaaggagcgg aatgatgcta agaacgcagt gagggaatat 2150

 gtgtatgaaa tgagagacaa gcttagtggt gaatatgaga agtttgtgag 2200

 tgaagatggt cgtaacagtt ttactttgaa actggaagat actgaaaatt 2250

 ggttgtatga ggatggagaa gaccagccaa agcaagttta tgttgataag 2300

 ttggctgaat taaaaaatct aggtcaacct attaagatac gtttccagga 2350

 atctgaagaa cgaccaaaat tatttgaaga actagggaaa cagatccaac 2400

 agtatatgaa aataatcagc tctttcaaaa acaaggagga ccagtatgat 2450

 catttggatg ctgctgacat gacaaaggta gaaaaaagca caaatgaagc 2500

 aatggagtgg atgaataaca agctaaatct gcagaacaag cagagtttga 2550

 ccatggatcc agttgtcaag tcaaaagaga ttgaagctaa aattaaggag 2600

 ctgacaagta cttgtagccc tataatttca aagcccaaac ccaaagtgga 2650

 acctccaaaa gaggaacaaa aaaatgcaga gcagaatgga ccagtggatg 2700

 gacaaggaga caacccaggc ccccaggctg ctgagcaggg tacagacaca 2750

 gctgtgcctt cggattcaga caagaagctt cctgaaatgg acattgattg 2800

 attccaacac ttgtttctat taaaacagac tattataaa 2839

<210> 1838
<211> 840
<212> PRT
<213> Homo sapien

<400> 1838
 Met Ser Val Val Gly Ile Asp Leu Gly Phe Gln Ser Cys Tyr Val
   1               5                  10                  15

 Ala Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Tyr
                  20                  25                  30

 Ser Asp Arg Cys Thr Pro Ala Cys Ile Ser Phe Gly Pro Lys Asn
                  35                  40                  45

 Arg Ser Ile Gly Ala Ala Ala Lys Ser Gln Val Ile Ser Asn Ala
                  50                  55                  60

 Lys Asn Thr Val Gln Gly Phe Lys Arg Phe His Gly Arg Ala Phe
                  65                  70                  75

 Ser Asp Pro Phe Val Glu Ala Glu Lys Ser Asn Leu Ala Tyr Asp
                  80                  85                  90

 Ile Val Gln Leu Pro Thr Gly Leu Thr Gly Ile Lys Val Thr Tyr
                  95                 100                 105

 Met Glu Glu Glu Arg Asn Phe Thr Thr Glu Gln Val Thr Ala Met
                 110                 115                 120

 Leu Leu Ser Lys Leu Lys Glu Thr Ala Glu Ser Val Leu Lys Lys
                 125                 130                 135

 Pro Val Val Asp Cys Val Val Ser Val Pro Cys Phe Tyr Thr Asp
                 140                 145                 150

 Ala Glu Arg Arg Ser Val Met Asp Ala Thr Gln Ile Ala Gly Leu
                 155                 160                 165

 Asn Cys Leu Arg Leu Met Asn Glu Thr Thr Ala Val Ala Leu Ala
                 170                 175                 180

 Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Ala Leu Glu Glu Lys Pro
                 185                 190                 195

 Arg Asn Val Val Phe Val Asp Met Gly His Ser Ala Tyr Gln Val
                 200                 205                 210

 Ser Val Cys Ala Phe Asn Arg Gly Lys Leu Lys Val Leu Ala Thr
                 215                 220                 225

 Ala Phe Asp Thr Thr Leu Gly Gly Arg Lys Phe Asp Glu Val Leu
                 230                 235                 240

 Val Asn His Phe Cys Glu Glu Phe Gly Lys Lys Tyr Lys Leu Asp
                 245                 250                 255

 Ile Lys Ser Lys Ile Arg Ala Leu Leu Arg Leu Ser Gln Glu Cys
                 260                 265                 270

 Glu Lys Leu Lys Lys Leu Met Ser Ala Asn Ala Ser Asp Leu Pro
                 275                 280                 285

 Leu Ser Ile Glu Cys Phe Met Asn Asp Val Asp Val Ser Gly Thr
                 290                 295                 300

 Met Asn Arg Gly Lys Phe Leu Glu Met Cys Asn Asp Leu Leu Ala
                 305                 310                 315

 Arg Val Glu Pro Pro Leu Arg Ser Val Leu Glu Gln Thr Lys Leu
                 320                 325                 330

 Lys Lys Glu Asp Ile Tyr Ala Val Glu Ile Val Gly Gly Ala Thr
                 335                 340                 345

 Arg Ile Pro Ala Val Lys Glu Lys Ile Ser Lys Phe Phe Gly Lys
                 350                 355                 360

 Glu Leu Ser Thr Thr Leu Asn Ala Asp Glu Ala Val Thr Arg Gly
                 365                 370                 375

 Cys Ala Leu Gln Cys Ala Ile Leu Ser Pro Ala Phe Lys Val Arg
                 380                 385                 390

 Glu Phe Ser Ile Thr Asp Val Val Pro Tyr Pro Ile Ser Leu Arg
                 395                 400                 405

 Trp Asn Ser Pro Ala Glu Glu Gly Ser Ser Asp Cys Glu Val Phe
                 410                 415                 420

 Ser Lys Asn His Ala Ala Pro Phe Ser Lys Val Leu Thr Phe Tyr
                 425                 430                 435

 Arg Lys Glu Pro Phe Thr Leu Glu Ala Tyr Tyr Ser Ser Pro Gln
                 440                 445                 450

 Asp Leu Pro Tyr Pro Asp Pro Ala Ile Ala Gln Phe Ser Val Gln
                 455                 460                 465

 Lys Val Thr Pro Gln Ser Asp Gly Ser Ser Ser Lys Val Lys Val
                 470                 475                 480

 Lys Val Arg Val Asn Val His Gly Ile Phe Ser Val Ser Ser Ala
                 485                 490                 495

 Ser Leu Val Glu Val His Lys Ser Glu Glu Asn Glu Glu Pro Met
                 500                 505                 510

 Glu Thr Asp Gln Asn Ala Lys Glu Glu Glu Lys Met Gln Val Asp
                 515                 520                 525

 Gln Glu Glu Pro His Val Glu Glu Gln Gln Gln Gln Thr Pro Ala
                 530                 535                 540

 Glu Asn Lys Ala Glu Ser Glu Glu Met Glu Thr Ser Gln Ala Gly
                 545                 550                 555

 Ser Lys Asp Lys Lys Met Asp Gln Pro Pro Gln Ala Lys Lys Ala
                 560                 565                 570

 Lys Val Lys Thr Ser Thr Val Asp Leu Pro Ile Glu Asn Gln Leu
                 575                 580                 585

 Leu Trp Gln Ile Asp Arg Glu Met Leu Asn Leu Tyr Ile Glu Asn
                 590                 595                 600

 Glu Gly Lys Met Ile Met Gln Asp Lys Leu Glu Lys Glu Arg Asn
                 605                 610                 615

 Asp Ala Lys Asn Ala Val Arg Glu Tyr Val Tyr Glu Met Arg Asp
                 620                 625                 630

 Lys Leu Ser Gly Glu Tyr Glu Lys Phe Val Ser Glu Asp Gly Arg
                 635                 640                 645

 Asn Ser Phe Thr Leu Lys Leu Glu Asp Thr Glu Asn Trp Leu Tyr
                 650                 655                 660

 Glu Asp Gly Glu Asp Gln Pro Lys Gln Val Tyr Val Asp Lys Leu
                 665                 670                 675

 Ala Glu Leu Lys Asn Leu Gly Gln Pro Ile Lys Ile Arg Phe Gln
                 680                 685                 690

 Glu Ser Glu Glu Arg Pro Lys Leu Phe Glu Glu Leu Gly Lys Gln
                 695                 700                 705

 Ile Gln Gln Tyr Met Lys Ile Ile Ser Ser Phe Lys Asn Lys Glu
                 710                 715                 720

 Asp Gln Tyr Asp His Leu Asp Ala Ala Asp Met Thr Lys Val Glu
                 725                 730                 735

 Lys Ser Thr Asn Glu Ala Met Glu Trp Met Asn Asn Lys Leu Asn
                 740                 745                 750

 Leu Gln Asn Lys Gln Ser Leu Thr Met Asp Pro Val Val Lys Ser
                 755                 760                 765

 Lys Glu Ile Glu Ala Lys Ile Lys Glu Leu Thr Ser Thr Cys Ser
                 770                 775                 780

 Pro Ile Ile Ser Lys Pro Lys Pro Lys Val Glu Pro Pro Lys Glu
                 785                 790                 795

 Glu Gln Lys Asn Ala Glu Gln Asn Gly Pro Val Asp Gly Gln Gly
                 800                 805                 810

 Asp Asn Pro Gly Pro Gln Ala Ala Glu Gln Gly Thr Asp Thr Ala
                 815                 820                 825

 Val Pro Ser Asp Ser Asp Lys Lys Leu Pro Glu Met Asp Ile Asp
                 830                 835                 840

<210> 1839
<211> 849
<212> DNA
<213> Homo sapien

<400> 1839
 acagttgctt tgaggcagta ccggaggaga aagatggcgg ctaccttact 50

 agctgctcgg ggagccgggc cagcaccggc ttgggggccg gaggcgttca 100

 ctccagactg ggaaagccga gaagtttcca ctgggaccac tatcatggcc 150

 gtgcagtttg acgggggcgt ggttctgggg gcggactcca gaacaaccac 200

 tgggtcctac atcgccaatc gagtgactga caagctgaca cctattcacg 250

 accgcatttt ctgctgtcgc tcaggctcag ctgctgatac ccaggcagta 300

 gctgatgctg tcacctacca gctcggtttc cacagcattg aactgaatga 350

 gcctccactg gtccacacag cagccagcct ctttaaggag atgtgttacc 400

 gataccggga agacctgatg gcgggaatca tcatcgcagg ctgggaccct 450

 caagaaggag ggcaggtgta ctcagtgcct atggggggta tgatggtaag 500

 gcagtccttt gccattggag gctccgggag ctcctacatc tatggctatg 550

 ttgatgctac ctaccgggaa ggcatgacca aggaagagtg tctgcaattc 600

 actgccaatg ctctcgcttt ggccatggag cgggatggct ccagtggagg 650

 agtgatccgc ctggcagcca ttgcagagtc aggggtagag cggcaagtac 700

 ttttgggaga ccagataccc aaattcgccg ttgccacttt accacccgcc 750

 tgaatcctgg gattctagta tgcaataaga gatgccctgt actgatgcaa 800

 aatttaataa agtttgtcac agagaaaaaa aaaaaaaaaa aaaaaaaaa 849

<210> 1840
<211> 239
<212> PRT
<213> Homo sapien

<400> 1840
 Met Ala Ala Thr Leu Leu Ala Ala Arg Gly Ala Gly Pro Ala Pro
   1               5                  10                  15

 Ala Trp Gly Pro Glu Ala Phe Thr Pro Asp Trp Glu Ser Arg Glu
                  20                  25                  30

 Val Ser Thr Gly Thr Thr Ile Met Ala Val Gln Phe Asp Gly Gly
                  35                  40                  45

 Val Val Leu Gly Ala Asp Ser Arg Thr Thr Thr Gly Ser Tyr Ile
                  50                  55                  60

 Ala Asn Arg Val Thr Asp Lys Leu Thr Pro Ile His Asp Arg Ile
                  65                  70                  75

 Phe Cys Cys Arg Ser Gly Ser Ala Ala Asp Thr Gln Ala Val Ala
                  80                  85                  90

 Asp Ala Val Thr Tyr Gln Leu Gly Phe His Ser Ile Glu Leu Asn
                  95                 100                 105

 Glu Pro Pro Leu Val His Thr Ala Ala Ser Leu Phe Lys Glu Met
                 110                 115                 120

 Cys Tyr Arg Tyr Arg Glu Asp Leu Met Ala Gly Ile Ile Ile Ala
                 125                 130                 135

 Gly Trp Asp Pro Gln Glu Gly Gly Gln Val Tyr Ser Val Pro Met
                 140                 145                 150

 Gly Gly Met Met Val Arg Gln Ser Phe Ala Ile Gly Gly Ser Gly
                 155                 160                 165

 Ser Ser Tyr Ile Tyr Gly Tyr Val Asp Ala Thr Tyr Arg Glu Gly
                 170                 175                 180

 Met Thr Lys Glu Glu Cys Leu Gln Phe Thr Ala Asn Ala Leu Ala
                 185                 190                 195

 Leu Ala Met Glu Arg Asp Gly Ser Ser Gly Gly Val Ile Arg Leu
                 200                 205                 210

 Ala Ala Ile Ala Glu Ser Gly Val Glu Arg Gln Val Leu Leu Gly
                 215                 220                 225

 Asp Gln Ile Pro Lys Phe Ala Val Ala Thr Leu Pro Pro Ala
                 230                 235

<210> 1841
<211> 4117
<212> DNA
<213> Homo sapien

<400> 1841
 tccgcctctc tctttactgc ggcgcggggc aaggtgtgcg ggcgggaagg 50

 ggcacgggca cccccgcggt ccccgggagg ctagagatca tggaagggaa 100

 gtggttgctg tgtatgttac tggtgcttgg aactgctatt gttgaggctc 150

 atgatggaca tgatgatgat gtgattgata ttgaggatga ccttgacgat 200

 gtcattgaag aggtagaaga ctcaaaacca gataccactg ctcctccttc 250

 atctcccaag gttacttaca aagctccagt tccaacaggg gaagtatatt 300

 ttgctgattc ttttgacaga ggaactctgt cagggtggat tttatccaaa 350

 gccaagaaag acgataccga tgatgaaatt gccaaatatg atggaaagtg 400

 ggaggtagag gaaatgaagg agtcaaagct tccaggtgat aaaggacttg 450

 tgttgatgtc tcgggccaag catcatgcga tctctgctaa actgaacaag 500

 cccttcctgt ttgacaccaa gcctctcatt gttcagtatg aggttaattt 550

 ccaaaatgga atagaatgtg gtggtgccta tgtgaaactg ctttctaaaa 600

 caccagaact caacctggat cagttccatg acaagacccc ttatacgatt 650

 atgtttggtc cagataaatg tggagaggac tataaactgc acttcatctt 700

 ccgacacaaa aaccccaaaa cgggtatcta tgaagaaaaa catgctaaga 750

 ggccagatgc agatctgaag acctatttta ctgataagaa aacacatctt 800

 tacacactaa tcttgaatcc agataatagt tttgaaatac tggttgacca 850

 atctgtggtg aatagtggaa atctgctcaa tgacatgact cctcctgtaa 900

 atccttcacg tgaaattgag gacccagaag accggaagcc cgaggattgg 950

 gatgaaagac caaaaatccc agatccagaa gctgtcaagc cagatgactg 1000

 ggatgaagat gcccctgcta agattccaga tgaagaggcc acaaaacccg 1050

 aaggctggtt agatgatgag cctgagtacg tacctgatcc agacgcagag 1100

 aaacctgagg attgggatga agacatggat ggagaatggg aggctcctca 1150

 gattgccaac cctagatgtg agtcagctcc tggatgtggt gtctggcagc 1200

 gacctgtgat tgacaacccc aattataaag gcaaatggaa gcctcctatg 1250

 attgacaatc ccagttacca gggaatctgg aaacccagga aaataccaaa 1300

 tccagatttc tttgaagatc tggaaccttt cagaatgact ccttttagtg 1350

 ctattggttt ggagctgtgg tccatgacct ctgacatttt ttttgacaac 1400

 tttatcattt gtgctgatcg aagaatagtt gatgattggg ccaatgatgg 1450

 atggggcctg aagaaagctg ctgatggggc tgctgagcca ggcgttgtgg 1500

 ggcagatgat cgaggcagct gaagagcgcc cgtggctgtg ggtagtctat 1550

 attctaactg tagcccttcc tgtgttcctg gttatcctct tctgctgttc 1600

 tggaaagaaa cagaccagtg gtatggagta taagaaaact gatgcacctc 1650

 aaccggatgt gaaggaagag gaagaagaga aggaagagga aaaggacaag 1700

 ggagatgagg aggaggaagg agaagagaaa cttgaagaga aacagaaaag 1750

 tgatgctgaa gaagatggtg gcactgtcag tcaagaggag gaagacagaa 1800

 aacctaaagc agaggaggat gaaattttga acagatcacc aagaaacaga 1850

 aagccacgaa gagagtgaaa caatcttaag agcttgatct gtgatttctt 1900

 ctccctcctc ccctgcaaga gtggtcctag gagaggacct ggcacacctt 1950

 aggttgacat tcagaaaact tcaagacatc accatcagca ggctccagtt 2000

 gaacactagt ctgtgtaact ttaaacatct agcagtaaat acttgcagtt 2050

 gtgatataaa ggaccctgtt tctgtagaaa agaaaacatt taacataatg 2100

 gttgtgaaat gtaacatgaa gcaaactaac tttttttttt ttaacatctt 2150

 tgtttttaaa atagaatgat agaactttgc cagtctttaa gatcttggct 2200

 taatttaatg tattaatctg tttgtgcaaa cataatacca ccatttaaaa 2250

 atgttaggga gatgagttgc agtttttata atagattttt tttaaagttt 2300

 ggtattgtaa aacattcaca cctctgtccc tcaaaattga taattacgtt 2350

 taaagtgcag tcatttgtgg ttagaatctt gttttgtttg cttccattat 2400

 tgagttcctc ctaaggaaat tgaggagagg gactgaatag aagcccaaat 2450

 tcatataaaa gttgcgttta agttgtatta aaaatagata tataagaaaa 2500

 aattctttca cttgatgttt gttagaccag aaagtgtgtg tgttctgtag 2550

 ctcagttccc agacagcttt ttaggtagtg gaggaggtgg cttcatgtgg 2600

 cacttgggca tttatattcc acttgggagg gtcaggcctg tggcttctgg 2650

 agcaggtggc ttgttaagga acgctagcag ggcatggcac gtgagctccg 2700

 gaatagatgt cttcatcact tcttccactg tgtgttgaca ctgttttcct 2750

 tacctatttc ctcagatccc cagctttctc ctcgctatgc attttcttca 2800

 cagtgcagct tgcagtccgt tgctgaaaat gattataagc cctgcataat 2850

 gttaagcttt attgtgatta cgtgtatgtt tcttctttct tttaagcaga 2900

 cccatacctt tccagggtca aagtacagaa tagaatacat tgatacaaag 2950

 tacagaaaaa tactttgatt tttatccatt tcttttactc tgtgtaaaga 3000

 ctttagaagt ctaattcaca ggcaaaccaa tacagaattg actgcagttg 3050

 aacagactag aagtatttgt gggaggagtg acatgaagca tgagttatct 3100

 gatttttttt gtagctgcta tatattttaa gccttcattt gcaattcatg 3150

 taacagttgt gtcataaatt acacaataaa gcagtcctgt tcaaattttt 3200

 ttttaacgtg gcttgtagaa tttttaaaaa agtgatctta ggtttgtttt 3250

 ttcatgcggg atgcagatgg gtgctatcag agcctctccc acaccactat 3300

 agtgtaataa tgttattatt actctacact gaaacgtatt cagagttaga 3350

 tattatttta gcttcagttg ttctttagag gctttcaaat gtaccgatga 3400

 tactgtttct tgcactgaat atataaacac tccacagtgt ttatattggg 3450

 aagatattgg gaaggaaata tatttgtaaa agatgaaggc tgtatctatt 3500

 tttttttctt tttaaactgg ttcacttaaa ttcttttgag gatgggatgt 3550

 atttttcttg ctgttcagtg ctttttcctt ttcatctgtt gttctgtggt 3600

 cacagtgacc ttagctacat agcagacttt cccaaatgta ttgattacaa 3650

 ataaacagtt gttacttagc aagacctgaa aatatgtctg caggtttctc 3700

 cttgaagcaa atgtgtggga tcattgcatt tccagaaatc tgcctccttc 3750

 acccaccgtt gacagtatat gtcatgcctc actttcttgt agctgagctt 3800

 taaatcatta gagcttaaat tgtcagatcg ttcattgcct ttccagggtt 3850

 atttagtaaa gtttgttgaa aacaaaaacg ccttttcttg gttctttttt 3900

 cagttatttt gaaggtccag catcctgatt aaatgtctga cacttaatga 3950

 atgaccagca gcagctttca gctcttaaaa agacacttat attttgattt 4000

 tacatgctgg ttacctgttc cattgttgtc aaatgcccag tgtccatcag 4050

 atgtgttcct ccattttctt atccacaaag tactcctcac ttttcaattt 4100

 gtcatgttac taaaccc 4117

<210> 1842
<211> 592
<212> PRT
<213> Homo sapien

<400> 1842
 Met Glu Gly Lys Trp Leu Leu Cys Met Leu Leu Val Leu Gly Thr
   1               5                  10                  15

 Ala Ile Val Glu Ala His Asp Gly His Asp Asp Asp Val Ile Asp
                  20                  25                  30

 Ile Glu Asp Asp Leu Asp Asp Val Ile Glu Glu Val Glu Asp Ser
                  35                  40                  45

 Lys Pro Asp Thr Thr Ala Pro Pro Ser Ser Pro Lys Val Thr Tyr
                  50                  55                  60

 Lys Ala Pro Val Pro Thr Gly Glu Val Tyr Phe Ala Asp Ser Phe
                  65                  70                  75

 Asp Arg Gly Thr Leu Ser Gly Trp Ile Leu Ser Lys Ala Lys Lys
                  80                  85                  90

 Asp Asp Thr Asp Asp Glu Ile Ala Lys Tyr Asp Gly Lys Trp Glu
                  95                 100                 105

 Val Glu Glu Met Lys Glu Ser Lys Leu Pro Gly Asp Lys Gly Leu
                 110                 115                 120

 Val Leu Met Ser Arg Ala Lys His His Ala Ile Ser Ala Lys Leu
                 125                 130                 135

 Asn Lys Pro Phe Leu Phe Asp Thr Lys Pro Leu Ile Val Gln Tyr
                 140                 145                 150

 Glu Val Asn Phe Gln Asn Gly Ile Glu Cys Gly Gly Ala Tyr Val
                 155                 160                 165

 Lys Leu Leu Ser Lys Thr Pro Glu Leu Asn Leu Asp Gln Phe His
                 170                 175                 180

 Asp Lys Thr Pro Tyr Thr Ile Met Phe Gly Pro Asp Lys Cys Gly
                 185                 190                 195

 Glu Asp Tyr Lys Leu His Phe Ile Phe Arg His Lys Asn Pro Lys
                 200                 205                 210

 Thr Gly Ile Tyr Glu Glu Lys His Ala Lys Arg Pro Asp Ala Asp
                 215                 220                 225

 Leu Lys Thr Tyr Phe Thr Asp Lys Lys Thr His Leu Tyr Thr Leu
                 230                 235                 240

 Ile Leu Asn Pro Asp Asn Ser Phe Glu Ile Leu Val Asp Gln Ser
                 245                 250                 255

 Val Val Asn Ser Gly Asn Leu Leu Asn Asp Met Thr Pro Pro Val
                 260                 265                 270

 Asn Pro Ser Arg Glu Ile Glu Asp Pro Glu Asp Arg Lys Pro Glu
                 275                 280                 285

 Asp Trp Asp Glu Arg Pro Lys Ile Pro Asp Pro Glu Ala Val Lys
                 290                 295                 300

 Pro Asp Asp Trp Asp Glu Asp Ala Pro Ala Lys Ile Pro Asp Glu
                 305                 310                 315

 Glu Ala Thr Lys Pro Glu Gly Trp Leu Asp Asp Glu Pro Glu Tyr
                 320                 325                 330

 Val Pro Asp Pro Asp Ala Glu Lys Pro Glu Asp Trp Asp Glu Asp
                 335                 340                 345

 Met Asp Gly Glu Trp Glu Ala Pro Gln Ile Ala Asn Pro Arg Cys
                 350                 355                 360

 Glu Ser Ala Pro Gly Cys Gly Val Trp Gln Arg Pro Val Ile Asp
                 365                 370                 375

 Asn Pro Asn Tyr Lys Gly Lys Trp Lys Pro Pro Met Ile Asp Asn
                 380                 385                 390

 Pro Ser Tyr Gln Gly Ile Trp Lys Pro Arg Lys Ile Pro Asn Pro
                 395                 400                 405

 Asp Phe Phe Glu Asp Leu Glu Pro Phe Arg Met Thr Pro Phe Ser
                 410                 415                 420

 Ala Ile Gly Leu Glu Leu Trp Ser Met Thr Ser Asp Ile Phe Phe
                 425                 430                 435

 Asp Asn Phe Ile Ile Cys Ala Asp Arg Arg Ile Val Asp Asp Trp
                 440                 445                 450

 Ala Asn Asp Gly Trp Gly Leu Lys Lys Ala Ala Asp Gly Ala Ala
                 455                 460                 465

 Glu Pro Gly Val Val Gly Gln Met Ile Glu Ala Ala Glu Glu Arg
                 470                 475                 480

 Pro Trp Leu Trp Val Val Tyr Ile Leu Thr Val Ala Leu Pro Val
                 485                 490                 495

 Phe Leu Val Ile Leu Phe Cys Cys Ser Gly Lys Lys Gln Thr Ser
                 500                 505                 510

 Gly Met Glu Tyr Lys Lys Thr Asp Ala Pro Gln Pro Asp Val Lys
                 515                 520                 525

 Glu Glu Glu Glu Glu Lys Glu Glu Glu Lys Asp Lys Gly Asp Glu
                 530                 535                 540

 Glu Glu Glu Gly Glu Glu Lys Leu Glu Glu Lys Gln Lys Ser Asp
                 545                 550                 555

 Ala Glu Glu Asp Gly Gly Thr Val Ser Gln Glu Glu Glu Asp Arg
                 560                 565                 570

 Lys Pro Lys Ala Glu Glu Asp Glu Ile Leu Asn Arg Ser Pro Arg
                 575                 580                 585

 Asn Arg Lys Pro Arg Arg Glu
                 590

<210> 1843
<211> 501
<212> DNA
<213> Homo sapien

<400> 1843
 gaattcgctt tggatccatt tccatcggtc cttacagccg ctcgtcagac 50

 tccagcagcc aagatggtga agcagatcga gagcaagact gcttttcagg 100

 aagccttgga cgctgcaggt gataaacttg tagtagttga cttctcagcc 150

 acgtggtgtg ggccttgcaa aatgatcaac cctttctttc attccctctc 200

 tgaaaagtat tccaacgtga tattccttga agtagatgtg gatgactgtc 250

 aggatgttgc ttcagagtgt gaagtcaaat gcacgccaac attccagttt 300

 tttaagaagg gacaaaaggt gggtgaattt tctggagcca ataaggaaaa 350

 gcttgaagcc accattaatg aattagtcta atcatgtttt ctgaaaacat 400

 aaccagccat tggctattta aacttgtatt tttttattta caaaatataa 450

 atatgaagac ataaccagtt gccatctgcg tgacaataaa cattatgcta 500

 a 501

<210> 1844
<211> 105
<212> PRT
<213> Homo sapien

<400> 1844
 Met Val Lys Gln Ile Glu Ser Lys Thr Ala Phe Gln Glu Ala Leu
   1               5                  10                  15

 Asp Ala Ala Gly Asp Lys Leu Val Val Val Asp Phe Ser Ala Thr
                  20                  25                  30

 Trp Cys Gly Pro Cys Lys Met Ile Asn Pro Phe Phe His Ser Leu
                  35                  40                  45

 Ser Glu Lys Tyr Ser Asn Val Ile Phe Leu Glu Val Asp Val Asp
                  50                  55                  60

 Asp Cys Gln Asp Val Ala Ser Glu Cys Glu Val Lys Cys Thr Pro
                  65                  70                  75

 Thr Phe Gln Phe Phe Lys Lys Gly Gln Lys Val Gly Glu Phe Ser
                  80                  85                  90

 Gly Ala Asn Lys Glu Lys Leu Glu Ala Thr Ile Asn Glu Leu Val
                  95                 100                 105

<210> 1845
<211> 1933
<212> DNA
<213> Homo sapien

<400> 1845
 cgtcacagcc cgacgcgcca cccagctgtt tttgtgctca caagctctag 50

 cgaaaagccg ccggtatttc tccatctggc tctcctctac ctccaggcag 100

 gctcacccga gatccccgcc ccgaaccccc cctgcacact cggcccagcg 150

 ctgttgcccc cggagcggac gtttctgcag ctattctgag cacaccttga 200

 cgtcggctga gggagcggga cagggtcagc ggcgaaggag gcaggccccg 250

 cgcggggatc tcggaagccc tgcggtgcat catgaagttc cagtacaagg 300

 aggaccatcc ctttgagtat cggaaaaagg aaggagaaaa gatccggaag 350

 aaatatccgg acagggtccc cgtgattgta gagaaggctc caaaagccag 400

 ggtgcctgat ctggacaaga ggaagtacct agtgccctct gaccttactg 450

 ttggccagtt ctacttctta atccggaaga gaatccacct gagacctgag 500

 gacgccttat tcttctttgt caacaacacc atccctccca ccagtgctac 550

 catgggccaa ctgtatgagg acaatcatga ggaagactat tttctgtatg 600

 tggcctacag tgatgagagt gtctatggga aatgagtggt tggaagccca 650

 gcagatggga gcacctggac ttgggggtag gggaggggtg tgtgtgcgcg 700

 acatggggaa agagggtggc tcccaccgca aggagacaga aggtgaagac 750

 atctagaaac attacaccac acacaccgtc atcacatttt cacatgctca 800

 attgatattt tttgctgctt cctcggccca gggagaaagc atgtcaggac 850

 agagctgttg gattggcttt gatagaggaa tggggatgat gtaagtttac 900

 agtattcctg gggtttaatt gttgtgcagt ttcatagatg ggtcaggagg 950

 tggacaagtt ggggccagag atgatggcag tccagcagca actccctgtg 1000

 ctcccttctc tttgggcaga gattctattt ttgacatttg cacaagacag 1050

 gtagggaaag gggacttgtg gtagtggacc atacctgggg accaaaagag 1100

 acccactgta attgatgcat tgtggcccct gatcttccct gtctcacact 1150

 tcttttctcc catcccggtt gcaatctcac tcagacatca cagtaccacc 1200

 ccaggggtgg cagtagacaa caacccagaa atttagacag ggatctctta 1250

 cctttggaaa ataggggtta ggcatgaagg tggttgtgat taagaagatg 1300

 gttttgttat taaatagcat taaactggaa ttgacaagag tgttgagcat 1350

 ccctgtctaa cctgctcttt ctctttggtg ccccttatct caccccttcc 1400

 ttggaattta ataagtctca ggcatttcca attgtagact aaaaccactc 1450

 ttagcatctc ctctagtatt ttccatgtat caggacagag gtgtcttatg 1500

 tagggagggg gcaagtatga agtaaggtaa ttatatacta ctctcattca 1550

 ggattcttgc tcccatgctg ctgtcccttc aggctcacat gcacaggaat 1600

 gctacatgat ggccagctgc ttccctcctt ggttatcatc cactgcagct 1650

 gctagttaga aaggtttgga gggatgactt ttagtaaatc atggggattt 1700

 tattgattta ttttcacttt tgggattttg tggggtggga gtggggagca 1750

 ggaattgcac tcagacatga catttcaatt catctctgct aatgaaaagg 1800

 gttctttctc ttgggggaaa tgtgtgtgtc agttctgtca gctgcaagtt 1850

 cttgtataat gaagtcaatg ccatcaggcc aaggaaataa aataattgct 1900

 taccttaaaa aaaaaaaaaa aaaaaaaaaa aaa 1933

<210> 1846
<211> 117
<212> PRT
<213> Homo sapien

<400> 1846
 Met Lys Phe Gln Tyr Lys Glu Asp His Pro Phe Glu Tyr Arg Lys
   1               5                  10                  15

 Lys Glu Gly Glu Lys Ile Arg Lys Lys Tyr Pro Asp Arg Val Pro
                  20                  25                  30

 Val Ile Val Glu Lys Ala Pro Lys Ala Arg Val Pro Asp Leu Asp
                  35                  40                  45

 Lys Arg Lys Tyr Leu Val Pro Ser Asp Leu Thr Val Gly Gln Phe
                  50                  55                  60

 Tyr Phe Leu Ile Arg Lys Arg Ile His Leu Arg Pro Glu Asp Ala
                  65                  70                  75

 Leu Phe Phe Phe Val Asn Asn Thr Ile Pro Pro Thr Ser Ala Thr
                  80                  85                  90

 Met Gly Gln Leu Tyr Glu Asp Asn His Glu Glu Asp Tyr Phe Leu
                  95                 100                 105

 Tyr Val Ala Tyr Ser Asp Glu Ser Val Tyr Gly Lys
                 110                 115

<210> 1847
<211> 2709
<212> DNA
<213> Homo sapien

<400> 1847
 cttggaggga gggattagaa gccgctagac tttttttcct cccctctcag 50

 tagcacggag tccgaattaa ttggatttca ttcactgggg aggaacaaaa 100

 actatctggg cagcttcatt gagagagatt cattgacact aagagccagc 150

 ggctgcagct gggtgcagag agaacctccg gctttacttc tgtctcgtct 200

 gccccaaccg ctagcctcgg cttgggtaag gcgaggcgga attaaacccc 250

 gctccgagag cggcagcttc gcgcgcggtg cgctcggcct atgcctgccc 300

 cgaggggcgt ctggtaggca ccccgccctc tcccgcagct cgacccccat 350

 gatagatacg ctcagacccg tgcccttcgc gtcggaaatg gcgatcagca 400

 agacggtggc gtggctcaac gagcagctgg agctgggcaa cgagcggctg 450

 ctgctgatgg actgccggcc gcaggagcta tacgagtcgt cgcacatcga 500

 gtcggccatc aacgtggcca tcccgggcat catgctgcgg cgcctgcaga 550

 agggtaacct gccggtgcgc gcgctcttca cgcgcggcga ggaccgggac 600

 cgcttcaccc ggcgctgtgg caccgacaca gtggtgctct acgacgagag 650

 cagcagcgac tggaacgaga atacgggcgg cgagtcgttg ctcgggctgc 700

 tgctcaagaa gctcaaggac gagggctgcc gggcgttcta cctggaaggt 750

 ggcttcagta agttccaagc cgagttctcc ctgcattgcg agaccaatct 800

 agacggctcg tgtagcagca gctcgccgcc gttgccagtg ctggggctcg 850

 ggggcctgcg gatcagctct gactcttcct cggacatcga gtctgacctt 900

 gaccgagacc ccaatagtgc aacagactcg gatggtagtc cgctgtccaa 950

 cagccagcct tccttcccag tggagatctt gcccttcctc tacttgggct 1000

 gtgccaaaga ctccaccaac ttggacgtgt tggaggaatt cggcatcaag 1050

 tacatcttga acgtcacccc caatttgccg aatctctttg agaacgcagg 1100

 agagtttaaa tacaagcaaa tccccatctc ggatcactgg agccaaaacc 1150

 tgtcccagtt tttccctgag gccatttctt tcatagatga agcccggggc 1200

 aagaactgtg gtgtcttggt acattgcttg gctggcatta gccgctcagt 1250

 cactgtgact gtggcttacc ttatgcagaa gctcaatctg tcgatgaacg 1300

 atgcctatga cattgtcaaa atgaaaaaat ccaacatatc ccctaacttc 1350

 aacttcatgg gtcagctgct ggacttcgag aggacgctgg gactcagcag 1400

 cccatgtgac aacagggttc cagcacagca gctgtatttt accacccctt 1450

 ccaaccagaa tgtataccag gtggactctc tgcaatctac gtgaaagacc 1500

 ccacatccct ccttgctgga atgtgtctgg cccttcagca gtttctcttg 1550

 gcagcatcag ctgggctgct ttctttgtgt gtggccccag gtgtcaaaat 1600

 gacaccagct gtctgtacta gacaaggtta ccaagtgcgg aattggttaa 1650

 tactaacaga gagatttgct ccattctctt tggaataaca ggacatgctg 1700

 tatagataca ggcagtaggt ttgctctgta cccatgtgta cagcctaccc 1750

 atgcagggac tgggattcga ggacttccag gcgcataggg tagaaccaaa 1800

 tgatagggta ggagcatgtg ttctttaggg ccttgtaagg ctgtttcctt 1850

 ttgcatctgg aactgactat ataattgtct tcaatgaaga ctaattcaat 1900

 tttgcatata gaggagccaa agagagattt cagctctgta tttgtggtat 1950

 cagtttggaa aaaaaaatct gatactccat ttgattattg taaatatttg 2000

 atcttgaatc acttgacagt gtttgtttga attgtgtttg ttttttcctt 2050

 tgatgggctt aaaagaaatt atccaaaggg agaaagagca gtatgccact 2100

 tcttaaaaca gaacaaaaca aaaaaagaaa attgtgctct tttctaatcc 2150

 aaagggtata tttgcagcat gcttgacttt accaattctg atgacatctt 2200

 tacggacact attatcacta agaccttgtt atggcgaagt ctttagtctt 2250

 tttcatgtat tttcctcatg attttttctc tttatgtagt ttgactatgc 2300

 cttacctttg taaatatttt tgcttgtgtt gtcgcaaagg ggataatctg 2350

 ggaaagacac caaatcatgg gctcacttta aaaaaagaaa gaataaaaaa 2400

 accttcagct gtgctaaaca gtatattacc tctgtataaa attcttcagg 2450

 gagtgtcacc tcaaatgcaa tactttgggt tggtttcttt cctttaaaaa 2500

 aatttgtata aaactggaag tgtgtgtgtg tgagcatggg tacccatttg 2550

 ataagagaaa tgcatttgat tgtgaagaag ggagagttaa attctccatt 2600

 atgttcgtgg tgtaaagttt agagctggaa tttattataa gaatgtaaaa 2650

 ccttaaatta ttaataaata actattttgg ctattgaaaa aaaaaaaaaa 2700

 aaaaaaaaa 2709

<210> 1848
<211> 381
<212> PRT
<213> Homo sapien

<400> 1848
 Met Ile Asp Thr Leu Arg Pro Val Pro Phe Ala Ser Glu Met Ala
   1               5                  10                  15

 Ile Ser Lys Thr Val Ala Trp Leu Asn Glu Gln Leu Glu Leu Gly
                  20                  25                  30

 Asn Glu Arg Leu Leu Leu Met Asp Cys Arg Pro Gln Glu Leu Tyr
                  35                  40                  45

 Glu Ser Ser His Ile Glu Ser Ala Ile Asn Val Ala Ile Pro Gly
                  50                  55                  60

 Ile Met Leu Arg Arg Leu Gln Lys Gly Asn Leu Pro Val Arg Ala
                  65                  70                  75

 Leu Phe Thr Arg Gly Glu Asp Arg Asp Arg Phe Thr Arg Arg Cys
                  80                  85                  90

 Gly Thr Asp Thr Val Val Leu Tyr Asp Glu Ser Ser Ser Asp Trp
                  95                 100                 105

 Asn Glu Asn Thr Gly Gly Glu Ser Leu Leu Gly Leu Leu Leu Lys
                 110                 115                 120

 Lys Leu Lys Asp Glu Gly Cys Arg Ala Phe Tyr Leu Glu Gly Gly
                 125                 130                 135

 Phe Ser Lys Phe Gln Ala Glu Phe Ser Leu His Cys Glu Thr Asn
                 140                 145                 150

 Leu Asp Gly Ser Cys Ser Ser Ser Ser Pro Pro Leu Pro Val Leu
                 155                 160                 165

 Gly Leu Gly Gly Leu Arg Ile Ser Ser Asp Ser Ser Ser Asp Ile
                 170                 175                 180

 Glu Ser Asp Leu Asp Arg Asp Pro Asn Ser Ala Thr Asp Ser Asp
                 185                 190                 195

 Gly Ser Pro Leu Ser Asn Ser Gln Pro Ser Phe Pro Val Glu Ile
                 200                 205                 210

 Leu Pro Phe Leu Tyr Leu Gly Cys Ala Lys Asp Ser Thr Asn Leu
                 215                 220                 225

 Asp Val Leu Glu Glu Phe Gly Ile Lys Tyr Ile Leu Asn Val Thr
                 230                 235                 240

 Pro Asn Leu Pro Asn Leu Phe Glu Asn Ala Gly Glu Phe Lys Tyr
                 245                 250                 255

 Lys Gln Ile Pro Ile Ser Asp His Trp Ser Gln Asn Leu Ser Gln
                 260                 265                 270

 Phe Phe Pro Glu Ala Ile Ser Phe Ile Asp Glu Ala Arg Gly Lys
                 275                 280                 285

 Asn Cys Gly Val Leu Val His Cys Leu Ala Gly Ile Ser Arg Ser
                 290                 295                 300

 Val Thr Val Thr Val Ala Tyr Leu Met Gln Lys Leu Asn Leu Ser
                 305                 310                 315

 Met Asn Asp Ala Tyr Asp Ile Val Lys Met Lys Lys Ser Asn Ile
                 320                 325                 330

 Ser Pro Asn Phe Asn Phe Met Gly Gln Leu Leu Asp Phe Glu Arg
                 335                 340                 345

 Thr Leu Gly Leu Ser Ser Pro Cys Asp Asn Arg Val Pro Ala Gln
                 350                 355                 360

 Gln Leu Tyr Phe Thr Thr Pro Ser Asn Gln Asn Val Tyr Gln Val
                 365                 370                 375

 Asp Ser Leu Gln Ser Thr
                 380

<210> 1849
<211> 2390
<212> DNA
<213> Homo sapien

<400> 1849
 ccagcctcgg agggagggat tagaagccgc tagacttttt ttcctcccct 50

 ctcagtagca cggagtccga attaattgga tttcattcac tggggaggaa 100

 caaaaactat ctgggcagct tcattgagag agattcattg acactaagag 150

 ccagcgctgc agctggtgca gagagaacct ccggctttga cttctgtctc 200

 gtctgcccca aggccgctag cctcggcttg ggaaggcgag gcggaattaa 250

 accccgctcc gagagcgcac gttcgcgcgc ggtgcgtcgg ccattgcctg 300

 ccccgagggg cgtctggtag gcaccccgcc ctctcccgca gctcgacccc 350

 catgatagat acgctcagac ccgtgccctt cgcgtcggaa atggcgatca 400

 gcaagacggt ggcgtggctc aacgagcagc tggagctggg caacgagcgg 450

 ctgctgctga tggactgccg gccgcaggag ctatacgagt cgtcgcacat 500

 cgagtcggcc atcaacgtgg ccatcccggg catcatgctg cggcgcctgc 550

 agaagggtaa cctgccggtg cgcgcgctct tcacgcgcgg cgaggaccgg 600

 gaccgcttca cccggcgctg tggcaccgac acagtggtgc tctacgacga 650

 gagcagcagc gactggaacg agaatacggg cggcgagtcg ttgctcgggc 700

 tgctgctcaa gaagctcaag gacgagggct gccgggcgtt ctacctggaa 750

 ggtggcttca gtaagttcca agccgagttc tccctgcatt gcgagaccaa 800

 tctagacggc tcgtgtagca gcagctcgcc gccgttgcca gtgctggggc 850

 tcgggggcct gcggatcagc tctgactctt cctcggacat cgagtctgac 900

 cttgaccgag accccaatag tgcaacagac tcggatggta gtccgctgtc 950

 caacagccag ccttccttcc cagtggagat cttgcccttc ctctacttgg 1000

 gctgtgccaa agactccacc aacttggacg tgttggagga attcggcatc 1050

 aagtacatct tgaacgtcac ccccaatttg ccgaatctct ttgagaacgc 1100

 aggagagttt aaatacaagc aaatccccat ctcggatcac tggagccaaa 1150

 acctgtccca gtttttccct gaggccattt ctttcataga tgaagcccgg 1200

 ggcaagaact gtggtgtctt ggtacattgc ttggctggca ttagccgctc 1250

 agtcactgtg actgtggctt accttatgca gaagctcaat ctgtcgatga 1300

 acgatgccta tgacattgtc aaaatgaaaa aatccaacat atcccctaac 1350

 ttcaacttca tgggtcagct gctggacttc gagaggacgc tgggactcag 1400

 cagcccatgt gacaacaggg ttccagcaca gcagctgtat tttaccaccc 1450

 cttccaacca gaatgtatac caggtggact ctctgcaatc tacgtgaaag 1500

 accccacacc cctccttgct ggaatgtgtc tggcccttca gcagtttctc 1550

 ttggcagcat cagctgggct gctttctttg tgtgtggccc caggtgtcaa 1600

 aatgacacca gctgtctgta ctagacaagg ttaccaagtg cggaattggt 1650

 taatactaac agagagattt gctccattct ctttggaata acaggacatg 1700

 ctgtatagat acaggcagta ggtttgctct gtacccatgt gtacagccta 1750

 cccatgcagg gactgggatt cgaggacttc caggcgcata gggtagaacc 1800

 aaatgatagg gtaggagcat gtgttcttta gggccttgta aggctgtttc 1850

 cttttgcatc tggaactgac tatataattg tcttcaagtg aagactaatt 1900

 caattttgca tatagaggag ccaaagagag atttcagctc tgtatttgtg 1950

 gtatcagtgt tggaaaagag aaatctgata ctccatttgg attattgtaa 2000

 atatttgatc ttgaatcact tgacagtgtt tgtttgaatt gtgtttgttt 2050

 tttcctttga tgggcttaaa agaaattatc caaagggaga aagagcagta 2100

 tgccacttct taaaacagaa caaaacaaaa aaagaaaatt gtgctctgtt 2150

 gtaatccaaa ggggagattt gcagcatgct tgactttacc aattctgatg 2200

 acatctttac ggacactatt atcactaaga ccttgttatg gcgaagtctt 2250

 tagtcttttt catgtatttt cctcatgatt ttttctcttt atgtagtttg 2300

 agtatgcctt acctttgtaa atatttttgc ttgtgttgtc gcaaagggga 2350

 taatctggga aagacaccaa atcatgggct cactttaaaa 2390

<210> 1850
<211> 381
<212> PRT
<213> Homo sapien

<400> 1850
 Met Ile Asp Thr Leu Arg Pro Val Pro Phe Ala Ser Glu Met Ala
   1               5                  10                  15

 Ile Ser Lys Thr Val Ala Trp Leu Asn Glu Gln Leu Glu Leu Gly
                  20                  25                  30

 Asn Glu Arg Leu Leu Leu Met Asp Cys Arg Pro Gln Glu Leu Tyr
                  35                  40                  45

 Glu Ser Ser His Ile Glu Ser Ala Ile Asn Val Ala Ile Pro Gly
                  50                  55                  60

 Ile Met Leu Arg Arg Leu Gln Lys Gly Asn Leu Pro Val Arg Ala
                  65                  70                  75

 Leu Phe Thr Arg Gly Glu Asp Arg Asp Arg Phe Thr Arg Arg Cys
                  80                  85                  90

 Gly Thr Asp Thr Val Val Leu Tyr Asp Glu Ser Ser Ser Asp Trp
                  95                 100                 105

 Asn Glu Asn Thr Gly Gly Glu Ser Leu Leu Gly Leu Leu Leu Lys
                 110                 115                 120

 Lys Leu Lys Asp Glu Gly Cys Arg Ala Phe Tyr Leu Glu Gly Gly
                 125                 130                 135

 Phe Ser Lys Phe Gln Ala Glu Phe Ser Leu His Cys Glu Thr Asn
                 140                 145                 150

 Leu Asp Gly Ser Cys Ser Ser Ser Ser Pro Pro Leu Pro Val Leu
                 155                 160                 165

 Gly Leu Gly Gly Leu Arg Ile Ser Ser Asp Ser Ser Ser Asp Ile
                 170                 175                 180

 Glu Ser Asp Leu Asp Arg Asp Pro Asn Ser Ala Thr Asp Ser Asp
                 185                 190                 195

 Gly Ser Pro Leu Ser Asn Ser Gln Pro Ser Phe Pro Val Glu Ile
                 200                 205                 210

 Leu Pro Phe Leu Tyr Leu Gly Cys Ala Lys Asp Ser Thr Asn Leu
                 215                 220                 225

 Asp Val Leu Glu Glu Phe Gly Ile Lys Tyr Ile Leu Asn Val Thr
                 230                 235                 240

 Pro Asn Leu Pro Asn Leu Phe Glu Asn Ala Gly Glu Phe Lys Tyr
                 245                 250                 255

 Lys Gln Ile Pro Ile Ser Asp His Trp Ser Gln Asn Leu Ser Gln
                 260                 265                 270

 Phe Phe Pro Glu Ala Ile Ser Phe Ile Asp Glu Ala Arg Gly Lys
                 275                 280                 285

 Asn Cys Gly Val Leu Val His Cys Leu Ala Gly Ile Ser Arg Ser
                 290                 295                 300

 Val Thr Val Thr Val Ala Tyr Leu Met Gln Lys Leu Asn Leu Ser
                 305                 310                 315

 Met Asn Asp Ala Tyr Asp Ile Val Lys Met Lys Lys Ser Asn Ile
                 320                 325                 330

 Ser Pro Asn Phe Asn Phe Met Gly Gln Leu Leu Asp Phe Glu Arg
                 335                 340                 345

 Thr Leu Gly Leu Ser Ser Pro Cys Asp Asn Arg Val Pro Ala Gln
                 350                 355                 360

 Gln Leu Tyr Phe Thr Thr Pro Ser Asn Gln Asn Val Tyr Gln Val
                 365                 370                 375

 Asp Ser Leu Gln Ser Thr
                 380

<210> 1851
<211> 1952
<212> DNA
<213> Homo sapien

<400> 1851
 ccagcctcgg agggagggat tagaagccgc tagacttttt ttcctcccct 50

 ctcagtagca cggagtccga attaattgga tttcattcac tggggaggaa 100

 caaaaactat ctgggcagct tcattgagag agattcattg acactaagag 150

 ccagcgctgc agctggtgca gagagaacct ccggctttga cttctgtctc 200

 gtctgcccca aggccgctag cctcggcttg ggaaggcgag gcggaattaa 250

 accccgctcc gagagcgcac gttcgcgcgc ggtgcgtcgg ccattgcctg 300

 ccccgagggg cgtctggtag gcaccccgcc ctctcccgca gctcgacccc 350

 catgatagat acgctcagac ccgtgccctt cgcgtcggaa atggcgatca 400

 gcaagacggt ggcgtggctc aacgagcagc tggagctggg caacgagcgg 450

 ctgctgctga tggactgccg gccgcaggag ctatacgagt cgtcgcacat 500

 cgagtcggcc atcaacgtgg ccatcccggg catcatgctg cggcgcctgc 550

 agaagggtaa cctgccggtg cgcgcgctct tcacgcgcgg cgaggaccgg 600

 gaccgcttca cccggcgctg tggcaccgac acagtggtgc tctacgacga 650

 gagcagcagc gactggaacg agaatacggg cggcgagtcg ttgctcgggc 700

 tgctgctcaa gaagctcaag gacgagggct gccgggcgtt ctacctggaa 750

 gatgaagccc ggggcaagaa ctgtggtgtc ttggtacatt gcttggctgg 800

 cattagccgc tcagtcactg tgactgtggc ttaccttatg cagaagctca 850

 atctgtcgat gaacgatgcc tatgacattg tcaaaatgaa aaaatccaac 900

 atatccccta acttcaactt catgggtcag ctgctggact tcgagaggac 950

 gctgggactc agcagcccat gtgacaacag ggttccagca cagcagctgt 1000

 attttaccac cccttccaac cagaatgtat accaggtgga ctctctgcaa 1050

 tctacgtgaa agaccccaca cccctccttg ctggaatgtg tctggccctt 1100

 cagcagtttc tcttggcagc atcagctggg ctgctttctt tgtgtgtggc 1150

 cccaggtgtc aaaatgacac cagctgtctg tactagacaa ggttaccaag 1200

 tgcggaattg gttaatacta acagagagat ttgctccatt ctctttggaa 1250

 taacaggaca tgctgtatag atacaggcag taggtttgct ctgtacccat 1300

 gtgtacagcc tacccatgca gggactggga ttcgaggact tccaggcgca 1350

 tagggtagaa ccaaatgata gggtaggagc atgtgttctt tagggccttg 1400

 taaggctgtt tccttttgca tctggaactg actatataat tgtcttcaag 1450

 tgaagactaa ttcaattttg catatagagg agccaaagag agatttcagc 1500

 tctgtatttg tggtatcagt gttggaaaag agaaatctga tactccattt 1550

 ggattattgt aaatatttga tcttgaatca cttgacagtg tttgtttgaa 1600

 ttgtgtttgt tttttccttt gatgggctta aaagaaatta tccaaaggga 1650

 gaaagagcag tatgccactt cttaaaacag aacaaaacaa aaaaagaaaa 1700

 ttgtgctctg ttgtaatcca aaggggagat ttgcagcatg cttgacttta 1750

 ccaattctga tgacatcttt acggacacta ttatcactaa gaccttgtta 1800

 tggcgaagtc tttagtcttt ttcatgtatt ttcctcatga ttttttctct 1850

 ttatgtagtt tgagtatgcc ttacctttgt aaatattttt gcttgtgttg 1900

 tcgcaaaggg gataatctgg gaaagacacc aaatcatggg ctcactttaa 1950

 aa 1952

<210> 1852
<211> 235
<212> PRT
<213> Homo sapien

<400> 1852
 Met Ile Asp Thr Leu Arg Pro Val Pro Phe Ala Ser Glu Met Ala
   1               5                  10                  15

 Ile Ser Lys Thr Val Ala Trp Leu Asn Glu Gln Leu Glu Leu Gly
                  20                  25                  30

 Asn Glu Arg Leu Leu Leu Met Asp Cys Arg Pro Gln Glu Leu Tyr
                  35                  40                  45

 Glu Ser Ser His Ile Glu Ser Ala Ile Asn Val Ala Ile Pro Gly
                  50                  55                  60

 Ile Met Leu Arg Arg Leu Gln Lys Gly Asn Leu Pro Val Arg Ala
                  65                  70                  75

 Leu Phe Thr Arg Gly Glu Asp Arg Asp Arg Phe Thr Arg Arg Cys
                  80                  85                  90

 Gly Thr Asp Thr Val Val Leu Tyr Asp Glu Ser Ser Ser Asp Trp
                  95                 100                 105

 Asn Glu Asn Thr Gly Gly Glu Ser Leu Leu Gly Leu Leu Leu Lys
                 110                 115                 120

 Lys Leu Lys Asp Glu Gly Cys Arg Ala Phe Tyr Leu Glu Asp Glu
                 125                 130                 135

 Ala Arg Gly Lys Asn Cys Gly Val Leu Val His Cys Leu Ala Gly
                 140                 145                 150

 Ile Ser Arg Ser Val Thr Val Thr Val Ala Tyr Leu Met Gln Lys
                 155                 160                 165

 Leu Asn Leu Ser Met Asn Asp Ala Tyr Asp Ile Val Lys Met Lys
                 170                 175                 180

 Lys Ser Asn Ile Ser Pro Asn Phe Asn Phe Met Gly Gln Leu Leu
                 185                 190                 195

 Asp Phe Glu Arg Thr Leu Gly Leu Ser Ser Pro Cys Asp Asn Arg
                 200                 205                 210

 Val Pro Ala Gln Gln Leu Tyr Phe Thr Thr Pro Ser Asn Gln Asn
                 215                 220                 225

 Val Tyr Gln Val Asp Ser Leu Gln Ser Thr
                 230                 235

<210> 1853
<211> 1237
<212> DNA
<213> Homo sapien

<400> 1853
 attcttgtct gttctgcctc actcccgagc tctactgact cccaaaagag 50

 cgcccaagaa gaaaatggcc ataagtggag tccctgtgct aggatttttc 100

 atcatagctg tgctgatgag cgctcaggaa tcatgggcta tcaaagaaga 150

 acatgtgatc atccaggccg agttctatct gaatcctgac caatcaggcg 200

 agtttatgtt tgactttgat ggtgatgaga ttttccatgt ggatatggca 250

 aagaaggaga cggtctggcg gcttgaagaa tttggacgat ttgccagctt 300

 tgaggctcaa ggtgcattgg ccaacatagc tgtggacaaa gccaacctgg 350

 aaatcatgac aaagcgctcc aactatactc cgatcaccaa tgtacctcca 400

 gaggtaactg tgctcacgaa cagccctgtg gaactgagag agcccaacgt 450

 cctcatctgt ttcatcgaca agttcacccc accagtggtc aatgtcacgt 500

 ggcttcgaaa tggaaaacct gtcaccacag gagtgtcaga gacagtcttc 550

 ctgcccaggg aagaccacct tttccgcaag ttccactatc tccccttcct 600

 gccctcaact gaggacgttt acgactgcag ggtggagcac tggggcttgg 650

 atgagcctct tctcaagcac tgggagtttg atgctccaag ccctctccca 700

 gagactacag agaacgtggt gtgtgccctg ggcctgactg tgggtctggt 750

 gggcatcatt attgggacca tcttcatcat caagggagtg cgcaaaagca 800

 atgcagcaga acgcaggggg cctctgtaag gcacatggag gtgatgatgt 850

 ttcttagaga gaagatcact gaagaaactt ctgctttaat gactttacaa 900

 agctggcaat attacaatcc ttgacctcag tgaaagcagt catcttcagc 950

 gttttccagc cctatagcca ccccaagtgt ggttatgcct cctcgattgc 1000

 tccgtactct aacatctagc tggctttccc tgtctattgc cttttcctgt 1050

 atctattttc ctctatttcc tatcatttta ttatcaccat gcaatgcctc 1100

 tggaataaaa catacaggag tctgtctctg ctatggaatg ccccatgggg 1150

 ctctcttgtg tacttattgt ttaaggtttc ctcaaactgt gatttttctg 1200

 aacacaataa actattttga tgatcttggg tggaaaa 1237

<210> 1854
<211> 254
<212> PRT
<213> Homo sapien

<400> 1854
 Met Ala Ile Ser Gly Val Pro Val Leu Gly Phe Phe Ile Ile Ala
   1               5                  10                  15

 Val Leu Met Ser Ala Gln Glu Ser Trp Ala Ile Lys Glu Glu His
                  20                  25                  30

 Val Ile Ile Gln Ala Glu Phe Tyr Leu Asn Pro Asp Gln Ser Gly
                  35                  40                  45

 Glu Phe Met Phe Asp Phe Asp Gly Asp Glu Ile Phe His Val Asp
                  50                  55                  60

 Met Ala Lys Lys Glu Thr Val Trp Arg Leu Glu Glu Phe Gly Arg
                  65                  70                  75

 Phe Ala Ser Phe Glu Ala Gln Gly Ala Leu Ala Asn Ile Ala Val
                  80                  85                  90

 Asp Lys Ala Asn Leu Glu Ile Met Thr Lys Arg Ser Asn Tyr Thr
                  95                 100                 105

 Pro Ile Thr Asn Val Pro Pro Glu Val Thr Val Leu Thr Asn Ser
                 110                 115                 120

 Pro Val Glu Leu Arg Glu Pro Asn Val Leu Ile Cys Phe Ile Asp
                 125                 130                 135

 Lys Phe Thr Pro Pro Val Val Asn Val Thr Trp Leu Arg Asn Gly
                 140                 145                 150

 Lys Pro Val Thr Thr Gly Val Ser Glu Thr Val Phe Leu Pro Arg
                 155                 160                 165

 Glu Asp His Leu Phe Arg Lys Phe His Tyr Leu Pro Phe Leu Pro
                 170                 175                 180

 Ser Thr Glu Asp Val Tyr Asp Cys Arg Val Glu His Trp Gly Leu
                 185                 190                 195

 Asp Glu Pro Leu Leu Lys His Trp Glu Phe Asp Ala Pro Ser Pro
                 200                 205                 210

 Leu Pro Glu Thr Thr Glu Asn Val Val Cys Ala Leu Gly Leu Thr
                 215                 220                 225

 Val Gly Leu Val Gly Ile Ile Ile Gly Thr Ile Phe Ile Ile Lys
                 230                 235                 240

 Gly Val Arg Lys Ser Asn Ala Ala Glu Arg Arg Gly Pro Leu
                 245                 250

<210> 1855
<211> 3990
<212> DNA
<213> Homo sapien

<400> 1855
 ggacgtccgg cttcggagcg ggagtgttcg ttgtgccagc gactaaaaag 50

 agaattaaat atgggtgatg ttgagaaagg caagaagatt tttattatga 100

 agtgttccca gtgccacacc gttgaaaagg gaggcaagca caagactggg 150

 ccaaatctcc atggtctctt tgggcggaag acaggtcagg cccctggata 200

 ctcttacaca gccgccaata agaacaaagg catcatctgg ggagaggata 250

 cactgatgga gtatttggag aatcccaaga agtacatccc tggaacaaaa 300

 atgatctttg tcggcattaa gaagaaggaa gaaagggcag acttaatagc 350

 ttatctcaaa aaagctacta atgagtaata attggccact gccttattta 400

 ttacaaaaca gaaatgtctc atgacttttt tatgtgtacc atcctttaat 450

 agatctcata caccagaatt cagatcatga atgactgaca gaatattttg 500

 ttgggcagtc ctgatttaaa actaagactg gcttgtggtt aaatgaatat 550

 gttcagtttt tgaattttaa tagtaactcc aattcagtaa atggtatcac 600

 tgtttacccc ttttaaagat atgattagac ttcgttagta atgttcaact 650

 tttcacaaag atggtgagtg ccatcttaaa acttactgga gattggtttt 700

 atatttagat ttatataact ggttatgtga atatatttaa atactgggga 750

 aattgcttca ctgtcttaga accaagcaag attcacctgt gttttgtgtt 800

 catgttcatt tgcctcttaa aggcaagggt tgaagataaa taaggttgca 850

 atgtctatag ttttggcctt aactatgcca atctaattat aattccctgt 900

 atttaaaatg gtttctttta cttattgaaa ggcattttag tgtggtttat 950

 gtgtaatatt aaagattatt caacacctct cacatcttac agatctataa 1000

 ggtcacatgc ttttaaaata gtagcaagtt aaacttcact cttgaattct 1050

 ttacaatcta agtcaaacta agttataatt taggattgtc tttaaacagc 1100

 cattcagaaa caaaactgta gaactgtgta tttgattggg aatggtgctt 1150

 ttgccaactt aaaaggatta aagtaacgga gatatacaca aattttaaaa 1200

 ttatgtgtga tcacaagact aaagataatt aaaaagaaaa ccacagatca 1250

 tgactttttg actgtgcttg atttcatgac tgatgcacaa attttaatga 1300

 ttaaaaagtg caggagccct aaatgtcagt gcagcagccc taaatgtcag 1350

 tgcagcagtg ttaaccagtc atggtgctag attgtttact tggttttcta 1400

 ggactgcctc aactagaata acacttcact aattgactct tagtttcttt 1450

 gctcagattg agaactgcag catttatgcc agacatggac agaggaatgc 1500

 ctgtggtcat agttttgtga tgtgtaacag tgtataatta catactgaat 1550

 tatttcatgc atagtctgtg ccatacacat ttagagtagt ccttggagat 1600

 tttatggaga tggtgagcac aaggtaagtc ataaagaata atgagaaaat 1650

 aaatctatgc tggtgcagct gagaactgta tctttgtggg acagtgagaa 1700

 gactgagaag atgtgaatcc atggtctcaa aggtgatagg gacgattaga 1750

 taggtgtttt aaggcctgaa agcaatttat aacatatgag tcttattttt 1800

 atttatagaa atgtggaaag cttgctgtaa ttcatatttg aagtcctagt 1850

 ctgagttctg gtggggaatt taaaaatgca tcctggaaat cctttaaaga 1900

 tttcagactt tgaaaggcct tgtagcagag gacttggtga ctgtataaag 1950

 ttagtggtat tcagggacag tgtagcaagt agcttacaag gggacaattc 2000

 tggactaatg agaaagacct gaagtgaagg ctagagagtt gatttttttt 2050

 ttttttggca tcctggaaat gatacaggaa acatattaag atagatacag 2100

 aaatgtgttc aaccttccat cttggctagt tgtggcgttt agtttgtttt 2150

 ttgagacatg gtcacgctgt gtcgccaagg ctggagtgca gtggtgcgat 2200

 ctcggctggc tgcagcctct atttcccagg ctcaagcgat tctctcactt 2250

 cagcttccca agtagctggg actgcgggtg ttcgccacca tgcccagcta 2300

 atttttttgt agagatggag ttttgccatg tggtcccagg ctggtctcaa 2350

 actcctgagc tcaagcaatc cgtccacttg ccttggctcc ccaaagtgct 2400

 gggattgcag gcgtgagcca ccaggccctg cctggttttc aaattcagaa 2450

 atcttattat ttaacccaga agtaatcagc ccagtagtaa cttaggttta 2500

 attttttttc aggtttaaaa tttttctcat ttattttttc tgagacggag 2550

 tttcgccctt ttcgcccagg ctgagtacag tggtgcaatc tcactgcaac 2600

 ctccgccttc cagttgcaag tgattctcct gcctcagcct cctgagtagc 2650

 tgggattgca ggcacccgcc accacgcctg gctaattttt gtatttttag 2700

 tggagatggt gtttcaccat gttggccaga ctggtcttgg actcctgacc 2750

 tcgtgatcca cccaccttgg cctcccaaag ttctaggatt acaggtgtga 2800

 gccaccacgt ccggccaatt tttctcattt ctatgcctcc tatattaagg 2850

 tctgtgttgg cacagatgag taactgccat gttctaggtc agttataccc 2900

 aagcacttct ggtggtttaa aatgtgattc tgtaactttt ttatttttat 2950

 ttttttgaga taatttcact cttgttgccc aggctggagt gcaatggcgt 3000

 gatcgctgct caccgcaacc tccgccttcc aggttcaagc gattctcctg 3050

 actcagcctc tcaagtagct gggattacaa gcatgcgcca ccatgcccag 3100

 cttattttgt gtttttagta gagacagggt ttctccatgc tggacaggct 3150

 ggtcttgaac tcccgacgtc gggtgatctg cctgcctcgg cctcccaaag 3200

 tgctgggatt acaggcgtga gccaccacgc ctggccaatt atgtaatttt 3250

 ttaaaaagga catttctatc agggatatat accttcagaa ataaggaaat 3300

 aggggaaaaa aagagcacta taaaccacat gttttcattt ctagtgcttc 3350

 gctgtaagtg gctaggttgg tagaatcaaa aacaagggcc agatgtattt 3400

 aaggggtatt cagatgccac ctacatgctt attttgtcta gaacagtgct 3450

 gtctaataga actttctgtg acgatggata ttttgtagac ttttgctgtc 3500

 cagtgtggta gccactaacc acatgtggct gttaagccct tgaaatatag 3550

 ctagtgtgac tagaaagtat tttattttaa atttacatag gcacaagtgg 3600

 ctagtggcta ctgtattgac attctgggtc taggactaga accagtggtc 3650

 tgtaacaaaa gtactttctc tttactctat taaatctaga attagccggg 3700

 catggtcgct catgcctgtg gtcccagcac tttgggaggc caaggcaggc 3750

 agatcacttg aggtcgggcg tttgagacca gcctggtcaa catggcgaaa 3800

 ccctgtctct acaaaaaaca taaaagttag ccaggtgtgg tggtgggcac 3850

 ctgtagtctc agctacttgg gaggctgagg cacaagaatc acttgaactt 3900

 gggaggtgga ggttgcagtg agccaggatt gtgccactgc actcaagcct 3950

 gggtgacgag tgaaactgtc tccaaaaaaa aaaaaaaaaa 3990

<210> 1856
<211> 105
<212> PRT
<213> Homo sapien

<400> 1856
 Met Gly Asp Val Glu Lys Gly Lys Lys Ile Phe Ile Met Lys Cys
   1               5                  10                  15

 Ser Gln Cys His Thr Val Glu Lys Gly Gly Lys His Lys Thr Gly
                  20                  25                  30

 Pro Asn Leu His Gly Leu Phe Gly Arg Lys Thr Gly Gln Ala Pro
                  35                  40                  45

 Gly Tyr Ser Tyr Thr Ala Ala Asn Lys Asn Lys Gly Ile Ile Trp
                  50                  55                  60

 Gly Glu Asp Thr Leu Met Glu Tyr Leu Glu Asn Pro Lys Lys Tyr
                  65                  70                  75

 Ile Pro Gly Thr Lys Met Ile Phe Val Gly Ile Lys Lys Lys Glu
                  80                  85                  90

 Glu Arg Ala Asp Leu Ile Ala Tyr Leu Lys Lys Ala Thr Asn Glu
                  95                 100                 105

<210> 1857
<211> 1163
<212> DNA
<213> Homo sapien

<400> 1857
 ccggcggcgc ctcaggtcgc ggggcgccta ggcctgggtt gtcctttgca 50

 tctgcacgtg ttcgcagtcg tttccgcgat gctgcctctg ctgcgctgcg 100

 tgccccgtgt gctgggctcc tccgtcgccg gcctccgcgc tgccgcgccc 150

 gcctcgcctt tccggcagct cctgcagccg gcaccccggc tgtgcacccg 200

 gcccttcggg ctgctcagcg tgcgcgcagg ttccgagcgg cggccgggcc 250

 tcctgcggcc tcgcggaccc tgcgcctgtg gctgtggctg cggctcgctg 300

 cacaccgacg gagacaaagc ttttgttgat ttcctgagtg atgaaattaa 350

 ggaggaaaga aaaattcaga agcataaaac cctccctaag atgtctggag 400

 gttgggagct ggaactgaat gggacagaag cgaaattagt gcggaaagtt 450

 gccggggaaa aaatcacggt cactttcaac attaacaaca gcatcccacc 500

 aacatttgat ggtgaggagg aaccctcgca agggcagaag gttgaagaac 550

 aggagcctga actgacatca actcccaatt tcgtggttga agttataaag 600

 aatgatgatg gcaagaaggc ccttgtgttg gactgtcatt atccagagga 650

 tgaggttgga caagaagacg aggctgagag tgacatcttc tctatcaggg 700

 aagttagctt tcagtccact ggcgagtctg aatggaagga tactaattat 750

 acactcaaca cagattcctt ggactgggcc ttatatgacc acctaatgga 800

 tttccttgcc gaccgagggg tggacaacac ttttgcagat gagctggtgg 850

 agctcagcac agccctggag caccaggagt acattacttt tcttgaagac 900

 ctcaagagtt ttgtcaagag ccagtagagc agacagatgc tgaaagccat 950

 agtttcatgg caggctttgg ccagtgaaca aatcctactc tgaagctaga 1000

 catgtgcttt gaaatgatta tcatcctaat atcatggggg aaaaaatacc 1050

 aaatttaaat tatatgtttt gtgttctcat ttattatcat ttttttctgt 1100

 acaaatctat tatttctaga tttttgtata acatgataga cataaaattg 1150

 gtttatctcc tcc 1163

<210> 1858
<211> 282
<212> PRT
<213> Homo sapien

<400> 1858
 Met Leu Pro Leu Leu Arg Cys Val Pro Arg Val Leu Gly Ser Ser
   1               5                  10                  15

 Val Ala Gly Leu Arg Ala Ala Ala Pro Ala Ser Pro Phe Arg Gln
                  20                  25                  30

 Leu Leu Gln Pro Ala Pro Arg Leu Cys Thr Arg Pro Phe Gly Leu
                  35                  40                  45

 Leu Ser Val Arg Ala Gly Ser Glu Arg Arg Pro Gly Leu Leu Arg
                  50                  55                  60

 Pro Arg Gly Pro Cys Ala Cys Gly Cys Gly Cys Gly Ser Leu His
                  65                  70                  75

 Thr Asp Gly Asp Lys Ala Phe Val Asp Phe Leu Ser Asp Glu Ile
                  80                  85                  90

 Lys Glu Glu Arg Lys Ile Gln Lys His Lys Thr Leu Pro Lys Met
                  95                 100                 105

 Ser Gly Gly Trp Glu Leu Glu Leu Asn Gly Thr Glu Ala Lys Leu
                 110                 115                 120

 Val Arg Lys Val Ala Gly Glu Lys Ile Thr Val Thr Phe Asn Ile
                 125                 130                 135

 Asn Asn Ser Ile Pro Pro Thr Phe Asp Gly Glu Glu Glu Pro Ser
                 140                 145                 150

 Gln Gly Gln Lys Val Glu Glu Gln Glu Pro Glu Leu Thr Ser Thr
                 155                 160                 165

 Pro Asn Phe Val Val Glu Val Ile Lys Asn Asp Asp Gly Lys Lys
                 170                 175                 180

 Ala Leu Val Leu Asp Cys His Tyr Pro Glu Asp Glu Val Gly Gln
                 185                 190                 195

 Glu Asp Glu Ala Glu Ser Asp Ile Phe Ser Ile Arg Glu Val Ser
                 200                 205                 210

 Phe Gln Ser Thr Gly Glu Ser Glu Trp Lys Asp Thr Asn Tyr Thr
                 215                 220                 225

 Leu Asn Thr Asp Ser Leu Asp Trp Ala Leu Tyr Asp His Leu Met
                 230                 235                 240

 Asp Phe Leu Ala Asp Arg Gly Val Asp Asn Thr Phe Ala Asp Glu
                 245                 250                 255

 Leu Val Glu Leu Ser Thr Ala Leu Glu His Gln Glu Tyr Ile Thr
                 260                 265                 270

 Phe Leu Glu Asp Leu Lys Ser Phe Val Lys Ser Gln
                 275                 280

<210> 1859
<211> 2856
<212> DNA
<213> Homo sapien

<400> 1859
 gtaaccgcta ctcccggaca ccagaccacc gccttccgta cacaggggcc 50

 cgcatcccac cctcccggac ctaagagcct gggtcccctg tttccggagg 100

 tccgcttccc ggcccccaga ttctggcatc ccagccctca gtgtccaaga 150

 cccaggcagc ccgggtcccc gcctcccgga tccaggcgtc cgggatctgc 200

 gccaccagaa cctagcctcc tgcagacctc cgccatctgg gggcactcaa 250

 cctcctggag ccaagggccc cacgtcccac ccagagaaac tctcgtattc 300

 ccagctccta gggccaagga acccgggcgc tccgaactcc cagctttcgg 350

 acatctggca cacggggcag agcagagaag ctcagcgccc agcctgggga 400

 atttaaacac tccagcttcc aagagccaag gaacttcagt gctgtgaact 450

 cacaactcta aggagccctc caaagttcca gtctccaggt gctgttactc 500

 aactcagtcc taggaacgtc gggtcctggg aaggagccca agcgctccca 550

 gccagcttcc aggcgctaag aaaccccggt gcttcccatc atggtggccg 600

 atcctcctcg agactccaag gggctcgcag cggcggagcc caccgccaac 650

 gggggcctgg cgctggcctc catcgaggac caaggcgcgg cagcaggcgg 700

 ctactgcggt tcccgggacc aggtgcgccg ctgccttcga gccaacctgc 750

 ttgtgctgct gacagtggtg gccgtggtgg ccggcgtggc gctgggactg 800

 ggggtgtcgg gggccggggg tgcgctggcg ttgggcccgg agcgcttgag 850

 cgccttcgtc ttcccgggcg agctgctgct gcgtctgctg cggatgatca 900

 tcttgccgct ggtggtgtgc agcttgatcg gcggcgccgc cagcctggac 950

 cccggcgcgc tcggccgtct gggcgcctgg gcgctgctct ttttcctggt 1000

 caccacgctg ctggcgtcgg cgctcggagt gggcttggcg ctggctctgc 1050

 agccgggcgc cgcctccgcc gccatcaacg cctccgtggg agccgcgggc 1100

 agtgccgaaa atgcccccag caaggaggtg ctcgattcgt tcctggatct 1150

 tgcgagaaat atcttccctt ccaacctggt gtcagcagcc tttcgctcat 1200

 actctaccac ctatgaagag aggaatatca ccggaaccag ggtgaaggtg 1250

 cccgtggggc aggaggtgga ggggatgaac atcctgggct tggtagtgtt 1300

 tgccatcgtc tttggtgtgg cgctgcggaa gctggggcct gaaggggagc 1350

 tgcttatccg cttcttcaac tccttcaatg aggccaccat ggttctggtc 1400

 tcctggatca tgtggtacgc ccctgtgggc atcatgttcc tggtggctgg 1450

 caagatcgtg gagatggagg atgtgggttt actctttgcc cgccttggca 1500

 agtacattct gtgctgcctg ctgggtcacg ccatccatgg gctcctggta 1550

 ctgcccctca tctacttcct cttcacccgc aaaaacccct accgcttcct 1600

 gtggggcatc gtgacgccgc tggccactgc ctttgggacc tcttccagtt 1650

 ccgccacgct gccgctgatg atgaagtgcg tggaggagaa taatggcgtg 1700

 gccaagcaca tcagccgttt catcctgccc atcggcgcca ccgtcaacat 1750

 ggacggtgcc gcgctcttcc agtgcgtggc cgcagtgttc attgcacagc 1800

 tcagccagca gtccttggac ttcgtaaaga tcatcaccat cctggtcacg 1850

 gccacagcgt ccagcgtggg ggcagcgggc atccctgctg gaggtgtcct 1900

 cactctggcc atcatcctcg aagcagtcaa cctcccggtc gaccatatct 1950

 ccttgatcct ggctgtggac tggctagtcg accggtcctg taccgtcctc 2000

 aatgtagaag gtgacgctct gggggcagga ctcctccaaa attatgtgga 2050

 ccgtacggag tcgagaagca cagagcctga gttgatacaa gtgaagagtg 2100

 agctgcccct ggatccgctg ccagtcccca ctgaggaagg aaaccccctc 2150

 ctcaaacact atcgggggcc cgcaggggat gccacggtcg cctctgagaa 2200

 ggaatcagtc atgtaaaccc cgggagggac cttccctgcc ctgctggggg 2250

 tgctctttgg acactggatt atgaggaatg gataaatgga tgagctaggg 2300

 ctctgggggt ctgcctgcac actctgggga gccaggggcc ccagcaccct 2350

 ccaggacagg agatctggga tgcctggctg ctggagtaca tgtgttcaca 2400

 agggttactc ctcaaaaccc ccagttctca ctcatgtccc caactcaagg 2450

 ctagaaaaca gcaagatgga gaaataatgt tctgctgcgt ccccaccgtg 2500

 acctgcctgg cctcccctgt ctcagggagc aggtcacagg tcaccatggg 2550

 gaattctagc ccccactggg gggatgttac aacaccatgc tggttatttt 2600

 ggcggctgta gttgtggggg gatgtgtgtg tgcacgtgtg tgtgtgtgtg 2650

 tgtgtgtgtg tgtgtgtgtg ttctgtgacc tcctgtcccc atggtacgtc 2700

 ccaccctgtc cccagatccc ctattccctc cacaataaca gaaacactcc 2750

 cagggactct ggggagaggc tgaggacaaa tacctgctgt cactccagag 2800

 gacatttttt ttagcaataa aattgagtgt caactattta aaaaaaaaaa 2850

 aaaaaa 2856

<210> 1860
<211> 541
<212> PRT
<213> Homo sapien

<400> 1860
 Met Val Ala Asp Pro Pro Arg Asp Ser Lys Gly Leu Ala Ala Ala
   1               5                  10                  15

 Glu Pro Thr Ala Asn Gly Gly Leu Ala Leu Ala Ser Ile Glu Asp
                  20                  25                  30

 Gln Gly Ala Ala Ala Gly Gly Tyr Cys Gly Ser Arg Asp Gln Val
                  35                  40                  45

 Arg Arg Cys Leu Arg Ala Asn Leu Leu Val Leu Leu Thr Val Val
                  50                  55                  60

 Ala Val Val Ala Gly Val Ala Leu Gly Leu Gly Val Ser Gly Ala
                  65                  70                  75

 Gly Gly Ala Leu Ala Leu Gly Pro Glu Arg Leu Ser Ala Phe Val
                  80                  85                  90

 Phe Pro Gly Glu Leu Leu Leu Arg Leu Leu Arg Met Ile Ile Leu
                  95                 100                 105

 Pro Leu Val Val Cys Ser Leu Ile Gly Gly Ala Ala Ser Leu Asp
                 110                 115                 120

 Pro Gly Ala Leu Gly Arg Leu Gly Ala Trp Ala Leu Leu Phe Phe
                 125                 130                 135

 Leu Val Thr Thr Leu Leu Ala Ser Ala Leu Gly Val Gly Leu Ala
                 140                 145                 150

 Leu Ala Leu Gln Pro Gly Ala Ala Ser Ala Ala Ile Asn Ala Ser
                 155                 160                 165

 Val Gly Ala Ala Gly Ser Ala Glu Asn Ala Pro Ser Lys Glu Val
                 170                 175                 180

 Leu Asp Ser Phe Leu Asp Leu Ala Arg Asn Ile Phe Pro Ser Asn
                 185                 190                 195

 Leu Val Ser Ala Ala Phe Arg Ser Tyr Ser Thr Thr Tyr Glu Glu
                 200                 205                 210

 Arg Asn Ile Thr Gly Thr Arg Val Lys Val Pro Val Gly Gln Glu
                 215                 220                 225

 Val Glu Gly Met Asn Ile Leu Gly Leu Val Val Phe Ala Ile Val
                 230                 235                 240

 Phe Gly Val Ala Leu Arg Lys Leu Gly Pro Glu Gly Glu Leu Leu
                 245                 250                 255

 Ile Arg Phe Phe Asn Ser Phe Asn Glu Ala Thr Met Val Leu Val
                 260                 265                 270

 Ser Trp Ile Met Trp Tyr Ala Pro Val Gly Ile Met Phe Leu Val
                 275                 280                 285

 Ala Gly Lys Ile Val Glu Met Glu Asp Val Gly Leu Leu Phe Ala
                 290                 295                 300

 Arg Leu Gly Lys Tyr Ile Leu Cys Cys Leu Leu Gly His Ala Ile
                 305                 310                 315

 His Gly Leu Leu Val Leu Pro Leu Ile Tyr Phe Leu Phe Thr Arg
                 320                 325                 330

 Lys Asn Pro Tyr Arg Phe Leu Trp Gly Ile Val Thr Pro Leu Ala
                 335                 340                 345

 Thr Ala Phe Gly Thr Ser Ser Ser Ser Ala Thr Leu Pro Leu Met
                 350                 355                 360

 Met Lys Cys Val Glu Glu Asn Asn Gly Val Ala Lys His Ile Ser
                 365                 370                 375

 Arg Phe Ile Leu Pro Ile Gly Ala Thr Val Asn Met Asp Gly Ala
                 380                 385                 390

 Ala Leu Phe Gln Cys Val Ala Ala Val Phe Ile Ala Gln Leu Ser
                 395                 400                 405

 Gln Gln Ser Leu Asp Phe Val Lys Ile Ile Thr Ile Leu Val Thr
                 410                 415                 420

 Ala Thr Ala Ser Ser Val Gly Ala Ala Gly Ile Pro Ala Gly Gly
                 425                 430                 435

 Val Leu Thr Leu Ala Ile Ile Leu Glu Ala Val Asn Leu Pro Val
                 440                 445                 450

 Asp His Ile Ser Leu Ile Leu Ala Val Asp Trp Leu Val Asp Arg
                 455                 460                 465

 Ser Cys Thr Val Leu Asn Val Glu Gly Asp Ala Leu Gly Ala Gly
                 470                 475                 480

 Leu Leu Gln Asn Tyr Val Asp Arg Thr Glu Ser Arg Ser Thr Glu
                 485                 490                 495

 Pro Glu Leu Ile Gln Val Lys Ser Glu Leu Pro Leu Asp Pro Leu
                 500                 505                 510

 Pro Val Pro Thr Glu Glu Gly Asn Pro Leu Leu Lys His Tyr Arg
                 515                 520                 525

 Gly Pro Ala Gly Asp Ala Thr Val Ala Ser Glu Lys Glu Ser Val
                 530                 535                 540

 Met


<210> 1861
<211> 2264
<212> DNA
<213> Homo sapien

<400> 1861
 ggcacgaggg agcgcttggg agttaggttg tttgccggcg tagcggccag 50

 cgcctgagcc cgccgttgat cttcgctgtg gcatggcgga cgaggggaag 100

 tcgtacagcg aacacgatga tgaacgcgtt aatttccctc aaagaaagaa 150

 gaaaggccgg ggtcccttcc ggtggaaata tggtgaagga aaccgtaggt 200

 ctggaagagg cggttctggt attcggtctt cccgccttga ggaagatgat 250

 ggagatgtgg caatgagtga tgcccaggat ggtccccgag tacgatacaa 300

 cccctatacc acccgaccta accgtcgggg tgatacttgg catgatcgag 350

 atcgcattca tgttactgtg cggagagaca gagctcctcc agagagagga 400

 ggggctggca ccagccagga tgggacctca aagaactggt tcaagattac 450

 aattccttat ggcagaaagt atgacaaggc atggctcctg agcatgattc 500

 agagcaagtg cagtgtgccc ttcaccccta ttgagtttca ctatgagaat 550

 acacgggccc agttcttcgt tgaagacgcc agtactgcct ctgcattgaa 600

 ggctgtcaac tataagattt tggatcggga gaaccgaagg atatctatca 650

 tcatcaactc ttctgctcca ccccacacta tactgaatga actgaagcca 700

 gaacaagtag aacagctaaa gctgatcatg agcaaacgat acgatggctc 750

 ccaacaagcc cttgacctca aaggcctccg ttcagaccca gatttggtgg 800

 cccagaacat tgacgttgtc ctgaatcgca gaagctgtat ggcagctacc 850

 ctgaggatca ttgaagagaa catccctgag ctattgtcct tgaacttgag 900

 caacaacagg ctgtacaggc tggatgacat gtctagcatt gttcagaagg 950

 cacccaacct gaagatccta aacctttctg gaaatgaatt gaagtctgag 1000

 cgggaattgg acaagataaa ggggctgaag ctagaagagc tctggctcga 1050

 tggaaactcc ctgtgtgaca ccttccgaga ccagtccacc tacatcagcg 1100

 ccattcgcga acgatttccc aagttactac gcctggatgg ccatgagcta 1150

 cccccaccaa ttgcctttga tgttgaagcc cccacgacgt taccgccctg 1200

 caagggaagc tattttggaa cagaaaactt gaagagtctg gtcttgcact 1250

 tcctgcaaca gtactatgca atttacgact ctggagaccg acaagggctc 1300

 ctggatgcct accatgatgg ggcctgctgt tccctgagca ttcctttcat 1350

 tcctcagaac cctgcccgaa gcagcttagc cgagtatttc aaggatagca 1400

 gaaatgtgaa gaagcttaaa gaccctacct tgcggttccg gctgctgaag 1450

 cacacgcgtc tcaacgttgt tgccttcctc aatgagttgc ccaaaaccca 1500

 gcacgacgtc aattccttcg tggtagacat aagcgcccag acaagcacat 1550

 tgctgtgttt ttctgtcaat ggagtcttca aggaagtgga cggaaagtcc 1600

 cgggattctt tgcgagcctt cacccggaca ttcattgctg ttcctgctag 1650

 caattcaggg ctatgtattg taaatgatga gctatttgtg cggaatgcca 1700

 gttctgaaga gatccaaaga gccttcgcta tgcctgcacc cacgccttcc 1750

 tccagcccgg tgcccaccct ctctccagag cagcaggaaa tgttgcaagc 1800

 attctctacc cagtctggca tgaacctcga gtggtcccag aagtgccttc 1850

 aggacaacaa ctgggactac accagatctg cccaggcctt cactcatctc 1900

 aaggccaagg gcgagatccc agaagtggca ttcatgaagt gatcgtagtc 1950

 atgcctcaga agcagtcccc cctgtaaata gtccttggat attaccgtct 2000

 ggttgtcgtc tgtcatctcc tcctgtctgg cccgaggccg ccccgtgact 2050

 gtgaccgagg gagggagggc tgcctgatcc ctctcctcgc ctgccttctg 2100

 gaagacttca gaagattgag cctcactggt gccaggaagc caaagcttac 2150

 tttgtagaac tgacactaaa ctacccgaag gacttaggtg ctttgtgtac 2200

 ttaaccccag gacctcctta ctttttaata taaagagtga tgttgtaaaa 2250

 aaaaaaaaaa aaaa 2264

<210> 1862
<211> 619
<212> PRT
<213> Homo sapien

<400> 1862
 Met Ala Asp Glu Gly Lys Ser Tyr Ser Glu His Asp Asp Glu Arg
   1               5                  10                  15

 Val Asn Phe Pro Gln Arg Lys Lys Lys Gly Arg Gly Pro Phe Arg
                  20                  25                  30

 Trp Lys Tyr Gly Glu Gly Asn Arg Arg Ser Gly Arg Gly Gly Ser
                  35                  40                  45

 Gly Ile Arg Ser Ser Arg Leu Glu Glu Asp Asp Gly Asp Val Ala
                  50                  55                  60

 Met Ser Asp Ala Gln Asp Gly Pro Arg Val Arg Tyr Asn Pro Tyr
                  65                  70                  75

 Thr Thr Arg Pro Asn Arg Arg Gly Asp Thr Trp His Asp Arg Asp
                  80                  85                  90

 Arg Ile His Val Thr Val Arg Arg Asp Arg Ala Pro Pro Glu Arg
                  95                 100                 105

 Gly Gly Ala Gly Thr Ser Gln Asp Gly Thr Ser Lys Asn Trp Phe
                 110                 115                 120

 Lys Ile Thr Ile Pro Tyr Gly Arg Lys Tyr Asp Lys Ala Trp Leu
                 125                 130                 135

 Leu Ser Met Ile Gln Ser Lys Cys Ser Val Pro Phe Thr Pro Ile
                 140                 145                 150

 Glu Phe His Tyr Glu Asn Thr Arg Ala Gln Phe Phe Val Glu Asp
                 155                 160                 165

 Ala Ser Thr Ala Ser Ala Leu Lys Ala Val Asn Tyr Lys Ile Leu
                 170                 175                 180

 Asp Arg Glu Asn Arg Arg Ile Ser Ile Ile Ile Asn Ser Ser Ala
                 185                 190                 195

 Pro Pro His Thr Ile Leu Asn Glu Leu Lys Pro Glu Gln Val Glu
                 200                 205                 210

 Gln Leu Lys Leu Ile Met Ser Lys Arg Tyr Asp Gly Ser Gln Gln
                 215                 220                 225

 Ala Leu Asp Leu Lys Gly Leu Arg Ser Asp Pro Asp Leu Val Ala
                 230                 235                 240

 Gln Asn Ile Asp Val Val Leu Asn Arg Arg Ser Cys Met Ala Ala
                 245                 250                 255

 Thr Leu Arg Ile Ile Glu Glu Asn Ile Pro Glu Leu Leu Ser Leu
                 260                 265                 270

 Asn Leu Ser Asn Asn Arg Leu Tyr Arg Leu Asp Asp Met Ser Ser
                 275                 280                 285

 Ile Val Gln Lys Ala Pro Asn Leu Lys Ile Leu Asn Leu Ser Gly
                 290                 295                 300

 Asn Glu Leu Lys Ser Glu Arg Glu Leu Asp Lys Ile Lys Gly Leu
                 305                 310                 315

 Lys Leu Glu Glu Leu Trp Leu Asp Gly Asn Ser Leu Cys Asp Thr
                 320                 325                 330

 Phe Arg Asp Gln Ser Thr Tyr Ile Ser Ala Ile Arg Glu Arg Phe
                 335                 340                 345

 Pro Lys Leu Leu Arg Leu Asp Gly His Glu Leu Pro Pro Pro Ile
                 350                 355                 360

 Ala Phe Asp Val Glu Ala Pro Thr Thr Leu Pro Pro Cys Lys Gly
                 365                 370                 375

 Ser Tyr Phe Gly Thr Glu Asn Leu Lys Ser Leu Val Leu His Phe
                 380                 385                 390

 Leu Gln Gln Tyr Tyr Ala Ile Tyr Asp Ser Gly Asp Arg Gln Gly
                 395                 400                 405

 Leu Leu Asp Ala Tyr His Asp Gly Ala Cys Cys Ser Leu Ser Ile
                 410                 415                 420

 Pro Phe Ile Pro Gln Asn Pro Ala Arg Ser Ser Leu Ala Glu Tyr
                 425                 430                 435

 Phe Lys Asp Ser Arg Asn Val Lys Lys Leu Lys Asp Pro Thr Leu
                 440                 445                 450

 Arg Phe Arg Leu Leu Lys His Thr Arg Leu Asn Val Val Ala Phe
                 455                 460                 465

 Leu Asn Glu Leu Pro Lys Thr Gln His Asp Val Asn Ser Phe Val
                 470                 475                 480

 Val Asp Ile Ser Ala Gln Thr Ser Thr Leu Leu Cys Phe Ser Val
                 485                 490                 495

 Asn Gly Val Phe Lys Glu Val Asp Gly Lys Ser Arg Asp Ser Leu
                 500                 505                 510

 Arg Ala Phe Thr Arg Thr Phe Ile Ala Val Pro Ala Ser Asn Ser
                 515                 520                 525

 Gly Leu Cys Ile Val Asn Asp Glu Leu Phe Val Arg Asn Ala Ser
                 530                 535                 540

 Ser Glu Glu Ile Gln Arg Ala Phe Ala Met Pro Ala Pro Thr Pro
                 545                 550                 555

 Ser Ser Ser Pro Val Pro Thr Leu Ser Pro Glu Gln Gln Glu Met
                 560                 565                 570

 Leu Gln Ala Phe Ser Thr Gln Ser Gly Met Asn Leu Glu Trp Ser
                 575                 580                 585

 Gln Lys Cys Leu Gln Asp Asn Asn Trp Asp Tyr Thr Arg Ser Ala
                 590                 595                 600

 Gln Ala Phe Thr His Leu Lys Ala Lys Gly Glu Ile Pro Glu Val
                 605                 610                 615

 Ala Phe Met Lys


<210> 1863
<211> 2820
<212> DNA
<213> Homo sapien

<400> 1863
 gggattttta aaaaatcaaa atacaaatcc aactttttga gttttcgttg 50

 tcattgctct tatctttcct gagtcacttc ccattttcca aactcagcaa 100

 ccccagtttg cgagtctggt ttcatgaacc tttgtaaggt gtttggtgcg 150

 gtcacrgtgt atacttgccg tgtagtattt gactcagcgc gatctgcctt 200

 gagtcatttt accgcggcca tttactactg ccgttgagcc ctgtccacgc 250

 cttgggagtg ttgatatgtt gagagttttc tgtctggctg rggagggatc 300

 atttagtttt tgcggacgta tgttgcactg aggatttagg gagagagcaa 350

 gatttctgtt gaggaggttc agaagtataa ggaatcggga gagtagatag 400

 gagtgaagca tttggcagcg taaagaagct tggcttagct ttaatggatt 450

 agggagagat tgctatctag cattattaca tgttattgtt ctctttgcta 500

 ttttatacac ctagaacaac ctttccctcg gggttaacaa acatcttcaa 550

 ctctgttttc tgtatggctc ctgactctta cctttgtttt aggaggcttc 600

 cctcttcaga ggaaactggg agaagccaat ttccactgct tctttttcct 650

 gtgccttttt aacactcaaa cccagaacac ttaatcctct gcagctcgtg 700

 caaaaattca gtctgtaatt taaaatgtgt gcacggtaca ctgctgacca 750

 tgggcatgtc tattgtttgt atctgtaatg tgtatgtcca tttcagtgtt 800

 gtctgtttta gtatgcaggt gatagactag agaacaagac ctctgtctcc 850

 gtagcatcct ggagcagtct gaatgccaga atggataacc gttttgctac 900

 agcatttgta attgcttgtg tgcttagcct catttccacc atctacatgg 950

 cagcctccat tggcacagac ttctggtatg aatatcgaag tccagttcaa 1000

 gaaaattcca gtgatttgaa taaaagcatc tgggatgaat tcattagtga 1050

 tgaggcagat gaaaagactt ataatgatgc actttttcga tacaatggca 1100

 cagtgggatt gtggagacgg tgtatcacca tacccaaaaa catgcattgg 1150

 tatagcccac cagaaaggac agagtcattt gatgtggtca caaaatgtgt 1200

 gagtttcaca ctaactgagc agttcatgga gaaatttgtt gatcccggaa 1250

 accacaatag cgggattgat ctccttagga cctatctttg gcgttgccag 1300

 ttccttttac cttttgtgag tttaggtttg atgtgctttg gggctttgat 1350

 cggactttgt gcttgcattt gccgaagctt atatcccacc attgccacgg 1400

 gcattctcca tctccttgca ggtctgtgta cactgggctc agtaagttgt 1450

 tatgttgctg gaattgaact actccaccag aaactagagc tccctgacaa 1500

 tgtatccggt gaatttggat ggtccttctg cctggcttgt gtctctgctc 1550

 ccttacagtt catggcttct gctctcttca tctgggctgc tcacaccaac 1600

 cggaaagagt acaccttaat gaaggcatat cgtgtggcat gagcaagaaa 1650

 ctgcctgctt tacaattgcc atttttattt ttttaaaata atactgatat 1700

 tttccccacc tctcaattgt ttttaatttt tatttgtgga tataccattt 1750

 tattatgaaa atctatttta tttatacaca ttcaccacta aatacacact 1800

 taataccact aaaatttatg tggtttactt taagcgatgc catctttcaa 1850

 ataaactaat ctaggtctag acagaaagaa atggatagag acttgacaca 1900

 aatttatgaa agaaaattgg gagtaggaat gtgaccgaaa acaagttgtg 1950

 ctaatgtctg ttagactttt cagtaaaact aaagtaactg tatctgttca 2000

 actaaaaact ctatattagt ttctttggga aacctctcat cgtcaaaact 2050

 ttatgttcac tttgctgttg tagatagcca gtcaaccagc agtattagtg 2100

 ctgttttcaa agatttaagc tctataaaat tgggaaatta tctaagatca 2150

 ttttccctaa gcattgacac atagcttcat ctgaggtgag atatggcagc 2200

 tgtttgtatc tgcactgtgt ctgtctacaa aaagtgaaaa atacagtgtt 2250

 tacttgaaat tttaactttg taactgcaag aattccagtt cagccgggcg 2300

 aggattagta ttatttttaa ctctccgtaa gattttcagt accaccaaat 2350

 tgttttggat tttttttctt tcctcttcac ataccagggt tattaaaagt 2400

 gtgctttctt tttacattat attacagtta caaggtaaaa ttcctcaact 2450

 gctatttatt tattccagcc cagtactata aagaacgttt caccataatg 2500

 accctccaga gctgggaaac ctaccacaag atctaaagtt ctggctgtcc 2550

 attaacctcc aactatggtc tttatttctt gtggtaatat gatgtgcctt 2600

 tccttgccta aatcccttcc tggtgtgtat caacattatt taatgtcttc 2650

 taattcagtc atttttttat aagtatgtct ataaacattg aactttaaaa 2700

 aacttattta tttattccac tactgtagca attgacagat taaaaaaatg 2750

 taacttcata atttcttacc ataacctcaa tgtctttttt aaaaaataaa 2800

 attaaaaatg aaaagagaaa 2820

<210> 1864
<211> 253
<212> PRT
<213> Homo sapien

<400> 1864
 Met Asp Asn Arg Phe Ala Thr Ala Phe Val Ile Ala Cys Val Leu
   1               5                  10                  15

 Ser Leu Ile Ser Thr Ile Tyr Met Ala Ala Ser Ile Gly Thr Asp
                  20                  25                  30

 Phe Trp Tyr Glu Tyr Arg Ser Pro Val Gln Glu Asn Ser Ser Asp
                  35                  40                  45

 Leu Asn Lys Ser Ile Trp Asp Glu Phe Ile Ser Asp Glu Ala Asp
                  50                  55                  60

 Glu Lys Thr Tyr Asn Asp Ala Leu Phe Arg Tyr Asn Gly Thr Val
                  65                  70                  75

 Gly Leu Trp Arg Arg Cys Ile Thr Ile Pro Lys Asn Met His Trp
                  80                  85                  90

 Tyr Ser Pro Pro Glu Arg Thr Glu Ser Phe Asp Val Val Thr Lys
                  95                 100                 105

 Cys Val Ser Phe Thr Leu Thr Glu Gln Phe Met Glu Lys Phe Val
                 110                 115                 120

 Asp Pro Gly Asn His Asn Ser Gly Ile Asp Leu Leu Arg Thr Tyr
                 125                 130                 135

 Leu Trp Arg Cys Gln Phe Leu Leu Pro Phe Val Ser Leu Gly Leu
                 140                 145                 150

 Met Cys Phe Gly Ala Leu Ile Gly Leu Cys Ala Cys Ile Cys Arg
                 155                 160                 165

 Ser Leu Tyr Pro Thr Ile Ala Thr Gly Ile Leu His Leu Leu Ala
                 170                 175                 180

 Gly Leu Cys Thr Leu Gly Ser Val Ser Cys Tyr Val Ala Gly Ile
                 185                 190                 195

 Glu Leu Leu His Gln Lys Leu Glu Leu Pro Asp Asn Val Ser Gly
                 200                 205                 210

 Glu Phe Gly Trp Ser Phe Cys Leu Ala Cys Val Ser Ala Pro Leu
                 215                 220                 225

 Gln Phe Met Ala Ser Ala Leu Phe Ile Trp Ala Ala His Thr Asn
                 230                 235                 240

 Arg Lys Glu Tyr Thr Leu Met Lys Ala Tyr Arg Val Ala
                 245                 250

<210> 1865
<211> 1110
<212> DNA
<213> Homo sapien

<400> 1865
 ctttccgctc ggctgttttc ctgcgcagga gccgcagggc cgtaggcagc 50

 catggcgccc agccggaatg gcatggtctt gaagccccac ttccacaagg 100

 actggcagcg gcgcgtggcc acgtggttca accagccggc ccgtaagatc 150

 cgcagacgta aggcccggca agccaaggcg cgccgcatcg ccccgcgccc 200

 cgcgtcgggt cccatccggc ccatcgtgcg ctgccccacg gttcggtacc 250

 acacgaaggt gcgcgccggc cgcggcttca gcctggagga gctcagggtg 300

 gccggcattc acaagaaggt ggcccggacc atcggcattt ctgtggatcc 350

 gaggaggcgg aacaagtcca cggagtccct gcaggccaac gtgcagcggc 400

 tgaaggagta ccgctccaaa ctcatcctct tccccaggaa gccctcggcc 450

 cccaagaagg gagacagttc tgctgaagaa ctgaaactgg ccacccagct 500

 gaccggaccg gtcatgcccg tccggaacgt ctataagaag gagaaagctc 550

 gagtcatcac tgaggaagag aagaatttca aagccttcgc tagtctccgt 600

 atggcccgtg ccaacgcccg gctcttcggc atacgggcaa aaagagccaa 650

 ggaagccgca gaacaggatg ttgaaaagaa aaaataaagc cctcctgggg 700

 acttggaatc agtcggcagt catgctgggt ctccacgtgg tgtgtttcgt 750

 gggaacaact gggcctggga tggggcttca ctgctgtgac ttcctcctgc 800

 caggggattt ggggctttct tgaaagacag tccaagccct ggataatgct 850

 ttactttctg tgttgaagca ctgttggttg tttggttagt gactgatgta 900

 aaacggtttt cttgtgggga ggttacagag gctgacttca gagtggactt 950

 gtgttttttc tttttaaaga ggcaaggttg ggctggtgct cacagctgta 1000

 atcccagcac tttgaggttg gctgggagtt caagaccagc ctggccaaca 1050

 tgtcagaact actaaaaata aagaaatcag ccatgaaaaa aaaaaaaaaa 1100

 aaaaaaaaaa 1110

<210> 1866
<211> 211
<212> PRT
<213> Homo sapien

<400> 1866
 Met Ala Pro Ser Arg Asn Gly Met Val Leu Lys Pro His Phe His
   1               5                  10                  15

 Lys Asp Trp Gln Arg Arg Val Ala Thr Trp Phe Asn Gln Pro Ala
                  20                  25                  30

 Arg Lys Ile Arg Arg Arg Lys Ala Arg Gln Ala Lys Ala Arg Arg
                  35                  40                  45

 Ile Ala Pro Arg Pro Ala Ser Gly Pro Ile Arg Pro Ile Val Arg
                  50                  55                  60

 Cys Pro Thr Val Arg Tyr His Thr Lys Val Arg Ala Gly Arg Gly
                  65                  70                  75

 Phe Ser Leu Glu Glu Leu Arg Val Ala Gly Ile His Lys Lys Val
                  80                  85                  90

 Ala Arg Thr Ile Gly Ile Ser Val Asp Pro Arg Arg Arg Asn Lys
                  95                 100                 105

 Ser Thr Glu Ser Leu Gln Ala Asn Val Gln Arg Leu Lys Glu Tyr
                 110                 115                 120

 Arg Ser Lys Leu Ile Leu Phe Pro Arg Lys Pro Ser Ala Pro Lys
                 125                 130                 135

 Lys Gly Asp Ser Ser Ala Glu Glu Leu Lys Leu Ala Thr Gln Leu
                 140                 145                 150

 Thr Gly Pro Val Met Pro Val Arg Asn Val Tyr Lys Lys Glu Lys
                 155                 160                 165

 Ala Arg Val Ile Thr Glu Glu Glu Lys Asn Phe Lys Ala Phe Ala
                 170                 175                 180

 Ser Leu Arg Met Ala Arg Ala Asn Ala Arg Leu Phe Gly Ile Arg
                 185                 190                 195

 Ala Lys Arg Ala Lys Glu Ala Ala Glu Gln Asp Val Glu Lys Lys
                 200                 205                 210

 Lys


<210> 1867
<211> 2593
<212> DNA
<213> Homo sapien

<400> 1867
 tggacttgga tccgaggcag acgaggaagc tgagaaaacc ctggcgttga 50

 ccccgtggac ctgggcgccc cgggaaggtc cagcgcttgg tccaggcagg 100

 cggggatgtg cggtgaccac cctggtcctg aaaagtccag ccccgaatct 150

 ccctccctcc tagacctgga ggcctggaac agccagccgc ccacggacgc 200

 cagagccggg aaccctgacg gcacttagct gctgacaaac aacctgctcc 250

 gtggacgcct gaaacaccag tctttggggc cagtgcctca gtttcaatcc 300

 aggtaacctt taaatgaaac ttgcctaaaa tcttaggtca tacacagaag 350

 agactccaat cgacaagaag ctggaaaaga atgatgttgt ccttaaacaa 400

 cctacagaat atcatctata acccggtaat cccgtatgtt ggcaccattc 450

 ccgatcagct ggatcctgga actttgattg tgatatgtgg gcatgttcct 500

 agtgacgcag acagattcca ggtggatctg cagaatggca gcagtgtgaa 550

 acctcgagcc gatgtggcct ttcatttcaa tcctcgtttc aaaagggccg 600

 gctgcattgt ttgcaatact ttgataaatg aaaaatgggg acgggaagag 650

 atcacctatg acacgccttt caaaagagaa aagtcttttg agatcgtgat 700

 tatggtgcta aaggacaaat tccaggtggc tgtaaatgga aaacatactc 750

 tgctctatgg ccacaggatc ggcccagaga aaatagacac tctgggcatt 800

 tatggcaaag tgaatattca ctcaattggt tttagcttca gctcggactt 850

 acaaagtacc caagcatcta gtctggaact gacagagata agtagagaaa 900

 atgttccaaa gtctggcacg ccccagcttc agactgtctc tccctcctgg 950

 gatttacagg gtcatggctc tgaaacattc tgtagtgttc tttggacacg 1000

 agttttcctg gagatcgctt tctgcaggcc tattggtctg actgtggctt 1050

 cttttcagag cctgccattc gctgcaaggt tgaacacccc catgggccct 1100

 ggacgaactg tcgtcgttaa aggagaagtg aatgcaaatg ccaaaagctt 1150

 taatgttgac ctactagcag gaaaatcaaa ggatattgct ctacacttga 1200

 acccacgcct gaatattaaa gcatttgtaa gaaattcttt tcttcaggag 1250

 tcctggggag aagaagagag aaatattacc tctttcccat ttagtcctgg 1300

 gatgtacttt gagatgataa tttactgtga tgttagagaa ttcaaggttg 1350

 cagtaaatgg cgtacacagc ctggagtaca aacacagatt taaagagctc 1400

 agcagtattg acacgctgga aattaatgga gacatccact tactggaagt 1450

 aaggagctgg tagcctacct acacagctgc tacaaaaacc aaaatacaga 1500

 atggcttctg tgatactggc cttgctgaaa cgcatctcac tgtcattcta 1550

 ttgtttatat tgttaaaatg agcttgtgca ccattagatc ctgctgggtg 1600

 ttctcagtcc ttgccatgaa gtatggtggt gtctagcact gaatggggaa 1650

 actgggggca gcaacactta tagccagtta aagccactct gccctctctc 1700

 ctactttggc tgactcttca agaatgccat tcaacaagta tttatggagt 1750

 acctactata atacagtagc taacatgtat tgagcacaga ttttttttgg 1800

 taaaactgtg aggagctagg atatatactt ggtgaaacaa accagtatgt 1850

 tccctgttct cttgagcttc gactcttctg tgctctattg ctgcgcactg 1900

 ctttttctac aggcattaca tcaactccta aggggtcctc tgggattagt 1950

 taagcagcta ttaaatcacc cgaagacact aatttacaga agacacaact 2000

 ccttccccag tgatcactgt cataaccagt gctctaccgt atcccatcac 2050

 tgaggactga tgttgactga catcatttta tcgtaataaa catgtggctc 2100

 tattagctgc aagctttacc aagtaattgg catgacatct gagcacagaa 2150

 attaaggcaa aaaaccaaag caaaacaaat acatggtgct gaaattaact 2200

 tgatgccaag cccaaggcag ctgatttctg tgtatttgaa cttagggcaa 2250

 atcagagtct acacagacgc ctacagaaag tttcaggaag aggcaagatg 2300

 cattcaattt gaaagatatt tatgggcaac aaagtaaggt caggattaga 2350

 cttcaggcat tcataaggca ggcactatca gaaagtgtac gccaactaag 2400

 ggacccacaa agcaggcaga ggtaatgcag aaatctgttt tgttcccatg 2450

 aaatcaccaa tcaaggcctc cgttcttcta aagattagtc catcatcatt 2500

 agcaactgag atcaaagcac tcttccactt tacgtgatta aaatcaaacc 2550

 tgtatcagca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2593

<210> 1868
<211> 359
<212> PRT
<213> Homo sapien

<400> 1868
 Met Leu Ser Leu Asn Asn Leu Gln Asn Ile Ile Tyr Asn Pro Val
   1               5                  10                  15

 Ile Pro Tyr Val Gly Thr Ile Pro Asp Gln Leu Asp Pro Gly Thr
                  20                  25                  30

 Leu Ile Val Ile Cys Gly His Val Pro Ser Asp Ala Asp Arg Phe
                  35                  40                  45

 Gln Val Asp Leu Gln Asn Gly Ser Ser Val Lys Pro Arg Ala Asp
                  50                  55                  60

 Val Ala Phe His Phe Asn Pro Arg Phe Lys Arg Ala Gly Cys Ile
                  65                  70                  75

 Val Cys Asn Thr Leu Ile Asn Glu Lys Trp Gly Arg Glu Glu Ile
                  80                  85                  90

 Thr Tyr Asp Thr Pro Phe Lys Arg Glu Lys Ser Phe Glu Ile Val
                  95                 100                 105

 Ile Met Val Leu Lys Asp Lys Phe Gln Val Ala Val Asn Gly Lys
                 110                 115                 120

 His Thr Leu Leu Tyr Gly His Arg Ile Gly Pro Glu Lys Ile Asp
                 125                 130                 135

 Thr Leu Gly Ile Tyr Gly Lys Val Asn Ile His Ser Ile Gly Phe
                 140                 145                 150

 Ser Phe Ser Ser Asp Leu Gln Ser Thr Gln Ala Ser Ser Leu Glu
                 155                 160                 165

 Leu Thr Glu Ile Ser Arg Glu Asn Val Pro Lys Ser Gly Thr Pro
                 170                 175                 180

 Gln Leu Gln Thr Val Ser Pro Ser Trp Asp Leu Gln Gly His Gly
                 185                 190                 195

 Ser Glu Thr Phe Cys Ser Val Leu Trp Thr Arg Val Phe Leu Glu
                 200                 205                 210

 Ile Ala Phe Cys Arg Pro Ile Gly Leu Thr Val Ala Ser Phe Gln
                 215                 220                 225

 Ser Leu Pro Phe Ala Ala Arg Leu Asn Thr Pro Met Gly Pro Gly
                 230                 235                 240

 Arg Thr Val Val Val Lys Gly Glu Val Asn Ala Asn Ala Lys Ser
                 245                 250                 255

 Phe Asn Val Asp Leu Leu Ala Gly Lys Ser Lys Asp Ile Ala Leu
                 260                 265                 270

 His Leu Asn Pro Arg Leu Asn Ile Lys Ala Phe Val Arg Asn Ser
                 275                 280                 285

 Phe Leu Gln Glu Ser Trp Gly Glu Glu Glu Arg Asn Ile Thr Ser
                 290                 295                 300

 Phe Pro Phe Ser Pro Gly Met Tyr Phe Glu Met Ile Ile Tyr Cys
                 305                 310                 315

 Asp Val Arg Glu Phe Lys Val Ala Val Asn Gly Val His Ser Leu
                 320                 325                 330

 Glu Tyr Lys His Arg Phe Lys Glu Leu Ser Ser Ile Asp Thr Leu
                 335                 340                 345

 Glu Ile Asn Gly Asp Ile His Leu Leu Glu Val Arg Ser Trp
                 350                 355

<210> 1869
<211> 2593
<212> DNA
<213> Homo sapien

<400> 1869
 tggacttgga tccgaggcag acgaggaagc tgagaaaacc ctggcgttga 50

 ccccgtggac ctgggcgccc cgggaaggtc cagcgcttgg tccaggcagg 100

 cggggatgtg cggtgaccac cctggtcctg aaaagtccag ccccgaatct 150

 ccctccctcc tagacctgga ggcctggaac agccagccgc ccacggacgc 200

 cagagccggg aaccctgacg gcacttagct gctgacaaac aacctgctcc 250

 gtggacgcct gaaacaccag tctttggggc cagtgcctca gtttcaatcc 300

 aggtaacctt taaatgaaac ttgcctaaaa tcttaggtca tacacagaag 350

 agactccaat cgacaagaag ctggaaaaga atgatgttgt ccttaaacaa 400

 cctacagaat atcatctata acccggtaat cccgtatgtt ggcaccattc 450

 ccgatcagct ggatcctgga actttgattg tgatatgtgg gcatgttcct 500

 agtgacgcag acagattcca ggtggatctg cagaatggca gcagtgtgaa 550

 acctcgagcc gatgtggcct ttcatttcaa tcctcgtttc aaaagggccg 600

 gctgcattgt ttgcaatact ttgataaatg aaaaatgggg acgggaagag 650

 atcacctatg acacgccttt caaaagagaa aagtcttttg agatcgtgat 700

 tatggtgcta aaggacaaat tccaggtggc tgtaaatgga aaacatactc 750

 tgctctatgg ccacaggatc ggcccagaga aaatagacac tctgggcatt 800

 tatggcaaag tgaatattca ctcaattggt tttagcttca gctcggactt 850

 acaaagtacc caagcatcta gtctggaact gacagagata agtagagaaa 900

 atgttccaaa gtctggcacg ccccagcttc agactgtctc tccctcctgg 950

 gatttacagg gtcatggctc tgaaacattc tgtagtgttc tttggacacg 1000

 agttttcctg gagatcgctt tctgcaggcc tattggtctg actgtggctt 1050

 cttttcagag cctgccattc gctgcaaggt tgaacacccc catgggccct 1100

 ggacgaactg tcgtcgttaa aggagaagtg aatgcaaatg ccaaaagctt 1150

 taatgttgac ctactagcag gaaaatcaaa ggatattgct ctacacttga 1200

 acccacgcct gaatattaaa gcatttgtaa gaaattcttt tcttcaggag 1250

 tcctggggag aagaagagag aaatattacc tctttcccat ttagtcctgg 1300

 gatgtacttt gagatgataa tttactgtga tgttagagaa ttcaaggttg 1350

 cagtaaatgg cgtacacagc ctggagtaca aacacagatt taaagagctc 1400

 agcagtattg acacgctgga aattaatgga gacatccact tactggaagt 1450

 aaggagctgg tagcctacct acacagctgc tacaaaaacc aaaatacaga 1500

 atggcttctg tgatactggc cttgctgaaa cgcatctcac tgtcattcta 1550

 ttgtttatat tgttaaaatg agcttgtgca ccattagatc ctgctgggtg 1600

 ttctcagtcc ttgccatgaa gtatggtggt gtctagcact gaatggggaa 1650

 actgggggca gcaacactta tagccagtta aagccactct gccctctctc 1700

 ctactttggc tgactcttca agaatgccat tcaacaagta tttatggagt 1750

 acctactata atacagtagc taacatgtat tgagcacaga ttttttttgg 1800

 taaaactgtg aggagctagg atatatactt ggtgaaacaa accagtatgt 1850

 tccctgttct cttgagcttc gactcttctg tgctctattg ctgcgcactg 1900

 ctttttctac aggcattaca tcaactccta aggggtcctc tgggattagt 1950

 taagcagcta ttaaatcacc cgaagacact aatttacaga agacacaact 2000

 ccttccccag tgatcactgt cataaccagt gctctaccgt atcccatcac 2050

 tgaggactga tgttgactga catcatttta tcgtaataaa catgtggctc 2100

 tattagctgc aagctttacc aagtaattgg catgacatct gagcacagaa 2150

 attaaggcaa aaaaccaaag caaaacaaat acatggtgct gaaattaact 2200

 tgatgccaag cccaaggcag ctgatttctg tgtatttgaa cttagggcaa 2250

 atcagagtct acacagacgc ctacagaaag tttcaggaag aggcaagatg 2300

 cattcaattt gaaagatatt tatgggcaac aaagtaaggt caggattaga 2350

 cttcaggcat tcataaggca ggcactatca gaaagtgtac gccaactaag 2400

 ggacccacaa agcaggcaga ggtaatgcag aaatctgttt tgttcccatg 2450

 aaatcaccaa tcaaggcctc cgttcttcta aagattagtc catcatcatt 2500

 agcaactgag atcaaagcac tcttccactt tacgtgatta aaatcaaacc 2550

 tgtatcagca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2593

<210> 1870
<211> 359
<212> PRT
<213> Homo sapien

<400> 1870
 Met Leu Ser Leu Asn Asn Leu Gln Asn Ile Ile Tyr Asn Pro Val
   1               5                  10                  15

 Ile Pro Tyr Val Gly Thr Ile Pro Asp Gln Leu Asp Pro Gly Thr
                  20                  25                  30

 Leu Ile Val Ile Cys Gly His Val Pro Ser Asp Ala Asp Arg Phe
                  35                  40                  45

 Gln Val Asp Leu Gln Asn Gly Ser Ser Val Lys Pro Arg Ala Asp
                  50                  55                  60

 Val Ala Phe His Phe Asn Pro Arg Phe Lys Arg Ala Gly Cys Ile
                  65                  70                  75

 Val Cys Asn Thr Leu Ile Asn Glu Lys Trp Gly Arg Glu Glu Ile
                  80                  85                  90

 Thr Tyr Asp Thr Pro Phe Lys Arg Glu Lys Ser Phe Glu Ile Val
                  95                 100                 105

 Ile Met Val Leu Lys Asp Lys Phe Gln Val Ala Val Asn Gly Lys
                 110                 115                 120

 His Thr Leu Leu Tyr Gly His Arg Ile Gly Pro Glu Lys Ile Asp
                 125                 130                 135

 Thr Leu Gly Ile Tyr Gly Lys Val Asn Ile His Ser Ile Gly Phe
                 140                 145                 150

 Ser Phe Ser Ser Asp Leu Gln Ser Thr Gln Ala Ser Ser Leu Glu
                 155                 160                 165

 Leu Thr Glu Ile Ser Arg Glu Asn Val Pro Lys Ser Gly Thr Pro
                 170                 175                 180

 Gln Leu Gln Thr Val Ser Pro Ser Trp Asp Leu Gln Gly His Gly
                 185                 190                 195

 Ser Glu Thr Phe Cys Ser Val Leu Trp Thr Arg Val Phe Leu Glu
                 200                 205                 210

 Ile Ala Phe Cys Arg Pro Ile Gly Leu Thr Val Ala Ser Phe Gln
                 215                 220                 225

 Ser Leu Pro Phe Ala Ala Arg Leu Asn Thr Pro Met Gly Pro Gly
                 230                 235                 240

 Arg Thr Val Val Val Lys Gly Glu Val Asn Ala Asn Ala Lys Ser
                 245                 250                 255

 Phe Asn Val Asp Leu Leu Ala Gly Lys Ser Lys Asp Ile Ala Leu
                 260                 265                 270

 His Leu Asn Pro Arg Leu Asn Ile Lys Ala Phe Val Arg Asn Ser
                 275                 280                 285

 Phe Leu Gln Glu Ser Trp Gly Glu Glu Glu Arg Asn Ile Thr Ser
                 290                 295                 300

 Phe Pro Phe Ser Pro Gly Met Tyr Phe Glu Met Ile Ile Tyr Cys
                 305                 310                 315

 Asp Val Arg Glu Phe Lys Val Ala Val Asn Gly Val His Ser Leu
                 320                 325                 330

 Glu Tyr Lys His Arg Phe Lys Glu Leu Ser Ser Ile Asp Thr Leu
                 335                 340                 345

 Glu Ile Asn Gly Asp Ile His Leu Leu Glu Val Arg Ser Trp
                 350                 355

<210> 1871
<211> 1656
<212> DNA
<213> Homo sapien

<400> 1871
 ggcgggagcg cggcggcccg gctcccgcag ggccgcgccg aggcaggcga 50

 gcccccgcgg cgcccaggcg cgggcccggg cccccgccgc cgccgccgcc 100

 gccgggcgcg gcatttttat tcaggcgacg cttaagggag cccggccgcg 150

 cccggtgcat tgtgggagcg gcccgcggcc cgttttcggg aggaggcgga 200

 gggcgcaaag cgagccggtg gatccataaa gaacccagcc aacccgcaga 250

 gggaggggag gggctgagct gtgaggagag cggggcccaa gaaccatgtc 300

 tacgcgggag tcctttaacc cggaaagtta cgaattggac aaaagcttcc 350

 ggctaaccag attcactgaa ctgaagggca caggctgcaa agtgccccaa 400

 gatgtcctgc aaaaattgct ggaatcttta caggagaacc acttccaaga 450

 agatgagcag tttctgggag ccgttatgcc aaggcttggc attggaatgg 500

 atacttgtgt cattcctttg aggcacggtg ggctttcctt ggttcaaacc 550

 acagattaca tttacccgat cgtagacgac ccttacatga tgggcaggat 600

 agcgtgtgcc aatgtcctca gtgacctcta tgcaatgggg gtcacggaat 650

 gtgacaatat gctgatgctc cttggagtca gtaataaaat gaccgacagg 700

 gaaagggata aagtgatgcc tctgattatc caaggtttta aagacgcagc 750

 tgaggaagca ggaacatctg taacaggcgg ccaaacagta ctaaacccct 800

 ggattgtcct gggaggagtg gctaccactg tctgccaacc caatgaattt 850

 atcatgccag acaatgcagt gccaggggac gtgctggtgc tgacaaaacc 900

 cctggggaca caggtggcag tggctgtgca ccagtggctg gatatccctg 950

 agaaatggaa taagattaaa ctagtggtca cccaagaaga tgtagagctg 1000

 gcctaccagg aggcgatgat gaacatggcg aggctcaaca ggacagctgc 1050

 aggactcatg cacacgttca atgcccacgc cgccactgac atcacgggct 1100

 tcgggatttt gggccatgcg cagaacctgg ccaagcagca gaggaacgag 1150

 gtgtcgtttg taattcacaa cctcccggtg ctggccaaga tggctgcggt 1200

 gagcaaggcc tgcggaaaca tgttcggcct catgcacggg acctgcccgg 1250

 agacttcagg cggccttctg atctgtttac cacgtgagca agcagctcgg 1300

 ttctgtgcag agataaagtc ccccaaatat ggtgaaggcc accaagcatg 1350

 gattattggg attgtagaga agggcaaccg cacagccaga atcatagaca 1400

 aaccccggat catcgaggtc gcaccacaag tggccactca aaatgtgaat 1450

 cccacacccg gggccacctc ttaatctaga cagaaatagc tgtttggttt 1500

 tgtttttaaa tagatctatt tcccttatca cttcaattaa agactataaa 1550

 caacaaaaat ctcattgtgt ctacacatcg gggtgacctt aggtcggttt 1600

 gtaagtggat acaattaata aaataaaatc cattgccttt ttaaaaaaaa 1650

 aaaaaa 1656

<210> 1872
<211> 383
<212> PRT
<213> Homo sapien

<400> 1872
 Met Ser Thr Arg Glu Ser Phe Asn Pro Glu Ser Tyr Glu Leu Asp
   1               5                  10                  15

 Lys Ser Phe Arg Leu Thr Arg Phe Thr Glu Leu Lys Gly Thr Gly
                  20                  25                  30

 Cys Lys Val Pro Gln Asp Val Leu Gln Lys Leu Leu Glu Ser Leu
                  35                  40                  45

 Gln Glu Asn His Phe Gln Glu Asp Glu Gln Phe Leu Gly Ala Val
                  50                  55                  60

 Met Pro Arg Leu Gly Ile Gly Met Asp Thr Cys Val Ile Pro Leu
                  65                  70                  75

 Arg His Gly Gly Leu Ser Leu Val Gln Thr Thr Asp Tyr Ile Tyr
                  80                  85                  90

 Pro Ile Val Asp Asp Pro Tyr Met Met Gly Arg Ile Ala Cys Ala
                  95                 100                 105

 Asn Val Leu Ser Asp Leu Tyr Ala Met Gly Val Thr Glu Cys Asp
                 110                 115                 120

 Asn Met Leu Met Leu Leu Gly Val Ser Asn Lys Met Thr Asp Arg
                 125                 130                 135

 Glu Arg Asp Lys Val Met Pro Leu Ile Ile Gln Gly Phe Lys Asp
                 140                 145                 150

 Ala Ala Glu Glu Ala Gly Thr Ser Val Thr Gly Gly Gln Thr Val
                 155                 160                 165

 Leu Asn Pro Trp Ile Val Leu Gly Gly Val Ala Thr Thr Val Cys
                 170                 175                 180

 Gln Pro Asn Glu Phe Ile Met Pro Asp Asn Ala Val Pro Gly Asp
                 185                 190                 195

 Val Leu Val Leu Thr Lys Pro Leu Gly Thr Gln Val Ala Val Ala
                 200                 205                 210

 Val His Gln Trp Leu Asp Ile Pro Glu Lys Trp Asn Lys Ile Lys
                 215                 220                 225

 Leu Val Val Thr Gln Glu Asp Val Glu Leu Ala Tyr Gln Glu Ala
                 230                 235                 240

 Met Met Asn Met Ala Arg Leu Asn Arg Thr Ala Ala Gly Leu Met
                 245                 250                 255

 His Thr Phe Asn Thr His Ala Ala Thr Asp Ile Thr Gly Phe Gly
                 260                 265                 270

 Ile Leu Gly His Ala Gln Asn Leu Ala Lys Gln Gln Arg Asn Glu
                 275                 280                 285

 Val Ser Phe Val Ile His Asn Leu Pro Val Leu Ala Lys Met Ala
                 290                 295                 300

 Ala Val Ser Lys Ala Cys Gly Asn Met Phe Gly Leu Met His Gly
                 305                 310                 315

 Thr Cys Pro Glu Thr Ser Gly Gly Leu Leu Ile Cys Leu Pro Arg
                 320                 325                 330

 Glu Gln Ala Ala Arg Phe Cys Ala Glu Ile Lys Ser Pro Lys Tyr
                 335                 340                 345

 Gly Glu Gly His Gln Ala Trp Ile Ile Gly Ile Val Glu Lys Gly
                 350                 355                 360

 Asn Arg Thr Ala Arg Ile Ile Asp Lys Pro Arg Ile Ile Glu Val
                 365                 370                 375

 Ala His Lys Trp Pro Leu Lys Thr
                 380

<210> 1873
<211> 5759
<212> DNA
<213> Homo sapien

<400> 1873
 ataccctgtg gtgctagtgt aaaatcaaat ataatctacc tctttagctt 50

 ttctgttatg taattggaat gaaaaaatag tgcttttttt tttttttcat 100

 ttttgagatt gagttaccat ggagggaaag aacatgtgtt ttaccagtgg 150

 aacgcattct ttgtgttatc tcttcgattt ttaacatttt atgtttccag 200

 tttataaact ttgcctccag tttgatgaag aaaatttagc tattagaaag 250

 tatttaaaat ctcaaaagta tgacatttta aaatgttagc aggtttaaag 300

 ataacttagt ttttcaactc ttaacccaaa attatacttg tatactataa 350

 tttgtgttga attacttggt attatttatc atcctagtaa gatctatttt 400

 atataatttg attcactttt tatattgaat tatgttaatt gtttttgtaa 450

 tacacctttc atatttcttc aaagaaaact agtgttgggt tattgctaat 500

 tttgcttcgt ggtttggtta tttacatata aaaattatat tgttttaaaa 550

 attgcaaagt gatcatttat tgacacatca gcaagaatta atgttgaaat 600

 gcaagttttt tcccctatcc ttaactaagt gtgtagatat ctttgttttg 650

 tttctttaat agatagcaaa caataaagat gcattgagga agacatggaa 700

 ccctaagttt acattgagaa gtcactttga tggcatccga gcccttgctt 750

 tccatcccat tgagcctgtt ttgataacag catcagagga tcacacatta 800

 aaaatgtgga atttacagaa aacagcccca gccaaaaagt gagaatattc 850

 tactttaaca ttatttgaat attttaagta acattttcag cagaaaacta 900

 catattttat gatttctgtt aaatttccca aacatttctt ctagttcttt 950

 cttccatgtc atgtaattta ttgtgttttt ccatttatac aacctaatgc 1000

 taggttagaa aactgatgct taggaagata tggtattatc ttttggtttc 1050

 accagggttt gtgaatactg attacagtct ttatacataa cagtattttt 1100

 aaatggctgc tatatttggg gagccccttg tctatactga aggtttggac 1150

 tgttcttgta aacaggtata tgcatcttta aaataatcaa atgtccacct 1200

 ccaccttgcc ccattgttta ctagatttag acttatgaga tggagcagag 1250

 aaaagcctca ctgggatggg tggagggtct tggtcttgtc ttttggcctt 1300

 gagactttag gtactttcca tacccaccaa tatgtctaga ctcagaggct 1350

 aacatgactg ctagtgctca ccttggccct ttagttcctg tctaagcatg 1400

 gatagacatg agttagtata aaccctttaa aagtcacaaa gctaaatctg 1450

 gttctacttg cttgggtcct tatcggagct ccactccttt gggtcacatg 1500

 tcaaaaaaaa aaaaaaaaag gcgccgtccg ctgcgctggg ggctcggtct 1550

 atgacgagca gcggggtctg ccatgggtcg ggggctgctc aggggcctgt 1600

 ggccgctgca catcgtcctg tggacgcgta tcgccagcac gatcccaccg 1650

 cacgttcaga agtcggttaa taacgacatg atagtcactg acaacaacgg 1700

 tgcagtcaag tttccacaac tgtgtaaatt ttgtgatgtg agattttcca 1750

 cctgtgacaa ccagaaatcc tgcatgagca actgcagcat cacctccatc 1800

 tgtgagaagc cacaggaagt ctgtgtggct gtatggagaa agaatgacga 1850

 gaacataaca ctagagacag tttgccatga ccccaagctc ccctaccatg 1900

 actttattct ggaagatgct gcttctccaa agtgcattat gaaggaaaaa 1950

 aaaaagcctg gtgagacttt cttcatgtgt tcctgtagct ctgatgagtg 2000

 caatgacaac atcatcttct cagaagaata taacaccagc aatcctgact 2050

 tgttgctagt catatttcaa gtgacaggca tcagcctcct gccaccactg 2100

 ggagttgcca tatctgtcat catcatcttc tactgctacc gcgttaaccg 2150

 gcagcagaag ctgagttcaa cctgggaaac cggcaagacg cggaagctca 2200

 tggagttcag cgagcactgt gccatcatcc tggaagatga ccgctctgac 2250

 atcagctcca cgtgtgccaa caacatcaac cacaacacag agctgctgcc 2300

 cattgagctg gacaccctgg tggggaaagg tcgctttgct gaggtctata 2350

 aggccaagct gaagcagaac acttcagagc agtttgagac agtggcagtc 2400

 aagatctttc cctatgagga gtatgcctct tggaagacag agaaggacat 2450

 cttctcagac atcaatctga agcatgagaa catactccag ttcctgacgg 2500

 ctgaggagcg gaagacggag ttggggaaac aatactggct gatcaccgcc 2550

 ttccacgcca agggcaacct acaggagtac ctgacgcggc atgtcatcag 2600

 ctgggaggac ctgcgcaagc tgggcagctc cctcgcccgg gggattgctc 2650

 acctccacag tgatcacact ccatgtggga ggcccaagat gcccatcgtg 2700

 cacagggacc tcaacagctc caatatcctc gtgaagaacg acctaacctg 2750

 ctgcctgtgt gactttgggc tttccctgcg tctggaccct actctgtctg 2800

 tggatgacct ggctaacagt gggcaggtgg gaactgcaag atacatggct 2850

 ccagaagtcc tagaatccag gatgaatttg gagaatgctg agtccttcaa 2900

 gcagaccgat gtctactcca tggctctggt gctctgggaa atgacatctc 2950

 gctgtaatgc agtgggagaa gtaaaagatt atgagcctcc atttggttcc 3000

 aaggtgcggg agcacccctg tgtcgaaagc atgaaggaca acgtgttgag 3050

 agatcgaggg cgaccagaaa ttcccagctt ctggctcaac caccagggca 3100

 tccagatggt gtgtgagacg ttgactgagt gctgggacca cgacccagag 3150

 gcccgtctca cagcccagtg tgtggcagaa cgcttcagtg agctggagca 3200

 tctggacagg ctctcgggga ggagctgctc ggaggagaag attcctgaag 3250

 acggctccct aaacactacc aaatagctct tctggggcag gctgggccat 3300

 gtccaaagag gctgcccctc tcaccaaaga acagaggcag caggaagctg 3350

 cccctgaact gatgcttcct ggaaaaccaa gggggtcact cccctccctg 3400

 taagctgtgg ggataagcag aaacaacagc agcagggagt gggtgacata 3450

 gagcattcta tgccttttac attgtcatag gataagctgt gttagcactt 3500

 cctcaggaaa tgagattgat tttacaatag ccaataacat ttgcacttta 3550

 ttaatgcctg tatataaata tgaatagcta tgttttatat atatatatat 3600

 atatctatat atgtctatag ctctatatat atagccatac cttgaaaaga 3650

 gacaaggaaa aacatcaaat attcccagga aattggtttt attggagaac 3700

 tccagaacca agcagagaag gaagggaccc atgacagcat tagcatttga 3750

 caatcacaca tgcagtggtt ctctgactgt aaaacagtga actttgcatg 3800

 aggaaagagg ctccatgtct cacagccagc tatgaccaca ttgcacttgc 3850

 ttttgcaaaa taatcattcc ctgcctagca cttctcttct ggccatggaa 3900

 ctaagtacag tggcactgtt tgaggaccag tgttcccggg gttcctgtgt 3950

 gcccttattt ctcctggact tttcatttaa gctccaagcc ccaaatctgg 4000

 ggggctagtt tagaaactct ccctcaacct agtttagaaa ctctacccca 4050

 tctttaatac cttgaatgtt ttgaacccca ctttttacct tcatgggttg 4100

 cagaaaaatc agaacagatg tccccatcca tgcgattgcc ccaccatcta 4150

 ctaatgaaaa attgttcttt ttttcatctt tcccctgcac ttatgttact 4200

 attctctgct cccagccttc atccttttct aaaaaggagc aaattctcac 4250

 tctaggcttt atcgtgttta ctttttcatt acacttgact tgattttcta 4300

 gttttctata caaacaccaa tgggttccat ctttctgggc tcctgattgc 4350

 tcaagcacag tttggcctga tgaagaggat ttcaactaca caatactatc 4400

 attgtcagga ctatgacctc aggcactcta aacatatgtt ttgtttggtc 4450

 agcacagcgt ttcaaaaagt gaagccactt tataaatatt tggagatttt 4500

 gcaggaaaat ctggatcccc aggtaaggat agcagatggt tttcagttat 4550

 ctccagtcca cgttcacaaa atgtgaaggt gtggagacac ttacaaagct 4600

 gcctcacttc tcactgtaaa cattagctct ttccactgcc tacctggacc 4650

 ccagtctagg aattaaatct gcacctaacc aaggtccctt gtaagaaatg 4700

 tccattcaag cagtcattct ctgggtatat aatatgattt tgactacctt 4750

 atctggtgtt aagatttgaa gttggccttt tattggacta aaggggaact 4800

 cctttaaggg tctcagttag cccaagtttc ttttgcttat atgttaatag 4850

 ttttaccctc tgcattggag agaggagtgc tttactccaa gaagctttcc 4900

 tcatggttac cgttctctcc atcatgccag ccttctcaac ctttgcagaa 4950

 attactagag aggatttgaa tgtgggacac aaaggtccca tttgcagtta 5000

 gaaaatttgt gtccacaagg acaagaacaa agtatgagct ttaaaactcc 5050

 ataggaaact tgttaatcaa caaagaagtg ttaatgctgc aagtaatctc 5100

 ttttttaaaa ctttttgaag ctacttattt tcagccaaat aggaatatta 5150

 gagagggact ggtagtgaga atatcagctc tgtttggatg gtggaaggtc 5200

 tcattttatt gagattttta agatacatgc aaaggtttgg aaatagaacc 5250

 tctaggcacc ctcctcagtg tgggtgggct gagagttaaa gacagtgtgg 5300

 ctgcagtagc atagaggcgc ctagaaattc cacttgcacc gtagggcatg 5350

 ctgataccat cccaatagct gttgcccatt gacctctagt ggtgagtttc 5400

 tagaatactg gtccattcat gagatattca agattcaaga gtattctcac 5450

 ttctgggtta tcagcataaa ctggaatgta gtgtcagagg atactgtggc 5500

 ttgttttgtt tatgtttttt tttcttattc aagaaaaaag accaaggaat 5550

 aacattctgt agttcctaaa aatactgact tttttcacta ctatacataa 5600

 agggaaagtt ttattctttt atggaacact tcagctgtac tcatgtatta 5650

 aaataggaat gtgaatgcta tatactcttt ttatatcaaa agtctcaagc 5700

 acttattttt attctatgca ttgtttgtct tttacataaa taaaatgttt 5750

 attagattg 5759

<210> 1874
<211> 567
<212> PRT
<213> Homo sapien

<400> 1874
 Met Gly Arg Gly Leu Leu Arg Gly Leu Trp Pro Leu His Ile Val
   1               5                  10                  15

 Leu Trp Thr Arg Ile Ala Ser Thr Ile Pro Pro His Val Gln Lys
                  20                  25                  30

 Ser Val Asn Asn Asp Met Ile Val Thr Asp Asn Asn Gly Ala Val
                  35                  40                  45

 Lys Phe Pro Gln Leu Cys Lys Phe Cys Asp Val Arg Phe Ser Thr
                  50                  55                  60

 Cys Asp Asn Gln Lys Ser Cys Met Ser Asn Cys Ser Ile Thr Ser
                  65                  70                  75

 Ile Cys Glu Lys Pro Gln Glu Val Cys Val Ala Val Trp Arg Lys
                  80                  85                  90

 Asn Asp Glu Asn Ile Thr Leu Glu Thr Val Cys His Asp Pro Lys
                  95                 100                 105

 Leu Pro Tyr His Asp Phe Ile Leu Glu Asp Ala Ala Ser Pro Lys
                 110                 115                 120

 Cys Ile Met Lys Glu Lys Lys Lys Pro Gly Glu Thr Phe Phe Met
                 125                 130                 135

 Cys Ser Cys Ser Ser Asp Glu Cys Asn Asp Asn Ile Ile Phe Ser
                 140                 145                 150

 Glu Glu Tyr Asn Thr Ser Asn Pro Asp Leu Leu Leu Val Ile Phe
                 155                 160                 165

 Gln Val Thr Gly Ile Ser Leu Leu Pro Pro Leu Gly Val Ala Ile
                 170                 175                 180

 Ser Val Ile Ile Ile Phe Tyr Cys Tyr Arg Val Asn Arg Gln Gln
                 185                 190                 195

 Lys Leu Ser Ser Thr Trp Glu Thr Gly Lys Thr Arg Lys Leu Met
                 200                 205                 210

 Glu Phe Ser Glu His Cys Ala Ile Ile Leu Glu Asp Asp Arg Ser
                 215                 220                 225

 Asp Ile Ser Ser Thr Cys Ala Asn Asn Ile Asn His Asn Thr Glu
                 230                 235                 240

 Leu Leu Pro Ile Glu Leu Asp Thr Leu Val Gly Lys Gly Arg Phe
                 245                 250                 255

 Ala Glu Val Tyr Lys Ala Lys Leu Lys Gln Asn Thr Ser Glu Gln
                 260                 265                 270

 Phe Glu Thr Val Ala Val Lys Ile Phe Pro Tyr Glu Glu Tyr Ala
                 275                 280                 285

 Ser Trp Lys Thr Glu Lys Asp Ile Phe Ser Asp Ile Asn Leu Lys
                 290                 295                 300

 His Glu Asn Ile Leu Gln Phe Leu Thr Ala Glu Glu Arg Lys Thr
                 305                 310                 315

 Glu Leu Gly Lys Gln Tyr Trp Leu Ile Thr Ala Phe His Ala Lys
                 320                 325                 330

 Gly Asn Leu Gln Glu Tyr Leu Thr Arg His Val Ile Ser Trp Glu
                 335                 340                 345

 Asp Leu Arg Lys Leu Gly Ser Ser Leu Ala Arg Gly Ile Ala His
                 350                 355                 360

 Leu His Ser Asp His Thr Pro Cys Gly Arg Pro Lys Met Pro Ile
                 365                 370                 375

 Val His Arg Asp Leu Asn Ser Ser Asn Ile Leu Val Lys Asn Asp
                 380                 385                 390

 Leu Thr Cys Cys Leu Cys Asp Phe Gly Leu Ser Leu Arg Leu Asp
                 395                 400                 405

 Pro Thr Leu Ser Val Asp Asp Leu Ala Asn Ser Gly Gln Val Gly
                 410                 415                 420

 Thr Ala Arg Tyr Met Ala Pro Glu Val Leu Glu Ser Arg Met Asn
                 425                 430                 435

 Leu Glu Asn Ala Glu Ser Phe Lys Gln Thr Asp Val Tyr Ser Met
                 440                 445                 450

 Ala Leu Val Leu Trp Glu Met Thr Ser Arg Cys Asn Ala Val Gly
                 455                 460                 465

 Glu Val Lys Asp Tyr Glu Pro Pro Phe Gly Ser Lys Val Arg Glu
                 470                 475                 480

 His Pro Cys Val Glu Ser Met Lys Asp Asn Val Leu Arg Asp Arg
                 485                 490                 495

 Gly Arg Pro Glu Ile Pro Ser Phe Trp Leu Asn His Gln Gly Ile
                 500                 505                 510

 Gln Met Val Cys Glu Thr Leu Thr Glu Cys Trp Asp His Asp Pro
                 515                 520                 525

 Glu Ala Arg Leu Thr Ala Gln Cys Val Ala Glu Arg Phe Ser Glu
                 530                 535                 540

 Leu Glu His Leu Asp Arg Leu Ser Gly Arg Ser Cys Ser Glu Glu
                 545                 550                 555

 Lys Ile Pro Glu Asp Gly Ser Leu Asn Thr Thr Lys
                 560                 565

<210> 1875
<211> 914
<212> DNA
<213> Homo sapien

<400> 1875
 ccagccaacg agcggaaaat ggcagacaat ttttcgctcc atgatgcgtt 50

 atctgggtct ggaaacccaa accctcaagg atggcctggc gcatggggga 100

 accagcctgc tggggcaggg ggctacccag gggcttccta tcctggggcc 150

 taccccgggc aggcaccccc aggggcttat cctggacagg cacctccagg 200

 cgcctaccat ggagcacctg gagcttatcc cggagcacct gcacctggag 250

 tctacccagg gccacccagc ggccctgggg cctacccatc ttctggacag 300

 ccaagtgccc ccggagccta ccctgccact ggcccctatg gcgcccctgc 350

 tgggccactg attgtgcctt ataacctgcc tttgcctggg ggagtggtgc 400

 ctcgcatgct gataacaatt ctgggcacgg tgaagcccaa tgcaaacaga 450

 attgctttag atttccaaag agggaatgat gttgccttcc actttaaccc 500

 acgcttcaat gagaacaaca ggagagtcat tgtttgcaat acaaagctgg 550

 ataataactg gggaagggaa gaaagacagt cggttttccc atttgaaagt 600

 gggaaaccat tcaaaataca agtactggtt gaacctgacc acttcaaggt 650

 tgcagtgaat gatgctcact tgttgcagta caatcatcgg gttaaaaaac 700

 tcaatgaaat cagcaaactg ggaatttctg gtgacataga cctcaccagt 750

 gcttcatata ccatgatata atctgaaagg ggcagattaa aaaaaaaaaa 800

 aaagaatcta aaccttacat gtgtaaaggt ttcatgttca ctgtgagtga 850

 aaatttttac attcatcaat atccctcttg taagtcatct acttaataaa 900

 tattacagtg aaag 914

<210> 1876
<211> 250
<212> PRT
<213> Homo sapien

<400> 1876
 Met Ala Asp Asn Phe Ser Leu His Asp Ala Leu Ser Gly Ser Gly
   1               5                  10                  15

 Asn Pro Asn Pro Gln Gly Trp Pro Gly Ala Trp Gly Asn Gln Pro
                  20                  25                  30

 Ala Gly Ala Gly Gly Tyr Pro Gly Ala Ser Tyr Pro Gly Ala Tyr
                  35                  40                  45

 Pro Gly Gln Ala Pro Pro Gly Ala Tyr Pro Gly Gln Ala Pro Pro
                  50                  55                  60

 Gly Ala Tyr His Gly Ala Pro Gly Ala Tyr Pro Gly Ala Pro Ala
                  65                  70                  75

 Pro Gly Val Tyr Pro Gly Pro Pro Ser Gly Pro Gly Ala Tyr Pro
                  80                  85                  90

 Ser Ser Gly Gln Pro Ser Ala Pro Gly Ala Tyr Pro Ala Thr Gly
                  95                 100                 105

 Pro Tyr Gly Ala Pro Ala Gly Pro Leu Ile Val Pro Tyr Asn Leu
                 110                 115                 120

 Pro Leu Pro Gly Gly Val Val Pro Arg Met Leu Ile Thr Ile Leu
                 125                 130                 135

 Gly Thr Val Lys Pro Asn Ala Asn Arg Ile Ala Leu Asp Phe Gln
                 140                 145                 150

 Arg Gly Asn Asp Val Ala Phe His Phe Asn Pro Arg Phe Asn Glu
                 155                 160                 165

 Asn Asn Arg Arg Val Ile Val Cys Asn Thr Lys Leu Asp Asn Asn
                 170                 175                 180

 Trp Gly Arg Glu Glu Arg Gln Ser Val Phe Pro Phe Glu Ser Gly
                 185                 190                 195

 Lys Pro Phe Lys Ile Gln Val Leu Val Glu Pro Asp His Phe Lys
                 200                 205                 210

 Val Ala Val Asn Asp Ala His Leu Leu Gln Tyr Asn His Arg Val
                 215                 220                 225

 Lys Lys Leu Asn Glu Ile Ser Lys Leu Gly Ile Ser Gly Asp Ile
                 230                 235                 240

 Asp Leu Thr Ser Ala Ser Tyr Thr Met Ile
                 245                 250

<210> 1877
<211> 2709
<212> DNA
<213> Homo sapien

<400> 1877
 gggaatagca gaataggagc aagccagcac tagtcagcta actaagtgac 50

 tcaaccaagg ccttttttcc ttgttatctt tgcagatact tcattttctt 100

 agcgtttctg gagattacaa catcctgcgg ttccgtttct gggaacttta 150

 ctgatttatc tcccccctca cacaaataag cattgattcc tgcatttctg 200

 aagatctcaa gatctggact actgttgaaa aaatttccag tgaggctcac 250

 ttatgtctgt aaagatggga aaaaaataca agaacattgt tctactaaaa 300

 ggattagagg tcatcaatga ttatcatttt agaatggtta agtccttact 350

 gagcaacgat ttaaaactta atttaaaaat gagagaagag tatgacaaaa 400

 ttcagattgc tgacttgatg gaagaaaagt tccgaggtga tgctggtttg 450

 ggcaaactaa taaaaatttt cgaagatata ccaacgcttg aagacctggc 500

 tgaaactctt aaaaaagaaa agttaaaagt aaaaggacca gccctatcaa 550

 gaaagaggaa gaaggaagtg catgctactt cacctgcacc ctccacaagc 600

 agcactgtca aaactgaagg agcagaggca actcctggag ctcagaaaag 650

 aaaaaaatca accaaagaaa aggctggacc caaagggagt aaggtgtccg 700

 aggaacagac tcagcctccc tctcctgcag gagccggcat gtccacagcc 750

 atgggccgtt ccccatctcc caagacctca ttgtcagctc cacccaacag 800

 ttcttcaact gagaacccga aaacagtggc caaatgtcag gtaactccca 850

 gaagaaatgt tctccaaaaa cgcccagtga tagtgaaggt actgagtaca 900

 acaaagccat ttgaatatga gaccccagaa atggagaaaa aaataatgtt 950

 tcatgctaca gtggctacac agacacagtt cttccatgtg aaggttttaa 1000

 acaccagctt gaaggagaaa ttcaatggaa agaaaatcat catcatatca 1050

 gattatttgg aatatgatag tctcctagag gtcaatgaag aatctactgt 1100

 atctgaagct ggtcctaacc aaacgtttga ggttccaaat aaaatcatca 1150

 acagagcaaa ggaaactctg aagattgata ttcttcacaa acaagcttca 1200

 ggaaatattg tatatggggt atttatgcta cataagaaaa cagtaaatca 1250

 gaagaccaca atctacgaaa ttcaggatga tagaggaaaa atggatgtag 1300

 tggggacagg acaatgtcac aatatcccct gtgaagaagg agataagctc 1350

 cagcttttct gctttcgact tagaaaaaag aaccagatgt caaaactgat 1400

 ttcagaaatg catagtttta tccagataaa gaaaaaaaca aacccgagaa 1450

 acaatgaccc caagagcatg aagctacccc aggaacagcg tcagcttcca 1500

 tatccttcag aggccagcac aaccttccct gagagccatc ttcggactcc 1550

 tcagatgcca ccaacaactc catccagcag tttcttcacc aagaaaagtg 1600

 aagacacaat ctccaaaatg aatgacttca tgaggatgca gatactgaag 1650

 gaagggagtc attttccagg accgttcatg accagcatag gcccagctga 1700

 gagccatccc cacactcctc agatgcctcc atcaacacca agcagcagtt 1750

 tcttaaccac gttgaaacca agactgaaga ctgaacctga agaagtttcc 1800

 atagaagaca gtgcccagag tgacctcaaa gaagtgatgg tgctgaacgc 1850

 aacagaatca tttgtatatg agcccaaaga gcagaagaaa atgtttcatg 1900

 ccacagtggc aactgagaat gaagtcttcc gagtgaaggt ttttaatatt 1950

 gacctaaagg agaagttcac cccaaagaag atcattgcca tagcaaatta 2000

 tgtttgccgc aatgggttcc tggaggtata tcctttcaca cttgtggctg 2050

 atgtgaatgc tgaccgaaac atggagatcc caaaaggatt gattagaagt 2100

 gccagcgtaa ctcctaaaat caatcagctt tgctcacaaa ctaaaggaag 2150

 ttttgtgaat ggggtgtttg aggtacataa gaaaaatgta aggggtgaat 2200

 tcacttatta tgaaatacaa gataatacag ggaagatgga agtggtggtg 2250

 catggacgac tgaacacaat caactgtgag gaaggagata aactgaaact 2300

 caccagcttt gaattggcac cgaaaagtgg gaataccggg gagttgagat 2350

 ctgtaattca tagtcacatc aaggtcatca agaccaggaa aaacaagaaa 2400

 gacatactca atcctgattc aagtatggaa acttcaccag actttttctt 2450

 ctaaaatctg gatgtcattg acgataatgt ttatggagat aaggtctaag 2500

 tccctaaaaa aatgtacata tacctggttg aaatacaaca ctatacatac 2550

 acaccaccat atatactagc tgttaatcct atggaatggg ggtattggga 2600

 gtgctttttt aatttttcat agtttttttt taataaaatg gcatattttg 2650

 catctacaac ttctataata agaaaaaata aataaacatt atcttttttg 2700

 tgaaaaaaa 2709

<210> 1878
<211> 729
<212> PRT
<213> Homo sapien

<400> 1878
 Met Gly Lys Lys Tyr Lys Asn Ile Val Leu Leu Lys Gly Leu Glu
   1               5                  10                  15

 Val Ile Asn Asp Tyr His Phe Arg Met Val Lys Ser Leu Leu Ser
                  20                  25                  30

 Asn Asp Leu Lys Leu Asn Leu Lys Met Arg Glu Glu Tyr Asp Lys
                  35                  40                  45

 Ile Gln Ile Ala Asp Leu Met Glu Glu Lys Phe Arg Gly Asp Ala
                  50                  55                  60

 Gly Leu Gly Lys Leu Ile Lys Ile Phe Glu Asp Ile Pro Thr Leu
                  65                  70                  75

 Glu Asp Leu Ala Glu Thr Leu Lys Lys Glu Lys Leu Lys Val Lys
                  80                  85                  90

 Gly Pro Ala Leu Ser Arg Lys Arg Lys Lys Glu Val His Ala Thr
                  95                 100                 105

 Ser Pro Ala Pro Ser Thr Ser Ser Thr Val Lys Thr Glu Gly Ala
                 110                 115                 120

 Glu Ala Thr Pro Gly Ala Gln Lys Arg Lys Lys Ser Thr Lys Glu
                 125                 130                 135

 Lys Ala Gly Pro Lys Gly Ser Lys Val Ser Glu Glu Gln Thr Gln
                 140                 145                 150

 Pro Pro Ser Pro Ala Gly Ala Gly Met Ser Thr Ala Met Gly Arg
                 155                 160                 165

 Ser Pro Ser Pro Lys Thr Ser Leu Ser Ala Pro Pro Asn Ser Ser
                 170                 175                 180

 Ser Thr Glu Asn Pro Lys Thr Val Ala Lys Cys Gln Val Thr Pro
                 185                 190                 195

 Arg Arg Asn Val Leu Gln Lys Arg Pro Val Ile Val Lys Val Leu
                 200                 205                 210

 Ser Thr Thr Lys Pro Phe Glu Tyr Glu Thr Pro Glu Met Glu Lys
                 215                 220                 225

 Lys Ile Met Phe His Ala Thr Val Ala Thr Gln Thr Gln Phe Phe
                 230                 235                 240

 His Val Lys Val Leu Asn Thr Ser Leu Lys Glu Lys Phe Asn Gly
                 245                 250                 255

 Lys Lys Ile Ile Ile Ile Ser Asp Tyr Leu Glu Tyr Asp Ser Leu
                 260                 265                 270

 Leu Glu Val Asn Glu Glu Ser Thr Val Ser Glu Ala Gly Pro Asn
                 275                 280                 285

 Gln Thr Phe Glu Val Pro Asn Lys Ile Ile Asn Arg Ala Lys Glu
                 290                 295                 300

 Thr Leu Lys Ile Asp Ile Leu His Lys Gln Ala Ser Gly Asn Ile
                 305                 310                 315

 Val Tyr Gly Val Phe Met Leu His Lys Lys Thr Val Asn Gln Lys
                 320                 325                 330

 Thr Thr Ile Tyr Glu Ile Gln Asp Asp Arg Gly Lys Met Asp Val
                 335                 340                 345

 Val Gly Thr Gly Gln Cys His Asn Ile Pro Cys Glu Glu Gly Asp
                 350                 355                 360

 Lys Leu Gln Leu Phe Cys Phe Arg Leu Arg Lys Lys Asn Gln Met
                 365                 370                 375

 Ser Lys Leu Ile Ser Glu Met His Ser Phe Ile Gln Ile Lys Lys
                 380                 385                 390

 Lys Thr Asn Pro Arg Asn Asn Asp Pro Lys Ser Met Lys Leu Pro
                 395                 400                 405

 Gln Glu Gln Arg Gln Leu Pro Tyr Pro Ser Glu Ala Ser Thr Thr
                 410                 415                 420

 Phe Pro Glu Ser His Leu Arg Thr Pro Gln Met Pro Pro Thr Thr
                 425                 430                 435

 Pro Ser Ser Ser Phe Phe Thr Lys Lys Ser Glu Asp Thr Ile Ser
                 440                 445                 450

 Lys Met Asn Asp Phe Met Arg Met Gln Ile Leu Lys Glu Gly Ser
                 455                 460                 465

 His Phe Pro Gly Pro Phe Met Thr Ser Ile Gly Pro Ala Glu Ser
                 470                 475                 480

 His Pro His Thr Pro Gln Met Pro Pro Ser Thr Pro Ser Ser Ser
                 485                 490                 495

 Phe Leu Thr Thr Leu Lys Pro Arg Leu Lys Thr Glu Pro Glu Glu
                 500                 505                 510

 Val Ser Ile Glu Asp Ser Ala Gln Ser Asp Leu Lys Glu Val Met
                 515                 520                 525

 Val Leu Asn Ala Thr Glu Ser Phe Val Tyr Glu Pro Lys Glu Gln
                 530                 535                 540

 Lys Lys Met Phe His Ala Thr Val Ala Thr Glu Asn Glu Val Phe
                 545                 550                 555

 Arg Val Lys Val Phe Asn Ile Asp Leu Lys Glu Lys Phe Thr Pro
                 560                 565                 570

 Lys Lys Ile Ile Ala Ile Ala Asn Tyr Val Cys Arg Asn Gly Phe
                 575                 580                 585

 Leu Glu Val Tyr Pro Phe Thr Leu Val Ala Asp Val Asn Ala Asp
                 590                 595                 600

 Arg Asn Met Glu Ile Pro Lys Gly Leu Ile Arg Ser Ala Ser Val
                 605                 610                 615

 Thr Pro Lys Ile Asn Gln Leu Cys Ser Gln Thr Lys Gly Ser Phe
                 620                 625                 630

 Val Asn Gly Val Phe Glu Val His Lys Lys Asn Val Arg Gly Glu
                 635                 640                 645

 Phe Thr Tyr Tyr Glu Ile Gln Asp Asn Thr Gly Lys Met Glu Val
                 650                 655                 660

 Val Val His Gly Arg Leu Asn Thr Ile Asn Cys Glu Glu Gly Asp
                 665                 670                 675

 Lys Leu Lys Leu Thr Ser Phe Glu Leu Ala Pro Lys Ser Gly Asn
                 680                 685                 690

 Thr Gly Glu Leu Arg Ser Val Ile His Ser His Ile Lys Val Ile
                 695                 700                 705

 Lys Thr Arg Lys Asn Lys Lys Asp Ile Leu Asn Pro Asp Ser Ser
                 710                 715                 720

 Met Glu Thr Ser Pro Asp Phe Phe Phe
                 725

<210> 1879
<211> 4205
<212> DNA
<213> Homo sapien

<400> 1879
 ctccctcgct ccctccctgc gcgccgcctc tcactcacag cctcccttcc 50

 ttctttctcc ctccgcctcc cgagcaccag cgcgctctga gctgccccca 100

 gggtccctcc cccgccgcca gcagcccatt tggagggagg aagtaaggga 150

 agaggagagg aaggggagcc ggaccgacta cccagacaga gccggtgaat 200

 gggtttgtgg tgacccccgc cccccacccc accctccctt cccacccgac 250

 ccccaacccc catccccagt tcgagccgcc gcccgaaagg ccgggccgtc 300

 gtcttaggag gagtcgccgc cgccgccacc tccgccatgg agctgatcac 350

 cattctcgag aagaccgtgt ctcccgatcg gctggagctg gaagcggcgc 400

 agaagttcct ggagcgtgcg gccgtggaga acctgcccac tttccttgtg 450

 gaactgtcca gagtgctggc aaatccagga aacagtcagg ttgccagagt 500

 tgcagctggt ctacaaatca agaactcttt gacatctaaa gatccagata 550

 tcaaggcaca atatcagcag aggtggcttg ctattgatgc taatgctcga 600

 cgagaagtca agaactatgt tttgcagaca ttgggtacag aaacttaccg 650

 gcctagttct gcctcacagt gtgtggctgg tattgcttgt gcagagatcc 700

 cagtaaacca gtggccagaa ctcattcctc agctggtggc caatgtcaca 750

 aaccccaaca gcacagagca catgaaggag tcgacattgg aagccatcgg 800

 ttatatttgc caagatatag acccagagca gctacaagat aaatccaatg 850

 agattctgac tgccataatc caggggatga ggaaagaaga gcctagtaat 900

 aatgtgaagc tagctgctac gaatgcactc ctgaactcat tggagttcac 950

 caaagcaaac tttgataaag agtctgaaag gcactttatt atgcaggtgg 1000

 tctgtgaagc cacacagtgt ccagatacga gggtacgagt ggctgcttta 1050

 cagaatctgg tgaagataat gtccttatat tatcagtaca tggagacata 1100

 tatgggtcct gctctttttg caatcacaat cgaagcaatg aaaagtgaca 1150

 ttgatgaggt ggctttacaa gggatagaat tctggtccaa tgtctgtgat 1200

 gaggaaatgg atttggccat tgaagcttca gaggcagcag aacaaggacg 1250

 gccccctgag cacaccagca agttttatgc gaagggagca ctacagtatc 1300

 tggttccaat cctcacacag acactaacta aacaggacga aaatgatgat 1350

 gacgatgact ggaacccctg caaagcagca ggggtgtgcc tcatgcttct 1400

 ggccacctgc tgtgaagatg acattgtccc acatgtcctc cccttcatta 1450

 aagaacacat caagaaccca gattggcggt accgggatgc agcagtgatg 1500

 gcttttggtt gtatcttgga aggaccagag cccagtcagc tcaaaccact 1550

 agttatacag gctatgccca ccctaataga attaatgaaa gaccccagtg 1600

 tagttgttcg agatacagct gcatggactg taggcagaat ttgtgagctg 1650

 cttcctgaag ctgccatcaa tgatgtctac ttggctcccc tgctacagtg 1700

 tctgattgag ggtctcagtg ctgaacccag agtggcttca aatgtgtgct 1750

 gggctttctc cagtctggct gaagctgctt atgaagctgc agacgttgct 1800

 gatgatcagg aagaaccagc tacttactgc ttatcttctt catttgaact 1850

 catagttcag aagctcctag agactacaga cagacctgat ggacaccaga 1900

 acaacctgag gagttctgca tatgaatctc tgatggaaat tgtgaaaaac 1950

 agtgccaagg attgttatcc tgctgtccag aaaacgactt tggtcatcat 2000

 ggaacgactg caacaggttc ttcagatgga gtcacatatc cagagcacat 2050

 ccgatagaat ccagttcaat gaccttcagt ctttactctg tgcaactctt 2100

 cagaatgttc ttcggaaagt gcaacatcaa gatgctttgc agatctctga 2150

 tgtggttatg gcctccctgt taaggatgtt ccaaagcaca gctgggtctg 2200

 ggggagtaca agaggatgcc ctgatggcag ttagcacact ggtggaagtg 2250

 ttgggtggtg aattcctcaa gtacatggag gcctttaaac ccttcctggg 2300

 cattggatta aaaaattatg ctgaatacca ggtttgtttg gcagctgtgg 2350

 gcttagtggg agacttgtgc cgtgccctgc aatccaacat catacctttc 2400

 tgtgacgagg tgatgcagct gcttctggaa aatttgggga atgagaacgt 2450

 ccacaggtct gtgaagccgc agattctgtc agtgtttggt gatattgccc 2500

 ttgctattgg aggagagttt aaaaaatact tagaggttgt attgaatact 2550

 cttcagcagg cctcccaagc ccaggtggac aagtcagact atgacatggt 2600

 ggattatctg aatgagctaa gggaaagctg cttggaagcc tatactggaa 2650

 tcgtccaggg attaaagggg gatcaggaga acgtacaccc ggatgtgatg 2700

 ctggtacaac ccagagtaga atttattctg tctttcattg accacattgc 2750

 tggagatgag gatcacacag atggagtagt agcttgtgct gctggactaa 2800

 taggggactt atgtacagca tttgggaagg atgtactgaa attagtagaa 2850

 gctaggccaa tgatccatga attgttaact gaagggcgga gatcgaagac 2900

 taacaaagca aaaacccttg ctacatgggc aacaaaagaa ctgaggaaac 2950

 tgaagaacca agcttgatct gttaccattg ggatgataac ctgaggaccc 3000

 ccactggaaa tctcccatct tttgaaaaac ctggaagtga ggagtgtgca 3050

 cggatgctga atgtttggga atgagaggat gagtgagtga ggcttgaaaa 3100

 cacaccacat tgaaaatcct gccacagcag cagccgcagc cgccaacagc 3150

 agcgctgtta gtgagctaag taagcactga cttcgtagaa aaccataaca 3200

 tcggccatct tggaaaagag aaaaacaatg gagttactta tttaaaaaaa 3250

 aagaaagaaa gttatctctt cccaggagag gctagaagta gcttttctgt 3300

 cttttggcca gtgccgagtg gaatgcctgg tttgggggag gaggagggac 3350

 tgggttcagc tgtggtgctt tgttgtaaaa ggcagcctgg cctttgctac 3400

 tgaggagaaa gatggagcct gggtctcaag cccaccttcg ctgtaccttt 3450

 gccacatggt actgtatgct tgccagctag aaggagggtc agggattttt 3500

 tacagtctga gaatgagtgt gtgtgagtga ggcggtatcc acattctcaa 3550

 cttcaagtca ttgcagtttc tttttcccag aaaacaaggg gttagatgtt 3600

 gcatttcata aaactaaccg aagttctgtc tactgatgca gcacaagaga 3650

 tgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aacacacaca cagaggaaag 3700

 acgctcttta ggttttgttt tgtttttttt ttttggtttt gttttttgtt 3750

 ttttttactc tagggaaaac actgacgaat ggtcagagct cctatcctga 3800

 tcttttcatc aaggcgcctt tcctaataat atggttcaac tgtgaatgta 3850

 gaagtggggg ggagggggga gaaaaagaaa actctggcgt tagaggatat 3900

 agaaaaatat aagtacaatt gttacaaata acgcagactt caaaaacaaa 3950

 aaaatcacaa cccaaacaaa ccaaaattta aatgatcaga attggcagca 4000

 caaagaaaac gccctctcct gacttgtatt gtggcagtct gaacgccccc 4050

 agaaaattgt gccaaagagt ttagaaaaat aaatatacaa taaaagtaaa 4100

 cacatacaca caaaacagca aacttcaggt aactattttg gattgcaaac 4150

 aggataaatt aaatgttcaa acaatctgat aaaataacca tttggaaact 4200

 gaaaa 4205

<210> 1880
<211> 876
<212> PRT
<213> Homo sapien

<400> 1880
 Met Glu Leu Ile Thr Ile Leu Glu Lys Thr Val Ser Pro Asp Arg
   1               5                  10                  15

 Leu Glu Leu Glu Ala Ala Gln Lys Phe Leu Glu Arg Ala Ala Val
                  20                  25                  30

 Glu Asn Leu Pro Thr Phe Leu Val Glu Leu Ser Arg Val Leu Ala
                  35                  40                  45

 Asn Pro Gly Asn Ser Gln Val Ala Arg Val Ala Ala Gly Leu Gln
                  50                  55                  60

 Ile Lys Asn Ser Leu Thr Ser Lys Asp Pro Asp Ile Lys Ala Gln
                  65                  70                  75

 Tyr Gln Gln Arg Trp Leu Ala Ile Asp Ala Asn Ala Arg Arg Glu
                  80                  85                  90

 Val Lys Asn Tyr Val Leu Gln Thr Leu Gly Thr Glu Thr Tyr Arg
                  95                 100                 105

 Pro Ser Ser Ala Ser Gln Cys Val Ala Gly Ile Ala Cys Ala Glu
                 110                 115                 120

 Ile Pro Val Asn Gln Trp Pro Glu Leu Ile Pro Gln Leu Val Ala
                 125                 130                 135

 Asn Val Thr Asn Pro Asn Ser Thr Glu His Met Lys Glu Ser Thr
                 140                 145                 150

 Leu Glu Ala Ile Gly Tyr Ile Cys Gln Asp Ile Asp Pro Glu Gln
                 155                 160                 165

 Leu Gln Asp Lys Ser Asn Glu Ile Leu Thr Ala Ile Ile Gln Gly
                 170                 175                 180

 Met Arg Lys Glu Glu Pro Ser Asn Asn Val Lys Leu Ala Ala Thr
                 185                 190                 195

 Asn Ala Leu Leu Asn Ser Leu Glu Phe Thr Lys Ala Asn Phe Asp
                 200                 205                 210

 Lys Glu Ser Glu Arg His Phe Ile Met Gln Val Val Cys Glu Ala
                 215                 220                 225

 Thr Gln Cys Pro Asp Thr Arg Val Arg Val Ala Ala Leu Gln Asn
                 230                 235                 240

 Leu Val Lys Ile Met Ser Leu Tyr Tyr Gln Tyr Met Glu Thr Tyr
                 245                 250                 255

 Met Gly Pro Ala Leu Phe Ala Ile Thr Ile Glu Ala Met Lys Ser
                 260                 265                 270

 Asp Ile Asp Glu Val Ala Leu Gln Gly Ile Glu Phe Trp Ser Asn
                 275                 280                 285

 Val Cys Asp Glu Glu Met Asp Leu Ala Ile Glu Ala Ser Glu Ala
                 290                 295                 300

 Ala Glu Gln Gly Arg Pro Pro Glu His Thr Ser Lys Phe Tyr Ala
                 305                 310                 315

 Lys Gly Ala Leu Gln Tyr Leu Val Pro Ile Leu Thr Gln Thr Leu
                 320                 325                 330

 Thr Lys Gln Asp Glu Asn Asp Asp Asp Asp Asp Trp Asn Pro Cys
                 335                 340                 345

 Lys Ala Ala Gly Val Cys Leu Met Leu Leu Ala Thr Cys Cys Glu
                 350                 355                 360

 Asp Asp Ile Val Pro His Val Leu Pro Phe Ile Lys Glu His Ile
                 365                 370                 375

 Lys Asn Pro Asp Trp Arg Tyr Arg Asp Ala Ala Val Met Ala Phe
                 380                 385                 390

 Gly Cys Ile Leu Glu Gly Pro Glu Pro Ser Gln Leu Lys Pro Leu
                 395                 400                 405

 Val Ile Gln Ala Met Pro Thr Leu Ile Glu Leu Met Lys Asp Pro
                 410                 415                 420

 Ser Val Val Val Arg Asp Thr Ala Ala Trp Thr Val Gly Arg Ile
                 425                 430                 435

 Cys Glu Leu Leu Pro Glu Ala Ala Ile Asn Asp Val Tyr Leu Ala
                 440                 445                 450

 Pro Leu Leu Gln Cys Leu Ile Glu Gly Leu Ser Ala Glu Pro Arg
                 455                 460                 465

 Val Ala Ser Asn Val Cys Trp Ala Phe Ser Ser Leu Ala Glu Ala
                 470                 475                 480

 Ala Tyr Glu Ala Ala Asp Val Ala Asp Asp Gln Glu Glu Pro Ala
                 485                 490                 495

 Thr Tyr Cys Leu Ser Ser Ser Phe Glu Leu Ile Val Gln Lys Leu
                 500                 505                 510

 Leu Glu Thr Thr Asp Arg Pro Asp Gly His Gln Asn Asn Leu Arg
                 515                 520                 525

 Ser Ser Ala Tyr Glu Ser Leu Met Glu Ile Val Lys Asn Ser Ala
                 530                 535                 540

 Lys Asp Cys Tyr Pro Ala Val Gln Lys Thr Thr Leu Val Ile Met
                 545                 550                 555

 Glu Arg Leu Gln Gln Val Leu Gln Met Glu Ser His Ile Gln Ser
                 560                 565                 570

 Thr Ser Asp Arg Ile Gln Phe Asn Asp Leu Gln Ser Leu Leu Cys
                 575                 580                 585

 Ala Thr Leu Gln Asn Val Leu Arg Lys Val Gln His Gln Asp Ala
                 590                 595                 600

 Leu Gln Ile Ser Asp Val Val Met Ala Ser Leu Leu Arg Met Phe
                 605                 610                 615

 Gln Ser Thr Ala Gly Ser Gly Gly Val Gln Glu Asp Ala Leu Met
                 620                 625                 630

 Ala Val Ser Thr Leu Val Glu Val Leu Gly Gly Glu Phe Leu Lys
                 635                 640                 645

 Tyr Met Glu Ala Phe Lys Pro Phe Leu Gly Ile Gly Leu Lys Asn
                 650                 655                 660

 Tyr Ala Glu Tyr Gln Val Cys Leu Ala Ala Val Gly Leu Val Gly
                 665                 670                 675

 Asp Leu Cys Arg Ala Leu Gln Ser Asn Ile Ile Pro Phe Cys Asp
                 680                 685                 690

 Glu Val Met Gln Leu Leu Leu Glu Asn Leu Gly Asn Glu Asn Val
                 695                 700                 705

 His Arg Ser Val Lys Pro Gln Ile Leu Ser Val Phe Gly Asp Ile
                 710                 715                 720

 Ala Leu Ala Ile Gly Gly Glu Phe Lys Lys Tyr Leu Glu Val Val
                 725                 730                 735

 Leu Asn Thr Leu Gln Gln Ala Ser Gln Ala Gln Val Asp Lys Ser
                 740                 745                 750

 Asp Tyr Asp Met Val Asp Tyr Leu Asn Glu Leu Arg Glu Ser Cys
                 755                 760                 765

 Leu Glu Ala Tyr Thr Gly Ile Val Gln Gly Leu Lys Gly Asp Gln
                 770                 775                 780

 Glu Asn Val His Pro Asp Val Met Leu Val Gln Pro Arg Val Glu
                 785                 790                 795

 Phe Ile Leu Ser Phe Ile Asp His Ile Ala Gly Asp Glu Asp His
                 800                 805                 810

 Thr Asp Gly Val Val Ala Cys Ala Ala Gly Leu Ile Gly Asp Leu
                 815                 820                 825

 Cys Thr Ala Phe Gly Lys Asp Val Leu Lys Leu Val Glu Ala Arg
                 830                 835                 840

 Pro Met Ile His Glu Leu Leu Thr Glu Gly Arg Arg Ser Lys Thr
                 845                 850                 855

 Asn Lys Ala Lys Thr Leu Ala Thr Trp Ala Thr Lys Glu Leu Arg
                 860                 865                 870

 Lys Leu Lys Asn Gln Ala
                 875

<210> 1881
<211> 4212
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3879-3880
<223> Unknown base

<400> 1881
 ctccctcgct ccctccctgc gcgccgcctc tcactcacag cctcccttcc 50

 ttctttctcc ctccgcctcc cgagcaccag cgcgctctga gctgccccca 100

 gggtcccctc ccccgccgcc agcagcccat ttggagggag gaagtaaggg 150

 aagaggagag gaaggggagc cggaccgact acccagacag agccggtgaa 200

 tgggtttgtg gtgacccccg ccccccaccc caccctccct tcccacccga 250

 cccccaaccc ccatccccag ttcgagccgc cgcccgaaag gccgggccgt 300

 cgtcttagga ggagtcgccg ccgccgccac ctccgccatg gagctgatca 350

 ccattctcga gaagaccgtg tctcccgatc ggctggagct ggaagcggcg 400

 cagaagttcc tggagcgtgc ggccgtggag aacctgccca ctttccttgt 450

 ggaactgtcc agagtgctgg caaatccagg aaacagtcag gttgccagag 500

 ttgcagctgg tctacaaatc aagaactctt tgacatctaa agatccagat 550

 atcaaggcac aatatcagca gaggtggctt gctattgatg ctaatgctcg 600

 acgagaagtc aagaactatg ttttgcagac attgggtaca gaaacttacc 650

 ggcctagttc tgcctcacag tgtgtggctg gtattgcttg tgcagagatc 700

 ccagtaaacc agtggccaga actcattcct cagctggtgg ccaatgtcac 750

 aaaccccaac agcacagagc acatgaagga gtcgacattg gaagccatcg 800

 gttatatttg ccaagatata gacccagagc agctacaaga taaatccaat 850

 gagattctga ctgccataat ccaggggatg aggaaagaag agcctagtaa 900

 taatgtgaag ctagctgcta caaatgcact cctgaactca ttggagttca 950

 ccaaagcaaa ctttgataaa gagtctgaaa ggcactttat tatgcaggtg 1000

 gtctgtgaag ccacacagtg tccagatacg agggtacgag tggctgcttt 1050

 acagaatctg gtgaagataa tgtccttata ttatcagtac atggagacat 1100

 atatgggtcc tgctcttttt gcaatcacaa tcgaagcaat gaaaagtgac 1150

 attgatgagg tggctttaca agggatagaa ttctggtcca atgtctgtga 1200

 tgaggaaatg gatttggcca ttgaagcttc agaggcagca gaacaaggac 1250

 ggccccctga gcacaccagc aagttttatg cgaagggagc actacagtat 1300

 ctggttccaa tcctcacaca gacactaact aaacaggacg aaaatgatga 1350

 tgacgatgac tggaacccct gcaaagcagc aggggtgtgc ctcatgcttc 1400

 tggccacctg ctgtgaagat gacattgtcc cacatgtcct ccccttcatt 1450

 aaagaacaca tcaagaaccc agattggcgg taccgggatg cagcagtgat 1500

 ggcttttggt tgtatcttgg aaggaccaga gcccagtcag ctcaaaccac 1550

 tagttataca ggctatgccc accctaatag aattaatgaa agaccccagt 1600

 gtagttgttc gagatacagc tgcatggact gtaggcagaa tttgtgagct 1650

 gcttcctgaa gctgccatca atgatgtcta cttggctccc ctgctacagt 1700

 gtctgattga gggtctcagt gctgaaccca gagtggcttc aaatgtgtgc 1750

 tgggctttct ccagtctggc tgaagctgct tatgaagctg cagacgttgc 1800

 tgatgatcag gaagaaccag ctacttactg cttatcttct tcatttgaac 1850

 tcatagttca gaagctccta gagactacag acagacctga tggacaccag 1900

 aacaacctga ggagttctgc atatgaatct ctgatggaaa ttgtgaaaaa 1950

 cagtgccaag gattgttacc ctgctgtcca gaaaacgact ttggtcatca 2000

 tggaacgact gcaacaggtt cttcagatgg agtcacatat ccagagcaca 2050

 tccgatagaa tccagttcaa tgaccttcag tctttactct gtgcaactct 2100

 tcagaatgtt cttcggaaag tgcaacatca agatgctttg cagatctctg 2150

 atgtggttat ggcctccctg ttaaggatgt tccaaagcac agctgggtct 2200

 gggggagtac aagaggatgc cctgatggca gttagcacac tggtggaagt 2250

 gttgggtggt gaattcctca agtacatgga ggcctttaaa cccttcctgg 2300

 gcattggatt aaaaaattat gctgaatacc aggtttgttt ggcagctgtg 2350

 ggcttagtgg gagacttgtg ccgtgccctg caatccaaca tcataccttt 2400

 ctgtgacgag gtgatgcagc tgcttctgga aaatttgggg aatgagaacg 2450

 tccacaggtc tgtgaagccg cagattctgt cagtgtttgg tgatattgcc 2500

 cttgctattg gaggagagtt taaaaaatac ttagaggttg tattgaatac 2550

 tcttcagcag gcctcccaag cccaggtgga caagtcagac tatgacatgg 2600

 tggattatct gaatgagcta agggaaagct gcttggaagc ctatactgga 2650

 atcgtccagg gattaaaggg ggatcaggag aacgtacacc cggatgtgat 2700

 gctggtacaa cccagagtag aatttattct gtctttcatt gaccacattg 2750

 ctggagatga ggatcacaca gatggagtag tagcttgtgc tgctggacta 2800

 ataggggact tatgtacagc atttgggaag gatgtactga aattagtaga 2850

 agctaggcca atgatccatg aattgttaac tgaagggcgg agatcgaaga 2900

 ctaacaaagc aaaaaccctt gctacatggg caacaaaaga actgaggaaa 2950

 ctgaagaacc aagcttgatc tgttaccatt gggatgataa cctgaggacc 3000

 cccactggaa atctcccatc ttttgaaaaa cctggaagtg aggagtgtgc 3050

 acggatgctg aatgtttggg aatgagagga tgagtgagtg aggcttgaaa 3100

 acacaccaca ttgaaaatcc tgccacagca gcagccgcag ccgccaacag 3150

 cagcgctgtt agtgagctaa gtaagcactg acttcgtaga aaaccataac 3200

 atcggccatc ttggaaaaga gaaaaacaat ggagttactt atttaaaaaa 3250

 aaagaaagaa agttatctct tcccaggaga ggctagaagt agcttttctg 3300

 tcttttggcc agtgccgagt ggaatgcctg gtttcgggga ggaggaggga 3350

 ctgggttcag ctgtggtgct ttgttgtaaa aggcagcctg gcctttgcta 3400

 ctgaggagaa agatggagcc tgggtctcaa gcccaccttc gctgtacctt 3450

 tgccacatgg tactgtatgc ttgccagcta gaaggagggt cagggttttt 3500

 tacagtctga gaatgagtgt gtgtgagtga ggcggtatcc acattctcaa 3550

 cttcaagtca ttgctgtttc tttttcccag aaaacaaggg gttagatgtt 3600

 gcatttcata aaactaaccg aagttctgtc tactgatgca gcacaagaga 3650

 tgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaacacaca aaaaaacaca 3700

 cacacagagg aaagacgctc tttaggtttt gttttgtttt tttttttttg 3750

 gttttgtttt ttgttttttt ttttactcta gggaaaacac tgacgaatgg 3800

 tcagagctcc tatcctgatc ttttcatcaa ggcgcctttc ctaataatat 3850

 ggttcaactg tgaatgtaga agtgggggnn aggggggaga aaaagaaaac 3900

 tctggcgtta gaggatataa aaaaatataa gtacaattgt tacaaataac 3950

 gcagacttca aaaacaaaaa aatcacaacc caaacaaacc aaaatttaaa 4000

 tgatcagaat tggcagcaca aagaaaacgc cctctcctga cttgtattgt 4050

 ggcagtctga acgcccccag aaaattgtgc caaagagttt agaaaaataa 4100

 atatacaata aaagtaaaca catacacaca aaacagcaaa cttcaggtaa 4150

 ctattttgga ttgcaaacag gataattaaa tgttcaaaca atctgataaa 4200

 ataaccattt gg 4212

<210> 1882
<211> 876
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3879-3880
<223> Unknown amino acid

<400> 1882
 Met Glu Leu Ile Thr Ile Leu Glu Lys Thr Val Ser Pro Asp Arg
   1               5                  10                  15

 Leu Glu Leu Glu Ala Ala Gln Lys Phe Leu Glu Arg Ala Ala Val
                  20                  25                  30

 Glu Asn Leu Pro Thr Phe Leu Val Glu Leu Ser Arg Val Leu Ala
                  35                  40                  45

 Asn Pro Gly Asn Ser Gln Val Ala Arg Val Ala Ala Gly Leu Gln
                  50                  55                  60

 Ile Lys Asn Ser Leu Thr Ser Lys Asp Pro Asp Ile Lys Ala Gln
                  65                  70                  75

 Tyr Gln Gln Arg Trp Leu Ala Ile Asp Ala Asn Ala Arg Arg Glu
                  80                  85                  90

 Val Lys Asn Tyr Val Leu Gln Thr Leu Gly Thr Glu Thr Tyr Arg
                  95                 100                 105

 Pro Ser Ser Ala Ser Gln Cys Val Ala Gly Ile Ala Cys Ala Glu
                 110                 115                 120

 Ile Pro Val Asn Gln Trp Pro Glu Leu Ile Pro Gln Leu Val Ala
                 125                 130                 135

 Asn Val Thr Asn Pro Asn Ser Thr Glu His Met Lys Glu Ser Thr
                 140                 145                 150

 Leu Glu Ala Ile Gly Tyr Ile Cys Gln Asp Ile Asp Pro Glu Gln
                 155                 160                 165

 Leu Gln Asp Lys Ser Asn Glu Ile Leu Thr Ala Ile Ile Gln Gly
                 170                 175                 180

 Met Arg Lys Glu Glu Pro Ser Asn Asn Val Lys Leu Ala Ala Thr
                 185                 190                 195

 Asn Ala Leu Leu Asn Ser Leu Glu Phe Thr Lys Ala Asn Phe Asp
                 200                 205                 210

 Lys Glu Ser Glu Arg His Phe Ile Met Gln Val Val Cys Glu Ala
                 215                 220                 225

 Thr Gln Cys Pro Asp Thr Arg Val Arg Val Ala Ala Leu Gln Asn
                 230                 235                 240

 Leu Val Lys Ile Met Ser Leu Tyr Tyr Gln Tyr Met Glu Thr Tyr
                 245                 250                 255

 Met Gly Pro Ala Leu Phe Ala Ile Thr Ile Glu Ala Met Lys Ser
                 260                 265                 270

 Asp Ile Asp Glu Val Ala Leu Gln Gly Ile Glu Phe Trp Ser Asn
                 275                 280                 285

 Val Cys Asp Glu Glu Met Asp Leu Ala Ile Glu Ala Ser Glu Ala
                 290                 295                 300

 Ala Glu Gln Gly Arg Pro Pro Glu His Thr Ser Lys Phe Tyr Ala
                 305                 310                 315

 Lys Gly Ala Leu Gln Tyr Leu Val Pro Ile Leu Thr Gln Thr Leu
                 320                 325                 330

 Thr Lys Gln Asp Glu Asn Asp Asp Asp Asp Asp Trp Asn Pro Cys
                 335                 340                 345

 Lys Ala Ala Gly Val Cys Leu Met Leu Leu Ala Thr Cys Cys Glu
                 350                 355                 360

 Asp Asp Ile Val Pro His Val Leu Pro Phe Ile Lys Glu His Ile
                 365                 370                 375

 Lys Asn Pro Asp Trp Arg Tyr Arg Asp Ala Ala Val Met Ala Phe
                 380                 385                 390

 Gly Cys Ile Leu Glu Gly Pro Glu Pro Ser Gln Leu Lys Pro Leu
                 395                 400                 405

 Val Ile Gln Ala Met Pro Thr Leu Ile Glu Leu Met Lys Asp Pro
                 410                 415                 420

 Ser Val Val Val Arg Asp Thr Ala Ala Trp Thr Val Gly Arg Ile
                 425                 430                 435

 Cys Glu Leu Leu Pro Glu Ala Ala Ile Asn Asp Val Tyr Leu Ala
                 440                 445                 450

 Pro Leu Leu Gln Cys Leu Ile Glu Gly Leu Ser Ala Glu Pro Arg
                 455                 460                 465

 Val Ala Ser Asn Val Cys Trp Ala Phe Ser Ser Leu Ala Glu Ala
                 470                 475                 480

 Ala Tyr Glu Ala Ala Asp Val Ala Asp Asp Gln Glu Glu Pro Ala
                 485                 490                 495

 Thr Tyr Cys Leu Ser Ser Ser Phe Glu Leu Ile Val Gln Lys Leu
                 500                 505                 510

 Leu Glu Thr Thr Asp Arg Pro Asp Gly His Gln Asn Asn Leu Arg
                 515                 520                 525

 Ser Ser Ala Tyr Glu Ser Leu Met Glu Ile Val Lys Asn Ser Ala
                 530                 535                 540

 Lys Asp Cys Tyr Pro Ala Val Gln Lys Thr Thr Leu Val Ile Met
                 545                 550                 555

 Glu Arg Leu Gln Gln Val Leu Gln Met Glu Ser His Ile Gln Ser
                 560                 565                 570

 Thr Ser Asp Arg Ile Gln Phe Asn Asp Leu Gln Ser Leu Leu Cys
                 575                 580                 585

 Ala Thr Leu Gln Asn Val Leu Arg Lys Val Gln His Gln Asp Ala
                 590                 595                 600

 Leu Gln Ile Ser Asp Val Val Met Ala Ser Leu Leu Arg Met Phe
                 605                 610                 615

 Gln Ser Thr Ala Gly Ser Gly Gly Val Gln Glu Asp Ala Leu Met
                 620                 625                 630

 Ala Val Ser Thr Leu Val Glu Val Leu Gly Gly Glu Phe Leu Lys
                 635                 640                 645

 Tyr Met Glu Ala Phe Lys Pro Phe Leu Gly Ile Gly Leu Lys Asn
                 650                 655                 660

 Tyr Ala Glu Tyr Gln Val Cys Leu Ala Ala Val Gly Leu Val Gly
                 665                 670                 675

 Asp Leu Cys Arg Ala Leu Gln Ser Asn Ile Ile Pro Phe Cys Asp
                 680                 685                 690

 Glu Val Met Gln Leu Leu Leu Glu Asn Leu Gly Asn Glu Asn Val
                 695                 700                 705

 His Arg Ser Val Lys Pro Gln Ile Leu Ser Val Phe Gly Asp Ile
                 710                 715                 720

 Ala Leu Ala Ile Gly Gly Glu Phe Lys Lys Tyr Leu Glu Val Val
                 725                 730                 735

 Leu Asn Thr Leu Gln Gln Ala Ser Gln Ala Gln Val Asp Lys Ser
                 740                 745                 750

 Asp Tyr Asp Met Val Asp Tyr Leu Asn Glu Leu Arg Glu Ser Cys
                 755                 760                 765

 Leu Glu Ala Tyr Thr Gly Ile Val Gln Gly Leu Lys Gly Asp Gln
                 770                 775                 780

 Glu Asn Val His Pro Asp Val Met Leu Val Gln Pro Arg Val Glu
                 785                 790                 795

 Phe Ile Leu Ser Phe Ile Asp His Ile Ala Gly Asp Glu Asp His
                 800                 805                 810

 Thr Asp Gly Val Val Ala Cys Ala Ala Gly Leu Ile Gly Asp Leu
                 815                 820                 825

 Cys Thr Ala Phe Gly Lys Asp Val Leu Lys Leu Val Glu Ala Arg
                 830                 835                 840

 Pro Met Ile His Glu Leu Leu Thr Glu Gly Arg Arg Ser Lys Thr
                 845                 850                 855

 Asn Lys Ala Lys Thr Leu Ala Thr Trp Ala Thr Lys Glu Leu Arg
                 860                 865                 870

 Lys Leu Lys Asn Gln Ala
                 875

<210> 1883
<211> 1577
<212> DNA
<213> Homo sapien

<400> 1883
 ggcacgaggc tgctgtttgt ctacttcctc ctgcttcccc gccgccgccg 50

 ccgccatcat gagggaaatc gtgcacttgc aggccgggca gtgcggcaac 100

 caaatcggcg ccaagttttg ggaggtgatc agcgatgagc acggcatcga 150

 ccccacgggc acctaccacg gggacagcga cctgcagctg gaacgcatca 200

 acgtgtacta caatgaggcc accggcggca agtacgtgcc ccgcgccgtg 250

 ctcgtggatc tggagcccgg caccatggac tccgtgcgct cggggccctt 300

 cgggcagatc ttccggccgg acaacttcgt tttcggtcag agtggtgctg 350

 ggaacaactg ggccaagggg cactacacag aaggcgcgga gctggtggac 400

 tcggtgctgg atgttgtgag aaaggaggct gagagctgtg actgcctgca 450

 gggtttccag ctgacccact ccctgggtgg ggggactggg tctgggatgg 500

 gtaccctcct catcagcaag atccgggagg agtacccaga caggatcatg 550

 aacacgttta gtgtggtgcc ttcgcccaaa gtgtcagaca cagtggtgga 600

 gccctacaac gccaccctct cagtccacca gctcgtagaa aacacagacg 650

 agacctactg cattgataac gaagctctct acgacatttg cttcagaacc 700

 ctaaagctga ccacgcccac ctatggtgac ctgaaccacc tggtgtctgc 750

 taccatgagt ggggtcacca cctgcctgcg cttcccaggc cagctcaatg 800

 ctgacctgcg gaagctggct gtgaacatgg tcccgtttcc ccggctgcac 850

 ttcttcatgc ccggctttgc cccactgacc agccggggca gccagcagta 900

 ccgggcgctg accgtgcccg agctcaccca gcagatgttt gatgccaaga 950

 acatgatggc tgcctgcgac ccccgccatg gccgctacct gacggttgcc 1000

 gccgtgttca ggggccgcat gtccatgaag gaggtggatg agcaaatgct 1050

 taatgtccaa aacaaaaaca gcagctattt tgttgagtgg atccccaaca 1100

 atgtgaaaac ggctgtctgt gacatcccac ctcgggggct aaaaatgtcc 1150

 gccaccttca ttggcaacag cacggccatc caggagctgt tcaagcgcat 1200

 ctccgagcag ttcacggcca tgttccggcg caaggccttc ctgcactggt 1250

 acacgggcga gggcatggac gagatggagt tcaccgaggc cgagagcaac 1300

 atgaatgacc tggtgtccga gtaccagcag taccaggatg ccacagccga 1350

 ggaggagggc gagttcgagg aggaggctga ggaggaggtg gcctagagcc 1400

 ttcagtcact ggggaaagca gggaagcagt gtgaactctt tattcactcc 1450

 cagcctgtcc tgtggcctgt cccactgtgt gcacttgctg ttttccctgt 1500

 ccacatccat gctgtacaga caccaccatt aaagcatttt catagtgaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 1577

<210> 1884
<211> 445
<212> PRT
<213> Homo sapien

<400> 1884
 Met Arg Glu Ile Val His Leu Gln Ala Gly Gln Cys Gly Asn Gln
   1               5                  10                  15

 Ile Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile
                  20                  25                  30

 Asp Pro Thr Gly Thr Tyr His Gly Asp Ser Asp Leu Gln Leu Glu
                  35                  40                  45

 Arg Ile Asn Val Tyr Tyr Asn Glu Ala Thr Gly Gly Lys Tyr Val
                  50                  55                  60

 Pro Arg Ala Val Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser
                  65                  70                  75

 Val Arg Ser Gly Pro Phe Gly Gln Ile Phe Arg Pro Asp Asn Phe
                  80                  85                  90

 Val Phe Gly Gln Ser Gly Ala Gly Asn Asn Trp Ala Lys Gly His
                  95                 100                 105

 Tyr Thr Glu Gly Ala Glu Leu Val Asp Ser Val Leu Asp Val Val
                 110                 115                 120

 Arg Lys Glu Ala Glu Ser Cys Asp Cys Leu Gln Gly Phe Gln Leu
                 125                 130                 135

 Thr His Ser Leu Gly Gly Gly Thr Gly Ser Gly Met Gly Thr Leu
                 140                 145                 150

 Leu Ile Ser Lys Ile Arg Glu Glu Tyr Pro Asp Arg Ile Met Asn
                 155                 160                 165

 Thr Phe Ser Val Val Pro Ser Pro Lys Val Ser Asp Thr Val Val
                 170                 175                 180

 Glu Pro Tyr Asn Ala Thr Leu Ser Val His Gln Leu Val Glu Asn
                 185                 190                 195

 Thr Asp Glu Thr Tyr Cys Ile Asp Asn Glu Ala Leu Tyr Asp Ile
                 200                 205                 210

 Cys Phe Arg Thr Leu Lys Leu Thr Thr Pro Thr Tyr Gly Asp Leu
                 215                 220                 225

 Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Cys Leu
                 230                 235                 240

 Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val
                 245                 250                 255

 Asn Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe
                 260                 265                 270

 Ala Pro Leu Thr Ser Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr
                 275                 280                 285

 Val Pro Glu Leu Thr Gln Gln Met Phe Asp Ala Lys Asn Met Met
                 290                 295                 300

 Ala Ala Cys Asp Pro Arg His Gly Arg Tyr Leu Thr Val Ala Ala
                 305                 310                 315

 Val Phe Arg Gly Arg Met Ser Met Lys Glu Val Asp Glu Gln Met
                 320                 325                 330

 Leu Asn Val Gln Asn Lys Asn Ser Ser Tyr Phe Val Glu Trp Ile
                 335                 340                 345

 Pro Asn Asn Val Lys Thr Ala Val Cys Asp Ile Pro Pro Arg Gly
                 350                 355                 360

 Leu Lys Met Ser Ala Thr Phe Ile Gly Asn Ser Thr Ala Ile Gln
                 365                 370                 375

 Glu Leu Phe Lys Arg Ile Ser Glu Gln Phe Thr Ala Met Phe Arg
                 380                 385                 390

 Arg Lys Ala Phe Leu His Trp Tyr Thr Gly Glu Gly Met Asp Glu
                 395                 400                 405

 Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn Asp Leu Val Ser
                 410                 415                 420

 Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Glu Glu Glu Gly Glu
                 425                 430                 435

 Phe Glu Glu Glu Ala Glu Glu Glu Val Ala
                 440                 445

<210> 1885
<211> 3189
<212> DNA
<213> Homo sapien

<400> 1885
 tttccagcca tggctgccat tacctgacca gcgccacagc cggtctctct 50

 gcaggcgccg ggagaagtga ccagagcaat ttctgctttt cacagggcgg 100

 gtttctcaac ggtgacttgt gggcagtgcc ttctgctgag cgagtcatgg 150

 cccgaaggca gaactaactg tgcctgcagt cttcactctc aggatgcagc 200

 cgaggtgggc ccaaggggcc acgatgtggc ttggagtcct gctgaccctt 250

 ctgctctgtt caagccttga gggtcaagaa aactctttca caatcaacag 300

 tgttgacatg aagagcctgc cggactggac ggtgcaaaat gggaagaacc 350

 tgaccctgca gtgcttcgcg gatgtcagca ccacctctca cgtcaagcct 400

 cagcaccaga tgctgttcta taaggatgac gtgctgtttt acaacatctc 450

 ctccatgaag agcacagaga gttattttat tcctgaagtc cggatctatg 500

 actcagggac atataaatgt actgtgattg tgaacaacaa agagaaaacc 550

 actgcagagt accaggtgtt ggtggaagga gtgcccagtc ccagggtgac 600

 actggacaag aaagaggcca tccaaggtgg gatcgtgagg gtcaactgtt 650

 ctgtcccaga ggaaaaggcc ccaatacact tcacaattga aaaacttgaa 700

 ctaaatgaaa aaatggtcaa gctgaaaaga gagaagaatt ctcgagacca 750

 gaattttgtg atactggaat tccccgttga ggaacaggac cgcgttttat 800

 ccttccgatg tcaagctagg atcatttctg ggatccatat gcagacctca 850

 gaatctacca agagtgaact ggtcaccgtg acggaatcct tctctacacc 900

 caagttccac atcagcccca ccggaatgat catggaagga gctcagctcc 950

 acattaagtg caccattcaa gtgactcacc tggcccagga gtttccagaa 1000

 atcataattc agaaggacaa ggcgattgtg gcccacaaca gacatggcaa 1050

 caaggctgtg tactcagtca tggccatggt ggagcacagt ggcaactaca 1100

 cgtgcaaagt ggagtccagc cgcatatcca aggtcagcag catcgtggtc 1150

 aacataacag aactattttc caagcccgaa ctggaatctt ccttcacaca 1200

 tctggaccaa ggtgaaagac tgaacctgtc ctgctccatc ccaggagcac 1250

 ctccagccaa cttcaccatc cagaaggaag atacgattgt gtcacagact 1300

 caagatttca ccaagatagc ctcaaagtcg gacagtggga cgtatatctg 1350

 cactgcaggt attgacaaag tggtcaagaa aagcaacaca gtccagatag 1400

 tcgtatgtga aatgctctcc cagcccagga tttcttatga tgcccagttt 1450

 gaggtcataa aaggacagac catcgaagtc cgttgcgaat cgatcagtgg 1500

 aactttgcct atttcttacc aacttttaaa aacaagtaaa gttttggaga 1550

 atagtaccaa gaactcaaat gatcctgcgg tattcaaaga caaccccact 1600

 gaagacgtcg aataccagtg tgttgcagat aattgccatt cccacgccaa 1650

 aatgttaagt gaggttctga gggtgaaggt gatagccccg gtggatgagg 1700

 tccagatttc tatcctgtca agtaaggtgg tggagtctgg agaggacatt 1750

 gtgctgcaat gtgctgtgaa tgaaggatct ggtcccatca cctataagtt 1800

 ttacagagaa aaagagggca aacccttcta tcaaatgacc tcaaatgcca 1850

 cccaggcatt ttggaccaag cagaaggcta acaaggaaca ggagggagag 1900

 tattactgca cagccttcaa cagagccaac cacgcctcca gtgtccccag 1950

 aagcaaaata ctgacagtca gagtcattct tgccccatgg aagaaaggac 2000

 ttattgcagt ggttatcatc ggagtgatca ttgctctctt gatcattgcg 2050

 gccaaatgtt attttctgag gaaagccaag gccaagcaga tgccagtgga 2100

 aatgtccagg ccagcagtac cacttctgaa ctccaacaac gagaaaatgt 2150

 cagatcccaa tatggaagct aacagtcatt acggtcacaa tgacgatgtc 2200

 ggaaaccatg caatgaaacc aataaatgat aataaagagc ctctgaactc 2250

 agacgtgcag tacacggaag ttcaagtgtc ctcagctgag tctcacaaag 2300

 atctaggaaa gaaggacaca gagacagtgt acagtgaagt ccggaaagct 2350

 gtccctgatg ccgtggaaag cagatactct agaacggaag gctcccttga 2400

 tggaacttag acagcaaggc cagatgcaca tccctggaag gacatccatg 2450

 ttccgagaag aacagatgat ccctgtattt caagacctct gtgcacttat 2500

 ttatgaacct gccctgctcc cacagaacac agcaattcct caggctaagc 2550

 tgccggttct taaatccatc ctgctaagtt aatgttgggt agaaagagat 2600

 acagaggggc tgttgaattt cccacataca ctccttccac caagttggaa 2650

 catccttgga aattggaaga gcacaagagg agatccaggg caaggccatt 2700

 gggatattct gaaacttgaa tattttgttt tgtgcagaga taaagacctt 2750

 ttccatgcac cctcatacac agaaaccaat tttctttttt atactcaatc 2800

 atttctagcg catggcctgg ttagaggctg gttttttctc ttttcctttg 2850

 gtccttcaaa ggcttgtagt tttgggtagt ccttgttctt tggaaataca 2900

 cagtgctgac cagacagcct ccccctgtcc cctctatgac ctcgccctcc 2950

 acaaatggga aaaccagact acttgggagc accgcctgtg aaataccaac 3000

 ctgaagacac ggttcattca ggcaacgcac aaaacagaaa atgaaggtgg 3050

 aacaagcaca gatgttcttc aactgttttt gtctacactc tttctctttt 3100

 cctctaccat gctgaaggct gaaagacagg aagatggtgc catcagcaaa 3150

 tattattctt aattgaaaac ttgaaaaaaa aaaaaaaaa 3189

<210> 1886
<211> 738
<212> PRT
<213> Homo sapien

<400> 1886
 Met Gln Pro Arg Trp Ala Gln Gly Ala Thr Met Trp Leu Gly Val
   1               5                  10                  15

 Leu Leu Thr Leu Leu Leu Cys Ser Ser Leu Glu Gly Gln Glu Asn
                  20                  25                  30

 Ser Phe Thr Ile Asn Ser Val Asp Met Lys Ser Leu Pro Asp Trp
                  35                  40                  45

 Thr Val Gln Asn Gly Lys Asn Leu Thr Leu Gln Cys Phe Ala Asp
                  50                  55                  60

 Val Ser Thr Thr Ser His Val Lys Pro Gln His Gln Met Leu Phe
                  65                  70                  75

 Tyr Lys Asp Asp Val Leu Phe Tyr Asn Ile Ser Ser Met Lys Ser
                  80                  85                  90

 Thr Glu Ser Tyr Phe Ile Pro Glu Val Arg Ile Tyr Asp Ser Gly
                  95                 100                 105

 Thr Tyr Lys Cys Thr Val Ile Val Asn Asn Lys Glu Lys Thr Thr
                 110                 115                 120

 Ala Glu Tyr Gln Val Leu Val Glu Gly Val Pro Ser Pro Arg Val
                 125                 130                 135

 Thr Leu Asp Lys Lys Glu Ala Ile Gln Gly Gly Ile Val Arg Val
                 140                 145                 150

 Asn Cys Ser Val Pro Glu Glu Lys Ala Pro Ile His Phe Thr Ile
                 155                 160                 165

 Glu Lys Leu Glu Leu Asn Glu Lys Met Val Lys Leu Lys Arg Glu
                 170                 175                 180

 Lys Asn Ser Arg Asp Gln Asn Phe Val Ile Leu Glu Phe Pro Val
                 185                 190                 195

 Glu Glu Gln Asp Arg Val Leu Ser Phe Arg Cys Gln Ala Arg Ile
                 200                 205                 210

 Ile Ser Gly Ile His Met Gln Thr Ser Glu Ser Thr Lys Ser Glu
                 215                 220                 225

 Leu Val Thr Val Thr Glu Ser Phe Ser Thr Pro Lys Phe His Ile
                 230                 235                 240

 Ser Pro Thr Gly Met Ile Met Glu Gly Ala Gln Leu His Ile Lys
                 245                 250                 255

 Cys Thr Ile Gln Val Thr His Leu Ala Gln Glu Phe Pro Glu Ile
                 260                 265                 270

 Ile Ile Gln Lys Asp Lys Ala Ile Val Ala His Asn Arg His Gly
                 275                 280                 285

 Asn Lys Ala Val Tyr Ser Val Met Ala Met Val Glu His Ser Gly
                 290                 295                 300

 Asn Tyr Thr Cys Lys Val Glu Ser Ser Arg Ile Ser Lys Val Ser
                 305                 310                 315

 Ser Ile Val Val Asn Ile Thr Glu Leu Phe Ser Lys Pro Glu Leu
                 320                 325                 330

 Glu Ser Ser Phe Thr His Leu Asp Gln Gly Glu Arg Leu Asn Leu
                 335                 340                 345

 Ser Cys Ser Ile Pro Gly Ala Pro Pro Ala Asn Phe Thr Ile Gln
                 350                 355                 360

 Lys Glu Asp Thr Ile Val Ser Gln Thr Gln Asp Phe Thr Lys Ile
                 365                 370                 375

 Ala Ser Lys Ser Asp Ser Gly Thr Tyr Ile Cys Thr Ala Gly Ile
                 380                 385                 390

 Asp Lys Val Val Lys Lys Ser Asn Thr Val Gln Ile Val Val Cys
                 395                 400                 405

 Glu Met Leu Ser Gln Pro Arg Ile Ser Tyr Asp Ala Gln Phe Glu
                 410                 415                 420

 Val Ile Lys Gly Gln Thr Ile Glu Val Arg Cys Glu Ser Ile Ser
                 425                 430                 435

 Gly Thr Leu Pro Ile Ser Tyr Gln Leu Leu Lys Thr Ser Lys Val
                 440                 445                 450

 Leu Glu Asn Ser Thr Lys Asn Ser Asn Asp Pro Ala Val Phe Lys
                 455                 460                 465

 Asp Asn Pro Thr Glu Asp Val Glu Tyr Gln Cys Val Ala Asp Asn
                 470                 475                 480

 Cys His Ser His Ala Lys Met Leu Ser Glu Val Leu Arg Val Lys
                 485                 490                 495

 Val Ile Ala Pro Val Asp Glu Val Gln Ile Ser Ile Leu Ser Ser
                 500                 505                 510

 Lys Val Val Glu Ser Gly Glu Asp Ile Val Leu Gln Cys Ala Val
                 515                 520                 525

 Asn Glu Gly Ser Gly Pro Ile Thr Tyr Lys Phe Tyr Arg Glu Lys
                 530                 535                 540

 Glu Gly Lys Pro Phe Tyr Gln Met Thr Ser Asn Ala Thr Gln Ala
                 545                 550                 555

 Phe Trp Thr Lys Gln Lys Ala Asn Lys Glu Gln Glu Gly Glu Tyr
                 560                 565                 570

 Tyr Cys Thr Ala Phe Asn Arg Ala Asn His Ala Ser Ser Val Pro
                 575                 580                 585

 Arg Ser Lys Ile Leu Thr Val Arg Val Ile Leu Ala Pro Trp Lys
                 590                 595                 600

 Lys Gly Leu Ile Ala Val Val Ile Ile Gly Val Ile Ile Ala Leu
                 605                 610                 615

 Leu Ile Ile Ala Ala Lys Cys Tyr Phe Leu Arg Lys Ala Lys Ala
                 620                 625                 630

 Lys Gln Met Pro Val Glu Met Ser Arg Pro Ala Val Pro Leu Leu
                 635                 640                 645

 Asn Ser Asn Asn Glu Lys Met Ser Asp Pro Asn Met Glu Ala Asn
                 650                 655                 660

 Ser His Tyr Gly His Asn Asp Asp Val Gly Asn His Ala Met Lys
                 665                 670                 675

 Pro Ile Asn Asp Asn Lys Glu Pro Leu Asn Ser Asp Val Gln Tyr
                 680                 685                 690

 Thr Glu Val Gln Val Ser Ser Ala Glu Ser His Lys Asp Leu Gly
                 695                 700                 705

 Lys Lys Asp Thr Glu Thr Val Tyr Ser Glu Val Arg Lys Ala Val
                 710                 715                 720

 Pro Asp Ala Val Glu Ser Arg Tyr Ser Arg Thr Glu Gly Ser Leu
                 725                 730                 735

 Asp Gly Thr


<210> 1887
<211> 2228
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 230-320, 1706-1820
<223> Unknown base

<400> 1887
 atctcacgtt agctagagac agaactggag ctagcagtca gatctcttac 50

 aaagttgcct ttcttcttct gtgggtaagt ggggcaccct tgggacgctg 100

 tgctgggcgt acatgggtgc ttgatgaagt tacttggtgg actgatgtga 150

 ttgatgtcca acatgtatgc agggacagag gctatggtcc ctacagagca 200

 ggcatggaga gaaggagaaa tacatacggn nnnnnnnnnn nnnnnnnnnn 250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300

 nnnnnnnnnn nnnnnnnnnn ttgcttgcta aagaagtggt ctcctgaggt 350

 cttaagacgt tcctgacaat gtcttgagtg ggtgggagag aggctgcagt 400

 cattgtgctg tggaatttca gaggtgagaa ccacacctaa ccaaaattac 450

 tttccctgtt tgcctcagtg acacagctgc aggaaccctg gtgggtgttg 500

 tattaagtaa atttgacctt tattctttgc agatctgtga aatgttgtct 550

 tctgaggggc cacgtgtatc tgtagtgctg aggactcctt gggcctctga 600

 agtcacagag agaaccctgc agggtggggg accagtgtgt gacagccctg 650

 ctttgcattt tctttgagaa gtgctgtcat tttgcatttc tctccaccag 700

 ggcaatcttc aatcttgaga ggtgtgatca taacttgcct tgtttcttgt 750

 cgctacagag aacggaaggc tcccttgatg gaacttagac agcaaggcca 800

 gatgcacatc cctggaagga catccatgtt ccgagaagaa cagatgatcc 850

 ctgtatttca agacctctgt gcacttattt atgaacctgc cctgctccca 900

 cagaacacag caattcctca ggctaagctg ccggttctta aatccatcct 950

 gctaagttaa tgttgggtag aaagagatac agaggggctg ttgaatttcc 1000

 cacataccct ccttccacca agttggaaca tccttggaaa ttggaagagc 1050

 acaagaggag atccagggca aggccattgg gatattctga aacttgaata 1100

 ttttgttttg tgcagagata aagacctttt ccatgcaccc tcatacacag 1150

 aaaccaattt tcttttttat actcaatcat ttctagcgca tggcctggtt 1200

 agaggctggt tttttctctt ttcctttggt ccttcaaagg cttgtagttt 1250

 tgggtagtcc ttgttctttg gaaatacaca gtgctgacca gacagcctcc 1300

 ccctgtcccc tctatgacct cgccctccac aaatgggaaa accagactac 1350

 ttgggagcac cgcctgtgaa ataccaacct gaagacaccg ttcattcagg 1400

 caacgcacaa aacagaaaat gaaggtggaa caagcacaga tgttcttcaa 1450

 ctgtttttgt ctacactctt tctcttttcc tctaccatgc tgaaggctga 1500

 aagacaggaa gatggtgcca tcagcaaata ttattcttaa ttgaaaactt 1550

 gaaatgtgta tgtttcttac taatttttaa aaatgtattc cttgccaggc 1600

 ctagacaagg atcgctcacg cctgtatatc ccagcacttc aggtagagct 1650

 gaggtgggcg gtatcgacct gaggtcaggt agctttgaga ccagcctgat 1700

 gaaacnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1800

 nnnnnnnnnn nnnnnnnnnn taggttgtag tgtagcggac ctcgcgccac 1850

 tggcactcct agctctgagt gactagagtg agaatccatc tcaaaaaaac 1900

 aaataaacaa aattgcttgc taaagaagtg gtctcctgag gtcttaagac 1950

 attcctgaca gtgtcttgag tgggtgggag agaggctgct gtcattgcgc 2000

 tgtggaattt cacagatgag aaccacgcct agccaaaatc acttttcctg 2050

 tttgcctcag tgacacagct gcagggaccc tcgtggatgt tgtattaaat 2100

 aaatttgacc tttgctcttt gcagatctgt gaaatgttgt cttctgaggg 2150

 gccacatgca tctatagtgc tgaggactcc ttgggcctct gaagtcacag 2200

 agagaaccga gcaggtctat gtttttgt 2228

<210> 1888
<211> 114
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 77-106
<223> unknown amino acid

<220>
<221> Unsure
<222> 230-320, 1706-1820
<223> Unknown amino acid

<400> 1888
 Leu Thr Leu Ala Arg Asp Arg Thr Gly Ala Ser Ser Gln Ile Ser
   1               5                  10                  15

 Tyr Lys Val Ala Phe Leu Leu Leu Trp Val Ser Gly Ala Pro Leu
                  20                  25                  30

 Gly Arg Cys Ala Gly Arg Thr Trp Val Leu Asp Glu Val Thr Trp
                  35                  40                  45

 Trp Thr Asp Val Ile Asp Val Gln His Val Cys Arg Asp Arg Gly
                  50                  55                  60

 Tyr Gly Pro Tyr Arg Ala Gly Met Glu Arg Arg Arg Asn Thr Tyr
                  65                  70                  75

 Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Leu Leu Ala Lys Glu Val Val Ser
                 110

<210> 1889
<211> 3189
<212> DNA
<213> Homo sapien

<400> 1889
 tttccagcca tggctgccat tacctgacca gcgccacagc cggtctctct 50

 gcaggcgccg ggagaagtga ccagagcaat ttctgctttt cacagggcgg 100

 gtttctcaac ggtgacttgt gggcagtgcc ttctgctgag cgagtcatgg 150

 cccgaaggca gaactaactg tgcctgcagt cttcactctc aggatgcagc 200

 cgaggtgggc ccaaggggcc acgatgtggc ttggagtcct gctgaccctt 250

 ctgctctgtt caagccttga gggtcaagaa aactctttca caatcaacag 300

 tgttgacatg aagagcctgc cggactggac ggtgcaaaat gggaagaacc 350

 tgaccctgca gtgcttcgcg gatgtcagca ccacctctca cgtcaagcct 400

 cagcaccaga tgctgttcta taaggatgac gtgctgtttt acaacatctc 450

 ctccatgaag agcacagaga gttattttat tcctgaagtc cggatctatg 500

 actcagggac atataaatgt actgtgattg tgaacaacaa agagaaaacc 550

 actgcagagt accaggtgtt ggtggaagga gtgcccagtc ccagggtgac 600

 actggacaag aaagaggcca tccaaggtgg gatcgtgagg gtcaactgtt 650

 ctgtcccaga ggaaaaggcc ccaatacact tcacaattga aaaacttgaa 700

 ctaaatgaaa aaatggtcaa gctgaaaaga gagaagaatt ctcgagacca 750

 gaattttgtg atactggaat tccccgttga ggaacaggac cgcgttttat 800

 ccttccgatg tcaagctagg atcatttctg ggatccatat gcagacctca 850

 gaatctacca agagtgaact ggtcaccgtg acggaatcct tctctacacc 900

 caagttccac atcagcccca ccggaatgat catggaagga gctcagctcc 950

 acattaagtg caccattcaa gtgactcacc tggcccagga gtttccagaa 1000

 atcataattc agaaggacaa ggcgattgtg gcccacaaca gacatggcaa 1050

 caaggctgtg tactcagtca tggccatggt ggagcacagt ggcaactaca 1100

 cgtgcaaagt ggagtccagc cgcatatcca aggtcagcag catcgtggtc 1150

 aacataacag aactattttc caagcccgaa ctggaatctt ccttcacaca 1200

 tctggaccaa ggtgaaagac tgaacctgtc ctgctccatc ccaggagcac 1250

 ctccagccaa cttcaccatc cagaaggaag atacgattgt gtcacagact 1300

 caagatttca ccaagatagc ctcaaagtcg gacagtggga cgtatatctg 1350

 cactgcaggt attgacaaag tggtcaagaa aagcaacaca gtccagatag 1400

 tcgtatgtga aatgctctcc cagcccagga tttcttatga tgcccagttt 1450

 gaggtcataa aaggacagac catcgaagtc cgttgcgaat cgatcagtgg 1500

 aactttgcct atttcttacc aacttttaaa aacaagtaaa gttttggaga 1550

 atagtaccaa gaactcaaat gatcctgcgg tattcaaaga caaccccact 1600

 gaagacgtcg aataccagtg tgttgcagat aattgccatt cccacgccaa 1650

 aatgttaagt gaggttctga gggtgaaggt gatagccccg gtggatgagg 1700

 tccagatttc tatcctgtca agtaaggtgg tggagtctgg agaggacatt 1750

 gtgctgcaat gtgctgtgaa tgaaggatct ggtcccatca cctataagtt 1800

 ttacagagaa aaagagggca aacccttcta tcaaatgacc tcaaatgcca 1850

 cccaggcatt ttggaccaag cagaaggcta acaaggaaca ggagggagag 1900

 tattactgca cagccttcaa cagagccaac cacgcctcca gtgtccccag 1950

 aagcaaaata ctgacagtca gagtcattct tgccccatgg aagaaaggac 2000

 ttattgcagt ggttatcatc ggagtgatca ttgctctctt gatcattgcg 2050

 gccaaatgtt attttctgag gaaagccaag gccaagcaga tgccagtgga 2100

 aatgtccagg ccagcagtac cacttctgaa ctccaacaac gagaaaatgt 2150

 cagatcccaa tatggaagct aacagtcatt acggtcacaa tgacgatgtc 2200

 ggaaaccatg caatgaaacc aataaatgat aataaagagc ctctgaactc 2250

 agacgtgcag tacacggaag ttcaagtgtc ctcagctgag tctcacaaag 2300

 atctaggaaa gaaggacaca gagacagtgt acagtgaagt ccggaaagct 2350

 gtccctgatg ccgtggaaag cagatactct agaacggaag gctcccttga 2400

 tggaacttag acagcaaggc cagatgcaca tccctggaag gacatccatg 2450

 ttccgagaag aacagatgat ccctgtattt caagacctct gtgcacttat 2500

 ttatgaacct gccctgctcc cacagaacac agcaattcct caggctaagc 2550

 tgccggttct taaatccatc ctgctaagtt aatgttgggt agaaagagat 2600

 acagaggggc tgttgaattt cccacataca ctccttccac caagttggaa 2650

 catccttgga aattggaaga gcacaagagg agatccaggg caaggccatt 2700

 gggatattct gaaacttgaa tattttgttt tgtgcagaga taaagacctt 2750

 ttccatgcac cctcatacac agaaaccaat tttctttttt atactcaatc 2800

 atttctagcg catggcctgg ttagaggctg gttttttctc ttttcctttg 2850

 gtccttcaaa ggcttgtagt tttgggtagt ccttgttctt tggaaataca 2900

 cagtgctgac cagacagcct ccccctgtcc cctctatgac ctcgccctcc 2950

 acaaatggga aaaccagact acttgggagc accgcctgtg aaataccaac 3000

 ctgaagacac ggttcattca ggcaacgcac aaaacagaaa atgaaggtgg 3050

 aacaagcaca gatgttcttc aactgttttt gtctacactc tttctctttt 3100

 cctctaccat gctgaaggct gaaagacagg aagatggtgc catcagcaaa 3150

 tattattctt aattgaaaac ttgaaaaaaa aaaaaaaaa 3189

<210> 1890
<211> 738
<212> PRT
<213> Homo sapien

<400> 1890
 Met Gln Pro Arg Trp Ala Gln Gly Ala Thr Met Trp Leu Gly Val
   1               5                  10                  15

 Leu Leu Thr Leu Leu Leu Cys Ser Ser Leu Glu Gly Gln Glu Asn
                  20                  25                  30

 Ser Phe Thr Ile Asn Ser Val Asp Met Lys Ser Leu Pro Asp Trp
                  35                  40                  45

 Thr Val Gln Asn Gly Lys Asn Leu Thr Leu Gln Cys Phe Ala Asp
                  50                  55                  60

 Val Ser Thr Thr Ser His Val Lys Pro Gln His Gln Met Leu Phe
                  65                  70                  75

 Tyr Lys Asp Asp Val Leu Phe Tyr Asn Ile Ser Ser Met Lys Ser
                  80                  85                  90

 Thr Glu Ser Tyr Phe Ile Pro Glu Val Arg Ile Tyr Asp Ser Gly
                  95                 100                 105

 Thr Tyr Lys Cys Thr Val Ile Val Asn Asn Lys Glu Lys Thr Thr
                 110                 115                 120

 Ala Glu Tyr Gln Val Leu Val Glu Gly Val Pro Ser Pro Arg Val
                 125                 130                 135

 Thr Leu Asp Lys Lys Glu Ala Ile Gln Gly Gly Ile Val Arg Val
                 140                 145                 150

 Asn Cys Ser Val Pro Glu Glu Lys Ala Pro Ile His Phe Thr Ile
                 155                 160                 165

 Glu Lys Leu Glu Leu Asn Glu Lys Met Val Lys Leu Lys Arg Glu
                 170                 175                 180

 Lys Asn Ser Arg Asp Gln Asn Phe Val Ile Leu Glu Phe Pro Val
                 185                 190                 195

 Glu Glu Gln Asp Arg Val Leu Ser Phe Arg Cys Gln Ala Arg Ile
                 200                 205                 210

 Ile Ser Gly Ile His Met Gln Thr Ser Glu Ser Thr Lys Ser Glu
                 215                 220                 225

 Leu Val Thr Val Thr Glu Ser Phe Ser Thr Pro Lys Phe His Ile
                 230                 235                 240

 Ser Pro Thr Gly Met Ile Met Glu Gly Ala Gln Leu His Ile Lys
                 245                 250                 255

 Cys Thr Ile Gln Val Thr His Leu Ala Gln Glu Phe Pro Glu Ile
                 260                 265                 270

 Ile Ile Gln Lys Asp Lys Ala Ile Val Ala His Asn Arg His Gly
                 275                 280                 285

 Asn Lys Ala Val Tyr Ser Val Met Ala Met Val Glu His Ser Gly
                 290                 295                 300

 Asn Tyr Thr Cys Lys Val Glu Ser Ser Arg Ile Ser Lys Val Ser
                 305                 310                 315

 Ser Ile Val Val Asn Ile Thr Glu Leu Phe Ser Lys Pro Glu Leu
                 320                 325                 330

 Glu Ser Ser Phe Thr His Leu Asp Gln Gly Glu Arg Leu Asn Leu
                 335                 340                 345

 Ser Cys Ser Ile Pro Gly Ala Pro Pro Ala Asn Phe Thr Ile Gln
                 350                 355                 360

 Lys Glu Asp Thr Ile Val Ser Gln Thr Gln Asp Phe Thr Lys Ile
                 365                 370                 375

 Ala Ser Lys Ser Asp Ser Gly Thr Tyr Ile Cys Thr Ala Gly Ile
                 380                 385                 390

 Asp Lys Val Val Lys Lys Ser Asn Thr Val Gln Ile Val Val Cys
                 395                 400                 405

 Glu Met Leu Ser Gln Pro Arg Ile Ser Tyr Asp Ala Gln Phe Glu
                 410                 415                 420

 Val Ile Lys Gly Gln Thr Ile Glu Val Arg Cys Glu Ser Ile Ser
                 425                 430                 435

 Gly Thr Leu Pro Ile Ser Tyr Gln Leu Leu Lys Thr Ser Lys Val
                 440                 445                 450

 Leu Glu Asn Ser Thr Lys Asn Ser Asn Asp Pro Ala Val Phe Lys
                 455                 460                 465

 Asp Asn Pro Thr Glu Asp Val Glu Tyr Gln Cys Val Ala Asp Asn
                 470                 475                 480

 Cys His Ser His Ala Lys Met Leu Ser Glu Val Leu Arg Val Lys
                 485                 490                 495

 Val Ile Ala Pro Val Asp Glu Val Gln Ile Ser Ile Leu Ser Ser
                 500                 505                 510

 Lys Val Val Glu Ser Gly Glu Asp Ile Val Leu Gln Cys Ala Val
                 515                 520                 525

 Asn Glu Gly Ser Gly Pro Ile Thr Tyr Lys Phe Tyr Arg Glu Lys
                 530                 535                 540

 Glu Gly Lys Pro Phe Tyr Gln Met Thr Ser Asn Ala Thr Gln Ala
                 545                 550                 555

 Phe Trp Thr Lys Gln Lys Ala Asn Lys Glu Gln Glu Gly Glu Tyr
                 560                 565                 570

 Tyr Cys Thr Ala Phe Asn Arg Ala Asn His Ala Ser Ser Val Pro
                 575                 580                 585

 Arg Ser Lys Ile Leu Thr Val Arg Val Ile Leu Ala Pro Trp Lys
                 590                 595                 600

 Lys Gly Leu Ile Ala Val Val Ile Ile Gly Val Ile Ile Ala Leu
                 605                 610                 615

 Leu Ile Ile Ala Ala Lys Cys Tyr Phe Leu Arg Lys Ala Lys Ala
                 620                 625                 630

 Lys Gln Met Pro Val Glu Met Ser Arg Pro Ala Val Pro Leu Leu
                 635                 640                 645

 Asn Ser Asn Asn Glu Lys Met Ser Asp Pro Asn Met Glu Ala Asn
                 650                 655                 660

 Ser His Tyr Gly His Asn Asp Asp Val Gly Asn His Ala Met Lys
                 665                 670                 675

 Pro Ile Asn Asp Asn Lys Glu Pro Leu Asn Ser Asp Val Gln Tyr
                 680                 685                 690

 Thr Glu Val Gln Val Ser Ser Ala Glu Ser His Lys Asp Leu Gly
                 695                 700                 705

 Lys Lys Asp Thr Glu Thr Val Tyr Ser Glu Val Arg Lys Ala Val
                 710                 715                 720

 Pro Asp Ala Val Glu Ser Arg Tyr Ser Arg Thr Glu Gly Ser Leu
                 725                 730                 735

 Asp Gly Thr


<210> 1891
<211> 2443
<212> DNA
<213> Homo sapien

<400> 1891
 ctccgccgtg ctaactcctc gctagctctc cctctcacac acgctcacac 50

 ccggctcgag atggcggcgg cggcggcggc ggcgggggac tcggactcct 100

 gggacgccga cgctttctcc gtggaagacc cagtgcggaa ggtggggggc 150

 ggcggcactg ccggcgggga ccgctgggga ggcgaggacg aggacgagga 200

 cgtcaaggat aactgggatg acgatgatga tgaaaaaaaa gaggaagcag 250

 aagtaaaacc agaggtaaaa atttcagaaa agaaaaaaat agcagagaag 300

 ataaaagaga aagaacggca acagaagaaa aggcaagaag aaattaaaaa 350

 gaggttagaa gaacccgaag aacctaaagt gctaacacca gaagaacaat 400

 tagcagataa actgcggcta aagaaattac aggaagagtc agacctcgaa 450

 ttagcaaagg aaacttttgg tgttaataat gcagtttatg gaatagatgc 500

 tatgaaccca tcttcaagag atgactttac agagtttgga aagttactaa 550

 aagataaaat tacacaatat gaaaagtcac tatattatgc cagttttttg 600

 gaagtcttag ttcgagatgt gtgtatttca ttggaaattg atgacttgaa 650

 aaaaattacc aattcactga ctgtgctttg cagtgaaaaa cagaagcaag 700

 aaaagcaaag caaagccaaa aagaagaaga aaggtgtggt tcctggaggg 750

 ggattaaaag ccaccatgaa agatgatctg gcagattatg gtggttatga 800

 tggaggatat gtacaagact atgaagactt catgtgacat tttatctttt 850

 cttggtgtca tctttatgtt gcccacaatc ccttgaacat gtagcacaac 900

 ttcctttcct ttcagttctg ccaaatgcta caatcagaag tgcagtatct 950

 tttgtgctgg ttaaaattgg gaacctaagt tgctactaaa tcatagttca 1000

 aaacctaata atgttgtcgt tgttgctatc tgatttcata gcagcagtca 1050

 ctaaattgga aacaaaaggt tgcaacgtga caaaaaaaat tgtgtagtat 1100

 ttaccagcac cattcagtaa tacagcctta accatacctc cttgaactac 1150

 ttcataactt gtcaagaaaa gcagtttgca gcaagggcat gtggtgtgca 1200

 cctagtatta aaattgcttt gtcttaaaat tgaacatgag gatattaaaa 1250

 atacattgtg aagaatactg cttatctcag agtgaagata ctgcggctga 1300

 aaagcactag tttgatataa aattaaaatg accaaaaccc tccaactttg 1350

 aagctaaaga aggtaaacct ttccattatt gcattacatg ttgtggaatc 1400

 tctcgagtgc aaagactgtc tagttattta tcaggctatt tctactgatg 1450

 aactgcttca ggtgggggag ggaaacttat ttttatttgc ctgatttaag 1500

 tgtctgagaa acaaatcttt gttctcttag gctgcaatgg aacaacttta 1550

 ccagggtttt ggcatttcct ttcctttcct ttataaaaca tgctcagcaa 1600

 actgcaccag ttaactacag tttggtaaat tgttatgtta acaattatga 1650

 catctgcaat gttttataaa gcaactaatt taataaaatc actgttgtga 1700

 ggacttaaat tttgtgttac ctcccaatat atactttttg agagtataga 1750

 acacagctct tgggagtaca gttctctacg ttctctacta aatcttaata 1800

 aatgcttgga catagttaca gctttaaaac atgagtgatt tgccaggtcc 1850

 ttatgttgtc accatagagc aacaaaggta tagggctgcc ttcctcttat 1900

 ttatttgggg acattatttt gttatttaga taccaaggcc taattaatta 1950

 agtacctata agaactattt atttggagta actgagcctg taactcaggt 2000

 ttatggctgt taagtataga ttggggaatc tttattatgt cttctcctaa 2050

 gcagtttaac caaatgtgtg gttagtgttt ttttattccc ctaagacaga 2100

 aagaacaaaa aatgttttaa atttctctta tataggaaat aataggaacg 2150

 tcaaagctct gtatacctac taagtggaaa acaagaccat catctaagtg 2200

 atttgagaaa ttaacaaaag tagtgactac acagcaataa ttacagtaaa 2250

 ttaaataaag attcctttaa ggcagacaag ggctaagatt tccttagcag 2300

 taataatgac atacactgaa ttgaaaatct attttattac agaaagatca 2350

 gtttctaaca aatgaaaatg tatcacctgt tccttaactg tgtaaataat 2400

 aattaaattt ctttgaaact ggaaaaaaaa aaaaaaaaaa aaa 2443

<210> 1892
<211> 258
<212> PRT
<213> Homo sapien

<400> 1892
 Met Ala Ala Ala Ala Ala Ala Ala Gly Asp Ser Asp Ser Trp Asp
   1               5                  10                  15

 Ala Asp Ala Phe Ser Val Glu Asp Pro Val Arg Lys Val Gly Gly
                  20                  25                  30

 Gly Gly Thr Ala Gly Gly Asp Arg Trp Gly Gly Glu Asp Glu Asp
                  35                  40                  45

 Glu Asp Val Lys Asp Asn Trp Asp Asp Asp Asp Asp Glu Lys Lys
                  50                  55                  60

 Glu Glu Ala Glu Val Lys Pro Glu Val Lys Ile Ser Glu Lys Lys
                  65                  70                  75

 Lys Ile Ala Glu Lys Ile Lys Glu Lys Glu Arg Gln Gln Lys Lys
                  80                  85                  90

 Arg Gln Glu Glu Ile Lys Lys Arg Leu Glu Glu Pro Glu Glu Pro
                  95                 100                 105

 Lys Val Leu Thr Pro Glu Glu Gln Leu Ala Asp Lys Leu Arg Leu
                 110                 115                 120

 Lys Lys Leu Gln Glu Glu Ser Asp Leu Glu Leu Ala Lys Glu Thr
                 125                 130                 135

 Phe Gly Val Asn Asn Ala Val Tyr Gly Ile Asp Ala Met Asn Pro
                 140                 145                 150

 Ser Ser Arg Asp Asp Phe Thr Glu Phe Gly Lys Leu Leu Lys Asp
                 155                 160                 165

 Lys Ile Thr Gln Tyr Glu Lys Ser Leu Tyr Tyr Ala Ser Phe Leu
                 170                 175                 180

 Glu Val Leu Val Arg Asp Val Cys Ile Ser Leu Glu Ile Asp Asp
                 185                 190                 195

 Leu Lys Lys Ile Thr Asn Ser Leu Thr Val Leu Cys Ser Glu Lys
                 200                 205                 210

 Gln Lys Gln Glu Lys Gln Ser Lys Ala Lys Lys Lys Lys Lys Gly
                 215                 220                 225

 Val Val Pro Gly Gly Gly Leu Lys Ala Thr Met Lys Asp Asp Leu
                 230                 235                 240

 Ala Asp Tyr Gly Gly Tyr Asp Gly Gly Tyr Val Gln Asp Tyr Glu
                 245                 250                 255

 Asp Phe Met


<210> 1893
<211> 3455
<212> DNA
<213> Homo sapien

<400> 1893
 ggtttccgga gctgcggcgg cgcagactgg gagggggagc cgggggttcc 50

 gacgtcgcag ccgagggaac aagccccaac cggatcctgg acaggcaccc 100

 cggcttggcg ctgtctctcc ccctcggctc ggagaggccc ttcggcctga 150

 gggagcctcg ccgcccgtcc ccggcacacg cgcagccccg gcctctcggc 200

 ctctgccgga gaaacagttg ggacccctga ttttagcagg atggcccaat 250

 ggaatcagct acagcagctt gacacacggt acctggagca gctccatcag 300

 ctctacagtg acagcttccc aatggagctg cggcagtttc tggccccttg 350

 gattgagagt caagattggg catatgcggc cagcaaagaa tcacatgcca 400

 ctttggtgtt tcataatctc ctgggagaga ttgaccagca gtatagccgc 450

 ttcctgcaag agtcgaatgt tctctatcag cacaatctac gaagaatcaa 500

 gcagtttctt cagagcaggt atcttgagaa gccaatggag attgcccgga 550

 ttgtggcccg gtgcctgtgg gaagaatcac gccttctaca gactgcagcc 600

 actgcggccc agcaaggggg ccaggccaac caccccacag cagccgtggt 650

 gacggagaag cagcagatgc tggagcagca ccttcaggat gtccggaaga 700

 gagtgcagga tctagaacag aaaatgaaag tggtagagaa tctccaggat 750

 gactttgatt tcaactataa aaccctcaag agtcaaggag acatgcaaga 800

 tctgaatgga aacaaccagt cagtgaccag gcagaagatg cagcagctgg 850

 aacagatgct cactgcgctg gaccagatgc ggagaagcat cgtgagtgag 900

 ctggcggggc ttttgtcagc gatggagtac gtgcagaaaa ctctcacgga 950

 cgaggagctg gctgactgga agaggcggca acagattgcc tgcattggag 1000

 gcccgcccaa catctgccta gatcggctag aaaactggat aacgtcatta 1050

 gcagaatctc aacttcagac ccgtcaacaa attaagaaac tggaggagtt 1100

 gcagcaaaaa gtttcctaca aaggggaccc cattgtacag caccggccga 1150

 tgctggagga gagaatcgtg gagctgttta gaaacttaat gaaaagtgcc 1200

 tttgtggtgg agcggcagcc ctgcatgccc atgcatcctg accggcccct 1250

 cgtcatcaag accggcgtcc agttcactac taaagtcagg ttgctggtca 1300

 aattccctga gttgaattat cagcttaaaa ttaaagtgtg cattgacaaa 1350

 gactctgggg acgttgcagc tctcagagga tcccggaaat ttaacattct 1400

 gggcacaaac acaaaagtga tgaacatgga agaatccaac aacggcagcc 1450

 tctctgcaga attcaaacac ttgaccctga gggagcagag atgtgggaat 1500

 gggggccgag ccaattgtga tgcttccctg attgtgactg aggagctgca 1550

 cctgatcacc tttgagaccg aggtgtatca ccaaggcctc aagattgacc 1600

 tagagaccca ctccttgcca gttgtggtga tctccaacat ctgtcagatg 1650

 ccaaatgcct gggcgtccat cctgtggtac aacatgctga ccaacaatcc 1700

 caagaatgta aactttttta ccaagccccc aattggaacc tgggatcaag 1750

 tggccgaggt cctgagctgg cagttctcct ccaccaccaa gcgaggactg 1800

 agcatcgagc agctgactac actggcagag aaactcttgg gacctggtgt 1850

 gaattattca gggtgtcaga tcacatgggc taaattttgc aaagaaaaca 1900

 tggctggcaa gggcttctcc ttctgggtct ggctggacaa tatcattgac 1950

 cttgtgaaaa agtacatcct ggccctttgg aacgaagggt acatcatggg 2000

 ctttatcagt aaggagcggg agcgggccat cttgagcact aagcctccag 2050

 gcaccttcct gctaagattc agtgaaagca gcaaagaagg aggcgtcact 2100

 ttcacttggg tggagaagga catcagcggt aagacccaga tccagtccgt 2150

 ggaaccatac acaaagcagc agctgaacaa catgtcattt gctgaaatca 2200

 tcatgggcta taagatcatg gatgctacca atatcctggt gtctccactg 2250

 gtctatctct atcctgacat tcccaaggag gaggcattcg gaaagtattg 2300

 tcggccagag agccaggagc atcctgaagc tgacccaggt agcgctgccc 2350

 catacctgaa gaccaagttt atctgtgtga caccaacgac ctgcagcaat 2400

 accattgacc tgccgatgtc cccccgcact ttagattcat tgatgcagtt 2450

 tggaaataat ggtgaaggtg ctgaaccctc agcaggaggg cagtttgagt 2500

 ccctcacctt tgacatggag ttgacctcgg agtgcgctac ctcccccatg 2550

 tgaggagctg agaacggaag ctgcagaaag atacgactga ggcgcctacc 2600

 tgcattctgc cacccctcac acagccaaac cccagatcat ctgaaactac 2650

 taactttgtg gttccagatt ttttttaatc tcctacttct gctatctttg 2700

 agcaatctgg gcacttttaa aaatagagaa atgagtgaat gtgggtgatc 2750

 tgcttttatc taaatgcaaa taaggatgtg ttctctgaga cccatgatca 2800

 ggggatgtgg cggggggtgg ctagagggag aaaaaggaaa tgtcttgtgt 2850

 tgttttgttc ccctgccctc ctttctcagc agctttttgt tattgttgtt 2900

 gttgttctta gacaagtgcc tcctggtgcc tgcggcatcc ttctgcctgt 2950

 ttctgtaagc aaatgccaca ggccacctat agctacatac tcctggcatt 3000

 gcacttttta accttgctga catccaaata gaagatagga ctatctaagc 3050

 cctaggtttc tttttaaatt aagaaataat aacaattaaa gggcaaaaaa 3100

 cactgtatca gcatagcctt tctgtattta agaaacttaa gcagccgggc 3150

 atggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcggatc 3200

 ataaggtcag gagatcaaga ccatcctggc taacacggtg aaaccccgtc 3250

 tctactaaaa gtacaaaaaa ttagctgggt gtggtggtgg gcgcctgtag 3300

 tcccagctac tcgggaggct gaggcaggag aatcgcttga acctgagagg 3350

 cggaggttgc agtgagccaa aattgcacca ctgcacactg cactccatcc 3400

 tgggcgacag tctgagactc tgtctcaaaa aaaaaaaaaa aaaaaaaaaa 3450

 aaaaa 3455

<210> 1894
<211> 770
<212> PRT
<213> Homo sapien

<400> 1894
 Met Ala Gln Trp Asn Gln Leu Gln Gln Leu Asp Thr Arg Tyr Leu
   1               5                  10                  15

 Glu Gln Leu His Gln Leu Tyr Ser Asp Ser Phe Pro Met Glu Leu
                  20                  25                  30

 Arg Gln Phe Leu Ala Pro Trp Ile Glu Ser Gln Asp Trp Ala Tyr
                  35                  40                  45

 Ala Ala Ser Lys Glu Ser His Ala Thr Leu Val Phe His Asn Leu
                  50                  55                  60

 Leu Gly Glu Ile Asp Gln Gln Tyr Ser Arg Phe Leu Gln Glu Ser
                  65                  70                  75

 Asn Val Leu Tyr Gln His Asn Leu Arg Arg Ile Lys Gln Phe Leu
                  80                  85                  90

 Gln Ser Arg Tyr Leu Glu Lys Pro Met Glu Ile Ala Arg Ile Val
                  95                 100                 105

 Ala Arg Cys Leu Trp Glu Glu Ser Arg Leu Leu Gln Thr Ala Ala
                 110                 115                 120

 Thr Ala Ala Gln Gln Gly Gly Gln Ala Asn His Pro Thr Ala Ala
                 125                 130                 135

 Val Val Thr Glu Lys Gln Gln Met Leu Glu Gln His Leu Gln Asp
                 140                 145                 150

 Val Arg Lys Arg Val Gln Asp Leu Glu Gln Lys Met Lys Val Val
                 155                 160                 165

 Glu Asn Leu Gln Asp Asp Phe Asp Phe Asn Tyr Lys Thr Leu Lys
                 170                 175                 180

 Ser Gln Gly Asp Met Gln Asp Leu Asn Gly Asn Asn Gln Ser Val
                 185                 190                 195

 Thr Arg Gln Lys Met Gln Gln Leu Glu Gln Met Leu Thr Ala Leu
                 200                 205                 210

 Asp Gln Met Arg Arg Ser Ile Val Ser Glu Leu Ala Gly Leu Leu
                 215                 220                 225

 Ser Ala Met Glu Tyr Val Gln Lys Thr Leu Thr Asp Glu Glu Leu
                 230                 235                 240

 Ala Asp Trp Lys Arg Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro
                 245                 250                 255

 Pro Asn Ile Cys Leu Asp Arg Leu Glu Asn Trp Ile Thr Ser Leu
                 260                 265                 270

 Ala Glu Ser Gln Leu Gln Thr Arg Gln Gln Ile Lys Lys Leu Glu
                 275                 280                 285

 Glu Leu Gln Gln Lys Val Ser Tyr Lys Gly Asp Pro Ile Val Gln
                 290                 295                 300

 His Arg Pro Met Leu Glu Glu Arg Ile Val Glu Leu Phe Arg Asn
                 305                 310                 315

 Leu Met Lys Ser Ala Phe Val Val Glu Arg Gln Pro Cys Met Pro
                 320                 325                 330

 Met His Pro Asp Arg Pro Leu Val Ile Lys Thr Gly Val Gln Phe
                 335                 340                 345

 Thr Thr Lys Val Arg Leu Leu Val Lys Phe Pro Glu Leu Asn Tyr
                 350                 355                 360

 Gln Leu Lys Ile Lys Val Cys Ile Asp Lys Asp Ser Gly Asp Val
                 365                 370                 375

 Ala Ala Leu Arg Gly Ser Arg Lys Phe Asn Ile Leu Gly Thr Asn
                 380                 385                 390

 Thr Lys Val Met Asn Met Glu Glu Ser Asn Asn Gly Ser Leu Ser
                 395                 400                 405

 Ala Glu Phe Lys His Leu Thr Leu Arg Glu Gln Arg Cys Gly Asn
                 410                 415                 420

 Gly Gly Arg Ala Asn Cys Asp Ala Ser Leu Ile Val Thr Glu Glu
                 425                 430                 435

 Leu His Leu Ile Thr Phe Glu Thr Glu Val Tyr His Gln Gly Leu
                 440                 445                 450

 Lys Ile Asp Leu Glu Thr His Ser Leu Pro Val Val Val Ile Ser
                 455                 460                 465

 Asn Ile Cys Gln Met Pro Asn Ala Trp Ala Ser Ile Leu Trp Tyr
                 470                 475                 480

 Asn Met Leu Thr Asn Asn Pro Lys Asn Val Asn Phe Phe Thr Lys
                 485                 490                 495

 Pro Pro Ile Gly Thr Trp Asp Gln Val Ala Glu Val Leu Ser Trp
                 500                 505                 510

 Gln Phe Ser Ser Thr Thr Lys Arg Gly Leu Ser Ile Glu Gln Leu
                 515                 520                 525

 Thr Thr Leu Ala Glu Lys Leu Leu Gly Pro Gly Val Asn Tyr Ser
                 530                 535                 540

 Gly Cys Gln Ile Thr Trp Ala Lys Phe Cys Lys Glu Asn Met Ala
                 545                 550                 555

 Gly Lys Gly Phe Ser Phe Trp Val Trp Leu Asp Asn Ile Ile Asp
                 560                 565                 570

 Leu Val Lys Lys Tyr Ile Leu Ala Leu Trp Asn Glu Gly Tyr Ile
                 575                 580                 585

 Met Gly Phe Ile Ser Lys Glu Arg Glu Arg Ala Ile Leu Ser Thr
                 590                 595                 600

 Lys Pro Pro Gly Thr Phe Leu Leu Arg Phe Ser Glu Ser Ser Lys
                 605                 610                 615

 Glu Gly Gly Val Thr Phe Thr Trp Val Glu Lys Asp Ile Ser Gly
                 620                 625                 630

 Lys Thr Gln Ile Gln Ser Val Glu Pro Tyr Thr Lys Gln Gln Leu
                 635                 640                 645

 Asn Asn Met Ser Phe Ala Glu Ile Ile Met Gly Tyr Lys Ile Met
                 650                 655                 660

 Asp Ala Thr Asn Ile Leu Val Ser Pro Leu Val Tyr Leu Tyr Pro
                 665                 670                 675

 Asp Ile Pro Lys Glu Glu Ala Phe Gly Lys Tyr Cys Arg Pro Glu
                 680                 685                 690

 Ser Gln Glu His Pro Glu Ala Asp Pro Gly Ser Ala Ala Pro Tyr
                 695                 700                 705

 Leu Lys Thr Lys Phe Ile Cys Val Thr Pro Thr Thr Cys Ser Asn
                 710                 715                 720

 Thr Ile Asp Leu Pro Met Ser Pro Arg Thr Leu Asp Ser Leu Met
                 725                 730                 735

 Gln Phe Gly Asn Asn Gly Glu Gly Ala Glu Pro Ser Ala Gly Gly
                 740                 745                 750

 Gln Phe Glu Ser Leu Thr Phe Asp Met Glu Leu Thr Ser Glu Cys
                 755                 760                 765

 Ala Thr Ser Pro Met
                 770

<210> 1895
<211> 3430
<212> DNA
<213> Homo sapien

<400> 1895
 ggtttccgga gctgcggcgg cgcagactgg gagggggagc cgggggttcc 50

 gacgtcgcag ccgagggaac aagccccaac cggatcctgg acaggcaccc 100

 cggcttggcg ctgtctctcc ccctcggctc ggagaggccc ttcggcctga 150

 gggagcctcg ccgcccgtcc ccggcacacg cgcagccccg gcctctcggc 200

 ctctgccgga gaaacaggat ggcccaatgg aatcagctac agcagcttga 250

 cacacggtac ctggagcagc tccatcagct ctacagtgac agcttcccaa 300

 tggagctgcg gcagtttctg gccccttgga ttgagagtca agattgggca 350

 tatgcggcca gcaaagaatc acatgccact ttggtgtttc ataatctcct 400

 gggagagatt gaccagcagt atagccgctt cctgcaagag tcgaatgttc 450

 tctatcagca caatctacga agaatcaagc agtttcttca gagcaggtat 500

 cttgagaagc caatggagat tgcccggatt gtggcccggt gcctgtggga 550

 agaatcacgc cttctacaga ctgcagccac tgcggcccag caagggggcc 600

 aggccaacca ccccacagca gccgtggtga cggagaagca gcagatgctg 650

 gagcagcacc ttcaggatgt ccggaagaga gtgcaggatc tagaacagaa 700

 aatgaaagtg gtagagaatc tccaggatga ctttgatttc aactataaaa 750

 ccctcaagag tcaaggagac atgcaagatc tgaatggaaa caaccagtca 800

 gtgaccaggc agaagatgca gcagctggaa cagatgctca ctgcgctgga 850

 ccagatgcgg agaagcatcg tgagtgagct ggcggggctt ttgtcagcga 900

 tggagtacgt gcagaaaact ctcacggacg aggagctggc tgactggaag 950

 aggcggcaac agattgcctg cattggaggc ccgcccaaca tctgcctaga 1000

 tcggctagaa aactggataa cgtcattagc agaatctcaa cttcagaccc 1050

 gtcaacaaat taagaaactg gaggagttgc agcaaaaagt ttcctacaaa 1100

 ggggacccca ttgtacagca ccggccgatg ctggaggaga gaatcgtgga 1150

 gctgtttaga aacttaatga aaagtgcctt tgtggtggag cggcagccct 1200

 gcatgcccat gcatcctgac cggcccctcg tcatcaagac cggcgtccag 1250

 ttcactacta aagtcaggtt gctggtcaaa ttccctgagt tgaattatca 1300

 gcttaaaatt aaagtgtgca ttgacaaaga ctctggggac gttgcagctc 1350

 tcagaggatc ccggaaattt aacattctgg gcacaaacac aaaagtgatg 1400

 aacatggaag aatccaacaa cggcagcctc tctgcagaat tcaaacactt 1450

 gaccctgagg gagcagagat gtgggaatgg gggccgagcc aattgtgatg 1500

 cttccctgat tgtgactgag gagctgcacc tgatcacctt tgagaccgag 1550

 gtgtatcacc aaggcctcaa gattgaccta gagacccact ccttgccagt 1600

 tgtggtgatc tccaacatct gtcagatgcc aaatgcctgg gcgtccatcc 1650

 tgtggtacaa catgctgacc aacaatccca agaatgtaaa cttttttacc 1700

 aagcccccaa ttggaacctg ggatcaagtg gccgaggtcc tgagctggca 1750

 gttctcctcc accaccaagc gaggactgag catcgagcag ctgactacac 1800

 tggcagagaa actcttggga cctggtgtga attattcagg gtgtcagatc 1850

 acatgggcta aattttgcaa agaaaacatg gctggcaagg gcttctcctt 1900

 ctgggtctgg ctggacaata tcattgacct tgtgaaaaag tacatcctgg 1950

 ccctttggaa cgaagggtac atcatgggct ttatcagtaa ggagcgggag 2000

 cgggccatct tgagcactaa gcctccaggc accttcctgc taagattcag 2050

 tgaaagcagc aaagaaggag gcgtcacttt cacttgggtg gagaaggaca 2100

 tcagcggtaa gacccagatc cagtccgtgg aaccatacac aaagcagcag 2150

 ctgaacaaca tgtcatttgc tgaaatcatc atgggctata agatcatgga 2200

 tgctaccaat atcctggtgt ctccactggt ctatctctat cctgacattc 2250

 ccaaggagga ggcattcgga aagtattgtc ggccagagag ccaggagcat 2300

 cctgaagctg acccaggcgc tgccccatac ctgaagacca agtttatctg 2350

 tgtgacacca acgacctgca gcaataccat tgacctgccg atgtcccccc 2400

 gcactttaga ttcattgatg cagtttggaa ataatggtga aggtgctgaa 2450

 ccctcagcag gagggcagtt tgagtccctc acctttgaca tggagttgac 2500

 ctcggagtgc gctacctccc ccatgtgagg agctgagaac ggaagctgca 2550

 gaaagatacg actgaggcgc ctacctgcat tctgccaccc ctcacacagc 2600

 caaaccccag atcatctgaa actactaact ttgtggttcc agattttttt 2650

 taatctccta cttctgctat ctttgagcaa tctgggcact tttaaaaata 2700

 gagaaatgag tgaatgtggg tgatctgctt ttatctaaat gcaaataagg 2750

 atgtgttctc tgagacccat gatcagggga tgtggcgggg ggtggctaga 2800

 gggagaaaaa ggaaatgtct tgtgttgttt tgttcccctg ccctcctttc 2850

 tcagcagctt tttgttattg ttgttgttgt tcttagacaa gtgcctcctg 2900

 gtgcctgcgg catccttctg cctgtttctg taagcaaatg ccacaggcca 2950

 cctatagcta catactcctg gcattgcact ttttaacctt gctgacatcc 3000

 aaatagaaga taggactatc taagccctag gtttcttttt aaattaagaa 3050

 ataataacaa ttaaagggca aaaaacactg tatcagcata gcctttctgt 3100

 atttaagaaa cttaagcagc cgggcatggt ggctcacgcc tgtaatccca 3150

 gcactttggg aggccgaggc ggatcataag gtcaggagat caagaccatc 3200

 ctggctaaca cggtgaaacc ccgtctctac taaaagtaca aaaaattagc 3250

 tgggtgtggt ggtgggcgcc tgtagtccca gctactcggg aggctgaggc 3300

 aggagaatcg cttgaacctg agaggcggag gttgcagtga gccaaaattg 3350

 caccactgca cactgcactc catcctgggc gacagtctga gactctgtct 3400

 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3430

<210> 1896
<211> 769
<212> PRT
<213> Homo sapien

<400> 1896
 Met Ala Gln Trp Asn Gln Leu Gln Gln Leu Asp Thr Arg Tyr Leu
   1               5                  10                  15

 Glu Gln Leu His Gln Leu Tyr Ser Asp Ser Phe Pro Met Glu Leu
                  20                  25                  30

 Arg Gln Phe Leu Ala Pro Trp Ile Glu Ser Gln Asp Trp Ala Tyr
                  35                  40                  45

 Ala Ala Ser Lys Glu Ser His Ala Thr Leu Val Phe His Asn Leu
                  50                  55                  60

 Leu Gly Glu Ile Asp Gln Gln Tyr Ser Arg Phe Leu Gln Glu Ser
                  65                  70                  75

 Asn Val Leu Tyr Gln His Asn Leu Arg Arg Ile Lys Gln Phe Leu
                  80                  85                  90

 Gln Ser Arg Tyr Leu Glu Lys Pro Met Glu Ile Ala Arg Ile Val
                  95                 100                 105

 Ala Arg Cys Leu Trp Glu Glu Ser Arg Leu Leu Gln Thr Ala Ala
                 110                 115                 120

 Thr Ala Ala Gln Gln Gly Gly Gln Ala Asn His Pro Thr Ala Ala
                 125                 130                 135

 Val Val Thr Glu Lys Gln Gln Met Leu Glu Gln His Leu Gln Asp
                 140                 145                 150

 Val Arg Lys Arg Val Gln Asp Leu Glu Gln Lys Met Lys Val Val
                 155                 160                 165

 Glu Asn Leu Gln Asp Asp Phe Asp Phe Asn Tyr Lys Thr Leu Lys
                 170                 175                 180

 Ser Gln Gly Asp Met Gln Asp Leu Asn Gly Asn Asn Gln Ser Val
                 185                 190                 195

 Thr Arg Gln Lys Met Gln Gln Leu Glu Gln Met Leu Thr Ala Leu
                 200                 205                 210

 Asp Gln Met Arg Arg Ser Ile Val Ser Glu Leu Ala Gly Leu Leu
                 215                 220                 225

 Ser Ala Met Glu Tyr Val Gln Lys Thr Leu Thr Asp Glu Glu Leu
                 230                 235                 240

 Ala Asp Trp Lys Arg Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro
                 245                 250                 255

 Pro Asn Ile Cys Leu Asp Arg Leu Glu Asn Trp Ile Thr Ser Leu
                 260                 265                 270

 Ala Glu Ser Gln Leu Gln Thr Arg Gln Gln Ile Lys Lys Leu Glu
                 275                 280                 285

 Glu Leu Gln Gln Lys Val Ser Tyr Lys Gly Asp Pro Ile Val Gln
                 290                 295                 300

 His Arg Pro Met Leu Glu Glu Arg Ile Val Glu Leu Phe Arg Asn
                 305                 310                 315

 Leu Met Lys Ser Ala Phe Val Val Glu Arg Gln Pro Cys Met Pro
                 320                 325                 330

 Met His Pro Asp Arg Pro Leu Val Ile Lys Thr Gly Val Gln Phe
                 335                 340                 345

 Thr Thr Lys Val Arg Leu Leu Val Lys Phe Pro Glu Leu Asn Tyr
                 350                 355                 360

 Gln Leu Lys Ile Lys Val Cys Ile Asp Lys Asp Ser Gly Asp Val
                 365                 370                 375

 Ala Ala Leu Arg Gly Ser Arg Lys Phe Asn Ile Leu Gly Thr Asn
                 380                 385                 390

 Thr Lys Val Met Asn Met Glu Glu Ser Asn Asn Gly Ser Leu Ser
                 395                 400                 405

 Ala Glu Phe Lys His Leu Thr Leu Arg Glu Gln Arg Cys Gly Asn
                 410                 415                 420

 Gly Gly Arg Ala Asn Cys Asp Ala Ser Leu Ile Val Thr Glu Glu
                 425                 430                 435

 Leu His Leu Ile Thr Phe Glu Thr Glu Val Tyr His Gln Gly Leu
                 440                 445                 450

 Lys Ile Asp Leu Glu Thr His Ser Leu Pro Val Val Val Ile Ser
                 455                 460                 465

 Asn Ile Cys Gln Met Pro Asn Ala Trp Ala Ser Ile Leu Trp Tyr
                 470                 475                 480

 Asn Met Leu Thr Asn Asn Pro Lys Asn Val Asn Phe Phe Thr Lys
                 485                 490                 495

 Pro Pro Ile Gly Thr Trp Asp Gln Val Ala Glu Val Leu Ser Trp
                 500                 505                 510

 Gln Phe Ser Ser Thr Thr Lys Arg Gly Leu Ser Ile Glu Gln Leu
                 515                 520                 525

 Thr Thr Leu Ala Glu Lys Leu Leu Gly Pro Gly Val Asn Tyr Ser
                 530                 535                 540

 Gly Cys Gln Ile Thr Trp Ala Lys Phe Cys Lys Glu Asn Met Ala
                 545                 550                 555

 Gly Lys Gly Phe Ser Phe Trp Val Trp Leu Asp Asn Ile Ile Asp
                 560                 565                 570

 Leu Val Lys Lys Tyr Ile Leu Ala Leu Trp Asn Glu Gly Tyr Ile
                 575                 580                 585

 Met Gly Phe Ile Ser Lys Glu Arg Glu Arg Ala Ile Leu Ser Thr
                 590                 595                 600

 Lys Pro Pro Gly Thr Phe Leu Leu Arg Phe Ser Glu Ser Ser Lys
                 605                 610                 615

 Glu Gly Gly Val Thr Phe Thr Trp Val Glu Lys Asp Ile Ser Gly
                 620                 625                 630

 Lys Thr Gln Ile Gln Ser Val Glu Pro Tyr Thr Lys Gln Gln Leu
                 635                 640                 645

 Asn Asn Met Ser Phe Ala Glu Ile Ile Met Gly Tyr Lys Ile Met
                 650                 655                 660

 Asp Ala Thr Asn Ile Leu Val Ser Pro Leu Val Tyr Leu Tyr Pro
                 665                 670                 675

 Asp Ile Pro Lys Glu Glu Ala Phe Gly Lys Tyr Cys Arg Pro Glu
                 680                 685                 690

 Ser Gln Glu His Pro Glu Ala Asp Pro Gly Ala Ala Pro Tyr Leu
                 695                 700                 705

 Lys Thr Lys Phe Ile Cys Val Thr Pro Thr Thr Cys Ser Asn Thr
                 710                 715                 720

 Ile Asp Leu Pro Met Ser Pro Arg Thr Leu Asp Ser Leu Met Gln
                 725                 730                 735

 Phe Gly Asn Asn Gly Glu Gly Ala Glu Pro Ser Ala Gly Gly Gln
                 740                 745                 750

 Phe Glu Ser Leu Thr Phe Asp Met Glu Leu Thr Ser Glu Cys Ala
                 755                 760                 765

 Thr Ser Pro Met


<210> 1897
<211> 1646
<212> DNA
<213> Homo sapien

<400> 1897
 cactgcgaag cccagctgcg cgcgccttgg gattgactgt ccacgctcgc 50

 ccggctcgtc cgacgcgccc tccgccagcc gacagacaca gccgcacgca 100

 ctgccgtgtt ctccctgcgg ctcggacaca tagtatgacc attaggtgtt 150

 tcgtctccca cccattttct atggaaaacc aaggggatcg ggccatgata 200

 gccactggca gctttgaaga acgggacacc tttagagaag cttgatcttg 250

 gaggcctcac cgtgagacct tacaaagccg gattccggca gagttcctct 300

 atctcgtctt gttgctgatt aaaggtgccc ctgtctccag tttttctcca 350

 tctcctggga cgtagcagga aatcagcatc atggttgggt tcaaggccac 400

 agatgtgccc cctactgcca ctgtgaagtt tcttggggct ggcacagctg 450

 cctgcatcgc agatctcatc acctttcctc tggatactgc taaagtccgg 500

 ttacagatcc aaggagaaag tcaggggcca gtgcgcgcta cagccagcgc 550

 ccagtaccgc ggtgtgatgg gcaccattct gaccatggtg cgtactgagg 600

 gcccccgaag cctctacaat gggctggttg ccggcctgca gcgccaaatg 650

 agctttgcct ctgtccgcat cggcctgtat gattctgtca aacagttcta 700

 caccaagggc tctgagcatg ccagcattgg gagccgcctc ctagcaggca 750

 gcaccacagg tgccctggct gtggctgtgg cccagcccac ggatgtggta 800

 aaggtccgat tccaagctca ggcccgggct ggaggtggtc ggagatacca 850

 aagcaccgtc aatgcctaca agaccattgc ccgagaggaa gggttccggg 900

 gcctctggaa agggacctct cccaatgttg ctcgtaatgc cattgtcaac 950

 tgtgctgagc tggtgaccta tgacctcatc aaggatgccc tcctgaaagc 1000

 caacctcatg acagatgacc tcccttgcca cttcacttct gcctttgggg 1050

 caggcttctg caccactgtc atcgcctccc ctgtagacgt ggtcaagacg 1100

 agatacatga actctgccct gggccagtac agtagcgctg gccactgtgc 1150

 ccttaccatg ctccagaagg aggggccccg agccttctac aaagggttca 1200

 tgccctcctt tctccgcttg ggttcctgga acgtggtgat gttcgtcacc 1250

 tatgagcagc tgaaacgagc cctcatggct gcctgcactt cccgagaggc 1300

 tcccttctga gcctctcctg ctgctgacct gatcacctct ggctttgtct 1350

 ctagccgggc catgctttcc ttttcttcct tctttctctt ccctccttcc 1400

 cttctctcct tccctctttc cccacctctt ccttccgctc ctttacctac 1450

 caccttccct ctttctacat tctcatctac tcattgtctc agtgctggtg 1500

 gagttgacat ttgacagtgt gggaggcctc gtaccagcca ggatcccaag 1550

 cgtcccgtcc cttggaaagt tcagccagaa tcttcgtcct gcccccgaca 1600

 gcccagccta gcccacttgt catccataaa gcaagctcaa ccttgg 1646

<210> 1898
<211> 309
<212> PRT
<213> Homo sapien

<400> 1898
 Met Val Gly Phe Lys Ala Thr Asp Val Pro Pro Thr Ala Thr Val
   1               5                  10                  15

 Lys Phe Leu Gly Ala Gly Thr Ala Ala Cys Ile Ala Asp Leu Ile
                  20                  25                  30

 Thr Phe Pro Leu Asp Thr Ala Lys Val Arg Leu Gln Ile Gln Gly
                  35                  40                  45

 Glu Ser Gln Gly Pro Val Arg Ala Thr Ala Ser Ala Gln Tyr Arg
                  50                  55                  60

 Gly Val Met Gly Thr Ile Leu Thr Met Val Arg Thr Glu Gly Pro
                  65                  70                  75

 Arg Ser Leu Tyr Asn Gly Leu Val Ala Gly Leu Gln Arg Gln Met
                  80                  85                  90

 Ser Phe Ala Ser Val Arg Ile Gly Leu Tyr Asp Ser Val Lys Gln
                  95                 100                 105

 Phe Tyr Thr Lys Gly Ser Glu His Ala Ser Ile Gly Ser Arg Leu
                 110                 115                 120

 Leu Ala Gly Ser Thr Thr Gly Ala Leu Ala Val Ala Val Ala Gln
                 125                 130                 135

 Pro Thr Asp Val Val Lys Val Arg Phe Gln Ala Gln Ala Arg Ala
                 140                 145                 150

 Gly Gly Gly Arg Arg Tyr Gln Ser Thr Val Asn Ala Tyr Lys Thr
                 155                 160                 165

 Ile Ala Arg Glu Glu Gly Phe Arg Gly Leu Trp Lys Gly Thr Ser
                 170                 175                 180

 Pro Asn Val Ala Arg Asn Ala Ile Val Asn Cys Ala Glu Leu Val
                 185                 190                 195

 Thr Tyr Asp Leu Ile Lys Asp Ala Leu Leu Lys Ala Asn Leu Met
                 200                 205                 210

 Thr Asp Asp Leu Pro Cys His Phe Thr Ser Ala Phe Gly Ala Gly
                 215                 220                 225

 Phe Cys Thr Thr Val Ile Ala Ser Pro Val Asp Val Val Lys Thr
                 230                 235                 240

 Arg Tyr Met Asn Ser Ala Leu Gly Gln Tyr Ser Ser Ala Gly His
                 245                 250                 255

 Cys Ala Leu Thr Met Leu Gln Lys Glu Gly Pro Arg Ala Phe Tyr
                 260                 265                 270

 Lys Gly Phe Met Pro Ser Phe Leu Arg Leu Gly Ser Trp Asn Val
                 275                 280                 285

 Val Met Phe Val Thr Tyr Glu Gln Leu Lys Arg Ala Leu Met Ala
                 290                 295                 300

 Ala Cys Thr Ser Arg Glu Ala Pro Phe
                 305

<210> 1899
<211> 4344
<212> DNA
<213> Homo sapien

<400> 1899
 gcggcggggc tccggctgcg ctcgtggccg ggccgggcgg ggaggccggt 50

 cccgcgggcg ggggcagggg cggctccgcg gcttctcccg ccgccgccgc 100

 caaggggagt ttccaggaag tggccatatt ggatccattc agccgcagcc 150

 gcccgggcgg agcgcgtccc gcagccggct ggtccctgtc gctgcccctg 200

 cgctcgtccc agcccacccg cccggtgcgg agctcgccat ggcggccacc 250

 gacctggagc gcttctcgaa tgcagagcca gagccccgga gcctctccct 300

 gggcggccat gtgggtttcg acagcctccc cgaccagctg gtcagcaagt 350

 cggtcactca gggcttcagc ttcaacatcc tctgtgtggg ggagaccggc 400

 attggcaaat ccacactgat gaacacactc ttcaacacga ccttcgagac 450

 tgaggaagcc agtcaccatg aggcatgcgt gcgcctgcgg ccccagacct 500

 acgacctcca ggagagcaac gtgcagctca agctgaccat tgtggatgcc 550

 gtgggctttg gggatcagat caataaggat gagagttaca ggcccatagt 600

 tgactacatc gatgcgcagt ttgaaaatta tctgcaggag gagctgaaga 650

 tccgccgctc gctcttcgac taccatgaca caaggatcca cgtttgcctc 700

 tacttcatca cgcccacagg gcactccctg aagtctctag atctagtgac 750

 catgaagaaa ctagacagca aggtgaacat tattcccatc atcgccaagg 800

 ctgacaccat ctccaagagc gagctccaca agttcaagat caagatcatg 850

 ggcgagttgg tcagcaacgg ggtccagatc taccagttcc ccacggatga 900

 tgaggctgtt gcagagatta acgcagtcat gaatgcacat ctgccctttg 950

 ccgtggtggg cagcaccgag gaggtgaagg tggggaacaa gctggtccga 1000

 gcacggcagt acccctgggg agtggtgcag gtggagaatg agaatcactg 1050

 cgacttcgtg aagctgcggg agatgttgat ccgggtgaac atggaagacc 1100

 tccgcgagca gacccacagc cggcactacg agctctaccg gcgctgcaag 1150

 ttggaggaga tgggctttca ggacagcgat ggtgacagcc agcccttcag 1200

 cctacaagag acatacgagg ccaagaggaa ggagttccta agtgagctgc 1250

 agaggaagga ggaagagatg aggcagatgt ttgtcaacaa agtgaaggag 1300

 acagagctgg agctgaagga gaaggaaagg gagctccatg agaagtttga 1350

 gcacctgaag cgggtccacc aggaggagaa gcgcaaggtg gaggaaaagc 1400

 gccgggaact ggaggaggag accaacgcct tcaatcgccg gaaggctgcg 1450

 gtggaggccc tgcagtcgca ggccttgcac gccacctcgc agcagcccct 1500

 gaggaaggac aaggacaaga agaattaacg cacgcacaga cttacatgtc 1550

 aagagtggac tttagacttt catgtgttaa gttgcttgag ttacaccttg 1600

 tgacccttct cccataacat ggtgtgagga cggactggga gccggtacag 1650

 actccagtgt ttacagcctt gctttcctcc caccgaccct ggccccaggc 1700

 tgccccgggc ctggcgggcc acccctctct atgcaaacac gtaaaagcca 1750

 tgaatgctgg aatccaaaac tgacgaggtt tatttttttc agagccagtg 1800

 gctggtcttc catttacagt gtcactattc cctgacggag ctgttatgtg 1850

 ccgctctagc gaaggcccca gccgggatgc taggcctaat tgttcagcgt 1900

 ggagatggca actcacgtgg tgccctaggt gcagctgcgt ggtctggtat 1950

 acatgctgca aaattcaccc agttcccctc attttaattt ttctaaccta 2000

 cagcttaatt ttaataactt taaaacactt ctaaatattt attttgacac 2050

 cagcgtcaag acaaataata tcctctccca ttattttcat aagtaacaca 2100

 gattccctga tttttaaaaa ctaaaaatac agctaaacct ttcttatgta 2150

 taaagtatgc ctatcatata cagggagagg tgggtaataa acttcctgta 2200

 atgacagtgt ttggcatttc tttatggatg gaattggaac atgaacaaga 2250

 ccatgtccag cgtttttact gtgaatgtaa atggaacagc agcccaaagc 2300

 tgttgtctgt gccccagagg tgctacctgt agacagggac caactccatg 2350

 tgtgtgtgtt aagtgtttga ctccaattaa gactcccaag cgaatcctgc 2400

 atattccaaa tgtaaagagt actcagtggg aaaaaggttg ttacctcaaa 2450

 gtcattgctt ctttcctggc tgggtcacag ggtgaagaga tgaaggtgtc 2500

 tgatgtatat agacaattag ggaaaaatga gcggcaaagg agctttcccc 2550

 ttcagctgca ctctaaaggg gaacatttta aggaagtact agcagctttg 2600

 actcttctat gctcctgttg gtttacaagc caccaagaat gtcagtgttg 2650

 agaatacggc ctggtaaaat gggagatgta aaatgactaa atgaaaggaa 2700

 gggtagtttt aatgttgaag caccgtgctg ggcactggag ctacccagag 2750

 gaatgcacaa cgctcccctc aaggagctca cagtctagcc tactccctgg 2800

 ctggaagcct caggaagacg tgctaattta ttgtggaatt ggtagtttgc 2850

 ttttcatgcc cctgtcttcc ttctcatgac catttccccc tttctgtctg 2900

 gcttgcatta ttgatttcca ggaccaagtc ctggcttcct cctgccttcc 2950

 tgagatgatg ttctgctcag ggagaagtgg aggggtgagc tatgtgtgtc 3000

 caccgaggca cggccaggaa gaggcagcct ttacctgtga ggggctccat 3050

 gctccagcag cagagcaggt tctagtgaca attcaacttt ttatgctatg 3100

 accaggggtg gatctaaatt ttatggggct gaaagcttga attatttaga 3150

 aagacttctt taagaaaaac aatgttaata taaaattagg tacagggtct 3200

 tggaaggggc cctgaagatt aagcttcctt agcgtcacaa taagtccgta 3250

 tctggttgca attgaaaact gatgcttcag tgagggtatc taaaaaggta 3300

 aactggcata tccagggcaa atgtgggctg ccaatggctc atctctaggg 3350

 taattttatg tctgaaagtg tatgcagttg ggtcagagca tgacctttaa 3400

 gatagcctct ctcagctaac atatttatga agatgaggcc tggtgaccca 3450

 gcaggttcat tggatacata agaaatgaga attcctggtt catgggccaa 3500

 cctaggactc tggagtatgc agacttggcc attcgtccat tgtggcctgc 3550

 gggtcgcacc ccaggcatac tgaaaggcca tactcgtggc tggctgcctg 3600

 cgggcctaag ccttcccagg atcttcagga cacttgacag acttgtgttt 3650

 tctggtctga gctgcctcca caggtccctc cagcaagcct cactgcacct 3700

 ctcccctgct gtttgtgttt ggaattttgt cttctttagc tgagaccaaa 3750

 ttaaaccttg gtgcataaag tgagcttaaa acttgccact gtttagtaag 3800

 ttagccccca tagaatgtga ccctgtctgc agagtctcat ttacccctct 3850

 ttttctcatt gtcatttgtt ggctttatta gggctgtctt acaggatcat 3900

 gttggcattt actatcatgt ctttatcata aaccatgttt gtttgaggta 3950

 gaagaatcac catataattc gttgcccaaa ttgggactat tgagagagaa 4000

 aggggatgct attaattaca ccagatcaaa aggcataaac cagacctgtc 4050

 ccaggccgat gtggaaatat gttctttcta gttgtgggta ccctgatcta 4100

 ggtggtttgt aattgtgcat tactgactgc atatgtttgt gtatgtgtaa 4150

 atgtgggctc cctgttaagt ggggctcatg gatacgaggc ctgaggaagt 4200

 gtggcttgct agtctgttac gttaacatgc ttttctaaaa ttgcttcacg 4250

 tgttaattca tttactcctg cattcattga ctgtttttgt tcttttccat 4300

 tcactttgta cttatttttt tcattaaatt ttgcatttat tttg 4344

<210> 1900
<211> 508
<212> PRT
<213> Homo sapien

<400> 1900
 Arg Arg Gly Ser Gly Cys Ala Arg Gly Arg Ala Gly Arg Gly Gly
   1               5                  10                  15

 Arg Ser Arg Gly Arg Gly Gln Gly Arg Leu Arg Gly Phe Ser Arg
                  20                  25                  30

 Arg Arg Arg Gln Gly Glu Phe Pro Gly Ser Gly His Ile Gly Ser
                  35                  40                  45

 Ile Gln Pro Gln Pro Pro Gly Arg Ser Ala Ser Arg Ser Arg Leu
                  50                  55                  60

 Val Pro Val Ala Ala Pro Ala Leu Val Pro Ala His Pro Pro Gly
                  65                  70                  75

 Ala Glu Leu Ala Met Ala Ala Thr Asp Leu Glu Arg Phe Ser Asn
                  80                  85                  90

 Ala Glu Pro Glu Pro Arg Ser Leu Ser Leu Gly Gly His Val Gly
                  95                 100                 105

 Phe Asp Ser Leu Pro Asp Gln Leu Val Ser Lys Ser Val Thr Gln
                 110                 115                 120

 Gly Phe Ser Phe Asn Ile Leu Cys Val Gly Glu Thr Gly Ile Gly
                 125                 130                 135

 Lys Ser Thr Leu Met Asn Thr Leu Phe Asn Thr Thr Phe Glu Thr
                 140                 145                 150

 Glu Glu Ala Ser His His Glu Ala Cys Val Arg Leu Arg Pro Gln
                 155                 160                 165

 Thr Tyr Asp Leu Gln Glu Ser Asn Val Gln Leu Lys Leu Thr Ile
                 170                 175                 180

 Val Asp Ala Val Gly Phe Gly Asp Gln Ile Asn Lys Asp Glu Ser
                 185                 190                 195

 Tyr Arg Pro Ile Val Asp Tyr Ile Asp Ala Gln Phe Glu Asn Tyr
                 200                 205                 210

 Leu Gln Glu Glu Leu Lys Ile Arg Arg Ser Leu Phe Asp Tyr His
                 215                 220                 225

 Asp Thr Arg Ile His Val Cys Leu Tyr Phe Ile Thr Pro Thr Gly
                 230                 235                 240

 His Ser Leu Lys Ser Leu Asp Leu Val Thr Met Lys Lys Leu Asp
                 245                 250                 255

 Ser Lys Val Asn Ile Ile Pro Ile Ile Ala Lys Ala Asp Thr Ile
                 260                 265                 270

 Ser Lys Ser Glu Leu His Lys Phe Lys Ile Lys Ile Met Gly Glu
                 275                 280                 285

 Leu Val Ser Asn Gly Val Gln Ile Tyr Gln Phe Pro Thr Asp Asp
                 290                 295                 300

 Glu Ala Val Ala Glu Ile Asn Ala Val Met Asn Ala His Leu Pro
                 305                 310                 315

 Phe Ala Val Val Gly Ser Thr Glu Glu Val Lys Val Gly Asn Lys
                 320                 325                 330

 Leu Val Arg Ala Arg Gln Tyr Pro Trp Gly Val Val Gln Val Glu
                 335                 340                 345

 Asn Glu Asn His Cys Asp Phe Val Lys Leu Arg Glu Met Leu Ile
                 350                 355                 360

 Arg Val Asn Met Glu Asp Leu Arg Glu Gln Thr His Ser Arg His
                 365                 370                 375

 Tyr Glu Leu Tyr Arg Arg Cys Lys Leu Glu Glu Met Gly Phe Gln
                 380                 385                 390

 Asp Ser Asp Gly Asp Ser Gln Pro Phe Ser Leu Gln Glu Thr Tyr
                 395                 400                 405

 Glu Ala Lys Arg Lys Glu Phe Leu Ser Glu Leu Gln Arg Lys Glu
                 410                 415                 420

 Glu Glu Met Arg Gln Met Phe Val Asn Lys Val Lys Glu Thr Glu
                 425                 430                 435

 Leu Glu Leu Lys Glu Lys Glu Arg Glu Leu His Glu Lys Phe Glu
                 440                 445                 450

 His Leu Lys Arg Val His Gln Glu Glu Lys Arg Lys Val Glu Glu
                 455                 460                 465

 Lys Arg Arg Glu Leu Glu Glu Glu Thr Asn Ala Phe Asn Arg Arg
                 470                 475                 480

 Lys Ala Ala Val Glu Ala Leu Gln Ser Gln Ala Leu His Ala Thr
                 485                 490                 495

 Ser Gln Gln Pro Leu Arg Lys Asp Lys Asp Lys Lys Asn
                 500                 505

<210> 1901
<211> 3371
<212> DNA
<213> Homo sapien

<400> 1901
 gcgggcgcat gcgcaagggg gcgcgccgcc tctgccccgc ggcgagggtg 50

 tctatggaga ggcggcggcc gcggctgctg aggcggaggc tgaggcagtg 100

 gcgatggcgc cctttcctga agaagtggac gtcttcaccg ccccacactg 150

 gcggatgaag cagctggtgg ggctctactg cgacaagctt tctaaaacca 200

 atttttccaa caacaacgat ttccgtgctc ttctgcagtc tttgtatgct 250

 actttcaagg agttcaaaat gcatgagcag attgaaaatg aatacattat 300

 tggtttgctt caacaacgca gccagaccat ttataatgta cattctgaca 350

 ataaactctc cgagatgctt agcctctttg aaaagggact gaagaatgtt 400

 aagaatgaat atgaacagtt aaattatgca aaacaactga aagagagatt 450

 ggaggctttt acaagagatt ttcttcctca catgaaagag gaagaggagg 500

 tttttcagcc catgttaatg gaatatttta cctatgaaga gcttaaggat 550

 attaaaaaga aagtgattgc acaacactgc tctcagaagg atactgcaga 600

 actccttaga ggtcttagcc tatggaatca tgctgaagag cgacagaagt 650

 tttttaaata ttccgtggat gaaaagtcag ataaagaagc agaagtgtca 700

 gaacactcca caggtataac ccatcttcct cctgaggtaa tgctgtcaat 750

 tttcagctat cttaatcctc aagagttatg tcgatgcagt caagtaagca 800

 tgaaatggtc tcagctgaca aaaacgggat cgctttggaa acatctttac 850

 cctgttcatt gggccagagg tgactggtat agtggtcccg caactgaact 900

 tgatactgaa cctgatgatg aatgggtgaa aaataggaaa gatgaaagtc 950

 gtgcttttca tgagtgggat gaagatgctg acattgatga atctgaagag 1000

 tctgcggagg aatcaattgc tatcagcatt gcacaaatgg aaaaacgttt 1050

 actccatggc ttaattcata acgttctacc atatgttggt acttctgtaa 1100

 aaaccttagt attagcatac agctctgcag tttccagcaa aatggttagg 1150

 cagattttag agctttgtcc taacctggag catctggatc ttacccagac 1200

 tgacatttca gattctgcat ttgacagttg gtcttggctt ggttgctgcc 1250

 agagtcttcg gcatcttgat ctgtctggtt gtgagaaaat cacagatgtg 1300

 gccctagaga agatttccag agctcttgga attctgacat ctcatcaaag 1350

 tggctttttg aaaacatcta caagcaaaat tacttcaact gcgtggaaaa 1400

 ataaagacat taccatgcag tccaccaagc agtatgcctg tttgcacgat 1450

 ttaactaaca agggcattgg agaagaaata gataatgaac acccctggac 1500

 taagcctgtt tcttctgaga atttcacttc tccttatgtg tggatgttag 1550

 atgctgaaga tttggctgat attgaagata ctgtggaatg gagacataga 1600

 aatgttgaaa gtctttgtgt aatggaaaca gcatccaact ttagttgttc 1650

 cacctctggt tgttttagta aggacattgt tggactaagg actagtgtct 1700

 gttggcagca gcattgtgct tctccagcct ttgcgtattg tggtcactca 1750

 ttttgttgta caggaacagc tttaagaact atgtcatcac tcccagaatc 1800

 ttctgcaatg tgtagaaaag cagcaaggac tagattgcct aggggaaaag 1850

 acttaattta ctttgggagt gaaaaatctg atcaagagac tggacgtgta 1900

 cttctgtttc tcagtttatc tggatgttat cagatcacag accatggtct 1950

 cagggttttg actctgggag gagggctgcc ttatttggag caccttaatc 2000

 tctctggttg tcttactata actggtgcag gcctgcagga tttggtttca 2050

 gcatgtcctt ctctgaatga tgaatacttt tactactgtg acaacattaa 2100

 cggtcctcat gctgataccg ccagtggatg ccagaatttg cagtgtggtt 2150

 ttcgagcctg ctgccgctct ggcgaatgac ccttgacttc tgatctttgt 2200

 ctacttcatt tagctgagca ggctttcttt catgcacttt actcatagca 2250

 catttcttgt gttaaccatc cctttttgag cgtgacttgt tttggcccca 2300

 tttcttacaa cttcagaaat cttaatttac cagtgaattg taatgttgtt 2350

 tctcttgcaa attatacttt tggtttagaa agggattagg tcttttcaaa 2400

 agggtgagaa cagtcttaca tttttctttt aaatgaaatg ctttaaagaa 2450

 tgttggtaat gccatgtcat ttaaagtatt tcatagataa ttttgagttt 2500

 taaagtccat ggaggtgatt ggttctcttt acacattaac actgtaccaa 2550

 gctttgcaga tcttttccga cacacatgtc tgaagactta ttttcaaaga 2600

 cagcacattt ttggaaacta atctcttttc cgtaatattt cctttatttc 2650

 aatgattctc agaaggccaa ttcaaacaaa cccacattta aggttcttta 2700

 ggattataga ataaattggc ttctgagtgt tagctcagtg agctaggaaa 2750

 gcaccaatcg atatttgttt cctttaggga tactttgttc tcaccactgt 2800

 ccctatgtca tcaaatttgg gagagatttt ttaaaatacc acaatcattt 2850

 gaagaaatgt ataaataaaa tctactttga ggactttacc aagtaatact 2900

 gttgtgttgt gatttttatt ataaatctca atccaggttt actttagtat 2950

 agaataggac tacatacttt gtctttggac ctcccatgaa cttattaccc 3000

 tgacaaatag ttttagacag atactgaatt ttattgagct gaattttctt 3050

 tttgaaatga gttattcagt agtcaaaatt tgaatccgta agtatatcta 3100

 ctttgctttg ttaaaacatc atgagagtgg aggcctgcca cccagaaagg 3150

 cacatactag tgccttttag tacaatttta tgtcatgtag aagaaaatgg 3200

 caatgttcct cctattgata cagatacagg catatgtcat cttattgcgt 3250

 tttgctttat tgcactttgc aaataatgca ttttttacaa atggaaggtt 3300

 tatggcaact ctgcgttgag ccagtctatt ggtgccatgt ttccaataaa 3350

 acttctcctt tcatgtctcg t 3371

<210> 1902
<211> 691
<212> PRT
<213> Homo sapien

<400> 1902
 Met Ala Pro Phe Pro Glu Glu Val Asp Val Phe Thr Ala Pro His
   1               5                  10                  15

 Trp Arg Met Lys Gln Leu Val Gly Leu Tyr Cys Asp Lys Leu Ser
                  20                  25                  30

 Lys Thr Asn Phe Ser Asn Asn Asn Asp Phe Arg Ala Leu Leu Gln
                  35                  40                  45

 Ser Leu Tyr Ala Thr Phe Lys Glu Phe Lys Met His Glu Gln Ile
                  50                  55                  60

 Glu Asn Glu Tyr Ile Ile Gly Leu Leu Gln Gln Arg Ser Gln Thr
                  65                  70                  75

 Ile Tyr Asn Val His Ser Asp Asn Lys Leu Ser Glu Met Leu Ser
                  80                  85                  90

 Leu Phe Glu Lys Gly Leu Lys Asn Val Lys Asn Glu Tyr Glu Gln
                  95                 100                 105

 Leu Asn Tyr Ala Lys Gln Leu Lys Glu Arg Leu Glu Ala Phe Thr
                 110                 115                 120

 Arg Asp Phe Leu Pro His Met Lys Glu Glu Glu Glu Val Phe Gln
                 125                 130                 135

 Pro Met Leu Met Glu Tyr Phe Thr Tyr Glu Glu Leu Lys Asp Ile
                 140                 145                 150

 Lys Lys Lys Val Ile Ala Gln His Cys Ser Gln Lys Asp Thr Ala
                 155                 160                 165

 Glu Leu Leu Arg Gly Leu Ser Leu Trp Asn His Ala Glu Glu Arg
                 170                 175                 180

 Gln Lys Phe Phe Lys Tyr Ser Val Asp Glu Lys Ser Asp Lys Glu
                 185                 190                 195

 Ala Glu Val Ser Glu His Ser Thr Gly Ile Thr His Leu Pro Pro
                 200                 205                 210

 Glu Val Met Leu Ser Ile Phe Ser Tyr Leu Asn Pro Gln Glu Leu
                 215                 220                 225

 Cys Arg Cys Ser Gln Val Ser Met Lys Trp Ser Gln Leu Thr Lys
                 230                 235                 240

 Thr Gly Ser Leu Trp Lys His Leu Tyr Pro Val His Trp Ala Arg
                 245                 250                 255

 Gly Asp Trp Tyr Ser Gly Pro Ala Thr Glu Leu Asp Thr Glu Pro
                 260                 265                 270

 Asp Asp Glu Trp Val Lys Asn Arg Lys Asp Glu Ser Arg Ala Phe
                 275                 280                 285

 His Glu Trp Asp Glu Asp Ala Asp Ile Asp Glu Ser Glu Glu Ser
                 290                 295                 300

 Ala Glu Glu Ser Ile Ala Ile Ser Ile Ala Gln Met Glu Lys Arg
                 305                 310                 315

 Leu Leu His Gly Leu Ile His Asn Val Leu Pro Tyr Val Gly Thr
                 320                 325                 330

 Ser Val Lys Thr Leu Val Leu Ala Tyr Ser Ser Ala Val Ser Ser
                 335                 340                 345

 Lys Met Val Arg Gln Ile Leu Glu Leu Cys Pro Asn Leu Glu His
                 350                 355                 360

 Leu Asp Leu Thr Gln Thr Asp Ile Ser Asp Ser Ala Phe Asp Ser
                 365                 370                 375

 Trp Ser Trp Leu Gly Cys Cys Gln Ser Leu Arg His Leu Asp Leu
                 380                 385                 390

 Ser Gly Cys Glu Lys Ile Thr Asp Val Ala Leu Glu Lys Ile Ser
                 395                 400                 405

 Arg Ala Leu Gly Ile Leu Thr Ser His Gln Ser Gly Phe Leu Lys
                 410                 415                 420

 Thr Ser Thr Ser Lys Ile Thr Ser Thr Ala Trp Lys Asn Lys Asp
                 425                 430                 435

 Ile Thr Met Gln Ser Thr Lys Gln Tyr Ala Cys Leu His Asp Leu
                 440                 445                 450

 Thr Asn Lys Gly Ile Gly Glu Glu Ile Asp Asn Glu His Pro Trp
                 455                 460                 465

 Thr Lys Pro Val Ser Ser Glu Asn Phe Thr Ser Pro Tyr Val Trp
                 470                 475                 480

 Met Leu Asp Ala Glu Asp Leu Ala Asp Ile Glu Asp Thr Val Glu
                 485                 490                 495

 Trp Arg His Arg Asn Val Glu Ser Leu Cys Val Met Glu Thr Ala
                 500                 505                 510

 Ser Asn Phe Ser Cys Ser Thr Ser Gly Cys Phe Ser Lys Asp Ile
                 515                 520                 525

 Val Gly Leu Arg Thr Ser Val Cys Trp Gln Gln His Cys Ala Ser
                 530                 535                 540

 Pro Ala Phe Ala Tyr Cys Gly His Ser Phe Cys Cys Thr Gly Thr
                 545                 550                 555

 Ala Leu Arg Thr Met Ser Ser Leu Pro Glu Ser Ser Ala Met Cys
                 560                 565                 570

 Arg Lys Ala Ala Arg Thr Arg Leu Pro Arg Gly Lys Asp Leu Ile
                 575                 580                 585

 Tyr Phe Gly Ser Glu Lys Ser Asp Gln Glu Thr Gly Arg Val Leu
                 590                 595                 600

 Leu Phe Leu Ser Leu Ser Gly Cys Tyr Gln Ile Thr Asp His Gly
                 605                 610                 615

 Leu Arg Val Leu Thr Leu Gly Gly Gly Leu Pro Tyr Leu Glu His
                 620                 625                 630

 Leu Asn Leu Ser Gly Cys Leu Thr Ile Thr Gly Ala Gly Leu Gln
                 635                 640                 645

 Asp Leu Val Ser Ala Cys Pro Ser Leu Asn Asp Glu Tyr Phe Tyr
                 650                 655                 660

 Tyr Cys Asp Asn Ile Asn Gly Pro His Ala Asp Thr Ala Ser Gly
                 665                 670                 675

 Cys Gln Asn Leu Gln Cys Gly Phe Arg Ala Cys Cys Arg Ser Gly
                 680                 685                 690

 Glu


<210> 1903
<211> 1962
<212> DNA
<213> Homo sapien

<400> 1903
 agtgcgcatc cggacgtagg aggtggaggt tgtggaattc gccgttcgaa 50

 agcagggact aaaagcccca cttcgtctta cgttccgaaa ggaaggcgtc 100

 tgttgagcct ttctctcagt cgtgagggag gcgtcgacgg cgtgcggaag 150

 tcctgagttg aggcttgcgg gatcctttcc ggagaaagcg caggctaaag 200

 ccgcaggtga agatgtccaa ctacgtgaac gacatgtggc cgggctcgcc 250

 gcaggagaag gattcgccct cgacctcgcg gtcgggcggg tccagccggc 300

 tgtcgtcgcg gtctaggagc cgctcttttt ccagaagctc tcggtcccat 350

 tcccgcgtct cgagccggtt ttcgtccagg agtcggagga gcaagtccag 400

 gtcccgttcc cgaaggcgcc accagcggaa gtacaggcgc tactcgcggt 450

 catactcgcg gagccggtcg cgatcccgca gccgccgtta ccgagagagg 500

 cgctacgggt tcaccaggag atactaccgg tctccttcgc ggtaccggtc 550

 ccggtcccgt agcaggtcgc gctctcgggg aaggtcgtac tgcggaaggg 600

 cgtacgcgat cgcgcgggga cagcgctact acggctttgg tcgcacagtg 650

 tacccggagg agcacagcag atggagggac agatccagga cgaggtcgcg 700

 gagcagaacc ccctttcgct taagtgaaaa agatcgaatg gagctgttag 750

 aaatagcaaa aaccaatgca gcgaaagctc taggaacaac caacattgac 800

 ttgccagcta gtctcagaac tgttccttca gccaaagaaa caagccgtgg 850

 aataggtgta tcaagtaatg gtgcaaagcc tgaagtaagt attctaggtt 900

 tgtcggaaca aaactttcag aaagccaact gtcaaatctg attagccact 950

 tatatcttag actatacttt ttgggaagtc tagagatgta tataatgtgc 1000

 taaattcaaa gtagcaaatc tgaagatagg caatgtcaaa cccatgaaaa 1050

 tgggagatta atgagcttta tttggccgtg catggtgcct catgcctgta 1100

 atgaggcaga tggcttgagt ccaggagttc aagactagcc tgggcaatgt 1150

 ggcaaaaccg cgtgtttaca aaaaatacaa aaattagcca ggcatggtgg 1200

 tgcatgcctg tagtcccagc tgtttgggag gctgaggcag gaggatcttt 1250

 gagcctagga tgctaaggtt gcagtgagcc aagatggcac cattgcactc 1300

 tagcctgggc agcagagcga gaccctgtct caaaaaatac atttattttt 1350

 ttcattttca gttaacagtg tactcttata acaccgttat tagctggtac 1400

 tttggtgatt tctattacta gtttttctaa gctatttaca gagtgtttgt 1450

 agctttcatt tgcagcatta tgttcccaca aattctgtac tcagcatata 1500

 cagtatagtt tatctgctct atttctgtct tatagaaatc atgaatgtgg 1550

 tctgcagaca ttgatgaaga aaatctgttg gtaattgata catgggctaa 1600

 agcatcagag gtttaatttg aagtttatgt tcacacactg aaaacttagt 1650

 ttttttgttg gtagatccat gtgcatgcta gaatttggga caggcactat 1700

 ttgcataaag tattaaagtc aatttttaaa ctaagcaaag gtacacgttg 1750

 taacggtggg gcatctgtga aaaagatgtc cctttcataa tatatgcaat 1800

 atattccaga tgttttgaga gattacagaa gaggaggcct gcttcacttg 1850

 cagataagtt tattataatt ctccagaaat gtgcaggatg tgcattagca 1900

 aattgcactg tacttttcac tccagcctgg gtgacagagc aagactcccg 1950

 tctcgggggc tt 1962

<210> 1904
<211> 242
<212> PRT
<213> Homo sapien

<400> 1904
 Met Ser Asn Tyr Val Asn Asp Met Trp Pro Gly Ser Pro Gln Glu
   1               5                  10                  15

 Lys Asp Ser Pro Ser Thr Ser Arg Ser Gly Gly Ser Ser Arg Leu
                  20                  25                  30

 Ser Ser Arg Ser Arg Ser Arg Ser Phe Ser Arg Ser Ser Arg Ser
                  35                  40                  45

 His Ser Arg Val Ser Ser Arg Phe Ser Ser Arg Ser Arg Arg Ser
                  50                  55                  60

 Lys Ser Arg Ser Arg Ser Arg Arg Arg His Gln Arg Lys Tyr Arg
                  65                  70                  75

 Arg Tyr Ser Arg Ser Tyr Ser Arg Ser Arg Ser Arg Ser Arg Ser
                  80                  85                  90

 Arg Arg Tyr Arg Glu Arg Arg Tyr Gly Phe Thr Arg Arg Tyr Tyr
                  95                 100                 105

 Arg Ser Pro Ser Arg Tyr Arg Ser Arg Ser Arg Ser Arg Ser Arg
                 110                 115                 120

 Ser Arg Gly Arg Ser Tyr Cys Gly Arg Ala Tyr Ala Ile Ala Arg
                 125                 130                 135

 Gly Gln Arg Tyr Tyr Gly Phe Gly Arg Thr Val Tyr Pro Glu Glu
                 140                 145                 150

 His Ser Arg Trp Arg Asp Arg Ser Arg Thr Arg Ser Arg Ser Arg
                 155                 160                 165

 Thr Pro Phe Arg Leu Ser Glu Lys Asp Arg Met Glu Leu Leu Glu
                 170                 175                 180

 Ile Ala Lys Thr Asn Ala Ala Lys Ala Leu Gly Thr Thr Asn Ile
                 185                 190                 195

 Asp Leu Pro Ala Ser Leu Arg Thr Val Pro Ser Ala Lys Glu Thr
                 200                 205                 210

 Ser Arg Gly Ile Gly Val Ser Ser Asn Gly Ala Lys Pro Glu Val
                 215                 220                 225

 Ser Ile Leu Gly Leu Ser Glu Gln Asn Phe Gln Lys Ala Asn Cys
                 230                 235                 240

 Gln Ile


<210> 1905
<211> 1431
<212> DNA
<213> Homo sapien

<400> 1905
 ggacgtagga ggtggaggtt gtggaattcg ccgttcgaaa gcagggacta 50

 aaagccccac ttcgtcttac gttccgaaag gaaggcgtct gttgagcctt 100

 tctctcagtc gtgagggagg cgtcgacggc gtgcggaagt cctgagttga 150

 ggcttgcggg atcctttccg gagaaagcgc aggctaaagc cgcaggtgaa 200

 gatgtccaac tacgtgaacg acatgtggcc gggctcgccg caggagaagg 250

 attcgccctc gacctcgcgg tcgggcgggt ccagccggct gtcgtcgcgg 300

 tctaggagcc gctctttttc cagaagctct cggtcccatt cccgcgtctc 350

 gagccggttt tcgtccagga gtcggaggag caagtccagg tcccgttccc 400

 gaaggcgcca ccagcggaag tacaggcgct actcgcggtc atactcgcgg 450

 agccggtcgc gatcccgcag ccgccgttac cgagagaggc gctacgggtt 500

 caccaggaga tactaccggt ctccttcgcg gtaccggtcc cggtcccgta 550

 gcaggtcgcg ctctcgggga aggtcgtact gcggaagggc gtacgcgatc 600

 gcgcggggac agcgctacta cggctttggt cgcacagtgt acccggagga 650

 gcacagcaga tggagggaca gatccaggac gaggtcgcgg agcagaaccc 700

 cctttcgctt aagtgaaaaa gatcgaatgg agctgttaga aatagcaaaa 750

 accaatgcag cgaaagctct aggaacaacc aacattgact tgccagctag 800

 tctcagaact gttccttcag ccaaagaaac aagccgtgga ataggtgtat 850

 caagtaatgg tgcaaagcct gaactgtcgg aaaaggtaac agaagatgga 900

 actcgaaatc ccaatggaaa acctacccag caaagaagca tagcttttag 950

 ctctaataat tctgtagcaa agccaataca aaaatcagct aaagctgcca 1000

 cagaagaggc atcttcaaga tcaccaaaaa tagatcagaa aaaaagtcca 1050

 tatggactgt ggatacctat ctaaaagaag aaaactgatg gctaagtttg 1100

 catgaaaact gcactttatt gcaagttagt gtttctagca ttatcccatc 1150

 cctttgagcc attcaggggt acttgtgcat ttaaaaacca acacaaaaag 1200

 atgtaaatac ttaacactca aatattaaca ttttaggttt ctcttgcaga 1250

 tatgagagat agcacagatg gaccaaaggt tatgcacagg tgggagtctt 1300

 ttgtatatag ttgtaaatat tgtcttggtt atgtaaaaat gaaatttttt 1350

 agacacagta attgaactgt attcctgttt tgtatattta ataaatttct 1400

 tgttttcatt cttaaaaaaa aaaaaaaaaa a 1431

<210> 1906
<211> 290
<212> PRT
<213> Homo sapien

<400> 1906
 Met Ser Asn Tyr Val Asn Asp Met Trp Pro Gly Ser Pro Gln Glu
   1               5                  10                  15

 Lys Asp Ser Pro Ser Thr Ser Arg Ser Gly Gly Ser Ser Arg Leu
                  20                  25                  30

 Ser Ser Arg Ser Arg Ser Arg Ser Phe Ser Arg Ser Ser Arg Ser
                  35                  40                  45

 His Ser Arg Val Ser Ser Arg Phe Ser Ser Arg Ser Arg Arg Ser
                  50                  55                  60

 Lys Ser Arg Ser Arg Ser Arg Arg Arg His Gln Arg Lys Tyr Arg
                  65                  70                  75

 Arg Tyr Ser Arg Ser Tyr Ser Arg Ser Arg Ser Arg Ser Arg Ser
                  80                  85                  90

 Arg Arg Tyr Arg Glu Arg Arg Tyr Gly Phe Thr Arg Arg Tyr Tyr
                  95                 100                 105

 Arg Ser Pro Ser Arg Tyr Arg Ser Arg Ser Arg Ser Arg Ser Arg
                 110                 115                 120

 Ser Arg Gly Arg Ser Tyr Cys Gly Arg Ala Tyr Ala Ile Ala Arg
                 125                 130                 135

 Gly Gln Arg Tyr Tyr Gly Phe Gly Arg Thr Val Tyr Pro Glu Glu
                 140                 145                 150

 His Ser Arg Trp Arg Asp Arg Ser Arg Thr Arg Ser Arg Ser Arg
                 155                 160                 165

 Thr Pro Phe Arg Leu Ser Glu Lys Asp Arg Met Glu Leu Leu Glu
                 170                 175                 180

 Ile Ala Lys Thr Asn Ala Ala Lys Ala Leu Gly Thr Thr Asn Ile
                 185                 190                 195

 Asp Leu Pro Ala Ser Leu Arg Thr Val Pro Ser Ala Lys Glu Thr
                 200                 205                 210

 Ser Arg Gly Ile Gly Val Ser Ser Asn Gly Ala Lys Pro Glu Leu
                 215                 220                 225

 Ser Glu Lys Val Thr Glu Asp Gly Thr Arg Asn Pro Asn Gly Lys
                 230                 235                 240

 Pro Thr Gln Gln Arg Ser Ile Ala Phe Ser Ser Asn Asn Ser Val
                 245                 250                 255

 Ala Lys Pro Ile Gln Lys Ser Ala Lys Ala Ala Thr Glu Glu Ala
                 260                 265                 270

 Ser Ser Arg Ser Pro Lys Ile Asp Gln Lys Lys Ser Pro Tyr Gly
                 275                 280                 285

 Leu Trp Ile Pro Ile
                 290

<210> 1907
<211> 3111
<212> DNA
<213> Homo sapien

<400> 1907
 gcgagttgtg tgagccgcca gtatggccgg gctatggcgg cgagcactgg 50

 ctacgtgcga ctgtggggag cggcgcggtg ctgggtgctg cggcggccga 100

 tgctggccgc cgccgggggg cgggttccca ctgcagcagg agcgtggttg 150

 ctccgaggcc agcggacctg cgacgcctct cctccttggg cactgtgggg 200

 ccgaggcccg gcaattgggg gccaatggcg ggggttttgg gaagcgagca 250

 gccgcggcgg aggcgcattc tcggggggcg aggacgcctc cgagggcggc 300

 gcggaggaag gagccggcgg cgcggggggc agcgcgggcg ccggggaagg 350

 cccggtcata acggcgctca cgcccatgac gatccccgat gtgtttccgc 400

 acctgccgct catcgccatc acccgcaacc cggtgttccc gcgctttatc 450

 aagattatcg aggttaaaaa taagaagttg gttgagctgc tgagaaggaa 500

 agttcgtctc gcccagcctt atgtcggcgt ctttctaaag agagatgaca 550

 gcaatgagtc ggatgtggtc gagagcctgg atgaaatcta ccacacgggg 600

 acgtttgccc agatccatga gatgcaggac cttggggaca agctgcgcat 650

 gatcgtcatg ggacacagaa gagtccatat cagcagacag ctggaggtgg 700

 agcccgagga gccggaggcg gagaacaagc acaagccccg caggaagtca 750

 aagcggggca agaaggaggc ggaggacgag ctgagcgcca ggcacccggc 800

 ggagctggcg atggagccca cccctgagct cccggctgag gtgctcatgg 850

 tggaggtaga gaacgttgtc cacgaggact tccaggtcac ggaggaggtg 900

 aaagccctga ctgcagagat cgtgaagacc atccgggaca tcattgcctt 950

 gaaccctctc tacagggagt cagtgctgca gatgatgcag gctggccagc 1000

 gggtggtgga caaccccatc tacctgagcg acatgggcgc cgcgctcacc 1050

 ggggccgagt cccatgagct gcaggacgtc ctggaagaga ccaatattcc 1100

 taagcggctg tacaaggccc tctccctgct gaagaaggaa tttgaactga 1150

 gcaagctgca gcagcgcctg gggcgggagg tggaggagaa gatcaagcag 1200

 acccaccgta agtacctgct gcaggagcag ctaaagatca tcaagaagga 1250

 gctgggcctg gagaaggacg acaaggatgc catcgaggag aagttccggg 1300

 agcgcctgaa ggagctcgtg gtccccaagc acgtcatgga tgttgtggac 1350

 gaggagctga gcaagctggg cctgctggac aaccactcct cggagttcaa 1400

 tgtcacccgc aactacctag actggctcac gtccatccct tggggcaagt 1450

 acagcaacga gaacctggac ctggcgcggg cacaggcagt gctggaggaa 1500

 gaccactacg gcatggagga cgtcaagaaa cgcatcctgg agttcattgc 1550

 cgttagccag ctccgcggct ccacccaggg caagatcctc tgcttctatg 1600

 gcccccctgg cgtgggtaag accagcattg ctcgctccat cgcccgcgcc 1650

 ctgaaccgag agtacttccg cttcagcgtc gggggcatga ctgacgtggc 1700

 tgagatcaag ggccacaggc ggacctacgt gggcgccatg cccgggaaga 1750

 tcatccagtg tttgaagaag accaagacgg agaaccccct gatcctcatc 1800

 gacgaggtgg acaagatcgg ccgaggctac cagggggacc cgtcgtcggc 1850

 actgctggag ctgctggacc cagagcagaa tgccaacttc ctggaccact 1900

 acctggacgt gcccgtggac ttgtccaagg tgctgttcat ctgcacggcc 1950

 aacgtcacgg acaccatccc cgagccgctg cgagaccgta tggagatgat 2000

 caacgtgtcg ggctacgtgg cccaggagaa gctggccatt gcggagcgct 2050

 acctggtgcc ccaggctcgc gccctgtgtg gcttggatga gagcaaggcc 2100

 aagctgtcat cggacgtgct gacgctgctc atcaagcagt actgccgcga 2150

 gagcggtgtc cgcaacctgc agaagcaagt ggagaaggtg ttacggaaat 2200

 cggcctacaa gattgtcagc ggcgaggccg agtccgtgga ggtgacgccc 2250

 gagaacctgc aggacttcgt ggggaagccc gtgttcaccg tggagcgcat 2300

 gtatgacgtg acaccgcccg gcgtggtcat ggggctggcc tggaccgcaa 2350

 tgggaggctc cacgctgttt gtggagacat ccctgagacg gccacaggac 2400

 aaggatgcca agggtgacaa ggatggcagc ctggaggtga caggccagct 2450

 gggggaggtg atgaaggaga gcgcccgcat agcctacacc ttcgccagag 2500

 ccttcctcat gcagcacgcc cccgccaatg actacctggt gacctcacac 2550

 atccacctgc atgtgcccga gggcgccacc cccaaggacg gcccaagcgc 2600

 aggctgcacc atcgtcacgg ccctgctgtc cctggccatg ggcaggcctg 2650

 tccggcagaa tctggccatg actggcgaag tctccctcac gggcaagatc 2700

 ctgcctgttg gtggcatcaa ggagaagacc attgcggcca agcgcgcagg 2750

 ggtgacgtgc atcgtcctgc cagccgagaa caagaaggac ttctacgacc 2800

 tggcagcctt catcaccgag ggcctggagg tgcacttcgt ggaacactac 2850

 cgggagatct tcgacatcgc cttcccggac gagcaggcag aggcgctggc 2900

 cgtggaacgg tgacggccac cccgggactg caggcggcgg atgtcaggcc 2950

 ctgtctgggc cagaactgag cgctgtgggg agcgcgcccg gacctggcag 3000

 tggagccacc gagcgagcag ctcggtccag tgacccagat cccagggacc 3050

 tcagtcggct taatcagagt gtggcataga agctatttaa tgattaaagt 3100

 catttgcagt a 3111

<210> 1908
<211> 959
<212> PRT
<213> Homo sapien

<400> 1908
 Met Ala Ala Ser Thr Gly Tyr Val Arg Leu Trp Gly Ala Ala Arg
   1               5                  10                  15

 Cys Trp Val Leu Arg Arg Pro Met Leu Ala Ala Ala Gly Gly Arg
                  20                  25                  30

 Val Pro Thr Ala Ala Gly Ala Trp Leu Leu Arg Gly Gln Arg Thr
                  35                  40                  45

 Cys Asp Ala Ser Pro Pro Trp Ala Leu Trp Gly Arg Gly Pro Ala
                  50                  55                  60

 Ile Gly Gly Gln Trp Arg Gly Phe Trp Glu Ala Ser Ser Arg Gly
                  65                  70                  75

 Gly Gly Ala Phe Ser Gly Gly Glu Asp Ala Ser Glu Gly Gly Ala
                  80                  85                  90

 Glu Glu Gly Ala Gly Gly Ala Gly Gly Ser Ala Gly Ala Gly Glu
                  95                 100                 105

 Gly Pro Val Ile Thr Ala Leu Thr Pro Met Thr Ile Pro Asp Val
                 110                 115                 120

 Phe Pro His Leu Pro Leu Ile Ala Ile Thr Arg Asn Pro Val Phe
                 125                 130                 135

 Pro Arg Phe Ile Lys Ile Ile Glu Val Lys Asn Lys Lys Leu Val
                 140                 145                 150

 Glu Leu Leu Arg Arg Lys Val Arg Leu Ala Gln Pro Tyr Val Gly
                 155                 160                 165

 Val Phe Leu Lys Arg Asp Asp Ser Asn Glu Ser Asp Val Val Glu
                 170                 175                 180

 Ser Leu Asp Glu Ile Tyr His Thr Gly Thr Phe Ala Gln Ile His
                 185                 190                 195

 Glu Met Gln Asp Leu Gly Asp Lys Leu Arg Met Ile Val Met Gly
                 200                 205                 210

 His Arg Arg Val His Ile Ser Arg Gln Leu Glu Val Glu Pro Glu
                 215                 220                 225

 Glu Pro Glu Ala Glu Asn Lys His Lys Pro Arg Arg Lys Ser Lys
                 230                 235                 240

 Arg Gly Lys Lys Glu Ala Glu Asp Glu Leu Ser Ala Arg His Pro
                 245                 250                 255

 Ala Glu Leu Ala Met Glu Pro Thr Pro Glu Leu Pro Ala Glu Val
                 260                 265                 270

 Leu Met Val Glu Val Glu Asn Val Val His Glu Asp Phe Gln Val
                 275                 280                 285

 Thr Glu Glu Val Lys Ala Leu Thr Ala Glu Ile Val Lys Thr Ile
                 290                 295                 300

 Arg Asp Ile Ile Ala Leu Asn Pro Leu Tyr Arg Glu Ser Val Leu
                 305                 310                 315

 Gln Met Met Gln Ala Gly Gln Arg Val Val Asp Asn Pro Ile Tyr
                 320                 325                 330

 Leu Ser Asp Met Gly Ala Ala Leu Thr Gly Ala Glu Ser His Glu
                 335                 340                 345

 Leu Gln Asp Val Leu Glu Glu Thr Asn Ile Pro Lys Arg Leu Tyr
                 350                 355                 360

 Lys Ala Leu Ser Leu Leu Lys Lys Glu Phe Glu Leu Ser Lys Leu
                 365                 370                 375

 Gln Gln Arg Leu Gly Arg Glu Val Glu Glu Lys Ile Lys Gln Thr
                 380                 385                 390

 His Arg Lys Tyr Leu Leu Gln Glu Gln Leu Lys Ile Ile Lys Lys
                 395                 400                 405

 Glu Leu Gly Leu Glu Lys Asp Asp Lys Asp Ala Ile Glu Glu Lys
                 410                 415                 420

 Phe Arg Glu Arg Leu Lys Glu Leu Val Val Pro Lys His Val Met
                 425                 430                 435

 Asp Val Val Asp Glu Glu Leu Ser Lys Leu Gly Leu Leu Asp Asn
                 440                 445                 450

 His Ser Ser Glu Phe Asn Val Thr Arg Asn Tyr Leu Asp Trp Leu
                 455                 460                 465

 Thr Ser Ile Pro Trp Gly Lys Tyr Ser Asn Glu Asn Leu Asp Leu
                 470                 475                 480

 Ala Arg Ala Gln Ala Val Leu Glu Glu Asp His Tyr Gly Met Glu
                 485                 490                 495

 Asp Val Lys Lys Arg Ile Leu Glu Phe Ile Ala Val Ser Gln Leu
                 500                 505                 510

 Arg Gly Ser Thr Gln Gly Lys Ile Leu Cys Phe Tyr Gly Pro Pro
                 515                 520                 525

 Gly Val Gly Lys Thr Ser Ile Ala Arg Ser Ile Ala Arg Ala Leu
                 530                 535                 540

 Asn Arg Glu Tyr Phe Arg Phe Ser Val Gly Gly Met Thr Asp Val
                 545                 550                 555

 Ala Glu Ile Lys Gly His Arg Arg Thr Tyr Val Gly Ala Met Pro
                 560                 565                 570

 Gly Lys Ile Ile Gln Cys Leu Lys Lys Thr Lys Thr Glu Asn Pro
                 575                 580                 585

 Leu Ile Leu Ile Asp Glu Val Asp Lys Ile Gly Arg Gly Tyr Gln
                 590                 595                 600

 Gly Asp Pro Ser Ser Ala Leu Leu Glu Leu Leu Asp Pro Glu Gln
                 605                 610                 615

 Asn Ala Asn Phe Leu Asp His Tyr Leu Asp Val Pro Val Asp Leu
                 620                 625                 630

 Ser Lys Val Leu Phe Ile Cys Thr Ala Asn Val Thr Asp Thr Ile
                 635                 640                 645

 Pro Glu Pro Leu Arg Asp Arg Met Glu Met Ile Asn Val Ser Gly
                 650                 655                 660

 Tyr Val Ala Gln Glu Lys Leu Ala Ile Ala Glu Arg Tyr Leu Val
                 665                 670                 675

 Pro Gln Ala Arg Ala Leu Cys Gly Leu Asp Glu Ser Lys Ala Lys
                 680                 685                 690

 Leu Ser Ser Asp Val Leu Thr Leu Leu Ile Lys Gln Tyr Cys Arg
                 695                 700                 705

 Glu Ser Gly Val Arg Asn Leu Gln Lys Gln Val Glu Lys Val Leu
                 710                 715                 720

 Arg Lys Ser Ala Tyr Lys Ile Val Ser Gly Glu Ala Glu Ser Val
                 725                 730                 735

 Glu Val Thr Pro Glu Asn Leu Gln Asp Phe Val Gly Lys Pro Val
                 740                 745                 750

 Phe Thr Val Glu Arg Met Tyr Asp Val Thr Pro Pro Gly Val Val
                 755                 760                 765

 Met Gly Leu Ala Trp Thr Ala Met Gly Gly Ser Thr Leu Phe Val
                 770                 775                 780

 Glu Thr Ser Leu Arg Arg Pro Gln Asp Lys Asp Ala Lys Gly Asp
                 785                 790                 795

 Lys Asp Gly Ser Leu Glu Val Thr Gly Gln Leu Gly Glu Val Met
                 800                 805                 810

 Lys Glu Ser Ala Arg Ile Ala Tyr Thr Phe Ala Arg Ala Phe Leu
                 815                 820                 825

 Met Gln His Ala Pro Ala Asn Asp Tyr Leu Val Thr Ser His Ile
                 830                 835                 840

 His Leu His Val Pro Glu Gly Ala Thr Pro Lys Asp Gly Pro Ser
                 845                 850                 855

 Ala Gly Cys Thr Ile Val Thr Ala Leu Leu Ser Leu Ala Met Gly
                 860                 865                 870

 Arg Pro Val Arg Gln Asn Leu Ala Met Thr Gly Glu Val Ser Leu
                 875                 880                 885

 Thr Gly Lys Ile Leu Pro Val Gly Gly Ile Lys Glu Lys Thr Ile
                 890                 895                 900

 Ala Ala Lys Arg Ala Gly Val Thr Cys Ile Val Leu Pro Ala Glu
                 905                 910                 915

 Asn Lys Lys Asp Phe Tyr Asp Leu Ala Ala Phe Ile Thr Glu Gly
                 920                 925                 930

 Leu Glu Val His Phe Val Glu His Tyr Arg Glu Ile Phe Asp Ile
                 935                 940                 945

 Ala Phe Pro Asp Glu Gln Ala Glu Ala Leu Ala Val Glu Arg
                 950                 955

<210> 1909
<211> 2932
<212> DNA
<213> Homo sapien

<400> 1909
 agagaggagc cgactcggca gggactgggg gaccgggccg agagtgcgag 50

 cgagcgaggg agggagtgag ggagcgtgcg agccagaagg ggaaaggcgg 100

 ccactcgtgc ctgagcgacc gcagagggga gtgggagcag tggggtaaag 150

 gagcgggggg cgggaataag aaaggccgag agaaggcgga cagaggctag 200

 tggtggtggt ggtggtaggg ggagaaggag gagctggagg agggcagggg 250

 ctgagggagt gagtgaagcg gacgcgcgag ggaggggagg gaagggaagg 300

 gaagggaagg gggggtcacg cgggggcgcg cgcgcgcacc gggagcgcgc 350

 tcggaggcga gtggaactgg atcgggtttg ctgccagcgg cgtgagcttc 400

 ggccgccatt ttacaacagc tccactcgcg ccggacacag ggagcagcga 450

 gcacgcgttt cccgcaaccc gataccatcg gacaggattt ctccgcctca 500

 gcccaacggg gagatctctg gaaacatggc tacagaacat gttaatggaa 550

 atggtactga agagcccatg gatactactt ctgcagttat ccattcagaa 600

 aattttcaga cattgcttga tgctggttta ccacagaaag ttgctgaaaa 650

 actagatgaa atttacgttg cagggctagt tgcacatagt gatttagatg 700

 aaagagctat tgaagcttta aaagaattca atgaagacgg tgcattggca 750

 gttcttcaac agtttaaaga cagtgatctc tctcatgttc agaacaaaag 800

 tgccttttta tgtggagtca tgaagactta caggcagaga gaaaaacaag 850

 ggaccaaagt agcagattct agtaaaggac cagatgaggc aaaaattaag 900

 gcactcttgg aaagaacagg ctacacactt gatgtgacca ctggacagag 950

 gaagtatgga ggaccacctc cagattccgt ttattcaggt cagcagcctt 1000

 ctgttggcac tgagatattt gtgggaaaga tcccaagaga tctatttgag 1050

 gatgaacttg ttccattatt tgagaaagct ggacctatat gggatcttcg 1100

 tctaatgatg gatccactca ctggtctcaa tagaggttat gcgtttgtca 1150

 ctttttgtac aaaagaagca gctcaggagg ctgttaaact gtataataat 1200

 catgaaattc gttctggaaa acatattggt gtctgcatct cagttgccaa 1250

 caataggctt tttgtgggct ctattcctaa gagtaaaacc aaggaacaga 1300

 ttcttgaaga atttagcaaa gtaacagagg gtcttacaga cgtcatttta 1350

 taccaccaac cggatgacaa gaaaaaaaac aggagctttt gctttcttga 1400

 atatgaagat cacaaaacag ctgcccaggc aaggcgtagg ttaatgagtg 1450

 gtaaagtcaa ggtctggggg aatgttggaa ctgttgaatg ggctgatcct 1500

 atagaagatc ctgatcctga ggttatggca aaggtaaaag tgctgtttgt 1550

 acgcaacctt gccaatactg taacagaaga gattttagaa aaggcattta 1600

 gtcagtttgg gaaactggaa cgagtgaaga agttaaaaga ttatgcgttc 1650

 attcattttg atgagcgaga tggtgctgtc aaggctatgg aagaaatgaa 1700

 tggcaaagac ttggagggag aaaatattga aattgttttt gccaagccac 1750

 cagatcagaa aaggaaagaa agaaaagctc agaggcaagc agcaaaaaat 1800

 caaatgtatg acgattacta ctattatggt ccacctcata tgccccctcc 1850

 aacaagaggt cgagggcgtg gaggtagagg tggttatgga tatcctccag 1900

 attattatgg atatgaagat tattatgatt attatggtta tgattaccat 1950

 aactatcgtg gtggatatga agatccatac tatggttatg aagattttca 2000

 agttggagct agaggaaggg gtggtagagg agcaaggggt gctgctccat 2050

 ccagaggtcg tggggctgct cctccccgcg gtagagccgg ttattcacag 2100

 agaggaggtc ctggatcagc aagaggcgtt cgaggtgcga gaggaggtgc 2150

 ccaacaacaa agaggccgcg gggtacgtgg tgcgaggggt ggccgcggtg 2200

 gaaatgtagg aggaaagcgc aaagctgatg ggtacaacca gccagattcc 2250

 aagcggcgcc agaccaataa tcagaactgg ggctcccaac ccattgctca 2300

 gcaaccgctc caaggtggtg atcattctgg taactatggt tacaaatctg 2350

 aaaaccagga gttttatcag gatacttttg ggcaacagtg gaagtagaaa 2400

 cagtagggcc tctgtaaaat tggagactga taggttgatc agaaactcac 2450

 cctaaatctg aacgggtgcc gctataattt gtgacatctg gcaagatttc 2500

 cctttatgta tatattttaa caatccgctt ggacacgaac aaagccacac 2550

 ttctaactgc ttctggcgaa ctgattttat ttttaatttt tttcaataaa 2600

 gatattctta gatactgaaa gaaatagtta atgagtttgc atttgtgctt 2650

 gagaaaattt ggctcaagtc catttggctg tagtgtcaac gatgtttcca 2700

 gtagtgttta gatttggtgt cttcaaaggt agttgattaa aaccaagtgt 2750

 gtctttaata tcttgtatca gaataacttt gtatgttacc aacttaaatt 2800

 gctagaataa ggtaaattga tacacaactg ctatttttaa tttagaactt 2850

 tgacctaatt tgggttttca aaaccatttt ggctacttgt attctttatg 2900

 ctgttgttta tttcaataaa aaattcacac ct 2932

<210> 1910
<211> 623
<212> PRT
<213> Homo sapien

<400> 1910
 Met Ala Thr Glu His Val Asn Gly Asn Gly Thr Glu Glu Pro Met
   1               5                  10                  15

 Asp Thr Thr Ser Ala Val Ile His Ser Glu Asn Phe Gln Thr Leu
                  20                  25                  30

 Leu Asp Ala Gly Leu Pro Gln Lys Val Ala Glu Lys Leu Asp Glu
                  35                  40                  45

 Ile Tyr Val Ala Gly Leu Val Ala His Ser Asp Leu Asp Glu Arg
                  50                  55                  60

 Ala Ile Glu Ala Leu Lys Glu Phe Asn Glu Asp Gly Ala Leu Ala
                  65                  70                  75

 Val Leu Gln Gln Phe Lys Asp Ser Asp Leu Ser His Val Gln Asn
                  80                  85                  90

 Lys Ser Ala Phe Leu Cys Gly Val Met Lys Thr Tyr Arg Gln Arg
                  95                 100                 105

 Glu Lys Gln Gly Thr Lys Val Ala Asp Ser Ser Lys Gly Pro Asp
                 110                 115                 120

 Glu Ala Lys Ile Lys Ala Leu Leu Glu Arg Thr Gly Tyr Thr Leu
                 125                 130                 135

 Asp Val Thr Thr Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro Asp
                 140                 145                 150

 Ser Val Tyr Ser Gly Gln Gln Pro Ser Val Gly Thr Glu Ile Phe
                 155                 160                 165

 Val Gly Lys Ile Pro Arg Asp Leu Phe Glu Asp Glu Leu Val Pro
                 170                 175                 180

 Leu Phe Glu Lys Ala Gly Pro Ile Trp Asp Leu Arg Leu Met Met
                 185                 190                 195

 Asp Pro Leu Thr Gly Leu Asn Arg Gly Tyr Ala Phe Val Thr Phe
                 200                 205                 210

 Cys Thr Lys Glu Ala Ala Gln Glu Ala Val Lys Leu Tyr Asn Asn
                 215                 220                 225

 His Glu Ile Arg Ser Gly Lys His Ile Gly Val Cys Ile Ser Val
                 230                 235                 240

 Ala Asn Asn Arg Leu Phe Val Gly Ser Ile Pro Lys Ser Lys Thr
                 245                 250                 255

 Lys Glu Gln Ile Leu Glu Glu Phe Ser Lys Val Thr Glu Gly Leu
                 260                 265                 270

 Thr Asp Val Ile Leu Tyr His Gln Pro Asp Asp Lys Lys Lys Asn
                 275                 280                 285

 Arg Ser Phe Cys Phe Leu Glu Tyr Glu Asp His Lys Thr Ala Ala
                 290                 295                 300

 Gln Ala Arg Arg Arg Leu Met Ser Gly Lys Val Lys Val Trp Gly
                 305                 310                 315

 Asn Val Gly Thr Val Glu Trp Ala Asp Pro Ile Glu Asp Pro Asp
                 320                 325                 330

 Pro Glu Val Met Ala Lys Val Lys Val Leu Phe Val Arg Asn Leu
                 335                 340                 345

 Ala Asn Thr Val Thr Glu Glu Ile Leu Glu Lys Ala Phe Ser Gln
                 350                 355                 360

 Phe Gly Lys Leu Glu Arg Val Lys Lys Leu Lys Asp Tyr Ala Phe
                 365                 370                 375

 Ile His Phe Asp Glu Arg Asp Gly Ala Val Lys Ala Met Glu Glu
                 380                 385                 390

 Met Asn Gly Lys Asp Leu Glu Gly Glu Asn Ile Glu Ile Val Phe
                 395                 400                 405

 Ala Lys Pro Pro Asp Gln Lys Arg Lys Glu Arg Lys Ala Gln Arg
                 410                 415                 420

 Gln Ala Ala Lys Asn Gln Met Tyr Asp Asp Tyr Tyr Tyr Tyr Gly
                 425                 430                 435

 Pro Pro His Met Pro Pro Pro Thr Arg Gly Arg Gly Arg Gly Gly
                 440                 445                 450

 Arg Gly Gly Tyr Gly Tyr Pro Pro Asp Tyr Tyr Gly Tyr Glu Asp
                 455                 460                 465

 Tyr Tyr Asp Tyr Tyr Gly Tyr Asp Tyr His Asn Tyr Arg Gly Gly
                 470                 475                 480

 Tyr Glu Asp Pro Tyr Tyr Gly Tyr Glu Asp Phe Gln Val Gly Ala
                 485                 490                 495

 Arg Gly Arg Gly Gly Arg Gly Ala Arg Gly Ala Ala Pro Ser Arg
                 500                 505                 510

 Gly Arg Gly Ala Ala Pro Pro Arg Gly Arg Ala Gly Tyr Ser Gln
                 515                 520                 525

 Arg Gly Gly Pro Gly Ser Ala Arg Gly Val Arg Gly Ala Arg Gly
                 530                 535                 540

 Gly Ala Gln Gln Gln Arg Gly Arg Gly Val Arg Gly Ala Arg Gly
                 545                 550                 555

 Gly Arg Gly Gly Asn Val Gly Gly Lys Arg Lys Ala Asp Gly Tyr
                 560                 565                 570

 Asn Gln Pro Asp Ser Lys Arg Arg Gln Thr Asn Asn Gln Asn Trp
                 575                 580                 585

 Gly Ser Gln Pro Ile Ala Gln Gln Pro Leu Gln Gly Gly Asp His
                 590                 595                 600

 Ser Gly Asn Tyr Gly Tyr Lys Ser Glu Asn Gln Glu Phe Tyr Gln
                 605                 610                 615

 Asp Thr Phe Gly Gln Gln Trp Lys
                 620

<210> 1911
<211> 721
<212> DNA
<213> Homo sapien

<400> 1911
 gccaaaagga aaattatgct ggggcaaagt ttagtgatcc accttctcct 50

 agtgttcttc caaagcctcc tagtcactgg atgggaagca ctgttgaaaa 100

 ttccaaccaa aacagggagc tgatggcagt acacttaaaa acgctcctca 150

 aagttcaaac ttagatttca gatttcagta tgtgtgtaaa acataatttt 200

 tcccatatcc ctggactctt gagaaaattg gtacagaaat ggaaatttgc 250

 cttgttgcaa catacaattg caaaagatga gtttaaaaaa ttacatacaa 300

 acagcttgta ttatatttta tattttgtaa atactgtata ccatgtatta 350

 tgtgtatatt gttcatactt gagaggtata ttatagtttt gttatgaaag 400

 tatgtatttt gccctgccca cattgcaggt gttttgtata tatacaatgg 450

 ataaatttta agtgtgtgct aaggcacatg gaagaccgat tttatttgca 500

 caaggtactg agattttttt caagaaacag ctgtcaaatc tcaaggtgaa 550

 gaactaaatg tgaacagttt actaatgcac tactgaagtt aaatctgtgg 600

 ccaatcaatg taagcattgg ggttggttct ctaaattgat ttgaatctga 650

 aatactgaca actcctattc ccattttgct aaactcaatt ctggtttgga 700

 tatatccatt ccagcttaat g 721

<210> 1912
<211> 68
<212> PRT
<213> Homo sapien

<400> 1912
 Met Cys Val Lys His Asn Phe Ser His Ile Pro Gly Leu Leu Arg
   1               5                  10                  15

 Lys Leu Val Gln Lys Trp Lys Phe Ala Leu Leu Gln His Thr Ile
                  20                  25                  30

 Ala Lys Asp Glu Phe Lys Lys Leu His Thr Asn Ser Leu Tyr Tyr
                  35                  40                  45

 Ile Leu Tyr Phe Val Asn Thr Val Tyr His Val Leu Cys Val Tyr
                  50                  55                  60

 Cys Ser Tyr Leu Arg Gly Ile Leu
                  65

<210> 1913
<211> 3150
<212> DNA
<213> Homo sapien

<400> 1913
 caaaacctcc accaccggca gcatcctgaa tcttaacctg gatcgaagca 50

 aagctgagat ggatttgaag gagctgagcg agtcggtcca gcaacagtcc 100

 acccctgttc ctctcatctc tcccaagcgc cagattcgta gcaggttcca 150

 gctgaatctt gacaagacca tagagagttg caaagcacaa ttaggcataa 200

 atgaaatctc ggaagatgtc tatacggccg tagagcacag cgattcggag 250

 gattctgaga agtcagatag tagcgatagt gagtatatca gtgatgatga 300

 gcagaagtct aagaacgagc cagaagacac agaggacaaa gaaggttgtc 350

 agatggacaa agagccatct gctgttaaaa aaaagcccaa gcctacaaac 400

 ccagtggaga ttaaagagga gctgaaaagc acgtcaccag ccagcgagaa 450

 ggcagaccct ggagcagtca aggacaaggc cagccctgag cctgagaagg 500

 acttttccga aaaggcaaaa ccttcacctc accccataaa ggataaactg 550

 aagggaaaag atgagacgga ttccccaaca gtccatttgg gcctggactc 600

 tgattcagag agcgaacttg tcatagattt aggagaagac cattctgggc 650

 gggagggtcg aaaaaataag aaggaaccca aagaaccatc tcccaaacag 700

 gatgttgtag gtaaaacacc accatccacg acggtgggca gccattctcc 750

 cccggaaaca ccggtgctca cccgctcttc cgcccaaact tccgcggctg 800

 gcgccacagc caccaccagc acgtcctcca cggtcaccgt cacggccccg 850

 gcccccgccg ccacaggaag cccagtgaaa aagcagaggc cgcttttacc 900

 gaaggagact gccccggccg tgcagcgggt cgtgtggaac tcatcaagtg 950

 tccagcagaa ggagatcaca cagagcccat ccacgtccac catcaccctg 1000

 gtgaccagca cacagtcatc gcccctggtc accagctcgg ggtccatgag 1050

 cacccttgtg tcctcagtca acgctgacct gcccatcgcc actgcctcag 1100

 ctgatgtcgc cgctgatatt gccaagtaca ctagcaaaat gatggatgca 1150

 ataaaaggaa caatgacaga aatatacaac gatctttcta aaaacactac 1200

 tggaagcaca atagctgaga ttcgcaggct gaggatcgag atagagaagc 1250

 tccagtggct gcaccagcaa gagctctccg aaatgaaaca caacttagag 1300

 ctgaccatgg cggagatgcg gcagagcctg gagcaggagc gggaccggct 1350

 catcgccgag gtgaagaagc agctggagtt ggagaagcag caggcggtgg 1400

 atgagaccaa gaagaagcag tggtgcgcca actgcaagaa ggaggccatc 1450

 ttttactgct gttggaacac cagctactgt gactacccct gccagcaagc 1500

 ccactggcct gagcacatga agtcctgcac ccagtcagct actgctcctc 1550

 agcaggaagc ggatgctgag gtgaacacag aaacactaaa taagtcctcc 1600

 caggggagct cctcgagcac acaatcagca ccttcagaaa cggccagcgc 1650

 ctccaaagag aaggagacgt cagctgagaa aagcaaggag agtggctcga 1700

 cccttgacct ttctggctcc agagagacgc cctcctccat tctcttaggc 1750

 tccaaccaag gctctgacca ttcccggagt aataaatcca gttggagcag 1800

 cagtgatgag aagaggggat cgacacgttc cgatcacaac accagtacca 1850

 gcacgaagag cctcctcccg aaagagtctc ggctggacac cttctgggac 1900

 tagcagtgaa tcgggacaca aaccacccac cccattggga gaaaaaccca 1950

 gacgccagga aaagaagaaa caacaaaggc aggagaacag ccactttcag 2000

 acttgaaaat gacaaaaccc tcagttgagc ctgagccccc ggcgcggggg 2050

 ctgctacact acaggacacc cagcatcggc tttgactgca gactgttcac 2100

 ccacacgagc cctgtgcttt tggtgtaata aatgtacaat ttgtggatgt 2150

 cattgaatct agaggacttt ccccttttta tatttgtatt aactttaact 2200

 tattaaaaaa aaaaaaagaa aaagaaaaac gatttaaaaa aaaaaaaaaa 2250

 agcaaccaac cccaacaaca aaaaagaatg ttttggtatt ggagaaggga 2300

 tggtcagtta gcctgtctgt cacacgacgg aatggatact gggcccgggg 2350

 accactttca tactcacgtc ctcatccttg gatacccagg ggagggcgaa 2400

 ccgttttcgc tcgtgtgtct gtacgcagca tgttgggatc gggagtttcg 2450

 gcacagacta tcccatcaag ccgttggctc ctttcagcta ctacgttacc 2500

 acgttcctaa aacgcaagct ctccggacca gacggacaca gggagaagct 2550

 agtttctttc atgtgattga aatgatgact ctactcctaa aagggaaaaa 2600

 acaatatcct tgtttacaga agagaaacaa acaagcccca ctcagctcag 2650

 tcacaggaga gaacacagaa agtcttagga tcatgaactc tgaaaaaaag 2700

 agaaacctta tctttgcttt gtggttcctt taaacacact cacacacact 2750

 tggtcagaga tgctgtgctt cttggaagca aggactcaaa ggcaaggtgc 2800

 acgcagagga cgtttgagtc tgggatgaag catgtacgta ttatttatat 2850

 gatggaattt cacgttttta tgtaagcatg aaacacaggc agtatgagag 2900

 aaagcaaggc ccgtcatgct gtccgtacac tacgtatgct tgtagagcca 2950

 ttttgtatgt tgtgtaaaac aaaaagcatt gatgaaaaag caaaaggtga 3000

 tgtatgtata tgagaaaatt aattgtacga tatcattcca gtacgttttg 3050

 ttgtacattt tagtcttgtt tactttctct tcattgttaa gaggatgcga 3100

 actgtacagt ttccagctag ttacccatat tagagaagaa ataagagagt 3150

<210> 1914
<211> 614
<212> PRT
<213> Homo sapien

<400> 1914
 Met Asp Leu Lys Glu Leu Ser Glu Ser Val Gln Gln Gln Ser Thr
   1               5                  10                  15

 Pro Val Pro Leu Ile Ser Pro Lys Arg Gln Ile Arg Ser Arg Phe
                  20                  25                  30

 Gln Leu Asn Leu Asp Lys Thr Ile Glu Ser Cys Lys Ala Gln Leu
                  35                  40                  45

 Gly Ile Asn Glu Ile Ser Glu Asp Val Tyr Thr Ala Val Glu His
                  50                  55                  60

 Ser Asp Ser Glu Asp Ser Glu Lys Ser Asp Ser Ser Asp Ser Glu
                  65                  70                  75

 Tyr Ile Ser Asp Asp Glu Gln Lys Ser Lys Asn Glu Pro Glu Asp
                  80                  85                  90

 Thr Glu Asp Lys Glu Gly Cys Gln Met Asp Lys Glu Pro Ser Ala
                  95                 100                 105

 Val Lys Lys Lys Pro Lys Pro Thr Asn Pro Val Glu Ile Lys Glu
                 110                 115                 120

 Glu Leu Lys Ser Thr Ser Pro Ala Ser Glu Lys Ala Asp Pro Gly
                 125                 130                 135

 Ala Val Lys Asp Lys Ala Ser Pro Glu Pro Glu Lys Asp Phe Ser
                 140                 145                 150

 Glu Lys Ala Lys Pro Ser Pro His Pro Ile Lys Asp Lys Leu Lys
                 155                 160                 165

 Gly Lys Asp Glu Thr Asp Ser Pro Thr Val His Leu Gly Leu Asp
                 170                 175                 180

 Ser Asp Ser Glu Ser Glu Leu Val Ile Asp Leu Gly Glu Asp His
                 185                 190                 195

 Ser Gly Arg Glu Gly Arg Lys Asn Lys Lys Glu Pro Lys Glu Pro
                 200                 205                 210

 Ser Pro Lys Gln Asp Val Val Gly Lys Thr Pro Pro Ser Thr Thr
                 215                 220                 225

 Val Gly Ser His Ser Pro Pro Glu Thr Pro Val Leu Thr Arg Ser
                 230                 235                 240

 Ser Ala Gln Thr Ser Ala Ala Gly Ala Thr Ala Thr Thr Ser Thr
                 245                 250                 255

 Ser Ser Thr Val Thr Val Thr Ala Pro Ala Pro Ala Ala Thr Gly
                 260                 265                 270

 Ser Pro Val Lys Lys Gln Arg Pro Leu Leu Pro Lys Glu Thr Ala
                 275                 280                 285

 Pro Ala Val Gln Arg Val Val Trp Asn Ser Ser Ser Val Gln Gln
                 290                 295                 300

 Lys Glu Ile Thr Gln Ser Pro Ser Thr Ser Thr Ile Thr Leu Val
                 305                 310                 315

 Thr Ser Thr Gln Ser Ser Pro Leu Val Thr Ser Ser Gly Ser Met
                 320                 325                 330

 Ser Thr Leu Val Ser Ser Val Asn Ala Asp Leu Pro Ile Ala Thr
                 335                 340                 345

 Ala Ser Ala Asp Val Ala Ala Asp Ile Ala Lys Tyr Thr Ser Lys
                 350                 355                 360

 Met Met Asp Ala Ile Lys Gly Thr Met Thr Glu Ile Tyr Asn Asp
                 365                 370                 375

 Leu Ser Lys Asn Thr Thr Gly Ser Thr Ile Ala Glu Ile Arg Arg
                 380                 385                 390

 Leu Arg Ile Glu Ile Glu Lys Leu Gln Trp Leu His Gln Gln Glu
                 395                 400                 405

 Leu Ser Glu Met Lys His Asn Leu Glu Leu Thr Met Ala Glu Met
                 410                 415                 420

 Arg Gln Ser Leu Glu Gln Glu Arg Asp Arg Leu Ile Ala Glu Val
                 425                 430                 435

 Lys Lys Gln Leu Glu Leu Glu Lys Gln Gln Ala Val Asp Glu Thr
                 440                 445                 450

 Lys Lys Lys Gln Trp Cys Ala Asn Cys Lys Lys Glu Ala Ile Phe
                 455                 460                 465

 Tyr Cys Cys Trp Asn Thr Ser Tyr Cys Asp Tyr Pro Cys Gln Gln
                 470                 475                 480

 Ala His Trp Pro Glu His Met Lys Ser Cys Thr Gln Ser Ala Thr
                 485                 490                 495

 Ala Pro Gln Gln Glu Ala Asp Ala Glu Val Asn Thr Glu Thr Leu
                 500                 505                 510

 Asn Lys Ser Ser Gln Gly Ser Ser Ser Ser Thr Gln Ser Ala Pro
                 515                 520                 525

 Ser Glu Thr Ala Ser Ala Ser Lys Glu Lys Glu Thr Ser Ala Glu
                 530                 535                 540

 Lys Ser Lys Glu Ser Gly Ser Thr Leu Asp Leu Ser Gly Ser Arg
                 545                 550                 555

 Glu Thr Pro Ser Ser Ile Leu Leu Gly Ser Asn Gln Gly Ser Asp
                 560                 565                 570

 His Ser Arg Ser Asn Lys Ser Ser Trp Ser Ser Ser Asp Glu Lys
                 575                 580                 585

 Arg Gly Ser Thr Arg Ser Asp His Asn Thr Ser Thr Ser Thr Lys
                 590                 595                 600

 Ser Leu Leu Pro Lys Glu Ser Arg Leu Asp Thr Phe Trp Asp
                 605                 610

<210> 1915
<211> 7530
<212> DNA
<213> Homo sapien

<400> 1915
 tggtcttgaa ctcctgacct tgtgatccgc tcgcctcagc ctcccaaagt 50

 gctgggatta caggcatgag ccaccgtgcc tgtcctagaa ccactggtaa 100

 ctcttaactg gttctaagaa cggaagcatc tgggctggat ggaatttagc 150

 atcaagcaga gtcccctttc tgttcagagt gttgtaaagt gcataaagat 200

 gaagcaggca ccagaaatcc tcggcagtgc caacgggaag actccgagct 250

 gcgaggtgaa ccgcgagtgt tctgtgttcc tcagcaaagc ccagctctcc 300

 agtagcctgc aggagggggt catgcagaag tttaacggcc acgacgccct 350

 gccctttatt ccagccgaca agctgaaaga tcttacttcc cgggtgttta 400

 atggagaacc cggcgcacac gatgccaaac tgcgttttga gtcccaggaa 450

 atgaaaggga ttgggacacc ccctaacact acccctatca aaaatggctc 500

 tccagaaatt aagctgaaaa tcaccaaaac atacatgaat gggaagcctc 550

 tctttgaatc ttccatttgt ggtgacagtg ctgctgatgt gtctcagtca 600

 gaagaaaatg gacaaaaacc agaaaacaag gcgagaagga acaggaagag 650

 gagcataaaa tatgactcct tgctggagca gggccttgtc gaagcagctc 700

 ttgtgtctaa gatctcaagt ccttcagata aaaagattcc agctaagaaa 750

 gagtcttgtc caaacactgg aagagacaaa gaccacctgt tgaaatacaa 800

 cgttggtgat ttggtgtggt ccaaagtgtc gggttaccct tggtggcctt 850

 gcatggtttc tgcagatcca ctccttcaca gctataccaa acttaaaggt 900

 cagaaaaaga gtgcacgcca gtatcacgta cagttctttg gtgacgcccc 950

 agaaagagct tggatatttg agaagagcct cgtagctttt gaaggagaag 1000

 gacagtttga aaaattatgc caggaaagtg ccaagcaggc acccacgaaa 1050

 gctgagaaaa ttaagctatt gaaaccaatt tcagggaaat tgagggccca 1100

 gtgggaaatg ggcattgttc aagcagaaga agctgcaagc atgtcagtgg 1150

 aggagcggaa agccaagttc acctttctct atgtggggga ccagcttcat 1200

 ctcaaccctc aagtagccaa ggaggctggc attgctgcag agtctttggg 1250

 agaaatggca gaatcctcag gagtcagtga agaagctgct gaaaacccca 1300

 agtctgtgag agaagagtgc attcccatga agagaaggcg gagggccaaa 1350

 ctgtgtagct ctgcagagac cctggagagt caccccgaca tagggaagag 1400

 tactcctcaa aagacggcag aggctgaccc cagaagagga gtagggtctc 1450

 ctcctgggag gaagaagacc acagtctcca tgccacgaag caggaaggga 1500

 gatgcagcat cccagttttt ggtcttctgt caaaaacaca gggatgaggt 1550

 ggtagctgag cacccagatg cttcaggtga ggagattgaa gagctgctca 1600

 ggtcacagtg gagtctgctg agtgagaagc agagagcacg ctacaacacc 1650

 aagtttgccc tggtggcccc tgtccaggct gaagaagact ctggtaatgt 1700

 aaatgggaaa aaaagaaacc acacaaagag gatacaggac cctacagaag 1750

 atgctgaagc tgaggacaca cccaggaaaa gactcaggac ggacaagcac 1800

 agtcttcgga agagagacac aatcactgac aaaacggcca gaacaagctc 1850

 ttacaaggcc atggaggcag cctcctcgct caagagccag gcagcaacga 1900

 aaaatctgtc tgatgcatgt aaaccactga agaagcgaaa tcgggcttcc 1950

 acggcagcat cttcagctct tgggtttagc aaaagttcat ctccttctgc 2000

 atccttaact gagaatgagg tctcggacag cccgggagac gagccctcgg 2050

 agtccccata cgaaagtgca gacgaaacac aaactgaagt atctgtctca 2100

 tccaaaaagt ctgagcgagg agtgactgcc aaaaaggagt atgtgtgcca 2150

 gctgtgtgag aagccgggca gcctcctgct ctgtgaagga ccctgctgcg 2200

 gagctttcca cctcgcctgc cttgggcttt cccggaggcc agaagggagg 2250

 ttcacctgca gcgagtgtgc ctcagggatt cactcatgtt tcgtgtgtaa 2300

 agagagcaag acagatgtta agcgctgtgt ggtaactcag tgtggaaaat 2350

 tttaccatga ggcttgtgtg aaaaaatacc ctctgactgt atttgagagc 2400

 cgaggtttcc gctgccccct ccacagctgt gtgagctgcc atgcttccaa 2450

 cccttcaaac ccaaggccgt caaaaggtaa aatgatgcgg tgtgtccgct 2500

 gccccgttgc ctatcacagc ggggatgctt gtctggcagc aggatgctca 2550

 gtgatcgcct ccaacagcat catctgcact gcccacttca ctgctcggaa 2600

 ggggaagcga caccacgccc acgtcaacgt gagctggtgc ttcgtgtgct 2650

 ccaaaggggg gagccttctg tgctgtgagt cctgcccagc ggccttccac 2700

 cctgactgcc tgaacatcga gatgcctgac ggcagctggt tctgcaatga 2750

 ctgcagggct gggaagaagc tgcacttcca ggatatcatt tgggtgaaac 2800

 ttgggaacta cagatggtgg ccggcagaag tttgccatcc caaaaatgtt 2850

 cccccaaata ttcagaaaat gaagcacgag attggagaat tccctgtgtt 2900

 tttctttggg tctaaagatt attactggac gcatcaggcg cgagtgttcc 2950

 cgtacatgga gggggaccgg ggcagccgct accagggggt cagagggatc 3000

 ggaagagtct tcaaaaacgc actgcaagaa gctgaagctc gttttcgtga 3050

 aattaagctt cagagggaag cccgagaaac acaggagagc gagcgcaagc 3100

 ccccaccata caagcacatc aaggtgaata agccttacgg gaaagtccag 3150

 atctacacag cggatatttc agaaatccct aagtgcaact gcaagcccac 3200

 agatgagaat ccttgtggct ttgattcgga gtgtctgaac aggatgctga 3250

 tgtttgagtg ccacccgcag gtgtgtcccg cgggcgagtt ctgccagaac 3300

 cagtgcttca ccaagcgcca gtacccagag accaagatca tcaagacaga 3350

 tggcaaaggg tggggcctgg tcgccaagag ggacatcaga aagggagaat 3400

 ttgttaacga gtacgttggg gagctgatcg acgaggagga gtgcatggcg 3450

 agaatcaagc acgcacacga gaacgacatc acccacttct acatgctcac 3500

 tatagacaag gaccgtataa tagacgctgg ccccaaagga aactactctc 3550

 gatttatgaa tcacagctgc cagcccaact gtgagaccct caagtggaca 3600

 gtgaatgggg acactcgtgt gggcctgttt gccgtctgtg acattcctgc 3650

 agggacggag ctgactttta actacaacct cgattgtctg ggcaatgaaa 3700

 aaacggtctg ccggtgtgga gcctccaatt gcagtggatt cctcggggat 3750

 agaccaaaga cctcgacgac cctttcatca gaggaaaagg gcaaaaagac 3800

 caagaagaaa acgaggcggc gcagagcaaa aggggaaggg aagaggcagt 3850

 cagaggacga gtgcttccgc tgcggtgatg gcgggcagct ggtgctgtgt 3900

 gaccgcaagt tctgcaccaa ggcctaccac ctgtcctgcc tgggccttgg 3950

 caagcggccc ttcgggaagt gggaatgtcc ttggcatcat tgtgacgtgt 4000

 gtggcaaacc ttcgacttca ttttgccacc tctgccccaa ttcgttctgt 4050

 aaggagcacc aggacgggac agccttcagc tgcaccccgg acgggcggtc 4100

 ctactgctgt gagcatgact taggggcggc atcggtcaga agcaccaaga 4150

 ctgagaagcc ccccccagag ccagggaagc cgaaggggaa gaggcggcgg 4200

 cggaggggct ggcggagagt cacagagggc aaatagcgcc aggcggccgc 4250

 ttggccggat ccaggggcgg tgcagggcgg ccggccctgc ctgcgggaga 4300

 gggcgagcat gaactggccc ggaggaccca gctcgagccg ccaggacaca 4350

 gacgtacagg cctcctcggg agggagcgcc tccccaccac tgagccatcc 4400

 tcagcagcgt ccgctgcgtc tgcactgatg accgtctgag cccagctcag 4450

 cgttcctgga caaacagcct cactcctcag cgttaccgcc acacttgaat 4500

 ttctccgaat gtcaaggttc cctcccactc tattttttta ggttaaagtt 4550

 aattggcata tggaatgttt taatctcctc tgaaatgtgt agcgtaggct 4600

 tttcccaagg gtcgctagaa actcgtcttc gcgttgcccc ctttctggct 4650

 ctcagcgccg tcgccactcg ggagaggctg ggtgaggccc gtgtgaggac 4700

 tgaccctgga ttcctcgaaa ctgccattgt gatcattact ctgctctttg 4750

 gaaatggctg tatcattttt ttgtactaat gtgaattgtt cctcagaaac 4800

 gcttcttttc catcctagtg agaagctggc cctgcaggtg gtggcagcaa 4850

 tggtgttgta agatttcctc ccgtagtttt ttctcctcat ggatttgaat 4900

 gaaatgccaa taacacgtcc actttcaacg tgtagtttac gcggagcact 4950

 ttcgaggcct ggccgggttg ggcctacttc tcacctgggc ctatcttctg 5000

 aactcgctag gttcttatca acatttgggg gataactttg tatatttttt 5050

 tcatttggct tttctttacc agtttctgat ttttattctc aatatatttt 5100

 tgctaaacct atttcacaaa tcaccaccga ctgaagtgtg tgtttactga 5150

 tgcggccctg agctccatgg cgaaaggagt gactttgcag ggcgtgagac 5200

 cgcagtctgc ttagagcaca ggaagtgaca acttagggag ccccgtaggg 5250

 cgctgcaggc cccggggacc ccagcacgtg ggtctaaaga gagacggagt 5300

 ctagctctcc tgccacccag agtggcttcc atctcagcac tctgtgggtc 5350

 tggtgatgga agatgcagtc tctgctgatc acatgtgccc tctgccaggg 5400

 cacctactga gaggtgcggt cctgggggtg gaggcctgcc tggcaggtgt 5450

 gcgtgcctcg tacgtgtgtt atgggcactg gtctaggcca ggtatgacac 5500

 ccactctcct gtgagatttc actttagttt ttaaaaggtc cagttctaca 5550

 gagtgagacc tatctatctg agtactacat atgttttaag acttggttct 5600

 ttttttgagg gatccttgac cctgggaagt ctggagcacc ctgagaaggg 5650

 ggcaccatgt gtgcctttgc ccacgtgtcc tgaggggctg cttgtctggg 5700

 agggagggag agaacattca gcagcaggtg cttttttatg gccttttctt 5750

 aaaataacct aagggggaca catccatctt gcagagaagt ttacagaact 5800

 ccccttgaaa actgctgctg aggctcctgt taaattttct gtggcatctt 5850

 ttatgccttg gtaaaaactg cagtgtcttt ggacctgaga gtggctactc 5900

 cgtggttttg tgacctgtaa gcgtggggtt caggggtgtg tggccctgca 5950

 gggtcccacg cctccctgag cactgactgg aagtttcact ggctggtggc 6000

 tgtcccttct cccatcaggg tccccagcaa agttaactac acagaggacc 6050

 caggggaaac gagctgtgta gccactgact tgctcgcgcg gccgtggcct 6100

 ctgaggggca ctcgccggtt aagacagggt gggagtagtg ctttccagtt 6150

 cagactctaa cttctcccaa agtgtcctaa gaaaatactg gatcggctca 6200

 tagatttatg ctccttatga tgccctaact tggaaggttg ttctagggac 6250

 aggccgggca gtgtccccac acacacctta gagtcgaagg ccccagggcc 6300

 ccgctgtcac ttgcccaaaa gatcccttcc ggcaggtaag ggactaccaa 6350

 tgcttacgtc aaaacagcag aatcggcttt gcagtgcact ttggggagca 6400

 gatattaact tatttttgtg ttggacagta gtgaaatctt gtgattttta 6450

 atcgctttga taatacttcc aaattttatg atttttctga aggaaataat 6500

 gcaaacattt taaatatgtt tctccccctt tccaaaaact gttaaactaa 6550

 tgagcaagta acactaactt tgaatgtctc tacaataccc gttgataact 6600

 cagtggagcc aggctttggg gtagcggccc tgagcttgca gggtttctcg 6650

 ccactggggc tgaccacgcc cccagctgtg accgtgggtg tggctggctc 6700

 tcggccctgc ccagctttgt tctgaggacg tggtgacttc ctgaacatca 6750

 gcttcaatcc tccatcatta atgtgaagca aaacacaaaa accgccccaa 6800

 tccctcagga ttccttggca tccgaaacca gcatctgcac ctaaacccat 6850

 acccacccgt gtgcgcccac agggggatgt gtccgaatgg gcagcttaaa 6900

 atgtggtcac ctgtggggga aactcttcag gcacctgaag tgagaaccca 6950

 gctgtccgtc ctcaggccgg cctttcttcc ggcgacaccc gtccatggct 7000

 ggctgggtcc ccttcgcagt gtttgtctgt cttgacatct aaaccccggc 7050

 gtgtgcagtg cccatcttcc aggactacct tattttccag aattaaacct 7100

 gttttataat tcaagttaat gcaaatgact gtcagttgcc aaatatcttg 7150

 atcctgtgag tgtagttgat gactgtttgt tagtcagtag agtaaaatgc 7200

 tgtgtccacg gggtgtcaca gcctcaccat accctgttga ggtgtgaaat 7250

 gccccgtcag aaattaaata caaacttaaa tgtgcctatt ggtgtctaaa 7300

 cttcatacaa tgtaaggtca gattcctttt aggaatactg ggtgctgtca 7350

 ccaggtttga tagttagact taaaaacttg aaattcactt tttgggggga 7400

 gggatatact gaaatagaga gttgagactt gccagttggg ggaaaatagc 7450

 atttaaaatg gaaagctgtg tttggaaaat tgtgtatgag tatttttgta 7500

 ttaaaaacat tttaaaggct tttttcttaa 7530

<210> 1916
<211> 1365
<212> PRT
<213> Homo sapien

<400> 1916
 Met Glu Phe Ser Ile Lys Gln Ser Pro Leu Ser Val Gln Ser Val
   1               5                  10                  15

 Val Lys Cys Ile Lys Met Lys Gln Ala Pro Glu Ile Leu Gly Ser
                  20                  25                  30

 Ala Asn Gly Lys Thr Pro Ser Cys Glu Val Asn Arg Glu Cys Ser
                  35                  40                  45

 Val Phe Leu Ser Lys Ala Gln Leu Ser Ser Ser Leu Gln Glu Gly
                  50                  55                  60

 Val Met Gln Lys Phe Asn Gly His Asp Ala Leu Pro Phe Ile Pro
                  65                  70                  75

 Ala Asp Lys Leu Lys Asp Leu Thr Ser Arg Val Phe Asn Gly Glu
                  80                  85                  90

 Pro Gly Ala His Asp Ala Lys Leu Arg Phe Glu Ser Gln Glu Met
                  95                 100                 105

 Lys Gly Ile Gly Thr Pro Pro Asn Thr Thr Pro Ile Lys Asn Gly
                 110                 115                 120

 Ser Pro Glu Ile Lys Leu Lys Ile Thr Lys Thr Tyr Met Asn Gly
                 125                 130                 135

 Lys Pro Leu Phe Glu Ser Ser Ile Cys Gly Asp Ser Ala Ala Asp
                 140                 145                 150

 Val Ser Gln Ser Glu Glu Asn Gly Gln Lys Pro Glu Asn Lys Ala
                 155                 160                 165

 Arg Arg Asn Arg Lys Arg Ser Ile Lys Tyr Asp Ser Leu Leu Glu
                 170                 175                 180

 Gln Gly Leu Val Glu Ala Ala Leu Val Ser Lys Ile Ser Ser Pro
                 185                 190                 195

 Ser Asp Lys Lys Ile Pro Ala Lys Lys Glu Ser Cys Pro Asn Thr
                 200                 205                 210

 Gly Arg Asp Lys Asp His Leu Leu Lys Tyr Asn Val Gly Asp Leu
                 215                 220                 225

 Val Trp Ser Lys Val Ser Gly Tyr Pro Trp Trp Pro Cys Met Val
                 230                 235                 240

 Ser Ala Asp Pro Leu Leu His Ser Tyr Thr Lys Leu Lys Gly Gln
                 245                 250                 255

 Lys Lys Ser Ala Arg Gln Tyr His Val Gln Phe Phe Gly Asp Ala
                 260                 265                 270

 Pro Glu Arg Ala Trp Ile Phe Glu Lys Ser Leu Val Ala Phe Glu
                 275                 280                 285

 Gly Glu Gly Gln Phe Glu Lys Leu Cys Gln Glu Ser Ala Lys Gln
                 290                 295                 300

 Ala Pro Thr Lys Ala Glu Lys Ile Lys Leu Leu Lys Pro Ile Ser
                 305                 310                 315

 Gly Lys Leu Arg Ala Gln Trp Glu Met Gly Ile Val Gln Ala Glu
                 320                 325                 330

 Glu Ala Ala Ser Met Ser Val Glu Glu Arg Lys Ala Lys Phe Thr
                 335                 340                 345

 Phe Leu Tyr Val Gly Asp Gln Leu His Leu Asn Pro Gln Val Ala
                 350                 355                 360

 Lys Glu Ala Gly Ile Ala Ala Glu Ser Leu Gly Glu Met Ala Glu
                 365                 370                 375

 Ser Ser Gly Val Ser Glu Glu Ala Ala Glu Asn Pro Lys Ser Val
                 380                 385                 390

 Arg Glu Glu Cys Ile Pro Met Lys Arg Arg Arg Arg Ala Lys Leu
                 395                 400                 405

 Cys Ser Ser Ala Glu Thr Leu Glu Ser His Pro Asp Ile Gly Lys
                 410                 415                 420

 Ser Thr Pro Gln Lys Thr Ala Glu Ala Asp Pro Arg Arg Gly Val
                 425                 430                 435

 Gly Ser Pro Pro Gly Arg Lys Lys Thr Thr Val Ser Met Pro Arg
                 440                 445                 450

 Ser Arg Lys Gly Asp Ala Ala Ser Gln Phe Leu Val Phe Cys Gln
                 455                 460                 465

 Lys His Arg Asp Glu Val Val Ala Glu His Pro Asp Ala Ser Gly
                 470                 475                 480

 Glu Glu Ile Glu Glu Leu Leu Arg Ser Gln Trp Ser Leu Leu Ser
                 485                 490                 495

 Glu Lys Gln Arg Ala Arg Tyr Asn Thr Lys Phe Ala Leu Val Ala
                 500                 505                 510

 Pro Val Gln Ala Glu Glu Asp Ser Gly Asn Val Asn Gly Lys Lys
                 515                 520                 525

 Arg Asn His Thr Lys Arg Ile Gln Asp Pro Thr Glu Asp Ala Glu
                 530                 535                 540

 Ala Glu Asp Thr Pro Arg Lys Arg Leu Arg Thr Asp Lys His Ser
                 545                 550                 555

 Leu Arg Lys Arg Asp Thr Ile Thr Asp Lys Thr Ala Arg Thr Ser
                 560                 565                 570

 Ser Tyr Lys Ala Met Glu Ala Ala Ser Ser Leu Lys Ser Gln Ala
                 575                 580                 585

 Ala Thr Lys Asn Leu Ser Asp Ala Cys Lys Pro Leu Lys Lys Arg
                 590                 595                 600

 Asn Arg Ala Ser Thr Ala Ala Ser Ser Ala Leu Gly Phe Ser Lys
                 605                 610                 615

 Ser Ser Ser Pro Ser Ala Ser Leu Thr Glu Asn Glu Val Ser Asp
                 620                 625                 630

 Ser Pro Gly Asp Glu Pro Ser Glu Ser Pro Tyr Glu Ser Ala Asp
                 635                 640                 645

 Glu Thr Gln Thr Glu Val Ser Val Ser Ser Lys Lys Ser Glu Arg
                 650                 655                 660

 Gly Val Thr Ala Lys Lys Glu Tyr Val Cys Gln Leu Cys Glu Lys
                 665                 670                 675

 Pro Gly Ser Leu Leu Leu Cys Glu Gly Pro Cys Cys Gly Ala Phe
                 680                 685                 690

 His Leu Ala Cys Leu Gly Leu Ser Arg Arg Pro Glu Gly Arg Phe
                 695                 700                 705

 Thr Cys Ser Glu Cys Ala Ser Gly Ile His Ser Cys Phe Val Cys
                 710                 715                 720

 Lys Glu Ser Lys Thr Asp Val Lys Arg Cys Val Val Thr Gln Cys
                 725                 730                 735

 Gly Lys Phe Tyr His Glu Ala Cys Val Lys Lys Tyr Pro Leu Thr
                 740                 745                 750

 Val Phe Glu Ser Arg Gly Phe Arg Cys Pro Leu His Ser Cys Val
                 755                 760                 765

 Ser Cys His Ala Ser Asn Pro Ser Asn Pro Arg Pro Ser Lys Gly
                 770                 775                 780

 Lys Met Met Arg Cys Val Arg Cys Pro Val Ala Tyr His Ser Gly
                 785                 790                 795

 Asp Ala Cys Leu Ala Ala Gly Cys Ser Val Ile Ala Ser Asn Ser
                 800                 805                 810

 Ile Ile Cys Thr Ala His Phe Thr Ala Arg Lys Gly Lys Arg His
                 815                 820                 825

 His Ala His Val Asn Val Ser Trp Cys Phe Val Cys Ser Lys Gly
                 830                 835                 840

 Gly Ser Leu Leu Cys Cys Glu Ser Cys Pro Ala Ala Phe His Pro
                 845                 850                 855

 Asp Cys Leu Asn Ile Glu Met Pro Asp Gly Ser Trp Phe Cys Asn
                 860                 865                 870

 Asp Cys Arg Ala Gly Lys Lys Leu His Phe Gln Asp Ile Ile Trp
                 875                 880                 885

 Val Lys Leu Gly Asn Tyr Arg Trp Trp Pro Ala Glu Val Cys His
                 890                 895                 900

 Pro Lys Asn Val Pro Pro Asn Ile Gln Lys Met Lys His Glu Ile
                 905                 910                 915

 Gly Glu Phe Pro Val Phe Phe Phe Gly Ser Lys Asp Tyr Tyr Trp
                 920                 925                 930

 Thr His Gln Ala Arg Val Phe Pro Tyr Met Glu Gly Asp Arg Gly
                 935                 940                 945

 Ser Arg Tyr Gln Gly Val Arg Gly Ile Gly Arg Val Phe Lys Asn
                 950                 955                 960

 Ala Leu Gln Glu Ala Glu Ala Arg Phe Arg Glu Ile Lys Leu Gln
                 965                 970                 975

 Arg Glu Ala Arg Glu Thr Gln Glu Ser Glu Arg Lys Pro Pro Pro
                 980                 985                 990

 Tyr Lys His Ile Lys Val Asn Lys Pro Tyr Gly Lys Val Gln Ile
                 995                1000                1005

 Tyr Thr Ala Asp Ile Ser Glu Ile Pro Lys Cys Asn Cys Lys Pro
                1010                1015                1020

 Thr Asp Glu Asn Pro Cys Gly Phe Asp Ser Glu Cys Leu Asn Arg
                1025                1030                1035

 Met Leu Met Phe Glu Cys His Pro Gln Val Cys Pro Ala Gly Glu
                1040                1045                1050

 Phe Cys Gln Asn Gln Cys Phe Thr Lys Arg Gln Tyr Pro Glu Thr
                1055                1060                1065

 Lys Ile Ile Lys Thr Asp Gly Lys Gly Trp Gly Leu Val Ala Lys
                1070                1075                1080

 Arg Asp Ile Arg Lys Gly Glu Phe Val Asn Glu Tyr Val Gly Glu
                1085                1090                1095

 Leu Ile Asp Glu Glu Glu Cys Met Ala Arg Ile Lys His Ala His
                1100                1105                1110

 Glu Asn Asp Ile Thr His Phe Tyr Met Leu Thr Ile Asp Lys Asp
                1115                1120                1125

 Arg Ile Ile Asp Ala Gly Pro Lys Gly Asn Tyr Ser Arg Phe Met
                1130                1135                1140

 Asn His Ser Cys Gln Pro Asn Cys Glu Thr Leu Lys Trp Thr Val
                1145                1150                1155

 Asn Gly Asp Thr Arg Val Gly Leu Phe Ala Val Cys Asp Ile Pro
                1160                1165                1170

 Ala Gly Thr Glu Leu Thr Phe Asn Tyr Asn Leu Asp Cys Leu Gly
                1175                1180                1185

 Asn Glu Lys Thr Val Cys Arg Cys Gly Ala Ser Asn Cys Ser Gly
                1190                1195                1200

 Phe Leu Gly Asp Arg Pro Lys Thr Ser Thr Thr Leu Ser Ser Glu
                1205                1210                1215

 Glu Lys Gly Lys Lys Thr Lys Lys Lys Thr Arg Arg Arg Arg Ala
                1220                1225                1230

 Lys Gly Glu Gly Lys Arg Gln Ser Glu Asp Glu Cys Phe Arg Cys
                1235                1240                1245

 Gly Asp Gly Gly Gln Leu Val Leu Cys Asp Arg Lys Phe Cys Thr
                1250                1255                1260

 Lys Ala Tyr His Leu Ser Cys Leu Gly Leu Gly Lys Arg Pro Phe
                1265                1270                1275

 Gly Lys Trp Glu Cys Pro Trp His His Cys Asp Val Cys Gly Lys
                1280                1285                1290

 Pro Ser Thr Ser Phe Cys His Leu Cys Pro Asn Ser Phe Cys Lys
                1295                1300                1305

 Glu His Gln Asp Gly Thr Ala Phe Ser Cys Thr Pro Asp Gly Arg
                1310                1315                1320

 Ser Tyr Cys Cys Glu His Asp Leu Gly Ala Ala Ser Val Arg Ser
                1325                1330                1335

 Thr Lys Thr Glu Lys Pro Pro Pro Glu Pro Gly Lys Pro Lys Gly
                1340                1345                1350

 Lys Arg Arg Arg Arg Arg Gly Trp Arg Arg Val Thr Glu Gly Lys
                1355                1360                1365

<210> 1917
<211> 3619
<212> DNA
<213> Homo sapien

<400> 1917
 gagtagcatt gtggttatat gtaagacttt atgtttagag atttgtgcta 50

 aacttcttat ggatgaaatg atatgtctgg gatttgcttc agaataatct 100

 ggcaggggga cgtggaacca ggtatggata gagccacgct ggccccaggt 150

 tgatgttttt gggggccaag tagcgaggac atggggttca ttgtacagtt 200

 tgtctgcttt tgtttatgtt cagatttttc catgatagaa agttaagcca 250

 gaaggacaaa ggaattcaga agattcatct ttagaacttc acttatttga 300

 ggggtaattt ttaagcagta aaaagatcaa gggtttatga tttgaaactt 350

 tacaaaccaa aattatttta cagcaacgaa aaatctgtct gatgcatgta 400

 aaccactgaa gaagcgaaat cgggcttcca cggcagcatc ttcagctctt 450

 gggtttagca aaagttcatc tccttctgca tccttaactg agaatgaggt 500

 ctcggacagc ccgggagacg agccctcgga gtccccatac gaaagtgcag 550

 acgaaacaca aactgaagta tctgtctcat ccaaaaagtc tgagcgagga 600

 gtgactgcca aaaaggagta tgtgtgccag ctgtgtgaga agccgggcag 650

 cctcctgctc tgtgaaggac cctgctgcgg agctttccac ctcgcctgcc 700

 ttgggctttc ccggaggcca gaagggaggt tcacctgcag cgagtgtgcc 750

 tcagggattc actcatgttt cgtgtgtaaa gagagcaaga cagatgttaa 800

 gcgctgtgtg gtaactcagt gtggaaaatt ttaccatgag gcttgtgtga 850

 aaaaataccc tctgactgta tttgagagcc gaggtttccg ctgccccctc 900

 cacagctgtg tgagctgcca tgcttccaac ccttcaaacc caaggccgtc 950

 aaaaggtaaa atgatgcggt gtgtccgctg ccccgttgcc tatcacagcg 1000

 gggatgcttg tctggcagca ggatgctcag tgatcgcctc caacagcatc 1050

 atctgcactg cccacttcac tgctcggaag gggaagcgac accacgccca 1100

 cgtcaacgtg agctggtgct tcgtgtgctc caaagggggg agccttctgt 1150

 gctgtgagtc ctgcccagcg gccttccacc ctgactgcct gaacatcgag 1200

 atgcctgacg gcagctggtt ctgcaatgac tgcagggctg ggaagaagtt 1250

 gcacttccag gatatcattt gggtgaaact tgggaactac agatggtggc 1300

 cggcagaagt ttgccatccc aaaaatgttc ccccaaatat tcagaaaatg 1350

 aagcacgaga ttggagaatt ccctgtgttt ttctttgggt ctaaagatta 1400

 ttactggacg catcaggcgc gagtgttccc gtacatggag ggggaccggg 1450

 gcagccgcta ccagggggtc agagggatcg gaagagtctt caaaaacgca 1500

 ctgcaagaag ctgaagctcg ttttcgtgaa attaagcttc agagggaagc 1550

 ccgagaaaca caggagagcg agcgcaagcc cccaccatac aagcacatca 1600

 aggtgaataa gccttacggg aaagtccaga tctacacagc ggatatttca 1650

 gaaatcccta agtgcaactg caagcccaca gatgagaatc cttgtggctt 1700

 tgattcggag tgtctgaaca ggatgctgat gtttgagtgc cacccgcagg 1750

 tgtgtcccgc gggcgagttc tgccagaacc agtgcttcac caagcgccag 1800

 tacccagaga ccaagatcat caagacagat ggcaaagggt ggggcctggt 1850

 cgccaagagg gacatcagaa agggagaatt tgttaacgag tacgttgggg 1900

 agctgatcga cgaggaggag tgcatggcga gaatcaagca cgcacacgag 1950

 aacgacatca cccacttcta catgctcact atagacaagg accgtataat 2000

 agacgctggc cccaaaggaa actactctcg atttatgaat cacagctgcc 2050

 agcccaactg tgagaccctc aagtggacag tgaatgggga cactcgtgtg 2100

 ggcctgtttg ccgtctgtga cattcctgca gggacggagc tgacttttaa 2150

 ctacaacctc gattgcctgg gcaatgaaaa aacggtctgc cggtgtggag 2200

 cctccaattg cagtggattc ctcggggata gaccaaagac ctcgacgacc 2250

 ctttcatcag aggaaaaggg caaaaagacc aagaagaaaa cgaggcggcg 2300

 cagagcaaaa ggggaaggga agaggcagtc agaggacgag tgcttccgct 2350

 gcggtgatgg cgggcagctg gtgctgtgtg accgcaagtt ctgcaccaag 2400

 gcctaccacc tgtcctgcct gggccttggc aagcggccct tcgggaagtg 2450

 ggaatgtcct tggcatcatt gtgacgtgtg tggcaaacct tcgacttcat 2500

 tttgccacct ctgccccaat tcgttctgta aggagcacca ggacgggaca 2550

 gccttcagct gcaccccgga cgggcggtcc tactgctgtg agcatgactt 2600

 aggggcggca tcggtcagaa gcaccaagac tgagaagccc cccccagagc 2650

 cagggaagcc gaaggggaag aggcggcggc ggaggggctg gcggagagtc 2700

 acagagggca aatagcgcca ggcggccgct tggccggatc caggggcggt 2750

 gcagggcggc cggccctgcc tgcgggagag ggcgagcatg aactggcccg 2800

 gaggacccag ctcgagccgc caggacacag acgtacaggc ctcctcggga 2850

 gggagcgcct ccccaccact gagccatcct cagcagcgtc cgctgcgtct 2900

 gcactgatga ccgtctgagc ccagctcagc gttcctggac aaacagcctc 2950

 actcctcagc gttaccgcca cacttgaatt tctccgaatg tcaaggttcc 3000

 ctcccactct atttttttag gttaaagtta attggcatat ggaatgtttt 3050

 aatctcctct gaaatgtgta gcgtaggctt ttcccaaggg tcgctagaaa 3100

 ctcgtcttcg cgttgccccc tttctggctc tcagcgccgt cgccactcgg 3150

 gagaggctgg gtgaggcccg tgtgaggact gaccctggat tcctcgaaac 3200

 tgccattgtg atcattactc tgctctttgg aaatggctgt atcatttttt 3250

 tgtactaatg tgaattgttc ctcagaaacg cttcttttcc atcctagtga 3300

 gaagctggcc ctgcaggtgg tggcagcaat ggtgttgtaa gatttcctcc 3350

 cgtagttttt tctcctcatg gatttgaatg aaatgccaat aacacgtcca 3400

 ctttcaacgt gtagtttacg cggagcactt tcgaggcctg gccgggttgg 3450

 gcctacttct cacctgggcc tatcttctga actcgctagg ttcttatcaa 3500

 catttggggg ataactttgt atattttttt catttggctt ttctttacca 3550

 gtttctgatt tttattctca atatattttt gctaaaccta tttcacaaat 3600

 caaaaaaaaa aaaaaaaaa 3619

<210> 1918
<211> 584
<212> PRT
<213> Homo sapien

<400> 1918
 Met Met Arg Cys Val Arg Cys Pro Val Ala Tyr His Ser Gly Asp
   1               5                  10                  15

 Ala Cys Leu Ala Ala Gly Cys Ser Val Ile Ala Ser Asn Ser Ile
                  20                  25                  30

 Ile Cys Thr Ala His Phe Thr Ala Arg Lys Gly Lys Arg His His
                  35                  40                  45

 Ala His Val Asn Val Ser Trp Cys Phe Val Cys Ser Lys Gly Gly
                  50                  55                  60

 Ser Leu Leu Cys Cys Glu Ser Cys Pro Ala Ala Phe His Pro Asp
                  65                  70                  75

 Cys Leu Asn Ile Glu Met Pro Asp Gly Ser Trp Phe Cys Asn Asp
                  80                  85                  90

 Cys Arg Ala Gly Lys Lys Leu His Phe Gln Asp Ile Ile Trp Val
                  95                 100                 105

 Lys Leu Gly Asn Tyr Arg Trp Trp Pro Ala Glu Val Cys His Pro
                 110                 115                 120

 Lys Asn Val Pro Pro Asn Ile Gln Lys Met Lys His Glu Ile Gly
                 125                 130                 135

 Glu Phe Pro Val Phe Phe Phe Gly Ser Lys Asp Tyr Tyr Trp Thr
                 140                 145                 150

 His Gln Ala Arg Val Phe Pro Tyr Met Glu Gly Asp Arg Gly Ser
                 155                 160                 165

 Arg Tyr Gln Gly Val Arg Gly Ile Gly Arg Val Phe Lys Asn Ala
                 170                 175                 180

 Leu Gln Glu Ala Glu Ala Arg Phe Arg Glu Ile Lys Leu Gln Arg
                 185                 190                 195

 Glu Ala Arg Glu Thr Gln Glu Ser Glu Arg Lys Pro Pro Pro Tyr
                 200                 205                 210

 Lys His Ile Lys Val Asn Lys Pro Tyr Gly Lys Val Gln Ile Tyr
                 215                 220                 225

 Thr Ala Asp Ile Ser Glu Ile Pro Lys Cys Asn Cys Lys Pro Thr
                 230                 235                 240

 Asp Glu Asn Pro Cys Gly Phe Asp Ser Glu Cys Leu Asn Arg Met
                 245                 250                 255

 Leu Met Phe Glu Cys His Pro Gln Val Cys Pro Ala Gly Glu Phe
                 260                 265                 270

 Cys Gln Asn Gln Cys Phe Thr Lys Arg Gln Tyr Pro Glu Thr Lys
                 275                 280                 285

 Ile Ile Lys Thr Asp Gly Lys Gly Trp Gly Leu Val Ala Lys Arg
                 290                 295                 300

 Asp Ile Arg Lys Gly Glu Phe Val Asn Glu Tyr Val Gly Glu Leu
                 305                 310                 315

 Ile Asp Glu Glu Glu Cys Met Ala Arg Ile Lys His Ala His Glu
                 320                 325                 330

 Asn Asp Ile Thr His Phe Tyr Met Leu Thr Ile Asp Lys Asp Arg
                 335                 340                 345

 Ile Ile Asp Ala Gly Pro Lys Gly Asn Tyr Ser Arg Phe Met Asn
                 350                 355                 360

 His Ser Cys Gln Pro Asn Cys Glu Thr Leu Lys Trp Thr Val Asn
                 365                 370                 375

 Gly Asp Thr Arg Val Gly Leu Phe Ala Val Cys Asp Ile Pro Ala
                 380                 385                 390

 Gly Thr Glu Leu Thr Phe Asn Tyr Asn Leu Asp Cys Leu Gly Asn
                 395                 400                 405

 Glu Lys Thr Val Cys Arg Cys Gly Ala Ser Asn Cys Ser Gly Phe
                 410                 415                 420

 Leu Gly Asp Arg Pro Lys Thr Ser Thr Thr Leu Ser Ser Glu Glu
                 425                 430                 435

 Lys Gly Lys Lys Thr Lys Lys Lys Thr Arg Arg Arg Arg Ala Lys
                 440                 445                 450

 Gly Glu Gly Lys Arg Gln Ser Glu Asp Glu Cys Phe Arg Cys Gly
                 455                 460                 465

 Asp Gly Gly Gln Leu Val Leu Cys Asp Arg Lys Phe Cys Thr Lys
                 470                 475                 480

 Ala Tyr His Leu Ser Cys Leu Gly Leu Gly Lys Arg Pro Phe Gly
                 485                 490                 495

 Lys Trp Glu Cys Pro Trp His His Cys Asp Val Cys Gly Lys Pro
                 500                 505                 510

 Ser Thr Ser Phe Cys His Leu Cys Pro Asn Ser Phe Cys Lys Glu
                 515                 520                 525

 His Gln Asp Gly Thr Ala Phe Ser Cys Thr Pro Asp Gly Arg Ser
                 530                 535                 540

 Tyr Cys Cys Glu His Asp Leu Gly Ala Ala Ser Val Arg Ser Thr
                 545                 550                 555

 Lys Thr Glu Lys Pro Pro Pro Glu Pro Gly Lys Pro Lys Gly Lys
                 560                 565                 570

 Arg Arg Arg Arg Arg Gly Trp Arg Arg Val Thr Glu Gly Lys
                 575                 580

<210> 1919
<211> 6754
<212> DNA
<213> Homo sapien

<400> 1919
 gtcgacgtgg cggccggcgg cggctgcggg ctgagcggcg agtttccgat 50

 ttaaagctga gctgcgagga aaatggcggc gggaggatca aaatacttgc 100

 tggatggtgg actcagagac caataaaaat aaactgcttg aacatccttt 150

 gactggttag ccagttgctg atgtatattc aagatgagtg gattaggaga 200

 aaacttggat ccactggcca gtgattcacg aaaacgcaaa ttgccatgtg 250

 atactccagg acaaggtctt acctgcagtg gtgaaaaacg gagacgggag 300

 caggaaagta aatatattga agaattggct gagctgatat ctgccaatct 350

 tagtgatatt gacaatttca atgtcaaacc agataaatgt gcgattttaa 400

 aggaaacagt aagacagata cgtcaaataa aagagcaagg aaaaactatt 450

 tccaatgatg atgatgttca aaaagccgat gtatcttcta cagggcaggg 500

 agttattgat aaagactcct taggaccgct tttacttcag gcattggatg 550

 gtttcctatt tgtggtgaat cgagacggaa acattgtatt tgtatcagaa 600

 aatgtcacac aatacctgca atataagcaa gaggacctgg ttaacacaag 650

 tgtttacaat atcttacatg aagaagacag aaaggatttt cttaagaatt 700

 taccaaaatc tacagttaat ggagtttcct ggacaaatga gacccaaaga 750

 caaaaaagcc atacatttaa ttgccgtatg ttgatgaaaa caccacatga 800

 tattctggaa gacataaacg ccagtcctga aatgcgccag agatatgaaa 850

 caatgcagtg ctttgccctg tctcagccac gagctatgat ggaggaaggg 900

 gaagatttgc aatcttgtat gatctgtgtg gcacgccgca ttactacagg 950

 agaaagaaca tttccatcaa accctgagag ctttattacc agacatgatc 1000

 tttcaggaaa ggttgtcaat atagatacaa attcactgag atcctccatg 1050

 aggcctggct ttgaagatat aatccgaagg tgtattcaga gattttttag 1100

 tctaaatgat gggcagtcat ggtcccagaa acgtcactat caagaagtta 1150

 ccagtgatgg gatattttcc ccaacagctt atcttaatgg ccatgcagaa 1200

 accccagtat atcgattctc gttggctgat ggaactatag tgactgcaca 1250

 gacaaaaagc aaactcttcc gaaatcctgt aacaaatgat cgacatggct 1300

 ttgtctcaac ccacttcctt cagagagaac agaatggata tagaccaaac 1350

 ccaaatcctg ttggacaagg gattagacca cctatggctg gatgcaacag 1400

 ttcggtaggc ggcatgagta tgtcgccaaa ccaaggctta cagatgccga 1450

 gcagcagggc ctatggcttg gcagacccta gcaccacagg gcagatgagt 1500

 ggagctaggt atgggggttc cagtaacata gcttcattga cccctgggcc 1550

 aggcatgcaa tcaccatctt cctaccagaa caacaactat aggctcaaca 1600

 tgagtagccc cccacatggg agtcctggtc ttgccccaaa ccagcagaat 1650

 atcatgattt ctcctcgtaa tcgtgggagt ccaaagatag cctcacatca 1700

 gttttctcct gttgcaggtg tgcactctcc catggcatct tctggcaata 1750

 ctgggaacca cagcttttcc agcagctctc tcagtgccct gcaagccatc 1800

 agtgaaggtg tggggacttc ccttttatct actctgtcat caccaggccc 1850

 caaattggat aactctccca atatgaatat tacccaacca agtaaagtaa 1900

 gcaatcagga ttccaagagt cctctgggct tttattgcga ccaaaatcca 1950

 gtggagagtt caatgtgtca gtcaaatagc agagatcacc tcagtgacaa 2000

 agaaagtaag gagagcagtg ttgagggggc agagaatcaa aggggtcctt 2050

 tggaaagcaa aggtcataaa aaattactgc agttacttac ctgttcttct 2100

 gatgaccggg gtcattcctc cttgaccaac tcccccctag attcaagttg 2150

 taaagaatct tctgttagtg tcaccagccc ctctggagtc tcctcctcta 2200

 catctggagg agtatcctct acatccaata tgcatgggtc actgttacaa 2250

 gagaagcacc ggattttgca caagttgctg cagaatggga attcaccagc 2300

 tgaggtagcc aagattactg cagaagccac tgggaaagac accagcagta 2350

 taacttcttg tggggacgga aatgttgtca agcaggagca gctaagtcct 2400

 aagaagaagg agaataatgc acttcttaga tacctgctgg acagggatga 2450

 tcctagtgat gcactctcta aagaactaca gccccaagtg gaaggagtgg 2500

 ataataaaat gagtcagtgc accagctcca ccattcctag ctcaagtcaa 2550

 gagaaagacc ctaaaattaa gacagagaca agtgaagagg gatctggaga 2600

 cttggataat ctagatgcta ttcttggtga tctgactagt tctgactttt 2650

 acaataattc catatcctca aatggtagtc atctggggac taagcaacag 2700

 gtgtttcaag gaactaattc tctgggtttg aaaagttcac agtctgtgca 2750

 gtctattcgt cctccatata accgagcagt gtctctggat agccctgttt 2800

 ctgttggctc aagtcctcca gtaaaaaata tcagtgcttt ccccatgtta 2850

 ccaaagcaac ccatgttggg tgggaatcca agaatgatgg atagtcagga 2900

 aaattatggc tcaagtatgg gagactgggg cttaccaaac tcaaaggccg 2950

 gcagaatgga acctatgaat tcaaactcca tgggaagacc aggaggagat 3000

 tataatactt ctttacccag acctgcactg ggtggctcta ttcccacatt 3050

 gcctcttcgg tctaatagca taccaggtgc gagaccagta ttgcaacagc 3100

 agcagcagat gcttcaaatg aggcctggtg aaatccccat gggaatgggg 3150

 gctaatccct atggccaagc agcagcatct aaccaactgg gttcctggcc 3200

 cgatggcatg ttgtccatgg aacaagtttc tcatggcact caaaataggc 3250

 ctcttcttag gaattccctg gatgatcttg ttgggccacc ttccaacctg 3300

 gaaggccaga gtgacgaaag agcattattg gaccagctgc acactcttct 3350

 cagcaacaca gatgccacag gcctggaaga aattgacaga gctttgggca 3400

 ttcctgaact tgtcaatcag ggacaggcat tagagcccaa acaggatgct 3450

 ttccaaggcc aagaagcagc agtaatgatg gatcagaagg caggattata 3500

 tggacagaca tacccagcac aggggcctcc aatgcaagga ggctttcatc 3550

 ttcagggaca atcaccatct tttaactcta tgatgaatca gatgaaccag 3600

 caaggcaatt ttcctctcca aggaatgcac ccacgagcca acatcatgag 3650

 accccggaca aacaccccca agcaacttag aatgcagctt cagcagaggc 3700

 tgcagggcca gcagtttttg aatcagagcc gacaggcact tgaattgaaa 3750

 atggaaaacc ctactgctgg tggtgctgcg gtgatgaggc ctatgatgca 3800

 gccccagcag ggttttctta atgctcaaat ggtcgcccaa cgcagcagag 3850

 agctgctaag tcatcacttc cgacaacaga gggtggctat gatgatgcag 3900

 cagcagcaac agcagcagca gcagcagcag cagcagcaac agcaacagca 3950

 acagcaacag cagcaacagc agcaaaccca ggccttcagc ccacctccta 4000

 atgtgactgc ttcccccagc atggatgggc ttttggcagg acccacaatg 4050

 ccacaagctc ctccgcaaca gtttccatat caaccaaatt atggaatggg 4100

 acaacaacca gatccagcct ttggtcgagt gtctagtcct cccaatgcaa 4150

 tgatgtcgtc aagaatgggt ccctcccaga atcccatgat gcaacacccg 4200

 caggctgcat ccatctatca gtcctcagaa atgaagggct ggccatcagg 4250

 aaatttggcc aggaacagct ccttttccca gcagcagttt gcccaccagg 4300

 ggaatcctgc agtgtatagt atggtgcaca tgaatggcag cagtggtcac 4350

 atgggacaga tgaacatgaa ccccatgccc atgtctggca tgcctatggg 4400

 tcctgatcag aaatactgct gacatctctg caccaggacc tcttaaggaa 4450

 accactgtac aaatgacact gcactaggat tattgggaag gaatcattgt 4500

 tccaggcatc catcttggaa gaaaggacca gctttgagct ccatcaaggg 4550

 tattttaagt gatgtcattt gagcaggact ggattttaag ccgaagggca 4600

 atatctacgt gtttttcccc cctccttctg ctgtgtatca tggtgttcaa 4650

 aacagaaatg ttttttggca ttccacctcc tagggatata attctggaga 4700

 catggagtgt tactgatcat aaaacttttg tgtcactttt ttctgccttg 4750

 ctagccaaaa tctcttaaat acacgtaggt gggccagaga acattggaag 4800

 aatcaagaga gattagaata tctggtttct ctagttgcag tattggacaa 4850

 agagcatagt cccagccttc aggtgtagta gttctgtgtt gaccctttgt 4900

 ccagtggaat tggtgattct gaattgtcct ttactaatgg tgttgagttg 4950

 ctctgtccct attatttgcc ctaggctttc tcctaatgaa ggttttcatt 5000

 tgccattcat gtcctgtaat acttcacctc caggaactgt catggatgtc 5050

 caaatggctt tgcagaaagg aaatgagatg acagtattta atcgcagcag 5100

 tagcaaactt ttcacatgct aatgtgcagc tgagtgcact ttatttaaaa 5150

 agaatggata aatgcaatat tcttgaggtc ttgagggaat agtgaaacac 5200

 attcctggtt tttgcctaca cttacgtgtt agacaagaac tatgattttt 5250

 ttttttaaag tactggtgtc accctttgcc tatatggtag agcaataatg 5300

 ctttttaaaa ataaacttct gaaaacccaa ggccaggtac tgcattctga 5350

 atcagaatct cgcagtgttt ctgtgaatag atttttttgt aaatatgacc 5400

 tttaagatat tgtattatgt aaaatatgta tatacctttt tttgtaggtc 5450

 acaacaactc atttttacag agtttgtgaa gctaaatatt taacattgtt 5500

 gatttcagta agctgtgtgg tgaggctacc agtggaagag acatcccttg 5550

 acttttgtgg cctgggggag gggtagtgca ccacagcttt tccttcccca 5600

 ccccccagcc ttagatgcct cgctcttttc aatctcttaa tctaaatgct 5650

 ttttaaagag attatttgtt tagatgtagg cattttaatt ttttaaaaat 5700

 tcctctacca gaactaagca ctttgttaat ttggggggaa agaatagata 5750

 tggggaaata aacttaaaaa aaaatcagga atttaaaaaa aacgagcaat 5800

 ttgaagagaa tcttttggat tttaagcagt ccgaaataat agcaattcat 5850

 gggctgtgtg tgtgtgtgta tgtgtgtgtg tgtgtgtgta tgtttaatta 5900

 tgttaccttt tcatcccctt taggagcgtt ttcagatttt ggttcgtaag 5950

 acctgaatcc catattgaga tctcgagtag aatccttggt gtggtttctg 6000

 gtgtctgctc agctgtcccc tcattctact aatgtgatgc tttcattatg 6050

 tccctgtgga ttagaatagt gtcagttatt tcttaagtaa ctcagtaccc 6100

 agaacagcca gttttactgt gattcagagc cacagtctaa ctgagcacct 6150

 tttaaacccc tccctcttct gccccctacc acttttctgc tgttgcctct 6200

 ctttgacacc tgttttagtc agttgggagg aagggaaaaa tcaagtttaa 6250

 ttccctttat ctgggttaat tcatttggtt caaatagttg acggaattgg 6300

 gtttctgaat gtctgtgaat ttcagaggtc tctgctagcc ttggtatcat 6350

 tttctagcaa taactgagag ccagttaatt ttaagaattt cacacattta 6400

 gccaatcttt ctagatgtct ctgaaggtaa gatcatttaa tatctttgat 6450

 atgcttacga gtaagtgaat cctgattatt tccagaccca ccaccagagt 6500

 ggatcttatt ttcaaagcag tatagacaat tatgagtttg ccctctttcc 6550

 cctaccaagt tcaaaatata tctaagaaag attgtaaatc cgaaaacttc 6600

 cattgtagtg gcctgtgctt ttcagatagt atactctcct gtttggagac 6650

 agaggaagaa ccaggtcagt ctgtctcttt ttcagctcaa ttgtatctga 6700

 cccttcttta agttatgtgt gtggggagaa atagaatggt gctcttatgt 6750

 cgac 6754

<210> 1920
<211> 1412
<212> PRT
<213> Homo sapien

<400> 1920
 Met Ser Gly Leu Gly Glu Asn Leu Asp Pro Leu Ala Ser Asp Ser
   1               5                  10                  15

 Arg Lys Arg Lys Leu Pro Cys Asp Thr Pro Gly Gln Gly Leu Thr
                  20                  25                  30

 Cys Ser Gly Glu Lys Arg Arg Arg Glu Gln Glu Ser Lys Tyr Ile
                  35                  40                  45

 Glu Glu Leu Ala Glu Leu Ile Ser Ala Asn Leu Ser Asp Ile Asp
                  50                  55                  60

 Asn Phe Asn Val Lys Pro Asp Lys Cys Ala Ile Leu Lys Glu Thr
                  65                  70                  75

 Val Arg Gln Ile Arg Gln Ile Lys Glu Gln Gly Lys Thr Ile Ser
                  80                  85                  90

 Asn Asp Asp Asp Val Gln Lys Ala Asp Val Ser Ser Thr Gly Gln
                  95                 100                 105

 Gly Val Ile Asp Lys Asp Ser Leu Gly Pro Leu Leu Leu Gln Ala
                 110                 115                 120

 Leu Asp Gly Phe Leu Phe Val Val Asn Arg Asp Gly Asn Ile Val
                 125                 130                 135

 Phe Val Ser Glu Asn Val Thr Gln Tyr Leu Gln Tyr Lys Gln Glu
                 140                 145                 150

 Asp Leu Val Asn Thr Ser Val Tyr Asn Ile Leu His Glu Glu Asp
                 155                 160                 165

 Arg Lys Asp Phe Leu Lys Asn Leu Pro Lys Ser Thr Val Asn Gly
                 170                 175                 180

 Val Ser Trp Thr Asn Glu Thr Gln Arg Gln Lys Ser His Thr Phe
                 185                 190                 195

 Asn Cys Arg Met Leu Met Lys Thr Pro His Asp Ile Leu Glu Asp
                 200                 205                 210

 Ile Asn Ala Ser Pro Glu Met Arg Gln Arg Tyr Glu Thr Met Gln
                 215                 220                 225

 Cys Phe Ala Leu Ser Gln Pro Arg Ala Met Met Glu Glu Gly Glu
                 230                 235                 240

 Asp Leu Gln Ser Cys Met Ile Cys Val Ala Arg Arg Ile Thr Thr
                 245                 250                 255

 Gly Glu Arg Thr Phe Pro Ser Asn Pro Glu Ser Phe Ile Thr Arg
                 260                 265                 270

 His Asp Leu Ser Gly Lys Val Val Asn Ile Asp Thr Asn Ser Leu
                 275                 280                 285

 Arg Ser Ser Met Arg Pro Gly Phe Glu Asp Ile Ile Arg Arg Cys
                 290                 295                 300

 Ile Gln Arg Phe Phe Ser Leu Asn Asp Gly Gln Ser Trp Ser Gln
                 305                 310                 315

 Lys Arg His Tyr Gln Glu Val Thr Ser Asp Gly Ile Phe Ser Pro
                 320                 325                 330

 Thr Ala Tyr Leu Asn Gly His Ala Glu Thr Pro Val Tyr Arg Phe
                 335                 340                 345

 Ser Leu Ala Asp Gly Thr Ile Val Thr Ala Gln Thr Lys Ser Lys
                 350                 355                 360

 Leu Phe Arg Asn Pro Val Thr Asn Asp Arg His Gly Phe Val Ser
                 365                 370                 375

 Thr His Phe Leu Gln Arg Glu Gln Asn Gly Tyr Arg Pro Asn Pro
                 380                 385                 390

 Asn Pro Val Gly Gln Gly Ile Arg Pro Pro Met Ala Gly Cys Asn
                 395                 400                 405

 Ser Ser Val Gly Gly Met Ser Met Ser Pro Asn Gln Gly Leu Gln
                 410                 415                 420

 Met Pro Ser Ser Arg Ala Tyr Gly Leu Ala Asp Pro Ser Thr Thr
                 425                 430                 435

 Gly Gln Met Ser Gly Ala Arg Tyr Gly Gly Ser Ser Asn Ile Ala
                 440                 445                 450

 Ser Leu Thr Pro Gly Pro Gly Met Gln Ser Pro Ser Ser Tyr Gln
                 455                 460                 465

 Asn Asn Asn Tyr Arg Leu Asn Met Ser Ser Pro Pro His Gly Ser
                 470                 475                 480

 Pro Gly Leu Ala Pro Asn Gln Gln Asn Ile Met Ile Ser Pro Arg
                 485                 490                 495

 Asn Arg Gly Ser Pro Lys Ile Ala Ser His Gln Phe Ser Pro Val
                 500                 505                 510

 Ala Gly Val His Ser Pro Met Ala Ser Ser Gly Asn Thr Gly Asn
                 515                 520                 525

 His Ser Phe Ser Ser Ser Ser Leu Ser Ala Leu Gln Ala Ile Ser
                 530                 535                 540

 Glu Gly Val Gly Thr Ser Leu Leu Ser Thr Leu Ser Ser Pro Gly
                 545                 550                 555

 Pro Lys Leu Asp Asn Ser Pro Asn Met Asn Ile Thr Gln Pro Ser
                 560                 565                 570

 Lys Val Ser Asn Gln Asp Ser Lys Ser Pro Leu Gly Phe Tyr Cys
                 575                 580                 585

 Asp Gln Asn Pro Val Glu Ser Ser Met Cys Gln Ser Asn Ser Arg
                 590                 595                 600

 Asp His Leu Ser Asp Lys Glu Ser Lys Glu Ser Ser Val Glu Gly
                 605                 610                 615

 Ala Glu Asn Gln Arg Gly Pro Leu Glu Ser Lys Gly His Lys Lys
                 620                 625                 630

 Leu Leu Gln Leu Leu Thr Cys Ser Ser Asp Asp Arg Gly His Ser
                 635                 640                 645

 Ser Leu Thr Asn Ser Pro Leu Asp Ser Ser Cys Lys Glu Ser Ser
                 650                 655                 660

 Val Ser Val Thr Ser Pro Ser Gly Val Ser Ser Ser Thr Ser Gly
                 665                 670                 675

 Gly Val Ser Ser Thr Ser Asn Met His Gly Ser Leu Leu Gln Glu
                 680                 685                 690

 Lys His Arg Ile Leu His Lys Leu Leu Gln Asn Gly Asn Ser Pro
                 695                 700                 705

 Ala Glu Val Ala Lys Ile Thr Ala Glu Ala Thr Gly Lys Asp Thr
                 710                 715                 720

 Ser Ser Ile Thr Ser Cys Gly Asp Gly Asn Val Val Lys Gln Glu
                 725                 730                 735

 Gln Leu Ser Pro Lys Lys Lys Glu Asn Asn Ala Leu Leu Arg Tyr
                 740                 745                 750

 Leu Leu Asp Arg Asp Asp Pro Ser Asp Ala Leu Ser Lys Glu Leu
                 755                 760                 765

 Gln Pro Gln Val Glu Gly Val Asp Asn Lys Met Ser Gln Cys Thr
                 770                 775                 780

 Ser Ser Thr Ile Pro Ser Ser Ser Gln Glu Lys Asp Pro Lys Ile
                 785                 790                 795

 Lys Thr Glu Thr Ser Glu Glu Gly Ser Gly Asp Leu Asp Asn Leu
                 800                 805                 810

 Asp Ala Ile Leu Gly Asp Leu Thr Ser Ser Asp Phe Tyr Asn Asn
                 815                 820                 825

 Ser Ile Ser Ser Asn Gly Ser His Leu Gly Thr Lys Gln Gln Val
                 830                 835                 840

 Phe Gln Gly Thr Asn Ser Leu Gly Leu Lys Ser Ser Gln Ser Val
                 845                 850                 855

 Gln Ser Ile Arg Pro Pro Tyr Asn Arg Ala Val Ser Leu Asp Ser
                 860                 865                 870

 Pro Val Ser Val Gly Ser Ser Pro Pro Val Lys Asn Ile Ser Ala
                 875                 880                 885

 Phe Pro Met Leu Pro Lys Gln Pro Met Leu Gly Gly Asn Pro Arg
                 890                 895                 900

 Met Met Asp Ser Gln Glu Asn Tyr Gly Ser Ser Met Gly Asp Trp
                 905                 910                 915

 Gly Leu Pro Asn Ser Lys Ala Gly Arg Met Glu Pro Met Asn Ser
                 920                 925                 930

 Asn Ser Met Gly Arg Pro Gly Gly Asp Tyr Asn Thr Ser Leu Pro
                 935                 940                 945

 Arg Pro Ala Leu Gly Gly Ser Ile Pro Thr Leu Pro Leu Arg Ser
                 950                 955                 960

 Asn Ser Ile Pro Gly Ala Arg Pro Val Leu Gln Gln Gln Gln Gln
                 965                 970                 975

 Met Leu Gln Met Arg Pro Gly Glu Ile Pro Met Gly Met Gly Ala
                 980                 985                 990

 Asn Pro Tyr Gly Gln Ala Ala Ala Ser Asn Gln Leu Gly Ser Trp
                 995                1000                1005

 Pro Asp Gly Met Leu Ser Met Glu Gln Val Ser His Gly Thr Gln
                1010                1015                1020

 Asn Arg Pro Leu Leu Arg Asn Ser Leu Asp Asp Leu Val Gly Pro
                1025                1030                1035

 Pro Ser Asn Leu Glu Gly Gln Ser Asp Glu Arg Ala Leu Leu Asp
                1040                1045                1050

 Gln Leu His Thr Leu Leu Ser Asn Thr Asp Ala Thr Gly Leu Glu
                1055                1060                1065

 Glu Ile Asp Arg Ala Leu Gly Ile Pro Glu Leu Val Asn Gln Gly
                1070                1075                1080

 Gln Ala Leu Glu Pro Lys Gln Asp Ala Phe Gln Gly Gln Glu Ala
                1085                1090                1095

 Ala Val Met Met Asp Gln Lys Ala Gly Leu Tyr Gly Gln Thr Tyr
                1100                1105                1110

 Pro Ala Gln Gly Pro Pro Met Gln Gly Gly Phe His Leu Gln Gly
                1115                1120                1125

 Gln Ser Pro Ser Phe Asn Ser Met Met Asn Gln Met Asn Gln Gln
                1130                1135                1140

 Gly Asn Phe Pro Leu Gln Gly Met His Pro Arg Ala Asn Ile Met
                1145                1150                1155

 Arg Pro Arg Thr Asn Thr Pro Lys Gln Leu Arg Met Gln Leu Gln
                1160                1165                1170

 Gln Arg Leu Gln Gly Gln Gln Phe Leu Asn Gln Ser Arg Gln Ala
                1175                1180                1185

 Leu Glu Leu Lys Met Glu Asn Pro Thr Ala Gly Gly Ala Ala Val
                1190                1195                1200

 Met Arg Pro Met Met Gln Pro Gln Gln Gly Phe Leu Asn Ala Gln
                1205                1210                1215

 Met Val Ala Gln Arg Ser Arg Glu Leu Leu Ser His His Phe Arg
                1220                1225                1230

 Gln Gln Arg Val Ala Met Met Met Gln Gln Gln Gln Gln Gln Gln
                1235                1240                1245

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                1250                1255                1260

 Gln Gln Gln Gln Thr Gln Ala Phe Ser Pro Pro Pro Asn Val Thr
                1265                1270                1275

 Ala Ser Pro Ser Met Asp Gly Leu Leu Ala Gly Pro Thr Met Pro
                1280                1285                1290

 Gln Ala Pro Pro Gln Gln Phe Pro Tyr Gln Pro Asn Tyr Gly Met
                1295                1300                1305

 Gly Gln Gln Pro Asp Pro Ala Phe Gly Arg Val Ser Ser Pro Pro
                1310                1315                1320

 Asn Ala Met Met Ser Ser Arg Met Gly Pro Ser Gln Asn Pro Met
                1325                1330                1335

 Met Gln His Pro Gln Ala Ala Ser Ile Tyr Gln Ser Ser Glu Met
                1340                1345                1350

 Lys Gly Trp Pro Ser Gly Asn Leu Ala Arg Asn Ser Ser Phe Ser
                1355                1360                1365

 Gln Gln Gln Phe Ala His Gln Gly Asn Pro Ala Val Tyr Ser Met
                1370                1375                1380

 Val His Met Asn Gly Ser Ser Gly His Met Gly Gln Met Asn Met
                1385                1390                1395

 Asn Pro Met Pro Met Ser Gly Met Pro Met Gly Pro Asp Gln Lys
                1400                1405                1410

 Tyr Cys


<210> 1921
<211> 7994
<212> DNA
<213> Homo sapien

<400> 1921
 ctccacagcg acggcggcgg ctgcggctta gtcggtggcg gccggcggcg 50

 gctgcgggct gagcggcgag tttccgattt aaagctgagc tgcgaggaaa 100

 atggcggcgg gaggatcaaa atacttgctg gatggtggac tcagagacca 150

 ataaaaataa actgcttgaa catcctttga ctggttagcc agttgctgat 200

 gtatattcaa gatgagtgga ttaggagaaa acttggatcc actggccagt 250

 gattcacgaa aacgcaaatt gccatgtgat actccaggac aaggtcttac 300

 ctgcagtggt gaaaaacgga gacgggagca ggaaagtaaa tatattgaag 350

 aattggctga gctgatatct gccaatctta gtgatattga caatttcaat 400

 gtcaaaccag ataaatgtgc gattttaaag gaaacagtaa gacagatacg 450

 tcaaataaaa gagcaaggaa aaactatttc caatgatgat gatgttcaaa 500

 aagccgatgt atcttctaca gggcagggag ttattgataa agactcctta 550

 ggaccgcttt tacttcaggc attggatggt ttcctatttg tggtgaatcg 600

 agacggaaac attgtatttg tatcagaaaa tgtcacacaa tacctgcaat 650

 ataagcaaga ggacctggtt aacacaagtg tttacaatat cttacatgaa 700

 gaagacagaa aggattttct taagaattta ccaaaatcta cagttaatgg 750

 agtttcctgg acaaatgaga cccaaagaca aaaaagccat acatttaatt 800

 gccgtatgtt gatgaaaaca ccacatgata ttctggaaga cataaacgcc 850

 agtcctgaaa tgcgccagag atatgaaaca atgcagtgct ttgccctgtc 900

 tcagccacga gctatgatgg aggaagggga agatttgcaa tcttgtatga 950

 tctgtgtggc acgccgcatt actacaggag aaagaacatt tccatcaaac 1000

 cctgagagct ttattaccag acatgatctt tcaggaaagg ttgtcaatat 1050

 agatacaaat tcactgagat cctccatgag gcctggcttt gaagatataa 1100

 tccgaaggtg tattcagaga ttttttagtc taaatgatgg gcagtcatgg 1150

 tcccagaaac gtcactatca agaagcttat cttaatggcc atgccagaaa 1200

 ccccagtata tcgattctcg ttggctgatg gaactatagt gactgcacag 1250

 acaaaaagca aactcttccg aaatcctgta acaaatgatc gacatggctt 1300

 tgtctcaacc cacttccttc agagagaaca gaatggatat agaccaaacc 1350

 caaatcctgt tggacaaggg attagaccac ctatggctgg atgcaacagt 1400

 tcggtaggcg gcatgagtat gtcgccaaac caaggcttac agatgccgag 1450

 cagcagggcc tatggcttgg cagaccctag caccacaggg cagatgagtg 1500

 gagctaggta tgggggttcc agtaacatag cttcattgac ccctgggcca 1550

 ggcatgcaat caccatcttc ctaccagaac aacaactatg ggctcaacat 1600

 gagtagcccc ccacatggga gtcctggtct tgccccaaac cagcagaata 1650

 tcatgatttc tcctcgtaat cgtgggagtc caaagatagc ctcacatcag 1700

 ttttctcctg ttgcaggtgt gcactctccc atggcatctt ctggcaatac 1750

 tgggaaccac agcttttcca gcagctctct cagtgccctg caagccatca 1800

 gtgaaggtgt ggggacttcc cttttatcta ctctgtcatc accaggcccc 1850

 aaattggata actctcccaa tatgaatatt acccaaccaa gtaaagtaag 1900

 caatcaggat tccaagagtc ctctgggctt ttattgcgac caaaatccag 1950

 tggagagttc aatgtgtcag tcaaatagca gagatcacct cagtgacaaa 2000

 gaaagtaagg agagcagtgt tgagggggca gagaatcaaa ggggtccttt 2050

 ggaaagcaaa ggtcataaaa aattactgca gttacttacc tgttcttctg 2100

 atgaccgggg tcattcctcc ttgaccaact cccccctaga ttcaagttgt 2150

 aaagaatctt ctgttagtgt caccagcccc tctggagtct cctcctctac 2200

 atctggagga gtatcctcta catccaatat gcatgggtca ctgttacaag 2250

 agaagcaccg gattttgcac aagttgctgc agaatgggaa ttcaccagct 2300

 gaggtagcca agattactgc agaagccact gggaaagaca ccagcagtat 2350

 aacttcttgt ggggacggaa atgttgtcaa gcaggagcag ctaagtccta 2400

 agaagaagga gaataatgca cttcttagat acctgctgga cagggatgat 2450

 cctagtgatg cactctctaa agaactacag ccccaagtgg aaggagtgga 2500

 taataaaatg agtcagtgca ccagctccac cattcctagc tcaagtcaag 2550

 agaaagaccc taaaattaag acagagacaa gtgaagaggg atctggagac 2600

 ttggataatc tagatgctat tcttggtgat ctgactagtt ctgactttta 2650

 caataattcc atatcctcaa atggtagtca tctggggact aagcaacagg 2700

 tgtttcaagg aactaattct ctgggtttga aaagttcaca gtctgtgcag 2750

 tctattcgtc ctccatataa ccgagcagtg tctctggata gccctgtttc 2800

 tgttggctca agtcctccag taaaaaatat cagtgctttc cccatgttac 2850

 caaagcaacc catgttgggt gggaatccaa gaatgatgga tagtcaggaa 2900

 aattatggct caagtatggg tgggccaaac cgaaatgtga ctgtgactca 2950

 gactccttcc tcaggagact ggggcttacc aaactcaaag gccggcagaa 3000

 tggaacctat gaattcaaac tccatgggaa gaccaggagg agattataat 3050

 acttctttac ccagacctgc actgggtggc tctattccca cattgcctct 3100

 tcggtctaat agcataccag gtgcgagacc agtattgcaa cagcagcagc 3150

 agatgcttca aatgaggcct ggtgaaatcc ccatgggaat gggggctaat 3200

 ccctatggcc aagcagcagc atctaaccaa ctgggttcct ggcccgatgg 3250

 catgttgtcc atggaacaag tttctcatgg cactcaaaat aggcctcttc 3300

 ttaggaattc cctggatgat cttgttgggc caccttccaa cctggaaggc 3350

 cagagtgacg aaagagcatt attggaccag ctgcacactc ttctcagcaa 3400

 cacagatgcc acaggcctgg aagaaattga cagagctttg ggcattcctg 3450

 aacttgtcaa tcagggacag gcattagagc ccaaacagga tgctttccaa 3500

 ggccaagaag cagcagtaat gatggatcag aaggcaggat tatatggaca 3550

 gacataccca gcacaggggc ctccaatgca aggaggcttt catcttcagg 3600

 gacaatcacc atcttttaac tctatgatga atcagatgaa ccagcaaggc 3650

 aattttcctc tccaaggaat gcacccacga gccaacatca tgagaccccg 3700

 gacaaacacc cccaagcaac ttagaatgca gcttcagcag aggctgcagg 3750

 gccagcagtt tttgaatcag agccgacagg cacttgaatt gaaaatggaa 3800

 aaccctactg ctggtggtgc tgcggtgatg aggcctatga tgcagcccca 3850

 ggtgagctcc cagcagggtt ttcttaatgc tcaaatggtc gcccaacgca 3900

 gcagagagct gctaagtcat cacttccgac aacagagggt ggctatgatg 3950

 atgcagcagc agcaacagca gcagcagcag cagcagcagc agcagcagca 4000

 acagcaacag caacagcagc aacagcagca aacccaggcc ttcagcccac 4050

 ctcctaatgt gactgcttcc cccagcatgg atgggctttt ggcaggaccc 4100

 acaatgccac aagctcctcc gcaacagttt ccatatcaac caaattatgg 4150

 aatgggacaa caaccagatc cagcctttgg tcgagtgtct agtcctccca 4200

 atgcaatgat gtcgtcaaga atgggtccct cccagaatcc catgatgcaa 4250

 cacccgcagg ctgcatccat ctatcagtcc tcagaaatga agggctggcc 4300

 atcaggaaat ttggccagga acagctcctt ttcccagcag cagtttgccc 4350

 accaggggaa tcctgcagtg tatagtatgg tgcacatgaa tggcagcagt 4400

 ggtcacatgg gacagatgaa catgaacccc atgcccatgt ctggcatgcc 4450

 tatgggtcct gatcagaaat actgctgaca tctctgcacc aggacctctt 4500

 aaggaaacca ctgtacaaat gacactgcac taggattatt gggaaggaat 4550

 cattgttcca ggcatccatc ttggaagaaa ggaccagctt tgagctccat 4600

 caagggtatt ttaagtgatg tcatttgagc aggactggat tttaagccga 4650

 agggcaatat ctacgtgttt ttcccccctc cttctgctgt gtatcatggt 4700

 gttcaaaaca gaaatgtttt ttggcattcc acctcctagg gatataattc 4750

 tggagacatg gagtgttact gatcataaaa cttttgtgtc acttttttct 4800

 gccttgctag ccaaaatctc ttaaatacac gtaggtgggc cagagaacat 4850

 tggaagaatc aagagagatt agaatatctg gtttctctag ttgcagtatt 4900

 ggacaaagag catagtccca gccttcaggt gtagtagttc tgtgttgacc 4950

 ctttgtccag tggaattggt gattctgaat tgtcctttac taatggtgtt 5000

 gagttgctct gtccctatta tttgccctag gctttctcct aatgaaggtt 5050

 ttcatttgcc attcatgtcc tgtaatactt cacctccagg aactgtcatg 5100

 gatgtccaaa tggctttgca gaaaggaaat gagatgacag tatttaatcg 5150

 cagcagtagc aaacttttca catgctaatg tgcagctgag tgcactttat 5200

 ttaaaaagaa tggataaatg caatattctt gaggtcttga gggaatagtg 5250

 aaacacattc ctggtttttg cctacactta cgtgttagac aagaactatg 5300

 attttttttt ttaaagtact ggtgtcaccc tttgcctata tggtagagca 5350

 ataatgcttt ttaaaaataa acttctgaaa acccaaggcc aggtactgca 5400

 ttctgaatca gaatctcgca gtgtttctgt gaatagattt ttttgtaaat 5450

 atgaccttta agatattgta ttatgtaaaa tatgtatata cctttttttg 5500

 taggtcacaa caactcattt ttacagagtt tgtgaagcta aatatttaac 5550

 attgttgatt tcagtaagct gtgtggtgag gctaccagtg gaagagacat 5600

 cccttgactt ttgtggcctg ggggaggggt agtgctccac agcttttcct 5650

 tccccacccc ccagccttag atgcctcgct cttttcaatc tcttaatcta 5700

 aatgcttttt aaagagatta tttgtttaga tgtaggcatt ttaatttttt 5750

 aaaaattcct ctaccagaac taagcacttt gttaatttgg ggggaaagaa 5800

 tagatatggg gaaataaact taaaaaaaaa tcaggaattt aaaaaaacga 5850

 gcaatttgaa gagaatcttt tggattttaa gcagtccgaa ataatagcaa 5900

 ttcatgggct gtgtgtgtgt gtgtatgtgt gtgtgtgtgt gtgtgtatgt 5950

 ttaattatgt taccttttca tcccctttag gagcgttttc agattttggt 6000

 tgctaagacc tgaatcccat attgagatct cgagtagaat ccttggtgtg 6050

 gtttctggtg tctgctcagc tgtcccctca ttctactaat gtgatgcttt 6100

 cattatgtcc ctgtggatta gaatagtgtc agttatttct taagtaactc 6150

 agtacccaga acagccagtt ttactgtgat tcagagccac agtctaactg 6200

 agcacctttt aaacccctcc ctcttctgcc ccctaccact tttctgctgt 6250

 tgcctctctt tgacacctgt tttagtcagt tgggaggaag ggaaaaatca 6300

 agtttaattc cctttatctg ggttaattca tttggttcaa atagttgacg 6350

 gaattgggtt tctgaatgtc tgtgaatttc agaggtctct gctagccttg 6400

 gtatcatttt ctagcaataa ctgagagcca gttaatttta agaatttcac 6450

 acatttagcc aatctttcta gatgtctctg aaggtaagat catttaatat 6500

 ctttgatatg cttacgagta agtgaatcct gattatttcc agacccacca 6550

 ccagagtgga tcttattttc aaagcagtat agacaattat gagtttgccc 6600

 tctttcccct accaagttca aaatatatct aagaaagatt gtaaatccga 6650

 aaacttccat tgtagtggcc tgtgcttttc agatagtata ctctcctgtt 6700

 tggagacaga ggaagaacca ggtcagtctg tctctttttc agctcaattg 6750

 tatctgaccc ttctttaagt tatgtgtgtg gggagaaata gaatggtgct 6800

 cttatctttc ttgactttaa aaaaattatt aaaaacaaaa aaaaaataaa 6850

 tttttttgca atcctttcct cagacctggc tccaggctaa ctggaaggca 6900

 gcactctctt ttttatatag tagaaaaatg aagtttatta taagttttta 6950

 tattttctac ttgttcattt ggtgcaaact caagatttct tttaataggt 7000

 gcagtctttg agataatttg tttttacctg tattgccctt tatctttttt 7050

 aggtaattct ttgtactcct gctgtctacc tctcctcaca ccccagcacc 7100

 ccccattttt tcaaaccttg gtatctgttg ggtgaacagt ataatctttt 7150

 catctgcttt tagaatgtgg gatatttcca gtacctactt tttttttttt 7200

 tttttgctga atccaaagat atataaataa aatatatata ttttataaag 7250

 atcagaatga tataaaggag atacatgttt cttcctttaa aaaataaacg 7300

 gaagttacat tgttaatgtt catattatga tgccactttt ctaaactgca 7350

 tctggattga aaggtgtaaa tatcaataac agtgctactt agttatcagt 7400

 atttaatatc tgaggtgagt tgggggtatc tatattaggg gtagggtatt 7450

 acagaagata attggcttga tgtcctagaa gttctttgat ccagaggtgg 7500

 gtgcagctga aagtaaacag aatggattgc cagttacatg tatgcctgcc 7550

 cagttccctt tttatttgca gaagctgtga gttttgttca caattaggtt 7600

 cctaggagca aaacctcaag gattgattta ttgttttcaa ctccaaggca 7650

 cactgttaat aaacgagcag ggtgttttct ctcttccttt ctaatatatg 7700

 gagtttcgaa gaataaaata tgagagcaat atttaaattc tcaggaattg 7750

 acttatactc ttgagaatga attcagtttc aatcaagttt acattatgtt 7800

 gcttaaaaaa atagaaatta ttctttatct tgcaaagaat tgaaaccaca 7850

 tgaaatgact tatgggggat ggtgagctgt gactgctttg ctgaccattt 7900

 tggatgtcat tgtaaataaa ggtttctatt taaaattgga gcctaaagag 7950

 tttttttttt ttgaatccct gtggggttaa gggtacagga aggt 7994

<210> 1922
<211> 1421
<212> PRT
<213> Homo sapien

<400> 1922
 Met Ser Gly Leu Gly Glu Asn Leu Asp Pro Leu Ala Ser Asp Ser
   1               5                  10                  15

 Arg Lys Arg Lys Leu Pro Cys Asp Thr Pro Gly Gln Gly Leu Thr
                  20                  25                  30

 Cys Ser Gly Glu Lys Arg Arg Arg Glu Gln Glu Ser Lys Tyr Ile
                  35                  40                  45

 Glu Glu Leu Ala Glu Leu Ile Ser Ala Asn Leu Ser Asp Ile Asp
                  50                  55                  60

 Asn Phe Asn Val Lys Pro Asp Lys Cys Ala Ile Leu Lys Glu Thr
                  65                  70                  75

 Val Arg Gln Ile Arg Gln Ile Lys Glu Gln Gly Lys Thr Ile Ser
                  80                  85                  90

 Asn Asp Asp Asp Val Gln Lys Ala Asp Val Ser Ser Thr Gly Gln
                  95                 100                 105

 Gly Val Ile Asp Lys Asp Ser Leu Gly Pro Leu Leu Leu Gln Ala
                 110                 115                 120

 Leu Asp Gly Phe Leu Phe Val Val Asn Arg Asp Gly Asn Ile Val
                 125                 130                 135

 Phe Val Ser Glu Asn Val Thr Gln Tyr Leu Gln Tyr Lys Gln Glu
                 140                 145                 150

 Asp Leu Val Asn Thr Ser Val Tyr Asn Ile Leu His Glu Glu Asp
                 155                 160                 165

 Arg Lys Asp Phe Leu Lys Asn Leu Pro Lys Ser Thr Val Asn Gly
                 170                 175                 180

 Val Ser Trp Thr Asn Glu Thr Gln Arg Gln Lys Ser His Thr Phe
                 185                 190                 195

 Asn Cys Arg Met Leu Met Lys Thr Pro His Asp Ile Leu Glu Asp
                 200                 205                 210

 Ile Asn Ala Ser Pro Glu Met Arg Gln Arg Tyr Glu Thr Met Gln
                 215                 220                 225

 Cys Phe Ala Leu Ser Gln Pro Arg Ala Met Met Glu Glu Gly Glu
                 230                 235                 240

 Asp Leu Gln Ser Cys Met Ile Cys Val Ala Arg Arg Ile Thr Thr
                 245                 250                 255

 Gly Glu Arg Thr Phe Pro Ser Asn Pro Glu Ser Phe Ile Thr Arg
                 260                 265                 270

 His Asp Leu Ser Gly Lys Val Val Asn Ile Asp Thr Asn Ser Leu
                 275                 280                 285

 Arg Ser Ser Met Arg Pro Gly Phe Glu Asp Ile Ile Arg Arg Cys
                 290                 295                 300

 Ile Gln Arg Phe Phe Ser Leu Asn Asp Gly Gln Ser Trp Ser Gln
                 305                 310                 315

 Lys Arg His Tyr Gln Glu Ala Tyr Leu Asn Gly His Ala Arg Asn
                 320                 325                 330

 Pro Ser Ile Ser Ile Leu Val Gly Asp Gly Thr Ile Val Thr Ala
                 335                 340                 345

 Gln Thr Lys Ser Lys Leu Phe Arg Asn Pro Val Thr Asn Asp Arg
                 350                 355                 360

 His Gly Phe Val Ser Thr His Phe Leu Gln Arg Glu Gln Asn Gly
                 365                 370                 375

 Tyr Arg Pro Asn Pro Asn Pro Val Gly Gln Gly Ile Arg Pro Pro
                 380                 385                 390

 Met Ala Gly Cys Asn Ser Ser Val Gly Gly Met Ser Met Ser Pro
                 395                 400                 405

 Asn Gln Gly Leu Gln Met Pro Ser Ser Arg Ala Tyr Gly Leu Ala
                 410                 415                 420

 Asp Pro Ser Thr Thr Gly Gln Met Ser Gly Ala Arg Tyr Gly Gly
                 425                 430                 435

 Ser Ser Asn Ile Ala Ser Leu Thr Pro Gly Pro Gly Met Gln Ser
                 440                 445                 450

 Pro Ser Ser Tyr Gln Asn Asn Asn Tyr Gly Leu Asn Met Ser Ser
                 455                 460                 465

 Pro Pro His Gly Ser Pro Gly Leu Ala Pro Asn Gln Gln Asn Ile
                 470                 475                 480

 Met Ile Ser Pro Arg Asn Arg Gly Ser Pro Lys Ile Ala Ser His
                 485                 490                 495

 Gln Phe Ser Pro Val Ala Gly Val His Ser Pro Met Ala Ser Ser
                 500                 505                 510

 Gly Asn Thr Gly Asn His Ser Phe Ser Ser Ser Ser Leu Ser Ala
                 515                 520                 525

 Leu Gln Ala Ile Ser Glu Gly Val Gly Thr Ser Leu Leu Ser Thr
                 530                 535                 540

 Leu Ser Ser Pro Gly Pro Lys Leu Asp Asn Ser Pro Asn Met Asn
                 545                 550                 555

 Ile Thr Gln Pro Ser Lys Val Ser Asn Gln Asp Ser Lys Ser Pro
                 560                 565                 570

 Leu Gly Phe Tyr Cys Asp Gln Asn Pro Val Glu Ser Ser Met Cys
                 575                 580                 585

 Gln Ser Asn Ser Arg Asp His Leu Ser Asp Lys Glu Ser Lys Glu
                 590                 595                 600

 Ser Ser Val Glu Gly Ala Glu Asn Gln Arg Gly Pro Leu Glu Ser
                 605                 610                 615

 Lys Gly His Lys Lys Leu Leu Gln Leu Leu Thr Cys Ser Ser Asp
                 620                 625                 630

 Asp Arg Gly His Ser Ser Leu Thr Asn Ser Pro Leu Asp Ser Ser
                 635                 640                 645

 Cys Lys Glu Ser Ser Val Ser Val Thr Ser Pro Ser Gly Val Ser
                 650                 655                 660

 Ser Ser Thr Ser Gly Gly Val Ser Ser Thr Ser Asn Met His Gly
                 665                 670                 675

 Ser Leu Leu Gln Glu Lys His Arg Ile Leu His Lys Leu Leu Gln
                 680                 685                 690

 Asn Gly Asn Ser Pro Ala Glu Val Ala Lys Ile Thr Ala Glu Ala
                 695                 700                 705

 Thr Gly Lys Asp Thr Ser Ser Ile Thr Ser Cys Gly Asp Gly Asn
                 710                 715                 720

 Val Val Lys Gln Glu Gln Leu Ser Pro Lys Lys Lys Glu Asn Asn
                 725                 730                 735

 Ala Leu Leu Arg Tyr Leu Leu Asp Arg Asp Asp Pro Ser Asp Ala
                 740                 745                 750

 Leu Ser Lys Glu Leu Gln Pro Gln Val Glu Gly Val Asp Asn Lys
                 755                 760                 765

 Met Ser Gln Cys Thr Ser Ser Thr Ile Pro Ser Ser Ser Gln Glu
                 770                 775                 780

 Lys Asp Pro Lys Ile Lys Thr Glu Thr Ser Glu Glu Gly Ser Gly
                 785                 790                 795

 Asp Leu Asp Asn Leu Asp Ala Ile Leu Gly Asp Leu Thr Ser Ser
                 800                 805                 810

 Asp Phe Tyr Asn Asn Ser Ile Ser Ser Asn Gly Ser His Leu Gly
                 815                 820                 825

 Thr Lys Gln Gln Val Phe Gln Gly Thr Asn Ser Leu Gly Leu Lys
                 830                 835                 840

 Ser Ser Gln Ser Val Gln Ser Ile Arg Pro Pro Tyr Asn Arg Ala
                 845                 850                 855

 Val Ser Leu Asp Ser Pro Val Ser Val Gly Ser Ser Pro Pro Val
                 860                 865                 870

 Lys Asn Ile Ser Ala Phe Pro Met Leu Pro Lys Gln Pro Met Leu
                 875                 880                 885

 Gly Gly Asn Pro Arg Met Met Asp Ser Gln Glu Asn Tyr Gly Ser
                 890                 895                 900

 Ser Met Gly Gly Pro Asn Arg Asn Val Thr Val Thr Gln Thr Pro
                 905                 910                 915

 Ser Ser Gly Asp Trp Gly Leu Pro Asn Ser Lys Ala Gly Arg Met
                 920                 925                 930

 Glu Pro Met Asn Ser Asn Ser Met Gly Arg Pro Gly Gly Asp Tyr
                 935                 940                 945

 Asn Thr Ser Leu Pro Arg Pro Ala Leu Gly Gly Ser Ile Pro Thr
                 950                 955                 960

 Leu Pro Leu Arg Ser Asn Ser Ile Pro Gly Ala Arg Pro Val Leu
                 965                 970                 975

 Gln Gln Gln Gln Gln Met Leu Gln Met Arg Pro Gly Glu Ile Pro
                 980                 985                 990

 Met Gly Met Gly Ala Asn Pro Tyr Gly Gln Ala Ala Ala Ser Asn
                 995                1000                1005

 Gln Leu Gly Ser Trp Pro Asp Gly Met Leu Ser Met Glu Gln Val
                1010                1015                1020

 Ser His Gly Thr Gln Asn Arg Pro Leu Leu Arg Asn Ser Leu Asp
                1025                1030                1035

 Asp Leu Val Gly Pro Pro Ser Asn Leu Glu Gly Gln Ser Asp Glu
                1040                1045                1050

 Arg Ala Leu Leu Asp Gln Leu His Thr Leu Leu Ser Asn Thr Asp
                1055                1060                1065

 Ala Thr Gly Leu Glu Glu Ile Asp Arg Ala Leu Gly Ile Pro Glu
                1070                1075                1080

 Leu Val Asn Gln Gly Gln Ala Leu Glu Pro Lys Gln Asp Ala Phe
                1085                1090                1095

 Gln Gly Gln Glu Ala Ala Val Met Met Asp Gln Lys Ala Gly Leu
                1100                1105                1110

 Tyr Gly Gln Thr Tyr Pro Ala Gln Gly Pro Pro Met Gln Gly Gly
                1115                1120                1125

 Phe His Leu Gln Gly Gln Ser Pro Ser Phe Asn Ser Met Met Asn
                1130                1135                1140

 Gln Met Asn Gln Gln Gly Asn Phe Pro Leu Gln Gly Met His Pro
                1145                1150                1155

 Arg Ala Asn Ile Met Arg Pro Arg Thr Asn Thr Pro Lys Gln Leu
                1160                1165                1170

 Arg Met Gln Leu Gln Gln Arg Leu Gln Gly Gln Gln Phe Leu Asn
                1175                1180                1185

 Gln Ser Arg Gln Ala Leu Glu Leu Lys Met Glu Asn Pro Thr Ala
                1190                1195                1200

 Gly Gly Ala Ala Val Met Arg Pro Met Met Gln Pro Gln Val Ser
                1205                1210                1215

 Ser Gln Gln Gly Phe Leu Asn Ala Gln Met Val Ala Gln Arg Ser
                1220                1225                1230

 Arg Glu Leu Leu Ser His His Phe Arg Gln Gln Arg Val Ala Met
                1235                1240                1245

 Met Met Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                1250                1255                1260

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Thr Gln
                1265                1270                1275

 Ala Phe Ser Pro Pro Pro Asn Val Thr Ala Ser Pro Ser Met Asp
                1280                1285                1290

 Gly Leu Leu Ala Gly Pro Thr Met Pro Gln Ala Pro Pro Gln Gln
                1295                1300                1305

 Phe Pro Tyr Gln Pro Asn Tyr Gly Met Gly Gln Gln Pro Asp Pro
                1310                1315                1320

 Ala Phe Gly Arg Val Ser Ser Pro Pro Asn Ala Met Met Ser Ser
                1325                1330                1335

 Arg Met Gly Pro Ser Gln Asn Pro Met Met Gln His Pro Gln Ala
                1340                1345                1350

 Ala Ser Ile Tyr Gln Ser Ser Glu Met Lys Gly Trp Pro Ser Gly
                1355                1360                1365

 Asn Leu Ala Arg Asn Ser Ser Phe Ser Gln Gln Gln Phe Ala His
                1370                1375                1380

 Gln Gly Asn Pro Ala Val Tyr Ser Met Val His Met Asn Gly Ser
                1385                1390                1395

 Ser Gly His Met Gly Gln Met Asn Met Asn Pro Met Pro Met Ser
                1400                1405                1410

 Gly Met Pro Met Gly Pro Asp Gln Lys Tyr Cys
                1415                1420

<210> 1923
<211> 6754
<212> DNA
<213> Homo sapien

<400> 1923
 gtcgacgtgg cggccggcgg cggctgcggg ctgagcggcg agtttccgat 50

 ttaaagctga gctgcgagga aaatggcggc gggaggatca aaatacttgc 100

 tggatggtgg actcagagac caataaaaat aaactgcttg aacatccttt 150

 gactggttag ccagttgctg atgtatattc aagatgagtg gattaggaga 200

 aaacttggat ccactggcca gtgattcacg aaaacgcaaa ttgccatgtg 250

 atactccagg acaaggtctt acctgcagtg gtgaaaaacg gagacgggag 300

 caggaaagta aatatattga agaattggct gagctgatat ctgccaatct 350

 tagtgatatt gacaatttca atgtcaaacc agataaatgt gcgattttaa 400

 aggaaacagt aagacagata cgtcaaataa aagagcaagg aaaaactatt 450

 tccaatgatg atgatgttca aaaagccgat gtatcttcta cagggcaggg 500

 agttattgat aaagactcct taggaccgct tttacttcag gcattggatg 550

 gtttcctatt tgtggtgaat cgagacggaa acattgtatt tgtatcagaa 600

 aatgtcacac aatacctgca atataagcaa gaggacctgg ttaacacaag 650

 tgtttacaat atcttacatg aagaagacag aaaggatttt cttaagaatt 700

 taccaaaatc tacagttaat ggagtttcct ggacaaatga gacccaaaga 750

 caaaaaagcc atacatttaa ttgccgtatg ttgatgaaaa caccacatga 800

 tattctggaa gacataaacg ccagtcctga aatgcgccag agatatgaaa 850

 caatgcagtg ctttgccctg tctcagccac gagctatgat ggaggaaggg 900

 gaagatttgc aatcttgtat gatctgtgtg gcacgccgca ttactacagg 950

 agaaagaaca tttccatcaa accctgagag ctttattacc agacatgatc 1000

 tttcaggaaa ggttgtcaat atagatacaa attcactgag atcctccatg 1050

 aggcctggct ttgaagatat aatccgaagg tgtattcaga gattttttag 1100

 tctaaatgat gggcagtcat ggtcccagaa acgtcactat caagaagtta 1150

 ccagtgatgg gatattttcc ccaacagctt atcttaatgg ccatgcagaa 1200

 accccagtat atcgattctc gttggctgat ggaactatag tgactgcaca 1250

 gacaaaaagc aaactcttcc gaaatcctgt aacaaatgat cgacatggct 1300

 ttgtctcaac ccacttcctt cagagagaac agaatggata tagaccaaac 1350

 ccaaatcctg ttggacaagg gattagacca cctatggctg gatgcaacag 1400

 ttcggtaggc ggcatgagta tgtcgccaaa ccaaggctta cagatgccga 1450

 gcagcagggc ctatggcttg gcagacccta gcaccacagg gcagatgagt 1500

 ggagctaggt atgggggttc cagtaacata gcttcattga cccctgggcc 1550

 aggcatgcaa tcaccatctt cctaccagaa caacaactat aggctcaaca 1600

 tgagtagccc cccacatggg agtcctggtc ttgccccaaa ccagcagaat 1650

 atcatgattt ctcctcgtaa tcgtgggagt ccaaagatag cctcacatca 1700

 gttttctcct gttgcaggtg tgcactctcc catggcatct tctggcaata 1750

 ctgggaacca cagcttttcc agcagctctc tcagtgccct gcaagccatc 1800

 agtgaaggtg tggggacttc ccttttatct actctgtcat caccaggccc 1850

 caaattggat aactctccca atatgaatat tacccaacca agtaaagtaa 1900

 gcaatcagga ttccaagagt cctctgggct tttattgcga ccaaaatcca 1950

 gtggagagtt caatgtgtca gtcaaatagc agagatcacc tcagtgacaa 2000

 agaaagtaag gagagcagtg ttgagggggc agagaatcaa aggggtcctt 2050

 tggaaagcaa aggtcataaa aaattactgc agttacttac ctgttcttct 2100

 gatgaccggg gtcattcctc cttgaccaac tcccccctag attcaagttg 2150

 taaagaatct tctgttagtg tcaccagccc ctctggagtc tcctcctcta 2200

 catctggagg agtatcctct acatccaata tgcatgggtc actgttacaa 2250

 gagaagcacc ggattttgca caagttgctg cagaatggga attcaccagc 2300

 tgaggtagcc aagattactg cagaagccac tgggaaagac accagcagta 2350

 taacttcttg tggggacgga aatgttgtca agcaggagca gctaagtcct 2400

 aagaagaagg agaataatgc acttcttaga tacctgctgg acagggatga 2450

 tcctagtgat gcactctcta aagaactaca gccccaagtg gaaggagtgg 2500

 ataataaaat gagtcagtgc accagctcca ccattcctag ctcaagtcaa 2550

 gagaaagacc ctaaaattaa gacagagaca agtgaagagg gatctggaga 2600

 cttggataat ctagatgcta ttcttggtga tctgactagt tctgactttt 2650

 acaataattc catatcctca aatggtagtc atctggggac taagcaacag 2700

 gtgtttcaag gaactaattc tctgggtttg aaaagttcac agtctgtgca 2750

 gtctattcgt cctccatata accgagcagt gtctctggat agccctgttt 2800

 ctgttggctc aagtcctcca gtaaaaaata tcagtgcttt ccccatgtta 2850

 ccaaagcaac ccatgttggg tgggaatcca agaatgatgg atagtcagga 2900

 aaattatggc tcaagtatgg gagactgggg cttaccaaac tcaaaggccg 2950

 gcagaatgga acctatgaat tcaaactcca tgggaagacc aggaggagat 3000

 tataatactt ctttacccag acctgcactg ggtggctcta ttcccacatt 3050

 gcctcttcgg tctaatagca taccaggtgc gagaccagta ttgcaacagc 3100

 agcagcagat gcttcaaatg aggcctggtg aaatccccat gggaatgggg 3150

 gctaatccct atggccaagc agcagcatct aaccaactgg gttcctggcc 3200

 cgatggcatg ttgtccatgg aacaagtttc tcatggcact caaaataggc 3250

 ctcttcttag gaattccctg gatgatcttg ttgggccacc ttccaacctg 3300

 gaaggccaga gtgacgaaag agcattattg gaccagctgc acactcttct 3350

 cagcaacaca gatgccacag gcctggaaga aattgacaga gctttgggca 3400

 ttcctgaact tgtcaatcag ggacaggcat tagagcccaa acaggatgct 3450

 ttccaaggcc aagaagcagc agtaatgatg gatcagaagg caggattata 3500

 tggacagaca tacccagcac aggggcctcc aatgcaagga ggctttcatc 3550

 ttcagggaca atcaccatct tttaactcta tgatgaatca gatgaaccag 3600

 caaggcaatt ttcctctcca aggaatgcac ccacgagcca acatcatgag 3650

 accccggaca aacaccccca agcaacttag aatgcagctt cagcagaggc 3700

 tgcagggcca gcagtttttg aatcagagcc gacaggcact tgaattgaaa 3750

 atggaaaacc ctactgctgg tggtgctgcg gtgatgaggc ctatgatgca 3800

 gccccagcag ggttttctta atgctcaaat ggtcgcccaa cgcagcagag 3850

 agctgctaag tcatcacttc cgacaacaga gggtggctat gatgatgcag 3900

 cagcagcaac agcagcagca gcagcagcag cagcagcaac agcaacagca 3950

 acagcaacag cagcaacagc agcaaaccca ggccttcagc ccacctccta 4000

 atgtgactgc ttcccccagc atggatgggc ttttggcagg acccacaatg 4050

 ccacaagctc ctccgcaaca gtttccatat caaccaaatt atggaatggg 4100

 acaacaacca gatccagcct ttggtcgagt gtctagtcct cccaatgcaa 4150

 tgatgtcgtc aagaatgggt ccctcccaga atcccatgat gcaacacccg 4200

 caggctgcat ccatctatca gtcctcagaa atgaagggct ggccatcagg 4250

 aaatttggcc aggaacagct ccttttccca gcagcagttt gcccaccagg 4300

 ggaatcctgc agtgtatagt atggtgcaca tgaatggcag cagtggtcac 4350

 atgggacaga tgaacatgaa ccccatgccc atgtctggca tgcctatggg 4400

 tcctgatcag aaatactgct gacatctctg caccaggacc tcttaaggaa 4450

 accactgtac aaatgacact gcactaggat tattgggaag gaatcattgt 4500

 tccaggcatc catcttggaa gaaaggacca gctttgagct ccatcaaggg 4550

 tattttaagt gatgtcattt gagcaggact ggattttaag ccgaagggca 4600

 atatctacgt gtttttcccc cctccttctg ctgtgtatca tggtgttcaa 4650

 aacagaaatg ttttttggca ttccacctcc tagggatata attctggaga 4700

 catggagtgt tactgatcat aaaacttttg tgtcactttt ttctgccttg 4750

 ctagccaaaa tctcttaaat acacgtaggt gggccagaga acattggaag 4800

 aatcaagaga gattagaata tctggtttct ctagttgcag tattggacaa 4850

 agagcatagt cccagccttc aggtgtagta gttctgtgtt gaccctttgt 4900

 ccagtggaat tggtgattct gaattgtcct ttactaatgg tgttgagttg 4950

 ctctgtccct attatttgcc ctaggctttc tcctaatgaa ggttttcatt 5000

 tgccattcat gtcctgtaat acttcacctc caggaactgt catggatgtc 5050

 caaatggctt tgcagaaagg aaatgagatg acagtattta atcgcagcag 5100

 tagcaaactt ttcacatgct aatgtgcagc tgagtgcact ttatttaaaa 5150

 agaatggata aatgcaatat tcttgaggtc ttgagggaat agtgaaacac 5200

 attcctggtt tttgcctaca cttacgtgtt agacaagaac tatgattttt 5250

 ttttttaaag tactggtgtc accctttgcc tatatggtag agcaataatg 5300

 ctttttaaaa ataaacttct gaaaacccaa ggccaggtac tgcattctga 5350

 atcagaatct cgcagtgttt ctgtgaatag atttttttgt aaatatgacc 5400

 tttaagatat tgtattatgt aaaatatgta tatacctttt tttgtaggtc 5450

 acaacaactc atttttacag agtttgtgaa gctaaatatt taacattgtt 5500

 gatttcagta agctgtgtgg tgaggctacc agtggaagag acatcccttg 5550

 acttttgtgg cctgggggag gggtagtgca ccacagcttt tccttcccca 5600

 ccccccagcc ttagatgcct cgctcttttc aatctcttaa tctaaatgct 5650

 ttttaaagag attatttgtt tagatgtagg cattttaatt ttttaaaaat 5700

 tcctctacca gaactaagca ctttgttaat ttggggggaa agaatagata 5750

 tggggaaata aacttaaaaa aaaatcagga atttaaaaaa aacgagcaat 5800

 ttgaagagaa tcttttggat tttaagcagt ccgaaataat agcaattcat 5850

 gggctgtgtg tgtgtgtgta tgtgtgtgtg tgtgtgtgta tgtttaatta 5900

 tgttaccttt tcatcccctt taggagcgtt ttcagatttt ggttcgtaag 5950

 acctgaatcc catattgaga tctcgagtag aatccttggt gtggtttctg 6000

 gtgtctgctc agctgtcccc tcattctact aatgtgatgc tttcattatg 6050

 tccctgtgga ttagaatagt gtcagttatt tcttaagtaa ctcagtaccc 6100

 agaacagcca gttttactgt gattcagagc cacagtctaa ctgagcacct 6150

 tttaaacccc tccctcttct gccccctacc acttttctgc tgttgcctct 6200

 ctttgacacc tgttttagtc agttgggagg aagggaaaaa tcaagtttaa 6250

 ttccctttat ctgggttaat tcatttggtt caaatagttg acggaattgg 6300

 gtttctgaat gtctgtgaat ttcagaggtc tctgctagcc ttggtatcat 6350

 tttctagcaa taactgagag ccagttaatt ttaagaattt cacacattta 6400

 gccaatcttt ctagatgtct ctgaaggtaa gatcatttaa tatctttgat 6450

 atgcttacga gtaagtgaat cctgattatt tccagaccca ccaccagagt 6500

 ggatcttatt ttcaaagcag tatagacaat tatgagtttg ccctctttcc 6550

 cctaccaagt tcaaaatata tctaagaaag attgtaaatc cgaaaacttc 6600

 cattgtagtg gcctgtgctt ttcagatagt atactctcct gtttggagac 6650

 agaggaagaa ccaggtcagt ctgtctcttt ttcagctcaa ttgtatctga 6700

 cccttcttta agttatgtgt gtggggagaa atagaatggt gctcttatgt 6750

 cgac 6754

<210> 1924
<211> 1412
<212> PRT
<213> Homo sapien

<400> 1924
 Met Ser Gly Leu Gly Glu Asn Leu Asp Pro Leu Ala Ser Asp Ser
   1               5                  10                  15

 Arg Lys Arg Lys Leu Pro Cys Asp Thr Pro Gly Gln Gly Leu Thr
                  20                  25                  30

 Cys Ser Gly Glu Lys Arg Arg Arg Glu Gln Glu Ser Lys Tyr Ile
                  35                  40                  45

 Glu Glu Leu Ala Glu Leu Ile Ser Ala Asn Leu Ser Asp Ile Asp
                  50                  55                  60

 Asn Phe Asn Val Lys Pro Asp Lys Cys Ala Ile Leu Lys Glu Thr
                  65                  70                  75

 Val Arg Gln Ile Arg Gln Ile Lys Glu Gln Gly Lys Thr Ile Ser
                  80                  85                  90

 Asn Asp Asp Asp Val Gln Lys Ala Asp Val Ser Ser Thr Gly Gln
                  95                 100                 105

 Gly Val Ile Asp Lys Asp Ser Leu Gly Pro Leu Leu Leu Gln Ala
                 110                 115                 120

 Leu Asp Gly Phe Leu Phe Val Val Asn Arg Asp Gly Asn Ile Val
                 125                 130                 135

 Phe Val Ser Glu Asn Val Thr Gln Tyr Leu Gln Tyr Lys Gln Glu
                 140                 145                 150

 Asp Leu Val Asn Thr Ser Val Tyr Asn Ile Leu His Glu Glu Asp
                 155                 160                 165

 Arg Lys Asp Phe Leu Lys Asn Leu Pro Lys Ser Thr Val Asn Gly
                 170                 175                 180

 Val Ser Trp Thr Asn Glu Thr Gln Arg Gln Lys Ser His Thr Phe
                 185                 190                 195

 Asn Cys Arg Met Leu Met Lys Thr Pro His Asp Ile Leu Glu Asp
                 200                 205                 210

 Ile Asn Ala Ser Pro Glu Met Arg Gln Arg Tyr Glu Thr Met Gln
                 215                 220                 225

 Cys Phe Ala Leu Ser Gln Pro Arg Ala Met Met Glu Glu Gly Glu
                 230                 235                 240

 Asp Leu Gln Ser Cys Met Ile Cys Val Ala Arg Arg Ile Thr Thr
                 245                 250                 255

 Gly Glu Arg Thr Phe Pro Ser Asn Pro Glu Ser Phe Ile Thr Arg
                 260                 265                 270

 His Asp Leu Ser Gly Lys Val Val Asn Ile Asp Thr Asn Ser Leu
                 275                 280                 285

 Arg Ser Ser Met Arg Pro Gly Phe Glu Asp Ile Ile Arg Arg Cys
                 290                 295                 300

 Ile Gln Arg Phe Phe Ser Leu Asn Asp Gly Gln Ser Trp Ser Gln
                 305                 310                 315

 Lys Arg His Tyr Gln Glu Val Thr Ser Asp Gly Ile Phe Ser Pro
                 320                 325                 330

 Thr Ala Tyr Leu Asn Gly His Ala Glu Thr Pro Val Tyr Arg Phe
                 335                 340                 345

 Ser Leu Ala Asp Gly Thr Ile Val Thr Ala Gln Thr Lys Ser Lys
                 350                 355                 360

 Leu Phe Arg Asn Pro Val Thr Asn Asp Arg His Gly Phe Val Ser
                 365                 370                 375

 Thr His Phe Leu Gln Arg Glu Gln Asn Gly Tyr Arg Pro Asn Pro
                 380                 385                 390

 Asn Pro Val Gly Gln Gly Ile Arg Pro Pro Met Ala Gly Cys Asn
                 395                 400                 405

 Ser Ser Val Gly Gly Met Ser Met Ser Pro Asn Gln Gly Leu Gln
                 410                 415                 420

 Met Pro Ser Ser Arg Ala Tyr Gly Leu Ala Asp Pro Ser Thr Thr
                 425                 430                 435

 Gly Gln Met Ser Gly Ala Arg Tyr Gly Gly Ser Ser Asn Ile Ala
                 440                 445                 450

 Ser Leu Thr Pro Gly Pro Gly Met Gln Ser Pro Ser Ser Tyr Gln
                 455                 460                 465

 Asn Asn Asn Tyr Arg Leu Asn Met Ser Ser Pro Pro His Gly Ser
                 470                 475                 480

 Pro Gly Leu Ala Pro Asn Gln Gln Asn Ile Met Ile Ser Pro Arg
                 485                 490                 495

 Asn Arg Gly Ser Pro Lys Ile Ala Ser His Gln Phe Ser Pro Val
                 500                 505                 510

 Ala Gly Val His Ser Pro Met Ala Ser Ser Gly Asn Thr Gly Asn
                 515                 520                 525

 His Ser Phe Ser Ser Ser Ser Leu Ser Ala Leu Gln Ala Ile Ser
                 530                 535                 540

 Glu Gly Val Gly Thr Ser Leu Leu Ser Thr Leu Ser Ser Pro Gly
                 545                 550                 555

 Pro Lys Leu Asp Asn Ser Pro Asn Met Asn Ile Thr Gln Pro Ser
                 560                 565                 570

 Lys Val Ser Asn Gln Asp Ser Lys Ser Pro Leu Gly Phe Tyr Cys
                 575                 580                 585

 Asp Gln Asn Pro Val Glu Ser Ser Met Cys Gln Ser Asn Ser Arg
                 590                 595                 600

 Asp His Leu Ser Asp Lys Glu Ser Lys Glu Ser Ser Val Glu Gly
                 605                 610                 615

 Ala Glu Asn Gln Arg Gly Pro Leu Glu Ser Lys Gly His Lys Lys
                 620                 625                 630

 Leu Leu Gln Leu Leu Thr Cys Ser Ser Asp Asp Arg Gly His Ser
                 635                 640                 645

 Ser Leu Thr Asn Ser Pro Leu Asp Ser Ser Cys Lys Glu Ser Ser
                 650                 655                 660

 Val Ser Val Thr Ser Pro Ser Gly Val Ser Ser Ser Thr Ser Gly
                 665                 670                 675

 Gly Val Ser Ser Thr Ser Asn Met His Gly Ser Leu Leu Gln Glu
                 680                 685                 690

 Lys His Arg Ile Leu His Lys Leu Leu Gln Asn Gly Asn Ser Pro
                 695                 700                 705

 Ala Glu Val Ala Lys Ile Thr Ala Glu Ala Thr Gly Lys Asp Thr
                 710                 715                 720

 Ser Ser Ile Thr Ser Cys Gly Asp Gly Asn Val Val Lys Gln Glu
                 725                 730                 735

 Gln Leu Ser Pro Lys Lys Lys Glu Asn Asn Ala Leu Leu Arg Tyr
                 740                 745                 750

 Leu Leu Asp Arg Asp Asp Pro Ser Asp Ala Leu Ser Lys Glu Leu
                 755                 760                 765

 Gln Pro Gln Val Glu Gly Val Asp Asn Lys Met Ser Gln Cys Thr
                 770                 775                 780

 Ser Ser Thr Ile Pro Ser Ser Ser Gln Glu Lys Asp Pro Lys Ile
                 785                 790                 795

 Lys Thr Glu Thr Ser Glu Glu Gly Ser Gly Asp Leu Asp Asn Leu
                 800                 805                 810

 Asp Ala Ile Leu Gly Asp Leu Thr Ser Ser Asp Phe Tyr Asn Asn
                 815                 820                 825

 Ser Ile Ser Ser Asn Gly Ser His Leu Gly Thr Lys Gln Gln Val
                 830                 835                 840

 Phe Gln Gly Thr Asn Ser Leu Gly Leu Lys Ser Ser Gln Ser Val
                 845                 850                 855

 Gln Ser Ile Arg Pro Pro Tyr Asn Arg Ala Val Ser Leu Asp Ser
                 860                 865                 870

 Pro Val Ser Val Gly Ser Ser Pro Pro Val Lys Asn Ile Ser Ala
                 875                 880                 885

 Phe Pro Met Leu Pro Lys Gln Pro Met Leu Gly Gly Asn Pro Arg
                 890                 895                 900

 Met Met Asp Ser Gln Glu Asn Tyr Gly Ser Ser Met Gly Asp Trp
                 905                 910                 915

 Gly Leu Pro Asn Ser Lys Ala Gly Arg Met Glu Pro Met Asn Ser
                 920                 925                 930

 Asn Ser Met Gly Arg Pro Gly Gly Asp Tyr Asn Thr Ser Leu Pro
                 935                 940                 945

 Arg Pro Ala Leu Gly Gly Ser Ile Pro Thr Leu Pro Leu Arg Ser
                 950                 955                 960

 Asn Ser Ile Pro Gly Ala Arg Pro Val Leu Gln Gln Gln Gln Gln
                 965                 970                 975

 Met Leu Gln Met Arg Pro Gly Glu Ile Pro Met Gly Met Gly Ala
                 980                 985                 990

 Asn Pro Tyr Gly Gln Ala Ala Ala Ser Asn Gln Leu Gly Ser Trp
                 995                1000                1005

 Pro Asp Gly Met Leu Ser Met Glu Gln Val Ser His Gly Thr Gln
                1010                1015                1020

 Asn Arg Pro Leu Leu Arg Asn Ser Leu Asp Asp Leu Val Gly Pro
                1025                1030                1035

 Pro Ser Asn Leu Glu Gly Gln Ser Asp Glu Arg Ala Leu Leu Asp
                1040                1045                1050

 Gln Leu His Thr Leu Leu Ser Asn Thr Asp Ala Thr Gly Leu Glu
                1055                1060                1065

 Glu Ile Asp Arg Ala Leu Gly Ile Pro Glu Leu Val Asn Gln Gly
                1070                1075                1080

 Gln Ala Leu Glu Pro Lys Gln Asp Ala Phe Gln Gly Gln Glu Ala
                1085                1090                1095

 Ala Val Met Met Asp Gln Lys Ala Gly Leu Tyr Gly Gln Thr Tyr
                1100                1105                1110

 Pro Ala Gln Gly Pro Pro Met Gln Gly Gly Phe His Leu Gln Gly
                1115                1120                1125

 Gln Ser Pro Ser Phe Asn Ser Met Met Asn Gln Met Asn Gln Gln
                1130                1135                1140

 Gly Asn Phe Pro Leu Gln Gly Met His Pro Arg Ala Asn Ile Met
                1145                1150                1155

 Arg Pro Arg Thr Asn Thr Pro Lys Gln Leu Arg Met Gln Leu Gln
                1160                1165                1170

 Gln Arg Leu Gln Gly Gln Gln Phe Leu Asn Gln Ser Arg Gln Ala
                1175                1180                1185

 Leu Glu Leu Lys Met Glu Asn Pro Thr Ala Gly Gly Ala Ala Val
                1190                1195                1200

 Met Arg Pro Met Met Gln Pro Gln Gln Gly Phe Leu Asn Ala Gln
                1205                1210                1215

 Met Val Ala Gln Arg Ser Arg Glu Leu Leu Ser His His Phe Arg
                1220                1225                1230

 Gln Gln Arg Val Ala Met Met Met Gln Gln Gln Gln Gln Gln Gln
                1235                1240                1245

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                1250                1255                1260

 Gln Gln Gln Gln Thr Gln Ala Phe Ser Pro Pro Pro Asn Val Thr
                1265                1270                1275

 Ala Ser Pro Ser Met Asp Gly Leu Leu Ala Gly Pro Thr Met Pro
                1280                1285                1290

 Gln Ala Pro Pro Gln Gln Phe Pro Tyr Gln Pro Asn Tyr Gly Met
                1295                1300                1305

 Gly Gln Gln Pro Asp Pro Ala Phe Gly Arg Val Ser Ser Pro Pro
                1310                1315                1320

 Asn Ala Met Met Ser Ser Arg Met Gly Pro Ser Gln Asn Pro Met
                1325                1330                1335

 Met Gln His Pro Gln Ala Ala Ser Ile Tyr Gln Ser Ser Glu Met
                1340                1345                1350

 Lys Gly Trp Pro Ser Gly Asn Leu Ala Arg Asn Ser Ser Phe Ser
                1355                1360                1365

 Gln Gln Gln Phe Ala His Gln Gly Asn Pro Ala Val Tyr Ser Met
                1370                1375                1380

 Val His Met Asn Gly Ser Ser Gly His Met Gly Gln Met Asn Met
                1385                1390                1395

 Asn Pro Met Pro Met Ser Gly Met Pro Met Gly Pro Asp Gln Lys
                1400                1405                1410

 Tyr Cys


<210> 1925
<211> 965
<212> DNA
<213> Homo sapien

<400> 1925
 cagcttgtcc tctatgactt acccagaagg caacgcttct ctttctggtc 50

 aaaatggctg gtaagcaggc cgtttcagca tcaggcaagt ggctggatgg 100

 tattcgaaaa tggtattaca atgctgcagg attcaataaa ctggggttaa 150

 tgcgagatga tacaatatac gaggatgaag atgtaaaaga agccataaga 200

 agacttcctg agaaccttta taatgacagg atgtttcgca ttaagagggc 250

 actggacctg aacttgaagc atcagatctt gcctaaagag cagtggacca 300

 aatatgaaga ggaaaatttc taccttgaac cgtatctgaa agaggttatt 350

 cgggaaagaa aagaaagaga agaatgggca aagaagtaat catgtagttg 400

 aagtctgtgg atgcagctgt tatgaagatg gttaaacttg aaacaaacaa 450

 ttttaagaat tatttggtct gaagatgttt tactttaaat aaatgtctat 500

 tgtaatggct ggagtttttg aattccaaac cttatactga ataactactg 550

 aatcccttta ctgttaaatt tttttccaaa ctttcaagat atatttagtt 600

 gtgtttaact gctacttgga gctcagaagc cactttatca gttttcctca 650

 ctggttggat agcctatcag tttatggaag gatataactt ccgtaagtta 700

 catccttatg gaagctactg aataaaagaa gggggtatgc accccctagt 750

 ttgccaagat tgagaaatag cctcttcact ggtatgcaaa cagatttgat 800

 tttgcatcct atcatttaaa aagaaattat gtctgcaccc caacataggc 850

 atacttaagt aatatacata ctcctgtgct aacatgtata ctagaaaaca 900

 aaaagatgtt agaaaaataa aagtataaag acaaatcaaa aaaaaaaaaa 950

 aaaaaaaaaa aaaaa 965

<210> 1926
<211> 111
<212> PRT
<213> Homo sapien

<400> 1926
 Met Ala Gly Lys Gln Ala Val Ser Ala Ser Gly Lys Trp Leu Asp
   1               5                  10                  15

 Gly Ile Arg Lys Trp Tyr Tyr Asn Ala Ala Gly Phe Asn Lys Leu
                  20                  25                  30

 Gly Leu Met Arg Asp Asp Thr Ile Tyr Glu Asp Glu Asp Val Lys
                  35                  40                  45

 Glu Ala Ile Arg Arg Leu Pro Glu Asn Leu Tyr Asn Asp Arg Met
                  50                  55                  60

 Phe Arg Ile Lys Arg Ala Leu Asp Leu Asn Leu Lys His Gln Ile
                  65                  70                  75

 Leu Pro Lys Glu Gln Trp Thr Lys Tyr Glu Glu Glu Asn Phe Tyr
                  80                  85                  90

 Leu Glu Pro Tyr Leu Lys Glu Val Ile Arg Glu Arg Lys Glu Arg
                  95                 100                 105

 Glu Glu Trp Ala Lys Lys
                 110

<210> 1927
<211> 3409
<212> DNA
<213> Homo sapien

<400> 1927
 gtcatctggc cagcccccgc ccctcctccc ggcgtcagcc cgccagaggc 50

 cgcgcggggc ccgggcttcg gccgatcagc ccgggaggcc ccgccgcgcc 100

 cccttggccc gcgcgcccgt ggtcacagtg gaagaggcgc ccgcgctgcg 150

 ctgcccggag gagccgtcgc gcgcccgctt cctgttcggc tggttcctgc 200

 cagctcgagg acaaaacacg cgtgcgcgcg gcgggcgagc gcgctcgccg 250

 cctcagtcgc cagcgccggg cgcagtccgc ctttttccgg agcagactgg 300

 ccgcggtgct agtcggtagc agcggccgcc gcagcggctc cgcactggcg 350

 aaccgagggc agaaaaaggc ggggttgacg gctttttggt aggagtgggc 400

 tggaccggac gccagagaca aaggctccca aggcaagagg gactgtggcc 450

 ctgcgtcggc tctgctcgga actgctgacc ccaggaattt acgccccttc 500

 gtttttctct tctgattctt ctcttctccc aagcccgcgt cccctcacgc 550

 gtggcctctc tccttgccgg gagggccgcg atggaggtcc cgcccaggct 600

 ttcccatgtg ccgccgccat tgttcccctc cgctcccgct actttagcct 650

 cccgcagcct ctcccattgg cggccgcggc cgccgcggca gctagccccg 700

 ctcctccctt cgctcgctcc cagctccgcc cggcaggggg cgcgccgggc 750

 ccagcgccac gtcaccgccc agcagccctc ccgattggcg ggcggggcgg 800

 ctataaaggg agggcgcagg cggcgcccgg atctcttccg ccgccatttt 850

 aaatccagct ccatacaacg ctccgccgcc gctgctgccg cgacccggac 900

 tgcgcgccag cacccccctg ccgacagctc cgtcactatg gaggatatga 950

 acgagtacag caatatagag gaattcgcag agggatccaa gatcaacgcg 1000

 agcaagaatc agcaggatga cggtaaaatg tttattggag gcttgagctg 1050

 ggatacaagc aaaaaagatc tgacagagta cttgtctcga tttggggaag 1100

 ttgtagactg cacaattaaa acagatccag tcactgggag atcaagagga 1150

 tttggatttg tgcttttcaa agatgctgct agtgttgata aggttttgga 1200

 actgaaagaa cacaaactgg atggcaaatt gatagatccc aaaagggcca 1250

 aagctttaaa agggaaagaa cctcccaaaa aggtttttgt gggtggattg 1300

 agcccggata cttctgaaga acaaattaaa gaatattttg gagcctttgg 1350

 agagattgaa aatattgaac ttcccatgga tacaaaaaca aatgaaagaa 1400

 gaggattttg ttttatcaca tatactgatg aagagccagt aaaaaaattg 1450

 ttagaaagca gataccatca aattggttct gggaagtgtg aaatcaaagt 1500

 tgcacaaccc aaagaggtat ataggcagca acagcaacaa caaaaaggtg 1550

 gaagaggtgc tgcagctggt ggacgaggtg gtacgagggg tcgtggccga 1600

 ggtcagggcc aaaactggaa ccaaggattt aataactatt atgatcaagg 1650

 atatggaaat tacaatagtg cctatggtgg tgatcaaaac tatagtggct 1700

 atggcggata tgattatact gggtataact atgggaacta tggatatgga 1750

 cagggatatg cagactacag tggccaacag agcacttatg gcaaggcatc 1800

 tcgagggggt ggcaatcacc aaaacaatta ccagccatac taaaggagaa 1850

 cattggagaa aacaggagga gatgttaaag taacccatct tgcaggacga 1900

 cattgaagat tggtcttctg ttgatctaag atgattattt tgtaaaagac 1950

 tttctagtgt acaagacacc attgtgtcca actgtatata gctgccaatt 2000

 agttttcttt gtttttactt tgtcctttgc tatctgtgtt atgactcaat 2050

 gtggatttgt ttatacacat tttatttgta tcatttcatg ttaaacctca 2100

 aataaatgct tccttatgtg attgcttttc tgcgtcaggt actacatagc 2150

 tctgtaaaaa atgtaattta aaataagcaa taattaaggc acagttgatt 2200

 ttgtagagta ttggtccata cagagaaact gtggtccttt ataaatagcc 2250

 agccagcgtc accctcttct ccaatttgta ggtgtatttt atgctcttaa 2300

 ggcttcatct tctccctgta actgagattt ctaccacacc tttgaacaat 2350

 gttctttccc ttctggttat ctgaagactg tcctgaaagg aagacataag 2400

 tgttgtgatt agtagaagct ttgtaatcat aacacaatga gtaattcttg 2450

 tataaaagtt cagatacaaa aggagcactg taaaactggt aggagctatg 2500

 gtttaagagc attggaagta gttacaactc aaggattttg gtagaaaggt 2550

 atgagtttgg tcgaaaaatt aaaatagtgg caaaataaga tttagttgtg 2600

 ttttctcaga gccgccacaa gattgaacaa aatgttttct gtttgggcat 2650

 cctgaggaag ttgtattagc tgttaatgct ctgtgagttt agagaaaagt 2700

 cttgatagta aatctagttt ttgacacagt gcatgaacta agtagttaaa 2750

 tatttacata ttcagaaagg aatagtggaa aaggtatctt ggttatgaca 2800

 aagtcattac aaatgtgact aagtcattac aaatgtgact gagtcattac 2850

 agtggaccct ctgggtgcat tgaaaagaat ccgttttata tccaggtttc 2900

 agaggacctg gaataataat aagctttgga ttttgcattc agtgtagttg 2950

 gattttggga ccttggcctc agtgttattt actgggattg gcatacgtgt 3000

 tcacaggcag agtagttgat ctcacacaac gggtgatctc acaaaactgg 3050

 taagtttctt atgctcatga gccctccctt ttttttttta atttggtgcc 3100

 tgcaactttc ttaacaatga ttctacttcc tgggctatca cattataatg 3150

 ctcttggcct cttttttgct gctgttttgc tattcttaaa cttaggccaa 3200

 gtaccaatgt tggctgttag aagggattct gttcattcaa catgcaactt 3250

 tagggaatgg aagtaagttc atttttaagt tgtgtggtca gtaggtgcgg 3300

 tgtctagggt agtgaatcct gtaagttcaa atttatgatt aggtgacgag 3350

 ttgacattga gattgtcctt ttcccctgat caaaaaaatg aataaagcct 3400

 ttttaaacg 3409

<210> 1928
<211> 420
<212> PRT
<213> Homo sapien

<400> 1928
 Met Glu Val Pro Pro Arg Leu Ser His Val Pro Pro Pro Leu Phe
   1               5                  10                  15

 Pro Ser Ala Pro Ala Thr Leu Ala Ser Arg Ser Leu Ser His Trp
                  20                  25                  30

 Arg Pro Arg Pro Pro Arg Gln Leu Ala Pro Leu Leu Pro Ser Leu
                  35                  40                  45

 Ala Pro Ser Ser Ala Arg Gln Gly Ala Arg Arg Ala Gln Arg His
                  50                  55                  60

 Val Thr Ala Gln Gln Pro Ser Arg Leu Ala Gly Gly Ala Ala Ile
                  65                  70                  75

 Lys Gly Gly Arg Arg Arg Arg Pro Asp Leu Phe Arg Arg His Phe
                  80                  85                  90

 Lys Ser Ser Ser Ile Gln Arg Ser Ala Ala Ala Ala Ala Ala Thr
                  95                 100                 105

 Arg Thr Ala Arg Gln His Pro Pro Ala Asp Ser Ser Val Thr Met
                 110                 115                 120

 Glu Asp Met Asn Glu Tyr Ser Asn Ile Glu Glu Phe Ala Glu Gly
                 125                 130                 135

 Ser Lys Ile Asn Ala Ser Lys Asn Gln Gln Asp Asp Gly Lys Met
                 140                 145                 150

 Phe Ile Gly Gly Leu Ser Trp Asp Thr Ser Lys Lys Asp Leu Thr
                 155                 160                 165

 Glu Tyr Leu Ser Arg Phe Gly Glu Val Val Asp Cys Thr Ile Lys
                 170                 175                 180

 Thr Asp Pro Val Thr Gly Arg Ser Arg Gly Phe Gly Phe Val Leu
                 185                 190                 195

 Phe Lys Asp Ala Ala Ser Val Asp Lys Val Leu Glu Leu Lys Glu
                 200                 205                 210

 His Lys Leu Asp Gly Lys Leu Ile Asp Pro Lys Arg Ala Lys Ala
                 215                 220                 225

 Leu Lys Gly Lys Glu Pro Pro Lys Lys Val Phe Val Gly Gly Leu
                 230                 235                 240

 Ser Pro Asp Thr Ser Glu Glu Gln Ile Lys Glu Tyr Phe Gly Ala
                 245                 250                 255

 Phe Gly Glu Ile Glu Asn Ile Glu Leu Pro Met Asp Thr Lys Thr
                 260                 265                 270

 Asn Glu Arg Arg Gly Phe Cys Phe Ile Thr Tyr Thr Asp Glu Glu
                 275                 280                 285

 Pro Val Lys Lys Leu Leu Glu Ser Arg Tyr His Gln Ile Gly Ser
                 290                 295                 300

 Gly Lys Cys Glu Ile Lys Val Ala Gln Pro Lys Glu Val Tyr Arg
                 305                 310                 315

 Gln Gln Gln Gln Gln Gln Lys Gly Gly Arg Gly Ala Ala Ala Gly
                 320                 325                 330

 Gly Arg Gly Gly Thr Arg Gly Arg Gly Arg Gly Gln Gly Gln Asn
                 335                 340                 345

 Trp Asn Gln Gly Phe Asn Asn Tyr Tyr Asp Gln Gly Tyr Gly Asn
                 350                 355                 360

 Tyr Asn Ser Ala Tyr Gly Gly Asp Gln Asn Tyr Ser Gly Tyr Gly
                 365                 370                 375

 Gly Tyr Asp Tyr Thr Gly Tyr Asn Tyr Gly Asn Tyr Gly Tyr Gly
                 380                 385                 390

 Gln Gly Tyr Ala Asp Tyr Ser Gly Gln Gln Ser Thr Tyr Gly Lys
                 395                 400                 405

 Ala Ser Arg Gly Gly Gly Asn His Gln Asn Asn Tyr Gln Pro Tyr
                 410                 415                 420

<210> 1929
<211> 5185
<212> DNA
<213> Homo sapien

<400> 1929
 gtccttgctt cttttttcat tgatgtaaat ttttttaact taatatgaaa 50

 actctccaag tcttgatcat cagccaggat tttgccacag caatttcatt 100

 ctcttatcgg agcttgtatg tgtcaaagta tacttcagag tgcaaacatt 150

 aagcaagtaa tatattttac ctacagatac ttatgaagac attctttcgc 200

 tatcgtgagt aaaagtatat aaagctgttt ctaactgaaa atgcttgaaa 250

 taagcctgta atagaaatat tttttcattt tttaaaaaag ggcggaattc 300

 ccagactgtc ttcgccttct tgcacttcgc gggagaagtt gttggcgcga 350

 atggatcctg agcctcgata acagattcct caaccggccc acccgccagc 400

 cagccagcgc cttcatcctg gggctgcgat ggacattcgg aaattctttg 450

 gagtaatacc aagtggaaag aaacttgtaa gtgaaacagt aaagaagaat 500

 gagaaaacaa agtctgatga agaaacttta aaagcaaaga aaggaataaa 550

 ggaaatcaag gtaaatagct cccgtaaaga ggatgacttc aaacaaaagc 600

 aaccaagcaa gaaaaagagg atcatctatg attcagattc agagtcagag 650

 gagacgttgc aggtaaaaaa tgccaaaaag ccaccagaaa aactgccagt 700

 atcttctaaa cctggtaaaa tttcacggca ggatcctgtt acatacattt 750

 cagaaacaga tgaagaagat gactttatgt gtaagaaggc ggcctctaaa 800

 tcaaaagaga atggaagatc tacaaatagt catcttggaa catcaaacat 850

 gaaaaagaat gaagaaaaca ctaagaccaa gaataagcct ttatcaccaa 900

 taaaacttac acccacatca gtacttgatt attttggaac tggaagtgtc 950

 caaagatcta ataagaagat ggtggcaagc aaaagaaaag agctttcaca 1000

 aaatacagat gagtctggat taaatgatga agccatcgcc aagcaattac 1050

 agcttgatga agatgcggag ctggagaggc agttgcatga agatgaagag 1100

 tttgccagaa cattagccat gttggatgaa gaacccaaga ccaaaaaggc 1150

 tcgaaaggac acagaagcgg gagaaacgtt ttcatctgtc caagccaatt 1200

 taagtaaagc agaaaaacat aaatatcctc ataaagtaaa aacagcacaa 1250

 gtttcagatg aaagaaagag ctacagtcct aggaagcaaa gtaaatatga 1300

 aagttcaaaa gaatctcagc aacattccaa gtcatcagct gacaaaatag 1350

 gagaagtctc ttctcccaag gccagttcta agctggcaat tatgaaaaga 1400

 aaagaagaga gctcttataa agaaatagag cctgtggcct caaaaagaaa 1450

 agaaaatgcc attaaattga aaggagagac aaaaactcct aagaaaacca 1500

 aaagttctcc agctaaaaaa gagtctgtaa gtcctgaaga ttctgaaaag 1550

 aaacgcacta attatcaagc ttatcgaagc tacttaaatc gagaaggtcc 1600

 caaggctctg ggctccaaag aaataccaaa gggagctgaa aattgcttgg 1650

 aaggccttat atttgtaatc acaggcgtgc tggagtctat tgaacgagat 1700

 gaggccaagt ctctaattga acgttatggg ggaaaagtaa caggaaatgt 1750

 cagcaagaaa acaaattatc ttgtcatggg tcgtgatagt ggacagtcca 1800

 agagtgataa ggccgcagcc ttggggacaa aaattattga tgaagatggc 1850

 ctgttgaatc tgattcggac tatgccaggc aagaaatcca agtatgaaat 1900

 agcagttgaa actgagatga agaaagagtc caaactggag agaacacccc 1950

 aaaaaaatgt ccaaggaaaa agaaaaatta gtccatctaa aaaggaatca 2000

 gaatctaaaa agagcaggcc gacttccaaa agggacagtt tggcaaagac 2050

 aataaaaaag gaaacagatg tgttttggaa aagcctggat ttcaaggagc 2100

 aggtggctga ggagacaagt ggtgacagca aggctaggaa tttggctgat 2150

 gacagcagtg aaaacaaagt ggaaaatttg ctctgggtgg ataaatataa 2200

 gccaacctcg ctcaagacca taattggaca gcaaggtgac cagagctgtg 2250

 ccaacaaact cctacgctgg ctccgaaact ggcaaaagag ttcttccgaa 2300

 gataaaaaac acgcagcaaa gtttggtaaa ttttccggca aagatgatgg 2350

 ctctagtttt aaagcagcgt tgctgtcagg ccctcctggt gttggcaaaa 2400

 ccaccacagc ttccctggtg tgtcaggagt tgggatacag ctacgtggaa 2450

 ctgaatgcaa gtgacacccg gagtaagagc agtttgaagg cgattgttgc 2500

 tgagtcactg aacaatacca gcatcaaagg cttttattca aatggagcag 2550

 cctcttcagt aagcacgaaa catgctctca tcatggatga agtagatggc 2600

 atggcaggca atgaggatag gggaggaatt caggaattaa ttggcctgat 2650

 aaaacatact aaaattccca ttatttgtat gtgcaatgat agaaatcatc 2700

 ccaagattcg ctctctggtt cattattgtt ttgatcttcg ttttcaaaga 2750

 cctcgggttg aacagattaa gggtgctatg atgtctattg catttaaaga 2800

 aggtttaaag attccccctc cagctatgaa tgaaataatt ttgggagcca 2850

 atcaagatat cagacaggtt ttacataatc tgagtatgtg gtgtgcacga 2900

 agtaaagcat taacctatga ccaggccaaa gctgattctc acagagccaa 2950

 aaaggatatc aaaatgggcc catttgatgt tgcccggaaa gtgtttgcag 3000

 ctggagagga gactgctcac atgtcacttg tggacaagtc agatctcttt 3050

 tttcatgatt attcaatagc acccctcttc gtccaggaaa attacataca 3100

 cgtgaagcct gtagcagcag ggggtgacat gaaaaagcac ctgatgcttt 3150

 taagcagagc agcagacagc atatgcgatg gtgacctagt ggacagccag 3200

 atccggagta agcaaaactg gagtcttctg cctgcgcagg ccatttatgc 3250

 cagtgttctt cctggagagt tgatgagggg gtacatgacc cagtttccca 3300

 ccttcccaag ctggctgggg aagcactcgt ctacaggcaa acatgatcgt 3350

 attgttcagg acctggcctt gcatatgagt ctcagaactt actccagcaa 3400

 aaggactgta aacatggatt atctgtcgct tctaagggat gcacttgtac 3450

 agcccttgac ctcacaagga gtagacggag tacaggatgt tgttgcactt 3500

 atggacacat attatttgat gaaagaagac tttgagaata tcatggaaat 3550

 cagcagctgg ggtggcaaac ctagtccctt ttcaaagctg gatcccaagg 3600

 tgaaagcagc cttcacaaga gcttacaata aggaagccca ccttactcca 3650

 tactcacttc aagctataaa ggcatctaga cacagcacaa gcccatccct 3700

 ggattcggaa tacaatgaag aattaaatga agatgactct caatctgatg 3750

 agaaagacca agatgctata gaaactgatg ccatgatcaa gaaaaagaca 3800

 aaatcttcaa agccttcaaa accagaaaaa gataaggagc ccagaaaagg 3850

 aaaaggaaaa agttcgaaga aatgaaacca tttttcacta gcgacagcca 3900

 ctttttactc tccctcctga ccagtccagc tggtctagag aaagccttgt 3950

 tttttcccag agcaaccatg ttttagcata atgggatgac ctggtgtccc 4000

 attataaata aagggtggta tggctagaag ggtatgagca gtaggcttat 4050

 gtacacctct tatagaggtt gataggactg cttgggtcct ccactgtcct 4100

 ctgtcaatct agttagacgt gcttctgaat gactgtagaa ttggaactag 4150

 aaactacacc tgggctttgg agtcagattt tagttaacaa taatgagcct 4200

 ggagcagtag tactaaggcg tcttttgtag gcttaagaat ttatcctaat 4250

 ggcctttata ggaccaatgc tgattttttt taaaggcagt tcctattatg 4300

 tggtgaaatt ttgtaaataa atgattatac aaaacagtca ccacctagaa 4350

 ctgggtattc tttgtacatt gtcagatatc tttcaaagta taaattagga 4400

 ataaaaatgt tccacatgat atgtgtacaa attcttttta agattgtcat 4450

 cttgtacagc aaaatattat gttggtatat tacttcctta ttaatttgca 4500

 aatgattgga ttaaaaaagc tcactgtatt ccttactaac ctgttgtgtg 4550

 aaacataaca ttggcagtcg aggagtcaga actcggattc ccagcctcac 4600

 tccctctgtg tgtgttgacc acgtctctgc tgtgaatagg atttcatgca 4650

 gtggtctgtt atggggcttt gcagcgtggg gggctgcaga agattctcag 4700

 acattcttat ccttctggag tctcaaccca tcaggttcag accagtagga 4750

 accaggctgg gtcaggctct taatttcact acggtggggg acaaaatgaa 4800

 cactggcttt tgttcacttt gcccctgaga gatctagtcc tgtcctgtga 4850

 tggcttccac aaaccctgtt ggaagtttgg gttattccta taactgtatg 4900

 tgttgagtgg ccgtgacgta tggacctagc ctggaattta gatgtctagc 4950

 tattttttaa tcttgttggt aaatgctcag aggtctgtgc tacctctgtg 5000

 aggtatatac taaaatgaat gtaaaataag gatcgtattc cctgctttaa 5050

 ggaactggta gtcttgtttg ggtgatgaga caaagttctt gagacattta 5100

 aactgtattt accagtgtga aaaatgtcat ttatggagat taattcatta 5150

 tggaaataaa acattgccta agcccttgcc tgctg 5185

<210> 1930
<211> 1148
<212> PRT
<213> Homo sapien

<400> 1930
 Met Asp Ile Arg Lys Phe Phe Gly Val Ile Pro Ser Gly Lys Lys
   1               5                  10                  15

 Leu Val Ser Glu Thr Val Lys Lys Asn Glu Lys Thr Lys Ser Asp
                  20                  25                  30

 Glu Glu Thr Leu Lys Ala Lys Lys Gly Ile Lys Glu Ile Lys Val
                  35                  40                  45

 Asn Ser Ser Arg Lys Glu Asp Asp Phe Lys Gln Lys Gln Pro Ser
                  50                  55                  60

 Lys Lys Lys Arg Ile Ile Tyr Asp Ser Asp Ser Glu Ser Glu Glu
                  65                  70                  75

 Thr Leu Gln Val Lys Asn Ala Lys Lys Pro Pro Glu Lys Leu Pro
                  80                  85                  90

 Val Ser Ser Lys Pro Gly Lys Ile Ser Arg Gln Asp Pro Val Thr
                  95                 100                 105

 Tyr Ile Ser Glu Thr Asp Glu Glu Asp Asp Phe Met Cys Lys Lys
                 110                 115                 120

 Ala Ala Ser Lys Ser Lys Glu Asn Gly Arg Ser Thr Asn Ser His
                 125                 130                 135

 Leu Gly Thr Ser Asn Met Lys Lys Asn Glu Glu Asn Thr Lys Thr
                 140                 145                 150

 Lys Asn Lys Pro Leu Ser Pro Ile Lys Leu Thr Pro Thr Ser Val
                 155                 160                 165

 Leu Asp Tyr Phe Gly Thr Gly Ser Val Gln Arg Ser Asn Lys Lys
                 170                 175                 180

 Met Val Ala Ser Lys Arg Lys Glu Leu Ser Gln Asn Thr Asp Glu
                 185                 190                 195

 Ser Gly Leu Asn Asp Glu Ala Ile Ala Lys Gln Leu Gln Leu Asp
                 200                 205                 210

 Glu Asp Ala Glu Leu Glu Arg Gln Leu His Glu Asp Glu Glu Phe
                 215                 220                 225

 Ala Arg Thr Leu Ala Met Leu Asp Glu Glu Pro Lys Thr Lys Lys
                 230                 235                 240

 Ala Arg Lys Asp Thr Glu Ala Gly Glu Thr Phe Ser Ser Val Gln
                 245                 250                 255

 Ala Asn Leu Ser Lys Ala Glu Lys His Lys Tyr Pro His Lys Val
                 260                 265                 270

 Lys Thr Ala Gln Val Ser Asp Glu Arg Lys Ser Tyr Ser Pro Arg
                 275                 280                 285

 Lys Gln Ser Lys Tyr Glu Ser Ser Lys Glu Ser Gln Gln His Ser
                 290                 295                 300

 Lys Ser Ser Ala Asp Lys Ile Gly Glu Val Ser Ser Pro Lys Ala
                 305                 310                 315

 Ser Ser Lys Leu Ala Ile Met Lys Arg Lys Glu Glu Ser Ser Tyr
                 320                 325                 330

 Lys Glu Ile Glu Pro Val Ala Ser Lys Arg Lys Glu Asn Ala Ile
                 335                 340                 345

 Lys Leu Lys Gly Glu Thr Lys Thr Pro Lys Lys Thr Lys Ser Ser
                 350                 355                 360

 Pro Ala Lys Lys Glu Ser Val Ser Pro Glu Asp Ser Glu Lys Lys
                 365                 370                 375

 Arg Thr Asn Tyr Gln Ala Tyr Arg Ser Tyr Leu Asn Arg Glu Gly
                 380                 385                 390

 Pro Lys Ala Leu Gly Ser Lys Glu Ile Pro Lys Gly Ala Glu Asn
                 395                 400                 405

 Cys Leu Glu Gly Leu Ile Phe Val Ile Thr Gly Val Leu Glu Ser
                 410                 415                 420

 Ile Glu Arg Asp Glu Ala Lys Ser Leu Ile Glu Arg Tyr Gly Gly
                 425                 430                 435

 Lys Val Thr Gly Asn Val Ser Lys Lys Thr Asn Tyr Leu Val Met
                 440                 445                 450

 Gly Arg Asp Ser Gly Gln Ser Lys Ser Asp Lys Ala Ala Ala Leu
                 455                 460                 465

 Gly Thr Lys Ile Ile Asp Glu Asp Gly Leu Leu Asn Leu Ile Arg
                 470                 475                 480

 Thr Met Pro Gly Lys Lys Ser Lys Tyr Glu Ile Ala Val Glu Thr
                 485                 490                 495

 Glu Met Lys Lys Glu Ser Lys Leu Glu Arg Thr Pro Gln Lys Asn
                 500                 505                 510

 Val Gln Gly Lys Arg Lys Ile Ser Pro Ser Lys Lys Glu Ser Glu
                 515                 520                 525

 Ser Lys Lys Ser Arg Pro Thr Ser Lys Arg Asp Ser Leu Ala Lys
                 530                 535                 540

 Thr Ile Lys Lys Glu Thr Asp Val Phe Trp Lys Ser Leu Asp Phe
                 545                 550                 555

 Lys Glu Gln Val Ala Glu Glu Thr Ser Gly Asp Ser Lys Ala Arg
                 560                 565                 570

 Asn Leu Ala Asp Asp Ser Ser Glu Asn Lys Val Glu Asn Leu Leu
                 575                 580                 585

 Trp Val Asp Lys Tyr Lys Pro Thr Ser Leu Lys Thr Ile Ile Gly
                 590                 595                 600

 Gln Gln Gly Asp Gln Ser Cys Ala Asn Lys Leu Leu Arg Trp Leu
                 605                 610                 615

 Arg Asn Trp Gln Lys Ser Ser Ser Glu Asp Lys Lys His Ala Ala
                 620                 625                 630

 Lys Phe Gly Lys Phe Ser Gly Lys Asp Asp Gly Ser Ser Phe Lys
                 635                 640                 645

 Ala Ala Leu Leu Ser Gly Pro Pro Gly Val Gly Lys Thr Thr Thr
                 650                 655                 660

 Ala Ser Leu Val Cys Gln Glu Leu Gly Tyr Ser Tyr Val Glu Leu
                 665                 670                 675

 Asn Ala Ser Asp Thr Arg Ser Lys Ser Ser Leu Lys Ala Ile Val
                 680                 685                 690

 Ala Glu Ser Leu Asn Asn Thr Ser Ile Lys Gly Phe Tyr Ser Asn
                 695                 700                 705

 Gly Ala Ala Ser Ser Val Ser Thr Lys His Ala Leu Ile Met Asp
                 710                 715                 720

 Glu Val Asp Gly Met Ala Gly Asn Glu Asp Arg Gly Gly Ile Gln
                 725                 730                 735

 Glu Leu Ile Gly Leu Ile Lys His Thr Lys Ile Pro Ile Ile Cys
                 740                 745                 750

 Met Cys Asn Asp Arg Asn His Pro Lys Ile Arg Ser Leu Val His
                 755                 760                 765

 Tyr Cys Phe Asp Leu Arg Phe Gln Arg Pro Arg Val Glu Gln Ile
                 770                 775                 780

 Lys Gly Ala Met Met Ser Ile Ala Phe Lys Glu Gly Leu Lys Ile
                 785                 790                 795

 Pro Pro Pro Ala Met Asn Glu Ile Ile Leu Gly Ala Asn Gln Asp
                 800                 805                 810

 Ile Arg Gln Val Leu His Asn Leu Ser Met Trp Cys Ala Arg Ser
                 815                 820                 825

 Lys Ala Leu Thr Tyr Asp Gln Ala Lys Ala Asp Ser His Arg Ala
                 830                 835                 840

 Lys Lys Asp Ile Lys Met Gly Pro Phe Asp Val Ala Arg Lys Val
                 845                 850                 855

 Phe Ala Ala Gly Glu Glu Thr Ala His Met Ser Leu Val Asp Lys
                 860                 865                 870

 Ser Asp Leu Phe Phe His Asp Tyr Ser Ile Ala Pro Leu Phe Val
                 875                 880                 885

 Gln Glu Asn Tyr Ile His Val Lys Pro Val Ala Ala Gly Gly Asp
                 890                 895                 900

 Met Lys Lys His Leu Met Leu Leu Ser Arg Ala Ala Asp Ser Ile
                 905                 910                 915

 Cys Asp Gly Asp Leu Val Asp Ser Gln Ile Arg Ser Lys Gln Asn
                 920                 925                 930

 Trp Ser Leu Leu Pro Ala Gln Ala Ile Tyr Ala Ser Val Leu Pro
                 935                 940                 945

 Gly Glu Leu Met Arg Gly Tyr Met Thr Gln Phe Pro Thr Phe Pro
                 950                 955                 960

 Ser Trp Leu Gly Lys His Ser Ser Thr Gly Lys His Asp Arg Ile
                 965                 970                 975

 Val Gln Asp Leu Ala Leu His Met Ser Leu Arg Thr Tyr Ser Ser
                 980                 985                 990

 Lys Arg Thr Val Asn Met Asp Tyr Leu Ser Leu Leu Arg Asp Ala
                 995                1000                1005

 Leu Val Gln Pro Leu Thr Ser Gln Gly Val Asp Gly Val Gln Asp
                1010                1015                1020

 Val Val Ala Leu Met Asp Thr Tyr Tyr Leu Met Lys Glu Asp Phe
                1025                1030                1035

 Glu Asn Ile Met Glu Ile Ser Ser Trp Gly Gly Lys Pro Ser Pro
                1040                1045                1050

 Phe Ser Lys Leu Asp Pro Lys Val Lys Ala Ala Phe Thr Arg Ala
                1055                1060                1065

 Tyr Asn Lys Glu Ala His Leu Thr Pro Tyr Ser Leu Gln Ala Ile
                1070                1075                1080

 Lys Ala Ser Arg His Ser Thr Ser Pro Ser Leu Asp Ser Glu Tyr
                1085                1090                1095

 Asn Glu Glu Leu Asn Glu Asp Asp Ser Gln Ser Asp Glu Lys Asp
                1100                1105                1110

 Gln Asp Ala Ile Glu Thr Asp Ala Met Ile Lys Lys Lys Thr Lys
                1115                1120                1125

 Ser Ser Lys Pro Ser Lys Pro Glu Lys Asp Lys Glu Pro Arg Lys
                1130                1135                1140

 Gly Lys Gly Lys Ser Ser Lys Lys
                1145

<210> 1931
<211> 5717
<212> DNA
<213> Homo sapien

<400> 1931
 attaagcttt agcgtaacag attcttttca atcaagtact ggaatcagtt 50

 gtccaggtgg agtaatacag aaaagctaag gtctagaaac caggggacca 100

 ttttagatac aaagcagaat tgcggaattg ccagattata acttgaggtt 150

 tgttcggggg atttttttta accatctaaa ataaatgtat ataagatgga 200

 ctgagtcttc taaagagatt ctaaaactat attcttactt aagtctgaac 250

 aggaattaag aataactcaa agtgaatttg atcgtcaagc agagattacc 300

 agacttctgc tagagggaat cagcagtaca catgcccatc accttcgctg 350

 tctgaatgac tttgtagaag cccagatgac ttactatgca cagtgttacc 400

 agtatatgtt ggacctccag aaacaactgg gaagttttcc atccaattat 450

 cttagtaaca acaatcagac ttctgtgaca cctgtaccat cagttttacc 500

 aaatgcgatt ggttcttctg ccatggcttc aacaagtggc ctagtaatca 550

 cctctccttc caacctcagt gaccttaagg agtgtagtgg cagcagaaag 600

 gccagggttc tctatgatta tgatgcagca aacagtactg aattatcact 650

 tctggcagat gaggtgatca ctgtgttcag tgttgttgga atggattcag 700

 actggctaat gggggaaagg ggaaaccaga agggcaaggt gccaattacc 750

 tacttagaac tgctcaatta agtaggtgga ctatggaaag gttgcccatc 800

 atgactttgt atttatatac aattaactct aaataaagca ggttaagtat 850

 cttccatgtt aatgtgttaa gagactgaaa ataccagcca tcagaaactg 900

 gcctttctgc caataaagtt gcatggtaaa tatttcatta cagaatttat 950

 gttagagctt tcatgccaag aatgttttct tacaaaattc tctttttatt 1000

 gaggtttcac taataagcag cttctacttt tgagcctcaa cttaaagcag 1050

 aactgttttc tactggattt ttcattaaca gcaagctttt tcttttatgt 1100

 aaaataaatc tattgtgaat tgatatcagc gactcattta ttaggtataa 1150

 ataatagcca aagaataaaa ttaaaattta ttttaaactt tcggtcttaa 1200

 aaagagctgt aggatataaa cctcttttgt gaaaagtaga attttctgaa 1250

 tgctttcata gacaaaaacg catttaaact atgtttacct ggttttccaa 1300

 cagaaatcaa atgattttaa tattatgttt tgatgggtta ttttcagagt 1350

 tgtttggttt tttaaacact actgaatggt ttcttttaaa tttaagaaca 1400

 actagttctt gaaaagcaat accgtatttc tctgataaat ttgtagttaa 1450

 ggttctagaa aatctaggac aaatttactt cattaaacat aaagttttta 1500

 agattattca gttggcacaa tttaatgcat aattgggatt ggatccattt 1550

 actgtactgt ggtacagtaa agagaatgtg ttcttattga acagcagatt 1600

 tgtatacaaa tacggaataa tgcaactaca ttataaattg tatacgaaca 1650

 aaataaattg ggtcactctg agcttactat taaaacattg aaaatttatt 1700

 aatgaacaca ggctatcttg atgaggatct ctgcttatga aacacatact 1750

 aatgaaatta ttagtgacac attggaagct agaaaattgc tgttggggcc 1800

 attgctataa atcattgttt ccatgttaag acttctgttc taattcattc 1850

 attcaacaaa catttgttga gggccagata ctgtgctggt caactgggga 1900

 tactgtcctg aacaatatgc acacagttct tgcccctgca gagcttaaag 1950

 accattaaag gatacagaaa attaagcaat tatcctatag taggattcgt 2000

 ggtgtgatgg ggaaaataca aggtactgta tttgggagtc atgtaactcc 2050

 agttttggga gtgagagagg gtctggggaa gaactgttcc agataaaaag 2100

 atgtgtaacc aagatagcat agcacattct gacaactaaa gcaatttact 2150

 ctaacttaag catgaagtac aaaagtatag ttcatttatt gagggaatgt 2200

 taagctatta aaatgatact ttttggtact tttaaaaaaa tgaatactta 2250

 aacaccgttt taaaattttg tgttaagagc tcctaataag aacttggtaa 2300

 acatgttgac aatttaactc acagtctaaa ctttaaaagt agtagttacc 2350

 cttttatttc tgtgccatga gacaaattct tctgcagttt tatagttgta 2400

 caagatgttt tgactcactc tcaattgcca tattcttaaa gaaaccctga 2450

 aaagctgctc aagctggtca gttttctgta aaaccaagta aatgaaattt 2500

 tctctcccct cagaaaggaa gttctacagc ctagagtacc atctattgtg 2550

 ttttataagt ccagatttag gctttgaaag atcataccaa aacttcagat 2600

 cgacttaaac agcaactatg aattaggttt atgggaaatg tagtaataca 2650

 ggggaaagaa tatcggtaat ggagtgaaat ggtcctgggt tcaaatccag 2700

 tcttcctcac atattgtgct ctttaagctt caaatgagat gtataactgc 2750

 cttttcctta ccagtaaaat gaggacaata attatgacac catagggtgg 2800

 ttgtgaggat tagcaaatgt tatcttgtat ttcaggtgcc tttcagggaa 2850

 aggcttggca catagtaaac acatcctgta aatatcagtt tccccttgtt 2900

 agcccctgta gcatcctgac ctaccaagtc tataggcctt gcatatcact 2950

 gtgcaccaga gatacctctt ttacatctgg gctctgtttt ctctctatca 3000

 atcctatcct ccaccctctt taaatcagac cccaggttta accttcccac 3050

 agtcagtata aatcattttt cagaactttc agctttccat caagtgaaag 3100

 ttgattttag ttacccagta atgtacagaa accttcaata atgttaagct 3150

 tcaaaggctt ctggtacgtt tgtctaccac agaaccacca caatatatat 3200

 gcttgttctt aggtttattg ctttttattt taatggggtt tggttgtttg 3250

 ggttttattt tggttttggc ttattttaaa gtcaagttta gtttttactc 3300

 aggtaaaggc ctgaagtttc ttgggcgtgg aagaaaaagc ttgggaagcc 3350

 tattaattca tggtgcagtt cagaattgtt taaataagct ctgtgccact 3400

 gagcttaatc tgaaagtata gtgacatgtg aaggatgcac atatgaatga 3450

 aaaactaaaa taattgtagg ctcttctata aatgaaaaaa aaagtgattg 3500

 gattgtgtct acctttttcc tcaaagtaat ctaacctaaa cggtcatggt 3550

 gttaaaactt tttatggtgc taatcagaaa aattgatgtt gcaagaaatg 3600

 aggtctcaaa aatgggaatg tgcctcctca ctctgcgtca catgggaaat 3650

 aaatcctgag gccaggatca ccagtggggt agagtcatct tcatagtctc 3700

 ctgttatcct ccccctgaac aaagaacaaa gtgagactgg gaagctagtg 3750

 ttggggaaac atttctggga taaactgtgg agtggagaag acaatggagg 3800

 gcaaggcaaa aacccacaga cttgtttacc catagaggcc ccactcacct 3850

 ccatgctgac agaattccag aaaaattcct tccctatctc ccaaacacct 3900

 gaaattctga aatattgccc tactatttag cactttaagc ttcagtgagg 3950

 tgctgtaatg gagagatagc ttcatagttt agcctatagc caactttgcc 4000

 tcaagacctc cagataagat gaagtggctt ttacctcatg tgagtctcaa 4050

 acgctggaga gagagttcca caaccacccc tgccctttct cccatattac 4100

 gctcattaga aagtctactc agggctgggt gccgtggctc atgcctgtaa 4150

 tcccagcact ttggaggctg aggcgggtgg atcatctgag gtcaggagtt 4200

 cgagaccagc ctggccaaca tggggaaacc ctgtctctac tgaaaatata 4250

 aaaattagcc gggcatggtg gcgtgcacct gtaattccag ctactcggga 4300

 ggctgaggca ggagaatcac ttgaacccca gaggcagagg ctacagtgag 4350

 ccaagattgc accactgcac tccaacctgg gtgatagaat aagactcttg 4400

 tctcaaggaa agaaaaaatg tctactcagt agagcagtga ttggcaaagt 4450

 gtgagacccc agaccggcaa tattggcatc tcctggagac ttgtttaaaa 4500

 tgctgattac tattttcaag aactttctac cttcattttt acttattttt 4550

 ttgttttcaa gggctcatgg aatcagtctt ccatgtgaca gctttttaaa 4600

 tattttaaga caaaaactga gtcttctaat cttaattgtg ttctagcagt 4650

 agtcattgta attatagtta tttttataat ttatttgttt agtgtatatc 4700

 tgtcactcta gaatgtaggc tccctgagat aaaaactata attcttttga 4750

 tggcagttac attcccaact cttagcacaa gatctaggac atagtatgaa 4800

 ctcaataaat ttttgttgaa tgaaagaaaa atgcaaattt ataagccttt 4850

 tcagagacct actgaatcaa actctgagag tggagcccag caatctgttg 4900

 taaaagctgt ttgagtaata ctgttgcact ctaagcttga gaaccactgc 4950

 aatagaacta agagaacatt catttcacct tcaggcctat tctctgacat 5000

 cacttgaaaa atcctctctg ccttctgtaa cccttaacca acaacagtgc 5050

 cctgtccatg taggggaaac ttctgggctg tattacaagt gggtaggaag 5100

 gtataaggat atcatagtgg gaagtattgc ttagaatgcc agtacttgtt 5150

 tgctgtggaa ggtttctagg aatggattgc ttagtctaaa gtaagcacta 5200

 ccaccatcca cgttttcact caacacagtg ccttttaatt ggtgactaac 5250

 atcaaaacac cttgacaaac cgttaaaaca gtatcagaaa ccatgtgtac 5300

 atccctgtgc ctcttagatt gctaagttct gctctcattc ttacttcaaa 5350

 ggacactttt taaagaattg ttaatgcttt tttataatac aagtcatagc 5400

 cctgttggca aaaagaaaaa agattcagtg agaaagaaaa atcactgata 5450

 attccatcat ccagggagaa ccactgttat ttaagtatat ggccttccag 5500

 acctttctgt gcatttatag atatttttaa tgggatcaaa gtgtacatac 5550

 tgttttgtaa ctttttttca ctcaacaata ccatgactgt cttgctgtgt 5600

 caagtatatt tctacatctc ttaatggctg catgatattc catcatatgt 5650

 gccacatttt attaaactac tgttcaattt ttaggtttcc aactttcatt 5700

 aataaagtgc tttaaag 5717

<210> 1932
<211> 2314
<212> DNA
<213> Homo sapien

<400> 1932
 atgggcccca aaaaatcttg gcgaagtcac ttttttccac tgcctgaggt 50

 ttggctgttg ctcctgttat cccaagctct aagcccttcc catggtcccc 100

 agacccaggc aggggtaggt ctcgtctgga gtgtcccgct gccaagtgcc 150

 ctgagaagcc agtcctgcct tggtgctcca ctgagggacg cttcggagtt 200

 aaccaccgtg cacttgttcc cgacgcgggg ctggggcgcg cgcagggcat 250

 tgtgggtgca tagttcagcc agcgcgtcgt cggctgctag ccgccgtcgc 300

 ctgcgcgctc aggcctctgg gattagtagt tttagcctcg tggatggcgg 350

 ggcgcctcgc gaagatggtg gcgcgcgtgg cgtgtggctc ccgtcgtctg 400

 gccaagtctc agcgcagcgc accggccggc gtctcgttgg cctggagccc 450

 acacccaccg ggtccctgac cccgcgcccc ccgcgcccgg ttcccggcat 500

 gcctcgcgcc cgtaagggca acacgctccg gaagggtggt cagcgccgtg 550

 gaggaggtgc ccggagcagt gcccaagctg actcgggttc cagtgacgat 600

 gaggcagcca gtgaggcccg cagcaccgcc agtgaatgcc ccagccttct 650

 cagcaccact gcagaggaca gccttggggg ggatgtcgtg gatgagcagg 700

 gccagcagga agaccttgag gaaaagctga aggagtatgt ggactgtctc 750

 acagacaaga gtgccaagac ccggcagggt gctcttgaga gcctgcgcct 800

 ggccctagcg tcccgcctac tccccgactt cttgctggag cgccgcctca 850

 cgctagccga tgccctggaa aagtgcctca agaaagggaa gggcgaggaa 900

 caagccctgg ctgctgctgt gctaggcctg ctctgcgtgc agctgggccc 950

 tggacctaag ggtgaggagc tgtttcacag cctgcagcct ctgctggtct 1000

 ctgtgctcag tgacagcaca gctagccctg ctgcccggct ccactgtgct 1050

 tctgcccttg gcctgggctg ctacgtggct gccgctgaca tccaggacct 1100

 ggtctcttgc cttgcctgct tagaaagtgt tttcagccgg ttctatggct 1150

 tggggggcag ctccacaagt cctgtggttc ctgccagcct gcacggcctg 1200

 ctctctgctg ccctgcaggc ctgggcattg ctgctcacca tctgccctag 1250

 cacccaaatc agccacatcc ttgacaggca gctgccccgg ctgccccagc 1300

 tcttgtccag tgaaagtgtg aacctgcgga tcgctgccgg tgaaaccatt 1350

 gcactgctct ttgagcttgc ccgggacctt gaggaggagt ttgtttacga 1400

 ggacatggag gccctctgca gtgtcctgcg cactctggcc actgacagta 1450

 acaagtaccg tgccaaggct gatcgtcggc gccagcgctc tactttccgc 1500

 gccgtgctgc actccgtgga gggcggtgaa tgcgaagaag agatagtgcg 1550

 cttcggcttt gaggtgctct acatggacag ctgggctcgg caccggatct 1600

 acgctgcctt caaggaagtg ctgggttcgg gcatgcacca ccacctccag 1650

 aacaatgagc tactccgtga catctttggc ctgggccctg tgctgttgct 1700

 ggatgccact gccctgaagg cctgcaaggt tccacgcttt gagaagcacc 1750

 tgtacaatgc tgctgccttc aaagcccgga ccaaggctcg aagccgtgtg 1800

 cgggacaagc gggcagacat cctgtgaagc aggacctgct gaagaggaga 1850

 ctttctatgc ccttggtccg tatttttaac agaagacagt gcaacaactg 1900

 gtctccacca gtatttgtca ctttattttt tttaatgaca aaaccaaaaa 1950

 cagacatggg gtgggtagct gggggcccgg acacttggga ccctgacccc 2000

 tttgtccctg cactcagccc tgtggcccct tcctgtcctg tctcaggcca 2050

 ggctaaatat gtgccttcct cagggctgtg gggcaggcac tagggggcct 2100

 ttcccttcct ttcctttctc aggccttgct cccccaggat gacccactct 2150

 taggggggtg gtggcatctg gacaaatgcc accacagcag gtggggtggc 2200

 aaagctacct ggaatggatt tgtgtgctga tttttaagga ttattacaga 2250

 taattaaaca gaacggtcag ccttcaaaaa aaaaaaaaaa aaaaaattcc 2300

 tgcggccgca aggc 2314

<210> 1933
<211> 608
<212> PRT
<213> Homo sapien

<400> 1933
 Met Gly Pro Lys Lys Ser Trp Arg Ser His Phe Phe Pro Leu Pro
   1               5                  10                  15

 Glu Val Trp Leu Leu Leu Leu Leu Ser Gln Ala Leu Ser Pro Ser
                  20                  25                  30

 His Gly Pro Gln Thr Gln Ala Gly Val Gly Leu Val Trp Ser Val
                  35                  40                  45

 Pro Leu Pro Ser Ala Leu Arg Ser Gln Ser Cys Leu Gly Ala Pro
                  50                  55                  60

 Leu Arg Asp Ala Ser Glu Leu Thr Thr Val His Leu Phe Pro Thr
                  65                  70                  75

 Arg Gly Trp Gly Ala Arg Arg Ala Leu Trp Val His Ser Ser Ala
                  80                  85                  90

 Ser Ala Ser Ser Ala Ala Ser Arg Arg Arg Leu Arg Ala Gln Ala
                  95                 100                 105

 Ser Gly Ile Ser Ser Phe Ser Leu Val Asp Gly Gly Ala Pro Arg
                 110                 115                 120

 Glu Asp Gly Gly Ala Arg Gly Val Trp Leu Pro Ser Ser Gly Gln
                 125                 130                 135

 Val Ser Ala Gln Arg Thr Gly Arg Arg Leu Val Gly Leu Glu Pro
                 140                 145                 150

 Thr Pro Thr Gly Ser Leu Thr Pro Arg Pro Pro Arg Pro Val Pro
                 155                 160                 165

 Gly Met Pro Arg Ala Arg Lys Gly Asn Thr Leu Arg Lys Gly Gly
                 170                 175                 180

 Gln Arg Arg Gly Gly Gly Ala Arg Ser Ser Ala Gln Ala Asp Ser
                 185                 190                 195

 Gly Ser Ser Asp Asp Glu Ala Ala Ser Glu Ala Arg Ser Thr Ala
                 200                 205                 210

 Ser Glu Cys Pro Ser Leu Leu Ser Thr Thr Ala Glu Asp Ser Leu
                 215                 220                 225

 Gly Gly Asp Val Val Asp Glu Gln Gly Gln Gln Glu Asp Leu Glu
                 230                 235                 240

 Glu Lys Leu Lys Glu Tyr Val Asp Cys Leu Thr Asp Lys Ser Ala
                 245                 250                 255

 Lys Thr Arg Gln Gly Ala Leu Glu Ser Leu Arg Leu Ala Leu Ala
                 260                 265                 270

 Ser Arg Leu Leu Pro Asp Phe Leu Leu Glu Arg Arg Leu Thr Leu
                 275                 280                 285

 Ala Asp Ala Leu Glu Lys Cys Leu Lys Lys Gly Lys Gly Glu Glu
                 290                 295                 300

 Gln Ala Leu Ala Ala Ala Val Leu Gly Leu Leu Cys Val Gln Leu
                 305                 310                 315

 Gly Pro Gly Pro Lys Gly Glu Glu Leu Phe His Ser Leu Gln Pro
                 320                 325                 330

 Leu Leu Val Ser Val Leu Ser Asp Ser Thr Ala Ser Pro Ala Ala
                 335                 340                 345

 Arg Leu His Cys Ala Ser Ala Leu Gly Leu Gly Cys Tyr Val Ala
                 350                 355                 360

 Ala Ala Asp Ile Gln Asp Leu Val Ser Cys Leu Ala Cys Leu Glu
                 365                 370                 375

 Ser Val Phe Ser Arg Phe Tyr Gly Leu Gly Gly Ser Ser Thr Ser
                 380                 385                 390

 Pro Val Val Pro Ala Ser Leu His Gly Leu Leu Ser Ala Ala Leu
                 395                 400                 405

 Gln Ala Trp Ala Leu Leu Leu Thr Ile Cys Pro Ser Thr Gln Ile
                 410                 415                 420

 Ser His Ile Leu Asp Arg Gln Leu Pro Arg Leu Pro Gln Leu Leu
                 425                 430                 435

 Ser Ser Glu Ser Val Asn Leu Arg Ile Ala Ala Gly Glu Thr Ile
                 440                 445                 450

 Ala Leu Leu Phe Glu Leu Ala Arg Asp Leu Glu Glu Glu Phe Val
                 455                 460                 465

 Tyr Glu Asp Met Glu Ala Leu Cys Ser Val Leu Arg Thr Leu Ala
                 470                 475                 480

 Thr Asp Ser Asn Lys Tyr Arg Ala Lys Ala Asp Arg Arg Arg Gln
                 485                 490                 495

 Arg Ser Thr Phe Arg Ala Val Leu His Ser Val Glu Gly Gly Glu
                 500                 505                 510

 Cys Glu Glu Glu Ile Val Arg Phe Gly Phe Glu Val Leu Tyr Met
                 515                 520                 525

 Asp Ser Trp Ala Arg His Arg Ile Tyr Ala Ala Phe Lys Glu Val
                 530                 535                 540

 Leu Gly Ser Gly Met His His His Leu Gln Asn Asn Glu Leu Leu
                 545                 550                 555

 Arg Asp Ile Phe Gly Leu Gly Pro Val Leu Leu Leu Asp Ala Thr
                 560                 565                 570

 Ala Leu Lys Ala Cys Lys Val Pro Arg Phe Glu Lys His Leu Tyr
                 575                 580                 585

 Asn Ala Ala Ala Phe Lys Ala Arg Thr Lys Ala Arg Ser Arg Val
                 590                 595                 600

 Arg Asp Lys Arg Ala Asp Ile Leu
                 605

<210> 1934
<211> 2857
<212> DNA
<213> Homo sapien

<400> 1934
 ggcgacgggt ttggtaagta ggaaagtttc ggttgaggag taagagctgc 50

 cgcgggagca gtaacccgcg cgggggaggc cgacgtcggt cggagagggg 100

 gtacgagagc tgctggtggt gttgtcgtgg ccggagcggc ccgcgcctgg 150

 gctgccggca cttcgcggca gtcagagcac cataacatgg tgtgggaagt 200

 gaagacaaat cagatgccta atgcagtaca gaaactcctg ttggtgatgg 250

 acaagagagc ctcaggaatg aatgactcat tggagttgct gcagtgtaat 300

 gagaatttgc catcttcacc tggatataac tcctgtgatg aacacatgga 350

 gcttgatgac cttcctgaac ttcaggcagt tcaaagtgat cctacccaat 400

 ctggcatgta ccagctgagt tcagatgttt cacatcaaga atacccaaga 450

 tcatcttgga accaaaatac ctcagacata ccagaaacta cttaccgtga 500

 aaatgaggtg gactggctaa cagaattggc aaatatcgcg accagtccac 550

 aaagtccact gatgcagtgc tcattttaca atagatcatc tcctgtacac 600

 atcatagcca ctagcaaaag tttacattcc tatgcacgcc ctccaccagt 650

 gtcctcttct tcgaagagtg aaccagcctt ccctcatcac cattggaagg 700

 aggaaacacc agtaagacat gaaagggcaa atagtgagtc agaatctggc 750

 attttctgca tgtcctccct gtcagatgat gatgatttgg gatggtgcaa 800

 ttcctggcct tcaactgtct ggcactgttt tttgaaaggc acacgactgt 850

 gctttcataa gggaagcaat aaggaatggc aagatgttga agattttgct 900

 agagctgaag gctgtgataa tgaggaagat cttcaaatgg gcattcacaa 950

 gggctatggt tctgatggtc taaagttgtt atcacatgaa gaaagtgtat 1000

 catttggcga gtctgtactg aagttgactt ttgatcctgg tacagtagaa 1050

 gatggtttac ttaccgtaga gtgtaagctg gaccaccctt tctatgttaa 1100

 aaataaaggt tggtcatcat tttatccaag cttgactgtg gtacagcatg 1150

 gcattccatg ttgtgaagtt catattggcg atgtatgtct acctcctgga 1200

 caccccgatg ccattaattt tgatgattca ggtgtttttg atacatttaa 1250

 aagctatgac ttcacaccta tggattcttc tgcagtttat gtgttaagta 1300

 gtatggctcg ccagcgtcgt gcatctttgt cttgtggagg acctggtggt 1350

 caagactttg caagatctgg attcagtaaa aactgtggct cacctggatc 1400

 atcacagctc tcttccaatt ctttgtatgc taaagctgtc aaaaaccaca 1450

 gctcagggac tgtgagtgcc acttctccta ataagtgcaa aagaccaatg 1500

 aatgccttca tgctttttgc caaaaaatac agagttgaat atactcagat 1550

 gtatccaggg aaagataaca gagccataag tgtgatcctt ggtgacaggt 1600

 ggaagaaaat gaagaatgaa gagagaagaa tgtacacatt agaagcaaag 1650

 gctttggctg aagaacagaa acgtttaaat cctgactgtt ggaagaggaa 1700

 aagaaccaat tcaggctcac aacaacatta aaccaggatg cttatgttct 1750

 taagtctata tttgcatata cattgactct tgatggaaag acttaagaag 1800

 atcaaggtct caccatttgt cctcaattcg tgtgaccata agatactgat 1850

 agcattgagt cttgaaatga tttaataata tgagtgagga tttgctttct 1900

 ccattagagc attaagctaa aactatcaac attttaaacc aaattgcctt 1950

 atttttcttc caaacttcat atatgtctat caggtaataa taggcttgaa 2000

 aattgatatc ctgtggtgct aaagtacagt agaaagagag gagaagtgta 2050

 tacatgtttt attttaaatt gtacgaaagg ggaatttaaa aaatatgtaa 2100

 ctgctgttta tacattggct ccttactgct tattaatctg tattgtacac 2150

 atgatgaaat gaagcagaag ctgggagtcg gcctttcctc tagtaaccac 2200

 cacatggctc agcatctgtg ccaaacatag gcgctcctag tctggtcagt 2250

 gccaagaggc taccagaaca tggggcaggt ggctggtgtt ggtgtcccag 2300

 cctaagagcc acctgctgca gttaccatgg catgctgagt tgatgcacca 2350

 ggtggcagca gccatccgtt attatttcca atggagacct agcccaggcc 2400

 aaggtaaagt tagttaatag cattgggata tagtcactgt aatggtgcta 2450

 ttaacaaaca gtcaacacca ttgtattttt taacttcgtg ttctgtatct 2500

 cctcagccat gtatcttaaa tatattttgt catcataatc tttctttatg 2550

 gtgggggcag actttgcact tactgcagtg caacacttgc actttaattt 2600

 tcctccaact gtctaaaatt agagcaaata cattggcaat acagctgctt 2650

 ttgctctgag ctacaatcat ggcttttcat gttacttacc aagtggtgtt 2700

 tctggttagg aatcacagct gtaaaattga tttcagttca tcacacttct 2750

 tcatgatgtt gcccctaaat tttgcacact atattcttgt atattatttc 2800

 aaataaatgg aaaaaaaagt tgcttatctc tgaaaaaaaa aaaaaaaaaa 2850

 aaaaaaa 2857

<210> 1935
<211> 514
<212> PRT
<213> Homo sapien

<400> 1935
 Met Val Trp Glu Val Lys Thr Asn Gln Met Pro Asn Ala Val Gln
   1               5                  10                  15

 Lys Leu Leu Leu Val Met Asp Lys Arg Ala Ser Gly Met Asn Asp
                  20                  25                  30

 Ser Leu Glu Leu Leu Gln Cys Asn Glu Asn Leu Pro Ser Ser Pro
                  35                  40                  45

 Gly Tyr Asn Ser Cys Asp Glu His Met Glu Leu Asp Asp Leu Pro
                  50                  55                  60

 Glu Leu Gln Ala Val Gln Ser Asp Pro Thr Gln Ser Gly Met Tyr
                  65                  70                  75

 Gln Leu Ser Ser Asp Val Ser His Gln Glu Tyr Pro Arg Ser Ser
                  80                  85                  90

 Trp Asn Gln Asn Thr Ser Asp Ile Pro Glu Thr Thr Tyr Arg Glu
                  95                 100                 105

 Asn Glu Val Asp Trp Leu Thr Glu Leu Ala Asn Ile Ala Thr Ser
                 110                 115                 120

 Pro Gln Ser Pro Leu Met Gln Cys Ser Phe Tyr Asn Arg Ser Ser
                 125                 130                 135

 Pro Val His Ile Ile Ala Thr Ser Lys Ser Leu His Ser Tyr Ala
                 140                 145                 150

 Arg Pro Pro Pro Val Ser Ser Ser Ser Lys Ser Glu Pro Ala Phe
                 155                 160                 165

 Pro His His His Trp Lys Glu Glu Thr Pro Val Arg His Glu Arg
                 170                 175                 180

 Ala Asn Ser Glu Ser Glu Ser Gly Ile Phe Cys Met Ser Ser Leu
                 185                 190                 195

 Ser Asp Asp Asp Asp Leu Gly Trp Cys Asn Ser Trp Pro Ser Thr
                 200                 205                 210

 Val Trp His Cys Phe Leu Lys Gly Thr Arg Leu Cys Phe His Lys
                 215                 220                 225

 Gly Ser Asn Lys Glu Trp Gln Asp Val Glu Asp Phe Ala Arg Ala
                 230                 235                 240

 Glu Gly Cys Asp Asn Glu Glu Asp Leu Gln Met Gly Ile His Lys
                 245                 250                 255

 Gly Tyr Gly Ser Asp Gly Leu Lys Leu Leu Ser His Glu Glu Ser
                 260                 265                 270

 Val Ser Phe Gly Glu Ser Val Leu Lys Leu Thr Phe Asp Pro Gly
                 275                 280                 285

 Thr Val Glu Asp Gly Leu Leu Thr Val Glu Cys Lys Leu Asp His
                 290                 295                 300

 Pro Phe Tyr Val Lys Asn Lys Gly Trp Ser Ser Phe Tyr Pro Ser
                 305                 310                 315

 Leu Thr Val Val Gln His Gly Ile Pro Cys Cys Glu Val His Ile
                 320                 325                 330

 Gly Asp Val Cys Leu Pro Pro Gly His Pro Asp Ala Ile Asn Phe
                 335                 340                 345

 Asp Asp Ser Gly Val Phe Asp Thr Phe Lys Ser Tyr Asp Phe Thr
                 350                 355                 360

 Pro Met Asp Ser Ser Ala Val Tyr Val Leu Ser Ser Met Ala Arg
                 365                 370                 375

 Gln Arg Arg Ala Ser Leu Ser Cys Gly Gly Pro Gly Gly Gln Asp
                 380                 385                 390

 Phe Ala Arg Ser Gly Phe Ser Lys Asn Cys Gly Ser Pro Gly Ser
                 395                 400                 405

 Ser Gln Leu Ser Ser Asn Ser Leu Tyr Ala Lys Ala Val Lys Asn
                 410                 415                 420

 His Ser Ser Gly Thr Val Ser Ala Thr Ser Pro Asn Lys Cys Lys
                 425                 430                 435

 Arg Pro Met Asn Ala Phe Met Leu Phe Ala Lys Lys Tyr Arg Val
                 440                 445                 450

 Glu Tyr Thr Gln Met Tyr Pro Gly Lys Asp Asn Arg Ala Ile Ser
                 455                 460                 465

 Val Ile Leu Gly Asp Arg Trp Lys Lys Met Lys Asn Glu Glu Arg
                 470                 475                 480

 Arg Met Tyr Thr Leu Glu Ala Lys Ala Leu Ala Glu Glu Gln Lys
                 485                 490                 495

 Arg Leu Asn Pro Asp Cys Trp Lys Arg Lys Arg Thr Asn Ser Gly
                 500                 505                 510

 Ser Gln Gln His


<210> 1936
<211> 879
<212> DNA
<213> Homo sapien

<400> 1936
 ggcacgagga tgacctggaa gtgatgccta aagctgtgga ccgcgtgggc 50

 tcgcctccct gggactaggt ttcagcggcc gctgcgatga ccaaaataaa 100

 ggcagatccc gacgggcccg aggctcaggc ggaggcgtgt tccggggagc 150

 gcacctacca ggagctgctg gtcaaccaga accccatcgc gcagcccctg 200

 gcttctcgcc gcctcacgcg gaagctctac aaatgcatca agaaagcggt 250

 gaagcagaag cagattcggc gcggggtgaa agaggttcag aaatttgtca 300

 acaaaggaga aaaagggatc atggttttgg caggagacac actgcccatt 350

 gaggtatact gccatctccc agtcatgtgt gaggaccgaa atttgcccta 400

 tgtctatatc ccctctaaga cggacctggg tgcagccgca ggctccaagc 450

 gccccacctg tgtgataatg gtcaagcccc atgaggagta ccaggaggct 500

 tacgatgagt gcctggagga ggtgcagtcc ctgcccctac ccctatgagg 550

 ggctccggta gcacctgggc acctgccgct ggaagctatt gggctggcag 600

 caggacgact ggctgtcctc ctgcccaccc acactgacgg catcttccca 650

 gttccccaag gcacgccttc ttcccaggca gctctaacag ccctttcatg 700

 aaggtaatgc tagtcttctg tccatcagtg ccatttcctg tagaactaaa 750

 ggctgttcca agaatgtggg gtggggaaag taaatgctaa gactaaaaaa 800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 879

<210> 1937
<211> 153
<212> PRT
<213> Homo sapien

<400> 1937
 Met Thr Lys Ile Lys Ala Asp Pro Asp Gly Pro Glu Ala Gln Ala
   1               5                  10                  15

 Glu Ala Cys Ser Gly Glu Arg Thr Tyr Gln Glu Leu Leu Val Asn
                  20                  25                  30

 Gln Asn Pro Ile Ala Gln Pro Leu Ala Ser Arg Arg Leu Thr Arg
                  35                  40                  45

 Lys Leu Tyr Lys Cys Ile Lys Lys Ala Val Lys Gln Lys Gln Ile
                  50                  55                  60

 Arg Arg Gly Val Lys Glu Val Gln Lys Phe Val Asn Lys Gly Glu
                  65                  70                  75

 Lys Gly Ile Met Val Leu Ala Gly Asp Thr Leu Pro Ile Glu Val
                  80                  85                  90

 Tyr Cys His Leu Pro Val Met Cys Glu Asp Arg Asn Leu Pro Tyr
                  95                 100                 105

 Val Tyr Ile Pro Ser Lys Thr Asp Leu Gly Ala Ala Ala Gly Ser
                 110                 115                 120

 Lys Arg Pro Thr Cys Val Ile Met Val Lys Pro His Glu Glu Tyr
                 125                 130                 135

 Gln Glu Ala Tyr Asp Glu Cys Leu Glu Glu Val Gln Ser Leu Pro
                 140                 145                 150

 Leu Pro Leu


<210> 1938
<211> 6836
<212> DNA
<213> Homo sapien

<400> 1938
 ctctgagggg cttagaaatt aacaggttgt ttatataatt ggccttaaat 50

 gaggtgagag tgaagagact agagccatct ctggaaaaca tcattatccc 100

 attccccggg aagctaccct ctggaactca agatttgacc atatctgttt 150

 tgaggattca ttatgaacaa agaagtctcc caggtgtgaa gtttttcaac 200

 atgagtggcc tcggggacag ttcatccgac cctgctaacc cagactcaca 250

 taagaggaaa ggatcgccat gtgacacact ggcatcaagc acggaaaaga 300

 ggcgcaggga gcaagaaaat aaatatttag aagaactagc tgagttactg 350

 tctgccaaca ttagtgacat tgacagcttg agtgtaaaac cagacaaatg 400

 caagattttg aagaaaacag tcgatcagat acagctaatg aagagaatgg 450

 aacaagagaa atcaacaact gatgacgatg tacagaaatc agacatctca 500

 tcaagtagtc aaggagtgat agaaaaggaa tccttgggac ctcttctttt 550

 ggaggctttg gatggatttt tctttgttgt gaactgtgaa gggagaattg 600

 tatttgtgtc agagaatgta accagctact taggttacaa tcaggaggaa 650

 ttaatgaata ccagcgtcta cagcatactg cacgtggggg atcatgcaga 700

 atttgtgaag aatctgctac caaaatcact agtaaatgga gttccttggc 750

 ctcaagaggc aacacgacga aatagccata cctttaactg caggatgcta 800

 attcaccctc cagatgagcc agggaccgag aaccaagaag cttgccagcg 850

 ttatgaagta atgcagtgtt tcactgtgtc acagccaaaa tcaattcaag 900

 aggatggaga agatttccag tcatgtctga tttgtattgc acggcgatta 950

 cctcggcctc cagctattac gggtgtagaa tcctttatga ccaagcaaga 1000

 tactacaggt aaaatcatct ctattgatac tagttccctg agagctgctg 1050

 gcagaactgg ttgggaagat ttagtgagga agtgcattta tgcttttttc 1100

 caacctcagg gcagagaacc atcttatgcc agacagctgt tccaagaagt 1150

 gatgactcgt ggcactgcct ccagcccctc ctatagattc atattgaatg 1200

 atgggacaat gcttagcgcc cacaccaagt gtaaactttg ctaccctcaa 1250

 agtccagaca tgcaaccttt catcatggga attcatatca tcgacaggga 1300

 gcacagtggg ctttctcctc aagatgacac taattctgga atgtcaattc 1350

 cccgagtaaa tccctcggtc aatcctagta tctctccagc tcatggtgtg 1400

 gctcgttcat ccacattgcc accatccaac agcaacatgg tatccaccag 1450

 aataaaccgc cagcagagct cagaccttca tagcagcagt catagtaatt 1500

 ctagcaacag ccaaggaagt ttcggatgct cacccggaag tcagattgta 1550

 gccaatgttg ccttaaacca aggacaggcc agttcacaga gcagtaatcc 1600

 ctctttaaac ctcaataatt ctcctatgga aggtacagga atatccctag 1650

 cacagttcat gtctccaagg agacaggtta cttctggatt ggcaacaagg 1700

 cccaggatgc caaacaattc ctttcctcct aatatttcga cattaagctc 1750

 tcccgttggc atgacaagta gtgcctgtaa taataataac cgatcttatt 1800

 caaacatccc agtaacatct ttacagggta tgaatgaagg acccaataac 1850

 tccgttggct tctctgccag ttctccagtc ctcaggcaga tgagctcaca 1900

 gaattcacct agcagattaa atatacaacc agcaaaagct gagtccaaag 1950

 ataacaaaga gattgcctca attttaaatg aaatgattca atctgacaac 2000

 agctctagtg atggcaaacc tctggattca gggcttctgc ataacaatga 2050

 cagactttca gatggagaca gtaaatactc tcaaaccagt cacaaactag 2100

 tgcagctttt gacaacaact gccgaacagc agttacggca tgctgatata 2150

 gacacaagct gcaaagatgt cctgtcttgc acaggcactt ccaactctgc 2200

 ctctgctaac tcttcaggag gttcttgtcc ctcttctcat agctcattga 2250

 cagaacggca taaaattcta caccggctct tacaggaggg tagcccctca 2300

 gatatcacca ctttgtctgt cgagcctgat aaaaaggaca gtgcatctac 2350

 ttctgtgtca gtgactggac aggtacaagg aaactccagt ataaaactag 2400

 aactggatgc ttcaaaaaaa aaagaatcaa aagaccatca gctcctacgc 2450

 tatcttttag ataaagatga gaaagattta agatcaactc caaacctgag 2500

 cctggatgat gtaaaggtga aagtggaaaa gaaagaacag atggatccat 2550

 gtaatacaaa cccaacccca atgaccaaac ccactcctga ggaaataaaa 2600

 ctggaggccc agagccagtt tacagctgac cttgaccagt ttgatcagtt 2650

 actgcccacg ctggagaagg cagcacagtt gccaggctta tgtgagacag 2700

 acaggatgga tggtgcggtc accagtgtaa ccatcaaatc ggagatcctg 2750

 ccagcttcac ttcagtccgc cactgccaga cccacttcca ggctaaatag 2800

 attacctgag ctggaattgg aagcaattga taaccaattt ggacaaccag 2850

 gaacaggcga tcagattcca tggacaaata atacagtgac agctataaat 2900

 cagagtaaat cagaagacca gtgtattagc tcacaattag atgagcttct 2950

 ctgtccaccc acaacagtag aagggagaaa tgatgagaag gctcttcttg 3000

 aacagctggt atccttcctt agtggcaaag atgaaactga gctagctgaa 3050

 ctagacagag ctctgggaat tgacaaactt gttcaggggg gtggattaga 3100

 tgtattatca gagagatttc caccacaaca agcaacgcca cctttgatca 3150

 tggaagaaag acccaacctt tattcccagc cttactcttc tccttctcct 3200

 actgccaatc tccctagccc tttccaaggc atggtcaggc aaaaaccttc 3250

 actggggacg atgcctgttc aagtaacacc tccccgaggt gctttttcac 3300

 ctggcatggg catgcagccc aggcaaactc taaacagacc tccggctgca 3350

 cctaaccagc ttcgacttca actacagcag cgattacagg gacaacagca 3400

 gttgatacac caaaatcggc aagctatctt aaaccagttt gcagcaactg 3450

 ctcctgttgg catcaatatg agatcaggca tgcaacagca aattacacct 3500

 cagccacccc tgaatgctca aatgttggca caacgtcagc gggaactgta 3550

 cagtcaacag caccgacaga ggcagctaat acagcagcaa agagccatgc 3600

 ttatgaggca gcaaagcttt gggaacaacc tccctccctc atctggacta 3650

 ccagttcaaa tggggaaccc ccgtcttcct cagggtgctc cacagcaatt 3700

 cccctatcca ccaaactatg gtacaaatcc aggaacccca cctgcttcta 3750

 ccagcccgtt ttcacaacta gcagcaaatc ctgaagcatc cttggccaac 3800

 cgcaacagca tggtgagcag aggcatgaca ggaaacatag gaggacagtt 3850

 tggcactgga atcaatcctc agatgcagca gaatgtcttc cagtatccag 3900

 gagcaggaat ggttccccaa ggtgaggcca actttgctcc atctctaagc 3950

 cctgggagct ccatggtgcc gatgccaatc cctcctcctc agagttctct 4000

 gctccagcaa actccacctg cctccgggta tcagtcacca gacatgaagg 4050

 cctggcagca aggagcgata ggaaacaaca atgtgttcag tcaagctgtc 4100

 cagaaccagc ccacgcctgc acagccagga gtatacaaca acatgagcat 4150

 caccgtttcc atggcaggtg gaaatacgaa tgttcagaac atgaacccaa 4200

 tgatggccca gatgcagatg agctctttgc agatgccagg aatgaacact 4250

 gtgtgccctg agcagataaa tgatcccgca ctgagacaca caggcctcta 4300

 ctgcaaccag ctctcatcca ctgaccttct caaaacagaa gcagatggaa 4350

 cccagcaggt gcaacaggtt caggtgtttg ctgacgtcca gtgtacagtg 4400

 aatctggtag gcggggaccc ttacctgaac cagcctggtc cactgggaac 4450

 tcaaaagccc acgtcaggac cacagacccc ccaggcccag cagaagagcc 4500

 tccttcagca gctactgact gaataaccac ttttaaagga atgtgaaatt 4550

 taaataatag acatacagag atatacaaat atattatata tttttctgag 4600

 atttttgata tctcaatctg cagccattct tcaggtcgta gcatttggag 4650

 caaaaaaaaa aaaaaaaaaa aaaaaaaagg agtttgcttt tgtcgggaga 4700

 ttgaaagatg tttttgtttc tttctttgta aaggccttgg atattgaaaa 4750

 aataccaagg cagaacagtt ggacaatcta tttcttgagc caaatttaat 4800

 tattcttatt tttgtaatca gtcattggct tcttatctgg atgaaggctt 4850

 ttggaggaga accaaaacga caagttccaa gaagaagatg aagctccgcc 4900

 tccgccgctt agtcccaacc ctgcccagga agaagggccc gtggggcttt 4950

 gcctgtgccc gtccaccaaa ggctgtcatg tgtctcgaaa tcagcagccc 5000

 tccccatccc aatcccaggc agcttgtgtg tacaatcagc ttctctagca 5050

 actctgtatc tgttggcttc aagagaatat tttgcctcca catatgtacc 5100

 ccttctcctt tttttaaaga tggatttaaa ccaagatgcc tccaggaaag 5150

 aggacgaaat gagtatattc acagaggaat ccaaaaaata cagtttgggg 5200

 gaaaatgcaa taatttttga tgagatgggt gaaggacaag aagtgagttg 5250

 tgtcaattat tgtagataca attttctgat taaatctgga aaaataaaag 5300

 gcagcctgtt ttttctgctt ttattgtatt aacagctgag gtagctaaag 5350

 ttatttaaaa taaaattaaa tttatgatcc aagtagctta tttttccctt 5400

 taaatctcat tgtaaatata tttgatttct tgtagaaatt gatttccttc 5450

 tgtttaattt tatgctttta ttatactctt gatttttcta aatttgtgtg 5500

 tgaaatataa cattgattga attgcagtta catttggtta gtaatatttc 5550

 attattttaa taactgtgat gtcatgtatg gatttacttt ggggttcaaa 5600

 tcaaaatgtc actgccagaa agagctgttc cagctgatct agagcatact 5650

 gccctagagt gtccctggga tcatctgaac agaagtgcac aggctacttg 5700

 tacagagaaa aaattaatac tcaaaggaaa tcttcatttt ttagattgac 5750

 tttgggaatt tgaattttca tcagtgcaaa tataaatttc tctatcctgc 5800

 tctgaggcta attggtacca tattttccct ttgtgtcttg tgactctgcc 5850

 acatcccatc tcatcctggc ctctgagtca agaacccagt gaactgactt 5900

 tctagttcta gaagttccgc tgcaaggcca ggaaagcttg agaaaggtat 5950

 tgtggaagaa gcaaaggtag acccccatca ctcacctttg tctgcatccc 6000

 tgggcctgtg aatgatgaca gcacctgaca ttctgcacca gctacctctg 6050

 cctccatggc agagaaaagg ccataagaac agtggaagag gagcatggac 6100

 tcagacttca aggaagaagc catttcccca ggtccttcct tctgcatctc 6150

 accaccccta gttacaaata actccattga acagcatcta ttcagaaact 6200

 atgccgaata aaaagattgg tggaagggct catgtggtta gcaactatga 6250

 aacagaaata ggacactcag ttacaaacat tatctccttt agtttttcag 6300

 aaaatgcatc cctgatttca ttcatttcca gcttgaaagc cagccatatt 6350

 actctagtcc ctaccaaact gctctagaag gtcatttcca ttttgtttgt 6400

 gatatttaga cgcgcagact tcaggaagtt cacctttaac ttcagcattc 6450

 cagatgaagt ttcctgactc agtgcttttg cataaggaac tagaaaaaaa 6500

 aagtaaggaa aattggagat gctaacatcc tcccccatcc caactgcacc 6550

 ttaaaatatg catgtcacct tcaaggtttt ataattgcac tgtttgtttt 6600

 atgtatgtac agattaaaat tattgctaca tttgaggaaa ataaaattgc 6650

 ttgcttctat gtaattcctg tcattccaca ggaaattcac ttttccagct 6700

 actgaataga atttgtttaa caacctcatg ggttgcctct tcatttacag 6750

 ggaagaaatg aaatgtacat ctgcagaaat tgccaaagcc caaattaacg 6800

 agtattataa aaggataata aagcatccct gaagcc 6836

<210> 1939
<211> 1507
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 12
<223> unknown amino acid

<400> 1939
 Leu Arg Gly Leu Glu Ile Asn Arg Leu Phe Ile Xaa Leu Ala Leu
   1               5                  10                  15

 Asn Glu Val Arg Val Lys Arg Leu Glu Pro Ser Leu Glu Asn Ile
                  20                  25                  30

 Ile Ile Pro Phe Pro Gly Lys Leu Pro Ser Gly Thr Gln Asp Leu
                  35                  40                  45

 Thr Ile Ser Val Leu Arg Ile His Tyr Glu Gln Arg Ser Leu Pro
                  50                  55                  60

 Gly Val Lys Phe Phe Asn Met Ser Gly Leu Gly Asp Ser Ser Ser
                  65                  70                  75

 Asp Pro Ala Asn Pro Asp Ser His Lys Arg Lys Gly Ser Pro Cys
                  80                  85                  90

 Asp Thr Leu Ala Ser Ser Thr Glu Lys Arg Arg Arg Glu Gln Glu
                  95                 100                 105

 Asn Lys Tyr Leu Glu Glu Leu Ala Glu Leu Leu Ser Ala Asn Ile
                 110                 115                 120

 Ser Asp Ile Asp Ser Leu Ser Val Lys Pro Asp Lys Cys Lys Ile
                 125                 130                 135

 Leu Lys Lys Thr Val Asp Gln Ile Gln Leu Met Lys Arg Met Glu
                 140                 145                 150

 Gln Glu Lys Ser Thr Thr Asp Asp Asp Val Gln Lys Ser Asp Ile
                 155                 160                 165

 Ser Ser Ser Ser Gln Gly Val Ile Glu Lys Glu Ser Leu Gly Pro
                 170                 175                 180

 Leu Leu Leu Glu Ala Leu Asp Gly Phe Phe Phe Val Val Asn Cys
                 185                 190                 195

 Glu Gly Arg Ile Val Phe Val Ser Glu Asn Val Thr Ser Tyr Leu
                 200                 205                 210

 Gly Tyr Asn Gln Glu Glu Leu Met Asn Thr Ser Val Tyr Ser Ile
                 215                 220                 225

 Leu His Val Gly Asp His Ala Glu Phe Val Lys Asn Leu Leu Pro
                 230                 235                 240

 Lys Ser Leu Val Asn Gly Val Pro Trp Pro Gln Glu Ala Thr Arg
                 245                 250                 255

 Arg Asn Ser His Thr Phe Asn Cys Arg Met Leu Ile His Pro Pro
                 260                 265                 270

 Asp Glu Pro Gly Thr Glu Asn Gln Glu Ala Cys Gln Arg Tyr Glu
                 275                 280                 285

 Val Met Gln Cys Phe Thr Val Ser Gln Pro Lys Ser Ile Gln Glu
                 290                 295                 300

 Asp Gly Glu Asp Phe Gln Ser Cys Leu Ile Cys Ile Ala Arg Arg
                 305                 310                 315

 Leu Pro Arg Pro Pro Ala Ile Thr Gly Val Glu Ser Phe Met Thr
                 320                 325                 330

 Lys Gln Asp Thr Thr Gly Lys Ile Ile Ser Ile Asp Thr Ser Ser
                 335                 340                 345

 Leu Arg Ala Ala Gly Arg Thr Gly Trp Glu Asp Leu Val Arg Lys
                 350                 355                 360

 Cys Ile Tyr Ala Phe Phe Gln Pro Gln Gly Arg Glu Pro Ser Tyr
                 365                 370                 375

 Ala Arg Gln Leu Phe Gln Glu Val Met Thr Arg Gly Thr Ala Ser
                 380                 385                 390

 Ser Pro Ser Tyr Arg Phe Ile Leu Asn Asp Gly Thr Met Leu Ser
                 395                 400                 405

 Ala His Thr Lys Cys Lys Leu Cys Tyr Pro Gln Ser Pro Asp Met
                 410                 415                 420

 Gln Pro Phe Ile Met Gly Ile His Ile Ile Asp Arg Glu His Ser
                 425                 430                 435

 Gly Leu Ser Pro Gln Asp Asp Thr Asn Ser Gly Met Ser Ile Pro
                 440                 445                 450

 Arg Val Asn Pro Ser Val Asn Pro Ser Ile Ser Pro Ala His Gly
                 455                 460                 465

 Val Ala Arg Ser Ser Thr Leu Pro Pro Ser Asn Ser Asn Met Val
                 470                 475                 480

 Ser Thr Arg Ile Asn Arg Gln Gln Ser Ser Asp Leu His Ser Ser
                 485                 490                 495

 Ser His Ser Asn Ser Ser Asn Ser Gln Gly Ser Phe Gly Cys Ser
                 500                 505                 510

 Pro Gly Ser Gln Ile Val Ala Asn Val Ala Leu Asn Gln Gly Gln
                 515                 520                 525

 Ala Ser Ser Gln Ser Ser Asn Pro Ser Leu Asn Leu Asn Asn Ser
                 530                 535                 540

 Pro Met Glu Gly Thr Gly Ile Ser Leu Ala Gln Phe Met Ser Pro
                 545                 550                 555

 Arg Arg Gln Val Thr Ser Gly Leu Ala Thr Arg Pro Arg Met Pro
                 560                 565                 570

 Asn Asn Ser Phe Pro Pro Asn Ile Ser Thr Leu Ser Ser Pro Val
                 575                 580                 585

 Gly Met Thr Ser Ser Ala Cys Asn Asn Asn Asn Arg Ser Tyr Ser
                 590                 595                 600

 Asn Ile Pro Val Thr Ser Leu Gln Gly Met Asn Glu Gly Pro Asn
                 605                 610                 615

 Asn Ser Val Gly Phe Ser Ala Ser Ser Pro Val Leu Arg Gln Met
                 620                 625                 630

 Ser Ser Gln Asn Ser Pro Ser Arg Leu Asn Ile Gln Pro Ala Lys
                 635                 640                 645

 Ala Glu Ser Lys Asp Asn Lys Glu Ile Ala Ser Ile Leu Asn Glu
                 650                 655                 660

 Met Ile Gln Ser Asp Asn Ser Ser Ser Asp Gly Lys Pro Leu Asp
                 665                 670                 675

 Ser Gly Leu Leu His Asn Asn Asp Arg Leu Ser Asp Gly Asp Ser
                 680                 685                 690

 Lys Tyr Ser Gln Thr Ser His Lys Leu Val Gln Leu Leu Thr Thr
                 695                 700                 705

 Thr Ala Glu Gln Gln Leu Arg His Ala Asp Ile Asp Thr Ser Cys
                 710                 715                 720

 Lys Asp Val Leu Ser Cys Thr Gly Thr Ser Asn Ser Ala Ser Ala
                 725                 730                 735

 Asn Ser Ser Gly Gly Ser Cys Pro Ser Ser His Ser Ser Leu Thr
                 740                 745                 750

 Glu Arg His Lys Ile Leu His Arg Leu Leu Gln Glu Gly Ser Pro
                 755                 760                 765

 Ser Asp Ile Thr Thr Leu Ser Val Glu Pro Asp Lys Lys Asp Ser
                 770                 775                 780

 Ala Ser Thr Ser Val Ser Val Thr Gly Gln Val Gln Gly Asn Ser
                 785                 790                 795

 Ser Ile Lys Leu Glu Leu Asp Ala Ser Lys Lys Lys Glu Ser Lys
                 800                 805                 810

 Asp His Gln Leu Leu Arg Tyr Leu Leu Asp Lys Asp Glu Lys Asp
                 815                 820                 825

 Leu Arg Ser Thr Pro Asn Leu Ser Leu Asp Asp Val Lys Val Lys
                 830                 835                 840

 Val Glu Lys Lys Glu Gln Met Asp Pro Cys Asn Thr Asn Pro Thr
                 845                 850                 855

 Pro Met Thr Lys Pro Thr Pro Glu Glu Ile Lys Leu Glu Ala Gln
                 860                 865                 870

 Ser Gln Phe Thr Ala Asp Leu Asp Gln Phe Asp Gln Leu Leu Pro
                 875                 880                 885

 Thr Leu Glu Lys Ala Ala Gln Leu Pro Gly Leu Cys Glu Thr Asp
                 890                 895                 900

 Arg Met Asp Gly Ala Val Thr Ser Val Thr Ile Lys Ser Glu Ile
                 905                 910                 915

 Leu Pro Ala Ser Leu Gln Ser Ala Thr Ala Arg Pro Thr Ser Arg
                 920                 925                 930

 Leu Asn Arg Leu Pro Glu Leu Glu Leu Glu Ala Ile Asp Asn Gln
                 935                 940                 945

 Phe Gly Gln Pro Gly Thr Gly Asp Gln Ile Pro Trp Thr Asn Asn
                 950                 955                 960

 Thr Val Thr Ala Ile Asn Gln Ser Lys Ser Glu Asp Gln Cys Ile
                 965                 970                 975

 Ser Ser Gln Leu Asp Glu Leu Leu Cys Pro Pro Thr Thr Val Glu
                 980                 985                 990

 Gly Arg Asn Asp Glu Lys Ala Leu Leu Glu Gln Leu Val Ser Phe
                 995                1000                1005

 Leu Ser Gly Lys Asp Glu Thr Glu Leu Ala Glu Leu Asp Arg Ala
                1010                1015                1020

 Leu Gly Ile Asp Lys Leu Val Gln Gly Gly Gly Leu Asp Val Leu
                1025                1030                1035

 Ser Glu Arg Phe Pro Pro Gln Gln Ala Thr Pro Pro Leu Ile Met
                1040                1045                1050

 Glu Glu Arg Pro Asn Leu Tyr Ser Gln Pro Tyr Ser Ser Pro Ser
                1055                1060                1065

 Pro Thr Ala Asn Leu Pro Ser Pro Phe Gln Gly Met Val Arg Gln
                1070                1075                1080

 Lys Pro Ser Leu Gly Thr Met Pro Val Gln Val Thr Pro Pro Arg
                1085                1090                1095

 Gly Ala Phe Ser Pro Gly Met Gly Met Gln Pro Arg Gln Thr Leu
                1100                1105                1110

 Asn Arg Pro Pro Ala Ala Pro Asn Gln Leu Arg Leu Gln Leu Gln
                1115                1120                1125

 Gln Arg Leu Gln Gly Gln Gln Gln Leu Ile His Gln Asn Arg Gln
                1130                1135                1140

 Ala Ile Leu Asn Gln Phe Ala Ala Thr Ala Pro Val Gly Ile Asn
                1145                1150                1155

 Met Arg Ser Gly Met Gln Gln Gln Ile Thr Pro Gln Pro Pro Leu
                1160                1165                1170

 Asn Ala Gln Met Leu Ala Gln Arg Gln Arg Glu Leu Tyr Ser Gln
                1175                1180                1185

 Gln His Arg Gln Arg Gln Leu Ile Gln Gln Gln Arg Ala Met Leu
                1190                1195                1200

 Met Arg Gln Gln Ser Phe Gly Asn Asn Leu Pro Pro Ser Ser Gly
                1205                1210                1215

 Leu Pro Val Gln Met Gly Asn Pro Arg Leu Pro Gln Gly Ala Pro
                1220                1225                1230

 Gln Gln Phe Pro Tyr Pro Pro Asn Tyr Gly Thr Asn Pro Gly Thr
                1235                1240                1245

 Pro Pro Ala Ser Thr Ser Pro Phe Ser Gln Leu Ala Ala Asn Pro
                1250                1255                1260

 Glu Ala Ser Leu Ala Asn Arg Asn Ser Met Val Ser Arg Gly Met
                1265                1270                1275

 Thr Gly Asn Ile Gly Gly Gln Phe Gly Thr Gly Ile Asn Pro Gln
                1280                1285                1290

 Met Gln Gln Asn Val Phe Gln Tyr Pro Gly Ala Gly Met Val Pro
                1295                1300                1305

 Gln Gly Glu Ala Asn Phe Ala Pro Ser Leu Ser Pro Gly Ser Ser
                1310                1315                1320

 Met Val Pro Met Pro Ile Pro Pro Pro Gln Ser Ser Leu Leu Gln
                1325                1330                1335

 Gln Thr Pro Pro Ala Ser Gly Tyr Gln Ser Pro Asp Met Lys Ala
                1340                1345                1350

 Trp Gln Gln Gly Ala Ile Gly Asn Asn Asn Val Phe Ser Gln Ala
                1355                1360                1365

 Val Gln Asn Gln Pro Thr Pro Ala Gln Pro Gly Val Tyr Asn Asn
                1370                1375                1380

 Met Ser Ile Thr Val Ser Met Ala Gly Gly Asn Thr Asn Val Gln
                1385                1390                1395

 Asn Met Asn Pro Met Met Ala Gln Met Gln Met Ser Ser Leu Gln
                1400                1405                1410

 Met Pro Gly Met Asn Thr Val Cys Pro Glu Gln Ile Asn Asp Pro
                1415                1420                1425

 Ala Leu Arg His Thr Gly Leu Tyr Cys Asn Gln Leu Ser Ser Thr
                1430                1435                1440

 Asp Leu Leu Lys Thr Glu Ala Asp Gly Thr Gln Gln Val Gln Gln
                1445                1450                1455

 Val Gln Val Phe Ala Asp Val Gln Cys Thr Val Asn Leu Val Gly
                1460                1465                1470

 Gly Asp Pro Tyr Leu Asn Gln Pro Gly Pro Leu Gly Thr Gln Lys
                1475                1480                1485

 Pro Thr Ser Gly Pro Gln Thr Pro Gln Ala Gln Gln Lys Ser Leu
                1490                1495                1500

 Leu Gln Gln Leu Leu Thr Glu
                1505

<210> 1940
<211> 2422
<212> DNA
<213> Homo sapien

<400> 1940
 gtcagcctcc cttccaccgc catattgggc cactaaaaaa agggggctcg 50

 tcttttcggg gtgtttttct ccccctcccc tgtccccgct tgctcacggc 100

 tctgcgactc cgacgccggc aaggtttgga gagcggctgg gttcgcggga 150

 cccgcgggct tgcacccgcc cagactcgga cgggctttgc caccctctcc 200

 gcttgcctgg tcccctctcc tctccgccct cccgctcgcc agtccatttg 250

 atcagcggag actcggcggc cgggccgggg cttccccgca gcccctgcgc 300

 gctcctagag ctcgggccgt ggctcgtcgg ggtctgtgtc ttttggctcc 350

 gagggcagtc gctgggcttc cgagaggggt tcgggccgcg taggggcgct 400

 ttgttttgtt cggttttgtt tttttgagag tgcgagagag gcggtcgtgc 450

 agacccggga gaaagatgtc aaacgtgcga gtgtctaacg ggagccctag 500

 cctggagcgg atggacgcca ggcaggcgga gcaccccaag ccctcggcct 550

 gcaggaacct cttcggcccg gtggaccacg aagagttaac ccgggacttg 600

 gagaagcact gcagagacat ggaagaggcg agccagcgca agtggaattt 650

 cgattttcag aatcacaaac ccctagaggg caagtacgag tggcaagagg 700

 tggagaaggg cagcttgccc gagttctact acagaccccc gcggcccccc 750

 aaaggtgcct gcaaggtgcc ggcgcaggag agccaggatg tcagcgggag 800

 ccgcccggcg gcgcctttaa ttggggctcc ggctaactct gaggacacgc 850

 atttggtgga cccaaagact gatccgtcgg acagccagac ggggttagcg 900

 gagcaatgcg caggaataag gaagcgacct gcaaccgacg attcttctac 950

 tcaaaacaaa agagccaaca gaacagaaga aaatgtttca gacggttccc 1000

 caaatgccgg ttctgtggag cagacgccca agaagcctgg cctcagaaga 1050

 cgtcaaacgt aaacagctcg aattaagaat atgtttcctt gtttatcaga 1100

 tacatcactg cttgatgaag caaggaagat atacatgaaa attttaaaaa 1150

 tacatatcgc tgacttcatg gaatggacat cctgtataag cactgaaaaa 1200

 caacaacaca ataacactaa aattttaggc actcttaaat gatctgcctc 1250

 taaaagcgtt ggatgtagca ttatgcaatt aggtttttcc ttatttgctt 1300

 cattgtacta cctgtgtata tagtttttac cttttatgta gcacataaac 1350

 tttggggaag ggagggcagg gtggggctga ggaactgacg tggagcgggg 1400

 tatgaagagc ttgctttgat ttacagcaag tagataaata tttgacttgc 1450

 atgaagagaa gcaattttgg ggaagggttt gaattgtttt ctttaaagat 1500

 gtaatgtccc tttcagagac agctgatact tcatttaaaa aaatcacaaa 1550

 aatttgaaca ctggctaaag ataattgcta tttattttta caagaagttt 1600

 attctcattt gggagatctg gtgatctccc aagctatcta aagtttgtta 1650

 gatagctgca tgtggctttt ttaaaaaagc aacagaaacc tatcctcact 1700

 gccctcccca gtctctctta aagttggaat ttaccagtta attactcagc 1750

 agaatggtga tcactccagg tagtttgggg caaaaatccg aggtgcttgg 1800

 gagttttgaa tgttaagaat tgaccatctg cttttattaa atttgttgac 1850

 aaaattttct cattttcttt tcacttcggg ctgtgtaaac acagtcaaaa 1900

 taattctaaa tccctcgata tttttaaaga tctgtaagta acttcacatt 1950

 aaaaaatgaa atatttttta atttaaagct tactctgtcc atttatccac 2000

 aggaaagtgt tatttttaaa ggaaggttca tgtagagaaa agcacacttg 2050

 taggataagt gaaatggata ctacatcttt aaacagtatt tcattgcctg 2100

 tgtatggaaa aaccatttga agtgtacctg tgtacataac tctgtaaaaa 2150

 cactgaaaaa ttatactaac ttatttatgt taaaagattt tttttaatct 2200

 agacaatata caagccaaag tggcatgttt tgtgcatttg taaatgctgt 2250

 gttgggtaga ataggttttc ccctcttttg ttaaataata tggctatgct 2300

 taaaaggttg catactgagc caagtataat tttttgtaat gtgtgaaaaa 2350

 gatgccaatt attgttacac attaagtaat caataaagaa aacttccata 2400

 gctaaaaaaa aaaaaaaaaa aa 2422

<210> 1941
<211> 198
<212> PRT
<213> Homo sapien

<400> 1941
 Met Ser Asn Val Arg Val Ser Asn Gly Ser Pro Ser Leu Glu Arg
   1               5                  10                  15

 Met Asp Ala Arg Gln Ala Glu His Pro Lys Pro Ser Ala Cys Arg
                  20                  25                  30

 Asn Leu Phe Gly Pro Val Asp His Glu Glu Leu Thr Arg Asp Leu
                  35                  40                  45

 Glu Lys His Cys Arg Asp Met Glu Glu Ala Ser Gln Arg Lys Trp
                  50                  55                  60

 Asn Phe Asp Phe Gln Asn His Lys Pro Leu Glu Gly Lys Tyr Glu
                  65                  70                  75

 Trp Gln Glu Val Glu Lys Gly Ser Leu Pro Glu Phe Tyr Tyr Arg
                  80                  85                  90

 Pro Pro Arg Pro Pro Lys Gly Ala Cys Lys Val Pro Ala Gln Glu
                  95                 100                 105

 Ser Gln Asp Val Ser Gly Ser Arg Pro Ala Ala Pro Leu Ile Gly
                 110                 115                 120

 Ala Pro Ala Asn Ser Glu Asp Thr His Leu Val Asp Pro Lys Thr
                 125                 130                 135

 Asp Pro Ser Asp Ser Gln Thr Gly Leu Ala Glu Gln Cys Ala Gly
                 140                 145                 150

 Ile Arg Lys Arg Pro Ala Thr Asp Asp Ser Ser Thr Gln Asn Lys
                 155                 160                 165

 Arg Ala Asn Arg Thr Glu Glu Asn Val Ser Asp Gly Ser Pro Asn
                 170                 175                 180

 Ala Gly Ser Val Glu Gln Thr Pro Lys Lys Pro Gly Leu Arg Arg
                 185                 190                 195

 Arg Gln Thr


<210> 1942
<211> 1916
<212> DNA
<213> Homo sapien

<400> 1942
 ggcacgaggg ccggagtcgt cttcgggacg cgcctgctct tcgcctttcg 50

 ctgcagtccg tcgatttctt tctccaggaa gaaaaatggc atccgttgca 100

 gttgatccac aaccgagtgt ggtgactcgg gtggtcaacc tgcccttggt 150

 gagctccacg tatgacctca tgtcctcagc ctatctcagt acaaaggacc 200

 agtatcccta cctgaagtct gtgtgtgaga tggcagagaa cggtgtgaag 250

 accatcacct ccgtggccat gaccagtgct ctgcccatca tccagaagct 300

 agagccgcaa attgcagttg ccaataccta tgcctgtaag gggctagaca 350

 ggattgagga gagactgcct attctgaatc agccatcaac tcagattgtt 400

 gccaatgcca aaggcgctgt gactggggca aaagatgctg tgacgactac 450

 tgtgactggg gccaaggatt ctgtggccag cacgatcaca ggggtgatgg 500

 acaagaccaa aggggcagtg actggcagtg tggagaagac caagtctgtg 550

 gtcagtggca gcattaacac agtcttgggg agtcggatga tgcagctcgt 600

 gagcagtggc gtagaaaatg cactcaccaa atcagagctg ttggtagaac 650

 agtacctccc tctcactgag gaagaactag aaaaagaagc aaaaaaagtt 700

 gaaggatttg atctggttca gaagccaagt tattatgtta gactgggatc 750

 cctgtctacc aagcttcact cccgtgccta ccagcaggct ctcagcaggg 800

 ttaaagaagc taagcaaaaa agccaacaga ccatttctca gctccattct 850

 actgttcacc tgattgaatt tgccaggaag aatgtgtata gtgccaatca 900

 gaaaattcag gatgctcagg ataagctcta cctctcatgg gtagagtgga 950

 aaaggagcat tggatatgat gatactgatg agtcccactg tgctgagcac 1000

 attgagtcac gtactcttgc aattgcccgc aacctgactc agcagctcca 1050

 gaccacgtgc cacaccctcc tgtccaacat ccaaggtgta ccacagaaca 1100

 tccaagatca agccaagcac atgggggtga tggcaggcga catctactca 1150

 gtgttccgca atgctgcctc ctttaaagaa gtgtctgaca gcctcctcac 1200

 ttctagcaag gggcagctgc agaaaatgaa ggaatcttta gatgacgtga 1250

 tggattatct tgttaacaac acgcccctca actggctggt aggtcccttt 1300

 tatcctcagc tgactgagtc tcagaatgct caggaccaag gtgcagagat 1350

 ggacaagagc agccaggaga cccagcgatc tgagcataaa actcattaaa 1400

 cctgccccta tcactagtgc atgctgtggc cagacagatg acaccttttg 1450

 ttatgttgaa attaacttgc taggcaaccc taaattggga agcaagtagc 1500

 tagtataaag gccctcaatt gtagttgttt ccagctgaat taagagcttt 1550

 aaagtttctg gcattagcag atgatttctg ttcacctggt aagaaaagaa 1600

 tgataggctt gtcagagcct atagccagaa ctcagaaaaa attcaaatgc 1650

 acttatgttc tcattctatg gccattgtgt tgcctctgtt actgtttgta 1700

 ttgaataaaa acatcttcat gtgggctggg gtagaaactg gtgtctgctc 1750

 tggtgtgatc tgaaaaggcg tcttcactgc tttatctcat gatgcttgct 1800

 tgtaaaactt gattttagtt tttcatttct caaataggaa tactaccttt 1850

 gaattcaata aaattcactg caggataaat aaaaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaa 1916

<210> 1943
<211> 437
<212> PRT
<213> Homo sapien

<400> 1943
 Met Ala Ser Val Ala Val Asp Pro Gln Pro Ser Val Val Thr Arg
   1               5                  10                  15

 Val Val Asn Leu Pro Leu Val Ser Ser Thr Tyr Asp Leu Met Ser
                  20                  25                  30

 Ser Ala Tyr Leu Ser Thr Lys Asp Gln Tyr Pro Tyr Leu Lys Ser
                  35                  40                  45

 Val Cys Glu Met Ala Glu Asn Gly Val Lys Thr Ile Thr Ser Val
                  50                  55                  60

 Ala Met Thr Ser Ala Leu Pro Ile Ile Gln Lys Leu Glu Pro Gln
                  65                  70                  75

 Ile Ala Val Ala Asn Thr Tyr Ala Cys Lys Gly Leu Asp Arg Ile
                  80                  85                  90

 Glu Glu Arg Leu Pro Ile Leu Asn Gln Pro Ser Thr Gln Ile Val
                  95                 100                 105

 Ala Asn Ala Lys Gly Ala Val Thr Gly Ala Lys Asp Ala Val Thr
                 110                 115                 120

 Thr Thr Val Thr Gly Ala Lys Asp Ser Val Ala Ser Thr Ile Thr
                 125                 130                 135

 Gly Val Met Asp Lys Thr Lys Gly Ala Val Thr Gly Ser Val Glu
                 140                 145                 150

 Lys Thr Lys Ser Val Val Ser Gly Ser Ile Asn Thr Val Leu Gly
                 155                 160                 165

 Ser Arg Met Met Gln Leu Val Ser Ser Gly Val Glu Asn Ala Leu
                 170                 175                 180

 Thr Lys Ser Glu Leu Leu Val Glu Gln Tyr Leu Pro Leu Thr Glu
                 185                 190                 195

 Glu Glu Leu Glu Lys Glu Ala Lys Lys Val Glu Gly Phe Asp Leu
                 200                 205                 210

 Val Gln Lys Pro Ser Tyr Tyr Val Arg Leu Gly Ser Leu Ser Thr
                 215                 220                 225

 Lys Leu His Ser Arg Ala Tyr Gln Gln Ala Leu Ser Arg Val Lys
                 230                 235                 240

 Glu Ala Lys Gln Lys Ser Gln Gln Thr Ile Ser Gln Leu His Ser
                 245                 250                 255

 Thr Val His Leu Ile Glu Phe Ala Arg Lys Asn Val Tyr Ser Ala
                 260                 265                 270

 Asn Gln Lys Ile Gln Asp Ala Gln Asp Lys Leu Tyr Leu Ser Trp
                 275                 280                 285

 Val Glu Trp Lys Arg Ser Ile Gly Tyr Asp Asp Thr Asp Glu Ser
                 290                 295                 300

 His Cys Ala Glu His Ile Glu Ser Arg Thr Leu Ala Ile Ala Arg
                 305                 310                 315

 Asn Leu Thr Gln Gln Leu Gln Thr Thr Cys His Thr Leu Leu Ser
                 320                 325                 330

 Asn Ile Gln Gly Val Pro Gln Asn Ile Gln Asp Gln Ala Lys His
                 335                 340                 345

 Met Gly Val Met Ala Gly Asp Ile Tyr Ser Val Phe Arg Asn Ala
                 350                 355                 360

 Ala Ser Phe Lys Glu Val Ser Asp Ser Leu Leu Thr Ser Ser Lys
                 365                 370                 375

 Gly Gln Leu Gln Lys Met Lys Glu Ser Leu Asp Asp Val Met Asp
                 380                 385                 390

 Tyr Leu Val Asn Asn Thr Pro Leu Asn Trp Leu Val Gly Pro Phe
                 395                 400                 405

 Tyr Pro Gln Leu Thr Glu Ser Gln Asn Ala Gln Asp Gln Gly Ala
                 410                 415                 420

 Glu Met Asp Lys Ser Ser Gln Glu Thr Gln Arg Ser Glu His Lys
                 425                 430                 435

 Thr His


<210> 1944
<211> 1641
<212> DNA
<213> Homo sapien

<400> 1944
 tcagcgggag gggctggacc ccgcgttcct cctccctgcc ggtccccatc 50

 cttaaagcga gagtctggac gccccgcctg tgggagagag cgccgggatc 100

 cggacgggga gcaaccgggg caggccgtgc cggctgagga ggtcctgagg 150

 ctacagagct gccgcggctg gcacacgagc gcctcggcac taaccgagtg 200

 ttcgcggggg ctgtgagggg agggccccgg gcgccattgc tggcggtggg 250

 agcgccgccc ggtctcagcc cgccctcggc tgctctcctc ctccggctgg 300

 gaggggccgt agctcggggc cgtcgccagc cccggcccgg gctcgagaat 350

 caagggcctc ggccgccgtc ccgcagctca gtccatcgcc cttgccgggc 400

 agcccgggca gagaccatgt ttgacaagac gcggctgccg tacgtggccc 450

 tcgatgtgct ctgcgtgttg ctggcttcca tgcctatggc tgttctaaaa 500

 ttgggccaaa tatatccatt tcagagaggc tttttctgta aagacaacag 550

 catcaactat ccgtaccatg acagtaccgt cacatccact gtcctcatcc 600

 tagtgggggt tggcttgccc atttcctcta ttattcttgg agaaaccctg 650

 tctgtttact gtaacctttt gcactcaaat tcctttatca ggaataacta 700

 catagccact atttacaaag ccattggaac ctttttattt ggtgcagctg 750

 ctagtcagtc cctgactgac attgccaagt attcaatagg cagactgcgg 800

 cctcacttct tggatgtttg tgatccagat tggtcaaaaa tcaactgcag 850

 cgatggttac attgaatact acatatgtcg agggaatgca gaaagagtta 900

 aggaaggcag gttgtccttc tattcaggcc actcttcgtt ttccatgtac 950

 tgcatgctgt ttgtggcact ttatcttcaa gccaggatga agggagactg 1000

 ggcaagactc ttacgcccca cactgcaatt tggtcttgtt gccgtatcca 1050

 tttatgtggg cctttctcga gtttctgatt ataaacacca ctggagcgat 1100

 gtgttgactg gactcattca gggagctctg gttgcaatat tagttgctgt 1150

 atatgtatcg gatttcttca aagaaagaac ttcttttaaa gaaagaaaag 1200

 aggaggactc tcatacaact ctgcatgaaa caccaacaac tgggaatcac 1250

 tatccgagca atcaccagcc ttgaaaggca gcagggtgcc caggtgaagc 1300

 tggcctgttt tctaaaggaa aatgattgcc acaaggcaag aggatgcatc 1350

 tttcttcctg gtgtacaagc ctttaaagac ttctgctgct gctatgcctc 1400

 ttggatgcac actttgtgtg tacatagtta cctttaactc agtggttatc 1450

 taatagctct aaactcatta aaaaaactcc aagccttcca ccaaaacagt 1500

 gccccacctg tatacatttt tattaaaaaa atgtaatgct tatgtataaa 1550

 catgtatgta atatgctttc tatgaatgat gtttgattta aatataatac 1600

 atattaaaat gtatgggaga accaaaaaaa aaaaaaaaaa a 1641

<210> 1945
<211> 285
<212> PRT
<213> Homo sapien

<400> 1945
 Met Phe Asp Lys Thr Arg Leu Pro Tyr Val Ala Leu Asp Val Leu
   1               5                  10                  15

 Cys Val Leu Leu Ala Ser Met Pro Met Ala Val Leu Lys Leu Gly
                  20                  25                  30

 Gln Ile Tyr Pro Phe Gln Arg Gly Phe Phe Cys Lys Asp Asn Ser
                  35                  40                  45

 Ile Asn Tyr Pro Tyr His Asp Ser Thr Val Thr Ser Thr Val Leu
                  50                  55                  60

 Ile Leu Val Gly Val Gly Leu Pro Ile Ser Ser Ile Ile Leu Gly
                  65                  70                  75

 Glu Thr Leu Ser Val Tyr Cys Asn Leu Leu His Ser Asn Ser Phe
                  80                  85                  90

 Ile Arg Asn Asn Tyr Ile Ala Thr Ile Tyr Lys Ala Ile Gly Thr
                  95                 100                 105

 Phe Leu Phe Gly Ala Ala Ala Ser Gln Ser Leu Thr Asp Ile Ala
                 110                 115                 120

 Lys Tyr Ser Ile Gly Arg Leu Arg Pro His Phe Leu Asp Val Cys
                 125                 130                 135

 Asp Pro Asp Trp Ser Lys Ile Asn Cys Ser Asp Gly Tyr Ile Glu
                 140                 145                 150

 Tyr Tyr Ile Cys Arg Gly Asn Ala Glu Arg Val Lys Glu Gly Arg
                 155                 160                 165

 Leu Ser Phe Tyr Ser Gly His Ser Ser Phe Ser Met Tyr Cys Met
                 170                 175                 180

 Leu Phe Val Ala Leu Tyr Leu Gln Ala Arg Met Lys Gly Asp Trp
                 185                 190                 195

 Ala Arg Leu Leu Arg Pro Thr Leu Gln Phe Gly Leu Val Ala Val
                 200                 205                 210

 Ser Ile Tyr Val Gly Leu Ser Arg Val Ser Asp Tyr Lys His His
                 215                 220                 225

 Trp Ser Asp Val Leu Thr Gly Leu Ile Gln Gly Ala Leu Val Ala
                 230                 235                 240

 Ile Leu Val Ala Val Tyr Val Ser Asp Phe Phe Lys Glu Arg Thr
                 245                 250                 255

 Ser Phe Lys Glu Arg Lys Glu Glu Asp Ser His Thr Thr Leu His
                 260                 265                 270

 Glu Thr Pro Thr Thr Gly Asn His Tyr Pro Ser Asn His Gln Pro
                 275                 280                 285

<210> 1946
<211> 2765
<212> DNA
<213> Homo sapien

<400> 1946
 ggcacgaggg aaagggagtg ttcgggtttc gctggggcct cgcggctcca 50

 gagcccagca tggcttcctc gcgagcctct tccacgcagg caaccaaaac 100

 taaagcaccc gacgacttag ttgctccggt cgtgaagaaa ccacacatct 150

 attatggaag tttggaagag aaggagaggg agcgtctggc caaaggagag 200

 tctgggattt tggggaaaga cggacttaaa gcagggatcg aagctggaaa 250

 tattaatata acctctggag aagtgtttga aattgaagag catatcagcg 300

 agcgacaggc agaagtattg gctgagtttg agagaaggaa gcgagcccgg 350

 cagatcaatg tttccacaga tgactcagag gtcaaagctt gccttagagc 400

 cttgggggaa cccatcacac tttttggaga gggtcctgct gaaagaagag 450

 aaaggttaag aaatatcctc tcagttgtcg gtactgatgc cttgaaaaag 500

 accaaaaagg atgatgagaa gtctaaaaag tccaaagaag agtatcagca 550

 aacctggtat catgaaggac caaatagctt gaaggtggca agactatgga 600

 ttgctaatta ttcgttgccc agggcaatga aacgcttgga agaggcccga 650

 ctccataagg agattcctga gacaacaagg acctcccaga tgcaagagct 700

 gcacaagtct ctccggtctt tgaataattt ttgcagtcag attggggatg 750

 atcggcctat ctcctactgt cactttagtc ccaattccaa gatgctggcc 800

 acagcttgtt ggagtgggct ttgcaagctc tggtctgttc ctgattgcaa 850

 cctccttcac actcttcgag ggcataacac aaatgtagga gcaattgtat 900

 tccatcccaa atccactgtc tccttggacc caaaagatgt caacctggcc 950

 tcttgtgcgg ctgatggctc tgtgaagctt tggagtctcg acagtgatga 1000

 accagtggca gatattgaag gccatacagt gcgtgtggcg cgggtaatgt 1050

 ggcatccttc aggacgtttc ctgggcacca cctgctatga ccgttcatgg 1100

 cgcttatggg atttggaggc tcaagaggag atcctgcatc aggaaggcca 1150

 tagcatgggt gtgtatgaca ttgccttcca tcaagatggc tctttggctg 1200

 gcactggggg actggatgca tttggtcgag tttgggacct acgcacagga 1250

 cgttgtatca tgttcttaga aggccacctg aaagaaatct atggaataaa 1300

 tttctccccc aatggctatc acattgcaac cggcagtggt gacaacacct 1350

 gcaaagtgtg ggacctccga cagcggcgtt gcgtctacac catccctgct 1400

 catcagaact tagtgactgg tgtcaagttt gagcctatcc atgggaactt 1450

 cttgcttact ggtgcctatg ataacacagc caagatctgg acgcacccag 1500

 gctggtcccc gctgaagact ctggctggcc acgaaggcaa agtgatgggc 1550

 ctagatattt cttccgatgg gcagctcata gccacttgct catatgacag 1600

 gaccttcaag ctgtggatgg ctgaatagat gacaatggga aaaggacttg 1650

 aacctcaagc tctctctaag gagctgtttt cctcaaacga gaagaattga 1700

 agtgtttagt tctatcatgt tttctgccaa ttaccatgca tagaccctca 1750

 gtagaattgg atttccatgt cagcccccac tccaggaagg cagcccaatc 1800

 cctaggtgat ggggaacccc tctcacggtt gaaaatttat taccttttta 1850

 cgccctgcca cgaactgtgt agacattgtt tttattaatc ttttgtttgg 1900

 ccgggcgtgg tggctcacgc ctgtaatcct agcactttgg gaggccgagg 1950

 tgggtagatc gcttgagctc aggagttcaa gacgagcctg ggcaacatgg 2000

 caaatgccgt ctctgcaaaa aaatactaaa attagctggt cgcggtggct 2050

 tctgcctgtg attccggcta cttgggaggc tgaggtggga gggattgctt 2100

 aagcctggga ggcagaggtt gcagtgagcc gagattgcgc cattgcactc 2150

 tagcctgtgt gacagagcaa gaccctgtct caaaaaaaaa aaaaatttgt 2200

 tcgaatgcct tatagccttc ctcacagcac ccaggattgt gactgactct 2250

 gcatttttaa ttcttgaaac ttggctttcc ataacatggt acatgcttca 2300

 ggactacata tgacccagag agcaaggtgg ctgaactata gtctggaagc 2350

 cctcaggtaa agaggcacat ctcaccactc attggttaaa caatgcatca 2400

 tagcgagcac ttttcctttc cctggagaat gggatgtgaa gcagtagacc 2450

 gcagccacgc cgatggttat acagtgaaga agacttcacc tcttcctatt 2500

 gagtttgctt ggaatgctga cagcatcagg caactctgaa ctgaacattt 2550

 gctttgtcag aaaatatctt tttttttact ttgaagtttg gcaaccttca 2600

 tgttacccca aagcaaaacc attgtgtcag gagtcaaaca aatgtttaga 2650

 aagcaaacat gacgtctcta ttgtacaacc tcctttctct tggctgttta 2700

 aaggatgtac ttcgtgtatt aaagggtact ttatgttgaa gtaaaaaaaa 2750

 aaaaaaaaaa aaaaa 2765

<210> 1947
<211> 522
<212> PRT
<213> Homo sapien

<400> 1947
 Met Ala Ser Ser Arg Ala Ser Ser Thr Gln Ala Thr Lys Thr Lys
   1               5                  10                  15

 Ala Pro Asp Asp Leu Val Ala Pro Val Val Lys Lys Pro His Ile
                  20                  25                  30

 Tyr Tyr Gly Ser Leu Glu Glu Lys Glu Arg Glu Arg Leu Ala Lys
                  35                  40                  45

 Gly Glu Ser Gly Ile Leu Gly Lys Asp Gly Leu Lys Ala Gly Ile
                  50                  55                  60

 Glu Ala Gly Asn Ile Asn Ile Thr Ser Gly Glu Val Phe Glu Ile
                  65                  70                  75

 Glu Glu His Ile Ser Glu Arg Gln Ala Glu Val Leu Ala Glu Phe
                  80                  85                  90

 Glu Arg Arg Lys Arg Ala Arg Gln Ile Asn Val Ser Thr Asp Asp
                  95                 100                 105

 Ser Glu Val Lys Ala Cys Leu Arg Ala Leu Gly Glu Pro Ile Thr
                 110                 115                 120

 Leu Phe Gly Glu Gly Pro Ala Glu Arg Arg Glu Arg Leu Arg Asn
                 125                 130                 135

 Ile Leu Ser Val Val Gly Thr Asp Ala Leu Lys Lys Thr Lys Lys
                 140                 145                 150

 Asp Asp Glu Lys Ser Lys Lys Ser Lys Glu Glu Tyr Gln Gln Thr
                 155                 160                 165

 Trp Tyr His Glu Gly Pro Asn Ser Leu Lys Val Ala Arg Leu Trp
                 170                 175                 180

 Ile Ala Asn Tyr Ser Leu Pro Arg Ala Met Lys Arg Leu Glu Glu
                 185                 190                 195

 Ala Arg Leu His Lys Glu Ile Pro Glu Thr Thr Arg Thr Ser Gln
                 200                 205                 210

 Met Gln Glu Leu His Lys Ser Leu Arg Ser Leu Asn Asn Phe Cys
                 215                 220                 225

 Ser Gln Ile Gly Asp Asp Arg Pro Ile Ser Tyr Cys His Phe Ser
                 230                 235                 240

 Pro Asn Ser Lys Met Leu Ala Thr Ala Cys Trp Ser Gly Leu Cys
                 245                 250                 255

 Lys Leu Trp Ser Val Pro Asp Cys Asn Leu Leu His Thr Leu Arg
                 260                 265                 270

 Gly His Asn Thr Asn Val Gly Ala Ile Val Phe His Pro Lys Ser
                 275                 280                 285

 Thr Val Ser Leu Asp Pro Lys Asp Val Asn Leu Ala Ser Cys Ala
                 290                 295                 300

 Ala Asp Gly Ser Val Lys Leu Trp Ser Leu Asp Ser Asp Glu Pro
                 305                 310                 315

 Val Ala Asp Ile Glu Gly His Thr Val Arg Val Ala Arg Val Met
                 320                 325                 330

 Trp His Pro Ser Gly Arg Phe Leu Gly Thr Thr Cys Tyr Asp Arg
                 335                 340                 345

 Ser Trp Arg Leu Trp Asp Leu Glu Ala Gln Glu Glu Ile Leu His
                 350                 355                 360

 Gln Glu Gly His Ser Met Gly Val Tyr Asp Ile Ala Phe His Gln
                 365                 370                 375

 Asp Gly Ser Leu Ala Gly Thr Gly Gly Leu Asp Ala Phe Gly Arg
                 380                 385                 390

 Val Trp Asp Leu Arg Thr Gly Arg Cys Ile Met Phe Leu Glu Gly
                 395                 400                 405

 His Leu Lys Glu Ile Tyr Gly Ile Asn Phe Ser Pro Asn Gly Tyr
                 410                 415                 420

 His Ile Ala Thr Gly Ser Gly Asp Asn Thr Cys Lys Val Trp Asp
                 425                 430                 435

 Leu Arg Gln Arg Arg Cys Val Tyr Thr Ile Pro Ala His Gln Asn
                 440                 445                 450

 Leu Val Thr Gly Val Lys Phe Glu Pro Ile His Gly Asn Phe Leu
                 455                 460                 465

 Leu Thr Gly Ala Tyr Asp Asn Thr Ala Lys Ile Trp Thr His Pro
                 470                 475                 480

 Gly Trp Ser Pro Leu Lys Thr Leu Ala Gly His Glu Gly Lys Val
                 485                 490                 495

 Met Gly Leu Asp Ile Ser Ser Asp Gly Gln Leu Ile Ala Thr Cys
                 500                 505                 510

 Ser Tyr Asp Arg Thr Phe Lys Leu Trp Met Ala Glu
                 515                 520

<210> 1948
<211> 914
<212> DNA
<213> Homo sapien

<400> 1948
 aattagccag gcagtggtgg tgggcgcctg tagtcccagc tacttgggag 50

 gctgaggcag gagaatggtg tgaacccggg agatggcgct gcagatgagc 100

 tgagatgcac tccagcctgg gcgacaggct caaaaaagaa aaaaaaaaga 150

 acaccgatca tgtgcttctt ggatctggtg actgttctct ccctgttttc 200

 ctttcttttt gggtgtttga ggagcatggc ttagcttgag acacacacag 250

 acactgtgta cttcagtgaa gggcttaata tacagtttcc aaacctgacg 300

 actcttcttc ttgtaatggc tgcccttttc ctacctgagg ccgtcttaga 350

 gaaaggggcc agtctcctct aatgctcaga tttcccatag ttggcttttg 400

 ctgtgtctcc tgcctcaggc agtgtcattt ctgggagcag gtggttgtag 450

 tccaggcccc tccccagcag ggtctgccca ggctccttcg agcccctttc 500

 cccgcctcct ctcagcctgt ccggatgaca gtgttcgcct cctgtttaga 550

 ctgtacactc ttcaggggta ggggtgccgt cagttcttca atcagctggc 600

 acacacttgt atagtgaaat gtttacatgt gggaaaactc cgccttagac 650

 aaactaccaa agtacaatcg tgtctctctc tagccggaat gctacagaga 700

 gaaatggaac cttagatttg caacaaaagt ctgtaaactg gtctgtttgc 750

 caaagtgaac actggatgac taaggagctg aagaaggccc ccagaagcgg 800

 atttgtggtg ggttatttta ttttgcctgt ggccaatctt ctgtgaaata 850

 caatgtgctg ttggtgcaac agatgattca ataaatgtct acagcagaaa 900

 aaaaaaaaaa aggg 914

<210> 1949
<211> 80
<212> PRT
<213> Homo sapien

<400> 1949
 Met Leu Arg Phe Pro Ile Val Gly Phe Cys Cys Val Ser Cys Leu
   1               5                  10                  15

 Arg Gln Cys His Phe Trp Glu Gln Val Val Val Val Gln Ala Pro
                  20                  25                  30

 Pro Gln Gln Gly Leu Pro Arg Leu Leu Arg Ala Pro Phe Pro Ala
                  35                  40                  45

 Ser Ser Gln Pro Val Arg Met Thr Val Phe Ala Ser Cys Leu Asp
                  50                  55                  60

 Cys Thr Leu Phe Arg Gly Arg Gly Ala Val Ser Ser Ser Ile Ser
                  65                  70                  75

 Trp His Thr Leu Val
                  80

<210> 1950
<211> 2194
<212> DNA
<213> Homo sapien

<400> 1950
 cctcgtgccg agcgacccgg gcaagcgacc cgggcgcggc gcggggaggc 50

 tgaagggacg ctcgggtagg caagcgtttg cctcagcatg gagggcgggg 100

 cctcggcagc cacccccaca gcactgcctt actacgtggc cttctcccag 150

 ctgctgggcc tgaccttggt ggccatgacc ggcgcgtggc tcgggctgta 200

 ccgaggcggc attgcctggg agagcgacct gcagttcaac gcgcaccccc 250

 tctgcatggt cataggcctg atcttcctgc agggaaatgc cctgctggtt 300

 taccgtgtct tcaggaacga agctaaacgc accaccaagg tcctgcacgg 350

 gctgctgcac atctttgcgc tcgtcatcgc cctggttggc ttggtggcgg 400

 tgttcgacta ccacaggaag aagggctacg ctgacctgta cagcctacac 450

 agctggtgcg ggatccttgt ctttgtcctg tactttgtgc agtggctggt 500

 gggcttcagc ttcttcctgt tccccggagc ttcattctcc ctgcggagcc 550

 gctaccgccc acagcacatc ttctttggtg ctaccatctt cctcctttcc 600

 gtgggcaccg ccctgctggg cctgaaggag gcactgctgt tcaacctcgg 650

 gggcaagtat agcgcatttg agcccgaggg tgtcctggcc aacgtgctgg 700

 gcctgctgct ggcctgcttc ggtggggcgg tgctctacat cttgacccgg 750

 gccgactgga agcggccttc ccaggcggaa gagcaggccc tctccatgga 800

 cttcaagacg ctgacggagg gagatagccc cggctcccag tgatgcgccc 850

 ggccggccct gggggttcgc ggggtgtctt cttgcctgcc cctgctgagg 900

 cgtcttcagg actgcaggct ccggagagtg gctctggcag caggcgggcg 950

 cgtgggtgca gctgcatctg tttgagtgct gctttctggg gtcaggtctc 1000

 cgcctcctct gcttctcctt tctccgctgc tatagaccag ttcattgtgt 1050

 gtggctcccg tgtctctgtt gcccccttca gtgcagaagg ctttgggtag 1100

 gacttcgggt gttcggtcct ggtcgcagag cacagatctt taaagaagcg 1150

 agagaggagg ccccaccctc ctggcagcag atgcctgggg caaggccagg 1200

 ggaaactggg ggggcctcag ggacaggcct ggaaaggcca cgatggctgc 1250

 tgaattcaaa caaggagtcc ctccagcctg aataacacgt ggcacaaatg 1300

 ggcccggcct ttggcagagg agcaagtgat atgatgtgta aagtatgttg 1350

 gtggtgaaag caaggttccc caggagaggg gagggactgg cccctgggaa 1400

 gctctgagat gaggctgtgg cccagctgta gtcctgacct tcctcttctt 1450

 taacccttta gccctaggat ggctttggtg ggagagggga tagaagccca 1500

 tgacttcaga cagactttct cttggcagat gcaggcgggc ctcctcccag 1550

 gctgctccag acatgggggt tggggatggg gggcaccttg cagccccttc 1600

 ctgctggggc tccctccttg tagcaccccc cttgcggctc agctctggtt 1650

 tcctctccca ggctcaccca ggctctgctc aggctgggag gcagagggca 1700

 caaaccttat aattttttaa atgaaaaacc gctgctgctg gctgtggcta 1750

 gagccccctg gggctgctgg agctgctgcc tctgttctgg aggacgagcc 1800

 ttctccttat ctgctgccca tctttccagg aagtcaggat ggagtcagaa 1850

 caactacagt catcccccgt ggtgtctgca catcactcca gccccataaa 1900

 gagtgtcatg ttagctgagt caccatttgg cttcggcctg gaaatagtgt 1950

 gattagaaca ctgatcgtgt gcgaggccag gagatcaaga ccatcctgac 2000

 taacaaacac agtgaaaccc cgtctctact aaaaatacaa aaaaattagc 2050

 caggcgtggt ggtgggcgcc tgtagtccca gctacttggg aggctgaggc 2100

 aggagaatgg tgtgaacccg ggagatggcg cttgcagtga gctgagattg 2150

 cactccagcc tgggcgacag gctcaaaaaa aaaaaaaaaa aaaa 2194

<210> 1951
<211> 251
<212> PRT
<213> Homo sapien

<400> 1951
 Met Glu Gly Gly Ala Ala Ala Ala Thr Pro Thr Ala Leu Pro Tyr
   1               5                  10                  15

 Tyr Val Ala Phe Ser Gln Leu Leu Gly Leu Thr Leu Val Ala Met
                  20                  25                  30

 Thr Gly Ala Trp Leu Gly Leu Tyr Arg Gly Gly Ile Ala Trp Glu
                  35                  40                  45

 Ser Asp Leu Gln Phe Asn Ala His Pro Leu Cys Met Val Ile Gly
                  50                  55                  60

 Leu Ile Phe Leu Gln Gly Asn Ala Leu Leu Val Tyr Arg Val Phe
                  65                  70                  75

 Arg Asn Glu Ala Lys Arg Thr Thr Lys Val Leu His Gly Leu Leu
                  80                  85                  90

 His Ile Phe Ala Leu Val Ile Ala Leu Val Gly Leu Val Ala Val
                  95                 100                 105

 Phe Asp Tyr His Arg Lys Lys Gly Tyr Ala Asp Leu Tyr Ser Leu
                 110                 115                 120

 His Ser Trp Cys Gly Ile Leu Val Phe Val Leu Tyr Phe Val Gln
                 125                 130                 135

 Trp Leu Val Gly Phe Ser Phe Phe Leu Phe Pro Gly Ala Ser Phe
                 140                 145                 150

 Ser Leu Arg Ser Arg Tyr Arg Pro Gln His Ile Phe Phe Gly Ala
                 155                 160                 165

 Thr Ile Phe Leu Leu Pro Val Gly Thr Ala Leu Leu Gly Leu Lys
                 170                 175                 180

 Glu Ala Leu Leu Phe Asn Leu Gly Gly Lys Tyr Ser Ala Phe Glu
                 185                 190                 195

 Pro Glu Gly Val Leu Ala Asn Val Leu Gly Leu Leu Leu Ala Cys
                 200                 205                 210

 Phe Gly Gly Ala Val Leu Tyr Ile Leu Thr Arg Ala Asp Trp Lys
                 215                 220                 225

 Arg Pro Ser Gln Ala Glu Glu Gln Ala Leu Ser Met Asp Phe Lys
                 230                 235                 240

 Thr Leu Arg Gln Gly Asp Ser Pro Gly Ser Gln
                 245                 250

<210> 1952
<211> 10211
<212> DNA
<213> Homo sapien

<400> 1952
 gagaggtcgt tttcccgtcc ccgagagcaa gtttatttac aaatgttgga 50

 gtaataaaga aggcagaaca aaatgagctg ggctttggaa gaatggaaag 100

 aagggctgcc tacaagagct cttcagaaaa ttcaagagct tgaaggacag 150

 cttgacaaac tgaagaagga aaagcagcaa aggcagtttc agcttgacag 200

 tctcgaggct gcgcctcaga agcaaacaca gaaggttgaa aatgaaaaaa 250

 ccgagggtac aaacctgaaa agggagaatc aaagattgat ggaaatatgt 300

 gaaagtctgg agaaaactaa gcagaagatt tctcatgaac ttcaagtcaa 350

 ggagtcacaa gtgaatttcc aggaaggaca actgaattca ggcaaaaaac 400

 aaatagaaaa actggaacag gaacttaaaa ggtgtaaatc tgagcttgaa 450

 agaagccaac aagctgcgca gtctgcagat gtctctctga atccatgcaa 500

 tacaccacaa aaaattttta caactccact aacaccaagt caatattata 550

 gtggttccaa gtatgaagat ctaaaagaaa aatataataa agaggttgaa 600

 gaacgaaaaa gattagaggc agaggttaaa gccttgcagg ctaaaaaagc 650

 aagccagact cttccacaag ccaccatgaa tcaccgcgac attgcccggc 700

 atcaggcttc atcatctgtg ttctcatggc agcaagagaa gaccccaagt 750

 catctttcat ctaattctca aagaactcca attaggagag atttctctgc 800

 atcttacttt tctggggaac aagaggtgac tccaagtcga tcaactttgc 850

 aaatagggaa aagagatgct aatagcagtt tctttgacaa ttctagcagt 900

 cctcatcttt tggatcaatt aaaagcgcag aatcaagagc taagaaacaa 950

 gattaatgag ttggaactac gcctgcaagg acatgaaaaa gaaatgaaag 1000

 gccaagtgaa taagtttcaa gaactccaac tccaactgga gaaagcaaaa 1050

 gtggaattaa ttgaaaaaga gaaagttttg aacaaatgta gggatgaact 1100

 agtgagaaca acagcacaat acgaccaggc gtcaaccaag tatactgcat 1150

 tggaacaaaa actgaaaaaa ttgacggaag atttgagttg tcagcgacaa 1200

 aatgcagaaa gtgccagatg ttctctggaa cagaaaatta aggaaaaaga 1250

 aaaggagttt caagaggagc tctcccgtca acagcgttct ttccaaacac 1300

 tggaccagga gtgcatccag atgaaggcca gactcaccca ggagttacag 1350

 caagccaaga atatgcacaa cgtcctgcag gctgaactgg ataaactcac 1400

 atcagtaaag caacagctag aaaacaattt ggaagagttt aagcaaaagt 1450

 tgtgcagagc tgaacaggcg ttccaggcga gtcagatcaa ggagaatgag 1500

 ctgaggagaa gcatggagga aatgaagaag gaaaacaacc tccttaagag 1550

 tcactctgag caaaaggcca gagaagtctg ccacctggag gcagaactca 1600

 agaacatcaa acagtgttta aatcagagcc agaattttgc agaagaaatg 1650

 aaagcgaaga atacctctca ggaaaccatg ttaagagatc ttcaagaaaa 1700

 aataaatcag caagaaaact ccttgacttt agaaaaactg aagcttgctg 1750

 tggctgatct ggaaaagcag cgagattgtt ctcaagacct tttgaagaaa 1800

 agagaacatc acattgaaca acttaatgat aagttaagca agacagagaa 1850

 agagtccaaa gccttgctga gtgctttaga gttaaaaaag aaagaatatg 1900

 aattgaaaga agagaaaact ctgttttctt gttggaaaag tgaaaacgaa 1950

 aaacttttaa ctcagatgga atcagaaaag gaaaacttgc agagtaaaat 2000

 taatcacttg gaaacttgtc tgaagacaca gcaaataaaa agtcatgaat 2050

 acaacgagag agtaagaacg ctggagatgg acagagaaaa cctaagtgtc 2100

 gagatcagaa accttcacaa cgtgttagac agtaagtcag tggaggtaga 2150

 gacccagaaa ctagcttata tggagctaca gcagaaagct gagttctcag 2200

 atcagaaaca tcagaaggaa atagaaaata tgtgtttgaa gacttctcag 2250

 cttactgggc aagttgaaga tctagaacac aagcttcagt tactgtcaaa 2300

 tgaaataatg gacaaagacc ggtgttacca agacttgcat gccgaatatg 2350

 agagcctcag ggatctgcta aaatccaaag atgcttctct ggtgacaaat 2400

 gaagatcatc agagaagtct tttggctttt gatcagcagc ctgccatgca 2450

 tcattccttt gcaaatataa ttggagaaca aggaagcatg ccttcagaga 2500

 ggagtgaatg tcgtttagaa gcagaccaaa gtccgaaaaa ttctgccatc 2550

 ctacaaaata gagttgattc acttgaattt tcattagagt ctcaaaaaca 2600

 gatgaactca gacctgcaaa agcagtgtga agagttggtg caaatcaaag 2650

 gagaaataga agaaaatctc atgaaagcag aacagatgca tcaaagtttt 2700

 gtggctgaaa caagtcagcg cattagtaag ttacaggaag acacttctgc 2750

 tcaccagaat gttgttgctg aaaccttaag tgcccttgag aacaaggaaa 2800

 aagagctgca acttttaaat gataaggtag aaactgagca ggcagagatt 2850

 caagaattaa aaaagagcaa ccatctactt gaagactctc taaaggagct 2900

 acaactttta tccgaaaccc taagcttgga gaagaaagaa atgagttcca 2950

 tcatttctct aaataaaagg gaaattgaag agctgaccca agagaatggg 3000

 actcttaagg aaattaatgc atccttaaat caagagaaga tgaacttaat 3050

 ccagaaaagt gagagttttg caaactatat agatgaaagg gagaaaagca 3100

 tttcagagtt atctgatcag tacaagcaag aaaaacttat tttactacaa 3150

 agatgtgaag aaaccggaaa tgcatatgag gatcttagtc aaaaatacaa 3200

 agcagcacag gaaaagaatt ctaaattaga atgcttgcta aatgaatgca 3250

 ctagtctttg tgaaaatagg aaaaatgagt tggaacagct aaaggaagca 3300

 tttgcaaagg aacaccaaga attcttaaca aaattagcat ttgctgaaga 3350

 aagaaatcag aatctgatgc tagagttgga gacagtgcag caagctctga 3400

 gatctgagat gacagataac caaaacaatt ctaagagcga ggctggtggt 3450

 ttaaagcaag aaatcatgac tttaaaggaa gaacaaaaca aaatgcaaaa 3500

 ggaagttaat gacttattac aagagaatga acagctgatg aaggtaatga 3550

 agactaaaca tgaatgtcaa aatctagaat cagaaccaat taggaactct 3600

 gtgaaagaaa gagagagtga gagaaatcaa tgtaatttta aacctcagat 3650

 ggatcttgaa gttaaagaaa tttctctaga tagttataat gcgcagttgg 3700

 tgcaattaga agctatgcta agaaataagg aattaaaact tcaggaaagt 3750

 gagaaggaga aggagtgcct gcagcatgaa ttacagacaa ttagaggaga 3800

 tcttgaaacc agcaatttgc aagacatgca gtcacaagaa attagtggcc 3850

 ttaaagactg tgaaatagat gcggaagaaa agtatatttc agggcctcat 3900

 gagttgtcaa caagtcaaaa cgacaatgca caccttcagt gctctctgca 3950

 aacaacaatg aacaagctga atgagctaga gaaaatatgt gaaatactgc 4000

 aggctgaaaa gtatgaactc gtaactgagc tgaatgattc aaggtcagaa 4050

 tgtatcacag caactaggaa aatggcagaa gaggtaggga aactactaaa 4100

 tgaagttaaa atattaaatg atgacagtgg tcttctccat ggtgagttag 4150

 tggaagacat accaggaggt gaatttggtg aacaaccaaa tgaacagcac 4200

 cctgtgtctt tggctccatt ggacgagagt aattcctacg agcacttgac 4250

 attgtcagac aaagaagttc aaatgcactt tgccgaattg caagagaaat 4300

 tcttatcttt acaaagtgaa cacaaaattt tacatgatca gcactgtcag 4350

 atgagctcta aaatgtcaga gctgcagacc tatgttgact cattaaaggc 4400

 cgaaaatttg gtcttgtcaa cgaatctgag aaactttcaa ggtgacttgg 4450

 tgaaggagat gcagctgggc ttggaggagg ggctcgttcc atccctgtca 4500

 tcctcttgtg tgcctgacag ctctagtctt agcagtttgg gagactcctc 4550

 cttttacaga gctcttttag aacagacagg agatatgtct cttttgagta 4600

 atttagaagg ggctgtttca gcaaaccagt gcagtgtaga tgaagtattt 4650

 tgcagcagtc tgcaggagga gaatctgacc aggaaagaaa ccccttcggc 4700

 cccagcgaag ggtgttgaag agcttgagtc cctctgtgag gtgtaccggc 4750

 agtccctcga gaagctagaa gagaaaatgg aaagtcaagg gattatgaaa 4800

 aataaggaaa ttcaagagct cgagcagtta ttaagttctg aaaggcaaga 4850

 gcttgactgc cttaggaagc agtatttgtc agaaaatgaa cagtggcaac 4900

 agaagctgac aagcgtgact ctggagatgg agtccaagtt ggcggcagaa 4950

 aagaaacaga cggaacaact gtcacttgag ctggaagtag cacgactcca 5000

 gctacaaggt ctggacttaa gttctcggtc tttgcttggc atcgacacag 5050

 aagatgctat tcaaggccga aatgagagct gtgacatatc aaaagaacat 5100

 acttcagaaa ctacagaaag aacaccaaag catgatgttc atcagatttg 5150

 tgataaagat gctcagcagg acctcaatct agacattgag aaaataactg 5200

 agactggtgc attgaaaccc acaggagagt gctctgggga acagtcccca 5250

 gataccaatt atgagcctcc aggggaagat aaaacccagg gctcttcaga 5300

 atgcatttct gaattgtcat tttctggtcc taatgctttg gtacctatgg 5350

 atttcctggg gaatcaggaa gatatccata atcttcaact gcgggtaaaa 5400

 gagacatcaa atgagaattt gagattactt catgtgatag aggaccgtga 5450

 cagaaaagtt gaaagtttgc taaatgaaat gaaagaatta gactcaaaac 5500

 tccatttaca ggaggtacaa ctaatgacca aaattgaagc atgcatagaa 5550

 ttggaaaaaa tagttgggga acttaagaaa gaaaactcag atttaagtga 5600

 aaaattggaa tatttttctt gtgatcacca ggagttactc cagagagtag 5650

 aaacttctga aggcctcaat tctgatttag aaatgcatgc agataaatca 5700

 tcacgtgaag atattggaga taatgtggcc aaggtgaatg acagctggaa 5750

 ggagagattt cttgatgtgg aaaatgagct gagtaggatc agatcggaga 5800

 aagctagcat tgagcatgaa gccctctacc tggaggctga cttagaggta 5850

 gttcaaacag agaagctatg tttagaaaaa gacaatgaaa ataagcagaa 5900

 ggttattgtc tgccttgaag aagaactctc agtggtcaca agtgagagaa 5950

 accagcttcg tggagaatta gatactatgt caaaaaaaac cacggcactg 6000

 gatcagttgt ctgaaaaaat gaaggagaaa acacaagagc ttgagtctca 6050

 tcaaagtgag tgtctccatt gcattcaggt ggcagaggca gaggtgaagg 6100

 aaaagacgga actccttcag actttgtcct ctgatgtgag tgagctgtta 6150

 aaagacaaaa ctcatctcca ggaaaagctg cagagtttgg aaaaggactc 6200

 acaggcactg tctttgacaa aatgtgagct ggaaaaccaa attgcacaac 6250

 tgaataaaga gaaagaattg cttgtcaagg aatctgaaag cctgcaggcc 6300

 agactgagtg aatcagatta tgaaaagctg aatgtctcca aggccttgga 6350

 ggccgcactg gtggagaaag gtgagttcgc attgaggctg agctcaacac 6400

 aggaggaagt gcatcagctg agaagaggca tcgagaaact gagagttcgc 6450

 attgaggccg atgaaaagaa gcagctgcac atcgcagaga aactgaaaga 6500

 acgcgagcgg gagaatgatt cacttaagga taaagttgag aaccttgaaa 6550

 gggaattgca gatgtcagaa gaaaaccagg agctagtgat tcttgatgcc 6600

 gagaattcca aagcagaagt agagactcta aaaacacaaa tagaagagat 6650

 ggccagaagc ctgaaagttt ttgaattaga ccttgtcacg ttaaggtctg 6700

 aaaaagaaaa tctgacaaaa caaatacaag aaaaacaagg tcagttgtca 6750

 gaactagaca agttactctc ttcatttaaa agtctgttag aagaaaagga 6800

 gcaagcagag atacagatca aagaagaatc taaaactgca gtggagatgc 6850

 ttcagaatca gttaaaggag ctaaatgagg cagtagcagc cttgtgtggt 6900

 gaccaagaaa ttatgaaggc cacagaacag agtctagacc caccaataga 6950

 ggaagagcat cagctgagaa atagcattga aaagctgaga gcccgcctag 7000

 aagctgatga aaagaagcag ctctgtgtct tacaacaact gaaggaaagt 7050

 gagcatcatg cagatttact taagggtaga gtggagaacc ttgaaagaga 7100

 gctagagata gccaggacaa accaagagca tgcagctctt gaggcagaga 7150

 attccaaagg agaggtagag accctaaaag caaaaataga agggatgacc 7200

 caaagtctga gaggtctgga attagatgtt gttactataa ggtcagaaaa 7250

 agaaaatctg acaaatgaat tacaaaaaga gcaagagcga atatctgaat 7300

 tagaaataat aaattcatca tttgaaaata ttttgcaaga aaaagagcaa 7350

 gagaaagtac agatgaaaga aaaatcaagc actgccatgg agatgcttca 7400

 aacacaatta aaagagctca atgagagagt ggcagccctg cataatgacc 7450

 aagaagcctg taaggccaaa gagcagaatc ttagtagtca agtagagtgt 7500

 cttgaacttg agaaggctca gttgctacaa ggccttgatg aggccaaaaa 7550

 taattatatt gttttgcaat cttcagtgaa tggcctcatt caagaagtag 7600

 aagatggcaa gcagaaactg gagaagaagg atgaagaaat cagtagactg 7650

 aaaaatcaaa ttcaagacca agagcagctt gtctctaaac tgtcccaggt 7700

 ggaaggagag caccaacttt ggaaggagca aaacttagaa ctgagaaatc 7750

 tgacagtgga attggagcag aagatccaag tgctacaatc caaaaatgcc 7800

 tctttgcagg acacattaga agtgctgcag agttcttaca agaatctaga 7850

 gaatgagctt gaattgacaa aaatggacaa aatgtccttt gttgaaaaag 7900

 taaacaaaat gactgcaaag gaaactgagc tgcagaggga aatgcatgag 7950

 atggcacaga aaacagcaga gctgcaagaa gaactcagtg gagagaaaaa 8000

 taggctagct ggagagttgc agttactgtt ggaagaaata aagagcagca 8050

 aagatcaatt gaaggagctc acactagaaa atagtgaatt gaagaagagc 8100

 ctagattgca tgcacaaaga ccaggtggaa aaggaaggga aagtgagaga 8150

 ggaaatagct gaatatcagc tacggcttca tgaagctgaa aagaaacacc 8200

 aggctttgct tttggacaca aacaaacagt atgaagtaga aatccagaca 8250

 taccgagaga aattgacttc taaagaagaa tgtctcagtt cacagaagct 8300

 ggagatagac cttttaaagt ctagtaaaga agagctcaat aattcattga 8350

 aagctactac tcagattttg gaagaattga agaaaaccaa gatggacaat 8400

 ctaaaatatg taaatcagtt gaagaaggaa aatgaacgtg cccaggggaa 8450

 aatgaagttg ttgatcaaat cctgtaaaca gctggaagag gaaaaggaga 8500

 tactgcagaa agaactctct caacttcaag ctgcacagga gaagcagaaa 8550

 acaggtactg ttatggatac caaggtcgat gaattaacaa ctgagatcaa 8600

 agaactgaaa gaaactcttg aagaaaaaac caaggaggca gatgaatact 8650

 tggataagta ctgttccttg cttataagcc atgaaaagtt agagaaagct 8700

 aaagagatgt tagagacaca agtggcccat ctgtgttcac agcaatctaa 8750

 acaagattcc cgagggtctc ctttgctagg tccagttgtt ccaggaccat 8800

 ctccaatccc ttctgttact gaaaagaggt tatcatctgg ccaaaataaa 8850

 gcttcaggca agaggcaaag atccagtgga atatgggaga atggtggagg 8900

 accaacacct gctaccccag agagcttttc taaaaaaagc aagaaagcag 8950

 tcatgagtgg tattcaccct gcagaagaca cggaaggtac tgagtttgag 9000

 ccagagggac ttccagaagt tgtaaagaaa gggtttgctg acatcccgac 9050

 aggaaagact agcccatata tcctgcgaag aacaaccatg gcaactcgga 9100

 ccagcccccg cctggctgca cagaagttag cgctatcccc actgagtctc 9150

 ggcaaagaaa atcttgcaga gtcctccaaa ccaacagctg gtggcagcag 9200

 atcacaaaag gtcaaagttg ctcagcggag cccagtagat tcaggcacca 9250

 tcctccgaga acccaccacg aaatccgtcc cagtcaataa tcttcctgag 9300

 agaagtccga ctgacagccc cagagagggc ctgagggtca agcgaggccg 9350

 acttgtcccc agccccaaag ctggactgga gtccaagggc agtgagaact 9400

 gtaaggtcca gtgaaggcac tttgtgtgtc agtacccctg ggaggtgcca 9450

 gtcattgaat agataaggct gtgcctacag gacttctctt tagtcagggc 9500

 atgctttatt agtgaggaga aaacaattcc ttagaagtct taaatatatt 9550

 gtactcttta gatctcccat gtgtaggtat tgaaaaagtt tggaagcact 9600

 gatcacctgt tagcattgcc attcctctac tgcaatgtaa atagtataaa 9650

 gctatgtata taaagctttt tggtaatatg ttacaattaa aatgacaagc 9700

 actatatcac aatctctgtt tgtatgtggg ttttacacta aaaaaatgca 9750

 aaacacattt tattcttcta attaacagct cctaggaaaa tgtagacttt 9800

 tgctttatga tattctatct gtagtatgag gcatggaata gttttgtatc 9850

 gggaatttct cagagctgag taaaatgaag gaaaagcatg ttatgtgttt 9900

 ttaaggaaaa tgtgcacaca tatacatgta ggagtgttta tctttctctt 9950

 acaatctgtt ttagacatct ttgcttatga aacctgtaca tatgtgtgtg 10000

 tgggtatgtg tttatttcca gtgagggctg caggcttcct agaggtgtgc 10050

 tataccatgc gtctgtcgtt gtgctttttt ctgtttttag accaattttt 10100

 tacagttctt tggtaagcat tgtcgtatct ggtgatggat taacatatag 10150

 cctttgtttt ctaataaaat agtcgccttc gttttctgta aaaaaaaaaa 10200

 aaaaaaaaaa a 10211

<210> 1953
<211> 3113
<212> PRT
<213> Homo sapien

<400> 1953
 Met Ser Trp Ala Leu Glu Glu Trp Lys Glu Gly Leu Pro Thr Arg
   1               5                  10                  15

 Ala Leu Gln Lys Ile Gln Glu Leu Glu Gly Gln Leu Asp Lys Leu
                  20                  25                  30

 Lys Lys Glu Lys Gln Gln Arg Gln Phe Gln Leu Asp Ser Leu Glu
                  35                  40                  45

 Ala Ala Pro Gln Lys Gln Thr Gln Lys Val Glu Asn Glu Lys Thr
                  50                  55                  60

 Glu Gly Thr Asn Leu Lys Arg Glu Asn Gln Arg Leu Met Glu Ile
                  65                  70                  75

 Cys Glu Ser Leu Glu Lys Thr Lys Gln Lys Ile Ser His Glu Leu
                  80                  85                  90

 Gln Val Lys Glu Ser Gln Val Asn Phe Gln Glu Gly Gln Leu Asn
                  95                 100                 105

 Ser Gly Lys Lys Gln Ile Glu Lys Leu Glu Gln Glu Leu Lys Arg
                 110                 115                 120

 Cys Lys Ser Glu Leu Glu Arg Ser Gln Gln Ala Ala Gln Ser Ala
                 125                 130                 135

 Asp Val Ser Leu Asn Pro Cys Asn Thr Pro Gln Lys Ile Phe Thr
                 140                 145                 150

 Thr Pro Leu Thr Pro Ser Gln Tyr Tyr Ser Gly Ser Lys Tyr Glu
                 155                 160                 165

 Asp Leu Lys Glu Lys Tyr Asn Lys Glu Val Glu Glu Arg Lys Arg
                 170                 175                 180

 Leu Glu Ala Glu Val Lys Ala Leu Gln Ala Lys Lys Ala Ser Gln
                 185                 190                 195

 Thr Leu Pro Gln Ala Thr Met Asn His Arg Asp Ile Ala Arg His
                 200                 205                 210

 Gln Ala Ser Ser Ser Val Phe Ser Trp Gln Gln Glu Lys Thr Pro
                 215                 220                 225

 Ser His Leu Ser Ser Asn Ser Gln Arg Thr Pro Ile Arg Arg Asp
                 230                 235                 240

 Phe Ser Ala Ser Tyr Phe Ser Gly Glu Gln Glu Val Thr Pro Ser
                 245                 250                 255

 Arg Ser Thr Leu Gln Ile Gly Lys Arg Asp Ala Asn Ser Ser Phe
                 260                 265                 270

 Phe Asp Asn Ser Ser Ser Pro His Leu Leu Asp Gln Leu Lys Ala
                 275                 280                 285

 Gln Asn Gln Glu Leu Arg Asn Lys Ile Asn Glu Leu Glu Leu Arg
                 290                 295                 300

 Leu Gln Gly His Glu Lys Glu Met Lys Gly Gln Val Asn Lys Phe
                 305                 310                 315

 Gln Glu Leu Gln Leu Gln Leu Glu Lys Ala Lys Val Glu Leu Ile
                 320                 325                 330

 Glu Lys Glu Lys Val Leu Asn Lys Cys Arg Asp Glu Leu Val Arg
                 335                 340                 345

 Thr Thr Ala Gln Tyr Asp Gln Ala Ser Thr Lys Tyr Thr Ala Leu
                 350                 355                 360

 Glu Gln Lys Leu Lys Lys Leu Thr Glu Asp Leu Ser Cys Gln Arg
                 365                 370                 375

 Gln Asn Ala Glu Ser Ala Arg Cys Ser Leu Glu Gln Lys Ile Lys
                 380                 385                 390

 Glu Lys Glu Lys Glu Phe Gln Glu Glu Leu Ser Arg Gln Gln Arg
                 395                 400                 405

 Ser Phe Gln Thr Leu Asp Gln Glu Cys Ile Gln Met Lys Ala Arg
                 410                 415                 420

 Leu Thr Gln Glu Leu Gln Gln Ala Lys Asn Met His Asn Val Leu
                 425                 430                 435

 Gln Ala Glu Leu Asp Lys Leu Thr Ser Val Lys Gln Gln Leu Glu
                 440                 445                 450

 Asn Asn Leu Glu Glu Phe Lys Gln Lys Leu Cys Arg Ala Glu Gln
                 455                 460                 465

 Ala Phe Gln Ala Ser Gln Ile Lys Glu Asn Glu Leu Arg Arg Ser
                 470                 475                 480

 Met Glu Glu Met Lys Lys Glu Asn Asn Leu Leu Lys Ser His Ser
                 485                 490                 495

 Glu Gln Lys Ala Arg Glu Val Cys His Leu Glu Ala Glu Leu Lys
                 500                 505                 510

 Asn Ile Lys Gln Cys Leu Asn Gln Ser Gln Asn Phe Ala Glu Glu
                 515                 520                 525

 Met Lys Ala Lys Asn Thr Ser Gln Glu Thr Met Leu Arg Asp Leu
                 530                 535                 540

 Gln Glu Lys Ile Asn Gln Gln Glu Asn Ser Leu Thr Leu Glu Lys
                 545                 550                 555

 Leu Lys Leu Ala Val Ala Asp Leu Glu Lys Gln Arg Asp Cys Ser
                 560                 565                 570

 Gln Asp Leu Leu Lys Lys Arg Glu His His Ile Glu Gln Leu Asn
                 575                 580                 585

 Asp Lys Leu Ser Lys Thr Glu Lys Glu Ser Lys Ala Leu Leu Ser
                 590                 595                 600

 Ala Leu Glu Leu Lys Lys Lys Glu Tyr Glu Leu Lys Glu Glu Lys
                 605                 610                 615

 Thr Leu Phe Ser Cys Trp Lys Ser Glu Asn Glu Lys Leu Leu Thr
                 620                 625                 630

 Gln Met Glu Ser Glu Lys Glu Asn Leu Gln Ser Lys Ile Asn His
                 635                 640                 645

 Leu Glu Thr Cys Leu Lys Thr Gln Gln Ile Lys Ser His Glu Tyr
                 650                 655                 660

 Asn Glu Arg Val Arg Thr Leu Glu Met Asp Arg Glu Asn Leu Ser
                 665                 670                 675

 Val Glu Ile Arg Asn Leu His Asn Val Leu Asp Ser Lys Ser Val
                 680                 685                 690

 Glu Val Glu Thr Gln Lys Leu Ala Tyr Met Glu Leu Gln Gln Lys
                 695                 700                 705

 Ala Glu Phe Ser Asp Gln Lys His Gln Lys Glu Ile Glu Asn Met
                 710                 715                 720

 Cys Leu Lys Thr Ser Gln Leu Thr Gly Gln Val Glu Asp Leu Glu
                 725                 730                 735

 His Lys Leu Gln Leu Leu Ser Asn Glu Ile Met Asp Lys Asp Arg
                 740                 745                 750

 Cys Tyr Gln Asp Leu His Ala Glu Tyr Glu Ser Leu Arg Asp Leu
                 755                 760                 765

 Leu Lys Ser Lys Asp Ala Ser Leu Val Thr Asn Glu Asp His Gln
                 770                 775                 780

 Arg Ser Leu Leu Ala Phe Asp Gln Gln Pro Ala Met His His Ser
                 785                 790                 795

 Phe Ala Asn Ile Ile Gly Glu Gln Gly Ser Met Pro Ser Glu Arg
                 800                 805                 810

 Ser Glu Cys Arg Leu Glu Ala Asp Gln Ser Pro Lys Asn Ser Ala
                 815                 820                 825

 Ile Leu Gln Asn Arg Val Asp Ser Leu Glu Phe Ser Leu Glu Ser
                 830                 835                 840

 Gln Lys Gln Met Asn Ser Asp Leu Gln Lys Gln Cys Glu Glu Leu
                 845                 850                 855

 Val Gln Ile Lys Gly Glu Ile Glu Glu Asn Leu Met Lys Ala Glu
                 860                 865                 870

 Gln Met His Gln Ser Phe Val Ala Glu Thr Ser Gln Arg Ile Ser
                 875                 880                 885

 Lys Leu Gln Glu Asp Thr Ser Ala His Gln Asn Val Val Ala Glu
                 890                 895                 900

 Thr Leu Ser Ala Leu Glu Asn Lys Glu Lys Glu Leu Gln Leu Leu
                 905                 910                 915

 Asn Asp Lys Val Glu Thr Glu Gln Ala Glu Ile Gln Glu Leu Lys
                 920                 925                 930

 Lys Ser Asn His Leu Leu Glu Asp Ser Leu Lys Glu Leu Gln Leu
                 935                 940                 945

 Leu Ser Glu Thr Leu Ser Leu Glu Lys Lys Glu Met Ser Ser Ile
                 950                 955                 960

 Ile Ser Leu Asn Lys Arg Glu Ile Glu Glu Leu Thr Gln Glu Asn
                 965                 970                 975

 Gly Thr Leu Lys Glu Ile Asn Ala Ser Leu Asn Gln Glu Lys Met
                 980                 985                 990

 Asn Leu Ile Gln Lys Ser Glu Ser Phe Ala Asn Tyr Ile Asp Glu
                 995                1000                1005

 Arg Glu Lys Ser Ile Ser Glu Leu Ser Asp Gln Tyr Lys Gln Glu
                1010                1015                1020

 Lys Leu Ile Leu Leu Gln Arg Cys Glu Glu Thr Gly Asn Ala Tyr
                1025                1030                1035

 Glu Asp Leu Ser Gln Lys Tyr Lys Ala Ala Gln Glu Lys Asn Ser
                1040                1045                1050

 Lys Leu Glu Cys Leu Leu Asn Glu Cys Thr Ser Leu Cys Glu Asn
                1055                1060                1065

 Arg Lys Asn Glu Leu Glu Gln Leu Lys Glu Ala Phe Ala Lys Glu
                1070                1075                1080

 His Gln Glu Phe Leu Thr Lys Leu Ala Phe Ala Glu Glu Arg Asn
                1085                1090                1095

 Gln Asn Leu Met Leu Glu Leu Glu Thr Val Gln Gln Ala Leu Arg
                1100                1105                1110

 Ser Glu Met Thr Asp Asn Gln Asn Asn Ser Lys Ser Glu Ala Gly
                1115                1120                1125

 Gly Leu Lys Gln Glu Ile Met Thr Leu Lys Glu Glu Gln Asn Lys
                1130                1135                1140

 Met Gln Lys Glu Val Asn Asp Leu Leu Gln Glu Asn Glu Gln Leu
                1145                1150                1155

 Met Lys Val Met Lys Thr Lys His Glu Cys Gln Asn Leu Glu Ser
                1160                1165                1170

 Glu Pro Ile Arg Asn Ser Val Lys Glu Arg Glu Ser Glu Arg Asn
                1175                1180                1185

 Gln Cys Asn Phe Lys Pro Gln Met Asp Leu Glu Val Lys Glu Ile
                1190                1195                1200

 Ser Leu Asp Ser Tyr Asn Ala Gln Leu Val Gln Leu Glu Ala Met
                1205                1210                1215

 Leu Arg Asn Lys Glu Leu Lys Leu Gln Glu Ser Glu Lys Glu Lys
                1220                1225                1230

 Glu Cys Leu Gln His Glu Leu Gln Thr Ile Arg Gly Asp Leu Glu
                1235                1240                1245

 Thr Ser Asn Leu Gln Asp Met Gln Ser Gln Glu Ile Ser Gly Leu
                1250                1255                1260

 Lys Asp Cys Glu Ile Asp Ala Glu Glu Lys Tyr Ile Ser Gly Pro
                1265                1270                1275

 His Glu Leu Ser Thr Ser Gln Asn Asp Asn Ala His Leu Gln Cys
                1280                1285                1290

 Ser Leu Gln Thr Thr Met Asn Lys Leu Asn Glu Leu Glu Lys Ile
                1295                1300                1305

 Cys Glu Ile Leu Gln Ala Glu Lys Tyr Glu Leu Val Thr Glu Leu
                1310                1315                1320

 Asn Asp Ser Arg Ser Glu Cys Ile Thr Ala Thr Arg Lys Met Ala
                1325                1330                1335

 Glu Glu Val Gly Lys Leu Leu Asn Glu Val Lys Ile Leu Asn Asp
                1340                1345                1350

 Asp Ser Gly Leu Leu His Gly Glu Leu Val Glu Asp Ile Pro Gly
                1355                1360                1365

 Gly Glu Phe Gly Glu Gln Pro Asn Glu Gln His Pro Val Ser Leu
                1370                1375                1380

 Ala Pro Leu Asp Glu Ser Asn Ser Tyr Glu His Leu Thr Leu Ser
                1385                1390                1395

 Asp Lys Glu Val Gln Met His Phe Ala Glu Leu Gln Glu Lys Phe
                1400                1405                1410

 Leu Ser Leu Gln Ser Glu His Lys Ile Leu His Asp Gln His Cys
                1415                1420                1425

 Gln Met Ser Ser Lys Met Ser Glu Leu Gln Thr Tyr Val Asp Ser
                1430                1435                1440

 Leu Lys Ala Glu Asn Leu Val Leu Ser Thr Asn Leu Arg Asn Phe
                1445                1450                1455

 Gln Gly Asp Leu Val Lys Glu Met Gln Leu Gly Leu Glu Glu Gly
                1460                1465                1470

 Leu Val Pro Ser Leu Ser Ser Ser Cys Val Pro Asp Ser Ser Ser
                1475                1480                1485

 Leu Ser Ser Leu Gly Asp Ser Ser Phe Tyr Arg Ala Leu Leu Glu
                1490                1495                1500

 Gln Thr Gly Asp Met Ser Leu Leu Ser Asn Leu Glu Gly Ala Val
                1505                1510                1515

 Ser Ala Asn Gln Cys Ser Val Asp Glu Val Phe Cys Ser Ser Leu
                1520                1525                1530

 Gln Glu Glu Asn Leu Thr Arg Lys Glu Thr Pro Ser Ala Pro Ala
                1535                1540                1545

 Lys Gly Val Glu Glu Leu Glu Ser Leu Cys Glu Val Tyr Arg Gln
                1550                1555                1560

 Ser Leu Glu Lys Leu Glu Glu Lys Met Glu Ser Gln Gly Ile Met
                1565                1570                1575

 Lys Asn Lys Glu Ile Gln Glu Leu Glu Gln Leu Leu Ser Ser Glu
                1580                1585                1590

 Arg Gln Glu Leu Asp Cys Leu Arg Lys Gln Tyr Leu Ser Glu Asn
                1595                1600                1605

 Glu Gln Trp Gln Gln Lys Leu Thr Ser Val Thr Leu Glu Met Glu
                1610                1615                1620

 Ser Lys Leu Ala Ala Glu Lys Lys Gln Thr Glu Gln Leu Ser Leu
                1625                1630                1635

 Glu Leu Glu Val Ala Arg Leu Gln Leu Gln Gly Leu Asp Leu Ser
                1640                1645                1650

 Ser Arg Ser Leu Leu Gly Ile Asp Thr Glu Asp Ala Ile Gln Gly
                1655                1660                1665

 Arg Asn Glu Ser Cys Asp Ile Ser Lys Glu His Thr Ser Glu Thr
                1670                1675                1680

 Thr Glu Arg Thr Pro Lys His Asp Val His Gln Ile Cys Asp Lys
                1685                1690                1695

 Asp Ala Gln Gln Asp Leu Asn Leu Asp Ile Glu Lys Ile Thr Glu
                1700                1705                1710

 Thr Gly Ala Leu Lys Pro Thr Gly Glu Cys Ser Gly Glu Gln Ser
                1715                1720                1725

 Pro Asp Thr Asn Tyr Glu Pro Pro Gly Glu Asp Lys Thr Gln Gly
                1730                1735                1740

 Ser Ser Glu Cys Ile Ser Glu Leu Ser Phe Ser Gly Pro Asn Ala
                1745                1750                1755

 Leu Val Pro Met Asp Phe Leu Gly Asn Gln Glu Asp Ile His Asn
                1760                1765                1770

 Leu Gln Leu Arg Val Lys Glu Thr Ser Asn Glu Asn Leu Arg Leu
                1775                1780                1785

 Leu His Val Ile Glu Asp Arg Asp Arg Lys Val Glu Ser Leu Leu
                1790                1795                1800

 Asn Glu Met Lys Glu Leu Asp Ser Lys Leu His Leu Gln Glu Val
                1805                1810                1815

 Gln Leu Met Thr Lys Ile Glu Ala Cys Ile Glu Leu Glu Lys Ile
                1820                1825                1830

 Val Gly Glu Leu Lys Lys Glu Asn Ser Asp Leu Ser Glu Lys Leu
                1835                1840                1845

 Glu Tyr Phe Ser Cys Asp His Gln Glu Leu Leu Gln Arg Val Glu
                1850                1855                1860

 Thr Ser Glu Gly Leu Asn Ser Asp Leu Glu Met His Ala Asp Lys
                1865                1870                1875

 Ser Ser Arg Glu Asp Ile Gly Asp Asn Val Ala Lys Val Asn Asp
                1880                1885                1890

 Ser Trp Lys Glu Arg Phe Leu Asp Val Glu Asn Glu Leu Ser Arg
                1895                1900                1905

 Ile Arg Ser Glu Lys Ala Ser Ile Glu His Glu Ala Leu Tyr Leu
                1910                1915                1920

 Glu Ala Asp Leu Glu Val Val Gln Thr Glu Lys Leu Cys Leu Glu
                1925                1930                1935

 Lys Asp Asn Glu Asn Lys Gln Lys Val Ile Val Cys Leu Glu Glu
                1940                1945                1950

 Glu Leu Ser Val Val Thr Ser Glu Arg Asn Gln Leu Arg Gly Glu
                1955                1960                1965

 Leu Asp Thr Met Ser Lys Lys Thr Thr Ala Leu Asp Gln Leu Ser
                1970                1975                1980

 Glu Lys Met Lys Glu Lys Thr Gln Glu Leu Glu Ser His Gln Ser
                1985                1990                1995

 Glu Cys Leu His Cys Ile Gln Val Ala Glu Ala Glu Val Lys Glu
                2000                2005                2010

 Lys Thr Glu Leu Leu Gln Thr Leu Ser Ser Asp Val Ser Glu Leu
                2015                2020                2025

 Leu Lys Asp Lys Thr His Leu Gln Glu Lys Leu Gln Ser Leu Glu
                2030                2035                2040

 Lys Asp Ser Gln Ala Leu Ser Leu Thr Lys Cys Glu Leu Glu Asn
                2045                2050                2055

 Gln Ile Ala Gln Leu Asn Lys Glu Lys Glu Leu Leu Val Lys Glu
                2060                2065                2070

 Ser Glu Ser Leu Gln Ala Arg Leu Ser Glu Ser Asp Tyr Glu Lys
                2075                2080                2085

 Leu Asn Val Ser Lys Ala Leu Glu Ala Ala Leu Val Glu Lys Gly
                2090                2095                2100

 Glu Phe Ala Leu Arg Leu Ser Ser Thr Gln Glu Glu Val His Gln
                2105                2110                2115

 Leu Arg Arg Gly Ile Glu Lys Leu Arg Val Arg Ile Glu Ala Asp
                2120                2125                2130

 Glu Lys Lys Gln Leu His Ile Ala Glu Lys Leu Lys Glu Arg Glu
                2135                2140                2145

 Arg Glu Asn Asp Ser Leu Lys Asp Lys Val Glu Asn Leu Glu Arg
                2150                2155                2160

 Glu Leu Gln Met Ser Glu Glu Asn Gln Glu Leu Val Ile Leu Asp
                2165                2170                2175

 Ala Glu Asn Ser Lys Ala Glu Val Glu Thr Leu Lys Thr Gln Ile
                2180                2185                2190

 Glu Glu Met Ala Arg Ser Leu Lys Val Phe Glu Leu Asp Leu Val
                2195                2200                2205

 Thr Leu Arg Ser Glu Lys Glu Asn Leu Thr Lys Gln Ile Gln Glu
                2210                2215                2220

 Lys Gln Gly Gln Leu Ser Glu Leu Asp Lys Leu Leu Ser Ser Phe
                2225                2230                2235

 Lys Ser Leu Leu Glu Glu Lys Glu Gln Ala Glu Ile Gln Ile Lys
                2240                2245                2250

 Glu Glu Ser Lys Thr Ala Val Glu Met Leu Gln Asn Gln Leu Lys
                2255                2260                2265

 Glu Leu Asn Glu Ala Val Ala Ala Leu Cys Gly Asp Gln Glu Ile
                2270                2275                2280

 Met Lys Ala Thr Glu Gln Ser Leu Asp Pro Pro Ile Glu Glu Glu
                2285                2290                2295

 His Gln Leu Arg Asn Ser Ile Glu Lys Leu Arg Ala Arg Leu Glu
                2300                2305                2310

 Ala Asp Glu Lys Lys Gln Leu Cys Val Leu Gln Gln Leu Lys Glu
                2315                2320                2325

 Ser Glu His His Ala Asp Leu Leu Lys Gly Arg Val Glu Asn Leu
                2330                2335                2340

 Glu Arg Glu Leu Glu Ile Ala Arg Thr Asn Gln Glu His Ala Ala
                2345                2350                2355

 Leu Glu Ala Glu Asn Ser Lys Gly Glu Val Glu Thr Leu Lys Ala
                2360                2365                2370

 Lys Ile Glu Gly Met Thr Gln Ser Leu Arg Gly Leu Glu Leu Asp
                2375                2380                2385

 Val Val Thr Ile Arg Ser Glu Lys Glu Asn Leu Thr Asn Glu Leu
                2390                2395                2400

 Gln Lys Glu Gln Glu Arg Ile Ser Glu Leu Glu Ile Ile Asn Ser
                2405                2410                2415

 Ser Phe Glu Asn Ile Leu Gln Glu Lys Glu Gln Glu Lys Val Gln
                2420                2425                2430

 Met Lys Glu Lys Ser Ser Thr Ala Met Glu Met Leu Gln Thr Gln
                2435                2440                2445

 Leu Lys Glu Leu Asn Glu Arg Val Ala Ala Leu His Asn Asp Gln
                2450                2455                2460

 Glu Ala Cys Lys Ala Lys Glu Gln Asn Leu Ser Ser Gln Val Glu
                2465                2470                2475

 Cys Leu Glu Leu Glu Lys Ala Gln Leu Leu Gln Gly Leu Asp Glu
                2480                2485                2490

 Ala Lys Asn Asn Tyr Ile Val Leu Gln Ser Ser Val Asn Gly Leu
                2495                2500                2505

 Ile Gln Glu Val Glu Asp Gly Lys Gln Lys Leu Glu Lys Lys Asp
                2510                2515                2520

 Glu Glu Ile Ser Arg Leu Lys Asn Gln Ile Gln Asp Gln Glu Gln
                2525                2530                2535

 Leu Val Ser Lys Leu Ser Gln Val Glu Gly Glu His Gln Leu Trp
                2540                2545                2550

 Lys Glu Gln Asn Leu Glu Leu Arg Asn Leu Thr Val Glu Leu Glu
                2555                2560                2565

 Gln Lys Ile Gln Val Leu Gln Ser Lys Asn Ala Ser Leu Gln Asp
                2570                2575                2580

 Thr Leu Glu Val Leu Gln Ser Ser Tyr Lys Asn Leu Glu Asn Glu
                2585                2590                2595

 Leu Glu Leu Thr Lys Met Asp Lys Met Ser Phe Val Glu Lys Val
                2600                2605                2610

 Asn Lys Met Thr Ala Lys Glu Thr Glu Leu Gln Arg Glu Met His
                2615                2620                2625

 Glu Met Ala Gln Lys Thr Ala Glu Leu Gln Glu Glu Leu Ser Gly
                2630                2635                2640

 Glu Lys Asn Arg Leu Ala Gly Glu Leu Gln Leu Leu Leu Glu Glu
                2645                2650                2655

 Ile Lys Ser Ser Lys Asp Gln Leu Lys Glu Leu Thr Leu Glu Asn
                2660                2665                2670

 Ser Glu Leu Lys Lys Ser Leu Asp Cys Met His Lys Asp Gln Val
                2675                2680                2685

 Glu Lys Glu Gly Lys Val Arg Glu Glu Ile Ala Glu Tyr Gln Leu
                2690                2695                2700

 Arg Leu His Glu Ala Glu Lys Lys His Gln Ala Leu Leu Leu Asp
                2705                2710                2715

 Thr Asn Lys Gln Tyr Glu Val Glu Ile Gln Thr Tyr Arg Glu Lys
                2720                2725                2730

 Leu Thr Ser Lys Glu Glu Cys Leu Ser Ser Gln Lys Leu Glu Ile
                2735                2740                2745

 Asp Leu Leu Lys Ser Ser Lys Glu Glu Leu Asn Asn Ser Leu Lys
                2750                2755                2760

 Ala Thr Thr Gln Ile Leu Glu Glu Leu Lys Lys Thr Lys Met Asp
                2765                2770                2775

 Asn Leu Lys Tyr Val Asn Gln Leu Lys Lys Glu Asn Glu Arg Ala
                2780                2785                2790

 Gln Gly Lys Met Lys Leu Leu Ile Lys Ser Cys Lys Gln Leu Glu
                2795                2800                2805

 Glu Glu Lys Glu Ile Leu Gln Lys Glu Leu Ser Gln Leu Gln Ala
                2810                2815                2820

 Ala Gln Glu Lys Gln Lys Thr Gly Thr Val Met Asp Thr Lys Val
                2825                2830                2835

 Asp Glu Leu Thr Thr Glu Ile Lys Glu Leu Lys Glu Thr Leu Glu
                2840                2845                2850

 Glu Lys Thr Lys Glu Ala Asp Glu Tyr Leu Asp Lys Tyr Cys Ser
                2855                2860                2865

 Leu Leu Ile Ser His Glu Lys Leu Glu Lys Ala Lys Glu Met Leu
                2870                2875                2880

 Glu Thr Gln Val Ala His Leu Cys Ser Gln Gln Ser Lys Gln Asp
                2885                2890                2895

 Ser Arg Gly Ser Pro Leu Leu Gly Pro Val Val Pro Gly Pro Ser
                2900                2905                2910

 Pro Ile Pro Ser Val Thr Glu Lys Arg Leu Ser Ser Gly Gln Asn
                2915                2920                2925

 Lys Ala Ser Gly Lys Arg Gln Arg Ser Ser Gly Ile Trp Glu Asn
                2930                2935                2940

 Gly Gly Gly Pro Thr Pro Ala Thr Pro Glu Ser Phe Ser Lys Lys
                2945                2950                2955

 Ser Lys Lys Ala Val Met Ser Gly Ile His Pro Ala Glu Asp Thr
                2960                2965                2970

 Glu Gly Thr Glu Phe Glu Pro Glu Gly Leu Pro Glu Val Val Lys
                2975                2980                2985

 Lys Gly Phe Ala Asp Ile Pro Thr Gly Lys Thr Ser Pro Tyr Ile
                2990                2995                3000

 Leu Arg Arg Thr Thr Met Ala Thr Arg Thr Ser Pro Arg Leu Ala
                3005                3010                3015

 Ala Gln Lys Leu Ala Leu Ser Pro Leu Ser Leu Gly Lys Glu Asn
                3020                3025                3030

 Leu Ala Glu Ser Ser Lys Pro Thr Ala Gly Gly Ser Arg Ser Gln
                3035                3040                3045

 Lys Val Lys Val Ala Gln Arg Ser Pro Val Asp Ser Gly Thr Ile
                3050                3055                3060

 Leu Arg Glu Pro Thr Thr Lys Ser Val Pro Val Asn Asn Leu Pro
                3065                3070                3075

 Glu Arg Ser Pro Thr Asp Ser Pro Arg Glu Gly Leu Arg Val Lys
                3080                3085                3090

 Arg Gly Arg Leu Val Pro Ser Pro Lys Ala Gly Leu Glu Ser Lys
                3095                3100                3105

 Gly Ser Glu Asn Cys Lys Val Gln
                3110

<210> 1954
<211> 1526
<212> DNA
<213> Homo sapien

<400> 1954
 gcatctgcgc aggcgcccgg ctcctaagtc tacccaggaa ctgaccctgc 50

 tctctccttt ccctgttaga catgggcact ccacagaagg atgttattat 100

 caagtcagat gcaccggaca ctttgttatt ggagaaacat gcagattata 150

 tcgcatccta tggctcaaag aaagatgatt atgaatactg tatgtctgag 200

 tatttgagaa tgagtggcat ctattggggt ctgacagtaa tggatctcat 250

 gggacaactt catcgcatga atagagaaga gattctggca tttattaagt 300

 cttgccaaca tgaatgtggt ggaataagtg ctagtatcgg acatgatcct 350

 catcttttat acactcttag tgctgtccag attcttacgc tgtatgacag 400

 tattaatgtt attgacgtaa ataaagttgt ggaatatgtt aaaggtctac 450

 agaaagaaga tggttctttt gctggagata tttggggaga aattgacaca 500

 agattctctt tttgtgcggt ggcaactttg gctttgttgg ggaagcttga 550

 tgctattaat gtggaaaagg caatcgaatt tgttttatcc tgtatgaact 600

 ttgacggtgg atttggttgc agaccaggtt ctgaatccca tgctgggcag 650

 atctattgtt gcacaggatt tctggctatt acaagtcagt tgcatcaagt 700

 aaattctgat ttacttggct ggtggctttg tgaacgacaa ttaccctcag 750

 gcgggctcaa tggaaggccg gagaagttac cagatgtatg ctactcatgg 800

 tgggtcctgg cttccctaaa gataattgga agacttcatt ggattgatag 850

 agagaaactg cgtaatttca ttttagcatg tcaagatgaa gaaacggggg 900

 gatttgcaga caggccagga gatatggtgg atccttttca taccttattt 950

 ggaattgctg gattgtcact tttgggagaa gaacagatta aacctgttaa 1000

 tcctgtcttt tgcatgcctg aagaagtgct tcagagagtg aatgttcagc 1050

 ctgagctagt gagctagatt cattgaattg aaagttgcat agtatagttt 1100

 tgccatttta acatttctgt atttgaagtg cttatcgaat ctaaaagtga 1150

 ctactgttaa tattttgtat attgtgttaa attaatttta ataaattata 1200

 taattataca tattgtaaaa taaagaccgg tattttattt tctgcttttt 1250

 attctgaagt cctgttattc tgactacagt tctttgtgta tacttctgtg 1300

 tctgttatgt tcaataactg agctaacata aaataactct aggtttctac 1350

 ttgatttttc ccccatgtat acctttcatc tgttctatag caagttgatg 1400

 taaattggtt tgtcaacaag aatgttaact gatgaaagtg gatagaaccc 1450

 atacatgaat taaatgatgc acaaaataaa tggctgttga aatttgaaaa 1500

 aaaaaaaaaa aaaaaaaaaa aaaaaa 1526

<210> 1955
<211> 331
<212> PRT
<213> Homo sapien

<400> 1955
 Met Gly Thr Pro Gln Lys Asp Val Ile Ile Lys Ser Asp Ala Pro
   1               5                  10                  15

 Asp Thr Leu Leu Leu Glu Lys His Ala Asp Tyr Ile Ala Ser Tyr
                  20                  25                  30

 Gly Ser Lys Lys Asp Asp Tyr Glu Tyr Cys Met Ser Glu Tyr Leu
                  35                  40                  45

 Arg Met Ser Gly Ile Tyr Trp Gly Leu Thr Val Met Asp Leu Met
                  50                  55                  60

 Gly Gln Leu His Arg Met Asn Arg Glu Glu Ile Leu Ala Phe Ile
                  65                  70                  75

 Lys Ser Cys Gln His Glu Cys Gly Gly Ile Ser Ala Ser Ile Gly
                  80                  85                  90

 His Asp Pro His Leu Leu Tyr Thr Leu Ser Ala Val Gln Ile Leu
                  95                 100                 105

 Thr Leu Tyr Asp Ser Ile Asn Val Ile Asp Val Asn Lys Val Val
                 110                 115                 120

 Glu Tyr Val Lys Gly Leu Gln Lys Glu Asp Gly Ser Phe Ala Gly
                 125                 130                 135

 Asp Ile Trp Gly Glu Ile Asp Thr Arg Phe Ser Phe Cys Ala Val
                 140                 145                 150

 Ala Thr Leu Ala Leu Leu Gly Lys Leu Asp Ala Ile Asn Val Glu
                 155                 160                 165

 Lys Ala Ile Glu Phe Val Leu Ser Cys Met Asn Phe Asp Gly Gly
                 170                 175                 180

 Phe Gly Cys Arg Pro Gly Ser Glu Ser His Ala Gly Gln Ile Tyr
                 185                 190                 195

 Cys Cys Thr Gly Phe Leu Ala Ile Thr Ser Gln Leu His Gln Val
                 200                 205                 210

 Asn Ser Asp Leu Leu Gly Trp Trp Leu Cys Glu Arg Gln Leu Pro
                 215                 220                 225

 Ser Gly Gly Leu Asn Gly Arg Pro Glu Lys Leu Pro Asp Val Cys
                 230                 235                 240

 Tyr Ser Trp Trp Val Leu Ala Ser Leu Lys Ile Ile Gly Arg Leu
                 245                 250                 255

 His Trp Ile Asp Arg Glu Lys Leu Arg Asn Phe Ile Leu Ala Cys
                 260                 265                 270

 Gln Asp Glu Glu Thr Gly Gly Phe Ala Asp Arg Pro Gly Asp Met
                 275                 280                 285

 Val Asp Pro Phe His Thr Leu Phe Gly Ile Ala Gly Leu Ser Leu
                 290                 295                 300

 Leu Gly Glu Glu Gln Ile Lys Pro Val Asn Pro Val Phe Cys Met
                 305                 310                 315

 Pro Glu Glu Val Leu Gln Arg Val Asn Val Gln Pro Glu Leu Val
                 320                 325                 330

 Ser


<210> 1956
<211> 4205
<212> DNA
<213> Homo sapien

<400> 1956
 gggtgattca gcgcccggcg aggcggaagc ggccgcaaga ggaggagggg 50

 agagcccgtc cgcgcctggg ctcccggggt ggcacgagcc cgcggccgga 100

 gtgcgaggcg gaggcgagga ggccgcgggg acgggaggcg aggccggccg 150

 ggcccccgaa gccatggaga acgcgcacac caagacggtg gaggaggtgc 200

 tgggccactt cggcgtcaac gagagtacgg ggctgagcct ggaacaggtc 250

 aagaagctta aggagagatg gggctccaac gagttaccgg ctgaagaagg 300

 aaaaaccttg ctggaacttg tgattgagca gtttgaagac ttgctagtta 350

 ggattttatt actggcagca tgtatatctt ttgttttggc ttggtttgaa 400

 gaaggtgaag aaacaattac agcctttgta gaaccttttg taattttact 450

 catattagta gccaatgcaa ttgtgggtgt atggcaggaa agaaatgctg 500

 aaaatgccat cgaagccctt aaggaatatg agcctgaaat gggcaaagtg 550

 tatcgacagg acagaaagag tgtgcagcgg attaaagcta aagacatagt 600

 tcctggtgat attgtagaaa ttgctgttgg tgacaaagtt cctgctgata 650

 taaggttaac ttccatcaaa tctaccacac taagagttga ccagtcaatt 700

 ctcacaggtg aatctgtctc tgtcatcaag cacactgatc ccgtccctga 750

 cccacgagct gtcaaccaag ataaaaagaa catgctgttt tctggtacaa 800

 acattgctgc tgggaaagct atgggagtgg tggtagcaac tggagttaac 850

 accgaaattg gcaagatccg ggatgaaatg gtggcaacag aacaggagag 900

 aacacccctt cagcaaaaac tagatgaatt tggggaacag ctttccaaag 950

 tcatctccct tatttgcatt gcagtctgga tcataaatat tgggcacttc 1000

 aatgacccgg ttcatggagg gtcctggatc agaggtgcta tttactactt 1050

 taaaattgca gtggccctgg ctgtagcagc cattcctgaa ggtctgcctg 1100

 cagtcatcac cacctgcctg gctcttggaa ctcgcagaat ggcaaagaaa 1150

 aatgccattg ttcgaagcct cccgtctgtg gaaacccttg gttgtacttc 1200

 tgttatctgc tcagacaaga ctggtacact tacaacaaac cagatgtcag 1250

 tctgcaggat gttcattctg gacagagtgg aaggtgatac ttgttccctt 1300

 aatgagttta ccataactgg atcaacttat gcacctattg gagaagtgca 1350

 taaagatgat aaaccagtga attgtcacca gtatgatggt ctggtagaat 1400

 tagcaacaat ttgtgctctt tgtaatgact ctgctttgga ttacaatgag 1450

 gcaaagggtg tgtatgaaaa agttggagaa gctacagaga ctgctctcac 1500

 ttgcctagta gagaagatga atgtatttga taccgaattg aagggtcttt 1550

 ctaaaataga acgtgcaaat gcctgcaact cagtcattaa acagctgatg 1600

 aaaaaggaat tcactctaga gttttcacgt gacagaaagt caatgtcggt 1650

 ttactgtaca ccaaataaac caagcaggac atcaatgagc aagatgtttg 1700

 tgaagggtgc tcctgaaggt gtcattgaca ggtgcaccca cattcgagtt 1750

 ggaagtacta aggttcctat gacctctgga gtcaaacaga agatcatgtc 1800

 tgtcattcga gagtggggta gtggcagcga cacactgcga tgcctggccc 1850

 tggccactca tgacaaccca ctgagaagag aagaaatgca ccttgaggac 1900

 tctgccaact ttattaaata tgagaccaat ctgaccttcg ttggctgcgt 1950

 gggcatgctg gatcctccga gaatcgaggt ggcctcctcc gtgaagctgt 2000

 gccggcaagc aggcatccgg gtcatcatga tcactgggga caacaagggc 2050

 actgctgtgg ccatctgtcg ccgcatcggc atcttcgggc aggatgagga 2100

 cgtgacgtca aaagctttca caggccggga gtttgatgaa ctcaacccct 2150

 ccgcccagcg agacgcctgc ctgaacgccc gctgttttgc tcgagttgaa 2200

 ccctcccaca agtctaaaat cgtagaattt cttcagtctt ttgatgagat 2250

 tacagctatg actggcgatg gcgtgaacga tgctcctgct ctgaagaaag 2300

 ccgagattgg cattgctatg ggctctggca ctgcggtggc taaaaccgcc 2350

 tctgagatgg tcctggcgga tgacaacttc tccaccattg tggctgccgt 2400

 tgaggagggg cgggcaatct acaacaacat gaaacagttc atccgctacc 2450

 tcatctcgtc caacgtcggg gaagttgtct gtattttcct gacagcagcc 2500

 cttggatttc ccgaggcttt gattcctgtt cagctgctct gggtcaatct 2550

 ggtgacagat ggcctgcctg ccactgcact ggggttcaac cctcctgatc 2600

 tggacatcat gaataaacct ccccggaacc caaaggaacc attgatcagc 2650

 gggtggctct ttttccgtta cttggctatt ggctgttacg tcggcgctgc 2700

 taccgtgggt gctgctgcat ggtggttcat tgctgctgac ggtggtccaa 2750

 gagtgtcctt ctaccagctg agtcatttcc tacagtgtaa agaggacaac 2800

 ccggactttg aaggcgtgga ttgtgcaatc tttgaatccc catacccgat 2850

 gacaatggcg ctctctgttc tagtaactat agaaatgtgt aacgccctca 2900

 acagcttgtc cgaaaaccag tccttgctga ggatgccccc ctgggagaac 2950

 atctggctcg tgggctccat ctgcctgtcc atgtcactcc acttcctgat 3000

 cctctatgtc gaacccttgc cactcatctt ccagatcaca ccgctgaacg 3050

 tgacccagtg gctgatggtg ctgaaaatct ccttgcccgt gattctcatg 3100

 gatgagacgc tcaagtttgt ggcccgcaac tacctggaac ctggtaaaga 3150

 gtgtgtgcag cctgccacca aatcctgctc gttctcggca tgcaccgatg 3200

 ggatttcctg gccgtttgtg ctgctcataa tgcccctggt gatctgggtc 3250

 tatagcacag acactaactt tagcgatatg ttctggtctt gactgacagt 3300

 tttccataaa gaagatgttt aacttaatca attaattttt ttattgttta 3350

 aagcaactgt ctatttctgc tgaattttca catgaacata ctggctggtg 3400

 atggaggttt catactctag attttgtttt gctttttctg actccagtgg 3450

 ggcaagattt tcctttttta tacacataat taaagtgtcc attgacatgt 3500

 acagagaact aacactattt tatgcaaata tttttttgta gatgaaaaag 3550

 catgtacagt gttctgttta atactcatcc ttgtataaaa aaaatagttg 3600

 agccagcaga cattgtcagc aaattaattg gcagcagatt ttaggaaatg 3650

 aatgtgtgtg gttttttttc taaaactaaa tagcatgtat tgtgtctttt 3700

 gcatgatgat ccggatttaa tttgatatca cagtctaatt tttattcata 3750

 agccaatttt tctgcactga gcagagtctt gctacctcag tcagtattgt 3800

 tttggtttgc tacttccctc acccactttg gcctccgttc accccacccc 3850

 accccacctc tccccacctt acccccgccc cgcttggctt cttctttagg 3900

 attgtgatgg ttcgttctgt ttacatcagt tttaacgaga ggtatgcctg 3950

 tactcgcttg tgcagaaaac attgttccag attcaatcga ctgggtttat 4000

 gtcccttcac atagttttta aggttattta tttaaatgtc taatgtattt 4050

 tattgtaaca gacattgttt tgccaacatt gcctatttca gtggcacgtc 4100

 atctagtttt aaaaaaataa aacattttaa atggacagag aaaaaaaaaa 4150

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4200

 aaaaa 4205

<210> 1957
<211> 1042
<212> PRT
<213> Homo sapien

<400> 1957
 Met Glu Asn Ala His Thr Lys Thr Val Glu Glu Val Leu Gly His
   1               5                  10                  15

 Phe Gly Val Asn Glu Ser Thr Gly Leu Ser Leu Glu Gln Val Lys
                  20                  25                  30

 Lys Leu Lys Glu Arg Trp Gly Ser Asn Glu Leu Pro Ala Glu Glu
                  35                  40                  45

 Gly Lys Thr Leu Leu Glu Leu Val Ile Glu Gln Phe Glu Asp Leu
                  50                  55                  60

 Leu Val Arg Ile Leu Leu Leu Ala Ala Cys Ile Ser Phe Val Leu
                  65                  70                  75

 Ala Trp Phe Glu Glu Gly Glu Glu Thr Ile Thr Ala Phe Val Glu
                  80                  85                  90

 Pro Phe Val Ile Leu Leu Ile Leu Val Ala Asn Ala Ile Val Gly
                  95                 100                 105

 Val Trp Gln Glu Arg Asn Ala Glu Asn Ala Ile Glu Ala Leu Lys
                 110                 115                 120

 Glu Tyr Glu Pro Glu Met Gly Lys Val Tyr Arg Gln Asp Arg Lys
                 125                 130                 135

 Ser Val Gln Arg Ile Lys Ala Lys Asp Ile Val Pro Gly Asp Ile
                 140                 145                 150

 Val Glu Ile Ala Val Gly Asp Lys Val Pro Ala Asp Ile Arg Leu
                 155                 160                 165

 Thr Ser Ile Lys Ser Thr Thr Leu Arg Val Asp Gln Ser Ile Leu
                 170                 175                 180

 Thr Gly Glu Ser Val Ser Val Ile Lys His Thr Asp Pro Val Pro
                 185                 190                 195

 Asp Pro Arg Ala Val Asn Gln Asp Lys Lys Asn Met Leu Phe Ser
                 200                 205                 210

 Gly Thr Asn Ile Ala Ala Gly Lys Ala Met Gly Val Val Val Ala
                 215                 220                 225

 Thr Gly Val Asn Thr Glu Ile Gly Lys Ile Arg Asp Glu Met Val
                 230                 235                 240

 Ala Thr Glu Gln Glu Arg Thr Pro Leu Gln Gln Lys Leu Asp Glu
                 245                 250                 255

 Phe Gly Glu Gln Leu Ser Lys Val Ile Ser Leu Ile Cys Ile Ala
                 260                 265                 270

 Val Trp Ile Ile Asn Ile Gly His Phe Asn Asp Pro Val His Gly
                 275                 280                 285

 Gly Ser Trp Ile Arg Gly Ala Ile Tyr Tyr Phe Lys Ile Ala Val
                 290                 295                 300

 Ala Leu Ala Val Ala Ala Ile Pro Glu Gly Leu Pro Ala Val Ile
                 305                 310                 315

 Thr Thr Cys Leu Ala Leu Gly Thr Arg Arg Met Ala Lys Lys Asn
                 320                 325                 330

 Ala Ile Val Arg Ser Leu Pro Ser Val Glu Thr Leu Gly Cys Thr
                 335                 340                 345

 Ser Val Ile Cys Ser Asp Lys Thr Gly Thr Leu Thr Thr Asn Gln
                 350                 355                 360

 Met Ser Val Cys Arg Met Phe Ile Leu Asp Arg Val Glu Gly Asp
                 365                 370                 375

 Thr Cys Ser Leu Asn Glu Phe Thr Ile Thr Gly Ser Thr Tyr Ala
                 380                 385                 390

 Pro Ile Gly Glu Val His Lys Asp Asp Lys Pro Val Asn Cys His
                 395                 400                 405

 Gln Tyr Asp Gly Leu Val Glu Leu Ala Thr Ile Cys Ala Leu Cys
                 410                 415                 420

 Asn Asp Ser Ala Leu Asp Tyr Asn Glu Ala Lys Gly Val Tyr Glu
                 425                 430                 435

 Lys Val Gly Glu Ala Thr Glu Thr Ala Leu Thr Cys Leu Val Glu
                 440                 445                 450

 Lys Met Asn Val Phe Asp Thr Glu Leu Lys Gly Leu Ser Lys Ile
                 455                 460                 465

 Glu Arg Ala Asn Ala Cys Asn Ser Val Ile Lys Gln Leu Met Lys
                 470                 475                 480

 Lys Glu Phe Thr Leu Glu Phe Ser Arg Asp Arg Lys Ser Met Ser
                 485                 490                 495

 Val Tyr Cys Thr Pro Asn Lys Pro Ser Arg Thr Ser Met Ser Lys
                 500                 505                 510

 Met Phe Val Lys Gly Ala Pro Glu Gly Val Ile Asp Arg Cys Thr
                 515                 520                 525

 His Ile Arg Val Gly Ser Thr Lys Val Pro Met Thr Ser Gly Val
                 530                 535                 540

 Lys Gln Lys Ile Met Ser Val Ile Arg Glu Trp Gly Ser Gly Ser
                 545                 550                 555

 Asp Thr Leu Arg Cys Leu Ala Leu Ala Thr His Asp Asn Pro Leu
                 560                 565                 570

 Arg Arg Glu Glu Met His Leu Glu Asp Ser Ala Asn Phe Ile Lys
                 575                 580                 585

 Tyr Glu Thr Asn Leu Thr Phe Val Gly Cys Val Gly Met Leu Asp
                 590                 595                 600

 Pro Pro Arg Ile Glu Val Ala Ser Ser Val Lys Leu Cys Arg Gln
                 605                 610                 615

 Ala Gly Ile Arg Val Ile Met Ile Thr Gly Asp Asn Lys Gly Thr
                 620                 625                 630

 Ala Val Ala Ile Cys Arg Arg Ile Gly Ile Phe Gly Gln Asp Glu
                 635                 640                 645

 Asp Val Thr Ser Lys Ala Phe Thr Gly Arg Glu Phe Asp Glu Leu
                 650                 655                 660

 Asn Pro Ser Ala Gln Arg Asp Ala Cys Leu Asn Ala Arg Cys Phe
                 665                 670                 675

 Ala Arg Val Glu Pro Ser His Lys Ser Lys Ile Val Glu Phe Leu
                 680                 685                 690

 Gln Ser Phe Asp Glu Ile Thr Ala Met Thr Gly Asp Gly Val Asn
                 695                 700                 705

 Asp Ala Pro Ala Leu Lys Lys Ala Glu Ile Gly Ile Ala Met Gly
                 710                 715                 720

 Ser Gly Thr Ala Val Ala Lys Thr Ala Ser Glu Met Val Leu Ala
                 725                 730                 735

 Asp Asp Asn Phe Ser Thr Ile Val Ala Ala Val Glu Glu Gly Arg
                 740                 745                 750

 Ala Ile Tyr Asn Asn Met Lys Gln Phe Ile Arg Tyr Leu Ile Ser
                 755                 760                 765

 Ser Asn Val Gly Glu Val Val Cys Ile Phe Leu Thr Ala Ala Leu
                 770                 775                 780

 Gly Phe Pro Glu Ala Leu Ile Pro Val Gln Leu Leu Trp Val Asn
                 785                 790                 795

 Leu Val Thr Asp Gly Leu Pro Ala Thr Ala Leu Gly Phe Asn Pro
                 800                 805                 810

 Pro Asp Leu Asp Ile Met Asn Lys Pro Pro Arg Asn Pro Lys Glu
                 815                 820                 825

 Pro Leu Ile Ser Gly Trp Leu Phe Phe Arg Tyr Leu Ala Ile Gly
                 830                 835                 840

 Cys Tyr Val Gly Ala Ala Thr Val Gly Ala Ala Ala Trp Trp Phe
                 845                 850                 855

 Ile Ala Ala Asp Gly Gly Pro Arg Val Ser Phe Tyr Gln Leu Ser
                 860                 865                 870

 His Phe Leu Gln Cys Lys Glu Asp Asn Pro Asp Phe Glu Gly Val
                 875                 880                 885

 Asp Cys Ala Ile Phe Glu Ser Pro Tyr Pro Met Thr Met Ala Leu
                 890                 895                 900

 Ser Val Leu Val Thr Ile Glu Met Cys Asn Ala Leu Asn Ser Leu
                 905                 910                 915

 Ser Glu Asn Gln Ser Leu Leu Arg Met Pro Pro Trp Glu Asn Ile
                 920                 925                 930

 Trp Leu Val Gly Ser Ile Cys Leu Ser Met Ser Leu His Phe Leu
                 935                 940                 945

 Ile Leu Tyr Val Glu Pro Leu Pro Leu Ile Phe Gln Ile Thr Pro
                 950                 955                 960

 Leu Asn Val Thr Gln Trp Leu Met Val Leu Lys Ile Ser Leu Pro
                 965                 970                 975

 Val Ile Leu Met Asp Glu Thr Leu Lys Phe Val Ala Arg Asn Tyr
                 980                 985                 990

 Leu Glu Pro Gly Lys Glu Cys Val Gln Pro Ala Thr Lys Ser Cys
                 995                1000                1005

 Ser Phe Ser Ala Cys Thr Asp Gly Ile Ser Trp Pro Phe Val Leu
                1010                1015                1020

 Leu Ile Met Pro Leu Val Ile Trp Val Tyr Ser Thr Asp Thr Asn
                1025                1030                1035

 Phe Ser Asp Met Phe Trp Ser
                1040

<210> 1958
<211> 2084
<212> DNA
<213> Mus musculus

<400> 1958
 aaccgcatct gcagcgagca actgagaagc caagactgag ccggcggccg 50

 cggcgcagcg aacgagcagt gaccgtgctc ctacccagct ctgcttcaca 100

 gcgcccacct gtctccgccc ctcggcccct cgcccggctt tgcctaaccg 150

 ccacgatgat gttctcgggc ttcaacgcag actacgaggc gtcatcctcc 200

 cgctgcagca gcgcgtcccc ggccggggat agcctctctt actaccactc 250

 acccgcagac tccttctcca gcatgggctc gcctgtcaac gcgcaggact 300

 tctgcacgga cctggccgtc tccagtgcca acttcattcc cacggtcact 350

 gccatctcga ccagtccgga cctgcagtgg ctggtgcagc ccgccctcgt 400

 ctcctctgtg gccccatcgc agaccagagc ccctcaccct ttcggagtcc 450

 ccgccccctc cgctggggct tactccaggg ctggcgttgt gaagaccatg 500

 acaggaggcc gagcgcagag cattggcagg aggggcaagg tggaacagtt 550

 atctccagaa gaagaagaga aaaggagaat ccgaagggaa aggaataaga 600

 tggctgcagc caaatgccgc aaccggagga gggagctgac tgatacactc 650

 caagcggaga cagaccaact agaagatgag aagtctgctt tgcagaccga 700

 gattgccaac ctgctgaagg agaaggaaaa actagagttc atcctggcag 750

 ctcaccgacc tgcctgcaag atccctgatg acctgggctt cccagaagag 800

 atgtctgtgg cttcccttga tctgactggg ggcctgccag aggttgccac 850

 cccggagtct gaggaggcct tcaccctgcc tctcctcaat gaccctgagc 900

 ccaagccctc agtggaacct gtcaagagca tcagcagcat ggagctgaag 950

 accgagccct ttgatgactt cctgttccca gcatcatcca ggcccagtgg 1000

 ctctgagaca gcccgctccg tgccagacat ggacctatct gggtccttct 1050

 atgcagcaga ctgggagcct ctgcacagtg gctccctggg gatggggccc 1100

 atggccacag agctggagcc cctgtgcact ccggtggtca cctgtactcc 1150

 cagctgcact gcttacacgt cttccttcgt cttcacctac cccgaggctg 1200

 actccttccc cagctgtgca gctgcccacc gcaagggcag cagcagcaat 1250

 gagccttcct ctgactcgct cagctcaccc acgctgctgg ccctgtgagg 1300

 gggcagggaa ggggaggcag ccggcaccca caagtgccac tgcccgagct 1350

 ggtgcattac agagaggaga aacacatctt ccctagaggg ttcctgtaga 1400

 cctagggagg accttatctg tgcgtgaaac acaccaggct gtgggcctca 1450

 aggacttgaa agcatccatg tgtggactca agtccttacc tcttccggag 1500

 atgtagcaaa acgcatggag tgtgtattgt tcccagtgac acttcagaga 1550

 gctggtagtt agtagcatgt tgagccaggc ctgggtctgt gtctcttttc 1600

 tctttctcct tagtcttctc atagcattaa ctaatctatt gggttcatta 1650

 ttggaattaa cctggtgctg gatattttca aattgtatct agtgcagctg 1700

 attttaacaa taactactgt gttcctggca atagtgtgtt ctgattagaa 1750

 atgaccaata ttatactaag aaaagatacg actttatttt ctggtagata 1800

 gaaataaata gctatatcca tgtactgtag tttttcttca acatcaatgt 1850

 tcattgtaat gttactgatc atgcattgtt gaggtggtct gaatgttctg 1900

 acattaacag ttttccatga aaacgtttta ttgtgttttt aatttattta 1950

 ttaagatgga ttctcagata tttatatttt tattttattt ttttctacct 2000

 tgaggtcttt tgacatgtgg aaagtgaatt tgaatgaaaa atttaagcat 2050

 tgtttgctta ttgttccaag acattgtcaa taaa 2084

<210> 1959
<211> 380
<212> PRT
<213> Mus musculus

<400> 1959
 Met Met Phe Ser Gly Phe Asn Ala Asp Tyr Glu Ala Ser Ser Ser
   1               5                  10                  15

 Arg Cys Ser Ser Ala Ser Pro Ala Gly Asp Ser Leu Ser Tyr Tyr
                  20                  25                  30

 His Ser Pro Ala Asp Ser Phe Ser Ser Met Gly Ser Pro Val Asn
                  35                  40                  45

 Ala Gln Asp Phe Cys Thr Asp Leu Ala Val Ser Ser Ala Asn Phe
                  50                  55                  60

 Ile Pro Thr Val Thr Ala Ile Ser Thr Ser Pro Asp Leu Gln Trp
                  65                  70                  75

 Leu Val Gln Pro Ala Leu Val Ser Ser Val Ala Pro Ser Gln Thr
                  80                  85                  90

 Arg Ala Pro His Pro Phe Gly Val Pro Ala Pro Ser Ala Gly Ala
                  95                 100                 105

 Tyr Ser Arg Ala Gly Val Val Lys Thr Met Thr Gly Gly Arg Ala
                 110                 115                 120

 Gln Ser Ile Gly Arg Arg Gly Lys Val Glu Gln Leu Ser Pro Glu
                 125                 130                 135

 Glu Glu Glu Lys Arg Arg Ile Arg Arg Glu Arg Asn Lys Met Ala
                 140                 145                 150

 Ala Ala Lys Cys Arg Asn Arg Arg Arg Glu Leu Thr Asp Thr Leu
                 155                 160                 165

 Gln Ala Glu Thr Asp Gln Leu Glu Asp Glu Lys Ser Ala Leu Gln
                 170                 175                 180

 Thr Glu Ile Ala Asn Leu Leu Lys Glu Lys Glu Lys Leu Glu Phe
                 185                 190                 195

 Ile Leu Ala Ala His Arg Pro Ala Cys Lys Ile Pro Asp Asp Leu
                 200                 205                 210

 Gly Phe Pro Glu Glu Met Ser Val Ala Ser Leu Asp Leu Thr Gly
                 215                 220                 225

 Gly Leu Pro Glu Val Ala Thr Pro Glu Ser Glu Glu Ala Phe Thr
                 230                 235                 240

 Leu Pro Leu Leu Asn Asp Pro Glu Pro Lys Pro Ser Val Glu Pro
                 245                 250                 255

 Val Lys Ser Ile Ser Ser Met Glu Leu Lys Thr Glu Pro Phe Asp
                 260                 265                 270

 Asp Phe Leu Phe Pro Ala Ser Ser Arg Pro Ser Gly Ser Glu Thr
                 275                 280                 285

 Ala Arg Ser Val Pro Asp Met Asp Leu Ser Gly Ser Phe Tyr Ala
                 290                 295                 300

 Ala Asp Trp Glu Pro Leu His Ser Gly Ser Leu Gly Met Gly Pro
                 305                 310                 315

 Met Ala Thr Glu Leu Glu Pro Leu Cys Thr Pro Val Val Thr Cys
                 320                 325                 330

 Thr Pro Ser Cys Thr Ala Tyr Thr Ser Ser Phe Val Phe Thr Tyr
                 335                 340                 345

 Pro Glu Ala Asp Ser Phe Pro Ser Cys Ala Ala Ala His Arg Lys
                 350                 355                 360

 Gly Ser Ser Ser Asn Glu Pro Ser Ser Asp Ser Leu Ser Ser Pro
                 365                 370                 375

 Thr Leu Leu Ala Leu
                 380

<210> 1960
<211> 1679
<212> DNA
<213> Homo sapien

<400> 1960
 gtttgttggc tgcggcagca ggtagcaaag tgacgccgag ggcctgagtg 50

 ctccagtagc caccgcatct ggagaaccag cggttaccat ggaggggatc 100

 agtatataca cttcagataa ctacaccgag gaaatgggct caggggacta 150

 tgactccatg aaggaaccct gtttccgtga agaaaatgct aatttcaata 200

 aaatcttcct gcccaccatc tactccatca tcttcttaac tggcattgtg 250

 ggcaatggat tggtcatcct ggtcatgggt taccagaaga aactgagaag 300

 catgacggac aagtacaggc tgcacctgtc agtggccgac ctcctctttg 350

 tcatcacgct tcccttctgg gcagttgatg ccgtggcaaa ctggtacttt 400

 gggaacttcc tatgcaaggc agtccatgtc atctacacag tcaacctcta 450

 cagcagtgtc ctcatcctgg ccttcatcag tctggaccgc tacctggcca 500

 tcgtccacgc caccaacagt cagaggccaa ggaagctgtt ggctgaaaag 550

 gtggtctatg ttggcgtctg gatccctgcc ctcctgctga ctattcccga 600

 cttcatcttt gccaacgtca gtgaggcaga tgacagatat atctgtgacc 650

 gcttctaccc caatgacttg tgggtggttg tgttccagtt tcagcacatc 700

 atggttggcc ttatcctgcc tggtattgtc atcctgtcct gctattgcat 750

 tatcatctcc aagctgtcac actccaaggg ccaccagaag cgcaaggccc 800

 tcaagaccac agtcatcctc atcctggctt tcttcgcctg ttggctgcct 850

 tactacattg ggatcagcat cgactccttc atcctcctgg aaatcatcaa 900

 gcaagggtgt gagtttgaga acactgtgca caagtggatt tccatcaccg 950

 aggccctagc tttcttccac tgttgtctga accccatcct ctatgctttc 1000

 cttggagcca aatttaaaac ctctgcccag cacgcactca cctctgtgag 1050

 cagagggtcc agcctcaaga tcctctccaa aggaaagcga ggtggacatt 1100

 catctgtttc cactgagtct gagtcttcaa gttttcactc cagctaacac 1150

 agatgtaaaa gacttttttt tatacgataa ataacttttt tttaagttac 1200

 acatttttca gatataaaag actgaccaat attgtacagt ttttattgct 1250

 tgttggattt ttgtcttgtg tttctttagt ttttgtgaag tttaattgac 1300

 ttatttatat aaattttttt tgtttcatat tgatgtgtgt ctaggcagga 1350

 cctgtggcca agttcttagt tgctgtatgt ctcgtggtag gactgtagaa 1400

 aagggaactg aacattccag agcgtgtagt gaatcacgta aagctagaaa 1450

 tgatccccag ctgtttatgc atagataatc tctccattcc cgtggaacgt 1500

 ttttcctgtt cttaagacgt gattttgctg tagaagatgg cacttataac 1550

 caaagcccaa agtggtatag aaatgctggt ttttcagttt tcaggagtgg 1600

 gttgatttca gcacctacag tgtacagtct tgtattaagt tgttaataaa 1650

 agtacatgtt aaacttactt agtgttatg 1679

<210> 1961
<211> 352
<212> PRT
<213> Homo sapien

<400> 1961
 Met Glu Gly Ile Ser Ile Tyr Thr Ser Asp Asn Tyr Thr Glu Glu
   1               5                  10                  15

 Met Gly Ser Gly Asp Tyr Asp Ser Met Lys Glu Pro Cys Phe Arg
                  20                  25                  30

 Glu Glu Asn Ala Asn Phe Asn Lys Ile Phe Leu Pro Thr Ile Tyr
                  35                  40                  45

 Ser Ile Ile Phe Leu Thr Gly Ile Val Gly Asn Gly Leu Val Ile
                  50                  55                  60

 Leu Val Met Gly Tyr Gln Lys Lys Leu Arg Ser Met Thr Asp Lys
                  65                  70                  75

 Tyr Arg Leu His Leu Ser Val Ala Asp Leu Leu Phe Val Ile Thr
                  80                  85                  90

 Leu Pro Phe Trp Ala Val Asp Ala Val Ala Asn Trp Tyr Phe Gly
                  95                 100                 105

 Asn Phe Leu Cys Lys Ala Val His Val Ile Tyr Thr Val Asn Leu
                 110                 115                 120

 Tyr Ser Ser Val Leu Ile Leu Ala Phe Ile Ser Leu Asp Arg Tyr
                 125                 130                 135

 Leu Ala Ile Val His Ala Thr Asn Ser Gln Arg Pro Arg Lys Leu
                 140                 145                 150

 Leu Ala Glu Lys Val Val Tyr Val Gly Val Trp Ile Pro Ala Leu
                 155                 160                 165

 Leu Leu Thr Ile Pro Asp Phe Ile Phe Ala Asn Val Ser Glu Ala
                 170                 175                 180

 Asp Asp Arg Tyr Ile Cys Asp Arg Phe Tyr Pro Asn Asp Leu Trp
                 185                 190                 195

 Val Val Val Phe Gln Phe Gln His Ile Met Val Gly Leu Ile Leu
                 200                 205                 210

 Pro Gly Ile Val Ile Leu Ser Cys Tyr Cys Ile Ile Ile Ser Lys
                 215                 220                 225

 Leu Ser His Ser Lys Gly His Gln Lys Arg Lys Ala Leu Lys Thr
                 230                 235                 240

 Thr Val Ile Leu Ile Leu Ala Phe Phe Ala Cys Trp Leu Pro Tyr
                 245                 250                 255

 Tyr Ile Gly Ile Ser Ile Asp Ser Phe Ile Leu Leu Glu Ile Ile
                 260                 265                 270

 Lys Gln Gly Cys Glu Phe Glu Asn Thr Val His Lys Trp Ile Ser
                 275                 280                 285

 Ile Thr Glu Ala Leu Ala Phe Phe His Cys Cys Leu Asn Pro Ile
                 290                 295                 300

 Leu Tyr Ala Phe Leu Gly Ala Lys Phe Lys Thr Ser Ala Gln His
                 305                 310                 315

 Ala Leu Thr Ser Val Ser Arg Gly Ser Ser Leu Lys Ile Leu Ser
                 320                 325                 330

 Lys Gly Lys Arg Gly Gly His Ser Ser Val Ser Thr Glu Ser Glu
                 335                 340                 345

 Ser Ser Ser Phe His Ser Ser
                 350

<210> 1962
<211> 1410
<212> DNA
<213> Homo sapien

<400> 1962
 gagctagctt tgcaatatgg cggccgaggc ggacggaccg cttaaacggc 50

 tgctcgtgcc gattctttta cctgagaaat gctacgacca acttttcgtt 100

 cagtgggact tgcttcacgt cccctgcctc aagattctcc tcagcaaagg 150

 cctggggctg ggcattgtgg ctggctcact tctagtaaag ctgccccagg 200

 tgtttaaaat ccggggagcc aagagtgctg aagggttgag tctccagtct 250

 gtaatgctgg agctagtggc attgactggg accatggtct acagcatcac 300

 taacaacttc ccattcagct cttggggtga agccttattc ctgatgctcc 350

 agacgatcac catctgcttc ctggtcatgc actacagagg acagactgtg 400

 aaaggtgtcg ctttcctcgc ttgctacggc ctggtcctgc tggtgcttct 450

 ctcacctctg acgcccttga ctgtagtcac cctgctccag gcctccaatg 500

 tgcctgctgt ggtggtgggg aggcttctcc aggcagccac caactaccac 550

 aacgggtaca caggccagct ctcagccatc acagtcttcc tgctgtttgg 600

 gggctccctg gcccgaatct tcacttccat tcaggaaacc ggagatcccc 650

 tgatggctgg gacctttgtg gtctcctctc tctgcaacgg cctcatcgcc 700

 gcccagctgc tcttctactg gaatgcaaag cctccccaca agcagaaaaa 750

 ggcgcagtag agccagctac tggagtcatt ccgtttccac tcattcaccc 800

 aacctcaggg ttctccccat ctgagccagc ctgctggtgt gacttactca 850

 tcctccattc ctctgcactt gcagactttc tgagccaggg ttttctttta 900

 gtggaaacaa atggttgatg gatccagatc cttagaaaag gagaggatgg 950

 gggtagagtc tcccaagcca aaattttgac atttgagtgc tttcgtaagc 1000

 cctgtacatg tactattaat tcagtcattc agccaagcct cctcctctag 1050

 cagcaatttc cagctgttta acactatcct gggcaaatgt tttaccctgt 1100

 cctccagcct ccctgcttcc cttctggccc tggaagactg agtctggacg 1150

 gcagagtgga gggactggga ggctgtggct gcctccctcc ctcagcccgg 1200

 ctgggactgt ctcccggacc ccagtgctgg ggtgggggaa gggggacgga 1250

 gaatgactca ggcagggccc cagggtgggg tgaggaggtt cctgctctgg 1300

 caggtctagg cggaagggag tggagatggg gctggttgct gctgcagtga 1350

 ggggaacaga tgggacaata aagactggag actcagttga ataatgcaaa 1400

 aaaaaaaaaa 1410

<210> 1963
<211> 247
<212> PRT
<213> Homo sapien

<400> 1963
 Met Ala Ala Glu Ala Asp Gly Pro Leu Lys Arg Leu Leu Val Pro
   1               5                  10                  15

 Ile Leu Leu Pro Glu Lys Cys Tyr Asp Gln Leu Phe Val Gln Trp
                  20                  25                  30

 Asp Leu Leu His Val Pro Cys Leu Lys Ile Leu Leu Ser Lys Gly
                  35                  40                  45

 Leu Gly Leu Gly Ile Val Ala Gly Ser Leu Leu Val Lys Leu Pro
                  50                  55                  60

 Gln Val Phe Lys Ile Arg Gly Ala Lys Ser Ala Glu Gly Leu Ser
                  65                  70                  75

 Leu Gln Ser Val Met Leu Glu Leu Val Ala Leu Thr Gly Thr Met
                  80                  85                  90

 Val Tyr Ser Ile Thr Asn Asn Phe Pro Phe Ser Ser Trp Gly Glu
                  95                 100                 105

 Ala Leu Phe Leu Met Leu Gln Thr Ile Thr Ile Cys Phe Leu Val
                 110                 115                 120

 Met His Tyr Arg Gly Gln Thr Val Lys Gly Val Ala Phe Leu Ala
                 125                 130                 135

 Cys Tyr Gly Leu Val Leu Leu Val Leu Leu Ser Pro Leu Thr Pro
                 140                 145                 150

 Leu Thr Val Val Thr Leu Leu Gln Ala Ser Asn Val Pro Ala Val
                 155                 160                 165

 Val Val Gly Arg Leu Leu Gln Ala Ala Thr Asn Tyr His Asn Gly
                 170                 175                 180

 Tyr Thr Gly Gln Leu Ser Ala Ile Thr Val Phe Leu Leu Phe Gly
                 185                 190                 195

 Gly Ser Leu Ala Arg Ile Phe Thr Ser Ile Gln Glu Thr Gly Asp
                 200                 205                 210

 Pro Leu Met Ala Gly Thr Phe Val Val Ser Ser Leu Cys Asn Gly
                 215                 220                 225

 Leu Ile Ala Ala Gln Leu Leu Phe Tyr Trp Asn Ala Lys Pro Pro
                 230                 235                 240

 His Lys Gln Lys Lys Ala Gln
                 245

<210> 1964
<211> 1758
<212> DNA
<213> Homo sapien

<400> 1964
 cgccccttta gggtgctcgc cggctgtcgg gtgtgggggt atgccaggcc 50

 ccggaggact cggcttcccc gctaacccga cccgccgcac cccacccagg 100

 ccaggtcaga gcagcccacc atgggatggg gagggggtgg aggctgcacc 150

 ccccgcccac ccatccacca gcagccgccg gagcgccgcg tggtcatcgt 200

 tgtctttctc ggcctcctgc tggacctcct ggccttcacg ctgctgctgc 250

 ccctgctgcc cgggctgttg gagagccacg gccgtgccca cgaccccctc 300

 tatggctcct ggcagggcgg ggtggactgg tttgccaccg ccatcgggat 350

 gccagtggag aagaggtaca acagtgtcct gttcggaggt ctcattggct 400

 cggcattctc tgtcctgcag tttctgtgtg cgccactcac tggggccacc 450

 tctgactgct tggggaggcg cccggtgatg ctgctgtgcc tgatgggtgt 500

 ggccacctca tatgcagtct gggccacctc tcggagcttt gcggccttcc 550

 tggcctccag gctgattggg ggcatcagca aagggaacgt cagcctctcc 600

 acggccatcg ttgctgacct gggctcgcct ctggcccgca gtcaaggcat 650

 ggcggtcatt ggggtggcct tctcactggg cttcaccctg ggccctatgc 700

 tcggagcctc cctgcccctg gaaatggcac cctggtttgc cctgctcttc 750

 gcagcctccg acctgctgtt catcttctgc ttcctgccag agacgctgcc 800

 cctggagaaa cgggcgccct ctatcgccct ggggttccgt gatgcggctg 850

 atctgctcag ccccctggcc ctgctgcgct tctcggctgt cgctcgtggc 900

 caggacccac cctctggaga caggctcagc agcctgcgcc gcctgggcct 950

 agtctacttc ctctacctct tcctgttctc gggcctggag tacacgctga 1000

 gcttcctcac acaccagcgc ttccagttca gtagcctaca gcaggggaag 1050

 atgtttttcc tcatcggcct caccatggcc accatccagg gtgcctatgc 1100

 ccggcggatc caccctggcg gggaagttgc tgccgtgaag cgggccctcc 1150

 tgctgctggt gcccgccttc ctcctcatcg gctggggacg ttctctgccc 1200

 gtgctgggcc tggggctgct gctctactcc tttgccgccg ccgttgtggt 1250

 gccctgcctg tcctccgtgg tcgctggcta tggctcacca gggcagaagg 1300

 gcacggtcat gggtacactg cgcagcctag gtgctctggc cagggccgcg 1350

 gggcccctgg tggccgcttc agtgtactgg ctggccgggg cccaggcctg 1400

 cttcaccacg tggtccgggc tctttttgct ccccttcttc ctcctgcaga 1450

 agctgagtta cccggcacag acgctcaagg ctgagtagct gagccactgt 1500

 gcccaggctg tgggcaccag gcagagtggg agcctaggtc aggcccctgc 1550

 ccactgcctg acccccaccc cccgccagtc cagggagacc ctgtgggtgg 1600

 gggccggccc ctaagcagga agctcaggca gctcctccag acttacttac 1650

 tccttcagtg actccgagct gcagcactcc aaggctgtca gggcttctgt 1700

 ttgtttttta aactatgcac caggtttctg atgatgaaat aaagcacctg 1750

 tttgtttt 1758

<210> 1965
<211> 455
<212> PRT
<213> Homo sapien

<400> 1965
 Met Gly Trp Gly Gly Gly Gly Gly Cys Thr Pro Arg Pro Pro Ile
   1               5                  10                  15

 His Gln Gln Pro Pro Glu Arg Arg Val Val Ile Val Val Phe Leu
                  20                  25                  30

 Gly Leu Leu Leu Asp Leu Leu Ala Phe Thr Leu Leu Leu Pro Leu
                  35                  40                  45

 Leu Pro Gly Leu Leu Glu Ser His Gly Arg Ala His Asp Pro Leu
                  50                  55                  60

 Tyr Gly Ser Trp Gln Gly Gly Val Asp Trp Phe Ala Thr Ala Ile
                  65                  70                  75

 Gly Met Pro Val Glu Lys Arg Tyr Asn Ser Val Leu Phe Gly Gly
                  80                  85                  90

 Leu Ile Gly Ser Ala Phe Ser Val Leu Gln Phe Leu Cys Ala Pro
                  95                 100                 105

 Leu Thr Gly Ala Thr Ser Asp Cys Leu Gly Arg Arg Pro Val Met
                 110                 115                 120

 Leu Leu Cys Leu Met Gly Val Ala Thr Ser Tyr Ala Val Trp Ala
                 125                 130                 135

 Thr Ser Arg Ser Phe Ala Ala Phe Leu Ala Ser Arg Leu Ile Gly
                 140                 145                 150

 Gly Ile Ser Lys Gly Asn Val Ser Leu Ser Thr Ala Ile Val Ala
                 155                 160                 165

 Asp Leu Gly Ser Pro Leu Ala Arg Ser Gln Gly Met Ala Val Ile
                 170                 175                 180

 Gly Val Ala Phe Ser Leu Gly Phe Thr Leu Gly Pro Met Leu Gly
                 185                 190                 195

 Ala Ser Leu Pro Leu Glu Met Ala Pro Trp Phe Ala Leu Leu Phe
                 200                 205                 210

 Ala Ala Ser Asp Leu Leu Phe Ile Phe Cys Phe Leu Pro Glu Thr
                 215                 220                 225

 Leu Pro Leu Glu Lys Arg Ala Pro Ser Ile Ala Leu Gly Phe Arg
                 230                 235                 240

 Asp Ala Ala Asp Leu Leu Ser Pro Leu Ala Leu Leu Arg Phe Ser
                 245                 250                 255

 Ala Val Ala Arg Gly Gln Asp Pro Pro Ser Gly Asp Arg Leu Ser
                 260                 265                 270

 Ser Leu Arg Arg Leu Gly Leu Val Tyr Phe Leu Tyr Leu Phe Leu
                 275                 280                 285

 Phe Ser Gly Leu Glu Tyr Thr Leu Ser Phe Leu Thr His Gln Arg
                 290                 295                 300

 Phe Gln Phe Ser Ser Leu Gln Gln Gly Lys Met Phe Phe Leu Ile
                 305                 310                 315

 Gly Leu Thr Met Ala Thr Ile Gln Gly Ala Tyr Ala Arg Arg Ile
                 320                 325                 330

 His Pro Gly Gly Glu Val Ala Ala Val Lys Arg Ala Leu Leu Leu
                 335                 340                 345

 Leu Val Pro Ala Phe Leu Leu Ile Gly Trp Gly Arg Ser Leu Pro
                 350                 355                 360

 Val Leu Gly Leu Gly Leu Leu Leu Tyr Ser Phe Ala Ala Ala Val
                 365                 370                 375

 Val Val Pro Cys Leu Ser Ser Val Val Ala Gly Tyr Gly Ser Pro
                 380                 385                 390

 Gly Gln Lys Gly Thr Val Met Gly Thr Leu Arg Ser Leu Gly Ala
                 395                 400                 405

 Leu Ala Arg Ala Ala Gly Pro Leu Val Ala Ala Ser Val Tyr Trp
                 410                 415                 420

 Leu Ala Gly Ala Gln Ala Cys Phe Thr Thr Trp Ser Gly Leu Phe
                 425                 430                 435

 Leu Leu Pro Phe Phe Leu Leu Gln Lys Leu Ser Tyr Pro Ala Gln
                 440                 445                 450

 Thr Leu Lys Ala Glu
                 455

<210> 1966
<211> 1641
<212> DNA
<213> Homo sapien

<400> 1966
 ggcacgaggc cagtgatgga ttcaagcctc gtgaacgaag cggtggggag 50

 caggcacagg actgggatgc tctgccaccc aagcggcccc gactaggggc 100

 aggaaacaag atcggaggcc gtaggcttat tgtggtgctg gaaggggcca 150

 gtctggagac agtcaaggta gggaagacat atgagctact caactgtgac 200

 aagcacaagt ctatattgtt gaagaatgga cgggaccctg gggaagcgcg 250

 gccagatatc acccaccaga gtttgctgat gctgatggat agtcccctga 300

 accgagctgg cttgctacag gtttatatcc atacacagaa gaatgttctg 350

 attgaagtga atccccagac ccgaattccc agaacctttg accgcttttg 400

 tggcctcatg gttcaacttt tacacaagct cagtgttcga gcagctgatg 450

 gcccccagaa gcttttgaag gtaattaaga atccagtatc agatcacttt 500

 ccagttggat gtatgaaagt tggcacttct ttttccatcc cggttgtcag 550

 tgatgtgcgt gagctggtgc ccagcagtga tcctattgtt tttgtggtag 600

 gggcctttgc ccatggcaag gtcagtgtgg agtatacaga gaagatggtg 650

 tccatcagta actaccccct ttctgctgcc ctcacctgtg caaaacttac 700

 cacagccttt gaggaagtat ggggggtcat ttgacagtag tagaacctgt 750

 tctgaaacca gaaactgttg atgtcacatc ctttgaccct ggtctgagct 800

 gactgctgga agatgatctt tctgcactga gactgtggag tttggggaag 850

 ccaaggctgt acatttgcta tttgtttatc ctatgaatac tgttcttgca 900

 aacctggttg ttttggggtt cctaaagtat ccagtggtgt aaaactgttt 950

 gttccccggg acttcaggga cagataggag gttacagagt ttgcagtttg 1000

 gttccatgct ttgaaggcag gctttagctc ccagattccc atgtgctaaa 1050

 ggagagaacc ctgatgatgg agaagaactg tgaaagagag cagtcaggaa 1100

 tgctagtggt gaaaaactga acaaacagaa gtgattttat ctaatacagt 1150

 tccaaggtag aaaaagtgga gcaggcaggg ccttgcaccc ctctccaccc 1200

 ccccatgggg ggggtggtgg tagcggcaca tacacaatca tagtaaattg 1250

 gcagaagaaa aacacaatag attcctggct agatggggag agataaggca 1300

 atgtgcatgg gggaatcaga ggggagatgt gagcccctct gctcctccca 1350

 caagagtttc ccctttgggc cgggcacggt ggctcacgcc tgtaatccca 1400

 gcactttggg aggcggaggc gggtggatca cttgcggtca ggagttcgag 1450

 accagcctgg ccaacgtggt gaaatcccgt ttctactgaa aatacaaaaa 1500

 ttagctgggc atggtggcgt gcctgtattc ccaaagtgct gggattacag 1550

 gcatcactgg cccaggcaga gccaattctg tataataaat ctgtctctct 1600

 ctgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1641

<210> 1967
<211> 151
<212> PRT
<213> Homo sapien

<400> 1967
 Met Leu Met Asp Ser Pro Leu Asn Arg Ala Gly Leu Leu Gln Val
   1               5                  10                  15

 Tyr Ile His Thr Gln Lys Asn Val Leu Ile Glu Val Asn Pro Gln
                  20                  25                  30

 Thr Arg Ile Pro Arg Thr Phe Asp Arg Phe Cys Gly Leu Met Val
                  35                  40                  45

 Gln Leu Leu His Lys Leu Ser Val Arg Ala Ala Asp Gly Pro Gln
                  50                  55                  60

 Lys Leu Leu Lys Val Ile Lys Asn Pro Val Ser Asp His Phe Pro
                  65                  70                  75

 Val Gly Cys Met Lys Val Gly Thr Ser Phe Ser Ile Pro Val Val
                  80                  85                  90

 Ser Asp Val Arg Glu Leu Val Pro Ser Ser Asp Pro Ile Val Phe
                  95                 100                 105

 Val Val Gly Ala Phe Ala His Gly Lys Val Ser Val Glu Tyr Thr
                 110                 115                 120

 Glu Lys Met Val Ser Ile Ser Asn Tyr Pro Leu Ser Ala Ala Leu
                 125                 130                 135

 Thr Cys Ala Lys Leu Thr Thr Ala Phe Glu Glu Val Trp Gly Val
                 140                 145                 150

 Ile


<210> 1968
<211> 3552
<212> DNA
<213> Homo sapien

<400> 1968
 tgagccggcc gcacgcggag gatcctaagg agcagctctg ttgcgacata 50

 ggccgagcag cgaggcccag ctccctgaaa caacagtaac ctacccctgt 100

 gggtcatcat catgccctcc gacctggcca agaagaaggc agccaaaaag 150

 aaggaggctg ccaaagctcg acagcggccc agaaaaggac atgaagaaaa 200

 tggagatgtt gtcacagaac cacaggtggc agagaagaat gaggccaatg 250

 gcagagagac cacagaagta gatttgctga ccaaggagct agaggacttt 300

 gagatgaaga aagctgctgc tcgagctgtc actggcgtcc tggcctctca 350

 ccccaacagt actgatgttc acatcatcaa cctctcactt acctttcatg 400

 gtcaagagct gctcagtgac accaaactgg aattaaactc aggccgtcgt 450

 tatggcctca ttggtttaaa tggaattgga aagtccatgc tgctctctgc 500

 tattgggaag cgtgaagtgc ccatccctga gcacatcgac atctaccatc 550

 tgactcgaga gatgccccct agtgacaaga cacccttgca ttgtgtgatg 600

 gaagtcgaca cagagcgggc catgctggag aaagaggcag agcggctggc 650

 tcatgaggat gcggagtgtg agaagctcat ggagctctac gagcgcctgg 700

 aggagctgga tgccgacaag gcagagatga gggcctcgcg gatcttgcat 750

 ggactgggtt tcacacctgc catgcagcgc aagaagctaa aagacttcag 800

 tgggggctgg aggatgaggg ttgcccttgc cagagccctc tttattcggc 850

 ccttcatgct gctcctggat gagcctacca accacctgga cctagatgct 900

 tgcgtgtggt tggaagaaga actaaaaact tttaagcgca tcttggtcct 950

 cgtctcccat tcccaggatt ttctgaatgg tgtctgtacc aatatcattc 1000

 acatgcacaa caagaaactg aagtattata cgggtaatta tgatcagtac 1050

 gtgaagacgc ggctagagct ggaggagaac cagatgaaga ggtttcactg 1100

 ggagcaagat cagattgcac acatgaagaa ctacattgcg aggtttggtc 1150

 atggcagtgc caagctggcc cggcaggccc agagcaagga gaagacgcta 1200

 cagaaaatga tggcatcagg actgacagag agggtcgtga gcgataagac 1250

 actgtcattt tatttcccac catgtggcaa gatccctcca cctgtcatta 1300

 tggtgcaaaa tgtgagcttc aagtatacaa aagatgggcc ttgcatctac 1350

 aataatctag aatttggaat tgaccttgac acacgagtgg ctctggtagg 1400

 gcccaatgga gcagggaagt caactcttct gaagctgcta actggagagc 1450

 tactacccac agatggcatg atccgaaaac actctcatgt caagataggg 1500

 cgttaccatc agcatttaca agagcagctg gacttagatc tctcaccttt 1550

 ggagtacatg atgaagtgct acccagagat caaggagaag gaagaaatga 1600

 ggaagatcat tgggcgatac ggtctcactg ggaaacaaca ggtgagccca 1650

 atccggaact tgtcagacgg gcagaagtgc cgagtgtgtc tggcctggct 1700

 ggcctggcag aacccccaca tgctcttcct ggatgaaccc accaatcacc 1750

 tggatatcga gaccatcgac gccctggcag atgccatcaa tgagtttgag 1800

 ggtggtatga tgctggtcag ccatgacttc agactcattc agcaggttgc 1850

 acaggaaatt tgggtctgtg agaagcagac aatcaccaag tggcctggag 1900

 acatcctggc ttacaaggag cacctcaagt ccaagctggt ggatgaggag 1950

 ccccagctca ccaagaggac ccacaacgtg tgagccctct acctgggttc 2000

 gggtcaggag ctccatctgg gaactaacag ctgctaacct gaccagccgc 2050

 tcaggacagg accctggggc tacactcctg cattgctgca atactgctcc 2100

 cccagcctct cccctgcccc tcaacctgcc ttagctgcac tctcttacct 2150

 acagctggac agtacctgtc tgtttcctgt cctccttcca gttacatctg 2200

 tccatgtctg gactcggctg gccgttccct ccagcccctt gctggttatc 2250

 ttactctgag tgtgatgcag tcagaggcac ctgcgggtta gcccaggggc 2300

 ccaagccctg gatttggcct gcggaggagc ttaggatcct cgttttctgg 2350

 gttttggtga tgttggagga gtacccccca gcccaccgcc ccgattcctt 2400

 tttgcttctg gtttggagct ccggaccagg accttcgtcc tggtcagttt 2450

 ttaaataatt atttagcagt gtaactttta gacctgcgtg acatctacaa 2500

 agcgcccaat aaagaaagag gaagccacgg tccctacctt ccttctcggg 2550

 tctctggggc cttctcctcc ctgcagtgcc aacatgcact gcccacagca 2600

 ggagctggat ccagcgtcag tgtgtcgatg ggaactgaag actagtccat 2650

 aggagctgga agaactttgt ccctttactt ctgatttgaa attgtacctt 2700

 ttctcaggcc tgtgattcac agactttaac atgaatcaga atcacctgga 2750

 gggctcatgc aatcagattg ccagatctcg cctcagcgtt tctggttcaa 2800

 taggttttgg gggagaccaa gaacgttaac atttctagca agtttccagg 2850

 tgatgctgtt gttgctggtc tagagactat tttgagaacc actgtccagg 2900

 agcgtggttt tctgattgtg atctgaggtt ctgccccaac tgcacagcag 2950

 ttgggctgct tgttaaaaat gcaggccagg tgcggtggct cacacctgta 3000

 atcccagcgc tttgggaggc tgaggcaggt ggatcacttg agctcaggag 3050

 ttcaagacca gcttgggaaa catggcaaaa cccgtcttta tgtgcctgga 3100

 atcccacctg ctcaggtggc tagggtggat ggatcgcttg agcccaggag 3150

 gtggaggttg cagtgagctg agattgcacc actgcattcc agcctggatg 3200

 acagagcaaa accctgtctc aaaaaaatgc agactggcca ggcacagtgg 3250

 ctcacacctg taatccgact gtaagctcat caccttggga ggccactgta 3300

 ggaggatcaa ttgagcctag aagttcaaga ccagcctggg caaagtaggg 3350

 agaccccttc tctacaaata gtaataaaat gaaccgggca tagtagcatg 3400

 tgcctgcggt cccagctgct ctgataagag gaggctcact tgagcccagg 3450

 aggttgaggc tgcagtgagc agagcgtgcc gctacactcc agcctgatga 3500

 cagaccgaga cactgtctca aaaaaataaa aaaattcaga ttgctgaaaa 3550

 aa 3552

<210> 1969
<211> 623
<212> PRT
<213> Homo sapien

<400> 1969
 Met Pro Ser Asp Leu Ala Lys Lys Lys Ala Ala Lys Lys Lys Glu
   1               5                  10                  15

 Ala Ala Lys Ala Arg Gln Arg Pro Arg Lys Gly His Glu Glu Asn
                  20                  25                  30

 Gly Asp Val Val Thr Glu Pro Gln Val Ala Glu Lys Asn Glu Ala
                  35                  40                  45

 Asn Gly Arg Glu Thr Thr Glu Val Asp Leu Leu Thr Lys Glu Leu
                  50                  55                  60

 Glu Asp Phe Glu Met Lys Lys Ala Ala Ala Arg Ala Val Thr Gly
                  65                  70                  75

 Val Leu Ala Ser His Pro Asn Ser Thr Asp Val His Ile Ile Asn
                  80                  85                  90

 Leu Ser Leu Thr Phe His Gly Gln Glu Leu Leu Ser Asp Thr Lys
                  95                 100                 105

 Leu Glu Leu Asn Ser Gly Arg Arg Tyr Gly Leu Ile Gly Leu Asn
                 110                 115                 120

 Gly Ile Gly Lys Ser Met Leu Leu Ser Ala Ile Gly Lys Arg Glu
                 125                 130                 135

 Val Pro Ile Pro Glu His Ile Asp Ile Tyr His Leu Thr Arg Glu
                 140                 145                 150

 Met Pro Pro Ser Asp Lys Thr Pro Leu His Cys Val Met Glu Val
                 155                 160                 165

 Asp Thr Glu Arg Ala Met Leu Glu Lys Glu Ala Glu Arg Leu Ala
                 170                 175                 180

 His Glu Asp Ala Glu Cys Glu Lys Leu Met Glu Leu Tyr Glu Arg
                 185                 190                 195

 Leu Glu Glu Leu Asp Ala Asp Lys Ala Glu Met Arg Ala Ser Arg
                 200                 205                 210

 Ile Leu His Gly Leu Gly Phe Thr Pro Ala Met Gln Arg Lys Lys
                 215                 220                 225

 Leu Lys Asp Phe Ser Gly Gly Trp Arg Met Arg Val Ala Leu Ala
                 230                 235                 240

 Arg Ala Leu Phe Ile Arg Pro Phe Met Leu Leu Leu Asp Glu Pro
                 245                 250                 255

 Thr Asn His Leu Asp Leu Asp Ala Cys Val Trp Leu Glu Glu Glu
                 260                 265                 270

 Leu Lys Thr Phe Lys Arg Ile Leu Val Leu Val Ser His Ser Gln
                 275                 280                 285

 Asp Phe Leu Asn Gly Val Cys Thr Asn Ile Ile His Met His Asn
                 290                 295                 300

 Lys Lys Leu Lys Tyr Tyr Thr Gly Asn Tyr Asp Gln Tyr Val Lys
                 305                 310                 315

 Thr Arg Leu Glu Leu Glu Glu Asn Gln Met Lys Arg Phe His Trp
                 320                 325                 330

 Glu Gln Asp Gln Ile Ala His Met Lys Asn Tyr Ile Ala Arg Phe
                 335                 340                 345

 Gly His Gly Ser Ala Lys Leu Ala Arg Gln Ala Gln Ser Lys Glu
                 350                 355                 360

 Lys Thr Leu Gln Lys Met Met Ala Ser Gly Leu Thr Glu Arg Val
                 365                 370                 375

 Val Ser Asp Lys Thr Leu Ser Phe Tyr Phe Pro Pro Cys Gly Lys
                 380                 385                 390

 Ile Pro Pro Pro Val Ile Met Val Gln Asn Val Ser Phe Lys Tyr
                 395                 400                 405

 Thr Lys Asp Gly Pro Cys Ile Tyr Asn Asn Leu Glu Phe Gly Ile
                 410                 415                 420

 Asp Leu Asp Thr Arg Val Ala Leu Val Gly Pro Asn Gly Ala Gly
                 425                 430                 435

 Lys Ser Thr Leu Leu Lys Leu Leu Thr Gly Glu Leu Leu Pro Thr
                 440                 445                 450

 Asp Gly Met Ile Arg Lys His Ser His Val Lys Ile Gly Arg Tyr
                 455                 460                 465

 His Gln His Leu Gln Glu Gln Leu Asp Leu Asp Leu Ser Pro Leu
                 470                 475                 480

 Glu Tyr Met Met Lys Cys Tyr Pro Glu Ile Lys Glu Lys Glu Glu
                 485                 490                 495

 Met Arg Lys Ile Ile Gly Arg Tyr Gly Leu Thr Gly Lys Gln Gln
                 500                 505                 510

 Val Ser Pro Ile Arg Asn Leu Ser Asp Gly Gln Lys Cys Arg Val
                 515                 520                 525

 Cys Leu Ala Trp Leu Ala Trp Gln Asn Pro His Met Leu Phe Leu
                 530                 535                 540

 Asp Glu Pro Thr Asn His Leu Asp Ile Glu Thr Ile Asp Ala Leu
                 545                 550                 555

 Ala Asp Ala Ile Asn Glu Phe Glu Gly Gly Met Met Leu Val Ser
                 560                 565                 570

 His Asp Phe Arg Leu Ile Gln Gln Val Ala Gln Glu Ile Trp Val
                 575                 580                 585

 Cys Glu Lys Gln Thr Ile Thr Lys Trp Pro Gly Asp Ile Leu Ala
                 590                 595                 600

 Tyr Lys Glu His Leu Lys Ser Lys Leu Val Asp Glu Glu Pro Gln
                 605                 610                 615

 Leu Thr Lys Arg Thr His Asn Val
                 620

<210> 1970
<211> 1558
<212> DNA
<213> Homo sapien

<400> 1970
 cttggtagtc tgttagtggg agatccttgt tgccgtccct tcgcctcctt 50

 caccgccgca gaccccttca agttctagtc atgcgtgagt gcatctccat 100

 ccacgttggc caggctggtg tccagattgg caatgcctgc tgggagctct 150

 actgcctgga acacggcatc cagcccgatg gccagatgcc aagtgacaag 200

 accattgggg gaggagatga ttccttcaac accttcttca gtgaaacggg 250

 tgctggcaag catgtgcccc gggcagtgtt tgtagacttg gaacccacag 300

 tcattgatga agttcgcact ggcacctacc gccagctctt ccaccctgag 350

 cagctcatca caggcaagga agatgctgcc aataactatg cccgagggca 400

 ctacaccatt ggcaaggaga tcattgacct cgtgttggac cgaattcgca 450

 agctggctga ccagtgcacc ggtcttcagg gcttcttggt tttccacagc 500

 tttggtgggg gaactggttc tgggttcacc tcgctgctca tggaacgtct 550

 ctcagttgat tatggcaaga agtccaagct ggagttctct atttacccgg 600

 cgccccaggt ttccacagct gtagttgagc cctacaactc catcctcacc 650

 acccacacca ccctggagca ctctgattgt gccttcatgg tagacaatga 700

 ggccatctat gacatctgtc gtagaaacct cgatatcgag cgcccaacct 750

 acactaacct taaccgcctt attagccaga ttgtgtcctc catcactgct 800

 tccctgagat ttgatggagc cctgaatgtt gacctgacag aattccagac 850

 caacctggtg ccctaccccc gcatccactt ccctctggcc acatatgccc 900

 ctgtcatctc tgctgagaaa gcctaccatg aacagcttac tgtagcagag 950

 atcaccaatg cttgctttga gccagccaac cagatggtga aatgtgaccc 1000

 tcgccatggt aaatacatgg cttgctgcct gttataccgt ggtgacgtgg 1050

 ttcccaaaga tgtcaatgct gccattgcca ccatcaaaac caagcgtacc 1100

 atccagtttg tggattggtg ccccactggc ttcaaggttg gcattaatta 1150

 ccagcctccc actgtggtgc ctggcggaga cctggccaag gtacagagag 1200

 ctgtgtgcat gctgagcaat accacagctg ttgctgaggc ctgggctcgc 1250

 ctggaccaca agtttgacct gatgtatgcc aagcgtgcct ttgttcactg 1300

 gtacgtgggt gaggggatgg aggaaggcga gttttcagag gcccgtgagg 1350

 acatggctgc ccttgagaag gattatgagg aggttggagc agatagtgct 1400

 gacggagagg atgagggtga agagtattaa cctgtgtgct gtacttttac 1450

 actcctttgt cttggaactg tcttattttt gttctgtaaa tgtctattgc 1500

 cgtaaattgt taataaaatt gatgtttcca ttttaaaaaa aaaaaaaaaa 1550

 aaaaaaaa 1558

<210> 1971
<211> 449
<212> PRT
<213> Homo sapien

<400> 1971
 Met Arg Glu Cys Ile Ser Ile His Val Gly Gln Ala Gly Val Gln
   1               5                  10                  15

 Ile Gly Asn Ala Cys Trp Glu Leu Tyr Cys Leu Glu His Gly Ile
                  20                  25                  30

 Gln Pro Asp Gly Gln Met Pro Ser Asp Lys Thr Ile Gly Gly Gly
                  35                  40                  45

 Asp Asp Ser Phe Asn Thr Phe Phe Ser Glu Thr Gly Ala Gly Lys
                  50                  55                  60

 His Val Pro Arg Ala Val Phe Val Asp Leu Glu Pro Thr Val Ile
                  65                  70                  75

 Asp Glu Val Arg Thr Gly Thr Tyr Arg Gln Leu Phe His Pro Glu
                  80                  85                  90

 Gln Leu Ile Thr Gly Lys Glu Asp Ala Ala Asn Asn Tyr Ala Arg
                  95                 100                 105

 Gly His Tyr Thr Ile Gly Lys Glu Ile Ile Asp Leu Val Leu Asp
                 110                 115                 120

 Arg Ile Arg Lys Leu Ala Asp Gln Cys Thr Gly Leu Gln Gly Phe
                 125                 130                 135

 Leu Val Phe His Ser Phe Gly Gly Gly Thr Gly Ser Gly Phe Thr
                 140                 145                 150

 Ser Leu Leu Met Glu Arg Leu Ser Val Asp Tyr Gly Lys Lys Ser
                 155                 160                 165

 Lys Leu Glu Phe Ser Ile Tyr Pro Ala Pro Gln Val Ser Thr Ala
                 170                 175                 180

 Val Val Glu Pro Tyr Asn Ser Ile Leu Thr Thr His Thr Thr Leu
                 185                 190                 195

 Glu His Ser Asp Cys Ala Phe Met Val Asp Asn Glu Ala Ile Tyr
                 200                 205                 210

 Asp Ile Cys Arg Arg Asn Leu Asp Ile Glu Arg Pro Thr Tyr Thr
                 215                 220                 225

 Asn Leu Asn Arg Leu Ile Ser Gln Ile Val Ser Ser Ile Thr Ala
                 230                 235                 240

 Ser Leu Arg Phe Asp Gly Ala Leu Asn Val Asp Leu Thr Glu Phe
                 245                 250                 255

 Gln Thr Asn Leu Val Pro Tyr Pro Arg Ile His Phe Pro Leu Ala
                 260                 265                 270

 Thr Tyr Ala Pro Val Ile Ser Ala Glu Lys Ala Tyr His Glu Gln
                 275                 280                 285

 Leu Thr Val Ala Glu Ile Thr Asn Ala Cys Phe Glu Pro Ala Asn
                 290                 295                 300

 Gln Met Val Lys Cys Asp Pro Arg His Gly Lys Tyr Met Ala Cys
                 305                 310                 315

 Cys Leu Leu Tyr Arg Gly Asp Val Val Pro Lys Asp Val Asn Ala
                 320                 325                 330

 Ala Ile Ala Thr Ile Lys Thr Lys Arg Thr Ile Gln Phe Val Asp
                 335                 340                 345

 Trp Cys Pro Thr Gly Phe Lys Val Gly Ile Asn Tyr Gln Pro Pro
                 350                 355                 360

 Thr Val Val Pro Gly Gly Asp Leu Ala Lys Val Gln Arg Ala Val
                 365                 370                 375

 Cys Met Leu Ser Asn Thr Thr Ala Val Ala Glu Ala Trp Ala Arg
                 380                 385                 390

 Leu Asp His Lys Phe Asp Leu Met Tyr Ala Lys Arg Ala Phe Val
                 395                 400                 405

 His Trp Tyr Val Gly Glu Gly Met Glu Glu Gly Glu Phe Ser Glu
                 410                 415                 420

 Ala Arg Glu Asp Met Ala Ala Leu Glu Lys Asp Tyr Glu Glu Val
                 425                 430                 435

 Gly Ala Asp Ser Ala Asp Gly Glu Asp Glu Gly Glu Glu Tyr
                 440                 445

<210> 1972
<211> 3246
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2530
<223> Unknown base

<400> 1972
 agtgtggttt tagtttttcc taagaagtgg cgtggtttgg ggctttatat 50

 ccgggaggag catatgtacg caaatcctgg ggcgtttgca aacccggatc 100

 cggggcgtct ggccccatgc ccggccgggc gtttgagggc tactgccacg 150

 cagcgtttct ggagcctgcc ggctggtgcc ctggtggcct ttatctctgt 200

 ccccctttgt cctctttatc tcaggctctc caggaggccg gggggcccac 250

 tccgcctatc gctcccctcg gctacgctgc cactccaatg ccccgcaggt 300

 cgcgagctgc tgttctttcg aaggcgccgg agaaccaggg gcgtcccgcg 350

 ccacctctga ctcggagcag cgccgagcac tgacgctccc gcccttgggc 400

 aaggacgcca gtgcgcccgc gcgcgtccct ctgcgcggca gcccgtcgcg 450

 ggccctcaag gggaagccca ggccaggatg gccccgggtc gcgcggtggc 500

 cgggctcctg ttgctggcgg ccgccggcct cggaggagtg gcggaggggc 550

 cagggctagc cttcagcgag gatgtgctga gcgtgttcgg cgcgaatctg 600

 agcctgtcgg cggcgcagct ccagcacttg ctggagcaga tgggagccgc 650

 ctcccgcgtg ggcgtcccgg agcctggcca gctgcacttc aaccagtgtt 700

 taactgctga agagatcttt tcccttcatg gcttttcaaa tgctacccaa 750

 ataaccagct ccaaattctc tgtcatctgt ccagcagtct tacagcaatt 800

 gaactttcac ccatgtgagg atcggcccaa gcacaaaaca agaccaagtc 850

 attcagaagt ttggggatat ggattcctgt cagtgacgat tattaatctg 900

 gcatctctcc tcggattgat tttgactcca ctgataaaga aatcttattt 950

 cccaaagatt ttgacctttt ttgtggggct ggctattggg actctttttt 1000

 caaatgcaat tttccaactt attccagagg catttggatt tgatcccaaa 1050

 gtcgacagtt atgttgagaa ggcagttgct gtgtttggtg gattttacct 1100

 acttttcttt tttgaaagaa tgctaaagat gttattaaag acatatggtc 1150

 agaatggtca tacccacttt ggaaatgata actttggtcc tcaagaaaaa 1200

 actcatcaac ctaaagcatt acctgccatc aatggtgtga catgctatgc 1250

 aaatcctgct gtcacagaag ctaatggaca tatccatttt gataatgtca 1300

 gtgtggtatc tctacaggat ggaaaaaaag agccaagttc atgtacctgt 1350

 ttgaaggggc ccaaactgtc agaaataggg acgattgcct ggatgataac 1400

 gctctgcgat gccctccaca atttcatcga tggcctggcg attggggctt 1450

 cctgcacctt gtctctcctt cagggactca gtacttccat agcaatccta 1500

 tgtgaggagt ttccccacga gttaggagac tttgtgatcc tactcaatgc 1550

 agggatgagc actcgacaag ccttgctatt caacttcctt tctgcatgtt 1600

 cctgctatgt tgggctagct tttggcattt tggtgggcaa caatttcgct 1650

 ccaaatatta tatttgcact tgctggaggc atgttcctct atatttctct 1700

 ggcagatatg tttccagaga tgaatgatat gctgagagaa aaggtaactg 1750

 gaagaaaaac cgatttcacc ttcttcatga ttcagaatgc tggaatgtta 1800

 actggattca cagccattct actcattacc ttgtatgcag gagaaatcga 1850

 attggagtaa tagaaaatgg aagatggtgt tgttaataaa ggcatttaat 1900

 agataaaaac atctccaaaa aggattttga agctgatcct atttagttaa 1950

 aaagataatt ttgctttcaa ctgtaggtcc agaaaactaa ttattggcat 2000

 cagtctgtga aatagtccat tatttgttgt taaaaatgct tcaaaaggtt 2050

 ttcagtgtca gtctgagatg cctggtatat aggagccttt gggaaatact 2100

 tatttttcag tattccatgc atattagata tcaccatgaa gcaagagaca 2150

 tgcattctat aatcatgtag acactcagac tcaggggaaa atacaagtta 2200

 tatcctgaaa gcctttaaaa ctctatggta ggatcaaaga ttcaaatggt 2250

 ttcagagagg ttttatttca attaatttgt tctagtgctt tcaagagcaa 2300

 gtacatcaaa atgtagaagg taaaatgtat gcaacactaa tataaattat 2350

 tccaagtctt taaggagcca aagaaaaaaa agatttctca cagctttttg 2400

 ttctgttttg tatttcaatt aggaacttgc agtattattt tgaaaaccat 2450

 tctaaaataa taggagttag gaaataaata aagttttgct agccctgcta 2500

 agttcaggct tagaggctta tcgctaagtn taaacttcac cagattccac 2550

 gaaaagctgg atagcttttt ttctgactta tgttgtggtt gcacccctca 2600

 caaatggcag aacagtatgt aaagctggta acacctcggt ttcagtgcac 2650

 catgtgtttg ctttgtgaag gtgaagaata tgttggttta gagaaagaaa 2700

 ttggatgtaa ttttatgcaa tttactttta aagacaaaca taactattta 2750

 gcagagaata ttttaataaa tgcaaaacaa cagctggact gctgtacatc 2800

 aaggacagat taactggaaa acatatgttc cttatgtgtg attgagagcc 2850

 attcagaaaa gacttccttt gtgttcagcc tatacttttc catatggtat 2900

 accttgaaaa aaattagcac accatggtta tttttctacc ttttataaaa 2950

 gacagagcct gtttactcat ttagaagata gagaaaattg gtctaaaatt 3000

 gaacatccta gattcacact cccaagtcac ttaaggtgat ttgatggtga 3050

 ggaaaatgat tgacaaagcc caacaatgat ctcaggaatt acattttcca 3100

 acagaccaaa aaatgttttc atgtagcagc aatgcagatt tggtgaatat 3150

 ttaatatata ttttagtatg tatttcactt tatgactgac aattaaaaaa 3200

 tattgtttgg ccaaatagta aacacccttt tgaaaccatg aaaaaa 3246

<210> 1973
<211> 460
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2530
<223> Unknown amino acid

<400> 1973
 Met Ala Pro Gly Arg Ala Val Ala Gly Leu Leu Leu Leu Ala Ala
   1               5                  10                  15

 Ala Gly Leu Gly Gly Val Ala Glu Gly Pro Gly Leu Ala Phe Ser
                  20                  25                  30

 Glu Asp Val Leu Ser Val Phe Gly Ala Asn Leu Ser Leu Ser Ala
                  35                  40                  45

 Ala Gln Leu Gln His Leu Leu Glu Gln Met Gly Ala Ala Ser Arg
                  50                  55                  60

 Val Gly Val Pro Glu Pro Gly Gln Leu His Phe Asn Gln Cys Leu
                  65                  70                  75

 Thr Ala Glu Glu Ile Phe Ser Leu His Gly Phe Ser Asn Ala Thr
                  80                  85                  90

 Gln Ile Thr Ser Ser Lys Phe Ser Val Ile Cys Pro Ala Val Leu
                  95                 100                 105

 Gln Gln Leu Asn Phe His Pro Cys Glu Asp Arg Pro Lys His Lys
                 110                 115                 120

 Thr Arg Pro Ser His Ser Glu Val Trp Gly Tyr Gly Phe Leu Ser
                 125                 130                 135

 Val Thr Ile Ile Asn Leu Ala Ser Leu Leu Gly Leu Ile Leu Thr
                 140                 145                 150

 Pro Leu Ile Lys Lys Ser Tyr Phe Pro Lys Ile Leu Thr Phe Phe
                 155                 160                 165

 Val Gly Leu Ala Ile Gly Thr Leu Phe Ser Asn Ala Ile Phe Gln
                 170                 175                 180

 Leu Ile Pro Glu Ala Phe Gly Phe Asp Pro Lys Val Asp Ser Tyr
                 185                 190                 195

 Val Glu Lys Ala Val Ala Val Phe Gly Gly Phe Tyr Leu Leu Phe
                 200                 205                 210

 Phe Phe Glu Arg Met Leu Lys Met Leu Leu Lys Thr Tyr Gly Gln
                 215                 220                 225

 Asn Gly His Thr His Phe Gly Asn Asp Asn Phe Gly Pro Gln Glu
                 230                 235                 240

 Lys Thr His Gln Pro Lys Ala Leu Pro Ala Ile Asn Gly Val Thr
                 245                 250                 255

 Cys Tyr Ala Asn Pro Ala Val Thr Glu Ala Asn Gly His Ile His
                 260                 265                 270

 Phe Asp Asn Val Ser Val Val Ser Leu Gln Asp Gly Lys Lys Glu
                 275                 280                 285

 Pro Ser Ser Cys Thr Cys Leu Lys Gly Pro Lys Leu Ser Glu Ile
                 290                 295                 300

 Gly Thr Ile Ala Trp Met Ile Thr Leu Cys Asp Ala Leu His Asn
                 305                 310                 315

 Phe Ile Asp Gly Leu Ala Ile Gly Ala Ser Cys Thr Leu Ser Leu
                 320                 325                 330

 Leu Gln Gly Leu Ser Thr Ser Ile Ala Ile Leu Cys Glu Glu Phe
                 335                 340                 345

 Pro His Glu Leu Gly Asp Phe Val Ile Leu Leu Asn Ala Gly Met
                 350                 355                 360

 Ser Thr Arg Gln Ala Leu Leu Phe Asn Phe Leu Ser Ala Cys Ser
                 365                 370                 375

 Cys Tyr Val Gly Leu Ala Phe Gly Ile Leu Val Gly Asn Asn Phe
                 380                 385                 390

 Ala Pro Asn Ile Ile Phe Ala Leu Ala Gly Gly Met Phe Leu Tyr
                 395                 400                 405

 Ile Ser Leu Ala Asp Met Phe Pro Glu Met Asn Asp Met Leu Arg
                 410                 415                 420

 Glu Lys Val Thr Gly Arg Lys Thr Asp Phe Thr Phe Phe Met Ile
                 425                 430                 435

 Gln Asn Ala Gly Met Leu Thr Gly Phe Thr Ala Ile Leu Leu Ile
                 440                 445                 450

 Thr Leu Tyr Ala Gly Glu Ile Glu Leu Glu
                 455                 460

<210> 1974
<211> 3089
<212> DNA
<213> Homo sapien

<400> 1974
 gggggccctc cgcaggttca gtcctcgcgt cggccgcccc gcgctcagtc 50

 gcgcgcacct tctctcgcgg ccgggggacc gcagcgcggg gctagcccgg 100

 agacccggcc accggcctgg ggcgccttca cgccgtctcg gagcggataa 150

 tgcggtgagc aggcaccacg ccggcagact cggctggatc tgcgcacagc 200

 ggcagggatt gcgtgcgccc gcgggaggcc cggggcagcg gctgggatcc 250

 tcagcggcgg ccggtttgtc ctggttgtgg tcaagactgg atgatgtaac 300

 tggctctcta ggaagcctca cttggccgta acctcaggaa ggttctcttt 350

 gaccccatct catttcgaag ccacttctga agccacttga gaaaaatgat 400

 gtgacagttc ctatcaaaaa ggattcagaa acatatacca tctgtgaaga 450

 aagtggccct ttctcccgct tgcaaaatag acattctcaa attccaaaat 500

 gccagccaag accccaattt acctgaaagc agccaataac aagaaaggaa 550

 agaaatttaa actgagggac attctgtctc ctgatatgat cagtcccccg 600

 cttggagact ttcgccacac catccacatt ggcaaagagg gccagcacga 650

 tgtctttgga gatatttcct ttcttcaagg gaactacgag cttttacctg 700

 gaaaccagga gaaagcacac ctgggccagt tccctgggca taatgagttc 750

 ttccgggcca acagcacctc ggactctgtg ttcacagaaa cgccctcccc 800

 ggtgctcaaa aatgccatct ccctcccgac cattggagga tcccaagctc 850

 tcatgttgcc cttattgtca ccagtgacat ttaattccaa acaggagtcc 900

 ttcgggccag caaagctgcc caggcttagc tgcgagcccg tcatggagga 950

 aaaagctcag gagaaaagca gtctgttgga gaatgggaca gtccaccagg 1000

 gagacacctc gtggggctcc agcggttctg catctcagtc cagccaaggc 1050

 agagacagcc actcctccag cctgtccgaa cagtaccccg actggccagc 1100

 cgaggacatg tttgaccatc ccaccccatg cgagctcatc aagggaaaga 1150

 ctaagtcaga ggagtccctc tctgacctta caggttccct cctctccctg 1200

 cagcttgatc ttgggccctc acttttggat gaggtgctga atgtaatgga 1250

 taaaaataag taacaagatg ccaacttttt tcctttgggg taaaaggtac 1300

 aaaaacaaac taaccacagt tgaagagaag ggcttccgga gctgtatttg 1350

 cagttttgtg ttgggttttc taaaataata ttcttacaaa gtattttttt 1400

 acctgttatg ccctgtttgc aaaaacaatt tagaaaaaaa caacaaagca 1450

 aaacctatct tggcaaaaaa aggaagtgag tcagagccca ttttcaggag 1500

 gcattggtga tgttcggctc acatattgtt tgcagacaca caagaaatct 1550

 ggcttggcca ggattggcac tagctatgaa gggctgagcg agtcacatta 1600

 aggaacttca cggaacttta tagcactccg acattttctg agcaagagga 1650

 agtcaaaatt tatttaacac ctaagccttt ttgtagactc ttttctatat 1700

 attgcttagg ctcaccatag tgaattctcc agtgttaaaa cttttctgtt 1750

 ttcacatttg aactttatgg gttttgggga ttttcttgta gttcttatat 1800

 atccctatat attatatcta tattgcaaaa ttttgactgt cagctacatg 1850

 ttggtaagac acaggcaaag tattactgta actaagttat ttttaaagtt 1900

 aaaatatatt tttacgtgcc tttggctttt tattgcagag tctacatttt 1950

 atagattcta catcagatgt tgtcacttat ttccattggg attccattgt 2000

 aagctgtgta tgtgcgtgtt tggaaaagtg tattcatact tagttttttt 2050

 ttcttcatct gttatcatac ttttaacagc aaccaataac ggattgtaaa 2100

 gtgtaaaggc acaggttact catgatgctt ctgcagagac tgtgggctac 2150

 accacatatg ttatttggaa atataggtat tttagtacag tacatacttg 2200

 cattacatag gtacttcaag caacacaata aaaagtaaat gataaagtga 2250

 acttgcttgt ttatagtaat aaacaagacc ataagagaat aagtatagct 2300

 agagaaattg cttctctgaa atgtacatga gcccttaagg taagagatga 2350

 tttccatcta ctctcatttt gattacttcc ttatggtttg agaggctaga 2400

 aactgagcct ctctactttt ggaaaaatga acatgtgagg tcagattttt 2450

 tttttttttt aagtcagcac tgatgccacc ctctcagtgg tcatttctga 2500

 gcatcttcct gacttgaaca ccttctacag caaactcttg caagtccagt 2550

 ttcatccctg taaggcaaat gtcttttcac gcagaaagtg ccatatagac 2600

 gagataaagg cagctaaaac gagggcagta gagagcactt acccgacccc 2650

 aaggtgccag agatgccctg aggatggtgg ttaaggaaac aggagcagga 2700

 aatgtacaca cagattcctg tccctttgcc aactactcct tccccatcaa 2750

 agaaaaacac ttgcacacag taactaccag ctccttctct caaacttgta 2800

 tttctcctgg aaatgtatct cagaaatgac ctcctctccc aaccacttca 2850

 acgattcttt ctttgggttt ggggttcttg cagttctatc atctaaaata 2900

 acctttggac tgcaggtaaa atgcaattag gacaactaac caagtagacg 2950

 aaacaagttc ccctaggcag gggtgtccaa tattttagct tccctggacc 3000

 gcattggaag aattttcttg ggccacatgt aaaacacact aacactaacc 3050

 atagttgatg agcttaaaaa aataaaaata gaaaattgc 3089

<210> 1975
<211> 225
<212> PRT
<213> Homo sapien

<400> 1975
 Met Ile Ser Pro Pro Leu Gly Asp Phe Arg His Thr Ile His Ile
   1               5                  10                  15

 Gly Lys Glu Gly Gln His Asp Val Phe Gly Asp Ile Ser Phe Leu
                  20                  25                  30

 Gln Gly Asn Tyr Glu Leu Leu Pro Gly Asn Gln Glu Lys Ala His
                  35                  40                  45

 Leu Gly Gln Phe Pro Gly His Asn Glu Phe Phe Arg Ala Asn Ser
                  50                  55                  60

 Thr Ser Asp Ser Val Phe Thr Glu Thr Pro Ser Pro Val Leu Lys
                  65                  70                  75

 Asn Ala Ile Ser Leu Pro Thr Ile Gly Gly Ser Gln Ala Leu Met
                  80                  85                  90

 Leu Pro Leu Leu Ser Pro Val Thr Phe Asn Ser Lys Gln Glu Ser
                  95                 100                 105

 Phe Gly Pro Ala Lys Leu Pro Arg Leu Ser Cys Glu Pro Val Met
                 110                 115                 120

 Glu Glu Lys Ala Gln Glu Lys Ser Ser Leu Leu Glu Asn Gly Thr
                 125                 130                 135

 Val His Gln Gly Asp Thr Ser Trp Gly Ser Ser Gly Ser Ala Ser
                 140                 145                 150

 Gln Ser Ser Gln Gly Arg Asp Ser His Ser Ser Ser Leu Ser Glu
                 155                 160                 165

 Gln Tyr Pro Asp Trp Pro Ala Glu Asp Met Phe Asp His Pro Thr
                 170                 175                 180

 Pro Cys Glu Leu Ile Lys Gly Lys Thr Lys Ser Glu Glu Ser Leu
                 185                 190                 195

 Ser Asp Leu Thr Gly Ser Leu Leu Ser Leu Gln Leu Asp Leu Gly
                 200                 205                 210

 Pro Ser Leu Leu Asp Glu Val Leu Asn Val Met Asp Lys Asn Lys
                 215                 220                 225

<210> 1976
<211> 3981
<212> DNA
<213> Homo sapien

<400> 1976
 cgggctgaga gggacctggg gagctgcggc ctggccgggg cggcgcactc 50

 aggtggcctc gcttccctgc gggtcaccgc ccgccactcg cacagctagg 100

 tcggcctgtt gggatcggga gaggtgggcg cacgagtttt agtgcgggag 150

 tccggggtgc gggcggagtc ctattgtccc cgtgcacccg ggcggcagca 200

 cctccgggtc cctctttaaa ccgagcgtcc ggcgaccttt ctttgtgctt 250

 agggagtcga aagcggcatc ttctccgaga gaagtcgcct actggggggt 300

 ggcgctgggg aggtaacaat gggcgcccat tgtcctccga gggtccaacg 350

 gtgacccccc cccgcgcgcg cgcccggcca ccggttggcc ccgggccagg 400

 gcacaggtac cgcggctggg agggtcggcc ccgctgcccg cgccctccgc 450

 cccgccccag tgagtccccg cgccgccggc cccgccccgc gccgccccgc 500

 cctccgcagg ttcagtcctc gcgtccggcc gccccgcgct cagtcgcgcg 550

 caccttctct cgcggccggg ggaccgcagc gcggggctag cccggagacc 600

 cggccaccgg cctggggcgc cttcacgccg tctcggagcg gataatgcgg 650

 tgagcaggca ccacgccggc agactcggct ggatctgcgc acagcggcag 700

 ggattgcgtg cgcccgcggg aggcccgggg cagcggctgg gatcctcagc 750

 ggcggccggt ttgtcctggt tgtggtcaag actggatgat gtaactggct 800

 ctctaggaag cctcacttgg ccgtaacctc aggaaggttc tctttgaccc 850

 catctcattt cgaagccact tctgaagcca cttgagaaaa atgatgtgac 900

 agttcctatc aaaaaggatt cagaaacata taccatctgt gaagaaagtg 950

 gccctttctc ccgcttgcaa aatagacatt ctcaaattcc aaaatgccag 1000

 ccaagacccc aatttacctg aaagcagcca ataacaagaa aggaaagaaa 1050

 tttaaactga gggacattct gtctcctgat atgatcagtc ccccgcttgg 1100

 agactttcgc cacaccatcc acattggcaa agagggccag cacgatgtct 1150

 ttggagatat ttcctttctt caagggaact acgagctttt acctggaaac 1200

 caggagaaag cacacctggg ccagttccct gggcataatg agttcttccg 1250

 ggccaacagc acctcggact ctgtgttcac agaaacgccc tccccggtgc 1300

 tcaaaaatgc catctccctc ccgaccattg gaggatccca agctctcatg 1350

 ttgcccttat tgtcaccagt gacatttaat tccaaacagg agtccttcgg 1400

 gccagcaaag ctgcccaggc ttagctgcga gcccgtcatg gaggaaaaag 1450

 ctcaggagaa aagcagtctg ttggagaatg ggacagtcca ccagggagac 1500

 acctcgtggg gctccagcgg ttctgcatct cagtccagcc aaggcagaga 1550

 cagccactcc tccagcctgt ccgaacagta ccccgactgg ccagccgagg 1600

 acatgtttga ccatcccacc ccatgcgagc tcatcaaggg aaagactaag 1650

 tcagaggagt ccctctctga ccttacaggt tccctcctct ccctgcagct 1700

 tgatcttggg ccctcacttt tggatgaggt gctgaatgta atggataaaa 1750

 ataagtaaca agatgccaac ttttttcctt tggggtaaaa ggtacaaaaa 1800

 caaactaacc acagttgaag agaagggctt ccggagctgt atttgcagtt 1850

 ttgtgttggg ttttctaaaa taatattctt acaaagtatt tttttacctg 1900

 ttatgccctg tttgcaaaaa caatttagaa aaaaacaaca aagcaaaacc 1950

 tatcttggca aaaaaaggaa gtgagtcaga gcccattttc aggaggcatt 2000

 ggtgatgttc ggctcacata ttgtttgcag acacacaaga aatctggctt 2050

 ggccaggatt ggcactagct atgaagggct gagcgagtca cattaaggaa 2100

 cttcacggaa ctttatagca ctccgacatt ttctgagcaa gaggaagtca 2150

 aaatttattt aacacctaag cctttttgta gactcttttc tatatattgc 2200

 ttaggctcac catagcgaat tctccagtgt taaaactttt ctgttttcac 2250

 atttgaactt tatgggtttt ggggattttc ttgtagttct tatatatccc 2300

 tatatattat atctatattg caaaattttg actgtcagct acatgttggt 2350

 aagacacagg caaagtatta ctgtaactaa gttattttta aagttaaaat 2400

 atatttttac gtgcctttgg ctttttattg cagagtctac attttataga 2450

 ttctacatca gatgttgtca cttatttcca ttgggattcc attgtaagct 2500

 gtgtatgtgc gtgtttggaa aagtgtattc atacttagtt tttttttctt 2550

 catctgttat catactttta acagcaacca ataacggatt gtaaagtgta 2600

 aaggcacagg ttactcatga tgcttctgca gagactgtgg gctacaccac 2650

 atatgttatt tggaaatata ggtattttag tacagtacat acttgcatta 2700

 cataggtact tcaagcaaca caataaaaag taaatgataa agtgaacttg 2750

 cttgtttata gtaataaaca agaccataag agaataagta tagctagaga 2800

 aattgcttct ctgaaatgta catgagccct taaggtaaga gatgatttcc 2850

 atctactctc attttgatta cttccttatg gtttgagagg ctagaaactg 2900

 agcctctcta cttttggaaa aatgaacatg tgaggtcaga tttttttttt 2950

 tttttttaag tcagcactga tgccaccctc tcagtggtca tttctgagca 3000

 tcttcctgac ttgaacacct tctacagcaa actcttgcaa gtccagtttc 3050

 atccctgtaa ggcaaatgtc ttttcacgca gaaagtgcca tatagacgag 3100

 ataaaggcag ctaaaacgag ggcagtagag agcacttacc cgaccccaag 3150

 gtgccagaga tgccctgagg atggtggtta aggaaacagg agcaggaaat 3200

 gtacacacag attcctgtcc ctttgccaac tactccttcc ccatcaaaga 3250

 aaaacacttg cacacagtaa ctaccagctc cttctctcaa acttgtattt 3300

 ctcctggaaa tgtatctcag aaatgacctc ctctcccaac cacttcaacg 3350

 attctttctt tgggtttggg gttcttgcag ttctatcatc taaaataacc 3400

 tttggactgc aggtaaaatg caattaggac aactaaccaa gtagacgaaa 3450

 caagttcccc taggcagggg tgtccaatat tttagcttcc ctggaccgca 3500

 ttggaagaat tttcttgggc cacatgtaaa acacactaac actaaccata 3550

 gttgatgagc ttaaaaaaat aaaaatagaa aattgcaaaa aaaaaaaaaa 3600

 aaaaaaatct cagactgttt taagaaagtt taaaaatttg tgttggactt 3650

 catgcgggcc acaggttgga caagcttgcc ctagggcatt gtgtgctttc 3700

 cgtaacttct cagttgtatt tcgttatcca tgactctcca gtgttttttc 3750

 tgttggacca cacccgtcac agttcacagt tccaaagaga aatttcccag 3800

 cctattctaa atcttgttaa tgacgaagag tccaatgtat ctcattattt 3850

 gtagccaatt ttagactctt ttcaatacct cccccccatt ttaattagta 3900

 ttgatcatat tcagtctttc attttactct tcatctgtag cgtgacctca 3950

 aggtaaagat gaaactattt catgaaaagg g 3981

<210> 1977
<211> 254
<212> PRT
<213> Homo sapien

<400> 1977
 Met Pro Ala Lys Thr Pro Ile Tyr Leu Lys Ala Ala Asn Asn Lys
   1               5                  10                  15

 Lys Gly Lys Lys Phe Lys Leu Arg Asp Ile Leu Ser Pro Asp Met
                  20                  25                  30

 Ile Ser Pro Pro Leu Gly Asp Phe Arg His Thr Ile His Ile Gly
                  35                  40                  45

 Lys Glu Gly Gln His Asp Val Phe Gly Asp Ile Ser Phe Leu Gln
                  50                  55                  60

 Gly Asn Tyr Glu Leu Leu Pro Gly Asn Gln Glu Lys Ala His Leu
                  65                  70                  75

 Gly Gln Phe Pro Gly His Asn Glu Phe Phe Arg Ala Asn Ser Thr
                  80                  85                  90

 Ser Asp Ser Val Phe Thr Glu Thr Pro Ser Pro Val Leu Lys Asn
                  95                 100                 105

 Ala Ile Ser Leu Pro Thr Ile Gly Gly Ser Gln Ala Leu Met Leu
                 110                 115                 120

 Pro Leu Leu Ser Pro Val Thr Phe Asn Ser Lys Gln Glu Ser Phe
                 125                 130                 135

 Gly Pro Ala Lys Leu Pro Arg Leu Ser Cys Glu Pro Val Met Glu
                 140                 145                 150

 Glu Lys Ala Gln Glu Lys Ser Ser Leu Leu Glu Asn Gly Thr Val
                 155                 160                 165

 His Gln Gly Asp Thr Ser Trp Gly Ser Ser Gly Ser Ala Ser Gln
                 170                 175                 180

 Ser Ser Gln Gly Arg Asp Ser His Ser Ser Ser Leu Ser Glu Gln
                 185                 190                 195

 Tyr Pro Asp Trp Pro Ala Glu Asp Met Phe Asp His Pro Thr Pro
                 200                 205                 210

 Cys Glu Leu Ile Lys Gly Lys Thr Lys Ser Glu Glu Ser Leu Ser
                 215                 220                 225

 Asp Leu Thr Gly Ser Leu Leu Ser Leu Gln Leu Asp Leu Gly Pro
                 230                 235                 240

 Ser Leu Leu Asp Glu Val Leu Asn Val Met Asp Lys Asn Lys
                 245                 250

<210> 1978
<211> 1378
<212> DNA
<213> Homo sapien

<400> 1978
 agcgtcggac taccgttggt ttccgcaact tcctggatta tcctcgccaa 50

 ggactttgca atatattttt ccgccttttc tggaaggatt tcgctgcttc 100

 ccgaagtctt ggacgagcgc tctagctctg tgggaaggtt ttgggctctc 150

 tggctcggat tttgcaattt ctccctgggg actgccgtgg agccgcatcc 200

 actgtggatt ataattgcaa catgacgctg gaagagctcg tggcgtgcga 250

 caacgcggcg cagaagatgc agacggtgac cgccgcggtg gaggagcttt 300

 tggtggccgc tcagcgccag gatcgcctca cagtgggggt gtacgagtcg 350

 gccaagttga tgaatgtgga cccagacagc gtggtcctct gcctcttggc 400

 cattgacgag gaggaggagg atgacatcgc cctgcaaatc cacttcacgc 450

 tcatccagtc cttctgctgt gacaacgaca tcaacatcgt gcgggtgtcg 500

 ggcatgcagc gcctggcgca gctcctggga gagccggccg agacccaggg 550

 caccaccgag gcccgagacc tgcattgtct cctggtcacg aaccctcaca 600

 cggacgcctg gaagagccac ggcttggtgg aggtggccag ctactgcgaa 650

 gaaagccggg gcaacaacca gtgggtcccc tacatctctc ttcaggaacg 700

 ctgaggccct tcccagcagc agaatctgtt gagttgctgc cacaaacaaa 750

 aaatacaata aatatttgaa ccccctcccc cccagcacaa cccccccaaa 800

 acaacccaac ccacgaggac catcgggggc agagtcgttg gagactgaag 850

 aggaagagga ggaggagaag gggagtgagc ggtccgcccc cagggacgct 900

 ctccaggagc tggcggccgc cgatcagatg gagaaggggg gacccaggcc 950

 agcaggagac aggacccccg aagctgaggc cttgggatgg agcagaagcc 1000

 ggagtggcgg ggcacgctgc cgccttcccc atcacggagg gtccagactg 1050

 tccactcggg ggtggagtga gactgactgc aagccccacc ctccttgaga 1100

 ctggagctgg cgtctgcata cgagagactt ggttgaactt ggttggtcct 1150

 tgtctgcacc ctcgacaaga ccacactttg ggacttggga gctggggctg 1200

 aagttgctct gtacccatga actcccagtt tgcgaattat agagacaatc 1250

 tattttgtta cttgcacttg ttattcgaac cactgagagc gagatgggaa 1300

 gcatagatat ctatattttt atttctacta tgagggcctt gtaataaatt 1350

 tctaaagcct ctgaaaaaaa aaaaaaaa 1378

<210> 1979
<211> 160
<212> PRT
<213> Homo sapien

<400> 1979
 Met Thr Leu Glu Glu Leu Val Ala Cys Asp Asn Ala Ala Gln Lys
   1               5                  10                  15

 Met Gln Thr Val Thr Ala Ala Val Glu Glu Leu Leu Val Ala Ala
                  20                  25                  30

 Gln Arg Gln Asp Arg Leu Thr Val Gly Val Tyr Glu Ser Ala Lys
                  35                  40                  45

 Leu Met Asn Val Asp Pro Asp Ser Val Val Leu Cys Leu Leu Ala
                  50                  55                  60

 Ile Asp Glu Glu Glu Glu Asp Asp Ile Ala Leu Gln Ile His Phe
                  65                  70                  75

 Thr Leu Ile Gln Ser Phe Cys Cys Asp Asn Asp Ile Asn Ile Val
                  80                  85                  90

 Arg Val Ser Gly Met Gln Arg Leu Ala Gln Leu Leu Gly Glu Pro
                  95                 100                 105

 Ala Glu Thr Gln Gly Thr Thr Glu Ala Arg Asp Leu His Cys Leu
                 110                 115                 120

 Leu Val Thr Asn Pro His Thr Asp Ala Trp Lys Ser His Gly Leu
                 125                 130                 135

 Val Glu Val Ala Ser Tyr Cys Glu Glu Ser Arg Gly Asn Asn Gln
                 140                 145                 150

 Trp Val Pro Tyr Ile Ser Leu Gln Glu Arg
                 155                 160

<210> 1980
<211> 817
<212> DNA
<213> Homo sapien

<400> 1980
 cggacgcgtg gggaaggatt tcgctgcttc ccgaaggtct tggacgagcg 50

 ctctagctct gtgggaaggt tttgggctct ctggctcgga ttttgcaatt 100

 tctccctggg gactgccgtg gagccgcatc cactgtggat tataattgca 150

 acatgacgct ggaagagctc gtggcgtgcg acaacgcggc gcagaagatg 200

 cagacggtga ccgccgcggt ggaggagctt ttggtggccg ctcagcgcca 250

 ggatcgcctc acagtggggg tgtacgagtc ggccaagttg atgaatgtgg 300

 acccagacag cgtggtcctc tgcctcttgg ccattgacga ggaggaggag 350

 gatgacatcg ccctgcaaat ccacttcacg ctcatccagt ccttctgctg 400

 tgacaacgac atcaacatcg tgcgggtgtc gggcatgcag cgcctggcgc 450

 agctcctggg agagccggcc gagacccagg gcaccaccga ggcccgagac 500

 ctgcattgtc tcctggtcac gaaccctcac acggacgcct ggaagagcca 550

 cggcttggtg gaggtggcca gctactgcga agaaagccgg ggcaacaacc 600

 agtgggtccc ctacatctct cttcaggaac gctgaggccc ttcccagcag 650

 cagaatctgt tgagttgctg ccacaaacaa aaaatacaat aaatatttga 700

 accccctccc ccccagcaca acccccccaa aacaacccaa cccacgagga 750

 ccatcggggg cagagtcgtt ggagactgaa gaggaagagg aggaggagaa 800

 ggggagtgag cggccgc 817

<210> 1981
<211> 114
<212> PRT
<213> Homo sapien

<400> 1981
 Met Asn Val Asp Pro Asp Ser Val Val Leu Cys Leu Leu Ala Ile
   1               5                  10                  15

 Asp Glu Glu Glu Glu Asp Asp Ile Ala Leu Gln Ile His Phe Thr
                  20                  25                  30

 Leu Ile Gln Ser Phe Cys Cys Asp Asn Asp Ile Asn Ile Val Arg
                  35                  40                  45

 Val Ser Gly Met Gln Arg Leu Ala Gln Leu Leu Gly Glu Pro Ala
                  50                  55                  60

 Glu Thr Gln Gly Thr Thr Glu Ala Arg Asp Leu His Cys Leu Leu
                  65                  70                  75

 Val Thr Asn Pro His Thr Asp Ala Trp Lys Ser His Gly Leu Val
                  80                  85                  90

 Glu Val Ala Ser Tyr Cys Glu Glu Ser Arg Gly Asn Asn Gln Trp
                  95                 100                 105

 Val Pro Tyr Ile Ser Leu Gln Glu Arg
                 110

<210> 1982
<211> 1286
<212> DNA
<213> Homo sapien

<400> 1982
 gctctttcca acgctgtaaa aaaggacaga ggctgttccc tatggcagaa 50

 ggcaaccaca gaaaaaagcc acttaaggtg ttggaatccc tgggcaaaga 100

 tttcctcact ggtgttttgg ataacttggt ggaacaaaat gtactgaact 150

 ggaaggaaga ggaaaaaaag aaatattacg atgctaaaac tgaagacaaa 200

 gttcgggtca tggcagactc tatgcaagag aagcaacgta tggcaggaca 250

 aatgcttctt caaacctttt ttaacataga ccaaatatcc cccaataaaa 300

 aagctcatcc gaatatggag gctggaccac ctgagtcagg agaatctaca 350

 gatgccctca agctttgtcc tcatgaagaa ttcctgagac tatgtaaaga 400

 aagagctgaa gagatctatc caataaagga gagaaacaac cgcacacgcc 450

 tggctctcat catatgcaat acagagtttg accatctgcc tccgaggaat 500

 ggagctgact ttgacatcac agggatgaag gagctacttg agggtctgga 550

 ctatagtgta gatgtagaag agaatctgac agccagggat atggagtcag 600

 cgctgagggc atttgctacc agaccagagc acaagtcctc tgacagcaca 650

 ttcttggtac tcatgtctca tggcatcctg gagggaatct gcggaactgt 700

 gcatgatgag aaaaaaccag atgtgctgct ttatgacacc atcttccaga 750

 tattcaacaa ccgcaactgc ctcagtctga aggacaaacc caaggtcatc 800

 attgtccagg cctgcagagg tgcaaaccgt ggggaactgt gggtcagaga 850

 ctctccagca tccttggaag tggcctcttc acagtcatct gagaacctgg 900

 aggaagatgc tgtttacaag acccacgtgg agaaggactt cattgctttc 950

 tgctcttcaa cgccacacaa cgtgtcctgg agagacagca caatgggctc 1000

 tatcttcatc acacaactca tcacatgctt ccagaaatat tcttggtgct 1050

 gccacctaga ggaagtattt cggaaggtac agcaatcatt tgaaactcca 1100

 agggccaaag ctcaaatgcc caccatagaa cgactgtcca tgacaagata 1150

 tttctacctc tttcctggca attgaaaatg gaagccacaa gcagcccagc 1200

 cctccttaat caacttcaag gagcaccttc attagtacag cttgcatatt 1250

 taacattttg tatttcaata aaagtgaaga caaacg 1286

<210> 1983
<211> 377
<212> PRT
<213> Homo sapien

<400> 1983
 Met Ala Glu Gly Asn His Arg Lys Lys Pro Leu Lys Val Leu Glu
   1               5                  10                  15

 Ser Leu Gly Lys Asp Phe Leu Thr Gly Val Leu Asp Asn Leu Val
                  20                  25                  30

 Glu Gln Asn Val Leu Asn Trp Lys Glu Glu Glu Lys Lys Lys Tyr
                  35                  40                  45

 Tyr Asp Ala Lys Thr Glu Asp Lys Val Arg Val Met Ala Asp Ser
                  50                  55                  60

 Met Gln Glu Lys Gln Arg Met Ala Gly Gln Met Leu Leu Gln Thr
                  65                  70                  75

 Phe Phe Asn Ile Asp Gln Ile Ser Pro Asn Lys Lys Ala His Pro
                  80                  85                  90

 Asn Met Glu Ala Gly Pro Pro Glu Ser Gly Glu Ser Thr Asp Ala
                  95                 100                 105

 Leu Lys Leu Cys Pro His Glu Glu Phe Leu Arg Leu Cys Lys Glu
                 110                 115                 120

 Arg Ala Glu Glu Ile Tyr Pro Ile Lys Glu Arg Asn Asn Arg Thr
                 125                 130                 135

 Arg Leu Ala Leu Ile Ile Cys Asn Thr Glu Phe Asp His Leu Pro
                 140                 145                 150

 Pro Arg Asn Gly Ala Asp Phe Asp Ile Thr Gly Met Lys Glu Leu
                 155                 160                 165

 Leu Glu Gly Leu Asp Tyr Ser Val Asp Val Glu Glu Asn Leu Thr
                 170                 175                 180

 Ala Arg Asp Met Glu Ser Ala Leu Arg Ala Phe Ala Thr Arg Pro
                 185                 190                 195

 Glu His Lys Ser Ser Asp Ser Thr Phe Leu Val Leu Met Ser His
                 200                 205                 210

 Gly Ile Leu Glu Gly Ile Cys Gly Thr Val His Asp Glu Lys Lys
                 215                 220                 225

 Pro Asp Val Leu Leu Tyr Asp Thr Ile Phe Gln Ile Phe Asn Asn
                 230                 235                 240

 Arg Asn Cys Leu Ser Leu Lys Asp Lys Pro Lys Val Ile Ile Val
                 245                 250                 255

 Gln Ala Cys Arg Gly Ala Asn Arg Gly Glu Leu Trp Val Arg Asp
                 260                 265                 270

 Ser Pro Ala Ser Leu Glu Val Ala Ser Ser Gln Ser Ser Glu Asn
                 275                 280                 285

 Leu Glu Glu Asp Ala Val Tyr Lys Thr His Val Glu Lys Asp Phe
                 290                 295                 300

 Ile Ala Phe Cys Ser Ser Thr Pro His Asn Val Ser Trp Arg Asp
                 305                 310                 315

 Ser Thr Met Gly Ser Ile Phe Ile Thr Gln Leu Ile Thr Cys Phe
                 320                 325                 330

 Gln Lys Tyr Ser Trp Cys Cys His Leu Glu Glu Val Phe Arg Lys
                 335                 340                 345

 Val Gln Gln Ser Phe Glu Thr Pro Arg Ala Lys Ala Gln Met Pro
                 350                 355                 360

 Thr Ile Glu Arg Leu Ser Met Thr Arg Tyr Phe Tyr Leu Phe Pro
                 365                 370                 375

 Gly Asn


<210> 1984
<211> 853
<212> DNA
<213> Homo sapien

<400> 1984
 gcctgctgct ctggcccctg gtcctgtcct gttctccagc atggtgtgtc 50

 tgaggctccc tggaggctcc tgcatggcag ttctgacagt gacactgatg 100

 gtgctgagct ccccactggc tttggctggg gacaccagac cacgtttctt 150

 ggagtactct acgtctgagt gtcatttctt caatgggacg gagcgggtgc 200

 ggtacctgga cagatacttc cataaccagg aggagaacgt gcgcttcgac 250

 agcgacgtgg gggagttccg ggcggtgacg gagctggggc ggcctgctgc 300

 ggagcactgg aacagccaga aggacctcct ggagcagaag cggggccggg 350

 tggacaacta ctgcagacac aactacgggg ttgtggagag cttcacagtg 400

 cagcggcgag tccatcctaa ggtgactgtg tatccttcaa agacccagcc 450

 cctgcagcac cataacctcc tggtctgttc tgtgagtggt ttctatccag 500

 gcagcattga agtcaggtgg ttccggaatg gccaggaaga gaagactggg 550

 gtggtgtcca caggcctgat ccacaatgga gactggacct tccagaccct 600

 ggtgatgctg gaaacagttc ctcggagtgg agaggtttac acctgccaag 650

 tggagcaccc aagcgtgaca agccctctca cagtggaatg gagagcacgg 700

 tctgaatctg cacagagcaa gatgctgagt ggagtcgggg gctttgtgct 750

 gggcctgctc ttccttgggg ccgggctgtt catctacttc aggaatcaga 800

 aaggacactc tggacttcag ccaagaggat tcctgagctg aagtgcagat 850

 gac 853

<210> 1985
<211> 266
<212> PRT
<213> Homo sapien

<400> 1985
 Met Val Cys Leu Arg Leu Pro Gly Gly Ser Cys Met Ala Val Leu
   1               5                  10                  15

 Thr Val Thr Leu Met Val Leu Ser Ser Pro Leu Ala Leu Ala Gly
                  20                  25                  30

 Asp Thr Arg Pro Arg Phe Leu Glu Tyr Ser Thr Ser Glu Cys His
                  35                  40                  45

 Phe Phe Asn Gly Thr Glu Arg Val Arg Tyr Leu Asp Arg Tyr Phe
                  50                  55                  60

 His Asn Gln Glu Glu Asn Val Arg Phe Asp Ser Asp Val Gly Glu
                  65                  70                  75

 Phe Arg Ala Val Thr Glu Leu Gly Arg Pro Ala Ala Glu His Trp
                  80                  85                  90

 Asn Ser Gln Lys Asp Leu Leu Glu Gln Lys Arg Gly Arg Val Asp
                  95                 100                 105

 Asn Tyr Cys Arg His Asn Tyr Gly Val Val Glu Ser Phe Thr Val
                 110                 115                 120

 Gln Arg Arg Val His Pro Lys Val Thr Val Tyr Pro Ser Lys Thr
                 125                 130                 135

 Gln Pro Leu Gln His His Asn Leu Leu Val Cys Ser Val Ser Gly
                 140                 145                 150

 Phe Tyr Pro Gly Ser Ile Glu Val Arg Trp Phe Arg Asn Gly Gln
                 155                 160                 165

 Glu Glu Lys Thr Gly Val Val Ser Thr Gly Leu Ile His Asn Gly
                 170                 175                 180

 Asp Trp Thr Phe Gln Thr Leu Val Met Leu Glu Thr Val Pro Arg
                 185                 190                 195

 Ser Gly Glu Val Tyr Thr Cys Gln Val Glu His Pro Ser Val Thr
                 200                 205                 210

 Ser Pro Leu Thr Val Glu Trp Arg Ala Arg Ser Glu Ser Ala Gln
                 215                 220                 225

 Ser Lys Met Leu Ser Gly Val Gly Gly Phe Val Leu Gly Leu Leu
                 230                 235                 240

 Phe Leu Gly Ala Gly Leu Phe Ile Tyr Phe Arg Asn Gln Lys Gly
                 245                 250                 255

 His Ser Gly Leu Gln Pro Arg Gly Phe Leu Ser
                 260                 265

<210> 1986
<211> 7163
<212> DNA
<213> Homo sapien

<400> 1986
 tgaccctgag gcattgccgt cgcgcggtgc acagctaaga cgtcgcgctt 50

 gcgcaggcgc tcggcgcaga ggcctgcggg aagccaagat ggcgcatagg 100

 ggttctccag gctgcagttg gcgccttatc agtatctaag cggagtgttt 150

 tggaaggagt taaggggctg tggcaaacgc cctctccgcc gtcatggccc 200

 ggcatcggaa tgttcgaggc tataactacg atgaagattt tgaagatgat 250

 gatctctacg gccagtctgt agaggatgat tattgtattt cgccgtcaac 300

 agctgctcag tttatttatt cacggcgtga caaaccttcc gttgagcctg 350

 tggaagaata tgattatgaa gatctgaaag aatcttccaa ttctgtttca 400

 aaccatcagc tcagtggatt tgatcaagct cgtctttatt catgccttga 450

 tcacatgaga gaggtacttg gagatgctgt gccagatgaa atattaattg 500

 aagcagttct gaagaacaag tttgatgtgc agaaggcttt gtcaggggtt 550

 ctggaacaag atagagtgca gagtttgaag gacaagaatg aggcaacagt 600

 atctacagga aagatagcaa aaggaaaacc agtagattcc cagacatcgc 650

 gaagtgaatc tgaaattgtg ccaaaagttg ctaaaatgac tgtatctgga 700

 aagaagcaaa ctatgggatt tgaagtgcct ggagtatctt ctgaagaaaa 750

 tggtcatagt ttccacacac ctcaaaaagg accgcccatt gaagatgcca 800

 ttgcttcttc cgatgttctt gagactgctt ctaaatctgc taatccaccc 850

 cacacgattc aagcatcaga agagcagagt tcaaccccag caccggtgaa 900

 aaagtctggc aagctgaggc agcaaataga tgtgaaggcg gaactggaga 950

 agcggcaagg agggaagcag ctactcaact tagtggtcat tggtcatgtt 1000

 gatgctggga aaagtactct gatgggccat atgctttatc ttctgggtaa 1050

 tataaacaaa agaactatgc ataagtatga acaggagtct aaaaaggctg 1100

 gcaaagcttc gtttgcatat gcatgggtct tggatgaaac tggcgaagaa 1150

 agggaaaggg gagtaaccat ggatgttggt atgacaaagt ttgaaaccac 1200

 aaccaaagtt attacattaa tggatgctcc aggccataag gacttcattc 1250

 caaatatgat tacaggagca gcccaggcgg atgtagctgt tttagttgta 1300

 gatgccagca ggggagagtt tgaagctgga tttgagactg gaggacaaac 1350

 acgagagcat ggactcttgg tccgttctct gggagtgacg cagcttgcag 1400

 ttgcagttaa taaaatggat caggttaatt ggcaacaaga aaggtttcaa 1450

 gagattactg gaaaacttgg gcactttctt aagcaagcag gttttaagga 1500

 gagtgatgta ggttttattc ctacaagtgg tctcagtggt gaaaatctaa 1550

 tcacaagatc tcagtcaagt gaactcacaa aatggtataa aggactatgt 1600

 ttattagaac aaattgattc ctttaagcct ccccagcgat ctattgacaa 1650

 accttttaga ttatgtgtgt ccgatgtttt caaagatcaa ggatctggat 1700

 tttgcataac tggtaaaata gaagctggtt atatccaaac tggtgaccga 1750

 ctactggcaa tgcctcctaa tgaaacttgt accgtgaaag gaatcactct 1800

 gcatgatgaa cctgtcgact gggcggcagc aggcgatcat gttagtctta 1850

 ctttggttgg gatggatatc atcaaaatca atgttggctg catattttgt 1900

 ggccccaaag tacccattaa agcttgcact cgtttcagag cccgaatcct 1950

 catctttaat attgaaattc ctatcactaa aggatttcct gtgctgttac 2000

 actaccaaac tgtcagtgaa cccgccgtta ttaaacgatt gattagtgtc 2050

 ttaaacaaaa gcacgggtga agtcacaaag aaaaagccta agtttttgac 2100

 taaaggccag aatgcattgg tagagctaca gacacaaaga ccaatagctc 2150

 ttgagctata taaagacttt aaagagctgg ggaggttcat gctacgttac 2200

 ggtggttcta caatagctgc tggtgttgtc actgagataa aagaatgatg 2250

 ggtcagaatt tctaccacgt ttctggatac agtgaaatag ctaacctctg 2300

 tttcaagaat gcagttatta agtcaaagga acaatgtgca attgatatgt 2350

 ttttagatga gagagaaaaa ttaaagctaa aattagctgc aaagaagtat 2400

 taataatcac ctctgcaaaa attctaagtt gccaactggc aaagaaagtc 2450

 taatgttaaa aacaactttg cctttgaaac gttaataaat ggatttactt 2500

 tgctaagatt tatggcaagt gtcaaaaata gtatctgaag atactgaatc 2550

 atcatgaaat gaactctact tctggccaaa gcacaatgta tttgcagttt 2600

 tctcttttga ttcaattata ctgcacatgt tttaaggaaa agtaacttaa 2650

 ttgggttttt caggcagttg atatttgacc taagcttttt tttttttttt 2700

 tttttccagt taatgctaag aaaagatttg gggaaggtta taataaaagt 2750

 attttgtggt gaccataaga atgtccctcc ccaaaacaag taaacttgtg 2800

 aaagtttaat ttggaattag tggaagctgt tcctttgaaa gccaagatat 2850

 tatttaagtt gtaaagccag ctaataaaat gccttagttt gagcataata 2900

 caaactgtgt tttgttcttt agacatttat gagattctct gccactaaca 2950

 gtaaatatga tttaggggtt ttgtgggatc tttttcacct aagagtttcc 3000

 tagctctgtc acatgaattc ttttttatcc taatggcaga tccaatttca 3050

 tctcattcat ttttttaacc ataacttgct tttcccattc tcacttttag 3100

 aattatacct atgatggccc tttctttatc ttgcttacct tatagattat 3150

 aagtcccctg tgagtaagta agagtcatgt ttttctttaa agtttcaaca 3200

 acaaacccca aggtttattt atttaacaac aggtattcgt tgaggtgcct 3250

 tctgggtgca aggagcttta gagtagattt tgacctcagc tgaacctgga 3300

 actctgatct gatagactgt ttatgataag cttttttttt tattagcagc 3350

 gtgatttgta tatcgatggc ttaacatata caacagcatt tcttctccct 3400

 gcaccttttc gtgaacctga cattttgaac ataagcaata acatctgtat 3450

 ggtaaagtag gcagattata catgtgttgc ttagtgaatg attaccaagt 3500

 gaacacactt ggtatattgc tttaccaaaa tacatgtgta gttgtcactt 3550

 cagattcact gagttaagaa agttttattt aaatattaat attaatcaag 3600

 aatttaacag atatatgtga cagaaatcta acttcaagtg actgaagcag 3650

 aaagaaaaat ttttgaatga cataactgag aaaattagag gtagctctag 3700

 ctttgattcc atttagatcg agcagctcac acaatgttag caaggactca 3750

 tctccactct gccttccctg gtgctggttt tgctctcaaa ctctatatag 3800

 aactctcggc cgggcgcggt ggctcacacc tgtaatcaaa acactttggg 3850

 aggctgagtc gggaggatag cgtgagccca ggagtttgag accagctaag 3900

 gcaatatagt gagaccatgt ctctacagaa aaaatttaaa aacagatcag 3950

 ctgggtgtgg tgccacatgc ctgtagtccc agcttctcag gaggctgggg 4000

 tgggaagatc acttgagccc aggaggtcga ggctgcagtg agccatgatc 4050

 acatcactgc agtccagcct gggtgacaga gcaagacctg tcaccctgcc 4100

 acccataaaa aacctcttct gtaatgccag gttcttgaca agatgtgata 4150

 attccacact tacatcctca gatctcccat ccagggcaag gacagactaa 4200

 aagagcatat cttctccaga agtcctagaa acatctcatc attgactatg 4250

 attgaatttt atttattaat acttccctag gatatcctgt gtttgagtgt 4300

 gaagttaata tcacacaaag catgtagcta acagttgtgt gagggttgga 4350

 aattcagggt gctgttagga aggggaaatg gattggggtt taaggtaggg 4400

 ggagtaaaaa caagaaacca tccactctgt atattatata agactgtgat 4450

 cgaattaaga attttagttt acagtttagc ataaacaaat agtagtagaa 4500

 atgaatgcat ttattcattc cttccttctc caatagtgtt taagtacaat 4550

 ctttttattt gcattttatt gatgattgat tgtggttgaa aggagtggtg 4600

 atattatttc gaggatccac tgtgtaagaa gactgttggc agtggaaggc 4650

 tcgagttgat taagtgacaa agaggtaaag cagacatgcc caagcttggt 4700

 tatgctctga tttcctaccc tgttactttc atccataatt tatagtacat 4750

 ccattttgtg tcattttgct tcaggtattt cttgtcctga ctgtcttctt 4800

 ttttatgatt ttactgtttc ttcacactaa tggctttgtc ctctgacttt 4850

 gactctttgt gagattcttc tgagcagtta acctctagga taatgtggct 4900

 tgaacacatt acagaactat gttttgactt gttagtatta ttcacacatt 4950

 catgacaatt gagcctctct actgtgagaa atgttttaga ggccagtttc 5000

 taggcatagc tgtttttctc ccatgagtat gcaaatcaat agttttaacc 5050

 attgttaaaa tgcaatcata gtgacttcag aaaatttgga aaatacagaa 5100

 aatataggga agaataaaat taacccacag ttctgtcacc taaaggtaac 5150

 tgctgccaat gttttcatgt atttcttttc tgtctctcca atgcattttt 5200

 ttacatagtt gtgagcgtta gccaagttat tttcatgttg ttatgtaatc 5250

 aatatttttc aatagaagta ttagaggttt tttttattga tataaaaata 5300

 acaattacag atcctgatat atagaagtta ttcaaaatta tacagttttc 5350

 aaaaaatcaa gacaagtagg cccaatacaa actactgaat catcttctaa 5400

 tttccctcta aaatatttat agaaatatgt aagtagaaaa acattcatcc 5450

 tttcctcgtc taattatgat cctgccatat tccaggcaca agagaaagct 5500

 ctggggcttg agtcttaata gggctgatag tccaaccagg ggacagggta 5550

 tcataaagag ataattcaaa actttaagat tggagggtag gtgatggtag 5600

 aaaattctgc ggcaaacatt tgttgatgct catcatttgt tgatgtcatc 5650

 aaagatcacc agggcataat tataatcaaa attagtttta ttgatgcttg 5700

 ctgcagcaag agagactgca caccactggg gtctatgggt gcttctcagt 5750

 gggaaggtgt aaggaggggc ttgctaagaa tttgagcaca tgtagctaat 5800

 tttaaggagg gctcaagtga gcaagggttt cttctggatt gagtgctgtc 5850

 agaaagtgga ttgagtgctg tcagaaagtg ggagtgattt tgcaactggg 5900

 tatcttaatt tttatgttgt gggtgggagg aaaggaaaga agcaacagtc 5950

 acccatgtta gccacaagaa gaggttggct gtttatggtt tgcacagtga 6000

 ctttgttttt atctgtgctc aggcatgatt acagtatctc attttatccg 6050

 gattacagtg acctcatctg atgttagaga tttgagaatt gttaaatgtt 6100

 cagcaggaga acgccaccgc ctagtgtgaa tgctaggtca gaagctgctt 6150

 tttcacactg aaaccattta agtatgtaca aataagttaa tagtgtaaat 6200

 gtaggtgtaa aatacaatgc aaaacaaaat aatgaagtaa gtgaattaaa 6250

 ttattgcacc aaatatgggg atatgaaata gggaaagaaa agcattaagt 6300

 tacttatagt ccataaaggg actacattat tttgttactc tgataatccc 6350

 ataaaacaaa gttttaagaa tgtttacagt aaccatgaat ggaattagtg 6400

 aaactattca tatcaatgca aaaaaaaaaa aaaaaaaaag caaagaaact 6450

 aagtctgtac agcaaaagat ggtaaggaaa caagaaaatt aaatgaagac 6500

 aaaggttgtg attattacag taaatgaaaa taggttttta tctttaaaat 6550

 gtagactcaa actgcaaagc taatgatatg ctatctgcaa aatattccta 6600

 ttttgtaaat aaataaaacc atagatttaa agaagaaagg gcacagatgt 6650

 actggggaga caaaaataac tgatccgttg ggtgtatacc atgtgccaag 6700

 caattttcat atactcattt aacatgacat atctataatt atatgaggca 6750

 gatattatta acctcagtct atagatgaga agactaaagc tcagagggat 6800

 tgctaaaaac tagtaaataa attatggaac catgatttga atttagattt 6850

 aagtctgact gaggcatgtt caaagacact acactgcctc tccagaaatc 6900

 aggagtagca atattaacac tggacaaaga atttaaagca agtaaaaaaa 6950

 aattaagaga atttcatatt aataacaagt ataatgcaca ataaaactgt 7000

 accaaatgac ataaaaatgc ataatgaaat ttattagaaa ttaaaaatta 7050

 aagggcatag ttacaattat tgaggaattc tcatagctct gccttataga 7100

 tcatgtaaac aaacaaggtc atagaggact taaatagcaa agcagaaaaa 7150

 aaaaaaaaaa aaa 7163

<210> 1987
<211> 684
<212> PRT
<213> Homo sapien

<400> 1987
 Met Ala Arg His Arg Asn Val Arg Gly Tyr Asn Tyr Asp Glu Asp
   1               5                  10                  15

 Phe Glu Asp Asp Asp Leu Tyr Gly Gln Ser Val Glu Asp Asp Tyr
                  20                  25                  30

 Cys Ile Ser Pro Ser Thr Ala Ala Gln Phe Ile Tyr Ser Arg Arg
                  35                  40                  45

 Asp Lys Pro Ser Val Glu Pro Val Glu Glu Tyr Asp Tyr Glu Asp
                  50                  55                  60

 Leu Lys Glu Ser Ser Asn Ser Val Ser Asn His Gln Leu Ser Gly
                  65                  70                  75

 Phe Asp Gln Ala Arg Leu Tyr Ser Cys Leu Asp His Met Arg Glu
                  80                  85                  90

 Val Leu Gly Asp Ala Val Pro Asp Glu Ile Leu Ile Glu Ala Val
                  95                 100                 105

 Leu Lys Asn Lys Phe Asp Val Gln Lys Ala Leu Ser Gly Val Leu
                 110                 115                 120

 Glu Gln Asp Arg Val Gln Ser Leu Lys Asp Lys Asn Glu Ala Thr
                 125                 130                 135

 Val Ser Thr Gly Lys Ile Ala Lys Gly Lys Pro Val Asp Ser Gln
                 140                 145                 150

 Thr Ser Arg Ser Glu Ser Glu Ile Val Pro Lys Val Ala Lys Met
                 155                 160                 165

 Thr Val Ser Gly Lys Lys Gln Thr Met Gly Phe Glu Val Pro Gly
                 170                 175                 180

 Val Ser Ser Glu Glu Asn Gly His Ser Phe His Thr Pro Gln Lys
                 185                 190                 195

 Gly Pro Pro Ile Glu Asp Ala Ile Ala Ser Ser Asp Val Leu Glu
                 200                 205                 210

 Thr Ala Ser Lys Ser Ala Asn Pro Pro His Thr Ile Gln Ala Ser
                 215                 220                 225

 Glu Glu Gln Ser Ser Thr Pro Ala Pro Val Lys Lys Ser Gly Lys
                 230                 235                 240

 Leu Arg Gln Gln Ile Asp Val Lys Ala Glu Leu Glu Lys Arg Gln
                 245                 250                 255

 Gly Gly Lys Gln Leu Leu Asn Leu Val Val Ile Gly His Val Asp
                 260                 265                 270

 Ala Gly Lys Ser Thr Leu Met Gly His Met Leu Tyr Leu Leu Gly
                 275                 280                 285

 Asn Ile Asn Lys Arg Thr Met His Lys Tyr Glu Gln Glu Ser Lys
                 290                 295                 300

 Lys Ala Gly Lys Ala Ser Phe Ala Tyr Ala Trp Val Leu Asp Glu
                 305                 310                 315

 Thr Gly Glu Glu Arg Glu Arg Gly Val Thr Met Asp Val Gly Met
                 320                 325                 330

 Thr Lys Phe Glu Thr Thr Thr Lys Val Ile Thr Leu Met Asp Ala
                 335                 340                 345

 Pro Gly His Lys Asp Phe Ile Pro Asn Met Ile Thr Gly Ala Ala
                 350                 355                 360

 Gln Ala Asp Val Ala Val Leu Val Val Asp Ala Ser Arg Gly Glu
                 365                 370                 375

 Phe Glu Ala Gly Phe Glu Thr Gly Gly Gln Thr Arg Glu His Gly
                 380                 385                 390

 Leu Leu Val Arg Ser Leu Gly Val Thr Gln Leu Ala Val Ala Val
                 395                 400                 405

 Asn Lys Met Asp Gln Val Asn Trp Gln Gln Glu Arg Phe Gln Glu
                 410                 415                 420

 Ile Thr Gly Lys Leu Gly His Phe Leu Lys Gln Ala Gly Phe Lys
                 425                 430                 435

 Glu Ser Asp Val Gly Phe Ile Pro Thr Ser Gly Leu Ser Gly Glu
                 440                 445                 450

 Asn Leu Ile Thr Arg Ser Gln Ser Ser Glu Leu Thr Lys Trp Tyr
                 455                 460                 465

 Lys Gly Leu Cys Leu Leu Glu Gln Ile Asp Ser Phe Lys Pro Pro
                 470                 475                 480

 Gln Arg Ser Ile Asp Lys Pro Phe Arg Leu Cys Val Ser Asp Val
                 485                 490                 495

 Phe Lys Asp Gln Gly Ser Gly Phe Cys Ile Thr Gly Lys Ile Glu
                 500                 505                 510

 Ala Gly Tyr Ile Gln Thr Gly Asp Arg Leu Leu Ala Met Pro Pro
                 515                 520                 525

 Asn Glu Thr Cys Thr Val Lys Gly Ile Thr Leu His Asp Glu Pro
                 530                 535                 540

 Val Asp Trp Ala Ala Ala Gly Asp His Val Ser Leu Thr Leu Val
                 545                 550                 555

 Gly Met Asp Ile Ile Lys Ile Asn Val Gly Cys Ile Phe Cys Gly
                 560                 565                 570

 Pro Lys Val Pro Ile Lys Ala Cys Thr Arg Phe Arg Ala Arg Ile
                 575                 580                 585

 Leu Ile Phe Asn Ile Glu Ile Pro Ile Thr Lys Gly Phe Pro Val
                 590                 595                 600

 Leu Leu His Tyr Gln Thr Val Ser Glu Pro Ala Val Ile Lys Arg
                 605                 610                 615

 Leu Ile Ser Val Leu Asn Lys Ser Thr Gly Glu Val Thr Lys Lys
                 620                 625                 630

 Lys Pro Lys Phe Leu Thr Lys Gly Gln Asn Ala Leu Val Glu Leu
                 635                 640                 645

 Gln Thr Gln Arg Pro Ile Ala Leu Glu Leu Tyr Lys Asp Phe Lys
                 650                 655                 660

 Glu Leu Gly Arg Phe Met Leu Arg Tyr Gly Gly Ser Thr Ile Ala
                 665                 670                 675

 Ala Gly Val Val Thr Glu Ile Lys Glu
                 680

<210> 1988
<211> 2132
<212> DNA
<213> Homo sapien

<400> 1988
 gccatgtgcc gcaccctggc cgccttcccc accacctgcc tggagagagc 50

 caaagagttc aagacacgtc tggggatctt tcttcacaaa tcagagctgg 100

 gctgcgatac tgggagtact ggcaagttcg agtggggcag taaacacagc 150

 aaagagaata gaaacttctc agaagatgtg ctggggtgga gagagtcgtt 200

 cgacctgctg ctgagcagta aaaatggagt ggctgccttc cacgctttcc 250

 tgaagacaga gttcagtgag gagaacctgg agttctggct ggcctgtgag 300

 gagttcaaga agatccgatc agctaccaag ctggcctcca gggcacacca 350

 gatctttgag gagttcattt gcagtgaggc ccctaaagag gtcaacattg 400

 accatgagac ccgcgagctg acgaggatga acctgcagac tgccacagcc 450

 acatgctttg atgcggctca ggggaagaca cgtaccctga tggagaagga 500

 ctcctaccca cgcttcctga agtcgcctgc ttaccgggac ctggctgccc 550

 aagcctcagc cgcctctgcc actctgtcca gctgcagcct ggacgagccc 600

 tcacacacct gagtctccac ggcagtgagg aagccagccg ggaagagagg 650

 ttgagtcacc catccccgag gtggctgccc ctgtgtggga ggcaggttct 700

 gcaaagcaag tgcaagagga caaaaaaaaa aaaaaaaaaa aaaatgcgct 750

 ccagcagcct gtttgggaag cagcagtctc tccttcaaat actgtgggac 800

 tcatgctgga gaggagccgc ccacttccag gacctgtgaa taagggctaa 850

 tgatgagggt tggtggggct ctctgtgggg caaaaaggtg gtatgggggt 900

 tagcactggc tctcgttctc accggagaag gaagtgttct agtgtggttt 950

 aggaaacatg tggataaagg gaaccatgaa aatgagagga ggaaagacat 1000

 ccagatcagc tgttttgcct gttgctcagt tgactctgat tgcatcctgt 1050

 tttcctaatt cccagactgt tctgggcacg gaagggaccc tggatgtgga 1100

 gtcttcccct ttggccctcc tcactggcct ctgggctagc ccagagtccc 1150

 ttagcttgta cctcgtaaca ctcctgtgtg tctgtccagc cttgcagtca 1200

 tgtcaaggcc agcaagctga tgtgactctt gccccatgcg agatatttat 1250

 acctcaaaca ctggcctgtg agccctttcc aagtcagtgg agagccctga 1300

 aaggaggctc acttgaatcc agctcagtgc tctgggtggc cccctgcagg 1350

 tggcccctga ccctgcgttg cagcagggtc cacctgtgag caggcccgcc 1400

 ctggggcctc ttcctggatg tgccctctct gagttctgtg ctgtctcttg 1450

 gaggcagggc ccaggagaac aaagtgtgga ggcctcgggg agtggctttt 1500

 ccagctctca tgccccgcag tgtggaacaa ggcagaaaag gatcctagga 1550

 aataagtctc ttggcggtcc ctgagagtcc tgctgaaatc cagccagtgt 1600

 tttttgtggt atgagaacag gcaaaaagag atgccccgag atagaagggg 1650

 agccttgtgt ttctttcctg cagacgtgag atgaacactg gagtgggcag 1700

 aggtggccca ggaccatggc acccttagag tgcagaagct ggggggagag 1750

 gctgcttcga agggcaggac tggggataat cagaacctgc ctgtcacctc 1800

 agggcatcac tgaacaaaca tttcctgatg ggaactcctg cggcagagcc 1850

 caggctgggg aagtgaacta cccagggcag cccctttgtg gcccaggata 1900

 atcaacactg ttctctctgt accatgagct cctccaggag attatttaag 1950

 tgtattgtat cattggtttt ctgtgattgt cataacattg tttttgttat 2000

 tgttggtgct gttgttattt attattgtaa tttcagtttg cctctactgg 2050

 agaatctcag caggggtttc agcctgactg tctccctttc tctaccagac 2100

 tctacctctg aatgtgctgg gaacctcttg ga 2132

<210> 1989
<211> 202
<212> PRT
<213> Homo sapien

<400> 1989
 Met Cys Arg Thr Leu Ala Ala Phe Pro Thr Thr Cys Leu Glu Arg
   1               5                  10                  15

 Ala Lys Glu Phe Lys Thr Arg Leu Gly Ile Phe Leu His Lys Ser
                  20                  25                  30

 Glu Leu Gly Cys Asp Thr Gly Ser Thr Gly Lys Phe Glu Trp Gly
                  35                  40                  45

 Ser Lys His Ser Lys Glu Asn Arg Asn Phe Ser Glu Asp Val Leu
                  50                  55                  60

 Gly Trp Arg Glu Ser Phe Asp Leu Leu Leu Ser Ser Lys Asn Gly
                  65                  70                  75

 Val Ala Ala Phe His Ala Phe Leu Lys Thr Glu Phe Ser Glu Glu
                  80                  85                  90

 Asn Leu Glu Phe Trp Leu Ala Cys Glu Glu Phe Lys Lys Ile Arg
                  95                 100                 105

 Ser Ala Thr Lys Leu Ala Ser Arg Ala His Gln Ile Phe Glu Glu
                 110                 115                 120

 Phe Ile Cys Ser Glu Ala Pro Lys Glu Val Asn Ile Asp His Glu
                 125                 130                 135

 Thr Arg Glu Leu Thr Arg Met Asn Leu Gln Thr Ala Thr Ala Thr
                 140                 145                 150

 Cys Phe Asp Ala Ala Gln Gly Lys Thr Arg Thr Leu Met Glu Lys
                 155                 160                 165

 Asp Ser Tyr Pro Arg Phe Leu Lys Ser Pro Ala Tyr Arg Asp Leu
                 170                 175                 180

 Ala Ala Gln Ala Ser Ala Ala Ser Ala Thr Leu Ser Ser Cys Ser
                 185                 190                 195

 Leu Asp Glu Pro Ser His Thr
                 200

<210> 1990
<211> 3201
<212> DNA
<213> Homo sapien

<400> 1990
 ggatccgcgc ggcacacgtg cgacggccgt gatgaagttc gcttaccggt 50

 tttcaaattt gctgggtacg gtgtaccggc gtgggaacct aaattttacc 100

 tgcaatggaa attcagttat cagtcccgtg ggcaatagag tcactgtatt 150

 tgaccttaaa aacaacaaat ctgacacgct gcccctggcc actcggtaca 200

 acgtcaagtg cgtggggctg tccccggatg gccgcctcgc tatcatcgtc 250

 gatgaagggg gcgatgcgct gctggtcagc ctggtctgca ggtctgtgct 300

 gcaccacttc cacttcaagg gctctgtgca cagtgtgtcc ttctcccctg 350

 atggcaggaa gtttgttgtc acaaagggta acattgccca gatgtatcat 400

 gcccctggga agaagcggga gttcaacgcc ttcgttctgg acaagaccta 450

 ttttgggccc tacgatgaga ccacctgcat cgactggacg gatgactcca 500

 ggtgctttgt ggttgggagc aaagacatgt ccacctgggt gttcggagcc 550

 gagcgctggg acaacctcat ctactatgca ctggggggac ataaggatgc 600

 catcgtggcc tgcttctttg aatccaacag cctggacctg tactcactca 650

 gccaggacgg agtgctgtgc atgtggcagt gtgacacgcc ccccgagggc 700

 ttgcggctga agccccctgc gggctggaaa gcagacctgt tgcagcggga 750

 ggaggaagag gaggaggagg aggaccagga gggcgacaga gagaccacca 800

 tccggggaaa agccactccg gccgaggagg agaagacagg aaaagtgaag 850

 tactcacggc tggccaagta cttcttcaat aaagaagggg attttaacaa 900

 cctgacagct gcagcatttc ataagaagtc tcacctcttg gtcactggct 950

 ttgcttctgg aatcttccat cttcatgagc tgccagagtt taacctcatc 1000

 cactccctga gcatctcaga tcagagcatc gcctcagtgg ccatcaatag 1050

 ctcgggggac tggattgctt ttggctgttc aggcctgggc cagctgctgg 1100

 tgtgggagtg gcagagtgag tcctacgtgc tcaagcagca gggccacttc 1150

 aacagcatgg tggccctggc ctactcgccc gacggacagt acatcgtgac 1200

 tggcggggac gacggcaagg tcaaggtgtg gaataccctc agcggcttct 1250

 gcttcgtcac ttttacggag cactccagcg gggtgaccgg tgtgaccttt 1300

 actgccaccg gctacgttgt ggtgacctca tccatggacg ggaccgtgcg 1350

 agcctttgac cttcacaggt accgaaactt ccgcaccttc acctctccac 1400

 gccccaccca gttctcctgt gtggcggtgg atgcgagcgg tgagatcgtc 1450

 tctgcagggg cgcaggactc ctttgagatt ttcgtgtggt ccatgcagac 1500

 aggcaggctc cttgatgttt tgtctggaca cgaagggccc atcagtggtc 1550

 tgtgttttaa cccaatgaag tccgtcctgg ccagtgcctc ctgggacaag 1600

 acggtgcgcc tatgggacat gtttgacagc tggaggacca aggagacgct 1650

 ggccctgacc tctgatgctc tggctgtgac ttttcgccct gatggtgcgg 1700

 agctggctgt ggccacactg aactcacaga tcaccttctg ggaccctgag 1750

 aacgcggtgc agacgggctc cattgagggc aggcatgacc tcaagactgg 1800

 caggaaggag ctggacaaga ttacagccaa gcacgcggcc aaggggaagg 1850

 ccttcaccgc cctgtgctac tctgcagacg gccacagcat cctggcggga 1900

 ggcatgtcca agttcgtgtg catctaccac gtccgtgagc agattctcat 1950

 gaagaggttc gagatctctt gcaacctgtc tctggacgcc atggaggaat 2000

 ttttgaaccg aagaaaaatg acagagtttg gcaacctggc actaattgat 2050

 caggatgctg ggcaggagga tggagtcgcg ataccactgc caggcgtcag 2100

 gaaaggtgac atgagttctc ggcacttcaa acctgagatc agggtgacct 2150

 cactccgctt ctctcccact gggcgctgct gggcgggcac caccacggag 2200

 ggactcctca tctactccct ggacacccgc gtgctctttg acccgtttga 2250

 gctggacacc agcgtcaccc ccgggagggt gcgcgaggca ctgcgccagc 2300

 aggacttcac cagggccatc ctcatggccc tccggctcaa cgagagcaaa 2350

 ctggtgcagg aggccctgga ggcggtgccc aggggcgaga ttgaagtggt 2400

 cacctcctcc cttcctgaac tgtatgtgga gaaagtgctg gagtttttag 2450

 cttcctcctt tgaagtgtct cgccacctgg aattctacct cctctggact 2500

 cacaaactgc tcatgttgca cggacagaag ctgaagtcca gagccgggac 2550

 gctgctgcct gtcattcagt tcctccagaa gagcatccag cggcacctgg 2600

 acgacctgtc gaaactctgt agctggaacc actataacat gcagtacgca 2650

 ctagcagttt ccaagcagcg gggcacaaaa cgctccctag acccgctggg 2700

 aagtgaggag gaggcagaag catctgaaga tgacagcctg catctgcttg 2750

 gaggaggagg cagagactca gaagaagaga tgctggccta gagccagccg 2800

 gttgcagcgt tggattgtgc cggctaagac ctgccaggga gatgggaccc 2850

 ttgtgccacc tgggccagca aagaggaggg gtccagagaa cagctgaaat 2900

 actgtcacta gtggtagtga cttgcttttc ctgtgcacac atgtagccca 2950

 tcaggacagc gagccgacgg gtcacgccag gggccggcac gcactggcac 3000

 ctggccccag gagcgggccc gtgtgaacgg tgatgaatgt tgaaaatgcg 3050

 tctcagagag gtattcacat gaactttgta tgagacttat ttatattttt 3100

 aacataaagg tttgataaag aacttaggga ttaaaaaaaa gatggagttt 3150

 tctaacgtga ggatgaagtc tacacttcag attaaaaagg gttatgttgt 3200

 a 3201

<210> 1991
<211> 919
<212> PRT
<213> Homo sapien

<400> 1991
 Met Lys Phe Ala Tyr Arg Phe Ser Asn Leu Leu Gly Thr Val Tyr
   1               5                  10                  15

 Arg Arg Gly Asn Leu Asn Phe Thr Cys Asn Gly Asn Ser Val Ile
                  20                  25                  30

 Ser Pro Val Gly Asn Arg Val Thr Val Phe Asp Leu Lys Asn Asn
                  35                  40                  45

 Lys Ser Asp Thr Leu Pro Leu Ala Thr Arg Tyr Asn Val Lys Cys
                  50                  55                  60

 Val Gly Leu Ser Pro Asp Gly Arg Leu Ala Ile Ile Val Asp Glu
                  65                  70                  75

 Gly Gly Asp Ala Leu Leu Val Ser Leu Val Cys Arg Ser Val Leu
                  80                  85                  90

 His His Phe His Phe Lys Gly Ser Val His Ser Val Ser Phe Ser
                  95                 100                 105

 Pro Asp Gly Arg Lys Phe Val Val Thr Lys Gly Asn Ile Ala Gln
                 110                 115                 120

 Met Tyr His Ala Pro Gly Lys Lys Arg Glu Phe Asn Ala Phe Val
                 125                 130                 135

 Leu Asp Lys Thr Tyr Phe Gly Pro Tyr Asp Glu Thr Thr Cys Ile
                 140                 145                 150

 Asp Trp Thr Asp Asp Ser Arg Cys Phe Val Val Gly Ser Lys Asp
                 155                 160                 165

 Met Ser Thr Trp Val Phe Gly Ala Glu Arg Trp Asp Asn Leu Ile
                 170                 175                 180

 Tyr Tyr Ala Leu Gly Gly His Lys Asp Ala Ile Val Ala Cys Phe
                 185                 190                 195

 Phe Glu Ser Asn Ser Leu Asp Leu Tyr Ser Leu Ser Gln Asp Gly
                 200                 205                 210

 Val Leu Cys Met Trp Gln Cys Asp Thr Pro Pro Glu Gly Leu Arg
                 215                 220                 225

 Leu Lys Pro Pro Ala Gly Trp Lys Ala Asp Leu Leu Gln Arg Glu
                 230                 235                 240

 Glu Glu Glu Glu Glu Glu Glu Asp Gln Glu Gly Asp Arg Glu Thr
                 245                 250                 255

 Thr Ile Arg Gly Lys Ala Thr Pro Ala Glu Glu Glu Lys Thr Gly
                 260                 265                 270

 Lys Val Lys Tyr Ser Arg Leu Ala Lys Tyr Phe Phe Asn Lys Glu
                 275                 280                 285

 Gly Asp Phe Asn Asn Leu Thr Ala Ala Ala Phe His Lys Lys Ser
                 290                 295                 300

 His Leu Leu Val Thr Gly Phe Ala Ser Gly Ile Phe His Leu His
                 305                 310                 315

 Glu Leu Pro Glu Phe Asn Leu Ile His Ser Leu Ser Ile Ser Asp
                 320                 325                 330

 Gln Ser Ile Ala Ser Val Ala Ile Asn Ser Ser Gly Asp Trp Ile
                 335                 340                 345

 Ala Phe Gly Cys Ser Gly Leu Gly Gln Leu Leu Val Trp Glu Trp
                 350                 355                 360

 Gln Ser Glu Ser Tyr Val Leu Lys Gln Gln Gly His Phe Asn Ser
                 365                 370                 375

 Met Val Ala Leu Ala Tyr Ser Pro Asp Gly Gln Tyr Ile Val Thr
                 380                 385                 390

 Gly Gly Asp Asp Gly Lys Val Lys Val Trp Asn Thr Leu Ser Gly
                 395                 400                 405

 Phe Cys Phe Val Thr Phe Thr Glu His Ser Ser Gly Val Thr Gly
                 410                 415                 420

 Val Thr Phe Thr Ala Thr Gly Tyr Val Val Val Thr Ser Ser Met
                 425                 430                 435

 Asp Gly Thr Val Arg Ala Phe Asp Leu His Arg Tyr Arg Asn Phe
                 440                 445                 450

 Arg Thr Phe Thr Ser Pro Arg Pro Thr Gln Phe Ser Cys Val Ala
                 455                 460                 465

 Val Asp Ala Ser Gly Glu Ile Val Ser Ala Gly Ala Gln Asp Ser
                 470                 475                 480

 Phe Glu Ile Phe Val Trp Ser Met Gln Thr Gly Arg Leu Leu Asp
                 485                 490                 495

 Val Leu Ser Gly His Glu Gly Pro Ile Ser Gly Leu Cys Phe Asn
                 500                 505                 510

 Pro Met Lys Ser Val Leu Ala Ser Ala Ser Trp Asp Lys Thr Val
                 515                 520                 525

 Arg Leu Trp Asp Met Phe Asp Ser Trp Arg Thr Lys Glu Thr Leu
                 530                 535                 540

 Ala Leu Thr Ser Asp Ala Leu Ala Val Thr Phe Arg Pro Asp Gly
                 545                 550                 555

 Ala Glu Leu Ala Val Ala Thr Leu Asn Ser Gln Ile Thr Phe Trp
                 560                 565                 570

 Asp Pro Glu Asn Ala Val Gln Thr Gly Ser Ile Glu Gly Arg His
                 575                 580                 585

 Asp Leu Lys Thr Gly Arg Lys Glu Leu Asp Lys Ile Thr Ala Lys
                 590                 595                 600

 His Ala Ala Lys Gly Lys Ala Phe Thr Ala Leu Cys Tyr Ser Ala
                 605                 610                 615

 Asp Gly His Ser Ile Leu Ala Gly Gly Met Ser Lys Phe Val Cys
                 620                 625                 630

 Ile Tyr His Val Arg Glu Gln Ile Leu Met Lys Arg Phe Glu Ile
                 635                 640                 645

 Ser Cys Asn Leu Ser Leu Asp Ala Met Glu Glu Phe Leu Asn Arg
                 650                 655                 660

 Arg Lys Met Thr Glu Phe Gly Asn Leu Ala Leu Ile Asp Gln Asp
                 665                 670                 675

 Ala Gly Gln Glu Asp Gly Val Ala Ile Pro Leu Pro Gly Val Arg
                 680                 685                 690

 Lys Gly Asp Met Ser Ser Arg His Phe Lys Pro Glu Ile Arg Val
                 695                 700                 705

 Thr Ser Leu Arg Phe Ser Pro Thr Gly Arg Cys Trp Ala Gly Thr
                 710                 715                 720

 Thr Thr Glu Gly Leu Leu Ile Tyr Ser Leu Asp Thr Arg Val Leu
                 725                 730                 735

 Phe Asp Pro Phe Glu Leu Asp Thr Ser Val Thr Pro Gly Arg Val
                 740                 745                 750

 Arg Glu Ala Leu Arg Gln Gln Asp Phe Thr Arg Ala Ile Leu Met
                 755                 760                 765

 Ala Leu Arg Leu Asn Glu Ser Lys Leu Val Gln Glu Ala Leu Glu
                 770                 775                 780

 Ala Val Pro Arg Gly Glu Ile Glu Val Val Thr Ser Ser Leu Pro
                 785                 790                 795

 Glu Leu Tyr Val Glu Lys Val Leu Glu Phe Leu Ala Ser Ser Phe
                 800                 805                 810

 Glu Val Ser Arg His Leu Glu Phe Tyr Leu Leu Trp Thr His Lys
                 815                 820                 825

 Leu Leu Met Leu His Gly Gln Lys Leu Lys Ser Arg Ala Gly Thr
                 830                 835                 840

 Leu Leu Pro Val Ile Gln Phe Leu Gln Lys Ser Ile Gln Arg His
                 845                 850                 855

 Leu Asp Asp Leu Ser Lys Leu Cys Ser Trp Asn His Tyr Asn Met
                 860                 865                 870

 Gln Tyr Ala Leu Ala Val Ser Lys Gln Arg Gly Thr Lys Arg Ser
                 875                 880                 885

 Leu Asp Pro Leu Gly Ser Glu Glu Glu Ala Glu Ala Ser Glu Asp
                 890                 895                 900

 Asp Ser Leu His Leu Leu Gly Gly Gly Gly Arg Asp Ser Glu Glu
                 905                 910                 915

 Glu Met Leu Ala


<210> 1992
<211> 2240
<212> DNA
<213> Homo sapien

<400> 1992
 ccccgcgggc tgcagcgagc caggcatgct cactggcgca ggcccggccc 50

 gcagcccgag caggaagcgc cggcgtaggc ggccccctgc gctgccagct 100

 ggagccgggc ggagccagcg ccccggcgca gggtggctct gccagtcccc 150

 gcgcgcctgg gcggccgcac acgtgtccag gcgtcacgtc cgcgcgcgcc 200

 cccggggctt gcgtcagcgg ctgttccaga agcgggtggg ccagggctct 250

 gcgcaccgct ggggttcggg gcccgggacg ccgccgggag gagggcaccg 300

 cgcggggtcc gacgcggagg cgtgctcgga acgccggggg ctgcggagtg 350

 catcagcgcg gtccagccct ccgcctgccg ggcgccgagc gtctccgccg 400

 cccggacctg ggctgggcgc cgtggcgttg cctcggagct cgctgcccgc 450

 ggggcgcgca ccgccttgac ccgggcggcc ccgcggcagg caggcgcccg 500

 cagttccatg gttggttcgg agcgcgatga gccgcccgtc ctccaccggc 550

 cccagcgcta ataaaccctg cagcaagcag ccgccgccgc agccccagca 600

 cactccgtcc ccggctgcgc ccccggccgc cgccaccatc tcggctgcgg 650

 gccccggctc gtccgcggtg cccgccgcgg cggcggtgat ctcgggcccc 700

 ggcggcggcg gcggggccgg cccggtgtcc ccgcagcacc acgagctgac 750

 ctcgctcttc gagtgtccgg tctgctttga ctatgtcctg cctcctattc 800

 tgcagtgcca ggccgggcac ctggtgtgta accaatgccg ccagaagttg 850

 agctgctgcc cgacgtgcag gggcgccctg acgcccagca tcaggaacct 900

 ggctatggag aaggtggcct cggcagtcct gtttccctgt aagtatgcca 950

 ccacgggctg ttccctgacc ctgcaccata cggagaaacc agaacatgaa 1000

 gacatatgtg aataccgccc ctactcctgc ccatgtcctg gtgcttcctg 1050

 caagtggcag gggtccctgg aagctgtgat gtcccatctc atgcacgccc 1100

 acaagagcat taccaccctt caggaagaag acatcgtctt tctagctaca 1150

 gacattaact tgccaggggc tgtcgactgg gtgatgatgc agtcatgttt 1200

 tggccatcac ttcatgctgg tgctggagaa acaagagaag tacgaaggcc 1250

 accagcagtt ttttgccatc gtcctgctca ttggcacccg caagcaagcc 1300

 gagaactttg cctacagact ggagttgaat gggaaccggc ggagattgac 1350

 ctgggaggcc acgccccgct cgattcatga cggtgtggct gcggccatca 1400

 tgaacagcga ctgccttgtt ttcgacacag ccatagcaca tctttttgca 1450

 gataatggga accttggaat caatgttact atttctacat gttgtccatg 1500

 atgtgacttc cgtaaacctt caaaattatt tgggcatact gctctatgtt 1550

 taataaaggt ttttatagat gttttattcc atatgtcttc acaagtcagg 1600

 acccacaatt acccgtgttt tgtttgaaca gcagtgtccc atctggcttc 1650

 gacccaacaa agttcattaa cctgggatga atggggttgg cctgttggtg 1700

 atttggatgc tgttctgtga tctaaaacaa ctcttattga attgtattta 1750

 ctccctaaac aacacttgac aggctgttgc acagggcttc tatagatcag 1800

 tgtgttagga atgggaggcc ccttcctgcc tgccttccca tattggtccc 1850

 ttgacattga caaaagcaca gtgactgtca gcagattcct ttacttttgt 1900

 ttgtgggagg taggaattgt tttaatgcat tttaaacagt gtttctgaaa 1950

 ttggatggct ggctaataga cactgaatca cccggagtgc ttatcttaaa 2000

 attgcagatt tagggagcct gccaatttaa cagtctcatc agtgatcttt 2050

 caacagtaat gtttgagaat tactgggtta aattgtggaa agggtccaga 2100

 ttttaaaggt gctttaaggt tgccctctgc cgatactgtt tgtctttcta 2150

 ctgtttcatc ccctaacttc ccccaaccct caaattaaaa ctagaactat 2200

 agatccacat gaacgcacgc ctgagatttg gccactcacc 2240

<210> 1993
<211> 324
<212> PRT
<213> Homo sapien

<400> 1993
 Met Ser Arg Pro Ser Ser Thr Gly Pro Ser Ala Asn Lys Pro Cys
   1               5                  10                  15

 Ser Lys Gln Pro Pro Pro Gln Pro Gln His Thr Pro Ser Pro Ala
                  20                  25                  30

 Ala Pro Pro Ala Ala Ala Thr Ile Ser Ala Ala Gly Pro Gly Ser
                  35                  40                  45

 Ser Ala Val Pro Ala Ala Ala Ala Val Ile Ser Gly Pro Gly Gly
                  50                  55                  60

 Gly Gly Gly Ala Gly Pro Val Ser Pro Gln His His Glu Leu Thr
                  65                  70                  75

 Ser Leu Phe Glu Cys Pro Val Cys Phe Asp Tyr Val Leu Pro Pro
                  80                  85                  90

 Ile Leu Gln Cys Gln Ala Gly His Leu Val Cys Asn Gln Cys Arg
                  95                 100                 105

 Gln Lys Leu Ser Cys Cys Pro Thr Cys Arg Gly Ala Leu Thr Pro
                 110                 115                 120

 Ser Ile Arg Asn Leu Ala Met Glu Lys Val Ala Ser Ala Val Leu
                 125                 130                 135

 Phe Pro Cys Lys Tyr Ala Thr Thr Gly Cys Ser Leu Thr Leu His
                 140                 145                 150

 His Thr Glu Lys Pro Glu His Glu Asp Ile Cys Glu Tyr Arg Pro
                 155                 160                 165

 Tyr Ser Cys Pro Cys Pro Gly Ala Ser Cys Lys Trp Gln Gly Ser
                 170                 175                 180

 Leu Glu Ala Val Met Ser His Leu Met His Ala His Lys Ser Ile
                 185                 190                 195

 Thr Thr Leu Gln Glu Glu Asp Ile Val Phe Leu Ala Thr Asp Ile
                 200                 205                 210

 Asn Leu Pro Gly Ala Val Asp Trp Val Met Met Gln Ser Cys Phe
                 215                 220                 225

 Gly His His Phe Met Leu Val Leu Glu Lys Gln Glu Lys Tyr Glu
                 230                 235                 240

 Gly His Gln Gln Phe Phe Ala Ile Val Leu Leu Ile Gly Thr Arg
                 245                 250                 255

 Lys Gln Ala Glu Asn Phe Ala Tyr Arg Leu Glu Leu Asn Gly Asn
                 260                 265                 270

 Arg Arg Arg Leu Thr Trp Glu Ala Thr Pro Arg Ser Ile His Asp
                 275                 280                 285

 Gly Val Ala Ala Ala Ile Met Asn Ser Asp Cys Leu Val Phe Asp
                 290                 295                 300

 Thr Ala Ile Ala His Leu Phe Ala Asp Asn Gly Asn Leu Gly Ile
                 305                 310                 315

 Asn Val Thr Ile Ser Thr Cys Cys Pro
                 320

<210> 1994
<211> 3517
<212> DNA
<213> Homo sapien

<400> 1994
 tgctgctgtc ctggagggaa atggagcagg ctgtggagct ctgtgggcgg 50

 gtaggagact catttgggtt tcggaactta ccaagggggt gagattttgt 100

 gctcccactt ttcactttct catcaaacac tgggtcgatc tctgtcaaaa 150

 atcaggtgtt cctcaccatg ctttgagctt aactggacca gctgaaaaga 200

 ggccaagaga gtagccagtg aagggagccc ctctgtggcc agatgcaaga 250

 gctgcatgaa tggacagaga tggtccaggt ttaaataaga agcaagggtt 300

 aggttccctt ggggaaaagc caagaccatt tcctgttagg aagggcattg 350

 gatggatgat caacactccc tcttgtcgaa ggtttttgac taattttgtt 400

 gggatgctaa atccatagga aataaaaggt ctaggcagaa agtctcaggg 450

 cagcgtaaat cagatgtcac caaaaaaagt taattatgaa ggcaaaggaa 500

 atacatgtga cttaatgaac ctcacacaaa ctgaaggttg aagtcaggct 550

 ccggggcttt ttcctggact tatcctctgt tttcccctgt gtacttgggc 600

 aaggatcttc acctgtgtct tagtatcgat ttttatgaat cagtactgat 650

 ggagtatatg tgtgtttaat ggtgaatatt aaccatagaa gggctgagtg 700

 ctcctcccca tcttgggact cataatctgt gaaataaaac agtctgggcc 750

 tccctgcccg ggtagcatca ggatagacag atgaagagaa gagaaagtaa 800

 tgtgtcttgg gcatcttctg tatgccaggc accatgccag aggctttaag 850

 tacttcatct tacttgactc ctcagatggc cctgttagaa gcctatttta 900

 tgcaaaagga aactgtagct gggggtaagt aacttgccaa ggggtcacac 950

 agctagaaag cggtggaccc tagatgcagg cgcagggcat tcagacccca 1000

 cagtccacat tcctttgagc cagtccattg agggtcctca gggaatgtgg 1050

 cgggtcccct ggtctcgctc ccccgcagat cttgcatctc agcatgcgcc 1100

 taccacatca gttgacatta gcacagcttt tccattagga gaacgaagtg 1150

 aaactcctgg tagaacggat gatggctctg cagaccgaca ttgtggactt 1200

 acagaggagc cccatgggcc ggaagcaggg gggaacgctg gacgacctag 1250

 aggagcaagc aagggagctg tacaggagac taagggaaaa acctcgagac 1300

 cagcgaactg agggtgacag tcaggaaatg gtacggctgc tgcttcaggc 1350

 aattcagagc ttcgagaaga aagtgcgagt gatctatacg cagctcagta 1400

 aaactgtggt ttgcaagcag aaggcgctgg aactgttgcc caaggtggaa 1450

 gaggtggtga gcttaatgaa tgaggatgag aagactgttg tccggctgca 1500

 ggagaagcgg cagaaggagc tctggaatct cctgaagatt gcttgtagca 1550

 aggtccgtgg tcctgtcagt ggaagcccgg atagcatgaa tgcctctcga 1600

 cttagccagc ctgggcagct gatgtctcag ccctccacgg cctccaacag 1650

 cttacctgag ccagccaaga agagtgaaga actggtggct gaagcacata 1700

 acctctgcac cctgctagaa aatgccatac aggacactgt gagggaacaa 1750

 gaccagagtt tcacggccct agactggagc tggttacaga cggaagaaga 1800

 agagcacagc tgcctggagc aggcctcatg atgtgggggg actcgacccc 1850

 ctgacatggg gcagcccata gcaggccttg tgcggtgggg ggactcgacc 1900

 ccctgacatg gggctgcctg gagcaggccg cgtgacgtgg ggctgcctgg 1950

 ccgcggctct cacatggtgg ttcctgctgc actgatggcc caggggtctc 2000

 tggtatccag atggagctct cgcttcctca gcagctgtga ctttcaccca 2050

 ggacccagga cgcagccctc cgtgggcact gccggcgcct tgtctgcaca 2100

 ctggaggtcc tccattacag aggcccagcg cacatcgctg gccccacaaa 2150

 cgttcagggg tacagccatg gcagctcctt cctctgccgt gagaaaagtg 2200

 cttggagtac ggtttgccac acacgtgact ggacagtgtc caattcaaat 2250

 ctttcagggc agagtccgag cagcgcttgg tgacagcctg tcctctcctg 2300

 ctctccaaag gccctgctcc ctgtcctctc tcactttaca gcttgtgttt 2350

 cttctggatt cagcttctcc taaacagaca gtttaattat agttgcggcc 2400

 tggccccatc ctcacttcct ctttttattt cactgctgct aaaattgtgt 2450

 ttttacctac tactttggtg gttgtcctct tttcggcaaa gttggagcga 2500

 gtgccaagct ctccatctgt ggtcctttct gccaagagcg actcatagta 2550

 accaggatgg gagagcagct gccttattct gaatcccaaa aattacttgg 2600

 gggtgattgt cacagaggag ggacagaaag ggtatctgct gaccaccagc 2650

 ctgcctaccc atgcccatgt ctccattcct gctcaagcgt gtgtgctggg 2700

 ccggggagtc cctgtctctc acagcatcta gcagtattat taaatggatt 2750

 cattttaaaa atagctccta tattttgtaa catgtctcaa acactcatac 2800

 tgggttccac aatccactgt tagaatacct atggttaggg cttctgaact 2850

 aaaataatgg aaaattttaa caatttgtat agtgcctgga tcattactag 2900

 tgccataacc ctgcttcttc aacatttcac agaacttctc ttttatataa 2950

 aggcaagagc acaaaatgag ttcagatgat cacaaacagg tgagttttgt 3000

 tggagaagaa agttggagta ggagactttc acaagtggtt tccatggaga 3050

 tagaatgaag cattctgtgg tcaagtaagt ttagggagct attcatgttt 3100

 cacttgcttt gtggagattc acactatgca ctgggaaagt atctgaaaag 3150

 tcttataata aagaaacagg cttaactttg tgtaagaaca ctgtttatca 3200

 atgtcatttg gctatagaaa cattttctcc tgctgattgt gtgtgtgaaa 3250

 catgtattaa cattccaatg aactagcatt taataaagca caattttgga 3300

 aaccctggta aatgacagtg ggaaataaca cccgaaaggc aaggacgggc 3350

 agattgggga gggaaaggat gttgggctaa gggctgtgag cttatgttac 3400

 aggcaactga gccactgaag aattttgacg aagaaaatgc caaccaaagc 3450

 agtcatttta aaagtttatg gctgttcagt tacaggacaa gttgtgaaaa 3500

 gaaagaaaaa aaaatgg 3517

<210> 1995
<211> 220
<212> PRT
<213> Homo sapien

<400> 1995
 Met Met Ala Leu Gln Thr Asp Ile Val Asp Leu Gln Arg Ser Pro
   1               5                  10                  15

 Met Gly Arg Lys Gln Gly Gly Thr Leu Asp Asp Leu Glu Glu Gln
                  20                  25                  30

 Ala Arg Glu Leu Tyr Arg Arg Leu Arg Glu Lys Pro Arg Asp Gln
                  35                  40                  45

 Arg Thr Glu Gly Asp Ser Gln Glu Met Val Arg Leu Leu Leu Gln
                  50                  55                  60

 Ala Ile Gln Ser Phe Glu Lys Lys Val Arg Val Ile Tyr Thr Gln
                  65                  70                  75

 Leu Ser Lys Thr Val Val Cys Lys Gln Lys Ala Leu Glu Leu Leu
                  80                  85                  90

 Pro Lys Val Glu Glu Val Val Ser Leu Met Asn Glu Asp Glu Lys
                  95                 100                 105

 Thr Val Val Arg Leu Gln Glu Lys Arg Gln Lys Glu Leu Trp Asn
                 110                 115                 120

 Leu Leu Lys Ile Ala Cys Ser Lys Val Arg Gly Pro Val Ser Gly
                 125                 130                 135

 Ser Pro Asp Ser Met Asn Ala Ser Arg Leu Ser Gln Pro Gly Gln
                 140                 145                 150

 Leu Met Ser Gln Pro Ser Thr Ala Ser Asn Ser Leu Pro Glu Pro
                 155                 160                 165

 Ala Lys Lys Ser Glu Glu Leu Val Ala Glu Ala His Asn Leu Cys
                 170                 175                 180

 Thr Leu Leu Glu Asn Ala Ile Gln Asp Thr Val Arg Glu Gln Asp
                 185                 190                 195

 Gln Ser Phe Thr Ala Leu Asp Trp Ser Trp Leu Gln Thr Glu Glu
                 200                 205                 210

 Glu Glu His Ser Cys Leu Glu Gln Ala Ser
                 215                 220

<210> 1996
<211> 2145
<212> DNA
<213> Homo sapien

<400> 1996
 atcttttttc atcttctagc tgtagctcgg gctgcttgtc ggcttggctc 50

 cccctccccc ctttgctctc tgcctcgtct ttccccagga cttcgctatt 100

 ttgctttttt aaaaaaaggc aagaaagaac taaactcccc cctccctctc 150

 ctccagtcgg gctgcacctc tgccttgcac tttgcacaga ggtagagagc 200

 gcgcgaggga gagagaggaa agaaaaaaaa taataaagag agccaagcag 250

 aagaggaggc gagaagcatg aagtgttaac tcccccgtgc caaggcccgc 300

 gccgcccgga cagacgcccg ccgcgccttc cagccccgag cggacgccgc 350

 gcgccgccct gcctgcagcc cgggccggcg acggcgagcc cttccttatg 400

 caaagcgcgc cagcagcgcg aaggcgggac gccgcgcacc gggccgggct 450

 cctccagctt cgccgccgca gccaccaccg ccgccaccgc agctcgcgga 500

 ggatcttccc gagcctgaag ccgccggctc ggcgcgcaag gaggcgagcg 550

 caaggagggg ccggggcgag cgagggagca cattggcgtg agcagggggg 600

 agggagggcg ggcgcggggg gcgcgggcag ggcggggggg tgtgtgtgtg 650

 agcgcgcttg gaggtttcgg gccagccacc gccgcgcaag ctagaagcgc 700

 cccagcccgg caagctggct cacccgctgg ccacccagca cagcccgctg 750

 gcccctctcc tgcagcccat ctggcggagc ggcggcggcg gcggcggcgg 800

 caggagaatg gcatcagaac tggcaatgag caactccgac ctgcccacca 850

 gtcccctggc catggaatat gttaatgact tcgatctgat gaagtttgaa 900

 gtgaaaaagg aaccggtgga gaccgaccgc atcatcagcc agtgcggccg 950

 tctcatcgcc gggggctcgc tgtcctccac ccccatgagc acgccgtgca 1000

 gctcggtgcc cccttccccc agcttctcgg cgcccagccc gggctcgggc 1050

 agcgagcaga aggcgcacct ggaagactac tactggatga ccggctaccc 1100

 gcagcagctg aaccccgagg cgctgggctt cagccccgag gacgcggtcg 1150

 aggcgctcat cagcaacagc caccagctcc agggcggctt cgatggctac 1200

 gcgcgcgggg cgcagcagct ggccgcggcg gccggggccg gtgccggcgc 1250

 ctccttgggc ggcagcggcg aggagatggg ccccgcggcc gccgtggtgt 1300

 ccgccgtgat cgccgcggcc gccgcgcaga gcggcgcggg cccgcactac 1350

 caccaccacc accaccacgc cgccggccac caccaccacc cgacggccgg 1400

 cgcgcccggc gccgcgggca gcgcggccgc ctcggccggt ggcgctgggg 1450

 gcgcgggcgg cggtggcccg gccagcgctg ggggcggcgg cggcggcggc 1500

 ggcggcggag gcggcggggg cgcggcgggg gcggggggcg ccctgcaccc 1550

 gcaccacgcc gccggcggcc tgcacttcga cgaccgcttc tccgacgagc 1600

 agctggtgac catgtctgtg cgcgagctga accggcagct gcgcggggtc 1650

 agcaaggagg aggtgatccg gctgaagcag aagaggcgga ccctgaaaaa 1700

 ccgcggctat gcccagtcct gccgcttcaa gagggtgcag cagagacacg 1750

 tcctggagtc ggagaagaac cagctgctgc agcaagtcga ccacctcaag 1800

 caggagatct ccaggctggt gcgcgagagg gacgcgtaca aggagaaata 1850

 cgagaagttg gtgagcagcg gcttccgaga aaacggctcg agcagcgaca 1900

 acccgtcctc tcccgagttt ttcataactg agcccactcg caagttggag 1950

 ccatcagtgg gatacgccac attttggaag ccccagcatc gtgtacttac 2000

 cagtgtgttc acaaaatgaa atttgtgtga gagctgtaca ttaaaaaaaa 2050

 catcattatt attattattt gcagtcatgg agaaccacct acccctgact 2100

 tctgtttagt ctccttttta aataatactg tgttagaaaa aaaaa 2145

<210> 1997
<211> 403
<212> PRT
<213> Homo sapien

<400> 1997
 Met Ala Ser Glu Leu Ala Met Ser Asn Ser Asp Leu Pro Thr Ser
   1               5                  10                  15

 Pro Leu Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Met Lys Phe
                  20                  25                  30

 Glu Val Lys Lys Glu Pro Val Glu Thr Asp Arg Ile Ile Ser Gln
                  35                  40                  45

 Cys Gly Arg Leu Ile Ala Gly Gly Ser Leu Ser Ser Thr Pro Met
                  50                  55                  60

 Ser Thr Pro Cys Ser Ser Val Pro Pro Ser Pro Ser Phe Ser Ala
                  65                  70                  75

 Pro Ser Pro Gly Ser Gly Ser Glu Gln Lys Ala His Leu Glu Asp
                  80                  85                  90

 Tyr Tyr Trp Met Thr Gly Tyr Pro Gln Gln Leu Asn Pro Glu Ala
                  95                 100                 105

 Leu Gly Phe Ser Pro Glu Asp Ala Val Glu Ala Leu Ile Ser Asn
                 110                 115                 120

 Ser His Gln Leu Gln Gly Gly Phe Asp Gly Tyr Ala Arg Gly Ala
                 125                 130                 135

 Gln Gln Leu Ala Ala Ala Ala Gly Ala Gly Ala Gly Ala Ser Leu
                 140                 145                 150

 Gly Gly Ser Gly Glu Glu Met Gly Pro Ala Ala Ala Val Val Ser
                 155                 160                 165

 Ala Val Ile Ala Ala Ala Ala Ala Gln Ser Gly Ala Gly Pro His
                 170                 175                 180

 Tyr His His His His His His Ala Ala Gly His His His His Pro
                 185                 190                 195

 Thr Ala Gly Ala Pro Gly Ala Ala Gly Ser Ala Ala Ala Ser Ala
                 200                 205                 210

 Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Pro Ala Ser Ala Gly
                 215                 220                 225

 Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala
                 230                 235                 240

 Gly Ala Gly Gly Ala Leu His Pro His His Ala Ala Gly Gly Leu
                 245                 250                 255

 His Phe Asp Asp Arg Phe Ser Asp Glu Gln Leu Val Thr Met Ser
                 260                 265                 270

 Val Arg Glu Leu Asn Arg Gln Leu Arg Gly Val Ser Lys Glu Glu
                 275                 280                 285

 Val Ile Arg Leu Lys Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly
                 290                 295                 300

 Tyr Ala Gln Ser Cys Arg Phe Lys Arg Val Gln Gln Arg His Val
                 305                 310                 315

 Leu Glu Ser Glu Lys Asn Gln Leu Leu Gln Gln Val Asp His Leu
                 320                 325                 330

 Lys Gln Glu Ile Ser Arg Leu Val Arg Glu Arg Asp Ala Tyr Lys
                 335                 340                 345

 Glu Lys Tyr Glu Lys Leu Val Ser Ser Gly Phe Arg Glu Asn Gly
                 350                 355                 360

 Ser Ser Ser Asp Asn Pro Ser Ser Pro Glu Phe Phe Ile Thr Glu
                 365                 370                 375

 Pro Thr Arg Lys Leu Glu Pro Ser Val Gly Tyr Ala Thr Phe Trp
                 380                 385                 390

 Lys Pro Gln His Arg Val Leu Thr Ser Val Phe Thr Lys
                 395                 400

<210> 1998
<211> 4246
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3300
<223> Unknown base

<400> 1998
 atcttttttc atcttctagc tgtagctcgg gctgcttgtc ggcttggctc 50

 cccctccccc ctttgctctc tgcctcgtct ttccccagga cttcgctatt 100

 ttgctttttt aaaaaaaggc aagaaagaac taaactcccc cctccctctc 150

 ctccagtcgg gctgcacctc tgccttgcac tttgcacaga ggtagagagc 200

 gcgcgaggga gagagaggaa agaaaaaaaa taataaagag agccaagcag 250

 aagaggaggc gagaagcatg aagtgttaac tcccccgtgc caaggcccgc 300

 gccgcccgga cagacgcccg ccgcgccttc cagccccgag cggacgccgc 350

 gcgccgccct gcctgcagcc cgggccggcg acggcgagcc cttccttatg 400

 caaagcgcgc cagcagcgcg aaggcgggac gccgcgcacc gggccgggct 450

 cctccagctt cgccgccgca gccaccaccg ccgccaccgc agctcgcgga 500

 ggatcttccc gagcctgaag ccgccggctc ggcgcgcaag gaggcgagcg 550

 caaggagggg ccggggcgag cgagggagca cattggcgtg agcagggggg 600

 agggagggcg ggcgcggggg gcgcgggcag ggcggggggg tgtgtgtgtg 650

 agcgcgcttg gaggtttcgg gccagccacc gccgcgcaag ctagaagcgc 700

 cccagcccgg caagctggct cacccgctgg ccacccagca cagcccgctg 750

 gcccctctcc tgcagcccat ctggcggagc ggcggcggcg gcggcggcgg 800

 caggagaatg gcatcagaac tggcaatgag caactccgac ctgcccacca 850

 gtcccctggc catggaatat gttaatgact tcgatctgat gaagtttgaa 900

 gtgaaaaagg aaccggtgga gaccgaccgc atcatcagcc agtgcggccg 950

 tctcatcgcc gggggctcgc tgtcctccac ccccatgagc acgccgtgca 1000

 gctcggtgcc cccttccccc agcttctcgg cgcccagccc gggctcgggc 1050

 agcgagcaga aggcgcacct ggaagactac tactggatga ccggctaccc 1100

 gcagcagctg aaccccgagg cgctgggctt cagccccgag gacgcggtcg 1150

 aggcgctcat cagcaacagc caccagctcc agggcggctt cgatggctac 1200

 gcgcgcgggg cgcagcagct ggccgcggcg gccggggccg gtgccggcgc 1250

 ctccttgggc ggcagcggcg aggagatggg ccccgcggcc gccgtggtgt 1300

 ccgccgtgat cgccgcggcc gccgcgcaga gcggcgcggg cccgcactac 1350

 caccaccacc accaccacgc cgccggccac caccaccacc cgacggccgg 1400

 cgcgcccggc gccgcgggca gcgcggccgc ctcggccggt ggcgctgggg 1450

 gcgcgggcgg cggtggcccg gccagcgctg ggggcggcgg cggcggcggc 1500

 ggcggcggag gcggcggggg cgcggcgggg gcggggggcg ccctgcaccc 1550

 gcaccacgcc gccggcggcc tgcacttcga cgaccgcttc tccgacgagc 1600

 agctggtgac catgtctgtg cgcgagctga accggcagct gcgcggggtc 1650

 agcaaggagg aggtgatccg gctgaagcag aagaggcgga ccctgaaaaa 1700

 ccgcggctat gcccagtcct gccgcttcaa gagggtgcag cagagacacg 1750

 tcctggagtc ggagaagaac cagctgctgc agcaagtcga ccacctcaag 1800

 caggagatct ccaggctggt gcgcgagagg gacgcgtaca aggagaaata 1850

 cgagaagttg gtgagcagcg gcttccgaga aaacggctcg agcagcgaca 1900

 acccgtcctc tcccgagttt ttcatgtgag tctgacacgc gattccagct 1950

 agccaccctg ataagtgctc cgcgggggtc cggctcgggt gtgggcttgc 2000

 tagttctaga gccatgctcg ccaccacctc accaccccca cccccaccga 2050

 gtttggcccc cttggccccc tacacacaca caaacccgca cgcacacacc 2100

 acacacacac acacacacac acacacacac cccacaccct gctcgagttt 2150

 gtggtggtgg tggctgtttt aaactgggga gggaatgggt gtctggctca 2200

 tggattgcca atctgaaatt ctccataact tgctagcttg tttttttttt 2250

 ttttttttac acccccccgc cccacccccc ggacttgcac aatgttcaat 2300

 gatctcagca gagttcttca tgtgaaacgt tgatcacctt tgaagcctgc 2350

 atcattcaca tattttttct tcttcttccc cttcagttca tgaactggtg 2400

 ttcattttct gtgtgtgtgt gtgttttatt ttgtttggat tttttttttt 2450

 aattttactt ttagagcttg ctgtgcttgc ccacctcttt tccaacctcc 2500

 accctcactc cttctcaacc catctcttcc gagatgaaag aaaaaaaaaa 2550

 gcaaagtttt tttttcttct cctgagttct tcagtgagat tgagcttgca 2600

 aaggaaaaaa aaatgtgaaa tgttatagac ttgcagcgtg ccgagttcca 2650

 tcgggttttt tttttagcat tgttatgcta aaatagagaa aaaaatcctc 2700

 atgaaccttc cacaatcaag cctgcatcaa ccttctgggt gtgacttgtg 2750

 agttttggcc ttgtgatgcc aaatctgaga gtttagtctg ccattaaaaa 2800

 aactcattct catctcatgc attattatgc ttgctacttt gtcttagcaa 2850

 caatgaacta taactgtttc aaagacttta tggaaaagag acattatatt 2900

 aataaaaaaa aaagcctgca tgctggacat atatggtata attatttttt 2950

 cctttttttt tccttttggc ttggaaatgg acgttcgaag acttatagca 3000

 tggcattcat acttttgttt tattgcctca tgactttttt gagtttagaa 3050

 caaaacagtg caaccgtaga gccttcttcc catgaaattt tgcatctgct 3100

 ccaaaactgc tttgagttac tcagaacttc aacctcccaa tgcactgaag 3150

 gcattccttg tcaaagatac cagaatgggt tacacattta acctggcaaa 3200

 cattgaagaa ctcttaatgt tttcttttta ataagaatga cgcccacttt 3250

 ggggactaaa attgtgctat tgccgagaag cagtctaaaa tttatttttn 3300

 aaaaagagaa actgccccat tatttttggt ttgttttatt tttattttat 3350

 attttttggc ttttggtcat tgtcaaatgt ggaatgctct gggtttctag 3400

 tatataattt aattctagtg tttataatct gttagcccag ttaaaatgta 3450

 tgctacagat aaaggaatgt tatagataaa tttgaaagag ttaggtctgt 3500

 ttagctgtag attttttaaa cgattgatgc actaaattgt ttactattgt 3550

 gatgttaagg ggggtagagt ttgcaagggg actgtttaaa aaaagtagct 3600

 tatacagcat gtgcttgcaa cttaaatata agttgggtat gtgtagtctt 3650

 tgctatacca ctgactgtat tgaaaaccaa agtattaaga ggggaaacgc 3700

 ccctgtttat atctgtaggg gtattttaca ttcaaaaatg tatgtttttt 3750

 tttcttttca aaattaaagt atttgggact gaattgcact aagatataac 3800

 ctgcaagcat ataatacaaa aaaaaattgc aaaactgttt agaacgctaa 3850

 taaaatttat gcagttataa aaatggcatt actgcacagt tttaagatga 3900

 tgcagatttt tttacagttg tattgtggtg cagaactgga ttttctgtaa 3950

 cttaaaaaaa atccacagtt ttaaaggcaa taatcagtaa atgttatttt 4000

 cagggactac atcctgtctt taaaaagaaa tgaaaagtaa atcttaccac 4050

 aataaatata aaaaaatctt gtcagttact tttcttttac atattttgct 4100

 gtgcaaaatt gttttatatc ttgagttact aactaaccac gcgtgttgtt 4150

 cctatgtgct tttctttcat tttcaattct ggttatatca agaaaagata 4200

 atctacaata ataaacggca tttttttttg attctgtaaa aaaaaa 4246

<210> 1999
<211> 373
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3300
<223> Unknown amino acid

<400> 1999
 Met Ala Ser Glu Leu Ala Met Ser Asn Ser Asp Leu Pro Thr Ser
   1               5                  10                  15

 Pro Leu Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Met Lys Phe
                  20                  25                  30

 Glu Val Lys Lys Glu Pro Val Glu Thr Asp Arg Ile Ile Ser Gln
                  35                  40                  45

 Cys Gly Arg Leu Ile Ala Gly Gly Ser Leu Ser Ser Thr Pro Met
                  50                  55                  60

 Ser Thr Pro Cys Ser Ser Val Pro Pro Ser Pro Ser Phe Ser Ala
                  65                  70                  75

 Pro Ser Pro Gly Ser Gly Ser Glu Gln Lys Ala His Leu Glu Asp
                  80                  85                  90

 Tyr Tyr Trp Met Thr Gly Tyr Pro Gln Gln Leu Asn Pro Glu Ala
                  95                 100                 105

 Leu Gly Phe Ser Pro Glu Asp Ala Val Glu Ala Leu Ile Ser Asn
                 110                 115                 120

 Ser His Gln Leu Gln Gly Gly Phe Asp Gly Tyr Ala Arg Gly Ala
                 125                 130                 135

 Gln Gln Leu Ala Ala Ala Ala Gly Ala Gly Ala Gly Ala Ser Leu
                 140                 145                 150

 Gly Gly Ser Gly Glu Glu Met Gly Pro Ala Ala Ala Val Val Ser
                 155                 160                 165

 Ala Val Ile Ala Ala Ala Ala Ala Gln Ser Gly Ala Gly Pro His
                 170                 175                 180

 Tyr His His His His His His Ala Ala Gly His His His His Pro
                 185                 190                 195

 Thr Ala Gly Ala Pro Gly Ala Ala Gly Ser Ala Ala Ala Ser Ala
                 200                 205                 210

 Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Pro Ala Ser Ala Gly
                 215                 220                 225

 Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala
                 230                 235                 240

 Gly Ala Gly Gly Ala Leu His Pro His His Ala Ala Gly Gly Leu
                 245                 250                 255

 His Phe Asp Asp Arg Phe Ser Asp Glu Gln Leu Val Thr Met Ser
                 260                 265                 270

 Val Arg Glu Leu Asn Arg Gln Leu Arg Gly Val Ser Lys Glu Glu
                 275                 280                 285

 Val Ile Arg Leu Lys Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly
                 290                 295                 300

 Tyr Ala Gln Ser Cys Arg Phe Lys Arg Val Gln Gln Arg His Val
                 305                 310                 315

 Leu Glu Ser Glu Lys Asn Gln Leu Leu Gln Gln Val Asp His Leu
                 320                 325                 330

 Lys Gln Glu Ile Ser Arg Leu Val Arg Glu Arg Asp Ala Tyr Lys
                 335                 340                 345

 Glu Lys Tyr Glu Lys Leu Val Ser Ser Gly Phe Arg Glu Asn Gly
                 350                 355                 360

 Ser Ser Ser Asp Asn Pro Ser Ser Pro Glu Phe Phe Met
                 365                 370

<210> 2000
<211> 1919
<212> DNA
<213> Homo sapien

<400> 2000
 gtcctgccga gctgtgaggg caacggaggg gaaataaaag ggaacggctc 50

 cgaatctgcc ccagcggccg ctgcgagacc tcggcgccga catcgcgaca 100

 gcgaagcgct ttgcacgcca ggaaggtccc ctctatgtgc tgctgagccg 150

 gtcctggacg cgacgagccc gccctcggtc ttcggagcag aaatcgcaaa 200

 aacggaagga ctggaaatgg cagaccatat gatggccatg aaccacgggc 250

 gcttccccga cggcaccaat gggctgcacc atcaccctgc ccaccgcatg 300

 ggcatggggc agttcccgag cccccatcac caccagcagc agcagcccca 350

 gcacgccttc aacgccctaa tgggcgagca catacactac ggcgcgggca 400

 acatgaatgc cacgagcggc atcaggcatg cgatggggcc ggggactgtg 450

 aacggagggc accccccgag cgcgctggcc cccgcggcca ggtttaacaa 500

 ctcccagttc atgggtcccc cggtggccag ccagggaggc tccctgccgg 550

 ccagcatgca gctgcagaag ctcaacaacc agtatttcaa ccatcacccc 600

 tacccccaca accactacat gccggatttg caccctgctg caggccacca 650

 gatgaacggg acaaaccagc acttccgaga ttgcaacccc aagcacagcg 700

 gcggcagcag cacccccggc ggctcgggcg gcagcagcac ccccggcggc 750

 tctggcagca gctcgggcgg cggcgcgggc agcagcaaca gcggcggcgg 800

 cagcggcagc ggcaacatgc ccgcctccgt ggcccacgtc cccgctgcaa 850

 tgctgccgcc caatgtcata gacactgatt tcatcgacga ggaagttctt 900

 atgtccttgg tgatagaaat gggtttggac cgcatcaagg agctgcccga 950

 actctggctg gggcaaaacg agtttgattt tatgacggac ttcgtgtgca 1000

 aacagcagcc cagcagagtg agctgttgac tcgatcgaaa ccccggcgaa 1050

 agaaatcaaa cccccaactt cttcggcgtg aattaaaaga aacattccct 1100

 tagacacagt atctcacttt tcagatcttg aaaggtttga gaacttggaa 1150

 acaaagtaaa ctataaactt gtacaaattg gttttaaaaa aaattgctgc 1200

 cacttttttt tcctgttttt gtttcgtttt tgtagccttg acattcaccc 1250

 acctccctta tgtagttgaa atatctagct aacttggtct ttttcgttgt 1300

 ttgtttttac tcctttccct cactttctcc agtgctcaac tgttagatat 1350

 taatcttggc aaactgctta atcttgtgga ttttgtagat ggtttcaaat 1400

 gactgaactg cattcagatt tacgagtgaa aggaaaaatt gcattagttg 1450

 gttgcatgaa ctttgaaggg cagatattac tgcacaaact gccatctcgc 1500

 ttcatttttt taactatgca tttgagtaca gactaatttt taaaatatgc 1550

 taaactggaa gattaaacag atgtggccca aactgttctg gatcaggaaa 1600

 gtcatactgt tcactttcaa gttggctgtc ccccccgccg ccccccccca 1650

 cccccatatg tacagatgat aatagggtgt ggaatgtcgt cagtggcaaa 1700

 catttcacag attattttgt ttctgtcttc aacatttttg acactgtgct 1750

 aatagttata ttcagtacat gaaaagatac tactgtgttg aaagcctttt 1800

 aggaaatttt gacagtattt ttgtacaaaa catttttttg aaaaaatact 1850

 tgttaattta ttctatttta atttgccaat gtcaataaaa agttaagaaa 1900

 taaaaaaaaa aaaaaaaaa 1919

<210> 2001
<211> 270
<212> PRT
<213> Homo sapien

<400> 2001
 Met Ala Asp His Met Met Ala Met Asn His Gly Arg Phe Pro Asp
   1               5                  10                  15

 Gly Thr Asn Gly Leu His His His Pro Ala His Arg Met Gly Met
                  20                  25                  30

 Gly Gln Phe Pro Ser Pro His His His Gln Gln Gln Gln Pro Gln
                  35                  40                  45

 His Ala Phe Asn Ala Leu Met Gly Glu His Ile His Tyr Gly Ala
                  50                  55                  60

 Gly Asn Met Asn Ala Thr Ser Gly Ile Arg His Ala Met Gly Pro
                  65                  70                  75

 Gly Thr Val Asn Gly Gly His Pro Pro Ser Ala Leu Ala Pro Ala
                  80                  85                  90

 Ala Arg Phe Asn Asn Ser Gln Phe Met Gly Pro Pro Val Ala Ser
                  95                 100                 105

 Gln Gly Gly Ser Leu Pro Ala Ser Met Gln Leu Gln Lys Leu Asn
                 110                 115                 120

 Asn Gln Tyr Phe Asn His His Pro Tyr Pro His Asn His Tyr Met
                 125                 130                 135

 Pro Asp Leu His Pro Ala Ala Gly His Gln Met Asn Gly Thr Asn
                 140                 145                 150

 Gln His Phe Arg Asp Cys Asn Pro Lys His Ser Gly Gly Ser Ser
                 155                 160                 165

 Thr Pro Gly Gly Ser Gly Gly Ser Ser Thr Pro Gly Gly Ser Gly
                 170                 175                 180

 Ser Ser Ser Gly Gly Gly Ala Gly Ser Ser Asn Ser Gly Gly Gly
                 185                 190                 195

 Ser Gly Ser Gly Asn Met Pro Ala Ser Val Ala His Val Pro Ala
                 200                 205                 210

 Ala Met Leu Pro Pro Asn Val Ile Asp Thr Asp Phe Ile Asp Glu
                 215                 220                 225

 Glu Val Leu Met Ser Leu Val Ile Glu Met Gly Leu Asp Arg Ile
                 230                 235                 240

 Lys Glu Leu Pro Glu Leu Trp Leu Gly Gln Asn Glu Phe Asp Phe
                 245                 250                 255

 Met Thr Asp Phe Val Cys Lys Gln Gln Pro Ser Arg Val Ser Cys
                 260                 265                 270

<210> 2002
<211> 6212
<212> DNA
<213> Homo sapien

<400> 2002
 ggaaagggga acagttaaat ttgtaatttg ggttgtgtga aaacttcttt 50

 gggcctcata aacaaccaca gaaccacaag ttgggtagcc tggcagtgtc 100

 agaagtctga acccagcata gtggtcagca ggcaggacga atcacactga 150

 atgcaaacca cagggtttcg cagcgtggtg agcatcacca acccacagcc 200

 aaggcggcgc tggctttttt ttttttttaa tctttaacaa tttgaatatt 250

 tgtttttaca aaggtgcatt ttttaatagg gcttggggag tcccagaggt 300

 atccagcaga ggggagaaga aagagagatg tagggctaga ggggtgaggc 350

 tgaaacagtg acctgtcttg gttttcgctc cgaaggtaaa agaaatcatt 400

 gagtcccccg ccttcagaag agggtgcatt ttcaggagga agcgatggct 450

 tcagacagca tatttgagtc atttccttcg tacccacagt gcttcatgag 500

 agaatgcata cttggaatga atccttctag agacgtccac gatgccagca 550

 cgagccgccg cttcacgccg ccttccaccg cgctgagccc aggcaagatg 600

 agcgaggcgt tgccgctggg cgccccggac gccggcgctg ccctggccgg 650

 caagctgagg agcggcgacc gcagcatggt ggaggtgctg gccgaccacc 700

 cgggcgagct ggtgcgcacc gacagcccca acttcctctg ctccgtgctg 750

 cctacgcact ggcgctgcaa caagaccctg cccatcgctt tcaaggtggt 800

 ggccctaggg gatgttccag atggcactct ggtcactgtg atggctggca 850

 atgatgaaaa ctactcggct gagctgagaa atgctaccgc agccatgaag 900

 aaccaggttg caagatttaa tgacctcagg tttgtcggtc gaagtggaag 950

 agggaaaagc ttcactctga ccatcactgt cttcacaaac ccaccgcaag 1000

 tcgccaccta ccacagagcc atcaaaatca cagtggatgg gccccgagaa 1050

 cctcgaagac atcggcagaa actagatgat cagaccaagc ccgggagctt 1100

 gtccttttcc gagcggctca gtgaactgga gcagctgcgg cgcacagcca 1150

 tgagggtcag cccacaccac ccagccccca cgcccaaccc tcgtgcctcc 1200

 ctgaaccact ccactgcctt taaccctcag cctcagagtc agatgcagga 1250

 tacaaggcag atccaaccat ccccaccgtg gtcctacgat cagtcctacc 1300

 aatacctggg atccattgcc tctccttctg tgcacccagc aacgcccatt 1350

 tcacctggac gtgccagcgg catgacaacc ctctctgcag aactttccag 1400

 tcgactctca acggcacccg acctgacagc gttcagcgac ccgcgccagt 1450

 tccccgcgct gccctccatc tccgaccccc gcatgcacta tccaggcgcc 1500

 ttcacctact ccccgacgcc ggtcacctcg ggcatcggca tcggcatgtc 1550

 ggccatgggc tcggccacgc gctaccacac ctacctgccg ccgccctacc 1600

 ccggctcgtc gcaagcgcag ggaggcccgt tccaagccag ctcgccctcc 1650

 taccacctgt actacggcgc ctcggccggc tcctaccagt tctccatggt 1700

 gggcggcgag cgctcgccgc cgcgcatcct gccgccctgc accaacgcct 1750

 ccaccggctc cgcgctgctc aaccccagcc tcccgaacca gagcgacgtg 1800

 gtggaggccg agggcagcca cagcaactcc cccaccaaca tggcgccctc 1850

 cgcgcgcctg gaggaggccg tgtggaggcc ctactgaggc gccaggcctg 1900

 gcccggctgg gccacgcggg ccgccgcctt cgcctccggg cgcgcgggcc 1950

 tcctgttcgc gacaagcccg ccgggatccc gggccctggg cccggccacc 2000

 gtcctggggc cgagggcgcc cgacggccag gatctcgctg taggtcaggc 2050

 ccgcgcagcc tcctgcgccc agaagcccac gccgccgccg tctgctggcg 2100

 ccccggccct cgcggaggtg tccgaggcga cgcacctcga gggtgtccgc 2150

 cggccccagc acccagggga cgcgctggaa agcaaacagg aagattcccg 2200

 gagggaaact gtgaatgctt ctgatttagc aatgctgtga ataaaaagaa 2250

 agattttata cccttgactt aactttttaa ccaagttgtt tattccaaag 2300

 agtgtggaat tttggttggg gtggggggag aggagggatg caactcgccc 2350

 tgtttggcat ctaattctta tttttaattt ttccgcacct tatcaattgc 2400

 aaaatgcgta tttgcatttg ggtggttttt atttttatat acgtttatat 2450

 aaatatatat aaattgagct tgcttctttc ttgctttgac catggaaaga 2500

 aatatgattc ccttttcttt aagttttatt taacttttct tttggacttt 2550

 tgggtagttg tttttttttg ttttgttttg tttttttgag aaacagctac 2600

 agctttgggt catttttaac tactgtattc ccacaaggaa tccccagata 2650

 tttatgtatc ttgatgttca gacatttatg tgttgataat tttttaatta 2700

 tttaaatgta cttatattaa gaaaaatatc aagtactaca ttttcttttg 2750

 ttcttgatag tagccaaagt taaatgtatc acattgaaga aggctagaaa 2800

 aaaagaatga gtaatgtgat cgcttggtta tccagaagta ttgtttacat 2850

 taaactccct ttcatgttaa tcaaacaagt gagtagctca cgcagcaacg 2900

 tttttaatag gatttttaga cactgagggt cactccaagg atcagaagta 2950

 tggaattttc tgccaggctc aacaagggtc tcatatctaa cttcctcctt 3000

 aaaacagaga aggtcaatct agttccagag ggttgaggcg ggtgccaata 3050

 attacatctt tggagaggat ttgatttctg cccagggatt tgctcacccc 3100

 aaggtcatct gataatttca cagatgctgt gtaacagaac acagccaaag 3150

 taaactgtgt aggggagcca catttacata ggaaccaaat caatgaattt 3200

 aggggttacg attatagcaa tttaagggcc accagaagca ggcctcgagg 3250

 agtcaatttg cctctgtgtg cctcagtgga gacaagtggg aaaacatggt 3300

 cccacctgtg cgagaccccc tgtcctgtgc tgctcactca acaacatctt 3350

 tgtgttgctt tcaccaggct gagaccctac cctatggggt atatgggctt 3400

 ttacctgtgc accagtgtga caggaaagat tcatgtcact actgtccgtg 3450

 gctacaattc aaaggtatcc aatgtcgctg taaattttat ggcactattt 3500

 ttattggagg atttggtcag aatgcagttg ttgtacaact cataaatact 3550

 aactgctgat tttgacacat gtgtgctcca aatgatctgg tggttattta 3600

 acgtacctct taaaattcgt tgaaacgatt tcaggtcaac tctgaagagt 3650

 atttgaaagc aggacttcag aacagtgttt gatttttatt ttataaattt 3700

 aagcattcaa attaggcaaa tctttggctg caggcagcaa aaacagctgg 3750

 acttatttaa aacaacttgt ttttgagttt tcttatatat atattgatta 3800

 tttgttttac acacatgcag tagcactttg gtaagagtta aagagtaaag 3850

 cagcttatgt tgtcaggtcg ttcttatcta gagaagagct atagcagatc 3900

 tcggacaaac tcagaatata ttcactttca tttttgacag gattccctcc 3950

 acaactcagt ttcatatatt attccgtatt acatttttgc agctaaatta 4000

 ccataaaatg tcagcaaatg taaaaattta atttctgaaa agcaccatta 4050

 gcccatttcc cccaaattaa acgtaaatgt tttttttcag cacatgttac 4100

 catgtctgac ctgcaaaaat gctggagaaa aatgaaggaa aaaattatgt 4150

 ttttcagttt aattctgtta actgaagata ttccaactca aaaccagcct 4200

 catgctctga ttagataatc ttttacattg aacctttact ctcaaagcca 4250

 tgtgtggagg gggcttgtca ctattgtagg ctcactggat tggtcattta 4300

 gagtttcaca gactcttacc agcatatata gtatttaatt gtttcaaaaa 4350

 aaatcaaact gtagttgttt tggcgatagg tctcacgcaa cacatttttg 4400

 tatgtgtgtg tgtgtgcgtg tgtgtgtgtg tgtgtgaaaa attgcattca 4450

 ttgacttcag gtagattaag gtatcttttt attcattgcc ctcaggaaag 4500

 ttaaggtatc aatgagaccc ttaagccaat catgtaataa ctgcatgtgt 4550

 ctggtccagg agaagtattg aataagccat ttctactgct tactcatgtc 4600

 cctatttatg atttcaacat ggatacatat ttcagttctt tctttttctc 4650

 actatctgaa aatacatttc cctccctctc ttccccccaa tatctccctt 4700

 tttttctctc ttcctctatc ttccaaaccc cactttctcc ctcctccttt 4750

 tcctgtgttc tcttaagcag atagcacata cccccaccca gtaccaaatt 4800

 tcagaacaca agaaggtcca gttcttcccc cttcacataa aggaacatgg 4850

 tttgtcagcc tttctcctgt ttatgggttt cttccagcag aacagagaca 4900

 ttgccaacca tattggatct gcttgctgtc caaaccagca aacttcctgg 4950

 gcaaatcaca atcagtgagt aaatagacag cctttctgct gccttgggtt 5000

 tctgtgcaga taaacagaaa tgctctgatt agaaaggaaa tgaatggttc 5050

 cactcaaatg tcctgcaatt taggattgca gatttctgcc ttgaaatacc 5100

 tgtttctttg ggacattccg tcctgatgat ttttattttt gttggttttt 5150

 atttttgggg ggaatgacat gtttgggtct tttatacatg aaaatttgtt 5200

 tgacaataat ctcacaaaac atattttaca tctgaacaaa atgccttttt 5250

 gtttaccgta gcgtatacat ttgttttggg atttttgtgt gtttgttggg 5300

 aattttgttt ttagccaggt cagtattgat gaggctgatc atttggctct 5350

 ttttttcctt ccagaagagt tgcatcaaca aagttaattg tatttatgta 5400

 tgtaaataga ttttaagctt cattataaaa tattgttaat gcctataact 5450

 ttttttcaat ttttttgtgt gtgtttctaa ggactttttc ttaggtttgc 5500

 taaatactgt agggaaaaaa tgcttctttc taactttgtt tattttagac 5550

 tttaaaatga gctacttctt attcactttt gtaaacagct aatagcatgg 5600

 ttccaatttt ttttaagttc actttttttg ttctagggga aatgaatgtg 5650

 caaaaaaaga aaaagaactg ttggttattt gtgttattct ggatgtataa 5700

 aaatcaatgg aaaaaaataa actttcaaat tgaaatgacg gtataacaca 5750

 tctactgaaa aagcaacggg aaatgtggtc ctatttaagc cagcccccac 5800

 ctagggtcta tttgtgtggc agttattggg tttggtcaca aaacatcctg 5850

 aaaattcgtg cgtgggcttc tttctccctg gtacaaacgt atggaatgct 5900

 tcttaaaggg gaactgtcaa gctggtgtct tcagccagat gacatgagag 5950

 aatatcccag aaccctctct ccaaggtgtt tctagatagc acaggagagc 6000

 aggcactgca ctgtccacag tccacggtac acagtcgggt gggccgcctc 6050

 ccctctcctg ggagcattcg tcgtgcccag cctgagcagg gcagctggac 6100

 tgctgctgtt caggagccac cagagccttc ctctctttgt accacagttt 6150

 cttctgtaaa tccagtgtta caatcagtgt gaatggcaaa taaacagttt 6200

 gacaagtaca ta 6212

<210> 2003
<211> 480
<212> PRT
<213> Homo sapien

<400> 2003
 Met Ala Ser Asp Ser Ile Phe Glu Ser Phe Pro Ser Tyr Pro Gln
   1               5                  10                  15

 Cys Phe Met Arg Glu Cys Ile Leu Gly Met Asn Pro Ser Arg Asp
                  20                  25                  30

 Val His Asp Ala Ser Thr Ser Arg Arg Phe Thr Pro Pro Ser Thr
                  35                  40                  45

 Ala Leu Ser Pro Gly Lys Met Ser Glu Ala Leu Pro Leu Gly Ala
                  50                  55                  60

 Pro Asp Ala Gly Ala Ala Leu Ala Gly Lys Leu Arg Ser Gly Asp
                  65                  70                  75

 Arg Ser Met Val Glu Val Leu Ala Asp His Pro Gly Glu Leu Val
                  80                  85                  90

 Arg Thr Asp Ser Pro Asn Phe Leu Cys Ser Val Leu Pro Thr His
                  95                 100                 105

 Trp Arg Cys Asn Lys Thr Leu Pro Ile Ala Phe Lys Val Val Ala
                 110                 115                 120

 Leu Gly Asp Val Pro Asp Gly Thr Leu Val Thr Val Met Ala Gly
                 125                 130                 135

 Asn Asp Glu Asn Tyr Ser Ala Glu Leu Arg Asn Ala Thr Ala Ala
                 140                 145                 150

 Met Lys Asn Gln Val Ala Arg Phe Asn Asp Leu Arg Phe Val Gly
                 155                 160                 165

 Arg Ser Gly Arg Gly Lys Ser Phe Thr Leu Thr Ile Thr Val Phe
                 170                 175                 180

 Thr Asn Pro Pro Gln Val Ala Thr Tyr His Arg Ala Ile Lys Ile
                 185                 190                 195

 Thr Val Asp Gly Pro Arg Glu Pro Arg Arg His Arg Gln Lys Leu
                 200                 205                 210

 Asp Asp Gln Thr Lys Pro Gly Ser Leu Ser Phe Ser Glu Arg Leu
                 215                 220                 225

 Ser Glu Leu Glu Gln Leu Arg Arg Thr Ala Met Arg Val Ser Pro
                 230                 235                 240

 His His Pro Ala Pro Thr Pro Asn Pro Arg Ala Ser Leu Asn His
                 245                 250                 255

 Ser Thr Ala Phe Asn Pro Gln Pro Gln Ser Gln Met Gln Asp Thr
                 260                 265                 270

 Arg Gln Ile Gln Pro Ser Pro Pro Trp Ser Tyr Asp Gln Ser Tyr
                 275                 280                 285

 Gln Tyr Leu Gly Ser Ile Ala Ser Pro Ser Val His Pro Ala Thr
                 290                 295                 300

 Pro Ile Ser Pro Gly Arg Ala Ser Gly Met Thr Thr Leu Ser Ala
                 305                 310                 315

 Glu Leu Ser Ser Arg Leu Ser Thr Ala Pro Asp Leu Thr Ala Phe
                 320                 325                 330

 Ser Asp Pro Arg Gln Phe Pro Ala Leu Pro Ser Ile Ser Asp Pro
                 335                 340                 345

 Arg Met His Tyr Pro Gly Ala Phe Thr Tyr Ser Pro Thr Pro Val
                 350                 355                 360

 Thr Ser Gly Ile Gly Ile Gly Met Ser Ala Met Gly Ser Ala Thr
                 365                 370                 375

 Arg Tyr His Thr Tyr Leu Pro Pro Pro Tyr Pro Gly Ser Ser Gln
                 380                 385                 390

 Ala Gln Gly Gly Pro Phe Gln Ala Ser Ser Pro Ser Tyr His Leu
                 395                 400                 405

 Tyr Tyr Gly Ala Ser Ala Gly Ser Tyr Gln Phe Ser Met Val Gly
                 410                 415                 420

 Gly Glu Arg Ser Pro Pro Arg Ile Leu Pro Pro Cys Thr Asn Ala
                 425                 430                 435

 Ser Thr Gly Ser Ala Leu Leu Asn Pro Ser Leu Pro Asn Gln Ser
                 440                 445                 450

 Asp Val Val Glu Ala Glu Gly Ser His Ser Asn Ser Pro Thr Asn
                 455                 460                 465

 Met Ala Pro Ser Ala Arg Leu Glu Glu Ala Val Trp Arg Pro Tyr
                 470                 475                 480

<210> 2004
<211> 7248
<212> DNA
<213> Homo sapien

<400> 2004
 tactcaaaat tcacatgata aaataattga tcctgaaaaa cgtgttccta 50

 ctcaaggaat gtttgataaa aatgggataa agggaggttt gaaaagtgtt 100

 tctttattca catcaaagtt agcaaagcca tccactatgt ttgtgtcatc 150

 tacagaggag ttaaaccaaa agtctttttc tggaccatct aatttgggta 200

 aattcaccaa atgcacatta ttaggaagga cttcatattc ttcgatcaat 250

 actccaaaat cacagttgaa tggattttat ggaaaccgat cagctggtag 300

 catgcaaaag gcctagagcg aactcctgtg ccaccagaag cagttctgga 350

 gaaagcttag ctcaatcccc agacagtagt aaatctatta attgtgaaaa 400

 aatggtaagg tcacaaagtt tttcacattc cattcagaat tcattccttc 450

 caccttcatc tataaccagt cacattcctt tatagagctg tggatcttac 500

 aaagccttat cagaaccaac agctatccat tagagtgcct ctacggtcaa 550

 gtatgctaac aagaaattcc cggcagccag aagtactcaa tgggaatgaa 600

 catttggggt atggatttaa taggccttat gctgctggtg gaaagaagtt 650

 ggctttacca aatggcccag gtgtaacttc tactttaggt tatagaatgg 700

 ttcatccctc tctactgaaa tctagccgat ctccattttc tgggactatg 750

 acagttgatg gaaataaaaa ttcacctgct gacacatgtg tagaggaaga 800

 tgctacagtt ttggctaagg acagagctgc taataaggac caagaactga 850

 ttgaaaatga aagttataga acaaaaaaca accagaccat gaaacatgat 900

 gctaaaatga gatacctgag tgatgatgtg gatgacattt ccttgtcgtc 950

 tttgtcatct tctgataaga atgatttaag tgaagacttt agtgatgatt 1000

 ttatagatat agaagactcc aacagaacta gaataactcc agaggaaatg 1050

 tctctcaaag aagagaaaca tgaaaatggg ccaccacagg atatgtttga 1100

 ttcccccaag gaaaatgaaa aagccttcag taaaactgat gaatggatag 1150

 atataagtgt ctctgacagg agtgaatgta caaaacatac ttctgggaat 1200

 aatttggttt caccagatac agactacaga gctggttctt cgtttgaact 1250

 ctctccatct gatagctctg atggaacata catgtgggat gaagaaggct 1300

 tggaacccat tggaaatgtc catccagttg ggagctatga gtcctctgaa 1350

 atgaacagca tagatatttt gaataatctt gaatcatgtg accttgagga 1400

 tgatgatctt atgcttgatg tggatctgcc tgaggatgca cctcttgaaa 1450

 atgtggagtg tgacaatatg aaccgctttg accgaccaga cagaaatgtt 1500

 cggcagcctc aggaaggttt ttggaaaagg ccaccccaga ggtggagtgg 1550

 acaggagcat taccacctca gccaccctga ccactatcat caccatggaa 1600

 aaagtgactt gagcagaggc tctccctata gagaatctcc tttgggtcat 1650

 tttgaaagct atggagggat gccctttttc caggctcaga agatgtttgt 1700

 tgatgtacca gaaaatacag tgatactgga tgagatgacc cttcggcaca 1750

 tggttcagga ttgcactgct gtaaaaactc agttactcaa actgaaacgt 1800

 ctcctgcatc agcatgatgg aagtggttca ttgcatgata ttcaactgtc 1850

 attgccatcc agtccagaac cagaagatgg tgataaagta tataagaatg 1900

 aagatttatt aaatgaaata aaacaactta aagacgaaat aaagaaaaaa 1950

 gatgaaaaga tccaactatt agaacttcag cttgcaactc agcatatctg 2000

 ccaccaaaaa tgtaaagagg aaaaatgcac ttatgctgat aaatataccc 2050

 aaacaccctg gagacgaatt cctggtgggt attctgctcc ctccttctct 2100

 ccttggcagg gctccttcca ggggatccca cggactgttc caccgcaccg 2150

 cagacagacc tcaagtacta cagccttcca gcagccttcc cagacccaca 2200

 gatcacaccc agggaaaact aataaagcca caacgtatcg aggcccgcag 2250

 tgaatgctca atccaagaca tgcatcaggg cggtgcacat ccggaagaaa 2300

 gctttacaca cgtcttgcac caagaaagca actatggttt ggaagagcag 2350

 cctttttcat caggcccaca attaacaatg gatgtggcta agagtacacc 2400

 ttctgaagca aacttaaaca ttactgtaaa tgctcaagag ccttatcatt 2450

 tggcaaacaa tcaaattagt gacatgcagt ttatacccac ttctcttcag 2500

 acacctcccg agtcaagtac agtagaccag gctaagagag ttggaagaaa 2550

 tcagtctccg ccagtgggtt atatgtctca gcccaagtcc ttgcagcttt 2600

 taaagccatc catattgagt tctttggtac cgcctccagt ttctgaatca 2650

 tctccaagta ggactcccac ttgtaaaaag tcaccaataa tcacaacatg 2700

 taattcagca aaacttcagc caacatctag tcaaacaaat cttgcaaata 2750

 atcagaatct gaaagcatct aagctccgcc ccccctcagg ctctttcaaa 2800

 caaaaacaaa caaacagccc ccaactagag cctcaaagct tccaggccaa 2850

 gacaagcatc ccaaggccac taacacaacg aaaagaaatc atgcagaatc 2900

 caaatggcaa tttgcattct ggggattgtt tggcctctaa tcgatattct 2950

 cgtcttccta aaccaaagat acattaagta catagccatc acctgccaat 3000

 ttgtttctta aaaacaatct cttctgtaat agctttatgt gcagcttgca 3050

 gcttgctact gtggtggagg ttccattgaa agcctgcaaa tcttaaatta 3100

 aaatgtggaa gcttctacta gtttggctcc ttcattttat atcctggttg 3150

 aagtacatgc catttgagca taattatctc aggtaaacac gaaagtttgc 3200

 ttacccattt cagaggcctg ccaaaggccc aaatcatgtt atccatccct 3250

 ctccaggtca gaaaattcat aatattttac tgagcaggca agaagtgtgc 3300

 tttgctggtt tagtcctatt aaggtctgta tttattgtgg ttgtcagaac 3350

 ctcacccctt ttcacttgtc tctcctgtga atatggctac tattttaact 3400

 aaagatatgg tgataatgga agatggtagt ctgtaagcag agttctggcc 3450

 agtgttttgt atatttaaaa ggtctatgca aaagctttgt gatgaataaa 3500

 ggagattagg cttttaatgg aaagtctatg taagttttat ttttccttgc 3550

 cagggtcagt cagctaatgt tactgttgat tcatttccca aattccccag 3600

 actgaaaatg tttcttatta catataaatc agttatatat tcctttacat 3650

 cttgttttac aaacacatgt gcatgcacac acacacatac acacacatac 3700

 catttatgtt tgtatttgtt actgggtaaa ttttggagcg cttgagatac 3750

 accttgaaac ctgtacctaa agatgtattc atttgtaaca tatgttggtg 3800

 ctagagtttt gctggtaatt caggtttgaa cccttaggct tgtggatcca 3850

 tgatagccat tttaaggttc cacagcatta tgtctttaat tgtaatattt 3900

 atatttattg attttctgct aatatctgaa gactgaaata atgaacttga 3950

 aacatttgca caaaactttg atggggtata aatataccat atatagggat 4000

 tgtaaactat tttctatagc aaaacaagtt aaaatatttt gagaaaaata 4050

 acaaatttaa ataagactat cttgagaaag ctggagttca taatattctc 4100

 cccctccccc atctccagtc tcctaggttt cccttttctg tgttttttgt 4150

 ttttttctgt ttgttttttg agacagagtc ttgctccatt gcccaggctg 4200

 gattacagtg gcgcaatctc ggctcactgc aacttctgcc tcccgggttc 4250

 aagcgattct cctgcctcag cctcctgagt agctgggact acaggcatgt 4300

 gccaccatgc ctggctaatt tttttgtatt tttagtagag atgaggtttc 4350

 accttgttgg tcaggctggt ctcgaactcc tgacctcaag tgatccaccc 4400

 acctcgtcta tggtgtattt ttgaaagaca attttttaaa ggtagatttg 4450

 ggaaaaaaat agaattgaag atgggaaatt ttgttttatt aaaaaggtgc 4500

 tagaagatgt ttcaaagaca atattcttat tttaatacgc tgtagaaggt 4550

 aggtgtggaa cctccatgct accatgtgca caaacctaat tatgctttgg 4600

 gtcacttgtc agttcagtaa atctgccttc ctcttctccc aaatcatgtc 4650

 atctttaggt tgttcacctg cagctgcttt aaatgaatta gtatctttca 4700

 gatagataac cttacaagga gaatgtttgt tttgagcagc tgaccaaaaa 4750

 tatatcaaac aggattatgg ccaaaaagtc actcaaattt ctagagattc 4800

 ctttaaaaga tgtatgttga tgaaattgcc cctttataag aaaaacaaca 4850

 gcaagtcttt tagtagaaat ttgaaagaag tgtttgctac cattttgacc 4900

 cattattccc ttacctatca gatgaatttg ccattcactg gatagaaacc 4950

 attcttggat ttggtaagag gtgagcaaga caaatcttgt accatactct 5000

 tatgtaccag cacttctgat ggagaagcag tgaagttcag aacgttcttc 5050

 acatagtcca gatactgtta gagtcaggca aatcagcaaa gcactttgtt 5100

 atggagatga cccatgatgg ctgcagttgt aagtgggcat acatgttcta 5150

 tcattttgaa ggagaaagaa aaccgttctc acatgtcgca aatatgtgaa 5200

 tcatactata ttcccctaaa gtaaaaccag tgacttagtg gtttttggtt 5250

 tatttagaag ttggtttaga cccttatgaa acattattta cgagttggcc 5300

 ttatccttaa gggaaaagtt ctaaattttt aaatttattt ttaattccct 5350

 agtctgaggg aaatgtcttt attgtccatt acataaaaat gttgactcca 5400

 gtaatttatt tttctctatt ttttcctcca tgtatttact ccatttttct 5450

 ctattttttc cttccctgat ggatttgcag aaatgttaac caattagctc 5500

 aacttttctc tacctttgtt gagtcttaat cttttagaag ataggcttac 5550

 cgtatattta tgaagcataa tatattaaaa gaaaacaaat ctaggatgct 5600

 tgcatgacat aaagtatttg cctgcagttt tcattaaaaa ctgcaagaat 5650

 atcatgcttg tctgcttctt agtaaatgtt aagtctgaaa tggaagtgag 5700

 gatgtaactc tactgaataa tcaaagatca tcttagattt ggcttgatct 5750

 gtgtttattg cttctattaa tgtaaatcaa ctctgtgcca aatcctcctc 5800

 cacaaaccat ttattgtctt agttctagtg gtatcaatga agatagttac 5850

 agtatatgaa ttctaagtcc tgaggaagaa attttatggg gtttgttaag 5900

 tttcacattc gtgaaagagg aaattagtag agtattcaga ctttgatatt 5950

 tggctgttaa tgggatgcat atcaaatttt taaaagaagg cttggcctaa 6000

 ggagtttatt ggtacaggtg cagatgattt taaggcatta aaggattata 6050

 gagttatgtc atttgagact gtttctaata actgagacca tctaacattt 6100

 ttcttttgga gtctcatttt tatttgtgca atattttcag gcatataggc 6150

 tactgttcat tgtatttata tatatattag aatttactaa gtactttaac 6200

 aagtaaaaat ctgaatatga aagaaaatat cagatttgca ctttaaatga 6250

 gcttaattgc ttgaagttgt gcctgaaata tcgaattgcc tcctattggg 6300

 tgtggctttg ttgaaataaa tttgtaattg ttgctgtttg aagatatcag 6350

 tacagctgtt cacagaaata tattcccagc atgtcacttt tccattaaag 6400

 cactaagttt tctttgaatg ttccattgtt ccgataagta ttttactttt 6450

 ttctcagtac atcagagaga gcgtgatccc cctacagctg tcacttccaa 6500

 atgttcctgt agcataaatg gtgttacaga cactgaggtg cactcttggt 6550

 ttctgagcag agttgtcata ctggtttcct ggctctaggg cactggggat 6600

 gtactttgaa atcaccgaac aggcttgcaa ttaagatcaa taaggctgca 6650

 gcaccatttc aatttacttt ccatcttacc cagtagtttt tgtgttttta 6700

 aattcgtttg ggtggttatg tttgcatgct taagcacaca tttgaaaatt 6750

 aattatagct gtactacccg atgtttttcc ttggggatga tggccttgtt 6800

 cctttttaaa ttctgatgct tgaattctat tttctagtga tttttcacat 6850

 ctccctttaa gtttttgctg cagcaatttg agagagtact tttgattaaa 6900

 tgattctgat ggtgggcacc aatctacaac tatgtcatta actgaagata 6950

 catgttttaa tcttgttggg aataagctta cccactttct ccttggtaaa 7000

 gcgtttactt aacaaaataa tacccgagaa tgtaaggtct ctaagtcatt 7050

 actaacaaag agcaaaaata atatctgcag tattgttttt cccattgatt 7100

 ttaagtcagt ttagagtaca aactgtatat tagaatttgc ctgtaaaatg 7150

 aattctaaaa agcagatgta aagtctctcc tgaaaatgtt ggcatagtaa 7200

 ataaaaataa agttcataat tataaagtaa aaaaaaaaaa aaaaaaaa 7248

<210> 2005
<211> 566
<212> PRT
<213> Homo sapien

<400> 2005
 Met Leu Thr Arg Asn Ser Arg Gln Pro Glu Val Leu Asn Gly Asn
   1               5                  10                  15

 Glu His Leu Gly Tyr Gly Phe Asn Arg Pro Tyr Ala Ala Gly Gly
                  20                  25                  30

 Lys Lys Leu Ala Leu Pro Asn Gly Pro Gly Val Thr Ser Thr Leu
                  35                  40                  45

 Gly Tyr Arg Met Val His Pro Ser Leu Leu Lys Ser Ser Arg Ser
                  50                  55                  60

 Pro Phe Ser Gly Thr Met Thr Val Asp Gly Asn Lys Asn Ser Pro
                  65                  70                  75

 Ala Asp Thr Cys Val Glu Glu Asp Ala Thr Val Leu Ala Lys Asp
                  80                  85                  90

 Arg Ala Ala Asn Lys Asp Gln Glu Leu Ile Glu Asn Glu Ser Tyr
                  95                 100                 105

 Arg Thr Lys Asn Asn Gln Thr Met Lys His Asp Ala Lys Met Arg
                 110                 115                 120

 Tyr Leu Ser Asp Asp Val Asp Asp Ile Ser Leu Ser Ser Leu Ser
                 125                 130                 135

 Ser Ser Asp Lys Asn Asp Leu Ser Glu Asp Phe Ser Asp Asp Phe
                 140                 145                 150

 Ile Asp Ile Glu Asp Ser Asn Arg Thr Arg Ile Thr Pro Glu Glu
                 155                 160                 165

 Met Ser Leu Lys Glu Glu Lys His Glu Asn Gly Pro Pro Gln Asp
                 170                 175                 180

 Met Phe Asp Ser Pro Lys Glu Asn Glu Lys Ala Phe Ser Lys Thr
                 185                 190                 195

 Asp Glu Trp Ile Asp Ile Ser Val Ser Asp Arg Ser Glu Cys Thr
                 200                 205                 210

 Lys His Thr Ser Gly Asn Asn Leu Val Ser Pro Asp Thr Asp Tyr
                 215                 220                 225

 Arg Ala Gly Ser Ser Phe Glu Leu Ser Pro Ser Asp Ser Ser Asp
                 230                 235                 240

 Gly Thr Tyr Met Trp Asp Glu Glu Gly Leu Glu Pro Ile Gly Asn
                 245                 250                 255

 Val His Pro Val Gly Ser Tyr Glu Ser Ser Glu Met Asn Ser Ile
                 260                 265                 270

 Asp Ile Leu Asn Asn Leu Glu Ser Cys Asp Leu Glu Asp Asp Asp
                 275                 280                 285

 Leu Met Leu Asp Val Asp Leu Pro Glu Asp Ala Pro Leu Glu Asn
                 290                 295                 300

 Val Glu Cys Asp Asn Met Asn Arg Phe Asp Arg Pro Asp Arg Asn
                 305                 310                 315

 Val Arg Gln Pro Gln Glu Gly Phe Trp Lys Arg Pro Pro Gln Arg
                 320                 325                 330

 Trp Ser Gly Gln Glu His Tyr His Leu Ser His Pro Asp His Tyr
                 335                 340                 345

 His His His Gly Lys Ser Asp Leu Ser Arg Gly Ser Pro Tyr Arg
                 350                 355                 360

 Glu Ser Pro Leu Gly His Phe Glu Ser Tyr Gly Gly Met Pro Phe
                 365                 370                 375

 Phe Gln Ala Gln Lys Met Phe Val Asp Val Pro Glu Asn Thr Val
                 380                 385                 390

 Ile Leu Asp Glu Met Thr Leu Arg His Met Val Gln Asp Cys Thr
                 395                 400                 405

 Ala Val Lys Thr Gln Leu Leu Lys Leu Lys Arg Leu Leu His Gln
                 410                 415                 420

 His Asp Gly Ser Gly Ser Leu His Asp Ile Gln Leu Ser Leu Pro
                 425                 430                 435

 Ser Ser Pro Glu Pro Glu Asp Gly Asp Lys Val Tyr Lys Asn Glu
                 440                 445                 450

 Asp Leu Leu Asn Glu Ile Lys Gln Leu Lys Asp Glu Ile Lys Lys
                 455                 460                 465

 Lys Asp Glu Lys Ile Gln Leu Leu Glu Leu Gln Leu Ala Thr Gln
                 470                 475                 480

 His Ile Cys His Gln Lys Cys Lys Glu Glu Lys Cys Thr Tyr Ala
                 485                 490                 495

 Asp Lys Tyr Thr Gln Thr Pro Trp Arg Arg Ile Pro Gly Gly Tyr
                 500                 505                 510

 Ser Ala Pro Ser Phe Ser Pro Trp Gln Gly Ser Phe Gln Gly Ile
                 515                 520                 525

 Pro Arg Thr Val Pro Pro His Arg Arg Gln Thr Ser Ser Thr Thr
                 530                 535                 540

 Ala Phe Gln Gln Pro Ser Gln Thr His Arg Ser His Pro Gly Lys
                 545                 550                 555

 Thr Asn Lys Ala Thr Thr Tyr Arg Gly Pro Gln
                 560                 565

<210> 2006
<211> 3231
<212> DNA
<213> Homo sapien

<400> 2006
 cgtgaaggca aagagaacac gctgcaaaag gcttccaaga atcctcgaca 50

 tggcaaggag gagctcgttc cagtcgtgtc agataatatc cctgttcact 100

 tttgccgttg gagtcagtat ctgcttagga ttcactgcac atcgaattaa 150

 gagagcagaa ggatgggagg aaggtcctcc tacagtgcta tcagactccc 200

 cctggaccaa catctccgga tcttgcaagg gcaggtgctt tgaacttcaa 250

 gaggctggac ctcctgattg tcgctgtgac aacttgtgta agagctatac 300

 cagttgctgc catgactttg atgagctgtg tttgaagaca gcccgtggct 350

 gggagtgtac taaggacaga tgtggagaag tcagaaatga agaaaatgcc 400

 tgtcactgct cagaggactg cttggccagg ggagactgct gtaccaatta 450

 ccaagtggtt tgcaaaggag agtcgcattg ggttgatgat gactgtgagg 500

 aaataaaggc cgcagaatgc cctgcagggt ttgttcgccc tccattaatc 550

 atcttctccg tggatggctt ccgtgcatca tacatgaaga aaggcagcaa 600

 agtcatgcct aatattgaaa aactaaggtc ttgtggcaca cactctccct 650

 acatgaggcc ggtgtaccca actaaaacct ttcctaactt atacactttg 700

 gccactgggc tatatccaga atcacatgga attgttggca attcaatgta 750

 tgatcctgta tttgatgcca cttttcatct gcgagggcga gagaaattta 800

 atcatagatg gtggggaggt caaccgctat ggattacagc caccaagcaa 850

 ggggtgaaag ctggaacatt cttttggtct gttgtcatcc ctcacgagcg 900

 gagaatatta accatattgc ggtggctcac cctgccagat catgagaggc 950

 cttcggtcta tgccttctat tctgagcaac ctgatttctc tggacacaaa 1000

 tatggccctt tcggccctga ggagagtagt tatggctcac cttttactcc 1050

 ggctaagaga cctaagagga aagttgcccc taagaggaga caggaaagac 1100

 cagttgctcc tccaaagaaa agaagaagaa aaatacatag gatggatcat 1150

 tatgctgcgg aaactcgtca ggacaaaatg acaaatcctc tgagggaaat 1200

 cgacaaaatt gtggggcaat taatggatgg actgaaacaa ctaaaactgc 1250

 gtcggtgtgt caacgtcatc tttgtcggag accatggaat ggaagatgtc 1300

 acatgtgata gaactgagtt cttgagtaat tacctaacta atgtggatga 1350

 tattacttta gtgcctggaa ctctaggaag aattcgatcc aaatttagca 1400

 acaatgctaa atatgacccc aaagccatta ttgccaatct cacgtgtaaa 1450

 aaaccagatc agcactttaa gccttacttg aaacagcacc ttcccaaacg 1500

 tttgcactat gccaacaaca gaagaattga ggatatccat ttattggtgg 1550

 aacgcagatg gcatgttgca aggaaacctt tggatgttta taagaaacca 1600

 tcaggaaaat gctttttcca gggagaccac ggatttgata acaaggtcaa 1650

 cagcatgcag actgtttttg taggttatgg cccaacattt aagtacaaga 1700

 ctaaagtgcc tccatttgaa aacattgaac tttacaatgt tatgtgtgat 1750

 ctcctgggat tgaagccagc tcctaataat gggacccatg gaagtttgaa 1800

 tcatctcctg cgcactaata ccttcaggcc aaccatgcca gaggaagtta 1850

 ccagacccaa ttatccaggg attatgtacc ttcagtctga ttttgacctg 1900

 ggctgcactt gtgatgataa ggtagagcca aagaacaagt tggatgaact 1950

 caacaaacgg cttcatacaa aagggtctac agaagagaga cacctcctct 2000

 atgggcgacc tgcagtgctt tatcggacta gatatgatat cttatatcac 2050

 actgactttg aaagtggtta tagtgaaata ttcctaatgc tactctggac 2100

 atcatatact gtttccaaac aggctgaggt ttccagcgtt cctgaccatc 2150

 tgaccagttg cgtccggcct gatgtccgtg tttctccgag tttcagtcag 2200

 aactgtttgg cctacaaaaa tgataagcag atgtcctacg gattcctctt 2250

 tcctccttat ctgagctctt caccagaggc taaatatgat gcattccttg 2300

 taaccaatat ggttccaatg tatcctgctt tcaaacgggt ctggaattat 2350

 ttccaaaggg tattggtgaa gaaatatgct tcggaaagaa atggagttaa 2400

 cgtgataagt ggaccaatct tcgactatga ctatgatggc ttacatgaca 2450

 cagaagacaa aataaaacag tacgtggaag gcagttccat tcctgttcca 2500

 actcactact acagcatcat caccagctgt ctggatttca ctcagcctgc 2550

 cgacaagtgt gacggccctc tctctgtgtc ctccttcatc ctgcctcacc 2600

 ggcctgacaa cgaggagagc tgcaatagct cagaggacga atcaaaatgg 2650

 gtagaagaac tcatgaagat gcacacagct agggtgcgtg acattgaaca 2700

 tctcaccagc ctggacttct tccgaaagac cagccgcagc tacccagaaa 2750

 tcctgacact caagacatac ctgcatacat atgagagcga gatttaactt 2800

 tctgagcatc tgcagtacag tcttatcaac tggttgtata tttttatatt 2850

 gtttttgtat ttattaattt gaaaccagga cattaaaaat gttagtattt 2900

 taatcctgta ccaaatctga catattatgc ctgaatgact ccactgtttt 2950

 tctctaatgc ttgatttagg tagccttgtg ttctgagtag agcttgtaat 3000

 aaatactgca gcttgagaaa aagtggaagc ttctaaatgg tgctgcagat 3050

 ttgatatttg cattgaggaa atattaattt tccaatgcac agttgccaca 3100

 tttagtcctg tactgtatgg aaacactgat tttgtaaagt tgcctttatt 3150

 tgctgttaac tgttaactat gacagatata tttaagcctt ataaaccaat 3200

 cttaaacata ataaatcaca cattcagttt t 3231

<210> 2007
<211> 915
<212> PRT
<213> Homo sapien

<400> 2007
 Met Ala Arg Arg Ser Ser Phe Gln Ser Cys Gln Ile Ile Ser Leu
   1               5                  10                  15

 Phe Thr Phe Ala Val Gly Val Ser Ile Cys Leu Gly Phe Thr Ala
                  20                  25                  30

 His Arg Ile Lys Arg Ala Glu Gly Trp Glu Glu Gly Pro Pro Thr
                  35                  40                  45

 Val Leu Ser Asp Ser Pro Trp Thr Asn Ile Ser Gly Ser Cys Lys
                  50                  55                  60

 Gly Arg Cys Phe Glu Leu Gln Glu Ala Gly Pro Pro Asp Cys Arg
                  65                  70                  75

 Cys Asp Asn Leu Cys Lys Ser Tyr Thr Ser Cys Cys His Asp Phe
                  80                  85                  90

 Asp Glu Leu Cys Leu Lys Thr Ala Arg Gly Trp Glu Cys Thr Lys
                  95                 100                 105

 Asp Arg Cys Gly Glu Val Arg Asn Glu Glu Asn Ala Cys His Cys
                 110                 115                 120

 Ser Glu Asp Cys Leu Ala Arg Gly Asp Cys Cys Thr Asn Tyr Gln
                 125                 130                 135

 Val Val Cys Lys Gly Glu Ser His Trp Val Asp Asp Asp Cys Glu
                 140                 145                 150

 Glu Ile Lys Ala Ala Glu Cys Pro Ala Gly Phe Val Arg Pro Pro
                 155                 160                 165

 Leu Ile Ile Phe Ser Val Asp Gly Phe Arg Ala Ser Tyr Met Lys
                 170                 175                 180

 Lys Gly Ser Lys Val Met Pro Asn Ile Glu Lys Leu Arg Ser Cys
                 185                 190                 195

 Gly Thr His Ser Pro Tyr Met Arg Pro Val Tyr Pro Thr Lys Thr
                 200                 205                 210

 Phe Pro Asn Leu Tyr Thr Leu Ala Thr Gly Leu Tyr Pro Glu Ser
                 215                 220                 225

 His Gly Ile Val Gly Asn Ser Met Tyr Asp Pro Val Phe Asp Ala
                 230                 235                 240

 Thr Phe His Leu Arg Gly Arg Glu Lys Phe Asn His Arg Trp Trp
                 245                 250                 255

 Gly Gly Gln Pro Leu Trp Ile Thr Ala Thr Lys Gln Gly Val Lys
                 260                 265                 270

 Ala Gly Thr Phe Phe Trp Ser Val Val Ile Pro His Glu Arg Arg
                 275                 280                 285

 Ile Leu Thr Ile Leu Arg Trp Leu Thr Leu Pro Asp His Glu Arg
                 290                 295                 300

 Pro Ser Val Tyr Ala Phe Tyr Ser Glu Gln Pro Asp Phe Ser Gly
                 305                 310                 315

 His Lys Tyr Gly Pro Phe Gly Pro Glu Glu Ser Ser Tyr Gly Ser
                 320                 325                 330

 Pro Phe Thr Pro Ala Lys Arg Pro Lys Arg Lys Val Ala Pro Lys
                 335                 340                 345

 Arg Arg Gln Glu Arg Pro Val Ala Pro Pro Lys Lys Arg Arg Arg
                 350                 355                 360

 Lys Ile His Arg Met Asp His Tyr Ala Ala Glu Thr Arg Gln Asp
                 365                 370                 375

 Lys Met Thr Asn Pro Leu Arg Glu Ile Asp Lys Ile Val Gly Gln
                 380                 385                 390

 Leu Met Asp Gly Leu Lys Gln Leu Lys Leu Arg Arg Cys Val Asn
                 395                 400                 405

 Val Ile Phe Val Gly Asp His Gly Met Glu Asp Val Thr Cys Asp
                 410                 415                 420

 Arg Thr Glu Phe Leu Ser Asn Tyr Leu Thr Asn Val Asp Asp Ile
                 425                 430                 435

 Thr Leu Val Pro Gly Thr Leu Gly Arg Ile Arg Ser Lys Phe Ser
                 440                 445                 450

 Asn Asn Ala Lys Tyr Asp Pro Lys Ala Ile Ile Ala Asn Leu Thr
                 455                 460                 465

 Cys Lys Lys Pro Asp Gln His Phe Lys Pro Tyr Leu Lys Gln His
                 470                 475                 480

 Leu Pro Lys Arg Leu His Tyr Ala Asn Asn Arg Arg Ile Glu Asp
                 485                 490                 495

 Ile His Leu Leu Val Glu Arg Arg Trp His Val Ala Arg Lys Pro
                 500                 505                 510

 Leu Asp Val Tyr Lys Lys Pro Ser Gly Lys Cys Phe Phe Gln Gly
                 515                 520                 525

 Asp His Gly Phe Asp Asn Lys Val Asn Ser Met Gln Thr Val Phe
                 530                 535                 540

 Val Gly Tyr Gly Pro Thr Phe Lys Tyr Lys Thr Lys Val Pro Pro
                 545                 550                 555

 Phe Glu Asn Ile Glu Leu Tyr Asn Val Met Cys Asp Leu Leu Gly
                 560                 565                 570

 Leu Lys Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn His
                 575                 580                 585

 Leu Leu Arg Thr Asn Thr Phe Arg Pro Thr Met Pro Glu Glu Val
                 590                 595                 600

 Thr Arg Pro Asn Tyr Pro Gly Ile Met Tyr Leu Gln Ser Asp Phe
                 605                 610                 615

 Asp Leu Gly Cys Thr Cys Asp Asp Lys Val Glu Pro Lys Asn Lys
                 620                 625                 630

 Leu Asp Glu Leu Asn Lys Arg Leu His Thr Lys Gly Ser Thr Glu
                 635                 640                 645

 Glu Arg His Leu Leu Tyr Gly Arg Pro Ala Val Leu Tyr Arg Thr
                 650                 655                 660

 Arg Tyr Asp Ile Leu Tyr His Thr Asp Phe Glu Ser Gly Tyr Ser
                 665                 670                 675

 Glu Ile Phe Leu Met Leu Leu Trp Thr Ser Tyr Thr Val Ser Lys
                 680                 685                 690

 Gln Ala Glu Val Ser Ser Val Pro Asp His Leu Thr Ser Cys Val
                 695                 700                 705

 Arg Pro Asp Val Arg Val Ser Pro Ser Phe Ser Gln Asn Cys Leu
                 710                 715                 720

 Ala Tyr Lys Asn Asp Lys Gln Met Ser Tyr Gly Phe Leu Phe Pro
                 725                 730                 735

 Pro Tyr Leu Ser Ser Ser Pro Glu Ala Lys Tyr Asp Ala Phe Leu
                 740                 745                 750

 Val Thr Asn Met Val Pro Met Tyr Pro Ala Phe Lys Arg Val Trp
                 755                 760                 765

 Asn Tyr Phe Gln Arg Val Leu Val Lys Lys Tyr Ala Ser Glu Arg
                 770                 775                 780

 Asn Gly Val Asn Val Ile Ser Gly Pro Ile Phe Asp Tyr Asp Tyr
                 785                 790                 795

 Asp Gly Leu His Asp Thr Glu Asp Lys Ile Lys Gln Tyr Val Glu
                 800                 805                 810

 Gly Ser Ser Ile Pro Val Pro Thr His Tyr Tyr Ser Ile Ile Thr
                 815                 820                 825

 Ser Cys Leu Asp Phe Thr Gln Pro Ala Asp Lys Cys Asp Gly Pro
                 830                 835                 840

 Leu Ser Val Ser Ser Phe Ile Leu Pro His Arg Pro Asp Asn Glu
                 845                 850                 855

 Glu Ser Cys Asn Ser Ser Glu Asp Glu Ser Lys Trp Val Glu Glu
                 860                 865                 870

 Leu Met Lys Met His Thr Ala Arg Val Arg Asp Ile Glu His Leu
                 875                 880                 885

 Thr Ser Leu Asp Phe Phe Arg Lys Thr Ser Arg Ser Tyr Pro Glu
                 890                 895                 900

 Ile Leu Thr Leu Lys Thr Tyr Leu His Thr Tyr Glu Ser Glu Ile
                 905                 910                 915

<210> 2008
<211> 1556
<212> DNA
<213> Homo sapien

<400> 2008
 gcagccgcgg tgtcgcgaag tcctcccggg ttgcccccgc ggcgtcagag 50

 ggagggcggg cgccgcgttg gtgacggcga ccctgcagcc caaggagcgc 100

 tccactcgct gccgccggag ggccggtgac ctcttggcta ccccgcgtcg 150

 gaggcttaga tggctcaggc gaagatcaac gctaaagcca acgaggggcg 200

 cttctgccgc tcctcctcca tggctgaccg ctccagccgc ctgctggaga 250

 gcctggacca gctggagctc agggttgaag ctttgagaga agcagcaact 300

 gctgttgagc aagagaaaga aatccttctg gaaatgatcc acagtatcca 350

 aaatagccag gacatgaggc agatcagtga cggagaaaga gaagaattaa 400

 atctgactgc aaaccgtttg atgggaagaa ctctcaccgt tgaagtgtca 450

 gtagaaacaa ttagaaaccc ccagcagcaa gaatccctaa agcatgccac 500

 aaggattatt gatgaggtgg tcaataagtt tctggatgat ttgggaaatg 550

 ccaagagtca tttaatgtcg ctctacagtg catgttcatc tgaggtgcca 600

 catgggccag ttgatcagaa gtttcaatcc atagtaattg gctgtgctct 650

 tgaagatcag aagaaaatta agagaagatt agagactctg cttagaaata 700

 ttgaaaactc tgacaaggcc atcaagctat tagagcattc taaaggagct 750

 ggttccaaaa ctctgcaaca aaatgctgaa agcagattca attagtcttc 800

 aaacctaaga gcatttacac aatacacaag gtgtaaaaat gataaaatac 850

 tattttaatt gataactagt tctttgttag gtataaccac ttagttgaca 900

 ctgatagttg tttcagatga ggaaaatatt ccatcaagta tcttcagttt 950

 tgtgaataac aaaactagca atattttaat tatctatcta gagatttttt 1000

 agattgaatt cttgtcttgt actaggatct agcatatttc actattctgt 1050

 ggatgaatac atagtttgtg gggaaaacaa acgttcagct aggggcaaaa 1100

 agcatgactg ctttttcctg tctggcatgg aatcacgcag tcaccttggg 1150

 catttagttt actagaaatt ctttactgaa gcagcacaca catttactac 1200

 acacacagtg ttaacaaagc actgtgctta gagggtaaaa aggaatcaca 1250

 aaacaagaat ctttccaaag ttgtctcatt cagcaatgtt aaggcatctg 1300

 tatcaaatta ttttggatgt aaagattcct gtgtctcata atatgaatgt 1350

 attttttgat atacaagaaa ctgacataaa atgtgagaaa accacctata 1400

 atttaccact gtgaacaatt atatatctat ctgcttcatc ttttctcaaa 1450

 tgcatcaatt ctctaaaatt cctatattgt aacttgcctt tttttaaaaa 1500

 agttagatgc tgatataaag tctgcttaat tgtcaactta aaaaaaaaaa 1550

 aaaaaa 1556

<210> 2009
<211> 211
<212> PRT
<213> Homo sapien

<400> 2009
 Met Ala Gln Ala Lys Ile Asn Ala Lys Ala Asn Glu Gly Arg Phe
   1               5                  10                  15

 Cys Arg Ser Ser Ser Met Ala Asp Arg Ser Ser Arg Leu Leu Glu
                  20                  25                  30

 Ser Leu Asp Gln Leu Glu Leu Arg Val Glu Ala Leu Arg Glu Ala
                  35                  40                  45

 Ala Thr Ala Val Glu Gln Glu Lys Glu Ile Leu Leu Glu Met Ile
                  50                  55                  60

 His Ser Ile Gln Asn Ser Gln Asp Met Arg Gln Ile Ser Asp Gly
                  65                  70                  75

 Glu Arg Glu Glu Leu Asn Leu Thr Ala Asn Arg Leu Met Gly Arg
                  80                  85                  90

 Thr Leu Thr Val Glu Val Ser Val Glu Thr Ile Arg Asn Pro Gln
                  95                 100                 105

 Gln Gln Glu Ser Leu Lys His Ala Thr Arg Ile Ile Asp Glu Val
                 110                 115                 120

 Val Asn Lys Phe Leu Asp Asp Leu Gly Asn Ala Lys Ser His Leu
                 125                 130                 135

 Met Ser Leu Tyr Ser Ala Cys Ser Ser Glu Val Pro His Gly Pro
                 140                 145                 150

 Val Asp Gln Lys Phe Gln Ser Ile Val Ile Gly Cys Ala Leu Glu
                 155                 160                 165

 Asp Gln Lys Lys Ile Lys Arg Arg Leu Glu Thr Leu Leu Arg Asn
                 170                 175                 180

 Ile Glu Asn Ser Asp Lys Ala Ile Lys Leu Leu Glu His Ser Lys
                 185                 190                 195

 Gly Ala Gly Ser Lys Thr Leu Gln Gln Asn Ala Glu Ser Arg Phe
                 200                 205                 210

 Asn


<210> 2010
<211> 2825
<212> DNA
<213> Homo sapien

<400> 2010
 gcgaaattga ggtttcttgg tattgcgcgt ttctcttcct tgctgactct 50

 ccgaatggcc atggactcgt cgcttcaggc ccgcctgttt cccggtctcg 100

 ctatcaagat ccaacgcagt aatggtttaa ttcacagtgc caatgtaagg 150

 actgtgaact tggagaaatc ctgtgtttca gtggaatggg cagaaggagg 200

 tgccacaaag ggcaaagaga ttgattttga tgatgtggct gcaataaacc 250

 cagaactctt acagcttctt cccttacatc cgaaggacaa tctgcccttg 300

 caggaaaatg taacaatcca gaaacaaaaa cggagatccg tcaactccaa 350

 aattcctgct ccaaaagaaa gtcttcgaag ccgctccact cgcatgtcca 400

 ctgtctcaga gcttcgcatc acggctcagg agaatgacat ggaggtggag 450

 ctgcctgcag ctgcaaactc ccgcaagcag ttttcagttc ctcctgcccc 500

 cactaggcct tcctgccctg cagtggctga aataccattg aggatggtca 550

 gcgaggagat ggaagagcaa gtccattcca tccgtggcag ctcttctgca 600

 aaccctgtga actcagttcg gaggaaatca tgtcttgtga aggaagtgga 650

 aaaaatgaag aacaagcgag aagagaagaa ggcccagaac tctgaaatga 700

 gaatgaagag agctcaggag tatgacagta gttttccaaa ctgggaattt 750

 gcccgaatga ttaaagaatt tcgggctact ttggaatgtc atccacttac 800

 tatgactgat cctatcgaag agcacagaat atgtgtctgt gttaggaaac 850

 gcccactgaa taagcaagaa ttggccaaga aagaaattga tgtgatttcc 900

 attcctagca agtgtctcct cttggtacat gaacccaagt tgaaagtgga 950

 cttaacaaag tatctggaga accaagcatt ctgctttgac tttgcatttg 1000

 atgaaacagc ttcgaatgaa gttgtctaca ggttcacagc aaggccactg 1050

 gtacagacaa tctttgaagg tggaaaagca acttgttttg catatggcca 1100

 gacaggaagt ggcaagacac atactatggg cggagacctc tctgggaaag 1150

 cccagaatgc atccaaaggg atctatgcca tggcctcccg ggacgtcttc 1200

 ctcctgaaga atcaaccctg ctaccggaag ttgggcctgg aagtctatgt 1250

 gacattcttc gagatctaca atgggaagct gtttgacctg ctcaacaaga 1300

 aggccaagct gcgcgtgctg gaggacggca agcaacaggt gcaagtggtg 1350

 gggctgcagg agcatctggt taactctgct gatgatgtca tcaagatgct 1400

 cgacatgggc agcgcctgca gaacctctgg gcagacattt gccaactcca 1450

 attcctcccg ctcccacgcg tgcttccaaa ttattcttcg agctaaaggg 1500

 agaatgcatg gcaagttctc tttggtagat ctggcaggga atgagcgagg 1550

 cgcagacact tccagtgctg accggcagac ccgcatggag ggcgcagaaa 1600

 tcaacaagag tctcttagcc ctgaaggagt gcatcagggc cctgggacag 1650

 aacaaggctc acaccccgtt ccgtgagagc aagctgacac aggtgctgag 1700

 ggactccttc attggggaga actctaggac ttgcatgatt gccacgatct 1750

 caccaggcat aagctcctgt gaatatactt taaacaccct gagatatgca 1800

 gacagggtca aggagctgag cccccacagt gggcccagtg gagagcagtt 1850

 gattcaaatg gaaacagaag agatggaagc ctgctctaac ggggcgctga 1900

 ttccaggcaa tttatccaag gaagaggagg aactgtcttc ccagatgtcc 1950

 agctttaacg aagccatgac tcagatcagg gagctggagg agaaggctat 2000

 ggaagagctc aaggagatca tacagcaagg accagactgg cttgagctct 2050

 ctgagatgac cgagcagcca gactatgacc tggagacctt tgtgaacaaa 2100

 gcggaatctg ctctggccca gcaagccaag catttctcag ccctgcgaga 2150

 tgtcatcaag gccttacgcc tggccatgca gctggaagag caggctagca 2200

 gacaaataag cagcaagaaa cggccccagt gacgactgca aataaaaatc 2250

 tgtttggttt gacacccagc ctcttccctg gccctcccca gagaactttg 2300

 ggtacctggt gggtctaggc agggtctgag ctgggacagg ttctggtaaa 2350

 tgccaagtat gggggcatct gggcccaggg cagctgggga gggggtcaga 2400

 gtgacatggg acactccttt tctgttcctc agttgtcgcc ctcacgagag 2450

 gaaggagctc ttagttaccc ttttgtgttg cccttctttc catcaagggg 2500

 aatgttctca gcatagagct ttctccgcag catcctgcct gcgtggactg 2550

 gctgctaatg gagagctccc tggggttgtc ctggctctgg ggagagagac 2600

 ggagccttta gtacagctat ctgctggctc taaaccttct acgcctttgg 2650

 gccgagcact gaatgtcttg tactttaaaa aaatgtttct gagacctctt 2700

 tctactttac tgtctcccta gagtcctaga ggatccctac tgttttctgt 2750

 tttatgtgtt tatacattgt atgtaacaat aaagagaaaa aataaaaaaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaaa 2825

<210> 2011
<211> 725
<212> PRT
<213> Homo sapien

<400> 2011
 Met Ala Met Asp Ser Ser Leu Gln Ala Arg Leu Phe Pro Gly Leu
   1               5                  10                  15

 Ala Ile Lys Ile Gln Arg Ser Asn Gly Leu Ile His Ser Ala Asn
                  20                  25                  30

 Val Arg Thr Val Asn Leu Glu Lys Ser Cys Val Ser Val Glu Trp
                  35                  40                  45

 Ala Glu Gly Gly Ala Thr Lys Gly Lys Glu Ile Asp Phe Asp Asp
                  50                  55                  60

 Val Ala Ala Ile Asn Pro Glu Leu Leu Gln Leu Leu Pro Leu His
                  65                  70                  75

 Pro Lys Asp Asn Leu Pro Leu Gln Glu Asn Val Thr Ile Gln Lys
                  80                  85                  90

 Gln Lys Arg Arg Ser Val Asn Ser Lys Ile Pro Ala Pro Lys Glu
                  95                 100                 105

 Ser Leu Arg Ser Arg Ser Thr Arg Met Ser Thr Val Ser Glu Leu
                 110                 115                 120

 Arg Ile Thr Ala Gln Glu Asn Asp Met Glu Val Glu Leu Pro Ala
                 125                 130                 135

 Ala Ala Asn Ser Arg Lys Gln Phe Ser Val Pro Pro Ala Pro Thr
                 140                 145                 150

 Arg Pro Ser Cys Pro Ala Val Ala Glu Ile Pro Leu Arg Met Val
                 155                 160                 165

 Ser Glu Glu Met Glu Glu Gln Val His Ser Ile Arg Gly Ser Ser
                 170                 175                 180

 Ser Ala Asn Pro Val Asn Ser Val Arg Arg Lys Ser Cys Leu Val
                 185                 190                 195

 Lys Glu Val Glu Lys Met Lys Asn Lys Arg Glu Glu Lys Lys Ala
                 200                 205                 210

 Gln Asn Ser Glu Met Arg Met Lys Arg Ala Gln Glu Tyr Asp Ser
                 215                 220                 225

 Ser Phe Pro Asn Trp Glu Phe Ala Arg Met Ile Lys Glu Phe Arg
                 230                 235                 240

 Ala Thr Leu Glu Cys His Pro Leu Thr Met Thr Asp Pro Ile Glu
                 245                 250                 255

 Glu His Arg Ile Cys Val Cys Val Arg Lys Arg Pro Leu Asn Lys
                 260                 265                 270

 Gln Glu Leu Ala Lys Lys Glu Ile Asp Val Ile Ser Ile Pro Ser
                 275                 280                 285

 Lys Cys Leu Leu Leu Val His Glu Pro Lys Leu Lys Val Asp Leu
                 290                 295                 300

 Thr Lys Tyr Leu Glu Asn Gln Ala Phe Cys Phe Asp Phe Ala Phe
                 305                 310                 315

 Asp Glu Thr Ala Ser Asn Glu Val Val Tyr Arg Phe Thr Ala Arg
                 320                 325                 330

 Pro Leu Val Gln Thr Ile Phe Glu Gly Gly Lys Ala Thr Cys Phe
                 335                 340                 345

 Ala Tyr Gly Gln Thr Gly Ser Gly Lys Thr His Thr Met Gly Gly
                 350                 355                 360

 Asp Leu Ser Gly Lys Ala Gln Asn Ala Ser Lys Gly Ile Tyr Ala
                 365                 370                 375

 Met Ala Ser Arg Asp Val Phe Leu Leu Lys Asn Gln Pro Cys Tyr
                 380                 385                 390

 Arg Lys Leu Gly Leu Glu Val Tyr Val Thr Phe Phe Glu Ile Tyr
                 395                 400                 405

 Asn Gly Lys Leu Phe Asp Leu Leu Asn Lys Lys Ala Lys Leu Arg
                 410                 415                 420

 Val Leu Glu Asp Gly Lys Gln Gln Val Gln Val Val Gly Leu Gln
                 425                 430                 435

 Glu His Leu Val Asn Ser Ala Asp Asp Val Ile Lys Met Leu Asp
                 440                 445                 450

 Met Gly Ser Ala Cys Arg Thr Ser Gly Gln Thr Phe Ala Asn Ser
                 455                 460                 465

 Asn Ser Ser Arg Ser His Ala Cys Phe Gln Ile Ile Leu Arg Ala
                 470                 475                 480

 Lys Gly Arg Met His Gly Lys Phe Ser Leu Val Asp Leu Ala Gly
                 485                 490                 495

 Asn Glu Arg Gly Ala Asp Thr Ser Ser Ala Asp Arg Gln Thr Arg
                 500                 505                 510

 Met Glu Gly Ala Glu Ile Asn Lys Ser Leu Leu Ala Leu Lys Glu
                 515                 520                 525

 Cys Ile Arg Ala Leu Gly Gln Asn Lys Ala His Thr Pro Phe Arg
                 530                 535                 540

 Glu Ser Lys Leu Thr Gln Val Leu Arg Asp Ser Phe Ile Gly Glu
                 545                 550                 555

 Asn Ser Arg Thr Cys Met Ile Ala Thr Ile Ser Pro Gly Ile Ser
                 560                 565                 570

 Ser Cys Glu Tyr Thr Leu Asn Thr Leu Arg Tyr Ala Asp Arg Val
                 575                 580                 585

 Lys Glu Leu Ser Pro His Ser Gly Pro Ser Gly Glu Gln Leu Ile
                 590                 595                 600

 Gln Met Glu Thr Glu Glu Met Glu Ala Cys Ser Asn Gly Ala Leu
                 605                 610                 615

 Ile Pro Gly Asn Leu Ser Lys Glu Glu Glu Glu Leu Ser Ser Gln
                 620                 625                 630

 Met Ser Ser Phe Asn Glu Ala Met Thr Gln Ile Arg Glu Leu Glu
                 635                 640                 645

 Glu Lys Ala Met Glu Glu Leu Lys Glu Ile Ile Gln Gln Gly Pro
                 650                 655                 660

 Asp Trp Leu Glu Leu Ser Glu Met Thr Glu Gln Pro Asp Tyr Asp
                 665                 670                 675

 Leu Glu Thr Phe Val Asn Lys Ala Glu Ser Ala Leu Ala Gln Gln
                 680                 685                 690

 Ala Lys His Phe Ser Ala Leu Arg Asp Val Ile Lys Ala Leu Arg
                 695                 700                 705

 Leu Ala Met Gln Leu Glu Glu Gln Ala Ser Arg Gln Ile Ser Ser
                 710                 715                 720

 Lys Lys Arg Pro Gln
                 725

<210> 2012
<211> 3801
<212> DNA
<213> Homo sapien

<400> 2012
 aaggtaaagc cactagagag aaactgaaag aaaacattct taagataaat 50

 tgaattgaca ttttctctct aaaatatgat ttatagacca cagataggaa 100

 ttaagagttt cctgataatt ttggcttcat attattttaa aggattatca 150

 agaggaaatt gctattgctc aagagaacaa aatacagctc caacaaatgg 200

 gagaacgact tgctaaagcc agccatgaaa gcaaagcatc tgagattgaa 250

 tacaagctgg gaaaggtcaa cgaccggtgg cagcatctcc tggacctcat 300

 tgcagccagg gtgaagaagc tgaaggagac cctggtagcc gtgcagcagc 350

 ttgataagaa catgagcagc ctgaggacct ggctcgctca catcgagtca 400

 gagctggcca agccaatagt ctacgattcc tgtaactcgg aagaaataca 450

 gagaaagctt aatgagcagc aggagcttca gagagacata gagaagcaca 500

 gtacaggtgt tgcatctgtc ctcaacctgt gtgaagtcct gctgcacgac 550

 tgtgacgcct gtgccactga tgccgagtgt gactctatac agcaggctac 600

 gagaaacctg gaccggcggt ggagaaacat ttgtgctatg tccatggaaa 650

 ggaggctgaa aatcgaagag acgtggcgat tgtggcagaa atttctggat 700

 gactattcac gttttgaaga ttggctgaag tcttcagaaa ggacagctgc 750

 ttttcccagc tcttctgggg tgatctatac agttgccaag gaagaactaa 800

 agaaatttga ggctttccag cgacaggtcc acgagtgcct gacgcagctg 850

 gaactgatca acaagcagta ccgccgcctg gccagggaga accgcactga 900

 ttcagcatgt agcctcaaac agatggttca cgaaggcaac cagagatggg 950

 acaacctgca aaagcgtgtc acctccatct tgcgcagact caagcatttt 1000

 attggccagc gtgaggagtt tgagactgcg cgggacagca ttctggtctg 1050

 gctcacagag atggatctgc agctcactaa tattgaacat ttttctgagt 1100

 gtgatgttca agctaaaata aagcaactca aggccttcca gcaggaaatt 1150

 tcactgaacc acaataagat tgagcagata attgcccaag gagaacagct 1200

 gatagaaaag agtgagccct tggatgcagc gatcatcgag gaggaactag 1250

 atgagctccg acggtactgc caggaggtct tcgggcgtgt ggaaagatac 1300

 cataagaaac tgatccgcct gcctctccca gacgatgagc acgacctctc 1350

 agacagggag ctggagctgg aagactctgc agctctgtcg gacctgcact 1400

 ggcacgaccg ctctgcagac agcctgcttt ctccacagcc ttcctccaat 1450

 ctctccctct cgctcgctca gcccctccgg agcgagcggt caggacgaga 1500

 caccccagct agtgtggact ccatccccct ggagtgggat cacgactatg 1550

 acctcagtcg ggacctggag tctgcaatgt ccagagctct gccctctgag 1600

 gatgaagaag gtcaggatga caaagatttc tacctccggg gagctgttgc 1650

 cttatcagat gtaatgatcc ccgaaagccc tgaggcctat gtaaaactca 1700

 cagaaaatgc aatcaaaaat acctccgggg accacagtgc cctagagtca 1750

 cagatccgac aactgggcaa agccctggat gatagccgct ttcagataca 1800

 gcaaaccgaa aatatcattc gcagcaaaac tcccacgggg ccggagctag 1850

 acaccagcta caaaggctac atgaaactgc tgggcgaatg cagtagcagt 1900

 atagactccg tgaagagact ggagcacaaa ctgaaggagg aagaggagag 1950

 ccttcctggc tttgttaacc tgcatagtac cgaaacccaa acggctggtg 2000

 tgattgaccg atgggagctt ctccaggccc aggcattgag caaggagttg 2050

 aggatgaagc agaacctcca gaagtggcag cagtttaact cagacttgaa 2100

 cagcatctgg gcctggctgg gggacacgga ggaggagttg gaacagctcc 2150

 agcgtctgga actcagcact gacatccaga ccatcgagct ccagatcaaa 2200

 aagctcaagg agctccagaa agctgtggac caccgcaaag ccatcatcct 2250

 ctccatcaat ctctgcagcc ctgagttcac ccaggctgac agcaaggaga 2300

 gccgggacct gcaggatcgc ttgtcgcaga tgaatgggcg ctgggaccga 2350

 gtgtgctctc tgctggagga gtggcggggc ctgctgcagg atgccctgat 2400

 gcagtgccag ggtttccatg aaatgagcca tggtttgctt cttatgctgg 2450

 agaacattga cagaaggaaa aatgaaattg tccctattga ttctaacctt 2500

 gatgcagaga tacttcagga ccatcacaaa cagcttatgc aaataaagca 2550

 tgagctgttg gaatcccaac tcagagtagc ctctttgcaa gacatgtctt 2600

 gccaactact ggtgaatgct gaaggaacag actgtttaga agccaaagaa 2650

 aaagtccatg ttattggaaa tcggctcaaa cttctcttga aggaggtcag 2700

 tcgtcatatc aaggaactgg agaagttatt agacgtgtca agtagtcagc 2750

 aggatttgtc ttcctggtct tctgctgatg aactggacac ctcagggtct 2800

 gtgagtccca catcaggaag gagcacccca aacagacaga aaacgccacg 2850

 aggcaagtgt agtctctcac agcctggacc ctctgtcagc agtccacata 2900

 gcaggtccac aaaaggtggc tccgattcct ccctttctga gccagggcca 2950

 ggtcggtccg gccgcggctt cctgttcaga gtcctccgag cagctcttcc 3000

 ccttcagctt ctcctgctcc tcctcatcgg gcttgcctgc cttgtaccaa 3050

 tgtcagagga agactacagc tgtgccctct ccaacaactt tgcccggtca 3100

 ttccacccca tgctcagata cacgaatggc cctcctccac tctgaactaa 3150

 gcagatgcca tctgcagaag tgctggtagc ataaggagga tcgggtcata 3200

 agcaatccca aactaccaac aagaggacct tgatcttggc gaaagccctc 3250

 ggtgtggcag ctttagccct cctccagatc acatgtgtgc aaattatggc 3300

 ttcagaggtg gaagataaac agtgacgggg gaacaaacag acaacaagaa 3350

 ggtttggaag aaatctggtt tgagactctg aaccttagca ctaaggagat 3400

 tgagtaagga cctccaaagt tccccggact catgaattct gggcccttgg 3450

 cccattctgt gcacagccaa ggacttcagt agaccatctg ggcagctttc 3500

 ccatggtgct gctccaacca tcagataaat gaccctccca agcaccatgt 3550

 cagtgtcgta caatctacca accaaccagt gctgaagaga ttttagaacc 3600

 ttgtaacata caatttttaa gagcttatat ggcagcttcc tttttacctt 3650

 gttttccttt ggggcatgat gttttaacct ttgctttaga agcacaagct 3700

 gtaaatctaa aaggcacttt tttttagagg tataaagaaa aactagatgt 3750

 aataaataag atcatggaag gctttatgtg aaaaaagttg aatgttatag 3800

 t 3801

<210> 2013
<211> 982
<212> PRT
<213> Homo sapien

<400> 2013
 Met Gly Glu Arg Leu Ala Lys Ala Ser His Glu Ser Lys Ala Ser
   1               5                  10                  15

 Glu Ile Glu Tyr Lys Leu Gly Lys Val Asn Asp Arg Trp Gln His
                  20                  25                  30

 Leu Leu Asp Leu Ile Ala Ala Arg Val Lys Lys Leu Lys Glu Thr
                  35                  40                  45

 Leu Val Ala Val Gln Gln Leu Asp Lys Asn Met Ser Ser Leu Arg
                  50                  55                  60

 Thr Trp Leu Ala His Ile Glu Ser Glu Leu Ala Lys Pro Ile Val
                  65                  70                  75

 Tyr Asp Ser Cys Asn Ser Glu Glu Ile Gln Arg Lys Leu Asn Glu
                  80                  85                  90

 Gln Gln Glu Leu Gln Arg Asp Ile Glu Lys His Ser Thr Gly Val
                  95                 100                 105

 Ala Ser Val Leu Asn Leu Cys Glu Val Leu Leu His Asp Cys Asp
                 110                 115                 120

 Ala Cys Ala Thr Asp Ala Glu Cys Asp Ser Ile Gln Gln Ala Thr
                 125                 130                 135

 Arg Asn Leu Asp Arg Arg Trp Arg Asn Ile Cys Ala Met Ser Met
                 140                 145                 150

 Glu Arg Arg Leu Lys Ile Glu Glu Thr Trp Arg Leu Trp Gln Lys
                 155                 160                 165

 Phe Leu Asp Asp Tyr Ser Arg Phe Glu Asp Trp Leu Lys Ser Ser
                 170                 175                 180

 Glu Arg Thr Ala Ala Phe Pro Ser Ser Ser Gly Val Ile Tyr Thr
                 185                 190                 195

 Val Ala Lys Glu Glu Leu Lys Lys Phe Glu Ala Phe Gln Arg Gln
                 200                 205                 210

 Val His Glu Cys Leu Thr Gln Leu Glu Leu Ile Asn Lys Gln Tyr
                 215                 220                 225

 Arg Arg Leu Ala Arg Glu Asn Arg Thr Asp Ser Ala Cys Ser Leu
                 230                 235                 240

 Lys Gln Met Val His Glu Gly Asn Gln Arg Trp Asp Asn Leu Gln
                 245                 250                 255

 Lys Arg Val Thr Ser Ile Leu Arg Arg Leu Lys His Phe Ile Gly
                 260                 265                 270

 Gln Arg Glu Glu Phe Glu Thr Ala Arg Asp Ser Ile Leu Val Trp
                 275                 280                 285

 Leu Thr Glu Met Asp Leu Gln Leu Thr Asn Ile Glu His Phe Ser
                 290                 295                 300

 Glu Cys Asp Val Gln Ala Lys Ile Lys Gln Leu Lys Ala Phe Gln
                 305                 310                 315

 Gln Glu Ile Ser Leu Asn His Asn Lys Ile Glu Gln Ile Ile Ala
                 320                 325                 330

 Gln Gly Glu Gln Leu Ile Glu Lys Ser Glu Pro Leu Asp Ala Ala
                 335                 340                 345

 Ile Ile Glu Glu Glu Leu Asp Glu Leu Arg Arg Tyr Cys Gln Glu
                 350                 355                 360

 Val Phe Gly Arg Val Glu Arg Tyr His Lys Lys Leu Ile Arg Leu
                 365                 370                 375

 Pro Leu Pro Asp Asp Glu His Asp Leu Ser Asp Arg Glu Leu Glu
                 380                 385                 390

 Leu Glu Asp Ser Ala Ala Leu Ser Asp Leu His Trp His Asp Arg
                 395                 400                 405

 Ser Ala Asp Ser Leu Leu Ser Pro Gln Pro Ser Ser Asn Leu Ser
                 410                 415                 420

 Leu Ser Leu Ala Gln Pro Leu Arg Ser Glu Arg Ser Gly Arg Asp
                 425                 430                 435

 Thr Pro Ala Ser Val Asp Ser Ile Pro Leu Glu Trp Asp His Asp
                 440                 445                 450

 Tyr Asp Leu Ser Arg Asp Leu Glu Ser Ala Met Ser Arg Ala Leu
                 455                 460                 465

 Pro Ser Glu Asp Glu Glu Gly Gln Asp Asp Lys Asp Phe Tyr Leu
                 470                 475                 480

 Arg Gly Ala Val Ala Leu Ser Asp Val Met Ile Pro Glu Ser Pro
                 485                 490                 495

 Glu Ala Tyr Val Lys Leu Thr Glu Asn Ala Ile Lys Asn Thr Ser
                 500                 505                 510

 Gly Asp His Ser Ala Leu Glu Ser Gln Ile Arg Gln Leu Gly Lys
                 515                 520                 525

 Ala Leu Asp Asp Ser Arg Phe Gln Ile Gln Gln Thr Glu Asn Ile
                 530                 535                 540

 Ile Arg Ser Lys Thr Pro Thr Gly Pro Glu Leu Asp Thr Ser Tyr
                 545                 550                 555

 Lys Gly Tyr Met Lys Leu Leu Gly Glu Cys Ser Ser Ser Ile Asp
                 560                 565                 570

 Ser Val Lys Arg Leu Glu His Lys Leu Lys Glu Glu Glu Glu Ser
                 575                 580                 585

 Leu Pro Gly Phe Val Asn Leu His Ser Thr Glu Thr Gln Thr Ala
                 590                 595                 600

 Gly Val Ile Asp Arg Trp Glu Leu Leu Gln Ala Gln Ala Leu Ser
                 605                 610                 615

 Lys Glu Leu Arg Met Lys Gln Asn Leu Gln Lys Trp Gln Gln Phe
                 620                 625                 630

 Asn Ser Asp Leu Asn Ser Ile Trp Ala Trp Leu Gly Asp Thr Glu
                 635                 640                 645

 Glu Glu Leu Glu Gln Leu Gln Arg Leu Glu Leu Ser Thr Asp Ile
                 650                 655                 660

 Gln Thr Ile Glu Leu Gln Ile Lys Lys Leu Lys Glu Leu Gln Lys
                 665                 670                 675

 Ala Val Asp His Arg Lys Ala Ile Ile Leu Ser Ile Asn Leu Cys
                 680                 685                 690

 Ser Pro Glu Phe Thr Gln Ala Asp Ser Lys Glu Ser Arg Asp Leu
                 695                 700                 705

 Gln Asp Arg Leu Ser Gln Met Asn Gly Arg Trp Asp Arg Val Cys
                 710                 715                 720

 Ser Leu Leu Glu Glu Trp Arg Gly Leu Leu Gln Asp Ala Leu Met
                 725                 730                 735

 Gln Cys Gln Gly Phe His Glu Met Ser His Gly Leu Leu Leu Met
                 740                 745                 750

 Leu Glu Asn Ile Asp Arg Arg Lys Asn Glu Ile Val Pro Ile Asp
                 755                 760                 765

 Ser Asn Leu Asp Ala Glu Ile Leu Gln Asp His His Lys Gln Leu
                 770                 775                 780

 Met Gln Ile Lys His Glu Leu Leu Glu Ser Gln Leu Arg Val Ala
                 785                 790                 795

 Ser Leu Gln Asp Met Ser Cys Gln Leu Leu Val Asn Ala Glu Gly
                 800                 805                 810

 Thr Asp Cys Leu Glu Ala Lys Glu Lys Val His Val Ile Gly Asn
                 815                 820                 825

 Arg Leu Lys Leu Leu Leu Lys Glu Val Ser Arg His Ile Lys Glu
                 830                 835                 840

 Leu Glu Lys Leu Leu Asp Val Ser Ser Ser Gln Gln Asp Leu Ser
                 845                 850                 855

 Ser Trp Ser Ser Ala Asp Glu Leu Asp Thr Ser Gly Ser Val Ser
                 860                 865                 870

 Pro Thr Ser Gly Arg Ser Thr Pro Asn Arg Gln Lys Thr Pro Arg
                 875                 880                 885

 Gly Lys Cys Ser Leu Ser Gln Pro Gly Pro Ser Val Ser Ser Pro
                 890                 895                 900

 His Ser Arg Ser Thr Lys Gly Gly Ser Asp Ser Ser Leu Ser Glu
                 905                 910                 915

 Pro Gly Pro Gly Arg Ser Gly Arg Gly Phe Leu Phe Arg Val Leu
                 920                 925                 930

 Arg Ala Ala Leu Pro Leu Gln Leu Leu Leu Leu Leu Leu Ile Gly
                 935                 940                 945

 Leu Ala Cys Leu Val Pro Met Ser Glu Glu Asp Tyr Ser Cys Ala
                 950                 955                 960

 Leu Ser Asn Asn Phe Ala Arg Ser Phe His Pro Met Leu Arg Tyr
                 965                 970                 975

 Thr Asn Gly Pro Pro Pro Leu
                 980

<210> 2014
<211> 2089
<212> DNA
<213> Homo sapien

<400> 2014
 gtttgagcag cattgttaga gcctgtggaa aacactttac aactgtgtaa 50

 ctgtcttcat ctttacagag gaatagtcta caaaggaaga cttgtaacct 100

 ggagaagaga cctgtcattt actccatcct ttatagtgat gctacaggac 150

 gaagaggaat ggataaaaac attggcgagc aactcaataa agcgtatgaa 200

 gccttccggc aggcatgcat ggatagagat tctgcagtaa aagaattaca 250

 gcaaaagact gagaactatg agcagagaat acgtgaacaa caggaacagc 300

 tgtcacttca acagactatt attgacaagc taaaatctca gttacttctt 350

 gtgaattcca ctcaagataa caattatggc tgtgttcctc tgcttgaaga 400

 cagtgaaaca agaaagaata atttgactct tgatcagcca caagataaag 450

 tgatttcagg aatagcaaga gaaaaactac caaaggtaag aagacaagag 500

 gtttcttctc ctagaaaaga aacttcagca aggagtcttg gcagtccttt 550

 gctccatgaa aggggtaata tagagaagac tttctgggat ctgaaagaag 600

 aatttcataa aatatgcatg ctagcaaaag cacagaaaga ccacttaagc 650

 aaacttaata taccagacac tgcaactgaa acacagtgct ctgtgcctat 700

 acagtgtacg gataaaacag ataaacaaga agcgctgttt aagcctcagg 750

 ctaaagatga tataaataga ggtgcaccat ccatcacatc tgtcacacca 800

 agaggactgt gcagagatga ggaagacacc tcttttgaat cactttctaa 850

 attcaatgtc aagtttccac ctatggacaa tgactcaact ttcttacata 900

 gcactccaga gagacccggc atccttagtc ctgccacgtc tgaggcagtg 950

 tgccaagaga aatttaatat ggagttcaga gacaacccag ggaactttgt 1000

 taaaacagaa gaaactttat ttgaaattca gggaattgac cccatagctt 1050

 cagctataca aaaccttaaa acaactgaca aaacaaagcc ctcaaatctc 1100

 gtaaacactt gtatcaggac aactctggat agagctgcgt gtttgccacc 1150

 tggagaccat aatgcattat atgtaaatag cttcccactt ctggacccat 1200

 ctgatgcacc ttttccctca ctcgattccc cgggaaaagc aatccgagga 1250

 ccacagcagc ccatttggaa gccctttcct aatcaagaca gtgactcggt 1300

 ggtactaagt ggcacagact cagaactgca tatacctcga gtatgtgaat 1350

 tctgtcaagc agttttccca ccatccatta catccagggg ggatttcctt 1400

 cggcatctta attcacactt caatggagag acttaagaca catttgaaaa 1450

 cagacatatc aagttctatg tgatgatttt gggtttttaa tactataaat 1500

 acttgattgt aaactaaatt caagatcatt tataggaaaa tctagtttca 1550

 cagctatttg aatttttttc tggatttact atataactct tattttttaa 1600

 aagatcattc tgttctttca aggagaaata agcctaaaag aagaaaaaca 1650

 aaaaaaattc tgtataaaac tgtaatcctt tgtattcatg tttacagtgc 1700

 tattactata attcaaaatt atgtatgtga cttagagtta tataatcata 1750

 atttatgttt atttcaaata tctaagttta ttgcttggat ttctagtgag 1800

 agctgttgaa tttggtgatg tcaaatgttt ctagggtttt tttagtttgt 1850

 ttttattgaa aaatttaatt atttatgcta taggtgatat tctctttgaa 1900

 taaacctata atagaaaata gcagacaaca taaacatctt tgtaaatatc 1950

 aaacctaata catttcttgt ccagtgataa aacaactggt agaattattt 2000

 aaacacttta gatttttaaa taatatacat ggctttaatt tttactgtgt 2050

 gtatagctac atgatgaaat taattaaata ttaagaggt 2089

<210> 2015
<211> 425
<212> PRT
<213> Homo sapien

<400> 2015
 Met Asp Lys Asn Ile Gly Glu Gln Leu Asn Lys Ala Tyr Glu Ala
   1               5                  10                  15

 Phe Arg Gln Ala Cys Met Asp Arg Asp Ser Ala Val Lys Glu Leu
                  20                  25                  30

 Gln Gln Lys Thr Glu Asn Tyr Glu Gln Arg Ile Arg Glu Gln Gln
                  35                  40                  45

 Glu Gln Leu Ser Leu Gln Gln Thr Ile Ile Asp Lys Leu Lys Ser
                  50                  55                  60

 Gln Leu Leu Leu Val Asn Ser Thr Gln Asp Asn Asn Tyr Gly Cys
                  65                  70                  75

 Val Pro Leu Leu Glu Asp Ser Glu Thr Arg Lys Asn Asn Leu Thr
                  80                  85                  90

 Leu Asp Gln Pro Gln Asp Lys Val Ile Ser Gly Ile Ala Arg Glu
                  95                 100                 105

 Lys Leu Pro Lys Val Arg Arg Gln Glu Val Ser Ser Pro Arg Lys
                 110                 115                 120

 Glu Thr Ser Ala Arg Ser Leu Gly Ser Pro Leu Leu His Glu Arg
                 125                 130                 135

 Gly Asn Ile Glu Lys Thr Phe Trp Asp Leu Lys Glu Glu Phe His
                 140                 145                 150

 Lys Ile Cys Met Leu Ala Lys Ala Gln Lys Asp His Leu Ser Lys
                 155                 160                 165

 Leu Asn Ile Pro Asp Thr Ala Thr Glu Thr Gln Cys Ser Val Pro
                 170                 175                 180

 Ile Gln Cys Thr Asp Lys Thr Asp Lys Gln Glu Ala Leu Phe Lys
                 185                 190                 195

 Pro Gln Ala Lys Asp Asp Ile Asn Arg Gly Ala Pro Ser Ile Thr
                 200                 205                 210

 Ser Val Thr Pro Arg Gly Leu Cys Arg Asp Glu Glu Asp Thr Ser
                 215                 220                 225

 Phe Glu Ser Leu Ser Lys Phe Asn Val Lys Phe Pro Pro Met Asp
                 230                 235                 240

 Asn Asp Ser Thr Phe Leu His Ser Thr Pro Glu Arg Pro Gly Ile
                 245                 250                 255

 Leu Ser Pro Ala Thr Ser Glu Ala Val Cys Gln Glu Lys Phe Asn
                 260                 265                 270

 Met Glu Phe Arg Asp Asn Pro Gly Asn Phe Val Lys Thr Glu Glu
                 275                 280                 285

 Thr Leu Phe Glu Ile Gln Gly Ile Asp Pro Ile Ala Ser Ala Ile
                 290                 295                 300

 Gln Asn Leu Lys Thr Thr Asp Lys Thr Lys Pro Ser Asn Leu Val
                 305                 310                 315

 Asn Thr Cys Ile Arg Thr Thr Leu Asp Arg Ala Ala Cys Leu Pro
                 320                 325                 330

 Pro Gly Asp His Asn Ala Leu Tyr Val Asn Ser Phe Pro Leu Leu
                 335                 340                 345

 Asp Pro Ser Asp Ala Pro Phe Pro Ser Leu Asp Ser Pro Gly Lys
                 350                 355                 360

 Ala Ile Arg Gly Pro Gln Gln Pro Ile Trp Lys Pro Phe Pro Asn
                 365                 370                 375

 Gln Asp Ser Asp Ser Val Val Leu Ser Gly Thr Asp Ser Glu Leu
                 380                 385                 390

 His Ile Pro Arg Val Cys Glu Phe Cys Gln Ala Val Phe Pro Pro
                 395                 400                 405

 Ser Ile Thr Ser Arg Gly Asp Phe Leu Arg His Leu Asn Ser His
                 410                 415                 420

 Phe Asn Gly Glu Thr
                 425

<210> 2016
<211> 2514
<212> DNA
<213> Homo sapien

<400> 2016
 cacgagggtg aattctgccc tggacagggc tttgcccttg gaggatcccc 50

 aggtggcctt acccgtgatt cttactcggc atcctccatt ccccaaactc 100

 cctcctccct gttaaatgtc aacctagacc tggacctggg tgggaggaaa 150

 ctgtagcctg agtgtccaca gggacacacg tgagccacag ggctagaagc 200

 acaggcccgt caccccagga ggaaaagccc agggtctggg gcagcagagc 250

 catcgcatca tgtttcccag ggcaacttga ggtctgactt ttggctccct 300

 cgccctaaga ggctcttcct ctcttttgct catccacctt cacaccactt 350

 gtgagctgac ccccaggaac agcttggctg ttccaccaga gcagagggaa 400

 tcattgctgg actggatttc ttctggaggg aagcaccatg aattaaaggt 450

 gccagagctc catgcatgga aaagtggcct gttggttcaa cgtggtttcc 500

 ttgtacttga tcctcctgaa atgagagatt ttcctgagat gactgagtat 550

 ggagattacc aggcagatga taccgaaatg cttaaagggg ctgtggctga 600

 ggctgtagca tctctgctgg aggtgagaca ctctgggaac tgatttgacc 650

 tcgaatgctc ctaaaagaga acttgatagc ctgacagcag agaagtatta 700

 tttggtgggg agtctgagaa agcctggctt gtattatctg tccaaaagga 750

 agcctcttca tctcctggtg ccttggttga ctattttgga aataggcata 800

 tcaaggttcc tgattcagca ctttgctctt ttaataacaa atcgtccaaa 850

 gatctcaaag taagggtttt tttttttagc ttccactctt ccgcagactt 900

 ggtcatcgac ctatttttgt tgaagaatga aaggcaatga caagtttaac 950

 atatacaaat tcgtgaattc ttgttcattt tgcattcctg cagtcagtgc 1000

 taatccgtcg ttcttaatca ggagttctgc caggtttaag gtcacctgca 1050

 ctcccagcca agtggtgatg tatgcctccc actctctgca aggttttcct 1100

 catttttata ttcatttatt catcattcat tcattcacct aactttcatt 1150

 aaatagctgc accatcccag gccctgtgcg gatcgggaat acaaagatga 1200

 gataaaacat tgtccctgcc cccgggggct tcacatgcca ctggaaacaa 1250

 cagactctta aactaacaat tcaagcaggc gccaagtgct acgacagagg 1300

 tgtgaataaa agcatcagga aatcggatgg agaaccacca ttcacccaag 1350

 ggtcagagga ggtttcaaag aaaaggtgtc attggagcag tgttttgcag 1400

 aatgagccag agttcaccaa gcaggcaagg caaggaaggg tgttgcagag 1450

 agggaacagc atatgcaaag gcatatcagt tcatggcatc acatctttca 1500

 ctggggaagc cagtttccac aggcagcatc ccaaggttca ataaggcctt 1550

 atttaacaag caagcaaaat gcaaaccaaa ccattattca tttattggct 1600

 taagtatgct ttctcctgaa aactttagca ttgggtgcaa atattcagta 1650

 tggttctcgg agtccaaagg gttttaagcc agggcacaac cagaaaagtg 1700

 gctctctttg gtagggagag gggctccaat atttcgttct ctccccatgg 1750

 ggcactgaca gagaaatgaa atagttttat ctggaaaatt ccagagctat 1800

 tatttactcc ttaccaaggg aagttacttc ttgtaaaaac ttttaagcca 1850

 tttatcaaca agttcttgtt gactcagggc ataatgagtt cctgagacat 1900

 gctcttttgg gggctggggc tttaggtaga agaatttcaa ggaaaagaat 1950

 tctcagcaga gctcaagatt gtagaaactc agcagaagct ggtaaaaaca 2000

 tggggagccc ggaggacagg ctgctgtcca gggcagaggc catgaagaag 2050

 tgcttccgtg gccgacagtc tggaaatgaa tccatcatac attagtgcca 2100

 tagagtttag taaccgtcca gcaagtgtca tcacttttac agaaaacaag 2150

 gtccagtaat agcaagtctt agtacatcct cacttttatt ataaatgggt 2200

 gttttttcat aatttttact gacgctcagt aaccatgcaa aattgtgtat 2250

 agcattaatg tatctacata cctacaccta tctatatata agctcatggt 2300

 agaaaaccat agctaagtag catcgcagac ttaagcgtac aaagtgatct 2350

 tgttcacaag taatctgttg acagtgccaa taaatgataa aaaaaaaatt 2400

 aacatgtcac aatgtaacgg atgaccatat gcacaattcc atgaattaaa 2450

 tctgtttcct gtgttagtca gtattcttaa ataaaattta taattgaaaa 2500

 aaaaaaaaaa aaaa 2514

<210> 2017
<211> 116
<212> PRT
<213> Homo sapien

<400> 2017
 Met Glu Asn His His Ser Pro Lys Gly Gln Arg Arg Phe Gln Arg
   1               5                  10                  15

 Lys Gly Val Ile Gly Ala Val Phe Cys Arg Met Ser Gln Ser Ser
                  20                  25                  30

 Pro Ser Arg Gln Gly Lys Glu Gly Cys Cys Arg Glu Gly Thr Ala
                  35                  40                  45

 Tyr Ala Lys Ala Tyr Gln Phe Met Ala Ser His Leu Ser Leu Gly
                  50                  55                  60

 Lys Pro Val Ser Thr Gly Ser Ile Pro Arg Phe Asn Lys Ala Leu
                  65                  70                  75

 Phe Asn Lys Gln Ala Lys Cys Lys Pro Asn His Tyr Ser Phe Ile
                  80                  85                  90

 Gly Leu Ser Met Leu Ser Pro Glu Asn Phe Ser Ile Gly Cys Lys
                  95                 100                 105

 Tyr Ser Val Trp Phe Ser Glu Ser Lys Gly Phe
                 110                 115

<210> 2018
<211> 2514
<212> DNA
<213> Homo sapien

<400> 2018
 cacgagggtg aattctgccc tggacagggc tttgcccttg gaggatcccc 50

 aggtggcctt acccgtgatt cttactcggc atcctccatt ccccaaactc 100

 cctcctccct gttaaatgtc aacctagacc tggacctggg tgggaggaaa 150

 ctgtagcctg agtgtccaca gggacacacg tgagccacag ggctagaagc 200

 acaggcccgt caccccagga ggaaaagccc agggtctggg gcagcagagc 250

 catcgcatca tgtttcccag ggcaacttga ggtctgactt ttggctccct 300

 cgccctaaga ggctcttcct ctcttttgct catccacctt cacaccactt 350

 gtgagctgac ccccaggaac agcttggctg ttccaccaga gcagagggaa 400

 tcattgctgg actggatttc ttctggaggg aagcaccatg aattaaaggt 450

 gccagagctc catgcatgga aaagtggcct gttggttcaa cgtggtttcc 500

 ttgtacttga tcctcctgaa atgagagatt ttcctgagat gactgagtat 550

 ggagattacc aggcagatga taccgaaatg cttaaagggg ctgtggctga 600

 ggctgtagca tctctgctgg aggtgagaca ctctgggaac tgatttgacc 650

 tcgaatgctc ctaaaagaga acttgatagc ctgacagcag agaagtatta 700

 tttggtgggg agtctgagaa agcctggctt gtattatctg tccaaaagga 750

 agcctcttca tctcctggtg ccttggttga ctattttgga aataggcata 800

 tcaaggttcc tgattcagca ctttgctctt ttaataacaa atcgtccaaa 850

 gatctcaaag taagggtttt tttttttagc ttccactctt ccgcagactt 900

 ggtcatcgac ctatttttgt tgaagaatga aaggcaatga caagtttaac 950

 atatacaaat tcgtgaattc ttgttcattt tgcattcctg cagtcagtgc 1000

 taatccgtcg ttcttaatca ggagttctgc caggtttaag gtcacctgca 1050

 ctcccagcca agtggtgatg tatgcctccc actctctgca aggttttcct 1100

 catttttata ttcatttatt catcattcat tcattcacct aactttcatt 1150

 aaatagctgc accatcccag gccctgtgcg gatcgggaat acaaagatga 1200

 gataaaacat tgtccctgcc cccgggggct tcacatgcca ctggaaacaa 1250

 cagactctta aactaacaat tcaagcaggc gccaagtgct acgacagagg 1300

 tgtgaataaa agcatcagga aatcggatgg agaaccacca ttcacccaag 1350

 ggtcagagga ggtttcaaag aaaaggtgtc attggagcag tgttttgcag 1400

 aatgagccag agttcaccaa gcaggcaagg caaggaaggg tgttgcagag 1450

 agggaacagc atatgcaaag gcatatcagt tcatggcatc acatctttca 1500

 ctggggaagc cagtttccac aggcagcatc ccaaggttca ataaggcctt 1550

 atttaacaag caagcaaaat gcaaaccaaa ccattattca tttattggct 1600

 taagtatgct ttctcctgaa aactttagca ttgggtgcaa atattcagta 1650

 tggttctcgg agtccaaagg gttttaagcc agggcacaac cagaaaagtg 1700

 gctctctttg gtagggagag gggctccaat atttcgttct ctccccatgg 1750

 ggcactgaca gagaaatgaa atagttttat ctggaaaatt ccagagctat 1800

 tatttactcc ttaccaaggg aagttacttc ttgtaaaaac ttttaagcca 1850

 tttatcaaca agttcttgtt gactcagggc ataatgagtt cctgagacat 1900

 gctcttttgg gggctggggc tttaggtaga agaatttcaa ggaaaagaat 1950

 tctcagcaga gctcaagatt gtagaaactc agcagaagct ggtaaaaaca 2000

 tggggagccc ggaggacagg ctgctgtcca gggcagaggc catgaagaag 2050

 tgcttccgtg gccgacagtc tggaaatgaa tccatcatac attagtgcca 2100

 tagagtttag taaccgtcca gcaagtgtca tcacttttac agaaaacaag 2150

 gtccagtaat agcaagtctt agtacatcct cacttttatt ataaatgggt 2200

 gttttttcat aatttttact gacgctcagt aaccatgcaa aattgtgtat 2250

 agcattaatg tatctacata cctacaccta tctatatata agctcatggt 2300

 agaaaaccat agctaagtag catcgcagac ttaagcgtac aaagtgatct 2350

 tgttcacaag taatctgttg acagtgccaa taaatgataa aaaaaaaatt 2400

 aacatgtcac aatgtaacgg atgaccatat gcacaattcc atgaattaaa 2450

 tctgtttcct gtgttagtca gtattcttaa ataaaattta taattgaaaa 2500

 aaaaaaaaaa aaaa 2514

<210> 2019
<211> 116
<212> PRT
<213> Homo sapien

<400> 2019
 Met Glu Asn His His Ser Pro Lys Gly Gln Arg Arg Phe Gln Arg
   1               5                  10                  15

 Lys Gly Val Ile Gly Ala Val Phe Cys Arg Met Ser Gln Ser Ser
                  20                  25                  30

 Pro Ser Arg Gln Gly Lys Glu Gly Cys Cys Arg Glu Gly Thr Ala
                  35                  40                  45

 Tyr Ala Lys Ala Tyr Gln Phe Met Ala Ser His Leu Ser Leu Gly
                  50                  55                  60

 Lys Pro Val Ser Thr Gly Ser Ile Pro Arg Phe Asn Lys Ala Leu
                  65                  70                  75

 Phe Asn Lys Gln Ala Lys Cys Lys Pro Asn His Tyr Ser Phe Ile
                  80                  85                  90

 Gly Leu Ser Met Leu Ser Pro Glu Asn Phe Ser Ile Gly Cys Lys
                  95                 100                 105

 Tyr Ser Val Trp Phe Ser Glu Ser Lys Gly Phe
                 110                 115

<210> 2020
<211> 1550
<212> DNA
<213> Homo sapien

<400> 2020
 ggcacgaggg ggaaggcaag atggcggcgc ccatggaggt ggccgtgtgt 50

 acggactcgg cggccccgat gtggagctgc atcgtgtggg aacttcactc 100

 gggcgccaac ctgctcacct accgcggcgg ccaggcggga ccccgcggcc 150

 tggcgctgct caatggcgag tatctgctgg cggcgcagct gggcaagaac 200

 tacatcagcg cctgggagct gcagcggaag gaccagctcc agcagaagat 250

 catgtgcccc gggcctgtca cctgtctgac tgcatcaccc aatggtctct 300

 acgtcctggc aggagttgca gaaagcatcc acctgtggga ggtctccacc 350

 gggaaccttc tggtcatcct gagtcgacac taccaggacg tctcctgcct 400

 tcagttcaca ggggacagca gccacttcat ctcagggggc aaggactgcc 450

 tggtgctggt ttggagcctc tgcagcgtgc tgcaggccga cccctccagg 500

 attccggcgc ccaggcacgt ctggtctcac cacacgctcc ccatcacgga 550

 cctgcactgc ggctttgggg gccccctggc ccgggtggcc acctcctcac 600

 tggaccagac ggtgaagcta tgggaggtct cctcggggga gctgctgctc 650

 tccgtcctct ttgacgtgtc catcatggca gtgaccatgg acctggctga 700

 gcaccatatg ttctgcgggg gcagtgaggg ctccatcttc caggtcgacc 750

 tcttcacctg gcccggacag agggagagga gcttccaccc agagcaggac 800

 gccgggaagg tcttcaaagg gcacaggaac caggtgactt gcctgtcagt 850

 gtccactgac ggcagcgtgc tgctctcagg ctcccacgac gagaccgtgc 900

 gcctctggga cgtgcagagc aagcagtgca tccggacggt ggccctcaaa 950

 ggcccagtca ccaatgccgc catcctgctg gcgcccgtca gcatgctgag 1000

 ctcagacttc aggcccagcc tgccgctgcc ccacttcaac aagcacctgc 1050

 tgggcgccga gcacggggac gagccgcgcc acgggggcct cactctgcgc 1100

 ctgggcctcc accagcaggg ctcggagccc agctacctgg accgcacgga 1150

 gcagctgcag gccgtcctgt gcagcaccat ggagaagagc gtgctcggcg 1200

 gccaggacca gctgcgcgtc cgtgtgacgg agctggagga cgaggtgcgc 1250

 aacctgcgca agatcaatcg ggacctgttc gacttctcca cgcgcttcat 1300

 cacgcggccg gccaagtgag gcccggagac cccggcccga ggcgcccagg 1350

 cctgagcccc atgcctccca gcaaccaggg cccgcgggtg tggcccccac 1400

 cagcccaggc ctggactctc ctcagttctg tgtcgtgttc gggtttttcc 1450

 tctgtgactg ggccgtcttg gtgtctcgtg gcacgcgtca cagtggtgct 1500

 agtctgtttt taacaaaaga ggatgaaaag ccaaaaaaaa aaaaaaaaaa 1550

<210> 2021
<211> 438
<212> PRT
<213> Homo sapien

<400> 2021
 His Glu Gly Glu Gly Lys Met Ala Ala Pro Met Glu Val Ala Val
   1               5                  10                  15

 Cys Thr Asp Ser Ala Ala Pro Met Trp Ser Cys Ile Val Trp Glu
                  20                  25                  30

 Leu His Ser Gly Ala Asn Leu Leu Thr Tyr Arg Gly Gly Gln Ala
                  35                  40                  45

 Gly Pro Arg Gly Leu Ala Leu Leu Asn Gly Glu Tyr Leu Leu Ala
                  50                  55                  60

 Ala Gln Leu Gly Lys Asn Tyr Ile Ser Ala Trp Glu Leu Gln Arg
                  65                  70                  75

 Lys Asp Gln Leu Gln Gln Lys Ile Met Cys Pro Gly Pro Val Thr
                  80                  85                  90

 Cys Leu Thr Ala Ser Pro Asn Gly Leu Tyr Val Leu Ala Gly Val
                  95                 100                 105

 Ala Glu Ser Ile His Leu Trp Glu Val Ser Thr Gly Asn Leu Leu
                 110                 115                 120

 Val Ile Leu Ser Arg His Tyr Gln Asp Val Ser Cys Leu Gln Phe
                 125                 130                 135

 Thr Gly Asp Ser Ser His Phe Ile Ser Gly Gly Lys Asp Cys Leu
                 140                 145                 150

 Val Leu Val Trp Ser Leu Cys Ser Val Leu Gln Ala Asp Pro Ser
                 155                 160                 165

 Arg Ile Pro Ala Pro Arg His Val Trp Ser His His Thr Leu Pro
                 170                 175                 180

 Ile Thr Asp Leu His Cys Gly Phe Gly Gly Pro Leu Ala Arg Val
                 185                 190                 195

 Ala Thr Ser Ser Leu Asp Gln Thr Val Lys Leu Trp Glu Val Ser
                 200                 205                 210

 Ser Gly Glu Leu Leu Leu Ser Val Leu Phe Asp Val Ser Ile Met
                 215                 220                 225

 Ala Val Thr Met Asp Leu Ala Glu His His Met Phe Cys Gly Gly
                 230                 235                 240

 Ser Glu Gly Ser Ile Phe Gln Val Asp Leu Phe Thr Trp Pro Gly
                 245                 250                 255

 Gln Arg Glu Arg Ser Phe His Pro Glu Gln Asp Ala Gly Lys Val
                 260                 265                 270

 Phe Lys Gly His Arg Asn Gln Val Thr Cys Leu Ser Val Ser Thr
                 275                 280                 285

 Asp Gly Ser Val Leu Leu Ser Gly Ser His Asp Glu Thr Val Arg
                 290                 295                 300

 Leu Trp Asp Val Gln Ser Lys Gln Cys Ile Arg Thr Val Ala Leu
                 305                 310                 315

 Lys Gly Pro Val Thr Asn Ala Ala Ile Leu Leu Ala Pro Val Ser
                 320                 325                 330

 Met Leu Ser Ser Asp Phe Arg Pro Ser Leu Pro Leu Pro His Phe
                 335                 340                 345

 Asn Lys His Leu Leu Gly Ala Glu His Gly Asp Glu Pro Arg His
                 350                 355                 360

 Gly Gly Leu Thr Leu Arg Leu Gly Leu His Gln Gln Gly Ser Glu
                 365                 370                 375

 Pro Ser Tyr Leu Asp Arg Thr Glu Gln Leu Gln Ala Val Leu Cys
                 380                 385                 390

 Ser Thr Met Glu Lys Ser Val Leu Gly Gly Gln Asp Gln Leu Arg
                 395                 400                 405

 Val Arg Val Thr Glu Leu Glu Asp Glu Val Arg Asn Leu Arg Lys
                 410                 415                 420

 Ile Asn Arg Asp Leu Phe Asp Phe Ser Thr Arg Phe Ile Thr Arg
                 425                 430                 435

 Pro Ala Lys


<210> 2022
<211> 4444
<212> DNA
<213> Homo sapien

<400> 2022
 acggagacgg accacagcaa gcagaggctg ggggggggaa agacgaggaa 50

 agaggaggaa aacaaaagct gctacttatg gaagatacaa aggagtctaa 100

 cgtgaagaca ttttgctcca agaatatcct agccatcctt ggcttctcct 150

 ctatcatagc tgtgatagct ttgcttgctg tggggttgac ccagaacaaa 200

 gcattgccag aaaacgttaa gtatgggatt gtgctggatg cgggttcttc 250

 tcacacaagt ttatacatct ataagtggcc agcagaaaag gagaatgaca 300

 caggcgtggt gcatcaagta gaagaatgca gggttaaagg tcctggaatc 350

 tcaaaatttg ttcagaaagt aaatgaaata ggcatttacc tgactgattg 400

 catggaaaga gctagggaag tgattccaag gtcccagcac caagagacac 450

 ccgtttacct gggagccacg gcaggcatgc ggttgctcag gatggaaagt 500

 gaagagttgg cagacagggt tctggatgtg gtggagagga gcctcagcaa 550

 ctaccccttt gacttccagg gtgccaggat cattactggc caagaggaag 600

 gtgcctatgg ctggattact atcaactatc tgctgggcaa attcagtcag 650

 aaaacaaggt ggttcagcat agtcccatat gaaaccaata atcaggaaac 700

 ctttggagct ttggaccttg ggggagcctc tacacaagtc acttttgtac 750

 cccaaaacca gactatcgag tccccagata atgctctgca atttcgcctc 800

 tatggcaagg actacaatgt ctacacacat agcttcttgt gctatgggaa 850

 ggatcaggca ctctggcaga aactggccaa ggacattcag gttgcaagta 900

 atgaaattct cagggaccca tgctttcatc ctggatataa gaaggtagtg 950

 aacgtaagtg acctttacaa gaccccctgc accaagagat ttgagatgac 1000

 tcttccattc cagcagtttg aaatccaggg tattggaaac tatcaacaat 1050

 gccatcaaag catcctggag ctcttcaaca ccagttactg cccttactcc 1100

 cagtgtgcct tcaatgggat tttcttgcca ccactccagg gggattttgg 1150

 ggcattttca gctttttact ttgtgatgaa gtttttaaac ttgacatcag 1200

 agaaagtctc tcaggaaaag gtgactgaga tgatgaaaaa gttctgtgct 1250

 cagccttggg aggagataaa aacatcttac gctggagtaa aggagaagta 1300

 cctgagtgaa tactgctttt ctggtaccta cattctctcc ctccttctgc 1350

 aaggctatca tttcacagct gattcctggg agcacatcca tttcattggc 1400

 aagatccagg gcagcgacgc cggctggact ttgggctaca tgctgaacct 1450

 gaccaacatg atcccagctg agcaaccatt gtccacacct ctctcccact 1500

 ccacctatgt cttcctcatg gttctattct ccctggtcct tttcacagtg 1550

 gccatcatag gcttgcttat ctttcacaag ccttcatatt tctggaaaga 1600

 tatggtatag caaaagcagc tgaaatatgc tggctggagt gaggaaaaaa 1650

 atcgtccagg gagcattttc ctccatcgca gtgttcaagg ccatccttcc 1700

 ctgtctgcca gggccagtct tgacgagtgt gaagcttcct tggcttttac 1750

 tgaagccttt cttttggagg tattcaatat cctttgcctc aaggacttcg 1800

 gcagatactg tctctttcat gagtttttcc cagctacacc tttctccttt 1850

 gtactttgtg cttgtatagg ttttaaagac ctgacacctt tcataatctt 1900

 tgctttataa aagaacaata ttgactttgt ctagaagaac tgagagtctt 1950

 gagtcctgtg ataggaggct gagctggctg aaagaagaat ctcaggaact 2000

 ggttcagttg tactctttaa gaaccccttt ctctctcctg tttgccatcc 2050

 attaagaaag ccatatgatg cctttggaga aggcagacac acattccatt 2100

 cccagcctgc tctgtgggta ggagaatttt ctacagtagg caaatatgtg 2150

 ctaaagccaa agagttttat aaggaaatat atgtgctcat gcagtcaata 2200

 cagttctcaa tcccacccaa agcaggtatg tcaataaatc acatattcct 2250

 aggtgatacc caaatgctac agagtggaac actcagacct gagatttgca 2300

 aaaagcagat gtaaatatat gcattcaaac atcagggctt actatgaggt 2350

 aggtggtata tacatgtcac aaataaaaat acagttacaa ctcagggtca 2400

 caaaaaatgc atcttccaat gcatattttt attatggtaa aatatacata 2450

 aatataattc accattttaa catttaattc atattaaata cgtacaaatc 2500

 agtgacattt agtacattca cagtgttgtg ccaccatcac cactatttag 2550

 ttccagaaca tttgcatcat caatacattg tctagagaca agactatcct 2600

 gggtaggcag aaaccataga tcttttgtgt ttacagctat ggaaaccaac 2650

 tgtaccataa agatagttca ctgagtttta aagccaagcc acatcttatt 2700

 tttccaaggt ttaatttagt gagagggcag cattagtgtg gagtggcatg 2750

 cttttgccct atcgtggaat ttacacatca gaatgtgcag gatccaagtc 2800

 tgaaagtgtt gccacccgtc acacaacatg ggctttgttt gcttattcca 2850

 tgaagcagca gctatagacc ttaccatgga aacatgaaga gaccctgcac 2900

 ccctttcctt aaggattgct gcaagagtta cctgttgagc aggattgact 2950

 ggtgatgttt cattctgacc ttgtcccaag ctctccatct ctagatctgg 3000

 ggactgactg ttgagctgat ggggaaagaa aagctctcac acaaaccgga 3050

 agccaaatgt cccctatctc ttgaatgatc aagtcacttt tgacaacatc 3100

 caggtgaata taaaaactta ataaagctgt ggaaaggaac tcttaatctt 3150

 cttttctgct acttaggtta aattcactag atcttgatta ggaatcaaaa 3200

 ttcgaattgg gacatgttca aattctttct tgtggtagtt gcctatactg 3250

 tcatcgctgc tgttggttga gcatttgtgg tgtaccacgc tgtgtgctca 3300

 agggtattac attcatcttc tcatttaatc ctcacaacaa tctgaagaag 3350

 gtaggtatta caattcccac ttcatagaaa cagaaactga ggttcagaga 3400

 ggttaagtca tttgcccaaa tggctgagcc aaagcctacc atgtacctaa 3450

 cctttatttt ctttcccgaa cataccaggc tgtctcctca taacttccaa 3500

 gcatgcactt aaaactccac atgaatacaa ggttcatggg acttggtatt 3550

 catagaaagg gaggcagaaa gctggtctgt tcctgatagg cttgtaattt 3600

 aatatcattc tgttcatgtg ctttggatgg aagcacatct ggcatatgat 3650

 gctaatcagt ggttcccata cccctggctt cctaatttta atgtttgctc 3700

 acagcatagt agattgacat caaatagtgg ccgatgatga tgaaaataaa 3750

 ggtcaaataa gttgagccaa taacagccgc ttttttcctt ctgtctgcgt 3800

 atacaaagca ctgtcatgca cacaatctat tctgaccctc acaacaaccc 3850

 ataagggtgt aaatagtatt tccattttac aaatgaggat cacacaaact 3900

 actacatggc agagcagata ctccaactca tgtcttctgg ttgaagccta 3950

 ttgctttttc ttttctaaac actttccctc agcaagttgg aattagactt 4000

 cacaagtctc cttcagagaa cacaaatctt ttcttattcc attcctgttt 4050

 ggttgcctac gtccaatctc cccctcccca gagatgccaa aaaaaaaatc 4100

 ctttaaggta tttgggagcc aaactcaact tgttaaaatc tcaaattatg 4150

 gagacaatca gcagacacaa cctaacccca attattttgg caggaaggtt 4200

 ggtttagagg cagatccagc aatctgcttt gggccactct gggtggggta 4250

 ggtgaaataa gattggtcac tgttaactaa ttttaatatt ggattggcca 4300

 ttggttatca ctgattacca ttctcccctg gattttcacc caggactcaa 4350

 aacttggttc tgctaaccct gttcctttat gaggaacctt ttaaagattc 4400

 ctttataagg tgggagtttt ttttctatga acctataggg gaga 4444

<210> 2023
<211> 535
<212> PRT
<213> Homo sapien

<400> 2023
 Gly Asp Gly Pro Gln Gln Ala Glu Ala Gly Gly Gly Lys Asp Glu
   1               5                  10                  15

 Glu Arg Gly Gly Lys Gln Lys Leu Leu Leu Met Glu Asp Thr Lys
                  20                  25                  30

 Glu Ser Asn Val Lys Thr Phe Cys Ser Lys Asn Ile Leu Ala Ile
                  35                  40                  45

 Leu Gly Phe Ser Ser Ile Ile Ala Val Ile Ala Leu Leu Ala Val
                  50                  55                  60

 Gly Leu Thr Gln Asn Lys Ala Leu Pro Glu Asn Val Lys Tyr Gly
                  65                  70                  75

 Ile Val Leu Asp Ala Gly Ser Ser His Thr Ser Leu Tyr Ile Tyr
                  80                  85                  90

 Lys Trp Pro Ala Glu Lys Glu Asn Asp Thr Gly Val Val His Gln
                  95                 100                 105

 Val Glu Glu Cys Arg Val Lys Gly Pro Gly Ile Ser Lys Phe Val
                 110                 115                 120

 Gln Lys Val Asn Glu Ile Gly Ile Tyr Leu Thr Asp Cys Met Glu
                 125                 130                 135

 Arg Ala Arg Glu Val Ile Pro Arg Ser Gln His Gln Glu Thr Pro
                 140                 145                 150

 Val Tyr Leu Gly Ala Thr Ala Gly Met Arg Leu Leu Arg Met Glu
                 155                 160                 165

 Ser Glu Glu Leu Ala Asp Arg Val Leu Asp Val Val Glu Arg Ser
                 170                 175                 180

 Leu Ser Asn Tyr Pro Phe Asp Phe Gln Gly Ala Arg Ile Ile Thr
                 185                 190                 195

 Gly Gln Glu Glu Gly Ala Tyr Gly Trp Ile Thr Ile Asn Tyr Leu
                 200                 205                 210

 Leu Gly Lys Phe Ser Gln Lys Thr Arg Trp Phe Ser Ile Val Pro
                 215                 220                 225

 Tyr Glu Thr Asn Asn Gln Glu Thr Phe Gly Ala Leu Asp Leu Gly
                 230                 235                 240

 Gly Ala Ser Thr Gln Val Thr Phe Val Pro Gln Asn Gln Thr Ile
                 245                 250                 255

 Glu Ser Pro Asp Asn Ala Leu Gln Phe Arg Leu Tyr Gly Lys Asp
                 260                 265                 270

 Tyr Asn Val Tyr Thr His Ser Phe Leu Cys Tyr Gly Lys Asp Gln
                 275                 280                 285

 Ala Leu Trp Gln Lys Leu Ala Lys Asp Ile Gln Val Ala Ser Asn
                 290                 295                 300

 Glu Ile Leu Arg Asp Pro Cys Phe His Pro Gly Tyr Lys Lys Val
                 305                 310                 315

 Val Asn Val Ser Asp Leu Tyr Lys Thr Pro Cys Thr Lys Arg Phe
                 320                 325                 330

 Glu Met Thr Leu Pro Phe Gln Gln Phe Glu Ile Gln Gly Ile Gly
                 335                 340                 345

 Asn Tyr Gln Gln Cys His Gln Ser Ile Leu Glu Leu Phe Asn Thr
                 350                 355                 360

 Ser Tyr Cys Pro Tyr Ser Gln Cys Ala Phe Asn Gly Ile Phe Leu
                 365                 370                 375

 Pro Pro Leu Gln Gly Asp Phe Gly Ala Phe Ser Ala Phe Tyr Phe
                 380                 385                 390

 Val Met Lys Phe Leu Asn Leu Thr Ser Glu Lys Val Ser Gln Glu
                 395                 400                 405

 Lys Val Thr Glu Met Met Lys Lys Phe Cys Ala Gln Pro Trp Glu
                 410                 415                 420

 Glu Ile Lys Thr Ser Tyr Ala Gly Val Lys Glu Lys Tyr Leu Ser
                 425                 430                 435

 Glu Tyr Cys Phe Ser Gly Thr Tyr Ile Leu Ser Leu Leu Leu Gln
                 440                 445                 450

 Gly Tyr His Phe Thr Ala Asp Ser Trp Glu His Ile His Phe Ile
                 455                 460                 465

 Gly Lys Ile Gln Gly Ser Asp Ala Gly Trp Thr Leu Gly Tyr Met
                 470                 475                 480

 Leu Asn Leu Thr Asn Met Ile Pro Ala Glu Gln Pro Leu Ser Thr
                 485                 490                 495

 Pro Leu Ser His Ser Thr Tyr Val Phe Leu Met Val Leu Phe Ser
                 500                 505                 510

 Leu Val Leu Phe Thr Val Ala Ile Ile Gly Leu Leu Ile Phe His
                 515                 520                 525

 Lys Pro Ser Tyr Phe Trp Lys Asp Met Val
                 530                 535

<210> 2024
<211> 2081
<212> DNA
<213> Homo sapien

<400> 2024
 cccgggtgta cgtgtaaaat tatgatcaaa taaatttgta tgccttttct 50

 cctattaacc tgcctttttt gtcagcgatt gtcagtgaaa cttcagaggg 100

 caaaggggaa gttttccttg gcccctccag ttttggtgct gtgaacagga 150

 taccaaagct gctctgttct tctggaagct gcaatgaagg gaaccaagga 200

 cctgacaagc cagcagaagg agtctaacgt gaagacattt tgctccaaga 250

 atatcctagc catccttggc ttctcctcta tcatagctgt gatagctttg 300

 cttgctgtgg ggttgaccca gaacaaagca ttgccagaaa acgttaagta 350

 tgggattgtg ctggatgcgg gttcttctca cacaagttta tacatctata 400

 agtggccagc agaaaaggag aatgacacag gcgtggtgca tcaagtagaa 450

 gaatgcaggg ttaaaggtcc tggaatctca aaatttgttc agaaagtaaa 500

 tgaaataggc atttacctga ctgattgcat ggaaagagct agggaagtga 550

 ttccaaggtc ccagcaccaa gagacacccg tttacctggg agccacggca 600

 ggcatgcggt tgctcaggat ggaaagtgaa gagttggcag acagggttct 650

 ggatgtggtg gagaggagcc tcagcaacta cccctttgac ttccagggtg 700

 ccaggatcat tactggccaa gaggaaggtg cctatggctg gattactatc 750

 aactatctgc tgggcaaatt cagtcagaaa acaaggtggt tcagcatagt 800

 cccatatgaa accaataatc aggaaacctt tggagctttg gaccttgggg 850

 gagcctctac acaagtcact tttgtacccc aaaaccagac tatcgagtcc 900

 ccagataatg ctctgcaatt tcgcctctat ggcaaggact acaatgtcta 950

 cacacatagc ttcttgtgct atgggaagga tcaggcactc tggcagaaac 1000

 tggccaagga cattcaggtt gcaagtaatg aaattctcag ggacccatgc 1050

 tttcatcctg gatataagaa ggtagtgaac gtaagtgacc tttacaagac 1100

 cccctgcacc aagagatttg agatgactct tccattccag cagtttgaaa 1150

 tccagggtat tggaaactat caacaatgcc atcaaagcat cctggagctc 1200

 ttcaacacca gttactgccc ttactcccag tgtgccttca atgggatttt 1250

 cttgccacca ctccaggggg attttggggc attttcagct ttttactttg 1300

 tgatgaagtt tttaaacttg acatcagaga aagtctctca ggaaaaggtg 1350

 actgagatga tgaaaaagtt ctgtgctcag ccttgggagg agataaaaac 1400

 atcttacgct ggagtaaagg agaagtacct gagtgaatac tgcttttctg 1450

 gtacctacat tctctccctc cttctgcaag gctatcattt cacagctgat 1500

 tcctgggagc acatccattt cattggcaag atccagggca gcgacgccgg 1550

 ctggactttg ggctacatgc tgaacctgac caacatgatc ccagctgagc 1600

 aaccattgtc cacacctctc tcccactcca cctatgtctt cctcatggtt 1650

 ctattctccc tggtcctttt cacagtggcc atcataggct tgcttatctt 1700

 tcacaagcct tcatatttct ggaaagatat ggtatagcaa aagcagctga 1750

 aatatgctgg ctggagtgag gaaaaaatcg tccagggagc attttcctcc 1800

 atcgcagtgt tcaaggccat ccttccctgt ctgccagggc cagtcttgac 1850

 gagtgtgaag cttccttggc ttttactgaa gcctttcttt tggaggtatt 1900

 caatatcctt tgcctcaagg acttcggcag atactgtctc tttcatgagt 1950

 ttttcccagc tacacctttc tcctttgtac tttgtgcttg tataggtttt 2000

 aaagacctga cacctttcat aatctttgct ttataaaaga acaatattga 2050

 ctttgtctag aaaaaaaaaa aaaaaaaaaa a 2081

<210> 2025
<211> 517
<212> PRT
<213> Homo sapien

<400> 2025
 Met Lys Gly Thr Lys Asp Leu Thr Ser Gln Gln Lys Glu Ser Asn
   1               5                  10                  15

 Val Lys Thr Phe Cys Ser Lys Asn Ile Leu Ala Ile Leu Gly Phe
                  20                  25                  30

 Ser Ser Ile Ile Ala Val Ile Ala Leu Leu Ala Val Gly Leu Thr
                  35                  40                  45

 Gln Asn Lys Ala Leu Pro Glu Asn Val Lys Tyr Gly Ile Val Leu
                  50                  55                  60

 Asp Ala Gly Ser Ser His Thr Ser Leu Tyr Ile Tyr Lys Trp Pro
                  65                  70                  75

 Ala Glu Lys Glu Asn Asp Thr Gly Val Val His Gln Val Glu Glu
                  80                  85                  90

 Cys Arg Val Lys Gly Pro Gly Ile Ser Lys Phe Val Gln Lys Val
                  95                 100                 105

 Asn Glu Ile Gly Ile Tyr Leu Thr Asp Cys Met Glu Arg Ala Arg
                 110                 115                 120

 Glu Val Ile Pro Arg Ser Gln His Gln Glu Thr Pro Val Tyr Leu
                 125                 130                 135

 Gly Ala Thr Ala Gly Met Arg Leu Leu Arg Met Glu Ser Glu Glu
                 140                 145                 150

 Leu Ala Asp Arg Val Leu Asp Val Val Glu Arg Ser Leu Ser Asn
                 155                 160                 165

 Tyr Pro Phe Asp Phe Gln Gly Ala Arg Ile Ile Thr Gly Gln Glu
                 170                 175                 180

 Glu Gly Ala Tyr Gly Trp Ile Thr Ile Asn Tyr Leu Leu Gly Lys
                 185                 190                 195

 Phe Ser Gln Lys Thr Arg Trp Phe Ser Ile Val Pro Tyr Glu Thr
                 200                 205                 210

 Asn Asn Gln Glu Thr Phe Gly Ala Leu Asp Leu Gly Gly Ala Ser
                 215                 220                 225

 Thr Gln Val Thr Phe Val Pro Gln Asn Gln Thr Ile Glu Ser Pro
                 230                 235                 240

 Asp Asn Ala Leu Gln Phe Arg Leu Tyr Gly Lys Asp Tyr Asn Val
                 245                 250                 255

 Tyr Thr His Ser Phe Leu Cys Tyr Gly Lys Asp Gln Ala Leu Trp
                 260                 265                 270

 Gln Lys Leu Ala Lys Asp Ile Gln Val Ala Ser Asn Glu Ile Leu
                 275                 280                 285

 Arg Asp Pro Cys Phe His Pro Gly Tyr Lys Lys Val Val Asn Val
                 290                 295                 300

 Ser Asp Leu Tyr Lys Thr Pro Cys Thr Lys Arg Phe Glu Met Thr
                 305                 310                 315

 Leu Pro Phe Gln Gln Phe Glu Ile Gln Gly Ile Gly Asn Tyr Gln
                 320                 325                 330

 Gln Cys His Gln Ser Ile Leu Glu Leu Phe Asn Thr Ser Tyr Cys
                 335                 340                 345

 Pro Tyr Ser Gln Cys Ala Phe Asn Gly Ile Phe Leu Pro Pro Leu
                 350                 355                 360

 Gln Gly Asp Phe Gly Ala Phe Ser Ala Phe Tyr Phe Val Met Lys
                 365                 370                 375

 Phe Leu Asn Leu Thr Ser Glu Lys Val Ser Gln Glu Lys Val Thr
                 380                 385                 390

 Glu Met Met Lys Lys Phe Cys Ala Gln Pro Trp Glu Glu Ile Lys
                 395                 400                 405

 Thr Ser Tyr Ala Gly Val Lys Glu Lys Tyr Leu Ser Glu Tyr Cys
                 410                 415                 420

 Phe Ser Gly Thr Tyr Ile Leu Ser Leu Leu Leu Gln Gly Tyr His
                 425                 430                 435

 Phe Thr Ala Asp Ser Trp Glu His Ile His Phe Ile Gly Lys Ile
                 440                 445                 450

 Gln Gly Ser Asp Ala Gly Trp Thr Leu Gly Tyr Met Leu Asn Leu
                 455                 460                 465

 Thr Asn Met Ile Pro Ala Glu Gln Pro Leu Ser Thr Pro Leu Ser
                 470                 475                 480

 His Ser Thr Tyr Val Phe Leu Met Val Leu Phe Ser Leu Val Leu
                 485                 490                 495

 Phe Thr Val Ala Ile Ile Gly Leu Leu Ile Phe His Lys Pro Ser
                 500                 505                 510

 Tyr Phe Trp Lys Asp Met Val
                 515

<210> 2026
<211> 878
<212> DNA
<213> Homo sapien

<400> 2026
 gcgcgggcag ggccgcacga gctggctggc tgcttgcacc cacatccttc 50

 tttctctggg acctggggtc gcggttactt gggctggccg gcgaaccctt 100

 gagtggcctg gcggggagcg ggcctcgcgc gcctggaggg ccctgtggaa 150

 cgaagagagg cacacagcat ggcagaaaac cgagagcccc gcggtgctgt 200

 ggaggctgaa ctggatccag tggaatacac ccttaggaaa aggcttccca 250

 gccgcttgcc ccggagaccc aatgacattt atgtcaacat gaagacggac 300

 tttaaggccc agctggcccg ctgccagaag ctgctggacg gaggggcccg 350

 gggtcagaac gcgtgctctg agatctacat tcacggcttg ggcctggcca 400

 tcaaccacgc catcaacatc gcgctgcagc tgcaggcggg cagcttcggg 450

 tccttgcagg tggctgccaa tacctccacc gtggagcttg ttgatgagct 500

 ggagccagag accgacacac gggagccact gactcggatc cgcaacaact 550

 cagccatcca catccgagtc ttcagggtca cacccaagta attgaaaaga 600

 cactcctcca cttatcccct ccgtgatatg gctcttcgca tgctgagtac 650

 tggacctcgg accagagcca tgtaagaaaa ggcctgttcc ctggaagccc 700

 aaaggactct gcattgaggg tgggggtaat tgtctcttgg tggcccagtt 750

 agtgggcctt cctgagtgtg tgtatgcggt ctgtaactat tgccatataa 800

 ataaaaaatc ctgttgcact agtgtcctgc caaaaaaaaa aaaaaaaaaa 850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaa 878

<210> 2027
<211> 140
<212> PRT
<213> Homo sapien

<400> 2027
 Met Ala Glu Asn Arg Glu Pro Arg Gly Ala Val Glu Ala Glu Leu
   1               5                  10                  15

 Asp Pro Val Glu Tyr Thr Leu Arg Lys Arg Leu Pro Ser Arg Leu
                  20                  25                  30

 Pro Arg Arg Pro Asn Asp Ile Tyr Val Asn Met Lys Thr Asp Phe
                  35                  40                  45

 Lys Ala Gln Leu Ala Arg Cys Gln Lys Leu Leu Asp Gly Gly Ala
                  50                  55                  60

 Arg Gly Gln Asn Ala Cys Ser Glu Ile Tyr Ile His Gly Leu Gly
                  65                  70                  75

 Leu Ala Ile Asn His Ala Ile Asn Ile Ala Leu Gln Leu Gln Ala
                  80                  85                  90

 Gly Ser Phe Gly Ser Leu Gln Val Ala Ala Asn Thr Ser Thr Val
                  95                 100                 105

 Glu Leu Val Asp Glu Leu Glu Pro Glu Thr Asp Thr Arg Glu Pro
                 110                 115                 120

 Leu Thr Arg Ile Arg Asn Asn Ser Ala Ile His Ile Arg Val Phe
                 125                 130                 135

 Arg Val Thr Pro Lys
                 140

<210> 2028
<211> 1622
<212> DNA
<213> Homo sapien

<400> 2028
 ggcacgagga agctactcag ataagaggct ccaagaggac atttttggat 50

 gtgaaaaaca atgagaagga ggacaacaca catttacaat cgtcttaatt 100

 ttgtactcag aaaaaggatg tgaagacaat gcacagggaa tacaatagtt 150

 tcagatctgt gtacagtttc cttttgcttc atctcctgca acaatgtaat 200

 gaagacacca tgatatcatt aacatttcac acaaaaggaa aatgaggctg 250

 aaatggtgtg ggcaaggccc aggaatctgg agcatcccta accaagcagc 300

 agagcacctg ggatagagaa agtgctcaag aatgttcact tactgattac 350

 tacaatcaaa aaaagatacg acactaattt accacattct tcttacttat 400

 tttatgagat actattcttc caaggtggag aaagtggaga aagtagagtg 450

 acgcagctaa gggagtaaat cgaccctcag ccaacaagtg gcaaaagcct 500

 gaagaaagtg atcaagatca ctgatgaccc cgcggcccat ctccaagggg 550

 gcgggtatca caaccccgac gccacaccac gtatcattcc gcaaaactcc 600

 cgcgcctccc acgcagaact ggcaagaggg aaggcgagac agcagtgaac 650

 agctggtacg cagcacccac agcaccgcgg cagcagctag tgccgactcc 700

 cgcctagctc ttttgactct gttcgcggga agaatgggga aacagtaagg 750

 ttgcggcgcc tcccgcgaga cgaggtacct gaggctggcc ccgcagtccc 800

 ccgccgcacc agcaccggag cttcacaccc cacttccggg gtcaagtcac 850

 cgccgggaat cctgtgatcg cagaaaggta gtctcaggtt ccgcccctat 900

 ccaagtcccg cctccactgc ctctcgccct gtatctgtca acttccggga 950

 cgccgcgcgt cactaagcag ccaatctcca cttccggact catccagccc 1000

 cttctccacc cctttcagag acagcgcgat tgcgatttag gtttccgcgc 1050

 atttaattgg cgaagctgga gcgctagtct tcgctgattg gtgccgagaa 1100

 atctgcccca tagacacccg cggggcgcac agtttcagtc gtccgtgggt 1150

 ttcccgccag ccgcagtctt ggaccataat catggtggac atgatggact 1200

 tgcccaggtc gcgcatcaac gccggcatgc tagctcaatt catcgacaag 1250

 cctgtctgct tcgtagggag gctggaaaag attcatccca ccggaaaaat 1300

 gtttattctt tcagatggag aaggaaaaaa tggaaccatc gagttgatgg 1350

 aaccccttga tgaagaaatc tctggaattg tggaagtggt tggaagagta 1400

 accgccaagg ccaccatctt gtgtacatct tatgtccagt ttaaagaaga 1450

 tagccatcct tttgatcttg gactttacaa tgaagctgtg aaaattatcc 1500

 atgacttccc tcagttttat cctttaggga ttgtgcaaca tgattgatct 1550

 tgatggattt tcatacgatt gtaaatgagc tatattaaag tctattaaag 1600

 gaaaaaaaaa aaaaaaaaaa aa 1622

<210> 2029
<211> 121
<212> PRT
<213> Homo sapien

<400> 2029
 Met Val Asp Met Met Asp Leu Pro Arg Ser Arg Ile Asn Ala Gly
   1               5                  10                  15

 Met Leu Ala Gln Phe Ile Asp Lys Pro Val Cys Phe Val Gly Arg
                  20                  25                  30

 Leu Glu Lys Ile His Pro Thr Gly Lys Met Phe Ile Leu Ser Asp
                  35                  40                  45

 Gly Glu Gly Lys Asn Gly Thr Ile Glu Leu Met Glu Pro Leu Asp
                  50                  55                  60

 Glu Glu Ile Ser Gly Ile Val Glu Val Val Gly Arg Val Thr Ala
                  65                  70                  75

 Lys Ala Thr Ile Leu Cys Thr Ser Tyr Val Gln Phe Lys Glu Asp
                  80                  85                  90

 Ser His Pro Phe Asp Leu Gly Leu Tyr Asn Glu Ala Val Lys Ile
                  95                 100                 105

 Ile His Asp Phe Pro Gln Phe Tyr Pro Leu Gly Ile Val Gln His
                 110                 115                 120

 Asp


<210> 2030
<211> 2496
<212> DNA
<213> Homo sapien

<400> 2030
 gttttgaaag ttgatggagc gaactgcttt tccaaagact cttttgaaaa 50

 actttttaag taggccattc tgactttaac atttctcttt gtcttaacat 100

 tagacaaaaa gtaaccttcc tgaagaggac atgtgattgg aagttgtcaa 150

 ttgttgaagc attggtaact ccagtctcta acgttttaga aaatcataac 200

 aagcggttct ctaccctgta aaggtgaact actgagttct tcattatgtc 250

 tgatggagat tatgattacc tcatcaagtt tttagctttg ggagactctg 300

 gtgtagggaa gaccagtgta ctttaccaat atacagatgg taaatttaac 350

 tccaaattta tcacaacagt gggcattgat ttcagggaaa aaagagtggt 400

 gtacagagcc agtgggccgg atggagccac tggcagaggc cagagaatcc 450

 acctgcagtt atgggacaca gcagggcagg agaggtttcg tagcttaacg 500

 acagcgttct tcagagatgc tatgggtttt cttctacttt ttgatctgac 550

 aaatgagcaa agtttcctca atgtcagaaa ctggataagc cagctacaga 600

 tgcatgcata ttgtgaaaac ccagatatag tgctgtgtgg aaacaagagt 650

 gatctggagg accagagagt agtgaaagag gaggaagcca tagcactcgc 700

 agagaaatat ggaatcccct actttgaaac tagtgctgcc aatgggacaa 750

 acataagcca agcaattgag atgcttctgg acctgataat gaagcgaatg 800

 gaacggtgtg tggacaagtc ctggattcct gaaggagtgg tgcgatcaaa 850

 tggtcatgcc tctacggatc agttaagtga agaaaaggag aaaggggcat 900

 gtggctgttg agaagtcaag taagtgacat agtagttcag gtggcccatg 950

 cctgggatct tctctatgat tgatacatgg cacagtgaga gattaatggg 1000

 cattgtgtac aaattgcttc tcaccatccc cattagacct acgaataaag 1050

 catccggttc taaaattaat ttgttgcagc tttgtaaata tttctttaag 1100

 attcagcctg agagttagga gaaatatttc agagccaaaa gtgccttata 1150

 caaccttagc ctattatagt aaatcattca aggattcaga attttgcagt 1200

 cacagaagag tgtatttatt atgtagaatg aatgagggta ctgtcacctg 1250

 ccttaatgta ggtaggccca gagtcttaca tttaagatct tacatgcagt 1300

 tataaaaccg ccacagtctt caatccagat ttgaagactc atgccatagg 1350

 tgacattcta aaataccatt aaagccactt aaatgttaaa taagaatata 1400

 catgcacatc agctcaatgt ctttgagtat taattttatg taagcattct 1450

 atttaacatg aatataggac aaatcatggc tatatctata gaccttggat 1500

 aaactggatt gaccaattat acactcacgg tgactttttt attggtggga 1550

 aggggattgg ggtggggcag gctggcttaa tgtaatatga gcaaccaaag 1600

 tgggacttct gtctccccgc tatattccca ttgctctgaa tggttgattg 1650

 aagggtcagg gaactagatt ttatggcttt agttcactgt gattgtacat 1700

 ttatacttgg cctatgtgct ggccgcacct gaacatagct ggtgcttatg 1750

 ccgagttatt tgtgatgagt aaatatttag tttctttttc ttcatattta 1800

 taatgttgat ctggcatcct caggctgcag ctttattagc ttataaatta 1850

 ctcatctctg tctttaccag caggctctgt attgttgata tttgcaactt 1900

 gttttgcttt tccattggtg gaattgaaat aattagtttt taattacata 1950

 agatgcctgt ttgctatttg gtggaagata gatgttcata ttgaagcagt 2000

 cacatttgta ctgtagttca ataaaagaaa aatgaagtat tctgtagcct 2050

 atatttttca tagagctcat gagcatttac tgtacttgct gggtcttgcc 2100

 aagatcattt attccgctgc attgccaaag tgtcttcata ccaaattaaa 2150

 ggtggtttta atatatgttt catggaagtt gtttataaaa ttcaaaggta 2200

 tttcatttag gtgaaaagtc ttatttatta aagtggtttg aataaagtag 2250

 atcaaaactt ccagagatct taatggctat ataggaagaa atatcactca 2300

 ccataattta aataaagaat aaaaatacat gtattttatg gtggcaaatg 2350

 tttggtagaa ctgtaattag aaaaatacaa gtatatttgc gtgatggtta 2400

 cactagaagc ccagacttta cgactacaca atatattcat gtatctaaac 2450

 tgtacttgta ccccctaaat ttatttttaa aaaaaaaaaa aaaaaa 2496

<210> 2031
<211> 221
<212> PRT
<213> Homo sapien

<400> 2031
 Met Ser Asp Gly Asp Tyr Asp Tyr Leu Ile Lys Phe Leu Ala Leu
   1               5                  10                  15

 Gly Asp Ser Gly Val Gly Lys Thr Ser Val Leu Tyr Gln Tyr Thr
                  20                  25                  30

 Asp Gly Lys Phe Asn Ser Lys Phe Ile Thr Thr Val Gly Ile Asp
                  35                  40                  45

 Phe Arg Glu Lys Arg Val Val Tyr Arg Ala Ser Gly Pro Asp Gly
                  50                  55                  60

 Ala Thr Gly Arg Gly Gln Arg Ile His Leu Gln Leu Trp Asp Thr
                  65                  70                  75

 Ala Gly Gln Glu Arg Phe Arg Ser Leu Thr Thr Ala Phe Phe Arg
                  80                  85                  90

 Asp Ala Met Gly Phe Leu Leu Leu Phe Asp Leu Thr Asn Glu Gln
                  95                 100                 105

 Ser Phe Leu Asn Val Arg Asn Trp Ile Ser Gln Leu Gln Met His
                 110                 115                 120

 Ala Tyr Cys Glu Asn Pro Asp Ile Val Leu Cys Gly Asn Lys Ser
                 125                 130                 135

 Asp Leu Glu Asp Gln Arg Val Val Lys Glu Glu Glu Ala Ile Ala
                 140                 145                 150

 Leu Ala Glu Lys Tyr Gly Ile Pro Tyr Phe Glu Thr Ser Ala Ala
                 155                 160                 165

 Asn Gly Thr Asn Ile Ser Gln Ala Ile Glu Met Leu Leu Asp Leu
                 170                 175                 180

 Ile Met Lys Arg Met Glu Arg Cys Val Asp Lys Ser Trp Ile Pro
                 185                 190                 195

 Glu Gly Val Val Arg Ser Asn Gly His Ala Ser Thr Asp Gln Leu
                 200                 205                 210

 Ser Glu Glu Lys Glu Lys Gly Ala Cys Gly Cys
                 215                 220

<210> 2032
<211> 4336
<212> DNA
<213> Homo sapien

<400> 2032
 gtctaaaact ctcttttctc ttggctcttc ttattcgagt gatgaggagg 50

 aggagttgca taattcacgg cccttccaca gtaccttcca caataccagt 100

 gctaatctga ctgagagtat aacagaagag aactataatt tcctgccaca 150

 tagcccctcc aagaaagatt ctgaatggaa gagtggaaca aaagtcagtc 200

 gtacattcag ctacatcaag aataaaatgt ctagcagcaa gaagagcaaa 250

 gaaaaggaaa aagaaaaaga taagattaag gagaaggaga aagattctaa 300

 agacaaggag aaagataaga agactgtcaa cgggcacact ttcagttcca 350

 ttcctgttgt gggtcccatc agctgtagcc agtgtatgaa gcccttcacc 400

 aacaaagatg cctatacttg tgcaaattgc agtgcttttg tccacaaagg 450

 ctgccgagaa agtctagcct cctgtgcaaa ggtcaaaatg aagcagccca 500

 aagggagcct tcaggcacat gacacatcat cactgcccac ggtcattatg 550

 agaaacaagc cctcacagcc caaggagcgt cctcggtccg cagtcctcct 600

 ggtggatgaa accgctacca ccccaatatt tgccaataga cgatcccagc 650

 agagtgtctc gctctccaaa agtgtctcca tacagaacat tactggagtt 700

 ggcaatgatg agaacatgtc aaacacctgg aaattcctgt ctcattcaac 750

 agactcacta aataaaatca gcaaggtcaa tgagtcaaca gaatcactta 800

 ctgatgaggg agtaggtaca gacatgaatg aaggacaact actgggagac 850

 tttgagattg agtccaaaca gctggaagca gagtcttgga gtcggataat 900

 agacagcaag tttctaaaac agcaaaagaa agatgtggtc aaacggcaag 950

 aagtaatata tgagttgatg cagacagagt ttcatcatgt ccgcactctc 1000

 aagatcatga gtggtgtgta cagccagggg atgatggcgg atctgctttt 1050

 tgagcagcag atggtagaaa agctgttccc ctgtttggat gagctgatca 1100

 gtatccatag ccaattcttc cagaggattc tggagcggaa gaaggagtct 1150

 ctggtggata aaagtgaaaa gaactttctc atcaagagga taggggatgt 1200

 gcttgtaaat cagttttcag gtgagaatgc agaacgttta aagaagacat 1250

 atggcaagtt ttgtgggcaa cataaccagt ctgtaaacta cttcaaagac 1300

 ctttatgcca aggataagcg ttttcaagcc tttgtaaaga agaagatgag 1350

 cagttcagtt gttagaaggc ttggaattcc agagtgcata ttgcttgtaa 1400

 ctcagcggat taccaagtac ccagttttat tccaaagaat attgcagtgt 1450

 accaaagaca atgaagtgga gcaggaagat ctagcacagt ccttgagcct 1500

 ggtgaaggat gtgattggag ctgtagacag caaagtggca agttatgaaa 1550

 agaaagtgcg tctcaatgag atttatacaa agacagatag caagtcaatc 1600

 atgaggatga agagtggtca gatgtttgcc aaggaagatt tgaaacggaa 1650

 gaagcttgta cgtgatggga gtgtgtttct gaagaatgca gcaggaaggt 1700

 tgaaagaggt tcaagcagtt cttctcactg acattttagt tttccttcaa 1750

 gaaaaagacc agaagtacat ctttgcatca ttggaccaga agtcaacagt 1800

 gatctcttta aagaagctga ttgtgagaga agtggcacat gaggagaaag 1850

 gtttattcct gatcagcatg gggatgacag atccagagat ggtagaagtc 1900

 catgccagct ccaaagagga acgaaacagc tggattcaga tcattcagga 1950

 cacaatcaac accctgaaca gagatgaaga tgaaggaatt cctagtgaga 2000

 atgaggaaga aaagaaaatg ttggacacca gagcccgaga attaaaagaa 2050

 caacttcacc agaaggacca aaaaatccta ctcttgttgg aagagaagga 2100

 gatgattttc cgggacatgg ctgagtgcag cacccctctc ccagaggatt 2150

 gctccccaac acatagccct agagttctct tccgctccaa cacagaagag 2200

 gctctcaaag gaggaccttt aatgaaaagt gcaataaatg aggtggagat 2250

 ccttcagggt ttggtgagtg gaaatctggg aggcacactt gggccgactg 2300

 tcagcagccc cattgagcaa gatgtggtcg gtcccgtttc cctgccccgg 2350

 agagcagaga cctttggagg atttgacagc catcagatga atgcttcaaa 2400

 aggaggcgag aaggaagagg gagatgatgg ccaagatctt aggagaacgg 2450

 aatcagatag tggcctaaaa aagggtggaa atgctaacct ggtatttatg 2500

 cttaaaagaa acagtgagca ggttgtccag agcgttgttc atctctacga 2550

 gctcctcagc gctctgcagg gtgtggtgct gcagcaggac agctacattg 2600

 aggaccagaa actggtgctg agcgagaggg cgctcactcg cagcttgtcc 2650

 cgcccgagct ccctcattga gcaggagaag cagcgcagcc tggagaagca 2700

 gcgccaggac ctggccaacc tgcagaagca gcaggcccag tacctcgagg 2750

 agaagcgcag gcgcgagcgt gagtgggaag ctcgtgagag ggagctgcgg 2800

 gagcgggagg ccctcctggc ccagcgcgag gaggaggtgc agcaggggca 2850

 gcaggacctg gaaaaggagc gggaggagct ccagcagaag aagggcacat 2900

 accagtatga cctggagcga ctgcgtgctg cccagaaaca gcttgagagg 2950

 gaacaggagc agctgcgccg ggaggcagag cggctcagcc agcggcagac 3000

 agaacgggac ctgtgtcagg tttcccatcc acataccaag ctgatgagga 3050

 tcccatcgtt cttccccagt cctgaggagc ccccctcgcc atctgcacct 3100

 tccatagcca aatcagggtc attggactca gaactttcag tgtccccaaa 3150

 aaggaacagc atctctcgga cacacaaaga taaggggcct tttcacatac 3200

 tgagttcaac cagccagaca aacaaaggac cagaagggca gagccaggcc 3250

 cctgcgtcca cctctgcctc tacccgcctg tttgggttaa caaagccaaa 3300

 ggaaaagaag gagaaaaaaa agaagaacaa aaccagccgc tctcagcccg 3350

 gtgatggtcc cgcgtcagaa gtatcagcag agggtgaaga gatcttctgc 3400

 tgaccctctt cctctctgct gaggcagctg cctcctgatc ctggccagcc 3450

 cacctctcct gctgtccccg cgtgcacaag tctcttacac tggacgccca 3500

 ctgctcctca gcgtccagtc ctcctgggcg gccccaggtc ctggacaata 3550

 agcaacagat gatattgagt gtcgggtggg gaaggaggcc cagactctgc 3600

 ttcggccatg atttgtgact gcccaggact ctcaggttgg gctggcccta 3650

 ctcaggatta cactgaaagt aatggcctcg taagtacagg tgatggtttt 3700

 ggacacgtca ggaattccta aaggctgaaa gagtgtatcc aagtaaggtc 3750

 tgaacctccg actgcctttt atttggggga acacaaaacc aaacagcaga 3800

 tgttttggac ttgatctgtg tacgtacatg gggacctgtc tgcatataca 3850

 cacggggaat gccagaagaa ggcccagtct gcaccaggcg tctggtcaac 3900

 ttagcacaag ggcagtgcct ggacggaccc ggagcccccg catatcagca 3950

 gttcacccag tactcctcag agactggttt ccctctaaac ccatcccggg 4000

 cacataccac ccctgttttg catgtatttc tcatttcatt ttagggatga 4050

 caaacatttg tgaaaccagt gagagaaggc ttgatgtgta taaaagacgt 4100

 gatgtgcacc acctcgatct cggtgtttca ggcactaaag caacaaaaca 4150

 acccatagta tctcattttg tcatcagatc cagaagaaat atcctggttt 4200

 tccagcatgt ttacccacat gttttgggca tggataaagt gaagagggct 4250

 actcaccatt atccctgcag cgtgacacct tttgattgtc actgaccact 4300

 cagaaggggc cacggcctcc tggctgtgtt cctgag 4336

<210> 2033
<211> 1058
<212> PRT
<213> Homo sapien

<400> 2033
 Met Ser Ser Ser Lys Lys Ser Lys Glu Lys Glu Lys Glu Lys Asp
   1               5                  10                  15

 Lys Ile Lys Glu Lys Glu Lys Asp Ser Lys Asp Lys Glu Lys Asp
                  20                  25                  30

 Lys Lys Thr Val Asn Gly His Thr Phe Ser Ser Ile Pro Val Val
                  35                  40                  45

 Gly Pro Ile Ser Cys Ser Gln Cys Met Lys Pro Phe Thr Asn Lys
                  50                  55                  60

 Asp Ala Tyr Thr Cys Ala Asn Cys Ser Ala Phe Val His Lys Gly
                  65                  70                  75

 Cys Arg Glu Ser Leu Ala Ser Cys Ala Lys Val Lys Met Lys Gln
                  80                  85                  90

 Pro Lys Gly Ser Leu Gln Ala His Asp Thr Ser Ser Leu Pro Thr
                  95                 100                 105

 Val Ile Met Arg Asn Lys Pro Ser Gln Pro Lys Glu Arg Pro Arg
                 110                 115                 120

 Ser Ala Val Leu Leu Val Asp Glu Thr Ala Thr Thr Pro Ile Phe
                 125                 130                 135

 Ala Asn Arg Arg Ser Gln Gln Ser Val Ser Leu Ser Lys Ser Val
                 140                 145                 150

 Ser Ile Gln Asn Ile Thr Gly Val Gly Asn Asp Glu Asn Met Ser
                 155                 160                 165

 Asn Thr Trp Lys Phe Leu Ser His Ser Thr Asp Ser Leu Asn Lys
                 170                 175                 180

 Ile Ser Lys Val Asn Glu Ser Thr Glu Ser Leu Thr Asp Glu Gly
                 185                 190                 195

 Val Gly Thr Asp Met Asn Glu Gly Gln Leu Leu Gly Asp Phe Glu
                 200                 205                 210

 Ile Glu Ser Lys Gln Leu Glu Ala Glu Ser Trp Ser Arg Ile Ile
                 215                 220                 225

 Asp Ser Lys Phe Leu Lys Gln Gln Lys Lys Asp Val Val Lys Arg
                 230                 235                 240

 Gln Glu Val Ile Tyr Glu Leu Met Gln Thr Glu Phe His His Val
                 245                 250                 255

 Arg Thr Leu Lys Ile Met Ser Gly Val Tyr Ser Gln Gly Met Met
                 260                 265                 270

 Ala Asp Leu Leu Phe Glu Gln Gln Met Val Glu Lys Leu Phe Pro
                 275                 280                 285

 Cys Leu Asp Glu Leu Ile Ser Ile His Ser Gln Phe Phe Gln Arg
                 290                 295                 300

 Ile Leu Glu Arg Lys Lys Glu Ser Leu Val Asp Lys Ser Glu Lys
                 305                 310                 315

 Asn Phe Leu Ile Lys Arg Ile Gly Asp Val Leu Val Asn Gln Phe
                 320                 325                 330

 Ser Gly Glu Asn Ala Glu Arg Leu Lys Lys Thr Tyr Gly Lys Phe
                 335                 340                 345

 Cys Gly Gln His Asn Gln Ser Val Asn Tyr Phe Lys Asp Leu Tyr
                 350                 355                 360

 Ala Lys Asp Lys Arg Phe Gln Ala Phe Val Lys Lys Lys Met Ser
                 365                 370                 375

 Ser Ser Val Val Arg Arg Leu Gly Ile Pro Glu Cys Ile Leu Leu
                 380                 385                 390

 Val Thr Gln Arg Ile Thr Lys Tyr Pro Val Leu Phe Gln Arg Ile
                 395                 400                 405

 Leu Gln Cys Thr Lys Asp Asn Glu Val Glu Gln Glu Asp Leu Ala
                 410                 415                 420

 Gln Ser Leu Ser Leu Val Lys Asp Val Ile Gly Ala Val Asp Ser
                 425                 430                 435

 Lys Val Ala Ser Tyr Glu Lys Lys Val Arg Leu Asn Glu Ile Tyr
                 440                 445                 450

 Thr Lys Thr Asp Ser Lys Ser Ile Met Arg Met Lys Ser Gly Gln
                 455                 460                 465

 Met Phe Ala Lys Glu Asp Leu Lys Arg Lys Lys Leu Val Arg Asp
                 470                 475                 480

 Gly Ser Val Phe Leu Lys Asn Ala Ala Gly Arg Leu Lys Glu Val
                 485                 490                 495

 Gln Ala Val Leu Leu Thr Asp Ile Leu Val Phe Leu Gln Glu Lys
                 500                 505                 510

 Asp Gln Lys Tyr Ile Phe Ala Ser Leu Asp Gln Lys Ser Thr Val
                 515                 520                 525

 Ile Ser Leu Lys Lys Leu Ile Val Arg Glu Val Ala His Glu Glu
                 530                 535                 540

 Lys Gly Leu Phe Leu Ile Ser Met Gly Met Thr Asp Pro Glu Met
                 545                 550                 555

 Val Glu Val His Ala Ser Ser Lys Glu Glu Arg Asn Ser Trp Ile
                 560                 565                 570

 Gln Ile Ile Gln Asp Thr Ile Asn Thr Leu Asn Arg Asp Glu Asp
                 575                 580                 585

 Glu Gly Ile Pro Ser Glu Asn Glu Glu Glu Lys Lys Met Leu Asp
                 590                 595                 600

 Thr Arg Ala Arg Glu Leu Lys Glu Gln Leu His Gln Lys Asp Gln
                 605                 610                 615

 Lys Ile Leu Leu Leu Leu Glu Glu Lys Glu Met Ile Phe Arg Asp
                 620                 625                 630

 Met Ala Glu Cys Ser Thr Pro Leu Pro Glu Asp Cys Ser Pro Thr
                 635                 640                 645

 His Ser Pro Arg Val Leu Phe Arg Ser Asn Thr Glu Glu Ala Leu
                 650                 655                 660

 Lys Gly Gly Pro Leu Met Lys Ser Ala Ile Asn Glu Val Glu Ile
                 665                 670                 675

 Leu Gln Gly Leu Val Ser Gly Asn Leu Gly Gly Thr Leu Gly Pro
                 680                 685                 690

 Thr Val Ser Ser Pro Ile Glu Gln Asp Val Val Gly Pro Val Ser
                 695                 700                 705

 Leu Pro Arg Arg Ala Glu Thr Phe Gly Gly Phe Asp Ser His Gln
                 710                 715                 720

 Met Asn Ala Ser Lys Gly Gly Glu Lys Glu Glu Gly Asp Asp Gly
                 725                 730                 735

 Gln Asp Leu Arg Arg Thr Glu Ser Asp Ser Gly Leu Lys Lys Gly
                 740                 745                 750

 Gly Asn Ala Asn Leu Val Phe Met Leu Lys Arg Asn Ser Glu Gln
                 755                 760                 765

 Val Val Gln Ser Val Val His Leu Tyr Glu Leu Leu Ser Ala Leu
                 770                 775                 780

 Gln Gly Val Val Leu Gln Gln Asp Ser Tyr Ile Glu Asp Gln Lys
                 785                 790                 795

 Leu Val Leu Ser Glu Arg Ala Leu Thr Arg Ser Leu Ser Arg Pro
                 800                 805                 810

 Ser Ser Leu Ile Glu Gln Glu Lys Gln Arg Ser Leu Glu Lys Gln
                 815                 820                 825

 Arg Gln Asp Leu Ala Asn Leu Gln Lys Gln Gln Ala Gln Tyr Leu
                 830                 835                 840

 Glu Glu Lys Arg Arg Arg Glu Arg Glu Trp Glu Ala Arg Glu Arg
                 845                 850                 855

 Glu Leu Arg Glu Arg Glu Ala Leu Leu Ala Gln Arg Glu Glu Glu
                 860                 865                 870

 Val Gln Gln Gly Gln Gln Asp Leu Glu Lys Glu Arg Glu Glu Leu
                 875                 880                 885

 Gln Gln Lys Lys Gly Thr Tyr Gln Tyr Asp Leu Glu Arg Leu Arg
                 890                 895                 900

 Ala Ala Gln Lys Gln Leu Glu Arg Glu Gln Glu Gln Leu Arg Arg
                 905                 910                 915

 Glu Ala Glu Arg Leu Ser Gln Arg Gln Thr Glu Arg Asp Leu Cys
                 920                 925                 930

 Gln Val Ser His Pro His Thr Lys Leu Met Arg Ile Pro Ser Phe
                 935                 940                 945

 Phe Pro Ser Pro Glu Glu Pro Pro Ser Pro Ser Ala Pro Ser Ile
                 950                 955                 960

 Ala Lys Ser Gly Ser Leu Asp Ser Glu Leu Ser Val Ser Pro Lys
                 965                 970                 975

 Arg Asn Ser Ile Ser Arg Thr His Lys Asp Lys Gly Pro Phe His
                 980                 985                 990

 Ile Leu Ser Ser Thr Ser Gln Thr Asn Lys Gly Pro Glu Gly Gln
                 995                1000                1005

 Ser Gln Ala Pro Ala Ser Thr Ser Ala Ser Thr Arg Leu Phe Gly
                1010                1015                1020

 Leu Thr Lys Pro Lys Glu Lys Lys Glu Lys Lys Lys Lys Asn Lys
                1025                1030                1035

 Thr Ser Arg Ser Gln Pro Gly Asp Gly Pro Ala Ser Glu Val Ser
                1040                1045                1050

 Ala Glu Gly Glu Glu Ile Phe Cys
                1055

<210> 2034
<211> 2950
<212> DNA
<213> Homo sapien

<400> 2034
 ggcacgaggg agagtcgaac ccggagcagg gtcccatccg agcgtggact 50

 ggcggcagga tgttcagctg gatggggcgg caggcgggcg ggcgcgaacg 100

 cgctggcggc gcggacgcgg tgcagacggt gacgggcggg ctgcgctcgc 150

 tctacctgcg caaggtgctg ccgctggagg aggcgtaccg cttccacgag 200

 ttccactcgc ctgcgctgga ggacgccgac ttcgagaaca agcccatgat 250

 cctgctggtg ggccagtaca gcaccggcaa gaccaccttc atcagatacc 300

 tactggagca ggatttccca ggcatgagga ttggtccgga gcccaccaca 350

 gactccttca tcgccgtgat gtatggagag actgagggca gcaccccagg 400

 gaatgcttta gtcgtggacc ccaaaaagcc gtttagaaag ctcagtcgct 450

 ttggaaacgc tttcctgaat cgattcatgt gctcacagct ccccaatcag 500

 gtcctgaaga gcatcagcgt catcgacagc cccggcatcc tttctgggga 550

 gaagcagcgc atcagccgag gctatgactt ctgccaggtc ctgcagtggt 600

 ttgccgagag ggtggacagg atcatcctgc tctttgacgc tcacaagctg 650

 gacatctcag atgaattctc agaggccatc aaggccttcc ggggccagga 700

 cgacaagatc cgtgtcgtgc tgaataaggc cgaccaagtg gacacgcagc 750

 agctgatgcg ggtctacggg gccctcatgt ggtccctagg caaggtcatc 800

 aacacgcccg aggtactgcg cgtctacatt ggctccttct gggcgcagcc 850

 cctgcagaac acggacaacc gccggctctt cgaggctgag gcccaggacc 900

 tcttcagaga catccagagc ctcccccaga aggcagcggt gcgcaagctc 950

 aacgacctca tcaagcgagc gaggctggcc aaggtgcatg cctacatcat 1000

 cagctacctg aagaaggaga tgccaagtgt atttggaaag gaaaacaaga 1050

 agagagagct tatcagcagg ctaccggaaa tctacattca gctacagcga 1100

 gaataccaga tttctgcagg ggacttccct gaggtcaagg ctatgcagga 1150

 acagcttgag aactatgact tcaccaaatt ccactcgctg aagcccaagc 1200

 tgatcgaggc agtggacaac atgctgagca acaagatctc gcccctcatg 1250

 aacctcatca gccaggagga gacgagcacg cccacgcagc tggtgcaggg 1300

 cggcgccttc gatggcacca ccgagggccc cttcaaccag ggctacgggg 1350

 agggtgccaa ggagggcgcc gacgaggagg agtgggtcgt ggccaaagac 1400

 aagcccgtct acgacgagct cttctacact ctgtcgccca tcaatggcaa 1450

 gatatcaggt gtcaacgcca agaaggagat ggtgacctcc aagctgccca 1500

 acagcgtcct gggcaagatc tggaagctgg ccgactgcga ctgcgacggc 1550

 atgcttgatg aggaggagtt cgcgctggcc aagcacctca tcaagatcaa 1600

 gctcgacggc tacgagctgc ccagcagcct gcccccccac ctcgtgcccc 1650

 cctcgcacag gaagtccctg cccaaggccg actgaggggt gggctgcaga 1700

 acggggtggg aactggggga cctgggcctc aggcctgctc caccactgac 1750

 tcaccgaatg accttgggca aggcactgcc ctctctgtgc cttggtttcc 1800

 ccatctgtag aatggggagg gtggacactg gaaactagat gacttctttc 1850

 acctccaaaa ttcccttagt ttctatgaaa atattggggg taggggggtg 1900

 gattaggaga ttgaagggtt gagaagaaag agaaattgtc caaagagtcc 1950

 tcagaacctg cctggagaaa tgcgcatggg ggtgggcctg gtaagtccca 2000

 ggaaccacag gaagtgagct aaggctcacc cagagcagct gggtctccag 2050

 gctgcctggg ctttttgtcc tcatgaacaa ctctggagca gctgtctgtc 2100

 cctcagaggg cacctggagg cagcaaagat tatcttattt attttatttt 2150

 gttttctgct atatttagag tggcaaaaaa atagagcaga gggtttctgc 2200

 tgtctccaga ctgtctacca aagagaaggc gacagatgcc tcctgggttt 2250

 ggaaggggga tgcactgtgg atctgccatc cattctgcag tctccagcag 2300

 agcaggcagt caggccccag cgtgcctcca tcccagtgcc ccgatgacca 2350

 tctggtcagc cctcccaacc tcccttccag ggggcttacc agcaaagcca 2400

 tattcggcta ggaatttgga attcacaacc tttattaacc cctggcaaaa 2450

 cttcccgttt gcatgtcaaa tcacattgaa gcctgaagat tagcttttct 2500

 tactggtttt tccaataagt aatagcaaag cccacttatc atacttaaac 2550

 tacagtaaag aaaagaggtg gttctctgca gtgatcgttt agtgtggccc 2600

 tcaaacatta aatatcccca ggtctccttg gtgggtggca ggatttaaat 2650

 tcaatcaaat cctgtcctag tgtgtgcagt gtcttcggcc ctgtggacac 2700

 aggtgaatga gggaccagcc ctgccctggg ctgttgagaa gagatcagtc 2750

 cacccagagt tagacattgt ttttgtagaa aacaggcatt tattatgtct 2800

 agggttttgt gttttttttt tttccttaca ggataaaagc ctttatacag 2850

 aaacaaaatg gaacctttca tataaaacct tttctttaaa aaaaaaaaaa 2900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2950

<210> 2035
<211> 541
<212> PRT
<213> Homo sapien

<400> 2035
 Met Phe Ser Trp Met Gly Arg Gln Ala Gly Gly Arg Glu Arg Ala
   1               5                  10                  15

 Gly Gly Ala Asp Ala Val Gln Thr Val Thr Gly Gly Leu Arg Ser
                  20                  25                  30

 Leu Tyr Leu Arg Lys Val Leu Pro Leu Glu Glu Ala Tyr Arg Phe
                  35                  40                  45

 His Glu Phe His Ser Pro Ala Leu Glu Asp Ala Asp Phe Glu Asn
                  50                  55                  60

 Lys Pro Met Ile Leu Leu Val Gly Gln Tyr Ser Thr Gly Lys Thr
                  65                  70                  75

 Thr Phe Ile Arg Tyr Leu Leu Glu Gln Asp Phe Pro Gly Met Arg
                  80                  85                  90

 Ile Gly Pro Glu Pro Thr Thr Asp Ser Phe Ile Ala Val Met Tyr
                  95                 100                 105

 Gly Glu Thr Glu Gly Ser Thr Pro Gly Asn Ala Leu Val Val Asp
                 110                 115                 120

 Pro Lys Lys Pro Phe Arg Lys Leu Ser Arg Phe Gly Asn Ala Phe
                 125                 130                 135

 Leu Asn Arg Phe Met Cys Ser Gln Leu Pro Asn Gln Val Leu Lys
                 140                 145                 150

 Ser Ile Ser Val Ile Asp Ser Pro Gly Ile Leu Ser Gly Glu Lys
                 155                 160                 165

 Gln Arg Ile Ser Arg Gly Tyr Asp Phe Cys Gln Val Leu Gln Trp
                 170                 175                 180

 Phe Ala Glu Arg Val Asp Arg Ile Ile Leu Leu Phe Asp Ala His
                 185                 190                 195

 Lys Leu Asp Ile Ser Asp Glu Phe Ser Glu Ala Ile Lys Ala Phe
                 200                 205                 210

 Arg Gly Gln Asp Asp Lys Ile Arg Val Val Leu Asn Lys Ala Asp
                 215                 220                 225

 Gln Val Asp Thr Gln Gln Leu Met Arg Val Tyr Gly Ala Leu Met
                 230                 235                 240

 Trp Ser Leu Gly Lys Val Ile Asn Thr Pro Glu Val Leu Arg Val
                 245                 250                 255

 Tyr Ile Gly Ser Phe Trp Ala Gln Pro Leu Gln Asn Thr Asp Asn
                 260                 265                 270

 Arg Arg Leu Phe Glu Ala Glu Ala Gln Asp Leu Phe Arg Asp Ile
                 275                 280                 285

 Gln Ser Leu Pro Gln Lys Ala Ala Val Arg Lys Leu Asn Asp Leu
                 290                 295                 300

 Ile Lys Arg Ala Arg Leu Ala Lys Val His Ala Tyr Ile Ile Ser
                 305                 310                 315

 Tyr Leu Lys Lys Glu Met Pro Ser Val Phe Gly Lys Glu Asn Lys
                 320                 325                 330

 Lys Arg Glu Leu Ile Ser Arg Leu Pro Glu Ile Tyr Ile Gln Leu
                 335                 340                 345

 Gln Arg Glu Tyr Gln Ile Ser Ala Gly Asp Phe Pro Glu Val Lys
                 350                 355                 360

 Ala Met Gln Glu Gln Leu Glu Asn Tyr Asp Phe Thr Lys Phe His
                 365                 370                 375

 Ser Leu Lys Pro Lys Leu Ile Glu Ala Val Asp Asn Met Leu Ser
                 380                 385                 390

 Asn Lys Ile Ser Pro Leu Met Asn Leu Ile Ser Gln Glu Glu Thr
                 395                 400                 405

 Ser Thr Pro Thr Gln Leu Val Gln Gly Gly Ala Phe Asp Gly Thr
                 410                 415                 420

 Thr Glu Gly Pro Phe Asn Gln Gly Tyr Gly Glu Gly Ala Lys Glu
                 425                 430                 435

 Gly Ala Asp Glu Glu Glu Trp Val Val Ala Lys Asp Lys Pro Val
                 440                 445                 450

 Tyr Asp Glu Leu Phe Tyr Thr Leu Ser Pro Ile Asn Gly Lys Ile
                 455                 460                 465

 Ser Gly Val Asn Ala Lys Lys Glu Met Val Thr Ser Lys Leu Pro
                 470                 475                 480

 Asn Ser Val Leu Gly Lys Ile Trp Lys Leu Ala Asp Cys Asp Cys
                 485                 490                 495

 Asp Gly Met Leu Asp Glu Glu Glu Phe Ala Leu Ala Lys His Leu
                 500                 505                 510

 Ile Lys Ile Lys Leu Asp Gly Tyr Glu Leu Pro Ser Ser Leu Pro
                 515                 520                 525

 Pro His Leu Val Pro Pro Ser His Arg Lys Ser Leu Pro Lys Ala
                 530                 535                 540

 Asp


<210> 2036
<211> 1140
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 23
<223> Unknown base

<400> 2036
 ctggcgctgc tggggctcgg cgncggcctt tgtctgcggg cacggccgct 50

 gcggtgctca ggaacagccc atggaagaat catatgaaga ggtggtgact 100

 gaggtcgtaa gcaggagtgg acatgtttgg atttccaaca gctaccctgc 150

 tggactgtca tggaagatat gcccagaatg tagcgttctt caatgtgatg 200

 actgaagccc accacaaata tgaccactct gaggctacag gatcctcaag 250

 ctgggatatc caaaattctt tcagaagaga gaagctggaa caaaaatccc 300

 cagattcgaa gacactacag gaagattcac ctggagtgag acaaagggtc 350

 tatgagtgcc aggagtgtgg aaaatccttc cggcaaaaag gtagtctaac 400

 gttacatgag agaatccaca ctggtcaaaa gccttttgag tgcacccact 450

 gtggaaaaag cttcagggcc aaaggcaatc ttgttacaca tcaacggata 500

 cacacgggag agaagcctta tcagtgcaag gagtgtggga aaagcttcag 550

 tcaacgaggt agtctcgctg tccacgagag actccacact ggacagaaac 600

 cctacgagtg tgctatttgt cagagaagct tcaggaatca gagtaacctt 650

 gctgttcaca ggagagttca cagtggtgag aagccctata gatgtgatca 700

 gtgtggaaaa gccttcagtc agaaaggaag cttaattgtt cacatcagag 750

 tccacacagg cctgaagccc tatgcctgta cccagtgcag gaagagtttc 800

 cacaccaggg ggaattgtat tctgcatggc aaaatccaca caggagagac 850

 accctatctg tgcggccagt gtggaaaaag cttcacccag agagggagtc 900

 tggctgtgca ccagcgaagc tgctcacaga ggctcaccct ttgaccactt 950

 tcctgaagag aagttctctt tatgaattaa gagtacaaaa tcctctgaga 1000

 tgaagcaacc tatccagttc tatggaatga atggagaatc tttcagaaag 1050

 accatcattg ggtagggcaa actgattttt ttcctttccc ccaaaagagt 1100

 atgaaaaata aaggtcttgt ttattatcat taaaaaaaaa 1140

<210> 2037
<211> 273
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 23
<223> Unknown amino acid

<400> 2037
 Met Phe Gly Phe Pro Thr Ala Thr Leu Leu Asp Cys His Gly Arg
   1               5                  10                  15

 Tyr Ala Gln Asn Val Ala Phe Phe Asn Val Met Thr Glu Ala His
                  20                  25                  30

 His Lys Tyr Asp His Ser Glu Ala Thr Gly Ser Ser Ser Trp Asp
                  35                  40                  45

 Ile Gln Asn Ser Phe Arg Arg Glu Lys Leu Glu Gln Lys Ser Pro
                  50                  55                  60

 Asp Ser Lys Thr Leu Gln Glu Asp Ser Pro Gly Val Arg Gln Arg
                  65                  70                  75

 Val Tyr Glu Cys Gln Glu Cys Gly Lys Ser Phe Arg Gln Lys Gly
                  80                  85                  90

 Ser Leu Thr Leu His Glu Arg Ile His Thr Gly Gln Lys Pro Phe
                  95                 100                 105

 Glu Cys Thr His Cys Gly Lys Ser Phe Arg Ala Lys Gly Asn Leu
                 110                 115                 120

 Val Thr His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr Gln Cys
                 125                 130                 135

 Lys Glu Cys Gly Lys Ser Phe Ser Gln Arg Gly Ser Leu Ala Val
                 140                 145                 150

 His Glu Arg Leu His Thr Gly Gln Lys Pro Tyr Glu Cys Ala Ile
                 155                 160                 165

 Cys Gln Arg Ser Phe Arg Asn Gln Ser Asn Leu Ala Val His Arg
                 170                 175                 180

 Arg Val His Ser Gly Glu Lys Pro Tyr Arg Cys Asp Gln Cys Gly
                 185                 190                 195

 Lys Ala Phe Ser Gln Lys Gly Ser Leu Ile Val His Ile Arg Val
                 200                 205                 210

 His Thr Gly Leu Lys Pro Tyr Ala Cys Thr Gln Cys Arg Lys Ser
                 215                 220                 225

 Phe His Thr Arg Gly Asn Cys Ile Leu His Gly Lys Ile His Thr
                 230                 235                 240

 Gly Glu Thr Pro Tyr Leu Cys Gly Gln Cys Gly Lys Ser Phe Thr
                 245                 250                 255

 Gln Arg Gly Ser Leu Ala Val His Gln Arg Ser Cys Ser Gln Arg
                 260                 265                 270

 Leu Thr Leu


<210> 2038
<211> 4839
<212> DNA
<213> Homo sapien

<400> 2038
 ggctgtttgg agtgtaccgt cctcagtaat gaatccagaa gaacaaatcg 50

 tgacatggct tatatctttg ggagttttag agtcccctaa aaagaccatc 100

 tgtgatccgg aggagttttt aaagtcctcg ctgaaaaatg gggtagttct 150

 gtgcaaactg atcaacagac tcatgcctgg ctctgtggaa aagttttgtc 200

 tggatcccca aactgaagct gactgcatca acaacatcaa tgacttcctg 250

 aaaggatgtg caaccctcca agtggaaata tttgatcctg atgaccttta 300

 ttcaggggtc aatttctcca aggtactgag tactctttta gctgtcaaca 350

 aagcaacaga agatcagcta tcagaaagac catgtggacg ttcctcttct 400

 cttagtgctg ctaatacttc tcagacaaac ccacagggag cagtttctag 450

 cacagtttca gggctgcaaa ggcagtcaaa gacagtggag atgacggaaa 500

 atggaagtca tcagttgata gtaaaagcaa gattcaactt taagcagact 550

 aatgaggatg aactgtcagt ttgtaagggg gacatcattt acgtcacacg 600

 agttgaagaa ggaggctggt gggaaggcac attaaatggg agaacaggct 650

 ggttccccag taattatgtc cgtgaaatta aatccagtga gagacctctc 700

 tccccaaaag ccgtcaaagg atttgaaact gctccactta ccaagaatta 750

 ttatactgtg gtgttacaga acatcctgga cactgaaaaa gaatatgcta 800

 aagaacttca gtctcttctt gttacttact taagacccct gcagtccaat 850

 aacaatctga gtactgtgga ggttacatct ttactgggaa acttcgagga 900

 agtatgcaca tttcaacaga cactctgcca agccttggaa gaatgttcaa 950

 agtttccaga aaaccagcac aaagtaggag gttgtctact gagtctcatg 1000

 cctcatttta aatctatgta tctggcttac tgtgcaaacc atccttcagc 1050

 tgtaaatgtg ctcactcagc acagtgatga gttggaacaa ttcatggaaa 1100

 atcaaggtgc atcgagccca ggtatcctca ttttaacaac aaacctcagc 1150

 aaaccattca tgcgactgga gaaatatgtt actctcttgc aagagttaga 1200

 acggcatatg gaggatactc atccagatca tcaggatatt ctgaaagcaa 1250

 tcgtagcatt caaaactctc atggggcaat gtcaagatct gaggaagaga 1300

 aaacagctgg agttacagat actgtccgaa cctattcagg catgggaagg 1350

 agaagatatt aaaaacttgg gaaatgtgat ttttatgtca caagtaatgg 1400

 tgcagtatgg agcatgtgag gaaaaagagg agcggtacct tatgttattt 1450

 tcaaatgtcc tgataatgtt atctgcaagt cctcggatga gtggctttat 1500

 ctatcaggga aaaataccaa tagcaggaac ggtggtgact agattagatg 1550

 aaattgaagg gaatgactgc acatttgaaa tcactggtaa cacagtggag 1600

 agaattgtgg tccattgtaa caacaaccag gacttccagg aatggttgga 1650

 gcagctgaac agactgatca gaggacctgc ctcttgcagt tcattatcca 1700

 aaacctcatc gtcatcatgt agtgctcatt cttcttttag ctctaccgga 1750

 cagccccgag gacccttgga gcctcctcaa attataaaac cgtggagttt 1800

 aagttgtcta cgacctgcac ctccacttag accatcagca gcactaggtt 1850

 ataaagagag gatgtcttat atcttaaagg agtctagtaa aagccctaaa 1900

 acgatgaaga aatttcttca taaaaggaag actgagagaa aaccatcgga 1950

 ggaggaatat gtgattagga aaagtacagc tgctctggaa gaggatgctc 2000

 aaatccttaa agtgatcgaa gcctactgca ccagcgcaaa ttttcaacaa 2050

 ggccatggct caagtactcg aaaagattcc attccacaag tcctactccc 2100

 tgaggaagag aaactcatca ttgaagaaac cagaagcaac ggccagacca 2150

 tcatggaaga aaagagcctt gttgatactg tttacgcctt gaaggacgag 2200

 gtcagagaac tgaagcagga aaataaaaga atgaagcaat gcctggaaga 2250

 agaactgaaa tcaagaaggg acctagaaaa gctggtgcgg aggcttttga 2300

 agcaaacaga tgagtgtatt cgaggcgagt ccagtagcaa gacctcaatt 2350

 cttccataac catcactgtg ccactgggtg gagtgtgcct tcagggcatc 2400

 ttgaaatgtc ccgctgaatg atttgactca gtttgctcac ttctttggct 2450

 tttgttttgt gtttgagtct ctctctctct ctccctctct cttctctttc 2500

 tctccccgct gtgtgcatat gtgtgtgcgt gcacgtgcgc gcttgggcat 2550

 ttgctgttgt ttggttattg gttggttgtt catttttttt ttcaacaggt 2600

 gaaaaagcag gaagtggtgg tagagatggc ctcagagtct tttccattca 2650

 gtaagaaaga gaaagggaat gcaggccagt tacttaaaag gtcttcagat 2700

 tgccttcagt tcacagtgcc tctgcaacag ccattgccct caggtcacat 2750

 tctttgggct ggctgccctt gcaaagcagc tggccaaggc ttattaaatg 2800

 tgaacccaac ttttccccag ggctttcctg tacctgcaag cctcttagta 2850

 cttaatttac cgaaggcaaa tcttccagac tatggcttga gtaggatgaa 2900

 agacaaacac atctgcccaa tgatccagct gcccttcctt agaccatcac 2950

 atgcctcccc tcaatcacag gttttaaaat tactgcccta tgttgtctat 3000

 aagaccaaga aaactgtagt acccttattc cttttgtgtc atgtaaattg 3050

 taactcaggg gggcagaagc tctggtcacc cacaccaaca ccaaatccat 3100

 cagcaaattc tactggacaa tcctcccttt tagtagcaga gttgaccgcc 3150

 ttttcccatt gcatgatagg tttctttccc tcattctgcc tagtgtgtaa 3200

 gttttctatt tccccagtac ttttagccaa ccttaccaag tggtgtgtaa 3250

 actagtatgt atgtgctttg cttacttttt aaaaaaatgt agttagactg 3300

 tgaggagtta ctttatgtac gttgcatatt caaactgtga tgttttatcc 3350

 ttcaaaacaa tctgcattaa gaagatattg tgccctacta gacagctttc 3400

 attcacttta ttactctctc atatatgctg tgagaagttg taatattaat 3450

 tggcctcttt gggtgggact ctaagcagta tttgcagaaa tatgcttctg 3500

 gtccaacttg tacatccaga acaaaagggc ccctctagta gctgtgtgct 3550

 ggattattca ggactgatta actcaagttg ctcattgaat cacatcatcc 3600

 actttatccc agaaactaga actgtgagaa accaggttta gaagacagtc 3650

 acagaacagc acacatccaa attcagcgcc attgaaagtt ggcctaaggc 3700

 tcagtgccac tcacccctcc ctccccaaaa gacaagagaa atttggccag 3750

 atggggaagg tcactggaaa ttgaggccaa agggctgatc agaattgcct 3800

 ttataatata tttgatggat gcctataaat gtgggttttg caaatattgt 3850

 ttaaaaacca aacttgaagc caggcatggt ggcccacacc tgtggtccca 3900

 gctactcagg aggctgaggt gggaggatca tttgagccca ggaggtcaag 3950

 gctgcagtga gctgtgatga caccactgca ctccaaccta ggtaacagag 4000

 agacacctct gtctctgaaa aaacaaaact tgaagtttga aacccccagc 4050

 ttgctgagga gcccttttta tttttggtac tgagagtctc aaggtcccat 4100

 agctacatgg tacagggctg ttgtctgctt gctgcacagc agaaattaca 4150

 ccatccacag gaaatggact atttttgcag tccaacatca gccaaccaca 4200

 cacagccgtg tttggaagct gaagagtaaa gaaatttcta ggaatggctg 4250

 ttgttctgtt ttttagcaca gccatttaga tataacatcc ttcacttaaa 4300

 aattaaaaac atcagtacta ccaccaccac caacaacatc aacacagatc 4350

 ttcacatctg cccattctgt ggttagtcaa tggcttgcaa taaatgtgca 4400

 aactgcatct ataggaaaca tttttgtgat tacggaatac tttagttgat 4450

 tgctgaaaat attgaaaggt cttcatttta cagtgatgag tacatatgca 4500

 tgtttcgggg acttggccct tctgatgagg ggccctcggt actctggata 4550

 acgaagcttg tgcagagtgg taaccatgct tacacactaa actataatat 4600

 aaaggaaatg aagccatgtt aatctgagag cagtgtcgcc atagttgtgt 4650

 tgtttacaat actctataaa tgggttcctg ttgccctgta attaaactgc 4700

 tgcccgtaga ggcctttcag ttccttttct gtccttcccc ttcttaacac 4750

 aagctcaaat tttctaactt gtttttattt tgaagacttt taaaatggac 4800

 attttcaata cataaaaata aacagtgctt tataaaaat 4839

<210> 2039
<211> 776
<212> PRT
<213> Homo sapien

<400> 2039
 Met Asn Pro Glu Glu Gln Ile Val Thr Trp Leu Ile Ser Leu Gly
   1               5                  10                  15

 Val Leu Glu Ser Pro Lys Lys Thr Ile Cys Asp Pro Glu Glu Phe
                  20                  25                  30

 Leu Lys Ser Ser Leu Lys Asn Gly Val Val Leu Cys Lys Leu Ile
                  35                  40                  45

 Asn Arg Leu Met Pro Gly Ser Val Glu Lys Phe Cys Leu Asp Pro
                  50                  55                  60

 Gln Thr Glu Ala Asp Cys Ile Asn Asn Ile Asn Asp Phe Leu Lys
                  65                  70                  75

 Gly Cys Ala Thr Leu Gln Val Glu Ile Phe Asp Pro Asp Asp Leu
                  80                  85                  90

 Tyr Ser Gly Val Asn Phe Ser Lys Val Leu Ser Thr Leu Leu Ala
                  95                 100                 105

 Val Asn Lys Ala Thr Glu Asp Gln Leu Ser Glu Arg Pro Cys Gly
                 110                 115                 120

 Arg Ser Ser Ser Leu Ser Ala Ala Asn Thr Ser Gln Thr Asn Pro
                 125                 130                 135

 Gln Gly Ala Val Ser Ser Thr Val Ser Gly Leu Gln Arg Gln Ser
                 140                 145                 150

 Lys Thr Val Glu Met Thr Glu Asn Gly Ser His Gln Leu Ile Val
                 155                 160                 165

 Lys Ala Arg Phe Asn Phe Lys Gln Thr Asn Glu Asp Glu Leu Ser
                 170                 175                 180

 Val Cys Lys Gly Asp Ile Ile Tyr Val Thr Arg Val Glu Glu Gly
                 185                 190                 195

 Gly Trp Trp Glu Gly Thr Leu Asn Gly Arg Thr Gly Trp Phe Pro
                 200                 205                 210

 Ser Asn Tyr Val Arg Glu Ile Lys Ser Ser Glu Arg Pro Leu Ser
                 215                 220                 225

 Pro Lys Ala Val Lys Gly Phe Glu Thr Ala Pro Leu Thr Lys Asn
                 230                 235                 240

 Tyr Tyr Thr Val Val Leu Gln Asn Ile Leu Asp Thr Glu Lys Glu
                 245                 250                 255

 Tyr Ala Lys Glu Leu Gln Ser Leu Leu Val Thr Tyr Leu Arg Pro
                 260                 265                 270

 Leu Gln Ser Asn Asn Asn Leu Ser Thr Val Glu Val Thr Ser Leu
                 275                 280                 285

 Leu Gly Asn Phe Glu Glu Val Cys Thr Phe Gln Gln Thr Leu Cys
                 290                 295                 300

 Gln Ala Leu Glu Glu Cys Ser Lys Phe Pro Glu Asn Gln His Lys
                 305                 310                 315

 Val Gly Gly Cys Leu Leu Ser Leu Met Pro His Phe Lys Ser Met
                 320                 325                 330

 Tyr Leu Ala Tyr Cys Ala Asn His Pro Ser Ala Val Asn Val Leu
                 335                 340                 345

 Thr Gln His Ser Asp Glu Leu Glu Gln Phe Met Glu Asn Gln Gly
                 350                 355                 360

 Ala Ser Ser Pro Gly Ile Leu Ile Leu Thr Thr Asn Leu Ser Lys
                 365                 370                 375

 Pro Phe Met Arg Leu Glu Lys Tyr Val Thr Leu Leu Gln Glu Leu
                 380                 385                 390

 Glu Arg His Met Glu Asp Thr His Pro Asp His Gln Asp Ile Leu
                 395                 400                 405

 Lys Ala Ile Val Ala Phe Lys Thr Leu Met Gly Gln Cys Gln Asp
                 410                 415                 420

 Leu Arg Lys Arg Lys Gln Leu Glu Leu Gln Ile Leu Ser Glu Pro
                 425                 430                 435

 Ile Gln Ala Trp Glu Gly Glu Asp Ile Lys Asn Leu Gly Asn Val
                 440                 445                 450

 Ile Phe Met Ser Gln Val Met Val Gln Tyr Gly Ala Cys Glu Glu
                 455                 460                 465

 Lys Glu Glu Arg Tyr Leu Met Leu Phe Ser Asn Val Leu Ile Met
                 470                 475                 480

 Leu Ser Ala Ser Pro Arg Met Ser Gly Phe Ile Tyr Gln Gly Lys
                 485                 490                 495

 Ile Pro Ile Ala Gly Thr Val Val Thr Arg Leu Asp Glu Ile Glu
                 500                 505                 510

 Gly Asn Asp Cys Thr Phe Glu Ile Thr Gly Asn Thr Val Glu Arg
                 515                 520                 525

 Ile Val Val His Cys Asn Asn Asn Gln Asp Phe Gln Glu Trp Leu
                 530                 535                 540

 Glu Gln Leu Asn Arg Leu Ile Arg Gly Pro Ala Ser Cys Ser Ser
                 545                 550                 555

 Leu Ser Lys Thr Ser Ser Ser Ser Cys Ser Ala His Ser Ser Phe
                 560                 565                 570

 Ser Ser Thr Gly Gln Pro Arg Gly Pro Leu Glu Pro Pro Gln Ile
                 575                 580                 585

 Ile Lys Pro Trp Ser Leu Ser Cys Leu Arg Pro Ala Pro Pro Leu
                 590                 595                 600

 Arg Pro Ser Ala Ala Leu Gly Tyr Lys Glu Arg Met Ser Tyr Ile
                 605                 610                 615

 Leu Lys Glu Ser Ser Lys Ser Pro Lys Thr Met Lys Lys Phe Leu
                 620                 625                 630

 His Lys Arg Lys Thr Glu Arg Lys Pro Ser Glu Glu Glu Tyr Val
                 635                 640                 645

 Ile Arg Lys Ser Thr Ala Ala Leu Glu Glu Asp Ala Gln Ile Leu
                 650                 655                 660

 Lys Val Ile Glu Ala Tyr Cys Thr Ser Ala Asn Phe Gln Gln Gly
                 665                 670                 675

 His Gly Ser Ser Thr Arg Lys Asp Ser Ile Pro Gln Val Leu Leu
                 680                 685                 690

 Pro Glu Glu Glu Lys Leu Ile Ile Glu Glu Thr Arg Ser Asn Gly
                 695                 700                 705

 Gln Thr Ile Met Glu Glu Lys Ser Leu Val Asp Thr Val Tyr Ala
                 710                 715                 720

 Leu Lys Asp Glu Val Arg Glu Leu Lys Gln Glu Asn Lys Arg Met
                 725                 730                 735

 Lys Gln Cys Leu Glu Glu Glu Leu Lys Ser Arg Arg Asp Leu Glu
                 740                 745                 750

 Lys Leu Val Arg Arg Leu Leu Lys Gln Thr Asp Glu Cys Ile Arg
                 755                 760                 765

 Gly Glu Ser Ser Ser Lys Thr Ser Ile Leu Pro
                 770                 775

<210> 2040
<211> 7260
<212> DNA
<213> Homo sapien

<400> 2040
 tcactgtcac tgctaaattc agagcagatt agagcctgcg caatggaata 50

 aagtcctcaa aattgaaatg tgacattgct ctcaacatct cccatctctc 100

 tggatttcct tttgcttcat tattcctgct aaccaattca ttttcagact 150

 ttgtacttca gaagcaatgg gaaaaatcag cagtcttcca acccaattat 200

 ttaagtgctg cttttgtgat ttcttgaagg tgaagatgca caccatgtcc 250

 tcctcgcatc tcttctacct ggcgctgtgc ctgctcacct tcaccagctc 300

 tgccacggct ggaccggaga cgctctgcgg ggctgagctg gtggatgctc 350

 ttcagttcgt gtgtggagac aggggctttt atttcaacaa gcccacaggg 400

 tatggctcca gcagtcggag ggcgcctcag acaggcatcg tggatgagtg 450

 ctgcttccgg agctgtgatc taaggaggct ggagatgtat tgcgcacccc 500

 tcaagcctgc caagtcagct cgctctgtcc gtgcccagcg ccacaccgac 550

 atgcccaaga cccagaagga agtacatttg aagaacgcaa gtagagggag 600

 tgcaggaaac aagaactaca ggatgtagga agaccctcct gaggagtgaa 650

 gagtgacatg ccaccgcagg atcctttgct ctgcacgagt tacctgttaa 700

 actttggaac acctaccaaa aaataagttt gataacattt aaaagatggg 750

 cgtttccccc aatgaaatac acaagtaaac attccaacat tgtctttagg 800

 agtgatttgc accttgcaaa aatggtcctg gagttggtag attgctgttg 850

 atcttttatc aataatgttc tatagaaaag aaaaaaaaat atatatatat 900

 atatatctta gtccctgcct ctcaagagcc acaaatgcat gggtgttgta 950

 tagatccagt tgcactaaat tcctctctga atcttggctg ctggagccat 1000

 tcattcagca accttgtcta agtggtttat gaattgtttc cttatttgca 1050

 cttctttcta cacaactcgg gctgtttgtt ttacagtgtc tgataatctt 1100

 gttagtctat acccaccacc tcccttcata acctttatat ttgccgaatt 1150

 tggcctcctc aaaagcagca gcaagtcgtc aagaagcaca ccaattctaa 1200

 cccacaagat tccatctgtg gcatttgtac caaatataag ttggatgcat 1250

 tttattttag acacaaagct ttatttttcc acatcatgct tacaaaaaag 1300

 aataatgcaa atagttgcaa ctttgaggcc aatcattttt aggcatatgt 1350

 tttaaacata gaaagtttct tcaactcaaa agagttcctt caaatgatga 1400

 gttaatgtgc aacctaatta gtaactttcc tctttttatt ttttccatat 1450

 agagcactat gtaaatttag catatcaatt atacaggata tatcaaacag 1500

 tatgtaaaac tctgtttttt agtataatgg tgctattttg tagtttgtta 1550

 tatgaaagag tctggccaaa acggtaatac gtgaaagcaa aacaataggg 1600

 gaagcctgga gccaaagatg acacaagggg aagggtactg aaaacaccat 1650

 ccatttggga aagaaggcaa agtcccccca gttatgcctt ccaagaggaa 1700

 cttcagacac aaaagtccac tgatgcaaat tggactggcg agtccagaga 1750

 ggaaactgtg gaatggaaaa agcagaaggc taggaatttt agcagtcctg 1800

 gtttcttttt ctcatggaag aaatgaacat ctgccagctg tgtcatggac 1850

 tcaccactgt gtgaccttgg gcaagtcact tcacctctct gtgcctcagt 1900

 ttcctcatct gcaaaatggg ggcaatatgt catctaccta cctcaaaggg 1950

 gtggtataag gtttaaaaag ataaagattc agattttttt accctgggtt 2000

 gctgtaaggg tgcaacatca gggcgcttga gttgctgaga tgcaaggaat 2050

 tctataaata acccattcat agcatagcta gagattggtg aattgaatgc 2100

 tcctgacatc tcagttcttg tcagtgaagc tatccaaata actggccaac 2150

 tagttgttaa aagctaacag ctcaatctct taaaacactt ttcaaaatat 2200

 gtgggaagca tttgattttc aatttgattt tgaattctgc atttggtttt 2250

 atgaatacaa agataagtga aaagagagaa aggaaaagaa aaaggagaaa 2300

 aacaaagaga tttctaccag tgaaagggga attaattact ctttgttagc 2350

 actcactgac tcttctatgc agttactaca tatctagtaa aaccttgttt 2400

 aatactataa ataatattct attcattttg aaaaacacaa tgattccttc 2450

 ttttctaggc aatataagga aagtgatcca aaatttgaaa tattaaaata 2500

 atatctaata aaaagtcaca aagttatctt ctttaacaaa ctttactctt 2550

 attcttagct gtatatacat ttttttaaaa agtttgttaa aatatgcttg 2600

 actagagttt cagttgaaag gcaaaaactt ccatcacaac aagaaatttc 2650

 ccatgcctgc tcagaagggt agcccctagc tctctgtgaa tgtgttttat 2700

 ccattcaact gaaaattggt atcaagaaag tccactggtt agtgtactag 2750

 tccatcatag cctagaaaat gatccctatc tgcagatcaa gattttctca 2800

 ttagaacaat gaattatcca gcattcagat ctttctagtc accttagaac 2850

 tttttggtta aaagtaccca ggcttgatta tttcatgcaa attctatatt 2900

 ttacattctt ggaaagtcta tatgaaaaac aaaaataaca tcttcagttt 2950

 ttctcccact gggtcacctc aaggatcaga ggccaggaaa aaaaaaaaag 3000

 actccctgga tctctgaata tatgcaaaaa gaaggcccca tttagtggag 3050

 ccagcaatcc tgttcagtca acaagtattt taactctcag tccaacatta 3100

 tttgaattga gcacctcaag catgcttagc aatgttctaa tcactatgga 3150

 cagatgtaaa agaaactata catcattttt gccctctgcc tgttttccag 3200

 acatacaggt tctgtggaat aagatactgg actcctcttc ccaagatggc 3250

 acttcttttt atttcttgtc cccagtgtgt accttttaaa attattccct 3300

 ctcaacaaaa ctttataggc agtcttctgc agacttaaca tgttttctgt 3350

 catagttaga tgtgataatt ctaagagtgt ctatgactta tttccttcac 3400

 ttaattctat ccacagtcaa aaatccccca aggaggaaag ctgaaagatg 3450

 caactgccaa tattatcttt cttaactttt tccaacacat aatcctctcc 3500

 aactggatta taaataaatt gaaaataact cattatacca attcactatt 3550

 ttatttttta atgaattaaa actagaaaac aaattgatgc aaaccctgga 3600

 agtcagttga ttactatata ctacagcaga atgactcaga tttcatagaa 3650

 aggagcaacc aaaatgtcac aaccaaaact ttacaagctt tgcttcagaa 3700

 ttagattgct ttataattct tgaatgaggc aatttcaaga tatttgtaaa 3750

 agaacagtaa acattggtaa gaatgagctt tcaactcata ggcttatttc 3800

 caatttaatt gaccatactg gatacttagg tcaaatttct gttctctctt 3850

 gcccaaataa tattaaagta ttatttgaac tttttaagat gaggcagttc 3900

 ccctgaaaaa gttaatgcag ctctccatca gaatccactc ttctagggat 3950

 atgaaaatct cttaacaccc accctacata cacagacaca cacacacaca 4000

 cacacacaca cacacacaca cacacattca ccctaaggat ccaatggaat 4050

 actgaaaaga aatcacttcc ttgaaaattt tattaaaaaa caaacaaaca 4100

 aacaaaaagc ctgtccaccc ttgagaatcc ttcctctcct tggaacgtca 4150

 atgtttgtgt agatgaaacc atctcatgct ctgtggctcc agggtttctg 4200

 ttactatttt atgcacttgg gagaaggctt agaataaaag atgtagcaca 4250

 ttttgctttc ccatttattg tttggccagc tatgccaatg tggtgctatt 4300

 gtttctttaa gaaagtactt gactaaaaaa aaaagaaaaa aagaaaaaaa 4350

 agaaagcata gacatatttt tttaaagtat aaaaacaaca attctataga 4400

 tagatggctt aataaaatag cattaggtct atctagccac caccaccttt 4450

 caacttttta tcactcacaa gtagtgtact gttcaccaaa ttgtgaattt 4500

 gggggtgcag gggcaggagt tggaaatttt ttaaagttag aaggctccat 4550

 tgttttgttg gctctcaaac ttagcaaaat tagcaatata ttatccaatc 4600

 ttctgaactt gatcaagagc atggagaata aacgcgggaa aaaagatctt 4650

 ataggcaaat agaagaattt aaaagataag taagttcctt attgattttt 4700

 gtgcactctg ctctaaaaca gatattcagc aagtggagaa aataagaaca 4750

 aagagaaaaa atacatagat ttacctgcaa aaaatagctt ctgccaaatc 4800

 ccccttgggt attctttggc atttactggt ttatagaaga cattctccct 4850

 tcacccagac atctcaaaga gcagtagctc tcatgaaaag caatcactga 4900

 tctcatttgg gaaatgttgg aaagtatttc cttatgagat gggggttatc 4950

 tactgataaa gaaagaattt atgagaaatt gttgaaagag atggctaaca 5000

 atctgtgaag attttttgtt tcttggtttt gttttttttt ttttttttac 5050

 tttatacagt ctttatgaat ttcttaatgt tcaaaatgac ttggttcttt 5100

 tcttcttttt tttatatcag aatgaggaat aataagttaa acccacatag 5150

 actctttaaa actataggct agatagaaat gtatgtttga cttgttgaag 5200

 ctataatcag actatttaaa atgttttgct atttttaatc ttaaaagatt 5250

 gtgctaattt attagagcag aacctgtttg gctctcctca gaagaaagaa 5300

 tctttccatt caaatcacat ggctttccac caatattttc aaaagataaa 5350

 tctgatttat gcaatggcat catttatttt aaaacagaag aattgtgaaa 5400

 gtttatgccc ctcccttgca aagaccataa agtccagatc tggtaggggg 5450

 gcaacaacaa aaggaaaatg ttgttgattc ttggttttgg attttgtttt 5500

 gttttcaatg ctagtgttta atcctgtagt acatatttgc ttattgctat 5550

 tttaatattt tataagacct tcctgttagg tattagaaag tgatacatag 5600

 atatcttttt tgtgtaattt ctatttaaaa aagagagaag actgtcagaa 5650

 gctttaagtg catatggtac aggataaaga tatcaattta aataaccaat 5700

 tcctatctgg aacaatgctt ttgtttttta aagaaacctc tcacagataa 5750

 gacagaggcc caggggattt ttgaagctgt ctttattctg cccccatccc 5800

 aacccagccc ttattatttt agtatctgcc tcagaatttt atagagggct 5850

 gaccaagctg aaactctaga attaaaggaa cctcactgaa aacatatatt 5900

 tcacgtgttc cctctctttt ttttcctttt tgtgagatgg ggtctcgcac 5950

 tgtcccccag gctggagtgc agtggcatga tctcggctca ctgcaacctc 6000

 cacctcctgg gtttaagcga ttctcctgcc tcagcctcct gagtagctgg 6050

 gattacaggc acccaccact atgcccggct aattttttgg atttttaata 6100

 gagacggggt tttaccatgt tggccaggtt ggactcaaac tcctgacctt 6150

 gtgatttgcc cgcctcagcc tcccaaattg ctgggattac aggcatgagc 6200

 caccacaccc tgcccatgtg ttccctctta atgtatgatt acatggatct 6250

 taaacatgat ccttctctcc tcattcttca actatctttg atggggtctt 6300

 tcaaggggaa aaaaatccaa gcttttttaa agtaaaaaaa aaaaaagaga 6350

 ggacacaaaa ccaaatgtta ctgctcaact gaaatatgag ttaagatgga 6400

 gacagagttt ctcctaataa ccggagctga attacctttc actttcaaaa 6450

 acatgacctt ccacaatcct tagaatctgc ctttttttat attactgagg 6500

 cctaaaagta aacattactc attttatttt gcccaaaatg cactgatgta 6550

 aagtaggaaa aataaaaaca gagctctaaa atccctttca agccacccat 6600

 tgaccccact caccaactca tagcaaagtc acttctgtta atcccttaat 6650

 ctgattttgt ttggatattt atcttgtacc cgctgctaaa cacactgcag 6700

 gagggactct gaaacctcaa gctgtctact tacatctttt atctgtgtct 6750

 gtgtatcatg aaaatgtcta ttcaaaatat caaaaccttt caaatatcac 6800

 gcagcttata ttcagtttac ataaaggccc caaataccat gtcagatctt 6850

 tttggtaaaa gagttaatga actatgagaa ttgggattac atcatgtatt 6900

 ttgcctcatg tatttttatc acacttatag gccaagtgtg ataaataaac 6950

 ttacagacac tgaattaatt tcccctgcta ctttgaaacc agaaaataat 7000

 gactggccat tcgttacatc tgtcttagtt gaaaagcata ttttttatta 7050

 aattaattct gattgtattt gaaattatta ttcaattcac ttatggcaga 7100

 ggaatatcaa tcctaatgac ttctaaaaat gtaactaatt gaatcattat 7150

 cttacattta ctgtttaata agcatatttt gaaaatgtat ggctagagtg 7200

 tcataataaa atggtatatc tttctttagt aattacaaaa aaaaaaaaaa 7250

 aaaaaaaaaa 7260

<210> 2041
<211> 153
<212> PRT
<213> Homo sapien

<400> 2041
 Met Gly Lys Ile Ser Ser Leu Pro Thr Gln Leu Phe Lys Cys Cys
   1               5                  10                  15

 Phe Cys Asp Phe Leu Lys Val Lys Met His Thr Met Ser Ser Ser
                  20                  25                  30

 His Leu Phe Tyr Leu Ala Leu Cys Leu Leu Thr Phe Thr Ser Ser
                  35                  40                  45

 Ala Thr Ala Gly Pro Glu Thr Leu Cys Gly Ala Glu Leu Val Asp
                  50                  55                  60

 Ala Leu Gln Phe Val Cys Gly Asp Arg Gly Phe Tyr Phe Asn Lys
                  65                  70                  75

 Pro Thr Gly Tyr Gly Ser Ser Ser Arg Arg Ala Pro Gln Thr Gly
                  80                  85                  90

 Ile Val Asp Glu Cys Cys Phe Arg Ser Cys Asp Leu Arg Arg Leu
                  95                 100                 105

 Glu Met Tyr Cys Ala Pro Leu Lys Pro Ala Lys Ser Ala Arg Ser
                 110                 115                 120

 Val Arg Ala Gln Arg His Thr Asp Met Pro Lys Thr Gln Lys Glu
                 125                 130                 135

 Val His Leu Lys Asn Ala Ser Arg Gly Ser Ala Gly Asn Lys Asn
                 140                 145                 150

 Tyr Arg Met


<210> 2042
<211> 7260
<212> DNA
<213> Homo sapien

<400> 2042
 tcactgtcac tgctaaattc agagcagatt agagcctgcg caatggaata 50

 aagtcctcaa aattgaaatg tgacattgct ctcaacatct cccatctctc 100

 tggatttcct tttgcttcat tattcctgct aaccaattca ttttcagact 150

 ttgtacttca gaagcaatgg gaaaaatcag cagtcttcca acccaattat 200

 ttaagtgctg cttttgtgat ttcttgaagg tgaagatgca caccatgtcc 250

 tcctcgcatc tcttctacct ggcgctgtgc ctgctcacct tcaccagctc 300

 tgccacggct ggaccggaga cgctctgcgg ggctgagctg gtggatgctc 350

 ttcagttcgt gtgtggagac aggggctttt atttcaacaa gcccacaggg 400

 tatggctcca gcagtcggag ggcgcctcag acaggcatcg tggatgagtg 450

 ctgcttccgg agctgtgatc taaggaggct ggagatgtat tgcgcacccc 500

 tcaagcctgc caagtcagct cgctctgtcc gtgcccagcg ccacaccgac 550

 atgcccaaga cccagaagga agtacatttg aagaacgcaa gtagagggag 600

 tgcaggaaac aagaactaca ggatgtagga agaccctcct gaggagtgaa 650

 gagtgacatg ccaccgcagg atcctttgct ctgcacgagt tacctgttaa 700

 actttggaac acctaccaaa aaataagttt gataacattt aaaagatggg 750

 cgtttccccc aatgaaatac acaagtaaac attccaacat tgtctttagg 800

 agtgatttgc accttgcaaa aatggtcctg gagttggtag attgctgttg 850

 atcttttatc aataatgttc tatagaaaag aaaaaaaaat atatatatat 900

 atatatctta gtccctgcct ctcaagagcc acaaatgcat gggtgttgta 950

 tagatccagt tgcactaaat tcctctctga atcttggctg ctggagccat 1000

 tcattcagca accttgtcta agtggtttat gaattgtttc cttatttgca 1050

 cttctttcta cacaactcgg gctgtttgtt ttacagtgtc tgataatctt 1100

 gttagtctat acccaccacc tcccttcata acctttatat ttgccgaatt 1150

 tggcctcctc aaaagcagca gcaagtcgtc aagaagcaca ccaattctaa 1200

 cccacaagat tccatctgtg gcatttgtac caaatataag ttggatgcat 1250

 tttattttag acacaaagct ttatttttcc acatcatgct tacaaaaaag 1300

 aataatgcaa atagttgcaa ctttgaggcc aatcattttt aggcatatgt 1350

 tttaaacata gaaagtttct tcaactcaaa agagttcctt caaatgatga 1400

 gttaatgtgc aacctaatta gtaactttcc tctttttatt ttttccatat 1450

 agagcactat gtaaatttag catatcaatt atacaggata tatcaaacag 1500

 tatgtaaaac tctgtttttt agtataatgg tgctattttg tagtttgtta 1550

 tatgaaagag tctggccaaa acggtaatac gtgaaagcaa aacaataggg 1600

 gaagcctgga gccaaagatg acacaagggg aagggtactg aaaacaccat 1650

 ccatttggga aagaaggcaa agtcccccca gttatgcctt ccaagaggaa 1700

 cttcagacac aaaagtccac tgatgcaaat tggactggcg agtccagaga 1750

 ggaaactgtg gaatggaaaa agcagaaggc taggaatttt agcagtcctg 1800

 gtttcttttt ctcatggaag aaatgaacat ctgccagctg tgtcatggac 1850

 tcaccactgt gtgaccttgg gcaagtcact tcacctctct gtgcctcagt 1900

 ttcctcatct gcaaaatggg ggcaatatgt catctaccta cctcaaaggg 1950

 gtggtataag gtttaaaaag ataaagattc agattttttt accctgggtt 2000

 gctgtaaggg tgcaacatca gggcgcttga gttgctgaga tgcaaggaat 2050

 tctataaata acccattcat agcatagcta gagattggtg aattgaatgc 2100

 tcctgacatc tcagttcttg tcagtgaagc tatccaaata actggccaac 2150

 tagttgttaa aagctaacag ctcaatctct taaaacactt ttcaaaatat 2200

 gtgggaagca tttgattttc aatttgattt tgaattctgc atttggtttt 2250

 atgaatacaa agataagtga aaagagagaa aggaaaagaa aaaggagaaa 2300

 aacaaagaga tttctaccag tgaaagggga attaattact ctttgttagc 2350

 actcactgac tcttctatgc agttactaca tatctagtaa aaccttgttt 2400

 aatactataa ataatattct attcattttg aaaaacacaa tgattccttc 2450

 ttttctaggc aatataagga aagtgatcca aaatttgaaa tattaaaata 2500

 atatctaata aaaagtcaca aagttatctt ctttaacaaa ctttactctt 2550

 attcttagct gtatatacat ttttttaaaa agtttgttaa aatatgcttg 2600

 actagagttt cagttgaaag gcaaaaactt ccatcacaac aagaaatttc 2650

 ccatgcctgc tcagaagggt agcccctagc tctctgtgaa tgtgttttat 2700

 ccattcaact gaaaattggt atcaagaaag tccactggtt agtgtactag 2750

 tccatcatag cctagaaaat gatccctatc tgcagatcaa gattttctca 2800

 ttagaacaat gaattatcca gcattcagat ctttctagtc accttagaac 2850

 tttttggtta aaagtaccca ggcttgatta tttcatgcaa attctatatt 2900

 ttacattctt ggaaagtcta tatgaaaaac aaaaataaca tcttcagttt 2950

 ttctcccact gggtcacctc aaggatcaga ggccaggaaa aaaaaaaaag 3000

 actccctgga tctctgaata tatgcaaaaa gaaggcccca tttagtggag 3050

 ccagcaatcc tgttcagtca acaagtattt taactctcag tccaacatta 3100

 tttgaattga gcacctcaag catgcttagc aatgttctaa tcactatgga 3150

 cagatgtaaa agaaactata catcattttt gccctctgcc tgttttccag 3200

 acatacaggt tctgtggaat aagatactgg actcctcttc ccaagatggc 3250

 acttcttttt atttcttgtc cccagtgtgt accttttaaa attattccct 3300

 ctcaacaaaa ctttataggc agtcttctgc agacttaaca tgttttctgt 3350

 catagttaga tgtgataatt ctaagagtgt ctatgactta tttccttcac 3400

 ttaattctat ccacagtcaa aaatccccca aggaggaaag ctgaaagatg 3450

 caactgccaa tattatcttt cttaactttt tccaacacat aatcctctcc 3500

 aactggatta taaataaatt gaaaataact cattatacca attcactatt 3550

 ttatttttta atgaattaaa actagaaaac aaattgatgc aaaccctgga 3600

 agtcagttga ttactatata ctacagcaga atgactcaga tttcatagaa 3650

 aggagcaacc aaaatgtcac aaccaaaact ttacaagctt tgcttcagaa 3700

 ttagattgct ttataattct tgaatgaggc aatttcaaga tatttgtaaa 3750

 agaacagtaa acattggtaa gaatgagctt tcaactcata ggcttatttc 3800

 caatttaatt gaccatactg gatacttagg tcaaatttct gttctctctt 3850

 gcccaaataa tattaaagta ttatttgaac tttttaagat gaggcagttc 3900

 ccctgaaaaa gttaatgcag ctctccatca gaatccactc ttctagggat 3950

 atgaaaatct cttaacaccc accctacata cacagacaca cacacacaca 4000

 cacacacaca cacacacaca cacacattca ccctaaggat ccaatggaat 4050

 actgaaaaga aatcacttcc ttgaaaattt tattaaaaaa caaacaaaca 4100

 aacaaaaagc ctgtccaccc ttgagaatcc ttcctctcct tggaacgtca 4150

 atgtttgtgt agatgaaacc atctcatgct ctgtggctcc agggtttctg 4200

 ttactatttt atgcacttgg gagaaggctt agaataaaag atgtagcaca 4250

 ttttgctttc ccatttattg tttggccagc tatgccaatg tggtgctatt 4300

 gtttctttaa gaaagtactt gactaaaaaa aaaagaaaaa aagaaaaaaa 4350

 agaaagcata gacatatttt tttaaagtat aaaaacaaca attctataga 4400

 tagatggctt aataaaatag cattaggtct atctagccac caccaccttt 4450

 caacttttta tcactcacaa gtagtgtact gttcaccaaa ttgtgaattt 4500

 gggggtgcag gggcaggagt tggaaatttt ttaaagttag aaggctccat 4550

 tgttttgttg gctctcaaac ttagcaaaat tagcaatata ttatccaatc 4600

 ttctgaactt gatcaagagc atggagaata aacgcgggaa aaaagatctt 4650

 ataggcaaat agaagaattt aaaagataag taagttcctt attgattttt 4700

 gtgcactctg ctctaaaaca gatattcagc aagtggagaa aataagaaca 4750

 aagagaaaaa atacatagat ttacctgcaa aaaatagctt ctgccaaatc 4800

 ccccttgggt attctttggc atttactggt ttatagaaga cattctccct 4850

 tcacccagac atctcaaaga gcagtagctc tcatgaaaag caatcactga 4900

 tctcatttgg gaaatgttgg aaagtatttc cttatgagat gggggttatc 4950

 tactgataaa gaaagaattt atgagaaatt gttgaaagag atggctaaca 5000

 atctgtgaag attttttgtt tcttggtttt gttttttttt ttttttttac 5050

 tttatacagt ctttatgaat ttcttaatgt tcaaaatgac ttggttcttt 5100

 tcttcttttt tttatatcag aatgaggaat aataagttaa acccacatag 5150

 actctttaaa actataggct agatagaaat gtatgtttga cttgttgaag 5200

 ctataatcag actatttaaa atgttttgct atttttaatc ttaaaagatt 5250

 gtgctaattt attagagcag aacctgtttg gctctcctca gaagaaagaa 5300

 tctttccatt caaatcacat ggctttccac caatattttc aaaagataaa 5350

 tctgatttat gcaatggcat catttatttt aaaacagaag aattgtgaaa 5400

 gtttatgccc ctcccttgca aagaccataa agtccagatc tggtaggggg 5450

 gcaacaacaa aaggaaaatg ttgttgattc ttggttttgg attttgtttt 5500

 gttttcaatg ctagtgttta atcctgtagt acatatttgc ttattgctat 5550

 tttaatattt tataagacct tcctgttagg tattagaaag tgatacatag 5600

 atatcttttt tgtgtaattt ctatttaaaa aagagagaag actgtcagaa 5650

 gctttaagtg catatggtac aggataaaga tatcaattta aataaccaat 5700

 tcctatctgg aacaatgctt ttgtttttta aagaaacctc tcacagataa 5750

 gacagaggcc caggggattt ttgaagctgt ctttattctg cccccatccc 5800

 aacccagccc ttattatttt agtatctgcc tcagaatttt atagagggct 5850

 gaccaagctg aaactctaga attaaaggaa cctcactgaa aacatatatt 5900

 tcacgtgttc cctctctttt ttttcctttt tgtgagatgg ggtctcgcac 5950

 tgtcccccag gctggagtgc agtggcatga tctcggctca ctgcaacctc 6000

 cacctcctgg gtttaagcga ttctcctgcc tcagcctcct gagtagctgg 6050

 gattacaggc acccaccact atgcccggct aattttttgg atttttaata 6100

 gagacggggt tttaccatgt tggccaggtt ggactcaaac tcctgacctt 6150

 gtgatttgcc cgcctcagcc tcccaaattg ctgggattac aggcatgagc 6200

 caccacaccc tgcccatgtg ttccctctta atgtatgatt acatggatct 6250

 taaacatgat ccttctctcc tcattcttca actatctttg atggggtctt 6300

 tcaaggggaa aaaaatccaa gcttttttaa agtaaaaaaa aaaaaagaga 6350

 ggacacaaaa ccaaatgtta ctgctcaact gaaatatgag ttaagatgga 6400

 gacagagttt ctcctaataa ccggagctga attacctttc actttcaaaa 6450

 acatgacctt ccacaatcct tagaatctgc ctttttttat attactgagg 6500

 cctaaaagta aacattactc attttatttt gcccaaaatg cactgatgta 6550

 aagtaggaaa aataaaaaca gagctctaaa atccctttca agccacccat 6600

 tgaccccact caccaactca tagcaaagtc acttctgtta atcccttaat 6650

 ctgattttgt ttggatattt atcttgtacc cgctgctaaa cacactgcag 6700

 gagggactct gaaacctcaa gctgtctact tacatctttt atctgtgtct 6750

 gtgtatcatg aaaatgtcta ttcaaaatat caaaaccttt caaatatcac 6800

 gcagcttata ttcagtttac ataaaggccc caaataccat gtcagatctt 6850

 tttggtaaaa gagttaatga actatgagaa ttgggattac atcatgtatt 6900

 ttgcctcatg tatttttatc acacttatag gccaagtgtg ataaataaac 6950

 ttacagacac tgaattaatt tcccctgcta ctttgaaacc agaaaataat 7000

 gactggccat tcgttacatc tgtcttagtt gaaaagcata ttttttatta 7050

 aattaattct gattgtattt gaaattatta ttcaattcac ttatggcaga 7100

 ggaatatcaa tcctaatgac ttctaaaaat gtaactaatt gaatcattat 7150

 cttacattta ctgtttaata agcatatttt gaaaatgtat ggctagagtg 7200

 tcataataaa atggtatatc tttctttagt aattacaaaa aaaaaaaaaa 7250

 aaaaaaaaaa 7260

<210> 2043
<211> 153
<212> PRT
<213> Homo sapien

<400> 2043
 Met Gly Lys Ile Ser Ser Leu Pro Thr Gln Leu Phe Lys Cys Cys
   1               5                  10                  15

 Phe Cys Asp Phe Leu Lys Val Lys Met His Thr Met Ser Ser Ser
                  20                  25                  30

 His Leu Phe Tyr Leu Ala Leu Cys Leu Leu Thr Phe Thr Ser Ser
                  35                  40                  45

 Ala Thr Ala Gly Pro Glu Thr Leu Cys Gly Ala Glu Leu Val Asp
                  50                  55                  60

 Ala Leu Gln Phe Val Cys Gly Asp Arg Gly Phe Tyr Phe Asn Lys
                  65                  70                  75

 Pro Thr Gly Tyr Gly Ser Ser Ser Arg Arg Ala Pro Gln Thr Gly
                  80                  85                  90

 Ile Val Asp Glu Cys Cys Phe Arg Ser Cys Asp Leu Arg Arg Leu
                  95                 100                 105

 Glu Met Tyr Cys Ala Pro Leu Lys Pro Ala Lys Ser Ala Arg Ser
                 110                 115                 120

 Val Arg Ala Gln Arg His Thr Asp Met Pro Lys Thr Gln Lys Glu
                 125                 130                 135

 Val His Leu Lys Asn Ala Ser Arg Gly Ser Ala Gly Asn Lys Asn
                 140                 145                 150

 Tyr Arg Met


<210> 2044
<211> 1718
<212> DNA
<213> Homo sapien

<400> 2044
 ggcacgaggc acgtggttat gctgccggag tttgggccgc cactgtagga 50

 aaagtaactt cagctgcagc cccaaagcga gtgagccgag ccggagccat 100

 ggagggccag agcgtggagg agctgctcgc aaaggcagag caggacgagg 150

 cagagaagtt gcaacgcatc acggtgcaca aggagctgga gctgcagttt 200

 gacctgggca acctgctggc gtcggaccgg aaccccccga ccgggctgcg 250

 gtgcgccgga cccacgccgg aggccgagct acaggccctg gcgcgggaca 300

 acacgcaact gctcatcaac cagctgtggc agctgcccac ggagcgcgtg 350

 gaagaggcga tagtggcgcg gctgccggag cccaccacac gcctgccgcg 400

 agagaagcct ctgccccgac cgcggccact tacacgctgg cagcagttcg 450

 cgcgcctcaa gggcatccgt cccaagaaga agaccaacct ggtgtgggac 500

 gaggtgagtg gccagtggcg gcggcgctgg ggctaccagc gcgcccggga 550

 cgacaccaaa gaatggctga ttgaggtgcc cggcaatgcc gaccccttgg 600

 aggaccagtt cgccaagcgg attcaggcca agaaggaaag ggtggccaag 650

 aacgagctga accggctgcg taacctggcc cgcgcgcaca agatgcagct 700

 gcccagcgcg gccggcttgc accctaccgg acaccagagt aaggaggagc 750

 tgggccgcgc catgcaagtg gccaaggtct ccaccgcctc tgtggggcgc 800

 tttcaggagc gcctccccaa ggagaaggtg ccccggggct ccggcaagaa 850

 aaggaagttt caaccccttt tcggggactt tgcagccgag aaaaagaacc 900

 agttggagct gcttcgtgtc atgaacagca agaagcctca gctggatgtg 950

 actagggcca ccaataagca gatgagggag gaggaccagg aggaggccgc 1000

 caagaggagg aaaatgagcc agaagggcaa gagaaaggga ggccggcagg 1050

 ggcctggggg caagaggaaa gggggcccgc ccagccaggg agggaagagg 1100

 aaagggggct tgggaggcaa gatgaattct gggccgcctg gcttgggtgg 1150

 caagagaaaa ggaggacagc gcccaggagg aaagaggagg aagtaatagt 1200

 ttctaactgt cggacccgtc tgtaaaccaa ggactatgaa tactaaatgt 1250

 taagttctag gcaattatac ggggactcag aaggacctgg ccgctgcctt 1300

 cattgagttt aaagggacag gattgccctt ccgtcaagaa agtatgtaag 1350

 tgttggactg cacaaattaa tgtttttccc acaaccgaga ctttggagat 1400

 taagaactta tttgaggatt taagaattag ggaaataatt tggtggaaac 1450

 cgggaatgag ttctattctt aaacagcctt tttttttctt tttaatgttg 1500

 gatatacggc gaggtagagt tggccatatt tcagagactt agattgacgt 1550

 atatgtttct gcattatttt tacaacaagt ttgtgtatca gagcgggagt 1600

 gcgggggagg gaaagaaaac aaacagtttc agaattgaat aggcaagtga 1650

 ctgttttaaa gattaagtaa taaagatgtc ttatctagtg tgacttttaa 1700

 aaaaaaaaaa aaaaaaaa 1718

<210> 2045
<211> 365
<212> PRT
<213> Homo sapien

<400> 2045
 Met Glu Gly Gln Ser Val Glu Glu Leu Leu Ala Lys Ala Glu Gln
   1               5                  10                  15

 Asp Glu Ala Glu Lys Leu Gln Arg Ile Thr Val His Lys Glu Leu
                  20                  25                  30

 Glu Leu Gln Phe Asp Leu Gly Asn Leu Leu Ala Ser Asp Arg Asn
                  35                  40                  45

 Pro Pro Thr Gly Leu Arg Cys Ala Gly Pro Thr Pro Glu Ala Glu
                  50                  55                  60

 Leu Gln Ala Leu Ala Arg Asp Asn Thr Gln Leu Leu Ile Asn Gln
                  65                  70                  75

 Leu Trp Gln Leu Pro Thr Glu Arg Val Glu Glu Ala Ile Val Ala
                  80                  85                  90

 Arg Leu Pro Glu Pro Thr Thr Arg Leu Pro Arg Glu Lys Pro Leu
                  95                 100                 105

 Pro Arg Pro Arg Pro Leu Thr Arg Trp Gln Gln Phe Ala Arg Leu
                 110                 115                 120

 Lys Gly Ile Arg Pro Lys Lys Lys Thr Asn Leu Val Trp Asp Glu
                 125                 130                 135

 Val Ser Gly Gln Trp Arg Arg Arg Trp Gly Tyr Gln Arg Ala Arg
                 140                 145                 150

 Asp Asp Thr Lys Glu Trp Leu Ile Glu Val Pro Gly Asn Ala Asp
                 155                 160                 165

 Pro Leu Glu Asp Gln Phe Ala Lys Arg Ile Gln Ala Lys Lys Glu
                 170                 175                 180

 Arg Val Ala Lys Asn Glu Leu Asn Arg Leu Arg Asn Leu Ala Arg
                 185                 190                 195

 Ala His Lys Met Gln Leu Pro Ser Ala Ala Gly Leu His Pro Thr
                 200                 205                 210

 Gly His Gln Ser Lys Glu Glu Leu Gly Arg Ala Met Gln Val Ala
                 215                 220                 225

 Lys Val Ser Thr Ala Ser Val Gly Arg Phe Gln Glu Arg Leu Pro
                 230                 235                 240

 Lys Glu Lys Val Pro Arg Gly Ser Gly Lys Lys Arg Lys Phe Gln
                 245                 250                 255

 Pro Leu Phe Gly Asp Phe Ala Ala Glu Lys Lys Asn Gln Leu Glu
                 260                 265                 270

 Leu Leu Arg Val Met Asn Ser Lys Lys Pro Gln Leu Asp Val Thr
                 275                 280                 285

 Arg Ala Thr Asn Lys Gln Met Arg Glu Glu Asp Gln Glu Glu Ala
                 290                 295                 300

 Ala Lys Arg Arg Lys Met Ser Gln Lys Gly Lys Arg Lys Gly Gly
                 305                 310                 315

 Arg Gln Gly Pro Gly Gly Lys Arg Lys Gly Gly Pro Pro Ser Gln
                 320                 325                 330

 Gly Gly Lys Arg Lys Gly Gly Leu Gly Gly Lys Met Asn Ser Gly
                 335                 340                 345

 Pro Pro Gly Leu Gly Gly Lys Arg Lys Gly Gly Gln Arg Pro Gly
                 350                 355                 360

 Gly Lys Arg Arg Lys
                 365

<210> 2046
<211> 2006
<212> DNA
<213> Mus musculus

<400> 2046
 ctagcagcgg gtcggagatc gaaggaacgg gccaattgcg gctgaaacgt 50

 ctttggaagg aggaaggggg tgagggagca tccctttgag tttcgcctct 100

 tctcgaggcg gtggtgggaa gggagacata cttaatactg ccctcttaat 150

 ccaacggacc ttacatcgtg tagactgccg ggagggcggc gggaaaaggg 200

 caagacggga gttggggaag ggaaggagcc aggaagccgc gcgggagggc 250

 gcgcgcgcgc gccccttttt cagcagtgtg gcggggtcgc acgcacgccc 300

 gcctcggcgg ctgggcgcga tttgcgacag tggggggggc ggtggaggtg 350

 gcggcggcag cggcaacttt gcggcaagct cgggccgggc ttgcttgacg 400

 gcggtgtggc ggaggccccg ccccaggcgg caggaacctg gagggaggcg 450

 gaggaatatg tccgagaggg aagtgtcgac tgcgccggcg ggaacagaca 500

 tgcctgcggc caagaagcag aagctgagca gtgacgagaa cagcaatcca 550

 gacctctctg gagacgagaa tgatgacgct gtcagtatag aaagtggtac 600

 aaacactgaa cgccctgata cacctacaaa cacgccaaat gcacctggaa 650

 ggaaaagttg gggaaaggga aaatggaagt caaagaaatg caaatattct 700

 ttcaaatgtg taaatagtct caaggaagat cataaccaac cattgtttgg 750

 agttcagttt aactggcaca gtaaagaagg agatccatta gtgtttgcaa 800

 ctgtaggaag caacagagtt accttgtatg aatgtcattc acaaggagaa 850

 atccggttgt tgcaatctta cgtggatgct gatgctgatg aaaactttta 900

 cacttgtgca tggacctatg atagcaatac gagccatcct ctgctggctg 950

 tagctggatc tagaggcata attaggataa taaatcctat aacaatgcag 1000

 tgtataaagc actatgttgg ccatggaaat gctatcaatg agctgaaatt 1050

 ccatccaaga gatccaaatc ttctcctgtc agtaagtaaa gatcatgctt 1100

 tacgattatg gaatatccag acggacactc tggtggcaat atttggaggc 1150

 gtagaagggc acagagatga agttctaagt gctgattatg atcttttggg 1200

 tgaaaaaata atgtcctgtg gtatggatca ttctcttaaa ctttggagga 1250

 tcaattcaaa gagaatgatg aatgcaatta aggaatctta tgattataat 1300

 ccaaataaaa ctaacaggcc atttatttct cagaaaatcc attttcctga 1350

 tttttctacc agagacatac ataggaatta tgttgattgt gtgcgatggt 1400

 taggcgattt gatactttct aagtcttgtg aaaatgccat tgtgtgctgg 1450

 aaacctggca agatggaaga tgatatagat aaaattaaac ccagtgaatc 1500

 taatgtgact attcttgggc gatttgatta cagccagtgt gacatttggt 1550

 acatgaggtt ttctatggat ttctggcaaa agatgcttgc attgggcaat 1600

 caagttggca aactttatgt ttgggattta gaagtagaag atcctcataa 1650

 agccaaatgt acaacactga ctcatcataa atgtggtgct gctattcgac 1700

 aaaccagttt tagcagggat agcagcattc ttatagctgt ttgtgatgat 1750

 gccagtattt ggcgctggga tcgacttcga taaaatactt ttgcctaatc 1800

 aaaattagag tgtgtttgtt gtctgtgtaa aatagaatta atgtatcttg 1850

 ctagtaaggg cacgtagagc atttagagtt gtctttcagc attcaatcag 1900

 gctgagctga atgtagtgat gtttacattg tttacattct ttgtactgtc 1950

 ttcctgctca gactctactg cttttaataa aaatttattt ttgtaaaaaa 2000

 aaaaaa 2006

<210> 2047
<211> 441
<212> PRT
<213> Mus musculus

<400> 2047
 Met Ser Glu Arg Glu Val Ser Thr Ala Pro Ala Gly Thr Asp Met
   1               5                  10                  15

 Pro Ala Ala Lys Lys Gln Lys Leu Ser Ser Asp Glu Asn Ser Asn
                  20                  25                  30

 Pro Asp Leu Ser Gly Asp Glu Asn Asp Asp Ala Val Ser Ile Glu
                  35                  40                  45

 Ser Gly Thr Asn Thr Glu Arg Pro Asp Thr Pro Thr Asn Thr Pro
                  50                  55                  60

 Asn Ala Pro Gly Arg Lys Ser Trp Gly Lys Gly Lys Trp Lys Ser
                  65                  70                  75

 Lys Lys Cys Lys Tyr Ser Phe Lys Cys Val Asn Ser Leu Lys Glu
                  80                  85                  90

 Asp His Asn Gln Pro Leu Phe Gly Val Gln Phe Asn Trp His Ser
                  95                 100                 105

 Lys Glu Gly Asp Pro Leu Val Phe Ala Thr Val Gly Ser Asn Arg
                 110                 115                 120

 Val Thr Leu Tyr Glu Cys His Ser Gln Gly Glu Ile Arg Leu Leu
                 125                 130                 135

 Gln Ser Tyr Val Asp Ala Asp Ala Asp Glu Asn Phe Tyr Thr Cys
                 140                 145                 150

 Ala Trp Thr Tyr Asp Ser Asn Thr Ser His Pro Leu Leu Ala Val
                 155                 160                 165

 Ala Gly Ser Arg Gly Ile Ile Arg Ile Ile Asn Pro Ile Thr Met
                 170                 175                 180

 Gln Cys Ile Lys His Tyr Val Gly His Gly Asn Ala Ile Asn Glu
                 185                 190                 195

 Leu Lys Phe His Pro Arg Asp Pro Asn Leu Leu Leu Ser Val Ser
                 200                 205                 210

 Lys Asp His Ala Leu Arg Leu Trp Asn Ile Gln Thr Asp Thr Leu
                 215                 220                 225

 Val Ala Ile Phe Gly Gly Val Glu Gly His Arg Asp Glu Val Leu
                 230                 235                 240

 Ser Ala Asp Tyr Asp Leu Leu Gly Glu Lys Ile Met Ser Cys Gly
                 245                 250                 255

 Met Asp His Ser Leu Lys Leu Trp Arg Ile Asn Ser Lys Arg Met
                 260                 265                 270

 Met Asn Ala Ile Lys Glu Ser Tyr Asp Tyr Asn Pro Asn Lys Thr
                 275                 280                 285

 Asn Arg Pro Phe Ile Ser Gln Lys Ile His Phe Pro Asp Phe Ser
                 290                 295                 300

 Thr Arg Asp Ile His Arg Asn Tyr Val Asp Cys Val Arg Trp Leu
                 305                 310                 315

 Gly Asp Leu Ile Leu Ser Lys Ser Cys Glu Asn Ala Ile Val Cys
                 320                 325                 330

 Trp Lys Pro Gly Lys Met Glu Asp Asp Ile Asp Lys Ile Lys Pro
                 335                 340                 345

 Ser Glu Ser Asn Val Thr Ile Leu Gly Arg Phe Asp Tyr Ser Gln
                 350                 355                 360

 Cys Asp Ile Trp Tyr Met Arg Phe Ser Met Asp Phe Trp Gln Lys
                 365                 370                 375

 Met Leu Ala Leu Gly Asn Gln Val Gly Lys Leu Tyr Val Trp Asp
                 380                 385                 390

 Leu Glu Val Glu Asp Pro His Lys Ala Lys Cys Thr Thr Leu Thr
                 395                 400                 405

 His His Lys Cys Gly Ala Ala Ile Arg Gln Thr Ser Phe Ser Arg
                 410                 415                 420

 Asp Ser Ser Ile Leu Ile Ala Val Cys Asp Asp Ala Ser Ile Trp
                 425                 430                 435

 Arg Trp Asp Arg Leu Arg
                 440

<210> 2048
<211> 8093
<212> DNA
<213> Homo sapien

<400> 2048
 ctcagctccc tgtggtgggg gatggcagag gcttcccgct ccccgcagct 50

 ggtttgcaca gcctcccgac tgtgccgtgg tgtctccttc cctaaagtgg 100

 gacagtcgtt tctgtgtcct gctggcctct gaggaacaga cgtgtgtgag 150

 aggccttcag ggcctgatgg ctggggtggt gacagtgcct ggagaatggg 200

 tggggactgg aggggccagg tggctaacca ctctcctctt ccatggcagc 250

 ggagctggag ttcgcccaaa tcatcatcat cgtcgtggtg gtcacggtga 300

 tggtggtggt catcgtctgc ctgctgaacc actacaaagt ctccacgcgg 350

 tccttcatca accgcccgaa ccagagccgg aggcgggagg acgggctgcc 400

 gcaggaaggg tgcctgtggc cttcagacag cgccgcaccg cggctgggcg 450

 cctcggagat catgcatgcc ccgcggtcca gggacaggtt cacagcgccg 500

 tccttcatcc agagggatcg cttcagccgc ttccagccca cctaccccta 550

 tgtgcagcac gagattgatc ttcctcccac catctccctg tccgacggtg 600

 aagagccacc tccttaccag gggccctgca ccctgcagct ccgggaccct 650

 gaacagcaga tggaactcaa ccgagagtcc gtgagggccc cacccaaccg 700

 aaccatattt gacagtgatt taatagacat tgctatgtat agcgggggtc 750

 catgcccacc cagcagcaac tcgggcatca gtgcaagcac ctgcagcagt 800

 aacgggagga tggaggggcc accccccaca tacagcgagg tgatgggcca 850

 ccacccaggc gcctctttcc tccatcacca gcgcagcaac gcacacaggg 900

 gcagcagact gcagtttcag cagaacaatg cagagagcac aatagtaccc 950

 atcaaaggca aagataggaa gcctgggaac ctggtctgat tccttccaac 1000

 gtgcacttca gctggagaaa gaaaccaaga agggaagcgg ccgctgggcc 1050

 cctcctgcgc acagtgttgt tcagtttcac atggtacaaa taagtaaaac 1100

 caaatgagca aacacggtct ttgtttctga ttccttttag gggaattgca 1150

 tgcaaactag actgaaatga tacaaacttc catctggtct gaccgcaaac 1200

 agtgtttatt tggggacagg ggttgggatg ggggtgtggg caggggaaaa 1250

 cagagaacgg gatgctttga agataccatg aaataaaacc cacagaggta 1300

 tttgatgtat ttaattgtga aaggagactt tgcagataaa tgaggccaga 1350

 atggcatgtt ttataattaa ctgaataaag aaggaagcat tattatatat 1400

 tattgtgggg aagaaccagc cagttcgctt tttctcctaa ggtgtggact 1450

 tttattttgt tttaaaaata tgaatcaaaa ttcctgtgtt gtgtgccaag 1500

 gtataaagtg gagaagttag atgagtgcaa ggagctcctt tgtgttgtga 1550

 tgatgtgttt taaaagttgc actatcttaa tgttgaaaat atttacaagg 1600

 gaactgtttt acgtgaagtt ctgtatgttg tcttttcacc tgtggattgt 1650

 aatcaggccc aaggaatatc ctggagtggt ccccagaagc atccaagaaa 1700

 agatatttgg ggacgtagcc taacatttta ccaacttacg taaatcaaaa 1750

 aagtcattat tgttgcagga gtttgcatca aatagcagtg catcgctgaa 1800

 gcttttggag acttttggat ggaagataag atagggaaga ttaagttcca 1850

 gcatttctga cttgttattt tgagttactc tgctactctt aggctgcata 1900

 gtttatgaga aaatgaacac atgcatttat ggatccagta tcatgcagtg 1950

 ctgccctcat cctccagcag tgcaatttct tcagtaattt agattttttt 2000

 cactatagca tgaaatatat tcaaatacat accttatttt atgcaataaa 2050

 ttgtttaaaa tgcaaggtgg ttattctgca tactgttgaa atatgtgact 2100

 cctcagtata ttcccattgc ctctccccct ttcctcgaca gcttagttca 2150

 gttctgcagg gctgctcagt tcacaggagg ctcccagcag ccaccccaca 2200

 tccagcctac acagaacttt cgtgtgggag tggtgtgggt ggtggttttc 2250

 ttatgctttg gaagccccta gaaataatga cggaagaatg ccatgttgct 2300

 gatcgtggta ataagccatt gtgggttatt gtatgtcact agtattagca 2350

 tagcattctt aaaggaatgc agtgttcaaa acctacccaa attccccgca 2400

 ggattttacc aaacccttcc ccaggccagt tttgtactga aggcaagaac 2450

 tggacagtca gagaacagtg gagggggcaa gtgactgaag agcaccgggt 2500

 aaaaagcaca acatgcagtt aaaatgcaaa ctagaaaact aattttaaat 2550

 attgttagtt ttaatatttc ctgatattta caaatattca ttcttatata 2600

 caatgaaaaa aataactttc ttctgcagat gtaagcactg gcttttataa 2650

 gagcagcagc caacacgttt agcagacact gcgcgtggag aagggcttat 2700

 ctgcagtaca ctctgccatg tggagggtgg gcctctgtgg cctcttcaca 2750

 taacaagatg agctggaatg atgattccat gactcccacc tatgcagcct 2800

 taaagccaaa tccgcgtgtg tgtgtttgtg tctgtctgtg ggtctcgaag 2850

 gtgatccgtc ggtgcggtgg ctctgtgctg taactggaga gactgttcca 2900

 aaccccaaga gttgtctgat cctagtctgt tcccttctgc ttcttacctc 2950

 tgtagatagg tcactggttt ttgtttgttt gttttgagga ttggaatttc 3000

 cattacattc atcctttgca cacagtaaca tccacagaac tagtccaact 3050

 cttaaaagga gagaggaaaa acacaggcac cagttgtcag ctcatgctta 3100

 caacctgtgt ggaagtatat acagttgaga gtcacagtgg aggttctgag 3150

 actggattca gtcttgttcc agtgacagtt ggaaggcctc tgctggagag 3200

 acaccagctc tcagggcaga gattggcttg gggccagaag gaccctcccc 3250

 aaccctggag acaccctgaa ggttcactgg ctctccagat tagcctctct 3300

 tcctctgtca ggcaaagatg aggagcccgt gttcccatcg ggccctgctg 3350

 gcagggactt gcagtggatt cttggtcagg tgtgcccaca gatgcggagg 3400

 cgaggtgagt gattccatca tttcagttct cacctgcagt tttggtgaag 3450

 caggagatgc accccacagc tctagctctc aaatggcttc acagtcctta 3500

 cttctctacc tgcctcaaga aggggctcag agcagagact tgtgaattcc 3550

 ttagtaactg tgagtatatg aatgtgttgc acatgtccac agtattggcg 3600

 agataattac ataattcaga tacctttaat catctttcaa gaaagaggct 3650

 cctcccattc aaccacccta gagaactgcc tttgttaaat agttatttaa 3700

 agactcatac atatcaaacc atgactttga aaggtcttcg aggctggggc 3750

 tctgtaatga attagtttaa aagccaaggt cataacatga attgatggtc 3800

 aatttccctt cagcagaagg aaaaggtgat ttagatcagt agctcttttg 3850

 aaggttgtgg ctgacctgtt cataccgtgt cgcctcatgg ctagtgtggc 3900

 gttgaaagag tagcgactgg gaagatacaa cttacacagt ggggcctatt 3950

 gttctttcaa gaaccctttt tttagcttat agaacccatg ggtccagttt 4000

 agtaacgagt gatttaggca atcaatgata ggtttataat cttagattat 4050

 tccagcaaag tgtggattgc attgttagga agaacatttg gtgggaatga 4100

 acactcctgg gcataccgct gacttttgtc ccttgttccc ggtgtaggag 4150

 acccaaggca tcttgaatcc catctataag aacacaatct tccagcatac 4200

 gtttgctttt tcagaaactc tagcattctc tttaaatact gacgcaatcc 4250

 ttaatggaaa agagatttca tgaagcaaat tatgtatttc aatagttctt 4300

 ctatttttag tgtccaaaat ttactaatac agaagcttga caagcatgtc 4350

 ctcaccctcc ccaccacata aacacatgga cacacaccca agccacaaga 4400

 aatcccaaga gagcagaagc gaatttttaa aagatttatc gtgaggactg 4450

 catttccatt cactaatttt ggctcaaact tatgaggcag gaaatagggg 4500

 ccaacagtaa atgggggagg cctcctgaca ccagcagagg aattttgtac 4550

 ccaggcgagg acttcttgaa cttctgcgta tctccgtttg atctctttca 4600

 cctttatttc atcttcataa gaatgagaaa ggctcaaaag gaagcacttt 4650

 tagaaatctt ctctgaccta gaagaatcca tccaaatccc tgccttcctc 4700

 tctgaaccaa cagttccctt ctctgacagg gggccatcct ctatcttcca 4750

 tccagcggct cttcctttta ggaaggctct ggtgcagagc acttcaaata 4800

 tgtcctcagg ccagatactg attgctagta gagagacacc cggcacccag 4850

 tccgaagccc tccctcaaag gaccggctta tggcgttggt cactggcagg 4900

 ctcagagaca ttctactgtg ggcgcaggga gcccggcccc ccatgcagcc 4950

 atgactggat gcgcccccat ctcgggggct tgctgcactg cttgtttatt 5000

 gaattttgct acttagaatg gcaacattaa ctttgtgtac cattcatttt 5050

 ttaaaaattt tccaaagctc ggcagtgtat gaaagaaaaa actgggaaag 5100

 atacttggtt tctgttaact tttgtgttgc ttgcttaagt gattaaagcc 5150

 agtgcttgga gccaagcctt catgccacga acatgctcca cagcctgccc 5200

 tttgctctcc tgctcacact gaccaagaat gccgcgtgct tggcctactg 5250

 aggtgaaagg acaattgaat gacaggtggg caaagggaga acttcccctt 5300

 cttggtgcga ggaaagtcac aaatttaaaa atgttgcttc cagcccagat 5350

 cctaaatgct agttctcagc agctgcgtgg cttaccgttc gccatttcca 5400

 ccaccgccag ctgccagcac cgctacagat cacagagatg tgaacagaca 5450

 atggaaagca ctcttagcct tgcagtggtc tacatttttt aggaaccaat 5500

 atttcagcat tctttattac ccggcacgct gtgtcctttg cagagttcaa 5550

 gtttatgtta ctgccagggt cagacagtca tttgctgctg ctgctgctgc 5600

 tgctgctgct tctcgaactg gatgcattag gaagctgctg tctgagtgta 5650

 ggaatgtctt gctaagaaag caatgtcttc cttcatcctt ttctttcttc 5700

 cctctgcgtg tccttgtttt tgtgtaatgc gggagagggt tagagctata 5750

 gagattatat atacactatc cgtgcacatt atatatatgt agatataccc 5800

 ctatcatgtc agagatctgc atgtcagttt ttcagcaact aaggtgcctc 5850

 atgttctgag ttcagcagat ataggaacca agccgccccc tcctgcactt 5900

 gatgctccca cctttgttgt gcctcactta aaatggtgct tttttcagtt 5950

 gtctgtcttt tcttatgttt ttatttgtaa ggtgctgtat ataagttgaa 6000

 tatattatgc acatatccta cccaatgggt agaacaaaaa gttgttaata 6050

 ctgtaatata atgtatagat gataccaatt ttaacagaaa tggcatagaa 6100

 tttgtgaatg cctatgtgct ttgtcctctt ttgtaaggaa atttgcaaat 6150

 ggatgcatac agattaaagt ctatgtagtt tattttccta ttaaatatca 6200

 atattataac acaagagaaa gaagtgtgaa caaacaagca acagtttatg 6250

 accagcgtat atatagcaat ggaaagttgc atctttgctg tgaaaacact 6300

 ttaaagaaaa tactttttaa aaaatcccac agctttttgg ttgccactag 6350

 acgcttctta ttttaatcat tttagtaatg ctcagctgga ccagtgttag 6400

 ttatatttga gtcagaaaaa tgttgttttt caacttgctt tataatctcc 6450

 tgcatctatc tcctgctgta gcatcaygaa ggtgtcaggc aacagtgaaa 6500

 agtgcacatt tttgttgttg cagaaactgt gtcagaggaa taagtaaatc 6550

 agcctgcagc agaagacttt gttcagctcc agaggcatct gtgaccgtct 6600

 gtgtccaagt ctctctgtgc ctttttcttt tacaaactga agctgtggag 6650

 ccaatgaagt aacagtagag attgtaggga aagaatacct caggaaaaac 6700

 aaatacactt acaagaagac cctgttctta gaaaatgtgt ttagttatgg 6750

 gttagcacta gaagagactt ggctgtcagc cagccaagtg aaggacctct 6800

 catccattcc cattcatgtc ccatcataat acggacmcaa aaagcaaact 6850

 cggttttgcc atcagttaga aattacgttt tggattgtat attgttacat 6900

 ctctcttcca gcttagtttt tagtgtctga ttgtgacctc tgcatttatc 6950

 ttcaaatacc ctaattttaa aacaaaagaa caagaaaagt ttataacacc 7000

 atgttcacta aaaccacggt tgaatcttgg gtgtgggcat cctttcgagt 7050

 gttgtccata agagcagttc gtggaatttt gcccatctga cccatattat 7100

 cagcttattc tgccaccaga gtagagtcta ataaattcca aagtttttat 7150

 ttgctccatg gtgtatgttc tgactttgaa aatgtcagat tctataatca 7200

 tacccctaac atccaggaga caaatgacag attatcttta aactgaaatt 7250

 gactctacaa tgcaaccctt aatgctgaat ggattaaaaa agtcagccct 7300

 tttagtatct gtttgaaagg gccgtaaaaa gttgacactt ttgttgttgt 7350

 ggatcctgcg tgtctagacc cacgtgttgt ttccatcgta tactgtaggg 7400

 tgcacccctt gggattcatc attaagaact gaggctcact gttgtcagaa 7450

 acaaagctcc caccccccag gttcaacctt gtgggagaac tgttgagcat 7500

 gagaatgttc tagactcaga ggtactaaaa tttgttacca catcattgct 7550

 tcctttctac aggacgaatt gaggcttaaa ctttactgtt aatgatactg 7600

 gttcatttta atgtgcttgt tggtatgttg ctatttttca tttcatagct 7650

 ttcaaaaatc atgctaattg tatacttgtc tagtttaagg ctattttaaa 7700

 atatgtacaa tactattcac agcatttagt tcgtttaatt tttattataa 7750

 agcaatctac taaaaaagta caactgtatt tgaacttttc aatagttgtt 7800

 tgtgagctat gataatcaaa agtcattaaa gtctttttta acaaacattc 7850

 gtgcttactt ttcaacataa ttcccagtta tatacagaaa aagatttcca 7900

 cctgtcacgt atctgcctct tttacctgag caatggtgta gttcttagac 7950

 ctaaggtctg taattgcaat acttttaaag aaagatgttg ctctaagtgc 8000

 tgtttgttag ttatgaaatc agatttttct gcttgttctt aatgctgtgg 8050

 tcaaaccata gcacaaaatc attaaaaata atcagcggca tac 8093

<210> 2049
<211> 248
<212> PRT
<213> Homo sapien

<400> 2049
 Met Ala Ala Glu Leu Glu Phe Ala Gln Ile Ile Ile Ile Val Val
   1               5                  10                  15

 Val Val Thr Val Met Val Val Val Ile Val Cys Leu Leu Asn His
                  20                  25                  30

 Tyr Lys Val Ser Thr Arg Ser Phe Ile Asn Arg Pro Asn Gln Ser
                  35                  40                  45

 Arg Arg Arg Glu Asp Gly Leu Pro Gln Glu Gly Cys Leu Trp Pro
                  50                  55                  60

 Ser Asp Ser Ala Ala Pro Arg Leu Gly Ala Ser Glu Ile Met His
                  65                  70                  75

 Ala Pro Arg Ser Arg Asp Arg Phe Thr Ala Pro Ser Phe Ile Gln
                  80                  85                  90

 Arg Asp Arg Phe Ser Arg Phe Gln Pro Thr Tyr Pro Tyr Val Gln
                  95                 100                 105

 His Glu Ile Asp Leu Pro Pro Thr Ile Ser Leu Ser Asp Gly Glu
                 110                 115                 120

 Glu Pro Pro Pro Tyr Gln Gly Pro Cys Thr Leu Gln Leu Arg Asp
                 125                 130                 135

 Pro Glu Gln Gln Met Glu Leu Asn Arg Glu Ser Val Arg Ala Pro
                 140                 145                 150

 Pro Asn Arg Thr Ile Phe Asp Ser Asp Leu Ile Asp Ile Ala Met
                 155                 160                 165

 Tyr Ser Gly Gly Pro Cys Pro Pro Ser Ser Asn Ser Gly Ile Ser
                 170                 175                 180

 Ala Ser Thr Cys Ser Ser Asn Gly Arg Met Glu Gly Pro Pro Pro
                 185                 190                 195

 Thr Tyr Ser Glu Val Met Gly His His Pro Gly Ala Ser Phe Leu
                 200                 205                 210

 His His Gln Arg Ser Asn Ala His Arg Gly Ser Arg Leu Gln Phe
                 215                 220                 225

 Gln Gln Asn Asn Ala Glu Ser Thr Ile Val Pro Ile Lys Gly Lys
                 230                 235                 240

 Asp Arg Lys Pro Gly Asn Leu Val
                 245

<210> 2050
<211> 3367
<212> DNA
<213> Homo sapien

<400> 2050
 gaggccgagc tcggctgggc ttggcgaggc tgcagcgcgg ccaccggcgg 50

 gagtgcagcg gccactgtac ccagagattc aaaaccccaa acccgggact 100

 tgggggcgct gagccgggcc gggaagcaga gcctggtcgt gaggaacagc 150

 cgcccgttgc tgtctgcccc tttgcggaca gcgtctccct cgactccgct 200

 taggaagtgg tgggggcggc gtggcccccg tcgggaggcg ttcgaacgcc 250

 cgctaggaga gagaaaggat tcccctgtgc ttggagcccg cactcgggcg 300

 cggagggagc ggcggcaggc tctcgctttc ggcaccatgg gctgcacgct 350

 gagcgccgag gacaaggcgg cggtggagcg gagtaagatg atcgaccgca 400

 acctccgtga ggacggcgag aaggcggcgc gcgaggtcaa gctgctgctg 450

 ctcggtgctg gtgaatctgg taaaagtaca attgtgaagc agatgaaaat 500

 tatccatgaa gctggttatt cagaagagga gtgtaaacaa tacaaagcag 550

 tggtctacag taacaccatc cagtcaatta ttgctatcat tagggctatg 600

 gggaggttga agatagactt tggtgactca gcccgggcgg atgatgcacg 650

 ccaactcttt gtgctagctg gagctgctga agaaggcttt atgactgcag 700

 aacttgctgg agttataaag agattgtgga aagatagtgg tgtacaagcc 750

 tgtttcaaca gatcccgaga gtaccagctt aatgattctg cagcatacta 800

 tttgaatgac ttggacagaa tagctcaacc aaattacatc ccgactcaac 850

 aagatgttct cagaactaga gtgaaaacta caggaattgt tgaaacccat 900

 tttactttca aagatcttca ttttaaaatg tttgatgtgg gaggtcagag 950

 atctgagcgg aagaagtgga ttcattgctt cgaaggagtg gcggcgatca 1000

 tcttctgtgt agcactgagt gactacgacc tggttctagc tgaagatgaa 1050

 gaaatgaacc gaatgcatga aagcatgaaa ttgtttgaca gcatatgtaa 1100

 caacaagtgg tttacagata catccattat actttttcta aacaagaagg 1150

 atctttttga agaaaaaatc aaaaagagcc ctctcactat atgctatcaa 1200

 gaatatgcag gatcaaacac atatgaagag gcagctgcat atattcaatg 1250

 tcagtttgaa gacctcaata aaagaaagga cacaaaggaa atatacaccc 1300

 acttcacatg tgccacagat actaagaatg tgcagtttgt ttttgatgct 1350

 gtaacagatg tcatcataaa aaataatcta aaagattgtg gtctctttta 1400

 agttttgcag ttcatggtaa aatgcatttt caaaccaaat gagtacttat 1450

 atatggatct ctgtagacta gagtcttgca gcaacacaga atgtaatata 1500

 aggcaaatgc atctgggact tgaccaaagt tgttctgttt tgttttttta 1550

 actgaaagta acagaaggac ctttcttaaa tgtgacagat ggtcctgcag 1600

 tgtgaaactg aaggacagtg ttaaagctgg gctctagtat attgatgatt 1650

 tctgcataag tgtaaatatg caaatgtatg tatacatgta tttatgactt 1700

 tagttttcga cattattttt aggttttaag agtggcaact taggatttta 1750

 gggtgatggc tttggaaata acataaatat accttgtact gaatgacaga 1800

 ctattactac gtttgccagt tttaaacagc tttatttatg ttcatgtcct 1850

 gtaaattttt aagtacagta attaatatta ggaaacatta cagcccttat 1900

 ctagattata tgtatacttg tattaataaa aatgttattt gtacaaacat 1950

 tgcacagact attttaataa catgatttgt tctttaaatt ttatgtgttt 2000

 tattgaaatg ttcttaagat gaatacacct gcctttggat caactattta 2050

 aacattgtat gcattttgat ttttcctact ttaagaaaat aaaataattt 2100

 aattttacat tagattccac gttagatttg gtttgaaaaa ctaaaatttc 2150

 agatttctga ggatatactg tcttagactt attgtacaca cttagttttt 2200

 attcacttgt tttcactctg aattttaata tttggctgat atgaatgcat 2250

 tgcctcaaag gtgatgtcat cttaattttt attcacttta aataactaca 2300

 tttttgttta taactaagtt tggagggatc ctaagagcat ttttgtgggt 2350

 aaaaaaaaaa cctgtggaca taatgaattt tgagacattg attggtgagg 2400

 cttttatttc ccttgaggag tctcttgtac ctagcataca tgatagctcc 2450

 ttgttgggaa gataacaaga aggatctttg aatactctat tgctgatata 2500

 atgcaagatt taaatttata catataacta atttcaaatg taattatcac 2550

 actatgttaa aattactttt ttcccttaga taattcaaat ttctccactt 2600

 gcttgagatt atatcatttc tttttcaatt atactattat ttctgagaat 2650

 gaaatggacg attacactta gaaaatgagt aatagtgttt aataagtcag 2700

 tgattatatg tgtgctcaaa taagtgttat gtatcagcta gatactgagc 2750

 tttgatagaa taattttctt ttgattattc atgatgtgtc atctctgacc 2800

 ttgtttcagc aaagtaaaca gcactcccca ccccaccctc atttttttac 2850

 tcatcttgga aaaggttagt ctttcagtac acgttactgg taagtagttt 2900

 ccaagttacg tgttgtcact gggttgaagt atatttgtgt gtgtgtgtgt 2950

 gtgtgtgtgt gtgtgtgtgt gtgtgtaacc ataaactata ttcatatctg 3000

 tttcatttgg aggattttct tctttgtaat gtaaagaaat tcaaagttat 3050

 caaagttcct taaatgtgtt agtttagatt ctttatgtgc ctttcatgaa 3100

 agatatgttt tcattaattt tactggtgga cctgtaatat ccacattgtg 3150

 aagctgtgta tgaaattcaa ctataatatg aataaatttg aatcatgaga 3200

 attatgggtt aaaaagccac aaagaagcac atattggtga ccatcattaa 3250

 tgaaatcctg aactttattc tgtgtaattg tgttaataaa tcctaataaa 3300

 tttaaatttt taaaatttta caaacaaaaa aaaaaaaaaa aaaaaaaaag 3350

 aaaaaaaaaa aaaaaaa 3367

<210> 2051
<211> 354
<212> PRT
<213> Homo sapien

<400> 2051
 Met Gly Cys Thr Leu Ser Ala Glu Asp Lys Ala Ala Val Glu Arg
   1               5                  10                  15

 Ser Lys Met Ile Asp Arg Asn Leu Arg Glu Asp Gly Glu Lys Ala
                  20                  25                  30

 Ala Arg Glu Val Lys Leu Leu Leu Leu Gly Ala Gly Glu Ser Gly
                  35                  40                  45

 Lys Ser Thr Ile Val Lys Gln Met Lys Ile Ile His Glu Ala Gly
                  50                  55                  60

 Tyr Ser Glu Glu Glu Cys Lys Gln Tyr Lys Ala Val Val Tyr Ser
                  65                  70                  75

 Asn Thr Ile Gln Ser Ile Ile Ala Ile Ile Arg Ala Met Gly Arg
                  80                  85                  90

 Leu Lys Ile Asp Phe Gly Asp Ser Ala Arg Ala Asp Asp Ala Arg
                  95                 100                 105

 Gln Leu Phe Val Leu Ala Gly Ala Ala Glu Glu Gly Phe Met Thr
                 110                 115                 120

 Ala Glu Leu Ala Gly Val Ile Lys Arg Leu Trp Lys Asp Ser Gly
                 125                 130                 135

 Val Gln Ala Cys Phe Asn Arg Ser Arg Glu Tyr Gln Leu Asn Asp
                 140                 145                 150

 Ser Ala Ala Tyr Tyr Leu Asn Asp Leu Asp Arg Ile Ala Gln Pro
                 155                 160                 165

 Asn Tyr Ile Pro Thr Gln Gln Asp Val Leu Arg Thr Arg Val Lys
                 170                 175                 180

 Thr Thr Gly Ile Val Glu Thr His Phe Thr Phe Lys Asp Leu His
                 185                 190                 195

 Phe Lys Met Phe Asp Val Gly Gly Gln Arg Ser Glu Arg Lys Lys
                 200                 205                 210

 Trp Ile His Cys Phe Glu Gly Val Ala Ala Ile Ile Phe Cys Val
                 215                 220                 225

 Ala Leu Ser Asp Tyr Asp Leu Val Leu Ala Glu Asp Glu Glu Met
                 230                 235                 240

 Asn Arg Met His Glu Ser Met Lys Leu Phe Asp Ser Ile Cys Asn
                 245                 250                 255

 Asn Lys Trp Phe Thr Asp Thr Ser Ile Ile Leu Phe Leu Asn Lys
                 260                 265                 270

 Lys Asp Leu Phe Glu Glu Lys Ile Lys Lys Ser Pro Leu Thr Ile
                 275                 280                 285

 Cys Tyr Gln Glu Tyr Ala Gly Ser Asn Thr Tyr Glu Glu Ala Ala
                 290                 295                 300

 Ala Tyr Ile Gln Cys Gln Phe Glu Asp Leu Asn Lys Arg Lys Asp
                 305                 310                 315

 Thr Lys Glu Ile Tyr Thr His Phe Thr Cys Ala Thr Asp Thr Lys
                 320                 325                 330

 Asn Val Gln Phe Val Phe Asp Ala Val Thr Asp Val Ile Ile Lys
                 335                 340                 345

 Asn Asn Leu Lys Asp Cys Gly Leu Phe
                 350

<210> 2052
<211> 2140
<212> DNA
<213> Homo sapien

<400> 2052
 ggagctccag gcgcacatcc gcagtcagcc acctcgcgcg cgcctccagg 50

 agcaaggatg gagaggctgg tgatcaggat gcccttctgt catctgtcta 100

 cctacagcct ggtttgggtc atggcagcag tggtgctgtg cacagcacaa 150

 gtgcaagtgg tgacccagga tgaaagagag cagctgtaca cacctgcttc 200

 cttaaaatgc tctctgcaaa atgcccagga agccctcatt gtgacatggc 250

 agaaaaagaa agctgtaagc ccagaaaaca tggtcacctt cagcgagaac 300

 catggggtgg tgatccagcc tgcctataag gacaagataa acattaccca 350

 gctgggactc caaaactcaa ccatcacctt ctggaatatc accctggagg 400

 atgaagggtg ttacatgtgt ctcttcaata cctttggttt tgggaagatc 450

 tcaggaacgg cctgcctcac cgtctatgta cagcccatag tatcccttca 500

 ctacaaattc tctgaagacc acctaaatat cacttgctct gccactgccc 550

 gcccagcccc catggtcttc tggaaggtcc ctcggtcagg gattgaaaat 600

 agtacagtga ctctgtctca cccaaatggg accacgtctg ttaccagcat 650

 cctccatatc aaagacccta agaatcaggt ggggaaggag gtgatctgcc 700

 aggtgctgca cctggggact gtgaccgact ttaagcaaac cgtcaacaaa 750

 ggctattggt tttcagttcc gctattgcta agcattgttt ccctggtaat 800

 tcttctcgtc ctaatctcaa tcttactgta ctggaaacgt caccggaatc 850

 aggaccgaga gccctaacta agtcacacag caccctgaaa gtgattccct 900

 ggtctacttg aatttgacac aagagaaaag caggaggaaa aggggccatt 950

 ctccaaagga cctgaaagag caaaagaggt gggagcgaaa gccttaagga 1000

 tcccacgact ttttactgcc atctgagcta ctcagtgttt gaatcccaag 1050

 aggaagtcag tttacctctc aggtctgttg taggacttga ttttgtaaag 1100

 caatgccatg ttatgtggtt gaaagggcac tggacttagt atcaggagca 1150

 ctgagctcac agactgactt gggctcctac tggtggggac ctctgttagt 1200

 cactttacct catccaaagt ataaaggaat tggaccaaat aatttaccac 1250

 atagctctaa aacttaattt aaaatgtaat tccagaaaaa aaaagggaat 1300

 aagcaaaggg ggaagaattg aaagagagag agaagaaaga atacagagag 1350

 cttacctttt gcctttctgt tgatgttaca tctcttcttc ctatgttctt 1400

 aggtctatga gtctgtttcc ccatcatttg gtatctagtc cagttcctgc 1450

 ttactgcttt gctaatagct ggccttgcta gaatccttgg ttcactgctg 1500

 ttcttcatgt gcttctatga gatttactcc aacacaaata ggactgaatt 1550

 tattgtgaag taacattggc aatcttaact tattcattta acttattttt 1600

 atagctagat aaatattgtt agtcttagac aatagctcac attttttgag 1650

 aagcatgccc tccctgtcca tttgtcttat aacatgaccc agccctattt 1700

 tacgtcattc taaattcagc ctcatataat gaaaatacat tatgaaaaca 1750

 gatgtttagg agatttcctg tatagcagtc agccaattca tatgctttgt 1800

 ctctgctggc ttctttttcc atgcgttaac ttttcccaat agcagaggag 1850

 gcaaatatga gcatacaatc cctttgttct aaagatattg ttccagctag 1900

 tggaatgatg ttgaatcttt aataaccata attagttgct ttttcagtat 1950

 cttctgcttt gtctgtgtct atccagtggc ctaggaatta aagtgtaagt 2000

 tgtttttgct gttaaattgg atatttatat atatatatat agcaagattt 2050

 tcatgtgtta tttaattctg tattgtttct tatatttgta gtaaaatatt 2100

 gaacaattaa aagtgttgac tccaaaaaaa aaaaaaaaaa 2140

<210> 2053
<211> 269
<212> PRT
<213> Homo sapien

<400> 2053
 Met Glu Arg Leu Val Ile Arg Met Pro Phe Cys His Leu Ser Thr
   1               5                  10                  15

 Tyr Ser Leu Val Trp Val Met Ala Ala Val Val Leu Cys Thr Ala
                  20                  25                  30

 Gln Val Gln Val Val Thr Gln Asp Glu Arg Glu Gln Leu Tyr Thr
                  35                  40                  45

 Pro Ala Ser Leu Lys Cys Ser Leu Gln Asn Ala Gln Glu Ala Leu
                  50                  55                  60

 Ile Val Thr Trp Gln Lys Lys Lys Ala Val Ser Pro Glu Asn Met
                  65                  70                  75

 Val Thr Phe Ser Glu Asn His Gly Val Val Ile Gln Pro Ala Tyr
                  80                  85                  90

 Lys Asp Lys Ile Asn Ile Thr Gln Leu Gly Leu Gln Asn Ser Thr
                  95                 100                 105

 Ile Thr Phe Trp Asn Ile Thr Leu Glu Asp Glu Gly Cys Tyr Met
                 110                 115                 120

 Cys Leu Phe Asn Thr Phe Gly Phe Gly Lys Ile Ser Gly Thr Ala
                 125                 130                 135

 Cys Leu Thr Val Tyr Val Gln Pro Ile Val Ser Leu His Tyr Lys
                 140                 145                 150

 Phe Ser Glu Asp His Leu Asn Ile Thr Cys Ser Ala Thr Ala Arg
                 155                 160                 165

 Pro Ala Pro Met Val Phe Trp Lys Val Pro Arg Ser Gly Ile Glu
                 170                 175                 180

 Asn Ser Thr Val Thr Leu Ser His Pro Asn Gly Thr Thr Ser Val
                 185                 190                 195

 Thr Ser Ile Leu His Ile Lys Asp Pro Lys Asn Gln Val Gly Lys
                 200                 205                 210

 Glu Val Ile Cys Gln Val Leu His Leu Gly Thr Val Thr Asp Phe
                 215                 220                 225

 Lys Gln Thr Val Asn Lys Gly Tyr Trp Phe Ser Val Pro Leu Leu
                 230                 235                 240

 Leu Ser Ile Val Ser Leu Val Ile Leu Leu Val Leu Ile Ser Ile
                 245                 250                 255

 Leu Leu Tyr Trp Lys Arg His Arg Asn Gln Asp Arg Glu Pro
                 260                 265

<210> 2054
<211> 2140
<212> DNA
<213> Homo sapien

<400> 2054
 ggagctccag gcgcacatcc gcagtcagcc acctcgcgcg cgcctccagg 50

 agcaaggatg gagaggctgg tgatcaggat gcccttctgt catctgtcta 100

 cctacagcct ggtttgggtc atggcagcag tggtgctgtg cacagcacaa 150

 gtgcaagtgg tgacccagga tgaaagagag cagctgtaca cacctgcttc 200

 cttaaaatgc tctctgcaaa atgcccagga agccctcatt gtgacatggc 250

 agaaaaagaa agctgtaagc ccagaaaaca tggtcacctt cagcgagaac 300

 catggggtgg tgatccagcc tgcctataag gacaagataa acattaccca 350

 gctgggactc caaaactcaa ccatcacctt ctggaatatc accctggagg 400

 atgaagggtg ttacatgtgt ctcttcaata cctttggttt tgggaagatc 450

 tcaggaacgg cctgcctcac cgtctatgta cagcccatag tatcccttca 500

 ctacaaattc tctgaagacc acctaaatat cacttgctct gccactgccc 550

 gcccagcccc catggtcttc tggaaggtcc ctcggtcagg gattgaaaat 600

 agtacagtga ctctgtctca cccaaatggg accacgtctg ttaccagcat 650

 cctccatatc aaagacccta agaatcaggt ggggaaggag gtgatctgcc 700

 aggtgctgca cctggggact gtgaccgact ttaagcaaac cgtcaacaaa 750

 ggctattggt tttcagttcc gctattgcta agcattgttt ccctggtaat 800

 tcttctcgtc ctaatctcaa tcttactgta ctggaaacgt caccggaatc 850

 aggaccgaga gccctaacta agtcacacag caccctgaaa gtgattccct 900

 ggtctacttg aatttgacac aagagaaaag caggaggaaa aggggccatt 950

 ctccaaagga cctgaaagag caaaagaggt gggagcgaaa gccttaagga 1000

 tcccacgact ttttactgcc atctgagcta ctcagtgttt gaatcccaag 1050

 aggaagtcag tttacctctc aggtctgttg taggacttga ttttgtaaag 1100

 caatgccatg ttatgtggtt gaaagggcac tggacttagt atcaggagca 1150

 ctgagctcac agactgactt gggctcctac tggtggggac ctctgttagt 1200

 cactttacct catccaaagt ataaaggaat tggaccaaat aatttaccac 1250

 atagctctaa aacttaattt aaaatgtaat tccagaaaaa aaaagggaat 1300

 aagcaaaggg ggaagaattg aaagagagag agaagaaaga atacagagag 1350

 cttacctttt gcctttctgt tgatgttaca tctcttcttc ctatgttctt 1400

 aggtctatga gtctgtttcc ccatcatttg gtatctagtc cagttcctgc 1450

 ttactgcttt gctaatagct ggccttgcta gaatccttgg ttcactgctg 1500

 ttcttcatgt gcttctatga gatttactcc aacacaaata ggactgaatt 1550

 tattgtgaag taacattggc aatcttaact tattcattta acttattttt 1600

 atagctagat aaatattgtt agtcttagac aatagctcac attttttgag 1650

 aagcatgccc tccctgtcca tttgtcttat aacatgaccc agccctattt 1700

 tacgtcattc taaattcagc ctcatataat gaaaatacat tatgaaaaca 1750

 gatgtttagg agatttcctg tatagcagtc agccaattca tatgctttgt 1800

 ctctgctggc ttctttttcc atgcgttaac ttttcccaat agcagaggag 1850

 gcaaatatga gcatacaatc cctttgttct aaagatattg ttccagctag 1900

 tggaatgatg ttgaatcttt aataaccata attagttgct ttttcagtat 1950

 cttctgcttt gtctgtgtct atccagtggc ctaggaatta aagtgtaagt 2000

 tgtttttgct gttaaattgg atatttatat atatatatat agcaagattt 2050

 tcatgtgtta tttaattctg tattgtttct tatatttgta gtaaaatatt 2100

 gaacaattaa aagtgttgac tccaaaaaaa aaaaaaaaaa 2140

<210> 2055
<211> 269
<212> PRT
<213> Homo sapien

<400> 2055
 Met Glu Arg Leu Val Ile Arg Met Pro Phe Cys His Leu Ser Thr
   1               5                  10                  15

 Tyr Ser Leu Val Trp Val Met Ala Ala Val Val Leu Cys Thr Ala
                  20                  25                  30

 Gln Val Gln Val Val Thr Gln Asp Glu Arg Glu Gln Leu Tyr Thr
                  35                  40                  45

 Pro Ala Ser Leu Lys Cys Ser Leu Gln Asn Ala Gln Glu Ala Leu
                  50                  55                  60

 Ile Val Thr Trp Gln Lys Lys Lys Ala Val Ser Pro Glu Asn Met
                  65                  70                  75

 Val Thr Phe Ser Glu Asn His Gly Val Val Ile Gln Pro Ala Tyr
                  80                  85                  90

 Lys Asp Lys Ile Asn Ile Thr Gln Leu Gly Leu Gln Asn Ser Thr
                  95                 100                 105

 Ile Thr Phe Trp Asn Ile Thr Leu Glu Asp Glu Gly Cys Tyr Met
                 110                 115                 120

 Cys Leu Phe Asn Thr Phe Gly Phe Gly Lys Ile Ser Gly Thr Ala
                 125                 130                 135

 Cys Leu Thr Val Tyr Val Gln Pro Ile Val Ser Leu His Tyr Lys
                 140                 145                 150

 Phe Ser Glu Asp His Leu Asn Ile Thr Cys Ser Ala Thr Ala Arg
                 155                 160                 165

 Pro Ala Pro Met Val Phe Trp Lys Val Pro Arg Ser Gly Ile Glu
                 170                 175                 180

 Asn Ser Thr Val Thr Leu Ser His Pro Asn Gly Thr Thr Ser Val
                 185                 190                 195

 Thr Ser Ile Leu His Ile Lys Asp Pro Lys Asn Gln Val Gly Lys
                 200                 205                 210

 Glu Val Ile Cys Gln Val Leu His Leu Gly Thr Val Thr Asp Phe
                 215                 220                 225

 Lys Gln Thr Val Asn Lys Gly Tyr Trp Phe Ser Val Pro Leu Leu
                 230                 235                 240

 Leu Ser Ile Val Ser Leu Val Ile Leu Leu Val Leu Ile Ser Ile
                 245                 250                 255

 Leu Leu Tyr Trp Lys Arg His Arg Asn Gln Asp Arg Glu Pro
                 260                 265

<210> 2056
<211> 1408
<212> DNA
<213> Homo sapien

<400> 2056
 cgggaacgcc gctcttcgcc tctcagcggc ggcttgtcct ttgttccgga 50

 cgcccgctcc tcagccctgc gtcctggggt cgctgctgca tcccgcacgc 100

 ctccaccggc tgcagaccca tggccgagcg cggggaactc gacttgaccg 150

 gcgccaaaca gaacacagga gtgtggctag tcaaggttcc taaatatttg 200

 tcacagcaat gggctaaagc ctctggaaga ggtgaagttg ggaaactgcg 250

 gattgccaag actcaaggaa ggactgaggt gtcatttact ttgaatgagg 300

 atcttgcaaa tattcatgat attggtggaa aaccagcttc agtcagtgct 350

 cctagagaac atccatttgt cttgcaaagt gttggaggac agacattaac 400

 agtatttact gagagctcat cagataagct gtcattggaa ggaatagtgg 450

 tacaaagagc tgaatgccga ccagctgcca gtgaaaacta catgcgatta 500

 aaaagattgc aaatagaaga gtcttccaaa ccagtgaggc tatcacaaca 550

 gctggacaaa gttgtaacaa ccaattacaa acctgttgct aatcatcaat 600

 acaatatcga atatgaaagg aaaaagaaag aagacggaaa gcgagctcga 650

 gctgataaac aacatgtttt agacatgcta ttttcagcct ttgagaaaca 700

 tcaatactat aatcttaagg acttggtgga catcacaaaa caacctgtgg 750

 tgtacctgaa ggaaatctta aaagaaattg gtgttcagaa tgtaaaaggg 800

 atccacaaaa acacatggga gctgaagcca gagtacagac actatcaagg 850

 agaagaaaag agtgactaag aagactccta gccagcatgc tagtgaaagg 900

 ctagcagcga tgctatgcaa aaggcgctga tactggaagg cttgaacacc 950

 gtatgtttaa taggggttaa gtgacagtac tttgatttct ctcggtaaat 1000

 tttttaaacc tgtaaggctt gtaaagtttc ttaactgttt ttttgaggag 1050

 aaagaacaga tttatttata gacttaactt gtattaaacc agattattca 1100

 cagtaggaat aggggttgga ggattaagag ggtttttctt aaatattagc 1150

 ttttaatgtg tacaattagg aaattttttt aagtgaggac tctctaccct 1200

 tgccgtatct aaggagctga ggtaatacag atccaaggag aattgtatag 1250

 caagaaaaaa acagtcaact acagaaactc ttaaaaggaa taaaaaccca 1300

 aagttcctta ttttgaaatt gtcaaagaac aaacggtgtt tttcttttaa 1350

 acaggtgatc acgtttcttt tcatactcaa cgttaataaa aggagagagt 1400

 ttgtagtg 1408

<210> 2057
<211> 249
<212> PRT
<213> Homo sapien

<400> 2057
 Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn
   1               5                  10                  15

 Thr Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln
                  20                  25                  30

 Trp Ala Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile
                  35                  40                  45

 Ala Lys Thr Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu
                  50                  55                  60

 Asp Leu Ala Asn Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val
                  65                  70                  75

 Ser Ala Pro Arg Glu His Pro Phe Val Leu Gln Ser Val Gly Gly
                  80                  85                  90

 Gln Thr Leu Thr Val Phe Thr Glu Ser Ser Ser Asp Lys Leu Ser
                  95                 100                 105

 Leu Glu Gly Ile Val Val Gln Arg Ala Glu Cys Arg Pro Ala Ala
                 110                 115                 120

 Ser Glu Asn Tyr Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser
                 125                 130                 135

 Ser Lys Pro Val Arg Leu Ser Gln Gln Leu Asp Lys Val Val Thr
                 140                 145                 150

 Thr Asn Tyr Lys Pro Val Ala Asn His Gln Tyr Asn Ile Glu Tyr
                 155                 160                 165

 Glu Arg Lys Lys Lys Glu Asp Gly Lys Arg Ala Arg Ala Asp Lys
                 170                 175                 180

 Gln His Val Leu Asp Met Leu Phe Ser Ala Phe Glu Lys His Gln
                 185                 190                 195

 Tyr Tyr Asn Leu Lys Asp Leu Val Asp Ile Thr Lys Gln Pro Val
                 200                 205                 210

 Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile Gly Val Gln Asn Val
                 215                 220                 225

 Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys Pro Glu Tyr Arg
                 230                 235                 240

 His Tyr Gln Gly Glu Glu Lys Ser Asp
                 245

<210> 2058
<211> 2365
<212> DNA
<213> Homo sapien

<400> 2058
 tcccagcctt cccatccccc caccgaaagc aaatcattca acgacccccg 50

 accctccgac ggcaggagcc ccccgacctc ccaggcggac cgcccttccc 100

 tccccgcgcg ggttccgggc ccggcgagag ggcgcgacga cagccgaggc 150

 catggaggtg acggcggacc agccgcgctg ggtgagccac caccaccccg 200

 ccgtgctcaa cgggcagcac ccggacacgc accacccggg cctcagccac 250

 tcctacatgg acgcggcgca gtacccgctg ccggaggagg tggatgtgct 300

 ttttaacatc gacggtcaag gcaaccacgt cccgccctac tacggaaact 350

 cggtcagggc cacggtgcag aggtaccctc cgacccacca cgggagccag 400

 gtgtgccgcc cgcctctgct tcatggatcc ctaccctggc tggacggcgg 450

 caaagccctg ggcagccacc acaccgcctc cccctggaat ctcagcccct 500

 tctccaagac gtccatccac cacggctccc cggggcccct ctccgtctac 550

 cccccggcct cgtcctcctc cttgtcgggg ggccacgcca gcccgcacct 600

 cttcaccttc ccgcccaccc cgccgaagga cgtctccccg gacccatcgc 650

 tgtccacccc aggctcggcc ggctcggccc ggcaggacga gaaagagtgc 700

 ctcaagtacc aggtgcccct gcccgacagc atgaagctgg agtcgtccca 750

 ctcccgtggc agcatgaccg ccctgggtgg agcctcctcg tcgacccacc 800

 accccatcac cacctacccg ccctacgtgc ccgagtacag ctccggactc 850

 ttccccccca gcagcctgct gggcggctcc cccaccggct tcggatgcaa 900

 gtccaggccc aaggcccggt ccagcacagg cagggagtgt gtgaactgtg 950

 gggcaacctc gaccccactg tggcggcgag atggcacggg acactacctg 1000

 tgcaacgcct gcgggctcta tcacaaaatg aacggacaga accggcccct 1050

 cattaagccc aagcgaaggc tgtctgcagc caggagagca gggacgtcct 1100

 gtgcgaactg tcagaccacc acaaccacac tctggaggag gaatgccaat 1150

 ggggaccctg tctgcaatgc ctgtgggctc tactacaagc ttcacaatat 1200

 taacagaccc ctgactatga agaaggaagg catccagacc agaaaccgaa 1250

 aaatgtctag caaatccaaa aagtgcaaaa aagtgcatga ctcactggag 1300

 gacttcccca agaacagctc gtttaacccg gccgccctct ccagacacat 1350

 gtcctccctg agccacatct cgcccttcag ccactccagc cacatgctga 1400

 ccacgcccac gccgatgcac ccgccatcca gcctgtcctt tggaccacac 1450

 cacccctcca gcatggtcac cgccatgggt tagagccctg ctcgatgctc 1500

 acagggcccc cagcgagagt ccctgcagtc cctttcgact tgcatttttg 1550

 caggagcagt atcatgaagc ctaaacgcga tggatatatg tttttgaagg 1600

 cagaaagcaa aattatgttt gccactttgc aaaggagctc actgtggtgt 1650

 ctgtgttcca accactgaat ctggacccca tctgtgaata agccattctg 1700

 actcatatcc cctatttaac agggtctcta gtgctgtgaa aaaaaaaaat 1750

 cctgaacatt gcatataact tatattgtaa gaaatactgt acaatgactt 1800

 tattgcatct gggtagctgt aaggcatgaa ggatgccaag aagtttaagg 1850

 aatatgggag aaatagtgtg gaaattaaga agaaactagg tctgatattc 1900

 aaatggacaa actgccagtt ttgtttcctt tcactggcca cagttgtttg 1950

 atgcattaaa agaaaataaa aaaaagaaaa aagagaaaag aaaaaaaaag 2000

 aaaaaagttg taggcgaatc atttgttcaa agctgttggc cctctgcaaa 2050

 ggaaatacca gttctgggca atcagtgtta ccgttcacca gttgccattg 2100

 agggtttcag agagcctttt tctaggccta catgctttgt gaacaagtcc 2150

 ctgtaattgt tgtttgtatg tataattcaa agcaccaaaa taagaaaaga 2200

 tgtagattta tttcatcata ttatacagac cgaactgttg tataaattta 2250

 tttactgcta gtcttaagaa ctgctttctt tcgtttgttt gtttcaatat 2300

 tttccttctc tctcaatttt cggttgaata aactagatta cattcagttg 2350

 gcaaaaaaaa aaaaa 2365

<210> 2059
<211> 443
<212> PRT
<213> Homo sapien

<400> 2059
 Met Glu Val Thr Ala Asp Gln Pro Arg Trp Val Ser His His His
   1               5                  10                  15

 Pro Ala Val Leu Asn Gly Gln His Pro Asp Thr His His Pro Gly
                  20                  25                  30

 Leu Ser His Ser Tyr Met Asp Ala Ala Gln Tyr Pro Leu Pro Glu
                  35                  40                  45

 Glu Val Asp Val Leu Phe Asn Ile Asp Gly Gln Gly Asn His Val
                  50                  55                  60

 Pro Pro Tyr Tyr Gly Asn Ser Val Arg Ala Thr Val Gln Arg Tyr
                  65                  70                  75

 Pro Pro Thr His His Gly Ser Gln Val Cys Arg Pro Pro Leu Leu
                  80                  85                  90

 His Gly Ser Leu Pro Trp Leu Asp Gly Gly Lys Ala Leu Gly Ser
                  95                 100                 105

 His His Thr Ala Ser Pro Trp Asn Leu Ser Pro Phe Ser Lys Thr
                 110                 115                 120

 Ser Ile His His Gly Ser Pro Gly Pro Leu Ser Val Tyr Pro Pro
                 125                 130                 135

 Ala Ser Ser Ser Ser Leu Ser Gly Gly His Ala Ser Pro His Leu
                 140                 145                 150

 Phe Thr Phe Pro Pro Thr Pro Pro Lys Asp Val Ser Pro Asp Pro
                 155                 160                 165

 Ser Leu Ser Thr Pro Gly Ser Ala Gly Ser Ala Arg Gln Asp Glu
                 170                 175                 180

 Lys Glu Cys Leu Lys Tyr Gln Val Pro Leu Pro Asp Ser Met Lys
                 185                 190                 195

 Leu Glu Ser Ser His Ser Arg Gly Ser Met Thr Ala Leu Gly Gly
                 200                 205                 210

 Ala Ser Ser Ser Thr His His Pro Ile Thr Thr Tyr Pro Pro Tyr
                 215                 220                 225

 Val Pro Glu Tyr Ser Ser Gly Leu Phe Pro Pro Ser Ser Leu Leu
                 230                 235                 240

 Gly Gly Ser Pro Thr Gly Phe Gly Cys Lys Ser Arg Pro Lys Ala
                 245                 250                 255

 Arg Ser Ser Thr Gly Arg Glu Cys Val Asn Cys Gly Ala Thr Ser
                 260                 265                 270

 Thr Pro Leu Trp Arg Arg Asp Gly Thr Gly His Tyr Leu Cys Asn
                 275                 280                 285

 Ala Cys Gly Leu Tyr His Lys Met Asn Gly Gln Asn Arg Pro Leu
                 290                 295                 300

 Ile Lys Pro Lys Arg Arg Leu Ser Ala Ala Arg Arg Ala Gly Thr
                 305                 310                 315

 Ser Cys Ala Asn Cys Gln Thr Thr Thr Thr Thr Leu Trp Arg Arg
                 320                 325                 330

 Asn Ala Asn Gly Asp Pro Val Cys Asn Ala Cys Gly Leu Tyr Tyr
                 335                 340                 345

 Lys Leu His Asn Ile Asn Arg Pro Leu Thr Met Lys Lys Glu Gly
                 350                 355                 360

 Ile Gln Thr Arg Asn Arg Lys Met Ser Ser Lys Ser Lys Lys Cys
                 365                 370                 375

 Lys Lys Val His Asp Ser Leu Glu Asp Phe Pro Lys Asn Ser Ser
                 380                 385                 390

 Phe Asn Pro Ala Ala Leu Ser Arg His Met Ser Ser Leu Ser His
                 395                 400                 405

 Ile Ser Pro Phe Ser His Ser Ser His Met Leu Thr Thr Pro Thr
                 410                 415                 420

 Pro Met His Pro Pro Ser Ser Leu Ser Phe Gly Pro His His Pro
                 425                 430                 435

 Ser Ser Met Val Thr Ala Met Gly
                 440

<210> 2060
<211> 3042
<212> DNA
<213> Homo sapien

<400> 2060
 ggagccgcgt gccctccgcc ccggggtgcc cattgcgcag agcgtggcct 50

 ggagacccgc gagccgggga aggtcgccgt ggagtcccga ccagaggccg 100

 gggttggggt cggtgcagac cgagggctgg tttccttgac tgtgggagaa 150

 acgccgggag ccggagtgac ccgaggaggg actccgcctc cgagcggctg 200

 aggaccccgg tgcagaggag cctggctcgc agaattgcag agtcgtcgcc 250

 cctttttaca acctggtccc gttttattct gccataccca gtttttggat 300

 ttttgtcttc cccttcttct cttgctaaac gacccctcca agataatttt 350

 taaaaaacct tctcctttgc tcacctttgc ttcccagcct tcccatcccc 400

 ccaccgaaag caaatcattc aacgaccccc gacctccgac ggcaggagcc 450

 ccccgacctc ccaggcggac cgccctccct ccccgcgcgc gggttccggg 500

 cccggcgaga gggcgcgagc acagccgagg ccatggaggt gacggcggac 550

 cagccgcgct gggtgagcca ccaccacccc gccgtgctca acgggcagca 600

 cccggacacg caccacccgg gcctcagcca ctcctacatg gacgcggcgc 650

 agtacccgct gccggaggag gtggatgtgc tttttaacat cgacggtcaa 700

 ggcaaccacg tcccgcccta ctacggaaac tcggtcaggg ccacggtgca 750

 gaggtaccct ccgacccacc acgggagcca ggtgtgccgc ccgcctctgc 800

 ttcatggatc cctaccctgg ctggacggcg gcaaagccct gggcagccac 850

 cacaccgcct ccccctggaa tctcagcccc ttctccaaga cgtccatcca 900

 ccacggctcc ccggggcccc tctccgtcta ccccccggcc tcgtcctcct 950

 ccttgtcggg gggccacgcc agcccgcacc tcttcacctt cccgcccacc 1000

 ccgccgaagg acgtctcccc ggacccatcg ctgtccaccc caggctcggc 1050

 cggctcggcc cggcaggacg agaaagagtg cctcaagtac caggtgcccc 1100

 tgcccgacag catgaagctg gagtcgtccc actcccgtgg cagcatgacc 1150

 gccctgggtg gagcctcctc gtcgacccac caccccatca ccacctaccc 1200

 gccctacgtg cccgagtaca gctccggact cttccccccc agcagcctgc 1250

 tgggcggctc ccccaccggc ttcggatgca agtccaggcc caaggcccgg 1300

 tccagcacag aaggcaggga gtgtgtgaac tgtggggcaa cctcgacccc 1350

 actgtggcgg cgagatggca cgggacacta cctgtgcaac gcctgcgggc 1400

 tctatcacaa aatgaacgga cagaaccggc ccctcattaa gcccaagcga 1450

 aggctgtctg cagccaggag agcagggacg tcctgtgcga actgtcagac 1500

 caccacaacc acactctgga ggaggaatgc caatggggac cctgtctgca 1550

 atgcctgtgg gctctactac aagcttcaca atattaacag acccctgact 1600

 atgaagaagg aaggcatcca gaccagaaac cgaaaaatgt ctagcaaatc 1650

 caaaaagtgc aaaaaagtgc atgactcact ggaggacttc cccaagaaca 1700

 gctcgtttaa cccggccgcc ctctccagac acatgtcctc cctgagccac 1750

 atctcgccct tcagccactc cagccacatg ctgaccacgc ccacgccgat 1800

 gcacccgcca tccagcctgt cctttggacc acaccacccc tccagcatgg 1850

 tcaccgccat gggttagagc cctgctcgat gctcacaggg cccccagcga 1900

 gagtccctgc agtccctttc gacttgcatt tttgcaggag cagtatcatg 1950

 aagcctaaac gcgatggata tatgtttttg aaggcagaaa gcaaaattat 2000

 gtttgccact ttgcaaagga gctcactgtg gtgtctgtgt tccaaccact 2050

 gaatctggac cccatctgtg aataagccat tctgactcat atcccctatt 2100

 taacagggtc tctagtgctg tgaaaaaaaa aaatgctgaa cattgcatat 2150

 aacttatatt gtaagaaata ctgtacaatg actttattgc atctgggtag 2200

 ctgtaaggca tgaaggatgc caagaagttt aaggaatatg ggagaaatag 2250

 tgtggaaatt aagaagaaac taggtctgat attcaaatgg acaaactgcc 2300

 agttttgttt cctttcactg gccacagttg tttgatgcat taaaagaaaa 2350

 taaaaaaaag aaaaaagaga aaagaaaaaa aaaggaaaaa gttgtaggcg 2400

 aatcatttgt tcaaagctgt tggcctctgc aaaggaaata ccagttctgg 2450

 gcaatcagtg ttaccgttca ccagttgcca ttgagggttt cagagagcct 2500

 ttttctaggc ctacatgctt tgtgaacaag tccctgtaat tgttgtttgt 2550

 atgtataatt caaagcacca aaataagaaa agatgtagat ttatttcatc 2600

 atattataca gaccgaactg ttgtataaat ttatttactg ctagtcttaa 2650

 gaactgcttt ctttcgtttg tttgtttcaa tattttcctt ctctctcaat 2700

 ttttggttga ataaactaga ttacattcag ttggcctaag gtggttgtgc 2750

 tcggagggtt tcttgtttct tttccatttt gtttttggat gatatttatt 2800

 aaatagcttc taagagtccg gcggcatctg tcttgtccct attcctgcag 2850

 cctgtgctga gggtagcagt gtatgagcta ccagcgtgca tgtcagcgac 2900

 cctggcccga caggccacgt cctgcaatcg gcccggctgc ctcttcgccc 2950

 tgtcgtgttc tgtgttagtg atcactgcct ttaatacagt ctgttggaat 3000

 aatattataa gcataataat aaagtgaaaa tattttaaaa ct 3042

<210> 2061
<211> 621
<212> PRT
<213> Homo sapien

<400> 2061
 Ser Arg Val Pro Ser Ala Pro Gly Cys Pro Leu Arg Arg Ala Trp
   1               5                  10                  15

 Pro Gly Asp Pro Arg Ala Gly Glu Gly Arg Arg Gly Val Pro Thr
                  20                  25                  30

 Arg Gly Arg Gly Trp Gly Arg Cys Arg Pro Arg Ala Gly Phe Leu
                  35                  40                  45

 Asp Cys Gly Arg Asn Ala Gly Ser Arg Ser Asp Pro Arg Arg Asp
                  50                  55                  60

 Ser Ala Ser Glu Arg Leu Arg Thr Pro Val Gln Arg Ser Leu Ala
                  65                  70                  75

 Arg Arg Ile Ala Glu Ser Ser Pro Leu Phe Thr Thr Trp Ser Arg
                  80                  85                  90

 Phe Ile Leu Pro Tyr Pro Val Phe Gly Phe Leu Ser Ser Pro Ser
                  95                 100                 105

 Ser Leu Ala Lys Arg Pro Leu Gln Asp Asn Phe Leu Lys Asn Leu
                 110                 115                 120

 Leu Leu Cys Ser Pro Leu Leu Pro Ser Leu Pro Ile Pro Pro Pro
                 125                 130                 135

 Lys Ala Asn His Ser Thr Thr Pro Asp Leu Arg Arg Gln Glu Pro
                 140                 145                 150

 Pro Asp Leu Pro Gly Gly Pro Pro Ser Leu Pro Ala Arg Gly Phe
                 155                 160                 165

 Arg Ala Arg Arg Glu Gly Ala Ser Thr Ala Glu Ala Met Glu Val
                 170                 175                 180

 Thr Ala Asp Gln Pro Arg Trp Val Ser His His His Pro Ala Val
                 185                 190                 195

 Leu Asn Gly Gln His Pro Asp Thr His His Pro Gly Leu Ser His
                 200                 205                 210

 Ser Tyr Met Asp Ala Ala Gln Tyr Pro Leu Pro Glu Glu Val Asp
                 215                 220                 225

 Val Leu Phe Asn Ile Asp Gly Gln Gly Asn His Val Pro Pro Tyr
                 230                 235                 240

 Tyr Gly Asn Ser Val Arg Ala Thr Val Gln Arg Tyr Pro Pro Thr
                 245                 250                 255

 His His Gly Ser Gln Val Cys Arg Pro Pro Leu Leu His Gly Ser
                 260                 265                 270

 Leu Pro Trp Leu Asp Gly Gly Lys Ala Leu Gly Ser His His Thr
                 275                 280                 285

 Ala Ser Pro Trp Asn Leu Ser Pro Phe Ser Lys Thr Ser Ile His
                 290                 295                 300

 His Gly Ser Pro Gly Pro Leu Ser Val Tyr Pro Pro Ala Ser Ser
                 305                 310                 315

 Ser Ser Leu Ser Gly Gly His Ala Ser Pro His Leu Phe Thr Phe
                 320                 325                 330

 Pro Pro Thr Pro Pro Lys Asp Val Ser Pro Asp Pro Ser Leu Ser
                 335                 340                 345

 Thr Pro Gly Ser Ala Gly Ser Ala Arg Gln Asp Glu Lys Glu Cys
                 350                 355                 360

 Leu Lys Tyr Gln Val Pro Leu Pro Asp Ser Met Lys Leu Glu Ser
                 365                 370                 375

 Ser His Ser Arg Gly Ser Met Thr Ala Leu Gly Gly Ala Ser Ser
                 380                 385                 390

 Ser Thr His His Pro Ile Thr Thr Tyr Pro Pro Tyr Val Pro Glu
                 395                 400                 405

 Tyr Ser Ser Gly Leu Phe Pro Pro Ser Ser Leu Leu Gly Gly Ser
                 410                 415                 420

 Pro Thr Gly Phe Gly Cys Lys Ser Arg Pro Lys Ala Arg Ser Ser
                 425                 430                 435

 Thr Glu Gly Arg Glu Cys Val Asn Cys Gly Ala Thr Ser Thr Pro
                 440                 445                 450

 Leu Trp Arg Arg Asp Gly Thr Gly His Tyr Leu Cys Asn Ala Cys
                 455                 460                 465

 Gly Leu Tyr His Lys Met Asn Gly Gln Asn Arg Pro Leu Ile Lys
                 470                 475                 480

 Pro Lys Arg Arg Leu Ser Ala Ala Arg Arg Ala Gly Thr Ser Cys
                 485                 490                 495

 Ala Asn Cys Gln Thr Thr Thr Thr Thr Leu Trp Arg Arg Asn Ala
                 500                 505                 510

 Asn Gly Asp Pro Val Cys Asn Ala Cys Gly Leu Tyr Tyr Lys Leu
                 515                 520                 525

 His Asn Ile Asn Arg Pro Leu Thr Met Lys Lys Glu Gly Ile Gln
                 530                 535                 540

 Thr Arg Asn Arg Lys Met Ser Ser Lys Ser Lys Lys Cys Lys Lys
                 545                 550                 555

 Val His Asp Ser Leu Glu Asp Phe Pro Lys Asn Ser Ser Phe Asn
                 560                 565                 570

 Pro Ala Ala Leu Ser Arg His Met Ser Ser Leu Ser His Ile Ser
                 575                 580                 585

 Pro Phe Ser His Ser Ser His Met Leu Thr Thr Pro Thr Pro Met
                 590                 595                 600

 His Pro Pro Ser Ser Leu Ser Phe Gly Pro His His Pro Ser Ser
                 605                 610                 615

 Met Val Thr Ala Met Gly
                 620

<210> 2062
<211> 2365
<212> DNA
<213> Homo sapien

<400> 2062
 tcccagcctt cccatccccc caccgaaagc aaatcattca acgacccccg 50

 accctccgac ggcaggagcc ccccgacctc ccaggcggac cgcccttccc 100

 tccccgcgcg ggttccgggc ccggcgagag ggcgcgacga cagccgaggc 150

 catggaggtg acggcggacc agccgcgctg ggtgagccac caccaccccg 200

 ccgtgctcaa cgggcagcac ccggacacgc accacccggg cctcagccac 250

 tcctacatgg acgcggcgca gtacccgctg ccggaggagg tggatgtgct 300

 ttttaacatc gacggtcaag gcaaccacgt cccgccctac tacggaaact 350

 cggtcagggc cacggtgcag aggtaccctc cgacccacca cgggagccag 400

 gtgtgccgcc cgcctctgct tcatggatcc ctaccctggc tggacggcgg 450

 caaagccctg ggcagccacc acaccgcctc cccctggaat ctcagcccct 500

 tctccaagac gtccatccac cacggctccc cggggcccct ctccgtctac 550

 cccccggcct cgtcctcctc cttgtcgggg ggccacgcca gcccgcacct 600

 cttcaccttc ccgcccaccc cgccgaagga cgtctccccg gacccatcgc 650

 tgtccacccc aggctcggcc ggctcggccc ggcaggacga gaaagagtgc 700

 ctcaagtacc aggtgcccct gcccgacagc atgaagctgg agtcgtccca 750

 ctcccgtggc agcatgaccg ccctgggtgg agcctcctcg tcgacccacc 800

 accccatcac cacctacccg ccctacgtgc ccgagtacag ctccggactc 850

 ttccccccca gcagcctgct gggcggctcc cccaccggct tcggatgcaa 900

 gtccaggccc aaggcccggt ccagcacagg cagggagtgt gtgaactgtg 950

 gggcaacctc gaccccactg tggcggcgag atggcacggg acactacctg 1000

 tgcaacgcct gcgggctcta tcacaaaatg aacggacaga accggcccct 1050

 cattaagccc aagcgaaggc tgtctgcagc caggagagca gggacgtcct 1100

 gtgcgaactg tcagaccacc acaaccacac tctggaggag gaatgccaat 1150

 ggggaccctg tctgcaatgc ctgtgggctc tactacaagc ttcacaatat 1200

 taacagaccc ctgactatga agaaggaagg catccagacc agaaaccgaa 1250

 aaatgtctag caaatccaaa aagtgcaaaa aagtgcatga ctcactggag 1300

 gacttcccca agaacagctc gtttaacccg gccgccctct ccagacacat 1350

 gtcctccctg agccacatct cgcccttcag ccactccagc cacatgctga 1400

 ccacgcccac gccgatgcac ccgccatcca gcctgtcctt tggaccacac 1450

 cacccctcca gcatggtcac cgccatgggt tagagccctg ctcgatgctc 1500

 acagggcccc cagcgagagt ccctgcagtc cctttcgact tgcatttttg 1550

 caggagcagt atcatgaagc ctaaacgcga tggatatatg tttttgaagg 1600

 cagaaagcaa aattatgttt gccactttgc aaaggagctc actgtggtgt 1650

 ctgtgttcca accactgaat ctggacccca tctgtgaata agccattctg 1700

 actcatatcc cctatttaac agggtctcta gtgctgtgaa aaaaaaaaat 1750

 cctgaacatt gcatataact tatattgtaa gaaatactgt acaatgactt 1800

 tattgcatct gggtagctgt aaggcatgaa ggatgccaag aagtttaagg 1850

 aatatgggag aaatagtgtg gaaattaaga agaaactagg tctgatattc 1900

 aaatggacaa actgccagtt ttgtttcctt tcactggcca cagttgtttg 1950

 atgcattaaa agaaaataaa aaaaagaaaa aagagaaaag aaaaaaaaag 2000

 aaaaaagttg taggcgaatc atttgttcaa agctgttggc cctctgcaaa 2050

 ggaaatacca gttctgggca atcagtgtta ccgttcacca gttgccattg 2100

 agggtttcag agagcctttt tctaggccta catgctttgt gaacaagtcc 2150

 ctgtaattgt tgtttgtatg tataattcaa agcaccaaaa taagaaaaga 2200

 tgtagattta tttcatcata ttatacagac cgaactgttg tataaattta 2250

 tttactgcta gtcttaagaa ctgctttctt tcgtttgttt gtttcaatat 2300

 tttccttctc tctcaatttt cggttgaata aactagatta cattcagttg 2350

 gcaaaaaaaa aaaaa 2365

<210> 2063
<211> 443
<212> PRT
<213> Homo sapien

<400> 2063
 Met Glu Val Thr Ala Asp Gln Pro Arg Trp Val Ser His His His
   1               5                  10                  15

 Pro Ala Val Leu Asn Gly Gln His Pro Asp Thr His His Pro Gly
                  20                  25                  30

 Leu Ser His Ser Tyr Met Asp Ala Ala Gln Tyr Pro Leu Pro Glu
                  35                  40                  45

 Glu Val Asp Val Leu Phe Asn Ile Asp Gly Gln Gly Asn His Val
                  50                  55                  60

 Pro Pro Tyr Tyr Gly Asn Ser Val Arg Ala Thr Val Gln Arg Tyr
                  65                  70                  75

 Pro Pro Thr His His Gly Ser Gln Val Cys Arg Pro Pro Leu Leu
                  80                  85                  90

 His Gly Ser Leu Pro Trp Leu Asp Gly Gly Lys Ala Leu Gly Ser
                  95                 100                 105

 His His Thr Ala Ser Pro Trp Asn Leu Ser Pro Phe Ser Lys Thr
                 110                 115                 120

 Ser Ile His His Gly Ser Pro Gly Pro Leu Ser Val Tyr Pro Pro
                 125                 130                 135

 Ala Ser Ser Ser Ser Leu Ser Gly Gly His Ala Ser Pro His Leu
                 140                 145                 150

 Phe Thr Phe Pro Pro Thr Pro Pro Lys Asp Val Ser Pro Asp Pro
                 155                 160                 165

 Ser Leu Ser Thr Pro Gly Ser Ala Gly Ser Ala Arg Gln Asp Glu
                 170                 175                 180

 Lys Glu Cys Leu Lys Tyr Gln Val Pro Leu Pro Asp Ser Met Lys
                 185                 190                 195

 Leu Glu Ser Ser His Ser Arg Gly Ser Met Thr Ala Leu Gly Gly
                 200                 205                 210

 Ala Ser Ser Ser Thr His His Pro Ile Thr Thr Tyr Pro Pro Tyr
                 215                 220                 225

 Val Pro Glu Tyr Ser Ser Gly Leu Phe Pro Pro Ser Ser Leu Leu
                 230                 235                 240

 Gly Gly Ser Pro Thr Gly Phe Gly Cys Lys Ser Arg Pro Lys Ala
                 245                 250                 255

 Arg Ser Ser Thr Gly Arg Glu Cys Val Asn Cys Gly Ala Thr Ser
                 260                 265                 270

 Thr Pro Leu Trp Arg Arg Asp Gly Thr Gly His Tyr Leu Cys Asn
                 275                 280                 285

 Ala Cys Gly Leu Tyr His Lys Met Asn Gly Gln Asn Arg Pro Leu
                 290                 295                 300

 Ile Lys Pro Lys Arg Arg Leu Ser Ala Ala Arg Arg Ala Gly Thr
                 305                 310                 315

 Ser Cys Ala Asn Cys Gln Thr Thr Thr Thr Thr Leu Trp Arg Arg
                 320                 325                 330

 Asn Ala Asn Gly Asp Pro Val Cys Asn Ala Cys Gly Leu Tyr Tyr
                 335                 340                 345

 Lys Leu His Asn Ile Asn Arg Pro Leu Thr Met Lys Lys Glu Gly
                 350                 355                 360

 Ile Gln Thr Arg Asn Arg Lys Met Ser Ser Lys Ser Lys Lys Cys
                 365                 370                 375

 Lys Lys Val His Asp Ser Leu Glu Asp Phe Pro Lys Asn Ser Ser
                 380                 385                 390

 Phe Asn Pro Ala Ala Leu Ser Arg His Met Ser Ser Leu Ser His
                 395                 400                 405

 Ile Ser Pro Phe Ser His Ser Ser His Met Leu Thr Thr Pro Thr
                 410                 415                 420

 Pro Met His Pro Pro Ser Ser Leu Ser Phe Gly Pro His His Pro
                 425                 430                 435

 Ser Ser Met Val Thr Ala Met Gly
                 440

<210> 2064
<211> 3446
<212> DNA
<213> Homo sapien

<400> 2064
 ttctagtttg cggttcaggt ttgccgctgc cggccagcgt cctctggcca 50

 tggacacccc ggaaaatgtc cttcagatgc ttgaagccca catgcagagc 100

 tacaagggca atgaccctct tggtgaatgg gaaagataca tacagtgggt 150

 agaagagaat tttcctgaga ataaagaata cttgataact ttactagaac 200

 atttaatgaa ggaattttta gataagaaga aataccacaa tgacccaaga 250

 ttcatcagtt attgtttaaa atttgctgag tacaacagtg acctccatca 300

 attttttgag tttctgtaca accatgggat tggaaccctg tcatcccctc 350

 tgtacattgc ctgggcgggg catctggaag cccaaggaga gctgcagcat 400

 gccagtgctg tccttcagag aggaattcaa aaccaggctg aacccagaga 450

 gttcctgcaa caacaataca ggttatttca gacacgcctc actgaaaccc 500

 atttgccagc tcaagctaga acctcagaac ctctgcataa tgttcaggtt 550

 ttaaatcaaa tgataacatc aaaatcaaat ccaggaaata acatggcctg 600

 catttctaag aatcagggtt cagagctttc tggagtgata tcttcagctt 650

 gtgataaaga gtcaaatatg gaacgaagag tgatcacgat ttctaaatca 700

 gaatattctg tgcactcatc tttggcatcc aaagttgatg ttgagcaggt 750

 tgttatgtat tgcaaggaga agcttattcg tggggaatca gaattttcct 800

 ttgaagaatt gagagcccag aaatacaatc aacggagaaa gcatgagcaa 850

 tgggtaaatg aagacagaca ttatatgaaa aggaaagaag caaatgcttt 900

 tgaagaacag ctattaaaac agaaaatgga tgaacttcat aagaagttgc 950

 atcaggtggt ggagacatcc catgaggatc tgcccgcttc ccaggaaagg 1000

 tccgaggtta atccagcacg tatggggcca agtgtaggct cccagcagga 1050

 actgagagcg ccatgtcttc cagtaaccta tcagcagaca ccagtgaaca 1100

 tggaaaagaa cccaagagag gcacctcctg ttgttcctcc tttggcaaat 1150

 gctatttctg cagctttggt gtccccagcc accagccaga gcattgctcc 1200

 tcctgttcct ttgaaagccc agacagtaac agactccatg tttgcagtgg 1250

 ccagcaaaga tgctggatgt gtgaataaga gtactcatga attcaagcca 1300

 cagagtggag cagagatcaa agaagggtgt gaaacacata aggttgccaa 1350

 cacaagttct tttcacacaa ctccaaacac atcactggga atggttcagg 1400

 caacgccatc caaagtgcag ccatcaccca ccgtgcacac aaaagaagca 1450

 ttaggtttca tcatgaatat gtttcaggct cctacacttc ctgatatttc 1500

 tgatgacaaa gatgaatggc aatctctaga tcaaaatgaa gatgcatttg 1550

 aagcccagtt tcaaaaaaat gtaaggtcat ctggggcttg gggagtcaat 1600

 aagatcatct cttctttgtc atctgctttt catgtgtttg aagatggaaa 1650

 caaagaaaat tatggattac cacagcctaa aaataaaccc acaggagcca 1700

 ggacctttgg agaacgctct gtcagcagac ttccttcaaa accaaaggag 1750

 gaagtgcctc atgctgaaga gtttttggat gactcaactg tatggggtat 1800

 tcgctgcaac aaaaccctgg cacccagtcc taagagccca ggagacttca 1850

 catctgctgc acaacttgcg tctacaccat tccacaagct tccagtggag 1900

 tcagtgcaca ttttagaaga taaagaaaat gtggtagcaa aacagtgtac 1950

 ccaggcgact ttggattctt gtgaggaaaa catggtggtg ccttcaaggg 2000

 atggaaaatt cagtccaatt caagagaaaa gcccaaaaca ggccttgtcg 2050

 tctcacatgt attcagcatc cttacttcgt ctgagccagc ctgctgcagg 2100

 tggggtactt acctgtgagg cagagttggg cgttgaggct tgcagactca 2150

 cagacactga cgctgccatt gcagaagatc caccagatgc tattgctggg 2200

 ctccaagcag aatggatgca gatgagttca cttgggactg ttgatgctcc 2250

 aaacttcatt gttgggaacc catgggatga taagctgatt ttcaaacttt 2300

 tatctgggct ttctaaacca gtgagttcct atccaaatac ttttgaatgg 2350

 caatgtaaac ttccagccat caagcccaag actgaatttc aattgggttc 2400

 taagctggtc tatgtccatc accttcttgg agaaggagcc tttgcccagg 2450

 tgtacgaagc tacccaggga gatctgaatg atgctaaaaa taaacagaaa 2500

 tttgttttaa aggtccaaaa gcctgccaac ccctgggaat tctacattgg 2550

 gacccagttg atggaaagac taaagccatc tatgcagcac atgtttatga 2600

 agttctattc tgcccactta ttccagaatg gcagtgtatt agtaggagag 2650

 ctctacagct atggaacatt attaaatgcc attaacctct ataaaaatac 2700

 ccctgaaaaa gtgatgcctc aaggtcttgt catctctttt gctatgagaa 2750

 tgctttacat gattgagcaa gtgcatgact gtgaaatcat tcatggagac 2800

 attaaaccag acaatttcat acttggaaac ggatttttgg aacaggatga 2850

 tgaagatgat ttatctgctg gcttggcact gattgacctg ggtcagagta 2900

 tagatatgaa actttttcca aaaggaacta tattcacagc aaagtgtgaa 2950

 acatctggtt ttcagtgtgt tgagatgctc agcaacaaac catggaacta 3000

 ccagatcgat tactttgggg ttgctgcaac agtatattgc atgctctttg 3050

 gcacttacat gaaagtgaaa aatgaaggag gagagtgtaa gcctgaaggt 3100

 ctttttagaa ggcttcctca tttggatatg tggaatgaat tttttcatgt 3150

 tatgttgaat attccagatt gtcatcatct tccatctttg gatttgttaa 3200

 ggcaaaagct gaagaaagta tttcaacaac actatactaa caagattagg 3250

 gccctacgta ataggctaat tgtactgctc ttagaatgta agcgttcacg 3300

 aaaataaaat ttggatatag acagtcctta aaaatcacac tgtaaatatg 3350

 aatctgctca ctttaaacct gttttttttt catttattgt ttatgtaaat 3400

 gtttgttaaa aataaatccc atggaatatt tccatgtaaa aaaaaa 3446

<210> 2065
<211> 1085
<212> PRT
<213> Homo sapien

<400> 2065
 Met Asp Thr Pro Glu Asn Val Leu Gln Met Leu Glu Ala His Met
   1               5                  10                  15

 Gln Ser Tyr Lys Gly Asn Asp Pro Leu Gly Glu Trp Glu Arg Tyr
                  20                  25                  30

 Ile Gln Trp Val Glu Glu Asn Phe Pro Glu Asn Lys Glu Tyr Leu
                  35                  40                  45

 Ile Thr Leu Leu Glu His Leu Met Lys Glu Phe Leu Asp Lys Lys
                  50                  55                  60

 Lys Tyr His Asn Asp Pro Arg Phe Ile Ser Tyr Cys Leu Lys Phe
                  65                  70                  75

 Ala Glu Tyr Asn Ser Asp Leu His Gln Phe Phe Glu Phe Leu Tyr
                  80                  85                  90

 Asn His Gly Ile Gly Thr Leu Ser Ser Pro Leu Tyr Ile Ala Trp
                  95                 100                 105

 Ala Gly His Leu Glu Ala Gln Gly Glu Leu Gln His Ala Ser Ala
                 110                 115                 120

 Val Leu Gln Arg Gly Ile Gln Asn Gln Ala Glu Pro Arg Glu Phe
                 125                 130                 135

 Leu Gln Gln Gln Tyr Arg Leu Phe Gln Thr Arg Leu Thr Glu Thr
                 140                 145                 150

 His Leu Pro Ala Gln Ala Arg Thr Ser Glu Pro Leu His Asn Val
                 155                 160                 165

 Gln Val Leu Asn Gln Met Ile Thr Ser Lys Ser Asn Pro Gly Asn
                 170                 175                 180

 Asn Met Ala Cys Ile Ser Lys Asn Gln Gly Ser Glu Leu Ser Gly
                 185                 190                 195

 Val Ile Ser Ser Ala Cys Asp Lys Glu Ser Asn Met Glu Arg Arg
                 200                 205                 210

 Val Ile Thr Ile Ser Lys Ser Glu Tyr Ser Val His Ser Ser Leu
                 215                 220                 225

 Ala Ser Lys Val Asp Val Glu Gln Val Val Met Tyr Cys Lys Glu
                 230                 235                 240

 Lys Leu Ile Arg Gly Glu Ser Glu Phe Ser Phe Glu Glu Leu Arg
                 245                 250                 255

 Ala Gln Lys Tyr Asn Gln Arg Arg Lys His Glu Gln Trp Val Asn
                 260                 265                 270

 Glu Asp Arg His Tyr Met Lys Arg Lys Glu Ala Asn Ala Phe Glu
                 275                 280                 285

 Glu Gln Leu Leu Lys Gln Lys Met Asp Glu Leu His Lys Lys Leu
                 290                 295                 300

 His Gln Val Val Glu Thr Ser His Glu Asp Leu Pro Ala Ser Gln
                 305                 310                 315

 Glu Arg Ser Glu Val Asn Pro Ala Arg Met Gly Pro Ser Val Gly
                 320                 325                 330

 Ser Gln Gln Glu Leu Arg Ala Pro Cys Leu Pro Val Thr Tyr Gln
                 335                 340                 345

 Gln Thr Pro Val Asn Met Glu Lys Asn Pro Arg Glu Ala Pro Pro
                 350                 355                 360

 Val Val Pro Pro Leu Ala Asn Ala Ile Ser Ala Ala Leu Val Ser
                 365                 370                 375

 Pro Ala Thr Ser Gln Ser Ile Ala Pro Pro Val Pro Leu Lys Ala
                 380                 385                 390

 Gln Thr Val Thr Asp Ser Met Phe Ala Val Ala Ser Lys Asp Ala
                 395                 400                 405

 Gly Cys Val Asn Lys Ser Thr His Glu Phe Lys Pro Gln Ser Gly
                 410                 415                 420

 Ala Glu Ile Lys Glu Gly Cys Glu Thr His Lys Val Ala Asn Thr
                 425                 430                 435

 Ser Ser Phe His Thr Thr Pro Asn Thr Ser Leu Gly Met Val Gln
                 440                 445                 450

 Ala Thr Pro Ser Lys Val Gln Pro Ser Pro Thr Val His Thr Lys
                 455                 460                 465

 Glu Ala Leu Gly Phe Ile Met Asn Met Phe Gln Ala Pro Thr Leu
                 470                 475                 480

 Pro Asp Ile Ser Asp Asp Lys Asp Glu Trp Gln Ser Leu Asp Gln
                 485                 490                 495

 Asn Glu Asp Ala Phe Glu Ala Gln Phe Gln Lys Asn Val Arg Ser
                 500                 505                 510

 Ser Gly Ala Trp Gly Val Asn Lys Ile Ile Ser Ser Leu Ser Ser
                 515                 520                 525

 Ala Phe His Val Phe Glu Asp Gly Asn Lys Glu Asn Tyr Gly Leu
                 530                 535                 540

 Pro Gln Pro Lys Asn Lys Pro Thr Gly Ala Arg Thr Phe Gly Glu
                 545                 550                 555

 Arg Ser Val Ser Arg Leu Pro Ser Lys Pro Lys Glu Glu Val Pro
                 560                 565                 570

 His Ala Glu Glu Phe Leu Asp Asp Ser Thr Val Trp Gly Ile Arg
                 575                 580                 585

 Cys Asn Lys Thr Leu Ala Pro Ser Pro Lys Ser Pro Gly Asp Phe
                 590                 595                 600

 Thr Ser Ala Ala Gln Leu Ala Ser Thr Pro Phe His Lys Leu Pro
                 605                 610                 615

 Val Glu Ser Val His Ile Leu Glu Asp Lys Glu Asn Val Val Ala
                 620                 625                 630

 Lys Gln Cys Thr Gln Ala Thr Leu Asp Ser Cys Glu Glu Asn Met
                 635                 640                 645

 Val Val Pro Ser Arg Asp Gly Lys Phe Ser Pro Ile Gln Glu Lys
                 650                 655                 660

 Ser Pro Lys Gln Ala Leu Ser Ser His Met Tyr Ser Ala Ser Leu
                 665                 670                 675

 Leu Arg Leu Ser Gln Pro Ala Ala Gly Gly Val Leu Thr Cys Glu
                 680                 685                 690

 Ala Glu Leu Gly Val Glu Ala Cys Arg Leu Thr Asp Thr Asp Ala
                 695                 700                 705

 Ala Ile Ala Glu Asp Pro Pro Asp Ala Ile Ala Gly Leu Gln Ala
                 710                 715                 720

 Glu Trp Met Gln Met Ser Ser Leu Gly Thr Val Asp Ala Pro Asn
                 725                 730                 735

 Phe Ile Val Gly Asn Pro Trp Asp Asp Lys Leu Ile Phe Lys Leu
                 740                 745                 750

 Leu Ser Gly Leu Ser Lys Pro Val Ser Ser Tyr Pro Asn Thr Phe
                 755                 760                 765

 Glu Trp Gln Cys Lys Leu Pro Ala Ile Lys Pro Lys Thr Glu Phe
                 770                 775                 780

 Gln Leu Gly Ser Lys Leu Val Tyr Val His His Leu Leu Gly Glu
                 785                 790                 795

 Gly Ala Phe Ala Gln Val Tyr Glu Ala Thr Gln Gly Asp Leu Asn
                 800                 805                 810

 Asp Ala Lys Asn Lys Gln Lys Phe Val Leu Lys Val Gln Lys Pro
                 815                 820                 825

 Ala Asn Pro Trp Glu Phe Tyr Ile Gly Thr Gln Leu Met Glu Arg
                 830                 835                 840

 Leu Lys Pro Ser Met Gln His Met Phe Met Lys Phe Tyr Ser Ala
                 845                 850                 855

 His Leu Phe Gln Asn Gly Ser Val Leu Val Gly Glu Leu Tyr Ser
                 860                 865                 870

 Tyr Gly Thr Leu Leu Asn Ala Ile Asn Leu Tyr Lys Asn Thr Pro
                 875                 880                 885

 Glu Lys Val Met Pro Gln Gly Leu Val Ile Ser Phe Ala Met Arg
                 890                 895                 900

 Met Leu Tyr Met Ile Glu Gln Val His Asp Cys Glu Ile Ile His
                 905                 910                 915

 Gly Asp Ile Lys Pro Asp Asn Phe Ile Leu Gly Asn Gly Phe Leu
                 920                 925                 930

 Glu Gln Asp Asp Glu Asp Asp Leu Ser Ala Gly Leu Ala Leu Ile
                 935                 940                 945

 Asp Leu Gly Gln Ser Ile Asp Met Lys Leu Phe Pro Lys Gly Thr
                 950                 955                 960

 Ile Phe Thr Ala Lys Cys Glu Thr Ser Gly Phe Gln Cys Val Glu
                 965                 970                 975

 Met Leu Ser Asn Lys Pro Trp Asn Tyr Gln Ile Asp Tyr Phe Gly
                 980                 985                 990

 Val Ala Ala Thr Val Tyr Cys Met Leu Phe Gly Thr Tyr Met Lys
                 995                1000                1005

 Val Lys Asn Glu Gly Gly Glu Cys Lys Pro Glu Gly Leu Phe Arg
                1010                1015                1020

 Arg Leu Pro His Leu Asp Met Trp Asn Glu Phe Phe His Val Met
                1025                1030                1035

 Leu Asn Ile Pro Asp Cys His His Leu Pro Ser Leu Asp Leu Leu
                1040                1045                1050

 Arg Gln Lys Leu Lys Lys Val Phe Gln Gln His Tyr Thr Asn Lys
                1055                1060                1065

 Ile Arg Ala Leu Arg Asn Arg Leu Ile Val Leu Leu Leu Glu Cys
                1070                1075                1080

 Lys Arg Ser Arg Lys
                1085

<210> 2066
<211> 2201
<212> DNA
<213> Homo sapien

<400> 2066
 gggggtggga agagctgaag caggcgctct tggctcggcg cggcccgctg 50

 caatccgtgg aggaacgcgc cgccgagcca ccatcatgcc tgggcactta 100

 caggaaggct tcggctgcgt ggtcaccaac cgattcgacc agttatttga 150

 cgacgaatcg gaccccttcg aggtgctgaa ggcagcagag aacaagaaaa 200

 aagaagccgg cgggggcggc gttgggggcc ctggggccaa gagcgcagct 250

 caggccgcgg cccagaccaa ctccaacgcg gcaggcaaac agctgcgcaa 300

 ggagtcccag aaagaccgca agaacccgct gccccccagc gttggcgtgg 350

 ttgacaagaa agaggagacg cagccgcccg tggcgcttaa gaaagaagga 400

 ataagacgag ttggaagaag acctgatcaa caacttcagg gtgaagggaa 450

 aataattgat agaagaccag aaaggcgacc acctcgtgaa cgaagattcg 500

 aaaagccact tgaagaaaag ggtgaaggag gcgaattttc agttgataga 550

 ccgattattg accgacctat tcgaggtcgt ggtggtcttg gaagaggtcg 600

 agggggccgt ggacgtggaa tgggccgagg agatggattt gattctcgtg 650

 gcaaacgtga atttgatagg catagtggaa gtgatagatc tggcctgaag 700

 cacgaggaca aacgtggagg tagcggatct cacaactggg gaactgtcaa 750

 agacgaatta actgacttgg atcaatcaaa tgtgactgag gaaacacctg 800

 aaggtgaaga acatcatcca gtggcagaca ctgaaaataa ggagaatgaa 850

 gttgaagagg taaaagagga gggtccaaaa gagatgactt tggatgagtg 900

 gaaggctatt caaaataagg accgggcaaa agtagaattt aatatccgaa 950

 aaccaaatga aggtgctgat gggcagtgga agaagggatt tgttcttcat 1000

 aaatcaaaga gtgaagaggc tcatgctgaa gattcggtta tggaccatca 1050

 tttccggaag ccagcaaatg atataacgtc tcagctggag atcaattttg 1100

 gagaccttgg ccgcccagga cgtggcggca ggggaggacg aggtggacgt 1150

 gggcgtggtg ggcgcccaaa ccgtggcagc aggaccgaca agtcaagtgc 1200

 ttctgctcct gatgtggatg acccagaggc attcccagct ctggcttaac 1250

 tggatgccat aagacaaccc tggttccttt gtgaaccctt ctgttcaaag 1300

 cttttgcatg cttaaggatt ccaaacgact aagaaattaa aaaaaaaaag 1350

 actgtcattc ataccattca cacctaaaga ctgaatttta tctgttttaa 1400

 aaatgaactt ctcccgctac acagaagtaa caaatatggt agtcagtttt 1450

 gtatttagaa atgtattggt agcagggatg ttttcataat tttcagagat 1500

 tatgcattct tcatgaatac ttttgtattg ctgcttgcaa atatgcattt 1550

 ccaaacttga aatataggtg tgaacagtgt gtaccagttt aaagctttca 1600

 cttcatttgt gttttttaat taaggactta gaagttcccc caattacaaa 1650

 ctggttttaa atattggaca tactggtttt aatacctgct ttgcatattc 1700

 acacatggtc aactgggaca tgttaaactt tgatttgtca aattttatgc 1750

 tgtgtggaat actaactata tgtattttaa cttagtttta atattttcat 1800

 tttgggggaa aaatcttttt tcacttctca tgatagctgt tatatatata 1850

 tgctaaatct ttatatacag aaatatcagt acttgaacaa attcaaagca 1900

 catttggttt attaaccctt gctccttgca tggctcatta ggttcaaatt 1950

 ataactaatt tacattttca gctatattta ctttttaaat gcttgagttt 2000

 cccattttaa aatctaaact agacatctta attggtgaaa gttgtttaaa 2050

 ctacttattg ttggtaggca catcgtgtca agtgaagtag ttttataggt 2100

 atgggttttt tctccccctt caccagggtg ggtggaataa gttgatttgg 2150

 ccaatgtgta atatttaaac tgttctgtaa aataaaaaaa aaaaaaaaaa 2200

 a 2201

<210> 2067
<211> 387
<212> PRT
<213> Homo sapien

<400> 2067
 Met Pro Gly His Leu Gln Glu Gly Phe Gly Cys Val Val Thr Asn
   1               5                  10                  15

 Arg Phe Asp Gln Leu Phe Asp Asp Glu Ser Asp Pro Phe Glu Val
                  20                  25                  30

 Leu Lys Ala Ala Glu Asn Lys Lys Lys Glu Ala Gly Gly Gly Gly
                  35                  40                  45

 Val Gly Gly Pro Gly Ala Lys Ser Ala Ala Gln Ala Ala Ala Gln
                  50                  55                  60

 Thr Asn Ser Asn Ala Ala Gly Lys Gln Leu Arg Lys Glu Ser Gln
                  65                  70                  75

 Lys Asp Arg Lys Asn Pro Leu Pro Pro Ser Val Gly Val Val Asp
                  80                  85                  90

 Lys Lys Glu Glu Thr Gln Pro Pro Val Ala Leu Lys Lys Glu Gly
                  95                 100                 105

 Ile Arg Arg Val Gly Arg Arg Pro Asp Gln Gln Leu Gln Gly Glu
                 110                 115                 120

 Gly Lys Ile Ile Asp Arg Arg Pro Glu Arg Arg Pro Pro Arg Glu
                 125                 130                 135

 Arg Arg Phe Glu Lys Pro Leu Glu Glu Lys Gly Glu Gly Gly Glu
                 140                 145                 150

 Phe Ser Val Asp Arg Pro Ile Ile Asp Arg Pro Ile Arg Gly Arg
                 155                 160                 165

 Gly Gly Leu Gly Arg Gly Arg Gly Gly Arg Gly Arg Gly Met Gly
                 170                 175                 180

 Arg Gly Asp Gly Phe Asp Ser Arg Gly Lys Arg Glu Phe Asp Arg
                 185                 190                 195

 His Ser Gly Ser Asp Arg Ser Gly Leu Lys His Glu Asp Lys Arg
                 200                 205                 210

 Gly Gly Ser Gly Ser His Asn Trp Gly Thr Val Lys Asp Glu Leu
                 215                 220                 225

 Thr Asp Leu Asp Gln Ser Asn Val Thr Glu Glu Thr Pro Glu Gly
                 230                 235                 240

 Glu Glu His His Pro Val Ala Asp Thr Glu Asn Lys Glu Asn Glu
                 245                 250                 255

 Val Glu Glu Val Lys Glu Glu Gly Pro Lys Glu Met Thr Leu Asp
                 260                 265                 270

 Glu Trp Lys Ala Ile Gln Asn Lys Asp Arg Ala Lys Val Glu Phe
                 275                 280                 285

 Asn Ile Arg Lys Pro Asn Glu Gly Ala Asp Gly Gln Trp Lys Lys
                 290                 295                 300

 Gly Phe Val Leu His Lys Ser Lys Ser Glu Glu Ala His Ala Glu
                 305                 310                 315

 Asp Ser Val Met Asp His His Phe Arg Lys Pro Ala Asn Asp Ile
                 320                 325                 330

 Thr Ser Gln Leu Glu Ile Asn Phe Gly Asp Leu Gly Arg Pro Gly
                 335                 340                 345

 Arg Gly Gly Arg Gly Gly Arg Gly Gly Arg Gly Arg Gly Gly Arg
                 350                 355                 360

 Pro Asn Arg Gly Ser Arg Thr Asp Lys Ser Ser Ala Ser Ala Pro
                 365                 370                 375

 Asp Val Asp Asp Pro Glu Ala Phe Pro Ala Leu Ala
                 380                 385

<210> 2068
<211> 3668
<212> DNA
<213> Homo sapien

<400> 2068
 ggcagagggt gggccttagg acgggtctcc cttaaactgg gcgatcaggc 50

 agcgacccta gaggcgtctg tagggtaaag ctgggggttc tgtagccgga 100

 ggcggcggcg agtccagaac gtcctggcct tacagggaga aggcgtcact 150

 cgcggttaca agtgcctgac cctcactcca gttggcggag gaggagaagg 200

 aaggggccgg gccgggtccc ctcccctcgc gccccggatg gatgtgcccg 250

 gcccggtgtc tcggcgggcg gcggcggcgg cggccactgt gctcctgcgg 300

 accgctcggg tccgtcgcga atgctggttc ttgccgaccg cgctgctctg 350

 cgcctacggc ttcttcgcca gcctcaggcc gtccgagccc ttcctgaccc 400

 cgtacctgct ggggccggac aagaacctga ccgagaggga ggtcttcaat 450

 gaaatttatc cagtatggac ttactcttac ctggtgctac tgtttcctgt 500

 gttccttgcc acagactacc tccgttataa acctgttgtt ctactgcagg 550

 ggctcagcct tattgttaca tggtttatgc tgctctatgc ccagggactg 600

 ctggccattc aatttctaga atttttttat ggcatcgcca cagccactga 650

 aattgcctat tactcttata tctacagtgt ggtggacctg ggcatgtacc 700

 agaaagtcac aagttactgt cgaagtgcca ctttggtggg ctttacagtg 750

 ggctctgtcc tagggcaaat ccttgtctca gtggcaggct ggtcgctgtt 800

 cagcctgaat gtcatctctc ttacctgtgt ttcagtggct tttgctgtgg 850

 cctggttttt acctatgcca cagaagagcc tcttctttca ccacattcct 900

 tctacctgcc agagagtgaa tggcatcaag gtacaaaatg gtggcattgt 950

 tactgacacc ccagcttcta accaccttcc tggctgggag gacattgagt 1000

 caaaaatccc tctaaatatg gaggagcctc ccgtggagga accggaaccc 1050

 aagccagacc gtctccttgt attgaaagta ctatggaatg atttcctgat 1100

 gtgctactcc tctcgccctc ttctctgctg gtctgtgtgg tgggccctct 1150

 ctacctgtgg ctattttcaa gttgtgaact acacacaggg cctgtgggag 1200

 aaagtgatgc cttctcgcta tgctgctatc tataatggtg gcgtggaggc 1250

 cgtttcaacc ttactgggtg ctgttgctgt gtttgcagtt ggttatataa 1300

 aaatatcctg gtcaacttgg ggagaaatga cattatctct cttttctctc 1350

 ctgattgctg ctgcagtgta tatcatggac actgtgggta acatttgggt 1400

 gtgctatgca tcctatgttg tcttcagaat catctacatg ttactcatca 1450

 cgatagcaac ttttcaaatt gctgcaaacc tcagcatgga acgctatgcc 1500

 ctagtatttg gtgtaaatac cttcattgcc ctggcactgc agacgctgct 1550

 cactctaatt gtggtagatg ccagtggcct tggattagaa attaccactc 1600

 agtttttgat ctatgccagt tattttgcac tcatcgctgt ggttttcctg 1650

 gccagtggtg cagtcagtgt tatgaagaaa tgtagaaagc tggaagatcc 1700

 acaatcaagt tctcaagtaa ccacttcata atatactgct gaagggcttc 1750

 ttcttatagc aagaactctg cacagcaact gcctggatgt atttgatttt 1800

 ttaaagcgta gacatatatt tatgaatgtg catttcttga cttcacagca 1850

 gccacttgac taataccttg tgttccggga ataacatgat actattcaga 1900

 ggagccagaa gtaaagttta tttcatggat tatttatgag agctaattta 1950

 aggatgactt tttttctgat tcaaaagtga acttgatttt aaaaaccagt 2000

 caagagcaat caaagcagca catggtgttg tatacttcat tagcaagtga 2050

 gtttggtgtt ttataggtca catatgtctg tatctactta gccagatgct 2100

 tggcctggtg ggaccagggc tccacagagg ccacaaaatg ttgcaagtca 2150

 tgatggatgg aaatatgttc taacagcatc tgcctctatt caatttaatt 2200

 cttatttctg tgttactcat gtacattggt ctttctacat agttattcta 2250

 tcactggcaa tatttgttct ggtttagtgt tctgtatttt aaggtgtacg 2300

 tatcatttct aattttaagt tattttaaaa aaattcatca tatgaatgtt 2350

 cttggttccc attgtgacga ttatttattt ctgtaaaatt tgtttagaag 2400

 tacgtttttg cattattcat atgcttccca gagaagctca tttagttaga 2450

 aaataaggca agttttgaag cctgctaaat gaagagactt aagaaagctt 2500

 aaggtacgct tgcttgtctt taaatcttca atatgaagga ctattaattc 2550

 caagattaaa agttcatata taggctaaag atgtaactag gccatttgta 2600

 tttgtattcc cttttatttc caaaataaaa tgaaaaatct ttttttaata 2650

 atttcatccc tatttatagt ttttatatta atttgttttt cttatccaag 2700

 taaagatgtc aataggaatt gcattagtcc aaggcctttt tcataaactg 2750

 agcctctttt caattatttc aatgggacag gaactaggat agatgtgatt 2800

 cctgcatttt tttaccttaa atctgccttt gtttctaaag gtagatcatc 2850

 ttgaatattt gcttaaaatt gctagtgatt tcattaccaa gttacttgaa 2900

 aaaatgttct atatgcattt aattctgaaa tcagtctacc aaggggctgc 2950

 tagtatatgt cagacatgaa aactatttta aagctgactt tgttgcctta 3000

 tcttgaaaag aatctagata ggtgctttta actggggtat taactttttt 3050

 agaatgacac agctgaacag tgttaataat agtgtgtcaa gattgcaaag 3100

 tcgacatact catttggttt aagcaggaat cctagaagca aatggatggg 3150

 gataagaata ggtcattttc tattcaccat cctttactat taagggaaag 3200

 gaaaagaaca ctagctaagg aagggaaagg gaagtgatat cataaaagta 3250

 gcaaccttca ttttacattc tgtctgtttt tctttttttg ctttgttttg 3300

 tttgtgctaa tttgggaatt gtgtactccg aaacaagtag aaaagtgctg 3350

 tttgagggat tttattaaat ctttttttaa tggaatgtgg tacaaattgt 3400

 tcatgttacc aaagcaatat ttccctggaa tttaattcaa agtttgtggc 3450

 atacaacctg agccttttct tatataagac aagaatatgt tcacatcttg 3500

 gtatgtggcc atatttatag aatgctgaac tcaatgtgca agttgtactg 3550

 tatgcagttt tgtaaataag tgaaaataat ttgttgtact ttttattcaa 3600

 ttctgtatag attataaaat tatttttatt aaataaatat tttacagtat 3650

 aaaaaaaaaa aaaaaaaa 3668

<210> 2069
<211> 497
<212> PRT
<213> Homo sapien

<400> 2069
 Met Asp Val Pro Gly Pro Val Ser Arg Arg Ala Ala Ala Ala Ala
   1               5                  10                  15

 Ala Thr Val Leu Leu Arg Thr Ala Arg Val Arg Arg Glu Cys Trp
                  20                  25                  30

 Phe Leu Pro Thr Ala Leu Leu Cys Ala Tyr Gly Phe Phe Ala Ser
                  35                  40                  45

 Leu Arg Pro Ser Glu Pro Phe Leu Thr Pro Tyr Leu Leu Gly Pro
                  50                  55                  60

 Asp Lys Asn Leu Thr Glu Arg Glu Val Phe Asn Glu Ile Tyr Pro
                  65                  70                  75

 Val Trp Thr Tyr Ser Tyr Leu Val Leu Leu Phe Pro Val Phe Leu
                  80                  85                  90

 Ala Thr Asp Tyr Leu Arg Tyr Lys Pro Val Val Leu Leu Gln Gly
                  95                 100                 105

 Leu Ser Leu Ile Val Thr Trp Phe Met Leu Leu Tyr Ala Gln Gly
                 110                 115                 120

 Leu Leu Ala Ile Gln Phe Leu Glu Phe Phe Tyr Gly Ile Ala Thr
                 125                 130                 135

 Ala Thr Glu Ile Ala Tyr Tyr Ser Tyr Ile Tyr Ser Val Val Asp
                 140                 145                 150

 Leu Gly Met Tyr Gln Lys Val Thr Ser Tyr Cys Arg Ser Ala Thr
                 155                 160                 165

 Leu Val Gly Phe Thr Val Gly Ser Val Leu Gly Gln Ile Leu Val
                 170                 175                 180

 Ser Val Ala Gly Trp Ser Leu Phe Ser Leu Asn Val Ile Ser Leu
                 185                 190                 195

 Thr Cys Val Ser Val Ala Phe Ala Val Ala Trp Phe Leu Pro Met
                 200                 205                 210

 Pro Gln Lys Ser Leu Phe Phe His His Ile Pro Ser Thr Cys Gln
                 215                 220                 225

 Arg Val Asn Gly Ile Lys Val Gln Asn Gly Gly Ile Val Thr Asp
                 230                 235                 240

 Thr Pro Ala Ser Asn His Leu Pro Gly Trp Glu Asp Ile Glu Ser
                 245                 250                 255

 Lys Ile Pro Leu Asn Met Glu Glu Pro Pro Val Glu Glu Pro Glu
                 260                 265                 270

 Pro Lys Pro Asp Arg Leu Leu Val Leu Lys Val Leu Trp Asn Asp
                 275                 280                 285

 Phe Leu Met Cys Tyr Ser Ser Arg Pro Leu Leu Cys Trp Ser Val
                 290                 295                 300

 Trp Trp Ala Leu Ser Thr Cys Gly Tyr Phe Gln Val Val Asn Tyr
                 305                 310                 315

 Thr Gln Gly Leu Trp Glu Lys Val Met Pro Ser Arg Tyr Ala Ala
                 320                 325                 330

 Ile Tyr Asn Gly Gly Val Glu Ala Val Ser Thr Leu Leu Gly Ala
                 335                 340                 345

 Val Ala Val Phe Ala Val Gly Tyr Ile Lys Ile Ser Trp Ser Thr
                 350                 355                 360

 Trp Gly Glu Met Thr Leu Ser Leu Phe Ser Leu Leu Ile Ala Ala
                 365                 370                 375

 Ala Val Tyr Ile Met Asp Thr Val Gly Asn Ile Trp Val Cys Tyr
                 380                 385                 390

 Ala Ser Tyr Val Val Phe Arg Ile Ile Tyr Met Leu Leu Ile Thr
                 395                 400                 405

 Ile Ala Thr Phe Gln Ile Ala Ala Asn Leu Ser Met Glu Arg Tyr
                 410                 415                 420

 Ala Leu Val Phe Gly Val Asn Thr Phe Ile Ala Leu Ala Leu Gln
                 425                 430                 435

 Thr Leu Leu Thr Leu Ile Val Val Asp Ala Ser Gly Leu Gly Leu
                 440                 445                 450

 Glu Ile Thr Thr Gln Phe Leu Ile Tyr Ala Ser Tyr Phe Ala Leu
                 455                 460                 465

 Ile Ala Val Val Phe Leu Ala Ser Gly Ala Val Ser Val Met Lys
                 470                 475                 480

 Lys Cys Arg Lys Leu Glu Asp Pro Gln Ser Ser Ser Gln Val Thr
                 485                 490                 495

 Thr Ser


<210> 2070
<211> 3928
<212> DNA
<213> Homo sapien

<400> 2070
 agcggagtgc tgctgcggcg tcccgcggcc tccccgagtc gggcgggagg 50

 ggagagcggg tgtggatttg tcttgacggt aattgttgcg tttccacgtc 100

 tcggaggcct gcgcgctggg ttgctccttc ttcgggagcg agctgttctc 150

 agcgatccca ctcccagccg gggctcccca cacacactgg gctgcgtgcg 200

 tgtggagtgg gacccgcgca cacgcgtgtc tctggacagc tacggcgccg 250

 aaagaactaa aattccagat ggcaaactca atgaatggca gaaaccctgg 300

 tggtcgagga ggaaatcccc gaaaaggtcg aattttgggt attattgatg 350

 ctattcagga tgcagttgga ccccctaagc aagctgccgc agatcgcagg 400

 accgtggaga agacttggaa gctcatggac aaagtggtaa gactgtgcca 450

 aaatcccaaa cttcagttga aaaatagccc accatatata cttgatattt 500

 tgcctgatac atatcagcat ttacgactta tattgagtaa atatgatgac 550

 aaccagaaac ttgcccaact cagtgagaat gagtacttta aaatctacat 600

 tgatagcctt atgaaaaagt caaaacgggc aataagactc tttaaagaag 650

 gcaaggagag aatgtatgaa gaacagtcac aggacagacg aaatctcaca 700

 aaactgtccc ttatcttcag tcacatgctg gcagaaatca aagcaatctt 750

 tcccaatggt caattccagg gagataactt tcgtatcaca aaagcagatg 800

 ctgctgaatt ctggagaaag ttttttggag acaaaactat cgtaccatgg 850

 aaagtattca gacagtgcct tcatgaggtc caccagatta gctctggcct 900

 ggaagcaatg gctctaaaat caacaattga tttaacttgc aatgattaca 950

 tttcagtttt tgaatttgat atttttacca ggctgtttca gccttggggc 1000

 tctattttgc ggaattggaa tttcttagct gtgacacatc caggttacat 1050

 ggcatttctc acatatgatg aagttaaagc acgactacag aaatatagca 1100

 ccaaacccgg aagctatatt ttccggttaa gttgcactcg attgggacag 1150

 tgggccattg gctatgtgac tggggatggg aatatcttac agaccatacc 1200

 tcataacaag cccttatttc aagccctgat tgatggcagc agggaaggat 1250

 tttatcttta tcctgatggg aggagttata atcctgattt aactggatta 1300

 tgtgaaccta cacctcatga ccatataaaa gttacacagg aacaatatga 1350

 attatattgt gaaatgggct ccacttttca gctctgtaag atttgtgcag 1400

 agaatgacaa agatgtcaag attgagcctt gtgggcattt gatgtgcacc 1450

 tcttgcctta cggcatggca ggagtcggat ggtcagggct gccctttctg 1500

 tcgttgtgaa ataaaaggaa ctgagcccat aatcgtggat ccctttgatc 1550

 caagagatga aggctccagg tgttgcagca tcattgaccc ctttggcatg 1600

 ccgatgctcg acttggacga cgatgatgat cgtgaggagt ccttgatgat 1650

 gaatcggttg gcaaacgtcc gaaagtgcac tgacaggcag aactcaccag 1700

 tcacatcacc aggatcctct ccccttgccc agagaagaaa gccacagcct 1750

 gacccactcc agatcccaca tctaagcctg ccacccgtgc ctcctcgcct 1800

 ggatctaatt cagaaaggca tagttagatc tccctgtggc agcccaacgg 1850

 gttcaccaaa gtcttctcct tgcatggtga gaaaacaaga taaaccactc 1900

 ccagcaccac ctcctccctt aagagatcct cctccaccgc cacctgaaag 1950

 acctccacca atcccaccag acaatagact gagtagacac atccatcatg 2000

 tggaaagcgt gccttccaaa gacccgccaa tgcctcttga agcatggtgc 2050

 cctcgggatg tgtttgggac taatcagctt gtgggatgtc gactcctagg 2100

 ggagggctct ccaaaacctg gaatcacagc gagttcaaat gtcaatggaa 2150

 ggcacagtag agtgggctct gacccagtgc ttatgcggaa acacagacgc 2200

 catgatttgc ctttagaagg agctaaggtc ttttccaatg gtcaccttgg 2250

 aagtgaagaa tatgatgttc ctccccggct ttctcctcct cctccagtta 2300

 ccaccctcct ccctagcata aagtgtactg gtccgttagc aaattctctt 2350

 tcagagaaaa caagagaccc agtagaggaa gatgatgatg aatacaagat 2400

 tccttcatcc caccctgttt ccctgaattc acaaccatct cattgtcata 2450

 atgtaaaacc tcctgttcgg tcttgtgata atggtcactg tatgctgaat 2500

 ggaacacatg gtccatcttc agagaagaaa tcaaacatcc ctgacttaag 2550

 catatattta aagggagatg tttttgattc agcctctgat cccgtgccat 2600

 taccacctgc caggcctcca actcgggaca atccaaagca tggttcttca 2650

 ctcaacagga cgccctctga ttatgatctt ctcatccctc cattaggtga 2700

 agatgctttt gatgccctcc ctccatctct cccacctccc ccacctcctg 2750

 caaggcatag tctcattgaa cattcaaaac ctcctggctc cagtagccgg 2800

 ccatcctcag gacaggatct ttttcttctt ccttcagatc cctttgttga 2850

 tctagcaagt ggccaagttc ctttgcctcc cgctagaagg ttaccaggtg 2900

 aaaatgtcaa aactaacaga acatcacagg actatgatca gcttccttca 2950

 tgttcagatg gttcacaggc accagccaga ccccctaaac cacgaccgcg 3000

 caggactgca ccagaaattc accacagaaa accccatggg cctgaggcgg 3050

 cattggaaaa tgtcgatgca aaaattgcaa aactcatggg agagggttat 3100

 gcctttgaag aggtgaagag agccttagag atagcccaga ataatgtcga 3150

 agttgcccgg agcatcctcc gagaatttgc cttccctcct ccagtatccc 3200

 cacgtctaaa tctatagcag ccagaactgt agacaccaaa atggaaagca 3250

 atcgatgtat tccaagagtg tggaaataaa gagaactgag atggaattca 3300

 agagagaagt gtctcctcct cgtgtagcag cttgagaaga ggcttgggag 3350

 tgcagcttct caaaggagac cgatgcttgc tcaggatgtc gacagctgtg 3400

 gcttccttgt ttttgctagc catattttta aatcagggtt gaactgacaa 3450

 aaataattta aagacgttta cttcccttga actttgaacc tgtgaaatgc 3500

 tttaccttgt ttacaatttg gcaaagttgc agtttgttct tgtttttagt 3550

 ttagttttgt tttggtgttt tgatacctgt actgtgttct tcacagaccc 3600

 tttgtagcgt ggtcaggtct gctgtaacat ttcccaccaa ctctcttgct 3650

 gtccacatca acagctaaat catttattca tatggatctc taccatcccc 3700

 atgccttgcc caggtccagt tccatttctc tcattcacaa gatgctttga 3750

 aggttctgat tttcaactga tcaaactaat gcaaaaaaaa aagtatgtat 3800

 tcttcactac tgagtttctt ctttggaaac catcactatt gagagatggg 3850

 aaaaacctga atgtataaag catttatttg tcaataaact gccttttgta 3900

 aggggttttc acaaaaaaaa aaaaaaaa 3928

<210> 2071
<211> 982
<212> PRT
<213> Homo sapien

<400> 2071
 Met Ala Asn Ser Met Asn Gly Arg Asn Pro Gly Gly Arg Gly Gly
   1               5                  10                  15

 Asn Pro Arg Lys Gly Arg Ile Leu Gly Ile Ile Asp Ala Ile Gln
                  20                  25                  30

 Asp Ala Val Gly Pro Pro Lys Gln Ala Ala Ala Asp Arg Arg Thr
                  35                  40                  45

 Val Glu Lys Thr Trp Lys Leu Met Asp Lys Val Val Arg Leu Cys
                  50                  55                  60

 Gln Asn Pro Lys Leu Gln Leu Lys Asn Ser Pro Pro Tyr Ile Leu
                  65                  70                  75

 Asp Ile Leu Pro Asp Thr Tyr Gln His Leu Arg Leu Ile Leu Ser
                  80                  85                  90

 Lys Tyr Asp Asp Asn Gln Lys Leu Ala Gln Leu Ser Glu Asn Glu
                  95                 100                 105

 Tyr Phe Lys Ile Tyr Ile Asp Ser Leu Met Lys Lys Ser Lys Arg
                 110                 115                 120

 Ala Ile Arg Leu Phe Lys Glu Gly Lys Glu Arg Met Tyr Glu Glu
                 125                 130                 135

 Gln Ser Gln Asp Arg Arg Asn Leu Thr Lys Leu Ser Leu Ile Phe
                 140                 145                 150

 Ser His Met Leu Ala Glu Ile Lys Ala Ile Phe Pro Asn Gly Gln
                 155                 160                 165

 Phe Gln Gly Asp Asn Phe Arg Ile Thr Lys Ala Asp Ala Ala Glu
                 170                 175                 180

 Phe Trp Arg Lys Phe Phe Gly Asp Lys Thr Ile Val Pro Trp Lys
                 185                 190                 195

 Val Phe Arg Gln Cys Leu His Glu Val His Gln Ile Ser Ser Gly
                 200                 205                 210

 Leu Glu Ala Met Ala Leu Lys Ser Thr Ile Asp Leu Thr Cys Asn
                 215                 220                 225

 Asp Tyr Ile Ser Val Phe Glu Phe Asp Ile Phe Thr Arg Leu Phe
                 230                 235                 240

 Gln Pro Trp Gly Ser Ile Leu Arg Asn Trp Asn Phe Leu Ala Val
                 245                 250                 255

 Thr His Pro Gly Tyr Met Ala Phe Leu Thr Tyr Asp Glu Val Lys
                 260                 265                 270

 Ala Arg Leu Gln Lys Tyr Ser Thr Lys Pro Gly Ser Tyr Ile Phe
                 275                 280                 285

 Arg Leu Ser Cys Thr Arg Leu Gly Gln Trp Ala Ile Gly Tyr Val
                 290                 295                 300

 Thr Gly Asp Gly Asn Ile Leu Gln Thr Ile Pro His Asn Lys Pro
                 305                 310                 315

 Leu Phe Gln Ala Leu Ile Asp Gly Ser Arg Glu Gly Phe Tyr Leu
                 320                 325                 330

 Tyr Pro Asp Gly Arg Ser Tyr Asn Pro Asp Leu Thr Gly Leu Cys
                 335                 340                 345

 Glu Pro Thr Pro His Asp His Ile Lys Val Thr Gln Glu Gln Tyr
                 350                 355                 360

 Glu Leu Tyr Cys Glu Met Gly Ser Thr Phe Gln Leu Cys Lys Ile
                 365                 370                 375

 Cys Ala Glu Asn Asp Lys Asp Val Lys Ile Glu Pro Cys Gly His
                 380                 385                 390

 Leu Met Cys Thr Ser Cys Leu Thr Ala Trp Gln Glu Ser Asp Gly
                 395                 400                 405

 Gln Gly Cys Pro Phe Cys Arg Cys Glu Ile Lys Gly Thr Glu Pro
                 410                 415                 420

 Ile Ile Val Asp Pro Phe Asp Pro Arg Asp Glu Gly Ser Arg Cys
                 425                 430                 435

 Cys Ser Ile Ile Asp Pro Phe Gly Met Pro Met Leu Asp Leu Asp
                 440                 445                 450

 Asp Asp Asp Asp Arg Glu Glu Ser Leu Met Met Asn Arg Leu Ala
                 455                 460                 465

 Asn Val Arg Lys Cys Thr Asp Arg Gln Asn Ser Pro Val Thr Ser
                 470                 475                 480

 Pro Gly Ser Ser Pro Leu Ala Gln Arg Arg Lys Pro Gln Pro Asp
                 485                 490                 495

 Pro Leu Gln Ile Pro His Leu Ser Leu Pro Pro Val Pro Pro Arg
                 500                 505                 510

 Leu Asp Leu Ile Gln Lys Gly Ile Val Arg Ser Pro Cys Gly Ser
                 515                 520                 525

 Pro Thr Gly Ser Pro Lys Ser Ser Pro Cys Met Val Arg Lys Gln
                 530                 535                 540

 Asp Lys Pro Leu Pro Ala Pro Pro Pro Pro Leu Arg Asp Pro Pro
                 545                 550                 555

 Pro Pro Pro Pro Glu Arg Pro Pro Pro Ile Pro Pro Asp Asn Arg
                 560                 565                 570

 Leu Ser Arg His Ile His His Val Glu Ser Val Pro Ser Lys Asp
                 575                 580                 585

 Pro Pro Met Pro Leu Glu Ala Trp Cys Pro Arg Asp Val Phe Gly
                 590                 595                 600

 Thr Asn Gln Leu Val Gly Cys Arg Leu Leu Gly Glu Gly Ser Pro
                 605                 610                 615

 Lys Pro Gly Ile Thr Ala Ser Ser Asn Val Asn Gly Arg His Ser
                 620                 625                 630

 Arg Val Gly Ser Asp Pro Val Leu Met Arg Lys His Arg Arg His
                 635                 640                 645

 Asp Leu Pro Leu Glu Gly Ala Lys Val Phe Ser Asn Gly His Leu
                 650                 655                 660

 Gly Ser Glu Glu Tyr Asp Val Pro Pro Arg Leu Ser Pro Pro Pro
                 665                 670                 675

 Pro Val Thr Thr Leu Leu Pro Ser Ile Lys Cys Thr Gly Pro Leu
                 680                 685                 690

 Ala Asn Ser Leu Ser Glu Lys Thr Arg Asp Pro Val Glu Glu Asp
                 695                 700                 705

 Asp Asp Glu Tyr Lys Ile Pro Ser Ser His Pro Val Ser Leu Asn
                 710                 715                 720

 Ser Gln Pro Ser His Cys His Asn Val Lys Pro Pro Val Arg Ser
                 725                 730                 735

 Cys Asp Asn Gly His Cys Met Leu Asn Gly Thr His Gly Pro Ser
                 740                 745                 750

 Ser Glu Lys Lys Ser Asn Ile Pro Asp Leu Ser Ile Tyr Leu Lys
                 755                 760                 765

 Gly Asp Val Phe Asp Ser Ala Ser Asp Pro Val Pro Leu Pro Pro
                 770                 775                 780

 Ala Arg Pro Pro Thr Arg Asp Asn Pro Lys His Gly Ser Ser Leu
                 785                 790                 795

 Asn Arg Thr Pro Ser Asp Tyr Asp Leu Leu Ile Pro Pro Leu Gly
                 800                 805                 810

 Glu Asp Ala Phe Asp Ala Leu Pro Pro Ser Leu Pro Pro Pro Pro
                 815                 820                 825

 Pro Pro Ala Arg His Ser Leu Ile Glu His Ser Lys Pro Pro Gly
                 830                 835                 840

 Ser Ser Ser Arg Pro Ser Ser Gly Gln Asp Leu Phe Leu Leu Pro
                 845                 850                 855

 Ser Asp Pro Phe Val Asp Leu Ala Ser Gly Gln Val Pro Leu Pro
                 860                 865                 870

 Pro Ala Arg Arg Leu Pro Gly Glu Asn Val Lys Thr Asn Arg Thr
                 875                 880                 885

 Ser Gln Asp Tyr Asp Gln Leu Pro Ser Cys Ser Asp Gly Ser Gln
                 890                 895                 900

 Ala Pro Ala Arg Pro Pro Lys Pro Arg Pro Arg Arg Thr Ala Pro
                 905                 910                 915

 Glu Ile His His Arg Lys Pro His Gly Pro Glu Ala Ala Leu Glu
                 920                 925                 930

 Asn Val Asp Ala Lys Ile Ala Lys Leu Met Gly Glu Gly Tyr Ala
                 935                 940                 945

 Phe Glu Glu Val Lys Arg Ala Leu Glu Ile Ala Gln Asn Asn Val
                 950                 955                 960

 Glu Val Ala Arg Ser Ile Leu Arg Glu Phe Ala Phe Pro Pro Pro
                 965                 970                 975

 Val Ser Pro Arg Leu Asn Leu
                 980

<210> 2072
<211> 836
<212> DNA
<213> Homo sapien

<400> 2072
 ccggtgagtc gccggcgctg cagagggagg cggcactggt ctcgacgtgg 50

 ggcggccagc gatgaagccg cccagttcaa tacaaacaag tgagtttgac 100

 tcatcagatg aagagcctat tgaagatgaa cagactccaa ttcatatatc 150

 atggctatct ttgtcacgag tgaattgttc tcagtttctc ggtttatgtg 200

 ctcttccagg ttgtaaattt aaagatgtta gaagaaatgt ccaaaaagat 250

 acagaagaac taaagagctg tggtatacaa gacatatttg ttttctgcac 300

 cagaggggaa ctgtcaaaat atagagtccc aaaccttctg gatctctacc 350

 agcaatgtgg aattatcacc catcatcatc caatcgcaga tggagggact 400

 cctgacatag ccagctgctg tgaaataatg gaagagctta caacctgcct 450

 taaaaattac cgaaaaacct taatacactg ctatggagga cttgggagat 500

 cttgtcttgt agctgcttgt ctcctactat acctgtctga cacaatatca 550

 ccagagcaag ccatagacag cctgcgagac ctaagaggat ccggggcaat 600

 acagaccatc aagcaataca attatcttca tgagtttcgg gacaaattag 650

 ctgcacatct atcatcaaga gattcacaat caagatctgt atcaagataa 700

 aggaattcaa atagcatata tatgaccatg tctgaaatgt cagttctcta 750

 gcataatttg tattgaaatg aaaccaccag tgttatcaac ttgaatgtaa 800

 atgtacatgt gcagatattc ctaaagtttt attgac 836

<210> 2073
<211> 212
<212> PRT
<213> Homo sapien

<400> 2073
 Met Lys Pro Pro Ser Ser Ile Gln Thr Ser Glu Phe Asp Ser Ser
   1               5                  10                  15

 Asp Glu Glu Pro Ile Glu Asp Glu Gln Thr Pro Ile His Ile Ser
                  20                  25                  30

 Trp Leu Ser Leu Ser Arg Val Asn Cys Ser Gln Phe Leu Gly Leu
                  35                  40                  45

 Cys Ala Leu Pro Gly Cys Lys Phe Lys Asp Val Arg Arg Asn Val
                  50                  55                  60

 Gln Lys Asp Thr Glu Glu Leu Lys Ser Cys Gly Ile Gln Asp Ile
                  65                  70                  75

 Phe Val Phe Cys Thr Arg Gly Glu Leu Ser Lys Tyr Arg Val Pro
                  80                  85                  90

 Asn Leu Leu Asp Leu Tyr Gln Gln Cys Gly Ile Ile Thr His His
                  95                 100                 105

 His Pro Ile Ala Asp Gly Gly Thr Pro Asp Ile Ala Ser Cys Cys
                 110                 115                 120

 Glu Ile Met Glu Glu Leu Thr Thr Cys Leu Lys Asn Tyr Arg Lys
                 125                 130                 135

 Thr Leu Ile His Cys Tyr Gly Gly Leu Gly Arg Ser Cys Leu Val
                 140                 145                 150

 Ala Ala Cys Leu Leu Leu Tyr Leu Ser Asp Thr Ile Ser Pro Glu
                 155                 160                 165

 Gln Ala Ile Asp Ser Leu Arg Asp Leu Arg Gly Ser Gly Ala Ile
                 170                 175                 180

 Gln Thr Ile Lys Gln Tyr Asn Tyr Leu His Glu Phe Arg Asp Lys
                 185                 190                 195

 Leu Ala Ala His Leu Ser Ser Arg Asp Ser Gln Ser Arg Ser Val
                 200                 205                 210

 Ser Arg


<210> 2074
<211> 3939
<212> DNA
<213> Homo sapien

<400> 2074
 cctgggtcct ctcggcgcca gagccgctct ccgcatccca ggacagcggt 50

 gcggccctcg gccggggcgc ccactccgca gcagccagcg agccagctgc 100

 cccgtatgac cgcgccgggc gccgccgggc gctgccctcc cacgacatgg 150

 ctgggctccc tgctgttgtt ggtctgtctc ctggcgagca ggagtatcac 200

 cgaggaggtg tcggagtact gtagccacat gattgggagt ggacacctgc 250

 agtctctgca gcggctgatt gacagtcaga tggagacctc gtgccaaatt 300

 acatttgagt ttgtagacca ggaacagttg aaagatccag tgtgctacct 350

 taagaaggca tttctcctgg tacaagacat aatggaggac accatgcgct 400

 tcagagataa caccgccaat cccatcgcca ttgtgcagct gcaggaactc 450

 tctttgaggc tgaagagctg cttcaccaag gattatgaag agcatgacaa 500

 ggcctgcgtc cgaactttct atgagacacc tctccagttg ctggagaagg 550

 tcaagaatgt ctttaatgaa acaaagaatc tccttgacaa ggactggaat 600

 attttcagca agaactgcaa caacagcttt gctgaatgct ccagccaaga 650

 tgtggtgacc aagcctgatt gcaactgcct gtaccccaaa gccatcccta 700

 gcagtgaccc ggcctctgtc tcccctcatc agcccctcgc cccctccatg 750

 gcccctgtgg ctggcttgac ctgggaggac tctgagggaa ctgagggcag 800

 ctccctcttg cctggtgagc agcccctgca cacagtggat ccaggcagtg 850

 ccaagcagcg gccacccagg agcacctgcc agagctttga gccgccagag 900

 accccagttg tcaaggacag caccatcggt ggctcaccac agcctcgccc 950

 ctctgtcggg gccttcaacc ccgggatgga ggatattctt gactctgcaa 1000

 tgggcactaa ttgggtccca gaagaagcct ctggagaggc cagtgagatt 1050

 cccgtacccc aagggacaga gctttccccc tccaggccag gagggggcag 1100

 catgcagaca gagcccgcca gacccagcaa cttcctctca gcatcttctc 1150

 cactccctgc atcagcaaag ggccaacagc cggcagatgt aactgctaca 1200

 gccttgccca gggtgggccc cgtgatgccc actggccagg actggaatca 1250

 caccccccag aagacagacc atccatctgc cctgctcaga gaccccccgg 1300

 agccaggctc tcccaggatc tcatcactgc gcccccaggc cctcagcaac 1350

 ccctccaccc tctctgctca gccacagctt tccagaagcc actcctcggg 1400

 cagcgtgctg ccccttgggg agctggaggg caggaggagc accagggatc 1450

 ggacgagccc cgcagagcca gaagcagcac cagcaagtga aggggcagcc 1500

 aggcccctgc cccgttttaa ctccgttcct ttgactgaca caggccatga 1550

 gaggcagtcc gagggatcct ccagcccgca gctccaggag tctgtcttcc 1600

 acctgctggt gcccagtgtc atcctggtct tgctggctgt cggaggcctc 1650

 ttgttctaca ggtggaggcg gcggagccat caagagcctc agagagcgga 1700

 ttctcccttg gagcaaccag agggcagccc cctgactcag gatgacagac 1750

 aggtggaact gccagtgtag agggaattct aagctggacg cacagaacag 1800

 tctcttcgtg ggaggagaca ttatggggcg tccaccacca cccctccctg 1850

 gccatcctcc tggaatgtgg tctgccctcc accagagctc ctgcctgcca 1900

 ggactggacc agagcagcca ggctggggcc cctctgtctc aacccgcaga 1950

 cccttgactg aatgagagag gccagaggat gctccccatg ctgccactat 2000

 ttattgtgag ccctggaggc tcccatgtgc ttgaggaagg ctggtgagcc 2050

 cggctcagga ccctcttccc tcaggggctg cagcctcctc tcactccctt 2100

 ccatgccgga acccaggcca gggacccacc ggcctgtggt ttgtgggaaa 2150

 gcagggtgca cgctgaggag tgaaacaacc ctgcacccag agggcctgcc 2200

 tggtgccaag gtatcccagc ctggacaggc atggacctgt ctccagacag 2250

 aggagcctga agttcgtggg gcgggacagc ctcggcctga tttcccgtaa 2300

 aggtgtgcag cctgagagac gggaagagga ggcctctgca cctgctggtc 2350

 tgcactgaca gcctgaaggg tctacaccct cggctcacct aagtccctgt 2400

 gctggttgcc aggcccagag gggaggccag ccctgccctc aggacctgcc 2450

 tgacctgcca gtgatgccaa gagggggatc aagcactggc ctctgcccct 2500

 cctccttcca gcacctgcca gagcttctcc agcaggccaa gcagaggctc 2550

 ccctcatgaa ggaagccatt gcactgtgaa cactgtacct gcctgctgaa 2600

 cagcctcccc ccgtccatcc atgagccagc atccgtccgt cctccactct 2650

 ccagcctctc cccagcctcc tgcactgagc tggcctcacc agtcgactga 2700

 gggagcccct cagccctgac cttctcctga cctggccttt gactccccgg 2750

 agtggagtgg ggtgggagaa cctcctgggc cgccagccag agccgctctt 2800

 taggctgtgt tcttcgccca ggtttctgca tcttccactt tgacattccc 2850

 aagagggaag ggactagtgg gagagagcaa gggaggggag ggcacagaca 2900

 gagagcctac agggcgagct ctgactgaag atgggccttt gaaatatagg 2950

 tatgcacctg aggttggggg agggtctgca ctcccaaacc ccagcgcagt 3000

 gtcctttccc tgctgccgac aggaacctgg ggctgagcag gttatccctg 3050

 tcaggagccc tggactgggc tgcatctcag ccccacctgc atggtatcca 3100

 gctcccatcc acttctcacc cttctttcct cctgaccttg gtcagcagtg 3150

 atgacctcca actctcaccc accccctcta ccatcacctc taaccaggca 3200

 agccagggtg ggagagcaat caggagagcc aggcctcagc ttccaatgcc 3250

 tggagggcct ccactttgtg gccagcctgt ggtgctggct ctgaggccta 3300

 ggcaacgagc gacagggctg ccagttgccc ctgggttcct ttgtgctgct 3350

 gtgtgcctcc tctcctgccg ccctttgtcc tccgctaaga gaccctgccc 3400

 tacctggccg ctgggccccg tgactttccc ttcctgccca ggaaagtgag 3450

 ggtcggctgg ccccaccttc cctgtcctga tgccgacagc ttagggaagg 3500

 gcactgaact tgcatatggg gcttagcctt ctagtcacag cctctatatt 3550

 tgatgctaga aaacacatat ttttaaatgg aagaaaaata aaaaggcatt 3600

 cccccttcat ccccctacct taaacatata atattttaaa ggtcaaaaaa 3650

 gcaatccaac ccactgcaga agctcttttt gagcacttgg tggcatcaga 3700

 gcaggaggag ccccagagcc acctctggtg tcccccaggc tacctgctca 3750

 ggaacccctt ctgttctctg agaactcaac agaggacatt ggctcacgca 3800

 ctgtgagatt ttgtttttat acttgcaact ggtgaattat tttttataaa 3850

 gtcatttaaa tatctattta aaagatagga agctgcttat atatttaata 3900

 ataaaagaag tgcacaagct gccgttgacg tagctcgag 3939

<210> 2075
<211> 554
<212> PRT
<213> Homo sapien

<400> 2075
 Met Thr Ala Pro Gly Ala Ala Gly Arg Cys Pro Pro Thr Thr Trp
   1               5                  10                  15

 Leu Gly Ser Leu Leu Leu Leu Val Cys Leu Leu Ala Ser Arg Ser
                  20                  25                  30

 Ile Thr Glu Glu Val Ser Glu Tyr Cys Ser His Met Ile Gly Ser
                  35                  40                  45

 Gly His Leu Gln Ser Leu Gln Arg Leu Ile Asp Ser Gln Met Glu
                  50                  55                  60

 Thr Ser Cys Gln Ile Thr Phe Glu Phe Val Asp Gln Glu Gln Leu
                  65                  70                  75

 Lys Asp Pro Val Cys Tyr Leu Lys Lys Ala Phe Leu Leu Val Gln
                  80                  85                  90

 Asp Ile Met Glu Asp Thr Met Arg Phe Arg Asp Asn Thr Ala Asn
                  95                 100                 105

 Pro Ile Ala Ile Val Gln Leu Gln Glu Leu Ser Leu Arg Leu Lys
                 110                 115                 120

 Ser Cys Phe Thr Lys Asp Tyr Glu Glu His Asp Lys Ala Cys Val
                 125                 130                 135

 Arg Thr Phe Tyr Glu Thr Pro Leu Gln Leu Leu Glu Lys Val Lys
                 140                 145                 150

 Asn Val Phe Asn Glu Thr Lys Asn Leu Leu Asp Lys Asp Trp Asn
                 155                 160                 165

 Ile Phe Ser Lys Asn Cys Asn Asn Ser Phe Ala Glu Cys Ser Ser
                 170                 175                 180

 Gln Asp Val Val Thr Lys Pro Asp Cys Asn Cys Leu Tyr Pro Lys
                 185                 190                 195

 Ala Ile Pro Ser Ser Asp Pro Ala Ser Val Ser Pro His Gln Pro
                 200                 205                 210

 Leu Ala Pro Ser Met Ala Pro Val Ala Gly Leu Thr Trp Glu Asp
                 215                 220                 225

 Ser Glu Gly Thr Glu Gly Ser Ser Leu Leu Pro Gly Glu Gln Pro
                 230                 235                 240

 Leu His Thr Val Asp Pro Gly Ser Ala Lys Gln Arg Pro Pro Arg
                 245                 250                 255

 Ser Thr Cys Gln Ser Phe Glu Pro Pro Glu Thr Pro Val Val Lys
                 260                 265                 270

 Asp Ser Thr Ile Gly Gly Ser Pro Gln Pro Arg Pro Ser Val Gly
                 275                 280                 285

 Ala Phe Asn Pro Gly Met Glu Asp Ile Leu Asp Ser Ala Met Gly
                 290                 295                 300

 Thr Asn Trp Val Pro Glu Glu Ala Ser Gly Glu Ala Ser Glu Ile
                 305                 310                 315

 Pro Val Pro Gln Gly Thr Glu Leu Ser Pro Ser Arg Pro Gly Gly
                 320                 325                 330

 Gly Ser Met Gln Thr Glu Pro Ala Arg Pro Ser Asn Phe Leu Ser
                 335                 340                 345

 Ala Ser Ser Pro Leu Pro Ala Ser Ala Lys Gly Gln Gln Pro Ala
                 350                 355                 360

 Asp Val Thr Ala Thr Ala Leu Pro Arg Val Gly Pro Val Met Pro
                 365                 370                 375

 Thr Gly Gln Asp Trp Asn His Thr Pro Gln Lys Thr Asp His Pro
                 380                 385                 390

 Ser Ala Leu Leu Arg Asp Pro Pro Glu Pro Gly Ser Pro Arg Ile
                 395                 400                 405

 Ser Ser Leu Arg Pro Gln Ala Leu Ser Asn Pro Ser Thr Leu Ser
                 410                 415                 420

 Ala Gln Pro Gln Leu Ser Arg Ser His Ser Ser Gly Ser Val Leu
                 425                 430                 435

 Pro Leu Gly Glu Leu Glu Gly Arg Arg Ser Thr Arg Asp Arg Thr
                 440                 445                 450

 Ser Pro Ala Glu Pro Glu Ala Ala Pro Ala Ser Glu Gly Ala Ala
                 455                 460                 465

 Arg Pro Leu Pro Arg Phe Asn Ser Val Pro Leu Thr Asp Thr Gly
                 470                 475                 480

 His Glu Arg Gln Ser Glu Gly Ser Ser Ser Pro Gln Leu Gln Glu
                 485                 490                 495

 Ser Val Phe His Leu Leu Val Pro Ser Val Ile Leu Val Leu Leu
                 500                 505                 510

 Ala Val Gly Gly Leu Leu Phe Tyr Arg Trp Arg Arg Arg Ser His
                 515                 520                 525

 Gln Glu Pro Gln Arg Ala Asp Ser Pro Leu Glu Gln Pro Glu Gly
                 530                 535                 540

 Ser Pro Leu Thr Gln Asp Asp Arg Gln Val Glu Leu Pro Val
                 545                 550

<210> 2076
<211> 7383
<212> DNA
<213> Homo sapien

<400> 2076
 ttctgcttat catggttacc aacaaaatga ctgctgcctt tagaaaccct 50

 agtgggaaac aggtggcgac agacaaagtt gcagaaaagc tgagctctac 100

 tctctcatgg gtgaagaaca cagtatcgca tacagtcagt cagatggcca 150

 gtcaggtggc aagtccatct acttcattac ataccacatc ctcatctacc 200

 acactatcaa caccagccct ttcaccatct tccccatcac agttgagtcc 250

 agacgtctta gaactcctgg ctaaactgga agaacagaat atattgttag 300

 aaacggatag taagtcttta agatctgtaa atgggtcaag aagaaacagt 350

 ggctcttctc ttgtgtcgag ttcatcagcc tctagcaacc tcagtcacct 400

 tgaagaagat tcttggattc tttggggaag aattgttaat gaatgggaag 450

 atgtacgcaa aaagaaggaa aagcaagtta aggaacttgt tcataaaggg 500

 ataccccatc actttagagc aatagtttgg caacttttat gcagtgcaca 550

 aagtatgcca attaaggatc agtattcaga actcctgaaa atgacctcgc 600

 cttgtgaaaa attgatccga agggacattg ctagaactta ccctgaacac 650

 aactttttta aggaaaaaga tagccttgga caggaggttt tatttaatgt 700

 aatgaaggct tactctttag tagatcgtga ggttggttac tgtcaaggaa 750

 gtgcttttat agttggattg ttgcttatgc agatgccaga agaagaagct 800

 ttctgtgtat ttgttaaatt aatgcaagat tatagacttc gtgaactttt 850

 taaaccaagt atggcagaat tgggcctttg tatgtaccag tttgaatgta 900

 tgatacagga gcatcttcca gagctctttg tacattttca atctcagagt 950

 tttcatacct caatgtatgc atcatcctgg tttctgacta tctttcttac 1000

 aacttttcca ctaccagttg caacaaggat atttgatatc tttatgtctg 1050

 agggtttaga aatagtgttt cgtgtaggat tagcacttct tcagatgaat 1100

 caggcagaac tgatgcaact tgacatggaa gggatgttac agcactttca 1150

 aaaggtcatt ccacatcagt ttgatggtgt cccagacaag ctaatccaag 1200

 cagcttacca agtccaatac aattcaaaaa aaatgaaaaa gcttgaaaag 1250

 gaatacacta caataaaaac gaaagaaatg gaagagcaag ttgaaattaa 1300

 aaggttacgc acagaaaata gacttttaaa acagcgcatc gagacattag 1350

 aaaaacataa atgcagttcc aactacaacg aagattttgt gctacagcta 1400

 gagaaggaat tggtccaagc ccgactgagt gaagctgagt ctcagtgtgc 1450

 attaaaagag atgcaggata aagtcttgga tatagagaag aggaataact 1500

 cccttcctga tgagaataat attgcaaggc ttcaggaaga actcattgct 1550

 gtgaaactta gagaagcaga agccattatg ggtttgaaag aacttagaca 1600

 gcaagtcaag gatttagagg aacactggca gcgccactta gctcgtacta 1650

 ctgggagatg gaaagaccca cccaagaaaa atgctatgaa tgagttacag 1700

 gatgaactga tgaccattcg acttagagaa gctgaaacac aagcagaaat 1750

 aagagaaata aaacaaagga tgatggaaat ggaaacacag aaccagatca 1800

 atagtaacca tcttcgaaga gcagaacaag aggtgattag cctacaggag 1850

 aaagtgcagt atctttctgc acagaacaaa ggactcctta ctcaattaag 1900

 tgaagcaaag cgtaaacaag cagagattga atgcaagaat aaggaagaag 1950

 tgatggctgt gaggcttcgg gaagcagata gcatagctgc tgtggctgaa 2000

 ctacgacaac acattgctga gcttgaaatc cagaaagaag aaggaaagct 2050

 tcaaggacag cttaacaagt ctgattctaa ccagtatatt ggggaactga 2100

 aagatcagat agcagagctg aatcatgagc tcaggtgcct aaaaggccag 2150

 aagggcttct caggccaacc tccttttgat ggaatccaca ttgtcaacca 2200

 tttaatagga gatgatgaat cattccattc ctccgatgaa gattttatag 2250

 ataattcctt acaggaaact ggtgttggtt ttcctttgca cggaaaatct 2300

 ggctcgatgt ctttggaccc cgcagtggca gatggtagtg agagcgaaac 2350

 agaagacagt gtgctggaga ccagagagag caaccaagtg gttcaaaagg 2400

 agcggccccc gagaagaaga gagtcgtatt caaccactgt ctgaccatca 2450

 ctgtgaccta gactatggat ttatttaagg gatcagttat catatgatta 2500

 gggctttttg gaaataattt gttttcatat gtatatatat atatatatat 2550

 atatatttta cagtcttatc tgccttttta tctttgccaa atctttacca 2600

 ctgatttacc attgccataa agtagactgg tatatggtta atgtgtaaaa 2650

 caaggttcta acagtattac tgaatattaa tgtttcttgt ttagaaaatg 2700

 caactatatc tatatgtggg aaccatttct gaagttcaaa actatggaaa 2750

 attgaatttt cttcaaacaa aactgctctt gtgcaatatt ttatgctcag 2800

 tgagcaaatt gtgtatttat gtttatcaat ttgttcccca ggtggctgtc 2850

 tacaaacatt tgaccaaaac atacatttga attaccttgg gttttttttt 2900

 attggtgttt tttttttaag acagagattc agtttgtcac ccaggctgga 2950

 gtgctgtggt gtgattttag ttcactgcaa cttccgcttc ccaggttcaa 3000

 gcaattttcc tgcttcagct tcccgagtac ctgggactat atgtgcgcac 3050

 caccacgcct ggctaatttt ttgtattttt agtagagatg gggtttcacc 3100

 atgttggctg ggctggtctc gaactcctaa cctcaagtga tccacccgcc 3150

 tcagcctccc aaagtgctgg gattacaggt gtgagccact gcacccagcc 3200

 taccttgtct gtttgtgtct gggaggtttt ttttttctat ttttattttt 3250

 tcatgaaaat tattggtggg ccactgaaag tccccacaca caaagccttt 3300

 attctatata attttataaa cacaaattca tgattatctg ttttgagagt 3350

 tttaagtttt gttttaatgt ttaactttta tgtgcatatg atgctttcca 3400

 tgtgttggtt actagagtag taggttaact acagacatac tgttttgttt 3450

 gtacatattt ataaatctgt accacctaac attgaacatc attttatatg 3500

 aagaacatac atgttgcaaa atgactgctt tcagcatcta acaggacttc 3550

 tgtaaataat aggttaaaag ttaaaaataa aacactaatg ttttaagagc 3600

 tttagtattt tgcttagcat tcaatactag cagattcata actgatgcct 3650

 gttcaaaaac actgttggtg gaatctttta tttcatgtgt atgtaactac 3700

 taaatttttc atgactgaag aggttatagc acatattagt tagtgctaat 3750

 attctactga atataattta agcaatgggc taaggtccaa gaaacatagc 3800

 aattatatct acaaataatc tattaacatg atcttcagaa tctctagttt 3850

 ttgttctata gataaagcca taagaatcct ttcctaccag tttttcctat 3900

 atcatttaga tattatttcc tagaaaacag gatgcctgtc actgataagt 3950

 tagagaaaac acccaaatta tacttgcact atggaaagac gacatggatt 4000

 tgttgtctgg gtactttcta ctctcatttt tgttagccta tgaaaaaaaa 4050

 aaacattttg ttaacctatg gaaaaagcct tggaagagaa aagtagaatt 4100

 cagtatgtat ggaggcacag ttttgcacag tatgttgcat gcggcaaaaa 4150

 aaaaaatatg aaatagagta gaagagataa aagtagtttt ctgtcaaaaa 4200

 ctaggagtta agccttcagg tacgttgtgg actaggcttt ccagcaaggt 4250

 ttttgtagct atttgcttgc ctgagaaatg aaattgaaaa catacccctg 4300

 cgtgtctgtc cttaacacca ggctaaattc tggtggttaa ataacttacc 4350

 tgtggttaca agctagtaag tagcagagcc aagatttttt ttaatataga 4400

 gacaggtgtc tcactgtgtt gtccaggctg gtcttgaact cctggcctca 4450

 agtggtcctc ctgcctcagc ctcccaaagt gtggggatta caggtgcgag 4500

 ctactgctcc cagcaagagc caagatttta acctagatct ccctaacacc 4550

 aaagcttttg aaagggtttc agctgaagaa tttcttcaat tcttctgttt 4600

 tgtttttatt tttgtttttt gagatgaagt ctcactgcac tcaggctgga 4650

 gtgcagtggt acgatcttgg ctcactgcaa cttccacttc ccgggttcaa 4700

 gcgattctcc tgcctcagct cccaagtagc tgggactaca ggtgcacgcc 4750

 accacaactg gctaattttt gtatttttag tagagatggg gtttcgctat 4800

 gttggccagg ctgatctcaa acttctgacc tcaggtgatc cacccacttt 4850

 gacctcccaa agtgctggga ttactagacg taagccacca cacctggcaa 4900

 ttccctgctt ttttgacaac ataatttaaa tgaatttgat ttaaatgttt 4950

 cctgaatata tatacagata gatagatgag tatcaacact tacaagctct 5000

 acacagtctg tgagtgtaga tactacttac ttgtaggatt gtcttgtgct 5050

 ttggggattt ttgttcggag ttctatacta tcagcccaga aagctatcaa 5100

 tgtccaagtg aagtgagatg atgcatgcca cattattgct ttgaccttca 5150

 catcaagaaa tctgaatgat ctggaccagg gtcagcaaag tgcagcctac 5200

 aagttattgc agtcagctgc cagtttttac ttttttaaat agttgggaaa 5250

 aaaattccaa agactgatat tttgtgtcac atgaaaatta tatgaaattc 5300

 aaattgcagt gtccataagt aaagttttat tggggcacac ccatgctcac 5350

 ccttttaaat attgtgtatg gccgctttgt gctacagtag cagagttgag 5400

 tcattgcaag ggagaccata tggcccaggt agcctaaata tttatctgat 5450

 cctttacaga aaaagtttgc taacccttga taacagatac tctaaaatgc 5500

 aggtttttct tcttcagttt agctcagtgg taggtcaatt gtttgctttt 5550

 gctattaagc ttatgatttg gaaacgtaaa attttcatgg tggatcttat 5600

 aatcagaact attcaaaagg gaaaacatgc cagccatttt atatgatgaa 5650

 gtctcttatt ccatagaaaa ctgtagaaag gtatctgtat ctttggagaa 5700

 ggagaaagaa aggaaagaac tccagaatcc catcactgtt ctttaaagca 5750

 tgcatcacag acctttaaga gtatgcttta ttgagtaaag gttatagttt 5800

 gactttaaga taagaaattt tctagaatca tgtttgaatt ctaaacgttg 5850

 atattcttaa gtaccatttc tgattaggaa ttaggtgtta aaagaatcat 5900

 ggtaaggaaa ccttaatccg ttgaaactct tgtaatttgg acaacaaaaa 5950

 actagaaata acactctttt ctttgaagat ctgattcaaa tacaccttag 6000

 aagagtttaa aatctcccag gcctttagga tgcaatagga tattatgcct 6050

 tggtttgact ccttttcatt caaattaatg taagtatgtt gttcaagact 6100

 ttgaagcatt gaacaatgtt ctcgacgaat tttatttaat tactgacatt 6150

 ttgtgatatt tgaatgttat taagttaaac acttagagtt gagtatattc 6200

 aggggagaaa agtgaatgaa atgactcata ataagaaagc ttgctccctt 6250

 gggacagtta ccttcctggt gtcattgcca tcctgggttg acaagctgag 6300

 agtagaggat acaagtgatg tgaataaaat ggaaattgca ttgagttaat 6350

 gaaacataca cttttagatc aagataacat tcaacagcct ttttagaaat 6400

 tgcacactcc tatagtccca cttactcaag gaggtggggg cagggaggat 6450

 cactggagta caggagtttg gggctgtagt gtgtaatgat caacacctgt 6500

 gaaagaataa ccactgcact ccaacctggg caacatggca agaccctgtc 6550

 tctttaaaaa aaaaaaaaaa tcctgggaaa agaagtcaaa gatgtaattt 6600

 tacacaattt ctgcccccac cgtctttttt gtttgtttgt ttgtttgttt 6650

 gttttttggc tagatactag gtattcagtg tttgctgaga tgacaggttt 6700

 ctactaatca gccagttatt tgggaaggag aaaaactttt tctcaattct 6750

 gaacatgatg cagcttgtta actctccaga tagtgccttt gattgaaaat 6800

 aaggtctaca cctttttaag tatattattt ctgacatcgt aagaaataat 6850

 ttagttcctt attctcattt atcttttata taatgtactg taatattcag 6900

 gtttaaagta aaataagtat atggaattat attttggtaa aactgtttca 6950

 tgaccagctt gattaatgta tattaacata ccagacattg acagcgaaca 7000

 tttcatgaaa tcagttattt acttactaaa acaatgagtt ttagcttgaa 7050

 agttactgct gctctattat taacaaaact aagttttaaa aattaatttt 7100

 aattctactg aagtttaatt tctggttaaa ggtatagtgg atgctattta 7150

 tgatccaagt ttttacatca catccattga tctgcctatc ccttcttttt 7200

 actccaaaga ggagatgata gaataataca ttcagtatac taccaagaag 7250

 caaagttata atgtgtttca ttttgctatt ggaatttttt attgtaacat 7300

 tgtatgataa cctgaaatgt ttacttgtgc cttttcttta aacaattaaa 7350

 gttttccatt ttataagaaa caaaaaaaaa aaa 7383

<210> 2077
<211> 810
<212> PRT
<213> Homo sapien

<400> 2077
 Met Val Thr Asn Lys Met Thr Ala Ala Phe Arg Asn Pro Ser Gly
   1               5                  10                  15

 Lys Gln Val Ala Thr Asp Lys Val Ala Glu Lys Leu Ser Ser Thr
                  20                  25                  30

 Leu Ser Trp Val Lys Asn Thr Val Ser His Thr Val Ser Gln Met
                  35                  40                  45

 Ala Ser Gln Val Ala Ser Pro Ser Thr Ser Leu His Thr Thr Ser
                  50                  55                  60

 Ser Ser Thr Thr Leu Ser Thr Pro Ala Leu Ser Pro Ser Ser Pro
                  65                  70                  75

 Ser Gln Leu Ser Pro Asp Val Leu Glu Leu Leu Ala Lys Leu Glu
                  80                  85                  90

 Glu Gln Asn Ile Leu Leu Glu Thr Asp Ser Lys Ser Leu Arg Ser
                  95                 100                 105

 Val Asn Gly Ser Arg Arg Asn Ser Gly Ser Ser Leu Val Ser Ser
                 110                 115                 120

 Ser Ser Ala Ser Ser Asn Leu Ser His Leu Glu Glu Asp Ser Trp
                 125                 130                 135

 Ile Leu Trp Gly Arg Ile Val Asn Glu Trp Glu Asp Val Arg Lys
                 140                 145                 150

 Lys Lys Glu Lys Gln Val Lys Glu Leu Val His Lys Gly Ile Pro
                 155                 160                 165

 His His Phe Arg Ala Ile Val Trp Gln Leu Leu Cys Ser Ala Gln
                 170                 175                 180

 Ser Met Pro Ile Lys Asp Gln Tyr Ser Glu Leu Leu Lys Met Thr
                 185                 190                 195

 Ser Pro Cys Glu Lys Leu Ile Arg Arg Asp Ile Ala Arg Thr Tyr
                 200                 205                 210

 Pro Glu His Asn Phe Phe Lys Glu Lys Asp Ser Leu Gly Gln Glu
                 215                 220                 225

 Val Leu Phe Asn Val Met Lys Ala Tyr Ser Leu Val Asp Arg Glu
                 230                 235                 240

 Val Gly Tyr Cys Gln Gly Ser Ala Phe Ile Val Gly Leu Leu Leu
                 245                 250                 255

 Met Gln Met Pro Glu Glu Glu Ala Phe Cys Val Phe Val Lys Leu
                 260                 265                 270

 Met Gln Asp Tyr Arg Leu Arg Glu Leu Phe Lys Pro Ser Met Ala
                 275                 280                 285

 Glu Leu Gly Leu Cys Met Tyr Gln Phe Glu Cys Met Ile Gln Glu
                 290                 295                 300

 His Leu Pro Glu Leu Phe Val His Phe Gln Ser Gln Ser Phe His
                 305                 310                 315

 Thr Ser Met Tyr Ala Ser Ser Trp Phe Leu Thr Ile Phe Leu Thr
                 320                 325                 330

 Thr Phe Pro Leu Pro Val Ala Thr Arg Ile Phe Asp Ile Phe Met
                 335                 340                 345

 Ser Glu Gly Leu Glu Ile Val Phe Arg Val Gly Leu Ala Leu Leu
                 350                 355                 360

 Gln Met Asn Gln Ala Glu Leu Met Gln Leu Asp Met Glu Gly Met
                 365                 370                 375

 Leu Gln His Phe Gln Lys Val Ile Pro His Gln Phe Asp Gly Val
                 380                 385                 390

 Pro Asp Lys Leu Ile Gln Ala Ala Tyr Gln Val Gln Tyr Asn Ser
                 395                 400                 405

 Lys Lys Met Lys Lys Leu Glu Lys Glu Tyr Thr Thr Ile Lys Thr
                 410                 415                 420

 Lys Glu Met Glu Glu Gln Val Glu Ile Lys Arg Leu Arg Thr Glu
                 425                 430                 435

 Asn Arg Leu Leu Lys Gln Arg Ile Glu Thr Leu Glu Lys His Lys
                 440                 445                 450

 Cys Ser Ser Asn Tyr Asn Glu Asp Phe Val Leu Gln Leu Glu Lys
                 455                 460                 465

 Glu Leu Val Gln Ala Arg Leu Ser Glu Ala Glu Ser Gln Cys Ala
                 470                 475                 480

 Leu Lys Glu Met Gln Asp Lys Val Leu Asp Ile Glu Lys Arg Asn
                 485                 490                 495

 Asn Ser Leu Pro Asp Glu Asn Asn Ile Ala Arg Leu Gln Glu Glu
                 500                 505                 510

 Leu Ile Ala Val Lys Leu Arg Glu Ala Glu Ala Ile Met Gly Leu
                 515                 520                 525

 Lys Glu Leu Arg Gln Gln Val Lys Asp Leu Glu Glu His Trp Gln
                 530                 535                 540

 Arg His Leu Ala Arg Thr Thr Gly Arg Trp Lys Asp Pro Pro Lys
                 545                 550                 555

 Lys Asn Ala Met Asn Glu Leu Gln Asp Glu Leu Met Thr Ile Arg
                 560                 565                 570

 Leu Arg Glu Ala Glu Thr Gln Ala Glu Ile Arg Glu Ile Lys Gln
                 575                 580                 585

 Arg Met Met Glu Met Glu Thr Gln Asn Gln Ile Asn Ser Asn His
                 590                 595                 600

 Leu Arg Arg Ala Glu Gln Glu Val Ile Ser Leu Gln Glu Lys Val
                 605                 610                 615

 Gln Tyr Leu Ser Ala Gln Asn Lys Gly Leu Leu Thr Gln Leu Ser
                 620                 625                 630

 Glu Ala Lys Arg Lys Gln Ala Glu Ile Glu Cys Lys Asn Lys Glu
                 635                 640                 645

 Glu Val Met Ala Val Arg Leu Arg Glu Ala Asp Ser Ile Ala Ala
                 650                 655                 660

 Val Ala Glu Leu Arg Gln His Ile Ala Glu Leu Glu Ile Gln Lys
                 665                 670                 675

 Glu Glu Gly Lys Leu Gln Gly Gln Leu Asn Lys Ser Asp Ser Asn
                 680                 685                 690

 Gln Tyr Ile Gly Glu Leu Lys Asp Gln Ile Ala Glu Leu Asn His
                 695                 700                 705

 Glu Leu Arg Cys Leu Lys Gly Gln Lys Gly Phe Ser Gly Gln Pro
                 710                 715                 720

 Pro Phe Asp Gly Ile His Ile Val Asn His Leu Ile Gly Asp Asp
                 725                 730                 735

 Glu Ser Phe His Ser Ser Asp Glu Asp Phe Ile Asp Asn Ser Leu
                 740                 745                 750

 Gln Glu Thr Gly Val Gly Phe Pro Leu His Gly Lys Ser Gly Ser
                 755                 760                 765

 Met Ser Leu Asp Pro Ala Val Ala Asp Gly Ser Glu Ser Glu Thr
                 770                 775                 780

 Glu Asp Ser Val Leu Glu Thr Arg Glu Ser Asn Gln Val Val Gln
                 785                 790                 795

 Lys Glu Arg Pro Pro Arg Arg Arg Glu Ser Tyr Ser Thr Thr Val
                 800                 805                 810

<210> 2078
<211> 759
<212> DNA
<213> Homo sapien

<400> 2078
 ctgtgctgta aaaacaagag taacattttt atattaaagt taaataaagt 50

 tacaactttg aagagagttt ctgcaagaca tgacacaaag ctgctagcag 100

 aaaatcaaaa cgctgattaa aagaagcacg gtatgatgac caaacataaa 150

 aagtgtttta taattgttgg tgttttaata acaactaata ttattactct 200

 gatagttaaa ctaactcgag attctcagag tttatgcccc tatgattgga 250

 ttggtttcca aaacaaatgc tattatttct ctaaagaaga aggagattgg 300

 aattcaagta aatacaactg ttccactcaa catgccgacc taactataat 350

 tgacaacata gaagaaatga attttcttag gcggtataaa tgcagttctg 400

 atcactggat tggactgaag atggcaaaaa atcgaacagg acaatgggta 450

 catggagcta catttaccaa atcgtttggc atgagaggga gtgaaggatg 500

 tgcctacctc agcgatgatg gtgcagcaac agctagatgt tacaccgaaa 550

 gaaaatggat ttgcaggaaa agaatacact aagttaatgt ctaagataat 600

 ggggaaaata gaaaataaca ttattaagtg taaaaccagc aaagtacttt 650

 tttaattaaa caaagttcga gttttgtacc tgtctggtta attctgctta 700

 cgtgtcaggc tacacataaa agccacttca aagattggca aaaaaaaaaa 750

 aaaaaaaaa 759

<210> 2079
<211> 149
<212> PRT
<213> Homo sapien

<400> 2079
 Met Met Thr Lys His Lys Lys Cys Phe Ile Ile Val Gly Val Leu
   1               5                  10                  15

 Ile Thr Thr Asn Ile Ile Thr Leu Ile Val Lys Leu Thr Arg Asp
                  20                  25                  30

 Ser Gln Ser Leu Cys Pro Tyr Asp Trp Ile Gly Phe Gln Asn Lys
                  35                  40                  45

 Cys Tyr Tyr Phe Ser Lys Glu Glu Gly Asp Trp Asn Ser Ser Lys
                  50                  55                  60

 Tyr Asn Cys Ser Thr Gln His Ala Asp Leu Thr Ile Ile Asp Asn
                  65                  70                  75

 Ile Glu Glu Met Asn Phe Leu Arg Arg Tyr Lys Cys Ser Ser Asp
                  80                  85                  90

 His Trp Ile Gly Leu Lys Met Ala Lys Asn Arg Thr Gly Gln Trp
                  95                 100                 105

 Val His Gly Ala Thr Phe Thr Lys Ser Phe Gly Met Arg Gly Ser
                 110                 115                 120

 Glu Gly Cys Ala Tyr Leu Ser Asp Asp Gly Ala Ala Thr Ala Arg
                 125                 130                 135

 Cys Tyr Thr Glu Arg Lys Trp Ile Cys Arg Lys Arg Ile His
                 140                 145

<210> 2080
<211> 1368
<212> DNA
<213> Homo sapien

<400> 2080
 cctgctttgc cgaagtggga gaaaaaacag aggaaagaag agtagaaagg 50

 gatattctta aggaaatgtt cccctatgaa gcatctacac caacaggaat 100

 tagtgctagt tgccgcagac caatcaaagg ggctgcaggc cggccattag 150

 aactcagtga tttcaggatg gaggagtctt tttcatctaa atatgttcct 200

 aagtatgttc ccttggcaga tgtcaagtca gaaaagacaa aaaagggacg 250

 ctccattccc gtatggataa aaattttgct gtttgttgtt gtggcagttt 300

 ttttgttttt ggtctatcaa gctatggaaa ccaaccaagt aaatcccttc 350

 tctaattttc ttcatgttga ccctagaaaa tccaactgaa tggtatctct 400

 ttggcacgtt caacttggtc tcctattttc aataactgtt gaaaaacatt 450

 tgtgtacact tgttgactcc aagaactaaa aataatgtga tttcgcctca 500

 ataaatgtag tatttcattg aaaagcaaac aaaatatata taaatggact 550

 tcattaaaat gtttttgaac tttggactag taggagatca ctttgtgcca 600

 tatgaataat cttttttagc tctggaactt tttgtaggct ttattttttt 650

 aatgtgggca tcttatttca tttttgaaaa aatgtatatg ttttttgtgt 700

 atttgggaaa cgaagggtga aacatggtag tataatgtga agctacacat 750

 ttaaatactt agaattctta cagaaaagat tttaagaatt attctctgct 800

 gaataaaaac tgcaaatatg tgaaacataa tgaaattcag taagaggaaa 850

 agtaacttgg ttgtactttt tgtaactgca acaaagtttg atggtgttta 900

 tgaggaaaag tacagcaata atctcttctg taacctttat taatagtaat 950

 gttgttgtag ccctatcata ctcacttttt aagacacagt atcatgaaag 1000

 tcctatttca gtaagaccca tttacataca gtagattttt agcagagatc 1050

 ttttagtgta acatacatat tttagagaat tgttggctag ctgtacatgt 1100

 tttgaaaagc tgtttagcta gctataaggc tataattgga aatttgtatt 1150

 ttttatttac agcaaaacat ttattcagtc atccagtttg ctaccaaaat 1200

 atgttttaga taagtgtgtg tatgtttgtt tagaagttag aaattgtaaa 1250

 cactggtctt atgtttcatt tggattcatt attgcattgt cttgttacca 1300

 gaaacaaatt ttgccgagct tttttgccct atatttccca gcataatttg 1350

 attaaaaaaa aaaaaaaa 1368

<210> 2081
<211> 107
<212> PRT
<213> Homo sapien

<400> 2081
 Met Phe Pro Tyr Glu Ala Ser Thr Pro Thr Gly Ile Ser Ala Ser
   1               5                  10                  15

 Cys Arg Arg Pro Ile Lys Gly Ala Ala Gly Arg Pro Leu Glu Leu
                  20                  25                  30

 Ser Asp Phe Arg Met Glu Glu Ser Phe Ser Ser Lys Tyr Val Pro
                  35                  40                  45

 Lys Tyr Val Pro Leu Ala Asp Val Lys Ser Glu Lys Thr Lys Lys
                  50                  55                  60

 Gly Arg Ser Ile Pro Val Trp Ile Lys Ile Leu Leu Phe Val Val
                  65                  70                  75

 Val Ala Val Phe Leu Phe Leu Val Tyr Gln Ala Met Glu Thr Asn
                  80                  85                  90

 Gln Val Asn Pro Phe Ser Asn Phe Leu His Val Asp Pro Arg Lys
                  95                 100                 105

 Ser Asn


<210> 2082
<211> 2374
<212> DNA
<213> Homo sapien

<400> 2082
 ggttggtgcg agcttccagc ttggccgcag ttggttcgta gttcggctct 50

 ggggtctttt gtgtccgggt ctggcttggc tttgtgtccg cgagtttttg 100

 ttccgctccg cagcgctctt cccgggcagg agccgtgagg ctcggaggcg 150

 gcagcgcggt ccccggccag gagcaagcgc gccggcgtga gcggcggcgg 200

 caaaggctgt ggggaggggg cttcgcagat ccccgagatg ccggagttcc 250

 tggaagaccc ctcggtcctg acaaaagaca agttgaagag tgagttggtc 300

 gccaacaatg tgacgctgcc ggccggggag cagcgcaaag acgtgtacgt 350

 ccagctctac ctgcagcacc tcacggctcg caaccggccg ccgctccccg 400

 ccggcaccaa cagcaagggg cccccggact tctccagtga cgaagagcgc 450

 gagcccaccc cggtcctcgg ctctggggcc gccgccgcgg gccggagccg 500

 agcagccgtc ggcaggaaag ccacaaaaaa aactgataaa cccagacaag 550

 aagataaaga tgatctagat gtaacagagc tcactaatga agatcttttg 600

 gatcagcttg tgaaatacgg agtgaatcct ggtcctattg tgggaacaac 650

 caggaagcta tatgagaaaa agcttttgaa actgagggaa caaggaacag 700

 aatcaagatc ttctactcct ctgccaacaa tttcttcttc agcagaaaat 750

 acaaggcaga atggaagtaa tgattctgac agatacagtg acaatgaaga 800

 agactctaaa atagagctca agcttgagaa gagagaacca ctaaagggca 850

 gagcaaagac tccagtaaca ctcaagcaaa gaagagttga gcacaatcag 900

 gtgggagaaa aaacagagga aagaagagta gaaagggata ttcttaagga 950

 aatgttcccc tatgaagcat ctacaccaac aggaattagt gctagttgcc 1000

 gcagaccaat caaaggggct gcaggccggc cattagaact cagtgatttc 1050

 aggatggagg agtctttttc atctaaatat gttcctaagt atgttccctt 1100

 ggcagatgtc aagtcagaaa agacaaaaaa gggacgctcc attcccgtat 1150

 ggataaaaat tttgctgttt gttgttgtgg cagttttttt gtttttggtc 1200

 tatcaagcta tggaaaccaa ccaagtaaat cccttctcta attttcttca 1250

 tgttgaccct agaaaatcca actgaatggt atctctttgg cacgttcaac 1300

 ttggtctcct attttcaata actgttgaaa aacatttgtg tacacttgtt 1350

 gactccaaga actaaaaata atgtgatttc gcctcaataa atgtagtatt 1400

 tcattgaaaa gcaaacaaaa tatatataaa tggacttcat taaaatgttt 1450

 ttgaactttg gactagtagg agatcacttt gtgccatatg aataatcttt 1500

 tttagctctg gaactttttg taggctttat ttttttaatg tgggcatctt 1550

 atttcatttt tgaaaaaatg tatatgtttt ttgtgtattt gggaaacgaa 1600

 gggtgaaaca tggtagtata atgtgaagct acacatttaa atacttagaa 1650

 ttcttacaga aaagatttta agaattattc tctgctgaat aaaaactgca 1700

 aatatgtgaa acataatgaa attcagtaag aggaaaagta acttggttgt 1750

 actttttgta actgcaacaa agtttgatgg tgtttatgag gaaaagtaca 1800

 gcaataatct cttctgtaac ctttattaat agtaatgttg ttgtagccct 1850

 atcatactca ctttttaaga cacagtatca tgaaagtcct atttcagtaa 1900

 gacccattta catacagtag atttttagca gagatctttt agtgtaacat 1950

 acatatttta gagaattgtt ggctagctgt acatgttttg aaaagctgtt 2000

 tagctagcta taaggctata attggaaatt tgtatttttt atttacagca 2050

 aaacatttat tcagtcatcc agtttgctac caaaatatgt tttagataag 2100

 tgtgtgtatg tttgtttaga agttagaaat tgtaaacact ggtcttatgt 2150

 ttcatttgga ttcattattg cattgtcttg ttaccagaaa caaattttgc 2200

 cgagcttttt ttgccctata tttcccagca taatttgatt agaaagtaca 2250

 aaaagggccg ggcgcggtgg cttacgcctg taatcccagc actttgggag 2300

 gccagggcgg gtggatcacg aggtcaggag atcgggacca tcctggccaa 2350

 catggtgaaa ccccgtctct acta 2374

<210> 2083
<211> 345
<212> PRT
<213> Homo sapien

<400> 2083
 Met Pro Glu Phe Leu Glu Asp Pro Ser Val Leu Thr Lys Asp Lys
   1               5                  10                  15

 Leu Lys Ser Glu Leu Val Ala Asn Asn Val Thr Leu Pro Ala Gly
                  20                  25                  30

 Glu Gln Arg Lys Asp Val Tyr Val Gln Leu Tyr Leu Gln His Leu
                  35                  40                  45

 Thr Ala Arg Asn Arg Pro Pro Leu Pro Ala Gly Thr Asn Ser Lys
                  50                  55                  60

 Gly Pro Pro Asp Phe Ser Ser Asp Glu Glu Arg Glu Pro Thr Pro
                  65                  70                  75

 Val Leu Gly Ser Gly Ala Ala Ala Ala Gly Arg Ser Arg Ala Ala
                  80                  85                  90

 Val Gly Arg Lys Ala Thr Lys Lys Thr Asp Lys Pro Arg Gln Glu
                  95                 100                 105

 Asp Lys Asp Asp Leu Asp Val Thr Glu Leu Thr Asn Glu Asp Leu
                 110                 115                 120

 Leu Asp Gln Leu Val Lys Tyr Gly Val Asn Pro Gly Pro Ile Val
                 125                 130                 135

 Gly Thr Thr Arg Lys Leu Tyr Glu Lys Lys Leu Leu Lys Leu Arg
                 140                 145                 150

 Glu Gln Gly Thr Glu Ser Arg Ser Ser Thr Pro Leu Pro Thr Ile
                 155                 160                 165

 Ser Ser Ser Ala Glu Asn Thr Arg Gln Asn Gly Ser Asn Asp Ser
                 170                 175                 180

 Asp Arg Tyr Ser Asp Asn Glu Glu Asp Ser Lys Ile Glu Leu Lys
                 185                 190                 195

 Leu Glu Lys Arg Glu Pro Leu Lys Gly Arg Ala Lys Thr Pro Val
                 200                 205                 210

 Thr Leu Lys Gln Arg Arg Val Glu His Asn Gln Val Gly Glu Lys
                 215                 220                 225

 Thr Glu Glu Arg Arg Val Glu Arg Asp Ile Leu Lys Glu Met Phe
                 230                 235                 240

 Pro Tyr Glu Ala Ser Thr Pro Thr Gly Ile Ser Ala Ser Cys Arg
                 245                 250                 255

 Arg Pro Ile Lys Gly Ala Ala Gly Arg Pro Leu Glu Leu Ser Asp
                 260                 265                 270

 Phe Arg Met Glu Glu Ser Phe Ser Ser Lys Tyr Val Pro Lys Tyr
                 275                 280                 285

 Val Pro Leu Ala Asp Val Lys Ser Glu Lys Thr Lys Lys Gly Arg
                 290                 295                 300

 Ser Ile Pro Val Trp Ile Lys Ile Leu Leu Phe Val Val Val Ala
                 305                 310                 315

 Val Phe Leu Phe Leu Val Tyr Gln Ala Met Glu Thr Asn Gln Val
                 320                 325                 330

 Asn Pro Phe Ser Asn Phe Leu His Val Asp Pro Arg Lys Ser Asn
                 335                 340                 345

<210> 2084
<211> 2431
<212> DNA
<213> Homo sapien

<400> 2084
 gttttgcctg ctagcatctc cctgtaactc tcccaatctt gaggagtgat 50

 ccctgtccca gcccctggaa aggggcagga acgacaaact caaagtccag 100

 gatgttcacc atgacaagag ccatggaaga ggctcttttt cagcacttca 150

 tgcaccagaa gctggggatc gcctatgcca tacacaagcc atttcccttc 200

 tttgaaggcc tcctagacaa ctccatcatc actaagagaa tgtacatgga 250

 atctctggaa gcctgtagaa atttgatccc tgtatccaga gtggtgcaca 300

 acattctcac ccaactggag aggactttta acctgtctct tctggtgaca 350

 ttgttcagtc aaattaacct gcgtgaatat cccaatctgg tgacgattta 400

 cagaagcttc aaacgtgttg gtgcttccta tgaacggcag agcagagaca 450

 caccaatcct acttgaagcc ccaactggcc tagcagaagg aagctccctc 500

 cataccccac tggcgctgcc cccaccacaa ccccctcaac caagctgttc 550

 accctgtgcg ccaagagtca gtgagcctgg aacatcctcc cagcaaagcg 600

 atgagatcct gagtgagtcg cccagcccat ctgaccctgt cctgcctctc 650

 cctgcactca tccaggaagg aagaagcact tcagtgacca atgacaagtt 700

 aacatccaaa atgaatgcgg aagaagactc agaagagatg cccagcctcc 750

 tcactagcac tgtgcaagtg gccagtgaca acctgatccc ccaaataaga 800

 gataaagaag accctcaaga gatgccccac tctcccttgg gctctatgcc 850

 agagataaga gataattctc cagaaccaaa tgacccagaa gagccccagg 900

 aggtgtccag cacaccttca gacaagaaag gaaagaaaag aaaaagatgt 950

 atctggtcaa ctccaaaaag gagacataag aaaaaaagcc tcccaagagg 1000

 gacagcctca tctagacacg gaatccaaaa gaagctcaaa agggtggatc 1050

 aggttcctca aaagaaagat gactcaactt gtaactccac ggtagagaca 1100

 agggcccaaa aggcgagaac tgaatgtgcc cgaaagtcga gatcagagga 1150

 gatcattgat ggcacttcag aaatgaatga aggaaagagg tcccagaaga 1200

 cgcctagtac accacgaagg gtcacacaag gggcagcctc acctgggcat 1250

 ggcatccaag agaagctcca agtggtggat aaggtgactc aaaggaaaga 1300

 cgactcaacc tggaactcag aggtcatgat gagggtccaa aaggcaagaa 1350

 ctaaatgtgc ccgaaagtcc agatcgaaag aaaagaaaaa ggagaaagat 1400

 atctgttcaa gctcaaaaag gagatttcag aaaaatattc accgaagagg 1450

 aaaacccaaa agtgacactg tggattttca ctgttctaag ctccccgtga 1500

 cctgtggtga ggcgaaaggg attttatata agaagaaaat gaaacacgga 1550

 tcctcagtga agtgcattcg gaatgaggat ggaacttggt taacaccaaa 1600

 tgaatttgaa gtcgaaggaa aaggaaggaa cgcaaagaac tggaaacgga 1650

 atatacgttg tgaaggaatg accctaggag agctgctgaa gcggaaaaac 1700

 tcggatgaat gcgaggtgtg ctgtcaaggg ggacaacttc tctgctgcgg 1750

 tacttgtcca cgagtcttcc atgaggactg tcacatcccc cctgtggaag 1800

 ccaagaggat gctgtggagt tgcaccttct gcaggatgaa gaggtcttca 1850

 ggaagccaac agtgccatca tgtatctaag accctggaga ggcagatgca 1900

 gcctcaggac cagctgaaat gtgagttcct cctcttgaag gcctactgtc 1950

 atccacaaag ctcctttttt acgggcatcc catttaatat tcgagattac 2000

 ggtgagccct ttcaggaagc aatgtggttg gacctggtta aggaaaggct 2050

 gattacggaa atgtacacgg tggcatggtt tgtgcgagac atgcgcctga 2100

 tgtttcgcaa ccataaaaca ttttacaagg cttctgactt tggccaggta 2150

 ggacttgact tagaggcaga atttgaaaaa gatctcaaag acgtgctcgg 2200

 ttttcatgaa gccaatgacg gcggtttctg gactcttcct tgaccctgtt 2250

 ctgtaaagac tgaagcatcc ccacctcagg attcagctga tgggaccctg 2300

 gcttggactg ttgattgcca gtgagtctgg gatgtaattg gctgccctca 2350

 ggacccaaac ccagacactt cataggatta tcacaccctc catctttatt 2400

 ctttcttttt acctttaaaa gtctatatct a 2431

<210> 2085
<211> 713
<212> PRT
<213> Homo sapien

<400> 2085
 Met Phe Thr Met Thr Arg Ala Met Glu Glu Ala Leu Phe Gln His
   1               5                  10                  15

 Phe Met His Gln Lys Leu Gly Ile Ala Tyr Ala Ile His Lys Pro
                  20                  25                  30

 Phe Pro Phe Phe Glu Gly Leu Leu Asp Asn Ser Ile Ile Thr Lys
                  35                  40                  45

 Arg Met Tyr Met Glu Ser Leu Glu Ala Cys Arg Asn Leu Ile Pro
                  50                  55                  60

 Val Ser Arg Val Val His Asn Ile Leu Thr Gln Leu Glu Arg Thr
                  65                  70                  75

 Phe Asn Leu Ser Leu Leu Val Thr Leu Phe Ser Gln Ile Asn Leu
                  80                  85                  90

 Arg Glu Tyr Pro Asn Leu Val Thr Ile Tyr Arg Ser Phe Lys Arg
                  95                 100                 105

 Val Gly Ala Ser Tyr Glu Arg Gln Ser Arg Asp Thr Pro Ile Leu
                 110                 115                 120

 Leu Glu Ala Pro Thr Gly Leu Ala Glu Gly Ser Ser Leu His Thr
                 125                 130                 135

 Pro Leu Ala Leu Pro Pro Pro Gln Pro Pro Gln Pro Ser Cys Ser
                 140                 145                 150

 Pro Cys Ala Pro Arg Val Ser Glu Pro Gly Thr Ser Ser Gln Gln
                 155                 160                 165

 Ser Asp Glu Ile Leu Ser Glu Ser Pro Ser Pro Ser Asp Pro Val
                 170                 175                 180

 Leu Pro Leu Pro Ala Leu Ile Gln Glu Gly Arg Ser Thr Ser Val
                 185                 190                 195

 Thr Asn Asp Lys Leu Thr Ser Lys Met Asn Ala Glu Glu Asp Ser
                 200                 205                 210

 Glu Glu Met Pro Ser Leu Leu Thr Ser Thr Val Gln Val Ala Ser
                 215                 220                 225

 Asp Asn Leu Ile Pro Gln Ile Arg Asp Lys Glu Asp Pro Gln Glu
                 230                 235                 240

 Met Pro His Ser Pro Leu Gly Ser Met Pro Glu Ile Arg Asp Asn
                 245                 250                 255

 Ser Pro Glu Pro Asn Asp Pro Glu Glu Pro Gln Glu Val Ser Ser
                 260                 265                 270

 Thr Pro Ser Asp Lys Lys Gly Lys Lys Arg Lys Arg Cys Ile Trp
                 275                 280                 285

 Ser Thr Pro Lys Arg Arg His Lys Lys Lys Ser Leu Pro Arg Gly
                 290                 295                 300

 Thr Ala Ser Ser Arg His Gly Ile Gln Lys Lys Leu Lys Arg Val
                 305                 310                 315

 Asp Gln Val Pro Gln Lys Lys Asp Asp Ser Thr Cys Asn Ser Thr
                 320                 325                 330

 Val Glu Thr Arg Ala Gln Lys Ala Arg Thr Glu Cys Ala Arg Lys
                 335                 340                 345

 Ser Arg Ser Glu Glu Ile Ile Asp Gly Thr Ser Glu Met Asn Glu
                 350                 355                 360

 Gly Lys Arg Ser Gln Lys Thr Pro Ser Thr Pro Arg Arg Val Thr
                 365                 370                 375

 Gln Gly Ala Ala Ser Pro Gly His Gly Ile Gln Glu Lys Leu Gln
                 380                 385                 390

 Val Val Asp Lys Val Thr Gln Arg Lys Asp Asp Ser Thr Trp Asn
                 395                 400                 405

 Ser Glu Val Met Met Arg Val Gln Lys Ala Arg Thr Lys Cys Ala
                 410                 415                 420

 Arg Lys Ser Arg Ser Lys Glu Lys Lys Lys Glu Lys Asp Ile Cys
                 425                 430                 435

 Ser Ser Ser Lys Arg Arg Phe Gln Lys Asn Ile His Arg Arg Gly
                 440                 445                 450

 Lys Pro Lys Ser Asp Thr Val Asp Phe His Cys Ser Lys Leu Pro
                 455                 460                 465

 Val Thr Cys Gly Glu Ala Lys Gly Ile Leu Tyr Lys Lys Lys Met
                 470                 475                 480

 Lys His Gly Ser Ser Val Lys Cys Ile Arg Asn Glu Asp Gly Thr
                 485                 490                 495

 Trp Leu Thr Pro Asn Glu Phe Glu Val Glu Gly Lys Gly Arg Asn
                 500                 505                 510

 Ala Lys Asn Trp Lys Arg Asn Ile Arg Cys Glu Gly Met Thr Leu
                 515                 520                 525

 Gly Glu Leu Leu Lys Arg Lys Asn Ser Asp Glu Cys Glu Val Cys
                 530                 535                 540

 Cys Gln Gly Gly Gln Leu Leu Cys Cys Gly Thr Cys Pro Arg Val
                 545                 550                 555

 Phe His Glu Asp Cys His Ile Pro Pro Val Glu Ala Lys Arg Met
                 560                 565                 570

 Leu Trp Ser Cys Thr Phe Cys Arg Met Lys Arg Ser Ser Gly Ser
                 575                 580                 585

 Gln Gln Cys His His Val Ser Lys Thr Leu Glu Arg Gln Met Gln
                 590                 595                 600

 Pro Gln Asp Gln Leu Lys Cys Glu Phe Leu Leu Leu Lys Ala Tyr
                 605                 610                 615

 Cys His Pro Gln Ser Ser Phe Phe Thr Gly Ile Pro Phe Asn Ile
                 620                 625                 630

 Arg Asp Tyr Gly Glu Pro Phe Gln Glu Ala Met Trp Leu Asp Leu
                 635                 640                 645

 Val Lys Glu Arg Leu Ile Thr Glu Met Tyr Thr Val Ala Trp Phe
                 650                 655                 660

 Val Arg Asp Met Arg Leu Met Phe Arg Asn His Lys Thr Phe Tyr
                 665                 670                 675

 Lys Ala Ser Asp Phe Gly Gln Val Gly Leu Asp Leu Glu Ala Glu
                 680                 685                 690

 Phe Glu Lys Asp Leu Lys Asp Val Leu Gly Phe His Glu Ala Asn
                 695                 700                 705

 Asp Gly Gly Phe Trp Thr Leu Pro
                 710

<210> 2086
<211> 6475
<212> DNA
<213> Homo sapien

<400> 2086
 gccgggcagt gggcaggtat ggctgagggc gtgtgagcgc cgagcgctaa 50

 gggccgccgc caccatgcca gggggcgcag gcgccgccag gctctgcttg 100

 ctggcgtttg ccctgcagcc cctccggccg cgggcggcgc gggagcctgg 150

 atggacaaga ggaagtgagg aaggcagccc caagctgcag catgaactta 200

 tcatacctca gtggaagact tcagaaagcc ccgtgagaga aaagcatcca 250

 ctcaaagctg agctcagggt aatggctgag gggcgagaac tgatcctgga 300

 cctggagaag aatgagcaac tttttgctcc ttcctacaca gaaacccatt 350

 atacttcaag tggtaaccct caaaccacca cacggaaatt ggaggatcac 400

 tgcttttacc acggcacggt gagggagaca gaactgtcca gcgtcacgct 450

 cagcacttgc cgaggaatta gaggactgat tacggtgagc agcaacctca 500

 gctacgtcat cgagcccctc cctgacagca agggccaaca ccttatttac 550

 agatctgaac atctcaagcc gcccccggga aactgtgggt tcgagcactc 600

 caagcccacc accagggact gggctcttca gtttacacaa cagaccaaga 650

 agcgacctcg caggatgaaa agggaagatt taaactccat gaagtatgtg 700

 gagctttacc tcgtggctga ttatttagag tttcagaaga atcgacgaga 750

 ccaggacgcc accaaacaca agctcataga gatcgccaac tatgttgata 800

 agttttaccg atccttgaac atccggattg ctctcgtggg cttggaagtg 850

 tggacccacg ggaacatgtg tgaagtttca gagaatccat attctaccct 900

 ctggtccttt ctcagttgga ggcgcaagct gcttgcccag aagtaccatg 950

 acaacgccca attaatcacg ggcatgtcct tccacggcac caccatcggc 1000

 ctggcccccc tcatggccat gtgctctgtg taccagtctg gaggagtcaa 1050

 catggaccac tccgagaatg ccattggcgt ggctgccacc atggcccacg 1100

 agatgggcca caactttggc atgacccatg attctgcaga ttgctgctcg 1150

 gccagtgcgg ctgatggtgg gtgcatcatg gcagctgcca ctgggcaccc 1200

 ctttcccaaa gtgttcaatg gatgcaacag gagggagctg gacaggtatc 1250

 tgcagtcagg tggtggaatg tgtctctcca acatgccaga caccaggatg 1300

 ttgtatggag gccggaggtg tgggaacggg tatctggaag atggggaaga 1350

 gtgtgactgt ggagaagaag aggaatgtaa caacccctgc tgcaatgcct 1400

 ctaattgtac cctgaggccg ggggcggagt gtgctcacgg ctcctgctgc 1450

 caccagtgta agctgttggc tcctgggacc ctgtgccgcg agcaggccag 1500

 gcagtgtgac ctcccggagt tctgtacggg caagtctccc cactgcccta 1550

 ccaacttcta ccagatggat ggtaccccct gtgagggcgg ccaggcctac 1600

 tgctacaacg gcatgtgcct cacctaccag gagcagtgcc agcagctgtg 1650

 gggacccgga gcccgacctg cccctgacct ctgcttcgag aaggtgaatg 1700

 tggcaggaga cacctttgga aactgtggaa aggacatgaa tggtgaacac 1750

 aggaagtgca acatgagaga tgcgaagtgt gggaagatcc agtgtcagag 1800

 ctctgaggcc cggcccctgg agtccaacgc ggtgcccatt gacaccacta 1850

 tcatcatgaa tgggaggcag atccagtgcc ggggcaccca cgtctaccga 1900

 ggtcctgagg aggagggtga catgctggac ccagggctgg tgatgactgg 1950

 aaccaagtgt ggctacaacc atatttgctt tgaggggcag tgcaggaaca 2000

 cctccttctt tgaaactgaa ggctgtggga agaagtgcaa tggccatggg 2050

 gtctgtaaca acaaccagaa ctgccactgc ctgccgggct gggccccgcc 2100

 cttctgcaac acaccgggcc acgggggcag tatcgacagt gggcctatgc 2150

 cccctgagag tgtgggtcct gtggtagctg gagtgttggt ggccatcttg 2200

 gtgctggcgg tcctcatgct gatgtactac tgctgcagac agaacaacaa 2250

 actaggccaa ctcaagccct cagctctccc ttccaagctg aggcaacagt 2300

 tcagttgtcc cttcagggtt tctcagaaca gcgggactgg tcatgccaac 2350

 ccaactttca agctgcagac gccccagggc aagcgaaagg tgatcaacac 2400

 tccggaaatc ctgcggaagc cctcccagcc tcctccccgg ccccctccag 2450

 attatctgcg tggtgggtcc ccacctgcac cactgccagc tcacctgagc 2500

 agggctgcta ggaactcccc agggcccggg tctcaaatag agaggacgga 2550

 gtcgtccagg aggcctcctc caagccggcc aattcccccc gcaccaaatt 2600

 gcatcgtttc ccaggacttc tccaggcctc ggccgcccca gaaggcactc 2650

 ccggcaaacc cagtgccagg ccgcaggagc ctccccaggc caggaggtgc 2700

 atccccactg cggccccctg gtgctggccc tcagcagtcc cggcctctgg 2750

 cagcacttgc cccaaagttt ccagaataca gatcacagag ggctggaggg 2800

 atgattagct cgaaaatcta gacctgtcca aggggcttct ccctttcctt 2850

 gagctctctg gacactgcag aggacccatg accatggaac cctgaagaag 2900

 catgtctggc cgcctctgag ctcctcccac cctcctccag gaacctccac 2950

 atctccaaaa atctccctgt tgactcagtg cctcctcggc ttccttggaa 3000

 gcccagaggg actatgatct gatggcctct aggtgttgtt ttgtgcaata 3050

 tacagcccca ggtagggagg ggagagtatg aggagggtga ctggcagctt 3100

 ctcctccaga ctcctagccc cgaggtgctg atggagatgc tcaaggccag 3150

 caagcccctc aggccagcac ttcgcttgca gaagccatcc attcactcct 3200

 ggggtgcagg gcacgcaaga gagcttccca ttgcttctgc tctcctcaga 3250

 ggtcccgggc tggatggagg tggtacttac ccaccccttt tagcttttag 3300

 ggattaagga agggtcaagc cagccactgc tgtggccctg cccagggctt 3350

 ggttgaggga acggcttctg gctgtatggc tgcatgtgac aagccacgtc 3400

 ccctcccacc tctccccaaa cccctgcatc cctgtattca cacgggtcac 3450

 tctgactcag acaggtacta ttcgtaggca gtgtagacag caggaggagc 3500

 accgggcttg ggcttcctct gagccgtgat gccaaaggtt gcgactcctg 3550

 actctggata atttttagtt gctctttgtt ttctctgccg cactttcctg 3600

 gtgccccacg cttttctctc ttccttcccc tctcattctc cctctaatgt 3650

 gtggtgcttt ggtgagcaaa ccctcagcag tcctgacctt cgggtgacca 3700

 ggtgcttgtg acctacaagt cagagtccac tctcacagtc ggccactgga 3750

 tttccctcac tggctctcag gagtgtgacc agagtagact cggggcatgg 3800

 ccattggggt catatgttta tttttcattg tgttttgtga cctcagcagg 3850

 gtgggggtct tcctccttac tctaagctaa atctaggtga ggtttcccct 3900

 tagggagccc agctatttac aaagtacaca cgagggagca ggctggtcat 3950

 tgacttcggg ctggaccgtt gccctctgag cagagaacag acccattttc 4000

 tgggagctgc ccgagatcac tggagaaggc agccagcagc agctgcactg 4050

 gaacagtcag agcagggagc ctcttcctca acccagcttt ttgtcattca 4100

 cttccttttg ttctctctct ggtcactgcc cttacctgac cctcacagaa 4150

 agagagctct gagcaggtga gggggtctgc ggtggctcct gtcttccctg 4200

 cagcagggaa ggagggccgt gtggtgcttt gctagatagg acggtttttg 4250

 caaagcacct ggagatgttt gctgggagat agactcccac tccacaaagg 4300

 tgctgggtgg ctctccggac aggagctggc ctgactctca ctcctctgag 4350

 gctttcctgg ggcctcctcc catcctgcca tgagcaattg tttgctcttg 4400

 aaaacctcac tgcaaggctg aagctgactt ctgattcacc accccagggc 4450

 ctccttatag ttctctgcac acaataggtg cttcttggat gttcttgggt 4500

 ttggaaataa gtggaaaata cgggatgtac ccctggggga aaagcctggg 4550

 ttgggtttag aaagatctca ggaaaatgag tttctcttcc ctcagggtgg 4600

 ctgtgataca ggttccccat gtccttgccg tgggtcatcc ttgctgtggg 4650

 tcatccttgc tgtggagatc cattccccac ctttcctgtg gcccaacctt 4700

 ttatttaaat gtgctaccct ctgcctcaag gcttggttcc tggaaagtaa 4750

 aggtgaaaac atcccctttc acccctctgc aaaacaaaca agcaacatcc 4800

 tcaaaaccca accccatgcc tcacagagct tcctgtggct tctccagcct 4850

 ttctccctca catcaggagg tagatagctc tgaaatgaca gcgccacagc 4900

 catagtgact gcatgagcca tctgaacctg cagtccaccc tccctggaac 4950

 cacaccagaa agagacctgg gttgtcgttt tcttgctttt tgttttgttt 5000

 tgttttatta ttttcatatc acctccatcc cataaagttg tactgtgaac 5050

 tggaagatgg tggaatgttt tggaatttga tagactttcg gcaaccagtt 5100

 ctactaatgc ttcactcctg gctctgttca gggaagctgc ccaggaagaa 5150

 gactggccat tatgcatccc cttttctttc cagtgcccag tatgctgttt 5200

 ttgaggtgtc aaatacaaat aaatctgggc ttagggaagg agagacctta 5250

 ttccaaagca tgattgcaga aggggaaagg gaatattgca aaagggagag 5300

 gaaggggcct tatgggaata gtgaaaaggc tcagaccgac cgatggcaag 5350

 atctgcaagc gtctcaaagc ccaggcagaa aaggactttt cttttattgg 5400

 aagaagtaaa catggctaga aagaaccacg ttcagggaat gacgttgtgc 5450

 ccagggtttt tttttttttt tttttttgtc tccaggggag gggctgtttg 5500

 ctggctcagg ctgaggatgg cccaaagtcc agggtctggt ggggaggagg 5550

 gaagcttaac tcaagtttgg gttagtgagt tagcaagctc tttgtgcaga 5600

 tggggatgta ggtaaatctt tttaaaagtg aaattaacct cctgccaatt 5650

 ttacaaccca agaatttttt tttaagggcc ttggagccat ctctaaaaca 5700

 aacctcaagg gatttagtgc cctgtctccc tgtctctaga agccttagcc 5750

 tgggcacctg gctcaatctt gtaactgcct gctagccata gattcctttc 5800

 agccttgctg acttctccct ataagagtaa agcctttttc tgccccagct 5850

 ctgagacact tgcagatctt aaggtctgag acttgctgat tttctggttg 5900

 gagtgttttt ttgtattgcc atagtccctt ccccctgaag caatagcccc 5950

 tccccacctc ctgcaatacg cctttccaat ctttattgga agtctctccc 6000

 tgcctacttc ctaatttatt cttatttgac agagggtatg gaagacttgc 6050

 aatttgaaaa ctggggacca gttccaaagt cagtaattgt gttaaccacg 6100

 tgtataacag ctctgctgga cacccaagaa agccatggga acaccaactg 6150

 gaaaggtccc cttccccagg ggagcctgcg aaggagaggt tctgtagaat 6200

 ccaagcccac atttccaaag tcacccccaa cgcgtcctct cacaccgtcc 6250

 actgtgcgtt tgtatgtgtc tgggatccag ggcaatgtga attttctttt 6300

 tatttgggag attgttcacg gaaaacagat cttcttctct cttgtccacc 6350

 tattaattgt ttacaatatt tgtacatcta tgcaaaatac ttgaatgggc 6400

 catggtgcct tttttccttg ttagtattta attaaaaatg aattgtttgt 6450

 catttgcaat gttaaaaaaa aaaaa 6475

<210> 2087
<211> 918
<212> PRT
<213> Homo sapien

<400> 2087
 Met Pro Gly Gly Ala Gly Ala Ala Arg Leu Cys Leu Leu Ala Phe
   1               5                  10                  15

 Ala Leu Gln Pro Leu Arg Pro Arg Ala Ala Arg Glu Pro Gly Trp
                  20                  25                  30

 Thr Arg Gly Ser Glu Glu Gly Ser Pro Lys Leu Gln His Glu Leu
                  35                  40                  45

 Ile Ile Pro Gln Trp Lys Thr Ser Glu Ser Pro Val Arg Glu Lys
                  50                  55                  60

 His Pro Leu Lys Ala Glu Leu Arg Val Met Ala Glu Gly Arg Glu
                  65                  70                  75

 Leu Ile Leu Asp Leu Glu Lys Asn Glu Gln Leu Phe Ala Pro Ser
                  80                  85                  90

 Tyr Thr Glu Thr His Tyr Thr Ser Ser Gly Asn Pro Gln Thr Thr
                  95                 100                 105

 Thr Arg Lys Leu Glu Asp His Cys Phe Tyr His Gly Thr Val Arg
                 110                 115                 120

 Glu Thr Glu Leu Ser Ser Val Thr Leu Ser Thr Cys Arg Gly Ile
                 125                 130                 135

 Arg Gly Leu Ile Thr Val Ser Ser Asn Leu Ser Tyr Val Ile Glu
                 140                 145                 150

 Pro Leu Pro Asp Ser Lys Gly Gln His Leu Ile Tyr Arg Ser Glu
                 155                 160                 165

 His Leu Lys Pro Pro Pro Gly Asn Cys Gly Phe Glu His Ser Lys
                 170                 175                 180

 Pro Thr Thr Arg Asp Trp Ala Leu Gln Phe Thr Gln Gln Thr Lys
                 185                 190                 195

 Lys Arg Pro Arg Arg Met Lys Arg Glu Asp Leu Asn Ser Met Lys
                 200                 205                 210

 Tyr Val Glu Leu Tyr Leu Val Ala Asp Tyr Leu Glu Phe Gln Lys
                 215                 220                 225

 Asn Arg Arg Asp Gln Asp Ala Thr Lys His Lys Leu Ile Glu Ile
                 230                 235                 240

 Ala Asn Tyr Val Asp Lys Phe Tyr Arg Ser Leu Asn Ile Arg Ile
                 245                 250                 255

 Ala Leu Val Gly Leu Glu Val Trp Thr His Gly Asn Met Cys Glu
                 260                 265                 270

 Val Ser Glu Asn Pro Tyr Ser Thr Leu Trp Ser Phe Leu Ser Trp
                 275                 280                 285

 Arg Arg Lys Leu Leu Ala Gln Lys Tyr His Asp Asn Ala Gln Leu
                 290                 295                 300

 Ile Thr Gly Met Ser Phe His Gly Thr Thr Ile Gly Leu Ala Pro
                 305                 310                 315

 Leu Met Ala Met Cys Ser Val Tyr Gln Ser Gly Gly Val Asn Met
                 320                 325                 330

 Asp His Ser Glu Asn Ala Ile Gly Val Ala Ala Thr Met Ala His
                 335                 340                 345

 Glu Met Gly His Asn Phe Gly Met Thr His Asp Ser Ala Asp Cys
                 350                 355                 360

 Cys Ser Ala Ser Ala Ala Asp Gly Gly Cys Ile Met Ala Ala Ala
                 365                 370                 375

 Thr Gly His Pro Phe Pro Lys Val Phe Asn Gly Cys Asn Arg Arg
                 380                 385                 390

 Glu Leu Asp Arg Tyr Leu Gln Ser Gly Gly Gly Met Cys Leu Ser
                 395                 400                 405

 Asn Met Pro Asp Thr Arg Met Leu Tyr Gly Gly Arg Arg Cys Gly
                 410                 415                 420

 Asn Gly Tyr Leu Glu Asp Gly Glu Glu Cys Asp Cys Gly Glu Glu
                 425                 430                 435

 Glu Glu Cys Asn Asn Pro Cys Cys Asn Ala Ser Asn Cys Thr Leu
                 440                 445                 450

 Arg Pro Gly Ala Glu Cys Ala His Gly Ser Cys Cys His Gln Cys
                 455                 460                 465

 Lys Leu Leu Ala Pro Gly Thr Leu Cys Arg Glu Gln Ala Arg Gln
                 470                 475                 480

 Cys Asp Leu Pro Glu Phe Cys Thr Gly Lys Ser Pro His Cys Pro
                 485                 490                 495

 Thr Asn Phe Tyr Gln Met Asp Gly Thr Pro Cys Glu Gly Gly Gln
                 500                 505                 510

 Ala Tyr Cys Tyr Asn Gly Met Cys Leu Thr Tyr Gln Glu Gln Cys
                 515                 520                 525

 Gln Gln Leu Trp Gly Pro Gly Ala Arg Pro Ala Pro Asp Leu Cys
                 530                 535                 540

 Phe Glu Lys Val Asn Val Ala Gly Asp Thr Phe Gly Asn Cys Gly
                 545                 550                 555

 Lys Asp Met Asn Gly Glu His Arg Lys Cys Asn Met Arg Asp Ala
                 560                 565                 570

 Lys Cys Gly Lys Ile Gln Cys Gln Ser Ser Glu Ala Arg Pro Leu
                 575                 580                 585

 Glu Ser Asn Ala Val Pro Ile Asp Thr Thr Ile Ile Met Asn Gly
                 590                 595                 600

 Arg Gln Ile Gln Cys Arg Gly Thr His Val Tyr Arg Gly Pro Glu
                 605                 610                 615

 Glu Glu Gly Asp Met Leu Asp Pro Gly Leu Val Met Thr Gly Thr
                 620                 625                 630

 Lys Cys Gly Tyr Asn His Ile Cys Phe Glu Gly Gln Cys Arg Asn
                 635                 640                 645

 Thr Ser Phe Phe Glu Thr Glu Gly Cys Gly Lys Lys Cys Asn Gly
                 650                 655                 660

 His Gly Val Cys Asn Asn Asn Gln Asn Cys His Cys Leu Pro Gly
                 665                 670                 675

 Trp Ala Pro Pro Phe Cys Asn Thr Pro Gly His Gly Gly Ser Ile
                 680                 685                 690

 Asp Ser Gly Pro Met Pro Pro Glu Ser Val Gly Pro Val Val Ala
                 695                 700                 705

 Gly Val Leu Val Ala Ile Leu Val Leu Ala Val Leu Met Leu Met
                 710                 715                 720

 Tyr Tyr Cys Cys Arg Gln Asn Asn Lys Leu Gly Gln Leu Lys Pro
                 725                 730                 735

 Ser Ala Leu Pro Ser Lys Leu Arg Gln Gln Phe Ser Cys Pro Phe
                 740                 745                 750

 Arg Val Ser Gln Asn Ser Gly Thr Gly His Ala Asn Pro Thr Phe
                 755                 760                 765

 Lys Leu Gln Thr Pro Gln Gly Lys Arg Lys Val Ile Asn Thr Pro
                 770                 775                 780

 Glu Ile Leu Arg Lys Pro Ser Gln Pro Pro Pro Arg Pro Pro Pro
                 785                 790                 795

 Asp Tyr Leu Arg Gly Gly Ser Pro Pro Ala Pro Leu Pro Ala His
                 800                 805                 810

 Leu Ser Arg Ala Ala Arg Asn Ser Pro Gly Pro Gly Ser Gln Ile
                 815                 820                 825

 Glu Arg Thr Glu Ser Ser Arg Arg Pro Pro Pro Ser Arg Pro Ile
                 830                 835                 840

 Pro Pro Ala Pro Asn Cys Ile Val Ser Gln Asp Phe Ser Arg Pro
                 845                 850                 855

 Arg Pro Pro Gln Lys Ala Leu Pro Ala Asn Pro Val Pro Gly Arg
                 860                 865                 870

 Arg Ser Leu Pro Arg Pro Gly Gly Ala Ser Pro Leu Arg Pro Pro
                 875                 880                 885

 Gly Ala Gly Pro Gln Gln Ser Arg Pro Leu Ala Ala Leu Ala Pro
                 890                 895                 900

 Lys Phe Pro Glu Tyr Arg Ser Gln Arg Ala Gly Gly Met Ile Ser
                 905                 910                 915

 Ser Lys Ile


<210> 2088
<211> 3452
<212> DNA
<213> Homo sapien

<400> 2088
 ctgaagcttg catgcctgca ggtcgaccca cgcgtccgcg gacgcgtggg 50

 cggacgcgtg ggtttttcct ttcttccaga aggagattta accatagtag 100

 aaagaatgga gaactattaa ctgccttcct tctgtgggct gtgattttca 150

 gaggggaatg ctaagaggtg attttcaatg ttgggactca aaggtgaaga 200

 cactgaagga cagaattttt ggcagaggaa agatcttctt cggtcaccat 250

 acttgagtta gctctaggga agtggaggtt tccatttgga attctatagc 300

 ttcttccagg tcatagtgtc tgccccccac cttccagtat ctcctgatat 350

 gcagcatgaa tgaaaatggc aagtttcctg gccttccttc tgctcaactt 400

 tcgtgtctgc ctccttttgc ttcagctgct catgcctcac tcagctcagt 450

 tttctgtgct tggaccctct gggcccatcc tggccatggt gggtgaagac 500

 gctgatctgc cctgtcacct gttcccgacc atgagtgcag agaccatgga 550

 gctgaagtgg gtgagttcca gcctaaggca ggtggtgaac gtgtatgcag 600

 atggaaagga agtggaagac aggcagagtg caccgtatcg agggagaact 650

 tcgattctgc gggatggcat cactgcaggg aaggctgctc tccgaataca 700

 caacgtcaca gcctctgaca gtggaaagta cttgtgttat ttccaagatg 750

 gtgacttcta tgaaaaagcc ctggtggagc tgaaggttgc agcactgggt 800

 tctgatcttc acgttgatgt gaagggttac aaggatggag ggatccatct 850

 ggagtgcagg tccactggct ggtaccccca accccaaata cagtggagca 900

 acaacaaggg agagaacatc ccgactgtgg aagcacctgt ggttgcagac 950

 ggagtgggcc tgtatgcagt agcagcatct gtgatcatga gaggcagctc 1000

 tggggagggt gtatcctgta ccatcagaag ttccctcctc ggcctggaaa 1050

 agacagccag catttccatc gcagacccct tcttcaggag cgcccagagg 1100

 tggatcgccg ccctggcacg gaccctgcct gtcttgctgc tgcttcttgg 1150

 gggagccggt tacttcctgt ggcaacagca ggaggaaaaa aagactcagt 1200

 tcagaaagaa aaagagagag caagagttga gagaaatggc atggagcaca 1250

 atgaagcaag aacaaagcac aagagtgaag ctcctggagg aactcagatg 1300

 gagaagtatc cagtatgcat ctcggggaga gagacattca gcctataatg 1350

 aatggaaaaa ggccctcttc aagcctgcgg atgtgattct ggatccaaaa 1400

 acagcaaacc ccatcctcct tgtttctgag gaccagagga gtgtgcagcg 1450

 tgccaaggag ccccaggatc tgccagacaa ccctgagaga tttaattggc 1500

 attattgtgt tctcggctgt gagagcttca tatcagggag acattactgg 1550

 gaggtggagg taggggacag gaaagagtgg catatagggg tgtgcagtaa 1600

 gaatgtgcag agaaaaggct gggtcaaaat gacacctgag aatggattct 1650

 ggactatggg gctgactgat gggaataagt atcggactct aactgagccc 1700

 agaaccaacc tgaaacttcc taagccccct aagaaagtgg gggtcttcct 1750

 ggactatgag actggagata tctcattcta caatgctgtg gatggatcgc 1800

 atattcatac tttcctggac gtctccttct ctgaggctct atatcctgtt 1850

 ttcagaattt tgaccttgga gcccacggcc ctgagtattt gtccagcgtg 1900

 aaaagaagaa gagagttcct ccaattctga ccgagtgctg atcattccct 1950

 agagacacca gtaaccccgg gcttagctaa cgaaagtggg gagcctcagg 2000

 ctgaagtaac ttttctctgc ttctccctgc ccagctcaga gctgagggcc 2050

 tccccctcca cagcaaccaa tcacaaccat aaagctacaa gcacgcactg 2100

 aagcacttta ctgatactca ttcaattatt catatgacag ttgtttgagt 2150

 ttggtaccat cttattttcc ccttatacag ataaggaaac tggggtgcag 2200

 aaaagtgaat tgactacaaa gtagacatga ctagttaaca acacagctgg 2250

 gatctaaaca gcaataacta acattaatgg agaacttaaa atgctctgag 2300

 tgctgtgtta tgagctttgg tggatgtcac tcctttaatc ctcgcaacac 2350

 cctgtcgggt agtctcattt agcaagtatg gaagttgagg cagggcaaca 2400

 ttaagcaact tacataactc atgcagtaat ttctgcagtt gggagatgtt 2450

 cagcttcagt ccccggccct atggccgttc ttttccaccc tgtttcttcc 2500

 cccataggaa gaacccacct gtagccctga ggttcttttc ccaggatggc 2550

 tccaggataa ggatcactgt aggtggttgt ggagttgaca cccctgttga 2600

 ctccttccca gctgattgtc agagccttag acccagcacg ccttggatta 2650

 gctttgcaga gtgtcttggt tgagagaata acctcaccgt acccacatga 2700

 cacgtgattt ggaaagagac tagaggccac acttgataaa tcatggggaa 2750

 cagatgtgtt ccacccaaca aatgtgataa gtgatcatgc agccagagcc 2800

 agccttcctt caatcaaggt ttccaggcag agcaaatacc ctagagattt 2850

 tctgtgatat aggaaatttg gatgaaggga gctagaagaa atacagggat 2900

 tttttttttt ttttaagatg gagtcttact ctgttgctag gctggagtgc 2950

 agtggtgcga tctcagctcc ctgcaacctc cacctcctgg gttcaaacaa 3000

 ttctcctgcc tcagcctccc gagtactggg aatataggtg cacgccacca 3050

 cacccaacaa atttttgtac ttttagtaca gatgagggtt cactatgttg 3100

 gccaggatgg tctcgatctc ttgacctcat gatccaccca cctcggtctc 3150

 ccaaagtgct gggattacag gcttgagcca ccgggtgacc ggcttacagg 3200

 gatattttta atcccgttat ggactctgtc tccaggagag gggtctatcc 3250

 acccctgctc attggtggat gttaaaccaa tattcctttc aactgctgcc 3300

 tgctagggaa aaactactcc tcattatcat cattattatt gctctccact 3350

 gtatcccctc tacctggcat gtgcttgtca agttctagtt gttcaataaa 3400

 tttgttaata atgctgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3450

 aa 3452

<210> 2089
<211> 513
<212> PRT
<213> Homo sapien

<400> 2089
 Met Lys Met Ala Ser Phe Leu Ala Phe Leu Leu Leu Asn Phe Arg
   1               5                  10                  15

 Val Cys Leu Leu Leu Leu Gln Leu Leu Met Pro His Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Lys Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asp Leu
                 140                 145                 150

 His Val Asp Val Lys Gly Tyr Lys Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Gln Trp Ser
                 170                 175                 180

 Asn Asn Lys Gly Glu Asn Ile Pro Thr Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Ala Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Ser Ser Gly Glu Gly Val Ser Cys Thr Ile Arg Ser Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Arg Trp Ile Ala Ala Leu Ala Arg Thr
                 245                 250                 255

 Leu Pro Val Leu Leu Leu Leu Leu Gly Gly Ala Gly Tyr Phe Leu
                 260                 265                 270

 Trp Gln Gln Gln Glu Glu Lys Lys Thr Gln Phe Arg Lys Lys Lys
                 275                 280                 285

 Arg Glu Gln Glu Leu Arg Glu Met Ala Trp Ser Thr Met Lys Gln
                 290                 295                 300

 Glu Gln Ser Thr Arg Val Lys Leu Leu Glu Glu Leu Arg Trp Arg
                 305                 310                 315

 Ser Ile Gln Tyr Ala Ser Arg Gly Glu Arg His Ser Ala Tyr Asn
                 320                 325                 330

 Glu Trp Lys Lys Ala Leu Phe Lys Pro Ala Asp Val Ile Leu Asp
                 335                 340                 345

 Pro Lys Thr Ala Asn Pro Ile Leu Leu Val Ser Glu Asp Gln Arg
                 350                 355                 360

 Ser Val Gln Arg Ala Lys Glu Pro Gln Asp Leu Pro Asp Asn Pro
                 365                 370                 375

 Glu Arg Phe Asn Trp His Tyr Cys Val Leu Gly Cys Glu Ser Phe
                 380                 385                 390

 Ile Ser Gly Arg His Tyr Trp Glu Val Glu Val Gly Asp Arg Lys
                 395                 400                 405

 Glu Trp His Ile Gly Val Cys Ser Lys Asn Val Gln Arg Lys Gly
                 410                 415                 420

 Trp Val Lys Met Thr Pro Glu Asn Gly Phe Trp Thr Met Gly Leu
                 425                 430                 435

 Thr Asp Gly Asn Lys Tyr Arg Thr Leu Thr Glu Pro Arg Thr Asn
                 440                 445                 450

 Leu Lys Leu Pro Lys Pro Pro Lys Lys Val Gly Val Phe Leu Asp
                 455                 460                 465

 Tyr Glu Thr Gly Asp Ile Ser Phe Tyr Asn Ala Val Asp Gly Ser
                 470                 475                 480

 His Ile His Thr Phe Leu Asp Val Ser Phe Ser Glu Ala Leu Tyr
                 485                 490                 495

 Pro Val Phe Arg Ile Leu Thr Leu Glu Pro Thr Ala Leu Ser Ile
                 500                 505                 510

 Cys Pro Ala


<210> 2090
<211> 2500
<212> DNA
<213> Homo sapien

<400> 2090
 cccaggcgca gccaatggga agggtcggag gcatggcaca gccaatggga 50

 agggccgggg caccaaagcc aatgggaagg gccgggagcg cgcggcgcgg 100

 gagatttaaa ggctgctgga gtgaggggtc gcccgtgcac cctgtcccag 150

 ccgtcctgtc ctggctgctc gctctgcttc gctgcgcctc cactatgctc 200

 tccctccgtg tcccgctcgc gcccatcacg gacccgcagc agctgcagct 250

 ctcgccgctg aaggggctca gcttggtcga caaggagaac acgccgccgg 300

 ccctgagcgg gacccgcgtc ctggccagca agaccgcgag gaggatcttc 350

 caggagccca cggagccgaa aactaaagca gctgcccccg gcgtggagga 400

 tgagccgctg ctgagagaaa acccccgccg ctttgtcatc ttccccatcg 450

 agtaccatga tatctggcag atgtataaga aggcagaggc ttccttttgg 500

 accgccgagg aggttgacct ctccaaggac attcagcact gggaatccct 550

 gaaacccgag gagagatatt ttatatccca tgttctggct ttctttgcag 600

 caagcgatgg catagtaaat gaaaacttgg tggagcgatt tagccaagaa 650

 gttcagatta cagaagcccg ctgtttctat ggcttccaaa ttgccatgga 700

 aaacatacat tctgaaatgt atagtcttct tattgacact tacataaaag 750

 atcccaaaga aagggaattt ctcttcaatg ccattgaaac gatgccttgt 800

 gtcaagaaga aggcagactg ggccttgcgc tggattgggg acaaagaggc 850

 tacctatggt gaacgtgttg tagcctttgc tgcagtggaa ggcattttct 900

 tttccggttc ttttgcgtcg atattctggc tcaagaaacg aggactgatg 950

 cctggcctca cattttctaa tgaacttatt agcagagatg agggtttaca 1000

 ctgtgatttt gcttgcctga tgttcaaaca cctggtacac aaaccatcgg 1050

 aggagagagt aagagaaata attatcaatg ctgttcggat agaacaggag 1100

 ttcctcactg aggccttgcc tgtgaagctc attgggatga attgcactct 1150

 aatgaagcaa tacattgagt ttgtggcaga cagacttatg ctggaactgg 1200

 gttttagcaa ggttttcaga gtagagaacc catttgactt tatggagaat 1250

 atttcactgg aaggaaagac taacttcttt gagaagagag taggcgagta 1300

 tcagaggatg ggagtgatgt caagtccaac agagaattct tttaccttgg 1350

 atgctgactt ctaaatgaac tgaagatgtg cccttacttg gctgattttt 1400

 tttttccatc tcataagaaa aatcagctga agtgttacca actagccaca 1450

 ccatgaattg tccgtaatgt tcattaacag catctttaaa actgtgtagc 1500

 tacctcacaa ccagtcctgt ctgtttatag tgctggtagt atcacctttt 1550

 gccagaaggc ctggctggct gtgacttacc atagcagtga caatggcagt 1600

 cttggcttta aagtgagggg tgacccttta gtgagcttag cacagcggga 1650

 ttaaacagtc ctttaaccag cacagccagt taaaagatgc agcctcactg 1700

 cttcaacgca gattttaatg tttacttaaa tataaacctg gcactttaca 1750

 aacaaataaa cattgttttg tactcacggc ggcgataata gcttgattta 1800

 tttggtttct acaccaaata cattctcctg accactaatg ggagccaatt 1850

 cacaattcac taagtgacta aagtaagtta aacttgtgta gactaagcat 1900

 gtaattttta agttttattt taatgaatta aaatatttgt taaccaactt 1950

 taaagtcagt cctgtgtata cctagatatt agtcagttgg tgccagatag 2000

 aagacaggtt gtgtttttat cctgtggctt gtgtagtgtc ctgggattct 2050

 ctgccccctc tgagtagagt gttgtgggat aaaggaatct ctcagggcaa 2100

 ggagcttctt aagttaaatc actagaaatt taggggtgat ctgggccttc 2150

 atatgtgtga gaagccgttt cattttattt ctcactgtat tttcctcaac 2200

 gtctggttga tgagaaaaaa ttcttgaaga gttttcatat gtgggagcta 2250

 aggtagtatt gtaaaatttc aagtcatcct taaacaaaat gatccaccta 2300

 agatcttgcc cctgttaagt ggtgaaatca actagaggtg gttcctacaa 2350

 gttgttcatt ctagttttgt ttggtgtaag taggttgtgt gagttaattc 2400

 atttatattt actatgtctg ttaaatcaga aattttttat tatctatgtt 2450

 cttctagatt ttacctgtag ttcataaaaa aaaaaaaaaa aaaaaaaaaa 2500

<210> 2091
<211> 389
<212> PRT
<213> Homo sapien

<400> 2091
 Met Leu Ser Leu Arg Val Pro Leu Ala Pro Ile Thr Asp Pro Gln
   1               5                  10                  15

 Gln Leu Gln Leu Ser Pro Leu Lys Gly Leu Ser Leu Val Asp Lys
                  20                  25                  30

 Glu Asn Thr Pro Pro Ala Leu Ser Gly Thr Arg Val Leu Ala Ser
                  35                  40                  45

 Lys Thr Ala Arg Arg Ile Phe Gln Glu Pro Thr Glu Pro Lys Thr
                  50                  55                  60

 Lys Ala Ala Ala Pro Gly Val Glu Asp Glu Pro Leu Leu Arg Glu
                  65                  70                  75

 Asn Pro Arg Arg Phe Val Ile Phe Pro Ile Glu Tyr His Asp Ile
                  80                  85                  90

 Trp Gln Met Tyr Lys Lys Ala Glu Ala Ser Phe Trp Thr Ala Glu
                  95                 100                 105

 Glu Val Asp Leu Ser Lys Asp Ile Gln His Trp Glu Ser Leu Lys
                 110                 115                 120

 Pro Glu Glu Arg Tyr Phe Ile Ser His Val Leu Ala Phe Phe Ala
                 125                 130                 135

 Ala Ser Asp Gly Ile Val Asn Glu Asn Leu Val Glu Arg Phe Ser
                 140                 145                 150

 Gln Glu Val Gln Ile Thr Glu Ala Arg Cys Phe Tyr Gly Phe Gln
                 155                 160                 165

 Ile Ala Met Glu Asn Ile His Ser Glu Met Tyr Ser Leu Leu Ile
                 170                 175                 180

 Asp Thr Tyr Ile Lys Asp Pro Lys Glu Arg Glu Phe Leu Phe Asn
                 185                 190                 195

 Ala Ile Glu Thr Met Pro Cys Val Lys Lys Lys Ala Asp Trp Ala
                 200                 205                 210

 Leu Arg Trp Ile Gly Asp Lys Glu Ala Thr Tyr Gly Glu Arg Val
                 215                 220                 225

 Val Ala Phe Ala Ala Val Glu Gly Ile Phe Phe Ser Gly Ser Phe
                 230                 235                 240

 Ala Ser Ile Phe Trp Leu Lys Lys Arg Gly Leu Met Pro Gly Leu
                 245                 250                 255

 Thr Phe Ser Asn Glu Leu Ile Ser Arg Asp Glu Gly Leu His Cys
                 260                 265                 270

 Asp Phe Ala Cys Leu Met Phe Lys His Leu Val His Lys Pro Ser
                 275                 280                 285

 Glu Glu Arg Val Arg Glu Ile Ile Ile Asn Ala Val Arg Ile Glu
                 290                 295                 300

 Gln Glu Phe Leu Thr Glu Ala Leu Pro Val Lys Leu Ile Gly Met
                 305                 310                 315

 Asn Cys Thr Leu Met Lys Gln Tyr Ile Glu Phe Val Ala Asp Arg
                 320                 325                 330

 Leu Met Leu Glu Leu Gly Phe Ser Lys Val Phe Arg Val Glu Asn
                 335                 340                 345

 Pro Phe Asp Phe Met Glu Asn Ile Ser Leu Glu Gly Lys Thr Asn
                 350                 355                 360

 Phe Phe Glu Lys Arg Val Gly Glu Tyr Gln Arg Met Gly Val Met
                 365                 370                 375

 Ser Ser Pro Thr Glu Asn Ser Phe Thr Leu Asp Ala Asp Phe
                 380                 385

<210> 2092
<211> 4572
<212> DNA
<213> Homo sapien

<400> 2092
 ggcggcgcta gcttcggagt ctcccgcgcg cacctcagcc gcctcctagc 50

 ggcgcggcgc tcgctcctac gcctaaaatg accaatgtgt gatttcagtg 100

 gaataaatgg cgtccaaagt cacagatgct atagtctggt atcaaaagaa 150

 gattggagca tatgatcaac aaatatggga aaaatctgtt gaacagagag 200

 aaatcaaggg gctaaggaat aaaccaaaga aaacagcaca tgtgaaacca 250

 gacctcatag atgttgatct tgtaagaggg tctgcatttg caaaggcaaa 300

 gcctgaaagt ccttggactt ctctgaccag aaagggaatt gttcgagttg 350

 tatttttccc ctttttcttc cggtggtggt tacaagtaac atcaaaggtc 400

 atctttttct ggcttcttgt cctttatctt cttcaagttg ctgcaatagt 450

 attattctgc tccacttcta gcccacacag catacctctg acagaggtga 500

 ttgggccgat atggctgatg ctgctcctgg gaactgtgca ttgccagatt 550

 gtttccacaa gaacacccaa acctcctcta agtacagggg gtaaaagaag 600

 aaggaaatta agaaaagcag cccatttgga agtacatagg gaaggagatg 650

 gttctagtac cacagataac acacaagagg gagcagttca gaaccacggt 700

 acaagcacct ctcacagcgt tggcactgtc ttcagagatc tctggcatgc 750

 tgctttcttt ttatcaggat caaagaaagc aaagaattca attgataaat 800

 caactgaaac tgacaatggc tatgtatccc ttgatgggaa gaagactgtt 850

 aaaagcggtg aagatggaat acaaaaccat gaacctcagt gtgaaactat 900

 tcgaccagaa gagacagcct ggaacacagg aacactgagg aatggtccta 950

 gcaaagatac ccaaaggaca ataacaaatg tctctgatga agtctccagt 1000

 gaggaaggtc ctgaaacagg atactcatta cgtcgtcatg tggacaggac 1050

 ttctgaaggt gttcttcgga atagaaagtc acaccattat aagaaacatt 1100

 accctaatga ggacgcccct aaatcgggta ctagttgcag ctctcgctgt 1150

 tcaagttcca gacaggattc tgagagtgca aggccagaat ctgaaacaga 1200

 agatgtgtta tgggaagact tgttacattg tgcagaatgc cattcatctt 1250

 gtaccagtga gacagatgtg gaaaatcatc agattaatcc atgtgtgaaa 1300

 aaagaatata gagatgaccc ttttcatcag agtcatttgc cctggctcca 1350

 tagttcccac ccaggattag aaaaaataag tgctatagta tgggaaggta 1400

 atgattgtaa gaaagcagac atgtctgtac ttgaaatcag tggaatgata 1450

 atgaacagag tgaacagcca tataccagga ataggatacc agatttttgg 1500

 aaatgcagtc tctctcatac tgggtttaac tccatttgtt ttccgacttt 1550

 ctcaagctac agacttggaa caactcacag cacattctgc ttcagaactt 1600

 tatgtgattg catttggttc taatgaagat gtcatagttc tttctatggt 1650

 tataataagt tttgtggttc gcgtgtctct tgtgtggatt ttcttttttt 1700

 tgctctgtgt agcagaaaga acttataaac agcgattact ttttgcaaaa 1750

 ctctttggac atttaacatc tgcaaggagg gctcgaaaat ctgaggttcc 1800

 tcatttccgg ttgaagaaag tacagaatat aaaaatgtgg ctatctctcc 1850

 gttcctatct taagcgtcga ggtcctcagc gatcagttga tgtaatagtt 1900

 tcatctgctt tcttattgac tatctcagtt gtatttatct gttgtgccca 1950

 gataaacctc tacttgaaaa tggagaaaaa acctaacaaa aaggaggaac 2000

 tgacactagt gaataatgtt ttaaaactgg ctactaaact gctaaaggag 2050

 ttggacagtc cttttagatt atatgggctt acaatgaatc cgctgcttta 2100

 taacatcacc caggttgtta tcctgtcagc tgtttctggt gttatcagtg 2150

 acttgcttgg atttaattta aagctatgga agattaagtc atgacaattc 2200

 aaagaaaaga agatgtagcc tcttttccag aataagagta ctgactaagc 2250

 tgcctgaaag cttgtcactg attctttgct tcaggagtct cagctaggga 2300

 gttgaagtgt ttacatcaga ctgtcttgtg caattcttat atttatttta 2350

 ctggttcact tttttttaca tttattttag tctttatatt tttattttta 2400

 agcattgatg tacttagttg ttgaaagggt gatgaaactg atatccagat 2450

 acttgagatc ctggtaattg gtcataaata attggcaaaa taacaaattg 2500

 tgaaaataga agccattgct cagcaccgtt tctccatcaa tgccgtgaac 2550

 ttgccttact tgaggaaaaa ttctttaact ttggaatatt gcattgaact 2600

 cagctataca cataaaacat tttctttggt aaatcaagat ccagtcaggg 2650

 tttctcttga attattttgg aacaatgcca ggatccaaac tgattaagtt 2700

 acagtttaag cacccttcag tattaatata tacggtatta tataacaggt 2750

 caacaagtgc tctttgatga taaaacttgt aatagagcaa taattgtaaa 2800

 tggttaccat actgtaagat attttgataa aaattaacta gtaatacttg 2850

 tatttatttg aaacactggg ctgtttgcac agctccaact gtgcatgctc 2900

 aaaatgtgca ctttttaaaa ttgttacttt taatgcgtat ctttatatgg 2950

 gatctgttat agtatactag ggcatgatat ggtatccttt tgagtgaggt 3000

 atatactcat ctcacaagtg aagtgcctac tgatattact aaagtacatt 3050

 atgtttactc aagtaaataa ttttctcccc atggtacact ctagtgtagg 3100

 ctattcatac cacactgaaa tgaacaactg aagaataagg ctaagaacca 3150

 ataaaatatt tctctaattg ctagttgtaa aactgtatcc aaattttcag 3200

 aaaagacagc ttcagcttgc aaattctatc ctctaaactt atctggtgca 3250

 ttctccccac cccaccccca ttatataagg gctattttag atgcttttaa 3300

 cctccccaac aaataatttg ccaagtgtcc aatgagaact tatcatgttg 3350

 gtgtgttagg taaatcgggc aaatatgata gtgtcttaca ttgggccttg 3400

 attttaagtt gttatatttg tacaatcgag tattttagaa attacatgaa 3450

 acatgaaaca gtttttgcaa ttttttttaa actgggcatc tggtttctaa 3500

 aaatttattt gaaacaatct agaattttct tggtgcaaag tgtatcatgt 3550

 ggaatatcct catattttta ccatatttta agaactttaa gacgattaat 3600

 tgtaaataat ttatttgatt ggtgcagttc taatccctaa atcataatct 3650

 taaaatcagg aatgtgtgga gaacagagcc atgtcatatc actttgctct 3700

 taccattcct tttgatcagc ctcaattcag cctcattgtg tagtatgttt 3750

 tttctttcta tgaaaaacaa cagaaagcat ttcattttat ttgcctatgt 3800

 tcaaatatgt ttaataatga ccaaagtgca ttctgagttt tttcaaggaa 3850

 tgtaatactg gagctttaag aacatactta gtttctcatg tgaaaactta 3900

 ggctttgtct gatgtttttc cttcctctat tgtctaatgt tgaggttgtt 3950

 tttaggaatt atgttttata aactttttca atataaggta catgcctata 4000

 cagaacttaa cattttgcac agaatatatc aaatatattt tgagaaaaaa 4050

 agtacggcat gagttctgtt aggaataaaa gatgaaacta ttgtatctca 4100

 caaaaaatct tatttcagaa tggaaatatt tttgagaaaa gtagctgagt 4150

 atactggttt aagaaaatgc ttgttttaga ttgaggttaa cttagagttg 4200

 ggagttgatt tattaagtac agtatacctc tcaacagttt ataaataata 4250

 tgttgaatta tgtcagtgtg ggcagcagta gaatactaaa aggaaaatgt 4300

 catgttaagc aatttcagaa cattaactga actattttca aagcagaaaa 4350

 attgacattg ctgcctttaa gaataccatg aatgtaagaa attgaaagaa 4400

 attgtaaaat atcacataat atagaaatgg cagttcaaag agaattgtgg 4450

 cagatgttgt gtgtgaactg ttgtttcttt gccacatgtg ttgtatttga 4500

 aagttttaca gtaagtttaa aataaaacat tctgtgactg aaaaaaaaaa 4550

 aaaaaaaaaa aaaaaaaaaa aa 4572

<210> 2093
<211> 695
<212> PRT
<213> Homo sapien

<400> 2093
 Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys
   1               5                  10                  15

 Ile Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln
                  20                  25                  30

 Arg Glu Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His
                  35                  40                  45

 Val Lys Pro Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala
                  50                  55                  60

 Phe Ala Lys Ala Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg
                  65                  70                  75

 Lys Gly Ile Val Arg Val Val Phe Phe Pro Phe Phe Phe Arg Trp
                  80                  85                  90

 Trp Leu Gln Val Thr Ser Lys Val Ile Phe Phe Trp Leu Leu Val
                  95                 100                 105

 Leu Tyr Leu Leu Gln Val Ala Ala Ile Val Leu Phe Cys Ser Thr
                 110                 115                 120

 Ser Ser Pro His Ser Ile Pro Leu Thr Glu Val Ile Gly Pro Ile
                 125                 130                 135

 Trp Leu Met Leu Leu Leu Gly Thr Val His Cys Gln Ile Val Ser
                 140                 145                 150

 Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr Gly Gly Lys Arg Arg
                 155                 160                 165

 Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val His Arg Glu Gly
                 170                 175                 180

 Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly Ala Val Gln
                 185                 190                 195

 Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val Phe Arg
                 200                 205                 210

 Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys Ala
                 215                 220                 225

 Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val
                 230                 235                 240

 Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile
                 245                 250                 255

 Gln Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr
                 260                 265                 270

 Ala Trp Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr
                 275                 280                 285

 Gln Arg Thr Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu
                 290                 295                 300

 Gly Pro Glu Thr Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr
                 305                 310                 315

 Ser Glu Gly Val Leu Arg Asn Arg Lys Ser His His Tyr Lys Lys
                 320                 325                 330

 His Tyr Pro Asn Glu Asp Ala Pro Lys Ser Gly Thr Ser Cys Ser
                 335                 340                 345

 Ser Arg Cys Ser Ser Ser Arg Gln Asp Ser Glu Ser Ala Arg Pro
                 350                 355                 360

 Glu Ser Glu Thr Glu Asp Val Leu Trp Glu Asp Leu Leu His Cys
                 365                 370                 375

 Ala Glu Cys His Ser Ser Cys Thr Ser Glu Thr Asp Val Glu Asn
                 380                 385                 390

 His Gln Ile Asn Pro Cys Val Lys Lys Glu Tyr Arg Asp Asp Pro
                 395                 400                 405

 Phe His Gln Ser His Leu Pro Trp Leu His Ser Ser His Pro Gly
                 410                 415                 420

 Leu Glu Lys Ile Ser Ala Ile Val Trp Glu Gly Asn Asp Cys Lys
                 425                 430                 435

 Lys Ala Asp Met Ser Val Leu Glu Ile Ser Gly Met Ile Met Asn
                 440                 445                 450

 Arg Val Asn Ser His Ile Pro Gly Ile Gly Tyr Gln Ile Phe Gly
                 455                 460                 465

 Asn Ala Val Ser Leu Ile Leu Gly Leu Thr Pro Phe Val Phe Arg
                 470                 475                 480

 Leu Ser Gln Ala Thr Asp Leu Glu Gln Leu Thr Ala His Ser Ala
                 485                 490                 495

 Ser Glu Leu Tyr Val Ile Ala Phe Gly Ser Asn Glu Asp Val Ile
                 500                 505                 510

 Val Leu Ser Met Val Ile Ile Ser Phe Val Val Arg Val Ser Leu
                 515                 520                 525

 Val Trp Ile Phe Phe Phe Leu Leu Cys Val Ala Glu Arg Thr Tyr
                 530                 535                 540

 Lys Gln Arg Leu Leu Phe Ala Lys Leu Phe Gly His Leu Thr Ser
                 545                 550                 555

 Ala Arg Arg Ala Arg Lys Ser Glu Val Pro His Phe Arg Leu Lys
                 560                 565                 570

 Lys Val Gln Asn Ile Lys Met Trp Leu Ser Leu Arg Ser Tyr Leu
                 575                 580                 585

 Lys Arg Arg Gly Pro Gln Arg Ser Val Asp Val Ile Val Ser Ser
                 590                 595                 600

 Ala Phe Leu Leu Thr Ile Ser Val Val Phe Ile Cys Cys Ala Gln
                 605                 610                 615

 Ile Asn Leu Tyr Leu Lys Met Glu Lys Lys Pro Asn Lys Lys Glu
                 620                 625                 630

 Glu Leu Thr Leu Val Asn Asn Val Leu Lys Leu Ala Thr Lys Leu
                 635                 640                 645

 Leu Lys Glu Leu Asp Ser Pro Phe Arg Leu Tyr Gly Leu Thr Met
                 650                 655                 660

 Asn Pro Leu Leu Tyr Asn Ile Thr Gln Val Val Ile Leu Ser Ala
                 665                 670                 675

 Val Ser Gly Val Ile Ser Asp Leu Leu Gly Phe Asn Leu Lys Leu
                 680                 685                 690

 Trp Lys Ile Lys Ser
                 695

<210> 2094
<211> 4845
<212> DNA
<213> Homo sapien

<400> 2094
 gcacgagagc taggccggcg gcagtggtgg tggcggcggc gcaagggtga 50

 gggcggcccc agaaccccag gtaggtagag caagaagatg gtgtttctgc 100

 ccctcaaatg gtcccttgca accatgtcat ttctactttc ctcactgttg 150

 gctctcttaa ctgtgtccac tccttcatgg tgtcagagca ctgaagcatc 200

 tccaaaacgt agtgatggga caccatttcc ttggaataaa atacgacttc 250

 ctgagtacgt catcccagtt cattatgatc tcttgatcca tgcaaacctt 300

 accacgctga ccttctgggg aaccacgaaa gtagaaatca cagccagtca 350

 gcccaccagc accatcatcc tgcatagtca ccacctgcag atatctaggg 400

 ccaccctcag gaagggagct ggagagaggc tatcggaaga acccctgcag 450

 gtcctggaac acccccgtca ggagcaaatt gcactgctgg ctcccgagcc 500

 cctccttgtc gggctcccgt acacagttgt cattcactat gctggcaatc 550

 tttcggagac tttccacgga ttttacaaaa gcacctacag aaccaaggaa 600

 ggggaactga ggatactagc atcaacacaa tttgaaccca ctgcagctag 650

 aatggccttt ccctgctttg atgaacctgc cttcaaagca agtttctcaa 700

 tcaaaattag aagagagcca aggcacctag ccatctccaa tatgccattg 750

 gtgaaatctg tgactgttgc tgaaggactc atagaagacc attttgatgt 800

 cactgtgaag atgagcacct atctggtggc cttcatcatt tcagattttg 850

 agtctgtcag caagataacc aagagtggag tcaaggtttc tgtttatgct 900

 gtgccagaca agataaatca agcagattat gcactggatg ctgcggtgac 950

 tcttctagaa ttttatgagg attatttcag cataccgtat cccctaccca 1000

 aacaagatct tgctgctatt cccgactttc agtctggtgc tatggaaaac 1050

 tggggactga caacatatag agaatctgct ctgttgtttg atgcagaaaa 1100

 gtcttctgca tcaagtaagc ttggcatcac aatgactgtg gcccatgaac 1150

 tggctcacca gtggtttggg aacctggtca ctatggaatg gtggaatgat 1200

 ctttggctaa atgaaggatt tgccaaattt atggagtttg tgtctgtcag 1250

 tgtgacccat cctgaactga aagttggaga ttatttcttt ggcaaatgtt 1300

 ttgacgcaat ggaggtagat gctttaaatt cctcacaccc tgtgtctaca 1350

 cctgtggaaa atcctgctca gatccgggag atgtttgatg atgtttctta 1400

 tgataaggga gcttgtattc tgaatatgct aagggagtat cttagtgctg 1450

 acgcatttaa aagtggtatt gtacagtatc tccagaagca tagctataaa 1500

 aatacaaaaa acgaggacct gtgggatagt atggcaagta tttgccctac 1550

 agatggtgta aaagggatgg atggcttttg ctctagaagt caacattcat 1600

 cttcatcctc acattggcat caggaagggg tggatgtgaa aaccatgatg 1650

 aacacttgga cactgcagaa gggttttccc ctaataacca tcacagtgag 1700

 ggggaggaat gtacacatga agcaagagca ctacatgaag ggctctgacg 1750

 gcgccccgga cactgggtac ctgtggcatg ttccattgac attcatcacc 1800

 agcaaatccg acatggtcca tcgatttttg ctaaaaacaa aaacagatgt 1850

 gctcatcctc ccagaagagg tggaatggat caaatttaat gtgggcatga 1900

 atggctatta cattgtgcat tacgaggatg atggatggga ctctttgact 1950

 ggccttttaa aaggaacaca cacagcagtc agcagtaatg atcgggcgag 2000

 tctcattaac aatgcatttc agctcgtcag cattgggaag ctgtccattg 2050

 aaaaggcctt ggatttatcc ctgtacttga aacatgaaac tgaaattatg 2100

 cccgtgtttc aaggtttgaa tgagctgatt cctatgtata agttaatgga 2150

 gaaaagagat atgaatgaag tggaaactca attcaaggcc ttcctcatca 2200

 ggctgctaag ggacctcatt gataagcaga catggacaga cgagggctca 2250

 gtctcagagc gaatgctgcg gagtcaacta ctactcctcg cctgtgtgca 2300

 caactatcag ccgtgcgtac agagggcaga aggctatttc agaaagtgga 2350

 aggaatccaa tggaaacttg agcctgcctg tcgacgtgac cttggcagtg 2400

 tttgctgtgg gggcccagag cacagaaggc tgggattttc tttatagtaa 2450

 atatcagttt tctttgtcca gtactgagaa aagccaaatt gaatttgccc 2500

 tctgcagaac ccaaaataag gaaaagcttc aatggctact agatgaaagc 2550

 tttaagggag ataaaataaa aactcaggag tttccacaaa ttcttacact 2600

 cattggcagg aacccagtag gatacccact ggcctggcaa tttctgagga 2650

 aaaactggaa caaacttgta caaaagtttg aacttggctc atcttccata 2700

 gcccacatgg taatgggtac aacaaatcaa ttctccacaa gaacacggct 2750

 tgaagaggta aaaggattct tcagctcttt gaaagaaaat ggttctcagc 2800

 tccgttgtgt ccaacagaca attgaaacca ttgaagaaaa catcggttgg 2850

 atggataaga attttgataa aatcagagtg tggctgcaaa gtgaaaagct 2900

 tgaacgtatg taaaaattcc tcccttgcca ggttcctgtt atctctaatc 2950

 accaacattt tgttgagtgt attttcaaac tagagatggc tgttttggct 3000

 ccaactggag atactttttt cccttcaact cattttttga ctatccctgt 3050

 gaaaagaata gctgttagtt tttcatgaat gggctatcgc taccatgtgt 3100

 tttgttcatc acaggtgttg ccctgcaacg taaacccaag tgttgggttc 3150

 cctgccacag aagaataaag taccttattc ttctcatttt atagtttatg 3200

 cttaagcacc cgtgtccaaa accctgtacc ccatgtttat cattcataaa 3250

 ctgtttcatc agtctcctcg aaagactctg aatagtcgac tactgaacaa 3300

 tgaacacctg gatctgagac taagccggac gatgactggg ttaaagctct 3350

 cccggctcac ccctccagac ccgctgccca tccctcttcc ttgctccatg 3400

 cccaggggct gacttgtaaa ggccaagtca tcaagctttc ttgccctttg 3450

 gatgttggtc agtggggagc cggagagctg gagctggggt cggaggaggt 3500

 agtaggtgga ggtgttcttc cctgattccc ttgcgggatg cctcgggctg 3550

 gcctcccctg agggttttag ctccgagagg ggaccctctt ttccacacag 3600

 ccttctccac ctctggattt tggtaactgc tccctcctca tcccttcagg 3650

 attagtggcc tcagtgggag tctggctttt actagtcctg gcggacttgt 3700

 ggtttctaca taatgtgctc gcacttttgc aaaaaatctt ctttttatag 3750

 aaccctcctc agataattct gagtgtcatc tatttccctg actggtacag 3800

 tatctcttct gaaaaagcag agtgcattca agtctgtagg aaaacccttt 3850

 tcttagggag gtgatttttt ttctctctct gcttcttatt tggcctactt 3900

 tacaatttct aactaactag ttattggcat ttactgacag taaattattg 3950

 cagtcaccaa taaatgatag tacattgtga aacaaaatat ttgctcatat 4000

 tagcaaatag gacattcttt ggctttgaag tctttctttt gtgaagactt 4050

 cacacacggt tgcttcagca cacagttgct gctcaggttt tatgtataga 4100

 tgataataat agaaagcaca gtttactaac atggtaaacc aacggagttc 4150

 aagtcaagtc agttaatacc ctaagaatta gattttattt cttattctga 4200

 aaacttgcta cacagggact tatctaaccc atagtgtgct ctgttgctga 4250

 cttgattcaa gttgcagcgt gttttgcgct gactctaagg tgcggaaatc 4300

 ctcacacctg gcaaaggaga attcaaactg aactttttga atataaggca 4350

 aaaacttcaa gataagggaa tatgattgat gattggtacg aaaaatgtca 4400

 aaatgtgttc ccctaataca cgacaaaata gagtgacttc tggacataaa 4450

 tctgccattt attaaaccat tcactacaac aaataaatag gtataaaagt 4500

 ggaattggaa tttttatact tatttgttgt agtgaatggt ttaataaaaa 4550

 tagaaatcac tggtaatttc caccccaaac taaactattt cccttctttt 4600

 aaaaaaatac acaaccaaga ttttaatgta aaatattttg ctttaattgt 4650

 attttatgcc ttgattaatg aaacatggaa atattgattt tcagttttgg 4700

 tcacctgagg aacctatctt tgtttgcttt tggaaaagcc cattttctaa 4750

 acagatacaa tattgccaca acaatgtgca gaaacctttt tgataataaa 4800

 aaattgttct ttgcctctaa aaaaaaaaaa aaaaaaaaaa aaaaa 4845

<210> 2095
<211> 941
<212> PRT
<213> Homo sapien

<400> 2095
 Met Val Phe Leu Pro Leu Lys Trp Ser Leu Ala Thr Met Ser Phe
   1               5                  10                  15

 Leu Leu Ser Ser Leu Leu Ala Leu Leu Thr Val Ser Thr Pro Ser
                  20                  25                  30

 Trp Cys Gln Ser Thr Glu Ala Ser Pro Lys Arg Ser Asp Gly Thr
                  35                  40                  45

 Pro Phe Pro Trp Asn Lys Ile Arg Leu Pro Glu Tyr Val Ile Pro
                  50                  55                  60

 Val His Tyr Asp Leu Leu Ile His Ala Asn Leu Thr Thr Leu Thr
                  65                  70                  75

 Phe Trp Gly Thr Thr Lys Val Glu Ile Thr Ala Ser Gln Pro Thr
                  80                  85                  90

 Ser Thr Ile Ile Leu His Ser His His Leu Gln Ile Ser Arg Ala
                  95                 100                 105

 Thr Leu Arg Lys Gly Ala Gly Glu Arg Leu Ser Glu Glu Pro Leu
                 110                 115                 120

 Gln Val Leu Glu His Pro Arg Gln Glu Gln Ile Ala Leu Leu Ala
                 125                 130                 135

 Pro Glu Pro Leu Leu Val Gly Leu Pro Tyr Thr Val Val Ile His
                 140                 145                 150

 Tyr Ala Gly Asn Leu Ser Glu Thr Phe His Gly Phe Tyr Lys Ser
                 155                 160                 165

 Thr Tyr Arg Thr Lys Glu Gly Glu Leu Arg Ile Leu Ala Ser Thr
                 170                 175                 180

 Gln Phe Glu Pro Thr Ala Ala Arg Met Ala Phe Pro Cys Phe Asp
                 185                 190                 195

 Glu Pro Ala Phe Lys Ala Ser Phe Ser Ile Lys Ile Arg Arg Glu
                 200                 205                 210

 Pro Arg His Leu Ala Ile Ser Asn Met Pro Leu Val Lys Ser Val
                 215                 220                 225

 Thr Val Ala Glu Gly Leu Ile Glu Asp His Phe Asp Val Thr Val
                 230                 235                 240

 Lys Met Ser Thr Tyr Leu Val Ala Phe Ile Ile Ser Asp Phe Glu
                 245                 250                 255

 Ser Val Ser Lys Ile Thr Lys Ser Gly Val Lys Val Ser Val Tyr
                 260                 265                 270

 Ala Val Pro Asp Lys Ile Asn Gln Ala Asp Tyr Ala Leu Asp Ala
                 275                 280                 285

 Ala Val Thr Leu Leu Glu Phe Tyr Glu Asp Tyr Phe Ser Ile Pro
                 290                 295                 300

 Tyr Pro Leu Pro Lys Gln Asp Leu Ala Ala Ile Pro Asp Phe Gln
                 305                 310                 315

 Ser Gly Ala Met Glu Asn Trp Gly Leu Thr Thr Tyr Arg Glu Ser
                 320                 325                 330

 Ala Leu Leu Phe Asp Ala Glu Lys Ser Ser Ala Ser Ser Lys Leu
                 335                 340                 345

 Gly Ile Thr Met Thr Val Ala His Glu Leu Ala His Gln Trp Phe
                 350                 355                 360

 Gly Asn Leu Val Thr Met Glu Trp Trp Asn Asp Leu Trp Leu Asn
                 365                 370                 375

 Glu Gly Phe Ala Lys Phe Met Glu Phe Val Ser Val Ser Val Thr
                 380                 385                 390

 His Pro Glu Leu Lys Val Gly Asp Tyr Phe Phe Gly Lys Cys Phe
                 395                 400                 405

 Asp Ala Met Glu Val Asp Ala Leu Asn Ser Ser His Pro Val Ser
                 410                 415                 420

 Thr Pro Val Glu Asn Pro Ala Gln Ile Arg Glu Met Phe Asp Asp
                 425                 430                 435

 Val Ser Tyr Asp Lys Gly Ala Cys Ile Leu Asn Met Leu Arg Glu
                 440                 445                 450

 Tyr Leu Ser Ala Asp Ala Phe Lys Ser Gly Ile Val Gln Tyr Leu
                 455                 460                 465

 Gln Lys His Ser Tyr Lys Asn Thr Lys Asn Glu Asp Leu Trp Asp
                 470                 475                 480

 Ser Met Ala Ser Ile Cys Pro Thr Asp Gly Val Lys Gly Met Asp
                 485                 490                 495

 Gly Phe Cys Ser Arg Ser Gln His Ser Ser Ser Ser Ser His Trp
                 500                 505                 510

 His Gln Glu Gly Val Asp Val Lys Thr Met Met Asn Thr Trp Thr
                 515                 520                 525

 Leu Gln Lys Gly Phe Pro Leu Ile Thr Ile Thr Val Arg Gly Arg
                 530                 535                 540

 Asn Val His Met Lys Gln Glu His Tyr Met Lys Gly Ser Asp Gly
                 545                 550                 555

 Ala Pro Asp Thr Gly Tyr Leu Trp His Val Pro Leu Thr Phe Ile
                 560                 565                 570

 Thr Ser Lys Ser Asp Met Val His Arg Phe Leu Leu Lys Thr Lys
                 575                 580                 585

 Thr Asp Val Leu Ile Leu Pro Glu Glu Val Glu Trp Ile Lys Phe
                 590                 595                 600

 Asn Val Gly Met Asn Gly Tyr Tyr Ile Val His Tyr Glu Asp Asp
                 605                 610                 615

 Gly Trp Asp Ser Leu Thr Gly Leu Leu Lys Gly Thr His Thr Ala
                 620                 625                 630

 Val Ser Ser Asn Asp Arg Ala Ser Leu Ile Asn Asn Ala Phe Gln
                 635                 640                 645

 Leu Val Ser Ile Gly Lys Leu Ser Ile Glu Lys Ala Leu Asp Leu
                 650                 655                 660

 Ser Leu Tyr Leu Lys His Glu Thr Glu Ile Met Pro Val Phe Gln
                 665                 670                 675

 Gly Leu Asn Glu Leu Ile Pro Met Tyr Lys Leu Met Glu Lys Arg
                 680                 685                 690

 Asp Met Asn Glu Val Glu Thr Gln Phe Lys Ala Phe Leu Ile Arg
                 695                 700                 705

 Leu Leu Arg Asp Leu Ile Asp Lys Gln Thr Trp Thr Asp Glu Gly
                 710                 715                 720

 Ser Val Ser Glu Arg Met Leu Arg Ser Gln Leu Leu Leu Leu Ala
                 725                 730                 735

 Cys Val His Asn Tyr Gln Pro Cys Val Gln Arg Ala Glu Gly Tyr
                 740                 745                 750

 Phe Arg Lys Trp Lys Glu Ser Asn Gly Asn Leu Ser Leu Pro Val
                 755                 760                 765

 Asp Val Thr Leu Ala Val Phe Ala Val Gly Ala Gln Ser Thr Glu
                 770                 775                 780

 Gly Trp Asp Phe Leu Tyr Ser Lys Tyr Gln Phe Ser Leu Ser Ser
                 785                 790                 795

 Thr Glu Lys Ser Gln Ile Glu Phe Ala Leu Cys Arg Thr Gln Asn
                 800                 805                 810

 Lys Glu Lys Leu Gln Trp Leu Leu Asp Glu Ser Phe Lys Gly Asp
                 815                 820                 825

 Lys Ile Lys Thr Gln Glu Phe Pro Gln Ile Leu Thr Leu Ile Gly
                 830                 835                 840

 Arg Asn Pro Val Gly Tyr Pro Leu Ala Trp Gln Phe Leu Arg Lys
                 845                 850                 855

 Asn Trp Asn Lys Leu Val Gln Lys Phe Glu Leu Gly Ser Ser Ser
                 860                 865                 870

 Ile Ala His Met Val Met Gly Thr Thr Asn Gln Phe Ser Thr Arg
                 875                 880                 885

 Thr Arg Leu Glu Glu Val Lys Gly Phe Phe Ser Ser Leu Lys Glu
                 890                 895                 900

 Asn Gly Ser Gln Leu Arg Cys Val Gln Gln Thr Ile Glu Thr Ile
                 905                 910                 915

 Glu Glu Asn Ile Gly Trp Met Asp Lys Asn Phe Asp Lys Ile Arg
                 920                 925                 930

 Val Trp Leu Gln Ser Glu Lys Leu Glu Arg Met
                 935                 940

<210> 2096
<211> 1661
<212> DNA
<213> Homo sapien

<400> 2096
 ccgagggcgg ggccgggccc gggagcctgt ggcttcagga agaggagggc 50

 aaggtgtctg gctgcgcgtt tggctgcaat gagctcggcc tcggggctcc 100

 gcagggggca cccggcaggt ggggaagaaa acatgacaga aacagatgcc 150

 ttctataaaa gagaaatgtt tgatccggca gaaaagtaca aaatggacca 200

 caggaggaga ggaattgctt taatcttcaa tcatgagagg ttcttttggc 250

 acttaacact gccagaaagg cggggcacct gcgcagatag agacaatctt 300

 acccgcaggt tttcagatct aggatttgaa gtgaaatgct ttaatgatct 350

 taaagcagaa gaactactgc tcaaaattca tgaggtgtca actgttagcc 400

 acgcagatgc cgattgcttt gtgtgtgtct tcctgagcca tggcgaaggc 450

 aatcacattt atgcatatga tgctaaaatc gaaattcaga cattaactgg 500

 cttgttcaaa ggagacaagt gtcacagcct ggttggaaaa cccaagatat 550

 ttatcattca ggcatgtcgg ggaaaccagc acgatgtgcc agtcattcct 600

 ttggatgtag tagataatca gacagagaag ttggacacca acataactga 650

 ggtggatgca gcctccgttt acacgctgcc tgctggagct gacttcctca 700

 tgtgttactc tgttgcagaa ggatattatt ctcaccggga aactgtgaac 750

 ggctcatggt acattcaaga tttgtgtgag atgttgggaa aatatggctc 800

 ctccttagag ttcacagaac tcctcacact ggtgaacagg aaagtttctc 850

 agcgccgagt ggacttttgc aaagacccaa gtgcaattgg aaagaagcag 900

 gttccctgtt ttgcctcaat gctaactaaa aagctgcatt tctttccaaa 950

 atctaattaa ttaatagagg ctatctaatt ccacactctg tattgaaaat 1000

 ggctttctca gccaggcgtg gttactcaca cctgtaatcc cagcactttg 1050

 ggagtccaag gtgggcggat cacctgaggt cgggagttcg agaccagcct 1100

 gaccaacatg gagaagcccc gtctctacta aaaatgcaaa aaaaaattta 1150

 gctaggcatg gcggcgcatg cctgcaatcc cagctacttg gaaggctgag 1200

 gcaggagaat cacttgaacc caggaggtgg aggctgcggt gagccgagat 1250

 tgcgccattg cactccagcc tgggcaacga gtgaaactcc gtctcaaaaa 1300

 aaagaaaatg tctttctctt ccttttatat aaatatcgtt agggtgaagc 1350

 attatggtct aatgattcaa atgttttaaa gtttaatgcc tagcagagaa 1400

 ctgccttaaa aaaaaaaaaa aaaagttcat gttggccatg gtgaaagggt 1450

 ttgatatgga gaaacaaaat cctcaggaaa ttagataaat aaaaatttat 1500

 aagcatttgt attatttttt aataaactgc agggttacac aaaaatctag 1550

 ctgatttaac ttgtattttg tcactttttt ataaaagttt attgtttgat 1600

 gtttttaaag gtttttgaaa tccaggaatt aaatcatccc ttaataaaat 1650

 attcgaaatt c 1661

<210> 2097
<211> 293
<212> PRT
<213> Homo sapien

<400> 2097
 Met Ser Ser Ala Ser Gly Leu Arg Arg Gly His Pro Ala Gly Gly
   1               5                  10                  15

 Glu Glu Asn Met Thr Glu Thr Asp Ala Phe Tyr Lys Arg Glu Met
                  20                  25                  30

 Phe Asp Pro Ala Glu Lys Tyr Lys Met Asp His Arg Arg Arg Gly
                  35                  40                  45

 Ile Ala Leu Ile Phe Asn His Glu Arg Phe Phe Trp His Leu Thr
                  50                  55                  60

 Leu Pro Glu Arg Arg Gly Thr Cys Ala Asp Arg Asp Asn Leu Thr
                  65                  70                  75

 Arg Arg Phe Ser Asp Leu Gly Phe Glu Val Lys Cys Phe Asn Asp
                  80                  85                  90

 Leu Lys Ala Glu Glu Leu Leu Leu Lys Ile His Glu Val Ser Thr
                  95                 100                 105

 Val Ser His Ala Asp Ala Asp Cys Phe Val Cys Val Phe Leu Ser
                 110                 115                 120

 His Gly Glu Gly Asn His Ile Tyr Ala Tyr Asp Ala Lys Ile Glu
                 125                 130                 135

 Ile Gln Thr Leu Thr Gly Leu Phe Lys Gly Asp Lys Cys His Ser
                 140                 145                 150

 Leu Val Gly Lys Pro Lys Ile Phe Ile Ile Gln Ala Cys Arg Gly
                 155                 160                 165

 Asn Gln His Asp Val Pro Val Ile Pro Leu Asp Val Val Asp Asn
                 170                 175                 180

 Gln Thr Glu Lys Leu Asp Thr Asn Ile Thr Glu Val Asp Ala Ala
                 185                 190                 195

 Ser Val Tyr Thr Leu Pro Ala Gly Ala Asp Phe Leu Met Cys Tyr
                 200                 205                 210

 Ser Val Ala Glu Gly Tyr Tyr Ser His Arg Glu Thr Val Asn Gly
                 215                 220                 225

 Ser Trp Tyr Ile Gln Asp Leu Cys Glu Met Leu Gly Lys Tyr Gly
                 230                 235                 240

 Ser Ser Leu Glu Phe Thr Glu Leu Leu Thr Leu Val Asn Arg Lys
                 245                 250                 255

 Val Ser Gln Arg Arg Val Asp Phe Cys Lys Asp Pro Ser Ala Ile
                 260                 265                 270

 Gly Lys Lys Gln Val Pro Cys Phe Ala Ser Met Leu Thr Lys Lys
                 275                 280                 285

 Leu His Phe Phe Pro Lys Ser Asn
                 290

<210> 2098
<211> 1702
<212> DNA
<213> Homo sapien

<400> 2098
 agactcaaca agagctccag caaagacttt cactgtagct tgacttgacc 50

 tgagattaac tagggaatct tgagaataaa gatgagctct gaaaattgtt 100

 tcgtagcaga gaacagctct ttgcatccgg agagtggaca agaaaatgat 150

 gccaccagtc cccatttctc aacacgtcat gaagggtcct tccaagttcc 200

 tgtcctgtgt gctgtaatga atgtggtctt catcaccatt ttaatcatag 250

 ctctcattgc cttatcagtg ggccaataca attgtccagg ccaatacaca 300

 ttctcaatgc catcagacag ccatgtttct tcatgctctg aggactgggt 350

 tggctaccag aggaaatgct actttatttc tactgtgaag aggagctgga 400

 cttcagccca aaatgcttgt tctgaacatg gtgctactct tgctgtcatt 450

 gattctgaaa aggacatgaa ctttctaaaa cgatacgcag gtagagagga 500

 acactgggtt ggactgaaaa aggaacctgg tcacccatgg aagtggtcaa 550

 atggcaaaga atttaacaac tggttcaacg ttacagggtc tgacaagtgt 600

 gtttttctga aaaacacaga ggtcagcagc atggaatgtg agaagaattt 650

 atactggata tgtaacaaac cttacaaata ataaggaaac atgttcactt 700

 attgactatt atagaatgga actcaaggaa atctgtgtca gtggatgctg 750

 ctctgtggtc cgaagtcttc catagagact ttgtgaaaaa aaattttata 800

 gtgtcttggg aattttcttc caaacagaac tatggaaaaa aaggaagaaa 850

 ttccaggaaa atctgcactg tgggctttta ttgccatgag ctagaagcat 900

 cacaggttga ccaataacca tgcccaagaa tgagaagaat gactatgcaa 950

 cctttggatg cactttatat tattttgaat ccagaaataa tgaaataact 1000

 aggcgtggac ttactattta ttgctgaatg actaccaaca gtgagagccc 1050

 ttcatgcatt tgcactactg gaaggagtta gatgttggta ctagatactg 1100

 aatgtaaaca aaggaattat ggctggtaac ataggttttt agtctaattg 1150

 aatcccttaa actcagggag catttataaa tggacaaatg cttatgaaac 1200

 taagatttgt aatatttctc tctttttaga gaaatttgcc aatttacttt 1250

 gttatttttc cccaaaaaga atgggatgat cgtgtattta tttttttact 1300

 tcctcagctg tagacaggtc cttttcgatg gtacatattt ctttgccttt 1350

 ataatctttt atacagtgtc ttacagagaa aagacataag caaagactat 1400

 gaggaatatt tgcaagacat agaatagtgt tggaaaatgt gcaatatgtg 1450

 atgtggcaaa tctctattag gaaatattct gtaatcttca gacctagaat 1500

 aatactagtc ttataatagg tttgtgactt tcctaaatca attctattac 1550

 gtgcaatact tcaatacttc atttaaaata tttttatgtg caataaaatg 1600

 tatttgtttg tattttgtgt tcagtacaat tataagctgt ttttatatat 1650

 gtgaaataaa agtagaataa acacaaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aa 1702

<210> 2099
<211> 199
<212> PRT
<213> Homo sapien

<400> 2099
 Met Ser Ser Glu Asn Cys Phe Val Ala Glu Asn Ser Ser Leu His
   1               5                  10                  15

 Pro Glu Ser Gly Gln Glu Asn Asp Ala Thr Ser Pro His Phe Ser
                  20                  25                  30

 Thr Arg His Glu Gly Ser Phe Gln Val Pro Val Leu Cys Ala Val
                  35                  40                  45

 Met Asn Val Val Phe Ile Thr Ile Leu Ile Ile Ala Leu Ile Ala
                  50                  55                  60

 Leu Ser Val Gly Gln Tyr Asn Cys Pro Gly Gln Tyr Thr Phe Ser
                  65                  70                  75

 Met Pro Ser Asp Ser His Val Ser Ser Cys Ser Glu Asp Trp Val
                  80                  85                  90

 Gly Tyr Gln Arg Lys Cys Tyr Phe Ile Ser Thr Val Lys Arg Ser
                  95                 100                 105

 Trp Thr Ser Ala Gln Asn Ala Cys Ser Glu His Gly Ala Thr Leu
                 110                 115                 120

 Ala Val Ile Asp Ser Glu Lys Asp Met Asn Phe Leu Lys Arg Tyr
                 125                 130                 135

 Ala Gly Arg Glu Glu His Trp Val Gly Leu Lys Lys Glu Pro Gly
                 140                 145                 150

 His Pro Trp Lys Trp Ser Asn Gly Lys Glu Phe Asn Asn Trp Phe
                 155                 160                 165

 Asn Val Thr Gly Ser Asp Lys Cys Val Phe Leu Lys Asn Thr Glu
                 170                 175                 180

 Val Ser Ser Met Glu Cys Glu Lys Asn Leu Tyr Trp Ile Cys Asn
                 185                 190                 195

 Lys Pro Tyr Lys


<210> 2100
<211> 913
<212> DNA
<213> Homo sapien

<400> 2100
 agagccggcg ccgtcaccgc ccgcattgcc gctcccagtc ccgcgctcgg 50

 cacgacatga aatcccccga cgaggtgcta cgcgagggcg agttggagaa 100

 gcgcagcgac agcctcttcc agctatggaa gaagaagcgc ggggtgctca 150

 cctccgaccg cctgagcctg ttccccgcca gcccccgcgc gcgccccaag 200

 gagctgcgct tccactccat cctcaaggtg gactgcgtgg agcgcacggg 250

 caagtacgtg tacttcacca tcgtcaccac cgaccacaag gagatcgact 300

 tccgctgcgc gggcgagagc tgctggaacg cggccatcgc gctggcgctc 350

 atcgatttcc agaaccgccg cgccctgcag gactttcgca gccgccagga 400

 acgcaccgca cccgccgcac ccgccgagga cgccgtggct gccgcggccg 450

 ccgcaccctc cgagccctcg gagccctcca ggccatcccc gcagcccaaa 500

 ccccgcacgc catgagcccg ccgcgggcca tacgctggac gagtcggacc 550

 gaggctagga cgtggccggc gctctccagc cctgcagcag aagaacttcc 600

 cgtgcgcgcg gatcctcgct ccgttgcacg ggcgccttaa gttattggac 650

 tatctaatat ctatgtattt atttcgctgg ttctttgtag tcacatattt 700

 tatagtctta atatcttgtt tttgcatcac tgtgcccatt gcaaataaat 750

 cacttggcca gtttgctttt ctaccatccg gctgtggctc agtgagactc 800

 ctgctgggag ggtggaggcc caggaatggg cgggcaggac accctcatcc 850

 agtcctgcgg ggctggtgtg aaaggcgctg ggaaccggct ttgaatgaat 900

 aaatgaatcg tgt 913

<210> 2101
<211> 152
<212> PRT
<213> Homo sapien

<400> 2101
 Met Lys Ser Pro Asp Glu Val Leu Arg Glu Gly Glu Leu Glu Lys
   1               5                  10                  15

 Arg Ser Asp Ser Leu Phe Gln Leu Trp Lys Lys Lys Arg Gly Val
                  20                  25                  30

 Leu Thr Ser Asp Arg Leu Ser Leu Phe Pro Ala Ser Pro Arg Ala
                  35                  40                  45

 Arg Pro Lys Glu Leu Arg Phe His Ser Ile Leu Lys Val Asp Cys
                  50                  55                  60

 Val Glu Arg Thr Gly Lys Tyr Val Tyr Phe Thr Ile Val Thr Thr
                  65                  70                  75

 Asp His Lys Glu Ile Asp Phe Arg Cys Ala Gly Glu Ser Cys Trp
                  80                  85                  90

 Asn Ala Ala Ile Ala Leu Ala Leu Ile Asp Phe Gln Asn Arg Arg
                  95                 100                 105

 Ala Leu Gln Asp Phe Arg Ser Arg Gln Glu Arg Thr Ala Pro Ala
                 110                 115                 120

 Ala Pro Ala Glu Asp Ala Val Ala Ala Ala Ala Ala Ala Pro Ser
                 125                 130                 135

 Glu Pro Ser Glu Pro Ser Arg Pro Ser Pro Gln Pro Lys Pro Arg
                 140                 145                 150

 Thr Pro


<210> 2102
<211> 1530
<212> DNA
<213> Homo sapien

<400> 2102
 gtgaggacac cgctttacaa cgatgcaggg ggccccatgt caccctcacc 50

 catgggaagt ttgacttggt ggactcagcc aagccacaga ggtctaacgc 100

 ttctctgcgg tgatttcagg ctgccctggc agaaagcaca gtgcctgcag 150

 acatgctgtc actgctccac gcatcaacgc tggcagtcct tggggctctg 200

 tgtgtatatg gtgcaggtca cctagagcaa cctcaaattt ccagtactaa 250

 aacgctgtca aaaacagccc gcctggaatg tgtggtgtct ggaataacaa 300

 tttctgcaac atctgtatat tggtatcgag agagacctgg tgaagtcata 350

 cagttcctgg tgtccatttc atatgacggc actgtcagaa aggaatccgg 400

 cattccgtca ggcaaatttg aggtggatag gatacctgaa acgtctacat 450

 ccactctcac cattcacaat gtagagaaac aggacatagc tacctactac 500

 tgtgccttgt tggagggaaa ttataagaaa ctctttggca gtggaacaac 550

 acttgttgtc acagataaac aacttgatgc agatgtttcc cccaagccca 600

 ctatttttct tccttcaatt gctgaaacaa agctccagaa ggctggaaca 650

 tacctttgtc ttcttgagaa atttttccct gatgttatta agatacattg 700

 gcaagaaaag aagagcaaca cgattctggg atcccaggag gggaacacca 750

 tgaagactaa cgacacatac atgaaattta gctggttaac ggtgccagaa 800

 aagtcactgg acaaagaaca cagatgtatc gtcagacatg agaataataa 850

 aaacggagtt gatcaagaaa ttatctttcc tccaataaag acagatgtca 900

 tcacaatgga tcccaaagac aattgttcaa aagatgcaaa tgatacacta 950

 ctgctgcagc tcacaaacac ctctgcatat tacatgtacc tcctcctgct 1000

 cctcaagagt gtggtctatt ttgccatcat cacctgctgt ctgcttagaa 1050

 gaacggcttt ctgctgcaat ggagagaaat cataacagac ggtggcacaa 1100

 ggaggccatc ttttcctcat cggttattgt ccctagaagc gtcttctgag 1150

 gatctagttg ggctttcttt ctgggtttgg gccatttcag ttctcatgtg 1200

 tgtactattc tatcattatt gtataacggt tttcaaacca gtgggcacac 1250

 agagaacctc actctgtaat aacaatgagg aatagccacg gcgatctcca 1300

 gcaccaatct ctccatgttt tccacagctc ctccagccaa cccaaatagc 1350

 gcctgctata gtgtagacat cctgcggctt ctagccttgt ccctctctta 1400

 gtgttcttta atcagataac tgcctggaag cctttcattt tacacgccct 1450

 gaagcagtct tctttgctag ttgaattatg tggtgtgttt ttccgtaata 1500

 agcaaaataa atttaaaaaa atgaaaagtt 1530

<210> 2103
<211> 310
<212> PRT
<213> Homo sapien

<400> 2103
 Met Leu Ser Leu Leu His Ala Ser Thr Leu Ala Val Leu Gly Ala
   1               5                  10                  15

 Leu Cys Val Tyr Gly Ala Gly His Leu Glu Gln Pro Gln Ile Ser
                  20                  25                  30

 Ser Thr Lys Thr Leu Ser Lys Thr Ala Arg Leu Glu Cys Val Val
                  35                  40                  45

 Ser Gly Ile Thr Ile Ser Ala Thr Ser Val Tyr Trp Tyr Arg Glu
                  50                  55                  60

 Arg Pro Gly Glu Val Ile Gln Phe Leu Val Ser Ile Ser Tyr Asp
                  65                  70                  75

 Gly Thr Val Arg Lys Glu Ser Gly Ile Pro Ser Gly Lys Phe Glu
                  80                  85                  90

 Val Asp Arg Ile Pro Glu Thr Ser Thr Ser Thr Leu Thr Ile His
                  95                 100                 105

 Asn Val Glu Lys Gln Asp Ile Ala Thr Tyr Tyr Cys Ala Leu Leu
                 110                 115                 120

 Glu Gly Asn Tyr Lys Lys Leu Phe Gly Ser Gly Thr Thr Leu Val
                 125                 130                 135

 Val Thr Asp Lys Gln Leu Asp Ala Asp Val Ser Pro Lys Pro Thr
                 140                 145                 150

 Ile Phe Leu Pro Ser Ile Ala Glu Thr Lys Leu Gln Lys Ala Gly
                 155                 160                 165

 Thr Tyr Leu Cys Leu Leu Glu Lys Phe Phe Pro Asp Val Ile Lys
                 170                 175                 180

 Ile His Trp Gln Glu Lys Lys Ser Asn Thr Ile Leu Gly Ser Gln
                 185                 190                 195

 Glu Gly Asn Thr Met Lys Thr Asn Asp Thr Tyr Met Lys Phe Ser
                 200                 205                 210

 Trp Leu Thr Val Pro Glu Lys Ser Leu Asp Lys Glu His Arg Cys
                 215                 220                 225

 Ile Val Arg His Glu Asn Asn Lys Asn Gly Val Asp Gln Glu Ile
                 230                 235                 240

 Ile Phe Pro Pro Ile Lys Thr Asp Val Ile Thr Met Asp Pro Lys
                 245                 250                 255

 Asp Asn Cys Ser Lys Asp Ala Asn Asp Thr Leu Leu Leu Gln Leu
                 260                 265                 270

 Thr Asn Thr Ser Ala Tyr Tyr Met Tyr Leu Leu Leu Leu Leu Lys
                 275                 280                 285

 Ser Val Val Tyr Phe Ala Ile Ile Thr Cys Cys Leu Leu Arg Arg
                 290                 295                 300

 Thr Ala Phe Cys Cys Asn Gly Glu Lys Ser
                 305                 310

<210> 2104
<211> 2618
<212> DNA
<213> Homo sapien

<400> 2104
 gggagtgtgg cgttctgtga agagttcggt gctaacctcc ctcacgcggc 50

 ggtggctgcc gggaccctag caggtttcag ctggagcggc ggcggcggca 100

 acatggcaga gaccgcggcc ggagtgggcc gcttcaagac caactatgct 150

 gtggagcgca aaattgagcc tttctacaag ggcggaaaag cacagctgga 200

 ccagactggc cagcacctct tctgcgtctg tggcaccaga gtcaacattc 250

 tggaagtggc ctcgggggcc gtgctgcgga gtctggagca ggaggaccag 300

 gaggacatca ctgcctttga cctcagccct gacaacgagg tgctggtgac 350

 agccagtcgg gcattgctgc tggctcagtg ggcctggcaa gagggcagcg 400

 ttacccgcct gtggaaggcg atacacacgg cccccgtggc caccatggcc 450

 ttcgacccca cctccactct gctagccaca ggtggctgtg atggggccgt 500

 gcgcgtctgg gacatcgtgc ggcactacgg gacacaccac ttccgaggct 550

 cgcccggtgt cgtgcaccta gtggccttcc acccggaccc tacacgcctg 600

 ctgctcttct cctcggccac ggatgccgcc atccgcgtgt ggtcactgca 650

 ggaccggtca tgcctggctg tgctgactgc ccactacagc gccgtcacct 700

 cactggcctt cagcgccgac ggccacacca tgctcagctc cggccgtgac 750

 aagatatgta tcatctggga ccttcagagc tgccaggcca cgaggaccgt 800

 gcctgtgttt gagagcgtgg aggctgctgt gctgttgcca gaggagccag 850

 tgtcccagct gggtgtgaag tccccagggc tgtactttct gacagctggc 900

 gaccaaggca ctctgcgcgt gtgggaggca gcttctgggc agtgtgtgta 950

 cacgcaggcc cagccgccgg gccctgggca ggagctgacc cactgcaccc 1000

 tggcacacac cgccggcgtg gtcctcaccg ccaccgccga ccacaacctg 1050

 ttgctctacg aggctcgctc cctgcggctg cagaaacagt tcgctggcta 1100

 cagtgaggag gttttggatg tccggtttct tgggcccgag gactcccacg 1150

 ttgtcgtggc ctccaatagc ccctgcctaa aagtgtttga gctgcagacg 1200

 tcagcctgcc agatcctcca cggccacacg gatatcgtcc tggccctgga 1250

 tgtgttccgg aaggggtggc tctttgccag ctgtgccaag gatcagagcg 1300

 tccgtatctg gagaatgaac aaggctggcc aggtgatgtg cgtggctcag 1350

 ggttccggtc acacacacag tgtgggcacc gtctgctgct ctaggctgaa 1400

 ggagtccttc ctggtgacag gcagccagga ctgcactgtg aagctgtggc 1450

 ctcttcccaa agccttgctg tccaagaaca cagccccaga caacggccct 1500

 atcctcctgc aggcccagac cactcagcgc tgccatgata aggacatcaa 1550

 cagcgtggct attgccccca acgacaagct gctggccaca ggctcacagg 1600

 accgcacggc caagctctgg gccctgccac agtgccagct gctgggtgtc 1650

 ttctcaggcc accggcgtgg cctctggtgc gtccagttct ctcccatgga 1700

 ccaggtgctg gccacggcct cagctgatgg caccatcaag ctctgggcac 1750

 tccaggactt cagctgtctc aagacatttg aggggcacga tgcttctgtg 1800

 ctgaaggtgg cctttgtgag ccgtggcacg cagctgctgt ccagcggttc 1850

 ggatggcctc gtgaagctct ggaccatcaa gaacaacgag tgtgtgcgga 1900

 cgctggatgc ccacgaggac aaggtctggg ggctgcactg cagccggctg 1950

 gacgaccacg ccctcactgg ggccagtgac tcccgagtca tcctctggaa 2000

 ggatgtgacc gaggcggagc aggcagagga gcaggccagg caagaggagc 2050

 aggtggtcag gcagcaagag ctggacaacc tgctgcatga gaagcggtac 2100

 ctgcgggcgc tgggcctggc catctccctg gatcggcccc acaccgtgct 2150

 gactgtcatc caggccatcc ggagggaccc tgaggcctgc gagaagctgg 2200

 aagccaccat gctccgactg cggcgcgacc agaaagaggc cctgctgcgc 2250

 ttctgcgtca cgtggaacac caactcgcgg cactgccacg aggcccaggc 2300

 cgtgctgggt gtgctcttga ggcgagaggc ccccgaggag ctgctggcct 2350

 acgaaggcgt gcgggcagcg cttgaggccc tgctgcccta cactgagcgg 2400

 cactttcagc ggctcagcag gaccctccag gccgccgctt tcttggactt 2450

 cctgtggcac aacatgaagc tccctgtgcc ggccgccgcc cccaccccct 2500

 gggaaaccca taaaggcgca ctgccctagc cggtccggcc tctctccagt 2550

 ccatcctgaa cccctggaaa acccataaag gccgctctcc tggcaaaaaa 2600

 aaaaaaaaaa aaaaaaaa 2618

<210> 2105
<211> 808
<212> PRT
<213> Homo sapien

<400> 2105
 Met Ala Glu Thr Ala Ala Gly Val Gly Arg Phe Lys Thr Asn Tyr
   1               5                  10                  15

 Ala Val Glu Arg Lys Ile Glu Pro Phe Tyr Lys Gly Gly Lys Ala
                  20                  25                  30

 Gln Leu Asp Gln Thr Gly Gln His Leu Phe Cys Val Cys Gly Thr
                  35                  40                  45

 Arg Val Asn Ile Leu Glu Val Ala Ser Gly Ala Val Leu Arg Ser
                  50                  55                  60

 Leu Glu Gln Glu Asp Gln Glu Asp Ile Thr Ala Phe Asp Leu Ser
                  65                  70                  75

 Pro Asp Asn Glu Val Leu Val Thr Ala Ser Arg Ala Leu Leu Leu
                  80                  85                  90

 Ala Gln Trp Ala Trp Gln Glu Gly Ser Val Thr Arg Leu Trp Lys
                  95                 100                 105

 Ala Ile His Thr Ala Pro Val Ala Thr Met Ala Phe Asp Pro Thr
                 110                 115                 120

 Ser Thr Leu Leu Ala Thr Gly Gly Cys Asp Gly Ala Val Arg Val
                 125                 130                 135

 Trp Asp Ile Val Arg His Tyr Gly Thr His His Phe Arg Gly Ser
                 140                 145                 150

 Pro Gly Val Val His Leu Val Ala Phe His Pro Asp Pro Thr Arg
                 155                 160                 165

 Leu Leu Leu Phe Ser Ser Ala Thr Asp Ala Ala Ile Arg Val Trp
                 170                 175                 180

 Ser Leu Gln Asp Arg Ser Cys Leu Ala Val Leu Thr Ala His Tyr
                 185                 190                 195

 Ser Ala Val Thr Ser Leu Ala Phe Ser Ala Asp Gly His Thr Met
                 200                 205                 210

 Leu Ser Ser Gly Arg Asp Lys Ile Cys Ile Ile Trp Asp Leu Gln
                 215                 220                 225

 Ser Cys Gln Ala Thr Arg Thr Val Pro Val Phe Glu Ser Val Glu
                 230                 235                 240

 Ala Ala Val Leu Leu Pro Glu Glu Pro Val Ser Gln Leu Gly Val
                 245                 250                 255

 Lys Ser Pro Gly Leu Tyr Phe Leu Thr Ala Gly Asp Gln Gly Thr
                 260                 265                 270

 Leu Arg Val Trp Glu Ala Ala Ser Gly Gln Cys Val Tyr Thr Gln
                 275                 280                 285

 Ala Gln Pro Pro Gly Pro Gly Gln Glu Leu Thr His Cys Thr Leu
                 290                 295                 300

 Ala His Thr Ala Gly Val Val Leu Thr Ala Thr Ala Asp His Asn
                 305                 310                 315

 Leu Leu Leu Tyr Glu Ala Arg Ser Leu Arg Leu Gln Lys Gln Phe
                 320                 325                 330

 Ala Gly Tyr Ser Glu Glu Val Leu Asp Val Arg Phe Leu Gly Pro
                 335                 340                 345

 Glu Asp Ser His Val Val Val Ala Ser Asn Ser Pro Cys Leu Lys
                 350                 355                 360

 Val Phe Glu Leu Gln Thr Ser Ala Cys Gln Ile Leu His Gly His
                 365                 370                 375

 Thr Asp Ile Val Leu Ala Leu Asp Val Phe Arg Lys Gly Trp Leu
                 380                 385                 390

 Phe Ala Ser Cys Ala Lys Asp Gln Ser Val Arg Ile Trp Arg Met
                 395                 400                 405

 Asn Lys Ala Gly Gln Val Met Cys Val Ala Gln Gly Ser Gly His
                 410                 415                 420

 Thr His Ser Val Gly Thr Val Cys Cys Ser Arg Leu Lys Glu Ser
                 425                 430                 435

 Phe Leu Val Thr Gly Ser Gln Asp Cys Thr Val Lys Leu Trp Pro
                 440                 445                 450

 Leu Pro Lys Ala Leu Leu Ser Lys Asn Thr Ala Pro Asp Asn Gly
                 455                 460                 465

 Pro Ile Leu Leu Gln Ala Gln Thr Thr Gln Arg Cys His Asp Lys
                 470                 475                 480

 Asp Ile Asn Ser Val Ala Ile Ala Pro Asn Asp Lys Leu Leu Ala
                 485                 490                 495

 Thr Gly Ser Gln Asp Arg Thr Ala Lys Leu Trp Ala Leu Pro Gln
                 500                 505                 510

 Cys Gln Leu Leu Gly Val Phe Ser Gly His Arg Arg Gly Leu Trp
                 515                 520                 525

 Cys Val Gln Phe Ser Pro Met Asp Gln Val Leu Ala Thr Ala Ser
                 530                 535                 540

 Ala Asp Gly Thr Ile Lys Leu Trp Ala Leu Gln Asp Phe Ser Cys
                 545                 550                 555

 Leu Lys Thr Phe Glu Gly His Asp Ala Ser Val Leu Lys Val Ala
                 560                 565                 570

 Phe Val Ser Arg Gly Thr Gln Leu Leu Ser Ser Gly Ser Asp Gly
                 575                 580                 585

 Leu Val Lys Leu Trp Thr Ile Lys Asn Asn Glu Cys Val Arg Thr
                 590                 595                 600

 Leu Asp Ala His Glu Asp Lys Val Trp Gly Leu His Cys Ser Arg
                 605                 610                 615

 Leu Asp Asp His Ala Leu Thr Gly Ala Ser Asp Ser Arg Val Ile
                 620                 625                 630

 Leu Trp Lys Asp Val Thr Glu Ala Glu Gln Ala Glu Glu Gln Ala
                 635                 640                 645

 Arg Gln Glu Glu Gln Val Val Arg Gln Gln Glu Leu Asp Asn Leu
                 650                 655                 660

 Leu His Glu Lys Arg Tyr Leu Arg Ala Leu Gly Leu Ala Ile Ser
                 665                 670                 675

 Leu Asp Arg Pro His Thr Val Leu Thr Val Ile Gln Ala Ile Arg
                 680                 685                 690

 Arg Asp Pro Glu Ala Cys Glu Lys Leu Glu Ala Thr Met Leu Arg
                 695                 700                 705

 Leu Arg Arg Asp Gln Lys Glu Ala Leu Leu Arg Phe Cys Val Thr
                 710                 715                 720

 Trp Asn Thr Asn Ser Arg His Cys His Glu Ala Gln Ala Val Leu
                 725                 730                 735

 Gly Val Leu Leu Arg Arg Glu Ala Pro Glu Glu Leu Leu Ala Tyr
                 740                 745                 750

 Glu Gly Val Arg Ala Ala Leu Glu Ala Leu Leu Pro Tyr Thr Glu
                 755                 760                 765

 Arg His Phe Gln Arg Leu Ser Arg Thr Leu Gln Ala Ala Ala Phe
                 770                 775                 780

 Leu Asp Phe Leu Trp His Asn Met Lys Leu Pro Val Pro Ala Ala
                 785                 790                 795

 Ala Pro Thr Pro Trp Glu Thr His Lys Gly Ala Leu Pro
                 800                 805

<210> 2106
<211> 3355
<212> DNA
<213> Homo sapien

<400> 2106
 acatacttct tcctccttcg gaagggctgg taacttgttg agcggacgga 50

 acggcggcgg cggcggcacc atccaggcgg gcaccatggg cacgtccgcg 100

 ctctgggcgc tctggctgct gctcgcgctg tgctgggcgc cccgggagag 150

 cggcgccacc ggaaccggga gaaaagccaa atgtgaaccc tcccaattcc 200

 agtgcacaaa tggtcgctgt attacgctgt tgtggaaatg tgatggggat 250

 gaagactgtg ttgacggcag tgatgaaaag aactgtgtaa agaagacgtg 300

 tgctgaatct gacttcgtgt gcaacaatgg ccagtgtgtt cccagccgat 350

 ggaagtgtga tggagatcct gactgcgaag atggttcaga tgaaagccca 400

 gaacagtgcc atatgagaac atgccgcata catgaaatca gctgtggcgc 450

 ccattctact cagtgtatcc cagtgtcctg gagatgtgat ggtgaaaatg 500

 attgtgacag tggagaagat gaagaaaact gtggcaatat aacatgtagt 550

 cccgacgagt tcacctgctc cagtggccgc tgcatctcca ggaactttgt 600

 ttgcaatggc caggatgact gcagcgatgg cagtgatgag ctggactgtg 650

 ccccgccaac ctgtggcgcc catgagttcc agtgcagcac ctcctcctgc 700

 atccccatca gctgggtatg cgacgatgat gcagactgct ccgaccaatc 750

 tgatgagtcc ctggagcagt gtggccgtca gccagtcata cacaccaagt 800

 gtccagccag cgaaatccag tgcggctctg gcgagtgcat ccataagaag 850

 tggcgatgtg atggggaccc tgactgcaag gatggcagtg atgaggtcaa 900

 ctgtccctct cgaacttgcc gacctgacca atttgaatgt gaggatggca 950

 gctgcatcca tggcagcagg cagtgtaatg gtatccgaga ctgtgtcgat 1000

 ggttccgatg aagtcaactg caaaaatgtc aatcagtgct tgggccctgg 1050

 aaaattcaag tgcagaagtg gagaatgcat agatatcagc aaagtatgta 1100

 accaggagca ggactgcagg gactggagtg atgagcccct gaaagagtgt 1150

 catataaacg aatgcttggt aaataatggt ggatgttctc atatctgcaa 1200

 agacctagtt ataggctacg agtgtgactg tgcagctggg tttgaactga 1250

 tagataggaa aacctgtgga gatattgatg aatgccaaaa tccaggaatc 1300

 tgcagtcaaa tttgtatcaa cttaaaaggc ggttacaagt gtgaatgtag 1350

 tcgtggctat caaatggatc ttgctactgg cgtgtgcaag gcagtaggca 1400

 aagagccaag tctgatcttc actaatcgaa gagacatcag gaagattggc 1450

 ttagagagga aagaatatat ccaactagtt gaacagctaa gaaacactgt 1500

 ggctctcgat gctgacattg ctgcccagaa actattctgg gccgatctaa 1550

 gccaaaaggc tatcttcagt gcctcaattg atgacaaggt tggtagacat 1600

 gttaaaatga tcgacaatgt ctataatcct gcagccattg ctgttgattg 1650

 ggtgtacaag accatctact ggactgatgc ggcttctaag actatttcag 1700

 tagctaccct agatggaacc aagaggaagt tcctgtttaa ctctgacttg 1750

 cgagagcctg cctccatagc tgtggaccca ctgtctggct ttgtttactg 1800

 gtcagactgg ggtgaaccag ctaaaataga aaaagcagga atgaatggat 1850

 tcgatagacg tccactggtg acagcggata tccagtggcc taacggaatt 1900

 acacttgacc ttataaaaag tcgcctctat tggcttgatt ctaagttgca 1950

 catgttatcc agcgtggact tgaatggcca agatcgtagg atagtactaa 2000

 agtctctgga gttcctagct catcctcttg cactaacaat atttgaggat 2050

 cgtgtctact ggatagatgg ggaaaatgaa gcagtctatg gtgccaataa 2100

 attcactgga tcagagctag ccactctagt caacaacctg aatgatgccc 2150

 aagacatcat tgtctatcat gaacttgtac agccatcagg taaaaattgg 2200

 tgtgaagaag acatggagaa tggaggatgt gaatacctat gcctgccagc 2250

 accacaaatt aatgatcact ctccaaaata tacctgttcc tgtcccagtg 2300

 ggtacaatgt agaggaaaat ggccgagact gtcaaagtac tgcaactacw 2350

 gtgacttaca gtgagacaaa agatacgaac acaacagaaa tttcagcaac 2400

 tagtggacta gttcctggag ggatcaatgt gaccacagca gtatcagagg 2450

 tcagtgttcc cccaaaaggg acttctgccg catgggccat tcttcctctc 2500

 ttgctcttag tgatggcagc agtaggtggc tacttgatgt ggcggaattg 2550

 gcaacacaag aacatgaaaa gcatgaactt tgacaatcct gtgtacttga 2600

 aaaccactga agaggacctc tccatagaca ttggtagaca cagtgcttct 2650

 gttggacaca cgtacccagc aatatcagtt gtaagcacag atgatgatct 2700

 agcttgactt ctgtgacaaa tgttgacctt tgaggtctaa acaaataata 2750

 cccccgtcgg aatggtaacc gagccagcag ctgaagtctc tttttcttcc 2800

 tctcggctgg aagaacatca agataccttt gcgtggatca agcttgtgta 2850

 cttgaccgtt tttatattac ttttgtaaat attcttgtcc acattctact 2900

 tcagctttgg atgtggttac cgagtatctg taacccttga atttctagac 2950

 agtattgcca cctctggcca aatatgcact ttccctagaa agccatattc 3000

 cagcagtgaa acttgtgcta tagtgtatac cacctgtaca tacattgtat 3050

 aggccatctg taaatatccc agagaacaat cactattctt aagcactttg 3100

 aaaatatttc tatgtaaatt attgtaaact ttttcaatgg ttgggacaat 3150

 ggcaatagga caaaacgggt tactaagatg aaattgccaa aaaaatttat 3200

 aaactaattt tgtacgtatg aatgatatct ttgacctcaa tggaggtttg 3250

 caaagactga gtgttcaaac tactgtacat ttttttcaag tgctaaaaaa 3300

 attaaaccag cagcttaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3350

 aaaaa 3355

<210> 2107
<211> 873
<212> PRT
<213> Homo sapien

<400> 2107
 Met Gly Thr Ser Ala Leu Trp Ala Leu Trp Leu Leu Leu Ala Leu
   1               5                  10                  15

 Cys Trp Ala Pro Arg Glu Ser Gly Ala Thr Gly Thr Gly Arg Lys
                  20                  25                  30

 Ala Lys Cys Glu Pro Ser Gln Phe Gln Cys Thr Asn Gly Arg Cys
                  35                  40                  45

 Ile Thr Leu Leu Trp Lys Cys Asp Gly Asp Glu Asp Cys Val Asp
                  50                  55                  60

 Gly Ser Asp Glu Lys Asn Cys Val Lys Lys Thr Cys Ala Glu Ser
                  65                  70                  75

 Asp Phe Val Cys Asn Asn Gly Gln Cys Val Pro Ser Arg Trp Lys
                  80                  85                  90

 Cys Asp Gly Asp Pro Asp Cys Glu Asp Gly Ser Asp Glu Ser Pro
                  95                 100                 105

 Glu Gln Cys His Met Arg Thr Cys Arg Ile His Glu Ile Ser Cys
                 110                 115                 120

 Gly Ala His Ser Thr Gln Cys Ile Pro Val Ser Trp Arg Cys Asp
                 125                 130                 135

 Gly Glu Asn Asp Cys Asp Ser Gly Glu Asp Glu Glu Asn Cys Gly
                 140                 145                 150

 Asn Ile Thr Cys Ser Pro Asp Glu Phe Thr Cys Ser Ser Gly Arg
                 155                 160                 165

 Cys Ile Ser Arg Asn Phe Val Cys Asn Gly Gln Asp Asp Cys Ser
                 170                 175                 180

 Asp Gly Ser Asp Glu Leu Asp Cys Ala Pro Pro Thr Cys Gly Ala
                 185                 190                 195

 His Glu Phe Gln Cys Ser Thr Ser Ser Cys Ile Pro Ile Ser Trp
                 200                 205                 210

 Val Cys Asp Asp Asp Ala Asp Cys Ser Asp Gln Ser Asp Glu Ser
                 215                 220                 225

 Leu Glu Gln Cys Gly Arg Gln Pro Val Ile His Thr Lys Cys Pro
                 230                 235                 240

 Ala Ser Glu Ile Gln Cys Gly Ser Gly Glu Cys Ile His Lys Lys
                 245                 250                 255

 Trp Arg Cys Asp Gly Asp Pro Asp Cys Lys Asp Gly Ser Asp Glu
                 260                 265                 270

 Val Asn Cys Pro Ser Arg Thr Cys Arg Pro Asp Gln Phe Glu Cys
                 275                 280                 285

 Glu Asp Gly Ser Cys Ile His Gly Ser Arg Gln Cys Asn Gly Ile
                 290                 295                 300

 Arg Asp Cys Val Asp Gly Ser Asp Glu Val Asn Cys Lys Asn Val
                 305                 310                 315

 Asn Gln Cys Leu Gly Pro Gly Lys Phe Lys Cys Arg Ser Gly Glu
                 320                 325                 330

 Cys Ile Asp Ile Ser Lys Val Cys Asn Gln Glu Gln Asp Cys Arg
                 335                 340                 345

 Asp Trp Ser Asp Glu Pro Leu Lys Glu Cys His Ile Asn Glu Cys
                 350                 355                 360

 Leu Val Asn Asn Gly Gly Cys Ser His Ile Cys Lys Asp Leu Val
                 365                 370                 375

 Ile Gly Tyr Glu Cys Asp Cys Ala Ala Gly Phe Glu Leu Ile Asp
                 380                 385                 390

 Arg Lys Thr Cys Gly Asp Ile Asp Glu Cys Gln Asn Pro Gly Ile
                 395                 400                 405

 Cys Ser Gln Ile Cys Ile Asn Leu Lys Gly Gly Tyr Lys Cys Glu
                 410                 415                 420

 Cys Ser Arg Gly Tyr Gln Met Asp Leu Ala Thr Gly Val Cys Lys
                 425                 430                 435

 Ala Val Gly Lys Glu Pro Ser Leu Ile Phe Thr Asn Arg Arg Asp
                 440                 445                 450

 Ile Arg Lys Ile Gly Leu Glu Arg Lys Glu Tyr Ile Gln Leu Val
                 455                 460                 465

 Glu Gln Leu Arg Asn Thr Val Ala Leu Asp Ala Asp Ile Ala Ala
                 470                 475                 480

 Gln Lys Leu Phe Trp Ala Asp Leu Ser Gln Lys Ala Ile Phe Ser
                 485                 490                 495

 Ala Ser Ile Asp Asp Lys Val Gly Arg His Val Lys Met Ile Asp
                 500                 505                 510

 Asn Val Tyr Asn Pro Ala Ala Ile Ala Val Asp Trp Val Tyr Lys
                 515                 520                 525

 Thr Ile Tyr Trp Thr Asp Ala Ala Ser Lys Thr Ile Ser Val Ala
                 530                 535                 540

 Thr Leu Asp Gly Thr Lys Arg Lys Phe Leu Phe Asn Ser Asp Leu
                 545                 550                 555

 Arg Glu Pro Ala Ser Ile Ala Val Asp Pro Leu Ser Gly Phe Val
                 560                 565                 570

 Tyr Trp Ser Asp Trp Gly Glu Pro Ala Lys Ile Glu Lys Ala Gly
                 575                 580                 585

 Met Asn Gly Phe Asp Arg Arg Pro Leu Val Thr Ala Asp Ile Gln
                 590                 595                 600

 Trp Pro Asn Gly Ile Thr Leu Asp Leu Ile Lys Ser Arg Leu Tyr
                 605                 610                 615

 Trp Leu Asp Ser Lys Leu His Met Leu Ser Ser Val Asp Leu Asn
                 620                 625                 630

 Gly Gln Asp Arg Arg Ile Val Leu Lys Ser Leu Glu Phe Leu Ala
                 635                 640                 645

 His Pro Leu Ala Leu Thr Ile Phe Glu Asp Arg Val Tyr Trp Ile
                 650                 655                 660

 Asp Gly Glu Asn Glu Ala Val Tyr Gly Ala Asn Lys Phe Thr Gly
                 665                 670                 675

 Ser Glu Leu Ala Thr Leu Val Asn Asn Leu Asn Asp Ala Gln Asp
                 680                 685                 690

 Ile Ile Val Tyr His Glu Leu Val Gln Pro Ser Gly Lys Asn Trp
                 695                 700                 705

 Cys Glu Glu Asp Met Glu Asn Gly Gly Cys Glu Tyr Leu Cys Leu
                 710                 715                 720

 Pro Ala Pro Gln Ile Asn Asp His Ser Pro Lys Tyr Thr Cys Ser
                 725                 730                 735

 Cys Pro Ser Gly Tyr Asn Val Glu Glu Asn Gly Arg Asp Cys Gln
                 740                 745                 750

 Ser Thr Ala Thr Thr Val Thr Tyr Ser Glu Thr Lys Asp Thr Asn
                 755                 760                 765

 Thr Thr Glu Ile Ser Ala Thr Ser Gly Leu Val Pro Gly Gly Ile
                 770                 775                 780

 Asn Val Thr Thr Ala Val Ser Glu Val Ser Val Pro Pro Lys Gly
                 785                 790                 795

 Thr Ser Ala Ala Trp Ala Ile Leu Pro Leu Leu Leu Leu Val Met
                 800                 805                 810

 Ala Ala Val Gly Gly Tyr Leu Met Trp Arg Asn Trp Gln His Lys
                 815                 820                 825

 Asn Met Lys Ser Met Asn Phe Asp Asn Pro Val Tyr Leu Lys Thr
                 830                 835                 840

 Thr Glu Glu Asp Leu Ser Ile Asp Ile Gly Arg His Ser Ala Ser
                 845                 850                 855

 Val Gly His Thr Tyr Pro Ala Ile Ser Val Val Ser Thr Asp Asp
                 860                 865                 870

 Asp Leu Ala


<210> 2108
<211> 929
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 58
<223> Unknown base

<400> 2108
 ttttctgagg tacatcagat ccatcaggtc cgagctgtgt tgactaccac 50

 tacttttncc ttcgtctcaa ttatgtcttg gaaaaaggct ttgcggatcc 100

 ccggaggcct tcgggcagca actgttacct tgatgctggc gatgctgagc 150

 accccaatgg ctgagggcag agactctccc gaggatttcg tgtaccagtt 200

 taaggccatg tgctacatca ccaacgggac ggagcgcttg cgttatgtga 250

 ccagatacat ctataaccga gaggagtacg cacgcttcga cagcgacgtg 300

 gaggtgtacc gggcggtgac gccgctgggg ccgcctgacg ccgagtactg 350

 gaacagccag aaggaagtcc tggagaggac ccgggcggag ttggacacgg 400

 tgtgcagaca caactaccag ttggagctcc gcacgacctt gcagcggcga 450

 gtggagccca cagtgaccat ctccccatcc aggacagagg ccctcaacca 500

 ccacaacctg ctggtctgct cagtgacaga tttctatcca gcccagatca 550

 aagtccggtg gtttcggaat gaccaggagg agacaaccgg cgttgtgtcc 600

 acccccctta ttaggaacgg tgactggacc ttccagatcc tggtgatgct 650

 ggaaatgact ccccagcatg gagacgtcta cacctgccac gtggagcacc 700

 ccagcctcca gaaccccatc accgtggagt ggcgggctca gtctgaatct 750

 gcccagagca agatgctgag tggcattgga ggcttcgtgc tggggctcat 800

 cttcctcggg ctgggcctta ttatccatca caggagtcag aaagggctcc 850

 tgcactgact cctgagacta ttttaactgg gattggttat cacttttctg 900

 taacgcctgc ttgtccctgc ccagaattc 929

<210> 2109
<211> 261
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 58
<223> Unknown amino acid

<400> 2109
 Met Ser Trp Lys Lys Ala Leu Arg Ile Pro Gly Gly Leu Arg Ala
   1               5                  10                  15

 Ala Thr Val Thr Leu Met Leu Ala Met Leu Ser Thr Pro Met Ala
                  20                  25                  30

 Glu Gly Arg Asp Ser Pro Glu Asp Phe Val Tyr Gln Phe Lys Ala
                  35                  40                  45

 Met Cys Tyr Ile Thr Asn Gly Thr Glu Arg Leu Arg Tyr Val Thr
                  50                  55                  60

 Arg Tyr Ile Tyr Asn Arg Glu Glu Tyr Ala Arg Phe Asp Ser Asp
                  65                  70                  75

 Val Glu Val Tyr Arg Ala Val Thr Pro Leu Gly Pro Pro Asp Ala
                  80                  85                  90

 Glu Tyr Trp Asn Ser Gln Lys Glu Val Leu Glu Arg Thr Arg Ala
                  95                 100                 105

 Glu Leu Asp Thr Val Cys Arg His Asn Tyr Gln Leu Glu Leu Arg
                 110                 115                 120

 Thr Thr Leu Gln Arg Arg Val Glu Pro Thr Val Thr Ile Ser Pro
                 125                 130                 135

 Ser Arg Thr Glu Ala Leu Asn His His Asn Leu Leu Val Cys Ser
                 140                 145                 150

 Val Thr Asp Phe Tyr Pro Ala Gln Ile Lys Val Arg Trp Phe Arg
                 155                 160                 165

 Asn Asp Gln Glu Glu Thr Thr Gly Val Val Ser Thr Pro Leu Ile
                 170                 175                 180

 Arg Asn Gly Asp Trp Thr Phe Gln Ile Leu Val Met Leu Glu Met
                 185                 190                 195

 Thr Pro Gln His Gly Asp Val Tyr Thr Cys His Val Glu His Pro
                 200                 205                 210

 Ser Leu Gln Asn Pro Ile Thr Val Glu Trp Arg Ala Gln Ser Glu
                 215                 220                 225

 Ser Ala Gln Ser Lys Met Leu Ser Gly Ile Gly Gly Phe Val Leu
                 230                 235                 240

 Gly Leu Ile Phe Leu Gly Leu Gly Leu Ile Ile His His Arg Ser
                 245                 250                 255

 Gln Lys Gly Leu Leu His
                 260

<210> 2110
<211> 2776
<212> DNA
<213> Homo sapien

<400> 2110
 gcggccgcgt cgaccggagg tgcctgttta cccgcgccgg actcaccgcc 50

 gccgccgccg cgggatccga gtgcgggcgc gggcgcgggc gctcccggcg 100

 agccacggtg gtgctggcta gagtgtttac gtttggaccc aagcttaact 150

 tttccaatgt ggaatcctgg gccttcattg gttccgatgt cataggaatc 200

 tacgctagag ggcttcctgt gtgccgggca ctgtggtttt tggaagaagc 250

 tgaccgcctg aaaagaaatt ataaaacatg aaaatcgctt tgaggtgacc 300

 aagtccagag gcccctaact cctcccaagc tggatctggg gtgtaagaac 350

 tgtgacttca gatcatccaa tggcagacca gagaatggac atttcttcaa 400

 ccatcagtga tttcatgtcc ccgggcccca ccgacctgct ttccagctct 450

 cttggtacca gtggtgtgga ttgcaaccgc aaacggaaag gcagctccac 500

 tgactaccaa gaaagcatgg acacagacaa agatgaccct catggaaggt 550

 tagaatatac agaacaccaa ggaaggataa aaaatgcaag ggaagctcac 600

 agtcagattg aaaagcggcg tcgggataaa atgaacagtt ttatagatga 650

 attggcttct ttggtaccaa catgcaacgc aatgtccagg aaattagata 700

 aacttactgt gctaaggatg gctgttcagc acatgaaaac attaagaggt 750

 gccaccaatc catacacaga agcaaactac aaaccaactt ttctatcaga 800

 cgatgaattg aaacacctca ttctcagggc agcagatgga tttttgtttg 850

 tcgtaggatg tgaccgaggg aagatactct ttgtctcaga gtctgtcttc 900

 aagatcctca actacagcca gaatgatctg attggtcaga gtttgtttga 950

 ctacctgcat cctaaagata ttgccaaagt caaggagcag ctctcctcct 1000

 ctgacaccgc accccgggag cggctcatag atgcaaaaac tggacttcca 1050

 gttaaaacag atataacccc tgggccatct cgattatgtt ctggagcacg 1100

 acgttctttc ttctgtagga tgaagtgtaa caggccttca gtaaaggttg 1150

 aagacaagga cttcccctct acctgctcaa agaaaaaagc agatcgaaaa 1200

 agcttctgca caatccacag cacaggctat ttgaaaagct ggccacccac 1250

 aaagatgggg ctggatgaag acaacgaacc agacaatgag gggtgtaacc 1300

 tcagctgcct cgtcgcaatt ggacgactgc attctcatgt agttccacaa 1350

 ccagtgaacg gggaaatcag ggtgaaatct atggaatatg tttctcggca 1400

 cgcgatagat ggaaagtttg tttttgtaga ccagagggca acagctattt 1450

 tggcatattt accacaagaa cttctaggca catcgtgtta tgaatatttt 1500

 caccaagatg acataggaca tcttgcagaa tgtcataggc aagttttaca 1550

 gacgagagaa aaaattacaa ctaattgcta taaatttaaa atcaaagatg 1600

 gttcttttat cacactacgg agtcgatggt tcagtttcat gaacccttgg 1650

 accaaggaag tagaatatat tgtctcaact aacactgttg ttttagccaa 1700

 cgtcctggaa ggcggggacc caaccttccc acagctcaca gcatcccccc 1750

 acagcatgga cagcatgctg ccctctggag aaggtggccc aaagaggacc 1800

 caccccactg ttccagggat tccaggggga acccgggctg gggcaggaaa 1850

 aataggccga atgattgctg aggaaatcat ggaaatccac aggataagag 1900

 ggtcatcgcc ttctagctgt ggctccagcc cattgaacat cacgagtacg 1950

 cctccccctg atgcctcttc tccaggaggc aagaagattt taaatggagg 2000

 gactccagac attccttcca gtggcctact atcaggccag gctcaggaga 2050

 acccaggtta tccatattct gatagttctt ctattcttgg tgagaacccc 2100

 cacataggta tagacatgat tgacaacgac caaggatcaa gtagtcccag 2150

 taatgatgag gcagcaatgg ctgtcatcat gagcctcttg gaagcagatg 2200

 ctggactggg tggccctgtt gactttagtg acttgccatg gccgctgtaa 2250

 acactacatg ttgctttggc aacagctata gtatcaaagt gcattactgg 2300

 tggagtttta cagtctgtga agcttactgg ataaggagag aatagctttt 2350

 atgtactgac ttcataaaag ccatctcaga gccattgata caagtcaatc 2400

 ttactatatg taacttcaga caaagtggaa ctaagcctgc tccagtgttt 2450

 cctcatcatt gattattggg ctagctgtgg atagcttgca ttaattgtat 2500

 attttggatt ctgtttgtgt tgaatttttt aatcattgtg cacagaagca 2550

 tcattggtag cttttatatg caaatggtca tttcagatgt atggtgtttt 2600

 tacactacaa agaagtcccc catgtggata tttcttatac taattgtatc 2650

 ataaagccgt ttattcttcc ttgtaagaat cctttactat aaatatgggt 2700

 taaagtataa tgtactagac agttaaatat ttttaataaa tgtttccctt 2750

 gttctataaa aaaaaaaaaa aaaaaa 2776

<210> 2111
<211> 626
<212> PRT
<213> Homo sapien

<400> 2111
 Met Ala Asp Gln Arg Met Asp Ile Ser Ser Thr Ile Ser Asp Phe
   1               5                  10                  15

 Met Ser Pro Gly Pro Thr Asp Leu Leu Ser Ser Ser Leu Gly Thr
                  20                  25                  30

 Ser Gly Val Asp Cys Asn Arg Lys Arg Lys Gly Ser Ser Thr Asp
                  35                  40                  45

 Tyr Gln Glu Ser Met Asp Thr Asp Lys Asp Asp Pro His Gly Arg
                  50                  55                  60

 Leu Glu Tyr Thr Glu His Gln Gly Arg Ile Lys Asn Ala Arg Glu
                  65                  70                  75

 Ala His Ser Gln Ile Glu Lys Arg Arg Arg Asp Lys Met Asn Ser
                  80                  85                  90

 Phe Ile Asp Glu Leu Ala Ser Leu Val Pro Thr Cys Asn Ala Met
                  95                 100                 105

 Ser Arg Lys Leu Asp Lys Leu Thr Val Leu Arg Met Ala Val Gln
                 110                 115                 120

 His Met Lys Thr Leu Arg Gly Ala Thr Asn Pro Tyr Thr Glu Ala
                 125                 130                 135

 Asn Tyr Lys Pro Thr Phe Leu Ser Asp Asp Glu Leu Lys His Leu
                 140                 145                 150

 Ile Leu Arg Ala Ala Asp Gly Phe Leu Phe Val Val Gly Cys Asp
                 155                 160                 165

 Arg Gly Lys Ile Leu Phe Val Ser Glu Ser Val Phe Lys Ile Leu
                 170                 175                 180

 Asn Tyr Ser Gln Asn Asp Leu Ile Gly Gln Ser Leu Phe Asp Tyr
                 185                 190                 195

 Leu His Pro Lys Asp Ile Ala Lys Val Lys Glu Gln Leu Ser Ser
                 200                 205                 210

 Ser Asp Thr Ala Pro Arg Glu Arg Leu Ile Asp Ala Lys Thr Gly
                 215                 220                 225

 Leu Pro Val Lys Thr Asp Ile Thr Pro Gly Pro Ser Arg Leu Cys
                 230                 235                 240

 Ser Gly Ala Arg Arg Ser Phe Phe Cys Arg Met Lys Cys Asn Arg
                 245                 250                 255

 Pro Ser Val Lys Val Glu Asp Lys Asp Phe Pro Ser Thr Cys Ser
                 260                 265                 270

 Lys Lys Lys Ala Asp Arg Lys Ser Phe Cys Thr Ile His Ser Thr
                 275                 280                 285

 Gly Tyr Leu Lys Ser Trp Pro Pro Thr Lys Met Gly Leu Asp Glu
                 290                 295                 300

 Asp Asn Glu Pro Asp Asn Glu Gly Cys Asn Leu Ser Cys Leu Val
                 305                 310                 315

 Ala Ile Gly Arg Leu His Ser His Val Val Pro Gln Pro Val Asn
                 320                 325                 330

 Gly Glu Ile Arg Val Lys Ser Met Glu Tyr Val Ser Arg His Ala
                 335                 340                 345

 Ile Asp Gly Lys Phe Val Phe Val Asp Gln Arg Ala Thr Ala Ile
                 350                 355                 360

 Leu Ala Tyr Leu Pro Gln Glu Leu Leu Gly Thr Ser Cys Tyr Glu
                 365                 370                 375

 Tyr Phe His Gln Asp Asp Ile Gly His Leu Ala Glu Cys His Arg
                 380                 385                 390

 Gln Val Leu Gln Thr Arg Glu Lys Ile Thr Thr Asn Cys Tyr Lys
                 395                 400                 405

 Phe Lys Ile Lys Asp Gly Ser Phe Ile Thr Leu Arg Ser Arg Trp
                 410                 415                 420

 Phe Ser Phe Met Asn Pro Trp Thr Lys Glu Val Glu Tyr Ile Val
                 425                 430                 435

 Ser Thr Asn Thr Val Val Leu Ala Asn Val Leu Glu Gly Gly Asp
                 440                 445                 450

 Pro Thr Phe Pro Gln Leu Thr Ala Ser Pro His Ser Met Asp Ser
                 455                 460                 465

 Met Leu Pro Ser Gly Glu Gly Gly Pro Lys Arg Thr His Pro Thr
                 470                 475                 480

 Val Pro Gly Ile Pro Gly Gly Thr Arg Ala Gly Ala Gly Lys Ile
                 485                 490                 495

 Gly Arg Met Ile Ala Glu Glu Ile Met Glu Ile His Arg Ile Arg
                 500                 505                 510

 Gly Ser Ser Pro Ser Ser Cys Gly Ser Ser Pro Leu Asn Ile Thr
                 515                 520                 525

 Ser Thr Pro Pro Pro Asp Ala Ser Ser Pro Gly Gly Lys Lys Ile
                 530                 535                 540

 Leu Asn Gly Gly Thr Pro Asp Ile Pro Ser Ser Gly Leu Leu Ser
                 545                 550                 555

 Gly Gln Ala Gln Glu Asn Pro Gly Tyr Pro Tyr Ser Asp Ser Ser
                 560                 565                 570

 Ser Ile Leu Gly Glu Asn Pro His Ile Gly Ile Asp Met Ile Asp
                 575                 580                 585

 Asn Asp Gln Gly Ser Ser Ser Pro Ser Asn Asp Glu Ala Ala Met
                 590                 595                 600

 Ala Val Ile Met Ser Leu Leu Glu Ala Asp Ala Gly Leu Gly Gly
                 605                 610                 615

 Pro Val Asp Phe Ser Asp Leu Pro Trp Pro Leu
                 620                 625

<210> 2112
<211> 1284
<212> DNA
<213> Homo sapien

<400> 2112
 ggctccttcg ggaaacccag ccccgtcacc gggctccgag cggctcgcag 50

 gcgagcgaca gcggcctcag ccccggcagc gcccagcggc ggctgcggaa 100

 agcggaggga gtccgacgcg ggcgcgggcg gggagcgtgc gtccgttcgc 150

 acaggcagcg ggaggagggg cggcgcgaac catggccggg gacagcgagc 200

 agaccctgca gaaccaccag cagcccaacg gcggcgagcc cttccttata 250

 ggcgtcagcg ggggaacagc tagcggcaag tcttccgtgt gtgctaagat 300

 cgtgcagctc ctggggcaga atgaggtgga ctatcgccag aagcaggtgg 350

 tcatcctgag ccaggatagc ttctaccgtg tccttacctc ggagcagaag 400

 gccaaagccc tgaagggcca gttcaacttt gaccacccgg atgcctttga 450

 caatgaactc attctcaaaa cactcaaaga aatcactgaa gggaaaacag 500

 tccagatccc cgtgtatgac tttgtctccc attcccggaa ggaggagaca 550

 gttactgtct atcccgcaga cgtggtgctc tttgaaggga tcctggcctt 600

 ctactcccag gaggtacgag acctgttcca gatgaagctt tttgtggata 650

 cagatgcgga cacccggctc tcacgcagag tattaaggga catcagcgag 700

 agaggcaggg atcttgagca gattttatct cagtacatta cgttcgtcaa 750

 gcctgccttt gaggaattct gcttgccaac aaagaagtat gctgatgtga 800

 tcatccctag aggtgcagat aatctggtgg ccatcaacct catcgtgcag 850

 cacatccagg acatcctgaa tggagggccc tccaaacggc agaccaatgg 900

 ctgtctcaac ggctacaccc cttcacgcaa gaggcaggca tcggagtcca 950

 gcagcaggcc gcattgaccc gtctccatcg gaccccagcc cctatctcca 1000

 agagacagag gaggggtcag gaggcactgc tcatctgtac atactgtttc 1050

 ctatgacatt actgtattta agaaaacacc atggagatga aatgcctttg 1100

 attttttttt tctttttgta ctttggaacg acaaaatgaa acagaacttg 1150

 accctgagct taaataacaa aactgtgcca actactactg gtgatgccta 1200

 attatgaatc caacgtgtaa ccagttataa atacatatat atataaaaaa 1250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1284

<210> 2113
<211> 261
<212> PRT
<213> Homo sapien

<400> 2113
 Met Ala Gly Asp Ser Glu Gln Thr Leu Gln Asn His Gln Gln Pro
   1               5                  10                  15

 Asn Gly Gly Glu Pro Phe Leu Ile Gly Val Ser Gly Gly Thr Ala
                  20                  25                  30

 Ser Gly Lys Ser Ser Val Cys Ala Lys Ile Val Gln Leu Leu Gly
                  35                  40                  45

 Gln Asn Glu Val Asp Tyr Arg Gln Lys Gln Val Val Ile Leu Ser
                  50                  55                  60

 Gln Asp Ser Phe Tyr Arg Val Leu Thr Ser Glu Gln Lys Ala Lys
                  65                  70                  75

 Ala Leu Lys Gly Gln Phe Asn Phe Asp His Pro Asp Ala Phe Asp
                  80                  85                  90

 Asn Glu Leu Ile Leu Lys Thr Leu Lys Glu Ile Thr Glu Gly Lys
                  95                 100                 105

 Thr Val Gln Ile Pro Val Tyr Asp Phe Val Ser His Ser Arg Lys
                 110                 115                 120

 Glu Glu Thr Val Thr Val Tyr Pro Ala Asp Val Val Leu Phe Glu
                 125                 130                 135

 Gly Ile Leu Ala Phe Tyr Ser Gln Glu Val Arg Asp Leu Phe Gln
                 140                 145                 150

 Met Lys Leu Phe Val Asp Thr Asp Ala Asp Thr Arg Leu Ser Arg
                 155                 160                 165

 Arg Val Leu Arg Asp Ile Ser Glu Arg Gly Arg Asp Leu Glu Gln
                 170                 175                 180

 Ile Leu Ser Gln Tyr Ile Thr Phe Val Lys Pro Ala Phe Glu Glu
                 185                 190                 195

 Phe Cys Leu Pro Thr Lys Lys Tyr Ala Asp Val Ile Ile Pro Arg
                 200                 205                 210

 Gly Ala Asp Asn Leu Val Ala Ile Asn Leu Ile Val Gln His Ile
                 215                 220                 225

 Gln Asp Ile Leu Asn Gly Gly Pro Ser Lys Arg Gln Thr Asn Gly
                 230                 235                 240

 Cys Leu Asn Gly Tyr Thr Pro Ser Arg Lys Arg Gln Ala Ser Glu
                 245                 250                 255

 Ser Ser Ser Arg Pro His
                 260

<210> 2114
<211> 5471
<212> DNA
<213> Homo sapien

<400> 2114
 ccggggtccc ctttcaccca agtgagccag ctcaggctgt ctgcaaagcc 50

 ggaggtgcgg gcagctccgg gcattgcatt ggtgcggagg cttttatatg 100

 ccagagaacc ctgagtgtgc ccctgacatg acaaggagcc gtcgtcgtta 150

 ggactaccga ccagactccc ggaaatcatg ttggtaggat cccagtcttt 200

 ttcgcctgga gggcccaatg ggatcattag aagccagtcc tttgcgggtt 250

 tcagcggcct ccaggaaagg cgatccaggt gtaactcctt cattgaaaat 300

 tcctccgctc tcaagaagcc tcaggccaaa ctgaagaaaa tgcacaattt 350

 aggccacaaa aacaacaatc cccccaaaga gcctcagcct aaaagggtgg 400

 aagaagtcta cagggccttg aaaaatggac ttgatgaata tctggaggtt 450

 caccagacgg agctggacaa gttgacagct cagttaaaag atatgaaaag 500

 aaactctcgc ctgggtgtac tgtatgacct agacaagcaa attaaaacaa 550

 ttgaaagata catgagacgc ctggagtttc atataagtaa ggtagatgaa 600

 ctctatgaag cttattgtat ccagcgacgc ctccaggatg gtgccagcaa 650

 aatgaagcaa gccttcgcaa catcccctgc cagcaaagct gcccgggaga 700

 gtctgacaga gatcaatcgg agcttcaagg agtacacaga gaatatgtgc 750

 accattgaag tggagctaga gaatctgctg ggagaattct ccatcaagat 800

 gaaaggtctg gctggctttg cacgcctctg tcctggagat caatatgaaa 850

 ttttcatgaa gtatggccgg cagcggtgga aactgaaagg caaaatagaa 900

 gtaaatggca agcagagctg ggatggagaa gaaacagttt ttctgcccct 950

 gatagttggg ttcatctcca tcaaggtcac ggagctcaaa gggctagcaa 1000

 ctcacatcct ggtaggtagc gtgacctgtg agaccaaaga gctgtttgca 1050

 gcccgacctc aggtagtggc tgtcgacatc aatgaccttg gtaccatcaa 1100

 actgaacctg gaaatcacct ggtatccatt tgacatggag gacatgaccg 1150

 catcctcagg cgctgggaac aaggcagcag cccttcagag gagaatgtcc 1200

 atgtacagcc agggtacccc ggaaacgccc accttcaaag accactcctt 1250

 ctttaggtgg ctgcatcctt ccccagacaa gcccaggcgg ctgtctgtct 1300

 tgagtgcctt gcaagacact ttctttgcca agctgcaccg cagccgctcc 1350

 ttcagtgacc tgccctccct caggccgagt cccaaggccg tgctagagct 1400

 ctattcaaat ctacctgatg acatctttga aaatggaaag gcagccgagg 1450

 agaaaatgcc actgtcgctc agcttcagtg acctgcccaa cggggactgc 1500

 gccctcacct cccactcaac aggctcccct tccaactcaa caaatccaga 1550

 aattaccatc acccctgcgg agtttaacct cagcagcttg gcctcccaga 1600

 atgagggtat ggatgacacc agctcagcat cttccaggaa ctccctggga 1650

 gaaggccaag agccaaagtc acacctgaag gaggaagacc cagaggagcc 1700

 cagaaaacct gcctcggccc catctgaggc ttgccgccga cagtcctcag 1750

 gtgctggggc tgagcacctg ttccttgaga atgatgttgc agaagcactt 1800

 ctgcaagagt ctgaggaggc ctctgagctc aagcctgtgg aactggacac 1850

 ttcggaagga aacatcacaa agcagctggt caagaggctc acatctgcag 1900

 aggtgccaat ggccacagac aggctgctct ctgagggttc tgttggtgga 1950

 gaatctgaag gctgcagatc ctttctagat ggaagcttag aggatgcttt 2000

 taatgggctt ttacttgcat tagaaccaca taaagagcag tataaagagt 2050

 ttcaggatct gaaccaagaa gtcatgaatt tggatgatat tctaaaatgc 2100

 aagccagcag taagccgcag caggtcttcc agtttaagtc tcacagttga 2150

 aagtgcttta gaaagctttg atttcctgaa cacctctgat tttgacgagg 2200

 aggaggatgg tgatgaggtt tgtaatgttg gcggaggtgc tgactcagta 2250

 ttttcagaca ctgagactga gaaacacagt tacaggtcgg ttcacccaga 2300

 agccaggggg catctcagtg aagcgctcac tgaagacaca ggagttggga 2350

 ccagtgtggc aggaagtcct ctcccactga ccacaggcaa cgagagcctg 2400

 gacatcacca tcgtcaggca cctccagtac tgcacccaac tcgtgcagca 2450

 aattgttttc tcaagcaaaa ccccatttgt ggcaagaagt ctcttagaga 2500

 agctttctag gcagatccaa gtgatggaga aactcgcagc tgtcagtgat 2550

 gagaacatag gaaatatcag ttctgttgtg gaagccatac cagaatttca 2600

 caaaaagctg tctttgctgt cattctggac caagtgctgc agccctgttg 2650

 gtgtctacca cagcccagcg gacagagtga tgaagcagct ggaggccagc 2700

 tttgccagaa ctgtcaacaa agaatatcca ggacttgcag acccagtgtt 2750

 tcgaaccctg gtgtcccaaa ttctggacca ggctgagcct ctgctttcct 2800

 ccagcctgtc ctcggaagtc gtcactgttt tccagtatta cagttacttc 2850

 accagccacg gcgtcagtga cctggagagt tacctgagcc agctggccag 2900

 gcaagtttcc atggttcaga ctctgcaatc actaagagat gaaaaactgc 2950

 tacaaaccat gagtgacctt gctcccagca acctcctggc ccagcaggaa 3000

 gtactcagga ctctggctct gctattaacc agagaggaca acgaagttag 3050

 cgaggctgtg acgctttact tggcagcagc ctccaaaaat cagcatttca 3100

 gggaaaaggc cttgctctat tactgtgaag cactaacaaa gacaaacctc 3150

 cagctccaga aagcagcttg cctggctctg aaaatccttg aggctactga 3200

 aagcattaaa atgctggtga cattgtgtca atctgatact gaagaaatca 3250

 gaaatgtggc ctcagaaacc ctcttgtctc tgggagaaga tgggcggctg 3300

 gcatatgaac aattggacaa atttcctcga gactgtgtta aagtcggagg 3350

 tcgtcatgga actgaagttg ccacagcctt ttaattacag attaactgcc 3400

 taacagctgt cttaatatct ggcccttttc atcaggatgg tgctgtggtt 3450

 tgggctggaa attgtttaga gcctgagaga cacgacaact gaaataaaaa 3500

 tgtaggccag gtgcagtggc tcatgcctgt aatcccagta ctttgggagg 3550

 ccaacgcagg agaattgctt aagcccagga ggttcaagac caacctgggc 3600

 aacatagcaa ggccctgtct ctacaaaaaa aatagtttaa ttagtcgggc 3650

 gtggtggcat gcacctgtag tcccagctac ttgggaggct aaggtgggag 3700

 gattgcttga gcccagaaga ttcaggctgc agtgagccat aattgcccca 3750

 ctgcactcca gactgggtga cagagcaaaa ccctgtctca aaaaacaaaa 3800

 caacaacaac aactaaaaaa acatgttata gaaagaattc agagtctcgt 3850

 ttcacagtac ctatctactt ttcctttggc caatatagaa tagggctatg 3900

 gtataattca aatagattac atcgtcgatt gtgtctaata atactcagtg 3950

 aaagagtcca tcttatctta atatgtatga aatttaaaaa tagccatctt 4000

 tgtacttttt tgcaagtttc tctataagct tgaaatagtc atgtgatact 4050

 tcgacaaaca tcatatgcct tgcagttttt ctcggtcgtg ttctcagggt 4100

 tgagtagtcc ccttagctac ctaactttac tttcaataca aagcacaaaa 4150

 aagaatactt caaataaaag tttgcctgca gaacctggca aaatgaccca 4200

 ttatgagagt ttagatgttt taattttatg tgctcccagc tactctggag 4250

 tctgaggtgg gaggatcact tgaggcagag gttgcagtaa gctgagatta 4300

 cactactgca ctccagccca tgtgacagag gaatgagagc cagtctcaaa 4350

 aaaaaaaaac aaaaaactcc cataatttat tttgtttctt ttccccatcc 4400

 tgaaaattcc caaatcatgt ttccattatg gaaaaatgat aagtaaatga 4450

 ctaagaacta cattaagatt atgcctatac acttaaacaa aaaactcaaa 4500

 gcttatgctt ttttttttta attaatgaga gctatttttt atgatattct 4550

 taccataggg gtgttttgct gctaagacaa atcaaaacca aaagctgtag 4600

 attcacaaac ctgtgatgct ctttgaggtg gaggaaccta gaagtcagag 4650

 aaatcctaat ggagtaggag tggaggaaca tttaaagtgg tccctccttc 4700

 tgtaaaaatg accgtgggat tagaaagaag gacatcctga ggggtggtta 4750

 ctgcccccag ggaaatcact cactggtagg attccctggc caaatagttc 4800

 aaacatcagg tcccattatt gcttcagtat cagagatgca agttcattaa 4850

 gcaaagtaca agaccattca gtagctctta ttaaaatatc ttttcttcct 4900

 ctaaagagtg tacaaggtgg ggtatgccaa ggtatcaaaa caatatatgt 4950

 gagtgtaatt taaactgtgg aatatcaact gtactatgga cgtgtttgta 5000

 tcatttagat gtcattttaa atatttacat tttagcaaga cttttaaaaa 5050

 ggactcattt catttcaaag tgcaaattgt ttgccaggct tctggcaaat 5100

 ggttctttca actgtgaact tatagtgtac atatctgtat atttataaat 5150

 attatatata ttcatacatc cttcagttta aaggtacatt gtacagtctg 5200

 tagttaggag gtatagccta tagcttatgt taaatggttg aaatggttct 5250

 ttttatagaa agtcaaacac agatgttaca ggattttgtg tttggtttgt 5300

 cattttttta ttttttattt tgactattgc atgagtaatt aattccagat 5350

 cttttgtatt cacttctgta ttttatgttt ggttgagggg tgcttttagt 5400

 tgtgtggcat ttgtattcat tgatctttca gtcatgtaag ttaaaataaa 5450

 aattattttt gaattactag c 5471

<210> 2115
<211> 1068
<212> PRT
<213> Homo sapien

<400> 2115
 Met Leu Val Gly Ser Gln Ser Phe Ser Pro Gly Gly Pro Asn Gly
   1               5                  10                  15

 Ile Ile Arg Ser Gln Ser Phe Ala Gly Phe Ser Gly Leu Gln Glu
                  20                  25                  30

 Arg Arg Ser Arg Cys Asn Ser Phe Ile Glu Asn Ser Ser Ala Leu
                  35                  40                  45

 Lys Lys Pro Gln Ala Lys Leu Lys Lys Met His Asn Leu Gly His
                  50                  55                  60

 Lys Asn Asn Asn Pro Pro Lys Glu Pro Gln Pro Lys Arg Val Glu
                  65                  70                  75

 Glu Val Tyr Arg Ala Leu Lys Asn Gly Leu Asp Glu Tyr Leu Glu
                  80                  85                  90

 Val His Gln Thr Glu Leu Asp Lys Leu Thr Ala Gln Leu Lys Asp
                  95                 100                 105

 Met Lys Arg Asn Ser Arg Leu Gly Val Leu Tyr Asp Leu Asp Lys
                 110                 115                 120

 Gln Ile Lys Thr Ile Glu Arg Tyr Met Arg Arg Leu Glu Phe His
                 125                 130                 135

 Ile Ser Lys Val Asp Glu Leu Tyr Glu Ala Tyr Cys Ile Gln Arg
                 140                 145                 150

 Arg Leu Gln Asp Gly Ala Ser Lys Met Lys Gln Ala Phe Ala Thr
                 155                 160                 165

 Ser Pro Ala Ser Lys Ala Ala Arg Glu Ser Leu Thr Glu Ile Asn
                 170                 175                 180

 Arg Ser Phe Lys Glu Tyr Thr Glu Asn Met Cys Thr Ile Glu Val
                 185                 190                 195

 Glu Leu Glu Asn Leu Leu Gly Glu Phe Ser Ile Lys Met Lys Gly
                 200                 205                 210

 Leu Ala Gly Phe Ala Arg Leu Cys Pro Gly Asp Gln Tyr Glu Ile
                 215                 220                 225

 Phe Met Lys Tyr Gly Arg Gln Arg Trp Lys Leu Lys Gly Lys Ile
                 230                 235                 240

 Glu Val Asn Gly Lys Gln Ser Trp Asp Gly Glu Glu Thr Val Phe
                 245                 250                 255

 Leu Pro Leu Ile Val Gly Phe Ile Ser Ile Lys Val Thr Glu Leu
                 260                 265                 270

 Lys Gly Leu Ala Thr His Ile Leu Val Gly Ser Val Thr Cys Glu
                 275                 280                 285

 Thr Lys Glu Leu Phe Ala Ala Arg Pro Gln Val Val Ala Val Asp
                 290                 295                 300

 Ile Asn Asp Leu Gly Thr Ile Lys Leu Asn Leu Glu Ile Thr Trp
                 305                 310                 315

 Tyr Pro Phe Asp Met Glu Asp Met Thr Ala Ser Ser Gly Ala Gly
                 320                 325                 330

 Asn Lys Ala Ala Ala Leu Gln Arg Arg Met Ser Met Tyr Ser Gln
                 335                 340                 345

 Gly Thr Pro Glu Thr Pro Thr Phe Lys Asp His Ser Phe Phe Arg
                 350                 355                 360

 Trp Leu His Pro Ser Pro Asp Lys Pro Arg Arg Leu Ser Val Leu
                 365                 370                 375

 Ser Ala Leu Gln Asp Thr Phe Phe Ala Lys Leu His Arg Ser Arg
                 380                 385                 390

 Ser Phe Ser Asp Leu Pro Ser Leu Arg Pro Ser Pro Lys Ala Val
                 395                 400                 405

 Leu Glu Leu Tyr Ser Asn Leu Pro Asp Asp Ile Phe Glu Asn Gly
                 410                 415                 420

 Lys Ala Ala Glu Glu Lys Met Pro Leu Ser Leu Ser Phe Ser Asp
                 425                 430                 435

 Leu Pro Asn Gly Asp Cys Ala Leu Thr Ser His Ser Thr Gly Ser
                 440                 445                 450

 Pro Ser Asn Ser Thr Asn Pro Glu Ile Thr Ile Thr Pro Ala Glu
                 455                 460                 465

 Phe Asn Leu Ser Ser Leu Ala Ser Gln Asn Glu Gly Met Asp Asp
                 470                 475                 480

 Thr Ser Ser Ala Ser Ser Arg Asn Ser Leu Gly Glu Gly Gln Glu
                 485                 490                 495

 Pro Lys Ser His Leu Lys Glu Glu Asp Pro Glu Glu Pro Arg Lys
                 500                 505                 510

 Pro Ala Ser Ala Pro Ser Glu Ala Cys Arg Arg Gln Ser Ser Gly
                 515                 520                 525

 Ala Gly Ala Glu His Leu Phe Leu Glu Asn Asp Val Ala Glu Ala
                 530                 535                 540

 Leu Leu Gln Glu Ser Glu Glu Ala Ser Glu Leu Lys Pro Val Glu
                 545                 550                 555

 Leu Asp Thr Ser Glu Gly Asn Ile Thr Lys Gln Leu Val Lys Arg
                 560                 565                 570

 Leu Thr Ser Ala Glu Val Pro Met Ala Thr Asp Arg Leu Leu Ser
                 575                 580                 585

 Glu Gly Ser Val Gly Gly Glu Ser Glu Gly Cys Arg Ser Phe Leu
                 590                 595                 600

 Asp Gly Ser Leu Glu Asp Ala Phe Asn Gly Leu Leu Leu Ala Leu
                 605                 610                 615

 Glu Pro His Lys Glu Gln Tyr Lys Glu Phe Gln Asp Leu Asn Gln
                 620                 625                 630

 Glu Val Met Asn Leu Asp Asp Ile Leu Lys Cys Lys Pro Ala Val
                 635                 640                 645

 Ser Arg Ser Arg Ser Ser Ser Leu Ser Leu Thr Val Glu Ser Ala
                 650                 655                 660

 Leu Glu Ser Phe Asp Phe Leu Asn Thr Ser Asp Phe Asp Glu Glu
                 665                 670                 675

 Glu Asp Gly Asp Glu Val Cys Asn Val Gly Gly Gly Ala Asp Ser
                 680                 685                 690

 Val Phe Ser Asp Thr Glu Thr Glu Lys His Ser Tyr Arg Ser Val
                 695                 700                 705

 His Pro Glu Ala Arg Gly His Leu Ser Glu Ala Leu Thr Glu Asp
                 710                 715                 720

 Thr Gly Val Gly Thr Ser Val Ala Gly Ser Pro Leu Pro Leu Thr
                 725                 730                 735

 Thr Gly Asn Glu Ser Leu Asp Ile Thr Ile Val Arg His Leu Gln
                 740                 745                 750

 Tyr Cys Thr Gln Leu Val Gln Gln Ile Val Phe Ser Ser Lys Thr
                 755                 760                 765

 Pro Phe Val Ala Arg Ser Leu Leu Glu Lys Leu Ser Arg Gln Ile
                 770                 775                 780

 Gln Val Met Glu Lys Leu Ala Ala Val Ser Asp Glu Asn Ile Gly
                 785                 790                 795

 Asn Ile Ser Ser Val Val Glu Ala Ile Pro Glu Phe His Lys Lys
                 800                 805                 810

 Leu Ser Leu Leu Ser Phe Trp Thr Lys Cys Cys Ser Pro Val Gly
                 815                 820                 825

 Val Tyr His Ser Pro Ala Asp Arg Val Met Lys Gln Leu Glu Ala
                 830                 835                 840

 Ser Phe Ala Arg Thr Val Asn Lys Glu Tyr Pro Gly Leu Ala Asp
                 845                 850                 855

 Pro Val Phe Arg Thr Leu Val Ser Gln Ile Leu Asp Gln Ala Glu
                 860                 865                 870

 Pro Leu Leu Ser Ser Ser Leu Ser Ser Glu Val Val Thr Val Phe
                 875                 880                 885

 Gln Tyr Tyr Ser Tyr Phe Thr Ser His Gly Val Ser Asp Leu Glu
                 890                 895                 900

 Ser Tyr Leu Ser Gln Leu Ala Arg Gln Val Ser Met Val Gln Thr
                 905                 910                 915

 Leu Gln Ser Leu Arg Asp Glu Lys Leu Leu Gln Thr Met Ser Asp
                 920                 925                 930

 Leu Ala Pro Ser Asn Leu Leu Ala Gln Gln Glu Val Leu Arg Thr
                 935                 940                 945

 Leu Ala Leu Leu Leu Thr Arg Glu Asp Asn Glu Val Ser Glu Ala
                 950                 955                 960

 Val Thr Leu Tyr Leu Ala Ala Ala Ser Lys Asn Gln His Phe Arg
                 965                 970                 975

 Glu Lys Ala Leu Leu Tyr Tyr Cys Glu Ala Leu Thr Lys Thr Asn
                 980                 985                 990

 Leu Gln Leu Gln Lys Ala Ala Cys Leu Ala Leu Lys Ile Leu Glu
                 995                1000                1005

 Ala Thr Glu Ser Ile Lys Met Leu Val Thr Leu Cys Gln Ser Asp
                1010                1015                1020

 Thr Glu Glu Ile Arg Asn Val Ala Ser Glu Thr Leu Leu Ser Leu
                1025                1030                1035

 Gly Glu Asp Gly Arg Leu Ala Tyr Glu Gln Leu Asp Lys Phe Pro
                1040                1045                1050

 Arg Asp Cys Val Lys Val Gly Gly Arg His Gly Thr Glu Val Ala
                1055                1060                1065

 Thr Ala Phe


<210> 2116
<211> 930
<212> DNA
<213> Homo sapien

<400> 2116
 attttttaaa ttattaggtg tgggcagaag aaaaagctag tgatcaacag 50

 tggcaatgga gctgtggagg acagaaagcc aagtggactc aacggagagg 100

 ccagcaagtc tcaggaaatg gtgcatttgg tgaacaagga gtcgtcagaa 150

 actccagacc agtttatgac agctgatgag acaaggaacc tgcagaatgt 200

 ggacatgaag attggggtgt aacacctaca ccattatctt ggaaagaaac 250

 aaccgttgga aacataacca ttacagggag ctgggacact taacagatgc 300

 aatgtgctac tgattgtttc attgcgaatc ttttttagca taaaattttc 350

 tactcttttt gttttttgtg ttttgttctt taaagtcagg tccaatttgt 400

 aaaaacagca ttgctttctg aaattagggc ccaattaata atcagcaaga 450

 atttgatcgt tccagttccc acttggaggc ctttcatccc tcgggtgtgc 500

 tatggatggc ttctaacaaa aactacacat atgtattcct gatcgccaac 550

 ctttccccca ccagctaagg acatttccca gggttaatag ggcctggtcc 600

 ctgggaggaa atttgaatgg gtccattttg cccttccata gcctaatccc 650

 tgggcattgt tttccactga ggttgggggt tggggtgtac tagttacata 700

 tcttcaacag accccctcta gaaatttttc agatgcttct gggagacacc 750

 caaagggtga agctatttat ctgtagtaaa ctatttatct gtgtttttga 800

 aatattaaac cctggatcag tcctttgatc agtataattt tttaaagtta 850

 ctttgtcaga ggcacaaaag ggtttaaact gattcataat aaatatctgt 900

 acttcttcga tcttcacctt ttgtgctgtg 930

<210> 2117
<211> 3394
<212> DNA
<213> Homo sapien

<400> 2117
 agcgggtcgg tgtgacaact gatcgggtga acgatgcacc actaaccacc 50

 atggaaacaa ggaaaaataa agcaagctca caggatctct cttcactgga 100

 ttgagagcct cagcctgccg actgagaaaa agagttccag gaaaaagaag 150

 gaatcccggc tgcagcctcc tgccttcctt tatattttaa aatagagaga 200

 taagattgcg tgcatgtgtg catatctata gtatatattt tgtacacttt 250

 gttacacaga cacacaaatg cacctattta taccgggcaa gaacacaacc 300

 atgtgattat ctcaaccaag gaactgagga atccagcacg caaggacatc 350

 ggaggtgggc tagcactgaa actgcttttc aagcatcatg ctgctattcc 400

 tgcaaatact gaagaagcat gggatttaaa tattttactt ctaaataaat 450

 gaattactca atctcctatg accatctata catactccac cttcaaaaag 500

 tacatcaata ttatatcatt aaggaaatag taaccttctc ttctccaata 550

 tgcatgacat ttttggacaa tgcaattgtg gcactggcac ttgtttcagt 600

 gaagaaaaac tttgtggttc tatggcattc atcatttgac aaatgcaagc 650

 atcttcctta tcaatcagct cctattgaac ttactagcac tgactgtgga 700

 atccttaagg gcccattaca tttctgaaga agaaagctaa gatgaaggac 750

 atgccactcc gaattcatgt gctacttggc ctagctatca ctacactagt 800

 acaagctgta gataaaaaag tggattgtcc acggttatgt acgtgtgaaa 850

 tcaggccttg gtttacaccc agatccattt atatggaagc atctacagtg 900

 gattgtaatg atttaggtct tttaactttc ccagccagat tgccagctaa 950

 cacacagatt cttctcctac agactaacaa tattgcaaaa attgaatact 1000

 ccacagactt tccagtaaac cttactagcc tggatttatc tcaaaacaat 1050

 ttatcttcag tcaccaatat taatgtaaaa aagatgcctc agctcctttc 1100

 tgtgtaccta gaggaaaaca aacttactga actgcctgaa aaatgtctgt 1150

 ccgaactgag caacttacaa gaactctata ttaatcacaa cttgctttct 1200

 acaatttcac ctggagcctt tattggccta cataatcttc ttcgacttca 1250

 tctcaattca aatagattgc agatgatcaa cagtaagtgg tttgatgctc 1300

 ttccaaatct agagattctg atgattgggg aaaatccaat tatcagaatc 1350

 aaagacatga actttaagcc tcttatcaat cttcgcagcc tggttatagc 1400

 tggtataaac ctcacagaaa taccagataa cgccttggtt ggactggaaa 1450

 acttagaaag catctctttt tacgataaca ggcttattaa agtaccccat 1500

 gttgctcttc aaaaagttgt aaatctcaaa tttttggatc taaataaaaa 1550

 tcctattaat agaatacgaa ggggtgattt tagcaatatg ctacacttaa 1600

 aagagttggg gataaataat atgcctgagc tgatttccat cgatagtctt 1650

 gctgtggata acctgccaga tttaagaaaa atagaagcta ctaacaaccc 1700

 tagattgtct tacattcacc ccaatgcatt tttcagactc cccaagctgg 1750

 aatcactcat gctgaacagc aatgctctca gtgccctgta ccatggtacc 1800

 attgagtctc tgccaaacct caaggaaatc agcatacaca gtaaccccat 1850

 caggtgtgac tgtgtcatcc gttggatgaa catgaacaaa accaacattc 1900

 gattcatgga gccagattca ctgttttgcg tggacccacc tgaattccaa 1950

 ggtcagaatg ttcggcaagt gcatttcagg gacatgatgg aaatttgtct 2000

 ccctcttata gctcctgaga gctttccttc taatctaaat gtagaagctg 2050

 ggagctatgt ttcctttcac tgtagagcta ctgcagaacc acagcctgaa 2100

 atctactgga taacaccttc tggtcaaaaa ctcttgccta ataccctgac 2150

 agacaagttc tatgtccatt ctgagggaac actagatata aatggcgtaa 2200

 ctcccaaaga agggggttta tatacttgta tagcaactaa cctagttggc 2250

 gctgacttga agtctgttat gatcaaagtg gatggatctt ttccacaaga 2300

 taacaatggc tctttgaata ttaaaataag agatattcat gccaattcag 2350

 ttttggtgtc ctggaaagca agttctaaaa ttctcaaatc tagtgttaaa 2400

 tggacagcct ttgtcaagac tgaaaattct catgctgcgc aaagtgctcg 2450

 aataccatct gatgtcaagg tatataatct tactcatctg aatccatcaa 2500

 ctgagtataa aatttgtatt gatattccca ccatctatca gaaaaacaga 2550

 aaaaaatgtg taaatgtcac caccaaaggt ttgcaccctg atcaaaaaga 2600

 gtatgaaaag aataatacca caacacttat ggcctgtctt ggaggccttc 2650

 tggggattat tggtgtgata tgtcttatca gctgcctctc tccagaaatg 2700

 aactgtgatg gtggacacag ctatgtgagg aattacttac agaaaccaac 2750

 ctttgcatta ggtgagcttt atcctcctct gataaatctc tgggaagcag 2800

 gaaaagaaaa aagtacatca ctgaaagtaa aagcaactgt tataggttta 2850

 ccaacaaata tgtcctaaaa accaccaagg aaacctactc caaaaatgaa 2900

 caaaaaaaaa aaaagcgaaa gactgcagtt gtgctaaaaa caaaacaaaa 2950

 caaacaaaca aacaaaaaag taaaaaaaga ttactttcga gagagaagtt 3000

 taagcttcac caatgctgct cctgaccaat ggaaatatgt acaacttcag 3050

 cattttaagt aactggcttc aaggggtact gtggcaacca aataaaataa 3100

 ctccattttc taaaactttc atgtaacttt tatgtctgga ctacagttca 3150

 agtggacaaa aacatttctg tatttttttt aagtaaataa gagtagttga 3200

 actgagcaat acctcctcct gtgttgtatt acacatatta gccacgagtt 3250

 tttgcagtga ccagataaac ttgaattgac acgtggtgta ataaaatgga 3300

 caaattctgt agagtagaca cagtgagtat gtggacctct tttataagga 3350

 aaaatacatt ttggattaaa atcaaaaaaa aaaaaaaaaa aaaa 3394

<210> 2118
<211> 708
<212> PRT
<213> Homo sapien

<400> 2118
 Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala
   1               5                  10                  15

 Ile Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro
                  20                  25                  30

 Arg Leu Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser
                  35                  40                  45

 Ile Tyr Met Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu
                  50                  55                  60

 Leu Thr Phe Pro Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu
                  65                  70                  75

 Leu Gln Thr Asn Asn Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe
                  80                  85                  90

 Pro Val Asn Leu Thr Ser Leu Asp Leu Ser Gln Asn Asn Leu Ser
                  95                 100                 105

 Ser Val Thr Asn Ile Asn Val Lys Lys Met Pro Gln Leu Leu Ser
                 110                 115                 120

 Val Tyr Leu Glu Glu Asn Lys Leu Thr Glu Leu Pro Glu Lys Cys
                 125                 130                 135

 Leu Ser Glu Leu Ser Asn Leu Gln Glu Leu Tyr Ile Asn His Asn
                 140                 145                 150

 Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe Ile Gly Leu His Asn
                 155                 160                 165

 Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu Gln Met Ile Asn
                 170                 175                 180

 Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile Leu Met Ile
                 185                 190                 195

 Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe Lys Pro
                 200                 205                 210

 Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu Thr
                 215                 220                 225

 Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser
                 230                 235                 240

 Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala
                 245                 250                 255

 Leu Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn
                 260                 265                 270

 Pro Ile Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His
                 275                 280                 285

 Leu Lys Glu Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile
                 290                 295                 300

 Asp Ser Leu Ala Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu
                 305                 310                 315

 Ala Thr Asn Asn Pro Arg Leu Ser Tyr Ile His Pro Asn Ala Phe
                 320                 325                 330

 Phe Arg Leu Pro Lys Leu Glu Ser Leu Met Leu Asn Ser Asn Ala
                 335                 340                 345

 Leu Ser Ala Leu Tyr His Gly Thr Ile Glu Ser Leu Pro Asn Leu
                 350                 355                 360

 Lys Glu Ile Ser Ile His Ser Asn Pro Ile Arg Cys Asp Cys Val
                 365                 370                 375

 Ile Arg Trp Met Asn Met Asn Lys Thr Asn Ile Arg Phe Met Glu
                 380                 385                 390

 Pro Asp Ser Leu Phe Cys Val Asp Pro Pro Glu Phe Gln Gly Gln
                 395                 400                 405

 Asn Val Arg Gln Val His Phe Arg Asp Met Met Glu Ile Cys Leu
                 410                 415                 420

 Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu Asn Val Glu
                 425                 430                 435

 Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala Glu Pro
                 440                 445                 450

 Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu Leu
                 455                 460                 465

 Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr
                 470                 475                 480

 Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr
                 485                 490                 495

 Cys Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met
                 500                 505                 510

 Ile Lys Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu
                 515                 520                 525

 Asn Ile Lys Ile Arg Asp Ile His Ala Asn Ser Val Leu Val Ser
                 530                 535                 540

 Trp Lys Ala Ser Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr
                 545                 550                 555

 Ala Phe Val Lys Thr Glu Asn Ser His Ala Ala Gln Ser Ala Arg
                 560                 565                 570

 Ile Pro Ser Asp Val Lys Val Tyr Asn Leu Thr His Leu Asn Pro
                 575                 580                 585

 Ser Thr Glu Tyr Lys Ile Cys Ile Asp Ile Pro Thr Ile Tyr Gln
                 590                 595                 600

 Lys Asn Arg Lys Lys Cys Val Asn Val Thr Thr Lys Gly Leu His
                 605                 610                 615

 Pro Asp Gln Lys Glu Tyr Glu Lys Asn Asn Thr Thr Thr Leu Met
                 620                 625                 630

 Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile Gly Val Ile Cys Leu
                 635                 640                 645

 Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp Gly Gly His Ser
                 650                 655                 660

 Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala Leu Gly Glu
                 665                 670                 675

 Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys Glu Lys
                 680                 685                 690

 Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro Thr
                 695                 700                 705

 Asn Met Ser


<210> 2119
<211> 2961
<212> DNA
<213> Homo sapien

<400> 2119
 acatactcca ccttcaaaaa gtacatcaat attatatcat taaggaaata 50

 gtaaccttct cttctccaat atgcatgaca tttttggaca atgcaattgt 100

 ggcactggca cttatttcag tgaagaaaaa ctttgtggtt ctatggcatt 150

 catcatttga caaatgcaag catcttcctt atcaatcagc tcctattgaa 200

 cttactagca ctgactgtgg aatccttaag ggcccattac atttctgaag 250

 aagaaagcta agatgaagga catgccactc cgaattcatg tgctacttgg 300

 cctagctatc actacactag tacaagctgt agataaaaaa gtggattgtc 350

 cacggttatg tacgtgtgaa atcaggcctt ggtttacacc cagatccatt 400

 tatatggaag catctacagt ggattgtaat gatttaggtc ttttaacttt 450

 cccagccaga ttgccagcta acacacagat tcttctccta cagactaaca 500

 atattgcaaa aattgaatac tccacagact ttccagtaaa ccttactggc 550

 ctggatttat ctcaaaacaa tttatcttca gtcaccaata ttaatgtaaa 600

 aaagatgcct cagctccttt ctgtgtacct agaggaaaac aaacttactg 650

 aactgcctga aaaatgtctg tccgaactga gcaacttaca agaactctat 700

 attaatcaca acttgctttc tacaatttca cctggagcct ttattggcct 750

 acataatctt cttcgacttc atctcaattc aaatagattg cagatgatca 800

 acagtaagtg gtttgatgct cttccaaatc tagagattct gatgattggg 850

 gaaaatccaa ttatcagaat caaagacatg aactttaagc ctcttatcaa 900

 tcttcgcagc ctggttatag ctggtataaa cctcacagaa ataccagata 950

 acgccttggt tggactggaa aacttagaaa gcatctcttt ttacgataac 1000

 aggcttatta aagtacccca tgttgctctt caaaaagttg taaatctcaa 1050

 atttttggat ctaaataaaa atcctattaa tagaatacga aggggtgatt 1100

 ttagcaatat gctacactta aaagagttgg ggataaataa tatgcctgag 1150

 ctgatttcca tcgatagtct tgctgtggat aacctgccag atttaagaaa 1200

 aatagaagct actaacaacc ctagattgtc ttacattcac cccaatgcat 1250

 ttttcagact ccccaagctg gaatcactca tgctgaacag caatgctctc 1300

 agtgccctgt accatggtac cattgagtct ctgccaaacc tcaaggaaat 1350

 cagcatacac agtaacccca tcaggtgtga ctgtgtcatc cgttggatga 1400

 acatgaacaa aaccaacatt cgattcatgg agccagattc actgttttgc 1450

 gtggacccac ctgaattcca aggtcagaat gttcggcaag tgcatttcag 1500

 ggacatgatg gaaatttgtc tccctcttat agctcctgag agctttcctt 1550

 ctaatctaaa tgtagaagct gggagctatg tttcctttca ctgtagagct 1600

 actgcagaac cacagcctga aatctactgg ataacacctt ctggtcaaaa 1650

 actcttgcct aataccctga cagacaagtt ctatgtccat tctgagggaa 1700

 cactagatat aaatggcgta actcccaaag aagggggttt atatacttgt 1750

 atagcaacta acctagttgg cgctgacttg aagtctgtta tgatcaaagt 1800

 ggatggatct tttccacaag ataacaatgg ctctttgaat attaaaataa 1850

 gagatattca ggccaattca gttttggtgt cctggaaagc aagttctaaa 1900

 attctcaaat ctagtgttaa atggacagcc tttgtcaaga ctgaaaattc 1950

 tcatgctgcg caaagtgctc gaataccatc tgatgtcaag gtatataatc 2000

 ttactcatct gaatccatca actgagtata aaatttgtat tgatattccc 2050

 accatctatc agaaaaacag aaaaaaatgt gtaaatgtca ccaccaaagg 2100

 tttgcaccct gatcaaaaag agtatgaaaa gaataatacc acaacactta 2150

 tggcctgtct tggaggcctt ctggggatta ttggtgtgat atgtcttatc 2200

 agctgcctct ctccagaaat gaactgtgat ggtggacaca gctatgtgag 2250

 gaattactta cagaaaccaa cctttgcatt aggtgagctt tatcctcctc 2300

 tgataaatct ctgggaagca ggaaaagaaa aaagtacatc actgaaagta 2350

 aaagcaactg ttataggttt accaacaaat atgtcctaaa aaccaccaag 2400

 gaaacctact ccaaaaatga acaaaaaaaa aaaaaagcga aagactgcag 2450

 ttgtgctaaa aacaaaacaa aacaaacaaa caaacaaaaa agtaaaaaaa 2500

 gattactttc gagagagaag tttaagcttc accaatgctg ctcctgacca 2550

 atggaaatat gtacaacttc agcattttaa gtaactggct tcaaggggta 2600

 ctgtggcaac caaataaaat aactccattt tctaaaactt tcatgtaact 2650

 tttatgtctg gactacagtt caagtggaca aaaacatttc tgtatttttt 2700

 ttaagtaaat aagagtagtt gaactgagca atacctcctc ctgtgttgta 2750

 ttacacatat tagccacgag tttttgcagt gaccagataa acttgaattg 2800

 acacgtggtg taataaaatg gacaaattct gtagagtaga cacagtgagt 2850

 atgtggacct cttttataag gaaaaataca ttttggatta aaatcaattg 2900

 cttctgtctt gttttgtttc taaataaaga ataatttctg ggaaaaaaaa 2950

 aaaaaaaaaa a 2961

<210> 2120
<211> 708
<212> PRT
<213> Homo sapien

<400> 2120
 Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala
   1               5                  10                  15

 Ile Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro
                  20                  25                  30

 Arg Leu Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser
                  35                  40                  45

 Ile Tyr Met Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu
                  50                  55                  60

 Leu Thr Phe Pro Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu
                  65                  70                  75

 Leu Gln Thr Asn Asn Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe
                  80                  85                  90

 Pro Val Asn Leu Thr Gly Leu Asp Leu Ser Gln Asn Asn Leu Ser
                  95                 100                 105

 Ser Val Thr Asn Ile Asn Val Lys Lys Met Pro Gln Leu Leu Ser
                 110                 115                 120

 Val Tyr Leu Glu Glu Asn Lys Leu Thr Glu Leu Pro Glu Lys Cys
                 125                 130                 135

 Leu Ser Glu Leu Ser Asn Leu Gln Glu Leu Tyr Ile Asn His Asn
                 140                 145                 150

 Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe Ile Gly Leu His Asn
                 155                 160                 165

 Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu Gln Met Ile Asn
                 170                 175                 180

 Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile Leu Met Ile
                 185                 190                 195

 Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe Lys Pro
                 200                 205                 210

 Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu Thr
                 215                 220                 225

 Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser
                 230                 235                 240

 Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala
                 245                 250                 255

 Leu Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn
                 260                 265                 270

 Pro Ile Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His
                 275                 280                 285

 Leu Lys Glu Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile
                 290                 295                 300

 Asp Ser Leu Ala Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu
                 305                 310                 315

 Ala Thr Asn Asn Pro Arg Leu Ser Tyr Ile His Pro Asn Ala Phe
                 320                 325                 330

 Phe Arg Leu Pro Lys Leu Glu Ser Leu Met Leu Asn Ser Asn Ala
                 335                 340                 345

 Leu Ser Ala Leu Tyr His Gly Thr Ile Glu Ser Leu Pro Asn Leu
                 350                 355                 360

 Lys Glu Ile Ser Ile His Ser Asn Pro Ile Arg Cys Asp Cys Val
                 365                 370                 375

 Ile Arg Trp Met Asn Met Asn Lys Thr Asn Ile Arg Phe Met Glu
                 380                 385                 390

 Pro Asp Ser Leu Phe Cys Val Asp Pro Pro Glu Phe Gln Gly Gln
                 395                 400                 405

 Asn Val Arg Gln Val His Phe Arg Asp Met Met Glu Ile Cys Leu
                 410                 415                 420

 Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu Asn Val Glu
                 425                 430                 435

 Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala Glu Pro
                 440                 445                 450

 Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu Leu
                 455                 460                 465

 Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr
                 470                 475                 480

 Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr
                 485                 490                 495

 Cys Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met
                 500                 505                 510

 Ile Lys Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu
                 515                 520                 525

 Asn Ile Lys Ile Arg Asp Ile Gln Ala Asn Ser Val Leu Val Ser
                 530                 535                 540

 Trp Lys Ala Ser Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr
                 545                 550                 555

 Ala Phe Val Lys Thr Glu Asn Ser His Ala Ala Gln Ser Ala Arg
                 560                 565                 570

 Ile Pro Ser Asp Val Lys Val Tyr Asn Leu Thr His Leu Asn Pro
                 575                 580                 585

 Ser Thr Glu Tyr Lys Ile Cys Ile Asp Ile Pro Thr Ile Tyr Gln
                 590                 595                 600

 Lys Asn Arg Lys Lys Cys Val Asn Val Thr Thr Lys Gly Leu His
                 605                 610                 615

 Pro Asp Gln Lys Glu Tyr Glu Lys Asn Asn Thr Thr Thr Leu Met
                 620                 625                 630

 Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile Gly Val Ile Cys Leu
                 635                 640                 645

 Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp Gly Gly His Ser
                 650                 655                 660

 Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala Leu Gly Glu
                 665                 670                 675

 Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys Glu Lys
                 680                 685                 690

 Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro Thr
                 695                 700                 705

 Asn Met Ser


<210> 2121
<211> 1283
<212> DNA
<213> Homo sapien

<400> 2121
 cggacgcgtg ggtgctgtgt gggataaaca gtaatggcgg aggctgcaac 50

 tcccggaaca acagccacaa catcaggagc aggagcggca gcggcgacgg 100

 cggcagcagc ctcccccacc ccgatcccca cagtcaccgc cccgtccctg 150

 ggggcgggcg gagggggcgg cggcagcgac ggcagcggcg gcggctggac 200

 taaacaggtc acctgcaggt attttatgca tggggtttgt aaggaaggag 250

 acaactgtcg ctactcgcat gacctctctg acagtccgta tagtgtagtg 300

 tgcaagtatt ttcagcgagg gtactgtatt tatggagacc gctgcagata 350

 tgaacatagc aagccattga aacaggaaga agcaactgct acagagctaa 400

 ctacaaagtc atcccttgct gcttcctcaa gtctctcatc gatagttgga 450

 ccacttgttg aaatgaatac aggcgaagct gagtcaagaa attcaaactt 500

 tgcaactgta ggagcaggtt cagaggactg ggtgaatgct attgagtttg 550

 ttcctgggca accctactgt ggccgtactg cgccttcctg cactgaagca 600

 cccctgcagg gctcagtgac caaggaagaa tcagagaaag agcaaaccgc 650

 cgtggagaca aagaagcagc tgtgccccta tgctgcagtg ggagaaagcc 700

 aaccccagtg agcgccgctt cgggatcctc tccaactgca accacaccta 750

 ctgtctcaag tgcattcgca agtggaggag tgctaagcaa tttgagagca 800

 agatcataaa gtgagactcc tccccagtct tcatttgtgc tttctctttt 850

 ggggaagaat ttagtaactt gtgccaactt tcaaccagat ggaccgcatt 900

 taaatgcatg cattttatct tgaaactggg atattctaat ggggatttct 950

 tctttgtatt tcagctagct tctaggttag ttggtctatc tacttttatt 1000

 tgaatgagga aaccctgtgt atcagttaga atcttcgtgc tttttctgag 1050

 gagattgtgt ttaatggatt attagccagt ttaggctcag tgaacaaact 1100

 gatctagctc tgaatgtatg tttcctgacg ttttacattt ccactttcct 1150

 attccattca ttaagctagc caacaatcca ccatccttta aagattgttc 1200

 tcataactga acaaaaacca cataatctaa acagagcaaa gctacaagaa 1250

 ataaatttat ttaaacgaaa aaaaaaaaaa aaa 1283

<210> 2122
<211> 225
<212> PRT
<213> Homo sapien

<400> 2122
 Met Ala Glu Ala Ala Thr Pro Gly Thr Thr Ala Thr Thr Ser Gly
   1               5                  10                  15

 Ala Gly Ala Ala Ala Ala Thr Ala Ala Ala Ala Ser Pro Thr Pro
                  20                  25                  30

 Ile Pro Thr Val Thr Ala Pro Ser Leu Gly Ala Gly Gly Gly Gly
                  35                  40                  45

 Gly Gly Ser Asp Gly Ser Gly Gly Gly Trp Thr Lys Gln Val Thr
                  50                  55                  60

 Cys Arg Tyr Phe Met His Gly Val Cys Lys Glu Gly Asp Asn Cys
                  65                  70                  75

 Arg Tyr Ser His Asp Leu Ser Asp Ser Pro Tyr Ser Val Val Cys
                  80                  85                  90

 Lys Tyr Phe Gln Arg Gly Tyr Cys Ile Tyr Gly Asp Arg Cys Arg
                  95                 100                 105

 Tyr Glu His Ser Lys Pro Leu Lys Gln Glu Glu Ala Thr Ala Thr
                 110                 115                 120

 Glu Leu Thr Thr Lys Ser Ser Leu Ala Ala Ser Ser Ser Leu Ser
                 125                 130                 135

 Ser Ile Val Gly Pro Leu Val Glu Met Asn Thr Gly Glu Ala Glu
                 140                 145                 150

 Ser Arg Asn Ser Asn Phe Ala Thr Val Gly Ala Gly Ser Glu Asp
                 155                 160                 165

 Trp Val Asn Ala Ile Glu Phe Val Pro Gly Gln Pro Tyr Cys Gly
                 170                 175                 180

 Arg Thr Ala Pro Ser Cys Thr Glu Ala Pro Leu Gln Gly Ser Val
                 185                 190                 195

 Thr Lys Glu Glu Ser Glu Lys Glu Gln Thr Ala Val Glu Thr Lys
                 200                 205                 210

 Lys Gln Leu Cys Pro Tyr Ala Ala Val Gly Glu Ser Gln Pro Gln
                 215                 220                 225

<210> 2123
<211> 1666
<212> DNA
<213> Homo sapien

<400> 2123
 atttgctttc tctttttcct ttcttccgga tgagaggcta agccataata 50

 gaaagaatgg agaattattg attgaccgtc tttattctgt gggctctgat 100

 tctccaatgg gaataccaag ggatggtttt ccatactgga acccaaaggt 150

 aaagacactc aaggacagac atttttggca gagcatagat gaaaatggca 200

 agttccctgg ctttccttct gctcaacttt catgtctccc tcctcttggt 250

 ccagctgctc actccttgct cagctcagtt ttctgtgctt ggaccctctg 300

 ggcccatcct ggccatggtg ggtgaagacg ctgatctgcc ctgtcacctg 350

 ttcccgacca tgagtgcaga gaccatggag ctgaagtggg taagttccag 400

 cctaaggcag gtggtgaacg tgtatgcaga tggaaaggaa gtggaagaca 450

 ggcagagtgc accgtatcga gggagaactt cgattctgcg ggatggcatc 500

 actgcaggga aggctgctct ccgaatacac aacgtcacag cctctgacag 550

 tggaaagtac ttgtgttatt tccaagatgg tgacttctat gaaaaagccc 600

 tggtggagct gaaggttgca gcactgggtt ctaatcttca cgtcgaagtg 650

 aagggttatg aggatggagg gatccatctg gagtgcaggt ccaccggctg 700

 gtacccccaa ccccaaatac agtggagcaa cgccaaggga gagaacatcc 750

 cagctgtgga agcacctgtg gttgcagatg gagtgggcct atatgaagta 800

 gcagcatctg tgatcatgag aggcggctcc ggggagggtg tatcctgcat 850

 catcagaaat tccctcctcg gcctggaaaa gacagccagc atttccatcg 900

 cagacccctt cttcaggagc gcccagccct ggatcgcagc cctggcaggg 950

 accctgccta tcttgctgct gcttctcgcc ggagccagtt acttcttgtg 1000

 gagacaacag aaggaaataa ctgctctgtc cagtgagata gaaagtgagc 1050

 aagagatgaa agaaatggga tatgctgcaa cagagcggga aataagccta 1100

 agagagagcc tccaggagga actcaagagg aaaaaatcca gtacttgact 1150

 cgtggagagg agtcttcgtc cgataccaat aagtcagcct gatgctctaa 1200

 tggaaaaatg gccctcttca agcctggtga ggaaatgctt cagatgaggc 1250

 tccaccttgt taaataaatt ggatgtatgg aaaaatagac tgcagaaaag 1300

 gggaactcat ttagctcacg agtggtcgag tgaagattga aaattaacct 1350

 ctgagggcca gcacagcagc tcatgcctgt aatcctagca ctttggaagg 1400

 ctgaggaggg cggatcacaa ggtcaggaga tcaagaccat cctggctaac 1450

 acggtgaaac cccgtctcta ctaaaaatac aaaaaataaa aaattagccg 1500

 ggcatggtga cgggcacctg tagtcccagc tactcgggag gctgaggcag 1550

 gagaatggca tgaacccgga aggcagagct tgcagtgagc cgagatcacg 1600

 ccactgcact ccagcctggg agacagagcg agactctgtc tcaagaaaaa 1650

 aaaaaaaaaa aaaaaa 1666

<210> 2124
<211> 319
<212> PRT
<213> Homo sapien

<400> 2124
 Met Lys Met Ala Ser Ser Leu Ala Phe Leu Leu Leu Asn Phe His
   1               5                  10                  15

 Val Ser Leu Leu Leu Val Gln Leu Leu Thr Pro Cys Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Lys Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asn Leu
                 140                 145                 150

 His Val Glu Val Lys Gly Tyr Glu Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Gln Trp Ser
                 170                 175                 180

 Asn Ala Lys Gly Glu Asn Ile Pro Ala Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Glu Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Gly Ser Gly Glu Gly Val Ser Cys Ile Ile Arg Asn Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Pro Trp Ile Ala Ala Leu Ala Gly Thr
                 245                 250                 255

 Leu Pro Ile Leu Leu Leu Leu Leu Ala Gly Ala Ser Tyr Phe Leu
                 260                 265                 270

 Trp Arg Gln Gln Lys Glu Ile Thr Ala Leu Ser Ser Glu Ile Glu
                 275                 280                 285

 Ser Glu Gln Glu Met Lys Glu Met Gly Tyr Ala Ala Thr Glu Arg
                 290                 295                 300

 Glu Ile Ser Leu Arg Glu Ser Leu Gln Glu Glu Leu Lys Arg Lys
                 305                 310                 315

 Lys Ser Ser Thr


<210> 2125
<211> 2894
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2236, 2238, 2738
<223> Unknown base

<400> 2125
 gggcggacag gcacagaggg agggagcgag cgagcagtga gtaagccagc 50

 aagggcggtc gggtcccgag gtcagccgag atttctcagg tccctccggc 100

 cccctccctg gagtccacag cgcctccggt gtccagagga tcggacacgg 150

 cccggcccgg ccatggcctc gttgctgaag gtggatcagg aagtgaagct 200

 caaggttgat tctttcaggg agcggatcac aagtaaggca gaagacttgg 250

 tggcaaattt tttcccaaag aagttattag aacttgatag ttttctgaag 300

 gaaccaatct taaacatcca tgacctaact cagatccact ctgacatgaa 350

 tctcccagtc cctgacccca ttcttctcac caatagccat gatggactgg 400

 atggtcccac ttataagaag cgaaggttgg atgagtgtga agaagccttc 450

 caaggaacca aggtgtttgt gatgcccaat gggatgctga aaagcaacca 500

 gcagctggtg gacattattg agaaagtgaa acctgagatc cggctgttga 550

 ttgagaaatg taacacgcct tcaggcaaag gtcctcatat atgttttgac 600

 ctccaggtca aaatgtgggt acagctcctg attcccagga tagaagatgg 650

 aaacaacttt ggggtgtcca ttcaggagga aacagttgca gagctaagaa 700

 ctgttgagag tgaagctgca tcttatctgg accagatttc tagatattat 750

 attacaagag ccaaattggt ttctaaaata gctaaatatc cccatgtgga 800

 ggactatcgc cgcaccgtga cagagattga tgagaaagaa tatatcagcc 850

 ttcggctcat catatcagag ctgaggaatc aatatgtcac tctacatgac 900

 atgatcctga aaaatatcga gaagatcaaa cggccccgga gcagcaatgc 950

 agagactctg tactgaggcc agggccaggg ccaggggact ctgtgagtct 1000

 ggctcaagac cgacattgcc ttggtttgtt acatgactat cgtgatgggg 1050

 aaactggctg gaaatagtaa tcacacctct ctgtttttag ttagagtcta 1100

 atgaaactct catctagttc tgtgatgtgt ttacctcttt tttcaggcct 1150

 caggaactct tctatttcct tccctaatac cccacaccca acctgtcgta 1200

 atttctggag aactccaggt ttgtgtgtgc aggatgttgg cacaaaaata 1250

 cctgtgtttt cattctcccc ctctctccct cctgtgtctg gcgctttatg 1300

 ttttcttccg tttgataatt agttggttaa aagctgaggg aaccggaagg 1350

 aaagtgctag gtgtttttta ggaactaggg tggagggggg acgaacttct 1400

 cttcctcaca tgaggttact gtttctttcc tctgtggggc attggatcct 1450

 cccacagttg ccctggtgat gacttaggac ttcccatctg tgacatccca 1500

 ctttgaatct tgatcgtgac aagaaatacc ttaggccttc agtcaattcc 1550

 gaagctcctt cagttgtttt tataatgggc gtttcacatg cacatatgtg 1600

 tatgcatgta tacgcccata cagacatgca cacacagact cctactccat 1650

 tagctaacat accctccctc tccacaaccc gtgtcacata cctttcagga 1700

 ggtgacagtt gtcttagttg tcatctaccc agacaaacgt cctgggcccg 1750

 tcctccctcc tgatactgta gcctcttggt acccagggtg agttggtgga 1800

 gaacagagag atgagaagca gagggcttgg ggaaagcctg ttcctctctg 1850

 actcagccct ttttggcatt attgcaagag cttgactcct ggttgccttt 1900

 tcccagccag ttttcagttg gggtgaaggt ttctgcaagt gtgaggtcca 1950

 gatgctgctg ctcatgttgg gctttccttt tgggaactat ttctctttat 2000

 ttatagtgtc gggcttccgg ggaaagcaat cattggtgtg tatgtgtatg 2050

 tgccatgcac acacgtgcat atatacacat ttgtgtatgt ggaaatgtgc 2100

 tgggcaagtc aaaactatag aagagttgcc tcctgtctct cgaatcttcc 2150

 agagatatca cttaattgtt aacagctttt gtgttaatcc ccttcatccc 2200

 ctagcacttt tattctacca cggctggaga gttgananct acagtcagcc 2250

 tgccagtgac tcttagtgtc tgtttctgac ttatttttcc tgtctctgtc 2300

 ttccaacccc caataatatt tcccaccggg gatgcatcat ttttactccc 2350

 aatattctgt agagagggag tcaggatgct gtcttcccac gaatagtact 2400

 cagtaacaaa ccaattgcat tttagttggg cagtgctccc acccaccctg 2450

 cagatccctc cagctaaaac ccttccccct tccctccatg tgtttctcag 2500

 tttcccgttc gtttgttgga ctgttccact gcccctcctc ctcaccctat 2550

 cacccatgga tcgtaatgta aaattctttt accatgtcaa gaaattatta 2600

 aaaatacagg tactttgacc tctttctaaa gccgcagacc ctggtgcaat 2650

 gctctggtgg ctagggatgt actcatgctc atatgtgtgc acgcttggac 2700

 acccacctcc atggacacct agccaccctg ttgtgtgncc ttatgccagt 2750

 tgagctgaat cttttcccca gtatagtgga aagactgagg cttctgccta 2800

 ctgagcaagg ttgggtgctt catttgtgtt cagtctgaat tatgggaaag 2850

 ttagctcttc ccagacctaa gctgccttct ctccctactt tcag 2894

<210> 2126
<211> 267
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2236, 2238, 2738
<223> Unknown amino acid

<400> 2126
 Met Ala Ser Leu Leu Lys Val Asp Gln Glu Val Lys Leu Lys Val
   1               5                  10                  15

 Asp Ser Phe Arg Glu Arg Ile Thr Ser Lys Ala Glu Asp Leu Val
                  20                  25                  30

 Ala Asn Phe Phe Pro Lys Lys Leu Leu Glu Leu Asp Ser Phe Leu
                  35                  40                  45

 Lys Glu Pro Ile Leu Asn Ile His Asp Leu Thr Gln Ile His Ser
                  50                  55                  60

 Asp Met Asn Leu Pro Val Pro Asp Pro Ile Leu Leu Thr Asn Ser
                  65                  70                  75

 His Asp Gly Leu Asp Gly Pro Thr Tyr Lys Lys Arg Arg Leu Asp
                  80                  85                  90

 Glu Cys Glu Glu Ala Phe Gln Gly Thr Lys Val Phe Val Met Pro
                  95                 100                 105

 Asn Gly Met Leu Lys Ser Asn Gln Gln Leu Val Asp Ile Ile Glu
                 110                 115                 120

 Lys Val Lys Pro Glu Ile Arg Leu Leu Ile Glu Lys Cys Asn Thr
                 125                 130                 135

 Pro Ser Gly Lys Gly Pro His Ile Cys Phe Asp Leu Gln Val Lys
                 140                 145                 150

 Met Trp Val Gln Leu Leu Ile Pro Arg Ile Glu Asp Gly Asn Asn
                 155                 160                 165

 Phe Gly Val Ser Ile Gln Glu Glu Thr Val Ala Glu Leu Arg Thr
                 170                 175                 180

 Val Glu Ser Glu Ala Ala Ser Tyr Leu Asp Gln Ile Ser Arg Tyr
                 185                 190                 195

 Tyr Ile Thr Arg Ala Lys Leu Val Ser Lys Ile Ala Lys Tyr Pro
                 200                 205                 210

 His Val Glu Asp Tyr Arg Arg Thr Val Thr Glu Ile Asp Glu Lys
                 215                 220                 225

 Glu Tyr Ile Ser Leu Arg Leu Ile Ile Ser Glu Leu Arg Asn Gln
                 230                 235                 240

 Tyr Val Thr Leu His Asp Met Ile Leu Lys Asn Ile Glu Lys Ile
                 245                 250                 255

 Lys Arg Pro Arg Ser Ser Asn Ala Glu Thr Leu Tyr
                 260                 265

<210> 2127
<211> 1908
<212> DNA
<213> Homo sapien

<400> 2127
 ctctgtctca ttccctcgcg ctctctcggg caacatggcg ggtgtggagg 50

 aggtagcggc ctccgggagc cacctgaatg gcgacctgga tccagacgac 100

 agggaagaag gagctgcctc tacggctgag gaagcagcca agaaaaaaag 150

 acgaaagaag aagaagagca aagggccttc tgcagcaggg gaacaggaac 200

 ctgataaaga atcaggagcc tcagtggatg aagtagcaag acagttggaa 250

 agatcagcat tggaagataa agaaagagat gaagatgatg aagatggaga 300

 tggcgatgga gatggagcaa ctggaaagaa gaagaaaaag aagaagaaga 350

 agagaggacc aaaagttcaa acagaccctc cctcagttcc aatatgtgac 400

 ctgtatccta atggtgtatt tcccaaagga caagaatgcg aatacccacc 450

 cacacaagat gggcgaacag ctgcttggag aactacaagt gaagaaaaga 500

 aagcattaga tcaggcaagt gaagagattt ggaatgattt tcgagaagct 550

 gcagaagcac atcgacaagt tagaaaatac gtaatgagct ggatcaagcc 600

 tgggatgaca atgatagaaa tctgtgaaaa gttggaagac tgttcacgca 650

 agttaataaa agagaatgga ttaaatgcag gcctggcatt tcctactgga 700

 tgttctctca ataattgtgc tgcccattat actcccaatg ccggtgacac 750

 aacagtatta cagtatgatg acatctgtaa aatagacttt ggaacacata 800

 taagtggtag gattattgac tgtgctttta ctgtcacttt taatcccaaa 850

 tatgatacgt tattaaaagc tgtaaaagat gctactaaca ctggaataaa 900

 gtgtgctgga attgatgttc gtctgtgtga tgttggtgag gccatccaag 950

 aagttatgga gtcctatgaa gttgaaatag atgggaagac atatcaagtg 1000

 aaaccaatcc gtaatctaaa tggacattca attgggcaat atagaataca 1050

 tgctggaaaa acagtgccga ttgtgaaagg aggggaggca acaagaatgg 1100

 aggaaggaga agtatatgca attgaaacct ttggtagtac aggaaaaggt 1150

 gttgttcatg atgatatgga atgttcacat tacatgaaaa attttgatgt 1200

 tggacatgtg ccaataaggc ttccaagaac aaaacacttg ttaaatgtca 1250

 tcaatgaaaa ctttggaacc cttgccttct gccgcagatg gctggatcgc 1300

 ttgggagaaa gtaaatactt gatggctctg aagaatctgt gtgacttggg 1350

 cattgtagat ccatatccac cattatgtga cattaaagga tcatatacag 1400

 cgcaatttga acataccatc ctgttgcgtc caacatgtaa agaagttgtc 1450

 agcagaggag atgactatta aacttagtcc aaagccacct caacaccttt 1500

 attttctgag ctttgttgga aaacatgata ccagaattaa tttgccacat 1550

 gttgtctgtt ttaacagtgg acccatgtaa tacttttatc catgtttaaa 1600

 aagaaggaat ttggacaaag gcaaaccgtc taatgtaatt aaccaacgaa 1650

 aaagctttcc ggacttttaa atgctaactg tttttcccct tcctgtctag 1700

 gaaaatgcta taaagctcaa attagttagg aatgacttat acgttttgtt 1750

 ttgaatacct aagagatact ttttggatat ttatattgcc atattcttac 1800

 ttgaatgctt tgaatgacta catccagttc tgcacctata ccctctggtg 1850

 ttgcttttta accttcctgg aatccatttc taaaaaataa agacattttc 1900

 agatctga 1908

<210> 2128
<211> 478
<212> PRT
<213> Homo sapien

<400> 2128
 Met Ala Gly Val Glu Glu Val Ala Ala Ser Gly Ser His Leu Asn
   1               5                  10                  15

 Gly Asp Leu Asp Pro Asp Asp Arg Glu Glu Gly Ala Ala Ser Thr
                  20                  25                  30

 Ala Glu Glu Ala Ala Lys Lys Lys Arg Arg Lys Lys Lys Lys Ser
                  35                  40                  45

 Lys Gly Pro Ser Ala Ala Gly Glu Gln Glu Pro Asp Lys Glu Ser
                  50                  55                  60

 Gly Ala Ser Val Asp Glu Val Ala Arg Gln Leu Glu Arg Ser Ala
                  65                  70                  75

 Leu Glu Asp Lys Glu Arg Asp Glu Asp Asp Glu Asp Gly Asp Gly
                  80                  85                  90

 Asp Gly Asp Gly Ala Thr Gly Lys Lys Lys Lys Lys Lys Lys Lys
                  95                 100                 105

 Lys Arg Gly Pro Lys Val Gln Thr Asp Pro Pro Ser Val Pro Ile
                 110                 115                 120

 Cys Asp Leu Tyr Pro Asn Gly Val Phe Pro Lys Gly Gln Glu Cys
                 125                 130                 135

 Glu Tyr Pro Pro Thr Gln Asp Gly Arg Thr Ala Ala Trp Arg Thr
                 140                 145                 150

 Thr Ser Glu Glu Lys Lys Ala Leu Asp Gln Ala Ser Glu Glu Ile
                 155                 160                 165

 Trp Asn Asp Phe Arg Glu Ala Ala Glu Ala His Arg Gln Val Arg
                 170                 175                 180

 Lys Tyr Val Met Ser Trp Ile Lys Pro Gly Met Thr Met Ile Glu
                 185                 190                 195

 Ile Cys Glu Lys Leu Glu Asp Cys Ser Arg Lys Leu Ile Lys Glu
                 200                 205                 210

 Asn Gly Leu Asn Ala Gly Leu Ala Phe Pro Thr Gly Cys Ser Leu
                 215                 220                 225

 Asn Asn Cys Ala Ala His Tyr Thr Pro Asn Ala Gly Asp Thr Thr
                 230                 235                 240

 Val Leu Gln Tyr Asp Asp Ile Cys Lys Ile Asp Phe Gly Thr His
                 245                 250                 255

 Ile Ser Gly Arg Ile Ile Asp Cys Ala Phe Thr Val Thr Phe Asn
                 260                 265                 270

 Pro Lys Tyr Asp Thr Leu Leu Lys Ala Val Lys Asp Ala Thr Asn
                 275                 280                 285

 Thr Gly Ile Lys Cys Ala Gly Ile Asp Val Arg Leu Cys Asp Val
                 290                 295                 300

 Gly Glu Ala Ile Gln Glu Val Met Glu Ser Tyr Glu Val Glu Ile
                 305                 310                 315

 Asp Gly Lys Thr Tyr Gln Val Lys Pro Ile Arg Asn Leu Asn Gly
                 320                 325                 330

 His Ser Ile Gly Gln Tyr Arg Ile His Ala Gly Lys Thr Val Pro
                 335                 340                 345

 Ile Val Lys Gly Gly Glu Ala Thr Arg Met Glu Glu Gly Glu Val
                 350                 355                 360

 Tyr Ala Ile Glu Thr Phe Gly Ser Thr Gly Lys Gly Val Val His
                 365                 370                 375

 Asp Asp Met Glu Cys Ser His Tyr Met Lys Asn Phe Asp Val Gly
                 380                 385                 390

 His Val Pro Ile Arg Leu Pro Arg Thr Lys His Leu Leu Asn Val
                 395                 400                 405

 Ile Asn Glu Asn Phe Gly Thr Leu Ala Phe Cys Arg Arg Trp Leu
                 410                 415                 420

 Asp Arg Leu Gly Glu Ser Lys Tyr Leu Met Ala Leu Lys Asn Leu
                 425                 430                 435

 Cys Asp Leu Gly Ile Val Asp Pro Tyr Pro Pro Leu Cys Asp Ile
                 440                 445                 450

 Lys Gly Ser Tyr Thr Ala Gln Phe Glu His Thr Ile Leu Leu Arg
                 455                 460                 465

 Pro Thr Cys Lys Glu Val Val Ser Arg Gly Asp Asp Tyr
                 470                 475

<210> 2129
<211> 5525
<212> DNA
<213> Homo sapien

<400> 2129
 gaagcgccgc cgccaccgcc gcctttgctg tcccccggcc tctagttccc 50

 cgcaggtggg aggtgggagc catgtcgaaa cggctccgga gcagcgaggt 100

 gtgcgctgac tgcagcgggc cggatccttc ctgggcatca gtaaataggg 150

 gaacgttttt atgtgatgag tgctgcagtg tccatcggag tctagggcgc 200

 catatctccc aagtgaggca tctgaaacac acaccgtggc ctccaacact 250

 gcttcagatg gttgagacct tgtataataa cggtgctaac tctatatggg 300

 agcattcttt gctggaccct gcgtctatta tgagtggaag acgtaaagct 350

 aatccacagg ataaagtaca tcccaataaa gcggaattca tcagagccaa 400

 gtatcagatg ttagcgttcg tccatcgctt gccctgccgg gatgacgata 450

 gtgtgactgc caaagatctt agcaagcaac tccattcgag cgtgagaaca 500

 gggaatcttg aaacctgttt gagactgtta tctttaggag cacaagccaa 550

 cttctttcat cctgaaaaag gaaacacccc actccatgtt gcctccaaag 600

 cagggcagat tttacaggct gaattattgg cagtatatgg agcagaccca 650

 ggcacacagg attctagtgg gaaaactccc gttgattatg caaggcaagg 700

 agggcaccat gagctggcag agcgcctcgt ggaaatacag tatgagctaa 750

 cggacagact agccttctat ctctgtggca ggaaaccaga tcacaaaaat 800

 ggacagcact ttataatacc tcaaatggca gacagcagcc tggatttgtc 850

 tgaattggca aaagctgcta agaagaaact tcaatctcta agtaatcatt 900

 tgtttgaaga acttgccatg gatgtgtacg atgaagttga caggcgagag 950

 acggatgcag tctggcttgc cacgcaaaac cacagcgccc tggtaaccga 1000

 gacaacggtc gtcccctttc ttccggtcaa tcctgagtac tcatcaacac 1050

 gaaatcaggg cagacagaag ttagctcggt tcaacgccca tgagtttgcc 1100

 acgctggtca ttgacattct cagtgacgcc aagaggagac agcagggcag 1150

 ttctctctcg ggttcaaaag acaatgtgga gctcatactg aaaaccatca 1200

 ataaccagca cagcgttgag agtcaagaca acgatcagcc cgactatgac 1250

 agcgtggcat cagacgaaga cacagatttg gaaaccactg caagcaaaac 1300

 aaaccggcag aagagcctag attcagattt atcagatgga ccagtcactg 1350

 tacaggaatt tatggaggtc aaaaacgctc tagtggcttc tgaggccaag 1400

 atacagcagc taatgaaggt gaataacaac ttgagtgacg agctgagaat 1450

 tatgcagaaa aagcttcaaa cactccagag tgaaaattcg aacctcagga 1500

 aacaggccac aaccaatgta tatcaggtgc aaactggttc tgagtacaca 1550

 gacacttcca accactcttc cttaaagaga cgtccgtctg cccggggcag 1600

 taggcccatg tccatgtacg agaccggatc aggtcagaaa ccatatctcc 1650

 caatgggaga agcgagccgc cccgaagaga gcaggatgag actccagccc 1700

 ttccccgcgc acatcgggag gagtgcactt gtgacctcct cttcatctct 1750

 gccttccttc ccctccacac tttcctggtc gagggacgaa agcgcccgaa 1800

 gggcatccag gctggagaag cagaacagca cacctgagag tgactacgac 1850

 aacactccca acgacatgga gccagatggc atggggtcaa gccgaaaggg 1900

 acggcaaaga agtatggtgt ggccagggga tggcttggta ccagacacag 1950

 cagaacccca tgtggcccca agccccactc tccctagcac cgaagatgtc 2000

 atcaggaaga ctgaacagat caccaaaaac atacaggagc tcttaagagc 2050

 agcccaagaa aataaacatg acagttatat tccctgctca gagaggatac 2100

 acgtagctgt tacagaaatg gcagcattat tccccaaaaa acccaagtct 2150

 gatatggtga ggacttccct tcgtttactg acgtccagtg cctaccgact 2200

 gcagtcagag tgcaagaaga ccctcccagg ggaccccggc tcacccacag 2250

 acgttcagct ggtcacgcag caggtcatcc agtgtgcgta cgacatcgcc 2300

 aaggctgcca agcagctggt taccatcacc accaaagaga acaacaactg 2350

 acaagggcag ggcaccgcct cctctgtttt ctaggcttta taaagtccaa 2400

 tttcaaattc agacgcagaa ctcttcagat ttctacaaaa agaaacattt 2450

 aatgacggtt taaaactttt taaaagaaaa ctcagtatta tttttgcatg 2500

 ttttctaacc aattttcaac tatttaaccc acttgcctta ttttgtgcct 2550

 atttgctggt ttagtttctg atgttcggtt gtgttgtcaa caactgttga 2600

 gttgatcaca tacatccaaa agtatagttt cattgtctaa agtttgtgaa 2650

 aacttttcca tcccttaaaa ctccctgcct atggctgaaa ctataaatga 2700

 aatttttcat aaaacatttt cttgagagag ttcagttaaa aaagaaaaaa 2750

 tcagcgtcat ttgttccctg ccaagcatcg tgcaataagt gaatttcctg 2800

 gcctacttca taatctctaa gtttggggta tctccaagca tgtatgtaga 2850

 gaaaggactt tgccgctttt taaaactagt gtcacagtct ctcttgggag 2900

 gaaacaatga attggttcat ttcttctcag tgttttaccc tgttacatgt 2950

 tctgttattt aatgttgtta tctcaagctc ctatctcttg atgttttctt 3000

 gtcatcttga aggctccatg gaatgagata aagcattgac ccaccacagg 3050

 acatctcatg aagccatgtt cagggtagga gctccacgca catcaccacc 3100

 cattgtcagg tgctctccct cacccctgta agccagacag tttgttcaaa 3150

 acctgcagca aagagaagca tcagtctaac aagccagaac tcattttgtg 3200

 ccacccattt aggtatcact accatgaact atagggaaaa gaaatcacct 3250

 actccctgac actgtgttgt acccttcatc caaaagtcag cttgcttctc 3300

 tgaccactta cagctttctc acatgagttg cttcacattt ttcatcatct 3350

 ttaaggactt cttataagga aagatgtatc gtatcgcagt catctgagtt 3400

 agtttctcct ccatcacctc atgagtactt aaaaattaga catcaacttt 3450

 caagagttcc ttagagagtg tgctctagct ggctgcctgc taccccaaag 3500

 ctctgaaaga gtaaggttga agtgctggaa catgctcaga ttgtttttta 3550

 gttactcaaa agccccttct tgttctgaat gtgaaagctc ttcccgttcc 3600

 tgcttactgc agccattctg tgtgtgtggt tcagaccctg gcctagggcc 3650

 ggtgatgtgg atgagtgaag ggagccaggt acacggcagc agggcagagg 3700

 agactatggg gagcccaccg cctacacagt aggggcagta gcccccagct 3750

 ccacgcctgt tgccatgtgg aaaagtgggc ctagggtggc cacagctttg 3800

 atttttcaag agacaagaaa cctagatgtt ttttggtgcc atctctccat 3850

 ttataaatgt tggcaaccaa tttgaacact ttcagagacc atgtgcaggt 3900

 gagctgtgtc ctctaggctg ccagctcaca gcccccaccc cagggccctg 3950

 taagctgtgc agtgtgaggg cctggcttcc ccggacacac ctggagcagc 4000

 ctctgagtct tacccgtaat ggagccggcc aaccctgtgt gttatgttgc 4050

 tgtcgctcct gtttttaacc atatgttctg tcccatagca gtcattcaca 4100

 catgtgaaga agacacaaga atcaaagtac aagttgcctc aatacatgct 4150

 aataactaag cttctatttt cacaggactg atcgatgcac acctttatag 4200

 cttgaccata tgctgtcatg aaagtagcac cccgacggtg cttgctttac 4250

 taagtcaccg tgtgtggatg cttttgtcgc attttgcttc actgtgagta 4300

 gcatgggaaa agggtccacg tctccaaaag actcttccac ttgtttgtcc 4350

 cacagcccta agtgccacat tgctgttgga tgctcccggg atgccttcta 4400

 gaagggggcc tcccacctta agttcaggcg ccatctgata gccttttctg 4450

 caggcttcat gtccttagct gaccctcctt tatcttgcaa acccctgccc 4500

 ctgctgtccc agggaggacg ggcttctgta gaggcttctg ggaaatgagc 4550

 tgtctgcagg aggtgaagca gtgttttcct tggaatgttt gaggacctgc 4600

 aatagaagat gttgccttta tggccctaga gaaagtcaag gaacatgggg 4650

 accaacaaag catttccagt tgtaagaata tgtcagaaga gtgctcggtt 4700

 agcccacggt gccaaaactc caaacaagtt ccccggtgga atgacgtggc 4750

 cattggaggg ctgcaggtcg tcctctctgt atgtgccccg cgcatttcct 4800

 tggcctcatc tgagatctgg tgtcagagtt ctctgctcct gttggcaaat 4850

 cgcaccttat ctgaacattt gttccagcca ccttttgcac atggattccg 4900

 taccttgcac tagcaatgtc taccttcagt aacgtcgttc tttttcaccc 4950

 tgtattctca atgatccctt cctccccata tgccaccctt cccccaaagc 5000

 tgatagggca gaggtgcact ttatgaaact ggcacttgac tgaacagaag 5050

 gaaacagctg tacctctaag ctcctttcac agaaatcgtc atctgccttg 5100

 gaatgcaaat agttcttatt tgccaaagaa cagtgaattg ggcccaaaga 5150

 tcaaacacag catttcatgt aatcagaatt ctaaacgcac aactcgggag 5200

 ctgtgcacgg cttctcaagt gattcagttg cagaaccaag agcaaaactc 5250

 gcctgttttt gtcctcaatg gcacccatga gctttccaat agtatagttt 5300

 tctttctttc cttgtcctgg ttgaaggtaa cgtgttccta gaaaagaaaa 5350

 tgctgcatag gaaaactgag atgcctttta ttccaacgtg tttgatccct 5400

 gtcactcatt attctgtact ttttattgta cattctattc ctgtaattat 5450

 tgtgcccttt aagtgttgta aaatcgtttt ggaatttgtg cctgctagtt 5500

 atgcaataaa caggctctac aagtg 5525

<210> 2130
<211> 759
<212> PRT
<213> Homo sapien

<400> 2130
 Met Ser Lys Arg Leu Arg Ser Ser Glu Val Cys Ala Asp Cys Ser
   1               5                  10                  15

 Gly Pro Asp Pro Ser Trp Ala Ser Val Asn Arg Gly Thr Phe Leu
                  20                  25                  30

 Cys Asp Glu Cys Cys Ser Val His Arg Ser Leu Gly Arg His Ile
                  35                  40                  45

 Ser Gln Val Arg His Leu Lys His Thr Pro Trp Pro Pro Thr Leu
                  50                  55                  60

 Leu Gln Met Val Glu Thr Leu Tyr Asn Asn Gly Ala Asn Ser Ile
                  65                  70                  75

 Trp Glu His Ser Leu Leu Asp Pro Ala Ser Ile Met Ser Gly Arg
                  80                  85                  90

 Arg Lys Ala Asn Pro Gln Asp Lys Val His Pro Asn Lys Ala Glu
                  95                 100                 105

 Phe Ile Arg Ala Lys Tyr Gln Met Leu Ala Phe Val His Arg Leu
                 110                 115                 120

 Pro Cys Arg Asp Asp Asp Ser Val Thr Ala Lys Asp Leu Ser Lys
                 125                 130                 135

 Gln Leu His Ser Ser Val Arg Thr Gly Asn Leu Glu Thr Cys Leu
                 140                 145                 150

 Arg Leu Leu Ser Leu Gly Ala Gln Ala Asn Phe Phe His Pro Glu
                 155                 160                 165

 Lys Gly Asn Thr Pro Leu His Val Ala Ser Lys Ala Gly Gln Ile
                 170                 175                 180

 Leu Gln Ala Glu Leu Leu Ala Val Tyr Gly Ala Asp Pro Gly Thr
                 185                 190                 195

 Gln Asp Ser Ser Gly Lys Thr Pro Val Asp Tyr Ala Arg Gln Gly
                 200                 205                 210

 Gly His His Glu Leu Ala Glu Arg Leu Val Glu Ile Gln Tyr Glu
                 215                 220                 225

 Leu Thr Asp Arg Leu Ala Phe Tyr Leu Cys Gly Arg Lys Pro Asp
                 230                 235                 240

 His Lys Asn Gly Gln His Phe Ile Ile Pro Gln Met Ala Asp Ser
                 245                 250                 255

 Ser Leu Asp Leu Ser Glu Leu Ala Lys Ala Ala Lys Lys Lys Leu
                 260                 265                 270

 Gln Ser Leu Ser Asn His Leu Phe Glu Glu Leu Ala Met Asp Val
                 275                 280                 285

 Tyr Asp Glu Val Asp Arg Arg Glu Thr Asp Ala Val Trp Leu Ala
                 290                 295                 300

 Thr Gln Asn His Ser Ala Leu Val Thr Glu Thr Thr Val Val Pro
                 305                 310                 315

 Phe Leu Pro Val Asn Pro Glu Tyr Ser Ser Thr Arg Asn Gln Gly
                 320                 325                 330

 Arg Gln Lys Leu Ala Arg Phe Asn Ala His Glu Phe Ala Thr Leu
                 335                 340                 345

 Val Ile Asp Ile Leu Ser Asp Ala Lys Arg Arg Gln Gln Gly Ser
                 350                 355                 360

 Ser Leu Ser Gly Ser Lys Asp Asn Val Glu Leu Ile Leu Lys Thr
                 365                 370                 375

 Ile Asn Asn Gln His Ser Val Glu Ser Gln Asp Asn Asp Gln Pro
                 380                 385                 390

 Asp Tyr Asp Ser Val Ala Ser Asp Glu Asp Thr Asp Leu Glu Thr
                 395                 400                 405

 Thr Ala Ser Lys Thr Asn Arg Gln Lys Ser Leu Asp Ser Asp Leu
                 410                 415                 420

 Ser Asp Gly Pro Val Thr Val Gln Glu Phe Met Glu Val Lys Asn
                 425                 430                 435

 Ala Leu Val Ala Ser Glu Ala Lys Ile Gln Gln Leu Met Lys Val
                 440                 445                 450

 Asn Asn Asn Leu Ser Asp Glu Leu Arg Ile Met Gln Lys Lys Leu
                 455                 460                 465

 Gln Thr Leu Gln Ser Glu Asn Ser Asn Leu Arg Lys Gln Ala Thr
                 470                 475                 480

 Thr Asn Val Tyr Gln Val Gln Thr Gly Ser Glu Tyr Thr Asp Thr
                 485                 490                 495

 Ser Asn His Ser Ser Leu Lys Arg Arg Pro Ser Ala Arg Gly Ser
                 500                 505                 510

 Arg Pro Met Ser Met Tyr Glu Thr Gly Ser Gly Gln Lys Pro Tyr
                 515                 520                 525

 Leu Pro Met Gly Glu Ala Ser Arg Pro Glu Glu Ser Arg Met Arg
                 530                 535                 540

 Leu Gln Pro Phe Pro Ala His Ile Gly Arg Ser Ala Leu Val Thr
                 545                 550                 555

 Ser Ser Ser Ser Leu Pro Ser Phe Pro Ser Thr Leu Ser Trp Ser
                 560                 565                 570

 Arg Asp Glu Ser Ala Arg Arg Ala Ser Arg Leu Glu Lys Gln Asn
                 575                 580                 585

 Ser Thr Pro Glu Ser Asp Tyr Asp Asn Thr Pro Asn Asp Met Glu
                 590                 595                 600

 Pro Asp Gly Met Gly Ser Ser Arg Lys Gly Arg Gln Arg Ser Met
                 605                 610                 615

 Val Trp Pro Gly Asp Gly Leu Val Pro Asp Thr Ala Glu Pro His
                 620                 625                 630

 Val Ala Pro Ser Pro Thr Leu Pro Ser Thr Glu Asp Val Ile Arg
                 635                 640                 645

 Lys Thr Glu Gln Ile Thr Lys Asn Ile Gln Glu Leu Leu Arg Ala
                 650                 655                 660

 Ala Gln Glu Asn Lys His Asp Ser Tyr Ile Pro Cys Ser Glu Arg
                 665                 670                 675

 Ile His Val Ala Val Thr Glu Met Ala Ala Leu Phe Pro Lys Lys
                 680                 685                 690

 Pro Lys Ser Asp Met Val Arg Thr Ser Leu Arg Leu Leu Thr Ser
                 695                 700                 705

 Ser Ala Tyr Arg Leu Gln Ser Glu Cys Lys Lys Thr Leu Pro Gly
                 710                 715                 720

 Asp Pro Gly Ser Pro Thr Asp Val Gln Leu Val Thr Gln Gln Val
                 725                 730                 735

 Ile Gln Cys Ala Tyr Asp Ile Ala Lys Ala Ala Lys Gln Leu Val
                 740                 745                 750

 Thr Ile Thr Thr Lys Glu Asn Asn Asn
                 755

<210> 2131
<211> 2041
<212> DNA
<213> Homo sapien

<400> 2131
 gccacttctt ctgggcccac gaggcagctg tcccatgctc tgctgagcac 50

 ggtggtgcca tgcctctgca actcctcctg ttgctgatcc tactgggccc 100

 tggcaacagc ttgcagctgt gggacacctg ggcagatgaa gccgagaaag 150

 ccttgggtcc cctgcttgcc cgggaccgga gacaggccac cgaatatgag 200

 tacctagatt atgatttcct gccagaaacg gagcctccag aaatgctgag 250

 gaacagcact gacaccactc ctctgactgg gcctggaacc cctgagtcta 300

 ccactgtgga gcctgctgca aggcgttcta ctggcctgga tgcaggaggg 350

 gcagtcacag agctgaccac ggagctggcc aacatgggga acctgtccac 400

 ggattcagca gctatggaga tacagaccac tcaaccagca gccacggagg 450

 cacagaccac tccactggca gccacagagg cacagacaac tcgactgacg 500

 gccacggagg cacagaccac tccactggca gccacagagg cacagaccac 550

 tccaccagca gccacggaag cacagaccac tcaacccaca ggcctggagg 600

 cacagaccac tgcaccagca gccatggagg cacagaccac tgcaccagca 650

 gccatggaag cacagaccac tccaccagca gccatggagg cacagaccac 700

 tcaaaccaca gccatggagg cacagaccac tgcaccagaa gccacggagg 750

 cacagaccac tcaacccaca gccacggagg cacagaccac tccactggca 800

 gccatggagg ccctgtccac agaacccagt gccacagagg ccctgtccat 850

 ggaacctact accaaaagag gtctgttcat acccttttct gtgtcctctg 900

 ttactcacaa gggcattccc atggcagcca gcaatttgtc cgtcaactac 950

 ccagtggggg ccccagacca catctctgtg aagcagtgcc tgctggccat 1000

 cctaatcttg gcgctggtgg ccactatctt cttcgtgtgc actgtggtgc 1050

 tggcggtccg cctctcccgc aagggccaca tgtaccccgt gcgtaattac 1100

 tcccccaccg agatggtctg catctcatcc ctgttgcctg atgggggtga 1150

 ggggccctct gccacagcca atgggggcct gtccaaggcc aagagcccgg 1200

 gcctgacgcc agagcccagg gaggaccgtg agggggatga cctcaccctg 1250

 cacagcttcc tcccttagct cactctgcca tctgttttgg caagacccca 1300

 cctccacggg ctctcctggg ccacccctga gtgcccagac cccaatccac 1350

 agctctgggc ttcctcggag acccctgggg atggggatct tcagggaagg 1400

 aactctggcc acccaaacag gacaagagca gcctggggcc aagcagacgg 1450

 gcaagtggag ccacctcttt cctccctccg cggatgaagc ccagccacat 1500

 ttcagccgag gtccaaggca ggaggccatt tacttgagac agattctctc 1550

 ctttttcctg tcccccatct tctctgggtc cctctaacat ctcccatggc 1600

 tctccccgct tctcctggtc actggagtct cctccccatg tacccaagga 1650

 agatggagct cccccatccc acacgcactg cactgccatt gtcttttggt 1700

 tgccatggtc accaaacagg aagtggacat tctaagggag gagtactgaa 1750

 gagtgacgga cttctgaggc tgtttcctgc tgctcctctg acttggggca 1800

 gcttgggtct tcttgggcac ctctctggga aaacccaggg tgaggttcag 1850

 cctgtgaggg ctgggatggg tttcgtgggc ccaaagggca gacctttctt 1900

 tgggactgtg tggaccaagg agcttccatc tagtgacaag tgacccccag 1950

 ctatcgcctc ttgccttccc ctgtggccac tttccagggt ggactctgtc 2000

 ttgttcactg cagtatccca actgcaggtc cagtgcaggc a 2041

<210> 2132
<211> 402
<212> PRT
<213> Homo sapien

<400> 2132
 Met Pro Leu Gln Leu Leu Leu Leu Leu Ile Leu Leu Gly Pro Gly
   1               5                  10                  15

 Asn Ser Leu Gln Leu Trp Asp Thr Trp Ala Asp Glu Ala Glu Lys
                  20                  25                  30

 Ala Leu Gly Pro Leu Leu Ala Arg Asp Arg Arg Gln Ala Thr Glu
                  35                  40                  45

 Tyr Glu Tyr Leu Asp Tyr Asp Phe Leu Pro Glu Thr Glu Pro Pro
                  50                  55                  60

 Glu Met Leu Arg Asn Ser Thr Asp Thr Thr Pro Leu Thr Gly Pro
                  65                  70                  75

 Gly Thr Pro Glu Ser Thr Thr Val Glu Pro Ala Ala Arg Arg Ser
                  80                  85                  90

 Thr Gly Leu Asp Ala Gly Gly Ala Val Thr Glu Leu Thr Thr Glu
                  95                 100                 105

 Leu Ala Asn Met Gly Asn Leu Ser Thr Asp Ser Ala Ala Met Glu
                 110                 115                 120

 Ile Gln Thr Thr Gln Pro Ala Ala Thr Glu Ala Gln Thr Thr Pro
                 125                 130                 135

 Leu Ala Ala Thr Glu Ala Gln Thr Thr Arg Leu Thr Ala Thr Glu
                 140                 145                 150

 Ala Gln Thr Thr Pro Leu Ala Ala Thr Glu Ala Gln Thr Thr Pro
                 155                 160                 165

 Pro Ala Ala Thr Glu Ala Gln Thr Thr Gln Pro Thr Gly Leu Glu
                 170                 175                 180

 Ala Gln Thr Thr Ala Pro Ala Ala Met Glu Ala Gln Thr Thr Ala
                 185                 190                 195

 Pro Ala Ala Met Glu Ala Gln Thr Thr Pro Pro Ala Ala Met Glu
                 200                 205                 210

 Ala Gln Thr Thr Gln Thr Thr Ala Met Glu Ala Gln Thr Thr Ala
                 215                 220                 225

 Pro Glu Ala Thr Glu Ala Gln Thr Thr Gln Pro Thr Ala Thr Glu
                 230                 235                 240

 Ala Gln Thr Thr Pro Leu Ala Ala Met Glu Ala Leu Ser Thr Glu
                 245                 250                 255

 Pro Ser Ala Thr Glu Ala Leu Ser Met Glu Pro Thr Thr Lys Arg
                 260                 265                 270

 Gly Leu Phe Ile Pro Phe Ser Val Ser Ser Val Thr His Lys Gly
                 275                 280                 285

 Ile Pro Met Ala Ala Ser Asn Leu Ser Val Asn Tyr Pro Val Gly
                 290                 295                 300

 Ala Pro Asp His Ile Ser Val Lys Gln Cys Leu Leu Ala Ile Leu
                 305                 310                 315

 Ile Leu Ala Leu Val Ala Thr Ile Phe Phe Val Cys Thr Val Val
                 320                 325                 330

 Leu Ala Val Arg Leu Ser Arg Lys Gly His Met Tyr Pro Val Arg
                 335                 340                 345

 Asn Tyr Ser Pro Thr Glu Met Val Cys Ile Ser Ser Leu Leu Pro
                 350                 355                 360

 Asp Gly Gly Glu Gly Pro Ser Ala Thr Ala Asn Gly Gly Leu Ser
                 365                 370                 375

 Lys Ala Lys Ser Pro Gly Leu Thr Pro Glu Pro Arg Glu Asp Arg
                 380                 385                 390

 Glu Gly Asp Asp Leu Thr Leu His Ser Phe Leu Pro
                 395                 400

<210> 2133
<211> 7785
<212> DNA
<213> Homo sapien

<400> 2133
 ctcactgtcc ctggaatctt caagggagtt actgcattac atcatcagaa 50

 acaaggcatt tctatattac tatggaaaga tttcgtctgg agaagaagtt 100

 acctggtcct gatgaagaag ctgttgtgga tcttggcaaa actagctcaa 150

 ctgtgaacac caagtttgaa aaagaagaac tagaaagtca tagagctgta 200

 tatattggtg ttcacgtccc gtttagtaaa gagagtcgtc ggcgtcatag 250

 gcatcgcgga cacaaacatc accaccggag gagaaaagat aaagaatcag 300

 ataaagaaga tggacgggaa tctccttctt atgatacacc atcccagaga 350

 gttcagttta tccttggtac tgaagatgat gatgaagaac atattcccca 400

 tgatctcttc acggaaatgg atgaactgtg ttacagagat ggagaagaat 450

 atgaatggaa agaaactgct agatggctga aatttgaaga ggatgttgaa 500

 gatggcggtg accgatggag taaaccttat gtggcaactc tctctttgca 550

 cagtcttttt gaactaagga gttgcatcct caatggaaca gtcatgctgg 600

 atatgagagc aagcactcta gatgaaatag cagatatggt attagacaac 650

 atgatagctt ctggccaatt agacgagtcc atacgagaga atgtcagaga 700

 agctcttctg aagagacatc atcatcagaa tgagaaaaga ttcaccagtc 750

 ggattcctct tgttcgatct tttgcagata taggcaagaa acattctgac 800

 cctcacttgc ttgaaaggaa tggggaaggc ctttcagcct cccgccactc 850

 tttgcgaaca ggtctgtctg cctcaaacct ttccttgaga ggagaatcac 900

 ctttatctct tcttctcggt catcttcttc cttcttcaag agctggaacc 950

 cctgcaggct caaggtgtac aaccccagta cccacccctc aaaacagtcc 1000

 tccttctagc cctagcatca gccgcctgac ctccagaagt tcccaaaaga 1050

 gtcagcgtca ggccccagaa ctactggttt cacctgccag tgatgatatt 1100

 cccacagtag taattcatcc gcctgaggaa gacttagaag cagcgctgaa 1150

 aggcgaggag cagaagaatg aggaaaatgt tgacttaact ccaggtattt 1200

 tggcctctcc ccagtctgct cctggaaact tggacaatag taaaagtgga 1250

 gaaattaaag gtaatggaag tggtggaagc agagaaaata gtactgttga 1300

 cttcagcaag gttgatatga atttcatgag aaaaattcct acgggtgctg 1350

 aggcatccaa cgtcctggtg ggcgaagtag actttttgga aaggccaata 1400

 attgcatttg tgagactggc tcctgctgtc ctccttacag ggttgactga 1450

 ggtccctgtt ccaaccaggt ttttgttttt gttattgggt ccagcgggca 1500

 aggcaccaca gtaccatgaa attggacgat caatagccac tctcatgaca 1550

 gatgagattt tccatgatgt agcttataaa gcaaaagaca gaaatgacct 1600

 cttatctgga attgatgaat ttttagatca agtaactgtc ctacctccag 1650

 gagagtggga tccttctata cgcatagaac caccaaaaag tgtcccttct 1700

 caggaaaaga gaaagattcc tgtgtttcac aatggatcta cccccacact 1750

 gggtgagact cctaaagagg ccgctcatca tgctgggcct gagctacaga 1800

 ggactggacg gctttttggt ggtttgatac ttgacatcaa aaggaaagca 1850

 ccttttttct tgagtgactt caaggatgca ttaagcctgc agtgcctggc 1900

 ctcgattctt ttcctatact gtgcctgtat gtctcctgta atcacttttg 1950

 gagggctgct tggagaagct acagaaggca gaataagtgc aatagagtct 2000

 ctttttggag catcattaac tgggattgcc tattcattgt ttgctgggca 2050

 acctctaaca atattgggga gcacaggtcc agttctagtg tttgaaaaaa 2100

 ttttatataa attctgcaga gattatcaac tttcttatct gtctttaaga 2150

 accagtattg gtctgtggac ttcttttttg tgcattgttt tggttgcaac 2200

 agatgcaagc agccttgtgt gttatattac tcgatttaca gaagaggctt 2250

 ttgcagccct tatttgcatc atattcatct acgaggcttt ggagaagctc 2300

 tttgatttag gagaaacata tgcatttaat atgcacaaca acttagataa 2350

 actgaccagc tactcatgtg tatgtactga acctccaaat cccagcaatg 2400

 aaactctagc acaatggaag aaagataata taacagcaca caatatttcc 2450

 tggagaaatc ttactgtttc tgaatgtaaa aaacttcgtg gtgtattctt 2500

 ggggtcagct tgtggtcatc atggacctta tattccagat gtgctctttt 2550

 ggtgtgtcat cttgtttttc acaacatttt ttctgtcttc attcctcaag 2600

 caatttaaga ccaagcgtta ctttcctacc aaggtgcgat cgacaatcag 2650

 tgattttgct gtatttctca caatagtaat aatggttaca attgactacc 2700

 ttgtaggagt tccatctcct aaacttcatg ttcctgaaaa atttgagcct 2750

 actcatccag agagagggtg gatcataagc ccactgggag ataatccttg 2800

 gtggacctta ttaatagctg ctattcctgc tttgctttgt accattctca 2850

 tctttatgga tcaacaaatc acagctgtaa ttataaacag aaaggaacac 2900

 aaattgaaga aaggagctgg ctatcacctt gatttgctca tggttggcgt 2950

 tatgttggga gtttgctctg tcatgggact tccatggttt gtggctgcaa 3000

 cagtgttgtc aataagtcat gtcaacagct taaaagttga atctgaatgt 3050

 tctgctccag gggaacaacc caagtttttg ggaattcgtg aacagcgggt 3100

 tacagggcta atgattttta ttctaatggg cctctctgtg ttcatgactt 3150

 cagtcctaaa gtttattcca atgcctgttc tgtatggtgt tttcctttat 3200

 atgggagttt cctcattaaa aggaatccag ttatttgacc gtataaaatt 3250

 atttggaatg cctgctaagc atcagcctga tttgatatac ctccgttatg 3300

 tgccgctctg gaaggtccat attttcacag tcattcagct tacttgtttg 3350

 gtccttttat gggtgataaa agtttcagct gctgcagtgg tttttcccat 3400

 gatggttctt gcattagtgt ttgtgcgcaa actcatggac ctgtgtttca 3450

 cgaagagaga acttagttgg cttgatgatc ttatgccaga aagtaagaaa 3500

 aagaaagaag atgacaaaaa gaaaaaagag aaagaggaag ctgaacggat 3550

 gcttcaagac gatgatgata ctgtgcacct tccatttgaa gggggaagtc 3600

 tcttgcaaat tccagtcaag gccctaaaat atagtcctga taaacctgtg 3650

 agtgtgaaaa taagttttga agatgaacca agaaagaaat acgtggatgc 3700

 tgaaacttca ttatagaatt gaaccaagag gcattataca tatagatata 3750

 tacatatgta atgtgtgcgt atcatgtcac tatatataag aatattgtat 3800

 gtcatgctgt ttatgtgtga ctaccgggtt tttaaaagta gtgtctggag 3850

 tttgtaatga gcaccgtgga gactatgtat ttaatgaaat gctctctttg 3900

 aagtgaggta catggttctt aactattcaa atatttattc tgttagaaaa 3950

 aaaaaatttt ctgttttgca atagaaggat gtggagaaat gctttcagtc 4000

 tacttttctt aaatctctgt tcatcagtgg caattcgtaa aaaccttaag 4050

 tgatactttg tttatatgtt tataattttt aggtgtttcc tgaaattttc 4100

 acatattatt tcacttttgt tagtgcttta tgggaagaat agggagtcta 4150

 taccagtgct gtgggaaaaa tggtaacatt tcagggcttc tctatttgtg 4200

 tttcatttct gtagatgtcc atcgtgtttc actaactggc gttttcttag 4250

 ccatagagat gactgtagaa caatagaaac tttaataatg atagttttta 4300

 acttttatgt ttaaattttt tttaaatctt aaaaccttca tatctaggta 4350

 tccattgtga cagacaagta aaattgcagg tgatttgata attaagcacc 4400

 cataccattt ataacttctg aatttaaaaa gttatacaat gccagtttgc 4450

 aatagttgat tttgatgcct ttgtagaata ttttttctga atccttatgc 4500

 tcttttaaag ccaatgattc ccactctgtt ctctgccttg tctctctttg 4550

 tcttaaaatg ctttagtttc catcaggttc aagttcttga ctattattct 4600

 cttataagta gtaggcgtaa ataatcagga gttagaattc tctcagaagg 4650

 gtctatgatc agtattactt tattaagaat tacctttcat tttctcttta 4700

 tgttattctt tcacttttgt agattacatt taatagcttg ttacctgtga 4750

 ttttatttta aaatatttat tttgatatga tgcttaaata ttatataaac 4800

 atttggaaaa gtaacaaata gagtaaattg ttaatgtaaa tagttggtgc 4850

 ttactttcat ttatgtttat tatcttaaag caattgatag attttacatc 4900

 tttgatataa agcactgcca tatttatatt ttaaaaggaa attagacatt 4950

 ttatatgtag ctcagattaa tgacattttt attttgtgta ttagtttttg 5000

 cttttctgag ctttttaaag tctaacaaat ctttttagtc atcttttata 5050

 tacttttagt tccacatgaa ataaatgttg ttaagcctgt aggactggat 5100

 gaatggggtt gtgaaactga tttgacaaga gaataattta caaaaatcaa 5150

 atgagtattg agaagccaca gaaatatcaa aaatggtgac atcactatta 5200

 ggatgaaaat tttatgaaat tccaatgctc cctttaacca tataattaaa 5250

 ttacaaaggt atacataatt aatctaataa aggatcatga ggaatgccaa 5300

 aagctgaaat tttagcaagt ctggtgtttt aaattcatta taaactattt 5350

 attaactaat gtaatgtcct cctctaagac catattgtaa gagtcttgtt 5400

 aaaatgatgg attcaacttc tgcctcggat gagaggttgg aaatgtagct 5450

 gcttttcttt agaaaatatg tagctgtcat catttggtac tgcctaaaaa 5500

 gagttagact ctattggcaa ttgatagagt attacccacg gtgcttatta 5550

 ttgtttatga gcttccattg taatgattcc tttttatttg tagcagcata 5600

 attatttcca aagaccccag tatttgctgc tatttttaaa actcccctga 5650

 tgtacctgaa caagaggatt tcctcacatc atttccttgt gtctggacat 5700

 caggggtaac aactgtactt actttacagg aagaaatttt aaaactgaaa 5750

 actacctggg atcatagtgt ttctgtgatt ttatttaatt gtgtatagta 5800

 attatccagt gccagaaaaa ccgtcacttg caaaatactt tgcactcaaa 5850

 atgtttttac aatgcttcta aatgttactg gtttctgctt tcttttgact 5900

 acttgactga caaaatgatc tgactactcc atttaagagc aaaggtaact 5950

 catgtttaag taattaactg cttgttttaa gtgattatat ttcttccact 6000

 gtttttgaaa aataatcaaa gatagcattc attgagagac agtgacagat 6050

 ataatttact acatatattg atttttaaat aaagttgcct taaataagtg 6100

 tatgtaagca gtagtagttg ctatgtactg atttacctca aggtgcaaaa 6150

 taattaaacc tgtacatatt ccatttacaa aataaattca gccctgcact 6200

 ttctttagat gccttgattt ccagaatgga gcttagtgct actgaatacc 6250

 ctggccacag agccacctca ggatattctt ttctccaccc tagtttattt 6300

 atttatagat atctgtttac aaagtctgta gtaaatcctg atgctgacca 6350

 tctgaaatgt actttttttc tgaatgctgt ttcaatctaa aatagcagct 6400

 tttgagaaaa caatgatgta aattccttat gataaaagga tgattctata 6450

 tattctttaa tgatattaaa tatgccgaag ccaagcacac agtctttcta 6500

 aagtgtgtgt atgtttgtgt gaatgtgaat gatactgatc ttatatctgt 6550

 taaaagttgt tttaaaaagc tgtggcatcc cattgttcat atttgccaag 6600

 tcttctgtaa agatgtctag gacgaaatat tttatgtgct aatgcatgta 6650

 tttgtaaacc agatttgttt accactcaaa attaacttgt tttcttcatc 6700

 caaaaaagtt tatgtcttcc acgtacttaa attttctgtg tgggtataat 6750

 atagctttct aatttttttc tttcacaaag gcaggttcaa aattctgttg 6800

 aaagaaaaat gctttctgaa actgaggtat aacaccagag cttgctgttt 6850

 aaaggattat atgatgtaca tcagttctat aaatgtgctc agcagtttaa 6900

 catgtgaatc ctgttttaaa gtgctcagat ttcaactgtg taagccattg 6950

 atataacgct gtaattaaaa atgtttatat gaaataactt aatgttttaa 7000

 atttatttat gtagatcaca tcatttttat cagtatgcag tgcaaatatg 7050

 tgaaatgtct tttggtttat tccaacaatt atttatttta gaaagtaagt 7100

 ttaaagactt taaggacatt caaagtttaa aatagtgttc aaattgcaaa 7150

 atttggcaat cttcatataa attggtttct tttctaactt ttcaaaaact 7200

 aacattaaat gtcaattata ggaaaacata gttggaaatg taatcatccc 7250

 aaagatcatt tttaaaatga aatttaatta gcacatattg aacatttgac 7300

 ttaattgtta aaccccagtt ttgttttgtt tttttaatca gatttttgca 7350

 cactgattag tttttgtgtt gtggcttttg ttgctttatt attcaaggtt 7400

 tttttttttc tttccccatg ggggagattg tcttccaatg tttaactacg 7450

 tttaaataaa taaaaattga attttattgt tcatttatat aaaatctgat 7500

 accttgatgt aatttcacaa tacagttcca atttttatgg cttttataat 7550

 tacaatgata ttttcttcta taataaaatc caaagtaaac atttaaattg 7600

 tagaactgat atttttcatt tatatgaagt ataagcctct actgggtcta 7650

 tattgtgaat catcctgcct ttcaaatttg tttcataatt gttagatgaa 7700

 aactattttt ttggagatgt tactgaagtt gattgagcaa taaaagtcta 7750

 cttaattaaa aaaaaaaaaa aaaaaaaaaa aaaaa 7785

<210> 2134
<211> 1214
<212> PRT
<213> Homo sapien

<400> 2134
 Met Glu Arg Phe Arg Leu Glu Lys Lys Leu Pro Gly Pro Asp Glu
   1               5                  10                  15

 Glu Ala Val Val Asp Leu Gly Lys Thr Ser Ser Thr Val Asn Thr
                  20                  25                  30

 Lys Phe Glu Lys Glu Glu Leu Glu Ser His Arg Ala Val Tyr Ile
                  35                  40                  45

 Gly Val His Val Pro Phe Ser Lys Glu Ser Arg Arg Arg His Arg
                  50                  55                  60

 His Arg Gly His Lys His His His Arg Arg Arg Lys Asp Lys Glu
                  65                  70                  75

 Ser Asp Lys Glu Asp Gly Arg Glu Ser Pro Ser Tyr Asp Thr Pro
                  80                  85                  90

 Ser Gln Arg Val Gln Phe Ile Leu Gly Thr Glu Asp Asp Asp Glu
                  95                 100                 105

 Glu His Ile Pro His Asp Leu Phe Thr Glu Met Asp Glu Leu Cys
                 110                 115                 120

 Tyr Arg Asp Gly Glu Glu Tyr Glu Trp Lys Glu Thr Ala Arg Trp
                 125                 130                 135

 Leu Lys Phe Glu Glu Asp Val Glu Asp Gly Gly Asp Arg Trp Ser
                 140                 145                 150

 Lys Pro Tyr Val Ala Thr Leu Ser Leu His Ser Leu Phe Glu Leu
                 155                 160                 165

 Arg Ser Cys Ile Leu Asn Gly Thr Val Met Leu Asp Met Arg Ala
                 170                 175                 180

 Ser Thr Leu Asp Glu Ile Ala Asp Met Val Leu Asp Asn Met Ile
                 185                 190                 195

 Ala Ser Gly Gln Leu Asp Glu Ser Ile Arg Glu Asn Val Arg Glu
                 200                 205                 210

 Ala Leu Leu Lys Arg His His His Gln Asn Glu Lys Arg Phe Thr
                 215                 220                 225

 Ser Arg Ile Pro Leu Val Arg Ser Phe Ala Asp Ile Gly Lys Lys
                 230                 235                 240

 His Ser Asp Pro His Leu Leu Glu Arg Asn Gly Glu Gly Leu Ser
                 245                 250                 255

 Ala Ser Arg His Ser Leu Arg Thr Gly Leu Ser Ala Ser Asn Leu
                 260                 265                 270

 Ser Leu Arg Gly Glu Ser Pro Leu Ser Leu Leu Leu Gly His Leu
                 275                 280                 285

 Leu Pro Ser Ser Arg Ala Gly Thr Pro Ala Gly Ser Arg Cys Thr
                 290                 295                 300

 Thr Pro Val Pro Thr Pro Gln Asn Ser Pro Pro Ser Ser Pro Ser
                 305                 310                 315

 Ile Ser Arg Leu Thr Ser Arg Ser Ser Gln Lys Ser Gln Arg Gln
                 320                 325                 330

 Ala Pro Glu Leu Leu Val Ser Pro Ala Ser Asp Asp Ile Pro Thr
                 335                 340                 345

 Val Val Ile His Pro Pro Glu Glu Asp Leu Glu Ala Ala Leu Lys
                 350                 355                 360

 Gly Glu Glu Gln Lys Asn Glu Glu Asn Val Asp Leu Thr Pro Gly
                 365                 370                 375

 Ile Leu Ala Ser Pro Gln Ser Ala Pro Gly Asn Leu Asp Asn Ser
                 380                 385                 390

 Lys Ser Gly Glu Ile Lys Gly Asn Gly Ser Gly Gly Ser Arg Glu
                 395                 400                 405

 Asn Ser Thr Val Asp Phe Ser Lys Val Asp Met Asn Phe Met Arg
                 410                 415                 420

 Lys Ile Pro Thr Gly Ala Glu Ala Ser Asn Val Leu Val Gly Glu
                 425                 430                 435

 Val Asp Phe Leu Glu Arg Pro Ile Ile Ala Phe Val Arg Leu Ala
                 440                 445                 450

 Pro Ala Val Leu Leu Thr Gly Leu Thr Glu Val Pro Val Pro Thr
                 455                 460                 465

 Arg Phe Leu Phe Leu Leu Leu Gly Pro Ala Gly Lys Ala Pro Gln
                 470                 475                 480

 Tyr His Glu Ile Gly Arg Ser Ile Ala Thr Leu Met Thr Asp Glu
                 485                 490                 495

 Ile Phe His Asp Val Ala Tyr Lys Ala Lys Asp Arg Asn Asp Leu
                 500                 505                 510

 Leu Ser Gly Ile Asp Glu Phe Leu Asp Gln Val Thr Val Leu Pro
                 515                 520                 525

 Pro Gly Glu Trp Asp Pro Ser Ile Arg Ile Glu Pro Pro Lys Ser
                 530                 535                 540

 Val Pro Ser Gln Glu Lys Arg Lys Ile Pro Val Phe His Asn Gly
                 545                 550                 555

 Ser Thr Pro Thr Leu Gly Glu Thr Pro Lys Glu Ala Ala His His
                 560                 565                 570

 Ala Gly Pro Glu Leu Gln Arg Thr Gly Arg Leu Phe Gly Gly Leu
                 575                 580                 585

 Ile Leu Asp Ile Lys Arg Lys Ala Pro Phe Phe Leu Ser Asp Phe
                 590                 595                 600

 Lys Asp Ala Leu Ser Leu Gln Cys Leu Ala Ser Ile Leu Phe Leu
                 605                 610                 615

 Tyr Cys Ala Cys Met Ser Pro Val Ile Thr Phe Gly Gly Leu Leu
                 620                 625                 630

 Gly Glu Ala Thr Glu Gly Arg Ile Ser Ala Ile Glu Ser Leu Phe
                 635                 640                 645

 Gly Ala Ser Leu Thr Gly Ile Ala Tyr Ser Leu Phe Ala Gly Gln
                 650                 655                 660

 Pro Leu Thr Ile Leu Gly Ser Thr Gly Pro Val Leu Val Phe Glu
                 665                 670                 675

 Lys Ile Leu Tyr Lys Phe Cys Arg Asp Tyr Gln Leu Ser Tyr Leu
                 680                 685                 690

 Ser Leu Arg Thr Ser Ile Gly Leu Trp Thr Ser Phe Leu Cys Ile
                 695                 700                 705

 Val Leu Val Ala Thr Asp Ala Ser Ser Leu Val Cys Tyr Ile Thr
                 710                 715                 720

 Arg Phe Thr Glu Glu Ala Phe Ala Ala Leu Ile Cys Ile Ile Phe
                 725                 730                 735

 Ile Tyr Glu Ala Leu Glu Lys Leu Phe Asp Leu Gly Glu Thr Tyr
                 740                 745                 750

 Ala Phe Asn Met His Asn Asn Leu Asp Lys Leu Thr Ser Tyr Ser
                 755                 760                 765

 Cys Val Cys Thr Glu Pro Pro Asn Pro Ser Asn Glu Thr Leu Ala
                 770                 775                 780

 Gln Trp Lys Lys Asp Asn Ile Thr Ala His Asn Ile Ser Trp Arg
                 785                 790                 795

 Asn Leu Thr Val Ser Glu Cys Lys Lys Leu Arg Gly Val Phe Leu
                 800                 805                 810

 Gly Ser Ala Cys Gly His His Gly Pro Tyr Ile Pro Asp Val Leu
                 815                 820                 825

 Phe Trp Cys Val Ile Leu Phe Phe Thr Thr Phe Phe Leu Ser Ser
                 830                 835                 840

 Phe Leu Lys Gln Phe Lys Thr Lys Arg Tyr Phe Pro Thr Lys Val
                 845                 850                 855

 Arg Ser Thr Ile Ser Asp Phe Ala Val Phe Leu Thr Ile Val Ile
                 860                 865                 870

 Met Val Thr Ile Asp Tyr Leu Val Gly Val Pro Ser Pro Lys Leu
                 875                 880                 885

 His Val Pro Glu Lys Phe Glu Pro Thr His Pro Glu Arg Gly Trp
                 890                 895                 900

 Ile Ile Ser Pro Leu Gly Asp Asn Pro Trp Trp Thr Leu Leu Ile
                 905                 910                 915

 Ala Ala Ile Pro Ala Leu Leu Cys Thr Ile Leu Ile Phe Met Asp
                 920                 925                 930

 Gln Gln Ile Thr Ala Val Ile Ile Asn Arg Lys Glu His Lys Leu
                 935                 940                 945

 Lys Lys Gly Ala Gly Tyr His Leu Asp Leu Leu Met Val Gly Val
                 950                 955                 960

 Met Leu Gly Val Cys Ser Val Met Gly Leu Pro Trp Phe Val Ala
                 965                 970                 975

 Ala Thr Val Leu Ser Ile Ser His Val Asn Ser Leu Lys Val Glu
                 980                 985                 990

 Ser Glu Cys Ser Ala Pro Gly Glu Gln Pro Lys Phe Leu Gly Ile
                 995                1000                1005

 Arg Glu Gln Arg Val Thr Gly Leu Met Ile Phe Ile Leu Met Gly
                1010                1015                1020

 Leu Ser Val Phe Met Thr Ser Val Leu Lys Phe Ile Pro Met Pro
                1025                1030                1035

 Val Leu Tyr Gly Val Phe Leu Tyr Met Gly Val Ser Ser Leu Lys
                1040                1045                1050

 Gly Ile Gln Leu Phe Asp Arg Ile Lys Leu Phe Gly Met Pro Ala
                1055                1060                1065

 Lys His Gln Pro Asp Leu Ile Tyr Leu Arg Tyr Val Pro Leu Trp
                1070                1075                1080

 Lys Val His Ile Phe Thr Val Ile Gln Leu Thr Cys Leu Val Leu
                1085                1090                1095

 Leu Trp Val Ile Lys Val Ser Ala Ala Ala Val Val Phe Pro Met
                1100                1105                1110

 Met Val Leu Ala Leu Val Phe Val Arg Lys Leu Met Asp Leu Cys
                1115                1120                1125

 Phe Thr Lys Arg Glu Leu Ser Trp Leu Asp Asp Leu Met Pro Glu
                1130                1135                1140

 Ser Lys Lys Lys Lys Glu Asp Asp Lys Lys Lys Lys Glu Lys Glu
                1145                1150                1155

 Glu Ala Glu Arg Met Leu Gln Asp Asp Asp Asp Thr Val His Leu
                1160                1165                1170

 Pro Phe Glu Gly Gly Ser Leu Leu Gln Ile Pro Val Lys Ala Leu
                1175                1180                1185

 Lys Tyr Ser Pro Asp Lys Pro Val Ser Val Lys Ile Ser Phe Glu
                1190                1195                1200

 Asp Glu Pro Arg Lys Lys Tyr Val Asp Ala Glu Thr Ser Leu
                1205                1210

<210> 2135
<211> 4649
<212> DNA
<213> Homo sapien

<400> 2135
 gaggagcggc tccggccgcc gcgcctgacc cttgtccggg gtcttccgca 50

 cagtgggctg agggccatgt cagttttctg ccacctacag gatagaccat 100

 gaagctgaag gaacttgagc ggccagctgt ccaggcatgg agcccagcca 150

 gccaataccc tttgtatctg gccacaggaa catctgccca acagctagat 200

 tcctccttca gcacaaatgg cacattggaa atatttgagg ttgatttcag 250

 ggacccttct ctggacttga aacacagagg agtcctttct gccttgagca 300

 ggtttcacaa gctggtctgg gggagctttg gcagtgggct tctggaaagc 350

 tccggggtta ttgttggcgg cggggacaat ggcatgctta ttctatacaa 400

 tgtgacccac atcctgtctt cggggaagga gcctgtgatt gctcagaaac 450

 agaagcacac gggggctgtc agagccctcg acttgaatcc tttccagggc 500

 aacctcctgg cttcaggggc cagcgattct gaaatcttca tttgggatct 550

 gaataacttg aatgtgccaa tgaccctggg atccaagtca cagcagcctc 600

 cagaggacat caaggcactg tcttggaacc ggcaagccca acacattctg 650

 tcttctgctc accccagtgg caaggcagtt gtgtgggatc tcaggaagaa 700

 tgaacctatc atcaaagtca gtgatcacag caacaggatg cactgctcag 750

 gcctggcctg gcatcctgac atagccaccc agttagtgct gtgctcagag 800

 gatgatcgac ttcccgtgat tcagctgtgg gacttgcgct ttgcctcctc 850

 gcccttgaag gtgctggaga gccacagcag ggggatcttg tcagtgtcat 900

 ggagccaggc tgatgctgag ctgctgctca ctagtgctaa ggacagccag 950

 atcttgtgcc ggaacctggg gagcagtgag gtggtatata agctaccaac 1000

 acagagcagc tggtgctttg atgtgcagtg gtgccctcgg gacccttcag 1050

 tgttctctgc tgcctccttc aacggctgga tcagtttgta ctctgtgatg 1100

 ggtaggagct gggaagtcca gcatatgaga caggctgaca agatctcctc 1150

 ttccttcagc aaaggccagc ctctcccacc actgcaggtg ccagagcaag 1200

 tggcacaagc accactgata cctcccctga aaaaaccccc caaatggatt 1250

 agaagaccaa caggtgtttc atttgctttt ggagggaagc tggttacttt 1300

 tggcctcccc agcacccctg cccatctggt gccacagcct tgcccccgcc 1350

 tagtcttcat cagtcaagtc accacagaat ctgaattcct gatgcgatca 1400

 gctgagctgc aggaggcctt gggatcagga aatctactga attactgtca 1450

 gaacaagagc cagcaagctt tactgcaaag tgaaaagatg ctgtggcagt 1500

 tcctgaaggt gaccttagag caagactcca gaatgaaatt cctaaagctt 1550

 ttaggataca gtaaagatga gcttcagaag aaggtggcca catggttgaa 1600

 gagtgacgtg gggctaggtg agagtcctca gcccaaggga aatgacctca 1650

 acagtgacag acaacaggcc ttctgcagcc aggcctccaa acacaccaca 1700

 aaggaagcct ctgcttcctc agccttcttt gatgagctgg tccctcagaa 1750

 catgactcct tgggagatcc ccatcacaaa agatattgat ggactcctaa 1800

 gccaggctct cctgcttggg gaactgggtc cggccgtgga gctgtgtctg 1850

 aaggaggagc gctttgctga tgccattatc ctggcccagg ctgggggtac 1900

 agatctgctg aagcaaacac aggagcgcta cttggccaag aagaaaacca 1950

 aaatctcctc gcttctagcc tgtgttgtgc aaaagaattg gaaggatgtg 2000

 gtgtgtacct gtagcctgaa gaactggaga gaggcactgg ctttgctact 2050

 gacatactca ggcacagaga aatttcccga gctctgtgac atgctgggaa 2100

 ctcgcatgga acaggagggc agcagggcac taacctccga agccagactc 2150

 tgttatgtgt gctcagggag tgtggagcgg ctggtggagt gctgggcaaa 2200

 atgccaccag gctttgtccc ccatggctct gcaggacctg atggagaagg 2250

 tgatggttct taacaggagc ttggagcaac tgcggggtcc tcatggggtg 2300

 agcccaggcc ctgccacaac ctacagggtc actcagtatg ccaacctcct 2350

 ggcagcccag ggcagcctgg ccactgccat gagctttcta cccagggact 2400

 gtgctcagcc accagttcag cagctaagag atcggctttt tcatgctcaa 2450

 ggttctgctg tcttgggcca acagtctccc cctttcccct tcccccggat 2500

 tgttgtggga gctaccctcc actctaaaga gacatcatct tacagattgg 2550

 gatcccagcc ttctcaccag gtcccaactc catctccaag gccaagggtt 2600

 ttcacccctc agtcatcacc agcgatgccc ttggcacctt cccatcctag 2650

 cccttatcag ggtcccagga cacagaatat aagtgactac agggcacctg 2700

 ggccccaggc catccagcct ttgcctttga gccctggggt aaggcctgct 2750

 tcatctcagc cacagctatt aggagggcaa agggtgcaag ttcctaaccc 2800

 ggtgggattc cctgggacat ggcctcttcc tggttcccct ctacccatgg 2850

 catgcccagg catcatgcga cctggctcta cctccctgcc tgagactcct 2900

 agactgttcc ctctgcttcc tctgagacca ctaggtcccg gccgcatggt 2950

 ctcccacacc ccagcccctc ctgcaagctt ccctgtgcca taccttccag 3000

 gggacccagg tgccccatgc tctagtgtcc tcccaaccac tggcatcttg 3050

 actcctcacc caggacctca agattcctgg aaagaagccc cagcccccag 3100

 gggaaacctc cagaggaaca agctgccaga gacatttatg cccccagcac 3150

 caattactgc tccagttatg agcctcaccc ctgagctaca agggattctt 3200

 ccctcacagc cccctgtctc cagtgtgagt catgctcccc caggagttcc 3250

 aggagaactc agcctgcagc ttcagcacct gccacctgag aagatggaaa 3300

 ggaaggagct gcccccagag catcagtcct tgaagagcag ctttgaggcg 3350

 cttctccaac gctgctccct gtctgcaact gacttaaaga caaaaaggaa 3400

 gctggaagag gcagcccagc gtctggagta tctatatgag aagctctgtg 3450

 aggggacact ctcacctcat gtcgtggctg ggctccatga ggttgcccga 3500

 tgtgtggatg caggaagctt tgagcagggc cttgcagtgc atgcccaggt 3550

 ggcgggctgt agcagcttca gcgaggtgtc cagcttcatg cctatcctga 3600

 aggctgtcct catcatcgct cataagctgc tggtctaaac caggcagcct 3650

 ctcttgctag gaggccactt ctgctgttac ataactcctc cctgcagaag 3700

 aggggacttc tgcaacagat tctgtttctt tttcccgact cttttccttg 3750

 ctgccaggta tgtgatgctg taggcttggc tccaaaccag ctgagtgcct 3800

 gctttttact cctttatgtc tggccttcta ggatctgtcc aagacactct 3850

 caggcctgga ggcagggcat agaatcagtt cttcactctc cctaatacta 3900

 cactctgtaa ggacctgggg caggatatct tctcccccag ggatcttcta 3950

 tttaagtggc ttctgagagg gtgaacagga ttgttacttt taagcctacc 4000

 tctgctgtga cccatcatgt gggtcttttg tttctccctt ctgtggttta 4050

 tgagcctgcc cttacctttt ccctgcctct gacttggtat ttccaggtcc 4100

 gtatttctct gtagcccagg gtctggggta gagctgactg ctgttcaccc 4150

 tttgaacaac tcatggacgt gagggatggg tgctgagcag aaccaagaga 4200

 ggaaactttg gcgctgttaa aatggaattt ctcatctgcc ggcattatta 4250

 agggtgggct aggttggatg gaaggtgaaa gggatgaact gccttttgct 4300

 ggaagctgtc ttaggctgtg agacaggagc aggggaacca cagcctatgg 4350

 ggaactgccc ttgactccac ctatgttgga gccttagccc aaggccattc 4400

 cttctgtgat gataaagccc agttctggaa ttggagccat attaaggaat 4450

 gattctcttc cagcgctgct cctcaagggt tgggggtcct tctccctcgc 4500

 agccaccaca tgtctcaggg ctaccttctc cgattggatt tgcatttgtg 4550

 gcactgtctt tgatgcagtg atgtacttaa tggtgcaata aagctgcttc 4600

 gatttggtaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 4649

<210> 2136
<211> 1179
<212> PRT
<213> Homo sapien

<400> 2136
 Met Lys Leu Lys Glu Leu Glu Arg Pro Ala Val Gln Ala Trp Ser
   1               5                  10                  15

 Pro Ala Ser Gln Tyr Pro Leu Tyr Leu Ala Thr Gly Thr Ser Ala
                  20                  25                  30

 Gln Gln Leu Asp Ser Ser Phe Ser Thr Asn Gly Thr Leu Glu Ile
                  35                  40                  45

 Phe Glu Val Asp Phe Arg Asp Pro Ser Leu Asp Leu Lys His Arg
                  50                  55                  60

 Gly Val Leu Ser Ala Leu Ser Arg Phe His Lys Leu Val Trp Gly
                  65                  70                  75

 Ser Phe Gly Ser Gly Leu Leu Glu Ser Ser Gly Val Ile Val Gly
                  80                  85                  90

 Gly Gly Asp Asn Gly Met Leu Ile Leu Tyr Asn Val Thr His Ile
                  95                 100                 105

 Leu Ser Ser Gly Lys Glu Pro Val Ile Ala Gln Lys Gln Lys His
                 110                 115                 120

 Thr Gly Ala Val Arg Ala Leu Asp Leu Asn Pro Phe Gln Gly Asn
                 125                 130                 135

 Leu Leu Ala Ser Gly Ala Ser Asp Ser Glu Ile Phe Ile Trp Asp
                 140                 145                 150

 Leu Asn Asn Leu Asn Val Pro Met Thr Leu Gly Ser Lys Ser Gln
                 155                 160                 165

 Gln Pro Pro Glu Asp Ile Lys Ala Leu Ser Trp Asn Arg Gln Ala
                 170                 175                 180

 Gln His Ile Leu Ser Ser Ala His Pro Ser Gly Lys Ala Val Val
                 185                 190                 195

 Trp Asp Leu Arg Lys Asn Glu Pro Ile Ile Lys Val Ser Asp His
                 200                 205                 210

 Ser Asn Arg Met His Cys Ser Gly Leu Ala Trp His Pro Asp Ile
                 215                 220                 225

 Ala Thr Gln Leu Val Leu Cys Ser Glu Asp Asp Arg Leu Pro Val
                 230                 235                 240

 Ile Gln Leu Trp Asp Leu Arg Phe Ala Ser Ser Pro Leu Lys Val
                 245                 250                 255

 Leu Glu Ser His Ser Arg Gly Ile Leu Ser Val Ser Trp Ser Gln
                 260                 265                 270

 Ala Asp Ala Glu Leu Leu Leu Thr Ser Ala Lys Asp Ser Gln Ile
                 275                 280                 285

 Leu Cys Arg Asn Leu Gly Ser Ser Glu Val Val Tyr Lys Leu Pro
                 290                 295                 300

 Thr Gln Ser Ser Trp Cys Phe Asp Val Gln Trp Cys Pro Arg Asp
                 305                 310                 315

 Pro Ser Val Phe Ser Ala Ala Ser Phe Asn Gly Trp Ile Ser Leu
                 320                 325                 330

 Tyr Ser Val Met Gly Arg Ser Trp Glu Val Gln His Met Arg Gln
                 335                 340                 345

 Ala Asp Lys Ile Ser Ser Ser Phe Ser Lys Gly Gln Pro Leu Pro
                 350                 355                 360

 Pro Leu Gln Val Pro Glu Gln Val Ala Gln Ala Pro Leu Ile Pro
                 365                 370                 375

 Pro Leu Lys Lys Pro Pro Lys Trp Ile Arg Arg Pro Thr Gly Val
                 380                 385                 390

 Ser Phe Ala Phe Gly Gly Lys Leu Val Thr Phe Gly Leu Pro Ser
                 395                 400                 405

 Thr Pro Ala His Leu Val Pro Gln Pro Cys Pro Arg Leu Val Phe
                 410                 415                 420

 Ile Ser Gln Val Thr Thr Glu Ser Glu Phe Leu Met Arg Ser Ala
                 425                 430                 435

 Glu Leu Gln Glu Ala Leu Gly Ser Gly Asn Leu Leu Asn Tyr Cys
                 440                 445                 450

 Gln Asn Lys Ser Gln Gln Ala Leu Leu Gln Ser Glu Lys Met Leu
                 455                 460                 465

 Trp Gln Phe Leu Lys Val Thr Leu Glu Gln Asp Ser Arg Met Lys
                 470                 475                 480

 Phe Leu Lys Leu Leu Gly Tyr Ser Lys Asp Glu Leu Gln Lys Lys
                 485                 490                 495

 Val Ala Thr Trp Leu Lys Ser Asp Val Gly Leu Gly Glu Ser Pro
                 500                 505                 510

 Gln Pro Lys Gly Asn Asp Leu Asn Ser Asp Arg Gln Gln Ala Phe
                 515                 520                 525

 Cys Ser Gln Ala Ser Lys His Thr Thr Lys Glu Ala Ser Ala Ser
                 530                 535                 540

 Ser Ala Phe Phe Asp Glu Leu Val Pro Gln Asn Met Thr Pro Trp
                 545                 550                 555

 Glu Ile Pro Ile Thr Lys Asp Ile Asp Gly Leu Leu Ser Gln Ala
                 560                 565                 570

 Leu Leu Leu Gly Glu Leu Gly Pro Ala Val Glu Leu Cys Leu Lys
                 575                 580                 585

 Glu Glu Arg Phe Ala Asp Ala Ile Ile Leu Ala Gln Ala Gly Gly
                 590                 595                 600

 Thr Asp Leu Leu Lys Gln Thr Gln Glu Arg Tyr Leu Ala Lys Lys
                 605                 610                 615

 Lys Thr Lys Ile Ser Ser Leu Leu Ala Cys Val Val Gln Lys Asn
                 620                 625                 630

 Trp Lys Asp Val Val Cys Thr Cys Ser Leu Lys Asn Trp Arg Glu
                 635                 640                 645

 Ala Leu Ala Leu Leu Leu Thr Tyr Ser Gly Thr Glu Lys Phe Pro
                 650                 655                 660

 Glu Leu Cys Asp Met Leu Gly Thr Arg Met Glu Gln Glu Gly Ser
                 665                 670                 675

 Arg Ala Leu Thr Ser Glu Ala Arg Leu Cys Tyr Val Cys Ser Gly
                 680                 685                 690

 Ser Val Glu Arg Leu Val Glu Cys Trp Ala Lys Cys His Gln Ala
                 695                 700                 705

 Leu Ser Pro Met Ala Leu Gln Asp Leu Met Glu Lys Val Met Val
                 710                 715                 720

 Leu Asn Arg Ser Leu Glu Gln Leu Arg Gly Pro His Gly Val Ser
                 725                 730                 735

 Pro Gly Pro Ala Thr Thr Tyr Arg Val Thr Gln Tyr Ala Asn Leu
                 740                 745                 750

 Leu Ala Ala Gln Gly Ser Leu Ala Thr Ala Met Ser Phe Leu Pro
                 755                 760                 765

 Arg Asp Cys Ala Gln Pro Pro Val Gln Gln Leu Arg Asp Arg Leu
                 770                 775                 780

 Phe His Ala Gln Gly Ser Ala Val Leu Gly Gln Gln Ser Pro Pro
                 785                 790                 795

 Phe Pro Phe Pro Arg Ile Val Val Gly Ala Thr Leu His Ser Lys
                 800                 805                 810

 Glu Thr Ser Ser Tyr Arg Leu Gly Ser Gln Pro Ser His Gln Val
                 815                 820                 825

 Pro Thr Pro Ser Pro Arg Pro Arg Val Phe Thr Pro Gln Ser Ser
                 830                 835                 840

 Pro Ala Met Pro Leu Ala Pro Ser His Pro Ser Pro Tyr Gln Gly
                 845                 850                 855

 Pro Arg Thr Gln Asn Ile Ser Asp Tyr Arg Ala Pro Gly Pro Gln
                 860                 865                 870

 Ala Ile Gln Pro Leu Pro Leu Ser Pro Gly Val Arg Pro Ala Ser
                 875                 880                 885

 Ser Gln Pro Gln Leu Leu Gly Gly Gln Arg Val Gln Val Pro Asn
                 890                 895                 900

 Pro Val Gly Phe Pro Gly Thr Trp Pro Leu Pro Gly Ser Pro Leu
                 905                 910                 915

 Pro Met Ala Cys Pro Gly Ile Met Arg Pro Gly Ser Thr Ser Leu
                 920                 925                 930

 Pro Glu Thr Pro Arg Leu Phe Pro Leu Leu Pro Leu Arg Pro Leu
                 935                 940                 945

 Gly Pro Gly Arg Met Val Ser His Thr Pro Ala Pro Pro Ala Ser
                 950                 955                 960

 Phe Pro Val Pro Tyr Leu Pro Gly Asp Pro Gly Ala Pro Cys Ser
                 965                 970                 975

 Ser Val Leu Pro Thr Thr Gly Ile Leu Thr Pro His Pro Gly Pro
                 980                 985                 990

 Gln Asp Ser Trp Lys Glu Ala Pro Ala Pro Arg Gly Asn Leu Gln
                 995                1000                1005

 Arg Asn Lys Leu Pro Glu Thr Phe Met Pro Pro Ala Pro Ile Thr
                1010                1015                1020

 Ala Pro Val Met Ser Leu Thr Pro Glu Leu Gln Gly Ile Leu Pro
                1025                1030                1035

 Ser Gln Pro Pro Val Ser Ser Val Ser His Ala Pro Pro Gly Val
                1040                1045                1050

 Pro Gly Glu Leu Ser Leu Gln Leu Gln His Leu Pro Pro Glu Lys
                1055                1060                1065

 Met Glu Arg Lys Glu Leu Pro Pro Glu His Gln Ser Leu Lys Ser
                1070                1075                1080

 Ser Phe Glu Ala Leu Leu Gln Arg Cys Ser Leu Ser Ala Thr Asp
                1085                1090                1095

 Leu Lys Thr Lys Arg Lys Leu Glu Glu Ala Ala Gln Arg Leu Glu
                1100                1105                1110

 Tyr Leu Tyr Glu Lys Leu Cys Glu Gly Thr Leu Ser Pro His Val
                1115                1120                1125

 Val Ala Gly Leu His Glu Val Ala Arg Cys Val Asp Ala Gly Ser
                1130                1135                1140

 Phe Glu Gln Gly Leu Ala Val His Ala Gln Val Ala Gly Cys Ser
                1145                1150                1155

 Ser Phe Ser Glu Val Ser Ser Phe Met Pro Ile Leu Lys Ala Val
                1160                1165                1170

 Leu Ile Ile Ala His Lys Leu Leu Val
                1175

<210> 2137
<211> 1375
<212> DNA
<213> Homo sapien

<400> 2137
 gtttgaaatc ggaaagttgg cggggctgcg ggagctgagc ctagagtccg 50

 gctgttggct agagtgggcg cggatctggt gtggggaagg cggcgggact 100

 caggcctgcc tgcgaagcat tgtcctacat aatggtagag gacgaactgg 150

 cacttttcga taaaagcata aatgaatttt ggaataaatt caaaagtacg 200

 gacacctcct gtcagatggc gggactaaga gatacctaca aggattccat 250

 caaagcattt gcagaaaagc tgtctgtgaa attaaaggaa gaagaacgaa 300

 tggttgagat gtttctggaa tatcaaaatc agatcagcag gcaaaataag 350

 ctcattcaag aaaaaaagga taacttgtta aaattgattg ctgaagtaaa 400

 aggcaaaaag caggaattgg aagtactgac tgcaaatatc caggatctta 450

 aggaagaata ttctaggaag aaggaaacta tttctactgc taataaagcg 500

 aatgcagaga ggttgaaaag gctgcagaaa tctgcagact tgtataaaga 550

 tcgacttgga ctagaaattc gaaaaattta tggtgagaaa ttgcagttta 600

 ttttcactaa tattgaccct aagaatcctg agagcccatt tatgttttcc 650

 ttacatctca atgaagcaag ggactatgaa gtgtcagata gtgcccctca 700

 tcttgagggc ctagcagaat ttcaagagaa tgtaaggaag accaacaatt 750

 tttcagcttt tcttgccaat gttcggaaag cttttactgc cacggtttat 800

 aattaacata caaatagtgt atataaaaac ggtttatttt tcttctctat 850

 tacatatctc tttttttctt gtttttatta ttattatact ttaagtttta 900

 gggtacatgt gcacaatgtg caggtttgtt acatatgtat acatgtgcca 950

 tattggtgtg ctgcacccat taactcgtca tttcattagg tatatctcct 1000

 aatgctatcc ctcccccctc ccccaaccca caacagtccc cgttgtgtga 1050

 tgttcccctt cctgtgtcca tgtgttctca ttgttcaatt cccacctagg 1100

 agtgagaata tgtggtgttt ggttttttgt cctttcgata gtttgctgag 1150

 aatgatggtt tccagcttca tccatgttcc tacaaaggac atgaactcat 1200

 ccttttttat ggctgcatag tattccatgg tgtatatgtg ccacattttc 1250

 ttaatccagt ctatcattgt tggacatttg ggttggttcc aagtctttgc 1300

 tattgtgaat agtgccgaaa taaacatacg tgtgcatgtg tctttaaaaa 1350

 aaaaaaaaaa aaaaaaaaaa aaaaa 1375

<210> 2138
<211> 224
<212> PRT
<213> Homo sapien

<400> 2138
 Met Val Glu Asp Glu Leu Ala Leu Phe Asp Lys Ser Ile Asn Glu
   1               5                  10                  15

 Phe Trp Asn Lys Phe Lys Ser Thr Asp Thr Ser Cys Gln Met Ala
                  20                  25                  30

 Gly Leu Arg Asp Thr Tyr Lys Asp Ser Ile Lys Ala Phe Ala Glu
                  35                  40                  45

 Lys Leu Ser Val Lys Leu Lys Glu Glu Glu Arg Met Val Glu Met
                  50                  55                  60

 Phe Leu Glu Tyr Gln Asn Gln Ile Ser Arg Gln Asn Lys Leu Ile
                  65                  70                  75

 Gln Glu Lys Lys Asp Asn Leu Leu Lys Leu Ile Ala Glu Val Lys
                  80                  85                  90

 Gly Lys Lys Gln Glu Leu Glu Val Leu Thr Ala Asn Ile Gln Asp
                  95                 100                 105

 Leu Lys Glu Glu Tyr Ser Arg Lys Lys Glu Thr Ile Ser Thr Ala
                 110                 115                 120

 Asn Lys Ala Asn Ala Glu Arg Leu Lys Arg Leu Gln Lys Ser Ala
                 125                 130                 135

 Asp Leu Tyr Lys Asp Arg Leu Gly Leu Glu Ile Arg Lys Ile Tyr
                 140                 145                 150

 Gly Glu Lys Leu Gln Phe Ile Phe Thr Asn Ile Asp Pro Lys Asn
                 155                 160                 165

 Pro Glu Ser Pro Phe Met Phe Ser Leu His Leu Asn Glu Ala Arg
                 170                 175                 180

 Asp Tyr Glu Val Ser Asp Ser Ala Pro His Leu Glu Gly Leu Ala
                 185                 190                 195

 Glu Phe Gln Glu Asn Val Arg Lys Thr Asn Asn Phe Ser Ala Phe
                 200                 205                 210

 Leu Ala Asn Val Arg Lys Ala Phe Thr Ala Thr Val Tyr Asn
                 215                 220

<210> 2139
<211> 855
<212> DNA
<213> Homo sapien

<400> 2139
 gcctgcgcgg tagtgggacc cgaccctgtc tccagtgggc gtcttgggcc 50

 ccggctctat tctgggctgc gggcctggga agggctcgcc gggtgccaaa 100

 tgagctgtcc taactctgcg gggctgcagc ttcctgcatg atgctgggga 150

 gcttggcgcc tgacccagga tctagaaggc actctgggca ggccgcgctc 200

 cgcccacgaa ggtacccaac cctctgggat agatgcagga agcgatggtt 250

 aagacccatt ttcacccaac ttctcgccgc aggtctggct taccacacgc 300

 tcctccccat tcccagtgag ccgctttttg cagcaccagg cgaacactta 350

 caccagtgct ttgtaaagga atcttattgt ccaccccgtg tcttggcaaa 400

 agaacagtga tcacacagat tcctacttgg gctctttcct ttaatcttcg 450

 gaggctgagt ttgcccaact caggtttaac caccaaggac tctgagagct 500

 ggcaggtctg agtaaccctg gtaacaattc tcttcacctt atcaaaacct 550

 gagctaaaac caatgcatca gctgatgatg acagcagaga gtggcagggc 600

 tgaggaccca aagtcatttc ccaggctggc ggagaataaa ctgccaggga 650

 gaagaatgag aagacaggag acaaactgtt tggaaagcta aatcttccct 700

 cttaatgaat aaaggttttt gccttgtctt aaagtttctg agtcctaatt 750

 ttggcaaaat aaataactta tggtaatctg gaattgtatt ttgtaatatt 800

 aagtgttttg aacctctaac atttacttcc caaaatcaaa cttcagtttc 850

 aaaat 855

<210> 2140
<211> 90
<212> PRT
<213> Homo sapien

<400> 2140
 Met Met Leu Gly Ser Leu Ala Pro Asp Pro Gly Ser Arg Arg His
   1               5                  10                  15

 Ser Gly Gln Ala Ala Leu Arg Pro Arg Arg Tyr Pro Thr Leu Trp
                  20                  25                  30

 Asp Arg Cys Arg Lys Arg Trp Leu Arg Pro Ile Phe Thr Gln Leu
                  35                  40                  45

 Leu Ala Ala Gly Leu Ala Tyr His Thr Leu Leu Pro Ile Pro Ser
                  50                  55                  60

 Glu Pro Leu Phe Ala Ala Pro Gly Glu His Leu His Gln Cys Phe
                  65                  70                  75

 Val Lys Glu Ser Tyr Cys Pro Pro Arg Val Leu Ala Lys Glu Gln
                  80                  85                  90

<210> 2141
<211> 2000
<212> DNA
<213> Homo sapien

<400> 2141
 cctgtgaaca ctatagcgct gagagagaca gtctgaaagc agaggaagac 50

 atcgatcagt aacaccaaga gacaccaaag ttgaaagttt tgttttcttt 100

 ccctctgttt tatttttccc ccgtgtgtcc ctactatggt cagaaagcct 150

 gttgtgtcca ccatctccaa aggaggttac ctgcagggaa atgttaacgg 200

 gaggctgcct tccctgggca acaaggagcc acctgggcag gagaaagtgc 250

 agctgaagag gaaagtcact ttactgaggg gagtctccat tatcattggc 300

 accatcattg gagcaggaat cttcatctct cctaagggcg tgctccagaa 350

 cacgggcagc gtgggcatgt ctctgaccat ctggacggtg tgtggggtcc 400

 tgtcactatt tggagctttg tcttatgctg aattgggaac aactataaag 450

 aaatctggag gtcattacac atatattttg gaagtctttg gtccattacc 500

 agcttttgta cgagtctggg tggaactcct cataatacgc cctgcagcta 550

 ctgctgtgat atccctggca tttggacgct acattctgga accatttttt 600

 attcaatgtg aaatccctga acttgcgatc aagctcatta cagctgtggg 650

 cataactgta gtgatggtcc taaatagcat gagtgtcagc tggagcgccc 700

 ggatccagat tttcttaacc ttttgcaagc tcacagcaat tctgataatt 750

 atagtccctg gagttatgca gctaattaaa ggtcaaacgc agaactttaa 800

 agacgccttt tcaggaagag attcaagtat tacgcggttg ccactggctt 850

 tttattatgg aatgtatgca tatgctggct ggttttacct caactttgtt 900

 actgaagaag tagaaaaccc tgaaaaaacc attccccttg caatatgtat 950

 atccatggcc attgtcacca ttggctatgt gctgacaaat gtggcctact 1000

 ttacgaccat taatgctgag gagctgctgc tttcaaatgc agtggcagtg 1050

 accttttctg agcggctact gggaaatttc tcattagcag ttccgatctt 1100

 tgttgccctc tcctgctttg gctccatgaa cggtggtgtg tttgctgtct 1150

 ccaggttatt ctatgttgcg tctcgagagg gtcaccttcc agaaatcctc 1200

 tccatgattc atgtccgcaa gcacactcct ctaccagctg ttattgtttt 1250

 gcaccctttg acaatgataa tgctcttctc tggagacctc gacagtcttt 1300

 tgaatttcct cagttttgcc aggtggcttt ttattgggct ggcagttgct 1350

 gggctgattt atcttcgata caaatgccca gatatgcatc gtcctttcaa 1400

 ggtgccactg ttcatcccag ctttgttttc cttcacatgc ctcttcatgg 1450

 ttgccctttc cctctattcg gacccattta gtacagggat tggcttcgtc 1500

 atcactctga ctggagtccc tgcgtattat ctctttatta tatgggacaa 1550

 gaaacccagg tggtttagaa taatgtcagg gttcctagca ctgatgcctg 1600

 cacaagcatg tgatatgtga aataaaatgg attcttctat agctaaatga 1650

 gttccctctg gggagagttc tggtactgca atcacaatgc cagatggtgt 1700

 ttatgggcta tttgtgtaag taagtggtaa gatgctatga agtaagtgtg 1750

 tttgttttca tcttatggaa actcttgatg catgtgcttt tgtatggaat 1800

 aaattttggt gcaatatgat gtcattcaac tttgcattga attgaatttt 1850

 ggttgtattt atatgtatta tacctgtcac gcttctagtt gcttcaacca 1900

 ttttataacc atttttgtac atattttact tgaaaatatt ttaaatggaa 1950

 atttaaataa acatttgata gtttacataa taaaaaaaaa aaaaaaaaaa 2000

<210> 2142
<211> 494
<212> PRT
<213> Homo sapien

<400> 2142
 Met Val Arg Lys Pro Val Val Ser Thr Ile Ser Lys Gly Gly Tyr
   1               5                  10                  15

 Leu Gln Gly Asn Val Asn Gly Arg Leu Pro Ser Leu Gly Asn Lys
                  20                  25                  30

 Glu Pro Pro Gly Gln Glu Lys Val Gln Leu Lys Arg Lys Val Thr
                  35                  40                  45

 Leu Leu Arg Gly Val Ser Ile Ile Ile Gly Thr Ile Ile Gly Ala
                  50                  55                  60

 Gly Ile Phe Ile Ser Pro Lys Gly Val Leu Gln Asn Thr Gly Ser
                  65                  70                  75

 Val Gly Met Ser Leu Thr Ile Trp Thr Val Cys Gly Val Leu Ser
                  80                  85                  90

 Leu Phe Gly Ala Leu Ser Tyr Ala Glu Leu Gly Thr Thr Ile Lys
                  95                 100                 105

 Lys Ser Gly Gly His Tyr Thr Tyr Ile Leu Glu Val Phe Gly Pro
                 110                 115                 120

 Leu Pro Ala Phe Val Arg Val Trp Val Glu Leu Leu Ile Ile Arg
                 125                 130                 135

 Pro Ala Ala Thr Ala Val Ile Ser Leu Ala Phe Gly Arg Tyr Ile
                 140                 145                 150

 Leu Glu Pro Phe Phe Ile Gln Cys Glu Ile Pro Glu Leu Ala Ile
                 155                 160                 165

 Lys Leu Ile Thr Ala Val Gly Ile Thr Val Val Met Val Leu Asn
                 170                 175                 180

 Ser Met Ser Val Ser Trp Ser Ala Arg Ile Gln Ile Phe Leu Thr
                 185                 190                 195

 Phe Cys Lys Leu Thr Ala Ile Leu Ile Ile Ile Val Pro Gly Val
                 200                 205                 210

 Met Gln Leu Ile Lys Gly Gln Thr Gln Asn Phe Lys Asp Ala Phe
                 215                 220                 225

 Ser Gly Arg Asp Ser Ser Ile Thr Arg Leu Pro Leu Ala Phe Tyr
                 230                 235                 240

 Tyr Gly Met Tyr Ala Tyr Ala Gly Trp Phe Tyr Leu Asn Phe Val
                 245                 250                 255

 Thr Glu Glu Val Glu Asn Pro Glu Lys Thr Ile Pro Leu Ala Ile
                 260                 265                 270

 Cys Ile Ser Met Ala Ile Val Thr Ile Gly Tyr Val Leu Thr Asn
                 275                 280                 285

 Val Ala Tyr Phe Thr Thr Ile Asn Ala Glu Glu Leu Leu Leu Ser
                 290                 295                 300

 Asn Ala Val Ala Val Thr Phe Ser Glu Arg Leu Leu Gly Asn Phe
                 305                 310                 315

 Ser Leu Ala Val Pro Ile Phe Val Ala Leu Ser Cys Phe Gly Ser
                 320                 325                 330

 Met Asn Gly Gly Val Phe Ala Val Ser Arg Leu Phe Tyr Val Ala
                 335                 340                 345

 Ser Arg Glu Gly His Leu Pro Glu Ile Leu Ser Met Ile His Val
                 350                 355                 360

 Arg Lys His Thr Pro Leu Pro Ala Val Ile Val Leu His Pro Leu
                 365                 370                 375

 Thr Met Ile Met Leu Phe Ser Gly Asp Leu Asp Ser Leu Leu Asn
                 380                 385                 390

 Phe Leu Ser Phe Ala Arg Trp Leu Phe Ile Gly Leu Ala Val Ala
                 395                 400                 405

 Gly Leu Ile Tyr Leu Arg Tyr Lys Cys Pro Asp Met His Arg Pro
                 410                 415                 420

 Phe Lys Val Pro Leu Phe Ile Pro Ala Leu Phe Ser Phe Thr Cys
                 425                 430                 435

 Leu Phe Met Val Ala Leu Ser Leu Tyr Ser Asp Pro Phe Ser Thr
                 440                 445                 450

 Gly Ile Gly Phe Val Ile Thr Leu Thr Gly Val Pro Ala Tyr Tyr
                 455                 460                 465

 Leu Phe Ile Ile Trp Asp Lys Lys Pro Arg Trp Phe Arg Ile Met
                 470                 475                 480

 Ser Gly Phe Leu Ala Leu Met Pro Ala Gln Ala Cys Asp Met
                 485                 490

<210> 2143
<211> 2648
<212> DNA
<213> Homo sapien

<400> 2143
 gcctctctcc atcagacacc ccaaggttcc atccgaagca ggcggagcac 50

 cgaacgcacc ccggggtggt cagggacccc catccgtgct gccccctagg 100

 agcccgcgcc tctcctctgc gccccgcctc tcgggccgca acatcgcgcg 150

 gttcctttaa cagcgcgctg gcagggtgtg ggaagcagga ccgcgtcctc 200

 ccgccccctc ccatccgagt ttcaggtgaa ttggtcaccg agggaggagg 250

 ccgacacacc acacctacac tcccgcgtcc acctctccct ccctgcttcc 300

 tctggcggag gcggcaggaa ccgagagcca ggtccagagc gccgaggagc 350

 cggtctagga cgcagcagat tggtttatct tggaagctaa agggcattgc 400

 tcatcctgaa gatcagctga ccattgacaa tcagccatgt catccaggcc 450

 tcttgaaagt ccacctcctt acaggcctga tgaattcaaa ccgaatcatt 500

 atgcaccaag caatgacata tatggtggag agatgcatgt tcgaccaatg 550

 ctctctcagc cagcctactc tttttaccca gaagatgaaa ttcttcactt 600

 ctacaaatgg acctctcctc caggagtgat tcggatcctg tctatgctca 650

 ttattgtgat gtgcattgcc atctttgcct gtgtggcctc cacgcttgcc 700

 tgggacagag gctatggaac ttccctttta ggaggtagtg taggctaccc 750

 ttatggagga agtggctttg gtagctacgg aagtggctat ggctatggct 800

 atggttatgg ctatggctac ggaggctata cagacccaag agcagcaaag 850

 ggcttcatgt tggccatggc tgccttttgt ttcattgccg cgttggtgat 900

 ctttgttacc agtgttataa gatctgaaat gtccagaaca agaagatact 950

 acttaagtgt gataatagtg agtgctatcc tgggcatcat ggtgtttatt 1000

 gccacaattg tctatataat gggagtgaac ccaactgctc agtcttctgg 1050

 atctctatat ggttcacaaa tatatgccct ctgcaaccaa ttttatacac 1100

 ctgcagctac tggactctac gtggatcagt atttgtatca ctactgtgtt 1150

 gtggatcccc aggaggccat tgccattgta ctggggttca tgattattgt 1200

 ggcttttgct ttaataattt tctttgctgt gaaaactcga agaaagatgg 1250

 acaggtatga caagtccaat attttgtggg acaaggaaca catttatgat 1300

 gagcagcccc ccaatgtcga ggagtgggtt aaaaatgtgt ctgcaggcac 1350

 acaggacgtg ccttcacccc catctgacta tgtggaaaga gttgacagtc 1400

 ccatggcata ctcttccaat ggcaaagtga atgacaagcg gttttatcca 1450

 gagtcttcct ataaatccac gccggttcct gaagtggttc aggagcttcc 1500

 attaacttcg cctgtggatg acttcaggca gcctcgttac agcagcggtg 1550

 gtaactttga gacaccttca aaaagagcac ctgcaaaggg aagagcagga 1600

 aggtcaaaga gaacagagca agatcactat gagacagact acacaactgg 1650

 cggcgagtcc tgtgatgagc tggaggagga ctggatcagg gaatatccac 1700

 ctatcacttc agatcaacaa agacaactgt acaagaggaa ttttgacact 1750

 ggcctacagg aatacaagag cttacaatca gaacttgatg agatcaataa 1800

 agaactctcc cgtttggata aagaattgga tgactataga gaagaaagtg 1850

 aagagtacat ggctgctgct gatgaataca atagactgaa gcaagtgaag 1900

 ggatctgcag attacaaaag taagaagaat cattgcaagc agttaaagag 1950

 caaattgtca cacatcaaga agatggttgg agactatgat agacagaaaa 2000

 catagaaggc tgatgccaag ttgtttgaga aattaagtat ctgacatctc 2050

 tgcaatcttc tcagaaggca aatgactttg gaccataacc ccggaagcca 2100

 aacctctgtg agcatcacaa agttttggtt gctttaacat catcagtatt 2150

 gaagcatttt ataaatcgct tttgataatc aactgggctg aacactccaa 2200

 ttaaggattt tatgctttaa acattggttc ttgtattaag aatgaaatac 2250

 tgtttgaggt ttttaagcct taaaggaagg ttctggtgtg aactaaactt 2300

 tcacacccca gacgatgtct tcatacctac atgtatttgt ttgcataggt 2350

 gatctcattt aatcctctca accacctttc agataactgt tatttataat 2400

 cacttttttc cacataagga aactgggttc ctgcaatgaa gtctctgaag 2450

 tgaaactgct tgtttcctag cacacacttt tggttaagtc tgttttatga 2500

 cttcattaat aataaattcc ctggcctttc atattttagc tactatatat 2550

 gtgatgatct accagcctcc ctattttttt tctgttatat aaatggttaa 2600

 aagaggtttt tcttaaataa taaagatcat gtaaaagtaa aaaaaaaa 2648

<210> 2144
<211> 522
<212> PRT
<213> Homo sapien

<400> 2144
 Met Ser Ser Arg Pro Leu Glu Ser Pro Pro Pro Tyr Arg Pro Asp
   1               5                  10                  15

 Glu Phe Lys Pro Asn His Tyr Ala Pro Ser Asn Asp Ile Tyr Gly
                  20                  25                  30

 Gly Glu Met His Val Arg Pro Met Leu Ser Gln Pro Ala Tyr Ser
                  35                  40                  45

 Phe Tyr Pro Glu Asp Glu Ile Leu His Phe Tyr Lys Trp Thr Ser
                  50                  55                  60

 Pro Pro Gly Val Ile Arg Ile Leu Ser Met Leu Ile Ile Val Met
                  65                  70                  75

 Cys Ile Ala Ile Phe Ala Cys Val Ala Ser Thr Leu Ala Trp Asp
                  80                  85                  90

 Arg Gly Tyr Gly Thr Ser Leu Leu Gly Gly Ser Val Gly Tyr Pro
                  95                 100                 105

 Tyr Gly Gly Ser Gly Phe Gly Ser Tyr Gly Ser Gly Tyr Gly Tyr
                 110                 115                 120

 Gly Tyr Gly Tyr Gly Tyr Gly Tyr Gly Gly Tyr Thr Asp Pro Arg
                 125                 130                 135

 Ala Ala Lys Gly Phe Met Leu Ala Met Ala Ala Phe Cys Phe Ile
                 140                 145                 150

 Ala Ala Leu Val Ile Phe Val Thr Ser Val Ile Arg Ser Glu Met
                 155                 160                 165

 Ser Arg Thr Arg Arg Tyr Tyr Leu Ser Val Ile Ile Val Ser Ala
                 170                 175                 180

 Ile Leu Gly Ile Met Val Phe Ile Ala Thr Ile Val Tyr Ile Met
                 185                 190                 195

 Gly Val Asn Pro Thr Ala Gln Ser Ser Gly Ser Leu Tyr Gly Ser
                 200                 205                 210

 Gln Ile Tyr Ala Leu Cys Asn Gln Phe Tyr Thr Pro Ala Ala Thr
                 215                 220                 225

 Gly Leu Tyr Val Asp Gln Tyr Leu Tyr His Tyr Cys Val Val Asp
                 230                 235                 240

 Pro Gln Glu Ala Ile Ala Ile Val Leu Gly Phe Met Ile Ile Val
                 245                 250                 255

 Ala Phe Ala Leu Ile Ile Phe Phe Ala Val Lys Thr Arg Arg Lys
                 260                 265                 270

 Met Asp Arg Tyr Asp Lys Ser Asn Ile Leu Trp Asp Lys Glu His
                 275                 280                 285

 Ile Tyr Asp Glu Gln Pro Pro Asn Val Glu Glu Trp Val Lys Asn
                 290                 295                 300

 Val Ser Ala Gly Thr Gln Asp Val Pro Ser Pro Pro Ser Asp Tyr
                 305                 310                 315

 Val Glu Arg Val Asp Ser Pro Met Ala Tyr Ser Ser Asn Gly Lys
                 320                 325                 330

 Val Asn Asp Lys Arg Phe Tyr Pro Glu Ser Ser Tyr Lys Ser Thr
                 335                 340                 345

 Pro Val Pro Glu Val Val Gln Glu Leu Pro Leu Thr Ser Pro Val
                 350                 355                 360

 Asp Asp Phe Arg Gln Pro Arg Tyr Ser Ser Gly Gly Asn Phe Glu
                 365                 370                 375

 Thr Pro Ser Lys Arg Ala Pro Ala Lys Gly Arg Ala Gly Arg Ser
                 380                 385                 390

 Lys Arg Thr Glu Gln Asp His Tyr Glu Thr Asp Tyr Thr Thr Gly
                 395                 400                 405

 Gly Glu Ser Cys Asp Glu Leu Glu Glu Asp Trp Ile Arg Glu Tyr
                 410                 415                 420

 Pro Pro Ile Thr Ser Asp Gln Gln Arg Gln Leu Tyr Lys Arg Asn
                 425                 430                 435

 Phe Asp Thr Gly Leu Gln Glu Tyr Lys Ser Leu Gln Ser Glu Leu
                 440                 445                 450

 Asp Glu Ile Asn Lys Glu Leu Ser Arg Leu Asp Lys Glu Leu Asp
                 455                 460                 465

 Asp Tyr Arg Glu Glu Ser Glu Glu Tyr Met Ala Ala Ala Asp Glu
                 470                 475                 480

 Tyr Asn Arg Leu Lys Gln Val Lys Gly Ser Ala Asp Tyr Lys Ser
                 485                 490                 495

 Lys Lys Asn His Cys Lys Gln Leu Lys Ser Lys Leu Ser His Ile
                 500                 505                 510

 Lys Lys Met Val Gly Asp Tyr Asp Arg Gln Lys Thr
                 515                 520

<210> 2145
<211> 1637
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1315, 1498-1499
<223> Unknown base

<400> 2145
 cgggggaggc gtgactttcc cctcgggtcc aggtagggcc tggagctgct 50

 gcaagtgccg cctgtgctgg ggaagggacc atgtggctgc cttgggctct 100

 gttgcttctc tgggtcccag gatgttttgc tctgagcaaa tgcaggaccg 150

 tggcgggccc gtggggatcc ctgagtgtgc agtgtcccta tgagaaggaa 200

 cacaggaccc tcaacaaata ctggtgcaga ccaccacaga ttttcctatg 250

 tgacaagatt gtggagacca aagggtcagc aggaaaaagg aacggccgag 300

 tgtccatcag ggacagtcct gcaaacctca gcttcacagt gaccctggag 350

 aatctcacag aggaggatgc aggcacctac tggtgtgggg tggatacacc 400

 atggctccga gactttcatg atcccgttgt cgaggttgag gtgtccgtgt 450

 tcccggcatc aacgtcaatg acacctgcaa gtatcactgc ggccaagacc 500

 tcaacaatca caactgcatt tccacctgta tcatccacta ccctgtttgc 550

 agtgggtgcc acccacagtg ccagcatcca ggaggaaact gaggaggtgg 600

 tgaactcaca gctcccgctg ctcctctccc tgctggcatt gttgctgctt 650

 ctgttggtgg gggcctccct gctagcctgg aggatgtttc agaaatggat 700

 caaatggatc aaagctggtg accattcaga gctgtcccag aaccccaagc 750

 aggctgccac gcagagtgag ctgcactacg caaatctgga gctgctgatg 800

 tggcctctgc aggaaaagcc agcaccacca agggaggtgg aggtggaata 850

 cagcactgtg gcctccccca gggaagaact tcactatgcc tcggtggtgt 900

 ttgattctaa caccaacagg atagctgctc agaggcctcg ggaggaggaa 950

 ccagattcag attacagtgt gataaggaag acataggtcc tgcctcgcca 1000

 tcggagctct catgggcccc aggaagtcag ggacagctcc cttatacctg 1050

 gcccacgtcc ttctcagcct gccctcgaca acagtgacca acagacaggc 1100

 agctgggttt ccaggccatc cctctgttgc catcagcttg attggcttcc 1150

 ccgagggcca gcagggctgg ggctccggag agcagcagga agcactccca 1200

 gccaccagtg cctgtcacct ctttcccctt tgcccctgct tcatcccagc 1250

 tctgtgtgtg gaggacaaag cttcttcctg cgtggctcca ggaaaagatg 1300

 tggctcacgt aggtngcacc tgccaatagc tttgtcaatc acagccccat 1350

 aggaacgtct ggaattgctt gggagttggg gagaactgtc aagaagagtg 1400

 aagagagtgc caaagcggag atctgttcac ctgggtggag gggaccacta 1450

 agatcaagat caaagattct ccccatctca cagacaagga aactgagnna 1500

 gagggaggag agaattgctc atggctccag aactggtggc aagtttctct 1550

 ggactcttag gtttattttt aatatgaaat ataaaaacag tttcaaatat 1600

 cttattgagg gagaagtaaa aacttattta aaccccg 1637

<210> 2146
<211> 301
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1315, 1498-1499
<223> Unknown amino acid

<400> 2146
 Met Trp Leu Pro Trp Ala Leu Leu Leu Leu Trp Val Pro Gly Cys
   1               5                  10                  15

 Phe Ala Leu Ser Lys Cys Arg Thr Val Ala Gly Pro Trp Gly Ser
                  20                  25                  30

 Leu Ser Val Gln Cys Pro Tyr Glu Lys Glu His Arg Thr Leu Asn
                  35                  40                  45

 Lys Tyr Trp Cys Arg Pro Pro Gln Ile Phe Leu Cys Asp Lys Ile
                  50                  55                  60

 Val Glu Thr Lys Gly Ser Ala Gly Lys Arg Asn Gly Arg Val Ser
                  65                  70                  75

 Ile Arg Asp Ser Pro Ala Asn Leu Ser Phe Thr Val Thr Leu Glu
                  80                  85                  90

 Asn Leu Thr Glu Glu Asp Ala Gly Thr Tyr Trp Cys Gly Val Asp
                  95                 100                 105

 Thr Pro Trp Leu Arg Asp Phe His Asp Pro Val Val Glu Val Glu
                 110                 115                 120

 Val Ser Val Phe Pro Ala Ser Thr Ser Met Thr Pro Ala Ser Ile
                 125                 130                 135

 Thr Ala Ala Lys Thr Ser Thr Ile Thr Thr Ala Phe Pro Pro Val
                 140                 145                 150

 Ser Ser Thr Thr Leu Phe Ala Val Gly Ala Thr His Ser Ala Ser
                 155                 160                 165

 Ile Gln Glu Glu Thr Glu Glu Val Val Asn Ser Gln Leu Pro Leu
                 170                 175                 180

 Leu Leu Ser Leu Leu Ala Leu Leu Leu Leu Leu Leu Val Gly Ala
                 185                 190                 195

 Ser Leu Leu Ala Trp Arg Met Phe Gln Lys Trp Ile Lys Trp Ile
                 200                 205                 210

 Lys Ala Gly Asp His Ser Glu Leu Ser Gln Asn Pro Lys Gln Ala
                 215                 220                 225

 Ala Thr Gln Ser Glu Leu His Tyr Ala Asn Leu Glu Leu Leu Met
                 230                 235                 240

 Trp Pro Leu Gln Glu Lys Pro Ala Pro Pro Arg Glu Val Glu Val
                 245                 250                 255

 Glu Tyr Ser Thr Val Ala Ser Pro Arg Glu Glu Leu His Tyr Ala
                 260                 265                 270

 Ser Val Val Phe Asp Ser Asn Thr Asn Arg Ile Ala Ala Gln Arg
                 275                 280                 285

 Pro Arg Glu Glu Glu Pro Asp Ser Asp Tyr Ser Val Ile Arg Lys
                 290                 295                 300

 Thr


<210> 2147
<211> 834
<212> DNA
<213> Homo sapien

<400> 2147
 atgtctgctg aagtcatcca tcaggttgaa gaagcacttg atacagatga 50

 gaaggagatg ctgctctttt tgtgccggga tgttgctata gatgtggttc 100

 cacctaatgt cagggacctt ctggatattt tacgggaaag aggtaagctg 150

 tctgtcgggg acttggctga actgctctac agagtgaggc gatttgacct 200

 gctcaaacgt atcttgaaga tggacagaaa agctgtggag acccacctgc 250

 tcaggaaccc tcaccttgtt tcggactata gagtgctgat ggcagagatt 300

 ggtgaggatt tggataaatc tgatgtgtcc tcattaattt tcctcatgaa 350

 ggattacatg ggccgaggca agataagcaa ggagaagatt tcttgggacc 400

 ttgtggttga gttggagaaa ctaaatctgg ttgccccaga tcaactggat 450

 ttattagaaa aatgcctaaa gaacatccac agaatagacc tgaagacaaa 500

 aatccagaag tacaagcagt ctgttcaagg agcagggaca agttacagga 550

 atgttctcca agcagcaatc caaaagagtc tcaaggatcc ttcaaataac 600

 ttcaggatga taacacccta tgcccattgt cctgatctga aaattcttgg 650

 aaattgttcc atgtgattaa catggaactg cctctactta atcattctga 700

 atgattaaat cgtttcattt tctaaatgtg ttataatgtg tttagccctt 750

 tcttgttgct gtatgtttag atgctttcca atcttttgtt actactaata 800

 atgctataaa ataaatatcc ttgtacttct ttga 834

<210> 2148
<211> 221
<212> PRT
<213> Homo sapien

<400> 2148
 Met Ser Ala Glu Val Ile His Gln Val Glu Glu Ala Leu Asp Thr
   1               5                  10                  15

 Asp Glu Lys Glu Met Leu Leu Phe Leu Cys Arg Asp Val Ala Ile
                  20                  25                  30

 Asp Val Val Pro Pro Asn Val Arg Asp Leu Leu Asp Ile Leu Arg
                  35                  40                  45

 Glu Arg Gly Lys Leu Ser Val Gly Asp Leu Ala Glu Leu Leu Tyr
                  50                  55                  60

 Arg Val Arg Arg Phe Asp Leu Leu Lys Arg Ile Leu Lys Met Asp
                  65                  70                  75

 Arg Lys Ala Val Glu Thr His Leu Leu Arg Asn Pro His Leu Val
                  80                  85                  90

 Ser Asp Tyr Arg Val Leu Met Ala Glu Ile Gly Glu Asp Leu Asp
                  95                 100                 105

 Lys Ser Asp Val Ser Ser Leu Ile Phe Leu Met Lys Asp Tyr Met
                 110                 115                 120

 Gly Arg Gly Lys Ile Ser Lys Glu Lys Ile Ser Trp Asp Leu Val
                 125                 130                 135

 Val Glu Leu Glu Lys Leu Asn Leu Val Ala Pro Asp Gln Leu Asp
                 140                 145                 150

 Leu Leu Glu Lys Cys Leu Lys Asn Ile His Arg Ile Asp Leu Lys
                 155                 160                 165

 Thr Lys Ile Gln Lys Tyr Lys Gln Ser Val Gln Gly Ala Gly Thr
                 170                 175                 180

 Ser Tyr Arg Asn Val Leu Gln Ala Ala Ile Gln Lys Ser Leu Lys
                 185                 190                 195

 Asp Pro Ser Asn Asn Phe Arg Met Ile Thr Pro Tyr Ala His Cys
                 200                 205                 210

 Pro Asp Leu Lys Ile Leu Gly Asn Cys Ser Met
                 215                 220

<210> 2149
<211> 2762
<212> DNA
<213> Homo sapien

<400> 2149
 agcggggcgg ggcgccagcg ctgccttttc tcctgccggg tagtttcgct 50

 ttcctgcgca gagtctgcgg aggggctcgg ctgcaccggg gggatcgcgc 100

 ctggcagacc ccagaccgag cagaggcgac ccagcgcgct cgggagaggc 150

 tgcaccgccg cgcccccgcc tagcccttcc ggatcctgcg cgcagaaaag 200

 tttcatttgc tgtatgccat cctcgagagc tgtctaggtt aacgttcgca 250

 ctctgtgtat ataacctcga cagtcttggc acctaacgtg ctgtgcgtag 300

 ctgctccttt ggttgaatcc ccaggccctt gttggggcac aaggtggcag 350

 gatgtctcag tggtacgaac ttcagcagct tgactcaaaa ttcctggagc 400

 aggttcacca gctttatgat gacagttttc ccatggaaat cagacagtac 450

 ctggcacagt ggttagaaaa gcaagactgg gagcacgctg ccaatgatgt 500

 ttcatttgcc accatccgtt ttcatgacct cctgtcacag ctggatgatc 550

 aatatagtcg cttttctttg gagaataact tcttgctaca gcataacata 600

 aggaaaagca agcgtaatct tcaggataat tttcaggaag acccaatcca 650

 gatgtctatg atcatttaca gctgtctgaa ggaagaaagg aaaattctgg 700

 aaaacgccca gagatttaat caggctcagt cggggaatat tcagagcaca 750

 gtgatgttag acaaacagaa agagcttgac agtaaagtca gaaatgtgaa 800

 ggacaaggtt atgtgtatag agcatgaaat caagagcctg gaagatttac 850

 aagatgaata tgacttcaaa tgcaaaacct tgcagaacag agaacacgag 900

 accaatggtg tggcaaagag tgatcagaaa caagaacagc tgttactcaa 950

 gaagatgtat ttaatgcttg acaataagag aaaggaagta gttcacaaaa 1000

 taatagagtt gctgaatgtc actgaactta cccagaatgc cctgattaat 1050

 gatgaactag tggagtggaa gcggagacag cagagcgcct gtattggggg 1100

 gccgcccaat gcttgcttgg atcagctgca gaactggttc actatagttg 1150

 cggagagtct gcagcaagtt cggcagcagc ttaaaaagtt ggaggaattg 1200

 gaacagaaat acacctacga acatgaccct atcacaaaaa acaaacaagt 1250

 gttatgggac cgcaccttca gtcttttcca gcagctcatt cagagctcgt 1300

 ttgtggtgga aagacagccc tgcatgccaa cgcaccctca gaggccgctg 1350

 gtcttgaaga caggggtcca gttcactgtg aagttgagac tgttggtgaa 1400

 attgcaagag ctgaattata atttgaaagt caaagtctta tttgataaag 1450

 atgtgaatga gagaaataca gtaaaaggat ttaggaagtt caacattttg 1500

 ggcacgcaca caaaagtgat gaacatggag gagtccacca atggcagtct 1550

 ggcggctgaa tttcggcacc tgcaattgaa agaacagaaa aatgctggca 1600

 ccagaacgaa tgagggtcct ctcatcgtta ctgaagagct tcactccctt 1650

 agttttgaaa cccaattgtg ccagcctggt ttggtaattg acctcgagac 1700

 gacctctctg cccgttgtgg tgatctccaa cgtcagccag ctcccgagcg 1750

 gttgggcctc catcctttgg tacaacatgc tggtggcgga acccaggaat 1800

 ctgtccttct tcctgactcc accatgtgca cgatgggctc agctttcaga 1850

 agtgctgagt tggcagtttt cttctgtcac caaaagaggt ctcaatgtgg 1900

 accagctgaa catgttggga gagaagcttc ttggtcctaa cgccagcccc 1950

 gatggtctca ttccgtggac gaggttttgt aaggaaaata taaatgataa 2000

 aaattttccc ttctggcttt ggattgaaag catcctagaa ctcattaaaa 2050

 aacacctgct ccctctctgg aatgatgggt gcatcatggg cttcatcagc 2100

 aaggagcgag agcgtgccct gttgaaggac cagcagccgg ggaccttcct 2150

 gctgcggttc agtgagagct cccgggaagg ggccatcaca ttcacatggg 2200

 tggagcggtc ccagaacgga ggcgaacctg acttccatgc ggttgaaccc 2250

 tacacgaaga aagaactttc tgctgttact ttccctgaca tcattcgcaa 2300

 ttacaaagtc atggctgctg agaatattcc tgagaatccc ctgaagtatc 2350

 tgtatccaaa tattgacaaa gaccatgcct ttggaaagta ttactccagg 2400

 ccaaaggaag caccagagcc aatggaactt gatggcccta aaggaactgg 2450

 atatatcaag actgagttga tttctgtgtc tgaagtgtaa gtgaacacag 2500

 aagagtgaca tgtttacaaa cctcaagcca gccttgctcc tggctggggc 2550

 ctgttgaaga tgcttgtatt ttacttttcc attgtaattg ctatcgccat 2600

 cacagctgaa cttgttgaga tccccgtgtt actgcctatc agcattttac 2650

 tactttaaaa aaaaaaaaaa aagccaaaaa ccaaatttgt atttaaggta 2700

 tataaatttt cccaaaactg ataccctttg aaaaagtata aataaaatga 2750

 gcaaaagttg aa 2762

<210> 2150
<211> 712
<212> PRT
<213> Homo sapien

<400> 2150
 Met Ser Gln Trp Tyr Glu Leu Gln Gln Leu Asp Ser Lys Phe Leu
   1               5                  10                  15

 Glu Gln Val His Gln Leu Tyr Asp Asp Ser Phe Pro Met Glu Ile
                  20                  25                  30

 Arg Gln Tyr Leu Ala Gln Trp Leu Glu Lys Gln Asp Trp Glu His
                  35                  40                  45

 Ala Ala Asn Asp Val Ser Phe Ala Thr Ile Arg Phe His Asp Leu
                  50                  55                  60

 Leu Ser Gln Leu Asp Asp Gln Tyr Ser Arg Phe Ser Leu Glu Asn
                  65                  70                  75

 Asn Phe Leu Leu Gln His Asn Ile Arg Lys Ser Lys Arg Asn Leu
                  80                  85                  90

 Gln Asp Asn Phe Gln Glu Asp Pro Ile Gln Met Ser Met Ile Ile
                  95                 100                 105

 Tyr Ser Cys Leu Lys Glu Glu Arg Lys Ile Leu Glu Asn Ala Gln
                 110                 115                 120

 Arg Phe Asn Gln Ala Gln Ser Gly Asn Ile Gln Ser Thr Val Met
                 125                 130                 135

 Leu Asp Lys Gln Lys Glu Leu Asp Ser Lys Val Arg Asn Val Lys
                 140                 145                 150

 Asp Lys Val Met Cys Ile Glu His Glu Ile Lys Ser Leu Glu Asp
                 155                 160                 165

 Leu Gln Asp Glu Tyr Asp Phe Lys Cys Lys Thr Leu Gln Asn Arg
                 170                 175                 180

 Glu His Glu Thr Asn Gly Val Ala Lys Ser Asp Gln Lys Gln Glu
                 185                 190                 195

 Gln Leu Leu Leu Lys Lys Met Tyr Leu Met Leu Asp Asn Lys Arg
                 200                 205                 210

 Lys Glu Val Val His Lys Ile Ile Glu Leu Leu Asn Val Thr Glu
                 215                 220                 225

 Leu Thr Gln Asn Ala Leu Ile Asn Asp Glu Leu Val Glu Trp Lys
                 230                 235                 240

 Arg Arg Gln Gln Ser Ala Cys Ile Gly Gly Pro Pro Asn Ala Cys
                 245                 250                 255

 Leu Asp Gln Leu Gln Asn Trp Phe Thr Ile Val Ala Glu Ser Leu
                 260                 265                 270

 Gln Gln Val Arg Gln Gln Leu Lys Lys Leu Glu Glu Leu Glu Gln
                 275                 280                 285

 Lys Tyr Thr Tyr Glu His Asp Pro Ile Thr Lys Asn Lys Gln Val
                 290                 295                 300

 Leu Trp Asp Arg Thr Phe Ser Leu Phe Gln Gln Leu Ile Gln Ser
                 305                 310                 315

 Ser Phe Val Val Glu Arg Gln Pro Cys Met Pro Thr His Pro Gln
                 320                 325                 330

 Arg Pro Leu Val Leu Lys Thr Gly Val Gln Phe Thr Val Lys Leu
                 335                 340                 345

 Arg Leu Leu Val Lys Leu Gln Glu Leu Asn Tyr Asn Leu Lys Val
                 350                 355                 360

 Lys Val Leu Phe Asp Lys Asp Val Asn Glu Arg Asn Thr Val Lys
                 365                 370                 375

 Gly Phe Arg Lys Phe Asn Ile Leu Gly Thr His Thr Lys Val Met
                 380                 385                 390

 Asn Met Glu Glu Ser Thr Asn Gly Ser Leu Ala Ala Glu Phe Arg
                 395                 400                 405

 His Leu Gln Leu Lys Glu Gln Lys Asn Ala Gly Thr Arg Thr Asn
                 410                 415                 420

 Glu Gly Pro Leu Ile Val Thr Glu Glu Leu His Ser Leu Ser Phe
                 425                 430                 435

 Glu Thr Gln Leu Cys Gln Pro Gly Leu Val Ile Asp Leu Glu Thr
                 440                 445                 450

 Thr Ser Leu Pro Val Val Val Ile Ser Asn Val Ser Gln Leu Pro
                 455                 460                 465

 Ser Gly Trp Ala Ser Ile Leu Trp Tyr Asn Met Leu Val Ala Glu
                 470                 475                 480

 Pro Arg Asn Leu Ser Phe Phe Leu Thr Pro Pro Cys Ala Arg Trp
                 485                 490                 495

 Ala Gln Leu Ser Glu Val Leu Ser Trp Gln Phe Ser Ser Val Thr
                 500                 505                 510

 Lys Arg Gly Leu Asn Val Asp Gln Leu Asn Met Leu Gly Glu Lys
                 515                 520                 525

 Leu Leu Gly Pro Asn Ala Ser Pro Asp Gly Leu Ile Pro Trp Thr
                 530                 535                 540

 Arg Phe Cys Lys Glu Asn Ile Asn Asp Lys Asn Phe Pro Phe Trp
                 545                 550                 555

 Leu Trp Ile Glu Ser Ile Leu Glu Leu Ile Lys Lys His Leu Leu
                 560                 565                 570

 Pro Leu Trp Asn Asp Gly Cys Ile Met Gly Phe Ile Ser Lys Glu
                 575                 580                 585

 Arg Glu Arg Ala Leu Leu Lys Asp Gln Gln Pro Gly Thr Phe Leu
                 590                 595                 600

 Leu Arg Phe Ser Glu Ser Ser Arg Glu Gly Ala Ile Thr Phe Thr
                 605                 610                 615

 Trp Val Glu Arg Ser Gln Asn Gly Gly Glu Pro Asp Phe His Ala
                 620                 625                 630

 Val Glu Pro Tyr Thr Lys Lys Glu Leu Ser Ala Val Thr Phe Pro
                 635                 640                 645

 Asp Ile Ile Arg Asn Tyr Lys Val Met Ala Ala Glu Asn Ile Pro
                 650                 655                 660

 Glu Asn Pro Leu Lys Tyr Leu Tyr Pro Asn Ile Asp Lys Asp His
                 665                 670                 675

 Ala Phe Gly Lys Tyr Tyr Ser Arg Pro Lys Glu Ala Pro Glu Pro
                 680                 685                 690

 Met Glu Leu Asp Gly Pro Lys Gly Thr Gly Tyr Ile Lys Thr Glu
                 695                 700                 705

 Leu Ile Ser Val Ser Glu Val
                 710

<210> 2151
<211> 2224
<212> DNA
<213> Homo sapien

<400> 2151
 aaacttggac ctcatcctca attattttct cctttcaact ctgttgaccc 50

 tctgtctggt cttcctctag aaggttctac cgcagaaatt gatgtgtgct 100

 ccctgccctc gtcactgccc aagcccgggc ctgcacatac tcactggact 150

 gttccagttt tgacagctgc cagtcttcct gcccctttca cactgcagct 200

 gaagttcatt acctgaagga cgcctcatca tttcattcct tggctccaaa 250

 ccttctgctg cctctaagat aaaagctcaa cttcttaaca gtgtacagtg 300

 tgcaacttcc aaccttttta tctgttctct ccaccttcag tttagcgtca 350

 ttccaaaacc acacccttgc aaagctttgt actccgcacc ccagatgatc 400

 tccaggcagc tcagatctct ttcctgcctt tgccctgcac tgttccccgg 450

 tacttcctcc tttattgtag cactcagctc cccagccaat ctgtacatcc 500

 ctcagaggca gcgatctgat gaattggttt ttgaatccca gaaagggtct 550

 gccatggagt tggcagtcat cacggtagat ggcgtatgat tttgctgaat 600

 tttaaataaa atgaaaacca taaattacat gatgctttta ttgacacttg 650

 acaactggcc taaataaaaa gactctgact ctaatacaag tccccttact 700

 gataataggc atgaaagagc accattctta aaatctaaac cctttaaaat 750

 cagttacggc aattcactta aggagcttga gggccgtgtt aaaaggagcc 800

 aggttttcac aagacctcat ccacctctgc acattggctg gcactgtcac 850

 actgcagcct ccgatctgct ggagtacaga ccacagcacc acgtctgcta 900

 cggtgagttc attcccagcg agccaagggc tcttcccaag agcagagttc 950

 atggagcgga aaacagcggc tttttcttta ctgcttccct cttttaactg 1000

 aaaaatcgca atatctaccc agctatctat aagggttgcg ttgacagcat 1050

 tatgcttctg gccaaacaga gagaacaaga aacgtgcaat gttcccttcg 1100

 ccttcgatgg ggcacatcgt ctggatgctg aatttcatct gcgtcttcgg 1150

 cactgaaaag aaaaaacacg ccaggtagca tcaccagagc agccctgagg 1200

 gaagtactcg cacagtgggg aaggggacag tcaccaaaca ccacagactg 1250

 atgacatggg aaagggtgtt ttcaagaaga acatcacatt ttcagtctgt 1300

 ctctaagatg cttactactg aaaagggttt aagtgcaaac tatgttaaaa 1350

 agtaaccaaa gagtcattcc tggtatttga ttatgacact tctgaagcta 1400

 gaagggacct cagaccacct gctccaatcc ctgctgccta aggttttggg 1450

 ggctgagggc tggaaaccca ggagctgcat ctcccaggct cttggcctca 1500

 taatcgcctt ctgtgagact gagggcaatt aagatatgaa tgacatgaac 1550

 tcgcttctct ccatatcaac ataaaccaga agaggcatac atctgtggga 1600

 tagtcaatac ataacatcct atctttatat ggccatatga gaagataact 1650

 tcagtgtccc tatgatggta agttcttgaa tgtgagggca agatggctgt 1700

 gatagccatg actccccgct ttgcctggtt ggacagaacc cccttcccca 1750

 aatgctcaca gtccccccct tgagctgtgt ctcactcaga gaccctaaat 1800

 tttgcagacg aacaagggca tctttgcgtt gcttcatctc tgctcctcct 1850

 ctagaactat cccacaggct ttctagactt agaatatctg acctgatgca 1900

 aatcgctatg tggccagtat gccacagaat gtcctaaacc cttgctgcct 1950

 cttatcaaaa ccatgttgca catctcatca tatagtacag ctaacccttg 2000

 aacagtgggg gggttaggga cactgacccc cgactgctgt gcagtcgaaa 2050

 atccacataa aacttctgac tccttcaaaa cttaagcact aatagcctac 2100

 tattcatggg aagccttacc catcacagtt gattaacacg ttttgtatgg 2150

 tctgtatatt atatgctata ttcttacaat aaacttgaga aaatgttaag 2200

 aaaaaaaaaa aaaaaaaaaa aaaa 2224

<210> 2152
<211> 1216
<212> DNA
<213> Homo sapien

<400> 2152
 ggcagctgca cggctcctgg ccccggagca tgcgcgagag ccgccccgga 50

 gcgccccgga gccccccgcc gtcccgcccg cggcgtcccg cgccccgccg 100

 ccagcgcacc cccggacgct atggcccacc cctccggctg gccccttctg 150

 taggatggta gcacacaacc aggtggcagc cgacaatgca gtctccacag 200

 cagcagagcc ccgacggcgg ccagaacctt cctcctcttc ctcctcctcg 250

 cccgcggccc ccgcgcgccc gcggccgtgc cccgcggtcc cggccccggc 300

 ccccggcgac acgcacttcc gcacattccg ttcgcacgcc gattaccggc 350

 gcatcacgcg cgccagcgcg ctcctggacg cctgcggatt ctactggggg 400

 cccctgagcg tgcacggggc gcacgagcgg ctgcgcgccg agcccgtggg 450

 caccttcctg gtgcgcgaca gccgccagcg gaactgcttt ttcgccctta 500

 gcgtgaagat ggcctcggga cccacgagca tccgcgtgca ctttcaggcc 550

 ggccgctttc acctggatgg cagccgcgag agcttcgact gcctcttcga 600

 gctgctggag cactacgtgg cggcgccgcg ccgcatgctg ggggccccgc 650

 tgcgccagcg ccgcgtgcgg ccgctgcagg agctgtgccg ccagcgcatc 700

 gtggccaccg tgggccgcga gaacctggct cgcatccccc tcaaccccgt 750

 cctccgcgac tacctgagct ccttcccctt ccagatttga ccggcagcgc 800

 ccgccgtgca cgcagcatta actgggatgc cgtgttattt tgttattact 850

 tgcctggaac catgtgggta ccctccccgg cctgggttgg agggagcgga 900

 tgggtgtagg ggcgaggcgc ctcccgccct cggctggaga cgaggccgca 950

 gaccccttct cacctcttga gggggtcctc cccctcctgg tgctccctct 1000

 gggtccccct ggttgttgta gcagcttaac tgtatctgga gccaggacct 1050

 gaactcgcac ctcctacctc ttcatgttta catataccca gtatctttgc 1100

 acaaaccagg ggttggggga gggtctctgg ctttattttt ctgctgtgca 1150

 gaatcctatt ttatattttt taaagtcagt ttaggtaata aactttatta 1200

 tgaaagtttt tttttt 1216

<210> 2153
<211> 211
<212> PRT
<213> Homo sapien

<400> 2153
 Met Val Ala His Asn Gln Val Ala Ala Asp Asn Ala Val Ser Thr
   1               5                  10                  15

 Ala Ala Glu Pro Arg Arg Arg Pro Glu Pro Ser Ser Ser Ser Ser
                  20                  25                  30

 Ser Ser Pro Ala Ala Pro Ala Arg Pro Arg Pro Cys Pro Ala Val
                  35                  40                  45

 Pro Ala Pro Ala Pro Gly Asp Thr His Phe Arg Thr Phe Arg Ser
                  50                  55                  60

 His Ala Asp Tyr Arg Arg Ile Thr Arg Ala Ser Ala Leu Leu Asp
                  65                  70                  75

 Ala Cys Gly Phe Tyr Trp Gly Pro Leu Ser Val His Gly Ala His
                  80                  85                  90

 Glu Arg Leu Arg Ala Glu Pro Val Gly Thr Phe Leu Val Arg Asp
                  95                 100                 105

 Ser Arg Gln Arg Asn Cys Phe Phe Ala Leu Ser Val Lys Met Ala
                 110                 115                 120

 Ser Gly Pro Thr Ser Ile Arg Val His Phe Gln Ala Gly Arg Phe
                 125                 130                 135

 His Leu Asp Gly Ser Arg Glu Ser Phe Asp Cys Leu Phe Glu Leu
                 140                 145                 150

 Leu Glu His Tyr Val Ala Ala Pro Arg Arg Met Leu Gly Ala Pro
                 155                 160                 165

 Leu Arg Gln Arg Arg Val Arg Pro Leu Gln Glu Leu Cys Arg Gln
                 170                 175                 180

 Arg Ile Val Ala Thr Val Gly Arg Glu Asn Leu Ala Arg Ile Pro
                 185                 190                 195

 Leu Asn Pro Val Leu Arg Asp Tyr Leu Ser Ser Phe Pro Phe Gln
                 200                 205                 210

 Ile


<210> 2154
<211> 1216
<212> DNA
<213> Homo sapien

<400> 2154
 ggcagctgca cggctcctgg ccccggagca tgcgcgagag ccgccccgga 50

 gcgccccgga gccccccgcc gtcccgcccg cggcgtcccg cgccccgccg 100

 ccagcgcacc cccggacgct atggcccacc cctccggctg gccccttctg 150

 taggatggta gcacacaacc aggtggcagc cgacaatgca gtctccacag 200

 cagcagagcc ccgacggcgg ccagaacctt cctcctcttc ctcctcctcg 250

 cccgcggccc ccgcgcgccc gcggccgtgc cccgcggtcc cggccccggc 300

 ccccggcgac acgcacttcc gcacattccg ttcgcacgcc gattaccggc 350

 gcatcacgcg cgccagcgcg ctcctggacg cctgcggatt ctactggggg 400

 cccctgagcg tgcacggggc gcacgagcgg ctgcgcgccg agcccgtggg 450

 caccttcctg gtgcgcgaca gccgccagcg gaactgcttt ttcgccctta 500

 gcgtgaagat ggcctcggga cccacgagca tccgcgtgca ctttcaggcc 550

 ggccgctttc acctggatgg cagccgcgag agcttcgact gcctcttcga 600

 gctgctggag cactacgtgg cggcgccgcg ccgcatgctg ggggccccgc 650

 tgcgccagcg ccgcgtgcgg ccgctgcagg agctgtgccg ccagcgcatc 700

 gtggccaccg tgggccgcga gaacctggct cgcatccccc tcaaccccgt 750

 cctccgcgac tacctgagct ccttcccctt ccagatttga ccggcagcgc 800

 ccgccgtgca cgcagcatta actgggatgc cgtgttattt tgttattact 850

 tgcctggaac catgtgggta ccctccccgg cctgggttgg agggagcgga 900

 tgggtgtagg ggcgaggcgc ctcccgccct cggctggaga cgaggccgca 950

 gaccccttct cacctcttga gggggtcctc cccctcctgg tgctccctct 1000

 gggtccccct ggttgttgta gcagcttaac tgtatctgga gccaggacct 1050

 gaactcgcac ctcctacctc ttcatgttta catataccca gtatctttgc 1100

 acaaaccagg ggttggggga gggtctctgg ctttattttt ctgctgtgca 1150

 gaatcctatt ttatattttt taaagtcagt ttaggtaata aactttatta 1200

 tgaaagtttt tttttt 1216

<210> 2155
<211> 211
<212> PRT
<213> Homo sapien

<400> 2155
 Met Val Ala His Asn Gln Val Ala Ala Asp Asn Ala Val Ser Thr
   1               5                  10                  15

 Ala Ala Glu Pro Arg Arg Arg Pro Glu Pro Ser Ser Ser Ser Ser
                  20                  25                  30

 Ser Ser Pro Ala Ala Pro Ala Arg Pro Arg Pro Cys Pro Ala Val
                  35                  40                  45

 Pro Ala Pro Ala Pro Gly Asp Thr His Phe Arg Thr Phe Arg Ser
                  50                  55                  60

 His Ala Asp Tyr Arg Arg Ile Thr Arg Ala Ser Ala Leu Leu Asp
                  65                  70                  75

 Ala Cys Gly Phe Tyr Trp Gly Pro Leu Ser Val His Gly Ala His
                  80                  85                  90

 Glu Arg Leu Arg Ala Glu Pro Val Gly Thr Phe Leu Val Arg Asp
                  95                 100                 105

 Ser Arg Gln Arg Asn Cys Phe Phe Ala Leu Ser Val Lys Met Ala
                 110                 115                 120

 Ser Gly Pro Thr Ser Ile Arg Val His Phe Gln Ala Gly Arg Phe
                 125                 130                 135

 His Leu Asp Gly Ser Arg Glu Ser Phe Asp Cys Leu Phe Glu Leu
                 140                 145                 150

 Leu Glu His Tyr Val Ala Ala Pro Arg Arg Met Leu Gly Ala Pro
                 155                 160                 165

 Leu Arg Gln Arg Arg Val Arg Pro Leu Gln Glu Leu Cys Arg Gln
                 170                 175                 180

 Arg Ile Val Ala Thr Val Gly Arg Glu Asn Leu Ala Arg Ile Pro
                 185                 190                 195

 Leu Asn Pro Val Leu Arg Asp Tyr Leu Ser Ser Phe Pro Phe Gln
                 200                 205                 210

 Ile


<210> 2156
<211> 4996
<212> DNA
<213> Homo sapien

<400> 2156
 cgaggctccg tgccccgccc cccgggtgcc ccgccccttt gcgcggctgg 50

 cgcggccagc cggccaggct cccctcggca aacctgtcta attggggcgg 100

 ggagcggagc ttcctcctct gagggccgtg ccgcgctgcc agatttgttc 150

 ttccgcccct gcctccgcgg ctcggaggcg agcggaaggt gccccggggc 200

 cgaggcccgt gacggggcgg gcgggagccc cggcagtccg gggtcgccgg 250

 cgagggccat gtcgctgttg ggggacccgc tacaggccct gccgccctcg 300

 gccgccccca cggggccgct gctcgcccct ccggccggcg cgaccctcaa 350

 ccgcctgcgg gagccgctgc tgcggaggct cagcgagctc ctggatcagg 400

 cgcccgaggg ccggggctgg aggagactgg cggagctggc ggggagtcgc 450

 gggcgcctcc gcctcagttg cctagacctg gagcagtgtt ctcttaaggt 500

 actggagcct gaaggaagcc ccagcctgtg tctgctgaag ttaatgggtg 550

 aaaaaggttg cacagtcaca gaattgagtg atttcctgca ggctatggaa 600

 cacactgaag ttcttcagct tctcagcccc ccaggaataa agattactgt 650

 aaacccagag tcaaaggcag tcttggctgg acagtttgtg aaactgtgtt 700

 gccgggcaac tggacatcct tttgttcaat atcagtggtt caaaatgaat 750

 aaagagattc caaatggaaa tacatcagag cttattttta atgcagtgca 800

 tgtaaaagat gcaggctttt atgtctgtcg agttaataac aatttcacct 850

 ttgaattcag ccagtggtca cagctggatg tttgcgacat cccagagagc 900

 ttccagagaa gtgttgatgg cgtctctgaa tccaagttgc aaatctgtgt 950

 tgaaccaact tcccaaaagc tgatgccagg cagcacattg gttttacagt 1000

 gtgttgctgt tggaagccct attcctcact accagtggtt caaaaatgaa 1050

 ttaccattaa cacatgagac caaaaagcta tacatggtgc cttatgtgga 1100

 tttggaacac caaggaacct actggtgtca tgtatataat gatcgagaca 1150

 gtcaagatag caagaaggta gaaatcatca tagatgaatt aaataatctt 1200

 ggtcatcctg ataataaaga gcaaacaact gaccagcctt tggcgaagga 1250

 caaggttgcc cttttgatag gaaatatgaa ttaccgggag caccccaagc 1300

 tcaaagctcc tttggtggat gtgtacgaat tgactaactt actgagacag 1350

 ctggacttca aagtggtttc actgttggat cttactgaat atgagatgcg 1400

 taatgctgtg gatgagtttt tactcctttt agacaaggga gtatatgggt 1450

 tattatatta tgcaggacat ggttatgaaa attttgggaa cagcttcatg 1500

 gtccccgttg atgctccaaa tccatatagg tctgaaaatt gtctgtgtgt 1550

 acaaaatata ctgaaattga tgcaagaaaa agaaactgga cttaatgtgt 1600

 tcttattgga tatgtgtagg aaaagaaatg actacgatga taccattcca 1650

 atcttggatg cactaaaagt caccgccaat attgtgtttg gatatgccac 1700

 gtgtcaagga gcagaagctt ttgaaatcca gcattctgga ttggcaaatg 1750

 gaatctttat gaaattttta aaagacagat tattagaaga taagaaaatc 1800

 actgtgttac tggatgaagt tgcagaagat atgggtaagt gtcaccttac 1850

 caaaggcaaa caggctctag agattcgaag tagtttatct gagaagagag 1900

 cacttactga tccaatacag ggaacagaat attctgctga atctcttgtg 1950

 cggaatctac agtgggccaa ggctcatgaa cttccagaaa gtatgtgtct 2000

 taagtttgac tgtggtgttc agattcaatt aggatttgca gctgagtttt 2050

 ccaatgtcat gatcatctat acaagtatag tttacaaacc accggagata 2100

 ataatgtgtg atgcctacgt tactgatttt ccacttgatc tagatattga 2150

 tccaaaagat gcaaataaag gcacacctga agaaactggc agctacttgg 2200

 tatcaaagga tcttcccaag cattgcctct ataccagact cagttcactg 2250

 caaaaattaa aggaacatct agtcttcaca gtatgtttat catatcagta 2300

 ctcaggattg gaagatactg tagaggacaa gcaggaagtg aatgttggga 2350

 aacctctcat tgctaaatta gacatgcatc gaggtttggg aaggaagact 2400

 tgctttcaaa cttgtcttat gtctaatggt ccttaccaga gttctgcagc 2450

 cacctcagga ggagcagggc attatcactc attgcaagac ccattccatg 2500

 gtgtttacca ttcacatcct ggtaatccaa gtaatgttac accagcagat 2550

 agctgtcatt gcagccggac tccagatgca tttatttcaa gtttcgctca 2600

 ccatgcttca tgtcatttta gtagaagtaa tgtgccagta gagacaactg 2650

 atgaaatacc atttagtttc tctgacaggc tcagaatttc tgaaaaatga 2700

 cctccttgtt tttgaaagtt agcataattt tagatgcctg tgaaatagta 2750

 ctgcacttac ataaagtgag acattgtgaa aaggcaaatt tgtatatgta 2800

 gagaaagaat agtagtaact gtttcatagc aaacttcagg actttgagat 2850

 gttgaaatta cattatttaa ttacagactt cctctttcta agattttgtg 2900

 aattggttga atagttctat acaaatgaag tatggaggtg tgtatgttta 2950

 tatgtatata acaaaatatt ttcattgtga ccactctgaa gtaagagcaa 3000

 tgggaatggc attattgtag aataagtcat tgtattttta acaccagaaa 3050

 gaaccttgcc gatcaccagg cataacctaa ttttatccat ggaagaaaca 3100

 cagaaaggca tctaagttag agctggcacc agaactgaga cctccagaaa 3150

 tctattccag tattttttcc actacacaac tgccttcctg acaggttctg 3200

 agataagtgt tatgtttgta gatagagtga aatatattta tatatatata 3250

 aatatataca gatacatatc tgtgtattat ctcaaggaat gtacaaactt 3300

 tagtttttga ttataaggac ttcactgcaa gttttagtta agaggtttgt 3350

 atataaatct gttatagaac aggctgaaat ttcttgttca taagattatg 3400

 aaaccacatg agaagtgata aaatgtttgt taaagctaga tagaggttaa 3450

 gaatcaagat ataatggata attttcatag ctgcctatca gaatttccca 3500

 aatatttagc atcttccttg ataatatgta ttttcttctt gaatttcact 3550

 ggcctaatga gataatactc ttatctttgg ctctacctaa aagttggtta 3600

 aaaatgcaat tggcattaac aaggaaaaat actgaattag taattttaaa 3650

 agtctcacaa agaaaatccc aggcctagat ggctgcattg ttgaattctg 3700

 ccaaacatta aaattagcac taattttttg cacactgttt ctaaaagtag 3750

 gagaggaaag aacacttccc aacttactct aggtcagtat taccctgata 3800

 ctagactaga catcacaaga aaactataag ccaatattcc ttattaatac 3850

 aaacacaaaa atcattaaca aaaatattag caaactgaat ccagcaacct 3900

 ataaaaagga ttctatatca tgaccaagtg gaatttatcc caggaattca 3950

 aggttggttc aacatctaaa aatcaaataa gctaatatac agtcagttct 4000

 cattattcac agtaattatg ttctacagaa tattctccca taaacactga 4050

 attaaatatg gaacaactgc ttttaggaga aagtgtattt gtgtatatgt 4100

 gtgtatacat atgtttatct cacacacatt atgagcttga attcttaatt 4150

 catcctagca aattctacct tattttacag aagtgaaagt gaggtatcag 4200

 aagtgttaag tgacatgcct gaggcacccc cctaacaggt gtcagagctg 4250

 aaattcaaac cccatccagc tggccccgga gccagagctt cttgtactac 4300

 acagaattgc ccctgccatt tccaccctcc agtcatttct ctatgagact 4350

 gaagcaggaa ggcagagcat catcttgttc agcctcagct gggaacatgt 4400

 gtactgggtg actcaaattt ttcacccatt tacacatatc cacaaatgac 4450

 tgcaaaagtg ccacggatat caatttgagg gttataaatt ttagcaagtt 4500

 ggtaaattca caaatacata accttgaata atgaggatca actgtaccat 4550

 atttaataaa gcacaaaacc cacacagatt gtcttattac agcatttgat 4600

 aaaatccaaa actctttcat aaaaacactc aacaaactta ggaataaaag 4650

 gaatcttcct agatatgata aatataacat ctatgaaaag cccacaccta 4700

 acattatact tcatggtgat agactgaagg ctgaatgttt tccccttaag 4750

 attgggaaga aggacaagga tgttcactcg gcactacttc tattcagcat 4800

 tgtacttgaa gttctagcca cagcagttag gttaggaatt caaggtttgt 4850

 tcaacatcta aaaatcaaat aagctaataa agaaaagagg tttatactgc 4900

 aaaagaagtg aaactatatg tattcacagt tgatacatag ttgtatatag 4950

 aaaatgctaa agaatccata aaaagtaata aatgagttca acaggt 4996

<210> 2157
<211> 813
<212> PRT
<213> Homo sapien

<400> 2157
 Met Ser Leu Leu Gly Asp Pro Leu Gln Ala Leu Pro Pro Ser Ala
   1               5                  10                  15

 Ala Pro Thr Gly Pro Leu Leu Ala Pro Pro Ala Gly Ala Thr Leu
                  20                  25                  30

 Asn Arg Leu Arg Glu Pro Leu Leu Arg Arg Leu Ser Glu Leu Leu
                  35                  40                  45

 Asp Gln Ala Pro Glu Gly Arg Gly Trp Arg Arg Leu Ala Glu Leu
                  50                  55                  60

 Ala Gly Ser Arg Gly Arg Leu Arg Leu Ser Cys Leu Asp Leu Glu
                  65                  70                  75

 Gln Cys Ser Leu Lys Val Leu Glu Pro Glu Gly Ser Pro Ser Leu
                  80                  85                  90

 Cys Leu Leu Lys Leu Met Gly Glu Lys Gly Cys Thr Val Thr Glu
                  95                 100                 105

 Leu Ser Asp Phe Leu Gln Ala Met Glu His Thr Glu Val Leu Gln
                 110                 115                 120

 Leu Leu Ser Pro Pro Gly Ile Lys Ile Thr Val Asn Pro Glu Ser
                 125                 130                 135

 Lys Ala Val Leu Ala Gly Gln Phe Val Lys Leu Cys Cys Arg Ala
                 140                 145                 150

 Thr Gly His Pro Phe Val Gln Tyr Gln Trp Phe Lys Met Asn Lys
                 155                 160                 165

 Glu Ile Pro Asn Gly Asn Thr Ser Glu Leu Ile Phe Asn Ala Val
                 170                 175                 180

 His Val Lys Asp Ala Gly Phe Tyr Val Cys Arg Val Asn Asn Asn
                 185                 190                 195

 Phe Thr Phe Glu Phe Ser Gln Trp Ser Gln Leu Asp Val Cys Asp
                 200                 205                 210

 Ile Pro Glu Ser Phe Gln Arg Ser Val Asp Gly Val Ser Glu Ser
                 215                 220                 225

 Lys Leu Gln Ile Cys Val Glu Pro Thr Ser Gln Lys Leu Met Pro
                 230                 235                 240

 Gly Ser Thr Leu Val Leu Gln Cys Val Ala Val Gly Ser Pro Ile
                 245                 250                 255

 Pro His Tyr Gln Trp Phe Lys Asn Glu Leu Pro Leu Thr His Glu
                 260                 265                 270

 Thr Lys Lys Leu Tyr Met Val Pro Tyr Val Asp Leu Glu His Gln
                 275                 280                 285

 Gly Thr Tyr Trp Cys His Val Tyr Asn Asp Arg Asp Ser Gln Asp
                 290                 295                 300

 Ser Lys Lys Val Glu Ile Ile Ile Asp Glu Leu Asn Asn Leu Gly
                 305                 310                 315

 His Pro Asp Asn Lys Glu Gln Thr Thr Asp Gln Pro Leu Ala Lys
                 320                 325                 330

 Asp Lys Val Ala Leu Leu Ile Gly Asn Met Asn Tyr Arg Glu His
                 335                 340                 345

 Pro Lys Leu Lys Ala Pro Leu Val Asp Val Tyr Glu Leu Thr Asn
                 350                 355                 360

 Leu Leu Arg Gln Leu Asp Phe Lys Val Val Ser Leu Leu Asp Leu
                 365                 370                 375

 Thr Glu Tyr Glu Met Arg Asn Ala Val Asp Glu Phe Leu Leu Leu
                 380                 385                 390

 Leu Asp Lys Gly Val Tyr Gly Leu Leu Tyr Tyr Ala Gly His Gly
                 395                 400                 405

 Tyr Glu Asn Phe Gly Asn Ser Phe Met Val Pro Val Asp Ala Pro
                 410                 415                 420

 Asn Pro Tyr Arg Ser Glu Asn Cys Leu Cys Val Gln Asn Ile Leu
                 425                 430                 435

 Lys Leu Met Gln Glu Lys Glu Thr Gly Leu Asn Val Phe Leu Leu
                 440                 445                 450

 Asp Met Cys Arg Lys Arg Asn Asp Tyr Asp Asp Thr Ile Pro Ile
                 455                 460                 465

 Leu Asp Ala Leu Lys Val Thr Ala Asn Ile Val Phe Gly Tyr Ala
                 470                 475                 480

 Thr Cys Gln Gly Ala Glu Ala Phe Glu Ile Gln His Ser Gly Leu
                 485                 490                 495

 Ala Asn Gly Ile Phe Met Lys Phe Leu Lys Asp Arg Leu Leu Glu
                 500                 505                 510

 Asp Lys Lys Ile Thr Val Leu Leu Asp Glu Val Ala Glu Asp Met
                 515                 520                 525

 Gly Lys Cys His Leu Thr Lys Gly Lys Gln Ala Leu Glu Ile Arg
                 530                 535                 540

 Ser Ser Leu Ser Glu Lys Arg Ala Leu Thr Asp Pro Ile Gln Gly
                 545                 550                 555

 Thr Glu Tyr Ser Ala Glu Ser Leu Val Arg Asn Leu Gln Trp Ala
                 560                 565                 570

 Lys Ala His Glu Leu Pro Glu Ser Met Cys Leu Lys Phe Asp Cys
                 575                 580                 585

 Gly Val Gln Ile Gln Leu Gly Phe Ala Ala Glu Phe Ser Asn Val
                 590                 595                 600

 Met Ile Ile Tyr Thr Ser Ile Val Tyr Lys Pro Pro Glu Ile Ile
                 605                 610                 615

 Met Cys Asp Ala Tyr Val Thr Asp Phe Pro Leu Asp Leu Asp Ile
                 620                 625                 630

 Asp Pro Lys Asp Ala Asn Lys Gly Thr Pro Glu Glu Thr Gly Ser
                 635                 640                 645

 Tyr Leu Val Ser Lys Asp Leu Pro Lys His Cys Leu Tyr Thr Arg
                 650                 655                 660

 Leu Ser Ser Leu Gln Lys Leu Lys Glu His Leu Val Phe Thr Val
                 665                 670                 675

 Cys Leu Ser Tyr Gln Tyr Ser Gly Leu Glu Asp Thr Val Glu Asp
                 680                 685                 690

 Lys Gln Glu Val Asn Val Gly Lys Pro Leu Ile Ala Lys Leu Asp
                 695                 700                 705

 Met His Arg Gly Leu Gly Arg Lys Thr Cys Phe Gln Thr Cys Leu
                 710                 715                 720

 Met Ser Asn Gly Pro Tyr Gln Ser Ser Ala Ala Thr Ser Gly Gly
                 725                 730                 735

 Ala Gly His Tyr His Ser Leu Gln Asp Pro Phe His Gly Val Tyr
                 740                 745                 750

 His Ser His Pro Gly Asn Pro Ser Asn Val Thr Pro Ala Asp Ser
                 755                 760                 765

 Cys His Cys Ser Arg Thr Pro Asp Ala Phe Ile Ser Ser Phe Ala
                 770                 775                 780

 His His Ala Ser Cys His Phe Ser Arg Ser Asn Val Pro Val Glu
                 785                 790                 795

 Thr Thr Asp Glu Ile Pro Phe Ser Phe Ser Asp Arg Leu Arg Ile
                 800                 805                 810

 Ser Glu Lys


<210> 2158
<211> 5029
<212> DNA
<213> Homo sapien

<400> 2158
 cgaggctccg tgccccgccc cccgggtgcc ccgccccttt gcgcggctgg 50

 cgcggccagc cggccaggct cccctcggca aacctgtcta attggggcgg 100

 ggagcggagc ttcctcctct gagggccgtg ccgcgctgcc agatttgttc 150

 ttccgcccct gcctccgcgg ctcggaggcg agcggaaggt gccccggggc 200

 cgaggcccgt gacggggcgg gcgggagccc cggcagtccg gggtcgccgg 250

 cgagggccat gtcgctgttg ggggacccgc tacaggccct gccgccctcg 300

 gccgccccca cggggccgct gctcgcccct ccggccggcg cgaccctcaa 350

 ccgcctgcgg gagccgctgc tgcggaggct cagcgagctc ctggatcagg 400

 cgcccgaggg ccggggctgg aggagactgg cggagctggc ggggagtcgc 450

 gggcgcctcc gcctcagttg cctagacctg gagcagtgtt ctcttaaggt 500

 actggagcct gaaggaagcc ccagcctgtg tctgctgaag ttaatgggtg 550

 aaaaaggttg cacagtcaca gaattgagtg atttcctgca ggctatggaa 600

 cacactgaag ttcttcagct tctcagcccc ccaggaataa agattactgt 650

 aaacccagag tcaaaggcag tcttggctgg acagtttgtg aaactgtgtt 700

 gccgggcaac tggacatcct tttgttcaat atcagtggtt caaaatgaat 750

 aaagagattc caaatggaaa tacatcagag cttattttta atgcagtgca 800

 tgtaaaagat gcaggctttt atgtctgtcg agttaataac aatttcacct 850

 ttgaattcag ccagtggtca cagctggatg tttgcgacat cccagagagc 900

 ttccagagaa gtgttgatgg cgtctctgaa tccaagttgc aaatctgtgt 950

 tgaaccaact tcccaaaagc tgatgccagg cagcacattg gttttacagt 1000

 gtgttgctgt tggaagccct attcctcact accagtggtt caaaaatgaa 1050

 ttaccattaa cacatgagac caaaaagcta tacatggtgc cttatgtgga 1100

 tttggaacac caaggaacct actggtgtca tgtatataat gatcgagaca 1150

 gtcaagatag caagaaggta gaaatcatca taggaagaac agatgaggca 1200

 gtggagtgca ctgaagatga attaaataat cttggtcatc ctgataataa 1250

 agagcaaaca actgaccagc ctttggcgaa ggacaaggtt gcccttttga 1300

 taggaaatat gaattaccgg gagcacccca agctcaaagc tcctttggtg 1350

 gatgtgtacg aattgactaa cttactgaga cagctggact tcaaagtggt 1400

 ttcactgttg gatcttactg aatatgagat gcgtaatgct gtggatgagt 1450

 ttttactcct tttagacaag ggagtatatg ggttattata ttatgcagga 1500

 catggttatg aaaattttgg gaacagcttc atggtccccg ttgatgctcc 1550

 aaatccatat aggtctgaaa attgtctgtg tgtacaaaat atactgaaat 1600

 tgatgcaaga aaaagaaact ggacttaatg tgttcttatt ggatatgtgt 1650

 aggaaaagaa atgactacga tgataccatt ccaatcttgg atgcactaaa 1700

 agtcaccgcc aatattgtgt ttggatatgc cacgtgtcaa ggagcagaag 1750

 cttttgaaat ccagcattct ggattggcaa atggaatctt tatgaaattt 1800

 ttaaaagaca gattattaga agataagaaa atcactgtgt tactggatga 1850

 agttgcagaa gatatgggta agtgtcacct taccaaaggc aaacaggctc 1900

 tagagattcg aagtagttta tctgagaaga gagcacttac tgatccaata 1950

 cagggaacag aatattctgc tgaatctctt gtgcggaatc tacagtgggc 2000

 caaggctcat gaacttccag aaagtatgtg tcttaagttt gactgtggtg 2050

 ttcagattca attaggattt gcagctgagt tttccaatgt catgatcatc 2100

 tatacaagta tagtttacaa accaccggag ataataatgt gtgatgccta 2150

 cgttactgat tttccacttg atctagatat tgatccaaaa gatgcaaata 2200

 aaggcacacc tgaagaaact ggcagctact tggtatcaaa ggatcttccc 2250

 aagcattgcc tctataccag actcagttca ctgcaaaaat taaaggaaca 2300

 tctagtcttc acagtatgtt tatcatatca gtactcagga ttggaagata 2350

 ctgtagagga caagcaggaa gtgaatgttg ggaaacctct cattgctaaa 2400

 ttagacatgc atcgaggttt gggaaggaag acttgctttc aaacttgtct 2450

 tatgtctaat ggtccttacc agagttctgc agccacctca ggaggagcag 2500

 ggcattatca ctcattgcaa gacccattcc atggtgttta ccattcacat 2550

 cctggtaatc caagtaatgt tacaccagca gatagctgtc attgcagccg 2600

 gactccagat gcatttattt caagtttcgc tcaccatgct tcatgtcatt 2650

 ttagtagaag taatgtgcca gtagagacaa ctgatgaaat accatttagt 2700

 ttctctgaca ggctcagaat ttctgaaaaa tgacctcctt gtttttgaaa 2750

 gttagcataa ttttagatgc ctgtgaaata gtactgcact tacataaagt 2800

 gagacattgt gaaaaggcaa atttgtatat gtagagaaag aatagtagta 2850

 actgtttcat agcaaacttc aggactttga gatgttgaaa ttacattatt 2900

 taattacaga cttcctcttt ctaagatttt gtgaattggt tgaatagttc 2950

 tatacaaatg aagtatggag gtgtgtatgt ttatatgtat ataacaaaat 3000

 attttcattg tgaccactct gaagtaagag caatgggaat ggcattattg 3050

 tagaataagt cattgtattt ttaacaccag aaagaacctt gccgatcacc 3100

 aggcataacc taattttatc catggaagaa acacagaaag gcatctaagt 3150

 tagagctggc accagaactg agacctccag aaatctattc cagtattttt 3200

 tccactacac aactgccttc ctgacaggtt ctgagataag tgttatgttt 3250

 gtagatagag tgaaatatat ttatatatat ataaatatat acagatacat 3300

 atctgtgtat tatctcaagg aatgtacaaa ctttagtttt tgattataag 3350

 gacttcactg caagttttag ttaagaggtt tgtatataaa tctgttatag 3400

 aacaggctga aatttcttgt tcataagatt atgaaaccac atgagaagtg 3450

 ataaaatgtt tgttaaagct agatagaggt taagaatcaa gatataatgg 3500

 ataattttca tagctgccta tcagaatttc ccaaatattt agcatcttcc 3550

 ttgataatat gtattttctt cttgaatttc actggcctaa tgagataata 3600

 ctcttatctt tggctctacc taaaagttgg ttaaaaatgc aattggcatt 3650

 aacaaggaaa aatactgaat tagtaatttt aaaagtctca caaagaaaat 3700

 cccaggccta gatggctgca ttgttgaatt ctgccaaaca ttaaaattag 3750

 cactaatttt ttgcacactg tttctaaaag taggagagga aagaacactt 3800

 cccaacttac tctaggtcag tattaccctg atactagact agacatcaca 3850

 agaaaactat aagccaatat tccttattaa tacaaacaca aaaatcatta 3900

 acaaaaatat tagcaaactg aatccagcaa cctataaaaa ggattctata 3950

 tcatgaccaa gtggaattta tcccaggaat tcaaggttgg ttcaacatct 4000

 aaaaatcaaa taagctaata tacagtcagt tctcattatt cacagtaatt 4050

 atgttctaca gaatattctc ccataaacac tgaattaaat atggaacaac 4100

 tgcttttagg agaaagtgta tttgtgtata tgtgtgtata catatgttta 4150

 tctcacacac attatgagct tgaattctta attcatccta gcaaattcta 4200

 ccttatttta cagaagtgaa agtgaggtat cagaagtgtt aagtgacatg 4250

 cctgaggcac ccccctaaca ggtgtcagag ctgaaattca aaccccatcc 4300

 agctggcccc ggagccagag cttcttgtac tacacagaat tgcccctgcc 4350

 atttccaccc tccagtcatt tctctatgag actgaagcag gaaggcagag 4400

 catcatcttg ttcagcctca gctgggaaca tgtgtactgg gtgactcaaa 4450

 tttttcaccc atttacacat atccacaaat gactgcaaaa gtgccacgga 4500

 tatcaatttg agggttataa attttagcaa gttggtaaat tcacaaatac 4550

 ataaccttga ataatgagga tcaactgtac catatttaat aaagcacaaa 4600

 acccacacag attgtcttat tacagcattt gataaaatcc aaaactcttt 4650

 cataaaaaca ctcaacaaac ttaggaataa aaggaatctt cctagatatg 4700

 ataaatataa catctatgaa aagcccacac ctaacattat acttcatggt 4750

 gatagactga aggctgaatg ttttcccctt aagattggga agaaggacaa 4800

 ggatgttcac tcggcactac ttctattcag cattgtactt gaagttctag 4850

 ccacagcagt taggttagga attcaaggtt tgttcaacat ctaaaaatca 4900

 aataagctaa taaagaaaag aggtttatac tgcaaaagaa gtgaaactat 4950

 atgtattcac agttgataca tagttgtata tagaaaatgc taaagaatcc 5000

 ataaaaagta ataaatgagt tcaacaggt 5029

<210> 2159
<211> 824
<212> PRT
<213> Homo sapien

<400> 2159
 Met Ser Leu Leu Gly Asp Pro Leu Gln Ala Leu Pro Pro Ser Ala
   1               5                  10                  15

 Ala Pro Thr Gly Pro Leu Leu Ala Pro Pro Ala Gly Ala Thr Leu
                  20                  25                  30

 Asn Arg Leu Arg Glu Pro Leu Leu Arg Arg Leu Ser Glu Leu Leu
                  35                  40                  45

 Asp Gln Ala Pro Glu Gly Arg Gly Trp Arg Arg Leu Ala Glu Leu
                  50                  55                  60

 Ala Gly Ser Arg Gly Arg Leu Arg Leu Ser Cys Leu Asp Leu Glu
                  65                  70                  75

 Gln Cys Ser Leu Lys Val Leu Glu Pro Glu Gly Ser Pro Ser Leu
                  80                  85                  90

 Cys Leu Leu Lys Leu Met Gly Glu Lys Gly Cys Thr Val Thr Glu
                  95                 100                 105

 Leu Ser Asp Phe Leu Gln Ala Met Glu His Thr Glu Val Leu Gln
                 110                 115                 120

 Leu Leu Ser Pro Pro Gly Ile Lys Ile Thr Val Asn Pro Glu Ser
                 125                 130                 135

 Lys Ala Val Leu Ala Gly Gln Phe Val Lys Leu Cys Cys Arg Ala
                 140                 145                 150

 Thr Gly His Pro Phe Val Gln Tyr Gln Trp Phe Lys Met Asn Lys
                 155                 160                 165

 Glu Ile Pro Asn Gly Asn Thr Ser Glu Leu Ile Phe Asn Ala Val
                 170                 175                 180

 His Val Lys Asp Ala Gly Phe Tyr Val Cys Arg Val Asn Asn Asn
                 185                 190                 195

 Phe Thr Phe Glu Phe Ser Gln Trp Ser Gln Leu Asp Val Cys Asp
                 200                 205                 210

 Ile Pro Glu Ser Phe Gln Arg Ser Val Asp Gly Val Ser Glu Ser
                 215                 220                 225

 Lys Leu Gln Ile Cys Val Glu Pro Thr Ser Gln Lys Leu Met Pro
                 230                 235                 240

 Gly Ser Thr Leu Val Leu Gln Cys Val Ala Val Gly Ser Pro Ile
                 245                 250                 255

 Pro His Tyr Gln Trp Phe Lys Asn Glu Leu Pro Leu Thr His Glu
                 260                 265                 270

 Thr Lys Lys Leu Tyr Met Val Pro Tyr Val Asp Leu Glu His Gln
                 275                 280                 285

 Gly Thr Tyr Trp Cys His Val Tyr Asn Asp Arg Asp Ser Gln Asp
                 290                 295                 300

 Ser Lys Lys Val Glu Ile Ile Ile Gly Arg Thr Asp Glu Ala Val
                 305                 310                 315

 Glu Cys Thr Glu Asp Glu Leu Asn Asn Leu Gly His Pro Asp Asn
                 320                 325                 330

 Lys Glu Gln Thr Thr Asp Gln Pro Leu Ala Lys Asp Lys Val Ala
                 335                 340                 345

 Leu Leu Ile Gly Asn Met Asn Tyr Arg Glu His Pro Lys Leu Lys
                 350                 355                 360

 Ala Pro Leu Val Asp Val Tyr Glu Leu Thr Asn Leu Leu Arg Gln
                 365                 370                 375

 Leu Asp Phe Lys Val Val Ser Leu Leu Asp Leu Thr Glu Tyr Glu
                 380                 385                 390

 Met Arg Asn Ala Val Asp Glu Phe Leu Leu Leu Leu Asp Lys Gly
                 395                 400                 405

 Val Tyr Gly Leu Leu Tyr Tyr Ala Gly His Gly Tyr Glu Asn Phe
                 410                 415                 420

 Gly Asn Ser Phe Met Val Pro Val Asp Ala Pro Asn Pro Tyr Arg
                 425                 430                 435

 Ser Glu Asn Cys Leu Cys Val Gln Asn Ile Leu Lys Leu Met Gln
                 440                 445                 450

 Glu Lys Glu Thr Gly Leu Asn Val Phe Leu Leu Asp Met Cys Arg
                 455                 460                 465

 Lys Arg Asn Asp Tyr Asp Asp Thr Ile Pro Ile Leu Asp Ala Leu
                 470                 475                 480

 Lys Val Thr Ala Asn Ile Val Phe Gly Tyr Ala Thr Cys Gln Gly
                 485                 490                 495

 Ala Glu Ala Phe Glu Ile Gln His Ser Gly Leu Ala Asn Gly Ile
                 500                 505                 510

 Phe Met Lys Phe Leu Lys Asp Arg Leu Leu Glu Asp Lys Lys Ile
                 515                 520                 525

 Thr Val Leu Leu Asp Glu Val Ala Glu Asp Met Gly Lys Cys His
                 530                 535                 540

 Leu Thr Lys Gly Lys Gln Ala Leu Glu Ile Arg Ser Ser Leu Ser
                 545                 550                 555

 Glu Lys Arg Ala Leu Thr Asp Pro Ile Gln Gly Thr Glu Tyr Ser
                 560                 565                 570

 Ala Glu Ser Leu Val Arg Asn Leu Gln Trp Ala Lys Ala His Glu
                 575                 580                 585

 Leu Pro Glu Ser Met Cys Leu Lys Phe Asp Cys Gly Val Gln Ile
                 590                 595                 600

 Gln Leu Gly Phe Ala Ala Glu Phe Ser Asn Val Met Ile Ile Tyr
                 605                 610                 615

 Thr Ser Ile Val Tyr Lys Pro Pro Glu Ile Ile Met Cys Asp Ala
                 620                 625                 630

 Tyr Val Thr Asp Phe Pro Leu Asp Leu Asp Ile Asp Pro Lys Asp
                 635                 640                 645

 Ala Asn Lys Gly Thr Pro Glu Glu Thr Gly Ser Tyr Leu Val Ser
                 650                 655                 660

 Lys Asp Leu Pro Lys His Cys Leu Tyr Thr Arg Leu Ser Ser Leu
                 665                 670                 675

 Gln Lys Leu Lys Glu His Leu Val Phe Thr Val Cys Leu Ser Tyr
                 680                 685                 690

 Gln Tyr Ser Gly Leu Glu Asp Thr Val Glu Asp Lys Gln Glu Val
                 695                 700                 705

 Asn Val Gly Lys Pro Leu Ile Ala Lys Leu Asp Met His Arg Gly
                 710                 715                 720

 Leu Gly Arg Lys Thr Cys Phe Gln Thr Cys Leu Met Ser Asn Gly
                 725                 730                 735

 Pro Tyr Gln Ser Ser Ala Ala Thr Ser Gly Gly Ala Gly His Tyr
                 740                 745                 750

 His Ser Leu Gln Asp Pro Phe His Gly Val Tyr His Ser His Pro
                 755                 760                 765

 Gly Asn Pro Ser Asn Val Thr Pro Ala Asp Ser Cys His Cys Ser
                 770                 775                 780

 Arg Thr Pro Asp Ala Phe Ile Ser Ser Phe Ala His His Ala Ser
                 785                 790                 795

 Cys His Phe Ser Arg Ser Asn Val Pro Val Glu Thr Thr Asp Glu
                 800                 805                 810

 Ile Pro Phe Ser Phe Ser Asp Arg Leu Arg Ile Ser Glu Lys
                 815                 820

<210> 2160
<211> 1723
<212> DNA
<213> Homo sapien

<400> 2160
 gggggagtgc gaatttcttg gcctgtcggc aggtgctttc tcaaaggccc 50

 cacagtcctc cacttcctgg ggaggtagct gcagaataaa accagcagag 100

 actccttttc tcctaaccgt cccggccacc gctgcctcag cctctgcctc 150

 ccagcctctt tctgagggaa aggacaagat gaagtggaag gcgcttttca 200

 ccgcggccat cctgcaggca cagttgccga ttacagaggc acagagcttt 250

 ggcctgctgg atcccaaact ctgctacctg ctggatggaa tcctcttcat 300

 ctatggtgtc attctcactg ccttgttcct gagagtgaag ttcagcagga 350

 gcgcagacgc ccccgcgtac cagcagggcc agaaccagct ctataacgag 400

 ctcaatctag gacgaagaga ggagtacgat gttttggaca agagacgtgg 450

 ccgggaccct gagatggggg gaaagccgag aaggaagaac cctcaggaag 500

 gcctgtacaa tgaactgcag aaagataaga tggcggaggc ctacagtgag 550

 attgggatga aaggcgagcg ccggaggggc aaggggcacg atggccttta 600

 ccagggtctc agtacagcca ccaaggacac ctacgacgcc cttcacatgc 650

 aggccctgcc ccctcgctaa cagccagggg atttcaccac tcaaaggcca 700

 gacctgcaga cgcccagatt atgagacaca ggatgaagca tttacaaccc 750

 ggttcactct tctcagccac tgaagtattc ccctttatgt acaggatgct 800

 ttggttatat ttagctccaa accttcacac acagactgtt gtccctgcac 850

 tctttaaggg agtgtactcc cagggcttac ggccctgcct tgggccctct 900

 ggtttgccgg tggtgcaggt agacctgtct cctggcggtt cctcgttctc 950

 cctgggaggc gggcgcactg cctctcacag ctgagttgtt gagtctgttt 1000

 tgtaaagtcc ccagagaaag cgcagatgct agcacatgcc ctaatgtctg 1050

 tatcactctg tgtctgagtg gcttcactcc tgctgtaaat ttggcttctg 1100

 ttgtcacctt cacctccttt caaggtaact gtactgggcc atgttgtgcc 1150

 tccctggtga gagggccggg cagaggggca gatggaaagg agcctaggcc 1200

 aggtgcaacc agggagctgc aggggcatgg gaaggtgggc gggcagggga 1250

 gggtcagcca gggcctgcga gggcagcggg agcctccctg cctcaggcct 1300

 ctgtgccgca ccattgaact gtaccatgtg ctacaggggc cagaagatga 1350

 acagactgac cttgatgagc tgtgcacaaa gtggcataaa aaacagtgtg 1400

 gttacacagt gtgaataaag tgctgcggag caagaggagg ccgttgattc 1450

 acttcacgct ttcagcgaat gacaaaatca tctttgtgaa ggcctcgcag 1500

 gaagacgcaa cacatgggac ctataactgc ccagcggaca gtggcaggac 1550

 aggaaaaacc cgtcaatgta ctagggtact gctgcgtcat tacagggcac 1600

 aggccatgga tggaaaacgc tctctgctct gctttttttc tactgtttta 1650

 atttatactg gcatgctatt gccttcctat tttgcataat aaatgcttca 1700

 gtgaaaatgc agctttactc taa 1723

<210> 2161
<211> 163
<212> PRT
<213> Homo sapien

<400> 2161
 Met Lys Trp Lys Ala Leu Phe Thr Ala Ala Ile Leu Gln Ala Gln
   1               5                  10                  15

 Leu Pro Ile Thr Glu Ala Gln Ser Phe Gly Leu Leu Asp Pro Lys
                  20                  25                  30

 Leu Cys Tyr Leu Leu Asp Gly Ile Leu Phe Ile Tyr Gly Val Ile
                  35                  40                  45

 Leu Thr Ala Leu Phe Leu Arg Val Lys Phe Ser Arg Ser Ala Asp
                  50                  55                  60

 Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu
                  65                  70                  75

 Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg
                  80                  85                  90

 Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro
                  95                 100                 105

 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu
                 110                 115                 120

 Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys
                 125                 130                 135

 Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp
                 140                 145                 150

 Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg
                 155                 160

<210> 2162
<211> 1740
<212> DNA
<213> Homo sapien

<400> 2162
 ccagcgttag cccgcggcca ggcagccggg aggagcggcg cgcgctcgga 50

 cctctcccgc cctgctcgtt cgctctccag cttgggatgg ccggctacct 100

 gcgggtcgtg cgctcgctct gcagagcctc aggctcgcgg ccggcctggg 150

 cgccggcggc cctgacagcc cccacctcgc aagagcagcc gcggcgccac 200

 tatgccgaca aaaggatcaa ggtggcgaag cccgtggtgg agatggatgg 250

 tgatgagatg acccgtatta tctggcagtt catcaaggag aagctcatcc 300

 tgccccacgt ggacatccag ctaaagtatt ttgacctcgg gctcccaaac 350

 cgtgaccaga ctgatgacca ggtcaccatt gactctgcac tggccaccca 400

 gaagtacagt gtggctgtca agtgtgccac catcacccct gatgaggccc 450

 gtgtggaaga gttcaagctg aagaagatgt ggaaaagtcc caatggaact 500

 atccggaaca tcctgggggg gactgtcttc cgggagccca tcatctgcaa 550

 aaacatccca cgcctagtcc ctggctggac caagcccatc accattggca 600

 ggcacgccca tggcgaccag tacaaggcca cagactttgt ggcagaccgg 650

 gccggcactt tcaaaatggt cttcacccca aaagatggca gtggtgtcaa 700

 ggagtgggaa gtgtacaact tccccgcagg cggcgtgggc atgggcatgt 750

 acaacaccga cgagtccatc tcaggttttg cgcacagctg cttccagtat 800

 gccatccaga agaaatggcc gctgtacatg agcaccaaga acaccatact 850

 gaaagcctac gatgggcgtt tcaaggacat cttccaggag atctttgaca 900

 agcactataa gaccgacttc gacaagaata agatctggta tgagcaccgg 950

 ctcattgatg acatggtggc tcaggtcctc aagtcttcgg gtggctttgt 1000

 gtgggcctgc aagaactatg acggagatgt gcagtcagac atcctggccc 1050

 agggctttgg ctcccttggc ctgatgacgt ccgtcctggt ctgccctgat 1100

 gggaagacga ttgaggctga ggccgctcat gggaccgtca cccgccacta 1150

 tcgggagcac cagaagggcc ggcccaccag caccaacccc atcgccagca 1200

 tctttgcctg gacacgtggc ctggagcacc gggggaagct ggatgggaac 1250

 caagacctca tcaggtttgc ccagatgctg gagaaggtgt gcgtggagac 1300

 ggtggagagt ggagccatga ccaaggacct ggcgggctgc attcacggcc 1350

 tcagcaatgt gaagctgaac gagcacttcc tgaacaccac ggacttcctc 1400

 gacaccatca agagcaacct ggacagagcc ctgggcaggc agtaggggga 1450

 ggcgccaccc atggctgcag tggaggggcc agggctgagc cggcgggtcc 1500

 tcctgagcgc ggcagagggt gagcctcaca gcccctctct ggaggccttt 1550

 ctaggggatg tttttttata agccagatgt ttttaaaagc atatgtgtgt 1600

 ttcccctcat ggtgacgtga ggcaggagca gtgcgtttta cctcagccag 1650

 tcagtatgtt ttgcatactg taatttatat tgcccttgga acacatggtg 1700

 ccatatttag ctactaaaaa gctcttcaca aaaaaaaaaa 1740

<210> 2163
<211> 452
<212> PRT
<213> Homo sapien

<400> 2163
 Met Ala Gly Tyr Leu Arg Val Val Arg Ser Leu Cys Arg Ala Ser
   1               5                  10                  15

 Gly Ser Arg Pro Ala Trp Ala Pro Ala Ala Leu Thr Ala Pro Thr
                  20                  25                  30

 Ser Gln Glu His Pro Arg Arg His Tyr Ala Asp Lys Arg Ile Lys
                  35                  40                  45

 Val Ala Lys Pro Val Val Glu Met Asp Gly Asp Glu Met Thr Arg
                  50                  55                  60

 Ile Ile Trp Gln Phe Ile Lys Glu Lys Leu Ile Leu Pro His Val
                  65                  70                  75

 Asp Ile Gln Leu Lys Tyr Phe Asp Leu Gly Leu Pro Asn Arg Asp
                  80                  85                  90

 Gln Thr Asp Asp Gln Val Thr Ile Asp Ser Ala Leu Ala Thr Gln
                  95                 100                 105

 Lys Tyr Ser Val Ala Val Lys Cys Ala Thr Ile Thr Pro Asp Glu
                 110                 115                 120

 Ala Arg Val Glu Glu Phe Lys Leu Lys Lys Met Trp Lys Ser Pro
                 125                 130                 135

 Asn Gly Thr Ile Arg Asn Ile Leu Gly Gly Thr Val Phe Arg Glu
                 140                 145                 150

 Pro Ile Ile Cys Lys Asn Ile Pro Arg Leu Val Pro Gly Trp Thr
                 155                 160                 165

 Lys Pro Ile Thr Ile Gly Arg His Ala His Gly Asp Gln Tyr Lys
                 170                 175                 180

 Ala Thr Asp Phe Val Ala Asp Arg Ala Gly Thr Phe Lys Met Val
                 185                 190                 195

 Phe Thr Pro Lys Asp Gly Ser Gly Val Lys Glu Trp Glu Val Tyr
                 200                 205                 210

 Asn Phe Pro Ala Gly Gly Val Gly Met Gly Met Tyr Asn Thr Asp
                 215                 220                 225

 Glu Ser Ile Ser Gly Phe Ala His Ser Cys Phe Gln Tyr Ala Ile
                 230                 235                 240

 Gln Lys Lys Trp Pro Leu Tyr Met Ser Thr Lys Asn Thr Ile Leu
                 245                 250                 255

 Lys Ala Tyr Asp Gly Arg Phe Lys Asp Ile Phe Gln Glu Ile Phe
                 260                 265                 270

 Asp Lys His Tyr Lys Thr Asp Phe Asp Lys Asn Lys Ile Trp Tyr
                 275                 280                 285

 Glu His Arg Leu Ile Asp Asp Met Val Ala Gln Val Leu Lys Ser
                 290                 295                 300

 Ser Gly Gly Phe Val Trp Ala Cys Lys Asn Tyr Asp Gly Asp Val
                 305                 310                 315

 Gln Ser Asp Ile Leu Ala Gln Gly Phe Gly Ser Leu Gly Leu Met
                 320                 325                 330

 Thr Ser Val Leu Val Cys Pro Asp Gly Lys Thr Ile Glu Ala Glu
                 335                 340                 345

 Ala Ala His Gly Thr Val Thr Arg His Tyr Arg Glu His Gln Lys
                 350                 355                 360

 Gly Arg Pro Thr Ser Thr Asn Pro Ile Ala Ser Ile Phe Ala Trp
                 365                 370                 375

 Thr Arg Gly Leu Glu His Arg Gly Lys Leu Asp Gly Asn Gln Asp
                 380                 385                 390

 Leu Ile Arg Phe Ala Gln Met Leu Glu Lys Val Cys Val Glu Thr
                 395                 400                 405

 Val Glu Ser Gly Ala Met Thr Lys Asp Leu Ala Gly Cys Ile His
                 410                 415                 420

 Gly Leu Ser Asn Val Lys Leu Asn Glu His Phe Leu Asn Thr Met
                 425                 430                 435

 Asp Phe Leu Asp Thr Ile Lys Ser Asn Leu Asp Arg Ala Leu Gly
                 440                 445                 450

 Arg Gln


<210> 2164
<211> 3415
<212> DNA
<213> Homo sapien

<400> 2164
 gggagcagct agggcgcggg tctccctcct cccggagttt ggaacggctg 50

 aagttcacct tccagcccct agcgccgttc gcgccgctag gcctggcttc 100

 tgaggcggtt gcggtgctcg gtcgccgcct aggcggggca gggtgcgagc 150

 aggggcttcg ggccacgctt ctcttggcga caggattttg ctgaagtccg 200

 tccgggaaac ggaggaaaaa aagagttgcg ggaggctgtc ggctaataac 250

 ggttcttgat acatatttgc cagacttcaa gatttcagaa aaggggtgaa 300

 agagaagatt gcaactttga gtcagacctg taggcctgat agactgatta 350

 aaccacagaa ggtgacctgc tgagaaaagt ggtacaaata ctgggaaaaa 400

 cctgctcttc tgcgttaagt gggagacaat gtcacaagtt aaaagctctt 450

 attcctatga tgccccctcg gatttcatca atttttcatc cttggatgat 500

 gaaggagata ctcaaaacat agattcatgg tttgaggaga aggccaattt 550

 ggagaataag ttactgggga agaatggaac tggagggctt tttcagggca 600

 aaactccttt gagaaaggct aatcttcagc aagctattgt cacacctttg 650

 aaaccagttg acaacactta ctacaaagag gcagaaaaag aaaatcttgt 700

 ggaacaatcc attccgtcaa atgcttgttc ttccctggaa gttgaggcag 750

 ccatatcaag aaaaactcca gcccagcctc agagaagatc tcttaggctt 800

 tctgctcaga aggatttgga acagaaagaa aagcatcatg taaaaatgaa 850

 agccaagaga tgtgccactc ctgtaatcat cgatgaaatt ctaccctcta 900

 agaaaatgaa agtttctaac aacaaaaaga agccagagga agaaggcagt 950

 gctcatcaag atactgctga aaagaatgca tcttccccag agaaagccaa 1000

 gggtagacat actgtgcctt gtatgccacc tgcaaagcag aagtttctaa 1050

 aaagtactga ggagcaagag ctggagaaga gtatgaaaat gcagcaagag 1100

 gtggtggaga tgcggaaaaa gaatgaagaa ttcaagaaac ttgctctggc 1150

 tggaataggg caacctgtga agaaatcagt gagccaggtc accaaatcag 1200

 ttgacttcca cttccgcaca gatgagcgaa tcaaacaaca tcctaagaac 1250

 caggaggaat ataaggaagt gaactttaca tctgaactac gaaagcatcc 1300

 ttcatctcct gcccgagtga ctaagggatg taccattgtt aagcctttca 1350

 acctgtccca aggaaagaaa agaacatttg atgaaacagt ttctacatat 1400

 gtgccccttg cacagcaagt tgaagacttc cataaacgaa cccctaacag 1450

 atatcatttg aggagcaaga aggatgatat taacctgtta ccctccaaat 1500

 cttctgtgac caagatttgc agagacccac agactcctgt actgcaaacc 1550

 aaacaccgtg cacgggctgt gacctgcaaa agtacagcag agctggaggc 1600

 tgaggagctc gagaaattgc aacaatacaa attcaaagca cgtgaacttg 1650

 atcccagaat acttgaaggt gggcccatct tgcccaagaa accacctgtg 1700

 aaaccaccca ccgagcctat tggctttgat ttggaaattg agaaaagaat 1750

 ccaggagcga gaatcaaaga agaaaacaga ggatgaacac tttgaatttc 1800

 attccagacc ttgccctact aagattttgg aagatgttgt gggtgttcct 1850

 gaaaagaagg tacttccaat caccgtcccc aagtcaccag cctttgcatt 1900

 gaagaacaga attcgaatgc ccaccaaaga agatgaggaa gaggacgaac 1950

 cggtagtgat aaaagctcaa cctgtgccac attatggggt gccttttaag 2000

 ccccaaatcc cagaggcaag aactgtggaa atatgccctt tctcgtttga 2050

 ttctcgagac aaagaacgtc agttacagaa ggagaagaaa ataaaagaac 2100

 tgcagaaagg ggaggtgccc aagttcaagg cacttccctt gcctcatttt 2150

 gacaccatta acctgccaga gaagaaggta aagaatgtga cccagattga 2200

 acctttctgc ttggagactg acagaagagg tgctctgaag gcacagactt 2250

 ggaagcacca gctggaagaa gaactgagac agcagaaaga agcagcttgt 2300

 ttcaaggctc gtccaaacac cgtcatctct caggagccct ttgttcccaa 2350

 gaaagagaag aaatcagttg ctgagggcct ttctggttct ctagttcagg 2400

 aaccttttca gctggctact gagaagagag ccaaagagcg gcaggagctg 2450

 gagaagagaa tggctgaggt agaagcccag aaagcccagc agttggagga 2500

 ggccagacta caggaggaag agcagaaaaa agaggagctg gccaggctac 2550

 ggagagaact ggtgcataag gcaaatccaa tacgcaagta ccagggtctg 2600

 gagataaagt caagtgacca gcctctgact gtgcctgtat ctcccaaatt 2650

 ctccactcga ttccactgct aaactcagct gtgagctgcg gataccgccc 2700

 ggcaatggga cctgctctta acctcaaacc taggaccgtc ttgctttgtc 2750

 attgggcatg gagagaaccc atttctccag acttttacct acccgtgcct 2800

 gagaaagcat acttgacaac tgtggactcc agttttgttg agaattgttt 2850

 tcttacatta ctaaggctaa taatgagatg taactcatga atgtctcgat 2900

 tagactccat gtagttactt cctttaaacc atcagccggc cttttatatg 2950

 ggtcttcact ctgactagaa tttagtctct gtgtcagcac agtgtaatct 3000

 ctattgctat tgccccttac gactctcacc ctctccccac tttttttaaa 3050

 aattttaacc agaaaataaa gatagttaaa tcctaagata gagattaagt 3100

 catggtttaa atgaggaaca atcagtaaat cagattctgt cctcttctct 3150

 gcataccgtg aatttatagt taaggatccc tttgctgtga gggtagaaaa 3200

 cctcaccaac tgcaccagtg aggaagaaga ctgcgtggat tcatggggag 3250

 cctcacagca gccacgcagc aggctctggg tggggctgcc gttaaggcac 3300

 gttctttcct tactggtgct gataacaaca gggaaccgtg cagtgtgcat 3350

 tttaagacct ggcctggaat aaatacgttt tgtctttccc tcaaaaaaaa 3400

 aaaaaaaaaa aaaaa 3415

<210> 2165
<211> 747
<212> PRT
<213> Homo sapien

<400> 2165
 Met Ser Gln Val Lys Ser Ser Tyr Ser Tyr Asp Ala Pro Ser Asp
   1               5                  10                  15

 Phe Ile Asn Phe Ser Ser Leu Asp Asp Glu Gly Asp Thr Gln Asn
                  20                  25                  30

 Ile Asp Ser Trp Phe Glu Glu Lys Ala Asn Leu Glu Asn Lys Leu
                  35                  40                  45

 Leu Gly Lys Asn Gly Thr Gly Gly Leu Phe Gln Gly Lys Thr Pro
                  50                  55                  60

 Leu Arg Lys Ala Asn Leu Gln Gln Ala Ile Val Thr Pro Leu Lys
                  65                  70                  75

 Pro Val Asp Asn Thr Tyr Tyr Lys Glu Ala Glu Lys Glu Asn Leu
                  80                  85                  90

 Val Glu Gln Ser Ile Pro Ser Asn Ala Cys Ser Ser Leu Glu Val
                  95                 100                 105

 Glu Ala Ala Ile Ser Arg Lys Thr Pro Ala Gln Pro Gln Arg Arg
                 110                 115                 120

 Ser Leu Arg Leu Ser Ala Gln Lys Asp Leu Glu Gln Lys Glu Lys
                 125                 130                 135

 His His Val Lys Met Lys Ala Lys Arg Cys Ala Thr Pro Val Ile
                 140                 145                 150

 Ile Asp Glu Ile Leu Pro Ser Lys Lys Met Lys Val Ser Asn Asn
                 155                 160                 165

 Lys Lys Lys Pro Glu Glu Glu Gly Ser Ala His Gln Asp Thr Ala
                 170                 175                 180

 Glu Lys Asn Ala Ser Ser Pro Glu Lys Ala Lys Gly Arg His Thr
                 185                 190                 195

 Val Pro Cys Met Pro Pro Ala Lys Gln Lys Phe Leu Lys Ser Thr
                 200                 205                 210

 Glu Glu Gln Glu Leu Glu Lys Ser Met Lys Met Gln Gln Glu Val
                 215                 220                 225

 Val Glu Met Arg Lys Lys Asn Glu Glu Phe Lys Lys Leu Ala Leu
                 230                 235                 240

 Ala Gly Ile Gly Gln Pro Val Lys Lys Ser Val Ser Gln Val Thr
                 245                 250                 255

 Lys Ser Val Asp Phe His Phe Arg Thr Asp Glu Arg Ile Lys Gln
                 260                 265                 270

 His Pro Lys Asn Gln Glu Glu Tyr Lys Glu Val Asn Phe Thr Ser
                 275                 280                 285

 Glu Leu Arg Lys His Pro Ser Ser Pro Ala Arg Val Thr Lys Gly
                 290                 295                 300

 Cys Thr Ile Val Lys Pro Phe Asn Leu Ser Gln Gly Lys Lys Arg
                 305                 310                 315

 Thr Phe Asp Glu Thr Val Ser Thr Tyr Val Pro Leu Ala Gln Gln
                 320                 325                 330

 Val Glu Asp Phe His Lys Arg Thr Pro Asn Arg Tyr His Leu Arg
                 335                 340                 345

 Ser Lys Lys Asp Asp Ile Asn Leu Leu Pro Ser Lys Ser Ser Val
                 350                 355                 360

 Thr Lys Ile Cys Arg Asp Pro Gln Thr Pro Val Leu Gln Thr Lys
                 365                 370                 375

 His Arg Ala Arg Ala Val Thr Cys Lys Ser Thr Ala Glu Leu Glu
                 380                 385                 390

 Ala Glu Glu Leu Glu Lys Leu Gln Gln Tyr Lys Phe Lys Ala Arg
                 395                 400                 405

 Glu Leu Asp Pro Arg Ile Leu Glu Gly Gly Pro Ile Leu Pro Lys
                 410                 415                 420

 Lys Pro Pro Val Lys Pro Pro Thr Glu Pro Ile Gly Phe Asp Leu
                 425                 430                 435

 Glu Ile Glu Lys Arg Ile Gln Glu Arg Glu Ser Lys Lys Lys Thr
                 440                 445                 450

 Glu Asp Glu His Phe Glu Phe His Ser Arg Pro Cys Pro Thr Lys
                 455                 460                 465

 Ile Leu Glu Asp Val Val Gly Val Pro Glu Lys Lys Val Leu Pro
                 470                 475                 480

 Ile Thr Val Pro Lys Ser Pro Ala Phe Ala Leu Lys Asn Arg Ile
                 485                 490                 495

 Arg Met Pro Thr Lys Glu Asp Glu Glu Glu Asp Glu Pro Val Val
                 500                 505                 510

 Ile Lys Ala Gln Pro Val Pro His Tyr Gly Val Pro Phe Lys Pro
                 515                 520                 525

 Gln Ile Pro Glu Ala Arg Thr Val Glu Ile Cys Pro Phe Ser Phe
                 530                 535                 540

 Asp Ser Arg Asp Lys Glu Arg Gln Leu Gln Lys Glu Lys Lys Ile
                 545                 550                 555

 Lys Glu Leu Gln Lys Gly Glu Val Pro Lys Phe Lys Ala Leu Pro
                 560                 565                 570

 Leu Pro His Phe Asp Thr Ile Asn Leu Pro Glu Lys Lys Val Lys
                 575                 580                 585

 Asn Val Thr Gln Ile Glu Pro Phe Cys Leu Glu Thr Asp Arg Arg
                 590                 595                 600

 Gly Ala Leu Lys Ala Gln Thr Trp Lys His Gln Leu Glu Glu Glu
                 605                 610                 615

 Leu Arg Gln Gln Lys Glu Ala Ala Cys Phe Lys Ala Arg Pro Asn
                 620                 625                 630

 Thr Val Ile Ser Gln Glu Pro Phe Val Pro Lys Lys Glu Lys Lys
                 635                 640                 645

 Ser Val Ala Glu Gly Leu Ser Gly Ser Leu Val Gln Glu Pro Phe
                 650                 655                 660

 Gln Leu Ala Thr Glu Lys Arg Ala Lys Glu Arg Gln Glu Leu Glu
                 665                 670                 675

 Lys Arg Met Ala Glu Val Glu Ala Gln Lys Ala Gln Gln Leu Glu
                 680                 685                 690

 Glu Ala Arg Leu Gln Glu Glu Glu Gln Lys Lys Glu Glu Leu Ala
                 695                 700                 705

 Arg Leu Arg Arg Glu Leu Val His Lys Ala Asn Pro Ile Arg Lys
                 710                 715                 720

 Tyr Gln Gly Leu Glu Ile Lys Ser Ser Asp Gln Pro Leu Thr Val
                 725                 730                 735

 Pro Val Ser Pro Lys Phe Ser Thr Arg Phe His Cys
                 740                 745

<210> 2166
<211> 1888
<212> DNA
<213> Homo sapien

<400> 2166
 gcggcgcggg gcgggcgcag cgggggtcgg ggcgctggga gcccgttggg 50

 ccgcgaacgc agccgccacg ccggggccgc cgagatcggg tgcccgggat 100

 gagcctcatc cggaaaaagg gcttctacaa gcaggacgtc aacaagaccg 150

 cctgggagct gcccaagacc tacgtgtccc cgacgcacgt cggcagcggg 200

 gcctatggct ccgtgtgctc ggccatcgac aagcggtcag gggagaaggt 250

 ggccatcaag aagctgagcc gaccctttca gtccgagatc ttcgccaagc 300

 gcgcctaccg ggagctgctg ctgctgaagc acatgcagca tgagaacgtc 350

 attgggctcc tggatgtctt caccccagcc tcctccctgc gcaacttcta 400

 tgacttctac ctggtgatgc ccttcatgca gacggatctg cagaagatca 450

 tggggatgga gttcagtgag gagaagatcc agtacctggt gtatcagatg 500

 ctcaaaggcc ttaagtacat ccactctgct ggggtcgtgc acagggacct 550

 gaagccaggc aacctggctg tgaatgagga ctgtgaactg aagattctgg 600

 attttgggct ggcgcgacat gcagacgccg agatgactgg ctacgtggtg 650

 acccgctggt accgagcccc cgaggtgatc ctcagctgga tgcactacaa 700

 ccagacagtg gacatctggt ctgtgggctg tatcatggca gagatgctga 750

 cagggaaaac tctgttcaag gggaaagatt acctggacca gctgacccag 800

 atcctgaaag tgaccggggt gcctggcacg gagtttgtgc agaagctgaa 850

 cgacaaagcg gccaaatcct acatccagtc cctgccacag acccccagga 900

 aggatttcac tcagctgttc ccacgggcca gcccccaggc tgcggacctg 950

 ctggagaaga tgctggagct agacgtggac aagcgcctga cggccgcgca 1000

 ggccctcacc catcccttct ttgaaccctt ccgggaccct gaggaagaga 1050

 cggaggccca gcagccgttt gatgattcct tagaacacga gaaactcaca 1100

 gtggatgaat ggaagcagca catctacaag gagattgtga acttcagccc 1150

 cattgcccgg aaggactcac ggcgccggag tggcatgaag ctgtagggac 1200

 tcatcttgca tggcaccacc ggccagacac tgcccaagga ccagtatttg 1250

 tcactaccaa actcagccct tcttggaata cagcctttca agcagaggac 1300

 agaagggtcc ttctccttat gtgggaaatg ggcctagtag atgcagaatt 1350

 caaagatgtc ggttgggaga aactagctct gatcctaaca ggccacgtta 1400

 aactgcccat ctggagaatc gcctgcaggt ggggcccttt ccttcccgcc 1450

 agagtggggc tgagtgggcg ctgagccagg ccgggggcct atggcagtga 1500

 tgctgtgttg gtttcctagg gatgctctaa cgaattacca caaacctggt 1550

 ggattgaaac agcagaactt gattccctta cagttctgga ggctggaaat 1600

 ctgggatgga ggtgttggca gggctgtggt ccctttgaag gctctgggga 1650

 agaatccttc cttggctctt tttagcttgt ggcggcagtg ggcagtccgt 1700

 ggcattcccc agcttattgc tgcatcactc cagtctctgt ctcttctgtt 1750

 ctctcctctt ttaacaacag tcattggatt tagggcccac cctaatcctg 1800

 tgtgatctta tcttgatcct tattaattaa acctgcaaat actctagttc 1850

 caaataaagt cacattctca ggttccaggt ggacatga 1888

<210> 2167
<211> 365
<212> PRT
<213> Homo sapien

<400> 2167
 Met Ser Leu Ile Arg Lys Lys Gly Phe Tyr Lys Gln Asp Val Asn
   1               5                  10                  15

 Lys Thr Ala Trp Glu Leu Pro Lys Thr Tyr Val Ser Pro Thr His
                  20                  25                  30

 Val Gly Ser Gly Ala Tyr Gly Ser Val Cys Ser Ala Ile Asp Lys
                  35                  40                  45

 Arg Ser Gly Glu Lys Val Ala Ile Lys Lys Leu Ser Arg Pro Phe
                  50                  55                  60

 Gln Ser Glu Ile Phe Ala Lys Arg Ala Tyr Arg Glu Leu Leu Leu
                  65                  70                  75

 Leu Lys His Met Gln His Glu Asn Val Ile Gly Leu Leu Asp Val
                  80                  85                  90

 Phe Thr Pro Ala Ser Ser Leu Arg Asn Phe Tyr Asp Phe Tyr Leu
                  95                 100                 105

 Val Met Pro Phe Met Gln Thr Asp Leu Gln Lys Ile Met Gly Met
                 110                 115                 120

 Glu Phe Ser Glu Glu Lys Ile Gln Tyr Leu Val Tyr Gln Met Leu
                 125                 130                 135

 Lys Gly Leu Lys Tyr Ile His Ser Ala Gly Val Val His Arg Asp
                 140                 145                 150

 Leu Lys Pro Gly Asn Leu Ala Val Asn Glu Asp Cys Glu Leu Lys
                 155                 160                 165

 Ile Leu Asp Phe Gly Leu Ala Arg His Ala Asp Ala Glu Met Thr
                 170                 175                 180

 Gly Tyr Val Val Thr Arg Trp Tyr Arg Ala Pro Glu Val Ile Leu
                 185                 190                 195

 Ser Trp Met His Tyr Asn Gln Thr Val Asp Ile Trp Ser Val Gly
                 200                 205                 210

 Cys Ile Met Ala Glu Met Leu Thr Gly Lys Thr Leu Phe Lys Gly
                 215                 220                 225

 Lys Asp Tyr Leu Asp Gln Leu Thr Gln Ile Leu Lys Val Thr Gly
                 230                 235                 240

 Val Pro Gly Thr Glu Phe Val Gln Lys Leu Asn Asp Lys Ala Ala
                 245                 250                 255

 Lys Ser Tyr Ile Gln Ser Leu Pro Gln Thr Pro Arg Lys Asp Phe
                 260                 265                 270

 Thr Gln Leu Phe Pro Arg Ala Ser Pro Gln Ala Ala Asp Leu Leu
                 275                 280                 285

 Glu Lys Met Leu Glu Leu Asp Val Asp Lys Arg Leu Thr Ala Ala
                 290                 295                 300

 Gln Ala Leu Thr His Pro Phe Phe Glu Pro Phe Arg Asp Pro Glu
                 305                 310                 315

 Glu Glu Thr Glu Ala Gln Gln Pro Phe Asp Asp Ser Leu Glu His
                 320                 325                 330

 Glu Lys Leu Thr Val Asp Glu Trp Lys Gln His Ile Tyr Lys Glu
                 335                 340                 345

 Ile Val Asn Phe Ser Pro Ile Ala Arg Lys Asp Ser Arg Arg Arg
                 350                 355                 360

 Ser Gly Met Lys Leu
                 365

<210> 2168
<211> 1614
<212> DNA
<213> Homo sapien

<400> 2168
 gcggccgccc ggcccggccg cggatcagag actggagact gggtcttgct 50

 ctgttaccca ggctggagtg cagtggtgtg atcatagctc actacagcct 100

 tgaactcctg ggctcaagag gttgaggctc cctcctcagc ctcccaagta 150

 gctgggacta caggctttca gcaccatgcc tggctaattc aaaaaaacct 200

 tcagagagat agggtctctc tatgttgccc tagctcgtct caaactcctg 250

 gcctcaagtg atcctcctgc ttggacctcc caaagcgctg ggattacagg 300

 ctcctggaac catgggcctc aggccctgag gatacggggc tcccggtggc 350

 catgacgacg ggtgactgct gccacctccc cggctccctg tgtgactgct 400

 ccggcagccc tgccttctcc aaggtcgtgg aggctacggg cctcggaccg 450

 ccccagtatg tggcacaggt gacttcaagg gatggccggc tcctctccac 500

 cgtcatccgt gccttggaca caccgagtga tggtcctttc tgccggatct 550

 gccatgaggg agcgaacggg gagtgcttgc tgtccccgtg tggctgcacc 600

 ggcacgctgg gtgccgtgca taagagctgt ctggagaagt ggctttcctc 650

 atctaacacc agctactgcg agctgtgcca cacggagttt gcagtggaga 700

 aacggcctcg acccctcaca gagtggctga aggacccggg gccgcggacg 750

 gagaagcgga cactgtgctg cgacatggtg tgtttcctgt tcatcacacc 800

 gctggccgcc atctcaggct ggttgtgcct gcgcggggcc caggaccacc 850

 tccggctcca cagccagctg gaggccgtgg gtctcattgc cctcaccatc 900

 gccctcttca ccatctatgt cctctggacg ctggtctcct tccgctacca 950

 ctgccagctg tactccgagt ggagaaagac caaccagaaa gttcgcctga 1000

 agatccggga ggcggacagc cccgagggcc cccagcattc tccactggca 1050

 gctggactcc tgaagaaggt ggcagaggag acaccagtat gaatgctggg 1100

 ctctccggac cctgcagcag agaggccaga ggtagctggt gataccctgt 1150

 cctgtggaag gacttccact tcaacacttc cacttcaaca gttcccgcac 1200

 ggcctgaacg cttcttaggc caagagacac catgcggagc ctagtctgtg 1250

 atcctgtgtg aagatatttt cagggttttt tttttttttt ttttgcatat 1300

 ggaggacagg tggacatggt cctgagctct ggacggagca ggcaccctga 1350

 tctcattctg aggtccacat ggcaccttct gggccagcag ctgtggccgg 1400

 tgtatcaagg gcgcccttaa agctggaaca ttccagcaag cttcttgcgc 1450

 ttctctgcac ccggcaggcc cactttcctg gcaccctcga ctttatataa 1500

 aagttgcact gcgtttcaaa aacccaccct gaatgaataa aaggagccct 1550

 ggctggacgt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1600

 aaaaaaaaaa aaaa 1614

<210> 2169
<211> 246
<212> PRT
<213> Homo sapien

<400> 2169
 Met Thr Thr Gly Asp Cys Cys His Leu Pro Gly Ser Leu Cys Asp
   1               5                  10                  15

 Cys Ser Gly Ser Pro Ala Phe Ser Lys Val Val Glu Ala Thr Gly
                  20                  25                  30

 Leu Gly Pro Pro Gln Tyr Val Ala Gln Val Thr Ser Arg Asp Gly
                  35                  40                  45

 Arg Leu Leu Ser Thr Val Ile Arg Ala Leu Asp Thr Pro Ser Asp
                  50                  55                  60

 Gly Pro Phe Cys Arg Ile Cys His Glu Gly Ala Asn Gly Glu Cys
                  65                  70                  75

 Leu Leu Ser Pro Cys Gly Cys Thr Gly Thr Leu Gly Ala Val His
                  80                  85                  90

 Lys Ser Cys Leu Glu Lys Trp Leu Ser Ser Ser Asn Thr Ser Tyr
                  95                 100                 105

 Cys Glu Leu Cys His Thr Glu Phe Ala Val Glu Lys Arg Pro Arg
                 110                 115                 120

 Pro Leu Thr Glu Trp Leu Lys Asp Pro Gly Pro Arg Thr Glu Lys
                 125                 130                 135

 Arg Thr Leu Cys Cys Asp Met Val Cys Phe Leu Phe Ile Thr Pro
                 140                 145                 150

 Leu Ala Ala Ile Ser Gly Trp Leu Cys Leu Arg Gly Ala Gln Asp
                 155                 160                 165

 His Leu Arg Leu His Ser Gln Leu Glu Ala Val Gly Leu Ile Ala
                 170                 175                 180

 Leu Thr Ile Ala Leu Phe Thr Ile Tyr Val Leu Trp Thr Leu Val
                 185                 190                 195

 Ser Phe Arg Tyr His Cys Gln Leu Tyr Ser Glu Trp Arg Lys Thr
                 200                 205                 210

 Asn Gln Lys Val Arg Leu Lys Ile Arg Glu Ala Asp Ser Pro Glu
                 215                 220                 225

 Gly Pro Gln His Ser Pro Leu Ala Ala Gly Leu Leu Lys Lys Val
                 230                 235                 240

 Ala Glu Glu Thr Pro Val
                 245

<210> 2170
<211> 2650
<212> DNA
<213> Homo sapien

<400> 2170
 gccgcgctgg tggcggcggc gcgtcgttgc agttgcgcca tctgtcagga 50

 gcggagccgg cgaggagggg gctgccgcgg gcgaggagga ggggtcgccg 100

 cgagccgaag gccttcgaga cccgcccgcc gcccggcggc gagagtagag 150

 gcgaggttgt tgtgcgagcg gcgcgtcctc tcccgcccgg gcgcgccgcg 200

 cttctcccag cgcaccgagg accgcccggg cgcacacaaa gccgccgccc 250

 gcgccgcacc gcccggcggc cgccgcccgc gccagggagg gattcggccg 300

 ccgggccggg gacaccccgg cgccgccccc tcggtgctct cggaaggccc 350

 accggctccc gggcccgccg gggacccccc ggagccgcct cggccgcgcc 400

 ggaggagggc ggggagagga ccatgtgagt gggctccgga gcctcagcgc 450

 cgcgcagttt ttttgaagaa gcaggatgct gatctaaacg tggaaaaaga 500

 ccagtcctgc ctctgttgta gaagacatgt ggtgtatata aagtttgtga 550

 tcgttggcgg acattttgga atttagataa tgggctgtgt gcaatgtaag 600

 gataaagaag caacaaaact gacggaggag agggacggca gcctgaacca 650

 gagctctggg taccgctatg gcacagaccc cacccctcag cactacccca 700

 gcttcggtgt gacctccatc cccaactaca acaacttcca cgcagccggg 750

 ggccaaggac tcaccgtctt tggaggtgtg aactcttcgt ctcatacggg 800

 gaccttgcgt acgagaggag gaacaggagt gacactcttt gtggcccttt 850

 atgactatga agcacggaca gaagatgacc tgagttttca caaaggagaa 900

 aaatttcaaa tattgaacag ctcggaagga gattggtggg aagcccgctc 950

 cttgacaact ggagagacag gttacattcc cagcaattat gtggctccag 1000

 ttgactctat ccaggcagaa gagtggtact ttggaaaact tggccgaaaa 1050

 gatgctgagc gacagctatt gtcctttgga aacccaagag gtacctttct 1100

 tatccgcgag agtgaaacca ccaaaggtgc ctattcactt tctatccgtg 1150

 attgggatga tatgaaagga gaccatgtca aacattataa aattcgcaaa 1200

 cttgacaatg gtggatacta cattaccacc cgggcccagt ttgaaacact 1250

 tcagcagctt gtacaacatt actcagagag agctgcaggt ctctgctgcc 1300

 gcctagtagt tccctgtcac aaagggatgc caaggcttac cgatctgtct 1350

 gtcaaaacca aagatgtctg ggaaatccct cgagaatccc tgcagttgat 1400

 caagagactg ggaaatgggc agtttgggga agtatggatg ggtacctgga 1450

 atggaaacac aaaagtagcc ataaagactc ttaaaccagg cacaatgtcc 1500

 cccgaatcat tccttgagga agcgcagatc atgaagaagc tgaagcacga 1550

 caagctggtc cagctctatg cagtggtgtc tgaggagccc atctacatcg 1600

 tcaccgagta tatgaacaaa ggaagtttac tggatttctt aaaagatgga 1650

 gaaggaagag ctctgaaatt accaaatctt gtggacatgg cagcacaggt 1700

 ggctgcagga atggcttaca tcgagcgcat gaattatatc catagagatc 1750

 tgcgatcagc aaacattcta gtggggaatg gactcatatg caagattgct 1800

 gacttcggat tggcccgatt gatagaagac aatgagtaca cagcaagaca 1850

 aggtgcaaag ttccccatca agtggacggc ccccgaggca gccctgtacg 1900

 ggaggttcac aatcaagtct gacgtgtggt cttttggaat cttactcaca 1950

 gagctggtca ccaaaggaag agtgccatac ccaggcatga acaaccggga 2000

 ggtgctggag caggtggagc gaggctacag gatgccctgc ccgcaggact 2050

 gccccatctc tctgcatgag ctcatgatcc actgctggaa aaaggaccct 2100

 gaagaacgcc ccacttttga gtacttgcag agcttcctgg aagactactt 2150

 taccgcgaca gagccccagt accaacctgg tgaaaacctg taaggcccgg 2200

 gtctgcggag agaggccttg tcccagaggc tgccccaccc ctccccatta 2250

 gctttcaatt ccgtagccag ctgctcccca gcagcggaac cgcccaggat 2300

 cagattgcat gtgactctga agctgacgaa cttccatggc cctcattaat 2350

 gacacttgtc cccaaatccg aacctcctct gtgaagcatt cgagacagaa 2400

 ccttgttatt tctcagactt tggaaaatgc attgtatcga tgttatgtaa 2450

 aaggccaaac ctctgttcag tgtaaatagt tactccagtg ccaacaatcc 2500

 tagtgctttc cttttttaaa aatgcaaatc ctatgtgatt ttaactctgt 2550

 cttcacctga ttcaactaaa aaaaaaaaag tattattttc caaaagtggc 2600

 ctctttgtct aaaacaataa aatttttttt catgttttaa caaaaaccaa 2650

<210> 2171
<211> 537
<212> PRT
<213> Homo sapien

<400> 2171
 Met Gly Cys Val Gln Cys Lys Asp Lys Glu Ala Thr Lys Leu Thr
   1               5                  10                  15

 Glu Glu Arg Asp Gly Ser Leu Asn Gln Ser Ser Gly Tyr Arg Tyr
                  20                  25                  30

 Gly Thr Asp Pro Thr Pro Gln His Tyr Pro Ser Phe Gly Val Thr
                  35                  40                  45

 Ser Ile Pro Asn Tyr Asn Asn Phe His Ala Ala Gly Gly Gln Gly
                  50                  55                  60

 Leu Thr Val Phe Gly Gly Val Asn Ser Ser Ser His Thr Gly Thr
                  65                  70                  75

 Leu Arg Thr Arg Gly Gly Thr Gly Val Thr Leu Phe Val Ala Leu
                  80                  85                  90

 Tyr Asp Tyr Glu Ala Arg Thr Glu Asp Asp Leu Ser Phe His Lys
                  95                 100                 105

 Gly Glu Lys Phe Gln Ile Leu Asn Ser Ser Glu Gly Asp Trp Trp
                 110                 115                 120

 Glu Ala Arg Ser Leu Thr Thr Gly Glu Thr Gly Tyr Ile Pro Ser
                 125                 130                 135

 Asn Tyr Val Ala Pro Val Asp Ser Ile Gln Ala Glu Glu Trp Tyr
                 140                 145                 150

 Phe Gly Lys Leu Gly Arg Lys Asp Ala Glu Arg Gln Leu Leu Ser
                 155                 160                 165

 Phe Gly Asn Pro Arg Gly Thr Phe Leu Ile Arg Glu Ser Glu Thr
                 170                 175                 180

 Thr Lys Gly Ala Tyr Ser Leu Ser Ile Arg Asp Trp Asp Asp Met
                 185                 190                 195

 Lys Gly Asp His Val Lys His Tyr Lys Ile Arg Lys Leu Asp Asn
                 200                 205                 210

 Gly Gly Tyr Tyr Ile Thr Thr Arg Ala Gln Phe Glu Thr Leu Gln
                 215                 220                 225

 Gln Leu Val Gln His Tyr Ser Glu Arg Ala Ala Gly Leu Cys Cys
                 230                 235                 240

 Arg Leu Val Val Pro Cys His Lys Gly Met Pro Arg Leu Thr Asp
                 245                 250                 255

 Leu Ser Val Lys Thr Lys Asp Val Trp Glu Ile Pro Arg Glu Ser
                 260                 265                 270

 Leu Gln Leu Ile Lys Arg Leu Gly Asn Gly Gln Phe Gly Glu Val
                 275                 280                 285

 Trp Met Gly Thr Trp Asn Gly Asn Thr Lys Val Ala Ile Lys Thr
                 290                 295                 300

 Leu Lys Pro Gly Thr Met Ser Pro Glu Ser Phe Leu Glu Glu Ala
                 305                 310                 315

 Gln Ile Met Lys Lys Leu Lys His Asp Lys Leu Val Gln Leu Tyr
                 320                 325                 330

 Ala Val Val Ser Glu Glu Pro Ile Tyr Ile Val Thr Glu Tyr Met
                 335                 340                 345

 Asn Lys Gly Ser Leu Leu Asp Phe Leu Lys Asp Gly Glu Gly Arg
                 350                 355                 360

 Ala Leu Lys Leu Pro Asn Leu Val Asp Met Ala Ala Gln Val Ala
                 365                 370                 375

 Ala Gly Met Ala Tyr Ile Glu Arg Met Asn Tyr Ile His Arg Asp
                 380                 385                 390

 Leu Arg Ser Ala Asn Ile Leu Val Gly Asn Gly Leu Ile Cys Lys
                 395                 400                 405

 Ile Ala Asp Phe Gly Leu Ala Arg Leu Ile Glu Asp Asn Glu Tyr
                 410                 415                 420

 Thr Ala Arg Gln Gly Ala Lys Phe Pro Ile Lys Trp Thr Ala Pro
                 425                 430                 435

 Glu Ala Ala Leu Tyr Gly Arg Phe Thr Ile Lys Ser Asp Val Trp
                 440                 445                 450

 Ser Phe Gly Ile Leu Leu Thr Glu Leu Val Thr Lys Gly Arg Val
                 455                 460                 465

 Pro Tyr Pro Gly Met Asn Asn Arg Glu Val Leu Glu Gln Val Glu
                 470                 475                 480

 Arg Gly Tyr Arg Met Pro Cys Pro Gln Asp Cys Pro Ile Ser Leu
                 485                 490                 495

 His Glu Leu Met Ile His Cys Trp Lys Lys Asp Pro Glu Glu Arg
                 500                 505                 510

 Pro Thr Phe Glu Tyr Leu Gln Ser Phe Leu Glu Asp Tyr Phe Thr
                 515                 520                 525

 Ala Thr Glu Pro Gln Tyr Gln Pro Gly Glu Asn Leu
                 530                 535

<210> 2172
<211> 7905
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2521-2545
<223> Unknown base

<400> 2172
 aaaaaatgca gcatcaacgg cagcagcaag cggaccacgc gaacgaggca 50

 aactatgcaa gaggcaccag acttcctctt tctggtgaag gaccaacttc 100

 tcagccgaat agctccaagc aaactgtcct gtcttggcaa gctgcaatcg 150

 atgctgctag acaggccaag gctgcccaaa ctatgagcac ctctgcaccc 200

 ccacctgtag gatctctctc ccaaagaaaa cgtcagcaat acgccaagag 250

 caaaaaacag ggtaactcgt ccaacagccg acctgcccgc gcccttttct 300

 gtttatcact caataacccc atccgaagag cctgcattag tatagtggaa 350

 tggaaaccat ttgacatatt tatattattg gctatttttg ccaattgtgt 400

 ggccttagct atttacatcc cattccctga agatgattct aattcaacaa 450

 atcataactt ggaaaaagta gaatatgcct tcctgattat ttttacagtc 500

 gagacatttt tgaagattat agcgtatgga ttattgctac atcctaatgc 550

 ttatgttagg aatggatgga atttactgga ttttgttata gtaatagtag 600

 gattgtttag tgtaattttg gaacaattaa ccaaagaaac agaaggcggg 650

 aaccactcaa gcggcaaatc tggaggcttt gatgtcaaag ccctccgtgc 700

 ctttcgagtg ttgcgaccac ttcgactagt gtcaggagtg cccagtttac 750

 aagttgtcct gaactccatt ataaaagcca tggttcccct ccttcacata 800

 gcccttttgg tattatttgt aatcataatc tatgctatta taggattgga 850

 actttttatt ggaaaaatgc acaaaacatg tttttttgct gactcagata 900

 tcgtagctga agaggaccca gctccatgtg cgttctcagg gaatggacgc 950

 cagtgtactg ccaatggcac ggaatgtagg agtggctggg ttggcccgaa 1000

 cggaggcatc accaactttg ataactttgc ctttgccatg cttactgtgt 1050

 ttcagtgcat caccatggag ggctggacag acgtgctcta ctgggtaaat 1100

 gatgcgatag gatgggaatg gccatgggtg tattttgtta gtctgatcat 1150

 ccttggctca tttttcgtcc ttaacctggt tcttggtgtc cttagtggag 1200

 aattctcaaa ggaaagagag aaggcaaaag cacggggaga tttccagaag 1250

 ctccgggaga agcagcagct ggaggaggat ctaaagggct acttggattg 1300

 gatcacccaa gctgaggaca tcgatccgga gaatgaggaa gaaggaggag 1350

 aggaaggcaa acgaaatact agcatgccca ccagcgagac tgagtctgtg 1400

 aacacagaga acgtcagcgg tgaaggcgag aaccgaggct gctgtggaag 1450

 tctctggtgc tggtggagac ggagaggcgc ggccaaggcg gggccctctg 1500

 ggtgtcggcg gtggggtcaa gccatctcaa aatccaaact cagccgacgc 1550

 tggcgtcgct ggaaccgatt caatcgcaga agatgtaggg ccgccgtgaa 1600

 gtctgtcacg ttttactggc tggttatcgt cctggtgttt ctgaacacct 1650

 taaccatttc ctctgagcac tacaatcagc cagattggtt gacacagatt 1700

 caagatattg ccaacaaagt cctcttggct ctgttcacct gcgagatgct 1750

 ggtaaaaatg tacagcttgg gcctccaagc atatttcgtc tctcttttca 1800

 accggtttga ttgcttcgtg gtgtgtggtg gaatcactga gacgatcctg 1850

 gtggaactgg aaatcatgtc tcccctgggg atctctgtgt ttcggtgtgt 1900

 gcgcctctta agaatcttca aagtgaccag gcactggact tccctgagca 1950

 acttagtggc atccttatta aactccatga agtccatcgc ttcgctgttg 2000

 cttctgcttt ttctcttcat tatcatcttt tccttgcttg ggatgcagct 2050

 gtttggcggc aagtttaatt ttgatgaaac gcaaaccaag cggagcacct 2100

 ttgacaattt ccctcaagca cttctcacag tgttccagat cctgacaggc 2150

 gaagactgga atgctgtgat gtacgatggc atcatggctt acgggggccc 2200

 atcctcttca ggaatgatcg tctgcatcta cttcatcatc ctcttcattt 2250

 gtggtaacta tattctactg aatgtcttct tggccatcgc tgtagacaat 2300

 ttggctgatg ctgaaagtct gaacactgct cagaaagaag aagcggaaga 2350

 aaaggagagg aaaaagattg ccagaaaaga gagcctagaa aataaaaaga 2400

 acaacaaacc agaagtcaac cagatagcca acagtgacaa caaggttaca 2450

 attgatgact atagagaaga ggatgaagac aaggacccct atccgccttg 2500

 cgatgtgcca gtaggggaag nnnnnnnnnn nnnnnnnnnn nnnnnacctg 2550

 aggttcctgc cggaccccgt cctcgaagga tctcggagtt gaacatgaag 2600

 gaaaaaattg cccccatccc tgaagggagc gctttcttca ttcttagcaa 2650

 gaccaacccg atccgcgtag gctgccacaa gctcatcaac caccacatct 2700

 tcaccaacct catccttgtc ttcatcatgc tgagcagcgc tgccctggcc 2750

 gcagaggacc ccatccgcag ccactccttc cggaacacga tactgggtta 2800

 ctttgactat gccttcacag ccatctttac tgttgagatc ctgttgaaga 2850

 tgacaacttt tggagctttc ctccacaaag gggccttctg caggaactac 2900

 ttcaatttgc tggatatgct ggtggttggg gtgtctctgg tgtcatttgg 2950

 gattcaatcc agtgccatct ccgttgtgaa gattctgagg gtcttaaggg 3000

 tcctgcgtcc cctcagggcc atcaacagag caaaaggact taagcacgtg 3050

 gtccagtgcg tcttcgtggc catccggacc atcggcaaca tcatgatcgt 3100

 cactaccctc ctgcagttca tgtttgcctg tatcggggtc cagttgttca 3150

 aggggaagtt ctatcgctgt acggatgaag ccaaaagtaa ccctgaagaa 3200

 tgcaggggac ttttcatcct ctacaaggat ggggatgttg acagtcctgt 3250

 ggtccgtgaa cggatctggc aaaacagtga tttcaacttc gacaacgtcc 3300

 tctctgctat gatggcgctc ttcacagtct ccacgtttga gggctggcct 3350

 gcgttgctgt ataaagccat cgactcgaat ggagagaaca tcggcccaat 3400

 ctacaaccac cgcgtggaga tctccatctt cttcatcatc tacatcatca 3450

 ttgtagcttt cttcatgatg aacatctttg tgggctttgt catcgttaca 3500

 tttcaggaac aaggagaaaa agagtataag aactgtgagc tggacaaaaa 3550

 tcagcgtcag tgtgttgaat acgccttgaa agcacgtccc ttgcggagat 3600

 acatccccaa aaacccctac cagtacaagt tctggtacgt ggtgaactct 3650

 tcgcctttcg aatacatgat gtttgtcctc atcatgctca acacactctg 3700

 cttggccatg cagcactacg agcagtccaa gatgttcaat gatgccatgg 3750

 acattctgaa catggtcttc accggggtgt tcaccgtcga gatggttttg 3800

 aaagtcatcg catttaagcc taaggggtat tttagtgacg cctggaacac 3850

 gtttgactcc ctcatcgtaa tcggcagcat tatagacgtg gccctcagcg 3900

 aagcggaccc aactgaaagt gaaaatgtcc ctgtcccaac tgctacacct 3950

 gggaactctg aagagagcaa tagaatctcc atcacctttt tccgtctttt 4000

 ccgagtgatg cgattggtga agcttctcag caggggggaa ggcatccgga 4050

 cattgctgtg gacttttatt aagtcctttc aggcgctccc gtatgtggcc 4100

 ctcctcatag ccatgctgtt cttcatctat gcggtcattg gcatgcagat 4150

 gtttgggaaa gttgccatga gagataacaa ccagatcaat aggaacaata 4200

 acttccagac gtttccccag gcggtgctgc tgctcttcag gtgtgcaaca 4250

 ggtgaggcct ggcaggagat catgctggcc tgtctcccag ggaagctctg 4300

 tgaccctgag tcagattaca accccgggga ggagtataca tgtgggagca 4350

 actttgccat tgtctatttc atcagttttt acatgctctg tgcatttctg 4400

 atcatcaatc tgtttgtggc tgtcatcatg gataatttcg actatctgac 4450

 ccgggactgg tctattttgg ggcctcacca tttagatgaa ttcaaaagaa 4500

 tatggtcaga atatgaccct gaggcaaagg gaaggataaa acaccttgat 4550

 gtggtcactc tgcttcgacg catccagcct cccctggggt ttgggaagtt 4600

 atgtccacac agggtagcgt gcaagagatt agttgccatg aacatgcctc 4650

 tcaacagtga cgggacagtc atgtttaatg caaccctgtt tgctttggtt 4700

 cgaacggctc ttaagatcaa gaccgaaggg aacctggagc aagctaatga 4750

 agaacttcgg gctgtgataa agaaaatttg gaagaaaacc agcatgaaat 4800

 tacttgacca agttgtccct ccagctggtg atgatgaggt aaccgtgggg 4850

 aagttctatg ccactttcct gatacaggac tactttagga aattcaagaa 4900

 acggaaagaa caaggactgg tgggaaagta ccctgcgaag aacaccacaa 4950

 ttgccctaca ggcgggatta aggacactgc atgacattgg gccagaaatc 5000

 cggcgtgcta tatcgtgtga tttgcaagat gacgagcctg aggaaacaaa 5050

 acgagaagaa gaagatgatg tgttcaaaag aaatggtgcc ctgcttggaa 5100

 accatgtcaa tcatgttaat agtgatagga gagattccct tcagcagacc 5150

 aataccaccc accgtcccct gcatgtccaa aggccttcaa ttccacctgc 5200

 aagtgatact gagaaaccgc tgtttcctcc agcaggaaat tcggtgtgtc 5250

 ataaccatca taaccataat tccataggaa agcaagttcc cacctcaaca 5300

 aatgccaatc tcaataatgc caatatgtcc aaagctgccc atggaaagcg 5350

 gcccagcatt gggaaccttg agcatgtgtc tgaaaatggg catcattctt 5400

 cccacaagca tgaccgggag cctcagagaa ggtccagtgt gaaaagaacc 5450

 cgctattatg aaacttacat taggtccgac tcaggagatg aacagctccc 5500

 aactatttgc cgggaagacc cagagataca tggctatttc agggaccccc 5550

 actgcttggg ggagcaggag tatttcagta gtgaggaatg ctacgaggat 5600

 gacagctcgc ccacctggag caggcaaaac tatggctact acagcagata 5650

 cccaggcaga aacatcgact ctgagaggcc ccgaggctac catcatcccc 5700

 aaggattctt ggaggacgat gactcgcccg tttgctatga ttcacggaga 5750

 tctccaagga gacgcctact acctcccacc ccagcatccc accggagatc 5800

 ctccttcaac tttgagtgcc tgcgccggca gagcagccag gaagaggtcc 5850

 cgtcgtctcc catcttcccc catcgcacgg ccctgcctct gcatctaatg 5900

 cagcaacaga tcatggcagt tgccggccta gattcaagta aagcccagaa 5950

 gtactcaccg agtcactcga cccggtcgtg gggccacccc tccagcaacc 6000

 cctccctacc gggactggac accgtgctac acccccctga tccaagtgga 6050

 gcagtcagag gccctggacc aggtgaacgg cagcctgccg tccctgcacc 6100

 gcagctcctg gtacacagac gagcccgaca tctcctaccg gactttcaca 6150

 ccagccagcc tgactgtccc cagcagcttc cggaacaaaa acagcgacaa 6200

 gcagaggagt gcggacagct tggtggaggc agtcctgata tccgaaggct 6250

 tgggacgcta tgcaagggac ccaaaatttg tgtcagcaac aaaacacgaa 6300

 atcgctgatg cctgtgacct caccatcgac gagatggaga gtgcagccag 6350

 caccctgctt aatgggaacg tgcgtccccg agccaacggg gatgtgggcc 6400

 cccctctcac accggcagga ctatgagcta caggactttg gtcctggcta 6450

 cagcgacgaa gagccagacc ctgggaggga tgaggaggac ctggcggatg 6500

 aaatgatatg catcaccacc ttgtagcccc cagcgagggg cagactggct 6550

 ctggcctcag gtggggcgca ggagagccag gggaaaagtg cctcatagtt 6600

 aggaaagttt aggcactagt tgggagtaat attcaattaa ttagactttt 6650

 gtataagaga tgtcatgcct caagaaagcc ataaacctgg taggaacagg 6700

 tcccaagcgg ttgagcctgg cagagtacca tgcgctcggc cccagctgca 6750

 ggaaacagca ggccccgccc tctcacagag gatgggtgag gaggccagac 6800

 ctgccctgcc ccattgtcca gatgggcact gctgtggagt ctgcttctcc 6850

 catgtaccag ggcaccaggc ccacccaact gaaggcatgg cggcggggtg 6900

 caggggaaag ttaaaggtga tgacgatcat cacacctgtg tcgttacctc 6950

 agccatcggt ctagcatatc agtcactggg cccaacatat ccatttttaa 7000

 accctttccc ccaaatacac tgcgtcctgg ttcctgttta gctgttctga 7050

 aatacggtgt gtaagtaagt cagaacccag ctaccagtga ttattgcgag 7100

 ggcaatggga cctcataaat aaggttttct gtgatgtgac gccagtttac 7150

 ataagagaat atcactccga tggtcggttt ctgactgtca cgctaagggc 7200

 aactgtaaac tggaataata atgcactcgc aaccaggtaa acttagatac 7250

 actagtttgt ttaaaattat agatttactg tacatgactt gtaatatact 7300

 ataatttgta tttgtaaaga gatggtctat attttgtaat tactgtattg 7350

 tatttgaact gcagcaatat ccatgggtcc taataattgt agttccccac 7400

 taaaatctag aaattattag tatttttact cgggctatcc agaagtagaa 7450

 gaaatagagc caattctcat ttattcagcg aaaatcctct ggggttaaaa 7500

 ttttaagttt gaaagaactt gacactacag aaatttttct aaaatatttt 7550

 gagtcactat aaacctatca tctttccaca agatatacca gatgactatt 7600

 tgcagtcttt tctttgggca agagttccat gattttgata ctgtaccttt 7650

 ggatccacca tgggttgcaa ctgtctttgg ttttgtttgt ttgacttgaa 7700

 ccaccctctg gtaagtaagt gaattacaga gcaggtccag ctggctgctc 7750

 tgccccttgg gtatccatag ttacggtttt ctctgtggcc cacccagggt 7800

 gttttttgca tcgctggtgc agaaatgcac aggtggatga gatatagctg 7850

 ctcttgtcct ctggggactg gtggtgctgc ttaagaaata aggggtgctg 7900

 gggac 7905

<210> 2173
<211> 2101
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 840-848
<223> unknown amino acid

<220>
<221> Unsure
<222> 2521-2545
<223> Unknown amino acid

<400> 2173
 Lys Met Gln His Gln Arg Gln Gln Gln Ala Asp His Ala Asn Glu
   1               5                  10                  15

 Ala Asn Tyr Ala Arg Gly Thr Arg Leu Pro Leu Ser Gly Glu Gly
                  20                  25                  30

 Pro Thr Ser Gln Pro Asn Ser Ser Lys Gln Thr Val Leu Ser Trp
                  35                  40                  45

 Gln Ala Ala Ile Asp Ala Ala Arg Gln Ala Lys Ala Ala Gln Thr
                  50                  55                  60

 Met Ser Thr Ser Ala Pro Pro Pro Val Gly Ser Leu Ser Gln Arg
                  65                  70                  75

 Lys Arg Gln Gln Tyr Ala Lys Ser Lys Lys Gln Gly Asn Ser Ser
                  80                  85                  90

 Asn Ser Arg Pro Ala Arg Ala Leu Phe Cys Leu Ser Leu Asn Asn
                  95                 100                 105

 Pro Ile Arg Arg Ala Cys Ile Ser Ile Val Glu Trp Lys Pro Phe
                 110                 115                 120

 Asp Ile Phe Ile Leu Leu Ala Ile Phe Ala Asn Cys Val Ala Leu
                 125                 130                 135

 Ala Ile Tyr Ile Pro Phe Pro Glu Asp Asp Ser Asn Ser Thr Asn
                 140                 145                 150

 His Asn Leu Glu Lys Val Glu Tyr Ala Phe Leu Ile Ile Phe Thr
                 155                 160                 165

 Val Glu Thr Phe Leu Lys Ile Ile Ala Tyr Gly Leu Leu Leu His
                 170                 175                 180

 Pro Asn Ala Tyr Val Arg Asn Gly Trp Asn Leu Leu Asp Phe Val
                 185                 190                 195

 Ile Val Ile Val Gly Leu Phe Ser Val Ile Leu Glu Gln Leu Thr
                 200                 205                 210

 Lys Glu Thr Glu Gly Gly Asn His Ser Ser Gly Lys Ser Gly Gly
                 215                 220                 225

 Phe Asp Val Lys Ala Leu Arg Ala Phe Arg Val Leu Arg Pro Leu
                 230                 235                 240

 Arg Leu Val Ser Gly Val Pro Ser Leu Gln Val Val Leu Asn Ser
                 245                 250                 255

 Ile Ile Lys Ala Met Val Pro Leu Leu His Ile Ala Leu Leu Val
                 260                 265                 270

 Leu Phe Val Ile Ile Ile Tyr Ala Ile Ile Gly Leu Glu Leu Phe
                 275                 280                 285

 Ile Gly Lys Met His Lys Thr Cys Phe Phe Ala Asp Ser Asp Ile
                 290                 295                 300

 Val Ala Glu Glu Asp Pro Ala Pro Cys Ala Phe Ser Gly Asn Gly
                 305                 310                 315

 Arg Gln Cys Thr Ala Asn Gly Thr Glu Cys Arg Ser Gly Trp Val
                 320                 325                 330

 Gly Pro Asn Gly Gly Ile Thr Asn Phe Asp Asn Phe Ala Phe Ala
                 335                 340                 345

 Met Leu Thr Val Phe Gln Cys Ile Thr Met Glu Gly Trp Thr Asp
                 350                 355                 360

 Val Leu Tyr Trp Val Asn Asp Ala Ile Gly Trp Glu Trp Pro Trp
                 365                 370                 375

 Val Tyr Phe Val Ser Leu Ile Ile Leu Gly Ser Phe Phe Val Leu
                 380                 385                 390

 Asn Leu Val Leu Gly Val Leu Ser Gly Glu Phe Ser Lys Glu Arg
                 395                 400                 405

 Glu Lys Ala Lys Ala Arg Gly Asp Phe Gln Lys Leu Arg Glu Lys
                 410                 415                 420

 Gln Gln Leu Glu Glu Asp Leu Lys Gly Tyr Leu Asp Trp Ile Thr
                 425                 430                 435

 Gln Ala Glu Asp Ile Asp Pro Glu Asn Glu Glu Glu Gly Gly Glu
                 440                 445                 450

 Glu Gly Lys Arg Asn Thr Ser Met Pro Thr Ser Glu Thr Glu Ser
                 455                 460                 465

 Val Asn Thr Glu Asn Val Ser Gly Glu Gly Glu Asn Arg Gly Cys
                 470                 475                 480

 Cys Gly Ser Leu Trp Cys Trp Trp Arg Arg Arg Gly Ala Ala Lys
                 485                 490                 495

 Ala Gly Pro Ser Gly Cys Arg Arg Trp Gly Gln Ala Ile Ser Lys
                 500                 505                 510

 Ser Lys Leu Ser Arg Arg Trp Arg Arg Trp Asn Arg Phe Asn Arg
                 515                 520                 525

 Arg Arg Cys Arg Ala Ala Val Lys Ser Val Thr Phe Tyr Trp Leu
                 530                 535                 540

 Val Ile Val Leu Val Phe Leu Asn Thr Leu Thr Ile Ser Ser Glu
                 545                 550                 555

 His Tyr Asn Gln Pro Asp Trp Leu Thr Gln Ile Gln Asp Ile Ala
                 560                 565                 570

 Asn Lys Val Leu Leu Ala Leu Phe Thr Cys Glu Met Leu Val Lys
                 575                 580                 585

 Met Tyr Ser Leu Gly Leu Gln Ala Tyr Phe Val Ser Leu Phe Asn
                 590                 595                 600

 Arg Phe Asp Cys Phe Val Val Cys Gly Gly Ile Thr Glu Thr Ile
                 605                 610                 615

 Leu Val Glu Leu Glu Ile Met Ser Pro Leu Gly Ile Ser Val Phe
                 620                 625                 630

 Arg Cys Val Arg Leu Leu Arg Ile Phe Lys Val Thr Arg His Trp
                 635                 640                 645

 Thr Ser Leu Ser Asn Leu Val Ala Ser Leu Leu Asn Ser Met Lys
                 650                 655                 660

 Ser Ile Ala Ser Leu Leu Leu Leu Leu Phe Leu Phe Ile Ile Ile
                 665                 670                 675

 Phe Ser Leu Leu Gly Met Gln Leu Phe Gly Gly Lys Phe Asn Phe
                 680                 685                 690

 Asp Glu Thr Gln Thr Lys Arg Ser Thr Phe Asp Asn Phe Pro Gln
                 695                 700                 705

 Ala Leu Leu Thr Val Phe Gln Ile Leu Thr Gly Glu Asp Trp Asn
                 710                 715                 720

 Ala Val Met Tyr Asp Gly Ile Met Ala Tyr Gly Gly Pro Ser Ser
                 725                 730                 735

 Ser Gly Met Ile Val Cys Ile Tyr Phe Ile Ile Leu Phe Ile Cys
                 740                 745                 750

 Gly Asn Tyr Ile Leu Leu Asn Val Phe Leu Ala Ile Ala Val Asp
                 755                 760                 765

 Asn Leu Ala Asp Ala Glu Ser Leu Asn Thr Ala Gln Lys Glu Glu
                 770                 775                 780

 Ala Glu Glu Lys Glu Arg Lys Lys Ile Ala Arg Lys Glu Ser Leu
                 785                 790                 795

 Glu Asn Lys Lys Asn Asn Lys Pro Glu Val Asn Gln Ile Ala Asn
                 800                 805                 810

 Ser Asp Asn Lys Val Thr Ile Asp Asp Tyr Arg Glu Glu Asp Glu
                 815                 820                 825

 Asp Lys Asp Pro Tyr Pro Pro Cys Asp Val Pro Val Gly Glu Xaa
                 830                 835                 840

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Pro Glu Val Pro Ala Gly Pro
                 845                 850                 855

 Arg Pro Arg Arg Ile Ser Glu Leu Asn Met Lys Glu Lys Ile Ala
                 860                 865                 870

 Pro Ile Pro Glu Gly Ser Ala Phe Phe Ile Leu Ser Lys Thr Asn
                 875                 880                 885

 Pro Ile Arg Val Gly Cys His Lys Leu Ile Asn His His Ile Phe
                 890                 895                 900

 Thr Asn Leu Ile Leu Val Phe Ile Met Leu Ser Ser Ala Ala Leu
                 905                 910                 915

 Ala Ala Glu Asp Pro Ile Arg Ser His Ser Phe Arg Asn Thr Ile
                 920                 925                 930

 Leu Gly Tyr Phe Asp Tyr Ala Phe Thr Ala Ile Phe Thr Val Glu
                 935                 940                 945

 Ile Leu Leu Lys Met Thr Thr Phe Gly Ala Phe Leu His Lys Gly
                 950                 955                 960

 Ala Phe Cys Arg Asn Tyr Phe Asn Leu Leu Asp Met Leu Val Val
                 965                 970                 975

 Gly Val Ser Leu Val Ser Phe Gly Ile Gln Ser Ser Ala Ile Ser
                 980                 985                 990

 Val Val Lys Ile Leu Arg Val Leu Arg Val Leu Arg Pro Leu Arg
                 995                1000                1005

 Ala Ile Asn Arg Ala Lys Gly Leu Lys His Val Val Gln Cys Val
                1010                1015                1020

 Phe Val Ala Ile Arg Thr Ile Gly Asn Ile Met Ile Val Thr Thr
                1025                1030                1035

 Leu Leu Gln Phe Met Phe Ala Cys Ile Gly Val Gln Leu Phe Lys
                1040                1045                1050

 Gly Lys Phe Tyr Arg Cys Thr Asp Glu Ala Lys Ser Asn Pro Glu
                1055                1060                1065

 Glu Cys Arg Gly Leu Phe Ile Leu Tyr Lys Asp Gly Asp Val Asp
                1070                1075                1080

 Ser Pro Val Val Arg Glu Arg Ile Trp Gln Asn Ser Asp Phe Asn
                1085                1090                1095

 Phe Asp Asn Val Leu Ser Ala Met Met Ala Leu Phe Thr Val Ser
                1100                1105                1110

 Thr Phe Glu Gly Trp Pro Ala Leu Leu Tyr Lys Ala Ile Asp Ser
                1115                1120                1125

 Asn Gly Glu Asn Ile Gly Pro Ile Tyr Asn His Arg Val Glu Ile
                1130                1135                1140

 Ser Ile Phe Phe Ile Ile Tyr Ile Ile Ile Val Ala Phe Phe Met
                1145                1150                1155

 Met Asn Ile Phe Val Gly Phe Val Ile Val Thr Phe Gln Glu Gln
                1160                1165                1170

 Gly Glu Lys Glu Tyr Lys Asn Cys Glu Leu Asp Lys Asn Gln Arg
                1175                1180                1185

 Gln Cys Val Glu Tyr Ala Leu Lys Ala Arg Pro Leu Arg Arg Tyr
                1190                1195                1200

 Ile Pro Lys Asn Pro Tyr Gln Tyr Lys Phe Trp Tyr Val Val Asn
                1205                1210                1215

 Ser Ser Pro Phe Glu Tyr Met Met Phe Val Leu Ile Met Leu Asn
                1220                1225                1230

 Thr Leu Cys Leu Ala Met Gln His Tyr Glu Gln Ser Lys Met Phe
                1235                1240                1245

 Asn Asp Ala Met Asp Ile Leu Asn Met Val Phe Thr Gly Val Phe
                1250                1255                1260

 Thr Val Glu Met Val Leu Lys Val Ile Ala Phe Lys Pro Lys Gly
                1265                1270                1275

 Tyr Phe Ser Asp Ala Trp Asn Thr Phe Asp Ser Leu Ile Val Ile
                1280                1285                1290

 Gly Ser Ile Ile Asp Val Ala Leu Ser Glu Ala Asp Pro Thr Glu
                1295                1300                1305

 Ser Glu Asn Val Pro Val Pro Thr Ala Thr Pro Gly Asn Ser Glu
                1310                1315                1320

 Glu Ser Asn Arg Ile Ser Ile Thr Phe Phe Arg Leu Phe Arg Val
                1325                1330                1335

 Met Arg Leu Val Lys Leu Leu Ser Arg Gly Glu Gly Ile Arg Thr
                1340                1345                1350

 Leu Leu Trp Thr Phe Ile Lys Ser Phe Gln Ala Leu Pro Tyr Val
                1355                1360                1365

 Ala Leu Leu Ile Ala Met Leu Phe Phe Ile Tyr Ala Val Ile Gly
                1370                1375                1380

 Met Gln Met Phe Gly Lys Val Ala Met Arg Asp Asn Asn Gln Ile
                1385                1390                1395

 Asn Arg Asn Asn Asn Phe Gln Thr Phe Pro Gln Ala Val Leu Leu
                1400                1405                1410

 Leu Phe Arg Cys Ala Thr Gly Glu Ala Trp Gln Glu Ile Met Leu
                1415                1420                1425

 Ala Cys Leu Pro Gly Lys Leu Cys Asp Pro Glu Ser Asp Tyr Asn
                1430                1435                1440

 Pro Gly Glu Glu Tyr Thr Cys Gly Ser Asn Phe Ala Ile Val Tyr
                1445                1450                1455

 Phe Ile Ser Phe Tyr Met Leu Cys Ala Phe Leu Ile Ile Asn Leu
                1460                1465                1470

 Phe Val Ala Val Ile Met Asp Asn Phe Asp Tyr Leu Thr Arg Asp
                1475                1480                1485

 Trp Ser Ile Leu Gly Pro His His Leu Asp Glu Phe Lys Arg Ile
                1490                1495                1500

 Trp Ser Glu Tyr Asp Pro Glu Ala Lys Gly Arg Ile Lys His Leu
                1505                1510                1515

 Asp Val Val Thr Leu Leu Arg Arg Ile Gln Pro Pro Leu Gly Phe
                1520                1525                1530

 Gly Lys Leu Cys Pro His Arg Val Ala Cys Lys Arg Leu Val Ala
                1535                1540                1545

 Met Asn Met Pro Leu Asn Ser Asp Gly Thr Val Met Phe Asn Ala
                1550                1555                1560

 Thr Leu Phe Ala Leu Val Arg Thr Ala Leu Lys Ile Lys Thr Glu
                1565                1570                1575

 Gly Asn Leu Glu Gln Ala Asn Glu Glu Leu Arg Ala Val Ile Lys
                1580                1585                1590

 Lys Ile Trp Lys Lys Thr Ser Met Lys Leu Leu Asp Gln Val Val
                1595                1600                1605

 Pro Pro Ala Gly Asp Asp Glu Val Thr Val Gly Lys Phe Tyr Ala
                1610                1615                1620

 Thr Phe Leu Ile Gln Asp Tyr Phe Arg Lys Phe Lys Lys Arg Lys
                1625                1630                1635

 Glu Gln Gly Leu Val Gly Lys Tyr Pro Ala Lys Asn Thr Thr Ile
                1640                1645                1650

 Ala Leu Gln Ala Gly Leu Arg Thr Leu His Asp Ile Gly Pro Glu
                1655                1660                1665

 Ile Arg Arg Ala Ile Ser Cys Asp Leu Gln Asp Asp Glu Pro Glu
                1670                1675                1680

 Glu Thr Lys Arg Glu Glu Glu Asp Asp Val Phe Lys Arg Asn Gly
                1685                1690                1695

 Ala Leu Leu Gly Asn His Val Asn His Val Asn Ser Asp Arg Arg
                1700                1705                1710

 Asp Ser Leu Gln Gln Thr Asn Thr Thr His Arg Pro Leu His Val
                1715                1720                1725

 Gln Arg Pro Ser Ile Pro Pro Ala Ser Asp Thr Glu Lys Pro Leu
                1730                1735                1740

 Phe Pro Pro Ala Gly Asn Ser Val Cys His Asn His His Asn His
                1745                1750                1755

 Asn Ser Ile Gly Lys Gln Val Pro Thr Ser Thr Asn Ala Asn Leu
                1760                1765                1770

 Asn Asn Ala Asn Met Ser Lys Ala Ala His Gly Lys Arg Pro Ser
                1775                1780                1785

 Ile Gly Asn Leu Glu His Val Ser Glu Asn Gly His His Ser Ser
                1790                1795                1800

 His Lys His Asp Arg Glu Pro Gln Arg Arg Ser Ser Val Lys Arg
                1805                1810                1815

 Thr Arg Tyr Tyr Glu Thr Tyr Ile Arg Ser Asp Ser Gly Asp Glu
                1820                1825                1830

 Gln Leu Pro Thr Ile Cys Arg Glu Asp Pro Glu Ile His Gly Tyr
                1835                1840                1845

 Phe Arg Asp Pro His Cys Leu Gly Glu Gln Glu Tyr Phe Ser Ser
                1850                1855                1860

 Glu Glu Cys Tyr Glu Asp Asp Ser Ser Pro Thr Trp Ser Arg Gln
                1865                1870                1875

 Asn Tyr Gly Tyr Tyr Ser Arg Tyr Pro Gly Arg Asn Ile Asp Ser
                1880                1885                1890

 Glu Arg Pro Arg Gly Tyr His His Pro Gln Gly Phe Leu Glu Asp
                1895                1900                1905

 Asp Asp Ser Pro Val Cys Tyr Asp Ser Arg Arg Ser Pro Arg Arg
                1910                1915                1920

 Arg Leu Leu Pro Pro Thr Pro Ala Ser His Arg Arg Ser Ser Phe
                1925                1930                1935

 Asn Phe Glu Cys Leu Arg Arg Gln Ser Ser Gln Glu Glu Val Pro
                1940                1945                1950

 Ser Ser Pro Ile Phe Pro His Arg Thr Ala Leu Pro Leu His Leu
                1955                1960                1965

 Met Gln Gln Gln Ile Met Ala Val Ala Gly Leu Asp Ser Ser Lys
                1970                1975                1980

 Ala Gln Lys Tyr Ser Pro Ser His Ser Thr Arg Ser Trp Gly His
                1985                1990                1995

 Pro Ser Ser Asn Pro Ser Leu Pro Gly Leu Asp Thr Val Leu His
                2000                2005                2010

 Pro Pro Asp Pro Ser Gly Ala Val Arg Gly Pro Gly Pro Gly Glu
                2015                2020                2025

 Arg Gln Pro Ala Val Pro Ala Pro Gln Leu Leu Val His Arg Arg
                2030                2035                2040

 Ala Arg His Leu Leu Pro Asp Phe His Thr Ser Gln Pro Asp Cys
                2045                2050                2055

 Pro Gln Gln Leu Pro Glu Gln Lys Gln Arg Gln Ala Glu Glu Cys
                2060                2065                2070

 Gly Gln Leu Gly Gly Gly Ser Pro Asp Ile Arg Arg Leu Gly Thr
                2075                2080                2085

 Leu Cys Lys Gly Pro Lys Ile Cys Val Ser Asn Lys Thr Arg Asn
                2090                2095                2100

 Arg


<210> 2174
<211> 1897
<212> DNA
<213> Homo sapien

<400> 2174
 gtttgatttt tgtgggcctt acttttccca tttgctcatg tatgtctata 50

 ttcctatatc taatgtttct taaaagacaa atctgactgt gtaggtgcat 100

 ttgtttaaaa aatataactc cccattgcct ctgggataaa gtcttatctc 150

 agtttacata tattcttgat aacctctcca actttatgtc tcaccacccc 200

 cactcacttc gtaattcgtg ccttatcaga atggacctgt tatactggca 250

 gttcaccata tataccatta cattttgttt ctcccatctc tcaggtagac 300

 ttacactttc ggcccagcac atcagtcatc gcccttgctt gctttcctat 350

 tcactcctgt tctggaaggt gcaccacctt ttcttggaag gcttcccttg 400

 ctctcccagg ctagatgaga tgtccttcca tcagttccca cagcaccctg 450

 tgcatgtatc tgttgtgcac ttaccaatag tatacaaggg atctatgacc 500

 caagtctctc cccactagct tgtaagctcc tcacagacag gaaccatgtt 550

 ttgtctttgt actccagtgc ctagtatata agagatactc aataaataaa 600

 tatttgtcaa atcaactaat tgattccttg tgacctaatt ctagagaatg 650

 ggaagaaggc ctgttatttt gttgtccttt atggttcttt aggaaagctc 700

 tccaagcttg gcatttgtca gggtgggagg aaaactgttg aagtattaag 750

 actggacaca tggctgctaa ttcatcagct tatcattgaa aaagtccata 800

 gccaaaacct gactgtgcac ttactatagg accctgacct gcctgggtct 850

 ccctgtctct ccagccagta tatttaaagg taatgagata atgatgagtg 900

 ttttgaaaaa tgtttagtgt tcaaatagaa accattcgtg tcccttcact 950

 ctctgaacat agtctgcaaa tctctccctc tctggtatgt ttctgttttg 1000

 tggattagac tgctaaataa gcgaagagtt aattttgaag ttcaggtcaa 1050

 caaattcctg tttggagacg ggctgttcct gaataccagg ttgttatctg 1100

 tctattacag ccccttcact tctgggctcc tggccctttg cgaagtactt 1150

 cagaaagcct agagagaaga gagggccctc aaatcccatt ccagccccta 1200

 aatgaaagtg gcatcacaag gagaaaagtg gaggtagaaa tgtaccatgg 1250

 gggacgttgc cccattgcct ttcttcccct gactactggg cttcctctat 1300

 cagcttttaa cgcctggaag tagctgagtc tccagtcact ggtggccttc 1350

 cccaagtgag ctcagcagca tgtgctaata ggtgccaata ctgtgctggc 1400

 tccagtggga ttcctctctg caaagctgct ggcttagctt gactgtttcc 1450

 ctattcctct ccttagaact ttcatagcca gtcaagcata gaattgcatc 1500

 cattcttctg aaataggtac tgtgcctaat ttttcattgg cttggccaag 1550

 attctgttac ctgtaattat gtcatatggg ctgactggtg taggtttggt 1600

 aggcctcact gctctccaga ggctagtgtt cctatcccag gatggctgtt 1650

 gggattagga gtggaatgag gaatagttta ggaccacaag agatttggcc 1700

 tccttggaac atgtaggaag gcctcaagga tgtaattcta gcccagggaa 1750

 gaaaatcctt ttcagcagac gcttcccttc ccttccccta gggaatgtgt 1800

 ccctactata gtaaactctt ccttaagaga gttttatgtt ttctctgtca 1850

 gatcaatttg tttttcttaa tgttgttcct atcaaaaaaa aaaaaaa 1897

<210> 2175
<211> 110
<212> PRT
<213> Homo sapien

<400> 2175
 Met Ser His His Pro His Ser Leu Arg Asn Ser Cys Leu Ile Arg
   1               5                  10                  15

 Met Asp Leu Leu Tyr Trp Gln Phe Thr Ile Tyr Thr Ile Thr Phe
                  20                  25                  30

 Cys Phe Ser His Leu Ser Gly Arg Leu Thr Leu Ser Ala Gln His
                  35                  40                  45

 Ile Ser His Arg Pro Cys Leu Leu Ser Tyr Ser Leu Leu Phe Trp
                  50                  55                  60

 Lys Val His His Leu Phe Leu Glu Gly Phe Pro Cys Ser Pro Arg
                  65                  70                  75

 Leu Asp Glu Met Ser Phe His Gln Phe Pro Gln His Pro Val His
                  80                  85                  90

 Val Ser Val Val His Leu Pro Ile Val Tyr Lys Gly Ser Met Thr
                  95                 100                 105

 Gln Val Ser Pro His
                 110

<210> 2176
<211> 2530
<212> DNA
<213> Homo sapien

<400> 2176
 aaatccttct tccaatgttc ctcccctctc tgtatgaacc ctgtgttggg 50

 gggcagaaga tggaagccct tggcaagctc gatcgaacca agctactaaa 100

 ttgctgagct cgttttaact gaagtgtgag aaggaggttt aaggcaagta 150

 gacaacatcc tgttgttggg gtgcttctct cttttttgca catctggctg 200

 aactgggagt caggtggttg acttgtgcct ggctgcagta gcagcggcat 250

 ctcccttgca cagttctcct cctcggcctg cccaagagtc caccaggcca 300

 tggacgcagt ggctgtgtat catggcaaaa tcagcaggga aaccggcgag 350

 aagctcctgc ttgccactgg gctggatggc agctatttgc tgagggacag 400

 cgagagcgtg ccaggcgtgt actgcctatg tgtgctgtat cacggttaca 450

 tttatacata ccgagtgtcc cagacagaaa caggttcttg gagtgctgag 500

 acagcacctg gggtacataa aagatatttc cggaaaataa aaaatctcat 550

 ttcagcattt cagaagccag atcaaggcat tgtaatacct ctgcagtatc 600

 cagttgagaa gaagtcctca gctagaagta cacaaggtac tacagggata 650

 agagaagatc ctgatgtctg cctgaaagcc ccatgaagaa aaataaaaca 700

 ccttgtactt tattttctat aatttaaata tatgctaagt cttatatatt 750

 gtagataata cagttcggtg agctacaaat gcatttctaa agccattgta 800

 gtcctgtaat ggaagcatct agcatgtcgt caaagctgaa atggactttt 850

 gtacatagtg aggagctttg aaacgaggat tgggaaaaag taattccgta 900

 ggttattttc agttattata tttacaaatg ggaaacaaaa ggataatgaa 950

 tactttataa aggattaatg tcaattcttg ccaaatataa ataaaaataa 1000

 tcctcagttt ttgtgaaaag ctccattttt agtgaaatat tattttatag 1050

 ctactaattt taaaatgtct tgcttgattg tatggtggga agttggctgg 1100

 tgtcccttgt ctttgccaag ttctccacta gctatggtgt cataggctct 1150

 tttgggattt ttgaagctgt atactgtgtg ctaaaacaag cactaaacaa 1200

 agagtgaagg atttatgttt aattctgaaa gcaaccttct tgcctagtgt 1250

 tctgatattg gacagtaaaa tccacagacc aacctggagt tgaaaatctt 1300

 ataatttaaa atatgctcta aacatgttta tcgtatttga tgctacagga 1350

 tttgaaattg tattacaaat ccaatgaaat gagtttttct tttcatttac 1400

 ctctgcccca gttgtttcta ctacatggaa gacctcattt tgaagggaaa 1450

 tttcagcagc tgcagctcat gagtaactga tttgtaacaa gcctcctttt 1500

 aaagtaaccc tacaaaacca ctggaaagtt tatggttgta ttatttttta 1550

 aaaaaattcc aagtgattga aacctacacg agatacagaa ttttatgcgg 1600

 cattttcttc tcacatttat atttttgtga ttttgtgatt gattatatgt 1650

 cactttgcta cagggctcac agaattcatt cactcaacaa acataatagg 1700

 gcgctgaggg catagaagta aaaacacctg gtccctgctc tcagttcact 1750

 gtcttgttgg acgagaaaag aaacaataac gataaaagac agtgaaagaa 1800

 aataacgata aaagacagtg aaagaaaata acaataaaag acaaggaaaa 1850

 aataacaatg aaagttgata agtacatgat aagcgaggtt ccccgtgtgt 1900

 aggtagatct ggtctttaga ggcagataga taggtcagtg caaatactct 1950

 ggtccatggg ccatatgaaa aggctaagct tcactgtaaa ataataactg 2000

 ggaattctgg attgtgtatg ggtgttggtg aacttggttt taattagtga 2050

 actgctgaga gacagagcta ttctccatgt actggcaaga cctgatttct 2100

 gagcatttaa tatggatgcc gtgggagtac aaaagtggag tgtggcctga 2150

 gtaatgcatt atgggtggtt taccatttct tgaggtaaaa gcatcacatg 2200

 aacttgtaaa ggaatttaaa aatcctactt tcataataag ttgcataggt 2250

 ttaataattt ttaattatat ggcttgagtt taaattgtaa taggcgtaac 2300

 taattttaac tctataatgt gttcattctg gaataatcct aaacatatga 2350

 attatgtttg catgttcact tccaagagcc tttttttgaa aaaaagcttt 2400

 ttttgaatca tcaagtcttt cacatttaaa taaagtgttt gaaagcttta 2450

 tttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2500

 aaaaaaaaaa aaaaaaaaaa aagaaaaaaa 2530

<210> 2177
<211> 128
<212> PRT
<213> Homo sapien

<400> 2177
 Met Asp Ala Val Ala Val Tyr His Gly Lys Ile Ser Arg Glu Thr
   1               5                  10                  15

 Gly Glu Lys Leu Leu Leu Ala Thr Gly Leu Asp Gly Ser Tyr Leu
                  20                  25                  30

 Leu Arg Asp Ser Glu Ser Val Pro Gly Val Tyr Cys Leu Cys Val
                  35                  40                  45

 Leu Tyr His Gly Tyr Ile Tyr Thr Tyr Arg Val Ser Gln Thr Glu
                  50                  55                  60

 Thr Gly Ser Trp Ser Ala Glu Thr Ala Pro Gly Val His Lys Arg
                  65                  70                  75

 Tyr Phe Arg Lys Ile Lys Asn Leu Ile Ser Ala Phe Gln Lys Pro
                  80                  85                  90

 Asp Gln Gly Ile Val Ile Pro Leu Gln Tyr Pro Val Glu Lys Lys
                  95                 100                 105

 Ser Ser Ala Arg Ser Thr Gln Gly Thr Thr Gly Ile Arg Glu Asp
                 110                 115                 120

 Pro Asp Val Cys Leu Lys Ala Pro
                 125

<210> 2178
<211> 2086
<212> DNA
<213> Homo sapien

<400> 2178
 ccgccgccgc gcgccagaga gaagcagcct ccggccgcgg cggcccctgt 50

 ctcccgaccc cggaaggcga agcaggctgc ccggggaccc cgcgcgtggg 100

 cgcttgaagc cgagaccagc ctgcccgggc ctgggcaggc ggagcagggc 150

 cttggacccc gcggcgcccc tcggcctcgg agcaacgagc gcagcgccgc 200

 ctctgaagag ccaatccatt caggatggga aaccacgcag gcaaacgaga 250

 attaaatgcc gagaaggcca gtacgaatag tgaaactaac agaggagaat 300

 ctgaaaaaaa gagaaacctg ggtgaacttt cacggacaac ctcagaggac 350

 aacgaagtgt tcggagaggc agatgcgaac cagaacaatg ggacctcctc 400

 tcaggacaca gcggtgactg actccaagcg cacagcggac ccgaagaatg 450

 cctggcagga tgcccaccca gctgacccag ggagccgccc ccacttgatc 500

 cgcctctttt cccgagatgc cccggggagg gaggacaaca ccttcaaaga 550

 caggccctct gagtccgacg agctccagac catccaagaa gacagtgcag 600

 ccacctccga gagcctggat gtgatggcgt cacagaagag accctcccag 650

 aggcacggat ccaagtacct ggccacagca agtaccatgg accatgccag 700

 gcatggcttc ctcccaaggc acagagacac gggcatcctt gactccatcg 750

 ggcgcttctt tggcggtgac aggggtgcgc ccaagcgggg ctctggcaag 800

 gtgagctctg aggagtagag gagttttagt ttaaatggaa aaagcaaagg 850

 agaaatcagt aggtgaactc agccattaga ggaagaactg gcacgtagcc 900

 tcttgctgtc taaggtctcg ttccgtgctg gagaatgcat atgagcccaa 950

 gagtgtgggc ctgagtggct gcttaggacg ttttcgttta actcaccccc 1000

 tcttttcctc acaagggatg gtggccgggg tgtggctcag gaatgtaagg 1050

 acatgctgaa ttctggatct ctaagggtgc ctggacatgg gcgttgcaga 1100

 aagagagcca cattctcagg gtctctggtg gtgtgtgctt gcggacttga 1150

 tgactgatgt tgcctctgca gcccacacgc tggggttcaa cactgggtta 1200

 tgctcgtttt ttcctggagt cagtgctgct agcttcatgt tgctctgcga 1250

 caatcatagg attgaggtcg aggaagactt ttgaacaaac tcctcaattt 1300

 aaatccgcct tgagcaaacg ttctctgtgg tctgagaagt ggaagggggg 1350

 agggataaat gagtgtctat gaatcaaagc tttattatct tgtgattcca 1400

 ttaatttgca tacagagtct tagaagtttc tttattcaaa agcaaatgtg 1450

 gataaaaatg tattacaaaa aaaaaaaaac tctgctatgg ggtccagagt 1500

 ctaggagggg ttcctgcagt tgattggtca gtggagaacc tgtggctgct 1550

 ggttcatcaa agcgctggtc cctgagtgcc attcagattg cagatgcagt 1600

 atttaacgtg atgtttagag tgttgggggg tggtgtaatt tgggagagaa 1650

 agaagttttt cccaaaaaag tccctagttt atggggtgtt ctcacacaac 1700

 ctgtaagatg aagctgtttt tctgcctgtg tgcagggctg attctggaat 1750

 tccagaaggc cttgtgggag cgtaaaaggc tttggaataa cgtgtggaac 1800

 agagcgcctc attctgataa catgcaatca taaaaaccat agggcaactg 1850

 ggagttaagg agtttctaga attggcttta gtctccaact gcaattcttt 1900

 attgatcatg aaattgttga agagaaacac aaatgtcagt tttacctttc 1950

 ctgtgggcgt gaaagcacat cgaagtttca ggcaactgtt aacatctcta 2000

 ccatctgtct gagttgagat ttcaggttgt gacacttgcc gtgacttatt 2050

 tgtaaatgac attttgtgtg tcttagatac taatgg 2086

<210> 2179
<211> 197
<212> PRT
<213> Homo sapien

<400> 2179
 Met Gly Asn His Ala Gly Lys Arg Glu Leu Asn Ala Glu Lys Ala
   1               5                  10                  15

 Ser Thr Asn Ser Glu Thr Asn Arg Gly Glu Ser Glu Lys Lys Arg
                  20                  25                  30

 Asn Leu Gly Glu Leu Ser Arg Thr Thr Ser Glu Asp Asn Glu Val
                  35                  40                  45

 Phe Gly Glu Ala Asp Ala Asn Gln Asn Asn Gly Thr Ser Ser Gln
                  50                  55                  60

 Asp Thr Ala Val Thr Asp Ser Lys Arg Thr Ala Asp Pro Lys Asn
                  65                  70                  75

 Ala Trp Gln Asp Ala His Pro Ala Asp Pro Gly Ser Arg Pro His
                  80                  85                  90

 Leu Ile Arg Leu Phe Ser Arg Asp Ala Pro Gly Arg Glu Asp Asn
                  95                 100                 105

 Thr Phe Lys Asp Arg Pro Ser Glu Ser Asp Glu Leu Gln Thr Ile
                 110                 115                 120

 Gln Glu Asp Ser Ala Ala Thr Ser Glu Ser Leu Asp Val Met Ala
                 125                 130                 135

 Ser Gln Lys Arg Pro Ser Gln Arg His Gly Ser Lys Tyr Leu Ala
                 140                 145                 150

 Thr Ala Ser Thr Met Asp His Ala Arg His Gly Phe Leu Pro Arg
                 155                 160                 165

 His Arg Asp Thr Gly Ile Leu Asp Ser Ile Gly Arg Phe Phe Gly
                 170                 175                 180

 Gly Asp Arg Gly Ala Pro Lys Arg Gly Ser Gly Lys Val Ser Ser
                 185                 190                 195

 Glu Glu


<210> 2180
<211> 928
<212> DNA
<213> Homo sapien

<400> 2180
 gctgtggccc tggcacctgc ccctgggctg ggacagccca ctgttccatg 50

 ctgcccaaga aggctcagca caggcacaaa ccattgcccg gcactggccc 100

 gtgctgcctg agaaggattg gcacgggcac agaccactgc ccccacctgc 150

 cctgcgccat ctacccaaga aggctcggca cgggcaccaa ccactgcctc 200

 caactgcccc atgctgcctg agaaggcact gcacggccac ccccaactgc 250

 cccgcactgt ccctacccgg gcagccatgc gagcggctgg aactctgctg 300

 gccttctgct gcctggtctt gagcaccact gggggccctt ccccagatac 350

 ttgttcccag gaccttaact cacgtgtgaa gccaggattt cctaaaacaa 400

 taaagaccaa tgacccagga gtcctccaag cagccagata cagtgttgaa 450

 aagttcaaca actgcacgaa cgacatgttc ttgttcaagg agtcccgcat 500

 cacaagggcc ctagttcaga tagtgaaagg cctgaaatat atgctggagg 550

 tggaaattgg cagaactacc tgcaagaaaa accagcacct gcgtctggat 600

 gactgtgact tccaaaccaa ccacaccttg aagcagactc tgagctgcta 650

 ctctgaagtc tgggtcgtgc cctggctcca gcacttcgag gtgcctgttc 700

 tccgttgtca ctgacccccg cctcttcagc aagaccacag ccatgacaaa 750

 caccaggatg catgctcctt gtcccctccc acccgcctca tgacccagcc 800

 tcacagaccc tctcaggcct ctgacgagtg agcgggtgaa gtgccactgg 850

 gtcaccgcag ggcagctgga atggcagcat ggtagcacct cctaacagat 900

 taaatagatc acatttgctt ctaaaatt 928

<210> 2181
<211> 167
<212> PRT
<213> Homo sapien

<400> 2181
 Met Leu Pro Glu Lys Ala Leu His Gly His Pro Gln Leu Pro Arg
   1               5                  10                  15

 Thr Val Pro Thr Arg Ala Ala Met Arg Ala Ala Gly Thr Leu Leu
                  20                  25                  30

 Ala Phe Cys Cys Leu Val Leu Ser Thr Thr Gly Gly Pro Ser Pro
                  35                  40                  45

 Asp Thr Cys Ser Gln Asp Leu Asn Ser Arg Val Lys Pro Gly Phe
                  50                  55                  60

 Pro Lys Thr Ile Lys Thr Asn Asp Pro Gly Val Leu Gln Ala Ala
                  65                  70                  75

 Arg Tyr Ser Val Glu Lys Phe Asn Asn Cys Thr Asn Asp Met Phe
                  80                  85                  90

 Leu Phe Lys Glu Ser Arg Ile Thr Arg Ala Leu Val Gln Ile Val
                  95                 100                 105

 Lys Gly Leu Lys Tyr Met Leu Glu Val Glu Ile Gly Arg Thr Thr
                 110                 115                 120

 Cys Lys Lys Asn Gln His Leu Arg Leu Asp Asp Cys Asp Phe Gln
                 125                 130                 135

 Thr Asn His Thr Leu Lys Gln Thr Leu Ser Cys Tyr Ser Glu Val
                 140                 145                 150

 Trp Val Val Pro Trp Leu Gln His Phe Glu Val Pro Val Leu Arg
                 155                 160                 165

 Cys His


<210> 2182
<211> 1424
<212> DNA
<213> Homo sapien

<400> 2182
 gaaggactgg ggaagactgg atgagaaggg tagaagaggg tgggtgtggg 50

 atggggaggg gagagtggaa aggccctggg cagaccctgg cagaaggggc 100

 acggggcagg gtgtgagttc cccactagca gggccaggtg agctatggtg 150

 ctgcacctac tgctcttctt gctgctgacc ccacagggtg ggcacagctg 200

 ccaggggctg gagctggccc gggaacttgt tctggccaag gtgagggccc 250

 tgttcttgga tgccttgggg ccccccgcgg tgaccaggga aggtggggac 300

 cctggagtca ggcggctgcc ccgaagacat gccctggggg gcttcacaca 350

 caggggctct gagcccgagg aagaggagga tgtctcccaa gccatccttt 400

 tcccagccac agatgccagc tgtgaggaca agtcagctgc cagagggctg 450

 gcccaggagg ctgaggaggg cctcttcaga tacatgttcc ggccatccca 500

 gcatacacgc agccgccagg tgacttcagc ccagctgtgg ttccacaccg 550

 ggctggacag gcagggcaca gcagcctcca atagctctga gcccctgcta 600

 ggcctgctgg cactgtcacc gggaggaccc gtggctgtgc ccatgtcttt 650

 gggccatgct ccccctcact gggccgtgct gcacctggcc acctctgctc 700

 tctctctgct gacccacccc gtcctggtgc tgctgctgcg ctgtcccctc 750

 tgtacctgct cagcccggcc tgaggccacg cccttcctgg tggcccacac 800

 tcggaccaga ccacccagtg gaggggagag agcccgacgc tcaactcccc 850

 tgatgtcctg gccttggtct ccctctgctc tgcgcctgct gcagaggcct 900

 ccggaggaac cggctgccca tgccaactgc cacagagtag cactgaacat 950

 ctccttccag gagctgggct gggaacggtg gatcgtgtac cctcccagtt 1000

 tcatcttcca ctactgtcat ggtggttgtg ggctgcacat cccaccaaac 1050

 ctgtcccttc cagtccctgg ggctccccct accccagccc agccctactc 1100

 cttgctgcca ggggcccagc cctgctgtgc tgctctccca gggaccatga 1150

 ggcccctaca tgtccgcacc acctcggatg gaggttactc tttcaagtat 1200

 gagacagtgc ccaaccttct cacgcagcac tgtgcttgta tctaagggtg 1250

 gggggtcttc cttcttaatc ccatggctgg tggccacgcc cccaccatca 1300

 tcagctggga ggaaaggcag agttgggaaa tagatggctc ccactcctcc 1350

 ctcctttcac ttctctgcct atgggctacc ctccccaccc cacttctatc 1400

 tcaataaaga acacagtgca tatg 1424

<210> 2183
<211> 366
<212> PRT
<213> Homo sapien

<400> 2183
 Met Val Leu His Leu Leu Leu Phe Leu Leu Leu Thr Pro Gln Gly
   1               5                  10                  15

 Gly His Ser Cys Gln Gly Leu Glu Leu Ala Arg Glu Leu Val Leu
                  20                  25                  30

 Ala Lys Val Arg Ala Leu Phe Leu Asp Ala Leu Gly Pro Pro Ala
                  35                  40                  45

 Val Thr Arg Glu Gly Gly Asp Pro Gly Val Arg Arg Leu Pro Arg
                  50                  55                  60

 Arg His Ala Leu Gly Gly Phe Thr His Arg Gly Ser Glu Pro Glu
                  65                  70                  75

 Glu Glu Glu Asp Val Ser Gln Ala Ile Leu Phe Pro Ala Thr Asp
                  80                  85                  90

 Ala Ser Cys Glu Asp Lys Ser Ala Ala Arg Gly Leu Ala Gln Glu
                  95                 100                 105

 Ala Glu Glu Gly Leu Phe Arg Tyr Met Phe Arg Pro Ser Gln His
                 110                 115                 120

 Thr Arg Ser Arg Gln Val Thr Ser Ala Gln Leu Trp Phe His Thr
                 125                 130                 135

 Gly Leu Asp Arg Gln Gly Thr Ala Ala Ser Asn Ser Ser Glu Pro
                 140                 145                 150

 Leu Leu Gly Leu Leu Ala Leu Ser Pro Gly Gly Pro Val Ala Val
                 155                 160                 165

 Pro Met Ser Leu Gly His Ala Pro Pro His Trp Ala Val Leu His
                 170                 175                 180

 Leu Ala Thr Ser Ala Leu Ser Leu Leu Thr His Pro Val Leu Val
                 185                 190                 195

 Leu Leu Leu Arg Cys Pro Leu Cys Thr Cys Ser Ala Arg Pro Glu
                 200                 205                 210

 Ala Thr Pro Phe Leu Val Ala His Thr Arg Thr Arg Pro Pro Ser
                 215                 220                 225

 Gly Gly Glu Arg Ala Arg Arg Ser Thr Pro Leu Met Ser Trp Pro
                 230                 235                 240

 Trp Ser Pro Ser Ala Leu Arg Leu Leu Gln Arg Pro Pro Glu Glu
                 245                 250                 255

 Pro Ala Ala His Ala Asn Cys His Arg Val Ala Leu Asn Ile Ser
                 260                 265                 270

 Phe Gln Glu Leu Gly Trp Glu Arg Trp Ile Val Tyr Pro Pro Ser
                 275                 280                 285

 Phe Ile Phe His Tyr Cys His Gly Gly Cys Gly Leu His Ile Pro
                 290                 295                 300

 Pro Asn Leu Ser Leu Pro Val Pro Gly Ala Pro Pro Thr Pro Ala
                 305                 310                 315

 Gln Pro Tyr Ser Leu Leu Pro Gly Ala Gln Pro Cys Cys Ala Ala
                 320                 325                 330

 Leu Pro Gly Thr Met Arg Pro Leu His Val Arg Thr Thr Ser Asp
                 335                 340                 345

 Gly Gly Tyr Ser Phe Lys Tyr Glu Thr Val Pro Asn Leu Leu Thr
                 350                 355                 360

 Gln His Cys Ala Cys Ile
                 365

<210> 2184
<211> 2875
<212> DNA
<213> Homo sapien

<400> 2184
 gaattctccg gagctgaaaa aggatcctga ctgaaagcta gaggcattga 50

 ggagcctgaa gattctcagg ttttaaagac gctagagtgc caaagaagac 100

 tttgaagtgt gaaaacattt cctgtaattg aaaccaaaat gtcatttata 150

 gatccttacc agcacattat agtggagcac cagtattccc acaagtttac 200

 ggtagtggtg ttacgtgcca ccaaagtgac aaagggggcc tttggtgaca 250

 tgcttgatac tccagatccc tatgtggaac tttttatctc tacaacccct 300

 gacagcagga agagaacaag acatttcaat aatgacataa accctgtgtg 350

 gaatgagacc tttgaattta ttttggatcc taatcaggaa aatgttttgg 400

 agattacgtt aatggatgcc aattatgtca tggatgaaac tctagggaca 450

 gcaacattta ctgtatcttc tatgaaggtg ggagaaaaga aagaagttcc 500

 ttttattttc aaccaagtca ctgaaatggt tctagaaatg tctcttgaag 550

 tttgctcatg cccagaccta cgatttagta tggctctgtg tgatcaggag 600

 aagactttca gacaacagag aaaagaacac ataagggaga gcatgaagaa 650

 actcttgggt ccaaagaata gtgaaggatt gcattctgca cgtgatgtgc 700

 ctgtggtagc catattgggt tcaggtgggg gtttccgagc catggtggga 750

 ttctctggtg tgatgaaggc attatacgaa tcaggaattc tggattgtgc 800

 tacctacgtt gctggtcttt ctggctccac ctggtatatg tcaaccttgt 850

 attctcaccc tgattttcca gagaaagggc cagaggagat taatgaagaa 900

 ctaatgaaaa atgttagcca caatcccctt ttacttctca caccacagaa 950

 agttaaaaga tatgttgagt ctttatggaa gaagaaaagc tctggacaac 1000

 ctgtcacctt tactgacatc tttgggatgt taataggaga aacactaatt 1050

 cataatagaa tgaatactac tctgagcagt ttgaaggaaa aagttaatac 1100

 tgcacaatgc cctttacctc ttttcacctg tcttcatgtc aaacctgacg 1150

 tttcagagct gatgtttgca gattgggttg aatttagtcc atacgaaatt 1200

 ggcatggcta aatatggtac ttttatggct cccgacttat ttggaagcaa 1250

 attttttatg ggaacagtcg ttaagaagta tgaagaaaac cccttgcatt 1300

 tcttaatggg tgtctggggc agtgcctttt ccatattgtt caacagagtt 1350

 ttgggcgttt ctggttcaca aagcagaggc tccacaatgg aggaagaatt 1400

 agaaaatatt accacaaagc atattgtgag taatgatagc tcggacagtg 1450

 atgatgaatc acacgaaccc aaaggcactg aaaatgaaga tgctggaagt 1500

 gactatcaaa gtgataatca agcaagttgg attcatcgta tgataatggc 1550

 cttggtgagt gattcagctt tattcaatac cagagaagga cgtgctggga 1600

 aggtacacaa cttcatgctg ggcttgaatc tcaatacatc ttatccactg 1650

 tctcctttga gtgactttgc cacacaggac tcctttgatg atgatgaact 1700

 ggatgcagct gtagcagatc ctgatgaatt tgagcgaata tatgagcctc 1750

 tggatgtcaa aagtaaaaag attcatgtag tggacagtgg gctcacattt 1800

 aacctgccgt atcccttgat actgagacct cagagagggg ttgatctcat 1850

 aatctccttt gacttttctg caaggccaag tgactctagt cctccgttca 1900

 aggaacttct acttgcagaa aagtgggcta aaatgaacaa gctccccttt 1950

 ccaaagattg atccttatgt gtttgatcgg gaagggctga aggagtgcta 2000

 tgtctttaaa cccaagaatc ctgatatgga gaaagattgc ccaaccatca 2050

 tccactttgt tctggccaac atcaacttca gaaagtacaa ggctccaggt 2100

 gttccaaggg aaactgagga agagaaagaa atcgctgact ttgatatttt 2150

 tgatgaccca gaatcaccat tttcaacctt caattttcaa tatccaaatc 2200

 aagcattcaa aagactacat gatcttatgc acttcaatac tctgaacaac 2250

 attgatgtga taaaagaagc catggttgaa agcattgaat atagaagaca 2300

 gaatccatct cgttgctctg tttcccttag taatgttgag gcaagaagat 2350

 ttttcaacaa ggagtttcta agtaaaccca aagcatagtt catgtactgg 2400

 aaatggcagc agtttctgat gctgaggcag tttgcaatcc catgacaact 2450

 ggatttaaaa gtacagtaca gatagtcgta ctgatcatga gagactggct 2500

 gatactcaaa gttgcagtta cttagctgca tgagaataat actattataa 2550

 gttaggtgac aaatgatgtt gattatgtaa ggatatactt agctacattt 2600

 tcagtcagta tgaacttcct gatacaaatg tagggatata tactgtattt 2650

 ttaaacattt ctcaccaact ttcttatgtg tgttcttttt aaaaattttt 2700

 tttcttttaa aatatttaac agttcaatct caataagacc tcgcattatg 2750

 tatgaatgtt attcactgac tagatttatt cataccatga gacaacacta 2800

 tttttattta tatatgcata tatatacata catgaaataa atacatcaat 2850

 ataaaaataa aaaaaaacgg aattc 2875

<210> 2185
<211> 749
<212> PRT
<213> Homo sapien

<400> 2185
 Met Ser Phe Ile Asp Pro Tyr Gln His Ile Ile Val Glu His Gln
   1               5                  10                  15

 Tyr Ser His Lys Phe Thr Val Val Val Leu Arg Ala Thr Lys Val
                  20                  25                  30

 Thr Lys Gly Ala Phe Gly Asp Met Leu Asp Thr Pro Asp Pro Tyr
                  35                  40                  45

 Val Glu Leu Phe Ile Ser Thr Thr Pro Asp Ser Arg Lys Arg Thr
                  50                  55                  60

 Arg His Phe Asn Asn Asp Ile Asn Pro Val Trp Asn Glu Thr Phe
                  65                  70                  75

 Glu Phe Ile Leu Asp Pro Asn Gln Glu Asn Val Leu Glu Ile Thr
                  80                  85                  90

 Leu Met Asp Ala Asn Tyr Val Met Asp Glu Thr Leu Gly Thr Ala
                  95                 100                 105

 Thr Phe Thr Val Ser Ser Met Lys Val Gly Glu Lys Lys Glu Val
                 110                 115                 120

 Pro Phe Ile Phe Asn Gln Val Thr Glu Met Val Leu Glu Met Ser
                 125                 130                 135

 Leu Glu Val Cys Ser Cys Pro Asp Leu Arg Phe Ser Met Ala Leu
                 140                 145                 150

 Cys Asp Gln Glu Lys Thr Phe Arg Gln Gln Arg Lys Glu His Ile
                 155                 160                 165

 Arg Glu Ser Met Lys Lys Leu Leu Gly Pro Lys Asn Ser Glu Gly
                 170                 175                 180

 Leu His Ser Ala Arg Asp Val Pro Val Val Ala Ile Leu Gly Ser
                 185                 190                 195

 Gly Gly Gly Phe Arg Ala Met Val Gly Phe Ser Gly Val Met Lys
                 200                 205                 210

 Ala Leu Tyr Glu Ser Gly Ile Leu Asp Cys Ala Thr Tyr Val Ala
                 215                 220                 225

 Gly Leu Ser Gly Ser Thr Trp Tyr Met Ser Thr Leu Tyr Ser His
                 230                 235                 240

 Pro Asp Phe Pro Glu Lys Gly Pro Glu Glu Ile Asn Glu Glu Leu
                 245                 250                 255

 Met Lys Asn Val Ser His Asn Pro Leu Leu Leu Leu Thr Pro Gln
                 260                 265                 270

 Lys Val Lys Arg Tyr Val Glu Ser Leu Trp Lys Lys Lys Ser Ser
                 275                 280                 285

 Gly Gln Pro Val Thr Phe Thr Asp Ile Phe Gly Met Leu Ile Gly
                 290                 295                 300

 Glu Thr Leu Ile His Asn Arg Met Asn Thr Thr Leu Ser Ser Leu
                 305                 310                 315

 Lys Glu Lys Val Asn Thr Ala Gln Cys Pro Leu Pro Leu Phe Thr
                 320                 325                 330

 Cys Leu His Val Lys Pro Asp Val Ser Glu Leu Met Phe Ala Asp
                 335                 340                 345

 Trp Val Glu Phe Ser Pro Tyr Glu Ile Gly Met Ala Lys Tyr Gly
                 350                 355                 360

 Thr Phe Met Ala Pro Asp Leu Phe Gly Ser Lys Phe Phe Met Gly
                 365                 370                 375

 Thr Val Val Lys Lys Tyr Glu Glu Asn Pro Leu His Phe Leu Met
                 380                 385                 390

 Gly Val Trp Gly Ser Ala Phe Ser Ile Leu Phe Asn Arg Val Leu
                 395                 400                 405

 Gly Val Ser Gly Ser Gln Ser Arg Gly Ser Thr Met Glu Glu Glu
                 410                 415                 420

 Leu Glu Asn Ile Thr Thr Lys His Ile Val Ser Asn Asp Ser Ser
                 425                 430                 435

 Asp Ser Asp Asp Glu Ser His Glu Pro Lys Gly Thr Glu Asn Glu
                 440                 445                 450

 Asp Ala Gly Ser Asp Tyr Gln Ser Asp Asn Gln Ala Ser Trp Ile
                 455                 460                 465

 His Arg Met Ile Met Ala Leu Val Ser Asp Ser Ala Leu Phe Asn
                 470                 475                 480

 Thr Arg Glu Gly Arg Ala Gly Lys Val His Asn Phe Met Leu Gly
                 485                 490                 495

 Leu Asn Leu Asn Thr Ser Tyr Pro Leu Ser Pro Leu Ser Asp Phe
                 500                 505                 510

 Ala Thr Gln Asp Ser Phe Asp Asp Asp Glu Leu Asp Ala Ala Val
                 515                 520                 525

 Ala Asp Pro Asp Glu Phe Glu Arg Ile Tyr Glu Pro Leu Asp Val
                 530                 535                 540

 Lys Ser Lys Lys Ile His Val Val Asp Ser Gly Leu Thr Phe Asn
                 545                 550                 555

 Leu Pro Tyr Pro Leu Ile Leu Arg Pro Gln Arg Gly Val Asp Leu
                 560                 565                 570

 Ile Ile Ser Phe Asp Phe Ser Ala Arg Pro Ser Asp Ser Ser Pro
                 575                 580                 585

 Pro Phe Lys Glu Leu Leu Leu Ala Glu Lys Trp Ala Lys Met Asn
                 590                 595                 600

 Lys Leu Pro Phe Pro Lys Ile Asp Pro Tyr Val Phe Asp Arg Glu
                 605                 610                 615

 Gly Leu Lys Glu Cys Tyr Val Phe Lys Pro Lys Asn Pro Asp Met
                 620                 625                 630

 Glu Lys Asp Cys Pro Thr Ile Ile His Phe Val Leu Ala Asn Ile
                 635                 640                 645

 Asn Phe Arg Lys Tyr Lys Ala Pro Gly Val Pro Arg Glu Thr Glu
                 650                 655                 660

 Glu Glu Lys Glu Ile Ala Asp Phe Asp Ile Phe Asp Asp Pro Glu
                 665                 670                 675

 Ser Pro Phe Ser Thr Phe Asn Phe Gln Tyr Pro Asn Gln Ala Phe
                 680                 685                 690

 Lys Arg Leu His Asp Leu Met His Phe Asn Thr Leu Asn Asn Ile
                 695                 700                 705

 Asp Val Ile Lys Glu Ala Met Val Glu Ser Ile Glu Tyr Arg Arg
                 710                 715                 720

 Gln Asn Pro Ser Arg Cys Ser Val Ser Leu Ser Asn Val Glu Ala
                 725                 730                 735

 Arg Arg Phe Phe Asn Lys Glu Phe Leu Ser Lys Pro Lys Ala
                 740                 745

<210> 2186
<211> 3140
<212> DNA
<213> Homo sapien

<400> 2186
 ggcgggcgct cggcgactcg tccccggggc cccgcgcggg cccgggcagc 50

 aggggcgtga tgtcacggca gggagggggc gcgggagccg ccgggccggc 100

 ggggaggcgg gggaggtgtt ttccagcttt aaaaaggcag gaggcagagc 150

 gcggccctgc gtcagagcga gactcagagg ctccgaactc gccggcggag 200

 tcgccgcgcc agatcccagc agcagggcgc gggcaccggg gcgcgggcag 250

 ggctcggagc caccgcgcag gtcctagggc cgcggccggg ccccgccacg 300

 cgcgcacacg cccctcgatg actttcctcc ggggcgcgcg gcgctgagcc 350

 cggggcgagg gctgtcttcc cggagacccg accccggcag cgcggggcgg 400

 ccgcttctcc tgtgcctccg cccgccgctc cactccccgc cgccgccgcg 450

 cggatgccaa gcaccagctt tccagtccct tccaagtttc cacttggccc 500

 tgcggctgcg gtcttcggga gaggagaaac tttggggccc gcgccgcgcg 550

 ccggcggcac catgaagtca gcggaggaag aacactatgg ctatgcatcc 600

 tccaacgtca gccccgccct gccgctcccc acggcgcact ccaccctgcc 650

 ggccccgtgc cacaaccttc agacctccac accgggcatc atcccgccgg 700

 cggatcaccc ctcggggtac ggagcagctt tggacggtgg gcccgcgggc 750

 tacttcctct cctccggcca caccaggcct gatggggccc ctgccctgga 800

 gagtcctcgc atcgagataa cctcgtgctt gggcctgtac cacaacaata 850

 accagttttt ccacgatgtg gaggtggaag acgtcctccc tagctccaaa 900

 cggtccccct ccacggccac gctgagtctg cccagcctgg aggcctacag 950

 agacccctcg tgcctgagcc cggccagcag cctgtcctcc cggagctgca 1000

 actcagaggc ctcctcctac gagtccaact actcgtaccc gtacgcgtcc 1050

 ccccagacgt cgccatggca gtctccctgc gtgtctccca agaccacgga 1100

 ccccgaggag ggctttcccc gcgggctggg ggcctgcaca ctgctgggtt 1150

 ccccgcggca ctccccctcc acctcgcccc gcgccagcgt cactgaggag 1200

 agctggctgg gtgcccgctc ctccagaccc gcgtcccctt gcaacaagag 1250

 gaagtacagc ctcaacggcc ggcagccgcc ctactcaccc caccactcgc 1300

 ccacgccgtc cccgcacggc tccccgcggg tcagcgtgac cgacgactcg 1350

 tggttgggca acaccaccca gtacaccagc tcggccatcg tggccgccat 1400

 caacgcgctg accaccgaca gcagcctgga cctgggagat ggcgtccctg 1450

 tcaagtcccg caagaccacc ctggagcagc cgccctcagt ggcgctcaag 1500

 gtggagcccg tcggggagga cctgggcagc cccccgcccc cggccgactt 1550

 cgcgcccgaa gactactcct ctttccagca catcaggaag ggcggcttct 1600

 gcgaccagta cctggcggtg ccgcagcacc cctaccagtg ggcgaagccc 1650

 aagcccctgt cccctacgtc ctacatgagc ccgaccctgc ccgccctgga 1700

 ctggcagctg ccgtcccact caggcccgta tgagcttcgg attgaggtgc 1750

 agcccaagtc ccaccaccga gcccactacg agacggaggg cagccggggg 1800

 gccgtgaagg cgtcggccgg aggacacccc atcgtgcagc tgcatggcta 1850

 cttggagaat gagccgctga tgctgcagct tttcattggg acggcggacg 1900

 accgcctgct gcgcccgcac gccttctacc aggtgcaccg catcacaggg 1950

 aagaccgtgt ccaccaccag ccacgaggcc atcctctcca acaccaaagt 2000

 cctggagatc ccactcctgc cggagaacag catgcgagcc gtcattgact 2050

 gtgccggaat cctgaaactc agaaactccg acattgaact tcggaaagga 2100

 gagacggaca tcgggaggaa gaacacacgg gtacggctgg tgttccgcgt 2150

 tcacgtcccg caacccagcg gccgcacgct gtccctgcag gtggcctcca 2200

 accccatcga atgctcccag cgctcagctc aggagctgcc tctggtggag 2250

 aagcagagca cggacagcta tccggtcgtg ggcgggaaga agatggtcct 2300

 gtctggccac aacttcctgc aggactccaa ggtcattttc gtggagaaag 2350

 ccccagatgg ccaccatgtc tgggagatgg aagcgaaaac tgaccgggac 2400

 ctgtgcaagc cgaattctct ggtggttgag atcccgccat ttcggaatca 2450

 gaggataacc agccccgttc acgtcagttt ctacgtctgc aacgggaaga 2500

 gaaagcgaag ccagtaccag cgtttcacct accttcccgc caacggtaac 2550

 gccatctttc taaccgtaag ccgtgaacat gagcgcgtgg ggtgcttttt 2600

 ctaaagacgc agaaacgacg tcgccgtaaa gcagcgtggc gtgttgcaca 2650

 tttaactgtg tgatgtcccg ttagtgagac cgagccatcg atgccctgaa 2700

 aaggaaagga aaagggaagc ttcggatgca ttttccttga tccctgttgg 2750

 gggtgggggg cgggggttgc atactcagat agtcacggtt attttgcttc 2800

 ttgcgaatgt ataacagcca aggggaaaac atggctcttc tgctccaaaa 2850

 aactgagggg gtcctggtgt gcatttgcac cctaaagctg cttacggtga 2900

 aaaggcaaat aggtatagct attttgcagg cacctttagg aataaacttt 2950

 gcttttaagc ctgtagtcct gatgtggtct ttaaggatgg tgaatgagct 3000

 ttgtgctggg cggacgtccc cgagacactt ctccaggggt aacttcatct 3050

 cctgggacca cgggcatcca ggctggggca ccttctcctc aacctgcctg 3100

 cccctcaccc gccgtgggaa tggctccttt tcactcatac 3140

<210> 2187
<211> 716
<212> PRT
<213> Homo sapien

<400> 2187
 Met Pro Ser Thr Ser Phe Pro Val Pro Ser Lys Phe Pro Leu Gly
   1               5                  10                  15

 Pro Ala Ala Ala Val Phe Gly Arg Gly Glu Thr Leu Gly Pro Ala
                  20                  25                  30

 Pro Arg Ala Gly Gly Thr Met Lys Ser Ala Glu Glu Glu His Tyr
                  35                  40                  45

 Gly Tyr Ala Ser Ser Asn Val Ser Pro Ala Leu Pro Leu Pro Thr
                  50                  55                  60

 Ala His Ser Thr Leu Pro Ala Pro Cys His Asn Leu Gln Thr Ser
                  65                  70                  75

 Thr Pro Gly Ile Ile Pro Pro Ala Asp His Pro Ser Gly Tyr Gly
                  80                  85                  90

 Ala Ala Leu Asp Gly Gly Pro Ala Gly Tyr Phe Leu Ser Ser Gly
                  95                 100                 105

 His Thr Arg Pro Asp Gly Ala Pro Ala Leu Glu Ser Pro Arg Ile
                 110                 115                 120

 Glu Ile Thr Ser Cys Leu Gly Leu Tyr His Asn Asn Asn Gln Phe
                 125                 130                 135

 Phe His Asp Val Glu Val Glu Asp Val Leu Pro Ser Ser Lys Arg
                 140                 145                 150

 Ser Pro Ser Thr Ala Thr Leu Ser Leu Pro Ser Leu Glu Ala Tyr
                 155                 160                 165

 Arg Asp Pro Ser Cys Leu Ser Pro Ala Ser Ser Leu Ser Ser Arg
                 170                 175                 180

 Ser Cys Asn Ser Glu Ala Ser Ser Tyr Glu Ser Asn Tyr Ser Tyr
                 185                 190                 195

 Pro Tyr Ala Ser Pro Gln Thr Ser Pro Trp Gln Ser Pro Cys Val
                 200                 205                 210

 Ser Pro Lys Thr Thr Asp Pro Glu Glu Gly Phe Pro Arg Gly Leu
                 215                 220                 225

 Gly Ala Cys Thr Leu Leu Gly Ser Pro Arg His Ser Pro Ser Thr
                 230                 235                 240

 Ser Pro Arg Ala Ser Val Thr Glu Glu Ser Trp Leu Gly Ala Arg
                 245                 250                 255

 Ser Ser Arg Pro Ala Ser Pro Cys Asn Lys Arg Lys Tyr Ser Leu
                 260                 265                 270

 Asn Gly Arg Gln Pro Pro Tyr Ser Pro His His Ser Pro Thr Pro
                 275                 280                 285

 Ser Pro His Gly Ser Pro Arg Val Ser Val Thr Asp Asp Ser Trp
                 290                 295                 300

 Leu Gly Asn Thr Thr Gln Tyr Thr Ser Ser Ala Ile Val Ala Ala
                 305                 310                 315

 Ile Asn Ala Leu Thr Thr Asp Ser Ser Leu Asp Leu Gly Asp Gly
                 320                 325                 330

 Val Pro Val Lys Ser Arg Lys Thr Thr Leu Glu Gln Pro Pro Ser
                 335                 340                 345

 Val Ala Leu Lys Val Glu Pro Val Gly Glu Asp Leu Gly Ser Pro
                 350                 355                 360

 Pro Pro Pro Ala Asp Phe Ala Pro Glu Asp Tyr Ser Ser Phe Gln
                 365                 370                 375

 His Ile Arg Lys Gly Gly Phe Cys Asp Gln Tyr Leu Ala Val Pro
                 380                 385                 390

 Gln His Pro Tyr Gln Trp Ala Lys Pro Lys Pro Leu Ser Pro Thr
                 395                 400                 405

 Ser Tyr Met Ser Pro Thr Leu Pro Ala Leu Asp Trp Gln Leu Pro
                 410                 415                 420

 Ser His Ser Gly Pro Tyr Glu Leu Arg Ile Glu Val Gln Pro Lys
                 425                 430                 435

 Ser His His Arg Ala His Tyr Glu Thr Glu Gly Ser Arg Gly Ala
                 440                 445                 450

 Val Lys Ala Ser Ala Gly Gly His Pro Ile Val Gln Leu His Gly
                 455                 460                 465

 Tyr Leu Glu Asn Glu Pro Leu Met Leu Gln Leu Phe Ile Gly Thr
                 470                 475                 480

 Ala Asp Asp Arg Leu Leu Arg Pro His Ala Phe Tyr Gln Val His
                 485                 490                 495

 Arg Ile Thr Gly Lys Thr Val Ser Thr Thr Ser His Glu Ala Ile
                 500                 505                 510

 Leu Ser Asn Thr Lys Val Leu Glu Ile Pro Leu Leu Pro Glu Asn
                 515                 520                 525

 Ser Met Arg Ala Val Ile Asp Cys Ala Gly Ile Leu Lys Leu Arg
                 530                 535                 540

 Asn Ser Asp Ile Glu Leu Arg Lys Gly Glu Thr Asp Ile Gly Arg
                 545                 550                 555

 Lys Asn Thr Arg Val Arg Leu Val Phe Arg Val His Val Pro Gln
                 560                 565                 570

 Pro Ser Gly Arg Thr Leu Ser Leu Gln Val Ala Ser Asn Pro Ile
                 575                 580                 585

 Glu Cys Ser Gln Arg Ser Ala Gln Glu Leu Pro Leu Val Glu Lys
                 590                 595                 600

 Gln Ser Thr Asp Ser Tyr Pro Val Val Gly Gly Lys Lys Met Val
                 605                 610                 615

 Leu Ser Gly His Asn Phe Leu Gln Asp Ser Lys Val Ile Phe Val
                 620                 625                 630

 Glu Lys Ala Pro Asp Gly His His Val Trp Glu Met Glu Ala Lys
                 635                 640                 645

 Thr Asp Arg Asp Leu Cys Lys Pro Asn Ser Leu Val Val Glu Ile
                 650                 655                 660

 Pro Pro Phe Arg Asn Gln Arg Ile Thr Ser Pro Val His Val Ser
                 665                 670                 675

 Phe Tyr Val Cys Asn Gly Lys Arg Lys Arg Ser Gln Tyr Gln Arg
                 680                 685                 690

 Phe Thr Tyr Leu Pro Ala Asn Gly Asn Ala Ile Phe Leu Thr Val
                 695                 700                 705

 Ser Arg Glu His Glu Arg Val Gly Cys Phe Phe
                 710                 715

<210> 2188
<211> 1493
<212> DNA
<213> Homo sapien

<400> 2188
 ttcctttcat gttcagcatt tctactcctt ccaagaagag cagcaaagct 50

 gaagtagcag caacagcacc agcagcaaca gcaaaaaaca aacatgagtg 100

 tgaagggcat ggctatagcc ttggctgtga tattgtgtgc tacagttgtt 150

 caaggcttcc ccatgttcaa aagaggacgc tgtctttgca taggccctgg 200

 ggtaaaagca gtgaaagtgg cagatattga gaaagcctcc ataatgtacc 250

 caagtaacaa ctgtgacaaa atagaagtga ttattaccct gaaagaaaat 300

 aaaggacaac gatgcctaaa tcccaaatcg aagcaagcaa ggcttataat 350

 caaaaaagtt gaaagaaaga atttttaaaa atatcaaaac atatgaagtc 400

 ctggaaaagg gcatctgaaa aacctagaac aagtttaact gtgactactg 450

 aaatgacaag aattctacag taggaaactg agacttttct atggttttgt 500

 gactttcaac ttttgtacag ttatgtgaag gatgaaaggt gggtgaaagg 550

 accaaaaaca gaaatacagt cttcctgaat gaatgacaat cagaattcca 600

 ctgcccaaag gagtccagca attaaatgga tttctaggaa aagctacctt 650

 aagaaaggct ggttaccatc ggagtttaca aagtgctttc acgttcttac 700

 ttgttgtatt atacattcat gcatttctag gctagagaac cttctagatt 750

 tgatgcttac aactattctg ttgtgactat gagaacattt ctgtctctag 800

 aagttatctg tctgtattga tctttatgct atattactat ctgtggttac 850

 agtggagaca ttgacattat tactggagtc aagcccttat aagtcaaaag 900

 catctatgtg tcgtaaagca ttcctcaaac attttttcat gcaaatacac 950

 acttctttcc ccaaatatca tgtagcacat caatatgtag ggaaacattc 1000

 ttatgcatca tttggtttgt tttataacca attcattaaa tgtaattcat 1050

 aaaatgtact atgaaaaaaa ttatacgcta tgggatactg gcaacagtgc 1100

 acatatttca taaccaaatt agcagcaccg gtcttaattt gatgtttttc 1150

 aacttttatt cattgagatg ttttgaagca attaggatat gtgtgtttac 1200

 tgtacttttt gttttgatcc gtttgtataa atgatagcaa tatcttggac 1250

 acatttgaaa tacaaaatgt ttttgtctac caaagaaaaa tgttgaaaaa 1300

 taagcaaatg tatacctagc aatcactttt actttttgta attctgtctc 1350

 ttagaaaaat acataatcta atcaatttct ttgttcatgc ctatatactg 1400

 taaaatttag gtatactcaa gactagttta aagaatcaaa gtcatttttt 1450

 tctctaataa actaccacaa cctttctttt ttaaaaaaaa aaa 1493

<210> 2189
<211> 94
<212> PRT
<213> Homo sapien

<400> 2189
 Met Ser Val Lys Gly Met Ala Ile Ala Leu Ala Val Ile Leu Cys
   1               5                  10                  15

 Ala Thr Val Val Gln Gly Phe Pro Met Phe Lys Arg Gly Arg Cys
                  20                  25                  30

 Leu Cys Ile Gly Pro Gly Val Lys Ala Val Lys Val Ala Asp Ile
                  35                  40                  45

 Glu Lys Ala Ser Ile Met Tyr Pro Ser Asn Asn Cys Asp Lys Ile
                  50                  55                  60

 Glu Val Ile Ile Thr Leu Lys Glu Asn Lys Gly Gln Arg Cys Leu
                  65                  70                  75

 Asn Pro Lys Ser Lys Gln Ala Arg Leu Ile Ile Lys Lys Val Glu
                  80                  85                  90

 Arg Lys Asn Phe


<210> 2190
<211> 960
<212> DNA
<213> Homo sapien

<400> 2190
 agcagctcca accagggcag ccttcctgag aagatgcaac caatcctgct 50

 tctgctggcc ttcctcctgc tgcccagggc agatgcaggg gagatcatcg 100

 ggggacatga ggccaagccc cactcccgcc cctacatggc ttatcttatg 150

 atctgggatc agaagtctct gaagaggtgc ggtggcttcc tgatacaaga 200

 cgacttcgtg ctgacagctg ctcactgttg gggaagctcc ataaatgtca 250

 ccttgggggc ccacaatatc aaagaacagg agccgaccca gcagtttatc 300

 cctgtgaaaa gacccatccc ccatccagcc tataatccta agaacttctc 350

 caacgacatc atgctactgc agctggagag aaaggccaag cggaccagag 400

 ctgtgcagcc cctcaggcta cctagcaaca aggcccaggt gaagccaggg 450

 cagacatgca gtgtggccgg ctgggggcag acggcccccc tgggaaaaca 500

 ctcacacaca ctacaagagg tgaagatgac agtgcaggaa gatcgaaagt 550

 gcgaatctga cttacgccat tattacgaca gtaccattga gttgtgcgtg 600

 ggggacccag agattaaaaa gacttccttt aagggggact ctggaggccc 650

 tcttgtgtgt aacaaggtgg cccagggcat tgtctcctat ggacgaaaca 700

 atggcatgcc tccacgagcc tgcaccaaag tctcaagctt tgtacactgg 750

 ataaagaaaa ccatgaaacg ctactaacta caggaagcaa actaagcccc 800

 cgctgtaatg aaacaccttc tctggagcca agtccagatt tacactggga 850

 gaggtgccag caactgaata aatacctctc ccagtgtaaa tctggagcca 900

 agtccagatt tacactggga gaggtgccag caactgaata aatacctctt 950

 agctgagtgg 960

<210> 2191
<211> 247
<212> PRT
<213> Homo sapien

<400> 2191
 Met Gln Pro Ile Leu Leu Leu Leu Ala Phe Leu Leu Leu Pro Arg
   1               5                  10                  15

 Ala Asp Ala Gly Glu Ile Ile Gly Gly His Glu Ala Lys Pro His
                  20                  25                  30

 Ser Arg Pro Tyr Met Ala Tyr Leu Met Ile Trp Asp Gln Lys Ser
                  35                  40                  45

 Leu Lys Arg Cys Gly Gly Phe Leu Ile Gln Asp Asp Phe Val Leu
                  50                  55                  60

 Thr Ala Ala His Cys Trp Gly Ser Ser Ile Asn Val Thr Leu Gly
                  65                  70                  75

 Ala His Asn Ile Lys Glu Gln Glu Pro Thr Gln Gln Phe Ile Pro
                  80                  85                  90

 Val Lys Arg Pro Ile Pro His Pro Ala Tyr Asn Pro Lys Asn Phe
                  95                 100                 105

 Ser Asn Asp Ile Met Leu Leu Gln Leu Glu Arg Lys Ala Lys Arg
                 110                 115                 120

 Thr Arg Ala Val Gln Pro Leu Arg Leu Pro Ser Asn Lys Ala Gln
                 125                 130                 135

 Val Lys Pro Gly Gln Thr Cys Ser Val Ala Gly Trp Gly Gln Thr
                 140                 145                 150

 Ala Pro Leu Gly Lys His Ser His Thr Leu Gln Glu Val Lys Met
                 155                 160                 165

 Thr Val Gln Glu Asp Arg Lys Cys Glu Ser Asp Leu Arg His Tyr
                 170                 175                 180

 Tyr Asp Ser Thr Ile Glu Leu Cys Val Gly Asp Pro Glu Ile Lys
                 185                 190                 195

 Lys Thr Ser Phe Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Asn
                 200                 205                 210

 Lys Val Ala Gln Gly Ile Val Ser Tyr Gly Arg Asn Asn Gly Met
                 215                 220                 225

 Pro Pro Arg Ala Cys Thr Lys Val Ser Ser Phe Val His Trp Ile
                 230                 235                 240

 Lys Lys Thr Met Lys Arg Tyr
                 245

<210> 2192
<211> 581
<212> DNA
<213> Homo sapien

<400> 2192
 gatacagtgc tccccactga aaattaaacc taaaaaatgt cacatattgg 50

 tatgttgtta acctggtaga ttaaatcatg agaatgatta gaaagacggg 100

 caacacagcg ggttacatcc acactgctga tcacaccaac gacaggagct 150

 gataagcaag aaagcgtcac agccagcgtc tgttcaccca aggttgacaa 200

 gtgaagtttc tctaatgttg attgttagcc gatttgtaac ctggcattta 250

 cttagcaact gccttatcaa ttacaggatt tgccggtaaa agcagactca 300

 aatataaagg tttttggctt aacttggttt attatagttg ctctatgttt 350

 gtaaacagac aatctctaat gtctgattat ttgtatcaca gatctgcagc 400

 tgccttggac ttgaatccat gcaatgttta gagtgtgaag tcagttactt 450

 gttgatgttt tcttactgta tcaatgaaat acatattgtc atgtcagttc 500

 ttgccaggaa cttctcaaca aaatggaatt ttttttttca gtatttcaat 550

 aaatattgat atgcccagcc tgataatttt t 581

<210> 2193
<211> 35
<212> PRT
<213> Homo sapien

<400> 2193
 Met Lys Tyr Ile Leu Ser Cys Gln Phe Leu Pro Gly Thr Ser Gln
   1               5                  10                  15

 Gln Asn Gly Ile Phe Phe Phe Ser Ile Ser Ile Asn Ile Asp Met
                  20                  25                  30

 Pro Ser Leu Ile Ile
                  35

<210> 2194
<211> 1280
<212> DNA
<213> Homo sapien

<400> 2194
 cgcggcggcg cggagctcgg gcggccgtgg aggaactcag cctcggccgc 50

 aggaggcgcc gggagcggag ccgccgggag tcgcgcaaca ggtttccttc 100

 tccatccgtg cgcccacagg ggacgcgcgc cctgccggga gaggggcttc 150

 tcggttcgca ctctcgctcc cagtccaggc aaaatgaaag accggctagc 200

 agaacttctg gacttgtcca agcaatatga ccagcagttc ccagacgggg 250

 acgatgagtt tgactcgccc cacgaggaca tcgtgttcga gacggaccac 300

 atcctggagt ccctgtaccg agacatccgg gacattcagg atgaaaacca 350

 gctgctggtg gccgacgtga agcggctggg aaagcagaac gcccgcttcc 400

 tcacgtccat gcggcgcctc agcagcatca agcgcgacac caactccatc 450

 gccaaggcct tcagggcccg gggcgaggtc atccactgca agctgcgcgc 500

 catgaaggag ctgagcgagg cggctgaggc ccagcacggc ccgcactcgg 550

 cagtggcgcg catttcgcgg gcgcagtaca acgcgctcac cctcaccttc 600

 cagcgcgcca tgcacgacta caaccaggcc gagatgaagc agcgcgacaa 650

 ctgcaagatc cgcatccagc gccagctgga gatcatgggc aaggaagtct 700

 cgggcgacca gatcgaggac atgttcgagc agggtaagtg ggacgtgttt 750

 tccgagaact tgctggccga cgtgaagggc cgcgggccgc ccacaacgag 800

 atcgagagcc gccaccgcga actgctgcgc ctggagagcc gccatccgcg 850

 acgtacacga gctcttcttg cagatggcgg tgctggtgga gaagcaggcc 900

 gacaccctga acgtcatcga gctcaacgta caaaagacgg tcgactacac 950

 cggccaggcc aaggcgcagg tgcggaaggc cgtgcagtac gaggagaaga 1000

 acccctgccg gaccctctgc tgcttctgct gtccctgcct caagtagcag 1050

 gccggcccgg gccgccaccg cccatcccag accatggagc gcgctgggaa 1100

 ggacgcacca aagccgggag ctctgccctg cagggagttg ccccaaccct 1150

 ttccggaact cagtctttag aaaagaaacg ccaggttcaa gaattgcaaa 1200

 ccagcctgtg cttggaaaga tggttagttg ataccgtccg atgattcttc 1250

 agtaaagata gattcccacc tcgtgccgaa 1280

<210> 2195
<211> 287
<212> PRT
<213> Homo sapien

<400> 2195
 Met Lys Asp Arg Leu Ala Glu Leu Leu Asp Leu Ser Lys Gln Tyr
   1               5                  10                  15

 Asp Gln Gln Phe Pro Asp Gly Asp Asp Glu Phe Asp Ser Pro His
                  20                  25                  30

 Glu Asp Ile Val Phe Glu Thr Asp His Ile Leu Glu Ser Leu Tyr
                  35                  40                  45

 Arg Asp Ile Arg Asp Ile Gln Asp Glu Asn Gln Leu Leu Val Ala
                  50                  55                  60

 Asp Val Lys Arg Leu Gly Lys Gln Asn Ala Arg Phe Leu Thr Ser
                  65                  70                  75

 Met Arg Arg Leu Ser Ser Ile Lys Arg Asp Thr Asn Ser Ile Ala
                  80                  85                  90

 Lys Ala Phe Arg Ala Arg Gly Glu Val Ile His Cys Lys Leu Arg
                  95                 100                 105

 Ala Met Lys Glu Leu Ser Glu Ala Ala Glu Ala Gln His Gly Pro
                 110                 115                 120

 His Ser Ala Val Ala Arg Ile Ser Arg Ala Gln Tyr Asn Ala Leu
                 125                 130                 135

 Thr Leu Thr Phe Gln Arg Ala Met His Asp Tyr Asn Gln Ala Glu
                 140                 145                 150

 Met Lys Gln Arg Asp Asn Cys Lys Ile Arg Ile Gln Arg Gln Leu
                 155                 160                 165

 Glu Ile Met Gly Lys Glu Val Ser Gly Asp Gln Ile Glu Asp Met
                 170                 175                 180

 Phe Glu Gln Gly Lys Trp Asp Val Phe Ser Glu Asn Leu Leu Ala
                 185                 190                 195

 Asp Val Lys Gly Arg Gly Pro Pro Thr Thr Arg Ser Arg Ala Ala
                 200                 205                 210

 Thr Ala Asn Cys Cys Ala Trp Arg Ala Ala Ile Arg Asp Val His
                 215                 220                 225

 Glu Leu Phe Leu Gln Met Ala Val Leu Val Glu Lys Gln Ala Asp
                 230                 235                 240

 Thr Leu Asn Val Ile Glu Leu Asn Val Gln Lys Thr Val Asp Tyr
                 245                 250                 255

 Thr Gly Gln Ala Lys Ala Gln Val Arg Lys Ala Val Gln Tyr Glu
                 260                 265                 270

 Glu Lys Asn Pro Cys Arg Thr Leu Cys Cys Phe Cys Cys Pro Cys
                 275                 280                 285

 Leu Lys


<210> 2196
<211> 2806
<212> DNA
<213> Homo sapien

<400> 2196
 gtgaaatccc attctctggc tggagacaca gatggcctca aatgagagag 50

 atgctatatc gtggtaccaa aagaagattg gagcctacga tcagcagata 100

 tgggaaaagt caatcgaaca gactcagatt aagggtttga aaaacaaacc 150

 gaaaaagatg ggccacataa agccagactt gattgacgtt gacttaatca 200

 gagggtcaac atttgccaaa gcaaaacctg aaattccatg gacatctctg 250

 actcggaagg ggcttgttcg agttgtattt tttccattgt tcagcaattg 300

 gtggattcag gttacctctt taagaatctt tgtttggctg ttactacttt 350

 atttcatgca agttatagca attgtcttat atttgatgat gcctattgtg 400

 aacataagtg aagtacttgg acccttgtgc cttatgctac tcatgggaac 450

 tgtccactgt caaattgtgt ctactcagat aacaagacca tcaggaaaca 500

 atggaaatcg aagaagaaga aaattacgaa aaactgtaaa tggtgatggg 550

 agccgagaaa atggaaataa ctcctctgat aaagtcagag gaatagaaac 600

 tttggaatct gtacccatta ttggtggttt ttgggagact atctttggca 650

 acaggattaa aagagtaaaa ttaatatcta acaaagggac tgaaactgac 700

 aatgacccaa gttgtgtcca tcctatcatt aagaggagac aatgtcgacc 750

 agagattaga atgtgccaaa caagagagaa accaaaattt tcagatggag 800

 aaaagtgccg tagggaggct tttaggcgtt tgggtaatgg ggtgtctgat 850

 gacctgtcaa gtgaagaaga tggtgaagca cggacacaga tgatattatt 900

 gcgtaggagt gtggaagggg cctcaagtga caatggttgt gaagttaaga 950

 atagaaaatc aatactttca aggcacctaa actctcaggt aaagaaaacc 1000

 actacaaggt ggtgtcatat tgtgcgggat tcagatagtc tggctgaatc 1050

 agaatttgaa tcagcagcct tcagccaggg ctctagatcg ggtgtgagtg 1100

 gtggctctcg aagcctcaac atgtcaagaa gagactcaga aagcacccgc 1150

 catgactcgg agactgagga catgttatgg gacgacctgc tacatggccc 1200

 agagtgccgg tcatctgtca ccagtgacag tgagggggcc catgtgaata 1250

 cccttcactc agggaccaaa cgtgacccca aagaggatgt ttttcagcag 1300

 aatcatttat tctggcttca gaattcaagt ccttcctctg atcgagttag 1350

 tgcaataatc tgggagggga atgagtgcaa aaagatggat atgtctgtgt 1400

 tggaaataag tggcatcatc atgagcaggg tcaatgccta tcagcaagga 1450

 gtaggttatc agatgctggg aaatgttgtc actattggat tagcattttt 1500

 tccattctta catcgacttt tccgtgagaa gagccttgac caactaaagt 1550

 ccatttcagc tgaggagatc ttgactctct ttggtggggc accacctgtt 1600

 acacctatta ttgtttggtc gataattaat ttttttgaaa gattgtgtct 1650

 tacttggatg ttttttttca tgatgtgtgt ggcagagaga acatataaac 1700

 agagattttt atttgcaaaa ctcttcagcc atattacttc tgccaggaaa 1750

 gctaggaaat atgaaatacc tcatttcaga cttaagaagg tggagaatat 1800

 taaaatatgg ttatcactgc gttcctatct aaagagacgg gggccacagc 1850

 gttcagttga tgtggttgta tcctcggttt tcctactgac actttcgatt 1900

 gctttcattt gttgtgctca ggttctccaa ggacataaaa cttccctgaa 1950

 tgatgcttat aactgggagt ttttgatctg ggaaacagct ttactacttt 2000

 ttttattgcg tctggcctca ctggggtctg aaaccaataa gaaatacagc 2050

 aatgtttcaa tattacttac agaacagatt aatttatatc ttaagatgga 2100

 aaaaaagcca aataagaaag aacagcttac tctagtaaac aatgtattaa 2150

 agctgtccac caagttgttg aaagagctgg acacaccatt tagactctat 2200

 ggactgacaa tgaatccctt aatctacaat atcacaagag tagttatcct 2250

 ttctgctgtc tcaggtgtta taagtgatct tctaggattt aatataagac 2300

 tgtggaaaat taaatcataa gctgagttaa atgcctggac tctcccctgg 2350

 ctggtatcaa aacttaccta tcaaggaaag tgatgactgc agaaaccagt 2400

 gagataccca cctgcttgtt cacatgcaca ggtgctctca gctctgcaaa 2450

 gcgaatgaat ggtgtttccg gaggagcaag tccttttcca actgggtgtg 2500

 catgctaaaa acctgtattt tcatgctttt caaacaacat gaatagtcag 2550

 ctgactaaag actgtgtgtg ttgtggtaac accaaagaca attttgatag 2600

 tttagcttca gtactgtgac agttatgttt actggacata gtctttttgg 2650

 caactatgat agatgcccaa agcatgaagc aaagctattt tatggaaata 2700

 tgcaaattca atacttttca ttatagtcta tagaactgga gatttcattt 2750

 ctctatcaaa gagagatcaa gcgaactatt taggtaaatc cgaataaaag 2800

 actttt 2806

<210> 2197
<211> 762
<212> PRT
<213> Homo sapien

<400> 2197
 Met Ala Ser Asn Glu Arg Asp Ala Ile Ser Trp Tyr Gln Lys Lys
   1               5                  10                  15

 Ile Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Ile Glu Gln
                  20                  25                  30

 Thr Gln Ile Lys Gly Leu Lys Asn Lys Pro Lys Lys Met Gly His
                  35                  40                  45

 Ile Lys Pro Asp Leu Ile Asp Val Asp Leu Ile Arg Gly Ser Thr
                  50                  55                  60

 Phe Ala Lys Ala Lys Pro Glu Ile Pro Trp Thr Ser Leu Thr Arg
                  65                  70                  75

 Lys Gly Leu Val Arg Val Val Phe Phe Pro Leu Phe Ser Asn Trp
                  80                  85                  90

 Trp Ile Gln Val Thr Ser Leu Arg Ile Phe Val Trp Leu Leu Leu
                  95                 100                 105

 Leu Tyr Phe Met Gln Val Ile Ala Ile Val Leu Tyr Leu Met Met
                 110                 115                 120

 Pro Ile Val Asn Ile Ser Glu Val Leu Gly Pro Leu Cys Leu Met
                 125                 130                 135

 Leu Leu Met Gly Thr Val His Cys Gln Ile Val Ser Thr Gln Ile
                 140                 145                 150

 Thr Arg Pro Ser Gly Asn Asn Gly Asn Arg Arg Arg Arg Lys Leu
                 155                 160                 165

 Arg Lys Thr Val Asn Gly Asp Gly Ser Arg Glu Asn Gly Asn Asn
                 170                 175                 180

 Ser Ser Asp Lys Val Arg Gly Ile Glu Thr Leu Glu Ser Val Pro
                 185                 190                 195

 Ile Ile Gly Gly Phe Trp Glu Thr Ile Phe Gly Asn Arg Ile Lys
                 200                 205                 210

 Arg Val Lys Leu Ile Ser Asn Lys Gly Thr Glu Thr Asp Asn Asp
                 215                 220                 225

 Pro Ser Cys Val His Pro Ile Ile Lys Arg Arg Gln Cys Arg Pro
                 230                 235                 240

 Glu Ile Arg Met Cys Gln Thr Arg Glu Lys Pro Lys Phe Ser Asp
                 245                 250                 255

 Gly Glu Lys Cys Arg Arg Glu Ala Phe Arg Arg Leu Gly Asn Gly
                 260                 265                 270

 Val Ser Asp Asp Leu Ser Ser Glu Glu Asp Gly Glu Ala Arg Thr
                 275                 280                 285

 Gln Met Ile Leu Leu Arg Arg Ser Val Glu Gly Ala Ser Ser Asp
                 290                 295                 300

 Asn Gly Cys Glu Val Lys Asn Arg Lys Ser Ile Leu Ser Arg His
                 305                 310                 315

 Leu Asn Ser Gln Val Lys Lys Thr Thr Thr Arg Trp Cys His Ile
                 320                 325                 330

 Val Arg Asp Ser Asp Ser Leu Ala Glu Ser Glu Phe Glu Ser Ala
                 335                 340                 345

 Ala Phe Ser Gln Gly Ser Arg Ser Gly Val Ser Gly Gly Ser Arg
                 350                 355                 360

 Ser Leu Asn Met Ser Arg Arg Asp Ser Glu Ser Thr Arg His Asp
                 365                 370                 375

 Ser Glu Thr Glu Asp Met Leu Trp Asp Asp Leu Leu His Gly Pro
                 380                 385                 390

 Glu Cys Arg Ser Ser Val Thr Ser Asp Ser Glu Gly Ala His Val
                 395                 400                 405

 Asn Thr Leu His Ser Gly Thr Lys Arg Asp Pro Lys Glu Asp Val
                 410                 415                 420

 Phe Gln Gln Asn His Leu Phe Trp Leu Gln Asn Ser Ser Pro Ser
                 425                 430                 435

 Ser Asp Arg Val Ser Ala Ile Ile Trp Glu Gly Asn Glu Cys Lys
                 440                 445                 450

 Lys Met Asp Met Ser Val Leu Glu Ile Ser Gly Ile Ile Met Ser
                 455                 460                 465

 Arg Val Asn Ala Tyr Gln Gln Gly Val Gly Tyr Gln Met Leu Gly
                 470                 475                 480

 Asn Val Val Thr Ile Gly Leu Ala Phe Phe Pro Phe Leu His Arg
                 485                 490                 495

 Leu Phe Arg Glu Lys Ser Leu Asp Gln Leu Lys Ser Ile Ser Ala
                 500                 505                 510

 Glu Glu Ile Leu Thr Leu Phe Gly Gly Ala Pro Pro Val Thr Pro
                 515                 520                 525

 Ile Ile Val Trp Ser Ile Ile Asn Phe Phe Glu Arg Leu Cys Leu
                 530                 535                 540

 Thr Trp Met Phe Phe Phe Met Met Cys Val Ala Glu Arg Thr Tyr
                 545                 550                 555

 Lys Gln Arg Phe Leu Phe Ala Lys Leu Phe Ser His Ile Thr Ser
                 560                 565                 570

 Ala Arg Lys Ala Arg Lys Tyr Glu Ile Pro His Phe Arg Leu Lys
                 575                 580                 585

 Lys Val Glu Asn Ile Lys Ile Trp Leu Ser Leu Arg Ser Tyr Leu
                 590                 595                 600

 Lys Arg Arg Gly Pro Gln Arg Ser Val Asp Val Val Val Ser Ser
                 605                 610                 615

 Val Phe Leu Leu Thr Leu Ser Ile Ala Phe Ile Cys Cys Ala Gln
                 620                 625                 630

 Val Leu Gln Gly His Lys Thr Ser Leu Asn Asp Ala Tyr Asn Trp
                 635                 640                 645

 Glu Phe Leu Ile Trp Glu Thr Ala Leu Leu Leu Phe Leu Leu Arg
                 650                 655                 660

 Leu Ala Ser Leu Gly Ser Glu Thr Asn Lys Lys Tyr Ser Asn Val
                 665                 670                 675

 Ser Ile Leu Leu Thr Glu Gln Ile Asn Leu Tyr Leu Lys Met Glu
                 680                 685                 690

 Lys Lys Pro Asn Lys Lys Glu Gln Leu Thr Leu Val Asn Asn Val
                 695                 700                 705

 Leu Lys Leu Ser Thr Lys Leu Leu Lys Glu Leu Asp Thr Pro Phe
                 710                 715                 720

 Arg Leu Tyr Gly Leu Thr Met Asn Pro Leu Ile Tyr Asn Ile Thr
                 725                 730                 735

 Arg Val Val Ile Leu Ser Ala Val Ser Gly Val Ile Ser Asp Leu
                 740                 745                 750

 Leu Gly Phe Asn Ile Arg Leu Trp Lys Ile Lys Ser
                 755                 760

<210> 2198
<211> 1672
<212> DNA
<213> Homo sapien

<400> 2198
 gatctctaga atagtcttaa gtctatgtgg cggcgaggcc gcggcgacaa 50

 ggtagccacc cccgcagcat gcctcgaccg cggtccgcag ctgcaccgcc 100

 tctccccgcc ccccagggtg cgctggtccc ggtcgcgcgc tcagacctcc 150

 gcatcccggg cgtggtcggt taagtccccg gccgtgaccc aggcccgggg 200

 agctagtctc cgcccttcgc tcttacggat cccctcggag tacgccgcac 250

 catgcagctc aggctcttcc ggcgcctcct tctcgccgct ttgctgctgg 300

 tgatcgtctg gaccctcttc gggccttcgg ggttggggga ggagctgctg 350

 agcctctcac tagcctccct gctcccagcc cccgcctcac cggggccgcc 400

 cctggccctg ccccgcctct tgatccccaa ccaggaagct tgcagtggtc 450

 ccggggcccc tcccttcctg ctcatcctgg tgtgcacggc tccggagaac 500

 ctgaaccaga gaaacgccat tcgggcttcg tggggcgggc tgcgcgaggc 550

 ccgggggctc agggtacaga cgctattctt gctgggagag ccgaacgcac 600

 agcaccccgt gtggggttcc caggggagtg acctggcctc ggagtcagca 650

 gcccaggggg atatcttgca ggccgccttc caggactcct accgcaacct 700

 caccctaaag accctcagcg ggctgaactg ggctgagaaa cactgcccca 750

 tggcccgata cgtcctcaag acggacgatg atgtgtatgt caacgtccct 800

 gaactggtat cagagctggt cttgcgaggg ggccgttggg ggcaatggga 850

 gagaagcacg gaaccccaga gagaggctga gcaggaagga ggccaggttt 900

 tgcacagcga ggaagtgcct cttctgtact tgggccgggt gcactggcgc 950

 gtgaacccct ctcggacacc ggggggcagg caccgcgtat cagaggagca 1000

 gtggcctcac acctggggcc cctttccacc ctatgcctca ggcacggggt 1050

 atgtgctgtc agcgtctgct gtgcagctca ttctcaaggt ggccagccgg 1100

 gcaccccttc tcccattaga ggatgtcttt gtgggggtaa gtgcccgacg 1150

 aggaggcctc gccccaacac agtgtgtcaa gctggctggt gccacccact 1200

 acccgctaga ccggtgctgc tatgggaaat tcctgctgac gtcccacagg 1250

 ctggacccct ggaagatgca ggaagcctgg aagctggtgg gtggctctga 1300

 cggggaaagg actgcgccct tttgctcctg gttccaggga gtcctgggca 1350

 tcctgcggtg tcgagcaata gcctggcttc agagctgaga gtgcctgggg 1400

 ccacaggaaa ggcaggaaca ggaccttctc tctcccaggc ccaacgcagg 1450

 ggccctcact ggctgcagct gatctgtttc cttataccag atcctcagtc 1500

 tcactaaaga cagcgatatg ggagacaccc aggggcctgg cccgccagcc 1550

 caaaagatgg tcatcgggaa gagaaaaaga aaaaaatgct gcagttgttc 1600

 tctcaagcta gggcagaaga gggtgtcaag ctcctcaata aacttgtctc 1650

 cacttaaaaa aaaaaaaaaa aa 1672

<210> 2199
<211> 378
<212> PRT
<213> Homo sapien

<400> 2199
 Met Gln Leu Arg Leu Phe Arg Arg Leu Leu Leu Ala Ala Leu Leu
   1               5                  10                  15

 Leu Val Ile Val Trp Thr Leu Phe Gly Pro Ser Gly Leu Gly Glu
                  20                  25                  30

 Glu Leu Leu Ser Leu Ser Leu Ala Ser Leu Leu Pro Ala Pro Ala
                  35                  40                  45

 Ser Pro Gly Pro Pro Leu Ala Leu Pro Arg Leu Leu Ile Pro Asn
                  50                  55                  60

 Gln Glu Ala Cys Ser Gly Pro Gly Ala Pro Pro Phe Leu Leu Ile
                  65                  70                  75

 Leu Val Cys Thr Ala Pro Glu Asn Leu Asn Gln Arg Asn Ala Ile
                  80                  85                  90

 Arg Ala Ser Trp Gly Gly Leu Arg Glu Ala Arg Gly Leu Arg Val
                  95                 100                 105

 Gln Thr Leu Phe Leu Leu Gly Glu Pro Asn Ala Gln His Pro Val
                 110                 115                 120

 Trp Gly Ser Gln Gly Ser Asp Leu Ala Ser Glu Ser Ala Ala Gln
                 125                 130                 135

 Gly Asp Ile Leu Gln Ala Ala Phe Gln Asp Ser Tyr Arg Asn Leu
                 140                 145                 150

 Thr Leu Lys Thr Leu Ser Gly Leu Asn Trp Ala Glu Lys His Cys
                 155                 160                 165

 Pro Met Ala Arg Tyr Val Leu Lys Thr Asp Asp Asp Val Tyr Val
                 170                 175                 180

 Asn Val Pro Glu Leu Val Ser Glu Leu Val Leu Arg Gly Gly Arg
                 185                 190                 195

 Trp Gly Gln Trp Glu Arg Ser Thr Glu Pro Gln Arg Glu Ala Glu
                 200                 205                 210

 Gln Glu Gly Gly Gln Val Leu His Ser Glu Glu Val Pro Leu Leu
                 215                 220                 225

 Tyr Leu Gly Arg Val His Trp Arg Val Asn Pro Ser Arg Thr Pro
                 230                 235                 240

 Gly Gly Arg His Arg Val Ser Glu Glu Gln Trp Pro His Thr Trp
                 245                 250                 255

 Gly Pro Phe Pro Pro Tyr Ala Ser Gly Thr Gly Tyr Val Leu Ser
                 260                 265                 270

 Ala Ser Ala Val Gln Leu Ile Leu Lys Val Ala Ser Arg Ala Pro
                 275                 280                 285

 Leu Leu Pro Leu Glu Asp Val Phe Val Gly Val Ser Ala Arg Arg
                 290                 295                 300

 Gly Gly Leu Ala Pro Thr Gln Cys Val Lys Leu Ala Gly Ala Thr
                 305                 310                 315

 His Tyr Pro Leu Asp Arg Cys Cys Tyr Gly Lys Phe Leu Leu Thr
                 320                 325                 330

 Ser His Arg Leu Asp Pro Trp Lys Met Gln Glu Ala Trp Lys Leu
                 335                 340                 345

 Val Gly Gly Ser Asp Gly Glu Arg Thr Ala Pro Phe Cys Ser Trp
                 350                 355                 360

 Phe Gln Gly Val Leu Gly Ile Leu Arg Cys Arg Ala Ile Ala Trp
                 365                 370                 375

 Leu Gln Ser


<210> 2200
<211> 781
<212> DNA
<213> Homo sapien

<400> 2200
 acacagagag aaaggctaaa gttctctgga ggatgtggct gcagagcctg 50

 ctgctcttgg gcactgtggc ctgcagcatc tctgcacccg cccgctcgcc 100

 cagccccagc acgcagccct gggagcatgt gaatgccatc caggaggccc 150

 ggcgtctcct gaacctgagt agagacactg ctgctgagat gaatgaaaca 200

 gtagaagtca tctcagaaat gtttgacctc caggagccga cctgcctaca 250

 gacccgcctg gagctgtaca agcagggcct gcggggcagc ctcaccaagc 300

 tcaagggccc cttgaccatg atggccagcc actacaagca gcactgccct 350

 ccaaccccgg aaacttcctg tgcaacccag attatcacct ttgaaagttt 400

 caaagagaac ctgaaggact ttctgcttgt catccccttt gactgctggg 450

 agccagtcca ggagtgagac cggccagatg aggctggcca agccggggag 500

 ctgctctctc atgaaacaag agctagaaac tcaggatggt catcttggag 550

 ggaccaaggg gtgggccaca gccatggtgg gagtggcctg gacctgccct 600

 gggccacact gaccctgata caggcatggc agaagaatgg gaatatttta 650

 tactgacaga aatcagtaat atttatatat ttatattttt aaaatattta 700

 tttatttatt tatttaagtt catattccat atttattcaa gatgttttac 750

 cgtaataatt attattaaaa atatgcttct a 781

<210> 2201
<211> 144
<212> PRT
<213> Homo sapien

<400> 2201
 Met Trp Leu Gln Ser Leu Leu Leu Leu Gly Thr Val Ala Cys Ser
   1               5                  10                  15

 Ile Ser Ala Pro Ala Arg Ser Pro Ser Pro Ser Thr Gln Pro Trp
                  20                  25                  30

 Glu His Val Asn Ala Ile Gln Glu Ala Arg Arg Leu Leu Asn Leu
                  35                  40                  45

 Ser Arg Asp Thr Ala Ala Glu Met Asn Glu Thr Val Glu Val Ile
                  50                  55                  60

 Ser Glu Met Phe Asp Leu Gln Glu Pro Thr Cys Leu Gln Thr Arg
                  65                  70                  75

 Leu Glu Leu Tyr Lys Gln Gly Leu Arg Gly Ser Leu Thr Lys Leu
                  80                  85                  90

 Lys Gly Pro Leu Thr Met Met Ala Ser His Tyr Lys Gln His Cys
                  95                 100                 105

 Pro Pro Thr Pro Glu Thr Ser Cys Ala Thr Gln Ile Ile Thr Phe
                 110                 115                 120

 Glu Ser Phe Lys Glu Asn Leu Lys Asp Phe Leu Leu Val Ile Pro
                 125                 130                 135

 Phe Asp Cys Trp Glu Pro Val Gln Glu
                 140

<210> 2202
<211> 2063
<212> DNA
<213> Homo sapien

<400> 2202
 tgccgggatc caggtctccg gggtccgctt tggccagagg cgcggaagga 50

 agcagtgccc ggcgacactg cacccatccc ggctgctttt gctgcgccct 100

 ctcagcttcc caagaaaggc atcgtcatgt gatcatcacc taagaactag 150

 aacatcagca ggccctagaa gcctcactct tgcccctccc tttaatatct 200

 caaaggatga cacttctgtg gtgtgtagtg agtctctact tttatggaat 250

 cctgcaaagt gatgcctcag aacgctgcga tgactgggga ctagacacca 300

 tgaggcaaat ccaagtgttt gaagatgagc cagctcgcat caagtgccca 350

 ctctttgaac acttcttgaa attcaactac agcacagccc attcagctgg 400

 ccttactctg atctggtatt ggactaggca ggaccgggac cttgaggagc 450

 caattaactt ccgcctcccc gagaaccgca ttagtaagga gaaagatgtg 500

 ctgtggttcc ggcccactct cctcaatgac actggcaact atacctgcat 550

 gttaaggaac actacatatt gcagcaaagt tgcatttccc ttggaagttg 600

 ttcaaaaaga cagctgtttc aattccccca tgaaactccc agtgcataaa 650

 ctgtatatag aatatggcat tcagaggatc acttgtccaa atgtagatgg 700

 atattttcct tccagtgtca aaccgactat cacttggtat atgggctgtt 750

 ataaaataca gaattttaat aatgtaatac ccgaaggtat gaacttgagt 800

 ttcctcattg ccttaatttc aaataatgga aattacacat gtgttgttac 850

 atatccagaa aatggacgta cgtttcatct caccaggact ctgactgtaa 900

 aggtagtagg ctctccaaaa aatgcagtgc cccctgtgat ccattcacct 950

 aatgatcatg tggtctatga gaaagaacca ggagaggagc tactcattcc 1000

 ctgtacggtc tattttagtt ttctgatgga ttctcgcaat gaggtttggt 1050

 ggaccattga tggaaaaaaa cctgatgaca tcactattga tgtcaccatt 1100

 aacgaaagta taagtcatag tagaacagaa gatgaaacaa gaactcagat 1150

 tttgagcatc aagaaagtta cctctgagga tctcaagcgc agctatgtct 1200

 gtcatgctag aagtgccaaa ggcgaagttg ccaaagcagc caaggtgaag 1250

 cagaaaggta atagatgcgg tcagtgatga atctctcagc tccaaattaa 1300

 cattgtggtg aataaggaca aaaggagaga ttgagaacaa gagagctcca 1350

 gcacctagcc cgacggcatc taacccatag taatgaatca aacttaaatg 1400

 aaaaatatga aagttttcat ctatgtaaga tactcaaaat attgtttctg 1450

 atattgttag taccgtaatg cccaaatgta gctaaaaaaa tcgacgtgag 1500

 tacagtgaga cacaattttg tgtctgtaca attatgaaaa attaaaaaca 1550

 aagaaaatat tcaaagctac caaagataga aaaaactggt agagccacat 1600

 attgttggtg aattattaag acccttttaa aaatcattca tggtagagtt 1650

 taagagtcat aaaaaagatt gcatcatctg acctaagact ttcggaattt 1700

 ttcctgaaca aataacagaa agggaattat atacctttta atattattag 1750

 aagcattatc tgtagttgta aaacattatt aatagcagcc atccaattgt 1800

 atgcaactaa ttaaggtatt gaatgtttat tttccaaaaa tgcataatta 1850

 taatattatt ttaaacacta tgtatcaata tttaagcagg tttataatat 1900

 accagcagcc acaattgcta aaatgaaaat catttaaatt atgattttaa 1950

 atggtataaa catgatttct atgttgatag tactatatta ttctacaata 2000

 aatggaaatt ataaagcctt cttgtcagaa gtgctgctcc taaaaaaaaa 2050

 aaaaaaaaaa aaa 2063

<210> 2203
<211> 356
<212> PRT
<213> Homo sapien

<400> 2203
 Met Thr Leu Leu Trp Cys Val Val Ser Leu Tyr Phe Tyr Gly Ile
   1               5                  10                  15

 Leu Gln Ser Asp Ala Ser Glu Arg Cys Asp Asp Trp Gly Leu Asp
                  20                  25                  30

 Thr Met Arg Gln Ile Gln Val Phe Glu Asp Glu Pro Ala Arg Ile
                  35                  40                  45

 Lys Cys Pro Leu Phe Glu His Phe Leu Lys Phe Asn Tyr Ser Thr
                  50                  55                  60

 Ala His Ser Ala Gly Leu Thr Leu Ile Trp Tyr Trp Thr Arg Gln
                  65                  70                  75

 Asp Arg Asp Leu Glu Glu Pro Ile Asn Phe Arg Leu Pro Glu Asn
                  80                  85                  90

 Arg Ile Ser Lys Glu Lys Asp Val Leu Trp Phe Arg Pro Thr Leu
                  95                 100                 105

 Leu Asn Asp Thr Gly Asn Tyr Thr Cys Met Leu Arg Asn Thr Thr
                 110                 115                 120

 Tyr Cys Ser Lys Val Ala Phe Pro Leu Glu Val Val Gln Lys Asp
                 125                 130                 135

 Ser Cys Phe Asn Ser Pro Met Lys Leu Pro Val His Lys Leu Tyr
                 140                 145                 150

 Ile Glu Tyr Gly Ile Gln Arg Ile Thr Cys Pro Asn Val Asp Gly
                 155                 160                 165

 Tyr Phe Pro Ser Ser Val Lys Pro Thr Ile Thr Trp Tyr Met Gly
                 170                 175                 180

 Cys Tyr Lys Ile Gln Asn Phe Asn Asn Val Ile Pro Glu Gly Met
                 185                 190                 195

 Asn Leu Ser Phe Leu Ile Ala Leu Ile Ser Asn Asn Gly Asn Tyr
                 200                 205                 210

 Thr Cys Val Val Thr Tyr Pro Glu Asn Gly Arg Thr Phe His Leu
                 215                 220                 225

 Thr Arg Thr Leu Thr Val Lys Val Val Gly Ser Pro Lys Asn Ala
                 230                 235                 240

 Val Pro Pro Val Ile His Ser Pro Asn Asp His Val Val Tyr Glu
                 245                 250                 255

 Lys Glu Pro Gly Glu Glu Leu Leu Ile Pro Cys Thr Val Tyr Phe
                 260                 265                 270

 Ser Phe Leu Met Asp Ser Arg Asn Glu Val Trp Trp Thr Ile Asp
                 275                 280                 285

 Gly Lys Lys Pro Asp Asp Ile Thr Ile Asp Val Thr Ile Asn Glu
                 290                 295                 300

 Ser Ile Ser His Ser Arg Thr Glu Asp Glu Thr Arg Thr Gln Ile
                 305                 310                 315

 Leu Ser Ile Lys Lys Val Thr Ser Glu Asp Leu Lys Arg Ser Tyr
                 320                 325                 330

 Val Cys His Ala Arg Ser Ala Lys Gly Glu Val Ala Lys Ala Ala
                 335                 340                 345

 Lys Val Lys Gln Lys Gly Asn Arg Cys Gly Gln
                 350                 355

<210> 2204
<211> 1242
<212> DNA
<213> Homo sapien

<400> 2204
 agttacgttc ggggcgtggc cgggagcacg ttggctccgc cccctggcgg 50

 ctgcctcagc ggcggcggcg gcgcaggctc agagcagacc ccgcccggcg 100

 aggaggaggg agggccgcca gtgtcgacat gctgctggag gaggttcgcg 150

 ccggcgaccg gctgagtggg gcggcggccc ggggcgacgt gcaggaggtg 200

 cgccgccttc tgcaccgcga gctggtgcat cccgacgccc tcaaccgctt 250

 cggcaagacg gcgctgcagg tcatgatgtt tggcagcacc gccatcgccc 300

 tggagctgct gaagcaaggt gccagcccca atgtccagga cacctccggt 350

 accagtccag tccatgacgc agcccgcact ggattcctgg acaccctgaa 400

 ggtcctagtg gagcacgggg ctgatgtcaa cgtgcctgat ggcaccgggg 450

 cacttccaat ccatctggca gttcaagagg gtcacactgc tgtggtcagc 500

 tttctggcag ctgaatctga tctccatcgc agggacgcca ggggtctcac 550

 acccttggag ctggcactgc agagaggggc tcaggacctc gtggacatcc 600

 tgcagggcca catggtggcc ccgctgtgat ctggggtcac cctctccagc 650

 aagagaaccc cgtggggtta tgtatcagaa gagaggggaa gaaacacttt 700

 ctcttcttgt ttctcctgcc cactgctgca gtaggggagg agcacagttt 750

 gtggcttata ggtgttggtt ttgggggtgt gagtgtttgg gggacgtttc 800

 tcatttgttt ttctcactcc ttttggtgtg ttggacagag aagggctcct 850

 gcaggccaca gccacctaaa cggttcagtt tcttctgcgc ctcaggctgc 900

 tggggcctca gacgagaccc aagggcagag catttaagag tgaagtcatg 950

 acctccaggg agcctagaag ctggtggcct tggccggctg tgctcagaga 1000

 cctgaagtgt gcacgttgct tcaggcatgg ggggtggggg gagcgtccca 1050

 aatcaataag aaggtagaat gagttatgag ttattcatat tctgttggaa 1100

 gcttgttttc cagtctcttg tacagcgttt taaaagaaat ggattctatt 1150

 tattatgctt tattggaaaa aatgttgtaa taatttaatg tttttaccca 1200

 ttaaattaag acttgtgcat gatcaaaaaa aaaaaaaaaa aa 1242

<210> 2205
<211> 166
<212> PRT
<213> Homo sapien

<400> 2205
 Met Leu Leu Glu Glu Val Arg Ala Gly Asp Arg Leu Ser Gly Ala
   1               5                  10                  15

 Ala Ala Arg Gly Asp Val Gln Glu Val Arg Arg Leu Leu His Arg
                  20                  25                  30

 Glu Leu Val His Pro Asp Ala Leu Asn Arg Phe Gly Lys Thr Ala
                  35                  40                  45

 Leu Gln Val Met Met Phe Gly Ser Thr Ala Ile Ala Leu Glu Leu
                  50                  55                  60

 Leu Lys Gln Gly Ala Ser Pro Asn Val Gln Asp Thr Ser Gly Thr
                  65                  70                  75

 Ser Pro Val His Asp Ala Ala Arg Thr Gly Phe Leu Asp Thr Leu
                  80                  85                  90

 Lys Val Leu Val Glu His Gly Ala Asp Val Asn Val Pro Asp Gly
                  95                 100                 105

 Thr Gly Ala Leu Pro Ile His Leu Ala Val Gln Glu Gly His Thr
                 110                 115                 120

 Ala Val Val Ser Phe Leu Ala Ala Glu Ser Asp Leu His Arg Arg
                 125                 130                 135

 Asp Ala Arg Gly Leu Thr Pro Leu Glu Leu Ala Leu Gln Arg Gly
                 140                 145                 150

 Ala Gln Asp Leu Val Asp Ile Leu Gln Gly His Met Val Ala Pro
                 155                 160                 165

 Leu


<210> 2206
<211> 1409
<212> DNA
<213> Homo sapien

<400> 2206
 gaaagagaca aagcagcaat taaagtcagc ccagcaccaa ctccgacgcc 50

 aagcgttaca ctggaaacta ctttttaaag caacaaaaga gtctaaaaca 100

 aaatacaaca tttcttaaat acactgtttc cagaaagagc tattttaaca 150

 gaagcaactc aaagatatcc cttcgacaga agtggaagtg ctgaaaaatg 200

 ctcatctctc acacagactt ttgatggaca ggagtttcta agtatcatgc 250

 ctaccaacaa gctgtaaaat gatcaccctg aacaatcaag atcaacctgt 300

 cccttttaac agctcacatc cagatgaata caaaattgca gcccttgtct 350

 tctatagctg tatcttcata attggattat ttgttaacat cactgcatta 400

 tgggttttca gttgtaccac caagaagaga accacggtaa ccatctatat 450

 gatgaatgtg gcattagtgg acttgatatt tataatgact ttaccctttc 500

 gaatgtttta ttatgcaaaa gatgaatggc catttggaga gtacttctgc 550

 cagattcttg gagctctcac agtgttttac ccaagcattg ctttatggct 600

 tcttgccttt attagtgctg acagatacat ggccattgta cagccgaagt 650

 acgccaaaga acttaaaaac acgtgcaaag ccgtgctggc gtgtgtggga 700

 gtctggataa tgaccctgac cacgaccacc cctctgctac tgctctataa 750

 agacccagat aaagactcca ctcccgccac ctgcctcaag atttctgaca 800

 tcatctatct aaaagctgtg aacgtgctga acctcactcg actgacattt 850

 tttttcttga ttcctttgtt catcatgatt gggtgctact tggtcattat 900

 tcataatctc cttcacggca ggacgtctaa gctgaaaccc aaagtcaagg 950

 agaagtccat aaggatcatc atcacgctgc tggtgcaggt gctcgtctgc 1000

 tttatgccct tccacatctg tttcgctttc ctgatgctgg gaacggggga 1050

 gaacagttac aatccctggg gagcctttac caccttcctc atgaacctca 1100

 gcacgtgtct ggatgtgatt ctctactaca tcgtttcaaa acaatttcag 1150

 gctcgagtca ttagtgtcat gctataccgt aattaccttc gaagcatgcg 1200

 cagaaaaagt ttccgatctg gtagtctacg gtcactaagc aatataaaca 1250

 gtgaaatgtt atgaataata aggttctttc atttcaatcc catcaaaatt 1300

 cacttcacta actactctgg cgtcaatgga tattctgtat aatactatca 1350

 agtccctttt ctcttgaaaa aataaattca ttatcttcat tttaaaaaaa 1400

 aaaaaaaaa 1409

<210> 2207
<211> 331
<212> PRT
<213> Homo sapien

<400> 2207
 Met Ile Thr Leu Asn Asn Gln Asp Gln Pro Val Pro Phe Asn Ser
   1               5                  10                  15

 Ser His Pro Asp Glu Tyr Lys Ile Ala Ala Leu Val Phe Tyr Ser
                  20                  25                  30

 Cys Ile Phe Ile Ile Gly Leu Phe Val Asn Ile Thr Ala Leu Trp
                  35                  40                  45

 Val Phe Ser Cys Thr Thr Lys Lys Arg Thr Thr Val Thr Ile Tyr
                  50                  55                  60

 Met Met Asn Val Ala Leu Val Asp Leu Ile Phe Ile Met Thr Leu
                  65                  70                  75

 Pro Phe Arg Met Phe Tyr Tyr Ala Lys Asp Glu Trp Pro Phe Gly
                  80                  85                  90

 Glu Tyr Phe Cys Gln Ile Leu Gly Ala Leu Thr Val Phe Tyr Pro
                  95                 100                 105

 Ser Ile Ala Leu Trp Leu Leu Ala Phe Ile Ser Ala Asp Arg Tyr
                 110                 115                 120

 Met Ala Ile Val Gln Pro Lys Tyr Ala Lys Glu Leu Lys Asn Thr
                 125                 130                 135

 Cys Lys Ala Val Leu Ala Cys Val Gly Val Trp Ile Met Thr Leu
                 140                 145                 150

 Thr Thr Thr Thr Pro Leu Leu Leu Leu Tyr Lys Asp Pro Asp Lys
                 155                 160                 165

 Asp Ser Thr Pro Ala Thr Cys Leu Lys Ile Ser Asp Ile Ile Tyr
                 170                 175                 180

 Leu Lys Ala Val Asn Val Leu Asn Leu Thr Arg Leu Thr Phe Phe
                 185                 190                 195

 Phe Leu Ile Pro Leu Phe Ile Met Ile Gly Cys Tyr Leu Val Ile
                 200                 205                 210

 Ile His Asn Leu Leu His Gly Arg Thr Ser Lys Leu Lys Pro Lys
                 215                 220                 225

 Val Lys Glu Lys Ser Ile Arg Ile Ile Ile Thr Leu Leu Val Gln
                 230                 235                 240

 Val Leu Val Cys Phe Met Pro Phe His Ile Cys Phe Ala Phe Leu
                 245                 250                 255

 Met Leu Gly Thr Gly Glu Asn Ser Tyr Asn Pro Trp Gly Ala Phe
                 260                 265                 270

 Thr Thr Phe Leu Met Asn Leu Ser Thr Cys Leu Asp Val Ile Leu
                 275                 280                 285

 Tyr Tyr Ile Val Ser Lys Gln Phe Gln Ala Arg Val Ile Ser Val
                 290                 295                 300

 Met Leu Tyr Arg Asn Tyr Leu Arg Ser Met Arg Arg Lys Ser Phe
                 305                 310                 315

 Arg Ser Gly Ser Leu Arg Ser Leu Ser Asn Ile Asn Ser Glu Met
                 320                 325                 330

 Leu


<210> 2208
<211> 5050
<212> DNA
<213> Homo sapien

<400> 2208
 cgaagggggg tgggccgggg gaggggaggt tcgttccgcg gagcgcagcc 50

 agaaccggga ccaagaatcg ccttcagccc tgtctggtgc atccttggca 100

 gaaagtgagg aggaaaacac ccccattgtt agatgaggtc ttaatcatgg 150

 aacatttgaa gtcacgtaaa gaaggttctt tggcatggac acaagttcag 200

 tgggaggatt agaattgact gatcagactc ctgttttatt agggagtacg 250

 gccatggcaa ctagtctcac gaatgtagga aactcattta gtggtccagc 300

 taatccttta gtgtctagat ctaataagtt tcagaactcg tcagtggaag 350

 atgatgatga tgttgttttt atcgaacctg tacaacctcc cccaccttct 400

 gtaccagtgg tagctgatca aagaaccata acatttacat catcaaaaaa 450

 tgaagaacta caaggaaatg attccaaaat tactccttcc tcaaaagagt 500

 tggcatctca gaagggaagt gtaagtgaga caattgtcat tgatgatgaa 550

 gaggacatgg aaacaaatca agggcaagag aaaaattcct ccaattttat 600

 tgaacgaaga cctcctgaga ctaaaaacag aaccaatgat gtggatttct 650

 ccacttccag tttttcaaga agtaaggtaa atgcaggaat gggtaatagt 700

 ggtatcacca cagaaccaga ctctgaaatt cagattgcta atgttacaac 750

 tttagaaaca ggtgtaagct ctgtgaatga tggccaatta gaaaatactg 800

 acgggcgaga tatgaactta atgattacac atgtaacatc actgcagaat 850

 accaacttgg gagatgtctc taacggactg cagtcaagta attttggtgt 900

 taatatacaa acatacaccc catctttaac ttcacagacc aagactggag 950

 taggaccttt taatcctggt agaatgaatg tggcaggaga cgtttttcag 1000

 aatggagaat ctgcaactca tcataatcct gattcttgga tctcccagtc 1050

 agcttcattt ccccgtaatc agaaacaacc aggggtggac tctttatcac 1100

 cagtggcctc acttcctaaa cagattttcc agccgtctgt ccaacagcag 1150

 cctactaaac cagttaaagt cacttgtgca aactgcaaaa aacctttaca 1200

 gaagggccag acagcttatc aacgaaaagg atcagctcac ctcttttgtt 1250

 ctaccacctg cctttcttcc ttctcccaca agcctgctcc aaagaaactc 1300

 tgtgttatgt gtaaaaaaga tataactaca atgaaaggaa ccattgttgc 1350

 tcaagtggat tcaagtgagt ccttccagga attctgtagt acatcttgtt 1400

 tatctctcta tgaagacaaa cagaatccta ctaaaggagc tctaaataaa 1450

 tcaagatgta caatctgtgg taaactaact gagattcgcc atgaagtcag 1500

 ctttaaaaat atgactcata agctgtgcag tgaccactgc tttaatagat 1550

 atagaatggc caatggttta ataatgaatt gctgtgaaca gtgtggagag 1600

 tacttgccca gtaaaggtgc tggaaataat gttctggtga ttgatggtca 1650

 acagaaaaga ttttgctgtc aaagttgtgt cagtgaatac aaacaggtag 1700

 gtagccatcc aagcttcctg aaggaggttc gagatcacat gcaggactct 1750

 ttcttaatgc agcctgagaa atatggaaaa ctgacaactt gtactggttg 1800

 ccgaacacag tgcaggtttt ttgatatgac tcagtgtata ggtcctaatg 1850

 gatatatgga gccatattgt tcaactgctt gtatgaacag tcacaagaca 1900

 aaatatgcaa aatcacaaag tttgggaatt atttgccatt tttgtaagcg 1950

 aaactcttta cctcaatacc aagccacaat gcctgatgga aaactgtaca 2000

 acttttgcaa ttccagttgt gtggctaaat ttcaggctct aagtatgcag 2050

 tcatctccaa atggccagtt tgtagcgcca agtgatattc agttgaaatg 2100

 caactactgc aaaaattcct tttgttcaaa accagaaatc ctggaatggg 2150

 agaacaaagt gcatcagttc tgcagcaaaa cttgttcaga tgactataag 2200

 aagttgcatt gcatagttac atattgcgaa tactgtcaag aggagaagac 2250

 tcttcatgaa acagtaaatt tctctggcgt taagagacct ttctgtagtg 2300

 aaggctgcaa attattatac aaacaggatt ttgccagacg tttaggattg 2350

 agatgtgtta cttgcaacta ttgttctcag ctatgtaaga agggagcaac 2400

 taaagaactc gatggtgttg tgagagattt ctgcagtgaa gattgctgta 2450

 aaaaatttca ggattggtac tacaaggctg caaggtgtga ctgttgtaaa 2500

 tctcaaggaa ctcttaaaga gcgagttcag tggcgtgggg aaatgaaaca 2550

 tttctgtgat caacattgct tactgcgttt ctactgtcaa caaaatgagc 2600

 ccaacatgac aactcagaaa ggacctgaaa acttacatta tgatcagggt 2650

 tgtcagacat ctcgaaccaa aatgacaggt tcagcaccac ccccttctcc 2700

 aacacctaac aaagagatga agaacaaagc agttctttgc aaacctttaa 2750

 caatgacaaa agctacttac tgtaaacctc acatgcagac caaatcttgt 2800

 cagacagatg atacttggag gacagaatat gttccagtgc ctatccctgt 2850

 gcctgtgtat atcccagttc ctatgcacat gtacagtcag aatattcctg 2900

 ttcctactac agttcctgtt cctgtgccag ttcctgtttt tctgcctgct 2950

 ccattggaca gcagtgagaa gattcctgca gcaattgagg agctaaaaag 3000

 caaggtttct tcagatgctc ttgatacaga gttgcttaca atgacggata 3050

 tgatgagtga agacgagggg aaaacagaga caaccaacat caacagtgta 3100

 attattgaaa cagatataat tggttcagac cttttgaaga actctgaccc 3150

 agagacacag tccagcatgc ctgatgtacc atatgaacca gatttggata 3200

 tcgaaataga ttttcccaga gctgctgagg agcttgatat ggaaaatgaa 3250

 tttttattac cacctgtttt tggcgaagaa tatgaggaac agcccagacc 3300

 tcgatctaaa aaaaagggag ccaagagaaa ggctgtatca ggataccagt 3350

 ctcatgatga tagttctgac aattcagaat gcagctttcc tttcaaatat 3400

 acgtatggcg taaatgcatg gaaacactgg gtcaaaacta ggcaacttga 3450

 tgaagatctt ctggtattag atgagttaaa atcttctaaa tcagtaaagt 3500

 taaaagagga tctactctct cacaccacag ctgagcttaa ctatgggtta 3550

 gctcattttg tcaatgagat ccgacggcca aatggagaga attatgcacc 3600

 tgacagcatc tattaccttt gccttggaat acaggagtat ttgtgtggaa 3650

 gtaatcgaaa agacaacata tttattgatc ctggatacca aacatttgag 3700

 caagaattga ataaaatact gcgaagctgg caaccaagca tacttccaga 3750

 tgggtcaata ttctctcgag ttgaagaaga ctatctctgg aggataaaac 3800

 aactaggatc acactctcca gtagctcttc tgaatacact gttctacttt 3850

 aacactaagt attttggcct gaaaacagtg gaacaacact taagactttc 3900

 ctttggcact gtgtttaggc attggaaaaa aaatccttta acgatggaaa 3950

 acaaagcgtg tcttcgatac caagtgtctt ccttgtgtgg aacagataat 4000

 gaagataaaa ttactactgg aaaaagaaaa catgaagatg atgagccagt 4050

 atttgaacaa attgaaaaca cagccaatcc ttccagatgt cctgtgaaaa 4100

 tgtttgaatg ctacttgtct aaaagtccac agaatcttaa tcagaggatg 4150

 gatgtttttt atttgcaacc agaatgctct agttctacag atagccctgt 4200

 ctggtatacg tctacttcac tggaccgaaa caccttggaa aatatgcttg 4250

 tacgggttct tctagtaaaa gatatttatg ataaagacaa ttatgaactg 4300

 gatgaagaca cagactaaaa aggaacgttg cagaagcaat cgggataaaa 4350

 cagcattaga tagtcatgct gctagatctt tattatggaa aacatttcaa 4400

 gtttactcct tctgttttga gttttgtagc agtgtaccca cgctgggtat 4450

 taccatgtaa ataatctgtg agtgaaagtt gccattattc tatgtagtgg 4500

 ttttaggata cttaacaaat acattcaaat tcttttttta ttattattta 4550

 tttgattagg tatgtttgta actttttaca ttacagaata tgaatgagaa 4600

 tgtgccatgt ataatttttt tcttgtagta agaaacatcc atattgcaca 4650

 actctactgt tgcaaagctt ccttggaagg gggctctttt actgggttct 4700

 taaccagatg gttgtgtatg ggtagcacta ctaaaagttt agaacttgca 4750

 gtgtctttcg gaatttttaa aataaactgt aaactaatag gctggggttt 4800

 ttgttttgtt ttggggtttt gttttgtttg gttttacatt ttagttactg 4850

 aagccttaca aggttatgta gagagatacc atcttctgta ccaaaaatag 4900

 acaagagaat gctgtcaata ttggtgtact gtaatgtgaa tctatgctgg 4950

 tgaaaacaat tttttgttcc ccttattaaa accttagtgt ccttttctca 5000

 tttgtggctt tctgcatcac ccaatcaata aaaaacaaat atatatatgt 5050

<210> 2209
<211> 1377
<212> PRT
<213> Homo sapien

<400> 2209
 Met Asp Thr Ser Ser Val Gly Gly Leu Glu Leu Thr Asp Gln Thr
   1               5                  10                  15

 Pro Val Leu Leu Gly Ser Thr Ala Met Ala Thr Ser Leu Thr Asn
                  20                  25                  30

 Val Gly Asn Ser Phe Ser Gly Pro Ala Asn Pro Leu Val Ser Arg
                  35                  40                  45

 Ser Asn Lys Phe Gln Asn Ser Ser Val Glu Asp Asp Asp Asp Val
                  50                  55                  60

 Val Phe Ile Glu Pro Val Gln Pro Pro Pro Pro Ser Val Pro Val
                  65                  70                  75

 Val Ala Asp Gln Arg Thr Ile Thr Phe Thr Ser Ser Lys Asn Glu
                  80                  85                  90

 Glu Leu Gln Gly Asn Asp Ser Lys Ile Thr Pro Ser Ser Lys Glu
                  95                 100                 105

 Leu Ala Ser Gln Lys Gly Ser Val Ser Glu Thr Ile Val Ile Asp
                 110                 115                 120

 Asp Glu Glu Asp Met Glu Thr Asn Gln Gly Gln Glu Lys Asn Ser
                 125                 130                 135

 Ser Asn Phe Ile Glu Arg Arg Pro Pro Glu Thr Lys Asn Arg Thr
                 140                 145                 150

 Asn Asp Val Asp Phe Ser Thr Ser Ser Phe Ser Arg Ser Lys Val
                 155                 160                 165

 Asn Ala Gly Met Gly Asn Ser Gly Ile Thr Thr Glu Pro Asp Ser
                 170                 175                 180

 Glu Ile Gln Ile Ala Asn Val Thr Thr Leu Glu Thr Gly Val Ser
                 185                 190                 195

 Ser Val Asn Asp Gly Gln Leu Glu Asn Thr Asp Gly Arg Asp Met
                 200                 205                 210

 Asn Leu Met Ile Thr His Val Thr Ser Leu Gln Asn Thr Asn Leu
                 215                 220                 225

 Gly Asp Val Ser Asn Gly Leu Gln Ser Ser Asn Phe Gly Val Asn
                 230                 235                 240

 Ile Gln Thr Tyr Thr Pro Ser Leu Thr Ser Gln Thr Lys Thr Gly
                 245                 250                 255

 Val Gly Pro Phe Asn Pro Gly Arg Met Asn Val Ala Gly Asp Val
                 260                 265                 270

 Phe Gln Asn Gly Glu Ser Ala Thr His His Asn Pro Asp Ser Trp
                 275                 280                 285

 Ile Ser Gln Ser Ala Ser Phe Pro Arg Asn Gln Lys Gln Pro Gly
                 290                 295                 300

 Val Asp Ser Leu Ser Pro Val Ala Ser Leu Pro Lys Gln Ile Phe
                 305                 310                 315

 Gln Pro Ser Val Gln Gln Gln Pro Thr Lys Pro Val Lys Val Thr
                 320                 325                 330

 Cys Ala Asn Cys Lys Lys Pro Leu Gln Lys Gly Gln Thr Ala Tyr
                 335                 340                 345

 Gln Arg Lys Gly Ser Ala His Leu Phe Cys Ser Thr Thr Cys Leu
                 350                 355                 360

 Ser Ser Phe Ser His Lys Pro Ala Pro Lys Lys Leu Cys Val Met
                 365                 370                 375

 Cys Lys Lys Asp Ile Thr Thr Met Lys Gly Thr Ile Val Ala Gln
                 380                 385                 390

 Val Asp Ser Ser Glu Ser Phe Gln Glu Phe Cys Ser Thr Ser Cys
                 395                 400                 405

 Leu Ser Leu Tyr Glu Asp Lys Gln Asn Pro Thr Lys Gly Ala Leu
                 410                 415                 420

 Asn Lys Ser Arg Cys Thr Ile Cys Gly Lys Leu Thr Glu Ile Arg
                 425                 430                 435

 His Glu Val Ser Phe Lys Asn Met Thr His Lys Leu Cys Ser Asp
                 440                 445                 450

 His Cys Phe Asn Arg Tyr Arg Met Ala Asn Gly Leu Ile Met Asn
                 455                 460                 465

 Cys Cys Glu Gln Cys Gly Glu Tyr Leu Pro Ser Lys Gly Ala Gly
                 470                 475                 480

 Asn Asn Val Leu Val Ile Asp Gly Gln Gln Lys Arg Phe Cys Cys
                 485                 490                 495

 Gln Ser Cys Val Ser Glu Tyr Lys Gln Val Gly Ser His Pro Ser
                 500                 505                 510

 Phe Leu Lys Glu Val Arg Asp His Met Gln Asp Ser Phe Leu Met
                 515                 520                 525

 Gln Pro Glu Lys Tyr Gly Lys Leu Thr Thr Cys Thr Gly Cys Arg
                 530                 535                 540

 Thr Gln Cys Arg Phe Phe Asp Met Thr Gln Cys Ile Gly Pro Asn
                 545                 550                 555

 Gly Tyr Met Glu Pro Tyr Cys Ser Thr Ala Cys Met Asn Ser His
                 560                 565                 570

 Lys Thr Lys Tyr Ala Lys Ser Gln Ser Leu Gly Ile Ile Cys His
                 575                 580                 585

 Phe Cys Lys Arg Asn Ser Leu Pro Gln Tyr Gln Ala Thr Met Pro
                 590                 595                 600

 Asp Gly Lys Leu Tyr Asn Phe Cys Asn Ser Ser Cys Val Ala Lys
                 605                 610                 615

 Phe Gln Ala Leu Ser Met Gln Ser Ser Pro Asn Gly Gln Phe Val
                 620                 625                 630

 Ala Pro Ser Asp Ile Gln Leu Lys Cys Asn Tyr Cys Lys Asn Ser
                 635                 640                 645

 Phe Cys Ser Lys Pro Glu Ile Leu Glu Trp Glu Asn Lys Val His
                 650                 655                 660

 Gln Phe Cys Ser Lys Thr Cys Ser Asp Asp Tyr Lys Lys Leu His
                 665                 670                 675

 Cys Ile Val Thr Tyr Cys Glu Tyr Cys Gln Glu Glu Lys Thr Leu
                 680                 685                 690

 His Glu Thr Val Asn Phe Ser Gly Val Lys Arg Pro Phe Cys Ser
                 695                 700                 705

 Glu Gly Cys Lys Leu Leu Tyr Lys Gln Asp Phe Ala Arg Arg Leu
                 710                 715                 720

 Gly Leu Arg Cys Val Thr Cys Asn Tyr Cys Ser Gln Leu Cys Lys
                 725                 730                 735

 Lys Gly Ala Thr Lys Glu Leu Asp Gly Val Val Arg Asp Phe Cys
                 740                 745                 750

 Ser Glu Asp Cys Cys Lys Lys Phe Gln Asp Trp Tyr Tyr Lys Ala
                 755                 760                 765

 Ala Arg Cys Asp Cys Cys Lys Ser Gln Gly Thr Leu Lys Glu Arg
                 770                 775                 780

 Val Gln Trp Arg Gly Glu Met Lys His Phe Cys Asp Gln His Cys
                 785                 790                 795

 Leu Leu Arg Phe Tyr Cys Gln Gln Asn Glu Pro Asn Met Thr Thr
                 800                 805                 810

 Gln Lys Gly Pro Glu Asn Leu His Tyr Asp Gln Gly Cys Gln Thr
                 815                 820                 825

 Ser Arg Thr Lys Met Thr Gly Ser Ala Pro Pro Pro Ser Pro Thr
                 830                 835                 840

 Pro Asn Lys Glu Met Lys Asn Lys Ala Val Leu Cys Lys Pro Leu
                 845                 850                 855

 Thr Met Thr Lys Ala Thr Tyr Cys Lys Pro His Met Gln Thr Lys
                 860                 865                 870

 Ser Cys Gln Thr Asp Asp Thr Trp Arg Thr Glu Tyr Val Pro Val
                 875                 880                 885

 Pro Ile Pro Val Pro Val Tyr Ile Pro Val Pro Met His Met Tyr
                 890                 895                 900

 Ser Gln Asn Ile Pro Val Pro Thr Thr Val Pro Val Pro Val Pro
                 905                 910                 915

 Val Pro Val Phe Leu Pro Ala Pro Leu Asp Ser Ser Glu Lys Ile
                 920                 925                 930

 Pro Ala Ala Ile Glu Glu Leu Lys Ser Lys Val Ser Ser Asp Ala
                 935                 940                 945

 Leu Asp Thr Glu Leu Leu Thr Met Thr Asp Met Met Ser Glu Asp
                 950                 955                 960

 Glu Gly Lys Thr Glu Thr Thr Asn Ile Asn Ser Val Ile Ile Glu
                 965                 970                 975

 Thr Asp Ile Ile Gly Ser Asp Leu Leu Lys Asn Ser Asp Pro Glu
                 980                 985                 990

 Thr Gln Ser Ser Met Pro Asp Val Pro Tyr Glu Pro Asp Leu Asp
                 995                1000                1005

 Ile Glu Ile Asp Phe Pro Arg Ala Ala Glu Glu Leu Asp Met Glu
                1010                1015                1020

 Asn Glu Phe Leu Leu Pro Pro Val Phe Gly Glu Glu Tyr Glu Glu
                1025                1030                1035

 Gln Pro Arg Pro Arg Ser Lys Lys Lys Gly Ala Lys Arg Lys Ala
                1040                1045                1050

 Val Ser Gly Tyr Gln Ser His Asp Asp Ser Ser Asp Asn Ser Glu
                1055                1060                1065

 Cys Ser Phe Pro Phe Lys Tyr Thr Tyr Gly Val Asn Ala Trp Lys
                1070                1075                1080

 His Trp Val Lys Thr Arg Gln Leu Asp Glu Asp Leu Leu Val Leu
                1085                1090                1095

 Asp Glu Leu Lys Ser Ser Lys Ser Val Lys Leu Lys Glu Asp Leu
                1100                1105                1110

 Leu Ser His Thr Thr Ala Glu Leu Asn Tyr Gly Leu Ala His Phe
                1115                1120                1125

 Val Asn Glu Ile Arg Arg Pro Asn Gly Glu Asn Tyr Ala Pro Asp
                1130                1135                1140

 Ser Ile Tyr Tyr Leu Cys Leu Gly Ile Gln Glu Tyr Leu Cys Gly
                1145                1150                1155

 Ser Asn Arg Lys Asp Asn Ile Phe Ile Asp Pro Gly Tyr Gln Thr
                1160                1165                1170

 Phe Glu Gln Glu Leu Asn Lys Ile Leu Arg Ser Trp Gln Pro Ser
                1175                1180                1185

 Ile Leu Pro Asp Gly Ser Ile Phe Ser Arg Val Glu Glu Asp Tyr
                1190                1195                1200

 Leu Trp Arg Ile Lys Gln Leu Gly Ser His Ser Pro Val Ala Leu
                1205                1210                1215

 Leu Asn Thr Leu Phe Tyr Phe Asn Thr Lys Tyr Phe Gly Leu Lys
                1220                1225                1230

 Thr Val Glu Gln His Leu Arg Leu Ser Phe Gly Thr Val Phe Arg
                1235                1240                1245

 His Trp Lys Lys Asn Pro Leu Thr Met Glu Asn Lys Ala Cys Leu
                1250                1255                1260

 Arg Tyr Gln Val Ser Ser Leu Cys Gly Thr Asp Asn Glu Asp Lys
                1265                1270                1275

 Ile Thr Thr Gly Lys Arg Lys His Glu Asp Asp Glu Pro Val Phe
                1280                1285                1290

 Glu Gln Ile Glu Asn Thr Ala Asn Pro Ser Arg Cys Pro Val Lys
                1295                1300                1305

 Met Phe Glu Cys Tyr Leu Ser Lys Ser Pro Gln Asn Leu Asn Gln
                1310                1315                1320

 Arg Met Asp Val Phe Tyr Leu Gln Pro Glu Cys Ser Ser Ser Thr
                1325                1330                1335

 Asp Ser Pro Val Trp Tyr Thr Ser Thr Ser Leu Asp Arg Asn Thr
                1340                1345                1350

 Leu Glu Asn Met Leu Val Arg Val Leu Leu Val Lys Asp Ile Tyr
                1355                1360                1365

 Asp Lys Asp Asn Tyr Glu Leu Asp Glu Asp Thr Asp
                1370                1375

<210> 2210
<211> 7785
<212> DNA
<213> Homo sapien

<400> 2210
 ctcactgtcc ctggaatctt caagggagtt actgcattac atcatcagaa 50

 acaaggcatt tctatattac tatggaaaga tttcgtctgg agaagaagtt 100

 acctggtcct gatgaagaag ctgttgtgga tcttggcaaa actagctcaa 150

 ctgtgaacac caagtttgaa aaagaagaac tagaaagtca tagagctgta 200

 tatattggtg ttcacgtccc gtttagtaaa gagagtcgtc ggcgtcatag 250

 gcatcgcgga cacaaacatc accaccggag gagaaaagat aaagaatcag 300

 ataaagaaga tggacgggaa tctccttctt atgatacacc atcccagaga 350

 gttcagttta tccttggtac tgaagatgat gatgaagaac atattcccca 400

 tgatctcttc acggaaatgg atgaactgtg ttacagagat ggagaagaat 450

 atgaatggaa agaaactgct agatggctga aatttgaaga ggatgttgaa 500

 gatggcggtg accgatggag taaaccttat gtggcaactc tctctttgca 550

 cagtcttttt gaactaagga gttgcatcct caatggaaca gtcatgctgg 600

 atatgagagc aagcactcta gatgaaatag cagatatggt attagacaac 650

 atgatagctt ctggccaatt agacgagtcc atacgagaga atgtcagaga 700

 agctcttctg aagagacatc atcatcagaa tgagaaaaga ttcaccagtc 750

 ggattcctct tgttcgatct tttgcagata taggcaagaa acattctgac 800

 cctcacttgc ttgaaaggaa tggggaaggc ctttcagcct cccgccactc 850

 tttgcgaaca ggtctgtctg cctcaaacct ttccttgaga ggagaatcac 900

 ctttatctct tcttctcggt catcttcttc cttcttcaag agctggaacc 950

 cctgcaggct caaggtgtac aaccccagta cccacccctc aaaacagtcc 1000

 tccttctagc cctagcatca gccgcctgac ctccagaagt tcccaaaaga 1050

 gtcagcgtca ggccccagaa ctactggttt cacctgccag tgatgatatt 1100

 cccacagtag taattcatcc gcctgaggaa gacttagaag cagcgctgaa 1150

 aggcgaggag cagaagaatg aggaaaatgt tgacttaact ccaggtattt 1200

 tggcctctcc ccagtctgct cctggaaact tggacaatag taaaagtgga 1250

 gaaattaaag gtaatggaag tggtggaagc agagaaaata gtactgttga 1300

 cttcagcaag gttgatatga atttcatgag aaaaattcct acgggtgctg 1350

 aggcatccaa cgtcctggtg ggcgaagtag actttttgga aaggccaata 1400

 attgcatttg tgagactggc tcctgctgtc ctccttacag ggttgactga 1450

 ggtccctgtt ccaaccaggt ttttgttttt gttattgggt ccagcgggca 1500

 aggcaccaca gtaccatgaa attggacgat caatagccac tctcatgaca 1550

 gatgagattt tccatgatgt agcttataaa gcaaaagaca gaaatgacct 1600

 cttatctgga attgatgaat ttttagatca agtaactgtc ctacctccag 1650

 gagagtggga tccttctata cgcatagaac caccaaaaag tgtcccttct 1700

 caggaaaaga gaaagattcc tgtgtttcac aatggatcta cccccacact 1750

 gggtgagact cctaaagagg ccgctcatca tgctgggcct gagctacaga 1800

 ggactggacg gctttttggt ggtttgatac ttgacatcaa aaggaaagca 1850

 ccttttttct tgagtgactt caaggatgca ttaagcctgc agtgcctggc 1900

 ctcgattctt ttcctatact gtgcctgtat gtctcctgta atcacttttg 1950

 gagggctgct tggagaagct acagaaggca gaataagtgc aatagagtct 2000

 ctttttggag catcattaac tgggattgcc tattcattgt ttgctgggca 2050

 acctctaaca atattgggga gcacaggtcc agttctagtg tttgaaaaaa 2100

 ttttatataa attctgcaga gattatcaac tttcttatct gtctttaaga 2150

 accagtattg gtctgtggac ttcttttttg tgcattgttt tggttgcaac 2200

 agatgcaagc agccttgtgt gttatattac tcgatttaca gaagaggctt 2250

 ttgcagccct tatttgcatc atattcatct acgaggcttt ggagaagctc 2300

 tttgatttag gagaaacata tgcatttaat atgcacaaca acttagataa 2350

 actgaccagc tactcatgtg tatgtactga acctccaaat cccagcaatg 2400

 aaactctagc acaatggaag aaagataata taacagcaca caatatttcc 2450

 tggagaaatc ttactgtttc tgaatgtaaa aaacttcgtg gtgtattctt 2500

 ggggtcagct tgtggtcatc atggacctta tattccagat gtgctctttt 2550

 ggtgtgtcat cttgtttttc acaacatttt ttctgtcttc attcctcaag 2600

 caatttaaga ccaagcgtta ctttcctacc aaggtgcgat cgacaatcag 2650

 tgattttgct gtatttctca caatagtaat aatggttaca attgactacc 2700

 ttgtaggagt tccatctcct aaacttcatg ttcctgaaaa atttgagcct 2750

 actcatccag agagagggtg gatcataagc ccactgggag ataatccttg 2800

 gtggacctta ttaatagctg ctattcctgc tttgctttgt accattctca 2850

 tctttatgga tcaacaaatc acagctgtaa ttataaacag aaaggaacac 2900

 aaattgaaga aaggagctgg ctatcacctt gatttgctca tggttggcgt 2950

 tatgttggga gtttgctctg tcatgggact tccatggttt gtggctgcaa 3000

 cagtgttgtc aataagtcat gtcaacagct taaaagttga atctgaatgt 3050

 tctgctccag gggaacaacc caagtttttg ggaattcgtg aacagcgggt 3100

 tacagggcta atgattttta ttctaatggg cctctctgtg ttcatgactt 3150

 cagtcctaaa gtttattcca atgcctgttc tgtatggtgt tttcctttat 3200

 atgggagttt cctcattaaa aggaatccag ttatttgacc gtataaaatt 3250

 atttggaatg cctgctaagc atcagcctga tttgatatac ctccgttatg 3300

 tgccgctctg gaaggtccat attttcacag tcattcagct tacttgtttg 3350

 gtccttttat gggtgataaa agtttcagct gctgcagtgg tttttcccat 3400

 gatggttctt gcattagtgt ttgtgcgcaa actcatggac ctgtgtttca 3450

 cgaagagaga acttagttgg cttgatgatc ttatgccaga aagtaagaaa 3500

 aagaaagaag atgacaaaaa gaaaaaagag aaagaggaag ctgaacggat 3550

 gcttcaagac gatgatgata ctgtgcacct tccatttgaa gggggaagtc 3600

 tcttgcaaat tccagtcaag gccctaaaat atagtcctga taaacctgtg 3650

 agtgtgaaaa taagttttga agatgaacca agaaagaaat acgtggatgc 3700

 tgaaacttca ttatagaatt gaaccaagag gcattataca tatagatata 3750

 tacatatgta atgtgtgcgt atcatgtcac tatatataag aatattgtat 3800

 gtcatgctgt ttatgtgtga ctaccgggtt tttaaaagta gtgtctggag 3850

 tttgtaatga gcaccgtgga gactatgtat ttaatgaaat gctctctttg 3900

 aagtgaggta catggttctt aactattcaa atatttattc tgttagaaaa 3950

 aaaaaatttt ctgttttgca atagaaggat gtggagaaat gctttcagtc 4000

 tacttttctt aaatctctgt tcatcagtgg caattcgtaa aaaccttaag 4050

 tgatactttg tttatatgtt tataattttt aggtgtttcc tgaaattttc 4100

 acatattatt tcacttttgt tagtgcttta tgggaagaat agggagtcta 4150

 taccagtgct gtgggaaaaa tggtaacatt tcagggcttc tctatttgtg 4200

 tttcatttct gtagatgtcc atcgtgtttc actaactggc gttttcttag 4250

 ccatagagat gactgtagaa caatagaaac tttaataatg atagttttta 4300

 acttttatgt ttaaattttt tttaaatctt aaaaccttca tatctaggta 4350

 tccattgtga cagacaagta aaattgcagg tgatttgata attaagcacc 4400

 cataccattt ataacttctg aatttaaaaa gttatacaat gccagtttgc 4450

 aatagttgat tttgatgcct ttgtagaata ttttttctga atccttatgc 4500

 tcttttaaag ccaatgattc ccactctgtt ctctgccttg tctctctttg 4550

 tcttaaaatg ctttagtttc catcaggttc aagttcttga ctattattct 4600

 cttataagta gtaggcgtaa ataatcagga gttagaattc tctcagaagg 4650

 gtctatgatc agtattactt tattaagaat tacctttcat tttctcttta 4700

 tgttattctt tcacttttgt agattacatt taatagcttg ttacctgtga 4750

 ttttatttta aaatatttat tttgatatga tgcttaaata ttatataaac 4800

 atttggaaaa gtaacaaata gagtaaattg ttaatgtaaa tagttggtgc 4850

 ttactttcat ttatgtttat tatcttaaag caattgatag attttacatc 4900

 tttgatataa agcactgcca tatttatatt ttaaaaggaa attagacatt 4950

 ttatatgtag ctcagattaa tgacattttt attttgtgta ttagtttttg 5000

 cttttctgag ctttttaaag tctaacaaat ctttttagtc atcttttata 5050

 tacttttagt tccacatgaa ataaatgttg ttaagcctgt aggactggat 5100

 gaatggggtt gtgaaactga tttgacaaga gaataattta caaaaatcaa 5150

 atgagtattg agaagccaca gaaatatcaa aaatggtgac atcactatta 5200

 ggatgaaaat tttatgaaat tccaatgctc cctttaacca tataattaaa 5250

 ttacaaaggt atacataatt aatctaataa aggatcatga ggaatgccaa 5300

 aagctgaaat tttagcaagt ctggtgtttt aaattcatta taaactattt 5350

 attaactaat gtaatgtcct cctctaagac catattgtaa gagtcttgtt 5400

 aaaatgatgg attcaacttc tgcctcggat gagaggttgg aaatgtagct 5450

 gcttttcttt agaaaatatg tagctgtcat catttggtac tgcctaaaaa 5500

 gagttagact ctattggcaa ttgatagagt attacccacg gtgcttatta 5550

 ttgtttatga gcttccattg taatgattcc tttttatttg tagcagcata 5600

 attatttcca aagaccccag tatttgctgc tatttttaaa actcccctga 5650

 tgtacctgaa caagaggatt tcctcacatc atttccttgt gtctggacat 5700

 caggggtaac aactgtactt actttacagg aagaaatttt aaaactgaaa 5750

 actacctggg atcatagtgt ttctgtgatt ttatttaatt gtgtatagta 5800

 attatccagt gccagaaaaa ccgtcacttg caaaatactt tgcactcaaa 5850

 atgtttttac aatgcttcta aatgttactg gtttctgctt tcttttgact 5900

 acttgactga caaaatgatc tgactactcc atttaagagc aaaggtaact 5950

 catgtttaag taattaactg cttgttttaa gtgattatat ttcttccact 6000

 gtttttgaaa aataatcaaa gatagcattc attgagagac agtgacagat 6050

 ataatttact acatatattg atttttaaat aaagttgcct taaataagtg 6100

 tatgtaagca gtagtagttg ctatgtactg atttacctca aggtgcaaaa 6150

 taattaaacc tgtacatatt ccatttacaa aataaattca gccctgcact 6200

 ttctttagat gccttgattt ccagaatgga gcttagtgct actgaatacc 6250

 ctggccacag agccacctca ggatattctt ttctccaccc tagtttattt 6300

 atttatagat atctgtttac aaagtctgta gtaaatcctg atgctgacca 6350

 tctgaaatgt actttttttc tgaatgctgt ttcaatctaa aatagcagct 6400

 tttgagaaaa caatgatgta aattccttat gataaaagga tgattctata 6450

 tattctttaa tgatattaaa tatgccgaag ccaagcacac agtctttcta 6500

 aagtgtgtgt atgtttgtgt gaatgtgaat gatactgatc ttatatctgt 6550

 taaaagttgt tttaaaaagc tgtggcatcc cattgttcat atttgccaag 6600

 tcttctgtaa agatgtctag gacgaaatat tttatgtgct aatgcatgta 6650

 tttgtaaacc agatttgttt accactcaaa attaacttgt tttcttcatc 6700

 caaaaaagtt tatgtcttcc acgtacttaa attttctgtg tgggtataat 6750

 atagctttct aatttttttc tttcacaaag gcaggttcaa aattctgttg 6800

 aaagaaaaat gctttctgaa actgaggtat aacaccagag cttgctgttt 6850

 aaaggattat atgatgtaca tcagttctat aaatgtgctc agcagtttaa 6900

 catgtgaatc ctgttttaaa gtgctcagat ttcaactgtg taagccattg 6950

 atataacgct gtaattaaaa atgtttatat gaaataactt aatgttttaa 7000

 atttatttat gtagatcaca tcatttttat cagtatgcag tgcaaatatg 7050

 tgaaatgtct tttggtttat tccaacaatt atttatttta gaaagtaagt 7100

 ttaaagactt taaggacatt caaagtttaa aatagtgttc aaattgcaaa 7150

 atttggcaat cttcatataa attggtttct tttctaactt ttcaaaaact 7200

 aacattaaat gtcaattata ggaaaacata gttggaaatg taatcatccc 7250

 aaagatcatt tttaaaatga aatttaatta gcacatattg aacatttgac 7300

 ttaattgtta aaccccagtt ttgttttgtt tttttaatca gatttttgca 7350

 cactgattag tttttgtgtt gtggcttttg ttgctttatt attcaaggtt 7400

 tttttttttc tttccccatg ggggagattg tcttccaatg tttaactacg 7450

 tttaaataaa taaaaattga attttattgt tcatttatat aaaatctgat 7500

 accttgatgt aatttcacaa tacagttcca atttttatgg cttttataat 7550

 tacaatgata ttttcttcta taataaaatc caaagtaaac atttaaattg 7600

 tagaactgat atttttcatt tatatgaagt ataagcctct actgggtcta 7650

 tattgtgaat catcctgcct ttcaaatttg tttcataatt gttagatgaa 7700

 aactattttt ttggagatgt tactgaagtt gattgagcaa taaaagtcta 7750

 cttaattaaa aaaaaaaaaa aaaaaaaaaa aaaaa 7785

<210> 2211
<211> 1214
<212> PRT
<213> Homo sapien

<400> 2211
 Met Glu Arg Phe Arg Leu Glu Lys Lys Leu Pro Gly Pro Asp Glu
   1               5                  10                  15

 Glu Ala Val Val Asp Leu Gly Lys Thr Ser Ser Thr Val Asn Thr
                  20                  25                  30

 Lys Phe Glu Lys Glu Glu Leu Glu Ser His Arg Ala Val Tyr Ile
                  35                  40                  45

 Gly Val His Val Pro Phe Ser Lys Glu Ser Arg Arg Arg His Arg
                  50                  55                  60

 His Arg Gly His Lys His His His Arg Arg Arg Lys Asp Lys Glu
                  65                  70                  75

 Ser Asp Lys Glu Asp Gly Arg Glu Ser Pro Ser Tyr Asp Thr Pro
                  80                  85                  90

 Ser Gln Arg Val Gln Phe Ile Leu Gly Thr Glu Asp Asp Asp Glu
                  95                 100                 105

 Glu His Ile Pro His Asp Leu Phe Thr Glu Met Asp Glu Leu Cys
                 110                 115                 120

 Tyr Arg Asp Gly Glu Glu Tyr Glu Trp Lys Glu Thr Ala Arg Trp
                 125                 130                 135

 Leu Lys Phe Glu Glu Asp Val Glu Asp Gly Gly Asp Arg Trp Ser
                 140                 145                 150

 Lys Pro Tyr Val Ala Thr Leu Ser Leu His Ser Leu Phe Glu Leu
                 155                 160                 165

 Arg Ser Cys Ile Leu Asn Gly Thr Val Met Leu Asp Met Arg Ala
                 170                 175                 180

 Ser Thr Leu Asp Glu Ile Ala Asp Met Val Leu Asp Asn Met Ile
                 185                 190                 195

 Ala Ser Gly Gln Leu Asp Glu Ser Ile Arg Glu Asn Val Arg Glu
                 200                 205                 210

 Ala Leu Leu Lys Arg His His His Gln Asn Glu Lys Arg Phe Thr
                 215                 220                 225

 Ser Arg Ile Pro Leu Val Arg Ser Phe Ala Asp Ile Gly Lys Lys
                 230                 235                 240

 His Ser Asp Pro His Leu Leu Glu Arg Asn Gly Glu Gly Leu Ser
                 245                 250                 255

 Ala Ser Arg His Ser Leu Arg Thr Gly Leu Ser Ala Ser Asn Leu
                 260                 265                 270

 Ser Leu Arg Gly Glu Ser Pro Leu Ser Leu Leu Leu Gly His Leu
                 275                 280                 285

 Leu Pro Ser Ser Arg Ala Gly Thr Pro Ala Gly Ser Arg Cys Thr
                 290                 295                 300

 Thr Pro Val Pro Thr Pro Gln Asn Ser Pro Pro Ser Ser Pro Ser
                 305                 310                 315

 Ile Ser Arg Leu Thr Ser Arg Ser Ser Gln Lys Ser Gln Arg Gln
                 320                 325                 330

 Ala Pro Glu Leu Leu Val Ser Pro Ala Ser Asp Asp Ile Pro Thr
                 335                 340                 345

 Val Val Ile His Pro Pro Glu Glu Asp Leu Glu Ala Ala Leu Lys
                 350                 355                 360

 Gly Glu Glu Gln Lys Asn Glu Glu Asn Val Asp Leu Thr Pro Gly
                 365                 370                 375

 Ile Leu Ala Ser Pro Gln Ser Ala Pro Gly Asn Leu Asp Asn Ser
                 380                 385                 390

 Lys Ser Gly Glu Ile Lys Gly Asn Gly Ser Gly Gly Ser Arg Glu
                 395                 400                 405

 Asn Ser Thr Val Asp Phe Ser Lys Val Asp Met Asn Phe Met Arg
                 410                 415                 420

 Lys Ile Pro Thr Gly Ala Glu Ala Ser Asn Val Leu Val Gly Glu
                 425                 430                 435

 Val Asp Phe Leu Glu Arg Pro Ile Ile Ala Phe Val Arg Leu Ala
                 440                 445                 450

 Pro Ala Val Leu Leu Thr Gly Leu Thr Glu Val Pro Val Pro Thr
                 455                 460                 465

 Arg Phe Leu Phe Leu Leu Leu Gly Pro Ala Gly Lys Ala Pro Gln
                 470                 475                 480

 Tyr His Glu Ile Gly Arg Ser Ile Ala Thr Leu Met Thr Asp Glu
                 485                 490                 495

 Ile Phe His Asp Val Ala Tyr Lys Ala Lys Asp Arg Asn Asp Leu
                 500                 505                 510

 Leu Ser Gly Ile Asp Glu Phe Leu Asp Gln Val Thr Val Leu Pro
                 515                 520                 525

 Pro Gly Glu Trp Asp Pro Ser Ile Arg Ile Glu Pro Pro Lys Ser
                 530                 535                 540

 Val Pro Ser Gln Glu Lys Arg Lys Ile Pro Val Phe His Asn Gly
                 545                 550                 555

 Ser Thr Pro Thr Leu Gly Glu Thr Pro Lys Glu Ala Ala His His
                 560                 565                 570

 Ala Gly Pro Glu Leu Gln Arg Thr Gly Arg Leu Phe Gly Gly Leu
                 575                 580                 585

 Ile Leu Asp Ile Lys Arg Lys Ala Pro Phe Phe Leu Ser Asp Phe
                 590                 595                 600

 Lys Asp Ala Leu Ser Leu Gln Cys Leu Ala Ser Ile Leu Phe Leu
                 605                 610                 615

 Tyr Cys Ala Cys Met Ser Pro Val Ile Thr Phe Gly Gly Leu Leu
                 620                 625                 630

 Gly Glu Ala Thr Glu Gly Arg Ile Ser Ala Ile Glu Ser Leu Phe
                 635                 640                 645

 Gly Ala Ser Leu Thr Gly Ile Ala Tyr Ser Leu Phe Ala Gly Gln
                 650                 655                 660

 Pro Leu Thr Ile Leu Gly Ser Thr Gly Pro Val Leu Val Phe Glu
                 665                 670                 675

 Lys Ile Leu Tyr Lys Phe Cys Arg Asp Tyr Gln Leu Ser Tyr Leu
                 680                 685                 690

 Ser Leu Arg Thr Ser Ile Gly Leu Trp Thr Ser Phe Leu Cys Ile
                 695                 700                 705

 Val Leu Val Ala Thr Asp Ala Ser Ser Leu Val Cys Tyr Ile Thr
                 710                 715                 720

 Arg Phe Thr Glu Glu Ala Phe Ala Ala Leu Ile Cys Ile Ile Phe
                 725                 730                 735

 Ile Tyr Glu Ala Leu Glu Lys Leu Phe Asp Leu Gly Glu Thr Tyr
                 740                 745                 750

 Ala Phe Asn Met His Asn Asn Leu Asp Lys Leu Thr Ser Tyr Ser
                 755                 760                 765

 Cys Val Cys Thr Glu Pro Pro Asn Pro Ser Asn Glu Thr Leu Ala
                 770                 775                 780

 Gln Trp Lys Lys Asp Asn Ile Thr Ala His Asn Ile Ser Trp Arg
                 785                 790                 795

 Asn Leu Thr Val Ser Glu Cys Lys Lys Leu Arg Gly Val Phe Leu
                 800                 805                 810

 Gly Ser Ala Cys Gly His His Gly Pro Tyr Ile Pro Asp Val Leu
                 815                 820                 825

 Phe Trp Cys Val Ile Leu Phe Phe Thr Thr Phe Phe Leu Ser Ser
                 830                 835                 840

 Phe Leu Lys Gln Phe Lys Thr Lys Arg Tyr Phe Pro Thr Lys Val
                 845                 850                 855

 Arg Ser Thr Ile Ser Asp Phe Ala Val Phe Leu Thr Ile Val Ile
                 860                 865                 870

 Met Val Thr Ile Asp Tyr Leu Val Gly Val Pro Ser Pro Lys Leu
                 875                 880                 885

 His Val Pro Glu Lys Phe Glu Pro Thr His Pro Glu Arg Gly Trp
                 890                 895                 900

 Ile Ile Ser Pro Leu Gly Asp Asn Pro Trp Trp Thr Leu Leu Ile
                 905                 910                 915

 Ala Ala Ile Pro Ala Leu Leu Cys Thr Ile Leu Ile Phe Met Asp
                 920                 925                 930

 Gln Gln Ile Thr Ala Val Ile Ile Asn Arg Lys Glu His Lys Leu
                 935                 940                 945

 Lys Lys Gly Ala Gly Tyr His Leu Asp Leu Leu Met Val Gly Val
                 950                 955                 960

 Met Leu Gly Val Cys Ser Val Met Gly Leu Pro Trp Phe Val Ala
                 965                 970                 975

 Ala Thr Val Leu Ser Ile Ser His Val Asn Ser Leu Lys Val Glu
                 980                 985                 990

 Ser Glu Cys Ser Ala Pro Gly Glu Gln Pro Lys Phe Leu Gly Ile
                 995                1000                1005

 Arg Glu Gln Arg Val Thr Gly Leu Met Ile Phe Ile Leu Met Gly
                1010                1015                1020

 Leu Ser Val Phe Met Thr Ser Val Leu Lys Phe Ile Pro Met Pro
                1025                1030                1035

 Val Leu Tyr Gly Val Phe Leu Tyr Met Gly Val Ser Ser Leu Lys
                1040                1045                1050

 Gly Ile Gln Leu Phe Asp Arg Ile Lys Leu Phe Gly Met Pro Ala
                1055                1060                1065

 Lys His Gln Pro Asp Leu Ile Tyr Leu Arg Tyr Val Pro Leu Trp
                1070                1075                1080

 Lys Val His Ile Phe Thr Val Ile Gln Leu Thr Cys Leu Val Leu
                1085                1090                1095

 Leu Trp Val Ile Lys Val Ser Ala Ala Ala Val Val Phe Pro Met
                1100                1105                1110

 Met Val Leu Ala Leu Val Phe Val Arg Lys Leu Met Asp Leu Cys
                1115                1120                1125

 Phe Thr Lys Arg Glu Leu Ser Trp Leu Asp Asp Leu Met Pro Glu
                1130                1135                1140

 Ser Lys Lys Lys Lys Glu Asp Asp Lys Lys Lys Lys Glu Lys Glu
                1145                1150                1155

 Glu Ala Glu Arg Met Leu Gln Asp Asp Asp Asp Thr Val His Leu
                1160                1165                1170

 Pro Phe Glu Gly Gly Ser Leu Leu Gln Ile Pro Val Lys Ala Leu
                1175                1180                1185

 Lys Tyr Ser Pro Asp Lys Pro Val Ser Val Lys Ile Ser Phe Glu
                1190                1195                1200

 Asp Glu Pro Arg Lys Lys Tyr Val Asp Ala Glu Thr Ser Leu
                1205                1210

<210> 2212
<211> 1630
<212> DNA
<213> Homo sapien

<400> 2212
 ccatccagtg ccttccgcag cgccgctaaa gcgcagttct cgttggtgta 50

 actttttctt ttttttttca gccacttccg gctcctgcgt cgctccggaa 100

 gcctgcgagt tccggaagcc ttggtaatcc agattcggct aggaaaagac 150

 aagctttcca gagaatgttt cagagaaagt tacgtggagc gtgggcgttt 200

 cgcagactcc taagtggtct ggaacctaac ctgcagtgtc tctgagcttc 250

 tggcaagtat gaggcaagga tttcacagaa gaacttggag caaaaattcc 300

 cactgtcata gctataggct gtccagtctt gagggagctg caggaacagg 350

 aaaaagagac cttcagagaa gacatggctt ccagaaaaga gaatgcgaag 400

 agtgcaaaca gagtgctaag aataagccag ttggatgcac ttgaactaaa 450

 caaggccctg gagcagctag tttggtccca gtttactcag tgctttcatg 500

 gatttaaacc tgggctgtta gctcgctttg agccagaggt gaaagcgtgc 550

 ttatgggttt tcttgtggag attcaccatc tactccaaaa atgccacagt 600

 gggacagtca gttttgaata ttaagtacaa aaatgatttt tcccctaacc 650

 tgagatatca gccacccagt aaaaatcaaa aaatctggta tgctgtttgt 700

 acaattggtg gcaggtggtt agaagaacga tgctatgatt tgtttcgaaa 750

 ccatcattta gcatcatttg ggaaagtcaa gcagtgtgtg aattttgtga 800

 ttggactttt gaaattaggt gggctgatta attttttgat tttccttcag 850

 aggggaaagt ttgcaacttt gacagaacgt ctcctaggta ttcattctgt 900

 attttgcaag cctcaaaaca tacgtgaagt tggctttgaa tacatgaata 950

 gggaacttct ctggcatggt tttgctgaat ttctgatttt tctcttacca 1000

 cttatcaatg tccagaagtt gaaagccaag ctgtcttcat ggtgtattcc 1050

 tcttactggt gcacctaata gtgacaatac attagccacc agtggcaaag 1100

 aatgcgctct atgtggagag tggcccacca tgcctcacac cataggatgt 1150

 gagcatattt tctgttattt ctgtgctaag agtagtttct tatttgacgt 1200

 gtactttact tgtcctaagt gtggcacaga agtacacagt ctgcagccac 1250

 tgaaatcagg aatcgagatg tcagaagtaa atgctcttta gaaactaaaa 1300

 ttgcttcctt tgaggaaaaa aatgcaccgt gtttaaattc ttaatattag 1350

 tcatcctaag tataccattt atgtatcctt tataaggaat gtgctcctag 1400

 ccactgtctt ctcctttcca ggcatgactg aaatctaatc actggaaacc 1450

 atgtgattct aaatatatta tgtaaatgtt aatgtattat gttttttaaa 1500

 tcattgcatt caatttttaa tgtcaagaat aatggacagc ttttgtcagg 1550

 tgactactaa caatgctcct tcattttact acttcttaaa acaaggttgg 1600

 attctaaaga taaagatttt ggagactctg 1630

<210> 2213
<211> 305
<212> PRT
<213> Homo sapien

<400> 2213
 Met Ala Ser Arg Lys Glu Asn Ala Lys Ser Ala Asn Arg Val Leu
   1               5                  10                  15

 Arg Ile Ser Gln Leu Asp Ala Leu Glu Leu Asn Lys Ala Leu Glu
                  20                  25                  30

 Gln Leu Val Trp Ser Gln Phe Thr Gln Cys Phe His Gly Phe Lys
                  35                  40                  45

 Pro Gly Leu Leu Ala Arg Phe Glu Pro Glu Val Lys Ala Cys Leu
                  50                  55                  60

 Trp Val Phe Leu Trp Arg Phe Thr Ile Tyr Ser Lys Asn Ala Thr
                  65                  70                  75

 Val Gly Gln Ser Val Leu Asn Ile Lys Tyr Lys Asn Asp Phe Ser
                  80                  85                  90

 Pro Asn Leu Arg Tyr Gln Pro Pro Ser Lys Asn Gln Lys Ile Trp
                  95                 100                 105

 Tyr Ala Val Cys Thr Ile Gly Gly Arg Trp Leu Glu Glu Arg Cys
                 110                 115                 120

 Tyr Asp Leu Phe Arg Asn His His Leu Ala Ser Phe Gly Lys Val
                 125                 130                 135

 Lys Gln Cys Val Asn Phe Val Ile Gly Leu Leu Lys Leu Gly Gly
                 140                 145                 150

 Leu Ile Asn Phe Leu Ile Phe Leu Gln Arg Gly Lys Phe Ala Thr
                 155                 160                 165

 Leu Thr Glu Arg Leu Leu Gly Ile His Ser Val Phe Cys Lys Pro
                 170                 175                 180

 Gln Asn Ile Arg Glu Val Gly Phe Glu Tyr Met Asn Arg Glu Leu
                 185                 190                 195

 Leu Trp His Gly Phe Ala Glu Phe Leu Ile Phe Leu Leu Pro Leu
                 200                 205                 210

 Ile Asn Val Gln Lys Leu Lys Ala Lys Leu Ser Ser Trp Cys Ile
                 215                 220                 225

 Pro Leu Thr Gly Ala Pro Asn Ser Asp Asn Thr Leu Ala Thr Ser
                 230                 235                 240

 Gly Lys Glu Cys Ala Leu Cys Gly Glu Trp Pro Thr Met Pro His
                 245                 250                 255

 Thr Ile Gly Cys Glu His Ile Phe Cys Tyr Phe Cys Ala Lys Ser
                 260                 265                 270

 Ser Phe Leu Phe Asp Val Tyr Phe Thr Cys Pro Lys Cys Gly Thr
                 275                 280                 285

 Glu Val His Ser Leu Gln Pro Leu Lys Ser Gly Ile Glu Met Ser
                 290                 295                 300

 Glu Val Asn Ala Leu
                 305

<210> 2214
<211> 4450
<212> DNA
<213> Homo sapien

<400> 2214
 acccacgcgc agcggccgga gatgcagcgg ggcgccgcgc tgtgcctgcg 50

 actgtggctc tgcctgggac tcctggacgg cctggtgagt gactactcca 100

 tgaccccccc gaccttgaac atcacggagg agtcacacgt catcgacacc 150

 ggtgacagcc tgtccatctc ctgcagggga cagcaccccc tcgagtgggc 200

 ttggccagga gctcaggagg cgccagccac cggagacaag gacagcgagg 250

 acacgggggt ggtgcgagac tgcgagggca cagacgccag gccctactgc 300

 aaggtgttgc tgctgcacga ggtacatgcc aacgacacag gcagctacgt 350

 ctgctactac aagtacatca aggcacgcat cgagggcacc acggccgcca 400

 gctcctacgt gttcgtgaga gactttgagc agccattcat caacaagcct 450

 gacacgctct tggtcaacag gaaggacgcc atgtgggtgc cctgtctggt 500

 gtccatcccc ggcctcaatg tcacgctgcg ctcgcaaagc tcggtgctgt 550

 ggccagacgg gcaggaggtg gtgtgggatg accggcgggg catgctcgtg 600

 tccacgccac tgctgcacga tgccctgtac ctgcagtgcg agaccacctg 650

 gggagaccag gacttccttt ccaacccctt cctggtgcac atcacaggca 700

 acgagctcta tgacatccag ctgttgccca ggaagtcgct ggagctgctg 750

 gtaggggaga agctggtcct caactgcacc gtgtgggctg agtttaactc 800

 aggtgtcacc tttgactggg actacccagg gaagcaggca gagcggggta 850

 agtgggtgcc cgagcgacgc tcccaacaga cccacacaga actctccagc 900

 atcctgacca tccacaacgt cagccagcac gacctgggct cgtatgtgtg 950

 caaggccaac aacggcatcc agcgatttcg ggagagcacc gaggtcattg 1000

 tgcatgaaaa tcccttcatc agcgtcgagt ggctcaaagg acccatcctg 1050

 gaggccacgg caggagacga gctggtgaag ctgcccgtga agctggcagc 1100

 gtaccccccg cccgagttcc agtggtacaa ggatggaaag gcactgtccg 1150

 ggcgccacag tccacatgcc ctggtgctca aggaggtgac agaggccagc 1200

 acaggcacct acaccctcgc cctgtggaac tccgctgctg gcctgaggcg 1250

 caacatcagc ctggagctgg tggtgaatgt gcccccccag atacatgaga 1300

 aggaggcctc ctcccccagc atctactcgc gtcacagccg ccaggccctc 1350

 acctgcacgg cctacggggt gcccctgcct ctcagcatcc agtggcactg 1400

 gcggccctgg acaccctgca agatgtttgc ccagcgtagt ctccggcggc 1450

 ggcagcagca agacctcatg ccacagtgcc gtgactggag ggcggtgacc 1500

 acgcaggatg ccgtgaaccc catcgagagc ctggacacct ggaccgagtt 1550

 tgtggaggga aagaataaga ctgtgagcaa gctggtgatc cagaatgcca 1600

 acgtgtctgc catgtacaag tgtgtggtct ccaacaaggt gggccaggat 1650

 gagcggctca tctacttcta tgtgaccacc atccccgacg gcttcaccat 1700

 cgaatccaag ccatccgagg agctactaga gggccagccg gtgctcctga 1750

 gctgccaagc cgacagctac aagtacgagc atctgcgctg gtaccgcctc 1800

 aacctgtcca cgctgcacga tgcgcacggg aacccgcttc tgctcgactg 1850

 caagaacgtg catctgttcg ccacccctct ggccgccagc ctggaggagg 1900

 tggcacctgg ggcgcgccac gccacgctca gcctgagtat cccccgcgtc 1950

 gcgcccgagc acgagggcca ctatgtgtgc gaagtgcaag accggcgcag 2000

 ccatgacaag cactgccaca agaagtacct gtcggtgcag gccctggaag 2050

 cccctcggct cacgcagaac ttgaccgacc tcctggtgaa cgtgagcgac 2100

 tcgctggaga tgcagtgctt ggtggccgga gcgcacgcgc ccagcatcgt 2150

 gtggtacaaa gacgagaggc tgctggagga aaagtctgga gtcgacttgg 2200

 cggactccaa ccagaagctg agcatccagc gcgtgcgcga ggaggatgcg 2250

 ggaccgtatc tgtgcagcgt gtgcagaccc aagggctgcg tcaactcctc 2300

 cgccagcgtg gccgtggaag gctccgagga taagggcagc atggagatcg 2350

 tgatccttgt cggtaccggc gtcatcgctg tcttcttctg ggtcctcctc 2400

 ctcctcatct tctgtaacat gaggaggccg gcccacgcag acatcaagac 2450

 gggctacctg tccatcatca tggaccccgg ggaggtgcct ctggaggagc 2500

 aatgcgaata cctgtcctac gatgccagcc agtgggaatt cccccgagag 2550

 cggctgcacc tggggagagt gctcggctac ggcgccttcg ggaaggtggt 2600

 ggaagcctcc gctttcggca tccacaaggg cagcagctgt gacaccgtgg 2650

 ccgtgaaaat gctgaaagag ggcgccacgg ccagcgagca gcgcgcgctg 2700

 atgtcggagc tcaagatcct cattcacatc ggcaaccacc tcaacgtggt 2750

 caacctcctc ggggcgtgca ccaagccgca gggccccctc atggtgatcg 2800

 tggagttctg caagtacggc aacctctcca acttcctgcg cgccaagcgg 2850

 gacgccttca gcccctgcgc ggagaagtct cccgagcagc gcggacgctt 2900

 ccgcgccatg gtggagctcg ccaggctgga tcggaggcgg ccggggagca 2950

 gcgacagggt cctcttcgcg cggttctcga agaccgaggg cggagcgagg 3000

 cgggcttctc cagaccaaga agctgaggac ctgtggctga gcccgctgac 3050

 catggaagat cttgtctgct acagcttcca ggtggccaga gggatggagt 3100

 tcctggcttc ccgaaagtgc atccacagag acctggctgc tcggaacatt 3150

 ctgctgtcgg aaagcgacgt ggtgaagatc tgtgactttg gccttgcccg 3200

 ggacatctac aaagaccccg actacgtccg caagggcagt gcccggctgc 3250

 ccctgaagtg gatggcccct gaaagcatct tcgacaaggt gtacaccacg 3300

 cagagtgacg tgtggtcctt tggggtgctt ctctgggaga tcttctctct 3350

 gggggcctcc ccgtaccctg gggtgcagat caatgaggag ttctgccagc 3400

 gcgtgagaga cggcacaagg atgagggccc cggagctggc cactcccgcc 3450

 atacgccaca tcatgctgaa ctgctggtcc ggagacccca aggcgagacc 3500

 tgcattctcg gacctggtgg agatcctggg ggacctgctc cagggcaggg 3550

 gcctgcaaga ggaagaggag gtctgcatgg ccccgcgcag ctctcagagc 3600

 tcagaagagg gcagcttctc gcaggtgtcc accatggccc tacacatcgc 3650

 ccaggctgac gctgaggaca gcccgccaag cctgcagcgc cacagcctgg 3700

 ccgccaggta ttacaactgg gtgtcctttc ccgggtgcct ggccagaggg 3750

 gctgagaccc gtggttcctc caggatgaag acatttgagg aattccccat 3800

 gaccccaacg acctacaaag gctctgtgga caaccagaca gacagtggga 3850

 tggtgctggc ctcggaggag tttgagcaga tagagagcag gcatagacaa 3900

 gaaagcggct tcaggtagct gaagcagaga gagagaaggc agcatacgtc 3950

 agcattttct tctctgcact tataagaaag atcaaagact ttaagacttt 4000

 cgctatttct tctactgcta tctactacaa acttcaaaga ggaaccagga 4050

 ggacaagagg agcatgaaag tggacaagga gtgtgaccac tgaagcacca 4100

 cagggagggg ttaggcctcc ggatgactgc gggcaggcct ggataatatc 4150

 cagcctccca caagaagctg gtggagcaga gtgttccctg actcctccaa 4200

 ggaaagggag acgccctttc atggtctgct gagtaacagg tgccttccca 4250

 gacactggcg ttactgcttg accaaagagc cctcaagcgg cccttatgcc 4300

 agcgtgacag agggctcacc tcttgccttc taggtcactt ctcacaatgt 4350

 cccttcagca cctgaccctg tgcccgccga ttattccttg gtaatatgag 4400

 taatacatca aagagtagta ttaaaagcta attaatcatg tttataaaaa 4450

<210> 2215
<211> 1298
<212> PRT
<213> Homo sapien

<400> 2215
 Met Gln Arg Gly Ala Ala Leu Cys Leu Arg Leu Trp Leu Cys Leu
   1               5                  10                  15

 Gly Leu Leu Asp Gly Leu Val Ser Asp Tyr Ser Met Thr Pro Pro
                  20                  25                  30

 Thr Leu Asn Ile Thr Glu Glu Ser His Val Ile Asp Thr Gly Asp
                  35                  40                  45

 Ser Leu Ser Ile Ser Cys Arg Gly Gln His Pro Leu Glu Trp Ala
                  50                  55                  60

 Trp Pro Gly Ala Gln Glu Ala Pro Ala Thr Gly Asp Lys Asp Ser
                  65                  70                  75

 Glu Asp Thr Gly Val Val Arg Asp Cys Glu Gly Thr Asp Ala Arg
                  80                  85                  90

 Pro Tyr Cys Lys Val Leu Leu Leu His Glu Val His Ala Asn Asp
                  95                 100                 105

 Thr Gly Ser Tyr Val Cys Tyr Tyr Lys Tyr Ile Lys Ala Arg Ile
                 110                 115                 120

 Glu Gly Thr Thr Ala Ala Ser Ser Tyr Val Phe Val Arg Asp Phe
                 125                 130                 135

 Glu Gln Pro Phe Ile Asn Lys Pro Asp Thr Leu Leu Val Asn Arg
                 140                 145                 150

 Lys Asp Ala Met Trp Val Pro Cys Leu Val Ser Ile Pro Gly Leu
                 155                 160                 165

 Asn Val Thr Leu Arg Ser Gln Ser Ser Val Leu Trp Pro Asp Gly
                 170                 175                 180

 Gln Glu Val Val Trp Asp Asp Arg Arg Gly Met Leu Val Ser Thr
                 185                 190                 195

 Pro Leu Leu His Asp Ala Leu Tyr Leu Gln Cys Glu Thr Thr Trp
                 200                 205                 210

 Gly Asp Gln Asp Phe Leu Ser Asn Pro Phe Leu Val His Ile Thr
                 215                 220                 225

 Gly Asn Glu Leu Tyr Asp Ile Gln Leu Leu Pro Arg Lys Ser Leu
                 230                 235                 240

 Glu Leu Leu Val Gly Glu Lys Leu Val Leu Asn Cys Thr Val Trp
                 245                 250                 255

 Ala Glu Phe Asn Ser Gly Val Thr Phe Asp Trp Asp Tyr Pro Gly
                 260                 265                 270

 Lys Gln Ala Glu Arg Gly Lys Trp Val Pro Glu Arg Arg Ser Gln
                 275                 280                 285

 Gln Thr His Thr Glu Leu Ser Ser Ile Leu Thr Ile His Asn Val
                 290                 295                 300

 Ser Gln His Asp Leu Gly Ser Tyr Val Cys Lys Ala Asn Asn Gly
                 305                 310                 315

 Ile Gln Arg Phe Arg Glu Ser Thr Glu Val Ile Val His Glu Asn
                 320                 325                 330

 Pro Phe Ile Ser Val Glu Trp Leu Lys Gly Pro Ile Leu Glu Ala
                 335                 340                 345

 Thr Ala Gly Asp Glu Leu Val Lys Leu Pro Val Lys Leu Ala Ala
                 350                 355                 360

 Tyr Pro Pro Pro Glu Phe Gln Trp Tyr Lys Asp Gly Lys Ala Leu
                 365                 370                 375

 Ser Gly Arg His Ser Pro His Ala Leu Val Leu Lys Glu Val Thr
                 380                 385                 390

 Glu Ala Ser Thr Gly Thr Tyr Thr Leu Ala Leu Trp Asn Ser Ala
                 395                 400                 405

 Ala Gly Leu Arg Arg Asn Ile Ser Leu Glu Leu Val Val Asn Val
                 410                 415                 420

 Pro Pro Gln Ile His Glu Lys Glu Ala Ser Ser Pro Ser Ile Tyr
                 425                 430                 435

 Ser Arg His Ser Arg Gln Ala Leu Thr Cys Thr Ala Tyr Gly Val
                 440                 445                 450

 Pro Leu Pro Leu Ser Ile Gln Trp His Trp Arg Pro Trp Thr Pro
                 455                 460                 465

 Cys Lys Met Phe Ala Gln Arg Ser Leu Arg Arg Arg Gln Gln Gln
                 470                 475                 480

 Asp Leu Met Pro Gln Cys Arg Asp Trp Arg Ala Val Thr Thr Gln
                 485                 490                 495

 Asp Ala Val Asn Pro Ile Glu Ser Leu Asp Thr Trp Thr Glu Phe
                 500                 505                 510

 Val Glu Gly Lys Asn Lys Thr Val Ser Lys Leu Val Ile Gln Asn
                 515                 520                 525

 Ala Asn Val Ser Ala Met Tyr Lys Cys Val Val Ser Asn Lys Val
                 530                 535                 540

 Gly Gln Asp Glu Arg Leu Ile Tyr Phe Tyr Val Thr Thr Ile Pro
                 545                 550                 555

 Asp Gly Phe Thr Ile Glu Ser Lys Pro Ser Glu Glu Leu Leu Glu
                 560                 565                 570

 Gly Gln Pro Val Leu Leu Ser Cys Gln Ala Asp Ser Tyr Lys Tyr
                 575                 580                 585

 Glu His Leu Arg Trp Tyr Arg Leu Asn Leu Ser Thr Leu His Asp
                 590                 595                 600

 Ala His Gly Asn Pro Leu Leu Leu Asp Cys Lys Asn Val His Leu
                 605                 610                 615

 Phe Ala Thr Pro Leu Ala Ala Ser Leu Glu Glu Val Ala Pro Gly
                 620                 625                 630

 Ala Arg His Ala Thr Leu Ser Leu Ser Ile Pro Arg Val Ala Pro
                 635                 640                 645

 Glu His Glu Gly His Tyr Val Cys Glu Val Gln Asp Arg Arg Ser
                 650                 655                 660

 His Asp Lys His Cys His Lys Lys Tyr Leu Ser Val Gln Ala Leu
                 665                 670                 675

 Glu Ala Pro Arg Leu Thr Gln Asn Leu Thr Asp Leu Leu Val Asn
                 680                 685                 690

 Val Ser Asp Ser Leu Glu Met Gln Cys Leu Val Ala Gly Ala His
                 695                 700                 705

 Ala Pro Ser Ile Val Trp Tyr Lys Asp Glu Arg Leu Leu Glu Glu
                 710                 715                 720

 Lys Ser Gly Val Asp Leu Ala Asp Ser Asn Gln Lys Leu Ser Ile
                 725                 730                 735

 Gln Arg Val Arg Glu Glu Asp Ala Gly Pro Tyr Leu Cys Ser Val
                 740                 745                 750

 Cys Arg Pro Lys Gly Cys Val Asn Ser Ser Ala Ser Val Ala Val
                 755                 760                 765

 Glu Gly Ser Glu Asp Lys Gly Ser Met Glu Ile Val Ile Leu Val
                 770                 775                 780

 Gly Thr Gly Val Ile Ala Val Phe Phe Trp Val Leu Leu Leu Leu
                 785                 790                 795

 Ile Phe Cys Asn Met Arg Arg Pro Ala His Ala Asp Ile Lys Thr
                 800                 805                 810

 Gly Tyr Leu Ser Ile Ile Met Asp Pro Gly Glu Val Pro Leu Glu
                 815                 820                 825

 Glu Gln Cys Glu Tyr Leu Ser Tyr Asp Ala Ser Gln Trp Glu Phe
                 830                 835                 840

 Pro Arg Glu Arg Leu His Leu Gly Arg Val Leu Gly Tyr Gly Ala
                 845                 850                 855

 Phe Gly Lys Val Val Glu Ala Ser Ala Phe Gly Ile His Lys Gly
                 860                 865                 870

 Ser Ser Cys Asp Thr Val Ala Val Lys Met Leu Lys Glu Gly Ala
                 875                 880                 885

 Thr Ala Ser Glu Gln Arg Ala Leu Met Ser Glu Leu Lys Ile Leu
                 890                 895                 900

 Ile His Ile Gly Asn His Leu Asn Val Val Asn Leu Leu Gly Ala
                 905                 910                 915

 Cys Thr Lys Pro Gln Gly Pro Leu Met Val Ile Val Glu Phe Cys
                 920                 925                 930

 Lys Tyr Gly Asn Leu Ser Asn Phe Leu Arg Ala Lys Arg Asp Ala
                 935                 940                 945

 Phe Ser Pro Cys Ala Glu Lys Ser Pro Glu Gln Arg Gly Arg Phe
                 950                 955                 960

 Arg Ala Met Val Glu Leu Ala Arg Leu Asp Arg Arg Arg Pro Gly
                 965                 970                 975

 Ser Ser Asp Arg Val Leu Phe Ala Arg Phe Ser Lys Thr Glu Gly
                 980                 985                 990

 Gly Ala Arg Arg Ala Ser Pro Asp Gln Glu Ala Glu Asp Leu Trp
                 995                1000                1005

 Leu Ser Pro Leu Thr Met Glu Asp Leu Val Cys Tyr Ser Phe Gln
                1010                1015                1020

 Val Ala Arg Gly Met Glu Phe Leu Ala Ser Arg Lys Cys Ile His
                1025                1030                1035

 Arg Asp Leu Ala Ala Arg Asn Ile Leu Leu Ser Glu Ser Asp Val
                1040                1045                1050

 Val Lys Ile Cys Asp Phe Gly Leu Ala Arg Asp Ile Tyr Lys Asp
                1055                1060                1065

 Pro Asp Tyr Val Arg Lys Gly Ser Ala Arg Leu Pro Leu Lys Trp
                1070                1075                1080

 Met Ala Pro Glu Ser Ile Phe Asp Lys Val Tyr Thr Thr Gln Ser
                1085                1090                1095

 Asp Val Trp Ser Phe Gly Val Leu Leu Trp Glu Ile Phe Ser Leu
                1100                1105                1110

 Gly Ala Ser Pro Tyr Pro Gly Val Gln Ile Asn Glu Glu Phe Cys
                1115                1120                1125

 Gln Arg Val Arg Asp Gly Thr Arg Met Arg Ala Pro Glu Leu Ala
                1130                1135                1140

 Thr Pro Ala Ile Arg His Ile Met Leu Asn Cys Trp Ser Gly Asp
                1145                1150                1155

 Pro Lys Ala Arg Pro Ala Phe Ser Asp Leu Val Glu Ile Leu Gly
                1160                1165                1170

 Asp Leu Leu Gln Gly Arg Gly Leu Gln Glu Glu Glu Glu Val Cys
                1175                1180                1185

 Met Ala Pro Arg Ser Ser Gln Ser Ser Glu Glu Gly Ser Phe Ser
                1190                1195                1200

 Gln Val Ser Thr Met Ala Leu His Ile Ala Gln Ala Asp Ala Glu
                1205                1210                1215

 Asp Ser Pro Pro Ser Leu Gln Arg His Ser Leu Ala Ala Arg Tyr
                1220                1225                1230

 Tyr Asn Trp Val Ser Phe Pro Gly Cys Leu Ala Arg Gly Ala Glu
                1235                1240                1245

 Thr Arg Gly Ser Ser Arg Met Lys Thr Phe Glu Glu Phe Pro Met
                1250                1255                1260

 Thr Pro Thr Thr Tyr Lys Gly Ser Val Asp Asn Gln Thr Asp Ser
                1265                1270                1275

 Gly Met Val Leu Ala Ser Glu Glu Phe Glu Gln Ile Glu Ser Arg
                1280                1285                1290

 His Arg Gln Glu Ser Gly Phe Arg
                1295

<210> 2216
<211> 988
<212> DNA
<213> Homo sapien

<400> 2216
 aggggacaag tctaggaggt ctctgaggtt actgtaccca tccctccttc 50

 atctccctcc agcatttgtt tctggaagga gtcaacacca acagctctga 100

 cctgggcagc cttcctgaga aaatgcagcc attcctcctc ctgttggcct 150

 ttcttctgac ccctggggct gggacagagg agatcatcgg gggccatgag 200

 gccaagcccc actcccgccc ctacatggcc tttgttcagt ttctgcaaga 250

 gaagagtcgg aagaggtgtg gcggcatcct agtgagaaag gactttgtgc 300

 tgacagctgc tcactgccag ggaagctcca taaatgtcac cttgggggcc 350

 cacaatatca aggaacagga gcggacccag cagtttatcc ctgtgaaaag 400

 acccatcccc catccagcct ataatcctaa gaacttctcc aacgacatca 450

 tgctactgca gctggagaga aaggccaagt ggaccacagc tgtgcggcct 500

 ctcaggctac ctagcagcaa ggcccaggtg aagccagggc agctgtgcag 550

 tgtggctggc tggggttatg tctcaatgag cactttagca accacactgc 600

 aggaagtgtt gctgacagtg cagaaggact gccagtgtga acgtctcttc 650

 catggcaatt acagcagagc cactgagatt tgtgtggggg atccaaagaa 700

 gacacagacc ggtttcaagg gggactccgg ggggcccctc gtgtgtaagg 750

 acgtagccca aggtattctc tcctatggaa acaaaaaagg gacacctcca 800

 ggagtctaca tcaaggtctc acacttcctg ccctggataa agagaacaat 850

 gaagcgcctc taacagcagg catgagacta accttcctct gggcctgacc 900

 atctctggga cagaggcaag aatcccaagg ggtgggcagt cggggttgca 950

 ggactgtaat aaatggatct ctggtgtaaa tatgactg 988

<210> 2217
<211> 246
<212> PRT
<213> Homo sapien

<400> 2217
 Met Gln Pro Phe Leu Leu Leu Leu Ala Phe Leu Leu Thr Pro Gly
   1               5                  10                  15

 Ala Gly Thr Glu Glu Ile Ile Gly Gly His Glu Ala Lys Pro His
                  20                  25                  30

 Ser Arg Pro Tyr Met Ala Phe Val Gln Phe Leu Gln Glu Lys Ser
                  35                  40                  45

 Arg Lys Arg Cys Gly Gly Ile Leu Val Arg Lys Asp Phe Val Leu
                  50                  55                  60

 Thr Ala Ala His Cys Gln Gly Ser Ser Ile Asn Val Thr Leu Gly
                  65                  70                  75

 Ala His Asn Ile Lys Glu Gln Glu Arg Thr Gln Gln Phe Ile Pro
                  80                  85                  90

 Val Lys Arg Pro Ile Pro His Pro Ala Tyr Asn Pro Lys Asn Phe
                  95                 100                 105

 Ser Asn Asp Ile Met Leu Leu Gln Leu Glu Arg Lys Ala Lys Trp
                 110                 115                 120

 Thr Thr Ala Val Arg Pro Leu Arg Leu Pro Ser Ser Lys Ala Gln
                 125                 130                 135

 Val Lys Pro Gly Gln Leu Cys Ser Val Ala Gly Trp Gly Tyr Val
                 140                 145                 150

 Ser Met Ser Thr Leu Ala Thr Thr Leu Gln Glu Val Leu Leu Thr
                 155                 160                 165

 Val Gln Lys Asp Cys Gln Cys Glu Arg Leu Phe His Gly Asn Tyr
                 170                 175                 180

 Ser Arg Ala Thr Glu Ile Cys Val Gly Asp Pro Lys Lys Thr Gln
                 185                 190                 195

 Thr Gly Phe Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Lys Asp
                 200                 205                 210

 Val Ala Gln Gly Ile Leu Ser Tyr Gly Asn Lys Lys Gly Thr Pro
                 215                 220                 225

 Pro Gly Val Tyr Ile Lys Val Ser His Phe Leu Pro Trp Ile Lys
                 230                 235                 240

 Arg Thr Met Lys Arg Leu
                 245

<210> 2218
<211> 1193
<212> DNA
<213> Homo sapien

<400> 2218
 tgaagatcag ctattagaag agaaagatca gttaagtcct ttggacctga 50

 tcagcttgat acaagaacta ctgatttcaa cttctttggc ttaattctct 100

 cggaaacgat gaaatataca agttatatct tggcttttca gctctgcatc 150

 gttttgggtt ctcttggctg ttactgccag gacccatatg taaaagaagc 200

 agaaaacctt aagaaatatt ttaatgcagg tcattcagat gtagcggata 250

 atggaactct tttcttaggc attttgaaga attggaaaga ggagagtgac 300

 agaaaaataa tgcagagcca aattgtctcc ttttacttca aactttttaa 350

 aaactttaaa gatgaccaga gcatccaaaa gagtgtggag accatcaagg 400

 aagacatgaa tgtcaagttt ttcaatagca acaaaaagaa acgagatgac 450

 ttcgaaaagc tgactaatta ttcggtaact gacttgaatg tccaacgcaa 500

 agcaatacat gaactcatcc aagtgatggc tgaactgtcg ccagcagcta 550

 aaacagggaa gcgaaaaagg agtcagatgc tgtttcaagg tcgaagagca 600

 tcccagtaat ggttgtcctg cctgcaatat ttgaatttta aatctaaatc 650

 tatttattaa tatttaacat tatttatatg gggaatatat ttttagactc 700

 atcaatcaaa taagtattta taatagcaac ttttgtgtaa tgaaaatgaa 750

 tatctattaa tatatgtatt atttataatt cctatatcct gtgactgtct 800

 cacttaatcc tttgttttct gactaattag gcaaggctat gtgattacaa 850

 ggctttatct caggggccaa ctaggcagcc aacctaagca agatcccatg 900

 ggttgtgtgt ttatttcact tgatgataca atgaacactt ataagtgaag 950

 tgatactatc cagttactgc cggtttgaaa atatgcctgc aatctgagcc 1000

 agtgctttaa tggcatgtca gacagaactt gaatgtgtca ggtgaccctg 1050

 atgaaaacat agcatctcag gagatttcat gcctggtgct tccaaatatt 1100

 gttgacaact gtgactgtac ccaaatggaa agtaactcat ttgttaaaat 1150

 tatcaatatc taatatatat gaataaagtg taagttcaca act 1193

<210> 2219
<211> 166
<212> PRT
<213> Homo sapien

<400> 2219
 Met Lys Tyr Thr Ser Tyr Ile Leu Ala Phe Gln Leu Cys Ile Val
   1               5                  10                  15

 Leu Gly Ser Leu Gly Cys Tyr Cys Gln Asp Pro Tyr Val Lys Glu
                  20                  25                  30

 Ala Glu Asn Leu Lys Lys Tyr Phe Asn Ala Gly His Ser Asp Val
                  35                  40                  45

 Ala Asp Asn Gly Thr Leu Phe Leu Gly Ile Leu Lys Asn Trp Lys
                  50                  55                  60

 Glu Glu Ser Asp Arg Lys Ile Met Gln Ser Gln Ile Val Ser Phe
                  65                  70                  75

 Tyr Phe Lys Leu Phe Lys Asn Phe Lys Asp Asp Gln Ser Ile Gln
                  80                  85                  90

 Lys Ser Val Glu Thr Ile Lys Glu Asp Met Asn Val Lys Phe Phe
                  95                 100                 105

 Asn Ser Asn Lys Lys Lys Arg Asp Asp Phe Glu Lys Leu Thr Asn
                 110                 115                 120

 Tyr Ser Val Thr Asp Leu Asn Val Gln Arg Lys Ala Ile His Glu
                 125                 130                 135

 Leu Ile Gln Val Met Ala Glu Leu Ser Pro Ala Ala Lys Thr Gly
                 140                 145                 150

 Lys Arg Lys Arg Ser Gln Met Leu Phe Gln Gly Arg Arg Ala Ser
                 155                 160                 165

 Gln


<210> 2220
<211> 1522
<212> DNA
<213> Homo sapien

<400> 2220
 ggcacgaggc tcactgctgt tattgttttc tgacagcatg cctgaaccag 50

 ctaagtcagc tcctgctccg aagaagggtt ccaagaaggc tgtgaccaag 100

 gcgcagaaga aggatggcaa gaagcgcaag cgcagtcgta aggagagcta 150

 ctccgtgtat gtgtacaagg tgctaaaaca ggttcacccc gatactggca 200

 tctcatccaa ggccatgggc atcatgaatt ccttcgttaa cgacatcttc 250

 gaacgcatcg caggcgaggc ttcccgtctg gcccactaca acaagcgctc 300

 gaccattacc tccagggaga tccagaccgc cgtgcgtctg ctgcttcccg 350

 gagagctggc caagcacgca gtgtccgaag gtaccaaggc tgtcaccaag 400

 tatacaagct ccaagtaaat gtgtgcttag gtgctttaaa actcaaaggc 450

 tcttttcaga gccactcaag tctcacataa agagctttaa tattgaattt 500

 caccgttttc tagggaataa tttttccgat tttgtaatcc cagcactttg 550

 ggaggccgag gcgtgcggat cgagaccagt ttggctaacg tggttaaatc 600

 tcgtttctac taaaaataca aatattagcc gggcgtgggg cagtcgcgtg 650

 tcatcccaga gactcgggag gctgccgcag gagaatcact taaacccagc 700

 aagcaaaggt tgcagtgaaa agacatggcg cttttgcatt ctagcctggg 750

 cgacaaaggc gaggcttcgt ctcaaaaaaa attgatcagg agatactcct 800

 gttctgtgtt ggcaagatcc tgtaatccta gcactttggg aggtcgatgc 850

 atgaggcttt cttcagctca ggagttaaca gatttgcctg ggcaacatag 900

 aactcgtctc tgcaaaaaaa tgaagctaac caggtgtgac ggcttgcgtc 950

 tgtactatca tttactcggt aggctgaggt ggtaggatag cttaaactct 1000

 cgggctagag actgcaggaa catgtgaata cgctagtgca attccagcct 1050

 gggcaacact ggaaagggta ggaagagtag tctttgggtc cctaaagatc 1100

 acctgataac aagtttgact tttctgagca ctcttgtgga gtttgttgtg 1150

 gagggaatac catgggcatt ggcaatgtaa agttgatcta aaaaatctcg 1200

 ttttccgccg tgcgcggtgg ctcacgcctc taatcccatc actttgggag 1250

 gccgagacgg gcggatcacg aggtcaggag gtcgagacca tcctggctaa 1300

 cactgtgaaa ccctgtctct actaaaaaaa tacaaacaaa attagccggg 1350

 cgtggtggca ctcacctgta gtttcagcta ctctggaagc tgaggctgga 1400

 gagtcacttg aacccgggag gcggaggttg cagtgatcag agatcgcgcc 1450

 actgcactcc atcctgggcg aaagagctag attccatctc ataaaaaaaa 1500

 aaaaaaaaaa aaaaaaaaaa aa 1522

<210> 2221
<211> 126
<212> PRT
<213> Homo sapien

<400> 2221
 Met Pro Glu Pro Ala Lys Ser Ala Pro Ala Pro Lys Lys Gly Ser
   1               5                  10                  15

 Lys Lys Ala Val Thr Lys Ala Gln Lys Lys Asp Gly Lys Lys Arg
                  20                  25                  30

 Lys Arg Ser Arg Lys Glu Ser Tyr Ser Val Tyr Val Tyr Lys Val
                  35                  40                  45

 Leu Lys Gln Val His Pro Asp Thr Gly Ile Ser Ser Lys Ala Met
                  50                  55                  60

 Gly Ile Met Asn Ser Phe Val Asn Asp Ile Phe Glu Arg Ile Ala
                  65                  70                  75

 Gly Glu Ala Ser Arg Leu Ala His Tyr Asn Lys Arg Ser Thr Ile
                  80                  85                  90

 Thr Ser Arg Glu Ile Gln Thr Ala Val Arg Leu Leu Leu Pro Gly
                  95                 100                 105

 Glu Leu Ala Lys His Ala Val Ser Glu Gly Thr Lys Ala Val Thr
                 110                 115                 120

 Lys Tyr Thr Ser Ser Lys
                 125

<210> 2222
<211> 4371
<212> DNA
<213> Homo sapien

<400> 2222
 gggtggatta attttttttt tttgacgttc ttagaacagt gcctgactta 50

 attctacttc atagggttga tgtaattttg agacttaaat aagttgatac 100

 taaaatacca cttagtgtcc cgaacactgt ttgacatttt agtatcaacc 150

 aagtctcaag gttacttcaa tcctgtgaac tagagccaag gcacctccag 200

 tggcctttca gaagttccat ttccactccc gcctcatctc ctaattctat 250

 ctccccgttc tctttactcg agccctcctg gccttgccct tccttaggcc 300

 tgatacgcac ctatctgaag acctttgcac tgcactccag cctggaaggc 350

 agagagagac tccgtttcaa aaaagaaaag aattctgggt ttgaatcctg 400

 cctctccgtc tgctagggat atgatttagg gcaagttgct tgagctcttt 450

 gggcctctgt tttcacgtct gtatgataga ggtggtattg tttgacttgt 500

 atttgtgaag tttcaatgag attgataatt gtcgatttta tgttaatccc 550

 tagtacatgg cctgctgtca acacccagga cacccaggat atggtctttg 600

 ctgtttgatt ttcctcatcc ccagtctcaa ggggaagcca ggacaatgag 650

 aacagccact tcccatcagg agtcactgca aggcccccag ggtgggatgg 700

 tggggagata agaaccgtga gagaagttgg cacaaaggag ttatgggaca 750

 aagggtccaa gataggcaga aaagaaaatg ttgccagttg atggggaaga 800

 aaggaagtcg gagggctcag acactgaggg ggacagaaca tctccatgtg 850

 cagtctcatc tcttatagtc agcaacaggt atccacgggg agggccctac 900

 atcatctgct accctgaagg atctggaggt aggaggctct gggcggaggt 950

 gcagtgaccc cgcaggccag ccctccaacc tcctcccgca gcggggactg 1000

 ggtgcccctc tgccagctga gacagcccac acacaaccca gccctaatga 1050

 tcgttctctc tacctctccc ccaagtcctc ctccgcctcc tcctctctgc 1100

 atgcgcctca gagcccgtgc caagaacaag cagcagtcct gaactcgagg 1150

 tccataaaaa tcagtcgact gaatgacacc atcaaatctt tgaaacaaca 1200

 gaagaaacaa gtggaacatc agctggaaga agaaaagaaa gcaaacaatg 1250

 agaaacagaa agctgaaagg gagctagagg gtcaaatcca gagattgaac 1300

 acagagaaaa agaaactaaa tacggacctg tatcacatga aacattctct 1350

 cagatacttt gaagaagagt ccaaggatct ggccggccgc ctgcaacgtt 1400

 catcgcagcg tataggagag ttagagtggt ctctctgtgc tgtcgccgcc 1450

 acacagaaga agaagccgga tgggttctcg agccgcagta aagcacttct 1500

 caagcggcag ttagagcagt ccatacggga gcagatactg ctgaaaggac 1550

 acgtgacaca gttgaaggag tcgcttaaag aagtccagct ggagagagat 1600

 caatatgctg aacaaataaa aggagagagg gcccagtggc agcagaggat 1650

 gaggaaaatg tcgcaggagg tttgcacatt gaaggaggag aagaagcatg 1700

 atacgcatcg ggtagaggag ctggagagga gcttgtccag actcaaaaac 1750

 cagatggctg agccactgcc cccggatgcc ccagcagtgt cctctgaggt 1800

 ggagctgcaa gacctgagga aggagctgga gagagtggca ggagagctcc 1850

 aggctcaggt ggaaaacaat cagtgcatca gtctcctgaa ccgtgggcaa 1900

 aaggagaggc ttcgcgagca ggaggagagg cttcaggagc agcaggagag 1950

 gcttcgggaa caggagaaga ggcttcagca gctgtccgag ccacagagcg 2000

 acttggagga gctgcacgag aacaagagcg cactgcagtt ggagcagcaa 2050

 gtaaaggagc tgcaggagaa gctgggccag gtgacggaga cgctcacctc 2100

 ggctgagaag gagccagagg cagcagtccc agcctcaggg actgggggcg 2150

 agtctagcgg ccttatggac ctcctggagg agaaggtgga cctgagggag 2200

 catgtggaga aactggaact tggattcatc cagtaccgga gagagagatg 2250

 ccatcagaaa gtacatcgcc ttctaacaga gccaggggac agtgccaaag 2300

 atgcgtcacc gggaggaggc catcatcagg ctggcccagg acgaggagga 2350

 gaggaaggtg aagctgttgg agctgcagga gatggtgttg cggcttgtgg 2400

 cagctatagc gaggggcacg gcaaattcct ggccgctgcc cggaaccctg 2450

 ctgctgaacc cagtccagga gccccagccc cccaggagct cggggctgcc 2500

 gacaagcatg gtgatctttg tgaggcgagc ctcaccaaca gcgtggagcc 2550

 tgcacaagga gaagccaggg agggttcttc ccaggacaac cctactgcac 2600

 agccagtcgt gcagctcctt ggtgagatgc aggaccacca ggagcaccca 2650

 ggcttgggca gcaactgctg tgtgccatgc ttttgctggg cttggctgcc 2700

 gagaagaagg agataaacac caccatcatc aaagagctgc tcaagaaatt 2750

 tttaaaaacg aaacaaagtt atggggttaa tctcctacac aattcattta 2800

 cttcatttga atgttagagc tactcatgat tatttgtgtt tctaatttat 2850

 agtttaagtt tatttgtaaa aagttaaaag agagtgggtc tctgtgcctc 2900

 tcactgatgt tcactctggc atcctttagc atttttcttt tttcatttca 2950

 taattgtagg tcattagcat gcatatcgag tttgccctta cgtggtggga 3000

 gttcaaacac acaaagaccc actctttgca caaaactgtt ctcgctggtt 3050

 tggaataggc tcccgtgctt ttttaatgtt attgcagcat ggatgttcat 3100

 tacagaattc agataaaatt tgctaatgtt ctgctatgat gtttgatctc 3150

 atcttaatca cagtgagctc ttccatagct caatatgcgg tttgccctca 3200

 agtgtgcact gtttattact ttgtaatatg ccactatgag tactgacact 3250

 tagagctgtt taaaggccga gaactggaaa cagcctttcc tccattttct 3300

 gtgtattggt gatgggagtg ataacctttt gggggagctt tctaaatctc 3350

 gcagaagagg aaagtggcct gctctggcag gtatgtgcag gatacagtgt 3400

 gtttcatctg ttccggtgcc aagaatgagc actgtactgt ggcagttccc 3450

 tttggatttg tatgtgctct gggctcatga agatattgca tcgtgagctg 3500

 cagcagttgc actctttttc agtgacctaa aaatggctta tttccgagga 3550

 atgaaaggct gccatcgttg gctgtggatg tggaaaacct ttcctagctt 3600

 agagcatttg tatctacaat acattttaaa gtcagagttc gtgttccctg 3650

 ttttaatcac atgactacct gtgccagtac acgaaagggc gctggttggc 3700

 attcttctta atgtatttag taaagatcat aagacatcct ttaagagttt 3750

 aaatgtctct gaaacaggca tacaggctct agtcaagaat gaattagagt 3800

 gaaggaaagc tgtgtgacac ctggcattcc tctctgttca tggagcttct 3850

 ttgaggcttg aagtttgatt ttactatcta gacctctctg gctaatacct 3900

 attctccaac cacctcggtt actctgacat aggaatttac ttcttttcct 3950

 tgagtggaaa acactttaga aaataataac aaacattatt ataaactaat 4000

 atatgtgaga gtacttagtt gaaacaaaaa ggaattttag tagacagtat 4050

 tatattatct ttgaaaatca aggagaagtt tatgcaactg aaaatgttta 4100

 cacactgtgc tgcaatctac tgtttgtgaa tgtcaatgta ttatcaggaa 4150

 acatggctat acgatcgcag agttgtattt cctcacaaac ttctttacga 4200

 agagtgaaat atgtttttgt acctctcagt ttcagtcagg gacatatttt 4250

 gtgcaatatt tctgtgattg tgcctatgcg tgatgagtga atgcatttca 4300

 atcatacatt gcctaaatca taacttgatg atgcttggga aagaatcaac 4350

 agttaaaact tcatgaagtt c 4371

<210> 2223
<211> 459
<212> PRT
<213> Homo sapien

<400> 2223
 Met Lys His Ser Leu Arg Tyr Phe Glu Glu Glu Ser Lys Asp Leu
   1               5                  10                  15

 Ala Gly Arg Leu Gln Arg Ser Ser Gln Arg Ile Gly Glu Leu Glu
                  20                  25                  30

 Trp Ser Leu Cys Ala Val Ala Ala Thr Gln Lys Lys Lys Pro Asp
                  35                  40                  45

 Gly Phe Ser Ser Arg Ser Lys Ala Leu Leu Lys Arg Gln Leu Glu
                  50                  55                  60

 Gln Ser Ile Arg Glu Gln Ile Leu Leu Lys Gly His Val Thr Gln
                  65                  70                  75

 Leu Lys Glu Ser Leu Lys Glu Val Gln Leu Glu Arg Asp Gln Tyr
                  80                  85                  90

 Ala Glu Gln Ile Lys Gly Glu Arg Ala Gln Trp Gln Gln Arg Met
                  95                 100                 105

 Arg Lys Met Ser Gln Glu Val Cys Thr Leu Lys Glu Glu Lys Lys
                 110                 115                 120

 His Asp Thr His Arg Val Glu Glu Leu Glu Arg Ser Leu Ser Arg
                 125                 130                 135

 Leu Lys Asn Gln Met Ala Glu Pro Leu Pro Pro Asp Ala Pro Ala
                 140                 145                 150

 Val Ser Ser Glu Val Glu Leu Gln Asp Leu Arg Lys Glu Leu Glu
                 155                 160                 165

 Arg Val Ala Gly Glu Leu Gln Ala Gln Val Glu Asn Asn Gln Cys
                 170                 175                 180

 Ile Ser Leu Leu Asn Arg Gly Gln Lys Glu Arg Leu Arg Glu Gln
                 185                 190                 195

 Glu Glu Arg Leu Gln Glu Gln Gln Glu Arg Leu Arg Glu Gln Glu
                 200                 205                 210

 Lys Arg Leu Gln Gln Leu Ser Glu Pro Gln Ser Asp Leu Glu Glu
                 215                 220                 225

 Leu His Glu Asn Lys Ser Ala Leu Gln Leu Glu Gln Gln Val Lys
                 230                 235                 240

 Glu Leu Gln Glu Lys Leu Gly Gln Val Thr Glu Thr Leu Thr Ser
                 245                 250                 255

 Ala Glu Lys Glu Pro Glu Ala Ala Val Pro Ala Ser Gly Thr Gly
                 260                 265                 270

 Gly Glu Ser Ser Gly Leu Met Asp Leu Leu Glu Glu Lys Val Asp
                 275                 280                 285

 Leu Arg Glu His Val Glu Lys Leu Glu Leu Gly Phe Ile Gln Tyr
                 290                 295                 300

 Arg Arg Glu Arg Cys His Gln Lys Val His Arg Leu Leu Thr Glu
                 305                 310                 315

 Pro Gly Asp Ser Ala Lys Asp Ala Ser Pro Gly Gly Gly His His
                 320                 325                 330

 Gln Ala Gly Pro Gly Arg Gly Gly Glu Glu Gly Glu Ala Val Gly
                 335                 340                 345

 Ala Ala Gly Asp Gly Val Ala Ala Cys Gly Ser Tyr Ser Glu Gly
                 350                 355                 360

 His Gly Lys Phe Leu Ala Ala Ala Arg Asn Pro Ala Ala Glu Pro
                 365                 370                 375

 Ser Pro Gly Ala Pro Ala Pro Gln Glu Leu Gly Ala Ala Asp Lys
                 380                 385                 390

 His Gly Asp Leu Cys Glu Ala Ser Leu Thr Asn Ser Val Glu Pro
                 395                 400                 405

 Ala Gln Gly Glu Ala Arg Glu Gly Ser Ser Gln Asp Asn Pro Thr
                 410                 415                 420

 Ala Gln Pro Val Val Gln Leu Leu Gly Glu Met Gln Asp His Gln
                 425                 430                 435

 Glu His Pro Gly Leu Gly Ser Asn Cys Cys Val Pro Cys Phe Cys
                 440                 445                 450

 Trp Ala Trp Leu Pro Arg Arg Arg Arg
                 455

<210> 2224
<211> 2020
<212> DNA
<213> Homo sapien

<400> 2224
 gcagattcac agggcctctg agcattatcc cccatactcc tccccatcat 50

 tctccaccca gctgttggag ccatctgtct gatcaccttg gactccatag 100

 tacactgggg caaagcacag ccccagtttc tggaggcaga tgggtaacca 150

 ggaaaaggca tgaatgaggg ggccccagga gacagtgact tagagactga 200

 ggcaagagtg ccgtggtcaa tcatgggtca ttgtcttcga actggacagg 250

 ccagaatgtc tgccacaccc acacctgcag gtgaaggagc cagaagggat 300

 gaactttttg ggattctcca aatactccat cagtgtatcc tgtcttcagg 350

 tgatgctttt gttcttactg gcgtctgttg ttcctggagg cagaatggca 400

 agccaccata ttcacaaaag gaagataagg aagtacaaac tggatacatg 450

 aatgctcaaa ttgaaattat tccatgcaag atctgtggag acaaatcatc 500

 aggaatccat tatggtgtca ttacatgtga aggctgcaag ggctttttca 550

 ggagaagtca gcaaagcaat gccacctact cctgtcctcg tcagaagaac 600

 tgtttgattg atcgaaccag tagaaaccgc tgccaacact gtcgattaca 650

 gaaatgcctt gccgtaggga tgtctcgaga tgctgtaaaa tttggccgaa 700

 tgtcaaaaaa gcagagagac agcttgtatg cagaagtaca gaaacaccgg 750

 atgcagcagc agcagcgcga ccaccagcag cagcctggag aggctgagcc 800

 gctgacgccc acctacaaca tctcggccaa cgggctgacg gaacttcacg 850

 acgacctcag taactacatt gacgggcaca cccctgaggg gagtaaggca 900

 gactccgccg tcagcagctt ctacctggac atacagcctt ccccagacca 950

 gtcaggtctt gatatcaatg gaatcaaacc agaaccaata tgtgactaca 1000

 caccagcatc aggcttcttt ccctactgtt cgttcaccaa cggcgagact 1050

 tccccaactg tgtccatggc agaattagaa caccttgcac agaatatatc 1100

 taaatcgcat ctggaaacct gccaatactt gagagaagag ctccagcaga 1150

 taacgtggca gaccttttta caggaagaaa ttgagaacta tcaaaacaag 1200

 cagcgggagg tgatgtggca attgtgtgcc atcaaaatta cagaagctat 1250

 acagtatgtg gtggagtttg ccaaacgcat tgatggattt atggaactgt 1300

 gtcaaaatga tcaaattgtg cttctaaaag caggttctct agaggtggtg 1350

 tttatcagaa tgtgccgtgc ctttgactct cagaacaaca ccgtgtactt 1400

 tgatgggaag tatgccagcc ccgacgtctt caaatcctta ggttgtgaag 1450

 actttattag ctttgtgttt gaatttggaa agagtttatg ttctatgcac 1500

 ctgactgaag atgaaattgc attattttct gcatttgtac tgatgtcagc 1550

 agatcgctca tggctgcaag aaaaggtaaa aattgaaaaa ctgcaacaga 1600

 aaattcagct agctcttcaa cacgtcctac agaagaatca ccgagaagat 1650

 ggaatactaa caaagttaat atgcaaggtg tctacattaa gagccttatg 1700

 tggacgacat acagaaaagc taatggcatt taaagcaata tacccagaca 1750

 ttgtgcgact tcattttcct ccattataca aggagttgtt cacttcagaa 1800

 tttgagccag caatgcaaat tgatgggtaa atgttatcac ctaagcactt 1850

 ctagaatgtc tgaagtacaa acatgaaaaa caaacaaaaa aattaaccga 1900

 gacactttat atggccctgc acagacctgg agcgccacac actgcacatc 1950

 ttttggtgat cggggtcagg caaaggaggg gaaacaatga aaacaaataa 2000

 agttgaactt gtttttctca 2020

<210> 2225
<211> 556
<212> PRT
<213> Homo sapien

<400> 2225
 Met Asn Glu Gly Ala Pro Gly Asp Ser Asp Leu Glu Thr Glu Ala
   1               5                  10                  15

 Arg Val Pro Trp Ser Ile Met Gly His Cys Leu Arg Thr Gly Gln
                  20                  25                  30

 Ala Arg Met Ser Ala Thr Pro Thr Pro Ala Gly Glu Gly Ala Arg
                  35                  40                  45

 Arg Asp Glu Leu Phe Gly Ile Leu Gln Ile Leu His Gln Cys Ile
                  50                  55                  60

 Leu Ser Ser Gly Asp Ala Phe Val Leu Thr Gly Val Cys Cys Ser
                  65                  70                  75

 Trp Arg Gln Asn Gly Lys Pro Pro Tyr Ser Gln Lys Glu Asp Lys
                  80                  85                  90

 Glu Val Gln Thr Gly Tyr Met Asn Ala Gln Ile Glu Ile Ile Pro
                  95                 100                 105

 Cys Lys Ile Cys Gly Asp Lys Ser Ser Gly Ile His Tyr Gly Val
                 110                 115                 120

 Ile Thr Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Ser Gln Gln
                 125                 130                 135

 Ser Asn Ala Thr Tyr Ser Cys Pro Arg Gln Lys Asn Cys Leu Ile
                 140                 145                 150

 Asp Arg Thr Ser Arg Asn Arg Cys Gln His Cys Arg Leu Gln Lys
                 155                 160                 165

 Cys Leu Ala Val Gly Met Ser Arg Asp Ala Val Lys Phe Gly Arg
                 170                 175                 180

 Met Ser Lys Lys Gln Arg Asp Ser Leu Tyr Ala Glu Val Gln Lys
                 185                 190                 195

 His Arg Met Gln Gln Gln Gln Arg Asp His Gln Gln Gln Pro Gly
                 200                 205                 210

 Glu Ala Glu Pro Leu Thr Pro Thr Tyr Asn Ile Ser Ala Asn Gly
                 215                 220                 225

 Leu Thr Glu Leu His Asp Asp Leu Ser Asn Tyr Ile Asp Gly His
                 230                 235                 240

 Thr Pro Glu Gly Ser Lys Ala Asp Ser Ala Val Ser Ser Phe Tyr
                 245                 250                 255

 Leu Asp Ile Gln Pro Ser Pro Asp Gln Ser Gly Leu Asp Ile Asn
                 260                 265                 270

 Gly Ile Lys Pro Glu Pro Ile Cys Asp Tyr Thr Pro Ala Ser Gly
                 275                 280                 285

 Phe Phe Pro Tyr Cys Ser Phe Thr Asn Gly Glu Thr Ser Pro Thr
                 290                 295                 300

 Val Ser Met Ala Glu Leu Glu His Leu Ala Gln Asn Ile Ser Lys
                 305                 310                 315

 Ser His Leu Glu Thr Cys Gln Tyr Leu Arg Glu Glu Leu Gln Gln
                 320                 325                 330

 Ile Thr Trp Gln Thr Phe Leu Gln Glu Glu Ile Glu Asn Tyr Gln
                 335                 340                 345

 Asn Lys Gln Arg Glu Val Met Trp Gln Leu Cys Ala Ile Lys Ile
                 350                 355                 360

 Thr Glu Ala Ile Gln Tyr Val Val Glu Phe Ala Lys Arg Ile Asp
                 365                 370                 375

 Gly Phe Met Glu Leu Cys Gln Asn Asp Gln Ile Val Leu Leu Lys
                 380                 385                 390

 Ala Gly Ser Leu Glu Val Val Phe Ile Arg Met Cys Arg Ala Phe
                 395                 400                 405

 Asp Ser Gln Asn Asn Thr Val Tyr Phe Asp Gly Lys Tyr Ala Ser
                 410                 415                 420

 Pro Asp Val Phe Lys Ser Leu Gly Cys Glu Asp Phe Ile Ser Phe
                 425                 430                 435

 Val Phe Glu Phe Gly Lys Ser Leu Cys Ser Met His Leu Thr Glu
                 440                 445                 450

 Asp Glu Ile Ala Leu Phe Ser Ala Phe Val Leu Met Ser Ala Asp
                 455                 460                 465

 Arg Ser Trp Leu Gln Glu Lys Val Lys Ile Glu Lys Leu Gln Gln
                 470                 475                 480

 Lys Ile Gln Leu Ala Leu Gln His Val Leu Gln Lys Asn His Arg
                 485                 490                 495

 Glu Asp Gly Ile Leu Thr Lys Leu Ile Cys Lys Val Ser Thr Leu
                 500                 505                 510

 Arg Ala Leu Cys Gly Arg His Thr Glu Lys Leu Met Ala Phe Lys
                 515                 520                 525

 Ala Ile Tyr Pro Asp Ile Val Arg Leu His Phe Pro Pro Leu Tyr
                 530                 535                 540

 Lys Glu Leu Phe Thr Ser Glu Phe Glu Pro Ala Met Gln Ile Asp
                 545                 550                 555

 Gly


<210> 2226
<211> 2610
<212> DNA
<213> Homo sapien

<400> 2226
 ggactgttaa ctgtttctgg caaacatgaa gtcaggcctc tggtatttct 50

 ttctcttctg cttgcgcatt aaagttttaa caggagaaat caatggttct 100

 gccaattatg agatgtttat atttcacaac ggaggtgtac aaattttatg 150

 caaatatcct gacattgtcc agcaatttaa aatgcagttg ctgaaagggg 200

 ggcaaatact ctgcgatctc actaagacaa aaggaagtgg aaacacagtg 250

 tccattaaga gtctgaaatt ctgccattct cagttatcca acaacagtgt 300

 ctcttttttt ctatacaact tggaccattc tcatgccaac tattacttct 350

 gcaacctatc aatttttgat cctcctcctt ttaaagtaac tcttacagga 400

 ggatatttgc atatttatga atcacaactt tgttgccagc tgaagttctg 450

 gttacccata ggatgtgcag cctttgttgt agtctgcatt ttgggatgca 500

 tacttatttg ttggcttaca aaaaagaagt attcatccag tgtgcacgac 550

 cctaacggtg aatacatgtt catgagagca gtgaacacag ccaaaaaatc 600

 tagactcaca gatgtgaccc tataatatgg aactctggca cccaggcatg 650

 aagcacgttg gccagttttc ctcaacttga agtgcaagat tctcttattt 700

 ccgggaccac ggagagtctg acttaactac atacatcttc tgctggtgtt 750

 ttgttcaatc tggaagaatg actgtatcag tcaatgggga ttttaacaga 800

 ctgccttggt actgccgagt cctctcaaaa caaacaccct cttgcaacca 850

 gctttggaga aagcccagct cctgtgtgct cactgggagt ggaatccctg 900

 tctccacatc tgctcctagc agtgcatcag ccagtaaaac aaacacattt 950

 acaagaaaaa tgttttaaag atgccagggg tactgaatct gcaaagcaaa 1000

 tgagcagcca aggaccagca tctgtccgca tttcactatc atactacctc 1050

 ttctttctgt agggatgaga attcctcttt taatcagtca agggagatgc 1100

 ttcaaagctg gagctatttt atttctgaga tgttgatgtg aactgtacat 1150

 tagtacatac tcagtactct ccttcaattg ctgaacccca gttgaccatt 1200

 ttaccaagac tttagatgct ttcttgtgcc ctcaattttc tttttaaaaa 1250

 tacttctaca tgactgcttg acagcccaac agccactctc aatagagagc 1300

 tatgtcttac attctttcct ctgctgctca atagttttat atatctatgc 1350

 atacatatat acacacatat gtatataaaa ttcataatga atatatttgc 1400

 ctatattctc cctacaagaa tatttttgct ccagaaagac atgttctttt 1450

 ctcaaattca gttaaaatgg tttactttgt tcaagttagt ggtaggaaac 1500

 attgcccgga attgaaagca aatttatttt attatcctat tttctaccat 1550

 tatctatgtt ttcatggtgc tattaattac aagtttagtt ctttttgtag 1600

 atcatattaa aattgcaaac aaaatcatct ttaatgggcc agcattctca 1650

 tggggtagag cagaatattc atttagcctg aaagctgcag ttactatagg 1700

 ttgctgtcag actataccca tggtgcctct gggcttgaca ggtcaaaatg 1750

 gtccccatca gcctggagca gccctccaga cctgggtgga attccagggt 1800

 tgagagactc ccctgagcca gaggccacta ggtattcttg ctcccagagg 1850

 ctgaagtcac cctgggaatc acagtggtct acctgcattc ataattccag 1900

 gatctgtgaa gagcacatat gtgtcagggc acaattccct ctcataaaaa 1950

 ccacacagcc tggaaattgg ccctggccct tcaagatagc cttctttaga 2000

 atatgatttg gctagaaaga ttcttaaata tgtggaatat gattattctt 2050

 agctggaata ttttctctac ttcctgtctg catgcccaag gcttctgaag 2100

 cagccaatgt cgatgcaaca acatttgtaa ctttaggtaa actgggatta 2150

 tgttgtagtt taacattttg taactgtgtg cttatagttt acaagtgaga 2200

 cccgatatgt cattatgcat acttatatta tcttaagcat gtgtaatgct 2250

 ggatgtgtac agtacagtac ttaacttgta atttgaatct agtatggtgt 2300

 tctgttttca gctgacttgg acaacctgac tggctttgca caggtgttcc 2350

 ctgagttgtt tgcaggtttc tgtgtgtggg gtggggtatg gggaggagaa 2400

 ccttcatggt ggcccacctg gcctggttgt ccaagctgtg cctcgacaca 2450

 tcctcatccc aagcatggga cacctcaaga tgaataataa ttcacaaaat 2500

 ttctgtgaaa tcaaatccag ttttaagagg agccacttat caaagagatt 2550

 ttaacagtag taagaaggca aagaataaac atttgatatt cagcaactga 2600

 aaaaaaaaaa 2610

<210> 2227
<211> 199
<212> PRT
<213> Homo sapien

<400> 2227
 Met Lys Ser Gly Leu Trp Tyr Phe Phe Leu Phe Cys Leu Arg Ile
   1               5                  10                  15

 Lys Val Leu Thr Gly Glu Ile Asn Gly Ser Ala Asn Tyr Glu Met
                  20                  25                  30

 Phe Ile Phe His Asn Gly Gly Val Gln Ile Leu Cys Lys Tyr Pro
                  35                  40                  45

 Asp Ile Val Gln Gln Phe Lys Met Gln Leu Leu Lys Gly Gly Gln
                  50                  55                  60

 Ile Leu Cys Asp Leu Thr Lys Thr Lys Gly Ser Gly Asn Thr Val
                  65                  70                  75

 Ser Ile Lys Ser Leu Lys Phe Cys His Ser Gln Leu Ser Asn Asn
                  80                  85                  90

 Ser Val Ser Phe Phe Leu Tyr Asn Leu Asp His Ser His Ala Asn
                  95                 100                 105

 Tyr Tyr Phe Cys Asn Leu Ser Ile Phe Asp Pro Pro Pro Phe Lys
                 110                 115                 120

 Val Thr Leu Thr Gly Gly Tyr Leu His Ile Tyr Glu Ser Gln Leu
                 125                 130                 135

 Cys Cys Gln Leu Lys Phe Trp Leu Pro Ile Gly Cys Ala Ala Phe
                 140                 145                 150

 Val Val Val Cys Ile Leu Gly Cys Ile Leu Ile Cys Trp Leu Thr
                 155                 160                 165

 Lys Lys Lys Tyr Ser Ser Ser Val His Asp Pro Asn Gly Glu Tyr
                 170                 175                 180

 Met Phe Met Arg Ala Val Asn Thr Ala Lys Lys Ser Arg Leu Thr
                 185                 190                 195

 Asp Val Thr Leu


<210> 2228
<211> 2206
<212> DNA
<213> Homo sapien

<400> 2228
 ggaggaggag gaggaggagg aagaagaggt agcggcaagg tcgcggtctg 50

 aggttccggt gctcgccgcc gcccagctcc cagccgaggc tttctcaacc 100

 gcgtcaataa aaggccgccc cgacccgccc ccgcgccccg cagccctgcc 150

 ggacaccccg ggctgcagct gagcgggcgc agacgggccg aggcgggcgc 200

 cgggcgcgca gggaccgagg gaccgagtgc tccccatgag cgcacgtggg 250

 ccgggcggtc cgcaagcccg gctgagagcg cgccatgggg caggcgggct 300

 gcaaggggct ctgcctgtcg ctgttcgact acaagaccga gaagtatgtc 350

 atcgccaaga acaagaaggt gggcctgctg taccggctgc tgcaggcctc 400

 catcctggcg tacctggtcg tatgggtgtt cctgataaag aagggttacc 450

 aagacgtcga cacctccctg cagagtgctg tcatcaccaa agtcaagggc 500

 gtggccttca ccaacacctc ggatcttggg cagcggatct gggatgtcgc 550

 cgactacgtc attccagccc agggagagaa cgtctttttt gtggtcacca 600

 acctgattgt gacccccaac cagcggcaga acgtctgtgc tgagaatgaa 650

 ggcattcctg atggcgcgtg ctccaaggac agcgactgcc acgctgggga 700

 agcggttaca gctggaaacg gagtgaagac cggccgctgc ctgcggagag 750

 agaacttggc caggggcacc tgtgagatct ttgcctggtg cccgttggag 800

 acaagctcca ggccggagga gccattcctg aaggaggccg aagacttcac 850

 cattttcata aagaaccaca tccgtttccc caaattcaac ttctccaaaa 900

 gcaatgtgat ggacgtcaag gacagatctt tcctgaaatc atgccacttt 950

 ggccccaaga accactactg ccccatcttc cgactgggct ccgtgatccg 1000

 ctgggccggg agcgacttcc aggatatagc cctggagggt ggcgtgatag 1050

 gaattaatat tgaatggaac tgtgatcttg ataaagctgc ctctgagtgc 1100

 caccctcact attcttttag ccgtctggac aataaacttt caaagtctgt 1150

 ctcctccggg tacaacttca gatttgccag atattaccga gacgcagccg 1200

 gggtggagtt ccgcaccctg atgaaagcct acgggatccg ctttgacgtg 1250

 atggtgaacg gcaagggtgc tttcttctgc gacctggtac tcatctacct 1300

 catcaaaaag agagagtttt accgtgacaa gaagtacgag gaagtgaggg 1350

 gcctagaaga cagttcccag gaggccgagg acgaggcatc ggggctgggg 1400

 ctatctgagc agctcacatc tgggccaggg ctgctgggga tgccggagca 1450

 gcaggagctg caggagccac ccgaggcgaa gcgtggaagc agcagtcaga 1500

 aggggaacgg atctgtgtgc ccacagctcc tggagcccca caggagcacg 1550

 tgaattgcct ctgcttacgt tcaggccctg tcctaaaccc agccgtctag 1600

 cacccagtga tcccatgcct ttgggaatcc caggatgctg cccaacggga 1650

 aatttgtaca ttgggtgcta tcaatgccac atcacaggga ccagccatca 1700

 cagagcaaag tgacctccac gtctgatgct ggggtcatca ggacggaccc 1750

 atcatggctg tctttttgcc ccaccccctg ccgtcagttc ttcctttctc 1800

 cgtggctggc ttcccgcact agggaacggg ttgtaaatgg ggaacatgac 1850

 ttccttccgg agtccttgag cacctcagct aaggaccgca gtgccctgta 1900

 gagttcctag attacctcac tgggaatagc attgtgcgtg tccggaaaag 1950

 ggctccattt ggttccagcc cactcccctc tgcaagtgcc gcagcttccc 2000

 tcagagcata ctctccagtg gatccaagta ctctctctcc taaagacacc 2050

 accttcctgc cagctgtttg cccttaggcc agtacacaga attaaagtgg 2100

 gggagatggc agacgctttc tgggacctgc ccaagatatg tattctctga 2150

 cactcttatt tggtcataaa acaataaatg gtgtcaattt caaaaaaaaa 2200

 aaaaaa 2206

<210> 2229
<211> 422
<212> PRT
<213> Homo sapien

<400> 2229
 Met Gly Gln Ala Gly Cys Lys Gly Leu Cys Leu Ser Leu Phe Asp
   1               5                  10                  15

 Tyr Lys Thr Glu Lys Tyr Val Ile Ala Lys Asn Lys Lys Val Gly
                  20                  25                  30

 Leu Leu Tyr Arg Leu Leu Gln Ala Ser Ile Leu Ala Tyr Leu Val
                  35                  40                  45

 Val Trp Val Phe Leu Ile Lys Lys Gly Tyr Gln Asp Val Asp Thr
                  50                  55                  60

 Ser Leu Gln Ser Ala Val Ile Thr Lys Val Lys Gly Val Ala Phe
                  65                  70                  75

 Thr Asn Thr Ser Asp Leu Gly Gln Arg Ile Trp Asp Val Ala Asp
                  80                  85                  90

 Tyr Val Ile Pro Ala Gln Gly Glu Asn Val Phe Phe Val Val Thr
                  95                 100                 105

 Asn Leu Ile Val Thr Pro Asn Gln Arg Gln Asn Val Cys Ala Glu
                 110                 115                 120

 Asn Glu Gly Ile Pro Asp Gly Ala Cys Ser Lys Asp Ser Asp Cys
                 125                 130                 135

 His Ala Gly Glu Ala Val Thr Ala Gly Asn Gly Val Lys Thr Gly
                 140                 145                 150

 Arg Cys Leu Arg Arg Glu Asn Leu Ala Arg Gly Thr Cys Glu Ile
                 155                 160                 165

 Phe Ala Trp Cys Pro Leu Glu Thr Ser Ser Arg Pro Glu Glu Pro
                 170                 175                 180

 Phe Leu Lys Glu Ala Glu Asp Phe Thr Ile Phe Ile Lys Asn His
                 185                 190                 195

 Ile Arg Phe Pro Lys Phe Asn Phe Ser Lys Ser Asn Val Met Asp
                 200                 205                 210

 Val Lys Asp Arg Ser Phe Leu Lys Ser Cys His Phe Gly Pro Lys
                 215                 220                 225

 Asn His Tyr Cys Pro Ile Phe Arg Leu Gly Ser Val Ile Arg Trp
                 230                 235                 240

 Ala Gly Ser Asp Phe Gln Asp Ile Ala Leu Glu Gly Gly Val Ile
                 245                 250                 255

 Gly Ile Asn Ile Glu Trp Asn Cys Asp Leu Asp Lys Ala Ala Ser
                 260                 265                 270

 Glu Cys His Pro His Tyr Ser Phe Ser Arg Leu Asp Asn Lys Leu
                 275                 280                 285

 Ser Lys Ser Val Ser Ser Gly Tyr Asn Phe Arg Phe Ala Arg Tyr
                 290                 295                 300

 Tyr Arg Asp Ala Ala Gly Val Glu Phe Arg Thr Leu Met Lys Ala
                 305                 310                 315

 Tyr Gly Ile Arg Phe Asp Val Met Val Asn Gly Lys Gly Ala Phe
                 320                 325                 330

 Phe Cys Asp Leu Val Leu Ile Tyr Leu Ile Lys Lys Arg Glu Phe
                 335                 340                 345

 Tyr Arg Asp Lys Lys Tyr Glu Glu Val Arg Gly Leu Glu Asp Ser
                 350                 355                 360

 Ser Gln Glu Ala Glu Asp Glu Ala Ser Gly Leu Gly Leu Ser Glu
                 365                 370                 375

 Gln Leu Thr Ser Gly Pro Gly Leu Leu Gly Met Pro Glu Gln Gln
                 380                 385                 390

 Glu Leu Gln Glu Pro Pro Glu Ala Lys Arg Gly Ser Ser Ser Gln
                 395                 400                 405

 Lys Gly Asn Gly Ser Val Cys Pro Gln Leu Leu Glu Pro His Arg
                 410                 415                 420

 Ser Thr


<210> 2230
<211> 698
<212> DNA
<213> Homo sapien

<400> 2230
 gtttgagcag cattgttaga gcctgtggaa aacactttac aactgtgtaa 50

 ctgtcttcat ctttacagag gaatagtcta caaaggaaga cttgtaacct 100

 ggagaagaga cctgtcattt actccatcct ttatagtgat gctacaggac 150

 gaagaggaat ggataaaaac attggcgagc aactcaataa agcgtatgaa 200

 gccttccggc aggcatgcat ggatagagat tctgcagtaa aagaattaca 250

 gcaaaagact gagaactatg agcagagaat acgtgaacaa caggaacagc 300

 tgtcacttca acagactatt attgacaagc taaaatctca gttacttctt 350

 gtgaattcca ctcaagataa caattatggc tgtgttcctc tgcttgaaga 400

 cagtgaaaca agaaagaata atttgactct tgatcagcca caagataaag 450

 tgatttcagg aatagcaaga gaaaaactac caaaggtaga cattgcttct 500

 gcagaaagca gcatttaaat gctgatgcgt gacatagctt cctcatttta 550

 tttttctgaa gtgatctgct ggaattccaa acagaagttc catatataca 600

 aatatgtggc ttaaatattt ctaaatagaa gaactatttt caagtaaaat 650

 aaaggctgag gttttgtatt taaaaaaaaa aaaaaaaaaa aaaaaaaa 698

<210> 2231
<211> 119
<212> PRT
<213> Homo sapien

<400> 2231
 Met Asp Lys Asn Ile Gly Glu Gln Leu Asn Lys Ala Tyr Glu Ala
   1               5                  10                  15

 Phe Arg Gln Ala Cys Met Asp Arg Asp Ser Ala Val Lys Glu Leu
                  20                  25                  30

 Gln Gln Lys Thr Glu Asn Tyr Glu Gln Arg Ile Arg Glu Gln Gln
                  35                  40                  45

 Glu Gln Leu Ser Leu Gln Gln Thr Ile Ile Asp Lys Leu Lys Ser
                  50                  55                  60

 Gln Leu Leu Leu Val Asn Ser Thr Gln Asp Asn Asn Tyr Gly Cys
                  65                  70                  75

 Val Pro Leu Leu Glu Asp Ser Glu Thr Arg Lys Asn Asn Leu Thr
                  80                  85                  90

 Leu Asp Gln Pro Gln Asp Lys Val Ile Ser Gly Ile Ala Arg Glu
                  95                 100                 105

 Lys Leu Pro Lys Val Asp Ile Ala Ser Ala Glu Ser Ser Ile
                 110                 115

<210> 2232
<211> 2137
<212> DNA
<213> Homo sapien

<400> 2232
 ctaattcggg aaacgtgcac cttgactaat tcggttttct gtggctacga 50

 gagcaggctt ggcgggcgga ggcgccagcg gatgtctcat gcaaggatcg 100

 tctctgtggc taagcctcac tttccgctcc gcccgggtgc tctctagagc 150

 ccggtttttc gagtggcagt ctccagggct gccgaataca gcagcgatgg 200

 agaacggcac cgggccctac ggagaagaac gtccacgtga agtccaggag 250

 acgacagtca ccgagggggc tgccaaaatc gcctttccca gtgccaacga 300

 ggtcttttat aacccggtgc aggaattcaa tcgggacctg acatgtgctg 350

 tgatcaccga gtttgctcgc attcagcttg gggccaaagg aatccagatc 400

 aaggttccag gagagaagga cacgcaaaaa gtggtcgtgg acttgtcaga 450

 gcaagaggag gaaaaggttg aactgaaaga gagtgaaaac ctggcctcag 500

 gagaccaacc tcgcacagcg gccgtggggg agatctgtga ggaaggcctg 550

 catgtgctgg aaggcctggc agcttcaggc ctacgttcca ttcgatttgc 600

 cctagaggtg cctgggctca gatctgtggt tgcaaacgat gcctccaccc 650

 gggctgtgga tctcatacgc cggaatgtcc agctcaatga cgtggcccac 700

 ctggtacagc cgagccaagc agatgcccgg atgctgatgt accagcacca 750

 gagggtgtcg gagaggtttg acgtcatcga tctggacccc tatggcagcc 800

 cagccacctt cctggatgca gctgtgcagg ctgtgagtga aggagggttg 850

 ctgtgtgtga cctgcacaga catggcggtg ttggcgggga acagcgggga 900

 gacgtgctac agcaagtacg gggccatggc cctcaagagc cgggcctgcc 950

 acgagatggc cctgagaatc gtcctgcaca gcctggacct ccgcgccaac 1000

 tgctaccagc gcttcgtggt gccgctgctc agcatcagcg ctgacttcta 1050

 cgtgcgtgtt tttgtccgtg tcttcaccgg ccaggccaag gtcaaggcct 1100

 cagccagcaa gcaggcgctg gtgttccagt gtgtgggctg cggggccttc 1150

 caccttcagc gtctcggcaa agcgtcagga gtccccagcg gccgggccaa 1200

 gttctctgca gcctgtggtc cccctgtgac ccccgagtgt gaacactgtg 1250

 ggcaacgaca ccagcttggt ggccccatgt gggcagagcc catccatgac 1300

 ctggattttg tgggccgtgt cctggaggct gtgagcgcta accccggccg 1350

 cttccacacc tcggagcgga tccgaggggt cctgagcgtc atcactgagg 1400

 agctcccgga cgtgcctctg tactacaccc tggaccagct gagcagcacc 1450

 atccactgca acacaccaag cctcctgcag ttgcggtcgg ccctcctcca 1500

 cgctgacttc cgggtctcac tctcccacgc ctgtaagaac gctgtgaaga 1550

 cggatgcccc tgcctctgcc ctctgggaca tcatgcgttg ctgggagaag 1600

 gaatgtccgg tgaaacggga gcgactatca gagactagcc cagcgttccg 1650

 cattctcagt gtggagccca ggctgcaggc caacttcacc atccgggaag 1700

 atgccaaccc cagctcccga cagcgaggac tcaagcgctt ccaggctaac 1750

 ccggaggcca actggggtcc ccggcctcgt gcccggccag ggggcaaggc 1800

 ggccgacgaa gctatggagg agagacgcag gctgcttcag aacaagcgga 1850

 aggagccgcc ggaagatgtg gcccagcggg ctgcccggct caagacattt 1900

 ccttgcaaga ggtttaagga gggcacctgt caacgcgggg accagtgctg 1950

 ctactcccac agccccccga cacccagggt ttctgctgat gctgcccctg 2000

 actgtccaga gacctccaac cagacccccc ctggacctgg ggctgccgct 2050

 gggccaggca tagactgaac caataaagag atgtcacgtc accttcaaaa 2100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 2137

<210> 2233
<211> 659
<212> PRT
<213> Homo sapien

<400> 2233
 Met Gln Gly Ser Ser Leu Trp Leu Ser Leu Thr Phe Arg Ser Ala
   1               5                  10                  15

 Arg Val Leu Ser Arg Ala Arg Phe Phe Glu Trp Gln Ser Pro Gly
                  20                  25                  30

 Leu Pro Asn Thr Ala Ala Met Glu Asn Gly Thr Gly Pro Tyr Gly
                  35                  40                  45

 Glu Glu Arg Pro Arg Glu Val Gln Glu Thr Thr Val Thr Glu Gly
                  50                  55                  60

 Ala Ala Lys Ile Ala Phe Pro Ser Ala Asn Glu Val Phe Tyr Asn
                  65                  70                  75

 Pro Val Gln Glu Phe Asn Arg Asp Leu Thr Cys Ala Val Ile Thr
                  80                  85                  90

 Glu Phe Ala Arg Ile Gln Leu Gly Ala Lys Gly Ile Gln Ile Lys
                  95                 100                 105

 Val Pro Gly Glu Lys Asp Thr Gln Lys Val Val Val Asp Leu Ser
                 110                 115                 120

 Glu Gln Glu Glu Glu Lys Val Glu Leu Lys Glu Ser Glu Asn Leu
                 125                 130                 135

 Ala Ser Gly Asp Gln Pro Arg Thr Ala Ala Val Gly Glu Ile Cys
                 140                 145                 150

 Glu Glu Gly Leu His Val Leu Glu Gly Leu Ala Ala Ser Gly Leu
                 155                 160                 165

 Arg Ser Ile Arg Phe Ala Leu Glu Val Pro Gly Leu Arg Ser Val
                 170                 175                 180

 Val Ala Asn Asp Ala Ser Thr Arg Ala Val Asp Leu Ile Arg Arg
                 185                 190                 195

 Asn Val Gln Leu Asn Asp Val Ala His Leu Val Gln Pro Ser Gln
                 200                 205                 210

 Ala Asp Ala Arg Met Leu Met Tyr Gln His Gln Arg Val Ser Glu
                 215                 220                 225

 Arg Phe Asp Val Ile Asp Leu Asp Pro Tyr Gly Ser Pro Ala Thr
                 230                 235                 240

 Phe Leu Asp Ala Ala Val Gln Ala Val Ser Glu Gly Gly Leu Leu
                 245                 250                 255

 Cys Val Thr Cys Thr Asp Met Ala Val Leu Ala Gly Asn Ser Gly
                 260                 265                 270

 Glu Thr Cys Tyr Ser Lys Tyr Gly Ala Met Ala Leu Lys Ser Arg
                 275                 280                 285

 Ala Cys His Glu Met Ala Leu Arg Ile Val Leu His Ser Leu Asp
                 290                 295                 300

 Leu Arg Ala Asn Cys Tyr Gln Arg Phe Val Val Pro Leu Leu Ser
                 305                 310                 315

 Ile Ser Ala Asp Phe Tyr Val Arg Val Phe Val Arg Val Phe Thr
                 320                 325                 330

 Gly Gln Ala Lys Val Lys Ala Ser Ala Ser Lys Gln Ala Leu Val
                 335                 340                 345

 Phe Gln Cys Val Gly Cys Gly Ala Phe His Leu Gln Arg Leu Gly
                 350                 355                 360

 Lys Ala Ser Gly Val Pro Ser Gly Arg Ala Lys Phe Ser Ala Ala
                 365                 370                 375

 Cys Gly Pro Pro Val Thr Pro Glu Cys Glu His Cys Gly Gln Arg
                 380                 385                 390

 His Gln Leu Gly Gly Pro Met Trp Ala Glu Pro Ile His Asp Leu
                 395                 400                 405

 Asp Phe Val Gly Arg Val Leu Glu Ala Val Ser Ala Asn Pro Gly
                 410                 415                 420

 Arg Phe His Thr Ser Glu Arg Ile Arg Gly Val Leu Ser Val Ile
                 425                 430                 435

 Thr Glu Glu Leu Pro Asp Val Pro Leu Tyr Tyr Thr Leu Asp Gln
                 440                 445                 450

 Leu Ser Ser Thr Ile His Cys Asn Thr Pro Ser Leu Leu Gln Leu
                 455                 460                 465

 Arg Ser Ala Leu Leu His Ala Asp Phe Arg Val Ser Leu Ser His
                 470                 475                 480

 Ala Cys Lys Asn Ala Val Lys Thr Asp Ala Pro Ala Ser Ala Leu
                 485                 490                 495

 Trp Asp Ile Met Arg Cys Trp Glu Lys Glu Cys Pro Val Lys Arg
                 500                 505                 510

 Glu Arg Leu Ser Glu Thr Ser Pro Ala Phe Arg Ile Leu Ser Val
                 515                 520                 525

 Glu Pro Arg Leu Gln Ala Asn Phe Thr Ile Arg Glu Asp Ala Asn
                 530                 535                 540

 Pro Ser Ser Arg Gln Arg Gly Leu Lys Arg Phe Gln Ala Asn Pro
                 545                 550                 555

 Glu Ala Asn Trp Gly Pro Arg Pro Arg Ala Arg Pro Gly Gly Lys
                 560                 565                 570

 Ala Ala Asp Glu Ala Met Glu Glu Arg Arg Arg Leu Leu Gln Asn
                 575                 580                 585

 Lys Arg Lys Glu Pro Pro Glu Asp Val Ala Gln Arg Ala Ala Arg
                 590                 595                 600

 Leu Lys Thr Phe Pro Cys Lys Arg Phe Lys Glu Gly Thr Cys Gln
                 605                 610                 615

 Arg Gly Asp Gln Cys Cys Tyr Ser His Ser Pro Pro Thr Pro Arg
                 620                 625                 630

 Val Ser Ala Asp Ala Ala Pro Asp Cys Pro Glu Thr Ser Asn Gln
                 635                 640                 645

 Thr Pro Pro Gly Pro Gly Ala Ala Ala Gly Pro Gly Ile Asp
                 650                 655

<210> 2234
<211> 2201
<212> DNA
<213> Homo sapien

<400> 2234
 gggggtggga agagctgaag caggcgctct tggctcggcg cggcccgctg 50

 caatccgtgg aggaacgcgc cgccgagcca ccatcatgcc tgggcactta 100

 caggaaggct tcggctgcgt ggtcaccaac cgattcgacc agttatttga 150

 cgacgaatcg gaccccttcg aggtgctgaa ggcagcagag aacaagaaaa 200

 aagaagccgg cgggggcggc gttgggggcc ctggggccaa gagcgcagct 250

 caggccgcgg cccagaccaa ctccaacgcg gcaggcaaac agctgcgcaa 300

 ggagtcccag aaagaccgca agaacccgct gccccccagc gttggcgtgg 350

 ttgacaagaa agaggagacg cagccgcccg tggcgcttaa gaaagaagga 400

 ataagacgag ttggaagaag acctgatcaa caacttcagg gtgaagggaa 450

 aataattgat agaagaccag aaaggcgacc acctcgtgaa cgaagattcg 500

 aaaagccact tgaagaaaag ggtgaaggag gcgaattttc agttgataga 550

 ccgattattg accgacctat tcgaggtcgt ggtggtcttg gaagaggtcg 600

 agggggccgt ggacgtggaa tgggccgagg agatggattt gattctcgtg 650

 gcaaacgtga atttgatagg catagtggaa gtgatagatc tggcctgaag 700

 cacgaggaca aacgtggagg tagcggatct cacaactggg gaactgtcaa 750

 agacgaatta actgacttgg atcaatcaaa tgtgactgag gaaacacctg 800

 aaggtgaaga acatcatcca gtggcagaca ctgaaaataa ggagaatgaa 850

 gttgaagagg taaaagagga gggtccaaaa gagatgactt tggatgagtg 900

 gaaggctatt caaaataagg accgggcaaa agtagaattt aatatccgaa 950

 aaccaaatga aggtgctgat gggcagtgga agaagggatt tgttcttcat 1000

 aaatcaaaga gtgaagaggc tcatgctgaa gattcggtta tggaccatca 1050

 tttccggaag ccagcaaatg atataacgtc tcagctggag atcaattttg 1100

 gagaccttgg ccgcccagga cgtggcggca ggggaggacg aggtggacgt 1150

 gggcgtggtg ggcgcccaaa ccgtggcagc aggaccgaca agtcaagtgc 1200

 ttctgctcct gatgtggatg acccagaggc attcccagct ctggcttaac 1250

 tggatgccat aagacaaccc tggttccttt gtgaaccctt ctgttcaaag 1300

 cttttgcatg cttaaggatt ccaaacgact aagaaattaa aaaaaaaaag 1350

 actgtcattc ataccattca cacctaaaga ctgaatttta tctgttttaa 1400

 aaatgaactt ctcccgctac acagaagtaa caaatatggt agtcagtttt 1450

 gtatttagaa atgtattggt agcagggatg ttttcataat tttcagagat 1500

 tatgcattct tcatgaatac ttttgtattg ctgcttgcaa atatgcattt 1550

 ccaaacttga aatataggtg tgaacagtgt gtaccagttt aaagctttca 1600

 cttcatttgt gttttttaat taaggactta gaagttcccc caattacaaa 1650

 ctggttttaa atattggaca tactggtttt aatacctgct ttgcatattc 1700

 acacatggtc aactgggaca tgttaaactt tgatttgtca aattttatgc 1750

 tgtgtggaat actaactata tgtattttaa cttagtttta atattttcat 1800

 tttgggggaa aaatcttttt tcacttctca tgatagctgt tatatatata 1850

 tgctaaatct ttatatacag aaatatcagt acttgaacaa attcaaagca 1900

 catttggttt attaaccctt gctccttgca tggctcatta ggttcaaatt 1950

 ataactaatt tacattttca gctatattta ctttttaaat gcttgagttt 2000

 cccattttaa aatctaaact agacatctta attggtgaaa gttgtttaaa 2050

 ctacttattg ttggtaggca catcgtgtca agtgaagtag ttttataggt 2100

 atgggttttt tctccccctt caccagggtg ggtggaataa gttgatttgg 2150

 ccaatgtgta atatttaaac tgttctgtaa aataaaaaaa aaaaaaaaaa 2200

 a 2201

<210> 2235
<211> 387
<212> PRT
<213> Homo sapien

<400> 2235
 Met Pro Gly His Leu Gln Glu Gly Phe Gly Cys Val Val Thr Asn
   1               5                  10                  15

 Arg Phe Asp Gln Leu Phe Asp Asp Glu Ser Asp Pro Phe Glu Val
                  20                  25                  30

 Leu Lys Ala Ala Glu Asn Lys Lys Lys Glu Ala Gly Gly Gly Gly
                  35                  40                  45

 Val Gly Gly Pro Gly Ala Lys Ser Ala Ala Gln Ala Ala Ala Gln
                  50                  55                  60

 Thr Asn Ser Asn Ala Ala Gly Lys Gln Leu Arg Lys Glu Ser Gln
                  65                  70                  75

 Lys Asp Arg Lys Asn Pro Leu Pro Pro Ser Val Gly Val Val Asp
                  80                  85                  90

 Lys Lys Glu Glu Thr Gln Pro Pro Val Ala Leu Lys Lys Glu Gly
                  95                 100                 105

 Ile Arg Arg Val Gly Arg Arg Pro Asp Gln Gln Leu Gln Gly Glu
                 110                 115                 120

 Gly Lys Ile Ile Asp Arg Arg Pro Glu Arg Arg Pro Pro Arg Glu
                 125                 130                 135

 Arg Arg Phe Glu Lys Pro Leu Glu Glu Lys Gly Glu Gly Gly Glu
                 140                 145                 150

 Phe Ser Val Asp Arg Pro Ile Ile Asp Arg Pro Ile Arg Gly Arg
                 155                 160                 165

 Gly Gly Leu Gly Arg Gly Arg Gly Gly Arg Gly Arg Gly Met Gly
                 170                 175                 180

 Arg Gly Asp Gly Phe Asp Ser Arg Gly Lys Arg Glu Phe Asp Arg
                 185                 190                 195

 His Ser Gly Ser Asp Arg Ser Gly Leu Lys His Glu Asp Lys Arg
                 200                 205                 210

 Gly Gly Ser Gly Ser His Asn Trp Gly Thr Val Lys Asp Glu Leu
                 215                 220                 225

 Thr Asp Leu Asp Gln Ser Asn Val Thr Glu Glu Thr Pro Glu Gly
                 230                 235                 240

 Glu Glu His His Pro Val Ala Asp Thr Glu Asn Lys Glu Asn Glu
                 245                 250                 255

 Val Glu Glu Val Lys Glu Glu Gly Pro Lys Glu Met Thr Leu Asp
                 260                 265                 270

 Glu Trp Lys Ala Ile Gln Asn Lys Asp Arg Ala Lys Val Glu Phe
                 275                 280                 285

 Asn Ile Arg Lys Pro Asn Glu Gly Ala Asp Gly Gln Trp Lys Lys
                 290                 295                 300

 Gly Phe Val Leu His Lys Ser Lys Ser Glu Glu Ala His Ala Glu
                 305                 310                 315

 Asp Ser Val Met Asp His His Phe Arg Lys Pro Ala Asn Asp Ile
                 320                 325                 330

 Thr Ser Gln Leu Glu Ile Asn Phe Gly Asp Leu Gly Arg Pro Gly
                 335                 340                 345

 Arg Gly Gly Arg Gly Gly Arg Gly Gly Arg Gly Arg Gly Gly Arg
                 350                 355                 360

 Pro Asn Arg Gly Ser Arg Thr Asp Lys Ser Ser Ala Ser Ala Pro
                 365                 370                 375

 Asp Val Asp Asp Pro Glu Ala Phe Pro Ala Leu Ala
                 380                 385

<210> 2236
<211> 3863
<212> DNA
<213> Homo sapien

<400> 2236
 gagatggaga ctcgctctgt cacccaggct ggagtgcaat ggtgagatct 50

 cggctcactg caacctccac ctcctgggtt caggcgattc tcctgcctcc 100

 caatcctagt agctgggagt atcaggtgag tcgcagcccc aacgcacgcc 150

 cggcataatt tttttatttt tagtcgagac gggtttcacc acgttggcca 200

 ggatggtctc gaactcctga cctcaggtga tccacccgcc tcggcctccc 250

 aaagcactgg gattacaggc gtgagccacc gcgcccggcc tccatatcca 300

 ttcttgggaa cacttgttgc ttagctgaac ggagcccgca tcctgctgtg 350

 gcggcactcg ccccggtgct ggtctgagca gacgcctcct ttctcttgca 400

 gaagaagtaa gtgaggaaga aatgagtgaa gatgaagaac gagaaaatga 450

 aaaccacctc ttggttgttc cagagtcacg gttcgaccga gattccgggg 500

 agagtgaaga agcagaggaa gaagtgggtg agggaacgcc gcagagcagc 550

 gccctgacag agggcgacta tgtgcccgac tcccctgccc tgtcgcccat 600

 cgagctcaag caggagctgc ccaagtacct gccggccctg cagggctgcc 650

 ggagcgtcga ggagttccag tgcctgaaca ggatcgagga gggcacctat 700

 ggagtggtct acagagcaaa agacaagaaa acagatgaaa ttgtggctct 750

 aaagcggctg aagatggaga aggagaagga gggcttcccg atcacgtcgc 800

 tgagggagat caacaccatc ctcaaggccc agcatcccaa catcgtcacc 850

 gttagagaga ttgtggtggg cagcaacatg gacaagatct acatcgtgat 900

 gaactatgtg gagcacgacc tcaagagcct gatggagacc atgaaacagc 950

 ccttcctgcc aggggaggtg aagaccctga tgatccagct gctgcgtggg 1000

 gtgaaacacc tgcacgacaa ctggatcctg caccgtgacc tcaagacgtc 1050

 caacctgctg ctgagccacg ccggcatcct caaggtgggt gacttcgggc 1100

 tggcgcggga gtacggatcc cctctgaagg cctacacccc ggtcgtggtg 1150

 accctgtggt accgcgcccc agagctgctg cttggtgcca aggaatactc 1200

 cacggccgtg gacatgtggt cagtgggttg catcttcggg gagctgctga 1250

 ctcagaagcc tctgttcccc gggaagtcag aaatcgatca gatcaacaag 1300

 gtgttcaagg atctggggac ccctagtgag aaaatctggc ccggctacag 1350

 cgagctccca gcagtcaaga agatgacctt cagcgagcac ccctacaaca 1400

 acctccgcaa gcgcttcggg gctctgctct cagaccaggg cttcgacctc 1450

 atgaacaagt tcctgaccta cttccccggg aggaggatca gcgctgagga 1500

 cggcctcaag catgagtatt tccgcgagac ccccctcccc atcgacccct 1550

 ccatgttccc cacgtggccc gccaagagcg agcagcagcg tgtgaagcgg 1600

 ggcaccagcc cgaggccccc tgagggaggc ctgggctaca gccagctggg 1650

 tgacgacgac ctgaaggaga cgggcttcca ccttaccacc acgaaccagg 1700

 gggcctctgc cgcgggcccc ggcttcagcc tcaagttctg aaggtcagag 1750

 tggaccccgt catggggaga actcagccgg gaccacaggc gtggctactg 1800

 cggctggagc tgcgatgaga ctcggaactc ctcgtcttac tttgtgctcc 1850

 atgttttgtt tttgtatttt ggtttgtaaa tttgtagaat taaatcattt 1900

 tccttgtaaa cccgaattcg ggaccatcac agtttgatta gcctcagcct 1950

 caagagctgg cacatgcttg tgaacttgtg ctttcatatt ttcctaacct 2000

 gtgtgctctt tgtgggagga ataacccaga ctaggaatgc cagcatctgc 2050

 caagcagttg ggataattct tcactattcc acccttgcca cagtactatg 2100

 ggtaggagtg acagctcgaa atatctacaa acaagtcact aaaaaagcta 2150

 aaagatgcca ggatcctgat gaaccaccac ctccaccaag accaatgctc 2200

 agattttacc tgattggtgg tggtatcccc atcattgttt gcggcataac 2250

 tgcaggcagc gaacattaag aattacggca gtcggccaaa cgcaccctat 2300

 tgctggatgg catgggaacc ctccttggga gccttctatg ggccagccag 2350

 cttcagcact tttgtaaact gcatgtactt tctgagcata tttattcagt 2400

 tgaaaagaca ccctgagcgc aaatatgagc ttaaggagcc cactggccag 2450

 caacagagat tggcatgcca atgaaaatgg cgaaataaat catcaggaaa 2500

 tcatttcttt gtctctgatt tctacatcag ccttggaaaa tgagcacact 2550

 tttcattctc agctcttggg gccagcctta ctttgctctt atatgttgca 2600

 ctgtggatgt ttggggcttt ggctgtttct ttgtattacc ctttggactt 2650

 ggtttttagc ttcgtttttg gagccacaag tttaagcttc agtgcattct 2700

 tcatggtcca ccattgtgtt aatagggagg atcttagact tgcgtggatc 2750

 atgacttgct gcccaggacg gagctcgtat tcagtgcaag tcaacgtcca 2800

 gccccccaac tctaatggga cgaatggaga ggcacccaaa tgccccaata 2850

 gcagtgcgga gtcttcatgc acaaacaaaa gtgattcaag cttcaaaatt 2900

 cctcccaggg ctgcaaatta acaaacttgc aggcggctgc agctcagtgc 2950

 catgccaatt ctttaccttt gaactccacc cctcagcttg ataatagtct 3000

 gacagaacat tcaatggaca atgatattaa aatgcacgct ggcgccttta 3050

 gaagttcagt ttcgaacaaa tgtgcactca agccgccacc ataaaaacag 3100

 aagtaaagga caccgggcaa gccgactcac agtcctgaga gaatatgcct 3150

 acgatgtccc aacgagcgtg gaaggaagcg tgcagaacgg cttacctaaa 3200

 agccggctgg gcaataacga aggacactcg aggagccgaa gagcttattt 3250

 agcctacaga gagagacagt acaacccacc ccagcaagac agcagcgatg 3300

 cttgtagcac acttcccaaa agtagcagaa attttgaaaa gccagtttca 3350

 accactagta aaaagatgcg ttaagggaag ccagctgtgg ttgaacttca 3400

 aaatcagcaa aaatcttatg gcctcaactt ggccattcag aatggaccaa 3450

 ttaaaagcaa tgggcaggag ggacccttgc tcggtaccga tagcactggc 3500

 aatgttacca ctggattatg gaaacacgaa actactgtgt aacattgctg 3550

 ggcttcctag gcagaaattc atataaactg tgatactcac attccttgaa 3600

 gctatgagca tttaaaaact gtttacagcc accataggga ttcaaaagaa 3650

 tttggaataa actttgaagt tttggatttt acttattttt atccccaaat 3700

 tgttgctatt ttttaggatc tgaaacaaaa tctttctaaa acattgtttt 3750

 agttgtcaaa gcaccaacag gacattttgg gatgtgaaat gtaatttctt 3800

 ggaatctgta atttgtactt aatatttcag gcttgtattt aatataataa 3850

 ataggtgttt gtt 3863

<210> 2237
<211> 439
<212> PRT
<213> Homo sapien

<400> 2237
 Met Ser Glu Asp Glu Glu Arg Glu Asn Glu Asn His Leu Leu Val
   1               5                  10                  15

 Val Pro Glu Ser Arg Phe Asp Arg Asp Ser Gly Glu Ser Glu Glu
                  20                  25                  30

 Ala Glu Glu Glu Val Gly Glu Gly Thr Pro Gln Ser Ser Ala Leu
                  35                  40                  45

 Thr Glu Gly Asp Tyr Val Pro Asp Ser Pro Ala Leu Ser Pro Ile
                  50                  55                  60

 Glu Leu Lys Gln Glu Leu Pro Lys Tyr Leu Pro Ala Leu Gln Gly
                  65                  70                  75

 Cys Arg Ser Val Glu Glu Phe Gln Cys Leu Asn Arg Ile Glu Glu
                  80                  85                  90

 Gly Thr Tyr Gly Val Val Tyr Arg Ala Lys Asp Lys Lys Thr Asp
                  95                 100                 105

 Glu Ile Val Ala Leu Lys Arg Leu Lys Met Glu Lys Glu Lys Glu
                 110                 115                 120

 Gly Phe Pro Ile Thr Ser Leu Arg Glu Ile Asn Thr Ile Leu Lys
                 125                 130                 135

 Ala Gln His Pro Asn Ile Val Thr Val Arg Glu Ile Val Val Gly
                 140                 145                 150

 Ser Asn Met Asp Lys Ile Tyr Ile Val Met Asn Tyr Val Glu His
                 155                 160                 165

 Asp Leu Lys Ser Leu Met Glu Thr Met Lys Gln Pro Phe Leu Pro
                 170                 175                 180

 Gly Glu Val Lys Thr Leu Met Ile Gln Leu Leu Arg Gly Val Lys
                 185                 190                 195

 His Leu His Asp Asn Trp Ile Leu His Arg Asp Leu Lys Thr Ser
                 200                 205                 210

 Asn Leu Leu Leu Ser His Ala Gly Ile Leu Lys Val Gly Asp Phe
                 215                 220                 225

 Gly Leu Ala Arg Glu Tyr Gly Ser Pro Leu Lys Ala Tyr Thr Pro
                 230                 235                 240

 Val Val Val Thr Leu Trp Tyr Arg Ala Pro Glu Leu Leu Leu Gly
                 245                 250                 255

 Ala Lys Glu Tyr Ser Thr Ala Val Asp Met Trp Ser Val Gly Cys
                 260                 265                 270

 Ile Phe Gly Glu Leu Leu Thr Gln Lys Pro Leu Phe Pro Gly Lys
                 275                 280                 285

 Ser Glu Ile Asp Gln Ile Asn Lys Val Phe Lys Asp Leu Gly Thr
                 290                 295                 300

 Pro Ser Glu Lys Ile Trp Pro Gly Tyr Ser Glu Leu Pro Ala Val
                 305                 310                 315

 Lys Lys Met Thr Phe Ser Glu His Pro Tyr Asn Asn Leu Arg Lys
                 320                 325                 330

 Arg Phe Gly Ala Leu Leu Ser Asp Gln Gly Phe Asp Leu Met Asn
                 335                 340                 345

 Lys Phe Leu Thr Tyr Phe Pro Gly Arg Arg Ile Ser Ala Glu Asp
                 350                 355                 360

 Gly Leu Lys His Glu Tyr Phe Arg Glu Thr Pro Leu Pro Ile Asp
                 365                 370                 375

 Pro Ser Met Phe Pro Thr Trp Pro Ala Lys Ser Glu Gln Gln Arg
                 380                 385                 390

 Val Lys Arg Gly Thr Ser Pro Arg Pro Pro Glu Gly Gly Leu Gly
                 395                 400                 405

 Tyr Ser Gln Leu Gly Asp Asp Asp Leu Lys Glu Thr Gly Phe His
                 410                 415                 420

 Leu Thr Thr Thr Asn Gln Gly Ala Ser Ala Ala Gly Pro Gly Phe
                 425                 430                 435

 Ser Leu Lys Phe


<210> 2238
<211> 1687
<212> DNA
<213> Homo sapien

<400> 2238
 tgtggctcgg gcggcggcgg cgcggcggcg gcagaggggg ctccggggtc 50

 ggaccatccg ctctccctgc gctctccgca ccgcgcttaa atgatgtatt 100

 ttgtgatcgc agcgatgaaa gctcaaattg aaattattcc atgcaagatc 150

 tgtggagaca aatcatcagg aatccattat ggtgtcatta catgtgaagg 200

 ctgcaagggc tttttcagga gaagtcagca aagcaatgcc acctactcct 250

 gtcctcgtca gaagaactgt ttgattgatc gaaccagtag aaaccgctgc 300

 caacactgtc gattacagaa atgccttgcc gtagggatgt ctcgagatgc 350

 tgtaaaattt ggccgaatgt caaaaaagca gagagacagc ttgtatgcag 400

 aagtacagaa acaccggatg cagcagcagc agcgcgacca ccagcagcag 450

 cctggagagg ctgagccgct gacgcccacc tacaacatct cggccaacgg 500

 gctgacggaa cttcacgacg acctcagtaa ctacattgac gggcacaccc 550

 ctgaggggag taaggcagac tccgccgtca gcagcttcta cctggacata 600

 cagccttccc cagaccagtc aggtcttgat atcaatggaa tcaaaccaga 650

 accaatatgt gactacacac cagcatcagg cttctttccc tactgttcgt 700

 tcaccaacgg cgagacttcc ccaactgtgt ccatggcaga attagaacac 750

 cttgcacaga atatatctaa atcgcatctg gaaacctgcc aatacttgag 800

 agaagagctc cagcagataa cgtggcagac ctttttacag gaagaaattg 850

 agaactatca aaacaagcag cgggaggtga tgtggcaatt gtgtgccatc 900

 aaaattacag aagctataca gtatgtggtg gagtttgcca aacgcattga 950

 tggatttatg gaactgtgtc aaaatgatca aattgtgctt ctaaaagcag 1000

 gttctctaga ggtggtgttt atcagaatgt gccgtgcctt tgactctcag 1050

 aacaacaccg tgtactttga tgggaagtat gccagccccg acgtcttcaa 1100

 atccttaggt tgtgaagact ttattagctt tgtgtttgaa tttggaaaga 1150

 gtttatgttc tatgcacctg actgaagatg aaattgcatt attttctgca 1200

 tttgtactga tgtcagcaga tcgctcatgg ctgcaagaaa aggtaaaaat 1250

 tgaaaaactg caacagaaaa ttcagctagc tcttcaacac gtcctacaga 1300

 agaatcaccg agaagatgga atactaacaa agttaatatg caaggtgtct 1350

 acattaagag ccttatgtgg acgacataca gaaaagctaa tggcatttaa 1400

 agcaatatac ccagacattg tgcgacttca ttttcctcca ttatacaagg 1450

 agttgttcac ttcagaattt gagccagcaa tgcaaattga tgggtaaatg 1500

 ttatcaccta agcacttcta gaatgtctga agtacaaaca tgaaaaacaa 1550

 acaaaaaaat taaccgagac actttatatg gccctgcaca gacctggagc 1600

 gccacacact gcacatcttt tggtgatcgg ggtcaggcaa aggaggggaa 1650

 acaatgaaaa caaataaagt tgaacttgtt tttctca 1687

<210> 2239
<211> 468
<212> PRT
<213> Homo sapien

<400> 2239
 Met Met Tyr Phe Val Ile Ala Ala Met Lys Ala Gln Ile Glu Ile
   1               5                  10                  15

 Ile Pro Cys Lys Ile Cys Gly Asp Lys Ser Ser Gly Ile His Tyr
                  20                  25                  30

 Gly Val Ile Thr Cys Glu Gly Cys Lys Gly Phe Phe Arg Arg Ser
                  35                  40                  45

 Gln Gln Ser Asn Ala Thr Tyr Ser Cys Pro Arg Gln Lys Asn Cys
                  50                  55                  60

 Leu Ile Asp Arg Thr Ser Arg Asn Arg Cys Gln His Cys Arg Leu
                  65                  70                  75

 Gln Lys Cys Leu Ala Val Gly Met Ser Arg Asp Ala Val Lys Phe
                  80                  85                  90

 Gly Arg Met Ser Lys Lys Gln Arg Asp Ser Leu Tyr Ala Glu Val
                  95                 100                 105

 Gln Lys His Arg Met Gln Gln Gln Gln Arg Asp His Gln Gln Gln
                 110                 115                 120

 Pro Gly Glu Ala Glu Pro Leu Thr Pro Thr Tyr Asn Ile Ser Ala
                 125                 130                 135

 Asn Gly Leu Thr Glu Leu His Asp Asp Leu Ser Asn Tyr Ile Asp
                 140                 145                 150

 Gly His Thr Pro Glu Gly Ser Lys Ala Asp Ser Ala Val Ser Ser
                 155                 160                 165

 Phe Tyr Leu Asp Ile Gln Pro Ser Pro Asp Gln Ser Gly Leu Asp
                 170                 175                 180

 Ile Asn Gly Ile Lys Pro Glu Pro Ile Cys Asp Tyr Thr Pro Ala
                 185                 190                 195

 Ser Gly Phe Phe Pro Tyr Cys Ser Phe Thr Asn Gly Glu Thr Ser
                 200                 205                 210

 Pro Thr Val Ser Met Ala Glu Leu Glu His Leu Ala Gln Asn Ile
                 215                 220                 225

 Ser Lys Ser His Leu Glu Thr Cys Gln Tyr Leu Arg Glu Glu Leu
                 230                 235                 240

 Gln Gln Ile Thr Trp Gln Thr Phe Leu Gln Glu Glu Ile Glu Asn
                 245                 250                 255

 Tyr Gln Asn Lys Gln Arg Glu Val Met Trp Gln Leu Cys Ala Ile
                 260                 265                 270

 Lys Ile Thr Glu Ala Ile Gln Tyr Val Val Glu Phe Ala Lys Arg
                 275                 280                 285

 Ile Asp Gly Phe Met Glu Leu Cys Gln Asn Asp Gln Ile Val Leu
                 290                 295                 300

 Leu Lys Ala Gly Ser Leu Glu Val Val Phe Ile Arg Met Cys Arg
                 305                 310                 315

 Ala Phe Asp Ser Gln Asn Asn Thr Val Tyr Phe Asp Gly Lys Tyr
                 320                 325                 330

 Ala Ser Pro Asp Val Phe Lys Ser Leu Gly Cys Glu Asp Phe Ile
                 335                 340                 345

 Ser Phe Val Phe Glu Phe Gly Lys Ser Leu Cys Ser Met His Leu
                 350                 355                 360

 Thr Glu Asp Glu Ile Ala Leu Phe Ser Ala Phe Val Leu Met Ser
                 365                 370                 375

 Ala Asp Arg Ser Trp Leu Gln Glu Lys Val Lys Ile Glu Lys Leu
                 380                 385                 390

 Gln Gln Lys Ile Gln Leu Ala Leu Gln His Val Leu Gln Lys Asn
                 395                 400                 405

 His Arg Glu Asp Gly Ile Leu Thr Lys Leu Ile Cys Lys Val Ser
                 410                 415                 420

 Thr Leu Arg Ala Leu Cys Gly Arg His Thr Glu Lys Leu Met Ala
                 425                 430                 435

 Phe Lys Ala Ile Tyr Pro Asp Ile Val Arg Leu His Phe Pro Pro
                 440                 445                 450

 Leu Tyr Lys Glu Leu Phe Thr Ser Glu Phe Glu Pro Ala Met Gln
                 455                 460                 465

 Ile Asp Gly


<210> 2240
<211> 1701
<212> DNA
<213> Homo sapien

<400> 2240
 aaggagcaca gttccaggcg gggctgagct agggcgtagc tgtgatttca 50

 ggggcacctc tggcggctgc cgtgatttga gaatctcggg tctcttggct 100

 gactgatcct gggagactgt ggatgaataa tgctgggcac ggccccaccc 150

 ggaggctgcg aggcttgggg gtcctggccg gggtggctct gctcgctgcc 200

 ctctggctcc tgtggctgct ggggtcagcc cctcggggta ccccggcacc 250

 ccagcccacg atcaccatcc ttgtctggca ctggcccttc actgaccagc 300

 ccccagagct gcccagcgac acctgcaccc gctacggcat cgcccgctgc 350

 cacctgagtg ccaaccgaag cctgctggcc agcgccgacg ccgtggtctt 400

 ccaccaccgc gagctgcaga cccggcggtc ccacctgccc ctggcccagc 450

 ggccgcgagg gcagccctgg gtgtgggcct ccatggagtc tcctagccac 500

 acccacggcc tcagccacct ccgaggcatc ttcaactggg tgctgagcta 550

 ccggcgcgac tcggacatct ttgtgcccta tggccgcctg gagccccact 600

 gggggccctc gccaccgctg ccagccaaga gcagggtggc cgcctgggtg 650

 gtcagcaact tccaggagcg gcagctgcgt gccaggctgt accggcagct 700

 ggcgcctcat ctgcgggtgg atgtctttgg ccgtgccaat ggacggccac 750

 tgtgcgccag ctgcctggtg cccaccgtgg cccagtaccg cttctacctg 800

 tcctttgaga actctcagca ccgcgactac attacggaga aattctggcg 850

 caacgcactg gtggctggca ctgtgccagt ggtgctgggg cccccacggg 900

 ccacctatga ggccttcgtg ccggctgacg ccttcgtgca tgtggatgac 950

 tttggctcag cccgagagct ggcggctttc ctcactggca tgaatgagag 1000

 ccgataccaa cgcttctttg cctggcgtga caggctccgc gtgcgactgt 1050

 tcaccgactg gcgggaacgt ttctgtgcca tctgtgaccg ctacccacac 1100

 ctaccccgca gccaagtcta tgaggacctt gagggttggt ttcaggcctg 1150

 agatccgctg gccgggggag gtgggtgtgg gtggaagggc tgggtgtcga 1200

 aatcaaacca ccaggcatcc ggcccttacc ggcaagcagc gggctaacgg 1250

 gaggctgggc acagaggtca ggaagcaggg gtggggggtg caggtgggca 1300

 ctggagcatg cagaggaggt gagagtggga gggaggtaac gggtgcctgc 1350

 tgcggcagac gggaggggaa aggctgccga ggaccctccc caccctgaac 1400

 aaatcttggg tgggtgaagg cctggctgga agagggtgaa aggcagggcc 1450

 cttggggctg gggggcaccc cagcctgaag tttgtggggg ccaaacctgg 1500

 gaccccgagc ttcctcggta gcagaggccc tgtggtcccc gagacacagg 1550

 cacgggtccc tgccacgtcc atagttctga ggtccctgtg tgtaggctgg 1600

 ggcggggccc aggagaccac ggggagcaaa ccagcttgtt ctgggctcag 1650

 ggagggaggg cggtggacaa taaacgtctg agcagtgaaa aaaaaaaaaa 1700

 a 1701

<210> 2241
<211> 342
<212> PRT
<213> Homo sapien

<400> 2241
 Met Asn Asn Ala Gly His Gly Pro Thr Arg Arg Leu Arg Gly Leu
   1               5                  10                  15

 Gly Val Leu Ala Gly Val Ala Leu Leu Ala Ala Leu Trp Leu Leu
                  20                  25                  30

 Trp Leu Leu Gly Ser Ala Pro Arg Gly Thr Pro Ala Pro Gln Pro
                  35                  40                  45

 Thr Ile Thr Ile Leu Val Trp His Trp Pro Phe Thr Asp Gln Pro
                  50                  55                  60

 Pro Glu Leu Pro Ser Asp Thr Cys Thr Arg Tyr Gly Ile Ala Arg
                  65                  70                  75

 Cys His Leu Ser Ala Asn Arg Ser Leu Leu Ala Ser Ala Asp Ala
                  80                  85                  90

 Val Val Phe His His Arg Glu Leu Gln Thr Arg Arg Ser His Leu
                  95                 100                 105

 Pro Leu Ala Gln Arg Pro Arg Gly Gln Pro Trp Val Trp Ala Ser
                 110                 115                 120

 Met Glu Ser Pro Ser His Thr His Gly Leu Ser His Leu Arg Gly
                 125                 130                 135

 Ile Phe Asn Trp Val Leu Ser Tyr Arg Arg Asp Ser Asp Ile Phe
                 140                 145                 150

 Val Pro Tyr Gly Arg Leu Glu Pro His Trp Gly Pro Ser Pro Pro
                 155                 160                 165

 Leu Pro Ala Lys Ser Arg Val Ala Ala Trp Val Val Ser Asn Phe
                 170                 175                 180

 Gln Glu Arg Gln Leu Arg Ala Arg Leu Tyr Arg Gln Leu Ala Pro
                 185                 190                 195

 His Leu Arg Val Asp Val Phe Gly Arg Ala Asn Gly Arg Pro Leu
                 200                 205                 210

 Cys Ala Ser Cys Leu Val Pro Thr Val Ala Gln Tyr Arg Phe Tyr
                 215                 220                 225

 Leu Ser Phe Glu Asn Ser Gln His Arg Asp Tyr Ile Thr Glu Lys
                 230                 235                 240

 Phe Trp Arg Asn Ala Leu Val Ala Gly Thr Val Pro Val Val Leu
                 245                 250                 255

 Gly Pro Pro Arg Ala Thr Tyr Glu Ala Phe Val Pro Ala Asp Ala
                 260                 265                 270

 Phe Val His Val Asp Asp Phe Gly Ser Ala Arg Glu Leu Ala Ala
                 275                 280                 285

 Phe Leu Thr Gly Met Asn Glu Ser Arg Tyr Gln Arg Phe Phe Ala
                 290                 295                 300

 Trp Arg Asp Arg Leu Arg Val Arg Leu Phe Thr Asp Trp Arg Glu
                 305                 310                 315

 Arg Phe Cys Ala Ile Cys Asp Arg Tyr Pro His Leu Pro Arg Ser
                 320                 325                 330

 Gln Val Tyr Glu Asp Leu Glu Gly Trp Phe Gln Ala
                 335                 340

<210> 2242
<211> 1723
<212> DNA
<213> Homo sapien

<400> 2242
 tcgcggaggc ttggggcagc cgggtagctc ggaggtcgtg gcgctggggg 50

 ctagcaccag cgctctgtcg ggaggcgcag cggttaggtg gaccggtcag 100

 cggactcacc ggccagggcg ctcggtgctg gaatttgata ttcattgatc 150

 cgggttttat ccctcttctt ttttcttaaa catttttttt taaaactgta 200

 ttgtttctcg ttttaattta tttttgcttg ccattcccca cttgaatcgg 250

 gccgacggct tggggagatt gctctacttc cccaaatcac tgtggatttt 300

 ggaaaccagc agaaagagga aagaggtagc aagagctcca gagagaagtc 350

 gaggaagaga gagacggggt cagagagagc gcgcgggcgt gcgagcagcg 400

 aaagcgacag gggcaaagtg agtgacctgc ttttgggggt gaccgccgga 450

 gcgcggcgtg agccctcccc cttgggatcc cgcagctgac cagtcgcgct 500

 gacggacaga cagacagaca ccgcccccag ccccagctac cacctcctcc 550

 ccggccggcg gcggacagtg gacgcggcgg cgagccgcgg gcaggggccg 600

 gagcccgcgc ccggaggcgg ggtggagggg gtcggggctc gcggcgtcgc 650

 actgaaactt ttcgtccaac ttctgggctg ttctcgcttc ggaggagccg 700

 tggtccgcgc gggggaagcc gagccgagcg gagccgcgag aagtgctagc 750

 tcgggccggg aggagccgca gccggaggag ggggaggagg aagaagagaa 800

 ggaagaggag agggggccgc agtggcgact cggcgctcgg aagccgggct 850

 catggacggg tgaggcggcg gtgtgcgcag acagtgctcc agccgcgcgc 900

 gctccccagg ccctggcccg ggcctcgggc cggggaggaa gagtagctcg 950

 ccgaggcgcc gaggagagcg ggccgcccca cagcccgagc cggagaggga 1000

 gcgcgagccg cgccggcccc ggtcgggcct ccgaaaccat gaactttctg 1050

 ctgtcttggg tgcattggag ccttgccttg ctgctctacc tccaccatgc 1100

 caagtggtcc caggctgcac ccatggcaga aggaggaggg cagaatcatc 1150

 acgaagtggt gaagttcatg gatgtctatc agcgcagcta ctgccatcca 1200

 atcgagaccc tggtggacat cttccaggag taccctgatg agatcgagta 1250

 catcttcaag ccatcctgtg tgcccctgat gcgatgcggg ggctgctgca 1300

 atgacgaggg cctggagtgt gtgcccactg aggagtccaa catcaccatg 1350

 cagattatgc ggatcaaacc tcaccaaggc cagcacatag gagagatgag 1400

 cttcctacag cacaacaaat gtgaatgcag accaaagaaa gatagagcaa 1450

 gacaagaaaa aaaatcagtt cgaggaaagg gaaaggggca aaaacgaaag 1500

 cgcaagaaat cccggtataa gtcctggagc gttccctgtg ggccttgctc 1550

 agagcggaga aagcatttgt ttgtacaaga tccgcagacg tgtaaatgtt 1600

 cctgcaaaaa cacagactcg cgttgcaagg cgaggcagct tgagttaaac 1650

 gaacgtactt gcagatgtga caagccgagg cggtgagccg ggcaggagga 1700

 aggagcctcc ctcagggttt cgg 1723

<210> 2243
<211> 191
<212> PRT
<213> Homo sapien

<400> 2243
 Met Asn Phe Leu Leu Ser Trp Val His Trp Ser Leu Ala Leu Leu
   1               5                  10                  15

 Leu Tyr Leu His His Ala Lys Trp Ser Gln Ala Ala Pro Met Ala
                  20                  25                  30

 Glu Gly Gly Gly Gln Asn His His Glu Val Val Lys Phe Met Asp
                  35                  40                  45

 Val Tyr Gln Arg Ser Tyr Cys His Pro Ile Glu Thr Leu Val Asp
                  50                  55                  60

 Ile Phe Gln Glu Tyr Pro Asp Glu Ile Glu Tyr Ile Phe Lys Pro
                  65                  70                  75

 Ser Cys Val Pro Leu Met Arg Cys Gly Gly Cys Ser Asn Asp Glu
                  80                  85                  90

 Gly Leu Glu Cys Val Pro Thr Glu Glu Ser Asn Ile Thr Met Gln
                  95                 100                 105

 Ile Met Arg Ile Lys Pro His Gln Gly Gln His Ile Gly Glu Met
                 110                 115                 120

 Ser Phe Leu Gln His Asn Lys Cys Glu Cys Arg Pro Lys Lys Asp
                 125                 130                 135

 Arg Ala Arg Gln Glu Asn Pro Cys Gly Pro Cys Ser Glu Arg Arg
                 140                 145                 150

 Lys His Leu Phe Val Gln Asp Pro Gln Thr Cys Lys Cys Ser Cys
                 155                 160                 165

 Lys Asn Thr His Ser Arg Cys Lys Ala Arg Gln Leu Glu Leu Asn
                 170                 175                 180

 Glu Arg Thr Cys Arg Cys Asp Lys Pro Arg Arg
                 185                 190

<210> 2244
<211> 1840
<212> DNA
<213> Homo sapien

<400> 2244
 cccattaggt gacaggtttt tagagaagcc aatcacgtcg ccgcggtcct 50

 ggttctaaag tcctcgctca cccacccgga ctcattctcc ccagacgcca 100

 aggatggtgg tcatggcgcc ccgaaccctc ttcctgctgc tctcgggggc 150

 cctgaccctg accgagacct gggcgggctc ccactccatg aggtatttca 200

 gcgccgccgt gtcccggccc ggccgcgggg agccccgctt catcgccatg 250

 ggctacgtgg acgacacgca gttcgtgcgg ttcgacagcg actcggcgtg 300

 tccgaggatg gagccgcggg cgccgtgggt ggagcaggag gggccggagt 350

 attgggaaga ggagacacgg aacaccaagg cccacgcaca gactgacaga 400

 atgaacctgc agaccctgcg cggctactac aaccagagcg aggccagttc 450

 tcacaccctc cagtggatga ttggctgcga cctggggtcc gacggacgcc 500

 tcctccgcgg gtatgaacag tatgcctacg atggcaagga ttacctcgcc 550

 ctgaacgagg acctgcgctc ctggaccgca gcggacactg cggctcagat 600

 ctccaagcgc aagtgtgagg cggccaatgt ggctgaacaa aggagagcct 650

 acctggaggg cacgtgcgtg gagtggctcc acagatacct ggagaacggg 700

 aaggagatgc tgcagcgcgc ggaccccccc aagacacacg tgacccacca 750

 ccctgtcttt gactatgagg ccaccctgag gtgctgggcc ctgggcttct 800

 accctgcgga gatcatactg acctggcagc gggatgggga ggaccagacc 850

 caggacgtgg agctcgtgga gaccaggcct gcaggggatg gaaccttcca 900

 gaagtgggca gctgtggtgg tgccttctgg agaggagcag agatacacgt 950

 gccatgtgca gcatgagggg ctgccggagc ccctcatgct gagatggaag 1000

 cagtcttccc tgcccaccat ccccatcatg ggtatcgttg ctggcctggt 1050

 tgtccttgca gctgtagtca ctggagctgc ggtcgctgct gtgctgtgga 1100

 gaaagaagag ctcagattga aaaggaggga gctactctca ggctgcaagt 1150

 aagtatgaag gaggctgatc cctgagatcc ttgggatctt gtgtttggga 1200

 gccatggggg agctcaccca ccccacaatt cctcctctgg ccacatctcc 1250

 tgtggtctct gaccaggtgc tgtttttgtt ctactctagg cagtgacagt 1300

 gcccagggct ctaatgtgtc tctcacggct tgtaaatgtg acaccccggg 1350

 gggcctgatg tgtgtgggtt gttgagggga acaggggaca tagctgtgct 1400

 atgaggtttc tttgacttca atgtattgag catgtgatgg gctgtttaaa 1450

 gtgtcacccc tcactgtgac tgatatgaat ttgttcatga atatttttct 1500

 gtagtgtgaa acagctgccc tgtgtgggac tgagtggcaa gtccctttgt 1550

 gacttcaaga accctgactt ctctttgtgc agagaccagc ccacccctgt 1600

 gcccaccatg accctcttcc tcatgctgaa ctgcattcct tccccaatca 1650

 cctttcctgt tccagaaaag gggctgggat gtctccgtct ctgtctcaaa 1700

 tttgtggtcc actgagctat aacttacttc tgtattaaaa ttagaatctg 1750

 agtataaatt tactttttca aattatttcc aagagagatt gatgggttaa 1800

 ttaaaggaga agattcctga aatttgagag acaaaataaa 1840

<210> 2245
<211> 338
<212> PRT
<213> Homo sapien

<400> 2245
 Met Val Val Met Ala Pro Arg Thr Leu Phe Leu Leu Leu Ser Gly
   1               5                  10                  15

 Ala Leu Thr Leu Thr Glu Thr Trp Ala Gly Ser His Ser Met Arg
                  20                  25                  30

 Tyr Phe Ser Ala Ala Val Ser Arg Pro Gly Arg Gly Glu Pro Arg
                  35                  40                  45

 Phe Ile Ala Met Gly Tyr Val Asp Asp Thr Gln Phe Val Arg Phe
                  50                  55                  60

 Asp Ser Asp Ser Ala Cys Pro Arg Met Glu Pro Arg Ala Pro Trp
                  65                  70                  75

 Val Glu Gln Glu Gly Pro Glu Tyr Trp Glu Glu Glu Thr Arg Asn
                  80                  85                  90

 Thr Lys Ala His Ala Gln Thr Asp Arg Met Asn Leu Gln Thr Leu
                  95                 100                 105

 Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Ser Ser His Thr Leu Gln
                 110                 115                 120

 Trp Met Ile Gly Cys Asp Leu Gly Ser Asp Gly Arg Leu Leu Arg
                 125                 130                 135

 Gly Tyr Glu Gln Tyr Ala Tyr Asp Gly Lys Asp Tyr Leu Ala Leu
                 140                 145                 150

 Asn Glu Asp Leu Arg Ser Trp Thr Ala Ala Asp Thr Ala Ala Gln
                 155                 160                 165

 Ile Ser Lys Arg Lys Cys Glu Ala Ala Asn Val Ala Glu Gln Arg
                 170                 175                 180

 Arg Ala Tyr Leu Glu Gly Thr Cys Val Glu Trp Leu His Arg Tyr
                 185                 190                 195

 Leu Glu Asn Gly Lys Glu Met Leu Gln Arg Ala Asp Pro Pro Lys
                 200                 205                 210

 Thr His Val Thr His His Pro Val Phe Asp Tyr Glu Ala Thr Leu
                 215                 220                 225

 Arg Cys Trp Ala Leu Gly Phe Tyr Pro Ala Glu Ile Ile Leu Thr
                 230                 235                 240

 Trp Gln Arg Asp Gly Glu Asp Gln Thr Gln Asp Val Glu Leu Val
                 245                 250                 255

 Glu Thr Arg Pro Ala Gly Asp Gly Thr Phe Gln Lys Trp Ala Ala
                 260                 265                 270

 Val Val Val Pro Ser Gly Glu Glu Gln Arg Tyr Thr Cys His Val
                 275                 280                 285

 Gln His Glu Gly Leu Pro Glu Pro Leu Met Leu Arg Trp Lys Gln
                 290                 295                 300

 Ser Ser Leu Pro Thr Ile Pro Ile Met Gly Ile Val Ala Gly Leu
                 305                 310                 315

 Val Val Leu Ala Ala Val Val Thr Gly Ala Ala Val Ala Ala Val
                 320                 325                 330

 Leu Trp Arg Lys Lys Ser Ser Asp
                 335

<210> 2246
<211> 1071
<212> DNA
<213> Homo sapien

<400> 2246
 gtccatcttg ctgctgtcca ctttgggttc catcttgggc tccatcttgc 50

 tctcacgatt aaaagcttct ttcctgcttt ccccattccg accatcattt 100

 gcaccccggt tctccccatg ccggcctgcg cttcctccat gtctgttctc 150

 cccgtgccga tggccatcag tatgacggct gctgctttct ggatggcggt 200

 atccatctcc atggcgacca ccatctccgt gacgtggact atcgctatgc 250

 cgattgccag tctctccgtg actgtgacgg ctgctgcccc ggttctcagt 300

 atatctctct cttttcccgt tgctgccccc agtcccttct cggctgttat 350

 tccctgaagc tgtgttgttg actccttggg ctccggcaga cgggtaggtc 400

 acaggggcac cactgatgtt gccagtattg ccaaagcctg ggatgccctt 450

 ggcggcactg gtgacggggc tgtcaggact gttatggccc tgttgtgctg 500

 agttagttgg aacagaattc aagctccctg cactagtcca cctgccccac 550

 tgcttcttcg cttctctctt ggaaagtcca gtctctcctc ggcttgcaat 600

 ggaccccaac tgctcctgcg ccgctggtgt ctcctgcacc tgcgctggtt 650

 cctgcaagtg caaagagtgc aaatgcacct cctgcaagaa gagctgctgc 700

 tcctgctgcc ccgtgggctg tagcaagtgt gcccagggct gtgtttgcaa 750

 aggggcgtca gagaagtgca gctgctgcga ctgatgccag gacaaccttt 800

 ctcccagatg taaacagaga gacatgtaca aacctggatt ttttttttat 850

 accaccttga cccatttgct acattccttt tcctgtgaaa tatgtgagtg 900

 ataattaaac actttagacc tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa 950

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1000

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1050

 aaaaaaaaaa aaaaaaaaaa a 1071

<210> 2247
<211> 122
<212> PRT
<213> Homo sapien

<400> 2247
 Met Leu Pro Val Leu Pro Lys Pro Gly Met Pro Leu Ala Ala Leu
   1               5                  10                  15

 Val Thr Gly Leu Ser Gly Leu Leu Trp Pro Cys Cys Ala Glu Leu
                  20                  25                  30

 Val Gly Thr Glu Phe Lys Leu Pro Ala Leu Val His Leu Pro His
                  35                  40                  45

 Cys Phe Phe Ala Ser Leu Leu Glu Ser Pro Val Ser Pro Arg Leu
                  50                  55                  60

 Ala Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Val Ser Cys Thr
                  65                  70                  75

 Cys Ala Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys
                  80                  85                  90

 Lys Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ser Lys Cys
                  95                 100                 105

 Ala Gln Gly Cys Val Cys Lys Gly Ala Ser Glu Lys Cys Ser Cys
                 110                 115                 120

 Cys Asp


<210> 2248
<211> 1578
<212> DNA
<213> Homo sapien

<400> 2248
 ggcgttcctg ttacctctca tcattgtgtt aatggtgaag cacagcgatt 50

 cccggacgca ctctctgaga tattttcgcc tgggcgtttc ggatcccatc 100

 catggggtcc ctgaatttat ttcggttggg tacgtggact cgcaccctat 150

 caccacatat gacagtgtca ctcggcagaa ggagccacgg gccccatgga 200

 tggcagagaa cctcgcgcct gatcactggg agaggtacac tcagctgctg 250

 aggggctggc agcagatgtt caaggtggaa ctgaagcgcc tacagaggca 300

 ctacaatcac tcagggtctc acacttacca gagaatgatt ggctgtgagc 350

 tgctggagga tggaagcacc acaggatttc tgcagtatgc atatgacggg 400

 caggatttcc tgatcttcaa taaagacacc ctctcctggc tggctgtaga 450

 taatgtggct cacaccatca agcaggcatg ggaggccaat cagcatgagt 500

 tgctgtatca aaagaattgg ctggaagaag aatgtattgc ctggctaaag 550

 agattcctgg agtatgggaa agacacccta caaagaacag gtaaagagaa 600

 agagaaggcc tcattcccac attgcctgaa caactgtttt tatacgtaac 650

 tcttttaatc taggttatat ccactgtatc ctgaaagcca tctctttagt 700

 tggcctattg tgatctcatg gctagagccc ccacgaaaac tttccctggt 750

 tacttttgag cagcatcttg acaagatttg acagttcccc ttgtcttgac 800

 agagtggagt acctccaagg gcaccttgtt tttagggatc tattgaggca 850

 aattcttcca ttccgtcaat gataagctgg gaaattcttt gggagataga 900

 gcaattctta caaactgttt agttaacaaa gggctcacac accaccagta 950

 ggagtaaaaa tctggattta ccaagacaaa cagaaggtct ctgctttact 1000

 aaaggattaa tgaggttggg catgatggct catgcctgta atcctagcac 1050

 tttgggaggc tgaggcagga ggattgctta aggccaggag tttaagactg 1100

 gcctgggtaa cattgtgaga ccctgtctct attaaaaaaa aaattagctg 1150

 agcatggtgg cacatgactg tagtcccaga tactcaggag gctgaggtgg 1200

 gaggatctct tgagcctgga aggtcaaggc tgcagtgagc catgatcatg 1250

 atcagcctgg gtcacagagc aagaccctat ttaaaaaaaa aaaaaagtat 1300

 taatgataag attcctttca gcaaagagct cctcttatac cttaaagata 1350

 tgattcagtt ggtcaacttt tagttcatat agaacttttc atgtatgatc 1400

 ttgttattca aaattaatca cacctgtatg atgctacagg aaactcctag 1450

 atacaatgtg tgtgggaaga gtatgggaag ctcccctctc caggcctctg 1500

 tctacattca gtgtcctaat ggattttcaa ccttttggtc aaaacacact 1550

 cctaaaaaaa caaacaaaaa aaaaaaaa 1578

<210> 2249
<211> 205
<212> PRT
<213> Homo sapien

<400> 2249
 Met Val Lys His Ser Asp Ser Arg Thr His Ser Leu Arg Tyr Phe
   1               5                  10                  15

 Arg Leu Gly Val Ser Asp Pro Ile His Gly Val Pro Glu Phe Ile
                  20                  25                  30

 Ser Val Gly Tyr Val Asp Ser His Pro Ile Thr Thr Tyr Asp Ser
                  35                  40                  45

 Val Thr Arg Gln Lys Glu Pro Arg Ala Pro Trp Met Ala Glu Asn
                  50                  55                  60

 Leu Ala Pro Asp His Trp Glu Arg Tyr Thr Gln Leu Leu Arg Gly
                  65                  70                  75

 Trp Gln Gln Met Phe Lys Val Glu Leu Lys Arg Leu Gln Arg His
                  80                  85                  90

 Tyr Asn His Ser Gly Ser His Thr Tyr Gln Arg Met Ile Gly Cys
                  95                 100                 105

 Glu Leu Leu Glu Asp Gly Ser Thr Thr Gly Phe Leu Gln Tyr Ala
                 110                 115                 120

 Tyr Asp Gly Gln Asp Phe Leu Ile Phe Asn Lys Asp Thr Leu Ser
                 125                 130                 135

 Trp Leu Ala Val Asp Asn Val Ala His Thr Ile Lys Gln Ala Trp
                 140                 145                 150

 Glu Ala Asn Gln His Glu Leu Leu Tyr Gln Lys Asn Trp Leu Glu
                 155                 160                 165

 Glu Glu Cys Ile Ala Trp Leu Lys Arg Phe Leu Glu Tyr Gly Lys
                 170                 175                 180

 Asp Thr Leu Gln Arg Thr Gly Lys Glu Lys Glu Lys Ala Ser Phe
                 185                 190                 195

 Pro His Cys Leu Asn Asn Cys Phe Tyr Thr
                 200                 205

<210> 2250
<211> 2167
<212> DNA
<213> Homo sapien

<400> 2250
 actgtgttcc aatgtgccac ggaactcacg cagtggcact ttgtggcttc 50

 atgaaggaag aggcaggcca cgcaacactt cctccccaag ccaaggagaa 100

 gtatcacttt tagaggcaga ggagcggaag gcagtgggtg tgaccaaaag 150

 tgccatttgt taaagactgt tggagcagaa ctactgagaa aaaccaggca 200

 ttgtatcttc agttgtcatc aagttcgcaa tcagattgga aaagctcaac 250

 ttgaagcttt cttgcctgca gtgaagcaga gagatagata ttattcacgt 300

 aataaaaaac atgggcttca acctgacttt ccacctttcc tacaaattcc 350

 gattactgtt gctgttgact ttgtgcctga cagtggttgg gtgggccacc 400

 agtaactact tcgtgggtgc cattcaagag attcctaaag caaaggagtt 450

 catggctaat ttccataaga ccctcatttt ggggaaggga aaaactctga 500

 ctaatgaagc atccacgaag aaggtagaac ttgacaactg cccttctgtg 550

 tctccttacc tcagaggcca gagcaagctc attttcaaac cagatctcac 600

 tttggaagag gtacaggcag aaaatcccaa agtgtccaga ggccggtatc 650

 gccctcagga atgtaaagct ttacagaggg tcgccatcct cgttccccac 700

 cggaacagag agaaacacct gatgtacctg ctggaacatc tgcatccctt 750

 cctgcagagg cagcagctgg attatggcat ctacgtcatc caccaggctg 800

 aaggtaaaaa gtttaatcga gccaaactct tgaatgtggg ctatctagaa 850

 gccctcaagg aagaaaattg ggactgcttt atattccacg atgtggacct 900

 ggtacccgag aatgacttta acctttacaa gtgtgaggag catcccaagc 950

 atctggtggt tggcaggaac agcactgggt acaggttacg ttacagtgga 1000

 tattttgggg gtgttactgc cctaagcaga gagcagtttt tcaaggtgaa 1050

 tggattctct aacaactact ggggatgggg aggcgaagac gatgacctca 1100

 gactcagggt tgagctccaa agaatgaaaa tttcccggcc cctgcctgaa 1150

 gtgggtaaat atacaatggt cttccacact agagacaaag gcaatgaggt 1200

 gaacgcagaa cggatgaagc tcttacacca agtgtcacga gtctggagaa 1250

 cagatgggtt gagtagttgt tcttataaat tagtatctgt ggaacacaat 1300

 cctttatata tcaacatcac agtggatttc tggtttggtg catgaccctg 1350

 gatcttttgg tgatgtttgg aagactgatt ctttgtttgc aataattttg 1400

 gcctagagac ttcaaatagt agcacacatt aagaacctgt tacagctcat 1450

 tgttgagctg aatttttcct ttttgtattt tcttagcaga gctcctggtg 1500

 atgtagagta taaaacagtt gtaacaagac agctttctta gtcattttga 1550

 tcatgagggt taaatattgt aatatggata cttgaaggac tttatataaa 1600

 aggatgactc caaaggataa aatgaacgct atttgaggac tccggttgaa 1650

 ggagatttat ttaaatttga agtaatatat tatgggataa aaggccacag 1700

 gaaataagac tgctgaatgt ctgagagaac cagagttgtt ctcgtccaag 1750

 gtagaaaggt acgaagatac aatactgtta ttcatttatc ctgtacaatc 1800

 atctgtgaag tggtggtgtc aggtgagaag gcgtccacaa aagaggggag 1850

 aaaaggcgac gaatcaggac acagtgaact tgggaatgaa gaggtagcag 1900

 gagggtggag tgtcggctgc aaaggcagca gtagctgagc tggttgcagg 1950

 tgctgatagc cttcagggga ggacctgccc aggtatgcct tccagtgatg 2000

 cccaccagag aatacattct ctattagttt ttaaagagtt tttgtaaaat 2050

 gattttgtac aagtaggata tgaattagca gtttacaagt ttacatatta 2100

 actaataata aatatgtcta tcaaatacct ctgtagtaaa atgtgaaaaa 2150

 gcaaaaaaaa aaaaaaa 2167

<210> 2251
<211> 344
<212> PRT
<213> Homo sapien

<400> 2251
 Met Gly Phe Asn Leu Thr Phe His Leu Ser Tyr Lys Phe Arg Leu
   1               5                  10                  15

 Leu Leu Leu Leu Thr Leu Cys Leu Thr Val Val Gly Trp Ala Thr
                  20                  25                  30

 Ser Asn Tyr Phe Val Gly Ala Ile Gln Glu Ile Pro Lys Ala Lys
                  35                  40                  45

 Glu Phe Met Ala Asn Phe His Lys Thr Leu Ile Leu Gly Lys Gly
                  50                  55                  60

 Lys Thr Leu Thr Asn Glu Ala Ser Thr Lys Lys Val Glu Leu Asp
                  65                  70                  75

 Asn Cys Pro Ser Val Ser Pro Tyr Leu Arg Gly Gln Ser Lys Leu
                  80                  85                  90

 Ile Phe Lys Pro Asp Leu Thr Leu Glu Glu Val Gln Ala Glu Asn
                  95                 100                 105

 Pro Lys Val Ser Arg Gly Arg Tyr Arg Pro Gln Glu Cys Lys Ala
                 110                 115                 120

 Leu Gln Arg Val Ala Ile Leu Val Pro His Arg Asn Arg Glu Lys
                 125                 130                 135

 His Leu Met Tyr Leu Leu Glu His Leu His Pro Phe Leu Gln Arg
                 140                 145                 150

 Gln Gln Leu Asp Tyr Gly Ile Tyr Val Ile His Gln Ala Glu Gly
                 155                 160                 165

 Lys Lys Phe Asn Arg Ala Lys Leu Leu Asn Val Gly Tyr Leu Glu
                 170                 175                 180

 Ala Leu Lys Glu Glu Asn Trp Asp Cys Phe Ile Phe His Asp Val
                 185                 190                 195

 Asp Leu Val Pro Glu Asn Asp Phe Asn Leu Tyr Lys Cys Glu Glu
                 200                 205                 210

 His Pro Lys His Leu Val Val Gly Arg Asn Ser Thr Gly Tyr Arg
                 215                 220                 225

 Leu Arg Tyr Ser Gly Tyr Phe Gly Gly Val Thr Ala Leu Ser Arg
                 230                 235                 240

 Glu Gln Phe Phe Lys Val Asn Gly Phe Ser Asn Asn Tyr Trp Gly
                 245                 250                 255

 Trp Gly Gly Glu Asp Asp Asp Leu Arg Leu Arg Val Glu Leu Gln
                 260                 265                 270

 Arg Met Lys Ile Ser Arg Pro Leu Pro Glu Val Gly Lys Tyr Thr
                 275                 280                 285

 Met Val Phe His Thr Arg Asp Lys Gly Asn Glu Val Asn Ala Glu
                 290                 295                 300

 Arg Met Lys Leu Leu His Gln Val Ser Arg Val Trp Arg Thr Asp
                 305                 310                 315

 Gly Leu Ser Ser Cys Ser Tyr Lys Leu Val Ser Val Glu His Asn
                 320                 325                 330

 Pro Leu Tyr Ile Asn Ile Thr Val Asp Phe Trp Phe Gly Ala
                 335                 340

<210> 2252
<211> 4005
<212> DNA
<213> Homo sapien

<400> 2252
 cggctgcggt tcctggtgct gctcggcgcg cggccagctt tcggaacgga 50

 acgctcggcg tcgcgggccc cgcccggaaa gtttgccgtg gagtcgcgac 100

 ctcttggccc gcgcggcccg gcatgaagcg gcgttgagga gctgctgccg 150

 ccgcttgccg ctgccgccgc cgccgcctga ggaggagctg cagcaccctg 200

 ggccacgccg atgactactg caaactgtgg cgcccacgac gagctcgact 250

 tcaaactcgt ctttggcgag gacggggcgc cggcgccgcc gcccccgggc 300

 tcgcggcctg cagatcttga gccagatgat tgtgcatcca tttacatctt 350

 taatgtagat ccacctccat ctactttaac cacaccactt tgcttaccac 400

 atcatggatt accgtctcac tcttctgttt tgtcaccatc gtttcagctc 450

 caaagtcaca aaaactatga aggaacttgt gagattcctg aatctaaata 500

 tagcccatta ggtggtccca aaccctttga gtgcccaagt attcaaatta 550

 catctatctc tcctaactgt catcaagaat tagatgcaca tgaagatgac 600

 ctacagataa atgacccaga acgggaattt ttggaaaggc cttctagaga 650

 tcatctctat cttcctcttg agccatccta ccgggagtct tctcttagtc 700

 ctagtcctgc cagcagcatc tcttctagga gttggttctc tgatgcatct 750

 tcttgtgaat cgctttcaca tatttatgat gatgtggact cagagttgaa 800

 tgaagctgca gcccgattta cccttggatc ccctctgact tctcctggtg 850

 gctctccagg gggctgccct ggagaagaaa cttggcatca acagtatgga 900

 cttggacact cattatcacc caggcaatct ccttgccact ctcctagatc 950

 cagtgtcact gatgagaatt ggctgagccc caggccagcc tcaggaccct 1000

 catcaaggcc cacatccccc tgtgggaaac ggaggcactc cagtgctgaa 1050

 gtttgttatg ctgggtccct ttcaccccat cactcacctg ttccttcacc 1100

 tggtcactcc cccaggggaa gtgtgacaga agatacgtgg ctcaatgctt 1150

 ctgtccatgg tgggtcaggc cttggccctg cagtttttcc atttcagtac 1200

 tgtgtagaga ctgacatccc tctcaaaaca aggaaaactt ctgaagatca 1250

 agctgccata ctaccaggaa aattagagct gtgttcagat gaccaaggga 1300

 gtttatcacc agcccgggag acttcaatag atgatggcct tggatctcag 1350

 tatcctttaa agaaagattc atgtggtgat cagtttcttt cagttccttc 1400

 accctttacc tggagcaaac caaagcctgg ccacacccct atatttcgca 1450

 catcttcatt acctccacta gactggcctt taccagctca ttttggacaa 1500

 tgtgaactga aaatagaagt gcaacctaaa actcatcatc gagcccatta 1550

 tgaaactgaa ggtagccgag gggcagtaaa agcatctact gggggacatc 1600

 ctgttgtgaa gctcctgggc tataacgaaa agccaataaa tctacaaatg 1650

 tttattggga cagcagatga tcgatattta cgacctcatg cattttacca 1700

 ggtgcatcga atcactggga agacagtcgc tactgcaagc caagagataa 1750

 taattgccag tacaaaagtt ctggaaattc cacttcttcc tgaaaataat 1800

 atgtcagcca gtattgattg tgcaggtatt ttgaaactcc gcaattcaga 1850

 tatagaactt cgaaaaggag aaactgatat tggcagaaag aatactagag 1900

 tacgacttgt gtttcgtgta cacatcccac agcccagtgg aaaagtcctt 1950

 tctctgcaga tagcctctat acccgttgag tgctcccagc ggtctgctca 2000

 agaacttcct catattgaga agtacagtat caacagttgt tctgtaaatg 2050

 gaggtcatga aatggttgtg actggatcta attttcttcc agaatccaaa 2100

 atcatttttc ttgaaaaagg acaagatgga cgacctcagt gggaggtaga 2150

 agggaagata atcagggaaa aatgtcaagg ggctcacatt gtccttgaag 2200

 ttcctccata tcataaccca gcagttacag ctgcagtgca ggtgcacttt 2250

 tatctttgca atggcaagag gaaaaaaagc cagtctcaac gttttactta 2300

 tacaccagtt ttgatgaagc aagaacacag agaagagatt gatttgtctt 2350

 cagttccatc tttgcctgtg cctcatcctg ctcagaccca gaggccttcc 2400

 tctgattcag ggtgttcaca tgacagtgta ctgtcaggac agagaagttt 2450

 gatttgctcc atcccacaaa catatgcatc catggtgacc tcatcccatc 2500

 tgccacagtt gcagtgtaga gatgagagtg ttagtaaaga acagcatatg 2550

 attccttctc caattgtaca ccagcctttt caagtcacac caacacctcc 2600

 tgtggggtct tcctatcagc ctatgcaaac taatgttgtg tacaatggac 2650

 caacttgtct tcctattaat gctgcctcta gtcaagaatt tgattcagtt 2700

 ttgtttcagc aggatgcaac tctttctggt ttagtgaatc ttggctgtca 2750

 accactgtca tccataccat ttcattcttc aaattcaggc tcaacaggac 2800

 atctcttagc ccatacacct cattctgtgc ataccctgcc tcatctgcaa 2850

 tcaatgggat atcattgttc aaatacagga caaagatctc tttcttctcc 2900

 agtggctgac cagattacag gtcagccttc gtctcagtta caacctatta 2950

 catatggtcc ttcacattca gggtctgcta caacagcttc cccagcagct 3000

 tctcatccct tggctagttc accgctttct gggccaccat ctcctcagct 3050

 tcagcctatg ccttaccaat ctcctagctc aggaactgcc tcatcaccgt 3100

 ctccagccac cagaatgcat tctggacagc actcaactca agcacaaagt 3150

 acgggccagg ggggtctttc tgcaccttca tccttaatat gtcacagttt 3200

 gtgtgatcca gcgtcatttc cacctgatgg ggcaactgtg agcattaaac 3250

 ctgaaccaga agatcgagag cctaactttg caaccattgg tctgcaggac 3300

 atcactttag atgatgacca atttatatct gacttggaac accagccatc 3350

 aggttcagca gagaaatggc ctaaccacag tgtgctctca tgtccagctc 3400

 ctttctggag aatctagagg tgaacgagat aattgggaga gacatgtccc 3450

 agatttctgt ttcccaagga gcaggggtga gcaggcaggc tcccctcccg 3500

 agtcctgagt ccctggattt aggaagatct gatgggctct aacagtgctt 3550

 actgcagcct tgtgtccacc accaacttct cagcatgttt ctctccttgg 3600

 accttgggtt tccaactctg cagccttcag gtctggggcc aggagtggga 3650

 cccaccattt gtggggaaag tagcattcct ccacctcagg ccttgggtag 3700

 atttggcaaa agaacaggag cagcataggc tgtttgagct ttggggaaat 3750

 gaactttgct ttttatattt aactaggata cttttatatg atgggtgctt 3800

 tgagtgtgaa tgcagcaggc tctcttgttt ccgaggtgct gcttttgcag 3850

 gtgacctggt tacttagcta ggattggtga tttgtactgc tttatggtca 3900

 tttgaagggc cctttagttt ttatgataat ttttaaaata ggaacttttg 3950

 ataagacctt ctagaagcaa aaaaaaaaaa aaaaaaaaaa aaaagaaaaa 4000

 aaaag 4005

<210> 2253
<211> 1068
<212> PRT
<213> Homo sapien

<400> 2253
 Met Thr Thr Ala Asn Cys Gly Ala His Asp Glu Leu Asp Phe Lys
   1               5                  10                  15

 Leu Val Phe Gly Glu Asp Gly Ala Pro Ala Pro Pro Pro Pro Gly
                  20                  25                  30

 Ser Arg Pro Ala Asp Leu Glu Pro Asp Asp Cys Ala Ser Ile Tyr
                  35                  40                  45

 Ile Phe Asn Val Asp Pro Pro Pro Ser Thr Leu Thr Thr Pro Leu
                  50                  55                  60

 Cys Leu Pro His His Gly Leu Pro Ser His Ser Ser Val Leu Ser
                  65                  70                  75

 Pro Ser Phe Gln Leu Gln Ser His Lys Asn Tyr Glu Gly Thr Cys
                  80                  85                  90

 Glu Ile Pro Glu Ser Lys Tyr Ser Pro Leu Gly Gly Pro Lys Pro
                  95                 100                 105

 Phe Glu Cys Pro Ser Ile Gln Ile Thr Ser Ile Ser Pro Asn Cys
                 110                 115                 120

 His Gln Glu Leu Asp Ala His Glu Asp Asp Leu Gln Ile Asn Asp
                 125                 130                 135

 Pro Glu Arg Glu Phe Leu Glu Arg Pro Ser Arg Asp His Leu Tyr
                 140                 145                 150

 Leu Pro Leu Glu Pro Ser Tyr Arg Glu Ser Ser Leu Ser Pro Ser
                 155                 160                 165

 Pro Ala Ser Ser Ile Ser Ser Arg Ser Trp Phe Ser Asp Ala Ser
                 170                 175                 180

 Ser Cys Glu Ser Leu Ser His Ile Tyr Asp Asp Val Asp Ser Glu
                 185                 190                 195

 Leu Asn Glu Ala Ala Ala Arg Phe Thr Leu Gly Ser Pro Leu Thr
                 200                 205                 210

 Ser Pro Gly Gly Ser Pro Gly Gly Cys Pro Gly Glu Glu Thr Trp
                 215                 220                 225

 His Gln Gln Tyr Gly Leu Gly His Ser Leu Ser Pro Arg Gln Ser
                 230                 235                 240

 Pro Cys His Ser Pro Arg Ser Ser Val Thr Asp Glu Asn Trp Leu
                 245                 250                 255

 Ser Pro Arg Pro Ala Ser Gly Pro Ser Ser Arg Pro Thr Ser Pro
                 260                 265                 270

 Cys Gly Lys Arg Arg His Ser Ser Ala Glu Val Cys Tyr Ala Gly
                 275                 280                 285

 Ser Leu Ser Pro His His Ser Pro Val Pro Ser Pro Gly His Ser
                 290                 295                 300

 Pro Arg Gly Ser Val Thr Glu Asp Thr Trp Leu Asn Ala Ser Val
                 305                 310                 315

 His Gly Gly Ser Gly Leu Gly Pro Ala Val Phe Pro Phe Gln Tyr
                 320                 325                 330

 Cys Val Glu Thr Asp Ile Pro Leu Lys Thr Arg Lys Thr Ser Glu
                 335                 340                 345

 Asp Gln Ala Ala Ile Leu Pro Gly Lys Leu Glu Leu Cys Ser Asp
                 350                 355                 360

 Asp Gln Gly Ser Leu Ser Pro Ala Arg Glu Thr Ser Ile Asp Asp
                 365                 370                 375

 Gly Leu Gly Ser Gln Tyr Pro Leu Lys Lys Asp Ser Cys Gly Asp
                 380                 385                 390

 Gln Phe Leu Ser Val Pro Ser Pro Phe Thr Trp Ser Lys Pro Lys
                 395                 400                 405

 Pro Gly His Thr Pro Ile Phe Arg Thr Ser Ser Leu Pro Pro Leu
                 410                 415                 420

 Asp Trp Pro Leu Pro Ala His Phe Gly Gln Cys Glu Leu Lys Ile
                 425                 430                 435

 Glu Val Gln Pro Lys Thr His His Arg Ala His Tyr Glu Thr Glu
                 440                 445                 450

 Gly Ser Arg Gly Ala Val Lys Ala Ser Thr Gly Gly His Pro Val
                 455                 460                 465

 Val Lys Leu Leu Gly Tyr Asn Glu Lys Pro Ile Asn Leu Gln Met
                 470                 475                 480

 Phe Ile Gly Thr Ala Asp Asp Arg Tyr Leu Arg Pro His Ala Phe
                 485                 490                 495

 Tyr Gln Val His Arg Ile Thr Gly Lys Thr Val Ala Thr Ala Ser
                 500                 505                 510

 Gln Glu Ile Ile Ile Ala Ser Thr Lys Val Leu Glu Ile Pro Leu
                 515                 520                 525

 Leu Pro Glu Asn Asn Met Ser Ala Ser Ile Asp Cys Ala Gly Ile
                 530                 535                 540

 Leu Lys Leu Arg Asn Ser Asp Ile Glu Leu Arg Lys Gly Glu Thr
                 545                 550                 555

 Asp Ile Gly Arg Lys Asn Thr Arg Val Arg Leu Val Phe Arg Val
                 560                 565                 570

 His Ile Pro Gln Pro Ser Gly Lys Val Leu Ser Leu Gln Ile Ala
                 575                 580                 585

 Ser Ile Pro Val Glu Cys Ser Gln Arg Ser Ala Gln Glu Leu Pro
                 590                 595                 600

 His Ile Glu Lys Tyr Ser Ile Asn Ser Cys Ser Val Asn Gly Gly
                 605                 610                 615

 His Glu Met Val Val Thr Gly Ser Asn Phe Leu Pro Glu Ser Lys
                 620                 625                 630

 Ile Ile Phe Leu Glu Lys Gly Gln Asp Gly Arg Pro Gln Trp Glu
                 635                 640                 645

 Val Glu Gly Lys Ile Ile Arg Glu Lys Cys Gln Gly Ala His Ile
                 650                 655                 660

 Val Leu Glu Val Pro Pro Tyr His Asn Pro Ala Val Thr Ala Ala
                 665                 670                 675

 Val Gln Val His Phe Tyr Leu Cys Asn Gly Lys Arg Lys Lys Ser
                 680                 685                 690

 Gln Ser Gln Arg Phe Thr Tyr Thr Pro Val Leu Met Lys Gln Glu
                 695                 700                 705

 His Arg Glu Glu Ile Asp Leu Ser Ser Val Pro Ser Leu Pro Val
                 710                 715                 720

 Pro His Pro Ala Gln Thr Gln Arg Pro Ser Ser Asp Ser Gly Cys
                 725                 730                 735

 Ser His Asp Ser Val Leu Ser Gly Gln Arg Ser Leu Ile Cys Ser
                 740                 745                 750

 Ile Pro Gln Thr Tyr Ala Ser Met Val Thr Ser Ser His Leu Pro
                 755                 760                 765

 Gln Leu Gln Cys Arg Asp Glu Ser Val Ser Lys Glu Gln His Met
                 770                 775                 780

 Ile Pro Ser Pro Ile Val His Gln Pro Phe Gln Val Thr Pro Thr
                 785                 790                 795

 Pro Pro Val Gly Ser Ser Tyr Gln Pro Met Gln Thr Asn Val Val
                 800                 805                 810

 Tyr Asn Gly Pro Thr Cys Leu Pro Ile Asn Ala Ala Ser Ser Gln
                 815                 820                 825

 Glu Phe Asp Ser Val Leu Phe Gln Gln Asp Ala Thr Leu Ser Gly
                 830                 835                 840

 Leu Val Asn Leu Gly Cys Gln Pro Leu Ser Ser Ile Pro Phe His
                 845                 850                 855

 Ser Ser Asn Ser Gly Ser Thr Gly His Leu Leu Ala His Thr Pro
                 860                 865                 870

 His Ser Val His Thr Leu Pro His Leu Gln Ser Met Gly Tyr His
                 875                 880                 885

 Cys Ser Asn Thr Gly Gln Arg Ser Leu Ser Ser Pro Val Ala Asp
                 890                 895                 900

 Gln Ile Thr Gly Gln Pro Ser Ser Gln Leu Gln Pro Ile Thr Tyr
                 905                 910                 915

 Gly Pro Ser His Ser Gly Ser Ala Thr Thr Ala Ser Pro Ala Ala
                 920                 925                 930

 Ser His Pro Leu Ala Ser Ser Pro Leu Ser Gly Pro Pro Ser Pro
                 935                 940                 945

 Gln Leu Gln Pro Met Pro Tyr Gln Ser Pro Ser Ser Gly Thr Ala
                 950                 955                 960

 Ser Ser Pro Ser Pro Ala Thr Arg Met His Ser Gly Gln His Ser
                 965                 970                 975

 Thr Gln Ala Gln Ser Thr Gly Gln Gly Gly Leu Ser Ala Pro Ser
                 980                 985                 990

 Ser Leu Ile Cys His Ser Leu Cys Asp Pro Ala Ser Phe Pro Pro
                 995                1000                1005

 Asp Gly Ala Thr Val Ser Ile Lys Pro Glu Pro Glu Asp Arg Glu
                1010                1015                1020

 Pro Asn Phe Ala Thr Ile Gly Leu Gln Asp Ile Thr Leu Asp Asp
                1025                1030                1035

 Asp Gln Phe Ile Ser Asp Leu Glu His Gln Pro Ser Gly Ser Ala
                1040                1045                1050

 Glu Lys Trp Pro Asn His Ser Val Leu Ser Cys Pro Ala Pro Phe
                1055                1060                1065

 Trp Arg Ile


<210> 2254
<211> 3769
<212> DNA
<213> Homo sapien

<400> 2254
 cggctgcggt tcctggtgct gctcggcgcg cggccagctt tcggaacgga 50

 acgctcggcg tcgcgggccc cgcccggaaa gtttgccgtg gagtcgcgac 100

 ctcttggccc gcgcggcccg gcatgaagcg gcgttgagga gctgctgccg 150

 ccgcttgccg ctgccgccgc cgccgcctga ggaggagctg cagcaccctg 200

 ggccacgccg atgactactg caaactgtgg cgcccacgac gagctcgact 250

 tcaaactcgt ctttggcgag gacggggcgc cggcgccgcc gcccccgggc 300

 tcgcggcctg cagatcttga gccagatgat tgtgcatcca tttacatctt 350

 taatgtagat ccacctccat ctactttaac cacaccactt tgcttaccac 400

 atcatggatt accgtctcac tcttctgttt tgtcaccatc gtttcagctc 450

 caaagtcaca aaaactatga aggaacttgt gagattcctg aatctaaata 500

 tagcccatta ggtggtccca aaccctttga gtgcccaagt attcaaatta 550

 catctatctc tcctaactgt catcaagaat tagatgcaca tgaagatgac 600

 ctacagataa atgacccaga acgggaattt ttggaaaggc cttctagaga 650

 tcatctctat cttcctcttg agccatccta ccgggagtct tctcttagtc 700

 ctagtcctgc cagcagcatc tcttctagga gttggttctc tgatgcatct 750

 tcttgtgaat cgctttcaca tatttatgat gatgtggact cagagttgaa 800

 tgaagctgca gcccgattta cccttggatc ccctctgact tctcctggtg 850

 gctctccagg gggctgccct ggagaagaaa cttggcatca acagtatgga 900

 cttggacact cattatcacc caggcaatct ccttgccact ctcctagatc 950

 cagtgtcact gatgagaatt ggctgagccc caggccagcc tcaggaccct 1000

 catcaaggcc cacatccccc tgtgggaaac ggaggcactc cagtgctgaa 1050

 gtttgttatg ctgggtccct ttcaccccat cactcacctg ttccttcacc 1100

 tggtcactcc cccaggggaa gtgtgacaga agatacgtgg ctcaatgctt 1150

 ctgtccatgg tgggtcaggc cttggccctg cagtttttcc atttcagtac 1200

 tgtgtagaga ctgacatccc tctcaaaaca aggaaaactt ctgaagatca 1250

 agctgccata ctaccaggaa aattagagct gtgttcagat gaccaaggga 1300

 gtttatcacc agcccgggag acttcaatag atgatggcct tggatctcag 1350

 tatcctttaa agaaagattc atgtggtgat cagtttcttt cagttccttc 1400

 accctttacc tggagcaaac caaagcctgg ccacacccct atatttcgca 1450

 catcttcatt acctccacta gactggcctt taccagctca ttttggacaa 1500

 tgtgaactga aaatagaagt gcaacctaaa actcatcatc gagcccatta 1550

 tgaaactgaa ggtagccgag gggcagtaaa agcatctact gggggacatc 1600

 ctgttgtgaa gctcctgggc tataacgaaa agccaataaa tctacaaatg 1650

 tttattggga cagcagatga tcgatattta cgacctcatg cattttacca 1700

 ggtgcatcga atcactggga agacagtcgc tactgcaagc caagagataa 1750

 taattgccag tacaaaagtt ctggaaattc cacttcttcc tgaaaataat 1800

 atgtcagcca gtattgattg tgcaggtatt ttgaaactcc gcaattcaga 1850

 tatagaactt cgaaaaggag aaactgatat tggcagaaag aatactagag 1900

 tacgacttgt gtttcgtgta cacatcccac agcccagtgg aaaagtcctt 1950

 tctctgcaga tagcctctat acccgttgag tgctcccagc ggtctgctca 2000

 agaacttcct catattgaga agtacagtat caacagttgt tctgtaaatg 2050

 gaggtcatga aatggttgtg actggatcta attttcttcc agaatccaaa 2100

 atcatttttc ttgaaaaagg acaagatgga cgacctcagt gggaggtaga 2150

 agggaagata atcagggaaa aatgtcaagg ggctcacatt gtccttgaag 2200

 ttcctccata tcataaccca gcagttacag ctgcagtgca ggtgcacttt 2250

 tatctttgca atggcaagag gaaaaaaagc cagtctcaac gttttactta 2300

 tacaccagtt ttgatgaagc aagaacacag agaagagatt gatttgtctt 2350

 cagttccatc tttgcctgtg cctcatcctg ctcagaccca gaggccttcc 2400

 tctgattcag ggtgttcaca tgacagtgta ctgtcaggac agagaagttt 2450

 gatttgctcc atcccacaaa catatgcatc catggtgacc tcatcccatc 2500

 tgccacagtt gcagtgtaga gatgagagtg ttagtaaaga acagcatatg 2550

 attccttctc caattgtaca ccagcctttt caagtcacac caacacctcc 2600

 tgtggggtct tcctatcagc ctatgcaaac taatgttgtg tacaatggac 2650

 caacttgtct tcctattaat gctgcctcta gtcaagaatt tgattcagtt 2700

 ttgtttcagc aggatgcaac tctttctggt ttagtgaatc ttggctgtca 2750

 accactgtca tccataccat ttcattcttc aaattcaggc tcaacaggac 2800

 atctcttagc ccatacacct cattctgtgc ataccctgcc tcatctgcaa 2850

 tcaatgggat atcattgttc aaatacagga caaagatctc tttcttctcc 2900

 agtggctgac cagattacag gtcagccttc gtctcagtta caacctatta 2950

 catatggtcc ttcacattca gggtctgcta caacagcttc cccagcagct 3000

 tctcatccct tggctagttc accgctttct gggccaccat ctcctcagct 3050

 tcagcctatg ccttaccaat ctcctagctc aggaactgcc tcatcaccgt 3100

 ctccagccac cagaatgcat tctggacagc actcaactca agcacaaagt 3150

 acgggccagg ggggtctttc tgcaccttca tccttaatat gtcacagttt 3200

 gtgtgatcca gcgtcatttc cacctgatgg ggcaactgtg agcattaaac 3250

 ctgaaccaga agatcgagag cctaactttg caaccattgg tctgcaggac 3300

 atcactttag atgatggtaa gttcatctct gatatgttct tgaagtagtg 3350

 aagattcagg gactttattc tcccaagtgt catgaaaaag tttctatgga 3400

 ttgcttattg gcatatggtt gggcttttaa ataagttgtt attagaaata 3450

 tatgttaata tataactttg ccaggtacca cggctcacgc ctgtatccca 3500

 gcactttgga aggctgaggc gggtggatca caaggtcagg agttcaagac 3550

 cagcctggcc aacatggtgt aacgctgtct ctactaaaaa tacaaaaaat 3600

 tagccaggca tggtggtgtg tgactataat cccagctact cgggaggctg 3650

 agacaggaga atcacttgaa cccgggaggt ggcagttgca gggagctaag 3700

 atcgcgccat tgcactccag cctgggcggc agagcaagac tccgtctcgg 3750

 gaaaaaaaaa aaaaaaaaa 3769

<210> 2255
<211> 1045
<212> PRT
<213> Homo sapien

<400> 2255
 Met Thr Thr Ala Asn Cys Gly Ala His Asp Glu Leu Asp Phe Lys
   1               5                  10                  15

 Leu Val Phe Gly Glu Asp Gly Ala Pro Ala Pro Pro Pro Pro Gly
                  20                  25                  30

 Ser Arg Pro Ala Asp Leu Glu Pro Asp Asp Cys Ala Ser Ile Tyr
                  35                  40                  45

 Ile Phe Asn Val Asp Pro Pro Pro Ser Thr Leu Thr Thr Pro Leu
                  50                  55                  60

 Cys Leu Pro His His Gly Leu Pro Ser His Ser Ser Val Leu Ser
                  65                  70                  75

 Pro Ser Phe Gln Leu Gln Ser His Lys Asn Tyr Glu Gly Thr Cys
                  80                  85                  90

 Glu Ile Pro Glu Ser Lys Tyr Ser Pro Leu Gly Gly Pro Lys Pro
                  95                 100                 105

 Phe Glu Cys Pro Ser Ile Gln Ile Thr Ser Ile Ser Pro Asn Cys
                 110                 115                 120

 His Gln Glu Leu Asp Ala His Glu Asp Asp Leu Gln Ile Asn Asp
                 125                 130                 135

 Pro Glu Arg Glu Phe Leu Glu Arg Pro Ser Arg Asp His Leu Tyr
                 140                 145                 150

 Leu Pro Leu Glu Pro Ser Tyr Arg Glu Ser Ser Leu Ser Pro Ser
                 155                 160                 165

 Pro Ala Ser Ser Ile Ser Ser Arg Ser Trp Phe Ser Asp Ala Ser
                 170                 175                 180

 Ser Cys Glu Ser Leu Ser His Ile Tyr Asp Asp Val Asp Ser Glu
                 185                 190                 195

 Leu Asn Glu Ala Ala Ala Arg Phe Thr Leu Gly Ser Pro Leu Thr
                 200                 205                 210

 Ser Pro Gly Gly Ser Pro Gly Gly Cys Pro Gly Glu Glu Thr Trp
                 215                 220                 225

 His Gln Gln Tyr Gly Leu Gly His Ser Leu Ser Pro Arg Gln Ser
                 230                 235                 240

 Pro Cys His Ser Pro Arg Ser Ser Val Thr Asp Glu Asn Trp Leu
                 245                 250                 255

 Ser Pro Arg Pro Ala Ser Gly Pro Ser Ser Arg Pro Thr Ser Pro
                 260                 265                 270

 Cys Gly Lys Arg Arg His Ser Ser Ala Glu Val Cys Tyr Ala Gly
                 275                 280                 285

 Ser Leu Ser Pro His His Ser Pro Val Pro Ser Pro Gly His Ser
                 290                 295                 300

 Pro Arg Gly Ser Val Thr Glu Asp Thr Trp Leu Asn Ala Ser Val
                 305                 310                 315

 His Gly Gly Ser Gly Leu Gly Pro Ala Val Phe Pro Phe Gln Tyr
                 320                 325                 330

 Cys Val Glu Thr Asp Ile Pro Leu Lys Thr Arg Lys Thr Ser Glu
                 335                 340                 345

 Asp Gln Ala Ala Ile Leu Pro Gly Lys Leu Glu Leu Cys Ser Asp
                 350                 355                 360

 Asp Gln Gly Ser Leu Ser Pro Ala Arg Glu Thr Ser Ile Asp Asp
                 365                 370                 375

 Gly Leu Gly Ser Gln Tyr Pro Leu Lys Lys Asp Ser Cys Gly Asp
                 380                 385                 390

 Gln Phe Leu Ser Val Pro Ser Pro Phe Thr Trp Ser Lys Pro Lys
                 395                 400                 405

 Pro Gly His Thr Pro Ile Phe Arg Thr Ser Ser Leu Pro Pro Leu
                 410                 415                 420

 Asp Trp Pro Leu Pro Ala His Phe Gly Gln Cys Glu Leu Lys Ile
                 425                 430                 435

 Glu Val Gln Pro Lys Thr His His Arg Ala His Tyr Glu Thr Glu
                 440                 445                 450

 Gly Ser Arg Gly Ala Val Lys Ala Ser Thr Gly Gly His Pro Val
                 455                 460                 465

 Val Lys Leu Leu Gly Tyr Asn Glu Lys Pro Ile Asn Leu Gln Met
                 470                 475                 480

 Phe Ile Gly Thr Ala Asp Asp Arg Tyr Leu Arg Pro His Ala Phe
                 485                 490                 495

 Tyr Gln Val His Arg Ile Thr Gly Lys Thr Val Ala Thr Ala Ser
                 500                 505                 510

 Gln Glu Ile Ile Ile Ala Ser Thr Lys Val Leu Glu Ile Pro Leu
                 515                 520                 525

 Leu Pro Glu Asn Asn Met Ser Ala Ser Ile Asp Cys Ala Gly Ile
                 530                 535                 540

 Leu Lys Leu Arg Asn Ser Asp Ile Glu Leu Arg Lys Gly Glu Thr
                 545                 550                 555

 Asp Ile Gly Arg Lys Asn Thr Arg Val Arg Leu Val Phe Arg Val
                 560                 565                 570

 His Ile Pro Gln Pro Ser Gly Lys Val Leu Ser Leu Gln Ile Ala
                 575                 580                 585

 Ser Ile Pro Val Glu Cys Ser Gln Arg Ser Ala Gln Glu Leu Pro
                 590                 595                 600

 His Ile Glu Lys Tyr Ser Ile Asn Ser Cys Ser Val Asn Gly Gly
                 605                 610                 615

 His Glu Met Val Val Thr Gly Ser Asn Phe Leu Pro Glu Ser Lys
                 620                 625                 630

 Ile Ile Phe Leu Glu Lys Gly Gln Asp Gly Arg Pro Gln Trp Glu
                 635                 640                 645

 Val Glu Gly Lys Ile Ile Arg Glu Lys Cys Gln Gly Ala His Ile
                 650                 655                 660

 Val Leu Glu Val Pro Pro Tyr His Asn Pro Ala Val Thr Ala Ala
                 665                 670                 675

 Val Gln Val His Phe Tyr Leu Cys Asn Gly Lys Arg Lys Lys Ser
                 680                 685                 690

 Gln Ser Gln Arg Phe Thr Tyr Thr Pro Val Leu Met Lys Gln Glu
                 695                 700                 705

 His Arg Glu Glu Ile Asp Leu Ser Ser Val Pro Ser Leu Pro Val
                 710                 715                 720

 Pro His Pro Ala Gln Thr Gln Arg Pro Ser Ser Asp Ser Gly Cys
                 725                 730                 735

 Ser His Asp Ser Val Leu Ser Gly Gln Arg Ser Leu Ile Cys Ser
                 740                 745                 750

 Ile Pro Gln Thr Tyr Ala Ser Met Val Thr Ser Ser His Leu Pro
                 755                 760                 765

 Gln Leu Gln Cys Arg Asp Glu Ser Val Ser Lys Glu Gln His Met
                 770                 775                 780

 Ile Pro Ser Pro Ile Val His Gln Pro Phe Gln Val Thr Pro Thr
                 785                 790                 795

 Pro Pro Val Gly Ser Ser Tyr Gln Pro Met Gln Thr Asn Val Val
                 800                 805                 810

 Tyr Asn Gly Pro Thr Cys Leu Pro Ile Asn Ala Ala Ser Ser Gln
                 815                 820                 825

 Glu Phe Asp Ser Val Leu Phe Gln Gln Asp Ala Thr Leu Ser Gly
                 830                 835                 840

 Leu Val Asn Leu Gly Cys Gln Pro Leu Ser Ser Ile Pro Phe His
                 845                 850                 855

 Ser Ser Asn Ser Gly Ser Thr Gly His Leu Leu Ala His Thr Pro
                 860                 865                 870

 His Ser Val His Thr Leu Pro His Leu Gln Ser Met Gly Tyr His
                 875                 880                 885

 Cys Ser Asn Thr Gly Gln Arg Ser Leu Ser Ser Pro Val Ala Asp
                 890                 895                 900

 Gln Ile Thr Gly Gln Pro Ser Ser Gln Leu Gln Pro Ile Thr Tyr
                 905                 910                 915

 Gly Pro Ser His Ser Gly Ser Ala Thr Thr Ala Ser Pro Ala Ala
                 920                 925                 930

 Ser His Pro Leu Ala Ser Ser Pro Leu Ser Gly Pro Pro Ser Pro
                 935                 940                 945

 Gln Leu Gln Pro Met Pro Tyr Gln Ser Pro Ser Ser Gly Thr Ala
                 950                 955                 960

 Ser Ser Pro Ser Pro Ala Thr Arg Met His Ser Gly Gln His Ser
                 965                 970                 975

 Thr Gln Ala Gln Ser Thr Gly Gln Gly Gly Leu Ser Ala Pro Ser
                 980                 985                 990

 Ser Leu Ile Cys His Ser Leu Cys Asp Pro Ala Ser Phe Pro Pro
                 995                1000                1005

 Asp Gly Ala Thr Val Ser Ile Lys Pro Glu Pro Glu Asp Arg Glu
                1010                1015                1020

 Pro Asn Phe Ala Thr Ile Gly Leu Gln Asp Ile Thr Leu Asp Asp
                1025                1030                1035

 Gly Lys Phe Ile Ser Asp Met Phe Leu Lys
                1040                1045

<210> 2256
<211> 1855
<212> DNA
<213> Homo sapien

<400> 2256
 gagggctggc cagtgaggct cggcccgggg aaagtgaaag tttgcctggg 50

 tcctctcggc gccagagccg ctctccgcat cccaggacag cggtgcggcc 100

 ctcggccggg gcgcccactc cgcagcagcc agcgagcgag cgagcgagcg 150

 agggcggccg acgcgcccgg ccgggaccca gctgcccgta tgaccgcgcc 200

 gggcgccgcc gggcgctgcc ctcccacgac atggctgggc tccctgctgt 250

 tgttggtctg tctcctggcg agcaggagta tcaccgagga ggtgtcggag 300

 tactgtagcc acatgattgg gagtggacac ctgcagtctc tgcagcggct 350

 gattgacagt cagatggaga cctcgtgcca aattacattt gagtttgtag 400

 accaggaaca gttgaaagat ccagtgtgct accttaagaa ggcatttctc 450

 ctggtacaag acataatgga ggacaccatg cgcttcagag ataacacccc 500

 caatgccatc gccattgtgc agctgcagga actctctttg aggctgaaga 550

 gctgcttcac caaggattat gaagagcatg acaaggcctg cgtccgaact 600

 ttctatgaga cacctctcca gttgctggag aaggtcaaga atgtctttaa 650

 tgaaacaaag aatctccttg acaaggactg gaatattttc agcaagaact 700

 gcaacaacag ctttgctgaa tgctccagcc aaggccatga gaggcagtcc 750

 gagggatcct ccagcccgca gctccaggag tctgtcttcc acctgctggt 800

 gcccagtgtc atcctggtct tgctggccgt cggaggcctc ttgttctaca 850

 ggtggaggcg gcggagccat caagagcctc agagagcgga ttctcccttg 900

 gagcaaccag agggcagccc cctgactcag gatgacagac aggtggaact 950

 gccagtgtag agggaattct aagctggacg cacagaacag tctctccgtg 1000

 ggaggagaca ttatggggcg tccaccacca cccctccctg gccatcctcc 1050

 tggaatgtgg tctgccctcc accagagctc ctgcctgcca ggactggacc 1100

 agagcagcca ggctggggcc cctctgtctc aacccgcaga cccttgactg 1150

 aatgagagag gccagaggat gctccccatg ctgccactat ttattgtgag 1200

 ccctggaggc tcccatgtgc ttgaggaagg ctggtgagcc cggctcagga 1250

 ccctcttccc tcaggggctg caccctcctc tcactccctt ccatgccgga 1300

 acccaggcca gggacccacc ggcctgtggt ttgtgggaaa gcagggtgga 1350

 cgctgaggag tgaaagaacc ctgcacccag agggcctgcc tggtgccaag 1400

 gtatcccagc ctggacaggc atggacctgt ctccagagag aggagcctga 1450

 agttcgtggg gcgggacagc gtcggcctga tttcccgtaa aggtgtgcag 1500

 cctgagagac gggaagagga ggcctctgga cctgctggtc tgcactgaca 1550

 gcctgaaggg tctacaccct cggctcacct aagtgccctg tgctggttgc 1600

 caggcgcaga ggggaggcca gccctgccct caggacctgc ctgacctgcc 1650

 agtgatgcca agagggggat caagcactgg cctctgcccc tcctccttcc 1700

 agcacctgcc agagcttctc caggaggcca agcagaggct cccctcatga 1750

 aggaagccat tgcactgtga acactgtacc tgcctgctga acagcctgcc 1800

 cccgtccatc catgagccag catccgtccg tcctccactc tccagcctct 1850

 cccca 1855

<210> 2257
<211> 256
<212> PRT
<213> Homo sapien

<400> 2257
 Met Thr Ala Pro Gly Ala Ala Gly Arg Cys Pro Pro Thr Thr Trp
   1               5                  10                  15

 Leu Gly Ser Leu Leu Leu Leu Val Cys Leu Leu Ala Ser Arg Ser
                  20                  25                  30

 Ile Thr Glu Glu Val Ser Glu Tyr Cys Ser His Met Ile Gly Ser
                  35                  40                  45

 Gly His Leu Gln Ser Leu Gln Arg Leu Ile Asp Ser Gln Met Glu
                  50                  55                  60

 Thr Ser Cys Gln Ile Thr Phe Glu Phe Val Asp Gln Glu Gln Leu
                  65                  70                  75

 Lys Asp Pro Val Cys Tyr Leu Lys Lys Ala Phe Leu Leu Val Gln
                  80                  85                  90

 Asp Ile Met Glu Asp Thr Met Arg Phe Arg Asp Asn Thr Pro Asn
                  95                 100                 105

 Ala Ile Ala Ile Val Gln Leu Gln Glu Leu Ser Leu Arg Leu Lys
                 110                 115                 120

 Ser Cys Phe Thr Lys Asp Tyr Glu Glu His Asp Lys Ala Cys Val
                 125                 130                 135

 Arg Thr Phe Tyr Glu Thr Pro Leu Gln Leu Leu Glu Lys Val Lys
                 140                 145                 150

 Asn Val Phe Asn Glu Thr Lys Asn Leu Leu Asp Lys Asp Trp Asn
                 155                 160                 165

 Ile Phe Ser Lys Asn Cys Asn Asn Ser Phe Ala Glu Cys Ser Ser
                 170                 175                 180

 Gln Gly His Glu Arg Gln Ser Glu Gly Ser Ser Ser Pro Gln Leu
                 185                 190                 195

 Gln Glu Ser Val Phe His Leu Leu Val Pro Ser Val Ile Leu Val
                 200                 205                 210

 Leu Leu Ala Val Gly Gly Leu Leu Phe Tyr Arg Trp Arg Arg Arg
                 215                 220                 225

 Ser His Gln Glu Pro Gln Arg Ala Asp Ser Pro Leu Glu Gln Pro
                 230                 235                 240

 Glu Gly Ser Pro Leu Thr Gln Asp Asp Arg Gln Val Glu Leu Pro
                 245                 250                 255

 Val


<210> 2258
<211> 948
<212> DNA
<213> Homo sapien

<400> 2258
 ccattgacta actatggaag attataccaa aatagagaaa attggagaag 50

 gtacctatgg agttgtgtat aagggtagac acaaaactac aggtcaagtg 100

 gtagccatga aaaaaatcag actagaaagt gaagaggaag gggttcctag 150

 tactgcaatt cgggaaattt ctctattaaa ggaacttcgt catccaaata 200

 tagtcagtct tcaggatgtg cttatgcagg attccaggtt atatctcatc 250

 tttgagtttc tttccatgga tctgaagaaa tacttggatt ctatccctcc 300

 tggtcagtac atggattctt cacttgttaa ggtagtaaca ctctggtaca 350

 gatctccaga agtattgctg gggtcagctc gttactcaac tccagttgac 400

 atttggagta taggcaccat atttgctgaa ctagcaacta agaaaccact 450

 tttccatggg gattcagaaa ttgatcaact cttcaggatt ttcagagctt 500

 tgggcactcc caataatgaa gtgtggccag aagtggaatc tttacaggac 550

 tataagaata catttcccaa atggaaacca ggaagcctag catcccatgt 600

 caaaaacttg gatgaaaatg gcttggattt gctctcgaaa atgttaatct 650

 atgatccagc caaacgaatt tctggcaaaa tggcactgaa tcatccatat 700

 tttaatgatt tggacaatca gattaagaag atgtagcttt ctgacaaaaa 750

 gtttccatat gttatgtcaa cagatagttg tgtttttatt gttaactctt 800

 gtctattttt gtcttatata tatttctttg ttatcaaact tcagctgtac 850

 ttcgtcttct aatttcaaaa atataactta aaaatgtaaa tattctatat 900

 gaatttaaat ataattctgt aaatgtgaaa aaaaaaaaaa aaaaaaaa 948

<210> 2259
<211> 240
<212> PRT
<213> Homo sapien

<400> 2259
 Met Glu Asp Tyr Thr Lys Ile Glu Lys Ile Gly Glu Gly Thr Tyr
   1               5                  10                  15

 Gly Val Val Tyr Lys Gly Arg His Lys Thr Thr Gly Gln Val Val
                  20                  25                  30

 Ala Met Lys Lys Ile Arg Leu Glu Ser Glu Glu Glu Gly Val Pro
                  35                  40                  45

 Ser Thr Ala Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Arg His
                  50                  55                  60

 Pro Asn Ile Val Ser Leu Gln Asp Val Leu Met Gln Asp Ser Arg
                  65                  70                  75

 Leu Tyr Leu Ile Phe Glu Phe Leu Ser Met Asp Leu Lys Lys Tyr
                  80                  85                  90

 Leu Asp Ser Ile Pro Pro Gly Gln Tyr Met Asp Ser Ser Leu Val
                  95                 100                 105

 Lys Val Val Thr Leu Trp Tyr Arg Ser Pro Glu Val Leu Leu Gly
                 110                 115                 120

 Ser Ala Arg Tyr Ser Thr Pro Val Asp Ile Trp Ser Ile Gly Thr
                 125                 130                 135

 Ile Phe Ala Glu Leu Ala Thr Lys Lys Pro Leu Phe His Gly Asp
                 140                 145                 150

 Ser Glu Ile Asp Gln Leu Phe Arg Ile Phe Arg Ala Leu Gly Thr
                 155                 160                 165

 Pro Asn Asn Glu Val Trp Pro Glu Val Glu Ser Leu Gln Asp Tyr
                 170                 175                 180

 Lys Asn Thr Phe Pro Lys Trp Lys Pro Gly Ser Leu Ala Ser His
                 185                 190                 195

 Val Lys Asn Leu Asp Glu Asn Gly Leu Asp Leu Leu Ser Lys Met
                 200                 205                 210

 Leu Ile Tyr Asp Pro Ala Lys Arg Ile Ser Gly Lys Met Ala Leu
                 215                 220                 225

 Asn His Pro Tyr Phe Asn Asp Leu Asp Asn Gln Ile Lys Lys Met
                 230                 235                 240

<210> 2260
<211> 1062
<212> DNA
<213> Homo sapien

<400> 2260
 gcacgagcgg cacgagtaga cttctataga tccctttcta tagaacttaa 50

 tctacttaag tcagggagac cacccagaag gaaagagccc atactttcaa 100

 tcttaggcat aagttagctt gataagattt tcagaaaaat tcccttttaa 150

 ccacagaact cccccactgg aaaggattct gaaagaaatg aagtcagccc 200

 tcagaaatga agttgactgc ctgctggctt tctgttgact ggcccggagc 250

 tgtactgcaa gacccttgtg agcttcccta gtctaagagt aggatgtctg 300

 ctgaagtcat ccatcaggtt gaagaagcac ttgatacaga tgagaaggag 350

 atgctgctct ttttgtgccg ggatgttgct atagatgtgg ttccacctaa 400

 tgtcagggac cttctggata ttttacggga aagaggtaag ctgtctgtcg 450

 gggacttggc tgaactgctc tacagagtga ggcgatttga cctgctcaaa 500

 cgtatcttga agatggacag aaaagctgtg gagacccacc tgctcaggaa 550

 ccctcacctt gtttcggact atagagtgct gatggcagag attggtgagg 600

 atttggataa atctgatgtg tcctcattaa ttttcctcat gaaggattac 650

 atgggccgag gcaagataag caaggagaag agtttcttgg accttgtggt 700

 tgagttggag aaactaaatc tggttgcccc agatcaactg gatttattag 750

 aaaaatgcct aaagaacatc cacagaatag acctgaagac aaaaatccag 800

 aagtacaagc agtctgttca aggagcaggg acaagttaca ggaatgttct 850

 ccaagcagca atccaaaaga gtctcaagga tccttcaaat aacttcagga 900

 tgataacacc ctatgcccat tgtcctgatc tgaaaattct tggaaattgt 950

 tccatgtgat taacatggaa ctgcctctac ttaatcattc tgaatgatta 1000

 aatcgtttca ttttctaaat gtgtaaaaaa aaaaaaaaaa aaaaaaactc 1050

 gagggggggc cc 1062

<210> 2261
<211> 221
<212> PRT
<213> Homo sapien

<400> 2261
 Met Ser Ala Glu Val Ile His Gln Val Glu Glu Ala Leu Asp Thr
   1               5                  10                  15

 Asp Glu Lys Glu Met Leu Leu Phe Leu Cys Arg Asp Val Ala Ile
                  20                  25                  30

 Asp Val Val Pro Pro Asn Val Arg Asp Leu Leu Asp Ile Leu Arg
                  35                  40                  45

 Glu Arg Gly Lys Leu Ser Val Gly Asp Leu Ala Glu Leu Leu Tyr
                  50                  55                  60

 Arg Val Arg Arg Phe Asp Leu Leu Lys Arg Ile Leu Lys Met Asp
                  65                  70                  75

 Arg Lys Ala Val Glu Thr His Leu Leu Arg Asn Pro His Leu Val
                  80                  85                  90

 Ser Asp Tyr Arg Val Leu Met Ala Glu Ile Gly Glu Asp Leu Asp
                  95                 100                 105

 Lys Ser Asp Val Ser Ser Leu Ile Phe Leu Met Lys Asp Tyr Met
                 110                 115                 120

 Gly Arg Gly Lys Ile Ser Lys Glu Lys Ser Phe Leu Asp Leu Val
                 125                 130                 135

 Val Glu Leu Glu Lys Leu Asn Leu Val Ala Pro Asp Gln Leu Asp
                 140                 145                 150

 Leu Leu Glu Lys Cys Leu Lys Asn Ile His Arg Ile Asp Leu Lys
                 155                 160                 165

 Thr Lys Ile Gln Lys Tyr Lys Gln Ser Val Gln Gly Ala Gly Thr
                 170                 175                 180

 Ser Tyr Arg Asn Val Leu Gln Ala Ala Ile Gln Lys Ser Leu Lys
                 185                 190                 195

 Asp Pro Ser Asn Asn Phe Arg Met Ile Thr Pro Tyr Ala His Cys
                 200                 205                 210

 Pro Asp Leu Lys Ile Leu Gly Asn Cys Ser Met
                 215                 220

<210> 2262
<211> 2662
<212> DNA
<213> Homo sapien

<400> 2262
 gtctacacca gcggtgtcgc tgcccgaaag tgagagaagg ctgatattgc 50

 tagctggaat ccaggcctgg gtgctgcatg gtggcgcccc tccccgtgac 100

 caccgctgcg ttttctcggg ctttctctga ggagctgctc ttgtgctgtt 150

 tggcccctgc ctactcggaa tggaacaaag catcgaacaa acaactgaga 200

 tcctgttgtg cctatcacct gttgaagttg ccagtcttaa ggaaggaatc 250

 aatttctttc gcaataagag cactggcaaa gactacgtct tgtacaagaa 300

 taagagccga ctgagggcat gcaagaatat gtgcaagcac caaggaggcc 350

 tgttcataaa agatatcgag gatttagccg gaagttgttg aaatggatga 400

 aaacaacgga cttttgcttt tagaactgaa tcctcctaac ccttgggact 450

 tacagcccag atctcctgaa gagttggctt ttggagaagt acagataaca 500

 tatctcactc atgcctgcat ggacctcaag ttaggagaca agagaatggt 550

 gtttgaccct tggttaatcg gtcctgcttt tgcccgtgga tggtggttgc 600

 tccatgagcc tccatctgat tggctggaga ggctgtgcca ggcagacctc 650

 atttacatca gtcatctgca ctcagaccac ctgagttacc ccacactgaa 700

 aaagcttgct gggagaagac cagatattcc catttatgtt ggaaacacag 750

 aaaggcctgt attttggaat ctgaatcaga gcggtgtcca gttgactaat 800

 atcaatgtcg tgccatttgg aatatggcag caggtggaca aaaatcttcg 850

 attcatgatc ttgatggacg gtgttcatcc tgagatggac acttgcatta 900

 ttgtggagta caaaggtcat aaaatactca atatagtaga ctgcaccaga 950

 cccaatgggg gaaggctgcc tatgaaggtt gctctaatga tgagtgattt 1000

 tgctggagga gcatcaggct ttccaatgac tttcagtggt ggaaaattta 1050

 cggaggaatg gaaagcccaa ttcattaaaa cagaaaggaa gaagctcctg 1100

 aactacaagg ctcggctggt gaagaacctg caaccccgaa tttattgtcc 1150

 ctttgctggg tattttgtgg aatctcaccc atcagacaag tacatcaagg 1200

 aaacaaacac caaaaatgac ccaaatgaac tcaacaatct tatcaagaaa 1250

 aactctgatg tgataacatg gacccctcga ccgggagcca cccttgatct 1300

 gggaagaatg ctgaaggatc gaacagacag caagggcatc atagagcctc 1350

 cagaggggac aaaaatttac aaggattcct gggattttga accttatttg 1400

 gaaatcttga atgctgctct aggagatgaa atatttcttc actcatcctg 1450

 gataaaagaa tacttcactt gggctggatt taaagattac aaccttgtgg 1500

 tcaggatgat tgagacagat gaggacttca atccttttcc tggaggatat 1550

 gactatttgg ttgacttttt agatttatcc ttcccaaaag aaagaccaca 1600

 acgagaacat ccctatgagg aaatccatag ccgggtggat gtcatcagac 1650

 acgtggtgaa gaatggtcta ctctgggatg agttgtatat aggattccaa 1700

 acacggctcc agcgggatcc tgacatatac catcacctgt tttggaatca 1750

 ttttcaaata aaactccccc tcacaccacc caactggaag tcattcctga 1800

 tgtgctgtga gcagaatggg cctgcgattt tgcaagaatg caaaaccaca 1850

 tgaaaatttc aagaattcac tgatctgatg caaaataaaa atttatcatt 1900

 acatcttgaa cccaggaagc ttacagcaaa gagactatgc tttatgacgt 1950

 cagcaataga taattccacg ttgcctttgt gatttgtata tatagcttac 2000

 atttgtggat cactacatag ccagattcaa aaatatttta cttgttccat 2050

 ccacagttct ctacagaaag aaccaatgaa cccaatagga acaaattctc 2100

 tgtggaaaac aaagcatagc tgtagtagat acgaatccaa tcacagagga 2150

 aacaggaaga gaaaaacatc caagactaca gtgaaaactg gaaatggtct 2200

 gttttcgtga tattcgtatg attaagatgc aaattttttc ttaggaaaat 2250

 gtgattgtta actagcattc tgttttacat gttgacattt ctaacacaca 2300

 caccactgat ttgaacttca aaatttattt tctgattata tatgctaggt 2350

 ctgattctga agatacaaga attcaatggt ggaatttgtc tcctgaaatt 2400

 tctagattca taattagaag tgtttattac caacttctca cttagattaa 2450

 catcagtgat gtttgattat tctggttaac cgctcacatg cataacaata 2500

 atgctagaaa ttcaggaatt ataattttgt gatttatact gtgtggtaaa 2550

 ttattcagtt ctcactgcaa ataaatataa tgtatatcaa tgtaatgtag 2600

 gtcagaatgt ctatggtgag caaataaaag attattttaa aatatgaaaa 2650

 aaaaaaaaaa aa 2662

<210> 2263
<211> 486
<212> PRT
<213> Homo sapien

<400> 2263
 Met Asp Glu Asn Asn Gly Leu Leu Leu Leu Glu Leu Asn Pro Pro
   1               5                  10                  15

 Asn Pro Trp Asp Leu Gln Pro Arg Ser Pro Glu Glu Leu Ala Phe
                  20                  25                  30

 Gly Glu Val Gln Ile Thr Tyr Leu Thr His Ala Cys Met Asp Leu
                  35                  40                  45

 Lys Leu Gly Asp Lys Arg Met Val Phe Asp Pro Trp Leu Ile Gly
                  50                  55                  60

 Pro Ala Phe Ala Arg Gly Trp Trp Leu Leu His Glu Pro Pro Ser
                  65                  70                  75

 Asp Trp Leu Glu Arg Leu Cys Gln Ala Asp Leu Ile Tyr Ile Ser
                  80                  85                  90

 His Leu His Ser Asp His Leu Ser Tyr Pro Thr Leu Lys Lys Leu
                  95                 100                 105

 Ala Gly Arg Arg Pro Asp Ile Pro Ile Tyr Val Gly Asn Thr Glu
                 110                 115                 120

 Arg Pro Val Phe Trp Asn Leu Asn Gln Ser Gly Val Gln Leu Thr
                 125                 130                 135

 Asn Ile Asn Val Val Pro Phe Gly Ile Trp Gln Gln Val Asp Lys
                 140                 145                 150

 Asn Leu Arg Phe Met Ile Leu Met Asp Gly Val His Pro Glu Met
                 155                 160                 165

 Asp Thr Cys Ile Ile Val Glu Tyr Lys Gly His Lys Ile Leu Asn
                 170                 175                 180

 Ile Val Asp Cys Thr Arg Pro Asn Gly Gly Arg Leu Pro Met Lys
                 185                 190                 195

 Val Ala Leu Met Met Ser Asp Phe Ala Gly Gly Ala Ser Gly Phe
                 200                 205                 210

 Pro Met Thr Phe Ser Gly Gly Lys Phe Thr Glu Glu Trp Lys Ala
                 215                 220                 225

 Gln Phe Ile Lys Thr Glu Arg Lys Lys Leu Leu Asn Tyr Lys Ala
                 230                 235                 240

 Arg Leu Val Lys Asn Leu Gln Pro Arg Ile Tyr Cys Pro Phe Ala
                 245                 250                 255

 Gly Tyr Phe Val Glu Ser His Pro Ser Asp Lys Tyr Ile Lys Glu
                 260                 265                 270

 Thr Asn Thr Lys Asn Asp Pro Asn Glu Leu Asn Asn Leu Ile Lys
                 275                 280                 285

 Lys Asn Ser Asp Val Ile Thr Trp Thr Pro Arg Pro Gly Ala Thr
                 290                 295                 300

 Leu Asp Leu Gly Arg Met Leu Lys Asp Arg Thr Asp Ser Lys Gly
                 305                 310                 315

 Ile Ile Glu Pro Pro Glu Gly Thr Lys Ile Tyr Lys Asp Ser Trp
                 320                 325                 330

 Asp Phe Glu Pro Tyr Leu Glu Ile Leu Asn Ala Ala Leu Gly Asp
                 335                 340                 345

 Glu Ile Phe Leu His Ser Ser Trp Ile Lys Glu Tyr Phe Thr Trp
                 350                 355                 360

 Ala Gly Phe Lys Asp Tyr Asn Leu Val Val Arg Met Ile Glu Thr
                 365                 370                 375

 Asp Glu Asp Phe Asn Pro Phe Pro Gly Gly Tyr Asp Tyr Leu Val
                 380                 385                 390

 Asp Phe Leu Asp Leu Ser Phe Pro Lys Glu Arg Pro Gln Arg Glu
                 395                 400                 405

 His Pro Tyr Glu Glu Ile His Ser Arg Val Asp Val Ile Arg His
                 410                 415                 420

 Val Val Lys Asn Gly Leu Leu Trp Asp Glu Leu Tyr Ile Gly Phe
                 425                 430                 435

 Gln Thr Arg Leu Gln Arg Asp Pro Asp Ile Tyr His His Leu Phe
                 440                 445                 450

 Trp Asn His Phe Gln Ile Lys Leu Pro Leu Thr Pro Pro Asn Trp
                 455                 460                 465

 Lys Ser Phe Leu Met Cys Cys Glu Gln Asn Gly Pro Ala Ile Leu
                 470                 475                 480

 Gln Glu Cys Lys Thr Thr
                 485

<210> 2264
<211> 1294
<212> DNA
<213> Homo sapien

<400> 2264
 ccggcgcgac ccgcaggagc gtagagagcg cgggactaga gtgcagagct 50

 ccgggacgtg gatcggagcc ggcgcgatgg gcggagagca ggaggaggag 100

 cggttcgacg gcatgttgct ggccatggct cagcagcacg agggcggcgt 150

 gcaggagctt tgaacacctt cttcagcttc cttcgacgca aaacagactt 200

 tttcattgga ggagaagaag ggatggcaga gaagcttatc acacagactt 250

 tcagccacca caatcagctg gcacagaaga cccggcggga gaagagagcc 300

 cggcaggagg ccgagcggcg ggagaaggcg gagcgggcgg ccagactggc 350

 caaggaagcc aagtcagaga cctcagggcc ccagatcaag gagctaactg 400

 atgaagaggc agagaggctg cagctagaga ttgaccagaa aaaggatgca 450

 gagaatcatg aggcccagct caagaacggc agccttgact ccccagggaa 500

 gcaggatact gaggaagatg aggaggaaga tgagaaggac aaaggaaaac 550

 tgaagcccaa cctaggcaac ggggcagacc tgcccaatta ccgctggacc 600

 cagaccctst cggagctgga cctggcggtc cctttctgtg tgaacttccg 650

 gctgaaaggg aaggacatgg tggtggacat ccagcggcgg cacctccggg 700

 tggggctcaa ggggcagcca gcgatcattg atggggagct ctacaatgaa 750

 gtgaaggttg aggagagctc gtggctcatt gaggacggca aggtggtgac 800

 tgtgcatctg gagaagatca ataagatgga gtggtggagc cgcttggtgt 850

 ccaagtgacc actggagctc caaccgcggt ggcgcgctct agaacctagt 900

 ggatcccggc ctgcaggaat tcgcacgagg agactcgcag catggtggaa 950

 aagatgatgt atgaccagcg acagaagtcc atggggctgc caacttcaga 1000

 cgaacagaag aaacaggaga ttctgaagaa gttcatggat caacatccgg 1050

 agatggattt ttccaaggct aaattcaact agcccctgtt ttttcctccc 1100

 tgaactcttg gggctgagct gcaaccaccc aactttcttt cccactcttc 1150

 tctgggactt gtgggcctca gggcttgggg caggcatggg actggcccag 1200

 gcacacaggt cccggggcat caggagaaag gctgggtctt gggaccatgt 1250

 cctccaagtt ggcctactgt tacacattaa aacgatttgc ccag 1294

<210> 2265
<211> 211
<212> PRT
<213> Homo sapien

<400> 2265
 Met Ala Glu Lys Leu Ile Thr Gln Thr Phe Ser His His Asn Gln
   1               5                  10                  15

 Leu Ala Gln Lys Thr Arg Arg Glu Lys Arg Ala Arg Gln Glu Ala
                  20                  25                  30

 Glu Arg Arg Glu Lys Ala Glu Arg Ala Ala Arg Leu Ala Lys Glu
                  35                  40                  45

 Ala Lys Ser Glu Thr Ser Gly Pro Gln Ile Lys Glu Leu Thr Asp
                  50                  55                  60

 Glu Glu Ala Glu Arg Leu Gln Leu Glu Ile Asp Gln Lys Lys Asp
                  65                  70                  75

 Ala Glu Asn His Glu Ala Gln Leu Lys Asn Gly Ser Leu Asp Ser
                  80                  85                  90

 Pro Gly Lys Gln Asp Thr Glu Glu Asp Glu Glu Glu Asp Glu Lys
                  95                 100                 105

 Asp Lys Gly Lys Leu Lys Pro Asn Leu Gly Asn Gly Ala Asp Leu
                 110                 115                 120

 Pro Asn Tyr Arg Trp Thr Gln Thr Leu Ser Glu Leu Asp Leu Ala
                 125                 130                 135

 Val Pro Phe Cys Val Asn Phe Arg Leu Lys Gly Lys Asp Met Val
                 140                 145                 150

 Val Asp Ile Gln Arg Arg His Leu Arg Val Gly Leu Lys Gly Gln
                 155                 160                 165

 Pro Ala Ile Ile Asp Gly Glu Leu Tyr Asn Glu Val Lys Val Glu
                 170                 175                 180

 Glu Ser Ser Trp Leu Ile Glu Asp Gly Lys Val Val Thr Val His
                 185                 190                 195

 Leu Glu Lys Ile Asn Lys Met Glu Trp Trp Ser Arg Leu Val Ser
                 200                 205                 210

 Lys


<210> 2266
<211> 1060
<212> DNA
<213> Homo sapien

<400> 2266
 cgcgggccga ctggtgttta tccgtcactc gccgaggttc cttgggtcat 50

 ggtgccagcc tgactgagaa gaggacgctc ccgggagacg aatgaggaac 100

 cacctcctcc tactgttcaa gtacaggggc ctggtccgca aagggaagaa 150

 aagcaaaaga cgaaaatggc taaattcgtg atccgcccag ccactgccgc 200

 cgactgcagt gacatactgc ggctgatcaa ggagctggct aaatatgaat 250

 acatggaaga acaagtaatc ttaactgaaa aagatctgct agaagatggt 300

 tttggagagc acccctttta ccactgcctg gttgcagaag tgccgaaaga 350

 gcactggact ccggaaggac acagcattgt tggttttgcc atgtactatt 400

 ttacctatga cccgtggatt ggcaagttat tgtatcttga ggacttcttc 450

 gtgatgagtg attatagagg ctttggcata ggatcagaaa ttctgaagaa 500

 tctaagccag gttgcaatga ggtgtcgctg cagcagcatg cacttcttgg 550

 tagcagaatg gaatgaacca tccatcaact tctataaaag aagaggtgct 600

 tctgatctgt ccagtgaaga gggttggaga ctgttcaaga tcgacaagga 650

 gtacttgcta aaaatggcaa cagaggagtg aggagtgctg ctgtagatga 700

 caacctccat tctattttag aataaattcc caacttctct tgctttctat 750

 gctgtttgta gtgaaataat agaatgagca cccattccaa agctttatta 800

 ccagtggcgt tgttgcatgt ttgaaatgag gtctgtttaa agtggcaatc 850

 tcagatgcag tttggagagt cagatctttc tccttgaata tctttcgata 900

 aacaacaagg tggtgtgatc ttaatatatt tgaaaaaaac ttcattctcg 950

 tgagtcattt aaatgtgtac aatgtacaca ctggtactta gagtttctgt 1000

 ttgattcttt tttaataaac tactctttga tttaaaaaaa aaaaaaaaaa 1050

 aaaaaaaaaa 1060

<210> 2267
<211> 171
<212> PRT
<213> Homo sapien

<400> 2267
 Met Ala Lys Phe Val Ile Arg Pro Ala Thr Ala Ala Asp Cys Ser
   1               5                  10                  15

 Asp Ile Leu Arg Leu Ile Lys Glu Leu Ala Lys Tyr Glu Tyr Met
                  20                  25                  30

 Glu Glu Gln Val Ile Leu Thr Glu Lys Asp Leu Leu Glu Asp Gly
                  35                  40                  45

 Phe Gly Glu His Pro Phe Tyr His Cys Leu Val Ala Glu Val Pro
                  50                  55                  60

 Lys Glu His Trp Thr Pro Glu Gly His Ser Ile Val Gly Phe Ala
                  65                  70                  75

 Met Tyr Tyr Phe Thr Tyr Asp Pro Trp Ile Gly Lys Leu Leu Tyr
                  80                  85                  90

 Leu Glu Asp Phe Phe Val Met Ser Asp Tyr Arg Gly Phe Gly Ile
                  95                 100                 105

 Gly Ser Glu Ile Leu Lys Asn Leu Ser Gln Val Ala Met Arg Cys
                 110                 115                 120

 Arg Cys Ser Ser Met His Phe Leu Val Ala Glu Trp Asn Glu Pro
                 125                 130                 135

 Ser Ile Asn Phe Tyr Lys Arg Arg Gly Ala Ser Asp Leu Ser Ser
                 140                 145                 150

 Glu Glu Gly Trp Arg Leu Phe Lys Ile Asp Lys Glu Tyr Leu Leu
                 155                 160                 165

 Lys Met Ala Thr Glu Glu
                 170

<210> 2268
<211> 1364
<212> DNA
<213> Homo sapien

<400> 2268
 ctgtattgtg gttcctggaa cactttagag gcttgtgatt ctactgcttc 50

 ttattcacac tataatacat gtctcaccaa tagatgattc aagaacatca 100

 tttaaataca caatttttca ttctctattt ttgctaaatt tcttcatact 150

 caactttcag attctttaat ctccagctca gcttcaacaa ttcaacgctg 200

 ttctttctga aaaagtacac atcgtgcctt ctctacttcg ctcttggaac 250

 ataatttctc atggcagtgt ttaagaccac tctgtggagg ttaatttctg 300

 ggaccttagg gataatatgc ctttcgttga tggctacgtt gggaattttg 350

 ttgaaaaatt cttttactaa actgagtatt gagccagcat ttactccagg 400

 acccaacata gaactccaga aagactctga ctgctgttct tgccaagaaa 450

 aatgggttgg gtaccggtgc aactgttact tcatttccag tgaacagaaa 500

 acttggaacg aaagtcggca tctctgtgct tctcagaaat ccagcctgct 550

 tcagcttcaa aacacagatg aactggattt tatgagctcc agtcaacaat 600

 tttactggat tggactctct tacagtgagg agcacaccgc ctggttgtgg 650

 gagaatggct ctgcactctc ccagtatcta tttccatcat ttgaaacttt 700

 taatacaaag aactgcatag cgtataatcc aaatggaaat gctttagatg 750

 aatcctgtga agataaaaat cgttatatct gtaagcaaca gctcatttaa 800

 atgtttcttg gggcagagaa ggtggagagt aaagacccaa cattactaac 850

 aatgatacag ttgcatgtta tattattact aattgtctac ttctggagtc 900

 tataaaatgt ttttaaacag tgtcatatac aattgtcatg tatgtgaaac 950

 aatgtgtttt aaaattgatg aaattcgttc acctacattt gagaattata 1000

 aaattaacat aaagaatttt gtattttcat ttaatgtata taatgttaaa 1050

 ttcaatgtag ttttattaca catttatgta attttattta cattcttgct 1100

 aattctcagc agaaatttaa ataagattta attcacatca aataaaattt 1150

 agaaaataaa atttaactca cactgcccag gctggagcat agtggcaaga 1200

 tcatagctca ttgcaagctc aagtgatcct cctgactcag cctcccaagt 1250

 agctaggact gcaggcacca tgtcactatg cccgactaat ttttaatttt 1300

 taattttttg tcaagacaag gtcttgctat gttgcccagg ctggtcttga 1350

 actcctggcc tcaa 1364

<210> 2269
<211> 179
<212> PRT
<213> Homo sapien

<400> 2269
 Met Ala Val Phe Lys Thr Thr Leu Trp Arg Leu Ile Ser Gly Thr
   1               5                  10                  15

 Leu Gly Ile Ile Cys Leu Ser Leu Met Ala Thr Leu Gly Ile Leu
                  20                  25                  30

 Leu Lys Asn Ser Phe Thr Lys Leu Ser Ile Glu Pro Ala Phe Thr
                  35                  40                  45

 Pro Gly Pro Asn Ile Glu Leu Gln Lys Asp Ser Asp Cys Cys Ser
                  50                  55                  60

 Cys Gln Glu Lys Trp Val Gly Tyr Arg Cys Asn Cys Tyr Phe Ile
                  65                  70                  75

 Ser Ser Glu Gln Lys Thr Trp Asn Glu Ser Arg His Leu Cys Ala
                  80                  85                  90

 Ser Gln Lys Ser Ser Leu Leu Gln Leu Gln Asn Thr Asp Glu Leu
                  95                 100                 105

 Asp Phe Met Ser Ser Ser Gln Gln Phe Tyr Trp Ile Gly Leu Ser
                 110                 115                 120

 Tyr Ser Glu Glu His Thr Ala Trp Leu Trp Glu Asn Gly Ser Ala
                 125                 130                 135

 Leu Ser Gln Tyr Leu Phe Pro Ser Phe Glu Thr Phe Asn Thr Lys
                 140                 145                 150

 Asn Cys Ile Ala Tyr Asn Pro Asn Gly Asn Ala Leu Asp Glu Ser
                 155                 160                 165

 Cys Glu Asp Lys Asn Arg Tyr Ile Cys Lys Gln Gln Leu Ile
                 170                 175

<210> 2270
<211> 1080
<212> DNA
<213> Homo sapien

<400> 2270
 ccggggggca tgagggtccg agacttgttc ttctgtccct tccaagaccc 50

 ggcgacagga ggcatgaggg gcccccggcc gaaatgacag tgctggcgcc 100

 agcctggagc ccaacaacct atctcctcct gctgctgctg ctgagctcgg 150

 gactcagtgg gacccaggac tgctccttcc aacacagccc catctcctcc 200

 gacttcgctg tcaaaatccg tgagctgtct gactacctgc ttcaagatta 250

 cccagtcacc gtggcctcca acctgcagga cgaggagctc tgcgggggcc 300

 tctggcggct ggtcctggca cagcgctgga tggagcggct caagactgtc 350

 gctgggtcca agatgcaagg cttgctggag cgcgtgaaca cggagataca 400

 ctttgtcacc aaatgtgcct ttcagccccc ccccagctgt cttcgcttcg 450

 tccagaccaa catctcccgc ctcctgcagg agacctccga gcagctggtg 500

 gcgctgaagc cctggatcac tcgccagaac ttctcccggt gcctggagct 550

 gcagtgtcag cccgactcct caaccctgcc acccccatgg agtccccggc 600

 ccctggaggc cacagccccg acagccccgc agccccctct gctcctccta 650

 ctgctgctgc ccgtgggcct cctgctgctg gccgctgcct ggtgcctgca 700

 ctggcagagg acgcggcgga ggacaccccg ccctggggag caggtgcccc 750

 ccgtccccag tccccaggac ctgctgcttg tggagcactg acctggccaa 800

 ggcctcatcc tgcggagcct taaacaacgc agtgagacag acatctatca 850

 tcccatttta caggggagga tactgaggca cacagagggg agtcaccagc 900

 cagaggatgt atagcctgga cacagaggaa gttggctaga ggccggtccc 950

 ttccttgggc ccctctcatt ccctccccag aatggaggca acgccagaat 1000

 ccagcaccgg ccccatttac ccaactctga acaaagccct tgcccccatg 1050

 aaattgttta taaatcatcc ttttctccca 1080

<210> 2271
<211> 235
<212> PRT
<213> Homo sapien

<400> 2271
 Met Thr Val Leu Ala Pro Ala Trp Ser Pro Thr Thr Tyr Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Leu Ser Ser Gly Leu Ser Gly Thr Gln Asp Cys
                  20                  25                  30

 Ser Phe Gln His Ser Pro Ile Ser Ser Asp Phe Ala Val Lys Ile
                  35                  40                  45

 Arg Glu Leu Ser Asp Tyr Leu Leu Gln Asp Tyr Pro Val Thr Val
                  50                  55                  60

 Ala Ser Asn Leu Gln Asp Glu Glu Leu Cys Gly Gly Leu Trp Arg
                  65                  70                  75

 Leu Val Leu Ala Gln Arg Trp Met Glu Arg Leu Lys Thr Val Ala
                  80                  85                  90

 Gly Ser Lys Met Gln Gly Leu Leu Glu Arg Val Asn Thr Glu Ile
                  95                 100                 105

 His Phe Val Thr Lys Cys Ala Phe Gln Pro Pro Pro Ser Cys Leu
                 110                 115                 120

 Arg Phe Val Gln Thr Asn Ile Ser Arg Leu Leu Gln Glu Thr Ser
                 125                 130                 135

 Glu Gln Leu Val Ala Leu Lys Pro Trp Ile Thr Arg Gln Asn Phe
                 140                 145                 150

 Ser Arg Cys Leu Glu Leu Gln Cys Gln Pro Asp Ser Ser Thr Leu
                 155                 160                 165

 Pro Pro Pro Trp Ser Pro Arg Pro Leu Glu Ala Thr Ala Pro Thr
                 170                 175                 180

 Ala Pro Gln Pro Pro Leu Leu Leu Leu Leu Leu Leu Pro Val Gly
                 185                 190                 195

 Leu Leu Leu Leu Ala Ala Ala Trp Cys Leu His Trp Gln Arg Thr
                 200                 205                 210

 Arg Arg Arg Thr Pro Arg Pro Gly Glu Gln Val Pro Pro Val Pro
                 215                 220                 225

 Ser Pro Gln Asp Leu Leu Leu Val Glu His
                 230                 235

<210> 2272
<211> 643
<212> DNA
<213> Homo sapien

<400> 2272
 gggagaagtt aaagccagag gaggggcagg aatgtctgag gtggcaacac 50

 ttctcttcag ccagacagca ctggccagtt tggagtctgt ccatcctgca 100

 ggccacaagc tctggatgag gaacttgagg caagtcacca gcccctgatc 150

 atttcgccta aaagagcaag gactagagtt cctgacctcc aggccagtcc 200

 ctgatccctg acctaatgtt atcgcggaat gatgatatat gtatctacgg 250

 gggcctgggg ctgggcgggc tcctgcttct ggcagtggtc cttctgtccg 300

 cctgcctgtg ttggctgcat cgaagagtaa agaggctgga gaggagctgg 350

 acccagggct cctcagagca ggaactccac tatgcatctc tgcagaggct 400

 gccagtgccc agcagtgagg gacctgacct caggggcaga gacaagagag 450

 gcaccaagga ggatccaaga gctgactatg cctgcattgc tgagaacaaa 500

 cccacctgag caccccagac accttcctca acccaggcgg gtggacaggg 550

 tccccctgtg gtccagccag taaaaaccat ggtcccccca cttctgtgtc 600

 tcagtcctct cagtccatct cgagcctccg ttcaaattga tca 643

<210> 2273
<211> 97
<212> PRT
<213> Homo sapien

<400> 2273
 Met Leu Ser Arg Asn Asp Asp Ile Cys Ile Tyr Gly Gly Leu Gly
   1               5                  10                  15

 Leu Gly Gly Leu Leu Leu Leu Ala Val Val Leu Leu Ser Ala Cys
                  20                  25                  30

 Leu Cys Trp Leu His Arg Arg Val Lys Arg Leu Glu Arg Ser Trp
                  35                  40                  45

 Thr Gln Gly Ser Ser Glu Gln Glu Leu His Tyr Ala Ser Leu Gln
                  50                  55                  60

 Arg Leu Pro Val Pro Ser Ser Glu Gly Pro Asp Leu Arg Gly Arg
                  65                  70                  75

 Asp Lys Arg Gly Thr Lys Glu Asp Pro Arg Ala Asp Tyr Ala Cys
                  80                  85                  90

 Ile Ala Glu Asn Lys Pro Thr
                  95

<210> 2274
<211> 2226
<212> DNA
<213> Homo sapien

<400> 2274
 ctcgacccac gcgtccgcgc gccccaggag ccaaagccgg gctccaagtc 50

 ggcgccccac gtcgaggctc cgccgcagcc tccggagttg gccgcagaca 100

 agaaggggag ggagcgggag agggaggaga gctccgaagc gagagggccg 150

 agcgccatgc gccgcgccag cagagactac accaagtacc tgcgtggctc 200

 ggaggagatg ggcggcggcc ccggagcccc gcacgagggc cccctgcacg 250

 ccccgccgcc gcctgcgccg caccagcccc ccgccgcctc ccgctccatg 300

 ttcgtggccc tcctggggct ggggctgggc caggttgtct gcagcgtcgc 350

 cctgttcttc tatttcagag cgcagatgga tcctaataga atatcagaag 400

 atggcactca ctgcatttat agaattttga gactccatga aaatgcagat 450

 tttcaagaca caactctgga gagtcaagat acaaaattaa tacctgattc 500

 atgtaggaga attaaacagg cctttcaagg agctgtgcaa aaggaattac 550

 aacatatcgt tggatcacag cacatcagag cagagaaagc gatggtggat 600

 ggctcatggt tagatctggc caagaggagc aagcttgaag ctcagccttt 650

 tgctcatctc actattaatg ccaccgacat cccatctggt tcccataaag 700

 tgagtctgtc ctcttggtac catgatcggg gttgggccaa gatctccaac 750

 atgactttta gcaatggaaa actaatagtt aatcaggatg gcttttatta 800

 cctgtatgcc aacatttgct ttcgacatca tgaaacttca ggagacctag 850

 ctacagagta tcttcaacta atggtgtacg tcactaaaac cagcatcaaa 900

 atcccaagtt ctcataccct gatgaaagga ggaagcacca agtattggtc 950

 agggaattct gaattccatt tttattccat aaacgttggt ggatttttta 1000

 agttacggtc tggagaggaa atcagcatcg aggtctccaa cccctcctta 1050

 ctggatccgg atcaggatgc aacatacttt ggggctttta aagttcgaga 1100

 tatagattga gccccagttt ttggagtgtt atgtatttcc tggatgtttg 1150

 gaaacatttt ttaaaacaag ccaagaaaga tgtatatagg tgtgtgagac 1200

 tactaagagg catggcccca acggtacacg actcagtatc catgctcttg 1250

 accttgtaga gaacacgcgt atttacagcc agtgggagat gttagactca 1300

 tggtgtgtta cacaatggtt tttaaatttt gtaatgaatt cctagaatta 1350

 aaccagattg gagcaattac gggttgacct tatgagaaac tgcatgtggg 1400

 ctatgggagg ggttggtccc tggtcatgtg ccccttcgca gctgaagtgg 1450

 agagggtgtc atctagcgca attgaaggat catctgaagg ggcaaattct 1500

 tttgaattgt tacatcatgc tggaacctgc aaaaaatact ttttctaatg 1550

 aggagagaaa atatatgtat ttttatataa tatctaaagt tatatttcag 1600

 atgtaatgtt ttctttgcaa agtattgtaa attatatttg tgctatagta 1650

 tttgattcaa aatatttaaa aatgtcttgc tgttgacata tttaatgttt 1700

 taaatgtaca gacatattta actggtgcac tttgtaaatt ccctggggaa 1750

 aacttgcagc taaggagggg aaaaaaatgt tgtttcctaa tatcaaatgc 1800

 agtatatttc ttcgttcttt ttaagttaat agattttttc agacttgtca 1850

 agcctgtgca aaaaaattaa aatggatgcc ttgaataata agcaggatgt 1900

 tggccaccag gtgcctttca aatttagaaa ctaattgact ttagaaagct 1950

 gacattgcca aaaaggatac ataatgggcc actgaaatct gtcaagagta 2000

 gttatataat tgttgaacag gtgtttttcc acaagtgccg caaattgtac 2050

 cttttttttt ttttcaaaat agaaaagtta ttagtggttt atcagcaaaa 2100

 aagtccaatt ttaatttagt aaatgttatc ttatactgta caataaaaac 2150

 attgcctttg aatgttaatt ttttggtaca aaaataaatt tatatgaaaa 2200

 cctgaaaaaa aaaacaaaaa aaaaaa 2226

<210> 2275
<211> 317
<212> PRT
<213> Homo sapien

<400> 2275
 Met Arg Arg Ala Ser Arg Asp Tyr Thr Lys Tyr Leu Arg Gly Ser
   1               5                  10                  15

 Glu Glu Met Gly Gly Gly Pro Gly Ala Pro His Glu Gly Pro Leu
                  20                  25                  30

 His Ala Pro Pro Pro Pro Ala Pro His Gln Pro Pro Ala Ala Ser
                  35                  40                  45

 Arg Ser Met Phe Val Ala Leu Leu Gly Leu Gly Leu Gly Gln Val
                  50                  55                  60

 Val Cys Ser Val Ala Leu Phe Phe Tyr Phe Arg Ala Gln Met Asp
                  65                  70                  75

 Pro Asn Arg Ile Ser Glu Asp Gly Thr His Cys Ile Tyr Arg Ile
                  80                  85                  90

 Leu Arg Leu His Glu Asn Ala Asp Phe Gln Asp Thr Thr Leu Glu
                  95                 100                 105

 Ser Gln Asp Thr Lys Leu Ile Pro Asp Ser Cys Arg Arg Ile Lys
                 110                 115                 120

 Gln Ala Phe Gln Gly Ala Val Gln Lys Glu Leu Gln His Ile Val
                 125                 130                 135

 Gly Ser Gln His Ile Arg Ala Glu Lys Ala Met Val Asp Gly Ser
                 140                 145                 150

 Trp Leu Asp Leu Ala Lys Arg Ser Lys Leu Glu Ala Gln Pro Phe
                 155                 160                 165

 Ala His Leu Thr Ile Asn Ala Thr Asp Ile Pro Ser Gly Ser His
                 170                 175                 180

 Lys Val Ser Leu Ser Ser Trp Tyr His Asp Arg Gly Trp Ala Lys
                 185                 190                 195

 Ile Ser Asn Met Thr Phe Ser Asn Gly Lys Leu Ile Val Asn Gln
                 200                 205                 210

 Asp Gly Phe Tyr Tyr Leu Tyr Ala Asn Ile Cys Phe Arg His His
                 215                 220                 225

 Glu Thr Ser Gly Asp Leu Ala Thr Glu Tyr Leu Gln Leu Met Val
                 230                 235                 240

 Tyr Val Thr Lys Thr Ser Ile Lys Ile Pro Ser Ser His Thr Leu
                 245                 250                 255

 Met Lys Gly Gly Ser Thr Lys Tyr Trp Ser Gly Asn Ser Glu Phe
                 260                 265                 270

 His Phe Tyr Ser Ile Asn Val Gly Gly Phe Phe Lys Leu Arg Ser
                 275                 280                 285

 Gly Glu Glu Ile Ser Ile Glu Val Ser Asn Pro Ser Leu Leu Asp
                 290                 295                 300

 Pro Asp Gln Asp Ala Thr Tyr Phe Gly Ala Phe Lys Val Arg Asp
                 305                 310                 315

 Ile Asp


<210> 2276
<211> 1715
<212> DNA
<213> Homo sapien

<400> 2276
 agttctgtcc ttgcattggt gcgcctcagg ccaggctgca ctgctgggac 50

 ctgggccatg tctccccacc ccaccgccct cctgggccta gtgctctgcc 100

 tggcccagac catccacacg caggaggaag atctgcccag accctccatc 150

 tcggctgagc caggcaccgt gatccccctg gggagccatg tgactttcgt 200

 gtgccggggc ccggttgggg ttcaaacatt ccgcctggag agggagagta 250

 gatccacata caatgatact gaagatgtgt ctcaagctag tccatctgag 300

 tcagaggcca gattccgcat tgactcagta agtgaaggaa atgccgggcc 350

 ttatcgctgc atctattata agccccctaa atggtctgag cagagtgact 400

 acctggagct gctggtgaaa gaaacctctg gaggcccgga ctccccggac 450

 acagagcccg gctcctcagc tggacccacg cagaggccgt cggacaacag 500

 tcacaatgag catgcacctg cttcccaagg cctgaaagct gagcatctgt 550

 atattctcat cggggtctca gtggtcttcc tcttctgtct cctcctcctg 600

 gtcctcttct gcctccatcg ccagaatcag ataaagcagg ggccccccag 650

 aagcaaggac gaggagcaga agccacagca gaggcctgac ctggctgttg 700

 atgttctaga gaggacagca gacaaggcca cagtcaatgg acttcctgag 750

 aaggacagag agacggacac ctcggccctg gctgcaggga gttcccagga 800

 ggtgacgtat gctcagctgg accactgggc cctcacacag aggacagccc 850

 gggctgtgtc cccacagtcc acaaagccca tggccgagtc catcacgtat 900

 gcagccgttg ccagacactg accccatacc cacctggcct ctgcacctga 950

 gggtagaaag tcactctagg aaaagcctga agcagccatt tggaaggctt 1000

 cctgttggat tcctcttcat ctagaaagcc agccaggcag ctgtcctgga 1050

 gacaagagct ggagactgga ggtttctaac cagcatccag aaggttcgtt 1100

 agccaggtgg tcccttctac aatcgagcag ctccttggac agactgtttc 1150

 tcagttattt ccagagaccc agctacagtt ccctggctgt ttctagagac 1200

 ccagctttat tcacctgact gtttccagag acccagctaa agtcacctgc 1250

 ctgttctaaa ggcccagcta cagccaatca gccgatttcc tgagcagtga 1300

 tgccacctcc aagcttgtcc taggtgtctg ctgtgaacct ccagtgaccc 1350

 cagagacttt gctgtaatta tctgccctgc tgaccctaaa gaccttccta 1400

 gaagtcaaga gctagccttg agactgtgct atacacacac agctgagagc 1450

 caagcccagt tctctgggtt gtgctttact ccacgcatca ataaataatt 1500

 ttgaaggcct cacatctggc agccccaggc ctggtcctgg gtgcataggt 1550

 ctctcggacc cactctctgc cttcacagtt gttcaaagct gagtgaggga 1600

 aacaggactt acgaaaacgt gtcagcgttt tctttttaaa atttaattga 1650

 tcaggattgt acgtaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aaaaaaaaaa aaaaa 1715

<210> 2277
<211> 287
<212> PRT
<213> Homo sapien

<400> 2277
 Met Ser Pro His Pro Thr Ala Leu Leu Gly Leu Val Leu Cys Leu
   1               5                  10                  15

 Ala Gln Thr Ile His Thr Gln Glu Glu Asp Leu Pro Arg Pro Ser
                  20                  25                  30

 Ile Ser Ala Glu Pro Gly Thr Val Ile Pro Leu Gly Ser His Val
                  35                  40                  45

 Thr Phe Val Cys Arg Gly Pro Val Gly Val Gln Thr Phe Arg Leu
                  50                  55                  60

 Glu Arg Glu Ser Arg Ser Thr Tyr Asn Asp Thr Glu Asp Val Ser
                  65                  70                  75

 Gln Ala Ser Pro Ser Glu Ser Glu Ala Arg Phe Arg Ile Asp Ser
                  80                  85                  90

 Val Ser Glu Gly Asn Ala Gly Pro Tyr Arg Cys Ile Tyr Tyr Lys
                  95                 100                 105

 Pro Pro Lys Trp Ser Glu Gln Ser Asp Tyr Leu Glu Leu Leu Val
                 110                 115                 120

 Lys Glu Thr Ser Gly Gly Pro Asp Ser Pro Asp Thr Glu Pro Gly
                 125                 130                 135

 Ser Ser Ala Gly Pro Thr Gln Arg Pro Ser Asp Asn Ser His Asn
                 140                 145                 150

 Glu His Ala Pro Ala Ser Gln Gly Leu Lys Ala Glu His Leu Tyr
                 155                 160                 165

 Ile Leu Ile Gly Val Ser Val Val Phe Leu Phe Cys Leu Leu Leu
                 170                 175                 180

 Leu Val Leu Phe Cys Leu His Arg Gln Asn Gln Ile Lys Gln Gly
                 185                 190                 195

 Pro Pro Arg Ser Lys Asp Glu Glu Gln Lys Pro Gln Gln Arg Pro
                 200                 205                 210

 Asp Leu Ala Val Asp Val Leu Glu Arg Thr Ala Asp Lys Ala Thr
                 215                 220                 225

 Val Asn Gly Leu Pro Glu Lys Asp Arg Glu Thr Asp Thr Ser Ala
                 230                 235                 240

 Leu Ala Ala Gly Ser Ser Gln Glu Val Thr Tyr Ala Gln Leu Asp
                 245                 250                 255

 His Trp Ala Leu Thr Gln Arg Thr Ala Arg Ala Val Ser Pro Gln
                 260                 265                 270

 Ser Thr Lys Pro Met Ala Glu Ser Ile Thr Tyr Ala Ala Val Ala
                 275                 280                 285

 Arg His


<210> 2278
<211> 9009
<212> DNA
<213> Homo sapien

<400> 2278
 cctaaagaaa agtattaagt aaatagcagt acagatggca aatggattgc 50

 acaatatatc ctctggatcc atagtgaccc tgcagagata aacctgtgat 100

 ggtcaaacaa tgtgaaaact gctgtcagag acatgggcag ggtgctcttg 150

 tttacagaga agaggtgcaa aaatcaactt gatggtagtg ggaagatcag 200

 gaaatgcttc ctgaaattga gtattaagaa ctaatagaca ttaggtggtt 250

 gcagaataag ttttgtttag gaaggacaag cagttgggta tgactggctt 300

 ctaggttgtg tgttgtggag tgactgggga taaaagcagg agcaagatca 350

 caaaaggtct tctatgctta tattagggaa gttggacttt attctcaagc 400

 tgaagggaag ctgttgcatg gttttaagca gtaaagtgat atgatcagag 450

 ttttagagga tgccaagatt gaaggcaagt ctgaccagtt aggagactgc 500

 ttgttaaatt agttcagagg agaaacagtg aaggcagtgg cactgggcat 550

 gaagaagtat atgtgtgcta attttagatt tcttagggaa gcagaaatga 600

 caagagttag tggtccattg gacagaaata ttgaaggaga ctggggagtc 650

 taggttgact cccagggttt aggtttgggc agtaaaatga catgtagaac 700

 aattaactga taaacagcat acagaaagag gaaagaactt catttcatat 750

 gtttgttttt gaggaaaaga tgtttgtttt tgaacttcct gattcagagg 800

 ggcttgtggg acatcttggt taagatcctg tagtagttct agtagggtct 850

 agaagtcaag agatacaacc ccgcctggaa ggatttggga gtcttcagca 900

 tttggaattt tggaagccat tgtttactgc agtgcatatg agataattta 950

 aactggtaca tagataaaca cttgaaaaaa ttttaataga taggaattta 1000

 atgtgtatga gaaacataac ttgcacatct aacctttgat aatcatggac 1050

 attatcactt aggccaagtg agctcaataa aagggaaata ttaactaaaa 1100

 atatatgtga tacatggaaa tggcaaaaat cacggtgaag ctatgcaaac 1150

 gatgcaagtt cagaaagtgc tgtgttaagt catgggtgtg gtggataaat 1200

 tcacccaagg agagagtaag agtgagaaga aaagagagtt gacattgggt 1250

 ggcggggaat ggagaagaag aacccatgaa ggaaactgag gaagagcagc 1300

 cagacgaata ggaggaaaac caggagaaga tggtctttgg agtccaaatg 1350

 aagagttctg aggaggaagt ggtccacagc gtcaaacttg tgcaccatgg 1400

 acaattttgc tgagggagat ttcactgtgg cggattatgc cttgttagaa 1450

 gattgccctc acgtggatga ttgtgtcttt gctgctgaat ttatgagcaa 1500

 tgattatgtt cgtgtgactc agctttactg tgatggggtg ggtgtgcaat 1550

 ataaagatta tatccaaagt gagaggaatt tggaatttga catctgcagt 1600

 atatggtgta gtaaaccaat ttctgtcctg caagattatt gcgatgccat 1650

 taaaataaac atcttctggc cacttctgtt tcaacatcaa aacagttccg 1700

 taatatcacg attgcatccc tgtgtggacg ccaacaattc acgtgcttct 1750

 gagataaatt tgaagaaact acaacatctt gagttgatgg aagatattgt 1800

 ggatttggca aagaaagttg ctaatgattc attccttatt ggaggcttat 1850

 tgagaattgg ttgtaaaata gaaaataaaa tcttggcaat ggaagaagct 1900

 ctgaattgga taaaatatgc aggcgatgta acaattctaa ctaaattagg 1950

 atcaattgac aattgttggc ctatgttaag tattttcttt actgaataca 2000

 agtaccacat aactaaaatt gtaatggaag actgcaattt gcttgaagaa 2050

 cttaaaactc aaagttgtat ggattgtata gaggaaggag aactaatgaa 2100

 aatgaaagga aatgaagagt tttccaaaga aagatttgat atagctatta 2150

 tctattacac cagagccatt gaatatagac ctgaaaacta ccttctttat 2200

 ggtaaccgag ctctttgttt tcttcgtact ggacagttta gaaatgcact 2250

 cggtgatgga aagagagcca ctattctgaa gaacacttgg ccaaagggtc 2300

 attatcgtta ttgtgatgct ctttctatgc tgggggaata tgactgggcc 2350

 ctgcaagcaa acataaaagc tcaaaaactc tgtaaaaatg accctgaggg 2400

 aatcaaggat ctaattcagc agcatgtaaa gttacaaaaa caaatagaag 2450

 acctacaagg tcgaacagca aataaggatc caattaaagc cttttatgaa 2500

 aacagggcct acacacctag gagtttatca gcacctatat ttactacttc 2550

 acttaacttt gtggagaagg aaagagattt cagaaaaatt aatcacgaaa 2600

 tggccaacgg tggtaatcag aatctaaagg tggcggatga ggcgttgaag 2650

 gtagatgatt gtgactgtca tcctgaattt tcaccaccat caagtcagcc 2700

 tccaaaacat aaaggaaaac aaaaatctcg aaacaatgaa tcagaaaagt 2750

 tcagttctag ttcaccattg actttaccag cagatttgaa gaacatcttg 2800

 gagaaacagt tttctaaatc ttccagagct gcacaccagg attttgctaa 2850

 tataatgaaa atgctgagaa gcttaattca agatggctat atggccttat 2900

 tggagcagcg ttgccgcagc gctgcacagg cctttacaga gttgctgaac 2950

 ggtttagatc ctcaaaaaat aaagcaattg aacctggcca tgattaacta 3000

 tgttttggtc gtctatggac ttgccatttc tctccttgga ataggacagc 3050

 ctgaggaatt atctgaagcc gaaaaccagt ttaagaggat tattgaacac 3100

 taccccagtg agggccttga ttgcttggcc tactgtggaa ttggaaaagt 3150

 gtatttgaaa aaaaacagat ttctagaagc tctcaatcac tttgagaaag 3200

 caagaacctt gatttatcgt cttcctggag tgttaacttg gcccacgagt 3250

 aatgtgatta ttgaagagtc tcagccacaa aaaataaaga tgctgttaga 3300

 gaaatttgtt gaagaatgca agttccctcc agtgccagat gccatttgtt 3350

 gctatcagaa gtgccatgga tattctaaga tccagatata cataactgat 3400

 ccagacttta agggttttat acgcatcagc tgttgccagt actgtaaaat 3450

 agaatttcac atgaattgct ggaagaagtt aaaaactaca acctttaatg 3500

 ataaaattga caaggatttt ctacaaggaa tatgtcttac ccctgactgt 3550

 gaaggtgtca tttctaagat tatcatcttc agcagtggtg gtgaagttaa 3600

 atgtgaattt gaacacaagg tcataaaaga aaaggttcct ccaagaccta 3650

 ttctgaaaca gaaatgttct agcctagaga aactaagact gaaagaagac 3700

 aaaaaattga agagaaagat ccaaaaaaaa gaagcaaaaa agttagcaca 3750

 agaaagaatg gaggaggact taagagaaag taatccaccc aaaaatgaag 3800

 agcagaaaga aactgtagac aatgttcagc gttgtcagtt ccttgatgac 3850

 agaattctac agtgtataaa gcagtatgct gacaagatta aatccggcat 3900

 acagaataca gccatgcttc tcaaagaatt gctttcttgg aaagttttga 3950

 gcacagaaga ctatacaacc tgtttttcta gcagaaattt tctaaatgaa 4000

 gcagtggact atgttattcg ccacttgatt caagaaaata acagagtaaa 4050

 gacaagaata tttctgcatg ttttgagtga gcttaaagaa gtggagccca 4100

 aattagccgc ctggatccaa aaacttaata gctttggctt agatgccaca 4150

 ggaactttct tttctcgtta tggagcatct cttaaactgc ttgattttag 4200

 tatcatgact ttcctctgga atgagaaata tggtcacaaa ctagactcta 4250

 tagaaggaaa gcaacttgat tatttctctg agccagcatc attgaaggaa 4300

 gcccgttgtt taatatggct gctagaagaa cacagagaca agttcccagc 4350

 attgcatagt gctttagatg aattctttga tataatggac agccgctgta 4400

 ctgtgttaag gaaacaagat agtggtgaag caccgtttag ttcaaccaag 4450

 gtgaaaaaca aaagcaagaa aaagaagcca aaggattcaa agcctatgtt 4500

 agttgggtct ggaacaactt cagtaacttc aaataatgag atcatcactt 4550

 caagtgaaga ccatagcaat cgaaattcag attctgcagg cccatttgca 4600

 gtgcctgacc atcttcggca agatgtagaa gaattcgaag ctctctatga 4650

 ccaacacagt aacgaatatg ttgtccgcaa taagaagcta tgggacatga 4700

 acccaaaaca aaaatgttca actctatatg attacttctc tcagtttttg 4750

 gaggaacatg gtcccttgga catgagtaac aagatgttct ctgcagaata 4800

 tgagtttttc ccagaagaaa ctcgacagat actagaaaaa gcaggaggtt 4850

 taaaaccttt tctcttggga tgccctcgtt ttgttgtgat tgacaactgt 4900

 attgcactga agaaggttgc atcacggctc aagaaaaaaa ggaagaagaa 4950

 aaacattaaa acaaaagtag aagaaatttc aaaagcaggg gagtatgtac 5000

 gagttaaact acaactgaat ccagctgcta gggaatttaa accagatgta 5050

 aagtctaaac cagtgtcaga ttcatcttca gcaccagctt ttgaaaatgt 5100

 gaaacccaaa cctgtgtctg caaattctcc caagccagct tgtgaagatg 5150

 tgaaggccaa accagtatcc gacaattctt ctagacaagt ttctgaggat 5200

 gggcaaccca aaggggtctc ttctaattct cctaaaccag gctctgagga 5250

 tgcaaattac aagcgagtct cctgtaattc ccccaaaccg gttcttgagg 5300

 atgtgaaacc aacttattgg gctcaatccc atttggtcac aggatactgt 5350

 acgtatcttc ctttccagag atttgatatc acccagacac cgccagcata 5400

 cataaacgtg ttaccaggtt tgccccagta caccagcata tatacaccct 5450

 tggccagcct ttctcctgaa tatcagctac caagatcagt accagtggtg 5500

 ccgtcttttg tagccaatga cagagcagat aaaaatgctg ctgcctattt 5550

 tgagggtcat catttgaatg ctgagaatgt tgctggtcac cagattgcct 5600

 ctgaaacaca gatccttgag ggctctttgg gaatatctgt aaagtcacac 5650

 tgcagcacag gtgatgctca tacagtcctg agtgagtcta acagaaatga 5700

 tgagcactgt ggaaattcta acaacaaatg tgaagtaatt ccagaaagca 5750

 ccagtgcagt aacaaacatt ccacacgtgc agatggttgc catacaggta 5800

 tcttggaaca taatacacca agaagtcaat actgagccat ataatccttt 5850

 tgaggaacga caaggggaaa tttcacggat tgaaaaggag caccaagtat 5900

 tacaagacca acttcaagaa gtgtatgaaa attatgagca gataaaactt 5950

 aagggcttag aagagaccag ggacctggaa gagaagttga aaaggcactt 6000

 agaagaaaac aagatctcaa agacggaatt agattggttc cttcaagatt 6050

 tggaaagaga aattaaaaaa tggcaacagg aaaaaaaaga aatccaagaa 6100

 agactaaaat cactgaagaa gaaaattaaa aaggtttcaa atgccagtga 6150

 aatgtatacc cagaaaaatg atggaaagga aaaggaacat gaattacatc 6200

 tggatcagtc ccttgaaatc agcaacacac ttacaaatga gaaaatgaaa 6250

 atagaagagt atataaagaa agggaaagag gattatgaag agagtcatca 6300

 gagagctgtg gctgcagagg tatccgtact tgaaaactgg aaggagagtg 6350

 aagtgtataa gctacagatc atggagtcac aagcagaagc ctttctgaag 6400

 aagctggggc tgattagccg tgatcctgca gcatatcctg acatggagtc 6450

 tgatatacgt tcatgggaat tgtttctttc taatgttaca aaagaaattg 6500

 agaaagcaaa gtctcagttt gaagaacaaa ttaaggcaat taaaaatggt 6550

 tctcggctca gtgaactttc taaagtgcag atttctgagc tttcatttcc 6600

 tgcctgtaac acggttcatc ccgagttact ccctgagtct tcaggccacg 6650

 atggccaagg gcttgtgact tctgcaagcg acgtgactgg aaaccacgca 6700

 gcacttcaca gggatcctag tgtgttctct gctggtgatt ccccagggga 6750

 ggctccttct gcgctgttgc cagggccacc ccctggtcag cctgaagcca 6800

 ctcagctgac agggccaaaa cgggctggcc aggcagctct gtcagaacga 6850

 agccctgtgg ctgatcggaa gcagcctgtt cctccaggac gtgctgcgcg 6900

 ttcaagccag tctccaaaaa agccgttcaa tagtattatt gagcacctgt 6950

 cagtggtatt cccatgttac aacagcactg agcttgctgg ttttattaaa 7000

 aaagtgcgaa gcaaaaacaa gaactcactc tcaggattga gtattgatga 7050

 aattgtccaa agagtgacag aacacattct agatgaacag aaaaagaaaa 7100

 agccaaaccc aggaaaggac aagaggactt atgagcccag ctctgccacc 7150

 cccgtgacca ggtcctccca gggctcaccc tcggtggttg ttgcaccatc 7200

 acccaaaacc aaggggcaga aagcagaaga tgtccctgtg aggattgcac 7250

 tgggtgcaag ttcctgtgaa atatgccacg aggtgttcaa atcaaaaaac 7300

 gtgcgtgtgc tcaaatgtgg gcacaagtat cacaaagggt gctttaagca 7350

 gtggcttaaa gggcagagcg cttgcccggc ctgccagggt cgtgatctcc 7400

 tgacagaaga gtcaccttct ggaagaggct ggcccagtca gaatcaggag 7450

 ctgccttcct gctcttctag gtagtcacac ttcactaaag tgtcatccac 7500

 cagtgtgttg aatccgaaga atgacaattt tctaccactg gtgtaaaaaa 7550

 caaacatttg aagacccttg tgcattgtgt gtcacaaagc taaatacatg 7600

 gaaatcgtta atatcgctga tattaagtaa tttccccact ctgagtgaat 7650

 actttgatga ttgccaacag tggctaataa aatgacggct accacactca 7700

 tgggtcactg ggctgcgcag ggctctttga ggtgggtggc ttcttttgga 7750

 aagtactatg aacgtctcga agcagtattc tagtgataag aattcttaac 7800

 atagccaagc gccccacgtt tgttccccac gtttgttccc cttttctgtt 7850

 tgaaaaacct gttctggtag ctccacaaga gagatgatac tgacttttta 7900

 aattttttac aagagtctgt attcctgata tgcctatatt tttcctcaaa 7950

 gattctgcat tttaaggatg ggcataagca aactatattt taataattta 8000

 tagttaatgt taaaatattg gctgatttag accaaaagat tcaaatctcc 8050

 tctttgtgaa atcccatctg catttgattt tttattattt tatgttcccc 8100

 cgttagattg ttttaagtgt ttgcttttca tcttttatag atgtaatctg 8150

 attttcaaaa atcattaaca ctttttaatt agtatcgact aagacttttt 8200

 ccccctggaa tcgaggctgt gtgtccgtca tcccagcccc cggttggagc 8250

 ctgctctttg aactccgctg ccttccttag cagcttctgt cctcttctgt 8300

 gagtcagtca gcgagtgctt gggatccgca tccagccgtg ctgagcacac 8350

 aacaggctgt gtgtggaaat ggccaccacc attctccttc cccaccccac 8400

 cacaaaaaga gaagctgtgt ctttagacaa ccctgaggta tctgtgttac 8450

 aatcgttctg tgtttgatat ttgtgtaaag tatgcatgca gtcttgtact 8500

 gtgacctaag aacaaaactg taactgcatt agaaaccatg aaaaaattag 8550

 atattgtttt gtgactttta gacagtggta aatatagaac catgaattct 8600

 ggtcacattc catttctctc caacatgaag gatcaaaaaa tgtttttcaa 8650

 tgtgttcttt gttccactgg gaaacttaga gtcatgagtt tatgaggctg 8700

 gatttgggca cctttccttt gcctttggtt cactgtgagt tctgatgtcc 8750

 tagtgactta ggtcttagaa gctcacgcct tagtttgaaa cagattctcc 8800

 acggtggtcc ccaaaacact gtctgcatat ccataagaat tgaacgctat 8850

 gggtgttaac gtgcatgagg atcagtttgc agcagcaagt acaaaaggag 8900

 aagaggaaca tccgttgaat gagtgtgttt tgtacataac ttcagatact 8950

 tgtgaacatg ccttatattt gtccaacaac tgtcagaata aagaacattc 9000

 taaaatgag 9009

<210> 2279
<211> 2025
<212> PRT
<213> Homo sapien

<400> 2279
 Met Asp Asn Phe Ala Glu Gly Asp Phe Thr Val Ala Asp Tyr Ala
   1               5                  10                  15

 Leu Leu Glu Asp Cys Pro His Val Asp Asp Cys Val Phe Ala Ala
                  20                  25                  30

 Glu Phe Met Ser Asn Asp Tyr Val Arg Val Thr Gln Leu Tyr Cys
                  35                  40                  45

 Asp Gly Val Gly Val Gln Tyr Lys Asp Tyr Ile Gln Ser Glu Arg
                  50                  55                  60

 Asn Leu Glu Phe Asp Ile Cys Ser Ile Trp Cys Ser Lys Pro Ile
                  65                  70                  75

 Ser Val Leu Gln Asp Tyr Cys Asp Ala Ile Lys Ile Asn Ile Phe
                  80                  85                  90

 Trp Pro Leu Leu Phe Gln His Gln Asn Ser Ser Val Ile Ser Arg
                  95                 100                 105

 Leu His Pro Cys Val Asp Ala Asn Asn Ser Arg Ala Ser Glu Ile
                 110                 115                 120

 Asn Leu Lys Lys Leu Gln His Leu Glu Leu Met Glu Asp Ile Val
                 125                 130                 135

 Asp Leu Ala Lys Lys Val Ala Asn Asp Ser Phe Leu Ile Gly Gly
                 140                 145                 150

 Leu Leu Arg Ile Gly Cys Lys Ile Glu Asn Lys Ile Leu Ala Met
                 155                 160                 165

 Glu Glu Ala Leu Asn Trp Ile Lys Tyr Ala Gly Asp Val Thr Ile
                 170                 175                 180

 Leu Thr Lys Leu Gly Ser Ile Asp Asn Cys Trp Pro Met Leu Ser
                 185                 190                 195

 Ile Phe Phe Thr Glu Tyr Lys Tyr His Ile Thr Lys Ile Val Met
                 200                 205                 210

 Glu Asp Cys Asn Leu Leu Glu Glu Leu Lys Thr Gln Ser Cys Met
                 215                 220                 225

 Asp Cys Ile Glu Glu Gly Glu Leu Met Lys Met Lys Gly Asn Glu
                 230                 235                 240

 Glu Phe Ser Lys Glu Arg Phe Asp Ile Ala Ile Ile Tyr Tyr Thr
                 245                 250                 255

 Arg Ala Ile Glu Tyr Arg Pro Glu Asn Tyr Leu Leu Tyr Gly Asn
                 260                 265                 270

 Arg Ala Leu Cys Phe Leu Arg Thr Gly Gln Phe Arg Asn Ala Leu
                 275                 280                 285

 Gly Asp Gly Lys Arg Ala Thr Ile Leu Lys Asn Thr Trp Pro Lys
                 290                 295                 300

 Gly His Tyr Arg Tyr Cys Asp Ala Leu Ser Met Leu Gly Glu Tyr
                 305                 310                 315

 Asp Trp Ala Leu Gln Ala Asn Ile Lys Ala Gln Lys Leu Cys Lys
                 320                 325                 330

 Asn Asp Pro Glu Gly Ile Lys Asp Leu Ile Gln Gln His Val Lys
                 335                 340                 345

 Leu Gln Lys Gln Ile Glu Asp Leu Gln Gly Arg Thr Ala Asn Lys
                 350                 355                 360

 Asp Pro Ile Lys Ala Phe Tyr Glu Asn Arg Ala Tyr Thr Pro Arg
                 365                 370                 375

 Ser Leu Ser Ala Pro Ile Phe Thr Thr Ser Leu Asn Phe Val Glu
                 380                 385                 390

 Lys Glu Arg Asp Phe Arg Lys Ile Asn His Glu Met Ala Asn Gly
                 395                 400                 405

 Gly Asn Gln Asn Leu Lys Val Ala Asp Glu Ala Leu Lys Val Asp
                 410                 415                 420

 Asp Cys Asp Cys His Pro Glu Phe Ser Pro Pro Ser Ser Gln Pro
                 425                 430                 435

 Pro Lys His Lys Gly Lys Gln Lys Ser Arg Asn Asn Glu Ser Glu
                 440                 445                 450

 Lys Phe Ser Ser Ser Ser Pro Leu Thr Leu Pro Ala Asp Leu Lys
                 455                 460                 465

 Asn Ile Leu Glu Lys Gln Phe Ser Lys Ser Ser Arg Ala Ala His
                 470                 475                 480

 Gln Asp Phe Ala Asn Ile Met Lys Met Leu Arg Ser Leu Ile Gln
                 485                 490                 495

 Asp Gly Tyr Met Ala Leu Leu Glu Gln Arg Cys Arg Ser Ala Ala
                 500                 505                 510

 Gln Ala Phe Thr Glu Leu Leu Asn Gly Leu Asp Pro Gln Lys Ile
                 515                 520                 525

 Lys Gln Leu Asn Leu Ala Met Ile Asn Tyr Val Leu Val Val Tyr
                 530                 535                 540

 Gly Leu Ala Ile Ser Leu Leu Gly Ile Gly Gln Pro Glu Glu Leu
                 545                 550                 555

 Ser Glu Ala Glu Asn Gln Phe Lys Arg Ile Ile Glu His Tyr Pro
                 560                 565                 570

 Ser Glu Gly Leu Asp Cys Leu Ala Tyr Cys Gly Ile Gly Lys Val
                 575                 580                 585

 Tyr Leu Lys Lys Asn Arg Phe Leu Glu Ala Leu Asn His Phe Glu
                 590                 595                 600

 Lys Ala Arg Thr Leu Ile Tyr Arg Leu Pro Gly Val Leu Thr Trp
                 605                 610                 615

 Pro Thr Ser Asn Val Ile Ile Glu Glu Ser Gln Pro Gln Lys Ile
                 620                 625                 630

 Lys Met Leu Leu Glu Lys Phe Val Glu Glu Cys Lys Phe Pro Pro
                 635                 640                 645

 Val Pro Asp Ala Ile Cys Cys Tyr Gln Lys Cys His Gly Tyr Ser
                 650                 655                 660

 Lys Ile Gln Ile Tyr Ile Thr Asp Pro Asp Phe Lys Gly Phe Ile
                 665                 670                 675

 Arg Ile Ser Cys Cys Gln Tyr Cys Lys Ile Glu Phe His Met Asn
                 680                 685                 690

 Cys Trp Lys Lys Leu Lys Thr Thr Thr Phe Asn Asp Lys Ile Asp
                 695                 700                 705

 Lys Asp Phe Leu Gln Gly Ile Cys Leu Thr Pro Asp Cys Glu Gly
                 710                 715                 720

 Val Ile Ser Lys Ile Ile Ile Phe Ser Ser Gly Gly Glu Val Lys
                 725                 730                 735

 Cys Glu Phe Glu His Lys Val Ile Lys Glu Lys Val Pro Pro Arg
                 740                 745                 750

 Pro Ile Leu Lys Gln Lys Cys Ser Ser Leu Glu Lys Leu Arg Leu
                 755                 760                 765

 Lys Glu Asp Lys Lys Leu Lys Arg Lys Ile Gln Lys Lys Glu Ala
                 770                 775                 780

 Lys Lys Leu Ala Gln Glu Arg Met Glu Glu Asp Leu Arg Glu Ser
                 785                 790                 795

 Asn Pro Pro Lys Asn Glu Glu Gln Lys Glu Thr Val Asp Asn Val
                 800                 805                 810

 Gln Arg Cys Gln Phe Leu Asp Asp Arg Ile Leu Gln Cys Ile Lys
                 815                 820                 825

 Gln Tyr Ala Asp Lys Ile Lys Ser Gly Ile Gln Asn Thr Ala Met
                 830                 835                 840

 Leu Leu Lys Glu Leu Leu Ser Trp Lys Val Leu Ser Thr Glu Asp
                 845                 850                 855

 Tyr Thr Thr Cys Phe Ser Ser Arg Asn Phe Leu Asn Glu Ala Val
                 860                 865                 870

 Asp Tyr Val Ile Arg His Leu Ile Gln Glu Asn Asn Arg Val Lys
                 875                 880                 885

 Thr Arg Ile Phe Leu His Val Leu Ser Glu Leu Lys Glu Val Glu
                 890                 895                 900

 Pro Lys Leu Ala Ala Trp Ile Gln Lys Leu Asn Ser Phe Gly Leu
                 905                 910                 915

 Asp Ala Thr Gly Thr Phe Phe Ser Arg Tyr Gly Ala Ser Leu Lys
                 920                 925                 930

 Leu Leu Asp Phe Ser Ile Met Thr Phe Leu Trp Asn Glu Lys Tyr
                 935                 940                 945

 Gly His Lys Leu Asp Ser Ile Glu Gly Lys Gln Leu Asp Tyr Phe
                 950                 955                 960

 Ser Glu Pro Ala Ser Leu Lys Glu Ala Arg Cys Leu Ile Trp Leu
                 965                 970                 975

 Leu Glu Glu His Arg Asp Lys Phe Pro Ala Leu His Ser Ala Leu
                 980                 985                 990

 Asp Glu Phe Phe Asp Ile Met Asp Ser Arg Cys Thr Val Leu Arg
                 995                1000                1005

 Lys Gln Asp Ser Gly Glu Ala Pro Phe Ser Ser Thr Lys Val Lys
                1010                1015                1020

 Asn Lys Ser Lys Lys Lys Lys Pro Lys Asp Ser Lys Pro Met Leu
                1025                1030                1035

 Val Gly Ser Gly Thr Thr Ser Val Thr Ser Asn Asn Glu Ile Ile
                1040                1045                1050

 Thr Ser Ser Glu Asp His Ser Asn Arg Asn Ser Asp Ser Ala Gly
                1055                1060                1065

 Pro Phe Ala Val Pro Asp His Leu Arg Gln Asp Val Glu Glu Phe
                1070                1075                1080

 Glu Ala Leu Tyr Asp Gln His Ser Asn Glu Tyr Val Val Arg Asn
                1085                1090                1095

 Lys Lys Leu Trp Asp Met Asn Pro Lys Gln Lys Cys Ser Thr Leu
                1100                1105                1110

 Tyr Asp Tyr Phe Ser Gln Phe Leu Glu Glu His Gly Pro Leu Asp
                1115                1120                1125

 Met Ser Asn Lys Met Phe Ser Ala Glu Tyr Glu Phe Phe Pro Glu
                1130                1135                1140

 Glu Thr Arg Gln Ile Leu Glu Lys Ala Gly Gly Leu Lys Pro Phe
                1145                1150                1155

 Leu Leu Gly Cys Pro Arg Phe Val Val Ile Asp Asn Cys Ile Ala
                1160                1165                1170

 Leu Lys Lys Val Ala Ser Arg Leu Lys Lys Lys Arg Lys Lys Lys
                1175                1180                1185

 Asn Ile Lys Thr Lys Val Glu Glu Ile Ser Lys Ala Gly Glu Tyr
                1190                1195                1200

 Val Arg Val Lys Leu Gln Leu Asn Pro Ala Ala Arg Glu Phe Lys
                1205                1210                1215

 Pro Asp Val Lys Ser Lys Pro Val Ser Asp Ser Ser Ser Ala Pro
                1220                1225                1230

 Ala Phe Glu Asn Val Lys Pro Lys Pro Val Ser Ala Asn Ser Pro
                1235                1240                1245

 Lys Pro Ala Cys Glu Asp Val Lys Ala Lys Pro Val Ser Asp Asn
                1250                1255                1260

 Ser Ser Arg Gln Val Ser Glu Asp Gly Gln Pro Lys Gly Val Ser
                1265                1270                1275

 Ser Asn Ser Pro Lys Pro Gly Ser Glu Asp Ala Asn Tyr Lys Arg
                1280                1285                1290

 Val Ser Cys Asn Ser Pro Lys Pro Val Leu Glu Asp Val Lys Pro
                1295                1300                1305

 Thr Tyr Trp Ala Gln Ser His Leu Val Thr Gly Tyr Cys Thr Tyr
                1310                1315                1320

 Leu Pro Phe Gln Arg Phe Asp Ile Thr Gln Thr Pro Pro Ala Tyr
                1325                1330                1335

 Ile Asn Val Leu Pro Gly Leu Pro Gln Tyr Thr Ser Ile Tyr Thr
                1340                1345                1350

 Pro Leu Ala Ser Leu Ser Pro Glu Tyr Gln Leu Pro Arg Ser Val
                1355                1360                1365

 Pro Val Val Pro Ser Phe Val Ala Asn Asp Arg Ala Asp Lys Asn
                1370                1375                1380

 Ala Ala Ala Tyr Phe Glu Gly His His Leu Asn Ala Glu Asn Val
                1385                1390                1395

 Ala Gly His Gln Ile Ala Ser Glu Thr Gln Ile Leu Glu Gly Ser
                1400                1405                1410

 Leu Gly Ile Ser Val Lys Ser His Cys Ser Thr Gly Asp Ala His
                1415                1420                1425

 Thr Val Leu Ser Glu Ser Asn Arg Asn Asp Glu His Cys Gly Asn
                1430                1435                1440

 Ser Asn Asn Lys Cys Glu Val Ile Pro Glu Ser Thr Ser Ala Val
                1445                1450                1455

 Thr Asn Ile Pro His Val Gln Met Val Ala Ile Gln Val Ser Trp
                1460                1465                1470

 Asn Ile Ile His Gln Glu Val Asn Thr Glu Pro Tyr Asn Pro Phe
                1475                1480                1485

 Glu Glu Arg Gln Gly Glu Ile Ser Arg Ile Glu Lys Glu His Gln
                1490                1495                1500

 Val Leu Gln Asp Gln Leu Gln Glu Val Tyr Glu Asn Tyr Glu Gln
                1505                1510                1515

 Ile Lys Leu Lys Gly Leu Glu Glu Thr Arg Asp Leu Glu Glu Lys
                1520                1525                1530

 Leu Lys Arg His Leu Glu Glu Asn Lys Ile Ser Lys Thr Glu Leu
                1535                1540                1545

 Asp Trp Phe Leu Gln Asp Leu Glu Arg Glu Ile Lys Lys Trp Gln
                1550                1555                1560

 Gln Glu Lys Lys Glu Ile Gln Glu Arg Leu Lys Ser Leu Lys Lys
                1565                1570                1575

 Lys Ile Lys Lys Val Ser Asn Ala Ser Glu Met Tyr Thr Gln Lys
                1580                1585                1590

 Asn Asp Gly Lys Glu Lys Glu His Glu Leu His Leu Asp Gln Ser
                1595                1600                1605

 Leu Glu Ile Ser Asn Thr Leu Thr Asn Glu Lys Met Lys Ile Glu
                1610                1615                1620

 Glu Tyr Ile Lys Lys Gly Lys Glu Asp Tyr Glu Glu Ser His Gln
                1625                1630                1635

 Arg Ala Val Ala Ala Glu Val Ser Val Leu Glu Asn Trp Lys Glu
                1640                1645                1650

 Ser Glu Val Tyr Lys Leu Gln Ile Met Glu Ser Gln Ala Glu Ala
                1655                1660                1665

 Phe Leu Lys Lys Leu Gly Leu Ile Ser Arg Asp Pro Ala Ala Tyr
                1670                1675                1680

 Pro Asp Met Glu Ser Asp Ile Arg Ser Trp Glu Leu Phe Leu Ser
                1685                1690                1695

 Asn Val Thr Lys Glu Ile Glu Lys Ala Lys Ser Gln Phe Glu Glu
                1700                1705                1710

 Gln Ile Lys Ala Ile Lys Asn Gly Ser Arg Leu Ser Glu Leu Ser
                1715                1720                1725

 Lys Val Gln Ile Ser Glu Leu Ser Phe Pro Ala Cys Asn Thr Val
                1730                1735                1740

 His Pro Glu Leu Leu Pro Glu Ser Ser Gly His Asp Gly Gln Gly
                1745                1750                1755

 Leu Val Thr Ser Ala Ser Asp Val Thr Gly Asn His Ala Ala Leu
                1760                1765                1770

 His Arg Asp Pro Ser Val Phe Ser Ala Gly Asp Ser Pro Gly Glu
                1775                1780                1785

 Ala Pro Ser Ala Leu Leu Pro Gly Pro Pro Pro Gly Gln Pro Glu
                1790                1795                1800

 Ala Thr Gln Leu Thr Gly Pro Lys Arg Ala Gly Gln Ala Ala Leu
                1805                1810                1815

 Ser Glu Arg Ser Pro Val Ala Asp Arg Lys Gln Pro Val Pro Pro
                1820                1825                1830

 Gly Arg Ala Ala Arg Ser Ser Gln Ser Pro Lys Lys Pro Phe Asn
                1835                1840                1845

 Ser Ile Ile Glu His Leu Ser Val Val Phe Pro Cys Tyr Asn Ser
                1850                1855                1860

 Thr Glu Leu Ala Gly Phe Ile Lys Lys Val Arg Ser Lys Asn Lys
                1865                1870                1875

 Asn Ser Leu Ser Gly Leu Ser Ile Asp Glu Ile Val Gln Arg Val
                1880                1885                1890

 Thr Glu His Ile Leu Asp Glu Gln Lys Lys Lys Lys Pro Asn Pro
                1895                1900                1905

 Gly Lys Asp Lys Arg Thr Tyr Glu Pro Ser Ser Ala Thr Pro Val
                1910                1915                1920

 Thr Arg Ser Ser Gln Gly Ser Pro Ser Val Val Val Ala Pro Ser
                1925                1930                1935

 Pro Lys Thr Lys Gly Gln Lys Ala Glu Asp Val Pro Val Arg Ile
                1940                1945                1950

 Ala Leu Gly Ala Ser Ser Cys Glu Ile Cys His Glu Val Phe Lys
                1955                1960                1965

 Ser Lys Asn Val Arg Val Leu Lys Cys Gly His Lys Tyr His Lys
                1970                1975                1980

 Gly Cys Phe Lys Gln Trp Leu Lys Gly Gln Ser Ala Cys Pro Ala
                1985                1990                1995

 Cys Gln Gly Arg Asp Leu Leu Thr Glu Glu Ser Pro Ser Gly Arg
                2000                2005                2010

 Gly Trp Pro Ser Gln Asn Gln Glu Leu Pro Ser Cys Ser Ser Arg
                2015                2020                2025

<210> 2280
<211> 1142
<212> DNA
<213> Homo sapien

<400> 2280
 cttttccaag cggctgccga agatggcgga ggtgcaggtc ctggtgcttg 50

 atggtcgagg ccatctcctg ggccgcctgg cggccatcgt ggctaaacag 100

 gtactgctgg gccggaaggt ggtggtcgta cgctgtgaag gcatcaacat 150

 ttctggcaat ttctacagaa acaagttgaa gtacctggct ttcctccgca 200

 agcggatgaa caccaaccct tcccgaggcc cctaccactt ccgggccccc 250

 agccgcatct tctggcggac cgtgcgaggt atgctgcccc acaaaaccaa 300

 gcgaggccag gccgctctgg accgtctcaa ggtgtttgac ggcatcccac 350

 cgccctacga caagaaaaag cggatggtgg ttcctgctgc cctcaaggtc 400

 gtgcgtctga agcctacaag aaagtttgcc tatctggggc gcctggctca 450

 cgaggttggc tggaagtacc aggcagtgac agccaccctg gaggagaaga 500

 ggaaagagaa agccaagatc cactaccgga agaagaaaca gctcatgagg 550

 ctacggaaac aggccgagaa gaacgtggag aagaaaattg acaaatacac 600

 agaggtcctc aagacccacg gactcctggt ctgagcccaa taaagactgt 650

 taattcctca tgcgttgcct gcccttcctc cattgttgcc ctggaatgta 700

 cgggacccag gggcagcagc agtccaggtg ccacaggcag ccctgggaca 750

 taggaagctg ggagcaagga aagggtctta gtcactgcct cccgaagttg 800

 cttgaaagca ctcggagaat tgtgcaggtg tcatttatct atgaccaata 850

 ggaagagcaa ccagttacta tgagtgaaag ggagccagaa gactgattgg 900

 agggccctat cttgtgagtg gggcatctgt tggactttcc acctggtcat 950

 atactctgca gctgttagaa tgtgcaagca cttggggaca gcatgagctt 1000

 gctgttgtac acagggtatt tctagaagca gaaatagact gggaagatgc 1050

 acaaccaagg ggttacaggc atcgcccatg ctcctcacct gtattttgta 1100

 atcagaaata aattgctttt aaagaaaaaa aaaaaaaaaa aa 1142

<210> 2281
<211> 203
<212> PRT
<213> Homo sapien

<400> 2281
 Met Ala Glu Val Gln Val Leu Val Leu Asp Gly Arg Gly His Leu
   1               5                  10                  15

 Leu Gly Arg Leu Ala Ala Ile Val Ala Lys Gln Val Leu Leu Gly
                  20                  25                  30

 Arg Lys Val Val Val Val Arg Cys Glu Gly Ile Asn Ile Ser Gly
                  35                  40                  45

 Asn Phe Tyr Arg Asn Lys Leu Lys Tyr Leu Ala Phe Leu Arg Lys
                  50                  55                  60

 Arg Met Asn Thr Asn Pro Ser Arg Gly Pro Tyr His Phe Arg Ala
                  65                  70                  75

 Pro Ser Arg Ile Phe Trp Arg Thr Val Arg Gly Met Leu Pro His
                  80                  85                  90

 Lys Thr Lys Arg Gly Gln Ala Ala Leu Asp Arg Leu Lys Val Phe
                  95                 100                 105

 Asp Gly Ile Pro Pro Pro Tyr Asp Lys Lys Lys Arg Met Val Val
                 110                 115                 120

 Pro Ala Ala Leu Lys Val Val Arg Leu Lys Pro Thr Arg Lys Phe
                 125                 130                 135

 Ala Tyr Leu Gly Arg Leu Ala His Glu Val Gly Trp Lys Tyr Gln
                 140                 145                 150

 Ala Val Thr Ala Thr Leu Glu Glu Lys Arg Lys Glu Lys Ala Lys
                 155                 160                 165

 Ile His Tyr Arg Lys Lys Lys Gln Leu Met Arg Leu Arg Lys Gln
                 170                 175                 180

 Ala Glu Lys Asn Val Glu Lys Lys Ile Asp Lys Tyr Thr Glu Val
                 185                 190                 195

 Leu Lys Thr His Gly Leu Leu Val
                 200

<210> 2282
<211> 971
<212> DNA
<213> Homo sapien

<400> 2282
 taaaacttta ggaaattagt accagacttt tatattggtc aacagcaaaa 50

 tgaacattac tactcagcct ccaacacatg cagtttgcct ataccaggga 100

 tcctgtcaaa atatacacca cttatagctt cttaagtgca gttatcatag 150

 agcacagtcc ctgacatcac acagctgcag agatgaataa acaaagagga 200

 acctactcag aagtgagtct ggcccaggac ccaaagaggc agcaaaggaa 250

 acttaagggc aataaaatct ccatttcagg aaccaaacag gaaatattcc 300

 aagtagaatt aaaccttcaa aatgcttctt cggatcatca agggaatgac 350

 aagacatatc actgcaaagg tttactgcca cctccagaga agctcactgc 400

 tgaggtccta ggaatcattt gcattgtcct gatggccact gtgttaaaaa 450

 caatagttct tattccttgt attggagtac tggagcagaa caatttttcc 500

 ctgaatagaa gaatgcagaa agcacgtcat tgtggccatt gtcctgagga 550

 gtggattaca tattccaaca gttgttatta cattggtaag gaaagaagaa 600

 cttgggaaga aagagtttgc tggcctgtgc ttcgaagaac tctgatctgc 650

 tttctataga taatgaggaa gaaatggtaa gacgtaaatg tttcaacact 700

 ttactaaaag cttatttctg tcaatatcat atttgtagaa atcatccata 750

 tgtttataca tatatttact tcatatattt ttaagtctgt gtagtattca 800

 actgacttca taatattttt atattcatat actgttaatg cacatttggt 850

 tatttccagt tttgcttttc atggaaaccc atgcttctat aaatgttttt 900

 atcacaaaat aaatataaag aaaactaaaa aaaaaccaaa aaaaaaaaaa 950

 aaaaaggcgg ccgcgatata g 971

<210> 2283
<211> 158
<212> PRT
<213> Homo sapien

<400> 2283
 Met Asn Lys Gln Arg Gly Thr Tyr Ser Glu Val Ser Leu Ala Gln
   1               5                  10                  15

 Asp Pro Lys Arg Gln Gln Arg Lys Leu Lys Gly Asn Lys Ile Ser
                  20                  25                  30

 Ile Ser Gly Thr Lys Gln Glu Ile Phe Gln Val Glu Leu Asn Leu
                  35                  40                  45

 Gln Asn Ala Ser Ser Asp His Gln Gly Asn Asp Lys Thr Tyr His
                  50                  55                  60

 Cys Lys Gly Leu Leu Pro Pro Pro Glu Lys Leu Thr Ala Glu Val
                  65                  70                  75

 Leu Gly Ile Ile Cys Ile Val Leu Met Ala Thr Val Leu Lys Thr
                  80                  85                  90

 Ile Val Leu Ile Pro Cys Ile Gly Val Leu Glu Gln Asn Asn Phe
                  95                 100                 105

 Ser Leu Asn Arg Arg Met Gln Lys Ala Arg His Cys Gly His Cys
                 110                 115                 120

 Pro Glu Glu Trp Ile Thr Tyr Ser Asn Ser Cys Tyr Tyr Ile Gly
                 125                 130                 135

 Lys Glu Arg Arg Thr Trp Glu Glu Arg Val Cys Trp Pro Val Leu
                 140                 145                 150

 Arg Arg Thr Leu Ile Cys Phe Leu
                 155

<210> 2284
<211> 2435
<212> DNA
<213> Homo sapien

<400> 2284
 gcagcgccgc gactcgtgcg ggtaggcgtc tgcgctcggt ttgagggctc 50

 ggcgcggggt ttcctgttcc tccttctgcg cggctgcagc tcgggacttc 100

 ggcctgaccc agcccccatg gcttcagaag agctacagaa agatctagaa 150

 gaggtaaagg tgttgctgga aaaggctact aggaaaagag tacgtgatgc 200

 ccttacagct gaaaaatcca agattgagac agaaatcaag aacaagatgc 250

 aacagaaatc acagaagaaa gcagaacttc ttgataatga aaaaccagct 300

 gctgtggttg ctcccattac aacgggctat acggtgaaaa tcagtaatta 350

 tggatgggat cagtcagata agtttgtgaa aatctacatt accttaactg 400

 gagttcatca agttcccact gagaatgtgc aggtgcattt cacagagagg 450

 tcatttgatc ttttggtaaa gaatctaaat gggaagagtt actccatgat 500

 tgtgaacaat ctcttgaaac ccatctctgt ggaaggcagt tcaaaaaaag 550

 tcaagactga tacagttctt atattgtgta gaaagaaagt ggaaaacaca 600

 aggtgggatt acctgaccca ggttgaaaag gagtgcaaag aaaaagagaa 650

 gccctcctat gacactgaaa cagatcctag tgagggattg atgaatgttc 700

 taaagaaaat ttatgaagat ggagacgatg atatgaagcg aaccattaat 750

 aaagcctggg tggaatcaag agagaagcaa gccaaaggag acacggaatt 800

 ttgagacttt aaagtcgttt tgggaactgt gatgtgatgt ggaaatactg 850

 atgtttccag taagggaata ttggtgagct gcatatataa atttgacaga 900

 tagctattta catagccttc taagtaaagg caatgaattc tccatttcct 950

 actggaggat ttatttaaat aaaatatgct tattaaacac tcctgcaaag 1000

 atggttttat tagtaccctg gtcattttgt tcaaggaagg gttatattgc 1050

 attctcacgt gaaatataaa aagcaagtct tgcccaataa aaacgctaca 1100

 ttgtgtgtat tttttgttca gctaagaatt ggaaaagtat ttgcttgcct 1150

 tttaagttac tgacatcagc ttccaccagt gtaaaaattg agtaaaacct 1200

 gaagttttgc ataaaatgca aatcggtgcc tgtgcttgaa ggttgctgta 1250

 gagcatctga ccccttatta ccaccttaag caatgtatat gccatgcatt 1300

 accatgcact aattcaatca caggtgtttc tatctagatt taaatatatt 1350

 tgtcaatgaa tgtggaatag aaaatctaaa catgacaata atagacatat 1400

 ctttgtatgg taccagttag ttttgccgtg gatcagatgg tttataaaag 1450

 taataaccat aaagcaaaaa ataatttgaa agcccgtcta ttcctatgct 1500

 caataaagtt aagtttttct tcattagaac agttttatga tttatttgtc 1550

 taggagtatg tcagaaaaat caggctttta gtaggaatta ctcctattcc 1600

 ccctgaagtc aggaccagtg cctgtgatct ccattacttt attttcctgg 1650

 aggtattagc caacacagtt agatcagaga aagcaattga agccaggcat 1700

 gaaggctggc gcccgtaatc ccagctacta aggctggagg atcacttcag 1750

 cccaggagtt taaggctgca gtgagctatg atgatgccac tgtactgcag 1800

 cttgggtaac agattgagaa cctgtctcat taaaaaaaaa aaaaaaaaaa 1850

 aagccgttag acacacagga aaaatccaga agggtaaact aaactaaagc 1900

 tacaattaat atgggaattt ggaagaagtg gtaggattta aaatacagaa 1950

 acagtttatg tataggatag ctataagtaa atactgaaac acattatgcc 2000

 tctgtaattg gggttgacac atgaacagaa tagcagacac aatgcatatg 2050

 aaagttacag aatatggtaa aagtggggta aagatgggtt tttaatgata 2100

 ctaagataac tgaaaatagg catatagata tattccaagc cgcctgacga 2150

 tctaattgta aaaagtaaag catacaaata ctagaagaaa atggaggaaa 2200

 acgacattat atgtgactta aaacctagaa gaaataaata aaactattga 2250

 tcaattttaa ctacataaaa atgtttatag gacaagaaaa accccaccat 2300

 aacccaaggc aaacaatgta ttgacaggat tccaataatt aagaatactt 2350

 catacaaaaa gaaatgtaaa tgacctttaa catgtaaaga tgctcacctt 2400

 gttcagaaga gaataaacca gtgtttttac ctttc 2435

<210> 2285
<211> 228
<212> PRT
<213> Homo sapien

<400> 2285
 Met Ala Ser Glu Glu Leu Gln Lys Asp Leu Glu Glu Val Lys Val
   1               5                  10                  15

 Leu Leu Glu Lys Ala Thr Arg Lys Arg Val Arg Asp Ala Leu Thr
                  20                  25                  30

 Ala Glu Lys Ser Lys Ile Glu Thr Glu Ile Lys Asn Lys Met Gln
                  35                  40                  45

 Gln Lys Ser Gln Lys Lys Ala Glu Leu Leu Asp Asn Glu Lys Pro
                  50                  55                  60

 Ala Ala Val Val Ala Pro Ile Thr Thr Gly Tyr Thr Val Lys Ile
                  65                  70                  75

 Ser Asn Tyr Gly Trp Asp Gln Ser Asp Lys Phe Val Lys Ile Tyr
                  80                  85                  90

 Ile Thr Leu Thr Gly Val His Gln Val Pro Thr Glu Asn Val Gln
                  95                 100                 105

 Val His Phe Thr Glu Arg Ser Phe Asp Leu Leu Val Lys Asn Leu
                 110                 115                 120

 Asn Gly Lys Ser Tyr Ser Met Ile Val Asn Asn Leu Leu Lys Pro
                 125                 130                 135

 Ile Ser Val Glu Gly Ser Ser Lys Lys Val Lys Thr Asp Thr Val
                 140                 145                 150

 Leu Ile Leu Cys Arg Lys Lys Val Glu Asn Thr Arg Trp Asp Tyr
                 155                 160                 165

 Leu Thr Gln Val Glu Lys Glu Cys Lys Glu Lys Glu Lys Pro Ser
                 170                 175                 180

 Tyr Asp Thr Glu Thr Asp Pro Ser Glu Gly Leu Met Asn Val Leu
                 185                 190                 195

 Lys Lys Ile Tyr Glu Asp Gly Asp Asp Asp Met Lys Arg Thr Ile
                 200                 205                 210

 Asn Lys Ala Trp Val Glu Ser Arg Glu Lys Gln Ala Lys Gly Asp
                 215                 220                 225

 Thr Glu Phe


<210> 2286
<211> 5600
<212> DNA
<213> Homo sapien

<400> 2286
 ggagtgggcc aggccgccag ccccgccagc cccgccagcc ccgccagccc 50

 cgcgatggct tgggccgcgc tcctcggcct cctggccgca ctgttgctgc 100

 tgctgctact gagccgccgc cgcacgcggc gacctggtga gcctcccctg 150

 gacctgggca gcatcccctg gttggggtat gccttggact ttggaaaaga 200

 tgctgccagc ttcctcacga ggatgaagga gaagcacggt gacatcttta 250

 ctatactggt tgggggcagg tatgtcaccg ttctcctgga cccacactcc 300

 tacgacgcgg tggtgtggga gcctcgcacc aggctcgact tccatgccta 350

 tgccatcttc ctcatggaga ggatttttga tgtgcagctt ccacattaca 400

 gccccagtga tgaaaaggcc aggatgaaac tgactcttct ccacagagag 450

 ctccaggcac tcacagaagc catgtatacc aacctccatg cagtgctgtt 500

 gggcgatgct acagaagcag gcagtggctg gcacgagatg ggtctcctcg 550

 acttctccta cagcttcctg ctcagagccg gctacctgac tctttacgga 600

 attgaggcgc tgccacgcac ccatgaaagc caggcccagg accgcgtcca 650

 ctcagctgat gtcttccaca cctttcgcca gctcgaccgg ctgctcccca 700

 aactggcccg tggctccctg tcagtggggg acaaggacca catgtgcagt 750

 gtcaaaagtc gcctgtggaa gctgctatcc ccagccaggc tggccaggcg 800

 ggcccaccgg agcaaatggc tggagagtta cctgctgcac ctggaggaga 850

 tgggtgtgtc agaggagatg caggcacggg ccctggtgct gcagctgtgg 900

 gccacacagg ggaatatggg tcccgctgcc ttctggctcc tgctcttcct 950

 tctcaagaat cctgaagccc tggctgctgt ccgcggagag ctcgagagta 1000

 tcctttggca agcggagcag cctgtctcgc agacgaccac tctcccacag 1050

 aaggttctag acagcacacc tgtgcttgat agcgtgctga gtgagagcct 1100

 caggcttaca gctgccccct tcatcacccg cgaggttgtg gtggacctgg 1150

 ccatgcccat ggcagacggg cgagaattca acctgcgacg tggtgaccgc 1200

 ctcctcctct tccccttcct gagcccccag agagacccag aaatctacac 1250

 agacccagag gtatttaaat acaaccgatt cctgaaccct gacggatcag 1300

 agaagaaaga cttttacaag gatgggaaac ggctgaagaa ttacaacatg 1350

 ccctgggggg cggggcacaa tcactgcctg gggaggagtt atgcggtcaa 1400

 cagcatcaaa caatttgtgt tccttgtgct ggtgcacttg gacttggagc 1450

 tgatcaacgc agatgtggag atccctgagt ttgacctcag caggtacggc 1500

 ttcggtctga tgcagccgga acacgacgtg cccgtccgct accgcatccg 1550

 cccatgacac agggagcaga tggatccacg tgctcgcctc tgcccagcct 1600

 gccccagcct gccccagcct cccagctttc tgtgtgcaca gttggcccgg 1650

 gtgcaggtgc tagcattacc acttccctgc ttttctccca gaaggctggg 1700

 tccaggggag ggaaaagcta agagggtgaa caaagaaaag acattgaaag 1750

 ctctatggat tatccactgc aaagttttct ttccaaaatc aggctttgtc 1800

 tgctcccaat tcacctcgtt actctcacct cgtgatatcc acaaatgcta 1850

 ttcagataag gcagaactag gagtcttcac tgctctgccc ccaactcccg 1900

 gaggtgtcac cttcctagtt cttatgagct agcatggccc gggccttatc 1950

 cagtcaaagc ggatgctggc cacagaaagg ccactcagga tgtcctttgt 2000

 gtccattgat gtcattcagc agtcagtccc ccaataatcc ttaaactagc 2050

 taaaaccaaa ggagtccctt agaagatctg cttccctggg gccccatttg 2100

 ccagattgcc ccattgctca cactacttga gaaaatgcag gagagcttcc 2150

 cccaaggctg atgcattccc ggtgcagaac aggggcaccc tccaaacact 2200

 gggctctgag gagtggagtt ctctgttcta gagtgacagg caccagatgg 2250

 gatgggcttt ctcagtgtca gcactcaggt agggagctaa ggaagacaca 2300

 gcccagacaa gatggctgga aggagccagc caggactcct tagactgatc 2350

 aagccaaaaa agaaggtgcc gatttcatgc attctagtgc agaagcccca 2400

 actgtgatca cgatccagtc tgcagacgtg ttttgtttgg acttcactta 2450

 aaaaaatgcc ttagttgtta tcatctttgg gagagttcat tcaaaatgtc 2500

 cagcttctct tgaaaacttg gtatatctgg ccacactggg ctcacattcc 2550

 caagggtaac tcttggccag agctgagtgg cagccgcctc ccttatgcag 2600

 gacatgtgct ctcggcttca ccagggttct gaccgggtct gcttctgcat 2650

 tcacagcgcc tcctggacct gaaggcatct gagtgtgaga ccctgttcta 2700

 actcttagaa gtgacattgt aagaggtggt ggggaccagc taattggtcc 2750

 aacccagcct gagtgcacca ccctttgaac aaatgtatca gtgatgaaaa 2800

 tttgcctttg ccccggcttg cctgtaatcc cagcactttg ggaggccgag 2850

 gtgggcggat cacttgaggt cgggagttca agaccagcct ggccaacatg 2900

 gcgaaacccc gtctctacta aacataaaaa aattagtcag gtgtggcggt 2950

 gcgtgcctgt aatcccagct attcaggagg ctgaggcacc agaattgctt 3000

 gaacccagga ggtggaggtt gcagtgaact gagactgcgc cacggcactc 3050

 cagcctgggc gacagagcaa gactctgtct caataaataa ataattaatt 3100

 aaaataaaaa acagcttaaa gagaaaaatg gcctgcaaac cttttttatg 3150

 atgctatttt tattaatata aagtcctgtt tattgagacc ctttaaatgc 3200

 ctgcgagaga ccctacagac agtatgtcta ctcctcacag catctctatg 3250

 aagagaagga gggttgtgcc cacttcatag atgagaaaac tgagaggtga 3300

 ggtgacttgc ctggggccac atagctcata agctgtagaa ctctgcaggc 3350

 agatttactg tcccaggagc aaatgctgga tgagcaactc ctgttctttg 3400

 ggctcaaggg gactggtgat gggacaattc ttctcgactt caggagctga 3450

 cagagccaga ggcacctaaa cttgggtaca tcttgtaaga cacataatga 3500

 ggtccctcta gctttagctg gagggagata aaagaacccc agacctctga 3550

 atgtcccaga ggctagtctc ttctcagagc agcactgggg tttgggggct 3600

 tccctgggcc tcagcctcca ggcaccccca ggattcccag agagacgctg 3650

 tgattggcag gaggcaggat atccccaggg aaacccatct tcacgcctgg 3700

 gtgaccccca ctgccgcctc cttcttaact ctgcaggaaa tcagagctgg 3750

 cagcctccag tgggaggaca gagccggttt ccgtggcaac cctcagctgc 3800

 ctcatcgtgg ctgggaaggg aaggaagcaa gccggcagaa atagctatgg 3850

 aaggtcttgc gcaggctgca accctggtgt gctgggcgaa aacccttatg 3900

 actcccccct tccaaatcag gctgggttgt cactgagact agattctcac 3950

 ctgccttcaa agaagggcca attcccttta aaggtcgcac ctccttggaa 4000

 ccacagtcat tagtgaatta cactcaagga aaagatgtgc tcccaccagg 4050

 cagctccagc tgttacctga gatactgaag tgcagctcag gagacgatta 4100

 tttaaacctg cccttgtttt aatcgttatt tttctcttta aaaaaaatag 4150

 aagctataaa gaaaagaggg agagatgagt gggttagcta cctgctatgc 4200

 gctagttagg aagttacctg gatgccattg tatttcttca tcccttgctt 4250

 aagaatcaaa attactggac atatgttagg aatactcttt ctttctttct 4300

 ttctttttaa gctcagtggc aagaatgaaa tactcttttt tttttttttt 4350

 ttttgagatg gagtctcgct ctgctgccca ggctagagtg cagtggcgtg 4400

 atctcggctc actgcaagct ctgcctcccg tgttcacacc attctcctgc 4450

 ctcagcctcc tgagtagctg ggactacagg cacccgccac cacacccggc 4500

 taatttttgg atttttagta gagatgggat ttcaccgtat tagccaggat 4550

 ggtcttgatc tcctgagctc gtgatctgcc cgcctcggcc tcccaaagtg 4600

 ctgggattac aggtgtgagc caccgcgccc agccaagaat aaaatactct 4650

 taagttgatc taatgaagtg tttccttacc attgtgatta ttgttactat 4700

 tatttgctat attttaatat tgttgtttac caaatattct cctttaaaca 4750

 gactcgcttt ttaaactttt tttttttttt ttgagacgga gtttcacgct 4800

 tattgcccag gctggagtgc aatggcacga tctcagctca ccacaacctc 4850

 cacctcctgg gtttaagcaa tgcttctgcc tcagcttccc aagtagctga 4900

 gattacaggc gcacaccacc acgcccaact gatttttgta tttttagtag 4950

 agacggggtt tccccatgtt ggtcaggctg gtctcgaact cctgacctcg 5000

 tgatttgcct gcctgggcct cccaaagtgc taggattaca ggcatgagcc 5050

 accatgcccg gcctaaactt tgtttttaaa atgaactttt tttcccccca 5100

 attgctgcca atagtggata acatgtatca ctcactgcca aaaatagaaa 5150

 gtgaccatga aaaataaatt cgctggggaa gggggctcca tgctggtgtg 5200

 gccaaggctg agagctctct cttctctgtt acaaaacgag ataagcaagt 5250

 gttagaattg ccttaaggcc acactggcat ctccctgacc ttctccaggg 5300

 acagaagcag gagtaagttt ctcatcccat gggcgaccag ggccatctcc 5350

 tcccaccagt ggcccccact cacagggagc tggcaatgcc ctacctgcct 5400

 gttctccaga tggagaaaca ggctctgaga tttcacaggt cttgcccaaa 5450

 gtcattgatt ttgatgatta aaaagaataa acacagtgtt tcctgagtag 5500

 cagtgattgt tatgccttgc tattttaata aagattctat tttcgtataa 5550

 cattgtcaag tggaaacatg ctgaaatcta ttaaaccatc tttgtttgtg 5600

<210> 2287
<211> 500
<212> PRT
<213> Homo sapien

<400> 2287
 Met Ala Trp Ala Ala Leu Leu Gly Leu Leu Ala Ala Leu Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Ser Arg Arg Arg Thr Arg Arg Pro Gly Glu Pro
                  20                  25                  30

 Pro Leu Asp Leu Gly Ser Ile Pro Trp Leu Gly Tyr Ala Leu Asp
                  35                  40                  45

 Phe Gly Lys Asp Ala Ala Ser Phe Leu Thr Arg Met Lys Glu Lys
                  50                  55                  60

 His Gly Asp Ile Phe Thr Ile Leu Val Gly Gly Arg Tyr Val Thr
                  65                  70                  75

 Val Leu Leu Asp Pro His Ser Tyr Asp Ala Val Val Trp Glu Pro
                  80                  85                  90

 Arg Thr Arg Leu Asp Phe His Ala Tyr Ala Ile Phe Leu Met Glu
                  95                 100                 105

 Arg Ile Phe Asp Val Gln Leu Pro His Tyr Ser Pro Ser Asp Glu
                 110                 115                 120

 Lys Ala Arg Met Lys Leu Thr Leu Leu His Arg Glu Leu Gln Ala
                 125                 130                 135

 Leu Thr Glu Ala Met Tyr Thr Asn Leu His Ala Val Leu Leu Gly
                 140                 145                 150

 Asp Ala Thr Glu Ala Gly Ser Gly Trp His Glu Met Gly Leu Leu
                 155                 160                 165

 Asp Phe Ser Tyr Ser Phe Leu Leu Arg Ala Gly Tyr Leu Thr Leu
                 170                 175                 180

 Tyr Gly Ile Glu Ala Leu Pro Arg Thr His Glu Ser Gln Ala Gln
                 185                 190                 195

 Asp Arg Val His Ser Ala Asp Val Phe His Thr Phe Arg Gln Leu
                 200                 205                 210

 Asp Arg Leu Leu Pro Lys Leu Ala Arg Gly Ser Leu Ser Val Gly
                 215                 220                 225

 Asp Lys Asp His Met Cys Ser Val Lys Ser Arg Leu Trp Lys Leu
                 230                 235                 240

 Leu Ser Pro Ala Arg Leu Ala Arg Arg Ala His Arg Ser Lys Trp
                 245                 250                 255

 Leu Glu Ser Tyr Leu Leu His Leu Glu Glu Met Gly Val Ser Glu
                 260                 265                 270

 Glu Met Gln Ala Arg Ala Leu Val Leu Gln Leu Trp Ala Thr Gln
                 275                 280                 285

 Gly Asn Met Gly Pro Ala Ala Phe Trp Leu Leu Leu Phe Leu Leu
                 290                 295                 300

 Lys Asn Pro Glu Ala Leu Ala Ala Val Arg Gly Glu Leu Glu Ser
                 305                 310                 315

 Ile Leu Trp Gln Ala Glu Gln Pro Val Ser Gln Thr Thr Thr Leu
                 320                 325                 330

 Pro Gln Lys Val Leu Asp Ser Thr Pro Val Leu Asp Ser Val Leu
                 335                 340                 345

 Ser Glu Ser Leu Arg Leu Thr Ala Ala Pro Phe Ile Thr Arg Glu
                 350                 355                 360

 Val Val Val Asp Leu Ala Met Pro Met Ala Asp Gly Arg Glu Phe
                 365                 370                 375

 Asn Leu Arg Arg Gly Asp Arg Leu Leu Leu Phe Pro Phe Leu Ser
                 380                 385                 390

 Pro Gln Arg Asp Pro Glu Ile Tyr Thr Asp Pro Glu Val Phe Lys
                 395                 400                 405

 Tyr Asn Arg Phe Leu Asn Pro Asp Gly Ser Glu Lys Lys Asp Phe
                 410                 415                 420

 Tyr Lys Asp Gly Lys Arg Leu Lys Asn Tyr Asn Met Pro Trp Gly
                 425                 430                 435

 Ala Gly His Asn His Cys Leu Gly Arg Ser Tyr Ala Val Asn Ser
                 440                 445                 450

 Ile Lys Gln Phe Val Phe Leu Val Leu Val His Leu Asp Leu Glu
                 455                 460                 465

 Leu Ile Asn Ala Asp Val Glu Ile Pro Glu Phe Asp Leu Ser Arg
                 470                 475                 480

 Tyr Gly Phe Gly Leu Met Gln Pro Glu His Asp Val Pro Val Arg
                 485                 490                 495

 Tyr Arg Ile Arg Pro
                 500

<210> 2288
<211> 1544
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1358
<223> Unknown base

<400> 2288
 gcacgagttg ggaggtgtag cgcggctctg aacgcgctga gggccgttga 50

 gtgtcgcagg cggcgagggc gcgagtgagg agcagaccca ggcatcgcgc 100

 gccgagaagg ccgggcgtcc ccacactgaa ggtccggaaa ggcgacttcc 150

 gggggctttg gcacctggcg gaccctcccg gagcgtcggc acctgaacgc 200

 gaggcgctcc attgcgcgtg cgcgttgagg ggcttcccgc acctgatcgc 250

 gagaccccaa cggctggtgg cgtcgcctgc gcgtctcggc tgagctggcc 300

 atggcgcagc tgtgcgggct gaggcggagc cgggcgtttc tcgccctgct 350

 gggatcgctg ctcctctctg gggtcctggc ggccgaccga gaacgcagca 400

 tccacgactt ctgcctggtg tcgaaggtgg tgggcagatg ccgggcctcc 450

 atgcctaggt ggtggtacaa tgtcactgac ggatcctgcc agctgtttgt 500

 gtatgggggc tgtgacggaa acagcaataa ttacctgacc aaggaggagt 550

 gcctcaagaa atgtgccact gtcacagaga atgccacggg tgacctggcc 600

 accagcagga atgcagcgga ttcctctgtc ccaagtgctc ccagaaggca 650

 ggattctgaa gaccactcca gcgatatgtt caactatgaa gaatactgca 700

 ccgccaacgc agtcactggg ccttgccgtg catccttccc acgctggtac 750

 tttgacgtgg agaggaactc ctgcaataac ttcatctatg gaggctgccg 800

 gggcaataag aacagctacc gctctgagga ggcctgcatg ctccgctgct 850

 tccgccagca ggagaatcct cccctgcccc ttggctcaaa ggtggtggtt 900

 ctggcggggc tgttcgtgat ggtgttgatc ctcttcctgg gagcctccat 950

 ggtctacctg atccgggtgg cacggaggaa ccaggagcgt gccctgcgca 1000

 ccgtctggag ctccggagat gacaaggagc agctggtgaa gaacacatat 1050

 gtcctgtgac cgccctgtcg ccaagaggac tggggaaggg aggggagact 1100

 atgtgtgagc tttttttaaa tagagggatt gactcggatt tgagtgatca 1150

 ttagggctga ggtctgtttc tctgggaggt aggacggctg cttcctggtc 1200

 tggcagggat gggtttgctt tggaaatcct ctaggaggct cctcctcgca 1250

 tggcctgcag tctggcagca gccccgagtt gtttcctcgc tgatcgattt 1300

 ctttcctcca ggtagagttt tctttgctta tgttgaattc cattgcctcc 1350

 ttttctcnat cacagaagtg atgttggaat cgtttctttt gtttgtctga 1400

 tttatggttt ttttaagtat aaacaaaagt tttttattag cattctgaaa 1450

 gaaggaaagt aaaatgtaca agtttaataa aaaggggcct tcccctttag 1500

 aataaatttc cagcatgttg ctttcaaaaa aaaaaaaaaa aaaa 1544

<210> 2289
<211> 252
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1358
<223> Unknown amino acid

<400> 2289
 Met Ala Gln Leu Cys Gly Leu Arg Arg Ser Arg Ala Phe Leu Ala
   1               5                  10                  15

 Leu Leu Gly Ser Leu Leu Leu Ser Gly Val Leu Ala Ala Asp Arg
                  20                  25                  30

 Glu Arg Ser Ile His Asp Phe Cys Leu Val Ser Lys Val Val Gly
                  35                  40                  45

 Arg Cys Arg Ala Ser Met Pro Arg Trp Trp Tyr Asn Val Thr Asp
                  50                  55                  60

 Gly Ser Cys Gln Leu Phe Val Tyr Gly Gly Cys Asp Gly Asn Ser
                  65                  70                  75

 Asn Asn Tyr Leu Thr Lys Glu Glu Cys Leu Lys Lys Cys Ala Thr
                  80                  85                  90

 Val Thr Glu Asn Ala Thr Gly Asp Leu Ala Thr Ser Arg Asn Ala
                  95                 100                 105

 Ala Asp Ser Ser Val Pro Ser Ala Pro Arg Arg Gln Asp Ser Glu
                 110                 115                 120

 Asp His Ser Ser Asp Met Phe Asn Tyr Glu Glu Tyr Cys Thr Ala
                 125                 130                 135

 Asn Ala Val Thr Gly Pro Cys Arg Ala Ser Phe Pro Arg Trp Tyr
                 140                 145                 150

 Phe Asp Val Glu Arg Asn Ser Cys Asn Asn Phe Ile Tyr Gly Gly
                 155                 160                 165

 Cys Arg Gly Asn Lys Asn Ser Tyr Arg Ser Glu Glu Ala Cys Met
                 170                 175                 180

 Leu Arg Cys Phe Arg Gln Gln Glu Asn Pro Pro Leu Pro Leu Gly
                 185                 190                 195

 Ser Lys Val Val Val Leu Ala Gly Leu Phe Val Met Val Leu Ile
                 200                 205                 210

 Leu Phe Leu Gly Ala Ser Met Val Tyr Leu Ile Arg Val Ala Arg
                 215                 220                 225

 Arg Asn Gln Glu Arg Ala Leu Arg Thr Val Trp Ser Ser Gly Asp
                 230                 235                 240

 Asp Lys Glu Gln Leu Val Lys Asn Thr Tyr Val Leu
                 245                 250

<210> 2290
<211> 1320
<212> DNA
<213> Homo sapien

<400> 2290
 ggggaaacaa cctgctccgt ggagcgcctg aaacaccagt ctttggggcc 50

 agtgcctcag tttcaatcca ggtaaccttt aaatgaaact tgcctaaaat 100

 cttaggtcat acacagaaga gactccaatc gacaagaagc tggaaaagaa 150

 tgatgttgtc cttaaacaac ctacagaata tcatctataa cccggtaatc 200

 ccgtatgttg gcaccattcc cgatcagctg gatcctggaa ctttgattgt 250

 gatatgtggg catgttccta gtgacgcaga cagattccag gtggatctgc 300

 agaatggcag cagtgtgaaa cctcgagccg atgtggcctt tcatttcaat 350

 cctcgtttca aaagggccgg ctgcattgtt tgcaatactt tgataaatga 400

 aaaatgggga cgggaagaga tcacctatga cacgcctttc aaaagagaaa 450

 agtcttttga gatcgtgatt atggtgctaa aggacaaatt ccaggtggct 500

 gtaaatggaa aacatactct gctctatggc cacaggatcg gcccagagaa 550

 aatagacact ctgggcattt atggcaaagt gaatattcac tcaattggtt 600

 ttagcttcag ctcggactta caaagtaccc aagcatctag tctggaactg 650

 acagagataa gtagagaaaa tgttccaaag tctggcacgc cccagcttcc 700

 tagtaataga ggaggagaca tttctaaaat cgcacccaga actgtctaca 750

 ccaagagcaa agattcgact gtcaatcaca ctttgacttg caccaaaata 800

 ccacctatga actatgtgtc aaagagcctg ccattcgctg caaggttgaa 850

 cacccccatg ggccctggac gaactgtcgt cgttaaagga gaagtgaatg 900

 caaatgccaa aagctttaat gttgacctac tagcaggaaa atcaaaggat 950

 attgctctac acttgaaccc acgcctgaat attaaagcat ttgtaagaaa 1000

 ttcttttctt caggagtcct ggggagaaga agagagaaat attacctctt 1050

 tcccatttag tcctgggatg tactttgaga tgataattta ctgtgatgtt 1100

 agagaattca aggttgcagt aaatggcgta cacagcctgg agtacaaaca 1150

 cagatttaaa gagctcagca gtattgacac gctggaaatt aatggagaca 1200

 tccacttact ggaagtaagg agctggtagc ctacctacac agctgctaca 1250

 aaaaccaaaa tacagaatgg cttctgtgat actggccttg caaaaaaaaa 1300

 aaaaaaaaaa aaaaaaaaaa 1320

<210> 2291
<211> 358
<212> PRT
<213> Homo sapien

<400> 2291
 Met Leu Ser Leu Asn Asn Leu Gln Asn Ile Ile Tyr Asn Pro Val
   1               5                  10                  15

 Ile Pro Tyr Val Gly Thr Ile Pro Asp Gln Leu Asp Pro Gly Thr
                  20                  25                  30

 Leu Ile Val Ile Cys Gly His Val Pro Ser Asp Ala Asp Arg Phe
                  35                  40                  45

 Gln Val Asp Leu Gln Asn Gly Ser Ser Val Lys Pro Arg Ala Asp
                  50                  55                  60

 Val Ala Phe His Phe Asn Pro Arg Phe Lys Arg Ala Gly Cys Ile
                  65                  70                  75

 Val Cys Asn Thr Leu Ile Asn Glu Lys Trp Gly Arg Glu Glu Ile
                  80                  85                  90

 Thr Tyr Asp Thr Pro Phe Lys Arg Glu Lys Ser Phe Glu Ile Val
                  95                 100                 105

 Ile Met Val Leu Lys Asp Lys Phe Gln Val Ala Val Asn Gly Lys
                 110                 115                 120

 His Thr Leu Leu Tyr Gly His Arg Ile Gly Pro Glu Lys Ile Asp
                 125                 130                 135

 Thr Leu Gly Ile Tyr Gly Lys Val Asn Ile His Ser Ile Gly Phe
                 140                 145                 150

 Ser Phe Ser Ser Asp Leu Gln Ser Thr Gln Ala Ser Ser Leu Glu
                 155                 160                 165

 Leu Thr Glu Ile Ser Arg Glu Asn Val Pro Lys Ser Gly Thr Pro
                 170                 175                 180

 Gln Leu Pro Ser Asn Arg Gly Gly Asp Ile Ser Lys Ile Ala Pro
                 185                 190                 195

 Arg Thr Val Tyr Thr Lys Ser Lys Asp Ser Thr Val Asn His Thr
                 200                 205                 210

 Leu Thr Cys Thr Lys Ile Pro Pro Met Asn Tyr Val Ser Lys Ser
                 215                 220                 225

 Leu Pro Phe Ala Ala Arg Leu Asn Thr Pro Met Gly Pro Gly Arg
                 230                 235                 240

 Thr Val Val Val Lys Gly Glu Val Asn Ala Asn Ala Lys Ser Phe
                 245                 250                 255

 Asn Val Asp Leu Leu Ala Gly Lys Ser Lys Asp Ile Ala Leu His
                 260                 265                 270

 Leu Asn Pro Arg Leu Asn Ile Lys Ala Phe Val Arg Asn Ser Phe
                 275                 280                 285

 Leu Gln Glu Ser Trp Gly Glu Glu Glu Arg Asn Ile Thr Ser Phe
                 290                 295                 300

 Pro Phe Ser Pro Gly Met Tyr Phe Glu Met Ile Ile Tyr Cys Asp
                 305                 310                 315

 Val Arg Glu Phe Lys Val Ala Val Asn Gly Val His Ser Leu Glu
                 320                 325                 330

 Tyr Lys His Arg Phe Lys Glu Leu Ser Ser Ile Asp Thr Leu Glu
                 335                 340                 345

 Ile Asn Gly Asp Ile His Leu Leu Glu Val Arg Ser Trp
                 350                 355

<210> 2292
<211> 2298
<212> DNA
<213> Homo sapien

<400> 2292
 tcggccgagc ccagagacag ccagttcctc tcccgccgcg ccgggccgcg 50

 tgccgctcgc tccccggccg tggcgcctcc gggccagacg cgctgcagcc 100

 tccagcccgc ggcaagcggg cggggcggcc gcgccacccc cggccccgcg 150

 ccagcagccc ctcgccgcgc gtccagcgtt cccggccagc agcctcccca 200

 tacgcagtcc tgctggaccg ccccgtcgcg ccccccactc tgaactcaag 250

 tcaccgtgga gctccgccgc cccgaaactt tcacgcgagc gggaaatatg 300

 ggatgtataa aatcaaaagg gaaagacagc ttgagtgacg atggagtaga 350

 tttgaagact caaccagtac gtaatactga aagaactatt tatgtgagag 400

 atccaacgtc caataaacag caaaggccag ttccagaatc tcagctttta 450

 cctggacaga ggtttcaaac taaagatcca gaggaacaag gagacattgt 500

 ggtagccttg tacccctatg atggcatcca cccggacgac ttgtctttca 550

 agaaaggaga gaagatgaaa gtcctggagg agcatggaga atggtggaaa 600

 gcaaagtccc ttttaacaaa aaaagaaggc ttcatcccca gcaactatgt 650

 ggccaaactc aacaccttag aaacagaaga gtggtttttc aaggatataa 700

 ccaggaagga cgcagaaagg cagcttttgg caccaggaaa tagcgctgga 750

 gctttcctta ttagagaaag tgaaacatta aaaggaagct tctctctgtc 800

 tgtcagagac tttgaccctg tgcatggtga tgttattaag cactacaaaa 850

 ttagaagtct ggataatggg ggctattaca tctctccacg aatcactttt 900

 ccctgtatca gcgacatgat taaacattac caaaagcagg cagatggctt 950

 gtgcagaaga ttggagaagg cttgtattag tcccaagcca cagaagccat 1000

 gggataaaga tgcctgggag atcccccggg agtccatcaa gttggtgaaa 1050

 aggcttggcg ctgggcagtt tggggaagtc tggatgggtt actataacaa 1100

 cagtaccaag gtggctgtga aaaccctgaa gccaggaact atgtctgtgc 1150

 aagccttcct ggaagaagcc aacctcatga agaccctgca gcatgacaag 1200

 ctcgtgaggc tctacgctgt ggtcaccagg gaggagccca tttacatcat 1250

 caccgagtac atggccaagg gcagtttgct ggatttcctg aagagcgatg 1300

 aaggtggcaa agtgctgctt ccaaagctca ttgacttttc tgctcagatt 1350

 gcagagggaa tggcatacat cgagcggaag aactacattc accgggacct 1400

 gcgagcagct aatgttctgg tctccgagtc actaatgtgc aaaattgcag 1450

 attttggcct tgctagagta attgaagata atgagtacac agcaagggaa 1500

 ggtgctaagt tccctattaa gtggacggct ccagaagcaa tcaactttgg 1550

 atgtttcact attaagtctg atgtgtggtc ctttggaatc ctcctatacg 1600

 aaattgtcac ctatgggaaa attccctacc cagggagaac taatgccgac 1650

 gtgatgaccg ccctgtccca gggctacagg atgccccgtg tggagaactg 1700

 cccagatgag ctctatgaca ttatgaaaat gtgctggaaa gaaaaggcag 1750

 aagagagacc aacgtttgac tacttacaga gcgtcctgga tgatttctac 1800

 acagccacgg aagggcaata ccagcagcag ccttagagca cagggagacc 1850

 cgtccatttg gcaggggtgg ctgcctcatt tagagaggaa aagtaaccat 1900

 cactggttgc acttatgatt tcatgtgcgg ggatcatctg ccgtgcctgg 1950

 atcctgaaat agaggctaaa ttactcagga agaacaccct ctaaatggga 2000

 aagtattctg tactcttaga tggattctcc actcagttgc aacttggact 2050

 tgtcctcagc agctggtaat cttgctctgc ttgacaacat ctgagtgcag 2100

 ccgtttgaga agaaaacatc tattctctcc aaaaatgcac ccaactagct 2150

 ctatgtttac aaatggacat aggactcaaa gtttcagaga ccattgcaat 2200

 gaatccccaa taattgcaga actaaactca tttataaagc taaaataacc 2250

 ggatatatac atagcatgac atttctttgt gctttggctt acttgttt 2298

<210> 2293
<211> 512
<212> PRT
<213> Homo sapien

<400> 2293
 Met Gly Cys Ile Lys Ser Lys Gly Lys Asp Ser Leu Ser Asp Asp
   1               5                  10                  15

 Gly Val Asp Leu Lys Thr Gln Pro Val Arg Asn Thr Glu Arg Thr
                  20                  25                  30

 Ile Tyr Val Arg Asp Pro Thr Ser Asn Lys Gln Gln Arg Pro Val
                  35                  40                  45

 Pro Glu Ser Gln Leu Leu Pro Gly Gln Arg Phe Gln Thr Lys Asp
                  50                  55                  60

 Pro Glu Glu Gln Gly Asp Ile Val Val Ala Leu Tyr Pro Tyr Asp
                  65                  70                  75

 Gly Ile His Pro Asp Asp Leu Ser Phe Lys Lys Gly Glu Lys Met
                  80                  85                  90

 Lys Val Leu Glu Glu His Gly Glu Trp Trp Lys Ala Lys Ser Leu
                  95                 100                 105

 Leu Thr Lys Lys Glu Gly Phe Ile Pro Ser Asn Tyr Val Ala Lys
                 110                 115                 120

 Leu Asn Thr Leu Glu Thr Glu Glu Trp Phe Phe Lys Asp Ile Thr
                 125                 130                 135

 Arg Lys Asp Ala Glu Arg Gln Leu Leu Ala Pro Gly Asn Ser Ala
                 140                 145                 150

 Gly Ala Phe Leu Ile Arg Glu Ser Glu Thr Leu Lys Gly Ser Phe
                 155                 160                 165

 Ser Leu Ser Val Arg Asp Phe Asp Pro Val His Gly Asp Val Ile
                 170                 175                 180

 Lys His Tyr Lys Ile Arg Ser Leu Asp Asn Gly Gly Tyr Tyr Ile
                 185                 190                 195

 Ser Pro Arg Ile Thr Phe Pro Cys Ile Ser Asp Met Ile Lys His
                 200                 205                 210

 Tyr Gln Lys Gln Ala Asp Gly Leu Cys Arg Arg Leu Glu Lys Ala
                 215                 220                 225

 Cys Ile Ser Pro Lys Pro Gln Lys Pro Trp Asp Lys Asp Ala Trp
                 230                 235                 240

 Glu Ile Pro Arg Glu Ser Ile Lys Leu Val Lys Arg Leu Gly Ala
                 245                 250                 255

 Gly Gln Phe Gly Glu Val Trp Met Gly Tyr Tyr Asn Asn Ser Thr
                 260                 265                 270

 Lys Val Ala Val Lys Thr Leu Lys Pro Gly Thr Met Ser Val Gln
                 275                 280                 285

 Ala Phe Leu Glu Glu Ala Asn Leu Met Lys Thr Leu Gln His Asp
                 290                 295                 300

 Lys Leu Val Arg Leu Tyr Ala Val Val Thr Arg Glu Glu Pro Ile
                 305                 310                 315

 Tyr Ile Ile Thr Glu Tyr Met Ala Lys Gly Ser Leu Leu Asp Phe
                 320                 325                 330

 Leu Lys Ser Asp Glu Gly Gly Lys Val Leu Leu Pro Lys Leu Ile
                 335                 340                 345

 Asp Phe Ser Ala Gln Ile Ala Glu Gly Met Ala Tyr Ile Glu Arg
                 350                 355                 360

 Lys Asn Tyr Ile His Arg Asp Leu Arg Ala Ala Asn Val Leu Val
                 365                 370                 375

 Ser Glu Ser Leu Met Cys Lys Ile Ala Asp Phe Gly Leu Ala Arg
                 380                 385                 390

 Val Ile Glu Asp Asn Glu Tyr Thr Ala Arg Glu Gly Ala Lys Phe
                 395                 400                 405

 Pro Ile Lys Trp Thr Ala Pro Glu Ala Ile Asn Phe Gly Cys Phe
                 410                 415                 420

 Thr Ile Lys Ser Asp Val Trp Ser Phe Gly Ile Leu Leu Tyr Glu
                 425                 430                 435

 Ile Val Thr Tyr Gly Lys Ile Pro Tyr Pro Gly Arg Thr Asn Ala
                 440                 445                 450

 Asp Val Met Thr Ala Leu Ser Gln Gly Tyr Arg Met Pro Arg Val
                 455                 460                 465

 Glu Asn Cys Pro Asp Glu Leu Tyr Asp Ile Met Lys Met Cys Trp
                 470                 475                 480

 Lys Glu Lys Ala Glu Glu Arg Pro Thr Phe Asp Tyr Leu Gln Ser
                 485                 490                 495

 Val Leu Asp Asp Phe Tyr Thr Ala Thr Glu Gly Gln Tyr Gln Gln
                 500                 505                 510

 Gln Pro


<210> 2294
<211> 1061
<212> DNA
<213> Homo sapien

<400> 2294
 ccacaagctg gccccttggc ctcctagaga ccctgacatc tcctccagca 50

 gcatctgtcc tctctcctca gggaggcaag catttgatgc tcgaggtccc 100

 tggcagttgt ggtccttggc aagtgatgtg tgagtcccgt gtgtcatagg 150

 aagctcccca tccccatctg gtgaccaaag gcctggctac aagtagtgag 200

 tccttcctcc tccacccaga cctcactgct cagatcccct tcgccaactg 250

 ggacatcttc cgacatggcc tggatgctgt tgctcatctt gatcatggtc 300

 catccaggat cctgtgctct ctgggtgtcc cagccccctg agattcgtac 350

 cctggaagga tcctctgcct tcctgccctg ctccttcaat gccagccaag 400

 ggagactggc cattggctcc gtcacgtggt tccgagatga ggtggttcca 450

 gggaaggagg tgaggaatgg aaccccagag ttcaggggcc gcctggcccc 500

 acttgcttct tcccgtttcc tccatgacca ccaggctgag ctgcacatcc 550

 gggacgtgcg aggccatgac gccagcatct acgtgtgcag agtggaggtg 600

 ctgggccttg gtgtcgggac agggaatggg actcggctgg tggtggagaa 650

 agaacatcct cagctagggg ctggtacagt cctcctcctt cgggctggat 700

 tctatgctgt cagctttctc tctgtggccg tgggcagcac cgtctattac 750

 cagggcaaat gtctgacctg gaaaggtcca agaaggcagc tgccggctgt 800

 ggtcccagcg cccctcccac caccatgtgg gagctcagca catctgcttc 850

 ccccagtccc aggaggctga gcctgattgt cctgagaaat gggaaggatc 900

 agatatgact cctccttggc aactgccctt tcctgccagg cccacacata 950

 ccctcttctg gctgttaggg gagcttgggt ccctgaacac tgtcattcac 1000

 ccaataaatt actatttgac cccagagtgg gtggaagggt gaaaaaaaaa 1050

 aaaaaaaaaa a 1061

<210> 2295
<211> 201
<212> PRT
<213> Homo sapien

<400> 2295
 Met Ala Trp Met Leu Leu Leu Ile Leu Ile Met Val His Pro Gly
   1               5                  10                  15

 Ser Cys Ala Leu Trp Val Ser Gln Pro Pro Glu Ile Arg Thr Leu
                  20                  25                  30

 Glu Gly Ser Ser Ala Phe Leu Pro Cys Ser Phe Asn Ala Ser Gln
                  35                  40                  45

 Gly Arg Leu Ala Ile Gly Ser Val Thr Trp Phe Arg Asp Glu Val
                  50                  55                  60

 Val Pro Gly Lys Glu Val Arg Asn Gly Thr Pro Glu Phe Arg Gly
                  65                  70                  75

 Arg Leu Ala Pro Leu Ala Ser Ser Arg Phe Leu His Asp His Gln
                  80                  85                  90

 Ala Glu Leu His Ile Arg Asp Val Arg Gly His Asp Ala Ser Ile
                  95                 100                 105

 Tyr Val Cys Arg Val Glu Val Leu Gly Leu Gly Val Gly Thr Gly
                 110                 115                 120

 Asn Gly Thr Arg Leu Val Val Glu Lys Glu His Pro Gln Leu Gly
                 125                 130                 135

 Ala Gly Thr Val Leu Leu Leu Arg Ala Gly Phe Tyr Ala Val Ser
                 140                 145                 150

 Phe Leu Ser Val Ala Val Gly Ser Thr Val Tyr Tyr Gln Gly Lys
                 155                 160                 165

 Cys Leu Thr Trp Lys Gly Pro Arg Arg Gln Leu Pro Ala Val Val
                 170                 175                 180

 Pro Ala Pro Leu Pro Pro Pro Cys Gly Ser Ser Ala His Leu Leu
                 185                 190                 195

 Pro Pro Val Pro Gly Gly
                 200

<210> 2296
<211> 3579
<212> DNA
<213> Homo sapien

<400> 2296
 tcaggctcgc tgtcgcgcca ttttgccggg gtttgaatgt gaggcggagc 50

 ggcggcagga gcgggtagtg ccagctacgg tccgcggctg gggttccctc 100

 ctccgtttct gtatccccac gagatcctat agcaatggaa ctcagcgatg 150

 caaatctgca aacactaaca gaatatttaa agaaaacact tgatcctgat 200

 cctgccatcc gacgtccagc tgagaaattt cttgaatctg ttgaaggaaa 250

 tcagaattat ccactgttgc ttttgacatt actggagaag tcccaggata 300

 atgttatcaa agtatgtgct tcagtaacat tcaaaaacta tattaaaagg 350

 aactggagaa ttgttgaaga tgaaccaaac aaaatttgtg aagccgatcg 400

 agtggccatt aaagccaaca tagtgcactt gatgcttagc agcccagagc 450

 aaattcagaa gcagttaagt gatgcaatta gcattattgg cagagaagat 500

 tttccacaga aatggcctga cttgctgaca gaaatggtga atcgctttca 550

 gagtggagat ttccatgtta ttaatggagt cctccgtaca gcacattcat 600

 tatttaaaag ataccgtcat gaatttaagt caaacgagtt atggactgaa 650

 attaagcttg ttctggatgc ctttgctttg cctttgacta atctttttaa 700

 ggccactatt gaactctgca gtacccatgc aaatgatgcc tctgccctga 750

 ggattctgtt ttcttccctg atcctgatct caaaattgtt ctatagttta 800

 aactttcagg atctccctga attttttgaa gataatatgg aaacttggat 850

 gaataatttt catactctct taacattgga taataagctt ttacaaactg 900

 atgatgaaga ggaagccggc ttattggagc tcttaaaatc ccagatttgt 950

 gataatgccg cactctatgc acaaaagtac gatgaagaat tccagcgata 1000

 cctgcctcgt tttgttacag ccatctggaa tttactagtt acaacgggtc 1050

 aagaggttaa atatgatttg ttggtaagta atgcaattca atttctggct 1100

 tcagtttgtg agagacctca ttataagaat ctatttgagg accagaacac 1150

 gctgacaagt atctgtgaaa aggttattgt gcctaacatg gaatttagag 1200

 ctgctgatga agaagcattt gaagataatt ctgaggagta cataaggaga 1250

 gatttggaag gatctgatat tgatactaga cgcagggctg cttgtgatct 1300

 ggtacgagga ttatgcaagt tttttgaggg acctgtgaca ggaatcttct 1350

 ctggttatgt taattccatg ctgcaggaat acgcaaaaaa tccatctgtc 1400

 aactggaaac acaaagatgc agccatctac ctagtgacat ctttggcatc 1450

 aaaagcccaa acacagaagc atggaattac acaagcaaat gaacttgtaa 1500

 acctaactga gttctttgtg aatcacatcc tccctgattt aaaatcagct 1550

 aatgtgaatg aatttcctgt ccttaaagct gacggtatca aatatattat 1600

 gatttttaga aatcaagtgc caaaagaaca tcttttagtc tcgattcctc 1650

 tcttgattaa tcatcttcaa gctgaaagta ttgttgttca tacttacgca 1700

 gctcatgctc ttgaacggct ctttactatg cgagggccta acaatgccac 1750

 tctctttaca gctgcagaaa tcgcaccgtt tgttgagatt ctgctaacaa 1800

 accttttcaa agctctcaca cttcctggct cttcagaaaa tgaatatatt 1850

 atgaaagcta tcatgagaag tttttctctc ctacaagaag ccataatccc 1900

 ctacatccct actctcatca ctcagcttac acagaagcta ttagctgtta 1950

 gtaagaaccc aagcaaacct cactttaatc actacatgtt tgaagcaata 2000

 tgtttatcca taagaataac ttgcaaagct aaccctgctg ctgttgtaaa 2050

 ttttgaggag gctttgtttt tggtgtttac tgaaatctta caaaatgatg 2100

 tgcaagaatt tattccatac gtctttcaag tgatgtcttt gcttctggaa 2150

 acacacaaaa atgacatccc gtcttcctat atggccttat ttcctcatct 2200

 ccttcagcca gtgctttggg aaagaacagg aaatattcct gctctagtga 2250

 ggcttcttca agcattctta gaacgcggtt caaacacaat agcaagtgct 2300

 gcagctgaca aaattcctgg gttactaggt gtctttcaga agctgattgc 2350

 atccaaagca aatgaccacc aaggttttta tcttctaaac agtataatag 2400

 agcacatgcc tcctgaatca gttgaccaat ataggaaaca aatcttcatt 2450

 ctgctattcc agagacttca gaattccaaa acaaccaagt ttatcaagag 2500

 ttttttagtc tttattaatt tgtattgcat aaaatatggg gcactagcac 2550

 tacaagaaat atttgatggt atacaaccaa aaatgtttgg aatggttttg 2600

 gaaaaaatta ttattcctga aattcagaag gtatctggaa atgtagagaa 2650

 aaagatctgt gcggttggca taaccaaatt actaacagaa tgtcccccaa 2700

 tgatggacac tgagtatacc aaactgtgga ctccattatt acagtctttg 2750

 attggtcttt ttgagttacc cgaagatgat accattcctg atgaggaaca 2800

 ttttattgac atagaagata caccaggata tcagactgcc ttctcacagt 2850

 tggcatttgc tgggaaaaaa gagcatgatc ctgtaggtca aatggtgaat 2900

 aaccccaaaa ttcacctggc acagtcactt cacaagttgt ctaccgcctg 2950

 tccaggaagg gttccatcaa tggtgagcac cagcctgaat gcagaagcgc 3000

 tccagtatct ccaagggtac cttcaggcag ccagtgtgac actgctttaa 3050

 actgcatttt tctaatgggc taaacccaga tggtttccta ggaaatcaca 3100

 ggcttctgag cacagctgca ttaaaacaaa ggaagttctc cttttgaact 3150

 tgtcacgaat tccatcttgt aaaggatatt aaatgttgct ttaacctgaa 3200

 ccttgagcaa attagttggt ttgtgtgatc atacagttat gtgggtggct 3250

 tctagtttgc aacttcaagg gacaagtatt aatagttcag tgtatggcgt 3300

 tggtttgtgt tgagcgtttg cacggtttgg ataatcttaa attttgacgg 3350

 acactgtgga gactttctgt tactaaatcc ttttgttttg aagctgttgc 3400

 tatttgtatt tctcttgtcc tttatatttt ttgtctgttt atttacgctt 3450

 ttattggaaa tgtgaataag taaagaatta cttgtgttac ttgccaagca 3500

 gtgcacattt catagtttca aatctgtaat cagcaataaa aatcctaaaa 3550

 tatgtaccta aaaaaaaaaa aaaaaaaaa 3579

<210> 2297
<211> 971
<212> PRT
<213> Homo sapien

<400> 2297
 Met Glu Leu Ser Asp Ala Asn Leu Gln Thr Leu Thr Glu Tyr Leu
   1               5                  10                  15

 Lys Lys Thr Leu Asp Pro Asp Pro Ala Ile Arg Arg Pro Ala Glu
                  20                  25                  30

 Lys Phe Leu Glu Ser Val Glu Gly Asn Gln Asn Tyr Pro Leu Leu
                  35                  40                  45

 Leu Leu Thr Leu Leu Glu Lys Ser Gln Asp Asn Val Ile Lys Val
                  50                  55                  60

 Cys Ala Ser Val Thr Phe Lys Asn Tyr Ile Lys Arg Asn Trp Arg
                  65                  70                  75

 Ile Val Glu Asp Glu Pro Asn Lys Ile Cys Glu Ala Asp Arg Val
                  80                  85                  90

 Ala Ile Lys Ala Asn Ile Val His Leu Met Leu Ser Ser Pro Glu
                  95                 100                 105

 Gln Ile Gln Lys Gln Leu Ser Asp Ala Ile Ser Ile Ile Gly Arg
                 110                 115                 120

 Glu Asp Phe Pro Gln Lys Trp Pro Asp Leu Leu Thr Glu Met Val
                 125                 130                 135

 Asn Arg Phe Gln Ser Gly Asp Phe His Val Ile Asn Gly Val Leu
                 140                 145                 150

 Arg Thr Ala His Ser Leu Phe Lys Arg Tyr Arg His Glu Phe Lys
                 155                 160                 165

 Ser Asn Glu Leu Trp Thr Glu Ile Lys Leu Val Leu Asp Ala Phe
                 170                 175                 180

 Ala Leu Pro Leu Thr Asn Leu Phe Lys Ala Thr Ile Glu Leu Cys
                 185                 190                 195

 Ser Thr His Ala Asn Asp Ala Ser Ala Leu Arg Ile Leu Phe Ser
                 200                 205                 210

 Ser Leu Ile Leu Ile Ser Lys Leu Phe Tyr Ser Leu Asn Phe Gln
                 215                 220                 225

 Asp Leu Pro Glu Phe Phe Glu Asp Asn Met Glu Thr Trp Met Asn
                 230                 235                 240

 Asn Phe His Thr Leu Leu Thr Leu Asp Asn Lys Leu Leu Gln Thr
                 245                 250                 255

 Asp Asp Glu Glu Glu Ala Gly Leu Leu Glu Leu Leu Lys Ser Gln
                 260                 265                 270

 Ile Cys Asp Asn Ala Ala Leu Tyr Ala Gln Lys Tyr Asp Glu Glu
                 275                 280                 285

 Phe Gln Arg Tyr Leu Pro Arg Phe Val Thr Ala Ile Trp Asn Leu
                 290                 295                 300

 Leu Val Thr Thr Gly Gln Glu Val Lys Tyr Asp Leu Leu Val Ser
                 305                 310                 315

 Asn Ala Ile Gln Phe Leu Ala Ser Val Cys Glu Arg Pro His Tyr
                 320                 325                 330

 Lys Asn Leu Phe Glu Asp Gln Asn Thr Leu Thr Ser Ile Cys Glu
                 335                 340                 345

 Lys Val Ile Val Pro Asn Met Glu Phe Arg Ala Ala Asp Glu Glu
                 350                 355                 360

 Ala Phe Glu Asp Asn Ser Glu Glu Tyr Ile Arg Arg Asp Leu Glu
                 365                 370                 375

 Gly Ser Asp Ile Asp Thr Arg Arg Arg Ala Ala Cys Asp Leu Val
                 380                 385                 390

 Arg Gly Leu Cys Lys Phe Phe Glu Gly Pro Val Thr Gly Ile Phe
                 395                 400                 405

 Ser Gly Tyr Val Asn Ser Met Leu Gln Glu Tyr Ala Lys Asn Pro
                 410                 415                 420

 Ser Val Asn Trp Lys His Lys Asp Ala Ala Ile Tyr Leu Val Thr
                 425                 430                 435

 Ser Leu Ala Ser Lys Ala Gln Thr Gln Lys His Gly Ile Thr Gln
                 440                 445                 450

 Ala Asn Glu Leu Val Asn Leu Thr Glu Phe Phe Val Asn His Ile
                 455                 460                 465

 Leu Pro Asp Leu Lys Ser Ala Asn Val Asn Glu Phe Pro Val Leu
                 470                 475                 480

 Lys Ala Asp Gly Ile Lys Tyr Ile Met Ile Phe Arg Asn Gln Val
                 485                 490                 495

 Pro Lys Glu His Leu Leu Val Ser Ile Pro Leu Leu Ile Asn His
                 500                 505                 510

 Leu Gln Ala Glu Ser Ile Val Val His Thr Tyr Ala Ala His Ala
                 515                 520                 525

 Leu Glu Arg Leu Phe Thr Met Arg Gly Pro Asn Asn Ala Thr Leu
                 530                 535                 540

 Phe Thr Ala Ala Glu Ile Ala Pro Phe Val Glu Ile Leu Leu Thr
                 545                 550                 555

 Asn Leu Phe Lys Ala Leu Thr Leu Pro Gly Ser Ser Glu Asn Glu
                 560                 565                 570

 Tyr Ile Met Lys Ala Ile Met Arg Ser Phe Ser Leu Leu Gln Glu
                 575                 580                 585

 Ala Ile Ile Pro Tyr Ile Pro Thr Leu Ile Thr Gln Leu Thr Gln
                 590                 595                 600

 Lys Leu Leu Ala Val Ser Lys Asn Pro Ser Lys Pro His Phe Asn
                 605                 610                 615

 His Tyr Met Phe Glu Ala Ile Cys Leu Ser Ile Arg Ile Thr Cys
                 620                 625                 630

 Lys Ala Asn Pro Ala Ala Val Val Asn Phe Glu Glu Ala Leu Phe
                 635                 640                 645

 Leu Val Phe Thr Glu Ile Leu Gln Asn Asp Val Gln Glu Phe Ile
                 650                 655                 660

 Pro Tyr Val Phe Gln Val Met Ser Leu Leu Leu Glu Thr His Lys
                 665                 670                 675

 Asn Asp Ile Pro Ser Ser Tyr Met Ala Leu Phe Pro His Leu Leu
                 680                 685                 690

 Gln Pro Val Leu Trp Glu Arg Thr Gly Asn Ile Pro Ala Leu Val
                 695                 700                 705

 Arg Leu Leu Gln Ala Phe Leu Glu Arg Gly Ser Asn Thr Ile Ala
                 710                 715                 720

 Ser Ala Ala Ala Asp Lys Ile Pro Gly Leu Leu Gly Val Phe Gln
                 725                 730                 735

 Lys Leu Ile Ala Ser Lys Ala Asn Asp His Gln Gly Phe Tyr Leu
                 740                 745                 750

 Leu Asn Ser Ile Ile Glu His Met Pro Pro Glu Ser Val Asp Gln
                 755                 760                 765

 Tyr Arg Lys Gln Ile Phe Ile Leu Leu Phe Gln Arg Leu Gln Asn
                 770                 775                 780

 Ser Lys Thr Thr Lys Phe Ile Lys Ser Phe Leu Val Phe Ile Asn
                 785                 790                 795

 Leu Tyr Cys Ile Lys Tyr Gly Ala Leu Ala Leu Gln Glu Ile Phe
                 800                 805                 810

 Asp Gly Ile Gln Pro Lys Met Phe Gly Met Val Leu Glu Lys Ile
                 815                 820                 825

 Ile Ile Pro Glu Ile Gln Lys Val Ser Gly Asn Val Glu Lys Lys
                 830                 835                 840

 Ile Cys Ala Val Gly Ile Thr Lys Leu Leu Thr Glu Cys Pro Pro
                 845                 850                 855

 Met Met Asp Thr Glu Tyr Thr Lys Leu Trp Thr Pro Leu Leu Gln
                 860                 865                 870

 Ser Leu Ile Gly Leu Phe Glu Leu Pro Glu Asp Asp Thr Ile Pro
                 875                 880                 885

 Asp Glu Glu His Phe Ile Asp Ile Glu Asp Thr Pro Gly Tyr Gln
                 890                 895                 900

 Thr Ala Phe Ser Gln Leu Ala Phe Ala Gly Lys Lys Glu His Asp
                 905                 910                 915

 Pro Val Gly Gln Met Val Asn Asn Pro Lys Ile His Leu Ala Gln
                 920                 925                 930

 Ser Leu His Lys Leu Ser Thr Ala Cys Pro Gly Arg Val Pro Ser
                 935                 940                 945

 Met Val Ser Thr Ser Leu Asn Ala Glu Ala Leu Gln Tyr Leu Gln
                 950                 955                 960

 Gly Tyr Leu Gln Ala Ala Ser Val Thr Leu Leu
                 965                 970

<210> 2298
<211> 3433
<212> DNA
<213> Homo sapien

<400> 2298
 gtcctcctcc tagccggact ggagggagac aaagcagcgc ccgtctgctt 50

 cgggcctctg gaatttagcg ctcgcccagc tagccgcaga aatgactgct 100

 gtccatgcag gcaacataaa cttcaagtgg gatcctaaaa gtctagagat 150

 caggactctg gcagttgaga gactgttgga gcctcttgtt acacaggtta 200

 caacccttgt aaacaccaat agtaaagggc cctctaataa gaagagaggt 250

 cgttctaaga aggcccatgt tttggctgca tctgttgaac aagcaactga 300

 gaatttcttg gagaaggggg ataaaattgc gaaggagagc cagtttctca 350

 aggaggagct tgtggctgct gtagaagatg ttcgaaaaca aggtgatttg 400

 atgaaggctg ctgcaggaga gttcgcagat gatccctgct cttctgtgaa 450

 gcgaggcaac atggttcggg cagctcgagc tttgctctct gctgttaccc 500

 ggttgctgat tttggctgac atggcagatg tctacaaatt acttgttcag 550

 ctgaaagttg tggaagatgg tatcttgaag ttgaggaatg ctggcaatga 600

 acaagactta ggaatccagt ataaagccct aaaacctgaa gtggataagc 650

 tgaacattat ggcagccaaa agacaacagg aattgaaaga tgttggccat 700

 cgtgatcaga tggctgcagc tagaggaatc ctgcagaaga acgttccgat 750

 cctctatact gcatcccagg catgcctaca gcaccctgat gtcgcagcct 800

 ataaggccaa ccgggacctg atatacaagc agctgcagca ggcggtcaca 850

 ggcatttcca atgcagccca ggccactgcc tcagacgatg cctcacagca 900

 ccagggtgga ggaggaggag aactggcata tgcactcaat aactttgaca 950

 aacaaatcat tgtggacccc ttgagcttca gcgaggagcg ctttaggcct 1000

 tccctggagg agcgtctgga aagcatcatt agtggggctg ccttgatggc 1050

 cgactcctcc tgcacgcgtg atgaccgtcg tgagcgaatt gtggcagagt 1100

 gtaatgctgt ccgcaaggcc ctgcaggacc tgctttcgga gtacatgggc 1150

 aatgctggac gtaaagaaag aagtgatgca ctcaattctg caatagataa 1200

 aatgaccaag aagaccaggg acttgcgtag acagctccgc aaagctgtca 1250

 tggaccacgt ttcagattct ttcctggaaa ccaatgttcc acttttggta 1300

 ttgattgaag ctgcaaagaa tggaaatgag aaagaagtta aggagtatgc 1350

 ccaagttttc cgtgaacatg ccaacaaatt gattgaggtt gccaacttgg 1400

 cctgttccat ctcaaataat gaagaaggtg taaagcttgt tcgaatgtct 1450

 gcaagccagt tagaagccct ctgtcctcag gttattaatg ctgcactggc 1500

 tttagcagca aaaccacaga gtaaactggc ccaagagaac atggatcttt 1550

 ttaaagaaca atgggaaaaa caagtccgtg ttctcacaga tgctgtcgat 1600

 gacattactt ccattgatga cttcttggct gtctcagaga atcacatttt 1650

 ggaagatgtg aacaaatgtg tcattgctct ccaagagaag gatgtggatg 1700

 gcctggaccg cacagctggt gcaattcgag gccgggcagc ccgggtcatt 1750

 cacgtagtca cctcagagat ggacaactat gagccaggag tctacacaga 1800

 gaaggttctg gaagccacta agctgctctc caacacagtc atgccacgtt 1850

 ttactgagca agtagaagca gccgtggaag ccctcagctc ggaccctgcc 1900

 cagcccatgg atgagaatga gtttatcgat gcttcccgcc tggtatatga 1950

 tggcatccgg gacatcagga aagcagtgct gatgataagg acccctgagg 2000

 agttggatga ctctgacttt gagacagaag attttgatgt cagaagcagg 2050

 acgagcgtcc agacagaaga cgatcagctg atagctggcc agagtgcccg 2100

 ggcgatcatg gctcagcttc cccaggagca aaaagcgaag attgcggaac 2150

 aggtggccag cttccaggaa gaaaagagca agctggatgc tgaagtgtcc 2200

 aaatgggacg acagtggcaa tgacatcatt gtgctggcca agcagatgtg 2250

 catgattatg atggagatga cagactttac ccgaggtaaa ggaccactca 2300

 aaaatacatc ggatgtcatc agtgctgcca agaaaattgc tgaggcagga 2350

 tccaggatgg acaagcttgg ccgcaccatt gcagaccatt gccccgactc 2400

 ggcttgcaag caggacctgc tggcctacct gcaacgcatc gccctctact 2450

 gccaccatct gaacatctgc agcaaggtca aggccgaggt gcagaatctc 2500

 ggcggggagc ttgttgtctc tggggtggac agcgccatgt ccctgatcca 2550

 ggcagccaag aacttgatga atgctgtggt gcagacagtg aaggcatcct 2600

 acgtcgcctc taccaaatac caaaagtcac agggtatggc ttccctcaac 2650

 cttcctgctg tgtcatggaa gatgaaggca ccagagaaaa agccattggt 2700

 gaagagagag aaacaggatg agacacagac caagattaaa cgggcatctc 2750

 agaagaagca cgtgaacccg gtgcaggccc tcagcgagtt caaagctatg 2800

 gacagcatct aagtctgccc aggccggccg cccccacccc tcggggctcc 2850

 tgaatatcag tcactgttcg tcactcaaat gaatttgcta aatacaacac 2900

 tgatactaga ttccacaggg aaatgggcag actgaaccag tccaggtggt 2950

 gaattttcca agaacatagt ttaagttgat taaaaatgct tttagaatgc 3000

 aggagcctac ttctagctgt attttttgta tgcttaaata aaaataaaat 3050

 tcataaccaa agagaatccc acattagctt gttagtaagc tctgaccaag 3100

 ccgagatgcc cattctctta gtgatggcgg cgttagggtt tgagagaagg 3150

 gaatttggct caacttcagt tgagagggtg cagtccagac agcttgactg 3200

 cttttaaatg accaaagatg acctgtggta agcaacctgg gcatcttagg 3250

 aagcagtccc tggagaaggc atgttcccca gaaaggtctc tggagggaca 3300

 aactcactca gtaaaacata atgtatcatg aagaaaactg attctctatg 3350

 acatgaaatg aaaattttaa tgcattgtta taattactaa tgtaccgctg 3400

 ctgcaggaca ttaataaagt tgctttttta ggc 3433

<210> 2299
<211> 906
<212> PRT
<213> Homo sapien

<400> 2299
 Met Thr Ala Val His Ala Gly Asn Ile Asn Phe Lys Trp Asp Pro
   1               5                  10                  15

 Lys Ser Leu Glu Ile Arg Thr Leu Ala Val Glu Arg Leu Leu Glu
                  20                  25                  30

 Pro Leu Val Thr Gln Val Thr Thr Leu Val Asn Thr Asn Ser Lys
                  35                  40                  45

 Gly Pro Ser Asn Lys Lys Arg Gly Arg Ser Lys Lys Ala His Val
                  50                  55                  60

 Leu Ala Ala Ser Val Glu Gln Ala Thr Glu Asn Phe Leu Glu Lys
                  65                  70                  75

 Gly Asp Lys Ile Ala Lys Glu Ser Gln Phe Leu Lys Glu Glu Leu
                  80                  85                  90

 Val Ala Ala Val Glu Asp Val Arg Lys Gln Gly Asp Leu Met Lys
                  95                 100                 105

 Ala Ala Ala Gly Glu Phe Ala Asp Asp Pro Cys Ser Ser Val Lys
                 110                 115                 120

 Arg Gly Asn Met Val Arg Ala Ala Arg Ala Leu Leu Ser Ala Val
                 125                 130                 135

 Thr Arg Leu Leu Ile Leu Ala Asp Met Ala Asp Val Tyr Lys Leu
                 140                 145                 150

 Leu Val Gln Leu Lys Val Val Glu Asp Gly Ile Leu Lys Leu Arg
                 155                 160                 165

 Asn Ala Gly Asn Glu Gln Asp Leu Gly Ile Gln Tyr Lys Ala Leu
                 170                 175                 180

 Lys Pro Glu Val Asp Lys Leu Asn Ile Met Ala Ala Lys Arg Gln
                 185                 190                 195

 Gln Glu Leu Lys Asp Val Gly His Arg Asp Gln Met Ala Ala Ala
                 200                 205                 210

 Arg Gly Ile Leu Gln Lys Asn Val Pro Ile Leu Tyr Thr Ala Ser
                 215                 220                 225

 Gln Ala Cys Leu Gln His Pro Asp Val Ala Ala Tyr Lys Ala Asn
                 230                 235                 240

 Arg Asp Leu Ile Tyr Lys Gln Leu Gln Gln Ala Val Thr Gly Ile
                 245                 250                 255

 Ser Asn Ala Ala Gln Ala Thr Ala Ser Asp Asp Ala Ser Gln His
                 260                 265                 270

 Gln Gly Gly Gly Gly Gly Glu Leu Ala Tyr Ala Leu Asn Asn Phe
                 275                 280                 285

 Asp Lys Gln Ile Ile Val Asp Pro Leu Ser Phe Ser Glu Glu Arg
                 290                 295                 300

 Phe Arg Pro Ser Leu Glu Glu Arg Leu Glu Ser Ile Ile Ser Gly
                 305                 310                 315

 Ala Ala Leu Met Ala Asp Ser Ser Cys Thr Arg Asp Asp Arg Arg
                 320                 325                 330

 Glu Arg Ile Val Ala Glu Cys Asn Ala Val Arg Lys Ala Leu Gln
                 335                 340                 345

 Asp Leu Leu Ser Glu Tyr Met Gly Asn Ala Gly Arg Lys Glu Arg
                 350                 355                 360

 Ser Asp Ala Leu Asn Ser Ala Ile Asp Lys Met Thr Lys Lys Thr
                 365                 370                 375

 Arg Asp Leu Arg Arg Gln Leu Arg Lys Ala Val Met Asp His Val
                 380                 385                 390

 Ser Asp Ser Phe Leu Glu Thr Asn Val Pro Leu Leu Val Leu Ile
                 395                 400                 405

 Glu Ala Ala Lys Asn Gly Asn Glu Lys Glu Val Lys Glu Tyr Ala
                 410                 415                 420

 Gln Val Phe Arg Glu His Ala Asn Lys Leu Ile Glu Val Ala Asn
                 425                 430                 435

 Leu Ala Cys Ser Ile Ser Asn Asn Glu Glu Gly Val Lys Leu Val
                 440                 445                 450

 Arg Met Ser Ala Ser Gln Leu Glu Ala Leu Cys Pro Gln Val Ile
                 455                 460                 465

 Asn Ala Ala Leu Ala Leu Ala Ala Lys Pro Gln Ser Lys Leu Ala
                 470                 475                 480

 Gln Glu Asn Met Asp Leu Phe Lys Glu Gln Trp Glu Lys Gln Val
                 485                 490                 495

 Arg Val Leu Thr Asp Ala Val Asp Asp Ile Thr Ser Ile Asp Asp
                 500                 505                 510

 Phe Leu Ala Val Ser Glu Asn His Ile Leu Glu Asp Val Asn Lys
                 515                 520                 525

 Cys Val Ile Ala Leu Gln Glu Lys Asp Val Asp Gly Leu Asp Arg
                 530                 535                 540

 Thr Ala Gly Ala Ile Arg Gly Arg Ala Ala Arg Val Ile His Val
                 545                 550                 555

 Val Thr Ser Glu Met Asp Asn Tyr Glu Pro Gly Val Tyr Thr Glu
                 560                 565                 570

 Lys Val Leu Glu Ala Thr Lys Leu Leu Ser Asn Thr Val Met Pro
                 575                 580                 585

 Arg Phe Thr Glu Gln Val Glu Ala Ala Val Glu Ala Leu Ser Ser
                 590                 595                 600

 Asp Pro Ala Gln Pro Met Asp Glu Asn Glu Phe Ile Asp Ala Ser
                 605                 610                 615

 Arg Leu Val Tyr Asp Gly Ile Arg Asp Ile Arg Lys Ala Val Leu
                 620                 625                 630

 Met Ile Arg Thr Pro Glu Glu Leu Asp Asp Ser Asp Phe Glu Thr
                 635                 640                 645

 Glu Asp Phe Asp Val Arg Ser Arg Thr Ser Val Gln Thr Glu Asp
                 650                 655                 660

 Asp Gln Leu Ile Ala Gly Gln Ser Ala Arg Ala Ile Met Ala Gln
                 665                 670                 675

 Leu Pro Gln Glu Gln Lys Ala Lys Ile Ala Glu Gln Val Ala Ser
                 680                 685                 690

 Phe Gln Glu Glu Lys Ser Lys Leu Asp Ala Glu Val Ser Lys Trp
                 695                 700                 705

 Asp Asp Ser Gly Asn Asp Ile Ile Val Leu Ala Lys Gln Met Cys
                 710                 715                 720

 Met Ile Met Met Glu Met Thr Asp Phe Thr Arg Gly Lys Gly Pro
                 725                 730                 735

 Leu Lys Asn Thr Ser Asp Val Ile Ser Ala Ala Lys Lys Ile Ala
                 740                 745                 750

 Glu Ala Gly Ser Arg Met Asp Lys Leu Gly Arg Thr Ile Ala Asp
                 755                 760                 765

 His Cys Pro Asp Ser Ala Cys Lys Gln Asp Leu Leu Ala Tyr Leu
                 770                 775                 780

 Gln Arg Ile Ala Leu Tyr Cys His His Leu Asn Ile Cys Ser Lys
                 785                 790                 795

 Val Lys Ala Glu Val Gln Asn Leu Gly Gly Glu Leu Val Val Ser
                 800                 805                 810

 Gly Val Asp Ser Ala Met Ser Leu Ile Gln Ala Ala Lys Asn Leu
                 815                 820                 825

 Met Asn Ala Val Val Gln Thr Val Lys Ala Ser Tyr Val Ala Ser
                 830                 835                 840

 Thr Lys Tyr Gln Lys Ser Gln Gly Met Ala Ser Leu Asn Leu Pro
                 845                 850                 855

 Ala Val Ser Trp Lys Met Lys Ala Pro Glu Lys Lys Pro Leu Val
                 860                 865                 870

 Lys Arg Glu Lys Gln Asp Glu Thr Gln Thr Lys Ile Lys Arg Ala
                 875                 880                 885

 Ser Gln Lys Lys His Val Asn Pro Val Gln Ala Leu Ser Glu Phe
                 890                 895                 900

 Lys Ala Met Asp Ser Ile
                 905

<210> 2300
<211> 1743
<212> DNA
<213> Homo sapien

<400> 2300
 ctgaaggcgg aaccacgacg ggcagagagc acggagccgg gaagcccctg 50

 ggcgcccgtc ggagggctat ggagcagcgg ccgcggggct gcgcggcggt 100

 ggcggcggcg ctcctcctgg tgctgctggg ggcccgggcc cagggcggca 150

 ctcgtagccc caggtgtgac tgtgccggtg acttccacaa gaagattggt 200

 ctgttttgtt gcagaggctg cccagcgggg cactacctga aggccccttg 250

 cacggagccc tgcggcaact ccacctgcct tgtgtgtccc caagacacct 300

 tcttggcctg ggagaaccac cataattctg aatgtgcccg ctgccaggcc 350

 tgtgatgagc aggcctccca ggtggcgctg gagaactgtt cagcagtggc 400

 cgacacccgc tgtggctgta agccaggctg gtttgtggag tgccaggtca 450

 gccaatgtgt cagcagttca cccttctact gccaaccatg cctagactgc 500

 ggggccctgc accgccacac acggctactc tgttcccgca gagatactga 550

 ctgtgggacc tgcctgcctg gcttctatga acatggcgat ggctgcgtgt 600

 cctgccccac gagcaccctg gggagctgtc cagagcgctg tgccgctgtc 650

 tgtggctgga ggcagagtag gtggtgtgct gggaatgcgc gtgggagaac 700

 tgggatggac cgaggggagg cgggtgagga ggggggcaac cacccaacac 750

 ccaccagctg ctttcagtgt tctgggtcca ggtgctcctg gctggccttg 800

 tggtccccct cctgcttggg gccaccctga cctacacata ccgccactgc 850

 tggcctcaca agcccctggt tactgcagat gaagctggga tggaggctct 900

 gaccccacca ccggccaccc atctgtcacc cttggacagc gcccacaccc 950

 ttctagcacc tcctgacagc agtgagaaga tctgcaccgt ccagttggtg 1000

 ggtaacagct ggacccctgg ctaccccgag acccaggagg cgctctgccc 1050

 gcaggtgaca tggtcctggg accagttgcc cagcagagct cttggccccg 1100

 ctcgtgcgcc cacactctcg ccagagtccc cagccggctc gccagccatg 1150

 atgctgcagc cgggcccgca gctctacgac gtgatggacg cggtcccagc 1200

 gcggcgctgg aaggagttcg tgcgcacgct ggggctgcgc gaggcagaga 1250

 tcgaagccgt ggaggtggag atcggtctct tccgagacca gcagtacgag 1300

 atgctcaagc actggcgcca gcagcagccc gcgggcctcg gagccgttta 1350

 cgcggccctg gagcgcatgg ggctggacgg ctgcgtggaa gacttgcgca 1400

 gccgcctgca gcgtggcccg tgacacgcag cccacttgcc acctaggcgc 1450

 tctggtggcc cttgcagaag ccctaagtac ggttacttat gcgtgtagac 1500

 attttatgtc acttattaag ccgctggcac ggccctgcgt aggcacacca 1550

 gccggcccca cccctgctcg cccctatcgc tccagccaag gcgaagaagc 1600

 acgaacgaat gtcgagaggg ggtgaagaca tttctcaact tctcggccgg 1650

 agtttggctg agatcgcggt attaaatctg tgaaagaaat aaagaaaaaa 1700

 acaaaacaaa acaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1743

<210> 2301
<211> 9886
<212> DNA
<213> Homo sapien

<400> 2301
 gcgagaggag tcgggatctg cgctgcagcc accgccgcgg ttgatactac 50

 tttgaccttc cgagtgcagt gaggcataca tcacaatttg gaattatgca 100

 ttggtttatc aatttacttg tttattgtca ccctgctgcc cagatatgac 150

 ttcatgagga cagtgatgtg tgttctgaaa ttgtgaacca tgagtctagt 200

 acttaatgat ctgcttatct gctgccgtca actagaacat gatagagcta 250

 cagaacgaaa gaaagaagtt gagaaattta agcgcctgat tcgagatcct 300

 gaaacaatta aacatctaga tcggcattca gattccaaac aaggaaaata 350

 tttgaattgg gatgctgttt ttagattttt acagaaatat attcagaaag 400

 aaacagaatg tctgagaata gcaaaaccaa atgtatcagc ctcaacacaa 450

 gcctccaggc agaaaaagat gcaggaaatc agtagtttgg tcaaatactt 500

 catcaaatgt gcaaacagaa gagcacctag gctaaaatgt caagaactct 550

 taaattatat catggataca gtgaaagatt catctaatgg tgctatttac 600

 ggagctgatt gtagcaacat actactcaaa gacattcttt ctgtgagaaa 650

 atactggtgt gaaatatctc agcaacagtg gttagaattg ttctctgtgt 700

 acttcaggct ctatctgaaa ccttcacaag atgttcatag agttttagtg 750

 gctagaataa ttcatgctgt taccaaagga tgctgttctc agactgacgg 800

 attaaattcc aaatttttgg actttttttc caaggctatt cagtgtgcga 850

 gacaagaaaa gagctcttca ggtctaaatc atatcttagc agctcttact 900

 atcttcctca agactttggc tgtcaacttt cgaattcgag tgtgtgaatt 950

 aggagatgaa attcttccca ctttgcttta tatttggact caacataggc 1000

 ttaatgattc tttaaaagaa gtcattattg aattatttca actgcaaatt 1050

 tatatccatc atccgaaagg agccaaaacc caagaaaaag gtgcttatga 1100

 atcaacaaaa tggagaagta ttttatacaa cttatatgat ctgctagtga 1150

 atgagataag tcatatagga agtagaggaa agtattcttc aggatttcgt 1200

 aatattgccg tcaaagaaaa tttgattgaa ttgatggcag atatctgtca 1250

 ccaggttttt aatgaagata ccagatcctt ggagatttct caatcttaca 1300

 ctactacaca aagagaatct agtgattaca gtgtcccttg caaaaggaag 1350

 aaaatagaac taggctggga agtaataaaa gatcaccttc agaagtcaca 1400

 gaatgatttt gatcttgtgc cttggctaca gattgcaacc caattaatat 1450

 caaagtatcc tgcaagttta cctaactgtg agctgtctcc attactgatg 1500

 atactatctc agcttctacc ccaacagcga catggggaac gtacaccata 1550

 tgtgttacga tgccttacgg aagttgcatt gtgtcaagac aagaggtcaa 1600

 acctagaaag ctcacaaaag tcagatttat taaaactctg gaataaaatt 1650

 tggtgtatta cctttcgtgg tataagttct gagcaaatac aagctgaaaa 1700

 ctttggctta cttggagcca taattcaggg tagtttagtt gaggttgaca 1750

 gagaattctg gaagttattt actgggtcag cctgcagacc ttcatgtcct 1800

 gcagtatgct gtttgacttt ggcactgacc accagtatag ttccaggagc 1850

 ggtaaaaatg ggaatagagc aaaatatgtg tgaagtaaat agaagctttt 1900

 ctttaaagga atcaataatg aaatggctct tattctatca gttagagggt 1950

 gacttagaaa atagcacaga agtgcctcca attcttcaca gtaattttcc 2000

 tcatcttgta ctggagaaaa ttcttgtgag tctcactatg aaaaactgta 2050

 aagctgcaat gaattttttc caaagcgtgc cagaatgtga acaccaccaa 2100

 aaagataaag aagaactttc attctcagaa gtagaagaac tatttcttca 2150

 gacaactttt gacaagatgg actttttaac cattgtgaga gaatgtggta 2200

 tagaaaagca ccagtccagt attggcttct ctgtccacca gaatctcaag 2250

 gaatcactgg atcgctgtct tctgggatta tcagaacagc ttctgaataa 2300

 ttactcatct gagattacaa attcagaaac tcttgtccgg tgttcacgtc 2350

 ttttggtggg tgtccttggc tgctactgtt acatgggtgt aatagctgaa 2400

 gaggaagcat ataagtcaga attattccag aaagccaact ctctaatgca 2450

 atgtgcagga gaaagtatca ctctgtttaa aaataagaca aatgaggaat 2500

 tcagaattgg ttccttgaga aatatgatgc agctatgtac acgttgcttg 2550

 agcaactgta ccaagaagag tccaaataag attgcatctg gctttttcct 2600

 gcgattgtta acatcaaagc taatgaatga cattgcagat atttgtaaaa 2650

 gtttagcatc cttcatcaaa aagccatttg accgtggaga agtagaatca 2700

 atggaagatg atactaatgg aaatctaatg gaggtggagg atcagtcatc 2750

 catgaatcta tttaacgatt accctgatag tagtgttagt gatgcaaacg 2800

 aacctggaga gagccaaagt accataggtg ccattaatcc tttagctgaa 2850

 gaatatctgt caaagcaaga tctacttttc ttagacatgc tcaagttctt 2900

 gtgtttgtgt gtaactactg ctcagaccaa tactgtgtcc tttagggcag 2950

 ctgatattcg gaggaaattg ttaatgttaa ttgattctag cacgctagaa 3000

 cctaccaaat ccctccacct gcatatgtat ctaatgcttt taaaggagct 3050

 tcctggagaa gagtacccct tgccaatgga agatgttctt gaacttctga 3100

 aaccactatc caatgtgtgt tctttgtatc gtcgtgacca agatgtttgt 3150

 aaaactattt taaaccatgt ccttcatgta gtgaaaaacc taggtcaaag 3200

 caatatggac tctgagaaca caagggatgc tcaaggacag tttcttacag 3250

 taattggagc attttggcat ctaacaaagg agaggaaata tatattctct 3300

 gtaagaatgg ccctagtaaa ttgccttaaa actttgcttg aggctgatcc 3350

 ttattcaaaa tgggccattc ttaatgtaat gggaaaagac tttcctgtaa 3400

 atgaagtatt tacacaattt cttgctgaca atcatcacca agttcgcatg 3450

 ttggctgcag agtcaatcaa tagattgttc caggacacga agggagattc 3500

 ttccaggtta ctgaaagcac ttcctttgaa gcttcagcaa acagcttttg 3550

 aaaatgcata cttgaaagct caggaaggaa tgagagaaat gtcccatagt 3600

 gctgagaacc ctgaaacttt ggatgaaatt tataatagaa aatctgtttt 3650

 actgacgttg atagctgtgg ttttatcctg tagccctatc tgcgaaaaac 3700

 aggctttgtt tgccctgtgt aaatctgtga aagagaatgg attagaacct 3750

 caccttgtga aaaaggtttt agagaaagtt tctgaaactt ttggatatag 3800

 acgtttagaa gactttatgg catctcattt agattatctg gttttggaat 3850

 ggctaaatct tcaagatact gaatacaact tatcttcttt tccttttatt 3900

 ttattaaact acacaaatat tgaggatttc tatagatctt gttataaggt 3950

 tttgattcca catctggtga ttagaagtca ttttgatgag gtgaagtcca 4000

 ttgctaatca gattcaagag gactggaaaa gtcttctaac agactgcttt 4050

 ccaaagattc ttgtaaatat tcttccttat tttgcctatg agggtaccag 4100

 agacagtggg atggcacagc aaagagagac tgctaccaag gtctatgata 4150

 tgcttaaaag tgaaaactta ttgggaaaac agattgatca cttattcatt 4200

 agtaatttac cagagattgt ggtggagtta ttgatgacgt tacatgagcc 4250

 agcaaattct agtgccagtc agagcactga cctctgtgac ttttcagggg 4300

 atttggatcc tgctcctaat ccacctcatt ttccatcgca tgtgattaaa 4350

 gcaacatttg cctatatcag caattgtcat aaaaccaagt taaaaagcat 4400

 tttagaaatt ctttccaaaa gccctgattc ctatcagaaa attcttcttg 4450

 ccatatgtga gcaagcagct gaaacaaata atgtttataa gaagcacaga 4500

 attcttaaaa tatatcacct gtttgttagt ttattactga aagatataaa 4550

 aagtggctta ggaggagctt gggcctttgt tcttcgagac gttatttata 4600

 ctttgattca ctatatcaac caaaggcctt cttgtatcat ggatgtgtca 4650

 ttacgtagct tctccctttg ttgtgactta ttaagtcagg tttgccagac 4700

 agccgtgact tactgtaagg atgctctaga aaaccatctt catgttattg 4750

 ttggtacact tatacccctt gtgtatgagc aggtggaggt tcagaaacag 4800

 gtattggact tgttgaaata cttagtgata gataacaagg ataatgaaaa 4850

 cctctatatc acgattaagc ttttagatcc ttttcctgac catgttgttt 4900

 ttaaggattt gcgtattact cagcaaaaaa tcaaatacag tagaggaccc 4950

 ttttcactct tggaggaaat taaccatttt ctctcagtaa gtgtttatga 5000

 tgcacttcca ttgacaagac ttgaaggact aaaggatctt cgaagacaac 5050

 tggaactaca taaagatcag atggtggaca ttatgagagc ttctcaggat 5100

 aatccgcaag atgggattat ggtgaaacta gttgtcaatt tgttgcagtt 5150

 atccaagatg gcaataaacc acactggtga aaaagaagtt ctagaggctg 5200

 ttggaagctg cttgggagaa gtgggtccta tagatttctc taccatagct 5250

 atacaacata gtaaagatgc atcttatacc aaggccctta agttatttga 5300

 agataaagaa cttcagtgga ccttcataat gctgacctac ctgaataaca 5350

 cactggtaga agattgtgtc aaagttcgat cagcagctgt tacctgtttg 5400

 aaaaacattt tagccacaaa gactggacat agtttctggg agatttataa 5450

 gatgacaaca gatccaatgc tggcctatct acagcctttt agaacatcaa 5500

 gaaaaaagtt tttagaagta cccagatttg acaaagaaaa cccttttgaa 5550

 ggcctggatg atataaatct gtggattcct ctaagtgaaa atcatgacat 5600

 ttggataaag acactgactt gtgctttttt ggacagtgga ggcacaaaat 5650

 gtgaaattct tcaattatta aagccaatgt gtgaagtgaa aactgacttt 5700

 tgtcagactg tacttccata cttgattcat gatattttac tccaagatac 5750

 aaatgaatca tggagaaatc tgctttctac acatgttcag ggatttttca 5800

 ccagctgtct tcgacacttc tcgcaaacga gccgatccac aacccctgca 5850

 aacttggatt cagagtcaga gcactttttc cgatgctgtt tggataaaaa 5900

 atcacaaaga acaatgcttg ctgttgtgga ctacatgaga agacaaaaga 5950

 gaccttcttc aggaacaatt tttaatgatg ctttctggct ggatttaaat 6000

 tatctagaag ttgccaaggt agctcagtct tgtgctgctc actttacagc 6050

 tttactctat gcagaaatct atgcagataa gaaaagtatg gatgatcaag 6100

 agaaaagaag tcttgcattt gaagaaggaa gccagagtac aactatttct 6150

 agcttgagtg aaaaaagtaa agaagaaact ggaataagtt tacaggatct 6200

 tctcttagaa atctacagaa gtatagggga gccagatagt ttgtatggct 6250

 gtggtggagg gaagatgtta caacccatta ctagactacg aacatatgaa 6300

 cacgaagcaa tgtggggcaa agccctagta acatatgacc tcgaaacagc 6350

 aatcccctca tcaacacgcc aggcaggaat cattcaggcc ttgcagaatt 6400

 tgggactctg ccatattctt tccgtctatt taaaaggatt ggattatgaa 6450

 aataaagact ggtgtcctga actagaagaa cttcattacc aagcagcatg 6500

 gaggaatatg cagtgggacc attgcacttc cgtcagcaaa gaagtagaag 6550

 gaaccagtta ccatgaatca ttgtacaatg ctctacaatc tctaagagac 6600

 agagaattct ctacatttta tgaaagtctc aaatatgcca gagtaaaaga 6650

 agtggaagag atgtgtaagc gcagccttga gtctgtgtat tcgctctatc 6700

 ccacacttag caggttgcag gccattggag agctggaaag cattggggag 6750

 cttttctcaa gatcagtcac acatagacaa ctctctgaag tatatattaa 6800

 gtggcagaaa cactcccagc ttctcaagga cagtgatttt agttttcagg 6850

 agcctatcat ggctctacgc acagtcattt tggagatcct gatggaaaag 6900

 gaaatggaca actcacaaag agaatgtatt aaggacattc tcaccaaaca 6950

 ccttgtagaa ctctctatac tggccagaac tttcaagaac actcagctcc 7000

 ctgaaagggc aatatttcaa attaaacagt acaattcagt tagctgtgga 7050

 gtctctgagt ggcagctgga agaagcacaa gtattctggg caaaaaagga 7100

 gcagagtctt gccctgagta ttctcaagca aatgatcaag aagttggatg 7150

 ccagctgtgc agcgaacaat cccagcctaa aacttacata cacagaatgt 7200

 ctgagggttt gtggcaactg gttagcagaa acgtgcttag aaaatcctgc 7250

 ggtcatcatg cagacctatc tagaaaaggc agtagaagtt gctggaaatt 7300

 atgatggaga aagtagtgat gagctaagaa atggaaaaat gaaggcattt 7350

 ctctcattag cccggttttc agatactcaa taccaaagaa ttgaaaacta 7400

 catgaaatca tcggaatttg aaaacaagca agctctcctg aaaagagcca 7450

 aagaggaagt aggtctcctt agggaacata aaattcagac aaacagatac 7500

 acagtaaagg ttcagcgaga gctggagttg gatgaattag ccctgcgtgc 7550

 actgaaagag gatcgtaaac gcttcttatg taaagcagtt gaaaattata 7600

 tcaactgctt attaagtgga gaagaacatg atatgtgggt attccggctt 7650

 tgttccctct ggcttgaaaa ttctggagtt tctgaagtca atggcatgat 7700

 gaagagagac ggaatgaaga ttccaacata taaatttttg cctcttatgt 7750

 accaattggc tgctagaatg gggaccaaga tgatgggagg cctaggattt 7800

 catgaagtcc tcaataatct aatctctaga atttcaatgg atcaccccca 7850

 tcacactttg tttattatac tggccttagc aaatgcaaac agagatgaat 7900

 ttctgactaa accagaggta gccagaagaa gcagaataac taaaaatgtg 7950

 cctaaacaaa gctctcagct tgatgaggat cgaacagagg ctgcaaatag 8000

 aataatatgt actatcagaa gtaggagacc tcagatggtc agaagtgttg 8050

 aggcactttg tgatgcttat attatattag caaacttaga tgccactcag 8100

 tggaagactc agagaaaagg cataaatatt ccagcagacc agccaattac 8150

 taaacttaag aatttagaag atgttgttgt ccctactatg gaaattaagg 8200

 tggaccacac aggagaatat ggaaatctgg tgactataca gtcatttaaa 8250

 gcagaatttc gcttagcagg aggtgtaaat ttaccaaaaa taatagattg 8300

 tgtaggttcc gatggcaagg agaggagaca gcttgttaag ggccgtgatg 8350

 acctgagaca agatgctgtc atgcaacagg tcttccagat gtgtaataca 8400

 ttactgcaga gaaacacgga aactaggaag aggaaattaa ctatctgtac 8450

 ttataaggtg gttcccctct ctcagcgaag tggtgttctt gaatggtgca 8500

 caggaactgt ccccattggt gaatttcttg ttaacaatga agatggtgct 8550

 cataaaagat acaggccaaa tgatttcagt gcctttcagt gccaaaagaa 8600

 aatgatggag gtgcaaaaaa agtcttttga agagaaatat gaagtcttca 8650

 tggatgtttg ccaaaatttt caaccagttt tccgttactt ctgcatggaa 8700

 aaattcttgg atccagctat ttggtttgag aagcgattgg cttatacgcg 8750

 cagtgtagct acttcttcta ttgttggtta catacttgga cttggtgata 8800

 gacatgtaca gaatatcttg ataaatgagc agtcagcaga acttgtacat 8850

 atagatctag gtgttgcttt tgaacagggc aaaatccttc ctactcctga 8900

 gacagttcct tttagactca ccagagatat tgtggatggc atgggcatta 8950

 cgggtgttga aggtgtcttc agaagatgct gtgagaaaac catggaagtg 9000

 atgagaaact ctcaggaaac tctgttaacc attgtagagg tccttctata 9050

 tgatccactc tttgactgga ccatgaatcc tttgaaagct ttgtatttac 9100

 agcagaggcc ggaagatgaa actgagcttc accctactct gaatgcagat 9150

 gaccaagaat gcaaacgaaa tctcagtgat attgaccaga gtttcaacaa 9200

 agtagctgaa cgtgtcttaa tgagactaca agagaaactg aaaggagtgg 9250

 aagaaggcac tgtgctcagt gttggtggac aagtgaattt gctcatacag 9300

 caggccatag accccaaaaa tctcagccga cttttcccag gatggaaagc 9350

 ttgggtgtga tcttcagtat atgaattacc ctttcattca gcctttagaa 9400

 attatatttt agcctttatt tttaacctgc caacatactt taagtaggga 9450

 ttaatattta agtgaactat tgtgggtttt tttgaatgtt ggttttaata 9500

 cttgatttaa tcaccactca aaaatgtttt gatggtctta aggaacatct 9550

 ctgctttcac tctttagaaa taatggtcat tcgggctggg cgcagcggct 9600

 cacgcctgta atcccagcac tttgggaggc cgaggtgagc ggatcacaag 9650

 gtcaggagtt cgagaccagc ctggccaaga gaccagcctg gccagtatgg 9700

 tgaaaccctg tctctactaa aaatacaaaa attagccgag catggtggcg 9750

 ggcacctgta gtcccagcta ctcgagaggc tgaggcagga gaatctcttg 9800

 aacctgggag gtgaaggttg ctgtgggcca aaatcatgcc attgcactcc 9850

 agcctgggtg acaagagcga aactccatct caaaaa 9886

<210> 2302
<211> 3056
<212> PRT
<213> Homo sapien

<400> 2302
 Met Ser Leu Val Leu Asn Asp Leu Leu Ile Cys Cys Arg Gln Leu
   1               5                  10                  15

 Glu His Asp Arg Ala Thr Glu Arg Lys Lys Glu Val Glu Lys Phe
                  20                  25                  30

 Lys Arg Leu Ile Arg Asp Pro Glu Thr Ile Lys His Leu Asp Arg
                  35                  40                  45

 His Ser Asp Ser Lys Gln Gly Lys Tyr Leu Asn Trp Asp Ala Val
                  50                  55                  60

 Phe Arg Phe Leu Gln Lys Tyr Ile Gln Lys Glu Thr Glu Cys Leu
                  65                  70                  75

 Arg Ile Ala Lys Pro Asn Val Ser Ala Ser Thr Gln Ala Ser Arg
                  80                  85                  90

 Gln Lys Lys Met Gln Glu Ile Ser Ser Leu Val Lys Tyr Phe Ile
                  95                 100                 105

 Lys Cys Ala Asn Arg Arg Ala Pro Arg Leu Lys Cys Gln Glu Leu
                 110                 115                 120

 Leu Asn Tyr Ile Met Asp Thr Val Lys Asp Ser Ser Asn Gly Ala
                 125                 130                 135

 Ile Tyr Gly Ala Asp Cys Ser Asn Ile Leu Leu Lys Asp Ile Leu
                 140                 145                 150

 Ser Val Arg Lys Tyr Trp Cys Glu Ile Ser Gln Gln Gln Trp Leu
                 155                 160                 165

 Glu Leu Phe Ser Val Tyr Phe Arg Leu Tyr Leu Lys Pro Ser Gln
                 170                 175                 180

 Asp Val His Arg Val Leu Val Ala Arg Ile Ile His Ala Val Thr
                 185                 190                 195

 Lys Gly Cys Cys Ser Gln Thr Asp Gly Leu Asn Ser Lys Phe Leu
                 200                 205                 210

 Asp Phe Phe Ser Lys Ala Ile Gln Cys Ala Arg Gln Glu Lys Ser
                 215                 220                 225

 Ser Ser Gly Leu Asn His Ile Leu Ala Ala Leu Thr Ile Phe Leu
                 230                 235                 240

 Lys Thr Leu Ala Val Asn Phe Arg Ile Arg Val Cys Glu Leu Gly
                 245                 250                 255

 Asp Glu Ile Leu Pro Thr Leu Leu Tyr Ile Trp Thr Gln His Arg
                 260                 265                 270

 Leu Asn Asp Ser Leu Lys Glu Val Ile Ile Glu Leu Phe Gln Leu
                 275                 280                 285

 Gln Ile Tyr Ile His His Pro Lys Gly Ala Lys Thr Gln Glu Lys
                 290                 295                 300

 Gly Ala Tyr Glu Ser Thr Lys Trp Arg Ser Ile Leu Tyr Asn Leu
                 305                 310                 315

 Tyr Asp Leu Leu Val Asn Glu Ile Ser His Ile Gly Ser Arg Gly
                 320                 325                 330

 Lys Tyr Ser Ser Gly Phe Arg Asn Ile Ala Val Lys Glu Asn Leu
                 335                 340                 345

 Ile Glu Leu Met Ala Asp Ile Cys His Gln Val Phe Asn Glu Asp
                 350                 355                 360

 Thr Arg Ser Leu Glu Ile Ser Gln Ser Tyr Thr Thr Thr Gln Arg
                 365                 370                 375

 Glu Ser Ser Asp Tyr Ser Val Pro Cys Lys Arg Lys Lys Ile Glu
                 380                 385                 390

 Leu Gly Trp Glu Val Ile Lys Asp His Leu Gln Lys Ser Gln Asn
                 395                 400                 405

 Asp Phe Asp Leu Val Pro Trp Leu Gln Ile Ala Thr Gln Leu Ile
                 410                 415                 420

 Ser Lys Tyr Pro Ala Ser Leu Pro Asn Cys Glu Leu Ser Pro Leu
                 425                 430                 435

 Leu Met Ile Leu Ser Gln Leu Leu Pro Gln Gln Arg His Gly Glu
                 440                 445                 450

 Arg Thr Pro Tyr Val Leu Arg Cys Leu Thr Glu Val Ala Leu Cys
                 455                 460                 465

 Gln Asp Lys Arg Ser Asn Leu Glu Ser Ser Gln Lys Ser Asp Leu
                 470                 475                 480

 Leu Lys Leu Trp Asn Lys Ile Trp Cys Ile Thr Phe Arg Gly Ile
                 485                 490                 495

 Ser Ser Glu Gln Ile Gln Ala Glu Asn Phe Gly Leu Leu Gly Ala
                 500                 505                 510

 Ile Ile Gln Gly Ser Leu Val Glu Val Asp Arg Glu Phe Trp Lys
                 515                 520                 525

 Leu Phe Thr Gly Ser Ala Cys Arg Pro Ser Cys Pro Ala Val Cys
                 530                 535                 540

 Cys Leu Thr Leu Ala Leu Thr Thr Ser Ile Val Pro Gly Ala Val
                 545                 550                 555

 Lys Met Gly Ile Glu Gln Asn Met Cys Glu Val Asn Arg Ser Phe
                 560                 565                 570

 Ser Leu Lys Glu Ser Ile Met Lys Trp Leu Leu Phe Tyr Gln Leu
                 575                 580                 585

 Glu Gly Asp Leu Glu Asn Ser Thr Glu Val Pro Pro Ile Leu His
                 590                 595                 600

 Ser Asn Phe Pro His Leu Val Leu Glu Lys Ile Leu Val Ser Leu
                 605                 610                 615

 Thr Met Lys Asn Cys Lys Ala Ala Met Asn Phe Phe Gln Ser Val
                 620                 625                 630

 Pro Glu Cys Glu His His Gln Lys Asp Lys Glu Glu Leu Ser Phe
                 635                 640                 645

 Ser Glu Val Glu Glu Leu Phe Leu Gln Thr Thr Phe Asp Lys Met
                 650                 655                 660

 Asp Phe Leu Thr Ile Val Arg Glu Cys Gly Ile Glu Lys His Gln
                 665                 670                 675

 Ser Ser Ile Gly Phe Ser Val His Gln Asn Leu Lys Glu Ser Leu
                 680                 685                 690

 Asp Arg Cys Leu Leu Gly Leu Ser Glu Gln Leu Leu Asn Asn Tyr
                 695                 700                 705

 Ser Ser Glu Ile Thr Asn Ser Glu Thr Leu Val Arg Cys Ser Arg
                 710                 715                 720

 Leu Leu Val Gly Val Leu Gly Cys Tyr Cys Tyr Met Gly Val Ile
                 725                 730                 735

 Ala Glu Glu Glu Ala Tyr Lys Ser Glu Leu Phe Gln Lys Ala Asn
                 740                 745                 750

 Ser Leu Met Gln Cys Ala Gly Glu Ser Ile Thr Leu Phe Lys Asn
                 755                 760                 765

 Lys Thr Asn Glu Glu Phe Arg Ile Gly Ser Leu Arg Asn Met Met
                 770                 775                 780

 Gln Leu Cys Thr Arg Cys Leu Ser Asn Cys Thr Lys Lys Ser Pro
                 785                 790                 795

 Asn Lys Ile Ala Ser Gly Phe Phe Leu Arg Leu Leu Thr Ser Lys
                 800                 805                 810

 Leu Met Asn Asp Ile Ala Asp Ile Cys Lys Ser Leu Ala Ser Phe
                 815                 820                 825

 Ile Lys Lys Pro Phe Asp Arg Gly Glu Val Glu Ser Met Glu Asp
                 830                 835                 840

 Asp Thr Asn Gly Asn Leu Met Glu Val Glu Asp Gln Ser Ser Met
                 845                 850                 855

 Asn Leu Phe Asn Asp Tyr Pro Asp Ser Ser Val Ser Asp Ala Asn
                 860                 865                 870

 Glu Pro Gly Glu Ser Gln Ser Thr Ile Gly Ala Ile Asn Pro Leu
                 875                 880                 885

 Ala Glu Glu Tyr Leu Ser Lys Gln Asp Leu Leu Phe Leu Asp Met
                 890                 895                 900

 Leu Lys Phe Leu Cys Leu Cys Val Thr Thr Ala Gln Thr Asn Thr
                 905                 910                 915

 Val Ser Phe Arg Ala Ala Asp Ile Arg Arg Lys Leu Leu Met Leu
                 920                 925                 930

 Ile Asp Ser Ser Thr Leu Glu Pro Thr Lys Ser Leu His Leu His
                 935                 940                 945

 Met Tyr Leu Met Leu Leu Lys Glu Leu Pro Gly Glu Glu Tyr Pro
                 950                 955                 960

 Leu Pro Met Glu Asp Val Leu Glu Leu Leu Lys Pro Leu Ser Asn
                 965                 970                 975

 Val Cys Ser Leu Tyr Arg Arg Asp Gln Asp Val Cys Lys Thr Ile
                 980                 985                 990

 Leu Asn His Val Leu His Val Val Lys Asn Leu Gly Gln Ser Asn
                 995                1000                1005

 Met Asp Ser Glu Asn Thr Arg Asp Ala Gln Gly Gln Phe Leu Thr
                1010                1015                1020

 Val Ile Gly Ala Phe Trp His Leu Thr Lys Glu Arg Lys Tyr Ile
                1025                1030                1035

 Phe Ser Val Arg Met Ala Leu Val Asn Cys Leu Lys Thr Leu Leu
                1040                1045                1050

 Glu Ala Asp Pro Tyr Ser Lys Trp Ala Ile Leu Asn Val Met Gly
                1055                1060                1065

 Lys Asp Phe Pro Val Asn Glu Val Phe Thr Gln Phe Leu Ala Asp
                1070                1075                1080

 Asn His His Gln Val Arg Met Leu Ala Ala Glu Ser Ile Asn Arg
                1085                1090                1095

 Leu Phe Gln Asp Thr Lys Gly Asp Ser Ser Arg Leu Leu Lys Ala
                1100                1105                1110

 Leu Pro Leu Lys Leu Gln Gln Thr Ala Phe Glu Asn Ala Tyr Leu
                1115                1120                1125

 Lys Ala Gln Glu Gly Met Arg Glu Met Ser His Ser Ala Glu Asn
                1130                1135                1140

 Pro Glu Thr Leu Asp Glu Ile Tyr Asn Arg Lys Ser Val Leu Leu
                1145                1150                1155

 Thr Leu Ile Ala Val Val Leu Ser Cys Ser Pro Ile Cys Glu Lys
                1160                1165                1170

 Gln Ala Leu Phe Ala Leu Cys Lys Ser Val Lys Glu Asn Gly Leu
                1175                1180                1185

 Glu Pro His Leu Val Lys Lys Val Leu Glu Lys Val Ser Glu Thr
                1190                1195                1200

 Phe Gly Tyr Arg Arg Leu Glu Asp Phe Met Ala Ser His Leu Asp
                1205                1210                1215

 Tyr Leu Val Leu Glu Trp Leu Asn Leu Gln Asp Thr Glu Tyr Asn
                1220                1225                1230

 Leu Ser Ser Phe Pro Phe Ile Leu Leu Asn Tyr Thr Asn Ile Glu
                1235                1240                1245

 Asp Phe Tyr Arg Ser Cys Tyr Lys Val Leu Ile Pro His Leu Val
                1250                1255                1260

 Ile Arg Ser His Phe Asp Glu Val Lys Ser Ile Ala Asn Gln Ile
                1265                1270                1275

 Gln Glu Asp Trp Lys Ser Leu Leu Thr Asp Cys Phe Pro Lys Ile
                1280                1285                1290

 Leu Val Asn Ile Leu Pro Tyr Phe Ala Tyr Glu Gly Thr Arg Asp
                1295                1300                1305

 Ser Gly Met Ala Gln Gln Arg Glu Thr Ala Thr Lys Val Tyr Asp
                1310                1315                1320

 Met Leu Lys Ser Glu Asn Leu Leu Gly Lys Gln Ile Asp His Leu
                1325                1330                1335

 Phe Ile Ser Asn Leu Pro Glu Ile Val Val Glu Leu Leu Met Thr
                1340                1345                1350

 Leu His Glu Pro Ala Asn Ser Ser Ala Ser Gln Ser Thr Asp Leu
                1355                1360                1365

 Cys Asp Phe Ser Gly Asp Leu Asp Pro Ala Pro Asn Pro Pro His
                1370                1375                1380

 Phe Pro Ser His Val Ile Lys Ala Thr Phe Ala Tyr Ile Ser Asn
                1385                1390                1395

 Cys His Lys Thr Lys Leu Lys Ser Ile Leu Glu Ile Leu Ser Lys
                1400                1405                1410

 Ser Pro Asp Ser Tyr Gln Lys Ile Leu Leu Ala Ile Cys Glu Gln
                1415                1420                1425

 Ala Ala Glu Thr Asn Asn Val Tyr Lys Lys His Arg Ile Leu Lys
                1430                1435                1440

 Ile Tyr His Leu Phe Val Ser Leu Leu Leu Lys Asp Ile Lys Ser
                1445                1450                1455

 Gly Leu Gly Gly Ala Trp Ala Phe Val Leu Arg Asp Val Ile Tyr
                1460                1465                1470

 Thr Leu Ile His Tyr Ile Asn Gln Arg Pro Ser Cys Ile Met Asp
                1475                1480                1485

 Val Ser Leu Arg Ser Phe Ser Leu Cys Cys Asp Leu Leu Ser Gln
                1490                1495                1500

 Val Cys Gln Thr Ala Val Thr Tyr Cys Lys Asp Ala Leu Glu Asn
                1505                1510                1515

 His Leu His Val Ile Val Gly Thr Leu Ile Pro Leu Val Tyr Glu
                1520                1525                1530

 Gln Val Glu Val Gln Lys Gln Val Leu Asp Leu Leu Lys Tyr Leu
                1535                1540                1545

 Val Ile Asp Asn Lys Asp Asn Glu Asn Leu Tyr Ile Thr Ile Lys
                1550                1555                1560

 Leu Leu Asp Pro Phe Pro Asp His Val Val Phe Lys Asp Leu Arg
                1565                1570                1575

 Ile Thr Gln Gln Lys Ile Lys Tyr Ser Arg Gly Pro Phe Ser Leu
                1580                1585                1590

 Leu Glu Glu Ile Asn His Phe Leu Ser Val Ser Val Tyr Asp Ala
                1595                1600                1605

 Leu Pro Leu Thr Arg Leu Glu Gly Leu Lys Asp Leu Arg Arg Gln
                1610                1615                1620

 Leu Glu Leu His Lys Asp Gln Met Val Asp Ile Met Arg Ala Ser
                1625                1630                1635

 Gln Asp Asn Pro Gln Asp Gly Ile Met Val Lys Leu Val Val Asn
                1640                1645                1650

 Leu Leu Gln Leu Ser Lys Met Ala Ile Asn His Thr Gly Glu Lys
                1655                1660                1665

 Glu Val Leu Glu Ala Val Gly Ser Cys Leu Gly Glu Val Gly Pro
                1670                1675                1680

 Ile Asp Phe Ser Thr Ile Ala Ile Gln His Ser Lys Asp Ala Ser
                1685                1690                1695

 Tyr Thr Lys Ala Leu Lys Leu Phe Glu Asp Lys Glu Leu Gln Trp
                1700                1705                1710

 Thr Phe Ile Met Leu Thr Tyr Leu Asn Asn Thr Leu Val Glu Asp
                1715                1720                1725

 Cys Val Lys Val Arg Ser Ala Ala Val Thr Cys Leu Lys Asn Ile
                1730                1735                1740

 Leu Ala Thr Lys Thr Gly His Ser Phe Trp Glu Ile Tyr Lys Met
                1745                1750                1755

 Thr Thr Asp Pro Met Leu Ala Tyr Leu Gln Pro Phe Arg Thr Ser
                1760                1765                1770

 Arg Lys Lys Phe Leu Glu Val Pro Arg Phe Asp Lys Glu Asn Pro
                1775                1780                1785

 Phe Glu Gly Leu Asp Asp Ile Asn Leu Trp Ile Pro Leu Ser Glu
                1790                1795                1800

 Asn His Asp Ile Trp Ile Lys Thr Leu Thr Cys Ala Phe Leu Asp
                1805                1810                1815

 Ser Gly Gly Thr Lys Cys Glu Ile Leu Gln Leu Leu Lys Pro Met
                1820                1825                1830

 Cys Glu Val Lys Thr Asp Phe Cys Gln Thr Val Leu Pro Tyr Leu
                1835                1840                1845

 Ile His Asp Ile Leu Leu Gln Asp Thr Asn Glu Ser Trp Arg Asn
                1850                1855                1860

 Leu Leu Ser Thr His Val Gln Gly Phe Phe Thr Ser Cys Leu Arg
                1865                1870                1875

 His Phe Ser Gln Thr Ser Arg Ser Thr Thr Pro Ala Asn Leu Asp
                1880                1885                1890

 Ser Glu Ser Glu His Phe Phe Arg Cys Cys Leu Asp Lys Lys Ser
                1895                1900                1905

 Gln Arg Thr Met Leu Ala Val Val Asp Tyr Met Arg Arg Gln Lys
                1910                1915                1920

 Arg Pro Ser Ser Gly Thr Ile Phe Asn Asp Ala Phe Trp Leu Asp
                1925                1930                1935

 Leu Asn Tyr Leu Glu Val Ala Lys Val Ala Gln Ser Cys Ala Ala
                1940                1945                1950

 His Phe Thr Ala Leu Leu Tyr Ala Glu Ile Tyr Ala Asp Lys Lys
                1955                1960                1965

 Ser Met Asp Asp Gln Glu Lys Arg Ser Leu Ala Phe Glu Glu Gly
                1970                1975                1980

 Ser Gln Ser Thr Thr Ile Ser Ser Leu Ser Glu Lys Ser Lys Glu
                1985                1990                1995

 Glu Thr Gly Ile Ser Leu Gln Asp Leu Leu Leu Glu Ile Tyr Arg
                2000                2005                2010

 Ser Ile Gly Glu Pro Asp Ser Leu Tyr Gly Cys Gly Gly Gly Lys
                2015                2020                2025

 Met Leu Gln Pro Ile Thr Arg Leu Arg Thr Tyr Glu His Glu Ala
                2030                2035                2040

 Met Trp Gly Lys Ala Leu Val Thr Tyr Asp Leu Glu Thr Ala Ile
                2045                2050                2055

 Pro Ser Ser Thr Arg Gln Ala Gly Ile Ile Gln Ala Leu Gln Asn
                2060                2065                2070

 Leu Gly Leu Cys His Ile Leu Ser Val Tyr Leu Lys Gly Leu Asp
                2075                2080                2085

 Tyr Glu Asn Lys Asp Trp Cys Pro Glu Leu Glu Glu Leu His Tyr
                2090                2095                2100

 Gln Ala Ala Trp Arg Asn Met Gln Trp Asp His Cys Thr Ser Val
                2105                2110                2115

 Ser Lys Glu Val Glu Gly Thr Ser Tyr His Glu Ser Leu Tyr Asn
                2120                2125                2130

 Ala Leu Gln Ser Leu Arg Asp Arg Glu Phe Ser Thr Phe Tyr Glu
                2135                2140                2145

 Ser Leu Lys Tyr Ala Arg Val Lys Glu Val Glu Glu Met Cys Lys
                2150                2155                2160

 Arg Ser Leu Glu Ser Val Tyr Ser Leu Tyr Pro Thr Leu Ser Arg
                2165                2170                2175

 Leu Gln Ala Ile Gly Glu Leu Glu Ser Ile Gly Glu Leu Phe Ser
                2180                2185                2190

 Arg Ser Val Thr His Arg Gln Leu Ser Glu Val Tyr Ile Lys Trp
                2195                2200                2205

 Gln Lys His Ser Gln Leu Leu Lys Asp Ser Asp Phe Ser Phe Gln
                2210                2215                2220

 Glu Pro Ile Met Ala Leu Arg Thr Val Ile Leu Glu Ile Leu Met
                2225                2230                2235

 Glu Lys Glu Met Asp Asn Ser Gln Arg Glu Cys Ile Lys Asp Ile
                2240                2245                2250

 Leu Thr Lys His Leu Val Glu Leu Ser Ile Leu Ala Arg Thr Phe
                2255                2260                2265

 Lys Asn Thr Gln Leu Pro Glu Arg Ala Ile Phe Gln Ile Lys Gln
                2270                2275                2280

 Tyr Asn Ser Val Ser Cys Gly Val Ser Glu Trp Gln Leu Glu Glu
                2285                2290                2295

 Ala Gln Val Phe Trp Ala Lys Lys Glu Gln Ser Leu Ala Leu Ser
                2300                2305                2310

 Ile Leu Lys Gln Met Ile Lys Lys Leu Asp Ala Ser Cys Ala Ala
                2315                2320                2325

 Asn Asn Pro Ser Leu Lys Leu Thr Tyr Thr Glu Cys Leu Arg Val
                2330                2335                2340

 Cys Gly Asn Trp Leu Ala Glu Thr Cys Leu Glu Asn Pro Ala Val
                2345                2350                2355

 Ile Met Gln Thr Tyr Leu Glu Lys Ala Val Glu Val Ala Gly Asn
                2360                2365                2370

 Tyr Asp Gly Glu Ser Ser Asp Glu Leu Arg Asn Gly Lys Met Lys
                2375                2380                2385

 Ala Phe Leu Ser Leu Ala Arg Phe Ser Asp Thr Gln Tyr Gln Arg
                2390                2395                2400

 Ile Glu Asn Tyr Met Lys Ser Ser Glu Phe Glu Asn Lys Gln Ala
                2405                2410                2415

 Leu Leu Lys Arg Ala Lys Glu Glu Val Gly Leu Leu Arg Glu His
                2420                2425                2430

 Lys Ile Gln Thr Asn Arg Tyr Thr Val Lys Val Gln Arg Glu Leu
                2435                2440                2445

 Glu Leu Asp Glu Leu Ala Leu Arg Ala Leu Lys Glu Asp Arg Lys
                2450                2455                2460

 Arg Phe Leu Cys Lys Ala Val Glu Asn Tyr Ile Asn Cys Leu Leu
                2465                2470                2475

 Ser Gly Glu Glu His Asp Met Trp Val Phe Arg Leu Cys Ser Leu
                2480                2485                2490

 Trp Leu Glu Asn Ser Gly Val Ser Glu Val Asn Gly Met Met Lys
                2495                2500                2505

 Arg Asp Gly Met Lys Ile Pro Thr Tyr Lys Phe Leu Pro Leu Met
                2510                2515                2520

 Tyr Gln Leu Ala Ala Arg Met Gly Thr Lys Met Met Gly Gly Leu
                2525                2530                2535

 Gly Phe His Glu Val Leu Asn Asn Leu Ile Ser Arg Ile Ser Met
                2540                2545                2550

 Asp His Pro His His Thr Leu Phe Ile Ile Leu Ala Leu Ala Asn
                2555                2560                2565

 Ala Asn Arg Asp Glu Phe Leu Thr Lys Pro Glu Val Ala Arg Arg
                2570                2575                2580

 Ser Arg Ile Thr Lys Asn Val Pro Lys Gln Ser Ser Gln Leu Asp
                2585                2590                2595

 Glu Asp Arg Thr Glu Ala Ala Asn Arg Ile Ile Cys Thr Ile Arg
                2600                2605                2610

 Ser Arg Arg Pro Gln Met Val Arg Ser Val Glu Ala Leu Cys Asp
                2615                2620                2625

 Ala Tyr Ile Ile Leu Ala Asn Leu Asp Ala Thr Gln Trp Lys Thr
                2630                2635                2640

 Gln Arg Lys Gly Ile Asn Ile Pro Ala Asp Gln Pro Ile Thr Lys
                2645                2650                2655

 Leu Lys Asn Leu Glu Asp Val Val Val Pro Thr Met Glu Ile Lys
                2660                2665                2670

 Val Asp His Thr Gly Glu Tyr Gly Asn Leu Val Thr Ile Gln Ser
                2675                2680                2685

 Phe Lys Ala Glu Phe Arg Leu Ala Gly Gly Val Asn Leu Pro Lys
                2690                2695                2700

 Ile Ile Asp Cys Val Gly Ser Asp Gly Lys Glu Arg Arg Gln Leu
                2705                2710                2715

 Val Lys Gly Arg Asp Asp Leu Arg Gln Asp Ala Val Met Gln Gln
                2720                2725                2730

 Val Phe Gln Met Cys Asn Thr Leu Leu Gln Arg Asn Thr Glu Thr
                2735                2740                2745

 Arg Lys Arg Lys Leu Thr Ile Cys Thr Tyr Lys Val Val Pro Leu
                2750                2755                2760

 Ser Gln Arg Ser Gly Val Leu Glu Trp Cys Thr Gly Thr Val Pro
                2765                2770                2775

 Ile Gly Glu Phe Leu Val Asn Asn Glu Asp Gly Ala His Lys Arg
                2780                2785                2790

 Tyr Arg Pro Asn Asp Phe Ser Ala Phe Gln Cys Gln Lys Lys Met
                2795                2800                2805

 Met Glu Val Gln Lys Lys Ser Phe Glu Glu Lys Tyr Glu Val Phe
                2810                2815                2820

 Met Asp Val Cys Gln Asn Phe Gln Pro Val Phe Arg Tyr Phe Cys
                2825                2830                2835

 Met Glu Lys Phe Leu Asp Pro Ala Ile Trp Phe Glu Lys Arg Leu
                2840                2845                2850

 Ala Tyr Thr Arg Ser Val Ala Thr Ser Ser Ile Val Gly Tyr Ile
                2855                2860                2865

 Leu Gly Leu Gly Asp Arg His Val Gln Asn Ile Leu Ile Asn Glu
                2870                2875                2880

 Gln Ser Ala Glu Leu Val His Ile Asp Leu Gly Val Ala Phe Glu
                2885                2890                2895

 Gln Gly Lys Ile Leu Pro Thr Pro Glu Thr Val Pro Phe Arg Leu
                2900                2905                2910

 Thr Arg Asp Ile Val Asp Gly Met Gly Ile Thr Gly Val Glu Gly
                2915                2920                2925

 Val Phe Arg Arg Cys Cys Glu Lys Thr Met Glu Val Met Arg Asn
                2930                2935                2940

 Ser Gln Glu Thr Leu Leu Thr Ile Val Glu Val Leu Leu Tyr Asp
                2945                2950                2955

 Pro Leu Phe Asp Trp Thr Met Asn Pro Leu Lys Ala Leu Tyr Leu
                2960                2965                2970

 Gln Gln Arg Pro Glu Asp Glu Thr Glu Leu His Pro Thr Leu Asn
                2975                2980                2985

 Ala Asp Asp Gln Glu Cys Lys Arg Asn Leu Ser Asp Ile Asp Gln
                2990                2995                3000

 Ser Phe Asn Lys Val Ala Glu Arg Val Leu Met Arg Leu Gln Glu
                3005                3010                3015

 Lys Leu Lys Gly Val Glu Glu Gly Thr Val Leu Ser Val Gly Gly
                3020                3025                3030

 Gln Val Asn Leu Leu Ile Gln Gln Ala Ile Asp Pro Lys Asn Leu
                3035                3040                3045

 Ser Arg Leu Phe Pro Gly Trp Lys Ala Trp Val
                3050                3055

<210> 2303
<211> 1909
<212> DNA
<213> Homo sapien

<400> 2303
 gaggtgtttc ccttagctat ggaaactcta taagagagat ccagcttgcc 50

 tcctcttgag cagtcagcaa cagggtcccg tccttgacac ctcagcctct 100

 acaggactga gaagaagtaa aaccgtttgc tggggctggc ctgactcacc 150

 agctgccatg cagcagccct tcaattaccc atatccccag atctactggg 200

 tggacagcag tgccagctct ccctgggccc ctccaggcac agttcttccc 250

 tgtccaacct ctgtgcccag aaggcctggt caaaggaggc caccaccacc 300

 accgccaccg ccaccactac cacctccgcc gccgccgcca ccactgcctc 350

 cactaccgct gccacccctg aagaagagag ggaaccacag cacaggcctg 400

 tgtctccttg tgatgttttt catggttctg gttgccttgg taggattggg 450

 cctggggatg tttcagctct tccacctaca gaaggagctg gcagaactcc 500

 gagagtctac cagccagatg cacacagcat catctttgga gaagcaaata 550

 ggccacccca gtccaccccc tgaaaaaaag gagctgagga aagtggccca 600

 tttaacaggc aagtccaact caaggtccat gcctctggaa tgggaagaca 650

 cctatggaat tgtcctgctt tctggagtga agtataagaa gggtggcctt 700

 gtgatcaatg aaactgggct gtactttgta tattccaaag tatacttccg 750

 gggtcaatct tgcaacaacc tgcccctgag ccacaaggtc tacatgagga 800

 actctaagta tccccaggat ctggtgatga tggaggggaa gatgatgagc 850

 tactgcacta ctgggcagat gtgggcccgc agcagctacc tgggggcagt 900

 gttcaatctt accagtgctg atcatttata tgtcaacgta tctgagctct 950

 ctctggtcaa ttttgaggaa tctcagacgt ttttcggctt atataagctc 1000

 taagagaagc actttgggat tctttccatt atgattcttt gttacaggca 1050

 ccgagaatgt tgtattcagt gagggtcttc ttacatgcat ttgaggtcaa 1100

 gtaagaagac atgaaccaag tggaccttga gaccacaggg ttcaaaatgt 1150

 ctgtagctcc tcaactcacc taatgtttat gagccagaca aatggaggaa 1200

 tatgacggaa gaacatagaa ctctgggctg ccatgtgaag agggagaagc 1250

 atgaaaaagc agctaccagg tgttctacac tcatcttagt gcctgagagt 1300

 atttaggcag attgaaaagg acacctttta actcacctct caaggtgggc 1350

 cttgctacct caagggggac tgtctttcag atacatggtt gtgacctgag 1400

 gatttaaggg atggaaaagg aagactagag gcttgcataa taagctaaag 1450

 aggctgaaag aggccaatgc cccactggca gcatcttcac ttctaaatgc 1500

 atatcctgag ccatcggtga aactaacaga taagcaagag agatgttttg 1550

 gggactcatt tcattcctaa cacagcatgt gtatttccag tgcaattgta 1600

 ggggtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtatgac taaagagaga 1650

 atgtagatat tgtgaagtac atattaggaa aatatgggtt gcatttggtc 1700

 aagattttga atgcttcctg acaatcaact ctaatagtgc ttaaaaatca 1750

 ttgattgtca gctactaatg atgttttcct ataatataat aaatatttat 1800

 gtagatgtgc atttttgtga aatgaaaaca tgtaataaaa agtatatgtt 1850

 aggatacaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaa 1909

<210> 2304
<211> 281
<212> PRT
<213> Homo sapien

<400> 2304
 Met Gln Gln Pro Phe Asn Tyr Pro Tyr Pro Gln Ile Tyr Trp Val
   1               5                  10                  15

 Asp Ser Ser Ala Ser Ser Pro Trp Ala Pro Pro Gly Thr Val Leu
                  20                  25                  30

 Pro Cys Pro Thr Ser Val Pro Arg Arg Pro Gly Gln Arg Arg Pro
                  35                  40                  45

 Pro Pro Pro Pro Pro Pro Pro Pro Leu Pro Pro Pro Pro Pro Pro
                  50                  55                  60

 Pro Pro Leu Pro Pro Leu Pro Leu Pro Pro Leu Lys Lys Arg Gly
                  65                  70                  75

 Asn His Ser Thr Gly Leu Cys Leu Leu Val Met Phe Phe Met Val
                  80                  85                  90

 Leu Val Ala Leu Val Gly Leu Gly Leu Gly Met Phe Gln Leu Phe
                  95                 100                 105

 His Leu Gln Lys Glu Leu Ala Glu Leu Arg Glu Ser Thr Ser Gln
                 110                 115                 120

 Met His Thr Ala Ser Ser Leu Glu Lys Gln Ile Gly His Pro Ser
                 125                 130                 135

 Pro Pro Pro Glu Lys Lys Glu Leu Arg Lys Val Ala His Leu Thr
                 140                 145                 150

 Gly Lys Ser Asn Ser Arg Ser Met Pro Leu Glu Trp Glu Asp Thr
                 155                 160                 165

 Tyr Gly Ile Val Leu Leu Ser Gly Val Lys Tyr Lys Lys Gly Gly
                 170                 175                 180

 Leu Val Ile Asn Glu Thr Gly Leu Tyr Phe Val Tyr Ser Lys Val
                 185                 190                 195

 Tyr Phe Arg Gly Gln Ser Cys Asn Asn Leu Pro Leu Ser His Lys
                 200                 205                 210

 Val Tyr Met Arg Asn Ser Lys Tyr Pro Gln Asp Leu Val Met Met
                 215                 220                 225

 Glu Gly Lys Met Met Ser Tyr Cys Thr Thr Gly Gln Met Trp Ala
                 230                 235                 240

 Arg Ser Ser Tyr Leu Gly Ala Val Phe Asn Leu Thr Ser Ala Asp
                 245                 250                 255

 His Leu Tyr Val Asn Val Ser Glu Leu Ser Leu Val Asn Phe Glu
                 260                 265                 270

 Glu Ser Gln Thr Phe Phe Gly Leu Tyr Lys Leu
                 275                 280

<210> 2305
<211> 3045
<212> DNA
<213> Homo sapien

<400> 2305
 actaagaccg caaggcattc atttcctcct acggtggatg cggacgccgg 50

 gaggaggaga gccccagaga gaggagctgg gagcggaggc gcaggcaatg 100

 ctcagccctg gatgtagctg agaggctggg agaagagacg accgctggag 150

 accgagcggc gtggggaaga cctagggggg tgggtggggg aagcagacag 200

 gagaacactc gaaatcaagc gctttacaga ttattttatt ttgtatagag 250

 aacacgtagc gactccgaag atcagcccca atgaacatgt cagtgttgac 300

 tttacaagaa tatgaattcg aaaagcagtt caacgagaat gaagccatcc 350

 aatggatgca ggaaaactgg aagaaatctt tcctgttttc tgctctgtat 400

 gctgccttta tattcggtgg tcggcaccta atgaataaac gagcaaagtt 450

 tgaactgagg aagccattag tgctctggtc tctgaccctt gcagtcttca 500

 gtatattcgg tgctcttcga actggtgctt atatggtgta cattttgatg 550

 accaaaggcc tgaagcagtc agtttgtgac cagggttttt acaatggacc 600

 tgtcagcaaa ttctgggctt atgcatttgt gctaagcaaa gcacccgaac 650

 taggagatac aatattcatt attctgagga agcagaagct gatcttcctg 700

 cactggtatc accacatcac tgtgctcctg tactcttggt actcctacaa 750

 agacatggtt gccgggggag gttggttcat gactatgaac tatggcgtgc 800

 acgccgtgat gtactcttac tatgccttgc gggcggcagg tttccgagtc 850

 tcccggaagt ttgccatgtt catcaccttg tcccagatca ctcagatgct 900

 gatgggctgt gtggttaact acctggtctt ctgctggatg cagcatgacc 950

 agtgtcactc tcactttcag aacatcttct ggtcctcact catgtacctc 1000

 agctaccttg tgctcttctg ccatttcttc tttgaggcct acatcggcaa 1050

 aatgaggaaa acaacgaaag ctgaatagtg ttggaactga ggaggaagcc 1100

 atagctcagg gtcatcaaga aaaataatag acaaaagaaa atggcacaag 1150

 gaatcacacg tggtgcagct aaaacaaaac aaaacatgag caaacacaaa 1200

 acccaaggca gcttagggat aattaggttg atttaaccca gtaagtttat 1250

 gatcctttta gggtgaggac tcactgagtg cacctccatc tccaagcact 1300

 gctgctggaa gaccccattc cctctttatc tatcaactct aggacaaggg 1350

 agaacaaaag caagccagaa gcagaggaga ctaatcaaag gcaaacaaag 1400

 gctattaaca cataggaaaa tatgtattta ctaagtgtca catttctcta 1450

 agatgaaaga tttttactct agaaactgtg cgagcacaac acacacaatc 1500

 ctttctaact ttatggacac taaactggag ccaatagaaa agacaaaaat 1550

 gaaagagaca cagggtgtat atctagaacg ataatgcttt tgcagaaact 1600

 aaagcctttt taagaaatgc cagctgctgt agaccccatg agaaaagatg 1650

 tcttaatcat ccttatgaaa acagatgtaa acaactatat ttcaactaac 1700

 ttcatcttca ctgcatagcc tcaggctagt gagtttgcca aaaccaaagg 1750

 gggtgaatac ttccccaaga ttcttcctgg gaggatggaa acagtgcagc 1800

 ccaggtccca tgggggcagc tccatcccag agcatttctg atagttgaac 1850

 tgtaatttct actcttaagt gagatatgaa gtattatcct tttgttcagt 1900

 tgccccgggc ttttgaacag aagagtaaat acagaattga aaaagataaa 1950

 cactcaacca aacaatgtga aaacgggttc tgtagtattt gtaaaaaggc 2000

 ccggcccagg accactgtga gctggaaaag ggagaaaggc agtgggaaaa 2050

 gaggtgagcc gaagatcaat tcgacagaca gacggtgtgt atgcccctcc 2100

 ctgtttgact tcacacacac tcataacttt ccaaatgaaa ccccacagta 2150

 tagcgcatat tttcgatatt tttgtgaatt ccaaaaggaa atcacagggc 2200

 tgttcgaaat attgggggaa cactgtgttt ctgcatcatc tgcatttgct 2250

 ccccaagcaa tgtagaggtg tttaaagggc cctctgctgg ctgagtggca 2300

 atactacaac aaacttcaag gcaagtttgg ctgaaaacag ttgacaacaa 2350

 agggccccca tacacttatc cctcaaattt taagtgatat gaaatacttg 2400

 tcatgtcttt ggccaaatca gaagatattc atcctgcttc aagtcagctt 2450

 cagaaatgtt ttaaaaggga ctttagctct ggaactcaaa atcaatttat 2500

 taagagccat attctttaaa aaaaaaagct ggataatatt atctgtaata 2550

 tttcagtcct ttacaagcca aatacatgtg tcaatgtttc tagtatttca 2600

 aagaagcaat tatgtaaagt tgttcaatgt gacataatag tattataatt 2650

 ggttaagtag cttaatgatt aggcaaacta gatgaaaaga ttaggggctt 2700

 ccacactgca tagatcacac gcacatagcc acgcatacac acacagacac 2750

 acagatgtgg ggtacactga atttcaaagc ccaaatgaat agaaacacat 2800

 tttctggcta gcagaaaaaa acaaaacaaa actgttgttt ctctttcttg 2850

 ctttgagagt gtacagtaaa agggattttt tcgaattatt tttatattat 2900

 tttagcttta attgtgctgt cgttcatgaa acagagctgc tctgcttttc 2950

 tgtcagagat ggcaagggct ttttcagcat ctcgtttatg tgtggaattt 3000

 aaaaagaata aagttttatt ccattctgaa aaaaaaaaaa aaaaa 3045

<210> 2306
<211> 265
<212> PRT
<213> Homo sapien

<400> 2306
 Met Asn Met Ser Val Leu Thr Leu Gln Glu Tyr Glu Phe Glu Lys
   1               5                  10                  15

 Gln Phe Asn Glu Asn Glu Ala Ile Gln Trp Met Gln Glu Asn Trp
                  20                  25                  30

 Lys Lys Ser Phe Leu Phe Ser Ala Leu Tyr Ala Ala Phe Ile Phe
                  35                  40                  45

 Gly Gly Arg His Leu Met Asn Lys Arg Ala Lys Phe Glu Leu Arg
                  50                  55                  60

 Lys Pro Leu Val Leu Trp Ser Leu Thr Leu Ala Val Phe Ser Ile
                  65                  70                  75

 Phe Gly Ala Leu Arg Thr Gly Ala Tyr Met Val Tyr Ile Leu Met
                  80                  85                  90

 Thr Lys Gly Leu Lys Gln Ser Val Cys Asp Gln Gly Phe Tyr Asn
                  95                 100                 105

 Gly Pro Val Ser Lys Phe Trp Ala Tyr Ala Phe Val Leu Ser Lys
                 110                 115                 120

 Ala Pro Glu Leu Gly Asp Thr Ile Phe Ile Ile Leu Arg Lys Gln
                 125                 130                 135

 Lys Leu Ile Phe Leu His Trp Tyr His His Ile Thr Val Leu Leu
                 140                 145                 150

 Tyr Ser Trp Tyr Ser Tyr Lys Asp Met Val Ala Gly Gly Gly Trp
                 155                 160                 165

 Phe Met Thr Met Asn Tyr Gly Val His Ala Val Met Tyr Ser Tyr
                 170                 175                 180

 Tyr Ala Leu Arg Ala Ala Gly Phe Arg Val Ser Arg Lys Phe Ala
                 185                 190                 195

 Met Phe Ile Thr Leu Ser Gln Ile Thr Gln Met Leu Met Gly Cys
                 200                 205                 210

 Val Val Asn Tyr Leu Val Phe Cys Trp Met Gln His Asp Gln Cys
                 215                 220                 225

 His Ser His Phe Gln Asn Ile Phe Trp Ser Ser Leu Met Tyr Leu
                 230                 235                 240

 Ser Tyr Leu Val Leu Phe Cys His Phe Phe Phe Glu Ala Tyr Ile
                 245                 250                 255

 Gly Lys Met Arg Lys Thr Thr Lys Ala Glu
                 260                 265

<210> 2307
<211> 484
<212> DNA
<213> Homo sapien

<400> 2307
 ccgttcgctc cggacaccat ggacaagttt tggtggcacg cagcctgggg 50

 actctgcctc gtgccgctga gcctggcgca gatcgatttg aatataacct 100

 gccgctttgc aggtgtattc cacgtggaga aaaatggtcg ctacagcatc 150

 tctcggacgg aggccgctga cctctgcaag gctttcaata gcaccttgcc 200

 cacaatggcc cagatggaga aagctctgag catcggattt gagacctgca 250

 gtttgcattg cagtcaacag tcgaagaagg tgtgggcaga agaaaaagct 300

 agtgatcaac agtggcaatg gagctgtgga ggacagaaag ccaagtggac 350

 tcaacggaga ggccagcaag tctcaggaaa tggtgcattt ggtgaacaag 400

 gagtcgtcag aaactccaga ccagtttatg acagctgatg agacaaggaa 450

 cctgcagaat gtggacatga agattggggt gtaa 484

<210> 2308
<211> 139
<212> PRT
<213> Homo sapien

<400> 2308
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val
   1               5                  10                  15

 Pro Leu Ser Leu Ala Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe
                  20                  25                  30

 Ala Gly Val Phe His Val Glu Lys Asn Gly Arg Tyr Ser Ile Ser
                  35                  40                  45

 Arg Thr Glu Ala Ala Asp Leu Cys Lys Ala Phe Asn Ser Thr Leu
                  50                  55                  60

 Pro Thr Met Ala Gln Met Glu Lys Ala Leu Ser Ile Gly Phe Glu
                  65                  70                  75

 Thr Cys Ser Leu His Cys Ser Gln Gln Ser Lys Lys Val Trp Ala
                  80                  85                  90

 Glu Glu Lys Ala Ser Asp Gln Gln Trp Gln Trp Ser Cys Gly Gly
                  95                 100                 105

 Gln Lys Ala Lys Trp Thr Gln Arg Arg Gly Gln Gln Val Ser Gly
                 110                 115                 120

 Asn Gly Ala Phe Gly Glu Gln Gly Val Val Arg Asn Ser Arg Pro
                 125                 130                 135

 Val Tyr Asp Ser


<210> 2309
<211> 3316
<212> DNA
<213> Homo sapien

<400> 2309
 cactctcttt ctctctccct ctggcatgca tgctgctggt aggagacccc 50

 caagtcaaca ttgcttcaga aatcctttag cactcatttc tcaggagaac 100

 ttatggcttc agaatcacag ctcggttttt aagatggaca taacctgtac 150

 gaccttctga tgggctttca actttgaact ggatgtggac acttttctct 200

 cagatgacag aattactcca acttcccctt tgcagttgct tcctttcctt 250

 gaaggtagct gtatcttatt ttctttaaaa agctttttct tccaaagcca 300

 cttgccatgc cgaccgtcat tagcgcatct gtggctccaa ggacagcggc 350

 tgagccccgg tccccagggc cagttcctca cccggcccag agcaaggcca 400

 ctgaggctgg gggtggaaac ccaagtggca tctattcagc catcatcagc 450

 cgcaattttc ctattatcgg agtgaaagag aagacattcg agcaacttca 500

 caagaaatgt ctagaaaaga aagttcttta tgtggaccct gagttcccac 550

 cggatgagac ctctctcttt tatagccaga agttccccat ccagttcgtc 600

 tggaagagac ctccggaaat ttgcgagaat ccccgattta tcattgatgg 650

 agccaacaga actgacatct gtcaaggaga gctaggggac tgctggtttc 700

 tcgcagccat tgcctgcctg accctgaacc agcaccttct tttccgagtc 750

 ataccccatg atcaaagttt catcgaaaac tacgcaggga tcttccactt 800

 ccagttctgg cgctatggag agtgggtgga cgtggttata gatgactgcc 850

 tgccaacgta caacaatcaa ctggttttca ccaagtccaa ccaccgcaat 900

 gagttctgga gtgctctgct ggagaaggct tatgctaagc tccatggttc 950

 ctacgaagct ctgaaaggtg ggaacaccac agaggccatg gaggacttca 1000

 caggaggggt ggcagagttt tttgagatca gggatgctcc tagtgacatg 1050

 tacaagatca tgaagaaagc catcgagaga ggctccctca tgggctgctc 1100

 cattgatgat ggcacgaaca tgacctatgg aacctctcct tctggtctga 1150

 acatggggga gttgattgca cggatggtaa ggaatatgga taactcactg 1200

 ctccaggact cagacctcga ccccagaggc tcagatgaaa gaccgacccg 1250

 gacaatcatt ccggttcagt atgagacaag aatggcctgc gggctggtca 1300

 gaggtcacgc ctactctgtc acggggctgg atgaggtccc gttcaaaggt 1350

 gagaaagtga agctggtgcg gctgcggaat ccgtggggcc aggtggagtg 1400

 gaacggttct tggagtgata gatggaagga ctggagcttt gtggacaaag 1450

 atgagaaggc ccgtctgcag caccaggtca ctgaggatgg agagttctgg 1500

 atgtcctatg aggatttcat ctaccatttc acaaagttgg agatctgcaa 1550

 cctcacggcc gatgctctgc agtctgacaa gcttcagacc tggacagtgt 1600

 ctgtgaacga gggccgctgg gtacggggtt gctctgccgg aggctgccgc 1650

 aacttcccag atactttctg gaccaaccct cagtaccgtc tgaagctcct 1700

 ggaggaggac gatgaccctg atgactcgga ggtgatttgc agcttcctgg 1750

 tggccctgat gcagaagaac cggcggaagg accggaagct aggggccagt 1800

 ctcttcacca ttggcttcgc catctacgag gttcccaaag agatgcacgg 1850

 gaacaagcag cacctgcaga aggacttctt cctgtacaac gcctccaagg 1900

 ccaggagcaa aacctacatc aacatgcggg aggtgtccca gcgcttccgc 1950

 ctgcctccca gcgagtacgt catcgtgccc tccacctacg agccccacca 2000

 ggagggggaa ttcatcctcc gggtcttctc tgaaaagagg aacctctctg 2050

 aggaagttga aaataccatc tccgtggatc ggccagtgaa aaagaaaaaa 2100

 accaagccca tcatcttcgt ttcggacaga gcaaacagca acaaggagct 2150

 gggtgtggac caggagtcag aggagggcaa aggcaaaaca agccctgata 2200

 agcaaaagca gtccccacag ccacagcctg gcagctctga tcaggaaagt 2250

 gaggaacagc aacaattccg gaacattttc aagcagatag caggagatga 2300

 catggagatc tgtgcagatg agctcaagaa ggtccttaac acagtcgtga 2350

 acaaacacaa ggacctgaag acacacgggt tcacactgga gtcctgccgt 2400

 agcatgattg cgctcatgga tacagatggc tctggaaagc tcaacctgca 2450

 ggagttccac cacctctgga acaagattaa ggcctggcag aaaattttca 2500

 aacactatga cacagaccag tccggcacca tcaacagcta cgagatgcga 2550

 aatgcagtca acgacgcagg attccacctc aacaaccagc tctatgacat 2600

 cattaccatg cggtacgcag acaaacacat gaacatcgac tttgacagtt 2650

 tcatctgctg cttcgttagg ctggagggca tgttcagagc ttttcatgca 2700

 tttgacaagg atggagatgg tatcatcaag ctcaacgttc tggagtggct 2750

 gcagctcacc atgtatgcct gaaccaggct ggcctcatcc aaagccatgc 2800

 aggatcactc aggatttcag tttcaccctc tatttccaaa gccatttacc 2850

 tcaaaggacc cagcagctac acccctacag gcttccaggc acctcatcag 2900

 tcatgctcct cctccatttt accccctacc catccttgat cggtcatgcc 2950

 tagcctgacc ctttagtaaa gcaatgaggt aggaagaaca aacccttgtc 3000

 cctttgccat gtggaggaaa gtgcctgcct ctggtccgag ccgcctcggt 3050

 tctgaagcga gtgctcctgc ttaccttgct ctaggctgtc tgcagaagca 3100

 cctgccggtg gcactcagca cctccttgtg ctagagccct ccatcacctt 3150

 cacgctgtcc caccatgggc caggaaccaa accagcactg ggttctactg 3200

 ctgtggggta aactaactca gtggaatagg gctggttact ttgggctgtc 3250

 caactcataa gtttggctgc attttgaaaa aagctgatct aaataaaggc 3300

 atgtgtatgg ctggtc 3316

<210> 2310
<211> 821
<212> PRT
<213> Homo sapien

<400> 2310
 Met Pro Thr Val Ile Ser Ala Ser Val Ala Pro Arg Thr Ala Ala
   1               5                  10                  15

 Glu Pro Arg Ser Pro Gly Pro Val Pro His Pro Ala Gln Ser Lys
                  20                  25                  30

 Ala Thr Glu Ala Gly Gly Gly Asn Pro Ser Gly Ile Tyr Ser Ala
                  35                  40                  45

 Ile Ile Ser Arg Asn Phe Pro Ile Ile Gly Val Lys Glu Lys Thr
                  50                  55                  60

 Phe Glu Gln Leu His Lys Lys Cys Leu Glu Lys Lys Val Leu Tyr
                  65                  70                  75

 Val Asp Pro Glu Phe Pro Pro Asp Glu Thr Ser Leu Phe Tyr Ser
                  80                  85                  90

 Gln Lys Phe Pro Ile Gln Phe Val Trp Lys Arg Pro Pro Glu Ile
                  95                 100                 105

 Cys Glu Asn Pro Arg Phe Ile Ile Asp Gly Ala Asn Arg Thr Asp
                 110                 115                 120

 Ile Cys Gln Gly Glu Leu Gly Asp Cys Trp Phe Leu Ala Ala Ile
                 125                 130                 135

 Ala Cys Leu Thr Leu Asn Gln His Leu Leu Phe Arg Val Ile Pro
                 140                 145                 150

 His Asp Gln Ser Phe Ile Glu Asn Tyr Ala Gly Ile Phe His Phe
                 155                 160                 165

 Gln Phe Trp Arg Tyr Gly Glu Trp Val Asp Val Val Ile Asp Asp
                 170                 175                 180

 Cys Leu Pro Thr Tyr Asn Asn Gln Leu Val Phe Thr Lys Ser Asn
                 185                 190                 195

 His Arg Asn Glu Phe Trp Ser Ala Leu Leu Glu Lys Ala Tyr Ala
                 200                 205                 210

 Lys Leu His Gly Ser Tyr Glu Ala Leu Lys Gly Gly Asn Thr Thr
                 215                 220                 225

 Glu Ala Met Glu Asp Phe Thr Gly Gly Val Ala Glu Phe Phe Glu
                 230                 235                 240

 Ile Arg Asp Ala Pro Ser Asp Met Tyr Lys Ile Met Lys Lys Ala
                 245                 250                 255

 Ile Glu Arg Gly Ser Leu Met Gly Cys Ser Ile Asp Asp Gly Thr
                 260                 265                 270

 Asn Met Thr Tyr Gly Thr Ser Pro Ser Gly Leu Asn Met Gly Glu
                 275                 280                 285

 Leu Ile Ala Arg Met Val Arg Asn Met Asp Asn Ser Leu Leu Gln
                 290                 295                 300

 Asp Ser Asp Leu Asp Pro Arg Gly Ser Asp Glu Arg Pro Thr Arg
                 305                 310                 315

 Thr Ile Ile Pro Val Gln Tyr Glu Thr Arg Met Ala Cys Gly Leu
                 320                 325                 330

 Val Arg Gly His Ala Tyr Ser Val Thr Gly Leu Asp Glu Val Pro
                 335                 340                 345

 Phe Lys Gly Glu Lys Val Lys Leu Val Arg Leu Arg Asn Pro Trp
                 350                 355                 360

 Gly Gln Val Glu Trp Asn Gly Ser Trp Ser Asp Arg Trp Lys Asp
                 365                 370                 375

 Trp Ser Phe Val Asp Lys Asp Glu Lys Ala Arg Leu Gln His Gln
                 380                 385                 390

 Val Thr Glu Asp Gly Glu Phe Trp Met Ser Tyr Glu Asp Phe Ile
                 395                 400                 405

 Tyr His Phe Thr Lys Leu Glu Ile Cys Asn Leu Thr Ala Asp Ala
                 410                 415                 420

 Leu Gln Ser Asp Lys Leu Gln Thr Trp Thr Val Ser Val Asn Glu
                 425                 430                 435

 Gly Arg Trp Val Arg Gly Cys Ser Ala Gly Gly Cys Arg Asn Phe
                 440                 445                 450

 Pro Asp Thr Phe Trp Thr Asn Pro Gln Tyr Arg Leu Lys Leu Leu
                 455                 460                 465

 Glu Glu Asp Asp Asp Pro Asp Asp Ser Glu Val Ile Cys Ser Phe
                 470                 475                 480

 Leu Val Ala Leu Met Gln Lys Asn Arg Arg Lys Asp Arg Lys Leu
                 485                 490                 495

 Gly Ala Ser Leu Phe Thr Ile Gly Phe Ala Ile Tyr Glu Val Pro
                 500                 505                 510

 Lys Glu Met His Gly Asn Lys Gln His Leu Gln Lys Asp Phe Phe
                 515                 520                 525

 Leu Tyr Asn Ala Ser Lys Ala Arg Ser Lys Thr Tyr Ile Asn Met
                 530                 535                 540

 Arg Glu Val Ser Gln Arg Phe Arg Leu Pro Pro Ser Glu Tyr Val
                 545                 550                 555

 Ile Val Pro Ser Thr Tyr Glu Pro His Gln Glu Gly Glu Phe Ile
                 560                 565                 570

 Leu Arg Val Phe Ser Glu Lys Arg Asn Leu Ser Glu Glu Val Glu
                 575                 580                 585

 Asn Thr Ile Ser Val Asp Arg Pro Val Lys Lys Lys Lys Thr Lys
                 590                 595                 600

 Pro Ile Ile Phe Val Ser Asp Arg Ala Asn Ser Asn Lys Glu Leu
                 605                 610                 615

 Gly Val Asp Gln Glu Ser Glu Glu Gly Lys Gly Lys Thr Ser Pro
                 620                 625                 630

 Asp Lys Gln Lys Gln Ser Pro Gln Pro Gln Pro Gly Ser Ser Asp
                 635                 640                 645

 Gln Glu Ser Glu Glu Gln Gln Gln Phe Arg Asn Ile Phe Lys Gln
                 650                 655                 660

 Ile Ala Gly Asp Asp Met Glu Ile Cys Ala Asp Glu Leu Lys Lys
                 665                 670                 675

 Val Leu Asn Thr Val Val Asn Lys His Lys Asp Leu Lys Thr His
                 680                 685                 690

 Gly Phe Thr Leu Glu Ser Cys Arg Ser Met Ile Ala Leu Met Asp
                 695                 700                 705

 Thr Asp Gly Ser Gly Lys Leu Asn Leu Gln Glu Phe His His Leu
                 710                 715                 720

 Trp Asn Lys Ile Lys Ala Trp Gln Lys Ile Phe Lys His Tyr Asp
                 725                 730                 735

 Thr Asp Gln Ser Gly Thr Ile Asn Ser Tyr Glu Met Arg Asn Ala
                 740                 745                 750

 Val Asn Asp Ala Gly Phe His Leu Asn Asn Gln Leu Tyr Asp Ile
                 755                 760                 765

 Ile Thr Met Arg Tyr Ala Asp Lys His Met Asn Ile Asp Phe Asp
                 770                 775                 780

 Ser Phe Ile Cys Cys Phe Val Arg Leu Glu Gly Met Phe Arg Ala
                 785                 790                 795

 Phe His Ala Phe Asp Lys Asp Gly Asp Gly Ile Ile Lys Leu Asn
                 800                 805                 810

 Val Leu Glu Trp Leu Gln Leu Thr Met Tyr Ala
                 815                 820

<210> 2311
<211> 1638
<212> DNA
<213> Homo sapien

<400> 2311
 tcagcgggag gggctggacc ccgcgttcct cctccctgcc ggtccccatc 50

 cttaaagcga gagtctggac gccccgcctg tgggagagag cgccgggatc 100

 cggacgggga gcaaccgggg caggccgtgc cggctgagga ggtcctgagg 150

 ctacagagct gccgcggctg gcacacgagc gcctcggcac taaccgagtg 200

 ttcgcggggg ctgtgagggg agggccccgg gcgccattgc tggcggtggg 250

 agcgccgccc ggtctcagcc cgccctcggc tgctctcctc ctccggctgg 300

 gaggggccgt agctcggggc cgtcgccagc cccggcccgg gctcgagaat 350

 caagggcctc ggccgccgtc ccgcagctca gtccatcgcc cttgccgggc 400

 agcccgggca gagaccatgt ttgacaagac gcggctgccg tacgtggccc 450

 tcgatgtgct ctgcgtgttg ctggctggat tgccttttgc aattcttact 500

 tcaaggcata cccccttcca acgaggagta ttctgtaatg atgagtccat 550

 caagtaccct tacaaagaag acaccatacc ttatgcgtta ttaggtggaa 600

 taatcattcc attcagtatt atcgttatta ttcttggaga aaccctgtct 650

 gtttactgta accttttgca ctcaaattcc tttatcagga ataactacat 700

 agccactatt tacaaagcca ttggaacctt tttatttggt gcagctgcta 750

 gtcagtccct gactgacatt gccaagtatt caataggcag actgcggcct 800

 cacttcttgg atgtttgtga tccagattgg tcaaaaatca actgcagcga 850

 tggttacatt gaatactaca tatgtcgagg gaatgcagaa agagttaagg 900

 aaggcaggtt gtccttctat tcaggccact cttcgttttc catgtactgc 950

 atgctgtttg tggcacttta tcttcaagcc aggatgaagg gagactgggc 1000

 aagactctta cgccccacac tgcaatttgg tcttgttgcc gtatccattt 1050

 atgtgggcct ttctcgagtt tctgattata aacaccactg gagcgatgtg 1100

 ttgactggac tcattcaggg agctctggtt gcaatattag ttgctgtata 1150

 tgtatcggat ttcttcaaag aaagaacttc ttttaaagaa agaaaagagg 1200

 aggactctca tacaactctg catgaaacac caacaactgg gaatcactat 1250

 ccgagcaatc accagccttg aaaggcagca gggtgcccag gtgaagctgg 1300

 cctgttttct aaaggaaaat gattgccaca aggcaagagg atgcatcttt 1350

 cttcctggtg tacaagcctt taaagacttc tgctgctgct atgcctcttg 1400

 gatgcacact ttgtgtgtac atagttacct ttaactcagt ggttatctaa 1450

 tagctctaaa ctcattaaaa aaactccaag ccttccacca aaacagtgcc 1500

 ccacctgtat acatttttat taaaaaaatg taatgcttat gtataaacat 1550

 gtatgtaata tgctttctat gaatgatgtt tgatttaaat ataatacata 1600

 ttaaaatgta tgggagaacc aaaaaaaaaa aaaaaaaa 1638

<210> 2312
<211> 284
<212> PRT
<213> Homo sapien

<400> 2312
 Met Phe Asp Lys Thr Arg Leu Pro Tyr Val Ala Leu Asp Val Leu
   1               5                  10                  15

 Cys Val Leu Leu Ala Gly Leu Pro Phe Ala Ile Leu Thr Ser Arg
                  20                  25                  30

 His Thr Pro Phe Gln Arg Gly Val Phe Cys Asn Asp Glu Ser Ile
                  35                  40                  45

 Lys Tyr Pro Tyr Lys Glu Asp Thr Ile Pro Tyr Ala Leu Leu Gly
                  50                  55                  60

 Gly Ile Ile Ile Pro Phe Ser Ile Ile Val Ile Ile Leu Gly Glu
                  65                  70                  75

 Thr Leu Ser Val Tyr Cys Asn Leu Leu His Ser Asn Ser Phe Ile
                  80                  85                  90

 Arg Asn Asn Tyr Ile Ala Thr Ile Tyr Lys Ala Ile Gly Thr Phe
                  95                 100                 105

 Leu Phe Gly Ala Ala Ala Ser Gln Ser Leu Thr Asp Ile Ala Lys
                 110                 115                 120

 Tyr Ser Ile Gly Arg Leu Arg Pro His Phe Leu Asp Val Cys Asp
                 125                 130                 135

 Pro Asp Trp Ser Lys Ile Asn Cys Ser Asp Gly Tyr Ile Glu Tyr
                 140                 145                 150

 Tyr Ile Cys Arg Gly Asn Ala Glu Arg Val Lys Glu Gly Arg Leu
                 155                 160                 165

 Ser Phe Tyr Ser Gly His Ser Ser Phe Ser Met Tyr Cys Met Leu
                 170                 175                 180

 Phe Val Ala Leu Tyr Leu Gln Ala Arg Met Lys Gly Asp Trp Ala
                 185                 190                 195

 Arg Leu Leu Arg Pro Thr Leu Gln Phe Gly Leu Val Ala Val Ser
                 200                 205                 210

 Ile Tyr Val Gly Leu Ser Arg Val Ser Asp Tyr Lys His His Trp
                 215                 220                 225

 Ser Asp Val Leu Thr Gly Leu Ile Gln Gly Ala Leu Val Ala Ile
                 230                 235                 240

 Leu Val Ala Val Tyr Val Ser Asp Phe Phe Lys Glu Arg Thr Ser
                 245                 250                 255

 Phe Lys Glu Arg Lys Glu Glu Asp Ser His Thr Thr Leu His Glu
                 260                 265                 270

 Thr Pro Thr Thr Gly Asn His Tyr Pro Ser Asn His Gln Pro
                 275                 280

<210> 2313
<211> 1280
<212> DNA
<213> Homo sapien

<400> 2313
 atgccccaac tttccggagg aggtggcggc ggcggggggg acccggaact 50

 ctgcgccacg gacgagatga tccccttcaa ggacgagggc gatcctcaga 100

 aggaaaagat cttcgccgag atcagtcatc ccgaagagga aggcgattta 150

 gctgacatca agtcttcctt ggtgaacgag tctgaaatca tcccggccag 200

 caacggacac gaggtggcca gacaagcaca aacctctcag gagccctacc 250

 acgacaaggc cagagaacac cccgatgacg gaaagcatcc agatggaggc 300

 ctctacaaca agggaccctc ctactcgagt tattccgggt acataatgat 350

 gccaaatatg aataacgacc catacatgtc aaatggatct ctttctccac 400

 ccatcccgag aacatcaaat aaagtgcccg tggtgcagcc atcccatgcg 450

 gtccatcctc tcacccccct catcacttac agtgacgagc acttttctcc 500

 agggtcacac ccgtcacaca tcccatcaga tgtcaactcc aaacaaggca 550

 tgtccagaca tcctccagct cctgatatcc ctactttcta tcccttgtct 600

 ccgggtggtg ttggacagat caccccacct cttggttggc aaggtcagcc 650

 tgtatatccc atcacgggtg gattcaggca accctaccca tcctcactgt 700

 cagtcgacac ttccatgtcc aggttttccc atcatatgat tcccggtcct 750

 cctggtcccc acacaactgg catccctcat ccagctattg taacacctca 800

 ggtcaaacag gaacatcccc acactgacag tgacctaatg cacgtgtgct 850

 ctgcttttct cctcccccat cccttcctca ttccttcaac cccttcccct 900

 aaccaccacc accaccacct tttaggaagc ctcagcatga acagagaaag 950

 gagcaggagc caaaaagacc tcacattaag aagcctctga atgcttttat 1000

 gttatacatg aaagaaatga gagcgaatgt cgttgctgag tgtactctaa 1050

 aagaaagtgc agctatcaac cagattcttg gcagaaggtg gcatgccctc 1100

 tcccgtgaag agcaggctaa atattatgaa ttagcacgga aagaaagaca 1150

 gctacatatg cagctttatc caggctggtc tgcaagagac aattatggta 1200

 agaaaaagaa gaggaagaga gagaaactac aggaatctgc atcaggtaca 1250

 ggtccaagaa tgacagctgc ctacatctga 1280

<210> 2314
<211> 329
<212> PRT
<213> Homo sapien

<400> 2314
 Met Pro Gln Leu Ser Gly Gly Gly Gly Gly Gly Gly Gly Asp Pro
   1               5                  10                  15

 Glu Leu Cys Ala Thr Asp Glu Met Ile Pro Phe Lys Asp Glu Gly
                  20                  25                  30

 Asp Pro Gln Lys Glu Lys Ile Phe Ala Glu Ile Ser His Pro Glu
                  35                  40                  45

 Glu Glu Gly Asp Leu Ala Asp Ile Lys Ser Ser Leu Val Asn Glu
                  50                  55                  60

 Ser Glu Ile Ile Pro Ala Ser Asn Gly His Glu Val Ala Arg Gln
                  65                  70                  75

 Ala Gln Thr Ser Gln Glu Pro Tyr His Asp Lys Ala Arg Glu His
                  80                  85                  90

 Pro Asp Asp Gly Lys His Pro Asp Gly Gly Leu Tyr Asn Lys Gly
                  95                 100                 105

 Pro Ser Tyr Ser Ser Tyr Ser Gly Tyr Ile Met Met Pro Asn Met
                 110                 115                 120

 Asn Asn Asp Pro Tyr Met Ser Asn Gly Ser Leu Ser Pro Pro Ile
                 125                 130                 135

 Pro Arg Thr Ser Asn Lys Val Pro Val Val Gln Pro Ser His Ala
                 140                 145                 150

 Val His Pro Leu Thr Pro Leu Ile Thr Tyr Ser Asp Glu His Phe
                 155                 160                 165

 Ser Pro Gly Ser His Pro Ser His Ile Pro Ser Asp Val Asn Ser
                 170                 175                 180

 Lys Gln Gly Met Ser Arg His Pro Pro Ala Pro Asp Ile Pro Thr
                 185                 190                 195

 Phe Tyr Pro Leu Ser Pro Gly Gly Val Gly Gln Ile Thr Pro Pro
                 200                 205                 210

 Leu Gly Trp Gln Gly Gln Pro Val Tyr Pro Ile Thr Gly Gly Phe
                 215                 220                 225

 Arg Gln Pro Tyr Pro Ser Ser Leu Ser Val Asp Thr Ser Met Ser
                 230                 235                 240

 Arg Phe Ser His His Met Ile Pro Gly Pro Pro Gly Pro His Thr
                 245                 250                 255

 Thr Gly Ile Pro His Pro Ala Ile Val Thr Pro Gln Val Lys Gln
                 260                 265                 270

 Glu His Pro His Thr Asp Ser Asp Leu Met His Val Cys Ser Ala
                 275                 280                 285

 Phe Leu Leu Pro His Pro Phe Leu Ile Pro Ser Thr Pro Ser Pro
                 290                 295                 300

 Asn His His His His His Leu Leu Gly Ser Leu Ser Met Asn Arg
                 305                 310                 315

 Glu Arg Ser Arg Ser Gln Lys Asp Leu Thr Leu Arg Ser Leu
                 320                 325

<210> 2315
<211> 1649
<212> DNA
<213> Homo sapien

<400> 2315
 agaggtgaga gagtcgcgcc cgggagtccg ccgcctgcgc caggatggag 50

 ttcgtgaaat gccttggcca ccccgaagag ttctacaacc tggtgcgctt 100

 ccggatcggg ggcaagcgga aggtgatgcc caagatggac caggactcgc 150

 tcagcagcag cctgaaaact tgctacaagt atctcaatca gaccagtcgc 200

 agtttcgcag ctgttatcca ggcgctggat ggggaaatgc gcaacgcagt 250

 gtgcatattt tatctggttc tccgagctct ggacacactg gaagatgaca 300

 tgaccatcag tgtggaaaag aaggtcccgc tgttacacaa ctttcactct 350

 ttcctttacc aaccagactg gcggttcatg gagagcaagg agaaggatcg 400

 ccaggtgctg gaggacttcc caacgatctc ccttgagttt agaaatctgg 450

 ctgagaaata ccaaacagtg attgccgaca tttgccggag aatgggcatt 500

 gggatggcag agtttttgga taagcatgtg acctctgaac aggagtggga 550

 caagtactgc cactatgttg ctgggctggt cggaattggc ctttcccgtc 600

 ttttctcagc ctcagagttt gaagacccct tagttggtga agatacagaa 650

 cgtgccaact ctatgggcct gtttctgcag aaaacaaaca tcatccgtga 700

 ctatctggaa gaccagcaag gaggaagaga gttctggcct caagaggttt 750

 ggagcaggta tgttaagaag ttaggggatt ttgctaagcc ggagaatatt 800

 gacttggccg tgcagtgcct gaatgaactt ataaccaatg cactgcacca 850

 catcccagat gtcatcacct acctttcgag actcagaaac cagagtgtgt 900

 ttaacttctg tgctattcca caggtgatgg ccattgccac tttggctgcc 950

 tgttataata accagcaggt gttcaaaggg gcagtgaaga ttcggaaagg 1000

 gcaagcagtg acccttatga tggatgccac caatatgcca gctgtcaaag 1050

 ccatcatata tcagtatatg gaagagattt atcatagaat ccccgactca 1100

 gacccatctt ctagcaaaac aaggcagatc atctccacca tccggacgca 1150

 gaatcttccc aactgtcagc tgatttcccg aagccactac tcccccatct 1200

 acctgtcgtt tgtcatgctt ttggctgccc tgagctggca gtacctgacc 1250

 actctctccc aggtaacaga agactatgtt cagactggag aacactgatc 1300

 ccaaatttgt ccatagctga agtccaccat aaagtggatt tacttttttt 1350

 ctttaaggat ggatgttgtg ttctctttat ttttttccta ctactttaat 1400

 ccctaaaaga acgctgtgtg gctgggacct ttaggaaagt gaaatgcagg 1450

 tgagaagaac ctaaacataa aaggaaaggg tgcctcatcc cagcaacctg 1500

 tccttgtggg tgatgatcac tgtgctgctt gcggctcatg gcagagcatt 1550

 cagtgccacg gtttaggtga agtcgctgca tatgtgactg tcatgagatc 1600

 ctacttagta tgatcctggc tagaatgata attaaaagta tttaatttg 1649

<210> 2316
<211> 417
<212> PRT
<213> Homo sapien

<400> 2316
 Met Glu Phe Val Lys Cys Leu Gly His Pro Glu Glu Phe Tyr Asn
   1               5                  10                  15

 Leu Val Arg Phe Arg Ile Gly Gly Lys Arg Lys Val Met Pro Lys
                  20                  25                  30

 Met Asp Gln Asp Ser Leu Ser Ser Ser Leu Lys Thr Cys Tyr Lys
                  35                  40                  45

 Tyr Leu Asn Gln Thr Ser Arg Ser Phe Ala Ala Val Ile Gln Ala
                  50                  55                  60

 Leu Asp Gly Glu Met Arg Asn Ala Val Cys Ile Phe Tyr Leu Val
                  65                  70                  75

 Leu Arg Ala Leu Asp Thr Leu Glu Asp Asp Met Thr Ile Ser Val
                  80                  85                  90

 Glu Lys Lys Val Pro Leu Leu His Asn Phe His Ser Phe Leu Tyr
                  95                 100                 105

 Gln Pro Asp Trp Arg Phe Met Glu Ser Lys Glu Lys Asp Arg Gln
                 110                 115                 120

 Val Leu Glu Asp Phe Pro Thr Ile Ser Leu Glu Phe Arg Asn Leu
                 125                 130                 135

 Ala Glu Lys Tyr Gln Thr Val Ile Ala Asp Ile Cys Arg Arg Met
                 140                 145                 150

 Gly Ile Gly Met Ala Glu Phe Leu Asp Lys His Val Thr Ser Glu
                 155                 160                 165

 Gln Glu Trp Asp Lys Tyr Cys His Tyr Val Ala Gly Leu Val Gly
                 170                 175                 180

 Ile Gly Leu Ser Arg Leu Phe Ser Ala Ser Glu Phe Glu Asp Pro
                 185                 190                 195

 Leu Val Gly Glu Asp Thr Glu Arg Ala Asn Ser Met Gly Leu Phe
                 200                 205                 210

 Leu Gln Lys Thr Asn Ile Ile Arg Asp Tyr Leu Glu Asp Gln Gln
                 215                 220                 225

 Gly Gly Arg Glu Phe Trp Pro Gln Glu Val Trp Ser Arg Tyr Val
                 230                 235                 240

 Lys Lys Leu Gly Asp Phe Ala Lys Pro Glu Asn Ile Asp Leu Ala
                 245                 250                 255

 Val Gln Cys Leu Asn Glu Leu Ile Thr Asn Ala Leu His His Ile
                 260                 265                 270

 Pro Asp Val Ile Thr Tyr Leu Ser Arg Leu Arg Asn Gln Ser Val
                 275                 280                 285

 Phe Asn Phe Cys Ala Ile Pro Gln Val Met Ala Ile Ala Thr Leu
                 290                 295                 300

 Ala Ala Cys Tyr Asn Asn Gln Gln Val Phe Lys Gly Ala Val Lys
                 305                 310                 315

 Ile Arg Lys Gly Gln Ala Val Thr Leu Met Met Asp Ala Thr Asn
                 320                 325                 330

 Met Pro Ala Val Lys Ala Ile Ile Tyr Gln Tyr Met Glu Glu Ile
                 335                 340                 345

 Tyr His Arg Ile Pro Asp Ser Asp Pro Ser Ser Ser Lys Thr Arg
                 350                 355                 360

 Gln Ile Ile Ser Thr Ile Arg Thr Gln Asn Leu Pro Asn Cys Gln
                 365                 370                 375

 Leu Ile Ser Arg Ser His Tyr Ser Pro Ile Tyr Leu Ser Phe Val
                 380                 385                 390

 Met Leu Leu Ala Ala Leu Ser Trp Gln Tyr Leu Thr Thr Leu Ser
                 395                 400                 405

 Gln Val Thr Glu Asp Tyr Val Gln Thr Gly Glu His
                 410                 415

<210> 2317
<211> 2496
<212> DNA
<213> Homo sapien

<400> 2317
 gttttgaaag ttgatggagc gaactgcttt tccaaagact cttttgaaaa 50

 actttttaag taggccattc tgactttaac atttctcttt gtcttaacat 100

 tagacaaaaa gtaaccttcc tgaagaggac atgtgattgg aagttgtcaa 150

 ttgttgaagc attggtaact ccagtctcta acgttttaga aaatcataac 200

 aagcggttct ctaccctgta aaggtgaact actgagttct tcattatgtc 250

 tgatggagat tatgattacc tcatcaagtt tttagctttg ggagactctg 300

 gtgtagggaa gaccagtgta ctttaccaat atacagatgg taaatttaac 350

 tccaaattta tcacaacagt gggcattgat ttcagggaaa aaagagtggt 400

 gtacagagcc agtgggccgg atggagccac tggcagaggc cagagaatcc 450

 acctgcagtt atgggacaca gcagggcagg agaggtttcg tagcttaacg 500

 acagcgttct tcagagatgc tatgggtttt cttctacttt ttgatctgac 550

 aaatgagcaa agtttcctca atgtcagaaa ctggataagc cagctacaga 600

 tgcatgcata ttgtgaaaac ccagatatag tgctgtgtgg aaacaagagt 650

 gatctggagg accagagagt agtgaaagag gaggaagcca tagcactcgc 700

 agagaaatat ggaatcccct actttgaaac tagtgctgcc aatgggacaa 750

 acataagcca agcaattgag atgcttctgg acctgataat gaagcgaatg 800

 gaacggtgtg tggacaagtc ctggattcct gaaggagtgg tgcgatcaaa 850

 tggtcatgcc tctacggatc agttaagtga agaaaaggag aaaggggcat 900

 gtggctgttg agaagtcaag taagtgacat agtagttcag gtggcccatg 950

 cctgggatct tctctatgat tgatacatgg cacagtgaga gattaatggg 1000

 cattgtgtac aaattgcttc tcaccatccc cattagacct acgaataaag 1050

 catccggttc taaaattaat ttgttgcagc tttgtaaata tttctttaag 1100

 attcagcctg agagttagga gaaatatttc agagccaaaa gtgccttata 1150

 caaccttagc ctattatagt aaatcattca aggattcaga attttgcagt 1200

 cacagaagag tgtatttatt atgtagaatg aatgagggta ctgtcacctg 1250

 ccttaatgta ggtaggccca gagtcttaca tttaagatct tacatgcagt 1300

 tataaaaccg ccacagtctt caatccagat ttgaagactc atgccatagg 1350

 tgacattcta aaataccatt aaagccactt aaatgttaaa taagaatata 1400

 catgcacatc agctcaatgt ctttgagtat taattttatg taagcattct 1450

 atttaacatg aatataggac aaatcatggc tatatctata gaccttggat 1500

 aaactggatt gaccaattat acactcacgg tgactttttt attggtggga 1550

 aggggattgg ggtggggcag gctggcttaa tgtaatatga gcaaccaaag 1600

 tgggacttct gtctccccgc tatattccca ttgctctgaa tggttgattg 1650

 aagggtcagg gaactagatt ttatggcttt agttcactgt gattgtacat 1700

 ttatacttgg cctatgtgct ggccgcacct gaacatagct ggtgcttatg 1750

 ccgagttatt tgtgatgagt aaatatttag tttctttttc ttcatattta 1800

 taatgttgat ctggcatcct caggctgcag ctttattagc ttataaatta 1850

 ctcatctctg tctttaccag caggctctgt attgttgata tttgcaactt 1900

 gttttgcttt tccattggtg gaattgaaat aattagtttt taattacata 1950

 agatgcctgt ttgctatttg gtggaagata gatgttcata ttgaagcagt 2000

 cacatttgta ctgtagttca ataaaagaaa aatgaagtat tctgtagcct 2050

 atatttttca tagagctcat gagcatttac tgtacttgct gggtcttgcc 2100

 aagatcattt attccgctgc attgccaaag tgtcttcata ccaaattaaa 2150

 ggtggtttta atatatgttt catggaagtt gtttataaaa ttcaaaggta 2200

 tttcatttag gtgaaaagtc ttatttatta aagtggtttg aataaagtag 2250

 atcaaaactt ccagagatct taatggctat ataggaagaa atatcactca 2300

 ccataattta aataaagaat aaaaatacat gtattttatg gtggcaaatg 2350

 tttggtagaa ctgtaattag aaaaatacaa gtatatttgc gtgatggtta 2400

 cactagaagc ccagacttta cgactacaca atatattcat gtatctaaac 2450

 tgtacttgta ccccctaaat ttatttttaa aaaaaaaaaa aaaaaa 2496

<210> 2318
<211> 221
<212> PRT
<213> Homo sapien

<400> 2318
 Met Ser Asp Gly Asp Tyr Asp Tyr Leu Ile Lys Phe Leu Ala Leu
   1               5                  10                  15

 Gly Asp Ser Gly Val Gly Lys Thr Ser Val Leu Tyr Gln Tyr Thr
                  20                  25                  30

 Asp Gly Lys Phe Asn Ser Lys Phe Ile Thr Thr Val Gly Ile Asp
                  35                  40                  45

 Phe Arg Glu Lys Arg Val Val Tyr Arg Ala Ser Gly Pro Asp Gly
                  50                  55                  60

 Ala Thr Gly Arg Gly Gln Arg Ile His Leu Gln Leu Trp Asp Thr
                  65                  70                  75

 Ala Gly Gln Glu Arg Phe Arg Ser Leu Thr Thr Ala Phe Phe Arg
                  80                  85                  90

 Asp Ala Met Gly Phe Leu Leu Leu Phe Asp Leu Thr Asn Glu Gln
                  95                 100                 105

 Ser Phe Leu Asn Val Arg Asn Trp Ile Ser Gln Leu Gln Met His
                 110                 115                 120

 Ala Tyr Cys Glu Asn Pro Asp Ile Val Leu Cys Gly Asn Lys Ser
                 125                 130                 135

 Asp Leu Glu Asp Gln Arg Val Val Lys Glu Glu Glu Ala Ile Ala
                 140                 145                 150

 Leu Ala Glu Lys Tyr Gly Ile Pro Tyr Phe Glu Thr Ser Ala Ala
                 155                 160                 165

 Asn Gly Thr Asn Ile Ser Gln Ala Ile Glu Met Leu Leu Asp Leu
                 170                 175                 180

 Ile Met Lys Arg Met Glu Arg Cys Val Asp Lys Ser Trp Ile Pro
                 185                 190                 195

 Glu Gly Val Val Arg Ser Asn Gly His Ala Ser Thr Asp Gln Leu
                 200                 205                 210

 Ser Glu Glu Lys Glu Lys Gly Ala Cys Gly Cys
                 215                 220

<210> 2319
<211> 2776
<212> DNA
<213> Homo sapien

<400> 2319
 gcggccgcgt cgaccggagg tgcctgttta cccgcgccgg actcaccgcc 50

 gccgccgccg cgggatccga gtgcgggcgc gggcgcgggc gctcccggcg 100

 agccacggtg gtgctggcta gagtgtttac gtttggaccc aagcttaact 150

 tttccaatgt ggaatcctgg gccttcattg gttccgatgt cataggaatc 200

 tacgctagag ggcttcctgt gtgccgggca ctgtggtttt tggaagaagc 250

 tgaccgcctg aaaagaaatt ataaaacatg aaaatcgctt tgaggtgacc 300

 aagtccagag gcccctaact cctcccaagc tggatctggg gtgtaagaac 350

 tgtgacttca gatcatccaa tggcagacca gagaatggac atttcttcaa 400

 ccatcagtga tttcatgtcc ccgggcccca ccgacctgct ttccagctct 450

 cttggtacca gtggtgtgga ttgcaaccgc aaacggaaag gcagctccac 500

 tgactaccaa gaaagcatgg acacagacaa agatgaccct catggaaggt 550

 tagaatatac agaacaccaa ggaaggataa aaaatgcaag ggaagctcac 600

 agtcagattg aaaagcggcg tcgggataaa atgaacagtt ttatagatga 650

 attggcttct ttggtaccaa catgcaacgc aatgtccagg aaattagata 700

 aacttactgt gctaaggatg gctgttcagc acatgaaaac attaagaggt 750

 gccaccaatc catacacaga agcaaactac aaaccaactt ttctatcaga 800

 cgatgaattg aaacacctca ttctcagggc agcagatgga tttttgtttg 850

 tcgtaggatg tgaccgaggg aagatactct ttgtctcaga gtctgtcttc 900

 aagatcctca actacagcca gaatgatctg attggtcaga gtttgtttga 950

 ctacctgcat cctaaagata ttgccaaagt caaggagcag ctctcctcct 1000

 ctgacaccgc accccgggag cggctcatag atgcaaaaac tggacttcca 1050

 gttaaaacag atataacccc tgggccatct cgattatgtt ctggagcacg 1100

 acgttctttc ttctgtagga tgaagtgtaa caggccttca gtaaaggttg 1150

 aagacaagga cttcccctct acctgctcaa agaaaaaagc agatcgaaaa 1200

 agcttctgca caatccacag cacaggctat ttgaaaagct ggccacccac 1250

 aaagatgggg ctggatgaag acaacgaacc agacaatgag gggtgtaacc 1300

 tcagctgcct cgtcgcaatt ggacgactgc attctcatgt agttccacaa 1350

 ccagtgaacg gggaaatcag ggtgaaatct atggaatatg tttctcggca 1400

 cgcgatagat ggaaagtttg tttttgtaga ccagagggca acagctattt 1450

 tggcatattt accacaagaa cttctaggca catcgtgtta tgaatatttt 1500

 caccaagatg acataggaca tcttgcagaa tgtcataggc aagttttaca 1550

 gacgagagaa aaaattacaa ctaattgcta taaatttaaa atcaaagatg 1600

 gttcttttat cacactacgg agtcgatggt tcagtttcat gaacccttgg 1650

 accaaggaag tagaatatat tgtctcaact aacactgttg ttttagccaa 1700

 cgtcctggaa ggcggggacc caaccttccc acagctcaca gcatcccccc 1750

 acagcatgga cagcatgctg ccctctggag aaggtggccc aaagaggacc 1800

 caccccactg ttccagggat tccaggggga acccgggctg gggcaggaaa 1850

 aataggccga atgattgctg aggaaatcat ggaaatccac aggataagag 1900

 ggtcatcgcc ttctagctgt ggctccagcc cattgaacat cacgagtacg 1950

 cctccccctg atgcctcttc tccaggaggc aagaagattt taaatggagg 2000

 gactccagac attccttcca gtggcctact atcaggccag gctcaggaga 2050

 acccaggtta tccatattct gatagttctt ctattcttgg tgagaacccc 2100

 cacataggta tagacatgat tgacaacgac caaggatcaa gtagtcccag 2150

 taatgatgag gcagcaatgg ctgtcatcat gagcctcttg gaagcagatg 2200

 ctggactggg tggccctgtt gactttagtg acttgccatg gccgctgtaa 2250

 acactacatg ttgctttggc aacagctata gtatcaaagt gcattactgg 2300

 tggagtttta cagtctgtga agcttactgg ataaggagag aatagctttt 2350

 atgtactgac ttcataaaag ccatctcaga gccattgata caagtcaatc 2400

 ttactatatg taacttcaga caaagtggaa ctaagcctgc tccagtgttt 2450

 cctcatcatt gattattggg ctagctgtgg atagcttgca ttaattgtat 2500

 attttggatt ctgtttgtgt tgaatttttt aatcattgtg cacagaagca 2550

 tcattggtag cttttatatg caaatggtca tttcagatgt atggtgtttt 2600

 tacactacaa agaagtcccc catgtggata tttcttatac taattgtatc 2650

 ataaagccgt ttattcttcc ttgtaagaat cctttactat aaatatgggt 2700

 taaagtataa tgtactagac agttaaatat ttttaataaa tgtttccctt 2750

 gttctataaa aaaaaaaaaa aaaaaa 2776

<210> 2320
<211> 626
<212> PRT
<213> Homo sapien

<400> 2320
 Met Ala Asp Gln Arg Met Asp Ile Ser Ser Thr Ile Ser Asp Phe
   1               5                  10                  15

 Met Ser Pro Gly Pro Thr Asp Leu Leu Ser Ser Ser Leu Gly Thr
                  20                  25                  30

 Ser Gly Val Asp Cys Asn Arg Lys Arg Lys Gly Ser Ser Thr Asp
                  35                  40                  45

 Tyr Gln Glu Ser Met Asp Thr Asp Lys Asp Asp Pro His Gly Arg
                  50                  55                  60

 Leu Glu Tyr Thr Glu His Gln Gly Arg Ile Lys Asn Ala Arg Glu
                  65                  70                  75

 Ala His Ser Gln Ile Glu Lys Arg Arg Arg Asp Lys Met Asn Ser
                  80                  85                  90

 Phe Ile Asp Glu Leu Ala Ser Leu Val Pro Thr Cys Asn Ala Met
                  95                 100                 105

 Ser Arg Lys Leu Asp Lys Leu Thr Val Leu Arg Met Ala Val Gln
                 110                 115                 120

 His Met Lys Thr Leu Arg Gly Ala Thr Asn Pro Tyr Thr Glu Ala
                 125                 130                 135

 Asn Tyr Lys Pro Thr Phe Leu Ser Asp Asp Glu Leu Lys His Leu
                 140                 145                 150

 Ile Leu Arg Ala Ala Asp Gly Phe Leu Phe Val Val Gly Cys Asp
                 155                 160                 165

 Arg Gly Lys Ile Leu Phe Val Ser Glu Ser Val Phe Lys Ile Leu
                 170                 175                 180

 Asn Tyr Ser Gln Asn Asp Leu Ile Gly Gln Ser Leu Phe Asp Tyr
                 185                 190                 195

 Leu His Pro Lys Asp Ile Ala Lys Val Lys Glu Gln Leu Ser Ser
                 200                 205                 210

 Ser Asp Thr Ala Pro Arg Glu Arg Leu Ile Asp Ala Lys Thr Gly
                 215                 220                 225

 Leu Pro Val Lys Thr Asp Ile Thr Pro Gly Pro Ser Arg Leu Cys
                 230                 235                 240

 Ser Gly Ala Arg Arg Ser Phe Phe Cys Arg Met Lys Cys Asn Arg
                 245                 250                 255

 Pro Ser Val Lys Val Glu Asp Lys Asp Phe Pro Ser Thr Cys Ser
                 260                 265                 270

 Lys Lys Lys Ala Asp Arg Lys Ser Phe Cys Thr Ile His Ser Thr
                 275                 280                 285

 Gly Tyr Leu Lys Ser Trp Pro Pro Thr Lys Met Gly Leu Asp Glu
                 290                 295                 300

 Asp Asn Glu Pro Asp Asn Glu Gly Cys Asn Leu Ser Cys Leu Val
                 305                 310                 315

 Ala Ile Gly Arg Leu His Ser His Val Val Pro Gln Pro Val Asn
                 320                 325                 330

 Gly Glu Ile Arg Val Lys Ser Met Glu Tyr Val Ser Arg His Ala
                 335                 340                 345

 Ile Asp Gly Lys Phe Val Phe Val Asp Gln Arg Ala Thr Ala Ile
                 350                 355                 360

 Leu Ala Tyr Leu Pro Gln Glu Leu Leu Gly Thr Ser Cys Tyr Glu
                 365                 370                 375

 Tyr Phe His Gln Asp Asp Ile Gly His Leu Ala Glu Cys His Arg
                 380                 385                 390

 Gln Val Leu Gln Thr Arg Glu Lys Ile Thr Thr Asn Cys Tyr Lys
                 395                 400                 405

 Phe Lys Ile Lys Asp Gly Ser Phe Ile Thr Leu Arg Ser Arg Trp
                 410                 415                 420

 Phe Ser Phe Met Asn Pro Trp Thr Lys Glu Val Glu Tyr Ile Val
                 425                 430                 435

 Ser Thr Asn Thr Val Val Leu Ala Asn Val Leu Glu Gly Gly Asp
                 440                 445                 450

 Pro Thr Phe Pro Gln Leu Thr Ala Ser Pro His Ser Met Asp Ser
                 455                 460                 465

 Met Leu Pro Ser Gly Glu Gly Gly Pro Lys Arg Thr His Pro Thr
                 470                 475                 480

 Val Pro Gly Ile Pro Gly Gly Thr Arg Ala Gly Ala Gly Lys Ile
                 485                 490                 495

 Gly Arg Met Ile Ala Glu Glu Ile Met Glu Ile His Arg Ile Arg
                 500                 505                 510

 Gly Ser Ser Pro Ser Ser Cys Gly Ser Ser Pro Leu Asn Ile Thr
                 515                 520                 525

 Ser Thr Pro Pro Pro Asp Ala Ser Ser Pro Gly Gly Lys Lys Ile
                 530                 535                 540

 Leu Asn Gly Gly Thr Pro Asp Ile Pro Ser Ser Gly Leu Leu Ser
                 545                 550                 555

 Gly Gln Ala Gln Glu Asn Pro Gly Tyr Pro Tyr Ser Asp Ser Ser
                 560                 565                 570

 Ser Ile Leu Gly Glu Asn Pro His Ile Gly Ile Asp Met Ile Asp
                 575                 580                 585

 Asn Asp Gln Gly Ser Ser Ser Pro Ser Asn Asp Glu Ala Ala Met
                 590                 595                 600

 Ala Val Ile Met Ser Leu Leu Glu Ala Asp Ala Gly Leu Gly Gly
                 605                 610                 615

 Pro Val Asp Phe Ser Asp Leu Pro Trp Pro Leu
                 620                 625

<210> 2321
<211> 4049
<212> DNA
<213> Homo sapien

<400> 2321
 cctcttgcgg ccacaggcgc ggcgtcctcg gcggcgggcg gcagctagcg 50

 ggagccggga cgccggtgca gccgcagcgc gcggaggaac ccgggtgtgc 100

 cgggagctgg gcggccacgt ccggacggga ccgagacccc tcgtagcgca 150

 ttgcggcgac ctcgccttcc ccggccgcga gcgcgccgct gcttgaaaag 200

 ccgcggaacc caaggacttt tctccggtcc gagctcgggg cgccccgcag 250

 gcgcacggta cccgtgctgc agtcgggcac gccgcggcgc cgggggcctc 300

 cgcagggcga tggagccggt ctgcaaggaa agtgaggcgc cgccgctgcg 350

 ttctggagga ggggggcaca aggtctggag accccgggtg gcggacggga 400

 gccctccccc cgccccgcct ccggggcacc agctccggct ccattgttcc 450

 cgcccgggct ggaggcgccg agcaccgagc gccgccggga gtcgagcgcc 500

 ggccgcggag ctcttgcgac cccgccagga cccgaacaga gcccgggggc 550

 ggcgggccgg agccggggac gcgggcacac gcccgctcgc acaagccacg 600

 gcggactctc ccgaggcgga acctccacgc cgagcgaggg tcagtttgaa 650

 aaggaggatc gagctcactg tggagtatcc atggagatgt ggagccttgt 700

 caccaacctc taactgcaga actgggatgt ggagctggaa gtgcctcctc 750

 ttctgggctg tgctggtcac agccacactc tgcaccgcta ggccgtcccc 800

 gaccttgcct gaacaagccc agccctgggg agcccctgtg gaagtggagt 850

 ccttcctggt ccaccccggt gacctgctgc agcttcgctg tcggctgcgg 900

 gacgatgtgc agagcatcaa ctggctgcgg gacggggtgc agctggcgga 950

 aagcaaccgc acccgcatca caggggagga ggtggaggtg caggactccg 1000

 tgcccgcaga ctccggcctc tatgcttgcg taaccagcag cccctcgggc 1050

 agtgacacca cctacttctc cgtcaatgtt tcagatgctc tcccctcctc 1100

 ggaggatgat gatgatgatg atgactcctc ttcagaggag aaagaaacag 1150

 ataacaccaa accaaaccgt atgcccgtag ctccatattg gacatcccca 1200

 gaaaagatgg aaaagaaatt gcatgcagtg ccggctgcca agacagtgaa 1250

 gttcaaatgc ccttccagtg ggaccccaaa ccccacactg cgctggttga 1300

 aaaatggcaa agaattcaaa cctgaccaca gaattggagg ctacaaggtc 1350

 cgttatgcca cctggagcat cataatggac tctgtggtgc cctctgacaa 1400

 gggcaactac acctgcattg tggagaatga gtacggcagc atcaaccaca 1450

 cataccagct ggatgtcgtg gagcggtccc ctcaccggcc catcctgcaa 1500

 gcagggttgc ccgccaacaa aacagtggcc ctgggtagca acgtggagtt 1550

 catgtgtaag gtgtacagtg acccgcagcc gcacatccag tggctaaagc 1600

 acatcgaggt gaatgggagc aagattggcc cagacaacct gccttatgtc 1650

 cagatcttga agactgctgg agttaatacc accgacaaag agatggaggt 1700

 gcttcactta agaaatgtct cctttgagga cgcaggggag tatacgtgct 1750

 tggcgggtaa ctctatcgga ctctcccatc actctgcatg gttgaccgtt 1800

 ctggaagccc tggaagagag gccggcagtg atgacctcgc ccctgtacct 1850

 ggagatcatc atctattgca caggggcctt cctcatctcc tgcatggtgg 1900

 ggtcggtcat cgtctacaag atgaagagtg gtaccaagaa gagtgacttc 1950

 cacagccaga tggctgtgca caagctggcc aagagcatcc ctctgcgcag 2000

 acaggtaaca gtgtctgctg actccagtgc atccatgaac tctggggttc 2050

 ttctggttcg gccatcacgg ctctcctcca gtgggactcc catgctagca 2100

 ggggtctctg agtatgagct tcccgaagac cctcgctggg agctgcctcg 2150

 ggacagactg gtcttaggca aacccctggg agagggctgc tttgggcagg 2200

 tggtgttggc agaggctatc gggctggaca aggacaaacc caaccgtgtg 2250

 accaaagtgg ctgtgaagat gttgaagtcg gacgcaacag agaaagactt 2300

 gtcagacctg atctcagaaa tggagatgat gaagatgatc gggaagcata 2350

 agaatatcat caacctgctg ggggcctgca cgcaggatgg tcccttgtat 2400

 gtcatcgtgg agtatgcctc caagggcaac ctgcgggagt acctgcaggc 2450

 ccggaggccc ccagggctgg aatactgcta caaccccagc cacaacccag 2500

 aggagcagct ctcctccaag gacctggtgt cctgcgccta ccaggtggcc 2550

 cgaggcatgg agtatctggc ctccaagaag tgcatacacc gagacctggc 2600

 agccaggaat gtcctggtga cagaggacaa tgtgatgaag atagcagact 2650

 ttggcctcgc acgggacatt caccacatcg actactataa aaagacaacc 2700

 aacggccgac tgcctgtgaa gtggatggca cccgaggcat tatttgaccg 2750

 gatctacacc caccagagtg atgtgtggtc tttcggggtg ctcctgtggg 2800

 agatcttcac tctgggcggc tccccatacc ccggtgtgcc tgtggaggaa 2850

 cttttcaagc tgctgaagga gggtcaccgc atggacaagc ccagtaactg 2900

 caccaacgag ctgtacatga tgatgcggga ctgctggcat gcagtgccct 2950

 cacagagacc caccttcaag cagctggtgg aagacctgga ccgcatcgtg 3000

 gccttgacct ccaaccagga gtacctggac ctgtccatgc ccctggacca 3050

 gtactccccc agctttcccg acacccggag ctctacgtgc tcctcagggg 3100

 aggattccgt cttctctcat gagccgctgc ccgaggagcc ctgcctgccc 3150

 cgacacccag cccagcttgc caatggcgga ctcaaacgcc gctgactgcc 3200

 acccacacgc cctccccaga ctccaccgtc agctgtaacc ctcacccaca 3250

 gcccctgctg ggcccaccac ctgtccgtcc ctgtcccctt tcctgctggc 3300

 aggagccggc tgcctaccag gggccttcct gtgtggcctg ccttcacccc 3350

 actcagctca cctctccctc cacctcctct ccacctgctg gtgagaggtg 3400

 caaagaggca gatctttgct gccagccact tcatcccctc ccagatgttg 3450

 gaccaacacc cctccctgcc accaggcact gcctggaggg cagggagtgg 3500

 gagccaatga acaggcatgc aagtgagagc ttcctgagct ttctcctgtc 3550

 ggtttggtct gttttgcctt cacccataag cccctcgcac tctggtggca 3600

 ggtgccttgt cctcagggct acagcagtag ggaggtcagt gcttcgtgcc 3650

 tcgattgaag gtgacctctg ccccagatag gtggtgccag tggcttatta 3700

 attccgatac tagtttgctt tgctgaccaa atgcctggta ccagaggatg 3750

 gtgaggcgaa ggccaggttg ggggcagtgt tgtggccctg gggcccagcc 3800

 ccaaactggg ggctctgtat atagctatga agaaaacaca aagtgtataa 3850

 atctgagtat atatttacat gtctttttaa aagggtcgtt accagagatt 3900

 tacccatcgg gtaagatgct cctggtggct gggaggcatc agttgctata 3950

 tattaaaaac aaaaaagaaa aaaaaggaaa atgtttttaa aaaggtcata 4000

 tattttttgc tacttttgct gttttatttt tttaaattat gttctaaac 4049

<210> 2322
<211> 822
<212> PRT
<213> Homo sapien

<400> 2322
 Met Trp Ser Trp Lys Cys Leu Leu Phe Trp Ala Val Leu Val Thr
   1               5                  10                  15

 Ala Thr Leu Cys Thr Ala Arg Pro Ser Pro Thr Leu Pro Glu Gln
                  20                  25                  30

 Ala Gln Pro Trp Gly Ala Pro Val Glu Val Glu Ser Phe Leu Val
                  35                  40                  45

 His Pro Gly Asp Leu Leu Gln Leu Arg Cys Arg Leu Arg Asp Asp
                  50                  55                  60

 Val Gln Ser Ile Asn Trp Leu Arg Asp Gly Val Gln Leu Ala Glu
                  65                  70                  75

 Ser Asn Arg Thr Arg Ile Thr Gly Glu Glu Val Glu Val Gln Asp
                  80                  85                  90

 Ser Val Pro Ala Asp Ser Gly Leu Tyr Ala Cys Val Thr Ser Ser
                  95                 100                 105

 Pro Ser Gly Ser Asp Thr Thr Tyr Phe Ser Val Asn Val Ser Asp
                 110                 115                 120

 Ala Leu Pro Ser Ser Glu Asp Asp Asp Asp Asp Asp Asp Ser Ser
                 125                 130                 135

 Ser Glu Glu Lys Glu Thr Asp Asn Thr Lys Pro Asn Arg Met Pro
                 140                 145                 150

 Val Ala Pro Tyr Trp Thr Ser Pro Glu Lys Met Glu Lys Lys Leu
                 155                 160                 165

 His Ala Val Pro Ala Ala Lys Thr Val Lys Phe Lys Cys Pro Ser
                 170                 175                 180

 Ser Gly Thr Pro Asn Pro Thr Leu Arg Trp Leu Lys Asn Gly Lys
                 185                 190                 195

 Glu Phe Lys Pro Asp His Arg Ile Gly Gly Tyr Lys Val Arg Tyr
                 200                 205                 210

 Ala Thr Trp Ser Ile Ile Met Asp Ser Val Val Pro Ser Asp Lys
                 215                 220                 225

 Gly Asn Tyr Thr Cys Ile Val Glu Asn Glu Tyr Gly Ser Ile Asn
                 230                 235                 240

 His Thr Tyr Gln Leu Asp Val Val Glu Arg Ser Pro His Arg Pro
                 245                 250                 255

 Ile Leu Gln Ala Gly Leu Pro Ala Asn Lys Thr Val Ala Leu Gly
                 260                 265                 270

 Ser Asn Val Glu Phe Met Cys Lys Val Tyr Ser Asp Pro Gln Pro
                 275                 280                 285

 His Ile Gln Trp Leu Lys His Ile Glu Val Asn Gly Ser Lys Ile
                 290                 295                 300

 Gly Pro Asp Asn Leu Pro Tyr Val Gln Ile Leu Lys Thr Ala Gly
                 305                 310                 315

 Val Asn Thr Thr Asp Lys Glu Met Glu Val Leu His Leu Arg Asn
                 320                 325                 330

 Val Ser Phe Glu Asp Ala Gly Glu Tyr Thr Cys Leu Ala Gly Asn
                 335                 340                 345

 Ser Ile Gly Leu Ser His His Ser Ala Trp Leu Thr Val Leu Glu
                 350                 355                 360

 Ala Leu Glu Glu Arg Pro Ala Val Met Thr Ser Pro Leu Tyr Leu
                 365                 370                 375

 Glu Ile Ile Ile Tyr Cys Thr Gly Ala Phe Leu Ile Ser Cys Met
                 380                 385                 390

 Val Gly Ser Val Ile Val Tyr Lys Met Lys Ser Gly Thr Lys Lys
                 395                 400                 405

 Ser Asp Phe His Ser Gln Met Ala Val His Lys Leu Ala Lys Ser
                 410                 415                 420

 Ile Pro Leu Arg Arg Gln Val Thr Val Ser Ala Asp Ser Ser Ala
                 425                 430                 435

 Ser Met Asn Ser Gly Val Leu Leu Val Arg Pro Ser Arg Leu Ser
                 440                 445                 450

 Ser Ser Gly Thr Pro Met Leu Ala Gly Val Ser Glu Tyr Glu Leu
                 455                 460                 465

 Pro Glu Asp Pro Arg Trp Glu Leu Pro Arg Asp Arg Leu Val Leu
                 470                 475                 480

 Gly Lys Pro Leu Gly Glu Gly Cys Phe Gly Gln Val Val Leu Ala
                 485                 490                 495

 Glu Ala Ile Gly Leu Asp Lys Asp Lys Pro Asn Arg Val Thr Lys
                 500                 505                 510

 Val Ala Val Lys Met Leu Lys Ser Asp Ala Thr Glu Lys Asp Leu
                 515                 520                 525

 Ser Asp Leu Ile Ser Glu Met Glu Met Met Lys Met Ile Gly Lys
                 530                 535                 540

 His Lys Asn Ile Ile Asn Leu Leu Gly Ala Cys Thr Gln Asp Gly
                 545                 550                 555

 Pro Leu Tyr Val Ile Val Glu Tyr Ala Ser Lys Gly Asn Leu Arg
                 560                 565                 570

 Glu Tyr Leu Gln Ala Arg Arg Pro Pro Gly Leu Glu Tyr Cys Tyr
                 575                 580                 585

 Asn Pro Ser His Asn Pro Glu Glu Gln Leu Ser Ser Lys Asp Leu
                 590                 595                 600

 Val Ser Cys Ala Tyr Gln Val Ala Arg Gly Met Glu Tyr Leu Ala
                 605                 610                 615

 Ser Lys Lys Cys Ile His Arg Asp Leu Ala Ala Arg Asn Val Leu
                 620                 625                 630

 Val Thr Glu Asp Asn Val Met Lys Ile Ala Asp Phe Gly Leu Ala
                 635                 640                 645

 Arg Asp Ile His His Ile Asp Tyr Tyr Lys Lys Thr Thr Asn Gly
                 650                 655                 660

 Arg Leu Pro Val Lys Trp Met Ala Pro Glu Ala Leu Phe Asp Arg
                 665                 670                 675

 Ile Tyr Thr His Gln Ser Asp Val Trp Ser Phe Gly Val Leu Leu
                 680                 685                 690

 Trp Glu Ile Phe Thr Leu Gly Gly Ser Pro Tyr Pro Gly Val Pro
                 695                 700                 705

 Val Glu Glu Leu Phe Lys Leu Leu Lys Glu Gly His Arg Met Asp
                 710                 715                 720

 Lys Pro Ser Asn Cys Thr Asn Glu Leu Tyr Met Met Met Arg Asp
                 725                 730                 735

 Cys Trp His Ala Val Pro Ser Gln Arg Pro Thr Phe Lys Gln Leu
                 740                 745                 750

 Val Glu Asp Leu Asp Arg Ile Val Ala Leu Thr Ser Asn Gln Glu
                 755                 760                 765

 Tyr Leu Asp Leu Ser Met Pro Leu Asp Gln Tyr Ser Pro Ser Phe
                 770                 775                 780

 Pro Asp Thr Arg Ser Ser Thr Cys Ser Ser Gly Glu Asp Ser Val
                 785                 790                 795

 Phe Ser His Glu Pro Leu Pro Glu Glu Pro Cys Leu Pro Arg His
                 800                 805                 810

 Pro Ala Gln Leu Ala Asn Gly Gly Leu Lys Arg Arg
                 815                 820

<210> 2323
<211> 2258
<212> DNA
<213> Homo sapien

<400> 2323
 ggcgttggct gctagagcga tgccgggccg gagttgcgtc gccttagtcc 50

 tcctggctgc cgcgtcagct gtgccgtcgc agcacgcgcc gccgtggaca 100

 gaggactgca gaaaatcaac ctatcctcct tcaggaccaa cgtacagagg 150

 tgcagttcca tggtacacca taaatcttga cttaccaccc tacaaaagat 200

 ggcatgaatt gatgcttgac aaggcaccaa tgctaaaggt tatagtgaat 250

 tctctgaaga atatgataaa tacattcgtg ccaagtggaa aagttatgca 300

 ggtggtggat gaaaaattgc ctggcctact tggcaacttt cctggccctt 350

 ttgaagagga aatgaagggt attgccgctg ttactgatat acctttagga 400

 gagattattt cattcaatat tttttatgaa ttatttacca tttgtacttc 450

 aatagtagca gaagacaaaa aaggtcatct aatacatggg agaaacatgg 500

 attttggagt atttcttggg tggaacataa ataatgatac ctgggtcata 550

 actgagcaac taaaaccttt aacagtgaat ttggatttcc aaagaaacaa 600

 caaaactgtc ttcaaggctt caagctttgc tggctatgtg ggcatgttaa 650

 caggattcaa accaggactg ttcagtctta cactgaatga acgtttcagt 700

 ataaatggtg gttatctggg tattctagaa tggattctgg gaaagaaaga 750

 tgccatgtgg atagggttcc tcactagaac agttctggaa aatagcacaa 800

 gttatgaaga agccaagaat ttattgacca agaccaagat attggcccca 850

 gcctacttta tcctgggagg caaccagtct ggggaaggtt gtgtgattac 900

 acgagacaga aaggaatcat tggatgtata tgaactcgat gctaagcagg 950

 gtagatggta tgtggtacaa acaaattatg accgttggaa acatcccttc 1000

 ttccttgatg atcgcagaac gcctgcaaag atgtgtctga accgcaccag 1050

 ccaagagaat atctcatttg aaaccatgta tgatgtcctg tcaacaaaac 1100

 ctgtcctcaa caagctgacc gtatacacaa ccttgataga tgttaccaaa 1150

 ggtcaattcg aaacttacct gcgggactgc cctgaccctt gtataggttg 1200

 gtgagcacac gtctggccta cagaatgcgg cctctgagac atgaagacac 1250

 catctccatg tgaccgaaca ctgcagctgt ctgaccttcc aaagactaag 1300

 actcgcggca ggttctcttt gagtcaatag cttgtcttcg tccatctgtt 1350

 gacaaatgac agactttttt tttttccccc tatcagttga tttttcttat 1400

 ttatagataa cttctttagg ggaagtaaaa cagtcatcta gaattcactg 1450

 agttttgttt cactttgaca tttggggatc tggtgggcag tcgaaccatg 1500

 gtgaactcca cctccgtgaa taaatggaga ttcagcgtgg gtgttgaatc 1550

 cagcacgtct gtgtgagtaa cgggacagta aacactccac attcttcagt 1600

 ttttcacttc tacctacata tttgtatgtt tttctgtata acagcctttt 1650

 ccttctggtt ctaactgctg ttaaaattaa tatatcatta tctttgctgt 1700

 tattgacagc gatataattt tattacatat gattagaggg atgagacaga 1750

 cattcacctg tatatttctt ttaatgggca caaaattggt gcctttgcct 1800

 ctaaatagca ctttttcggg gtcaagaagt aatcagatgc aaagcaatcg 1850

 tttatacaat aattgaagcg cacctttcaa taccactcca gtacctaagg 1900

 aagtgctact aaactgcatc cacgtctgta tagtaataac agtcaagctg 1950

 gaatcgagga ccaattaatt ccaatggcac agagtagcat tcatgtaata 2000

 aacaggtttt tagtttgttc ttcagattga tagggagttt taaagaaatt 2050

 ttagtagtta ctaaaattat gttactgtat ttttcagaaa tccaactgct 2100

 tatgaaaagt actaatagaa cttgttaacc tttctaacct tcacgattaa 2150

 ctgtgaaatg tacgtcattt gtgcaagacc gtttgtccac ttcattttgt 2200

 ataatcacag ttgtgttcct gacactcaat aaacagtcat tggaaagaga 2250

 aaaaaaaa 2258

<210> 2324
<211> 394
<212> PRT
<213> Homo sapien

<400> 2324
 Met Pro Gly Arg Ser Cys Val Ala Leu Val Leu Leu Ala Ala Ala
   1               5                  10                  15

 Ser Ala Val Pro Ser Gln His Ala Pro Pro Trp Thr Glu Asp Cys
                  20                  25                  30

 Arg Lys Ser Thr Tyr Pro Pro Ser Gly Pro Thr Tyr Arg Gly Ala
                  35                  40                  45

 Val Pro Trp Tyr Thr Ile Asn Leu Asp Leu Pro Pro Tyr Lys Arg
                  50                  55                  60

 Trp His Glu Leu Met Leu Asp Lys Ala Pro Met Leu Lys Val Ile
                  65                  70                  75

 Val Asn Ser Leu Lys Asn Met Ile Asn Thr Phe Val Pro Ser Gly
                  80                  85                  90

 Lys Val Met Gln Val Val Asp Glu Lys Leu Pro Gly Leu Leu Gly
                  95                 100                 105

 Asn Phe Pro Gly Pro Phe Glu Glu Glu Met Lys Gly Ile Ala Ala
                 110                 115                 120

 Val Thr Asp Ile Pro Leu Gly Glu Ile Ile Ser Phe Asn Ile Phe
                 125                 130                 135

 Tyr Glu Leu Phe Thr Ile Cys Thr Ser Ile Val Ala Glu Asp Lys
                 140                 145                 150

 Lys Gly His Leu Ile His Gly Arg Asn Met Asp Phe Gly Val Phe
                 155                 160                 165

 Leu Gly Trp Asn Ile Asn Asn Asp Thr Trp Val Ile Thr Glu Gln
                 170                 175                 180

 Leu Lys Pro Leu Thr Val Asn Leu Asp Phe Gln Arg Asn Asn Lys
                 185                 190                 195

 Thr Val Phe Lys Ala Ser Ser Phe Ala Gly Tyr Val Gly Met Leu
                 200                 205                 210

 Thr Gly Phe Lys Pro Gly Leu Phe Ser Leu Thr Leu Asn Glu Arg
                 215                 220                 225

 Phe Ser Ile Asn Gly Gly Tyr Leu Gly Ile Leu Glu Trp Ile Leu
                 230                 235                 240

 Gly Lys Lys Asp Ala Met Trp Ile Gly Phe Leu Thr Arg Thr Val
                 245                 250                 255

 Leu Glu Asn Ser Thr Ser Tyr Glu Glu Ala Lys Asn Leu Leu Thr
                 260                 265                 270

 Lys Thr Lys Ile Leu Ala Pro Ala Tyr Phe Ile Leu Gly Gly Asn
                 275                 280                 285

 Gln Ser Gly Glu Gly Cys Val Ile Thr Arg Asp Arg Lys Glu Ser
                 290                 295                 300

 Leu Asp Val Tyr Glu Leu Asp Ala Lys Gln Gly Arg Trp Tyr Val
                 305                 310                 315

 Val Gln Thr Asn Tyr Asp Arg Trp Lys His Pro Phe Phe Leu Asp
                 320                 325                 330

 Asp Arg Arg Thr Pro Ala Lys Met Cys Leu Asn Arg Thr Ser Gln
                 335                 340                 345

 Glu Asn Ile Ser Phe Glu Thr Met Tyr Asp Val Leu Ser Thr Lys
                 350                 355                 360

 Pro Val Leu Asn Lys Leu Thr Val Tyr Thr Thr Leu Ile Asp Val
                 365                 370                 375

 Thr Lys Gly Gln Phe Glu Thr Tyr Leu Arg Asp Cys Pro Asp Pro
                 380                 385                 390

 Cys Ile Gly Trp


<210> 2325
<211> 2848
<212> DNA
<213> Homo sapien

<400> 2325
 cgcggcactc gcgcgcgatc ccggccggcg gcgcgccggc gggccaggcg 50

 gcgccacagc ccatggagct cgagaacatc gtagcgaaca cggtgctact 100

 caaggcccgg gaaggtggcg gtggaaatcg caaaggcaaa agcaagaaat 150

 ggcggcagat gctccagttc cctcacatca gccagtgcga agagctgcgg 200

 ctcagcctcg agcgtgacta tcacagcctg tgcgagcggc acgccattgg 250

 gcgcctgctg ttccgagagt tctgtgccac gaggccggag ctgagccgct 300

 gcgtcgcctt cctggatggg gtggccgagt atgaagtgac cccggatgac 350

 aagcggaagg catgtgggcg gcacgtaacg cagaattttc tgagccacac 400

 gggtcctgac ctcatccctg aggtcccccg gcagctggtg acgaactgca 450

 cccagcggct ggagcagggt ccctgcaaag accttttcca ggaactcacc 500

 cggctgaccc acgagtacct gagcgtggcc ccttttgccg actacctcga 550

 cagcatctac ttcaaccgtt tcctgcagtg gaagtggctg gaaaggcagc 600

 cagtgaccaa aaacaccttc aggcaatacc gagtcctggg caaaggtggc 650

 tttggggagg tgtgcgcctg ccaggtgcgg gccacaggta agatgtatgc 700

 ctgcaagaag ctagagaaaa agcggatcaa gaagcggaaa ggggaggcca 750

 tggcgctgaa cgagaagcag atcctggaga aagtgaacag taggtttgta 800

 gtgagcttgg cctacgccta tgagaccaag gacgcgctgt gcctggtgct 850

 gacactgatg aacgggggcg acctcaagtt ccacatctac cacatgggcc 900

 aggctggctt ccccgaagcg cgggccgtct tctacgccgc cgagatctgc 950

 tgtggcctgg aggacctgca ccgggagcgc atcgtgtaca gggacctgaa 1000

 gcccgagaac atcttgctgg atgaccacgg ccacatccgc atctctgacc 1050

 tgggactagc tgtgcatgtg cccgagggcc agaccatcaa agggcgtgtg 1100

 ggcaccgtgg gttacatggc tccggaggtg gtgaagaatg aacggtacac 1150

 gttcagccct gactggtggg cgctcggctg cctcctgtac gagatgatcg 1200

 caggccagtc gcccttccag cagaggaaga agaagatcaa gcgggaggag 1250

 gtggagcggc tggtgaagga ggtccccgag gagtattccg agcgcttttc 1300

 cccgcaggcc cgctcacttt gctcacagct cctctgcaag gaccctgccg 1350

 aacgcctggg gtgtcgtggg ggcagtgccc gcgaggtgaa ggagcacccc 1400

 ctctttaaga agctgaactt caagcggctg ggagctggca tgctggagcc 1450

 gccgttcaag cctgaccccc aggccattta ctgcaaggat gttctggaca 1500

 ttgaacagtt ctctacggtc aagggcgtgg agctggagcc taccgaccag 1550

 gacttctacc agaagtttgc cacaggcagt gtgcccatcc cctggcagaa 1600

 cgagatggtg gagaccgagt gcttccaaga gctgaatgtc tttgggctgg 1650

 atggctcagt tcccccagac ctggactgga agggccagcc acctgcacct 1700

 cctaaaaagg gactgctgca gagactcttc agtcgccaag attgctgtgg 1750

 aaactgcagc gacagcgagg aagagctccc cacccgcctc tagcccccag 1800

 cccgaggccc ccaccagcag ttggcggtag cagctactcc gagcgccgtt 1850

 tacagttttg cacagtgatc ttccccattg tccactcaag tcgtggcctg 1900

 gggaacacag acggagctgt ccccagtgtc ctccgtccct cagcccctgg 1950

 cctggctgag tttggcaggg cctgggccat ccctgggaca aaggtgcgtc 2000

 ccttcagctc ttctccgtgg agctcggggc tttctgtatt tatgtatttg 2050

 tacgaatgta tatagcgacc agagcattct taattcccgc cgcagacctg 2100

 gcgcccccgc cttggctcct gggggcagcc agccctggct ggagagcggg 2150

 acgtggcaga ggagccactg ccaaactcaa ggctcctctg gcccagcttg 2200

 gatggctgag ggtggtcaca cctgagcctt cagcactgtg ctgccacccc 2250

 ggcctctgag taagactcgt gcctccccct gctgccctgg gctcaggctg 2300

 ctacctctgg ggcccaaagc tgtcccttct cagtgcttgt cagcgctggg 2350

 tctggggcct ctgtatgccc taggcctgtg ccaaagtggc cagagattgg 2400

 gctgcctgtg atacccatca gcccactgcc ccggccggcc cagataggtc 2450

 tgcctctgcc ttccagctcc cacagcctgg tccctgatac tgggctctgt 2500

 cctgcagaca cctctttcag aaacgcccaa gcccagccct aggagggggt 2550

 ggggcatccc tggtcaaccc tcaaacattc cggactcccc tcataacaat 2600

 agacacatgt gcccagcaat aatccgcccc ttcctgtgtg cgcctgtggg 2650

 gtgcgtgctc tctgtgtgta cctgtgtggg tgaaggggat agggcgaggc 2700

 tgtgcctgtg ccccaggtcc cagccctggc ccttcccaga ctgtgatggc 2750

 catcctggtc ccagtgttag ggtagcatgg gattacaggg ccctgttttt 2800

 tccatattta aagccaattt ttattactcg ttttgtccaa cgtaaaag 2848

<210> 2326
<211> 576
<212> PRT
<213> Homo sapien

<400> 2326
 Met Glu Leu Glu Asn Ile Val Ala Asn Thr Val Leu Leu Lys Ala
   1               5                  10                  15

 Arg Glu Gly Gly Gly Gly Asn Arg Lys Gly Lys Ser Lys Lys Trp
                  20                  25                  30

 Arg Gln Met Leu Gln Phe Pro His Ile Ser Gln Cys Glu Glu Leu
                  35                  40                  45

 Arg Leu Ser Leu Glu Arg Asp Tyr His Ser Leu Cys Glu Arg His
                  50                  55                  60

 Ala Ile Gly Arg Leu Leu Phe Arg Glu Phe Cys Ala Thr Arg Pro
                  65                  70                  75

 Glu Leu Ser Arg Cys Val Ala Phe Leu Asp Gly Val Ala Glu Tyr
                  80                  85                  90

 Glu Val Thr Pro Asp Asp Lys Arg Lys Ala Cys Gly Arg His Val
                  95                 100                 105

 Thr Gln Asn Phe Leu Ser His Thr Gly Pro Asp Leu Ile Pro Glu
                 110                 115                 120

 Val Pro Arg Gln Leu Val Thr Asn Cys Thr Gln Arg Leu Glu Gln
                 125                 130                 135

 Gly Pro Cys Lys Asp Leu Phe Gln Glu Leu Thr Arg Leu Thr His
                 140                 145                 150

 Glu Tyr Leu Ser Val Ala Pro Phe Ala Asp Tyr Leu Asp Ser Ile
                 155                 160                 165

 Tyr Phe Asn Arg Phe Leu Gln Trp Lys Trp Leu Glu Arg Gln Pro
                 170                 175                 180

 Val Thr Lys Asn Thr Phe Arg Gln Tyr Arg Val Leu Gly Lys Gly
                 185                 190                 195

 Gly Phe Gly Glu Val Cys Ala Cys Gln Val Arg Ala Thr Gly Lys
                 200                 205                 210

 Met Tyr Ala Cys Lys Lys Leu Glu Lys Lys Arg Ile Lys Lys Arg
                 215                 220                 225

 Lys Gly Glu Ala Met Ala Leu Asn Glu Lys Gln Ile Leu Glu Lys
                 230                 235                 240

 Val Asn Ser Arg Phe Val Val Ser Leu Ala Tyr Ala Tyr Glu Thr
                 245                 250                 255

 Lys Asp Ala Leu Cys Leu Val Leu Thr Leu Met Asn Gly Gly Asp
                 260                 265                 270

 Leu Lys Phe His Ile Tyr His Met Gly Gln Ala Gly Phe Pro Glu
                 275                 280                 285

 Ala Arg Ala Val Phe Tyr Ala Ala Glu Ile Cys Cys Gly Leu Glu
                 290                 295                 300

 Asp Leu His Arg Glu Arg Ile Val Tyr Arg Asp Leu Lys Pro Glu
                 305                 310                 315

 Asn Ile Leu Leu Asp Asp His Gly His Ile Arg Ile Ser Asp Leu
                 320                 325                 330

 Gly Leu Ala Val His Val Pro Glu Gly Gln Thr Ile Lys Gly Arg
                 335                 340                 345

 Val Gly Thr Val Gly Tyr Met Ala Pro Glu Val Val Lys Asn Glu
                 350                 355                 360

 Arg Tyr Thr Phe Ser Pro Asp Trp Trp Ala Leu Gly Cys Leu Leu
                 365                 370                 375

 Tyr Glu Met Ile Ala Gly Gln Ser Pro Phe Gln Gln Arg Lys Lys
                 380                 385                 390

 Lys Ile Lys Arg Glu Glu Val Glu Arg Leu Val Lys Glu Val Pro
                 395                 400                 405

 Glu Glu Tyr Ser Glu Arg Phe Ser Pro Gln Ala Arg Ser Leu Cys
                 410                 415                 420

 Ser Gln Leu Leu Cys Lys Asp Pro Ala Glu Arg Leu Gly Cys Arg
                 425                 430                 435

 Gly Gly Ser Ala Arg Glu Val Lys Glu His Pro Leu Phe Lys Lys
                 440                 445                 450

 Leu Asn Phe Lys Arg Leu Gly Ala Gly Met Leu Glu Pro Pro Phe
                 455                 460                 465

 Lys Pro Asp Pro Gln Ala Ile Tyr Cys Lys Asp Val Leu Asp Ile
                 470                 475                 480

 Glu Gln Phe Ser Thr Val Lys Gly Val Glu Leu Glu Pro Thr Asp
                 485                 490                 495

 Gln Asp Phe Tyr Gln Lys Phe Ala Thr Gly Ser Val Pro Ile Pro
                 500                 505                 510

 Trp Gln Asn Glu Met Val Glu Thr Glu Cys Phe Gln Glu Leu Asn
                 515                 520                 525

 Val Phe Gly Leu Asp Gly Ser Val Pro Pro Asp Leu Asp Trp Lys
                 530                 535                 540

 Gly Gln Pro Pro Ala Pro Pro Lys Lys Gly Leu Leu Gln Arg Leu
                 545                 550                 555

 Phe Ser Arg Gln Asp Cys Cys Gly Asn Cys Ser Asp Ser Glu Glu
                 560                 565                 570

 Glu Leu Pro Thr Arg Leu
                 575

<210> 2327
<211> 1237
<212> DNA
<213> Homo sapien

<400> 2327
 attcttgtct gttctgcctc actcccgagc tctactgact cccaaaagag 50

 cgcccaagaa gaaaatggcc ataagtggag tccctgtgct aggatttttc 100

 atcatagctg tgctgatgag cgctcaggaa tcatgggcta tcaaagaaga 150

 acatgtgatc atccaggccg agttctatct gaatcctgac caatcaggcg 200

 agtttatgtt tgactttgat ggtgatgaga ttttccatgt ggatatggca 250

 aagaaggaga cggtctggcg gcttgaagaa tttggacgat ttgccagctt 300

 tgaggctcaa ggtgcattgg ccaacatagc tgtggacaaa gccaacctgg 350

 aaatcatgac aaagcgctcc aactatactc cgatcaccaa tgtacctcca 400

 gaggtaactg tgctcacgaa cagccctgtg gaactgagag agcccaacgt 450

 cctcatctgt ttcatcgaca agttcacccc accagtggtc aatgtcacgt 500

 ggcttcgaaa tggaaaacct gtcaccacag gagtgtcaga gacagtcttc 550

 ctgcccaggg aagaccacct tttccgcaag ttccactatc tccccttcct 600

 gccctcaact gaggacgttt acgactgcag ggtggagcac tggggcttgg 650

 atgagcctct tctcaagcac tgggagtttg atgctccaag ccctctccca 700

 gagactacag agaacgtggt gtgtgccctg ggcctgactg tgggtctggt 750

 gggcatcatt attgggacca tcttcatcat caagggagtg cgcaaaagca 800

 atgcagcaga acgcaggggg cctctgtaag gcacatggag gtgatgatgt 850

 ttcttagaga gaagatcact gaagaaactt ctgctttaat gactttacaa 900

 agctggcaat attacaatcc ttgacctcag tgaaagcagt catcttcagc 950

 gttttccagc cctatagcca ccccaagtgt ggttatgcct cctcgattgc 1000

 tccgtactct aacatctagc tggctttccc tgtctattgc cttttcctgt 1050

 atctattttc ctctatttcc tatcatttta ttatcaccat gcaatgcctc 1100

 tggaataaaa catacaggag tctgtctctg ctatggaatg ccccatgggg 1150

 ctctcttgtg tacttattgt ttaaggtttc ctcaaactgt gatttttctg 1200

 aacacaataa actattttga tgatcttggg tggaaaa 1237

<210> 2328
<211> 254
<212> PRT
<213> Homo sapien

<400> 2328
 Met Ala Ile Ser Gly Val Pro Val Leu Gly Phe Phe Ile Ile Ala
   1               5                  10                  15

 Val Leu Met Ser Ala Gln Glu Ser Trp Ala Ile Lys Glu Glu His
                  20                  25                  30

 Val Ile Ile Gln Ala Glu Phe Tyr Leu Asn Pro Asp Gln Ser Gly
                  35                  40                  45

 Glu Phe Met Phe Asp Phe Asp Gly Asp Glu Ile Phe His Val Asp
                  50                  55                  60

 Met Ala Lys Lys Glu Thr Val Trp Arg Leu Glu Glu Phe Gly Arg
                  65                  70                  75

 Phe Ala Ser Phe Glu Ala Gln Gly Ala Leu Ala Asn Ile Ala Val
                  80                  85                  90

 Asp Lys Ala Asn Leu Glu Ile Met Thr Lys Arg Ser Asn Tyr Thr
                  95                 100                 105

 Pro Ile Thr Asn Val Pro Pro Glu Val Thr Val Leu Thr Asn Ser
                 110                 115                 120

 Pro Val Glu Leu Arg Glu Pro Asn Val Leu Ile Cys Phe Ile Asp
                 125                 130                 135

 Lys Phe Thr Pro Pro Val Val Asn Val Thr Trp Leu Arg Asn Gly
                 140                 145                 150

 Lys Pro Val Thr Thr Gly Val Ser Glu Thr Val Phe Leu Pro Arg
                 155                 160                 165

 Glu Asp His Leu Phe Arg Lys Phe His Tyr Leu Pro Phe Leu Pro
                 170                 175                 180

 Ser Thr Glu Asp Val Tyr Asp Cys Arg Val Glu His Trp Gly Leu
                 185                 190                 195

 Asp Glu Pro Leu Leu Lys His Trp Glu Phe Asp Ala Pro Ser Pro
                 200                 205                 210

 Leu Pro Glu Thr Thr Glu Asn Val Val Cys Ala Leu Gly Leu Thr
                 215                 220                 225

 Val Gly Leu Val Gly Ile Ile Ile Gly Thr Ile Phe Ile Ile Lys
                 230                 235                 240

 Gly Val Arg Lys Ser Asn Ala Ala Glu Arg Arg Gly Pro Leu
                 245                 250

<210> 2329
<211> 2427
<212> DNA
<213> Homo sapien

<400> 2329
 gacgtttcgc gccaatttcg gttggccggc cacagtccac cgcgcggaga 50

 ttctcagctt ccccaggagc aagacctctg agcccgccaa gcgcggccgc 100

 acggccctcg gcagcgatgg cactgaagga ctacgcgcta gagaaggaaa 150

 aggttaagaa gttcttacaa gagttctacc aggatgatga actcgggaag 200

 aagcagttca agtatgggaa ccagttggtt cggctggctc atcgggaaca 250

 ggtggctctg tatgtggacc tggacgacgt agccgaggat gaccccgagt 300

 tggtggactc aatttgtgag aatgccaggc gctacgcgaa gctctttgct 350

 gatgccgtac aagagctgct gcctcagtac aaggagaggg aagtggtaaa 400

 taaagatgtc ctggacgttt acattgagca tcggctaatg atggagcagc 450

 ggagtcggga ccctgggatg gtccgaagcc cccagaacca gtaccctgct 500

 gaactcatgc gcagatttga gctgtatttt caaggcccta gcagcagcaa 550

 gcctcgtgtg atccgggaag tgcgggctga ctctgtgggg aagttggtaa 600

 ctgtgcgtgg aatcgtcact cgtgtctctg aagtcaaacc caagatggtg 650

 gtggccactt acacttgtga ccagtgtggg gcagagacct accagccgat 700

 ccagtctccc actttcatgc ctctgatcat gtgcccaagc caggagtgcc 750

 aaaccaaccg ctcaggaggg cggctgtatc tgcagacacg gggctccaga 800

 ttcatcaaat tccaggagat gaagatgcaa gaacatagtg atcaggtgcc 850

 tgtgggaaat atccctcgta gtatcacggt gctggtagaa ggagagaaca 900

 caaggattgc ccagcctgga gaccacgtca gcgtcactgg tattttcttg 950

 ccaatcctgc gcactgggtt ccgacaggtg gtacagggtt tactctcaga 1000

 aacctacctg gaagcccatc ggattgtgaa gatgaacaag agtgaggatg 1050

 atgagtctgg ggctggagag ctcaccaggg aggagctgag gcaaattgca 1100

 gaggaggatt tctacgaaaa gctggcagct tcaatcgccc cagaaatata 1150

 cgggcatgaa gatgtgaaga aggcactgct gctcctgcta gtcgggggtg 1200

 tggaccagtc tcctcgaggc atgaaaatcc ggggcaacat caacatctgt 1250

 ctgatggggg atcctggtgt ggccaagtct cagctcctgt catacattga 1300

 tcgactggcg cctcgcagcc agtacacaac aggccggggc tcctcaggag 1350

 tggggcttac ggcagctgtg ctgagagact ccgtgagtgg agaactgacc 1400

 ttagagggtg gggccctggt gctggctgac cagggtgtgt gctgcattga 1450

 tgagttcgac aagatggctg aggccgaccg cacagccatc cacgaggtca 1500

 tggagcagca gaccatctcc attgccaagg ccggcattct caccacactc 1550

 aatgcccgct gctccatcct ggctgccgcc aaccctgcct acgggcgcta 1600

 caaccctcgc cgcagcctgg agcagaacat acagctacct gctgcactgc 1650

 tctcccggtt tgacctcctc tggctgattc aggaccggcc cgaccgagac 1700

 aatgacctac ggttggccca gcacatcacc tatgtgcacc agcacagccg 1750

 gcagcccccc tcccagtttg aacctctgga catgaagctc atgaggcgtt 1800

 acatagccat gtgccgcgag aagcagccca tggtgccaga gtctctggct 1850

 gactacatca cagcagcata cgtggagatg aggcgagagg cttgggctag 1900

 taaggatgcc acctatactt ctgcccggac cctgctggct atcctgcgcc 1950

 tttccactgc tctggcacgt ctgagaatgg tggatgtggt ggagaaagaa 2000

 gatgtgaatg aagccatcag gctaatggag atgtcaaagg actctcttct 2050

 aggagacaag gggcagacag ctaggactca gagaccagca gatgtgatat 2100

 ttgccaccgt ccgtgaactg gtctcagggg gccgaagtgt ccggttctct 2150

 gaggcagagc agcgctgtgt atctcgtggc ttcacacccg cccagttcca 2200

 ggcggctctg gatgaatatg aggagctcaa tgtctggcag gtcaatgctt 2250

 cccggacacg gatcactttt gtctgattcc agcctgcttg caaccctggg 2300

 gtcctcttgt tccctgctgg cctgcccctt gggaaggggc agtgatgcct 2350

 ttgaggggaa ggaggagccc ctctttctcc catgctgcac ttactccttt 2400

 tgctaataaa agtgtttgta gattgtc 2427

<210> 2330
<211> 719
<212> PRT
<213> Homo sapien

<400> 2330
 Met Ala Leu Lys Asp Tyr Ala Leu Glu Lys Glu Lys Val Lys Lys
   1               5                  10                  15

 Phe Leu Gln Glu Phe Tyr Gln Asp Asp Glu Leu Gly Lys Lys Gln
                  20                  25                  30

 Phe Lys Tyr Gly Asn Gln Leu Val Arg Leu Ala His Arg Glu Gln
                  35                  40                  45

 Val Ala Leu Tyr Val Asp Leu Asp Asp Val Ala Glu Asp Asp Pro
                  50                  55                  60

 Glu Leu Val Asp Ser Ile Cys Glu Asn Ala Arg Arg Tyr Ala Lys
                  65                  70                  75

 Leu Phe Ala Asp Ala Val Gln Glu Leu Leu Pro Gln Tyr Lys Glu
                  80                  85                  90

 Arg Glu Val Val Asn Lys Asp Val Leu Asp Val Tyr Ile Glu His
                  95                 100                 105

 Arg Leu Met Met Glu Gln Arg Ser Arg Asp Pro Gly Met Val Arg
                 110                 115                 120

 Ser Pro Gln Asn Gln Tyr Pro Ala Glu Leu Met Arg Arg Phe Glu
                 125                 130                 135

 Leu Tyr Phe Gln Gly Pro Ser Ser Ser Lys Pro Arg Val Ile Arg
                 140                 145                 150

 Glu Val Arg Ala Asp Ser Val Gly Lys Leu Val Thr Val Arg Gly
                 155                 160                 165

 Ile Val Thr Arg Val Ser Glu Val Lys Pro Lys Met Val Val Ala
                 170                 175                 180

 Thr Tyr Thr Cys Asp Gln Cys Gly Ala Glu Thr Tyr Gln Pro Ile
                 185                 190                 195

 Gln Ser Pro Thr Phe Met Pro Leu Ile Met Cys Pro Ser Gln Glu
                 200                 205                 210

 Cys Gln Thr Asn Arg Ser Gly Gly Arg Leu Tyr Leu Gln Thr Arg
                 215                 220                 225

 Gly Ser Arg Phe Ile Lys Phe Gln Glu Met Lys Met Gln Glu His
                 230                 235                 240

 Ser Asp Gln Val Pro Val Gly Asn Ile Pro Arg Ser Ile Thr Val
                 245                 250                 255

 Leu Val Glu Gly Glu Asn Thr Arg Ile Ala Gln Pro Gly Asp His
                 260                 265                 270

 Val Ser Val Thr Gly Ile Phe Leu Pro Ile Leu Arg Thr Gly Phe
                 275                 280                 285

 Arg Gln Val Val Gln Gly Leu Leu Ser Glu Thr Tyr Leu Glu Ala
                 290                 295                 300

 His Arg Ile Val Lys Met Asn Lys Ser Glu Asp Asp Glu Ser Gly
                 305                 310                 315

 Ala Gly Glu Leu Thr Arg Glu Glu Leu Arg Gln Ile Ala Glu Glu
                 320                 325                 330

 Asp Phe Tyr Glu Lys Leu Ala Ala Ser Ile Ala Pro Glu Ile Tyr
                 335                 340                 345

 Gly His Glu Asp Val Lys Lys Ala Leu Leu Leu Leu Leu Val Gly
                 350                 355                 360

 Gly Val Asp Gln Ser Pro Arg Gly Met Lys Ile Arg Gly Asn Ile
                 365                 370                 375

 Asn Ile Cys Leu Met Gly Asp Pro Gly Val Ala Lys Ser Gln Leu
                 380                 385                 390

 Leu Ser Tyr Ile Asp Arg Leu Ala Pro Arg Ser Gln Tyr Thr Thr
                 395                 400                 405

 Gly Arg Gly Ser Ser Gly Val Gly Leu Thr Ala Ala Val Leu Arg
                 410                 415                 420

 Asp Ser Val Ser Gly Glu Leu Thr Leu Glu Gly Gly Ala Leu Val
                 425                 430                 435

 Leu Ala Asp Gln Gly Val Cys Cys Ile Asp Glu Phe Asp Lys Met
                 440                 445                 450

 Ala Glu Ala Asp Arg Thr Ala Ile His Glu Val Met Glu Gln Gln
                 455                 460                 465

 Thr Ile Ser Ile Ala Lys Ala Gly Ile Leu Thr Thr Leu Asn Ala
                 470                 475                 480

 Arg Cys Ser Ile Leu Ala Ala Ala Asn Pro Ala Tyr Gly Arg Tyr
                 485                 490                 495

 Asn Pro Arg Arg Ser Leu Glu Gln Asn Ile Gln Leu Pro Ala Ala
                 500                 505                 510

 Leu Leu Ser Arg Phe Asp Leu Leu Trp Leu Ile Gln Asp Arg Pro
                 515                 520                 525

 Asp Arg Asp Asn Asp Leu Arg Leu Ala Gln His Ile Thr Tyr Val
                 530                 535                 540

 His Gln His Ser Arg Gln Pro Pro Ser Gln Phe Glu Pro Leu Asp
                 545                 550                 555

 Met Lys Leu Met Arg Arg Tyr Ile Ala Met Cys Arg Glu Lys Gln
                 560                 565                 570

 Pro Met Val Pro Glu Ser Leu Ala Asp Tyr Ile Thr Ala Ala Tyr
                 575                 580                 585

 Val Glu Met Arg Arg Glu Ala Trp Ala Ser Lys Asp Ala Thr Tyr
                 590                 595                 600

 Thr Ser Ala Arg Thr Leu Leu Ala Ile Leu Arg Leu Ser Thr Ala
                 605                 610                 615

 Leu Ala Arg Leu Arg Met Val Asp Val Val Glu Lys Glu Asp Val
                 620                 625                 630

 Asn Glu Ala Ile Arg Leu Met Glu Met Ser Lys Asp Ser Leu Leu
                 635                 640                 645

 Gly Asp Lys Gly Gln Thr Ala Arg Thr Gln Arg Pro Ala Asp Val
                 650                 655                 660

 Ile Phe Ala Thr Val Arg Glu Leu Val Ser Gly Gly Arg Ser Val
                 665                 670                 675

 Arg Phe Ser Glu Ala Glu Gln Arg Cys Val Ser Arg Gly Phe Thr
                 680                 685                 690

 Pro Ala Gln Phe Gln Ala Ala Leu Asp Glu Tyr Glu Glu Leu Asn
                 695                 700                 705

 Val Trp Gln Val Asn Ala Ser Arg Thr Arg Ile Thr Phe Val
                 710                 715

<210> 2331
<211> 1990
<212> DNA
<213> Homo sapien

<400> 2331
 gaattccggg ggtattggca gctgaggagt ggaggctggg cagctccgac 50

 tccctgacgc cagcgcgacc agatcaatcc aggctccagg agaaagcagg 100

 cgggcgggcg gagaaaggag aggccgagcg gctcaacccg ggccgaggct 150

 cggggagcgg agagtggcgc accgcccggc cgtccggacc cgggccgcga 200

 gaccccgctc gcccggccac tcgtgctccc gcacggacgg gcgcgccgcc 250

 aacccggtgc tgactgggtt acttttttaa acactaggaa tggtaatttc 300

 tactcttctg gacttcaaac taagaagtta aagagacttc tctgtaaata 350

 aacaaatctc ttctgctgtc cttttgcatt tggagacagc tttatttcac 400

 catatccaag gagtataact agtgctgtca ttatgaatgt gacaagttta 450

 ttttccttta caagtccagc tgtgaagaga cttcttgggt ggaaacaggg 500

 cgatgaagaa gaaaaatggg cagagaaagc tgttgatgct ttggtgaaaa 550

 aactgaagaa aaagaaaggt gccatggagg aactggaaaa ggccttgagc 600

 tgcccagggc aaccgagtaa ctgtgtcacc attccccgct ctctggatgg 650

 caggctgcaa gtctcccacc ggaagggact gcctcatgtc atttactgcc 700

 gtgtgtggcg ctggcccgat cttcagagcc accatgaact aaaaccactg 750

 gaatgctgtg agtttccttt tggttccaag cagaaggagg tctgcatcaa 800

 tccctaccac tataagagag tagaaagccc tgtacttcct cctgtgctgg 850

 ttccaagaca cagcgaatat aatcctcagc acagcctctt agctcagttc 900

 cgtaacttag gacaaaatga gcctcacatg ccactcaacg ccacttttcc 950

 agattctttc cagcaaccca acagccaccc gtttcctcac tctcccaata 1000

 gcagttaccc aaactctcct gggagcagca gcagcaccta ccctcactct 1050

 cccaccagct cagacccagg aagccctttc cagatgccag ctgatacgcc 1100

 cccacctgct tacctgcctc ctgaagaccc catgacccag gatggctctc 1150

 agccgatgga cacaaacatg atggcgcctc ccctgccctc agaaatcaac 1200

 agaggagatg ttcaggcggt tgcttatgag gaaccaaaac actggtgctc 1250

 tattgtctac tatgagctca acaatcgtgt gggtgaagcg ttccatgcct 1300

 cctccacaag tgtgttggtg gatggtttca ctgatccttc caacaataag 1350

 aaccgtttct gccttgggct gctctccaat gttaaccgga attccactat 1400

 tgaaaacacc aggcggcata ttggaaaagg agttcatctt tattatgttg 1450

 gaggggaggt gtatgccgaa tgccttagtg acagtagcat ctttgtgcaa 1500

 agtcggaact gcaactacca tcatggattt catcctacta ctgtttgcaa 1550

 gatccctagt gggtgtagtc tgaaaatttt taacaaccaa gaatttgctc 1600

 agttattggc acagtctgtg aaccatggat ttgagacagt ctatgagctt 1650

 acaaaaatgt gtactatacg tatgagcttt gtgaagggct ggggagcaga 1700

 ataccaccgc caggatgtta ctagcacccc ctgctggatt gagatacatc 1750

 tgcacggccc cctccagtgg ctggataaag ttcttactca aatgggttca 1800

 cctcataatc ctatttcatc tgtatcttaa atggccccag catctgcctc 1850

 tggaaaacta ttgagccttg catgtacttg aaggatggat gagtcagaca 1900

 cgattgagaa ctgacaaagg agccttgata atacttgacc tctgtgacca 1950

 actgttggat tcagaaattt aaacaaaaaa aaaaaaaaaa 1990

<210> 2332
<211> 465
<212> PRT
<213> Homo sapien

<400> 2332
 Met Asn Val Thr Ser Leu Phe Ser Phe Thr Ser Pro Ala Val Lys
   1               5                  10                  15

 Arg Leu Leu Gly Trp Lys Gln Gly Asp Glu Glu Glu Lys Trp Ala
                  20                  25                  30

 Glu Lys Ala Val Asp Ala Leu Val Lys Lys Leu Lys Lys Lys Lys
                  35                  40                  45

 Gly Ala Met Glu Glu Leu Glu Lys Ala Leu Ser Cys Pro Gly Gln
                  50                  55                  60

 Pro Ser Asn Cys Val Thr Ile Pro Arg Ser Leu Asp Gly Arg Leu
                  65                  70                  75

 Gln Val Ser His Arg Lys Gly Leu Pro His Val Ile Tyr Cys Arg
                  80                  85                  90

 Val Trp Arg Trp Pro Asp Leu Gln Ser His His Glu Leu Lys Pro
                  95                 100                 105

 Leu Glu Cys Cys Glu Phe Pro Phe Gly Ser Lys Gln Lys Glu Val
                 110                 115                 120

 Cys Ile Asn Pro Tyr His Tyr Lys Arg Val Glu Ser Pro Val Leu
                 125                 130                 135

 Pro Pro Val Leu Val Pro Arg His Ser Glu Tyr Asn Pro Gln His
                 140                 145                 150

 Ser Leu Leu Ala Gln Phe Arg Asn Leu Gly Gln Asn Glu Pro His
                 155                 160                 165

 Met Pro Leu Asn Ala Thr Phe Pro Asp Ser Phe Gln Gln Pro Asn
                 170                 175                 180

 Ser His Pro Phe Pro His Ser Pro Asn Ser Ser Tyr Pro Asn Ser
                 185                 190                 195

 Pro Gly Ser Ser Ser Ser Thr Tyr Pro His Ser Pro Thr Ser Ser
                 200                 205                 210

 Asp Pro Gly Ser Pro Phe Gln Met Pro Ala Asp Thr Pro Pro Pro
                 215                 220                 225

 Ala Tyr Leu Pro Pro Glu Asp Pro Met Thr Gln Asp Gly Ser Gln
                 230                 235                 240

 Pro Met Asp Thr Asn Met Met Ala Pro Pro Leu Pro Ser Glu Ile
                 245                 250                 255

 Asn Arg Gly Asp Val Gln Ala Val Ala Tyr Glu Glu Pro Lys His
                 260                 265                 270

 Trp Cys Ser Ile Val Tyr Tyr Glu Leu Asn Asn Arg Val Gly Glu
                 275                 280                 285

 Ala Phe His Ala Ser Ser Thr Ser Val Leu Val Asp Gly Phe Thr
                 290                 295                 300

 Asp Pro Ser Asn Asn Lys Asn Arg Phe Cys Leu Gly Leu Leu Ser
                 305                 310                 315

 Asn Val Asn Arg Asn Ser Thr Ile Glu Asn Thr Arg Arg His Ile
                 320                 325                 330

 Gly Lys Gly Val His Leu Tyr Tyr Val Gly Gly Glu Val Tyr Ala
                 335                 340                 345

 Glu Cys Leu Ser Asp Ser Ser Ile Phe Val Gln Ser Arg Asn Cys
                 350                 355                 360

 Asn Tyr His His Gly Phe His Pro Thr Thr Val Cys Lys Ile Pro
                 365                 370                 375

 Ser Gly Cys Ser Leu Lys Ile Phe Asn Asn Gln Glu Phe Ala Gln
                 380                 385                 390

 Leu Leu Ala Gln Ser Val Asn His Gly Phe Glu Thr Val Tyr Glu
                 395                 400                 405

 Leu Thr Lys Met Cys Thr Ile Arg Met Ser Phe Val Lys Gly Trp
                 410                 415                 420

 Gly Ala Glu Tyr His Arg Gln Asp Val Thr Ser Thr Pro Cys Trp
                 425                 430                 435

 Ile Glu Ile His Leu His Gly Pro Leu Gln Trp Leu Asp Lys Val
                 440                 445                 450

 Leu Thr Gln Met Gly Ser Pro His Asn Pro Ile Ser Ser Val Ser
                 455                 460                 465

<210> 2333
<211> 3242
<212> DNA
<213> Homo sapien

<400> 2333
 gagcagccaa aaggcccgcg gagtcgcgct gggccgcccc ggcgcagctg 50

 aaccgggggc cgcgcctgcc aggccgacgg gtctggccca gcctggcgcc 100

 aaggggttcg tgcgctgtgg agacgcggag ggtcgaggcg gcgcggcctg 150

 agtgaaaccc aatggaaaaa gcatgacatt tagaagtaga agacttagct 200

 tcaaatccct actccttcac ttactaattt tgtgatttgg aaatatccgc 250

 gcaagatgtt gacgttgcag acttggctag tgcaagcctt gtttattttc 300

 ctcaccactg aatctacagg tgaacttcta gatccatgtg gttatatcag 350

 tcctgaatct ccagttgtac aacttcattc taatttcact gcagtttgtg 400

 tgctaaagga aaaatgtatg gattattttc atgtaaatgc taattacatt 450

 gtctggaaaa caaaccattt tactattcct aaggagcaat atactatcat 500

 aaacagaaca gcatccagtg tcacctttac agatatagct tcattaaata 550

 ttcagctcac ttgcaacatt cttacattcg gacagcttga acagaatgtt 600

 tatggaatca caataatttc aggcttgcct ccagaaaaac ctaaaaattt 650

 gagttgcatt gtgaacgagg ggaagaaaat gaggtgtgag tgggatggtg 700

 gaagggaaac acacttggag acaaacttca ctttaaaatc tgaatgggca 750

 acacacaagt ttgctgattg caaagcaaaa cgtgacaccc ccacctcatg 800

 cactgttgat tattctactg tgtattttgt caacattgaa gtctgggtag 850

 aagcagagaa tgcccttggg aaggttacat cagatcatat caattttgat 900

 cctgtatata aagtgaagcc caatccgcca cataatttat cagtgatcaa 950

 ctcagaggaa ctgtctagta tcttaaaatt gacatggacc aacccaagta 1000

 ttaagagtgt tataatacta aaatataaca ttcaatatag gaccaaagat 1050

 gcctcaactt ggagccagat tcctcctgaa gacacagcat ccacccgatc 1100

 ttcattcact gtccaagacc ttaaaccttt tacagaatat gtgtttagga 1150

 ttcgctgtat gaaggaagat ggtaagggat actggagtga ctggagtgaa 1200

 gaagcaagtg ggatcaccta tgaagataga ccatctaaag caccaagttt 1250

 ctggtataaa atagatccat cccatactca aggctacaga actgtacaac 1300

 tcgtgtggaa gacattgcct ccttttgaag ccaatggaaa aatcttggat 1350

 tatgaagtga ctctcacaag atggaaatca catttacaaa attacacagt 1400

 taatgccaca aaactgacag taaatctcac aaatgatcgc tatctagcaa 1450

 ccctaacagt aagaaatctt gttggcaaat cagatgcagc tgttttaact 1500

 atccctgcct gtgactttca agctactcac cctgtaatgg atcttaaagc 1550

 attccccaaa gataacatgc tttgggtgga atggactact ccaagggaat 1600

 ctgtaaagaa atatatactt gagtggtgtg tgttatcaga taaagcaccc 1650

 tgtatcacag actggcaaca agaagatggt accgtgcatc gcacctattt 1700

 aagagggaac ttagcagaga gcaaatgcta tttgataaca gttactccag 1750

 tatatgctga tggaccagga agccctgaat ccataaaggc ataccttaaa 1800

 caagctccac cttccaaagg acctactgtt cggacaaaaa aagtagggaa 1850

 aaacgaagct gtcttagagt gggaccaact tcctgttgat gttcagaatg 1900

 gatttatcag aaattatact atattttata gaaccatcat tggaaatgaa 1950

 actgctgtga atgtggattc ttcccacaca gaatatacat tgtcctcttt 2000

 gactagtgac acattgtaca tggtacgaat ggcagcatac acagatgaag 2050

 gtgggaagga tggtccagaa ttcactttta ctaccccaaa gtttgctcaa 2100

 ggagaaattg aagccatagt cgtgcctgtt tgcttagcat tcctattgac 2150

 aactcttctg ggagtgctgt tctgctttaa taagcgagac ctaattaaaa 2200

 aacacatctg gcctaatgtt ccagatcctt caaagagtca tattgcccag 2250

 tggtcacctc acactcctcc aaggcacaat tttaattcaa aagatcaaat 2300

 gtattcagat ggcaatttca ctgatgtaag tgttgtggaa atagaagcaa 2350

 atgacaaaaa gccttttcca gaagatctga aatcattgga cctgttcaaa 2400

 aaggaaaaaa ttaatactga aggacacagc agtggtattg gggggtcttc 2450

 atgcatgtca tcttctaggc caagcatttc tagcagtgat gaaaatgaat 2500

 cttcacaaaa cacttcgagc actgtccagt attctaccgt ggtacacagt 2550

 ggctacagac accaagttcc gtcagtccaa gtcttctcaa gatccgagtc 2600

 tacccagccc ttgttagatt cagaggagcg gccagaagat ctacaattag 2650

 tagatcatgt agatggcggt gatggtattt tgcccaggca acagtacttc 2700

 aaacagaact gcagtcagca tgaatccagt ccagatattt cacattttga 2750

 aaggtcaaag caagtttcat cagtcaatga ggaagatttt gttagactta 2800

 aacagcagat ttcagatcat atttcacaat cctgtggatc tgggcaaatg 2850

 aaaatgtttc aggaagtttc tgcagcagat gcttttggtc caggtactga 2900

 gggacaagta gaaagatttg aaacagttgg catggaggct gcgactgatg 2950

 aaggcatgcc taaaagttac ttaccacaga ctgtacggca aggcggctac 3000

 atgcctcagt gaaggactag tagttcctgc tacaacttca gcagtaccta 3050

 taaagtaaag ctaaaatgat tttatctgtg aattcagatt ttaaaaagtc 3100

 ttcactctct gaagatgatc atttgccctt aaggacaaaa atgaactgaa 3150

 gtttcacatg agctatttcc attccagaat atctgggatt ctactttaag 3200

 cactacataa actgacttta tcctcagaaa aaaaaaaaaa aa 3242

<210> 2334
<211> 918
<212> PRT
<213> Homo sapien

<400> 2334
 Met Leu Thr Leu Gln Thr Trp Leu Val Gln Ala Leu Phe Ile Phe
   1               5                  10                  15

 Leu Thr Thr Glu Ser Thr Gly Glu Leu Leu Asp Pro Cys Gly Tyr
                  20                  25                  30

 Ile Ser Pro Glu Ser Pro Val Val Gln Leu His Ser Asn Phe Thr
                  35                  40                  45

 Ala Val Cys Val Leu Lys Glu Lys Cys Met Asp Tyr Phe His Val
                  50                  55                  60

 Asn Ala Asn Tyr Ile Val Trp Lys Thr Asn His Phe Thr Ile Pro
                  65                  70                  75

 Lys Glu Gln Tyr Thr Ile Ile Asn Arg Thr Ala Ser Ser Val Thr
                  80                  85                  90

 Phe Thr Asp Ile Ala Ser Leu Asn Ile Gln Leu Thr Cys Asn Ile
                  95                 100                 105

 Leu Thr Phe Gly Gln Leu Glu Gln Asn Val Tyr Gly Ile Thr Ile
                 110                 115                 120

 Ile Ser Gly Leu Pro Pro Glu Lys Pro Lys Asn Leu Ser Cys Ile
                 125                 130                 135

 Val Asn Glu Gly Lys Lys Met Arg Cys Glu Trp Asp Gly Gly Arg
                 140                 145                 150

 Glu Thr His Leu Glu Thr Asn Phe Thr Leu Lys Ser Glu Trp Ala
                 155                 160                 165

 Thr His Lys Phe Ala Asp Cys Lys Ala Lys Arg Asp Thr Pro Thr
                 170                 175                 180

 Ser Cys Thr Val Asp Tyr Ser Thr Val Tyr Phe Val Asn Ile Glu
                 185                 190                 195

 Val Trp Val Glu Ala Glu Asn Ala Leu Gly Lys Val Thr Ser Asp
                 200                 205                 210

 His Ile Asn Phe Asp Pro Val Tyr Lys Val Lys Pro Asn Pro Pro
                 215                 220                 225

 His Asn Leu Ser Val Ile Asn Ser Glu Glu Leu Ser Ser Ile Leu
                 230                 235                 240

 Lys Leu Thr Trp Thr Asn Pro Ser Ile Lys Ser Val Ile Ile Leu
                 245                 250                 255

 Lys Tyr Asn Ile Gln Tyr Arg Thr Lys Asp Ala Ser Thr Trp Ser
                 260                 265                 270

 Gln Ile Pro Pro Glu Asp Thr Ala Ser Thr Arg Ser Ser Phe Thr
                 275                 280                 285

 Val Gln Asp Leu Lys Pro Phe Thr Glu Tyr Val Phe Arg Ile Arg
                 290                 295                 300

 Cys Met Lys Glu Asp Gly Lys Gly Tyr Trp Ser Asp Trp Ser Glu
                 305                 310                 315

 Glu Ala Ser Gly Ile Thr Tyr Glu Asp Arg Pro Ser Lys Ala Pro
                 320                 325                 330

 Ser Phe Trp Tyr Lys Ile Asp Pro Ser His Thr Gln Gly Tyr Arg
                 335                 340                 345

 Thr Val Gln Leu Val Trp Lys Thr Leu Pro Pro Phe Glu Ala Asn
                 350                 355                 360

 Gly Lys Ile Leu Asp Tyr Glu Val Thr Leu Thr Arg Trp Lys Ser
                 365                 370                 375

 His Leu Gln Asn Tyr Thr Val Asn Ala Thr Lys Leu Thr Val Asn
                 380                 385                 390

 Leu Thr Asn Asp Arg Tyr Leu Ala Thr Leu Thr Val Arg Asn Leu
                 395                 400                 405

 Val Gly Lys Ser Asp Ala Ala Val Leu Thr Ile Pro Ala Cys Asp
                 410                 415                 420

 Phe Gln Ala Thr His Pro Val Met Asp Leu Lys Ala Phe Pro Lys
                 425                 430                 435

 Asp Asn Met Leu Trp Val Glu Trp Thr Thr Pro Arg Glu Ser Val
                 440                 445                 450

 Lys Lys Tyr Ile Leu Glu Trp Cys Val Leu Ser Asp Lys Ala Pro
                 455                 460                 465

 Cys Ile Thr Asp Trp Gln Gln Glu Asp Gly Thr Val His Arg Thr
                 470                 475                 480

 Tyr Leu Arg Gly Asn Leu Ala Glu Ser Lys Cys Tyr Leu Ile Thr
                 485                 490                 495

 Val Thr Pro Val Tyr Ala Asp Gly Pro Gly Ser Pro Glu Ser Ile
                 500                 505                 510

 Lys Ala Tyr Leu Lys Gln Ala Pro Pro Ser Lys Gly Pro Thr Val
                 515                 520                 525

 Arg Thr Lys Lys Val Gly Lys Asn Glu Ala Val Leu Glu Trp Asp
                 530                 535                 540

 Gln Leu Pro Val Asp Val Gln Asn Gly Phe Ile Arg Asn Tyr Thr
                 545                 550                 555

 Ile Phe Tyr Arg Thr Ile Ile Gly Asn Glu Thr Ala Val Asn Val
                 560                 565                 570

 Asp Ser Ser His Thr Glu Tyr Thr Leu Ser Ser Leu Thr Ser Asp
                 575                 580                 585

 Thr Leu Tyr Met Val Arg Met Ala Ala Tyr Thr Asp Glu Gly Gly
                 590                 595                 600

 Lys Asp Gly Pro Glu Phe Thr Phe Thr Thr Pro Lys Phe Ala Gln
                 605                 610                 615

 Gly Glu Ile Glu Ala Ile Val Val Pro Val Cys Leu Ala Phe Leu
                 620                 625                 630

 Leu Thr Thr Leu Leu Gly Val Leu Phe Cys Phe Asn Lys Arg Asp
                 635                 640                 645

 Leu Ile Lys Lys His Ile Trp Pro Asn Val Pro Asp Pro Ser Lys
                 650                 655                 660

 Ser His Ile Ala Gln Trp Ser Pro His Thr Pro Pro Arg His Asn
                 665                 670                 675

 Phe Asn Ser Lys Asp Gln Met Tyr Ser Asp Gly Asn Phe Thr Asp
                 680                 685                 690

 Val Ser Val Val Glu Ile Glu Ala Asn Asp Lys Lys Pro Phe Pro
                 695                 700                 705

 Glu Asp Leu Lys Ser Leu Asp Leu Phe Lys Lys Glu Lys Ile Asn
                 710                 715                 720

 Thr Glu Gly His Ser Ser Gly Ile Gly Gly Ser Ser Cys Met Ser
                 725                 730                 735

 Ser Ser Arg Pro Ser Ile Ser Ser Ser Asp Glu Asn Glu Ser Ser
                 740                 745                 750

 Gln Asn Thr Ser Ser Thr Val Gln Tyr Ser Thr Val Val His Ser
                 755                 760                 765

 Gly Tyr Arg His Gln Val Pro Ser Val Gln Val Phe Ser Arg Ser
                 770                 775                 780

 Glu Ser Thr Gln Pro Leu Leu Asp Ser Glu Glu Arg Pro Glu Asp
                 785                 790                 795

 Leu Gln Leu Val Asp His Val Asp Gly Gly Asp Gly Ile Leu Pro
                 800                 805                 810

 Arg Gln Gln Tyr Phe Lys Gln Asn Cys Ser Gln His Glu Ser Ser
                 815                 820                 825

 Pro Asp Ile Ser His Phe Glu Arg Ser Lys Gln Val Ser Ser Val
                 830                 835                 840

 Asn Glu Glu Asp Phe Val Arg Leu Lys Gln Gln Ile Ser Asp His
                 845                 850                 855

 Ile Ser Gln Ser Cys Gly Ser Gly Gln Met Lys Met Phe Gln Glu
                 860                 865                 870

 Val Ser Ala Ala Asp Ala Phe Gly Pro Gly Thr Glu Gly Gln Val
                 875                 880                 885

 Glu Arg Phe Glu Thr Val Gly Met Glu Ala Ala Thr Asp Glu Gly
                 890                 895                 900

 Met Pro Lys Ser Tyr Leu Pro Gln Thr Val Arg Gln Gly Gly Tyr
                 905                 910                 915

 Met Pro Gln


<210> 2335
<211> 1460
<212> DNA
<213> Homo sapien

<400> 2335
 accccatctt catctggcct tgactctgcc cttgaggggc ctaggggtgc 50

 agccagcctg ctccgagctc ccctgcagat ggaggaggcc atcctggtcc 100

 cctgcgtgct ggggctcctg ctgctgccca tcctggccat gttgatggca 150

 ctgtgtgtgc actgccacag actgccaggc tcctacgaca gcacatcctc 200

 agatagtttg tatccaaggg gcatccagtt caaacggcct cacacggttg 250

 ccccctggcc acctgcctac ccacctgtca cctcctaccc acccctgagc 300

 cagccagacc tgctccccat cccaagatcc ccgcagcccc ttgggggctc 350

 ccaccggacg ccatcttccc ggcgggattc tgatggtgcc aacagtgtgg 400

 cgagctacga gaacgagggt gcgtctggga tccgaggtgc ccaggctggg 450

 tggggagtct ggggtccgtc ctggactagg ctgacccctg tgtcgttacc 500

 cccagaacca gcctgtgagg atgcagatga ggatgaggac gactatcaca 550

 acccaggcta cctggtggtg cttcctgaca gcaccccggc cactagcact 600

 gctgccccat cagctcctgc actcagcacc cctggcatcc gagacagtgc 650

 cttctccatg gagtccattg atgattacgt gaacgttccg gagagcgggg 700

 agagcgcaga agcgtctctg gatggcagcc gggagtatgt gaatgtgtcc 750

 caggaactgc atcctggagc ggctaagact gagcctgccg ccctgagttc 800

 ccaggaggca gaggaagtgg aggaagaggg ggctccagat tacgagaatc 850

 tgcaggagct gaactgaggg cctgtggagg ccgagtctgt cctggaacca 900

 ggcttgcctg ggacggctga gctgggcagc tggaagtggc tctggggtcc 950

 tcacatggcg tcctgccctt gctccagcct gacaacagcc tgagaaatcc 1000

 ccccgtaact tattatcact ttggggttcg gcctgtgtcc cccgaacgct 1050

 ctgcaccttc tgacgcagcc tgagaatgac ctgccctggc cccagcccta 1100

 ctctgtgtaa tagaataaag gcctgcgtgt gtctgtgttg agcgtgcgtc 1150

 tgtgtgtgcc tgtgtgcgag tctgagtcag agatttggag atgtctctgt 1200

 gtgtttgtgt gtatctgtgg gtctccatcc tccatggggg ctcagccagg 1250

 tgctgtgaca ccccccttct gaatgaagcc ttctgacctg ggctggcact 1300

 gctgggggtg aggacacatt gccccatgag acagtcccag aacacggcag 1350

 ctgctggctg tgacaatggt ttcaccatcc ttagaccaag ggatgggacc 1400

 tgatgacctg ggaggactct tttagttctt acctcttgtg gttctcaata 1450

 aaacagaacg 1460

<210> 2336
<211> 262
<212> PRT
<213> Homo sapien

<400> 2336
 Met Glu Glu Ala Ile Leu Val Pro Cys Val Leu Gly Leu Leu Leu
   1               5                  10                  15

 Leu Pro Ile Leu Ala Met Leu Met Ala Leu Cys Val His Cys His
                  20                  25                  30

 Arg Leu Pro Gly Ser Tyr Asp Ser Thr Ser Ser Asp Ser Leu Tyr
                  35                  40                  45

 Pro Arg Gly Ile Gln Phe Lys Arg Pro His Thr Val Ala Pro Trp
                  50                  55                  60

 Pro Pro Ala Tyr Pro Pro Val Thr Ser Tyr Pro Pro Leu Ser Gln
                  65                  70                  75

 Pro Asp Leu Leu Pro Ile Pro Arg Ser Pro Gln Pro Leu Gly Gly
                  80                  85                  90

 Ser His Arg Thr Pro Ser Ser Arg Arg Asp Ser Asp Gly Ala Asn
                  95                 100                 105

 Ser Val Ala Ser Tyr Glu Asn Glu Gly Ala Ser Gly Ile Arg Gly
                 110                 115                 120

 Ala Gln Ala Gly Trp Gly Val Trp Gly Pro Ser Trp Thr Arg Leu
                 125                 130                 135

 Thr Pro Val Ser Leu Pro Pro Glu Pro Ala Cys Glu Asp Ala Asp
                 140                 145                 150

 Glu Asp Glu Asp Asp Tyr His Asn Pro Gly Tyr Leu Val Val Leu
                 155                 160                 165

 Pro Asp Ser Thr Pro Ala Thr Ser Thr Ala Ala Pro Ser Ala Pro
                 170                 175                 180

 Ala Leu Ser Thr Pro Gly Ile Arg Asp Ser Ala Phe Ser Met Glu
                 185                 190                 195

 Ser Ile Asp Asp Tyr Val Asn Val Pro Glu Ser Gly Glu Ser Ala
                 200                 205                 210

 Glu Ala Ser Leu Asp Gly Ser Arg Glu Tyr Val Asn Val Ser Gln
                 215                 220                 225

 Glu Leu His Pro Gly Ala Ala Lys Thr Glu Pro Ala Ala Leu Ser
                 230                 235                 240

 Ser Gln Glu Ala Glu Glu Val Glu Glu Glu Gly Ala Pro Asp Tyr
                 245                 250                 255

 Glu Asn Leu Gln Glu Leu Asn
                 260

<210> 2337
<211> 2391
<212> DNA
<213> Homo sapien

<400> 2337
 tgcggccgca cctgcaggcg cagagtaggt atggaagatc cctcgagatc 50

 cattgtgctc taaagccgcc gggggtccgt gtcctgtctc ggttggccgg 100

 acccgggccc gagcccgagc agtagccggc gccatgtcgg tggtgggcat 150

 agacctgggc ttccagagct gctacgtcgc tgtggcccgc gccggcggca 200

 tcgagactat cgctaatgag tatagcgacc gctgcacgcc ggcttgcatt 250

 tcttttggtc ctaagaatcg ttcaattgga gcagcagcta aaagccaggt 300

 aatttctaat gcaaagaaca cagtccaagg atttaaaaga ttccatggcc 350

 gagcattctc tgatccattt gtggaggcag aaaaatctaa ccttgcatat 400

 gatattgtgc agtggcctac aggattaaca ggtataaagg tgacatatat 450

 ggaggaagag cgaaatttta ccactgagca agtgactgcc atgcttttgt 500

 ccaaactgaa ggagacagcc gaaagtgttc ttaagaagcc tgtagttgac 550

 tgtgttgttt cggttccttg tttctatact gatgcagaaa gacgatcagt 600

 gatggatgca acacagattg ctggtcttaa ttgcttgcga ttaatgaatg 650

 aaaccactgc agttgctctt gcatatggaa tctataagca ggatcttcct 700

 cgcttagaag agaaaccaag aaatgtagtt tttgtagaca tgggccactc 750

 tgcttatcaa gtttctgtat gtgcatttaa tagaggaaaa ctgaaagttc 800

 tggccactgc atttgacacg acattgggag gtagaaaatt tgatgaagtg 850

 ttagtaaatc acttctgtga agaatttggg aagaaataca agctagacat 900

 taagtccaaa atccgtgcat tattacgact ctctcaggag tgtgagaaac 950

 tcaagaaatt gatgagtgca aatgcttcag atctcccttt gagcattgaa 1000

 tgttttatga atgatgttga tgtatctgga actatgaata gaggcaaatt 1050

 tctggagatg tgcaatgatc tcttagctag agtggagcca ccacttcgta 1100

 gtgttttgga acaaaccaag ttaaagaaag aagatattta tgcagtggag 1150

 atagttggtg gtgctacacg aatccctgcg gtaaaagaga agatcagcaa 1200

 atttttcggt aaagaactta gtacaacatt aaatgctgat gaagctgtca 1250

 ctcgaggctg tgcattgcag tgtgccatct tatcgcctgc tttcaaagtc 1300

 agagaatttt ctatcactga tgtagtacca tatccaatat ctctgagatg 1350

 gaattctcca gctgaagaag ggtcaagtga ctgtgaagtc ttttccaaaa 1400

 atcatgctgc tcctttctct aaagttctta cattttatag aaaggaacct 1450

 ttcactcttg aggcctacta cagctctcct caggatttgc cctatccaga 1500

 tcctgctata gctcagtttt cagttcagaa agtcactcct cagtctgatg 1550

 gctccagttc aaaagtgaaa gtcaaagttc gagtaaatgt ccatggcatt 1600

 ttcagtgtgt ccagtgcatc tttagtggag gttcacaagt ctgaggaaaa 1650

 tgaggagcca atggaaacag atcagaatgc aaaggaggaa gagaagatgc 1700

 aagtggacca ggaggaacca catgttgaag agcaacagca gcagacacca 1750

 gcagaaaata aggcagagtc tgaagaaatg gagacctctc aagctggatc 1800

 caaggataaa aagatggacc aaccacccca atgccaagaa ggcaaaagtg 1850

 aagaccagta ctgtggacct gccaatcgag aatcagctat atggcagata 1900

 gacagagaga tgctcaactt gtacattgaa aatgagggta agatgatcat 1950

 gcaggataaa ctggagaagg agcggaatga tgctaagaac gcagtggagg 2000

 aatatgtgta tgaaatgaga gacaagctta gtggtgaata tgagaagttt 2050

 gtgagtgaag atgatcgtaa cagttttact ttgaaactgg aagatactga 2100

 aaattggttg tatgaggatg gagaagacca gccaaagcaa gtttatgttg 2150

 ataagttggc tgaattaaaa aatctaggtc aacctattaa gatacgtttc 2200

 caggaatctg aagaacgacc aaattatttg aagaactaga gaacttaggg 2250

 aaacagatcc aacagtatat gaaaataatc agctcctttc aaaaacaagg 2300

 aggaccaggt atgatcattt ggatgctgct gacatgacaa aggtagaaaa 2350

 aagcacaaat gaagcaatgg agtggatgga agtcacacca a 2391

<210> 2338
<211> 701
<212> PRT
<213> Homo sapien

<400> 2338
 Met Ser Val Val Gly Ile Asp Leu Gly Phe Gln Ser Cys Tyr Val
   1               5                  10                  15

 Ala Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Tyr
                  20                  25                  30

 Ser Asp Arg Cys Thr Pro Ala Cys Ile Ser Phe Gly Pro Lys Asn
                  35                  40                  45

 Arg Ser Ile Gly Ala Ala Ala Lys Ser Gln Val Ile Ser Asn Ala
                  50                  55                  60

 Lys Asn Thr Val Gln Gly Phe Lys Arg Phe His Gly Arg Ala Phe
                  65                  70                  75

 Ser Asp Pro Phe Val Glu Ala Glu Lys Ser Asn Leu Ala Tyr Asp
                  80                  85                  90

 Ile Val Gln Trp Pro Thr Gly Leu Thr Gly Ile Lys Val Thr Tyr
                  95                 100                 105

 Met Glu Glu Glu Arg Asn Phe Thr Thr Glu Gln Val Thr Ala Met
                 110                 115                 120

 Leu Leu Ser Lys Leu Lys Glu Thr Ala Glu Ser Val Leu Lys Lys
                 125                 130                 135

 Pro Val Val Asp Cys Val Val Ser Val Pro Cys Phe Tyr Thr Asp
                 140                 145                 150

 Ala Glu Arg Arg Ser Val Met Asp Ala Thr Gln Ile Ala Gly Leu
                 155                 160                 165

 Asn Cys Leu Arg Leu Met Asn Glu Thr Thr Ala Val Ala Leu Ala
                 170                 175                 180

 Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Arg Leu Glu Glu Lys Pro
                 185                 190                 195

 Arg Asn Val Val Phe Val Asp Met Gly His Ser Ala Tyr Gln Val
                 200                 205                 210

 Ser Val Cys Ala Phe Asn Arg Gly Lys Leu Lys Val Leu Ala Thr
                 215                 220                 225

 Ala Phe Asp Thr Thr Leu Gly Gly Arg Lys Phe Asp Glu Val Leu
                 230                 235                 240

 Val Asn His Phe Cys Glu Glu Phe Gly Lys Lys Tyr Lys Leu Asp
                 245                 250                 255

 Ile Lys Ser Lys Ile Arg Ala Leu Leu Arg Leu Ser Gln Glu Cys
                 260                 265                 270

 Glu Lys Leu Lys Lys Leu Met Ser Ala Asn Ala Ser Asp Leu Pro
                 275                 280                 285

 Leu Ser Ile Glu Cys Phe Met Asn Asp Val Asp Val Ser Gly Thr
                 290                 295                 300

 Met Asn Arg Gly Lys Phe Leu Glu Met Cys Asn Asp Leu Leu Ala
                 305                 310                 315

 Arg Val Glu Pro Pro Leu Arg Ser Val Leu Glu Gln Thr Lys Leu
                 320                 325                 330

 Lys Lys Glu Asp Ile Tyr Ala Val Glu Ile Val Gly Gly Ala Thr
                 335                 340                 345

 Arg Ile Pro Ala Val Lys Glu Lys Ile Ser Lys Phe Phe Gly Lys
                 350                 355                 360

 Glu Leu Ser Thr Thr Leu Asn Ala Asp Glu Ala Val Thr Arg Gly
                 365                 370                 375

 Cys Ala Leu Gln Cys Ala Ile Leu Ser Pro Ala Phe Lys Val Arg
                 380                 385                 390

 Glu Phe Ser Ile Thr Asp Val Val Pro Tyr Pro Ile Ser Leu Arg
                 395                 400                 405

 Trp Asn Ser Pro Ala Glu Glu Gly Ser Ser Asp Cys Glu Val Phe
                 410                 415                 420

 Ser Lys Asn His Ala Ala Pro Phe Ser Lys Val Leu Thr Phe Tyr
                 425                 430                 435

 Arg Lys Glu Pro Phe Thr Leu Glu Ala Tyr Tyr Ser Ser Pro Gln
                 440                 445                 450

 Asp Leu Pro Tyr Pro Asp Pro Ala Ile Ala Gln Phe Ser Val Gln
                 455                 460                 465

 Lys Val Thr Pro Gln Ser Asp Gly Ser Ser Ser Lys Val Lys Val
                 470                 475                 480

 Lys Val Arg Val Asn Val His Gly Ile Phe Ser Val Ser Ser Ala
                 485                 490                 495

 Ser Leu Val Glu Val His Lys Ser Glu Glu Asn Glu Glu Pro Met
                 500                 505                 510

 Glu Thr Asp Gln Asn Ala Lys Glu Glu Glu Lys Met Gln Val Asp
                 515                 520                 525

 Gln Glu Glu Pro His Val Glu Glu Gln Gln Gln Gln Thr Pro Ala
                 530                 535                 540

 Glu Asn Lys Ala Glu Ser Glu Glu Met Glu Thr Ser Gln Ala Gly
                 545                 550                 555

 Ser Lys Asp Lys Lys Met Asp Gln Pro Pro Gln Cys Gln Glu Gly
                 560                 565                 570

 Lys Ser Glu Asp Gln Tyr Cys Gly Pro Ala Asn Arg Glu Ser Ala
                 575                 580                 585

 Ile Trp Gln Ile Asp Arg Glu Met Leu Asn Leu Tyr Ile Glu Asn
                 590                 595                 600

 Glu Gly Lys Met Ile Met Gln Asp Lys Leu Glu Lys Glu Arg Asn
                 605                 610                 615

 Asp Ala Lys Asn Ala Val Glu Glu Tyr Val Tyr Glu Met Arg Asp
                 620                 625                 630

 Lys Leu Ser Gly Glu Tyr Glu Lys Phe Val Ser Glu Asp Asp Arg
                 635                 640                 645

 Asn Ser Phe Thr Leu Lys Leu Glu Asp Thr Glu Asn Trp Leu Tyr
                 650                 655                 660

 Glu Asp Gly Glu Asp Gln Pro Lys Gln Val Tyr Val Asp Lys Leu
                 665                 670                 675

 Ala Glu Leu Lys Asn Leu Gly Gln Pro Ile Lys Ile Arg Phe Gln
                 680                 685                 690

 Glu Ser Glu Glu Arg Pro Asn Tyr Leu Lys Asn
                 695                 700

<210> 2339
<211> 715
<212> DNA
<213> Homo sapien

<400> 2339
 ggcacgaggg gccactgagc cggagccggc ctgagcagcg ctctcggttg 50

 cagtacccac tggaaggact taggcgctcg cgtggacacc gcaagcccct 100

 cagtagcctc ggcccaagag gcctgctttc cactcgctag ccccgccggg 150

 ggtccgtgtc ctgtctcggt ggccggaccc gggcccgagc ccgagcagta 200

 gccggcgcca tgtcggtggt gggcatagac ctgggcttcc agagctgcta 250

 cgtcgctgtg gcccgcgccg gcggcatcga gactatcgct aatgagtata 300

 gcgaccgctg cacgccggct tgcatttctt ttggtcctaa gaatcgttca 350

 attggagcag cagctaaaag ccaggtaatt tctaatgcaa agaacacagt 400

 ccaaggattt aaaagattcc atggccgagc attctctgat ccatttgtgg 450

 aggcagaaaa atctaacctt gcatatgata ttgtgcagtt gcctacagga 500

 ttaacaggta taaaggtgac atatatggag gaagagcaga atggaccagt 550

 ggatggacaa ggagacaacc caggccccca ggctgctgag cagggtacag 600

 acacagctgt gccttcggat tcagacaaga agcttcctga aatggacatt 650

 gattgattcc aacacttgtt tctattaaaa cagactatta taaaaaaaaa 700

 aaaaaaaaaa aaaaa 715

<210> 2340
<211> 148
<212> PRT
<213> Homo sapien

<400> 2340
 Met Ser Val Val Gly Ile Asp Leu Gly Phe Gln Ser Cys Tyr Val
   1               5                  10                  15

 Ala Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Tyr
                  20                  25                  30

 Ser Asp Arg Cys Thr Pro Ala Cys Ile Ser Phe Gly Pro Lys Asn
                  35                  40                  45

 Arg Ser Ile Gly Ala Ala Ala Lys Ser Gln Val Ile Ser Asn Ala
                  50                  55                  60

 Lys Asn Thr Val Gln Gly Phe Lys Arg Phe His Gly Arg Ala Phe
                  65                  70                  75

 Ser Asp Pro Phe Val Glu Ala Glu Lys Ser Asn Leu Ala Tyr Asp
                  80                  85                  90

 Ile Val Gln Leu Pro Thr Gly Leu Thr Gly Ile Lys Val Thr Tyr
                  95                 100                 105

 Met Glu Glu Glu Gln Asn Gly Pro Val Asp Gly Gln Gly Asp Asn
                 110                 115                 120

 Pro Gly Pro Gln Ala Ala Glu Gln Gly Thr Asp Thr Ala Val Pro
                 125                 130                 135

 Ser Asp Ser Asp Lys Lys Leu Pro Glu Met Asp Ile Asp
                 140                 145

<210> 2341
<211> 10330
<212> DNA
<213> Homo sapien

<400> 2341
 ctcggcccaa caaaatggcg gcggcagcgg tgtcgctttg tttccgcggc 50

 tcctgcggcg gtggcagtgg tagcggcctt tgagctgtgg ggaggttcca 100

 gcagcagcta cagtgacgac taagactcca gtgcatttct atcgtaaccg 150

 ggcgcggggg agcgcagatc ggcgcccagc aatcacagaa gccgacaagg 200

 cgttcaagcg aaaacatgac cgctgagccc atgagtgaaa gcaagttgaa 250

 tacattggtg cagaagcttc atgacttcct tgcacactca tcagaagaat 300

 ctgaagaaac aagttctcct ccacgacttg caatgaatca aaacacagat 350

 aaaatcagtg gttctggaag taactctgat atgatggaaa acagcaagga 400

 agagggaact agctcttcag aaaaatccaa gtcttcagga tcgtcacgat 450

 caaagaggaa accttcaatt gtaacaaagt atgtagaatc agatgatgaa 500

 aaacctttgg atgatgaaac tgtaaatgaa gatgcgtcta atgaaaattc 550

 agaaaatgat attactatgc agagcttgcc aaaaggtaca gtgattgtac 600

 agccagagcc agtgctgaat gaagacaaag atgattttaa agggcctgaa 650

 tttagaagca gaagtaaaat gaaaactgaa aatctcaaaa aacgcggaga 700

 agatgggctt catgggattg tgagctgcac tgcttgtgga caacaggtca 750

 atcattttca aaaagattcc atttatagac acccttcatt gcaagttctt 800

 atttgtaaga attgctttaa gtattacatg agtgatgata ttagccgtga 850

 ctcagatgga atggatgaac aatgtaggtg gtgtgcggaa ggtggaaact 900

 tgatttgttg tgacttttgc cataatgctt tctgcaagaa atgcattcta 950

 cgcaaccttg gtcgaaagga gttgtccaca ataatggatg aaaacaacca 1000

 atggtattgc tacatttgtc acccagagcc tttgttggac ttggtcactg 1050

 catgtaacag cgtatttgag aatttagaac agttgttgca gcaaaataag 1100

 aagaagataa aagttgacag tgaaaagagt aataaagtat atgaacatac 1150

 atccagattt tctccaaaga agactagttc aaattgtaat ggagaagaaa 1200

 agaaattaga tgattcctgt tctggctctg taacctactc ttattccgca 1250

 ctaattgtgc ccaaagagat gattaagaag gcaaaaaaac tgattgagac 1300

 cacagccaac atgaactcca gttatgttaa atttttaaag caggcaacag 1350

 ataattcaga aatcagttct gctacaaaat tacgtcagct taaggctttt 1400

 aagtctgtgt tggctgatat taagaaggct catcttgcat tggaagaaga 1450

 cttaaattcc gagtttcgag cgatggatgc tgtaaacaaa gagaaaaata 1500

 ccaaagagca taaagtcata gatgctaagt ttgaaacaaa agcacgaaaa 1550

 ggagaaaaac cttgtgcttt ggaaaagaag gatatttcaa agtcagaagc 1600

 taaactttca agaaaacagg tagatagtga gcacatgcat cagaatgttc 1650

 caacagagga acaaagaaca aataaaagta ccggtggtga acataagaaa 1700

 tctgatagaa aagaagaacc tcaatatgaa cctgccaaca cttctgaaga 1750

 tttagacatg gatattgtgt ctgttccttc ctcagttcca gaagacattt 1800

 ttgagaatct tgagactgct atggaagttc agagttcagt tgatcatcaa 1850

 ggggatggca gcagtggaac tgaacaagaa gtggagagtt catctgtaaa 1900

 attaaatatt tcttcaaaag acaacagagg aggtattaaa tcaaaaacta 1950

 cagctaaagt aacaaaagaa ttatatgtta aactcactcc tgtttccctt 2000

 tctaattccc caattaaagg tgctgattgt caggaagttc cacaagataa 2050

 agatggctat aaaagttgtg gtctgaaccc caagttagag aaatgtggac 2100

 ttggacagga aaacagtgat aatgagcatt tggttgaaaa tgaagtttca 2150

 ttacttttag aggaatctga tcttcgaaga tccccacgtg taaagactac 2200

 acccttgagg cgaccgacag aaactaaccc tgtaacatct aattcagatg 2250

 aagaatgtaa tgaaacagtt aaggagaaac aaaaactatc agttccagtg 2300

 agaaaaaagg ataagcgtaa ttcttctgac agtgctatag ataatcctaa 2350

 gcctaataaa ttgccaaaat ctaagcaatc agagactgtg gatcaaaatt 2400

 cagattctga tgaaatgcta gcaatcctca aagaggtgag caggatgagt 2450

 cacagttctt cttcagatac tgatattaat gaaattcata caaaccataa 2500

 gactttgtat gatttaaaga ctcaggcggg gaaagatgat aaaggaaaaa 2550

 ggaaacgaaa aagttctaca tctggctcag attttgatac taaaaagggc 2600

 aaatcagcta agagctctat aatttctaaa aagaaacgac aaacccagtc 2650

 tgagtcttct aattatgact cagaattaga aaaagagata aagagcatga 2700

 gtaaaattgg tgctgccaga accaccaaaa aaagaattcc aaatacaaaa 2750

 gattttgact cttctgaaga tgagaaacac agcaaaaaag gaatggataa 2800

 tcaagggcac aaaaatttga agacctcaca agaaggatca tctgatgatg 2850

 ctgaaagaaa acaagagaga gagactttct cttcagcaga aggcacagtt 2900

 gataaagaca cgaccatcat ggaattaaga gatcgacttc ctaagaagca 2950

 gcaagcaagt gcttccactg atggtgtcga taagctttct gggaaagagc 3000

 agagttttac ttctttggaa gttagaaaag ttgctgaaac taaagaaaag 3050

 agcaagcatc tcaaaaccaa aacatgtaaa aaagtacagg atggcttatc 3100

 tgatattgca gagaaattcc taaagaaaga ccagagcgat gaaacttctg 3150

 aagatgataa aaagcagagc aaaaagggaa ctgaagaaaa aaagaaacct 3200

 tcagacttta agaaaaaagt aattaaaatg gaacaacagt atgaatcttc 3250

 atctgatggc actgaaaagt tacctgagcg agaagaaatt tgtcattttc 3300

 ctaagggcat aaaacaaatt aagaatggaa caactgatgg agaaaagaaa 3350

 agtaaaaaaa taagagataa aacttctaaa aagaaggatg aattatctga 3400

 ttatgctgag aagtcaacag ggaaaggaga tagttgtgac tcttcagagg 3450

 ataaaaagag taagaatgga gcatatggta gagagaagaa aaggtgcaag 3500

 ttgcttggaa agagttcaag gaagagacaa gattgttcat catctgatac 3550

 tgagaaatat tccatgaaag aagatggttg taactcttct gataagagac 3600

 tgaaaagaat agaattgagg gaaagaagaa atttaagttc aaagagaaat 3650

 actaaggaaa tacaaagtgg ctcatcatca tctgatgctg aggaaagttc 3700

 tgaagataat aaaaagaaga agcaaagaac ttcatctaaa aagaaggcag 3750

 tcattgtcaa ggagaaaaag agaaactccc taagaacaag cactaaaagg 3800

 aagcaagctg acattacatc ctcatcttct tctgatatag aagatgatga 3850

 tcagaattct ataggtgagg gaagcagcga tgaacagaaa attaagcctg 3900

 tgactgaaaa tttagtgctg tcttcacata ctggattttg ccaatcttca 3950

 ggagatgaag ccttatctaa atcagtgcct gtcacagtgg atgatgatga 4000

 tgacgacaat gatcctgaga atagaattgc caagaagatg cttttagaag 4050

 aaattaaagc caatctttcc tctgatgagg atggatcttc agatgatgag 4100

 ccagaagaag ggaaaaaaag aactggaaaa caaaatgaag aaaacccagg 4150

 agatgaggaa gcaaaaaatc aagtcaattc tgaatcagat tcagattctg 4200

 aagaatctaa gaagccaaga tacagacata ggcttttgcg gcacaaattg 4250

 actgtgagtg acggagaatc tggagaagaa aaaaagacaa agcctaaaga 4300

 gcataaagaa gtcaaaggca gaaacagaag aaaggtgagc agtgaagatt 4350

 cagaagattc tgattttcag gaatcaggag ttagtgaaga agttagtgaa 4400

 tccgaagatg aacagcggcc cagaacaagg tctgcaaaga aagcagagtt 4450

 ggaagaaaat cagcggagct ataaacagaa aaagaaaagg cgacgtatta 4500

 aggttcaaga agattcatcc agtgaaaaca agagtaattc tgaggaagaa 4550

 gaggaggaaa aagaagagga ggaggaagag gaggaggagg aggaagagga 4600

 ggaggaagat gaaaatgatg attccaagtc tcctggaaaa ggcagaaaga 4650

 aaattcggaa gattcttaaa gatgataaac tgagaacaga aacacaaaat 4700

 gctcttaagg aagaggaaga gagacgaaaa cgtattgctg agagggagcg 4750

 tgagcgagaa aaattgagag aggtgataga aattgaagat gcttcaccca 4800

 ccaagtgtcc aataacaacc aagttggttt tagatgaaga tgaagaaacc 4850

 aaagaacctt tagtgcaggt tcatagaaat atggttatca aattgaaacc 4900

 ccatcaagta gatggtgttc agtttatgtg ggattgctgc tgtgagtctg 4950

 tgaaaaaaac aaagaaatct ccaggttcag gatgcattct tgcccactgt 5000

 atgggccttg gtaagacttt acaggtggta agttttcttc atacagttct 5050

 tttgtgtgac aaactggatt tcagcacggc gttagtggtt tgtcctctta 5100

 atactgcttt gaattggatg aatgaatttg agaagtggca agagggatta 5150

 aaagatgatg agaagcttga ggtttctgaa ttagcaactg tgaaacgtcc 5200

 tcaggagaga agctacatgc tgcagaggtg gcaagaagat ggtggtgtta 5250

 tgatcatagg ctatgagatg tatagaaatc ttgctcaagg aaggaatgtg 5300

 aagagtcgga aacttaaaga aatatttaac aaagctttgg ttgatccagg 5350

 ccctgatttt gttgtttgtg atgaaggcca tattctaaaa aatgaagcat 5400

 ctgctgtttc taaagctatg aattctatac gatcaaggag gaggattatt 5450

 ttaacaggaa caccacttca aaataaccta attgagtatc attgtatggt 5500

 taattttatc aaggaaaatt tacttggatc cattaaggag ttcaggaata 5550

 gatttataaa tccaattcaa aatggtcagt gtgcagattc taccatggta 5600

 gatgtcagag tgatgaaaaa acgtgctcac attctctatg agatgttagc 5650

 tggatgtgtt cagaggaaag attatacagc attaacaaaa ttcttgcctc 5700

 caaaacacga atatgtgtta gctgtgagaa tgacttctat tcagtgcaag 5750

 ctctatcagt actacttaga tcacttaaca ggtgtgggca ataatagtga 5800

 aggtggaaga ggaaaggcag gtgcaaagct tttccaagat tttcagatgt 5850

 taagtagaat atggactcat ccttggtgtt tgcagctaga ctacattagc 5900

 aaagaaaata agggttattt tgatgaagac agtatggatg aatttatagc 5950

 ctcagattct gatgaaacct ccatgagttt aagctccgat gattatacaa 6000

 aaaagaagaa aaaagggaaa aaggggaaaa aagatagtag ctcaagtgga 6050

 agtggcagtg acaatgatgt tgaagtgatt aaggtctgga attcaagatc 6100

 tcggggaggt ggtgaaggaa atgtggatga aacaggaaac aatccttctg 6150

 tttctttaaa actggaagaa agtaaagcta cttcttcttc taatccaagc 6200

 agcccagctc cagactggta caaagatttt gttacagatg ctgatgctga 6250

 ggttttagag cattctggga aaatggtact tctctttgaa attcttcgaa 6300

 tggcagagga aattggggat aaagtccttg ttttcagcca gtccctcata 6350

 tctctggact tgattgaaga ttttcttgaa ttagctagta gggagaagac 6400

 agaagataaa gataaacccc ttatttataa aggtgagggg aagtggcttc 6450

 gaaacattga ctattaccgt ttagatggtt ccactactgc acagtcaagg 6500

 aagaagtggg ctgaagaatt taatgatgaa actaatgtga gaggacgatt 6550

 atttatcatt tctactaaag caggatctct aggaattaat ctggtagctg 6600

 ctaatcgagt aattatattc gacgcttctt ggaatccatc ttatgacatc 6650

 cagagtatat tcagagttta tcgctttgga caaactaagc ctgtttatgt 6700

 atataggttc ttagctcagg gaaccatgga agataagatt tatgatcggc 6750

 aagtaactaa gcagtcactg tcttttcgag ttgttgatca gcagcaggtg 6800

 gagcgtcatt ttactatgaa tgagcttact gaactttata cttttgagcc 6850

 agacttatta gatgacccta attcagaaaa gaagaagaag agggatactc 6900

 ccatgctgcc aaaggatacc atacttgcag agctccttca gatacataaa 6950

 gaacacattg taggatacca tgaacatgat tctcttttgg accacaaaga 7000

 agaagaagag ttgactgaag aagaaagaaa agcagcttgg gctgagtatg 7050

 aagcagagaa gaagggactg accatgcgtt tcaacatacc aactgggacc 7100

 aatttacccc ctgtcagttt caactctcaa actccttata ttcctttcaa 7150

 tttgggagcc ctgtcagcaa tgagtaatca acagctggag gacctcatta 7200

 atcaaggaag agaaaaagtt gtagaagcaa caaacagtgt gacagcagtg 7250

 aggattcaac ctcttgagga tataatttca gctgtatgga aggagaacat 7300

 gaatctctca gaggcccaag tacaggcgtt agcattaagt agacaagcca 7350

 gccaggagct tgatgttaaa cgaagagaag caatctacaa tgatgtattg 7400

 acaaaacaac agatgttaat cagctgtgtt cagcgaatac ttatgaacag 7450

 aaggctccag cagcagtaca atcagcagca acagcaacaa atgacttatc 7500

 aacaagcaac actgggtcac ctcatgatgc caaagccccc aaatttgatc 7550

 atgaatcctt ctaactacca gcagattgat atgagaggaa tgtatcagcc 7600

 agtggctggt ggtatgcagc caccaccatt acagcgtgca ccacccccaa 7650

 tgagaagcaa aaatccagga ccttcccaag ggaaatcaat gtgattttgc 7700

 actaaaagct taatggattg ttaaaatcat agaaagatct tttatttctt 7750

 taggaatcaa tgacttaaca gaactcaact gtataaatag tttggtcccc 7800

 ttaaatgcca atcttccata ttagttttac tttttttttt ttttaaatag 7850

 ggcataccat ttcttcctga catttgtcag tgatgttgcc tagaatcttc 7900

 ttacacacgc tgagtacaga agatatttca aattgttttc agtgaaaaca 7950

 agtccttcca taatagtaac aactccacag atttcctctc taaattttta 8000

 tgcctgcttt tagcaaccat aaaattgtca taaaattaat aaatttagga 8050

 aagaataaag atttatatat tcattcttta catataaaaa cacacagctg 8100

 agttcttaga gttgattcct caagttatga aatacttttg tacttaatcc 8150

 atttcttgat taaagtgatt gaaatggttt taatgttctt ttgactgaag 8200

 tctgaaactg ggctcctgct ttattgtctc tgtgactgaa agttagaaac 8250

 tgagggttat ctttgacaca gaattgtgtg caatattctt aaatactact 8300

 gctctaaaag ttggagaagt cttgcagtta tcttagcatt gtataaacag 8350

 ccttaagtat agcctaagaa gagaattcct ttttcttctt tagtccttct 8400

 gccatttttt attttcagtt atatgtgctg aaataattac tggtaaaatt 8450

 tcagggttgt ggattatctt ccacacatga attttctctc tcctggcacg 8500

 aatataaagc acatctctta actgcatggt gccagtgcta atgcttcatc 8550

 ctgttgctgg cagtgggatg tggacttaga aaatcaagtt ctagcatttt 8600

 agtaggttaa cactgaagtt gtggttgtta ggttcacacc ctgttttata 8650

 aacaacatca aaatggcaga accattgctg actttaggtt cacatgagga 8700

 atgtactttt aacaattccc agtactatca gtattgtgaa ataattcctc 8750

 tgaaagataa gaatcactgg cttctatgcg cttcttttct ctcatcatca 8800

 tgttctttta ccccagtttc cttacatttt tttaaattgt ttcagagttt 8850

 gttttttttt tagtttagat tgtgaggcaa ttattaaatc aaaattaatt 8900

 catccaatac ccctttacta gaagttttac tagaaaatgt attacatttt 8950

 attttttctt aatccagttc tgcaaaaatg acctataaat ttattcatgt 9000

 acaattttgg ttacttgaat tgttaaagaa aacattgttt ttgactatgg 9050

 gagtcaactc aacatggcag aaccattttt gagatgatga tacaacaggt 9100

 agtgaaacag cttaagaatt ccaaaaaaaa aaaaaaaaaa aaaaaaaaag 9150

 aaaactgggt ttgggctttg ctttaggtat cactggatta gaatgagttt 9200

 aacattagct aaaactgctt tgagttgttt ggatgattaa gagattgcca 9250

 tttttatctt ggaagaacta gtggtaaaac atccaagagc actaggattg 9300

 tgatacagaa tttgtgaggt ttggtggatc cacgcccctc tcccccactt 9350

 tcccatgatg aaatatcact aataaatcct gtatatttag atattatgct 9400

 agccatgtaa tcagatttat ttaattgggt ggggcaggtg tgtatttact 9450

 ttagaaaaaa tgaaaaagac aagatttatg agaaatattt gaaggcagta 9500

 cactctggcc aactgttacc agttggtatt tctacaagtt cagaatattt 9550

 taaacctgat ttactagacc tgggaatttt caacatggtc taattattta 9600

 ctcaaagaca tagatgtgaa atttaggcaa ccttctaaat cttttcacca 9650

 tggatgaaac tataacttaa agataatact tagaagggtt aattggaaat 9700

 cagagtttga aataaaactt ggaccacttt gtatacactc ttctcacttg 9750

 acattttagc tatataatat gtactttgag tataacatca agctttaaca 9800

 aatatttaaa gacaaaaaaa tcacgtcagt aaaatactaa aaggctcatt 9850

 tttatatttg ttttagatgt tttaaatagt tgcaatggat taaaaatgat 9900

 gatttaaaat gttgcttgta atacagtttt gcctgctaaa ttctccacat 9950

 tttgtaacct gttttatttc tttgggtgta aagcgttttt gcttagtatt 10000

 gtgatattgt atatgttttg tcccagttgt atagtaatgt ttcagtccat 10050

 catccagctt tggctgctga aatcatacag ctgtgaagac ttgcctttgt 10100

 ttctgttaga ctgcttttca gttctgtatt gagtatctta agtactgtag 10150

 aaaagatgtc acttcttcct ttaaggctgt tttgtaatat atataaggac 10200

 tggaattgtg tttttaaaga aaagcattca agtatgacaa tatactatct 10250

 gtgttttcac cattcaaagt gctgtttagt agttgaaact taaactattt 10300

 aatgtcattt aataaagtga ccaaaatgtg 10330

<210> 2342
<211> 2000
<212> PRT
<213> Homo sapien

<400> 2342
 Met Thr Ala Glu Pro Met Ser Glu Ser Lys Leu Asn Thr Leu Val
   1               5                  10                  15

 Gln Lys Leu His Asp Phe Leu Ala His Ser Ser Glu Glu Ser Glu
                  20                  25                  30

 Glu Thr Ser Ser Pro Pro Arg Leu Ala Met Asn Gln Asn Thr Asp
                  35                  40                  45

 Lys Ile Ser Gly Ser Gly Ser Asn Ser Asp Met Met Glu Asn Ser
                  50                  55                  60

 Lys Glu Glu Gly Thr Ser Ser Ser Glu Lys Ser Lys Ser Ser Gly
                  65                  70                  75

 Ser Ser Arg Ser Lys Arg Lys Pro Ser Ile Val Thr Lys Tyr Val
                  80                  85                  90

 Glu Ser Asp Asp Glu Lys Pro Leu Asp Asp Glu Thr Val Asn Glu
                  95                 100                 105

 Asp Ala Ser Asn Glu Asn Ser Glu Asn Asp Ile Thr Met Gln Ser
                 110                 115                 120

 Leu Pro Lys Gly Thr Val Ile Val Gln Pro Glu Pro Val Leu Asn
                 125                 130                 135

 Glu Asp Lys Asp Asp Phe Lys Gly Pro Glu Phe Arg Ser Arg Ser
                 140                 145                 150

 Lys Met Lys Thr Glu Asn Leu Lys Lys Arg Gly Glu Asp Gly Leu
                 155                 160                 165

 His Gly Ile Val Ser Cys Thr Ala Cys Gly Gln Gln Val Asn His
                 170                 175                 180

 Phe Gln Lys Asp Ser Ile Tyr Arg His Pro Ser Leu Gln Val Leu
                 185                 190                 195

 Ile Cys Lys Asn Cys Phe Lys Tyr Tyr Met Ser Asp Asp Ile Ser
                 200                 205                 210

 Arg Asp Ser Asp Gly Met Asp Glu Gln Cys Arg Trp Cys Ala Glu
                 215                 220                 225

 Gly Gly Asn Leu Ile Cys Cys Asp Phe Cys His Asn Ala Phe Cys
                 230                 235                 240

 Lys Lys Cys Ile Leu Arg Asn Leu Gly Arg Lys Glu Leu Ser Thr
                 245                 250                 255

 Ile Met Asp Glu Asn Asn Gln Trp Tyr Cys Tyr Ile Cys His Pro
                 260                 265                 270

 Glu Pro Leu Leu Asp Leu Val Thr Ala Cys Asn Ser Val Phe Glu
                 275                 280                 285

 Asn Leu Glu Gln Leu Leu Gln Gln Asn Lys Lys Lys Ile Lys Val
                 290                 295                 300

 Asp Ser Glu Lys Ser Asn Lys Val Tyr Glu His Thr Ser Arg Phe
                 305                 310                 315

 Ser Pro Lys Lys Thr Ser Ser Asn Cys Asn Gly Glu Glu Lys Lys
                 320                 325                 330

 Leu Asp Asp Ser Cys Ser Gly Ser Val Thr Tyr Ser Tyr Ser Ala
                 335                 340                 345

 Leu Ile Val Pro Lys Glu Met Ile Lys Lys Ala Lys Lys Leu Ile
                 350                 355                 360

 Glu Thr Thr Ala Asn Met Asn Ser Ser Tyr Val Lys Phe Leu Lys
                 365                 370                 375

 Gln Ala Thr Asp Asn Ser Glu Ile Ser Ser Ala Thr Lys Leu Arg
                 380                 385                 390

 Gln Leu Lys Ala Phe Lys Ser Val Leu Ala Asp Ile Lys Lys Ala
                 395                 400                 405

 His Leu Ala Leu Glu Glu Asp Leu Asn Ser Glu Phe Arg Ala Met
                 410                 415                 420

 Asp Ala Val Asn Lys Glu Lys Asn Thr Lys Glu His Lys Val Ile
                 425                 430                 435

 Asp Ala Lys Phe Glu Thr Lys Ala Arg Lys Gly Glu Lys Pro Cys
                 440                 445                 450

 Ala Leu Glu Lys Lys Asp Ile Ser Lys Ser Glu Ala Lys Leu Ser
                 455                 460                 465

 Arg Lys Gln Val Asp Ser Glu His Met His Gln Asn Val Pro Thr
                 470                 475                 480

 Glu Glu Gln Arg Thr Asn Lys Ser Thr Gly Gly Glu His Lys Lys
                 485                 490                 495

 Ser Asp Arg Lys Glu Glu Pro Gln Tyr Glu Pro Ala Asn Thr Ser
                 500                 505                 510

 Glu Asp Leu Asp Met Asp Ile Val Ser Val Pro Ser Ser Val Pro
                 515                 520                 525

 Glu Asp Ile Phe Glu Asn Leu Glu Thr Ala Met Glu Val Gln Ser
                 530                 535                 540

 Ser Val Asp His Gln Gly Asp Gly Ser Ser Gly Thr Glu Gln Glu
                 545                 550                 555

 Val Glu Ser Ser Ser Val Lys Leu Asn Ile Ser Ser Lys Asp Asn
                 560                 565                 570

 Arg Gly Gly Ile Lys Ser Lys Thr Thr Ala Lys Val Thr Lys Glu
                 575                 580                 585

 Leu Tyr Val Lys Leu Thr Pro Val Ser Leu Ser Asn Ser Pro Ile
                 590                 595                 600

 Lys Gly Ala Asp Cys Gln Glu Val Pro Gln Asp Lys Asp Gly Tyr
                 605                 610                 615

 Lys Ser Cys Gly Leu Asn Pro Lys Leu Glu Lys Cys Gly Leu Gly
                 620                 625                 630

 Gln Glu Asn Ser Asp Asn Glu His Leu Val Glu Asn Glu Val Ser
                 635                 640                 645

 Leu Leu Leu Glu Glu Ser Asp Leu Arg Arg Ser Pro Arg Val Lys
                 650                 655                 660

 Thr Thr Pro Leu Arg Arg Pro Thr Glu Thr Asn Pro Val Thr Ser
                 665                 670                 675

 Asn Ser Asp Glu Glu Cys Asn Glu Thr Val Lys Glu Lys Gln Lys
                 680                 685                 690

 Leu Ser Val Pro Val Arg Lys Lys Asp Lys Arg Asn Ser Ser Asp
                 695                 700                 705

 Ser Ala Ile Asp Asn Pro Lys Pro Asn Lys Leu Pro Lys Ser Lys
                 710                 715                 720

 Gln Ser Glu Thr Val Asp Gln Asn Ser Asp Ser Asp Glu Met Leu
                 725                 730                 735

 Ala Ile Leu Lys Glu Val Ser Arg Met Ser His Ser Ser Ser Ser
                 740                 745                 750

 Asp Thr Asp Ile Asn Glu Ile His Thr Asn His Lys Thr Leu Tyr
                 755                 760                 765

 Asp Leu Lys Thr Gln Ala Gly Lys Asp Asp Lys Gly Lys Arg Lys
                 770                 775                 780

 Arg Lys Ser Ser Thr Ser Gly Ser Asp Phe Asp Thr Lys Lys Gly
                 785                 790                 795

 Lys Ser Ala Lys Ser Ser Ile Ile Ser Lys Lys Lys Arg Gln Thr
                 800                 805                 810

 Gln Ser Glu Ser Ser Asn Tyr Asp Ser Glu Leu Glu Lys Glu Ile
                 815                 820                 825

 Lys Ser Met Ser Lys Ile Gly Ala Ala Arg Thr Thr Lys Lys Arg
                 830                 835                 840

 Ile Pro Asn Thr Lys Asp Phe Asp Ser Ser Glu Asp Glu Lys His
                 845                 850                 855

 Ser Lys Lys Gly Met Asp Asn Gln Gly His Lys Asn Leu Lys Thr
                 860                 865                 870

 Ser Gln Glu Gly Ser Ser Asp Asp Ala Glu Arg Lys Gln Glu Arg
                 875                 880                 885

 Glu Thr Phe Ser Ser Ala Glu Gly Thr Val Asp Lys Asp Thr Thr
                 890                 895                 900

 Ile Met Glu Leu Arg Asp Arg Leu Pro Lys Lys Gln Gln Ala Ser
                 905                 910                 915

 Ala Ser Thr Asp Gly Val Asp Lys Leu Ser Gly Lys Glu Gln Ser
                 920                 925                 930

 Phe Thr Ser Leu Glu Val Arg Lys Val Ala Glu Thr Lys Glu Lys
                 935                 940                 945

 Ser Lys His Leu Lys Thr Lys Thr Cys Lys Lys Val Gln Asp Gly
                 950                 955                 960

 Leu Ser Asp Ile Ala Glu Lys Phe Leu Lys Lys Asp Gln Ser Asp
                 965                 970                 975

 Glu Thr Ser Glu Asp Asp Lys Lys Gln Ser Lys Lys Gly Thr Glu
                 980                 985                 990

 Glu Lys Lys Lys Pro Ser Asp Phe Lys Lys Lys Val Ile Lys Met
                 995                1000                1005

 Glu Gln Gln Tyr Glu Ser Ser Ser Asp Gly Thr Glu Lys Leu Pro
                1010                1015                1020

 Glu Arg Glu Glu Ile Cys His Phe Pro Lys Gly Ile Lys Gln Ile
                1025                1030                1035

 Lys Asn Gly Thr Thr Asp Gly Glu Lys Lys Ser Lys Lys Ile Arg
                1040                1045                1050

 Asp Lys Thr Ser Lys Lys Lys Asp Glu Leu Ser Asp Tyr Ala Glu
                1055                1060                1065

 Lys Ser Thr Gly Lys Gly Asp Ser Cys Asp Ser Ser Glu Asp Lys
                1070                1075                1080

 Lys Ser Lys Asn Gly Ala Tyr Gly Arg Glu Lys Lys Arg Cys Lys
                1085                1090                1095

 Leu Leu Gly Lys Ser Ser Arg Lys Arg Gln Asp Cys Ser Ser Ser
                1100                1105                1110

 Asp Thr Glu Lys Tyr Ser Met Lys Glu Asp Gly Cys Asn Ser Ser
                1115                1120                1125

 Asp Lys Arg Leu Lys Arg Ile Glu Leu Arg Glu Arg Arg Asn Leu
                1130                1135                1140

 Ser Ser Lys Arg Asn Thr Lys Glu Ile Gln Ser Gly Ser Ser Ser
                1145                1150                1155

 Ser Asp Ala Glu Glu Ser Ser Glu Asp Asn Lys Lys Lys Lys Gln
                1160                1165                1170

 Arg Thr Ser Ser Lys Lys Lys Ala Val Ile Val Lys Glu Lys Lys
                1175                1180                1185

 Arg Asn Ser Leu Arg Thr Ser Thr Lys Arg Lys Gln Ala Asp Ile
                1190                1195                1200

 Thr Ser Ser Ser Ser Ser Asp Ile Glu Asp Asp Asp Gln Asn Ser
                1205                1210                1215

 Ile Gly Glu Gly Ser Ser Asp Glu Gln Lys Ile Lys Pro Val Thr
                1220                1225                1230

 Glu Asn Leu Val Leu Ser Ser His Thr Gly Phe Cys Gln Ser Ser
                1235                1240                1245

 Gly Asp Glu Ala Leu Ser Lys Ser Val Pro Val Thr Val Asp Asp
                1250                1255                1260

 Asp Asp Asp Asp Asn Asp Pro Glu Asn Arg Ile Ala Lys Lys Met
                1265                1270                1275

 Leu Leu Glu Glu Ile Lys Ala Asn Leu Ser Ser Asp Glu Asp Gly
                1280                1285                1290

 Ser Ser Asp Asp Glu Pro Glu Glu Gly Lys Lys Arg Thr Gly Lys
                1295                1300                1305

 Gln Asn Glu Glu Asn Pro Gly Asp Glu Glu Ala Lys Asn Gln Val
                1310                1315                1320

 Asn Ser Glu Ser Asp Ser Asp Ser Glu Glu Ser Lys Lys Pro Arg
                1325                1330                1335

 Tyr Arg His Arg Leu Leu Arg His Lys Leu Thr Val Ser Asp Gly
                1340                1345                1350

 Glu Ser Gly Glu Glu Lys Lys Thr Lys Pro Lys Glu His Lys Glu
                1355                1360                1365

 Val Lys Gly Arg Asn Arg Arg Lys Val Ser Ser Glu Asp Ser Glu
                1370                1375                1380

 Asp Ser Asp Phe Gln Glu Ser Gly Val Ser Glu Glu Val Ser Glu
                1385                1390                1395

 Ser Glu Asp Glu Gln Arg Pro Arg Thr Arg Ser Ala Lys Lys Ala
                1400                1405                1410

 Glu Leu Glu Glu Asn Gln Arg Ser Tyr Lys Gln Lys Lys Lys Arg
                1415                1420                1425

 Arg Arg Ile Lys Val Gln Glu Asp Ser Ser Ser Glu Asn Lys Ser
                1430                1435                1440

 Asn Ser Glu Glu Glu Glu Glu Glu Lys Glu Glu Glu Glu Glu Glu
                1445                1450                1455

 Glu Glu Glu Glu Glu Glu Glu Glu Glu Asp Glu Asn Asp Asp Ser
                1460                1465                1470

 Lys Ser Pro Gly Lys Gly Arg Lys Lys Ile Arg Lys Ile Leu Lys
                1475                1480                1485

 Asp Asp Lys Leu Arg Thr Glu Thr Gln Asn Ala Leu Lys Glu Glu
                1490                1495                1500

 Glu Glu Arg Arg Lys Arg Ile Ala Glu Arg Glu Arg Glu Arg Glu
                1505                1510                1515

 Lys Leu Arg Glu Val Ile Glu Ile Glu Asp Ala Ser Pro Thr Lys
                1520                1525                1530

 Cys Pro Ile Thr Thr Lys Leu Val Leu Asp Glu Asp Glu Glu Thr
                1535                1540                1545

 Lys Glu Pro Leu Val Gln Val His Arg Asn Met Val Ile Lys Leu
                1550                1555                1560

 Lys Pro His Gln Val Asp Gly Val Gln Phe Met Trp Asp Cys Cys
                1565                1570                1575

 Cys Glu Ser Val Lys Lys Thr Lys Lys Ser Pro Gly Ser Gly Cys
                1580                1585                1590

 Ile Leu Ala His Cys Met Gly Leu Gly Lys Thr Leu Gln Val Val
                1595                1600                1605

 Ser Phe Leu His Thr Val Leu Leu Cys Asp Lys Leu Asp Phe Ser
                1610                1615                1620

 Thr Ala Leu Val Val Cys Pro Leu Asn Thr Ala Leu Asn Trp Met
                1625                1630                1635

 Asn Glu Phe Glu Lys Trp Gln Glu Gly Leu Lys Asp Asp Glu Lys
                1640                1645                1650

 Leu Glu Val Ser Glu Leu Ala Thr Val Lys Arg Pro Gln Glu Arg
                1655                1660                1665

 Ser Tyr Met Leu Gln Arg Trp Gln Glu Asp Gly Gly Val Met Ile
                1670                1675                1680

 Ile Gly Tyr Glu Met Tyr Arg Asn Leu Ala Gln Gly Arg Asn Val
                1685                1690                1695

 Lys Ser Arg Lys Leu Lys Glu Ile Phe Asn Lys Ala Leu Val Asp
                1700                1705                1710

 Pro Gly Pro Asp Phe Val Val Cys Asp Glu Gly His Ile Leu Lys
                1715                1720                1725

 Asn Glu Ala Ser Ala Val Ser Lys Ala Met Asn Ser Ile Arg Ser
                1730                1735                1740

 Arg Arg Arg Ile Ile Leu Thr Gly Thr Pro Leu Gln Asn Asn Leu
                1745                1750                1755

 Ile Glu Tyr His Cys Met Val Asn Phe Ile Lys Glu Asn Leu Leu
                1760                1765                1770

 Gly Ser Ile Lys Glu Phe Arg Asn Arg Phe Ile Asn Pro Ile Gln
                1775                1780                1785

 Asn Gly Gln Cys Ala Asp Ser Thr Met Val Asp Val Arg Val Met
                1790                1795                1800

 Lys Lys Arg Ala His Ile Leu Tyr Glu Met Leu Ala Gly Cys Val
                1805                1810                1815

 Gln Arg Lys Asp Tyr Thr Ala Leu Thr Lys Phe Leu Pro Pro Lys
                1820                1825                1830

 His Glu Tyr Val Leu Ala Val Arg Met Thr Ser Ile Gln Cys Lys
                1835                1840                1845

 Leu Tyr Gln Tyr Tyr Leu Asp His Leu Thr Gly Val Gly Asn Asn
                1850                1855                1860

 Ser Glu Gly Gly Arg Gly Lys Ala Gly Ala Lys Leu Phe Gln Asp
                1865                1870                1875

 Phe Gln Met Leu Ser Arg Ile Trp Thr His Pro Trp Cys Leu Gln
                1880                1885                1890

 Leu Asp Tyr Ile Ser Lys Glu Asn Lys Gly Tyr Phe Asp Glu Asp
                1895                1900                1905

 Ser Met Asp Glu Phe Ile Ala Ser Asp Ser Asp Glu Thr Ser Met
                1910                1915                1920

 Ser Leu Ser Ser Asp Asp Tyr Thr Lys Lys Lys Lys Lys Gly Lys
                1925                1930                1935

 Lys Gly Lys Lys Asp Ser Ser Ser Ser Gly Ser Gly Ser Asp Asn
                1940                1945                1950

 Asp Val Glu Val Ile Lys Val Trp Asn Ser Arg Ser Arg Gly Gly
                1955                1960                1965

 Gly Glu Gly Asn Val Asp Glu Thr Gly Asn Asn Pro Ser Val Ser
                1970                1975                1980

 Leu Lys Leu Glu Glu Ser Lys Ala Thr Ser Ser Ser Asn Pro Ser
                1985                1990                1995

 Ser Pro Ala Pro Asp
                2000

<210> 2343
<211> 1596
<212> DNA
<213> Homo sapien

<400> 2343
 tgtcggggac ggtaaccggg acccgtgctc tgctcctgtc gccttcgcct 50

 cctgaatccc tagccatatg cgtgagtgca tctccatcca cgttggccag 100

 gctggtgtcc agattggcaa tgcctgctgg gagctctact gcctggaaca 150

 cggcatccag cccgatggcc agatgccaag tgacaagacc attgggggag 200

 gagatgactc cttcaacacc ttcttcagtg agacgggcgc tggcaagcac 250

 gtgccccggg ctgtgtttgt agacttggaa cccacagtca ttgatgaagt 300

 tcgcactggc acctaccgcc agctcttcca ccctgagcag ctcatcacag 350

 gcaaggaaga tgctgccaat aactatgccc gagggcacta caccattggc 400

 aaggagatca ttgaccttgt gttggaccga attcgcaagc tggctgacca 450

 gtgcacccgt cttcagggct tcttggtttt ccacagcttt ggtgggggaa 500

 ctggttctgg gttcacctcc ctgctcatgg aacgcctgtc agttgattat 550

 ggcaagaaat ccaagctgga gttctccatt tacccggcac cccaggtttc 600

 cacagctgta gttgagccct acaactccat cctcaccacc cacaccaccc 650

 tggagcactc tgattgtgcc ttcatggtag acaatgaggc catctatgac 700

 atctgtcgta gaaacctcga tatcgagcgc ccaacctaca ctaaccttaa 750

 ccgccttatt agccagattg tgtcctccat cactgcttcc ctgagatttg 800

 atggagccct gaatgttgac ctgacagaat tccagaccaa cctggtcccc 850

 tacccccgca tccacttccc tctggccaca tatgcccctg tcatctctgc 900

 tgagaaagcc taccatgaac agctttctgt agcagacatc accaatgctt 950

 gctttgagcc agccaaccag atggtgaaat gtgaccctgg ccatggtaaa 1000

 tacatggctt gctgcctgtt gtaccgtggt gacgtggttc ccaaagatgt 1050

 caatgctgcc attgccacca tcaaaaccaa gcgcacgatc cagtttgtgg 1100

 attggtgccc cactggcttc aaggttggca tcaactacca gcctcccact 1150

 gtggtgcctg gtggagacct ggccaaggta cagagagctg tgtgcatgct 1200

 gagcaacacc acagccattg ctgaggcctg ggctcgcctg gaccacaagt 1250

 ttgacctgat gtatgccaag cgtgcctttg ttcactggta cgtgggtgag 1300

 gggatggagg aaggcgagtt ttcagaggcc cgtgaagata tggctgccct 1350

 tgagaaggat tatgaggagg ttggtgtgga ttctgttgaa ggagagggtg 1400

 aggaagaagg agaggaatac taattatcca ttccttttgg ccctgcagca 1450

 tgtcatgctc ccagaatttc agcttcagct taactgacag atgttaaagc 1500

 tttctggtta gattgttttc acttggtgat catgtctttt ccatgtgtac 1550

 ctgtaatatt tttccatcat atctcaaagt aaagtcatta acatca 1596

<210> 2344
<211> 451
<212> PRT
<213> Homo sapien

<400> 2344
 Met Arg Glu Cys Ile Ser Ile His Val Gly Gln Ala Gly Val Gln
   1               5                  10                  15

 Ile Gly Asn Ala Cys Trp Glu Leu Tyr Cys Leu Glu His Gly Ile
                  20                  25                  30

 Gln Pro Asp Gly Gln Met Pro Ser Asp Lys Thr Ile Gly Gly Gly
                  35                  40                  45

 Asp Asp Ser Phe Asn Thr Phe Phe Ser Glu Thr Gly Ala Gly Lys
                  50                  55                  60

 His Val Pro Arg Ala Val Phe Val Asp Leu Glu Pro Thr Val Ile
                  65                  70                  75

 Asp Glu Val Arg Thr Gly Thr Tyr Arg Gln Leu Phe His Pro Glu
                  80                  85                  90

 Gln Leu Ile Thr Gly Lys Glu Asp Ala Ala Asn Asn Tyr Ala Arg
                  95                 100                 105

 Gly His Tyr Thr Ile Gly Lys Glu Ile Ile Asp Leu Val Leu Asp
                 110                 115                 120

 Arg Ile Arg Lys Leu Ala Asp Gln Cys Thr Arg Leu Gln Gly Phe
                 125                 130                 135

 Leu Val Phe His Ser Phe Gly Gly Gly Thr Gly Ser Gly Phe Thr
                 140                 145                 150

 Ser Leu Leu Met Glu Arg Leu Ser Val Asp Tyr Gly Lys Lys Ser
                 155                 160                 165

 Lys Leu Glu Phe Ser Ile Tyr Pro Ala Pro Gln Val Ser Thr Ala
                 170                 175                 180

 Val Val Glu Pro Tyr Asn Ser Ile Leu Thr Thr His Thr Thr Leu
                 185                 190                 195

 Glu His Ser Asp Cys Ala Phe Met Val Asp Asn Glu Ala Ile Tyr
                 200                 205                 210

 Asp Ile Cys Arg Arg Asn Leu Asp Ile Glu Arg Pro Thr Tyr Thr
                 215                 220                 225

 Asn Leu Asn Arg Leu Ile Ser Gln Ile Val Ser Ser Ile Thr Ala
                 230                 235                 240

 Ser Leu Arg Phe Asp Gly Ala Leu Asn Val Asp Leu Thr Glu Phe
                 245                 250                 255

 Gln Thr Asn Leu Val Pro Tyr Pro Arg Ile His Phe Pro Leu Ala
                 260                 265                 270

 Thr Tyr Ala Pro Val Ile Ser Ala Glu Lys Ala Tyr His Glu Gln
                 275                 280                 285

 Leu Ser Val Ala Asp Ile Thr Asn Ala Cys Phe Glu Pro Ala Asn
                 290                 295                 300

 Gln Met Val Lys Cys Asp Pro Gly His Gly Lys Tyr Met Ala Cys
                 305                 310                 315

 Cys Leu Leu Tyr Arg Gly Asp Val Val Pro Lys Asp Val Asn Ala
                 320                 325                 330

 Ala Ile Ala Thr Ile Lys Thr Lys Arg Thr Ile Gln Phe Val Asp
                 335                 340                 345

 Trp Cys Pro Thr Gly Phe Lys Val Gly Ile Asn Tyr Gln Pro Pro
                 350                 355                 360

 Thr Val Val Pro Gly Gly Asp Leu Ala Lys Val Gln Arg Ala Val
                 365                 370                 375

 Cys Met Leu Ser Asn Thr Thr Ala Ile Ala Glu Ala Trp Ala Arg
                 380                 385                 390

 Leu Asp His Lys Phe Asp Leu Met Tyr Ala Lys Arg Ala Phe Val
                 395                 400                 405

 His Trp Tyr Val Gly Glu Gly Met Glu Glu Gly Glu Phe Ser Glu
                 410                 415                 420

 Ala Arg Glu Asp Met Ala Ala Leu Glu Lys Asp Tyr Glu Glu Val
                 425                 430                 435

 Gly Val Asp Ser Val Glu Gly Glu Gly Glu Glu Glu Gly Glu Glu
                 440                 445                 450

 Tyr


<210> 2345
<211> 1947
<212> DNA
<213> Homo sapien

<400> 2345
 ggcacgaggc caagagctac gcggcggcgg cggagcgcag gcctcgtgcc 50

 gttacggcca tcacggcggc cgcagtggcg tcctggagcc ctcctcagtg 100

 ctgaagctgc tgaaagatgg cagaagaagt ggtggtagta gccaaatttg 150

 attatgtggc ccaacaagaa caagagttgg acatcaagaa gaatgagaga 200

 ttatggcttc tggatgattc taagtcctgg tggcgagttc gaaattccat 250

 gaataaaaca ggttttgtgc cttctaacta tgtggaaagg aaaaacagtg 300

 ctcggaaagc atctattgtg aaaaacctaa aggatacctt aggcattgga 350

 aaagtgaaaa gaaaacctag tgtgccagat tctgcatctc ctgctgatga 400

 tagttttgtt gacccagggg aacgtctcta tgacctcaac atgcccgctt 450

 atgtgaaatt taactacatg gctgagagag aggatgaatt atcattgata 500

 aaggggacaa aggtgatcgt catggagaaa tgcagtgatg ggtggtggcg 550

 tggtagctac aatggacaag ttggatggtt cccttcaaac tatgtaactg 600

 aagaaggtga cagtcctttg ggtgaccatg tgggttctct gtcagagaaa 650

 ttagcagcag tcgtcaataa cctaaatact gggcaagtgt tgcatgtggt 700

 acaggctctt tacccattca gctcatctaa tgatgaagaa cttaatttcg 750

 agaaaggaga tgtaatggat gttattgaaa aacctgaaaa tgacccagag 800

 tggtggaaat gcaggaagat caatggtatg gttggtctag taccaaaaaa 850

 ctatgttacc gttatgcaga ataatccatt aacttcaggt ttggaaccat 900

 cacctccaca gtgtgattac attaggcctt cactcactgg aaagtttgct 950

 ggcaatcctt ggtattatgg caaagtcacc aggcatcaag cagaaatggc 1000

 attaaatgaa agaggacatg aaggggattt cctcattcgt gatagtgaat 1050

 cttcgccaaa tgatttctca gtatcactaa aagcacaagg gaaaaacaag 1100

 cattttaaag tccaactaaa agagactgtc tactgcattg ggcagcgtaa 1150

 attcagcacc atggaagaac ttgtagaaca ttacaaaaag gcaccaattt 1200

 ttacaagtga acaaggagaa aaattatatc ttgtcaagca tttatcatga 1250

 tactgctgac cagaagtgac tgctgtgtag ctgtaatttg tcatgtaatt 1300

 gaagactgag aaaatgttgg gtccagtcgt gcttgattgg aaattgttgt 1350

 ttctaaatct atatgagaat tgacaataag tatttttatt ataactcagc 1400

 ccatacatat atactatgta tgcagtgcat ctgcatagaa cagttcctta 1450

 tccttggcct tctgttttat tgtttttttc tttgctgttt tccctttgct 1500

 tctaatatta cagttttgta ttttgtaaac aaaaatcaaa taatgcatat 1550

 cagaatcttt atatggaaga aatcctttat tgcctttcct ttgtttcctt 1600

 gtaaaggcac cctgttctgt tatggttttt cattatataa aattattata 1650

 tctatatatg acatatgcta aaatttcttg gagagtgtta atcttttctg 1700

 tgactaaata gcaataataa gtggaaaatt agaaattatt tccaggtatt 1750

 atatttgtca caggccattg taaataccaa gtatattgtg tctgccataa 1800

 tttttaaaaa tacattcatt gtcttcagtc atacagcaag acacatgaga 1850

 catagattag aaaacatgtt gtacaatttt aatttacaac tgttggaaat 1900

 aaaaatcact taattttttt ccaaaaaaaa aaaaaaaaaa aaaaaaa 1947

<210> 2346
<211> 377
<212> PRT
<213> Homo sapien

<400> 2346
 Met Ala Glu Glu Val Val Val Val Ala Lys Phe Asp Tyr Val Ala
   1               5                  10                  15

 Gln Gln Glu Gln Glu Leu Asp Ile Lys Lys Asn Glu Arg Leu Trp
                  20                  25                  30

 Leu Leu Asp Asp Ser Lys Ser Trp Trp Arg Val Arg Asn Ser Met
                  35                  40                  45

 Asn Lys Thr Gly Phe Val Pro Ser Asn Tyr Val Glu Arg Lys Asn
                  50                  55                  60

 Ser Ala Arg Lys Ala Ser Ile Val Lys Asn Leu Lys Asp Thr Leu
                  65                  70                  75

 Gly Ile Gly Lys Val Lys Arg Lys Pro Ser Val Pro Asp Ser Ala
                  80                  85                  90

 Ser Pro Ala Asp Asp Ser Phe Val Asp Pro Gly Glu Arg Leu Tyr
                  95                 100                 105

 Asp Leu Asn Met Pro Ala Tyr Val Lys Phe Asn Tyr Met Ala Glu
                 110                 115                 120

 Arg Glu Asp Glu Leu Ser Leu Ile Lys Gly Thr Lys Val Ile Val
                 125                 130                 135

 Met Glu Lys Cys Ser Asp Gly Trp Trp Arg Gly Ser Tyr Asn Gly
                 140                 145                 150

 Gln Val Gly Trp Phe Pro Ser Asn Tyr Val Thr Glu Glu Gly Asp
                 155                 160                 165

 Ser Pro Leu Gly Asp His Val Gly Ser Leu Ser Glu Lys Leu Ala
                 170                 175                 180

 Ala Val Val Asn Asn Leu Asn Thr Gly Gln Val Leu His Val Val
                 185                 190                 195

 Gln Ala Leu Tyr Pro Phe Ser Ser Ser Asn Asp Glu Glu Leu Asn
                 200                 205                 210

 Phe Glu Lys Gly Asp Val Met Asp Val Ile Glu Lys Pro Glu Asn
                 215                 220                 225

 Asp Pro Glu Trp Trp Lys Cys Arg Lys Ile Asn Gly Met Val Gly
                 230                 235                 240

 Leu Val Pro Lys Asn Tyr Val Thr Val Met Gln Asn Asn Pro Leu
                 245                 250                 255

 Thr Ser Gly Leu Glu Pro Ser Pro Pro Gln Cys Asp Tyr Ile Arg
                 260                 265                 270

 Pro Ser Leu Thr Gly Lys Phe Ala Gly Asn Pro Trp Tyr Tyr Gly
                 275                 280                 285

 Lys Val Thr Arg His Gln Ala Glu Met Ala Leu Asn Glu Arg Gly
                 290                 295                 300

 His Glu Gly Asp Phe Leu Ile Arg Asp Ser Glu Ser Ser Pro Asn
                 305                 310                 315

 Asp Phe Ser Val Ser Leu Lys Ala Gln Gly Lys Asn Lys His Phe
                 320                 325                 330

 Lys Val Gln Leu Lys Glu Thr Val Tyr Cys Ile Gly Gln Arg Lys
                 335                 340                 345

 Phe Ser Thr Met Glu Glu Leu Val Glu His Tyr Lys Lys Ala Pro
                 350                 355                 360

 Ile Phe Thr Ser Glu Gln Gly Glu Lys Leu Tyr Leu Val Lys His
                 365                 370                 375

 Leu Ser


<210> 2347
<211> 1311
<212> DNA
<213> Homo sapien

<400> 2347
 ctctaccggc gggatttgat ggcgtgatgt ctcacagaaa gttctccgct 50

 cccagacatg ggtccctcgg cttcctgcct cggaagcgca gcagcaggca 100

 tcgtgggaag gtgaagagct tccctaagga tgacccgtcc aagccggtcc 150

 acctcacagc cttcctggga tacaaggctg gcatgactca catcgtgcgg 200

 gaagtcgaca ggccgggatc caaggtgaac aagaaggagg tggtggaggc 250

 tgtgaccatt gtagagacac cacccatggt ggttgtgggc attgtgggct 300

 acgtggaaac ccctcgaggc ctccggacct tcaagactgt ctttgctgag 350

 cacatcagtg atgaatgcaa gaggcgtttc tataagaatt ggcataaatc 400

 taagaagaag gcctttacca agtactgcaa gaaatggcag gatgaggatg 450

 gcaagaagca gctggagaag gacttcagca gcatgaagaa gtactgccaa 500

 gtcatccgtg tcattgccca cacccagatg cgcctgcttc ctctgcgcca 550

 gaagaaggcc cacctgatgg agatccaggt gaacggaggc actgtggccg 600

 agaagctgga ctgggcccgc gagaggcttg agcagcaggt acctgtgaac 650

 caagtgtttg ggcaggatga gatgatcgac gtcatcgggg tgaccaaggg 700

 caaaggctac aaaggggtca ccagtcgttg gcacaccaag aagctgcccc 750

 gcaagaccca ccgaggcctg cgcaaggtgg cctgtattgg ggcatggcat 800

 cctgctcgtg tagccttctc tgtggcacgc gctgggcaga aaggctacca 850

 tcaccgcact gagatcaaca agaagattta taagattggc cagggctacc 900

 ttatcaagga cggcaagctg atcaagaaca atgcctccac tgactatgac 950

 ctatctgaca agagcatcaa ccctctgggt ggctttgtcc actatggtga 1000

 agtgaccaat gactttgtca tgctgaaagg ctgtgtggtg ggaaccaaga 1050

 agcgggtgct caccctccgc aagtccttgc tggtgcagac gaagcggcgg 1100

 gctctggaga agattgacct taagttcatt gacaccacct ccaagtttgg 1150

 ccatggccgc ttccagacca tggaggagaa gaaagcattc atgggaccac 1200

 tgaagaaaga ccgaattgca aaggaagaag gagcttaatg ccaggaacag 1250

 attttgcagt tggtggggtc tcaataaaag ttattttcca ctgaaaaaaa 1300

 aaaaaaaaaa a 1311

<210> 2348
<211> 403
<212> PRT
<213> Homo sapien

<400> 2348
 Met Ser His Arg Lys Phe Ser Ala Pro Arg His Gly Ser Leu Gly
   1               5                  10                  15

 Phe Leu Pro Arg Lys Arg Ser Ser Arg His Arg Gly Lys Val Lys
                  20                  25                  30

 Ser Phe Pro Lys Asp Asp Pro Ser Lys Pro Val His Leu Thr Ala
                  35                  40                  45

 Phe Leu Gly Tyr Lys Ala Gly Met Thr His Ile Val Arg Glu Val
                  50                  55                  60

 Asp Arg Pro Gly Ser Lys Val Asn Lys Lys Glu Val Val Glu Ala
                  65                  70                  75

 Val Thr Ile Val Glu Thr Pro Pro Met Val Val Val Gly Ile Val
                  80                  85                  90

 Gly Tyr Val Glu Thr Pro Arg Gly Leu Arg Thr Phe Lys Thr Val
                  95                 100                 105

 Phe Ala Glu His Ile Ser Asp Glu Cys Lys Arg Arg Phe Tyr Lys
                 110                 115                 120

 Asn Trp His Lys Ser Lys Lys Lys Ala Phe Thr Lys Tyr Cys Lys
                 125                 130                 135

 Lys Trp Gln Asp Glu Asp Gly Lys Lys Gln Leu Glu Lys Asp Phe
                 140                 145                 150

 Ser Ser Met Lys Lys Tyr Cys Gln Val Ile Arg Val Ile Ala His
                 155                 160                 165

 Thr Gln Met Arg Leu Leu Pro Leu Arg Gln Lys Lys Ala His Leu
                 170                 175                 180

 Met Glu Ile Gln Val Asn Gly Gly Thr Val Ala Glu Lys Leu Asp
                 185                 190                 195

 Trp Ala Arg Glu Arg Leu Glu Gln Gln Val Pro Val Asn Gln Val
                 200                 205                 210

 Phe Gly Gln Asp Glu Met Ile Asp Val Ile Gly Val Thr Lys Gly
                 215                 220                 225

 Lys Gly Tyr Lys Gly Val Thr Ser Arg Trp His Thr Lys Lys Leu
                 230                 235                 240

 Pro Arg Lys Thr His Arg Gly Leu Arg Lys Val Ala Cys Ile Gly
                 245                 250                 255

 Ala Trp His Pro Ala Arg Val Ala Phe Ser Val Ala Arg Ala Gly
                 260                 265                 270

 Gln Lys Gly Tyr His His Arg Thr Glu Ile Asn Lys Lys Ile Tyr
                 275                 280                 285

 Lys Ile Gly Gln Gly Tyr Leu Ile Lys Asp Gly Lys Leu Ile Lys
                 290                 295                 300

 Asn Asn Ala Ser Thr Asp Tyr Asp Leu Ser Asp Lys Ser Ile Asn
                 305                 310                 315

 Pro Leu Gly Gly Phe Val His Tyr Gly Glu Val Thr Asn Asp Phe
                 320                 325                 330

 Val Met Leu Lys Gly Cys Val Val Gly Thr Lys Lys Arg Val Leu
                 335                 340                 345

 Thr Leu Arg Lys Ser Leu Leu Val Gln Thr Lys Arg Arg Ala Leu
                 350                 355                 360

 Glu Lys Ile Asp Leu Lys Phe Ile Asp Thr Thr Ser Lys Phe Gly
                 365                 370                 375

 His Gly Arg Phe Gln Thr Met Glu Glu Lys Lys Ala Phe Met Gly
                 380                 385                 390

 Pro Leu Lys Lys Asp Arg Ile Ala Lys Glu Glu Gly Ala
                 395                 400

<210> 2349
<211> 4064
<212> DNA
<213> Homo sapien

<400> 2349
 ccctctgacc aggactgagg ggctttttct ctctgtgccc caggcaagtt 50

 gcactcatta tggaattccg gcggcccgct aggcaagttg cactcatggc 100

 acctccaagt gaagagacgc ccctgatccc tcagcgttca tgcagcctct 150

 tgtccacgga ggctggtgcc ctgcatgtgc tgctgcccgc tcgggccccg 200

 gggccccccc agcgcctatc tttctccttt ggggaccact tggctgagga 250

 cctgtgcgtg caggctgcca aggccagcgg catcctgcct gtgtaccact 300

 ccctctttgc tctggccacg gaggacctgt cctgctggtt ccccccgagc 350

 cacatcttct ccgtggagga tgccagcacc caagtcctgc tgtacaggat 400

 tcgcttttac ttccccaatt ggtttgggct ggagaagtgc caccgcttcg 450

 ggctacgcaa ggatttggcc agtgctatcc ttgacctgcc agtcctggag 500

 cacctctttg cccagcaccg cagtgacctg gtgagtgggc gcctccccgt 550

 gggcctcagt ctcaaggagc agggtgagtg tctcagcctg gccgtgttgg 600

 acctggcccg gatggcgcga gagcaggccc agcggccggg agagctgctg 650

 aagactgtca gctacaaggc ctgcctaccc ccaagcctgc gcgacctgat 700

 ccagggcctg agcttcgtga cgcggagggc tattcggagg acggtgcgca 750

 gagccctgcc gcgcgtggcc gcctgccagg cagaccggca ctcgctcatg 800

 gccaagtaca tcatggacct ggagcggctg gatccagccg gggccgccga 850

 gaccttccac gtgggcctcc ctggggccct tggtggccac gacgggctgg 900

 ggctgctccg cgtggctggt gacggcggca tcgcctggac ccagggagaa 950

 caggaggtcc tccagccctt ctgcgacttt ccagaaatcg tagacattag 1000

 catcaagcag gccccgcgcg ttggcccggc cggagagcac cgcctggtca 1050

 ctgttaccag gacagacaac cagattttag aggccgagtt cccagggctg 1100

 cccgaggctc tgtcgttcgt ggcgctcgtg gacggctact tccggctgac 1150

 cacggactcc cagcacttct tctgcaagga ggtggcaccg ccgaggctgc 1200

 tggaggaagt ggccgagcag tgccacggcc ccatcactct ggactttgcc 1250

 atcaacaagc tcaagactgg gggctcacgt cctggctcct atgttctccg 1300

 ccgcagcccc caggactttg acagcttcct cctcactgtc tgtgtccaga 1350

 acccccttgg tcctgattat aagggctgcc tcatccggcg cagccccaca 1400

 ggaaccttcc ttctggttgg cctcagccga ccccacagca gtcttcgaga 1450

 gctcctggca acctgctggg atggggggct gcacgtagat ggggtggcag 1500

 tgaccctcac ttcctgctgt atccccagac ccaaagaaaa gtccaacctg 1550

 atcgtggtcc agagaggtca cagcccaccc acatcatcct tggttcagcc 1600

 ccaatcccaa taccagctga gtcagatgac atttcacaag atccctgctg 1650

 acagcctgga gtggcatgag aacctgggcc atgggtcctt caccaagatt 1700

 taccggggct gtcgccatga ggtggtggat ggggaggccc gaaagacaga 1750

 ggtgctgctg aaggtcatgg atgccaagca caagaactgc atggagtcat 1800

 tcctggaagc agcgagcttg atgagccaag tgtcgtaccg gcatctcgtg 1850

 ctgctccacg gcgtgtgcat ggctggagac agcaccatgg tgcaggaatt 1900

 tgtacacctg ggggccatag acatgtatct gcgaaaacgt ggccacctgg 1950

 tgccagccag ctggaagctg caggtggtca aacagctggc ctacgccctc 2000

 aactatctgg aggacaaagg cctgccccat ggcaatgtct ctgcccggaa 2050

 ggtgctcctg gctcgggagg gggctgatgg gagcccgccc ttcatcaagc 2100

 tgagtgaccc tggggtcagc cccgctgtgt taagcctgga gatgctcacc 2150

 gacaggatcc cctgggtggc ccccgagtgt ctccgggagg cgcagacact 2200

 tagcttggaa gctgacaagt ggggcttcgg cgccacggtc tgggaagtgt 2250

 ttagtggcgt caccatgccc atcagtgccc tggatcctgc taagaaactc 2300

 caattttatg aggaccggca gcagctgccg gcccccaagt ggacagagct 2350

 ggccctgctg attcaacagt gcatggccta tgagccggtc cagaggccct 2400

 ccttccgagc cgtcattcgt gacctcaata gcctcatctc ttcagactat 2450

 gagctcctct cagaccccac acctggtgcc ctggcacctc gtgatgggct 2500

 gtggaatggt gcccagctct atgcctgcca agaccccacg atcttcgagg 2550

 agagacacct caagtacatc tcacagctgg gcaagggcaa ctttggcagc 2600

 gtggagctgt gccgctatga cccgctagcc cacaatacag gtgccctggt 2650

 ggccgtgaaa cagctgcagc acagcgggcc agaccagcag agggactttc 2700

 agcgggagat tcagatcctc aaagcactgc acagtgattt cattgtcaag 2750

 tatcgtggtg tcagctatgg cccgggccgg ccagagctgc ggctggtcat 2800

 ggagtacctg cccagcggct gcttgcgcga cttcctgcag cggcaccgcg 2850

 cgcgcctcga tgccagccgc ctccttctct attcctcgca gatctgcaag 2900

 ggcatggagt acctgggctc ccgccgctgc gtgcaccgcg acctggccgc 2950

 ccgaaacatc ctcgtggaga gcgaggcaca cgtcaagatc gctgacttcg 3000

 gcctagctaa gctgctgccg cttgacaaag actactacgt ggtccgcgag 3050

 ccaggccaga gccccatttt ctggtatgcc cccgaatccc tctcggacaa 3100

 catcttctct cgccagtcag acgtctggag cttcggggtc gtcctgtacg 3150

 agctcttcac ctactgcgac aaaagctgca gcccctcggc cgagttcctg 3200

 cggatgatgg gatgtgagcg ggatgtcccc gccctctgcc gcctcttgga 3250

 actgctggag gagggccaga ggctgccggc gcctcctgcc tgccctgctg 3300

 aggttcacga gctcatgaag ctgtgctggg cccctagccc acaggaccgg 3350

 ccatcattca gcgccctggg cccccagctg gacatgctgt ggagcggaag 3400

 ccgggggtgt gagactcatg ccttcactgc tcacccagag ggcaaacacc 3450

 actccctgtc cttttcatag ctcctgcccg cagacctctg gattaggtct 3500

 ctgttgactg gctgtgtgac cttaggcccg gagctgcccc tctctgggcc 3550

 tcagaggcct tatgagggtc ctctacttca ggaacacccc catgacattg 3600

 catttggggg ggctcccgtg gcctgtagaa tagcctgtgg cctttgcaat 3650

 ttgttaaggt tcaagacaga tgggcatatg tgtcagtggg gctctctgag 3700

 tcctggccca aagaagcaag gaaccaaatt taagactctc gcatcttccc 3750

 aaccccttaa gccctggccc cctgagtttc cttttctcgt ctctctcttt 3800

 ttattttttt tatttttatt tttatttttg agacagagcc tcgctcgtta 3850

 cccagggtgg agtgcagtgg tagcgatctc ggctcacagt gcaacctctg 3900

 cttcccaggt tcaagcgatt ctcctgcctc agcctcccga gtagctggga 3950

 ttacaggtgt gcaccaccac acccggctaa ttttttttat ttttaataga 4000

 gatgaggttt caccatgatg gccaggctga tctcgaactc ctaacctcaa 4050

 gtgatcctcc cacc 4064

<210> 2350
<211> 1124
<212> PRT
<213> Homo sapien

<400> 2350
 Met Ala Pro Pro Ser Glu Glu Thr Pro Leu Ile Pro Gln Arg Ser
   1               5                  10                  15

 Cys Ser Leu Leu Ser Thr Glu Ala Gly Ala Leu His Val Leu Leu
                  20                  25                  30

 Pro Ala Arg Ala Pro Gly Pro Pro Gln Arg Leu Ser Phe Ser Phe
                  35                  40                  45

 Gly Asp His Leu Ala Glu Asp Leu Cys Val Gln Ala Ala Lys Ala
                  50                  55                  60

 Ser Gly Ile Leu Pro Val Tyr His Ser Leu Phe Ala Leu Ala Thr
                  65                  70                  75

 Glu Asp Leu Ser Cys Trp Phe Pro Pro Ser His Ile Phe Ser Val
                  80                  85                  90

 Glu Asp Ala Ser Thr Gln Val Leu Leu Tyr Arg Ile Arg Phe Tyr
                  95                 100                 105

 Phe Pro Asn Trp Phe Gly Leu Glu Lys Cys His Arg Phe Gly Leu
                 110                 115                 120

 Arg Lys Asp Leu Ala Ser Ala Ile Leu Asp Leu Pro Val Leu Glu
                 125                 130                 135

 His Leu Phe Ala Gln His Arg Ser Asp Leu Val Ser Gly Arg Leu
                 140                 145                 150

 Pro Val Gly Leu Ser Leu Lys Glu Gln Gly Glu Cys Leu Ser Leu
                 155                 160                 165

 Ala Val Leu Asp Leu Ala Arg Met Ala Arg Glu Gln Ala Gln Arg
                 170                 175                 180

 Pro Gly Glu Leu Leu Lys Thr Val Ser Tyr Lys Ala Cys Leu Pro
                 185                 190                 195

 Pro Ser Leu Arg Asp Leu Ile Gln Gly Leu Ser Phe Val Thr Arg
                 200                 205                 210

 Arg Ala Ile Arg Arg Thr Val Arg Arg Ala Leu Pro Arg Val Ala
                 215                 220                 225

 Ala Cys Gln Ala Asp Arg His Ser Leu Met Ala Lys Tyr Ile Met
                 230                 235                 240

 Asp Leu Glu Arg Leu Asp Pro Ala Gly Ala Ala Glu Thr Phe His
                 245                 250                 255

 Val Gly Leu Pro Gly Ala Leu Gly Gly His Asp Gly Leu Gly Leu
                 260                 265                 270

 Leu Arg Val Ala Gly Asp Gly Gly Ile Ala Trp Thr Gln Gly Glu
                 275                 280                 285

 Gln Glu Val Leu Gln Pro Phe Cys Asp Phe Pro Glu Ile Val Asp
                 290                 295                 300

 Ile Ser Ile Lys Gln Ala Pro Arg Val Gly Pro Ala Gly Glu His
                 305                 310                 315

 Arg Leu Val Thr Val Thr Arg Thr Asp Asn Gln Ile Leu Glu Ala
                 320                 325                 330

 Glu Phe Pro Gly Leu Pro Glu Ala Leu Ser Phe Val Ala Leu Val
                 335                 340                 345

 Asp Gly Tyr Phe Arg Leu Thr Thr Asp Ser Gln His Phe Phe Cys
                 350                 355                 360

 Lys Glu Val Ala Pro Pro Arg Leu Leu Glu Glu Val Ala Glu Gln
                 365                 370                 375

 Cys His Gly Pro Ile Thr Leu Asp Phe Ala Ile Asn Lys Leu Lys
                 380                 385                 390

 Thr Gly Gly Ser Arg Pro Gly Ser Tyr Val Leu Arg Arg Ser Pro
                 395                 400                 405

 Gln Asp Phe Asp Ser Phe Leu Leu Thr Val Cys Val Gln Asn Pro
                 410                 415                 420

 Leu Gly Pro Asp Tyr Lys Gly Cys Leu Ile Arg Arg Ser Pro Thr
                 425                 430                 435

 Gly Thr Phe Leu Leu Val Gly Leu Ser Arg Pro His Ser Ser Leu
                 440                 445                 450

 Arg Glu Leu Leu Ala Thr Cys Trp Asp Gly Gly Leu His Val Asp
                 455                 460                 465

 Gly Val Ala Val Thr Leu Thr Ser Cys Cys Ile Pro Arg Pro Lys
                 470                 475                 480

 Glu Lys Ser Asn Leu Ile Val Val Gln Arg Gly His Ser Pro Pro
                 485                 490                 495

 Thr Ser Ser Leu Val Gln Pro Gln Ser Gln Tyr Gln Leu Ser Gln
                 500                 505                 510

 Met Thr Phe His Lys Ile Pro Ala Asp Ser Leu Glu Trp His Glu
                 515                 520                 525

 Asn Leu Gly His Gly Ser Phe Thr Lys Ile Tyr Arg Gly Cys Arg
                 530                 535                 540

 His Glu Val Val Asp Gly Glu Ala Arg Lys Thr Glu Val Leu Leu
                 545                 550                 555

 Lys Val Met Asp Ala Lys His Lys Asn Cys Met Glu Ser Phe Leu
                 560                 565                 570

 Glu Ala Ala Ser Leu Met Ser Gln Val Ser Tyr Arg His Leu Val
                 575                 580                 585

 Leu Leu His Gly Val Cys Met Ala Gly Asp Ser Thr Met Val Gln
                 590                 595                 600

 Glu Phe Val His Leu Gly Ala Ile Asp Met Tyr Leu Arg Lys Arg
                 605                 610                 615

 Gly His Leu Val Pro Ala Ser Trp Lys Leu Gln Val Val Lys Gln
                 620                 625                 630

 Leu Ala Tyr Ala Leu Asn Tyr Leu Glu Asp Lys Gly Leu Pro His
                 635                 640                 645

 Gly Asn Val Ser Ala Arg Lys Val Leu Leu Ala Arg Glu Gly Ala
                 650                 655                 660

 Asp Gly Ser Pro Pro Phe Ile Lys Leu Ser Asp Pro Gly Val Ser
                 665                 670                 675

 Pro Ala Val Leu Ser Leu Glu Met Leu Thr Asp Arg Ile Pro Trp
                 680                 685                 690

 Val Ala Pro Glu Cys Leu Arg Glu Ala Gln Thr Leu Ser Leu Glu
                 695                 700                 705

 Ala Asp Lys Trp Gly Phe Gly Ala Thr Val Trp Glu Val Phe Ser
                 710                 715                 720

 Gly Val Thr Met Pro Ile Ser Ala Leu Asp Pro Ala Lys Lys Leu
                 725                 730                 735

 Gln Phe Tyr Glu Asp Arg Gln Gln Leu Pro Ala Pro Lys Trp Thr
                 740                 745                 750

 Glu Leu Ala Leu Leu Ile Gln Gln Cys Met Ala Tyr Glu Pro Val
                 755                 760                 765

 Gln Arg Pro Ser Phe Arg Ala Val Ile Arg Asp Leu Asn Ser Leu
                 770                 775                 780

 Ile Ser Ser Asp Tyr Glu Leu Leu Ser Asp Pro Thr Pro Gly Ala
                 785                 790                 795

 Leu Ala Pro Arg Asp Gly Leu Trp Asn Gly Ala Gln Leu Tyr Ala
                 800                 805                 810

 Cys Gln Asp Pro Thr Ile Phe Glu Glu Arg His Leu Lys Tyr Ile
                 815                 820                 825

 Ser Gln Leu Gly Lys Gly Asn Phe Gly Ser Val Glu Leu Cys Arg
                 830                 835                 840

 Tyr Asp Pro Leu Ala His Asn Thr Gly Ala Leu Val Ala Val Lys
                 845                 850                 855

 Gln Leu Gln His Ser Gly Pro Asp Gln Gln Arg Asp Phe Gln Arg
                 860                 865                 870

 Glu Ile Gln Ile Leu Lys Ala Leu His Ser Asp Phe Ile Val Lys
                 875                 880                 885

 Tyr Arg Gly Val Ser Tyr Gly Pro Gly Arg Pro Glu Leu Arg Leu
                 890                 895                 900

 Val Met Glu Tyr Leu Pro Ser Gly Cys Leu Arg Asp Phe Leu Gln
                 905                 910                 915

 Arg His Arg Ala Arg Leu Asp Ala Ser Arg Leu Leu Leu Tyr Ser
                 920                 925                 930

 Ser Gln Ile Cys Lys Gly Met Glu Tyr Leu Gly Ser Arg Arg Cys
                 935                 940                 945

 Val His Arg Asp Leu Ala Ala Arg Asn Ile Leu Val Glu Ser Glu
                 950                 955                 960

 Ala His Val Lys Ile Ala Asp Phe Gly Leu Ala Lys Leu Leu Pro
                 965                 970                 975

 Leu Asp Lys Asp Tyr Tyr Val Val Arg Glu Pro Gly Gln Ser Pro
                 980                 985                 990

 Ile Phe Trp Tyr Ala Pro Glu Ser Leu Ser Asp Asn Ile Phe Ser
                 995                1000                1005

 Arg Gln Ser Asp Val Trp Ser Phe Gly Val Val Leu Tyr Glu Leu
                1010                1015                1020

 Phe Thr Tyr Cys Asp Lys Ser Cys Ser Pro Ser Ala Glu Phe Leu
                1025                1030                1035

 Arg Met Met Gly Cys Glu Arg Asp Val Pro Ala Leu Cys Arg Leu
                1040                1045                1050

 Leu Glu Leu Leu Glu Glu Gly Gln Arg Leu Pro Ala Pro Pro Ala
                1055                1060                1065

 Cys Pro Ala Glu Val His Glu Leu Met Lys Leu Cys Trp Ala Pro
                1070                1075                1080

 Ser Pro Gln Asp Arg Pro Ser Phe Ser Ala Leu Gly Pro Gln Leu
                1085                1090                1095

 Asp Met Leu Trp Ser Gly Ser Arg Gly Cys Glu Thr His Ala Phe
                1100                1105                1110

 Thr Ala His Pro Glu Gly Lys His His Ser Leu Ser Phe Ser
                1115                1120

<210> 2351
<211> 1586
<212> DNA
<213> Homo sapien

<400> 2351
 gaatcaggaa gaccagctcc tcctactgtc ttctgtgtta cgggatcagc 50

 gttccttgtt gagtgggacc tgagttttga gagggtcttc tgctcctctt 100

 ggtctggtcc cttacttcca agagccccag agaggaaggc atgctgttgg 150

 ctctagctct gcttctagct ttcctgcctc ctgccagtca gaaatcttcc 200

 aacttggaag ggagaacaaa gtcagtcacc aggccaactg ggtcatcagc 250

 tgtaatcact tgtgatcttc ctgtagaaaa tgccgtctac acccactggt 300

 acctacacca ggaggggaag gccccacagc gtcttctgta ctatgactcc 350

 tacaactcca gggttgtgtt ggaatcagga atcagtcgag aaaagtatca 400

 tacttatgca agcacaggga agagccttaa atttatactg gaaaatctaa 450

 ttgaacgtga ctctggggtc tattactgtg ccacctggaa ggattattat 500

 aagaaactct ttggcagtgg aacaacactt gttgtcacag ataaacaact 550

 tgatgcagat gtttccccca agcccactat ttttcttcct tcgattgctg 600

 aaacaaaact ccagaaggct ggaacatatc tttgtcttct tgagaaattt 650

 ttcccagata ttattaagat acattggcaa gaaaagaaga gcaacacgat 700

 tctgggatcc caggagggga acaccatgaa gactaacgac acatacatga 750

 aatttagctg gttaacggtg ccagaagagt cactggacaa agaacacaga 800

 tgtatcgtca gacatgagaa taataaaaac ggaattgatc aagaaattat 850

 ctttcctcca ataaagacag atgtcaccac agtggatccc aaagacagtt 900

 attcaaaaga tgcaaatgat gtcaccacag tggatcccaa atacaattat 950

 tcaaaggatg caaatgatgt catcacaatg gatcccaaag acaattggtc 1000

 aaaagatgca aatgatacac tactgctgca gctcacaaac acctctgcat 1050

 attacatgta cctcctcctg ctcctcaaga gtgtggtcta ttttgccatc 1100

 atcacctgct gtctgcttgg aagaacggct ttctgctgca atggagagaa 1150

 atcataacag acggtggcac aaggaggcca tcttttcctc atcggttatt 1200

 gtccctagaa gcgtcttctg aggatctagt tgggctttct ttctgggttt 1250

 gggccatttc agttctcatg tgtgtactat tctatcatta ttgtataatg 1300

 gttttcaaac cagtgggcac acagagaacc tcagtctgta ataacaatga 1350

 ggaatagcca tggcgatctc cagcaccaat ctctccatgt tttccacagc 1400

 tcctccagcc aacccaaata gcgcctgcta tagtgtagac agcctgcggc 1450

 ttctagcctt gtccctctct tagtgttctt taatcagata actgcctgga 1500

 agcctttcat tttacacgcc ctgaagcagt cttctttgct agttgaatta 1550

 tgtggtgtgt ttttccgtaa taagcaaaat aaattt 1586

<210> 2352
<211> 338
<212> PRT
<213> Homo sapien

<400> 2352
 Met Leu Leu Ala Leu Ala Leu Leu Leu Ala Phe Leu Pro Pro Ala
   1               5                  10                  15

 Ser Gln Lys Ser Ser Asn Leu Glu Gly Arg Thr Lys Ser Val Thr
                  20                  25                  30

 Arg Pro Thr Gly Ser Ser Ala Val Ile Thr Cys Asp Leu Pro Val
                  35                  40                  45

 Glu Asn Ala Val Tyr Thr His Trp Tyr Leu His Gln Glu Gly Lys
                  50                  55                  60

 Ala Pro Gln Arg Leu Leu Tyr Tyr Asp Ser Tyr Asn Ser Arg Val
                  65                  70                  75

 Val Leu Glu Ser Gly Ile Ser Arg Glu Lys Tyr His Thr Tyr Ala
                  80                  85                  90

 Ser Thr Gly Lys Ser Leu Lys Phe Ile Leu Glu Asn Leu Ile Glu
                  95                 100                 105

 Arg Asp Ser Gly Val Tyr Tyr Cys Ala Thr Trp Lys Asp Tyr Tyr
                 110                 115                 120

 Lys Lys Leu Phe Gly Ser Gly Thr Thr Leu Val Val Thr Asp Lys
                 125                 130                 135

 Gln Leu Asp Ala Asp Val Ser Pro Lys Pro Thr Ile Phe Leu Pro
                 140                 145                 150

 Ser Ile Ala Glu Thr Lys Leu Gln Lys Ala Gly Thr Tyr Leu Cys
                 155                 160                 165

 Leu Leu Glu Lys Phe Phe Pro Asp Ile Ile Lys Ile His Trp Gln
                 170                 175                 180

 Glu Lys Lys Ser Asn Thr Ile Leu Gly Ser Gln Glu Gly Asn Thr
                 185                 190                 195

 Met Lys Thr Asn Asp Thr Tyr Met Lys Phe Ser Trp Leu Thr Val
                 200                 205                 210

 Pro Glu Glu Ser Leu Asp Lys Glu His Arg Cys Ile Val Arg His
                 215                 220                 225

 Glu Asn Asn Lys Asn Gly Ile Asp Gln Glu Ile Ile Phe Pro Pro
                 230                 235                 240

 Ile Lys Thr Asp Val Thr Thr Val Asp Pro Lys Asp Ser Tyr Ser
                 245                 250                 255

 Lys Asp Ala Asn Asp Val Thr Thr Val Asp Pro Lys Tyr Asn Tyr
                 260                 265                 270

 Ser Lys Asp Ala Asn Asp Val Ile Thr Met Asp Pro Lys Asp Asn
                 275                 280                 285

 Trp Ser Lys Asp Ala Asn Asp Thr Leu Leu Leu Gln Leu Thr Asn
                 290                 295                 300

 Thr Ser Ala Tyr Tyr Met Tyr Leu Leu Leu Leu Leu Lys Ser Val
                 305                 310                 315

 Val Tyr Phe Ala Ile Ile Thr Cys Cys Leu Leu Gly Arg Thr Ala
                 320                 325                 330

 Phe Cys Cys Asn Gly Glu Lys Ser
                 335

<210> 2353
<211> 3299
<212> DNA
<213> Homo sapien

<400> 2353
 ccacgcgtcc gtgcttttcc acagaaggtt agaccctgaa agagatggct 50

 cagcaccacc tatggatctt gctcctttgc ctgcaaacct ggccggaagc 100

 agctggaaaa gactcagaaa tcttcacagt gaatgggatt ctgggagagt 150

 cagtcacttt ccctgtaaat atccaagaac cacggcaagt taaaatcatt 200

 gcttggactt ctaaaacatc tgttgcttat gtaacaccag gagactcaga 250

 aacagcaccc gtagttactg tgacccacag aaattattat gaacggatac 300

 atgccttagg tccgaactac aatctggtca ttagcgatct gaggatggaa 350

 gacgcaggag actacaaagc agacataaat acacaggctg atccctacac 400

 caccaccaag cgctacaacc tgcaaatcta tcgtcggctt gggaaaccaa 450

 aaattacaca gagtttaatg gcatctgtga acagcacctg taatgtcaca 500

 ctgacatgct ctgtagagaa agaagaaaag aatgtgacat acaattggag 550

 tcccctggga gaagagggta atgtccttca aatcttccag actcctgagg 600

 accaagagct gacttacacg tgtacagccc agaaccctgt cagcaacaat 650

 tctgactcca tctctgcccg gcagctctgt gcagacatcg caatgggctt 700

 ccgtactcac cacaccgggt tgctgagcgt gctggctatg ttctttctgc 750

 ttgttctcat tctgtcttca gtgtttttgt tccgtttgtt caagagaaga 800

 caagatgctg cctcaaagaa aaccatatac acatatatca tggcttcaag 850

 gaacacccag ccagcagagt ccagaatcta tgatgaaatc ctgcagtcca 900

 aggtgcttcc ctccaaggaa gagccagtga acacagttta ttccgaagtg 950

 cagtttgctg ataagatggg gaaagccagc acacaggaca gtaaacctcc 1000

 tgggacttca agctatgaaa ttgtgatcta ggctgctggg ctgaattctc 1050

 cctctggaaa ctgagttaca accaccaata ctggcaggtt ccctggatcc 1100

 agatcttctc tgcccaactc ttactgggag attgcaaact gccacatctc 1150

 agcctgtaag caaagcagga aaccttctgc tgggcatagc ttgtgcctaa 1200

 atggacaaat ggatgcatac ccttcctgaa atgactccct tctgaatgaa 1250

 tgacaaagca ggttacctag tatagttttc ccaaacttct tcccatcata 1300

 gcacatgtag aaaataatat ttttatggca cactgggata aacaagcaag 1350

 attgctcact tctggaagct gcatatgact agaggcctct tgtgactgga 1400

 ggtaacaacc ctgcccagta actgtgggag aaggggatca atattttgca 1450

 cacctgtaat aggccatggc acaccagcca agatgctctg ctcacagtca 1500

 gtatgtgtga agatccctgg tgcgtggcct tcaccacgca tcttgagcaa 1550

 attaggaaaa tgtacccttc gcttgaggca gatgcagccc ttcccccgag 1600

 tgcatggctt ggagagcaga atgtgggctg catataagca cactcatccc 1650

 tttgtctggg aatctttgtg cagggcataa caggcttagt aagtccaaac 1700

 acagatgaca gtgctgtgtg ggtctctgtc agagttgtgg ctctcagcca 1750

 tgtagacaca ctctccaaat ggagtgttgg aaaatgttct ttctgcaggg 1800

 tctagagact gctgggacac ttttcttgga gtgctacttc agaagcctta 1850

 taggattttc tttctggcca agatttcctt ctgtatcact ccaagcagcc 1900

 tcagcagaag aagcagccat gcccagtatt cccactctcc aaaaggaact 1950

 gaccagctta tatttctcac acttctgggg aactgggtat aatccaacca 2000

 tcaaaataga agaccttgca agaagcagag tcattctcca gaaggaactt 2050

 gggagatgat ggtgcagatg atgaaactgg gttcatccca gttccaaaga 2100

 ctcagagaac tagagtttaa gctgaggcag agtgccgcca ccctggcatg 2150

 ccccacaaac agatcaccag ccagcttaca caggcattaa ctctcctcaa 2200

 tgaggaagaa tcattcacaa ctgagcaaga cattcatatg atcatttaag 2250

 gaagtgtttc ccttatgtgt tagcaagtat aatcggctaa ctcctaaatc 2300

 ccaatgaata gtcctaggct ggacagcaat gggctgcaat taggcagata 2350

 aagacatcag tcccagtaaa tgaatccata gactcatcta gcaccaacta 2400

 ccattagcac tatgttagga gctgcaaggc cccaaagtag aagatgtgca 2450

 taatgtctgc tcttgtgtag ctcaggagac aattccagca cagacactac 2500

 agttaacgct gaactgcagc tgcaagtaat agcatgaaca gtcagaaaaa 2550

 taccttatga gggggcaggg ctgaagctgg gccttgaagg atggatgaaa 2600

 tttggataga gaatgaggaa gacagagggc ctccaagtga gagaagcatg 2650

 aaaaatgagc aggggcctgg atcagtgggg tgtattcaga gcacctctcc 2700

 agatgcacca tgcatgctca cagtcccttg cctatgtgtg gcagagtgtc 2750

 ccagccagat gtgtgccccc accccatgtc catttacatg tccttcaatg 2800

 cccacctcaa aaggtacctc ttctgtaaag ctttccctgg tatcaggaat 2850

 caaaattaat cagggatctt ttcacactgc tgttttttcc tctttggtcc 2900

 ttctatcact aaaactcatc tcattcagcc ttacagcata actaattatt 2950

 tgttttcctc actacattgt acatgtggga attacagata aacggaagcc 3000

 ggctggggtg gtggctcacg cctgtaaccc caacactttg ggaggccaag 3050

 gcaggcggat cacctgaggt caggagttcg agattagtct ggccaacatg 3100

 gtgaaacccc atctctacta aaaatacgaa attagccagg tgtggtggca 3150

 cacatctgta gtcccagcta ctctggaggc tgagacagga gaatcgcttg 3200

 aacccaggaa gtggaggttg cagtgagctg agatcacacc actgcactcc 3250

 agcctgggag agagagagtg agtctccatc tcaaaaaaaa aaaaaaaaa 3299

<210> 2354
<211> 328
<212> PRT
<213> Homo sapien

<400> 2354
 Met Ala Gln His His Leu Trp Ile Leu Leu Leu Cys Leu Gln Thr
   1               5                  10                  15

 Trp Pro Glu Ala Ala Gly Lys Asp Ser Glu Ile Phe Thr Val Asn
                  20                  25                  30

 Gly Ile Leu Gly Glu Ser Val Thr Phe Pro Val Asn Ile Gln Glu
                  35                  40                  45

 Pro Arg Gln Val Lys Ile Ile Ala Trp Thr Ser Lys Thr Ser Val
                  50                  55                  60

 Ala Tyr Val Thr Pro Gly Asp Ser Glu Thr Ala Pro Val Val Thr
                  65                  70                  75

 Val Thr His Arg Asn Tyr Tyr Glu Arg Ile His Ala Leu Gly Pro
                  80                  85                  90

 Asn Tyr Asn Leu Val Ile Ser Asp Leu Arg Met Glu Asp Ala Gly
                  95                 100                 105

 Asp Tyr Lys Ala Asp Ile Asn Thr Gln Ala Asp Pro Tyr Thr Thr
                 110                 115                 120

 Thr Lys Arg Tyr Asn Leu Gln Ile Tyr Arg Arg Leu Gly Lys Pro
                 125                 130                 135

 Lys Ile Thr Gln Ser Leu Met Ala Ser Val Asn Ser Thr Cys Asn
                 140                 145                 150

 Val Thr Leu Thr Cys Ser Val Glu Lys Glu Glu Lys Asn Val Thr
                 155                 160                 165

 Tyr Asn Trp Ser Pro Leu Gly Glu Glu Gly Asn Val Leu Gln Ile
                 170                 175                 180

 Phe Gln Thr Pro Glu Asp Gln Glu Leu Thr Tyr Thr Cys Thr Ala
                 185                 190                 195

 Gln Asn Pro Val Ser Asn Asn Ser Asp Ser Ile Ser Ala Arg Gln
                 200                 205                 210

 Leu Cys Ala Asp Ile Ala Met Gly Phe Arg Thr His His Thr Gly
                 215                 220                 225

 Leu Leu Ser Val Leu Ala Met Phe Phe Leu Leu Val Leu Ile Leu
                 230                 235                 240

 Ser Ser Val Phe Leu Phe Arg Leu Phe Lys Arg Arg Gln Asp Ala
                 245                 250                 255

 Ala Ser Lys Lys Thr Ile Tyr Thr Tyr Ile Met Ala Ser Arg Asn
                 260                 265                 270

 Thr Gln Pro Ala Glu Ser Arg Ile Tyr Asp Glu Ile Leu Gln Ser
                 275                 280                 285

 Lys Val Leu Pro Ser Lys Glu Glu Pro Val Asn Thr Val Tyr Ser
                 290                 295                 300

 Glu Val Gln Phe Ala Asp Lys Met Gly Lys Ala Ser Thr Gln Asp
                 305                 310                 315

 Ser Lys Pro Pro Gly Thr Ser Ser Tyr Glu Ile Val Ile
                 320                 325

<210> 2355
<211> 1299
<212> DNA
<213> Homo sapien

<400> 2355
 cggctcaagt gaactgactc tgctagaaca gtgccgtgct tttccacaga 50

 aggttagacc ctgaaagaga tggctcagca ccacctatgg atcttgctcc 100

 tttgcctgca aacctggccg gaagcagctg gaaaagactc agaaatcttc 150

 acagtgaatg ggattctggg agagtcagtc actttccctg taaatatcca 200

 agaaccacgg caagttaaaa tcattgcttg gacttctaaa acatctgttg 250

 cttatgtaac accaggagac tcagaaacag cacccgtagt tactgtgacc 300

 cacagaaatt attatgaacg gatacatgcc ttaggtccga actacaatct 350

 ggtcattagc gatctgagga tggaagacgc aggagactac aaagcagaca 400

 taaatacaca ggctgatccc tacaccacca ccaagcgcta caacctgcaa 450

 atctatcgtc ggcttgggaa accaaaaatt acacagagtt taatggcatc 500

 tgtgaacagc acctgtaatg tcacactgac atgctctgta gagaaagaag 550

 aaaagaatgt gacatacaat tggagtcccc tgggagaaga gggtaatgtc 600

 cttcaaatct tccagactcc tgaggaccaa gagctgactt acacgtgtac 650

 agcccagaac cctgtcagca acaattctga ctccatctct gcccggcagc 700

 tctgtgcaga catcgcaatg ggcttccgta ctcaccacac cgggttgctg 750

 agcgtgctgg ctatgttctt tctgcttgtt ctcattctgt cttcagtgtt 800

 tttgttccgt ttgttcaaga gaagacaagg taggattttc ccagaaggta 850

 aaatgtggaa actcaccttc tctcctcctg ggactgaagc catttatcca 900

 aggtttagct gaaaggccca ttgttccagg gaatctgcct ttttccgatc 950

 tccaccccac cacctcccag aatgatggct ctgaggatgg tatgacatta 1000

 ccctgaatgg tcttcagaat ccattcctga gatcaccagt agctggtggg 1050

 cccagaacat gggttcgagc ttagtacata catgaacaag ctgtgcttca 1100

 ctgtacgagt gtgttcacct ttccgctcag ggccctcaca tgtgaaatgt 1150

 ttggactaga ggatctccag ggtcacttcc aatttcattg tattttgatt 1200

 atgactattg gagagtcatt gagaaacata tactaatcct gtactccatg 1250

 gttgtcacta tgtccctctg aatccctctg gatcattctg tagttgtgc 1299

<210> 2356
<211> 280
<212> PRT
<213> Homo sapien

<400> 2356
 Met Ala Gln His His Leu Trp Ile Leu Leu Leu Cys Leu Gln Thr
   1               5                  10                  15

 Trp Pro Glu Ala Ala Gly Lys Asp Ser Glu Ile Phe Thr Val Asn
                  20                  25                  30

 Gly Ile Leu Gly Glu Ser Val Thr Phe Pro Val Asn Ile Gln Glu
                  35                  40                  45

 Pro Arg Gln Val Lys Ile Ile Ala Trp Thr Ser Lys Thr Ser Val
                  50                  55                  60

 Ala Tyr Val Thr Pro Gly Asp Ser Glu Thr Ala Pro Val Val Thr
                  65                  70                  75

 Val Thr His Arg Asn Tyr Tyr Glu Arg Ile His Ala Leu Gly Pro
                  80                  85                  90

 Asn Tyr Asn Leu Val Ile Ser Asp Leu Arg Met Glu Asp Ala Gly
                  95                 100                 105

 Asp Tyr Lys Ala Asp Ile Asn Thr Gln Ala Asp Pro Tyr Thr Thr
                 110                 115                 120

 Thr Lys Arg Tyr Asn Leu Gln Ile Tyr Arg Arg Leu Gly Lys Pro
                 125                 130                 135

 Lys Ile Thr Gln Ser Leu Met Ala Ser Val Asn Ser Thr Cys Asn
                 140                 145                 150

 Val Thr Leu Thr Cys Ser Val Glu Lys Glu Glu Lys Asn Val Thr
                 155                 160                 165

 Tyr Asn Trp Ser Pro Leu Gly Glu Glu Gly Asn Val Leu Gln Ile
                 170                 175                 180

 Phe Gln Thr Pro Glu Asp Gln Glu Leu Thr Tyr Thr Cys Thr Ala
                 185                 190                 195

 Gln Asn Pro Val Ser Asn Asn Ser Asp Ser Ile Ser Ala Arg Gln
                 200                 205                 210

 Leu Cys Ala Asp Ile Ala Met Gly Phe Arg Thr His His Thr Gly
                 215                 220                 225

 Leu Leu Ser Val Leu Ala Met Phe Phe Leu Leu Val Leu Ile Leu
                 230                 235                 240

 Ser Ser Val Phe Leu Phe Arg Leu Phe Lys Arg Arg Gln Gly Arg
                 245                 250                 255

 Ile Phe Pro Glu Gly Lys Met Trp Lys Leu Thr Phe Ser Pro Pro
                 260                 265                 270

 Gly Thr Glu Ala Ile Tyr Pro Arg Phe Ser
                 275                 280

<210> 2357
<211> 2555
<212> DNA
<213> Homo sapien

<400> 2357
 ctctgagcgg cacttgcacc gggcagtgcc ccgctgctga ccaccatgct 50

 gatcgcttct tcctctgtgt cggggggctt ctgggtagag tttgtcctct 100

 cacttctgga gaagatgcag acacaggaga tcctgaggat actgcgactg 150

 cctgagctag gtgacttgga acagtttttc cgcagcctct cggccaccac 200

 cctcgtgagt atgggtgccc tggctgccat ccttgcctac tggttcactc 250

 agcggccaaa ggccttgcag ccgccatgca acctcctgat gcagtcagaa 300

 gaagtagagg acagtggcgg ggcacggcga tctgtgattg ggtctggccc 350

 tcagctactt acccactact atgatgatgc ccggaccatg taccaggtgt 400

 tccgccgtgg gcttagcatc tcagggaatg ggccctgtct tggtttcagg 450

 aagcctaagc agccttacca gtggctgtcc taccaggagg tggccgacag 500

 ggctgaattt ctggggtccg gacttctcca gcacaattgt aaagcatgca 550

 ctgatcagtt tattggtgtt tttgcacaaa atcggccaga gtggatcatt 600

 gtggagctgg cctgctacac atattccatg gtggtggtcc cgctctatga 650

 caccctgggc cctggggcta tccgctacat catcaataca gcggacatca 700

 gcaccgtgat tgtggacaaa cctcagaagg ctgtgcttct gctagagcat 750

 gtggagagga aggagactcc aggcctcaag ctgatcatcc tcatggaccc 800

 attcgaagaa gccctgaaag agagagggca gaagtgcggg gtggtcatta 850

 agtccatgca ggccgtggag gactgtggcc aagagaatca ccaggctcct 900

 gtgcccccgc agcctgatga cctctccatt gtgtgtttca caagcggcac 950

 gacagggaac ccaaaaggtg cgatgctcac ccatgggaac gtggtggctg 1000

 atttctcagg ctttctgaaa gtgacagaga gtcagtgggc tcccacttgt 1050

 gcggatgtgc acatttccta tttgccttta gcacacatgt ttgagcgaat 1100

 ggtgcagtct gtcgtctatt gccacggagg gcgtgttggc ttcttccagg 1150

 gagatatccg ccttctctca gatgacatga aggctctatg ccccaccatc 1200

 ttccctgtgg tcccacgact gctgaaccgg atgtacgaca agatcttcag 1250

 ccaggcaaac acaccattaa agcgctggct cctggagttt gcagcaaagc 1300

 gtaagcaagc cgaggtccgg agtggaatca tcaggaatga tagtatctgg 1350

 gatgaactct tctttaataa gattcaggcc agtcttggtg ggtgtgtgcg 1400

 gatgattgtt actggagcag ccccagcatc accaacagtt ctgggatttc 1450

 tccgggcagc tctagggtgc caggtttatg aaggttatgg ccaaactgag 1500

 tgcacagctg gatgtacctt caccactcct ggcgactgga cctcagggca 1550

 cgtaggggcg ccacttccct gcaatcatat caagctcgtt gatgttgagg 1600

 aactgaacta ctgggcctgc aaaggagagg gagagatatg tgtgagagga 1650

 ccaaatgtgt tcaaaggcta cttgaaagat ccagacagga cgaaggaggc 1700

 cctggacagc gatggctggc ttcacactgg agacatcgga aaatggctgc 1750

 cggcaggaac tcttaaaatt attgatcgga aaaagcatat atttaaactt 1800

 gctcagggag aatatgttgc acccgagaag attgagaaca tctacatccg 1850

 gagccaacct gtggcgcaaa tctatgtcca tggggacagc ttaaaggcct 1900

 ttttggtagg cattgttgtg cctgaccctg aagttatgcc ctcctgggcc 1950

 cagaagagag gaattgaagg aacatatgca gatctctgca caaataagga 2000

 tctgaagaaa gccattttgg aagatatggt gaggttagga aaagaaagtg 2050

 gactccattc ttttgagcag gttaaagcca ttcacatcca ttctgacatg 2100

 ttctcagttc aaaatggctt gctgacccca acactaaaag ctaagagacc 2150

 tgagctgaga gagtacttca aaaaacaaat agaagagctt tactcaatcc 2200

 ccatgtgaag ttcaaggaaa gttcttctca gtgtaatgaa ctgtctagca 2250

 atattatagt tattcttgaa agtaatgagt caaaatgaca cagctgaaaa 2300

 tgaataagca tctgatttta tgactgagcc ttttcctgtc ccaagaggtc 2350

 tttaacaata ttttctctat catcaatgag tatattttat ttttattata 2400

 aaaatgatat tgtggtggac tgctaaaaat atcacaaatg gcaatgtaaa 2450

 aatcaagaca ttttctcaag aacttgtacc actaaaagta atatattgtc 2500

 aatgttcaca gaactattaa actaaaaaaa aaaaaaaaaa aaaaaaaaaa 2550

 aaaaa 2555

<210> 2358
<211> 697
<212> PRT
<213> Homo sapien

<400> 2358
 Met Gln Thr Gln Glu Ile Leu Arg Ile Leu Arg Leu Pro Glu Leu
   1               5                  10                  15

 Gly Asp Leu Glu Gln Phe Phe Arg Ser Leu Ser Ala Thr Thr Leu
                  20                  25                  30

 Val Ser Met Gly Ala Leu Ala Ala Ile Leu Ala Tyr Trp Phe Thr
                  35                  40                  45

 Gln Arg Pro Lys Ala Leu Gln Pro Pro Cys Asn Leu Leu Met Gln
                  50                  55                  60

 Ser Glu Glu Val Glu Asp Ser Gly Gly Ala Arg Arg Ser Val Ile
                  65                  70                  75

 Gly Ser Gly Pro Gln Leu Leu Thr His Tyr Tyr Asp Asp Ala Arg
                  80                  85                  90

 Thr Met Tyr Gln Val Phe Arg Arg Gly Leu Ser Ile Ser Gly Asn
                  95                 100                 105

 Gly Pro Cys Leu Gly Phe Arg Lys Pro Lys Gln Pro Tyr Gln Trp
                 110                 115                 120

 Leu Ser Tyr Gln Glu Val Ala Asp Arg Ala Glu Phe Leu Gly Ser
                 125                 130                 135

 Gly Leu Leu Gln His Asn Cys Lys Ala Cys Thr Asp Gln Phe Ile
                 140                 145                 150

 Gly Val Phe Ala Gln Asn Arg Pro Glu Trp Ile Ile Val Glu Leu
                 155                 160                 165

 Ala Cys Tyr Thr Tyr Ser Met Val Val Val Pro Leu Tyr Asp Thr
                 170                 175                 180

 Leu Gly Pro Gly Ala Ile Arg Tyr Ile Ile Asn Thr Ala Asp Ile
                 185                 190                 195

 Ser Thr Val Ile Val Asp Lys Pro Gln Lys Ala Val Leu Leu Leu
                 200                 205                 210

 Glu His Val Glu Arg Lys Glu Thr Pro Gly Leu Lys Leu Ile Ile
                 215                 220                 225

 Leu Met Asp Pro Phe Glu Glu Ala Leu Lys Glu Arg Gly Gln Lys
                 230                 235                 240

 Cys Gly Val Val Ile Lys Ser Met Gln Ala Val Glu Asp Cys Gly
                 245                 250                 255

 Gln Glu Asn His Gln Ala Pro Val Pro Pro Gln Pro Asp Asp Leu
                 260                 265                 270

 Ser Ile Val Cys Phe Thr Ser Gly Thr Thr Gly Asn Pro Lys Gly
                 275                 280                 285

 Ala Met Leu Thr His Gly Asn Val Val Ala Asp Phe Ser Gly Phe
                 290                 295                 300

 Leu Lys Val Thr Glu Ser Gln Trp Ala Pro Thr Cys Ala Asp Val
                 305                 310                 315

 His Ile Ser Tyr Leu Pro Leu Ala His Met Phe Glu Arg Met Val
                 320                 325                 330

 Gln Ser Val Val Tyr Cys His Gly Gly Arg Val Gly Phe Phe Gln
                 335                 340                 345

 Gly Asp Ile Arg Leu Leu Ser Asp Asp Met Lys Ala Leu Cys Pro
                 350                 355                 360

 Thr Ile Phe Pro Val Val Pro Arg Leu Leu Asn Arg Met Tyr Asp
                 365                 370                 375

 Lys Ile Phe Ser Gln Ala Asn Thr Pro Leu Lys Arg Trp Leu Leu
                 380                 385                 390

 Glu Phe Ala Ala Lys Arg Lys Gln Ala Glu Val Arg Ser Gly Ile
                 395                 400                 405

 Ile Arg Asn Asp Ser Ile Trp Asp Glu Leu Phe Phe Asn Lys Ile
                 410                 415                 420

 Gln Ala Ser Leu Gly Gly Cys Val Arg Met Ile Val Thr Gly Ala
                 425                 430                 435

 Ala Pro Ala Ser Pro Thr Val Leu Gly Phe Leu Arg Ala Ala Leu
                 440                 445                 450

 Gly Cys Gln Val Tyr Glu Gly Tyr Gly Gln Thr Glu Cys Thr Ala
                 455                 460                 465

 Gly Cys Thr Phe Thr Thr Pro Gly Asp Trp Thr Ser Gly His Val
                 470                 475                 480

 Gly Ala Pro Leu Pro Cys Asn His Ile Lys Leu Val Asp Val Glu
                 485                 490                 495

 Glu Leu Asn Tyr Trp Ala Cys Lys Gly Glu Gly Glu Ile Cys Val
                 500                 505                 510

 Arg Gly Pro Asn Val Phe Lys Gly Tyr Leu Lys Asp Pro Asp Arg
                 515                 520                 525

 Thr Lys Glu Ala Leu Asp Ser Asp Gly Trp Leu His Thr Gly Asp
                 530                 535                 540

 Ile Gly Lys Trp Leu Pro Ala Gly Thr Leu Lys Ile Ile Asp Arg
                 545                 550                 555

 Lys Lys His Ile Phe Lys Leu Ala Gln Gly Glu Tyr Val Ala Pro
                 560                 565                 570

 Glu Lys Ile Glu Asn Ile Tyr Ile Arg Ser Gln Pro Val Ala Gln
                 575                 580                 585

 Ile Tyr Val His Gly Asp Ser Leu Lys Ala Phe Leu Val Gly Ile
                 590                 595                 600

 Val Val Pro Asp Pro Glu Val Met Pro Ser Trp Ala Gln Lys Arg
                 605                 610                 615

 Gly Ile Glu Gly Thr Tyr Ala Asp Leu Cys Thr Asn Lys Asp Leu
                 620                 625                 630

 Lys Lys Ala Ile Leu Glu Asp Met Val Arg Leu Gly Lys Glu Ser
                 635                 640                 645

 Gly Leu His Ser Phe Glu Gln Val Lys Ala Ile His Ile His Ser
                 650                 655                 660

 Asp Met Phe Ser Val Gln Asn Gly Leu Leu Thr Pro Thr Leu Lys
                 665                 670                 675

 Ala Lys Arg Pro Glu Leu Arg Glu Tyr Phe Lys Lys Gln Ile Glu
                 680                 685                 690

 Glu Leu Tyr Ser Ile Pro Met
                 695

<210> 2359
<211> 2530
<212> DNA
<213> Homo sapien

<400> 2359
 aaatccttct tccaatgttc ctcccctctc tgtatgaacc ctgtgttggg 50

 gggcagaaga tggaagccct tggcaagctc gatcgaacca agctactaaa 100

 ttgctgagct cgttttaact gaagtgtgag aaggaggttt aaggcaagta 150

 gacaacatcc tgttgttggg gtgcttctct cttttttgca catctggctg 200

 aactgggagt caggtggttg acttgtgcct ggctgcagta gcagcggcat 250

 ctcccttgca cagttctcct cctcggcctg cccaagagtc caccaggcca 300

 tggacgcagt ggctgtgtat catggcaaaa tcagcaggga aaccggcgag 350

 aagctcctgc ttgccactgg gctggatggc agctatttgc tgagggacag 400

 cgagagcgtg ccaggcgtgt actgcctatg tgtgctgtat cacggttaca 450

 tttatacata ccgagtgtcc cagacagaaa caggttcttg gagtgctgag 500

 acagcacctg gggtacataa aagatatttc cggaaaataa aaaatctcat 550

 ttcagcattt cagaagccag atcaaggcat tgtaatacct ctgcagtatc 600

 cagttgagaa gaagtcctca gctagaagta cacaaggtac tacagggata 650

 agagaagatc ctgatgtctg cctgaaagcc ccatgaagaa aaataaaaca 700

 ccttgtactt tattttctat aatttaaata tatgctaagt cttatatatt 750

 gtagataata cagttcggtg agctacaaat gcatttctaa agccattgta 800

 gtcctgtaat ggaagcatct agcatgtcgt caaagctgaa atggactttt 850

 gtacatagtg aggagctttg aaacgaggat tgggaaaaag taattccgta 900

 ggttattttc agttattata tttacaaatg ggaaacaaaa ggataatgaa 950

 tactttataa aggattaatg tcaattcttg ccaaatataa ataaaaataa 1000

 tcctcagttt ttgtgaaaag ctccattttt agtgaaatat tattttatag 1050

 ctactaattt taaaatgtct tgcttgattg tatggtggga agttggctgg 1100

 tgtcccttgt ctttgccaag ttctccacta gctatggtgt cataggctct 1150

 tttgggattt ttgaagctgt atactgtgtg ctaaaacaag cactaaacaa 1200

 agagtgaagg atttatgttt aattctgaaa gcaaccttct tgcctagtgt 1250

 tctgatattg gacagtaaaa tccacagacc aacctggagt tgaaaatctt 1300

 ataatttaaa atatgctcta aacatgttta tcgtatttga tgctacagga 1350

 tttgaaattg tattacaaat ccaatgaaat gagtttttct tttcatttac 1400

 ctctgcccca gttgtttcta ctacatggaa gacctcattt tgaagggaaa 1450

 tttcagcagc tgcagctcat gagtaactga tttgtaacaa gcctcctttt 1500

 aaagtaaccc tacaaaacca ctggaaagtt tatggttgta ttatttttta 1550

 aaaaaattcc aagtgattga aacctacacg agatacagaa ttttatgcgg 1600

 cattttcttc tcacatttat atttttgtga ttttgtgatt gattatatgt 1650

 cactttgcta cagggctcac agaattcatt cactcaacaa acataatagg 1700

 gcgctgaggg catagaagta aaaacacctg gtccctgctc tcagttcact 1750

 gtcttgttgg acgagaaaag aaacaataac gataaaagac agtgaaagaa 1800

 aataacgata aaagacagtg aaagaaaata acaataaaag acaaggaaaa 1850

 aataacaatg aaagttgata agtacatgat aagcgaggtt ccccgtgtgt 1900

 aggtagatct ggtctttaga ggcagataga taggtcagtg caaatactct 1950

 ggtccatggg ccatatgaaa aggctaagct tcactgtaaa ataataactg 2000

 ggaattctgg attgtgtatg ggtgttggtg aacttggttt taattagtga 2050

 actgctgaga gacagagcta ttctccatgt actggcaaga cctgatttct 2100

 gagcatttaa tatggatgcc gtgggagtac aaaagtggag tgtggcctga 2150

 gtaatgcatt atgggtggtt taccatttct tgaggtaaaa gcatcacatg 2200

 aacttgtaaa ggaatttaaa aatcctactt tcataataag ttgcataggt 2250

 ttaataattt ttaattatat ggcttgagtt taaattgtaa taggcgtaac 2300

 taattttaac tctataatgt gttcattctg gaataatcct aaacatatga 2350

 attatgtttg catgttcact tccaagagcc tttttttgaa aaaaagcttt 2400

 ttttgaatca tcaagtcttt cacatttaaa taaagtgttt gaaagcttta 2450

 tttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2500

 aaaaaaaaaa aaaaaaaaaa aagaaaaaaa 2530

<210> 2360
<211> 128
<212> PRT
<213> Homo sapien

<400> 2360
 Met Asp Ala Val Ala Val Tyr His Gly Lys Ile Ser Arg Glu Thr
   1               5                  10                  15

 Gly Glu Lys Leu Leu Leu Ala Thr Gly Leu Asp Gly Ser Tyr Leu
                  20                  25                  30

 Leu Arg Asp Ser Glu Ser Val Pro Gly Val Tyr Cys Leu Cys Val
                  35                  40                  45

 Leu Tyr His Gly Tyr Ile Tyr Thr Tyr Arg Val Ser Gln Thr Glu
                  50                  55                  60

 Thr Gly Ser Trp Ser Ala Glu Thr Ala Pro Gly Val His Lys Arg
                  65                  70                  75

 Tyr Phe Arg Lys Ile Lys Asn Leu Ile Ser Ala Phe Gln Lys Pro
                  80                  85                  90

 Asp Gln Gly Ile Val Ile Pro Leu Gln Tyr Pro Val Glu Lys Lys
                  95                 100                 105

 Ser Ser Ala Arg Ser Thr Gln Gly Thr Thr Gly Ile Arg Glu Asp
                 110                 115                 120

 Pro Asp Val Cys Leu Lys Ala Pro
                 125

<210> 2361
<211> 483
<212> DNA
<213> Homo sapien

<400> 2361
 ggcatctccc ttgcacagtt ctcctcctcg gcctgcccaa gagtccacca 50

 ggccatggac gcagtggctg tgtatcatgg caaaatcagc agggaaaccg 100

 gcgagaagct cctgcttgcc actgggctgg atggcagcta tttgctgagg 150

 gacagcgaga gcgtgccagg cgtgtactgc ctatgtgtgc tgtatcacgg 200

 ttacatttat acataccgag tgtcccagac agaaacaggt tcttggagtg 250

 ctgagcattt cagaagccag atcaaggcat tgtaatacct ctgcagtatc 300

 cagttgagaa gaagtcctca gctagaagta cacaaggtac tacagggata 350

 agagaagatc ctgatgtctg cctgaaagcc ccatgaagaa aaataaaaca 400

 ccttgtactt tattttctat aatttaaata tatgctaagt cttatatatt 450

 gtagataata cagttcggtg agctacaaat gca 483

<210> 2362
<211> 76
<212> PRT
<213> Homo sapien

<400> 2362
 Met Asp Ala Val Ala Val Tyr His Gly Lys Ile Ser Arg Glu Thr
   1               5                  10                  15

 Gly Glu Lys Leu Leu Leu Ala Thr Gly Leu Asp Gly Ser Tyr Leu
                  20                  25                  30

 Leu Arg Asp Ser Glu Ser Val Pro Gly Val Tyr Cys Leu Cys Val
                  35                  40                  45

 Leu Tyr His Gly Tyr Ile Tyr Thr Tyr Arg Val Ser Gln Thr Glu
                  50                  55                  60

 Thr Gly Ser Trp Ser Ala Glu His Phe Arg Ser Gln Ile Lys Ala
                  65                  70                  75

 Leu


<210> 2363
<211> 461
<212> DNA
<213> Homo sapien

<400> 2363
 ggcatctccc ttgcacagtt ctcctcctcg gcctgcccaa gagtccacca 50

 ggccatggac gcagtggctg tgtatcatgg caaaatcagc agggaaaccg 100

 gcgagaagct cctgcttgcc actgggctgg atggcagcta tttgctgagg 150

 gacagcgaga gcgtgccagg tatcacggtt acatttatac ataccgagtg 200

 tcccagacag aaacaggttc ttggagtgct gagcatttca gaagccagat 250

 caaggcattg taatacctct gcagtatcca gttgagaaga agtcctcagc 300

 tagaagtaca caaggtacta cagggataag agaagatcct gatgtctgcc 350

 tgaaagcccc atgaagaaaa ataaaacacc ttgtacttta ttttctataa 400

 tttaaatata tgctaagtct tatatattgt agataataca gttcggtgag 450

 ctacaaatgc a 461

<210> 2364
<211> 76
<212> PRT
<213> Homo sapien

<400> 2364
 Met Asp Ala Val Ala Val Tyr His Gly Lys Ile Ser Arg Glu Thr
   1               5                  10                  15

 Gly Glu Lys Leu Leu Leu Ala Thr Gly Leu Asp Gly Ser Tyr Leu
                  20                  25                  30

 Leu Arg Asp Ser Glu Ser Val Pro Gly Ile Thr Val Thr Phe Ile
                  35                  40                  45

 His Thr Glu Cys Pro Arg Gln Lys Gln Val Leu Gly Val Leu Ser
                  50                  55                  60

 Ile Ser Glu Ala Arg Ser Arg His Cys Asn Thr Ser Ala Val Ser
                  65                  70                  75

 Ser


<210> 2365
<211> 2564
<212> DNA
<213> Homo sapien

<400> 2365
 ggggcggtcg cagctgaagc aggcctaccc tctgaagagg tccaagcaac 50

 ggaagtacta ctacgaagct gcctttctgg ccatccttga gaaaaataga 100

 cagatggcca aggagagggg cctaataagc cccagtgatt ttgcccagct 150

 gcaaaaatac atggaatact ccaccaaaaa ggtcagtgat gtcctaaagc 200

 tcttcgagga tggcgagatg gctaaatatg tccaaggaga tgccattggg 250

 tacgagggat tccagcaatt cctgaaaatc tatctcgaag tggataatgt 300

 tcccagacac ctaagcctgg cactgtttca atcctttgag actggtcact 350

 gcttaaatga gacaaatgtg acaaaagatg tggtgtgtct caatgatgtt 400

 tcctgctact tttcccttct ggagggtggt cggccagaag acaagttaga 450

 attcaccttc aagctgtacg acacggacag aaatgggatc ctggacagct 500

 cagaagtgga caaaattatc ctacagatga tgcgagtggc tgaatacctg 550

 gattgggatg tgtctgagct gaggccgatt cttcaggaga tgatgaaaga 600

 gattgactat gatggcagtg gctctgtctc tcaagctgag tgggtccggg 650

 ctggggccac caccgtgcca ctgctagtgc tgctgggtct ggagatgact 700

 ctgaaggacg acggacagca catgtggagg cccaagaggt tccccagacc 750

 agtctactgc aatctgtgcg agtcaagcat tggtcttggc aaacagggac 800

 tgagctgtaa cctctgtaag tacactgttc acgaccagtg tgccatgaaa 850

 gccctgcctt gtgaagtcag cacctatgcc aagtctcgga aggacattgg 900

 tgtccaatca catgtgtggg tgcgaggagg ctgtgagtcc gggcgctgcg 950

 accgctgtca gaaaaagatc cggatctacc acagtctgac cgggctgcat 1000

 tgtgtatggt gccacctaga gatccacgat gactgcctgc aagcggtggg 1050

 ccatgagtgt gactgtgggc tgctccggga tcacatcctg cctccatctt 1100

 ccatctatcc cagtgtcctg gcctctggac cggatcgtaa aaatagcaaa 1150

 acaagccaga agaccatgga tgatttaaat ttgagcacct ctgaggctct 1200

 gcggattgac cctgttccta acacccaccc acttctcgtc tttgtcaatc 1250

 ctaagagtgg cgggaagcag gggcagaggg tgctctggaa gttccagtat 1300

 atattaaacc ctcgacaggt gttcaacctc ctaaaggatg gtcctgagat 1350

 agggctccga ttattcaagg atgttcctga tagccggatt ttggtgtgtg 1400

 gtggagacgg cacagtaggc tggattctag agaccattga caaagctaac 1450

 ttgccagttt tgcctcctgt tgctgtgttg cccctgggta ctggaaatga 1500

 tctggctcga tgcctaagat ggggaggagg ttatgaagga cagaatctgg 1550

 caaagatcct caaggattta gagatgagta aagtggtaca tatggatcga 1600

 tggtctgtgg aggtgatacc tcaacaaact gaagaaaaaa gtgacccagt 1650

 cccctttcaa atcatcaata actacttctc tattggcgtg gatgcctcta 1700

 ttgctcatcg attccacatc atgcgagaga aatatccgga gaagttcaac 1750

 agcagaatga agaacaagct atggtacttc gaatttgcca catctgaatc 1800

 catcttctca acatgcaaaa agctggagga gtctttgaca gttgagatct 1850

 gtgggaaacc gctggatctg agcaacctgt ccctagaagg catcgcagtg 1900

 ctaaacatcc ctagcatgca tggtggctcc aacctctggg gtgataccag 1950

 gagaccccat ggggatatct atgggatcaa ccaggcctta ggtgctacag 2000

 ctaaagtcat caccgaccct gatatcctga aaacctgtgt accagaccta 2050

 agtgacaaga gactggaagt ggttgggctg gagggtgcaa ttgagatggg 2100

 ccaaatctat accaagctca agaatgctgg acgtcggctg gccaagtgct 2150

 ctgagatcac cttccacacc acaaaaaccc ttcccatgca aattgacgta 2200

 gaaccctgga tgcagacgcc ctgtacaatc aagatcaccc acaagaacca 2250

 gatgcccatg ctcatgggcc cacccccccg ctccaccaat ttctttggct 2300

 tcttgagcta agggggacac ccttggcctc caagccagcc ttgaacccac 2350

 ctccctgtcc ctggactcta ctcccgaggc tctgtacatt gctgccacat 2400

 actcctgcca gcttggggga gtgttccttc accctcacag tatttattat 2450

 cctgcaccac ctcactgttc cccatgcgca cacacataca cacaccccaa 2500

 aacacataca ttgaaagtgc ctcatctgaa taaaatgact tgtgtttccc 2550

 tttgggatct gctg 2564

<210> 2366
<211> 735
<212> PRT
<213> Homo sapien

<400> 2366
 Met Ala Lys Glu Arg Gly Leu Ile Ser Pro Ser Asp Phe Ala Gln
   1               5                  10                  15

 Leu Gln Lys Tyr Met Glu Tyr Ser Thr Lys Lys Val Ser Asp Val
                  20                  25                  30

 Leu Lys Leu Phe Glu Asp Gly Glu Met Ala Lys Tyr Val Gln Gly
                  35                  40                  45

 Asp Ala Ile Gly Tyr Glu Gly Phe Gln Gln Phe Leu Lys Ile Tyr
                  50                  55                  60

 Leu Glu Val Asp Asn Val Pro Arg His Leu Ser Leu Ala Leu Phe
                  65                  70                  75

 Gln Ser Phe Glu Thr Gly His Cys Leu Asn Glu Thr Asn Val Thr
                  80                  85                  90

 Lys Asp Val Val Cys Leu Asn Asp Val Ser Cys Tyr Phe Ser Leu
                  95                 100                 105

 Leu Glu Gly Gly Arg Pro Glu Asp Lys Leu Glu Phe Thr Phe Lys
                 110                 115                 120

 Leu Tyr Asp Thr Asp Arg Asn Gly Ile Leu Asp Ser Ser Glu Val
                 125                 130                 135

 Asp Lys Ile Ile Leu Gln Met Met Arg Val Ala Glu Tyr Leu Asp
                 140                 145                 150

 Trp Asp Val Ser Glu Leu Arg Pro Ile Leu Gln Glu Met Met Lys
                 155                 160                 165

 Glu Ile Asp Tyr Asp Gly Ser Gly Ser Val Ser Gln Ala Glu Trp
                 170                 175                 180

 Val Arg Ala Gly Ala Thr Thr Val Pro Leu Leu Val Leu Leu Gly
                 185                 190                 195

 Leu Glu Met Thr Leu Lys Asp Asp Gly Gln His Met Trp Arg Pro
                 200                 205                 210

 Lys Arg Phe Pro Arg Pro Val Tyr Cys Asn Leu Cys Glu Ser Ser
                 215                 220                 225

 Ile Gly Leu Gly Lys Gln Gly Leu Ser Cys Asn Leu Cys Lys Tyr
                 230                 235                 240

 Thr Val His Asp Gln Cys Ala Met Lys Ala Leu Pro Cys Glu Val
                 245                 250                 255

 Ser Thr Tyr Ala Lys Ser Arg Lys Asp Ile Gly Val Gln Ser His
                 260                 265                 270

 Val Trp Val Arg Gly Gly Cys Glu Ser Gly Arg Cys Asp Arg Cys
                 275                 280                 285

 Gln Lys Lys Ile Arg Ile Tyr His Ser Leu Thr Gly Leu His Cys
                 290                 295                 300

 Val Trp Cys His Leu Glu Ile His Asp Asp Cys Leu Gln Ala Val
                 305                 310                 315

 Gly His Glu Cys Asp Cys Gly Leu Leu Arg Asp His Ile Leu Pro
                 320                 325                 330

 Pro Ser Ser Ile Tyr Pro Ser Val Leu Ala Ser Gly Pro Asp Arg
                 335                 340                 345

 Lys Asn Ser Lys Thr Ser Gln Lys Thr Met Asp Asp Leu Asn Leu
                 350                 355                 360

 Ser Thr Ser Glu Ala Leu Arg Ile Asp Pro Val Pro Asn Thr His
                 365                 370                 375

 Pro Leu Leu Val Phe Val Asn Pro Lys Ser Gly Gly Lys Gln Gly
                 380                 385                 390

 Gln Arg Val Leu Trp Lys Phe Gln Tyr Ile Leu Asn Pro Arg Gln
                 395                 400                 405

 Val Phe Asn Leu Leu Lys Asp Gly Pro Glu Ile Gly Leu Arg Leu
                 410                 415                 420

 Phe Lys Asp Val Pro Asp Ser Arg Ile Leu Val Cys Gly Gly Asp
                 425                 430                 435

 Gly Thr Val Gly Trp Ile Leu Glu Thr Ile Asp Lys Ala Asn Leu
                 440                 445                 450

 Pro Val Leu Pro Pro Val Ala Val Leu Pro Leu Gly Thr Gly Asn
                 455                 460                 465

 Asp Leu Ala Arg Cys Leu Arg Trp Gly Gly Gly Tyr Glu Gly Gln
                 470                 475                 480

 Asn Leu Ala Lys Ile Leu Lys Asp Leu Glu Met Ser Lys Val Val
                 485                 490                 495

 His Met Asp Arg Trp Ser Val Glu Val Ile Pro Gln Gln Thr Glu
                 500                 505                 510

 Glu Lys Ser Asp Pro Val Pro Phe Gln Ile Ile Asn Asn Tyr Phe
                 515                 520                 525

 Ser Ile Gly Val Asp Ala Ser Ile Ala His Arg Phe His Ile Met
                 530                 535                 540

 Arg Glu Lys Tyr Pro Glu Lys Phe Asn Ser Arg Met Lys Asn Lys
                 545                 550                 555

 Leu Trp Tyr Phe Glu Phe Ala Thr Ser Glu Ser Ile Phe Ser Thr
                 560                 565                 570

 Cys Lys Lys Leu Glu Glu Ser Leu Thr Val Glu Ile Cys Gly Lys
                 575                 580                 585

 Pro Leu Asp Leu Ser Asn Leu Ser Leu Glu Gly Ile Ala Val Leu
                 590                 595                 600

 Asn Ile Pro Ser Met His Gly Gly Ser Asn Leu Trp Gly Asp Thr
                 605                 610                 615

 Arg Arg Pro His Gly Asp Ile Tyr Gly Ile Asn Gln Ala Leu Gly
                 620                 625                 630

 Ala Thr Ala Lys Val Ile Thr Asp Pro Asp Ile Leu Lys Thr Cys
                 635                 640                 645

 Val Pro Asp Leu Ser Asp Lys Arg Leu Glu Val Val Gly Leu Glu
                 650                 655                 660

 Gly Ala Ile Glu Met Gly Gln Ile Tyr Thr Lys Leu Lys Asn Ala
                 665                 670                 675

 Gly Arg Arg Leu Ala Lys Cys Ser Glu Ile Thr Phe His Thr Thr
                 680                 685                 690

 Lys Thr Leu Pro Met Gln Ile Asp Val Glu Pro Trp Met Gln Thr
                 695                 700                 705

 Pro Cys Thr Ile Lys Ile Thr His Lys Asn Gln Met Pro Met Leu
                 710                 715                 720

 Met Gly Pro Pro Pro Arg Ser Thr Asn Phe Phe Gly Phe Leu Ser
                 725                 730                 735

<210> 2367
<211> 1807
<212> DNA
<213> Homo sapien

<400> 2367
 ctctgagtca ccaacctgag gctgccccgg ccgcctgcgc acccggcagc 50

 accatgacag atcaggcctt tgtgacacta accacaaacg atgcctacgc 100

 caaaggtgcc ctggtcctgg gatcatctct gaaacagcac aggaccacca 150

 ggaggctggt cgtgctcgcc acccctcagg tctcagactc catgagaaaa 200

 gttttagaga cagtctttga tgaagtcatc atggtagatg tcttggacag 250

 tggcgattct gctcatctaa ccttaatgaa gaggccagag ttgggtgtca 300

 cgctgacaaa gctccactgc tggtcgctta cacagtattc aaaatgtgta 350

 ttcatggatg cagatactct ggtcctagca aatattgatg atctttttga 400

 cagagaagaa ttgtcagcag caccagaccc agggtggcct gactgcttca 450

 attccggagt cttcgtttat cagccttcag ttgaaacata caatcagctg 500

 ttgcatcttg cttctgagca aggtagtttt gatggtgggg accaaggcat 550

 actgaacaca ttttttagca gctgggcaac aacagatatc agaaaacacc 600

 tgccgtttat ttataaccta agcagcatct ctatatactc ctacctcccg 650

 gcatttaaag tgtttggtgc aagtgccaaa gttgtgcatt tcctgggacg 700

 agtcaaacca tggaattata cttatgatcc caaaacaaaa agtgtcaaaa 750

 gtgaggccca tgatcccaac atgactcatc cagagtttct catcctgtgg 800

 tggaacatct ttaccaccaa cgttttacct ctgcttcaac aatttggcct 850

 tgtcaaagac acctgctcat atgtaaatgt gctttcagac ttggtctata 900

 cactggcttt ctcttgtggc ttctgtagaa aggaagatgt ctcaggagcc 950

 atatcacatc tgtcccttgg ggagatccca gctatggcac agccgtttgt 1000

 atcctcggaa gaacggaagg aacgatggga acagggccag gctgattata 1050

 tgggagcaga ttcctttgac aacatcaaga ggaaacttga cacttacctc 1100

 cagtagaaac actgcatttt tctgtgaaca catccacttc acaagccttg 1150

 tttctgatac ttagtatcta gagctgggtt gagaaaagtc tgttacagtt 1200

 gctagaggtt ttcattaaaa cttatcagat gagaggcttt tttaggataa 1250

 gaggtgagaa ctgggcaaaa gttgtgaagc agcaattctg ttatatggac 1300

 agtgttctgc tttttaatcc tatttagctt gtttcagaaa ttctcacttt 1350

 tgttgactgc caacatacaa agtaagggaa actcaagata ttaagatggc 1400

 tgtatcagtt cttaaaatct gcagagcctg gttcaaaatc agtcactccc 1450

 ttcagaagca gacatggcat ctgttccttg cttgcttgtt ggttgtgtac 1500

 ctttcacgag acctgaattt tagaattgcc cagtgctgcc agagtgagtg 1550

 agtgtaattc tcctttcagg taaagatagg ctatctcaac actgctgagt 1600

 gattcataaa catatcaacc aatagcatta acccatttta tttcctgtcc 1650

 ttagtgtctg aagatgctca ccagttttct gtgtacagta aggcagcatg 1700

 ctaaaatgct tttgttcagt tctggatatt tgaaaatagc agtgtgttct 1750

 ctgatggtta cctgcagtgg caccctgtac aaaaaataaa agacttattg 1800

 gtgtaaa 1807

<210> 2368
<211> 350
<212> PRT
<213> Homo sapien

<400> 2368
 Met Thr Asp Gln Ala Phe Val Thr Leu Thr Thr Asn Asp Ala Tyr
   1               5                  10                  15

 Ala Lys Gly Ala Leu Val Leu Gly Ser Ser Leu Lys Gln His Arg
                  20                  25                  30

 Thr Thr Arg Arg Leu Val Val Leu Ala Thr Pro Gln Val Ser Asp
                  35                  40                  45

 Ser Met Arg Lys Val Leu Glu Thr Val Phe Asp Glu Val Ile Met
                  50                  55                  60

 Val Asp Val Leu Asp Ser Gly Asp Ser Ala His Leu Thr Leu Met
                  65                  70                  75

 Lys Arg Pro Glu Leu Gly Val Thr Leu Thr Lys Leu His Cys Trp
                  80                  85                  90

 Ser Leu Thr Gln Tyr Ser Lys Cys Val Phe Met Asp Ala Asp Thr
                  95                 100                 105

 Leu Val Leu Ala Asn Ile Asp Asp Leu Phe Asp Arg Glu Glu Leu
                 110                 115                 120

 Ser Ala Ala Pro Asp Pro Gly Trp Pro Asp Cys Phe Asn Ser Gly
                 125                 130                 135

 Val Phe Val Tyr Gln Pro Ser Val Glu Thr Tyr Asn Gln Leu Leu
                 140                 145                 150

 His Leu Ala Ser Glu Gln Gly Ser Phe Asp Gly Gly Asp Gln Gly
                 155                 160                 165

 Ile Leu Asn Thr Phe Phe Ser Ser Trp Ala Thr Thr Asp Ile Arg
                 170                 175                 180

 Lys His Leu Pro Phe Ile Tyr Asn Leu Ser Ser Ile Ser Ile Tyr
                 185                 190                 195

 Ser Tyr Leu Pro Ala Phe Lys Val Phe Gly Ala Ser Ala Lys Val
                 200                 205                 210

 Val His Phe Leu Gly Arg Val Lys Pro Trp Asn Tyr Thr Tyr Asp
                 215                 220                 225

 Pro Lys Thr Lys Ser Val Lys Ser Glu Ala His Asp Pro Asn Met
                 230                 235                 240

 Thr His Pro Glu Phe Leu Ile Leu Trp Trp Asn Ile Phe Thr Thr
                 245                 250                 255

 Asn Val Leu Pro Leu Leu Gln Gln Phe Gly Leu Val Lys Asp Thr
                 260                 265                 270

 Cys Ser Tyr Val Asn Val Leu Ser Asp Leu Val Tyr Thr Leu Ala
                 275                 280                 285

 Phe Ser Cys Gly Phe Cys Arg Lys Glu Asp Val Ser Gly Ala Ile
                 290                 295                 300

 Ser His Leu Ser Leu Gly Glu Ile Pro Ala Met Ala Gln Pro Phe
                 305                 310                 315

 Val Ser Ser Glu Glu Arg Lys Glu Arg Trp Glu Gln Gly Gln Ala
                 320                 325                 330

 Asp Tyr Met Gly Ala Asp Ser Phe Asp Asn Ile Lys Arg Lys Leu
                 335                 340                 345

 Asp Thr Tyr Leu Gln
                 350

<210> 2369
<211> 4068
<212> DNA
<213> Homo sapien

<400> 2369
 gaattcctcc tctcttcacc ccgttagctg ttttcaatgt aatgctgccg 50

 tccttctctt gcactgcctt ctgcgctaac acctccattc ctgtttataa 100

 ccgtgtattt attacttaat gtatataatg taatgttttg taagttatta 150

 atttatatat ctaacattgc ctgccaatgg tggtgttaaa tttgtgtaga 200

 aaactctgcc taagagttac gactttttct tgtaatgttt tgtattgtgt 250

 attatataac ccaaacgtca cttagtagag acatatggcc cccttggcag 300

 agaggacagg ggtgggcttt tgttcaaagg gtctgccctt tccctgcctg 350

 agttgctact tctgcacaac ccctttatga accagttttc acccgaattt 400

 tgactgtttc atttagaaga aaagcaaaat gagaaaaagc tttcctcatt 450

 tctccttgag atggcaaagc actcagaaat gacatcacat accctaaaga 500

 accctgggat gactaaggca gagagagtct gagaaaactc tttggtgctt 550

 ctgcctttag ttttaggaca catttatgca gatgagctta taagagaccg 600

 ttccctccgc cttcttcctc agaggaagtt tcttggtaga tcaccgacac 650

 ctcatccagg cggggggttg gggggaaact tggcaccagc catcccaggc 700

 agagcaccac tgtgatttgt tctcctggtg gagagagctg gaaggaagga 750

 gccagcgtgc aaataatgaa ggagcacggg ggcaccttca gtagcaccgg 800

 aatcagcggt ggtagcggtg actctgctat ggacagcctg cagccgctcc 850

 agcctaacta catgcctgtg tgtttgtttg cagaagaatc ttatcaaaaa 900

 ttagcaatgg aaacgctgga ggaattagac tggtgtttag accagctaga 950

 gaccatacag acctaccggt ctgtcagtga gatggcttct aacaagttca 1000

 aaagaatgct gaaccgggag ctgacacacc tctcagagat gagccgatca 1050

 gggaaccagg tgtctgaata catttcaaat actttcttag acaagcagaa 1100

 tgatgtggag atcccatctc ctacccagaa agacagggag aaaaagaaaa 1150

 agcagcagct catgacccag ataagtggag tgaagaaatt aatgcatagt 1200

 tcaagcctaa acaatacaag catctcacgc tttggagtca acactgaaaa 1250

 tgaagatcac ctggccaagg agctggaaga cctgaacaaa tggggtctta 1300

 acatctttaa tgtggctgga tattctcaca atagacccct aacatgcatc 1350

 atgtatgcta tattccagga aagagacctc ctaaagacat tcagaatctc 1400

 atctgacaca tttataacct acatgatgac tttagaagac cattaccatt 1450

 ctgacgtggc atatcacaac agcctgcacg ctgctgatgt agcccagtcg 1500

 acccatgttc tcctttctac accagcatta gacgctgtct tcacagattt 1550

 ggagatcctg gctgccattt ttgcagctgc catccatgac gttgatcatc 1600

 ctggagtctc caatcagttt ctcatcaaca caaattcaga acttgctttg 1650

 atgtataatg atgaatctgt gttggaaaat catcaccttg ctgtgggttt 1700

 caaactgctg caagaagaac actgtgacat cttcatgaat ctcaccaaga 1750

 agcagcgtca gacactcagg aagatggtta ttgacatggt gttagcaact 1800

 gatatgtcta aacatatgag cctgctggca gacctgaaga caatggtaga 1850

 aacgaagaaa gttacaagtt caggcgttct tctcctagac aactataccg 1900

 atcgcattca ggtccttcgc aacatggtac actgtgcaga cctgagcaac 1950

 cccaccaagt ccttggaatt gtatcggcaa tggacagacc gcatcatgga 2000

 ggaatttttc cagcagggag acaaagagcg ggagagggga atggaaatta 2050

 gcccaatgtg tgataaacac acagcttctg tggaaaaatc ccaggttggt 2100

 ttcatcgact acattgtcca tccattgtgg gagacatggg cagatttggt 2150

 acagcctgat gctcaggaca ttctcgatac cttagaagat aacaggaact 2200

 ggtatcagag catgatacct caaagtccct caccaccact ggacgagcag 2250

 aacagggact gccagggtct gatggagaag tttcagtttg aactgactct 2300

 cgatgaggaa gattctgaag gacctgagaa ggagggagag ggacacagct 2350

 atttcagcag cacaaagacg ctttgtgtga ttgatccaga aaacagagat 2400

 tccctgggag agactgacat agacattgca acagaagaca agtcccccgt 2450

 ggatacataa tccccctctc cctgtggaga tgaacattct atccttgatg 2500

 agcatgccag ctatgtggta gggccagccc accatggggg ccaagacctg 2550

 cacaggacaa gggccacctg gcctttcagt tacttgagtt tggagtcaga 2600

 aagcaagacc aggaagcaaa tagcagctca ggaaatccca cggttgactt 2650

 gccttgatgg caagcttggt ggagagggct gaagctgttg ctgggggccg 2700

 attctgatca agacacatgg cttgaaaatg gaagacacaa aactgagaga 2750

 tcattctgca ctaagtttcg ggaacttatc cccgacagtg actgaactca 2800

 ctgactaata acttcattta tgaatcttct cacttgtccc tttgtctgcc 2850

 aacctgtgtg ccttttttgt aaaacatttt catgtcttta aaatgcctgt 2900

 tgaatacctg gagtttagta tcaacttcta cacagataag ctttcaaagt 2950

 tgacaaactt ttttgactct ttctggaaaa gggaaagaaa atagtcttcc 3000

 ttctttcttg ggcaatatcc ttcactttac tacagttact tttgcaaaca 3050

 gacagaaagg atacacttct aaccacattt tacttccttc ccctgttgtc 3100

 cagtccaact ccacagtcac tcttaaaact tctctctgtt tgcctgcctc 3150

 caacagtact tttaactttt tgctgtaaac agaataaaat tgaacaaatt 3200

 agggggtaga aaggagcagt ggtgtcgttc accgtgagag tctgcataga 3250

 actcagcagt gtgccctgct gtgtcttgga ccctgccccc cacaggagtt 3300

 gctacagtcc ctggccctgc ttcccatcct cctctcttca ccccgttagc 3350

 tgttttcaat gtaatgctgc cgtccttctc ttgcactgcc ttctgcgcta 3400

 acacctccat tcctgtttat aaccgtgtat ttattactta atgtatataa 3450

 tgtaatgttt tgtaagttat taatttatat atctaacatt gcctgccaat 3500

 ggtggtgtta aatttgtgta gaaaactctg cctaagagtt acgacttttt 3550

 cttgtaatgt tttgtattgt gtattatata acccaaacgt cacttagtag 3600

 agacatatgg cccccttggc agagaggaca ggggtgggct tttgttcaaa 3650

 gggtctgccc tttccctgcc tgagttgcta cttctgcaca acccctttat 3700

 gaaccagttt tggaaacaat attctcacat tagatactaa atggtttata 3750

 ctgagtcttt tacttttgta tagcttgata ggggcagggg caatgggatg 3800

 tagtttttac ccaggttcta tccaaatcta tgtgggcatg agttgggtta 3850

 taactggatc ctactatcat tgtggctttg gttcaaaagg aaacactaca 3900

 tttgctcaca gatgattctt ctgattcttc tgaatgctcc cgaactactg 3950

 actttgaaga ggtagcctcc tgcctgccat taagcaggaa tgtcatgttc 4000

 cagttcatta caaaagaaaa caataaaaca atgtgaattt ttataataaa 4050

 aaaaaaaaaa aggaattc 4068

<210> 2370
<211> 564
<212> PRT
<213> Homo sapien

<400> 2370
 Met Lys Glu His Gly Gly Thr Phe Ser Ser Thr Gly Ile Ser Gly
   1               5                  10                  15

 Gly Ser Gly Asp Ser Ala Met Asp Ser Leu Gln Pro Leu Gln Pro
                  20                  25                  30

 Asn Tyr Met Pro Val Cys Leu Phe Ala Glu Glu Ser Tyr Gln Lys
                  35                  40                  45

 Leu Ala Met Glu Thr Leu Glu Glu Leu Asp Trp Cys Leu Asp Gln
                  50                  55                  60

 Leu Glu Thr Ile Gln Thr Tyr Arg Ser Val Ser Glu Met Ala Ser
                  65                  70                  75

 Asn Lys Phe Lys Arg Met Leu Asn Arg Glu Leu Thr His Leu Ser
                  80                  85                  90

 Glu Met Ser Arg Ser Gly Asn Gln Val Ser Glu Tyr Ile Ser Asn
                  95                 100                 105

 Thr Phe Leu Asp Lys Gln Asn Asp Val Glu Ile Pro Ser Pro Thr
                 110                 115                 120

 Gln Lys Asp Arg Glu Lys Lys Lys Lys Gln Gln Leu Met Thr Gln
                 125                 130                 135

 Ile Ser Gly Val Lys Lys Leu Met His Ser Ser Ser Leu Asn Asn
                 140                 145                 150

 Thr Ser Ile Ser Arg Phe Gly Val Asn Thr Glu Asn Glu Asp His
                 155                 160                 165

 Leu Ala Lys Glu Leu Glu Asp Leu Asn Lys Trp Gly Leu Asn Ile
                 170                 175                 180

 Phe Asn Val Ala Gly Tyr Ser His Asn Arg Pro Leu Thr Cys Ile
                 185                 190                 195

 Met Tyr Ala Ile Phe Gln Glu Arg Asp Leu Leu Lys Thr Phe Arg
                 200                 205                 210

 Ile Ser Ser Asp Thr Phe Ile Thr Tyr Met Met Thr Leu Glu Asp
                 215                 220                 225

 His Tyr His Ser Asp Val Ala Tyr His Asn Ser Leu His Ala Ala
                 230                 235                 240

 Asp Val Ala Gln Ser Thr His Val Leu Leu Ser Thr Pro Ala Leu
                 245                 250                 255

 Asp Ala Val Phe Thr Asp Leu Glu Ile Leu Ala Ala Ile Phe Ala
                 260                 265                 270

 Ala Ala Ile His Asp Val Asp His Pro Gly Val Ser Asn Gln Phe
                 275                 280                 285

 Leu Ile Asn Thr Asn Ser Glu Leu Ala Leu Met Tyr Asn Asp Glu
                 290                 295                 300

 Ser Val Leu Glu Asn His His Leu Ala Val Gly Phe Lys Leu Leu
                 305                 310                 315

 Gln Glu Glu His Cys Asp Ile Phe Met Asn Leu Thr Lys Lys Gln
                 320                 325                 330

 Arg Gln Thr Leu Arg Lys Met Val Ile Asp Met Val Leu Ala Thr
                 335                 340                 345

 Asp Met Ser Lys His Met Ser Leu Leu Ala Asp Leu Lys Thr Met
                 350                 355                 360

 Val Glu Thr Lys Lys Val Thr Ser Ser Gly Val Leu Leu Leu Asp
                 365                 370                 375

 Asn Tyr Thr Asp Arg Ile Gln Val Leu Arg Asn Met Val His Cys
                 380                 385                 390

 Ala Asp Leu Ser Asn Pro Thr Lys Ser Leu Glu Leu Tyr Arg Gln
                 395                 400                 405

 Trp Thr Asp Arg Ile Met Glu Glu Phe Phe Gln Gln Gly Asp Lys
                 410                 415                 420

 Glu Arg Glu Arg Gly Met Glu Ile Ser Pro Met Cys Asp Lys His
                 425                 430                 435

 Thr Ala Ser Val Glu Lys Ser Gln Val Gly Phe Ile Asp Tyr Ile
                 440                 445                 450

 Val His Pro Leu Trp Glu Thr Trp Ala Asp Leu Val Gln Pro Asp
                 455                 460                 465

 Ala Gln Asp Ile Leu Asp Thr Leu Glu Asp Asn Arg Asn Trp Tyr
                 470                 475                 480

 Gln Ser Met Ile Pro Gln Ser Pro Ser Pro Pro Leu Asp Glu Gln
                 485                 490                 495

 Asn Arg Asp Cys Gln Gly Leu Met Glu Lys Phe Gln Phe Glu Leu
                 500                 505                 510

 Thr Leu Asp Glu Glu Asp Ser Glu Gly Pro Glu Lys Glu Gly Glu
                 515                 520                 525

 Gly His Ser Tyr Phe Ser Ser Thr Lys Thr Leu Cys Val Ile Asp
                 530                 535                 540

 Pro Glu Asn Arg Asp Ser Leu Gly Glu Thr Asp Ile Asp Ile Ala
                 545                 550                 555

 Thr Glu Asp Lys Ser Pro Val Asp Thr
                 560

<210> 2371
<211> 9517
<212> DNA
<213> Homo sapien

<400> 2371
 gttgctgtcg gagagagaaa gccgcacccg agaggaggtg tgggtgttcc 50

 gcttccatcc taacggaacg agctccctct tcgcggacat gggattaccc 100

 agcggctgct aacccctctc ctcgccctgc tcccccaaac cggcgtggct 150

 ccccgggcac caaggagctg actacagagg agcaggattt gcacccctcg 200

 ctgggcttgc tttggcaaca gagtgcctga cccaggtcag gattttcaag 250

 aaagacatgt ctgacaaaat gtctagcttc ctacatattg gagacatttg 300

 ttctctgtac gcggagggat cgacaaatgg atttattagc accttgggcc 350

 tggttgatga tcgttgtgtt gtacagccag aaaccgggga ccttaacaat 400

 ccacctaaga aattcagaga ctgcctcttt aagctatgtc ccatgaaccg 450

 ctactctgcc caaaagcagt tctggaaagc cgctaagcct ggggccaaca 500

 gcaccacaga cgcagtgcta ctcaacaaac tgcaccacgc tgcagacttg 550

 gaaaagaagc agaatgagac agaaaacagg aaattgctgg ggaccgtaat 600

 ccagtatggc aatgtgatcc agctcctgca tttgaaaagt aataaatacc 650

 taacagtgaa taagaggctt cctgctctgt tggagaagaa tgccatgaga 700

 gtcacattgg acgaggctgg aaatgaaggg tcctggtttt atattcagcc 750

 attctacaag ctgcgatcca ttggagacag cgtggtcata ggtgacaagg 800

 tggttctgaa ccccgtcaat gctggtcagc ccctacatgc tagcagccat 850

 caactggtag ataacccagg ctgcaatgag gtcaattccg tcaactgcaa 900

 tacaagctgg aaaatagtcc ttttcatgaa atggagtgat aacaaagacg 950

 acatattaaa ggggggtgac gtggtgaggc tgtttcatgc tgagcaggag 1000

 aagtttctca cctgtgacga acacaggaag aagcagcacg tcttcctgag 1050

 aaccacgggc cggcagtcgg ccacatctgc caccagttca aaagccctgt 1100

 gggaggtgga ggtggtccag catgacccat gtcggggcgg agcagggtat 1150

 tggaacagcc ttttccgttt caagcatctg gccacggggc attacttggc 1200

 agcagaggtg gaccctgatc aggacgcctc tcgaagtagg ttgcggaatg 1250

 cccaagaaaa gatggtatac tccctggtct ctgtgcctga aggcaatgac 1300

 atctcctcca ttttcgagct agatcccacc actctgcgtg gaggtgacag 1350

 ccttgtccca aggaactctt atgttcggct cagacaccta tgtactaata 1400

 cctgggttca cagcacaaat attcctattg acaaggaaga agaaaagccc 1450

 gtgatgctga aaattggcac ctctcctgtg aaggaggata aggaagcatt 1500

 tgccatagtt ccggtttctc ctgctgaagt tcgggacctg gactttgcca 1550

 atgatgccag caaggtgctg ggctccattg ctgggaagct agagaagggc 1600

 accatcaccc agaatgaaag gaggtctgta accaagctgc tagaagattt 1650

 ggtttacttc gtcactggtg gaactaattc tggtcaagat gttctcgaag 1700

 ttgtcttctc caagcccaac agagaacggc agaaactgat gagagaacag 1750

 aatattctca agcagatctt caagttgtta caagccccat tcacagactg 1800

 cggtgatggc ccaatgcttc ggctggaaga gctcggggac cagcggcacg 1850

 ctcctttcag acacatctgc cggctctgct acagggtgct gagacactcg 1900

 cagcaagact acaggaagaa ccaggagtat atagccaagc agtttggctt 1950

 catgcagaag cagattggct atgatgtgtt ggctgaagac actatcactg 2000

 ccctgctcca caataatcgg aaactcctgg aaaaacacat taccgcggca 2050

 gagattgaca catttgtcag cctggtgcga aagaacaggg agcccagatt 2100

 cttagattac ctctccgacc tctgtgtctc catgaacaaa tcaattccag 2150

 tgacccagga actgatatgt aaagctgtgc tgaaccccac caacgctgac 2200

 atcctgattg agaccaaatt ggttctttct cgttttgaat ttgaaggtgt 2250

 ctcttccact ggagagaatg ctctggaggc aggagaagac gaggaagagg 2300

 tgtggctgtt ttggagggac agcaacaaag agattcgcag caagagtgtg 2350

 agggaattgg ctcaggatgc taaagaaggg cagaaggagg accgagacgt 2400

 tctcagctac tacagatatc agctgaacct ctttgcgagg atgtgtctgg 2450

 accgccaata cctggccatc aacgaaatct caggccagct ggatgtcgat 2500

 ctcattctcc gctgcatgtc tgacgagaac ctgccctatg acctcagggc 2550

 gtccttctgc cgcctcatgc ttcacatgca tgtggaccga gatccccagg 2600

 aacaagtcac ccccgtgaaa tatgcccgcc tctggtcgga gattccctcg 2650

 gagatcgcca ttgacgacta tgatagtagt ggagcttcca aagatgaaat 2700

 taaggagaga tttgctcaga ccatggagtt tgtggaggag tatttaagag 2750

 atgtggtttg tcagaggttc cctttctctg ataaagagaa gaataagctt 2800

 acgtttgagg ttgtaaattt agctaggaat ctcatatact ttggtttcta 2850

 caacttctct gaccttctcc gattaactaa gatccttctg gccatattgg 2900

 actgtgtaca tgtgacaaca atcttcccca ttagcaagat ggcgaaagga 2950

 gaagagaata aaggcagtaa cgtgatgaga tctattcatg gcgtgggaga 3000

 gctgatgacc caggtggtgc tccggggagg aggctttttg cccatgactc 3050

 ccatggctgc tgcccctgaa ggcaatgtga agcaggcaga gcctgagaag 3100

 gaggacatca tggtcatgga caccaagctg aagatcattg agatactcca 3150

 gtttattttg aatgtgaggt tggattatag gatctcctgc ctcctgtgta 3200

 tatttaagcg agagtttgat gaaagcaatt cccagacttc agaaacatcc 3250

 tccggaaaca gcagccaaga agggccaagt aatgtaccag gtgctcttga 3300

 ctttgaacac attgaagaac aagcagaagg catctttgga ggaagtgagg 3350

 agaacacccc actggacttg gatgaccacg gcggcagaac ctttctccgt 3400

 gtcctgctcc acttgacgat gcatgactac ccacccctgg tgtcaggggc 3450

 cctgcagctc ctcttccggc acttcagcca gaggcaggag gtgctccagg 3500

 ccttcaaaca ggttcaactg ctggttacca gccaagatgt ggacaactac 3550

 aaacagatca aacaagactt ggatcaactg aggtccatcg tggaaaagtc 3600

 agagctttgg gtgtacaaag ggcagggccc cgatgagact atggatggtg 3650

 catctggaga aaatgaacat aagaaaacgg aggagggaaa taacaagcca 3700

 caaaagcatg aaagcaccag cagctacaac tacagagtgg tcaaagagat 3750

 tttgattcgg cttagcaaac tctgtgttca agagagtgcc tcagtgagaa 3800

 agagcaggaa gcagcaacag cgtctgctcc ggaacatggg cgcgcacgcc 3850

 gtggtgctgg agctgctgca gattccctat gagaaggccg aagataccaa 3900

 gatgcaagag ataatgaggt tggctcatga atttttgcag aatttctgcg 3950

 caggcaacca gcagaatcaa gctttgctac ataaacacat aaacctgttt 4000

 ctcaacccag ggatcctgga ggcagtaacc atgcagcaca tcttcatgaa 4050

 caatttccag ctttgcagtg agatcaacga gagagttgtt cagcacttcg 4100

 ttcactgcat agagactcac ggtcggaatg tccagtatat aaagttctta 4150

 cagacaattg tcaaggcaga agggaaattt attaaaaaat gccaagacat 4200

 ggttatggcc gagctggtca attcgggaga ggatgtcctc gtgttctaca 4250

 acgacagagc ctctttccag actctgatcc agatgatgcg gtcagaacgg 4300

 gatcggatgg atgagaacag ccctctcatg taccacatcc acttggtcga 4350

 gctcctggct gtgtgcacgg agggtaagaa tgtctacaca gagatcaagt 4400

 gcaactccct gctcccgctg gatgacatcg ttcgcgtggt gacccacgag 4450

 gactgcatcc ctgaggttaa aattgcatac attaacttcc tgaatcactg 4500

 ctatgtggat acagaggtgg aaatgaagga gatttatacc agcaatcaca 4550

 tgtggaaatt gtttgagaat ttccttgtag acatctgcag ggcctgtaac 4600

 aacactagtg acaggaaaca tgcagactcg attttggaga agtatgtcac 4650

 cgaaatcgtc atgagtattg ttactacttt cttcagctct cccttctcag 4700

 accagagtac gactttgcag actcgccagc ctgtctttgt gcaactgctg 4750

 caaggcgtgt tcagggttta ccactgcaac tggttaatgc caagccaaaa 4800

 agcctccgtg gagagctgta ttcgggtgct gtctgatgta gccaagagcc 4850

 gggccattgc cattcccgtg gacctggaca gccaagtcaa caacctcttt 4900

 ctcaagtccc acagcattgt gcagaaaaca gccatgaact ggcggctctc 4950

 agcccgcaat gccgcacgca gggactctgt tctggcagct tccagagact 5000

 accggaatat cattgagaga ttgcaggaca tcgtctccgc gctggaggac 5050

 cgtctcaggc ccctggtgca ggcagagtta tctgtgctcg tggatgttct 5100

 ccacagaccc gagctgcttt tcccagagaa cacagacgcc agaaggaaat 5150

 gtgaaagtgg cggtttcatt tgcaagttaa taaagcatac aaaacagctg 5200

 ctagaagaaa atgaagagaa gctctgcatt aaggtcctac agaccctgag 5250

 ggaaatgatg accaaagata gaggctatgg agaaaagggt gaggcgctca 5300

 ggcaagttct ggtcaaccgt tactatggaa acgtcagacc ttcgggacga 5350

 agagagagcc ttaccagctt tggcaatggc ccactgtcag caggaggacc 5400

 cggcaagccc gggggaggag ggggaggttc cggatccagc tctatgagca 5450

 ggggtgagat gagtctggcc gaggttcagt gtcaccttga caaggagggg 5500

 gcttccaatc tagttatcga cctcatcatg aacgcatcca gtgaccgagt 5550

 gttccatgaa agcattctcc tggccattgc ccttctggaa ggaggcaaca 5600

 ccaccatcca gcactccttt ttctgtcgct tgacagaaga taagaagtca 5650

 gagaaattct ttaaggtgtt ttatgaccgg atgaaggtgg cccagcaaga 5700

 aatcaaagca acagtgacag tgaacaccag tgacttggga aataaaaaga 5750

 aagacgatga ggtagacagg gatgccccat cacggaaaaa agctaaagag 5800

 cccacaacac agataacaga agaggtccgg gatcagctcc tggaggcctc 5850

 cgctgccacc aggaaagcct tcaccacttt caggagggag gctgatcccg 5900

 acgaccacta ccagcctgga gagggcaccc aggccactgc cgacaaggcc 5950

 aaggacgacc tggagatgag cgcggtcatc accatcatgc agcccatcct 6000

 ccgcttcctt cagctcctgt gtgaaaacca caaccgagac ctgcagaact 6050

 tcctccgttg ccaaaataac aagaccaact acaatttggt atgtgagacc 6100

 ctgcagtttc tggactgtat ttgtggaagc acaactggag gccttggtct 6150

 tctgggcttg tatataaatg aaaagaacgt agcgcttatc aaccaaaccc 6200

 tggaaagtct gaccgaatac tgtcaaggac cttgccatga gaaccagaac 6250

 tgcatagcca cccatgaatc caatggcatt gacatcatca cagccctgat 6300

 cctcaatgat atcaatcctt tgggaaagaa gaggatggac cttgtgttag 6350

 aactgaagaa caatgcctcg aagttgctcc tggccatcat ggaaagcagg 6400

 cacgacagtg aaaacgcaga gaggatactt tataacatga ggcccaagga 6450

 actggtggaa gtgatcaaga aagcctacat gcaaggtgaa gtggaatttg 6500

 aggatggaga aaacggtgag gatggggcgg cgtcccccag gaacgtgggg 6550

 cacaacatct acatattagc ccatcagttg gctcggcata acaaagaact 6600

 tcagagcatg ctgaaacctg gtggccaagt ggacggagat gaagccctgg 6650

 agttttatgc caagcacacg gcgcagatag agattgtcag attagaccga 6700

 acaatggaac agatagtctt tcccgtgccc agcatatgtg aattcctaac 6750

 caaggagtca aaactacgaa tttactatac tacagagaga gacgaacaag 6800

 gcagcaaaat caatgatttc tttctgcggt ctgaagacct cttcaatgaa 6850

 atgaattggc agaagaaact gagagcccag cccgtgttgt actggtgtgc 6900

 ccgcaacatg tctttctgga gcagcatttc gtttaacctg gccgtcctga 6950

 tgaacctgct ggtggcgttt ttctacccgt ttaagggagt ccgaggagga 7000

 accctggagc cccactggtc gggactcctg tggacagcca tgctcatctc 7050

 tctggccatc gtcattgccc tccccaagcc ccatggcatc cgggccttaa 7100

 ttgcctccac aattctacga ctgatatttt cagtcgggtt acaacccacg 7150

 ttgtttcttc tgggcgcttt caatgtatgc aataaaatca tctttctaat 7200

 gagctttgtg ggcaactgtg ggacattcac aagaggctac cgagccatgg 7250

 ttctggatgt tgagttcctc tatcatttgt tgtatctggt gatctgtgcc 7300

 atggggctct ttgtccatga attcttctac agtctgctgc tttttgattt 7350

 agtgtacaga gaagagactt tgcttaatgt cattaaaagt gtcactcgca 7400

 atggacggtc catcatcctg acagcagttc tggctctgat cctcgtttac 7450

 ctgttctcaa tagtgggcta tcttttcttc aaggatgact ttatcttgga 7500

 agtagatagg ctgcccaatg aaacagctgt tccagaaacc ggcgagagtt 7550

 tggcaagcga gttcctgttc tccgatgtgt gtagggtgga gagtggggag 7600

 aactgctcct ctcctgcacc cagagaagag ctggtccctg cagaagagac 7650

 ggaacaggat aaagagcaca catgtgagac gctgctgatg tgcattgtca 7700

 ccgtgctgag tcacgggctg cggagcgggg gtggagtagg agatgtactc 7750

 aggaaaccgt ccaaagagga acccctgttt gctgctagag ttatttatga 7800

 cctcttgttc ttcttcatgg tcatcatcat tgttcttaac ctgatttttg 7850

 gggttatcat tgacactttt gctgacctga ggagtgagaa gcagaagaag 7900

 gaagagatct tgaagaccac gtgctttatc tgtggcttgg aaagagacaa 7950

 gtttgacaac aagactgtca cctttgaaga gcacatcaag gaagaacaca 8000

 acatgtggca ctatctgtgc ttcatcgtcc tggtgaaagt aaaggactcc 8050

 accgaatata ctgggcctga gagttacgtg gcagaaatga tcaaggaaag 8100

 aaaccttgac tggttcccca ggatgagagc catgtcattg gtcagcagtg 8150

 attctgaagg agaacagaat gagctgagaa acctgcagga gaagctggag 8200

 tccaccatga aacttgtcac gaacctttct ggccagctgt cggaattaaa 8250

 ggatcagatg acagaacaaa ggaagcagaa acaaagaatt ggtcttctag 8300

 gacatcctcc tcacatgaat gtcaacccac aacaaccagc ataagcaaat 8350

 gaaagaaagg aattgtattt accttttata attattatta gtgtgggtat 8400

 ggctaatgag ttctgattca cccacgaagg ttacatttat gctgaataca 8450

 tttgtaaata ctcagtttta tactgtatgt atatgattgc tactctaaag 8500

 gtttggatat atgtattgta attagaattg ttggcatgat gacatttcat 8550

 ttgtgccaaa aatattaaaa atgccttttt tggaaggact aacagaaagc 8600

 acctgatttg cacttgaacc agattataga tttaaaagta tatgacatgt 8650

 attttgtatt taaaactaga atagccagta tttatgtttt ttataaaact 8700

 gtgcaatacg aattatgcaa tcacaataca tttgtagctc ccgagtgtcc 8750

 taaagggagt gcacttcttt gaagctggtg tgttaatact atgtaataaa 8800

 tggttaactt tcaaatgatg ctgctgccaa aattatatta atagtgagtt 8850

 tcaggcccct gggcattttg taccatgtaa ttatcctctg gtgatgctgt 8900

 ttctcgttag tggcagtagt gcctccgtct cctagtgata atgctccaag 8950

 tctatgaact gttaaatcag cattcatttt aagaaaagca actttagttt 9000

 caaagatact tttaagcttc taaattgatc atttaaacta tttctttaaa 9050

 taagagagcc aaattagagg ctcatacttt agcttgtgaa gaagataatg 9100

 aattttttaa agggaacttt ctatgcaatg ttcaggataa atcgatactg 9150

 ctggccaatc agtgtcatct cctgggtaaa ttttgatgtc gcattataaa 9200

 gacatgcata attgatggtt tctagattat ctagtccaaa caatagagtt 9250

 tattttttct tcatctgaac caacatgcta cagtagctaa gaagtattaa 9300

 aactatatac atccatataa agatgaaata tgaactatct cattagaagt 9350

 catagttgac cacagacatg ttattcttct gaaagagcca cattttggtt 9400

 ttatttcttg tcacatgatt tcttttcttg atggatgaaa aatatgaaat 9450

 gaaatctttt atatctgttg cctagttttg tacatggatc tcattttaca 9500

 agagaatctc tctgcta 9517

<210> 2372
<211> 2695
<212> PRT
<213> Homo sapien

<400> 2372
 Met Ser Asp Lys Met Ser Ser Phe Leu His Ile Gly Asp Ile Cys
   1               5                  10                  15

 Ser Leu Tyr Ala Glu Gly Ser Thr Asn Gly Phe Ile Ser Thr Leu
                  20                  25                  30

 Gly Leu Val Asp Asp Arg Cys Val Val Gln Pro Glu Thr Gly Asp
                  35                  40                  45

 Leu Asn Asn Pro Pro Lys Lys Phe Arg Asp Cys Leu Phe Lys Leu
                  50                  55                  60

 Cys Pro Met Asn Arg Tyr Ser Ala Gln Lys Gln Phe Trp Lys Ala
                  65                  70                  75

 Ala Lys Pro Gly Ala Asn Ser Thr Thr Asp Ala Val Leu Leu Asn
                  80                  85                  90

 Lys Leu His His Ala Ala Asp Leu Glu Lys Lys Gln Asn Glu Thr
                  95                 100                 105

 Glu Asn Arg Lys Leu Leu Gly Thr Val Ile Gln Tyr Gly Asn Val
                 110                 115                 120

 Ile Gln Leu Leu His Leu Lys Ser Asn Lys Tyr Leu Thr Val Asn
                 125                 130                 135

 Lys Arg Leu Pro Ala Leu Leu Glu Lys Asn Ala Met Arg Val Thr
                 140                 145                 150

 Leu Asp Glu Ala Gly Asn Glu Gly Ser Trp Phe Tyr Ile Gln Pro
                 155                 160                 165

 Phe Tyr Lys Leu Arg Ser Ile Gly Asp Ser Val Val Ile Gly Asp
                 170                 175                 180

 Lys Val Val Leu Asn Pro Val Asn Ala Gly Gln Pro Leu His Ala
                 185                 190                 195

 Ser Ser His Gln Leu Val Asp Asn Pro Gly Cys Asn Glu Val Asn
                 200                 205                 210

 Ser Val Asn Cys Asn Thr Ser Trp Lys Ile Val Leu Phe Met Lys
                 215                 220                 225

 Trp Ser Asp Asn Lys Asp Asp Ile Leu Lys Gly Gly Asp Val Val
                 230                 235                 240

 Arg Leu Phe His Ala Glu Gln Glu Lys Phe Leu Thr Cys Asp Glu
                 245                 250                 255

 His Arg Lys Lys Gln His Val Phe Leu Arg Thr Thr Gly Arg Gln
                 260                 265                 270

 Ser Ala Thr Ser Ala Thr Ser Ser Lys Ala Leu Trp Glu Val Glu
                 275                 280                 285

 Val Val Gln His Asp Pro Cys Arg Gly Gly Ala Gly Tyr Trp Asn
                 290                 295                 300

 Ser Leu Phe Arg Phe Lys His Leu Ala Thr Gly His Tyr Leu Ala
                 305                 310                 315

 Ala Glu Val Asp Pro Asp Gln Asp Ala Ser Arg Ser Arg Leu Arg
                 320                 325                 330

 Asn Ala Gln Glu Lys Met Val Tyr Ser Leu Val Ser Val Pro Glu
                 335                 340                 345

 Gly Asn Asp Ile Ser Ser Ile Phe Glu Leu Asp Pro Thr Thr Leu
                 350                 355                 360

 Arg Gly Gly Asp Ser Leu Val Pro Arg Asn Ser Tyr Val Arg Leu
                 365                 370                 375

 Arg His Leu Cys Thr Asn Thr Trp Val His Ser Thr Asn Ile Pro
                 380                 385                 390

 Ile Asp Lys Glu Glu Glu Lys Pro Val Met Leu Lys Ile Gly Thr
                 395                 400                 405

 Ser Pro Val Lys Glu Asp Lys Glu Ala Phe Ala Ile Val Pro Val
                 410                 415                 420

 Ser Pro Ala Glu Val Arg Asp Leu Asp Phe Ala Asn Asp Ala Ser
                 425                 430                 435

 Lys Val Leu Gly Ser Ile Ala Gly Lys Leu Glu Lys Gly Thr Ile
                 440                 445                 450

 Thr Gln Asn Glu Arg Arg Ser Val Thr Lys Leu Leu Glu Asp Leu
                 455                 460                 465

 Val Tyr Phe Val Thr Gly Gly Thr Asn Ser Gly Gln Asp Val Leu
                 470                 475                 480

 Glu Val Val Phe Ser Lys Pro Asn Arg Glu Arg Gln Lys Leu Met
                 485                 490                 495

 Arg Glu Gln Asn Ile Leu Lys Gln Ile Phe Lys Leu Leu Gln Ala
                 500                 505                 510

 Pro Phe Thr Asp Cys Gly Asp Gly Pro Met Leu Arg Leu Glu Glu
                 515                 520                 525

 Leu Gly Asp Gln Arg His Ala Pro Phe Arg His Ile Cys Arg Leu
                 530                 535                 540

 Cys Tyr Arg Val Leu Arg His Ser Gln Gln Asp Tyr Arg Lys Asn
                 545                 550                 555

 Gln Glu Tyr Ile Ala Lys Gln Phe Gly Phe Met Gln Lys Gln Ile
                 560                 565                 570

 Gly Tyr Asp Val Leu Ala Glu Asp Thr Ile Thr Ala Leu Leu His
                 575                 580                 585

 Asn Asn Arg Lys Leu Leu Glu Lys His Ile Thr Ala Ala Glu Ile
                 590                 595                 600

 Asp Thr Phe Val Ser Leu Val Arg Lys Asn Arg Glu Pro Arg Phe
                 605                 610                 615

 Leu Asp Tyr Leu Ser Asp Leu Cys Val Ser Met Asn Lys Ser Ile
                 620                 625                 630

 Pro Val Thr Gln Glu Leu Ile Cys Lys Ala Val Leu Asn Pro Thr
                 635                 640                 645

 Asn Ala Asp Ile Leu Ile Glu Thr Lys Leu Val Leu Ser Arg Phe
                 650                 655                 660

 Glu Phe Glu Gly Val Ser Ser Thr Gly Glu Asn Ala Leu Glu Ala
                 665                 670                 675

 Gly Glu Asp Glu Glu Glu Val Trp Leu Phe Trp Arg Asp Ser Asn
                 680                 685                 690

 Lys Glu Ile Arg Ser Lys Ser Val Arg Glu Leu Ala Gln Asp Ala
                 695                 700                 705

 Lys Glu Gly Gln Lys Glu Asp Arg Asp Val Leu Ser Tyr Tyr Arg
                 710                 715                 720

 Tyr Gln Leu Asn Leu Phe Ala Arg Met Cys Leu Asp Arg Gln Tyr
                 725                 730                 735

 Leu Ala Ile Asn Glu Ile Ser Gly Gln Leu Asp Val Asp Leu Ile
                 740                 745                 750

 Leu Arg Cys Met Ser Asp Glu Asn Leu Pro Tyr Asp Leu Arg Ala
                 755                 760                 765

 Ser Phe Cys Arg Leu Met Leu His Met His Val Asp Arg Asp Pro
                 770                 775                 780

 Gln Glu Gln Val Thr Pro Val Lys Tyr Ala Arg Leu Trp Ser Glu
                 785                 790                 795

 Ile Pro Ser Glu Ile Ala Ile Asp Asp Tyr Asp Ser Ser Gly Ala
                 800                 805                 810

 Ser Lys Asp Glu Ile Lys Glu Arg Phe Ala Gln Thr Met Glu Phe
                 815                 820                 825

 Val Glu Glu Tyr Leu Arg Asp Val Val Cys Gln Arg Phe Pro Phe
                 830                 835                 840

 Ser Asp Lys Glu Lys Asn Lys Leu Thr Phe Glu Val Val Asn Leu
                 845                 850                 855

 Ala Arg Asn Leu Ile Tyr Phe Gly Phe Tyr Asn Phe Ser Asp Leu
                 860                 865                 870

 Leu Arg Leu Thr Lys Ile Leu Leu Ala Ile Leu Asp Cys Val His
                 875                 880                 885

 Val Thr Thr Ile Phe Pro Ile Ser Lys Met Ala Lys Gly Glu Glu
                 890                 895                 900

 Asn Lys Gly Ser Asn Val Met Arg Ser Ile His Gly Val Gly Glu
                 905                 910                 915

 Leu Met Thr Gln Val Val Leu Arg Gly Gly Gly Phe Leu Pro Met
                 920                 925                 930

 Thr Pro Met Ala Ala Ala Pro Glu Gly Asn Val Lys Gln Ala Glu
                 935                 940                 945

 Pro Glu Lys Glu Asp Ile Met Val Met Asp Thr Lys Leu Lys Ile
                 950                 955                 960

 Ile Glu Ile Leu Gln Phe Ile Leu Asn Val Arg Leu Asp Tyr Arg
                 965                 970                 975

 Ile Ser Cys Leu Leu Cys Ile Phe Lys Arg Glu Phe Asp Glu Ser
                 980                 985                 990

 Asn Ser Gln Thr Ser Glu Thr Ser Ser Gly Asn Ser Ser Gln Glu
                 995                1000                1005

 Gly Pro Ser Asn Val Pro Gly Ala Leu Asp Phe Glu His Ile Glu
                1010                1015                1020

 Glu Gln Ala Glu Gly Ile Phe Gly Gly Ser Glu Glu Asn Thr Pro
                1025                1030                1035

 Leu Asp Leu Asp Asp His Gly Gly Arg Thr Phe Leu Arg Val Leu
                1040                1045                1050

 Leu His Leu Thr Met His Asp Tyr Pro Pro Leu Val Ser Gly Ala
                1055                1060                1065

 Leu Gln Leu Leu Phe Arg His Phe Ser Gln Arg Gln Glu Val Leu
                1070                1075                1080

 Gln Ala Phe Lys Gln Val Gln Leu Leu Val Thr Ser Gln Asp Val
                1085                1090                1095

 Asp Asn Tyr Lys Gln Ile Lys Gln Asp Leu Asp Gln Leu Arg Ser
                1100                1105                1110

 Ile Val Glu Lys Ser Glu Leu Trp Val Tyr Lys Gly Gln Gly Pro
                1115                1120                1125

 Asp Glu Thr Met Asp Gly Ala Ser Gly Glu Asn Glu His Lys Lys
                1130                1135                1140

 Thr Glu Glu Gly Asn Asn Lys Pro Gln Lys His Glu Ser Thr Ser
                1145                1150                1155

 Ser Tyr Asn Tyr Arg Val Val Lys Glu Ile Leu Ile Arg Leu Ser
                1160                1165                1170

 Lys Leu Cys Val Gln Glu Ser Ala Ser Val Arg Lys Ser Arg Lys
                1175                1180                1185

 Gln Gln Gln Arg Leu Leu Arg Asn Met Gly Ala His Ala Val Val
                1190                1195                1200

 Leu Glu Leu Leu Gln Ile Pro Tyr Glu Lys Ala Glu Asp Thr Lys
                1205                1210                1215

 Met Gln Glu Ile Met Arg Leu Ala His Glu Phe Leu Gln Asn Phe
                1220                1225                1230

 Cys Ala Gly Asn Gln Gln Asn Gln Ala Leu Leu His Lys His Ile
                1235                1240                1245

 Asn Leu Phe Leu Asn Pro Gly Ile Leu Glu Ala Val Thr Met Gln
                1250                1255                1260

 His Ile Phe Met Asn Asn Phe Gln Leu Cys Ser Glu Ile Asn Glu
                1265                1270                1275

 Arg Val Val Gln His Phe Val His Cys Ile Glu Thr His Gly Arg
                1280                1285                1290

 Asn Val Gln Tyr Ile Lys Phe Leu Gln Thr Ile Val Lys Ala Glu
                1295                1300                1305

 Gly Lys Phe Ile Lys Lys Cys Gln Asp Met Val Met Ala Glu Leu
                1310                1315                1320

 Val Asn Ser Gly Glu Asp Val Leu Val Phe Tyr Asn Asp Arg Ala
                1325                1330                1335

 Ser Phe Gln Thr Leu Ile Gln Met Met Arg Ser Glu Arg Asp Arg
                1340                1345                1350

 Met Asp Glu Asn Ser Pro Leu Met Tyr His Ile His Leu Val Glu
                1355                1360                1365

 Leu Leu Ala Val Cys Thr Glu Gly Lys Asn Val Tyr Thr Glu Ile
                1370                1375                1380

 Lys Cys Asn Ser Leu Leu Pro Leu Asp Asp Ile Val Arg Val Val
                1385                1390                1395

 Thr His Glu Asp Cys Ile Pro Glu Val Lys Ile Ala Tyr Ile Asn
                1400                1405                1410

 Phe Leu Asn His Cys Tyr Val Asp Thr Glu Val Glu Met Lys Glu
                1415                1420                1425

 Ile Tyr Thr Ser Asn His Met Trp Lys Leu Phe Glu Asn Phe Leu
                1430                1435                1440

 Val Asp Ile Cys Arg Ala Cys Asn Asn Thr Ser Asp Arg Lys His
                1445                1450                1455

 Ala Asp Ser Ile Leu Glu Lys Tyr Val Thr Glu Ile Val Met Ser
                1460                1465                1470

 Ile Val Thr Thr Phe Phe Ser Ser Pro Phe Ser Asp Gln Ser Thr
                1475                1480                1485

 Thr Leu Gln Thr Arg Gln Pro Val Phe Val Gln Leu Leu Gln Gly
                1490                1495                1500

 Val Phe Arg Val Tyr His Cys Asn Trp Leu Met Pro Ser Gln Lys
                1505                1510                1515

 Ala Ser Val Glu Ser Cys Ile Arg Val Leu Ser Asp Val Ala Lys
                1520                1525                1530

 Ser Arg Ala Ile Ala Ile Pro Val Asp Leu Asp Ser Gln Val Asn
                1535                1540                1545

 Asn Leu Phe Leu Lys Ser His Ser Ile Val Gln Lys Thr Ala Met
                1550                1555                1560

 Asn Trp Arg Leu Ser Ala Arg Asn Ala Ala Arg Arg Asp Ser Val
                1565                1570                1575

 Leu Ala Ala Ser Arg Asp Tyr Arg Asn Ile Ile Glu Arg Leu Gln
                1580                1585                1590

 Asp Ile Val Ser Ala Leu Glu Asp Arg Leu Arg Pro Leu Val Gln
                1595                1600                1605

 Ala Glu Leu Ser Val Leu Val Asp Val Leu His Arg Pro Glu Leu
                1610                1615                1620

 Leu Phe Pro Glu Asn Thr Asp Ala Arg Arg Lys Cys Glu Ser Gly
                1625                1630                1635

 Gly Phe Ile Cys Lys Leu Ile Lys His Thr Lys Gln Leu Leu Glu
                1640                1645                1650

 Glu Asn Glu Glu Lys Leu Cys Ile Lys Val Leu Gln Thr Leu Arg
                1655                1660                1665

 Glu Met Met Thr Lys Asp Arg Gly Tyr Gly Glu Lys Gly Glu Ala
                1670                1675                1680

 Leu Arg Gln Val Leu Val Asn Arg Tyr Tyr Gly Asn Val Arg Pro
                1685                1690                1695

 Ser Gly Arg Arg Glu Ser Leu Thr Ser Phe Gly Asn Gly Pro Leu
                1700                1705                1710

 Ser Ala Gly Gly Pro Gly Lys Pro Gly Gly Gly Gly Gly Gly Ser
                1715                1720                1725

 Gly Ser Ser Ser Met Ser Arg Gly Glu Met Ser Leu Ala Glu Val
                1730                1735                1740

 Gln Cys His Leu Asp Lys Glu Gly Ala Ser Asn Leu Val Ile Asp
                1745                1750                1755

 Leu Ile Met Asn Ala Ser Ser Asp Arg Val Phe His Glu Ser Ile
                1760                1765                1770

 Leu Leu Ala Ile Ala Leu Leu Glu Gly Gly Asn Thr Thr Ile Gln
                1775                1780                1785

 His Ser Phe Phe Cys Arg Leu Thr Glu Asp Lys Lys Ser Glu Lys
                1790                1795                1800

 Phe Phe Lys Val Phe Tyr Asp Arg Met Lys Val Ala Gln Gln Glu
                1805                1810                1815

 Ile Lys Ala Thr Val Thr Val Asn Thr Ser Asp Leu Gly Asn Lys
                1820                1825                1830

 Lys Lys Asp Asp Glu Val Asp Arg Asp Ala Pro Ser Arg Lys Lys
                1835                1840                1845

 Ala Lys Glu Pro Thr Thr Gln Ile Thr Glu Glu Val Arg Asp Gln
                1850                1855                1860

 Leu Leu Glu Ala Ser Ala Ala Thr Arg Lys Ala Phe Thr Thr Phe
                1865                1870                1875

 Arg Arg Glu Ala Asp Pro Asp Asp His Tyr Gln Pro Gly Glu Gly
                1880                1885                1890

 Thr Gln Ala Thr Ala Asp Lys Ala Lys Asp Asp Leu Glu Met Ser
                1895                1900                1905

 Ala Val Ile Thr Ile Met Gln Pro Ile Leu Arg Phe Leu Gln Leu
                1910                1915                1920

 Leu Cys Glu Asn His Asn Arg Asp Leu Gln Asn Phe Leu Arg Cys
                1925                1930                1935

 Gln Asn Asn Lys Thr Asn Tyr Asn Leu Val Cys Glu Thr Leu Gln
                1940                1945                1950

 Phe Leu Asp Cys Ile Cys Gly Ser Thr Thr Gly Gly Leu Gly Leu
                1955                1960                1965

 Leu Gly Leu Tyr Ile Asn Glu Lys Asn Val Ala Leu Ile Asn Gln
                1970                1975                1980

 Thr Leu Glu Ser Leu Thr Glu Tyr Cys Gln Gly Pro Cys His Glu
                1985                1990                1995

 Asn Gln Asn Cys Ile Ala Thr His Glu Ser Asn Gly Ile Asp Ile
                2000                2005                2010

 Ile Thr Ala Leu Ile Leu Asn Asp Ile Asn Pro Leu Gly Lys Lys
                2015                2020                2025

 Arg Met Asp Leu Val Leu Glu Leu Lys Asn Asn Ala Ser Lys Leu
                2030                2035                2040

 Leu Leu Ala Ile Met Glu Ser Arg His Asp Ser Glu Asn Ala Glu
                2045                2050                2055

 Arg Ile Leu Tyr Asn Met Arg Pro Lys Glu Leu Val Glu Val Ile
                2060                2065                2070

 Lys Lys Ala Tyr Met Gln Gly Glu Val Glu Phe Glu Asp Gly Glu
                2075                2080                2085

 Asn Gly Glu Asp Gly Ala Ala Ser Pro Arg Asn Val Gly His Asn
                2090                2095                2100

 Ile Tyr Ile Leu Ala His Gln Leu Ala Arg His Asn Lys Glu Leu
                2105                2110                2115

 Gln Ser Met Leu Lys Pro Gly Gly Gln Val Asp Gly Asp Glu Ala
                2120                2125                2130

 Leu Glu Phe Tyr Ala Lys His Thr Ala Gln Ile Glu Ile Val Arg
                2135                2140                2145

 Leu Asp Arg Thr Met Glu Gln Ile Val Phe Pro Val Pro Ser Ile
                2150                2155                2160

 Cys Glu Phe Leu Thr Lys Glu Ser Lys Leu Arg Ile Tyr Tyr Thr
                2165                2170                2175

 Thr Glu Arg Asp Glu Gln Gly Ser Lys Ile Asn Asp Phe Phe Leu
                2180                2185                2190

 Arg Ser Glu Asp Leu Phe Asn Glu Met Asn Trp Gln Lys Lys Leu
                2195                2200                2205

 Arg Ala Gln Pro Val Leu Tyr Trp Cys Ala Arg Asn Met Ser Phe
                2210                2215                2220

 Trp Ser Ser Ile Ser Phe Asn Leu Ala Val Leu Met Asn Leu Leu
                2225                2230                2235

 Val Ala Phe Phe Tyr Pro Phe Lys Gly Val Arg Gly Gly Thr Leu
                2240                2245                2250

 Glu Pro His Trp Ser Gly Leu Leu Trp Thr Ala Met Leu Ile Ser
                2255                2260                2265

 Leu Ala Ile Val Ile Ala Leu Pro Lys Pro His Gly Ile Arg Ala
                2270                2275                2280

 Leu Ile Ala Ser Thr Ile Leu Arg Leu Ile Phe Ser Val Gly Leu
                2285                2290                2295

 Gln Pro Thr Leu Phe Leu Leu Gly Ala Phe Asn Val Cys Asn Lys
                2300                2305                2310

 Ile Ile Phe Leu Met Ser Phe Val Gly Asn Cys Gly Thr Phe Thr
                2315                2320                2325

 Arg Gly Tyr Arg Ala Met Val Leu Asp Val Glu Phe Leu Tyr His
                2330                2335                2340

 Leu Leu Tyr Leu Val Ile Cys Ala Met Gly Leu Phe Val His Glu
                2345                2350                2355

 Phe Phe Tyr Ser Leu Leu Leu Phe Asp Leu Val Tyr Arg Glu Glu
                2360                2365                2370

 Thr Leu Leu Asn Val Ile Lys Ser Val Thr Arg Asn Gly Arg Ser
                2375                2380                2385

 Ile Ile Leu Thr Ala Val Leu Ala Leu Ile Leu Val Tyr Leu Phe
                2390                2395                2400

 Ser Ile Val Gly Tyr Leu Phe Phe Lys Asp Asp Phe Ile Leu Glu
                2405                2410                2415

 Val Asp Arg Leu Pro Asn Glu Thr Ala Val Pro Glu Thr Gly Glu
                2420                2425                2430

 Ser Leu Ala Ser Glu Phe Leu Phe Ser Asp Val Cys Arg Val Glu
                2435                2440                2445

 Ser Gly Glu Asn Cys Ser Ser Pro Ala Pro Arg Glu Glu Leu Val
                2450                2455                2460

 Pro Ala Glu Glu Thr Glu Gln Asp Lys Glu His Thr Cys Glu Thr
                2465                2470                2475

 Leu Leu Met Cys Ile Val Thr Val Leu Ser His Gly Leu Arg Ser
                2480                2485                2490

 Gly Gly Gly Val Gly Asp Val Leu Arg Lys Pro Ser Lys Glu Glu
                2495                2500                2505

 Pro Leu Phe Ala Ala Arg Val Ile Tyr Asp Leu Leu Phe Phe Phe
                2510                2515                2520

 Met Val Ile Ile Ile Val Leu Asn Leu Ile Phe Gly Val Ile Ile
                2525                2530                2535

 Asp Thr Phe Ala Asp Leu Arg Ser Glu Lys Gln Lys Lys Glu Glu
                2540                2545                2550

 Ile Leu Lys Thr Thr Cys Phe Ile Cys Gly Leu Glu Arg Asp Lys
                2555                2560                2565

 Phe Asp Asn Lys Thr Val Thr Phe Glu Glu His Ile Lys Glu Glu
                2570                2575                2580

 His Asn Met Trp His Tyr Leu Cys Phe Ile Val Leu Val Lys Val
                2585                2590                2595

 Lys Asp Ser Thr Glu Tyr Thr Gly Pro Glu Ser Tyr Val Ala Glu
                2600                2605                2610

 Met Ile Lys Glu Arg Asn Leu Asp Trp Phe Pro Arg Met Arg Ala
                2615                2620                2625

 Met Ser Leu Val Ser Ser Asp Ser Glu Gly Glu Gln Asn Glu Leu
                2630                2635                2640

 Arg Asn Leu Gln Glu Lys Leu Glu Ser Thr Met Lys Leu Val Thr
                2645                2650                2655

 Asn Leu Ser Gly Gln Leu Ser Glu Leu Lys Asp Gln Met Thr Glu
                2660                2665                2670

 Gln Arg Lys Gln Lys Gln Arg Ile Gly Leu Leu Gly His Pro Pro
                2675                2680                2685

 His Met Asn Val Asn Pro Gln Gln Pro Ala
                2690                2695

<210> 2373
<211> 4366
<212> DNA
<213> Homo sapien

<400> 2373
 tgcattcttt gccccaaaac tctttccttt ggttgtgcta agaggtgatg 50

 cccaaggtgc accacctttc aagaactgga tcatgaacaa ctttatcctc 100

 ctggaagaac agctcatcaa gaaatcccaa caaaagagaa gaacttctcc 150

 ctcgaacttt aaagtccgct tctttgtgtt aaccaaagcc agcctggcat 200

 actttgaaga tcgtcatggg aagaagcgca cgctgaaggg gtccattgag 250

 ctctcccgaa tcaaatgtgt tgagattgtg aaaagtgaca tcagcatccc 300

 atgccactat aaatacccgt ttcaggtggt gcatgacaac tacctcctat 350

 atgtgtttgc tccagatcgt gagagccggc agcgctgggt gctggccctt 400

 aaagaagaaa cgaggaataa taacagtttg gtgcctaaat atcatcctaa 450

 tttctggatg gatgggaagt ggaggtgctg ttctcagctg gagaagcttg 500

 caacaggctg tgcccaatat gatccaacca agaatgcttc aaagaagcct 550

 cttcctccta ctcctgaaga caacaggcga ccactttggg aacctgaaga 600

 aactgtggtc attgccttat atgactacca aaccaatgat cctcaggaac 650

 tcgcactgcg gcgcaacgaa gagtactgcc tgctggacag ttctgagatt 700

 cactggtgga gagtccagga caggaatggg catgaaggat atgtaccaag 750

 cagttatctg gtggaaaaat ctccaaataa tctggaaacc tatgagtggt 800

 acaataagag tatcagccga gacaaagctg aaaaacttct tttggacaca 850

 ggcaaagaag gagccttcat ggtaagggat tccaggactg caggaacata 900

 caccgtgtct gttttcacca aggctgttgt aagtgagaac aatccctgta 950

 taaagcatta tcacatcaag gaaacaaatg acaatcctaa gcgatactat 1000

 gtggctgaaa agtatgtgtt cgattccatc cctcttctca tcaactatca 1050

 ccaacataat ggaggaggcc tggtgactcg actccggtat ccagtttgtt 1100

 ttgggaggca gaaagcccca gttacagcag ggctgagata cgggaaatgg 1150

 gtgatcgacc cctcagagct cacttttgtg caagagattg gcagtgggca 1200

 atttgggttg gtgcatctgg gctactggct caacaaggac aaggtggcta 1250

 tcaaaaccat tcgggaaggg gctatgtcag aagaggactt catagaggag 1300

 gctgaagtaa tgatgaaact ctctcatccc aaactggtgc agctgtatgg 1350

 ggtgtgcctg gagcaggccc ccatctgcct ggtgtttgag ttcatggagc 1400

 acggctgcct gtcagattat ctacgcaccc agcggggact ttttgctgca 1450

 gagaccctgc tgggcatgtg tctggatgtg tgtgagggca tggcctacct 1500

 ggaagaggca tgtgtcatcc acagagactt ggctgccaga aattgtttgg 1550

 tgggagaaaa ccaagtcatc aaggtgtctg actttgggat gacaaggttc 1600

 gttctggatg atcagtacac cagttccaca ggcaccaaat tcccggtgaa 1650

 gtgggcatcc ccagaggttt tctctttcag tcgctatagc agcaagtccg 1700

 atgtgtggtc atttggtgtg ctgatgtggg aagttttcag tgaaggcaaa 1750

 atcccgtatg aaaaccgaag caactcagag gtggtggaag acatcagtac 1800

 cggatttcgg ttgtacaagc cccggctggc ctccacacac gtctaccaga 1850

 ttatgaatca ctgctggaaa gagagaccag aagatcggcc agccttctcc 1900

 agactgctgc gtcaactggc tgaaattgca gaatcaggac tttagtagag 1950

 actgagtacc aggccacggg ctgcagatcc tgaatggagg aaggatatgt 2000

 cctcattcca tagagcatta gaagctgcca ccagcccagg accctccaga 2050

 ggcagcctgg cctgtggcat cagtccctga gtcaccatgg aagcagcatc 2100

 ctgaccacag ctggcagtca agccacagct ggagggtcag ccaccaagct 2150

 gggagctgag ccagaacagg agtgatgtct ctgcccttcc tctagcctct 2200

 tgtcacatgt ggtgcacaaa cctcaacctg acagctttca gacagcattc 2250

 ttgcacttct tagcaacaga gagagacatg agtaagaccc agattgctat 2300

 ttttattgtt atttttaaca tgaatctaaa gtttatggtt ccagggactt 2350

 tttatttgac ccaacaacac agtatcccag gatatggagg caaggggaac 2400

 aaagagcatg agtctttttc caagaaaact ggtgagttaa gtaagattag 2450

 agtgagtgtg ctctgttgct gtgatgctgt cagccacagc ttcctgccgt 2500

 agagaatgat agagcagctg ctcacacagg aggccggata ttctgagaag 2550

 cagctttatg aggttttaca gagtatgctg ctacctctct ccttgaaggg 2600

 agcatggcga gacccattgg atggattggg gtgaacagtt caggtcccat 2650

 gcttggagca ttgggtatct gatgtctgca ccagaacaag agaacctctg 2700

 acggtggaga accatgtggt gcaagaagag atcttaggtc tcttctttta 2750

 taccaagctc atcttttata ccaagctgtg caggtgacta tgcctcctct 2800

 tctgcacaga atgcttccac cagcatcctg agaagaaatg attacttctg 2850

 aaaaacatcc ttttttccag cctctgggaa tcagcccccc ctctctgcac 2900

 tatccgatcc tcatcaacag agggcagcat tgtgttggtc aatgttccct 2950

 tggcgagcaa ttgaaacttg tttaggccct agggttgagc aattttaagg 3000

 ttgagactcc aagtctccta aaattctagg agagaaataa agagtctgtt 3050

 tttgctcaaa ccatcaggat ggaaacagtc aggcactgac tggggtgctt 3100

 ccaagaggca tgagagtgcc tactctggct tgagcacttc tatatgcaag 3150

 gtgaatatgt actgagctag gagacttccc tgcaaaatct ctgttcaccc 3200

 tgggttcaca tccccatgag gtaatattat tattcccatt ttacaaataa 3250

 tgtaactgag gctttaaaaa gccaagacat ctgcccaaag tgatggaact 3300

 agaaagtcta gagctggtat tctagcccaa atctgtctga ccgcaataca 3350

 cagattcttt attcctattc gacactggct tctactgaaa atgaaacgga 3400

 ttgcagaggg aataaataca aagatggaaa gccagtaaag aagtcagtat 3450

 agaaccacta gcgaatagtg ttgctctggc acagaccact gtggttgatg 3500

 gcatggccct ccaacttgga ataggatttt ccttttccta ttctgtatcc 3550

 ttaccttggt catgttaatg actttggagt tattcagtta atgacccttt 3600

 aattctcaca accaaccagt catgttgctt gaagccattt atagacgagc 3650

 ttcaaagcaa ctttaaaaga ttcttctgta gaagtatgag ttcttccttt 3700

 aattatcatt ccaactttca gctgtagtct tcttgaacac ttcatgagga 3750

 gggacattcc ctgatataag agaggatggt gttgcaattg gctctttcta 3800

 aatcatgtga cgttttgact ggcttgagat tcagatgcat aatttttaat 3850

 tataattatt gtgaagtgga gagcctcaag ataaaactct gtcattcaga 3900

 agatgatttt actcagctta tccaaaatta tctctgttta ctttttagaa 3950

 ttttgtacat tatcttttgg gatccttaat tagagatgat ttctggaaca 4000

 ttcagtctag aaagaaaaca ttggaattga ctgatctctg tggtttggtt 4050

 tagaaaattc ccctgtgcat ggtattacct ttttcaagct cagattcatc 4100

 taatcctcaa ctgtacatgt gtacattctt cacctcctgg tgccctatcc 4150

 cgcaaaatgg gcttcctgcc tggtttttct cttctcacat tttttaaatg 4200

 gtcccctgtg tttgtagaga actcccttat acagagtttt ggttctagtt 4250

 ttatttcgta gattttgcat tttgtacctt ttgagactat gtatttatat 4300

 ttggatcaga tgcatattta ttaatgtaca gtcactgcta gtgttcaaaa 4350

 taaaaatgtt acaaat 4366

<210> 2374
<211> 620
<212> PRT
<213> Homo sapien

<400> 2374
 Met Asn Asn Phe Ile Leu Leu Glu Glu Gln Leu Ile Lys Lys Ser
   1               5                  10                  15

 Gln Gln Lys Arg Arg Thr Ser Pro Ser Asn Phe Lys Val Arg Phe
                  20                  25                  30

 Phe Val Leu Thr Lys Ala Ser Leu Ala Tyr Phe Glu Asp Arg His
                  35                  40                  45

 Gly Lys Lys Arg Thr Leu Lys Gly Ser Ile Glu Leu Ser Arg Ile
                  50                  55                  60

 Lys Cys Val Glu Ile Val Lys Ser Asp Ile Ser Ile Pro Cys His
                  65                  70                  75

 Tyr Lys Tyr Pro Phe Gln Val Val His Asp Asn Tyr Leu Leu Tyr
                  80                  85                  90

 Val Phe Ala Pro Asp Arg Glu Ser Arg Gln Arg Trp Val Leu Ala
                  95                 100                 105

 Leu Lys Glu Glu Thr Arg Asn Asn Asn Ser Leu Val Pro Lys Tyr
                 110                 115                 120

 His Pro Asn Phe Trp Met Asp Gly Lys Trp Arg Cys Cys Ser Gln
                 125                 130                 135

 Leu Glu Lys Leu Ala Thr Gly Cys Ala Gln Tyr Asp Pro Thr Lys
                 140                 145                 150

 Asn Ala Ser Lys Lys Pro Leu Pro Pro Thr Pro Glu Asp Asn Arg
                 155                 160                 165

 Arg Pro Leu Trp Glu Pro Glu Glu Thr Val Val Ile Ala Leu Tyr
                 170                 175                 180

 Asp Tyr Gln Thr Asn Asp Pro Gln Glu Leu Ala Leu Arg Arg Asn
                 185                 190                 195

 Glu Glu Tyr Cys Leu Leu Asp Ser Ser Glu Ile His Trp Trp Arg
                 200                 205                 210

 Val Gln Asp Arg Asn Gly His Glu Gly Tyr Val Pro Ser Ser Tyr
                 215                 220                 225

 Leu Val Glu Lys Ser Pro Asn Asn Leu Glu Thr Tyr Glu Trp Tyr
                 230                 235                 240

 Asn Lys Ser Ile Ser Arg Asp Lys Ala Glu Lys Leu Leu Leu Asp
                 245                 250                 255

 Thr Gly Lys Glu Gly Ala Phe Met Val Arg Asp Ser Arg Thr Ala
                 260                 265                 270

 Gly Thr Tyr Thr Val Ser Val Phe Thr Lys Ala Val Val Ser Glu
                 275                 280                 285

 Asn Asn Pro Cys Ile Lys His Tyr His Ile Lys Glu Thr Asn Asp
                 290                 295                 300

 Asn Pro Lys Arg Tyr Tyr Val Ala Glu Lys Tyr Val Phe Asp Ser
                 305                 310                 315

 Ile Pro Leu Leu Ile Asn Tyr His Gln His Asn Gly Gly Gly Leu
                 320                 325                 330

 Val Thr Arg Leu Arg Tyr Pro Val Cys Phe Gly Arg Gln Lys Ala
                 335                 340                 345

 Pro Val Thr Ala Gly Leu Arg Tyr Gly Lys Trp Val Ile Asp Pro
                 350                 355                 360

 Ser Glu Leu Thr Phe Val Gln Glu Ile Gly Ser Gly Gln Phe Gly
                 365                 370                 375

 Leu Val His Leu Gly Tyr Trp Leu Asn Lys Asp Lys Val Ala Ile
                 380                 385                 390

 Lys Thr Ile Arg Glu Gly Ala Met Ser Glu Glu Asp Phe Ile Glu
                 395                 400                 405

 Glu Ala Glu Val Met Met Lys Leu Ser His Pro Lys Leu Val Gln
                 410                 415                 420

 Leu Tyr Gly Val Cys Leu Glu Gln Ala Pro Ile Cys Leu Val Phe
                 425                 430                 435

 Glu Phe Met Glu His Gly Cys Leu Ser Asp Tyr Leu Arg Thr Gln
                 440                 445                 450

 Arg Gly Leu Phe Ala Ala Glu Thr Leu Leu Gly Met Cys Leu Asp
                 455                 460                 465

 Val Cys Glu Gly Met Ala Tyr Leu Glu Glu Ala Cys Val Ile His
                 470                 475                 480

 Arg Asp Leu Ala Ala Arg Asn Cys Leu Val Gly Glu Asn Gln Val
                 485                 490                 495

 Ile Lys Val Ser Asp Phe Gly Met Thr Arg Phe Val Leu Asp Asp
                 500                 505                 510

 Gln Tyr Thr Ser Ser Thr Gly Thr Lys Phe Pro Val Lys Trp Ala
                 515                 520                 525

 Ser Pro Glu Val Phe Ser Phe Ser Arg Tyr Ser Ser Lys Ser Asp
                 530                 535                 540

 Val Trp Ser Phe Gly Val Leu Met Trp Glu Val Phe Ser Glu Gly
                 545                 550                 555

 Lys Ile Pro Tyr Glu Asn Arg Ser Asn Ser Glu Val Val Glu Asp
                 560                 565                 570

 Ile Ser Thr Gly Phe Arg Leu Tyr Lys Pro Arg Leu Ala Ser Thr
                 575                 580                 585

 His Val Tyr Gln Ile Met Asn His Cys Trp Lys Glu Arg Pro Glu
                 590                 595                 600

 Asp Arg Pro Ala Phe Ser Arg Leu Leu Arg Gln Leu Ala Glu Ile
                 605                 610                 615

 Ala Glu Ser Gly Leu
                 620

<210> 2375
<211> 3487
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2733, 2804, 2876
<223> Unknown base

<400> 2375
 gaattccttt ttttgactga gtctccctct gtcacctagg ctggagtgca 50

 gtggcacaat cttggctcgc tgcaaccttc acccttcacc tcccaggtcg 100

 aagcgattct cctgcctcag tctcccgagt agctgggatt acaggcgtgc 150

 gccaccaaat ctggctattt ttttattatt attattttga gtagagatgg 200

 ggtttcacca tgttggccag actggtcttg aactcttggc ctcaaattat 250

 ctgcccacct cggcctccca aagtgctggg attacaggca tgagccacca 300

 tgcccagatg acaagactaa ttttttatcc ctttggttta ttggctacaa 350

 catcttcttg gaatcagagg tgaatttttt cttaccttgg gatgcctgag 400

 actaggggag tatagaattc caattggtaa ttaaggcatc tttctgctcc 450

 tgatcagaag ggcaggttag ttgggagagg tcagatggca caacagaagt 500

 caccttgtaa gtaaggcaaa gacttgaagg cattagcgtt tctcattact 550

 aggtcaataa cctgagggaa tcaatggctt tttgccgctc tacctcttgt 600

 gtatctcttt gacttttctt tctctgtcta gggcattcct gaacttgtca 650

 atcagggaca ggcattagag cccaaacagg atgctttcca aggccaagaa 700

 gcagcagtaa tgatggatca gaaggcagga ttatatggac agacataccc 750

 agcacagggg cctccaatgc aaggaggctt tcatcttcag ggacaatcac 800

 catcttttaa ctctatgatg aatcagatga accagcaagg caattttcct 850

 ctccaaggaa tgcacccacg agccaacatc atgagacccc ggacaaacac 900

 ccccaagcaa cttagaatgc agcttcagca gaggctgcag ggccagcagt 950

 ttttgaatca gagccgacag gcacttgaat tgaaaatgga aaaccctact 1000

 gctggtggtg ctgcggtgat gaggcctatg atgcagcccc aggtgagctc 1050

 ccaggagggt tttcttaatg ctcaaatggg cgcccaacgg aggagagagc 1100

 tgctaagtca tcacttccga caacagaggg tggctatgat gatgcagcag 1150

 cagcaacagc agcaacagca gcagcagcag cagcagcagc agcagcagca 1200

 gcaacagcaa cagcaacagc agcaacagga gcaaccccag gtcttcagcc 1250

 cacctcctaa tgtgactgct cccccagcat ggatggcttk yggcaggacc 1300

 cacaatgcca caagctcctc cgcaacaagt ttccaatatc caaccccaaa 1350

 ttatgggaat ggggaccaac caacaaagat ccagcctttg ggtcgagtgt 1400

 ctaagtcctc ccaatgcaat gatgtcgtca agaatggtcc ctcccagaat 1450

 cccatgatgc aacacccgca ggctgcatcc atctatcagt cctcagaaat 1500

 gaagggctgg ccatcaggaa atttggccag gaacagctcc ttttcccagc 1550

 agcagtttgc ccaccagggg aatcctgcag tgtatagtat ggtgcacatg 1600

 aatggcagca gtggtcacat gggacagatg aacatgaacc ccatgcccat 1650

 gtctggcatg cctatgggtc ctgatcagaa atactgctga catctctgca 1700

 ccaggacctc ttaaggaaac cactgtacaa atgacactgc actaggatta 1750

 ttgggaagga atcattgttc ccaggccatc catcttggga agaaaggacc 1800

 agcttttgag ctccatcaag ggtattttaa gtgatgtcat ttgagcagga 1850

 ctggatttta agccgaaggg caatatccaa cgtgtttttc ccccctcctt 1900

 cctgctgtgt atcatggtgt tcaaaacaga aatgtttttt ggcattccac 1950

 ctcctaggga tataattctg gagacatgga gtgttactga tcataaaact 2000

 tttgtgtcac ttttttctgc cttgctagcc aaaatctctt aaatacacgt 2050

 aggtgggcca gagaacattg gaagaatcaa gagagattag aatatctggt 2100

 ttctctagtt gcagtattgg acaaagagca tagtcccagc cttcaggtgt 2150

 agtagttctg tgttgaccct ttgtccagtg gaattggtga ttctgaattg 2200

 tcctttacta atgttgttga gttgctctgt ccctattatt tgccctagcc 2250

 tttctcctaa tggggttttc atttgccatt catgtccctg taaaacttca 2300

 cctccaggaa ctgtcatgga tgtccaaatg gctttgcaga aaggaaatga 2350

 gatgacagta tttaatcgca gcagtagcaa acttttcaca tgctaatgtg 2400

 cagctgagtg cactttattt aaaaagaatg gataaatgca atattcttga 2450

 ggtcttgagg gaatagtgaa acacattcct ggtttttgcc tacacttacg 2500

 tgttagacaa gaactatgat tttttttttt aaagtactgg tgtcaccctt 2550

 tgcctatatg gtagagcaat aatgcttttt aaaaataaac ttctgaaaac 2600

 ccaaggccag gtactgcatt ctgaatcaga atctcgcagt gtttctgtga 2650

 atagattttt ttgtaaatat gacctttaag atattgtatt atgtaaaata 2700

 tgtatatacc ttttttttgt aggtgcacag cgnctcattt ttacagagtt 2750

 tgtgaagcta aatatttaac attgttgatt tcagtaagct gtgtggtgag 2800

 gctnccagtg gaagagacat cccttgactt ttgtggcctg ggggaggggt 2850

 agtgctccac agcttttcct tccccncccc ccagccttag atgcctcgct 2900

 cttttcaatc tcttaatcta aatgcttttt aaagagatta tttgtttaga 2950

 tgtaggcatt ttaatttttt aaaaattcct ctaccagaac taagcacttt 3000

 gttaatttgg ggggggagaa tagatatggg gagaaaaaac ttaaaaaaaa 3050

 aatcaggaat taaaaaaagc gagcaatttg aagagaatct tttggatttt 3100

 aagcagtccg aaataatagc aattcatggg ctgtgtgtgt gtgtgtatgt 3150

 gtgtgtgtgt gtgtgtgaat gtttaagtat gttacctttt catccccttt 3200

 aggagcgttt tcagattttg gttgctaaga cctgaatccc atattgagat 3250

 ctcgagtaga atccttggtg tggtttctgg tgtctgctca gctgtcccct 3300

 cattctacta atgtgatgct ttcattatgt ccctgtggat tagaatagtg 3350

 tcagttattt cttaagtaac tcagtaccca gaacaaccag ttttactgtg 3400

 attcagagcc acagtctaac tgagcacctt ttaaacccct ccctcttctg 3450

 ccccctacca cttttctgct gttgcctctc ggaattc 3487

<210> 2376
<211> 326
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 194
<223> unknown amino acid

<220>
<221> Unsure
<222> 2733, 2804, 2876
<223> Unknown amino acid

<400> 2376
 Met Met Asp Gln Lys Ala Gly Leu Tyr Gly Gln Thr Tyr Pro Ala
   1               5                  10                  15

 Gln Gly Pro Pro Met Gln Gly Gly Phe His Leu Gln Gly Gln Ser
                  20                  25                  30

 Pro Ser Phe Asn Ser Met Met Asn Gln Met Asn Gln Gln Gly Asn
                  35                  40                  45

 Phe Pro Leu Gln Gly Met His Pro Arg Ala Asn Ile Met Arg Pro
                  50                  55                  60

 Arg Thr Asn Thr Pro Lys Gln Leu Arg Met Gln Leu Gln Gln Arg
                  65                  70                  75

 Leu Gln Gly Gln Gln Phe Leu Asn Gln Ser Arg Gln Ala Leu Glu
                  80                  85                  90

 Leu Lys Met Glu Asn Pro Thr Ala Gly Gly Ala Ala Val Met Arg
                  95                 100                 105

 Pro Met Met Gln Pro Gln Val Ser Ser Gln Glu Gly Phe Leu Asn
                 110                 115                 120

 Ala Gln Met Gly Ala Gln Arg Arg Arg Glu Leu Leu Ser His His
                 125                 130                 135

 Phe Arg Gln Gln Arg Val Ala Met Met Met Gln Gln Gln Gln Gln
                 140                 145                 150

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                 155                 160                 165

 Gln Gln Gln Gln Gln Gln Gln Gln Glu Gln Pro Gln Val Phe Ser
                 170                 175                 180

 Pro Pro Pro Asn Val Thr Ala Pro Pro Ala Trp Met Ala Xaa Gly
                 185                 190                 195

 Arg Thr His Asn Ala Thr Ser Ser Ser Ala Thr Ser Phe Gln Tyr
                 200                 205                 210

 Pro Thr Pro Asn Tyr Gly Asn Gly Asp Gln Pro Thr Lys Ile Gln
                 215                 220                 225

 Pro Leu Gly Arg Val Ser Lys Ser Ser Gln Cys Asn Asp Val Val
                 230                 235                 240

 Lys Asn Gly Pro Ser Gln Asn Pro Met Met Gln His Pro Gln Ala
                 245                 250                 255

 Ala Ser Ile Tyr Gln Ser Ser Glu Met Lys Gly Trp Pro Ser Gly
                 260                 265                 270

 Asn Leu Ala Arg Asn Ser Ser Phe Ser Gln Gln Gln Phe Ala His
                 275                 280                 285

 Gln Gly Asn Pro Ala Val Tyr Ser Met Val His Met Asn Gly Ser
                 290                 295                 300

 Ser Gly His Met Gly Gln Met Asn Met Asn Pro Met Pro Met Ser
                 305                 310                 315

 Gly Met Pro Met Gly Pro Asp Gln Lys Tyr Cys
                 320                 325

<210> 2377
<211> 1373
<212> DNA
<213> Homo sapien

<400> 2377
 gggaggagag aaaagccatg gccgacaagg tcctgaagga gaagagaaag 50

 ctgtttatcc gttccatggg tgaaggtaca ataaatggct tactggatga 100

 attattacag acaagggtgc tgaacaagga agagatggag aaagtaaaac 150

 gtgaaaatgc tacagttatg gataagaccc gagctttgat tgactccgtt 200

 attccgaaag gggcacaggc atgccaaatt tgcatcacat acatttgtga 250

 agaagacagt tacctggcag ggacgctggg actctcagca gatcaaacat 300

 ctggaaatta ccttaatatg caagactctc aaggagtact ttcttccttt 350

 ccagctcctc aggcagtgca ggacaaccca gctatgccca catcctcagg 400

 ctcagaaggg aatgtcaagc tttgctccct agaagaagct caaaggatat 450

 ggaaacaaaa gtcggcagag atttatccaa taatggacaa gtcaagccgc 500

 acacgtcttg ctctcattat ctgcaatgaa gaatttgaca gtattcctag 550

 aagaactgga gctgaggttg acatcacagg catgacaatg ctgctacaaa 600

 atctggggta cagcgtagat gtgaaaaaaa atctcactgc ttcggacatg 650

 actacagagc tggaggcatt tgcacaccgc ccagagcaca agacctctga 700

 cagcacgttc ctggtgttca tgtctcatgg tattcgggaa ggcatttgtg 750

 ggaagaaaca ctctgagcaa gtcccagata tactacaact caatgcaatc 800

 tttaacatgt tgaataccaa gaactgccca agtttgaagg acaaaccgaa 850

 ggtgatcatc atccaggcct gccgtggtga cagccctggt gtggtgtggt 900

 ttaaagattc agtaggagtt tctggaaacc tatctttacc aactacagaa 950

 gagtttgagg atgatgctat taagaaagcc cacatagaga aggattttat 1000

 cgctttctgc tcttccacac cagataatgt ttcttggaga catcccacaa 1050

 tgggctctgt ttttattgga agactcattg aacatatgca agaatatgcc 1100

 tgttcctgtg atgtggagga aattttccgc aaggttcgat tttcatttga 1150

 gcagccagat ggtagagcgc agatgcccac cactgaaaga gtgactttga 1200

 caagatgttt ctacctcttc ccaggacatt aaaataagga aactgtatga 1250

 atgtctgtgg gcaggaagtg aagagatcgt tctgtaaaag gtttttggaa 1300

 ttatgtctgc tgaataataa actttttttg aaataataaa tctggtagaa 1350

 aaatgaaaaa aaaaaaaaaa aaa 1373

<210> 2378
<211> 404
<212> PRT
<213> Homo sapien

<400> 2378
 Met Ala Asp Lys Val Leu Lys Glu Lys Arg Lys Leu Phe Ile Arg
   1               5                  10                  15

 Ser Met Gly Glu Gly Thr Ile Asn Gly Leu Leu Asp Glu Leu Leu
                  20                  25                  30

 Gln Thr Arg Val Leu Asn Lys Glu Glu Met Glu Lys Val Lys Arg
                  35                  40                  45

 Glu Asn Ala Thr Val Met Asp Lys Thr Arg Ala Leu Ile Asp Ser
                  50                  55                  60

 Val Ile Pro Lys Gly Ala Gln Ala Cys Gln Ile Cys Ile Thr Tyr
                  65                  70                  75

 Ile Cys Glu Glu Asp Ser Tyr Leu Ala Gly Thr Leu Gly Leu Ser
                  80                  85                  90

 Ala Asp Gln Thr Ser Gly Asn Tyr Leu Asn Met Gln Asp Ser Gln
                  95                 100                 105

 Gly Val Leu Ser Ser Phe Pro Ala Pro Gln Ala Val Gln Asp Asn
                 110                 115                 120

 Pro Ala Met Pro Thr Ser Ser Gly Ser Glu Gly Asn Val Lys Leu
                 125                 130                 135

 Cys Ser Leu Glu Glu Ala Gln Arg Ile Trp Lys Gln Lys Ser Ala
                 140                 145                 150

 Glu Ile Tyr Pro Ile Met Asp Lys Ser Ser Arg Thr Arg Leu Ala
                 155                 160                 165

 Leu Ile Ile Cys Asn Glu Glu Phe Asp Ser Ile Pro Arg Arg Thr
                 170                 175                 180

 Gly Ala Glu Val Asp Ile Thr Gly Met Thr Met Leu Leu Gln Asn
                 185                 190                 195

 Leu Gly Tyr Ser Val Asp Val Lys Lys Asn Leu Thr Ala Ser Asp
                 200                 205                 210

 Met Thr Thr Glu Leu Glu Ala Phe Ala His Arg Pro Glu His Lys
                 215                 220                 225

 Thr Ser Asp Ser Thr Phe Leu Val Phe Met Ser His Gly Ile Arg
                 230                 235                 240

 Glu Gly Ile Cys Gly Lys Lys His Ser Glu Gln Val Pro Asp Ile
                 245                 250                 255

 Leu Gln Leu Asn Ala Ile Phe Asn Met Leu Asn Thr Lys Asn Cys
                 260                 265                 270

 Pro Ser Leu Lys Asp Lys Pro Lys Val Ile Ile Ile Gln Ala Cys
                 275                 280                 285

 Arg Gly Asp Ser Pro Gly Val Val Trp Phe Lys Asp Ser Val Gly
                 290                 295                 300

 Val Ser Gly Asn Leu Ser Leu Pro Thr Thr Glu Glu Phe Glu Asp
                 305                 310                 315

 Asp Ala Ile Lys Lys Ala His Ile Glu Lys Asp Phe Ile Ala Phe
                 320                 325                 330

 Cys Ser Ser Thr Pro Asp Asn Val Ser Trp Arg His Pro Thr Met
                 335                 340                 345

 Gly Ser Val Phe Ile Gly Arg Leu Ile Glu His Met Gln Glu Tyr
                 350                 355                 360

 Ala Cys Ser Cys Asp Val Glu Glu Ile Phe Arg Lys Val Arg Phe
                 365                 370                 375

 Ser Phe Glu Gln Pro Asp Gly Arg Ala Gln Met Pro Thr Thr Glu
                 380                 385                 390

 Arg Val Thr Leu Thr Arg Cys Phe Tyr Leu Phe Pro Gly His
                 395                 400

<210> 2379
<211> 4586
<212> DNA
<213> Homo sapien

<400> 2379
 agaacgatgg cctttctgcg gtgtctgcga ccgggaccaa ggcggagcaa 50

 agtcgccggg ggtgtggggt gttccacgct atgttgggag tgttcgcttt 100

 cgagcttatt gcaggagtga ccaggacact acctcctaga agtaatgccc 150

 acagaaagcg caagttgttc gactgctcgc caaacaaaac agaagcgcaa 200

 atcccatagc ctttctatac gaagaactaa cagctcggag caggagagga 250

 cgggactgcc aagagacatg ttagaaggac aagattctaa actgccttcc 300

 tcggttcgca gtacacttct ggaactgttt ggtcaaatag aaagagaatt 350

 tgaaaacctt tatatcgaaa acttagaatt acgtagagaa atcgacactc 400

 ttaatgaacg tttagctgct gaaggacaag cgattgatgg agcagagctg 450

 agtaagggcc aactcaaaac aaaagccagt cacagcacca gccagctctc 500

 ccagaaactg aagaccactt acaaggcttc caccagcaag attgtctcca 550

 gctttaagac cacgacatcg agagctgcct gccagctcgt gaaggagtac 600

 atcggccacc gggacggcat ctgggatgtc agcgtggcca agacacagcc 650

 agtggtgctc gggactgcat cagccgatca cacggctttg ctgtggagca 700

 tagagacagg gaagtgccta gtcaagtacg caggccacgt gggctcagta 750

 aattctatca aatttcatcc ctcagagcag ttggctctca ctgcttctgg 800

 agatcagact gctcatatct ggagatacgc ggtgcagctg ccgacacccc 850

 agcctgttgc tgacactagt atatctgggg aagatgaagt agagtgctct 900

 gacaaggacg agcccgacct cgatggggat gtgtccagcg actcccccac 950

 catccgcgtc ccactgacat ccctcaagag ccaccagggc gtggtcatcg 1000

 cctccgactg gctggttggg gggaagcagg ctgtgactgc ctcctgggac 1050

 cggacggcaa acctgtacga cgtggagacg tccgagctcg ttcactctct 1100

 gacagggcac gaccaggagt tgacgcactg ctgcacacac cccacccagc 1150

 ggctcgtggt gacctcctcc cgtgacacga ctttccgcct ctgggatttc 1200

 agggacccct ccatccactc ggtgaatgtt ttccagggac acacggacac 1250

 tgtgacttct gccgtgttca ccgtgggaga caacgtggtt tcaggcagcg 1300

 atgaccgcac ggtgaaagtc tgggacttga aaaatatgag atcccccatt 1350

 gcaactattc gcacggactc tgccattaac aggatcaatg tatgtgtcgg 1400

 ccaaaaaatc atagccctcc cccatgacaa ccgacaagtg agactgtttg 1450

 atatgtcagg agtgcgcctg gcgcggcttc cccggagcag ccgacagggc 1500

 cacaggagaa tggtatgctg ctcggcatgg agtgaagacc accccgtgtg 1550

 caatctgttc acctgtgggt ttgaccggca agccattggt tggaacatca 1600

 acatccctgc attgctacaa gaaaaataag gacaccggca gcccttagtt 1650

 tcactgtttg ccagcacaga cctttgatgg gtgcaggctt ttctgcgtat 1700

 taatcagcca tttttgtgag agtttgaccc tggaaagggt gctttgtata 1750

 tgttcttttc acatagtgcc cagcttgcat gaaatgtaca gagaaatgtg 1800

 tggtcgtatt ttttactttt gtcttgtata tgtatgtata ttgggtcctc 1850

 tgggcagtag aggcaaagct cacctcccat gtagcacatg aaatgcttgt 1900

 gagttgttga cattggacag gtgaacagta gggcattaca tttgtgtgaa 1950

 ttaaatgtga acttctgtat tacgttgcgg cgtcggctgt cctgcgttcc 2000

 ctggagtaac tgtacgtatc tgcctttgct gggaagactg tgaggctgcc 2050

 tgtgttggct ggcgaccagc aggattgctc caggattttg tgtttacctc 2100

 gcgtgaagtt cagcacgtgc tgtcgtgtag tcagcttcta ctctaatttc 2150

 tgttacagtt ctgcaaaggt aacctggagt ttagaagtta aaaaaaagca 2200

 tgggatgttg gatttgcacc atttggagtt tctttaggaa agaaaagttt 2250

 tctgcttttt tatagaaaat catttcagtc tcctgaggtc tcatgctagc 2300

 aaattttgaa ataggattct aatcactgat ttcaaatatt aagcaaaatg 2350

 taaagcactt taatttatag ctatggttat aaacaggttt tagatgtttc 2400

 aaatgacttg tccactgaat gtcacttgac cttgataaga ggccgcctgc 2450

 acacagagcc cagttaattc tccgcacctc ggttgtgtgc ttccgaatgg 2500

 gctcactccc gtggtggtgt ttgagagcca acaacactac ctcagagacg 2550

 ggtctttggg aaactttggg tctcactgtt gcctggctgg agcactttgg 2600

 tttatagctg gaatactgag ttcagttcag aaggcaggaa agacagtcac 2650

 accgacgtgt cctgaaggtg taggctctcc acttaggcgc acaagctgac 2700

 ggctgcagcc agcaggcccc ggtgacgaga cacttccagg tcttgtggtg 2750

 gggacgcctc tcagtgccag tcccgccact gctgagtgag cctggtgttc 2800

 ttgccttctt ggaaattact gctcacctgg tatctgtacg ttaatgtttc 2850

 ttgctgagtt acagttttga taaagaggct ctcatttcct gtgtcttgta 2900

 tattcagtcc tttcaatacg tccacctgga ggctcaccac ttggagagac 2950

 acaggaaggt aatatttaca gctgtcatgt gacatcccca ggtctttgtg 3000

 ttttgccctg ttttacggtg aggtaggagg gaacccatct ggggaccggt 3050

 aggtgcaggt gcagtaggac gtgggacttt tggacccgtc ctttggtgca 3100

 gctcgccagg gatgagaggc acctccctac ttgggtcttc aggagctggt 3150

 ccaaggagct tcgaatctaa gtcatctaga atgaccctga aatgactgac 3200

 agccccgggc ccaagaaaaa cccataacca cctcagatgg atctgacgtg 3250

 gctaagggac aaacagcaaa tatttcagtc attttgattt tacaaataaa 3300

 aaatgtgttg tgtttttgtc cgacattatt tcctgactgc actgttctga 3350

 gaatggagtc cacctggtcc ctctggttga ttagaatctc aggtttcagc 3400

 tcctgctgtc ctgagcgaac ttgcctgatg cagggctgtg ctgtgtccag 3450

 atgttgctgg ggcctcactt tttctcttgg ctggaggtcc aattgccaga 3500

 gcctcccaca ctgcacatac aaaggtctga gcccagggca gcttctgggg 3550

 ccactgcaca ggccacctgc ttgggttcct cggagtttaa tttgaaagtc 3600

 tgggtgtctt aggatgatgg ttaggaacat tgaaaaatgg ctgcaaatag 3650

 ccaaatcaaa cttaagaacc agatctctgc cagattaaac atttttgaag 3700

 cttttaaaag tcaatattcc tagtggccac tgagttccag gcacactggt 3750

 gccctttact gccacagctg ctcaccttgt ctggcaaact ggagggacct 3800

 cagaaactgg actcctgcat gtccttgggg gcgcagccct gtggtgctca 3850

 ggcagagctc tcaggagccg gggcaccttg ctgttcgctg ctgtgtcgtc 3900

 ttctaatgtg agctcatcca ctgctgctgc agcgtggtga tcaggagtca 3950

 cagacaagat cggggatggt gtgtgtgtgc gtgtgtgtgt gtgtgtgtgt 4000

 gcacgtgtgt gtggctaaat taagtcatac tgtcaaccac acgtgatctc 4050

 gtctgaaaca gtgtttggaa gtgggaacag ttttgtcctg tatgctgatg 4100

 tgtccagaat ttcatttaat gatagacgga aaatgtgtgg ttactgaaaa 4150

 ctgtatatga tacagaattt cataagagcc atgctgttgg gcaaagcaac 4200

 tctttttcaa ccactgctca tcagtttctg tagagacaaa aactctgtac 4250

 atattttgga atctgaagaa tcctatgtaa atcatttgtt acttaagtct 4300

 gtgaaaaaca tatttctttg gaggaaaatg tatgcattta taagtgttcc 4350

 atggaatcag tttttattgt atcgatataa ttgtctctaa gtgttgactg 4400

 tcttcattgc aatatgaaat tcattaaaat gtccatgttc cataattact 4450

 attataaaag ctttgtgtta ttgggagtct tattattttt atagtttttc 4500

 atgttttgct ttggtgaaac attgtgaatg actatataaa catcacgatg 4550

 agctagaaat tgaacaaata taatactggt cactcg 4586

<210> 2380
<211> 494
<212> PRT
<213> Homo sapien

<400> 2380
 Met Pro Thr Glu Ser Ala Ser Cys Ser Thr Ala Arg Gln Thr Lys
   1               5                  10                  15

 Gln Lys Arg Lys Ser His Ser Leu Ser Ile Arg Arg Thr Asn Ser
                  20                  25                  30

 Ser Glu Gln Glu Arg Thr Gly Leu Pro Arg Asp Met Leu Glu Gly
                  35                  40                  45

 Gln Asp Ser Lys Leu Pro Ser Ser Val Arg Ser Thr Leu Leu Glu
                  50                  55                  60

 Leu Phe Gly Gln Ile Glu Arg Glu Phe Glu Asn Leu Tyr Ile Glu
                  65                  70                  75

 Asn Leu Glu Leu Arg Arg Glu Ile Asp Thr Leu Asn Glu Arg Leu
                  80                  85                  90

 Ala Ala Glu Gly Gln Ala Ile Asp Gly Ala Glu Leu Ser Lys Gly
                  95                 100                 105

 Gln Leu Lys Thr Lys Ala Ser His Ser Thr Ser Gln Leu Ser Gln
                 110                 115                 120

 Lys Leu Lys Thr Thr Tyr Lys Ala Ser Thr Ser Lys Ile Val Ser
                 125                 130                 135

 Ser Phe Lys Thr Thr Thr Ser Arg Ala Ala Cys Gln Leu Val Lys
                 140                 145                 150

 Glu Tyr Ile Gly His Arg Asp Gly Ile Trp Asp Val Ser Val Ala
                 155                 160                 165

 Lys Thr Gln Pro Val Val Leu Gly Thr Ala Ser Ala Asp His Thr
                 170                 175                 180

 Ala Leu Leu Trp Ser Ile Glu Thr Gly Lys Cys Leu Val Lys Tyr
                 185                 190                 195

 Ala Gly His Val Gly Ser Val Asn Ser Ile Lys Phe His Pro Ser
                 200                 205                 210

 Glu Gln Leu Ala Leu Thr Ala Ser Gly Asp Gln Thr Ala His Ile
                 215                 220                 225

 Trp Arg Tyr Ala Val Gln Leu Pro Thr Pro Gln Pro Val Ala Asp
                 230                 235                 240

 Thr Ser Ile Ser Gly Glu Asp Glu Val Glu Cys Ser Asp Lys Asp
                 245                 250                 255

 Glu Pro Asp Leu Asp Gly Asp Val Ser Ser Asp Ser Pro Thr Ile
                 260                 265                 270

 Arg Val Pro Leu Thr Ser Leu Lys Ser His Gln Gly Val Val Ile
                 275                 280                 285

 Ala Ser Asp Trp Leu Val Gly Gly Lys Gln Ala Val Thr Ala Ser
                 290                 295                 300

 Trp Asp Arg Thr Ala Asn Leu Tyr Asp Val Glu Thr Ser Glu Leu
                 305                 310                 315

 Val His Ser Leu Thr Gly His Asp Gln Glu Leu Thr His Cys Cys
                 320                 325                 330

 Thr His Pro Thr Gln Arg Leu Val Val Thr Ser Ser Arg Asp Thr
                 335                 340                 345

 Thr Phe Arg Leu Trp Asp Phe Arg Asp Pro Ser Ile His Ser Val
                 350                 355                 360

 Asn Val Phe Gln Gly His Thr Asp Thr Val Thr Ser Ala Val Phe
                 365                 370                 375

 Thr Val Gly Asp Asn Val Val Ser Gly Ser Asp Asp Arg Thr Val
                 380                 385                 390

 Lys Val Trp Asp Leu Lys Asn Met Arg Ser Pro Ile Ala Thr Ile
                 395                 400                 405

 Arg Thr Asp Ser Ala Ile Asn Arg Ile Asn Val Cys Val Gly Gln
                 410                 415                 420

 Lys Ile Ile Ala Leu Pro His Asp Asn Arg Gln Val Arg Leu Phe
                 425                 430                 435

 Asp Met Ser Gly Val Arg Leu Ala Arg Leu Pro Arg Ser Ser Arg
                 440                 445                 450

 Gln Gly His Arg Arg Met Val Cys Cys Ser Ala Trp Ser Glu Asp
                 455                 460                 465

 His Pro Val Cys Asn Leu Phe Thr Cys Gly Phe Asp Arg Gln Ala
                 470                 475                 480

 Ile Gly Trp Asn Ile Asn Ile Pro Ala Leu Leu Gln Glu Lys
                 485                 490

<210> 2381
<211> 1851
<212> DNA
<213> Homo sapien

<400> 2381
 gaaaagccgc cggtatttct ccacctggct ctcctctacc tccaggcagg 50

 cgcacccgag gtccccctcc caccccacct tctgccctcc cgcacacttg 100

 gaccagtgct gttgacccgg aagcggacat ttctgcagct attctaagca 150

 cacgtcggcg gagggagcgg gacgtggcca gcggtcagcg gcgaaggagg 200

 caggccctgc gcggggatca cggaagccct gtgattcacc atgaagttcc 250

 agtacaagga ggtccatccc tttgagtatc ggaaaaagga aggagaaaag 300

 atccggaaga aatatccgga cagggtcccc ttgattgtag agaaggctcc 350

 aaaagcaagg gtgcctgatc tggacaggag gaagtaccta gtgccctccg 400

 accttaccga tggccagttc taccttttaa tccggaagag aatccacctg 450

 agacctgagg acgccttatt cttctttgtc aacaacacta tccctcccac 500

 tagtgctacc atgggccaac tatatgagga cagtcatgag gaagatgatt 550

 ttctgtatgt ggcctacagt aatgagagtg tctatgggaa atgagtggtt 600

 ggaagcccag cagatggaag cacctggact taggggtagg ggaggggtgt 650

 gtgtgtgact tggggaaaga gagggcggct cccaccgtga ggagacagaa 700

 ggtgaagaca tatagaaact ttacaccgca cacaccgtca acgcattttc 750

 acatgctcaa ctgatatttt ttgttgcttc cttggcccag ggagaaagca 800

 tgtcaggaca gagctgttgg attggctttg atagaggaat ggggatgatg 850

 taattttatg gcattcctga gatttaattt ttgtgcagtt tcatagaaag 900

 gtcggtcagg aggtggacaa gttggggtca gagatgatgg cagtccagca 950

 gcaactccct gtgctccctt ctctttgggc agagattctg tttttgacag 1000

 ttgcacaaga caggtaggga aaggggactt gtggtagtgg gccatacctg 1050

 gggacgaaaa gagacccact gtaattgatg catcgtggcc cccgatcttc 1100

 cgtatcccac acttcttttc tcccatccca gttgcaatct cactcacaaa 1150

 catcacagta ccaccccagg ggcggcagta gacaccaacc cagaaattta 1200

 gacagggatc tcttatcttt ggaaaatagg ggttaggcat gagggtggtt 1250

 atgattaaga agataatttt gttgttaaat agcattaaac tggaattgac 1300

 agagtgagtt gagcatctct gtctaacctg ctctttctct ctggtgctcc 1350

 tcatctcacc cctaccttgg aatttaataa gcttcaggca tttccaattg 1400

 cagactaaaa ccacttctac catctcctct agtattttcc atgtatcagg 1450

 acagagatgt cttatgtagg gaaggggcag gtatgaagtg aggtagatta 1500

 tctatacctc tcactcattc aggattctcg ctcccatgct gctgtccctt 1550

 cattctcaca ctcacaggaa tgctatgtga tggccagctg cttcccttct 1600

 tggttatcca ctgcagctgc tagttagaaa ggtttgcagg gatgactttt 1650

 agtaaatcat ggggatttta ttgatttatt atcacttata ggattttgtg 1700

 gggtgggagt ggggagcagg aattgcactc agacatgaca tttcaattca 1750

 tctctgcaaa tgaaaagggt tcttcctctt gggggaaatc tgtgtgtcag 1800

 ttctgtcagc tgcaagttct tgtgtaatga agtcaatgct gtcaggccaa 1850

 g 1851

<210> 2382
<211> 117
<212> PRT
<213> Homo sapien

<400> 2382
 Met Lys Phe Gln Tyr Lys Glu Val His Pro Phe Glu Tyr Arg Lys
   1               5                  10                  15

 Lys Glu Gly Glu Lys Ile Arg Lys Lys Tyr Pro Asp Arg Val Pro
                  20                  25                  30

 Leu Ile Val Glu Lys Ala Pro Lys Ala Arg Val Pro Asp Leu Asp
                  35                  40                  45

 Arg Arg Lys Tyr Leu Val Pro Ser Asp Leu Thr Asp Gly Gln Phe
                  50                  55                  60

 Tyr Leu Leu Ile Arg Lys Arg Ile His Leu Arg Pro Glu Asp Ala
                  65                  70                  75

 Leu Phe Phe Phe Val Asn Asn Thr Ile Pro Pro Thr Ser Ala Thr
                  80                  85                  90

 Met Gly Gln Leu Tyr Glu Asp Ser His Glu Glu Asp Asp Phe Leu
                  95                 100                 105

 Tyr Val Ala Tyr Ser Asn Glu Ser Val Tyr Gly Lys
                 110                 115

<210> 2383
<211> 1953
<212> DNA
<213> Homo sapien

<400> 2383
 gcagaccttg cttcatgagc aagctcatct ctggaacaaa ctggcaaagc 50

 atctctgctg gtgttcatca gaacagacac catggcagag catgattacc 100

 atgaagacta tgggttcagc agtttcaatg acagcagcca ggaggagcat 150

 caagacttcc tgcagttcag caaggtcttt ctgccctgca tgtacctggt 200

 ggtgtttgtc tgtggtctgg tggggaactc tctggtgctg gtcatatcca 250

 tcttctacca taagttgcag agcctgacgg atgtgttcct ggtgaaccta 300

 cccctggctg acctggtgtt tgtctgcact ctgcccttct gggcctatgc 350

 aggcatccat gaatgggtgt ttggccaggt catgtgcaag agcctactgg 400

 gcatctacac tattaacttc tacacgtcca tgctcatcct cacctgcatc 450

 actgtggatc gtttcattgt agtggttaag gccaccaagg cctacaacca 500

 gcaagccaag aggatgacct ggggcaaggt caccagcttg ctcatctggg 550

 tgatatccct gctggtttcc ttgccccaaa ttatctatgg caatgtcttt 600

 aatctcgaca agctcatatg tggttaccat gacgaggcaa tttccactgt 650

 ggttcttgcc acccagatga cactggggtt cttcttgcca ctgctcacca 700

 tgattgtctg ctattcagtc ataatcaaaa cactgcttca tgctggaggc 750

 ttccagaagc acagatctct aaagatcatc ttcctggtga tggctgtgtt 800

 cctgctgacc cagatgccct tcaacctcat gaagttcatc cgcagcacac 850

 actgggaata ctatgccatg accagctttc actacaccat catggtgaca 900

 gaggccatcg catacctgag ggcctgcctt aaccctgtgc tctatgcctt 950

 tgtcagcctg aagtttcgaa agaacttctg gaaacttgtg aaggacattg 1000

 gttgcctccc ttaccttggg gtctcacatc aatggaaatc ttctgaggac 1050

 aattccaaga ctttttctgc ctcccacaat gtggaggcca ccagcatgtt 1100

 ccagttatag gccttgccag ggtttcgaga agctgctctg gaatttgcaa 1150

 gtcatggctg tgccctcttg atgtggtgag gcaggctttg tttatagctt 1200

 gcgcattctc atggagaagt tatcagacac tctggctggt ttggaatgct 1250

 tcttctcagg catgaacatg tactgttctc ttcttgaaca ctcatgctga 1300

 aagcccaagt agggggtcta aaatttttaa ggactttcct tcctccatct 1350

 ccaagaatgc tgaaaccaag ggggatgaca tgtgactcct atgatctcag 1400

 gttctccttg attgggactg gggctgaagg ttgaagaggt gagcacggcc 1450

 aacaaagctg ttgatggtag gtggcacact gggtgcccaa gctcagaagg 1500

 ctcttctgac tactgggcaa agagtgtaga tcagagcagc agtgaaaaca 1550

 agtgctggca ccaccaggca cctcacagaa atgagatcag gctctgcctc 1600

 accttggggc ttgacttttg tataggtaga tgttcagatt gctttgatta 1650

 atccagaata actagcacca gggactatga atgggcaaaa ctgaattata 1700

 agaggctgat aattccagtg gtccatggaa tgcttgaaaa atgtgcaaaa 1750

 cagcgtttaa gactgtaatg aatctaagca gcatttctga agtggactct 1800

 ttggtggctt tgcattttaa aaatgaaatt ttccaatgtc tgccacacaa 1850

 acgtatgtaa atgtatatac ccacacacat acacacatat gtcatatatt 1900

 actagcatat gagtttcata gctaagaaat aaaactgtta aagtctccaa 1950

 act 1953

<210> 2384
<211> 342
<212> PRT
<213> Homo sapien

<400> 2384
 Met Ala Glu His Asp Tyr His Glu Asp Tyr Gly Phe Ser Ser Phe
   1               5                  10                  15

 Asn Asp Ser Ser Gln Glu Glu His Gln Asp Phe Leu Gln Phe Ser
                  20                  25                  30

 Lys Val Phe Leu Pro Cys Met Tyr Leu Val Val Phe Val Cys Gly
                  35                  40                  45

 Leu Val Gly Asn Ser Leu Val Leu Val Ile Ser Ile Phe Tyr His
                  50                  55                  60

 Lys Leu Gln Ser Leu Thr Asp Val Phe Leu Val Asn Leu Pro Leu
                  65                  70                  75

 Ala Asp Leu Val Phe Val Cys Thr Leu Pro Phe Trp Ala Tyr Ala
                  80                  85                  90

 Gly Ile His Glu Trp Val Phe Gly Gln Val Met Cys Lys Ser Leu
                  95                 100                 105

 Leu Gly Ile Tyr Thr Ile Asn Phe Tyr Thr Ser Met Leu Ile Leu
                 110                 115                 120

 Thr Cys Ile Thr Val Asp Arg Phe Ile Val Val Val Lys Ala Thr
                 125                 130                 135

 Lys Ala Tyr Asn Gln Gln Ala Lys Arg Met Thr Trp Gly Lys Val
                 140                 145                 150

 Thr Ser Leu Leu Ile Trp Val Ile Ser Leu Leu Val Ser Leu Pro
                 155                 160                 165

 Gln Ile Ile Tyr Gly Asn Val Phe Asn Leu Asp Lys Leu Ile Cys
                 170                 175                 180

 Gly Tyr His Asp Glu Ala Ile Ser Thr Val Val Leu Ala Thr Gln
                 185                 190                 195

 Met Thr Leu Gly Phe Phe Leu Pro Leu Leu Thr Met Ile Val Cys
                 200                 205                 210

 Tyr Ser Val Ile Ile Lys Thr Leu Leu His Ala Gly Gly Phe Gln
                 215                 220                 225

 Lys His Arg Ser Leu Lys Ile Ile Phe Leu Val Met Ala Val Phe
                 230                 235                 240

 Leu Leu Thr Gln Met Pro Phe Asn Leu Met Lys Phe Ile Arg Ser
                 245                 250                 255

 Thr His Trp Glu Tyr Tyr Ala Met Thr Ser Phe His Tyr Thr Ile
                 260                 265                 270

 Met Val Thr Glu Ala Ile Ala Tyr Leu Arg Ala Cys Leu Asn Pro
                 275                 280                 285

 Val Leu Tyr Ala Phe Val Ser Leu Lys Phe Arg Lys Asn Phe Trp
                 290                 295                 300

 Lys Leu Val Lys Asp Ile Gly Cys Leu Pro Tyr Leu Gly Val Ser
                 305                 310                 315

 His Gln Trp Lys Ser Ser Glu Asp Asn Ser Lys Thr Phe Ser Ala
                 320                 325                 330

 Ser His Asn Val Glu Ala Thr Ser Met Phe Gln Leu
                 335                 340

<210> 2385
<211> 3445
<212> DNA
<213> Homo sapien

<400> 2385
 gagtgactcc accgcccgga gcagcggtgc aggacgcgcg tctccgccgc 50

 ccgcggtgac ttctgcctgc gctccttctc tgaacgctca cttccgagga 100

 gacgccgacg atgaagacac cgtggaaggt tcttctggga ctgctgggtg 150

 ctgctgcgct tgtcaccatc atcaccgtgc ccgtggttct gctgaacaaa 200

 ggcacagatg atgctacagc tgacagtcgc aaaacttaca ctctaactga 250

 ttacttaaaa aatacttata gactgaagtt atactcctta agatggattt 300

 cagatcatga atatctctac aaacaagaaa ataatatctt ggtattcaat 350

 gctgaatatg gaaacagctc agttttcttg gagaacagta catttgatga 400

 gtttggacat tctatcaatg attattcaat atctcctgat gggcagttta 450

 ttctcttaga atacaactac gtgaagcaat ggaggcattc ctacacagct 500

 tcatatgaca tttatgattt aaataaaagg cagctgatta cagaagagag 550

 gattccaaac aacacacagt gggtcacatg gtcaccagtg ggtcataaat 600

 tggcatatgt ttggaacaat gacatttatg ttaaaattga accaaattta 650

 ccaagttaca gaatcacatg gacggggaaa gaagatataa tatataatgg 700

 aataactgac tgggtttatg aagaggaagt cttcagtgcc tactctgctc 750

 tgtggtggtc tccaaacggc acttttttag catatgccca atttaacgac 800

 acagaagtcc cacttattga atactccttc tactctgatg agtcactgca 850

 gtacccaaag actgtacggg ttccatatcc aaaggcagga gctgtgaatc 900

 caactgtaaa gttctttgtt gtaaatacag actctctcag ctcagtcacc 950

 aatgcaactt ccatacaaat cactgctcct gcttctatgt tgatagggga 1000

 tcactacttg tgtgatgtga catgggcaac acaagaaaga atttctttgc 1050

 agtggctcag gaggattcag aactattcgg tcatggatat ttgtgactat 1100

 gatgaatcca gtggaagatg gaactgctta gtggcacggc aacacattga 1150

 aatgagtact actggctggg ttggaagatt taggccttca gaacctcatt 1200

 ttacccttga tggtaatagc ttctacaaga tcatcagcaa tgaagaaggt 1250

 tacagacaca tttgctattt ccaaatagat aaaaaagact gcacatttat 1300

 tacaaaaggc acctgggaag tcatcgggat agaagctcta accagtgatt 1350

 atctatacta cattagtaat gaatataaag gaatgccagg aggaaggaat 1400

 ctttataaaa tccaacttag tgactataca aaagtgacat gcctcagttg 1450

 tgagctgaat ccggaaaggt gtcagtacta ttctgtgtca ttcagtaaag 1500

 aggcgaagta ttatcagctg agatgttccg gtcctggtct gcccctctat 1550

 actctacaca gcagcgtgaa tgataaaggg ctgagagtcc tggaagacaa 1600

 ttcagctttg gataaaatgc tgcagaatgt ccagatgccc tccaaaaaac 1650

 tggacttcat tattttgaat gaaacaaaat tttggtatca gatgatcttg 1700

 cctcctcatt ttgataaatc caagaaatat cctctactat tagatgtgta 1750

 tgcaggccca tgtagtcaaa aagcagacac tgtcttcaga ctgaactggg 1800

 ccacttacct tgcaagcaca gaaaacatta tagtagctag ctttgatggc 1850

 agaggaagtg gttaccaagg agataagatc atgcatgcaa tcaacagaag 1900

 actgggaaca tttgaagttg aagatcaaat tgaagcagcc agacaatttt 1950

 caaaaatggg atttgtggac aacaaacgaa ttgcaatttg gggctggtca 2000

 tatggagggt acgtaacctc aatggtcctg ggatcgggaa gtggcgtgtt 2050

 caagtgtgga atagccgtgg cgcctgtatc ccggtgggag tactatgact 2100

 cagtgtacac agaacgttac atgggtctcc caactccaga agacaacctt 2150

 gaccattaca gaaattcaac agtcatgagc agagctgaaa attttaaaca 2200

 agttgagtac ctccttattc atggaacagc agatgataac gttcactttc 2250

 agcagtcagc tcagatctcc aaagccctgg tcgatgttgg agtggatttc 2300

 caggcaatgt ggtatactga tgaagaccat ggaatagcta gcagcacagc 2350

 acaccaacat atatataccc acatgagcca cttcataaaa caatgtttct 2400

 ctttacctta gcacctcaaa ataccatgcc atttaaagct tattaaaact 2450

 catttttgtt ttcattatct caaaactgca ctgtcaagat gatgatgatc 2500

 tttaaaatac acactcaaat caagaaactt aaggttacct ttgttcccaa 2550

 atttcatacc tatcatctta agtagggact tctgtcttca caacagatta 2600

 ttaccttaca gaagtttgaa ttatccggtc gggttttatt gtttaaaatc 2650

 atttctgcat cagctgctga aacaacaaat aggaattgtt tttatggagg 2700

 ctttgcatag attccctgag caggatttta atctttttct aactggactg 2750

 gttcaaatgt tgttctcttc tttaaaggga tggcaagatg tgggcagtga 2800

 tgtcactagg gcagggacag gataagaggg attagggaga gaagatagca 2850

 gggcatggct gggaacccaa gtccaagcat accaacacga gcaggctact 2900

 gtcagctccc ctcggagaag agctgttcac agccagactg gcacagtttt 2950

 ctgagaaaga ctattcaaac agtctcagga aatcaaatat gcaaagcact 3000

 gacttctaag taaaaccaca gcagttgaaa agactccaaa gaaatgtaag 3050

 ggaaactgcc agcaacgcag gcccccaggt gccagttatg gctataggtg 3100

 ctacaaaaac acagcaaggg tgatgggaaa gcattgtaaa tgtgctttta 3150

 aaaaaaaata ctgatgttcc tagtgaaaga ggcagcttga aactgagatg 3200

 tgaacacatc agcttgccct gttaaaagat gaaaatattt gtatcacaaa 3250

 tcttaacttg aaggagtcct tgcatcaatt tttcttattt catttctttg 3300

 agtgtcttaa ttaaaagaat attttaactt ccttggactc attttaaaaa 3350

 atggaacata aaatacaatg ttatgtatta ttattcccat tctacatact 3400

 atggaatttc tcccagtcat ttaataaatg tgccttcatt ttttc 3445

<210> 2386
<211> 766
<212> PRT
<213> Homo sapien

<400> 2386
 Met Lys Thr Pro Trp Lys Val Leu Leu Gly Leu Leu Gly Ala Ala
   1               5                  10                  15

 Ala Leu Val Thr Ile Ile Thr Val Pro Val Val Leu Leu Asn Lys
                  20                  25                  30

 Gly Thr Asp Asp Ala Thr Ala Asp Ser Arg Lys Thr Tyr Thr Leu
                  35                  40                  45

 Thr Asp Tyr Leu Lys Asn Thr Tyr Arg Leu Lys Leu Tyr Ser Leu
                  50                  55                  60

 Arg Trp Ile Ser Asp His Glu Tyr Leu Tyr Lys Gln Glu Asn Asn
                  65                  70                  75

 Ile Leu Val Phe Asn Ala Glu Tyr Gly Asn Ser Ser Val Phe Leu
                  80                  85                  90

 Glu Asn Ser Thr Phe Asp Glu Phe Gly His Ser Ile Asn Asp Tyr
                  95                 100                 105

 Ser Ile Ser Pro Asp Gly Gln Phe Ile Leu Leu Glu Tyr Asn Tyr
                 110                 115                 120

 Val Lys Gln Trp Arg His Ser Tyr Thr Ala Ser Tyr Asp Ile Tyr
                 125                 130                 135

 Asp Leu Asn Lys Arg Gln Leu Ile Thr Glu Glu Arg Ile Pro Asn
                 140                 145                 150

 Asn Thr Gln Trp Val Thr Trp Ser Pro Val Gly His Lys Leu Ala
                 155                 160                 165

 Tyr Val Trp Asn Asn Asp Ile Tyr Val Lys Ile Glu Pro Asn Leu
                 170                 175                 180

 Pro Ser Tyr Arg Ile Thr Trp Thr Gly Lys Glu Asp Ile Ile Tyr
                 185                 190                 195

 Asn Gly Ile Thr Asp Trp Val Tyr Glu Glu Glu Val Phe Ser Ala
                 200                 205                 210

 Tyr Ser Ala Leu Trp Trp Ser Pro Asn Gly Thr Phe Leu Ala Tyr
                 215                 220                 225

 Ala Gln Phe Asn Asp Thr Glu Val Pro Leu Ile Glu Tyr Ser Phe
                 230                 235                 240

 Tyr Ser Asp Glu Ser Leu Gln Tyr Pro Lys Thr Val Arg Val Pro
                 245                 250                 255

 Tyr Pro Lys Ala Gly Ala Val Asn Pro Thr Val Lys Phe Phe Val
                 260                 265                 270

 Val Asn Thr Asp Ser Leu Ser Ser Val Thr Asn Ala Thr Ser Ile
                 275                 280                 285

 Gln Ile Thr Ala Pro Ala Ser Met Leu Ile Gly Asp His Tyr Leu
                 290                 295                 300

 Cys Asp Val Thr Trp Ala Thr Gln Glu Arg Ile Ser Leu Gln Trp
                 305                 310                 315

 Leu Arg Arg Ile Gln Asn Tyr Ser Val Met Asp Ile Cys Asp Tyr
                 320                 325                 330

 Asp Glu Ser Ser Gly Arg Trp Asn Cys Leu Val Ala Arg Gln His
                 335                 340                 345

 Ile Glu Met Ser Thr Thr Gly Trp Val Gly Arg Phe Arg Pro Ser
                 350                 355                 360

 Glu Pro His Phe Thr Leu Asp Gly Asn Ser Phe Tyr Lys Ile Ile
                 365                 370                 375

 Ser Asn Glu Glu Gly Tyr Arg His Ile Cys Tyr Phe Gln Ile Asp
                 380                 385                 390

 Lys Lys Asp Cys Thr Phe Ile Thr Lys Gly Thr Trp Glu Val Ile
                 395                 400                 405

 Gly Ile Glu Ala Leu Thr Ser Asp Tyr Leu Tyr Tyr Ile Ser Asn
                 410                 415                 420

 Glu Tyr Lys Gly Met Pro Gly Gly Arg Asn Leu Tyr Lys Ile Gln
                 425                 430                 435

 Leu Ser Asp Tyr Thr Lys Val Thr Cys Leu Ser Cys Glu Leu Asn
                 440                 445                 450

 Pro Glu Arg Cys Gln Tyr Tyr Ser Val Ser Phe Ser Lys Glu Ala
                 455                 460                 465

 Lys Tyr Tyr Gln Leu Arg Cys Ser Gly Pro Gly Leu Pro Leu Tyr
                 470                 475                 480

 Thr Leu His Ser Ser Val Asn Asp Lys Gly Leu Arg Val Leu Glu
                 485                 490                 495

 Asp Asn Ser Ala Leu Asp Lys Met Leu Gln Asn Val Gln Met Pro
                 500                 505                 510

 Ser Lys Lys Leu Asp Phe Ile Ile Leu Asn Glu Thr Lys Phe Trp
                 515                 520                 525

 Tyr Gln Met Ile Leu Pro Pro His Phe Asp Lys Ser Lys Lys Tyr
                 530                 535                 540

 Pro Leu Leu Leu Asp Val Tyr Ala Gly Pro Cys Ser Gln Lys Ala
                 545                 550                 555

 Asp Thr Val Phe Arg Leu Asn Trp Ala Thr Tyr Leu Ala Ser Thr
                 560                 565                 570

 Glu Asn Ile Ile Val Ala Ser Phe Asp Gly Arg Gly Ser Gly Tyr
                 575                 580                 585

 Gln Gly Asp Lys Ile Met His Ala Ile Asn Arg Arg Leu Gly Thr
                 590                 595                 600

 Phe Glu Val Glu Asp Gln Ile Glu Ala Ala Arg Gln Phe Ser Lys
                 605                 610                 615

 Met Gly Phe Val Asp Asn Lys Arg Ile Ala Ile Trp Gly Trp Ser
                 620                 625                 630

 Tyr Gly Gly Tyr Val Thr Ser Met Val Leu Gly Ser Gly Ser Gly
                 635                 640                 645

 Val Phe Lys Cys Gly Ile Ala Val Ala Pro Val Ser Arg Trp Glu
                 650                 655                 660

 Tyr Tyr Asp Ser Val Tyr Thr Glu Arg Tyr Met Gly Leu Pro Thr
                 665                 670                 675

 Pro Glu Asp Asn Leu Asp His Tyr Arg Asn Ser Thr Val Met Ser
                 680                 685                 690

 Arg Ala Glu Asn Phe Lys Gln Val Glu Tyr Leu Leu Ile His Gly
                 695                 700                 705

 Thr Ala Asp Asp Asn Val His Phe Gln Gln Ser Ala Gln Ile Ser
                 710                 715                 720

 Lys Ala Leu Val Asp Val Gly Val Asp Phe Gln Ala Met Trp Tyr
                 725                 730                 735

 Thr Asp Glu Asp His Gly Ile Ala Ser Ser Thr Ala His Gln His
                 740                 745                 750

 Ile Tyr Thr His Met Ser His Phe Ile Lys Gln Cys Phe Ser Leu
                 755                 760                 765

 Pro


<210> 2387
<211> 2862
<212> DNA
<213> Homo sapien

<400> 2387
 cggagccctg cgagtaggca gcgttgggcc catgcaggac gcggagaacg 50

 tggcggtgcc cgaggcggcc gaggagcgcg ccgagcccgg ccagcagcag 100

 ccggccgccg agccgccgcc agccgagggg ctgctgcggc ccgcggggcc 150

 cggcgctccg gaggccgcgg ggaccgaggc ctccagtgag gaggtgggga 200

 tcgcggaggc cgggccggag cccgaggtga ggaccgagcc ggcggccgag 250

 gcagaggcgg cctccggccc gtccgagtcg ccctcgccgc cggccgccga 300

 ggagctgccc gggtcgcatg ctgagccccc tgtcccggca cagggcgagg 350

 ccccaggaga gcaggctcgg gacgagcgct ccgacagccg ggcccaggcg 400

 gtgtccgagg acgcgggagg aaacgagggc agagcggccg aggccgaacc 450

 ccgggcgctg gagaatggcg acgcggacga gccctccttc agcgaccccg 500

 aggacttcgt ggacgacgtg agcgaggaag aattactggg agatgtactc 550

 aaagatcggc cccaggaagc agatggaatc gattcggtga ttgtagtgga 600

 caatgtccct caggtgggac ccgaccgact tgagaaactc aaaaatgtca 650

 tccacaagat cttttccaag tttgggaaaa tcacaaatga tttttatcct 700

 gaagaggatg ggaagacaaa agggtatatt ttcctggagt acgcgtcccc 750

 tgcccacgct gtggatgctg tgaagaacgc cgacggctac aagcttgaca 800

 agcagcacac attccgggtc aacctcttta cggattttga caagtatatg 850

 acgatcagtg acgagtggga tattccagag aaacagcctt tcaaagacct 900

 ggggaactta cgttactggc ttgaagaggc agaatgcaga gatcagtaca 950

 gtgtgatttt tgagagtgga gaccgcactt ccatattctg gaatgacgta 1000

 aaagaccctg tctcaattga agaaagagcg agatggacag agacgtatgt 1050

 gcgttggtct cctaagggca cctacctggc tacctttcat caaagaggca 1100

 ttgctctatg ggggggagag aaattcaagc aaattcagag attcagccac 1150

 caaggggttc agcttattga cttctcacct tgtgaaaggt acctggtgac 1200

 ctttagcccc ctgatggaca cgcaggatga ccctcaggcc ataatcatct 1250

 gggacatcct tacggggcac aagaagaggg gttttcactg tgagagctca 1300

 gcccattggc ctatttttaa gtggagccat gatggcaaat tctttgccag 1350

 aatgaccctg gatacgctta gcatctatga aactccttct atgggtcttt 1400

 tggacaagaa gagtttgaag atctctggga taaaagactt ttcttggtct 1450

 cctggtggta acataatcgc cttctgggtg cctgaagaca aagatattcc 1500

 agccagggta accctgatgc agctccctac caggcaagag atccgagtga 1550

 ggaacctgtt caatgtggtg gactgcaagc tccattggca gaagaacgga 1600

 gactacttgt gtgtgaaagt agataggact ccgaaaggca cccagggtgt 1650

 tgtcacaaat tttgaaattt tccgaatgag ggagaaacag gtacctgtgg 1700

 atgtggtcga gatgaaagaa accatcatag cctttgcctg ggaaccaaat 1750

 ggaagtaagt ttgctgtgct gcacggagag gctccgcgga tatctgtgtc 1800

 tttctaccac gtcaaaaaca acgggaagat tgaactcatc aagatgttcg 1850

 acaagcagca ggcgaacacc atcttctgga gcccccaagg acagttcgtg 1900

 gtgttggcgg gcctgaggag tatgaacggt gccttagcgt ttgtggacac 1950

 ttcggactgc acggtcatga acatcgcaga gcactacatg gcttccgacg 2000

 tcgaatggga tcctactggg cgctacgtcg tcacctctgt gtcctggtgg 2050

 agccataagg tggacaacgc gtactggctg tggactttcc agggacgcct 2100

 cctgcagaag aacaacaagg accgcttctg ccagctgctg tggcggcccc 2150

 ggcctcccac actcctgagc caggaacaga tcaagcaaat taaaaaggat 2200

 ctgaagaaat actctaagat ctttgaacag aaggatcgtt tgagtcagtc 2250

 caaagcctca aaggaattgg tggagagaag gcgcaccatg atggaagatt 2300

 tccggaagta ccggaaaatg gcccaggagc tctatatgga gcagaaaaac 2350

 gagcgcctgg agttgcgagg aggggtggac actgacgagc tggacagcaa 2400

 cgtggacgac tgggaagagg agaccattga gttcttcgtc actgaagaaa 2450

 tcattcccct cgggaatcag gagtgacctg gagcactgtg cgcagccgtg 2500

 tgtgctgtgg agccgaggcc gtcctgcagg aagccgcgtg actcccgcct 2550

 cctccctgtg ctctctggct ctggactgtg actgcgcctg gattctgcca 2600

 ttgcgacact tagcgacgcc actggcggca ccttctcctg cgcccagtga 2650

 tgtttccacg gtgcctgtac acagccgagc agcatttccg ttgaaggact 2700

 tgcatcccca ttgcgggcag tgctggacgt gtcccggaga cccaccggga 2750

 gggcgccgcc atgccttgta cccccaccgt gcaggttgtg gccggttttc 2800

 tccgcaggtt gaacatggaa ataaaagcaa acttgtatga aaaaaaaaaa 2850

 aaaaaaaaaa aa 2862

<210> 2388
<211> 814
<212> PRT
<213> Homo sapien

<400> 2388
 Met Gln Asp Ala Glu Asn Val Ala Val Pro Glu Ala Ala Glu Glu
   1               5                  10                  15

 Arg Ala Glu Pro Gly Gln Gln Gln Pro Ala Ala Glu Pro Pro Pro
                  20                  25                  30

 Ala Glu Gly Leu Leu Arg Pro Ala Gly Pro Gly Ala Pro Glu Ala
                  35                  40                  45

 Ala Gly Thr Glu Ala Ser Ser Glu Glu Val Gly Ile Ala Glu Ala
                  50                  55                  60

 Gly Pro Glu Pro Glu Val Arg Thr Glu Pro Ala Ala Glu Ala Glu
                  65                  70                  75

 Ala Ala Ser Gly Pro Ser Glu Ser Pro Ser Pro Pro Ala Ala Glu
                  80                  85                  90

 Glu Leu Pro Gly Ser His Ala Glu Pro Pro Val Pro Ala Gln Gly
                  95                 100                 105

 Glu Ala Pro Gly Glu Gln Ala Arg Asp Glu Arg Ser Asp Ser Arg
                 110                 115                 120

 Ala Gln Ala Val Ser Glu Asp Ala Gly Gly Asn Glu Gly Arg Ala
                 125                 130                 135

 Ala Glu Ala Glu Pro Arg Ala Leu Glu Asn Gly Asp Ala Asp Glu
                 140                 145                 150

 Pro Ser Phe Ser Asp Pro Glu Asp Phe Val Asp Asp Val Ser Glu
                 155                 160                 165

 Glu Glu Leu Leu Gly Asp Val Leu Lys Asp Arg Pro Gln Glu Ala
                 170                 175                 180

 Asp Gly Ile Asp Ser Val Ile Val Val Asp Asn Val Pro Gln Val
                 185                 190                 195

 Gly Pro Asp Arg Leu Glu Lys Leu Lys Asn Val Ile His Lys Ile
                 200                 205                 210

 Phe Ser Lys Phe Gly Lys Ile Thr Asn Asp Phe Tyr Pro Glu Glu
                 215                 220                 225

 Asp Gly Lys Thr Lys Gly Tyr Ile Phe Leu Glu Tyr Ala Ser Pro
                 230                 235                 240

 Ala His Ala Val Asp Ala Val Lys Asn Ala Asp Gly Tyr Lys Leu
                 245                 250                 255

 Asp Lys Gln His Thr Phe Arg Val Asn Leu Phe Thr Asp Phe Asp
                 260                 265                 270

 Lys Tyr Met Thr Ile Ser Asp Glu Trp Asp Ile Pro Glu Lys Gln
                 275                 280                 285

 Pro Phe Lys Asp Leu Gly Asn Leu Arg Tyr Trp Leu Glu Glu Ala
                 290                 295                 300

 Glu Cys Arg Asp Gln Tyr Ser Val Ile Phe Glu Ser Gly Asp Arg
                 305                 310                 315

 Thr Ser Ile Phe Trp Asn Asp Val Lys Asp Pro Val Ser Ile Glu
                 320                 325                 330

 Glu Arg Ala Arg Trp Thr Glu Thr Tyr Val Arg Trp Ser Pro Lys
                 335                 340                 345

 Gly Thr Tyr Leu Ala Thr Phe His Gln Arg Gly Ile Ala Leu Trp
                 350                 355                 360

 Gly Gly Glu Lys Phe Lys Gln Ile Gln Arg Phe Ser His Gln Gly
                 365                 370                 375

 Val Gln Leu Ile Asp Phe Ser Pro Cys Glu Arg Tyr Leu Val Thr
                 380                 385                 390

 Phe Ser Pro Leu Met Asp Thr Gln Asp Asp Pro Gln Ala Ile Ile
                 395                 400                 405

 Ile Trp Asp Ile Leu Thr Gly His Lys Lys Arg Gly Phe His Cys
                 410                 415                 420

 Glu Ser Ser Ala His Trp Pro Ile Phe Lys Trp Ser His Asp Gly
                 425                 430                 435

 Lys Phe Phe Ala Arg Met Thr Leu Asp Thr Leu Ser Ile Tyr Glu
                 440                 445                 450

 Thr Pro Ser Met Gly Leu Leu Asp Lys Lys Ser Leu Lys Ile Ser
                 455                 460                 465

 Gly Ile Lys Asp Phe Ser Trp Ser Pro Gly Gly Asn Ile Ile Ala
                 470                 475                 480

 Phe Trp Val Pro Glu Asp Lys Asp Ile Pro Ala Arg Val Thr Leu
                 485                 490                 495

 Met Gln Leu Pro Thr Arg Gln Glu Ile Arg Val Arg Asn Leu Phe
                 500                 505                 510

 Asn Val Val Asp Cys Lys Leu His Trp Gln Lys Asn Gly Asp Tyr
                 515                 520                 525

 Leu Cys Val Lys Val Asp Arg Thr Pro Lys Gly Thr Gln Gly Val
                 530                 535                 540

 Val Thr Asn Phe Glu Ile Phe Arg Met Arg Glu Lys Gln Val Pro
                 545                 550                 555

 Val Asp Val Val Glu Met Lys Glu Thr Ile Ile Ala Phe Ala Trp
                 560                 565                 570

 Glu Pro Asn Gly Ser Lys Phe Ala Val Leu His Gly Glu Ala Pro
                 575                 580                 585

 Arg Ile Ser Val Ser Phe Tyr His Val Lys Asn Asn Gly Lys Ile
                 590                 595                 600

 Glu Leu Ile Lys Met Phe Asp Lys Gln Gln Ala Asn Thr Ile Phe
                 605                 610                 615

 Trp Ser Pro Gln Gly Gln Phe Val Val Leu Ala Gly Leu Arg Ser
                 620                 625                 630

 Met Asn Gly Ala Leu Ala Phe Val Asp Thr Ser Asp Cys Thr Val
                 635                 640                 645

 Met Asn Ile Ala Glu His Tyr Met Ala Ser Asp Val Glu Trp Asp
                 650                 655                 660

 Pro Thr Gly Arg Tyr Val Val Thr Ser Val Ser Trp Trp Ser His
                 665                 670                 675

 Lys Val Asp Asn Ala Tyr Trp Leu Trp Thr Phe Gln Gly Arg Leu
                 680                 685                 690

 Leu Gln Lys Asn Asn Lys Asp Arg Phe Cys Gln Leu Leu Trp Arg
                 695                 700                 705

 Pro Arg Pro Pro Thr Leu Leu Ser Gln Glu Gln Ile Lys Gln Ile
                 710                 715                 720

 Lys Lys Asp Leu Lys Lys Tyr Ser Lys Ile Phe Glu Gln Lys Asp
                 725                 730                 735

 Arg Leu Ser Gln Ser Lys Ala Ser Lys Glu Leu Val Glu Arg Arg
                 740                 745                 750

 Arg Thr Met Met Glu Asp Phe Arg Lys Tyr Arg Lys Met Ala Gln
                 755                 760                 765

 Glu Leu Tyr Met Glu Gln Lys Asn Glu Arg Leu Glu Leu Arg Gly
                 770                 775                 780

 Gly Val Asp Thr Asp Glu Leu Asp Ser Asn Val Asp Asp Trp Glu
                 785                 790                 795

 Glu Glu Thr Ile Glu Phe Phe Val Thr Glu Glu Ile Ile Pro Leu
                 800                 805                 810

 Gly Asn Gln Glu


<210> 2389
<211> 1723
<212> DNA
<213> Homo sapien

<400> 2389
 tcgcggaggc ttggggcagc cgggtagctc ggaggtcgtg gcgctggggg 50

 ctagcaccag cgctctgtcg ggaggcgcag cggttaggtg gaccggtcag 100

 cggactcacc ggccagggcg ctcggtgctg gaatttgata ttcattgatc 150

 cgggttttat ccctcttctt ttttcttaaa catttttttt taaaactgta 200

 ttgtttctcg ttttaattta tttttgcttg ccattcccca cttgaatcgg 250

 gccgacggct tggggagatt gctctacttc cccaaatcac tgtggatttt 300

 ggaaaccagc agaaagagga aagaggtagc aagagctcca gagagaagtc 350

 gaggaagaga gagacggggt cagagagagc gcgcgggcgt gcgagcagcg 400

 aaagcgacag gggcaaagtg agtgacctgc ttttgggggt gaccgccgga 450

 gcgcggcgtg agccctcccc cttgggatcc cgcagctgac cagtcgcgct 500

 gacggacaga cagacagaca ccgcccccag ccccagctac cacctcctcc 550

 ccggccggcg gcggacagtg gacgcggcgg cgagccgcgg gcaggggccg 600

 gagcccgcgc ccggaggcgg ggtggagggg gtcggggctc gcggcgtcgc 650

 actgaaactt ttcgtccaac ttctgggctg ttctcgcttc ggaggagccg 700

 tggtccgcgc gggggaagcc gagccgagcg gagccgcgag aagtgctagc 750

 tcgggccggg aggagccgca gccggaggag ggggaggagg aagaagagaa 800

 ggaagaggag agggggccgc agtggcgact cggcgctcgg aagccgggct 850

 catggacggg tgaggcggcg gtgtgcgcag acagtgctcc agccgcgcgc 900

 gctccccagg ccctggcccg ggcctcgggc cggggaggaa gagtagctcg 950

 ccgaggcgcc gaggagagcg ggccgcccca cagcccgagc cggagaggga 1000

 gcgcgagccg cgccggcccc ggtcgggcct ccgaaaccat gaactttctg 1050

 ctgtcttggg tgcattggag ccttgccttg ctgctctacc tccaccatgc 1100

 caagtggtcc caggctgcac ccatggcaga aggaggaggg cagaatcatc 1150

 acgaagtggt gaagttcatg gatgtctatc agcgcagcta ctgccatcca 1200

 atcgagaccc tggtggacat cttccaggag taccctgatg agatcgagta 1250

 catcttcaag ccatcctgtg tgcccctgat gcgatgcggg ggctgctgca 1300

 atgacgaggg cctggagtgt gtgcccactg aggagtccaa catcaccatg 1350

 cagattatgc ggatcaaacc tcaccaaggc cagcacatag gagagatgag 1400

 cttcctacag cacaacaaat gtgaatgcag accaaagaaa gatagagcaa 1450

 gacaagaaaa aaaatcagtt cgaggaaagg gaaaggggca aaaacgaaag 1500

 cgcaagaaat cccggtataa gtcctggagc gttccctgtg ggccttgctc 1550

 agagcggaga aagcatttgt ttgtacaaga tccgcagacg tgtaaatgtt 1600

 cctgcaaaaa cacagactcg cgttgcaagg cgaggcagct tgagttaaac 1650

 gaacgtactt gcagatgtga caagccgagg cggtgagccg ggcaggagga 1700

 aggagcctcc ctcagggttt cgg 1723

<210> 2390
<211> 215
<212> PRT
<213> Homo sapien

<400> 2390
 Met Asn Phe Leu Leu Ser Trp Val His Trp Ser Leu Ala Leu Leu
   1               5                  10                  15

 Leu Tyr Leu His His Ala Lys Trp Ser Gln Ala Ala Pro Met Ala
                  20                  25                  30

 Glu Gly Gly Gly Gln Asn His His Glu Val Val Lys Phe Met Asp
                  35                  40                  45

 Val Tyr Gln Arg Ser Tyr Cys His Pro Ile Glu Thr Leu Val Asp
                  50                  55                  60

 Ile Phe Gln Glu Tyr Pro Asp Glu Ile Glu Tyr Ile Phe Lys Pro
                  65                  70                  75

 Ser Cys Val Pro Leu Met Arg Cys Gly Gly Cys Cys Asn Asp Glu
                  80                  85                  90

 Gly Leu Glu Cys Val Pro Thr Glu Glu Ser Asn Ile Thr Met Gln
                  95                 100                 105

 Ile Met Arg Ile Lys Pro His Gln Gly Gln His Ile Gly Glu Met
                 110                 115                 120

 Ser Phe Leu Gln His Asn Lys Cys Glu Cys Arg Pro Lys Lys Asp
                 125                 130                 135

 Arg Ala Arg Gln Glu Lys Lys Ser Val Arg Gly Lys Gly Lys Gly
                 140                 145                 150

 Gln Lys Arg Lys Arg Lys Lys Ser Arg Tyr Lys Ser Trp Ser Val
                 155                 160                 165

 Pro Cys Gly Pro Cys Ser Glu Arg Arg Lys His Leu Phe Val Gln
                 170                 175                 180

 Asp Pro Gln Thr Cys Lys Cys Ser Cys Lys Asn Thr Asp Ser Arg
                 185                 190                 195

 Cys Lys Ala Arg Gln Leu Glu Leu Asn Glu Arg Thr Cys Arg Cys
                 200                 205                 210

 Asp Lys Pro Arg Arg
                 215

<210> 2391
<211> 598
<212> DNA
<213> Homo sapien

<400> 2391
 ctccttcttt tccagccccg gtaccggacc ctgcagccgc agagatgttg 50

 atgcctaaga agaaccggat tgccatttat gaactccttt ttaaggaggg 100

 agtcatggtg gccaagaagg atgtccacat gcctaagcac ccggagctgg 150

 cagacaagaa tgtgcccaac cttcatgtca tgaaggccat gcagtctctc 200

 aagtcccgag gctacgtgaa ggaacagttt gcctggagac atttctactg 250

 gtaccttacc aatgagggta tccagtatct ccgtgattac cttcatctgc 300

 ccccggagat tgtgcctgcc accctacgcc gtagccgtcc agagactggc 350

 aggcctcggc ctaaaggtct ggagggtgag cgacctgcga gactcacaag 400

 aggggaagct gacagagata cctacagacg gagtgctgtg ccacctggtg 450

 ccgacaagaa agccgaggct ggggctgggt cagcaaccga attccagttt 500

 agaggcggat ttggtcgtgg acgtggtcag ccacctcagt aaaattggag 550

 aggattcttt tgcattgaat aaacttacag ccaaaaaacc ttaaaaaa 598

<210> 2392
<211> 165
<212> PRT
<213> Homo sapien

<400> 2392
 Met Leu Met Pro Lys Lys Asn Arg Ile Ala Ile Tyr Glu Leu Leu
   1               5                  10                  15

 Phe Lys Glu Gly Val Met Val Ala Lys Lys Asp Val His Met Pro
                  20                  25                  30

 Lys His Pro Glu Leu Ala Asp Lys Asn Val Pro Asn Leu His Val
                  35                  40                  45

 Met Lys Ala Met Gln Ser Leu Lys Ser Arg Gly Tyr Val Lys Glu
                  50                  55                  60

 Gln Phe Ala Trp Arg His Phe Tyr Trp Tyr Leu Thr Asn Glu Gly
                  65                  70                  75

 Ile Gln Tyr Leu Arg Asp Tyr Leu His Leu Pro Pro Glu Ile Val
                  80                  85                  90

 Pro Ala Thr Leu Arg Arg Ser Arg Pro Glu Thr Gly Arg Pro Arg
                  95                 100                 105

 Pro Lys Gly Leu Glu Gly Glu Arg Pro Ala Arg Leu Thr Arg Gly
                 110                 115                 120

 Glu Ala Asp Arg Asp Thr Tyr Arg Arg Ser Ala Val Pro Pro Gly
                 125                 130                 135

 Ala Asp Lys Lys Ala Glu Ala Gly Ala Gly Ser Ala Thr Glu Phe
                 140                 145                 150

 Gln Phe Arg Gly Gly Phe Gly Arg Gly Arg Gly Gln Pro Pro Gln
                 155                 160                 165

<210> 2393
<211> 2848
<212> DNA
<213> Homo sapien

<400> 2393
 cgcggcactc gcgcgcgatc ccggccggcg gcgcgccggc gggccaggcg 50

 gcgccacagc ccatggagct cgagaacatc gtagcgaaca cggtgctact 100

 caaggcccgg gaaggtggcg gtggaaatcg caaaggcaaa agcaagaaat 150

 ggcggcagat gctccagttc cctcacatca gccagtgcga agagctgcgg 200

 ctcagcctcg agcgtgacta tcacagcctg tgcgagcggc acgccattgg 250

 gcgcctgctg ttccgagagt tctgtgccac gaggccggag ctgagccgct 300

 gcgtcgcctt cctggatggg gtggccgagt atgaagtgac cccggatgac 350

 aagcggaagg catgtgggcg gcacgtaacg cagaattttc tgagccacac 400

 gggtcctgac ctcatccctg aggtcccccg gcagctggtg acgaactgca 450

 cccagcggct ggagcagggt ccctgcaaag accttttcca ggaactcacc 500

 cggctgaccc acgagtacct gagcgtggcc ccttttgccg actacctcga 550

 cagcatctac ttcaaccgtt tcctgcagtg gaagtggctg gaaaggcagc 600

 cagtgaccaa aaacaccttc aggcaatacc gagtcctggg caaaggtggc 650

 tttggggagg tgtgcgcctg ccaggtgcgg gccacaggta agatgtatgc 700

 ctgcaagaag ctagagaaaa agcggatcaa gaagcggaaa ggggaggcca 750

 tggcgctgaa cgagaagcag atcctggaga aagtgaacag taggtttgta 800

 gtgagcttgg cctacgccta tgagaccaag gacgcgctgt gcctggtgct 850

 gacactgatg aacgggggcg acctcaagtt ccacatctac cacatgggcc 900

 aggctggctt ccccgaagcg cgggccgtct tctacgccgc cgagatctgc 950

 tgtggcctgg aggacctgca ccgggagcgc atcgtgtaca gggacctgaa 1000

 gcccgagaac atcttgctgg atgaccacgg ccacatccgc atctctgacc 1050

 tgggactagc tgtgcatgtg cccgagggcc agaccatcaa agggcgtgtg 1100

 ggcaccgtgg gttacatggc tccggaggtg gtgaagaatg aacggtacac 1150

 gttcagccct gactggtggg cgctcggctg cctcctgtac gagatgatcg 1200

 caggccagtc gcccttccag cagaggaaga agaagatcaa gcgggaggag 1250

 gtggagcggc tggtgaagga ggtccccgag gagtattccg agcgcttttc 1300

 cccgcaggcc cgctcacttt gctcacagct cctctgcaag gaccctgccg 1350

 aacgcctggg gtgtcgtggg ggcagtgccc gcgaggtgaa ggagcacccc 1400

 ctctttaaga agctgaactt caagcggctg ggagctggca tgctggagcc 1450

 gccgttcaag cctgaccccc aggccattta ctgcaaggat gttctggaca 1500

 ttgaacagtt ctctacggtc aagggcgtgg agctggagcc taccgaccag 1550

 gacttctacc agaagtttgc cacaggcagt gtgcccatcc cctggcagaa 1600

 cgagatggtg gagaccgagt gcttccaaga gctgaatgtc tttgggctgg 1650

 atggctcagt tcccccagac ctggactgga agggccagcc acctgcacct 1700

 cctaaaaagg gactgctgca gagactcttc agtcgccaag attgctgtgg 1750

 aaactgcagc gacagcgagg aagagctccc cacccgcctc tagcccccag 1800

 cccgaggccc ccaccagcag ttggcggtag cagctactcc gagcgccgtt 1850

 tacagttttg cacagtgatc ttccccattg tccactcaag tcgtggcctg 1900

 gggaacacag acggagctgt ccccagtgtc ctccgtccct cagcccctgg 1950

 cctggctgag tttggcaggg cctgggccat ccctgggaca aaggtgcgtc 2000

 ccttcagctc ttctccgtgg agctcggggc tttctgtatt tatgtatttg 2050

 tacgaatgta tatagcgacc agagcattct taattcccgc cgcagacctg 2100

 gcgcccccgc cttggctcct gggggcagcc agccctggct ggagagcggg 2150

 acgtggcaga ggagccactg ccaaactcaa ggctcctctg gcccagcttg 2200

 gatggctgag ggtggtcaca cctgagcctt cagcactgtg ctgccacccc 2250

 ggcctctgag taagactcgt gcctccccct gctgccctgg gctcaggctg 2300

 ctacctctgg ggcccaaagc tgtcccttct cagtgcttgt cagcgctggg 2350

 tctggggcct ctgtatgccc taggcctgtg ccaaagtggc cagagattgg 2400

 gctgcctgtg atacccatca gcccactgcc ccggccggcc cagataggtc 2450

 tgcctctgcc ttccagctcc cacagcctgg tccctgatac tgggctctgt 2500

 cctgcagaca cctctttcag aaacgcccaa gcccagccct aggagggggt 2550

 ggggcatccc tggtcaaccc tcaaacattc cggactcccc tcataacaat 2600

 agacacatgt gcccagcaat aatccgcccc ttcctgtgtg cgcctgtggg 2650

 gtgcgtgctc tctgtgtgta cctgtgtggg tgaaggggat agggcgaggc 2700

 tgtgcctgtg ccccaggtcc cagccctggc ccttcccaga ctgtgatggc 2750

 catcctggtc ccagtgttag ggtagcatgg gattacaggg ccctgttttt 2800

 tccatattta aagccaattt ttattactcg ttttgtccaa cgtaaaag 2848

<210> 2394
<211> 576
<212> PRT
<213> Homo sapien

<400> 2394
 Met Glu Leu Glu Asn Ile Val Ala Asn Thr Val Leu Leu Lys Ala
   1               5                  10                  15

 Arg Glu Gly Gly Gly Gly Asn Arg Lys Gly Lys Ser Lys Lys Trp
                  20                  25                  30

 Arg Gln Met Leu Gln Phe Pro His Ile Ser Gln Cys Glu Glu Leu
                  35                  40                  45

 Arg Leu Ser Leu Glu Arg Asp Tyr His Ser Leu Cys Glu Arg His
                  50                  55                  60

 Ala Ile Gly Arg Leu Leu Phe Arg Glu Phe Cys Ala Thr Arg Pro
                  65                  70                  75

 Glu Leu Ser Arg Cys Val Ala Phe Leu Asp Gly Val Ala Glu Tyr
                  80                  85                  90

 Glu Val Thr Pro Asp Asp Lys Arg Lys Ala Cys Gly Arg His Val
                  95                 100                 105

 Thr Gln Asn Phe Leu Ser His Thr Gly Pro Asp Leu Ile Pro Glu
                 110                 115                 120

 Val Pro Arg Gln Leu Val Thr Asn Cys Thr Gln Arg Leu Glu Gln
                 125                 130                 135

 Gly Pro Cys Lys Asp Leu Phe Gln Glu Leu Thr Arg Leu Thr His
                 140                 145                 150

 Glu Tyr Leu Ser Val Ala Pro Phe Ala Asp Tyr Leu Asp Ser Ile
                 155                 160                 165

 Tyr Phe Asn Arg Phe Leu Gln Trp Lys Trp Leu Glu Arg Gln Pro
                 170                 175                 180

 Val Thr Lys Asn Thr Phe Arg Gln Tyr Arg Val Leu Gly Lys Gly
                 185                 190                 195

 Gly Phe Gly Glu Val Cys Ala Cys Gln Val Arg Ala Thr Gly Lys
                 200                 205                 210

 Met Tyr Ala Cys Lys Lys Leu Glu Lys Lys Arg Ile Lys Lys Arg
                 215                 220                 225

 Lys Gly Glu Ala Met Ala Leu Asn Glu Lys Gln Ile Leu Glu Lys
                 230                 235                 240

 Val Asn Ser Arg Phe Val Val Ser Leu Ala Tyr Ala Tyr Glu Thr
                 245                 250                 255

 Lys Asp Ala Leu Cys Leu Val Leu Thr Leu Met Asn Gly Gly Asp
                 260                 265                 270

 Leu Lys Phe His Ile Tyr His Met Gly Gln Ala Gly Phe Pro Glu
                 275                 280                 285

 Ala Arg Ala Val Phe Tyr Ala Ala Glu Ile Cys Cys Gly Leu Glu
                 290                 295                 300

 Asp Leu His Arg Glu Arg Ile Val Tyr Arg Asp Leu Lys Pro Glu
                 305                 310                 315

 Asn Ile Leu Leu Asp Asp His Gly His Ile Arg Ile Ser Asp Leu
                 320                 325                 330

 Gly Leu Ala Val His Val Pro Glu Gly Gln Thr Ile Lys Gly Arg
                 335                 340                 345

 Val Gly Thr Val Gly Tyr Met Ala Pro Glu Val Val Lys Asn Glu
                 350                 355                 360

 Arg Tyr Thr Phe Ser Pro Asp Trp Trp Ala Leu Gly Cys Leu Leu
                 365                 370                 375

 Tyr Glu Met Ile Ala Gly Gln Ser Pro Phe Gln Gln Arg Lys Lys
                 380                 385                 390

 Lys Ile Lys Arg Glu Glu Val Glu Arg Leu Val Lys Glu Val Pro
                 395                 400                 405

 Glu Glu Tyr Ser Glu Arg Phe Ser Pro Gln Ala Arg Ser Leu Cys
                 410                 415                 420

 Ser Gln Leu Leu Cys Lys Asp Pro Ala Glu Arg Leu Gly Cys Arg
                 425                 430                 435

 Gly Gly Ser Ala Arg Glu Val Lys Glu His Pro Leu Phe Lys Lys
                 440                 445                 450

 Leu Asn Phe Lys Arg Leu Gly Ala Gly Met Leu Glu Pro Pro Phe
                 455                 460                 465

 Lys Pro Asp Pro Gln Ala Ile Tyr Cys Lys Asp Val Leu Asp Ile
                 470                 475                 480

 Glu Gln Phe Ser Thr Val Lys Gly Val Glu Leu Glu Pro Thr Asp
                 485                 490                 495

 Gln Asp Phe Tyr Gln Lys Phe Ala Thr Gly Ser Val Pro Ile Pro
                 500                 505                 510

 Trp Gln Asn Glu Met Val Glu Thr Glu Cys Phe Gln Glu Leu Asn
                 515                 520                 525

 Val Phe Gly Leu Asp Gly Ser Val Pro Pro Asp Leu Asp Trp Lys
                 530                 535                 540

 Gly Gln Pro Pro Ala Pro Pro Lys Lys Gly Leu Leu Gln Arg Leu
                 545                 550                 555

 Phe Ser Arg Gln Asp Cys Cys Gly Asn Cys Ser Asp Ser Glu Glu
                 560                 565                 570

 Glu Leu Pro Thr Arg Leu
                 575

<210> 2395
<211> 2044
<212> DNA
<213> Homo sapien

<400> 2395
 ccggtcggat gccggaccgg gggcaccgct gaggcggtgg gtccccgacc 50

 tgcgagacag gtttggaagc ccccgctgcg cccagtccgt gcggaccgcg 100

 aggccgcggg cgggtggagg cgcgtctccg gcacgatgaa ggatttgggg 150

 gcagagcact tggcaggtca tgaaggggtc caacttctcg ggttgttgaa 200

 cgtctacctg gaacaagaag agagattcca acctcgagaa aaagggctga 250

 gtttgattga ggctaccccg gagaatgata acactttgtg tccaggattg 300

 agaaatgcca aagttgaaga tttaaggagt ttagccaact tttttggatc 350

 ttgcactgaa acttttgtcc tggctgtcaa tattttggac aggttcttgg 400

 ctcttatgaa ggtgaaacct aaacatttgt cttgcattgg agtctgttct 450

 tttttgctgg ctgctagaat agttgaagaa gactgcaata ttccatccac 500

 tcatgatgtg atccggatta gtcagtgtaa atgtactgct tctgacataa 550

 aacggatgga aaaaataatt tcagaaaaat tgcactatga attggaagct 600

 actactgcct taaacttttt gcacttatac catactatta tactttgtca 650

 tacttcagaa aggaaagaaa tactgagcct tgataaacta gaagctcagc 700

 tgaaagcttg caactgccga ctcatctttt caaaagcaaa accatctgta 750

 ttagccttgt gccttctcaa tttggaagtg gaaactttga aatctgttga 800

 attactggaa attctcttgc tagttaaaaa acattccaag attaatgaca 850

 ctgagttctt ctactggaga gagttggttt ctaaatgcct agccgagtat 900

 tcttctcctg aatgttgcaa accagatctt aagaagttgg tttggatcgt 950

 ttcaaggcgc acagcccaga acctccacaa cagctactat agtgttcctg 1000

 agctgccaac gatacctgag gggggttgtt ttgatgaaag tgaaagtgag 1050

 gactcttgtg aagatatgag ttgtggagag gagagtctca gcagctctcc 1100

 tcccagtgat caagagtgca ccttcttttt caacttcaaa gtggcacaaa 1150

 cactgtgctt tccatcttag aaatctgatt gttctgtcag aatttatatt 1200

 tacagggttt caaagcaata aatgggggaa taggtagttt cctggtttag 1250

 cccccatcta gtcaggaatt aatatactgg aatacctacc ttctatttgt 1300

 tattcagatc agatctggcc tattttcata tttatcctaa gccatcaaat 1350

 ggggtagtgc ctcttaaacc attaacagta ctttagacat tggcacttta 1400

 tttttctcgt agatctttag ctactttggg gaggagggaa ggtgctgata 1450

 ccttcaattt gttacttttc aagattttta aaaataacta gtgtagctta 1500

 tcttaaacat tttataaaac cttcagatgt ctttaagcag attggaagta 1550

 tgcaagtgct tccttagcag ggacagtgga taatccttaa tggtttatca 1600

 tagatttcac cctcccccct tctcagaaga gtgagtatgc tcttaaatgt 1650

 caaacacatt tttgttgttt tgttttttaa atgatcagtg tctatttgat 1700

 gtgatgcaga tcttataaat ttgggaatta taatattgac atttctgtga 1750

 tttttatata tgtaatgtct taattgagat ttgtgttaag gcagaaataa 1800

 ttaggctagg gctcttagtt ttcattccta ttgccccaag tattgtcaaa 1850

 ctatggtatt attttaatgt tactttaaaa atccataatc tgctagtttt 1900

 gcatgtactt atatgaaaac agtgcagtaa gttgaaaact cagtatctat 1950

 ggaattgata aatgttgatc tggtgtagta tattttatcc gcattttctt 2000

 atattaaaaa atgttctgca tgattacatt ttatttgcct ttgt 2044

<210> 2396
<211> 344
<212> PRT
<213> Homo sapien

<400> 2396
 Met Lys Asp Leu Gly Ala Glu His Leu Ala Gly His Glu Gly Val
   1               5                  10                  15

 Gln Leu Leu Gly Leu Leu Asn Val Tyr Leu Glu Gln Glu Glu Arg
                  20                  25                  30

 Phe Gln Pro Arg Glu Lys Gly Leu Ser Leu Ile Glu Ala Thr Pro
                  35                  40                  45

 Glu Asn Asp Asn Thr Leu Cys Pro Gly Leu Arg Asn Ala Lys Val
                  50                  55                  60

 Glu Asp Leu Arg Ser Leu Ala Asn Phe Phe Gly Ser Cys Thr Glu
                  65                  70                  75

 Thr Phe Val Leu Ala Val Asn Ile Leu Asp Arg Phe Leu Ala Leu
                  80                  85                  90

 Met Lys Val Lys Pro Lys His Leu Ser Cys Ile Gly Val Cys Ser
                  95                 100                 105

 Phe Leu Leu Ala Ala Arg Ile Val Glu Glu Asp Cys Asn Ile Pro
                 110                 115                 120

 Ser Thr His Asp Val Ile Arg Ile Ser Gln Cys Lys Cys Thr Ala
                 125                 130                 135

 Ser Asp Ile Lys Arg Met Glu Lys Ile Ile Ser Glu Lys Leu His
                 140                 145                 150

 Tyr Glu Leu Glu Ala Thr Thr Ala Leu Asn Phe Leu His Leu Tyr
                 155                 160                 165

 His Thr Ile Ile Leu Cys His Thr Ser Glu Arg Lys Glu Ile Leu
                 170                 175                 180

 Ser Leu Asp Lys Leu Glu Ala Gln Leu Lys Ala Cys Asn Cys Arg
                 185                 190                 195

 Leu Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu Cys Leu
                 200                 205                 210

 Leu Asn Leu Glu Val Glu Thr Leu Lys Ser Val Glu Leu Leu Glu
                 215                 220                 225

 Ile Leu Leu Leu Val Lys Lys His Ser Lys Ile Asn Asp Thr Glu
                 230                 235                 240

 Phe Phe Tyr Trp Arg Glu Leu Val Ser Lys Cys Leu Ala Glu Tyr
                 245                 250                 255

 Ser Ser Pro Glu Cys Cys Lys Pro Asp Leu Lys Lys Leu Val Trp
                 260                 265                 270

 Ile Val Ser Arg Arg Thr Ala Gln Asn Leu His Asn Ser Tyr Tyr
                 275                 280                 285

 Ser Val Pro Glu Leu Pro Thr Ile Pro Glu Gly Gly Cys Phe Asp
                 290                 295                 300

 Glu Ser Glu Ser Glu Asp Ser Cys Glu Asp Met Ser Cys Gly Glu
                 305                 310                 315

 Glu Ser Leu Ser Ser Ser Pro Pro Ser Asp Gln Glu Cys Thr Phe
                 320                 325                 330

 Phe Phe Asn Phe Lys Val Ala Gln Thr Leu Cys Phe Pro Ser
                 335                 340

<210> 2397
<211> 1865
<212> DNA
<213> Homo sapien

<400> 2397
 gagtgcgcac gcatcctgcc cgcggcgcgc gcgcaggtcg gtgcgtctgt 50

 cgggggcgcg ctcgggtacc tgtaccccac gtagtcgccg gttaccgatc 100

 ggactaagtt ccagtggtga tttacaagtc aagttaaaat gtccccagaa 150

 gtggccttga accgaatatc tccaatgctc tcccctttca tatctagcgt 200

 ggtccggaat ggaaaagtgg gactggatgc tacaaactgt ttgaggataa 250

 ctgacttaaa atctggctgc acatcattga ctcctgggcc caactgtgac 300

 cgatttaaac tgcacatacc atatgctgga gagacattaa agtgggatat 350

 cattttcaat gcccaatacc cagaactgcc tcccgatttt atctttggag 400

 aagatgctga attcctgcca gacccctcag ctttgcagaa tcttgcctcc 450

 tggaatcctt caaatcctga atgtctctta cttgtggtga aggaacttgt 500

 gcaacaatat caccaattcc aatgtagccg cctccgggag agctcccgcc 550

 tcatgtttga ataccagaca ttactggagg agccacagta tggagagaac 600

 atggaaattt atgctgggaa aaaaaacaac tggactggtg aattttcagc 650

 tcgtttcctt ttgaagctgc ccgtagattt cagcaatatc cccacatacc 700

 ttctcaagga tgtaaatgaa gaccctggag aagatgtggc cctcctctct 750

 gttagttttg aggacactga agccacccag gtgtacccca agctgtactt 800

 gtcacctcga attgagcatg cacttggagg ctcctcagct cttcatatcc 850

 cagcttttcc aggaggagga tgtctcattg attacgttcc tcaagtatgc 900

 cacctgctca ccaacaaggt gcagtacgtg attcaagggt atcacaaaag 950

 aagagagtat attgctgctt ttctcagtca ctttggcaca ggtgtcgtgg 1000

 aatatgatgc agaaggcttt acaaaactca ctctgctgct gatgtggaaa 1050

 gatttttgtt ttcttgtaca cattgacctg cctctgtttt tccctcgaga 1100

 ccagccaact ctcacatttc agtccgttta tcactttacc aacagtggac 1150

 agctttactc ccaggcccaa aaaaattatc cgtacagccc cagatgggat 1200

 ggaaatgaaa tggccaaaag agcaaaggga tgccagggga gcagagatgc 1250

 ctgcagcccg tgggagcaag tcctggcctt tgcagttgca aaaactggct 1300

 gcaagctgct ccagccccag aggaactggc caagctccag agggcctcct 1350

 tggagggcct cagagggaga gagaactgct cagtaatttt gatcactttg 1400

 ggcttatttc aaaacctttg tccctcagtt ccaggaggca gcatttgcca 1450

 atggaaagct ctaggaaaca ccagtcttga gaggtggcca gccagactgc 1500

 ctgtccacat gcgtgtcagc acatacagcc gcttcctgga agccgcctgg 1550

 aatgtcttca cggcagcgtt ttgctcacac agcagctttt gcacgcccca 1600

 ggcagccccg actgctgaaa tccaacttga gctggctggt ggtccctgga 1650

 tcctagagcc cttcacttcg ggttactccc tctttcttgc ctctatttct 1700

 tagttggaag aaataaactc acaaattatg gtgcagtaat tttccgggga 1750

 aagtaaagcc tcaggaatgc ccacgccttt cttccaaagc ctttgtctct 1800

 gagacctctt aagttctaag attaaatgcc cctcgctgtt tctcctctga 1850

 aaaaaaaaaa aaaaa 1865

<210> 2398
<211> 415
<212> PRT
<213> Homo sapien

<400> 2398
 Met Ser Pro Glu Val Ala Leu Asn Arg Ile Ser Pro Met Leu Ser
   1               5                  10                  15

 Pro Phe Ile Ser Ser Val Val Arg Asn Gly Lys Val Gly Leu Asp
                  20                  25                  30

 Ala Thr Asn Cys Leu Arg Ile Thr Asp Leu Lys Ser Gly Cys Thr
                  35                  40                  45

 Ser Leu Thr Pro Gly Pro Asn Cys Asp Arg Phe Lys Leu His Ile
                  50                  55                  60

 Pro Tyr Ala Gly Glu Thr Leu Lys Trp Asp Ile Ile Phe Asn Ala
                  65                  70                  75

 Gln Tyr Pro Glu Leu Pro Pro Asp Phe Ile Phe Gly Glu Asp Ala
                  80                  85                  90

 Glu Phe Leu Pro Asp Pro Ser Ala Leu Gln Asn Leu Ala Ser Trp
                  95                 100                 105

 Asn Pro Ser Asn Pro Glu Cys Leu Leu Leu Val Val Lys Glu Leu
                 110                 115                 120

 Val Gln Gln Tyr His Gln Phe Gln Cys Ser Arg Leu Arg Glu Ser
                 125                 130                 135

 Ser Arg Leu Met Phe Glu Tyr Gln Thr Leu Leu Glu Glu Pro Gln
                 140                 145                 150

 Tyr Gly Glu Asn Met Glu Ile Tyr Ala Gly Lys Lys Asn Asn Trp
                 155                 160                 165

 Thr Gly Glu Phe Ser Ala Arg Phe Leu Leu Lys Leu Pro Val Asp
                 170                 175                 180

 Phe Ser Asn Ile Pro Thr Tyr Leu Leu Lys Asp Val Asn Glu Asp
                 185                 190                 195

 Pro Gly Glu Asp Val Ala Leu Leu Ser Val Ser Phe Glu Asp Thr
                 200                 205                 210

 Glu Ala Thr Gln Val Tyr Pro Lys Leu Tyr Leu Ser Pro Arg Ile
                 215                 220                 225

 Glu His Ala Leu Gly Gly Ser Ser Ala Leu His Ile Pro Ala Phe
                 230                 235                 240

 Pro Gly Gly Gly Cys Leu Ile Asp Tyr Val Pro Gln Val Cys His
                 245                 250                 255

 Leu Leu Thr Asn Lys Val Gln Tyr Val Ile Gln Gly Tyr His Lys
                 260                 265                 270

 Arg Arg Glu Tyr Ile Ala Ala Phe Leu Ser His Phe Gly Thr Gly
                 275                 280                 285

 Val Val Glu Tyr Asp Ala Glu Gly Phe Thr Lys Leu Thr Leu Leu
                 290                 295                 300

 Leu Met Trp Lys Asp Phe Cys Phe Leu Val His Ile Asp Leu Pro
                 305                 310                 315

 Leu Phe Phe Pro Arg Asp Gln Pro Thr Leu Thr Phe Gln Ser Val
                 320                 325                 330

 Tyr His Phe Thr Asn Ser Gly Gln Leu Tyr Ser Gln Ala Gln Lys
                 335                 340                 345

 Asn Tyr Pro Tyr Ser Pro Arg Trp Asp Gly Asn Glu Met Ala Lys
                 350                 355                 360

 Arg Ala Lys Gly Cys Gln Gly Ser Arg Asp Ala Cys Ser Pro Trp
                 365                 370                 375

 Glu Gln Val Leu Ala Phe Ala Val Ala Lys Thr Gly Cys Lys Leu
                 380                 385                 390

 Leu Gln Pro Gln Arg Asn Trp Pro Ser Ser Arg Gly Pro Pro Trp
                 395                 400                 405

 Arg Ala Ser Glu Gly Glu Arg Thr Ala Gln
                 410                 415

<210> 2399
<211> 3259
<212> DNA
<213> Homo sapien

<400> 2399
 gggccgggtc cgggagcccc agggcagccg ccccgccgag tcgcagtgtc 50

 gggggctgcg gggtgtctcg gggccctggg gtgagtgcgg ggcgcgggcc 100

 gaggtttgca gggccctgtg agcgcgccca ggcacgtgtt gcttcgggac 150

 gggccagccg gtgggtgaac cctgccagcc acgcgtgggg cgggcccctg 200

 gcacatctcc agaccattgt ctcctgtgcc agaagctttg taggtgcaac 250

 ttccccttgg agcagctgtg ggtgcggatc cagcggacga atcccgaggc 300

 gtctcagaga gagcctggac agccgctgga gcctttcccg agtgggtcct 350

 tccaacaccg ctacagcagg aaagccatcc ccctagggtc ctgtccatcg 400

 gaaactcctg tcctggggag tctgcctgcc tggcctcagg acacaggcca 450

 actaagctgg ccccgaaatc cagaatgcat ccagagggaa ggcacagtgt 500

 caccttcgtc ccctccggag ctgcacgtgg cctgagcagg atggtgccct 550

 ccagcccagc ggtggagaag caggtgcccg tggaacctgg gcctgacccc 600

 gagctccggt cctggcggcg cctcgtgtgc tacctttgct tctacggctt 650

 catggcgcag atacggccag gggagagctt catcaccccc tacctcctgg 700

 ggcccgacaa gaacttcacg cgggagcagg tcacgaacga gatcacgccg 750

 gtgctgtcgt actcctacct ggccgtgctg gtgccggtgt tcctgctcac 800

 cgactacctg cgctacacgc cggtgctgct gctgcagggg ctcagcttcg 850

 tgtcggtgtg gctgctgctg ctgctgggcc actcggtggc gcacatgcag 900

 ctcatggagc tcttctacag cgtcaccatg gccgcgcgca tcgcctattc 950

 ctcctacatc ttctctctcg tgcggcccgc gcgctaccag cgtgtggccg 1000

 gctactcgcg cgctgcggtg ctgctgggcg tgttcaccag ctccgtgctg 1050

 ggccagctgc tggtcactgt gggccgagtc tccttctcca cgctcaacta 1100

 catctcgctg gccttcctca ccttcagcgt ggtcctcgcc ctcttcctga 1150

 agcgccccaa gcgcagcctc ttcttcaacc gcgacgaccg ggggcggtgc 1200

 gaaacctcgg cttcggagct ggagcgcatg aatcccggcc caggcgggaa 1250

 gctgggacac gccctgcggg tggcctgtgg ggactcagtg ctggcgcgga 1300

 tgctgcggga gctgggggac agcctgcggc ggccgcagct gcgcctgtgg 1350

 tccctctggt gggtcttcaa ctcggccggc tactacctgg tggtctacta 1400

 cgtgcacatc ctgtggaacg aggtggaccc caccaccaac agtgcgcggg 1450

 tctacaacgg cgcggcagat gctgcctcca cgctgctggg cgccatcacg 1500

 tccttcgccg cgggcttcgt gaagatccgc tgggcgcgct ggtccaagct 1550

 gctcatcgcg ggcgtcacgg ccacgcaggc ggggctggtc ttccttctgg 1600

 cgcacacgcg ccacccgagc agcatctggc tgtgctatgc ggccttcgtg 1650

 ctgttccgcg gctcctacca gttcctcgtg cccatcgcca cctttcagat 1700

 tgcatcttct ctgtctaaag agctctgtgc cctggtcttc ggggtcaaca 1750

 cgttctttgc caccatcgtc aagaccatca tcactttcat tgtctcggac 1800

 gtgcggggcc tgggcctccc ggtccgcaag cagttccagt tatactccgt 1850

 gtacttcctg atcctgtcca tcatctactt cttgggggcc atgctggatg 1900

 gcctgcggca ctgccagcgg ggccaccacc cgcggcagcc cccggcccag 1950

 ggcctgagga gtgccgcgga ggagaaggca gcacaggcac tgagcgtgca 2000

 ggacaagggc ctcggaggcc tgcagccagc ccagagcccg ccgctttccc 2050

 cagaagacag cctgggggct gtggggccag cctccctgga gcagagacag 2100

 agcgacccat acctggccca ggccccggcc ccgcaggcag ctgaattcct 2150

 gagcccagtg acaacccctt ccccctgcac tctgtcgtcc gcccaagcct 2200

 caggccctga ggctgcagat gagacttgtc cccagctggc tgtccatcct 2250

 cctggtgtca gcaagctggg tttgcagtgt cttccaagcg acggtgttca 2300

 gaatgtgaac cagtgactct cgggcgcccc tgtggtaact ttgcaggcgg 2350

 ccctcagtgc atccccacga cccctgcctc gagggccgcc tgccttagca 2400

 atgggggcct ccgcttatcc tgctagcagg ccccctagga ttccccctgc 2450

 cctgtgccgc actctggcgg tggccacagc gtgctggcga cactcagggc 2500

 agctgcctgg ccatgctgtc cctgcactgt gccccgcggg ctttgttgct 2550

 ggaagaggtg ggtggtgggc ttctgcgtcc accaggcctc actggctcat 2600

 gccccttggg gggcttgaga caaatccttt ctgcccccca gggctagtga 2650

 agtggcctct tggataccag ctcaggggac actggcccca caggagttgt 2700

 gagccctcta gggcagggtg ggagccggga ccctcaggtg tagctgagct 2750

 gtgacattgc tggtcatcct tggtgctctt gcttttttga aagatgcttt 2800

 tttttttttt aactgacgta gaatgaagaa ctgcatgtgg cttctctgtc 2850

 tctgtggaaa agccatctca ggttggcggc agacacattg tcatcagagg 2900

 ggagcagcgg ctctggtcct cggagctggt tcctctctcc caccctaagg 2950

 gcagccctcc atggtcctgt ctgtccttct gaagtgtgtc catcctgacc 3000

 tgcgggtcct cagctgctcc cacacttgtg ccagcccgga ggggactggt 3050

 cccggtcacc gcggacgtgc tggccttggt atgtgccagg cttgcctggg 3100

 ctgggcagcc ttgggggggc tgcctttgtg gtgggcgctg gggaagtacg 3150

 tcccagcggc ctcagggtct aaggagcgct agtgccttgc ccacaggtgc 3200

 gggaccatct gatgtgatgt gaatactctt cccacataca ttaaacacac 3250

 ttaagtgag 3259

<210> 2400
<211> 591
<212> PRT
<213> Homo sapien

<400> 2400
 Met Val Pro Ser Ser Pro Ala Val Glu Lys Gln Val Pro Val Glu
   1               5                  10                  15

 Pro Gly Pro Asp Pro Glu Leu Arg Ser Trp Arg Arg Leu Val Cys
                  20                  25                  30

 Tyr Leu Cys Phe Tyr Gly Phe Met Ala Gln Ile Arg Pro Gly Glu
                  35                  40                  45

 Ser Phe Ile Thr Pro Tyr Leu Leu Gly Pro Asp Lys Asn Phe Thr
                  50                  55                  60

 Arg Glu Gln Val Thr Asn Glu Ile Thr Pro Val Leu Ser Tyr Ser
                  65                  70                  75

 Tyr Leu Ala Val Leu Val Pro Val Phe Leu Leu Thr Asp Tyr Leu
                  80                  85                  90

 Arg Tyr Thr Pro Val Leu Leu Leu Gln Gly Leu Ser Phe Val Ser
                  95                 100                 105

 Val Trp Leu Leu Leu Leu Leu Gly His Ser Val Ala His Met Gln
                 110                 115                 120

 Leu Met Glu Leu Phe Tyr Ser Val Thr Met Ala Ala Arg Ile Ala
                 125                 130                 135

 Tyr Ser Ser Tyr Ile Phe Ser Leu Val Arg Pro Ala Arg Tyr Gln
                 140                 145                 150

 Arg Val Ala Gly Tyr Ser Arg Ala Ala Val Leu Leu Gly Val Phe
                 155                 160                 165

 Thr Ser Ser Val Leu Gly Gln Leu Leu Val Thr Val Gly Arg Val
                 170                 175                 180

 Ser Phe Ser Thr Leu Asn Tyr Ile Ser Leu Ala Phe Leu Thr Phe
                 185                 190                 195

 Ser Val Val Leu Ala Leu Phe Leu Lys Arg Pro Lys Arg Ser Leu
                 200                 205                 210

 Phe Phe Asn Arg Asp Asp Arg Gly Arg Cys Glu Thr Ser Ala Ser
                 215                 220                 225

 Glu Leu Glu Arg Met Asn Pro Gly Pro Gly Gly Lys Leu Gly His
                 230                 235                 240

 Ala Leu Arg Val Ala Cys Gly Asp Ser Val Leu Ala Arg Met Leu
                 245                 250                 255

 Arg Glu Leu Gly Asp Ser Leu Arg Arg Pro Gln Leu Arg Leu Trp
                 260                 265                 270

 Ser Leu Trp Trp Val Phe Asn Ser Ala Gly Tyr Tyr Leu Val Val
                 275                 280                 285

 Tyr Tyr Val His Ile Leu Trp Asn Glu Val Asp Pro Thr Thr Asn
                 290                 295                 300

 Ser Ala Arg Val Tyr Asn Gly Ala Ala Asp Ala Ala Ser Thr Leu
                 305                 310                 315

 Leu Gly Ala Ile Thr Ser Phe Ala Ala Gly Phe Val Lys Ile Arg
                 320                 325                 330

 Trp Ala Arg Trp Ser Lys Leu Leu Ile Ala Gly Val Thr Ala Thr
                 335                 340                 345

 Gln Ala Gly Leu Val Phe Leu Leu Ala His Thr Arg His Pro Ser
                 350                 355                 360

 Ser Ile Trp Leu Cys Tyr Ala Ala Phe Val Leu Phe Arg Gly Ser
                 365                 370                 375

 Tyr Gln Phe Leu Val Pro Ile Ala Thr Phe Gln Ile Ala Ser Ser
                 380                 385                 390

 Leu Ser Lys Glu Leu Cys Ala Leu Val Phe Gly Val Asn Thr Phe
                 395                 400                 405

 Phe Ala Thr Ile Val Lys Thr Ile Ile Thr Phe Ile Val Ser Asp
                 410                 415                 420

 Val Arg Gly Leu Gly Leu Pro Val Arg Lys Gln Phe Gln Leu Tyr
                 425                 430                 435

 Ser Val Tyr Phe Leu Ile Leu Ser Ile Ile Tyr Phe Leu Gly Ala
                 440                 445                 450

 Met Leu Asp Gly Leu Arg His Cys Gln Arg Gly His His Pro Arg
                 455                 460                 465

 Gln Pro Pro Ala Gln Gly Leu Arg Ser Ala Ala Glu Glu Lys Ala
                 470                 475                 480

 Ala Gln Ala Leu Ser Val Gln Asp Lys Gly Leu Gly Gly Leu Gln
                 485                 490                 495

 Pro Ala Gln Ser Pro Pro Leu Ser Pro Glu Asp Ser Leu Gly Ala
                 500                 505                 510

 Val Gly Pro Ala Ser Leu Glu Gln Arg Gln Ser Asp Pro Tyr Leu
                 515                 520                 525

 Ala Gln Ala Pro Ala Pro Gln Ala Ala Glu Phe Leu Ser Pro Val
                 530                 535                 540

 Thr Thr Pro Ser Pro Cys Thr Leu Ser Ser Ala Gln Ala Ser Gly
                 545                 550                 555

 Pro Glu Ala Ala Asp Glu Thr Cys Pro Gln Leu Ala Val His Pro
                 560                 565                 570

 Pro Gly Val Ser Lys Leu Gly Leu Gln Cys Leu Pro Ser Asp Gly
                 575                 580                 585

 Val Gln Asn Val Asn Gln
                 590

<210> 2401
<211> 504
<212> DNA
<213> Homo sapien

<400> 2401
 cacccaccca ggcccaggct ccttcccctc catcatcccc ttaccagcac 50

 ctagaaccat ccagggctga aaagtcccct ccaaaccacg tgatgaggaa 100

 cttgaggcaa gtcaccagcc cctgatcatt tcgcctaaaa gagcaaggac 150

 tagagttcct gacctccagg ccagtccctg atccctgacc taatgttatc 200

 gcggaatgat gacccagggc tcctcagagc aggaactcca ctatgcatct 250

 ctgcagaggc tgccagtgcc cagcagtgag ggacctgacc tcaggggcag 300

 agacaagaga ggcaccaagg aggatccaag agctgactat gcctgcattg 350

 ctgagaacaa acccacctga gcaccccaga caccttcctc aacccaggcg 400

 ggtggacagg gtccccctgt ggtccagcca gtaaaaacca tggtcccccc 450

 acttctgtgt ctcagtcctc tcagtccatc tcgagcctcc gttcaaattg 500

 atca 504

<210> 2402
<211> 53
<212> PRT
<213> Homo sapien

<400> 2402
 Met Thr Gln Gly Ser Ser Glu Gln Glu Leu His Tyr Ala Ser Leu
   1               5                  10                  15

 Gln Arg Leu Pro Val Pro Ser Ser Glu Gly Pro Asp Leu Arg Gly
                  20                  25                  30

 Arg Asp Lys Arg Gly Thr Lys Glu Asp Pro Arg Ala Asp Tyr Ala
                  35                  40                  45

 Cys Ile Ala Glu Asn Lys Pro Thr
                  50

<210> 2403
<211> 1116
<212> DNA
<213> Homo sapien

<400> 2403
 ccacaagctg gccccttggc ctcctagaga ccctgacatc tcctccagca 50

 gcatctgtcc tctctcctca gggaggcaag catttgatgc tcgaggtccc 100

 tggcagttgt ggtccttggc aagtgatgtg tgagtcccgt gtgtcatagg 150

 aagctcccca tccccatctg gtgaccaaag gcctggctac aagtagtgag 200

 tccttcctcc tccacccaga cctcactgct cagatcccct tcgccaactg 250

 ggacatcttc cgacatggcc tggatgctgt tgctcatctt gatcatggtc 300

 catccaggat cctgtgctct ctgggtgtcc cagccccctg agattcgtac 350

 cctggaagga tcctctgcct tcctgccctg ctccttcaat gccagccaag 400

 ggagactggc cattggctcc gtcacgtggt tccgagatga ggtggttcca 450

 gggaaggagg tgaggaatgg aaccccagag ttcaggggcc gcctggcccc 500

 acttgcttct tcccgtttcc tccatgacca ccaggctgag ctgcacatcc 550

 gggacgtgcg aggccatgac gccagcatct acgtgtgcag agtggaggtg 600

 ctgggccttg gtgtcgggac agggaatggg actcggctgg tggtggagaa 650

 agaacatcct cagctagggg ctggtacagt cctcctcctt cgggctggat 700

 tctatgctgt cagctttctc tctgtggccg tgggcagcac cgtctattac 750

 cagggcaaat atgccaaatc tactctctcc ggattccccc aactctgaac 800

 tttcccttcc accaggtctg acctggaaag gtccaagaag gcagctgccg 850

 gctgtggtcc cagcgcccct cccaccacca tgtgggagct cagcacatct 900

 gcttccccca gtcccaggag gctgagcctg attgtcctga gaaatgggaa 950

 ggatcagata tgactcctcc ttggcaactg ccctttcctg ccaggcccac 1000

 acataccctc ttctggctgt taggggagct tgggtccctg aacactgtca 1050

 ttcacccaat aaattactat ttgaccccag agtgggtgga agggtgaaaa 1100

 aaaaaaaaaa aaaaaa 1116

<210> 2404
<211> 177
<212> PRT
<213> Homo sapien

<400> 2404
 Met Ala Trp Met Leu Leu Leu Ile Leu Ile Met Val His Pro Gly
   1               5                  10                  15

 Ser Cys Ala Leu Trp Val Ser Gln Pro Pro Glu Ile Arg Thr Leu
                  20                  25                  30

 Glu Gly Ser Ser Ala Phe Leu Pro Cys Ser Phe Asn Ala Ser Gln
                  35                  40                  45

 Gly Arg Leu Ala Ile Gly Ser Val Thr Trp Phe Arg Asp Glu Val
                  50                  55                  60

 Val Pro Gly Lys Glu Val Arg Asn Gly Thr Pro Glu Phe Arg Gly
                  65                  70                  75

 Arg Leu Ala Pro Leu Ala Ser Ser Arg Phe Leu His Asp His Gln
                  80                  85                  90

 Ala Glu Leu His Ile Arg Asp Val Arg Gly His Asp Ala Ser Ile
                  95                 100                 105

 Tyr Val Cys Arg Val Glu Val Leu Gly Leu Gly Val Gly Thr Gly
                 110                 115                 120

 Asn Gly Thr Arg Leu Val Val Glu Lys Glu His Pro Gln Leu Gly
                 125                 130                 135

 Ala Gly Thr Val Leu Leu Leu Arg Ala Gly Phe Tyr Ala Val Ser
                 140                 145                 150

 Phe Leu Ser Val Ala Val Gly Ser Thr Val Tyr Tyr Gln Gly Lys
                 155                 160                 165

 Tyr Ala Lys Ser Thr Leu Ser Gly Phe Pro Gln Leu
                 170                 175

<210> 2405
<211> 1013
<212> DNA
<213> Homo sapien

<400> 2405
 gcttccaaac ccagggcttg cgcttgcctt tgcctcttcc accgcgcagg 50

 gaccatgtcg gcggagaccg cgagcggccc cacagaggac caggtggaaa 100

 tcctggagta caacttcaac aaggtcgaca agcacccgga ttccaccacg 150

 ctgtgcctca tcgcggccga ggcaggcctt tccgaggagg agacccagaa 200

 atggtttaag cagcgcctgg caaagtggcg gcgctcagaa ggcctgccct 250

 cagagtgcag atccgtcaca gactaaggag atggcaggca ttgacagctt 300

 cactccatga aggccatctc tgtttctctc ctccgcttaa ccaagctgtt 350

 gtggtttttc agcatagtgt tgtatgttcc attgctagct gtcctgctgt 400

 ttaacacagt gttgtatttt ttttctaaat gtacataatt agaaaagaaa 450

 ataacaatag gaagctatgt gtatcttctg tgtaaagcag tggcttcact 500

 ggaaaaatgg tgtggctagc atttcccttt gagtcatgat gacagatggt 550

 gtgaaaacca tctaagtttg cttttgacca tcacctccca gtagcaattt 600

 gctttcataa tccatttagc aatccaggcc tctgttgaaa agataatatg 650

 agggagaagg gaacacattt ccttctgaac ttacttccct aagtcacttt 700

 ccttatgtat catctaatac aatgatggtt gagtgaaaat acagaagggg 750

 tgtttgagta ttcagatttc ataaaacact tccttggaat atagctgcat 800

 taacttggaa agaagcctgt tgggccagaa gacagaaact ccaactggca 850

 aaaaagcaag catctaagaa aaaaaaccac caaagttctt gaatttacta 900

 tatttaaatg cattggttaa gtttattttg ctaaataaag tgaactgctt 950

 tttgtctcta aaatgatatt ctaaataaaa ccttaacttt ttgttgaaaa 1000

 aaaaaaaaaa aaa 1013

<210> 2406
<211> 73
<212> PRT
<213> Homo sapien

<400> 2406
 Met Ser Ala Glu Thr Ala Ser Gly Pro Thr Glu Asp Gln Val Glu
   1               5                  10                  15

 Ile Leu Glu Tyr Asn Phe Asn Lys Val Asp Lys His Pro Asp Ser
                  20                  25                  30

 Thr Thr Leu Cys Leu Ile Ala Ala Glu Ala Gly Leu Ser Glu Glu
                  35                  40                  45

 Glu Thr Gln Lys Trp Phe Lys Gln Arg Leu Ala Lys Trp Arg Arg
                  50                  55                  60

 Ser Glu Gly Leu Pro Ser Glu Cys Arg Ser Val Thr Asp
                  65                  70

<210> 2407
<211> 2527
<212> DNA
<213> Homo sapien

<400> 2407
 tccgggcctg gcctgtacgg tcgccgccgt tccctggaag tagcaacttc 50

 cctaccccac cccagtcctg gtccccgtcc agccgctgac gtgaagatga 100

 gcagctcaga ggaggtgtcc tggatttcct ggttctgtgg gctccgtggc 150

 aatgaattct tctgtgaagt ggatgaagac tacatccagg acaaatttaa 200

 tcttactgga ctcaatgagc aggtccctca ctaccgacaa gctctagaca 250

 tgatcttgga cctggagcct gatgaagaac tggaagacaa ccccaaccag 300

 agtgacctga ttgagcaggc agccgagatg ctttatggat tgatccacgc 350

 ccgctacatc cttaccaacc gtggcatcgc ccagatgttg gaaaagtacc 400

 agcaaggaga ctttggttac tgtcctcgtg tgtactgtga gaaccagcca 450

 atgcttccca ttggcctttc agacatccca ggtgaagcca tggtgaagct 500

 ctactgcccc aagtgcatgg atgtgtacac acccaagtca tcaagacacc 550

 atcacacgga tggcgcctac ttcggcactg gtttccctca catgctcttc 600

 atggtgcatc ccgagtaccg gcccaagaga cctgccaacc agtttgtgcc 650

 caggctctac ggtttcaaga tccatgcgat ggcctaccag ctgcagctcc 700

 aagccgccag caacttcaag agcccagtca agacgattcg ctgattccct 750

 cccccacctg tcctgcagtc tttgactttt cctttctttt ttgccaccct 800

 ttcaggaacc ctgtatggtt tttagtttaa attaaaggag tcgttattgt 850

 ggtgggaata tgaaataaag tagaagaaaa ggccatgaaa aaaaaaaaaa 900

 aaaaaaaaaa aaaggtttgt gttctcgacg ccttggtagt tggcataggc 950

 taaagaaaag ggatctcagc cccgaggaag ggtcaccctc ctagagatag 1000

 ctactacccc gtctcaggag accctggtat ttctagagca cgctttgctt 1050

 tcaccaaacc caaggaggtg acaggaggag cccccgcaca ggacctaaga 1100

 atgctgtgac cagaagatgg gatcgcggaa cagcagcagt gcaggatccg 1150

 gtccggagac ccctccgagg gcttgccccg aagaggggct ggcctgcgtc 1200

 ggagtgagga agaggaagaa gaggatgaag atgtggatct ggcccaggta 1250

 ctggcctatc tcctccgcag aggccaagtg aggttggtgc agggaggagg 1300

 tgcagcaaat ttacaattca ttcaggccct cttggactca gaggaagaga 1350

 atgacagagc ttgggatggt cgtcttgggg atcgatacaa cccacctgtg 1400

 gatgctaccc ctgacacccg ggagctggaa ttcctggagt tgtgaacgcc 1450

 gcggactccg gagccgcaca aaccagggct cgccatgaag ccaggattca 1500

 gtcccccgtg ggggtggctt tggcggccga gggggctttg gtgaccgtgg 1550

 tggtcgtgga ggccgagggg gctttggcgg gggccgaggt cgaggcggag 1600

 gctttagagg tcgtggacga ggaggaggtg gaggcggcgg cggcggtgga 1650

 ggaggaggaa gaggtggagg cttccattct ggtggcaacc ggggtcgtgg 1700

 tcggggagga aaaagaggaa accagtcggg gaagaatgtg atggtggagc 1750

 cgcatcggac tgagggtgtc ttcatttgtc gaggaaagga gatgcactgg 1800

 tcaccaagaa cctggtcctg ggaatcaagt tatggagaga agagagtctc 1850

 gattcggaag gagatgacaa aattgagtac cgagcctgga accccttccg 1900

 ctccaagcta gcagcagcaa tcctgggtgg tgtggaccag atccacatca 1950

 aaccgggggc taaggttctc tacctcgggg ctgcctcggg caccacggtc 2000

 tcccatgtct ctgacatcgt tggtccggat ggtctagtct atgcagtcga 2050

 gtttccccac cgctctggcc gtgacctcat taacttggcc aagaagagga 2100

 ccaacatcat tcctgtgatc gaggatgctc gacacccaca caaataccgc 2150

 atgctcatcg caatggtgga tgtgatcttt gctgatgtgg cccagccaga 2200

 ccagacccgg aatgtggccc tgaaagccca caccttcctg cgctaatgga 2250

 ggacactttg tgatttccat taaggccaac tgcattgact ccacagccta 2300

 gcggtcaggc cgtgtttgcc tccgaagtga aaaagatgca acaggagaac 2350

 atgaagccgc aggagcagtt gacccttgag ccatatgaaa gagaccatgc 2400

 cgtggtcgtg ggagtgtaca ggccaccccc caaggtgaag aactgaagtt 2450

 cagcgctgtc aggattgcga gagatgtgtg ttgatactgt tgcccgtgtg 2500

 tttttctaat taaaagactc ctccgtc 2527

<210> 2408
<211> 215
<212> PRT
<213> Homo sapien

<400> 2408
 Met Ser Ser Ser Glu Glu Val Ser Trp Ile Ser Trp Phe Cys Gly
   1               5                  10                  15

 Leu Arg Gly Asn Glu Phe Phe Cys Glu Val Asp Glu Asp Tyr Ile
                  20                  25                  30

 Gln Asp Lys Phe Asn Leu Thr Gly Leu Asn Glu Gln Val Pro His
                  35                  40                  45

 Tyr Arg Gln Ala Leu Asp Met Ile Leu Asp Leu Glu Pro Asp Glu
                  50                  55                  60

 Glu Leu Glu Asp Asn Pro Asn Gln Ser Asp Leu Ile Glu Gln Ala
                  65                  70                  75

 Ala Glu Met Leu Tyr Gly Leu Ile His Ala Arg Tyr Ile Leu Thr
                  80                  85                  90

 Asn Arg Gly Ile Ala Gln Met Leu Glu Lys Tyr Gln Gln Gly Asp
                  95                 100                 105

 Phe Gly Tyr Cys Pro Arg Val Tyr Cys Glu Asn Gln Pro Met Leu
                 110                 115                 120

 Pro Ile Gly Leu Ser Asp Ile Pro Gly Glu Ala Met Val Lys Leu
                 125                 130                 135

 Tyr Cys Pro Lys Cys Met Asp Val Tyr Thr Pro Lys Ser Ser Arg
                 140                 145                 150

 His His His Thr Asp Gly Ala Tyr Phe Gly Thr Gly Phe Pro His
                 155                 160                 165

 Met Leu Phe Met Val His Pro Glu Tyr Arg Pro Lys Arg Pro Ala
                 170                 175                 180

 Asn Gln Phe Val Pro Arg Leu Tyr Gly Phe Lys Ile His Ala Met
                 185                 190                 195

 Ala Tyr Gln Leu Gln Leu Gln Ala Ala Ser Asn Phe Lys Ser Pro
                 200                 205                 210

 Val Lys Thr Ile Arg
                 215

<210> 2409
<211> 436
<212> DNA
<213> Homo sapien

<400> 2409
 gttcctcacc atggactgga cctggaggat cctcttcttg gtggcagcag 50

 ccacaggagc ccactcccag gtgcagctgg tgcaatctgg ggctgaggtg 100

 aagaagcctg gggcctcagt gaaggtctcc tgcgaggctt ctggatacac 150

 cttcaccggc cactatatgc actgggtgcg acaggcccct ggacaagggc 200

 ttgagtggat gggatggatc aaccctaaca gtggtggcac aaactatgca 250

 gagaagtttc agggcagggt caccatcacc agggacacgt ccatcaacac 300

 agcctacatg gagctgagca ggctgagatc tgacgacacg gccgtgtatt 350

 actgtgcgag agcctcatat tgtggttatg actgctatta cttctttgac 400

 tactggggcc agggaaccct ggtcaccgtc tcctca 436

<210> 2410
<211> 141
<212> PRT
<213> Homo sapien

<400> 2410
 Met Asp Trp Thr Trp Arg Ile Leu Phe Leu Val Ala Ala Ala Thr
   1               5                  10                  15

 Gly Ala His Ser Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val
                  20                  25                  30

 Lys Lys Pro Gly Ala Ser Val Lys Val Ser Cys Glu Ala Ser Gly
                  35                  40                  45

 Tyr Thr Phe Thr Gly His Tyr Met His Trp Val Arg Gln Ala Pro
                  50                  55                  60

 Gly Gln Gly Leu Glu Trp Met Gly Trp Ile Asn Pro Asn Ser Gly
                  65                  70                  75

 Gly Thr Asn Tyr Ala Glu Lys Phe Gln Gly Arg Val Thr Ile Thr
                  80                  85                  90

 Arg Asp Thr Ser Ile Asn Thr Ala Tyr Met Glu Leu Ser Arg Leu
                  95                 100                 105

 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ser Tyr
                 110                 115                 120

 Cys Gly Tyr Asp Cys Tyr Tyr Phe Phe Asp Tyr Trp Gly Gln Gly
                 125                 130                 135

 Thr Leu Val Thr Val Ser
                 140

<210> 2411
<211> 365
<212> DNA
<213> Homo sapien

<400> 2411
 taaaaggtgt ccagtgtgag gtgcagttgg tggagtccgg gggaggctta 50

 gttcagcctg gggggtccct gagactctcc tgtgcagcct ctggattcac 100

 cttcagtacc tacaggatgc actgggtccg ccaagctcca gggaaggggc 150

 tggtgtgggt ctcacgtatt aatagtgatg ggagtagcac agactacgcg 200

 gactccgtgg agggccgatt caccatctcc agagacaacg ccaagaacac 250

 gctgtatctg caaatgaaca gtctgagagc cgaagacacg gctgtgtatt 300

 actgtgcaag atccaattac tactttgact cctggggcca gggaaccctg 350

 gtcaccgtct cctca 365

<210> 2412
<211> 993
<212> DNA
<213> Homo sapien

<400> 2412
 agaccttcgg gtagcaactg tcaccttgat gctggcgatc ctgagctcct 50

 cactggctga gggcagagac tctcccgagg atttcgtgta ccagtttaag 100

 ggcctgtgct acttcaccaa cgggacggag cgcgtgcggg gtgtgaccag 150

 acacatctat aaccgagagg agtacgtgcg cttcgacagc gacgtggggg 200

 tgtaccgggc agtgacgccg caggggcggc ctgttgccga gtactggaac 250

 agccagaagg aagtcctaga gggggcccgg gcgtcggtgg acagggtgtg 300

 cagacacaac tacgaggtgg cgtaccgcgg gatcctgcag aggagagtgg 350

 agcccacagt gaccatctcc ccatccagga cagaggccct caaccaccac 400

 aacctgctga tctgctcggt gacagatttc tatccaagcc agatcaaagt 450

 ccggtggttt cggaatgatc aggaggagac agccggcgtt gtgtccaccc 500

 ccctcattag gaacggtgac tggaccttcc agatcctggt gatgctggaa 550

 atgactcccc agcgtggaga tgtctacacc tgccacgtgg agcaccccag 600

 cctccagagc cccatcaccg tggagtggcg ggctcagtct gaatctgccc 650

 agagcaagat gctgagtggc gttggaggct tcgtgctggg gctgatcttc 700

 cttgggcttg gccttatcat ccgtcaaagg agtcggaaag ggcttctgca 750

 ctgactcctg agactgtttt aactaagact ggttatcact cttctgtgat 800

 gcctgcttgt ccctgcccag aattcccagc tgcctgtgtc agcttgtccc 850

 cctgagatca aagtcctaca gtggctgtca cgcaaccacc aggtcatctc 900

 ctttcatccc caccccaagg cgctggctgt gactctgctt cctgcactga 950

 cccagagcca ctgcctgtac atggccagct gcgtctactc agg 993

<210> 2413
<211> 4788
<212> DNA
<213> Homo sapien

<400> 2413
 tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa 50

 gctaagttgt ttatctcggc tgcggcggga actgcggacg gtggcgggcg 100

 agcggctcct ctgccagagt tgatattcac tgatggactc caaagaatca 150

 ttaactcctg gtagagaaga aaaccccagc agtgtgcttg ctcaggagag 200

 gggagatgtg atggacttct ataaaaccct aagaggagga gctactgtga 250

 aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc 300

 aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc 350

 gcagcagcca gatctgtcca aagcagtttc actctcaatg ggactgtata 400

 tgggagagac agaaacaaaa gtgatgggaa atgacctggg attcccacag 450

 cagggccaaa tcagcctttc ctcgggggaa acagacttaa agcttttgga 500

 agaaagcatt gcaaacctca ataggtcgac cagtgttcca gagaacccca 550

 agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt 600

 ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca 650

 gactggcacc aacggtggca atgtgaaatt gtataccaca gaccaaagca 700

 cctttgacat tttgcaggat ttggagtttt cttctgggtc cccaggtaaa 750

 gagacgaatg agagtccttg gagatcagac ctgttgatag atgaaaactg 800

 tttgctttct cctctggcgg gagaagacga ttcattcctt ttggaaggaa 850

 actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa 900

 attaaggata atggagatct ggttttgtca agccccagta atgtaacact 950

 gccccaagtg aaaacagaaa aagaagattt catcgaactc tgcacccctg 1000

 gggtaattaa gcaagagaaa ctgggcacag tttactgtca ggcaagcttt 1050

 cctggagcaa atataattgg taataaaatg tctgccattt ctgttcatgg 1100

 tgtgagtacc tctggaggac agatgtacca ctatgacatg aatacagcat 1150

 ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca 1200

 attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga 1250

 caacttgact tctctgggga ctctgaactt ccctggtcga acagtttttt 1300

 ctaatggcta ttcaagcccc agcatgagac cagatgtaag ctctcctcca 1350

 tccagctcct caacagcaac aacaggacca cctcccaaac tctgcctggt 1400

 gtgctctgat gaagcttcag gatgtcatta tggagtctta acttgtggaa 1450

 gctgtaaagt tttcttcaaa agagcagtgg aaggacagca caattaccta 1500

 tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg 1550

 cccagcatgc cgctatcgaa aatgtcttca ggctggaatg aacctggaag 1600

 ctcgaaaaac aaagaaaaaa ataaaaggaa ttcagcaggc cactacagga 1650

 gtctcacaag aaacctctga aaatcctggt aacaaaacaa tagttcctgc 1700

 aacgttacca caactcaccc ctaccctggt gtcactgttg gaggttattg 1750

 aacctgaagt gttatatgca ggatatgata gctctgttcc agactcaact 1800

 tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc 1850

 agcagtgaaa tgggcaaagg caataccagg tttcaggaac ttacacctgg 1900

 atgaccaaat gaccctactg cagtactcct ggatgtttct tatggcattt 1950

 gctctggggt ggagatcata tagacaatca agtgcaaacc tgctgtgttt 2000

 tgctcctgat ctgattatta atgagcagag aatgactcta ccctgcatgt 2050

 acgaccaatg taaacacatg ctgtatgttt cctctgagtt acacaggctt 2100

 caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc 2150

 ttcagttcct aaggacggtc tgaagagcca agagctattt gatgaaatta 2200

 gaatgaccta catcaaagag ctaggaaaag ccattgtcaa gagggaagga 2250

 aactccagcc agaactggca gcggttttat caactgacaa aactcttgga 2300

 ttctatgcat gaagtggttg aaaatctcct taactattgc ttccaaacat 2350

 ttttggataa gaccatgagt attgaattcc ccgagatgtt agctgaaatc 2400

 atcaccaatc agataccaaa atattcaaat ggaaatatca aaaaacttct 2450

 gtttcatcaa aagtgactgc cttaataaga atggttgcct taaagaaagt 2500

 cgaattaata gcttttattg tataaactat cagtttgtcc tgtagaggtt 2550

 ttgttgtttt attttttatt gttttcatct gttgttttgt tttaaatacg 2600

 cactacatgt ggtttataga gggccaagac ttggcaacag aagcagttga 2650

 gtcgtcatca cttttcagtg atgggagagt agatggtgaa atttattagt 2700

 taatatatcc cagaaattag aaaccttaat atgtggacgt aatctccaca 2750

 gtcaaagaag gatggcacct aaaccaccag tgcccaaagt ctgtgtgatg 2800

 aactttctct tcatactttt tttcacagtt ggctggatga aattttctag 2850

 actttctgtt ggtgtatccc ccccctgtat agttaggata gcatttttga 2900

 tttatgcatg gaaacctgaa aaaaagttta caagtgtata tcagaaaagg 2950

 gaagttgtgc cttttatagc tattactgtc tggttttaac aatttccttt 3000

 atatttagtg aactacgctt gctcattttt tcttacataa ttttttattc 3050

 aagttattgt acagctgttt aagatgggca gctagttcgt agctttccca 3100

 aataaactct aaacattaat caatcatctg tgtgaaaatg ggttggtgct 3150

 tctaacctga tggcacttag ctatcagaag accacaaaaa ttgactcaaa 3200

 tctccagtat tcttgtcaaa aaaaaaaaaa aaaaagctca tattttgtat 3250

 atatctgctt cagtggagaa ttatataggt tgtgcaaatt aacagtccta 3300

 actggtatag agcacctagt ccagtgacct gctgggtaaa ctgtggatga 3350

 tggttgcaaa agactaattt aaaaaataac taccaagagg ccctgtctgt 3400

 acctaacgcc ctatttttgc aatggctata tggcaagaaa gctggtaaac 3450

 tatttgtctt tcaggacctt ttgaagtagt ttgtataact tcttaaaagt 3500

 tgtgattcca gataaccagc tgtaacacag ctgagagact tttaatcaga 3550

 caaagtaatt cctctcacta aactttaccc aaaaactaaa tctctaatat 3600

 ggcaaaaatg gctagacacc cattttcaca ttcccatctg tcaccaattg 3650

 gttaatcttt cctgatggta caggaaagct cagctactga tttttgtgat 3700

 ttagaactgt atgtcagaca tccatgtttg taaaactaca catccctaat 3750

 gtgtgccata gagtttaaca caagtcctgt gaatttcttc actgttgaaa 3800

 attattttaa acaaaataga agctgtagta gccctttctg tgtgcacctt 3850

 accaactttc tgtaaactca aaacttaaca tatttactaa gccacaagaa 3900

 atttgatttc tattcaaggt ggccaaatta tttgtgtaat agaaaactga 3950

 aaatctaata ttaaaaatat ggaacttcta atatattttt atatttagtt 4000

 atagtttcag atatatatca tattggtatt cactaatctg ggaagggaag 4050

 ggctactgca gctttacatg caatttatta aaatgattgt aaaatagctt 4100

 gtatagtgta aaataagaat gatttttaga tgagattgtt ttatcatgac 4150

 atgttatata ttttttgtag gggtcaaaga aatgctgatg gataacctat 4200

 atgatttata gtttgtacat gcattcatac aggcagcgat ggtctcagaa 4250

 accaaacagt ttgctctagg ggaagaggga gatggagact ggtcctgtgt 4300

 gcagtgaagg ttgctgaggc tctgacccag tgagattaca gaggaagtta 4350

 tcctctgcct cccattctga ccacccttct cattccaaca gtgagtctgt 4400

 cagcgcaggt ttagtttact caatctcccc ttgcactaaa gtatgtaaag 4450

 tatgtaaaca ggagacagga aggtggtgct tacatcctta aaggcaccat 4500

 ctaatagcgg gttactttca catacagccc tcccccagca gttgaatgac 4550

 aacagaagct tcagaagttt ggcaatagtt tgcatagagg taccagcaat 4600

 atgtaaatag tgcagaatct cataggttgc caataataca ctaattcctt 4650

 tctatcctac aacaagagtt tatttccaaa taaaatgagg acatgttttt 4700

 gttttctttg aatgcttttt gaatgttatt tgttattttc agtattttgg 4750

 agaaattatt taataaaaaa acaatcattt gctttttg 4788

<210> 2414
<211> 777
<212> PRT
<213> Homo sapien

<400> 2414
 Met Asp Ser Lys Glu Ser Leu Thr Pro Gly Arg Glu Glu Asn Pro
   1               5                  10                  15

 Ser Ser Val Leu Ala Gln Glu Arg Gly Asp Val Met Asp Phe Tyr
                  20                  25                  30

 Lys Thr Leu Arg Gly Gly Ala Thr Val Lys Val Ser Ala Ser Ser
                  35                  40                  45

 Pro Ser Leu Ala Val Ala Ser Gln Ser Asp Ser Lys Gln Arg Arg
                  50                  55                  60

 Leu Leu Val Asp Phe Pro Lys Gly Ser Val Ser Asn Ala Gln Gln
                  65                  70                  75

 Pro Asp Leu Ser Lys Ala Val Ser Leu Ser Met Gly Leu Tyr Met
                  80                  85                  90

 Gly Glu Thr Glu Thr Lys Val Met Gly Asn Asp Leu Gly Phe Pro
                  95                 100                 105

 Gln Gln Gly Gln Ile Ser Leu Ser Ser Gly Glu Thr Asp Leu Lys
                 110                 115                 120

 Leu Leu Glu Glu Ser Ile Ala Asn Leu Asn Arg Ser Thr Ser Val
                 125                 130                 135

 Pro Glu Asn Pro Lys Ser Ser Ala Ser Thr Ala Val Ser Ala Ala
                 140                 145                 150

 Pro Thr Glu Lys Glu Phe Pro Lys Thr His Ser Asp Val Ser Ser
                 155                 160                 165

 Glu Gln Gln His Leu Lys Gly Gln Thr Gly Thr Asn Gly Gly Asn
                 170                 175                 180

 Val Lys Leu Tyr Thr Thr Asp Gln Ser Thr Phe Asp Ile Leu Gln
                 185                 190                 195

 Asp Leu Glu Phe Ser Ser Gly Ser Pro Gly Lys Glu Thr Asn Glu
                 200                 205                 210

 Ser Pro Trp Arg Ser Asp Leu Leu Ile Asp Glu Asn Cys Leu Leu
                 215                 220                 225

 Ser Pro Leu Ala Gly Glu Asp Asp Ser Phe Leu Leu Glu Gly Asn
                 230                 235                 240

 Ser Asn Glu Asp Cys Lys Pro Leu Ile Leu Pro Asp Thr Lys Pro
                 245                 250                 255

 Lys Ile Lys Asp Asn Gly Asp Leu Val Leu Ser Ser Pro Ser Asn
                 260                 265                 270

 Val Thr Leu Pro Gln Val Lys Thr Glu Lys Glu Asp Phe Ile Glu
                 275                 280                 285

 Leu Cys Thr Pro Gly Val Ile Lys Gln Glu Lys Leu Gly Thr Val
                 290                 295                 300

 Tyr Cys Gln Ala Ser Phe Pro Gly Ala Asn Ile Ile Gly Asn Lys
                 305                 310                 315

 Met Ser Ala Ile Ser Val His Gly Val Ser Thr Ser Gly Gly Gln
                 320                 325                 330

 Met Tyr His Tyr Asp Met Asn Thr Ala Ser Leu Ser Gln Gln Gln
                 335                 340                 345

 Asp Gln Lys Pro Ile Phe Asn Val Ile Pro Pro Ile Pro Val Gly
                 350                 355                 360

 Ser Glu Asn Trp Asn Arg Cys Gln Gly Ser Gly Asp Asp Asn Leu
                 365                 370                 375

 Thr Ser Leu Gly Thr Leu Asn Phe Pro Gly Arg Thr Val Phe Ser
                 380                 385                 390

 Asn Gly Tyr Ser Ser Pro Ser Met Arg Pro Asp Val Ser Ser Pro
                 395                 400                 405

 Pro Ser Ser Ser Ser Thr Ala Thr Thr Gly Pro Pro Pro Lys Leu
                 410                 415                 420

 Cys Leu Val Cys Ser Asp Glu Ala Ser Gly Cys His Tyr Gly Val
                 425                 430                 435

 Leu Thr Cys Gly Ser Cys Lys Val Phe Phe Lys Arg Ala Val Glu
                 440                 445                 450

 Gly Gln His Asn Tyr Leu Cys Ala Gly Arg Asn Asp Cys Ile Ile
                 455                 460                 465

 Asp Lys Ile Arg Arg Lys Asn Cys Pro Ala Cys Arg Tyr Arg Lys
                 470                 475                 480

 Cys Leu Gln Ala Gly Met Asn Leu Glu Ala Arg Lys Thr Lys Lys
                 485                 490                 495

 Lys Ile Lys Gly Ile Gln Gln Ala Thr Thr Gly Val Ser Gln Glu
                 500                 505                 510

 Thr Ser Glu Asn Pro Gly Asn Lys Thr Ile Val Pro Ala Thr Leu
                 515                 520                 525

 Pro Gln Leu Thr Pro Thr Leu Val Ser Leu Leu Glu Val Ile Glu
                 530                 535                 540

 Pro Glu Val Leu Tyr Ala Gly Tyr Asp Ser Ser Val Pro Asp Ser
                 545                 550                 555

 Thr Trp Arg Ile Met Thr Thr Leu Asn Met Leu Gly Gly Arg Gln
                 560                 565                 570

 Val Ile Ala Ala Val Lys Trp Ala Lys Ala Ile Pro Gly Phe Arg
                 575                 580                 585

 Asn Leu His Leu Asp Asp Gln Met Thr Leu Leu Gln Tyr Ser Trp
                 590                 595                 600

 Met Phe Leu Met Ala Phe Ala Leu Gly Trp Arg Ser Tyr Arg Gln
                 605                 610                 615

 Ser Ser Ala Asn Leu Leu Cys Phe Ala Pro Asp Leu Ile Ile Asn
                 620                 625                 630

 Glu Gln Arg Met Thr Leu Pro Cys Met Tyr Asp Gln Cys Lys His
                 635                 640                 645

 Met Leu Tyr Val Ser Ser Glu Leu His Arg Leu Gln Val Ser Tyr
                 650                 655                 660

 Glu Glu Tyr Leu Cys Met Lys Thr Leu Leu Leu Leu Ser Ser Val
                 665                 670                 675

 Pro Lys Asp Gly Leu Lys Ser Gln Glu Leu Phe Asp Glu Ile Arg
                 680                 685                 690

 Met Thr Tyr Ile Lys Glu Leu Gly Lys Ala Ile Val Lys Arg Glu
                 695                 700                 705

 Gly Asn Ser Ser Gln Asn Trp Gln Arg Phe Tyr Gln Leu Thr Lys
                 710                 715                 720

 Leu Leu Asp Ser Met His Glu Val Val Glu Asn Leu Leu Asn Tyr
                 725                 730                 735

 Cys Phe Gln Thr Phe Leu Asp Lys Thr Met Ser Ile Glu Phe Pro
                 740                 745                 750

 Glu Met Leu Ala Glu Ile Ile Thr Asn Gln Ile Pro Lys Tyr Ser
                 755                 760                 765

 Asn Gly Asn Ile Lys Lys Leu Leu Phe His Gln Lys
                 770                 775

<210> 2415
<211> 4152
<212> DNA
<213> Homo sapien

<400> 2415
 cccaggccgg ctctggcctc ctgacccaga cagcgcaggg cgcgagggat 50

 cgcgcggccg agcccgggtc gcgccgctcc cagcatcggg gccgctagcc 100

 aagagttcga ggccttcccg atccggatgt gatgaaaaag agcaacagag 150

 ggagaagtgt ttcaggattg taggagtgga agaggggaaa gagaggcaga 200

 gagggggaag gccccctcgc aggggagccg gctggagtga gctggctgga 250

 aagagggggc ggagtgcgcg gagtcagagc cgccaccgct gccgcagttg 300

 ccgccactgc ggcgtctggg ctgagccgga gggaggcggg aggacgcgca 350

 ggggcggccg ccgccgtcgt caggccaccg gggcgaaaat gcggccgctg 400

 ccggaggctc gctaactttc cggggcggaa gaggaggagg aggaggagga 450

 aggggcttgg agcgactacg gggggatgcg gagaagcagt cagttccctg 500

 cacccagcac ctcacagccc ttcctccgtg cgccctgccg ggcggcgagc 550

 taggcggcag cggcgcggcg cgggctcggc ggagcggccc atgtccggcg 600

 cgggcgaagc cctcgctccc gggcccgtgg ggccgcagcg cgtggccgag 650

 gcgggcggcg gccagctggg ctccacagcc cagggaaaat gtgataaaga 700

 caatactgag aaagatataa ctcaagctac caatagccac ttcacacatg 750

 gagagatgca agaccagtcc atttggggaa atccttcgga tggtgaactc 800

 attagaaccc aacctcagcg cttgcctcag cttcagactt cagcacaggt 850

 gccaagtggt gaggaaatag gcaagataaa gaacggccac acaggtctga 900

 gcaatggaaa tggaattcac cacggggcca aacacggatc cgcagataat 950

 cgcaaacttt cagcacctgt ttctcaaaaa atgcatagaa aaattcagtc 1000

 cagcttgtct gtaaacagcg atatcagtaa gaagagcaaa gtaaatgctg 1050

 tcttttccca aaagacaggc tcttcacctg aagattgttg tgtccactgt 1100

 atcctggctt gcttgttctg cgaattcctg accctttgca acattgtcct 1150

 gggacaagcg tcatgtggca tctgcacctc agaagcctgc tgctgttgct 1200

 gtggtgacga gatgggggat gattgtaact gcccttgtga tatggactgt 1250

 ggcatcatgg atgcctgttg tgaatcatca gactgcttgg aaatctgtat 1300

 ggaatgctgt ggaatttgtt ttccttcata aatatttatc ttttgtttgt 1350

 gttaaaactg gagagtgttt aaaaatttcc ttttgggggg aagaaaagca 1400

 cattgtaaga ttctcatgaa acaacatgga atttgcactg ttaactcatt 1450

 attgtaagta atctctgaaa gcctttttac tttaaccaaa tctacatggt 1500

 ttaatatgtg aaattttaac tactttaact agttttataa atttcttaat 1550

 atgttacaat aacttaggga cattttgaca ccccccttcc caaatgttaa 1600

 atgccttctc ctttttaccg atatttctgt ttcttttaac cgttctcagg 1650

 agcactttgc tccaaatata ttatttttca gtgtgtattt aaacgaggca 1700

 gtttattttg atatgtatct attcatgatt gaaaggaagc agtcttggcc 1750

 aggcacggtg gcttacacct gtaaccctgg cattttggga ggccaaggtg 1800

 ggcagattgc ctgagctcag gagttcgaga ccagccaggg caacatggtg 1850

 aaaccccatc tctactaaaa tacaaaaagt tagctgggct tggcggtgtg 1900

 cgcctgtagt cccagctact caggaggctg aggcaggaga attgcttgaa 1950

 cccgagaggc ggaagttgca gtgagccgag attgtgccac tgaactccaa 2000

 cctgcactcc agcctgggca acagagcgag actccatctc taaataaata 2050

 aataaataaa taaataaata aataaataaa taaataaaca aaccagtctt 2100

 tattttaaaa gaaactttag gaaacaaacc cacataatag ttgggaacca 2150

 gtgttgatct ctctccctta ccttctccac ttgttcaaca gactctgaat 2200

 gccgactgtg tggactctct tcctcagact gtggggacag atacaattcc 2250

 actcctgtcc acaggaacat gagatttagc agactaagga gatctgtaaa 2300

 gaatgaacca taccacaagg catactgaag tgaggattat aagagaaata 2350

 aactcaaaat gctgttggaa tatgcagaga attgctacca gaatattcag 2400

 taaggtttca gggagaatgt ggcatttgag gactctctta gaatgagtga 2450

 ttcacctgct atttaaatga attatttaga tttttgacaa agatttaggt 2500

 ggacacccta aactgtgtgt gcctttaacc agttaaaaga acagtgcctt 2550

 cagcatactt ttttattagt tgtaggaata cagctttttg aaaaagctat 2600

 aaagtttaaa ttaactaaaa atatgcattt tcttacacat aatttaaatg 2650

 ttatcatact tttttgatga aaacataatg ccttagtaaa atagctctat 2700

 ttaataaaga agattgagta ctctgacaca tttcatttaa attaggaaat 2750

 ttttaatatt aaaatcccag tgttctgagt tattgaaagg ctttctttta 2800

 ttttgagagc tttaggtctt tttgggatga gaacatttta gttgtttagt 2850

 ttgtttctta agcagtgcta ttttttgtaa acacagataa atggaaacca 2900

 ttcttttcaa tgcagaagaa atctagatat cccctactgt gaccaaattt 2950

 ctgtattacg attttatgtt aaattaaact aatatggcag gttataatga 3000

 tccttaagtg taaagaaatc agtcaattac aagagtaatt gtatagttat 3050

 tgagacctat agtgtgtggc ttagatgaaa gggagagtaa attttcatac 3100

 catgctctct cctactcagt ttgatctctc taaaattgta gtttggtttg 3150

 atttaatata attcttagta gaaattttga aagtatgctt tgggattaat 3200

 aattattttt aatttttctg gctgaatatc aaattgatag taacaacaga 3250

 agcataattt taggaaggct ttcgcaaacc tagcctttta agagaggttt 3300

 ttaacctgaa gcatgagaat atatcacctg tggtttttcc tttgagatga 3350

 aacgtagttt ctagttatat cattacttaa agggcttaaa aagaaaaaac 3400

 ttagcaaact tttgaatctt tcttttattg ctatttacac atacatacac 3450

 acatacaaaa cctttaaatt ttgggatctg aatataattc tggtaaacag 3500

 ctgtcttcat ttttctcctc taaagaactt aattcatttg ttacataaaa 3550

 tataaggaaa tctttatact attttacagt aaccacaatc taaatattta 3600

 catataccca aaattaactt atgctcatat attaggatgt gagaatatca 3650

 tctgtttatg gacacatgaa acctcctaat gacctggaat tgttagaata 3700

 tttgactttt tatatgcaaa gtttttcaac caagtggttt gtctaatatt 3750

 taaacatgta ctggcacaat ttgtgatgaa aatattagca catttgcaat 3800

 aatgtttctc cataacagag aatgttaatg gataccagaa ttttattttt 3850

 gtatttatgt tcatagtact tttcctcttg tctactccag acagttattc 3900

 cataaagcat ttgtataatt aaaaggaaaa cagaaaaagg aaaagtaggc 3950

 aaatgtgaaa atagtttcaa tatatcttat gatttcttaa tgtaaaatgt 4000

 tttgttgaag tatatggcta tcatgactaa gtgctagaat ttatagttac 4050

 aggcggtgtc cttttaaatg tggaaaggct tttaaaatat tttaaaactg 4100

 gacctgtatt atcctgaata cactattttg aaaattttta agaaaaaaaa 4150

 aa 4152

<210> 2416
<211> 355
<212> PRT
<213> Homo sapien

<400> 2416
 Val Arg Gly Val Arg Ala Ala Thr Ala Ala Ala Val Ala Ala Thr
   1               5                  10                  15

 Ala Ala Ser Gly Leu Ser Arg Arg Glu Ala Gly Gly Arg Ala Gly
                  20                  25                  30

 Ala Ala Ala Ala Val Val Arg Pro Pro Gly Arg Lys Cys Gly Arg
                  35                  40                  45

 Cys Arg Arg Leu Ala Asn Phe Pro Gly Arg Lys Arg Arg Arg Arg
                  50                  55                  60

 Arg Arg Lys Gly Leu Gly Ala Thr Thr Gly Gly Cys Gly Glu Ala
                  65                  70                  75

 Val Ser Ser Leu His Pro Ala Pro His Ser Pro Ser Ser Val Arg
                  80                  85                  90

 Pro Ala Gly Arg Arg Ala Arg Arg Gln Arg Arg Gly Ala Gly Ser
                  95                 100                 105

 Ala Glu Arg Pro Met Ser Gly Ala Gly Glu Ala Leu Ala Pro Gly
                 110                 115                 120

 Pro Val Gly Pro Gln Arg Val Ala Glu Ala Gly Gly Gly Gln Leu
                 125                 130                 135

 Gly Ser Thr Ala Gln Gly Lys Cys Asp Lys Asp Asn Thr Glu Lys
                 140                 145                 150

 Asp Ile Thr Gln Ala Thr Asn Ser His Phe Thr His Gly Glu Met
                 155                 160                 165

 Gln Asp Gln Ser Ile Trp Gly Asn Pro Ser Asp Gly Glu Leu Ile
                 170                 175                 180

 Arg Thr Gln Pro Gln Arg Leu Pro Gln Leu Gln Thr Ser Ala Gln
                 185                 190                 195

 Val Pro Ser Gly Glu Glu Ile Gly Lys Ile Lys Asn Gly His Thr
                 200                 205                 210

 Gly Leu Ser Asn Gly Asn Gly Ile His His Gly Ala Lys His Gly
                 215                 220                 225

 Ser Ala Asp Asn Arg Lys Leu Ser Ala Pro Val Ser Gln Lys Met
                 230                 235                 240

 His Arg Lys Ile Gln Ser Ser Leu Ser Val Asn Ser Asp Ile Ser
                 245                 250                 255

 Lys Lys Ser Lys Val Asn Ala Val Phe Ser Gln Lys Thr Gly Ser
                 260                 265                 270

 Ser Pro Glu Asp Cys Cys Val His Cys Ile Leu Ala Cys Leu Phe
                 275                 280                 285

 Cys Glu Phe Leu Thr Leu Cys Asn Ile Val Leu Gly Gln Ala Ser
                 290                 295                 300

 Cys Gly Ile Cys Thr Ser Glu Ala Cys Cys Cys Cys Cys Gly Asp
                 305                 310                 315

 Glu Met Gly Asp Asp Cys Asn Cys Pro Cys Asp Met Asp Cys Gly
                 320                 325                 330

 Ile Met Asp Ala Cys Cys Glu Ser Ser Asp Cys Leu Glu Ile Cys
                 335                 340                 345

 Met Glu Cys Cys Gly Ile Cys Phe Pro Ser
                 350                 355

<210> 2417
<211> 2059
<212> DNA
<213> Homo sapien

<400> 2417
 ccgcaggcgc tcggggttgg agccagcgac cgtcggtagc agcatggctc 50

 tcctctttct cctacccctt gtcatgcagg gtgtgagcag ggctgagatg 100

 ggcaccgcgg atctggggcc gtcctcagtg cctacaccaa ctaatgttac 150

 aattgaatcc tataacatga accctatcgt atattgggag taccagatca 200

 tgccacaggt ccctgttttt accgtagagg taaagaacta tggtgttaag 250

 aattcagaat ggattgatgc ctgcatcaat atttctcatc attattgtaa 300

 tatttctgat catgttggtg atccatcaaa ttctctttgg gtcagagtta 350

 aagccagggt tggacaaaaa gaatctgcct atgcaaagtc agaagaattt 400

 gctgtatgcc gagatggaaa aattggacca cctaaactgg atatcagaaa 450

 ggaggagaag caaatcatga ttgacatatt tcacccttca gtttttgtaa 500

 atggagacga gcaggaagtc gattatgatc ccgaaactac ctgttacatt 550

 agggtgtaca atgtgtatgt gagaatgaac ggaagtgaga tccagtataa 600

 aatactcacg cagaaggaag atgattgtga cgagattcag tgccagttag 650

 cgattccagt atcctcactg aattctcagt actgtgtttc agcagaagga 700

 gtcttacatg tgtggggtgt tacaactgaa aagtcaaaag aagtttgtat 750

 taccattttc aatagcagta taaaaggttc tctttggatt ccagttgttg 800

 ctgctttact actctttcta gtgcttagcc tggtattcat ctgtttttat 850

 attaagaaaa ttaatccatt gaaggaaaaa agcataatat tacccaagtc 900

 cttgatctct gtggtaagaa gtgctacttt agagacaaaa cctgaatcaa 950

 aatatgtatc actcatcacg tcataccagc cattttcctt agaaaaggag 1000

 gtggtctgtg aagagccgtt gtctccagca acagttccag gcatgcatac 1050

 cgaagacaat ccaggaaaag tggaacatac agaagaactt tctagtataa 1100

 cagaagtggt gactactgaa gaaaatattc ctgacgtggt cccgggcagc 1150

 catctgactc caatagagag agagagttct tcacctttaa gtagtaacca 1200

 gtctgaacct ggcagcatcg ctttaaactc gtatcactcc agaaattgtt 1250

 ctgagagtga tcactccaga aatggttttg atactgattc cagctgtctg 1300

 gaatcacata gctccttatc tgactcagaa tttcccccaa ataataaagg 1350

 tgaaataaaa acagaaggac aagagctcat aaccgtaata aaagccccca 1400

 cctcctttgg ttatgataaa ccacatgtgc tagtggatct acttgtggat 1450

 gatagcggta aagagtcctt gattggttat agaccaacag aagattccaa 1500

 agaattttca tgagatcagc taagttgcac caactttgaa gtctgatttt 1550

 cctggacagt tttctgcttt aatttcatga aaagattatg atctcagaaa 1600

 ttgtatctta gttggtatca accaaatgga gtgacttagt gtacatgaaa 1650

 gcgtaaagag gatgtgtggc attttcactt ttggcttgta aagtacagac 1700

 tttttttttt ttttaaacaa aaaaagcatt gtaacttatg aacctttaca 1750

 tccagatagg ttaccagtaa cggaacatat ccagtactcc tggttcctag 1800

 gtgagcaggt gatgccccag ggacctttgt agccacttca ctttttttct 1850

 tttctctgcc ttggtatagc atatgtgttt tgtaagttta tgcatacagt 1900

 aattttaagt aatttcagaa gaaattctcg aagcttttca aaattggact 1950

 taaaatctaa ttcaaactaa tagaattaat ggaatatgta aatagaaacg 2000

 tgtatatttt ttatgaaaca ttacagttag agatttttaa ataaagaatt 2050

 ttaaaactc 2059

<210> 2418
<211> 489
<212> PRT
<213> Homo sapien

<400> 2418
 Met Ala Leu Leu Phe Leu Leu Pro Leu Val Met Gln Gly Val Ser
   1               5                  10                  15

 Arg Ala Glu Met Gly Thr Ala Asp Leu Gly Pro Ser Ser Val Pro
                  20                  25                  30

 Thr Pro Thr Asn Val Thr Ile Glu Ser Tyr Asn Met Asn Pro Ile
                  35                  40                  45

 Val Tyr Trp Glu Tyr Gln Ile Met Pro Gln Val Pro Val Phe Thr
                  50                  55                  60

 Val Glu Val Lys Asn Tyr Gly Val Lys Asn Ser Glu Trp Ile Asp
                  65                  70                  75

 Ala Cys Ile Asn Ile Ser His His Tyr Cys Asn Ile Ser Asp His
                  80                  85                  90

 Val Gly Asp Pro Ser Asn Ser Leu Trp Val Arg Val Lys Ala Arg
                  95                 100                 105

 Val Gly Gln Lys Glu Ser Ala Tyr Ala Lys Ser Glu Glu Phe Ala
                 110                 115                 120

 Val Cys Arg Asp Gly Lys Ile Gly Pro Pro Lys Leu Asp Ile Arg
                 125                 130                 135

 Lys Glu Glu Lys Gln Ile Met Ile Asp Ile Phe His Pro Ser Val
                 140                 145                 150

 Phe Val Asn Gly Asp Glu Gln Glu Val Asp Tyr Asp Pro Glu Thr
                 155                 160                 165

 Thr Cys Tyr Ile Arg Val Tyr Asn Val Tyr Val Arg Met Asn Gly
                 170                 175                 180

 Ser Glu Ile Gln Tyr Lys Ile Leu Thr Gln Lys Glu Asp Asp Cys
                 185                 190                 195

 Asp Glu Ile Gln Cys Gln Leu Ala Ile Pro Val Ser Ser Leu Asn
                 200                 205                 210

 Ser Gln Tyr Cys Val Ser Ala Glu Gly Val Leu His Val Trp Gly
                 215                 220                 225

 Val Thr Thr Glu Lys Ser Lys Glu Val Cys Ile Thr Ile Phe Asn
                 230                 235                 240

 Ser Ser Ile Lys Gly Ser Leu Trp Ile Pro Val Val Ala Ala Leu
                 245                 250                 255

 Leu Leu Phe Leu Val Leu Ser Leu Val Phe Ile Cys Phe Tyr Ile
                 260                 265                 270

 Lys Lys Ile Asn Pro Leu Lys Glu Lys Ser Ile Ile Leu Pro Lys
                 275                 280                 285

 Ser Leu Ile Ser Val Val Arg Ser Ala Thr Leu Glu Thr Lys Pro
                 290                 295                 300

 Glu Ser Lys Tyr Val Ser Leu Ile Thr Ser Tyr Gln Pro Phe Ser
                 305                 310                 315

 Leu Glu Lys Glu Val Val Cys Glu Glu Pro Leu Ser Pro Ala Thr
                 320                 325                 330

 Val Pro Gly Met His Thr Glu Asp Asn Pro Gly Lys Val Glu His
                 335                 340                 345

 Thr Glu Glu Leu Ser Ser Ile Thr Glu Val Val Thr Thr Glu Glu
                 350                 355                 360

 Asn Ile Pro Asp Val Val Pro Gly Ser His Leu Thr Pro Ile Glu
                 365                 370                 375

 Arg Glu Ser Ser Ser Pro Leu Ser Ser Asn Gln Ser Glu Pro Gly
                 380                 385                 390

 Ser Ile Ala Leu Asn Ser Tyr His Ser Arg Asn Cys Ser Glu Ser
                 395                 400                 405

 Asp His Ser Arg Asn Gly Phe Asp Thr Asp Ser Ser Cys Leu Glu
                 410                 415                 420

 Ser His Ser Ser Leu Ser Asp Ser Glu Phe Pro Pro Asn Asn Lys
                 425                 430                 435

 Gly Glu Ile Lys Thr Glu Gly Gln Glu Leu Ile Thr Val Ile Lys
                 440                 445                 450

 Ala Pro Thr Ser Phe Gly Tyr Asp Lys Pro His Val Leu Val Asp
                 455                 460                 465

 Leu Leu Val Asp Asp Ser Gly Lys Glu Ser Leu Ile Gly Tyr Arg
                 470                 475                 480

 Pro Thr Glu Asp Ser Lys Glu Phe Ser
                 485

<210> 2419
<211> 3300
<212> DNA
<213> Homo sapien

<400> 2419
 ggggagaatc tggtggatgc tggaccttgc tgctgctgct actgctgttt 50

 ccaggggctg cagagcatgg actgttaaat cttgcacttc ttctgagtga 100

 gctgaattct tgccgccagg atggggaaac agaacagcaa gctgcgcccg 150

 gaggtcatgc aggacttgct ggaaagcaca gactttacag agcatgagat 200

 ccaggaatgg tataaaggct tcttgagaga ctgccccagt ggacatttgt 250

 caatggaaga gtttaagaaa atatatggga actttttccc ttatggggat 300

 gcttccaaat ttgcagagca tgtcttccgc accttcgatg caaatggaga 350

 tgggacaata gactttagag aattcatcat cgccttgagt gtaacttcga 400

 gggggaagct ggagcagaag ctgaaatggg ccttcagcat gtacgacctg 450

 gacggaaatg gctatatcag caaggcagag atgctagtga tcgtgcaggc 500

 aatctataag atggtttcct ctgtaatgaa aatgcctgaa gatgagtcaa 550

 ccccagagaa aagaacagaa aagatcttcc gccagatgga caccaataga 600

 gacggaaaac tctccctgga agagttcatc cgaggagcca aaagcgaccc 650

 gtccattgtg cgcctcctgc agtgcgaccc gagcagtgcc ggccagttct 700

 gagccctgcg cccaccaatc gaattgtaga gctgcttgtg ttcccttttg 750

 attcttcttt ttaacaattt tttttttttt ttgccaaaca atatcaatgg 800

 tgatgccgtc ccctgtgcgg tctgatgcgc cttcctccgt gacgccttca 850

 gcctcttttg tcgtggatgc ttcgtgggaa tgcccagagc cccagtgtgc 900

 ttgtggagag catggacaga cttcgtggtg ttcattgttt gatgattttt 950

 aatcgttact attatttctt tttattctaa tgtctctgtt ctaaaacgta 1000

 agactcgggg gttggggcaa aagaagggaa acccatccag tcctgtgatt 1050

 ctattgcaag cttcaagggg cttttgtttg aaagacaaaa ctccccacct 1100

 gggtctgttg tcacacgtgc cgtaggggtg atggatggca ccggatgctg 1150

 gattccccaa gaacaagtta ccctctgggg tgaggctatt ccagcgagct 1200

 gggacatttc cccatggggg cccactcccc tctcttcccc agcaggctgt 1250

 agtttctaag ctgtgaacat ttcaagataa attaacagag gagaggaaaa 1300

 agatggctca gctatttttt cacaggttta cactagttga gctaatatgc 1350

 gtgtctttgg aaattaaaca caaatggtaa catattccaa aaccagaccc 1400

 atcttgttgc ctattgtgat aaaataaaaa gacggctgta tataacatat 1450

 tgggtaatgc agaccaaatt aagtgttttg ccttgtttaa atgaaatgca 1500

 tgtttagtga gcactaatac aatcttattc cagaagactg tttttagtag 1550

 cttattgtga agtaagacaa ctataatgaa tgtctgtctt gtttggaagt 1600

 catatctgtc tttgcacaaa tgtaccaatc gacaagtata ttttatatat 1650

 tccataaaaa tacaaagtaa ccctgactag ggcccaactt taattttgaa 1700

 tgcatttcca gagtggccat gcctagaggg cagatgcaga gcaggtggta 1750

 gtgggacagg acaattggag cacaggaatg ttaacatgta tgacagggga 1800

 ccagtagggt ggtttccctc tcaggcccag cagcccattg acagcattag 1850

 actggcggca tggtgctttt ctgagcagat caatactctg cagactcgaa 1900

 aaaacatcac atacattctt ggaacttccc agtggtttaa tctatgtgca 1950

 tggttaggga gccaggcctg gaatattcag tttccctgcc cctgttaaag 2000

 aatcagaggt tgggcagtca tcaaattcat cataaagaca tgggcaagtg 2050

 tgtctgtggt ttccaaggcc cccctatgga gaatccaaaa gtattttcca 2100

 ttgccgtgct ctttgaatgc agacttctat ttccagaagt gacagcacaa 2150

 gtctgagttg ctgtttggtc tggtgacctc agacacacta atttgaattg 2200

 aaagctaaga gtaaaaattt gctggttaca ggcgagtcat actcttgcaa 2250

 gtagttagca aagggaggcc caaattctca aggttgttga tggggaactt 2300

 gccactaaga gaaggcagag aggtccctag tgggtatatt tgctgccaag 2350

 ccacttgcca aagaagagga accacagaaa gagagacatc atgaccagga 2400

 gaaaaatgtg actagacatg ctaacctcca ggtttttata tatgacttga 2450

 gtctgctgta attggcagca gaaatccaaa tttgtatggt agaccaaaaa 2500

 gaaccaaatc catagggtga aattttgaga cctagactct gtaaaaataa 2550

 tcctagtctt cctccagggg tcagttcctc acagtggttc tgtaccaaaa 2600

 cttgccaaat tcctccatgg ccaagtgtta aaatctgtgt ttggaaaata 2650

 gcgaattaac ctaagacaca gaaggcagac tgggtgagga gacctagcat 2700

 gccctattgg cagtgctcag gagctgcatc ccacttttcc ctgctctgaa 2750

 tcgaagtcct agttccttcc tttgattctc ctttggtagg tggaatcagt 2800

 taatgttttg agaaacctgc ctgggctctg cccttagtca tgacatctcg 2850

 ctgagccaga cccactctgt tccttggaac ctagagctgg agtgaggagt 2900

 agaggtctcc ggctattcca gaaagaaaag tgagccacat gcaggctgat 2950

 gaatgccgac acttccagaa tgtatagaaa tagtccctgt cctggcctgc 3000

 cactgaccct gtctgtattt tctcggaggt tgtttttctc cttctccttc 3050

 ccaggaaggt ctttgtatgt cgaatccagt gcactcaagt ttggccaagg 3100

 gactccacag cacccagagg actgcatgcc tcaaggttta tgtcactcct 3150

 ctgctgggct gttcattgtc attgctgtgt tcagggacct ttggaaataa 3200

 aacctgttct gtcccaaata aaaccagcct gtgatgttca agggactgga 3250

 ataaagtggc ttacgacctg aaggattcta aaaaaaaaaa aaaaaaaaaa 3300

<210> 2420
<211> 193
<212> PRT
<213> Homo sapien

<400> 2420
 Met Gly Lys Gln Asn Ser Lys Leu Arg Pro Glu Val Met Gln Asp
   1               5                  10                  15

 Leu Leu Glu Ser Thr Asp Phe Thr Glu His Glu Ile Gln Glu Trp
                  20                  25                  30

 Tyr Lys Gly Phe Leu Arg Asp Cys Pro Ser Gly His Leu Ser Met
                  35                  40                  45

 Glu Glu Phe Lys Lys Ile Tyr Gly Asn Phe Phe Pro Tyr Gly Asp
                  50                  55                  60

 Ala Ser Lys Phe Ala Glu His Val Phe Arg Thr Phe Asp Ala Asn
                  65                  70                  75

 Gly Asp Gly Thr Ile Asp Phe Arg Glu Phe Ile Ile Ala Leu Ser
                  80                  85                  90

 Val Thr Ser Arg Gly Lys Leu Glu Gln Lys Leu Lys Trp Ala Phe
                  95                 100                 105

 Ser Met Tyr Asp Leu Asp Gly Asn Gly Tyr Ile Ser Lys Ala Glu
                 110                 115                 120

 Met Leu Val Ile Val Gln Ala Ile Tyr Lys Met Val Ser Ser Val
                 125                 130                 135

 Met Lys Met Pro Glu Asp Glu Ser Thr Pro Glu Lys Arg Thr Glu
                 140                 145                 150

 Lys Ile Phe Arg Gln Met Asp Thr Asn Arg Asp Gly Lys Leu Ser
                 155                 160                 165

 Leu Glu Glu Phe Ile Arg Gly Ala Lys Ser Asp Pro Ser Ile Val
                 170                 175                 180

 Arg Leu Leu Gln Cys Asp Pro Ser Ser Ala Gly Gln Phe
                 185                 190

<210> 2421
<211> 1863
<212> DNA
<213> Homo sapien

<400> 2421
 tgtctgcacc ggcagcacca tgtcgctcac ggtcgtcagc atggcgtgcg 50

 ttgggttctt cttgctgcag ggggcctggc cactcatggg tggtcaggac 100

 aaacccttcc tgtctgcccg gcccagcact gtggtgcctc gaggaggaca 150

 cgtggctctt cagtgtcact atcgtcgtgg gtttaacaat ttcatgctgt 200

 acaaagaaga cagaagccac gttcccatct tccacggcag aatattccag 250

 gagagcttca tcatgggccc tgtgacccca gcacatgcag ggacctacag 300

 atgtcggggt tcacgcccac actccctcac tgggtggtcg gcacccagca 350

 accccctggt gatcatggtc acaggaaacc acagaaaacc ttccctcctg 400

 gcccacccag ggcccctgct gaaatcagga gagacagtca tcctgcaatg 450

 ttggtcagat gtcatgtttg agcacttctt tctgcacaga gaggggatct 500

 ctgaggaccc ctcacgcctc gttggacaga tccatgatgg ggtctccaag 550

 gccaacttct ccatcggtcc cttgatgcct gtccttgcag gaacctacag 600

 atgttatggt tctgttcctc actcccccta tcagttgtca gctcccagtg 650

 accccctgga catcgtgatc acaggtctat atgagaaacc ttctctctca 700

 gcccagccgg gccccacggt tcaggcagga gagaacgtga ccttgtcctg 750

 tagctcctgg agctcctatg acatctacca tctgtccagg gaaggggagg 800

 cccatgaacg taggctccgt gcagtgccca aggtcaacag aacattccag 850

 gcagactttc ctctgggccc tgccacccac ggagggacct acagatgctt 900

 cggctctttc cgtgccctgc cctgcgtgtg gtcaaactca agtgacccac 950

 tgcttgtttc tgtcacagga aacccttcaa gtagttggcc ttcacccaca 1000

 gaaccaagct ccaaatctgg tatctgcaga cacctgcatg ttctgattgg 1050

 gacctcagtg gtcatcttcc tcttcatcct cctcctcttc tttctccttt 1100

 atcgctggtg ctccaacaaa aagaatgctg ctgtaatgga ccaagagcct 1150

 gcgggggaca gaacagtgaa taggcaggac tctgatgaac aagaccctca 1200

 ggaggtgacg tacgcacagt tggatcactg cgttttcata cagagaaaaa 1250

 tcagtcgccc ttctcagagg cccaagacac ccctaacaga taccagcgtg 1300

 tacacggaac ttccaaatgc tgagcccaga tccaaagttg tctcctgccc 1350

 acgagcacca cagtcaggtc ttgagggggt tttctaggga gacaacagcc 1400

 ctgtctcaaa accaggttgc cagatccaat gaaccagcag ctggaatctg 1450

 aaggcatcag tctgcatctt aggggatcgc tcttcctcac accacgaatc 1500

 tgaacatgcc tctctcttgc ttacaaatgc ctaaggtcgc cactgcctgc 1550

 tgcagagaaa acacactcct ttgcttagcc cacaagtatc tatttcactt 1600

 gacccctgcc cacctctcca acctaactgg cttacttcct agtcctactt 1650

 gaggctgcaa tcacactgag gaactcacaa ttccaaacat acaagaggct 1700

 ccctcttaac acggcactta cacacttgct gttccacctt ccctcatgct 1750

 gttccacctc ccctcagact atctttcagc cttctgtcat cagtaaaatt 1800

 tataaatttt ttttataact tcagtgtagc tctctcctct tcaaataaac 1850

 atgtctgccc tca 1863

<210> 2422
<211> 455
<212> PRT
<213> Homo sapien

<400> 2422
 Met Ser Leu Thr Val Val Ser Met Ala Cys Val Gly Phe Phe Leu
   1               5                  10                  15

 Leu Gln Gly Ala Trp Pro Leu Met Gly Gly Gln Asp Lys Pro Phe
                  20                  25                  30

 Leu Ser Ala Arg Pro Ser Thr Val Val Pro Arg Gly Gly His Val
                  35                  40                  45

 Ala Leu Gln Cys His Tyr Arg Arg Gly Phe Asn Asn Phe Met Leu
                  50                  55                  60

 Tyr Lys Glu Asp Arg Ser His Val Pro Ile Phe His Gly Arg Ile
                  65                  70                  75

 Phe Gln Glu Ser Phe Ile Met Gly Pro Val Thr Pro Ala His Ala
                  80                  85                  90

 Gly Thr Tyr Arg Cys Arg Gly Ser Arg Pro His Ser Leu Thr Gly
                  95                 100                 105

 Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Met Val Thr Gly Asn
                 110                 115                 120

 His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu Leu Lys
                 125                 130                 135

 Ser Gly Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Met Phe
                 140                 145                 150

 Glu His Phe Phe Leu His Arg Glu Gly Ile Ser Glu Asp Pro Ser
                 155                 160                 165

 Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe
                 170                 175                 180

 Ser Ile Gly Pro Leu Met Pro Val Leu Ala Gly Thr Tyr Arg Cys
                 185                 190                 195

 Tyr Gly Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser
                 200                 205                 210

 Asp Pro Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser
                 215                 220                 225

 Leu Ser Ala Gln Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val
                 230                 235                 240

 Thr Leu Ser Cys Ser Ser Trp Ser Ser Tyr Asp Ile Tyr His Leu
                 245                 250                 255

 Ser Arg Glu Gly Glu Ala His Glu Arg Arg Leu Arg Ala Val Pro
                 260                 265                 270

 Lys Val Asn Arg Thr Phe Gln Ala Asp Phe Pro Leu Gly Pro Ala
                 275                 280                 285

 Thr His Gly Gly Thr Tyr Arg Cys Phe Gly Ser Phe Arg Ala Leu
                 290                 295                 300

 Pro Cys Val Trp Ser Asn Ser Ser Asp Pro Leu Leu Val Ser Val
                 305                 310                 315

 Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser Pro Thr Glu Pro Ser
                 320                 325                 330

 Ser Lys Ser Gly Ile Cys Arg His Leu His Val Leu Ile Gly Thr
                 335                 340                 345

 Ser Val Val Ile Phe Leu Phe Ile Leu Leu Leu Phe Phe Leu Leu
                 350                 355                 360

 Tyr Arg Trp Cys Ser Asn Lys Lys Asn Ala Ala Val Met Asp Gln
                 365                 370                 375

 Glu Pro Ala Gly Asp Arg Thr Val Asn Arg Gln Asp Ser Asp Glu
                 380                 385                 390

 Gln Asp Pro Gln Glu Val Thr Tyr Ala Gln Leu Asp His Cys Val
                 395                 400                 405

 Phe Ile Gln Arg Lys Ile Ser Arg Pro Ser Gln Arg Pro Lys Thr
                 410                 415                 420

 Pro Leu Thr Asp Thr Ser Val Tyr Thr Glu Leu Pro Asn Ala Glu
                 425                 430                 435

 Pro Arg Ser Lys Val Val Ser Cys Pro Arg Ala Pro Gln Ser Gly
                 440                 445                 450

 Leu Glu Gly Val Phe
                 455

<210> 2423
<211> 1449
<212> DNA
<213> Homo sapien

<400> 2423
 cttttcctgt ggcagcagcc gggctgagag gagcgtggct gtctcctctc 50

 tccgccatgg cgtgtgctcg cccactgata tcggtgtact ccgaaaaggg 100

 ggagtcatct ggcaaaaatg tcactttgcc tgctgtattc aaggctccta 150

 ttcgaccaga tattgtgaac tttgttcaca ccaacttgcg caaaaacaac 200

 agacagccct atgctgtcag tgaattagca ggtcatcaga ctagtgctga 250

 gtcttggggt actggcagag ctgtggctcg aattcccaga gttcgaggtg 300

 gtgggactca ccgctctggc cagggtgctt ttggaaacat gtgtcgtgga 350

 ggccgaatgt ttgcaccaac caaaacctgg cgccgttggc atcgtagagt 400

 gaacacaacc caaaaacgat acgccatctg ttctgccctg gctgcctcag 450

 ccctaccagc actggtcatg tctaaaggtc atcgtattga ggaagttcct 500

 gaacttcctt tggtagttga agataaagtt gaaggctaca agaagaccaa 550

 ggaagctgtt ttgctcctta agaaacttaa agcctggaat gatatcaaaa 600

 aggtctatgc ctctcagcga atgagagctg gcaaaggcaa aatgagaaac 650

 cgtcgccgta tccagcgcag gggcccgtgc atcatctata atgaggataa 700

 tggtatcatc aaggccttca gaaacatccc tggaattact ctgcttaatg 750

 taagcaagct gaacattttg aagcttgctc ctggtgggca tgtgggacgt 800

 ttctgcattt ggactgaaag tgctttccgg aagttagatg aattgtacgg 850

 cacttggcgt aaagccgctt ccctcaagag taactacaat cttcccatgc 900

 acaagatgat taatacagat cttagcagaa tcttgaaaag cccagagatc 950

 caaagagccc ttcgagcacc acgcaagaag atccatcgca gagtcctaaa 1000

 gaagaaccca ctgaaaaact tgagaatcat gttgaagcta aacccatatg 1050

 caaagaccat gcgccggaac accattcttc gccaggccag gaatcacaag 1100

 ctccgggtgg ataaggcagc tgctgcagca gcggcactac aagccaaatc 1150

 agatgagaag gcggcggttg caggcaagaa gcctgtggta ggtaagaaag 1200

 gaaagaaggc tgctgttggt gttaagaagc agaagaagcc tctggtggga 1250

 aaaaaggcag cagctaccaa gaaaccagcc cctgaaaaga agcctgcaga 1300

 gaagaaacct actacagagg agaagaagcc tgctgcataa actcttaaat 1350

 ttgattattc cataaaggtc aaatcatttt ggacagcttc ttttgaataa 1400

 agacctgatt atacaggcag tgagaaacat gaaaaaaaaa aaaaaaaaa 1449

<210> 2424
<211> 427
<212> PRT
<213> Homo sapien

<400> 2424
 Met Ala Cys Ala Arg Pro Leu Ile Ser Val Tyr Ser Glu Lys Gly
   1               5                  10                  15

 Glu Ser Ser Gly Lys Asn Val Thr Leu Pro Ala Val Phe Lys Ala
                  20                  25                  30

 Pro Ile Arg Pro Asp Ile Val Asn Phe Val His Thr Asn Leu Arg
                  35                  40                  45

 Lys Asn Asn Arg Gln Pro Tyr Ala Val Ser Glu Leu Ala Gly His
                  50                  55                  60

 Gln Thr Ser Ala Glu Ser Trp Gly Thr Gly Arg Ala Val Ala Arg
                  65                  70                  75

 Ile Pro Arg Val Arg Gly Gly Gly Thr His Arg Ser Gly Gln Gly
                  80                  85                  90

 Ala Phe Gly Asn Met Cys Arg Gly Gly Arg Met Phe Ala Pro Thr
                  95                 100                 105

 Lys Thr Trp Arg Arg Trp His Arg Arg Val Asn Thr Thr Gln Lys
                 110                 115                 120

 Arg Tyr Ala Ile Cys Ser Ala Leu Ala Ala Ser Ala Leu Pro Ala
                 125                 130                 135

 Leu Val Met Ser Lys Gly His Arg Ile Glu Glu Val Pro Glu Leu
                 140                 145                 150

 Pro Leu Val Val Glu Asp Lys Val Glu Gly Tyr Lys Lys Thr Lys
                 155                 160                 165

 Glu Ala Val Leu Leu Leu Lys Lys Leu Lys Ala Trp Asn Asp Ile
                 170                 175                 180

 Lys Lys Val Tyr Ala Ser Gln Arg Met Arg Ala Gly Lys Gly Lys
                 185                 190                 195

 Met Arg Asn Arg Arg Arg Ile Gln Arg Arg Gly Pro Cys Ile Ile
                 200                 205                 210

 Tyr Asn Glu Asp Asn Gly Ile Ile Lys Ala Phe Arg Asn Ile Pro
                 215                 220                 225

 Gly Ile Thr Leu Leu Asn Val Ser Lys Leu Asn Ile Leu Lys Leu
                 230                 235                 240

 Ala Pro Gly Gly His Val Gly Arg Phe Cys Ile Trp Thr Glu Ser
                 245                 250                 255

 Ala Phe Arg Lys Leu Asp Glu Leu Tyr Gly Thr Trp Arg Lys Ala
                 260                 265                 270

 Ala Ser Leu Lys Ser Asn Tyr Asn Leu Pro Met His Lys Met Ile
                 275                 280                 285

 Asn Thr Asp Leu Ser Arg Ile Leu Lys Ser Pro Glu Ile Gln Arg
                 290                 295                 300

 Ala Leu Arg Ala Pro Arg Lys Lys Ile His Arg Arg Val Leu Lys
                 305                 310                 315

 Lys Asn Pro Leu Lys Asn Leu Arg Ile Met Leu Lys Leu Asn Pro
                 320                 325                 330

 Tyr Ala Lys Thr Met Arg Arg Asn Thr Ile Leu Arg Gln Ala Arg
                 335                 340                 345

 Asn His Lys Leu Arg Val Asp Lys Ala Ala Ala Ala Ala Ala Ala
                 350                 355                 360

 Leu Gln Ala Lys Ser Asp Glu Lys Ala Ala Val Ala Gly Lys Lys
                 365                 370                 375

 Pro Val Val Gly Lys Lys Gly Lys Lys Ala Ala Val Gly Val Lys
                 380                 385                 390

 Lys Gln Lys Lys Pro Leu Val Gly Lys Lys Ala Ala Ala Thr Lys
                 395                 400                 405

 Lys Pro Ala Pro Glu Lys Lys Pro Ala Glu Lys Lys Pro Thr Thr
                 410                 415                 420

 Glu Glu Lys Lys Pro Ala Ala
                 425

<210> 2425
<211> 2519
<212> DNA
<213> Rattus norvegicus

<400> 2425
 ggcacgaggg cacctcgctg ctccagcctc tggggcgcat tccaaccttc 50

 cagcctgcga cctgcggaga aaaaaaatta cttattttct tgccccatac 100

 ataccttgag gcgagcaaaa aaattaaatt ttaaccatga gggaaatcgt 150

 gcacatccag gctggtcagt gtggcaacca gatcggtgcc aagttctggg 200

 aggtgatcag tgatgaacat ggcatcgacc ccaccggcac ctaccacggg 250

 gacagcgacc tgcagctgga ccgcatctct gtgtactaca atgaagccac 300

 aggtggcaaa tatgttcctc gtgccatcct ggtggatcta gaacctggga 350

 ccatggactc tgttcgctca ggtccttttg gccagatctt tagaccagac 400

 aactttgtat ttggtcagtc tggggcaggt aacaactggg ccaaaggcca 450

 ctacacagag ggcgccgagc tggttgattc tgtcctggat gtggtacgga 500

 aggaggcaga gagctgtgac tgcctgcagg gcttccagct gacccactca 550

 ctgggcgggg gcacaggctc tggaatgggc actctcctta tcagcaagat 600

 ccgagaagaa taccctgatc gcatcatgaa taccttcagt gtggtgcctt 650

 cacccaaagt gtctgacacc gtggtcgagc cctacaatgc caccctctcc 700

 gtccatcagt tggtagagaa tactgatgag acctattgca ttgacaacga 750

 ggccctctat gatatctgct tccgcactct gaagctgacc acaccaacct 800

 acggggatct gaaccacctt gtctcagcca ccatgagtgg tgtcaccacc 850

 tgcctccgtt tccctggcca gctcaatgct gacctccgca agttggcagt 900

 caacatggtc cccttcccac gtctccattt ctttatgcct ggctttgccc 950

 ctctcaccag ccgtggaagc cagcagtatc gagctctcac agtgccggaa 1000

 ctcacccagc aggtcttcga tgccaagaac atgatggctg cctgtgaccc 1050

 ccgccacggc cgatacctca ccgtggctgc tgtcttccgt ggtcggatgt 1100

 ccatgaagga ggtcgatgag cagatgctta acgtgcagaa caagaacagc 1150

 agctactttg tggaatggat ccccaacaat gtcaagacag ccgtctgtga 1200

 catcccacct cgtggcctca agatggcagt caccttcatt ggcaatagca 1250

 cagccatcca ggagctcttc aagcgcatct cggagcagtt cactgccatg 1300

 ttccgccgga aggccttcct ccactggtac acaggcgagg gcatggacga 1350

 gatggagttc accgaggctg agagcaacat gaacgacctc gtctctgagt 1400

 atcagcagta ccaggatgcc accgcagaag aggaggagga tttcggtgag 1450

 gaggccgaag aggaggccta aggcagagcc cccatcacct caggcttctc 1500

 agttccctta gccgtcttac tcaactgccc ctttcctctc cctcagaatt 1550

 tgtgtttgct gcctctatct tgttttttgt tttttcttct ggggggggtc 1600

 tagaacagtg cctggcacat agtaggcgct caataaatac ttgtttgttg 1650

 aatgtctcct ctctctttcc actctgggaa acctaggttt ctgccattct 1700

 gggtgaccct gtatttcttt ctggtgccca ttccatttgt ccagttaata 1750

 cttcctctta aaaatctcca agaagctggg tctccagatc ccatttagaa 1800

 ccaaccaggt gctgaaaaca catgtagata atggccatca tcctaagccc 1850

 aaagtagaaa atggtagaag gtagtgggta gaagtcacta tataaggaag 1900

 gggatgggat tttccattct aaaagttttg gagagggaaa tccaggctat 1950

 taaagtcact aaatttctaa gtatgtccat ttcccatctc agcttcaagg 2000

 gaggtgtcag cagtattatc tccactttca atctccctcc aagctctact 2050

 ctggaggagt ctgtcccact ctgtcaagtg gaatccttcc ctttccaact 2100

 ctacctccct cactcagctc ctttcccctg atcagagaaa gggatcaagg 2150

 gggttgggag gggggaaaga gaccagcctt ggtccctaag cctccagaaa 2200

 cgtcttctta atccccacct tttcttactc ccaaaaaaga atgaacaccc 2250

 ctgactctgg agtggtgtat actgccacat cagtgtttga gtcagtcccc 2300

 agaggagagg ggaaccctcc tccatctttt ttgcaacatc tcatttcttc 2350

 cttttgctgt tgcttccccc ctcacacact tggttttgtt ctatcctaca 2400

 tttgagattt ctattttatg ttgaacttgc tgcttttttt catattgaaa 2450

 agatgacatc gccccaagag ccaaaaataa atgggaattg aaaaaaaaaa 2500

 aaaaaaaaaa aaaaaaaaa 2519

<210> 2426
<211> 444
<212> PRT
<213> Rattus norvegicus

<400> 2426
 Met Arg Glu Ile Val His Ile Gln Ala Gly Gln Cys Gly Asn Gln
   1               5                  10                  15

 Ile Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile
                  20                  25                  30

 Asp Pro Thr Gly Thr Tyr His Gly Asp Ser Asp Leu Gln Leu Asp
                  35                  40                  45

 Arg Ile Ser Val Tyr Tyr Asn Glu Ala Thr Gly Gly Lys Tyr Val
                  50                  55                  60

 Pro Arg Ala Ile Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser
                  65                  70                  75

 Val Arg Ser Gly Pro Phe Gly Gln Ile Phe Arg Pro Asp Asn Phe
                  80                  85                  90

 Val Phe Gly Gln Ser Gly Ala Gly Asn Asn Trp Ala Lys Gly His
                  95                 100                 105

 Tyr Thr Glu Gly Ala Glu Leu Val Asp Ser Val Leu Asp Val Val
                 110                 115                 120

 Arg Lys Glu Ala Glu Ser Cys Asp Cys Leu Gln Gly Phe Gln Leu
                 125                 130                 135

 Thr His Ser Leu Gly Gly Gly Thr Gly Ser Gly Met Gly Thr Leu
                 140                 145                 150

 Leu Ile Ser Lys Ile Arg Glu Glu Tyr Pro Asp Arg Ile Met Asn
                 155                 160                 165

 Thr Phe Ser Val Val Pro Ser Pro Lys Val Ser Asp Thr Val Val
                 170                 175                 180

 Glu Pro Tyr Asn Ala Thr Leu Ser Val His Gln Leu Val Glu Asn
                 185                 190                 195

 Thr Asp Glu Thr Tyr Cys Ile Asp Asn Glu Ala Leu Tyr Asp Ile
                 200                 205                 210

 Cys Phe Arg Thr Leu Lys Leu Thr Thr Pro Thr Tyr Gly Asp Leu
                 215                 220                 225

 Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Cys Leu
                 230                 235                 240

 Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val
                 245                 250                 255

 Asn Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe
                 260                 265                 270

 Ala Pro Leu Thr Ser Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr
                 275                 280                 285

 Val Pro Glu Leu Thr Gln Gln Val Phe Asp Ala Lys Asn Met Met
                 290                 295                 300

 Ala Ala Cys Asp Pro Arg His Gly Arg Tyr Leu Thr Val Ala Ala
                 305                 310                 315

 Val Phe Arg Gly Arg Met Ser Met Lys Glu Val Asp Glu Gln Met
                 320                 325                 330

 Leu Asn Val Gln Asn Lys Asn Ser Ser Tyr Phe Val Glu Trp Ile
                 335                 340                 345

 Pro Asn Asn Val Lys Thr Ala Val Cys Asp Ile Pro Pro Arg Gly
                 350                 355                 360

 Leu Lys Met Ala Val Thr Phe Ile Gly Asn Ser Thr Ala Ile Gln
                 365                 370                 375

 Glu Leu Phe Lys Arg Ile Ser Glu Gln Phe Thr Ala Met Phe Arg
                 380                 385                 390

 Arg Lys Ala Phe Leu His Trp Tyr Thr Gly Glu Gly Met Asp Glu
                 395                 400                 405

 Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn Asp Leu Val Ser
                 410                 415                 420

 Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Glu Glu Glu Glu Asp
                 425                 430                 435

 Phe Gly Glu Glu Ala Glu Glu Glu Ala
                 440

<210> 2427
<211> 3678
<212> DNA
<213> Homo sapien

<400> 2427
 ggcacgaggg ccagtttctg cagtggaggt cgcgactgag ggacgggaca 50

 gagaagtcgc gaaagtgggc cagaggttct gcgacaccac ctcgggtgag 100

 ctgcgccagg cccgggatag ggactgttgt gttcgaatgc ccgccccggt 150

 cggccgccgc tccccgccta gtccacggag ctcaatggcg gcagtcgcgc 200

 tgagggactc ggctcagggt atgacctttg aggatgtggc catttatttc 250

 tcccaagaag agtgggagct ccttgatgag tctcagaggt tcctgtactg 300

 cgatgtgatg ctggagaact ttgcacatgt aacatccctg ggttattgcc 350

 atggaatgga gaatgaggcg atagcttctg agcagagtgt atctatacag 400

 gtcaggactt ctaagggcaa tacacccacc cagaaaactc acctcagtga 450

 gattaagatg tgtgtcccag tcttgaaaga cattttgcct gcggctgagc 500

 accaaaccac atcccctgtg caaaagtcat acttgggtag cacaagcatg 550

 agaggcttct gcttcagtgc tgaccttcac cagcatcaaa agcattacaa 600

 tgaagaagag ccctggaaaa ggaaggtgga tgaggctaca tttgtgaccg 650

 gctgcagatt ccatgtgttg aattatttca cctgtgggga ggccttccca 700

 gcccccacgg acctactcca acacgaagcc actcccagtg gtgaggagcc 750

 acacagtagc agcagcaagc atatacaggc atttttcaat gcaaaaagtt 800

 attacaagtg gggtgaatac agaaaagctt caagccacaa acacacactt 850

 gttcagcatc agagtgtctg ttctgaagga gggctttatg agtgtagcaa 900

 atgtgagaaa gccttcactt gcaagaacac acttgttcag caccagcaaa 950

 ttcacactgg acaaaagatg tttgagtgta gtgaatgtga ggaatccttt 1000

 agcaaaaagt gccacctaat cttacacaag ataattcaca ctggagaaag 1050

 gccttatgaa tgcagtgatc gtgagaaagc ctttatccat aaatctgaat 1100

 tcattcacca ccagagacgt cacactggag gagtgcgtca tgagtgtggt 1150

 gaatgtagga aaacctttag ctacaaatct aacctcattg aacaccagag 1200

 agttcacact ggagaaaggc cttatgaatg tggcgagtgc gggaaatcct 1250

 ttagacaaag ctctagcctt tttcgacacc agagagttca ctctggagaa 1300

 aggccttatc agtgctgtga gtgtgggaaa tcctttagac aaatcttcaa 1350

 tctcattcga catagaagag ttcacactgg agaaatgcct tatcagtgca 1400

 gtgattgtgg gaaatctttt agctgcaaat cggaactcat tcaacaccag 1450

 agaattcaca gtggagaaag accttatgaa tgcagagaat gtgggaaatc 1500

 ctttagacaa ttctctaacc tcattcgaca ccgcagcatt cacactggtg 1550

 ataggcctta tgagtgcagt gaatgtgaga aatcctttag ccgcaaattt 1600

 atcctgattc aacaccaaag agttcacact ggagaaagac cttatgaatg 1650

 cagtgaatgt ggaaaatcct ttacccgcaa atctgacctc attcaacacc 1700

 ggagaattca tactggcaca agaccttatg agtgcagtga atgtggcaaa 1750

 tcttttagac agcgctctgg cctcattcag caccggagac ttcatactgg 1800

 agaaaggcct tatgaatgta gtgaatgtgg aaagtctttt agccaaagtg 1850

 ctagcctcat tcaacaccag agagttcaca ctggagaaag gccttatgaa 1900

 tgtagtgaat gtgggaaatc ctttagccag agctctagcc tcattcaaca 1950

 ccagagaggt cacactggag aaagacctta tgagtgcagt caatgtggga 2000

 aaccctttac ccacaaatca gaccttattc agcaccaaag agttcacact 2050

 ggagaaaggc cttatgaatg cagtgaatgt gggaaatcct ttagccgcaa 2100

 atctaacctc attcgacatc ggagagttca cactgaagaa aggccttaaa 2150

 tgtgaaggga atgtgctatt tctttattca gtataatagc actggaggag 2200

 actgtggtag ccatcttcgt aaatttaaac tttgagcacc cacagtgggg 2250

 tattcttcat aagtttcagg tatgtgggaa gctctgagga ggttcattgt 2300

 aatttctaat ctgccgaggc ctatagcctg atttatgtca ctgccaattt 2350

 ctgaggctga agccatttca catttcaccc ctaccacctg gcaggtgcac 2400

 accatgtgca tgagtcactt ccccacagtg ctcagagaag caaacctctg 2450

 tactctccca tttgcttggg gaaattatta atagcccaag catgtagggt 2500

 cttcatgtct tttctctgac tttagagtat acacctgacc cagttgtggt 2550

 ccagagaatc tgagttgtgc tgtcagcttt ctaaggatta cctttttaag 2600

 gaacattgtc ggtctcacat gatgcttgta atgaattttt ccacattctg 2650

 attcaccagc ctggaaactg cttggtgcac attgctttaa tttataatgt 2700

 ttttataaag gttttaaaaa aatttacgca cctttaatct tgggtgttct 2750

 attcattgca tagaatgact tgtaagcaga atagtgatgt cagcatgaag 2800

 gggtgaatag attttgtgga gatctcaaac tttctgtact cagaagggac 2850

 aatgtgatgg cagaagacag ctctttgttc tgtattgctc taattggcct 2900

 gctgcccaag gcctcaaagt aaagactgcc aggctttgtg ttcctgtatt 2950

 gtggcctggt gccatttttg tcaggtcaga ggtcaccatg aaaaggaggc 3000

 agttgtgaca atccccagtg cttctgtgaa cgtgaatttt gttcagttgt 3050

 ccacaggaga tccacataat tcctagcact ggtgagggga atctgttgcc 3100

 caggtcctgc aaaggagcca tgtgccatgg catataagtc agtgtagact 3150

 ggtgccattt gttgtcagac tataggtgtg gaggtgaaat tacaggttca 3200

 acagtaattg ggacagaaac tccaggtaaa tggggagtgg agaagactgc 3250

 agtaaattag atggaatgac tcttctaaaa gttcatctac aaattttcca 3300

 gtgaatatgg ttgtgtagga tcagtgcata cagaaattct caggatcttc 3350

 tgtttactat cgctgagatc attatcagaa aatagtctgg ccgggcatgg 3400

 tgtaatccta acactttggg aggccaaggc gggcggattg cctgagctca 3450

 ggagttcaag accagcctgg gcaacatggt gaaatcccat gtctactaaa 3500

 atacaaaaaa ttagccaggc gtggcagcat gcgcctatag tcccagccac 3550

 ttgggaggct gaggcaggag aatcgcttga acccagaagg cggaagttgc 3600

 agtgagctga gattgcacca ctgcactcca gcccaggcaa cagagtgaga 3650

 ctccgtctcc aaaaaaaaaa aaaaaaaa 3678

<210> 2428
<211> 654
<212> PRT
<213> Homo sapien

<400> 2428
 Met Ala Ala Val Ala Leu Arg Asp Ser Ala Gln Gly Met Thr Phe
   1               5                  10                  15

 Glu Asp Val Ala Ile Tyr Phe Ser Gln Glu Glu Trp Glu Leu Leu
                  20                  25                  30

 Asp Glu Ser Gln Arg Phe Leu Tyr Cys Asp Val Met Leu Glu Asn
                  35                  40                  45

 Phe Ala His Val Thr Ser Leu Gly Tyr Cys His Gly Met Glu Asn
                  50                  55                  60

 Glu Ala Ile Ala Ser Glu Gln Ser Val Ser Ile Gln Val Arg Thr
                  65                  70                  75

 Ser Lys Gly Asn Thr Pro Thr Gln Lys Thr His Leu Ser Glu Ile
                  80                  85                  90

 Lys Met Cys Val Pro Val Leu Lys Asp Ile Leu Pro Ala Ala Glu
                  95                 100                 105

 His Gln Thr Thr Ser Pro Val Gln Lys Ser Tyr Leu Gly Ser Thr
                 110                 115                 120

 Ser Met Arg Gly Phe Cys Phe Ser Ala Asp Leu His Gln His Gln
                 125                 130                 135

 Lys His Tyr Asn Glu Glu Glu Pro Trp Lys Arg Lys Val Asp Glu
                 140                 145                 150

 Ala Thr Phe Val Thr Gly Cys Arg Phe His Val Leu Asn Tyr Phe
                 155                 160                 165

 Thr Cys Gly Glu Ala Phe Pro Ala Pro Thr Asp Leu Leu Gln His
                 170                 175                 180

 Glu Ala Thr Pro Ser Gly Glu Glu Pro His Ser Ser Ser Ser Lys
                 185                 190                 195

 His Ile Gln Ala Phe Phe Asn Ala Lys Ser Tyr Tyr Lys Trp Gly
                 200                 205                 210

 Glu Tyr Arg Lys Ala Ser Ser His Lys His Thr Leu Val Gln His
                 215                 220                 225

 Gln Ser Val Cys Ser Glu Gly Gly Leu Tyr Glu Cys Ser Lys Cys
                 230                 235                 240

 Glu Lys Ala Phe Thr Cys Lys Asn Thr Leu Val Gln His Gln Gln
                 245                 250                 255

 Ile His Thr Gly Gln Lys Met Phe Glu Cys Ser Glu Cys Glu Glu
                 260                 265                 270

 Ser Phe Ser Lys Lys Cys His Leu Ile Leu His Lys Ile Ile His
                 275                 280                 285

 Thr Gly Glu Arg Pro Tyr Glu Cys Ser Asp Arg Glu Lys Ala Phe
                 290                 295                 300

 Ile His Lys Ser Glu Phe Ile His His Gln Arg Arg His Thr Gly
                 305                 310                 315

 Gly Val Arg His Glu Cys Gly Glu Cys Arg Lys Thr Phe Ser Tyr
                 320                 325                 330

 Lys Ser Asn Leu Ile Glu His Gln Arg Val His Thr Gly Glu Arg
                 335                 340                 345

 Pro Tyr Glu Cys Gly Glu Cys Gly Lys Ser Phe Arg Gln Ser Ser
                 350                 355                 360

 Ser Leu Phe Arg His Gln Arg Val His Ser Gly Glu Arg Pro Tyr
                 365                 370                 375

 Gln Cys Cys Glu Cys Gly Lys Ser Phe Arg Gln Ile Phe Asn Leu
                 380                 385                 390

 Ile Arg His Arg Arg Val His Thr Gly Glu Met Pro Tyr Gln Cys
                 395                 400                 405

 Ser Asp Cys Gly Lys Ser Phe Ser Cys Lys Ser Glu Leu Ile Gln
                 410                 415                 420

 His Gln Arg Ile His Ser Gly Glu Arg Pro Tyr Glu Cys Arg Glu
                 425                 430                 435

 Cys Gly Lys Ser Phe Arg Gln Phe Ser Asn Leu Ile Arg His Arg
                 440                 445                 450

 Ser Ile His Thr Gly Asp Arg Pro Tyr Glu Cys Ser Glu Cys Glu
                 455                 460                 465

 Lys Ser Phe Ser Arg Lys Phe Ile Leu Ile Gln His Gln Arg Val
                 470                 475                 480

 His Thr Gly Glu Arg Pro Tyr Glu Cys Ser Glu Cys Gly Lys Ser
                 485                 490                 495

 Phe Thr Arg Lys Ser Asp Leu Ile Gln His Arg Arg Ile His Thr
                 500                 505                 510

 Gly Thr Arg Pro Tyr Glu Cys Ser Glu Cys Gly Lys Ser Phe Arg
                 515                 520                 525

 Gln Arg Ser Gly Leu Ile Gln His Arg Arg Leu His Thr Gly Glu
                 530                 535                 540

 Arg Pro Tyr Glu Cys Ser Glu Cys Gly Lys Ser Phe Ser Gln Ser
                 545                 550                 555

 Ala Ser Leu Ile Gln His Gln Arg Val His Thr Gly Glu Arg Pro
                 560                 565                 570

 Tyr Glu Cys Ser Glu Cys Gly Lys Ser Phe Ser Gln Ser Ser Ser
                 575                 580                 585

 Leu Ile Gln His Gln Arg Gly His Thr Gly Glu Arg Pro Tyr Glu
                 590                 595                 600

 Cys Ser Gln Cys Gly Lys Pro Phe Thr His Lys Ser Asp Leu Ile
                 605                 610                 615

 Gln His Gln Arg Val His Thr Gly Glu Arg Pro Tyr Glu Cys Ser
                 620                 625                 630

 Glu Cys Gly Lys Ser Phe Ser Arg Lys Ser Asn Leu Ile Arg His
                 635                 640                 645

 Arg Arg Val His Thr Glu Glu Arg Pro
                 650

<210> 2429
<211> 1983
<212> DNA
<213> Homo sapien

<400> 2429
 gaattgaacc acccattttc ctttcttagc caaatcacca aaatgtccag 50

 ttagaacaag aatttagcat tctgcaaaag aagttaacag ctgagataac 100

 gaggaaatat tctgaaatgg atcccaaata tttcatctta attttgtttt 150

 gtggacacct gaacaataca tttttttcaa agacagagac aattacaaca 200

 gagaagcagt cacagcctac cttattcaca tcatcaatgt cacaggtatt 250

 ggctaattct caaaacacaa cagggaatcc tttgggtcaa ccaacacaat 300

 tcagcgacac tttttctgga caatcaatat cacctgccaa agtcactgct 350

 ggacaaccaa caccagctgt ctatacctct tctgaaaaac cagaagcaca 400

 tacttctgct ggacaaccac ttgcctacaa caccaaacaa ccaacaccaa 450

 tagccaacac ctcctcccag caagccgtgt tcacctctgc cagacaacta 500

 ccatctgccc gtacttctac cacacaacca ccaaagtcat ttgtctatac 550

 ttttactcaa caatcatcat ctgtccagat cccttctaga aaacaaataa 600

 ctgttcataa tccatccaca caaccaacat caactgtcaa aaattcacct 650

 aggagtacac caggatttat cttagatact accagtaaca aacaaacccc 700

 acaaaaaaac aattataatt caatagctgc catactaatt ggtgtacttc 750

 tgacttctat gttggtagct ataatcatca ttgtactttg gaaatgctta 800

 aggaaaccag ttttaaatga tcaaaattgg gcaggtagat ctccatttgc 850

 tgatggagaa acccctgaca tttgtatgga taacatcaga gaaaatgaaa 900

 tatccacaaa acgtacatca atcatttcac ttacaccctg gaaaccaagc 950

 aaaagcacac ttttagcaga tgacttagaa attaagttgt ttgaatcaag 1000

 tgaaaacatt gaagactcca acaaccccaa aacagagaaa ataaaagatc 1050

 aagtaaatgg tacatcagaa gatagtgctg atggttcaac agttggaact 1100

 gctgtttctt cttcagatga tgcaggtctg cctccaccac ctccccttct 1150

 ggatttggaa ggacaggaaa gtaaccaatc tgacaaaccc acaatgacaa 1200

 ttgtatctcc tcttccaaat gattctacta gtctccctcc atctctggac 1250

 tgtctcaatc aagactgtgg agatcataaa tctgagataa tacaatcatt 1300

 tccaccgctt gactcactta acttgcccct gccaccagta gattttatga 1350

 aaaaccaaga agattccaac cttgagatcc agtgtcagga gttctctatt 1400

 cctcccaact ctgatcaaga tcttaatgaa tccctgccac ctccacctgc 1450

 agaactgtta taaatattac aacttgcttt ttagctgatc ttccatcctc 1500

 aaatgactct tttttcttta tatgttaaca tatataaaat ggcaactgat 1550

 agtcaatttt gatttttatt caggaactat ctgaaatctg ctcagagcct 1600

 atgtgcatag atgaaacttt tttttaaaaa aagttattta acagtaatct 1650

 atttactaat tatagtacct atctttaaag tatagtacat tttacatatg 1700

 taaatggtat gtttcaataa tttaagaact ctgaaacaat ctacatatac 1750

 ttattaccca gtacagtttt ttttcccctg aaaagctgtg tataaaatta 1800

 tggtgaataa acttttatgt ttccatttca aagaccaggg tggagaggaa 1850

 taagagacta agtatatgct tcaagtttta aattaatacc tcaagtatta 1900

 aataaatatt ccaagtttgt gggaatggga gattaaaatg catgtttgag 1950

 agtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1983

<210> 2430
<211> 448
<212> PRT
<213> Homo sapien

<400> 2430
 Met Asp Pro Lys Tyr Phe Ile Leu Ile Leu Phe Cys Gly His Leu
   1               5                  10                  15

 Asn Asn Thr Phe Phe Ser Lys Thr Glu Thr Ile Thr Thr Glu Lys
                  20                  25                  30

 Gln Ser Gln Pro Thr Leu Phe Thr Ser Ser Met Ser Gln Val Leu
                  35                  40                  45

 Ala Asn Ser Gln Asn Thr Thr Gly Asn Pro Leu Gly Gln Pro Thr
                  50                  55                  60

 Gln Phe Ser Asp Thr Phe Ser Gly Gln Ser Ile Ser Pro Ala Lys
                  65                  70                  75

 Val Thr Ala Gly Gln Pro Thr Pro Ala Val Tyr Thr Ser Ser Glu
                  80                  85                  90

 Lys Pro Glu Ala His Thr Ser Ala Gly Gln Pro Leu Ala Tyr Asn
                  95                 100                 105

 Thr Lys Gln Pro Thr Pro Ile Ala Asn Thr Ser Ser Gln Gln Ala
                 110                 115                 120

 Val Phe Thr Ser Ala Arg Gln Leu Pro Ser Ala Arg Thr Ser Thr
                 125                 130                 135

 Thr Gln Pro Pro Lys Ser Phe Val Tyr Thr Phe Thr Gln Gln Ser
                 140                 145                 150

 Ser Ser Val Gln Ile Pro Ser Arg Lys Gln Ile Thr Val His Asn
                 155                 160                 165

 Pro Ser Thr Gln Pro Thr Ser Thr Val Lys Asn Ser Pro Arg Ser
                 170                 175                 180

 Thr Pro Gly Phe Ile Leu Asp Thr Thr Ser Asn Lys Gln Thr Pro
                 185                 190                 195

 Gln Lys Asn Asn Tyr Asn Ser Ile Ala Ala Ile Leu Ile Gly Val
                 200                 205                 210

 Leu Leu Thr Ser Met Leu Val Ala Ile Ile Ile Ile Val Leu Trp
                 215                 220                 225

 Lys Cys Leu Arg Lys Pro Val Leu Asn Asp Gln Asn Trp Ala Gly
                 230                 235                 240

 Arg Ser Pro Phe Ala Asp Gly Glu Thr Pro Asp Ile Cys Met Asp
                 245                 250                 255

 Asn Ile Arg Glu Asn Glu Ile Ser Thr Lys Arg Thr Ser Ile Ile
                 260                 265                 270

 Ser Leu Thr Pro Trp Lys Pro Ser Lys Ser Thr Leu Leu Ala Asp
                 275                 280                 285

 Asp Leu Glu Ile Lys Leu Phe Glu Ser Ser Glu Asn Ile Glu Asp
                 290                 295                 300

 Ser Asn Asn Pro Lys Thr Glu Lys Ile Lys Asp Gln Val Asn Gly
                 305                 310                 315

 Thr Ser Glu Asp Ser Ala Asp Gly Ser Thr Val Gly Thr Ala Val
                 320                 325                 330

 Ser Ser Ser Asp Asp Ala Gly Leu Pro Pro Pro Pro Pro Leu Leu
                 335                 340                 345

 Asp Leu Glu Gly Gln Glu Ser Asn Gln Ser Asp Lys Pro Thr Met
                 350                 355                 360

 Thr Ile Val Ser Pro Leu Pro Asn Asp Ser Thr Ser Leu Pro Pro
                 365                 370                 375

 Ser Leu Asp Cys Leu Asn Gln Asp Cys Gly Asp His Lys Ser Glu
                 380                 385                 390

 Ile Ile Gln Ser Phe Pro Pro Leu Asp Ser Leu Asn Leu Pro Leu
                 395                 400                 405

 Pro Pro Val Asp Phe Met Lys Asn Gln Glu Asp Ser Asn Leu Glu
                 410                 415                 420

 Ile Gln Cys Gln Glu Phe Ser Ile Pro Pro Asn Ser Asp Gln Asp
                 425                 430                 435

 Leu Asn Glu Ser Leu Pro Pro Pro Pro Ala Glu Leu Leu
                 440                 445

<210> 2431
<211> 1480
<212> DNA
<213> Homo sapien

<400> 2431
 cgcgagccgg gaccacgccg acccagcgtg cccaggccga ggaaagcgcg 50

 gcggcggcag tccgaagacc caccggactg aaagagaagg acgaggtcat 100

 cttcggacgg gaggggcaag ccagccatcc tgggacccca ggcgtgcagg 150

 ttctctttga gggtattcca ccctgcaaaa agcatgtatt catggtcagc 200

 tctcagcaag gccagtagca gagtggtaaa ggccttggcc ctccaaggct 250

 gggaaaagac aatgacaagt caaatccaga cctatgttgg atgttggtct 300

 actaggtgac tgtctcctgg aaatgttatg cagctcagca aggtgaagtt 350

 tcgaaatcag tatgacaatg atgtcactgt ttggagcccc cagggcagga 400

 ttcatcaaat tgaatatgca atggaagctg ttaaacaagg ttcagccaca 450

 gttggtctga aatcaaaaac tcatgcagtt ttggttgcat tgaaaagggc 500

 gcaatcagag cttgcagctc atcagaaaaa aattctccat gttgacaacc 550

 atattggtat ctcaattgcg gggcttactg ctgatgctag actgttatgt 600

 aattttatgc gtcaggagtg tttggattcc agatttgtat tcgatagacc 650

 actgcctgtg tctcgtcttg tatctctaat tggaagcaag acccagatac 700

 caacacaacg atatggccgg agaccatatg gtgttggtct ccttattgct 750

 ggttatgatg atatgggccc tcacattttc caaacctgtc catctgctaa 800

 ctattttgac tgcagagcca tgtccattgg agcccgttcc caatcagctc 850

 gtacttactt ggagagacat atgtctgaat ttatggagtg taatttaaat 900

 gaactagtta aacatggtct gcgtgcctta agagagacgc ttcctgcaga 950

 acaggacctg actacaaaga atgtttccat tggaattgtt ggtaaagact 1000

 tggagtttac aatctatgat gatgatgatg tgtctccatt cctggaaggt 1050

 cttgaagaaa gaccacagag aaaggcacag cctgctcaac ctgctgatga 1100

 acctgcagaa aaggctgatg aaccaatgga acattaagtg ataagccagt 1150

 ctatatatgt attatcaaat atgtaagaat acaggcacca catactgatg 1200

 acaataatct atactttgaa ccaaaagttg cagagtggtg gaatgctatg 1250

 ttttaggaat cagtccagat gtgagttttt tccaagcaac ctcactgaaa 1300

 cctatataat ggaatacatt tttctttgaa agggtctgta taatcatttt 1350

 ctagaaagta tgggtatcta tactaatgtt tttatatgaa gaacataggt 1400

 gtctttgtgg ttttaaagac aactgtgaaa taaaattgtt tcaccgcctg 1450

 gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1480

<210> 2432
<211> 269
<212> PRT
<213> Homo sapien

<400> 2432
 Met Gln Leu Ser Lys Val Lys Phe Arg Asn Gln Tyr Asp Asn Asp
   1               5                  10                  15

 Val Thr Val Trp Ser Pro Gln Gly Arg Ile His Gln Ile Glu Tyr
                  20                  25                  30

 Ala Met Glu Ala Val Lys Gln Gly Ser Ala Thr Val Gly Leu Lys
                  35                  40                  45

 Ser Lys Thr His Ala Val Leu Val Ala Leu Lys Arg Ala Gln Ser
                  50                  55                  60

 Glu Leu Ala Ala His Gln Lys Lys Ile Leu His Val Asp Asn His
                  65                  70                  75

 Ile Gly Ile Ser Ile Ala Gly Leu Thr Ala Asp Ala Arg Leu Leu
                  80                  85                  90

 Cys Asn Phe Met Arg Gln Glu Cys Leu Asp Ser Arg Phe Val Phe
                  95                 100                 105

 Asp Arg Pro Leu Pro Val Ser Arg Leu Val Ser Leu Ile Gly Ser
                 110                 115                 120

 Lys Thr Gln Ile Pro Thr Gln Arg Tyr Gly Arg Arg Pro Tyr Gly
                 125                 130                 135

 Val Gly Leu Leu Ile Ala Gly Tyr Asp Asp Met Gly Pro His Ile
                 140                 145                 150

 Phe Gln Thr Cys Pro Ser Ala Asn Tyr Phe Asp Cys Arg Ala Met
                 155                 160                 165

 Ser Ile Gly Ala Arg Ser Gln Ser Ala Arg Thr Tyr Leu Glu Arg
                 170                 175                 180

 His Met Ser Glu Phe Met Glu Cys Asn Leu Asn Glu Leu Val Lys
                 185                 190                 195

 His Gly Leu Arg Ala Leu Arg Glu Thr Leu Pro Ala Glu Gln Asp
                 200                 205                 210

 Leu Thr Thr Lys Asn Val Ser Ile Gly Ile Val Gly Lys Asp Leu
                 215                 220                 225

 Glu Phe Thr Ile Tyr Asp Asp Asp Asp Val Ser Pro Phe Leu Glu
                 230                 235                 240

 Gly Leu Glu Glu Arg Pro Gln Arg Lys Ala Gln Pro Ala Gln Pro
                 245                 250                 255

 Ala Asp Glu Pro Ala Glu Lys Ala Asp Glu Pro Met Glu His
                 260                 265

<210> 2433
<211> 749
<212> DNA
<213> Homo sapien

<400> 2433
 atggcggcta acgctactac caacccgtcg cagctgctgc cgttagagct 50

 tgtggacaaa tgtataggat caagaattca catcgtgatg aagagtgata 100

 aggaaattgt tggtactctt ctaggatttg atgactttgt caatatggta 150

 ctggaagatg tcactgagtt tgaaatcaca ccagaaggaa gaaggattac 200

 taaattagat cagattttgc taaatggaaa taatataaca atgctggttc 250

 ctggaggaga aggacctgaa gtgtgaatga gtttccttga cttacactag 300

 attttgtttt ggcttataat gacaagaaaa tggaattttt tttcccactt 350

 tctaatgttt aaatcccata aagctaagtt tcccgttaaa gggaagtgct 400

 ttgaagatgt gtacccattt ttgtaagtta atcatgatta tcctggaaaa 450

 agaagaaaag aacttcttct tttgcagatg aaaataaagg tgtttttggt 500

 taactgtcat tttgtttatt ctactgcagt agccagtgga acaaagtttg 550

 tagttatttt gccacttact tttctgtcat tatatgctta tttgttttgt 600

 catttacgtg accatttgat tctcaaacaa aagttgttcc aaacaaaatg 650

 atgaactttg atttgaacag gtgcatttaa acaaccggaa atgatcactt 700

 agaaaattca attaaaatgc tgttgttttg taaaaaaaaa aaaaaaaaa 749

<210> 2434
<211> 91
<212> PRT
<213> Homo sapien

<400> 2434
 Met Ala Ala Asn Ala Thr Thr Asn Pro Ser Gln Leu Leu Pro Leu
   1               5                  10                  15

 Glu Leu Val Asp Lys Cys Ile Gly Ser Arg Ile His Ile Val Met
                  20                  25                  30

 Lys Ser Asp Lys Glu Ile Val Gly Thr Leu Leu Gly Phe Asp Asp
                  35                  40                  45

 Phe Val Asn Met Val Leu Glu Asp Val Thr Glu Phe Glu Ile Thr
                  50                  55                  60

 Pro Glu Gly Arg Arg Ile Thr Lys Leu Asp Gln Ile Leu Leu Asn
                  65                  70                  75

 Gly Asn Asn Ile Thr Met Leu Val Pro Gly Gly Glu Gly Pro Glu
                  80                  85                  90

 Val


<210> 2435
<211> 1542
<212> DNA
<213> Homo sapien

<400> 2435
 gagatccttg ttgccgtccc ttcgcctcct tcaccgccgc agaccccttc 50

 aagttctagt catgcgtgag tgcatctcca tccacgttgg ccaggctggt 100

 gtccagattg gcaatgcctg ctgggagctc tactgcctgg aacacggcat 150

 ccagcccgat ggccagatgc caagtgacaa gaccattggg ggaggagatg 200

 attccttcaa caccttcttc agtgaaacgg gtgctggcaa gcatgtgccc 250

 cgggcagtgt ttgtagactt ggaacccaca gtcattgatg aagttcgcac 300

 tggcacttac cgccagctct tccaccctga gcaactcatc acaggcaagg 350

 aagatgctgc caataactat gcccgagggc actacaccat tggcaaggag 400

 atcattgacc tcgtgttgga ccgaattcgc aagctggctg accagtgcac 450

 cggtcttcag ggcttcttgg ttttccacag ctttggtggg ggaactggtt 500

 ctgggttcac ctcgctgctc atggaacgtc tctcagttga ttatggcaag 550

 aagtccaagc tggagttctc catttacccg gcgccccagg tttccacagc 600

 tgtagttgag ccctacaact ccatcctcac cacccacacc accctggagc 650

 actctgattg tgccttcatg gtagacaatg aggccatcta tgacatctgt 700

 cgtagaaacc tcgatatcga gcgcccaacc tacactaacc ttaaccgcct 750

 tattagccag attgtgtcct ccatcactgc ttccctgaga tttgatggag 800

 ccctgaatgt tgacctgaca gaattccaga ccaacctggt gccctacccc 850

 cgcatccact tccctctggc cacatatgcc cctgtcatct ctgctgagaa 900

 agcctaccac gaacagctta ctgtagcaga gatcaccaat gcttgctttg 950

 agccagccaa ccagatggtg aaatgtgacc ctcgccatgg taaatacatg 1000

 gcttgctgcc tgttataccg tggtgacgtg gttcccaaag atgtcaatgc 1050

 tgccattgcc accatcaaaa ccaagcgtac catccagttt gtggattggt 1100

 gccccactgg cttcaaggtt ggcattaatt accagcctcc cactgtggtg 1150

 cctggcggag acctggccaa ggtacagaga gctgtgtgca tgctgagcaa 1200

 taccacagct gttgccgagg cctgggctcg cctggaccac aagtttgacc 1250

 tgatgtatgc caagcgtgcc tttgttcact ggtacgtggg tgaggggatg 1300

 gaggaaggcg agttttcaga ggcccgtgag gacatggctg cccttgagaa 1350

 ggattatgag gaggttggag cagatagtgc tgacggagag gatgagggtg 1400

 aagagtatta acctgtgtgc tgtactttta cactcctttg tcttggaact 1450

 gtcttatttt tgttctgtaa atgtctattg ccgtaaattg ttaataaaat 1500

 tgatgtttcc attttaaaaa aaaaaaaaaa aaaaaaaaaa aa 1542

<210> 2436
<211> 449
<212> PRT
<213> Homo sapien

<400> 2436
 Met Arg Glu Cys Ile Ser Ile His Val Gly Gln Ala Gly Val Gln
   1               5                  10                  15

 Ile Gly Asn Ala Cys Trp Glu Leu Tyr Cys Leu Glu His Gly Ile
                  20                  25                  30

 Gln Pro Asp Gly Gln Met Pro Ser Asp Lys Thr Ile Gly Gly Gly
                  35                  40                  45

 Asp Asp Ser Phe Asn Thr Phe Phe Ser Glu Thr Gly Ala Gly Lys
                  50                  55                  60

 His Val Pro Arg Ala Val Phe Val Asp Leu Glu Pro Thr Val Ile
                  65                  70                  75

 Asp Glu Val Arg Thr Gly Thr Tyr Arg Gln Leu Phe His Pro Glu
                  80                  85                  90

 Gln Leu Ile Thr Gly Lys Glu Asp Ala Ala Asn Asn Tyr Ala Arg
                  95                 100                 105

 Gly His Tyr Thr Ile Gly Lys Glu Ile Ile Asp Leu Val Leu Asp
                 110                 115                 120

 Arg Ile Arg Lys Leu Ala Asp Gln Cys Thr Gly Leu Gln Gly Phe
                 125                 130                 135

 Leu Val Phe His Ser Phe Gly Gly Gly Thr Gly Ser Gly Phe Thr
                 140                 145                 150

 Ser Leu Leu Met Glu Arg Leu Ser Val Asp Tyr Gly Lys Lys Ser
                 155                 160                 165

 Lys Leu Glu Phe Ser Ile Tyr Pro Ala Pro Gln Val Ser Thr Ala
                 170                 175                 180

 Val Val Glu Pro Tyr Asn Ser Ile Leu Thr Thr His Thr Thr Leu
                 185                 190                 195

 Glu His Ser Asp Cys Ala Phe Met Val Asp Asn Glu Ala Ile Tyr
                 200                 205                 210

 Asp Ile Cys Arg Arg Asn Leu Asp Ile Glu Arg Pro Thr Tyr Thr
                 215                 220                 225

 Asn Leu Asn Arg Leu Ile Ser Gln Ile Val Ser Ser Ile Thr Ala
                 230                 235                 240

 Ser Leu Arg Phe Asp Gly Ala Leu Asn Val Asp Leu Thr Glu Phe
                 245                 250                 255

 Gln Thr Asn Leu Val Pro Tyr Pro Arg Ile His Phe Pro Leu Ala
                 260                 265                 270

 Thr Tyr Ala Pro Val Ile Ser Ala Glu Lys Ala Tyr His Glu Gln
                 275                 280                 285

 Leu Thr Val Ala Glu Ile Thr Asn Ala Cys Phe Glu Pro Ala Asn
                 290                 295                 300

 Gln Met Val Lys Cys Asp Pro Arg His Gly Lys Tyr Met Ala Cys
                 305                 310                 315

 Cys Leu Leu Tyr Arg Gly Asp Val Val Pro Lys Asp Val Asn Ala
                 320                 325                 330

 Ala Ile Ala Thr Ile Lys Thr Lys Arg Thr Ile Gln Phe Val Asp
                 335                 340                 345

 Trp Cys Pro Thr Gly Phe Lys Val Gly Ile Asn Tyr Gln Pro Pro
                 350                 355                 360

 Thr Val Val Pro Gly Gly Asp Leu Ala Lys Val Gln Arg Ala Val
                 365                 370                 375

 Cys Met Leu Ser Asn Thr Thr Ala Val Ala Glu Ala Trp Ala Arg
                 380                 385                 390

 Leu Asp His Lys Phe Asp Leu Met Tyr Ala Lys Arg Ala Phe Val
                 395                 400                 405

 His Trp Tyr Val Gly Glu Gly Met Glu Glu Gly Glu Phe Ser Glu
                 410                 415                 420

 Ala Arg Glu Asp Met Ala Ala Leu Glu Lys Asp Tyr Glu Glu Val
                 425                 430                 435

 Gly Ala Asp Ser Ala Asp Gly Glu Asp Glu Gly Glu Glu Tyr
                 440                 445

<210> 2437
<211> 1494
<212> DNA
<213> Homo sapien

<400> 2437
 ttgcagccgc cggcagctac tgcaaggcaa aagccggagt ggacgtgtct 50

 tttgaaactg ctgctctttc acttctcagg cgtcaccgag agctcagcac 100

 ccaggctgaa ctctgtacca tttggaagaa tggaagctga tgcatctgtt 150

 gacatgtttt ccaaagtcct ggagcatcag ctgcttcaga ctaccaaact 200

 ggtggaagaa catttggatt ctgaaattca aaaactggat cagatggatg 250

 aggatgaatt ggaacgcctt aaagaaaaga gactccaggc actaaggaaa 300

 gctcaacagc agaaacaaga atggctttct aaaggacatg gggaatacag 350

 agaaatccct agtgaaagag acttttttca agaagtcaag gagagtgaaa 400

 atgtggtttg ccatttctac agagactcca cattcaggtg taaaatacta 450

 gacagacatc tggcaatatt gtccaagaaa cacctcgaga ccaaattttt 500

 gaagctgaat gtggaaaaag cacctttcct ttgtgagaga ctgcatatca 550

 aagtcattcc cacactagca ctgctaaaag atgggaaaac acaagattat 600

 gttgttgggt ttactgacct aggaaataca gatgacttca ccacagaaac 650

 tttagaatgg aggctcggtt cttctgacat tcttaattac agtggaaatt 700

 taatggagcc accatttcag aaccaaaaga aatttggaac aaacttcaca 750

 aagctggaaa agaaaactat ccgaggaaag aaatatgatt cagactctga 800

 tgatgattag agctcaataa ttctttgtaa attgtctttt tttttctgct 850

 tcagatttaa atgtgttttt aaaattctat taatgtctat acattggtca 900

 cctaaatact catattctcg agttttatac agttgtatca catcgaaaag 950

 tgtctttact gttttctgtg tggccatcat gtttaagttg aggaaaactc 1000

 agttcttaaa ttatctggga agggtctgga ttctctattt ttgagattga 1050

 ctttatcaca atatgattct tacatcttta taccatttac aattgtgttt 1100

 tagatctaca gagttagaaa ttcgaaaact attccaggac taattcttaa 1150

 tcggcattat ttatacaaga ggtcaagtaa catttactag cgcaatactg 1200

 cacttgtaaa tgaattataa acgctcttct ggaatatatt taaataacca 1250

 ttaaagaact gcttattcat tctggacact gcatgttgat gttgaatcaa 1300

 ctgatgccag cagaaagcta ttttgatttg tgaacatact gccttattta 1350

 aagggtcctg attgcttgta ttttaagaca ttcattaaaa agaaaccagg 1400

 aaacactttt gaaataacag cataaggaac ttcactgtct ctgctcaata 1450

 aaatacctgt aactggaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1494

<210> 2438
<211> 226
<212> PRT
<213> Homo sapien

<400> 2438
 Met Glu Ala Asp Ala Ser Val Asp Met Phe Ser Lys Val Leu Glu
   1               5                  10                  15

 His Gln Leu Leu Gln Thr Thr Lys Leu Val Glu Glu His Leu Asp
                  20                  25                  30

 Ser Glu Ile Gln Lys Leu Asp Gln Met Asp Glu Asp Glu Leu Glu
                  35                  40                  45

 Arg Leu Lys Glu Lys Arg Leu Gln Ala Leu Arg Lys Ala Gln Gln
                  50                  55                  60

 Gln Lys Gln Glu Trp Leu Ser Lys Gly His Gly Glu Tyr Arg Glu
                  65                  70                  75

 Ile Pro Ser Glu Arg Asp Phe Phe Gln Glu Val Lys Glu Ser Glu
                  80                  85                  90

 Asn Val Val Cys His Phe Tyr Arg Asp Ser Thr Phe Arg Cys Lys
                  95                 100                 105

 Ile Leu Asp Arg His Leu Ala Ile Leu Ser Lys Lys His Leu Glu
                 110                 115                 120

 Thr Lys Phe Leu Lys Leu Asn Val Glu Lys Ala Pro Phe Leu Cys
                 125                 130                 135

 Glu Arg Leu His Ile Lys Val Ile Pro Thr Leu Ala Leu Leu Lys
                 140                 145                 150

 Asp Gly Lys Thr Gln Asp Tyr Val Val Gly Phe Thr Asp Leu Gly
                 155                 160                 165

 Asn Thr Asp Asp Phe Thr Thr Glu Thr Leu Glu Trp Arg Leu Gly
                 170                 175                 180

 Ser Ser Asp Ile Leu Asn Tyr Ser Gly Asn Leu Met Glu Pro Pro
                 185                 190                 195

 Phe Gln Asn Gln Lys Lys Phe Gly Thr Asn Phe Thr Lys Leu Glu
                 200                 205                 210

 Lys Lys Thr Ile Arg Gly Lys Lys Tyr Asp Ser Asp Ser Asp Asp
                 215                 220                 225

 Asp


<210> 2439
<211> 1157
<212> DNA
<213> Homo sapien

<400> 2439
 accgccagcc cgggagagct gccgggagtt ccccgggagc gctgccggga 50

 gttccccggg agcctcaggt ggtgactatc ctgttgagaa gcaaaagata 100

 ctttgcaagt aaaaaatatg cctcccaagt ttaagcgcca cctcaatgat 150

 gatgatgtca caggttctgt gaaaagtgaa aggagaaatc ttttggaaga 200

 tgattcagat gaagaagagg acttttttct aaggggacca tctggaccaa 250

 gatttggacc tagaaatgat aaaattaagc atgttcagaa tcaagtggat 300

 gaagttattg atgtcatgca agaaaatatt acaaaggtaa ttgagagagg 350

 ggagagacta gatgaactac aggacaaatc agaaagctta tcggataatg 400

 caacagcttt tagcaacaga tccaaacaac ttcgaaggca aatgtggtgg 450

 cgtggatgca aaataaaagc catcatggct ttggttgctg ctatcctttt 500

 gctagtgatt atcattctta tagtcatgaa ataccgtact tgatttgatg 550

 acagagatct tcattaaaca agatctggga cagtaataaa agattgctgc 600

 ataatttaaa tgaaacctat gtgtatataa ctttcaaaac ttctttttca 650

 agaaactaag aggcaagtat cacttcaaat tggaacgttg agaatgtcca 700

 attatcttct ccctttctaa caaaatgttc ttttaataat tatgtttaag 750

 gcaaagagaa ctagcctcta tttttccata tttcaaggat ctaatttgaa 800

 actagatact tgccagttca ttatttgtgt atataaacac tgattataat 850

 atttcatatt aatattttaa tggcataagg acttgcatta ttgcattagg 900

 gagcgggtca tgctggtggt caggaagcct gtgtagagta ccaaattata 950

 tgttgaaaga gatgcataac cattctgtca atatttgcag aaatatagtt 1000

 cctttcatat tacagttgtt ttgcaagcaa tttccacatt tataggtgta 1050

 acaaaagcta aatgttgtaa atgttgttgc cctcaggtat aactaaaaac 1100

 attccagtaa atatattttt gactgtgtaa aaaaaaaaaa aaaaaaaaaa 1150

 aaaaaaa 1157

<210> 2440
<211> 141
<212> PRT
<213> Homo sapien

<400> 2440
 Met Pro Pro Lys Phe Lys Arg His Leu Asn Asp Asp Asp Val Thr
   1               5                  10                  15

 Gly Ser Val Lys Ser Glu Arg Arg Asn Leu Leu Glu Asp Asp Ser
                  20                  25                  30

 Asp Glu Glu Glu Asp Phe Phe Leu Arg Gly Pro Ser Gly Pro Arg
                  35                  40                  45

 Phe Gly Pro Arg Asn Asp Lys Ile Lys His Val Gln Asn Gln Val
                  50                  55                  60

 Asp Glu Val Ile Asp Val Met Gln Glu Asn Ile Thr Lys Val Ile
                  65                  70                  75

 Glu Arg Gly Glu Arg Leu Asp Glu Leu Gln Asp Lys Ser Glu Ser
                  80                  85                  90

 Leu Ser Asp Asn Ala Thr Ala Phe Ser Asn Arg Ser Lys Gln Leu
                  95                 100                 105

 Arg Arg Gln Met Trp Trp Arg Gly Cys Lys Ile Lys Ala Ile Met
                 110                 115                 120

 Ala Leu Val Ala Ala Ile Leu Leu Leu Val Ile Ile Ile Leu Ile
                 125                 130                 135

 Val Met Lys Tyr Arg Thr
                 140

<210> 2441
<211> 1976
<212> DNA
<213> Homo sapien

<400> 2441
 gccacacggt ctttgagctg agtcgaggtg gaccctttga acgcagtcgc 50

 cctacagccg ctgattcccc ccgcatcgcc tcccgtggaa gcccaggccc 100

 gcttcgcagc tttctccctt tgtctcataa ccatgtccac caacgagaat 150

 gctaatacac cagctgcccg tcttcacaga ttcaagaaca agggaaaaga 200

 cagtacagaa atgaggcgtc gcagaataga ggtcaatgtg gagctgagga 250

 aagctaagaa ggatgaccag atgctgaaga ggagaaatgt aagctcattt 300

 cctgatgatg ctacttctcc gctgcaggaa aaccgcaaca accagggcac 350

 tgtaaattgg tctgttgatg acattgtcaa aggcataaat agcagcaatg 400

 tggaaaatca gctccaagct actcaagctg ccaggaaact actttccaga 450

 gaaaaacagc cccccataga caacataatc cgggctggtt tgattccgaa 500

 atttgtgtcc ttcttgggca gaactgattg tagtcccatt cagtttgaat 550

 ctgcttgggc actcactaac attgcttctg ggacatcaga acaaaccaag 600

 gctgtggtag atggaggtgc catcccagca ttcatttctc tgttggcatc 650

 tccccatgct cacatcagtg aacaagctgt ctgggctcta ggaaacattg 700

 caggtgatgg ctcagtgttc cgagacttgg ttattaagta cggtgcagtt 750

 gacccactgt tggctctcct tgcagttcct gatatgtcat ctttagcatg 800

 tggctactta cgtaatctta cctggacact ttctaatctt tgccgcaaca 850

 agaatcctgc acccccgata gatgctgttg agcagattct tcctacctta 900

 gttcggctcc tgcatcatga tgatccagaa gtgttagcag atacctgctg 950

 ggctatttcc taccttactg atggtccaaa tgaacgaatt ggcatggtgg 1000

 tgaaaacagg agttgtgccc caacttgtga agcttctagg agcttctgaa 1050

 ttgccaattg tgactcctgc cctaagagcc atagggaata ttgtcactgg 1100

 tacagatgaa cagactcagg ttgtgattga tgcaggagca ctcgccgtct 1150

 ttcccagcct gctcaccaac cccaaaacta acattcagaa ggaagctacg 1200

 tggacaatgt caaacatcac agccggccgc caggaccaga tacagcaagt 1250

 tgtgaatcat ggattagtcc cattccttgt cagtgttctc tctaaggcag 1300

 attttaagac acaaaaggaa gctgtgtggg ccgtgaccaa ctataccagt 1350

 ggtggaacag ttgaacagat tgtgtacctt gttcactgtg gcataataga 1400

 accgttgatg aacctcttaa ctgcaaaaga taccaagatt attctggtta 1450

 tcctggatgc catttcaaat atctttcagg ctgctgagaa actaggtgaa 1500

 actgagaaac ttagtataat gattgaagaa tgtggaggct tagacaaaat 1550

 tgaagctcta caaaaccatg aaaatgagtc tgtgtataag gcttcgttaa 1600

 gcttaattga gaagtatttc tctgtagagg aagaggaaga tcaaaacgtt 1650

 gtaccagaaa ctacctctga aggctacact ttccaagttc aggatggggc 1700

 tcctgggacc tttaactttt agatcatgta gctgagacat aaatttgttg 1750

 tgtactacgt ttggtatttt gtcttattgt ttctctacta agaactcttt 1800

 cttaaatgtg gtttgttact gtagcacttt ttacactgaa actatacttg 1850

 aacagttcca actgtacata catactgtat gaagcttgtc ctctgactag 1900

 gtttctaatt tctatgtgga atttcctatc ttgcagcatc ctgtaaataa 1950

 acattcaagt ccacccttaa aaaaaa 1976

<210> 2442
<211> 529
<212> PRT
<213> Homo sapien

<400> 2442
 Met Ser Thr Asn Glu Asn Ala Asn Thr Pro Ala Ala Arg Leu His
   1               5                  10                  15

 Arg Phe Lys Asn Lys Gly Lys Asp Ser Thr Glu Met Arg Arg Arg
                  20                  25                  30

 Arg Ile Glu Val Asn Val Glu Leu Arg Lys Ala Lys Lys Asp Asp
                  35                  40                  45

 Gln Met Leu Lys Arg Arg Asn Val Ser Ser Phe Pro Asp Asp Ala
                  50                  55                  60

 Thr Ser Pro Leu Gln Glu Asn Arg Asn Asn Gln Gly Thr Val Asn
                  65                  70                  75

 Trp Ser Val Asp Asp Ile Val Lys Gly Ile Asn Ser Ser Asn Val
                  80                  85                  90

 Glu Asn Gln Leu Gln Ala Thr Gln Ala Ala Arg Lys Leu Leu Ser
                  95                 100                 105

 Arg Glu Lys Gln Pro Pro Ile Asp Asn Ile Ile Arg Ala Gly Leu
                 110                 115                 120

 Ile Pro Lys Phe Val Ser Phe Leu Gly Arg Thr Asp Cys Ser Pro
                 125                 130                 135

 Ile Gln Phe Glu Ser Ala Trp Ala Leu Thr Asn Ile Ala Ser Gly
                 140                 145                 150

 Thr Ser Glu Gln Thr Lys Ala Val Val Asp Gly Gly Ala Ile Pro
                 155                 160                 165

 Ala Phe Ile Ser Leu Leu Ala Ser Pro His Ala His Ile Ser Glu
                 170                 175                 180

 Gln Ala Val Trp Ala Leu Gly Asn Ile Ala Gly Asp Gly Ser Val
                 185                 190                 195

 Phe Arg Asp Leu Val Ile Lys Tyr Gly Ala Val Asp Pro Leu Leu
                 200                 205                 210

 Ala Leu Leu Ala Val Pro Asp Met Ser Ser Leu Ala Cys Gly Tyr
                 215                 220                 225

 Leu Arg Asn Leu Thr Trp Thr Leu Ser Asn Leu Cys Arg Asn Lys
                 230                 235                 240

 Asn Pro Ala Pro Pro Ile Asp Ala Val Glu Gln Ile Leu Pro Thr
                 245                 250                 255

 Leu Val Arg Leu Leu His His Asp Asp Pro Glu Val Leu Ala Asp
                 260                 265                 270

 Thr Cys Trp Ala Ile Ser Tyr Leu Thr Asp Gly Pro Asn Glu Arg
                 275                 280                 285

 Ile Gly Met Val Val Lys Thr Gly Val Val Pro Gln Leu Val Lys
                 290                 295                 300

 Leu Leu Gly Ala Ser Glu Leu Pro Ile Val Thr Pro Ala Leu Arg
                 305                 310                 315

 Ala Ile Gly Asn Ile Val Thr Gly Thr Asp Glu Gln Thr Gln Val
                 320                 325                 330

 Val Ile Asp Ala Gly Ala Leu Ala Val Phe Pro Ser Leu Leu Thr
                 335                 340                 345

 Asn Pro Lys Thr Asn Ile Gln Lys Glu Ala Thr Trp Thr Met Ser
                 350                 355                 360

 Asn Ile Thr Ala Gly Arg Gln Asp Gln Ile Gln Gln Val Val Asn
                 365                 370                 375

 His Gly Leu Val Pro Phe Leu Val Ser Val Leu Ser Lys Ala Asp
                 380                 385                 390

 Phe Lys Thr Gln Lys Glu Ala Val Trp Ala Val Thr Asn Tyr Thr
                 395                 400                 405

 Ser Gly Gly Thr Val Glu Gln Ile Val Tyr Leu Val His Cys Gly
                 410                 415                 420

 Ile Ile Glu Pro Leu Met Asn Leu Leu Thr Ala Lys Asp Thr Lys
                 425                 430                 435

 Ile Ile Leu Val Ile Leu Asp Ala Ile Ser Asn Ile Phe Gln Ala
                 440                 445                 450

 Ala Glu Lys Leu Gly Glu Thr Glu Lys Leu Ser Ile Met Ile Glu
                 455                 460                 465

 Glu Cys Gly Gly Leu Asp Lys Ile Glu Ala Leu Gln Asn His Glu
                 470                 475                 480

 Asn Glu Ser Val Tyr Lys Ala Ser Leu Ser Leu Ile Glu Lys Tyr
                 485                 490                 495

 Phe Ser Val Glu Glu Glu Glu Asp Gln Asn Val Val Pro Glu Thr
                 500                 505                 510

 Thr Ser Glu Gly Tyr Thr Phe Gln Val Gln Asp Gly Ala Pro Gly
                 515                 520                 525

 Thr Phe Asn Phe


<210> 2443
<211> 3309
<212> DNA
<213> Homo sapien

<400> 2443
 gcggcgcgcc cgagcctagt ccccacgccg cggcgcgccc gggctccctg 50

 ctgatcccag aacaatcaac catgacgacc gaatctggat cagactcgga 100

 atccaagccg gaccaggagg ccgagcccca ggaggcggcg ggggcgcagg 150

 ggcggcgggg gccgtgccgg agccgcccaa ggaggagcag cagcaggccc 200

 tggagcagtt cgccgccgct gcagcgcaca gcaccccggt gcgagggagg 250

 tcactgacaa ggaacaggag tttgctgcca gggctgcaaa acagctcgaa 300

 tatcagcaat tagaagacga taaactttct cagaaatcat ctagcagtaa 350

 actctctcgg tctccattaa agattgtcaa aaagcctaaa agcatgcagt 400

 gcaaagtgat acttctcgat ggatcagaat atacctgtga tgtagagaaa 450

 cgctccagag gacaagtgct gtttgataaa gtgtgtgaac acttgaactt 500

 gctagagaaa gactactttg ggcttacgta tcgagatgct gaaaaccaga 550

 agaattggtt ggaccctgct aaggaaataa aaaaacaggt tcgaagtggt 600

 gcttggcact tttcatttaa tgtgaaattt tatccaccag accctgccca 650

 actatctgaa gatatcacca ggtactacct ctgcttgcag ttgcgagatg 700

 acatcgtgtc cggaaggctg ccctgctcct ttgttaccct ggccttgctg 750

 ggctcctaca ctgtccagtc agagctcgga gactatgacc cagatgaatg 800

 tgggagcgat tacattagtg agttccgctt tgcaccaaac cacactaaag 850

 aactggaaga caaagtgatc gagctgcaca agagccacag aggaatgacg 900

 ccagcagaag cagagatgca tttcttggaa aatgccaaaa aattatcaat 950

 gtatggggta gatttacatc atgctaagga ctcagaaggg gtagaaatta 1000

 tgttaggagt ttgtgcaagt ggtctgttga tatatcgcga ccggctgcga 1050

 ataaacagat ttgcctggcc caaggttcta aagatttcat acaaacggaa 1100

 caacttttac attaagatcc ggccgggaga gtttgaacaa tttgaaagca 1150

 ccattgggtt taagctgcca aaccatcgag ctgccaagcg tttatggaaa 1200

 gtatgtgttg agcatcatac atttttcaga ctactgttac cagaagcacc 1250

 tcccaagaaa ttcctaacct tgggttccaa gtttcgttat agtggcagga 1300

 cacaagcgca aacgagaaga gccagtgcgt tgatagatcg cccagcacct 1350

 tactttgaac gctcatccag caaacgttat accatgtctc gcagcttgga 1400

 tggagcatca gtgaatgaaa accatgaaat atacatgaag gattctatgt 1450

 ctgctgcaga ggttggtact ggccagtacg ccacaacaaa aggcatctct 1500

 cagaccaact tgatcaccac tgtgactccg gagaagaagg ctgaggagga 1550

 gcgggacgag gaagaggaca aacggaggaa gggggaagaa gtcacgccca 1600

 tctcggccat ccagcacgag ggaaagactg acagtgagcg cacggacacc 1650

 gcagccgacg gggagaccac tgccactgag gagctagaaa aaactcaaga 1700

 tgacctgatg aaacatcaaa ccaacattag cgagctgaaa agaaccttct 1750

 tagaaacctc aacagacact gccgtaacga atgaatggga gaagaggctt 1800

 tccacctccc ccgtgcgact ggccgccagg caggaggatg cccccatgat 1850

 cgaaccactt gtccctgaag agaaaatgga aaccaagacg gagtccagtg 1900

 gatagagacg gaacccaccg tgcaccacct gccgcttagc actgagaagg 1950

 tggtgcagga gaccgtgttg gtggaggagc ggcgtgtggt gcacgcgagt 2000

 ggggatgctt cttactcggc gggagacagc ggggatgctg cagcacagcc 2050

 cgcattcaca ggcattaaag ggaaagaggg ctctgcttga cggagggggc 2100

 taaagaggaa ggaggggagg aggtcgctaa agctgtcctg gaacaggaag 2150

 agacagccgc tgcttcccgt gagcgacaag aggagcagag tgcagccatc 2200

 cacatttcag aaactttgga acaaaaacct cattttgagt cctcaacggt 2250

 gaagacggaa accatcagtt ttggcagtgt ttcaccggga ggagtaaagc 2300

 tagaaatttc cacaagaagt gccagtagtt cacaccgaaa ccaaaaccat 2350

 cacatatgaa tcatcacagg tcgatccagg cacagatctg gagccaggcg 2400

 tgctgatgag tgcacagacg atcacatctg aaaccaccag taccaccacc 2450

 actacccaca tcaccaaaac tgtgaaaggg ggcatttcag agacaagaat 2500

 tgagaagcga atagtcatca cgggggatgc agacattgac catgaccagg 2550

 cgctggctca ggcaattaaa gaggccaaag agcagcaccc tgacatgtca 2600

 gtgaccaaag tagtggtcca taaagagaca gagatcacac cagaagatgg 2650

 agaggattga ccagaggaat aacttagctt gcacatgaat gcagtcatgc 2700

 aaaccgttag gaaaaccaga gcctatatgg agttccctct tctaacccaa 2750

 ctgtacttgt atctgtccgt ggaaaatttc agtccagaag aattgacctt 2800

 gaccattaat aaagacactg gcagagagat cttcccataa taaagcaatc 2850

 tgattcagca tcactaaacc gataatgcat gaagcaacga taaaattaca 2900

 aaagagcagc atttttaatt ttcacaaaat gtctcagttt tcagctatac 2950

 ctgctcgttc ataaccaaca atataaaccg tggtctcatg taacacataa 3000

 acaattcatg cctttcatag tttattatta ttaaagtcta aacaaaattg 3050

 caatttctta ggtaacctta tatttacaat aaatgaagat taccctcaaa 3100

 tgctagaagc tgtctaggtc cgtccggtgt gtcagatttc ctcagattag 3150

 atgtgccaat aaccaagttt attcagtaaa caacttgtac ttgtttcatc 3200

 tggtttatta ctctcaccca taaacagtaa tgactctctg accctctgga 3250

 aatatgtaat gcttccaatc ttgctttgtg tatctcattt aatttgttcc 3300

 ggttaagga 3309

<210> 2444
<211> 503
<212> PRT
<213> Homo sapien

<400> 2444
 Met Gln Cys Lys Val Ile Leu Leu Asp Gly Ser Glu Tyr Thr Cys
   1               5                  10                  15

 Asp Val Glu Lys Arg Ser Arg Gly Gln Val Leu Phe Asp Lys Val
                  20                  25                  30

 Cys Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr
                  35                  40                  45

 Tyr Arg Asp Ala Glu Asn Gln Lys Asn Trp Leu Asp Pro Ala Lys
                  50                  55                  60

 Glu Ile Lys Lys Gln Val Arg Ser Gly Ala Trp His Phe Ser Phe
                  65                  70                  75

 Asn Val Lys Phe Tyr Pro Pro Asp Pro Ala Gln Leu Ser Glu Asp
                  80                  85                  90

 Ile Thr Arg Tyr Tyr Leu Cys Leu Gln Leu Arg Asp Asp Ile Val
                  95                 100                 105

 Ser Gly Arg Leu Pro Cys Ser Phe Val Thr Leu Ala Leu Leu Gly
                 110                 115                 120

 Ser Tyr Thr Val Gln Ser Glu Leu Gly Asp Tyr Asp Pro Asp Glu
                 125                 130                 135

 Cys Gly Ser Asp Tyr Ile Ser Glu Phe Arg Phe Ala Pro Asn His
                 140                 145                 150

 Thr Lys Glu Leu Glu Asp Lys Val Ile Glu Leu His Lys Ser His
                 155                 160                 165

 Arg Gly Met Thr Pro Ala Glu Ala Glu Met His Phe Leu Glu Asn
                 170                 175                 180

 Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His His Ala Lys
                 185                 190                 195

 Asp Ser Glu Gly Val Glu Ile Met Leu Gly Val Cys Ala Ser Gly
                 200                 205                 210

 Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala Trp
                 215                 220                 225

 Pro Lys Val Leu Lys Ile Ser Tyr Lys Arg Asn Asn Phe Tyr Ile
                 230                 235                 240

 Lys Ile Arg Pro Gly Glu Phe Glu Gln Phe Glu Ser Thr Ile Gly
                 245                 250                 255

 Phe Lys Leu Pro Asn His Arg Ala Ala Lys Arg Leu Trp Lys Val
                 260                 265                 270

 Cys Val Glu His His Thr Phe Phe Arg Leu Leu Leu Pro Glu Ala
                 275                 280                 285

 Pro Pro Lys Lys Phe Leu Thr Leu Gly Ser Lys Phe Arg Tyr Ser
                 290                 295                 300

 Gly Arg Thr Gln Ala Gln Thr Arg Arg Ala Ser Ala Leu Ile Asp
                 305                 310                 315

 Arg Pro Ala Pro Tyr Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr
                 320                 325                 330

 Met Ser Arg Ser Leu Asp Gly Ala Ser Val Asn Glu Asn His Glu
                 335                 340                 345

 Ile Tyr Met Lys Asp Ser Met Ser Ala Ala Glu Val Gly Thr Gly
                 350                 355                 360

 Gln Tyr Ala Thr Thr Lys Gly Ile Ser Gln Thr Asn Leu Ile Thr
                 365                 370                 375

 Thr Val Thr Pro Glu Lys Lys Ala Glu Glu Glu Arg Asp Glu Glu
                 380                 385                 390

 Glu Asp Lys Arg Arg Lys Gly Glu Glu Val Thr Pro Ile Ser Ala
                 395                 400                 405

 Ile Gln His Glu Gly Lys Thr Asp Ser Glu Arg Thr Asp Thr Ala
                 410                 415                 420

 Ala Asp Gly Glu Thr Thr Ala Thr Glu Glu Leu Glu Lys Thr Gln
                 425                 430                 435

 Asp Asp Leu Met Lys His Gln Thr Asn Ile Ser Glu Leu Lys Arg
                 440                 445                 450

 Thr Phe Leu Glu Thr Ser Thr Asp Thr Ala Val Thr Asn Glu Trp
                 455                 460                 465

 Glu Lys Arg Leu Ser Thr Ser Pro Val Arg Leu Ala Ala Arg Gln
                 470                 475                 480

 Glu Asp Ala Pro Met Ile Glu Pro Leu Val Pro Glu Glu Lys Met
                 485                 490                 495

 Glu Thr Lys Thr Glu Ser Ser Gly
                 500

<210> 2445
<211> 1935
<212> DNA
<213> Homo sapien

<400> 2445
 agaccaagga gtggaaagtt ctccggcagc cctgagatct caagagtgac 50

 atttgtgaga ccagctaatt tgattaaaat tctcttggaa tcagctttgc 100

 tagtatcata cctgtgccag atttcatcat gggaaacagc tgttacaaca 150

 tagtagccac tctgttgctg gtcctcaact ttgagaggac aagatcattg 200

 caggatcctt gtagtaactg cccagctggt acattctgtg ataataacag 250

 gaatcagatt tgcagtccct gtcctccaaa tagtttctcc agcgcaggtg 300

 gacaaaggac ctgtgacata tgcaggcagt gtaaaggtgt tttcaggacc 350

 aggaaggagt gttcctccac cagcaatgca gagtgtgact gcactccagg 400

 gtttcactgc ctgggggcag gatgcagcat gtgtgaacag gattgtaaac 450

 aaggtcaaga actgacaaaa aaaggttgta aagactgttg ctttgggaca 500

 tttaacgatc agaaacgtgg catctgtcga ccctggacaa actgttcttt 550

 ggatggaaag tctgtgcttg tgaatgggac gaaggagagg gacgtggtct 600

 gtggaccatc tccagccgac ctctctccgg gagcatcctc tgtgaccccg 650

 cctgcccctg cgagagagcc aggacactct ccgcagatca tctccttctt 700

 tcttgcgctg acgtcgactg cgttgctctt cctgctgttc ttcctcacgc 750

 tccgtttctc tgttgttaaa cggggcagaa agaaactcct gtatatattc 800

 aaacaaccat ttatgagacc agtacaaact actcaagagg aagatggctg 850

 tagctgccga tttccagaag aagaagaagg aggatgtgaa ctgtgaaatg 900

 gaagtcaata gggctgttgg gactttcttg aaaagaagca aggaaatatg 950

 agtcatccgc tatcacagct ttcaaaagca agaacaccat cctacataat 1000

 acccaggatt cccccaacac acgttctttt ctaaatgcca atgagttggc 1050

 ctttaaaaat gcaccacttt tttttttttt ttgacagggt ctcactctgt 1100

 cacccaggct ggagtgcagt ggcaccacca tggctctctg cagccttgac 1150

 ctctgggagc tcaagtgatc ctcctgcctc agtctcctga gtagctggaa 1200

 ctacaaggaa gggccaccac acctgactaa cttttttgtt ttttgtttgg 1250

 taaagatggc atttcaccat gttgtacagg ctggtctcaa actcctaggt 1300

 tcactttggc ctcccaaagt gctgggatta cagacatgaa ctgccaggcc 1350

 cggccaaaat aatgcaccac ttttaacaga acagacagat gaggacagag 1400

 ctggtgataa aaaaaaaaaa aaaaaagcat tttctagata ccacttaaca 1450

 ggtttgagct agtttttttg aaatccaaag aaaattatag tttaaattca 1500

 attacatagt ccagtggtcc aactataatt ataatcaaaa tcaatgcagg 1550

 tttgtttttt ggtgctaata tgacatatga caataagcca cgaggtgcag 1600

 taagtacccg actaaagttt ccgtgggttc tgtcatgtaa cacgacatgc 1650

 tccaccgtca ggggggagta tgagcagagt gcctgagttt agggtcaagg 1700

 acaaaaaacc tcaggcctgg aggaagtttt ggaaagagtt caagtgtctg 1750

 tatatcctat ggtcttctcc atcctcacac cttctgcctt tgtcctgctc 1800

 ccttttaagc caggttacat tctaaaaatt cttaactttt aacataatat 1850

 tttataccaa agccaataaa tgaactgcat atgaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1935

<210> 2446
<211> 255
<212> PRT
<213> Homo sapien

<400> 2446
 Met Gly Asn Ser Cys Tyr Asn Ile Val Ala Thr Leu Leu Leu Val
   1               5                  10                  15

 Leu Asn Phe Glu Arg Thr Arg Ser Leu Gln Asp Pro Cys Ser Asn
                  20                  25                  30

 Cys Pro Ala Gly Thr Phe Cys Asp Asn Asn Arg Asn Gln Ile Cys
                  35                  40                  45

 Ser Pro Cys Pro Pro Asn Ser Phe Ser Ser Ala Gly Gly Gln Arg
                  50                  55                  60

 Thr Cys Asp Ile Cys Arg Gln Cys Lys Gly Val Phe Arg Thr Arg
                  65                  70                  75

 Lys Glu Cys Ser Ser Thr Ser Asn Ala Glu Cys Asp Cys Thr Pro
                  80                  85                  90

 Gly Phe His Cys Leu Gly Ala Gly Cys Ser Met Cys Glu Gln Asp
                  95                 100                 105

 Cys Lys Gln Gly Gln Glu Leu Thr Lys Lys Gly Cys Lys Asp Cys
                 110                 115                 120

 Cys Phe Gly Thr Phe Asn Asp Gln Lys Arg Gly Ile Cys Arg Pro
                 125                 130                 135

 Trp Thr Asn Cys Ser Leu Asp Gly Lys Ser Val Leu Val Asn Gly
                 140                 145                 150

 Thr Lys Glu Arg Asp Val Val Cys Gly Pro Ser Pro Ala Asp Leu
                 155                 160                 165

 Ser Pro Gly Ala Ser Ser Val Thr Pro Pro Ala Pro Ala Arg Glu
                 170                 175                 180

 Pro Gly His Ser Pro Gln Ile Ile Ser Phe Phe Leu Ala Leu Thr
                 185                 190                 195

 Ser Thr Ala Leu Leu Phe Leu Leu Phe Phe Leu Thr Leu Arg Phe
                 200                 205                 210

 Ser Val Val Lys Arg Gly Arg Lys Lys Leu Leu Tyr Ile Phe Lys
                 215                 220                 225

 Gln Pro Phe Met Arg Pro Val Gln Thr Thr Gln Glu Glu Asp Gly
                 230                 235                 240

 Cys Ser Cys Arg Phe Pro Glu Glu Glu Glu Gly Gly Cys Glu Leu
                 245                 250                 255

<210> 2447
<211> 3171
<212> DNA
<213> Homo sapien

<400> 2447
 gctgcaccaa cttcctgttg ggtgctgtgg tcccaaggcg cgtgctttgc 50

 agcagatgtg tgacctggcg ttcccctgag tgctcggaaa atggccttgt 100

 ctccggtcgt tcccgttcag gagcagaatt ttcccactgt aaaaaaccga 150

 gcaagtctgg ataagtgagg ctggctccat gtatccagaa tcaacgacgg 200

 gctccccggc tcggctctcg ctgcggcaga cgggctcccc cgggatgatc 250

 tacagtactc ggtatgggag tcccaaaaga cagctccagt tttacaggaa 300

 cctgggcaag tctggcctgc gggtctcctg cctgggactt ggaacatggg 350

 tgaccttcgg aggccagatc accgatgaga tggcagagca gctcatgacc 400

 ttggcctatg ataatggcat caacctcttc gatacagcag aagtctacgc 450

 agccggcaag gctgaagtgg tactgggaaa catcattaag aagaaaggat 500

 ggaggcggtc cagcctcgtc atcaccacca agatcttctg gggcggaaag 550

 gcggagacgg agcggggcct gtccaggaag cacataatcg aaggtctgaa 600

 agcttccctg gagcgactgc agctggagta cgtggatgtg gtgtttgcca 650

 accgcccgga ccccaacacc ccgatggaag agaccgtccg cgccatgacc 700

 cacgtcatca accaggggat ggccatgtac tggggcacgt cacgctggag 750

 ctccatggag atcatggagg cctactccgt ggcccggcag ttcaacctga 800

 ccccgcccat ctgcgagcag gctgagtacc acatgttcca gcgtgagaaa 850

 gtggaggtgc agctgccgga gctgttccac aagataggag tgggcgccat 900

 gacctggtcc cctctggcct gtggcattgt ttctggcaag tacgacagtg 950

 gcatcccacc ctactcaaga gcctccttga agggctacca gtggctgaag 1000

 gacaagatcc tcagtgagga gggccggcgc cagcaagcca agctgaagga 1050

 gctgcaggcc atcgccgagc gcctgggctg caccctgccc cagctggcca 1100

 tagcctggtg cctgaggaat gagggagtca gctccgtgct cctgggggcc 1150

 tccaatgcgg accagctcat ggagaacatt ggggcaatac aggtccttcc 1200

 gaaactgtca tcttccatta tccacgagat tgatagtatt ttgggcaata 1250

 aaccctacag caaaaaggac tacagatcct aagccgcccc cgcccgcctg 1300

 ctcggacagt ttccgttccc tcctagtctc tgttcgctcg cttaagctgt 1350

 tttgaagcca agtgaagagt gtggtttgca tccaagagaa aacaccacac 1400

 tgtgatgtca tcgggaaatg atctcccaag tcgctgccag acaccaccca 1450

 ctgcttcgcc ggacaatgtc gaagtccagt ctgtgccggg gaaggcactg 1500

 gttaggaagg atgttcaaac ggtcccaccc aagcctgtca cctctgctca 1550

 tcctccaaga ccacccagct ttctcccagc cacagccaag attcccaaag 1600

 tcaaggccca aagatttcca aggttcccaa agtcaaggcc aggccaaggc 1650

 ctggttgggt ccttggggcg ggcagggcca gcctctcctc tgctgagaat 1700

 ccccacttgg tgtaggggga gaggggaaag gggtctggcc catcgagggg 1750

 ccccttctgc cagggccttg gttgctgggg cagggcctcc ccactggggg 1800

 tcttcctcca cctcccactt tccaagggct ccaggaatct ggggcctgac 1850

 cacagattcc tctcccatcc ttttctgctc caacctgccc cactgggtcc 1900

 cggcaggggc catgcctacc aagctcgagc tggcccttga cccccaccca 1950

 cccccaccct tgctggcagg ggcagggacc ccagggggat tgactctgca 2000

 gtttgggagc cacaaaaagc gtagcggtgt gatttctagc tcagcctccc 2050

 accgtcttcc tcctacacac caatgatgag cctcatgcca gtgaggcccg 2100

 gagcgcttgg gaggggtccc agtggggcag gcccctctgt ctggccaccc 2150

 ctctgtcctg gccccggaag gccctgtggt catgtgctcc tagctgcacg 2200

 gtggctgctg gccacaccac ggcaagtggc agcaggggcc ggccctgtgc 2250

 acaaggatgc actcctctcg gcccctgtag actttctcta aagccgcccg 2300

 ccagcccagg ccgctgctct gcaccgagct ggtgggcttg ggttttgtgg 2350

 agcgcatgct tggacccttt cagtaaggaa gggtctttgg ggttttctgt 2400

 gcccatgact tgggggctgc acccccacag cacccccaca atgtaggaaa 2450

 agacctcagg gaacctctcc ctggaaagac gggcagggct ggttagcccc 2500

 tcccactgcc tgacacctgg gacaggctgg gcagagggga gagagggcag 2550

 gacaggccag agtgacgccc ccgtgcagct tgggccggag ggcaagggat 2600

 gccagtaagt ctgcaggtgc ggggtgccac ctacaggccc aggcctgtgt 2650

 cccaagcagt acccaggctt tgcagaccac gcggggcagg gctccactga 2700

 agccaccccc acccctcgcc agctagctcc atagggaagc ctgtgtctcc 2750

 tgcccccagg gcgcaccctc agtgcaggca cctctgttcc cgctttgccc 2800

 ctggaggagc cactattcca gaaggctcca ccctgccgtc ctgcgggagc 2850

 ctgctgtcca gtcctggccg ggccaaggcc tgggaaactg tgaaagtcag 2900

 aaaggccagc ggggagaggc tggggcgagg ggaggagggg gatcagcttc 2950

 tgctattacc gacccccctt catgctgccc ctggcgccta gaacccttgc 3000

 ccctcctcat agaccaagtc ccgggggtct ccactcagtc ctgctgcctg 3050

 cttcaccaga agcagccctg tgagtgtggg gtggggaagt cccttcccaa 3100

 cggaggtccc agcctatggc cctgggccca ggtgggggtc gcctgcttcc 3150

 ttcccggaca gggtcctgca g 3171

<210> 2448
<211> 367
<212> PRT
<213> Homo sapien

<400> 2448
 Met Tyr Pro Glu Ser Thr Thr Gly Ser Pro Ala Arg Leu Ser Leu
   1               5                  10                  15

 Arg Gln Thr Gly Ser Pro Gly Met Ile Tyr Ser Thr Arg Tyr Gly
                  20                  25                  30

 Ser Pro Lys Arg Gln Leu Gln Phe Tyr Arg Asn Leu Gly Lys Ser
                  35                  40                  45

 Gly Leu Arg Val Ser Cys Leu Gly Leu Gly Thr Trp Val Thr Phe
                  50                  55                  60

 Gly Gly Gln Ile Thr Asp Glu Met Ala Glu Gln Leu Met Thr Leu
                  65                  70                  75

 Ala Tyr Asp Asn Gly Ile Asn Leu Phe Asp Thr Ala Glu Val Tyr
                  80                  85                  90

 Ala Ala Gly Lys Ala Glu Val Val Leu Gly Asn Ile Ile Lys Lys
                  95                 100                 105

 Lys Gly Trp Arg Arg Ser Ser Leu Val Ile Thr Thr Lys Ile Phe
                 110                 115                 120

 Trp Gly Gly Lys Ala Glu Thr Glu Arg Gly Leu Ser Arg Lys His
                 125                 130                 135

 Ile Ile Glu Gly Leu Lys Ala Ser Leu Glu Arg Leu Gln Leu Glu
                 140                 145                 150

 Tyr Val Asp Val Val Phe Ala Asn Arg Pro Asp Pro Asn Thr Pro
                 155                 160                 165

 Met Glu Glu Thr Val Arg Ala Met Thr His Val Ile Asn Gln Gly
                 170                 175                 180

 Met Ala Met Tyr Trp Gly Thr Ser Arg Trp Ser Ser Met Glu Ile
                 185                 190                 195

 Met Glu Ala Tyr Ser Val Ala Arg Gln Phe Asn Leu Thr Pro Pro
                 200                 205                 210

 Ile Cys Glu Gln Ala Glu Tyr His Met Phe Gln Arg Glu Lys Val
                 215                 220                 225

 Glu Val Gln Leu Pro Glu Leu Phe His Lys Ile Gly Val Gly Ala
                 230                 235                 240

 Met Thr Trp Ser Pro Leu Ala Cys Gly Ile Val Ser Gly Lys Tyr
                 245                 250                 255

 Asp Ser Gly Ile Pro Pro Tyr Ser Arg Ala Ser Leu Lys Gly Tyr
                 260                 265                 270

 Gln Trp Leu Lys Asp Lys Ile Leu Ser Glu Glu Gly Arg Arg Gln
                 275                 280                 285

 Gln Ala Lys Leu Lys Glu Leu Gln Ala Ile Ala Glu Arg Leu Gly
                 290                 295                 300

 Cys Thr Leu Pro Gln Leu Ala Ile Ala Trp Cys Leu Arg Asn Glu
                 305                 310                 315

 Gly Val Ser Ser Val Leu Leu Gly Ala Ser Asn Ala Asp Gln Leu
                 320                 325                 330

 Met Glu Asn Ile Gly Ala Ile Gln Val Leu Pro Lys Leu Ser Ser
                 335                 340                 345

 Ser Ile Ile His Glu Ile Asp Ser Ile Leu Gly Asn Lys Pro Tyr
                 350                 355                 360

 Ser Lys Lys Asp Tyr Arg Ser
                 365

<210> 2449
<211> 2008
<212> DNA
<213> Homo sapien

<400> 2449
 atggcgtagt ccccaaagaa cgaggaccta gtaacataat tgtgcttcat 50

 tatggtcctt tcccggcctt ctctctcaca catacacaga gcccctacca 100

 ggaccagaca gctctcagag caaccctagc cccattacct cttccctttc 150

 cagaggacct gaaaaacgtg ttcccacccg aggtcgctgt gtttgagcca 200

 tcagaagcag agatctccca cacccaaaag gccacactgg tgtgcctggc 250

 cacaggcttc taccccgacc acgtggagct gagctggtgg gtgaatggga 300

 aggaggtgca cagtggggtc agcacagacc cgcagcccct caaggagcag 350

 cccgccctca atgactccag atactgcctg agcagccgcc tgagggtctc 400

 ggccaccttc tggcagaacc cccgcaacca cttccgctgt caagtccagt 450

 tctacgggct ctcggagaat gacgagtgga cccaggatag ggccaaacct 500

 gtcacccaga tcgtcagcgc cgaggcctgg ggtagagcag gtgagtgggg 550

 cctggggaga tgcctggagg agattaggtg agaccagcta ccagggaaaa 600

 tggaaagatc caggtagcgg acaagactag atccagaaga aagccagagt 650

 ggacaaggtg ggatgatcaa ggttcacagg gtcagcaaag cacggtgtgc 700

 acttccccca ccaagaagca tagaggctga atggagcacc tcaagctcat 750

 tcttccttca gatcctgaca ccttagagct aagctttcaa gtctccctga 800

 ggaccagcca tacagctcag catctgagtg gtgtgcatcc cattctcttc 850

 tggggtcctg gtttcctaag atcatagtga ccacttcgct ggcactggag 900

 cagcatgagg gagacagaac cagggctatc aaaggaggct gactttgtac 950

 tatctgatat gcatgtgttt gtggcctgtg agtctgtgat gtaaggctca 1000

 atgtccttac aaagcagcat tctctcatcc atttttcttc ccctgttttc 1050

 tttcagactg tggcttcacc tccggtaagt gagtctctcc tttttctctc 1100

 tatctttcgc cgtctctgct ctcgaaccag ggcatggaga atccacggac 1150

 acaggggcgt gagggaggcc agagccacct gtgcacaggt acctacatgc 1200

 tctgttcttg tcaacagagt cttaccagca aggggtcctg tctgccacca 1250

 tcctctatga gatcttgcta gggaaggcca ccttgtatgc cgtgctggtc 1300

 agtgccctcg tgctgatggc catggtaagg aggagggtgg gatagggcag 1350

 atgatggggg caggggatgg aacatcacac atgggcataa aggaatctca 1400

 gagccagagc acagcctaat atatcctatc acctcaatga aaccataatg 1450

 aagccagact ggggagaaaa tgcagggaat atcacagaat gcatcatggg 1500

 aggatggaga caaccagcga gccctactca aattaggcct cagagcccgc 1550

 ctcccctgcc ctactcctgc tgtgccatag cccctgaaac cctgaaaatg 1600

 ttctctcttc cacaggtcaa gagaaaggat tccagaggct agctccaaaa 1650

 ccatcccagg tcattcttca tcctcaccca ggattctcct gtacctgctc 1700

 ccaatctgtg ttcctaaaag tgattctcac tctgcttctc atctcctact 1750

 tacatgaata cttctctctt ttttctgttt ccctgaagat tgagctccca 1800

 acccccaagt acgaaatagg ctaaaccaat aaaaaattgt gtgttgggcc 1850

 tggttgcatt tcaggagtgt ctgtggagtt ctgctcatca ctgacctatc 1900

 ttctgattta gggaaagcag cattcgcttg gacatctgaa gtgacagccc 1950

 tctttctctc cacccaatgc tgctttctcc tgttcatcct gatggaagtc 2000

 tcaacaca 2008

<210> 2450
<211> 178
<212> PRT
<213> Homo sapien

<400> 2450
 Asp Leu Lys Asn Val Phe Pro Pro Glu Val Ala Val Phe Glu Pro
   1               5                  10                  15

 Ser Glu Ala Glu Ile Ser His Thr Gln Lys Ala Thr Leu Val Cys
                  20                  25                  30

 Leu Ala Thr Gly Phe Tyr Pro Asp His Val Glu Leu Ser Trp Trp
                  35                  40                  45

 Val Asn Gly Lys Glu Val His Ser Gly Val Ser Thr Asp Pro Gln
                  50                  55                  60

 Pro Leu Lys Glu Gln Pro Ala Leu Asn Asp Ser Arg Tyr Cys Leu
                  65                  70                  75

 Ser Ser Arg Leu Arg Val Ser Ala Thr Phe Trp Gln Asn Pro Arg
                  80                  85                  90

 Asn His Phe Arg Cys Gln Val Gln Phe Tyr Gly Leu Ser Glu Asn
                  95                 100                 105

 Asp Glu Trp Thr Gln Asp Arg Ala Lys Pro Val Thr Gln Ile Val
                 110                 115                 120

 Ser Ala Glu Ala Trp Gly Arg Ala Asp Cys Gly Phe Thr Ser Glu
                 125                 130                 135

 Ser Tyr Gln Gln Gly Val Leu Ser Ala Thr Ile Leu Tyr Glu Ile
                 140                 145                 150

 Leu Leu Gly Lys Ala Thr Leu Tyr Ala Val Leu Val Ser Ala Leu
                 155                 160                 165

 Val Leu Met Ala Met Val Lys Arg Lys Asp Ser Arg Gly
                 170                 175

<210> 2451
<211> 2226
<212> DNA
<213> Homo sapien

<400> 2451
 ggaagcaggg cggggcctct ggtggcggtc gggaactcgg tgggaggcgg 50

 caacattgtt tcaagttggc caaattgaca agagcgagag gtatactgcg 100

 ttccatcccg acccggggcc acggtactgg gccctgtttc cccctcctcg 150

 gcccccgaga gccagggtcc gccttctgca gggttcccag gcccccgctc 200

 cagggccggg ctgacccgac tcgctggcgc ttcatggaga acttccaaaa 250

 ggtggaaaag atcggagagg gcacgtacgg agttgtgtac aaagccagaa 300

 acaagttgac gggagaggtg gtggcgctta agaaaatccg cctggacact 350

 gagactgagg gtgtgcccag tactgccatc cgagagatct ctctgcttaa 400

 ggagcttaac catcctaata ttgtcaagct gctggatgtc attcacacag 450

 aaaataaact ctacctggtt tttgaatttc tgcaccaaga tctcaagaaa 500

 ttcatggatg cctctgctct cactggcatt cctcttcccc tcatcaagag 550

 ctatctgttc cagctgctcc agggcctagc tttctgccat tctcatcggg 600

 tcctccaccg agaccttaaa cctcagaatc tgcttattaa cacagagggg 650

 gccatcaagc tagcagactt tggactagcc agagcttttg gagtccctgt 700

 tcgtacttac acccatgagg tgactcgccg ggccctattc cctggagatt 750

 ctgagattga ccagctcttc cggatctttc ggactctggg gaccccagat 800

 gaggtggtgt ggccaggagt tacttctatg cctgattaca agccaagttt 850

 ccccaagtgg gcccggcaag attttagtaa agttgtacct cccctggatg 900

 aagatggacg gagcttgtta tcgcaaatgc tgcactacga cccttacaag 950

 aggatttcgg ccaaggcagc cctggctcac cctttcttcc aggatgtgac 1000

 caagccagta ccccatcttc gactctgata gccttcttga agcccccagc 1050

 cctaatctca ccctctcctc cagtgtgggc ttgaccaggc ttggccttgg 1100

 gctatttgga ctcaggtggg ccctctgaac ttgccttaaa cactcacctt 1150

 ctagtcttgg ccagccaact ctgggaatac aggggtgaaa ggggggaacc 1200

 agtgaaaatg aaaggaagtt tcagtattag atgcacttaa gttagcctcc 1250

 accacccttt cccccttctc ttagttattg ctgaagaggg ttggtataaa 1300

 aataatttta aaaaagcctt cctacacgtt agatttgccg taccaatctc 1350

 tgaatgcccc ataattatta tttccagtgt ttgggatgac caggatccca 1400

 agcctcctgc tgccacaatg tttataaagg ccaaatgata gcgggggcta 1450

 agttggtgct tttgagaacc aagtaaaaca aaaccactgg gaggagtcta 1500

 ttttaaagaa ttcggttgaa aaaatagatc caatcagttt ataccctagt 1550

 tagtgttttg cctcacctaa taggctggga gactgaagac tcagcccggg 1600

 tggggctgca gaaaaatgat tggccccagt ccccttgttt gtcccttcta 1650

 caggcatgag gaatctggga ggccctgaga cagggattgt gcttcattcc 1700

 aatctattgc ttcaccatgg ccttatgagg caggtgagag atgtttgaat 1750

 ttttctcttc cttttagtat tcttagttgt tcagttgcca aggatccctg 1800

 atcccatttt cctctgacgt ccacctccta ccccatagga gttagaagtt 1850

 agggtttagg catcattttg agaatgctga cactttttca gggctgtgat 1900

 tgagtgaggg catgggtaaa aatatttctt taaaagaagg atgaacaatt 1950

 atatttatat ttcaggttat atccaatagt agagttggct tttttttttt 2000

 tttttttggt catagtgggt ggatttgttg ccatgtgcac cttggggttt 2050

 tgtaatgaca gtgctaaaaa aaaaaaagca ttttttttta tgatttgtct 2100

 ctgtcaccct tgtccttgag tgctcttgct attaacgtta tttgtaattt 2150

 agtttgtagc tcattaaaaa aatgtgccta gttttataaa aaaaaaaaaa 2200

 aaaaaaaaaa aaaaaaaaaa aaaaaa 2226

<210> 2452
<211> 264
<212> PRT
<213> Homo sapien

<400> 2452
 Met Glu Asn Phe Gln Lys Val Glu Lys Ile Gly Glu Gly Thr Tyr
   1               5                  10                  15

 Gly Val Val Tyr Lys Ala Arg Asn Lys Leu Thr Gly Glu Val Val
                  20                  25                  30

 Ala Leu Lys Lys Ile Arg Leu Asp Thr Glu Thr Glu Gly Val Pro
                  35                  40                  45

 Ser Thr Ala Ile Arg Glu Ile Ser Leu Leu Lys Glu Leu Asn His
                  50                  55                  60

 Pro Asn Ile Val Lys Leu Leu Asp Val Ile His Thr Glu Asn Lys
                  65                  70                  75

 Leu Tyr Leu Val Phe Glu Phe Leu His Gln Asp Leu Lys Lys Phe
                  80                  85                  90

 Met Asp Ala Ser Ala Leu Thr Gly Ile Pro Leu Pro Leu Ile Lys
                  95                 100                 105

 Ser Tyr Leu Phe Gln Leu Leu Gln Gly Leu Ala Phe Cys His Ser
                 110                 115                 120

 His Arg Val Leu His Arg Asp Leu Lys Pro Gln Asn Leu Leu Ile
                 125                 130                 135

 Asn Thr Glu Gly Ala Ile Lys Leu Ala Asp Phe Gly Leu Ala Arg
                 140                 145                 150

 Ala Phe Gly Val Pro Val Arg Thr Tyr Thr His Glu Val Thr Arg
                 155                 160                 165

 Arg Ala Leu Phe Pro Gly Asp Ser Glu Ile Asp Gln Leu Phe Arg
                 170                 175                 180

 Ile Phe Arg Thr Leu Gly Thr Pro Asp Glu Val Val Trp Pro Gly
                 185                 190                 195

 Val Thr Ser Met Pro Asp Tyr Lys Pro Ser Phe Pro Lys Trp Ala
                 200                 205                 210

 Arg Gln Asp Phe Ser Lys Val Val Pro Pro Leu Asp Glu Asp Gly
                 215                 220                 225

 Arg Ser Leu Leu Ser Gln Met Leu His Tyr Asp Pro Tyr Lys Arg
                 230                 235                 240

 Ile Ser Ala Lys Ala Ala Leu Ala His Pro Phe Phe Gln Asp Val
                 245                 250                 255

 Thr Lys Pro Val Pro His Leu Arg Leu
                 260

<210> 2453
<211> 3986
<212> DNA
<213> Homo sapien

<400> 2453
 atgctgggga agagccatgg taggaccact catggccctc ttcctttggc 50

 ggaccttgga atccaccttc cctgcgttaa agtgctccac caggtgacgc 100

 cggaagagaa gccagcaggc ggcggcggcg tcagcatcag cggcctcctg 150

 cccgtatcta tcgtggcggc gacgggaccc gcctccctgg gcgccggagt 200

 catgtgaccc acacaatggc tgagtggcta ctctcggctt cctggcaacg 250

 ccgagcgaaa gctatgactg cggccgcggg ttcggcgggc cgcgccgcgg 300

 tgcccttgct gctgtgtgcg ctgctggcgc ccggcggcgc gtacgtgctc 350

 gacgactccg acgggctggg ccgggagttc gacggcatcg gcgcggtcag 400

 cggcggcggg gcaacctccc gacttctagt aaattaccca gagccctatc 450

 gttctcagat attggattat ctctttaagc cgaattttgg tgcctctttg 500

 catattttaa aagtggaaat aggtggtgat gggcagacaa cagacggcac 550

 tgagccctcc cacatgcatt atgcactaga tgagaattat ttccgaggat 600

 acgagtggtg gttgatgaaa gaagctaaga agaggaatcc caatattaca 650

 ctcattgggt tgccatggtc attccctgga tggctgggaa aaggtttcga 700

 ctggccttat gtcaatcttc agctgactgc ctattatgtc gtgacctgga 750

 ttgtgggcgc caagcgttac catgatttgg acattgatta tattggaatt 800

 tggaatgaga ggtcatataa tgccaattat attaagatat taagaaaaat 850

 gctgaattat caaggtctcc agcgagtgaa aatcatagca agtgataatc 900

 tctgggagtc catctctgca tccatgctcc ttgatgccga actcttcaag 950

 gtggttgatg ttataggggc tcattatcct ggaacccatt cagcaaaaga 1000

 tgcaaagttg actgggaaga agctttggtc ttctgaagac tttagcactt 1050

 taaatagtga catgggtgca ggctgctggg gtcgcatttt aaatcagaat 1100

 tatatcaatg gctatatgac ttccacaatc gcatggaatt tagtggctag 1150

 ttactatgaa cagttgcctt atgggagatg cgggttgatg acggcccaag 1200

 agccatggag tgggcactac gtggtagaat ctcctgtctg ggtatcagct 1250

 cataccactc agtttactca acctggctgg tattacctga agacagttgg 1300

 ccatttagag aaaggaggaa gctacgtagc tctgactgat ggcttaggga 1350

 acctcaccat catcattgaa accatgagtc ataaacattc taagtgcata 1400

 cggccatttc ttccttattt caatgtgtca caacaatttg ccacctttgt 1450

 tcttaaggga tcttttagtg aaataccaga gctacaggta tggtatacca 1500

 aacttggaaa aacatccgaa agatttcttt ttaagcagct ggattctcta 1550

 tggctccttg acagcgatgg cagtttcaca ctgagcctgc atgaagatga 1600

 gctgttcaca ctcaccactc tcaccactgg tcgcaaaggc agctacccgc 1650

 ttcctccaaa atcccagccc ttcccaagta cctataagga tgatttcaat 1700

 gttgattacc cattttttag tgaagctcca aactttgctg atcaaactgg 1750

 tgtatttgaa tattttacaa atattgaaga ccctggcgag catcacttca 1800

 cgctacgcca agttctcaac cagagaccca ttacgtgggc tgccgatgca 1850

 tccaacacaa tcagtattat aggagactac aactggacca atctgactat 1900

 aaagtgtgat gtttacatag agacccctga cacaggaggt gtgttcattg 1950

 caggaagagt aaataaaggt ggtattttga ttagaagtgc cagaggaatt 2000

 ttcttctgga tttttgcaaa tggatcttac agggttacag gtgatttagc 2050

 tggatggatt atatatgctt taggacgtgt tgaagttaca gcaaaaaaat 2100

 ggtatacact cacgttaact attaagggtc atttcgcctc tggcatgctg 2150

 aatgacaagt ctctgtggac agacatccct gtgaattttc caaagaatgg 2200

 ctgggctgca attggaactc actcctttga atttgcacag tttgacaact 2250

 ttcttgtgga agccacacgc taatacttaa cagggcatca tagaatactc 2300

 tggattttct tcccttcttt ttggttttgg ttcagagcca attcttgttt 2350

 cattggaaca gtatatgagg cttttgagac taaaaataat gaagagtaaa 2400

 aggggagaga aatttatttt taatttaccc tgtggaagat tttattagaa 2450

 ttaattccaa ggggaaaact ggtgaatctt taacattacc tggtgtgttc 2500

 cctaacattc aaactgtgca ttggccatac ccttaggagt ggtttgagta 2550

 gtacagacct cgaagccttg ctgctaacac tgaggtagct ctcttcatct 2600

 tatttgcaag cggtcctgta gatggcagta acttgatcat cactgagatg 2650

 tatttatgca tgctgaccgt gtgtccaagt gagccagtgt cttcatcaca 2700

 agatgatgct gccataatag aaagctgaag aacactagaa gtagcttttt 2750

 gaaaaccact tcaacctgtt atgctttatg ctctaaaaag tattttttta 2800

 ttttcctttt taagatgata cttttgaaat gcaggatatg atgagtggga 2850

 tgattttaaa aacgcctctt taataaacta cctctaacac tatttctgcg 2900

 gtaatagata ttagcagatt aattgggtta tttgcattat ttaatttttt 2950

 tgattccaag ttttggtctt gtaaccacta taactctctg tgaacgtttt 3000

 tccaggtggc tggaagaagg aagaaaacct gatatagcca atgctgttgt 3050

 agtcgtttcc tcagcctcat ctcactgtgc tgtggtctgt cctcacatgt 3100

 gcactggtaa cagactcaca cagctgatga atgcttttct ctccttatgt 3150

 gtggaaggag gggagcactt agacatttgc taactcccag aattggatca 3200

 tctcctaaga tgtacttact ttttaaagtc caaatatgtt tatatttaaa 3250

 tatacgtgag catgttcatc atgttgtatg atttatacta agcattaatg 3300

 tggctctatg tagcaaatca gttattcatg taggtaaagt aaatctagaa 3350

 ttatttataa gaattactca ttgaactaat tctactattt aggaatttat 3400

 aagagtctaa cataggctta gctacagtga agttttgcat tgcttttgaa 3450

 gacaagaaaa gtgctagaat aaataagatt acagagaaaa ttttttgtta 3500

 aaaccaagtg atttccagct gatgtatcta atatttttta aaacaaacat 3550

 tatagaggtg taatttattt acaataaaat gttcctactt taaatataca 3600

 attcagtgag ttttgataaa ttgatatacc catgtaacca acactccagt 3650

 caagcttcag aatatttcca tcaccccaga aggttctctt gtatacctgc 3700

 tcagtcagtt cctttcactc ccaattgttg gcagccattg ataggaattc 3750

 tatcactata ggttagtttt ctttgttcca gaacatcatg aaagcggcgt 3800

 catgtactgt gtattcttat gaatggtttc tttccatcag cataatgatt 3850

 tgagattggt ccatgttgtg tgattcagtg gtttgttcct tcttatttct 3900

 gaagagtttt ccattgtatg aatataccac aatttgtttc ctccccacca 3950

 gtttctgata ctacaattaa aactgtctac atttac 3986

<210> 2454
<211> 669
<212> PRT
<213> Homo sapien

<400> 2454
 Met Thr Ala Ala Ala Gly Ser Ala Gly Arg Ala Ala Val Pro Leu
   1               5                  10                  15

 Leu Leu Cys Ala Leu Leu Ala Pro Gly Gly Ala Tyr Val Leu Asp
                  20                  25                  30

 Asp Ser Asp Gly Leu Gly Arg Glu Phe Asp Gly Ile Gly Ala Val
                  35                  40                  45

 Ser Gly Gly Gly Ala Thr Ser Arg Leu Leu Val Asn Tyr Pro Glu
                  50                  55                  60

 Pro Tyr Arg Ser Gln Ile Leu Asp Tyr Leu Phe Lys Pro Asn Phe
                  65                  70                  75

 Gly Ala Ser Leu His Ile Leu Lys Val Glu Ile Gly Gly Asp Gly
                  80                  85                  90

 Gln Thr Thr Asp Gly Thr Glu Pro Ser His Met His Tyr Ala Leu
                  95                 100                 105

 Asp Glu Asn Tyr Phe Arg Gly Tyr Glu Trp Trp Leu Met Lys Glu
                 110                 115                 120

 Ala Lys Lys Arg Asn Pro Asn Ile Thr Leu Ile Gly Leu Pro Trp
                 125                 130                 135

 Ser Phe Pro Gly Trp Leu Gly Lys Gly Phe Asp Trp Pro Tyr Val
                 140                 145                 150

 Asn Leu Gln Leu Thr Ala Tyr Tyr Val Val Thr Trp Ile Val Gly
                 155                 160                 165

 Ala Lys Arg Tyr His Asp Leu Asp Ile Asp Tyr Ile Gly Ile Trp
                 170                 175                 180

 Asn Glu Arg Ser Tyr Asn Ala Asn Tyr Ile Lys Ile Leu Arg Lys
                 185                 190                 195

 Met Leu Asn Tyr Gln Gly Leu Gln Arg Val Lys Ile Ile Ala Ser
                 200                 205                 210

 Asp Asn Leu Trp Glu Ser Ile Ser Ala Ser Met Leu Leu Asp Ala
                 215                 220                 225

 Glu Leu Phe Lys Val Val Asp Val Ile Gly Ala His Tyr Pro Gly
                 230                 235                 240

 Thr His Ser Ala Lys Asp Ala Lys Leu Thr Gly Lys Lys Leu Trp
                 245                 250                 255

 Ser Ser Glu Asp Phe Ser Thr Leu Asn Ser Asp Met Gly Ala Gly
                 260                 265                 270

 Cys Trp Gly Arg Ile Leu Asn Gln Asn Tyr Ile Asn Gly Tyr Met
                 275                 280                 285

 Thr Ser Thr Ile Ala Trp Asn Leu Val Ala Ser Tyr Tyr Glu Gln
                 290                 295                 300

 Leu Pro Tyr Gly Arg Cys Gly Leu Met Thr Ala Gln Glu Pro Trp
                 305                 310                 315

 Ser Gly His Tyr Val Val Glu Ser Pro Val Trp Val Ser Ala His
                 320                 325                 330

 Thr Thr Gln Phe Thr Gln Pro Gly Trp Tyr Tyr Leu Lys Thr Val
                 335                 340                 345

 Gly His Leu Glu Lys Gly Gly Ser Tyr Val Ala Leu Thr Asp Gly
                 350                 355                 360

 Leu Gly Asn Leu Thr Ile Ile Ile Glu Thr Met Ser His Lys His
                 365                 370                 375

 Ser Lys Cys Ile Arg Pro Phe Leu Pro Tyr Phe Asn Val Ser Gln
                 380                 385                 390

 Gln Phe Ala Thr Phe Val Leu Lys Gly Ser Phe Ser Glu Ile Pro
                 395                 400                 405

 Glu Leu Gln Val Trp Tyr Thr Lys Leu Gly Lys Thr Ser Glu Arg
                 410                 415                 420

 Phe Leu Phe Lys Gln Leu Asp Ser Leu Trp Leu Leu Asp Ser Asp
                 425                 430                 435

 Gly Ser Phe Thr Leu Ser Leu His Glu Asp Glu Leu Phe Thr Leu
                 440                 445                 450

 Thr Thr Leu Thr Thr Gly Arg Lys Gly Ser Tyr Pro Leu Pro Pro
                 455                 460                 465

 Lys Ser Gln Pro Phe Pro Ser Thr Tyr Lys Asp Asp Phe Asn Val
                 470                 475                 480

 Asp Tyr Pro Phe Phe Ser Glu Ala Pro Asn Phe Ala Asp Gln Thr
                 485                 490                 495

 Gly Val Phe Glu Tyr Phe Thr Asn Ile Glu Asp Pro Gly Glu His
                 500                 505                 510

 His Phe Thr Leu Arg Gln Val Leu Asn Gln Arg Pro Ile Thr Trp
                 515                 520                 525

 Ala Ala Asp Ala Ser Asn Thr Ile Ser Ile Ile Gly Asp Tyr Asn
                 530                 535                 540

 Trp Thr Asn Leu Thr Ile Lys Cys Asp Val Tyr Ile Glu Thr Pro
                 545                 550                 555

 Asp Thr Gly Gly Val Phe Ile Ala Gly Arg Val Asn Lys Gly Gly
                 560                 565                 570

 Ile Leu Ile Arg Ser Ala Arg Gly Ile Phe Phe Trp Ile Phe Ala
                 575                 580                 585

 Asn Gly Ser Tyr Arg Val Thr Gly Asp Leu Ala Gly Trp Ile Ile
                 590                 595                 600

 Tyr Ala Leu Gly Arg Val Glu Val Thr Ala Lys Lys Trp Tyr Thr
                 605                 610                 615

 Leu Thr Leu Thr Ile Lys Gly His Phe Ala Ser Gly Met Leu Asn
                 620                 625                 630

 Asp Lys Ser Leu Trp Thr Asp Ile Pro Val Asn Phe Pro Lys Asn
                 635                 640                 645

 Gly Trp Ala Ala Ile Gly Thr His Ser Phe Glu Phe Ala Gln Phe
                 650                 655                 660

 Asp Asn Phe Leu Val Glu Ala Thr Arg
                 665

<210> 2455
<211> 4083
<212> DNA
<213> Homo sapien

<400> 2455
 atggcgagcg actccccggc tcgaagcctg gatgaaatag atctctcggc 50

 tctgagggac cctgcaggga tctttgaatt ggtggaactt gttggaaatg 100

 gaacatacgg gcaagtttat aagggtcgtc atgtcaaaac gggccagctt 150

 gcagccatca aggttatgga tgtcacaggg gatgaagagg aagaaatcaa 200

 acaagaaatt aacatgttga agaaatattc tcatcaccgg aatattgcta 250

 catactatgg tgcttttatc aaaaagaacc caccaggcat ggatgaccaa 300

 ctttggttgg tgatggagtt ttgtggtgct ggctctgtca ccgacctgat 350

 caagaacaca aaaggtaaca cgttgaaaga ggagtggatt gcatacatct 400

 gcagggaaat cttacggggg ctgagtcacc tgcaccagca taaagtgatt 450

 catcgagata ttaaagggca aaatgtcttg ctgactgaaa atgcagaagt 500

 taaactagtg gactttggag tcagtgctca gcttgatcga acagtgggca 550

 ggaggaatac tttcattgga actccctact ggatggcacc agaagttatt 600

 gcctgtgatg aaaacccaga tgccacatat gatttcaaga gtgacttgtg 650

 gtctttgggt atcaccgcca ttgaaatggc agaaggtgct ccccctctct 700

 gtgacatgca ccccatgaga gctctcttcc tcatcccccg gaatccagcg 750

 cctcggctga agtctaagaa gtggtcaaaa aaattccagt catttattga 800

 gagctgcttg gtaaagaatc acagccagcg accagcaaca gaacaattga 850

 tgaagcatcc atttatacga gaccaaccta atgagcgaca ggtccgcatt 900

 caactcaagg accatattga tagaacaaag aagaagcgag gagaaaaaga 950

 tgagacagag tatgagtaca gtggaagtga ggaagaagag gaggagaatg 1000

 actcaggaga gcccagctcc atcctgaatc tgccagggga gtcgacgctg 1050

 cggagggact ttctgaggct gcagctggcc aacaaggagc gttctgaggc 1100

 cctacggagg cagcagctgg agcagcagca gcgggagaat gaggagcaca 1150

 agcggcagct gctggccgag cgtcagaagc gcatcgagga gcagaaagag 1200

 cagaggcggc ggctggagga gcaacaaagg cgagagaagg agctgcggaa 1250

 gcagcaggag agggagcagc gccggcacta tgaggagcag atgcgccggg 1300

 aggaggagag gaggcgtgcg gagcatgaac aggaatacat caggcgacag 1350

 ttagaggagg agcagagaca gttagagatc ttgcagcagc agctactgca 1400

 tgaacaagct ctacttctgg aatataagcg caaacaattg gaagaacaga 1450

 gacaagcaga aagactgcag aggcagctaa agcaagaaag agactactta 1500

 gtttcccttc agcatcagcg gcaggagcag aggcctgtgg agaagaagcc 1550

 actgtaccat tacaaagaag gaatgagtcc tagtgagaag ccagcatggg 1600

 ccaaggaggt agaagaacgg tcaaggctca accggcaaag ttcccctgcc 1650

 atgcctcaca aggttgccaa caggatatct gaccccaacc tgcccccaag 1700

 gtcggagtcc ttcagcatta gtggagttca gcctgctcga acacccccca 1750

 tgctcagacc agtcgatccc cagatcccac atctggtagc tgtaaaatcc 1800

 cagggacctg ccttgaccgc ctcccagtca gtgcacgagc agcccacaaa 1850

 gggcctctct gggtttcagg aggctctgaa cgtgacctcc caccgcgtgg 1900

 agatgccacg ccagaactca gatcccacct cggaaaatcc tcctctcccc 1950

 actcgcattg aaaagtttga ccgaagctct tggttacgac aggaagaaga 2000

 cattccacca aaggtgcctc aaagaacaac ttctatatcc ccagcattag 2050

 ccagaaagaa ttctcctggg aatggtagtg ctctgggacc cagactagga 2100

 tctcaaccca tcagagcaag caaccctgat ctccggagaa ctgagcccat 2150

 cttggagagc cccttgcaga ggaccagcag tggcagttcc tccagctcca 2200

 gcacccctag ctcccagccc agctcccaag gaggctccca gcctggatca 2250

 caagcaggat ccagtgaacg caccagagtt cgagccaaca gtaagtcaga 2300

 aggatcacct gtgcttcccc atgagcctgc caaggtgaaa ccagaagaat 2350

 ccagggacat tacccggccc agtcgaccag ctagctacaa aaaagctata 2400

 gatgaggatc tgacggcatt agccaaagaa ctaagagaac tccggattga 2450

 agaaacaaac cgcccaatga agaaggtgac tgattactcc tcctccagtg 2500

 aggagtcaga aagtagcgag gaagaggagg aagatggaga gagcgagacc 2550

 catgatggga cagtggctgt cagcgacata cccagactga taccaacagg 2600

 agctccaggc agcaacgagc agtacaatgt gggaatggtg gggacgcatg 2650

 ggctggagac ctctcatgcg gacagtttca gcggcagtat ttcaagagaa 2700

 ggaaccttga tgattagaga gacgtctgga gagaagaagc gatctggcca 2750

 cagtgacagc aatggctttg ctggccacat caacctccct gacctggtgc 2800

 agcagagcca ttctccagct ggaaccccga ctgagggact ggggcgcgtc 2850

 tcaacccatt cccaggagat ggactctggg actgaatatg gcatggggag 2900

 cagcaccaaa gcctccttca ccccctttgt ggaccccaga gtataccaga 2950

 cgtctcccac tgatgaagat gaagaggatg aggaatcatc agccgcagct 3000

 ctgtttacta gcgaacttct taggcaagaa caggccaaac tcaatgaagc 3050

 aagaaagatt tcggtggtaa atgtaaaccc aaccaacatt cggcctcata 3100

 gcgacacacc agaaatcaga aaatacaaga aacgattcaa ctcagaaata 3150

 ctttgtgcag ctctgtgggg tgtaaacctt ctggtgggga ctgaaaatgg 3200

 cctgatgctt ttggaccgaa gtgggcaagg caaagtctat aatctgatca 3250

 accggaggcg atttcagcag atggatgtgc tagagggact gaatgtcctt 3300

 gtgacaattt caggaaagaa gaataagcta cgagtttact atctttcatg 3350

 gttaagaaac agaatactac ataatgaccc agaagtagaa aagaaacaag 3400

 gctggatcac tgttggggac ttggaaggct gtatacatta taaagttgtt 3450

 aaatatgaaa ggatcaaatt tttggtgatt gccttaaaga atgctgtgga 3500

 aatatatgct tgggctccta aaccgtatca taaattcatg gcatttaagt 3550

 cttttgcaga tctccagcac aagcctctgc tagttgatct cacggtagaa 3600

 gaaggtcaaa gattaaaggt tatttttggt tcacacactg gtttccatgt 3650

 aattgatgtt gattcaggaa actcttatga tatctacata ccatctcata 3700

 ttcagggcaa tatcactcct catgctattg tcatcttgcc taaaacagat 3750

 ggaatggaaa tgcttgtttg ctatgaggat gagggggtgt atgtaaacac 3800

 ctatggccgg ataactaagg atgtggtgct ccaatgggga gaaatgccca 3850

 cgtctgtggc ctacattcat tccaatcaga taatgggctg gggcgagaaa 3900

 gctattgaga tccggtcagt ggaaacagga catttggatg gagtatttat 3950

 gcataagcga gctcaaaggt taaagtttct atgtgaaaga aatgataagg 4000

 tattttttgc atccgtgcga tctggaggaa gtagccaagt gtttttcatg 4050

 accctcaaca gaaattccat gatgaactgg taa 4083

<210> 2456
<211> 1360
<212> PRT
<213> Homo sapien

<400> 2456
 Met Ala Ser Asp Ser Pro Ala Arg Ser Leu Asp Glu Ile Asp Leu
   1               5                  10                  15

 Ser Ala Leu Arg Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Leu
                  20                  25                  30

 Val Gly Asn Gly Thr Tyr Gly Gln Val Tyr Lys Gly Arg His Val
                  35                  40                  45

 Lys Thr Gly Gln Leu Ala Ala Ile Lys Val Met Asp Val Thr Gly
                  50                  55                  60

 Asp Glu Glu Glu Glu Ile Lys Gln Glu Ile Asn Met Leu Lys Lys
                  65                  70                  75

 Tyr Ser His His Arg Asn Ile Ala Thr Tyr Tyr Gly Ala Phe Ile
                  80                  85                  90

 Lys Lys Asn Pro Pro Gly Met Asp Asp Gln Leu Trp Leu Val Met
                  95                 100                 105

 Glu Phe Cys Gly Ala Gly Ser Val Thr Asp Leu Ile Lys Asn Thr
                 110                 115                 120

 Lys Gly Asn Thr Leu Lys Glu Glu Trp Ile Ala Tyr Ile Cys Arg
                 125                 130                 135

 Glu Ile Leu Arg Gly Leu Ser His Leu His Gln His Lys Val Ile
                 140                 145                 150

 His Arg Asp Ile Lys Gly Gln Asn Val Leu Leu Thr Glu Asn Ala
                 155                 160                 165

 Glu Val Lys Leu Val Asp Phe Gly Val Ser Ala Gln Leu Asp Arg
                 170                 175                 180

 Thr Val Gly Arg Arg Asn Thr Phe Ile Gly Thr Pro Tyr Trp Met
                 185                 190                 195

 Ala Pro Glu Val Ile Ala Cys Asp Glu Asn Pro Asp Ala Thr Tyr
                 200                 205                 210

 Asp Phe Lys Ser Asp Leu Trp Ser Leu Gly Ile Thr Ala Ile Glu
                 215                 220                 225

 Met Ala Glu Gly Ala Pro Pro Leu Cys Asp Met His Pro Met Arg
                 230                 235                 240

 Ala Leu Phe Leu Ile Pro Arg Asn Pro Ala Pro Arg Leu Lys Ser
                 245                 250                 255

 Lys Lys Trp Ser Lys Lys Phe Gln Ser Phe Ile Glu Ser Cys Leu
                 260                 265                 270

 Val Lys Asn His Ser Gln Arg Pro Ala Thr Glu Gln Leu Met Lys
                 275                 280                 285

 His Pro Phe Ile Arg Asp Gln Pro Asn Glu Arg Gln Val Arg Ile
                 290                 295                 300

 Gln Leu Lys Asp His Ile Asp Arg Thr Lys Lys Lys Arg Gly Glu
                 305                 310                 315

 Lys Asp Glu Thr Glu Tyr Glu Tyr Ser Gly Ser Glu Glu Glu Glu
                 320                 325                 330

 Glu Glu Asn Asp Ser Gly Glu Pro Ser Ser Ile Leu Asn Leu Pro
                 335                 340                 345

 Gly Glu Ser Thr Leu Arg Arg Asp Phe Leu Arg Leu Gln Leu Ala
                 350                 355                 360

 Asn Lys Glu Arg Ser Glu Ala Leu Arg Arg Gln Gln Leu Glu Gln
                 365                 370                 375

 Gln Gln Arg Glu Asn Glu Glu His Lys Arg Gln Leu Leu Ala Glu
                 380                 385                 390

 Arg Gln Lys Arg Ile Glu Glu Gln Lys Glu Gln Arg Arg Arg Leu
                 395                 400                 405

 Glu Glu Gln Gln Arg Arg Glu Lys Glu Leu Arg Lys Gln Gln Glu
                 410                 415                 420

 Arg Glu Gln Arg Arg His Tyr Glu Glu Gln Met Arg Arg Glu Glu
                 425                 430                 435

 Glu Arg Arg Arg Ala Glu His Glu Gln Glu Tyr Ile Arg Arg Gln
                 440                 445                 450

 Leu Glu Glu Glu Gln Arg Gln Leu Glu Ile Leu Gln Gln Gln Leu
                 455                 460                 465

 Leu His Glu Gln Ala Leu Leu Leu Glu Tyr Lys Arg Lys Gln Leu
                 470                 475                 480

 Glu Glu Gln Arg Gln Ala Glu Arg Leu Gln Arg Gln Leu Lys Gln
                 485                 490                 495

 Glu Arg Asp Tyr Leu Val Ser Leu Gln His Gln Arg Gln Glu Gln
                 500                 505                 510

 Arg Pro Val Glu Lys Lys Pro Leu Tyr His Tyr Lys Glu Gly Met
                 515                 520                 525

 Ser Pro Ser Glu Lys Pro Ala Trp Ala Lys Glu Val Glu Glu Arg
                 530                 535                 540

 Ser Arg Leu Asn Arg Gln Ser Ser Pro Ala Met Pro His Lys Val
                 545                 550                 555

 Ala Asn Arg Ile Ser Asp Pro Asn Leu Pro Pro Arg Ser Glu Ser
                 560                 565                 570

 Phe Ser Ile Ser Gly Val Gln Pro Ala Arg Thr Pro Pro Met Leu
                 575                 580                 585

 Arg Pro Val Asp Pro Gln Ile Pro His Leu Val Ala Val Lys Ser
                 590                 595                 600

 Gln Gly Pro Ala Leu Thr Ala Ser Gln Ser Val His Glu Gln Pro
                 605                 610                 615

 Thr Lys Gly Leu Ser Gly Phe Gln Glu Ala Leu Asn Val Thr Ser
                 620                 625                 630

 His Arg Val Glu Met Pro Arg Gln Asn Ser Asp Pro Thr Ser Glu
                 635                 640                 645

 Asn Pro Pro Leu Pro Thr Arg Ile Glu Lys Phe Asp Arg Ser Ser
                 650                 655                 660

 Trp Leu Arg Gln Glu Glu Asp Ile Pro Pro Lys Val Pro Gln Arg
                 665                 670                 675

 Thr Thr Ser Ile Ser Pro Ala Leu Ala Arg Lys Asn Ser Pro Gly
                 680                 685                 690

 Asn Gly Ser Ala Leu Gly Pro Arg Leu Gly Ser Gln Pro Ile Arg
                 695                 700                 705

 Ala Ser Asn Pro Asp Leu Arg Arg Thr Glu Pro Ile Leu Glu Ser
                 710                 715                 720

 Pro Leu Gln Arg Thr Ser Ser Gly Ser Ser Ser Ser Ser Ser Thr
                 725                 730                 735

 Pro Ser Ser Gln Pro Ser Ser Gln Gly Gly Ser Gln Pro Gly Ser
                 740                 745                 750

 Gln Ala Gly Ser Ser Glu Arg Thr Arg Val Arg Ala Asn Ser Lys
                 755                 760                 765

 Ser Glu Gly Ser Pro Val Leu Pro His Glu Pro Ala Lys Val Lys
                 770                 775                 780

 Pro Glu Glu Ser Arg Asp Ile Thr Arg Pro Ser Arg Pro Ala Ser
                 785                 790                 795

 Tyr Lys Lys Ala Ile Asp Glu Asp Leu Thr Ala Leu Ala Lys Glu
                 800                 805                 810

 Leu Arg Glu Leu Arg Ile Glu Glu Thr Asn Arg Pro Met Lys Lys
                 815                 820                 825

 Val Thr Asp Tyr Ser Ser Ser Ser Glu Glu Ser Glu Ser Ser Glu
                 830                 835                 840

 Glu Glu Glu Glu Asp Gly Glu Ser Glu Thr His Asp Gly Thr Val
                 845                 850                 855

 Ala Val Ser Asp Ile Pro Arg Leu Ile Pro Thr Gly Ala Pro Gly
                 860                 865                 870

 Ser Asn Glu Gln Tyr Asn Val Gly Met Val Gly Thr His Gly Leu
                 875                 880                 885

 Glu Thr Ser His Ala Asp Ser Phe Ser Gly Ser Ile Ser Arg Glu
                 890                 895                 900

 Gly Thr Leu Met Ile Arg Glu Thr Ser Gly Glu Lys Lys Arg Ser
                 905                 910                 915

 Gly His Ser Asp Ser Asn Gly Phe Ala Gly His Ile Asn Leu Pro
                 920                 925                 930

 Asp Leu Val Gln Gln Ser His Ser Pro Ala Gly Thr Pro Thr Glu
                 935                 940                 945

 Gly Leu Gly Arg Val Ser Thr His Ser Gln Glu Met Asp Ser Gly
                 950                 955                 960

 Thr Glu Tyr Gly Met Gly Ser Ser Thr Lys Ala Ser Phe Thr Pro
                 965                 970                 975

 Phe Val Asp Pro Arg Val Tyr Gln Thr Ser Pro Thr Asp Glu Asp
                 980                 985                 990

 Glu Glu Asp Glu Glu Ser Ser Ala Ala Ala Leu Phe Thr Ser Glu
                 995                1000                1005

 Leu Leu Arg Gln Glu Gln Ala Lys Leu Asn Glu Ala Arg Lys Ile
                1010                1015                1020

 Ser Val Val Asn Val Asn Pro Thr Asn Ile Arg Pro His Ser Asp
                1025                1030                1035

 Thr Pro Glu Ile Arg Lys Tyr Lys Lys Arg Phe Asn Ser Glu Ile
                1040                1045                1050

 Leu Cys Ala Ala Leu Trp Gly Val Asn Leu Leu Val Gly Thr Glu
                1055                1060                1065

 Asn Gly Leu Met Leu Leu Asp Arg Ser Gly Gln Gly Lys Val Tyr
                1070                1075                1080

 Asn Leu Ile Asn Arg Arg Arg Phe Gln Gln Met Asp Val Leu Glu
                1085                1090                1095

 Gly Leu Asn Val Leu Val Thr Ile Ser Gly Lys Lys Asn Lys Leu
                1100                1105                1110

 Arg Val Tyr Tyr Leu Ser Trp Leu Arg Asn Arg Ile Leu His Asn
                1115                1120                1125

 Asp Pro Glu Val Glu Lys Lys Gln Gly Trp Ile Thr Val Gly Asp
                1130                1135                1140

 Leu Glu Gly Cys Ile His Tyr Lys Val Val Lys Tyr Glu Arg Ile
                1145                1150                1155

 Lys Phe Leu Val Ile Ala Leu Lys Asn Ala Val Glu Ile Tyr Ala
                1160                1165                1170

 Trp Ala Pro Lys Pro Tyr His Lys Phe Met Ala Phe Lys Ser Phe
                1175                1180                1185

 Ala Asp Leu Gln His Lys Pro Leu Leu Val Asp Leu Thr Val Glu
                1190                1195                1200

 Glu Gly Gln Arg Leu Lys Val Ile Phe Gly Ser His Thr Gly Phe
                1205                1210                1215

 His Val Ile Asp Val Asp Ser Gly Asn Ser Tyr Asp Ile Tyr Ile
                1220                1225                1230

 Pro Ser His Ile Gln Gly Asn Ile Thr Pro His Ala Ile Val Ile
                1235                1240                1245

 Leu Pro Lys Thr Asp Gly Met Glu Met Leu Val Cys Tyr Glu Asp
                1250                1255                1260

 Glu Gly Val Tyr Val Asn Thr Tyr Gly Arg Ile Thr Lys Asp Val
                1265                1270                1275

 Val Leu Gln Trp Gly Glu Met Pro Thr Ser Val Ala Tyr Ile His
                1280                1285                1290

 Ser Asn Gln Ile Met Gly Trp Gly Glu Lys Ala Ile Glu Ile Arg
                1295                1300                1305

 Ser Val Glu Thr Gly His Leu Asp Gly Val Phe Met His Lys Arg
                1310                1315                1320

 Ala Gln Arg Leu Lys Phe Leu Cys Glu Arg Asn Asp Lys Val Phe
                1325                1330                1335

 Phe Ala Ser Val Arg Ser Gly Gly Ser Ser Gln Val Phe Phe Met
                1340                1345                1350

 Thr Leu Asn Arg Asn Ser Met Met Asn Trp
                1355                1360

<210> 2457
<211> 724
<212> DNA
<213> Homo sapien

<400> 2457
 gctgcggccg cccgcgcgga cccggcgaga ggcggcggcg ggagcggcgg 50

 tgatggacgg gtccggggag cagcccagag gcggggggcc caccagctct 100

 gagcagatca tgaagacagg ggcccttttg cttcagggga tgattgccgc 150

 cgtggacaca gactcccccc gagaggtctt tttccgagtg gcagctgaca 200

 tgttttctga cggcaacttc aactggggcc gggttgtcgc ccttttctac 250

 tttgccagca aactggtgct caaggccctg tgcaccaagg tgccggaact 300

 gatcagaacc atcatgggct ggacattgga cttcctccgg gagcggctgt 350

 tgggctggat ccaagaccag ggtggttggg acggcctcct ctcctacttt 400

 gggacgccca cgtggcagac cgtgaccatc tttgtggcgg gagtgctcac 450

 cgcctcgctc accatctgga agaagatggg ctgaggcccc cagctgcctt 500

 ggactgtgtt tttcctccat aaattatggc atttttctgg gaggggtggg 550

 gattggggga catgggcatt tttcttactt ttgtaattat tggggggtgt 600

 ggggaagagt ggtcttgagg gggtaataaa cctccttcgg gacacaaaaa 650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 700

 aaaaaaaaaa aaaaaaaaaa aaaa 724

<210> 2458
<211> 143
<212> PRT
<213> Homo sapien

<400> 2458
 Met Asp Gly Ser Gly Glu Gln Pro Arg Gly Gly Gly Pro Thr Ser
   1               5                  10                  15

 Ser Glu Gln Ile Met Lys Thr Gly Ala Leu Leu Leu Gln Gly Met
                  20                  25                  30

 Ile Ala Ala Val Asp Thr Asp Ser Pro Arg Glu Val Phe Phe Arg
                  35                  40                  45

 Val Ala Ala Asp Met Phe Ser Asp Gly Asn Phe Asn Trp Gly Arg
                  50                  55                  60

 Val Val Ala Leu Phe Tyr Phe Ala Ser Lys Leu Val Leu Lys Ala
                  65                  70                  75

 Leu Cys Thr Lys Val Pro Glu Leu Ile Arg Thr Ile Met Gly Trp
                  80                  85                  90

 Thr Leu Asp Phe Leu Arg Glu Arg Leu Leu Gly Trp Ile Gln Asp
                  95                 100                 105

 Gln Gly Gly Trp Asp Gly Leu Leu Ser Tyr Phe Gly Thr Pro Thr
                 110                 115                 120

 Trp Gln Thr Val Thr Ile Phe Val Ala Gly Val Leu Thr Ala Ser
                 125                 130                 135

 Leu Thr Ile Trp Lys Lys Met Gly
                 140

<210> 2459
<211> 2545
<212> DNA
<213> Homo sapien

<400> 2459
 gagggctggc cagtgaggct cggcccgggg aaagtgaaag tttgcctggg 50

 tcctctcggc gccagagccg ctctccgcat cccaggacag cggtgcggcc 100

 ctcggccggg gcgcccactc cgcagcagcc agcgagcgag cgagcgagcg 150

 agggcggccg acgcgcccgg ccgggaccca gctgcccgta tgaccgcgcc 200

 gggcgccgcc gggcgctgcc ctcccacgac atggctgggc tccctgctgt 250

 tgttggtctg tctcctggcg agcaggagta tcaccgagga ggtgtcggag 300

 tactgtagcc acatgattgg gagtggacac ctgcagtctc tgcagcggct 350

 gattgacagt cagatggaga cctcgtgcca aattacattt gagtttgtag 400

 accaggaaca gttgaaagat ccagtgtgct accttaagaa ggcatttctc 450

 ctggtacaag acataatgga ggacaccatg cgcttcagag ataacacccc 500

 caatgccatc gccattgtgc agctgcagga actctctttg aggctgaaga 550

 gctgcttcac caaggattat gaagagcatg acaaggcctg cgtccgaact 600

 ttctatgaga cacctctcca gttgctggag aaggtcaaga atgtctttaa 650

 tgaaacaaag aatctccttg acaaggactg gaatattttc agcaagaact 700

 gcaacaacag ctttgctgaa tgctccagcc aagatgtggt gaccaagcct 750

 gattgcaact gcctgtaccc caaagccatc cctagcagtg acccggcctc 800

 tgtctcccct catcagcccc tcgccccctc catggcccct gtggctggct 850

 tgacctggga ggactctgag ggaactgagg gcagctccct cttgcctggt 900

 gagcagcccc tgcacacagt ggatccaggc agtgccaagc agcggccacc 950

 caggagcacc tgccagagct ttgagccgcc agagacccca gttgtcaagg 1000

 acagcaccat cggtggctca ccacagcctc gcccctctgt cggggccttc 1050

 aaccccggga tggaggatat tcttgactct gcaatgggca ctaattgggt 1100

 cccagaagaa gcctctggag aggccagtga gattcccgta ccccaaggga 1150

 cagagctttc cccctccagg ccaggagggg gcagcatgca gacagagccc 1200

 gccagaccca gcaacttcct ctcagcatct tctccactcc ctgcatcagc 1250

 aaagggccaa cagccggcag atgtaactgg tacagccttg cccagggtgg 1300

 gccccgtgag gcccactggc caggactgga atcacacccc ccagaagaca 1350

 gaccatccat ctgccctgct cagagacccc ccggagccag gctctcccag 1400

 gatctcatca ctgcgccccc agggcctcag caacccctcc accctctctg 1450

 ctcagccaca gctttccaga agccactcct cgggcagcgt gctgcccctt 1500

 ggggagctgg agggcaggag gagcaccagg gatcggagga gccccgcaga 1550

 gccagaagga ggaccagcaa gtgaaggggc agccaggccc ctgccccgtt 1600

 ttaactccgt tcctttgact gacacaggcc atgagaggca gtccgaggga 1650

 tcctccagcc cgcagctcca ggagtctgtc ttccacctgc tggtgcccag 1700

 tgtcatcctg gtcttgctgg ccgtcggagg cctcttgttc tacaggtgga 1750

 ggcggcggag ccatcaagag cctcagagag cggattctcc cttggagcaa 1800

 ccagagggca gccccctgac tcaggatgac agacaggtgg aactgccagt 1850

 gtagagggaa ttctaagacc cctcaccatc ctggacacac tcgtttgtca 1900

 atgtccctct gaaaatgtga cgcccagccc cggacacagt actccagatg 1950

 ttgtctgacc agctcagaga gagtacagtg ggactgttac cttccttgat 2000

 atggacagta ttcttctatt tgtgcagatt aagattgcat tagttttttt 2050

 cttaacaact gcatcatact gttgtcatat gttgagcctg tggttctata 2100

 aaacccctag ttccatttcc cataaacttc tgtcaagcca gaccatctct 2150

 accctgtact tggacaactt aactttttta accaaagtgc agtttatgtt 2200

 cacctttgtt aaagccacct ttgtggtttc tgcccatcac ctgaacctac 2250

 tgaagttgtg tgaaatccta attctgtcat ctccgtagcc ctcccagttg 2300

 tgcctcctgc acattgatga gtgcctgctg ttgtctttgc ccatgttgtt 2350

 gatgtagctg tgaccctatt gttcctcacc cctgcccccc gccaacccca 2400

 gctggcccac ctcttccccc tcccacccaa gcccacagcc agcccatcag 2450

 gaagccttcc tggcttctcc acaaccttct gactgtcttt tcagtcatgc 2500

 cccctgctct tttgtatttg gctaatagta tatcaatttg cactt 2545

<210> 2460
<211> 554
<212> PRT
<213> Homo sapien

<400> 2460
 Met Thr Ala Pro Gly Ala Ala Gly Arg Cys Pro Pro Thr Thr Trp
   1               5                  10                  15

 Leu Gly Ser Leu Leu Leu Leu Val Cys Leu Leu Ala Ser Arg Ser
                  20                  25                  30

 Ile Thr Glu Glu Val Ser Glu Tyr Cys Ser His Met Ile Gly Ser
                  35                  40                  45

 Gly His Leu Gln Ser Leu Gln Arg Leu Ile Asp Ser Gln Met Glu
                  50                  55                  60

 Thr Ser Cys Gln Ile Thr Phe Glu Phe Val Asp Gln Glu Gln Leu
                  65                  70                  75

 Lys Asp Pro Val Cys Tyr Leu Lys Lys Ala Phe Leu Leu Val Gln
                  80                  85                  90

 Asp Ile Met Glu Asp Thr Met Arg Phe Arg Asp Asn Thr Pro Asn
                  95                 100                 105

 Ala Ile Ala Ile Val Gln Leu Gln Glu Leu Ser Leu Arg Leu Lys
                 110                 115                 120

 Ser Cys Phe Thr Lys Asp Tyr Glu Glu His Asp Lys Ala Cys Val
                 125                 130                 135

 Arg Thr Phe Tyr Glu Thr Pro Leu Gln Leu Leu Glu Lys Val Lys
                 140                 145                 150

 Asn Val Phe Asn Glu Thr Lys Asn Leu Leu Asp Lys Asp Trp Asn
                 155                 160                 165

 Ile Phe Ser Lys Asn Cys Asn Asn Ser Phe Ala Glu Cys Ser Ser
                 170                 175                 180

 Gln Asp Val Val Thr Lys Pro Asp Cys Asn Cys Leu Tyr Pro Lys
                 185                 190                 195

 Ala Ile Pro Ser Ser Asp Pro Ala Ser Val Ser Pro His Gln Pro
                 200                 205                 210

 Leu Ala Pro Ser Met Ala Pro Val Ala Gly Leu Thr Trp Glu Asp
                 215                 220                 225

 Ser Glu Gly Thr Glu Gly Ser Ser Leu Leu Pro Gly Glu Gln Pro
                 230                 235                 240

 Leu His Thr Val Asp Pro Gly Ser Ala Lys Gln Arg Pro Pro Arg
                 245                 250                 255

 Ser Thr Cys Gln Ser Phe Glu Pro Pro Glu Thr Pro Val Val Lys
                 260                 265                 270

 Asp Ser Thr Ile Gly Gly Ser Pro Gln Pro Arg Pro Ser Val Gly
                 275                 280                 285

 Ala Phe Asn Pro Gly Met Glu Asp Ile Leu Asp Ser Ala Met Gly
                 290                 295                 300

 Thr Asn Trp Val Pro Glu Glu Ala Ser Gly Glu Ala Ser Glu Ile
                 305                 310                 315

 Pro Val Pro Gln Gly Thr Glu Leu Ser Pro Ser Arg Pro Gly Gly
                 320                 325                 330

 Gly Ser Met Gln Thr Glu Pro Ala Arg Pro Ser Asn Phe Leu Ser
                 335                 340                 345

 Ala Ser Ser Pro Leu Pro Ala Ser Ala Lys Gly Gln Gln Pro Ala
                 350                 355                 360

 Asp Val Thr Gly Thr Ala Leu Pro Arg Val Gly Pro Val Arg Pro
                 365                 370                 375

 Thr Gly Gln Asp Trp Asn His Thr Pro Gln Lys Thr Asp His Pro
                 380                 385                 390

 Ser Ala Leu Leu Arg Asp Pro Pro Glu Pro Gly Ser Pro Arg Ile
                 395                 400                 405

 Ser Ser Leu Arg Pro Gln Gly Leu Ser Asn Pro Ser Thr Leu Ser
                 410                 415                 420

 Ala Gln Pro Gln Leu Ser Arg Ser His Ser Ser Gly Ser Val Leu
                 425                 430                 435

 Pro Leu Gly Glu Leu Glu Gly Arg Arg Ser Thr Arg Asp Arg Arg
                 440                 445                 450

 Ser Pro Ala Glu Pro Glu Gly Gly Pro Ala Ser Glu Gly Ala Ala
                 455                 460                 465

 Arg Pro Leu Pro Arg Phe Asn Ser Val Pro Leu Thr Asp Thr Gly
                 470                 475                 480

 His Glu Arg Gln Ser Glu Gly Ser Ser Ser Pro Gln Leu Gln Glu
                 485                 490                 495

 Ser Val Phe His Leu Leu Val Pro Ser Val Ile Leu Val Leu Leu
                 500                 505                 510

 Ala Val Gly Gly Leu Leu Phe Tyr Arg Trp Arg Arg Arg Ser His
                 515                 520                 525

 Gln Glu Pro Gln Arg Ala Asp Ser Pro Leu Glu Gln Pro Glu Gly
                 530                 535                 540

 Ser Pro Leu Thr Gln Asp Asp Arg Gln Val Glu Leu Pro Val
                 545                 550

<210> 2461
<211> 3804
<212> DNA
<213> Homo sapien

<400> 2461
 taaagtcatc aaaacaacgt tatatcctgt gtgaaatgct gcagtcagga 50

 tgccttgtgg tttgagtgcc ttgatcatgt gccctaaggg gatggtggcg 100

 gtggtggtgg ccgtggatga cggagactct caggccttgg caggtgcgtc 150

 tttcagttcc cctcacactt cgggttcctc ggggaggagg ggctggaacc 200

 ctagcccatc gtcaggacaa agatgctcag gctgctcttg gctctcaact 250

 tattcccttc aattcaagta acaggaaaca agattttggt gaagcagtcg 300

 cccatgcttg tagcgtacga caatgcggtc aaccttagct gcaagtattc 350

 ctacaatctc ttctcaaggg agttccgggc atcccttcac aaaggactgg 400

 atagtgctgt ggaagtctgt gttgtatatg ggaattactc ccagcagctt 450

 caggtttact caaaaacggg gttcaactgt gatgggaaat tgggcaatga 500

 atcagtgaca ttctacctcc agaatttgta tgttaaccaa acagatattt 550

 acttctgcaa aattgaagtt atgtatcctc ctccttacct agacaatgag 600

 aagagcaatg gaaccattat ccatgtgaaa gggaaacacc tttgtccaag 650

 tcccctattt cccggacctt ctaagccctt ttgggtgctg gtggtggttg 700

 gtggagtcct ggcttgctat agcttgctag taacagtggc ctttattatt 750

 ttctgggtga ggagtaagag gagcaggctc ctgcacagtg actacatgaa 800

 catgactccc cgccgccccg ggcccacccg caagcattac cagccctatg 850

 ccccaccacg cgacttcgca gcctatcgct cctgacacgg acgcctatcc 900

 agaagccagc cggctggcag cccccatctg ctcaatatca ctgctctgga 950

 taggaaatga ccgccatctc cagccggcca cctcaggccc ctgttgggcc 1000

 accaatgcca atttttctcg agtgactaga ccaaatatca agatcatttt 1050

 gagactctga aatgaagtaa aagagatttc ctgtgacagg ccaagtctta 1100

 cagtgccatg gcccacattc caacttacca tgtacttagt gacttgactg 1150

 agaagttagg gtagaaaaca aaaagggagt ggattctggg agcctcttcc 1200

 ctttctcact cacctgcaca tctcagtcaa gcaaagtgtg gtatccacag 1250

 acattttagt tgcagaagaa aggctaggaa atcattcctt ttggttaaat 1300

 gggtgtttaa tcttttggtt agtgggttaa acggggtaag ttagagtagg 1350

 gggagggata ggaagacata tttaaaaacc attaaaacac tgtctcccac 1400

 tcatgaaatg agccacgtag ttcctattta atgctgtttt cctttagttt 1450

 agaaatacat agacattgtc ttttatgaat tctgatcata tttagtcatt 1500

 ttgaccaaat gagggatttg gtcaaatgag ggattccctc aaagcaatat 1550

 caggtaaacc aagttgcttt cctcactccc tgtcatgaga cttcagtgtt 1600

 aatgttcaca atatactttc gaaagaataa aatagttctc ctacatgaag 1650

 aaagaatatg tcaggaaata aggtcacttt atgtcaaaat tatttgagta 1700

 ctatgggacc tggcgcagtg gctcatgctt gtaatcccag cactttggga 1750

 ggccgaggtg ggcagatcac ttgagatcag gaccagcctg gtcaagatgg 1800

 tgaaactccg tctgtactaa aaatacaaaa tttagcttgg cctggtggca 1850

 ggcacctgta atcccagctg cccaggaggc tgaggcatga gaatcgcttg 1900

 aacctggcag gcggaggttg cagtgagccg agatagtgcc acagctctcc 1950

 agcctgggcg acagagtgag actccatctc aaacaacaac aacaacaaca 2000

 acaacaacaa caaaccacaa aattatttga gtactgtgaa ggattatttg 2050

 tctaacagtt cattccaatc agaccaggta ggagctttcc tgtttcatat 2100

 gtttcagggt tgcacagttg gtctctttaa tgtcggtgtg gagatccaaa 2150

 gtgggttgtg gaaagagcgt ccataggaga agtgagaata ctgtgaaaag 2200

 ggatgttagc attcattaga gtatgaggat gagtcccaag aaggttcttt 2250

 ggaaggagga cgaatagaat ggagtaatga aattcttgcc atgtgctgag 2300

 gagatagcca gcattaggtg acaatcttcc agaagtggtc aggcagaagg 2350

 tgccctggtg agagctcctt tacagggact ttatgtggtt tagggctcag 2400

 agctccaaaa ctctgggctc agctgctcct gtaccttgga ggtccattca 2450

 catgggaaag tattttggaa tgtgtctttt gaagagagca tcagagttct 2500

 taagggactg ggtaaggcct gaccctgaaa tgaccatgga tatttttcta 2550

 cctacagttt gagtcaacta gaatatgcct ggggaccttg aagaatgccc 2600

 ttcagtggcc ctcaccattt gttcatgctt cagttaattc aggtgttgaa 2650

 ggagcttagg ttttagaggc acgtagactt ggttcaagtc tcgttagtag 2700

 ttgaatagcc tcaggcaagt cactgcccac ctaagatgat ggttcttcaa 2750

 ctataaatgg agataatggt tacaaatgtc tcttcctata gtataatctc 2800

 cataagggca tggcccaagt ctgtctttga ctctgcctat ccctgacgtt 2850

 tagtagcatg cccgacatac aatgttagct attggtatta ttgccatata 2900

 gataaattat gtataaaaat taaactgggc aatagcctaa gaagggggga 2950

 atattgtaac acaaatttaa acccactacg cagggatgag gtgctataat 3000

 atgaggacct tttaacttcc atcattttcc tgtttcttga aatagtttat 3050

 cttgtaatga aatataaggc acctcccact tttatgtata gaaagaggtc 3100

 ttttaatttt tttttaatgt gagaaggaag ggaggagtag gaatcttgag 3150

 attccatatc gaaaatactg tactttggtt gatttttaag tgggcttcca 3200

 ttccatggat ttaatcagtc ccaagaagat caaactcagc agtacttggg 3250

 tgctgaagaa ctgttggatt taccctggca cgtgtgccac ttgcccagct 3300

 tcttgggcac acagagttct tcaatccaag ttatcagatt gtatttgaaa 3350

 atgacagagc tggagagttt tttgaaatgg cagtggcaaa taaataaata 3400

 ctttttttta aatggaaaga cttgatctat ggtaataaat gattttgttt 3450

 tctgactgga aaaataggcc tactaaagat gaatcacact tgagatgttt 3500

 cttactcact ctgcacagaa acaaagaaga aatgttatac agggaagtcc 3550

 gttttcacta ttagtatgaa ccaagaaatg gttcaaaaac agtggtagga 3600

 gcaatgcttt catagtttca gatatggtag ttatgaagaa aacaatgtca 3650

 tttgctgcta ttattgtaag agtcttataa ttaatggtac tcctataatt 3700

 tttgattgtg agctcaccta tttgggttaa gcatgccaat ttaaagagac 3750

 caagtgtatg tacattatgt tctacatatt cagtgataaa attactaaac 3800

 tact 3804

<210> 2462
<211> 220
<212> PRT
<213> Homo sapien

<400> 2462
 Met Leu Arg Leu Leu Leu Ala Leu Asn Leu Phe Pro Ser Ile Gln
   1               5                  10                  15

 Val Thr Gly Asn Lys Ile Leu Val Lys Gln Ser Pro Met Leu Val
                  20                  25                  30

 Ala Tyr Asp Asn Ala Val Asn Leu Ser Cys Lys Tyr Ser Tyr Asn
                  35                  40                  45

 Leu Phe Ser Arg Glu Phe Arg Ala Ser Leu His Lys Gly Leu Asp
                  50                  55                  60

 Ser Ala Val Glu Val Cys Val Val Tyr Gly Asn Tyr Ser Gln Gln
                  65                  70                  75

 Leu Gln Val Tyr Ser Lys Thr Gly Phe Asn Cys Asp Gly Lys Leu
                  80                  85                  90

 Gly Asn Glu Ser Val Thr Phe Tyr Leu Gln Asn Leu Tyr Val Asn
                  95                 100                 105

 Gln Thr Asp Ile Tyr Phe Cys Lys Ile Glu Val Met Tyr Pro Pro
                 110                 115                 120

 Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val
                 125                 130                 135

 Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser
                 140                 145                 150

 Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys
                 155                 160                 165

 Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg
                 170                 175                 180

 Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr
                 185                 190                 195

 Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala
                 200                 205                 210

 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser
                 215                 220

<210> 2463
<211> 3804
<212> DNA
<213> Homo sapien

<400> 2463
 taaagtcatc aaaacaacgt tatatcctgt gtgaaatgct gcagtcagga 50

 tgccttgtgg tttgagtgcc ttgatcatgt gccctaaggg gatggtggcg 100

 gtggtggtgg ccgtggatga cggagactct caggccttgg caggtgcgtc 150

 tttcagttcc cctcacactt cgggttcctc ggggaggagg ggctggaacc 200

 ctagcccatc gtcaggacaa agatgctcag gctgctcttg gctctcaact 250

 tattcccttc aattcaagta acaggaaaca agattttggt gaagcagtcg 300

 cccatgcttg tagcgtacga caatgcggtc aaccttagct gcaagtattc 350

 ctacaatctc ttctcaaggg agttccgggc atcccttcac aaaggactgg 400

 atagtgctgt ggaagtctgt gttgtatatg ggaattactc ccagcagctt 450

 caggtttact caaaaacggg gttcaactgt gatgggaaat tgggcaatga 500

 atcagtgaca ttctacctcc agaatttgta tgttaaccaa acagatattt 550

 acttctgcaa aattgaagtt atgtatcctc ctccttacct agacaatgag 600

 aagagcaatg gaaccattat ccatgtgaaa gggaaacacc tttgtccaag 650

 tcccctattt cccggacctt ctaagccctt ttgggtgctg gtggtggttg 700

 gtggagtcct ggcttgctat agcttgctag taacagtggc ctttattatt 750

 ttctgggtga ggagtaagag gagcaggctc ctgcacagtg actacatgaa 800

 catgactccc cgccgccccg ggcccacccg caagcattac cagccctatg 850

 ccccaccacg cgacttcgca gcctatcgct cctgacacgg acgcctatcc 900

 agaagccagc cggctggcag cccccatctg ctcaatatca ctgctctgga 950

 taggaaatga ccgccatctc cagccggcca cctcaggccc ctgttgggcc 1000

 accaatgcca atttttctcg agtgactaga ccaaatatca agatcatttt 1050

 gagactctga aatgaagtaa aagagatttc ctgtgacagg ccaagtctta 1100

 cagtgccatg gcccacattc caacttacca tgtacttagt gacttgactg 1150

 agaagttagg gtagaaaaca aaaagggagt ggattctggg agcctcttcc 1200

 ctttctcact cacctgcaca tctcagtcaa gcaaagtgtg gtatccacag 1250

 acattttagt tgcagaagaa aggctaggaa atcattcctt ttggttaaat 1300

 gggtgtttaa tcttttggtt agtgggttaa acggggtaag ttagagtagg 1350

 gggagggata ggaagacata tttaaaaacc attaaaacac tgtctcccac 1400

 tcatgaaatg agccacgtag ttcctattta atgctgtttt cctttagttt 1450

 agaaatacat agacattgtc ttttatgaat tctgatcata tttagtcatt 1500

 ttgaccaaat gagggatttg gtcaaatgag ggattccctc aaagcaatat 1550

 caggtaaacc aagttgcttt cctcactccc tgtcatgaga cttcagtgtt 1600

 aatgttcaca atatactttc gaaagaataa aatagttctc ctacatgaag 1650

 aaagaatatg tcaggaaata aggtcacttt atgtcaaaat tatttgagta 1700

 ctatgggacc tggcgcagtg gctcatgctt gtaatcccag cactttggga 1750

 ggccgaggtg ggcagatcac ttgagatcag gaccagcctg gtcaagatgg 1800

 tgaaactccg tctgtactaa aaatacaaaa tttagcttgg cctggtggca 1850

 ggcacctgta atcccagctg cccaggaggc tgaggcatga gaatcgcttg 1900

 aacctggcag gcggaggttg cagtgagccg agatagtgcc acagctctcc 1950

 agcctgggcg acagagtgag actccatctc aaacaacaac aacaacaaca 2000

 acaacaacaa caaaccacaa aattatttga gtactgtgaa ggattatttg 2050

 tctaacagtt cattccaatc agaccaggta ggagctttcc tgtttcatat 2100

 gtttcagggt tgcacagttg gtctctttaa tgtcggtgtg gagatccaaa 2150

 gtgggttgtg gaaagagcgt ccataggaga agtgagaata ctgtgaaaag 2200

 ggatgttagc attcattaga gtatgaggat gagtcccaag aaggttcttt 2250

 ggaaggagga cgaatagaat ggagtaatga aattcttgcc atgtgctgag 2300

 gagatagcca gcattaggtg acaatcttcc agaagtggtc aggcagaagg 2350

 tgccctggtg agagctcctt tacagggact ttatgtggtt tagggctcag 2400

 agctccaaaa ctctgggctc agctgctcct gtaccttgga ggtccattca 2450

 catgggaaag tattttggaa tgtgtctttt gaagagagca tcagagttct 2500

 taagggactg ggtaaggcct gaccctgaaa tgaccatgga tatttttcta 2550

 cctacagttt gagtcaacta gaatatgcct ggggaccttg aagaatgccc 2600

 ttcagtggcc ctcaccattt gttcatgctt cagttaattc aggtgttgaa 2650

 ggagcttagg ttttagaggc acgtagactt ggttcaagtc tcgttagtag 2700

 ttgaatagcc tcaggcaagt cactgcccac ctaagatgat ggttcttcaa 2750

 ctataaatgg agataatggt tacaaatgtc tcttcctata gtataatctc 2800

 cataagggca tggcccaagt ctgtctttga ctctgcctat ccctgacgtt 2850

 tagtagcatg cccgacatac aatgttagct attggtatta ttgccatata 2900

 gataaattat gtataaaaat taaactgggc aatagcctaa gaagggggga 2950

 atattgtaac acaaatttaa acccactacg cagggatgag gtgctataat 3000

 atgaggacct tttaacttcc atcattttcc tgtttcttga aatagtttat 3050

 cttgtaatga aatataaggc acctcccact tttatgtata gaaagaggtc 3100

 ttttaatttt tttttaatgt gagaaggaag ggaggagtag gaatcttgag 3150

 attccatatc gaaaatactg tactttggtt gatttttaag tgggcttcca 3200

 ttccatggat ttaatcagtc ccaagaagat caaactcagc agtacttggg 3250

 tgctgaagaa ctgttggatt taccctggca cgtgtgccac ttgcccagct 3300

 tcttgggcac acagagttct tcaatccaag ttatcagatt gtatttgaaa 3350

 atgacagagc tggagagttt tttgaaatgg cagtggcaaa taaataaata 3400

 ctttttttta aatggaaaga cttgatctat ggtaataaat gattttgttt 3450

 tctgactgga aaaataggcc tactaaagat gaatcacact tgagatgttt 3500

 cttactcact ctgcacagaa acaaagaaga aatgttatac agggaagtcc 3550

 gttttcacta ttagtatgaa ccaagaaatg gttcaaaaac agtggtagga 3600

 gcaatgcttt catagtttca gatatggtag ttatgaagaa aacaatgtca 3650

 tttgctgcta ttattgtaag agtcttataa ttaatggtac tcctataatt 3700

 tttgattgtg agctcaccta tttgggttaa gcatgccaat ttaaagagac 3750

 caagtgtatg tacattatgt tctacatatt cagtgataaa attactaaac 3800

 tact 3804

<210> 2464
<211> 220
<212> PRT
<213> Homo sapien

<400> 2464
 Met Leu Arg Leu Leu Leu Ala Leu Asn Leu Phe Pro Ser Ile Gln
   1               5                  10                  15

 Val Thr Gly Asn Lys Ile Leu Val Lys Gln Ser Pro Met Leu Val
                  20                  25                  30

 Ala Tyr Asp Asn Ala Val Asn Leu Ser Cys Lys Tyr Ser Tyr Asn
                  35                  40                  45

 Leu Phe Ser Arg Glu Phe Arg Ala Ser Leu His Lys Gly Leu Asp
                  50                  55                  60

 Ser Ala Val Glu Val Cys Val Val Tyr Gly Asn Tyr Ser Gln Gln
                  65                  70                  75

 Leu Gln Val Tyr Ser Lys Thr Gly Phe Asn Cys Asp Gly Lys Leu
                  80                  85                  90

 Gly Asn Glu Ser Val Thr Phe Tyr Leu Gln Asn Leu Tyr Val Asn
                  95                 100                 105

 Gln Thr Asp Ile Tyr Phe Cys Lys Ile Glu Val Met Tyr Pro Pro
                 110                 115                 120

 Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly Thr Ile Ile His Val
                 125                 130                 135

 Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe Pro Gly Pro Ser
                 140                 145                 150

 Lys Pro Phe Trp Val Leu Val Val Val Gly Gly Val Leu Ala Cys
                 155                 160                 165

 Tyr Ser Leu Leu Val Thr Val Ala Phe Ile Ile Phe Trp Val Arg
                 170                 175                 180

 Ser Lys Arg Ser Arg Leu Leu His Ser Asp Tyr Met Asn Met Thr
                 185                 190                 195

 Pro Arg Arg Pro Gly Pro Thr Arg Lys His Tyr Gln Pro Tyr Ala
                 200                 205                 210

 Pro Pro Arg Asp Phe Ala Ala Tyr Arg Ser
                 215                 220

<210> 2465
<211> 2010
<212> DNA
<213> Homo sapien

<400> 2465
 atgtggctct tcttcgggat cactggattg ctgacggcag ccctctcagg 50

 tcatccatct ccagccccac ctgaccagct caacaccagc agtgcagaga 100

 gtgagctctg ggagccaggg gagcggcttc cggtccgtct gacaaacggg 150

 agcagcagct gcagcgggac ggtggaggtg cggctcgagg cgtcctggga 200

 gcccgcgtgc ggggcgctct gggacagccg cgccgccgag gccgtgtgcc 250

 gagcactggg ctgcggcggg gcggaggccg cctctcagct cgccccgccg 300

 acccctgagc tgccgccccc gcctgcagcc gggaacacca gcgtagcagc 350

 taatgccact ctggccgggg cgcccgccct cctgtgcagc ggcgccgagt 400

 ggcggctctg cgaggtggtg gagcacgcgt gccgcagcga cgggaggcgg 450

 gcccgtgtca cctgtgcaga gaaccgcgcg ctgcgcctgg tggacggtgg 500

 cggcgcctgc gccggccgcg tggagatgct ggagcatggc gagtggggat 550

 cagtgtgcga tgacacttgg gacctggagg acgcccacgt ggtgtgcagg 600

 caactgggct gcggctgggc agtccaggcc ctgcccggct tgcacttcac 650

 gcccggccgc gggcctatcc accgggacca ggtgaactgc tcgggggccg 700

 aagcttacct gtgggactgc ccggggctgc caggacagca ctactgcggc 750

 cacaaagagg acgcgggcgt ggtgtgctca gagcaccagt cctggcgcct 800

 gacagggggc gctgaccgct gcgaggggca ggtggaggta cacttccgag 850

 gggtctggaa cacagtgtgt gacagtgagt ggtacccatc ggaggccaag 900

 gtgctctgcc agtccttggg ctgtggaact gcggttgaga ggcccaaggg 950

 gctgccccac tccttgtccg gcaggatgta ctactcatgc aatggggagg 1000

 agctcaccct ctccaactgc tcctggcggt tcaacaactc caacctctgc 1050

 agccagtcgc tggcagccag ggtcctctgc tcagcttccc ggagtttgca 1100

 caatctgtcc actcccgaag tccctgcaag tgttcagaca gtcactatag 1150

 aatcttctgt gacagtgaaa atagagaaca aggaatctcg ggagctaatg 1200

 ctcctcatcc cctccatcgt tctgggaatt ctcctccttg gctccctcat 1250

 cttcatagcc ttcatcctct tgagaattaa aggaaaatat gccctccccg 1300

 taatggtgaa ccaccagcac ctacccacca ccatcccggc agggagcaat 1350

 agctatcaac cggtccccat caccatcccc aaagaagttt tcatgctgcc 1400

 catccaggtc caggccccgc cccctgagga ctcagactct ggctcggact 1450

 cagactatga gcactatgac ttcagcgccc agcctcctgt ggccctgacc 1500

 accttctaca attcccagcg gcatcgggtc acagatgagg aggtccagca 1550

 aagcaggttc cagatgccac ccttggagga aggacttgaa gagttgcatg 1600

 cctcccacat cccaactgcc aaccctggac actgcattac agacccgcca 1650

 tccctgggcc ctcagtatca cccgaggagc aacagtgagt cgagcacctc 1700

 ttcgggggag gattactgca atagtcccaa aagcaagctg cctccatgga 1750

 acccccaggt gttttcttca gagaggagtt ccttcctgga gcagccccca 1800

 aacttggagc tggccggcac ccagccagcc ttttcagcag ggcccccggc 1850

 tgatgacagc tccagcacct catccgggga gtggtaccag aacttccagc 1900

 caccacccca gcccccttcg gaggagcagt ttggctgtcc agggtccccc 1950

 agccctcagc ctgactccac cgacaacgat gactacgatg acatcagcgc 2000

 agcctaggcc 2010

<210> 2466
<211> 668
<212> PRT
<213> Homo sapien

<400> 2466
 Met Trp Leu Phe Phe Gly Ile Thr Gly Leu Leu Thr Ala Ala Leu
   1               5                  10                  15

 Ser Gly His Pro Ser Pro Ala Pro Pro Asp Gln Leu Asn Thr Ser
                  20                  25                  30

 Ser Ala Glu Ser Glu Leu Trp Glu Pro Gly Glu Arg Leu Pro Val
                  35                  40                  45

 Arg Leu Thr Asn Gly Ser Ser Ser Cys Ser Gly Thr Val Glu Val
                  50                  55                  60

 Arg Leu Glu Ala Ser Trp Glu Pro Ala Cys Gly Ala Leu Trp Asp
                  65                  70                  75

 Ser Arg Ala Ala Glu Ala Val Cys Arg Ala Leu Gly Cys Gly Gly
                  80                  85                  90

 Ala Glu Ala Ala Ser Gln Leu Ala Pro Pro Thr Pro Glu Leu Pro
                  95                 100                 105

 Pro Pro Pro Ala Ala Gly Asn Thr Ser Val Ala Ala Asn Ala Thr
                 110                 115                 120

 Leu Ala Gly Ala Pro Ala Leu Leu Cys Ser Gly Ala Glu Trp Arg
                 125                 130                 135

 Leu Cys Glu Val Val Glu His Ala Cys Arg Ser Asp Gly Arg Arg
                 140                 145                 150

 Ala Arg Val Thr Cys Ala Glu Asn Arg Ala Leu Arg Leu Val Asp
                 155                 160                 165

 Gly Gly Gly Ala Cys Ala Gly Arg Val Glu Met Leu Glu His Gly
                 170                 175                 180

 Glu Trp Gly Ser Val Cys Asp Asp Thr Trp Asp Leu Glu Asp Ala
                 185                 190                 195

 His Val Val Cys Arg Gln Leu Gly Cys Gly Trp Ala Val Gln Ala
                 200                 205                 210

 Leu Pro Gly Leu His Phe Thr Pro Gly Arg Gly Pro Ile His Arg
                 215                 220                 225

 Asp Gln Val Asn Cys Ser Gly Ala Glu Ala Tyr Leu Trp Asp Cys
                 230                 235                 240

 Pro Gly Leu Pro Gly Gln His Tyr Cys Gly His Lys Glu Asp Ala
                 245                 250                 255

 Gly Val Val Cys Ser Glu His Gln Ser Trp Arg Leu Thr Gly Gly
                 260                 265                 270

 Ala Asp Arg Cys Glu Gly Gln Val Glu Val His Phe Arg Gly Val
                 275                 280                 285

 Trp Asn Thr Val Cys Asp Ser Glu Trp Tyr Pro Ser Glu Ala Lys
                 290                 295                 300

 Val Leu Cys Gln Ser Leu Gly Cys Gly Thr Ala Val Glu Arg Pro
                 305                 310                 315

 Lys Gly Leu Pro His Ser Leu Ser Gly Arg Met Tyr Tyr Ser Cys
                 320                 325                 330

 Asn Gly Glu Glu Leu Thr Leu Ser Asn Cys Ser Trp Arg Phe Asn
                 335                 340                 345

 Asn Ser Asn Leu Cys Ser Gln Ser Leu Ala Ala Arg Val Leu Cys
                 350                 355                 360

 Ser Ala Ser Arg Ser Leu His Asn Leu Ser Thr Pro Glu Val Pro
                 365                 370                 375

 Ala Ser Val Gln Thr Val Thr Ile Glu Ser Ser Val Thr Val Lys
                 380                 385                 390

 Ile Glu Asn Lys Glu Ser Arg Glu Leu Met Leu Leu Ile Pro Ser
                 395                 400                 405

 Ile Val Leu Gly Ile Leu Leu Leu Gly Ser Leu Ile Phe Ile Ala
                 410                 415                 420

 Phe Ile Leu Leu Arg Ile Lys Gly Lys Tyr Ala Leu Pro Val Met
                 425                 430                 435

 Val Asn His Gln His Leu Pro Thr Thr Ile Pro Ala Gly Ser Asn
                 440                 445                 450

 Ser Tyr Gln Pro Val Pro Ile Thr Ile Pro Lys Glu Val Phe Met
                 455                 460                 465

 Leu Pro Ile Gln Val Gln Ala Pro Pro Pro Glu Asp Ser Asp Ser
                 470                 475                 480

 Gly Ser Asp Ser Asp Tyr Glu His Tyr Asp Phe Ser Ala Gln Pro
                 485                 490                 495

 Pro Val Ala Leu Thr Thr Phe Tyr Asn Ser Gln Arg His Arg Val
                 500                 505                 510

 Thr Asp Glu Glu Val Gln Gln Ser Arg Phe Gln Met Pro Pro Leu
                 515                 520                 525

 Glu Glu Gly Leu Glu Glu Leu His Ala Ser His Ile Pro Thr Ala
                 530                 535                 540

 Asn Pro Gly His Cys Ile Thr Asp Pro Pro Ser Leu Gly Pro Gln
                 545                 550                 555

 Tyr His Pro Arg Ser Asn Ser Glu Ser Ser Thr Ser Ser Gly Glu
                 560                 565                 570

 Asp Tyr Cys Asn Ser Pro Lys Ser Lys Leu Pro Pro Trp Asn Pro
                 575                 580                 585

 Gln Val Phe Ser Ser Glu Arg Ser Ser Phe Leu Glu Gln Pro Pro
                 590                 595                 600

 Asn Leu Glu Leu Ala Gly Thr Gln Pro Ala Phe Ser Ala Gly Pro
                 605                 610                 615

 Pro Ala Asp Asp Ser Ser Ser Thr Ser Ser Gly Glu Trp Tyr Gln
                 620                 625                 630

 Asn Phe Gln Pro Pro Pro Gln Pro Pro Ser Glu Glu Gln Phe Gly
                 635                 640                 645

 Cys Pro Gly Ser Pro Ser Pro Gln Pro Asp Ser Thr Asp Asn Asp
                 650                 655                 660

 Asp Tyr Asp Asp Ile Ser Ala Ala
                 665

<210> 2467
<211> 1782
<212> DNA
<213> Homo sapien

<400> 2467
 atgtggctct tcttcgggat cactggattg ctgacggcag ccctctcagg 50

 tcatccatct ccagccccac ctgaccagct caacaccagc agtgcagaga 100

 gtgagctctg ggagccaggg gagcggcttc cggtccgtct gacaaacggg 150

 agcagcagct gcagcgggac ggtggaggtg cggctcgagg cgtcctggga 200

 gcccgcgtgc ggggcgctct gggacagccg cgccgccgag gccgtgtgcc 250

 gagcactggg ctgcggcggg gcggaggccg cctctcagct cgccccgccg 300

 acccctgagc tgccgccccc gcctgcagcc gggaacacca gcgtagcagc 350

 taatgccact ctggccgggg cgcccgccct cctgtgcagc ggcgccgagt 400

 ggcggctctg cgaggtggtg gagcacgcgt gccgcagcga cgggaggcgg 450

 gcccgtgtca cctgtgcaga gaaccgcgcg ctgcgcctgg tggacggtgg 500

 cggcgcctgc gccggccgcg tggagatgct ggagcatggc gagtggggat 550

 cagtgtgcga tgacacttgg gacctggagg acgcccacgt ggtgtgcagg 600

 caactgggct gcggctgggc agtccaggcc ctgcccggct tgcacttcac 650

 gcccggccgc gggcctatcc accgggacca ggtgaactgc tcgggggccg 700

 aagcttacct gtgggactgc ccggggctgc caggacagca ctactgcggc 750

 cacaaagagg acgcgggcgt ggtgtgctca gagcaccagt cctggcgcct 800

 gacagggggc gctgaccgct gcgaggggca ggtggaggta cacttccgag 850

 gggtctggaa cacagtgtgt gacagtgagt ggtacccatc ggaggccaag 900

 gtgctctgcc agtccttggg ctgtggaact gcggttgaga ggcccaaggg 950

 gctgccccac tccttgtccg gcaggatgta ctactcatgc aatggggagg 1000

 agctcaccct ctccaactgc tcctggcggt tcaacaactc caacctctgc 1050

 agccagtcgc tggcagccag ggtcctctgc tcagcttccc ggagtttgca 1100

 caatctgtcc actcccgaag tccctgcaag tgttcagaca gtcactatag 1150

 aatcttctgt gacagtgaaa atagagaaca aggaatctcg ggagctaatg 1200

 ctcctcatcc cctccatcgt tctgggaatt ctcctccttg gctccctcat 1250

 cttcatagcc ttcatcctct tgagaattaa aggaaaatat gccctccccg 1300

 taatggtgaa ccaccagcac ctacccacca ccatcccggc agggagcaat 1350

 agctatcaac cggtccccat caccatcccc aaagaagatt cccagcggca 1400

 tcgggtcaca gatgaggagg tccagcaaag caggttccag atgccaccct 1450

 tggaggaagg acttgaagag ttgcatgcct cccacatccc aactgccaac 1500

 cctggacact gcattacaga cccgccatcc ctgggccctc agtatcaccc 1550

 gaggagcaac agtgagtcga gcacctcttc aggggaggat tactgcaata 1600

 gtcccaaaag caagctgcct ccatggaacc cccaggtgtt ttcttcagag 1650

 aggagttcct tcctggagca gcccccaaac ttggagctgg ccggcaccca 1700

 gccagccttt tcagggtccc ccagccctca gcctgactcc accgacaacg 1750

 atgactacga tgacatcagc gcagcctagg cc 1782

<210> 2468
<211> 592
<212> PRT
<213> Homo sapien

<400> 2468
 Met Trp Leu Phe Phe Gly Ile Thr Gly Leu Leu Thr Ala Ala Leu
   1               5                  10                  15

 Ser Gly His Pro Ser Pro Ala Pro Pro Asp Gln Leu Asn Thr Ser
                  20                  25                  30

 Ser Ala Glu Ser Glu Leu Trp Glu Pro Gly Glu Arg Leu Pro Val
                  35                  40                  45

 Arg Leu Thr Asn Gly Ser Ser Ser Cys Ser Gly Thr Val Glu Val
                  50                  55                  60

 Arg Leu Glu Ala Ser Trp Glu Pro Ala Cys Gly Ala Leu Trp Asp
                  65                  70                  75

 Ser Arg Ala Ala Glu Ala Val Cys Arg Ala Leu Gly Cys Gly Gly
                  80                  85                  90

 Ala Glu Ala Ala Ser Gln Leu Ala Pro Pro Thr Pro Glu Leu Pro
                  95                 100                 105

 Pro Pro Pro Ala Ala Gly Asn Thr Ser Val Ala Ala Asn Ala Thr
                 110                 115                 120

 Leu Ala Gly Ala Pro Ala Leu Leu Cys Ser Gly Ala Glu Trp Arg
                 125                 130                 135

 Leu Cys Glu Val Val Glu His Ala Cys Arg Ser Asp Gly Arg Arg
                 140                 145                 150

 Ala Arg Val Thr Cys Ala Glu Asn Arg Ala Leu Arg Leu Val Asp
                 155                 160                 165

 Gly Gly Gly Ala Cys Ala Gly Arg Val Glu Met Leu Glu His Gly
                 170                 175                 180

 Glu Trp Gly Ser Val Cys Asp Asp Thr Trp Asp Leu Glu Asp Ala
                 185                 190                 195

 His Val Val Cys Arg Gln Leu Gly Cys Gly Trp Ala Val Gln Ala
                 200                 205                 210

 Leu Pro Gly Leu His Phe Thr Pro Gly Arg Gly Pro Ile His Arg
                 215                 220                 225

 Asp Gln Val Asn Cys Ser Gly Ala Glu Ala Tyr Leu Trp Asp Cys
                 230                 235                 240

 Pro Gly Leu Pro Gly Gln His Tyr Cys Gly His Lys Glu Asp Ala
                 245                 250                 255

 Gly Val Val Cys Ser Glu His Gln Ser Trp Arg Leu Thr Gly Gly
                 260                 265                 270

 Ala Asp Arg Cys Glu Gly Gln Val Glu Val His Phe Arg Gly Val
                 275                 280                 285

 Trp Asn Thr Val Cys Asp Ser Glu Trp Tyr Pro Ser Glu Ala Lys
                 290                 295                 300

 Val Leu Cys Gln Ser Leu Gly Cys Gly Thr Ala Val Glu Arg Pro
                 305                 310                 315

 Lys Gly Leu Pro His Ser Leu Ser Gly Arg Met Tyr Tyr Ser Cys
                 320                 325                 330

 Asn Gly Glu Glu Leu Thr Leu Ser Asn Cys Ser Trp Arg Phe Asn
                 335                 340                 345

 Asn Ser Asn Leu Cys Ser Gln Ser Leu Ala Ala Arg Val Leu Cys
                 350                 355                 360

 Ser Ala Ser Arg Ser Leu His Asn Leu Ser Thr Pro Glu Val Pro
                 365                 370                 375

 Ala Ser Val Gln Thr Val Thr Ile Glu Ser Ser Val Thr Val Lys
                 380                 385                 390

 Ile Glu Asn Lys Glu Ser Arg Glu Leu Met Leu Leu Ile Pro Ser
                 395                 400                 405

 Ile Val Leu Gly Ile Leu Leu Leu Gly Ser Leu Ile Phe Ile Ala
                 410                 415                 420

 Phe Ile Leu Leu Arg Ile Lys Gly Lys Tyr Ala Leu Pro Val Met
                 425                 430                 435

 Val Asn His Gln His Leu Pro Thr Thr Ile Pro Ala Gly Ser Asn
                 440                 445                 450

 Ser Tyr Gln Pro Val Pro Ile Thr Ile Pro Lys Glu Asp Ser Gln
                 455                 460                 465

 Arg His Arg Val Thr Asp Glu Glu Val Gln Gln Ser Arg Phe Gln
                 470                 475                 480

 Met Pro Pro Leu Glu Glu Gly Leu Glu Glu Leu His Ala Ser His
                 485                 490                 495

 Ile Pro Thr Ala Asn Pro Gly His Cys Ile Thr Asp Pro Pro Ser
                 500                 505                 510

 Leu Gly Pro Gln Tyr His Pro Arg Ser Asn Ser Glu Ser Ser Thr
                 515                 520                 525

 Ser Ser Gly Glu Asp Tyr Cys Asn Ser Pro Lys Ser Lys Leu Pro
                 530                 535                 540

 Pro Trp Asn Pro Gln Val Phe Ser Ser Glu Arg Ser Ser Phe Leu
                 545                 550                 555

 Glu Gln Pro Pro Asn Leu Glu Leu Ala Gly Thr Gln Pro Ala Phe
                 560                 565                 570

 Ser Gly Ser Pro Ser Pro Gln Pro Asp Ser Thr Asp Asn Asp Asp
                 575                 580                 585

 Tyr Asp Asp Ile Ser Ala Ala
                 590

<210> 2469
<211> 1679
<212> DNA
<213> Homo sapien

<400> 2469
 gtttgttggc tgcggcagca ggtagcaaag tgacgccgag ggcctgagtg 50

 ctccagtagc caccgcatct ggagaaccag cggttaccat ggaggggatc 100

 agtatataca cttcagataa ctacaccgag gaaatgggct caggggacta 150

 tgactccatg aaggaaccct gtttccgtga agaaaatgct aatttcaata 200

 aaatcttcct gcccaccatc tactccatca tcttcttaac tggcattgtg 250

 ggcaatggat tggtcatcct ggtcatgggt taccagaaga aactgagaag 300

 catgacggac aagtacaggc tgcacctgtc agtggccgac ctcctctttg 350

 tcatcacgct tcccttctgg gcagttgatg ccgtggcaaa ctggtacttt 400

 gggaacttcc tatgcaaggc agtccatgtc atctacacag tcaacctcta 450

 cagcagtgtc ctcatcctgg ccttcatcag tctggaccgc tacctggcca 500

 tcgtccacgc caccaacagt cagaggccaa ggaagctgtt ggctgaaaag 550

 gtggtctatg ttggcgtctg gatccctgcc ctcctgctga ctattcccga 600

 cttcatcttt gccaacgtca gtgaggcaga tgacagatat atctgtgacc 650

 gcttctaccc caatgacttg tgggtggttg tgttccagtt tcagcacatc 700

 atggttggcc ttatcctgcc tggtattgtc atcctgtcct gctattgcat 750

 tatcatctcc aagctgtcac actccaaggg ccaccagaag cgcaaggccc 800

 tcaagaccac agtcatcctc atcctggctt tcttcgcctg ttggctgcct 850

 tactacattg ggatcagcat cgactccttc atcctcctgg aaatcatcaa 900

 gcaagggtgt gagtttgaga acactgtgca caagtggatt tccatcaccg 950

 aggccctagc tttcttccac tgttgtctga accccatcct ctatgctttc 1000

 cttggagcca aatttaaaac ctctgcccag cacgcactca cctctgtgag 1050

 cagagggtcc agcctcaaga tcctctccaa aggaaagcga ggtggacatt 1100

 catctgtttc cactgagtct gagtcttcaa gttttcactc cagctaacac 1150

 agatgtaaaa gacttttttt tatacgataa ataacttttt tttaagttac 1200

 acatttttca gatataaaag actgaccaat attgtacagt ttttattgct 1250

 tgttggattt ttgtcttgtg tttctttagt ttttgtgaag tttaattgac 1300

 ttatttatat aaattttttt tgtttcatat tgatgtgtgt ctaggcagga 1350

 cctgtggcca agttcttagt tgctgtatgt ctcgtggtag gactgtagaa 1400

 aagggaactg aacattccag agcgtgtagt gaatcacgta aagctagaaa 1450

 tgatccccag ctgtttatgc atagataatc tctccattcc cgtggaacgt 1500

 ttttcctgtt cttaagacgt gattttgctg tagaagatgg cacttataac 1550

 caaagcccaa agtggtatag aaatgctggt ttttcagttt tcaggagtgg 1600

 gttgatttca gcacctacag tgtacagtct tgtattaagt tgttaataaa 1650

 agtacatgtt aaacttactt agtgttatg 1679

<210> 2470
<211> 352
<212> PRT
<213> Homo sapien

<400> 2470
 Met Glu Gly Ile Ser Ile Tyr Thr Ser Asp Asn Tyr Thr Glu Glu
   1               5                  10                  15

 Met Gly Ser Gly Asp Tyr Asp Ser Met Lys Glu Pro Cys Phe Arg
                  20                  25                  30

 Glu Glu Asn Ala Asn Phe Asn Lys Ile Phe Leu Pro Thr Ile Tyr
                  35                  40                  45

 Ser Ile Ile Phe Leu Thr Gly Ile Val Gly Asn Gly Leu Val Ile
                  50                  55                  60

 Leu Val Met Gly Tyr Gln Lys Lys Leu Arg Ser Met Thr Asp Lys
                  65                  70                  75

 Tyr Arg Leu His Leu Ser Val Ala Asp Leu Leu Phe Val Ile Thr
                  80                  85                  90

 Leu Pro Phe Trp Ala Val Asp Ala Val Ala Asn Trp Tyr Phe Gly
                  95                 100                 105

 Asn Phe Leu Cys Lys Ala Val His Val Ile Tyr Thr Val Asn Leu
                 110                 115                 120

 Tyr Ser Ser Val Leu Ile Leu Ala Phe Ile Ser Leu Asp Arg Tyr
                 125                 130                 135

 Leu Ala Ile Val His Ala Thr Asn Ser Gln Arg Pro Arg Lys Leu
                 140                 145                 150

 Leu Ala Glu Lys Val Val Tyr Val Gly Val Trp Ile Pro Ala Leu
                 155                 160                 165

 Leu Leu Thr Ile Pro Asp Phe Ile Phe Ala Asn Val Ser Glu Ala
                 170                 175                 180

 Asp Asp Arg Tyr Ile Cys Asp Arg Phe Tyr Pro Asn Asp Leu Trp
                 185                 190                 195

 Val Val Val Phe Gln Phe Gln His Ile Met Val Gly Leu Ile Leu
                 200                 205                 210

 Pro Gly Ile Val Ile Leu Ser Cys Tyr Cys Ile Ile Ile Ser Lys
                 215                 220                 225

 Leu Ser His Ser Lys Gly His Gln Lys Arg Lys Ala Leu Lys Thr
                 230                 235                 240

 Thr Val Ile Leu Ile Leu Ala Phe Phe Ala Cys Trp Leu Pro Tyr
                 245                 250                 255

 Tyr Ile Gly Ile Ser Ile Asp Ser Phe Ile Leu Leu Glu Ile Ile
                 260                 265                 270

 Lys Gln Gly Cys Glu Phe Glu Asn Thr Val His Lys Trp Ile Ser
                 275                 280                 285

 Ile Thr Glu Ala Leu Ala Phe Phe His Cys Cys Leu Asn Pro Ile
                 290                 295                 300

 Leu Tyr Ala Phe Leu Gly Ala Lys Phe Lys Thr Ser Ala Gln His
                 305                 310                 315

 Ala Leu Thr Ser Val Ser Arg Gly Ser Ser Leu Lys Ile Leu Ser
                 320                 325                 330

 Lys Gly Lys Arg Gly Gly His Ser Ser Val Ser Thr Glu Ser Glu
                 335                 340                 345

 Ser Ser Ser Phe His Ser Ser
                 350

<210> 2471
<211> 2279
<212> DNA
<213> Homo sapien

<400> 2471
 tgcctgctga gggtggagac ccacgagccg aggcctcctg cagtgttctg 50

 cacagcaaac cgcacgctat ggctgacagc cgggatcccg ccagcgacca 100

 gatgcagcac tggaaggagc agcgggccgc gcagaaagct gatgtcctga 150

 ccactggagc tggtaaccca gtaggagaca aacttaatgt tattacagta 200

 gggccccgtg ggccccttct tgttcaggat gtggttttca ctgatgaaat 250

 ggctcatttt gaccgagaga gaattcctga gagagttgtg catgctaaag 300

 gagcaggggc ctttggctac tttgaggtca cacatgacat taccaaatac 350

 tccaaggcaa aggtatttga gcatattgga aagaagactc ccatcgcagt 400

 tcggttctcc actgttgctg gagaatcggg ttcagctgac acagttcggg 450

 accctcgtgg gtttgcagtg aaattttaca cagaagatgg taactgggat 500

 ctcgttggaa ataacacccc cattttcttc atcagggatc ccatattgtt 550

 tccatctttt atccacagcc aaaagagaaa tcctcagaca catctgaagg 600

 atccggacat ggtctgggac ttctggagcc tacgtcctga gtctctgcat 650

 caggtttctt tcttgttcag tgatcggggg attccagatg gacatcgcca 700

 catgaatgga tatggatcac atactttcaa gctggttaat gcaaatgggg 750

 aggcagttta ttgcaaattc cattataaga ctgaccaggg catcaaaaac 800

 ctttctgttg aagatgcggc gagactttcc caggaagatc ctgactatgg 850

 catccgggat ctttttaacg ccattgccac aggaaagtac ccctcctgga 900

 ctttttacat ccaggtcatg acatttaatc aggcagaaac ttttccattt 950

 aatccattcg atctcaccaa ggtttggcct cacaaggact accctctcat 1000

 cccagttggt aaactggtct taaaccggaa tccagttaat tactttgctg 1050

 aggttgaaca gatagccttc gacccaagca acatgccacc tggcattgag 1100

 gccagtcctg acaaaatgct tcagggccgc ctttttgcct atcctgacac 1150

 tcaccgccat cgcctgggac ccaattatct tcatatacct gtgaactgtc 1200

 cctaccgtgc tcgagtggcc aactaccagc gtgatggccc gatgtgcatg 1250

 caggacaatc agggtggtgc tccaaattac taccccaaca gctttggtgc 1300

 tccggaacaa cagccttctg ccctggagca cagcatccaa tattctggag 1350

 aagtgcggag attcaacact gccaatgatg ataacgttac tcaggtgcgg 1400

 gcattctatg tgaacgtgct gaatgaggaa cagaggaaac gtctgtgtga 1450

 gaacattgcc ggccacctga aggatgcaca aattttcatc cagaagaaag 1500

 cggtcaagaa cttcactgag gtccaccctg actacgggag ccacatccag 1550

 gctcttctgg acaagtacaa tgctgagaag cctaagaatg cgattcacac 1600

 ctttgtgcag tccggatctc acttggcggc aagggagaag gcaaatctgt 1650

 gaggccgggg ccctgcacct gtgcagcgaa gcttagcgtt catccgtgta 1700

 acccgctcat cactggatga agattctcct gtgctagatg tgcaaatgca 1750

 agctagtggc ttcaaaatag agaatcccac tttctatagc agattgtgta 1800

 acaattttaa tgctatttcc ccaggggaaa atgaaggtta ggatttaaca 1850

 gtcatttaaa aaaaaaattt gttttgacgg atgattggat tattcattta 1900

 aaatgattag aaggcaagtt tctagctaga aatatgattt tatttgacaa 1950

 aatttgttga aattatgtat gtttacatat cacctcatgg cctattatat 2000

 taaaatatgg ctataaatat ataaaaagaa aagataaaga tgatctactc 2050

 agaaattttt atttttctaa ggttctcata ggaaaagtac atttaataca 2100

 gcagtgtcat cagaagataa cttgagcacc gtcatggctt aatgtttatt 2150

 cctgataata attgatcaaa ttcatttttt tcactggagt tacattaatg 2200

 ttaattcagc actgatttca caacagatca atttgtaatt gcttacattt 2250

 ttacaataaa taatctgtac gtaagaaca 2279

<210> 2472
<211> 527
<212> PRT
<213> Homo sapien

<400> 2472
 Met Ala Asp Ser Arg Asp Pro Ala Ser Asp Gln Met Gln His Trp
   1               5                  10                  15

 Lys Glu Gln Arg Ala Ala Gln Lys Ala Asp Val Leu Thr Thr Gly
                  20                  25                  30

 Ala Gly Asn Pro Val Gly Asp Lys Leu Asn Val Ile Thr Val Gly
                  35                  40                  45

 Pro Arg Gly Pro Leu Leu Val Gln Asp Val Val Phe Thr Asp Glu
                  50                  55                  60

 Met Ala His Phe Asp Arg Glu Arg Ile Pro Glu Arg Val Val His
                  65                  70                  75

 Ala Lys Gly Ala Gly Ala Phe Gly Tyr Phe Glu Val Thr His Asp
                  80                  85                  90

 Ile Thr Lys Tyr Ser Lys Ala Lys Val Phe Glu His Ile Gly Lys
                  95                 100                 105

 Lys Thr Pro Ile Ala Val Arg Phe Ser Thr Val Ala Gly Glu Ser
                 110                 115                 120

 Gly Ser Ala Asp Thr Val Arg Asp Pro Arg Gly Phe Ala Val Lys
                 125                 130                 135

 Phe Tyr Thr Glu Asp Gly Asn Trp Asp Leu Val Gly Asn Asn Thr
                 140                 145                 150

 Pro Ile Phe Phe Ile Arg Asp Pro Ile Leu Phe Pro Ser Phe Ile
                 155                 160                 165

 His Ser Gln Lys Arg Asn Pro Gln Thr His Leu Lys Asp Pro Asp
                 170                 175                 180

 Met Val Trp Asp Phe Trp Ser Leu Arg Pro Glu Ser Leu His Gln
                 185                 190                 195

 Val Ser Phe Leu Phe Ser Asp Arg Gly Ile Pro Asp Gly His Arg
                 200                 205                 210

 His Met Asn Gly Tyr Gly Ser His Thr Phe Lys Leu Val Asn Ala
                 215                 220                 225

 Asn Gly Glu Ala Val Tyr Cys Lys Phe His Tyr Lys Thr Asp Gln
                 230                 235                 240

 Gly Ile Lys Asn Leu Ser Val Glu Asp Ala Ala Arg Leu Ser Gln
                 245                 250                 255

 Glu Asp Pro Asp Tyr Gly Ile Arg Asp Leu Phe Asn Ala Ile Ala
                 260                 265                 270

 Thr Gly Lys Tyr Pro Ser Trp Thr Phe Tyr Ile Gln Val Met Thr
                 275                 280                 285

 Phe Asn Gln Ala Glu Thr Phe Pro Phe Asn Pro Phe Asp Leu Thr
                 290                 295                 300

 Lys Val Trp Pro His Lys Asp Tyr Pro Leu Ile Pro Val Gly Lys
                 305                 310                 315

 Leu Val Leu Asn Arg Asn Pro Val Asn Tyr Phe Ala Glu Val Glu
                 320                 325                 330

 Gln Ile Ala Phe Asp Pro Ser Asn Met Pro Pro Gly Ile Glu Ala
                 335                 340                 345

 Ser Pro Asp Lys Met Leu Gln Gly Arg Leu Phe Ala Tyr Pro Asp
                 350                 355                 360

 Thr His Arg His Arg Leu Gly Pro Asn Tyr Leu His Ile Pro Val
                 365                 370                 375

 Asn Cys Pro Tyr Arg Ala Arg Val Ala Asn Tyr Gln Arg Asp Gly
                 380                 385                 390

 Pro Met Cys Met Gln Asp Asn Gln Gly Gly Ala Pro Asn Tyr Tyr
                 395                 400                 405

 Pro Asn Ser Phe Gly Ala Pro Glu Gln Gln Pro Ser Ala Leu Glu
                 410                 415                 420

 His Ser Ile Gln Tyr Ser Gly Glu Val Arg Arg Phe Asn Thr Ala
                 425                 430                 435

 Asn Asp Asp Asn Val Thr Gln Val Arg Ala Phe Tyr Val Asn Val
                 440                 445                 450

 Leu Asn Glu Glu Gln Arg Lys Arg Leu Cys Glu Asn Ile Ala Gly
                 455                 460                 465

 His Leu Lys Asp Ala Gln Ile Phe Ile Gln Lys Lys Ala Val Lys
                 470                 475                 480

 Asn Phe Thr Glu Val His Pro Asp Tyr Gly Ser His Ile Gln Ala
                 485                 490                 495

 Leu Leu Asp Lys Tyr Asn Ala Glu Lys Pro Lys Asn Ala Ile His
                 500                 505                 510

 Thr Phe Val Gln Ser Gly Ser His Leu Ala Ala Arg Glu Lys Ala
                 515                 520                 525

 Asn Leu


<210> 2473
<211> 2620
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1109-1286
<223> Unknown base

<400> 2473
 ttcggctcga ggcactacac cgtggcaggt actgctgcag ggcagggtgc 50

 agaggatgaa agaaatctta atacttatca ctgtcatagc caacagcgtt 100

 gtaggaaact acataataaa atactgttat attacttcat atatattaaa 150

 gaaaatgggt catgtgggtc aacccatgtt tttacatgta aaataatcgt 200

 tcctgacaaa taagaacatt gatacatgag gggcccatat gtatgtctct 250

 aggaagaaaa tatgtctcta ggaagaaaat tgtgccatat gtaccggcat 300

 ggactaaggc agaaaaagct gtgtatcagt aggtagatac atttcaggct 350

 atggtggtgg tggaccagga tatggaaacc aaggtggtgg atatggtgga 400

 ggtggaggat atgatggtta caatgaagga ggaaattttg gcggtggtaa 450

 ctatggtggt ggtgggaact ataatgattt tggaaattat agtggacaac 500

 agcaatcaaa ttatggaccc atgaaagggg gcagttttgg tggaagaagc 550

 tcgggcagtc cctatggtgg tggttatgga tctggtggtg gaagtggtgg 600

 atatggtagc agaaggttct aaaaacagca gaaaagggtt gaatgagaac 650

 cctacttgcc taaatgagga atgtctttcc taccatctaa aatacgaagg 700

 tttctggctg ggtaaggttt gtagttgaca gtaaaacctg atgacaccat 750

 ttgtttccct gcaagtctac attacatatt tcacaacttt gtccctctct 800

 agtaggcaca ttggaaaaat tcttcaactg aaaactacct tggtaccatg 850

 tcctacacgt ttttttttaa accttagttt taaaaattcc cctgcgaaat 900

 agccataagt attcatatca agtcagttgt gactccttgt gtatacaatt 950

 cattttttgt gtcttcaggg taaactcaat ttttggtaaa gtggtttcag 1000

 cttttgtgaa aaccgttttt gtgtgtaagc atgacacaca acagactcag 1050

 taagctgccc atcctcatac taggaaaaca ccttcaaagg aacattaaaa 1100

 gttaccagnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1150

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnctag cgcttgatat 1300

 caggcagtcg aggctggcag tgagctgact gccccactgt attccagcct 1350

 gggtgacccc atctcaaaga agaaaagtta ccagatgtca tgggtaaagg 1400

 ttggtcttca agtggcctca taagttgtct tgcatttaaa ttcagggaat 1450

 tcattggacc aataggttac attttcgttc cttttttgtt ttggttcatc 1500

 tgttaagcag tgggggccta attactgctc ctttgtaaaa acacattttc 1550

 ccaaagaaca ctgaattacc gttcaaactg gttgttgatg ggtaataagg 1600

 gctgtttttg ctgccccaaa agggcttaac aatttaggcg gatagtttac 1650

 ttaaaaaaaa aaatcctttg gagacatact gaaaatgcaa actagtttct 1700

 aaattatcaa ttccctacat gaagaagcag tttgccagag tttagtctca 1750

 gaaaatgact ggttggctct atttaaatca gaacccaatt tctacgcgtg 1800

 ttgaataagg taacagcctt tgatgaattt ccttcacaac atggttttag 1850

 tgaagcaaac attttttttt taagggcatt gttctttcta gtttatttct 1900

 ttttatgaaa taaaattatt ttatttaaac agttccattg tcgtttctga 1950

 aaactacagt attctcagaa gttgtagcag cagtaaaaaa aaaaaagttg 2000

 ttctataagt gattggggca gatttaactg attttgttaa accaatttgt 2050

 aagttactgc ttctaatatt acacttctaa aaagctgaat ttatactcat 2100

 gtcctaaagg agaatatgtg gtaataaagt atatttgtta agtaactaat 2150

 tgaaataggc ttggttttaa gagttccagt atataataat cacaaattga 2200

 aacctgacag tatcttggga gttccagtaa tgtcacaaat tagtgaataa 2250

 gcatgccagt gtgcaagggt aatgtaagga ttgttagcct atctaaatat 2300

 tcaaaattac tttaaaactt aagtatgttt tctgattttt aagaattcag 2350

 aagtgttctg taatggattc agatgtttca tttgtagtat aatgaaatgt 2400

 ttacagaaag ataacttttt cattaaaata tttttagaaa tgtgtgtgtt 2450

 gttttgtcac ttcacaatgt tcatgtgact taaacactat aggtgaatat 2500

 tttgacttat tttaccagta agtaataaaa caacaggaaa cttggaaaaa 2550

 aaatctatgt cgggtgcgga gaaagaggta atgaaatggc aggaattcga 2600

 tatcagctta tcggataccg 2620

<210> 2474
<211> 88
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 27-86
<223> unknown amino acid

<220>
<221> Unsure
<222> 1109-1286
<223> Unknown amino acid

<400> 2474
 Met Thr His Asn Arg Leu Ser Lys Leu Pro Ile Leu Ile Leu Gly
   1               5                  10                  15

 Lys His Leu Gln Arg Asn Ile Lys Ser Tyr Gln Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ser Ala
                  80                  85

<210> 2475
<211> 3727
<212> DNA
<213> Homo sapien

<400> 2475
 cggccgccgg cattcgccgc gtggttccca gcgacctgta tcccctcgtg 50

 ctcggcttcc tgcgcgataa ccaactctca gaggtggcca ataagttcgc 100

 caaagcgaca ggagctacac agcaggatgc caatgcctct tccctcttag 150

 acatctatag cttctggctc aagtctgcca aggtcccaga gcgaaagtta 200

 caggcaaatg gaccagtggc taagaaagct aagaagaagg cctcatccag 250

 tgacagtgag gacagcagcg aggaggagga ggaagttcaa gggcctccag 300

 caaagaaggc tgctgtacct gccaagcgag tcggtctgcc tcctgggaag 350

 gctgcagcca aagcatcaga gagtagcagc agtgaagagt ccagtgatga 400

 tgatgatgag gaggaccaaa agaaacagcc tgtccagaag ggagttaagc 450

 cccaagccaa ggcagccaaa gctcctccta agaaggccaa gagctctgat 500

 tctgattctg actcaagctc cgaggatgag ccaccaaaga accagaagcc 550

 aaagataaca cctgtgacag ttaaagctca gactaaagcc cctcccaaac 600

 cagctcgagc agcacctaaa atagccaatg gtaaagcagc cagtagcagc 650

 agtagcagca gcagcagcag tagcagtgat gactcagagg aggagaaggc 700

 agcagccacc cccaagaagg tctggaccat aacttctgtc agggcagaga 750

 ctgtacctaa aaagcaagtt gtggccaagg ccccagtgaa agcagctacc 800

 acccctaccc ggaagagttc tagcagtgag gattcctcca gtgacgagga 850

 agaggagcaa aaaaaaccca tgaaaaataa accaggtccc tacagttcag 900

 tccccccgcc ttctgctccc ccaccaaaga agtctctggg aacccagcct 950

 cccaagaagg ctgtggagaa gcagcagcct gtggaaagca gtgaagacag 1000

 cagtgatgag tctgattcaa gttctgaaga agagaagaaa cccccaacta 1050

 aggcagtagt ctctaaagca accactaaac cacctccagc aaagaaagca 1100

 gcagagagct cttcagacag ctcagactct gacagctctg aggatgatga 1150

 agctccttct aagccagctg gtaccaccaa gaattcttca aataagccag 1200

 ctgtcaccac caagtcacct gcagtgaagc cagctgcagc ccccaagcaa 1250

 cctgtgggcg gtggccagaa gcttctgacg agaaaggctg acagcagctc 1300

 cagtgaggaa gagagcagct ccagtgagga ggagaagaca aagaagatgg 1350

 tggccaccac taagcccaag gcgactgcca aagcagctct acctctgcct 1400

 gccaagcagg ctcctcaggg tagtagggac agcagctctg attcagacag 1450

 ctccagcagt gaggaggagg aagagaagac atctaagtct gcagttaaga 1500

 agaagccaca gaaggtagca ggaggtgcag ccccttccaa gccagcctct 1550

 gcaaagaaag gaaaggctga gagcagcaac agttcttctt ctgatgactc 1600

 cagtgaggaa gaggaagaga agctcaaggg caagggctct ccaagaccac 1650

 aagcccccaa ggccaatggc acctctgcac tgactgccca gaatggaaaa 1700

 gcagctaaga acagtgagga ggaggaagaa gaaaagaaaa aggcggcagt 1750

 ggtagtttcc aaatcaggtt cattaaagaa gcggaagcag aatgaggctg 1800

 ccaaggaggc agagactcct caggccaaga agataaagct tcagacccct 1850

 aacacatttc caaaaaggaa gaaaggagaa aaaagggcat catccccatt 1900

 ccgaagggtc agggaggagg aaattgaggt ggattcacga gttgcggaca 1950

 actcctttga tgccaagcga ggtgcagccg gagactgggg agagcgagcc 2000

 aatcaggttt tgaagttcac caaaggcaag tcctttcggc atgagaaaac 2050

 caagaagaag cggggcagct accggggagg ctcaatctct gtccaggtca 2100

 attctattaa gtttgacagc gagtgacctg aggccatctt cggtgaagca 2150

 agggtgatga tcggagacta cttactttct ccagtggacc tgggaaccct 2200

 caggtctcta ggtgagggtc ttgatgagga cagaagttta gagtaggtcc 2250

 taagacttta cagtgtaaca tcctctctgg tccttttctg tgttcctagt 2300

 tttgtacaga cttgtttttg agtgttgagt agcagggaca aaataaggga 2350

 atgttatttt ttaagaaaat tcattttcat tgttgtctcc ttccttttct 2400

 gtgaaagtcc tcatactgag aaatttgtat attttatatt aaatcactta 2450

 ctattgattt ttgttgtgat tttcaaaggt ggattcccac agataaaatc 2500

 ttggctattg cccaaaacat agtaaagggt cacgtgtgac tttttataat 2550

 aggaagaaaa ttctgccttt gtgagtgcac atgtccacat ttcatccctc 2600

 cttccctcaa aaccctagag aggggcatta aagaattgtt gatgtatatg 2650

 caatgtctgt taagcatgca ctatgtattt catcctcatt tattgggtct 2700

 gggactgaag tttttagcca gcatggacct aacctacttt ttgggataaa 2750

 attctctgtt ttgttacagg caaaattctg gtatggcgtg aatgccatgg 2800

 gtcattctga atatattttt ttctgtaatt ttatcattac acgatgtttg 2850

 caatacgtgc tttgtttttt aatttgaaag caaacttttc tactgttgaa 2900

 agacattttt tgacaacttg acccttccta gtattgagtt ctaagttgag 2950

 gactgcatct tctcgttttt tacagtatag agaacaaaat gacattagtt 3000

 tgaaaaatac atatcacttg gtattgctgt cttggttgca gtggtgatac 3050

 agaattggtt tcattaattc ctacatggtt gagaatcact gatcaagaaa 3100

 gtggggggaa aaaaaacaaa cgttaaaacc tcaatcctca gtaggaaggt 3150

 agattacatt aggtgaaatt ataggtaatc tatgtatgtg ctaatggggt 3200

 tggaaagaac cttacagagc atattacctg ataaactgga gtgggtttgg 3250

 gagaacaaac taataggatt attgtgtctc ctagttggta cctgggagca 3300

 attgacatgc ccccttcaga accttaactg ttagtagcag tggctgtaac 3350

 aacacaaacc agtgaccaga gataacagct tttaggccaa gctggcctga 3400

 cggtatggct gcaggaagtg actgagcagt agcggtactc agccagacca 3450

 agacggagag ggaagagtcc acagctttct ggaagctaag gcattctggt 3500

 ggtagaaaag tgtgccccaa gccttcatgg acgagttata ggtcttaaga 3550

 ttagtctcct cttgtttgga ttccatactt gctaaataac ctgataataa 3600

 cctggttttc catgtaactg cctctaggaa gaaaatgtac tgttcatgct 3650

 gacacagata tttcagtctg catggtaaaa gttctaaatc ttactacaaa 3700

 ataataaact ggctggttta taatgtg 3727

<210> 2476
<211> 2259
<212> DNA
<213> Homo sapien

<400> 2476
 cagttgcttc agcgtcccgg tgtggctgtg ccgttggtcc tgtgcggtca 50

 cttagccaag atgcctgagg aaacccagac ccaagaccaa ccgatggagg 100

 aggaggaggt tgagacgttc gcctttcagg cagaaattgc ccagttgatg 150

 tcattgatca tcaatacttt ctactcgaac aaagagatct ttctgagaga 200

 gctcatttca aattcatcag atgcattgga caaaatccgg tatgaaagct 250

 tgacagatcc cagtaaatta gactctggga aagagctgca tattaacctt 300

 ataccgaaca aacaagatcg aactctcact attgtggata ctggaattgg 350

 aatgaccaag gctgacttga tcaataacct tggtactatc gccaagtctg 400

 ggaccaaagc gttcatggaa gctttgcagg ctggtgcaga tatctctatg 450

 attggccagt tcggtgttgg tttttattct gcttatttgg ttgctgagaa 500

 agtaactgtg atcaccaaac ataacgatga tgagcagtac gcttgggagt 550

 cctcagcagg gggatcattc acagtgagga cagacacagg tgaacctatg 600

 ggtcgtggaa caaaagttat cctacacctg aaagaagacc aaactgagta 650

 cttggaggaa cgaagaataa aggagattgt gaagaaacat tctcagttta 700

 ttggatatcc cattactctt tttgtggaga aggaacgtga taaagaagta 750

 agcgatgatg aggctgaaga aaaggaagac aaagaagaag aaaaagaaaa 800

 agaagagaaa gagtcggaag acaaacctga aattgaagat gttggttctg 850

 atgaggaaga agaaaagaag gatggtgaca agaagaagaa gaagaagatt 900

 aaggaaaagt acatcgatca agaagagctc aacaaaacaa agcccatctg 950

 gaccagaaat cccgacgata ttactaatga ggagtacgga gaattctata 1000

 agagcttgac caatgactgg gaagatcact tggcagtgaa gcatttttca 1050

 gttgaaggac agttggaatt cagagccctt ctatttgtcc cacgacgtgc 1100

 tccttttgat ctgtttgaaa acagaaagaa aaagaacaac atcaaattgt 1150

 atgtacgcag agttttcatc atggataact gtgaggagct aatccctgaa 1200

 tatctgaact tcattagagg ggtggtagac tcggaggatc tccctctaaa 1250

 catatcccgt gagatgttgc aacaaagcaa aattttgaaa gttatcagga 1300

 agaatttggt caaaaaatgc ttagaactct ttactgaact ggcggaagat 1350

 aaagagaact acaagaaatt ctatgagcag ttctctaaaa acataaagct 1400

 tggaatacac gaagactctc aaaatcggaa gaagctttca gagctgttaa 1450

 ggtactacac atctgcctct ggtgatgaga tggtttctct caaggactac 1500

 tgcaccagaa tgaaggagaa ccagaaacat atctattata tcacaggtga 1550

 gaccaaggac caggtagcta actcagcctt tgtggaacgt cttcggaaac 1600

 atggcttaga agtgatctat atgattgagc ccattgatga gtactgtgtc 1650

 caacagctga aggaatttga ggggaagact ttagtgtcag tcaccaaaga 1700

 aggcctggaa cttccagagg atgaagaaga gaaaaagaag caggaagaga 1750

 aaaaaacaaa gtttgagaac ctctgcaaaa tcatgaaaga catattggag 1800

 aaaaaagttg aaaaggtggt tgtgtcaaac cgattggtga catctccatg 1850

 ctgtattgtc acaagcacat atggctggac agcaaacatg gagagaatca 1900

 tgaaagctca agccctaaga gacaactcaa caatgggtta catggcagca 1950

 aagaaacacc tggagataaa ccctgaccat tccattattg agaccttaag 2000

 gcaaaaggca gaggctgata agaacgacaa gtctgtgaag gatctggtca 2050

 tcttgcttta tgaaactgcg ctcctgtctt ctggcttcag tctggaagat 2100

 ccccagacac atgctaacag gatctacagg atgatcaaac ttggtctggg 2150

 tattgatgaa gatgacccta ctgctgatga taccagtgct gctgtaactg 2200

 aagaaatgcc accccttgaa ggagatgacg acacatcacg catggaagaa 2250

 gtagactaa 2259

<210> 2477
<211> 732
<212> PRT
<213> Homo sapien

<400> 2477
 Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu
   1               5                  10                  15

 Glu Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met
                  20                  25                  30

 Ser Leu Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu
                  35                  40                  45

 Arg Glu Leu Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Arg
                  50                  55                  60

 Tyr Glu Ser Leu Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu
                  65                  70                  75

 Leu His Ile Asn Leu Ile Pro Asn Lys Gln Asp Arg Thr Leu Thr
                  80                  85                  90

 Ile Val Asp Thr Gly Ile Gly Met Thr Lys Ala Asp Leu Ile Asn
                  95                 100                 105

 Asn Leu Gly Thr Ile Ala Lys Ser Gly Thr Lys Ala Phe Met Glu
                 110                 115                 120

 Ala Leu Gln Ala Gly Ala Asp Ile Ser Met Ile Gly Gln Phe Gly
                 125                 130                 135

 Val Gly Phe Tyr Ser Ala Tyr Leu Val Ala Glu Lys Val Thr Val
                 140                 145                 150

 Ile Thr Lys His Asn Asp Asp Glu Gln Tyr Ala Trp Glu Ser Ser
                 155                 160                 165

 Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Thr Gly Glu Pro Met
                 170                 175                 180

 Gly Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu Asp Gln Thr
                 185                 190                 195

 Glu Tyr Leu Glu Glu Arg Arg Ile Lys Glu Ile Val Lys Lys His
                 200                 205                 210

 Ser Gln Phe Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys Glu
                 215                 220                 225

 Arg Asp Lys Glu Val Ser Asp Asp Glu Ala Glu Glu Lys Glu Asp
                 230                 235                 240

 Lys Glu Glu Glu Lys Glu Lys Glu Glu Lys Glu Ser Glu Asp Lys
                 245                 250                 255

 Pro Glu Ile Glu Asp Val Gly Ser Asp Glu Glu Glu Glu Lys Lys
                 260                 265                 270

 Asp Gly Asp Lys Lys Lys Lys Lys Lys Ile Lys Glu Lys Tyr Ile
                 275                 280                 285

 Asp Gln Glu Glu Leu Asn Lys Thr Lys Pro Ile Trp Thr Arg Asn
                 290                 295                 300

 Pro Asp Asp Ile Thr Asn Glu Glu Tyr Gly Glu Phe Tyr Lys Ser
                 305                 310                 315

 Leu Thr Asn Asp Trp Glu Asp His Leu Ala Val Lys His Phe Ser
                 320                 325                 330

 Val Glu Gly Gln Leu Glu Phe Arg Ala Leu Leu Phe Val Pro Arg
                 335                 340                 345

 Arg Ala Pro Phe Asp Leu Phe Glu Asn Arg Lys Lys Lys Asn Asn
                 350                 355                 360

 Ile Lys Leu Tyr Val Arg Arg Val Phe Ile Met Asp Asn Cys Glu
                 365                 370                 375

 Glu Leu Ile Pro Glu Tyr Leu Asn Phe Ile Arg Gly Val Val Asp
                 380                 385                 390

 Ser Glu Asp Leu Pro Leu Asn Ile Ser Arg Glu Met Leu Gln Gln
                 395                 400                 405

 Ser Lys Ile Leu Lys Val Ile Arg Lys Asn Leu Val Lys Lys Cys
                 410                 415                 420

 Leu Glu Leu Phe Thr Glu Leu Ala Glu Asp Lys Glu Asn Tyr Lys
                 425                 430                 435

 Lys Phe Tyr Glu Gln Phe Ser Lys Asn Ile Lys Leu Gly Ile His
                 440                 445                 450

 Glu Asp Ser Gln Asn Arg Lys Lys Leu Ser Glu Leu Leu Arg Tyr
                 455                 460                 465

 Tyr Thr Ser Ala Ser Gly Asp Glu Met Val Ser Leu Lys Asp Tyr
                 470                 475                 480

 Cys Thr Arg Met Lys Glu Asn Gln Lys His Ile Tyr Tyr Ile Thr
                 485                 490                 495

 Gly Glu Thr Lys Asp Gln Val Ala Asn Ser Ala Phe Val Glu Arg
                 500                 505                 510

 Leu Arg Lys His Gly Leu Glu Val Ile Tyr Met Ile Glu Pro Ile
                 515                 520                 525

 Asp Glu Tyr Cys Val Gln Gln Leu Lys Glu Phe Glu Gly Lys Thr
                 530                 535                 540

 Leu Val Ser Val Thr Lys Glu Gly Leu Glu Leu Pro Glu Asp Glu
                 545                 550                 555

 Glu Glu Lys Lys Lys Gln Glu Glu Lys Lys Thr Lys Phe Glu Asn
                 560                 565                 570

 Leu Cys Lys Ile Met Lys Asp Ile Leu Glu Lys Lys Val Glu Lys
                 575                 580                 585

 Val Val Val Ser Asn Arg Leu Val Thr Ser Pro Cys Cys Ile Val
                 590                 595                 600

 Thr Ser Thr Tyr Gly Trp Thr Ala Asn Met Glu Arg Ile Met Lys
                 605                 610                 615

 Ala Gln Ala Leu Arg Asp Asn Ser Thr Met Gly Tyr Met Ala Ala
                 620                 625                 630

 Lys Lys His Leu Glu Ile Asn Pro Asp His Ser Ile Ile Glu Thr
                 635                 640                 645

 Leu Arg Gln Lys Ala Glu Ala Asp Lys Asn Asp Lys Ser Val Lys
                 650                 655                 660

 Asp Leu Val Ile Leu Leu Tyr Glu Thr Ala Leu Leu Ser Ser Gly
                 665                 670                 675

 Phe Ser Leu Glu Asp Pro Gln Thr His Ala Asn Arg Ile Tyr Arg
                 680                 685                 690

 Met Ile Lys Leu Gly Leu Gly Ile Asp Glu Asp Asp Pro Thr Ala
                 695                 700                 705

 Asp Asp Thr Ser Ala Ala Val Thr Glu Glu Met Pro Pro Leu Glu
                 710                 715                 720

 Gly Asp Asp Asp Thr Ser Arg Met Glu Glu Val Asp
                 725                 730

<210> 2478
<211> 1857
<212> DNA
<213> Homo sapien

<400> 2478
 ggtttccagg gaaggcagcg agcaggatcc cctactctgc gggcggcgcg 50

 aggcgtctgg ctcttcgcgg cggcggcgag gggaaaggga gcgcgggggc 100

 tgggtggaat cgaggagtga ggaaaaaggg aaggggcggg ggagagggac 150

 cagggaaggc gtcgggggga atctcgcgag ggttggagtt ttggcgagag 200

 tttgtggaag atggcgcctg ttgtgacagg gaaatttggt gagcggcctc 250

 cacctaaacg acttactagg gaagctatgc gaaattattt aaaagagcga 300

 ggggatcaaa cagtacttat tcttcatgca aaagttgcac agaagtcata 350

 tggaaatgaa aaaaggtttt tttgcccacc tccttgtgta tatcttatgg 400

 gcagtggatg gaagaaaaaa aaagaacaaa tggaacgcga tggttgttct 450

 gaacaagagt ctcaaccgtg tgcatttatt gggataggaa atagtgacca 500

 agaaatgcag cagctaaact tggaaggaaa gaactattgc acagccaaaa 550

 cattgtatat atctgactca gacaagcgaa agcacttcat gttgtctgta 600

 aagatgttct atggcaacag tgatgacatt ggtgtgttcc tcagcaagcg 650

 gataaaagtc atctccaaac cttccaaaaa gaagcagtca ttgaaaaatg 700

 ctgacttatg cattgcctca ggaacaaagg tggctctgtt taatcgacta 750

 cgatcccaga cagttagtac cagatacttg catgtagaag gaggtaattt 800

 tcatgccagt tcacagcagt ggggagcctt ttttattcat ctcttggatg 850

 atgatgaatc agaaggagaa gaattcacag tccgagatgg ctacatccat 900

 tatggacaaa cagtcaaact tgtgtgctca gttactggca tggcactccc 950

 aagattgata attaggaaag ttgataagca gaccgcatta ttggatgcag 1000

 atgatcctgt gtcacaactc cataaatgtg cattttacct taaggataca 1050

 gaaagaatgt atttgtgcct ttctcaagaa agaataattc aatttcaggc 1100

 cactccatgt ccaaaagaac caaataaaga gatgataaat gatggcgctt 1150

 cctggacaat cattagcaca gataaggcag agtatacatt ttatgaggga 1200

 atgggccctg tccttgcccc agtcactcct gtgcctgtgg tagagagcct 1250

 tcagttgaat ggcggtgggg acgtagcaat gcttgaactt acaggacaga 1300

 atttcactcc aaatttacga gtgtggtttg gggatgtaga agctgaaact 1350

 atgtacaggt gtggagagag tatgctctgt gtcgtcccag acatttctgc 1400

 attccgagaa ggttggagat gggtccggca accagtccag gttccagtaa 1450

 ctttggtccg aaatgatgga atcatttatt ccaccagcct tacctttacc 1500

 tacacaccag aaccagggcc gcggccacat tgcagtgcag caggagcaat 1550

 ccttcgagcc aattcaagcc aggtgccccc taacgaatca aacacaaaca 1600

 gcgagggaag ttacacaaac gccagcacaa attcaaccag tgtcacatca 1650

 tctacagcca cagtggtatc ctaactaccg tctttttgct aggacttaaa 1700

 ctgacttgag tgtggcaaaa agttaacaaa aaaggagaaa aaatgaacaa 1750

 tcgtttgtgg tttcttggga aaacttttca taccaggtga tactattcaa 1800

 aaaccccgtt gtctccctgc aagtgctgat ttgaaatgca gaagccacag 1850

 taaaaaa 1857

<210> 2479
<211> 487
<212> PRT
<213> Homo sapien

<400> 2479
 Met Ala Pro Val Val Thr Gly Lys Phe Gly Glu Arg Pro Pro Pro
   1               5                  10                  15

 Lys Arg Leu Thr Arg Glu Ala Met Arg Asn Tyr Leu Lys Glu Arg
                  20                  25                  30

 Gly Asp Gln Thr Val Leu Ile Leu His Ala Lys Val Ala Gln Lys
                  35                  40                  45

 Ser Tyr Gly Asn Glu Lys Arg Phe Phe Cys Pro Pro Pro Cys Val
                  50                  55                  60

 Tyr Leu Met Gly Ser Gly Trp Lys Lys Lys Lys Glu Gln Met Glu
                  65                  70                  75

 Arg Asp Gly Cys Ser Glu Gln Glu Ser Gln Pro Cys Ala Phe Ile
                  80                  85                  90

 Gly Ile Gly Asn Ser Asp Gln Glu Met Gln Gln Leu Asn Leu Glu
                  95                 100                 105

 Gly Lys Asn Tyr Cys Thr Ala Lys Thr Leu Tyr Ile Ser Asp Ser
                 110                 115                 120

 Asp Lys Arg Lys His Phe Met Leu Ser Val Lys Met Phe Tyr Gly
                 125                 130                 135

 Asn Ser Asp Asp Ile Gly Val Phe Leu Ser Lys Arg Ile Lys Val
                 140                 145                 150

 Ile Ser Lys Pro Ser Lys Lys Lys Gln Ser Leu Lys Asn Ala Asp
                 155                 160                 165

 Leu Cys Ile Ala Ser Gly Thr Lys Val Ala Leu Phe Asn Arg Leu
                 170                 175                 180

 Arg Ser Gln Thr Val Ser Thr Arg Tyr Leu His Val Glu Gly Gly
                 185                 190                 195

 Asn Phe His Ala Ser Ser Gln Gln Trp Gly Ala Phe Phe Ile His
                 200                 205                 210

 Leu Leu Asp Asp Asp Glu Ser Glu Gly Glu Glu Phe Thr Val Arg
                 215                 220                 225

 Asp Gly Tyr Ile His Tyr Gly Gln Thr Val Lys Leu Val Cys Ser
                 230                 235                 240

 Val Thr Gly Met Ala Leu Pro Arg Leu Ile Ile Arg Lys Val Asp
                 245                 250                 255

 Lys Gln Thr Ala Leu Leu Asp Ala Asp Asp Pro Val Ser Gln Leu
                 260                 265                 270

 His Lys Cys Ala Phe Tyr Leu Lys Asp Thr Glu Arg Met Tyr Leu
                 275                 280                 285

 Cys Leu Ser Gln Glu Arg Ile Ile Gln Phe Gln Ala Thr Pro Cys
                 290                 295                 300

 Pro Lys Glu Pro Asn Lys Glu Met Ile Asn Asp Gly Ala Ser Trp
                 305                 310                 315

 Thr Ile Ile Ser Thr Asp Lys Ala Glu Tyr Thr Phe Tyr Glu Gly
                 320                 325                 330

 Met Gly Pro Val Leu Ala Pro Val Thr Pro Val Pro Val Val Glu
                 335                 340                 345

 Ser Leu Gln Leu Asn Gly Gly Gly Asp Val Ala Met Leu Glu Leu
                 350                 355                 360

 Thr Gly Gln Asn Phe Thr Pro Asn Leu Arg Val Trp Phe Gly Asp
                 365                 370                 375

 Val Glu Ala Glu Thr Met Tyr Arg Cys Gly Glu Ser Met Leu Cys
                 380                 385                 390

 Val Val Pro Asp Ile Ser Ala Phe Arg Glu Gly Trp Arg Trp Val
                 395                 400                 405

 Arg Gln Pro Val Gln Val Pro Val Thr Leu Val Arg Asn Asp Gly
                 410                 415                 420

 Ile Ile Tyr Ser Thr Ser Leu Thr Phe Thr Tyr Thr Pro Glu Pro
                 425                 430                 435

 Gly Pro Arg Pro His Cys Ser Ala Ala Gly Ala Ile Leu Arg Ala
                 440                 445                 450

 Asn Ser Ser Gln Val Pro Pro Asn Glu Ser Asn Thr Asn Ser Glu
                 455                 460                 465

 Gly Ser Tyr Thr Asn Ala Ser Thr Asn Ser Thr Ser Val Thr Ser
                 470                 475                 480

 Ser Thr Ala Thr Val Val Ser
                 485

<210> 2480
<211> 3718
<212> DNA
<213> Homo sapien

<400> 2480
 ggtggtggtg ctgggagtgt cgtggacgcc gtgccgttac tcgtagtcag 50

 gcggcggcgc aggcggcggc ggcggcatag cgcacagcgc gccttagcag 100

 cagcagcagc agcagcagca tcggaggtac ccccgccgtc gcagcccccg 150

 cgctggtgca gccaccctcg ctccctctgc tcttcctccc ttcgctcgca 200

 ccatggctga tcagctgacc gaagaacaga ttgctgaatt caaggaagcc 250

 ttctccctat ttgataaaga tggcgatggc accatcacaa caaaggaact 300

 tggaactgtc atgaggtcac tgggtcagaa cccaacagaa gctgaattgc 350

 aggatatgat caatgaagtg gatgctgatg gtaatggcac cattgacttc 400

 cccgaatttt tgactatgat ggctagaaaa atgaaagata cagatagtga 450

 agaagaaatc cgtgaggcat tccgagtctt tgacaaggat ggcaatggtt 500

 atatcagtgc agcagaacta cgtcacgtca tgacaaactt aggagaaaaa 550

 ctaacagatg aagaagtaga tgaaatgatc agagaagcag atattgatgg 600

 agacggacaa gtcaactatg aagaattcgt acagatgatg actgcaaaat 650

 gaagacctac tttcaactcc tttttccccc ctctagaaga atcaaattga 700

 atcttttact tacctcttgc aaaaaaaatg aaaaatgaaa aaaacaaatt 750

 caaaacctat tcaaatgggt tctagttcaa tttgtttagt ataaattgtc 800

 atagctggtt tactgaaaac aaacacattt aaaattggtt tacctcagga 850

 tgacgtgcag aaaaatgggt gaaggataaa ccgttgagac gtggccccac 900

 tggtaggatg gtcctcttgt acttcgtgtg ctccgaccca tggtgacgat 950

 gacacaccct ggtggcatgc ccgtgtatgt tggtttagcg ttgtctgcat 1000

 tgttctagag tgaaacaggt gtcaggctgt cactgttcac acaaattttt 1050

 aataagaaac atttaccaag ggagcatctt tggactctct gtttttaaaa 1100

 ccttctgaac catgacttgg agccggcaga gtaggctgtg gctgtggact 1150

 tcagcacaac catcaacatt gctgttcaaa gaaattacag tttacgtcca 1200

 ttccaagttg taaatgctag tctttttttt ttttttttcc aataaaaaga 1250

 ccattaactt aaagtggtgt taaatgcttt gtaaagctga gatctaaatg 1300

 gggacaaggc aggtggaggg gaggccagtg tacatgtaaa tgcccacagc 1350

 ccagcattgg gtttccctcc caaggcccca gcaccaacct ctgagcccaa 1400

 gaccttgcct gaaaacaagc agataccgat tgcttcatcc tatttatgga 1450

 catgtaggtc tagttgcatt ttcactgggg ggagggggga aggtgaatta 1500

 tggtaacttt taatgatcta ttcaggcagt agagctctta aggaaaaaaa 1550

 aaacccactt tctctcaagc atgtatttag gggttgttct caattgtgct 1600

 gctgattacc tgtcttatgt aactacttga gaccatctgc aagagacatg 1650

 atttagtgtg tctgtaattc aatcttcgct gtgtgtggta gaagcagtag 1700

 tcacttttgt aagccagtct cttcatgcct aaaagacact accagtcacc 1750

 tttgattcgc gacttttaat ttatgattat acttagcctc ctcctccttt 1800

 tttttttttt cccaagttga cttgactttg cttttttccc cccaagtaga 1850

 actaatgcta gcttccagct tgaaagtaaa actccagtgt ggagtgaatt 1900

 ttgtgtctaa ttataaacct gtaaccaaaa ctcagacatc tggtactggt 1950

 ctttgcattg agattggtcc ctgtaaaacc ccctttaaaa catattgcat 2000

 ttagtacaga gctctttttt gaaatgaagg ctggagatgt gcatttttca 2050

 cggtgttaac tggttgtatc ttattagcaa ggagattggg gttttgagtg 2100

 tttgcgtggg tggtttcaat ttgccaggga acagtggcag gctgctagca 2150

 aggcagtgag aagctcttgg cagccaaatg ggtgcattca gggctgattt 2200

 atagagaccc ttggcttctc cttctcctac tccctgtctt tctggcattt 2250

 tgtagcttgt tagattttct gccagagggg tgggtcagag cagtggaggg 2300

 gagacatcgc ccatgtgctt ctgctactgg tccttgggct gggtggttgg 2350

 tagaggagat gttgacacta tgagctaagg gttggctttt gtaattacct 2400

 gaatctgaaa ggaatgccta aggttacctt ggggtttctc ttctggtgag 2450

 atagggttcc tggtttgagt aagttaatgt cctggatatt tcttgtggca 2500

 gggggtggtc aaagagcctg attgctgacc cagtctcagg cctgtggtcg 2550

 atgacctctc ggtagtttca aagggggctg gagggggata tttgacttgt 2600

 tttttcgaaa tgtagccttc taaccctcaa gtctttagaa gctgggtgga 2650

 ctcttagtgg tcctgcagcg tatcctaaaa gactaccttt gaaacaggat 2700

 tcttgtatgg ccaggatcgt gtctgggaac cagaaaccct acaccctccc 2750

 cctccaggga atgctgagtt ccagttttga gcagaggtga ggcagaatcc 2800

 actgtagcct tccgccctgg tatttggggg gatgaccagc ccaggcgttg 2850

 ggtgttagtc tgcatgagtt tgtgagagga aataactggg tgtcctggca 2900

 gtgcccttga agttggttag gaccttcctg taaactcttg cccctacttc 2950

 taactactct ataaatatat acatatattt atatataaag tgattagttg 3000

 aactggcatc ctgctttagc ctgagacttg ccataagaaa ctgctgagta 3050

 cttggcaaac cctttcatag ttttgttctc catctgtttg gggtaggtgt 3100

 tgagcgaggc aaatggatct cgatatttca gatgggcttt tgatgcactg 3150

 ttgccaagga aggctttttc tgattttttg acaaatgaat ttttgcacac 3200

 tttcattggt gtctttcggc aacttacaca cattgaaaat gagctattgt 3250

 acatattttt atattctctt tataaatgca tgtctgattg tacttgtaac 3300

 aatattgtaa tgaacggctg tgcagtaggc ccagcgctgc tgtgtctcgt 3350

 cagaggaata gcttaccacg aacccctcag catactggga atctcttcct 3400

 gaacaacgaa tgtaaatttg gtcaagtcta ctcttccgtt cattcaatta 3450

 ttttaagcat ttgaattatt tattgtatat cctaaatata tttctccttt 3500

 ggcagtgact agatttccac taatgtgtct taatctatcc ctccagctgg 3550

 cagttactgt ttttttaatc ccctgaagtt gtcctgtagg agacagaaat 3600

 tctttgctgt ctgtatccct tggagtaaga aggtagtggc atgggtggag 3650

 tgtgtgttct ttctccaaat ctattatgat gtttattaaa cacttctgta 3700

 gcaaaaaaaa aaaaaaaa 3718

<210> 2481
<211> 149
<212> PRT
<213> Homo sapien

<400> 2481
 Met Ala Asp Gln Leu Thr Glu Glu Gln Ile Ala Glu Phe Lys Glu
   1               5                  10                  15

 Ala Phe Ser Leu Phe Asp Lys Asp Gly Asp Gly Thr Ile Thr Thr
                  20                  25                  30

 Lys Glu Leu Gly Thr Val Met Arg Ser Leu Gly Gln Asn Pro Thr
                  35                  40                  45

 Glu Ala Glu Leu Gln Asp Met Ile Asn Glu Val Asp Ala Asp Gly
                  50                  55                  60

 Asn Gly Thr Ile Asp Phe Pro Glu Phe Leu Thr Met Met Ala Arg
                  65                  70                  75

 Lys Met Lys Asp Thr Asp Ser Glu Glu Glu Ile Arg Glu Ala Phe
                  80                  85                  90

 Arg Val Phe Asp Lys Asp Gly Asn Gly Tyr Ile Ser Ala Ala Glu
                  95                 100                 105

 Leu Arg His Val Met Thr Asn Leu Gly Glu Lys Leu Thr Asp Glu
                 110                 115                 120

 Glu Val Asp Glu Met Ile Arg Glu Ala Asp Ile Asp Gly Asp Gly
                 125                 130                 135

 Gln Val Asn Tyr Glu Glu Phe Val Gln Met Met Thr Ala Lys
                 140                 145

<210> 2482
<211> 3952
<212> DNA
<213> Homo sapien

<400> 2482
 gcatgtattt agtaggttag aggtgggaac tagagatcag agaattgttt 50

 atggcagcag agttagcagt aacttgagag ggcatagcta agtcaaagac 100

 ctacttcccc acactacatc attagcaata acaattgctg aatgttcaca 150

 ggatggcaat ggttatatca gtgcagcaga actacgtcac gtcatgacaa 200

 acttaggaga aaaactaaca gatgaagaag tagatgaaat gatcagagaa 250

 gcagatattg atggagacgg acaagtcaac tatgaagaat tcgtacagat 300

 gatgactgca aaatgaagac ctactttcaa ctcctttttc ccccctctag 350

 aagaatcaaa ttgaatcttt tacttacctc ttgcaaaaaa aagaaaaaag 400

 aaaaaagttc atttattcat tctgtttcta tatagcaaaa ctgaatgtca 450

 aaagtacctt ctgtccacac acacaaaatc tgcatgtatt ggttggtggt 500

 cctgtcccct aaagatcaag ctacacatca gttttacaat ataaatactt 550

 gtactacctt aatgataagg actccttaaa gttccatttg ctaatgatta 600

 atacactgtt tgggctggcc agtttttcat gcatgcagct tgacgattga 650

 gcacagtcag gcctttgtat taaaaatgaa aaatgaaaaa acaaattcaa 700

 aacctattca aatgggttct agttcaattt gtctagtata aattgtcata 750

 gctggtttac tgaaaacaaa cacatttaaa atgggtttac ctcaggatga 800

 cgtgcagaaa aatgggtgaa ggataaaccg ttgagacgtg gccccactgg 850

 taggatggtc ctcttgtact tcgtgtgctc cgaaccatgg tgacgatgac 900

 acaccctggg ggcatgcccg tgtatgttgg tttagcgttg tctgcattgt 950

 tctagagtga aacaggtgtc aggctgtcac tgttcacaca aatttttaat 1000

 aagaaacatt taccaaggga gcatctttgg actctctgtt tttaaaacct 1050

 tctgaaccat gacttggagc cggcagagta ggctgtggct gtggacttca 1100

 gcacaaccat caacattgct gttcaaagaa attacagttt acgtccattc 1150

 caagttgtaa atgctagtct ttttcttttt tttttccaat aaaaagacca 1200

 ttaacttaaa gtggtgttaa atgctttgta aagctgagat ctaaatgggg 1250

 acaaggcagg tggaggggag gccagtgtac atgtaaatgc ccacagccca 1300

 gcattgggtt tccctcccaa ggccccagca ccaacctctg agcccaagac 1350

 cttgcctgaa aacaagcaga taccgattgc ttcatcctat ttatggacat 1400

 gtaggtctag ttgcattttc actgggggga ggggggaagg tgaattatgg 1450

 taacttttaa tgatctattc aggcagtaga gctcttaagg aaaaaaaaaa 1500

 acccactttc tctcaagcat gtatttaggg gttgttctca attgtgctgc 1550

 tgattacctg tcttatgtaa ctacttgaga ccatctgcaa gagacatgat 1600

 ttagtgtgtc tgtaattcaa tcttcgctgt gtgtggtaga agcagtagtc 1650

 acttttgtaa gccagtctct tcatgcctaa aagacactac cagtcacctt 1700

 tgattcgcga cttttaattt atgattatac ttagcctcct cctccttttt 1750

 ttttttttcc caagttgact tgactttgct tttttccccc caagtagaac 1800

 taatgctagc ttccagcttg aaagtaaaac tccagtgtgg agtgaatttt 1850

 gtgtctaatt ataaacctgt aaccaaaact cagacatctg gtactggtct 1900

 ttgcattgag attggtccct gtaaaacccc ctttaaaagc atattgcatt 1950

 tagtacagag ctcttttttg aaatgaaggc tggagatgtg catttttcac 2000

 ggtgttaact ggttgtatct tattagcaag gagattgggg ttttgagtgt 2050

 ttgcgtgggt ggtttcaatt tgccagggaa cagtggcagg ctgctagcaa 2100

 ggcagtgaga agctcttggc agccaaatgg gtgcattcag ggctgattta 2150

 tagagaccct tggcttctcc ttctcctact ccctgtcttt ctggcatttt 2200

 gtagcttgtt agattttctg ccagaggggt gggtcagagc agtggagggg 2250

 agacatcgcc catgtgcttc tgctactggt ccttgggctg ggtggttggt 2300

 agaggagatg ttgacactat gagctaaggg ttggcttttg taattacctg 2350

 aatctgaaag gaatgcctaa ggttaccttg gggtttctct tctggtgaga 2400

 tagggttcct ggtttgagta agttaatgtc ctggatattt cttgtggcag 2450

 ggggtggtca aagagcctga ttgctgaccc agtctcaggc ctgtggtcga 2500

 tgacctctcg gtagtttcaa agggggctgg agggggatat ttgacttgtt 2550

 ttttcgaaat gtagccttct aaccctcaag tctttagaag ctgggtggac 2600

 tcttagtggt cctgcagcgt atcctaaaag actacctttg aaacaggatt 2650

 cttgtatggc caggatcctg tctgggaacc agaaacccta caccctcccc 2700

 ctccagggaa tgctgagttc cagttttgag cagaggtgag gcagaatcca 2750

 ctgtagcctt ccgccctggt atttgggggg atgaccagcc caggcgttgg 2800

 gtgttagtct gcatgagttt gtgagaggaa atagctgggt gtcctggcag 2850

 tgcccttgaa gttggttagg accttcctgt aaactcttgc ccctacttct 2900

 aactactcta taaatatata catatattta tatataaagt gattagttga 2950

 actggcatcc tgctttagcc tgagacttgc cataagaaac tgctgagtac 3000

 ttggcaaacc ctttcatagt tttgttctcc atctgtttgg ggtaggtgtt 3050

 gagcgaggca aatggatctc gatatttcag atgggctttt gatgcactgt 3100

 tgccaaggaa ggctttttct gattttttga caaatgaatt tttgcacact 3150

 ttcattggtg tctttcggca acttacacac attgaaaatg agctattgta 3200

 catattttta tattctcttt ataaatgcat gtctgattgt acttgtaaca 3250

 atattgtaat gaacggctgt gcagtaggcc cagcgctgct gtgtctcgtc 3300

 agaggaatag cttaccacga acccctcagc atactgggaa tctcttcctg 3350

 aacaacgaat gtaaatttgg tcaagtctac tcttccgttc attcaattat 3400

 tttaagcatt tgaattattt attgtatatc ctaaatatat ttctcctttg 3450

 gcagtgacta gatttccact aatgtgtctt aatctatccc tccagctggc 3500

 agttactgtt tttttaatcc cctgaagttg tcctgtagga gacagaaatt 3550

 ctttgctgtc tgtatccctt ggagtaagaa ggtagtggca tgggtggagt 3600

 gtgtgttctt tctccaaatc tattatgatg tttattaaac acttctgtag 3650

 caaagatggt ggtagttctt ttgttactga agttgccctt caccatggct 3700

 atttgaaaag gagatgtact tggacgtttc tgtaaatctt gagataaact 3750

 gtttggagat ttaaccacct ctctgatggg ggaccaactc tatggaaatt 3800

 gtaaatacgt tttatttata aacctggcac tgtattcaat aaacatttct 3850

 gcagcctttc atctcccaaa aaaatctatg tcgggtgcgg agaaagaggt 3900

 aatgaaatgg caggaattcg atatcagcta tcataccgtc acctcgaggg 3950

 gc 3952

<210> 2483
<211> 58
<212> PRT
<213> Homo sapien

<400> 2483
 Met Gly Asp Gln Leu Tyr Gly Asn Cys Lys Tyr Val Leu Phe Ile
   1               5                  10                  15

 Asn Leu Ala Leu Tyr Ser Ile Asn Ile Ser Ala Ala Phe His Leu
                  20                  25                  30

 Pro Lys Lys Ser Met Ser Gly Ala Glu Lys Glu Val Met Lys Trp
                  35                  40                  45

 Gln Glu Phe Asp Ile Ser Tyr His Thr Val Thr Ser Arg
                  50                  55

<210> 2484
<211> 7709
<212> DNA
<213> Homo sapien

<400> 2484
 cgaaggacct gaaggaaagt ggaaaagtcc aaagtttaag atgccagaga 50

 tgcattttaa gactccaaag atatccatgc cagatattga cctgaatctc 100

 acaggtccaa aaataaaagg agatgtggat gttacaggcc ctaaggtaga 150

 gggagatctg aaaggtcctg aagttgacct caaaggcccc aaagtggaca 200

 ttgatgtccc agatgttaat gttcagggtc cagactggca cctgaagatg 250

 cccaagatga aaatgcctaa gttcagtatg cctggcttca aaggagaggg 300

 cccagatggt ggatgtgaag ctgcccatag gctgacattg atgtctcagg 350

 accaaagtgg acattgaagg ccctgatgtt aacattgaag gaccagaggg 400

 aaagttgaaa gggcctaagt tcaagatgcc agagatgaat atcaaagccc 450

 ccaagatctc catgcctgat attgacttaa acctgaaagg acccaagtga 500

 agggtgatgt ggatgtttcc cttcctaaag tggaaggtga cctcaagggc 550

 ccagaagttg acatcaaggg cccaaaagtg gacattgacg cacctgatgt 600

 tgatgttcat ggcccagact ggcacctaaa gatgcccaag atgaaaatgc 650

 ccaagttcag catgcctggc ttcaaagcag agggccctga agctggaatg 700

 tgaacctgcc caaggctgac gttgatgtct caggccccaa agtggatatt 750

 aatgccccag atgtgggtgt tcaaggccca gactggcacc tgaagatgcc 800

 caaggtgaaa atgccaaagt tcagcatgcc tggcttcaaa ggagagggcc 850

 cagatgggga tgtgaagctg cccaaggctg acattgatgt ctcaggaccc 900

 aaagtggaca ttgaaggccc tgatgttaac attgaaggac cagagggaaa 950

 gttgaaaggg cctaagttca agatgccaga gatgaatatc aaagccccca 1000

 agatctccat gcctgatatt gacttaaacc tgaaaggacc caaagtgaag 1050

 ggtgatgtgg atgtttccct tcctaaagtg gaaggtgacc tcaagggccc 1100

 agaagttgac atcaagggcc caaaagtgga cattgacgca cctgatgttg 1150

 atgttcatgg cccagactgg cacctaaaga tgcccaagat aaaaatgccc 1200

 aagatcagca tgcctggctt caaaggagaa ggtccagatg tggacgtgaa 1250

 cctgcccaag gctgacattg atgtctcagg accgaaagtg gatgttgaat 1300

 gtcccgatgt gaatatcgaa ggacctgaag gaaagtggaa aagtccaaag 1350

 tttaagatgc cagagatgca ttttaagact ccaaagatat ccatgccaga 1400

 tattgacctg aatctcacag gtccaaaaat aaaaggagat gtggatgtta 1450

 caggccctaa ggtagaggga gatctgaaag gtcctgaagt tgacctcaaa 1500

 ggccccaaag tggacattga tgtcccagat gttaatgttc agggtccaga 1550

 ctggcacctg aagatgccca agatgaaaat gcccaagttc agcatgcctg 1600

 gcttcaaagc agagggccct gaagtggatg tgaacctgcc caaggctgac 1650

 gttgatgtct caggccccaa agtggacgtt gaaggccctg atgttaacat 1700

 tgaaggacca gagggaaagt tgaaagggcc caagttcaag atgccagaga 1750

 tgaatatcaa agcccccaag atccccatgc ctgactttga tttgcatctg 1800

 aaaggtccca aggtgaaggg cgatgtggat atttctctgc ccaaagtgga 1850

 aggtgacctc aagggccctg aagttgacat caggggtccc aaagtggaca 1900

 ttgatgtccc ggatgtgggc gttcaaggcc cagactggca cctaaaaatg 1950

 cccaaagtga aaatgcccaa attcagcatg cctggcttca aaggagaggg 2000

 cccagatgtg gatgtgaacc tgcccaaggc tgaccttgat gtctcaggac 2050

 ccaaggtgga cattgatgtt ccagatgtga atatcgaagg cccagaggga 2100

 aagttgaaag gtcccaaatt caaaatgcct gagatgaaca tcaaagcccc 2150

 caagatctcc atgcctgaca ttgatcttaa cctgaaaggt cccaaagtga 2200

 agggtgacat ggatgtgtct ctgccaaaag tggaaggtga catgaaagtt 2250

 cctgacgtgg atattaaagg ccccaaagtg gatattaatg ccccagatgt 2300

 ggatgttcaa ggcccagact ggcacctgaa gatgcctaaa ataaaaatgc 2350

 ccaagatcag catgcctggc ttcaaaggag aaggtccaga agtggacgtg 2400

 aacctgccca aggctgacct tgacgtctca ggacccaagg tggacgttga 2450

 tgttccagat gtgaatattg aaggtccaga tgcgaaactg aagggcccta 2500

 aattcaagat gccagagatg aacatcaaag cccccaagat ctccatgcct 2550

 gactttgatt tgcatctgaa aggccctaag gtgaaaggag atgtggatgt 2600

 ttctctgcct aagatggaag gtgatctaaa gggtcctgaa gttgacatca 2650

 agggccccaa agtggacatt aatgctccag atgtggatgt tcaaggccca 2700

 gactggcacc tgaagatgcc caaggtgaaa atgcccaagt tcagcatgcc 2750

 tggcttcaaa ggagagggcc cagatgtgga tgtgaacctg cccaaggctg 2800

 accttgatgt ctcaggaccc aaggtggaca ttgatgttcc tgatgtggat 2850

 atccgaaggt ccagaaggga aactgaaagg tcccaaattc aagatgcctg 2900

 agatgagcat ccaagccccc aagatctcca tgcctgatat tgacttaaac 2950

 ctgaaaggac ccaaagtgaa gggcgatgtg gatgttaccc ttcctaaagt 3000

 ggaaggtgac ctcaagggcc cagaagctga catcaagggc ccaaaagtgg 3050

 acatcaacac ccctgatgtg gatgttcatg gcccagactg gcacctgaag 3100

 atgcccaagg tgaaaatgcc caaattcagc atgcctggct tcaaaggaga 3150

 aggtccagat gtggatgtga acctgcccaa ggctgacatt gatgtctcag 3200

 gacccaaagt ggacgttgat gttcctgatg tgaatatcga aggtccagat 3250

 gcgaaactaa agggccccaa gttcaagatg cctgagatga gcatcaaagc 3300

 ccccaagatc tccatgcctg atattgactt aaacctgaaa ggacccaaag 3350

 tgaagggcga tgtggatgtt acccttccta aagtggaagg tgacctcaag 3400

 ggcccagaag ctgacatcaa gggcccaaaa gtggacatca acacccctga 3450

 tgtggatgtt catggcccag actggcacct gaagatgccc aaggtgaaaa 3500

 tgcccaaatt cagcatgcct ggcttcaaag gagaaggtcc agatgtggat 3550

 gtgagcctgc ccaaggccga catcgatgtc tcgggaccca aggtggacgt 3600

 tgatattcca gatgtgaata tcgaaggtcc agacgcaaaa ctgaagggcc 3650

 ccaagttcaa gatgcctgaa ataaatatca aagctcccaa gatctccata 3700

 cctgatgttg acctggattt gaaaggaccc aaagtaaaag gagattttga 3750

 tgtgtctgtc cctaaggttg aagggacttt gaaaggccca gaagtagatc 3800

 ttaaaggtcc acgtctggat ttcgaaggcc ctgatgccaa actcagtggc 3850

 ccatctttga agatgccatc gctggagata tctgctccta aagtaactgc 3900

 tcctgatgtt gatttgcatc tcaaggcacc aaaaattgga ttttcaggtc 3950

 cgaagttaga aggtggtgaa gtggacctca agggacccaa agttgaagct 4000

 ccaagcttag atgtacacat ggacagccca gatattaaca tcgaagggcc 4050

 agatgttaaa atccccaaat ttaagaaacc caagtttgga tttggggcaa 4100

 aaagccccaa agctgacatc aagtcacctt cactggatgt cactgttcct 4150

 gaggcagagc tgaaccttga gactcctgaa attagtgttg gtggcaaggg 4200

 caagaaaagt aagtttaaaa tgcctaaaat tcatatgagt ggtcctaaga 4250

 ttaaggccaa aaaaacaggg atttgacctg aatgttcctg ggggtgaaat 4300

 tgatgccagc ctcaaggctc cggatgtaga tgtcaacatc gcagggccgg 4350

 atgctgcact caaagtcgac gtgaaatcgc ccaaaaccaa gaaaacgatg 4400

 tttggaaaaa tgtacttccc agatgtagag tttgacatta aatcacctaa 4450

 atttaaagct gaggcccctc tccctagccc caaactggag ggtgaactcc 4500

 aggcacctga tctggaactt tctttgccag cgattcacgt cgaaggtctt 4550

 gacatcaagg cgaaggctcc caaggtcaag atgccagatg tggacatctc 4600

 agtgccaaaa atagagggtg acctgaaagg ccccaaagtg caggcaaact 4650

 tgggtgcacc tgacatcaac atcgaaggcc tagatgctaa agtcaaaaca 4700

 ccgtccttcg gcatttctgc ccctcaagtc tccatccctg atgtgaatgt 4750

 aaacttgaaa ggaccaaaga taaagggtga tgtccccagc gtgggactgg 4800

 aaggaccaga tgtagatctg caaggtccag aagcaaaaat taagttcccc 4850

 aagttttcca tgcccaagat cggcatccca ggtgtgaaaa tggagggtgg 4900

 gggagccgag gtccatgccc agctaccctc tcttgaagga gacttgagag 4950

 gaccagatgt taagctcgaa gggcccgatg tttctctaaa ggggccagga 5000

 gtagacttgc cttcagtgaa cctctctatg ccaaaagtct ctgggcctga 5050

 ccttgatctg aacttgaaag gaccaagttt gaagggagac ctggatgcat 5100

 ctgttcccag catgaaggtg catgctccag ggctcaacct cagtggtgtc 5150

 ggtggcaaaa tgcaggtggg aggagacggt gtgaaagtgc cagggatcga 5200

 tgccacaaca aagcttaacg ttggggcacc agatgtgaca ctgaggggac 5250

 caagcctgca gggagatctg gctgtctctg gtgacatcaa atgccctaaa 5300

 gtatccgtag gagctcctga tctaagcttg gaggcatccg aaggcagcat 5350

 taaacttccc aaaatgaagc tgccccaatt tggcatctct actccggggt 5400

 ccgacttgca cgtcaatgcc aaggggccac aggtttctgg cgaactgaag 5450

 gggccaggtg tggatgtgaa cctgaaaggg cctcggattt cagcaccgaa 5500

 tgtggacttt aacttggaag gaccaaaagt gaaagggagc cttggggcca 5550

 ctggtgagat caaaggcccc actgtcggag gaggtcttcc aggcattggt 5600

 gttcaaggcc tagaaggaaa cctccagatg cctggaatta agtcctctgg 5650

 atgtgatgtg aacctgccag gcgtgaatgt gaaactccca actgggcaga 5700

 tttctgggcc tgaaatcaaa ggtggtctga aaggttcaga agtaggtttc 5750

 catggggctg ctcctgatat cagtgtgaag gggcctgcct ttaatatggc 5800

 atctcctgag tcagattttg gcatcaactt gaagggccca aaaatcaaag 5850

 gaggtgcgga tgtttcaggg ggtgtcagtg ccccagacat cagccttggt 5900

 gaagggcatt tgagtgttaa aggttccggg ggtgagtgga agggacccca 5950

 agtctcctct gctctcaact tggacacatc taagtttgct gggggccttc 6000

 atttctcagg accaaaggtg gaaggaggtg tgaaaggagg tcagattgga 6050

 ctccaggctc ctgggctgag tgtgtctggg cctcaaggtc acttggaaag 6100

 tggatctgga aaagtaacat tccctaaaat gaagatcccc aaatttacct 6150

 tctctggccg tgagctggtt ggcagagaaa tgggggtgga tgttcacttc 6200

 cctaaagcag aggccagcat ccaagctggt gctggagacg gcgagtggga 6250

 agagtctgaa gtcaaactga aaaagtccaa gatcaaaatg cccaagttta 6300

 atttttccaa acctaaaggg aaaggtggtg tcactggctc accagaagca 6350

 tcaatttctg ggtccaaagg tgacctgaaa agttcaaagg ccagcctggg 6400

 ctctctggaa ggagaggcag aggccgaagc ctcttcaccg aaaggcaaat 6450

 tctccttatt taaaagtaag aagccacggc accgctcaaa ttcattcagt 6500

 gatgaaagag agttctctgg accttccacc ccgacgggga cgctggagtt 6550

 tgaaggtggg gaagtgtctc tggaaggtgg gaaagttaaa gggaaacacg 6600

 ggaagctgaa attcggtacc tttggtggat tggggtcaaa gagcaaaggt 6650

 cattatgagg tgactgggag cgatgatgag acaggcaagt tacaggggag 6700

 tggggtgtcc ctggcctcta agaagtcccg actgtcctcc tcttctagca 6750

 atgacagtgg gaataaggtt ggcatccagc ttcccgaggt ggagctgtca 6800

 gtttccacaa agaaagagta gcaggccttt gtatgtgtgt acatatatat 6850

 atatataaca aaacatcagc cttgggtggt gtgttcctat ataaactcca 6900

 aagggaaaca caccgactgc ctcagcaatc atgcaaagac cttgcctggc 6950

 ccggtggcaa gcgctgaaaa accgaccgcc tgtaggctcc tggaactata 7000

 cagataggta aagagttcca agttcgtcca gcccatgtgc aaagtcaaca 7050

 gtatttgcct taagatttca tatatatata tttttttgca ttgactgctg 7100

 agagctcctg tttactaagc aagcttttgt gtttattatc ctcattttta 7150

 ctgaacattg ttagttttgg ggtaatggaa acccactttt tcattgtaat 7200

 gactttgggg gcttttgtta gtaagggtgg gtggggtgat gggttgcaga 7250

 cggaggtcag gtcttcctct ttcctgagac tggatctgtt caaacagcaa 7300

 acgcccacag atggcccaga ggtggtggta gtcagggtgt gtgggtgttt 7350

 ttagggttct ttagtgttgt ttctttcacc caggggtggt ggtcccagcc 7400

 agtttggtgc tgacggtgag aggaaattag aatctgtttg caaattgtcc 7450

 aacccacccc ctcaacatga ggggcttcca ttttctgtgt tttgtaaggg 7500

 aactgtttcc ttcatgccgc catgttcctg atattagttc tgatttcttt 7550

 ttaacaaatg ttatcatgat taagaaaatt tccagcactt taatggccaa 7600

 ttaactgaga atgtaagaaa attgatgctg tacaaggcaa ataaagctgt 7650

 ttattaacct ccgaaaaaaa atctatgtcg ggtgcggaga aagaggtaat 7700

 gaaatggca 7709

<210> 2485
<211> 2007
<212> PRT
<213> Homo sapien

<400> 2485
 Met Pro Lys Val Lys Met Pro Lys Phe Ser Met Pro Gly Phe Lys
   1               5                  10                  15

 Gly Glu Gly Pro Asp Gly Asp Val Lys Leu Pro Lys Ala Asp Ile
                  20                  25                  30

 Asp Val Ser Gly Pro Lys Val Asp Ile Glu Gly Pro Asp Val Asn
                  35                  40                  45

 Ile Glu Gly Pro Glu Gly Lys Leu Lys Gly Pro Lys Phe Lys Met
                  50                  55                  60

 Pro Glu Met Asn Ile Lys Ala Pro Lys Ile Ser Met Pro Asp Ile
                  65                  70                  75

 Asp Leu Asn Leu Lys Gly Pro Lys Val Lys Gly Asp Val Asp Val
                  80                  85                  90

 Ser Leu Pro Lys Val Glu Gly Asp Leu Lys Gly Pro Glu Val Asp
                  95                 100                 105

 Ile Lys Gly Pro Lys Val Asp Ile Asp Ala Pro Asp Val Asp Val
                 110                 115                 120

 His Gly Pro Asp Trp His Leu Lys Met Pro Lys Ile Lys Met Pro
                 125                 130                 135

 Lys Ile Ser Met Pro Gly Phe Lys Gly Glu Gly Pro Asp Val Asp
                 140                 145                 150

 Val Asn Leu Pro Lys Ala Asp Ile Asp Val Ser Gly Pro Lys Val
                 155                 160                 165

 Asp Val Glu Cys Pro Asp Val Asn Ile Glu Gly Pro Glu Gly Lys
                 170                 175                 180

 Trp Lys Ser Pro Lys Phe Lys Met Pro Glu Met His Phe Lys Thr
                 185                 190                 195

 Pro Lys Ile Ser Met Pro Asp Ile Asp Leu Asn Leu Thr Gly Pro
                 200                 205                 210

 Lys Ile Lys Gly Asp Val Asp Val Thr Gly Pro Lys Val Glu Gly
                 215                 220                 225

 Asp Leu Lys Gly Pro Glu Val Asp Leu Lys Gly Pro Lys Val Asp
                 230                 235                 240

 Ile Asp Val Pro Asp Val Asn Val Gln Gly Pro Asp Trp His Leu
                 245                 250                 255

 Lys Met Pro Lys Met Lys Met Pro Lys Phe Ser Met Pro Gly Phe
                 260                 265                 270

 Lys Ala Glu Gly Pro Glu Val Asp Val Asn Leu Pro Lys Ala Asp
                 275                 280                 285

 Val Asp Val Ser Gly Pro Lys Val Asp Val Glu Gly Pro Asp Val
                 290                 295                 300

 Asn Ile Glu Gly Pro Glu Gly Lys Leu Lys Gly Pro Lys Phe Lys
                 305                 310                 315

 Met Pro Glu Met Asn Ile Lys Ala Pro Lys Ile Pro Met Pro Asp
                 320                 325                 330

 Phe Asp Leu His Leu Lys Gly Pro Lys Val Lys Gly Asp Val Asp
                 335                 340                 345

 Ile Ser Leu Pro Lys Val Glu Gly Asp Leu Lys Gly Pro Glu Val
                 350                 355                 360

 Asp Ile Arg Gly Pro Lys Val Asp Ile Asp Val Pro Asp Val Gly
                 365                 370                 375

 Val Gln Gly Pro Asp Trp His Leu Lys Met Pro Lys Val Lys Met
                 380                 385                 390

 Pro Lys Phe Ser Met Pro Gly Phe Lys Gly Glu Gly Pro Asp Val
                 395                 400                 405

 Asp Val Asn Leu Pro Lys Ala Asp Leu Asp Val Ser Gly Pro Lys
                 410                 415                 420

 Val Asp Ile Asp Val Pro Asp Val Asn Ile Glu Gly Pro Glu Gly
                 425                 430                 435

 Lys Leu Lys Gly Pro Lys Phe Lys Met Pro Glu Met Asn Ile Lys
                 440                 445                 450

 Ala Pro Lys Ile Ser Met Pro Asp Ile Asp Leu Asn Leu Lys Gly
                 455                 460                 465

 Pro Lys Val Lys Gly Asp Met Asp Val Ser Leu Pro Lys Val Glu
                 470                 475                 480

 Gly Asp Met Lys Val Pro Asp Val Asp Ile Lys Gly Pro Lys Val
                 485                 490                 495

 Asp Ile Asn Ala Pro Asp Val Asp Val Gln Gly Pro Asp Trp His
                 500                 505                 510

 Leu Lys Met Pro Lys Ile Lys Met Pro Lys Ile Ser Met Pro Gly
                 515                 520                 525

 Phe Lys Gly Glu Gly Pro Glu Val Asp Val Asn Leu Pro Lys Ala
                 530                 535                 540

 Asp Leu Asp Val Ser Gly Pro Lys Val Asp Val Asp Val Pro Asp
                 545                 550                 555

 Val Asn Ile Glu Gly Pro Asp Ala Lys Leu Lys Gly Pro Lys Phe
                 560                 565                 570

 Lys Met Pro Glu Met Asn Ile Lys Ala Pro Lys Ile Ser Met Pro
                 575                 580                 585

 Asp Phe Asp Leu His Leu Lys Gly Pro Lys Val Lys Gly Asp Val
                 590                 595                 600

 Asp Val Ser Leu Pro Lys Met Glu Gly Asp Leu Lys Gly Pro Glu
                 605                 610                 615

 Val Asp Ile Lys Gly Pro Lys Val Asp Ile Asn Ala Pro Asp Val
                 620                 625                 630

 Asp Val Gln Gly Pro Asp Trp His Leu Lys Met Pro Lys Val Lys
                 635                 640                 645

 Met Pro Lys Phe Ser Met Pro Gly Phe Lys Gly Glu Gly Pro Asp
                 650                 655                 660

 Val Asp Val Asn Leu Pro Lys Ala Asp Leu Asp Val Ser Gly Pro
                 665                 670                 675

 Lys Val Asp Ile Asp Val Pro Asp Val Asp Ile Arg Arg Ser Arg
                 680                 685                 690

 Arg Glu Thr Glu Arg Ser Gln Ile Gln Asp Ala Glu Met Ser Ile
                 695                 700                 705

 Gln Ala Pro Lys Ile Ser Met Pro Asp Ile Asp Leu Asn Leu Lys
                 710                 715                 720

 Gly Pro Lys Val Lys Gly Asp Val Asp Val Thr Leu Pro Lys Val
                 725                 730                 735

 Glu Gly Asp Leu Lys Gly Pro Glu Ala Asp Ile Lys Gly Pro Lys
                 740                 745                 750

 Val Asp Ile Asn Thr Pro Asp Val Asp Val His Gly Pro Asp Trp
                 755                 760                 765

 His Leu Lys Met Pro Lys Val Lys Met Pro Lys Phe Ser Met Pro
                 770                 775                 780

 Gly Phe Lys Gly Glu Gly Pro Asp Val Asp Val Asn Leu Pro Lys
                 785                 790                 795

 Ala Asp Ile Asp Val Ser Gly Pro Lys Val Asp Val Asp Val Pro
                 800                 805                 810

 Asp Val Asn Ile Glu Gly Pro Asp Ala Lys Leu Lys Gly Pro Lys
                 815                 820                 825

 Phe Lys Met Pro Glu Met Ser Ile Lys Ala Pro Lys Ile Ser Met
                 830                 835                 840

 Pro Asp Ile Asp Leu Asn Leu Lys Gly Pro Lys Val Lys Gly Asp
                 845                 850                 855

 Val Asp Val Thr Leu Pro Lys Val Glu Gly Asp Leu Lys Gly Pro
                 860                 865                 870

 Glu Ala Asp Ile Lys Gly Pro Lys Val Asp Ile Asn Thr Pro Asp
                 875                 880                 885

 Val Asp Val His Gly Pro Asp Trp His Leu Lys Met Pro Lys Val
                 890                 895                 900

 Lys Met Pro Lys Phe Ser Met Pro Gly Phe Lys Gly Glu Gly Pro
                 905                 910                 915

 Asp Val Asp Val Ser Leu Pro Lys Ala Asp Ile Asp Val Ser Gly
                 920                 925                 930

 Pro Lys Val Asp Val Asp Ile Pro Asp Val Asn Ile Glu Gly Pro
                 935                 940                 945

 Asp Ala Lys Leu Lys Gly Pro Lys Phe Lys Met Pro Glu Ile Asn
                 950                 955                 960

 Ile Lys Ala Pro Lys Ile Ser Ile Pro Asp Val Asp Leu Asp Leu
                 965                 970                 975

 Lys Gly Pro Lys Val Lys Gly Asp Phe Asp Val Ser Val Pro Lys
                 980                 985                 990

 Val Glu Gly Thr Leu Lys Gly Pro Glu Val Asp Leu Lys Gly Pro
                 995                1000                1005

 Arg Leu Asp Phe Glu Gly Pro Asp Ala Lys Leu Ser Gly Pro Ser
                1010                1015                1020

 Leu Lys Met Pro Ser Leu Glu Ile Ser Ala Pro Lys Val Thr Ala
                1025                1030                1035

 Pro Asp Val Asp Leu His Leu Lys Ala Pro Lys Ile Gly Phe Ser
                1040                1045                1050

 Gly Pro Lys Leu Glu Gly Gly Glu Val Asp Leu Lys Gly Pro Lys
                1055                1060                1065

 Val Glu Ala Pro Ser Leu Asp Val His Met Asp Ser Pro Asp Ile
                1070                1075                1080

 Asn Ile Glu Gly Pro Asp Val Lys Ile Pro Lys Phe Lys Lys Pro
                1085                1090                1095

 Lys Phe Gly Phe Gly Ala Lys Ser Pro Lys Ala Asp Ile Lys Ser
                1100                1105                1110

 Pro Ser Leu Asp Val Thr Val Pro Glu Ala Glu Leu Asn Leu Glu
                1115                1120                1125

 Thr Pro Glu Ile Ser Val Gly Gly Lys Gly Lys Lys Ser Lys Phe
                1130                1135                1140

 Lys Met Pro Lys Ile His Met Ser Gly Pro Lys Ile Lys Ala Lys
                1145                1150                1155

 Lys Thr Gly Ile Asp Leu Asn Val Pro Gly Gly Glu Ile Asp Ala
                1160                1165                1170

 Ser Leu Lys Ala Pro Asp Val Asp Val Asn Ile Ala Gly Pro Asp
                1175                1180                1185

 Ala Ala Leu Lys Val Asp Val Lys Ser Pro Lys Thr Lys Lys Thr
                1190                1195                1200

 Met Phe Gly Lys Met Tyr Phe Pro Asp Val Glu Phe Asp Ile Lys
                1205                1210                1215

 Ser Pro Lys Phe Lys Ala Glu Ala Pro Leu Pro Ser Pro Lys Leu
                1220                1225                1230

 Glu Gly Glu Leu Gln Ala Pro Asp Leu Glu Leu Ser Leu Pro Ala
                1235                1240                1245

 Ile His Val Glu Gly Leu Asp Ile Lys Ala Lys Ala Pro Lys Val
                1250                1255                1260

 Lys Met Pro Asp Val Asp Ile Ser Val Pro Lys Ile Glu Gly Asp
                1265                1270                1275

 Leu Lys Gly Pro Lys Val Gln Ala Asn Leu Gly Ala Pro Asp Ile
                1280                1285                1290

 Asn Ile Glu Gly Leu Asp Ala Lys Val Lys Thr Pro Ser Phe Gly
                1295                1300                1305

 Ile Ser Ala Pro Gln Val Ser Ile Pro Asp Val Asn Val Asn Leu
                1310                1315                1320

 Lys Gly Pro Lys Ile Lys Gly Asp Val Pro Ser Val Gly Leu Glu
                1325                1330                1335

 Gly Pro Asp Val Asp Leu Gln Gly Pro Glu Ala Lys Ile Lys Phe
                1340                1345                1350

 Pro Lys Phe Ser Met Pro Lys Ile Gly Ile Pro Gly Val Lys Met
                1355                1360                1365

 Glu Gly Gly Gly Ala Glu Val His Ala Gln Leu Pro Ser Leu Glu
                1370                1375                1380

 Gly Asp Leu Arg Gly Pro Asp Val Lys Leu Glu Gly Pro Asp Val
                1385                1390                1395

 Ser Leu Lys Gly Pro Gly Val Asp Leu Pro Ser Val Asn Leu Ser
                1400                1405                1410

 Met Pro Lys Val Ser Gly Pro Asp Leu Asp Leu Asn Leu Lys Gly
                1415                1420                1425

 Pro Ser Leu Lys Gly Asp Leu Asp Ala Ser Val Pro Ser Met Lys
                1430                1435                1440

 Val His Ala Pro Gly Leu Asn Leu Ser Gly Val Gly Gly Lys Met
                1445                1450                1455

 Gln Val Gly Gly Asp Gly Val Lys Val Pro Gly Ile Asp Ala Thr
                1460                1465                1470

 Thr Lys Leu Asn Val Gly Ala Pro Asp Val Thr Leu Arg Gly Pro
                1475                1480                1485

 Ser Leu Gln Gly Asp Leu Ala Val Ser Gly Asp Ile Lys Cys Pro
                1490                1495                1500

 Lys Val Ser Val Gly Ala Pro Asp Leu Ser Leu Glu Ala Ser Glu
                1505                1510                1515

 Gly Ser Ile Lys Leu Pro Lys Met Lys Leu Pro Gln Phe Gly Ile
                1520                1525                1530

 Ser Thr Pro Gly Ser Asp Leu His Val Asn Ala Lys Gly Pro Gln
                1535                1540                1545

 Val Ser Gly Glu Leu Lys Gly Pro Gly Val Asp Val Asn Leu Lys
                1550                1555                1560

 Gly Pro Arg Ile Ser Ala Pro Asn Val Asp Phe Asn Leu Glu Gly
                1565                1570                1575

 Pro Lys Val Lys Gly Ser Leu Gly Ala Thr Gly Glu Ile Lys Gly
                1580                1585                1590

 Pro Thr Val Gly Gly Gly Leu Pro Gly Ile Gly Val Gln Gly Leu
                1595                1600                1605

 Glu Gly Asn Leu Gln Met Pro Gly Ile Lys Ser Ser Gly Cys Asp
                1610                1615                1620

 Val Asn Leu Pro Gly Val Asn Val Lys Leu Pro Thr Gly Gln Ile
                1625                1630                1635

 Ser Gly Pro Glu Ile Lys Gly Gly Leu Lys Gly Ser Glu Val Gly
                1640                1645                1650

 Phe His Gly Ala Ala Pro Asp Ile Ser Val Lys Gly Pro Ala Phe
                1655                1660                1665

 Asn Met Ala Ser Pro Glu Ser Asp Phe Gly Ile Asn Leu Lys Gly
                1670                1675                1680

 Pro Lys Ile Lys Gly Gly Ala Asp Val Ser Gly Gly Val Ser Ala
                1685                1690                1695

 Pro Asp Ile Ser Leu Gly Glu Gly His Leu Ser Val Lys Gly Ser
                1700                1705                1710

 Gly Gly Glu Trp Lys Gly Pro Gln Val Ser Ser Ala Leu Asn Leu
                1715                1720                1725

 Asp Thr Ser Lys Phe Ala Gly Gly Leu His Phe Ser Gly Pro Lys
                1730                1735                1740

 Val Glu Gly Gly Val Lys Gly Gly Gln Ile Gly Leu Gln Ala Pro
                1745                1750                1755

 Gly Leu Ser Val Ser Gly Pro Gln Gly His Leu Glu Ser Gly Ser
                1760                1765                1770

 Gly Lys Val Thr Phe Pro Lys Met Lys Ile Pro Lys Phe Thr Phe
                1775                1780                1785

 Ser Gly Arg Glu Leu Val Gly Arg Glu Met Gly Val Asp Val His
                1790                1795                1800

 Phe Pro Lys Ala Glu Ala Ser Ile Gln Ala Gly Ala Gly Asp Gly
                1805                1810                1815

 Glu Trp Glu Glu Ser Glu Val Lys Leu Lys Lys Ser Lys Ile Lys
                1820                1825                1830

 Met Pro Lys Phe Asn Phe Ser Lys Pro Lys Gly Lys Gly Gly Val
                1835                1840                1845

 Thr Gly Ser Pro Glu Ala Ser Ile Ser Gly Ser Lys Gly Asp Leu
                1850                1855                1860

 Lys Ser Ser Lys Ala Ser Leu Gly Ser Leu Glu Gly Glu Ala Glu
                1865                1870                1875

 Ala Glu Ala Ser Ser Pro Lys Gly Lys Phe Ser Leu Phe Lys Ser
                1880                1885                1890

 Lys Lys Pro Arg His Arg Ser Asn Ser Phe Ser Asp Glu Arg Glu
                1895                1900                1905

 Phe Ser Gly Pro Ser Thr Pro Thr Gly Thr Leu Glu Phe Glu Gly
                1910                1915                1920

 Gly Glu Val Ser Leu Glu Gly Gly Lys Val Lys Gly Lys His Gly
                1925                1930                1935

 Lys Leu Lys Phe Gly Thr Phe Gly Gly Leu Gly Ser Lys Ser Lys
                1940                1945                1950

 Gly His Tyr Glu Val Thr Gly Ser Asp Asp Glu Thr Gly Lys Leu
                1955                1960                1965

 Gln Gly Ser Gly Val Ser Leu Ala Ser Lys Lys Ser Arg Leu Ser
                1970                1975                1980

 Ser Ser Ser Ser Asn Asp Ser Gly Asn Lys Val Gly Ile Gln Leu
                1985                1990                1995

 Pro Glu Val Glu Leu Ser Val Ser Thr Lys Lys Glu
                2000                2005

<210> 2486
<211> 1157
<212> DNA
<213> Homo sapien

<400> 2486
 gctcacagtc atcaattata gaccccacaa catgcgccct gaagacagaa 50

 tgttccatat cagagctgtg atcttgagag ccctctcctt ggctttcctg 100

 ctgagtctcc gaggagctgg ggccatcaag gcggaccatg tgtcaactta 150

 tgccgcgttt gtacagacgc atagaccaac aggggagttt atgtttgaat 200

 ttgatgaaga tgagatgttc tatgtggatc tggacaagaa ggagaccgtc 250

 tggcatctgg aggagtttgg ccaagccttt tcctttgagg ctcagggcgg 300

 gctggctaac attgctatat tgaacaacaa cttgaatacc ttgatccagc 350

 gttccaacca cactcaggcc accaacgatc cccctgaggt gaccgtgttt 400

 cccaaggagc ctgtggagct gggccagccc aacaccctca tctgccacat 450

 tgacaagttc ttcccaccag tgctcaacgt cacgtggctg tgcaacgggg 500

 agctggtcac tgagggtgtc gctgagagcc tcttcctgcc cagaacagat 550

 tacagcttcc acaagttcca ttacctgacc tttgtgccct cagcagagga 600

 cttctatgac tgcagggtgg agcactgggg cttggaccag ccgctcctca 650

 agcactggga ggcccaagag ccaatccaga tgcctgagac aacggagact 700

 gtgctctgtg ccctgggcct ggtgctgggc ctagtcggca tcatcgtggg 750

 caccgtcctc atcataaagt ctctgcgttc tggccatgac ccccgggccc 800

 aggggaccct gtgaaatact gtaaaggtga caaaatatct gaacagaaga 850

 ggacttagga gagatctgaa ctccagctgc cctacaaact ccatctcagc 900

 ttttcttctc acttcatgtg aaaactactc cagtggctga ctgaattgct 950

 gacccttcaa gctctgtcct tatccattac ctcaaagcag tcattcctta 1000

 gtaaagtttc caacaaatag aaattaatga cactttggta gcactaatat 1050

 ggagattatc ctttcattga gccttttatc ctctgttctc ctttgaagaa 1100

 cccctcactg tcaccttccc gagaataccc taagaccaat aaatacttca 1150

 gtatttc 1157

<210> 2487
<211> 260
<212> PRT
<213> Homo sapien

<400> 2487
 Met Arg Pro Glu Asp Arg Met Phe His Ile Arg Ala Val Ile Leu
   1               5                  10                  15

 Arg Ala Leu Ser Leu Ala Phe Leu Leu Ser Leu Arg Gly Ala Gly
                  20                  25                  30

 Ala Ile Lys Ala Asp His Val Ser Thr Tyr Ala Ala Phe Val Gln
                  35                  40                  45

 Thr His Arg Pro Thr Gly Glu Phe Met Phe Glu Phe Asp Glu Asp
                  50                  55                  60

 Glu Gln Phe Tyr Val Asp Leu Asp Lys Lys Glu Thr Val Trp His
                  65                  70                  75

 Leu Glu Glu Phe Gly Arg Ala Phe Ser Phe Glu Ala Gln Gly Gly
                  80                  85                  90

 Leu Ala Asn Ile Ala Ile Leu Asn Asn Asn Leu Asn Thr Leu Ile
                  95                 100                 105

 Gln Arg Ser Asn His Thr Gln Ala Ala Asn Asp Pro Pro Glu Val
                 110                 115                 120

 Thr Val Phe Pro Lys Glu Pro Val Glu Leu Gly Gln Pro Asn Thr
                 125                 130                 135

 Leu Ile Cys His Ile Asp Arg Phe Phe Pro Pro Val Leu Asn Val
                 140                 145                 150

 Thr Trp Leu Cys Asn Gly Glu Pro Val Thr Glu Gly Val Ala Glu
                 155                 160                 165

 Ser Leu Phe Leu Pro Arg Thr Asp Tyr Ser Phe His Lys Phe His
                 170                 175                 180

 Tyr Leu Thr Phe Val Pro Ser Ala Glu Asp Val Tyr Asp Cys Arg
                 185                 190                 195

 Val Glu His Trp Gly Leu Asp Gln Pro Leu Leu Lys His Trp Glu
                 200                 205                 210

 Ala Gln Glu Pro Ile Gln Met Pro Glu Thr Thr Glu Thr Val Leu
                 215                 220                 225

 Cys Ala Leu Gly Leu Val Leu Gly Leu Val Gly Ile Ile Val Gly
                 230                 235                 240

 Thr Val Leu Ile Ile Lys Ser Leu Arg Ser Gly His Asp Pro Arg
                 245                 250                 255

 Ala Gln Gly Pro Leu
                 260

<210> 2488
<211> 1157
<212> DNA
<213> Homo sapien

<400> 2488
 gctcacagtc atcaattata gaccccacaa catgcgccct gaagacagaa 50

 tgttccatat cagagctgtg atcttgagag ccctctcctt ggctttcctg 100

 ctgagtctcc gaggagctgg ggccatcaag gcggaccatg tgtcaactta 150

 tgccgcgttt gtacagacgc atagaccaac aggggagttt atgtttgaat 200

 ttgatgaaga tgagatgttc tatgtggatc tggacaagaa ggagaccgtc 250

 tggcatctgg aggagtttgg ccaagccttt tcctttgagg ctcagggcgg 300

 gctggctaac attgctatat tgaacaacaa cttgaatacc ttgatccagc 350

 gttccaacca cactcaggcc accaacgatc cccctgaggt gaccgtgttt 400

 cccaaggagc ctgtggagct gggccagccc aacaccctca tctgccacat 450

 tgacaagttc ttcccaccag tgctcaacgt cacgtggctg tgcaacgggg 500

 agctggtcac tgagggtgtc gctgagagcc tcttcctgcc cagaacagat 550

 tacagcttcc acaagttcca ttacctgacc tttgtgccct cagcagagga 600

 cttctatgac tgcagggtgg agcactgggg cttggaccag ccgctcctca 650

 agcactggga ggcccaagag ccaatccaga tgcctgagac aacggagact 700

 gtgctctgtg ccctgggcct ggtgctgggc ctagtcggca tcatcgtggg 750

 caccgtcctc atcataaagt ctctgcgttc tggccatgac ccccgggccc 800

 aggggaccct gtgaaatact gtaaaggtga caaaatatct gaacagaaga 850

 ggacttagga gagatctgaa ctccagctgc cctacaaact ccatctcagc 900

 ttttcttctc acttcatgtg aaaactactc cagtggctga ctgaattgct 950

 gacccttcaa gctctgtcct tatccattac ctcaaagcag tcattcctta 1000

 gtaaagtttc caacaaatag aaattaatga cactttggta gcactaatat 1050

 ggagattatc ctttcattga gccttttatc ctctgttctc ctttgaagaa 1100

 cccctcactg tcaccttccc gagaataccc taagaccaat aaatacttca 1150

 gtatttc 1157

<210> 2489
<211> 260
<212> PRT
<213> Homo sapien

<400> 2489
 Met Arg Pro Glu Asp Arg Met Phe His Ile Arg Ala Val Ile Leu
   1               5                  10                  15

 Arg Ala Leu Ser Leu Ala Phe Leu Leu Ser Leu Arg Gly Ala Gly
                  20                  25                  30

 Ala Ile Lys Ala Asp His Val Ser Thr Tyr Ala Ala Phe Val Gln
                  35                  40                  45

 Thr His Arg Pro Thr Gly Glu Phe Met Phe Glu Phe Asp Glu Asp
                  50                  55                  60

 Glu Met Phe Tyr Val Asp Leu Asp Lys Lys Glu Thr Val Trp His
                  65                  70                  75

 Leu Glu Glu Phe Gly Gln Ala Phe Ser Phe Glu Ala Gln Gly Gly
                  80                  85                  90

 Leu Ala Asn Ile Ala Ile Leu Asn Asn Asn Leu Asn Thr Leu Ile
                  95                 100                 105

 Gln Arg Ser Asn His Thr Gln Ala Thr Asn Asp Pro Pro Glu Val
                 110                 115                 120

 Thr Val Phe Pro Lys Glu Pro Val Glu Leu Gly Gln Pro Asn Thr
                 125                 130                 135

 Leu Ile Cys His Ile Asp Lys Phe Phe Pro Pro Val Leu Asn Val
                 140                 145                 150

 Thr Trp Leu Cys Asn Gly Glu Leu Val Thr Glu Gly Val Ala Glu
                 155                 160                 165

 Ser Leu Phe Leu Pro Arg Thr Asp Tyr Ser Phe His Lys Phe His
                 170                 175                 180

 Tyr Leu Thr Phe Val Pro Ser Ala Glu Asp Phe Tyr Asp Cys Arg
                 185                 190                 195

 Val Glu His Trp Gly Leu Asp Gln Pro Leu Leu Lys His Trp Glu
                 200                 205                 210

 Ala Gln Glu Pro Ile Gln Met Pro Glu Thr Thr Glu Thr Val Leu
                 215                 220                 225

 Cys Ala Leu Gly Leu Val Leu Gly Leu Val Gly Ile Ile Val Gly
                 230                 235                 240

 Thr Val Leu Ile Ile Lys Ser Leu Arg Ser Gly His Asp Pro Arg
                 245                 250                 255

 Ala Gln Gly Thr Leu
                 260

<210> 2490
<211> 1662
<212> DNA
<213> Rattus norvegicus

<400> 2490
 ggtcgttcgt tgggcggtgc tggtttttcg ctcgtcgact gcggctcttc 50

 ctcgggcagc ggaagcggcg cggcggtcgg agaagtggcc taaaacttcg 100

 gcgttgggtg aaagaaaatg gcccgaacca agcagactgc tcgtaagtcc 150

 accggtggga aagccccccg caaacagctg gccacgaaag ccgccaggaa 200

 aagcgctccc tctaccggcg gggtgaagaa gcctcatcgc tacaggcccg 250

 ggaccgtggc gcttcgagag attcgtcgtt atcagaagtc gaccgagctg 300

 ctcatccgga agctgccctt ccagaggttg gtgagggaga tcgcgcagga 350

 tttcaaaacc gacctgaggt ttcagagcgc agccatcggt gcgctgcagg 400

 aggctagcga agcgtacctg gtgggtctgt tcgaagatac caacctgtgt 450

 gccatccacg ctaagagagt caccatcatg cccaaagaca tccagttggc 500

 tcgccggata cggggagaga gagcttaagt gaaggcagtt tttatggcgt 550

 tttgtagtaa attctgtaaa atactttggt ttaatttgtg actttttttg 600

 taagaaattg tttataatat gttgcatttg tacttaagtc attccatctt 650

 tcactcagga tgaatgcgaa aagtgactgt tcacagacct cagtgatgtg 700

 agcactgttg ctcaggagtg acaagttgct aatatgcaga agggatgggt 750

 gatacttctt gcttctcatg atgcatgttt ctgtatgtta atgacttgtt 800

 gggtagctat taaggtacta gagttgataa atgtgtacag ggtccttttg 850

 caataaaact ggttatgact tgatccaagt gtttaacaat tggggctgtt 900

 aagtctgacc atacatcact gtgatagaat gtgggctttt tcaagggtga 950

 agatacaagt cttaaccaca gtgtaactta cagtttcctt taaaaaaaaa 1000

 aaaagtaaac ctggcagcta tagaatacac tatgtgcatt tataatagct 1050

 attttatata ttgtagtatc aacattttta aattaaatgt tttacattca 1100

 caagtggtgg ggagtcttgt cattaaggtg tgtgtaattt agagtccagt 1150

 tggttttctt ctgactgcac ttgttctcat agtagtaaaa tgctatgcgc 1200

 atttatacct tgcataagtc ctcattctac cacatgttaa ccctctagct 1250

 gataatgcaa acactaactg ggggatttta tttataaggg ctctagaaaa 1300

 aacgagttat tcacaccagc atcatcttaa ctaacattct gaactagtta 1350

 gtgcagcttt tcattgtgtt gtgtggttgg tctcataact aggttgagtt 1400

 tttctcctct gctgaggaaa cagtaccgaa gttctttttc ttgtggcatt 1450

 tgtattataa aaacttggtg tgggggagga gcacaaaact ccagcccact 1500

 gaacctctgc caattaagat ggtgttgggt taggttacat ctggttactg 1550

 tcctgggaaa atcattttta tagagatggc cttccaagtg gttttaaaat 1600

 ttactgaagt ttttaggtca attatgtatg ttgactaaat ttacaaataa 1650

 acttgtttat cc 1662

<210> 2491
<211> 136
<212> PRT
<213> Rattus norvegicus

<400> 2491
 Met Ala Arg Thr Lys Gln Thr Ala Arg Lys Ser Thr Gly Gly Lys
   1               5                  10                  15

 Ala Pro Arg Lys Gln Leu Ala Thr Lys Ala Ala Arg Lys Ser Ala
                  20                  25                  30

 Pro Ser Thr Gly Gly Val Lys Lys Pro His Arg Tyr Arg Pro Gly
                  35                  40                  45

 Thr Val Ala Leu Arg Glu Ile Arg Arg Tyr Gln Lys Ser Thr Glu
                  50                  55                  60

 Leu Leu Ile Arg Lys Leu Pro Phe Gln Arg Leu Val Arg Glu Ile
                  65                  70                  75

 Ala Gln Asp Phe Lys Thr Asp Leu Arg Phe Gln Ser Ala Ala Ile
                  80                  85                  90

 Gly Ala Leu Gln Glu Ala Ser Glu Ala Tyr Leu Val Gly Leu Phe
                  95                 100                 105

 Glu Asp Thr Asn Leu Cys Ala Ile His Ala Lys Arg Val Thr Ile
                 110                 115                 120

 Met Pro Lys Asp Ile Gln Leu Ala Arg Arg Ile Arg Gly Glu Arg
                 125                 130                 135

 Ala


<210> 2492
<211> 2113
<212> DNA
<213> Homo sapien

<400> 2492
 gtgcggttgg gaacgcggag cggacggatt cgattcaacg gggttccgga 50

 ccgcgctgcg ctatggagca ggtcaatgag ctgaaggaga aaggcaacaa 100

 ggccctgagc gtgggtaaca tcgatgatgc cttacagtgc tactccgaag 150

 ctattaagct ggatccccac aaccacgtgc tgtacagcaa ccgttctgct 200

 gcctatgcca agaaaggaga ctaccagaag gcttatgagg atggctgcaa 250

 gactgtcgac ctaaagcctg actggggcaa gggctattca cgaaaagcag 300

 cagctctaga gttcttaaac cgctttgaag aagccaagcg aacctatgag 350

 gagggcttaa aacacgaggc aaataaccct caactgaaag agggtttaca 400

 gaatatggag gccaggttgg cagagagaaa attcatgaac cctttcaaca 450

 tgcctaatct gtatcagaag ttggagagtg atcccaggac aaggacacta 500

 ctcagtgatc ctacctaccg ggagctgata gagcagctac gaaacaagcc 550

 ttctgacctg ggcacgaaac tacaagatcc ccggatcatg accactctca 600

 gcgtcctcct tggggtcgat ctgggcagta tggatgagga ggaagagatt 650

 gcaacacctc caccaccacc ccctcccaaa aaggagacca agccagagcc 700

 aatggaagaa gatcttccag agaataagaa gcaggcactg aaagaaaaag 750

 agctggggaa cgatgcctac aagaagaaag actttgacac agccttgaag 800

 cattacgaca aagccaagga gctggacccc actaacatga cttacattac 850

 caatcaagca gcggtatact ttgaaaaggg cgactacaat aagtgccggg 900

 agctttgtga gaaggccatt gaagtgggga gagaaaaccg agaagactat 950

 cgacagattg ccaaagcata tgctcgaatt ggcaactcct acttcaaaga 1000

 agaaaagtac aaggatgcca tccatttcta taacaagtct ctggcagagc 1050

 accgaacccc agatgtgctc aagaaatgcc agcaggcaga gaaaatcctg 1100

 aaggagcaag agcggctggc ctacataaac cccgacctgg ctttggagga 1150

 gaagaacaaa ggcaacgagt gttttcagaa aggggactat ccccaggcca 1200

 tgaagcatta tacagaagcc atcaaaagga acccgaaaga tgccaaatta 1250

 tacagcaatc gagctgcctg ctacaccaaa ctcctggagt tccagctggc 1300

 actcaaggac tgtgaggaat gtatccagct ggagccgacc ttcatcaagg 1350

 gttatacacg gaaagccgct gcgctggaag cgatgaagga ctacaccaaa 1400

 gccatggatg tgtaccagaa ggcgctagac ctggactcca gctgtaagga 1450

 ggcggcagac ggctaccagc gctgtatgat ggcgcagtac aaccggcacg 1500

 acagccccga agatgtgaag cgacgagcca tggccgaccc tgaggtgcag 1550

 cagatcatga gtgacccagc catgcgcctt atcctggaac agatgcagaa 1600

 ggacccccag gcactcagcg aacacttaaa gaatcctgta atagcacaga 1650

 agatccagaa gctgatggat gtgggtctga ttgcaattcg gtgatgactt 1700

 gttcatcccc ccttcccttc gccctcatgt ggaaagagga gctgggaccg 1750

 cggcgagcag cacggagcgg aagggagagc aggggagaga aggcctcatc 1800

 tctctatatt tatacataac cccggggaag acacagagac tcgtacctgc 1850

 gctgtttgtg ccgccgctgc ctctgggccc tcccagcaca cgcatggtct 1900

 cttcaccgct gccctcgagt tccatgtctc tttcccctgc ccctagttgc 1950

 tgtctcggct gctctcccat agttggtttt ttttttattt ggggcagtgg 2000

 gcatgttatg gggaggggag ggggttcttc cagcctcagg tcccagctgt 2050

 ctcacgttgt ttattctgcg tccccttctc caataaaaca agccagttgg 2100

 gcgtggttat aac 2113

<210> 2493
<211> 543
<212> PRT
<213> Homo sapien

<400> 2493
 Met Glu Gln Val Asn Glu Leu Lys Glu Lys Gly Asn Lys Ala Leu
   1               5                  10                  15

 Ser Val Gly Asn Ile Asp Asp Ala Leu Gln Cys Tyr Ser Glu Ala
                  20                  25                  30

 Ile Lys Leu Asp Pro His Asn His Val Leu Tyr Ser Asn Arg Ser
                  35                  40                  45

 Ala Ala Tyr Ala Lys Lys Gly Asp Tyr Gln Lys Ala Tyr Glu Asp
                  50                  55                  60

 Gly Cys Lys Thr Val Asp Leu Lys Pro Asp Trp Gly Lys Gly Tyr
                  65                  70                  75

 Ser Arg Lys Ala Ala Ala Leu Glu Phe Leu Asn Arg Phe Glu Glu
                  80                  85                  90

 Ala Lys Arg Thr Tyr Glu Glu Gly Leu Lys His Glu Ala Asn Asn
                  95                 100                 105

 Pro Gln Leu Lys Glu Gly Leu Gln Asn Met Glu Ala Arg Leu Ala
                 110                 115                 120

 Glu Arg Lys Phe Met Asn Pro Phe Asn Met Pro Asn Leu Tyr Gln
                 125                 130                 135

 Lys Leu Glu Ser Asp Pro Arg Thr Arg Thr Leu Leu Ser Asp Pro
                 140                 145                 150

 Thr Tyr Arg Glu Leu Ile Glu Gln Leu Arg Asn Lys Pro Ser Asp
                 155                 160                 165

 Leu Gly Thr Lys Leu Gln Asp Pro Arg Ile Met Thr Thr Leu Ser
                 170                 175                 180

 Val Leu Leu Gly Val Asp Leu Gly Ser Met Asp Glu Glu Glu Glu
                 185                 190                 195

 Ile Ala Thr Pro Pro Pro Pro Pro Pro Pro Lys Lys Glu Thr Lys
                 200                 205                 210

 Pro Glu Pro Met Glu Glu Asp Leu Pro Glu Asn Lys Lys Gln Ala
                 215                 220                 225

 Leu Lys Glu Lys Glu Leu Gly Asn Asp Ala Tyr Lys Lys Lys Asp
                 230                 235                 240

 Phe Asp Thr Ala Leu Lys His Tyr Asp Lys Ala Lys Glu Leu Asp
                 245                 250                 255

 Pro Thr Asn Met Thr Tyr Ile Thr Asn Gln Ala Ala Val Tyr Phe
                 260                 265                 270

 Glu Lys Gly Asp Tyr Asn Lys Cys Arg Glu Leu Cys Glu Lys Ala
                 275                 280                 285

 Ile Glu Val Gly Arg Glu Asn Arg Glu Asp Tyr Arg Gln Ile Ala
                 290                 295                 300

 Lys Ala Tyr Ala Arg Ile Gly Asn Ser Tyr Phe Lys Glu Glu Lys
                 305                 310                 315

 Tyr Lys Asp Ala Ile His Phe Tyr Asn Lys Ser Leu Ala Glu His
                 320                 325                 330

 Arg Thr Pro Asp Val Leu Lys Lys Cys Gln Gln Ala Glu Lys Ile
                 335                 340                 345

 Leu Lys Glu Gln Glu Arg Leu Ala Tyr Ile Asn Pro Asp Leu Ala
                 350                 355                 360

 Leu Glu Glu Lys Asn Lys Gly Asn Glu Cys Phe Gln Lys Gly Asp
                 365                 370                 375

 Tyr Pro Gln Ala Met Lys His Tyr Thr Glu Ala Ile Lys Arg Asn
                 380                 385                 390

 Pro Lys Asp Ala Lys Leu Tyr Ser Asn Arg Ala Ala Cys Tyr Thr
                 395                 400                 405

 Lys Leu Leu Glu Phe Gln Leu Ala Leu Lys Asp Cys Glu Glu Cys
                 410                 415                 420

 Ile Gln Leu Glu Pro Thr Phe Ile Lys Gly Tyr Thr Arg Lys Ala
                 425                 430                 435

 Ala Ala Leu Glu Ala Met Lys Asp Tyr Thr Lys Ala Met Asp Val
                 440                 445                 450

 Tyr Gln Lys Ala Leu Asp Leu Asp Ser Ser Cys Lys Glu Ala Ala
                 455                 460                 465

 Asp Gly Tyr Gln Arg Cys Met Met Ala Gln Tyr Asn Arg His Asp
                 470                 475                 480

 Ser Pro Glu Asp Val Lys Arg Arg Ala Met Ala Asp Pro Glu Val
                 485                 490                 495

 Gln Gln Ile Met Ser Asp Pro Ala Met Arg Leu Ile Leu Glu Gln
                 500                 505                 510

 Met Gln Lys Asp Pro Gln Ala Leu Ser Glu His Leu Lys Asn Pro
                 515                 520                 525

 Val Ile Ala Gln Lys Ile Gln Lys Leu Met Asp Val Gly Leu Ile
                 530                 535                 540

 Ala Ile Arg


<210> 2494
<211> 2265
<212> DNA
<213> Homo sapien

<400> 2494
 cggcccagcg gaccccagcc tctgccaggt tcggtccgcc atcctcgtcc 50

 cgtcctccgc cggcccctgc cccgcgccca gggatcctcc agctcctttc 100

 gcccgcgccc tccgttcgct ccggacacca tggacaagtt ttggtggcac 150

 gcagcctggg gactctgcct cgtgccgctg agcctggcgc agatcgattt 200

 gaatataacc tgccgctttg caggtgtatt ccacgtggag aaaaatggtc 250

 gctacagcat ctctcggacg gaggccgctg acctctgcaa ggctttcaat 300

 agcaccttgc ccacaatggc ccagatggag aaagctctga gcatcggatt 350

 tgagacctgc aggtatgggt tcatagaagg gcacgtggtg attccccgga 400

 tccaccccaa ctccatctgt gcagcaaaca acacaggggt gtacatcctc 450

 acatccaaca cctcccagta tgacacatat tgcttcaatg cttcagctcc 500

 acctgaagaa gattgtacat cagtcacaga cctgcccaat gcctttgatg 550

 gaccaattac cataactatt gttaaccgtg atggcacccg ctatgtccag 600

 aaaggagaat acagaacgaa tcctgaagac atctacccca gcaaccctac 650

 tgatgatgac gtgagcagcg gctcctccag tgaaaggagc agcacttcag 700

 gaggttacat cttttacacc ttttctactg tacaccccat cccagacgaa 750

 gacagtccct ggatcaccga cagcacagac agaatccctg ctaccagtac 800

 gtcttcaaat accatctcag caggctggga gccaaatgaa gaaaatgaag 850

 atgaaagaga cagacacctc agtttttctg gatcaggcat tgatgatgat 900

 gaagatttta tctccagcac catttcaacc acaccacggg cttttgacca 950

 cacaaaacag aaccaggact ggacccagtg gaacccaagc cattcaaatc 1000

 cggaagtgct acttcagaca accacaagga tgactgatgt agacagaaat 1050

 ggcaccactg cttatgaagg aaactggaac ccagaagcac accctcccct 1100

 cattcaccat gagcatcatg aggaagaaga gaccccacat tctacaagca 1150

 caatccaggc aactcctagt agtacaacgg aagaaacagc tacccagaag 1200

 gaacagtggt ttggcaacag atggcatgtg ggatatcgcc aaacacccaa 1250

 agaagactcc cattcgacaa cagggacagc tgcagcctca gctcatacca 1300

 gccatccaat gcaaggaagg acaacaccaa gcccagagga cagttcctgg 1350

 actgatttct tcaacccaat ctcacacccc atgggacgag gtcatcaagc 1400

 aggaagaagg atggatatgg actccagtca tagtacaacg cttcagccta 1450

 ctgcaaatcc aaacacaggt ttggtggaag atttggacag gacaggacct 1500

 ctttcaatga caacgcagca gagtaattct cagagcttct ctacatcaca 1550

 tgaaggcttg gaagaagata aagaccatcc aacaacttct actctgacat 1600

 caagcaatag gaatgatgtc acaggtggaa gaagagaccc aaatcattct 1650

 gaaggctcaa ctactttact ggaaggttat acctctcatt acccacacac 1700

 gaaggaaagc aggaccttca tcccagtgac ctcagctaag actgggtcct 1750

 ttggagttac tgcagttact gttggagatt ccaactctaa tgtcaatcgt 1800

 tccttatcag gagaccaaga cacattccac cccagtgggg ggtcccatac 1850

 cactcatgga tctgaatcag atggacactc acatgggagt caagaaggtg 1900

 gagcaaacac aacctctggt cctataagga caccccaaat tccagaatgg 1950

 ctgatcatct tggcatccct cttggccttg gctttgattc ttgcagtttg 2000

 cattgcagtc aacagtcgaa gaaggtgtgg gcagaagaaa aagctagtga 2050

 tcaacagtgg caatggagct gtggaggaca gaaagccaag tggactcaac 2100

 ggagaggcca gcaagtctca ggaaatggtg catttggtga acaaggagtc 2150

 gtcagaaact ccagaccagt ttatgacagc tgatgagaca aggaacctgc 2200

 agaatgtgga catgaagatt ggggtgtaac acctacacca ttatcttgga 2250

 aagaaacaac cgttg 2265

<210> 2495
<211> 699
<212> PRT
<213> Homo sapien

<400> 2495
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val
   1               5                  10                  15

 Pro Leu Ser Leu Ala Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe
                  20                  25                  30

 Ala Gly Val Phe His Val Glu Lys Asn Gly Arg Tyr Ser Ile Ser
                  35                  40                  45

 Arg Thr Glu Ala Ala Asp Leu Cys Lys Ala Phe Asn Ser Thr Leu
                  50                  55                  60

 Pro Thr Met Ala Gln Met Glu Lys Ala Leu Ser Ile Gly Phe Glu
                  65                  70                  75

 Thr Cys Arg Tyr Gly Phe Ile Glu Gly His Val Val Ile Pro Arg
                  80                  85                  90

 Ile His Pro Asn Ser Ile Cys Ala Ala Asn Asn Thr Gly Val Tyr
                  95                 100                 105

 Ile Leu Thr Ser Asn Thr Ser Gln Tyr Asp Thr Tyr Cys Phe Asn
                 110                 115                 120

 Ala Ser Ala Pro Pro Glu Glu Asp Cys Thr Ser Val Thr Asp Leu
                 125                 130                 135

 Pro Asn Ala Phe Asp Gly Pro Ile Thr Ile Thr Ile Val Asn Arg
                 140                 145                 150

 Asp Gly Thr Arg Tyr Val Gln Lys Gly Glu Tyr Arg Thr Asn Pro
                 155                 160                 165

 Glu Asp Ile Tyr Pro Ser Asn Pro Thr Asp Asp Asp Val Ser Ser
                 170                 175                 180

 Gly Ser Ser Ser Glu Arg Ser Ser Thr Ser Gly Gly Tyr Ile Phe
                 185                 190                 195

 Tyr Thr Phe Ser Thr Val His Pro Ile Pro Asp Glu Asp Ser Pro
                 200                 205                 210

 Trp Ile Thr Asp Ser Thr Asp Arg Ile Pro Ala Thr Ser Thr Ser
                 215                 220                 225

 Ser Asn Thr Ile Ser Ala Gly Trp Glu Pro Asn Glu Glu Asn Glu
                 230                 235                 240

 Asp Glu Arg Asp Arg His Leu Ser Phe Ser Gly Ser Gly Ile Asp
                 245                 250                 255

 Asp Asp Glu Asp Phe Ile Ser Ser Thr Ile Ser Thr Thr Pro Arg
                 260                 265                 270

 Ala Phe Asp His Thr Lys Gln Asn Gln Asp Trp Thr Gln Trp Asn
                 275                 280                 285

 Pro Ser His Ser Asn Pro Glu Val Leu Leu Gln Thr Thr Thr Arg
                 290                 295                 300

 Met Thr Asp Val Asp Arg Asn Gly Thr Thr Ala Tyr Glu Gly Asn
                 305                 310                 315

 Trp Asn Pro Glu Ala His Pro Pro Leu Ile His His Glu His His
                 320                 325                 330

 Glu Glu Glu Glu Thr Pro His Ser Thr Ser Thr Ile Gln Ala Thr
                 335                 340                 345

 Pro Ser Ser Thr Thr Glu Glu Thr Ala Thr Gln Lys Glu Gln Trp
                 350                 355                 360

 Phe Gly Asn Arg Trp His Val Gly Tyr Arg Gln Thr Pro Lys Glu
                 365                 370                 375

 Asp Ser His Ser Thr Thr Gly Thr Ala Ala Ala Ser Ala His Thr
                 380                 385                 390

 Ser His Pro Met Gln Gly Arg Thr Thr Pro Ser Pro Glu Asp Ser
                 395                 400                 405

 Ser Trp Thr Asp Phe Phe Asn Pro Ile Ser His Pro Met Gly Arg
                 410                 415                 420

 Gly His Gln Ala Gly Arg Arg Met Asp Met Asp Ser Ser His Ser
                 425                 430                 435

 Thr Thr Leu Gln Pro Thr Ala Asn Pro Asn Thr Gly Leu Val Glu
                 440                 445                 450

 Asp Leu Asp Arg Thr Gly Pro Leu Ser Met Thr Thr Gln Gln Ser
                 455                 460                 465

 Asn Ser Gln Ser Phe Ser Thr Ser His Glu Gly Leu Glu Glu Asp
                 470                 475                 480

 Lys Asp His Pro Thr Thr Ser Thr Leu Thr Ser Ser Asn Arg Asn
                 485                 490                 495

 Asp Val Thr Gly Gly Arg Arg Asp Pro Asn His Ser Glu Gly Ser
                 500                 505                 510

 Thr Thr Leu Leu Glu Gly Tyr Thr Ser His Tyr Pro His Thr Lys
                 515                 520                 525

 Glu Ser Arg Thr Phe Ile Pro Val Thr Ser Ala Lys Thr Gly Ser
                 530                 535                 540

 Phe Gly Val Thr Ala Val Thr Val Gly Asp Ser Asn Ser Asn Val
                 545                 550                 555

 Asn Arg Ser Leu Ser Gly Asp Gln Asp Thr Phe His Pro Ser Gly
                 560                 565                 570

 Gly Ser His Thr Thr His Gly Ser Glu Ser Asp Gly His Ser His
                 575                 580                 585

 Gly Ser Gln Glu Gly Gly Ala Asn Thr Thr Ser Gly Pro Ile Arg
                 590                 595                 600

 Thr Pro Gln Ile Pro Glu Trp Leu Ile Ile Leu Ala Ser Leu Leu
                 605                 610                 615

 Ala Leu Ala Leu Ile Leu Ala Val Cys Ile Ala Val Asn Ser Arg
                 620                 625                 630

 Arg Arg Cys Gly Gln Lys Lys Lys Leu Val Ile Asn Ser Gly Asn
                 635                 640                 645

 Gly Ala Val Glu Asp Arg Lys Pro Ser Gly Leu Asn Gly Glu Ala
                 650                 655                 660

 Ser Lys Ser Gln Glu Met Val His Leu Val Asn Lys Glu Ser Ser
                 665                 670                 675

 Glu Thr Pro Asp Gln Phe Met Thr Ala Asp Glu Thr Arg Asn Leu
                 680                 685                 690

 Gln Asn Val Asp Met Lys Ile Gly Val
                 695

<210> 2496
<211> 12515
<212> DNA
<213> Homo sapien

<400> 2496
 ctaccgggcg gaggtgagcg cggcgccggc tcctcctgcg gcggactttg 50

 ggtgcgactt gacgagcggt ggttcgacaa gtggccttgc gggccggatc 100

 gtcccagtgg aagagttgta aatttgcttc tggccttccc ctacggatta 150

 tacctggcct tcccctacgg attatactca acttactgtt tagaaaatgt 200

 ggcccacgag acgcctggtt actatcaaaa ggagcggggt cgacggtccc 250

 cactttcccc tgagcctcag cacctgcttg tttggaaggg gtattgaatg 300

 tgacatccgt atccagcttc ctgttgtgtc aaaacaacat tgcaaaattg 350

 aaatccatga gcaggaggca atattacata atttcagttc cacaaatcca 400

 acacaagtaa atgggtctgt tattgatgag cctgtacggc taaaacatgg 450

 agatgtaata actattattg atcgttcctt caggtatgaa aatgaaagtc 500

 ttcagaatgg aaggaagtca actgaatttc caagaaaaat acgtgaacag 550

 gagccagcac gtcgtgtctc aagatctagc ttctcttctg accctgatga 600

 gaaagctcaa gattccaagg cctattcaaa aatcactgaa ggaaaagttt 650

 caggaaatcc tcaggtacat atcaagaatg tcaaagaaga cagtaccgca 700

 gatgactcaa aagacagtgt tgctcaggga acaactaatg ttcattcctc 750

 agaacatgct ggacgtaatg gcagaaatgc agctgatccc atttctgggg 800

 attttaaaga aatttccagc gttaaattag tgagccgtta tggagaattg 850

 aagtctgttc ccactacaca atgtcttgac aatagcaaaa aaaatgaatc 900

 tcccttttgg aagctttatg agtcagtgaa gaaagagttg gatgtaaaat 950

 cacaaaaaga aaatgtccta cagtattgta gaaaatctgg attacaaact 1000

 gattacgcaa cagagaaaga aagtgctgat ggtttacagg gggagaccca 1050

 actgttggtc tcgcgtaagt caagaccaaa atctggtggg agcggccacg 1100

 ctgtggcaga gcctgcttca cctgaacaag agcttgacca gaacaagggg 1150

 aagggaagag acgtggagtc tgttcagact cccagcaagg ctgtgggcgc 1200

 cagctttcct ctctatgagc cggctaaaat gaagacccct gtacaatatt 1250

 cacagcaaca aaattctcca caaaaacata agaacaaaga cctgtatact 1300

 actggtagaa gagaatctgt gaatctgggt aaaagtgaag gcttcaaggc 1350

 tggtgataaa actcttactc ccaggaagct ttcaactaga aatcgaacac 1400

 cagctaaagt tgaagatgca gctgactctg ccactaagcc agaaaatctc 1450

 tcttccaaaa ccagaggaag tattcctaca gatgtggaag ttctgcctac 1500

 ggaaactgaa attcacaatg agccattttt aactctgtgg ctcactcaag 1550

 ttgagaggaa gatccaaaag gattccctca gcaagcctga gaaattgggc 1600

 actacagctg gacagatgtg ctctgggtta cctggtctta gttcagttga 1650

 tatcaacaac tttggtgatt ccattaatga gagtgaggga atacctttga 1700

 aaagaaggcg tgtgtccttt ggtgggcacc taagacctga actatttgat 1750

 gaaaacttgc ctcctaatac gcctctcaaa aggggagaag ccccaaccaa 1800

 aagaaagtct ctggtaatgc acactccacc tgtcctgaag aaaatcatca 1850

 aggaacagcc tcaaccatca ggaaaacaag agtcaggttc agaaatccat 1900

 gtggaagtga aggcacaaag cttggttata agccctccag ctcctagtcc 1950

 taggaaaact ccagttgcca gtgatcaacg ccgtaggtcc tgcaaaacag 2000

 cccctgcttc cagcagcaaa tctcagacag aggttcctaa gagaggagga 2050

 gaaagagtgg caacctgcct tcaaaagaga gtgtctatca gccgaagtca 2100

 acatgatatt ttacagatga tatgttccaa aagaagaagt ggtgcttcgg 2150

 aagcaaatct gattgttgca aaatcatggg cagatgtagt aaaacttggt 2200

 gcaaaacaaa cacaaactaa agtcataaaa catggtcctc aaaggtcaat 2250

 gaacaaaagg caaagaagac ctgctactcc aaagaagcct gtgggcgaag 2300

 ttcacagtca atttagtaca ggccacgcaa actctccttg taccataata 2350

 atagggaaag ctcatactga aaaagtacat gtgcctgctc gaccctacag 2400

 agtgctcaac aacttcattt ccaaccaaaa aatggacttt aaggaagatc 2450

 tttcaggaat agctgaaatg ttcaagaccc cagtgaagga gcaaccgcag 2500

 ttgacaagca catgtcacat cgctatttca aattcagaga atttgcttgg 2550

 aaaacagttt caaggaactg attcaggaga agaacctctg ctccccacct 2600

 cagagagttt tggaggaaat gtgttcttca gtgcacagaa tgcagcaaaa 2650

 cagccatctg ataaatgctc tgcaagccct cccttaagac ggcagtgtat 2700

 tagagaaaat ggaaacgtag caaaaacgcc caggaacacc tacaaaatga 2750

 cttctctgga gacaaaaact tcagatactg agacagagcc ttcaaaaaca 2800

 gtatccactg taaacaggtc aggaaggtct acagagttca ggaatataca 2850

 gaagctacct gtggaaagta agagtgaaga aacaaataca gaaattgttg 2900

 agtgcatcct aaaaagaggt cagaaggcaa cactactaca acaaaggaga 2950

 gaaggagaga tgaaggaaat agaaagacct tttgagacat ataaggaaaa 3000

 tattgaatta aaagaaaacg atgaaaagat gaaagcaatg aagagatcaa 3050

 gaacttgggg gcagaaatgt gcaccaatgt ctgacctgac agacctcaag 3100

 agcttgcctg atacagaact catgaaagac acggcacgtg gccagaatct 3150

 cctccaaacc caagatcatg ccaaggcacc aaagagtgag aaaggcaaaa 3200

 tcactaaaat gccctgccag tcattacaac cagaaccaat aaacacccca 3250

 acacacacaa aacaacagtt gaaggcatcc ctggggaaag taggtgtgaa 3300

 agaagagctc ctagcagtcg gcaagttcac acggacgtca ggggagacca 3350

 cgcacacgca cagagagcca gcaggagatg gcaagagcat cagaacgttt 3400

 aaggagtctc caaagcagat cctggaccca gcagcccgtg taactggaat 3450

 gaagaagtgg ccaagaacgc ctaaggaaga ggcccagtca ctagaagacc 3500

 tggctggctt caaagagctc ttccagacac caggtccctc tgaggaatca 3550

 atgactgatg agaaaactac caaaatagcc tgcaaatctc caccaccaga 3600

 atcagtggac actccaacaa gcacaaagca atggcctaag agaagtctca 3650

 ggaaagcaga tgtagaggaa gaattcttag cactcaggaa actaacacca 3700

 tcagcaggga aagccatgct tacgcccaaa ccagcaggag gtgatgagaa 3750

 agacattaaa gcatttatgg gaactccagt gcagaaactg gacctggcag 3800

 gaactttacc tggcagcaaa agacagctac agactcctaa ggaaaaggcc 3850

 caggctctag aagacctggc tggctttaaa gagctcttcc agactcctgg 3900

 tcacaccgag gaattagtgg ctgctggtaa aaccactaaa ataccctgcg 3950

 actctccaca gtcagaccca gtggacaccc caacaagcac aaagcaacga 4000

 cccaagagaa gtatcaggaa agcagatgta gagggagaac tcttagcgtg 4050

 caggaatcta atgccatcag caggcaaagc catgcacacg cctaaaccat 4100

 cagtaggtga agagaaagac atcatcatat ttgtgggaac tccagtgcag 4150

 aaactggacc tgacagagaa cttaaccggc agcaagagac ggccacaaac 4200

 tcctaaggaa gaggcccagg ctctggaaga cctgactggc tttaaagagc 4250

 tcttccagac ccctggtcat actgaagaag cagtggctgc tggcaaaact 4300

 actaaaatgc cctgcgaatc ttctccacca gaatcagcag acaccccaac 4350

 aagcacaaga aggcagccca agacaccttt ggagaaaagg gacgtacaga 4400

 aggagctctc agccctgaag aagctcacac agacatcagg ggaaaccaca 4450

 cacacagata aagtaccagg aggtgaggat aaaagcatca acgcgtttag 4500

 ggaaactgca aaacagaaac tggacccagc agcaagtgta actggtagca 4550

 agaggcaccc aaaaactaag gaaaaggccc aacccctaga agacctggct 4600

 ggctggaaag agctcttcca gacaccagta tgcactgaca agcccacgac 4650

 tcacgagaaa actaccaaaa tagcctgcag atcacaacca gacccagtgg 4700

 acacaccaac aagctccaag ccacagtcca agagaagtct caggaaagtg 4750

 gacgtagaag aagaattctt cgcactcagg aaacgaacac catcagcagg 4800

 caaagccatg cacacaccca aaccagcagt aagtggtgag aaaaacatct 4850

 acgcatttat gggaactcca gtgcagaaac tggacctgac agagaactta 4900

 actggcagca agagacggct acaaactcct aaggaaaagg cccaggctct 4950

 agaagacctg gctggcttta aagagctctt ccagacacga ggtcacactg 5000

 aggaatcaat gactaacgat aaaactgcca aagtagcctg caaatcttca 5050

 caaccagacc tagacaaaaa cccagcaagc tccaagcgac ggctcaagac 5100

 atccctgggg aaagtgggcg tgaaagaaga gctcctagca gttggcaagc 5150

 tcacacagac atcaggagag actacacaca cacacacaga gccaacagga 5200

 gatggtaaga gcatgaaagc atttatggag tctccaaagc agatcttaga 5250

 ctcagcagca agtctaactg gcagcaagag gcagctgaga actcctaagg 5300

 gaaagtctga agtccctgaa gacctggccg gcttcatcga gctcttccag 5350

 acaccaagtc acactaagga atcaatgact aatgaaaaaa ctaccaaagt 5400

 atcctacaga gcttcacagc cagacctagt ggacacccca acaagctcca 5450

 agccacagcc caagagaagt ctcaggaaag cagacactga agaagaattt 5500

 ttagcattta ggaaacaaac gccatcagca ggcaaagcca tgcacacacc 5550

 caaaccagca gtaggtgaag agaaagacat caacacgttt ttgggaactc 5600

 cagtgcagaa actggaccag ccaggaaatt tacctggcag caatagacgg 5650

 ctacaaactc gtaaggaaaa ggcccaggct ctagaagaac tgactggctt 5700

 cagagagctt ttccagacac catgcactga taaccccaca gctgatgaga 5750

 aaactaccaa aaaaatactc tgcaaatctc cgcaatcaga cccagcggac 5800

 accccaacaa acacaaagca acggcccaag agaagcctca agaaagcaga 5850

 cgtagaggaa gaatttttag cattcaggaa actaacacca tcagcaggca 5900

 aagccatgca cacgcctaaa gcagcagtag gtgaagagaa agacatcaac 5950

 acatttgtgg ggactccagt ggagaaactg gacctgctag gaaatttacc 6000

 tggcagcaag agacggccac aaactcctaa agaaaaggcc aaggctctag 6050

 aagatctggc tggcttcaaa gagctcttcc agacaccagg tcacactgag 6100

 gaatcaatga ccgatgacaa aatcacagaa gtatcctgca aatctccaca 6150

 accagaccca gtcaaaaccc caacaagctc caagcaacga ctcaagatat 6200

 ccttggggaa agtaggtgtg aaagaagagg tcctaccagt cggcaagctc 6250

 acacagacgt cagggaagac cacacagaca cacagagaga cagcaggaga 6300

 tggaaagagc atcaaagcgt ttaaggaatc tgcaaagcag atgctggacc 6350

 cagcaaacta tggaactggg atggagaggt ggccaagaac acctaaggaa 6400

 gaggcccaat cactagaaga cctggccggc ttcaaagagc tcttccagac 6450

 accagaccac actgaggaat caacaactga tgacaaaact accaaaatag 6500

 cctgcaaatc tccaccacca gaatcaatgg acactccaac aagcacaagg 6550

 aggcggccca aaacaccttt ggggaaaagg gatatagtgg aagagctctc 6600

 agccctgaag cagctcacac agaccacaca cacagacaaa gtaccaggag 6650

 atgaggataa aggcatcaac gtgttcaggg aaactgcaaa acagaaactg 6700

 gacccagcag caagtgtaac tggtagcaag aggcagccaa gaactcctaa 6750

 gggaaaagcc caacccctag aagacttggc tggcttgaaa gagctcttcc 6800

 agacaccagt atgcactgac aagcccacga ctcacgagaa aactaccaaa 6850

 atagcctgca gatctccaca accagaccca gtgggtaccc caacaatctt 6900

 caagccacag tccaagagaa gtctcaggaa agcagacgta gaggaagaat 6950

 ccttagcact caggaaacga acaccatcag tagggaaagc tatggacaca 7000

 cccaaaccag caggaggtga tgagaaagac atgaaagcat ttatgggaac 7050

 tccagtgcag aaattggacc tgccaggaaa tttacctggc agcaaaagat 7100

 ggccacaaac tcctaaggaa aaggcccagg ctctagaaga cctggctggc 7150

 ttcaaagagc tcttccagac accaggcact gacaagccca cgactgatga 7200

 gaaaactacc aaaatagcct gcaaatctcc acaaccagac ccagtggaca 7250

 ccccagcaag cacaaagcaa cggcccaaga gaaacctcag gaaagcagac 7300

 gtagaggaag aatttttagc actcaggaaa cgaacaccat cagcaggcaa 7350

 agccatggac accccaaaac cagcagtaag tgatgagaaa aatatcaaca 7400

 catttgtgga aactccagtg cagaaactgg acctgctagg aaatttacct 7450

 ggcagcaaga gacagccaca gactcctaag gaaaaggctg aggctctaga 7500

 ggacctggtt ggcttcaaag aactcttcca gacaccaggt cacactgagg 7550

 aatcaatgac tgatgacaaa atcacagaag tatcctgtaa atctccacag 7600

 ccagagtcat tcaaaacctc aagaagctcc aagcaaaggc tcaagatacc 7650

 cctggtgaaa gtggacatga aagaagagcc cctagcagtc agcaagctca 7700

 cacggacatc aggggagact acgcaaacac acacagagcc aacaggagat 7750

 agtaagagca tcaaagcgtt taaggagtct ccaaagcaga tcctggaccc 7800

 agcagcaagt gtaactggta gcaggaggca gctgagaact cgtaaggaaa 7850

 aggcccgtgc tctagaagac ctggttgact tcaaagagct cttctcagca 7900

 ccaggtcaca ctgaagagtc aatgactatt gacaaaaaca caaaaattcc 7950

 ctgcaaatct cccccaccag aactaacaga cactgccacg agcacaaaga 8000

 gatgccccaa gacacgtccc aggaaagaag taaaagagga gctctcagca 8050

 gttgagaggc tcacgcaaac atcagggcaa agcacacaca cacacaaaga 8100

 accagcaagc ggtgatgagg gcatcaaagt attgaagcaa cgtgcaaaga 8150

 agaaaccaaa cccagtagaa gaggaaccca gcaggagaag gccaagagca 8200

 cctaaggaaa aggcccaacc cctggaagac ctggccggct tcacagagct 8250

 ctctgaaaca tcaggtcaca ctcaggaatc actgactgct ggcaaagcca 8300

 ctaaaatacc ctgcgaatct cccccactag aagtggtaga caccacagca 8350

 agcacaaaga ggcatctcag gacacgtgtg cagaaggtac aagtaaaaga 8400

 agagccttca gcagtcaagt tcacacaaac atcaggggaa accacggatg 8450

 cagacaaaga accagcaggt gaagataaag gcatcaaagc attgaaggaa 8500

 tctgcaaaac agacaccggc tccagcagca agtgtaactg gcagcaggag 8550

 acggccaaga gcacccaggg aaagtgccca agccatagaa gacctagctg 8600

 gcttcaaaga cccagcagca ggtcacactg aagaatcaat gactgatgac 8650

 aaaaccacta aaataccctg caaatcatca ccagaactag aagacaccgc 8700

 aacaagctca aagagacggc ccaggacacg tgcccagaaa gtagaagtga 8750

 aggaggagct gttagcagtt ggcaagctca cacaaacctc aggggagacc 8800

 acgcacaccg acaaagagcc ggtaggtgag ggcaaaggca cgaaagcatt 8850

 taagcaacct gcaaagcgga acgtggacgc agaagatgta attggcagca 8900

 ggagacagcc aagagcacct aaggaaaagg cccaacccct ggaagacctg 8950

 gccagcttcc aagagctctc tcaaacacca ggccacactg aggaactggc 9000

 aaatggtgct gctgatagct ttacaagcgc tccaaagcaa acacctgaca 9050

 gtggaaaacc tctaaaaata tccagaagag ttcttcgggc ccctaaagta 9100

 gaacccgtgg gagacgtggt aagcaccaga gaccctgtaa aatcacaaag 9150

 caaaagcaac acttccctgc ccccactgcc cttcaagagg ggaggtggca 9200

 aagatggaag cgtcacggga accaagaggc tgcgctgcat gccagcacca 9250

 gaggaaattg tggaggagct gccagccagc aagaagcaga gggttgctcc 9300

 cagggcaaga ggcaaatcat ccgaacccgt ggtcatcatg aagagaagtt 9350

 tgaggacttc tgcaaaaaga attgaacctg cggaagagct gaacagcaac 9400

 gacatgaaaa ccaacaaaga ggaacacaaa ttacaagact cggtccctga 9450

 aaataaggga atatccctgc gctccagacg ccaagataag actgaggcag 9500

 aacagcaaat aactgaggtc tttgtattag cagaaagaat agaaataaac 9550

 agaaatgaaa agaagcccat gaagacctcc ccagagatgg acattcagaa 9600

 tccagatgat ggagcccgga aacccatacc tagagacaaa gtcactgaga 9650

 acaaaaggtg cttgaggtct gctagacaga atgagagctc ccagcctaag 9700

 gtggcagagg agagcggagg gcagaagagt gcgaaggttc tcatgcagaa 9750

 tcagaaaggg aaaggagaag caggaaattc agactccatg tgcctgagat 9800

 caagaaagac aaaaagccag cctgcagcaa gcactttgga gagcaaatct 9850

 gtgcagagag taacgcggag tgtcaagagg tgtgcagaaa atccaaagaa 9900

 ggctgaggac aatgtgtgtg tcaagaaaat aacaaccaga agtcataggg 9950

 acagtgaaga tatttgacag aaaaatcgaa ctgggaaaaa tataataaag 10000

 ttagttttgt gataagttct agtgcagttt ttgtcataaa ttacaagtga 10050

 attctgtaag taaggctgtc agtctgctta agggaagaaa actttggatt 10100

 tgctgggtct gaatcggctt cataaactcc actgggagca ctgctgggct 10150

 cctggactga gaatagttga acaccggggg ctttgtgaag gagtctgggc 10200

 caaggtttgc cctcagcttt gcagaatgaa gccttgaggt ctgtcaccac 10250

 ccacagccac cctacagcag ccttaactgt gacacttgcc acactgtgtc 10300

 gtcgtttgtt tgcctatgtt ctccagggca cggtggcagg aacaactatc 10350

 ctcgtctgtc ccaacactga gcaggcactc ggtaaacacg aatgaatgga 10400

 taagcgcacg gatgaatgga gcttacaaga tctgtctttc caatggccgg 10450

 gggcatttgg tccccaaatt aaggctattg gacatctgca caggacagtc 10500

 ctatttttga tgtcctttcc tttctgaaaa taaagttttg tgctttggag 10550

 aatgactcgt gagcacatct ttagggacca agagtgactt tctgtaagga 10600

 gtgactcgtg gcttgccttg gtctcttggg aatacttttc taactagggt 10650

 tgctctcacc tgagacattc tccacccgcg gaatctcagg gtcccaggct 10700

 gtgggccatc acgacctcaa actggctcct aatctccagc tttcctgtca 10750

 ttgaaagctt cggaagttta ctggctctgc tcccgcctgt tttctttctg 10800

 actctatctg gcagcccgat gccacccagt acaggaagtg acaccagtac 10850

 tctgtaaagc atcatcatcc ttggagagac tgagcactca gcaccttcag 10900

 ccacgatttc aggatcgctt ccttgtgagc cgctgcctcc gaaatctcct 10950

 ttgaagccca gacatctttc tccagcttca gacttgtaga tataactcgt 11000

 tcatcttcat ttactttcca ctttgccccc tgtcctctct gtgttcccca 11050

 aatcagagaa tagcccgcca tcccccagat cacctgtctg gattcctccc 11100

 cattcaccca ccttgccagg tgcaggtgag gatggtgcac cagacagggt 11150

 agctgtcccc caaaatgtgc cctgtgcggg cagtgccctg tctccacgtt 11200

 tgtttcccca gtgtctggcg gggagccagg tgacatcata aatacttgct 11250

 gaatgaatgc agaaatcagc ggtactgact tgtactatat tggctgccat 11300

 gatagggttc tcacagcgtc atccatgatc gtaagggaga atgacattct 11350

 gcttgaggga gggaatagaa aggggcaggg aggggacatc tgagggcttc 11400

 acagggctgc aaagggtaca gggattgcac cagggcagaa caggggaggg 11450

 tgttcaagga agagtggctc ttagcagagg cactttggaa ggtgtgaggc 11500

 ataaatgctt ccttctacgt aggccaacct caaaactttc agtaggaatg 11550

 ttgctatgat caagttgttc taacacttta gacttagtag taattatgaa 11600

 cctcacatag aaaaatttca tccagccata tgcctgtgga gtggaatatt 11650

 ctgtttagta gaaaaatcct ttagagttca gctctaacca gaaatcttgc 11700

 tgaagtatgt cagcaccttt tctcaccctg gtaagtacag tatttcaaga 11750

 gcacgctaag ggtggttttc attttacagg gctgttgatg atgggttaaa 11800

 aatgttcatt taagggctac ccccgtgttt aatagatgaa caccacttct 11850

 acacaaccct ccttggtact gggggaggga gagatctgac aaatactgcc 11900

 cattccccta ggctgactgg atttgagaac aaatacccac ccatttccac 11950

 catggtatgg taacttctct gagcttcagt ttccaagtga atttccatgt 12000

 aataggacat tcccattaaa tacaagctgt ttttactttt tcgcctccca 12050

 gggcctgtgc gatctggtcc cccagcctct cttgggcttt cttacactaa 12100

 ctctgtacct accatctcct gcctccctta ggcaggcacc tccaaccacc 12150

 acacactccc tgctgttttc cctgcctgga actttcccac cagccccacc 12200

 aagatcattt catccagtcc tgagctcagc ttaagggagg cttcttgcct 12250

 gtgggttccc tcacccccat gcctgtcctc caggctgggg caggttctta 12300

 gtttgcctgg aattgttctg tacctctttg tagcacgtag tgttgtgaaa 12350

 ctaagccact aattgagttt ctggctcccc tcctggggtt gtaagttttg 12400

 ttcattcatg agggccgact gtatttcctg gttactgtat cccagtgacc 12450

 agccacagga gatgtccaat aaagtatgtg atgaaatggt cttaaaaaaa 12500

 aaaaaaaaaa aaaaa 12515

<210> 2497
<211> 2000
<212> PRT
<213> Homo sapien

<400> 2497
 Met Trp Pro Thr Arg Arg Leu Val Thr Ile Lys Arg Ser Gly Val
   1               5                  10                  15

 Asp Gly Pro His Phe Pro Leu Ser Leu Ser Thr Cys Leu Phe Gly
                  20                  25                  30

 Arg Gly Ile Glu Cys Asp Ile Arg Ile Gln Leu Pro Val Val Ser
                  35                  40                  45

 Lys Gln His Cys Lys Ile Glu Ile His Glu Gln Glu Ala Ile Leu
                  50                  55                  60

 His Asn Phe Ser Ser Thr Asn Pro Thr Gln Val Asn Gly Ser Val
                  65                  70                  75

 Ile Asp Glu Pro Val Arg Leu Lys His Gly Asp Val Ile Thr Ile
                  80                  85                  90

 Ile Asp Arg Ser Phe Arg Tyr Glu Asn Glu Ser Leu Gln Asn Gly
                  95                 100                 105

 Arg Lys Ser Thr Glu Phe Pro Arg Lys Ile Arg Glu Gln Glu Pro
                 110                 115                 120

 Ala Arg Arg Val Ser Arg Ser Ser Phe Ser Ser Asp Pro Asp Glu
                 125                 130                 135

 Lys Ala Gln Asp Ser Lys Ala Tyr Ser Lys Ile Thr Glu Gly Lys
                 140                 145                 150

 Val Ser Gly Asn Pro Gln Val His Ile Lys Asn Val Lys Glu Asp
                 155                 160                 165

 Ser Thr Ala Asp Asp Ser Lys Asp Ser Val Ala Gln Gly Thr Thr
                 170                 175                 180

 Asn Val His Ser Ser Glu His Ala Gly Arg Asn Gly Arg Asn Ala
                 185                 190                 195

 Ala Asp Pro Ile Ser Gly Asp Phe Lys Glu Ile Ser Ser Val Lys
                 200                 205                 210

 Leu Val Ser Arg Tyr Gly Glu Leu Lys Ser Val Pro Thr Thr Gln
                 215                 220                 225

 Cys Leu Asp Asn Ser Lys Lys Asn Glu Ser Pro Phe Trp Lys Leu
                 230                 235                 240

 Tyr Glu Ser Val Lys Lys Glu Leu Asp Val Lys Ser Gln Lys Glu
                 245                 250                 255

 Asn Val Leu Gln Tyr Cys Arg Lys Ser Gly Leu Gln Thr Asp Tyr
                 260                 265                 270

 Ala Thr Glu Lys Glu Ser Ala Asp Gly Leu Gln Gly Glu Thr Gln
                 275                 280                 285

 Leu Leu Val Ser Arg Lys Ser Arg Pro Lys Ser Gly Gly Ser Gly
                 290                 295                 300

 His Ala Val Ala Glu Pro Ala Ser Pro Glu Gln Glu Leu Asp Gln
                 305                 310                 315

 Asn Lys Gly Lys Gly Arg Asp Val Glu Ser Val Gln Thr Pro Ser
                 320                 325                 330

 Lys Ala Val Gly Ala Ser Phe Pro Leu Tyr Glu Pro Ala Lys Met
                 335                 340                 345

 Lys Thr Pro Val Gln Tyr Ser Gln Gln Gln Asn Ser Pro Gln Lys
                 350                 355                 360

 His Lys Asn Lys Asp Leu Tyr Thr Thr Gly Arg Arg Glu Ser Val
                 365                 370                 375

 Asn Leu Gly Lys Ser Glu Gly Phe Lys Ala Gly Asp Lys Thr Leu
                 380                 385                 390

 Thr Pro Arg Lys Leu Ser Thr Arg Asn Arg Thr Pro Ala Lys Val
                 395                 400                 405

 Glu Asp Ala Ala Asp Ser Ala Thr Lys Pro Glu Asn Leu Ser Ser
                 410                 415                 420

 Lys Thr Arg Gly Ser Ile Pro Thr Asp Val Glu Val Leu Pro Thr
                 425                 430                 435

 Glu Thr Glu Ile His Asn Glu Pro Phe Leu Thr Leu Trp Leu Thr
                 440                 445                 450

 Gln Val Glu Arg Lys Ile Gln Lys Asp Ser Leu Ser Lys Pro Glu
                 455                 460                 465

 Lys Leu Gly Thr Thr Ala Gly Gln Met Cys Ser Gly Leu Pro Gly
                 470                 475                 480

 Leu Ser Ser Val Asp Ile Asn Asn Phe Gly Asp Ser Ile Asn Glu
                 485                 490                 495

 Ser Glu Gly Ile Pro Leu Lys Arg Arg Arg Val Ser Phe Gly Gly
                 500                 505                 510

 His Leu Arg Pro Glu Leu Phe Asp Glu Asn Leu Pro Pro Asn Thr
                 515                 520                 525

 Pro Leu Lys Arg Gly Glu Ala Pro Thr Lys Arg Lys Ser Leu Val
                 530                 535                 540

 Met His Thr Pro Pro Val Leu Lys Lys Ile Ile Lys Glu Gln Pro
                 545                 550                 555

 Gln Pro Ser Gly Lys Gln Glu Ser Gly Ser Glu Ile His Val Glu
                 560                 565                 570

 Val Lys Ala Gln Ser Leu Val Ile Ser Pro Pro Ala Pro Ser Pro
                 575                 580                 585

 Arg Lys Thr Pro Val Ala Ser Asp Gln Arg Arg Arg Ser Cys Lys
                 590                 595                 600

 Thr Ala Pro Ala Ser Ser Ser Lys Ser Gln Thr Glu Val Pro Lys
                 605                 610                 615

 Arg Gly Gly Glu Arg Val Ala Thr Cys Leu Gln Lys Arg Val Ser
                 620                 625                 630

 Ile Ser Arg Ser Gln His Asp Ile Leu Gln Met Ile Cys Ser Lys
                 635                 640                 645

 Arg Arg Ser Gly Ala Ser Glu Ala Asn Leu Ile Val Ala Lys Ser
                 650                 655                 660

 Trp Ala Asp Val Val Lys Leu Gly Ala Lys Gln Thr Gln Thr Lys
                 665                 670                 675

 Val Ile Lys His Gly Pro Gln Arg Ser Met Asn Lys Arg Gln Arg
                 680                 685                 690

 Arg Pro Ala Thr Pro Lys Lys Pro Val Gly Glu Val His Ser Gln
                 695                 700                 705

 Phe Ser Thr Gly His Ala Asn Ser Pro Cys Thr Ile Ile Ile Gly
                 710                 715                 720

 Lys Ala His Thr Glu Lys Val His Val Pro Ala Arg Pro Tyr Arg
                 725                 730                 735

 Val Leu Asn Asn Phe Ile Ser Asn Gln Lys Met Asp Phe Lys Glu
                 740                 745                 750

 Asp Leu Ser Gly Ile Ala Glu Met Phe Lys Thr Pro Val Lys Glu
                 755                 760                 765

 Gln Pro Gln Leu Thr Ser Thr Cys His Ile Ala Ile Ser Asn Ser
                 770                 775                 780

 Glu Asn Leu Leu Gly Lys Gln Phe Gln Gly Thr Asp Ser Gly Glu
                 785                 790                 795

 Glu Pro Leu Leu Pro Thr Ser Glu Ser Phe Gly Gly Asn Val Phe
                 800                 805                 810

 Phe Ser Ala Gln Asn Ala Ala Lys Gln Pro Ser Asp Lys Cys Ser
                 815                 820                 825

 Ala Ser Pro Pro Leu Arg Arg Gln Cys Ile Arg Glu Asn Gly Asn
                 830                 835                 840

 Val Ala Lys Thr Pro Arg Asn Thr Tyr Lys Met Thr Ser Leu Glu
                 845                 850                 855

 Thr Lys Thr Ser Asp Thr Glu Thr Glu Pro Ser Lys Thr Val Ser
                 860                 865                 870

 Thr Val Asn Arg Ser Gly Arg Ser Thr Glu Phe Arg Asn Ile Gln
                 875                 880                 885

 Lys Leu Pro Val Glu Ser Lys Ser Glu Glu Thr Asn Thr Glu Ile
                 890                 895                 900

 Val Glu Cys Ile Leu Lys Arg Gly Gln Lys Ala Thr Leu Leu Gln
                 905                 910                 915

 Gln Arg Arg Glu Gly Glu Met Lys Glu Ile Glu Arg Pro Phe Glu
                 920                 925                 930

 Thr Tyr Lys Glu Asn Ile Glu Leu Lys Glu Asn Asp Glu Lys Met
                 935                 940                 945

 Lys Ala Met Lys Arg Ser Arg Thr Trp Gly Gln Lys Cys Ala Pro
                 950                 955                 960

 Met Ser Asp Leu Thr Asp Leu Lys Ser Leu Pro Asp Thr Glu Leu
                 965                 970                 975

 Met Lys Asp Thr Ala Arg Gly Gln Asn Leu Leu Gln Thr Gln Asp
                 980                 985                 990

 His Ala Lys Ala Pro Lys Ser Glu Lys Gly Lys Ile Thr Lys Met
                 995                1000                1005

 Pro Cys Gln Ser Leu Gln Pro Glu Pro Ile Asn Thr Pro Thr His
                1010                1015                1020

 Thr Lys Gln Gln Leu Lys Ala Ser Leu Gly Lys Val Gly Val Lys
                1025                1030                1035

 Glu Glu Leu Leu Ala Val Gly Lys Phe Thr Arg Thr Ser Gly Glu
                1040                1045                1050

 Thr Thr His Thr His Arg Glu Pro Ala Gly Asp Gly Lys Ser Ile
                1055                1060                1065

 Arg Thr Phe Lys Glu Ser Pro Lys Gln Ile Leu Asp Pro Ala Ala
                1070                1075                1080

 Arg Val Thr Gly Met Lys Lys Trp Pro Arg Thr Pro Lys Glu Glu
                1085                1090                1095

 Ala Gln Ser Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln
                1100                1105                1110

 Thr Pro Gly Pro Ser Glu Glu Ser Met Thr Asp Glu Lys Thr Thr
                1115                1120                1125

 Lys Ile Ala Cys Lys Ser Pro Pro Pro Glu Ser Val Asp Thr Pro
                1130                1135                1140

 Thr Ser Thr Lys Gln Trp Pro Lys Arg Ser Leu Arg Lys Ala Asp
                1145                1150                1155

 Val Glu Glu Glu Phe Leu Ala Leu Arg Lys Leu Thr Pro Ser Ala
                1160                1165                1170

 Gly Lys Ala Met Leu Thr Pro Lys Pro Ala Gly Gly Asp Glu Lys
                1175                1180                1185

 Asp Ile Lys Ala Phe Met Gly Thr Pro Val Gln Lys Leu Asp Leu
                1190                1195                1200

 Ala Gly Thr Leu Pro Gly Ser Lys Arg Gln Leu Gln Thr Pro Lys
                1205                1210                1215

 Glu Lys Ala Gln Ala Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu
                1220                1225                1230

 Phe Gln Thr Pro Gly His Thr Glu Glu Leu Val Ala Ala Gly Lys
                1235                1240                1245

 Thr Thr Lys Ile Pro Cys Asp Ser Pro Gln Ser Asp Pro Val Asp
                1250                1255                1260

 Thr Pro Thr Ser Thr Lys Gln Arg Pro Lys Arg Ser Ile Arg Lys
                1265                1270                1275

 Ala Asp Val Glu Gly Glu Leu Leu Ala Cys Arg Asn Leu Met Pro
                1280                1285                1290

 Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ser Val Gly Glu
                1295                1300                1305

 Glu Lys Asp Ile Ile Ile Phe Val Gly Thr Pro Val Gln Lys Leu
                1310                1315                1320

 Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Pro Gln Thr
                1325                1330                1335

 Pro Lys Glu Glu Ala Gln Ala Leu Glu Asp Leu Thr Gly Phe Lys
                1340                1345                1350

 Glu Leu Phe Gln Thr Pro Gly His Thr Glu Glu Ala Val Ala Ala
                1355                1360                1365

 Gly Lys Thr Thr Lys Met Pro Cys Glu Ser Ser Pro Pro Glu Ser
                1370                1375                1380

 Ala Asp Thr Pro Thr Ser Thr Arg Arg Gln Pro Lys Thr Pro Leu
                1385                1390                1395

 Glu Lys Arg Asp Val Gln Lys Glu Leu Ser Ala Leu Lys Lys Leu
                1400                1405                1410

 Thr Gln Thr Ser Gly Glu Thr Thr His Thr Asp Lys Val Pro Gly
                1415                1420                1425

 Gly Glu Asp Lys Ser Ile Asn Ala Phe Arg Glu Thr Ala Lys Gln
                1430                1435                1440

 Lys Leu Asp Pro Ala Ala Ser Val Thr Gly Ser Lys Arg His Pro
                1445                1450                1455

 Lys Thr Lys Glu Lys Ala Gln Pro Leu Glu Asp Leu Ala Gly Trp
                1460                1465                1470

 Lys Glu Leu Phe Gln Thr Pro Val Cys Thr Asp Lys Pro Thr Thr
                1475                1480                1485

 His Glu Lys Thr Thr Lys Ile Ala Cys Arg Ser Gln Pro Asp Pro
                1490                1495                1500

 Val Asp Thr Pro Thr Ser Ser Lys Pro Gln Ser Lys Arg Ser Leu
                1505                1510                1515

 Arg Lys Val Asp Val Glu Glu Glu Phe Phe Ala Leu Arg Lys Arg
                1520                1525                1530

 Thr Pro Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ala Val
                1535                1540                1545

 Ser Gly Glu Lys Asn Ile Tyr Ala Phe Met Gly Thr Pro Val Gln
                1550                1555                1560

 Lys Leu Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Leu
                1565                1570                1575

 Gln Thr Pro Lys Glu Lys Ala Gln Ala Leu Glu Asp Leu Ala Gly
                1580                1585                1590

 Phe Lys Glu Leu Phe Gln Thr Arg Gly His Thr Glu Glu Ser Met
                1595                1600                1605

 Thr Asn Asp Lys Thr Ala Lys Val Ala Cys Lys Ser Ser Gln Pro
                1610                1615                1620

 Asp Leu Asp Lys Asn Pro Ala Ser Ser Lys Arg Arg Leu Lys Thr
                1625                1630                1635

 Ser Leu Gly Lys Val Gly Val Lys Glu Glu Leu Leu Ala Val Gly
                1640                1645                1650

 Lys Leu Thr Gln Thr Ser Gly Glu Thr Thr His Thr His Thr Glu
                1655                1660                1665

 Pro Thr Gly Asp Gly Lys Ser Met Lys Ala Phe Met Glu Ser Pro
                1670                1675                1680

 Lys Gln Ile Leu Asp Ser Ala Ala Ser Leu Thr Gly Ser Lys Arg
                1685                1690                1695

 Gln Leu Arg Thr Pro Lys Gly Lys Ser Glu Val Pro Glu Asp Leu
                1700                1705                1710

 Ala Gly Phe Ile Glu Leu Phe Gln Thr Pro Ser His Thr Lys Glu
                1715                1720                1725

 Ser Met Thr Asn Glu Lys Thr Thr Lys Val Ser Tyr Arg Ala Ser
                1730                1735                1740

 Gln Pro Asp Leu Val Asp Thr Pro Thr Ser Ser Lys Pro Gln Pro
                1745                1750                1755

 Lys Arg Ser Leu Arg Lys Ala Asp Thr Glu Glu Glu Phe Leu Ala
                1760                1765                1770

 Phe Arg Lys Gln Thr Pro Ser Ala Gly Lys Ala Met His Thr Pro
                1775                1780                1785

 Lys Pro Ala Val Gly Glu Glu Lys Asp Ile Asn Thr Phe Leu Gly
                1790                1795                1800

 Thr Pro Val Gln Lys Leu Asp Gln Pro Gly Asn Leu Pro Gly Ser
                1805                1810                1815

 Asn Arg Arg Leu Gln Thr Arg Lys Glu Lys Ala Gln Ala Leu Glu
                1820                1825                1830

 Glu Leu Thr Gly Phe Arg Glu Leu Phe Gln Thr Pro Cys Thr Asp
                1835                1840                1845

 Asn Pro Thr Ala Asp Glu Lys Thr Thr Lys Lys Ile Leu Cys Lys
                1850                1855                1860

 Ser Pro Gln Ser Asp Pro Ala Asp Thr Pro Thr Asn Thr Lys Gln
                1865                1870                1875

 Arg Pro Lys Arg Ser Leu Lys Lys Ala Asp Val Glu Glu Glu Phe
                1880                1885                1890

 Leu Ala Phe Arg Lys Leu Thr Pro Ser Ala Gly Lys Ala Met His
                1895                1900                1905

 Thr Pro Lys Ala Ala Val Gly Glu Glu Lys Asp Ile Asn Thr Phe
                1910                1915                1920

 Val Gly Thr Pro Val Glu Lys Leu Asp Leu Leu Gly Asn Leu Pro
                1925                1930                1935

 Gly Ser Lys Arg Arg Pro Gln Thr Pro Lys Glu Lys Ala Lys Ala
                1940                1945                1950

 Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr Pro Gly
                1955                1960                1965

 His Thr Glu Glu Ser Met Thr Asp Asp Lys Ile Thr Glu Val Ser
                1970                1975                1980

 Cys Lys Ser Pro Gln Pro Asp Pro Val Lys Thr Pro Thr Ser Ser
                1985                1990                1995

 Lys Gln Arg Leu Lys
                2000

<210> 2498
<211> 12515
<212> DNA
<213> Homo sapien

<400> 2498
 ctaccgggcg gaggtgagcg cggcgccggc tcctcctgcg gcggactttg 50

 ggtgcgactt gacgagcggt ggttcgacaa gtggccttgc gggccggatc 100

 gtcccagtgg aagagttgta aatttgcttc tggccttccc ctacggatta 150

 tacctggcct tcccctacgg attatactca acttactgtt tagaaaatgt 200

 ggcccacgag acgcctggtt actatcaaaa ggagcggggt cgacggtccc 250

 cactttcccc tgagcctcag cacctgcttg tttggaaggg gtattgaatg 300

 tgacatccgt atccagcttc ctgttgtgtc aaaacaacat tgcaaaattg 350

 aaatccatga gcaggaggca atattacata atttcagttc cacaaatcca 400

 acacaagtaa atgggtctgt tattgatgag cctgtacggc taaaacatgg 450

 agatgtaata actattattg atcgttcctt caggtatgaa aatgaaagtc 500

 ttcagaatgg aaggaagtca actgaatttc caagaaaaat acgtgaacag 550

 gagccagcac gtcgtgtctc aagatctagc ttctcttctg accctgatga 600

 gaaagctcaa gattccaagg cctattcaaa aatcactgaa ggaaaagttt 650

 caggaaatcc tcaggtacat atcaagaatg tcaaagaaga cagtaccgca 700

 gatgactcaa aagacagtgt tgctcaggga acaactaatg ttcattcctc 750

 agaacatgct ggacgtaatg gcagaaatgc agctgatccc atttctgggg 800

 attttaaaga aatttccagc gttaaattag tgagccgtta tggagaattg 850

 aagtctgttc ccactacaca atgtcttgac aatagcaaaa aaaatgaatc 900

 tcccttttgg aagctttatg agtcagtgaa gaaagagttg gatgtaaaat 950

 cacaaaaaga aaatgtccta cagtattgta gaaaatctgg attacaaact 1000

 gattacgcaa cagagaaaga aagtgctgat ggtttacagg gggagaccca 1050

 actgttggtc tcgcgtaagt caagaccaaa atctggtggg agcggccacg 1100

 ctgtggcaga gcctgcttca cctgaacaag agcttgacca gaacaagggg 1150

 aagggaagag acgtggagtc tgttcagact cccagcaagg ctgtgggcgc 1200

 cagctttcct ctctatgagc cggctaaaat gaagacccct gtacaatatt 1250

 cacagcaaca aaattctcca caaaaacata agaacaaaga cctgtatact 1300

 actggtagaa gagaatctgt gaatctgggt aaaagtgaag gcttcaaggc 1350

 tggtgataaa actcttactc ccaggaagct ttcaactaga aatcgaacac 1400

 cagctaaagt tgaagatgca gctgactctg ccactaagcc agaaaatctc 1450

 tcttccaaaa ccagaggaag tattcctaca gatgtggaag ttctgcctac 1500

 ggaaactgaa attcacaatg agccattttt aactctgtgg ctcactcaag 1550

 ttgagaggaa gatccaaaag gattccctca gcaagcctga gaaattgggc 1600

 actacagctg gacagatgtg ctctgggtta cctggtctta gttcagttga 1650

 tatcaacaac tttggtgatt ccattaatga gagtgaggga atacctttga 1700

 aaagaaggcg tgtgtccttt ggtgggcacc taagacctga actatttgat 1750

 gaaaacttgc ctcctaatac gcctctcaaa aggggagaag ccccaaccaa 1800

 aagaaagtct ctggtaatgc acactccacc tgtcctgaag aaaatcatca 1850

 aggaacagcc tcaaccatca ggaaaacaag agtcaggttc agaaatccat 1900

 gtggaagtga aggcacaaag cttggttata agccctccag ctcctagtcc 1950

 taggaaaact ccagttgcca gtgatcaacg ccgtaggtcc tgcaaaacag 2000

 cccctgcttc cagcagcaaa tctcagacag aggttcctaa gagaggagga 2050

 gaaagagtgg caacctgcct tcaaaagaga gtgtctatca gccgaagtca 2100

 acatgatatt ttacagatga tatgttccaa aagaagaagt ggtgcttcgg 2150

 aagcaaatct gattgttgca aaatcatggg cagatgtagt aaaacttggt 2200

 gcaaaacaaa cacaaactaa agtcataaaa catggtcctc aaaggtcaat 2250

 gaacaaaagg caaagaagac ctgctactcc aaagaagcct gtgggcgaag 2300

 ttcacagtca atttagtaca ggccacgcaa actctccttg taccataata 2350

 atagggaaag ctcatactga aaaagtacat gtgcctgctc gaccctacag 2400

 agtgctcaac aacttcattt ccaaccaaaa aatggacttt aaggaagatc 2450

 tttcaggaat agctgaaatg ttcaagaccc cagtgaagga gcaaccgcag 2500

 ttgacaagca catgtcacat cgctatttca aattcagaga atttgcttgg 2550

 aaaacagttt caaggaactg attcaggaga agaacctctg ctccccacct 2600

 cagagagttt tggaggaaat gtgttcttca gtgcacagaa tgcagcaaaa 2650

 cagccatctg ataaatgctc tgcaagccct cccttaagac ggcagtgtat 2700

 tagagaaaat ggaaacgtag caaaaacgcc caggaacacc tacaaaatga 2750

 cttctctgga gacaaaaact tcagatactg agacagagcc ttcaaaaaca 2800

 gtatccactg taaacaggtc aggaaggtct acagagttca ggaatataca 2850

 gaagctacct gtggaaagta agagtgaaga aacaaataca gaaattgttg 2900

 agtgcatcct aaaaagaggt cagaaggcaa cactactaca acaaaggaga 2950

 gaaggagaga tgaaggaaat agaaagacct tttgagacat ataaggaaaa 3000

 tattgaatta aaagaaaacg atgaaaagat gaaagcaatg aagagatcaa 3050

 gaacttgggg gcagaaatgt gcaccaatgt ctgacctgac agacctcaag 3100

 agcttgcctg atacagaact catgaaagac acggcacgtg gccagaatct 3150

 cctccaaacc caagatcatg ccaaggcacc aaagagtgag aaaggcaaaa 3200

 tcactaaaat gccctgccag tcattacaac cagaaccaat aaacacccca 3250

 acacacacaa aacaacagtt gaaggcatcc ctggggaaag taggtgtgaa 3300

 agaagagctc ctagcagtcg gcaagttcac acggacgtca ggggagacca 3350

 cgcacacgca cagagagcca gcaggagatg gcaagagcat cagaacgttt 3400

 aaggagtctc caaagcagat cctggaccca gcagcccgtg taactggaat 3450

 gaagaagtgg ccaagaacgc ctaaggaaga ggcccagtca ctagaagacc 3500

 tggctggctt caaagagctc ttccagacac caggtccctc tgaggaatca 3550

 atgactgatg agaaaactac caaaatagcc tgcaaatctc caccaccaga 3600

 atcagtggac actccaacaa gcacaaagca atggcctaag agaagtctca 3650

 ggaaagcaga tgtagaggaa gaattcttag cactcaggaa actaacacca 3700

 tcagcaggga aagccatgct tacgcccaaa ccagcaggag gtgatgagaa 3750

 agacattaaa gcatttatgg gaactccagt gcagaaactg gacctggcag 3800

 gaactttacc tggcagcaaa agacagctac agactcctaa ggaaaaggcc 3850

 caggctctag aagacctggc tggctttaaa gagctcttcc agactcctgg 3900

 tcacaccgag gaattagtgg ctgctggtaa aaccactaaa ataccctgcg 3950

 actctccaca gtcagaccca gtggacaccc caacaagcac aaagcaacga 4000

 cccaagagaa gtatcaggaa agcagatgta gagggagaac tcttagcgtg 4050

 caggaatcta atgccatcag caggcaaagc catgcacacg cctaaaccat 4100

 cagtaggtga agagaaagac atcatcatat ttgtgggaac tccagtgcag 4150

 aaactggacc tgacagagaa cttaaccggc agcaagagac ggccacaaac 4200

 tcctaaggaa gaggcccagg ctctggaaga cctgactggc tttaaagagc 4250

 tcttccagac ccctggtcat actgaagaag cagtggctgc tggcaaaact 4300

 actaaaatgc cctgcgaatc ttctccacca gaatcagcag acaccccaac 4350

 aagcacaaga aggcagccca agacaccttt ggagaaaagg gacgtacaga 4400

 aggagctctc agccctgaag aagctcacac agacatcagg ggaaaccaca 4450

 cacacagata aagtaccagg aggtgaggat aaaagcatca acgcgtttag 4500

 ggaaactgca aaacagaaac tggacccagc agcaagtgta actggtagca 4550

 agaggcaccc aaaaactaag gaaaaggccc aacccctaga agacctggct 4600

 ggctggaaag agctcttcca gacaccagta tgcactgaca agcccacgac 4650

 tcacgagaaa actaccaaaa tagcctgcag atcacaacca gacccagtgg 4700

 acacaccaac aagctccaag ccacagtcca agagaagtct caggaaagtg 4750

 gacgtagaag aagaattctt cgcactcagg aaacgaacac catcagcagg 4800

 caaagccatg cacacaccca aaccagcagt aagtggtgag aaaaacatct 4850

 acgcatttat gggaactcca gtgcagaaac tggacctgac agagaactta 4900

 actggcagca agagacggct acaaactcct aaggaaaagg cccaggctct 4950

 agaagacctg gctggcttta aagagctctt ccagacacga ggtcacactg 5000

 aggaatcaat gactaacgat aaaactgcca aagtagcctg caaatcttca 5050

 caaccagacc tagacaaaaa cccagcaagc tccaagcgac ggctcaagac 5100

 atccctgggg aaagtgggcg tgaaagaaga gctcctagca gttggcaagc 5150

 tcacacagac atcaggagag actacacaca cacacacaga gccaacagga 5200

 gatggtaaga gcatgaaagc atttatggag tctccaaagc agatcttaga 5250

 ctcagcagca agtctaactg gcagcaagag gcagctgaga actcctaagg 5300

 gaaagtctga agtccctgaa gacctggccg gcttcatcga gctcttccag 5350

 acaccaagtc acactaagga atcaatgact aatgaaaaaa ctaccaaagt 5400

 atcctacaga gcttcacagc cagacctagt ggacacccca acaagctcca 5450

 agccacagcc caagagaagt ctcaggaaag cagacactga agaagaattt 5500

 ttagcattta ggaaacaaac gccatcagca ggcaaagcca tgcacacacc 5550

 caaaccagca gtaggtgaag agaaagacat caacacgttt ttgggaactc 5600

 cagtgcagaa actggaccag ccaggaaatt tacctggcag caatagacgg 5650

 ctacaaactc gtaaggaaaa ggcccaggct ctagaagaac tgactggctt 5700

 cagagagctt ttccagacac catgcactga taaccccaca gctgatgaga 5750

 aaactaccaa aaaaatactc tgcaaatctc cgcaatcaga cccagcggac 5800

 accccaacaa acacaaagca acggcccaag agaagcctca agaaagcaga 5850

 cgtagaggaa gaatttttag cattcaggaa actaacacca tcagcaggca 5900

 aagccatgca cacgcctaaa gcagcagtag gtgaagagaa agacatcaac 5950

 acatttgtgg ggactccagt ggagaaactg gacctgctag gaaatttacc 6000

 tggcagcaag agacggccac aaactcctaa agaaaaggcc aaggctctag 6050

 aagatctggc tggcttcaaa gagctcttcc agacaccagg tcacactgag 6100

 gaatcaatga ccgatgacaa aatcacagaa gtatcctgca aatctccaca 6150

 accagaccca gtcaaaaccc caacaagctc caagcaacga ctcaagatat 6200

 ccttggggaa agtaggtgtg aaagaagagg tcctaccagt cggcaagctc 6250

 acacagacgt cagggaagac cacacagaca cacagagaga cagcaggaga 6300

 tggaaagagc atcaaagcgt ttaaggaatc tgcaaagcag atgctggacc 6350

 cagcaaacta tggaactggg atggagaggt ggccaagaac acctaaggaa 6400

 gaggcccaat cactagaaga cctggccggc ttcaaagagc tcttccagac 6450

 accagaccac actgaggaat caacaactga tgacaaaact accaaaatag 6500

 cctgcaaatc tccaccacca gaatcaatgg acactccaac aagcacaagg 6550

 aggcggccca aaacaccttt ggggaaaagg gatatagtgg aagagctctc 6600

 agccctgaag cagctcacac agaccacaca cacagacaaa gtaccaggag 6650

 atgaggataa aggcatcaac gtgttcaggg aaactgcaaa acagaaactg 6700

 gacccagcag caagtgtaac tggtagcaag aggcagccaa gaactcctaa 6750

 gggaaaagcc caacccctag aagacttggc tggcttgaaa gagctcttcc 6800

 agacaccagt atgcactgac aagcccacga ctcacgagaa aactaccaaa 6850

 atagcctgca gatctccaca accagaccca gtgggtaccc caacaatctt 6900

 caagccacag tccaagagaa gtctcaggaa agcagacgta gaggaagaat 6950

 ccttagcact caggaaacga acaccatcag tagggaaagc tatggacaca 7000

 cccaaaccag caggaggtga tgagaaagac atgaaagcat ttatgggaac 7050

 tccagtgcag aaattggacc tgccaggaaa tttacctggc agcaaaagat 7100

 ggccacaaac tcctaaggaa aaggcccagg ctctagaaga cctggctggc 7150

 ttcaaagagc tcttccagac accaggcact gacaagccca cgactgatga 7200

 gaaaactacc aaaatagcct gcaaatctcc acaaccagac ccagtggaca 7250

 ccccagcaag cacaaagcaa cggcccaaga gaaacctcag gaaagcagac 7300

 gtagaggaag aatttttagc actcaggaaa cgaacaccat cagcaggcaa 7350

 agccatggac accccaaaac cagcagtaag tgatgagaaa aatatcaaca 7400

 catttgtgga aactccagtg cagaaactgg acctgctagg aaatttacct 7450

 ggcagcaaga gacagccaca gactcctaag gaaaaggctg aggctctaga 7500

 ggacctggtt ggcttcaaag aactcttcca gacaccaggt cacactgagg 7550

 aatcaatgac tgatgacaaa atcacagaag tatcctgtaa atctccacag 7600

 ccagagtcat tcaaaacctc aagaagctcc aagcaaaggc tcaagatacc 7650

 cctggtgaaa gtggacatga aagaagagcc cctagcagtc agcaagctca 7700

 cacggacatc aggggagact acgcaaacac acacagagcc aacaggagat 7750

 agtaagagca tcaaagcgtt taaggagtct ccaaagcaga tcctggaccc 7800

 agcagcaagt gtaactggta gcaggaggca gctgagaact cgtaaggaaa 7850

 aggcccgtgc tctagaagac ctggttgact tcaaagagct cttctcagca 7900

 ccaggtcaca ctgaagagtc aatgactatt gacaaaaaca caaaaattcc 7950

 ctgcaaatct cccccaccag aactaacaga cactgccacg agcacaaaga 8000

 gatgccccaa gacacgtccc aggaaagaag taaaagagga gctctcagca 8050

 gttgagaggc tcacgcaaac atcagggcaa agcacacaca cacacaaaga 8100

 accagcaagc ggtgatgagg gcatcaaagt attgaagcaa cgtgcaaaga 8150

 agaaaccaaa cccagtagaa gaggaaccca gcaggagaag gccaagagca 8200

 cctaaggaaa aggcccaacc cctggaagac ctggccggct tcacagagct 8250

 ctctgaaaca tcaggtcaca ctcaggaatc actgactgct ggcaaagcca 8300

 ctaaaatacc ctgcgaatct cccccactag aagtggtaga caccacagca 8350

 agcacaaaga ggcatctcag gacacgtgtg cagaaggtac aagtaaaaga 8400

 agagccttca gcagtcaagt tcacacaaac atcaggggaa accacggatg 8450

 cagacaaaga accagcaggt gaagataaag gcatcaaagc attgaaggaa 8500

 tctgcaaaac agacaccggc tccagcagca agtgtaactg gcagcaggag 8550

 acggccaaga gcacccaggg aaagtgccca agccatagaa gacctagctg 8600

 gcttcaaaga cccagcagca ggtcacactg aagaatcaat gactgatgac 8650

 aaaaccacta aaataccctg caaatcatca ccagaactag aagacaccgc 8700

 aacaagctca aagagacggc ccaggacacg tgcccagaaa gtagaagtga 8750

 aggaggagct gttagcagtt ggcaagctca cacaaacctc aggggagacc 8800

 acgcacaccg acaaagagcc ggtaggtgag ggcaaaggca cgaaagcatt 8850

 taagcaacct gcaaagcgga acgtggacgc agaagatgta attggcagca 8900

 ggagacagcc aagagcacct aaggaaaagg cccaacccct ggaagacctg 8950

 gccagcttcc aagagctctc tcaaacacca ggccacactg aggaactggc 9000

 aaatggtgct gctgatagct ttacaagcgc tccaaagcaa acacctgaca 9050

 gtggaaaacc tctaaaaata tccagaagag ttcttcgggc ccctaaagta 9100

 gaacccgtgg gagacgtggt aagcaccaga gaccctgtaa aatcacaaag 9150

 caaaagcaac acttccctgc ccccactgcc cttcaagagg ggaggtggca 9200

 aagatggaag cgtcacggga accaagaggc tgcgctgcat gccagcacca 9250

 gaggaaattg tggaggagct gccagccagc aagaagcaga gggttgctcc 9300

 cagggcaaga ggcaaatcat ccgaacccgt ggtcatcatg aagagaagtt 9350

 tgaggacttc tgcaaaaaga attgaacctg cggaagagct gaacagcaac 9400

 gacatgaaaa ccaacaaaga ggaacacaaa ttacaagact cggtccctga 9450

 aaataaggga atatccctgc gctccagacg ccaagataag actgaggcag 9500

 aacagcaaat aactgaggtc tttgtattag cagaaagaat agaaataaac 9550

 agaaatgaaa agaagcccat gaagacctcc ccagagatgg acattcagaa 9600

 tccagatgat ggagcccgga aacccatacc tagagacaaa gtcactgaga 9650

 acaaaaggtg cttgaggtct gctagacaga atgagagctc ccagcctaag 9700

 gtggcagagg agagcggagg gcagaagagt gcgaaggttc tcatgcagaa 9750

 tcagaaaggg aaaggagaag caggaaattc agactccatg tgcctgagat 9800

 caagaaagac aaaaagccag cctgcagcaa gcactttgga gagcaaatct 9850

 gtgcagagag taacgcggag tgtcaagagg tgtgcagaaa atccaaagaa 9900

 ggctgaggac aatgtgtgtg tcaagaaaat aacaaccaga agtcataggg 9950

 acagtgaaga tatttgacag aaaaatcgaa ctgggaaaaa tataataaag 10000

 ttagttttgt gataagttct agtgcagttt ttgtcataaa ttacaagtga 10050

 attctgtaag taaggctgtc agtctgctta agggaagaaa actttggatt 10100

 tgctgggtct gaatcggctt cataaactcc actgggagca ctgctgggct 10150

 cctggactga gaatagttga acaccggggg ctttgtgaag gagtctgggc 10200

 caaggtttgc cctcagcttt gcagaatgaa gccttgaggt ctgtcaccac 10250

 ccacagccac cctacagcag ccttaactgt gacacttgcc acactgtgtc 10300

 gtcgtttgtt tgcctatgtt ctccagggca cggtggcagg aacaactatc 10350

 ctcgtctgtc ccaacactga gcaggcactc ggtaaacacg aatgaatgga 10400

 taagcgcacg gatgaatgga gcttacaaga tctgtctttc caatggccgg 10450

 gggcatttgg tccccaaatt aaggctattg gacatctgca caggacagtc 10500

 ctatttttga tgtcctttcc tttctgaaaa taaagttttg tgctttggag 10550

 aatgactcgt gagcacatct ttagggacca agagtgactt tctgtaagga 10600

 gtgactcgtg gcttgccttg gtctcttggg aatacttttc taactagggt 10650

 tgctctcacc tgagacattc tccacccgcg gaatctcagg gtcccaggct 10700

 gtgggccatc acgacctcaa actggctcct aatctccagc tttcctgtca 10750

 ttgaaagctt cggaagttta ctggctctgc tcccgcctgt tttctttctg 10800

 actctatctg gcagcccgat gccacccagt acaggaagtg acaccagtac 10850

 tctgtaaagc atcatcatcc ttggagagac tgagcactca gcaccttcag 10900

 ccacgatttc aggatcgctt ccttgtgagc cgctgcctcc gaaatctcct 10950

 ttgaagccca gacatctttc tccagcttca gacttgtaga tataactcgt 11000

 tcatcttcat ttactttcca ctttgccccc tgtcctctct gtgttcccca 11050

 aatcagagaa tagcccgcca tcccccagat cacctgtctg gattcctccc 11100

 cattcaccca ccttgccagg tgcaggtgag gatggtgcac cagacagggt 11150

 agctgtcccc caaaatgtgc cctgtgcggg cagtgccctg tctccacgtt 11200

 tgtttcccca gtgtctggcg gggagccagg tgacatcata aatacttgct 11250

 gaatgaatgc agaaatcagc ggtactgact tgtactatat tggctgccat 11300

 gatagggttc tcacagcgtc atccatgatc gtaagggaga atgacattct 11350

 gcttgaggga gggaatagaa aggggcaggg aggggacatc tgagggcttc 11400

 acagggctgc aaagggtaca gggattgcac cagggcagaa caggggaggg 11450

 tgttcaagga agagtggctc ttagcagagg cactttggaa ggtgtgaggc 11500

 ataaatgctt ccttctacgt aggccaacct caaaactttc agtaggaatg 11550

 ttgctatgat caagttgttc taacacttta gacttagtag taattatgaa 11600

 cctcacatag aaaaatttca tccagccata tgcctgtgga gtggaatatt 11650

 ctgtttagta gaaaaatcct ttagagttca gctctaacca gaaatcttgc 11700

 tgaagtatgt cagcaccttt tctcaccctg gtaagtacag tatttcaaga 11750

 gcacgctaag ggtggttttc attttacagg gctgttgatg atgggttaaa 11800

 aatgttcatt taagggctac ccccgtgttt aatagatgaa caccacttct 11850

 acacaaccct ccttggtact gggggaggga gagatctgac aaatactgcc 11900

 cattccccta ggctgactgg atttgagaac aaatacccac ccatttccac 11950

 catggtatgg taacttctct gagcttcagt ttccaagtga atttccatgt 12000

 aataggacat tcccattaaa tacaagctgt ttttactttt tcgcctccca 12050

 gggcctgtgc gatctggtcc cccagcctct cttgggcttt cttacactaa 12100

 ctctgtacct accatctcct gcctccctta ggcaggcacc tccaaccacc 12150

 acacactccc tgctgttttc cctgcctgga actttcccac cagccccacc 12200

 aagatcattt catccagtcc tgagctcagc ttaagggagg cttcttgcct 12250

 gtgggttccc tcacccccat gcctgtcctc caggctgggg caggttctta 12300

 gtttgcctgg aattgttctg tacctctttg tagcacgtag tgttgtgaaa 12350

 ctaagccact aattgagttt ctggctcccc tcctggggtt gtaagttttg 12400

 ttcattcatg agggccgact gtatttcctg gttactgtat cccagtgacc 12450

 agccacagga gatgtccaat aaagtatgtg atgaaatggt cttaaaaaaa 12500

 aaaaaaaaaa aaaaa 12515

<210> 2499
<211> 3256
<212> PRT
<213> Homo sapien

<400> 2499
 Met Trp Pro Thr Arg Arg Leu Val Thr Ile Lys Arg Ser Gly Val
   1               5                  10                  15

 Asp Gly Pro His Phe Pro Leu Ser Leu Ser Thr Cys Leu Phe Gly
                  20                  25                  30

 Arg Gly Ile Glu Cys Asp Ile Arg Ile Gln Leu Pro Val Val Ser
                  35                  40                  45

 Lys Gln His Cys Lys Ile Glu Ile His Glu Gln Glu Ala Ile Leu
                  50                  55                  60

 His Asn Phe Ser Ser Thr Asn Pro Thr Gln Val Asn Gly Ser Val
                  65                  70                  75

 Ile Asp Glu Pro Val Arg Leu Lys His Gly Asp Val Ile Thr Ile
                  80                  85                  90

 Ile Asp Arg Ser Phe Arg Tyr Glu Asn Glu Ser Leu Gln Asn Gly
                  95                 100                 105

 Arg Lys Ser Thr Glu Phe Pro Arg Lys Ile Arg Glu Gln Glu Pro
                 110                 115                 120

 Ala Arg Arg Val Ser Arg Ser Ser Phe Ser Ser Asp Pro Asp Glu
                 125                 130                 135

 Lys Ala Gln Asp Ser Lys Ala Tyr Ser Lys Ile Thr Glu Gly Lys
                 140                 145                 150

 Val Ser Gly Asn Pro Gln Val His Ile Lys Asn Val Lys Glu Asp
                 155                 160                 165

 Ser Thr Ala Asp Asp Ser Lys Asp Ser Val Ala Gln Gly Thr Thr
                 170                 175                 180

 Asn Val His Ser Ser Glu His Ala Gly Arg Asn Gly Arg Asn Ala
                 185                 190                 195

 Ala Asp Pro Ile Ser Gly Asp Phe Lys Glu Ile Ser Ser Val Lys
                 200                 205                 210

 Leu Val Ser Arg Tyr Gly Glu Leu Lys Ser Val Pro Thr Thr Gln
                 215                 220                 225

 Cys Leu Asp Asn Ser Lys Lys Asn Glu Ser Pro Phe Trp Lys Leu
                 230                 235                 240

 Tyr Glu Ser Val Lys Lys Glu Leu Asp Val Lys Ser Gln Lys Glu
                 245                 250                 255

 Asn Val Leu Gln Tyr Cys Arg Lys Ser Gly Leu Gln Thr Asp Tyr
                 260                 265                 270

 Ala Thr Glu Lys Glu Ser Ala Asp Gly Leu Gln Gly Glu Thr Gln
                 275                 280                 285

 Leu Leu Val Ser Arg Lys Ser Arg Pro Lys Ser Gly Gly Ser Gly
                 290                 295                 300

 His Ala Val Ala Glu Pro Ala Ser Pro Glu Gln Glu Leu Asp Gln
                 305                 310                 315

 Asn Lys Gly Lys Gly Arg Asp Val Glu Ser Val Gln Thr Pro Ser
                 320                 325                 330

 Lys Ala Val Gly Ala Ser Phe Pro Leu Tyr Glu Pro Ala Lys Met
                 335                 340                 345

 Lys Thr Pro Val Gln Tyr Ser Gln Gln Gln Asn Ser Pro Gln Lys
                 350                 355                 360

 His Lys Asn Lys Asp Leu Tyr Thr Thr Gly Arg Arg Glu Ser Val
                 365                 370                 375

 Asn Leu Gly Lys Ser Glu Gly Phe Lys Ala Gly Asp Lys Thr Leu
                 380                 385                 390

 Thr Pro Arg Lys Leu Ser Thr Arg Asn Arg Thr Pro Ala Lys Val
                 395                 400                 405

 Glu Asp Ala Ala Asp Ser Ala Thr Lys Pro Glu Asn Leu Ser Ser
                 410                 415                 420

 Lys Thr Arg Gly Ser Ile Pro Thr Asp Val Glu Val Leu Pro Thr
                 425                 430                 435

 Glu Thr Glu Ile His Asn Glu Pro Phe Leu Thr Leu Trp Leu Thr
                 440                 445                 450

 Gln Val Glu Arg Lys Ile Gln Lys Asp Ser Leu Ser Lys Pro Glu
                 455                 460                 465

 Lys Leu Gly Thr Thr Ala Gly Gln Met Cys Ser Gly Leu Pro Gly
                 470                 475                 480

 Leu Ser Ser Val Asp Ile Asn Asn Phe Gly Asp Ser Ile Asn Glu
                 485                 490                 495

 Ser Glu Gly Ile Pro Leu Lys Arg Arg Arg Val Ser Phe Gly Gly
                 500                 505                 510

 His Leu Arg Pro Glu Leu Phe Asp Glu Asn Leu Pro Pro Asn Thr
                 515                 520                 525

 Pro Leu Lys Arg Gly Glu Ala Pro Thr Lys Arg Lys Ser Leu Val
                 530                 535                 540

 Met His Thr Pro Pro Val Leu Lys Lys Ile Ile Lys Glu Gln Pro
                 545                 550                 555

 Gln Pro Ser Gly Lys Gln Glu Ser Gly Ser Glu Ile His Val Glu
                 560                 565                 570

 Val Lys Ala Gln Ser Leu Val Ile Ser Pro Pro Ala Pro Ser Pro
                 575                 580                 585

 Arg Lys Thr Pro Val Ala Ser Asp Gln Arg Arg Arg Ser Cys Lys
                 590                 595                 600

 Thr Ala Pro Ala Ser Ser Ser Lys Ser Gln Thr Glu Val Pro Lys
                 605                 610                 615

 Arg Gly Gly Glu Arg Val Ala Thr Cys Leu Gln Lys Arg Val Ser
                 620                 625                 630

 Ile Ser Arg Ser Gln His Asp Ile Leu Gln Met Ile Cys Ser Lys
                 635                 640                 645

 Arg Arg Ser Gly Ala Ser Glu Ala Asn Leu Ile Val Ala Lys Ser
                 650                 655                 660

 Trp Ala Asp Val Val Lys Leu Gly Ala Lys Gln Thr Gln Thr Lys
                 665                 670                 675

 Val Ile Lys His Gly Pro Gln Arg Ser Met Asn Lys Arg Gln Arg
                 680                 685                 690

 Arg Pro Ala Thr Pro Lys Lys Pro Val Gly Glu Val His Ser Gln
                 695                 700                 705

 Phe Ser Thr Gly His Ala Asn Ser Pro Cys Thr Ile Ile Ile Gly
                 710                 715                 720

 Lys Ala His Thr Glu Lys Val His Val Pro Ala Arg Pro Tyr Arg
                 725                 730                 735

 Val Leu Asn Asn Phe Ile Ser Asn Gln Lys Met Asp Phe Lys Glu
                 740                 745                 750

 Asp Leu Ser Gly Ile Ala Glu Met Phe Lys Thr Pro Val Lys Glu
                 755                 760                 765

 Gln Pro Gln Leu Thr Ser Thr Cys His Ile Ala Ile Ser Asn Ser
                 770                 775                 780

 Glu Asn Leu Leu Gly Lys Gln Phe Gln Gly Thr Asp Ser Gly Glu
                 785                 790                 795

 Glu Pro Leu Leu Pro Thr Ser Glu Ser Phe Gly Gly Asn Val Phe
                 800                 805                 810

 Phe Ser Ala Gln Asn Ala Ala Lys Gln Pro Ser Asp Lys Cys Ser
                 815                 820                 825

 Ala Ser Pro Pro Leu Arg Arg Gln Cys Ile Arg Glu Asn Gly Asn
                 830                 835                 840

 Val Ala Lys Thr Pro Arg Asn Thr Tyr Lys Met Thr Ser Leu Glu
                 845                 850                 855

 Thr Lys Thr Ser Asp Thr Glu Thr Glu Pro Ser Lys Thr Val Ser
                 860                 865                 870

 Thr Val Asn Arg Ser Gly Arg Ser Thr Glu Phe Arg Asn Ile Gln
                 875                 880                 885

 Lys Leu Pro Val Glu Ser Lys Ser Glu Glu Thr Asn Thr Glu Ile
                 890                 895                 900

 Val Glu Cys Ile Leu Lys Arg Gly Gln Lys Ala Thr Leu Leu Gln
                 905                 910                 915

 Gln Arg Arg Glu Gly Glu Met Lys Glu Ile Glu Arg Pro Phe Glu
                 920                 925                 930

 Thr Tyr Lys Glu Asn Ile Glu Leu Lys Glu Asn Asp Glu Lys Met
                 935                 940                 945

 Lys Ala Met Lys Arg Ser Arg Thr Trp Gly Gln Lys Cys Ala Pro
                 950                 955                 960

 Met Ser Asp Leu Thr Asp Leu Lys Ser Leu Pro Asp Thr Glu Leu
                 965                 970                 975

 Met Lys Asp Thr Ala Arg Gly Gln Asn Leu Leu Gln Thr Gln Asp
                 980                 985                 990

 His Ala Lys Ala Pro Lys Ser Glu Lys Gly Lys Ile Thr Lys Met
                 995                1000                1005

 Pro Cys Gln Ser Leu Gln Pro Glu Pro Ile Asn Thr Pro Thr His
                1010                1015                1020

 Thr Lys Gln Gln Leu Lys Ala Ser Leu Gly Lys Val Gly Val Lys
                1025                1030                1035

 Glu Glu Leu Leu Ala Val Gly Lys Phe Thr Arg Thr Ser Gly Glu
                1040                1045                1050

 Thr Thr His Thr His Arg Glu Pro Ala Gly Asp Gly Lys Ser Ile
                1055                1060                1065

 Arg Thr Phe Lys Glu Ser Pro Lys Gln Ile Leu Asp Pro Ala Ala
                1070                1075                1080

 Arg Val Thr Gly Met Lys Lys Trp Pro Arg Thr Pro Lys Glu Glu
                1085                1090                1095

 Ala Gln Ser Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln
                1100                1105                1110

 Thr Pro Gly Pro Ser Glu Glu Ser Met Thr Asp Glu Lys Thr Thr
                1115                1120                1125

 Lys Ile Ala Cys Lys Ser Pro Pro Pro Glu Ser Val Asp Thr Pro
                1130                1135                1140

 Thr Ser Thr Lys Gln Trp Pro Lys Arg Ser Leu Arg Lys Ala Asp
                1145                1150                1155

 Val Glu Glu Glu Phe Leu Ala Leu Arg Lys Leu Thr Pro Ser Ala
                1160                1165                1170

 Gly Lys Ala Met Leu Thr Pro Lys Pro Ala Gly Gly Asp Glu Lys
                1175                1180                1185

 Asp Ile Lys Ala Phe Met Gly Thr Pro Val Gln Lys Leu Asp Leu
                1190                1195                1200

 Ala Gly Thr Leu Pro Gly Ser Lys Arg Gln Leu Gln Thr Pro Lys
                1205                1210                1215

 Glu Lys Ala Gln Ala Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu
                1220                1225                1230

 Phe Gln Thr Pro Gly His Thr Glu Glu Leu Val Ala Ala Gly Lys
                1235                1240                1245

 Thr Thr Lys Ile Pro Cys Asp Ser Pro Gln Ser Asp Pro Val Asp
                1250                1255                1260

 Thr Pro Thr Ser Thr Lys Gln Arg Pro Lys Arg Ser Ile Arg Lys
                1265                1270                1275

 Ala Asp Val Glu Gly Glu Leu Leu Ala Cys Arg Asn Leu Met Pro
                1280                1285                1290

 Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ser Val Gly Glu
                1295                1300                1305

 Glu Lys Asp Ile Ile Ile Phe Val Gly Thr Pro Val Gln Lys Leu
                1310                1315                1320

 Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Pro Gln Thr
                1325                1330                1335

 Pro Lys Glu Glu Ala Gln Ala Leu Glu Asp Leu Thr Gly Phe Lys
                1340                1345                1350

 Glu Leu Phe Gln Thr Pro Gly His Thr Glu Glu Ala Val Ala Ala
                1355                1360                1365

 Gly Lys Thr Thr Lys Met Pro Cys Glu Ser Ser Pro Pro Glu Ser
                1370                1375                1380

 Ala Asp Thr Pro Thr Ser Thr Arg Arg Gln Pro Lys Thr Pro Leu
                1385                1390                1395

 Glu Lys Arg Asp Val Gln Lys Glu Leu Ser Ala Leu Lys Lys Leu
                1400                1405                1410

 Thr Gln Thr Ser Gly Glu Thr Thr His Thr Asp Lys Val Pro Gly
                1415                1420                1425

 Gly Glu Asp Lys Ser Ile Asn Ala Phe Arg Glu Thr Ala Lys Gln
                1430                1435                1440

 Lys Leu Asp Pro Ala Ala Ser Val Thr Gly Ser Lys Arg His Pro
                1445                1450                1455

 Lys Thr Lys Glu Lys Ala Gln Pro Leu Glu Asp Leu Ala Gly Trp
                1460                1465                1470

 Lys Glu Leu Phe Gln Thr Pro Val Cys Thr Asp Lys Pro Thr Thr
                1475                1480                1485

 His Glu Lys Thr Thr Lys Ile Ala Cys Arg Ser Gln Pro Asp Pro
                1490                1495                1500

 Val Asp Thr Pro Thr Ser Ser Lys Pro Gln Ser Lys Arg Ser Leu
                1505                1510                1515

 Arg Lys Val Asp Val Glu Glu Glu Phe Phe Ala Leu Arg Lys Arg
                1520                1525                1530

 Thr Pro Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ala Val
                1535                1540                1545

 Ser Gly Glu Lys Asn Ile Tyr Ala Phe Met Gly Thr Pro Val Gln
                1550                1555                1560

 Lys Leu Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Leu
                1565                1570                1575

 Gln Thr Pro Lys Glu Lys Ala Gln Ala Leu Glu Asp Leu Ala Gly
                1580                1585                1590

 Phe Lys Glu Leu Phe Gln Thr Arg Gly His Thr Glu Glu Ser Met
                1595                1600                1605

 Thr Asn Asp Lys Thr Ala Lys Val Ala Cys Lys Ser Ser Gln Pro
                1610                1615                1620

 Asp Leu Asp Lys Asn Pro Ala Ser Ser Lys Arg Arg Leu Lys Thr
                1625                1630                1635

 Ser Leu Gly Lys Val Gly Val Lys Glu Glu Leu Leu Ala Val Gly
                1640                1645                1650

 Lys Leu Thr Gln Thr Ser Gly Glu Thr Thr His Thr His Thr Glu
                1655                1660                1665

 Pro Thr Gly Asp Gly Lys Ser Met Lys Ala Phe Met Glu Ser Pro
                1670                1675                1680

 Lys Gln Ile Leu Asp Ser Ala Ala Ser Leu Thr Gly Ser Lys Arg
                1685                1690                1695

 Gln Leu Arg Thr Pro Lys Gly Lys Ser Glu Val Pro Glu Asp Leu
                1700                1705                1710

 Ala Gly Phe Ile Glu Leu Phe Gln Thr Pro Ser His Thr Lys Glu
                1715                1720                1725

 Ser Met Thr Asn Glu Lys Thr Thr Lys Val Ser Tyr Arg Ala Ser
                1730                1735                1740

 Gln Pro Asp Leu Val Asp Thr Pro Thr Ser Ser Lys Pro Gln Pro
                1745                1750                1755

 Lys Arg Ser Leu Arg Lys Ala Asp Thr Glu Glu Glu Phe Leu Ala
                1760                1765                1770

 Phe Arg Lys Gln Thr Pro Ser Ala Gly Lys Ala Met His Thr Pro
                1775                1780                1785

 Lys Pro Ala Val Gly Glu Glu Lys Asp Ile Asn Thr Phe Leu Gly
                1790                1795                1800

 Thr Pro Val Gln Lys Leu Asp Gln Pro Gly Asn Leu Pro Gly Ser
                1805                1810                1815

 Asn Arg Arg Leu Gln Thr Arg Lys Glu Lys Ala Gln Ala Leu Glu
                1820                1825                1830

 Glu Leu Thr Gly Phe Arg Glu Leu Phe Gln Thr Pro Cys Thr Asp
                1835                1840                1845

 Asn Pro Thr Ala Asp Glu Lys Thr Thr Lys Lys Ile Leu Cys Lys
                1850                1855                1860

 Ser Pro Gln Ser Asp Pro Ala Asp Thr Pro Thr Asn Thr Lys Gln
                1865                1870                1875

 Arg Pro Lys Arg Ser Leu Lys Lys Ala Asp Val Glu Glu Glu Phe
                1880                1885                1890

 Leu Ala Phe Arg Lys Leu Thr Pro Ser Ala Gly Lys Ala Met His
                1895                1900                1905

 Thr Pro Lys Ala Ala Val Gly Glu Glu Lys Asp Ile Asn Thr Phe
                1910                1915                1920

 Val Gly Thr Pro Val Glu Lys Leu Asp Leu Leu Gly Asn Leu Pro
                1925                1930                1935

 Gly Ser Lys Arg Arg Pro Gln Thr Pro Lys Glu Lys Ala Lys Ala
                1940                1945                1950

 Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr Pro Gly
                1955                1960                1965

 His Thr Glu Glu Ser Met Thr Asp Asp Lys Ile Thr Glu Val Ser
                1970                1975                1980

 Cys Lys Ser Pro Gln Pro Asp Pro Val Lys Thr Pro Thr Ser Ser
                1985                1990                1995

 Lys Gln Arg Leu Lys Ile Ser Leu Gly Lys Val Gly Val Lys Glu
                2000                2005                2010

 Glu Val Leu Pro Val Gly Lys Leu Thr Gln Thr Ser Gly Lys Thr
                2015                2020                2025

 Thr Gln Thr His Arg Glu Thr Ala Gly Asp Gly Lys Ser Ile Lys
                2030                2035                2040

 Ala Phe Lys Glu Ser Ala Lys Gln Met Leu Asp Pro Ala Asn Tyr
                2045                2050                2055

 Gly Thr Gly Met Glu Arg Trp Pro Arg Thr Pro Lys Glu Glu Ala
                2060                2065                2070

 Gln Ser Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr
                2075                2080                2085

 Pro Asp His Thr Glu Glu Ser Thr Thr Asp Asp Lys Thr Thr Lys
                2090                2095                2100

 Ile Ala Cys Lys Ser Pro Pro Pro Glu Ser Met Asp Thr Pro Thr
                2105                2110                2115

 Ser Thr Arg Arg Arg Pro Lys Thr Pro Leu Gly Lys Arg Asp Ile
                2120                2125                2130

 Val Glu Glu Leu Ser Ala Leu Lys Gln Leu Thr Gln Thr Thr His
                2135                2140                2145

 Thr Asp Lys Val Pro Gly Asp Glu Asp Lys Gly Ile Asn Val Phe
                2150                2155                2160

 Arg Glu Thr Ala Lys Gln Lys Leu Asp Pro Ala Ala Ser Val Thr
                2165                2170                2175

 Gly Ser Lys Arg Gln Pro Arg Thr Pro Lys Gly Lys Ala Gln Pro
                2180                2185                2190

 Leu Glu Asp Leu Ala Gly Leu Lys Glu Leu Phe Gln Thr Pro Val
                2195                2200                2205

 Cys Thr Asp Lys Pro Thr Thr His Glu Lys Thr Thr Lys Ile Ala
                2210                2215                2220

 Cys Arg Ser Pro Gln Pro Asp Pro Val Gly Thr Pro Thr Ile Phe
                2225                2230                2235

 Lys Pro Gln Ser Lys Arg Ser Leu Arg Lys Ala Asp Val Glu Glu
                2240                2245                2250

 Glu Ser Leu Ala Leu Arg Lys Arg Thr Pro Ser Val Gly Lys Ala
                2255                2260                2265

 Met Asp Thr Pro Lys Pro Ala Gly Gly Asp Glu Lys Asp Met Lys
                2270                2275                2280

 Ala Phe Met Gly Thr Pro Val Gln Lys Leu Asp Leu Pro Gly Asn
                2285                2290                2295

 Leu Pro Gly Ser Lys Arg Trp Pro Gln Thr Pro Lys Glu Lys Ala
                2300                2305                2310

 Gln Ala Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr
                2315                2320                2325

 Pro Gly Thr Asp Lys Pro Thr Thr Asp Glu Lys Thr Thr Lys Ile
                2330                2335                2340

 Ala Cys Lys Ser Pro Gln Pro Asp Pro Val Asp Thr Pro Ala Ser
                2345                2350                2355

 Thr Lys Gln Arg Pro Lys Arg Asn Leu Arg Lys Ala Asp Val Glu
                2360                2365                2370

 Glu Glu Phe Leu Ala Leu Arg Lys Arg Thr Pro Ser Ala Gly Lys
                2375                2380                2385

 Ala Met Asp Thr Pro Lys Pro Ala Val Ser Asp Glu Lys Asn Ile
                2390                2395                2400

 Asn Thr Phe Val Glu Thr Pro Val Gln Lys Leu Asp Leu Leu Gly
                2405                2410                2415

 Asn Leu Pro Gly Ser Lys Arg Gln Pro Gln Thr Pro Lys Glu Lys
                2420                2425                2430

 Ala Glu Ala Leu Glu Asp Leu Val Gly Phe Lys Glu Leu Phe Gln
                2435                2440                2445

 Thr Pro Gly His Thr Glu Glu Ser Met Thr Asp Asp Lys Ile Thr
                2450                2455                2460

 Glu Val Ser Cys Lys Ser Pro Gln Pro Glu Ser Phe Lys Thr Ser
                2465                2470                2475

 Arg Ser Ser Lys Gln Arg Leu Lys Ile Pro Leu Val Lys Val Asp
                2480                2485                2490

 Met Lys Glu Glu Pro Leu Ala Val Ser Lys Leu Thr Arg Thr Ser
                2495                2500                2505

 Gly Glu Thr Thr Gln Thr His Thr Glu Pro Thr Gly Asp Ser Lys
                2510                2515                2520

 Ser Ile Lys Ala Phe Lys Glu Ser Pro Lys Gln Ile Leu Asp Pro
                2525                2530                2535

 Ala Ala Ser Val Thr Gly Ser Arg Arg Gln Leu Arg Thr Arg Lys
                2540                2545                2550

 Glu Lys Ala Arg Ala Leu Glu Asp Leu Val Asp Phe Lys Glu Leu
                2555                2560                2565

 Phe Ser Ala Pro Gly His Thr Glu Glu Ser Met Thr Ile Asp Lys
                2570                2575                2580

 Asn Thr Lys Ile Pro Cys Lys Ser Pro Pro Pro Glu Leu Thr Asp
                2585                2590                2595

 Thr Ala Thr Ser Thr Lys Arg Cys Pro Lys Thr Arg Pro Arg Lys
                2600                2605                2610

 Glu Val Lys Glu Glu Leu Ser Ala Val Glu Arg Leu Thr Gln Thr
                2615                2620                2625

 Ser Gly Gln Ser Thr His Thr His Lys Glu Pro Ala Ser Gly Asp
                2630                2635                2640

 Glu Gly Ile Lys Val Leu Lys Gln Arg Ala Lys Lys Lys Pro Asn
                2645                2650                2655

 Pro Val Glu Glu Glu Pro Ser Arg Arg Arg Pro Arg Ala Pro Lys
                2660                2665                2670

 Glu Lys Ala Gln Pro Leu Glu Asp Leu Ala Gly Phe Thr Glu Leu
                2675                2680                2685

 Ser Glu Thr Ser Gly His Thr Gln Glu Ser Leu Thr Ala Gly Lys
                2690                2695                2700

 Ala Thr Lys Ile Pro Cys Glu Ser Pro Pro Leu Glu Val Val Asp
                2705                2710                2715

 Thr Thr Ala Ser Thr Lys Arg His Leu Arg Thr Arg Val Gln Lys
                2720                2725                2730

 Val Gln Val Lys Glu Glu Pro Ser Ala Val Lys Phe Thr Gln Thr
                2735                2740                2745

 Ser Gly Glu Thr Thr Asp Ala Asp Lys Glu Pro Ala Gly Glu Asp
                2750                2755                2760

 Lys Gly Ile Lys Ala Leu Lys Glu Ser Ala Lys Gln Thr Pro Ala
                2765                2770                2775

 Pro Ala Ala Ser Val Thr Gly Ser Arg Arg Arg Pro Arg Ala Pro
                2780                2785                2790

 Arg Glu Ser Ala Gln Ala Ile Glu Asp Leu Ala Gly Phe Lys Asp
                2795                2800                2805

 Pro Ala Ala Gly His Thr Glu Glu Ser Met Thr Asp Asp Lys Thr
                2810                2815                2820

 Thr Lys Ile Pro Cys Lys Ser Ser Pro Glu Leu Glu Asp Thr Ala
                2825                2830                2835

 Thr Ser Ser Lys Arg Arg Pro Arg Thr Arg Ala Gln Lys Val Glu
                2840                2845                2850

 Val Lys Glu Glu Leu Leu Ala Val Gly Lys Leu Thr Gln Thr Ser
                2855                2860                2865

 Gly Glu Thr Thr His Thr Asp Lys Glu Pro Val Gly Glu Gly Lys
                2870                2875                2880

 Gly Thr Lys Ala Phe Lys Gln Pro Ala Lys Arg Asn Val Asp Ala
                2885                2890                2895

 Glu Asp Val Ile Gly Ser Arg Arg Gln Pro Arg Ala Pro Lys Glu
                2900                2905                2910

 Lys Ala Gln Pro Leu Glu Asp Leu Ala Ser Phe Gln Glu Leu Ser
                2915                2920                2925

 Gln Thr Pro Gly His Thr Glu Glu Leu Ala Asn Gly Ala Ala Asp
                2930                2935                2940

 Ser Phe Thr Ser Ala Pro Lys Gln Thr Pro Asp Ser Gly Lys Pro
                2945                2950                2955

 Leu Lys Ile Ser Arg Arg Val Leu Arg Ala Pro Lys Val Glu Pro
                2960                2965                2970

 Val Gly Asp Val Val Ser Thr Arg Asp Pro Val Lys Ser Gln Ser
                2975                2980                2985

 Lys Ser Asn Thr Ser Leu Pro Pro Leu Pro Phe Lys Arg Gly Gly
                2990                2995                3000

 Gly Lys Asp Gly Ser Val Thr Gly Thr Lys Arg Leu Arg Cys Met
                3005                3010                3015

 Pro Ala Pro Glu Glu Ile Val Glu Glu Leu Pro Ala Ser Lys Lys
                3020                3025                3030

 Gln Arg Val Ala Pro Arg Ala Arg Gly Lys Ser Ser Glu Pro Val
                3035                3040                3045

 Val Ile Met Lys Arg Ser Leu Arg Thr Ser Ala Lys Arg Ile Glu
                3050                3055                3060

 Pro Ala Glu Glu Leu Asn Ser Asn Asp Met Lys Thr Asn Lys Glu
                3065                3070                3075

 Glu His Lys Leu Gln Asp Ser Val Pro Glu Asn Lys Gly Ile Ser
                3080                3085                3090

 Leu Arg Ser Arg Arg Gln Asp Lys Thr Glu Ala Glu Gln Gln Ile
                3095                3100                3105

 Thr Glu Val Phe Val Leu Ala Glu Arg Ile Glu Ile Asn Arg Asn
                3110                3115                3120

 Glu Lys Lys Pro Met Lys Thr Ser Pro Glu Met Asp Ile Gln Asn
                3125                3130                3135

 Pro Asp Asp Gly Ala Arg Lys Pro Ile Pro Arg Asp Lys Val Thr
                3140                3145                3150

 Glu Asn Lys Arg Cys Leu Arg Ser Ala Arg Gln Asn Glu Ser Ser
                3155                3160                3165

 Gln Pro Lys Val Ala Glu Glu Ser Gly Gly Gln Lys Ser Ala Lys
                3170                3175                3180

 Val Leu Met Gln Asn Gln Lys Gly Lys Gly Glu Ala Gly Asn Ser
                3185                3190                3195

 Asp Ser Met Cys Leu Arg Ser Arg Lys Thr Lys Ser Gln Pro Ala
                3200                3205                3210

 Ala Ser Thr Leu Glu Ser Lys Ser Val Gln Arg Val Thr Arg Ser
                3215                3220                3225

 Val Lys Arg Cys Ala Glu Asn Pro Lys Lys Ala Glu Asp Asn Val
                3230                3235                3240

 Cys Val Lys Lys Ile Thr Thr Arg Ser His Arg Asp Ser Glu Asp
                3245                3250                3255

 Ile


<210> 2500
<211> 11435
<212> DNA
<213> Homo sapien

<400> 2500
 ctaccgggcg gaggtgagcg cggcgccggc tcctcctgcg gcggactttg 50

 ggtgcgactt gacgagcggt ggttcgacaa gtggccttgc gggccggatc 100

 gtcccagtgg aagagttgta aatttgcttc tggccttccc ctacggatta 150

 tacctggcct tcccctacgg attatactca acttactgtt tagaaaatgt 200

 ggcccacgag acgcctggtt actatcaaaa ggagcggggt cgacggtccc 250

 cactttcccc tgagcctcag cacctgcttg tttggaaggg gtattgaatg 300

 tgacatccgt atccagcttc ctgttgtgtc aaaacaacat tgcaaaattg 350

 aaatccatga gcaggaggca atattacata atttcagttc cacaaatcca 400

 acacaagtaa atgggtctgt tattgatgag cctgtacggc taaaacatgg 450

 agatgtaata actattattg atcgttcctt caggtatgaa aatgaaagtc 500

 ttcagaatgg aaggaagtca actgaatttc caagaaaaat acgtgaacag 550

 gagccagcac gtcgtgtctc aagatctagc ttctcttctg accctgatga 600

 gagtgaggga atacctttga aaagaaggcg tgtgtccttt ggtgggcacc 650

 taagacctga actatttgat gaaaacttgc ctcctaatac gcctctcaaa 700

 aggggagaag ccccaaccaa aagaaagtct ctggtaatgc acactccacc 750

 tgtcctgaag aaaatcatca aggaacagcc tcaaccatca ggaaaacaag 800

 agtcaggttc agaaatccat gtggaagtga aggcacaaag cttggttata 850

 agccctccag ctcctagtcc taggaaaact ccagttgcca gtgatcaacg 900

 ccgtaggtcc tgcaaaacag cccctgcttc cagcagcaaa tctcagacag 950

 aggttcctaa gagaggagga gaaagagtgg caacctgcct tcaaaagaga 1000

 gtgtctatca gccgaagtca acatgatatt ttacagatga tatgttccaa 1050

 aagaagaagt ggtgcttcgg aagcaaatct gattgttgca aaatcatggg 1100

 cagatgtagt aaaacttggt gcaaaacaaa cacaaactaa agtcataaaa 1150

 catggtcctc aaaggtcaat gaacaaaagg caaagaagac ctgctactcc 1200

 aaagaagcct gtgggcgaag ttcacagtca atttagtaca ggccacgcaa 1250

 actctccttg taccataata atagggaaag ctcatactga aaaagtacat 1300

 gtgcctgctc gaccctacag agtgctcaac aacttcattt ccaaccaaaa 1350

 aatggacttt aaggaagatc tttcaggaat agctgaaatg ttcaagaccc 1400

 cagtgaagga gcaaccgcag ttgacaagca catgtcacat cgctatttca 1450

 aattcagaga atttgcttgg aaaacagttt caaggaactg attcaggaga 1500

 agaacctctg ctccccacct cagagagttt tggaggaaat gtgttcttca 1550

 gtgcacagaa tgcagcaaaa cagccatctg ataaatgctc tgcaagccct 1600

 cccttaagac ggcagtgtat tagagaaaat ggaaacgtag caaaaacgcc 1650

 caggaacacc tacaaaatga cttctctgga gacaaaaact tcagatactg 1700

 agacagagcc ttcaaaaaca gtatccactg taaacaggtc aggaaggtct 1750

 acagagttca ggaatataca gaagctacct gtggaaagta agagtgaaga 1800

 aacaaataca gaaattgttg agtgcatcct aaaaagaggt cagaaggcaa 1850

 cactactaca acaaaggaga gaaggagaga tgaaggaaat agaaagacct 1900

 tttgagacat ataaggaaaa tattgaatta aaagaaaacg atgaaaagat 1950

 gaaagcaatg aagagatcaa gaacttgggg gcagaaatgt gcaccaatgt 2000

 ctgacctgac agacctcaag agcttgcctg atacagaact catgaaagac 2050

 acggcacgtg gccagaatct cctccaaacc caagatcatg ccaaggcacc 2100

 aaagagtgag aaaggcaaaa tcactaaaat gccctgccag tcattacaac 2150

 cagaaccaat aaacacccca acacacacaa aacaacagtt gaaggcatcc 2200

 ctggggaaag taggtgtgaa agaagagctc ctagcagtcg gcaagttcac 2250

 acggacgtca ggggagacca cgcacacgca cagagagcca gcaggagatg 2300

 gcaagagcat cagaacgttt aaggagtctc caaagcagat cctggaccca 2350

 gcagcccgtg taactggaat gaagaagtgg ccaagaacgc ctaaggaaga 2400

 ggcccagtca ctagaagacc tggctggctt caaagagctc ttccagacac 2450

 caggtccctc tgaggaatca atgactgatg agaaaactac caaaatagcc 2500

 tgcaaatctc caccaccaga atcagtggac actccaacaa gcacaaagca 2550

 atggcctaag agaagtctca ggaaagcaga tgtagaggaa gaattcttag 2600

 cactcaggaa actaacacca tcagcaggga aagccatgct tacgcccaaa 2650

 ccagcaggag gtgatgagaa agacattaaa gcatttatgg gaactccagt 2700

 gcagaaactg gacctggcag gaactttacc tggcagcaaa agacagctac 2750

 agactcctaa ggaaaaggcc caggctctag aagacctggc tggctttaaa 2800

 gagctcttcc agactcctgg tcacaccgag gaattagtgg ctgctggtaa 2850

 aaccactaaa ataccctgcg actctccaca gtcagaccca gtggacaccc 2900

 caacaagcac aaagcaacga cccaagagaa gtatcaggaa agcagatgta 2950

 gagggagaac tcttagcgtg caggaatcta atgccatcag caggcaaagc 3000

 catgcacacg cctaaaccat cagtaggtga agagaaagac atcatcatat 3050

 ttgtgggaac tccagtgcag aaactggacc tgacagagaa cttaaccggc 3100

 agcaagagac ggccacaaac tcctaaggaa gaggcccagg ctctggaaga 3150

 cctgactggc tttaaagagc tcttccagac ccctggtcat actgaagaag 3200

 cagtggctgc tggcaaaact actaaaatgc cctgcgaatc ttctccacca 3250

 gaatcagcag acaccccaac aagcacaaga aggcagccca agacaccttt 3300

 ggagaaaagg gacgtacaga aggagctctc agccctgaag aagctcacac 3350

 agacatcagg ggaaaccaca cacacagata aagtaccagg aggtgaggat 3400

 aaaagcatca acgcgtttag ggaaactgca aaacagaaac tggacccagc 3450

 agcaagtgta actggtagca agaggcaccc aaaaactaag gaaaaggccc 3500

 aacccctaga agacctggct ggctggaaag agctcttcca gacaccagta 3550

 tgcactgaca agcccacgac tcacgagaaa actaccaaaa tagcctgcag 3600

 atcacaacca gacccagtgg acacaccaac aagctccaag ccacagtcca 3650

 agagaagtct caggaaagtg gacgtagaag aagaattctt cgcactcagg 3700

 aaacgaacac catcagcagg caaagccatg cacacaccca aaccagcagt 3750

 aagtggtgag aaaaacatct acgcatttat gggaactcca gtgcagaaac 3800

 tggacctgac agagaactta actggcagca agagacggct acaaactcct 3850

 aaggaaaagg cccaggctct agaagacctg gctggcttta aagagctctt 3900

 ccagacacga ggtcacactg aggaatcaat gactaacgat aaaactgcca 3950

 aagtagcctg caaatcttca caaccagacc tagacaaaaa cccagcaagc 4000

 tccaagcgac ggctcaagac atccctgggg aaagtgggcg tgaaagaaga 4050

 gctcctagca gttggcaagc tcacacagac atcaggagag actacacaca 4100

 cacacacaga gccaacagga gatggtaaga gcatgaaagc atttatggag 4150

 tctccaaagc agatcttaga ctcagcagca agtctaactg gcagcaagag 4200

 gcagctgaga actcctaagg gaaagtctga agtccctgaa gacctggccg 4250

 gcttcatcga gctcttccag acaccaagtc acactaagga atcaatgact 4300

 aatgaaaaaa ctaccaaagt atcctacaga gcttcacagc cagacctagt 4350

 ggacacccca acaagctcca agccacagcc caagagaagt ctcaggaaag 4400

 cagacactga agaagaattt ttagcattta ggaaacaaac gccatcagca 4450

 ggcaaagcca tgcacacacc caaaccagca gtaggtgaag agaaagacat 4500

 caacacgttt ttgggaactc cagtgcagaa actggaccag ccaggaaatt 4550

 tacctggcag caatagacgg ctacaaactc gtaaggaaaa ggcccaggct 4600

 ctagaagaac tgactggctt cagagagctt ttccagacac catgcactga 4650

 taaccccaca gctgatgaga aaactaccaa aaaaatactc tgcaaatctc 4700

 cgcaatcaga cccagcggac accccaacaa acacaaagca acggcccaag 4750

 agaagcctca agaaagcaga cgtagaggaa gaatttttag cattcaggaa 4800

 actaacacca tcagcaggca aagccatgca cacgcctaaa gcagcagtag 4850

 gtgaagagaa agacatcaac acatttgtgg ggactccagt ggagaaactg 4900

 gacctgctag gaaatttacc tggcagcaag agacggccac aaactcctaa 4950

 agaaaaggcc aaggctctag aagatctggc tggcttcaaa gagctcttcc 5000

 agacaccagg tcacactgag gaatcaatga ccgatgacaa aatcacagaa 5050

 gtatcctgca aatctccaca accagaccca gtcaaaaccc caacaagctc 5100

 caagcaacga ctcaagatat ccttggggaa agtaggtgtg aaagaagagg 5150

 tcctaccagt cggcaagctc acacagacgt cagggaagac cacacagaca 5200

 cacagagaga cagcaggaga tggaaagagc atcaaagcgt ttaaggaatc 5250

 tgcaaagcag atgctggacc cagcaaacta tggaactggg atggagaggt 5300

 ggccaagaac acctaaggaa gaggcccaat cactagaaga cctggccggc 5350

 ttcaaagagc tcttccagac accagaccac actgaggaat caacaactga 5400

 tgacaaaact accaaaatag cctgcaaatc tccaccacca gaatcaatgg 5450

 acactccaac aagcacaagg aggcggccca aaacaccttt ggggaaaagg 5500

 gatatagtgg aagagctctc agccctgaag cagctcacac agaccacaca 5550

 cacagacaaa gtaccaggag atgaggataa aggcatcaac gtgttcaggg 5600

 aaactgcaaa acagaaactg gacccagcag caagtgtaac tggtagcaag 5650

 aggcagccaa gaactcctaa gggaaaagcc caacccctag aagacttggc 5700

 tggcttgaaa gagctcttcc agacaccagt atgcactgac aagcccacga 5750

 ctcacgagaa aactaccaaa atagcctgca gatctccaca accagaccca 5800

 gtgggtaccc caacaatctt caagccacag tccaagagaa gtctcaggaa 5850

 agcagacgta gaggaagaat ccttagcact caggaaacga acaccatcag 5900

 tagggaaagc tatggacaca cccaaaccag caggaggtga tgagaaagac 5950

 atgaaagcat ttatgggaac tccagtgcag aaattggacc tgccaggaaa 6000

 tttacctggc agcaaaagat ggccacaaac tcctaaggaa aaggcccagg 6050

 ctctagaaga cctggctggc ttcaaagagc tcttccagac accaggcact 6100

 gacaagccca cgactgatga gaaaactacc aaaatagcct gcaaatctcc 6150

 acaaccagac ccagtggaca ccccagcaag cacaaagcaa cggcccaaga 6200

 gaaacctcag gaaagcagac gtagaggaag aatttttagc actcaggaaa 6250

 cgaacaccat cagcaggcaa agccatggac accccaaaac cagcagtaag 6300

 tgatgagaaa aatatcaaca catttgtgga aactccagtg cagaaactgg 6350

 acctgctagg aaatttacct ggcagcaaga gacagccaca gactcctaag 6400

 gaaaaggctg aggctctaga ggacctggtt ggcttcaaag aactcttcca 6450

 gacaccaggt cacactgagg aatcaatgac tgatgacaaa atcacagaag 6500

 tatcctgtaa atctccacag ccagagtcat tcaaaacctc aagaagctcc 6550

 aagcaaaggc tcaagatacc cctggtgaaa gtggacatga aagaagagcc 6600

 cctagcagtc agcaagctca cacggacatc aggggagact acgcaaacac 6650

 acacagagcc aacaggagat agtaagagca tcaaagcgtt taaggagtct 6700

 ccaaagcaga tcctggaccc agcagcaagt gtaactggta gcaggaggca 6750

 gctgagaact cgtaaggaaa aggcccgtgc tctagaagac ctggttgact 6800

 tcaaagagct cttctcagca ccaggtcaca ctgaagagtc aatgactatt 6850

 gacaaaaaca caaaaattcc ctgcaaatct cccccaccag aactaacaga 6900

 cactgccacg agcacaaaga gatgccccaa gacacgtccc aggaaagaag 6950

 taaaagagga gctctcagca gttgagaggc tcacgcaaac atcagggcaa 7000

 agcacacaca cacacaaaga accagcaagc ggtgatgagg gcatcaaagt 7050

 attgaagcaa cgtgcaaaga agaaaccaaa cccagtagaa gaggaaccca 7100

 gcaggagaag gccaagagca cctaaggaaa aggcccaacc cctggaagac 7150

 ctggccggct tcacagagct ctctgaaaca tcaggtcaca ctcaggaatc 7200

 actgactgct ggcaaagcca ctaaaatacc ctgcgaatct cccccactag 7250

 aagtggtaga caccacagca agcacaaaga ggcatctcag gacacgtgtg 7300

 cagaaggtac aagtaaaaga agagccttca gcagtcaagt tcacacaaac 7350

 atcaggggaa accacggatg cagacaaaga accagcaggt gaagataaag 7400

 gcatcaaagc attgaaggaa tctgcaaaac agacaccggc tccagcagca 7450

 agtgtaactg gcagcaggag acggccaaga gcacccaggg aaagtgccca 7500

 agccatagaa gacctagctg gcttcaaaga cccagcagca ggtcacactg 7550

 aagaatcaat gactgatgac aaaaccacta aaataccctg caaatcatca 7600

 ccagaactag aagacaccgc aacaagctca aagagacggc ccaggacacg 7650

 tgcccagaaa gtagaagtga aggaggagct gttagcagtt ggcaagctca 7700

 cacaaacctc aggggagacc acgcacaccg acaaagagcc ggtaggtgag 7750

 ggcaaaggca cgaaagcatt taagcaacct gcaaagcgga acgtggacgc 7800

 agaagatgta attggcagca ggagacagcc aagagcacct aaggaaaagg 7850

 cccaacccct ggaagacctg gccagcttcc aagagctctc tcaaacacca 7900

 ggccacactg aggaactggc aaatggtgct gctgatagct ttacaagcgc 7950

 tccaaagcaa acacctgaca gtggaaaacc tctaaaaata tccagaagag 8000

 ttcttcgggc ccctaaagta gaacccgtgg gagacgtggt aagcaccaga 8050

 gaccctgtaa aatcacaaag caaaagcaac acttccctgc ccccactgcc 8100

 cttcaagagg ggaggtggca aagatggaag cgtcacggga accaagaggc 8150

 tgcgctgcat gccagcacca gaggaaattg tggaggagct gccagccagc 8200

 aagaagcaga gggttgctcc cagggcaaga ggcaaatcat ccgaacccgt 8250

 ggtcatcatg aagagaagtt tgaggacttc tgcaaaaaga attgaacctg 8300

 cggaagagct gaacagcaac gacatgaaaa ccaacaaaga ggaacacaaa 8350

 ttacaagact cggtccctga aaataaggga atatccctgc gctccagacg 8400

 ccaagataag actgaggcag aacagcaaat aactgaggtc tttgtattag 8450

 cagaaagaat agaaataaac agaaatgaaa agaagcccat gaagacctcc 8500

 ccagagatgg acattcagaa tccagatgat ggagcccgga aacccatacc 8550

 tagagacaaa gtcactgaga acaaaaggtg cttgaggtct gctagacaga 8600

 atgagagctc ccagcctaag gtggcagagg agagcggagg gcagaagagt 8650

 gcgaaggttc tcatgcagaa tcagaaaggg aaaggagaag caggaaattc 8700

 agactccatg tgcctgagat caagaaagac aaaaagccag cctgcagcaa 8750

 gcactttgga gagcaaatct gtgcagagag taacgcggag tgtcaagagg 8800

 tgtgcagaaa atccaaagaa ggctgaggac aatgtgtgtg tcaagaaaat 8850

 aacaaccaga agtcataggg acagtgaaga tatttgacag aaaaatcgaa 8900

 ctgggaaaaa tataataaag ttagttttgt gataagttct agtgcagttt 8950

 ttgtcataaa ttacaagtga attctgtaag taaggctgtc agtctgctta 9000

 agggaagaaa actttggatt tgctgggtct gaatcggctt cataaactcc 9050

 actgggagca ctgctgggct cctggactga gaatagttga acaccggggg 9100

 ctttgtgaag gagtctgggc caaggtttgc cctcagcttt gcagaatgaa 9150

 gccttgaggt ctgtcaccac ccacagccac cctacagcag ccttaactgt 9200

 gacacttgcc acactgtgtc gtcgtttgtt tgcctatgtt ctccagggca 9250

 cggtggcagg aacaactatc ctcgtctgtc ccaacactga gcaggcactc 9300

 ggtaaacacg aatgaatgga taagcgcacg gatgaatgga gcttacaaga 9350

 tctgtctttc caatggccgg gggcatttgg tccccaaatt aaggctattg 9400

 gacatctgca caggacagtc ctatttttga tgtcctttcc tttctgaaaa 9450

 taaagttttg tgctttggag aatgactcgt gagcacatct ttagggacca 9500

 agagtgactt tctgtaagga gtgactcgtg gcttgccttg gtctcttggg 9550

 aatacttttc taactagggt tgctctcacc tgagacattc tccacccgcg 9600

 gaatctcagg gtcccaggct gtgggccatc acgacctcaa actggctcct 9650

 aatctccagc tttcctgtca ttgaaagctt cggaagttta ctggctctgc 9700

 tcccgcctgt tttctttctg actctatctg gcagcccgat gccacccagt 9750

 acaggaagtg acaccagtac tctgtaaagc atcatcatcc ttggagagac 9800

 tgagcactca gcaccttcag ccacgatttc aggatcgctt ccttgtgagc 9850

 cgctgcctcc gaaatctcct ttgaagccca gacatctttc tccagcttca 9900

 gacttgtaga tataactcgt tcatcttcat ttactttcca ctttgccccc 9950

 tgtcctctct gtgttcccca aatcagagaa tagcccgcca tcccccagat 10000

 cacctgtctg gattcctccc cattcaccca ccttgccagg tgcaggtgag 10050

 gatggtgcac cagacagggt agctgtcccc caaaatgtgc cctgtgcggg 10100

 cagtgccctg tctccacgtt tgtttcccca gtgtctggcg gggagccagg 10150

 tgacatcata aatacttgct gaatgaatgc agaaatcagc ggtactgact 10200

 tgtactatat tggctgccat gatagggttc tcacagcgtc atccatgatc 10250

 gtaagggaga atgacattct gcttgaggga gggaatagaa aggggcaggg 10300

 aggggacatc tgagggcttc acagggctgc aaagggtaca gggattgcac 10350

 cagggcagaa caggggaggg tgttcaagga agagtggctc ttagcagagg 10400

 cactttggaa ggtgtgaggc ataaatgctt ccttctacgt aggccaacct 10450

 caaaactttc agtaggaatg ttgctatgat caagttgttc taacacttta 10500

 gacttagtag taattatgaa cctcacatag aaaaatttca tccagccata 10550

 tgcctgtgga gtggaatatt ctgtttagta gaaaaatcct ttagagttca 10600

 gctctaacca gaaatcttgc tgaagtatgt cagcaccttt tctcaccctg 10650

 gtaagtacag tatttcaaga gcacgctaag ggtggttttc attttacagg 10700

 gctgttgatg atgggttaaa aatgttcatt taagggctac ccccgtgttt 10750

 aatagatgaa caccacttct acacaaccct ccttggtact gggggaggga 10800

 gagatctgac aaatactgcc cattccccta ggctgactgg atttgagaac 10850

 aaatacccac ccatttccac catggtatgg taacttctct gagcttcagt 10900

 ttccaagtga atttccatgt aataggacat tcccattaaa tacaagctgt 10950

 ttttactttt tcgcctccca gggcctgtgc gatctggtcc cccagcctct 11000

 cttgggcttt cttacactaa ctctgtacct accatctcct gcctccctta 11050

 ggcaggcacc tccaaccacc acacactccc tgctgttttc cctgcctgga 11100

 actttcccac cagccccacc aagatcattt catccagtcc tgagctcagc 11150

 ttaagggagg cttcttgcct gtgggttccc tcacccccat gcctgtcctc 11200

 caggctgggg caggttctta gtttgcctgg aattgttctg tacctctttg 11250

 tagcacgtag tgttgtgaaa ctaagccact aattgagttt ctggctcccc 11300

 tcctggggtt gtaagttttg ttcattcatg agggccgact gtatttcctg 11350

 gttactgtat cccagtgacc agccacagga gatgtccaat aaagtatgtg 11400

 atgaaatggt cttaaaaaaa aaaaaaaaaa aaaaa 11435

<210> 2501
<211> 2896
<212> PRT
<213> Homo sapien

<400> 2501
 Met Trp Pro Thr Arg Arg Leu Val Thr Ile Lys Arg Ser Gly Val
   1               5                  10                  15

 Asp Gly Pro His Phe Pro Leu Ser Leu Ser Thr Cys Leu Phe Gly
                  20                  25                  30

 Arg Gly Ile Glu Cys Asp Ile Arg Ile Gln Leu Pro Val Val Ser
                  35                  40                  45

 Lys Gln His Cys Lys Ile Glu Ile His Glu Gln Glu Ala Ile Leu
                  50                  55                  60

 His Asn Phe Ser Ser Thr Asn Pro Thr Gln Val Asn Gly Ser Val
                  65                  70                  75

 Ile Asp Glu Pro Val Arg Leu Lys His Gly Asp Val Ile Thr Ile
                  80                  85                  90

 Ile Asp Arg Ser Phe Arg Tyr Glu Asn Glu Ser Leu Gln Asn Gly
                  95                 100                 105

 Arg Lys Ser Thr Glu Phe Pro Arg Lys Ile Arg Glu Gln Glu Pro
                 110                 115                 120

 Ala Arg Arg Val Ser Arg Ser Ser Phe Ser Ser Asp Pro Asp Glu
                 125                 130                 135

 Ser Glu Gly Ile Pro Leu Lys Arg Arg Arg Val Ser Phe Gly Gly
                 140                 145                 150

 His Leu Arg Pro Glu Leu Phe Asp Glu Asn Leu Pro Pro Asn Thr
                 155                 160                 165

 Pro Leu Lys Arg Gly Glu Ala Pro Thr Lys Arg Lys Ser Leu Val
                 170                 175                 180

 Met His Thr Pro Pro Val Leu Lys Lys Ile Ile Lys Glu Gln Pro
                 185                 190                 195

 Gln Pro Ser Gly Lys Gln Glu Ser Gly Ser Glu Ile His Val Glu
                 200                 205                 210

 Val Lys Ala Gln Ser Leu Val Ile Ser Pro Pro Ala Pro Ser Pro
                 215                 220                 225

 Arg Lys Thr Pro Val Ala Ser Asp Gln Arg Arg Arg Ser Cys Lys
                 230                 235                 240

 Thr Ala Pro Ala Ser Ser Ser Lys Ser Gln Thr Glu Val Pro Lys
                 245                 250                 255

 Arg Gly Gly Glu Arg Val Ala Thr Cys Leu Gln Lys Arg Val Ser
                 260                 265                 270

 Ile Ser Arg Ser Gln His Asp Ile Leu Gln Met Ile Cys Ser Lys
                 275                 280                 285

 Arg Arg Ser Gly Ala Ser Glu Ala Asn Leu Ile Val Ala Lys Ser
                 290                 295                 300

 Trp Ala Asp Val Val Lys Leu Gly Ala Lys Gln Thr Gln Thr Lys
                 305                 310                 315

 Val Ile Lys His Gly Pro Gln Arg Ser Met Asn Lys Arg Gln Arg
                 320                 325                 330

 Arg Pro Ala Thr Pro Lys Lys Pro Val Gly Glu Val His Ser Gln
                 335                 340                 345

 Phe Ser Thr Gly His Ala Asn Ser Pro Cys Thr Ile Ile Ile Gly
                 350                 355                 360

 Lys Ala His Thr Glu Lys Val His Val Pro Ala Arg Pro Tyr Arg
                 365                 370                 375

 Val Leu Asn Asn Phe Ile Ser Asn Gln Lys Met Asp Phe Lys Glu
                 380                 385                 390

 Asp Leu Ser Gly Ile Ala Glu Met Phe Lys Thr Pro Val Lys Glu
                 395                 400                 405

 Gln Pro Gln Leu Thr Ser Thr Cys His Ile Ala Ile Ser Asn Ser
                 410                 415                 420

 Glu Asn Leu Leu Gly Lys Gln Phe Gln Gly Thr Asp Ser Gly Glu
                 425                 430                 435

 Glu Pro Leu Leu Pro Thr Ser Glu Ser Phe Gly Gly Asn Val Phe
                 440                 445                 450

 Phe Ser Ala Gln Asn Ala Ala Lys Gln Pro Ser Asp Lys Cys Ser
                 455                 460                 465

 Ala Ser Pro Pro Leu Arg Arg Gln Cys Ile Arg Glu Asn Gly Asn
                 470                 475                 480

 Val Ala Lys Thr Pro Arg Asn Thr Tyr Lys Met Thr Ser Leu Glu
                 485                 490                 495

 Thr Lys Thr Ser Asp Thr Glu Thr Glu Pro Ser Lys Thr Val Ser
                 500                 505                 510

 Thr Val Asn Arg Ser Gly Arg Ser Thr Glu Phe Arg Asn Ile Gln
                 515                 520                 525

 Lys Leu Pro Val Glu Ser Lys Ser Glu Glu Thr Asn Thr Glu Ile
                 530                 535                 540

 Val Glu Cys Ile Leu Lys Arg Gly Gln Lys Ala Thr Leu Leu Gln
                 545                 550                 555

 Gln Arg Arg Glu Gly Glu Met Lys Glu Ile Glu Arg Pro Phe Glu
                 560                 565                 570

 Thr Tyr Lys Glu Asn Ile Glu Leu Lys Glu Asn Asp Glu Lys Met
                 575                 580                 585

 Lys Ala Met Lys Arg Ser Arg Thr Trp Gly Gln Lys Cys Ala Pro
                 590                 595                 600

 Met Ser Asp Leu Thr Asp Leu Lys Ser Leu Pro Asp Thr Glu Leu
                 605                 610                 615

 Met Lys Asp Thr Ala Arg Gly Gln Asn Leu Leu Gln Thr Gln Asp
                 620                 625                 630

 His Ala Lys Ala Pro Lys Ser Glu Lys Gly Lys Ile Thr Lys Met
                 635                 640                 645

 Pro Cys Gln Ser Leu Gln Pro Glu Pro Ile Asn Thr Pro Thr His
                 650                 655                 660

 Thr Lys Gln Gln Leu Lys Ala Ser Leu Gly Lys Val Gly Val Lys
                 665                 670                 675

 Glu Glu Leu Leu Ala Val Gly Lys Phe Thr Arg Thr Ser Gly Glu
                 680                 685                 690

 Thr Thr His Thr His Arg Glu Pro Ala Gly Asp Gly Lys Ser Ile
                 695                 700                 705

 Arg Thr Phe Lys Glu Ser Pro Lys Gln Ile Leu Asp Pro Ala Ala
                 710                 715                 720

 Arg Val Thr Gly Met Lys Lys Trp Pro Arg Thr Pro Lys Glu Glu
                 725                 730                 735

 Ala Gln Ser Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln
                 740                 745                 750

 Thr Pro Gly Pro Ser Glu Glu Ser Met Thr Asp Glu Lys Thr Thr
                 755                 760                 765

 Lys Ile Ala Cys Lys Ser Pro Pro Pro Glu Ser Val Asp Thr Pro
                 770                 775                 780

 Thr Ser Thr Lys Gln Trp Pro Lys Arg Ser Leu Arg Lys Ala Asp
                 785                 790                 795

 Val Glu Glu Glu Phe Leu Ala Leu Arg Lys Leu Thr Pro Ser Ala
                 800                 805                 810

 Gly Lys Ala Met Leu Thr Pro Lys Pro Ala Gly Gly Asp Glu Lys
                 815                 820                 825

 Asp Ile Lys Ala Phe Met Gly Thr Pro Val Gln Lys Leu Asp Leu
                 830                 835                 840

 Ala Gly Thr Leu Pro Gly Ser Lys Arg Gln Leu Gln Thr Pro Lys
                 845                 850                 855

 Glu Lys Ala Gln Ala Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu
                 860                 865                 870

 Phe Gln Thr Pro Gly His Thr Glu Glu Leu Val Ala Ala Gly Lys
                 875                 880                 885

 Thr Thr Lys Ile Pro Cys Asp Ser Pro Gln Ser Asp Pro Val Asp
                 890                 895                 900

 Thr Pro Thr Ser Thr Lys Gln Arg Pro Lys Arg Ser Ile Arg Lys
                 905                 910                 915

 Ala Asp Val Glu Gly Glu Leu Leu Ala Cys Arg Asn Leu Met Pro
                 920                 925                 930

 Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ser Val Gly Glu
                 935                 940                 945

 Glu Lys Asp Ile Ile Ile Phe Val Gly Thr Pro Val Gln Lys Leu
                 950                 955                 960

 Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Pro Gln Thr
                 965                 970                 975

 Pro Lys Glu Glu Ala Gln Ala Leu Glu Asp Leu Thr Gly Phe Lys
                 980                 985                 990

 Glu Leu Phe Gln Thr Pro Gly His Thr Glu Glu Ala Val Ala Ala
                 995                1000                1005

 Gly Lys Thr Thr Lys Met Pro Cys Glu Ser Ser Pro Pro Glu Ser
                1010                1015                1020

 Ala Asp Thr Pro Thr Ser Thr Arg Arg Gln Pro Lys Thr Pro Leu
                1025                1030                1035

 Glu Lys Arg Asp Val Gln Lys Glu Leu Ser Ala Leu Lys Lys Leu
                1040                1045                1050

 Thr Gln Thr Ser Gly Glu Thr Thr His Thr Asp Lys Val Pro Gly
                1055                1060                1065

 Gly Glu Asp Lys Ser Ile Asn Ala Phe Arg Glu Thr Ala Lys Gln
                1070                1075                1080

 Lys Leu Asp Pro Ala Ala Ser Val Thr Gly Ser Lys Arg His Pro
                1085                1090                1095

 Lys Thr Lys Glu Lys Ala Gln Pro Leu Glu Asp Leu Ala Gly Trp
                1100                1105                1110

 Lys Glu Leu Phe Gln Thr Pro Val Cys Thr Asp Lys Pro Thr Thr
                1115                1120                1125

 His Glu Lys Thr Thr Lys Ile Ala Cys Arg Ser Gln Pro Asp Pro
                1130                1135                1140

 Val Asp Thr Pro Thr Ser Ser Lys Pro Gln Ser Lys Arg Ser Leu
                1145                1150                1155

 Arg Lys Val Asp Val Glu Glu Glu Phe Phe Ala Leu Arg Lys Arg
                1160                1165                1170

 Thr Pro Ser Ala Gly Lys Ala Met His Thr Pro Lys Pro Ala Val
                1175                1180                1185

 Ser Gly Glu Lys Asn Ile Tyr Ala Phe Met Gly Thr Pro Val Gln
                1190                1195                1200

 Lys Leu Asp Leu Thr Glu Asn Leu Thr Gly Ser Lys Arg Arg Leu
                1205                1210                1215

 Gln Thr Pro Lys Glu Lys Ala Gln Ala Leu Glu Asp Leu Ala Gly
                1220                1225                1230

 Phe Lys Glu Leu Phe Gln Thr Arg Gly His Thr Glu Glu Ser Met
                1235                1240                1245

 Thr Asn Asp Lys Thr Ala Lys Val Ala Cys Lys Ser Ser Gln Pro
                1250                1255                1260

 Asp Leu Asp Lys Asn Pro Ala Ser Ser Lys Arg Arg Leu Lys Thr
                1265                1270                1275

 Ser Leu Gly Lys Val Gly Val Lys Glu Glu Leu Leu Ala Val Gly
                1280                1285                1290

 Lys Leu Thr Gln Thr Ser Gly Glu Thr Thr His Thr His Thr Glu
                1295                1300                1305

 Pro Thr Gly Asp Gly Lys Ser Met Lys Ala Phe Met Glu Ser Pro
                1310                1315                1320

 Lys Gln Ile Leu Asp Ser Ala Ala Ser Leu Thr Gly Ser Lys Arg
                1325                1330                1335

 Gln Leu Arg Thr Pro Lys Gly Lys Ser Glu Val Pro Glu Asp Leu
                1340                1345                1350

 Ala Gly Phe Ile Glu Leu Phe Gln Thr Pro Ser His Thr Lys Glu
                1355                1360                1365

 Ser Met Thr Asn Glu Lys Thr Thr Lys Val Ser Tyr Arg Ala Ser
                1370                1375                1380

 Gln Pro Asp Leu Val Asp Thr Pro Thr Ser Ser Lys Pro Gln Pro
                1385                1390                1395

 Lys Arg Ser Leu Arg Lys Ala Asp Thr Glu Glu Glu Phe Leu Ala
                1400                1405                1410

 Phe Arg Lys Gln Thr Pro Ser Ala Gly Lys Ala Met His Thr Pro
                1415                1420                1425

 Lys Pro Ala Val Gly Glu Glu Lys Asp Ile Asn Thr Phe Leu Gly
                1430                1435                1440

 Thr Pro Val Gln Lys Leu Asp Gln Pro Gly Asn Leu Pro Gly Ser
                1445                1450                1455

 Asn Arg Arg Leu Gln Thr Arg Lys Glu Lys Ala Gln Ala Leu Glu
                1460                1465                1470

 Glu Leu Thr Gly Phe Arg Glu Leu Phe Gln Thr Pro Cys Thr Asp
                1475                1480                1485

 Asn Pro Thr Ala Asp Glu Lys Thr Thr Lys Lys Ile Leu Cys Lys
                1490                1495                1500

 Ser Pro Gln Ser Asp Pro Ala Asp Thr Pro Thr Asn Thr Lys Gln
                1505                1510                1515

 Arg Pro Lys Arg Ser Leu Lys Lys Ala Asp Val Glu Glu Glu Phe
                1520                1525                1530

 Leu Ala Phe Arg Lys Leu Thr Pro Ser Ala Gly Lys Ala Met His
                1535                1540                1545

 Thr Pro Lys Ala Ala Val Gly Glu Glu Lys Asp Ile Asn Thr Phe
                1550                1555                1560

 Val Gly Thr Pro Val Glu Lys Leu Asp Leu Leu Gly Asn Leu Pro
                1565                1570                1575

 Gly Ser Lys Arg Arg Pro Gln Thr Pro Lys Glu Lys Ala Lys Ala
                1580                1585                1590

 Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr Pro Gly
                1595                1600                1605

 His Thr Glu Glu Ser Met Thr Asp Asp Lys Ile Thr Glu Val Ser
                1610                1615                1620

 Cys Lys Ser Pro Gln Pro Asp Pro Val Lys Thr Pro Thr Ser Ser
                1625                1630                1635

 Lys Gln Arg Leu Lys Ile Ser Leu Gly Lys Val Gly Val Lys Glu
                1640                1645                1650

 Glu Val Leu Pro Val Gly Lys Leu Thr Gln Thr Ser Gly Lys Thr
                1655                1660                1665

 Thr Gln Thr His Arg Glu Thr Ala Gly Asp Gly Lys Ser Ile Lys
                1670                1675                1680

 Ala Phe Lys Glu Ser Ala Lys Gln Met Leu Asp Pro Ala Asn Tyr
                1685                1690                1695

 Gly Thr Gly Met Glu Arg Trp Pro Arg Thr Pro Lys Glu Glu Ala
                1700                1705                1710

 Gln Ser Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr
                1715                1720                1725

 Pro Asp His Thr Glu Glu Ser Thr Thr Asp Asp Lys Thr Thr Lys
                1730                1735                1740

 Ile Ala Cys Lys Ser Pro Pro Pro Glu Ser Met Asp Thr Pro Thr
                1745                1750                1755

 Ser Thr Arg Arg Arg Pro Lys Thr Pro Leu Gly Lys Arg Asp Ile
                1760                1765                1770

 Val Glu Glu Leu Ser Ala Leu Lys Gln Leu Thr Gln Thr Thr His
                1775                1780                1785

 Thr Asp Lys Val Pro Gly Asp Glu Asp Lys Gly Ile Asn Val Phe
                1790                1795                1800

 Arg Glu Thr Ala Lys Gln Lys Leu Asp Pro Ala Ala Ser Val Thr
                1805                1810                1815

 Gly Ser Lys Arg Gln Pro Arg Thr Pro Lys Gly Lys Ala Gln Pro
                1820                1825                1830

 Leu Glu Asp Leu Ala Gly Leu Lys Glu Leu Phe Gln Thr Pro Val
                1835                1840                1845

 Cys Thr Asp Lys Pro Thr Thr His Glu Lys Thr Thr Lys Ile Ala
                1850                1855                1860

 Cys Arg Ser Pro Gln Pro Asp Pro Val Gly Thr Pro Thr Ile Phe
                1865                1870                1875

 Lys Pro Gln Ser Lys Arg Ser Leu Arg Lys Ala Asp Val Glu Glu
                1880                1885                1890

 Glu Ser Leu Ala Leu Arg Lys Arg Thr Pro Ser Val Gly Lys Ala
                1895                1900                1905

 Met Asp Thr Pro Lys Pro Ala Gly Gly Asp Glu Lys Asp Met Lys
                1910                1915                1920

 Ala Phe Met Gly Thr Pro Val Gln Lys Leu Asp Leu Pro Gly Asn
                1925                1930                1935

 Leu Pro Gly Ser Lys Arg Trp Pro Gln Thr Pro Lys Glu Lys Ala
                1940                1945                1950

 Gln Ala Leu Glu Asp Leu Ala Gly Phe Lys Glu Leu Phe Gln Thr
                1955                1960                1965

 Pro Gly Thr Asp Lys Pro Thr Thr Asp Glu Lys Thr Thr Lys Ile
                1970                1975                1980

 Ala Cys Lys Ser Pro Gln Pro Asp Pro Val Asp Thr Pro Ala Ser
                1985                1990                1995

 Thr Lys Gln Arg Pro Lys Arg Asn Leu Arg Lys Ala Asp Val Glu
                2000                2005                2010

 Glu Glu Phe Leu Ala Leu Arg Lys Arg Thr Pro Ser Ala Gly Lys
                2015                2020                2025

 Ala Met Asp Thr Pro Lys Pro Ala Val Ser Asp Glu Lys Asn Ile
                2030                2035                2040

 Asn Thr Phe Val Glu Thr Pro Val Gln Lys Leu Asp Leu Leu Gly
                2045                2050                2055

 Asn Leu Pro Gly Ser Lys Arg Gln Pro Gln Thr Pro Lys Glu Lys
                2060                2065                2070

 Ala Glu Ala Leu Glu Asp Leu Val Gly Phe Lys Glu Leu Phe Gln
                2075                2080                2085

 Thr Pro Gly His Thr Glu Glu Ser Met Thr Asp Asp Lys Ile Thr
                2090                2095                2100

 Glu Val Ser Cys Lys Ser Pro Gln Pro Glu Ser Phe Lys Thr Ser
                2105                2110                2115

 Arg Ser Ser Lys Gln Arg Leu Lys Ile Pro Leu Val Lys Val Asp
                2120                2125                2130

 Met Lys Glu Glu Pro Leu Ala Val Ser Lys Leu Thr Arg Thr Ser
                2135                2140                2145

 Gly Glu Thr Thr Gln Thr His Thr Glu Pro Thr Gly Asp Ser Lys
                2150                2155                2160

 Ser Ile Lys Ala Phe Lys Glu Ser Pro Lys Gln Ile Leu Asp Pro
                2165                2170                2175

 Ala Ala Ser Val Thr Gly Ser Arg Arg Gln Leu Arg Thr Arg Lys
                2180                2185                2190

 Glu Lys Ala Arg Ala Leu Glu Asp Leu Val Asp Phe Lys Glu Leu
                2195                2200                2205

 Phe Ser Ala Pro Gly His Thr Glu Glu Ser Met Thr Ile Asp Lys
                2210                2215                2220

 Asn Thr Lys Ile Pro Cys Lys Ser Pro Pro Pro Glu Leu Thr Asp
                2225                2230                2235

 Thr Ala Thr Ser Thr Lys Arg Cys Pro Lys Thr Arg Pro Arg Lys
                2240                2245                2250

 Glu Val Lys Glu Glu Leu Ser Ala Val Glu Arg Leu Thr Gln Thr
                2255                2260                2265

 Ser Gly Gln Ser Thr His Thr His Lys Glu Pro Ala Ser Gly Asp
                2270                2275                2280

 Glu Gly Ile Lys Val Leu Lys Gln Arg Ala Lys Lys Lys Pro Asn
                2285                2290                2295

 Pro Val Glu Glu Glu Pro Ser Arg Arg Arg Pro Arg Ala Pro Lys
                2300                2305                2310

 Glu Lys Ala Gln Pro Leu Glu Asp Leu Ala Gly Phe Thr Glu Leu
                2315                2320                2325

 Ser Glu Thr Ser Gly His Thr Gln Glu Ser Leu Thr Ala Gly Lys
                2330                2335                2340

 Ala Thr Lys Ile Pro Cys Glu Ser Pro Pro Leu Glu Val Val Asp
                2345                2350                2355

 Thr Thr Ala Ser Thr Lys Arg His Leu Arg Thr Arg Val Gln Lys
                2360                2365                2370

 Val Gln Val Lys Glu Glu Pro Ser Ala Val Lys Phe Thr Gln Thr
                2375                2380                2385

 Ser Gly Glu Thr Thr Asp Ala Asp Lys Glu Pro Ala Gly Glu Asp
                2390                2395                2400

 Lys Gly Ile Lys Ala Leu Lys Glu Ser Ala Lys Gln Thr Pro Ala
                2405                2410                2415

 Pro Ala Ala Ser Val Thr Gly Ser Arg Arg Arg Pro Arg Ala Pro
                2420                2425                2430

 Arg Glu Ser Ala Gln Ala Ile Glu Asp Leu Ala Gly Phe Lys Asp
                2435                2440                2445

 Pro Ala Ala Gly His Thr Glu Glu Ser Met Thr Asp Asp Lys Thr
                2450                2455                2460

 Thr Lys Ile Pro Cys Lys Ser Ser Pro Glu Leu Glu Asp Thr Ala
                2465                2470                2475

 Thr Ser Ser Lys Arg Arg Pro Arg Thr Arg Ala Gln Lys Val Glu
                2480                2485                2490

 Val Lys Glu Glu Leu Leu Ala Val Gly Lys Leu Thr Gln Thr Ser
                2495                2500                2505

 Gly Glu Thr Thr His Thr Asp Lys Glu Pro Val Gly Glu Gly Lys
                2510                2515                2520

 Gly Thr Lys Ala Phe Lys Gln Pro Ala Lys Arg Asn Val Asp Ala
                2525                2530                2535

 Glu Asp Val Ile Gly Ser Arg Arg Gln Pro Arg Ala Pro Lys Glu
                2540                2545                2550

 Lys Ala Gln Pro Leu Glu Asp Leu Ala Ser Phe Gln Glu Leu Ser
                2555                2560                2565

 Gln Thr Pro Gly His Thr Glu Glu Leu Ala Asn Gly Ala Ala Asp
                2570                2575                2580

 Ser Phe Thr Ser Ala Pro Lys Gln Thr Pro Asp Ser Gly Lys Pro
                2585                2590                2595

 Leu Lys Ile Ser Arg Arg Val Leu Arg Ala Pro Lys Val Glu Pro
                2600                2605                2610

 Val Gly Asp Val Val Ser Thr Arg Asp Pro Val Lys Ser Gln Ser
                2615                2620                2625

 Lys Ser Asn Thr Ser Leu Pro Pro Leu Pro Phe Lys Arg Gly Gly
                2630                2635                2640

 Gly Lys Asp Gly Ser Val Thr Gly Thr Lys Arg Leu Arg Cys Met
                2645                2650                2655

 Pro Ala Pro Glu Glu Ile Val Glu Glu Leu Pro Ala Ser Lys Lys
                2660                2665                2670

 Gln Arg Val Ala Pro Arg Ala Arg Gly Lys Ser Ser Glu Pro Val
                2675                2680                2685

 Val Ile Met Lys Arg Ser Leu Arg Thr Ser Ala Lys Arg Ile Glu
                2690                2695                2700

 Pro Ala Glu Glu Leu Asn Ser Asn Asp Met Lys Thr Asn Lys Glu
                2705                2710                2715

 Glu His Lys Leu Gln Asp Ser Val Pro Glu Asn Lys Gly Ile Ser
                2720                2725                2730

 Leu Arg Ser Arg Arg Gln Asp Lys Thr Glu Ala Glu Gln Gln Ile
                2735                2740                2745

 Thr Glu Val Phe Val Leu Ala Glu Arg Ile Glu Ile Asn Arg Asn
                2750                2755                2760

 Glu Lys Lys Pro Met Lys Thr Ser Pro Glu Met Asp Ile Gln Asn
                2765                2770                2775

 Pro Asp Asp Gly Ala Arg Lys Pro Ile Pro Arg Asp Lys Val Thr
                2780                2785                2790

 Glu Asn Lys Arg Cys Leu Arg Ser Ala Arg Gln Asn Glu Ser Ser
                2795                2800                2805

 Gln Pro Lys Val Ala Glu Glu Ser Gly Gly Gln Lys Ser Ala Lys
                2810                2815                2820

 Val Leu Met Gln Asn Gln Lys Gly Lys Gly Glu Ala Gly Asn Ser
                2825                2830                2835

 Asp Ser Met Cys Leu Arg Ser Arg Lys Thr Lys Ser Gln Pro Ala
                2840                2845                2850

 Ala Ser Thr Leu Glu Ser Lys Ser Val Gln Arg Val Thr Arg Ser
                2855                2860                2865

 Val Lys Arg Cys Ala Glu Asn Pro Lys Lys Ala Glu Asp Asn Val
                2870                2875                2880

 Cys Val Lys Lys Ile Thr Thr Arg Ser His Arg Asp Ser Glu Asp
                2885                2890                2895

 Ile


<210> 2502
<211> 2379
<212> DNA
<213> Homo sapien

<400> 2502
 ggcacgaggg ggaagcaggg gtagcggagc catgggggac gctcccagcc 50

 ctgaagagaa actgcacctt atcacccgga acctgcagga ggttctgggg 100

 gaagagaagc tgaaggagat actgaaggag cgggaactta aaatttactg 150

 gggaacggca accacgggca aaccacatgt ggcttacttt gtgcccatgt 200

 caaagattgc agacttctta aaggcagggt gtgaggtaac aattctgttt 250

 gcggacctcc acgcatacct ggataacatg aaagccccat gggaacttct 300

 agaactccga gtcagttact atgagaatgt gatcaaagca atgctggaga 350

 gcattggtgt gcccttggag aagctcaagt tcatcaaagg cactgattac 400

 cagctcagca aagagtacac actagatgtg tacagactct cctccgtggt 450

 cacacagcac gattccaaga aggctggagc tgaggtggta aagcaggtgg 500

 agcacccttt gctgagtggc ctcttatacc ccggactgca ggctttggat 550

 gaagagtatt taaaagtaga tgcccaattt ggaggcattg atcagagaaa 600

 gattttcacc tttgcagaga agtacctccc tgcacttggc tattcaaaac 650

 gggtccatct gatgaatcct atggttccag gattaacagg cagcaaaatg 700

 agctcttcag aagaggagtc caagattgat ctccttgatc ggaaggagga 750

 tgtgaagaaa aaactgaaga aggccttctg tgagccagga aatgtggaga 800

 acaatggggt tctgtccttc atcaagcatg tcctttttcc ccttaagtcc 850

 gagtttgtga tcctacgaga tgagaaatgg ggtggaaaca aaacctacac 900

 agcttacgtg gacctggaaa aggactttgc tgctgaggtt gtacatcctg 950

 gagacctgaa gaattctgtt gaagtcgcac tgaacaagtt gctggatcca 1000

 atccgggaaa agtttaatac ccctgccctg aaaaaactgg ccagcgctgc 1050

 ctacccagat ccctcaaagc agaagccaat ggccaaaggc cctgccaaga 1100

 attcagaacc agaggaggtc atcccatccc ggctggatat ccgtgtgggg 1150

 aaaatcatca ctgtggagaa gcacccagat gcagacagcc tgtatgtaga 1200

 gaagattgac gtgggggaag ctgaaccacg gactgtggtg agcggcctgg 1250

 tacagttcgt gcccaaggag gaactgcagg acaggctggt agtggtgctg 1300

 tgcaacctga aaccccagaa gatgagagga gtcgagtccc aaggcatgct 1350

 tctgtgtgct tctatagaag ggataaaccg ccaggttgaa cctctggacc 1400

 ctccggcagg ctctgctcct ggtgagcacg tgtttgtgaa gggctatgaa 1450

 aagggccaac cagatgagga gctcaagccc aagaagaaag tcttcgagaa 1500

 gttgcaggct gacttcaaaa tttctgagga gtgcatcgca cagtggaagc 1550

 aaaccaactt catgaccaag ctgggctcca tttcctgtaa atcgctgaaa 1600

 ggggggaaca ttagctagcc agcccagcat cttcccccct tcttccacca 1650

 ctgagtcatc tgctgtctct tcagtctgct ccatccatca cccatttacc 1700

 catctctcag gacacggaag cagcgggttt ggactcttta ttcggtgcag 1750

 aactcggcaa ggggcagctt accctcccca gaacccagga tcatcctgtc 1800

 tggctgcagt gagagaccaa cccctaacaa gggctgggcc acagcaggga 1850

 gtccagccct accttcttcc cttggcagct ggagaaatct ggtttcaata 1900

 taactcattt aaaaatttat gccacagtcc ttataattgg aaaaatactg 1950

 gtgcccaggt tttcttggag ttatccaagc agctgcgccc ctagctggga 2000

 tctggtacct ggactaggct aattacagct tctccccaac aggaaactgt 2050

 gggatttgaa aaggaaaggg aagggaaaac agagaaccta gtggtctacc 2100

 aagtggttgg caactttccc aatgtctgct tactctgagg cttggcactg 2150

 ggggccaggg cctgccccag ggctcctgga atttcccttg atccagctag 2200

 gctgggacac tccctaaatc agctgcgtgt tgttagcatc aggcagaatg 2250

 aatggcagag agtgattctg tcttcataga gggtggggta cttctccata 2300

 aggcatctca gtcaaatccc catcactgtc ataaattcaa ataaaatgtc 2350

 tgaacaaggg aaaaaaaaaa aaaaaaaaa 2379

<210> 2503
<211> 528
<212> PRT
<213> Homo sapien

<400> 2503
 Met Gly Asp Ala Pro Ser Pro Glu Glu Lys Leu His Leu Ile Thr
   1               5                  10                  15

 Arg Asn Leu Gln Glu Val Leu Gly Glu Glu Lys Leu Lys Glu Ile
                  20                  25                  30

 Leu Lys Glu Arg Glu Leu Lys Ile Tyr Trp Gly Thr Ala Thr Thr
                  35                  40                  45

 Gly Lys Pro His Val Ala Tyr Phe Val Pro Met Ser Lys Ile Ala
                  50                  55                  60

 Asp Phe Leu Lys Ala Gly Cys Glu Val Thr Ile Leu Phe Ala Asp
                  65                  70                  75

 Leu His Ala Tyr Leu Asp Asn Met Lys Ala Pro Trp Glu Leu Leu
                  80                  85                  90

 Glu Leu Arg Val Ser Tyr Tyr Glu Asn Val Ile Lys Ala Met Leu
                  95                 100                 105

 Glu Ser Ile Gly Val Pro Leu Glu Lys Leu Lys Phe Ile Lys Gly
                 110                 115                 120

 Thr Asp Tyr Gln Leu Ser Lys Glu Tyr Thr Leu Asp Val Tyr Arg
                 125                 130                 135

 Leu Ser Ser Val Val Thr Gln His Asp Ser Lys Lys Ala Gly Ala
                 140                 145                 150

 Glu Val Val Lys Gln Val Glu His Pro Leu Leu Ser Gly Leu Leu
                 155                 160                 165

 Tyr Pro Gly Leu Gln Ala Leu Asp Glu Glu Tyr Leu Lys Val Asp
                 170                 175                 180

 Ala Gln Phe Gly Gly Ile Asp Gln Arg Lys Ile Phe Thr Phe Ala
                 185                 190                 195

 Glu Lys Tyr Leu Pro Ala Leu Gly Tyr Ser Lys Arg Val His Leu
                 200                 205                 210

 Met Asn Pro Met Val Pro Gly Leu Thr Gly Ser Lys Met Ser Ser
                 215                 220                 225

 Ser Glu Glu Glu Ser Lys Ile Asp Leu Leu Asp Arg Lys Glu Asp
                 230                 235                 240

 Val Lys Lys Lys Leu Lys Lys Ala Phe Cys Glu Pro Gly Asn Val
                 245                 250                 255

 Glu Asn Asn Gly Val Leu Ser Phe Ile Lys His Val Leu Phe Pro
                 260                 265                 270

 Leu Lys Ser Glu Phe Val Ile Leu Arg Asp Glu Lys Trp Gly Gly
                 275                 280                 285

 Asn Lys Thr Tyr Thr Ala Tyr Val Asp Leu Glu Lys Asp Phe Ala
                 290                 295                 300

 Ala Glu Val Val His Pro Gly Asp Leu Lys Asn Ser Val Glu Val
                 305                 310                 315

 Ala Leu Asn Lys Leu Leu Asp Pro Ile Arg Glu Lys Phe Asn Thr
                 320                 325                 330

 Pro Ala Leu Lys Lys Leu Ala Ser Ala Ala Tyr Pro Asp Pro Ser
                 335                 340                 345

 Lys Gln Lys Pro Met Ala Lys Gly Pro Ala Lys Asn Ser Glu Pro
                 350                 355                 360

 Glu Glu Val Ile Pro Ser Arg Leu Asp Ile Arg Val Gly Lys Ile
                 365                 370                 375

 Ile Thr Val Glu Lys His Pro Asp Ala Asp Ser Leu Tyr Val Glu
                 380                 385                 390

 Lys Ile Asp Val Gly Glu Ala Glu Pro Arg Thr Val Val Ser Gly
                 395                 400                 405

 Leu Val Gln Phe Val Pro Lys Glu Glu Leu Gln Asp Arg Leu Val
                 410                 415                 420

 Val Val Leu Cys Asn Leu Lys Pro Gln Lys Met Arg Gly Val Glu
                 425                 430                 435

 Ser Gln Gly Met Leu Leu Cys Ala Ser Ile Glu Gly Ile Asn Arg
                 440                 445                 450

 Gln Val Glu Pro Leu Asp Pro Pro Ala Gly Ser Ala Pro Gly Glu
                 455                 460                 465

 His Val Phe Val Lys Gly Tyr Glu Lys Gly Gln Pro Asp Glu Glu
                 470                 475                 480

 Leu Lys Pro Lys Lys Lys Val Phe Glu Lys Leu Gln Ala Asp Phe
                 485                 490                 495

 Lys Ile Ser Glu Glu Cys Ile Ala Gln Trp Lys Gln Thr Asn Phe
                 500                 505                 510

 Met Thr Lys Leu Gly Ser Ile Ser Cys Lys Ser Leu Lys Gly Gly
                 515                 520                 525

 Asn Ile Ser


<210> 2504
<211> 4368
<212> DNA
<213> Homo sapien

<400> 2504
 cttcgctcgc tccctccctc cgtcttaggt cactgttttc aacctcgaat 50

 aaaaactgca gccaacttcc gaggcagcct cattgcccag cggaccccag 100

 cctctgccag gttcggtccg ccatcctcgt cccgtcctcc gccggcccct 150

 gccccgcgcc cagggatcct ccagctcctt tcgcccgcgc cctccgttcg 200

 ctccggacac catggacaag ttttggtggc acgcagcctg gggactctgc 250

 ctcgtgccgc tgagcctggc gcagatcgat ttgaatataa cctgccgctt 300

 tgcaggtgta ttccacgtgg agaaaaatgg tcgctacagc atctctcgga 350

 cggaggccgc tgacctctgc aaggctttca atagcacctt gcccacaatg 400

 gcccagatgg agaaagctct gagcatcgga tttgagacct gcaggtatgg 450

 gttcatagaa gggcatgtgg tgattccccg gatccacccc aactccatct 500

 gtgcagcaaa caacacaggg gtgtacatcc tcacatccaa cacctcccag 550

 tatgacacat attgcttcaa tgcttcagct ccacctgaag aagattgtac 600

 atcagtcaca gacctgccca atgcctttga tggaccaatt accataacta 650

 ttgttaaccg tgatggcacc cgctatgtcc agaaaggaga atacagaacg 700

 aatcctgaag acatctaccc cagcaaccct actgatgatg acgtgagcag 750

 cggctcctcc agtgaaagga gcagcacttc aggaggttac atcttttaca 800

 ccttttctac tgtacacccc atcccagacg aagacagtcc ctggatcacc 850

 gacagcacag acagaatccc tgctaccaga gaccaagaca cattccaccc 900

 cagtgggggg tcccatacca ctcatggatc tgaatcagat ggacactcac 950

 atgggagtca agaaggtgga gcaaacacaa cctctggtcc tataaggaca 1000

 ccccaaattc cagaatggct gatcatcttg gcatccctct tggccttggc 1050

 tttgattctt gcagtttgca ttgcagtcaa cagtcgaaga aggtgtgggc 1100

 agaagaaaaa gctagtgatc aacagtggca atggagctgt ggaggacaga 1150

 aagccaagtg gactcaacgg agaggccagc aagtctcagg aaatggtgca 1200

 tttggtgaac aaggagtcgt cagaaactcc agaccagttt atgacagctg 1250

 atgagacaag gaacctgcag aatgtggaca tgaagattgg ggtgtaacac 1300

 ctacaccatt atcttggaaa gaaacaaccg ttggaaacat aaccattaca 1350

 gggagctggg acacttaaca gatgcaatgt gctactgatt gtttcattgc 1400

 gaatcttttt tagcataaaa ttttctactc tttttgtttt ttgtgttttg 1450

 ttctttaaag tcaggtccaa tttgtaaaaa cagcattgct ttctgaaatt 1500

 agggcccaat taataatcag caagaatttg atcgttccag ttcccacttg 1550

 gaggcctttc atccctcggg tgtgctatgg atggcttcta acaaaaacta 1600

 cacatatgta ttcctgatcg ccaacctttc ccccaccagc taaggacatt 1650

 tcccagggtt aatagggcct ggtccctggg aggaaatttg aatgggtcca 1700

 ttttgccctt ccatagccta atccctgggc attgctttcc actgaggttg 1750

 ggggttgggg tgtactagtt acacatcttc aacagacccc ctctagaaat 1800

 ttttcagatg cttctgggag acacccaaag ggtgaagcta tttatctgta 1850

 gtaaactatt tatctgtgtt tttgaaatat taaaccctgg atcagtcctt 1900

 tgatcagtat aattttttaa agttactttg tcagaggcac aaaagggttt 1950

 aaactgattc ataataaata tctgtacttc ttcgatcttc accttttgtg 2000

 ctgtgattct tcagtttcta aaccagcact gtctgggtcc ctacaatgta 2050

 tcaggaagag ctgagaatgg taaggagact cttctaagtc ttcatctcag 2100

 agaccctgag ttcccactca gacccactca gccaaatctc atggaagacc 2150

 aaggagggca gcactgtttt tgttttttgt tttttgtttt ttttattttg 2200

 tgacactgtc caaaggtttt ccatcctgtc ctggaatcag agttggaagc 2250

 tgaggagctt cagcctcttt tatggtttaa tggccacctg ttctctcctg 2300

 tgaaaggctt tgcaaagtca cattaagttt gcatgacctg ttatccctgg 2350

 ggccctattt catagaggct ggccctatta gtgatttcca aaaacaatat 2400

 ggaagtgcct tttgatgtct tacaataaga gaagaagcca atggaaatga 2450

 aagagattgg caaaggggaa ggatgatgcc atgtagatcc tgtttgacat 2500

 ttttatggct gtatttgtaa acttaaacac accagtgtct gttcttgatg 2550

 cagttgctat ttaggatgag ttaagtgcct ggggagtccc tcaaaaggtt 2600

 aaagggattc ccatcattgg aatcttatca ccagataggc aagtttatga 2650

 ccaaacaaga gagtactggc tttatcctct aacctcatat tttctcccac 2700

 ttggcaagtc ctttgtggca tttattcatc agtcagggtg tccgattggt 2750

 cctagaactt ccaaaggctg cttgtcatag aagccattgc atctataaag 2800

 caacggctcc tgttaaatgg tatctccttt ctgaggctcc tactaaaagt 2850

 catttgttac ctaaacttat gtgcttaaca ggcaatgctt ctcagaccac 2900

 aaagcagaaa gaagaagaaa agctcctgac taaatcaggg ctgggcttag 2950

 acagagttga tctgtagaat atctttaaag gagagatgtc aactttctgc 3000

 actattccca gcctctgctc ctccctgtct accctctccc ctccctctct 3050

 ccctccactt caccccacaa tcttgaaaaa cttcctttct cttctgtgaa 3100

 catcattggc cagatccatt ttcagtggtc tggatttctt tttattttct 3150

 tttcaacttg aaagaaactg gacattaggc cactatgtgt tgttactgcc 3200

 actagtgttc aagtgcctct tgttttccca gagatttcct gggtctgcca 3250

 gaggcccaga caggctcact caagctcttt aactgaaaag caacaagcca 3300

 ctccaggaca aggttcaaaa tggttacaac agcctctacc tgtcgcccca 3350

 gggagaaagg ggtagtgata caagtctcat agccagagat ggttttccac 3400

 tccttctaga tattcccaaa aagaggctga gacaggaggt tattttcaat 3450

 tttattttgg aattaaatac ttttttccct ttattactgt tgtagtccct 3500

 cacttggata tacctctgtt ttcacgatag aaataaggga ggtctagagc 3550

 ttttattcct tggccattgt caacggagag ctggccaagt cttcacaaac 3600

 ccttgcaaca ttgcctgaag tttatggaat aagatgtatt ctcactccct 3650

 tgatctcaag ggcgtaactc tggaagcaca gcttgactac acgtcatttt 3700

 taccaatgat tttcaggtga cctgggctaa gtcatttaaa ctgggtcttt 3750

 ataaaagtaa aaggccaaca tttaattatt ttgcaaagca acctaagagc 3800

 taaagatgta atttttcttg caattgtaaa tcttttgtgt ctcctgaaga 3850

 cttcccttaa aattagctct gagtgaaaaa tcaaaagaga caaaagacat 3900

 cttcgaatcc atatttcaag cctggtagaa ttggcttttc tagcagaacc 3950

 tttccaaaag ttttatattg agattcataa caacaccaag aattgatttt 4000

 gtagccaaca ttcattcaat actgttatat cagaggagta ggagagagga 4050

 aacatttgac ttatctggaa aagcaaaatg tacttaagaa taagaataac 4100

 atggtccatt cacctttatg ttatagatat gtctttgtgt aaatcatttg 4150

 ttttgagttt tcaaagaata gcccattgtt cattcttgtg ctgtacaatg 4200

 accactgtta ttgttacttt gacttttcag agcacaccct tcctctggtt 4250

 tttgtatatt tattgatgga tcaataataa tgaggaaagc atgatatgta 4300

 tattgctgag ttgaaagcac ttattggaaa atattaaaag gctaacatta 4350

 aaagactaaa ggaaacag 4368

<210> 2505
<211> 361
<212> PRT
<213> Homo sapien

<400> 2505
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val
   1               5                  10                  15

 Pro Leu Ser Leu Ala Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe
                  20                  25                  30

 Ala Gly Val Phe His Val Glu Lys Asn Gly Arg Tyr Ser Ile Ser
                  35                  40                  45

 Arg Thr Glu Ala Ala Asp Leu Cys Lys Ala Phe Asn Ser Thr Leu
                  50                  55                  60

 Pro Thr Met Ala Gln Met Glu Lys Ala Leu Ser Ile Gly Phe Glu
                  65                  70                  75

 Thr Cys Arg Tyr Gly Phe Ile Glu Gly His Val Val Ile Pro Arg
                  80                  85                  90

 Ile His Pro Asn Ser Ile Cys Ala Ala Asn Asn Thr Gly Val Tyr
                  95                 100                 105

 Ile Leu Thr Ser Asn Thr Ser Gln Tyr Asp Thr Tyr Cys Phe Asn
                 110                 115                 120

 Ala Ser Ala Pro Pro Glu Glu Asp Cys Thr Ser Val Thr Asp Leu
                 125                 130                 135

 Pro Asn Ala Phe Asp Gly Pro Ile Thr Ile Thr Ile Val Asn Arg
                 140                 145                 150

 Asp Gly Thr Arg Tyr Val Gln Lys Gly Glu Tyr Arg Thr Asn Pro
                 155                 160                 165

 Glu Asp Ile Tyr Pro Ser Asn Pro Thr Asp Asp Asp Val Ser Ser
                 170                 175                 180

 Gly Ser Ser Ser Glu Arg Ser Ser Thr Ser Gly Gly Tyr Ile Phe
                 185                 190                 195

 Tyr Thr Phe Ser Thr Val His Pro Ile Pro Asp Glu Asp Ser Pro
                 200                 205                 210

 Trp Ile Thr Asp Ser Thr Asp Arg Ile Pro Ala Thr Arg Asp Gln
                 215                 220                 225

 Asp Thr Phe His Pro Ser Gly Gly Ser His Thr Thr His Gly Ser
                 230                 235                 240

 Glu Ser Asp Gly His Ser His Gly Ser Gln Glu Gly Gly Ala Asn
                 245                 250                 255

 Thr Thr Ser Gly Pro Ile Arg Thr Pro Gln Ile Pro Glu Trp Leu
                 260                 265                 270

 Ile Ile Leu Ala Ser Leu Leu Ala Leu Ala Leu Ile Leu Ala Val
                 275                 280                 285

 Cys Ile Ala Val Asn Ser Arg Arg Arg Cys Gly Gln Lys Lys Lys
                 290                 295                 300

 Leu Val Ile Asn Ser Gly Asn Gly Ala Val Glu Asp Arg Lys Pro
                 305                 310                 315

 Ser Gly Leu Asn Gly Glu Ala Ser Lys Ser Gln Glu Met Val His
                 320                 325                 330

 Leu Val Asn Lys Glu Ser Ser Glu Thr Pro Asp Gln Phe Met Thr
                 335                 340                 345

 Ala Asp Glu Thr Arg Asn Leu Gln Asn Val Asp Met Lys Ile Gly
                 350                 355                 360

 Val


<210> 2506
<211> 11269
<212> DNA
<213> Homo sapien

<400> 2506
 attctcttgc tccccgcccc gtcgggatca gtcagtgtga tccgaagcgg 50

 gggagggggg gggcggcggc cgaacgatgt gcgagaactg cgcagacctg 100

 gtggaggtgt taaatgaaat atcagatgta gaaggtggtg atggactgca 150

 gctcagaaag gaacatactc tcaaaatatt tacttacatc aattcctgga 200

 cacagaggca atgtctatgc tgcttcaagg aatataagca tttggagatt 250

 tttaatcaag tagtgtgtgc acttattaac ttagtgattg cccaagttca 300

 agtgctccgg gaccagcttt gtaaacattg tactaccatt aacatagatt 350

 ccacgtggca agatgagagt aatcaagcag aagaaccact gaatatagat 400

 agagagtgta atgaaggaag tacagaaaga caaaaatcaa tagaaaaaaa 450

 atcaaactct acaagaattt gtaatctgac tgaggaggaa tcttcaaaga 500

 gttctgatcc ttttagttta tggagtacag atgagaagga aaaactctta 550

 ctatgtgtgg caaaaaattt ttcaaattca gtttccctta tatactgctt 600

 acaagcataa tactcaccct actattgagg atatatcaac tcaagaaagt 650

 aacatattag gggcattctg tgatatgaat gatgtagaag taccattgca 700

 tttgcttcgt tatgtatgtt tgttttgtgg gaaaaatggc ctttctctca 750

 tgaaggattg ctttgaatat ggaactcctg aaactttgcc atttcttata 800

 gcacatgcgt ttattacagt tgtgtctaat attagaatat ggctacatat 850

 tcccgctgtc atgcagcaca ttataccttt taggacctat gttattaggt 900

 atttatgcaa gctctcggat caggagttac gacagagtgc agctcgtaac 950

 atggctgact taatgtggag cacagtcaaa gaaccattgg atacaacatt 1000

 atgctttgat aaagaaagcc tagatcttgc atttaagtac tttatgtcac 1050

 ctactttgac tatgaggttg gctggattga gtcagataac aaatcaactc 1100

 cataccttca atgatgtgtg caataatgaa tcattagtat cggacacaga 1150

 aacgtccatt gcaaaagaac ttgcagactg gcttattagc aacaatgtgg 1200

 tggagcatat atttggacca aatttacata ttgagattat caaacagtgc 1250

 caagtgattt tgaatttttt ggcagcagaa gggcgactga gtactcaaca 1300

 tattgactgt atttgggctg cagcacagtt gaaacattgt agtcggtata 1350

 tacatgactt atttccttca ctcatcaaga atttggatcc cgtaccactt 1400

 agacatctac ttaatctggt ctcagctctt gagccaagtg ttcatactga 1450

 acagacactg tacttggcat ccatgttaat taaagcactg tggaataacg 1500

 cactagcagc taaggctcag ttatctaaac agagttcttt tgcatcttta 1550

 ttaaatacta atattcccat tggaaataag aaagaggaag aagagcttag 1600

 aagaacagct ccatcacctt ggtcacctgc agctagtcct caaagcagtg 1650

 ataatagcga tacacatcaa agtggaggta gtgacattga aatggatgag 1700

 caacttatta atagaaccaa acatgtgcaa caacgacttt cagacacaga 1750

 ggaatccatg cagggaagtt ctgacgaaac tgccaacagt ggtgaagatg 1800

 gaagcagtgg tcctggtagc agtagtgggc atagtgatgg atctagcaat 1850

 gaggttaatt ctagccacgc aagccagtca gctgggagcc ctggcagtga 1900

 ggtacagtca gaagacattg cagatattga agccctcaaa gaggaagatg 1950

 aagacgatga tcatggtcat aatcctccca aaagcagttg tggtacagat 2000

 cttcggaata gaaagttaga gagtcaagca ggcatttgcc tgggggactc 2050

 ccaaggcacg tcagaaagaa atgggacaag cagcggaaca ggaaaggacc 2100

 tggtttttaa cactgaatca ttgccatcag tagataatcg aatgcgaatg 2150

 ctggatgctt gttcacactc tgaagaccca gaacatgata tttcagggga 2200

 aatgaatgct actcatatag cacaagggtc tcaggagtct tgtatcacac 2250

 gaactgggga cttccttggg gagactattg ggaatgaatt atttaattgt 2300

 cgacaattta ttggtccaca gcatcaccac caccaccacc accatcacca 2350

 ccaccacgat gggcatatgg ttgatgatat gctaagtgca gatgatgtca 2400

 gttgtagtag ctcccaggtt agtgcaaaat cagaaaaaaa tatggctgat 2450

 tttgatggtg aagaatctgg atgtgaagag gagctagttc agattaattc 2500

 acatgcggaa ctgacatctc acctccaaca acatcttccc aatttagctt 2550

 ccatttacca tgaacatctt agtcaaggac ctgtagttca taaacatcaa 2600

 ttcaacagta atgctgttac agacattaat ttggataatg tttgcaagaa 2650

 aggaaatact ttgttgtggg atatagtcca agatgaagat gcagttaatc 2700

 tttctgaagg attaataaat gaagcagaga aacttctttg ttcgttagta 2750

 tgttggttta cagatagaca aattcgaatg agattcattg aaggttgcct 2800

 tgaaaacttg ggaaacaaca gatcagtagt aatttcactt cgtcttcttc 2850

 caaaactatt tggtactttt cagcagtttg ggagcagtta cgatacacac 2900

 tggataacaa tgtgggcaga aaaagaactg aacatgatga agcttttctt 2950

 tgataatttg gtatactaca ttcaaactgt gagagaagga agacaaaaac 3000

 atgcactgta cagccatagt gctgaagttc aagttcgtct tcaattcttg 3050

 acttgtgtat tttcaactct gggatcacct gatcatttca ggttaagttt 3100

 agagcaagtt gacatcttat ggcattgttt agtagaagat tctgaatgtt 3150

 atgatgatgc actccattgg tttttaaatc aagttcgaag taaagatcaa 3200

 catgctatgg gtatggaaac ctacaaacat cttttcctgg agaagatgcc 3250

 ccagctaaaa cctgaaacaa ttagcatgac tggcttaaac ctgtttcagc 3300

 atctctgtaa cttggctcga ttggctacca gtgcctatga tggttgttca 3350

 aattctgagc tgtgtggtat ggaccaattt tggggcattg ctttaagagc 3400

 acaatctggt gatgtcagtc gagcagctat ccagtatatt aactcctatt 3450

 atattaatgg taaaacaggt ttggagaagg agcaagaatt tattagtaag 3500

 tgcatggaga gtcttatgat agcttctagc agtcttgaac aggaatcaca 3550

 ctcaagtctc atggttatag aaagaggact ccttatgctg aagacacatc 3600

 tggaagcgtt taggagaagg tttgcatatc atctgagaca gtggcaaatt 3650

 gaaggcactg gtattagtag tcatttgaaa gcactgagtg acaaacagtc 3700

 tctgccgcta agggttgtat gccagccagc tggacttcct gacaagatga 3750

 ctattgaaat gtatcctagt gaccaggtag cagatcttag ggctgaagta 3800

 actcattggt atgaaaattt acagaaagaa caaataaatc aacaagctca 3850

 gcttcaggag tttggtcaaa gcaaccgaaa aggagagttt cctggaggcc 3900

 tcatgggacc tgtcaggatg atttcatctg gacacgagtt aacaacagat 3950

 tatgatgaaa aagcacttca tgagcttggt tttaaggata tgcagatggt 4000

 atttgtatct ttgggtgcac caaggagaga gcggaaaggg gaaggtgttc 4050

 agctgccagc atcttgcctc ccaccccctc agaaggacaa cattccaatg 4100

 cttttgcttt tacaagagcc tcatttaact actctttttg atttattaga 4150

 gatgcttgca tcatttaaac caccctcagg aaaagtggca gtggatgata 4200

 gtgagagctt acgatgtgaa gaacttcatc ttcatgcaga aaatctgtct 4250

 aggcgggtct gggagctact gatgcttctt cctacatgtc ctaatatgtt 4300

 gatggcattc cagaatatct cagatgagca gagtaatgat ggatttaatt 4350

 ggaaagaact tctcaaaatt aagagcgccc acaagctatt gtatgctctg 4400

 gaaattattg aagcactggg aaaacctaat agaagaataa ggagggagtc 4450

 tacgggaagt tacagtgatc tttatccaga ttcagatgat tcaagtgagg 4500

 atcaagtgga aaatagtaaa aattcctgga gttgcaagtt tgttgctgct 4550

 ggagggcttc aacagttatt agaaattttt aattctggaa ttctagagcc 4600

 taaagagcag gaatcatgga ctgtgtggca gctagactgt cttgcttgct 4650

 tgctgaagtt aatatgccag tttgcagtag atccatccga tttggattta 4700

 gcttatcatg atgtctttgc ctggtctggt atagcggaaa gccataggaa 4750

 aagaacctgg cctggcaaat caaggaaggc tgctggtgat catgctaagg 4800

 gtcttcatat accacgatta acagaggtat ttcttgttct tgtccaagga 4850

 accagtttga ttcagcgact tatgtctgtt gcttatacgt atgataatct 4900

 ggctcctaga gttttaaaag ctcagtctga tcacaggtct agacatgaag 4950

 tttcacatta ttcaatgtgg ctcttggtga gttgggctca ttgctgttct 5000

 ttagtgaaat ctagccttgc tgatagcgat catttacaag attggctaaa 5050

 gaaattgact ctccttattc ctgagactgc agttcgtcat gaatcatgca 5100

 gtggtctcta taagttatcc ctgtcagggc tggatggagg agactcaatc 5150

 aatcgttctt ttctgctatt ggctgcctca acattattga aatttcttcc 5200

 tgatgctcaa gcactcaaac ctattaggat agatgattat gaggaagaac 5250

 caatattaaa accaggatgt aaagagtatt tttggttgtt atgcaaatta 5300

 gttgacaaca tacatataaa ggacgctagt cagacaacgc tcctcgactt 5350

 agatgccttg gcaagacatt tggctgactg tattcgaagt agggagatcc 5400

 ttgatcatca ggatggtaat gtagaagatg atgggcttac aggactccta 5450

 aggcttgcaa caagtgttgt taaacacaaa ccacccttta aattttcaag 5500

 ggaaggacag gaatttttga gagatatctt caatctcctg tttttgttgc 5550

 caagtctaaa ggaccgacaa cagccaaagt gcaaatcaca ttcttcaaga 5600

 gctgccgctt acgatttgtt agtagagatg gtaaaggggt ctgttgagaa 5650

 ctacaggcta atacacaact gggttatggc acaacacatg cagtcccatg 5700

 caccttataa atgggattac tggcctcatg aagatgtccg tgctgaatgt 5750

 agatttgttg gccttactaa ccttggagct acttgttact tagcttctac 5800

 tattcagcaa ctttatatga tacctgaggc aagacaggct gtcttcactg 5850

 ccaagtattc agaggatatg aagcacaaga ccactcttct ggagcttcag 5900

 aaaatgttta catatttaat ggagagtgaa tgcaaagcat ataatcctag 5950

 acctttctgt aaaacataca ccatggataa gcagcctctg aatactgggg 6000

 aacagaaaga tatgacagag ttttttactg atctaattac caaaatcgaa 6050

 gaaatgtctc ccgaactgaa aaataccgtc aaaagtttat ttggaggtgt 6100

 aattacaaac aatgttgtat ccttggattg tgaacatgtt agtcaaactg 6150

 ctgaagagtt ttatactgtg aggtgccaag tggctgatat gaagaacatt 6200

 tatgaatctc ttgatgaagt tactataaaa gacactttgg aaggtgataa 6250

 catgtatact tgttctcatt gtgggaagaa agtacgagct gaaaaaaggg 6300

 catgttttaa gaaattgcct cgcattttga gtttcaatac tatgagatac 6350

 acatttaata tggtcacgat gatgaaagag aaagtgaata cacacttttc 6400

 cttcccatta cgtttggaca tgacgcccta tacagaagat tttcttatgg 6450

 gaaagagtga gaggaaagaa ggttttaaag aagtcagtga tcattcaaaa 6500

 gactcagaga gctatgaata tgacttgata ggagtgactg ttcacacagg 6550

 aacggcagat ggtggacact attatagctt tatcagagat atagtaaatc 6600

 cccatgctta taaaaacaat aaatggtatc tttttaatga tgctgaggta 6650

 aaaccttttg attctgctca acttgcatct gaatgttttg gtggagagat 6700

 gacgaccaag acctatgatt ctgttacaga taaatttatg gacttctctt 6750

 ttgaaaagac acacagtgca tatatgctgt tttacaaacg catggaacca 6800

 gaggaagaaa atggcagaga atacaaattt gatgtttcgt cagagttact 6850

 agagtggatt tggcatgata acatgcagtt tcttcaagac aaaaacattt 6900

 ttgaacatac atattttgga tttatgtggc aattgtgtag ttgtattccc 6950

 agtacattac cagatcctaa agctgtgtcc ttaatgacag caaagttaag 7000

 cacttccttt gtcctagaga catttattca ttctaaagaa aagcccacga 7050

 tgcttcagtg gattgaactg ttgacgaaac agtttaataa tagtcaggca 7100

 gcttgtgagt ggtttttaga tcgtatggct gatgacgact ggtggccaat 7150

 gcagatacta attaagtgcc ctaatcaaat tgtgagacag atgtttcagc 7200

 gtttgtgtat ccatgtgatt cagaggctga gacctgtgca tgctcatctc 7250

 tatttgcagc caggaatgga agatgggtca gatgatatgg atacctcagt 7300

 agaagatatt ggtggtcgtt catgtgtcac tcgctttgtg agaaccctgt 7350

 tattaattat ggaacatggt gtaaaacctc acagtaaaca tcttacagag 7400

 tattttgcct tcctttacga atttgcaaaa atgggtgaag aagagagcca 7450

 atttttgctt tcattgcaag ctatatctac aatggtacat ttttacatgg 7500

 gaacaaaagg acctgaaaat cctcaagttg aagtgttatc agaggaagaa 7550

 ggggaagaag aagaggagga agaagatatc ctctctctgg cagaagaaaa 7600

 atacaggcca gctgcccttg aaaagatgat agctttagtt gctcttttgg 7650

 ttgaacagtc tcgatcagaa aggcatttga cattatcaca gactgacatg 7700

 gcagcattaa caggaggaaa gggatttccc ttcttgtttc aacatattcg 7750

 tgatggcatc aatataagac aaacttgtaa tctgattttc agcctgtgtc 7800

 gatacaataa tcgacttgca gaacatattg tatctatgct tttcacatca 7850

 atagcaaagt tgactcctga ggcagccaat cctttcttta agttgttgac 7900

 tatgctaatg gagtttgctg gtggacctcc aggaatgcct ccctttgcat 7950

 cttatattct gcagaggata tgggaggtga ttgaatacaa tccttctcag 8000

 tgtctagatt ggttggcagt gcagacaccc cgaaataaac tggcacacag 8050

 ctgggtctta cagaatatgg aaaactgggt cgagcggttt cttttggctc 8100

 acaattatcc tagagtgagg acttctgcag cttatcttct ggtgtccctt 8150

 ataccaagca attcattccg tcagatgttc cggtcaacaa ggtctttgca 8200

 catcccaacc cgtgaccttc cactcagtcc agacacaaca gtagtcctac 8250

 atcaggtcta caacgtgctc cttggtttgc tctcaagagc caaactttat 8300

 gttgatgctg ctgttcatgg cactacaaag ctagtgccct attttagctt 8350

 tatgacttac tgtttaattt ccaaaactga gaagctgatg ttttccacat 8400

 atttcatgga tttgtggaac cttttccagc ctaaactttc tgagccagca 8450

 atagctacaa atcacaataa acaggctttg ctttcatttt ggtacaatgt 8500

 ctgtgctgac tgtccagaga atatccgcct tattgttcag aacccagtgg 8550

 taaccaagaa cattgccttc aattacatcc ttgctgacca tgatgatcag 8600

 gatgtggtgc tttttaaccg tgggatgctg ccagcgtact atggcattct 8650

 gaggctctgc tgtgagcagt ctcctgcatt cacacgacaa ctggcttctc 8700

 accagaacat ccagtgggcc tttaagaatc ttacaccaca tgccagccaa 8750

 taccctggag cagtagaaga actgtttaac ctgatgcagc tgtttatagc 8800

 tcagaggcca gatatgagag aagaagaatt agaagatatt aaacagttca 8850

 agaaaacaac cataagttgt tacttacgtt gcttagatgg ccgctcctgc 8900

 tggactactt taataagtgc cttcagaata ctattagaat ctgatgaaga 8950

 cagacttctt gttgtattta atcgaggatt gattctaatg acagagtctt 9000

 tcaacacttt gcacatgatg tatcacgaag ctacagcttg ccatgtgact 9050

 ggagatttag tagaacttct gtcaatattt ctttcggttt tgaagtctac 9100

 acgcccttat cttcagagaa aagatgtgaa acaagcatta atccagtggc 9150

 aggagcgaat tgaatttgcc cataaactgt taactcttct taattcctat 9200

 agtcctccag aacttagaaa tgcctgtata gatgtcctca aggaacttgt 9250

 acttttgagt ccccatgatt ttcttcatac tctggttccc tttctacaac 9300

 acaaccattg tacttaccat cacagtaata taccaatgtc tcttggacct 9350

 tatttccctt gtcgagaaaa tatcaagcta ataggaggga aaagcaatat 9400

 tcggcctccg cgccctgaac tcaatatgtg cctcttgccc acaatggtgg 9450

 aaaccagtaa gggcaaagat gacgtttatg atcgtatgct gctagactac 9500

 ttcttttctt atcatcagtt catccatcta ttatgccgag ttgcaatcaa 9550

 ctgtgaaaaa tttactgaaa cattagttaa gctgagtgtc ctagttgcct 9600

 atgaaggttt gccacttcat cttgcactgt tccccaaact ttggactgag 9650

 ctatgccaga ctcagtctgc tatgtcaaaa aactgcatca agcttttgtg 9700

 tgaagatcct gttttcgcag aatatattaa atgtatccta atggatgaaa 9750

 gaactttttt aaacaacaac attgtctaca cgttcatgac acatttcctt 9800

 ctaaaggttc aaagtcaagt gttttctgaa gcaaactgtg ccaatttgat 9850

 cagcactctt attacaaact tgataagcca gtatcagaac ctacagtctg 9900

 atttctccaa ccgagttgaa atttccaaag caagtgcttc tttaaatggg 9950

 gacctgaggg cactcgcttt gctcctgtca gtacacactc ccaaacagtt 10000

 aaacccagct ctaattccaa ctctgcaaga gcttttaagc aaatgcagga 10050

 cttgtctgca acagagaaac tcactccaag agcaagaagc caaagaaaga 10100

 aaaactaaag atgatgaagg agcaactccc attaaaaggc ggcgtgttag 10150

 cagtgatgag gagcacactg tagacagctg catcagtgac atgaaaacag 10200

 aaaccaggga ggtcctgacc ccaacgagca cttctgacaa tgagaccaga 10250

 gactcctcaa ttattgatcc aggaactgag caagatcttc cttcccctga 10300

 aaatagttct gttaaagaat accgaatgga agttccatct tcgttttcag 10350

 aagacatgtc aaatatcagg tcacagcatg cagaagaaca gtccaacaat 10400

 ggtagatatg acgattgtaa agaatttaaa gacctccact gttccaagga 10450

 ttctacccta gctgaggaag aatctgagtt cccttctact tctatctctg 10500

 cagttctgtc tgacttagct gacttgagaa gctgtgatgg ccaagctttg 10550

 ccctcccagg accctgaggt tgctttatct ctcagttgtg gccattccag 10600

 aggactcttt agtcatatgc agcaacatga cattttagat accctgtgta 10650

 ggaccattga atctacaatc catgtcgtca caaggatatc tggcaaagga 10700

 aaccaagctg cttcttgaca ttaggtgtag catgtctact tttaagtccc 10750

 tcacccccaa cccccatgct gtttgtataa gttttgctta tttgtttttg 10800

 tgcttcagtt tgtccagtgc tctctgcttg aatggcaaga tagatttata 10850

 ggcttaattc ttggtcaggc agaactccag atgaaaaaaa cttgcatctt 10900

 cagtatactt cctaaagggc aatcagataa tggatatgtt ttatgtaatt 10950

 aagagttcac tttagtggct ttcatttaat atggctgtct gggaagaaca 11000

 gggttgccta gccctgtaca atgtaattta aacttacagc atttttactg 11050

 tgtatgatat ggtgtcctct gtgccagttt tgtaccttat agaggcagat 11100

 tgcctccgat cgctgtggtt cttattatca aaattaagtt tacttgtata 11150

 cggaacaacc acaagaaatt tgattctgta aagaatcctc tttagctgtg 11200

 gcctggcagt atataaatgg tgctttattt aacagaatac ctgtggagga 11250

 aataaagcac acttgatgt 11269

<210> 2507
<211> 2000
<212> PRT
<213> Homo sapien

<400> 2507
 Leu Arg Arg Asn Leu Gln Arg Val Leu Ile Leu Leu Val Tyr Gly
   1               5                  10                  15

 Val Gln Met Arg Arg Lys Asn Ser Tyr Tyr Val Trp Gln Lys Ile
                  20                  25                  30

 Phe Gln Ile Gln Phe Pro Leu Tyr Thr Ala Tyr Lys His Asn Thr
                  35                  40                  45

 His Pro Thr Ile Glu Asp Ile Ser Thr Gln Glu Ser Asn Ile Leu
                  50                  55                  60

 Gly Ala Phe Cys Asp Met Asn Asp Val Glu Val Pro Leu His Leu
                  65                  70                  75

 Leu Arg Tyr Val Cys Leu Phe Cys Gly Lys Asn Gly Leu Ser Leu
                  80                  85                  90

 Met Lys Asp Cys Phe Glu Tyr Gly Thr Pro Glu Thr Leu Pro Phe
                  95                 100                 105

 Leu Ile Ala His Ala Phe Ile Thr Val Val Ser Asn Ile Arg Ile
                 110                 115                 120

 Trp Leu His Ile Pro Ala Val Met Gln His Ile Ile Pro Phe Arg
                 125                 130                 135

 Thr Tyr Val Ile Arg Tyr Leu Cys Lys Leu Ser Asp Gln Glu Leu
                 140                 145                 150

 Arg Gln Ser Ala Ala Arg Asn Met Ala Asp Leu Met Trp Ser Thr
                 155                 160                 165

 Val Lys Glu Pro Leu Asp Thr Thr Leu Cys Phe Asp Lys Glu Ser
                 170                 175                 180

 Leu Asp Leu Ala Phe Lys Tyr Phe Met Ser Pro Thr Leu Thr Met
                 185                 190                 195

 Arg Leu Ala Gly Leu Ser Gln Ile Thr Asn Gln Leu His Thr Phe
                 200                 205                 210

 Asn Asp Val Cys Asn Asn Glu Ser Leu Val Ser Asp Thr Glu Thr
                 215                 220                 225

 Ser Ile Ala Lys Glu Leu Ala Asp Trp Leu Ile Ser Asn Asn Val
                 230                 235                 240

 Val Glu His Ile Phe Gly Pro Asn Leu His Ile Glu Ile Ile Lys
                 245                 250                 255

 Gln Cys Gln Val Ile Leu Asn Phe Leu Ala Ala Glu Gly Arg Leu
                 260                 265                 270

 Ser Thr Gln His Ile Asp Cys Ile Trp Ala Ala Ala Gln Leu Lys
                 275                 280                 285

 His Cys Ser Arg Tyr Ile His Asp Leu Phe Pro Ser Leu Ile Lys
                 290                 295                 300

 Asn Leu Asp Pro Val Pro Leu Arg His Leu Leu Asn Leu Val Ser
                 305                 310                 315

 Ala Leu Glu Pro Ser Val His Thr Glu Gln Thr Leu Tyr Leu Ala
                 320                 325                 330

 Ser Met Leu Ile Lys Ala Leu Trp Asn Asn Ala Leu Ala Ala Lys
                 335                 340                 345

 Ala Gln Leu Ser Lys Gln Ser Ser Phe Ala Ser Leu Leu Asn Thr
                 350                 355                 360

 Asn Ile Pro Ile Gly Asn Lys Lys Glu Glu Glu Glu Leu Arg Arg
                 365                 370                 375

 Thr Ala Pro Ser Pro Trp Ser Pro Ala Ala Ser Pro Gln Ser Ser
                 380                 385                 390

 Asp Asn Ser Asp Thr His Gln Ser Gly Gly Ser Asp Ile Glu Met
                 395                 400                 405

 Asp Glu Gln Leu Ile Asn Arg Thr Lys His Val Gln Gln Arg Leu
                 410                 415                 420

 Ser Asp Thr Glu Glu Ser Met Gln Gly Ser Ser Asp Glu Thr Ala
                 425                 430                 435

 Asn Ser Gly Glu Asp Gly Ser Ser Gly Pro Gly Ser Ser Ser Gly
                 440                 445                 450

 His Ser Asp Gly Ser Ser Asn Glu Val Asn Ser Ser His Ala Ser
                 455                 460                 465

 Gln Ser Ala Gly Ser Pro Gly Ser Glu Val Gln Ser Glu Asp Ile
                 470                 475                 480

 Ala Asp Ile Glu Ala Leu Lys Glu Glu Asp Glu Asp Asp Asp His
                 485                 490                 495

 Gly His Asn Pro Pro Lys Ser Ser Cys Gly Thr Asp Leu Arg Asn
                 500                 505                 510

 Arg Lys Leu Glu Ser Gln Ala Gly Ile Cys Leu Gly Asp Ser Gln
                 515                 520                 525

 Gly Thr Ser Glu Arg Asn Gly Thr Ser Ser Gly Thr Gly Lys Asp
                 530                 535                 540

 Leu Val Phe Asn Thr Glu Ser Leu Pro Ser Val Asp Asn Arg Met
                 545                 550                 555

 Arg Met Leu Asp Ala Cys Ser His Ser Glu Asp Pro Glu His Asp
                 560                 565                 570

 Ile Ser Gly Glu Met Asn Ala Thr His Ile Ala Gln Gly Ser Gln
                 575                 580                 585

 Glu Ser Cys Ile Thr Arg Thr Gly Asp Phe Leu Gly Glu Thr Ile
                 590                 595                 600

 Gly Asn Glu Leu Phe Asn Cys Arg Gln Phe Ile Gly Pro Gln His
                 605                 610                 615

 His His His His His His His His His His His Asp Gly His Met
                 620                 625                 630

 Val Asp Asp Met Leu Ser Ala Asp Asp Val Ser Cys Ser Ser Ser
                 635                 640                 645

 Gln Val Ser Ala Lys Ser Glu Lys Asn Met Ala Asp Phe Asp Gly
                 650                 655                 660

 Glu Glu Ser Gly Cys Glu Glu Glu Leu Val Gln Ile Asn Ser His
                 665                 670                 675

 Ala Glu Leu Thr Ser His Leu Gln Gln His Leu Pro Asn Leu Ala
                 680                 685                 690

 Ser Ile Tyr His Glu His Leu Ser Gln Gly Pro Val Val His Lys
                 695                 700                 705

 His Gln Phe Asn Ser Asn Ala Val Thr Asp Ile Asn Leu Asp Asn
                 710                 715                 720

 Val Cys Lys Lys Gly Asn Thr Leu Leu Trp Asp Ile Val Gln Asp
                 725                 730                 735

 Glu Asp Ala Val Asn Leu Ser Glu Gly Leu Ile Asn Glu Ala Glu
                 740                 745                 750

 Lys Leu Leu Cys Ser Leu Val Cys Trp Phe Thr Asp Arg Gln Ile
                 755                 760                 765

 Arg Met Arg Phe Ile Glu Gly Cys Leu Glu Asn Leu Gly Asn Asn
                 770                 775                 780

 Arg Ser Val Val Ile Ser Leu Arg Leu Leu Pro Lys Leu Phe Gly
                 785                 790                 795

 Thr Phe Gln Gln Phe Gly Ser Ser Tyr Asp Thr His Trp Ile Thr
                 800                 805                 810

 Met Trp Ala Glu Lys Glu Leu Asn Met Met Lys Leu Phe Phe Asp
                 815                 820                 825

 Asn Leu Val Tyr Tyr Ile Gln Thr Val Arg Glu Gly Arg Gln Lys
                 830                 835                 840

 His Ala Leu Tyr Ser His Ser Ala Glu Val Gln Val Arg Leu Gln
                 845                 850                 855

 Phe Leu Thr Cys Val Phe Ser Thr Leu Gly Ser Pro Asp His Phe
                 860                 865                 870

 Arg Leu Ser Leu Glu Gln Val Asp Ile Leu Trp His Cys Leu Val
                 875                 880                 885

 Glu Asp Ser Glu Cys Tyr Asp Asp Ala Leu His Trp Phe Leu Asn
                 890                 895                 900

 Gln Val Arg Ser Lys Asp Gln His Ala Met Gly Met Glu Thr Tyr
                 905                 910                 915

 Lys His Leu Phe Leu Glu Lys Met Pro Gln Leu Lys Pro Glu Thr
                 920                 925                 930

 Ile Ser Met Thr Gly Leu Asn Leu Phe Gln His Leu Cys Asn Leu
                 935                 940                 945

 Ala Arg Leu Ala Thr Ser Ala Tyr Asp Gly Cys Ser Asn Ser Glu
                 950                 955                 960

 Leu Cys Gly Met Asp Gln Phe Trp Gly Ile Ala Leu Arg Ala Gln
                 965                 970                 975

 Ser Gly Asp Val Ser Arg Ala Ala Ile Gln Tyr Ile Asn Ser Tyr
                 980                 985                 990

 Tyr Ile Asn Gly Lys Thr Gly Leu Glu Lys Glu Gln Glu Phe Ile
                 995                1000                1005

 Ser Lys Cys Met Glu Ser Leu Met Ile Ala Ser Ser Ser Leu Glu
                1010                1015                1020

 Gln Glu Ser His Ser Ser Leu Met Val Ile Glu Arg Gly Leu Leu
                1025                1030                1035

 Met Leu Lys Thr His Leu Glu Ala Phe Arg Arg Arg Phe Ala Tyr
                1040                1045                1050

 His Leu Arg Gln Trp Gln Ile Glu Gly Thr Gly Ile Ser Ser His
                1055                1060                1065

 Leu Lys Ala Leu Ser Asp Lys Gln Ser Leu Pro Leu Arg Val Val
                1070                1075                1080

 Cys Gln Pro Ala Gly Leu Pro Asp Lys Met Thr Ile Glu Met Tyr
                1085                1090                1095

 Pro Ser Asp Gln Val Ala Asp Leu Arg Ala Glu Val Thr His Trp
                1100                1105                1110

 Tyr Glu Asn Leu Gln Lys Glu Gln Ile Asn Gln Gln Ala Gln Leu
                1115                1120                1125

 Gln Glu Phe Gly Gln Ser Asn Arg Lys Gly Glu Phe Pro Gly Gly
                1130                1135                1140

 Leu Met Gly Pro Val Arg Met Ile Ser Ser Gly His Glu Leu Thr
                1145                1150                1155

 Thr Asp Tyr Asp Glu Lys Ala Leu His Glu Leu Gly Phe Lys Asp
                1160                1165                1170

 Met Gln Met Val Phe Val Ser Leu Gly Ala Pro Arg Arg Glu Arg
                1175                1180                1185

 Lys Gly Glu Gly Val Gln Leu Pro Ala Ser Cys Leu Pro Pro Pro
                1190                1195                1200

 Gln Lys Asp Asn Ile Pro Met Leu Leu Leu Leu Gln Glu Pro His
                1205                1210                1215

 Leu Thr Thr Leu Phe Asp Leu Leu Glu Met Leu Ala Ser Phe Lys
                1220                1225                1230

 Pro Pro Ser Gly Lys Val Ala Val Asp Asp Ser Glu Ser Leu Arg
                1235                1240                1245

 Cys Glu Glu Leu His Leu His Ala Glu Asn Leu Ser Arg Arg Val
                1250                1255                1260

 Trp Glu Leu Leu Met Leu Leu Pro Thr Cys Pro Asn Met Leu Met
                1265                1270                1275

 Ala Phe Gln Asn Ile Ser Asp Glu Gln Ser Asn Asp Gly Phe Asn
                1280                1285                1290

 Trp Lys Glu Leu Leu Lys Ile Lys Ser Ala His Lys Leu Leu Tyr
                1295                1300                1305

 Ala Leu Glu Ile Ile Glu Ala Leu Gly Lys Pro Asn Arg Arg Ile
                1310                1315                1320

 Arg Arg Glu Ser Thr Gly Ser Tyr Ser Asp Leu Tyr Pro Asp Ser
                1325                1330                1335

 Asp Asp Ser Ser Glu Asp Gln Val Glu Asn Ser Lys Asn Ser Trp
                1340                1345                1350

 Ser Cys Lys Phe Val Ala Ala Gly Gly Leu Gln Gln Leu Leu Glu
                1355                1360                1365

 Ile Phe Asn Ser Gly Ile Leu Glu Pro Lys Glu Gln Glu Ser Trp
                1370                1375                1380

 Thr Val Trp Gln Leu Asp Cys Leu Ala Cys Leu Leu Lys Leu Ile
                1385                1390                1395

 Cys Gln Phe Ala Val Asp Pro Ser Asp Leu Asp Leu Ala Tyr His
                1400                1405                1410

 Asp Val Phe Ala Trp Ser Gly Ile Ala Glu Ser His Arg Lys Arg
                1415                1420                1425

 Thr Trp Pro Gly Lys Ser Arg Lys Ala Ala Gly Asp His Ala Lys
                1430                1435                1440

 Gly Leu His Ile Pro Arg Leu Thr Glu Val Phe Leu Val Leu Val
                1445                1450                1455

 Gln Gly Thr Ser Leu Ile Gln Arg Leu Met Ser Val Ala Tyr Thr
                1460                1465                1470

 Tyr Asp Asn Leu Ala Pro Arg Val Leu Lys Ala Gln Ser Asp His
                1475                1480                1485

 Arg Ser Arg His Glu Val Ser His Tyr Ser Met Trp Leu Leu Val
                1490                1495                1500

 Ser Trp Ala His Cys Cys Ser Leu Val Lys Ser Ser Leu Ala Asp
                1505                1510                1515

 Ser Asp His Leu Gln Asp Trp Leu Lys Lys Leu Thr Leu Leu Ile
                1520                1525                1530

 Pro Glu Thr Ala Val Arg His Glu Ser Cys Ser Gly Leu Tyr Lys
                1535                1540                1545

 Leu Ser Leu Ser Gly Leu Asp Gly Gly Asp Ser Ile Asn Arg Ser
                1550                1555                1560

 Phe Leu Leu Leu Ala Ala Ser Thr Leu Leu Lys Phe Leu Pro Asp
                1565                1570                1575

 Ala Gln Ala Leu Lys Pro Ile Arg Ile Asp Asp Tyr Glu Glu Glu
                1580                1585                1590

 Pro Ile Leu Lys Pro Gly Cys Lys Glu Tyr Phe Trp Leu Leu Cys
                1595                1600                1605

 Lys Leu Val Asp Asn Ile His Ile Lys Asp Ala Ser Gln Thr Thr
                1610                1615                1620

 Leu Leu Asp Leu Asp Ala Leu Ala Arg His Leu Ala Asp Cys Ile
                1625                1630                1635

 Arg Ser Arg Glu Ile Leu Asp His Gln Asp Gly Asn Val Glu Asp
                1640                1645                1650

 Asp Gly Leu Thr Gly Leu Leu Arg Leu Ala Thr Ser Val Val Lys
                1655                1660                1665

 His Lys Pro Pro Phe Lys Phe Ser Arg Glu Gly Gln Glu Phe Leu
                1670                1675                1680

 Arg Asp Ile Phe Asn Leu Leu Phe Leu Leu Pro Ser Leu Lys Asp
                1685                1690                1695

 Arg Gln Gln Pro Lys Cys Lys Ser His Ser Ser Arg Ala Ala Ala
                1700                1705                1710

 Tyr Asp Leu Leu Val Glu Met Val Lys Gly Ser Val Glu Asn Tyr
                1715                1720                1725

 Arg Leu Ile His Asn Trp Val Met Ala Gln His Met Gln Ser His
                1730                1735                1740

 Ala Pro Tyr Lys Trp Asp Tyr Trp Pro His Glu Asp Val Arg Ala
                1745                1750                1755

 Glu Cys Arg Phe Val Gly Leu Thr Asn Leu Gly Ala Thr Cys Tyr
                1760                1765                1770

 Leu Ala Ser Thr Ile Gln Gln Leu Tyr Met Ile Pro Glu Ala Arg
                1775                1780                1785

 Gln Ala Val Phe Thr Ala Lys Tyr Ser Glu Asp Met Lys His Lys
                1790                1795                1800

 Thr Thr Leu Leu Glu Leu Gln Lys Met Phe Thr Tyr Leu Met Glu
                1805                1810                1815

 Ser Glu Cys Lys Ala Tyr Asn Pro Arg Pro Phe Cys Lys Thr Tyr
                1820                1825                1830

 Thr Met Asp Lys Gln Pro Leu Asn Thr Gly Glu Gln Lys Asp Met
                1835                1840                1845

 Thr Glu Phe Phe Thr Asp Leu Ile Thr Lys Ile Glu Glu Met Ser
                1850                1855                1860

 Pro Glu Leu Lys Asn Thr Val Lys Ser Leu Phe Gly Gly Val Ile
                1865                1870                1875

 Thr Asn Asn Val Val Ser Leu Asp Cys Glu His Val Ser Gln Thr
                1880                1885                1890

 Ala Glu Glu Phe Tyr Thr Val Arg Cys Gln Val Ala Asp Met Lys
                1895                1900                1905

 Asn Ile Tyr Glu Ser Leu Asp Glu Val Thr Ile Lys Asp Thr Leu
                1910                1915                1920

 Glu Gly Asp Asn Met Tyr Thr Cys Ser His Cys Gly Lys Lys Val
                1925                1930                1935

 Arg Ala Glu Lys Arg Ala Cys Phe Lys Lys Leu Pro Arg Ile Leu
                1940                1945                1950

 Ser Phe Asn Thr Met Arg Tyr Thr Phe Asn Met Val Thr Met Met
                1955                1960                1965

 Lys Glu Lys Val Asn Thr His Phe Ser Phe Pro Leu Arg Leu Asp
                1970                1975                1980

 Met Thr Pro Tyr Thr Glu Asp Phe Leu Met Gly Lys Ser Glu Arg
                1985                1990                1995

 Lys Glu Gly Phe Lys
                2000

<210> 2508
<211> 3455
<212> DNA
<213> Homo sapien

<400> 2508
 atgttgttgt ctcccaaatt ctccttatcc accattcaca tacgactgac 50

 ggccaaagga ttgcttcgaa accttcgact tccttcaggg tttaggagaa 100

 gcactgttgt tttccacaca gttgaaaaga gcaggcaaaa gaatcctcga 150

 agcttatgta tccagccaca gacagctccc gatgcgctgc cccctgagaa 200

 aacacttgaa ttgacgcaat ataaaacaaa atgtgaaaac caaagtggat 250

 ttatcctgca gctcaagcag cttcttgcct gtggtaatac caagtttgag 300

 gcattgacag ttgtgattca gcacctgctg tctgagcggg aggaagcact 350

 gaaacaacac aaaaccctat ctcaagaact tgttaacctc cggggagagc 400

 tagtcactgc ttcaaccacc tgtgagaaat tagaaaaagc caggaatgag 450

 ttacaaacag tgtatgaagc attcgtccag cagcaccagg ctgaaaaaac 500

 agaacgagag aatcggctta aagagtttta caccagggag tatgaaaagc 550

 ttcgggacac ttacattgaa gaagcagaga agtacaaaat gcaattgcaa 600

 gagcagtttg acaacttaaa tgctgcgcat gaaacctcta agttggaaat 650

 tgaagctagc cactcagaga aacttgaatt gctaaagaag gcctatgaag 700

 cctccctttc agaaattaag aaaggccatg aaatagaaaa gaaatcgctt 750

 gaagatttac tttctgagaa gcaggaatcg ctagagaagc aaatcaatga 800

 tctgaagagt gaaaatgatg ctttaaatga aaaattgaaa tcagaagaac 850

 aaaaaagaag agcaagagaa aaagcaaatt tgaaaaatcc tcagatcatg 900

 tatctagaac aggagttaga aagcctgaaa gctgtgttag agatcaagaa 950

 tgagaaactg catcaacagg acatcaagtt aatgaaaatg gagaaactgg 1000

 tggacaacaa cacagcattg gttgacaaat tgaagcgttt ccagcaggag 1050

 aatgaagaat tgaaagctcg gatggacaag cacatggcaa tctcaaggca 1100

 gctttccacg gagcaggctg ttctgcaaga gtcgctggag aaggagtcga 1150

 aagtcaacaa gcgactctct atggaaaacg aggagcttct gtggaaactg 1200

 cacaatgggg acctgtgtag ccccaagaga tcccccacat cctccgccat 1250

 ccctttgcag tcaccaagga attcgggctc cttccctagc cccagcattt 1300

 cacccagatg acacgtcccc aaagtccaca gactctctga aagcattttg 1350

 atgcaggtct gcaggactga ccccaaggag gaacgtgggc acaagaggta 1400

 tatcagcaca cgtgtgatca ccgtagggta actggagcgt caccaccggc 1450

 ggaatcgcag cttctgagac tggaagtctg gaggaagact tttgcctccg 1500

 tccaaaagat tcctccaaaa aaagatttaa aaaaagattt cggcatcgac 1550

 acggacgttg ttgcacaaag cacttaaaga acgagagcat cttgttcatt 1600

 gcctttttca cctaagcata aggggaaaaa ctctcagggc cctattaaga 1650

 tttataacct ttgtaatgtt cttcaccaca gacaccttct tgtgagtttt 1700

 cagtctgact gtgggggtgg ggggtgtgaa tgaaatggat gtcacagagt 1750

 gtcatgtgtc tgatgcagcc tcctctgctg tgtattaaat gtcaaaatct 1800

 gaatatatct ggatatgtac taatcaaata ataatcaatc aatcagcata 1850

 tacatttcag ccaaagccat agaagaaaaa gcaatagttg cttgaattat 1900

 gatcatctac caccaactct gctcagccct gtaacagggt agggagaggg 1950

 tataacagga agagctttga cttgtccctg tctatacatt ctctgtatct 2000

 tttgggggta acttcttggc agtttttcag tgttcagcca tgtcagttga 2050

 aactagattt ttctgtagat tttttactta cccatgtgag cctaacacta 2100

 tcctgtaatt cattttctca ggctatgtgt aaatgtagaa ccctaatttt 2150

 tctataaaaa aacaaactaa ctaactgtgt aaagaaagaa aaagggaagt 2200

 accaatgggt ttttccacct tatttttacc tttgatctac ccttgcagat 2250

 ttaacctgtc ttcttccctc ccattattct cattttcctt ttacctttct 2300

 ccaccatcca gagccacaaa agcaaacctt ctacctccta cctacttttc 2350

 tctgggacaa ggataaagga atatgatttt ccagagcccc agagccagct 2400

 catcttccag gtgctgaaac cactttccaa ataaactaaa gcctggattt 2450

 gatattacaa attttgggaa atcttagaat aaagaacgag aacaaggaag 2500

 tcattggcta gtataattaa gaaaggtagg attcagtgct taccgatgat 2550

 gcagtacttg atagaagaaa acagtctggg aggatagcgc tcatttttca 2600

 gttacccttt aaggagtccc tttgtctttg ggaaagtagc agaatggtcc 2650

 gcttctttcc catgagtgga aaatgtggct tgtccaactc tcctccaggt 2700

 tgcatttcag tttctttcca aaacttatta cctcccctaa tcctgagact 2750

 ttggaaaagg tggaaggaag aactgttgct ttatctcccc ctccctgcat 2800

 gtgtcaacat tgtgatgtca gtatttacta atctacattc agtggctgta 2850

 caaataacag ctgtagtaag aagagattca ggatgctaga ggtgaatatt 2900

 tgggtcattt acatgtacac tacatagcaa gttgatactc atgttgcatg 2950

 ttcttttaaa ttagtgattt tgtgtcttaa gtctttaact tccaatactt 3000

 catcatgtat gtaaccttcc atgtttgctt ctgataaatg gaaatgtagg 3050

 ttcactgcca cttcatgaga tatctctgct cacgcttcca agttgttctc 3100

 aatgacatta gccaaagttg ggtttgccat tcatccccta ggcatggtaa 3150

 atcttgtgtt gttccctgct gtcctccgta ttacgtgacc ggcaaataaa 3200

 tctcatagca gttaatataa aacatctttg gaggatggga gagaacagga 3250

 gggaagatgg gaaacaaaat agagaattct taagattttg tttaaaccaa 3300

 atgtttcatg tagaatgcaa aatgttggca cgtcaaaaat atgaatgtgt 3350

 agacaactgt agttgtgctc agtttgtagt gatgggaagt gtattttact 3400

 ctgatcaaat aaataatgct ggaatactca agaattgcaa aaaaaaaaaa 3450

 aaaaa 3455

<210> 2509
<211> 436
<212> PRT
<213> Homo sapien

<400> 2509
 Met Leu Leu Ser Pro Lys Phe Ser Leu Ser Thr Ile His Ile Arg
   1               5                  10                  15

 Leu Thr Ala Lys Gly Leu Leu Arg Asn Leu Arg Leu Pro Ser Gly
                  20                  25                  30

 Phe Arg Arg Ser Thr Val Val Phe His Thr Val Glu Lys Ser Arg
                  35                  40                  45

 Gln Lys Asn Pro Arg Ser Leu Cys Ile Gln Pro Gln Thr Ala Pro
                  50                  55                  60

 Asp Ala Leu Pro Pro Glu Lys Thr Leu Glu Leu Thr Gln Tyr Lys
                  65                  70                  75

 Thr Lys Cys Glu Asn Gln Ser Gly Phe Ile Leu Gln Leu Lys Gln
                  80                  85                  90

 Leu Leu Ala Cys Gly Asn Thr Lys Phe Glu Ala Leu Thr Val Val
                  95                 100                 105

 Ile Gln His Leu Leu Ser Glu Arg Glu Glu Ala Leu Lys Gln His
                 110                 115                 120

 Lys Thr Leu Ser Gln Glu Leu Val Asn Leu Arg Gly Glu Leu Val
                 125                 130                 135

 Thr Ala Ser Thr Thr Cys Glu Lys Leu Glu Lys Ala Arg Asn Glu
                 140                 145                 150

 Leu Gln Thr Val Tyr Glu Ala Phe Val Gln Gln His Gln Ala Glu
                 155                 160                 165

 Lys Thr Glu Arg Glu Asn Arg Leu Lys Glu Phe Tyr Thr Arg Glu
                 170                 175                 180

 Tyr Glu Lys Leu Arg Asp Thr Tyr Ile Glu Glu Ala Glu Lys Tyr
                 185                 190                 195

 Lys Met Gln Leu Gln Glu Gln Phe Asp Asn Leu Asn Ala Ala His
                 200                 205                 210

 Glu Thr Ser Lys Leu Glu Ile Glu Ala Ser His Ser Glu Lys Leu
                 215                 220                 225

 Glu Leu Leu Lys Lys Ala Tyr Glu Ala Ser Leu Ser Glu Ile Lys
                 230                 235                 240

 Lys Gly His Glu Ile Glu Lys Lys Ser Leu Glu Asp Leu Leu Ser
                 245                 250                 255

 Glu Lys Gln Glu Ser Leu Glu Lys Gln Ile Asn Asp Leu Lys Ser
                 260                 265                 270

 Glu Asn Asp Ala Leu Asn Glu Lys Leu Lys Ser Glu Glu Gln Lys
                 275                 280                 285

 Arg Arg Ala Arg Glu Lys Ala Asn Leu Lys Asn Pro Gln Ile Met
                 290                 295                 300

 Tyr Leu Glu Gln Glu Leu Glu Ser Leu Lys Ala Val Leu Glu Ile
                 305                 310                 315

 Lys Asn Glu Lys Leu His Gln Gln Asp Ile Lys Leu Met Lys Met
                 320                 325                 330

 Glu Lys Leu Val Asp Asn Asn Thr Ala Leu Val Asp Lys Leu Lys
                 335                 340                 345

 Arg Phe Gln Gln Glu Asn Glu Glu Leu Lys Ala Arg Met Asp Lys
                 350                 355                 360

 His Met Ala Ile Ser Arg Gln Leu Ser Thr Glu Gln Ala Val Leu
                 365                 370                 375

 Gln Glu Ser Leu Glu Lys Glu Ser Lys Val Asn Lys Arg Leu Ser
                 380                 385                 390

 Met Glu Asn Glu Glu Leu Leu Trp Lys Leu His Asn Gly Asp Leu
                 395                 400                 405

 Cys Ser Pro Lys Arg Ser Pro Thr Ser Ser Ala Ile Pro Leu Gln
                 410                 415                 420

 Ser Pro Arg Asn Ser Gly Ser Phe Pro Ser Pro Ser Ile Ser Pro
                 425                 430                 435

 Arg


<210> 2510
<211> 2704
<212> DNA
<213> Homo sapien

<400> 2510
 gggagaaacg ttctcactcg ctctctgctc gctgcgggcg ctccccgccc 50

 tctgctgcca gaaccttggg gatgtgccta gacccggcgc agcacacgtc 100

 cgggccaacc gcgagcagaa caaacctttg gcgggcggcc aggaggctcc 150

 ctcccagcca ccgcccccct ccagcgcctt tttttccccc catacaatac 200

 aagatcttcc ttcctcagtt cccttaaagc acagcccagg gaaacctcct 250

 cacagttttc atccagccac gggccagcat gtctgggggc aaatacgtag 300

 actcggaggg acatctctac accgttccca tccgggaaca gggcaacatc 350

 tacaagccca acaacaaggc catggcagac gagctgagcg agaagcaagt 400

 gtacgacgcg cacaccaagg agatcgacct ggtcaaccgc gaccctaaac 450

 acctcaacga tgacgtggtc aagattgact ttgaagatgt gattgcagaa 500

 ccagaaggga cacacagttt tgacggcatt tggaaggcca gcttcaccac 550

 cttcactgtg acgaaatact ggttttaccg cttgctgtct gccctctttg 600

 gcatcccgat ggcactcatc tggggcattt acttcgccat tctctctttc 650

 ctgcacatct gggcagttgt accatgcatt aagagcttcc tgattgagat 700

 tcagtgcatc agccgtgtct attccatcta cgtccacacc gtctgtgacc 750

 cactctttga agctgttggg aaaatattca gcaatgtccg catcaacttg 800

 cagaaagaaa tataaatgac atttcaagga tagaagtata cctgattttt 850

 tttcctttta attttcctgg tgccaatttc aagttccaag ttgctaatac 900

 agcaacaatt tatgaattga attatcttgg ttgaaaataa aaagatcact 950

 ttctcagttt tcataagtat tatgtctctt ctgagctatt tcatctattt 1000

 ttggcagtct gaatttttaa aacccattta aatttttttc cttacctttt 1050

 tatttgcatg tggatcaacc atcgctttat tggctgagat atgaacatat 1100

 tgttgaaagg taatttgaga gaaatatgaa gaactgagga ggaaaaaaaa 1150

 aaaaaagaaa agaaccaaca acctcaactg cctactccaa aatgttggtc 1200

 attttatgtt aagggaagaa ttccagggta tggccatgga gtgtacaagt 1250

 atgtgggcag attttcagca aactcttttc ccactgttta aggagttagt 1300

 ggattactgc cattcacttc ataatccagt aggatccagt gatccttaca 1350

 agttagaaaa cataatcttc tgccttctca tgatccaact aatgccttac 1400

 tcttcttgaa attttaacct atgatatttt ctgtgcctga atatttgtta 1450

 tgtagataac aagacctcag tgccttcctg tttttcacat tttccttttc 1500

 aaatagggtc taactcagca actcgcttta ggtcagcagc ctccctgaag 1550

 accaaaatta gaatatccat gacctagttt tccatgcgtg tttctgactc 1600

 tgagctacag agtctggtga agctcacttc tgggcttcat ctggcaacat 1650

 ctttatccgt agtgggtatg gttgacacta gcccaatgaa atgaattaaa 1700

 gtggaccaat agggctgagc tctctgtggg ctggcagtcc tggaagccag 1750

 ctttccctgc ctctcatcaa ctgaatgagg tcagcatgtc tattcagctt 1800

 cgtttatttt caagaataat cacgctttcc tgaatccaaa ctaatccatc 1850

 accggggtgg tttagtggct caacattgtg ttcccatttc agctgatcag 1900

 tgggcctcca aggaggggct gtaaaatgga ggccattgtg tgagcctatc 1950

 agagttgctg caaacctgac ccctgctcag taaagcactt gcaaccgtct 2000

 gttatgctgt gacacatggc ccctccccct gccaggagct ttggacctaa 2050

 tccaagcatc cctttgccca gaaagaagat gggggaggag gcagtaataa 2100

 aaagattgaa gtattttgct ggaataagtt caaattcttc tgaactcaaa 2150

 ctgaggaatt tcacctgtaa acctgagtcg tacagaaagc tgcctggtat 2200

 atccaaaagc tttttattcc tcctgctcat attgtgattc tgcctttggg 2250

 gacttttctt aaaccttcag ttatgatttt tttttcatac acttattgga 2300

 actctgcttg atttttgcct cttccagtct tcctgacact ttaattacca 2350

 acctgttacc tactttgact ttttgcattt aaaacagaca ctggcatgga 2400

 tatagtttta cttttaaact gtgtacataa ctgaaaatgt gctatactgc 2450

 atacttttta aatgtaaaga tatttttatc tttatatgaa gaaaatcact 2500

 taggaaatgg ctttgtgatt caatctgtaa actgtgtatt ccaagacatg 2550

 tctgttctac atagatgctt agtccctcat gcaaatcaat tactggtcca 2600

 aaagattgct gaaattttat atgcttactg atatatttta caatttttta 2650

 tcatgcatgt cctgtaaagg ttacaagcct gcacaataaa aatgtttaac 2700

 ggtt 2704

<210> 2511
<211> 178
<212> PRT
<213> Homo sapien

<400> 2511
 Met Ser Gly Gly Lys Tyr Val Asp Ser Glu Gly His Leu Tyr Thr
   1               5                  10                  15

 Val Pro Ile Arg Glu Gln Gly Asn Ile Tyr Lys Pro Asn Asn Lys
                  20                  25                  30

 Ala Met Ala Asp Glu Leu Ser Glu Lys Gln Val Tyr Asp Ala His
                  35                  40                  45

 Thr Lys Glu Ile Asp Leu Val Asn Arg Asp Pro Lys His Leu Asn
                  50                  55                  60

 Asp Asp Val Val Lys Ile Asp Phe Glu Asp Val Ile Ala Glu Pro
                  65                  70                  75

 Glu Gly Thr His Ser Phe Asp Gly Ile Trp Lys Ala Ser Phe Thr
                  80                  85                  90

 Thr Phe Thr Val Thr Lys Tyr Trp Phe Tyr Arg Leu Leu Ser Ala
                  95                 100                 105

 Leu Phe Gly Ile Pro Met Ala Leu Ile Trp Gly Ile Tyr Phe Ala
                 110                 115                 120

 Ile Leu Ser Phe Leu His Ile Trp Ala Val Val Pro Cys Ile Lys
                 125                 130                 135

 Ser Phe Leu Ile Glu Ile Gln Cys Ile Ser Arg Val Tyr Ser Ile
                 140                 145                 150

 Tyr Val His Thr Val Cys Asp Pro Leu Phe Glu Ala Val Gly Lys
                 155                 160                 165

 Ile Phe Ser Asn Val Arg Ile Asn Leu Gln Lys Glu Ile
                 170                 175

<210> 2512
<211> 1835
<212> DNA
<213> Homo sapien

<400> 2512
 atccatccct gtggagctgc agagcatctt catgtgagta gacggatgga 50

 cataaataga ttcatgctca tttaggaagc tgggagtttc gtgaagctga 100

 gggtgagttc ctgtgattct tgttcgcttc aacaaaaagt gggagaccaa 150

 gtttttatag caaaagacca aattagctgt agagtcttga atgcagaaaa 200

 aaattaccct agctttctta gcacttaggg ttttgtgagg attcagtgtt 250

 tagcacagtg cttggcacat agtaagccct agtaaatgtt aaatattgtt 300

 attagtgttt cgtaaaactt gagaaataga gctgagctca ttcccttcct 350

 gttgattcaa aaataatacc tacatgaaaa catgattcca agttgattga 400

 atgttgtagg aattactggt ttagagtagc ccagttctcg gcctaccctg 450

 ctggttggga tcttactgta ttcttgaatg cactggtttg aaaatatgcc 500

 agacttcagc ccccaaggaa acaaggctgc aagaatttat gaactccagc 550

 tggaaaaggt aaaggtgacc tttggctagc cacatactgg accttacccc 600

 actgacgtct ttcagaacat tccaagggtt ttcctcaagg aacatttttg 650

 agctagaaat taaaatgggt tctctggcag actgcacccc ttgagtcaaa 700

 gttaacagta ttcctttgaa tgcaataata gaggcttttc tgcgttaagg 750

 gagaaggaat gaccaattga acttacacat tccccaggca ggtccctttg 800

 ccggccccta caggctgggg tggcccctcc tgtcctcagg gatcagactc 850

 ccagactggt tagttctgca tgtttccatc aaattaaagg ttattccctg 900

 gccgcctcct ggagaaaacc aaccccaccc tgccagctgg gggcaatggg 950

 gcagggattt tggcctctca gaacagctcc tagaggctgc tcatgactga 1000

 atgttttccc aaatcaccta aatatcggtt tgctttttgt tttgggggag 1050

 aggatttagc ctcttacttc cctgatggat tcaaagtttt atctatctcc 1100

 ttatctcctg ccctgtcttg gcacaactct ggatagattg caggtgtgga 1150

 atttgctgga gtttggtgac ttcgtcaaat tcctttggat tctgttccgc 1200

 caaatcagca gtctcgtcct gtggatgcag tgactggaat ttcccatctg 1250

 caaagcatct ctgtagccca gattttgtgg agccttaaga cactccctca 1300

 atgccaccct gaccccacgg ctggagaacc ctgtgcttat gtggtgggca 1350

 gggccactgt tgatggagga tggcggggac ggggtggtgc tcaaaggatc 1400

 tgtggtgctg gaggtctaca cgcctctcag gacagcgtgt caggaacctc 1450

 agagcagctt cacatctgcc aaagctgaga gggagcgaac ttgggaagca 1500

 ttttgctcat tgtcctaccc aagtattaat agcataatag ttgatgccaa 1550

 aggagatggt gacgtccctt ccactgtagt tgctgtcaca accttgacgt 1600

 ctttaagcta atggccgttt gcatctgtgt cttcaaacag atcctggtta 1650

 cagccatttt gtgtgattca cttcgggggt taagtaatgc aggattctgc 1700

 aaacaaggtg tcgccgtcca aatgtactgt cctggcatag agagcactgc 1750

 tttgttttcc actgttgtag agaaaactag ggagaacttt atttttcaat 1800

 aaacttttct tgtgtgaaaa aaaaaaaaaa aaaaa 1835

<210> 2513
<211> 63
<212> PRT
<213> Homo sapien

<400> 2513
 Met Ala Val Cys Ile Cys Val Phe Lys Gln Ile Leu Val Thr Ala
   1               5                  10                  15

 Ile Leu Cys Asp Ser Leu Arg Gly Leu Ser Asn Ala Gly Phe Cys
                  20                  25                  30

 Lys Gln Gly Val Ala Val Gln Met Tyr Cys Pro Gly Ile Glu Ser
                  35                  40                  45

 Thr Ala Leu Phe Ser Thr Val Val Glu Lys Thr Arg Glu Asn Phe
                  50                  55                  60

 Ile Phe Gln


<210> 2514
<211> 1602
<212> DNA
<213> Homo sapien

<400> 2514
 ctcctacccg gacaccgacg tcattctcat gtgcttctcg gtggacagcc 50

 cggactcgct ggagaacatc cccgagaagt gggtccccga ggtgaagcac 100

 ttctgtccca atgtgcccat catcctggtg gccaacaaaa aagacctgcg 150

 cagcgacgag catgtccgca cagagctggc ccgcatgaag caggaacccc 200

 accggcctgc ctggcatctg tctgctgacg cctctggctt gcgccaggac 250

 ttggcgtggg caccgggcgc ccccatccca gtgtctgtgt gcgtccagct 300

 gtgttgcaca ggcctgggct ccccactgag tgccaagggt cccctgagca 350

 tgcttttctg aagagccggg cctcagagtg tgtggctgtg tgtctgttcg 400

 actctcctcg ccccattttc accccacccc cgcctctgat ccccgggggc 450

 gagattggcg cgggagtgtg gccgcgcccc atcagatgtt ctcccttcac 500

 cagcgggagc ttgatatccc ttgtctgtaa catagacccc gggtactgcg 550

 ggaggggagg gctgctgggg aggatggggg gatgttatat aaatatagat 600

 ataattttat tttcggagct aagatggtgt tatttaaggg tggtgatggg 650

 tgagcgctct ggcccaggct gggccagact cccgcccaag catgaacagg 700

 acttgaccat ctttccaacc cctggggaag acatttgcaa ctgacttggg 750

 gaggacacag cttcagcaca gcctctcctg cgggccagcc cgctgcgaac 800

 cctccaccag ctaccggagg gaggagggag gatgcgctgt ggggttgttt 850

 ttgccataag cgaactttgt gcctgtccta gaagtgaaaa ttgttcagtc 900

 caagaaactg atgttatttg atttatttaa aggctaaaat ttgttttttt 950

 attctttgca caattgtttc attgtttgac acttaatgca ctcgtcattt 1000

 gcatacgaca gtagcattct gaccacactt gtacgctgta acctcatcta 1050

 cttctgatgt ttttaaaaaa tgacttttaa caaggagagg gaaaagaaac 1100

 ccactaaatt ttgctttgtt tccttgaaga atgtggcaac actgttttgt 1150

 gattttattt gtgcaggtca tgcacacagt tttgataaag ggcagtaaca 1200

 agtattgggg cctatttttt ttttttttcc acaaggcatt ctctaaagct 1250

 atgtgaaatt ttctctgcac ctctgtacag agaatacacc tgcccctgta 1300

 tatccttttt tcccctcccc tccctcccag tggtacttct actaaattgt 1350

 tgtcttgttt tttatttttt aaataaactg acaaatgaca aaatggtgag 1400

 cttatgatgt ttacataaaa gttctataag ctgtgtatac agttttttat 1450

 gtaaaatatt aaaagactat gatgatgaca tttaaaaaaa aattcctctc 1500

 cacttctcat tatcttctat ttcttaaact atatcttacc tttacaaccc 1550

 ttctcattct cctattctct acctccctct tcctcaaacc ctttttatta 1600

 ca 1602

<210> 2515
<211> 119
<212> PRT
<213> Homo sapien

<400> 2515
 Ser Tyr Pro Asp Thr Asp Val Ile Leu Met Cys Phe Ser Val Asp
   1               5                  10                  15

 Ser Pro Asp Ser Leu Glu Asn Ile Pro Glu Lys Trp Val Pro Glu
                  20                  25                  30

 Val Lys His Phe Cys Pro Asn Val Pro Ile Ile Leu Val Ala Asn
                  35                  40                  45

 Lys Lys Asp Leu Arg Ser Asp Glu His Val Arg Thr Glu Leu Ala
                  50                  55                  60

 Arg Met Lys Gln Glu Pro His Arg Pro Ala Trp His Leu Ser Ala
                  65                  70                  75

 Asp Ala Ser Gly Leu Arg Gln Asp Leu Ala Trp Ala Pro Gly Ala
                  80                  85                  90

 Pro Ile Pro Val Ser Val Cys Val Gln Leu Cys Cys Thr Gly Leu
                  95                 100                 105

 Gly Ser Pro Leu Ser Ala Lys Gly Pro Leu Ser Met Leu Phe
                 110                 115

<210> 2516
<211> 4573
<212> DNA
<213> Homo sapien

<400> 2516
 cgcgtgtcta cgcggacgca ccggctaagc tgcttctgcc gccgccggcc 50

 gcctgggacc ttgcggtgag gctgcgcggg gccgaggccg cctccgagcg 100

 ccaggtttat tcagtcacca tgaagctgct gctgctgcac ccggccttcc 150

 agagctgcct cctgctgacc ctgcttggct tatggagaac cacccctgag 200

 gctcacgctt catccctggg tgcaccagct atcagcgctg cctccttcct 250

 gcaggatcta atacatcggt atggcgaggg tgacagcctc actctgcagc 300

 agctgaaggc cctgctcaac cacctggatg tgggagtggg ccggggtaat 350

 gtcacccagc acgtgcaagg acacaggaac ctctccacgt gctttagttc 400

 tggagacctc ttcactgccc acaatttcag cgagcagtcg cggattggga 450

 gcagcgagct ccaggagttc tgccccacca tcctccagca gctggattcc 500

 cgggcctgca cctcggagaa ccaggaaaac gaggagaatg agcagacgga 550

 ggaggggcgg ccaagcgctg ttgaagtgtg gggatacggt ctcctctgtg 600

 tgaccgtcat ctccctctgc tccctcctgg gggccagcgt ggtgcccttc 650

 atgaagaaga ccttttacaa gaggctgctg ctctacttca tagctctggc 700

 gattggaacc ctctactcca acgccctctt ccagctcatc ccggaggcat 750

 ttggtttcaa ccctctggaa gattattatg tctccaagtc tgcagtggtg 800

 tttgggggct tttatctttt ctttttcaca gagaagatct tgaagattct 850

 tcttaagcag aaaaatgagc atcatcatgg acacagccat tatgcctctg 900

 agtcgcttcc ctccaagaag gaccaggagg agggggtgat ggagaagctg 950

 cagaacgggg acctggacca catgattcct cagcactgca gcagtgagct 1000

 ggacggcaag gcgcccatgg tggacgagaa ggtcattgtg ggctcgctct 1050

 ctgtgcagga cctgcaggct tcccagagtg cttgctactg gctgaaaggt 1100

 gtccgctact ctgatatcgg cactctggcc tggatgatca ctctgagcga 1150

 cggcctccac aatttcatcg atggcctggc catcggtgct tccttcactg 1200

 tgtcagtttt ccaaggcatc agcacctcgg tggccatcct ctgtgaggag 1250

 ttcccacatg agctaggaga ctttgtcatc ctgctcaacg ctgggatgag 1300

 catccaacaa gctctcttct tcaacttcct ttctgcctgc tgctgctacc 1350

 tgggtctggc ctttggcatc ctggccggca gccacttctc tgccaactgg 1400

 atttttgcgc tagctggagg aatgttcttg tatatttctc tggctgatat 1450

 gttccctgag atgaatgagg tctgtcaaga ggatgaaagg aagggcagca 1500

 tcttgattcc atttatcatc cagaacctgg gcctcctgac tggattcacc 1550

 atcatggtgg tcctcaccat gtattcagga cagatccaga ttgggtaggg 1600

 ctctgccaag agcctgtggg actggaagtc gggccctggg ctgcccgatc 1650

 gccagcccga ggacttacca tccacaatgc accacggaag aggccgttct 1700

 atgaaaaact gacacagact gtattcctgc attcaaatgt cagccgtttg 1750

 taaaatgctg tatcctagga ataagctgcc ctggtaacca gtctctagct 1800

 agtgcctctt gccctctcct cacctccttt tctctcagtg actctggaac 1850

 ctgaatgcag cttacaagac aagcctgact tttttctctg attaccttgg 1900

 cctcctcttg gaaccagtgc tgaaaggttt tgaatccttt acccaacaat 1950

 gcaaaaatag agccaatggt tataacttgg ctagaaatat caagagttga 2000

 atccatagtg tggggcccat gactctagct gggcaccttg gacctccagc 2050

 tggccaatag aagagacagg agacaggaag ccttcccatt ttttcaaagt 2100

 ctgtttaatt gcctattact tctctcaaag agaacctgaa gtcagaacac 2150

 atgagcaggg tgagaggtga ggcaaggttc atcctgaatg ggagaggaag 2200

 tcgaaccact gctgtgtgtc ttgtcaggat gctcacttgt tcctactgag 2250

 atgctggata ttgattttgt aacagcacct ggtgtttcac ggctgtccga 2300

 gtgagctaac gtggcggtgt ggctgcctgg acctcctctt tcaggttaac 2350

 gctgacagaa tggaggctca ggctgtctgc aagaaaacag ttggtttggc 2400

 tgtgattttg acctcctctt ccccactgcc atcttctaag agactttgta 2450

 gctgcctcct agaagcacat tctgagcaca tttgagacct ctgtgttaga 2500

 ggggagactg cacaaactat cctcccccag gttgagacgt ctgcagagtg 2550

 gcaagctgac ttgtagaaat ggggtgccat ttatgctcta cttagacaag 2600

 ggtaatcaga aatggaatca gtgcaggcaa aatttaggat ttgccgcttc 2650

 cataaatcaa agcatgacta atagggggtc tctgaaatgt aagggcacaa 2700

 acttcactta gggcatcgca gatgtttgca gaatggttgg cctaatgatt 2750

 atgctacaga tgggttttaa atgacccgtc taggttactg cttccttgca 2800

 aaaaaagtcg aatcctgcat tgaattgaat atgaatttct ctaactctct 2850

 ccagaaaatg gatggagata acttgtcttt aaaactgtag gccagcctta 2900

 gccactgtgg agcccttgcc tccgagctct ggcttcaagg ggagctcttc 2950

 tccaggttca ctaggtgaat tgatttatta ttatcatatt gataatgtga 3000

 gattctttag ccactttggg gagcctgtct ctccagaagc ctttcttagt 3050

 ggtgcccaca gttggagccc aggggccatg tttgcaaact gattcatgtg 3100

 catggctgac aggagtactg gttcactacc aatgcctgag cttttctctt 3150

 acatagaaaa actgtccact ctcagtaatc acaagcagca tccgttttgt 3200

 tttctcttct tgggagacat ctgtcaaacc aggaatattc ttgaaaagaa 3250

 cgtgagcagg aaaaactgct ggtgatactt tttttaagtt ttgtttttat 3300

 cttgcctgtt ggcttcaata catttgagaa tacgctgaag agggaaaatt 3350

 tcagtgatgg agattctaga ttaaatatca ggactgattt cctggtggga 3400

 ttatggtcca gttttaccaa agaaccaatt ccttgaatgt tggaatctaa 3450

 ctttttatat tgtcattatt attgttgttt ttaaacggtt ctttgtcttt 3500

 tctgttttat ttttctcaag ctgctttcag gagctagcag aaaataactc 3550

 aaagttgaag actctggaag attttgcttt aacctaactc gcattgatgt 3600

 attaaattta taattttagc attcccaata gatcctatca ttccttaaac 3650

 ataataccct ttgtcttgga gtagaatact aagttagagt tagtggattt 3700

 ctagtttagg agaggagctc aaaactataa tctttaacaa attgaaaaat 3750

 gaaatagggt gttttccctt tttgtgcaca cctatattac cttaagaaat 3800

 ttccttccat agacagctgc ctcaaaggga aatcctcttt aaaccgtagt 3850

 tggcgcagag gtcagtccta gtcggagctt aggaggggcg gagacgctca 3900

 catcgtctga cttgagtcgc cactgattgt ggcaacagct ttgcctcatg 3950

 agtcaaaaat tggcaatttc ttttgatttt tagttgttga atttgctgtt 4000

 tcaagcattt gtacatatta gaagtctaag gagtagcaag tcagtgggag 4050

 gactttttca cccctggcat tagcagcttc gacctcattt tccagatgca 4100

 ccagctccta ttaataagtt agcaaggaaa gtgtatgtca cgtgcaggaa 4150

 cagtgaggca gggacagggg ttctgctcct tctcacttca ccaccggcac 4200

 acagcttgcc cctgtctttg cccccaaagg tattttgtgt ctagtgtcaa 4250

 attggagcta ttcttcactg gtccttaacc ttgggtttta aaaagaaggc 4300

 ttctctgttt gggtagcgta agagctgagt atagtaagtc ctcttccaaa 4350

 gagatggcaa tatgctgggc atctacttta aaacaaagtt gtctgatttt 4400

 tgcaagagag gttaggattt tattgttctt atttcccttt acagttctgc 4450

 agttccatca cagtattttt ttaaataact caggtgtatg agcagaaatt 4500

 agaaaagaaa attaacttat gtggactgta aatgttttat ttgtaagatt 4550

 ctataaataa agctatattc tgt 4573

<210> 2517
<211> 531
<212> PRT
<213> Homo sapien

<400> 2517
 Arg Val Tyr Ala Asp Ala Pro Ala Lys Leu Leu Leu Pro Pro Pro
   1               5                  10                  15

 Ala Ala Trp Asp Leu Ala Val Arg Leu Arg Gly Ala Glu Ala Ala
                  20                  25                  30

 Ser Glu Arg Gln Val Tyr Ser Val Thr Met Lys Leu Leu Leu Leu
                  35                  40                  45

 His Pro Ala Phe Gln Ser Cys Leu Leu Leu Thr Leu Leu Gly Leu
                  50                  55                  60

 Trp Arg Thr Thr Pro Glu Ala His Ala Ser Ser Leu Gly Ala Pro
                  65                  70                  75

 Ala Ile Ser Ala Ala Ser Phe Leu Gln Asp Leu Ile His Arg Tyr
                  80                  85                  90

 Gly Glu Gly Asp Ser Leu Thr Leu Gln Gln Leu Lys Ala Leu Leu
                  95                 100                 105

 Asn His Leu Asp Val Gly Val Gly Arg Gly Asn Val Thr Gln His
                 110                 115                 120

 Val Gln Gly His Arg Asn Leu Ser Thr Cys Phe Ser Ser Gly Asp
                 125                 130                 135

 Leu Phe Thr Ala His Asn Phe Ser Glu Gln Ser Arg Ile Gly Ser
                 140                 145                 150

 Ser Glu Leu Gln Glu Phe Cys Pro Thr Ile Leu Gln Gln Leu Asp
                 155                 160                 165

 Ser Arg Ala Cys Thr Ser Glu Asn Gln Glu Asn Glu Glu Asn Glu
                 170                 175                 180

 Gln Thr Glu Glu Gly Arg Pro Ser Ala Val Glu Val Trp Gly Tyr
                 185                 190                 195

 Gly Leu Leu Cys Val Thr Val Ile Ser Leu Cys Ser Leu Leu Gly
                 200                 205                 210

 Ala Ser Val Val Pro Phe Met Lys Lys Thr Phe Tyr Lys Arg Leu
                 215                 220                 225

 Leu Leu Tyr Phe Ile Ala Leu Ala Ile Gly Thr Leu Tyr Ser Asn
                 230                 235                 240

 Ala Leu Phe Gln Leu Ile Pro Glu Ala Phe Gly Phe Asn Pro Leu
                 245                 250                 255

 Glu Asp Tyr Tyr Val Ser Lys Ser Ala Val Val Phe Gly Gly Phe
                 260                 265                 270

 Tyr Leu Phe Phe Phe Thr Glu Lys Ile Leu Lys Ile Leu Leu Lys
                 275                 280                 285

 Gln Lys Asn Glu His His His Gly His Ser His Tyr Ala Ser Glu
                 290                 295                 300

 Ser Leu Pro Ser Lys Lys Asp Gln Glu Glu Gly Val Met Glu Lys
                 305                 310                 315

 Leu Gln Asn Gly Asp Leu Asp His Met Ile Pro Gln His Cys Ser
                 320                 325                 330

 Ser Glu Leu Asp Gly Lys Ala Pro Met Val Asp Glu Lys Val Ile
                 335                 340                 345

 Val Gly Ser Leu Ser Val Gln Asp Leu Gln Ala Ser Gln Ser Ala
                 350                 355                 360

 Cys Tyr Trp Leu Lys Gly Val Arg Tyr Ser Asp Ile Gly Thr Leu
                 365                 370                 375

 Ala Trp Met Ile Thr Leu Ser Asp Gly Leu His Asn Phe Ile Asp
                 380                 385                 390

 Gly Leu Ala Ile Gly Ala Ser Phe Thr Val Ser Val Phe Gln Gly
                 395                 400                 405

 Ile Ser Thr Ser Val Ala Ile Leu Cys Glu Glu Phe Pro His Glu
                 410                 415                 420

 Leu Gly Asp Phe Val Ile Leu Leu Asn Ala Gly Met Ser Ile Gln
                 425                 430                 435

 Gln Ala Leu Phe Phe Asn Phe Leu Ser Ala Cys Cys Cys Tyr Leu
                 440                 445                 450

 Gly Leu Ala Phe Gly Ile Leu Ala Gly Ser His Phe Ser Ala Asn
                 455                 460                 465

 Trp Ile Phe Ala Leu Ala Gly Gly Met Phe Leu Tyr Ile Ser Leu
                 470                 475                 480

 Ala Asp Met Phe Pro Glu Met Asn Glu Val Cys Gln Glu Asp Glu
                 485                 490                 495

 Arg Lys Gly Ser Ile Leu Ile Pro Phe Ile Ile Gln Asn Leu Gly
                 500                 505                 510

 Leu Leu Thr Gly Phe Thr Ile Met Val Val Leu Thr Met Tyr Ser
                 515                 520                 525

 Gly Gln Ile Gln Ile Gly
                 530

<210> 2518
<211> 1115
<212> DNA
<213> Homo sapien

<400> 2518
 gggaggtgca gaggcatccg gggcgggagc aagccccagg ttgtgacagg 50

 tgcaggtaga caacgcccat aaacagagat ggtcctgaac tctggagaga 100

 tccttccctg atcctttcgg acgactactt ggagccataa gtaacctcag 150

 caaaaacgag gcctctgcaa gccacttttc catgccaagc atccacccgg 200

 cccacaggca tgtttctgcc gccactccgc aagatggaca gggagccagc 250

 aggcaggcgg gaagggccaa gtacaggcaa tcacccccat cttcttggtt 300

 tgaagcttta tccatgtatc atgttccgtg tagccatttt attttttaag 350

 aaactgctaa tactttctcc ctaatggaag ccctgatccc ccagagagct 400

 acaggtctgc tcccgacggg cctcgggcct gacccgtcca cacagggccg 450

 tgtcaacagc agcgactcaa gggacgtgtg tacatatgta aatgagaaat 500

 agagacgtgt caacagatgc attcatttct cttggaatgt gtattgtttt 550

 tattttgcga aacaaaacaa aacaaaaaaa aaagcttgga actccatcac 600

 gtggaaaaac tagatcctgt tggttatagc atttgtgagt tctccacgtc 650

 tgtctctctc gctcatgtaa tatactctga ccctgagtgg aaaggggttt 700

 ttgttctgtt tttattttac ctacatgtac tatttagctt cagtgtacta 750

 gtcctgccac ctgtgtattt ttagggtgct atggaaataa tgaaaagaaa 800

 cggggatttc agaagaaaat tgtaaccaaa ttcatacttt gtataatttt 850

 tgatatcatg atcacaggtg attcacacgt acacacataa acacacccac 900

 cagtgcagcc tgaagtaact cccacagaaa ccatcatcgt ctttgtacat 950

 cgtatgtaca atgcaatcat ttcatacttt aaactggtca aaaaactaat 1000

 tgtgatttct agtcttgcaa agctgtatgt agttagatga tgtgacaacc 1050

 tctaatattt atctaataaa tatgtattca gatgaaacct gtaaaaaaaa 1100

 aaaaaaaaaa aaaaa 1115

<210> 2519
<211> 10
<212> PRT
<213> Homo sapien

<400> 2519
 Met Lys Pro Val Lys Lys Lys Lys Lys Lys
   1               5                  10

<210> 2520
<211> 3003
<212> DNA
<213> Homo sapien

<400> 2520
 ggcacgaggg gtgctggaag cgcgtgaggc cgggagctcg agagagctaa 50

 cagactagcc ggctggacat ctggaccgct ggatccggag gtggcgaccc 100

 cggcctgacc cggaccctaa atccgtcccc gccccagagg gcggaggcgc 150

 gcgctcgatt cccccaacgc ggcggcgccg cctgtttacg tctgcagatc 200

 tccaggggag cccaccagcc tagtcaacat ggcctcggaa gacattgcca 250

 agctggcaga gacacttgcc aagactcagg tggccggggg acagctgagt 300

 ttcaaaggca agagcctcaa actcaacact gcagaagatg ctaaagatgt 350

 gattaaagag attgaagact ttgacagctt ggaggctctg cgtctggaag 400

 gcaacacagt gggcgtggaa gcagccaggg tcatcgccaa ggccttagag 450

 aagaagtcgg agttgaagcg ctgccactgg agtgacatgt tcacgggaag 500

 gctgcggacc gagatcccac cagccctgat ctcactaggg gaaggactca 550

 tcacagctgg ggctcagctg gtggagctgg acttaagcga caacgcattc 600

 gggcccgacg gtgtgcaagg cttcgaggcc ctgctcaaga gctcagcctg 650

 cttcaccctg caggaactca agctcaacaa ctgtggcatg ggcattggcg 700

 gcggcaagat cctggctgca gctctgaccg aatgtcaccg gaaatccagt 750

 gcccaaggca agcctctggc cctgaaggtc tttgtggctg gcagaaaccg 800

 tctggagaat gatggcgcca ctgccttggc agaagctttt agggtcatcg 850

 ggaccctgga ggaggtccac atgccacaga atgggatcaa ccaccctggc 900

 atcactgccc tggcccaggc tttcgctgtc aaccccctgc tgcgggtcat 950

 caacctgaat gacaacacct tcactgagaa gggcgccgtg gccatggccg 1000

 agaccttgaa gaccttgcgg caggtggagg tgattaattt tggggactgc 1050

 ctggtgcgct ccaagggtgc agttgccatt gcagatgcca tccgcggcgg 1100

 cctgcccaag ctaaaggagc tgaacttgtc attctgtgaa atcaagaggg 1150

 atgctgccct ggctgttgct gaggccatgg cagacaaagc tgagctggag 1200

 aagctggacc tgaatggcaa caccctggga gaagaaggct gtgaacagct 1250

 tcaggaggtg ctggagggct tcaacatggc caaggtgctg gcgtccctca 1300

 gtgatgacga ggacgaggag gaggaggagg aaggagaaga ggaagaagag 1350

 gaagcagaag aagaggagga ggaagatgag gaagaggagg aagaagagga 1400

 ggaggaggag gaagaagagc ctcagcagcg agggcaggga gagaagtcag 1450

 ccacgccctc acggaagatt ctggacccta acactgggga gccagctccc 1500

 gtgctgtcct ccccacctcc tgcagacgtc tccaccttcc tggcttttcc 1550

 ctctccagag aagctgctgc gcctagggcc caagagctcc gtgctgatag 1600

 cccagcagac tgacacgtct gaccccgaga aggtggtctc tgccttccta 1650

 aaggtgtcat ctgtgttcaa ggacgaagct actgtgagga tggcagtgca 1700

 ggatgcagta gatgccctga tgcagaaggc tttcaactcc tcgtccttca 1750

 actccaacac cttcctcacc aggctcctcg tgcacatggg tctgctcaag 1800

 agtgaagaca aggtcaaggc cattgccaac ctgtacggcc ccctgatggc 1850

 gctgaaccac atggtgcagc aggactattt ccccaaggcc cttgcacccc 1900

 tgctgctggc gttcgtgacc aagcccaaca gcgccctgga atcctgctcc 1950

 ttcgcccgcc acagtctgct gcagacgctg tacaaggtct agactcaaag 2000

 cctctcccat cccttggcct ggaccagtga gctggggagg gactcggatg 2050

 aactgaggcg cagcctacgc cattgccttg gacaggactc tggccacagg 2100

 cagggcgggt ctgtgtccca tgtgtcctgt cagtcccctg agtatgtgtg 2150

 tgggtgtggc gcatgtgcag gtctgtgcct cctgtcggga tttgggtttt 2200

 aacgtcttct gctggcccag ccctgctctg ttgtggggag ttggccccca 2250

 ggggaaaggg ctgtgagctg ctccgccatt aaactcacct ccacctgagg 2300

 gcgctctgct gatctccgcc tgggccctga tggccgtccc cacccacctg 2350

 ccttccggcc cggctccctg gcggagccag aacccaggga gttgcccgcg 2400

 tgctgtcctt cccctctgtg ttgtgattgg gttgtttcct gccctgcctg 2450

 gggctgcttc tcgtcaccaa gccctggtcc tgcggcagct gtcaccccta 2500

 ccatccatac cactgtgctg accgctcagc ctgaagagca gagaatgcca 2550

 tgggtgggac tgtgggggtc ggatcgtggg gttgttggca gagggcaacc 2600

 ctgggcccca caccgtgtgg acaggcagac accagattgt ccaggagcag 2650

 gagctgctgg gactgcgctg gccccggacc tagtgggcct tctcctggct 2700

 gctgagatgt cgtctgtgac tggcctggct ggagggggag tgttgacaac 2750

 ccaaagctgt tctccagtct ggggagggag aggcagggtc cccaatgtcc 2800

 gagctgcatc tggacgctgc tcttaaagga cctcctgggg caggggagcg 2850

 gtagggtctg gactgggcag atgctgtatg acctccctga gcacccgtga 2900

 ctgccccatg ctttcccctt tgtgctctgt gtgtgtctgg gctgtgcccg 2950

 ggggcttcac aaataaagtc gtgtggcagc ttcaaaaaaa aaaaaaaaaa 3000

 aaa 3003

<210> 2521
<211> 587
<212> PRT
<213> Homo sapien

<400> 2521
 Met Ala Ser Glu Asp Ile Ala Lys Leu Ala Glu Thr Leu Ala Lys
   1               5                  10                  15

 Thr Gln Val Ala Gly Gly Gln Leu Ser Phe Lys Gly Lys Ser Leu
                  20                  25                  30

 Lys Leu Asn Thr Ala Glu Asp Ala Lys Asp Val Ile Lys Glu Ile
                  35                  40                  45

 Glu Asp Phe Asp Ser Leu Glu Ala Leu Arg Leu Glu Gly Asn Thr
                  50                  55                  60

 Val Gly Val Glu Ala Ala Arg Val Ile Ala Lys Ala Leu Glu Lys
                  65                  70                  75

 Lys Ser Glu Leu Lys Arg Cys His Trp Ser Asp Met Phe Thr Gly
                  80                  85                  90

 Arg Leu Arg Thr Glu Ile Pro Pro Ala Leu Ile Ser Leu Gly Glu
                  95                 100                 105

 Gly Leu Ile Thr Ala Gly Ala Gln Leu Val Glu Leu Asp Leu Ser
                 110                 115                 120

 Asp Asn Ala Phe Gly Pro Asp Gly Val Gln Gly Phe Glu Ala Leu
                 125                 130                 135

 Leu Lys Ser Ser Ala Cys Phe Thr Leu Gln Glu Leu Lys Leu Asn
                 140                 145                 150

 Asn Cys Gly Met Gly Ile Gly Gly Gly Lys Ile Leu Ala Ala Ala
                 155                 160                 165

 Leu Thr Glu Cys His Arg Lys Ser Ser Ala Gln Gly Lys Pro Leu
                 170                 175                 180

 Ala Leu Lys Val Phe Val Ala Gly Arg Asn Arg Leu Glu Asn Asp
                 185                 190                 195

 Gly Ala Thr Ala Leu Ala Glu Ala Phe Arg Val Ile Gly Thr Leu
                 200                 205                 210

 Glu Glu Val His Met Pro Gln Asn Gly Ile Asn His Pro Gly Ile
                 215                 220                 225

 Thr Ala Leu Ala Gln Ala Phe Ala Val Asn Pro Leu Leu Arg Val
                 230                 235                 240

 Ile Asn Leu Asn Asp Asn Thr Phe Thr Glu Lys Gly Ala Val Ala
                 245                 250                 255

 Met Ala Glu Thr Leu Lys Thr Leu Arg Gln Val Glu Val Ile Asn
                 260                 265                 270

 Phe Gly Asp Cys Leu Val Arg Ser Lys Gly Ala Val Ala Ile Ala
                 275                 280                 285

 Asp Ala Ile Arg Gly Gly Leu Pro Lys Leu Lys Glu Leu Asn Leu
                 290                 295                 300

 Ser Phe Cys Glu Ile Lys Arg Asp Ala Ala Leu Ala Val Ala Glu
                 305                 310                 315

 Ala Met Ala Asp Lys Ala Glu Leu Glu Lys Leu Asp Leu Asn Gly
                 320                 325                 330

 Asn Thr Leu Gly Glu Glu Gly Cys Glu Gln Leu Gln Glu Val Leu
                 335                 340                 345

 Glu Gly Phe Asn Met Ala Lys Val Leu Ala Ser Leu Ser Asp Asp
                 350                 355                 360

 Glu Asp Glu Glu Glu Glu Glu Glu Gly Glu Glu Glu Glu Glu Glu
                 365                 370                 375

 Ala Glu Glu Glu Glu Glu Glu Asp Glu Glu Glu Glu Glu Glu Glu
                 380                 385                 390

 Glu Glu Glu Glu Glu Glu Glu Pro Gln Gln Arg Gly Gln Gly Glu
                 395                 400                 405

 Lys Ser Ala Thr Pro Ser Arg Lys Ile Leu Asp Pro Asn Thr Gly
                 410                 415                 420

 Glu Pro Ala Pro Val Leu Ser Ser Pro Pro Pro Ala Asp Val Ser
                 425                 430                 435

 Thr Phe Leu Ala Phe Pro Ser Pro Glu Lys Leu Leu Arg Leu Gly
                 440                 445                 450

 Pro Lys Ser Ser Val Leu Ile Ala Gln Gln Thr Asp Thr Ser Asp
                 455                 460                 465

 Pro Glu Lys Val Val Ser Ala Phe Leu Lys Val Ser Ser Val Phe
                 470                 475                 480

 Lys Asp Glu Ala Thr Val Arg Met Ala Val Gln Asp Ala Val Asp
                 485                 490                 495

 Ala Leu Met Gln Lys Ala Phe Asn Ser Ser Ser Phe Asn Ser Asn
                 500                 505                 510

 Thr Phe Leu Thr Arg Leu Leu Val His Met Gly Leu Leu Lys Ser
                 515                 520                 525

 Glu Asp Lys Val Lys Ala Ile Ala Asn Leu Tyr Gly Pro Leu Met
                 530                 535                 540

 Ala Leu Asn His Met Val Gln Gln Asp Tyr Phe Pro Lys Ala Leu
                 545                 550                 555

 Ala Pro Leu Leu Leu Ala Phe Val Thr Lys Pro Asn Ser Ala Leu
                 560                 565                 570

 Glu Ser Cys Ser Phe Ala Arg His Ser Leu Leu Gln Thr Leu Tyr
                 575                 580                 585

 Lys Val


<210> 2522
<211> 451
<212> DNA
<213> Homo sapien

<400> 2522
 aggaccacgc ctcctccaag tcccagcgaa cccgcgtgca acctgtcccg 50

 actctagccg cctcttcagc tcgccatgga tcccaactgc tcctgcgccg 100

 ccggtgactc ctgcacctgc gccggctcct gcaaatgcaa agagtgcaaa 150

 tgcacctcct gcaagaaaag ctgctgctcc tgctgccctg tgggctgtgc 200

 caagtgtgcc cagggctgca tctgcaaagg ggcgtcggac aagtgcagct 250

 gctgcgcctg atgctgggac agccccgctc ccagatgtaa agaacgcgac 300

 ttccacaaac ctggattttt tatgtacaac cctgaccgtg accgtttgct 350

 atattccttt ttctatgaaa taatgtgaat gataataaaa cagctttgac 400

 ttgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 450

 a 451

<210> 2523
<211> 61
<212> PRT
<213> Homo sapien

<400> 2523
 Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Asp Ser Cys Thr Cys
   1               5                  10                  15

 Ala Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ala Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Ile Cys Lys Gly Ala Ser Asp Lys Cys Ser Cys Cys
                  50                  55                  60

 Ala


<210> 2524
<211> 2129
<212> DNA
<213> Homo sapien

<400> 2524
 ggcacgaggg ctgcccgggc tgcgcggcgt ctgcaggcgc caccgctgcc 50

 tctttccggc tgtgaccctc ctcgccggcg ccgcttggct gcgtcctccg 100

 actccccgcg ccgccgagac caggctcccg ctccggttgc ggccgcaccg 150

 ccctccgcgg ccgccccctg gggatccagc gagcgcggtc gtccttggtg 200

 gaaggaacca tgaactggca tctccccctc ttcctcttgg cctctgtgac 250

 gctgccttcc atctgctccc acttcaatcc tctgtctctc gaggaactag 300

 gctccaacac ggggatccag gttttcaatc agattgtgaa gtcgaggcct 350

 catgacaaca tcgtgatctc tccccatggg attgcgtcgg tcctggggat 400

 gcttcagctg ggggcggacg gcaggaccaa gaagcagctc gccatggtga 450

 tgagatacgg cgtaaatgga gttggtaaaa tattaaagaa gatcaacaag 500

 gccatcgtct ccaagaagaa taaagacatt gtgacagtgg ctaacgccgt 550

 gtttgttaag aatgcctctg aaattgaagt gccttttgtt acaaggaaca 600

 aagatgtgtt ccagtgtgag gtccggaatg tgaactttga ggatccagcc 650

 tctgcctgtg attccatcaa tgcatgggtt aaaaatgaaa ccagggatat 700

 gattgacaat ctgctgtccc cagatcttat tgatggtgtg ctcaccagac 750

 tggtcctcgt caacgcagtg tatttcaagg gtctgtggaa atcacggttc 800

 caacccgaga acacaaagaa acgcactttc gtggcagccg acgggaaatc 850

 ctatcaagtg ccaatgctgg cccagctctc cgtgttccgg tgtgggtcga 900

 caagtgcccc caatgattta tggtacaact tcattgaact gccctaccac 950

 ggggaaagca tcagcatgct gattgcactg ccgactgaga gctccactcc 1000

 gctgtctgcc atcatcccac acatcagcac caagaccata gacagctgga 1050

 tgagcatcat ggtgcccaag agggtgcagg tgatcctgcc caagttcaca 1100

 gctgtagcac aaacagattt gaaggagccg ctgaaagttc ttggcattac 1150

 tgacatgttt gattcatcaa aggcaaattt tgcaaaaata acaacagggt 1200

 cagaaaacct ccatgtttct catatcttgc aaaaagcaaa aattgaagtc 1250

 agtgaagatg gaaccaaagc ttcagcagca acaactgcaa ttctcattgc 1300

 aagatcatcg cctccctggt ttatagtaga cagacctttt ctgtttttca 1350

 tccgacataa tcctacaggt gctgtgttat tcatggggca gataaacaaa 1400

 ccctgaagag tatacaaaag aaaccatgca aagcaacgac tactttgcta 1450

 cgaagaaaga ctcctttcct gcatctttca tagttctgtt aaatattttt 1500

 gtacatcgct tctttttcaa aactagttct taggaacaga ctcgatgcaa 1550

 gtgtttctgt tctgggaggt attggaggga aaaaacagca ggatggctgg 1600

 aacactgtac tgaggaatga atagaaaggc ttccagatgt ctaaaagatt 1650

 ctttaaacta ctgaactgtt acctaggtta acaaccctgt tgagtatttg 1700

 ctgtttgtcc agttcaggaa tttttgtttt gttttgtcta tatgtgcggc 1750

 ttttcagaag aaatttaatc agtgtgacag aaaaaaaaaa tgttttatgg 1800

 tagcttttac tttttatgaa aaaaaaatta tttgcctttt aaattctttt 1850

 cccccatccc cctccaaagt cttgatagca agcgttattt tgggggtaga 1900

 aacggtgaaa tctctagcct ctttgtgttt ttgttgttgt tgttgttgtt 1950

 gttttatata atgcatgtat tcactaaaat aaaatttaaa aaactcctgt 2000

 cttgctagac aaggttgctg ttgtgcagtg tgcctgtcac tactggtctg 2050

 tactccttgg atttgcattt ttgtattttg tacaaagtaa aaataaactg 2100

 ttatgagtag taaaaaaaaa aaaaaaaaa 2129

<210> 2525
<211> 398
<212> PRT
<213> Homo sapien

<400> 2525
 Met Asn Trp His Leu Pro Leu Phe Leu Leu Ala Ser Val Thr Leu
   1               5                  10                  15

 Pro Ser Ile Cys Ser His Phe Asn Pro Leu Ser Leu Glu Glu Leu
                  20                  25                  30

 Gly Ser Asn Thr Gly Ile Gln Val Phe Asn Gln Ile Val Lys Ser
                  35                  40                  45

 Arg Pro His Asp Asn Ile Val Ile Ser Pro His Gly Ile Ala Ser
                  50                  55                  60

 Val Leu Gly Met Leu Gln Leu Gly Ala Asp Gly Arg Thr Lys Lys
                  65                  70                  75

 Gln Leu Ala Met Val Met Arg Tyr Gly Val Asn Gly Val Gly Lys
                  80                  85                  90

 Ile Leu Lys Lys Ile Asn Lys Ala Ile Val Ser Lys Lys Asn Lys
                  95                 100                 105

 Asp Ile Val Thr Val Ala Asn Ala Val Phe Val Lys Asn Ala Ser
                 110                 115                 120

 Glu Ile Glu Val Pro Phe Val Thr Arg Asn Lys Asp Val Phe Gln
                 125                 130                 135

 Cys Glu Val Arg Asn Val Asn Phe Glu Asp Pro Ala Ser Ala Cys
                 140                 145                 150

 Asp Ser Ile Asn Ala Trp Val Lys Asn Glu Thr Arg Asp Met Ile
                 155                 160                 165

 Asp Asn Leu Leu Ser Pro Asp Leu Ile Asp Gly Val Leu Thr Arg
                 170                 175                 180

 Leu Val Leu Val Asn Ala Val Tyr Phe Lys Gly Leu Trp Lys Ser
                 185                 190                 195

 Arg Phe Gln Pro Glu Asn Thr Lys Lys Arg Thr Phe Val Ala Ala
                 200                 205                 210

 Asp Gly Lys Ser Tyr Gln Val Pro Met Leu Ala Gln Leu Ser Val
                 215                 220                 225

 Phe Arg Cys Gly Ser Thr Ser Ala Pro Asn Asp Leu Trp Tyr Asn
                 230                 235                 240

 Phe Ile Glu Leu Pro Tyr His Gly Glu Ser Ile Ser Met Leu Ile
                 245                 250                 255

 Ala Leu Pro Thr Glu Ser Ser Thr Pro Leu Ser Ala Ile Ile Pro
                 260                 265                 270

 His Ile Ser Thr Lys Thr Ile Asp Ser Trp Met Ser Ile Met Val
                 275                 280                 285

 Pro Lys Arg Val Gln Val Ile Leu Pro Lys Phe Thr Ala Val Ala
                 290                 295                 300

 Gln Thr Asp Leu Lys Glu Pro Leu Lys Val Leu Gly Ile Thr Asp
                 305                 310                 315

 Met Phe Asp Ser Ser Lys Ala Asn Phe Ala Lys Ile Thr Thr Gly
                 320                 325                 330

 Ser Glu Asn Leu His Val Ser His Ile Leu Gln Lys Ala Lys Ile
                 335                 340                 345

 Glu Val Ser Glu Asp Gly Thr Lys Ala Ser Ala Ala Thr Thr Ala
                 350                 355                 360

 Ile Leu Ile Ala Arg Ser Ser Pro Pro Trp Phe Ile Val Asp Arg
                 365                 370                 375

 Pro Phe Leu Phe Phe Ile Arg His Asn Pro Thr Gly Ala Val Leu
                 380                 385                 390

 Phe Met Gly Gln Ile Asn Lys Pro
                 395

<210> 2526
<211> 1110
<212> DNA
<213> Homo sapien

<400> 2526
 ctttccgctc ggctgttttc ctgcgcagga gccgcagggc cgtaggcagc 50

 catggcgccc agccggaatg gcatggtctt gaagccccac ttccacaagg 100

 actggcagcg gcgcgtggcc acgtggttca accagccggc ccgtaagatc 150

 cgcagacgta aggcccggca agccaaggcg cgccgcatcg ccccgcgccc 200

 cgcgtcgggt cccatccggc ccatcgtgcg ctgccccacg gttcggtacc 250

 acacgaaggt gcgcgccggc cgcggcttca gcctggagga gctcagggtg 300

 gccggcattc acaagaaggt ggcccggacc atcggcattt ctgtggatcc 350

 gaggaggcgg aacaagtcca cggagtccct gcaggccaac gtgcagcggc 400

 tgaaggagta ccgctccaaa ctcatcctct tccccaggaa gccctcggcc 450

 cccaagaagg gagacagttc tgctgaagaa ctgaaactgg ccacccagct 500

 gaccggaccg gtcatgcccg tccggaacgt ctataagaag gagaaagctc 550

 gagtcatcac tgaggaagag aagaatttca aagccttcgc tagtctccgt 600

 atggcccgtg ccaacgcccg gctcttcggc atacgggcaa aaagagccaa 650

 ggaagccgca gaacaggatg ttgaaaagaa aaaataaagc cctcctgggg 700

 acttggaatc agtcggcagt catgctgggt ctccacgtgg tgtgtttcgt 750

 gggaacaact gggcctggga tggggcttca ctgctgtgac ttcctcctgc 800

 caggggattt ggggctttct tgaaagacag tccaagccct ggataatgct 850

 ttactttctg tgttgaagca ctgttggttg tttggttagt gactgatgta 900

 aaacggtttt cttgtgggga ggttacagag gctgacttca gagtggactt 950

 gtgttttttc tttttaaaga ggcaaggttg ggctggtgct cacagctgta 1000

 atcccagcac tttgaggttg gctgggagtt caagaccagc ctggccaaca 1050

 tgtcagaact actaaaaata aagaaatcag ccatgaaaaa aaaaaaaaaa 1100

 aaaaaaaaaa 1110

<210> 2527
<211> 211
<212> PRT
<213> Homo sapien

<400> 2527
 Met Ala Pro Ser Arg Asn Gly Met Val Leu Lys Pro His Phe His
   1               5                  10                  15

 Lys Asp Trp Gln Arg Arg Val Ala Thr Trp Phe Asn Gln Pro Ala
                  20                  25                  30

 Arg Lys Ile Arg Arg Arg Lys Ala Arg Gln Ala Lys Ala Arg Arg
                  35                  40                  45

 Ile Ala Pro Arg Pro Ala Ser Gly Pro Ile Arg Pro Ile Val Arg
                  50                  55                  60

 Cys Pro Thr Val Arg Tyr His Thr Lys Val Arg Ala Gly Arg Gly
                  65                  70                  75

 Phe Ser Leu Glu Glu Leu Arg Val Ala Gly Ile His Lys Lys Val
                  80                  85                  90

 Ala Arg Thr Ile Gly Ile Ser Val Asp Pro Arg Arg Arg Asn Lys
                  95                 100                 105

 Ser Thr Glu Ser Leu Gln Ala Asn Val Gln Arg Leu Lys Glu Tyr
                 110                 115                 120

 Arg Ser Lys Leu Ile Leu Phe Pro Arg Lys Pro Ser Ala Pro Lys
                 125                 130                 135

 Lys Gly Asp Ser Ser Ala Glu Glu Leu Lys Leu Ala Thr Gln Leu
                 140                 145                 150

 Thr Gly Pro Val Met Pro Val Arg Asn Val Tyr Lys Lys Glu Lys
                 155                 160                 165

 Ala Arg Val Ile Thr Glu Glu Glu Lys Asn Phe Lys Ala Phe Ala
                 170                 175                 180

 Ser Leu Arg Met Ala Arg Ala Asn Ala Arg Leu Phe Gly Ile Arg
                 185                 190                 195

 Ala Lys Arg Ala Lys Glu Ala Ala Glu Gln Asp Val Glu Lys Lys
                 200                 205                 210

 Lys


<210> 2528
<211> 7820
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4012-4049
<223> Unknown base

<400> 2528
 gcgccccgcc ccgccgcggg actggggtgg cgcgctacct ctgcggagaa 50

 ggatctgaca gtgttccgga gccggggcga gcagccaaaa ggcccgcgga 100

 gtcgcgctgg gccgccccgg cgcagctgaa ccgggggccg cgcctgccag 150

 gccgacgggt ctggcccagc ctggcgccaa ggggttcgtg cgctgtggag 200

 acgcggaggg tcgaggcggc gcggcctgag tgaaacccaa tggaaaaagc 250

 atgacattta gaagtagaag acttagcttc aaatccctac tccttcactt 300

 actaattttg tgatttggaa atatccgcgc aagatgttga cgttgcagac 350

 ttggctagtg caagccttgt ttattttcct caccactgaa tctacaggtg 400

 aacttctaga tccatgtggt tatatcagtc ctgaatctcc agttgtacaa 450

 cttcattcta atttcactgc agtttgtgtg ctaaaggaaa aatgtatgga 500

 ttattttcat gtaaatgcta attacattgt ctggaaaaca aaccatttta 550

 ctattcctaa ggagcaatat actatcataa acagaacagc atccagtgtc 600

 acctttacag atatagcttc attaaatatt cagctcactt gcaacattct 650

 tacattcgga cagcttgaac agaatgttta tggaatcaca ataatttcag 700

 gcttgcctcc agaaaaacct aaaaatttga gttgcattgt gaacgagggg 750

 aagaaaatga ggtgtgagtg ggatggtgga agggaaacac acttggagac 800

 aaacttcact ttaaaatctg aatgggcaac acacaagttt gctgattgca 850

 aagcaaaacg tgacaccccc acctcatgca ctgttgatta ttctactgtg 900

 tattttgtca acattgaagt ctgggtagaa gcagagaatg cccttgggaa 950

 ggttacatca gatcatatca attttgatcc tgtatataaa gtgaagccca 1000

 atccgccaca taatttatca gtgatcaact cagaggaact gtctagtatc 1050

 ttaaaattga catggaccaa cccaagtatt aagagtgtta taatactaaa 1100

 atataacatt caatatagga ccaaagatgc ctcaacttgg agccagattc 1150

 ctcctgaaga cacagcatcc acccgatctt cattcactgt ccaagacctt 1200

 aaacctttta cagaatatgt gtttaggatt cgctgtatga aggaagatgg 1250

 taagggatac tggagtgact ggagtgaaga agcaagtggg atcacctatg 1300

 aagatagacc atctaaagca ccaagtttct ggtataaaat agatccatcc 1350

 catactcaag gctacagaac tgtacaactc gtgtggaaga cattgcctcc 1400

 ttttgaagcc aatggaaaaa tcttggatta tgaagtgact ctcacaagat 1450

 ggaaatcaca tttacaaaat tacacagtta atgccacaaa actgacagta 1500

 aatctcacaa atgatcgcta tctagcaacc ctaacagtaa gaaatcttgt 1550

 tggcaaatca gatgcagctg ttttaactat ccctgcctgt gactttcaag 1600

 ctactcaccc tgtaatggat cttaaagcat tccccaaaga taacatgctt 1650

 tgggtggaat ggactactcc aagggaatct gtaaagaaat atatacttga 1700

 gtggtgtgtg ttatcagata aagcaccctg tatcacagac tggcaacaag 1750

 aagatggtac cgtgcatcgc acctatttaa gagggaactt agcagagagc 1800

 aaatgctatt tgataacagt tactccagta tatgctgatg gaccaggaag 1850

 ccctgaatcc ataaaggcat accttaaaca agctccacct tccaaaggac 1900

 ctactgttcg gacaaaaaaa gtagggaaaa acgaagctgt cttagagtgg 1950

 gaccaacttc ctgttgatgt tcagaatgga tttatcagaa attatactat 2000

 attttataga accatcattg gaaatgaaac tgctgtgaat gtggattctt 2050

 cccacacaga atatacattg tcctctttga ctagtgacac attgtacatg 2100

 gtacgaatgg cagcatacac agatgaaggt gggaaggatg gtccagaatt 2150

 cacttttact accccaaagt ttgctcaagg agaaattgaa gccatagtcg 2200

 tgcctgtttg cttagcattc ctattgacaa ctcttctggg agtgctgttc 2250

 tgctttaata agcgagacct aattaaaaaa cacatctggc ctaatgttcc 2300

 agatccttca aagagtcata ttgcccagtg gtcacctcac actcctccaa 2350

 ggcacaattt taattcaaaa gatcaaatgt attcagatgg caatttcact 2400

 gatgtaagtg ttgtggaaat agaagcaaat gacaaaaagc cttttccaga 2450

 agatctgaaa tcattggacc tgttcaaaaa ggaaaaaatt aatactgaag 2500

 gacacagcag tggtattggg gggtcttcat gcatgtcatc ttctaggcca 2550

 agcatttcta gcagtgatga aaatgaatct tcacaaaaca cttcgagcac 2600

 tgtccagtat tctaccgtgg tacacagtgg ctacagacac caagttccgt 2650

 cagtccaagt cttctcaaga tccgagtcta cccagccctt gttagattca 2700

 gaggagcggc cagaagatct acaattagta gatcatgtag atggcggtga 2750

 tggtattttg cccaggcaac agtacttcaa acagaactgc agtcagcatg 2800

 aatccagtcc agatatttca cattttgaaa ggtcaaagca agtttcatca 2850

 gtcaatgagg aagattttgt tagacttaaa cagcagattt cagatcatat 2900

 ttcacaatcc tgtggatctg ggcaaatgaa aatgtttcag gaagtttctg 2950

 cagcagatgc ttttggtcca ggtactgagg gacaagtaga aagatttgaa 3000

 acagttggca tggaggctgc gactgatgaa ggcatgccta aaagttactt 3050

 accacagact gtacggcaag gcggctacat gcctcagtga aggactagta 3100

 gttcctgcta caacttcagc agtacctata aagtaaagct aaaatgattt 3150

 tatctgtgaa ttcagatttt aaaaagtctt cactctctga agatgatcat 3200

 ttgcccttaa ggacaaaaat gaactgaagt ttcacatgag ctatttccat 3250

 tccagaatat ctgggattct actttaagca ctacataaac tgactttatc 3300

 ctcagactag ctgaatgatt ttgtgctgtt tcaggatgtt tgcactgaag 3350

 aaaaacagaa agcttatctg aaatttataa aactttttgt tttgctacat 3400

 agaaaacaga aggtatttga ataataagca gtgatatgct tagtgagcac 3450

 agctatactg attttgatta gaatagtcat cagagtggct tagggacagt 3500

 taatataaaa gaggagcaag gtgtagacca tcatctactt ctgctaaaat 3550

 aacttaaaaa gaggtccata ggccataact acatgagccc agcttttgta 3600

 atctgacaaa aaaatgagga gcagcttcgt gtatatcagt gtacacggta 3650

 ttccttaggt cccttccatt ggtagtgatg ctgcgagtta ttactggaga 3700

 aaaggaattc tagagcttta acttggcaga ttaaaagtac tcatttttta 3750

 ttcatcaata attagtaatc tcactagttt tcaaaaattt gcatattatt 3800

 gacaacctct ttgaagatgc atttcacaaa ctcaacagag tgccatgata 3850

 agagctaggg atcccccaaa ctatctcaag catctaaaaa attgccattt 3900

 ttaaaggctt aaattgtagt agtaaagggg aaaacaggaa gtagtagtaa 3950

 aggggaaaaa aaaccaataa agcatctaaa aaattggcat gttaaaaggc 4000

 ttaaattgct annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna 4050

 cacacacata tcattgactt ttcttaagac ttcagagtac tgggtagatg 4100

 aacactttat acagtatata tcttcagctt aaatttgttt tgagtatttt 4150

 ttttattttt aaataagtag gcaaagattt aaattttttt atttttagta 4200

 aatgtttgag gcacactaag acaacttggg gcaatatttg ccaaaacaaa 4250

 acagaacccc aaaaaatgta catcttgttc ttagcaaata tcattattgt 4300

 agagacactt aataaagaga tggtatttta atgtctgcag ttctgaggta 4350

 gggtggaact tagttctaca ttgtgattta ggaattttta aaaccttttt 4400

 tcttcaaggg agaagtgacc caggcctcga gtttagtgct aaagccgcta 4450

 gtgtacttat gctgtcccct aaccaccacg tgcgatatgg aagcagatgc 4500

 taaatatagg ggttttctta gaaagtaaga ggaaattagc aagcgttatt 4550

 agtgattgac tactgctatc aagtgaattc aaaggaaaca ggtttttatg 4600

 ccatatttaa gttacagaaa ccaggcatgc ttagaatagt ttctagaggt 4650

 tattggagaa tagaaagcta agaaaacttg gtatacattt acaatggaaa 4700

 tataattaca ctttttactc tcagaatatt gttcacatta gacttcctgt 4750

 ttatctttta tattcttgca tttatataat gcctcatcct ttcaaagttc 4800

 tttcacatat tatatgatct tctttatgaa aaaaatagat gtttcattct 4850

 gatatattca gtttcccact ttaggcaaaa gtagattaat agaatgacga 4900

 attcaaagta gatgaggaaa atcaggcaca gagaagtaaa ggtagggata 4950

 gacccaaatt tacacaacaa gataatgaca tctccagctt ttaagttgat 5000

 catcaaaggc tgggctggat ttgtcttgct gtatgtgtca ggaaatttat 5050

 acctattaca ttttccattt tctcaaaatt taagtcacat gactaatatt 5100

 tagctgcaac tttcctcata acaaatagtg tcatgaagaa tgttgtagtg 5150

 tgaagtttgt acatttcagg gtcagatata caatatgaac tcttaatcta 5200

 caggaatgag aatggaggat cattgaaggc catgatataa acaaatttgc 5250

 atgttgaagc ctgtataaaa catggtacag tgagtgaata tacccccatc 5300

 cccaagaaca ctttatacat attaaatgga tatatgatta ctgtgcaaaa 5350

 attcattctg gaaatgaaca tatatttgag cactaatatg taatgtacac 5400

 ctgccctaag gagaaaataa attataaaac tttttacatt caaaattact 5450

 ttcccaagca tgtcttagaa taatctatgt gttgatgcat gtaaattgta 5500

 ctttaggtag gcaaagaaat ctggttattt atgtaaaaac tagtctaata 5550

 aagttagtta gtggctttat cactttaaat ctttagtgtc caaaagtggt 5600

 gtttaaagta atagcacatc agaaaacctt gtctggacaa aactagttca 5650

 ctcactgctt ctgcacctgc agttgctccc tttagggtta taaaataatg 5700

 acccaaatgt tacatgtgtt gatattataa cttgtcagtt actgatgtct 5750

 gtggtatcct accctcatct ctgaaaggga taatactgaa taattattag 5800

 aaaactataa aacttcacac tttgtaccat taaaacctaa aattttaatc 5850

 ttgtcctttt ttactatgga tcagtcggca ctcgggaaca gcagcaagga 5900

 aaaaaagcaa atttcattca catgttctgt gttcatacct cttctctacc 5950

 taattgttca tttaaatttc agccttattc cttgataagg gattttacca 6000

 catgaagtca tccagtgacc ctagctctta ttgtgaagtt agtggagtat 6050

 acttagaaat gttacaactt taaaatgtta caaaacattc attaaagctc 6100

 atatttaaag tagagcatct agtttgagaa atagaaatca attattaaag 6150

 atgtcttttt tctacccatt taactagtta aaaccatgac atgtaaatgt 6200

 agaagtagaa taatcataga attccctaaa atatttctgt ttactaacat 6250

 atattgacca agtacatcaa gcaggagaga tcttccttca ttctgttata 6300

 gtccacatca ttctaatttt gctcagttgt tattaagagc atattcctaa 6350

 accatacact tttgtttcaa taaagtttta ttttgttgag atgaataaaa 6400

 taacaaagtt ataagctgca taagacaaaa gttcaattgt tcaaaaaaaa 6450

 tttactggga tagctttcta ttacaggtat tgttagatta tattgtgctg 6500

 ataagattac tttctaaaaa atttgtactt ttctgtaaat taaaagaata 6550

 tggagtcata aaatggcaag tgttttagga ttagcctaaa attggacatt 6600

 gtcattgatt tcaaagaagg tatgaactag cagtcttaca gcctaattct 6650

 tctttggact ggtccttggc agcagttcct tttcagactc gataaacaga 6700

 attcagatga tgtaagtcaa aacaaaactt tacaaagcca agcgtattat 6750

 cttttgcatt aacctatttt tttccatcat acatgctact agtatgtgca 6800

 ttagcatgat attctcatat acattgcatt aaaaattaaa aggtggcagc 6850

 tcagggtgag ctcttctgtt gctcatttgt tcctaaattt ttaagggctt 6900

 tttctcagtc aatagtttgt acaaactggt tagtttaact tcattaccca 6950

 tttcattaaa gttgatgggt cgtgtgatga gatgcattta aggccgatag 7000

 tgatagatgt tttttttatt tcttgaacac aggctttgtc tgaatgatgt 7050

 tcttttatct cttgaacaca agctttgaat gataactaca ggttttaagt 7100

 gctgttacat taataccata atgtgatgtg ttagaaacaa agggatattt 7150

 caaaggtaga tatttgaaaa ttctctagtc tcaatatgta tgtgtattga 7200

 atatactcta aaaataaatg tgcaatttgc tagtaggaca atgcagtgac 7250

 tgactagcat taggtatgtt tcttttatat cctagctatg tcccactttc 7300

 ttctaagtgc aatcctttca tgttcacttg ctgttttacc ccatctactc 7350

 taacttcatt tggaaggctt gtctagagta tagcatgtat ttttaccttt 7400

 gcagtgaatt gcatgtgcta attgtaacca cagctatttt tatgttgaca 7450

 taactccaaa tgttatatta aatgttctat tatatattag ctctaatccc 7500

 ttaagtaaat tttaagaaat aaatacttgt tcaaattttt tttctgtatg 7550

 tggttactat catctgacta tgcatatttg taacagcatt tatcattagt 7600

 ggtgttagct aaataagcat cttagtgtaa atgagatgct tcgtgtgggt 7650

 tttgtgacat tttaaatgac ataatggaat gtgatttaaa agaaaaccag 7700

 tacactatct tggtcttaat aacatagaat ggagatggca aatttatcca 7750

 ctagttttcc agatttacta tttaatagct gaggtctgaa atcgtagcat 7800

 cctccctcct agtggacatt 7820

<210> 2529
<211> 918
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4012-4049
<223> Unknown amino acid

<400> 2529
 Met Leu Thr Leu Gln Thr Trp Leu Val Gln Ala Leu Phe Ile Phe
   1               5                  10                  15

 Leu Thr Thr Glu Ser Thr Gly Glu Leu Leu Asp Pro Cys Gly Tyr
                  20                  25                  30

 Ile Ser Pro Glu Ser Pro Val Val Gln Leu His Ser Asn Phe Thr
                  35                  40                  45

 Ala Val Cys Val Leu Lys Glu Lys Cys Met Asp Tyr Phe His Val
                  50                  55                  60

 Asn Ala Asn Tyr Ile Val Trp Lys Thr Asn His Phe Thr Ile Pro
                  65                  70                  75

 Lys Glu Gln Tyr Thr Ile Ile Asn Arg Thr Ala Ser Ser Val Thr
                  80                  85                  90

 Phe Thr Asp Ile Ala Ser Leu Asn Ile Gln Leu Thr Cys Asn Ile
                  95                 100                 105

 Leu Thr Phe Gly Gln Leu Glu Gln Asn Val Tyr Gly Ile Thr Ile
                 110                 115                 120

 Ile Ser Gly Leu Pro Pro Glu Lys Pro Lys Asn Leu Ser Cys Ile
                 125                 130                 135

 Val Asn Glu Gly Lys Lys Met Arg Cys Glu Trp Asp Gly Gly Arg
                 140                 145                 150

 Glu Thr His Leu Glu Thr Asn Phe Thr Leu Lys Ser Glu Trp Ala
                 155                 160                 165

 Thr His Lys Phe Ala Asp Cys Lys Ala Lys Arg Asp Thr Pro Thr
                 170                 175                 180

 Ser Cys Thr Val Asp Tyr Ser Thr Val Tyr Phe Val Asn Ile Glu
                 185                 190                 195

 Val Trp Val Glu Ala Glu Asn Ala Leu Gly Lys Val Thr Ser Asp
                 200                 205                 210

 His Ile Asn Phe Asp Pro Val Tyr Lys Val Lys Pro Asn Pro Pro
                 215                 220                 225

 His Asn Leu Ser Val Ile Asn Ser Glu Glu Leu Ser Ser Ile Leu
                 230                 235                 240

 Lys Leu Thr Trp Thr Asn Pro Ser Ile Lys Ser Val Ile Ile Leu
                 245                 250                 255

 Lys Tyr Asn Ile Gln Tyr Arg Thr Lys Asp Ala Ser Thr Trp Ser
                 260                 265                 270

 Gln Ile Pro Pro Glu Asp Thr Ala Ser Thr Arg Ser Ser Phe Thr
                 275                 280                 285

 Val Gln Asp Leu Lys Pro Phe Thr Glu Tyr Val Phe Arg Ile Arg
                 290                 295                 300

 Cys Met Lys Glu Asp Gly Lys Gly Tyr Trp Ser Asp Trp Ser Glu
                 305                 310                 315

 Glu Ala Ser Gly Ile Thr Tyr Glu Asp Arg Pro Ser Lys Ala Pro
                 320                 325                 330

 Ser Phe Trp Tyr Lys Ile Asp Pro Ser His Thr Gln Gly Tyr Arg
                 335                 340                 345

 Thr Val Gln Leu Val Trp Lys Thr Leu Pro Pro Phe Glu Ala Asn
                 350                 355                 360

 Gly Lys Ile Leu Asp Tyr Glu Val Thr Leu Thr Arg Trp Lys Ser
                 365                 370                 375

 His Leu Gln Asn Tyr Thr Val Asn Ala Thr Lys Leu Thr Val Asn
                 380                 385                 390

 Leu Thr Asn Asp Arg Tyr Leu Ala Thr Leu Thr Val Arg Asn Leu
                 395                 400                 405

 Val Gly Lys Ser Asp Ala Ala Val Leu Thr Ile Pro Ala Cys Asp
                 410                 415                 420

 Phe Gln Ala Thr His Pro Val Met Asp Leu Lys Ala Phe Pro Lys
                 425                 430                 435

 Asp Asn Met Leu Trp Val Glu Trp Thr Thr Pro Arg Glu Ser Val
                 440                 445                 450

 Lys Lys Tyr Ile Leu Glu Trp Cys Val Leu Ser Asp Lys Ala Pro
                 455                 460                 465

 Cys Ile Thr Asp Trp Gln Gln Glu Asp Gly Thr Val His Arg Thr
                 470                 475                 480

 Tyr Leu Arg Gly Asn Leu Ala Glu Ser Lys Cys Tyr Leu Ile Thr
                 485                 490                 495

 Val Thr Pro Val Tyr Ala Asp Gly Pro Gly Ser Pro Glu Ser Ile
                 500                 505                 510

 Lys Ala Tyr Leu Lys Gln Ala Pro Pro Ser Lys Gly Pro Thr Val
                 515                 520                 525

 Arg Thr Lys Lys Val Gly Lys Asn Glu Ala Val Leu Glu Trp Asp
                 530                 535                 540

 Gln Leu Pro Val Asp Val Gln Asn Gly Phe Ile Arg Asn Tyr Thr
                 545                 550                 555

 Ile Phe Tyr Arg Thr Ile Ile Gly Asn Glu Thr Ala Val Asn Val
                 560                 565                 570

 Asp Ser Ser His Thr Glu Tyr Thr Leu Ser Ser Leu Thr Ser Asp
                 575                 580                 585

 Thr Leu Tyr Met Val Arg Met Ala Ala Tyr Thr Asp Glu Gly Gly
                 590                 595                 600

 Lys Asp Gly Pro Glu Phe Thr Phe Thr Thr Pro Lys Phe Ala Gln
                 605                 610                 615

 Gly Glu Ile Glu Ala Ile Val Val Pro Val Cys Leu Ala Phe Leu
                 620                 625                 630

 Leu Thr Thr Leu Leu Gly Val Leu Phe Cys Phe Asn Lys Arg Asp
                 635                 640                 645

 Leu Ile Lys Lys His Ile Trp Pro Asn Val Pro Asp Pro Ser Lys
                 650                 655                 660

 Ser His Ile Ala Gln Trp Ser Pro His Thr Pro Pro Arg His Asn
                 665                 670                 675

 Phe Asn Ser Lys Asp Gln Met Tyr Ser Asp Gly Asn Phe Thr Asp
                 680                 685                 690

 Val Ser Val Val Glu Ile Glu Ala Asn Asp Lys Lys Pro Phe Pro
                 695                 700                 705

 Glu Asp Leu Lys Ser Leu Asp Leu Phe Lys Lys Glu Lys Ile Asn
                 710                 715                 720

 Thr Glu Gly His Ser Ser Gly Ile Gly Gly Ser Ser Cys Met Ser
                 725                 730                 735

 Ser Ser Arg Pro Ser Ile Ser Ser Ser Asp Glu Asn Glu Ser Ser
                 740                 745                 750

 Gln Asn Thr Ser Ser Thr Val Gln Tyr Ser Thr Val Val His Ser
                 755                 760                 765

 Gly Tyr Arg His Gln Val Pro Ser Val Gln Val Phe Ser Arg Ser
                 770                 775                 780

 Glu Ser Thr Gln Pro Leu Leu Asp Ser Glu Glu Arg Pro Glu Asp
                 785                 790                 795

 Leu Gln Leu Val Asp His Val Asp Gly Gly Asp Gly Ile Leu Pro
                 800                 805                 810

 Arg Gln Gln Tyr Phe Lys Gln Asn Cys Ser Gln His Glu Ser Ser
                 815                 820                 825

 Pro Asp Ile Ser His Phe Glu Arg Ser Lys Gln Val Ser Ser Val
                 830                 835                 840

 Asn Glu Glu Asp Phe Val Arg Leu Lys Gln Gln Ile Ser Asp His
                 845                 850                 855

 Ile Ser Gln Ser Cys Gly Ser Gly Gln Met Lys Met Phe Gln Glu
                 860                 865                 870

 Val Ser Ala Ala Asp Ala Phe Gly Pro Gly Thr Glu Gly Gln Val
                 875                 880                 885

 Glu Arg Phe Glu Thr Val Gly Met Glu Ala Ala Thr Asp Glu Gly
                 890                 895                 900

 Met Pro Lys Ser Tyr Leu Pro Gln Thr Val Arg Gln Gly Gly Tyr
                 905                 910                 915

 Met Pro Gln


<210> 2530
<211> 1324
<212> DNA
<213> Homo sapien

<400> 2530
 cggcacgagc gccgccgagg attcagcagc ctcccccttg agccccctcg 50

 cttcccgacg ttccgttccc ccctgcccgc cttctcccgc caccgccgcc 100

 gccgccttcc gcaggccgtt tccaccgagg aaaaggaatc gtatcgtatg 150

 tccgctatcc agaacctcca ctctttcgac ccctttgctg atgcaagtaa 200

 gggtgatgac ctgcttcctg ctggcactga ggattatatc catataagaa 250

 ttcaacagag aaacggcagg aagaccctta ctactgtcca agggatcgct 300

 gatgattacg ataaaaagaa actagtgaag gcgtttaaga aaaagtttgc 350

 ctgcaatggt actgtaattg agcatccgga atatggagaa gtaattcagc 400

 tacagggtga ccaacgcaag aacatatgcc agttcctcgt agagattgga 450

 ctggctaagg acgatcagct gaaggttcat gggttttaag tgcttgtggc 500

 tcactgaagc ttaagtgagg atttccttgc aatgagtaga atttcccttc 550

 tctcccttgt cacaggttta aaaacctcac agcttgtata atgtaaccat 600

 ttggggtccg cttttaactt ggactagtgt aactccttca tgcaataaac 650

 tgaaaagagc catgctgtct agtcttgaag tccctcattt aaacagaggt 700

 caagcaatag gcgcctggca gtgtcaagcc tgaaaccaag caataccgtc 750

 atgtttcagc caagcccaga gccctaagat tacaaacaac tatggccgga 800

 acctcctcag ctctccctct gcagagttcc ctaccctaag agaatgttac 850

 cacctgaaca gtcctcggtg aatctgagag gagaggatgg ggtaaggcag 900

 aagcaccagc tgtactacta gaagggagct tttggtggta gatcccctgg 950

 tgtctccaac ctgactaggt ggacagagct caaagaggcc ctcttaccgc 1000

 tagcgaggtg ataggacatc tggcttgcca caaaggtctg ttcgaccaga 1050

 catatcctag ctaagggatg tccaaacatc agaatgtgag gccaaccttc 1100

 tatcagagtt aaacttttga caagggaaca aatctcaaac tgatccatca 1150

 gtcatgtagc tagctgtaga gcttgcaact taatagcagc agctgcccaa 1200

 tgccatgtga agtaacaaac tggtttttgg tttttttttc cccttcagtt 1250

 ttaatgttat gtgtaatgta tttaaaccct tatttaaata aaacttgttt 1300

 tcagaaaaaa aaaaaaaaaa aaaa 1324

<210> 2531
<211> 113
<212> PRT
<213> Homo sapien

<400> 2531
 Met Ser Ala Ile Gln Asn Leu His Ser Phe Asp Pro Phe Ala Asp
   1               5                  10                  15

 Ala Ser Lys Gly Asp Asp Leu Leu Pro Ala Gly Thr Glu Asp Tyr
                  20                  25                  30

 Ile His Ile Arg Ile Gln Gln Arg Asn Gly Arg Lys Thr Leu Thr
                  35                  40                  45

 Thr Val Gln Gly Ile Ala Asp Asp Tyr Asp Lys Lys Lys Leu Val
                  50                  55                  60

 Lys Ala Phe Lys Lys Lys Phe Ala Cys Asn Gly Thr Val Ile Glu
                  65                  70                  75

 His Pro Glu Tyr Gly Glu Val Ile Gln Leu Gln Gly Asp Gln Arg
                  80                  85                  90

 Lys Asn Ile Cys Gln Phe Leu Val Glu Ile Gly Leu Ala Lys Asp
                  95                 100                 105

 Asp Gln Leu Lys Val His Gly Phe
                 110

<210> 2532
<211> 3372
<212> DNA
<213> Homo sapien

<400> 2532
 tacaaccagg ctcaactgtt gcatggtagc agatttgcaa acatgagtgc 50

 tgaggggtac cagtacagag cgctgtatga ttataaaaag gaaagagaag 100

 aagatattga cttgcacttg ggtgacatat tgactgtgaa taaagggtcc 150

 ttagtagctc ttggattcag tgatggacag gaagccaggc ctgaagaaat 200

 tggctggtta aatggctata atgaaaccac aggggaaagg ggggactttc 250

 cgggaactta cgtagaatat attggaagga aaaaaatctc gcctcccaca 300

 ccaaagcccc ggccacctcg gcctcttcct gttgcaccag gttcttcgaa 350

 aactgaagca gatgttgaac aacaagcttt gactctcccg gatcttgcag 400

 agcagtttgc ccctcctgac attgccccgc ctcttcttat caagctcgtg 450

 gaagccattg aaaagaaagg tctggaatgt tcaactctat acagaacaca 500

 gagctccagc aacctggcag aattacgaca gcttcttgat tgtgatacac 550

 cctccgtgga cttggaaatg atcgatgtgc acgttttggc tgacgctttc 600

 aaacgctatc tcctggactt accaaatcct gtcattccag cagccgttta 650

 cagtgaaatg atttctttag ctccagaagt acaaagctcc gaagaatata 700

 ttcagctatt gaagaagctt attaggtcgc ctagcatacc tcatcagtat 750

 tggcttacgc ttcagtattt gttaaaacat ttcttcaagc tctctcaaac 800

 ctccagcaaa aatctgttga atgcaagagt actctctgaa attttcagcc 850

 ctatgctttt cagattctca gcagccagct ctgataatac tgaaaacctc 900

 ataaaagtta tagaaatttt aatctcaact gaatggaatg aacgacagcc 950

 tgcaccagca ctgcctccta aaccaccaaa acctactact gtagccaaca 1000

 acggtatgaa taacaatatg tccttacaaa atgctgaatg gtactgggga 1050

 gatatctcga gggaagaagt gaatgaaaaa cttcgagata cagcagacgg 1100

 gacctttttg gtacgagatg cgtctactaa aatgcatggt gattatactc 1150

 ttacactaag gaaaggggga aataacaaat taatcaaaat atttcatcga 1200

 gatgggaaat atggcttctc tgacccatta accttcagtt ctgtggttga 1250

 attaataaac cactaccgga atgaatctct agctcagtat aatcccaaat 1300

 tggatgtgaa attactttat ccagtatcca aataccaaca ggatcaagtt 1350

 gtcaaagaag ataatattga agctgtaggg aaaaaattac atgaatataa 1400

 cactcagttt caagaaaaaa gtcgagaata tgatagatta tatgaagaat 1450

 atacccgcac atcccaggaa atccaaatga aaaggacagc tattgaagca 1500

 tttaatgaaa ccataaaaat atttgaagaa cagtgccaga cccaagagcg 1550

 gtacagcaaa gaatacatag aaaagtttaa acgtgaaggc aatgagaaag 1600

 aaatacaaag gattatgcat aattatgata agttgaagtc tcgaatcagt 1650

 gaaattattg acagtagaag aagattggaa gaagacttga agaagcaggc 1700

 agctgagtat cgagaaattg acaaacgtat gaacagcatt aaaccagacc 1750

 ttatccagct gagaaagacg agagaccaat acttgatgtg gttgactcaa 1800

 aaaggtgttc ggcaaaagaa gttgaacgag tggttgggca atgaaaacac 1850

 tgaagaccaa tattcactgg tggaagatga tgaagatttg ccccatcatg 1900

 atgagaagac atggaatgtt ggaagcagca accgaaacaa agctgaaaac 1950

 ctgttgcgag ggaagcgaga tggcactttt cttgtccggg agagcagtaa 2000

 acagggctgc tatgcctgct ctgtagtggt ggacggcgaa gtaaagcatt 2050

 gtgtcataaa caaaacagca actggctatg gctttgccga gccctataac 2100

 ttgtacagct ctctgaaaga actggtgcta cattaccaac acacctccct 2150

 tgtgcagcac aacgactccc tcaatgtcac actagcctac ccagtatatg 2200

 cacagcagag gcgatgaagc gcttactctt tgatccttct cctgaagttc 2250

 agccaccctg aggcctctgg aaagcaaagg gctcctctcc agtctgatct 2300

 gtgaattgag ctgcagaaac gaagccatct ttctttggat gggactagag 2350

 ctttctttca caaaaaagaa gtaggggaag acatgcagcc taaggctgta 2400

 tgatgaccac acgttcctaa gctggagtgc ttatcccttc tttttctttt 2450

 tttctttggt ttaatttaaa gccacaacca catacaacac aaagagaaaa 2500

 agaaatgcaa aaatctctgc gtgcagggac aaagaggcct ttaaccatgg 2550

 tgcttgttaa tgctttctga agctttacca gctgaaagtt gggactctgg 2600

 agagcggagg agagagaggc agaagaaccc tggcctgaga aggtttggtc 2650

 cagcctggtt tagcctggat gttgctgtgc acggtggacc cagacacatc 2700

 gcactgtgga ttatttcatt ttgtaacaaa tgaacgatat gtagcagaaa 2750

 ggcacgtcca ctcacaaggg acgctttggg agaatgtcag ttcatgtatg 2800

 ttcagaagaa attctgtcat agaaagtgcc agaaagtgtt taacttgtca 2850

 aaaaacaaaa acccagcaac agaaaaatgg agtttggaaa acaggactta 2900

 aaatgacatt cagtatataa aatatgtaca taatattgga tgactaacta 2950

 tcaaatagat ggatttgtat caataccaaa tagcttctgt tttgttttgc 3000

 tgaaggctaa attcacagcg ctatgcaatt cttaattttc attaagttgt 3050

 tatttcagtt ttaaatgtac cttcagaata agcttcccca ccccagtttt 3100

 tgttgcttga aaatattgtt gtcccggatt tttgttaata ttcatttttg 3150

 ttatcctttt ttaaaaataa atgtacagga tgccagtaaa aaaaaaaatg 3200

 gcttcagaat taaaactatg aaatatttta cagtttttct tgtacagagt 3250

 acttgctgtt agcccaaggt taaaaagttc ataacagatt ttttttggac 3300

 tgttttgttg ggcagtgcct gataagcttc aaagctgctt tattcaataa 3350

 aaaaaaaacc cgaattcact gg 3372

<210> 2533
<211> 738
<212> PRT
<213> Homo sapien

<400> 2533
 Tyr Asn Gln Ala Gln Leu Leu His Gly Ser Arg Phe Ala Asn Met
   1               5                  10                  15

 Ser Ala Glu Gly Tyr Gln Tyr Arg Ala Leu Tyr Asp Tyr Lys Lys
                  20                  25                  30

 Glu Arg Glu Glu Asp Ile Asp Leu His Leu Gly Asp Ile Leu Thr
                  35                  40                  45

 Val Asn Lys Gly Ser Leu Val Ala Leu Gly Phe Ser Asp Gly Gln
                  50                  55                  60

 Glu Ala Arg Pro Glu Glu Ile Gly Trp Leu Asn Gly Tyr Asn Glu
                  65                  70                  75

 Thr Thr Gly Glu Arg Gly Asp Phe Pro Gly Thr Tyr Val Glu Tyr
                  80                  85                  90

 Ile Gly Arg Lys Lys Ile Ser Pro Pro Thr Pro Lys Pro Arg Pro
                  95                 100                 105

 Pro Arg Pro Leu Pro Val Ala Pro Gly Ser Ser Lys Thr Glu Ala
                 110                 115                 120

 Asp Val Glu Gln Gln Ala Leu Thr Leu Pro Asp Leu Ala Glu Gln
                 125                 130                 135

 Phe Ala Pro Pro Asp Ile Ala Pro Pro Leu Leu Ile Lys Leu Val
                 140                 145                 150

 Glu Ala Ile Glu Lys Lys Gly Leu Glu Cys Ser Thr Leu Tyr Arg
                 155                 160                 165

 Thr Gln Ser Ser Ser Asn Leu Ala Glu Leu Arg Gln Leu Leu Asp
                 170                 175                 180

 Cys Asp Thr Pro Ser Val Asp Leu Glu Met Ile Asp Val His Val
                 185                 190                 195

 Leu Ala Asp Ala Phe Lys Arg Tyr Leu Leu Asp Leu Pro Asn Pro
                 200                 205                 210

 Val Ile Pro Ala Ala Val Tyr Ser Glu Met Ile Ser Leu Ala Pro
                 215                 220                 225

 Glu Val Gln Ser Ser Glu Glu Tyr Ile Gln Leu Leu Lys Lys Leu
                 230                 235                 240

 Ile Arg Ser Pro Ser Ile Pro His Gln Tyr Trp Leu Thr Leu Gln
                 245                 250                 255

 Tyr Leu Leu Lys His Phe Phe Lys Leu Ser Gln Thr Ser Ser Lys
                 260                 265                 270

 Asn Leu Leu Asn Ala Arg Val Leu Ser Glu Ile Phe Ser Pro Met
                 275                 280                 285

 Leu Phe Arg Phe Ser Ala Ala Ser Ser Asp Asn Thr Glu Asn Leu
                 290                 295                 300

 Ile Lys Val Ile Glu Ile Leu Ile Ser Thr Glu Trp Asn Glu Arg
                 305                 310                 315

 Gln Pro Ala Pro Ala Leu Pro Pro Lys Pro Pro Lys Pro Thr Thr
                 320                 325                 330

 Val Ala Asn Asn Gly Met Asn Asn Asn Met Ser Leu Gln Asn Ala
                 335                 340                 345

 Glu Trp Tyr Trp Gly Asp Ile Ser Arg Glu Glu Val Asn Glu Lys
                 350                 355                 360

 Leu Arg Asp Thr Ala Asp Gly Thr Phe Leu Val Arg Asp Ala Ser
                 365                 370                 375

 Thr Lys Met His Gly Asp Tyr Thr Leu Thr Leu Arg Lys Gly Gly
                 380                 385                 390

 Asn Asn Lys Leu Ile Lys Ile Phe His Arg Asp Gly Lys Tyr Gly
                 395                 400                 405

 Phe Ser Asp Pro Leu Thr Phe Ser Ser Val Val Glu Leu Ile Asn
                 410                 415                 420

 His Tyr Arg Asn Glu Ser Leu Ala Gln Tyr Asn Pro Lys Leu Asp
                 425                 430                 435

 Val Lys Leu Leu Tyr Pro Val Ser Lys Tyr Gln Gln Asp Gln Val
                 440                 445                 450

 Val Lys Glu Asp Asn Ile Glu Ala Val Gly Lys Lys Leu His Glu
                 455                 460                 465

 Tyr Asn Thr Gln Phe Gln Glu Lys Ser Arg Glu Tyr Asp Arg Leu
                 470                 475                 480

 Tyr Glu Glu Tyr Thr Arg Thr Ser Gln Glu Ile Gln Met Lys Arg
                 485                 490                 495

 Thr Ala Ile Glu Ala Phe Asn Glu Thr Ile Lys Ile Phe Glu Glu
                 500                 505                 510

 Gln Cys Gln Thr Gln Glu Arg Tyr Ser Lys Glu Tyr Ile Glu Lys
                 515                 520                 525

 Phe Lys Arg Glu Gly Asn Glu Lys Glu Ile Gln Arg Ile Met His
                 530                 535                 540

 Asn Tyr Asp Lys Leu Lys Ser Arg Ile Ser Glu Ile Ile Asp Ser
                 545                 550                 555

 Arg Arg Arg Leu Glu Glu Asp Leu Lys Lys Gln Ala Ala Glu Tyr
                 560                 565                 570

 Arg Glu Ile Asp Lys Arg Met Asn Ser Ile Lys Pro Asp Leu Ile
                 575                 580                 585

 Gln Leu Arg Lys Thr Arg Asp Gln Tyr Leu Met Trp Leu Thr Gln
                 590                 595                 600

 Lys Gly Val Arg Gln Lys Lys Leu Asn Glu Trp Leu Gly Asn Glu
                 605                 610                 615

 Asn Thr Glu Asp Gln Tyr Ser Leu Val Glu Asp Asp Glu Asp Leu
                 620                 625                 630

 Pro His His Asp Glu Lys Thr Trp Asn Val Gly Ser Ser Asn Arg
                 635                 640                 645

 Asn Lys Ala Glu Asn Leu Leu Arg Gly Lys Arg Asp Gly Thr Phe
                 650                 655                 660

 Leu Val Arg Glu Ser Ser Lys Gln Gly Cys Tyr Ala Cys Ser Val
                 665                 670                 675

 Val Val Asp Gly Glu Val Lys His Cys Val Ile Asn Lys Thr Ala
                 680                 685                 690

 Thr Gly Tyr Gly Phe Ala Glu Pro Tyr Asn Leu Tyr Ser Ser Leu
                 695                 700                 705

 Lys Glu Leu Val Leu His Tyr Gln His Thr Ser Leu Val Gln His
                 710                 715                 720

 Asn Asp Ser Leu Asn Val Thr Leu Ala Tyr Pro Val Tyr Ala Gln
                 725                 730                 735

 Gln Arg Arg


<210> 2534
<211> 5581
<212> DNA
<213> Homo sapien

<400> 2534
 gtaagatttt taaaccaagg aatgactggg ctatctataa acccagatgc 50

 actaagtggg gagaaaagct cggagctgca gcatatcagc tttgtcaacc 100

 tgccaacagc agagcgtacc atgctgcaag gagtaataaa caaggaatta 150

 gaaaactcgc tgctggagaa cagtcaaatt aaacaccttt ttgaaaggat 200

 gagcatgtat atattgcagt tctattaaat gtagcttctt agtgaggttg 250

 gcattatgtt aaggctggta tggaagagaa ctgatgaagc aggagtggtc 300

 tggtgacatt tttctgactt gattggctgg ggcgtgtgat gtaataggtt 350

 tcagtgcagc cccttatagg ttttaaaatg aattccaaga caccattaca 400

 aagaaagccg gactcttttc ttataactga gctcagccaa ggaaactctt 450

 gcacaaatgt acaatactgt ttggaatatg gaagacctgg atttagaata 500

 tgccaagaca gatataaatt gtggcacaga cttgatgttt tatatagaaa 550

 tggacccacc agcactgcct cctaaaccac caaaacctac tactgtagcc 600

 aacaacggta tgaataacaa tatatcctta caagatgctg aatggtactg 650

 gggagatatc tcgagggaag aagtgaatga aaaacttcga gatacagcag 700

 acgggacctt tttggtacga gatgcgtcta ctaaaatgca tggtgattat 750

 actcttacac taaggaaagg gggaaataac aaattaatca aaatatttca 800

 tcgagatggg aaatatggct tctctgaccc attaaccttc agttctgtgg 850

 ttgaattaat aaaccactac cggaatgaat ctctagctca gtataatccc 900

 aaattggatg tgaaattact ttatccagta tccaaatacc aacaggatca 950

 agttgtcaaa gaagataata ttgaagctgt agggaaaaaa ttacatgaat 1000

 ataacactca gtttcaagaa aaaagtcgag aatatgatag attatatgaa 1050

 gaatataccc gcacatccca ggaaatccaa atgaaaagga cagctattga 1100

 agcatttaat gaaaccataa aaatatttga agaacagtgc cagacccaag 1150

 agcggtacag caaagaatac atagaaaagt ttaaacgtga aggcaatgag 1200

 aaagaaatac aaaggattat gcataattat gataagttga agtctcgaat 1250

 cagtgaaatt attgacagta gaagaagatt ggaagaagac ttgaagaagc 1300

 aggcagctga gtatcgagaa attgacaaac gtatgaacag cattaaacca 1350

 gaccttatcc agctgagaaa gacgagagac caatacttga tgtggttgac 1400

 tcaaaaaggt gttcggcaaa agaagttgaa cgagtggttg ggcaatgaaa 1450

 acactgaaga ccaatattca ctggtggaag atgatgaaga tttgccccat 1500

 catgatgaga agacatggaa tgttggaagc agcaaccgaa acaaagctga 1550

 aaacctgttg cgagggaagc gagatggcac ttttcttgtc cgggagagca 1600

 gtaaacaggg ctgctatgcc tgctctgtag tggtggacgg cgaagtaaag 1650

 cattgtgtca taaacaaaac agcaactggc tatggctttg ccgagcccta 1700

 taacttgtac agctctctga aagaactggt gctacattac caacacacct 1750

 cccttgtgca gcacaacgac tccctcaatg tcacactagc ctacccagta 1800

 tatgcacagc agaggcgatg aagcgcttac tctttgatcc ttctcctgaa 1850

 gttcagccac cctgaggcct ctggaaagca aagggctcct ctccagtctg 1900

 atctgtgaat tgagctgcag aaacgaagcc atctttcttt ggatgggact 1950

 agagctttct ttcacaaaaa agaagtaggg gaagacatgc agcctaaggc 2000

 tgtatgatga ccacacgttc ctaagctgga gtgcttatcc cttctttttc 2050

 tttttttctt tggtttaatt taaagccaca accacataca acacaaagag 2100

 aaaaagaaat gcaaaaatct ctgcgtgcag ggacaaagag gcctttaacc 2150

 atggtgcttg ttaatgcttt ctgaagcttt accagctgaa agttgggact 2200

 ctggagagcg gaggagagag aggcagaaga accctggcct gagaaggttt 2250

 ggtccagcct ggtttagcct ggatgttgct gtgcacggtg gacccagaca 2300

 catcgcactg tggattattt cattttgtaa caaatgaacg atatgtagca 2350

 gaaaggcacg tccactcaca agggacgctt tgggagaatg tcagttcatg 2400

 tatgttcaga agaaattctg tcatagaaag tgccagaaag tgtttaactt 2450

 gtcaaaaaac aaaaacccag caacagaaaa atggagtttg gaaaacagga 2500

 cttaaaatga cattcagtat ataaaatatg tacataatat tggatgacta 2550

 actatcaaat agatggattt gtatcaatac caaatagctt ctgttttgtt 2600

 ttgctgaagg ctaaattcac agcgctatgc aattcttaat tttcattaag 2650

 ttgttatttc agttttaaat gtaccttcag aataagcttc cccaccccag 2700

 tttttgttgc ttgaaaatat tgttgtcccg gatttttgtt aatattcatt 2750

 tttgttatcc ttttttaaaa gtaaatgtac aggatgccag taaaaaaaaa 2800

 aaaatggctt cagaattaaa actatgaaat attttacagt ttttcttgta 2850

 cagagtactt ggctgttagc ccaaggttaa aaagttcata acagattttt 2900

 tttggactgt tttgttgggc agtgcctgat aagcttcaaa gctgctttat 2950

 tcaataaaaa aaagaaatga aaaagatata tgaatatgac aaagtattgc 3000

 tgagtccaac aatgttgttt taagactctt aaaatacggt acctggcaat 3050

 gtttatttca taaagaattg tgaacttctt gaatctaggg agggggaatg 3100

 tagtgaaggg atgtatcaag tggggtggtg ggagggggag gcaaggttat 3150

 atgcactttc tcatgattta cagagaagtg aataactgca aagtgaagtt 3200

 gcttcttcta cttcagtctt ctctcacttt gatttgctag ttgttatcaa 3250

 ttaatgacaa ttacaaacct actgtatctc taatacagtg tgactggtca 3300

 ggtatttcag ttcttaggaa ggaagtgcca agtttgtttt tgggttcctg 3350

 gaacagcgct cacctttgtt tagaacactg gtttaaaggg ataatcatct 3400

 ctgtcacatt agactatcca tcatgaccag caaatactca ttttaggaaa 3450

 aaaaaaagca tgatctgaaa aatacttttg gtggtatgtt ggttaccctc 3500

 ctagctttcc atttggttta gaacataaag caaatagaca cagtcatact 3550

 gtcactgctc tggactgtgt ggagctcgct aaagtcatgg tcattgcagg 3600

 aatccaagtg gcagtccttc tcattcattc taatcattgt atgtgcttca 3650

 ctacgggggg gagaaggaaa cgttagcatc atgtttccca tttagggcag 3700

 gagtgagagg tctctcttcc tgatttagat atgcaaaagc tggtatgttc 3750

 agtaggaact gtacatgtgt tgggaggcat aaagactaat tagcaaccat 3800

 aatatggtca ctaccctaat agactaaatg aaatcttgca atttcaaatt 3850

 actctttctc catattagat ttacccacag ctatatttct gtttaagtac 3900

 tagggtgagg gttttctgtt actttgtttt ttaatgttgt tccttttgaa 3950

 agaatcagtc ttgcagctga gtgaaaaatc tgtggaatgt attatttgtc 4000

 ctctttacat gaaactactc atacttaagc aaaagtcagt cttatagcaa 4050

 gactgttagc cctcaaactt gactctactg atctgaccat ttccctctca 4100

 tcgccagaca actgacgatt tccctggttt tagtctgcgt ctctgcttta 4150

 aagttattgt gatatccttc tagatcatac acaagtctaa cagttaatta 4200

 gttaacagtt tttaaactag gtttgtgggt atttttttgg tagcacatgt 4250

 atgctattac atacaaattt ttatttctaa aatataagat ctgagattga 4300

 atattttcat taaaagctac agttttgtga atctttgtgc ttcaacattc 4350

 tttgcaagat gatacggtat ttaggcattt gccttatttt tgcatctcac 4400

 aaacataagt gcaatagatc ttttcattga acagcaaagt aggattcatc 4450

 attccatatg acttgagtta caccagacct gttctgccca atgccttttt 4500

 gattacagtg tagcttgccc accgcatttg tcgttttaga tactttgcta 4550

 gccggccact ttggatttca tcagacagtc ctaacaatat tgtctgaacg 4600

 gctgaatatg aatagataca gcagaggcac tcctgatata tgatttttat 4650

 ccatgcgtca gtttttccca cccagtgtag catcctaaag ataaagccag 4700

 aagctaagct gcagtgaggc tgtgattggg cgtagaagtg ggagcattgg 4750

 gacctcacat tacacacacg agagatcata accatgtgaa aaggcaaaaa 4800

 gcatgtgttt gcaacatctg ataacttcat ggcctttgat aaatgtatat 4850

 atgtatatgt gcatggactg tgtttccagt acacctttca gccaaaacag 4900

 atccacagta gttgttgagt tcaagtacat aaagtacata acaagcgaac 4950

 gtctagtaca attcttactt atgtgtatgg gatttttccc tttgaggttg 5000

 ctttgttttg tcttacaaag gtgaaaattg tttgtaagtg aagtgagaag 5050

 ttcatatttc tttggctttt ttgtgttttt aaaagttact ccttttaggg 5100

 agctggtctg atgacttgct tagcttggaa atccttgttt tcagtgtgtc 5150

 gagtcaaaat gtgtttatgt gagctgtcac tgtggggaac caattgcttt 5200

 gtcatatagc tggttatgaa ctagtaacat gtttgggaag tcctactgat 5250

 gttcctttgg aagaaaaaat ctgctggttt taacaactgt gcttttgcta 5300

 tgtatggtat ccaagttagt tgaaatgcag acactgagat ctgtttgagt 5350

 ttagggtcat ttttagaaag gggcagttta aagcacaatg tctcacatgg 5400

 gacaaagttc caaaatgcca aattcttatt ttttaaaaag ctagttctat 5450

 aaaatactgg tattatgggt ggggaggaaa tagaattgag tcaattggaa 5500

 agactatcca acttaacatg aaacttgtca ccatgagata gcattagctg 5550

 cccaggatgc tgctatatat atatatgtat t 5581

<210> 2535
<211> 454
<212> PRT
<213> Homo sapien

<400> 2535
 Met Tyr Asn Thr Val Trp Asn Met Glu Asp Leu Asp Leu Glu Tyr
   1               5                  10                  15

 Ala Lys Thr Asp Ile Asn Cys Gly Thr Asp Leu Met Phe Tyr Ile
                  20                  25                  30

 Glu Met Asp Pro Pro Ala Leu Pro Pro Lys Pro Pro Lys Pro Thr
                  35                  40                  45

 Thr Val Ala Asn Asn Gly Met Asn Asn Asn Ile Ser Leu Gln Asp
                  50                  55                  60

 Ala Glu Trp Tyr Trp Gly Asp Ile Ser Arg Glu Glu Val Asn Glu
                  65                  70                  75

 Lys Leu Arg Asp Thr Ala Asp Gly Thr Phe Leu Val Arg Asp Ala
                  80                  85                  90

 Ser Thr Lys Met His Gly Asp Tyr Thr Leu Thr Leu Arg Lys Gly
                  95                 100                 105

 Gly Asn Asn Lys Leu Ile Lys Ile Phe His Arg Asp Gly Lys Tyr
                 110                 115                 120

 Gly Phe Ser Asp Pro Leu Thr Phe Ser Ser Val Val Glu Leu Ile
                 125                 130                 135

 Asn His Tyr Arg Asn Glu Ser Leu Ala Gln Tyr Asn Pro Lys Leu
                 140                 145                 150

 Asp Val Lys Leu Leu Tyr Pro Val Ser Lys Tyr Gln Gln Asp Gln
                 155                 160                 165

 Val Val Lys Glu Asp Asn Ile Glu Ala Val Gly Lys Lys Leu His
                 170                 175                 180

 Glu Tyr Asn Thr Gln Phe Gln Glu Lys Ser Arg Glu Tyr Asp Arg
                 185                 190                 195

 Leu Tyr Glu Glu Tyr Thr Arg Thr Ser Gln Glu Ile Gln Met Lys
                 200                 205                 210

 Arg Thr Ala Ile Glu Ala Phe Asn Glu Thr Ile Lys Ile Phe Glu
                 215                 220                 225

 Glu Gln Cys Gln Thr Gln Glu Arg Tyr Ser Lys Glu Tyr Ile Glu
                 230                 235                 240

 Lys Phe Lys Arg Glu Gly Asn Glu Lys Glu Ile Gln Arg Ile Met
                 245                 250                 255

 His Asn Tyr Asp Lys Leu Lys Ser Arg Ile Ser Glu Ile Ile Asp
                 260                 265                 270

 Ser Arg Arg Arg Leu Glu Glu Asp Leu Lys Lys Gln Ala Ala Glu
                 275                 280                 285

 Tyr Arg Glu Ile Asp Lys Arg Met Asn Ser Ile Lys Pro Asp Leu
                 290                 295                 300

 Ile Gln Leu Arg Lys Thr Arg Asp Gln Tyr Leu Met Trp Leu Thr
                 305                 310                 315

 Gln Lys Gly Val Arg Gln Lys Lys Leu Asn Glu Trp Leu Gly Asn
                 320                 325                 330

 Glu Asn Thr Glu Asp Gln Tyr Ser Leu Val Glu Asp Asp Glu Asp
                 335                 340                 345

 Leu Pro His His Asp Glu Lys Thr Trp Asn Val Gly Ser Ser Asn
                 350                 355                 360

 Arg Asn Lys Ala Glu Asn Leu Leu Arg Gly Lys Arg Asp Gly Thr
                 365                 370                 375

 Phe Leu Val Arg Glu Ser Ser Lys Gln Gly Cys Tyr Ala Cys Ser
                 380                 385                 390

 Val Val Val Asp Gly Glu Val Lys His Cys Val Ile Asn Lys Thr
                 395                 400                 405

 Ala Thr Gly Tyr Gly Phe Ala Glu Pro Tyr Asn Leu Tyr Ser Ser
                 410                 415                 420

 Leu Lys Glu Leu Val Leu His Tyr Gln His Thr Ser Leu Val Gln
                 425                 430                 435

 His Asn Asp Ser Leu Asn Val Thr Leu Ala Tyr Pro Val Tyr Ala
                 440                 445                 450

 Gln Gln Arg Arg


<210> 2536
<211> 3213
<212> DNA
<213> Homo sapien

<400> 2536
 gaccgaagca agagctggtt caggtggcag ccacagcagc ctcagggacc 50

 tcagcaacta tggcctcctg cccagactct gataatagct gggtgcttgc 100

 tggctccgag agcctgccag tggagacact gggcccggca tccaggatgg 150

 acccagaatc tgagagagcc ctgcaggccc ctcacagccc ctccaagaca 200

 gatgggaaag aattagctgg gaccatggat ggagaaggga cgctcttcca 250

 gactgaaagc cctcagtctg gcagcattct aacagaggag actgaggtca 300

 agggcaccct ggaaggtgat gtttgtggtg tggagcctcc tggcccagga 350

 gacacagtag tccagggaga cctgcaggag accaccgtgg tgacaggcct 400

 gggaccagac acacaggacc tggaaggcca gagccctcca cagagcctgc 450

 cttcaacccc caaagcagct tggatcaggg aggagggccg ctgctccagc 500

 agtgacgatg acaccgacgt ggacatggag ggtctgcgga gacggcgggg 550

 ccgggaggcc ggcccacctc agcccatggt gcccctggct gtggagaacc 600

 aggctggggg tgagggtgca ggcggggagc tgggcatctc cctcaacatg 650

 tgcctccttg gggccctggt tctgcttggc ctgggggtcc tcctcttctc 700

 aggtggcctc tcagagtctg agactgggcc catggaggaa gtggagcggc 750

 aggtcctccc agaccccgag gtgctggaag ctgtggggga caggcaggat 800

 gggctaaggg aacagctgca ggccccagtg cctcctgaca gtgtccccag 850

 cctgcaaaac atgggtcttc tgctggacaa gctggccaag gagaaccagg 900

 acatccggct gctgcaggcc cagctgcagg cccaaaagga agagcttcag 950

 agcctgatgc accagcccaa agggctagag gaggagaatg cccagctccg 1000

 gggggctctg cagcagggcg aagccttcca gcgggctctg gagtcagagc 1050

 tgcagcagct gcgggcccgg ctccaggggc tggaggccga ctgtgtccgg 1100

 ggcccagatg gggtgtgcct cagtgggggt agaggcccac agggtgacaa 1150

 ggccatcagg gagcaaggcc ccagggagca ggagccagaa ctcagcttcc 1200

 tgaagcagaa ggaacagctg gaggctgagg cacaggcatt aaggcaagag 1250

 ttagagaggc agcgacggct gctggggtct gtacagcagg atctggagag 1300

 gagcttgcag gatgccagcc gcggggaccc agctcatgct ggcttggctg 1350

 agctgggcca cagattggcc cagaaactgc agggcctgga gaactggggc 1400

 caggaccctg gggtctctgc caatgcctca aaggcctggc accagaagtc 1450

 ccacttccag aattctaggg agtggagtgg aaaggaaaag tggtgggatg 1500

 ggcagagaga ccggaaggct gagcactgga aacataagaa ggaagaatct 1550

 ggccgggaaa ggaagaagaa ctggggaggt caggaggaca gggagccagc 1600

 aggaaggtgg aaggagggca ggccaagggt ggaggagtcg gggagcaaga 1650

 aggagggcaa gcgacagggc ccgaaggaac ccccaaggaa aagtggtagc 1700

 ttccactcct ctggagaaaa gcagaagcaa cctcggtgga gggaagggac 1750

 taaggacagc catgaccccc tgccatcctg ggcagagctg ttgaggccca 1800

 agtaccgggc accccagggc tgctcaggtg tggacgagtg tgcccggcag 1850

 gagggcctga ctttctttgg cacagagcta gccccagtgc ggcaacagga 1900

 gctggcctct ctgctaagaa catacttggc acggctgccc tgggctgggc 1950

 agctgaccaa ggagctaccc ctctcacctg ctttctttgg tgaggatggc 2000

 atcttccgtc atgaccgcct ccgcttccgg gattttgtgg atgccctgga 2050

 ggacagcttg gaggaggtgg ctgtgcaaca gacaggtgat gatgatgaag 2100

 tagatgactt tgaggacttc atcttcagcc acttctttgg agacaaagca 2150

 ctgaagaaga ggtcagggaa gaaggacaag cactcacaga gcccaagagc 2200

 tgcggggccc agggaggggc acagccatag ccaccaccac caccaccggg 2250

 gctgacaccc tgccccacag ggaatggcct tggcctggcc cagcccaaga 2300

 tcccagcgtt atctaactcc tggagggtgg actctgtcct ggcttgtttg 2350

 gtgtcctcag atatctttca cacagtagag caaaatcacc agccctgcac 2400

 tgatgtcact ttatgtagaa aaaggcctta gctggacctg cgttgccgtc 2450

 tatgcaaatg catgcaaata ctccaggccc tgggatgtgg gcttgtgttt 2500

 tgtcactgtg aagggggaga tgggagagga gcctgttttg gggtggggtc 2550

 tggggaaggc aatctgattc tgaagctaaa gagctttcat cctcttgagt 2600

 gtatgtcccc atagtgggcc ccttgaccca catgctgacc ggtgccttgg 2650

 gatttgacta gagttgctgg ctcgaggccc agcacgagga cttaccctgg 2700

 ggttttgtta ggtttggaag cagctgtccc tagggggtga agtccccccc 2750

 cttttttttt ttacccctgc ttctcccacg gcttcacctc cctatgtgaa 2800

 ctgtagactc agatcccaat aaagtgctgt tgcagctatg atgctaggtg 2850

 gtttctaagc acaggggaca ccccacaccc cctgcctgaa tggatgggtc 2900

 catcccaggc actggtactt gcccccttgt tctgtatccc cctttgccct 2950

 tgccttgccc ttccaacaaa ccctaggccc ttgagaagct gatacttctc 3000

 cttttgctca cagctgcctt ggccccaccc ctgggagatg tagcaaattg 3050

 agtgtgggtt ttggagtctg agcctcaggc tcaaatccag gccaagtgat 3100

 cttgggcaag ttaatctctg ggaactttgg gtttcttatc ctcaaaaaag 3150

 gcgatggaag ggctggggaa gtgattaaat aaaagcaacg caagaaaaaa 3200

 aaaaaaaaaa aaa 3213

<210> 2537
<211> 731
<212> PRT
<213> Homo sapien

<400> 2537
 Met Ala Ser Cys Pro Asp Ser Asp Asn Ser Trp Val Leu Ala Gly
   1               5                  10                  15

 Ser Glu Ser Leu Pro Val Glu Thr Leu Gly Pro Ala Ser Arg Met
                  20                  25                  30

 Asp Pro Glu Ser Glu Arg Ala Leu Gln Ala Pro His Ser Pro Ser
                  35                  40                  45

 Lys Thr Asp Gly Lys Glu Leu Ala Gly Thr Met Asp Gly Glu Gly
                  50                  55                  60

 Thr Leu Phe Gln Thr Glu Ser Pro Gln Ser Gly Ser Ile Leu Thr
                  65                  70                  75

 Glu Glu Thr Glu Val Lys Gly Thr Leu Glu Gly Asp Val Cys Gly
                  80                  85                  90

 Val Glu Pro Pro Gly Pro Gly Asp Thr Val Val Gln Gly Asp Leu
                  95                 100                 105

 Gln Glu Thr Thr Val Val Thr Gly Leu Gly Pro Asp Thr Gln Asp
                 110                 115                 120

 Leu Glu Gly Gln Ser Pro Pro Gln Ser Leu Pro Ser Thr Pro Lys
                 125                 130                 135

 Ala Ala Trp Ile Arg Glu Glu Gly Arg Cys Ser Ser Ser Asp Asp
                 140                 145                 150

 Asp Thr Asp Val Asp Met Glu Gly Leu Arg Arg Arg Arg Gly Arg
                 155                 160                 165

 Glu Ala Gly Pro Pro Gln Pro Met Val Pro Leu Ala Val Glu Asn
                 170                 175                 180

 Gln Ala Gly Gly Glu Gly Ala Gly Gly Glu Leu Gly Ile Ser Leu
                 185                 190                 195

 Asn Met Cys Leu Leu Gly Ala Leu Val Leu Leu Gly Leu Gly Val
                 200                 205                 210

 Leu Leu Phe Ser Gly Gly Leu Ser Glu Ser Glu Thr Gly Pro Met
                 215                 220                 225

 Glu Glu Val Glu Arg Gln Val Leu Pro Asp Pro Glu Val Leu Glu
                 230                 235                 240

 Ala Val Gly Asp Arg Gln Asp Gly Leu Arg Glu Gln Leu Gln Ala
                 245                 250                 255

 Pro Val Pro Pro Asp Ser Val Pro Ser Leu Gln Asn Met Gly Leu
                 260                 265                 270

 Leu Leu Asp Lys Leu Ala Lys Glu Asn Gln Asp Ile Arg Leu Leu
                 275                 280                 285

 Gln Ala Gln Leu Gln Ala Gln Lys Glu Glu Leu Gln Ser Leu Met
                 290                 295                 300

 His Gln Pro Lys Gly Leu Glu Glu Glu Asn Ala Gln Leu Arg Gly
                 305                 310                 315

 Ala Leu Gln Gln Gly Glu Ala Phe Gln Arg Ala Leu Glu Ser Glu
                 320                 325                 330

 Leu Gln Gln Leu Arg Ala Arg Leu Gln Gly Leu Glu Ala Asp Cys
                 335                 340                 345

 Val Arg Gly Pro Asp Gly Val Cys Leu Ser Gly Gly Arg Gly Pro
                 350                 355                 360

 Gln Gly Asp Lys Ala Ile Arg Glu Gln Gly Pro Arg Glu Gln Glu
                 365                 370                 375

 Pro Glu Leu Ser Phe Leu Lys Gln Lys Glu Gln Leu Glu Ala Glu
                 380                 385                 390

 Ala Gln Ala Leu Arg Gln Glu Leu Glu Arg Gln Arg Arg Leu Leu
                 395                 400                 405

 Gly Ser Val Gln Gln Asp Leu Glu Arg Ser Leu Gln Asp Ala Ser
                 410                 415                 420

 Arg Gly Asp Pro Ala His Ala Gly Leu Ala Glu Leu Gly His Arg
                 425                 430                 435

 Leu Ala Gln Lys Leu Gln Gly Leu Glu Asn Trp Gly Gln Asp Pro
                 440                 445                 450

 Gly Val Ser Ala Asn Ala Ser Lys Ala Trp His Gln Lys Ser His
                 455                 460                 465

 Phe Gln Asn Ser Arg Glu Trp Ser Gly Lys Glu Lys Trp Trp Asp
                 470                 475                 480

 Gly Gln Arg Asp Arg Lys Ala Glu His Trp Lys His Lys Lys Glu
                 485                 490                 495

 Glu Ser Gly Arg Glu Arg Lys Lys Asn Trp Gly Gly Gln Glu Asp
                 500                 505                 510

 Arg Glu Pro Ala Gly Arg Trp Lys Glu Gly Arg Pro Arg Val Glu
                 515                 520                 525

 Glu Ser Gly Ser Lys Lys Glu Gly Lys Arg Gln Gly Pro Lys Glu
                 530                 535                 540

 Pro Pro Arg Lys Ser Gly Ser Phe His Ser Ser Gly Glu Lys Gln
                 545                 550                 555

 Lys Gln Pro Arg Trp Arg Glu Gly Thr Lys Asp Ser His Asp Pro
                 560                 565                 570

 Leu Pro Ser Trp Ala Glu Leu Leu Arg Pro Lys Tyr Arg Ala Pro
                 575                 580                 585

 Gln Gly Cys Ser Gly Val Asp Glu Cys Ala Arg Gln Glu Gly Leu
                 590                 595                 600

 Thr Phe Phe Gly Thr Glu Leu Ala Pro Val Arg Gln Gln Glu Leu
                 605                 610                 615

 Ala Ser Leu Leu Arg Thr Tyr Leu Ala Arg Leu Pro Trp Ala Gly
                 620                 625                 630

 Gln Leu Thr Lys Glu Leu Pro Leu Ser Pro Ala Phe Phe Gly Glu
                 635                 640                 645

 Asp Gly Ile Phe Arg His Asp Arg Leu Arg Phe Arg Asp Phe Val
                 650                 655                 660

 Asp Ala Leu Glu Asp Ser Leu Glu Glu Val Ala Val Gln Gln Thr
                 665                 670                 675

 Gly Asp Asp Asp Glu Val Asp Asp Phe Glu Asp Phe Ile Phe Ser
                 680                 685                 690

 His Phe Phe Gly Asp Lys Ala Leu Lys Lys Arg Ser Gly Lys Lys
                 695                 700                 705

 Asp Lys His Ser Gln Ser Pro Arg Ala Ala Gly Pro Arg Glu Gly
                 710                 715                 720

 His Ser His Ser His His His His His Arg Gly
                 725                 730

<210> 2538
<211> 5318
<212> DNA
<213> Homo sapien

<400> 2538
 gcggccgcgg gctcccgcta accgcagcct ccactcctct ccccgcgcgc 50

 cgcgcccccg ccccgccccg cccggtctcg ccggccgagc gtccgttggt 100

 ccttgagcgc gtccgacagt ctgtctgttc gcgatcctgc cggagccccg 150

 ccgccgccgg cttggattct gaaaccttcc ttgtatccct cctgagacat 200

 ctttgctgca agatcgaggc tgtcctctgg tgagaaggtg gtgaggcttc 250

 ccgtcatatt ccagctctga acagcaacat ggggtgcaaa gtcctgctca 300

 acattgggca gcagatgctg cggcggaagg tggtggactg tagccgggag 350

 gagacgcggc tgtctcgctg cctgaacact tttgatctgg tggccctcgg 400

 ggtgggcagc acactgggtg ctggtgtcta cgtcctggct ggagctgtgg 450

 cccgtgagaa tgcaggccct gccattgtca tctccttcct gatcgctgcg 500

 ctggcctcag tgctggctgg cctgtgctat ggcgagtttg gtgctcgggt 550

 ccccaagacg ggctcagctt acctctacag ctatgtcacc gttggagagc 600

 tctgggcctt catcaccggc tggaacttaa tcctctccta catcatcggt 650

 acttcaagcg tagcgagggc ctggagcgcc accttcgacg agctgatagg 700

 cagacccatc ggggagttct cacggacaca catgactctg aacgcccccg 750

 gcgtgctggc tgaaaacccc gacatattcg cagtgatcat aattctcatc 800

 ttgacaggac ttttaactct tggtgtgaaa gagtcggcca tggtcaacaa 850

 aatattcact tgtattaacg tcctggtcct gggcttcata atggtgtcag 900

 gatttgtgaa aggatcggtt aaaaactggc agctcacgga ggaggatttt 950

 gggaacacat caggccgtct ctgtttgaac aatgacacaa aagaagggaa 1000

 gcccggtgtt ggtggattca tgcccttcgg gttctctggt gtcctgtcgg 1050

 gggcagcgac ttgcttctat gccttcgtgg gctttgactg catcgccacc 1100

 acaggtgaag aggtgaagaa cccacagaag gccatccccg tggggatcgt 1150

 ggcgtccctc ttgatctgct tcatcgccta ctttggggtg tcggctgccc 1200

 tcacgctcat gatgccctac ttctgcctgg acaataacag ccccctgccc 1250

 gacgccttta agcacgtggg ctgggaaggt gccaagtacg cagtggccgt 1300

 gggctccctc tgcgctcttt ccgccagtct tctaggttcc atgtttccca 1350

 tgcctcgggt tatctatgcc atggctgagg atggactgct atttaaattc 1400

 ttagccaacg tcaatgatag gaccaaaaca ccaataatcg ccacattagc 1450

 ctcgggtgcc gttgctgctg tgatggcctt cctctttgac ctgaaggact 1500

 tggtggacct catgtccatt ggcactctcc tggcttactc gttggtggct 1550

 gcctgtgtgt tggtcttacg gtaccagcca gagcagccta acctggtata 1600

 ccagatggcc agtacttccg acgagttaga tccagcagac caaaatgaat 1650

 tggcaagcac caatgattcc cagctggggt ttttaccaga ggcagagatg 1700

 ttctctttga aaaccatact ctcacccaaa aacatggagc cttccaaaat 1750

 ctctgggcta attgtgaaca tttcaaccag ccttatagct gttctcatca 1800

 tcaccttctg cattgtgacc gtgcttggaa gggaggctct caccaaaggg 1850

 gcgctgtggg cagtctttct gctcgcaggg tctgccctcc tctgtgccgt 1900

 ggtcacgggc gtcatctgga ggcagcccga gagcaagacc aagctctcat 1950

 ttaaggttcc cttcctgcca gtgctcccca tcctgagcat cttcgtgaac 2000

 gtctatctca tgatgcagct ggaccagggc acctgggtcc ggtttgctgt 2050

 gtggatgctg ataggcttca tcatctactt tggctatggc ctgtggcaca 2100

 gcgaggaggc gtccctggat gccgaccaag caaggactcc tgacggcaac 2150

 ttggaccagt gcaagtgacg cacagccccg ccccccggag gtggcagcag 2200

 ccccgaggga cgcccccaga ggaccgggag gcaccccacc ctccccacca 2250

 gtgcaacaga aaccacctgc gtccacaccc tcactgcagc caaaggtgca 2300

 attacttgac ctgcagcccc agcccaccct cggctctgca gccggttctc 2350

 cgggccctgg tcacctccag acagctgcct ggccggggcc actaggctgc 2400

 ggctggccac tgtgtctcct cacttctctg aacaaagcag ttcctcccct 2450

 accagctcag ccccgagctg ccgcagcctc aggcagaacg gaggtcacct 2500

 tctctcctta tcttgggaac caggccttcc tcccggggac tgttctggga 2550

 ttgaaattgt gcatactcca aactttcgca gccatcttcc cgctcagccc 2600

 cagacaccca gcaatcaagc cagatgagta ccacaaaaca gtgtgtcccc 2650

 agcagctccc caccccagag ccaaatgaca gtagtgcact taaaaaggaa 2700

 aatcaggcct gttgtccttc tccggttgca ttcagttggg tcattagggc 2750

 cggaccctgc ctgccccttg gcttctcagg gctttgctct gacaccatga 2800

 cagctgcccg gggctgaggg cagctggctc cactcaaatg aggaagaagg 2850

 gatcactccc attagggcct gctttgctta tgcatgtgtg tgcacatgca 2900

 tgtaaaccag gaccttcagc tcacggcctc caggcctggg ccagttcttg 2950

 ctgctcctgc cgtctccccc gactggctgt gtcctgagta actggaacat 3000

 gagactgtat ctgcaggact ggccccatgg tggccgagtc agaagtctgt 3050

 ttcctgtgag tcgccaccgt tcactcagtc ttgccctccc atgctttgga 3100

 gccagtctgg tggctcctgt aaggttctca aggctggtgg cagctcagtc 3150

 tggggtcagg acatgtcggg gtcatgcgtt tctggccctg acataagctg 3200

 tctggcctct ctgtgacatg atgaaattga aatcaatcca cagtccatga 3250

 aattgtgaca ctccaccaga ttaagttagg gcataacatt aacttggaaa 3300

 tggccatgtc atcacccctg cggctgtcct atagctgaga tgcgtgggtc 3350

 gcaggggagg tgatttctag gcatattgct gtcccttttg tgtatctgtc 3400

 atccggatgc ttcggacccc acgcctctgc aagtgggaga gacccgagca 3450

 tcctccccac ccccatagct ccagtgcacg ccacccccgt cttgcctggg 3500

 tcggggcctg cggccagcac catttcacac acactccttg tagatgggag 3550

 ccagaggaaa cctgaacgtg ggtggagcgt tccactgagt ctacttcagg 3600

 agacagaagg cccatgctga tgggggagga ggagggacgt gggcattttg 3650

 gacaccaggg gaaatggaaa tgctgctttc aaaacttagt ttcctttcca 3700

 tttcttccta gtctggcctt tgacacaaat ctggtagaaa gaagcctgat 3750

 aaattgaggg cacttgtacc ctccctgtgc ccccagaagg ttcttggaga 3800

 gaagtgcaag aatttgtgaa cacggcggtg gagggcgggt ggatggccat 3850

 gggctgggcc tccgtatcag gcctgctcac cttgctggga gctttattct 3900

 gatctcattt tgaatgttcc agagggagca tcataagagc ccagagctcc 3950

 gatttccaaa gagtgatatt gacatttatg gagattggtg ttgtaacata 4000

 ttttgataaa tactaactta ttttgttggg gttttggttg tctcttgtct 4050

 taggacctgg tagttatttg cttgattttt ttttccgtta ttttctacat 4100

 aggcaaagag aattcgaggg atagacagtc tccaagaaaa gtgaagtggt 4150

 gggagagaat tgcttttttc ttttttttct tttctctagt ttttctttct 4200

 ggctgagatt tccgtgcaag acagcaccca atagactatt tagagttgac 4250

 atttgacatt ttaatgggcg ccatggctca ttttgtagat tgagaaggtg 4300

 cgtctcccct gctccaagtc tcatcatgac agcgtgctga cagctgggag 4350

 tctgtggcct tcctcacgca gaggccttaa agctggacac agaagcacgc 4400

 ctaggctggg cagggatggg acccatgccc cctccttaga ggacgggctt 4450

 cctggttagg aaaggacacg tgggggtgcc ttgcataata gttcactggt 4500

 caccgtgctt ttatgagtag tgtttttgtg cacttgccag gggttttctc 4550

 tctgtgtgcg aggggagtga tttaagcaat ggtgtctgga gtaagcctta 4600

 caattttaat agactttttc ttatcatatc cctcatttct ttccctgaaa 4650

 taaaaataca cacaaaccaa aaaaaaaagg atagtttcac atctcttagt 4700

 tccctggccc aaacaagaat attcttagtt ccacgggcca ggattttcct 4750

 acatagtcag aacttacaca ttactagagg cacacccacc aaggagtatt 4800

 gtgtctactt ttatctgtgc accagccaca aatacccaca ttggaaagac 4850

 ccatttgtga tgggtaaaca tcccttcctg tctcccacaa cccctgtgac 4900

 tgccctgcat gtgttcatga cctccgaagg cccaaattca tgaagcagca 4950

 aacccagcag atctccaccc ccctgcctca ggacctctgc tgaagagggg 5000

 gatgaagtgg gtctccaggg aggcagtggg ggccttgttg gcagctggca 5050

 tcgggaagcc aggcttacag tgaggagcac gctctcgcag attgggaggg 5100

 gcttccgtcc ggaggagacc acggcctcta cacacccccc actctactta 5150

 tcatccctgc tcacacaccc ttgtccaagg ctttatgcat cggatttatt 5200

 tttccaaatc aagaggacag tgatagatgc attttcccca ggctgtctca 5250

 gaaaggtcgc taaatgtata ctgttgtctt gatttggaaa aataaatccg 5300

 atgcataaag ccttggac 5318

<210> 2539
<211> 721
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 77
<223> unknown amino acid

<400> 2539
 Gly Arg Gly Leu Pro Leu Thr Ala Ala Ser Thr Pro Leu Pro Ala
   1               5                  10                  15

 Arg Arg Ala Pro Ala Pro Pro Arg Pro Val Ser Pro Ala Glu Arg
                  20                  25                  30

 Pro Leu Val Leu Glu Arg Val Arg Gln Ser Val Cys Ser Arg Ser
                  35                  40                  45

 Cys Arg Ser Pro Ala Ala Ala Gly Leu Asp Ser Glu Thr Phe Leu
                  50                  55                  60

 Val Ser Leu Leu Arg His Leu Cys Cys Lys Ile Glu Ala Val Leu
                  65                  70                  75

 Trp Xaa Glu Gly Gly Glu Ala Ser Arg His Ile Pro Ala Leu Asn
                  80                  85                  90

 Ser Asn Met Gly Cys Lys Val Leu Leu Asn Ile Gly Gln Gln Met
                  95                 100                 105

 Leu Arg Arg Lys Val Val Asp Cys Ser Arg Glu Glu Thr Arg Leu
                 110                 115                 120

 Ser Arg Cys Leu Asn Thr Phe Asp Leu Val Ala Leu Gly Val Gly
                 125                 130                 135

 Ser Thr Leu Gly Ala Gly Val Tyr Val Leu Ala Gly Ala Val Ala
                 140                 145                 150

 Arg Glu Asn Ala Gly Pro Ala Ile Val Ile Ser Phe Leu Ile Ala
                 155                 160                 165

 Ala Leu Ala Ser Val Leu Ala Gly Leu Cys Tyr Gly Glu Phe Gly
                 170                 175                 180

 Ala Arg Val Pro Lys Thr Gly Ser Ala Tyr Leu Tyr Ser Tyr Val
                 185                 190                 195

 Thr Val Gly Glu Leu Trp Ala Phe Ile Thr Gly Trp Asn Leu Ile
                 200                 205                 210

 Leu Ser Tyr Ile Ile Gly Thr Ser Ser Val Ala Arg Ala Trp Ser
                 215                 220                 225

 Ala Thr Phe Asp Glu Leu Ile Gly Arg Pro Ile Gly Glu Phe Ser
                 230                 235                 240

 Arg Thr His Met Thr Leu Asn Ala Pro Gly Val Leu Ala Glu Asn
                 245                 250                 255

 Pro Asp Ile Phe Ala Val Ile Ile Ile Leu Ile Leu Thr Gly Leu
                 260                 265                 270

 Leu Thr Leu Gly Val Lys Glu Ser Ala Met Val Asn Lys Ile Phe
                 275                 280                 285

 Thr Cys Ile Asn Val Leu Val Leu Gly Phe Ile Met Val Ser Gly
                 290                 295                 300

 Phe Val Lys Gly Ser Val Lys Asn Trp Gln Leu Thr Glu Glu Asp
                 305                 310                 315

 Phe Gly Asn Thr Ser Gly Arg Leu Cys Leu Asn Asn Asp Thr Lys
                 320                 325                 330

 Glu Gly Lys Pro Gly Val Gly Gly Phe Met Pro Phe Gly Phe Ser
                 335                 340                 345

 Gly Val Leu Ser Gly Ala Ala Thr Cys Phe Tyr Ala Phe Val Gly
                 350                 355                 360

 Phe Asp Cys Ile Ala Thr Thr Gly Glu Glu Val Lys Asn Pro Gln
                 365                 370                 375

 Lys Ala Ile Pro Val Gly Ile Val Ala Ser Leu Leu Ile Cys Phe
                 380                 385                 390

 Ile Ala Tyr Phe Gly Val Ser Ala Ala Leu Thr Leu Met Met Pro
                 395                 400                 405

 Tyr Phe Cys Leu Asp Asn Asn Ser Pro Leu Pro Asp Ala Phe Lys
                 410                 415                 420

 His Val Gly Trp Glu Gly Ala Lys Tyr Ala Val Ala Val Gly Ser
                 425                 430                 435

 Leu Cys Ala Leu Ser Ala Ser Leu Leu Gly Ser Met Phe Pro Met
                 440                 445                 450

 Pro Arg Val Ile Tyr Ala Met Ala Glu Asp Gly Leu Leu Phe Lys
                 455                 460                 465

 Phe Leu Ala Asn Val Asn Asp Arg Thr Lys Thr Pro Ile Ile Ala
                 470                 475                 480

 Thr Leu Ala Ser Gly Ala Val Ala Ala Val Met Ala Phe Leu Phe
                 485                 490                 495

 Asp Leu Lys Asp Leu Val Asp Leu Met Ser Ile Gly Thr Leu Leu
                 500                 505                 510

 Ala Tyr Ser Leu Val Ala Ala Cys Val Leu Val Leu Arg Tyr Gln
                 515                 520                 525

 Pro Glu Gln Pro Asn Leu Val Tyr Gln Met Ala Ser Thr Ser Asp
                 530                 535                 540

 Glu Leu Asp Pro Ala Asp Gln Asn Glu Leu Ala Ser Thr Asn Asp
                 545                 550                 555

 Ser Gln Leu Gly Phe Leu Pro Glu Ala Glu Met Phe Ser Leu Lys
                 560                 565                 570

 Thr Ile Leu Ser Pro Lys Asn Met Glu Pro Ser Lys Ile Ser Gly
                 575                 580                 585

 Leu Ile Val Asn Ile Ser Thr Ser Leu Ile Ala Val Leu Ile Ile
                 590                 595                 600

 Thr Phe Cys Ile Val Thr Val Leu Gly Arg Glu Ala Leu Thr Lys
                 605                 610                 615

 Gly Ala Leu Trp Ala Val Phe Leu Leu Ala Gly Ser Ala Leu Leu
                 620                 625                 630

 Cys Ala Val Val Thr Gly Val Ile Trp Arg Gln Pro Glu Ser Lys
                 635                 640                 645

 Thr Lys Leu Ser Phe Lys Val Pro Phe Leu Pro Val Leu Pro Ile
                 650                 655                 660

 Leu Ser Ile Phe Val Asn Val Tyr Leu Met Met Gln Leu Asp Gln
                 665                 670                 675

 Gly Thr Trp Val Arg Phe Ala Val Trp Met Leu Ile Gly Phe Ile
                 680                 685                 690

 Ile Tyr Phe Gly Tyr Gly Leu Trp His Ser Glu Glu Ala Ser Leu
                 695                 700                 705

 Asp Ala Asp Gln Ala Arg Thr Pro Asp Gly Asn Leu Asp Gln Cys
                 710                 715                 720

 Lys


<210> 2540
<211> 3141
<212> DNA
<213> Homo sapien

<400> 2540
 gcctgaaaac atcatgctgg ttgatccagt tcgccagccc taccgagtga 50

 aggtcattga ctttggttct gctagtcacg tttccaaagc tgtgtgctca 100

 acctacttac agtcacgtta ctacagagct cctgaaatta ttcttgggtt 150

 accattttgt gaagctattg atatgtggtc actgggctgt gtgatagctg 200

 agctgttcct gggatggcct ctttatcctg gtgcttcaga atatgatcag 250

 attcgttata tttcacaaac acaaggcttg ccagctgaat atcttctcag 300

 tgccggaaca aaaacaacca ggtttttcaa cagagatcct aatttggggt 350

 acccactgtg gaggcttaag acacctgaag aacatgaact ggagactgga 400

 ataaaatcaa aagaagctcg gaagtacatt tttaattgct tagatgacat 450

 ggctcaggtg aatatgtcta cagacctgga gggaacagac atgttggcag 500

 agaaggcaga ccgaagagaa tacattgatc tgttaaagaa aatgctcaca 550

 attgatgcag ataagagaat tacccctcta aaaactctta accatcagtt 600

 tgtgacaatg actcaccttt tggattttcc acatagcaat catgttaagt 650

 cttgttttca gaacatggag atctgcaagc ggagggttca catgtatgat 700

 acagtgagtc agatcaagag tcccttcact acacatgttg ccccaaatac 750

 aagcacaaat ctaaccatga gcttcagcaa tcagctcaat acagtgcaca 800

 atcaggccag tgttctagct tccagttcta ctgcagcagc tgctactctt 850

 tctctggcta attcagatgt ctcactacta aactaccagt cagctttgta 900

 cccatcatct gctgcaccag ttcctggagt tgcccagcag ggtgtttcct 950

 tgcagcctgg aaccacccag atttgcactc agacagatcc attccaacag 1000

 acatttatag tatgtccacc tgcgtttcaa actggactac aagcaacaac 1050

 aaagcattct ggattccctg tgaggatgga taatgctgta ccaattgtac 1100

 cccaggcacc agctgctcag ccactacaga ttcagtcagg agttctcacg 1150

 cagggaagct gtacaccact aatggtagca actctccacc ctcaagtagc 1200

 caccatcaca ccgcagtatg cggtgccctt tactctgagc tgcgcagccg 1250

 gccggccggc gctggttgaa cagactgccg ctgtactgca ggcgtggcct 1300

 ggagggactc agcaaattct cctgccttca acttggcaac agttgcctgg 1350

 ggtagctcta cacaactctg tccagcccac agcaatgatt ccagaggcca 1400

 tggggagtgg acagcagcta gctgactgga ggaatgccca ctcttatggc 1450

 aaccagtaca gcactatcat gcagcagcca tccttgctga ctaaccatgt 1500

 gacattggcc actgctcagc ctctgaatgt tggtgttgcc catgttgtca 1550

 gacaacaaca atccagttcc ctcccttcga agaagaataa gcagtcagct 1600

 ccagtctctt ccaagtcctc tctagatgtt ctgccttccc aagtctattc 1650

 tctggttggg agcagtcccc tccgcaccac atcttcttat aattccttgg 1700

 tccctgtcca agatcagcat cagcccatca tcattccaga tactcccagc 1750

 cctcctgtga gtgtcatcac tatccgaagt gacactgatg aggaagagga 1800

 caacaaatac aagcccagta gctctggact gaagccaagg tctaatgtca 1850

 tcagttatgt cactgtcaat gattctccag actctgactc ttctttgagc 1900

 agcccttatt ccactgatac cctgagtgct ctccgaggca atagtggatc 1950

 cgttttggag gggcctggca gagttgtggc agatggcact ggcacccgca 2000

 ctatcattgt gcctccactg aaaactcagc ttggtgactg cactgtagca 2050

 acccaggcct caggtctcct gagcaataag actaagccag tcgcttcagt 2100

 gagtgggcag tcatctggat gctgtatcac ccccacaggg tatcgagctc 2150

 aacgcggggg gaccagtgca gcacaaccac tcaatcttag ccagaaccag 2200

 cagtcatcgg cggctccaac ctcacaggag agaagcagca acccagcccc 2250

 ccgcaggcag caggcgtttg tggcccctct ctcccaagcc ccctacacct 2300

 tccagcatgg cagcccgcta cactcgacag ggcacccaca ccttgccccg 2350

 gcccctgctc acctgccaag ccaggctcat ctgtatacgt atgctgcccc 2400

 gacttctgct gctgcactgg gctcaaccag ctccattgct catcttttct 2450

 ccccacaggg ttcctcaagg catgctgcag cctataccac tcaccctagc 2500

 actttggtgc accaggtccc tgtcagtgtt gggcccagcc tcctcacttc 2550

 tgccagcgtg gcccctgctc agtaccaaca ccagtttgcc acccaatcct 2600

 acattgggtc ttcccgaggc tcaacaattt acactggata cccgctgagt 2650

 cctaccaaga tcagccagta ttcctactta tagttggtga gcatgaggga 2700

 ggaggaatca tggctacctt ctcctggccc tgcgttctta atattgggct 2750

 atggagagat cctcctttac cctcttgaaa tttcttagcc agcaacttgt 2800

 tctgcagggg cccactgaag cagaaggttt ttctctgggg gaacctgtct 2850

 cagtgttgac tgcattgttg tagtcttctc aaagtttgcc ctatttttaa 2900

 attcattatt tttgtgacag taattttggt acttggaaga gttcagatgc 2950

 ccatcttctg cagttaccaa ggaagagaga ttgttctgaa gttaccctct 3000

 gaaaaatatt ttgtctctct gacttgattt ctataaatgc ttttaaaaac 3050

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 3141

<210> 2541
<211> 2190
<212> DNA
<213> Homo sapien

<400> 2541
 ggcttacagg agggcagctc tgcagttggg aggggcaccg tccggaggag 50

 accaggcctc tacacacccc ccactctact tatcatccct gctcacacac 100

 ccttgtccaa ggctttatgc atcggattta tttttccaaa tcaagaggac 150

 agtgatagat gcattttccc caggctgtct cagaaaggtc gctaaatgta 200

 tactgttgtc agaattgctg agatctcccc ccacttttgg tttttgcagc 250

 agtaaaaact ctttccactg tgacttattt tctctctcag gcagccagcc 300

 acctggtccc ttgtgctgac tctagcacag tggccaggat ccaatacgag 350

 tccaggggtg accgcaggat ggtgggggca gcgggcttct ccacctaccc 400

 cagccaccaa ggccctgacg cactgcctcc tgcaccttca gcacatccct 450

 gtgcacagct ggaagggtgc atggcccgct cacctttgtt cagatgggtg 500

 gaaacgctga tgataccagc tcctccctgc cgtgcccctg ccacggagca 550

 ggcattgtga actggctggt gtttgcagtc ccacgtggca tggcctccag 600

 cccaacccac agtggagact ggagacaggg caatgagtct ggtcgggggc 650

 acgtggacat gccccatagg ggccccaccc agacttaaca ggcaaggtcc 700

 tgggcattgc gcgacgcagg actcaatgct aaagcaagcc tgcctggctc 750

 tgtgccaggg cccctcttct gatttacaca tcccattttt acacagaccc 800

 ttccttctta ataaaggctg acagttctgt tggcagccaa gaacccacac 850

 catgaagaca gggagtgagg ggcctttgtg cccaactcca gcacagctgc 900

 gttctggggt gtgtgagagg catgttcgtg tctgtgcgct ggtggtctcg 950

 tgagacagtt ccgaggacgg ggaaattgca gggtggtggg ggcgtgaggc 1000

 ttatatgtgg aactgatgca gagttcgcct gcagacggat ctggatatac 1050

 actatgtata attgttacgt gtaatttaaa atatatctgt ttgccatcgt 1100

 catgagaaga ttatatgtaa ggctctgaag ggagagggag atgtacattc 1150

 tgccaggctc ctggggacct tatccgagtc atgaaattga tgactgttga 1200

 tccagtggtg caagaagcta cactccatgt gtcatcacgc ttatgactcc 1250

 taatgtattt ttaaggcaaa aaatgtcagc cgactccatc ttcacccctc 1300

 gattcctcga gtccagcctt tctgtgccag tgcttcactg agccacaacg 1350

 ctctcgccat cgggacccgg ctgggcctgg agtctcgggg cacagttgcc 1400

 atggagccct cctgggtcat tctacaaatg tgctgagtgc cagctgaaaa 1450

 ccccacagga gatggagtac cttggccaag cttaaagaga agattttctc 1500

 agggtattta ttagtgtgtc cagcagggtc aggaagcagg atggaaagat 1550

 gcattcagac tgttaattta ttaacaaggc aaatgatttt gtgtttcttg 1600

 atgacagact attaagtttg ggacttattt tcccatttga gaagttataa 1650

 tatatattta agatgataag tttcctgctt aagttgtgcc tttcagcttc 1700

 aatgagttta aggagcacta agggtaatga taccaatgag ggttggttta 1750

 ttatcaaacc tgaatagctg tggtttctcc agtaaatatt ttcttctact 1800

 gaacatggag ccattattaa gagttgtgtg ttttttatta tgtacatttg 1850

 tatatttttt tgcttgtttg atgttctatt tttctaatag ttttctttta 1900

 gtttcttaaa gttgtgatac tagatttaga ttctgatgct aactgcaaat 1950

 caggttggtc tctgctgggt ctctcctgct tttattttac tttaaggaca 2000

 agtgtagttg tcgtccacca cctttcaaaa aatgtgaaac tgccctgcct 2050

 cccctttttg ctgacaacac tgtgtacatt gaccacttcc taccatactt 2100

 tatgttgtaa aatcaaactc ttttgtggta cattatctca tgcttctgca 2150

 aattcgaata aattctatgg cttccaaaaa aaaaaaaaaa 2190

<210> 2542
<211> 21
<212> PRT
<213> Homo sapien

<400> 2542
 Met Lys Leu Met Thr Val Asp Pro Val Val Gln Glu Ala Thr Leu
   1               5                  10                  15

 His Val Ser Ser Arg Leu
                  20

<210> 2543
<211> 5186
<212> DNA
<213> Homo sapien

<400> 2543
 ggctgcgtca tttttgaact gcttacctta aagaggacgt ttgatgctac 50

 aaacccactt aacctgtgtg tgaagatcgt gcaaggaatt cgggccatgg 100

 aagttgactc tagccagtac tctttggaat tgatccaaat ggttcattcg 150

 tgccttgacc aggatcctga gcagagacct actgcagatg aacttctaga 200

 tcgccctctt ctcaggaaac gcaggagaga gatggaggaa aaagtcactc 250

 tgcttaatgc acctacaaag agaccaaggt caagcactgt gactgaagca 300

 cccattgctg tagtaacatc acgaaccagt gaagtctatg tttggggtgg 350

 tggaaaatcc accccccaga aactggatgt tatcaagagt ggctgtagtg 400

 cccggcaggt ctgtgcaggg aatacccact ttgctgtggt cacagtggag 450

 aaggaactgt acacttgggt gaacatgcaa ggaggcacta aactccatgg 500

 tcagctgggc catggagaca aagcctccta tcgacagcca aagcatgtgg 550

 aaaagttgca aggcaaagct atccatcagg tgtcatgtgg tgatgatttc 600

 actgtctgtg tgactgatga gggtcagctc tatgccttcg gatcagatta 650

 ttatggctgc atgggggtgg acaaagttgc tggccctgaa gtgctagaac 700

 ccatgcagct gaacttcttc ctcagcaatc cagtggagca ggtctcctgt 750

 ggagataatc atgtggtggt tctgacacga aacaaggaag tctattcttg 800

 gggctgtggc gaatatggta ggggtagcct tgtctctgtc cacttcttca 850

 caggtataca acctgacttc aaagttgtat gcatctaaac ccatcatgca 900

 gcccctaaat gagaagtgtt aattcagtaa atcttttttt tttttttttt 950

 ttttttttct cgagacagag tctctctctg tcacccaggc tggagtgcaa 1000

 tggcatgatc tgggctcatt gcaaccacca cctcccgagt tcgagtgatt 1050

 ctcctgcctc agcctcccga gtagctggga ttacaggcac acaccatcac 1100

 acccagctaa ttttttgtat ttttagtaga gatggggttt caccacactg 1150

 gccaggcttg tctcgctcga acttctgacc tcatgatcca cctgcctcgg 1200

 cctcccaaag tgctgggatt acaggtgtga gccaccgcac ctggcaaaag 1250

 agaatcttac agaacctatt cactgggaag gaagccctca ttataatgat 1300

 tttcattctt atgtgtgttt caggacgact gggtttggat tcagaagagg 1350

 attattatac accacaaaag gtggatgttc ccaaggcctc gattattgtt 1400

 gcagttcaat gtggctgtga tgggacattt ctgttgaccc agtcaggcaa 1450

 agtgctggcc tgtggactca atgaattcaa taagctgggt ctgaatcagt 1500

 gcatgtcggg aattatcaac catgaagcat accatgaagt tccctacaca 1550

 acgtccttta ccttggccaa acagttgtcc ttttataaga tccgtaccat 1600

 tgccccaggc aagactcaca cagctgctat tgatgagcga ggccggctgc 1650

 tgacctttgg ctgcaacaag tgtgggcagc tgggcgttgg gaactacaag 1700

 aagcgtctgg gaatcaacct gttgggggga cccttggtgg gaagcaagtg 1750

 atcagggtct cctgcggtga tgagtttacc attgctgcca ctgatgataa 1800

 tcacattttt gcctggggca atggtggtaa tggccgcctg gcaatgaccc 1850

 ccacagagag accacatggc tctgatatct gtacctcatg gcctcggcct 1900

 atttttggat ctctgcatca tgtcccggac ctgtcttgcc gtggatggca 1950

 taccattctc atcgttgaga aagtattgaa ttctaagacc atccgttcca 2000

 atagcagtgg cttatccatt ggaactgtgt ttcagagctc tagcccggga 2050

 ggaggcggcg ggggcggcgg tggtgaagaa gaggacagtc agcaggaatc 2100

 tggaactcct gacccaagtg gaggcttccg aggaacaatg gaagcagacc 2150

 gaggaatgga aggtttaatc agtcccacag aggccatggg gaacagtaat 2200

 ggggccagca gctcctgtcc tggctggctt cgaaaggagc tggaaaatgc 2250

 agaatttatc cccatgcctg acagcccatc tcctctcagt gcagcgtttt 2300

 cagaatctga gaaagatacc ctgccctatg aagagctgca aggactcaaa 2350

 gtggcctctg aagctccttt ggaacacaaa ccccaagtag aagcctcgtc 2400

 acctcggctg aatcctgcag taacctgtgc tgggaaggga acaccactga 2450

 ctcctcctgc gtgtgcgtgc agctctctgc aggtggaggt tgagagattg 2500

 cagggtctgg tgttaaagtg tctggctgaa caacagaagc tacagcaaga 2550

 aaacctccag atttttaccc aactgcagaa gttgaacaag aaattagaag 2600

 gagggcagca ggtggggatg cattccaaag gaactcagac agcaaaggaa 2650

 gagatggaaa tggatccaaa gcctgactta gattcagatt cctggtgcct 2700

 cctgggaaca gactcctgta gacccagcct ctagtctcct gagcctatag 2750

 agcccccagg agactgggac ccaaagaact tcacagcaca cttaccgaat 2800

 gcagagagca gctttcctgg ctttgttcac ttgcagaaaa ggagcgcaag 2850

 gcagaggctc tgaagcactt tccttgtaca tttggagagt ggcattgcct 2900

 tttagatagg atctaggagt gattttattg ttttggagaa tggaagggcc 2950

 cccatggccc tggctttgtc atcagtgact gccatagcaa cagcagctct 3000

 gtacctcatc tgttgatccc acctttgaag aggagacaca gtgctcacct 3050

 taattgcgct ggtagcagct tatatcccat gtatcatttt caccattgat 3100

 tggaagctgc cttgggaatt cagtaccagg cattacccct ctgggtggga 3150

 gagggagaag tgtaaagttg gagtgggctg gaatcaggtg tggcccgccc 3200

 agtgtcctct gcagagtggt gaagtagtct ggccctcttg ggagccctga 3250

 gtccaggaaa atatgtctga tggagtcaat ctagggcttg tttcgaaaaa 3300

 gttcagttac tctgtgcagc taaatgcttt aggaggaaag gtaggcttag 3350

 gttgcttttc ctctgagggt tgattgaaat ttcttcagtg aggaatagag 3400

 aaagggcagg accctcatca tcacacagct ggtgtttcag gctgtgacca 3450

 atgcagggtg ggatttccta actgtggatg aggggatgag gtgtctctga 3500

 gggatgaggt gtctcagaga attgagtcca tggggcagtc agaatagcct 3550

 taagagaaaa tcatgaagga gaagaggtcc tcctttagct gcctctactt 3600

 ggtatcttag agagggctta gagggctctc agtcttctgc ccatgaaaag 3650

 acttctttga gcctctgcct tcatggctct tagggttctg atcttgatat 3700

 cagcggcccc aaccactttc tttctgaatg tctagtcagt atttttcccc 3750

 ttttggtgtt ttatgaagcc atgtggtaac gaatgaatct gtatcatttt 3800

 tcctacctga gtggcccaaa gccagcacca aaccctggga gtccctgaag 3850

 cctaacagaa caggtagaac ttgcaaaagg aatttggctg agagctcact 3900

 tctaatcctg tactcactgt gtctttgtag atagaaacaa gctagcttta 3950

 ccaaagagaa atagtgtcat agaagaacaa aacttcatat agaaagttct 4000

 aggcaagtat ttgatggttt ccttaaggat gtgagctttg tatttccacc 4050

 tagccttgta aaatgttcct gtggtatttt gtgtcacaca tcctaccttt 4100

 gatgagtctc acatcccacc ttcctataaa cagctaaatt aattttgttt 4150

 catcttcccc agaccaaaat gtttgataat cttatcaaca ttgtgggagg 4200

 tcttgtgcaa tggaaatttt gccatttctc caaaactggt ggcataaagg 4250

 ctaatgcttg gggagaaccc cattgctcgg gacaggcaac tctgttcaat 4300

 gggatcttct ttggtttgat ggtcccattg ttttctcagt tctgggaagc 4350

 ctagtacatt agtactaatg taatcactga aaccttttct tgaaataagg 4400

 gaagcagcca aactttgatt aaagttgcaa gttctgggga cttgcggggg 4450

 ttgtcataaa ctgtaacagt gggttttggt tcagcatgta aatgcaactt 4500

 tgattttctt gaggaccgat tgacctgtca tgtccctgta tcctcatgct 4550

 catcatctca gcaggcctga gaggctgggt cagtttgggt gttcatcatg 4600

 aggattgctt ctgccatgga gctgatggac gtgggcaggt tgctgagaag 4650

 gtggggtgaa agtgagtgcc gggggtgggt gagtgccctg gtcttgttca 4700

 taggggagcc tttccctagc agtggaacgc tgtggtcatt ttctctagca 4750

 tattcccttg ggaagtctag atttgctatt aatctggctg agaatctaag 4800

 ttctgtgcct tagagacagt ttgcactttc ccatattgtg cctgggacag 4850

 ccatatgatt ttttttccca ccaaacaagt atgcaaacag aaaccagttc 4900

 aaagggggat ggagtaaaag atgaggcagt agaaatgcct ttgaatggtt 4950

 ttctgtagct aattctcttt aaattttgtc ctgctttttt tctttatgca 5000

 gtgctaggtg ttttaagttt tctagtagta ttgcttttga gttacagtat 5050

 aacctgagtt actcctctgc tctaacattg ttgcagaaga actagtttat 5100

 tgttagccag gttgcttgaa aggttgagag tggagtggtt tggcatttct 5150

 gttttaaata aacatttaag ctcttaagaa aaaaaa 5186

<210> 2544
<211> 295
<212> PRT
<213> Homo sapien

<400> 2544
 Gly Cys Val Ile Phe Glu Leu Leu Thr Leu Lys Arg Thr Phe Asp
   1               5                  10                  15

 Ala Thr Asn Pro Leu Asn Leu Cys Val Lys Ile Val Gln Gly Ile
                  20                  25                  30

 Arg Ala Met Glu Val Asp Ser Ser Gln Tyr Ser Leu Glu Leu Ile
                  35                  40                  45

 Gln Met Val His Ser Cys Leu Asp Gln Asp Pro Glu Gln Arg Pro
                  50                  55                  60

 Thr Ala Asp Glu Leu Leu Asp Arg Pro Leu Leu Arg Lys Arg Arg
                  65                  70                  75

 Arg Glu Met Glu Glu Lys Val Thr Leu Leu Asn Ala Pro Thr Lys
                  80                  85                  90

 Arg Pro Arg Ser Ser Thr Val Thr Glu Ala Pro Ile Ala Val Val
                  95                 100                 105

 Thr Ser Arg Thr Ser Glu Val Tyr Val Trp Gly Gly Gly Lys Ser
                 110                 115                 120

 Thr Pro Gln Lys Leu Asp Val Ile Lys Ser Gly Cys Ser Ala Arg
                 125                 130                 135

 Gln Val Cys Ala Gly Asn Thr His Phe Ala Val Val Thr Val Glu
                 140                 145                 150

 Lys Glu Leu Tyr Thr Trp Val Asn Met Gln Gly Gly Thr Lys Leu
                 155                 160                 165

 His Gly Gln Leu Gly His Gly Asp Lys Ala Ser Tyr Arg Gln Pro
                 170                 175                 180

 Lys His Val Glu Lys Leu Gln Gly Lys Ala Ile His Gln Val Ser
                 185                 190                 195

 Cys Gly Asp Asp Phe Thr Val Cys Val Thr Asp Glu Gly Gln Leu
                 200                 205                 210

 Tyr Ala Phe Gly Ser Asp Tyr Tyr Gly Cys Met Gly Val Asp Lys
                 215                 220                 225

 Val Ala Gly Pro Glu Val Leu Glu Pro Met Gln Leu Asn Phe Phe
                 230                 235                 240

 Leu Ser Asn Pro Val Glu Gln Val Ser Cys Gly Asp Asn His Val
                 245                 250                 255

 Val Val Leu Thr Arg Asn Lys Glu Val Tyr Ser Trp Gly Cys Gly
                 260                 265                 270

 Glu Tyr Gly Arg Gly Ser Leu Val Ser Val His Phe Phe Thr Gly
                 275                 280                 285

 Ile Gln Pro Asp Phe Lys Val Val Cys Ile
                 290                 295

<210> 2545
<211> 4355
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4185, 4190
<223> Unknown base

<400> 2545
 gcagcagcag caaccccgcc gctcgcggtc ggccccgggc cgcagcatgg 50

 tcccgagtgg cggagtcccc cagggcctcg gcggccgctc tgcctgcgcg 100

 ctgctcctgc tctgctacct gaatgttgta ccatctttgg gtaggcagac 150

 ttccctgacg acatcagtga tacccaaagc tgagcagagc gtggcttaca 200

 aagactttat ttattttact gtctttgaag gaaacgttcg caacgtttct 250

 gaagtctcgg ttgagtattt atgctctcag ccttgtgttg tcaatttgga 300

 agcagttgtt tcatctgagt tcagaagtag cattcccgtg tacaaaaaaa 350

 ggtggaagaa tgagaaacat cttcacacca gcaggacaca aatagtacat 400

 gtgaaatttc caagcattat ggtttacaga gatgattatt tcatcagaca 450

 ttccatctct gtatctgcag tgatagtacg cgcctggatt actcacaaat 500

 acagtggcag agactggaat gttaaatggg aggaaaactt gctccatgct 550

 gtagcaaaga attataccct cctgcagacc atcccgcctt ttgaacgccc 600

 tttcaaagat catcaagtgt gccttgagtg gaacatgggt tatatttgga 650

 accttcgggc aaacaggatt ccacagtgtc ctctggaaaa tgatgtggtt 700

 gccctgcttg gctttcctta tgcctccagt ggagaaaaca caggcattgt 750

 caagaagttc ccgaggtttc ggaaccgaga gctggaggcc actcgacgcc 800

 agaggatgga ttacccagtg tttactgttt cattgtggct ttatttactc 850

 cattattgca aggccaacct ctgtgggatt ctgtactttg ttgactctaa 900

 tgagatgtac ggcacacctt ctgtatttct tacggaagag ggctatttgc 950

 atattcagat gcatcttgtc aaaggggaag accttgctgt aaaaactaaa 1000

 ttcatcatac ctttgaagga gtggtttcga ctggatatct cttttaacgg 1050

 aggccagata gtagtaacca ctagcattgg acaggatttg aaaagctacc 1100

 acaatcagac cattagcttc cgggaggatt tccattataa tgacacagct 1150

 gggtacttca ttattggagg gagcaggtat gtggctggca ttgaagggtt 1200

 ttttggaccc ctgaagtact atcgccttcg cagtctgcac cccgcccaga 1250

 tttttaatcc cctccttgag aagcaacttg ctgaacaaat caagttatat 1300

 tatgaaaggt gtgctgaggt tcaagaaata gtatctgtgt atgcatctgc 1350

 agcaaagcac gggggcgaga gacaagaagc atgccacctc cacaactcct 1400

 acctggacct ccagcgcagg tatgggagac cctcgatgtg cagagccttc 1450

 ccctgggaga aggagctgaa agacaaacac cccagcttgt tccaggcatt 1500

 gctggagatg gatctgctga ccgtgccaag gaaccaaaat gaatctgtat 1550

 cagaaatcgg tgggaagata tttgagaagg ctgtaaagag actctctagc 1600

 attgatggtc ttcaccaaat tagctctatc gtcccctttc tgacggattc 1650

 cagctgctgt ggataccata aagcatccta ctaccttgca gtcttttatg 1700

 agactggatt aaatgttcct cgggatcagc tgcagggcat gttgtatagt 1750

 ttggttggag gccaggggag tgagaggctg tcttcaatga atcttgggta 1800

 taaacactac cagggtattg acaactaccc cctggactgg gaactgtcgt 1850

 atgcctacta cagcaacatt gccaccaaga caccccttga ccagcacaca 1900

 ctgcaaggag atcaggcata tgttgaaaca attagactaa aagatgatga 1950

 aatactcaag gtacaaacca aagaagatgg agatgtcttt atgtggttga 2000

 agcatgaagc tacccgaggc aatgcagcag ctcagcaacg attggcccag 2050

 atgctgttct gggggcagca aggtgtggcc aagaatcccg aagcagcaat 2100

 tgagtggtac gccaagggcg ccctggagac ggaggatcct gcgttaatct 2150

 atgactatgc cattgtgcta ttcaagggtc aaggagtaaa aaagaacaga 2200

 cggcttgcct tagagctgat gaagaaagca gcttccaagg gattgcatca 2250

 ggcagtcaat ggcctgggat ggtattacca caaattcaag aaaaattacg 2300

 ccaaagcagc aaagtactgg ttaaaagcag aagaaatggg gaacccagat 2350

 gcgtcataca atcttggagt cctgcatttg gatggcatct tccctggagt 2400

 tcctggaagg aatcaaactt tagctggtga atatttccat aaggctgcgc 2450

 aaggtggaca catggaaggg accttgtggt gttctctcta ctatatcaca 2500

 ggcaacctgg agacattccc tagagatcct gagaaagctg ttgtatgggc 2550

 aaaacatgta gctgagaaaa atggctactt gggccatgtc atccgcaaag 2600

 gcctcaatgc ctacctggaa ggttcatggc atgaagcttt gctgtattat 2650

 gttttagcag cagaaactgg aattgaagtg tcacagacaa atttagcaca 2700

 catctgtgag gagaggccag acctggccag gagatacttg ggtgttaact 2750

 gtgtttggag atactataat ttctctgttt ttcaaatcga tgctccttcc 2800

 tttgcatatt tgaagatggg agacctttac tactatggcc accaaaacca 2850

 gtcacaagac ctggagttgt ctgtgcagat gtacgcccaa gccgccctgg 2900

 atggagactc ccagggattt tttaacctgg ccctgctaat cgaggaaggt 2950

 acgataatcc cacaccatat cttggatttc ttggaaattg actcaactct 3000

 ccattctaat aacatctcca ttctccagga actgtacgaa aggtgctgga 3050

 gccacagtaa cgaggagtcc ttcagcccct gctccttggc ctggctttac 3100

 ctgcacttgc ggcttctctg gggtgctatc ctgcactcag ccctgatcta 3150

 ctttctggga acctttctgc tatccatatt gatcgcctgg actgtgcagt 3200

 atttccagtc tgtctcagca agcgatcccc ctccaagacc atcccaggcc 3250

 tccccagaca ctgccacgtc cactgcaagt ccagctgtga ctccagctgc 3300

 agatgcctct gaccaagacc agcccacagt aactaataac ccggagccac 3350

 gtgggtgaac tgtgcactcc agttctctcc agatgagaga gaatcttttc 3400

 aacagctggt attgggaagc tggggccagg gcatgatcct gataaacacc 3450

 ttaaatgtct tgtcaactgg atgcaaattt tgcaattggt gtcatttttt 3500

 ttaaagtcaa attacaagga agtacccaga tcaggcagtg gtaataccaa 3550

 aggtcatcaa acacatacaa ggaacatctt gatcataggg catgtgggga 3600

 agtttactgg gccatcacag acttttgttc tagtgattgt atgtattagg 3650

 agtcatagca tgccctacgg cagatctgga ttcttataca ctaagatgtg 3700

 tcttaagaat cacagtgcgt gcttcatccc tttattgaag aacagaaaat 3750

 tatgactact ctacaaggtg gataatattt tggtacctgt gcttgccaca 3800

 gccctgttcc tcaaagctga attgatagat ttctctttga cttccaagac 3850

 ctagcagtta taaggcacct tgaaataaat tgtttgtgcc tggaaatgca 3900

 gggagggcaa tagctttgta aattggttta catttttctc cttgaatttt 3950

 tctagggtcc tagtgcttcc gaatcattta atggcattgt cggatatctt 4000

 ttacatttca attgcaatcc atgaaattac atttagaaga ttcttagtac 4050

 ttaactgtag tcttctccat gaattacacg ttagaataga ctggcagcaa 4100

 ctgaatatgc agcaagtaag cctctagctt atagtttcat ccctacccct 4150

 catgcctgcg tgagtctgta cagggatatt gtgtntgtgn gtgtgtgtgt 4200

 gtgtttagag aggaagagga agagcagaat gtctgtatac tacatgctgc 4250

 taaggtagtg aataaatcag taatgcaata ttgtgggtcc aaactactct 4300

 ttgcactact ttatttacag tagtaaataa aattattttt atacaattga 4350

 ctacc 4355

<210> 2546
<211> 1118
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4185, 4190
<223> Unknown amino acid

<400> 2546
 Gln Gln Gln Gln Pro Arg Arg Ser Arg Ser Ala Pro Gly Arg Ser
   1               5                  10                  15

 Met Val Pro Ser Gly Gly Val Pro Gln Gly Leu Gly Gly Arg Ser
                  20                  25                  30

 Ala Cys Ala Leu Leu Leu Leu Cys Tyr Leu Asn Val Val Pro Ser
                  35                  40                  45

 Leu Gly Arg Gln Thr Ser Leu Thr Thr Ser Val Ile Pro Lys Ala
                  50                  55                  60

 Glu Gln Ser Val Ala Tyr Lys Asp Phe Ile Tyr Phe Thr Val Phe
                  65                  70                  75

 Glu Gly Asn Val Arg Asn Val Ser Glu Val Ser Val Glu Tyr Leu
                  80                  85                  90

 Cys Ser Gln Pro Cys Val Val Asn Leu Glu Ala Val Val Ser Ser
                  95                 100                 105

 Glu Phe Arg Ser Ser Ile Pro Val Tyr Lys Lys Arg Trp Lys Asn
                 110                 115                 120

 Glu Lys His Leu His Thr Ser Arg Thr Gln Ile Val His Val Lys
                 125                 130                 135

 Phe Pro Ser Ile Met Val Tyr Arg Asp Asp Tyr Phe Ile Arg His
                 140                 145                 150

 Ser Ile Ser Val Ser Ala Val Ile Val Arg Ala Trp Ile Thr His
                 155                 160                 165

 Lys Tyr Ser Gly Arg Asp Trp Asn Val Lys Trp Glu Glu Asn Leu
                 170                 175                 180

 Leu His Ala Val Ala Lys Asn Tyr Thr Leu Leu Gln Thr Ile Pro
                 185                 190                 195

 Pro Phe Glu Arg Pro Phe Lys Asp His Gln Val Cys Leu Glu Trp
                 200                 205                 210

 Asn Met Gly Tyr Ile Trp Asn Leu Arg Ala Asn Arg Ile Pro Gln
                 215                 220                 225

 Cys Pro Leu Glu Asn Asp Val Val Ala Leu Leu Gly Phe Pro Tyr
                 230                 235                 240

 Ala Ser Ser Gly Glu Asn Thr Gly Ile Val Lys Lys Phe Pro Arg
                 245                 250                 255

 Phe Arg Asn Arg Glu Leu Glu Ala Thr Arg Arg Gln Arg Met Asp
                 260                 265                 270

 Tyr Pro Val Phe Thr Val Ser Leu Trp Leu Tyr Leu Leu His Tyr
                 275                 280                 285

 Cys Lys Ala Asn Leu Cys Gly Ile Leu Tyr Phe Val Asp Ser Asn
                 290                 295                 300

 Glu Met Tyr Gly Thr Pro Ser Val Phe Leu Thr Glu Glu Gly Tyr
                 305                 310                 315

 Leu His Ile Gln Met His Leu Val Lys Gly Glu Asp Leu Ala Val
                 320                 325                 330

 Lys Thr Lys Phe Ile Ile Pro Leu Lys Glu Trp Phe Arg Leu Asp
                 335                 340                 345

 Ile Ser Phe Asn Gly Gly Gln Ile Val Val Thr Thr Ser Ile Gly
                 350                 355                 360

 Gln Asp Leu Lys Ser Tyr His Asn Gln Thr Ile Ser Phe Arg Glu
                 365                 370                 375

 Asp Phe His Tyr Asn Asp Thr Ala Gly Tyr Phe Ile Ile Gly Gly
                 380                 385                 390

 Ser Arg Tyr Val Ala Gly Ile Glu Gly Phe Phe Gly Pro Leu Lys
                 395                 400                 405

 Tyr Tyr Arg Leu Arg Ser Leu His Pro Ala Gln Ile Phe Asn Pro
                 410                 415                 420

 Leu Leu Glu Lys Gln Leu Ala Glu Gln Ile Lys Leu Tyr Tyr Glu
                 425                 430                 435

 Arg Cys Ala Glu Val Gln Glu Ile Val Ser Val Tyr Ala Ser Ala
                 440                 445                 450

 Ala Lys His Gly Gly Glu Arg Gln Glu Ala Cys His Leu His Asn
                 455                 460                 465

 Ser Tyr Leu Asp Leu Gln Arg Arg Tyr Gly Arg Pro Ser Met Cys
                 470                 475                 480

 Arg Ala Phe Pro Trp Glu Lys Glu Leu Lys Asp Lys His Pro Ser
                 485                 490                 495

 Leu Phe Gln Ala Leu Leu Glu Met Asp Leu Leu Thr Val Pro Arg
                 500                 505                 510

 Asn Gln Asn Glu Ser Val Ser Glu Ile Gly Gly Lys Ile Phe Glu
                 515                 520                 525

 Lys Ala Val Lys Arg Leu Ser Ser Ile Asp Gly Leu His Gln Ile
                 530                 535                 540

 Ser Ser Ile Val Pro Phe Leu Thr Asp Ser Ser Cys Cys Gly Tyr
                 545                 550                 555

 His Lys Ala Ser Tyr Tyr Leu Ala Val Phe Tyr Glu Thr Gly Leu
                 560                 565                 570

 Asn Val Pro Arg Asp Gln Leu Gln Gly Met Leu Tyr Ser Leu Val
                 575                 580                 585

 Gly Gly Gln Gly Ser Glu Arg Leu Ser Ser Met Asn Leu Gly Tyr
                 590                 595                 600

 Lys His Tyr Gln Gly Ile Asp Asn Tyr Pro Leu Asp Trp Glu Leu
                 605                 610                 615

 Ser Tyr Ala Tyr Tyr Ser Asn Ile Ala Thr Lys Thr Pro Leu Asp
                 620                 625                 630

 Gln His Thr Leu Gln Gly Asp Gln Ala Tyr Val Glu Thr Ile Arg
                 635                 640                 645

 Leu Lys Asp Asp Glu Ile Leu Lys Val Gln Thr Lys Glu Asp Gly
                 650                 655                 660

 Asp Val Phe Met Trp Leu Lys His Glu Ala Thr Arg Gly Asn Ala
                 665                 670                 675

 Ala Ala Gln Gln Arg Leu Ala Gln Met Leu Phe Trp Gly Gln Gln
                 680                 685                 690

 Gly Val Ala Lys Asn Pro Glu Ala Ala Ile Glu Trp Tyr Ala Lys
                 695                 700                 705

 Gly Ala Leu Glu Thr Glu Asp Pro Ala Leu Ile Tyr Asp Tyr Ala
                 710                 715                 720

 Ile Val Leu Phe Lys Gly Gln Gly Val Lys Lys Asn Arg Arg Leu
                 725                 730                 735

 Ala Leu Glu Leu Met Lys Lys Ala Ala Ser Lys Gly Leu His Gln
                 740                 745                 750

 Ala Val Asn Gly Leu Gly Trp Tyr Tyr His Lys Phe Lys Lys Asn
                 755                 760                 765

 Tyr Ala Lys Ala Ala Lys Tyr Trp Leu Lys Ala Glu Glu Met Gly
                 770                 775                 780

 Asn Pro Asp Ala Ser Tyr Asn Leu Gly Val Leu His Leu Asp Gly
                 785                 790                 795

 Ile Phe Pro Gly Val Pro Gly Arg Asn Gln Thr Leu Ala Gly Glu
                 800                 805                 810

 Tyr Phe His Lys Ala Ala Gln Gly Gly His Met Glu Gly Thr Leu
                 815                 820                 825

 Trp Cys Ser Leu Tyr Tyr Ile Thr Gly Asn Leu Glu Thr Phe Pro
                 830                 835                 840

 Arg Asp Pro Glu Lys Ala Val Val Trp Ala Lys His Val Ala Glu
                 845                 850                 855

 Lys Asn Gly Tyr Leu Gly His Val Ile Arg Lys Gly Leu Asn Ala
                 860                 865                 870

 Tyr Leu Glu Gly Ser Trp His Glu Ala Leu Leu Tyr Tyr Val Leu
                 875                 880                 885

 Ala Ala Glu Thr Gly Ile Glu Val Ser Gln Thr Asn Leu Ala His
                 890                 895                 900

 Ile Cys Glu Glu Arg Pro Asp Leu Ala Arg Arg Tyr Leu Gly Val
                 905                 910                 915

 Asn Cys Val Trp Arg Tyr Tyr Asn Phe Ser Val Phe Gln Ile Asp
                 920                 925                 930

 Ala Pro Ser Phe Ala Tyr Leu Lys Met Gly Asp Leu Tyr Tyr Tyr
                 935                 940                 945

 Gly His Gln Asn Gln Ser Gln Asp Leu Glu Leu Ser Val Gln Met
                 950                 955                 960

 Tyr Ala Gln Ala Ala Leu Asp Gly Asp Ser Gln Gly Phe Phe Asn
                 965                 970                 975

 Leu Ala Leu Leu Ile Glu Glu Gly Thr Ile Ile Pro His His Ile
                 980                 985                 990

 Leu Asp Phe Leu Glu Ile Asp Ser Thr Leu His Ser Asn Asn Ile
                 995                1000                1005

 Ser Ile Leu Gln Glu Leu Tyr Glu Arg Cys Trp Ser His Ser Asn
                1010                1015                1020

 Glu Glu Ser Phe Ser Pro Cys Ser Leu Ala Trp Leu Tyr Leu His
                1025                1030                1035

 Leu Arg Leu Leu Trp Gly Ala Ile Leu His Ser Ala Leu Ile Tyr
                1040                1045                1050

 Phe Leu Gly Thr Phe Leu Leu Ser Ile Leu Ile Ala Trp Thr Val
                1055                1060                1065

 Gln Tyr Phe Gln Ser Val Ser Ala Ser Asp Pro Pro Pro Arg Pro
                1070                1075                1080

 Ser Gln Ala Ser Pro Asp Thr Ala Thr Ser Thr Ala Ser Pro Ala
                1085                1090                1095

 Val Thr Pro Ala Ala Asp Ala Ser Asp Gln Asp Gln Pro Thr Val
                1100                1105                1110

 Thr Asn Asn Pro Glu Pro Arg Gly
                1115

<210> 2547
<211> 4853
<212> DNA
<213> Homo sapien

<400> 2547
 ttcgccgttt gaattgctgc gggcccgggc cctcacctca cctgaggtcc 50

 ggccgcccag gggtgcgcta tgccgtcggg aggtgaccag tcgccaccgc 100

 ccccgcctcc ccctccggcg gcggcagcct cggatgagga ggaggaggac 150

 gacggcgagg cggaagacgc cgcgccgtct gccgagtcgc ccacccctca 200

 gatccagcag cggttcgacg agctgtgcag ccgcctcaac atggacgagg 250

 cggcgcggcc cgaggcctgg gacagctacc gcagcatgag cgaaagctac 300

 acgctggagg gaaatgatct tcattggtta gcatgtgcct tatatgtggc 350

 ttgcagaaaa tctgttccaa ctgtaagcaa agggacagtg gaaggaaact 400

 atgtatcttt aactagaatc ctgaaatgtt cagagcagag cttaatcgaa 450

 ttttttaata agatgaagaa gtgggaagac atggcaaatc tacccccaca 500

 tttcagagaa cgtactgaga gattagaaag aaacttcact gtttctgctg 550

 taatttttaa gaaatatgaa cccatttttc aggacatctt taaataccct 600

 caagaggagc aacctcgtca gcagcgagga aggaaacagc ggcgacagcc 650

 ctgtactgtg tctgaaattt tccatttttg ttgggtgctt tttatatatg 700

 caaaaggtaa tttccccatg attagtgatg atttggtcaa ttcttatcac 750

 ctgctgctgt gtgctttgga cttagtttat ggaaatgcac ttcagtgttc 800

 taatcgtaaa gaacttgtga accctaattt taaaggctta tctgaagatt 850

 ttcatgctaa agattctaaa ccttcctctg accccccttg tatcattgag 900

 aaactgtgtt ccttacatga tggcctagtt ttggaagcaa aggggataaa 950

 ggaacatttc tggaaaccct atattaggaa actttatgaa aaaaagctcc 1000

 ttaagggaaa agaagaaaat ctcactgggt ttctagaacc tgggaacttt 1050

 ggagagagtt ttaaagccat caataaggcc tatgaggagt atgttttatc 1100

 tgttgggaat ttagatgagc ggatatttct tggagaggat gctgaggagg 1150

 aaattgggac tctctcaagg tgtctgaacg ctggttcagg aacagagact 1200

 gctgaaaggg tgcagatgaa aaacatctta cagcagcatt ttgacaagtc 1250

 caaagcactt agaatctcca caccactaac tggtgttagg tacattaagg 1300

 agaatagccc ttgtgtgact ccagtttcta cagctacgca tagcttgagt 1350

 cgtcttcaca ccatgctgac aggcctcagg aatgcaccaa gtgagaaact 1400

 ggaacagatt ctcaggacat gttccagaga tccaacccag gctattgcta 1450

 acagactgaa agaaatgttt gaaatatatt ctcagcattt ccagccagac 1500

 gaggatttca gtaattgtgc taaagaaatt gccagcaaac attttcgttt 1550

 tgcggagatg ctttactata aagtattaga atctgttatt gagcaggaac 1600

 aaaaaagact aggagacatg gatttatctg gtattctgga acaagatgca 1650

 ttccacagat ctctcttggc ctgctgcctt gaggtcgtca ctttttctta 1700

 taagcctcct gggaattttc catttattac tgaaatattt gatgtgcctc 1750

 tttatcattt ttataaggtg atagaagtat tcattagagc agaagatggc 1800

 ctttgtagag aggtggtaaa acaccttaat cagattgaag aacagatctt 1850

 agatcatttg gcatggaaac cagagtctcc actctgggaa aaaattagag 1900

 acaatgaaaa cagagttcct acatgtgaag aggtcatgcc acctcagaac 1950

 ctggaaaggg cagatgaaat ttgcattgct ggctcccctt tgactcccag 2000

 aagggtgact gaagttcgtg ctgatactgg aggacttgga aggagcataa 2050

 catctccaac cacattatac gataggtaca gctccccacc agccagcact 2100

 accagaaggc ggctatttgt tgagaatgat agcccctctg atggagggac 2150

 gcctgggcgc atgcccccac agcccctagt caatgctgtc cctgtgcaga 2200

 atgtatctgg ggagactgtt tctgtcacac cagttcctgg acagactttg 2250

 gtcaccatgg caaccgccac tgtcacagcc aacaatgggc aaacggtaac 2300

 cattcctgtg caaggtattg ccaatgaaaa tggagggata acattcttcc 2350

 ctgtccaagt caatgttggg gggcaggcac aagctgtgac aggctccatc 2400

 cagcccctca gtgctcaggc cctggctgga agtctgagct ctcaacaggt 2450

 gacaggaaca actttgcaag tccctggtca agtggccatt caacagattt 2500

 ccccaggtgg ccaacagcag aagcaaggcc agtctgtaac cagcagtagt 2550

 aatagaccca ggaagaccag ctctttatcg cttttcttta gaaaggtata 2600

 ccatttagca gctgtccgcc ttcgggatct ctgtgccaaa ctagatattt 2650

 cagatgaatt gaggaaaaaa atctggacct gctttgaatt ctccataatt 2700

 cagtgtcctg aacttatgat ggacagacat ctggaccagt tattaatgtg 2750

 tgccatttat gtgatggcaa aggtcacaaa agaagataag tccttccaga 2800

 acattatgcg ttgttatagg actcagccgc aggcccggag ccaggtgtat 2850

 agaagtgttt tgataaaagg gaaaagaaaa agaagaaatt ctggcagcag 2900

 tgatagcaga agccatcaga attctccaac agaactaaac aaagatagaa 2950

 ccagtagaga ctccagtcca gttatgaggt caagcagcac cttgccagtt 3000

 ccacagccca gcagtgctcc tcccacacct actcgcctca caggtgccaa 3050

 cagtgacatg gaagaagagg agaggggaga cctcattcag ttctacaaca 3100

 acatctacat caaacagatt aagacatttg ccatgaagta ctcacaggca 3150

 aatatggatg ctcctccact ctctccctat ccatttgtaa gaacaggctc 3200

 ccctcgccga atacagttgt ctcaaaatca tcctgtctac atttccccac 3250

 ataaaaatga aacaatgctt tctcctcgag aaaagatttt ctattacttc 3300

 agcaacagtc cttcaaagag actgagagaa attaatagta tgatacgcac 3350

 aggagaaact cctactaaaa agagaggaat tcttttggaa gatggaagtg 3400

 aatcacctgc aaaaagaatt tgcccagaaa atcattctgc cttattacgc 3450

 cgtctccaag atgtagctaa tgaccgtggt tcccactgag gttagtctct 3500

 tgtattaaac tcttcacaaa atctgtttag cagcagcctt taatgcatct 3550

 agattatgga gcttttttcc ttaatccagc tgatgagtta cagcctgtta 3600

 gtaacatgag gggacatttt ggtgagaaat gggacttaac tccttccagt 3650

 gtccttagaa cattttaatt catcccaact gtcttttttt ccctaccact 3700

 cagtgattac tgtcaaggct gcttacaatc caaacttggg tttttggctc 3750

 tggcaaagct tttagaaata ctgcaagaaa tgatgtgtac ccaacgtgag 3800

 cataggaggc ttctgttgac gtctccaaca gaagaactgt gtttcaagtt 3850

 caatcctacc tgttttgtgg tcagctgtag tcctcataaa aagcaaaaca 3900

 aaaattaggt attttgtcct aaaacacctg gtaggagtgt gtgatttttt 3950

 gcattcctga caaaggagag cacacccagg tttggaggtc ctaggtcatt 4000

 agccctcgtc tcccgttccc tttgtgcaca tcttccctct ccccattcgg 4050

 tgtggtgcag tgtgaaaagt ccttgattgt tcgggtgtgc aatgtctgag 4100

 tgaacctgta taagtggagg cactttaggg ctgtaaaatg catgattttg 4150

 taacccagat tttgctgtat atttgtgata gcactttcta caatgtgaac 4200

 tttattaaat acaaaacttc caggctaaac atccaatatt ttctttaatg 4250

 cttttatatt tttttaaaat gttaaaaccc ctatagccac cttttgggaa 4300

 tgttttaaat tctccagttt tttgttatat agggatcaac cagctaagaa 4350

 aagattttaa gtcaagttga attgagggga ttaatatgaa aacttatgac 4400

 ctcttccttt aggagggagt tatctaaaag aaatgtctat taaggtgata 4450

 tatttaaaaa tatttttggg tgttcctggc agtttaaaaa aattggttgg 4500

 agaatttagg tttttattag taccatagta ccatttatac aaattagaaa 4550

 atgttattta acagctgaat tatctataca tatctttatt aatcactatt 4600

 gttccagcag ttttcaagtc aaattaataa tcttattagg gagaaaattc 4650

 aattgtaaat tgaatcagta taaacaaagt tactaggtaa cttcatattg 4700

 ctgagagaaa tatggaactt acattgttca attagaatag tgttctcccc 4750

 aaatatttat aaaacttctc aagatactgc tacgtgtaat tttatatgaa 4800

 gataagtgta tttttcaata aagcatttat aaattaaaaa aaaaaaaaaa 4850

 aaa 4853

<210> 2548
<211> 1139
<212> PRT
<213> Homo sapien

<400> 2548
 Met Pro Ser Gly Gly Asp Gln Ser Pro Pro Pro Pro Pro Pro Pro
   1               5                  10                  15

 Pro Ala Ala Ala Ala Ser Asp Glu Glu Glu Glu Asp Asp Gly Glu
                  20                  25                  30

 Ala Glu Asp Ala Ala Pro Ser Ala Glu Ser Pro Thr Pro Gln Ile
                  35                  40                  45

 Gln Gln Arg Phe Asp Glu Leu Cys Ser Arg Leu Asn Met Asp Glu
                  50                  55                  60

 Ala Ala Arg Pro Glu Ala Trp Asp Ser Tyr Arg Ser Met Ser Glu
                  65                  70                  75

 Ser Tyr Thr Leu Glu Gly Asn Asp Leu His Trp Leu Ala Cys Ala
                  80                  85                  90

 Leu Tyr Val Ala Cys Arg Lys Ser Val Pro Thr Val Ser Lys Gly
                  95                 100                 105

 Thr Val Glu Gly Asn Tyr Val Ser Leu Thr Arg Ile Leu Lys Cys
                 110                 115                 120

 Ser Glu Gln Ser Leu Ile Glu Phe Phe Asn Lys Met Lys Lys Trp
                 125                 130                 135

 Glu Asp Met Ala Asn Leu Pro Pro His Phe Arg Glu Arg Thr Glu
                 140                 145                 150

 Arg Leu Glu Arg Asn Phe Thr Val Ser Ala Val Ile Phe Lys Lys
                 155                 160                 165

 Tyr Glu Pro Ile Phe Gln Asp Ile Phe Lys Tyr Pro Gln Glu Glu
                 170                 175                 180

 Gln Pro Arg Gln Gln Arg Gly Arg Lys Gln Arg Arg Gln Pro Cys
                 185                 190                 195

 Thr Val Ser Glu Ile Phe His Phe Cys Trp Val Leu Phe Ile Tyr
                 200                 205                 210

 Ala Lys Gly Asn Phe Pro Met Ile Ser Asp Asp Leu Val Asn Ser
                 215                 220                 225

 Tyr His Leu Leu Leu Cys Ala Leu Asp Leu Val Tyr Gly Asn Ala
                 230                 235                 240

 Leu Gln Cys Ser Asn Arg Lys Glu Leu Val Asn Pro Asn Phe Lys
                 245                 250                 255

 Gly Leu Ser Glu Asp Phe His Ala Lys Asp Ser Lys Pro Ser Ser
                 260                 265                 270

 Asp Pro Pro Cys Ile Ile Glu Lys Leu Cys Ser Leu His Asp Gly
                 275                 280                 285

 Leu Val Leu Glu Ala Lys Gly Ile Lys Glu His Phe Trp Lys Pro
                 290                 295                 300

 Tyr Ile Arg Lys Leu Tyr Glu Lys Lys Leu Leu Lys Gly Lys Glu
                 305                 310                 315

 Glu Asn Leu Thr Gly Phe Leu Glu Pro Gly Asn Phe Gly Glu Ser
                 320                 325                 330

 Phe Lys Ala Ile Asn Lys Ala Tyr Glu Glu Tyr Val Leu Ser Val
                 335                 340                 345

 Gly Asn Leu Asp Glu Arg Ile Phe Leu Gly Glu Asp Ala Glu Glu
                 350                 355                 360

 Glu Ile Gly Thr Leu Ser Arg Cys Leu Asn Ala Gly Ser Gly Thr
                 365                 370                 375

 Glu Thr Ala Glu Arg Val Gln Met Lys Asn Ile Leu Gln Gln His
                 380                 385                 390

 Phe Asp Lys Ser Lys Ala Leu Arg Ile Ser Thr Pro Leu Thr Gly
                 395                 400                 405

 Val Arg Tyr Ile Lys Glu Asn Ser Pro Cys Val Thr Pro Val Ser
                 410                 415                 420

 Thr Ala Thr His Ser Leu Ser Arg Leu His Thr Met Leu Thr Gly
                 425                 430                 435

 Leu Arg Asn Ala Pro Ser Glu Lys Leu Glu Gln Ile Leu Arg Thr
                 440                 445                 450

 Cys Ser Arg Asp Pro Thr Gln Ala Ile Ala Asn Arg Leu Lys Glu
                 455                 460                 465

 Met Phe Glu Ile Tyr Ser Gln His Phe Gln Pro Asp Glu Asp Phe
                 470                 475                 480

 Ser Asn Cys Ala Lys Glu Ile Ala Ser Lys His Phe Arg Phe Ala
                 485                 490                 495

 Glu Met Leu Tyr Tyr Lys Val Leu Glu Ser Val Ile Glu Gln Glu
                 500                 505                 510

 Gln Lys Arg Leu Gly Asp Met Asp Leu Ser Gly Ile Leu Glu Gln
                 515                 520                 525

 Asp Ala Phe His Arg Ser Leu Leu Ala Cys Cys Leu Glu Val Val
                 530                 535                 540

 Thr Phe Ser Tyr Lys Pro Pro Gly Asn Phe Pro Phe Ile Thr Glu
                 545                 550                 555

 Ile Phe Asp Val Pro Leu Tyr His Phe Tyr Lys Val Ile Glu Val
                 560                 565                 570

 Phe Ile Arg Ala Glu Asp Gly Leu Cys Arg Glu Val Val Lys His
                 575                 580                 585

 Leu Asn Gln Ile Glu Glu Gln Ile Leu Asp His Leu Ala Trp Lys
                 590                 595                 600

 Pro Glu Ser Pro Leu Trp Glu Lys Ile Arg Asp Asn Glu Asn Arg
                 605                 610                 615

 Val Pro Thr Cys Glu Glu Val Met Pro Pro Gln Asn Leu Glu Arg
                 620                 625                 630

 Ala Asp Glu Ile Cys Ile Ala Gly Ser Pro Leu Thr Pro Arg Arg
                 635                 640                 645

 Val Thr Glu Val Arg Ala Asp Thr Gly Gly Leu Gly Arg Ser Ile
                 650                 655                 660

 Thr Ser Pro Thr Thr Leu Tyr Asp Arg Tyr Ser Ser Pro Pro Ala
                 665                 670                 675

 Ser Thr Thr Arg Arg Arg Leu Phe Val Glu Asn Asp Ser Pro Ser
                 680                 685                 690

 Asp Gly Gly Thr Pro Gly Arg Met Pro Pro Gln Pro Leu Val Asn
                 695                 700                 705

 Ala Val Pro Val Gln Asn Val Ser Gly Glu Thr Val Ser Val Thr
                 710                 715                 720

 Pro Val Pro Gly Gln Thr Leu Val Thr Met Ala Thr Ala Thr Val
                 725                 730                 735

 Thr Ala Asn Asn Gly Gln Thr Val Thr Ile Pro Val Gln Gly Ile
                 740                 745                 750

 Ala Asn Glu Asn Gly Gly Ile Thr Phe Phe Pro Val Gln Val Asn
                 755                 760                 765

 Val Gly Gly Gln Ala Gln Ala Val Thr Gly Ser Ile Gln Pro Leu
                 770                 775                 780

 Ser Ala Gln Ala Leu Ala Gly Ser Leu Ser Ser Gln Gln Val Thr
                 785                 790                 795

 Gly Thr Thr Leu Gln Val Pro Gly Gln Val Ala Ile Gln Gln Ile
                 800                 805                 810

 Ser Pro Gly Gly Gln Gln Gln Lys Gln Gly Gln Ser Val Thr Ser
                 815                 820                 825

 Ser Ser Asn Arg Pro Arg Lys Thr Ser Ser Leu Ser Leu Phe Phe
                 830                 835                 840

 Arg Lys Val Tyr His Leu Ala Ala Val Arg Leu Arg Asp Leu Cys
                 845                 850                 855

 Ala Lys Leu Asp Ile Ser Asp Glu Leu Arg Lys Lys Ile Trp Thr
                 860                 865                 870

 Cys Phe Glu Phe Ser Ile Ile Gln Cys Pro Glu Leu Met Met Asp
                 875                 880                 885

 Arg His Leu Asp Gln Leu Leu Met Cys Ala Ile Tyr Val Met Ala
                 890                 895                 900

 Lys Val Thr Lys Glu Asp Lys Ser Phe Gln Asn Ile Met Arg Cys
                 905                 910                 915

 Tyr Arg Thr Gln Pro Gln Ala Arg Ser Gln Val Tyr Arg Ser Val
                 920                 925                 930

 Leu Ile Lys Gly Lys Arg Lys Arg Arg Asn Ser Gly Ser Ser Asp
                 935                 940                 945

 Ser Arg Ser His Gln Asn Ser Pro Thr Glu Leu Asn Lys Asp Arg
                 950                 955                 960

 Thr Ser Arg Asp Ser Ser Pro Val Met Arg Ser Ser Ser Thr Leu
                 965                 970                 975

 Pro Val Pro Gln Pro Ser Ser Ala Pro Pro Thr Pro Thr Arg Leu
                 980                 985                 990

 Thr Gly Ala Asn Ser Asp Met Glu Glu Glu Glu Arg Gly Asp Leu
                 995                1000                1005

 Ile Gln Phe Tyr Asn Asn Ile Tyr Ile Lys Gln Ile Lys Thr Phe
                1010                1015                1020

 Ala Met Lys Tyr Ser Gln Ala Asn Met Asp Ala Pro Pro Leu Ser
                1025                1030                1035

 Pro Tyr Pro Phe Val Arg Thr Gly Ser Pro Arg Arg Ile Gln Leu
                1040                1045                1050

 Ser Gln Asn His Pro Val Tyr Ile Ser Pro His Lys Asn Glu Thr
                1055                1060                1065

 Met Leu Ser Pro Arg Glu Lys Ile Phe Tyr Tyr Phe Ser Asn Ser
                1070                1075                1080

 Pro Ser Lys Arg Leu Arg Glu Ile Asn Ser Met Ile Arg Thr Gly
                1085                1090                1095

 Glu Thr Pro Thr Lys Lys Arg Gly Ile Leu Leu Glu Asp Gly Ser
                1100                1105                1110

 Glu Ser Pro Ala Lys Arg Ile Cys Pro Glu Asn His Ser Ala Leu
                1115                1120                1125

 Leu Arg Arg Leu Gln Asp Val Ala Asn Asp Arg Gly Ser His
                1130                1135

<210> 2549
<211> 4853
<212> DNA
<213> Homo sapien

<400> 2549
 ttcgccgttt gaattgctgc gggcccgggc cctcacctca cctgaggtcc 50

 ggccgcccag gggtgcgcta tgccgtcggg aggtgaccag tcgccaccgc 100

 ccccgcctcc ccctccggcg gcggcagcct cggatgagga ggaggaggac 150

 gacggcgagg cggaagacgc cgcgccgtct gccgagtcgc ccacccctca 200

 gatccagcag cggttcgacg agctgtgcag ccgcctcaac atggacgagg 250

 cggcgcggcc cgaggcctgg gacagctacc gcagcatgag cgaaagctac 300

 acgctggagg gaaatgatct tcattggtta gcatgtgcct tatatgtggc 350

 ttgcagaaaa tctgttccaa ctgtaagcaa agggacagtg gaaggaaact 400

 atgtatcttt aactagaatc ctgaaatgtt cagagcagag cttaatcgaa 450

 ttttttaata agatgaagaa gtgggaagac atggcaaatc tacccccaca 500

 tttcagagaa cgtactgaga gattagaaag aaacttcact gtttctgctg 550

 taatttttaa gaaatatgaa cccatttttc aggacatctt taaataccct 600

 caagaggagc aacctcgtca gcagcgagga aggaaacagc ggcgacagcc 650

 ctgtactgtg tctgaaattt tccatttttg ttgggtgctt tttatatatg 700

 caaaaggtaa tttccccatg attagtgatg atttggtcaa ttcttatcac 750

 ctgctgctgt gtgctttgga cttagtttat ggaaatgcac ttcagtgttc 800

 taatcgtaaa gaacttgtga accctaattt taaaggctta tctgaagatt 850

 ttcatgctaa agattctaaa ccttcctctg accccccttg tatcattgag 900

 aaactgtgtt ccttacatga tggcctagtt ttggaagcaa aggggataaa 950

 ggaacatttc tggaaaccct atattaggaa actttatgaa aaaaagctcc 1000

 ttaagggaaa agaagaaaat ctcactgggt ttctagaacc tgggaacttt 1050

 ggagagagtt ttaaagccat caataaggcc tatgaggagt atgttttatc 1100

 tgttgggaat ttagatgagc ggatatttct tggagaggat gctgaggagg 1150

 aaattgggac tctctcaagg tgtctgaacg ctggttcagg aacagagact 1200

 gctgaaaggg tgcagatgaa aaacatctta cagcagcatt ttgacaagtc 1250

 caaagcactt agaatctcca caccactaac tggtgttagg tacattaagg 1300

 agaatagccc ttgtgtgact ccagtttcta cagctacgca tagcttgagt 1350

 cgtcttcaca ccatgctgac aggcctcagg aatgcaccaa gtgagaaact 1400

 ggaacagatt ctcaggacat gttccagaga tccaacccag gctattgcta 1450

 acagactgaa agaaatgttt gaaatatatt ctcagcattt ccagccagac 1500

 gaggatttca gtaattgtgc taaagaaatt gccagcaaac attttcgttt 1550

 tgcggagatg ctttactata aagtattaga atctgttatt gagcaggaac 1600

 aaaaaagact aggagacatg gatttatctg gtattctgga acaagatgca 1650

 ttccacagat ctctcttggc ctgctgcctt gaggtcgtca ctttttctta 1700

 taagcctcct gggaattttc catttattac tgaaatattt gatgtgcctc 1750

 tttatcattt ttataaggtg atagaagtat tcattagagc agaagatggc 1800

 ctttgtagag aggtggtaaa acaccttaat cagattgaag aacagatctt 1850

 agatcatttg gcatggaaac cagagtctcc actctgggaa aaaattagag 1900

 acaatgaaaa cagagttcct acatgtgaag aggtcatgcc acctcagaac 1950

 ctggaaaggg cagatgaaat ttgcattgct ggctcccctt tgactcccag 2000

 aagggtgact gaagttcgtg ctgatactgg aggacttgga aggagcataa 2050

 catctccaac cacattatac gataggtaca gctccccacc agccagcact 2100

 accagaaggc ggctatttgt tgagaatgat agcccctctg atggagggac 2150

 gcctgggcgc atgcccccac agcccctagt caatgctgtc cctgtgcaga 2200

 atgtatctgg ggagactgtt tctgtcacac cagttcctgg acagactttg 2250

 gtcaccatgg caaccgccac tgtcacagcc aacaatgggc aaacggtaac 2300

 cattcctgtg caaggtattg ccaatgaaaa tggagggata acattcttcc 2350

 ctgtccaagt caatgttggg gggcaggcac aagctgtgac aggctccatc 2400

 cagcccctca gtgctcaggc cctggctgga agtctgagct ctcaacaggt 2450

 gacaggaaca actttgcaag tccctggtca agtggccatt caacagattt 2500

 ccccaggtgg ccaacagcag aagcaaggcc agtctgtaac cagcagtagt 2550

 aatagaccca ggaagaccag ctctttatcg cttttcttta gaaaggtata 2600

 ccatttagca gctgtccgcc ttcgggatct ctgtgccaaa ctagatattt 2650

 cagatgaatt gaggaaaaaa atctggacct gctttgaatt ctccataatt 2700

 cagtgtcctg aacttatgat ggacagacat ctggaccagt tattaatgtg 2750

 tgccatttat gtgatggcaa aggtcacaaa agaagataag tccttccaga 2800

 acattatgcg ttgttatagg actcagccgc aggcccggag ccaggtgtat 2850

 agaagtgttt tgataaaagg gaaaagaaaa agaagaaatt ctggcagcag 2900

 tgatagcaga agccatcaga attctccaac agaactaaac aaagatagaa 2950

 ccagtagaga ctccagtcca gttatgaggt caagcagcac cttgccagtt 3000

 ccacagccca gcagtgctcc tcccacacct actcgcctca caggtgccaa 3050

 cagtgacatg gaagaagagg agaggggaga cctcattcag ttctacaaca 3100

 acatctacat caaacagatt aagacatttg ccatgaagta ctcacaggca 3150

 aatatggatg ctcctccact ctctccctat ccatttgtaa gaacaggctc 3200

 ccctcgccga atacagttgt ctcaaaatca tcctgtctac atttccccac 3250

 ataaaaatga aacaatgctt tctcctcgag aaaagatttt ctattacttc 3300

 agcaacagtc cttcaaagag actgagagaa attaatagta tgatacgcac 3350

 aggagaaact cctactaaaa agagaggaat tcttttggaa gatggaagtg 3400

 aatcacctgc aaaaagaatt tgcccagaaa atcattctgc cttattacgc 3450

 cgtctccaag atgtagctaa tgaccgtggt tcccactgag gttagtctct 3500

 tgtattaaac tcttcacaaa atctgtttag cagcagcctt taatgcatct 3550

 agattatgga gcttttttcc ttaatccagc tgatgagtta cagcctgtta 3600

 gtaacatgag gggacatttt ggtgagaaat gggacttaac tccttccagt 3650

 gtccttagaa cattttaatt catcccaact gtcttttttt ccctaccact 3700

 cagtgattac tgtcaaggct gcttacaatc caaacttggg tttttggctc 3750

 tggcaaagct tttagaaata ctgcaagaaa tgatgtgtac ccaacgtgag 3800

 cataggaggc ttctgttgac gtctccaaca gaagaactgt gtttcaagtt 3850

 caatcctacc tgttttgtgg tcagctgtag tcctcataaa aagcaaaaca 3900

 aaaattaggt attttgtcct aaaacacctg gtaggagtgt gtgatttttt 3950

 gcattcctga caaaggagag cacacccagg tttggaggtc ctaggtcatt 4000

 agccctcgtc tcccgttccc tttgtgcaca tcttccctct ccccattcgg 4050

 tgtggtgcag tgtgaaaagt ccttgattgt tcgggtgtgc aatgtctgag 4100

 tgaacctgta taagtggagg cactttaggg ctgtaaaatg catgattttg 4150

 taacccagat tttgctgtat atttgtgata gcactttcta caatgtgaac 4200

 tttattaaat acaaaacttc caggctaaac atccaatatt ttctttaatg 4250

 cttttatatt tttttaaaat gttaaaaccc ctatagccac cttttgggaa 4300

 tgttttaaat tctccagttt tttgttatat agggatcaac cagctaagaa 4350

 aagattttaa gtcaagttga attgagggga ttaatatgaa aacttatgac 4400

 ctcttccttt aggagggagt tatctaaaag aaatgtctat taaggtgata 4450

 tatttaaaaa tatttttggg tgttcctggc agtttaaaaa aattggttgg 4500

 agaatttagg tttttattag taccatagta ccatttatac aaattagaaa 4550

 atgttattta acagctgaat tatctataca tatctttatt aatcactatt 4600

 gttccagcag ttttcaagtc aaattaataa tcttattagg gagaaaattc 4650

 aattgtaaat tgaatcagta taaacaaagt tactaggtaa cttcatattg 4700

 ctgagagaaa tatggaactt acattgttca attagaatag tgttctcccc 4750

 aaatatttat aaaacttctc aagatactgc tacgtgtaat tttatatgaa 4800

 gataagtgta tttttcaata aagcatttat aaattaaaaa aaaaaaaaaa 4850

 aaa 4853

<210> 2550
<211> 1139
<212> PRT
<213> Homo sapien

<400> 2550
 Met Pro Ser Gly Gly Asp Gln Ser Pro Pro Pro Pro Pro Pro Pro
   1               5                  10                  15

 Pro Ala Ala Ala Ala Ser Asp Glu Glu Glu Glu Asp Asp Gly Glu
                  20                  25                  30

 Ala Glu Asp Ala Ala Pro Ser Ala Glu Ser Pro Thr Pro Gln Ile
                  35                  40                  45

 Gln Gln Arg Phe Asp Glu Leu Cys Ser Arg Leu Asn Met Asp Glu
                  50                  55                  60

 Ala Ala Arg Pro Glu Ala Trp Asp Ser Tyr Arg Ser Met Ser Glu
                  65                  70                  75

 Ser Tyr Thr Leu Glu Gly Asn Asp Leu His Trp Leu Ala Cys Ala
                  80                  85                  90

 Leu Tyr Val Ala Cys Arg Lys Ser Val Pro Thr Val Ser Lys Gly
                  95                 100                 105

 Thr Val Glu Gly Asn Tyr Val Ser Leu Thr Arg Ile Leu Lys Cys
                 110                 115                 120

 Ser Glu Gln Ser Leu Ile Glu Phe Phe Asn Lys Met Lys Lys Trp
                 125                 130                 135

 Glu Asp Met Ala Asn Leu Pro Pro His Phe Arg Glu Arg Thr Glu
                 140                 145                 150

 Arg Leu Glu Arg Asn Phe Thr Val Ser Ala Val Ile Phe Lys Lys
                 155                 160                 165

 Tyr Glu Pro Ile Phe Gln Asp Ile Phe Lys Tyr Pro Gln Glu Glu
                 170                 175                 180

 Gln Pro Arg Gln Gln Arg Gly Arg Lys Gln Arg Arg Gln Pro Cys
                 185                 190                 195

 Thr Val Ser Glu Ile Phe His Phe Cys Trp Val Leu Phe Ile Tyr
                 200                 205                 210

 Ala Lys Gly Asn Phe Pro Met Ile Ser Asp Asp Leu Val Asn Ser
                 215                 220                 225

 Tyr His Leu Leu Leu Cys Ala Leu Asp Leu Val Tyr Gly Asn Ala
                 230                 235                 240

 Leu Gln Cys Ser Asn Arg Lys Glu Leu Val Asn Pro Asn Phe Lys
                 245                 250                 255

 Gly Leu Ser Glu Asp Phe His Ala Lys Asp Ser Lys Pro Ser Ser
                 260                 265                 270

 Asp Pro Pro Cys Ile Ile Glu Lys Leu Cys Ser Leu His Asp Gly
                 275                 280                 285

 Leu Val Leu Glu Ala Lys Gly Ile Lys Glu His Phe Trp Lys Pro
                 290                 295                 300

 Tyr Ile Arg Lys Leu Tyr Glu Lys Lys Leu Leu Lys Gly Lys Glu
                 305                 310                 315

 Glu Asn Leu Thr Gly Phe Leu Glu Pro Gly Asn Phe Gly Glu Ser
                 320                 325                 330

 Phe Lys Ala Ile Asn Lys Ala Tyr Glu Glu Tyr Val Leu Ser Val
                 335                 340                 345

 Gly Asn Leu Asp Glu Arg Ile Phe Leu Gly Glu Asp Ala Glu Glu
                 350                 355                 360

 Glu Ile Gly Thr Leu Ser Arg Cys Leu Asn Ala Gly Ser Gly Thr
                 365                 370                 375

 Glu Thr Ala Glu Arg Val Gln Met Lys Asn Ile Leu Gln Gln His
                 380                 385                 390

 Phe Asp Lys Ser Lys Ala Leu Arg Ile Ser Thr Pro Leu Thr Gly
                 395                 400                 405

 Val Arg Tyr Ile Lys Glu Asn Ser Pro Cys Val Thr Pro Val Ser
                 410                 415                 420

 Thr Ala Thr His Ser Leu Ser Arg Leu His Thr Met Leu Thr Gly
                 425                 430                 435

 Leu Arg Asn Ala Pro Ser Glu Lys Leu Glu Gln Ile Leu Arg Thr
                 440                 445                 450

 Cys Ser Arg Asp Pro Thr Gln Ala Ile Ala Asn Arg Leu Lys Glu
                 455                 460                 465

 Met Phe Glu Ile Tyr Ser Gln His Phe Gln Pro Asp Glu Asp Phe
                 470                 475                 480

 Ser Asn Cys Ala Lys Glu Ile Ala Ser Lys His Phe Arg Phe Ala
                 485                 490                 495

 Glu Met Leu Tyr Tyr Lys Val Leu Glu Ser Val Ile Glu Gln Glu
                 500                 505                 510

 Gln Lys Arg Leu Gly Asp Met Asp Leu Ser Gly Ile Leu Glu Gln
                 515                 520                 525

 Asp Ala Phe His Arg Ser Leu Leu Ala Cys Cys Leu Glu Val Val
                 530                 535                 540

 Thr Phe Ser Tyr Lys Pro Pro Gly Asn Phe Pro Phe Ile Thr Glu
                 545                 550                 555

 Ile Phe Asp Val Pro Leu Tyr His Phe Tyr Lys Val Ile Glu Val
                 560                 565                 570

 Phe Ile Arg Ala Glu Asp Gly Leu Cys Arg Glu Val Val Lys His
                 575                 580                 585

 Leu Asn Gln Ile Glu Glu Gln Ile Leu Asp His Leu Ala Trp Lys
                 590                 595                 600

 Pro Glu Ser Pro Leu Trp Glu Lys Ile Arg Asp Asn Glu Asn Arg
                 605                 610                 615

 Val Pro Thr Cys Glu Glu Val Met Pro Pro Gln Asn Leu Glu Arg
                 620                 625                 630

 Ala Asp Glu Ile Cys Ile Ala Gly Ser Pro Leu Thr Pro Arg Arg
                 635                 640                 645

 Val Thr Glu Val Arg Ala Asp Thr Gly Gly Leu Gly Arg Ser Ile
                 650                 655                 660

 Thr Ser Pro Thr Thr Leu Tyr Asp Arg Tyr Ser Ser Pro Pro Ala
                 665                 670                 675

 Ser Thr Thr Arg Arg Arg Leu Phe Val Glu Asn Asp Ser Pro Ser
                 680                 685                 690

 Asp Gly Gly Thr Pro Gly Arg Met Pro Pro Gln Pro Leu Val Asn
                 695                 700                 705

 Ala Val Pro Val Gln Asn Val Ser Gly Glu Thr Val Ser Val Thr
                 710                 715                 720

 Pro Val Pro Gly Gln Thr Leu Val Thr Met Ala Thr Ala Thr Val
                 725                 730                 735

 Thr Ala Asn Asn Gly Gln Thr Val Thr Ile Pro Val Gln Gly Ile
                 740                 745                 750

 Ala Asn Glu Asn Gly Gly Ile Thr Phe Phe Pro Val Gln Val Asn
                 755                 760                 765

 Val Gly Gly Gln Ala Gln Ala Val Thr Gly Ser Ile Gln Pro Leu
                 770                 775                 780

 Ser Ala Gln Ala Leu Ala Gly Ser Leu Ser Ser Gln Gln Val Thr
                 785                 790                 795

 Gly Thr Thr Leu Gln Val Pro Gly Gln Val Ala Ile Gln Gln Ile
                 800                 805                 810

 Ser Pro Gly Gly Gln Gln Gln Lys Gln Gly Gln Ser Val Thr Ser
                 815                 820                 825

 Ser Ser Asn Arg Pro Arg Lys Thr Ser Ser Leu Ser Leu Phe Phe
                 830                 835                 840

 Arg Lys Val Tyr His Leu Ala Ala Val Arg Leu Arg Asp Leu Cys
                 845                 850                 855

 Ala Lys Leu Asp Ile Ser Asp Glu Leu Arg Lys Lys Ile Trp Thr
                 860                 865                 870

 Cys Phe Glu Phe Ser Ile Ile Gln Cys Pro Glu Leu Met Met Asp
                 875                 880                 885

 Arg His Leu Asp Gln Leu Leu Met Cys Ala Ile Tyr Val Met Ala
                 890                 895                 900

 Lys Val Thr Lys Glu Asp Lys Ser Phe Gln Asn Ile Met Arg Cys
                 905                 910                 915

 Tyr Arg Thr Gln Pro Gln Ala Arg Ser Gln Val Tyr Arg Ser Val
                 920                 925                 930

 Leu Ile Lys Gly Lys Arg Lys Arg Arg Asn Ser Gly Ser Ser Asp
                 935                 940                 945

 Ser Arg Ser His Gln Asn Ser Pro Thr Glu Leu Asn Lys Asp Arg
                 950                 955                 960

 Thr Ser Arg Asp Ser Ser Pro Val Met Arg Ser Ser Ser Thr Leu
                 965                 970                 975

 Pro Val Pro Gln Pro Ser Ser Ala Pro Pro Thr Pro Thr Arg Leu
                 980                 985                 990

 Thr Gly Ala Asn Ser Asp Met Glu Glu Glu Glu Arg Gly Asp Leu
                 995                1000                1005

 Ile Gln Phe Tyr Asn Asn Ile Tyr Ile Lys Gln Ile Lys Thr Phe
                1010                1015                1020

 Ala Met Lys Tyr Ser Gln Ala Asn Met Asp Ala Pro Pro Leu Ser
                1025                1030                1035

 Pro Tyr Pro Phe Val Arg Thr Gly Ser Pro Arg Arg Ile Gln Leu
                1040                1045                1050

 Ser Gln Asn His Pro Val Tyr Ile Ser Pro His Lys Asn Glu Thr
                1055                1060                1065

 Met Leu Ser Pro Arg Glu Lys Ile Phe Tyr Tyr Phe Ser Asn Ser
                1070                1075                1080

 Pro Ser Lys Arg Leu Arg Glu Ile Asn Ser Met Ile Arg Thr Gly
                1085                1090                1095

 Glu Thr Pro Thr Lys Lys Arg Gly Ile Leu Leu Glu Asp Gly Ser
                1100                1105                1110

 Glu Ser Pro Ala Lys Arg Ile Cys Pro Glu Asn His Ser Ala Leu
                1115                1120                1125

 Leu Arg Arg Leu Gln Asp Val Ala Asn Asp Arg Gly Ser His
                1130                1135

<210> 2551
<211> 2078
<212> DNA
<213> Homo sapien

<400> 2551
 tgggcaatta accaagccat agccaatgaa tatgaagtcc ggagaaagct 50

 gctaataaaa cgtttggatg tcactgtaca atcctttggc tggtctgaca 100

 gagctaagag ccagacagaa aaattagcca aggtttacca gccgaaacgt 150

 tcagtcttat cccctaaaac tactatttct gttgcccatc ttttggctgc 200

 aaggcaggac ttgtcaaaga ttttaaggac aagcagcggc tctataagag 250

 aaaagactgc ctgtgccatc aataaggtgt tgatgggcag ggtgcctgac 300

 agaggtggta gacccaatga aatcgaacct ccacccccag agatgccacc 350

 gtggcagaag aggcaagatg gcccccagca gcaaacagga ggccgagtag 400

 gagggagagg tggctatgaa cattcctcat acggaggacg aggaggtcat 450

 gaacaaggag gcgggagagg tggacgtggt ggctatgacc atggtggccg 500

 agggggagga agaggaaata agcatcaagg aggctggaca gatggaggga 550

 gtggtggagg aggtggctac caagatggtg gttatcgaga ttcaggtttc 600

 cagccaggtg gctatcatgg tggccacagc agtggtggct atcaaggcgg 650

 aggttatggt ggcttccaaa catcttcttc atatacagga agtggatacc 700

 agggtggtgg ctaccagcag gacaatagat accaagatgg cgggcaccat 750

 ggtgatcgtg gtggtggtcg tggtgggcga ggtggtcgtg gaggccgagg 800

 tggtcgtgca ggccagggag gaggctgggg aggaagaggg agccagaatt 850

 atcaccaagg gggtcaattt gaacagcatt tccagcatgg aggttatcag 900

 tataatcatt ctggatttgg acagggaaga cattacacta gttgaggcta 950

 ccgaacttta cattttgcta gagctcaagt aatagaaact tagtttcaga 1000

 atcctgaatt cagcacctat tttgaattaa tgtgagacca caggtggcag 1050

 gcagattcct gcttggcata agcatttgta ggtcttcatt caattctgtt 1100

 agattttttt attggactta cataatgccg tttatttgag aaacacataa 1150

 catctctcct tcctatgaaa aattttttaa aaggtggtta aaattgcctt 1200

 taattgccca gtagactaat tccacagtca gaacatgcaa acttttttga 1250

 agaaattact tgaataagta gttttcatgt tttcaatatg cagttttgaa 1300

 aatgaggatt cacctagact tttttagatt tactactagg aaaccttcct 1350

 catatgaata accatttata tgtgttttgc ttaaagtatt ccaatgccta 1400

 ttttccaagc acagttctgc cccccggttg acttttatgc cacgtgtgct 1450

 tcatgatgga acttttaggt cagttcctat taaatgagct cttctgcaga 1500

 tagcacattc agtagcctta ttttgttgat ggaatactgt atcatatgct 1550

 caactctgaa aaccttgaac acggccaaaa tccataaaga ttataaaagc 1600

 aaactaagtt gtgaagctat agtacatgta ggcatttagt taagtatagc 1650

 aattcaaact gacctgcatc catccaaaac aaattcctcc ttcaacctta 1700

 tttttacttg aaatttgcta gaagaaatag caaaccgaaa tttgttttat 1750

 gcatgagtta ataccactgg ctcagcaaat acaagttagt ttgctttaag 1800

 caggtaactt tttttgtaat ggaagaaatg cactacaaag ttaagacaga 1850

 tttttgctaa gtgcaggagg ccctttatta ttgctgcaga aaacaaaagc 1900

 ctggctgagt tgatgtttta cattctccct tactgaaatc tacatgacat 1950

 gatgcttctt gctgggtttt tgtacatgta aacattgtca agctgtgaaa 2000

 gaaaatggct ggaggtgtgc tttgtgtgaa aggtgagcaa taaagtatct 2050

 gttaagttca aaaaaaaaaa aaaaaaaa 2078

<210> 2552
<211> 314
<212> PRT
<213> Homo sapien

<400> 2552
 Trp Ala Ile Asn Gln Ala Ile Ala Asn Glu Tyr Glu Val Arg Arg
   1               5                  10                  15

 Lys Leu Leu Ile Lys Arg Leu Asp Val Thr Val Gln Ser Phe Gly
                  20                  25                  30

 Trp Ser Asp Arg Ala Lys Ser Gln Thr Glu Lys Leu Ala Lys Val
                  35                  40                  45

 Tyr Gln Pro Lys Arg Ser Val Leu Ser Pro Lys Thr Thr Ile Ser
                  50                  55                  60

 Val Ala His Leu Leu Ala Ala Arg Gln Asp Leu Ser Lys Ile Leu
                  65                  70                  75

 Arg Thr Ser Ser Gly Ser Ile Arg Glu Lys Thr Ala Cys Ala Ile
                  80                  85                  90

 Asn Lys Val Leu Met Gly Arg Val Pro Asp Arg Gly Gly Arg Pro
                  95                 100                 105

 Asn Glu Ile Glu Pro Pro Pro Pro Glu Met Pro Pro Trp Gln Lys
                 110                 115                 120

 Arg Gln Asp Gly Pro Gln Gln Gln Thr Gly Gly Arg Val Gly Gly
                 125                 130                 135

 Arg Gly Gly Tyr Glu His Ser Ser Tyr Gly Gly Arg Gly Gly His
                 140                 145                 150

 Glu Gln Gly Gly Gly Arg Gly Gly Arg Gly Gly Tyr Asp His Gly
                 155                 160                 165

 Gly Arg Gly Gly Gly Arg Gly Asn Lys His Gln Gly Gly Trp Thr
                 170                 175                 180

 Asp Gly Gly Ser Gly Gly Gly Gly Gly Tyr Gln Asp Gly Gly Tyr
                 185                 190                 195

 Arg Asp Ser Gly Phe Gln Pro Gly Gly Tyr His Gly Gly His Ser
                 200                 205                 210

 Ser Gly Gly Tyr Gln Gly Gly Gly Tyr Gly Gly Phe Gln Thr Ser
                 215                 220                 225

 Ser Ser Tyr Thr Gly Ser Gly Tyr Gln Gly Gly Gly Tyr Gln Gln
                 230                 235                 240

 Asp Asn Arg Tyr Gln Asp Gly Gly His His Gly Asp Arg Gly Gly
                 245                 250                 255

 Gly Arg Gly Gly Arg Gly Gly Arg Gly Gly Arg Gly Gly Arg Ala
                 260                 265                 270

 Gly Gln Gly Gly Gly Trp Gly Gly Arg Gly Ser Gln Asn Tyr His
                 275                 280                 285

 Gln Gly Gly Gln Phe Glu Gln His Phe Gln His Gly Gly Tyr Gln
                 290                 295                 300

 Tyr Asn His Ser Gly Phe Gly Gln Gly Arg His Tyr Thr Ser
                 305                 310

<210> 2553
<211> 2651
<212> DNA
<213> Homo sapien

<400> 2553
 agagcagtaa gcttgtgata aaggccaatt ccaggtagct cttgaaggtg 50

 atagccatct actttccagt ggctgccaac cacagggagt gccagttaac 100

 actggaagga ttaaggcaag gtcccttctc ttgagactcc cctctgagat 150

 ctgaaaaatg aagtggctta ggaacatcag cagtgaagaa ctgccaagag 200

 ttggtgaagg ttgtctcttc cgagggcctt ctgaagacag ggctcttgaa 250

 cagacaagtg gaagggctgt accagggata aaggaaagaa gtgcctgtcc 300

 agcagggagc ttgaatttaa gttccatgta tgaagtcatt ggctctatct 350

 gcatttttct gtcattctct tcatttgttt taaggtggaa aattttctta 400

 cagttgatgc aaagtatcaa ctactttacc ctaccttctc cccttttaga 450

 tgggttcttc ctgagttttg gagtcttgta tgattatcag tattcccctg 500

 tcaaaatcaa atctattcag gtttcttcac tgttgagaac acctaaatgt 550

 ttttattttt gagaagtggg gacagagtct cactatgtca cccaggctgg 600

 agtgcaatgg catgatctca gctcactgca accttcgcct cctgggttca 650

 agcgattctc ctgcctccgc ctcctgagta gctgggatta taggcacgca 700

 ccaccacgcc cagctaattt tttgtatttt tagtagagac agagtttcac 750

 catgttggcc aggctggtct tgaactcctg accttgtgat ccacccacct 800

 cggcctccca gagtgctggg attacaggca tgagccacca cgcttggcta 850

 agaacaccta aatttttatg tttcttggct caaaaaccag ttccatttct 900

 aatgttgtcc tcacaagaag gctaattggt ggtgagacag caggggagga 950

 ggaagagctg tggtttgtaa cttgttcaac tcaggcaata agcgatttta 1000

 gctttattta aagtcttctg tccagcttta agcactttgt aagacatggc 1050

 tgaaagtagc ttttctatca gaattgcaga tagtcatgtt gggctaacag 1100

 tcaattggat atattccttt acctcacatg accccagcaa ctgtggtggt 1150

 atctagaggt gaaacaggca agtgaaatgg acacctctgc tgtgaatgtt 1200

 ttagagaagg aaattcaaaa aatgttgtaa ctgaaagcac tgttgaatat 1250

 gggtatcggc tttctttttc actttgactc ttaacattat cagtcaactt 1300

 ccacattaat gaaagttgac catagttatt tccaaataaa aagaaaccaa 1350

 ctcttaccag gtcttggact gtgatgtcat attattcagt tttatgcttg 1400

 ttcctgagca gaactcataa gagtgacata gtcagctgct gacggcacct 1450

 cagccacgcc actcttactc agttcagtgg gtgtgcttgc gtggtaggat 1500

 gtggtgcagc cctctctacg ctcttctatt tttggtatat ttcctatcta 1550

 accttcaaat agcttccaat tctttttttc ttggactggc ttcattctga 1600

 atttgtgcta aaataatctt tcataaagag acctcagttt atagcgtaac 1650

 agactacaca atgcactgat gttttcataa tgtttaaggg acccactgca 1700

 agaagcttgc tgcctccttt taattgtatt catttagatt ttgattttcc 1750

 atgttaagaa ggtgaggtcc atgttggtgc ccttcagagt agagaaccat 1800

 gtaaacatta ggaatgaaca gaggccttag gaatgaatag agagtttgcc 1850

 ttatacaatt tcctgttaca aagctctccc tctcatgcaa agtagggaac 1900

 accttttgag catctttgaa tttgacaaat ggtgctgttg caaacacttt 1950

 ttttttgaga tgaagtctcg cggttgtcac ccgggctgga gtgcagtggc 2000

 gtgatctcgg ctcactgcaa cttccacctc ctgggttcca gcagttctcc 2050

 tgcctcagcc tcccaagtag ctgagattac aggcgcctgc caccccacct 2100

 ggctgatttt tgtaatttta gtagagacgg ggtttcacca tgttggccag 2150

 gctgattaac tcctgacctc aggtgatcca cctttctcgg cctcccaaag 2200

 tgctgggatt acgggtgtga gccaccgtgc ccggcctgca aacacatttt 2250

 aattgacaac actagggctg ttgtacaaaa tagtaatgat agccatggaa 2300

 gttttacctt attctgtgag aagtgttctt aaacttatta agtgtctaaa 2350

 ctaaggttta gtgctttttt aaaggaaagt tgtcccagga ttcatcctaa 2400

 agaaagcaaa agttaattca actgatccac caatggaatt agatgggtag 2450

 agttgggttc ttgagtttta ccaccactta gttcccactg aattttgtaa 2500

 cttcctgtgt ttgcatcctc tgttcctatt ctgcccttgc tctgtgtcat 2550

 ctcagtcatt tgacttagaa agtgcccttc aaaaggaccc tgttcactgc 2600

 tgcacttttc aatgaattaa aatttatttc tgttctaaaa aaaaaaaaaa 2650

 a 2651

<210> 2554
<211> 134
<212> PRT
<213> Homo sapien

<400> 2554
 Met Lys Trp Leu Arg Asn Ile Ser Ser Glu Glu Leu Pro Arg Val
   1               5                  10                  15

 Gly Glu Gly Cys Leu Phe Arg Gly Pro Ser Glu Asp Arg Ala Leu
                  20                  25                  30

 Glu Gln Thr Ser Gly Arg Ala Val Pro Gly Ile Lys Glu Arg Ser
                  35                  40                  45

 Ala Cys Pro Ala Gly Ser Leu Asn Leu Ser Ser Met Tyr Glu Val
                  50                  55                  60

 Ile Gly Ser Ile Cys Ile Phe Leu Ser Phe Ser Ser Phe Val Leu
                  65                  70                  75

 Arg Trp Lys Ile Phe Leu Gln Leu Met Gln Ser Ile Asn Tyr Phe
                  80                  85                  90

 Thr Leu Pro Ser Pro Leu Leu Asp Gly Phe Phe Leu Ser Phe Gly
                  95                 100                 105

 Val Leu Tyr Asp Tyr Gln Tyr Ser Pro Val Lys Ile Lys Ser Ile
                 110                 115                 120

 Gln Val Ser Ser Leu Leu Arg Thr Pro Lys Cys Phe Tyr Phe
                 125                 130

<210> 2555
<211> 4774
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3350-3629
<223> Unknown base

<400> 2555
 gctcgagcgg cgcagtgtgc tgaagaattt ttttttactg gaataaaaac 50

 cttctagttt gaacaaaaat atacaacagg gaggacaaca cagagtgcca 100

 actcctccag gttcaggaag aactttctaa ctgcttacct cctagtaaca 150

 gcagttctga cagcccaatc ccaaaagacc cacacatcca gcagacgtga 200

 agccaacagg atgtgtatgt gaggggaggg ccaacgataa gcaggatgtc 250

 tatatatttg tattgacagt tgtcttatct cattccatag ttctccaaat 300

 ttgattataa atcccttgaa ggcagagacc tcattagtat ctaaactcca 350

 gccaccggcc ttcaaggcac ggctttttat tccttcggct ggtcggcctc 400

 tcgcccttca gctacctgtg cgtccctccg tcccgtcccg tcccggggtc 450

 accccggagc ctgtccgcta tgcggctcct gcctctagcc ccaggtcggc 500

 tccggcgggg cagcccccgc cacctgccct cctgcagccc agcgctgcta 550

 ctgctggtgc tgggcggctg cctgggggtc ttcggggtgg ctgcgggaac 600

 ccggaggccc aacgtggtgc tgctcctcac ggacgaccag gacgaagtgc 650

 tcggcggcat gacaccacta aagaaaacca aagctctcat cggagagatg 700

 gggatgactt tttccagtgc ttatgtgcca agtgctctct gctgccccag 750

 cagagccagt atcctgacag gaaagtaccc acataatcat cacgttgtga 800

 acaacactct ggaggggaac tgcagtagta agtcctggca gaagatccaa 850

 gaaccaaata ctttcccagc aattctcaga tcaatgtgtg gttatcagac 900

 cttttttgca gggaaatatt taaatgagta cggagcccca gatgcaggtg 950

 gactagaaca cgttcctctg ggttggagtt actggtatgc cttggaaaag 1000

 aattctaagt attataatta caccctgtct atcaatggga aggcacggaa 1050

 gcatggtgaa aactatagtg tggactacct gacagatgtt ttggctaatg 1100

 tctccttgga ctttctggac tacaagtcca actttgagcc cttcttcatg 1150

 atgatcgcca ctccagcgcc tcattcgcct tggacagctg cacctcagta 1200

 ccagaaggct ttccagaatg tctttgcacc aagaaacaag aacttcaaca 1250

 tccatggaac gaacaagcac tggttaatta ggcaagccaa gactccaatg 1300

 actaattctt caatacagtt tttagataat gcatttagga aaaggtggca 1350

 aactctcctc tcagttgatg accttgtgga gaaactggtc aagaggctgg 1400

 agttcactgg ggagctcaac aacacttaca tcttctatac ctcagacaat 1450

 ggctatcaca caggacagtt ttccttgcca atagacaaga gacagctgta 1500

 tgagtttgat atcaaagttc cactgttggt tcgaggacct gggatcaaac 1550

 caaatcagac aagcaagatg ctggttgcca acattgactt gggtcctact 1600

 attttggaca ttgctggcta cgacctaaat aagacacaga tggatgggat 1650

 gtccttattg cccattttga gaggtgccag taacttgacc tggcgatcag 1700

 atgtcctggt ggaataccaa ggagaaggcc gtaacgtcac tgacccaaca 1750

 tgcccttccc tgagtcctgg cgtatctcaa tgcttcccag actgtgtatg 1800

 tgaagatgct tataacaata cctatgcctg tgtgaggaca atgtcagcat 1850

 tgtggaattt gcagtattgc gagtttgatg accaggaggt gtttgtagaa 1900

 gtctataatc tgactgcaga cccagaccag atcactaaca ttgctaaaac 1950

 catagaccca gagcttttag gaaagatgaa ctatcggtta atgatgttac 2000

 agtcctgttc tgggccaacc tgtcgcactc caggggtttt tgaccccgga 2050

 tacaggtttg acccccgtct catgttcagc aatcgcggca gtgtcaggac 2100

 tcgaagattt tccaaacatc ttctgtagcg acctcacaca gcctctgcag 2150

 atggatccct gcacgcctct ttctgatgaa gtgattgtag taggtgtctg 2200

 tagctagtct tcaagaccac acctggaaga gtttctgggc tggctttaag 2250

 tcctgtttga aaaagcaacc cagtcagctg acttcctcgt gcaatgtgtt 2300

 aaactgtgaa ctctgcccat gtgtcaggag tggctgtctc tggtctcttc 2350

 ctttagctga caaggacact cctgaggtct ttgttctcac tgtatttttt 2400

 ttatcctggg gccacagttc ttgattattc ctcttgtggt taaagactga 2450

 atttgtaaac ccattcagat aaatggcagt actttaggac acacacaaac 2500

 acacagatac accttttgat atgtaagctt gacctaaagt caaaggacct 2550

 gtgtagcatt tcagattgag cacttcacta tcaaaaatac taacatcaca 2600

 tggcttgaag agtaaccatc agagctgaat catccaagta agaacaagta 2650

 ccattgttga ttgataagta gagatacatt ttttatgatg ttcatcacag 2700

 tgtggtaagg ttgcaaattc aaaacatgtc acccaagctc tgttcatgtt 2750

 tttgtgaatt ctaggctggt gctgcactga aatagagcag taagcttgtg 2800

 ataaaggcca attccaggta gctcttgaag gtgatagcca tctactttcc 2850

 agtggctgcc aaccacaggg agtgccagtt aacactggaa ggattaaggc 2900

 aaggtccctt ctcttgagac tcccctctga gatctgaaaa atgaagtggc 2950

 ttaggaacat cagcagtgaa gaactgccaa gagttggtga aggttgtctc 3000

 ttccgagggc cttctgaaga cagggctctt gaacagacaa gtggaagggc 3050

 tgtaccaggg ataaaggaaa gaagtgcctg tccagcaggg agcttgaatt 3100

 taagttccat gtatgaagtc attggctcta tctgcatttt tctgtcattc 3150

 tcttcatttg ttttaaggtg gaaaattttc ttacagttga tgcaaagtat 3200

 caactacttt accctacctt ctcccctttt agatgggttc ttcctgagtt 3250

 ttggagtctt gtatgattat cagtattccc ctgtcaaaat caaatctatt 3300

 caggtttctt cactgttgag aacacctaaa tgtttttatt tttgagaagn 3350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt aagaacacct aaatttttat 3650

 gtttcttggc tcaaaaacca gttccatttc taatgttgtc ctcacaagaa 3700

 ggctaattgg tggtgagaca gcaggggagg aggaagagct gtggtttgta 3750

 acttgttcaa ctcaggcaat aagcgatttt agctttattt aaagtcttct 3800

 gtccagcttt aagcactttg taagacatgg ctgaaagtag cttttctatc 3850

 agaattgcag atagtcatgt tgggctaaca gtcaattgga tatattcctt 3900

 tacctcacat gaccccagca actgtggtgg tatctagagg tgaaacaggc 3950

 aagtgaaatg gacacctctg ctgtgaatgt tttagagaag gaaattcaaa 4000

 aaatgttgta actgaaagca ctgttgaata tgggtatcgg ctttcttttt 4050

 cactttgact cttaacatta tcagtcaact tccacattaa tgaaagttga 4100

 ccatagttat ttccaaataa aaagaaacca actcttacca ggtcttggac 4150

 tgtgatgtca tattattcag ttttatgctt gttcctgagc agaactcata 4200

 agagtgacat agtcagctgc tgacggcacc tcagccacgc cactcttact 4250

 cagttcagtg ggtgtgcttg cgtggtagga tgtggtgcag ccctctctac 4300

 gctcttctat ttttggtata tttcctatct aaccttcaaa tagcttccaa 4350

 ttcttttttt cttggactgg cttcattctg aatttgtgct aaaataatct 4400

 ttcataaaga gacctcagtt tatagcgtaa cagactacac aatgcactga 4450

 tgttttcata atgtttaagg gacccactgc aagaaggttg ctgcctcctt 4500

 ttaattgtat tcatttagat tttgattttc catgttaaga aggtgaggtc 4550

 catgttggtg cccttcagag tagagaacca tgtaaacatt aggaatgaac 4600

 agaggcctta ggaatgaata gagagtttgc cttatacaat ttcctgttac 4650

 aaagctctcc ctctcatgca aagtagggaa caccttttga gcatctttga 4700

 atttgacaaa tggtgctgtt gcaaacactt tttttttgag atgaagtctc 4750

 gcggttgtca cccgggctgg agtg 4774

<210> 2556
<211> 552
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3350-3629
<223> Unknown amino acid

<400> 2556
 Met Arg Leu Leu Pro Leu Ala Pro Gly Arg Leu Arg Arg Gly Ser
   1               5                  10                  15

 Pro Arg His Leu Pro Ser Cys Ser Pro Ala Leu Leu Leu Leu Val
                  20                  25                  30

 Leu Gly Gly Cys Leu Gly Val Phe Gly Val Ala Ala Gly Thr Arg
                  35                  40                  45

 Arg Pro Asn Val Val Leu Leu Leu Thr Asp Asp Gln Asp Glu Val
                  50                  55                  60

 Leu Gly Gly Met Thr Pro Leu Lys Lys Thr Lys Ala Leu Ile Gly
                  65                  70                  75

 Glu Met Gly Met Thr Phe Ser Ser Ala Tyr Val Pro Ser Ala Leu
                  80                  85                  90

 Cys Cys Pro Ser Arg Ala Ser Ile Leu Thr Gly Lys Tyr Pro His
                  95                 100                 105

 Asn His His Val Val Asn Asn Thr Leu Glu Gly Asn Cys Ser Ser
                 110                 115                 120

 Lys Ser Trp Gln Lys Ile Gln Glu Pro Asn Thr Phe Pro Ala Ile
                 125                 130                 135

 Leu Arg Ser Met Cys Gly Tyr Gln Thr Phe Phe Ala Gly Lys Tyr
                 140                 145                 150

 Leu Asn Glu Tyr Gly Ala Pro Asp Ala Gly Gly Leu Glu His Val
                 155                 160                 165

 Pro Leu Gly Trp Ser Tyr Trp Tyr Ala Leu Glu Lys Asn Ser Lys
                 170                 175                 180

 Tyr Tyr Asn Tyr Thr Leu Ser Ile Asn Gly Lys Ala Arg Lys His
                 185                 190                 195

 Gly Glu Asn Tyr Ser Val Asp Tyr Leu Thr Asp Val Leu Ala Asn
                 200                 205                 210

 Val Ser Leu Asp Phe Leu Asp Tyr Lys Ser Asn Phe Glu Pro Phe
                 215                 220                 225

 Phe Met Met Ile Ala Thr Pro Ala Pro His Ser Pro Trp Thr Ala
                 230                 235                 240

 Ala Pro Gln Tyr Gln Lys Ala Phe Gln Asn Val Phe Ala Pro Arg
                 245                 250                 255

 Asn Lys Asn Phe Asn Ile His Gly Thr Asn Lys His Trp Leu Ile
                 260                 265                 270

 Arg Gln Ala Lys Thr Pro Met Thr Asn Ser Ser Ile Gln Phe Leu
                 275                 280                 285

 Asp Asn Ala Phe Arg Lys Arg Trp Gln Thr Leu Leu Ser Val Asp
                 290                 295                 300

 Asp Leu Val Glu Lys Leu Val Lys Arg Leu Glu Phe Thr Gly Glu
                 305                 310                 315

 Leu Asn Asn Thr Tyr Ile Phe Tyr Thr Ser Asp Asn Gly Tyr His
                 320                 325                 330

 Thr Gly Gln Phe Ser Leu Pro Ile Asp Lys Arg Gln Leu Tyr Glu
                 335                 340                 345

 Phe Asp Ile Lys Val Pro Leu Leu Val Arg Gly Pro Gly Ile Lys
                 350                 355                 360

 Pro Asn Gln Thr Ser Lys Met Leu Val Ala Asn Ile Asp Leu Gly
                 365                 370                 375

 Pro Thr Ile Leu Asp Ile Ala Gly Tyr Asp Leu Asn Lys Thr Gln
                 380                 385                 390

 Met Asp Gly Met Ser Leu Leu Pro Ile Leu Arg Gly Ala Ser Asn
                 395                 400                 405

 Leu Thr Trp Arg Ser Asp Val Leu Val Glu Tyr Gln Gly Glu Gly
                 410                 415                 420

 Arg Asn Val Thr Asp Pro Thr Cys Pro Ser Leu Ser Pro Gly Val
                 425                 430                 435

 Ser Gln Cys Phe Pro Asp Cys Val Cys Glu Asp Ala Tyr Asn Asn
                 440                 445                 450

 Thr Tyr Ala Cys Val Arg Thr Met Ser Ala Leu Trp Asn Leu Gln
                 455                 460                 465

 Tyr Cys Glu Phe Asp Asp Gln Glu Val Phe Val Glu Val Tyr Asn
                 470                 475                 480

 Leu Thr Ala Asp Pro Asp Gln Ile Thr Asn Ile Ala Lys Thr Ile
                 485                 490                 495

 Asp Pro Glu Leu Leu Gly Lys Met Asn Tyr Arg Leu Met Met Leu
                 500                 505                 510

 Gln Ser Cys Ser Gly Pro Thr Cys Arg Thr Pro Gly Val Phe Asp
                 515                 520                 525

 Pro Gly Tyr Arg Phe Asp Pro Arg Leu Met Phe Ser Asn Arg Gly
                 530                 535                 540

 Ser Val Arg Thr Arg Arg Phe Ser Lys His Leu Leu
                 545                 550

<210> 2557
<211> 3911
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 432, 847, 904, 1401, 1600, 1631
<223> Unknown base

<400> 2557
 aaaccctgtt cttgggtggg tgtgggtata atactaagtt gagatgatat 50

 catttacggg ggaaggcgct ttgtgaagta ggccttattt ctcttgtcct 100

 ttcgtacagg gaggaatttg aagtagatag aaaccgacct ggattactcc 150

 ggtctgaact cagatcacgt aggactttaa tcgttgaaca aacgaacctt 200

 taatagcggc tgcaccattg ggatgtcctg atccaacatc gaggtcgtaa 250

 accctattgt tgatatggac tctagaatag gattgcgctg ttatccctag 300

 ggtaacttgt tccgttggtc aagttattgg atcaattgag tatagtagtt 350

 cgctctgact ggtgaagtct tagcatgtac tgctcggagg ttgggttctg 400

 ctccgaggtc gccccaaccg aaatttttaa tncaggtttg gtagtttagg 450

 gcctgtgggt ttgttaggta ctgtttgcat taataaatta aagctccata 500

 gggtcttctc gtcttgctgt gtcatgcccg cctcttcacg ggcaggtcaa 550

 tttcactggt taaaagtaag agacagctgt accctcgtgg agccattcat 600

 acaggtccct agttaaggaa caagtgatta tgctaccttt gcacggttag 650

 ggtaccgcgg ccgttaaaca tgtgtcactg ggcaggcggt gcccctaata 700

 ctggtgatgc tagaggtgat gtttttggta aacaggcggg gtaagatttg 750

 ccgagttcct tttacttttt ttaacctttc cttatgagca tgcctgtgtt 800

 gggttgacag tgagggtaat aatgacttgt tggttgattg tagatantgg 850

 gctgttaatt gtcagttcag tgttttaatc tgacgcaggc ttatgcggag 900

 gagnatgttt tcatgttact tatactaaca ttagttcttc tatagggtga 950

 tagattggtc caattgggtg tgaggagttc agttatatgt ttgggatttt 1000

 ttaggtagtg ggtgttgagc ttgaacgctt tcttaattgg tggctgcttt 1050

 taggcctact atgggtgtta aattttttac tctctctaca aggttttttc 1100

 ctagtgtcca aagagctgtt cctctttgga ctaatagtta aatttacaag 1150

 gggatttaga gggttctgtg ggcaaattta aagttgaact aagattctat 1200

 cttggacaac cagctatcac caggctcggt aggtttgtcg cctctaccta 1250

 taaatcttcc cactattttg ctaaaagagc acacccgtct atgtacggaa 1300

 ttccgggaag aacttaagcg acaatcttga acaccccttc tcatgtgatg 1350

 tgaaatgaaa ccatttggaa aagtttcttc tagccagtaa tagatttttt 1400

 ntttaattgc tctgccttgt gccgagagat gttcttttaa gatgaatctt 1450

 ttgatgtctg ataccaccaa atataggtgg tagggagagt tggaggctgg 1500

 ccctttgagc aggccattag cttacttgct gggcatttcc gatagcttat 1550

 tgcctaccct tttgctggaa acaagctgat ttgaaaaacc aaatctatgn 1600

 agactgcagc taaggatttt atcggtagac ntaagagctt ttgtccttgt 1650

 ggatatttta gtggaaccac atcagtctca atactgtcat tttacactga 1700

 ctcagagcag ctgacttcat tccttgccac gatatatatt taaggcaggc 1750

 attgtaacag acataaagac aacttatctg tttcagcagg aaggattcag 1800

 tttatgaact ctcagaccag atcatgttga acaaggagac tttgatgtgt 1850

 gtcatgagga aactcattct ttacttccca gtcaatttaa aggccagcta 1900

 tcctgagcta ctcgaatgaa tgcactggtt aaacattgga aatagtttgt 1950

 ttatatcctt gtctctctct aggccaattg tgattacatg actcgactct 2000

 acatctcgtc aaacaaggcc taggtctggt tgctgtagac tgctcgccct 2050

 caacaaataa aatctggttg actagcctcc ttgtatatac aactattatt 2100

 tgttaagaag aaattatcgt caattttcta ctaccttcca attgtcagct 2150

 ctttttttcc tctctggttt ttcctacact ttacagaaaa agacattgat 2200

 ctatactgcc attccctcta atcctgccat actcagtcaa aaggaatgac 2250

 ttaagatgaa gatgatcatc tgctcgagtc aaaatataca ttgtatataa 2300

 gaattggtga ttagaaaagc aaaaaaccta aaacttaaat ctaggagtct 2350

 gtatactgtc tccatgtctc catgcctcag atctcatcta aatctttgaa 2400

 cagcaccatt caaccaatct gaggccttga cttgcttgta agatgattct 2450

 cagagatcgg ctgagttaaa aaagatgacg acttgattac caaagaaagt 2500

 agggccaact ttgacaaatc tggctctgct gaccctgtca ctcccagatg 2550

 tagcatagac tcctaaacag aacctcaagt ctgattgagg ataaggcctt 2600

 ctcctgagct gaaagttctt tggcagatga gcaagaaact gaaagctgat 2650

 gtacctgact ggctctgtaa gatcagaaaa ctgtatccag aataagccct 2700

 atggattaac ccctgagtac ccagagtaaa aactaattta cagaacttcc 2750

 ttattgatct gctggttctt ccagatcata ttctggctat tggtatggct 2800

 ggcctttctg aaggtaccct gcttgtctat tttcctgact cagctcttgc 2850

 ctgccttttt cacatgttgc tgcaattaga ctcaccgtga ggactacagt 2900

 caatttcagt ctatcttgtg cccaatacaa caaggatttt taatagtaac 2950

 aacccacacc tcacccacta ggactcaatg ttcacaacag gaaggaccat 3000

 tgctgcatac tccttgacca gcaacttttt tgaagatatt tttaagtgca 3050

 gagtaggcct ctattcctgt atgtaattgt tcattttcag cacctggaac 3100

 ctcatctatc gggtctggaa ggaatacagc agttcgaaag ccgcgtccat 3150

 ttctctcctt cagtagtgca gaaatgagtc cgattcacca gtacacacag 3200

 aactgtacca gttcaaccta gcaaaagaag aaaagtttcc actgtactta 3250

 aaatttacag ctgactcaaa ttgcctcaca gaattacttg atgtagaagg 3300

 ctagtcgtct tacttcggat cagcaggaca gttgggctct cagactcatg 3350

 accactgagt ttgcttgtgt tgaaactgtg gtttcatcca acatatgcta 3400

 ttggacatga ttattattcc attcaaatgg attacagact tcttgaggac 3450

 aggacaaact tatctctcat ggtgtttttt tagaatactt ttataaccaa 3500

 ggaagaaacc atgccagctg ttaccattca acttcttaag cagagattaa 3550

 gctttttcat atctgttctt atcctggaca tcagtagttt ttaattgccc 3600

 agcatccgtt ccatcttgta acaactccct gatgtttctt aaaaccacct 3650

 cttcctattt tcagtctgtg gtttggacag tctgacccaa ccttgagctt 3700

 tgtgggtgaa catgtaattc agacctcatc aatcagcaaa tccatctgaa 3750

 ctgtggagga gaagctctct ttactgaggg tgctttagct ttgtaggatg 3800

 aaaacctcaa actaacaggg cctaccatgt agagaatgaa gccagtgcag 3850

 gggaaagcag agccaaaata tggagagact tgaatcctga tgacagcgtt 3900

 tgtgcccctg g 3911

<210> 2558
<211> 1344
<212> DNA
<213> Homo sapien

<400> 2558
 gtctagttta tacccgggtc caggactggg gcatggccac tcccctggcc 50

 tgcaccccta cactgctcta cagccccacc tgccctgtag ccctcagtat 100

 ctcactcacc cagctcaccc tgcccacccc atgcctcaca tgccccggcc 150

 tgccgtcttc cctgtgccca gctctgcata cccacagggt gtgcatcctg 200

 cattcctagg ggctcagtac ccttattcag tgactcctcc ctcacttgct 250

 gccactgctg tgtctttccc cgttccttcc atggcaccca tcacagtaca 300

 tccctaccac acagagccag ggcttccact gcccaccagt gtggcctgtg 350

 agttgtgggg ccagggaaca gtgagcagtg tccatccagc atccacgttt 400

 ccagccatcc aaggtgcctc actgcctgcc ctgaccacac agcccagccc 450

 tctggtgagc ggaggttttc caccgcccga ggaggagaca cacagtcagc 500

 cagtcaatcc ccacagcctg caccacctgc atgctgccta ccgtgtcgga 550

 atgctggcac tggagatgct gggtcgccgg gcacacaacg atcaccccaa 600

 caacttctcc cgctcccccc cctacactga tgatgtcaaa tggttgctgg 650

 ggctggcagc aaagctggga gtgaactacg tgcaccagtt ctgtgtgggg 700

 gcagccaagg gggtgctgag cccgtttgtg ctgcaggaga tcgtcatgga 750

 gacgctgcag cggctgagtc ccgctcatgc ccacaaccac ctgcgtgccc 800

 cggccttcca ccaactggtg cagcgctgcc agcaggcata catgcagtac 850

 atccaccacc gcttgattca cctgactcct gcggactacg acgactttgt 900

 gaatgcgatc cggagtgccc gcagcgcctt ctgcctgacg cccatgggca 950

 tgatgcagtt caacgacatc ctacagaacc tcaagcgcag caaacagacc 1000

 aaggagctgt ggcagcgggt ctcactcgag atggccacct tctccccctg 1050

 agtctttcac ccttagggtc ctatacaggg acccaggcct gtggctatgg 1100

 gggcccctca cacaggggga gtgaaacttg gctggacaga tcatcctcac 1150

 tcagttccct ggtagcacag actgacagct gctcttgggc tatagcttgg 1200

 ggccaagatg tctcacaccc tagaagccta gggctggggg agacagccct 1250

 gtctgggagg gggcgttggg tggcctctgg tatttatttg gcatttataa 1300

 atatataaac tcctttttta ctctagtcga aaaaaaaaaa aaaa 1344

<210> 2559
<211> 6578
<212> DNA
<213> Homo sapien

<400> 2559
 ggtgaacagc tcaaatccat tttttacatc acagaccaaa gccaatggga 50

 atcctgcttg ttcggcccag ttgcagcatg tctcgccacc catttttcca 100

 gctcatttag caagtgtgtc aactccattg ttgtcctcaa tggaaagtgt 150

 cataaatcca aatataactt ctcaggataa aaatgaacaa ggtggtatgt 200

 tatgttccca aatggaaaat ttacctagta ctgccttgcc agcacaaatg 250

 gaagatctaa ccaaaacagt tctgcctttg aatattgaca gtggctcaga 300

 tcctttcctt cctttacctg cagaaagtag ttcaatgtct ctcttccctt 350

 caccagcaga tagtgggact aattctgttt tttcccaact ggaaaataat 400

 acaaatcatt attcctcaca gattgaagga aacactaatt cctcctttct 450

 aaaggggggt aatggtgaaa atgcagtttt tccttcacaa gtgaatgttg 500

 caaataactt cagtagcacc aatgcccaac agtctgcacc tgaaaaagtt 550

 aaaaaagacc gtgggcgggg cccaaatggg aaggaaagaa aacctaagca 600

 caacaaaagg gctaaatggc ctgcaattat cagagatggg aaatttatct 650

 gtagcaggtg ttacagggct tttactaatc ccagatcact gggtgggcac 700

 ttatccaagc gatcttactg taaaccactg gatggagccg aaattgctca 750

 agaacttcta cagagtaatg gacagccttc tcttcttgcc agcatgattc 800

 tctccacaaa tgcagtaaat ttgcagcagc cacaacaatc taccttcaat 850

 ccagaagcat gttttaaaga tccatcattt ctacagcttc ttgctgaaaa 900

 tcgctcgcca gcatttttac caaatacatt tcctcgatct ggtgtgacta 950

 actttaatac cagtgtcagt caagaaggta gtgaaattat taaacaggct 1000

 ttggaaactg ctggcattcc cagtacattt gagggtgccg aaatgctttc 1050

 tcatgtttca acaggttgtg tctctgatgc atcacaagta aatgcaacgg 1100

 tgatgccaaa tccaactgta ccacccctgt tgcacactgt atgccatcca 1150

 aacaccttgc tgaccaacca gaataggacg tcaaactcca aaacttcctc 1200

 cattgaggaa tgtagcagct tgcctgtttt tccaacgaat gacttactac 1250

 tgaagactgt tgaaaatggt ttgtgctcta gttcatttcc taattctggt 1300

 gggccatcac aaaattttac cagtaacagt tctcgtgttt ctgttataag 1350

 tggtcctcag aacacaagat ccagtcattt aaataaaaag ggaaacagtg 1400

 cttctaagag aagaaagaaa gttgctcctc cactaattgc acctaacgct 1450

 tcccaaaact tggtaacaag tgacttaaca acaatgggac tcatagcaaa 1500

 gagtgttgaa atcccaacta ctaaccttca ttcaaatgta attccaactt 1550

 gtgaacctca gagtttggtg gaaaatctaa cacagaaatt aaataatgtt 1600

 aacaatcagt tatttatgac tgatgtaaaa gagaatttca aaaccagtct 1650

 tgagtcccat acagtgttag cccctttaac attaaaaact gaaaatggtg 1700

 attcccaaat gatggctttg aattcatgca caacttcagt aaattctgat 1750

 ttgcagattt ctgaagacaa tgttatacaa aactttgaaa agactcttga 1800

 aattattaaa actgctatga attctcaaat acttgaggta aaaagtggat 1850

 ctcagggtgc tggtgaaact tcacaaaatg ctcaaataaa ttataacatt 1900

 cagcttcctt cagtaaacac tgtgcaaaat aacaaattac ccgattcttc 1950

 tccgttttcc tcctttataa gtgtcatgcc aacaaaaagt aacattcctc 2000

 agtctgaagt atcacataag gaggatcaaa tacaggaaat tttagaaggc 2050

 ttacagaaat taaaattaga aaatgaccta tccactccag catcccaatg 2100

 tgtactgata aatacatcag tgacactgac tcccacgcct gttaaatcaa 2150

 ctgcagatat cacagttatt cagccagttt ctgaaatgat aaacattcaa 2200

 tttaatgaca aagttaataa accctttgtg tgtcaaaacc aaggctgtaa 2250

 ctacagtgct atgacaaagg atgcactatt taagcactat ggtaaaattc 2300

 atcaatacac tccagaaatg attcttgaaa ttaagaagaa tcaattgaaa 2350

 tttgctccct ttaaatgtgt agtacctaca tgtacaaaaa catttacaag 2400

 aaattctaac ctccgggcac actgtcagtt ggtgcatcat tttacaactg 2450

 aagaaatggt aaagttaaaa attaaaaggc cttatggaag aaaatctcag 2500

 agtgaaaatg tgccggcctc acgaagtaca caagtgaaaa aacagctagc 2550

 tatgacagag gaaaataaaa aggaatctca gcctgcttta gaattgagag 2600

 cagagaccca aaatacccac agtaatgtag cagtgatccc agaaaaacaa 2650

 cttatagaaa aaaaaagtcc tgacaaaaca gaaagttctt tacaagtgat 2700

 tacagttact tcagaacaat gtaatacaaa tgcactcaca aacacacaaa 2750

 ccaaaggacg gaagattagg aggcataaaa aagaaaagga ggagaaaaaa 2800

 cgaaagaagc cagtttccca atcccttgag tttccaacaa gatacagtcc 2850

 ttacagacct tatcgatgtg ttcaccaggg atgctttgct gcctttacga 2900

 tacagcaaaa tttgattctc cattaccagg ctgtacacaa atcagatcta 2950

 cctgcatttt cagcagaggt cgaagaggaa agtgaagctg gtaaagaaag 3000

 tgaagaaact gaaactaaac aaactttgaa agaatttcga tgtcaggtaa 3050

 gtgactgttc tcgaattttc caagcaatta ctggcctaat acaacactac 3100

 atgaaacttc atgaaatgac tcctgaagaa attgaaagta tgactgcttc 3150

 agtggatgtt gggaagtttc catgtgacca gttagagtgt aaatcttcat 3200

 ttactacata tttgaactat gttgttcatc tagaggcaga ccacgggatt 3250

 ggactaaggg caagtaaaac agaagaagat ggtgtataca aatgtgattg 3300

 tgaaggctgt gaccgtatat atgcaacccg gtcgaatctc ctccgacaca 3350

 tttttaataa gcataatgac aaacataagg ctcatttgat tcgtccaaga 3400

 agattaacac caggccagga aaatatgtca agcaaggcaa accaagaaaa 3450

 atcaaagtct aaacatcggg ggacgaagca cagcagatgt ggaaaggaag 3500

 gaataaaaat gcccaagacc aaacgaaaga aaaaaaataa tttagaaaac 3550

 aagaatgcaa agattgtgca gattgaagaa aataagcctt attctctgaa 3600

 acgtgggaag catgtatatt ctataaaggc tagaaatgat gccctgtctg 3650

 agtgtacaag cagatttgta acccagtatc catgtatgat aaagggatgt 3700

 acttcagttg ttacaagtga aagcaatata attagacatt ataagtgcca 3750

 taaattatct aaggcattta catcacaaca ccgaaatctt cttattgtat 3800

 tcaaacggtg ttgcaactca caagtaaagg aaacgtctga gcaagaaggt 3850

 gctaagaatg atgtgaaaga ttctgacacg tgtgtatcag agagcaatga 3900

 taattcaaga acaacagcta cagtttcaca aaaggaagtt gaaaaaaatg 3950

 aaaaagatga aatggatgaa ctaacagaat tgtttattac aaaattaata 4000

 aatgaagata gcacaagtgt agagacccaa gctaatactt cttcaaatgt 4050

 aagtaatgat tttcaggaag ataacctctg ccagtcagaa agacaaaaag 4100

 caagtaattt gaagagagtt aataaggaaa aaaatgtctc acaaaataaa 4150

 aaaaggaaag ttgaaaaagc tgaaccagca tcagcagctg agttaagtag 4200

 cgtgcgtaaa gaagaagaaa ctgctgttgc cattcaaacc attgaggagc 4250

 atcctgcatc ttttgactgg agctctttta agccaatggg atttgaagta 4300

 tcatttctga agtttcttga ggagtctgca gtgaagcaga agaaaaatac 4350

 tgacaaagac catccgaata ctggaaacaa aaaaggatcc cattcaaatt 4400

 caagaaaaaa tattgataag actgctgtga ctagtggaaa tcatgtatgt 4450

 ccttgtaaag aaagcgaaac gtttgtacag tttgccaatc catcacagct 4500

 tcagtgcagt gataatgtaa aaattgtttt agacaagaat cttaaagatt 4550

 gcactgagct tgtcttaaag caacttcagg aaatgaaacc taccgtcagt 4600

 ctgaaaaaac ttgaagtaca ttcaaatgat ccagatatgt ctgttatgaa 4650

 agatatcagt ataggtaaag ccacaggcag aggtcagtac tgataattaa 4700

 tgtagtataa atacatcatt taccatttta ttttaaatag gaagccatca 4750

 agcatgctag aattgtgaaa ctttcattat atttttttgt tgttgacatg 4800

 aattaacctg gccaaaaaca aaaaagaaaa aaaaaacatg acatttgtca 4850

 tgtaaaactt ttttttatcc ctatgggact tgaggaacag aatcagtact 4900

 tcagttattg taaatagtga gctaaacctc aaatttctat cacccagttg 4950

 cccttttcat gaactaaaca attatctgtg tgattggtat gtttcaccag 5000

 gtcactgctc atgtataaca gtactcttta tttgtagata ccttttttgt 5050

 atatatttat tattgtaaat catgtgctgc caccagcagt ctgtaagtct 5100

 aaactattaa atgacacatt tatatttgga attttaattt ttaactaagc 5150

 gatcaagttt tttaaattgt tcttttattg ttttaaatta agaacttttt 5200

 gaactaaaac cagaaactct gccatagttc attgattttt acatgaaaca 5250

 tttatttaca agatgatatc aagattactt ttcacaaaat aggcacatta 5300

 tatcaacact ttgctctgct ttgtaaattt gccatccagg attttggggt 5350

 ggtattcatg tgaaattaaa gcagattctc tagcagtttc ctatagctac 5400

 agtttttttt tttcattgct tctaattgga tatagttact atgagtccat 5450

 gaaatacaat ggaaatgtga ataaagaatt tactacattg aagattttaa 5500

 acatttggta ttaaaaaaaa atcctttgtg aatgtgatag aaaactagta 5550

 gtgtggagca gtgtaaatat ttgaggtggt gatttgtgaa gtagcccagt 5600

 attgccttaa ataaaatcac atttcatttc ttgttttata catgtgatct 5650

 tataaagatt ttttgttttg ttttgttttc cattttctga gatttataga 5700

 ttggtgtata gctttaaact gtataaagtt ttgtggaaag atttttttaa 5750

 acatttttat aaatcttaaa attgatatca tcaaagtgag cccatcttgt 5800

 gtttataaaa tacaagagtc cttaacattt ataattacat agataaaaca 5850

 ctttctataa ggaagttgga tgttttgatt ttactgttta tagatgttag 5900

 attgtacaga tttgtctgta tttctcacca tatctaatga tacttttttc 5950

 attagattgg tcttcaagaa cagtattagt tataattatt ttggttattc 6000

 agtatatagt tagctcttac agtttagctt tattcaccat atttatactg 6050

 tggattcaca gcgagaggta gaggttattc caggagagtt gatgaccttc 6100

 atttaaagtc caactaaaat cagtagtaga aacataagaa aacatctttg 6150

 caatatttac ttttgtttct gtttgccgta aatagtaaca ttgttttttt 6200

 ttattttgtg tttgttataa aacagttgca ttcacaatat tattggcctg 6250

 agatattgat gatattgtga tggtatgaaa atgtgtacat tccctgtgca 6300

 acatcagatt tgcaggaaaa atgaagcact tactgaaatc gctggtactc 6350

 tgaataaata agcatggtca aggagtgaac tattttcttt tggaaatttc 6400

 tttttaattt ttattattaa agtattttat ttttagggcc ttttgggttt 6450

 tattgaatag ttcatttcac ctgtttaaga cttactacca ataagcataa 6500

 aacctgacac gttaaaatcc ctgccctttg gtgagcccac tgttatttat 6550

 taaaataaaa gttattttat gggtgatt 6578

<210> 2560
<211> 1563
<212> PRT
<213> Homo sapien

<400> 2560
 Val Asn Ser Ser Asn Pro Phe Phe Thr Ser Gln Thr Lys Ala Asn
   1               5                  10                  15

 Gly Asn Pro Ala Cys Ser Ala Gln Leu Gln His Val Ser Pro Pro
                  20                  25                  30

 Ile Phe Pro Ala His Leu Ala Ser Val Ser Thr Pro Leu Leu Ser
                  35                  40                  45

 Ser Met Glu Ser Val Ile Asn Pro Asn Ile Thr Ser Gln Asp Lys
                  50                  55                  60

 Asn Glu Gln Gly Gly Met Leu Cys Ser Gln Met Glu Asn Leu Pro
                  65                  70                  75

 Ser Thr Ala Leu Pro Ala Gln Met Glu Asp Leu Thr Lys Thr Val
                  80                  85                  90

 Leu Pro Leu Asn Ile Asp Ser Gly Ser Asp Pro Phe Leu Pro Leu
                  95                 100                 105

 Pro Ala Glu Ser Ser Ser Met Ser Leu Phe Pro Ser Pro Ala Asp
                 110                 115                 120

 Ser Gly Thr Asn Ser Val Phe Ser Gln Leu Glu Asn Asn Thr Asn
                 125                 130                 135

 His Tyr Ser Ser Gln Ile Glu Gly Asn Thr Asn Ser Ser Phe Leu
                 140                 145                 150

 Lys Gly Gly Asn Gly Glu Asn Ala Val Phe Pro Ser Gln Val Asn
                 155                 160                 165

 Val Ala Asn Asn Phe Ser Ser Thr Asn Ala Gln Gln Ser Ala Pro
                 170                 175                 180

 Glu Lys Val Lys Lys Asp Arg Gly Arg Gly Pro Asn Gly Lys Glu
                 185                 190                 195

 Arg Lys Pro Lys His Asn Lys Arg Ala Lys Trp Pro Ala Ile Ile
                 200                 205                 210

 Arg Asp Gly Lys Phe Ile Cys Ser Arg Cys Tyr Arg Ala Phe Thr
                 215                 220                 225

 Asn Pro Arg Ser Leu Gly Gly His Leu Ser Lys Arg Ser Tyr Cys
                 230                 235                 240

 Lys Pro Leu Asp Gly Ala Glu Ile Ala Gln Glu Leu Leu Gln Ser
                 245                 250                 255

 Asn Gly Gln Pro Ser Leu Leu Ala Ser Met Ile Leu Ser Thr Asn
                 260                 265                 270

 Ala Val Asn Leu Gln Gln Pro Gln Gln Ser Thr Phe Asn Pro Glu
                 275                 280                 285

 Ala Cys Phe Lys Asp Pro Ser Phe Leu Gln Leu Leu Ala Glu Asn
                 290                 295                 300

 Arg Ser Pro Ala Phe Leu Pro Asn Thr Phe Pro Arg Ser Gly Val
                 305                 310                 315

 Thr Asn Phe Asn Thr Ser Val Ser Gln Glu Gly Ser Glu Ile Ile
                 320                 325                 330

 Lys Gln Ala Leu Glu Thr Ala Gly Ile Pro Ser Thr Phe Glu Gly
                 335                 340                 345

 Ala Glu Met Leu Ser His Val Ser Thr Gly Cys Val Ser Asp Ala
                 350                 355                 360

 Ser Gln Val Asn Ala Thr Val Met Pro Asn Pro Thr Val Pro Pro
                 365                 370                 375

 Leu Leu His Thr Val Cys His Pro Asn Thr Leu Leu Thr Asn Gln
                 380                 385                 390

 Asn Arg Thr Ser Asn Ser Lys Thr Ser Ser Ile Glu Glu Cys Ser
                 395                 400                 405

 Ser Leu Pro Val Phe Pro Thr Asn Asp Leu Leu Leu Lys Thr Val
                 410                 415                 420

 Glu Asn Gly Leu Cys Ser Ser Ser Phe Pro Asn Ser Gly Gly Pro
                 425                 430                 435

 Ser Gln Asn Phe Thr Ser Asn Ser Ser Arg Val Ser Val Ile Ser
                 440                 445                 450

 Gly Pro Gln Asn Thr Arg Ser Ser His Leu Asn Lys Lys Gly Asn
                 455                 460                 465

 Ser Ala Ser Lys Arg Arg Lys Lys Val Ala Pro Pro Leu Ile Ala
                 470                 475                 480

 Pro Asn Ala Ser Gln Asn Leu Val Thr Ser Asp Leu Thr Thr Met
                 485                 490                 495

 Gly Leu Ile Ala Lys Ser Val Glu Ile Pro Thr Thr Asn Leu His
                 500                 505                 510

 Ser Asn Val Ile Pro Thr Cys Glu Pro Gln Ser Leu Val Glu Asn
                 515                 520                 525

 Leu Thr Gln Lys Leu Asn Asn Val Asn Asn Gln Leu Phe Met Thr
                 530                 535                 540

 Asp Val Lys Glu Asn Phe Lys Thr Ser Leu Glu Ser His Thr Val
                 545                 550                 555

 Leu Ala Pro Leu Thr Leu Lys Thr Glu Asn Gly Asp Ser Gln Met
                 560                 565                 570

 Met Ala Leu Asn Ser Cys Thr Thr Ser Val Asn Ser Asp Leu Gln
                 575                 580                 585

 Ile Ser Glu Asp Asn Val Ile Gln Asn Phe Glu Lys Thr Leu Glu
                 590                 595                 600

 Ile Ile Lys Thr Ala Met Asn Ser Gln Ile Leu Glu Val Lys Ser
                 605                 610                 615

 Gly Ser Gln Gly Ala Gly Glu Thr Ser Gln Asn Ala Gln Ile Asn
                 620                 625                 630

 Tyr Asn Ile Gln Leu Pro Ser Val Asn Thr Val Gln Asn Asn Lys
                 635                 640                 645

 Leu Pro Asp Ser Ser Pro Phe Ser Ser Phe Ile Ser Val Met Pro
                 650                 655                 660

 Thr Lys Ser Asn Ile Pro Gln Ser Glu Val Ser His Lys Glu Asp
                 665                 670                 675

 Gln Ile Gln Glu Ile Leu Glu Gly Leu Gln Lys Leu Lys Leu Glu
                 680                 685                 690

 Asn Asp Leu Ser Thr Pro Ala Ser Gln Cys Val Leu Ile Asn Thr
                 695                 700                 705

 Ser Val Thr Leu Thr Pro Thr Pro Val Lys Ser Thr Ala Asp Ile
                 710                 715                 720

 Thr Val Ile Gln Pro Val Ser Glu Met Ile Asn Ile Gln Phe Asn
                 725                 730                 735

 Asp Lys Val Asn Lys Pro Phe Val Cys Gln Asn Gln Gly Cys Asn
                 740                 745                 750

 Tyr Ser Ala Met Thr Lys Asp Ala Leu Phe Lys His Tyr Gly Lys
                 755                 760                 765

 Ile His Gln Tyr Thr Pro Glu Met Ile Leu Glu Ile Lys Lys Asn
                 770                 775                 780

 Gln Leu Lys Phe Ala Pro Phe Lys Cys Val Val Pro Thr Cys Thr
                 785                 790                 795

 Lys Thr Phe Thr Arg Asn Ser Asn Leu Arg Ala His Cys Gln Leu
                 800                 805                 810

 Val His His Phe Thr Thr Glu Glu Met Val Lys Leu Lys Ile Lys
                 815                 820                 825

 Arg Pro Tyr Gly Arg Lys Ser Gln Ser Glu Asn Val Pro Ala Ser
                 830                 835                 840

 Arg Ser Thr Gln Val Lys Lys Gln Leu Ala Met Thr Glu Glu Asn
                 845                 850                 855

 Lys Lys Glu Ser Gln Pro Ala Leu Glu Leu Arg Ala Glu Thr Gln
                 860                 865                 870

 Asn Thr His Ser Asn Val Ala Val Ile Pro Glu Lys Gln Leu Ile
                 875                 880                 885

 Glu Lys Lys Ser Pro Asp Lys Thr Glu Ser Ser Leu Gln Val Ile
                 890                 895                 900

 Thr Val Thr Ser Glu Gln Cys Asn Thr Asn Ala Leu Thr Asn Thr
                 905                 910                 915

 Gln Thr Lys Gly Arg Lys Ile Arg Arg His Lys Lys Glu Lys Glu
                 920                 925                 930

 Glu Lys Lys Arg Lys Lys Pro Val Ser Gln Ser Leu Glu Phe Pro
                 935                 940                 945

 Thr Arg Tyr Ser Pro Tyr Arg Pro Tyr Arg Cys Val His Gln Gly
                 950                 955                 960

 Cys Phe Ala Ala Phe Thr Ile Gln Gln Asn Leu Ile Leu His Tyr
                 965                 970                 975

 Gln Ala Val His Lys Ser Asp Leu Pro Ala Phe Ser Ala Glu Val
                 980                 985                 990

 Glu Glu Glu Ser Glu Ala Gly Lys Glu Ser Glu Glu Thr Glu Thr
                 995                1000                1005

 Lys Gln Thr Leu Lys Glu Phe Arg Cys Gln Val Ser Asp Cys Ser
                1010                1015                1020

 Arg Ile Phe Gln Ala Ile Thr Gly Leu Ile Gln His Tyr Met Lys
                1025                1030                1035

 Leu His Glu Met Thr Pro Glu Glu Ile Glu Ser Met Thr Ala Ser
                1040                1045                1050

 Val Asp Val Gly Lys Phe Pro Cys Asp Gln Leu Glu Cys Lys Ser
                1055                1060                1065

 Ser Phe Thr Thr Tyr Leu Asn Tyr Val Val His Leu Glu Ala Asp
                1070                1075                1080

 His Gly Ile Gly Leu Arg Ala Ser Lys Thr Glu Glu Asp Gly Val
                1085                1090                1095

 Tyr Lys Cys Asp Cys Glu Gly Cys Asp Arg Ile Tyr Ala Thr Arg
                1100                1105                1110

 Ser Asn Leu Leu Arg His Ile Phe Asn Lys His Asn Asp Lys His
                1115                1120                1125

 Lys Ala His Leu Ile Arg Pro Arg Arg Leu Thr Pro Gly Gln Glu
                1130                1135                1140

 Asn Met Ser Ser Lys Ala Asn Gln Glu Lys Ser Lys Ser Lys His
                1145                1150                1155

 Arg Gly Thr Lys His Ser Arg Cys Gly Lys Glu Gly Ile Lys Met
                1160                1165                1170

 Pro Lys Thr Lys Arg Lys Lys Lys Asn Asn Leu Glu Asn Lys Asn
                1175                1180                1185

 Ala Lys Ile Val Gln Ile Glu Glu Asn Lys Pro Tyr Ser Leu Lys
                1190                1195                1200

 Arg Gly Lys His Val Tyr Ser Ile Lys Ala Arg Asn Asp Ala Leu
                1205                1210                1215

 Ser Glu Cys Thr Ser Arg Phe Val Thr Gln Tyr Pro Cys Met Ile
                1220                1225                1230

 Lys Gly Cys Thr Ser Val Val Thr Ser Glu Ser Asn Ile Ile Arg
                1235                1240                1245

 His Tyr Lys Cys His Lys Leu Ser Lys Ala Phe Thr Ser Gln His
                1250                1255                1260

 Arg Asn Leu Leu Ile Val Phe Lys Arg Cys Cys Asn Ser Gln Val
                1265                1270                1275

 Lys Glu Thr Ser Glu Gln Glu Gly Ala Lys Asn Asp Val Lys Asp
                1280                1285                1290

 Ser Asp Thr Cys Val Ser Glu Ser Asn Asp Asn Ser Arg Thr Thr
                1295                1300                1305

 Ala Thr Val Ser Gln Lys Glu Val Glu Lys Asn Glu Lys Asp Glu
                1310                1315                1320

 Met Asp Glu Leu Thr Glu Leu Phe Ile Thr Lys Leu Ile Asn Glu
                1325                1330                1335

 Asp Ser Thr Ser Val Glu Thr Gln Ala Asn Thr Ser Ser Asn Val
                1340                1345                1350

 Ser Asn Asp Phe Gln Glu Asp Asn Leu Cys Gln Ser Glu Arg Gln
                1355                1360                1365

 Lys Ala Ser Asn Leu Lys Arg Val Asn Lys Glu Lys Asn Val Ser
                1370                1375                1380

 Gln Asn Lys Lys Arg Lys Val Glu Lys Ala Glu Pro Ala Ser Ala
                1385                1390                1395

 Ala Glu Leu Ser Ser Val Arg Lys Glu Glu Glu Thr Ala Val Ala
                1400                1405                1410

 Ile Gln Thr Ile Glu Glu His Pro Ala Ser Phe Asp Trp Ser Ser
                1415                1420                1425

 Phe Lys Pro Met Gly Phe Glu Val Ser Phe Leu Lys Phe Leu Glu
                1430                1435                1440

 Glu Ser Ala Val Lys Gln Lys Lys Asn Thr Asp Lys Asp His Pro
                1445                1450                1455

 Asn Thr Gly Asn Lys Lys Gly Ser His Ser Asn Ser Arg Lys Asn
                1460                1465                1470

 Ile Asp Lys Thr Ala Val Thr Ser Gly Asn His Val Cys Pro Cys
                1475                1480                1485

 Lys Glu Ser Glu Thr Phe Val Gln Phe Ala Asn Pro Ser Gln Leu
                1490                1495                1500

 Gln Cys Ser Asp Asn Val Lys Ile Val Leu Asp Lys Asn Leu Lys
                1505                1510                1515

 Asp Cys Thr Glu Leu Val Leu Lys Gln Leu Gln Glu Met Lys Pro
                1520                1525                1530

 Thr Val Ser Leu Lys Lys Leu Glu Val His Ser Asn Asp Pro Asp
                1535                1540                1545

 Met Ser Val Met Lys Asp Ile Ser Ile Gly Lys Ala Thr Gly Arg
                1550                1555                1560

 Gly Gln Tyr


<210> 2561
<211> 4623
<212> DNA
<213> Homo sapien

<400> 2561
 gtcacgcccc gggcagcttg gctggggcta ggcttccggg gctctgcggt 50

 cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga 100

 tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc 150

 gtgtgggagc ggccgtggtc ggtggaggag atccgcagga gcagccagag 200

 ctggtcgctg gcggccgacg cgggcctact acagtttcta caggaattct 250

 cacagcaaac tatctctagg acccatgaaa tcaagaaaca agtggacgga 300

 ctaatccggg aaaccaaagc cacagattgt cgcctgcata atgtcttcaa 350

 tgacttcctt atgctctcta atacccagtt catagagaat cgtgtatatg 400

 atgaagaagt ggaggagcca gtactcaagg ctgaggcaga aaaaacagag 450

 caggagaaga cacgagagca gaaagaagta gatctcattc ctaaagtcca 500

 ggaggctgtg aactatggct tacaagtatt ggacagtgcc tttgagcaac 550

 ttgatatcaa agcaggaaac tcagactccg aggaagatga tgctaatggg 600

 cgggtggaac tgatccttga accaaaggat ctatacattg atcgtccttt 650

 accatatctc attgggtcaa agctgttcat ggaacaagaa gatgtaggtc 700

 ttggagagct gtccagtgaa gaaggctctg taggcagtga tcgtggcagt 750

 attgtggaca ctgaggaaga gaaagaagag gaggagtcag atgaagattt 800

 tgcccatcac agtgacaatg aacaaaacca gcacaccaca caaatgagtg 850

 atgaggaaga ggatgatgat ggctgtgacc tttttgctga ctctgagaag 900

 gaggaggaag atattgagga cattgaagaa aatactagac ctaaaagaag 950

 cagacctaca tcgtttgcag atgagctggc tgcccgcatc aagggggatg 1000

 ccatgggtcg agtggacgag gagccgacaa ccttaccctc aggagaagca 1050

 aaacctcgga agacactcaa agagaagaag gaaaggagaa ctccttcaga 1100

 cgatgaagag gataacttat tcgcaccccc caagctgacc gacgaggact 1150

 tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta 1200

 tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga 1250

 tcggcaagct ggagcctctg ttaaggagga gtcttcatca tccaaacctg 1300

 gaaagaaaat cccagcagga gctgtttctg tatttttagg agacacggat 1350

 gtgtttggtg ctgcctccgt tccatcactg aaggagccac agaagcctga 1400

 gcagcccact ccaaggaaaa gcccctatgg tccccctccc actggcctct 1450

 ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac 1500

 agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg 1550

 tgacgaagaa ggagatctgt tcaaagaaaa agccgtagca tcgccagaag 1600

 ccactgtgag tcagacagat gaaaataaag caagagcaga aaaaaaggtt 1650

 accttatctt ccagcaagaa tctcaagccc tcatcagaaa caaagactca 1700

 aaaaggctta ttttcagatg aggaggactc tgaggatttg ttttcttctc 1750

 aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc 1800

 acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg 1850

 gggtacagct gctaagaagc agacattgtc tctacaagct cagagagaag 1900

 agaaagcaaa agcctccgag ctctccaaaa agaaagcatc tgccctgttg 1950

 ttcagcagtg atgaggagga ccagtggaat attcctgctt cacagaccca 2000

 cttagcatct gacagcaggt ctaaaggaga acccagggat tctgggaccc 2050

 tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa 2100

 gacaaagaag atgatctttt tgccattgcc aaggacagcc aaaagaagac 2150

 ccagagagtg tcactcctct ttgaagacga tgttgatagc ggaggctctc 2200

 tgtttggctc tcctcccaca tctgttcctc ctgcaacaaa gaaaaaagag 2250

 actgtctctg aggcaccacc tttgctgttc agcgatgaag aagagaagga 2300

 ggcacaactt ggagtgaagt ctgtggataa gaaggttgag agtgccaagg 2350

 agtcattaaa atttgggaga actgatgtgg ctgagtcaga aaaggaagga 2400

 cttttgacta gatctgctca ggaaacagtc aagcattctg atttattttc 2450

 ttcatcatcc ccatgggaca aaggaaccaa gcctagaacc aaaactgttc 2500

 ttagcttgtt tgatgaggaa gaggataaaa tggaagatca aaacattatc 2550

 caggctccac agaaagaagt aggaaagggc tgcgatcctg atgcccaccc 2600

 caagagcaca ggtgtcttcc aggatgaaga gctgcttttc agccacaagc 2650

 tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa 2700

 accaagctgt tagagccaag tgttgggagc ctgtttgggg atgatgaaga 2750

 tgatgatctt ttcagctctg ccaagtccca gcctttggta caagagaaaa 2800

 agagagtagt gaaaaaagac cactctgtta actctttcaa aaaccagaaa 2850

 catcctgaat ccattcaagg tagtaaagaa aaaggcatat ggaagccgga 2900

 aacacctcag gcaaatttag cgatcaaccc agcggccttg ctgcccacag 2950

 cggcttccca gatctctgaa gtaaagcctg ttttgccaga attggctttt 3000

 ccttcatctg aacacagaag gagccacggt ctggaaagtg tgcctgtcct 3050

 tcccgggagt ggggaggccg gtgtgagttt tgatcttcca gctcaggcag 3100

 acaccttaca cagtgcaaac aagagccgtg tcaagatgag agggaagcgt 3150

 agaccgcaga cccgtgcagc taggcggctg gctgctcagg agtccagcga 3200

 ggctgaggac atgagcatcc ccagaggacc cattgcacag tgggctgatg 3250

 gcgccatttc cccaaatggc catcggccac agctcagagc agccagtgga 3300

 gaagacagca ctgaggaggc cctggcagct gccgctgcac cttgggaagg 3350

 tggtcctgtg cctggagtgg acacaagccc ctttgcaaag tctctgggtc 3400

 attccagagg ggaggctgac ctttttgatt ctggggacat tttttccacg 3450

 ggcactggat ctcagtccgt ggagagaaca aaacccaagg caaagatagc 3500

 agagaatcct gccaacccac cagtgggtgg taaagcaaag agccccatgt 3550

 ttcctgctct aggcgaggcc agcagtgatg atgatctctt tcagtctgct 3600

 aaaccaaaac cagcaaagaa aacaaatccc tttcctctcc tggaagatga 3650

 ggatgacctc tttacagatc agaaagtcaa gaagaatgag acaaaatcca 3700

 gtagtcagca ggatgtcata ttaacaacac aagatatttt tgaggatgat 3750

 atatttgcta cggaagcaat taaaccctct cagaaaacca gagagaagga 3800

 gaaaacattg gaatctaatt tatttgatga taacattgat atctttgctg 3850

 acttaactgt aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag 3900

 tctatatttg atgatgatat ggatgacatc ttctcctctg gtatccaggc 3950

 taagacaacc aaaccaaaaa gccgatctgc acaggccgca cctgaaccaa 4000

 gatttgaaca caaggtgtcc aacatctttg atgatcccct gaatgccttt 4050

 ggaggccagt agagcacaca gggtatccac atgttaccct gcagctacat 4100

 tgttgagtta gtgatgatgt tgtatatgct gatggtctta actggattac 4150

 aaaaagcaaa tactagaaca gctagctcat cgttcaccca atgtacttgg 4200

 tatttttctg cactggttta atcatgctta atactacaaa acaaaaataa 4250

 atatttcaca gtggttggtt tgttttgttt ttaaaccaca gtttgattta 4300

 gttagccttg ctggggccat aatatgcttc agggtgtgta aaagaagaaa 4350

 tctctttgtg gctttcatgg gcagggaatc tcagagatag caaatgccac 4400

 ctgaccagaa gtctttgtta tatggatggg aaccctaact tagggcttgg 4450

 gcaggggaaa gagaaagaag atgagagatt atacttcatg agtcttagca 4500

 atatgggagc aggttttcac tgaattctga gggtgcctct gcatgtcctc 4550

 caaggcaaag tttggcaaac tgtggccccc ccactgtcat attttgttaa 4600

 taaaatttta ttggaacaca atc 4623

<210> 2562
<211> 1353
<212> PRT
<213> Homo sapien

<400> 2562
 Val Thr Pro Arg Ala Ala Trp Leu Gly Leu Gly Phe Arg Gly Ser
   1               5                  10                  15

 Ala Val Leu Gly Leu Cys Trp Gln Pro Arg Ser Pro Pro Ser Arg
                  20                  25                  30

 Ala Ala Gly Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val
                  35                  40                  45

 Pro Ala Ser Glu Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu
                  50                  55                  60

 Ile Arg Arg Ser Ser Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly
                  65                  70                  75

 Leu Leu Gln Phe Leu Gln Glu Phe Ser Gln Gln Thr Ile Ser Arg
                  80                  85                  90

 Thr His Glu Ile Lys Lys Gln Val Asp Gly Leu Ile Arg Glu Thr
                  95                 100                 105

 Lys Ala Thr Asp Cys Arg Leu His Asn Val Phe Asn Asp Phe Leu
                 110                 115                 120

 Met Leu Ser Asn Thr Gln Phe Ile Glu Asn Arg Val Tyr Asp Glu
                 125                 130                 135

 Glu Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu
                 140                 145                 150

 Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys
                 155                 160                 165

 Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala
                 170                 175                 180

 Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu
                 185                 190                 195

 Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys Asp
                 200                 205                 210

 Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu
                 215                 220                 225

 Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu
                 230                 235                 240

 Glu Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu
                 245                 250                 255

 Glu Glu Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His
                 260                 265                 270

 Ser Asp Asn Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu
                 275                 280                 285

 Glu Glu Asp Asp Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys
                 290                 295                 300

 Glu Glu Glu Asp Ile Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys
                 305                 310                 315

 Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala Arg Ile
                 320                 325                 330

 Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr Leu
                 335                 340                 345

 Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys
                 350                 355                 360

 Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala
                 365                 370                 375

 Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly
                 380                 385                 390

 Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp
                 395                 400                 405

 Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala
                 410                 415                 420

 Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys
                 425                 430                 435

 Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp
                 440                 445                 450

 Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys
                 455                 460                 465

 Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro
                 470                 475                 480

 Thr Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe
                 485                 490                 495

 Phe Ser Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln
                 500                 505                 510

 Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys
                 515                 520                 525

 Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp
                 530                 535                 540

 Glu Asn Lys Ala Arg Ala Glu Lys Lys Val Thr Leu Ser Ser Ser
                 545                 550                 555

 Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln Lys Gly Leu
                 560                 565                 570

 Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser Gln Ser
                 575                 580                 585

 Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro
                 590                 595                 600

 Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu
                 605                 610                 615

 Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala
                 620                 625                 630

 Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys
                 635                 640                 645

 Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn
                 650                 655                 660

 Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys
                 665                 670                 675

 Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys
                 680                 685                 690

 Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp
                 695                 700                 705

 Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val
                 710                 715                 720

 Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe
                 725                 730                 735

 Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu
                 740                 745                 750

 Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu
                 755                 760                 765

 Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu
                 770                 775                 780

 Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu
                 785                 790                 795

 Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val
                 800                 805                 810

 Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly
                 815                 820                 825

 Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu
                 830                 835                 840

 Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys
                 845                 850                 855

 Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr
                 860                 865                 870

 Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln
                 875                 880                 885

 Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys
                 890                 895                 900

 Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp
                 905                 910                 915

 Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val
                 920                 925                 930

 Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser
                 935                 940                 945

 Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu
                 950                 955                 960

 Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile
                 965                 970                 975

 Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu
                 980                 985                 990

 Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His
                 995                1000                1005

 Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser
                1010                1015                1020

 Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr
                1025                1030                1035

 Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg
                1040                1045                1050

 Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser
                1055                1060                1065

 Ser Glu Ala Glu Asp Met Ser Ile Pro Arg Gly Pro Ile Ala Gln
                1070                1075                1080

 Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu
                1085                1090                1095

 Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala
                1100                1105                1110

 Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr
                1115                1120                1125

 Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp
                1130                1135                1140

 Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln
                1145                1150                1155

 Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro
                1160                1165                1170

 Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro
                1175                1180                1185

 Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala
                1190                1195                1200

 Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu
                1205                1210                1215

 Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu
                1220                1225                1230

 Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp
                1235                1240                1245

 Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser
                1250                1255                1260

 Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe
                1265                1270                1275

 Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys
                1280                1285                1290

 Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp
                1295                1300                1305

 Asp Met Asp Asp Ile Phe Ser Ser Gly Ile Gln Ala Lys Thr Thr
                1310                1315                1320

 Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe
                1325                1330                1335

 Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe
                1340                1345                1350

 Gly Gly Gln


<210> 2563
<211> 7596
<212> DNA
<213> Homo sapien

<400> 2563
 gtggtcgcgg ctggggacgt gcgcccgcgc caccatcttc ggctgaagag 50

 gcaattgctt ttggatcgtt ccatttacaa tggcgcagag aactggactc 100

 gaggatccag agaggtatct ctttgtggac agggctgtca tctacaaccc 150

 tgccactcaa gctgattgga cagctaaaaa gctagtgtgg attccatcag 200

 aacgccatgg ttttgaggca gctagtatca aagaagaacg gggagatgaa 250

 gttatggtgg agttggcaga gaatggaaag aaagcaatgg tcaacaaaga 300

 tgatattcag aagatgaacc cacctaagtt ttccaaggtg gaggatatgg 350

 cagaattgac atgcttgaat gaagcttccg ttttacataa tctgaaggat 400

 cgctactatt caggactaat ctatacttat tctggactct tctgtgtagt 450

 tataaaccct tacaagaatc ttccaattta ctctgagaat attattgaaa 500

 tgtacagagg gaagaagcgt catgagatgc ctccacacat ctatgctata 550

 tctgaatctg cttacagatg catgcttcaa gatcgtgagg accagtcaat 600

 tctttgcacg ggtgagtcag gtgctgggaa gacagaaaat acaaagaaag 650

 ttattcagta ccttgcccat gttgcttctt cacataaagg aagaaaggac 700

 cataatattc ctggggaact tgaacggcag cttttgcaag caaatccaat 750

 tctcgaatca tttggaaatg cgaagactgt gaaaaatgat aactcatctc 800

 gttttggcaa atttattcgg atcaactttg atgtaactgg ctatatcgtt 850

 ggggccaaca ttgaaacata ccttctggaa aagtctcgtg ctgttcgtca 900

 agcaaaagat gaacgtactt ttcatatctt ttaccagttg ttatctggag 950

 caggagaaca cctaaagtct gatttgcttc ttgaaggatt taataactac 1000

 aggtttctct ccaatggcta tattcctatt ccgggacagc aagacaaaga 1050

 taatttccag gagaccatgg aagcaatgca cataatgggc ttctcccatg 1100

 aagagattct gtcaatgctt aaagtagtat cttcagtgct acagtttgga 1150

 aatatttctt tcaaaaagga gagaaatact gatcaagctt ccatgccaga 1200

 aaatacagtt gcgcagaagc tctgccatct tcttgggatg aatgtgatgg 1250

 agtttactcg ggccatcctg actccccgga tcaaggtcgg ccgagactat 1300

 gtgcaaaaag cccagaccaa agaacaggca gattttgcag tagaagcatt 1350

 ggcaaaagct acctatgagc ggctctttcg ctggctcgtt catcgcatca 1400

 ataaagctct ggataggacc aaacgtcagg gagcatcttt cattggaatc 1450

 ctggatattg ctggatttga aatttttgag ctgaactcct ttgaacaact 1500

 ttgcatcaac tacaccaatg agaagctgca gcagctgttc aaccacacca 1550

 tgtttatcct agaacaagag gaataccagc gcgaaggcat cgagtggaac 1600

 ttcatcgatt tcgggctgga tctgcagcca tgcatcgacc taatagagag 1650

 acctgcgaac cctcctggtg tactggccct tttggatgaa gaatgctggt 1700

 tccctaaagc cacagataaa acctttgttg aaaaactggt tcaagagcaa 1750

 ggttcccact ccaagtttca gaaacctcga caattaaaag acaaagctga 1800

 tttttgcatt atacattatg cagggaaggt ggactataag gcagatgagt 1850

 ggctgatgaa gaatatggac cccctgaatg acaacgtggc cacccttttg 1900

 caccagtcat cagacagatt tgtggcagag ctttggaaag atgtggaccg 1950

 tatcgtgggt ctggatcaag tcactggtat gactgagaca gcttttggct 2000

 ccgcatataa aaccaagaag ggcatgtttc gtaccgttgg gcaactctac 2050

 aaagaatctc tcaccaagct gatggcaact ctccgaaaca ccaaccctaa 2100

 ctttgttcgt tgtatcattc caaatcacga gaagagggct ggaaaattgg 2150

 atccacacct agtcctagat cagcttcgct gtaatggtgt cctggaaggg 2200

 atccgaatct gtcgccaggg cttccctaac cgaatagttt tccaggaatt 2250

 cagacagaga tatgagatcc taactccaaa tgctattcct aaaggtttta 2300

 tggatggtaa acaggcctgt gaacgaatga tccgggcttt agaattggac 2350

 ccaaacttgt acagaattgg acagagcaag atatttttca gagctggagt 2400

 tctggcacac ttagaggaag aaagagattt aaaaatcacc gatatcatta 2450

 tcttcttcca ggccgtttgc agaggttgcc tggccagaaa ggcctttgcc 2500

 aagaagcagc agcaactaag tgccttaaag gtcttgcagc ggaactgtgc 2550

 cgcgtacctg aaattacggc actggcagtg gtggcgagtc ttcacaaagg 2600

 tgaagccgct tctacaagtg actcgccagg aggaagaact tcaggccaaa 2650

 gatgaagagc tgttgaaggt gaaggagaag cagacaaagg tggaaggaga 2700

 gctggaggag atggagcgga agcaccagca gcttttagaa gagaagaata 2750

 tccttgcaga acaactacaa gcagagactg agctctttgc tgaagcagaa 2800

 gagatgaggg caagacttgc tgctaaaaag caggaattag aagagattct 2850

 acatgacttg gagtctaggg ttgaagaaga agaagaaaga aaccaaatcc 2900

 tccaaaatga aaagaaaaaa atgcaagcac atattcagga cctggaagaa 2950

 cagctagacg aggaggaagg ggctcggcaa aagctgcagc tggaaaaggt 3000

 gacagcagag gccaagatca agaagatgga agaggagatt ctgcttctcg 3050

 aggaccaaaa ttccaagttc atcaaagaaa agaaactcat ggaagatcgc 3100

 attgctgagt gttcctctca gctggctgaa gaggaagaaa aggcgaaaaa 3150

 cttggccaaa atcaggaata agcaagaagt gatgatctca gatttagaag 3200

 aacgcttaaa gaaggaagaa aagactcgtc aggaactgga aaaggccaaa 3250

 agaaaactcg acggggagac gaccgacctg caggaccaga tcgcagagct 3300

 gcaggcgcag attgatgagc tcaagctgca gctggccaag aaggaggagg 3350

 agctgcaggg cgcactggcc agaggtgatg atgaaacact ccataagaac 3400

 aatgccctta aagttgtgcg agagctacaa gcccaaattg ctgaacttca 3450

 ggaagacttt gaatccgaga aggcttcacg gaacaaggcc gaaaagcaga 3500

 aaagggactt gagtgaggaa ctggaagctc tgaaaacaga gctggaggac 3550

 acgctggaca ccacggcagc ccagcaggaa ctacgtacaa aacgtgaaca 3600

 agaagtggca gagctgaaga aagctcttga ggaggaaact aagaaccatg 3650

 aagctcaaat ccaggacatg agacaaagac acgcaacagc cctggaggag 3700

 ctctcagagc agctggaaca ggccaagcgg ttcaaagcaa atctagagaa 3750

 gaacaagcag ggcctggaga cagataacaa ggagctggcg tgtgaggtga 3800

 aggtcctgca gcaggtcaag gctgagtctg agcacaagag gaagaagctc 3850

 gacgcgcagg tccaggagct ccatgccaag gtctctgaag gcgacaggct 3900

 cagggtggag ctggcggaga aagcaagtaa gctgcagaat gagctagata 3950

 atgtctccac ccttctggaa gaagcagaga agaagggtat taaatttgct 4000

 aaggatgcag ctagtcttga gtctcaacta caggatacac aggagcttct 4050

 tcaggaggag acacgccaga aactaaacct gagcagtcgg atccggcagc 4100

 tggaagagga gaagaacagt cttcaggagc agcaggagga ggaggaggag 4150

 gccaggaaga acctggagaa gcaagtgctg gccctgcagt cccagttggc 4200

 tgataccaag aagaaagtag atgacgacct gggaacaatt gaaagtctgg 4250

 aagaagccaa gaagaagctt ctgaaggacg cggaggccct gagccagcgc 4300

 ctggaggaga aggcactggc gtatgacaaa ctggagaaga ccaagaaccg 4350

 cctgcagcag gagctggacg acctcacggt ggacctggac caccagcgcc 4400

 aggtcgcctc caacttggag aagaagcaga agaagtttga ccagctgtta 4450

 gcagaagaga agagcatctc tgctcgctat gccgaagagc gggaccgggc 4500

 cgaagccgag gccagagaga aagaaaccaa agccctgtca ctggcccggg 4550

 ccctcgagga agccctggag gccaaggagg agtttgagag gcagaacaag 4600

 cagctccgag cagacatgga agacctcatg agctccaaag atgatgtggg 4650

 aaaaaacgtt cacgaacttg aaaaatccaa acgggcccta gagcagcagg 4700

 tggaggaaat gaggacccag ctggaggagc tggaagacga actccaggcc 4750

 acggaagatg ccaagcttcg tctggaggtc aacatgcagg ccatgaaggc 4800

 gcagttcgag agagacctgc aaaccaggga tgagcagaat gaagagaaga 4850

 agcggctgct gatcaaacag gtgcgggagc tcgaggcgga gctggaggat 4900

 gagaggaaac agcgggcgct tgctgtagct tcgaagaaaa agatggagat 4950

 agacctgaag gacctcgaag cccaaatcga ggctgcgaac aaagctcggg 5000

 atgaggtgat taagcagctc cgcaagctcc aggctcagat gaaggattac 5050

 caacgtgaat tagaagaagc tcgtgcatcc agagatgaga tttttgctca 5100

 atccaaagag agtgaaaaga aattgaagag tctggaagca gaaatccttc 5150

 aattgcagga ggaacttgcc tcatctgagc gagcccgccg acacgccgag 5200

 caggagagag atgagctggc ggacgagatc accaacagcg cctctggcaa 5250

 gtccgcgctg ctggatgaga agcggcgtct ggaagctcgg atcgcacagc 5300

 tggaggagga gctggaagag gagcagagca acatggagct gctcaacgac 5350

 cgcttccgca agaccactct acaggtggac acactgaacg ccgagctagc 5400

 agccgagcgc agcgccgccc agaagagtga caatgcacgc cagcaactgg 5450

 agcggcagaa caaggagctg aaggccaagc tgcaggaact cgagggtgct 5500

 gtcaagtcta agttcaaggc caccatctca gccctggagg ccaagattgg 5550

 gcagctggag gagcagcttg agcaggaagc caaggaacga gcagccgcca 5600

 acaaattagt ccgtcgcact gagaagaagc tgaaagaaat cttcatgcag 5650

 gttgaggatg agcgtcgaca cgcggaccag tataaagagc agatggagaa 5700

 ggccaacgct cggatgaagc agcttaaacg ccagctggag gaagcagaag 5750

 aagaagcgac gcgtgccaac gcatctcggc gtaaactcca gcgggaactg 5800

 gatgatgcca ccgaggccaa cgagggcctg agccgcgagg tcagcaccct 5850

 gaagaaccgg ctgaggcggg gtggccccat cagcttctct tccagccgat 5900

 ctggccggcg ccagctgcac cttgaaggag cttccctgga gctctccgac 5950

 gatgacacag aaagtaagac cagtgatgtc aacgagacgc agccacccca 6000

 gtcagagtaa agttgcagga agccagagga ggcaatacag tgggacagtt 6050

 aggaatgcac ccggggcctc ctgcagattt cggaaattgg caagctacgg 6100

 gattccttcc tgaaagatca actgtgtctt aaggctctcc agcctatgca 6150

 tactgtatcc tgcttcagac ttaggtacaa ttgctcccct ttttatatac 6200

 agacacacac aggacacata tattaaacag attgtttcat cattgcatct 6250

 attttccata tagtcatcaa gagaccattt tataaaacat ggtaagaccc 6300

 tttttaaaac aaactccagg cccttggttg cgggtcgctg ggttattggg 6350

 gcagcgccgt ggtcgtcact cagtcgctct gcatgctctc tgtcatacag 6400

 acaggtaacc tagttctgtg ttcacgtggc ccccgactcc tcagccacat 6450

 caagtctcct agaccactgt ggactctaaa ctgcacttgt ctctctcatt 6500

 tccttcaaat aatgatcaat gctatttcag tgagcaaact gtgaaagggg 6550

 ctttggaaag agtaggaggg gtgggctgga tcggaagcaa cacccatttg 6600

 gggttaccat gtccatcccc caaggggggc cctccccctc gagtcgatgg 6650

 tgtcccgcat ctactcatgt gaactggcct tggcgagggc tggtctgtgc 6700

 atagaaggga tagtggccac actgcagctg aggccccagg tggcagccat 6750

 ggatcatgta gacttccaga tggtctcccg aaccgcctgg ctctgccggc 6800

 gccctcctca cgtcaggagc aagcagccgt ggacccctaa gccgagctgg 6850

 tggaaggccc ctccccgtcg ccagccgggc cctcatgctg accttgcaaa 6900

 ttcagccgct gctttgagcc caaaatggga atattggttt tgtgtccgag 6950

 gcttgttcca agtttgtcaa tgaggtttat ggagcctcca gaacagatgc 7000

 catcttcctg aatgttgaca tgccagtggg tgtgactcct tcatttttcc 7050

 ttctcccttc cctttggaca gtgttacagt gaacacttag catcctgttt 7100

 ttggttggta gttaagcaaa ctgacattac ggaaagtgcc ttagacacta 7150

 cagtactaag acaatgttga atatatcatt cgcctctata acaatttaat 7200

 gtattcagtt ttgactgtgc ttcatatcat gtacctctct agtcaaagtg 7250

 gtattacaga cattcagtga caatgaatca gtgttaattc taaatccttg 7300

 atcctctgca atgtgcttga aaacacaaac cttttgggtt aaaagcttta 7350

 acatctatta ggaagaattt gtcctgtggg tttggaatct tggattttcc 7400

 ccctttatga actgtactgg ctgttgacca ccagacacct gaccgcaaat 7450

 atcttttctt gtattcccat atttctagac aatgattttt gtaagacaat 7500

 aaatttattc attatagata tttgcgcctg ctctgtttac ttgaagaaaa 7550

 aagcacccgt ggagaataaa gagacctcaa taaacaaaaa aaaaaa 7596

<210> 2564
<211> 1976
<212> PRT
<213> Homo sapien

<400> 2564
 Met Ala Gln Arg Thr Gly Leu Glu Asp Pro Glu Arg Tyr Leu Phe
   1               5                  10                  15

 Val Asp Arg Ala Val Ile Tyr Asn Pro Ala Thr Gln Ala Asp Trp
                  20                  25                  30

 Thr Ala Lys Lys Leu Val Trp Ile Pro Ser Glu Arg His Gly Phe
                  35                  40                  45

 Glu Ala Ala Ser Ile Lys Glu Glu Arg Gly Asp Glu Val Met Val
                  50                  55                  60

 Glu Leu Ala Glu Asn Gly Lys Lys Ala Met Val Asn Lys Asp Asp
                  65                  70                  75

 Ile Gln Lys Met Asn Pro Pro Lys Phe Ser Lys Val Glu Asp Met
                  80                  85                  90

 Ala Glu Leu Thr Cys Leu Asn Glu Ala Ser Val Leu His Asn Leu
                  95                 100                 105

 Lys Asp Arg Tyr Tyr Ser Gly Leu Ile Tyr Thr Tyr Ser Gly Leu
                 110                 115                 120

 Phe Cys Val Val Ile Asn Pro Tyr Lys Asn Leu Pro Ile Tyr Ser
                 125                 130                 135

 Glu Asn Ile Ile Glu Met Tyr Arg Gly Lys Lys Arg His Glu Met
                 140                 145                 150

 Pro Pro His Ile Tyr Ala Ile Ser Glu Ser Ala Tyr Arg Cys Met
                 155                 160                 165

 Leu Gln Asp Arg Glu Asp Gln Ser Ile Leu Cys Thr Gly Glu Ser
                 170                 175                 180

 Gly Ala Gly Lys Thr Glu Asn Thr Lys Lys Val Ile Gln Tyr Leu
                 185                 190                 195

 Ala His Val Ala Ser Ser His Lys Gly Arg Lys Asp His Asn Ile
                 200                 205                 210

 Pro Gly Glu Leu Glu Arg Gln Leu Leu Gln Ala Asn Pro Ile Leu
                 215                 220                 225

 Glu Ser Phe Gly Asn Ala Lys Thr Val Lys Asn Asp Asn Ser Ser
                 230                 235                 240

 Arg Phe Gly Lys Phe Ile Arg Ile Asn Phe Asp Val Thr Gly Tyr
                 245                 250                 255

 Ile Val Gly Ala Asn Ile Glu Thr Tyr Leu Leu Glu Lys Ser Arg
                 260                 265                 270

 Ala Val Arg Gln Ala Lys Asp Glu Arg Thr Phe His Ile Phe Tyr
                 275                 280                 285

 Gln Leu Leu Ser Gly Ala Gly Glu His Leu Lys Ser Asp Leu Leu
                 290                 295                 300

 Leu Glu Gly Phe Asn Asn Tyr Arg Phe Leu Ser Asn Gly Tyr Ile
                 305                 310                 315

 Pro Ile Pro Gly Gln Gln Asp Lys Asp Asn Phe Gln Glu Thr Met
                 320                 325                 330

 Glu Ala Met His Ile Met Gly Phe Ser His Glu Glu Ile Leu Ser
                 335                 340                 345

 Met Leu Lys Val Val Ser Ser Val Leu Gln Phe Gly Asn Ile Ser
                 350                 355                 360

 Phe Lys Lys Glu Arg Asn Thr Asp Gln Ala Ser Met Pro Glu Asn
                 365                 370                 375

 Thr Val Ala Gln Lys Leu Cys His Leu Leu Gly Met Asn Val Met
                 380                 385                 390

 Glu Phe Thr Arg Ala Ile Leu Thr Pro Arg Ile Lys Val Gly Arg
                 395                 400                 405

 Asp Tyr Val Gln Lys Ala Gln Thr Lys Glu Gln Ala Asp Phe Ala
                 410                 415                 420

 Val Glu Ala Leu Ala Lys Ala Thr Tyr Glu Arg Leu Phe Arg Trp
                 425                 430                 435

 Leu Val His Arg Ile Asn Lys Ala Leu Asp Arg Thr Lys Arg Gln
                 440                 445                 450

 Gly Ala Ser Phe Ile Gly Ile Leu Asp Ile Ala Gly Phe Glu Ile
                 455                 460                 465

 Phe Glu Leu Asn Ser Phe Glu Gln Leu Cys Ile Asn Tyr Thr Asn
                 470                 475                 480

 Glu Lys Leu Gln Gln Leu Phe Asn His Thr Met Phe Ile Leu Glu
                 485                 490                 495

 Gln Glu Glu Tyr Gln Arg Glu Gly Ile Glu Trp Asn Phe Ile Asp
                 500                 505                 510

 Phe Gly Leu Asp Leu Gln Pro Cys Ile Asp Leu Ile Glu Arg Pro
                 515                 520                 525

 Ala Asn Pro Pro Gly Val Leu Ala Leu Leu Asp Glu Glu Cys Trp
                 530                 535                 540

 Phe Pro Lys Ala Thr Asp Lys Thr Phe Val Glu Lys Leu Val Gln
                 545                 550                 555

 Glu Gln Gly Ser His Ser Lys Phe Gln Lys Pro Arg Gln Leu Lys
                 560                 565                 570

 Asp Lys Ala Asp Phe Cys Ile Ile His Tyr Ala Gly Lys Val Asp
                 575                 580                 585

 Tyr Lys Ala Asp Glu Trp Leu Met Lys Asn Met Asp Pro Leu Asn
                 590                 595                 600

 Asp Asn Val Ala Thr Leu Leu His Gln Ser Ser Asp Arg Phe Val
                 605                 610                 615

 Ala Glu Leu Trp Lys Asp Val Asp Arg Ile Val Gly Leu Asp Gln
                 620                 625                 630

 Val Thr Gly Met Thr Glu Thr Ala Phe Gly Ser Ala Tyr Lys Thr
                 635                 640                 645

 Lys Lys Gly Met Phe Arg Thr Val Gly Gln Leu Tyr Lys Glu Ser
                 650                 655                 660

 Leu Thr Lys Leu Met Ala Thr Leu Arg Asn Thr Asn Pro Asn Phe
                 665                 670                 675

 Val Arg Cys Ile Ile Pro Asn His Glu Lys Arg Ala Gly Lys Leu
                 680                 685                 690

 Asp Pro His Leu Val Leu Asp Gln Leu Arg Cys Asn Gly Val Leu
                 695                 700                 705

 Glu Gly Ile Arg Ile Cys Arg Gln Gly Phe Pro Asn Arg Ile Val
                 710                 715                 720

 Phe Gln Glu Phe Arg Gln Arg Tyr Glu Ile Leu Thr Pro Asn Ala
                 725                 730                 735

 Ile Pro Lys Gly Phe Met Asp Gly Lys Gln Ala Cys Glu Arg Met
                 740                 745                 750

 Ile Arg Ala Leu Glu Leu Asp Pro Asn Leu Tyr Arg Ile Gly Gln
                 755                 760                 765

 Ser Lys Ile Phe Phe Arg Ala Gly Val Leu Ala His Leu Glu Glu
                 770                 775                 780

 Glu Arg Asp Leu Lys Ile Thr Asp Ile Ile Ile Phe Phe Gln Ala
                 785                 790                 795

 Val Cys Arg Gly Cys Leu Ala Arg Lys Ala Phe Ala Lys Lys Gln
                 800                 805                 810

 Gln Gln Leu Ser Ala Leu Lys Val Leu Gln Arg Asn Cys Ala Ala
                 815                 820                 825

 Tyr Leu Lys Leu Arg His Trp Gln Trp Trp Arg Val Phe Thr Lys
                 830                 835                 840

 Val Lys Pro Leu Leu Gln Val Thr Arg Gln Glu Glu Glu Leu Gln
                 845                 850                 855

 Ala Lys Asp Glu Glu Leu Leu Lys Val Lys Glu Lys Gln Thr Lys
                 860                 865                 870

 Val Glu Gly Glu Leu Glu Glu Met Glu Arg Lys His Gln Gln Leu
                 875                 880                 885

 Leu Glu Glu Lys Asn Ile Leu Ala Glu Gln Leu Gln Ala Glu Thr
                 890                 895                 900

 Glu Leu Phe Ala Glu Ala Glu Glu Met Arg Ala Arg Leu Ala Ala
                 905                 910                 915

 Lys Lys Gln Glu Leu Glu Glu Ile Leu His Asp Leu Glu Ser Arg
                 920                 925                 930

 Val Glu Glu Glu Glu Glu Arg Asn Gln Ile Leu Gln Asn Glu Lys
                 935                 940                 945

 Lys Lys Met Gln Ala His Ile Gln Asp Leu Glu Glu Gln Leu Asp
                 950                 955                 960

 Glu Glu Glu Gly Ala Arg Gln Lys Leu Gln Leu Glu Lys Val Thr
                 965                 970                 975

 Ala Glu Ala Lys Ile Lys Lys Met Glu Glu Glu Ile Leu Leu Leu
                 980                 985                 990

 Glu Asp Gln Asn Ser Lys Phe Ile Lys Glu Lys Lys Leu Met Glu
                 995                1000                1005

 Asp Arg Ile Ala Glu Cys Ser Ser Gln Leu Ala Glu Glu Glu Glu
                1010                1015                1020

 Lys Ala Lys Asn Leu Ala Lys Ile Arg Asn Lys Gln Glu Val Met
                1025                1030                1035

 Ile Ser Asp Leu Glu Glu Arg Leu Lys Lys Glu Glu Lys Thr Arg
                1040                1045                1050

 Gln Glu Leu Glu Lys Ala Lys Arg Lys Leu Asp Gly Glu Thr Thr
                1055                1060                1065

 Asp Leu Gln Asp Gln Ile Ala Glu Leu Gln Ala Gln Ile Asp Glu
                1070                1075                1080

 Leu Lys Leu Gln Leu Ala Lys Lys Glu Glu Glu Leu Gln Gly Ala
                1085                1090                1095

 Leu Ala Arg Gly Asp Asp Glu Thr Leu His Lys Asn Asn Ala Leu
                1100                1105                1110

 Lys Val Val Arg Glu Leu Gln Ala Gln Ile Ala Glu Leu Gln Glu
                1115                1120                1125

 Asp Phe Glu Ser Glu Lys Ala Ser Arg Asn Lys Ala Glu Lys Gln
                1130                1135                1140

 Lys Arg Asp Leu Ser Glu Glu Leu Glu Ala Leu Lys Thr Glu Leu
                1145                1150                1155

 Glu Asp Thr Leu Asp Thr Thr Ala Ala Gln Gln Glu Leu Arg Thr
                1160                1165                1170

 Lys Arg Glu Gln Glu Val Ala Glu Leu Lys Lys Ala Leu Glu Glu
                1175                1180                1185

 Glu Thr Lys Asn His Glu Ala Gln Ile Gln Asp Met Arg Gln Arg
                1190                1195                1200

 His Ala Thr Ala Leu Glu Glu Leu Ser Glu Gln Leu Glu Gln Ala
                1205                1210                1215

 Lys Arg Phe Lys Ala Asn Leu Glu Lys Asn Lys Gln Gly Leu Glu
                1220                1225                1230

 Thr Asp Asn Lys Glu Leu Ala Cys Glu Val Lys Val Leu Gln Gln
                1235                1240                1245

 Val Lys Ala Glu Ser Glu His Lys Arg Lys Lys Leu Asp Ala Gln
                1250                1255                1260

 Val Gln Glu Leu His Ala Lys Val Ser Glu Gly Asp Arg Leu Arg
                1265                1270                1275

 Val Glu Leu Ala Glu Lys Ala Ser Lys Leu Gln Asn Glu Leu Asp
                1280                1285                1290

 Asn Val Ser Thr Leu Leu Glu Glu Ala Glu Lys Lys Gly Ile Lys
                1295                1300                1305

 Phe Ala Lys Asp Ala Ala Ser Leu Glu Ser Gln Leu Gln Asp Thr
                1310                1315                1320

 Gln Glu Leu Leu Gln Glu Glu Thr Arg Gln Lys Leu Asn Leu Ser
                1325                1330                1335

 Ser Arg Ile Arg Gln Leu Glu Glu Glu Lys Asn Ser Leu Gln Glu
                1340                1345                1350

 Gln Gln Glu Glu Glu Glu Glu Ala Arg Lys Asn Leu Glu Lys Gln
                1355                1360                1365

 Val Leu Ala Leu Gln Ser Gln Leu Ala Asp Thr Lys Lys Lys Val
                1370                1375                1380

 Asp Asp Asp Leu Gly Thr Ile Glu Ser Leu Glu Glu Ala Lys Lys
                1385                1390                1395

 Lys Leu Leu Lys Asp Ala Glu Ala Leu Ser Gln Arg Leu Glu Glu
                1400                1405                1410

 Lys Ala Leu Ala Tyr Asp Lys Leu Glu Lys Thr Lys Asn Arg Leu
                1415                1420                1425

 Gln Gln Glu Leu Asp Asp Leu Thr Val Asp Leu Asp His Gln Arg
                1430                1435                1440

 Gln Val Ala Ser Asn Leu Glu Lys Lys Gln Lys Lys Phe Asp Gln
                1445                1450                1455

 Leu Leu Ala Glu Glu Lys Ser Ile Ser Ala Arg Tyr Ala Glu Glu
                1460                1465                1470

 Arg Asp Arg Ala Glu Ala Glu Ala Arg Glu Lys Glu Thr Lys Ala
                1475                1480                1485

 Leu Ser Leu Ala Arg Ala Leu Glu Glu Ala Leu Glu Ala Lys Glu
                1490                1495                1500

 Glu Phe Glu Arg Gln Asn Lys Gln Leu Arg Ala Asp Met Glu Asp
                1505                1510                1515

 Leu Met Ser Ser Lys Asp Asp Val Gly Lys Asn Val His Glu Leu
                1520                1525                1530

 Glu Lys Ser Lys Arg Ala Leu Glu Gln Gln Val Glu Glu Met Arg
                1535                1540                1545

 Thr Gln Leu Glu Glu Leu Glu Asp Glu Leu Gln Ala Thr Glu Asp
                1550                1555                1560

 Ala Lys Leu Arg Leu Glu Val Asn Met Gln Ala Met Lys Ala Gln
                1565                1570                1575

 Phe Glu Arg Asp Leu Gln Thr Arg Asp Glu Gln Asn Glu Glu Lys
                1580                1585                1590

 Lys Arg Leu Leu Ile Lys Gln Val Arg Glu Leu Glu Ala Glu Leu
                1595                1600                1605

 Glu Asp Glu Arg Lys Gln Arg Ala Leu Ala Val Ala Ser Lys Lys
                1610                1615                1620

 Lys Met Glu Ile Asp Leu Lys Asp Leu Glu Ala Gln Ile Glu Ala
                1625                1630                1635

 Ala Asn Lys Ala Arg Asp Glu Val Ile Lys Gln Leu Arg Lys Leu
                1640                1645                1650

 Gln Ala Gln Met Lys Asp Tyr Gln Arg Glu Leu Glu Glu Ala Arg
                1655                1660                1665

 Ala Ser Arg Asp Glu Ile Phe Ala Gln Ser Lys Glu Ser Glu Lys
                1670                1675                1680

 Lys Leu Lys Ser Leu Glu Ala Glu Ile Leu Gln Leu Gln Glu Glu
                1685                1690                1695

 Leu Ala Ser Ser Glu Arg Ala Arg Arg His Ala Glu Gln Glu Arg
                1700                1705                1710

 Asp Glu Leu Ala Asp Glu Ile Thr Asn Ser Ala Ser Gly Lys Ser
                1715                1720                1725

 Ala Leu Leu Asp Glu Lys Arg Arg Leu Glu Ala Arg Ile Ala Gln
                1730                1735                1740

 Leu Glu Glu Glu Leu Glu Glu Glu Gln Ser Asn Met Glu Leu Leu
                1745                1750                1755

 Asn Asp Arg Phe Arg Lys Thr Thr Leu Gln Val Asp Thr Leu Asn
                1760                1765                1770

 Ala Glu Leu Ala Ala Glu Arg Ser Ala Ala Gln Lys Ser Asp Asn
                1775                1780                1785

 Ala Arg Gln Gln Leu Glu Arg Gln Asn Lys Glu Leu Lys Ala Lys
                1790                1795                1800

 Leu Gln Glu Leu Glu Gly Ala Val Lys Ser Lys Phe Lys Ala Thr
                1805                1810                1815

 Ile Ser Ala Leu Glu Ala Lys Ile Gly Gln Leu Glu Glu Gln Leu
                1820                1825                1830

 Glu Gln Glu Ala Lys Glu Arg Ala Ala Ala Asn Lys Leu Val Arg
                1835                1840                1845

 Arg Thr Glu Lys Lys Leu Lys Glu Ile Phe Met Gln Val Glu Asp
                1850                1855                1860

 Glu Arg Arg His Ala Asp Gln Tyr Lys Glu Gln Met Glu Lys Ala
                1865                1870                1875

 Asn Ala Arg Met Lys Gln Leu Lys Arg Gln Leu Glu Glu Ala Glu
                1880                1885                1890

 Glu Glu Ala Thr Arg Ala Asn Ala Ser Arg Arg Lys Leu Gln Arg
                1895                1900                1905

 Glu Leu Asp Asp Ala Thr Glu Ala Asn Glu Gly Leu Ser Arg Glu
                1910                1915                1920

 Val Ser Thr Leu Lys Asn Arg Leu Arg Arg Gly Gly Pro Ile Ser
                1925                1930                1935

 Phe Ser Ser Ser Arg Ser Gly Arg Arg Gln Leu His Leu Glu Gly
                1940                1945                1950

 Ala Ser Leu Glu Leu Ser Asp Asp Asp Thr Glu Ser Lys Thr Ser
                1955                1960                1965

 Asp Val Asn Glu Thr Gln Pro Pro Gln Ser Glu
                1970                1975

<210> 2565
<211> 8144
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 116-139, 3058-3093
<223> Unknown base

<400> 2565
 ggatgatgat gatgagacac ctctaaactt ggaacaagtt taagacttta 50

 tgagagaaga aaaaaaatca ccaacaagaa ttgtttgagg aaaaattata 100

 actatcctgt gttcannnnn nnnnnnnnnn nnnnnnnnna aagttgttgg 150

 attttttttt aatgatttct tttttggggg agggaatttt gttgcagttt 200

 tatggtggaa aatgcaaaaa ccagagccag gtgcataatc ttgtaatctg 250

 tggatatccc tggagcagga ctgagtacca gttaaaatac tttttgggga 300

 tacacatgtg agatactaag tacttgcaga agatttttgt ctctcttttt 350

 aaagtctctt tccttggaat attgtgagaa tatttgtggc catttaaggt 400

 ttgtgtgatt ttgctaaaat gcatcaccaa cagcgaatgg ctgccttagg 450

 gacggacaaa gagctgagtg atttactgga tttcagtgcg atgttttcac 500

 ctcctgtgag cagtgggaaa aatggaccaa cttctttggc aagtggacat 550

 tttactggct caaatgtaga agacagaagt agctcagggt cctgggggaa 600

 tggaggacat ccaagcccgt ccaggaacta tggagatggg actccctatg 650

 accacatgac cagcagggac cttgggtcac atgacaatct ctctccacct 700

 tttgtcaatt ccagaataca aagtaaaaca gaaaggggct catactcatc 750

 ttatgggaga gaatcaaact tacagggttg ccaccagcag agtctccttg 800

 gaggtgacat ggatatgggc aacccaggaa ccctttcgcc caccaaacct 850

 ggttcccagt actatcagta ttctagcaat aatccccgaa ggaggcctct 900

 tcacagtagt gccatggagg tacagacaaa gaaagttcga aaagttcctc 950

 caggtttgcc atcttcagtc tatgctccat cagcaagcac tgccgactac 1000

 aatagggact cgccaggcta tccttcctcc aaaccagcaa ccagcacttt 1050

 ccctagctcc ttcttcatgc aagatggcca tcacagcagt gacccttgga 1100

 gctcctccag tgggatgaat cagcctggct atgcaggaat gttgggcaac 1150

 tcttctcata ttccacagtc cagcagctac tgtagcctgc atccacatga 1200

 acgtttgagc tatccatcac actcctcagc agacatcaat tccagtcttc 1250

 ctccgatgtc cactttccat cgtagtggta caaaccatta cagcacctct 1300

 tcctgtacgc ctcctgccaa cgggacagac agtataatgg caaatagagg 1350

 aagcggggca gccggcagct cccagactgg agatgctctg gggaaagcac 1400

 ttgcttcgat ctattctcca gatcacacta acaacagctt ttcatcaaac 1450

 ccttcaactc ctgttggctc tcctccatct ctctcagcag gcacagctgt 1500

 ttggtctaga aatggaggac aggcctcatc gtctcctaat tatgaaggac 1550

 ccttacactc tttgcaaagc cgaattgaag atcgtttaga aagactggat 1600

 gatgctattc atgttctccg gaaccatgca gtgggcccat ccacagctat 1650

 gcctggtggt catggggaca tgcatggaat cattggacct tctcataatg 1700

 gagccatggg tggtctgggc tcagggtatg gaaccggcct tctttcagcc 1750

 aacagacatt cactcatggt ggggacccat cgtgaagatg gcgtggccct 1800

 gagaggcagc cattctcttc tgccaaacca ggttccggtt ccacagcttc 1850

 ctgtccagtc tgcgacttcc cctgacctga acccacccca ggacccttac 1900

 agaggcatgc caccaggact acaggggcag agtgtctcct ctggcagctc 1950

 tgagatcaaa tccgatgacg agggtgatga gaacctgcaa gacacgaaat 2000

 cttcggagga caagaaatta gatgacgaca agaaggatat caaatcaatt 2050

 actaggtcaa gatctagcaa taatgacgat gaggacctga caccagagca 2100

 gaaggcagag cgtgagaagg agcggaggat ggccaacaat gcccgagagc 2150

 gtctgcgggt ccgtgacatc aacgaggctt tcaaagagct cggccgcatg 2200

 gtgcagctcc acctcaagag tgacaagccc cagaccaagc tcctgatcct 2250

 ccaccaggcg gtggccgtca tcctcagtct ggagcagcaa gtccgagaaa 2300

 ggaatctgaa tccgaaagct gcgtgtctga aaagaaggga ggaagagaag 2350

 gtgtcctcag agcctccccc tctctccttg gccggcccac accctggaat 2400

 gggagacgca tcgaatcaca tgggacagat gtaaaagggt ccaagttgcc 2450

 acattgcttc attaaaacaa gagaccactt ccttaacagc tgtattatct 2500

 taaacccaca taaacacttc tccttaaccc ccatttttgt aatataagac 2550

 aagtctgagt agttatgaat cgcagacgca agaggtttca gcattcccaa 2600

 ttatcaaaaa acagaaaaac aaaaaaaaga aagaaaaaag tgcaacttga 2650

 gggacgactt tctttaacat atcattcaga atgtgcaaag cagtatgtac 2700

 aggctgagac acagcccaga gactgaacgg caatctttcc acactgtgga 2750

 acaatgcatt tgtgcctaaa cttcttttgg aaaaaaaaaa tataattaat 2800

 ttgtaagtct gaaaaaaaaa tatttaattt aaaaaaaatt gtaaacttgc 2850

 aataatgaaa aagtgtactt ctgaagaaaa ctacatgaac gtttttgttg 2900

 gtattcaagt cagctagtgt ttataattac tggatattga attaggggaa 2950

 gctcggctgc cctagtaaca aaaccagcaa acgtcctgat gacaacgaag 3000

 tgatgacatt agccattcct tagggtagga ggaacagatg gatcttatag 3050

 acctatgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntaaaaat 3100

 ttagtgacta tggtaagctt ttgttcattt gtttcagact tttttctcct 3150

 gtaaaaaaat agtactgatt aactttttta aaagaaagat tttactgtaa 3200

 atatggattt tttttttttg gtcttatttc tgtccctttc cctggtttgt 3250

 tatcgtaacc tgtagtgcca actctgcttc cagaggggta gtgcaggatg 3300

 aaatgctgac cctgatgttg cttctcattc ataaataagt agaaagttgt 3350

 ttctccagtc ttttgggaac acaggactta aaagtcacat catgtgtaga 3400

 tattacaagc agcattacca agacatggca aaaagagttt gtctgaattg 3450

 taatgttgcg tttgtgaacc tattctggga ttttcagagg tacaaggtta 3500

 gaatgctaca atgttaccac tgtgccttcc aatgtttata tcatcggaaa 3550

 cataacataa tcaaagtggc tgtgatttaa caaaatgatt aaagtgttac 3600

 ctacctgtgt agccgaagta gtgtgcagtg aggcgtttct gaatacatgg 3650

 tcagattttt ggaaaaaaac aaaaacaaaa aaaacaagta aagttcaaaa 3700

 accgtcaaat gagaaaattg caagtagtgt gacagagctg attgattttg 3750

 ttgctttctt gatttttttt tttcaaaatg ggtttactaa aatgtagatg 3800

 acttaactgc ctcctccttc gtctgaaaaa tgccaatatt caatcatcat 3850

 gcagcattat aacaagcctt ataagtccta aagcattaag ttgcactttt 3900

 ttgaggaggg gtagtgcagt atttctctgg ccagtatgaa tgaagtttat 3950

 acttaccata tttgatagaa acatagatca agctatggca cagcgactca 4000

 tcagatagct agctttgacg tctgggcaca attgaaccaa cttccatcgt 4050

 gaatctttat aatgattgac tttggtgtat agtgcagtaa acaaatagtg 4100

 ctcctagtta agtatttgtc agcatccttt tgtctctaac ttgtttctat 4150

 ttttacagcc acacaattct tggcatgtat taagaaaaaa aaaaatccct 4200

 gttcaagtag tttttccacc tatcagcact gagtaaatgc cataaatcca 4250

 ttgaaatggt ctaaatgttc catctgttct cctgttttgc cagttatata 4300

 gtaatgaaat acatttgtaa attttatgca acaaatggca aacgtatcat 4350

 tattttgaaa ttgtgtatgt aaaagttata tttttacatg tagactcttg 4400

 ttattatgtg ttttaataca ttgtatcagt ttttgttttt ttttaaaaac 4450

 tgtggtttaa aaagaagtct catttaaatg aaatagctac aagaatcaga 4500

 attttatgtt catttctgaa aatgtaagaa caaataagat agttaccacg 4550

 tggtcatctt ttacaaaccc ataaacattt tgattagctg tgtgtgtgtt 4600

 gaaaaactgt aaatatgttc agtagcgata aaactaaaat aactttgatt 4650

 tgttgataag ttcctaaaat gtggaggtgg attaaaacct taggagaata 4700

 gcagaaatca aacttcatga aaagttattt tggggctttc ctgtgaaatg 4750

 tatgaacaaa gaggctcaga gaaggacatg gaagacaata atgtatactc 4800

 tctcctcctc cctgaataat gaaaaccatg tgtatttgtt ccctccgtat 4850

 gttaaagatt tccttttagt ggtacattct gcactcattt tgtatagtct 4900

 accaaggcgg gtatccctag gaacaatatt atataggaag caggtatact 4950

 ctgatcacat tcaggataag tgtacagaag aaaatacggt gtttactctt 5000

 tagggaactg gaaacactcc ctgcattgat gtacatttta agaatggcac 5050

 ttttgataca tgttatcata aaggtgctta atagagctga attaaagttt 5100

 ttcaaatctg taaacaaagc aaaaaagtaa attgtagtca tttgattatt 5150

 ttttaaattg gtgctttata ttttgttctc actcagagta aaagctgcaa 5200

 tttattgttc accagctttg atgtattcat tactcagtaa tgcaatacct 5250

 ctattgttga attccctttg gaaataagtg aaaattctaa cggccactga 5300

 aagctgctcg ctaggttttg cttggtggag aaacataatc tgcacctatc 5350

 catattaatt gggttgtatc cccattaaaa aagaaaaaaa gggaatgtgg 5400

 cctttttagt gtgtttttta ttgttgttgt tttgtaatta tcaaacccag 5450

 gtaagatatt ggtatcctgc actggatttt caaatgaagt tcagcagaag 5500

 acagttaaga ttaaagtact atacaaaaat ttcaaaaggg tccatactac 5550

 gctatctgta tgacgacact taggctgggg atctctttca gaaactcgga 5600

 ctttaaaagc aacttggagc agttgatcca cctccacatt caagtaattt 5650

 atgaatatgc agaataggga tctgttcatc tagaaatttt taccatttgt 5700

 cttctgtgta gctgcaagga acactaatgt ttatacaact gtcagtccac 5750

 ccagtggtgc aactggttct gattcagtct tccgattcct ttttattttt 5800

 cactttttcc tatttctgaa tttttttttt tatttgtgat cttgattttg 5850

 atgaggggtt ggggagtggg gagggagtcg aaccaagact tggagttaag 5900

 aggattttca tcttttgcat ccaacaggca gaatatgatc tgtgtccaaa 5950

 agtgaacttg agtcaggaat gaatcaattt cagcataaac aagcacaaaa 6000

 atttagtctg ctggctgact ggaagcaaaa aaagtcaaga tggaatatga 6050

 tgaattccaa cacaatgggg caccaaggcc tttaggcctc tctttttatt 6100

 ttgctttggt tttgtttgtt tttctttaga gacatgctct ttctcatggg 6150

 acttgaagtg gactcatctt tgtgcagtgc tggttttgcc atactcattt 6200

 caagtattat agacatatgt aatggtgaaa atatatgaac tgtggccttt 6250

 ttcattcttg ttacttgtga tgcaattaag tgaagataag gaaaaaaaaa 6300

 aaaaaagcag agatttacca tgtatcagtg cctggctttt tgttataaag 6350

 ctttgtttgt ctagtgctct tttgctataa aatagactgt agtacaccct 6400

 agtaggaaaa aaaaaaaact aaatttaaaa ataaaaaata tatttggctt 6450

 atttttcgca ggagcaatcc ttttatacca tgaatattac aaaaaaattg 6500

 tcagattctg aatatttctt ctttgtagat ttttggaatc attatgagta 6550

 aaagtttgtt actttatttt actatttaaa agatgttatt ttaccatgtg 6600

 ttaccaagat gaaactgtat gggtagcttt tttgtttgtt ttttgttttg 6650

 tttttgtttt tgtttttgtt tttagttgta ggtcgcagcg gggaaatttt 6700

 ttgcgactgt acacatagct gcagcattaa aaacttaaaa aaattgttaa 6750

 aaaaagaaaa aaagggaaaa catttcaaaa aaaaaaaaag ataaacagtt 6800

 acaccttgtt ttcaatgtgt ggctgagtgc ctcgattttt tcatgttttt 6850

 ggtgtatttc tgatttgtag aagtgtccaa acaggttgtg tgctggagtt 6900

 ccttcaagac aaaaacaaac ccagcttggt caaggccatt acctgtttcc 6950

 catctgtagt tattcgatga agtcatgtac atgaccgttc tgtagcaata 7000

 aatgtgccat ttttataaac tgtttctgac acttgtttca tttcattttg 7050

 cattgtccat atagctatga ttctcttctg taagtaaaac gcatctatat 7100

 ttcattttcc aagtgttgga ggtattgaca gcttaacaaa caaaacatac 7150

 aaaaaaaatc acaaaaacaa attgaaaagc aaagcacatg attgatcaag 7200

 gaagagatgc ccttaatgaa aatggaacgg gatgcatgca aaacaaaaag 7250

 aaaactgtct agaggattaa ctaattgaag gaatataatt aatgtgtgtg 7300

 taacactgaa gctatgcatt tgaagagctc tgaactgcac cagtgttttc 7350

 ggttgtgctg caggttgcta agtcaagtca gccttaacct tttgcaccag 7400

 ttggtcggct gtttggcaga acattctcag atcttttcag tcaaaaatct 7450

 aagatgattt attttgtatc actttgttaa aagctgaata ttgttaacta 7500

 cagttaatat taacactgta tttatacttt ctcaaactac acccgcccca 7550

 ccacttctgg ttgcctctgt tgactattaa tccagatgta aacaaccaga 7600

 tgtttttttc taacttgtac aaactgacgt gtgtcaacta tcatggaagg 7650

 aaaaaaatgt acagattaaa attattcagt gttatgtact gtaagttaat 7700

 atttttgtag aatggacatc aatctacttt gcaaaatttg gaggctattt 7750

 caacattgca ctgtagaaat gtaaagtaat gtatgcaatg taaaggaaag 7800

 cccgcggtag ctgagcgctt cataacagaa tgttctaatc aagtacgtgg 7850

 tatttgggga tgtctccaat attgctcttg tattctttct aattgggttt 7900

 agtgactagt tgaaggaaaa tgttataacg ccatttggtt cacatgtgaa 7950

 gtgccctcca tagccaaatg ttgggatttt ttgtatttta ttcgtttttg 8000

 gttaggactg tttgcagata tttaaatttt atgaaatttc caaagatttt 8050

 ggttgataac ccccttttac cttctaaatg atttgagatg ttcttatgtt 8100

 cttactgtgt gttttaaata tatataaaag agccacaagc attt 8144

<210> 2566
<211> 671
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 116-139, 3058-3093
<223> Unknown amino acid

<400> 2566
 Met His His Gln Gln Arg Met Ala Ala Leu Gly Thr Asp Lys Glu
   1               5                  10                  15

 Leu Ser Asp Leu Leu Asp Phe Ser Ala Met Phe Ser Pro Pro Val
                  20                  25                  30

 Ser Ser Gly Lys Asn Gly Pro Thr Ser Leu Ala Ser Gly His Phe
                  35                  40                  45

 Thr Gly Ser Asn Val Glu Asp Arg Ser Ser Ser Gly Ser Trp Gly
                  50                  55                  60

 Asn Gly Gly His Pro Ser Pro Ser Arg Asn Tyr Gly Asp Gly Thr
                  65                  70                  75

 Pro Tyr Asp His Met Thr Ser Arg Asp Leu Gly Ser His Asp Asn
                  80                  85                  90

 Leu Ser Pro Pro Phe Val Asn Ser Arg Ile Gln Ser Lys Thr Glu
                  95                 100                 105

 Arg Gly Ser Tyr Ser Ser Tyr Gly Arg Glu Ser Asn Leu Gln Gly
                 110                 115                 120

 Cys His Gln Gln Ser Leu Leu Gly Gly Asp Met Asp Met Gly Asn
                 125                 130                 135

 Pro Gly Thr Leu Ser Pro Thr Lys Pro Gly Ser Gln Tyr Tyr Gln
                 140                 145                 150

 Tyr Ser Ser Asn Asn Pro Arg Arg Arg Pro Leu His Ser Ser Ala
                 155                 160                 165

 Met Glu Val Gln Thr Lys Lys Val Arg Lys Val Pro Pro Gly Leu
                 170                 175                 180

 Pro Ser Ser Val Tyr Ala Pro Ser Ala Ser Thr Ala Asp Tyr Asn
                 185                 190                 195

 Arg Asp Ser Pro Gly Tyr Pro Ser Ser Lys Pro Ala Thr Ser Thr
                 200                 205                 210

 Phe Pro Ser Ser Phe Phe Met Gln Asp Gly His His Ser Ser Asp
                 215                 220                 225

 Pro Trp Ser Ser Ser Ser Gly Met Asn Gln Pro Gly Tyr Ala Gly
                 230                 235                 240

 Met Leu Gly Asn Ser Ser His Ile Pro Gln Ser Ser Ser Tyr Cys
                 245                 250                 255

 Ser Leu His Pro His Glu Arg Leu Ser Tyr Pro Ser His Ser Ser
                 260                 265                 270

 Ala Asp Ile Asn Ser Ser Leu Pro Pro Met Ser Thr Phe His Arg
                 275                 280                 285

 Ser Gly Thr Asn His Tyr Ser Thr Ser Ser Cys Thr Pro Pro Ala
                 290                 295                 300

 Asn Gly Thr Asp Ser Ile Met Ala Asn Arg Gly Ser Gly Ala Ala
                 305                 310                 315

 Gly Ser Ser Gln Thr Gly Asp Ala Leu Gly Lys Ala Leu Ala Ser
                 320                 325                 330

 Ile Tyr Ser Pro Asp His Thr Asn Asn Ser Phe Ser Ser Asn Pro
                 335                 340                 345

 Ser Thr Pro Val Gly Ser Pro Pro Ser Leu Ser Ala Gly Thr Ala
                 350                 355                 360

 Val Trp Ser Arg Asn Gly Gly Gln Ala Ser Ser Ser Pro Asn Tyr
                 365                 370                 375

 Glu Gly Pro Leu His Ser Leu Gln Ser Arg Ile Glu Asp Arg Leu
                 380                 385                 390

 Glu Arg Leu Asp Asp Ala Ile His Val Leu Arg Asn His Ala Val
                 395                 400                 405

 Gly Pro Ser Thr Ala Met Pro Gly Gly His Gly Asp Met His Gly
                 410                 415                 420

 Ile Ile Gly Pro Ser His Asn Gly Ala Met Gly Gly Leu Gly Ser
                 425                 430                 435

 Gly Tyr Gly Thr Gly Leu Leu Ser Ala Asn Arg His Ser Leu Met
                 440                 445                 450

 Val Gly Thr His Arg Glu Asp Gly Val Ala Leu Arg Gly Ser His
                 455                 460                 465

 Ser Leu Leu Pro Asn Gln Val Pro Val Pro Gln Leu Pro Val Gln
                 470                 475                 480

 Ser Ala Thr Ser Pro Asp Leu Asn Pro Pro Gln Asp Pro Tyr Arg
                 485                 490                 495

 Gly Met Pro Pro Gly Leu Gln Gly Gln Ser Val Ser Ser Gly Ser
                 500                 505                 510

 Ser Glu Ile Lys Ser Asp Asp Glu Gly Asp Glu Asn Leu Gln Asp
                 515                 520                 525

 Thr Lys Ser Ser Glu Asp Lys Lys Leu Asp Asp Asp Lys Lys Asp
                 530                 535                 540

 Ile Lys Ser Ile Thr Arg Ser Arg Ser Ser Asn Asn Asp Asp Glu
                 545                 550                 555

 Asp Leu Thr Pro Glu Gln Lys Ala Glu Arg Glu Lys Glu Arg Arg
                 560                 565                 570

 Met Ala Asn Asn Ala Arg Glu Arg Leu Arg Val Arg Asp Ile Asn
                 575                 580                 585

 Glu Ala Phe Lys Glu Leu Gly Arg Met Val Gln Leu His Leu Lys
                 590                 595                 600

 Ser Asp Lys Pro Gln Thr Lys Leu Leu Ile Leu His Gln Ala Val
                 605                 610                 615

 Ala Val Ile Leu Ser Leu Glu Gln Gln Val Arg Glu Arg Asn Leu
                 620                 625                 630

 Asn Pro Lys Ala Ala Cys Leu Lys Arg Arg Glu Glu Glu Lys Val
                 635                 640                 645

 Ser Ser Glu Pro Pro Pro Leu Ser Leu Ala Gly Pro His Pro Gly
                 650                 655                 660

 Met Gly Asp Ala Ser Asn His Met Gly Gln Met
                 665                 670

<210> 2567
<211> 8018
<212> DNA
<213> Homo sapien

<400> 2567
 cgccgctctg agtccagcct cctactgaga acagtccctc ccttgtgcgg 50

 gtcgcacggc tagccgcagg ttcggccacg tcaaatccat tttctaaaaa 100

 agcagggagc agagctctct cttcgccgcc gacgcagaaa ggagctgggg 150

 aggaaaaagc tgctgccttt tgcgctggag attcgtgggc aaggcttctc 200

 attttcccag gctgcttccc ctcccgggtg aggagcgtcc tgagactaag 250

 gaaagagcct ggaaaatgga gcagacctgg acgagagatt attttgcaga 300

 ggatgatggg gagatggtac ccagaacgag tcacacagca gcttttctta 350

 gtgacactaa agatcgaggc cctccagtgc agtcacagat ctggagaagt 400

 ggtgaaaagg tcccgtttgt gcagacatat tccttgagag catttgagaa 450

 accccctcag gtacagaccc aggctcttcg agactttgag aagcacctca 500

 atgacctgaa gaaggagaac ttcagcctca agctgcgcat ctacttcctg 550

 gaggagcgca tgcaacagaa gtatgaggcc agccgggagg acatctacaa 600

 gcggaacatt gagctgaagg ttgaagtgga gagcttgaaa cgagaactcc 650

 aggacaagaa acagcatctg gataaaacat gggctgatgt ggagaatctc 700

 aacagtcaga atgaagctga gctccgacgc cagtttgagg agcgacagca 750

 ggagacggag catgtttatg agctcttgga gaataagatc cagcttctgc 800

 aggaggaatc caggctagca aagaatgaag ctgcgcggat ggcagctctg 850

 gtggaagcag agaaggagtg taacctggag ctctcagaga aactgaaggg 900

 agtcaccaaa aactgggaag atgtaccagg agaccaggtc aagcccgacc 950

 aatacactga ggccctggcc cagagggaca agagaattga agaactgaat 1000

 cagagcctgg ctgcccagga gaggcttgta gaacagctat ctcgggagaa 1050

 acaacaactg ctacatctgt tggaggagcc aactagcatg gaagtgcagc 1100

 ccatgactga agagttgctg aaacaacaaa agctgaattc acatgagacc 1150

 actataactc agcagtctgt atctgattcc cacttggcag aactccagga 1200

 aaaaatccag caaacagagg ccaccaacaa gattcttcaa gagaaactta 1250

 atgaaatgag ctatgaacta aagtgtgctc aggagtcgtc tcaaaagcaa 1300

 gatggtacaa ttcagaacct caaggaaact ctgaaaagca gggaacgtga 1350

 gactgaggag ttgtaccagg taattgaagg tcaaaatgac acaatggcaa 1400

 agcttcgaga aatgctgcac caaagccagc ttggacaact tcacagctca 1450

 gagggtactt ctccagctca gcaacaggta gctctgcttg atcttcagag 1500

 tgctttattc tgcagccaac ttgaaataca gaagctccag agggtggtac 1550

 gacagaaaga gcgccaactg gctgatgcca aacaatgtgt gcaatttgta 1600

 gaggctgcag cacacgagag tgaacagcag aaagaggctt cttggaaaca 1650

 taaccaggaa ttgcgaaaag ccttgcagca gctacaagaa gaattgcaga 1700

 ataagagcca acagcttcgt gcctgggagg ctgaaaaata caatgagatt 1750

 cgaacccagg aacaaaacat ccagcaccta aaccatagtc tgagtcacaa 1800

 ggagcagttg cttcaggaat ttcgggagct cctacagtat cgagataact 1850

 cagacaaaac ccttgaagca aatgaaatgt tgcttgagaa acttcgccag 1900

 cgaatacatg ataaagctgt tgctctggag cgggctatag atgaaaaatt 1950

 ctctgctcta gaagagaaag aaaaagaact gcgccagctt cgtcttgctg 2000

 tgagagagcg agatcatgac ttagagagac tgcgcgatgt cctctcctcc 2050

 aatgaagcta ctatgcaaag tatggagagt ctcctgaggg ccaaaggcct 2100

 ggaagtggaa cagttatcta ctacctgtca aaacctccag tggctgaaag 2150

 aagaaatgga aaccaaattt agccgttggc agaaggaaca agagagtatc 2200

 attcagcagt tacagacgtc tcttcatgat aggaacaaag aagtggagga 2250

 tcttagtgca acactgctct gcaaacttgg accagggcag agtgagatag 2300

 cagaggagct gtgccagcgt ctacagcgaa aggaaaggat gctgcaggac 2350

 cttctaagtg atcgaaataa acaagtgctg gaacatgaaa tggagattca 2400

 aggcctgctt cagtctgtga gcaccaggga gcaggaaagc caagctgctg 2450

 cagagaagtt ggtgcaagcc ttaatggaaa gaaattcaga attacaggcc 2500

 ctgcgccaat atttaggagg gagagactcc ctgatgtccc aagcacccat 2550

 ctctaaccaa caagctgaag ttacccccac tggccgtctt ggaaaacaga 2600

 ctgatcaagg ttcaatgcag ataccttcca gagatgatag cacttcattg 2650

 actgccaaag aggatgtcag catacccaga tccacattag gagatttgga 2700

 cacagttgca gggctggaaa aagaactgag taatgccaaa gaggaacttg 2750

 aactcatggc taaaaaagaa agagaaagtc agatggaact ttctgctcta 2800

 cagtccatga tggctgtgca ggaagaagag ctgcaggtgc aggctgctga 2850

 tatggagtct ctgaccagga acatacagat taaagaagat ctcataaagg 2900

 acctgcaaat gcaactggtt gatcctgaag acataccagc tatggaacgc 2950

 ctgacccagg aagtcttact tcttcgggaa aaagttgctt cagtagaatc 3000

 ccagggtcaa gaaatttcag gaaaccgaag acaacagttg ctgctgatgc 3050

 tagaaggact agtagatgaa cggagtcggc tcaatgaggc cttacaagca 3100

 gagagacagc tctatagcag tctggtgaag ttccatgccc atccagagag 3150

 ctctgagaga gaccgaactc tgcaggtgga actggaaggg gctcaggtgt 3200

 tacgcagtcg gctagaagaa gttcttggaa gaagcttgga gcgcttaaac 3250

 aggctggaga ccctggccgc cattggaggt gcagctgcag gggatgacac 3300

 cgaagataca agcactgagt tcactgacag tattgaggag gaggctgcac 3350

 accatagtca ccagcaactt gtcaaggtgg ctttggagaa aagtctggca 3400

 actgtggaga cccagaaccc atctttttcc cctccttctc cgatgggagg 3450

 ggacagtaac aggtgtcttc aggaagaaat gctccacctg agggctgagt 3500

 tccaccagca cttagaagag aagaggaaag ctgaggagga actgaaggag 3550

 ctaaaggctc aaattgagga agcaggattc tcctcagtgt cccacatcag 3600

 gaacaccatg ctgagccttt gccttgagaa tgcggagctg aaagagcaga 3650

 tgggagaagc aatgtctgat ggatgggaga tcgaggaaga caaggagaag 3700

 ggcgagttgg ataaccagtc ccagcctcgt gaccctgggc ctcagtcagc 3750

 gtttagccta ccagggtcca cccagcacct gcgctcccag ctgtcacaat 3800

 gcaaacaacg ctatcaagat ctccaggaga agctgctgct atcagaagcc 3850

 actgtctttg ctcaggctaa cgagctggag aaatacagag ttatgcttac 3900

 aggtgaatcc ttggtgaagc aggacagcaa gcagatccag gtggacctcc 3950

 aggacctggg ctatgagact tgtggccgaa gcgagaatga ggctgaacgg 4000

 gaggaaacca ccagtcctga gtgtgaggag cacaacagcc tcaaggaaat 4050

 ggtcctgatg gaggggctgt gctctgagca gggacgccgg ggctcaacac 4100

 tggctagttc ctctgagagg aagcccttgg agaaccagct agggaagcag 4150

 gaagagttcc gggtatatgg aaagtcagaa aacatcttgg tcctacgaaa 4200

 ggacatcaaa gatctgaagg cccagctgca gaatgccaac aaggtcattc 4250

 aaaacctcaa gagccgggtc cggtccctct cagttacaag tgattattcg 4300

 tctagtctgg aaagaccccg gaagctgaga gctgttggca ccttggaggg 4350

 gtcttcacct catagtgtcc ctgatgagga tgaggggtgg ctgtctgatg 4400

 gcactggggc tttctactct ccagggcttc aggccaaaaa ggacctggag 4450

 agtctcatcc agagagtatc ccagctggag gcccagctcc caaaaaatgg 4500

 actagaagag aagctggctg aggagctgag atcagcctcg tggcctggga 4550

 aatatgattc cctgattcag gatcaggccc gggaactgtc ttacctacgg 4600

 caaaaaatac gagaagggag aggtatttgt tatcttatca cccggcatgc 4650

 aaaagataca gtaaaatctt ttgaggatct cctaaggagc aatgacattg 4700

 actactacct gggacagagc ttccgggagc aactcgccca gggaagccag 4750

 ctgacagaga ggctcaccag caaactcagc accaaggatc ataaaagtga 4800

 gaaagatcaa gctggacttg agccactggc cctcaggctc agcagggagc 4850

 tgcaggagaa ggagaaagtg attgaagtcc tgcaggccaa gctggatgct 4900

 cggtccctca caccctccag cagccatgcc ttgtctgact cccaccgctc 4950

 tcccagcagc acctctttcc tgtctgatga actggaagcc tgctctgaca 5000

 tggacatagt cagcgagtac acacactatg aagagaagaa agcttctccc 5050

 agtcactcag attccatcca tcattcgagt cattctgctg tgttgtcttc 5100

 taaaccatca tcaaccagtg catctcaggg ggctaaggcc gaatccaaca 5150

 gcaaccccat cagcttgcca actccccaga atacccccaa ggaggccaac 5200

 caggcccatt caggtgccag cactgttcct cctgcttcca cagctacatt 5250

 gctgagcaac gacttggaag ccgactcttc ctactacctc aactctgccc 5300

 agcctcactc tcctccaagg ggcaccatag aactgggaag aatcctagag 5350

 cctgggtacc tgggcagcag tggcaagtgg gatgtgatga ggcctcagaa 5400

 agggagtgta tctggggacc tatcctcagg ctcctctgtg taccagctta 5450

 actccaaacc cacaggggct gacctgctgg aagagcatct tggtgaaatc 5500

 cggaacctgc gccagcgcct ggaggaatcc atctgcatca atgaccgcct 5550

 acgggagcaa ctggaacacc ggctgacctc tactgctcgt ggaaggggat 5600

 ccacttctaa cttctacagt cagggcctgg agtccatacc tcagctctgc 5650

 aatgagaaca gagtcctcag ggaagacaat cgaagacttc aggctcaact 5700

 gagtcatgtt tccagagagc actcccagga aacagaaagc ctgagggagg 5750

 ctctgctgtc ctctcgatcc caccttcaag agctggaaaa ggagctggag 5800

 caccagaagg tggaaaggca gcagcttttg gaagacttga gggagaagca 5850

 gcaagaggtc ttgcatttca gggaggaacg tctttccctc caggaaaacg 5900

 actccagact gcagcacaag ctggttctcc tgcagcaaca gtgtgaagag 5950

 aaacagcagc tctttgagtc cctccagtca gagctacaaa tctacgaggc 6000

 actttatggc aattccaaga aggggctgaa agcttacagc ctggatgcct 6050

 gtcaccaaat ccctttgagc agtgacctga gccacctggt ggcagaggta 6100

 cgagctctga gagggcagct ggagcagagc attcagggga acaattgtct 6150

 gcgactgcag ctgcaacagc agctggagag cggtgctggc aaagccagcc 6200

 tcagcccctc ctccattaac cagaacttcc cagccagcac tgaccctgga 6250

 aacaagcagc tgctcctcca agattcagct gtgtcccctc cagtccggga 6300

 tgttggtatg aattccccag ctctggtctt ccccagctct gcttcctcta 6350

 ctcctggctc agaaacgccc ataatcaaca gagcaaatgg cttgggtttg 6400

 gatacttctc cagtaatgaa gacccctccc aagctagagg gtgatgctac 6450

 tgatggctcc tttgccaata agcatggccg ccatgtcatt ggccacattg 6500

 atgactacag tgccctaaga cagcagattg cggagggcaa gctgctggtc 6550

 aaaaagatag tgtctcttgt gagatcagcg tgcagcttcc ctggccttga 6600

 agcccaaggc acagaggtgc taggcagcaa aggtattcat gagcttcgga 6650

 gcagcaccag tgccctgcac catgccctag aggagtcagc ttccctcctc 6700

 accatgttct ggagagcggc cctgccaagc acccacatcc ctgtgctgcc 6750

 tggcaaagtg ggagaatcaa cagaaaggga acttctggaa ctgagaacca 6800

 aagtatccaa acaggagcga ctccttcaga gcacaactga gcatctgaag 6850

 aacgccaacc agcagaagga gagcatggag cagttcattg tcagccagct 6900

 aaccagaaca catgatgttt taaagaaggc aaggactaac ttagaggtga 6950

 aatccctaag ggctctgcca tgtactccag ccttgtgacc cttgccttcc 7000

 aggaaccatg caagaagcgc agccaccaga agtccttaaa acagcaggaa 7050

 aggtgggcct gtcccccttt tgtgcagcta cctatctgct gaggagcatc 7100

 tgggcctcat tcctccaagt ccacgggagg gtccagaaga gggagtcaga 7150

 gatgtatcct ggtggagctg ggagaaaggc agaaagcctt tctgacggct 7200

 atggaatacg attagccaag gtccacttgg cccagcacta agaaaaagat 7250

 gcgtagtttg cacagaaggt tttgtgatcc tgcctctcaa cagccccagc 7300

 agcttgggaa ctagcaagag cacatttctt gcctcatcag ctgtcctgag 7350

 atggaaaact cagtgaatat aggaccctga ttccgatgaa aggggcacgt 7400

 ggtcccaatg ctggagctcc tctggcaggt tctaaaagca cactactgag 7450

 cagcggtgcc ctgccggaca ctgctggcgg gggctcagtg agcactactc 7500

 acagatccac acctgaccct gttgggtcga gtcaggctgg gccttggtct 7550

 gcactgtagc acctgtgttc tttgagttca catcatgaat gtggtgactt 7600

 cccagatacc atctcaggct taacctagca catcctattt cttttcttct 7650

 atgatatcca aattggactg acctcacttc aaagttgctg tcccattttg 7700

 tcaccctatc ttatctcggg gaaattgcag actgatggcc agaccaactc 7750

 tgttgaaatt cttgcataga gcaaacctgt gctcattttt aagtggcatg 7800

 ggagaggccc caagcctagt aaagcctagt ctgtgtcttc acagtgctgg 7850

 tagaatgtgt ttgtgtgtat aaatatatga tatagattta tatatgttgc 7900

 taacgccata tattgaaggc caacataact ggtggacagg gtgggtgaca 7950

 gaaaatgaaa gtctttttgg tgattgttaa agcaaaatgt gtataaagaa 8000

 ataaatagtt tttctttc 8018

<210> 2568
<211> 4221
<212> DNA
<213> Homo sapien

<400> 2568
 aattcggcac gagacaaaaa gagaaagaaa atgccgaaac caatcaacgt 50

 aagagtaact acaatggatg ctgagctgga atttgccatt cagcccaata 100

 caactggcaa acaacttttt gaccaggtgg tgaaaacagt tggtttgcgt 150

 gaggtctggt tttttgggct gcagtatgta gacagcaaag gttattctac 200

 atggcttaaa ctaaataaaa aggtaacaca gcaggatgtt aaaaaagaga 250

 atcctttaca gttcaagttt agagctaaat tctttcctga agatgtttct 300

 gaggaattaa ttcaagaaat aacccagaga ctcttcttct tgcaagttaa 350

 agaagccatc ttaaatgatg agatatattg cccgccagaa actgcagttc 400

 ttttggcttc ctatgctgtc caagccaagt atggagatta caataaagag 450

 attcataagc caggctacct ggctaatgat agactcctac cccagcgtgt 500

 attggaacaa cacaaactaa caaaagaaca gtgggaagaa agaatacaga 550

 actggcatga agaacataga ggaatgttaa gggaggattc tatgatggaa 600

 tacctgaaga ttgcacaaga tctagaaatg tatggagtca actattttga 650

 aataaaaaat aaaaaaggaa ctgaattgtg gctaggtgtt gatgctttgg 700

 gtctgaatat ttatgagcat gacgacaagt taacacctaa aattggtttt 750

 ccctggagtg aaatcagaaa tatttcattt aatgacaaaa aatttgttat 800

 aaagccaatc gacaaaaagg cacctgattt tgtgttttat gcacctcgtc 850

 tgagaatcaa taagcggatt ttggccttat gtatgggaaa ccatgaacta 900

 tacatgcgaa gaaggaagcc tgatactatt gaagtacaac agatgaaggc 950

 tcaggctagg gaggagaaac atcagaagca gttggaaagg gcacaattag 1000

 agaatgaaaa gaagaaaaga gaaatagcag aaaaggaaaa ggaaagaata 1050

 gaacgtgaaa aggaagagct aatggaacgt ctaaaacaaa ttgaagagca 1100

 gacaattaaa gctcagaaag aactagaaga acagactcga aaagctctag 1150

 aactggatca agaacgaaaa cgagcaaaag aagaagcaga acgacttgaa 1200

 aaggagcgtc gagctgctga agaggcaaag tctgccatag caaaacaagc 1250

 tgccgaccag atgaagaatc aggagcagct agcagcagaa cttgctgaat 1300

 tcactgccaa gattgcactt ctagaggaag ccaagaagaa aaaggaagag 1350

 gaagcaactg agtggcaaca caaagctttt gcagcccagg aagacttgga 1400

 aaagaccaaa gaagagttaa aaactgtgat gtctgccccc cctccacctc 1450

 caccaccacc agtcattcct ccaacagaaa acgaacatga tgaacacgat 1500

 gagaataatg ctgaagctag tgctgaatta tcaaatgaag gggtaatgaa 1550

 ccatagaagc gaggaagaac gtgtaaccga aacacagaaa aatgagcgtg 1600

 ttaagaagca acttcaggca ttaagttcag aattagccca agccagagat 1650

 gaaaccaaga aaacacaaaa tgatgttctt catgctgaga atgttaaagc 1700

 aggccgtgat aagtacaaga ctctgcgaca gattcgacaa ggcaatacaa 1750

 agcagcgtat cgatgagttt gaagcaatgt gagagctgtt attttgcata 1800

 tatgttcttc ataagctgaa ccaccaacag agaaaagcag gcctttgcag 1850

 atatgatgga atgcatccca ccttgccaaa gcacttacac cagtttgact 1900

 gtgctagcta aaagacaaat ttaaggggag ctcttcaaca ttaaggcagt 1950

 atgatatcat gcttggtttt cttttttctt ttggtccagg gaatggagaa 2000

 tggtgttcca ttgcctcttt tcacattttt tttctttttc tttttttttt 2050

 ctgttgaaga ttaacactaa ttatcacgtc tgacaaatgt gtatgtgtgg 2100

 tttcagttct gtgtacattt taaaggataa tggtgaacat tttaatgggt 2150

 ttcccttgcc ctttccatat ttaacctatt tccacattct ctctcactca 2200

 cattttctca gtgtgccctt ctcttatctg ccatgtccat agccataatt 2250

 ccaccatcat acagatcagg cagtgtttaa aatgatggta ggtagcacag 2300

 tggacagtct ttgatcatca tgtagaatat ggctatgaat caggaaagag 2350

 attagaacat ttaataatgt atgtacagct ggtgcttagt ttttttttaa 2400

 tctaaattta attaccttat tggatatttg atatttggtt atttaatcac 2450

 agtcatcttt aacagcttac actgattggt gttttatctc ctgtgatcct 2500

 ttgatggctt tttttgccta ccatttcaca gaggtttaga cagcagtagt 2550

 agctccctag gagagtttac tgatgaaaca gcctctgcaa gattttaaaa 2600

 gttttgttct tttatagact gatttagaaa aacaaatgat tagttaaaaa 2650

 aagaaaatat acatttgttg gtaactaatg ttatttttta aaacctggac 2700

 ctttctggaa gggcagcata taaaaacatc agtcccgagg aggggacaac 2750

 aatactacct cactactaca tctgtgatga ctggttgttc aaacacaatg 2800

 gagtgtgtaa ggtatatgtt ttataattca taaccatagc ctcgatcatc 2850

 aagaaatact ttcgaaattt cattttcctt cagaatatct taagagtgct 2900

 aaatttttaa ctgccttttt gtcgagtcaa actgtgggat tctgatttgt 2950

 attaaaattg taagctcctc actggtatac tatcatcctg gaggggtgtt 3000

 gtatggctga gcaagagaga gagagaatga gagagagact gtgtgtgtgt 3050

 gtgtgtgtgt gtgtactctg tgtgtgtatg agagagagag agaaatgcta 3100

 accttgtagc atgtgaagaa tgtctgtacc ttgatacgat agttacataa 3150

 tcagtatatt tggtttctag atcactgtgc ttattttgtt tcaatctctg 3200

 actaaaaata cttaaatttg gtttgttaat tcttatttta gaaattataa 3250

 ttttagttta tattaatttc ggttatagct tactgaagaa atctttccag 3300

 ttagaaggag gttctaatat tcacatgttc taatactttg tttattgtaa 3350

 aacagctaaa tttggagata cgtaaagcct tgttttctct gtgtggttca 3400

 gctactttcc atttggtatt acacagtcaa atttacattt atctattaaa 3450

 attgccattt tattaaacat tttcatgcac agtagattca agttgtgtct 3500

 gaaaatatct cttgtgcttt tttgattttg ctgactttaa aaggattaat 3550

 ctgggcagac attatgtaaa agaaaggttg cgtttaatat attttttgaa 3600

 ctttgtagga caaaacatag ctggttaacc ttgaagtgac tgttgtacca 3650

 tggttgtgca catgcttcag aatcctatgg aagagaatat tcctacttgc 3700

 agtacatcaa aggaatggat ggtggaccct actattcatg ttttgagaca 3750

 taaatgttca ctttaaagca attgcataat agataaaaac ctgaactttc 3800

 attggatttt tgttaatttt cctcattttg aattatgtgc actaccatag 3850

 ctacatcagt ttgatacagt attgaaaaat tatcagttat attttgctgt 3900

 ttatgatcta tttgtagatt aggattaaaa tggatttaat ccatttttaa 3950

 ggctgtgtga atttttctaa acaagaacca tttgcaatat ggatttctta 4000

 gagattaaac caattataac ttattagcag tcgcgagcac atgttcatat 4050

 agtcaatgta aaaatacact aatgagtatt tggtaaatcc cagtaggctt 4100

 ttaccattag cataattttg tgttgtacaa ttaagttaca attacatctc 4150

 taattttgga taatattcat tggttaacaa taaagtgaca aaagctcatg 4200

 caaaaaaaaa aaaaaaaaaa a 4221

<210> 2569
<211> 583
<212> PRT
<213> Homo sapien

<400> 2569
 Met Pro Lys Pro Ile Asn Val Arg Val Thr Thr Met Asp Ala Glu
   1               5                  10                  15

 Leu Glu Phe Ala Ile Gln Pro Asn Thr Thr Gly Lys Gln Leu Phe
                  20                  25                  30

 Asp Gln Val Val Lys Thr Val Gly Leu Arg Glu Val Trp Phe Phe
                  35                  40                  45

 Gly Leu Gln Tyr Val Asp Ser Lys Gly Tyr Ser Thr Trp Leu Lys
                  50                  55                  60

 Leu Asn Lys Lys Val Thr Gln Gln Asp Val Lys Lys Glu Asn Pro
                  65                  70                  75

 Leu Gln Phe Lys Phe Arg Ala Lys Phe Phe Pro Glu Asp Val Ser
                  80                  85                  90

 Glu Glu Leu Ile Gln Glu Ile Thr Gln Arg Leu Phe Phe Leu Gln
                  95                 100                 105

 Val Lys Glu Ala Ile Leu Asn Asp Glu Ile Tyr Cys Pro Pro Glu
                 110                 115                 120

 Thr Ala Val Leu Leu Ala Ser Tyr Ala Val Gln Ala Lys Tyr Gly
                 125                 130                 135

 Asp Tyr Asn Lys Glu Ile His Lys Pro Gly Tyr Leu Ala Asn Asp
                 140                 145                 150

 Arg Leu Leu Pro Gln Arg Val Leu Glu Gln His Lys Leu Thr Lys
                 155                 160                 165

 Glu Gln Trp Glu Glu Arg Ile Gln Asn Trp His Glu Glu His Arg
                 170                 175                 180

 Gly Met Leu Arg Glu Asp Ser Met Met Glu Tyr Leu Lys Ile Ala
                 185                 190                 195

 Gln Asp Leu Glu Met Tyr Gly Val Asn Tyr Phe Glu Ile Lys Asn
                 200                 205                 210

 Lys Lys Gly Thr Glu Leu Trp Leu Gly Val Asp Ala Leu Gly Leu
                 215                 220                 225

 Asn Ile Tyr Glu His Asp Asp Lys Leu Thr Pro Lys Ile Gly Phe
                 230                 235                 240

 Pro Trp Ser Glu Ile Arg Asn Ile Ser Phe Asn Asp Lys Lys Phe
                 245                 250                 255

 Val Ile Lys Pro Ile Asp Lys Lys Ala Pro Asp Phe Val Phe Tyr
                 260                 265                 270

 Ala Pro Arg Leu Arg Ile Asn Lys Arg Ile Leu Ala Leu Cys Met
                 275                 280                 285

 Gly Asn His Glu Leu Tyr Met Arg Arg Arg Lys Pro Asp Thr Ile
                 290                 295                 300

 Glu Val Gln Gln Met Lys Ala Gln Ala Arg Glu Glu Lys His Gln
                 305                 310                 315

 Lys Gln Leu Glu Arg Ala Gln Leu Glu Asn Glu Lys Lys Lys Arg
                 320                 325                 330

 Glu Ile Ala Glu Lys Glu Lys Glu Arg Ile Glu Arg Glu Lys Glu
                 335                 340                 345

 Glu Leu Met Glu Arg Leu Lys Gln Ile Glu Glu Gln Thr Ile Lys
                 350                 355                 360

 Ala Gln Lys Glu Leu Glu Glu Gln Thr Arg Lys Ala Leu Glu Leu
                 365                 370                 375

 Asp Gln Glu Arg Lys Arg Ala Lys Glu Glu Ala Glu Arg Leu Glu
                 380                 385                 390

 Lys Glu Arg Arg Ala Ala Glu Glu Ala Lys Ser Ala Ile Ala Lys
                 395                 400                 405

 Gln Ala Ala Asp Gln Met Lys Asn Gln Glu Gln Leu Ala Ala Glu
                 410                 415                 420

 Leu Ala Glu Phe Thr Ala Lys Ile Ala Leu Leu Glu Glu Ala Lys
                 425                 430                 435

 Lys Lys Lys Glu Glu Glu Ala Thr Glu Trp Gln His Lys Ala Phe
                 440                 445                 450

 Ala Ala Gln Glu Asp Leu Glu Lys Thr Lys Glu Glu Leu Lys Thr
                 455                 460                 465

 Val Met Ser Ala Pro Pro Pro Pro Pro Pro Pro Pro Val Ile Pro
                 470                 475                 480

 Pro Thr Glu Asn Glu His Asp Glu His Asp Glu Asn Asn Ala Glu
                 485                 490                 495

 Ala Ser Ala Glu Leu Ser Asn Glu Gly Val Met Asn His Arg Ser
                 500                 505                 510

 Glu Glu Glu Arg Val Thr Glu Thr Gln Lys Asn Glu Arg Val Lys
                 515                 520                 525

 Lys Gln Leu Gln Ala Leu Ser Ser Glu Leu Ala Gln Ala Arg Asp
                 530                 535                 540

 Glu Thr Lys Lys Thr Gln Asn Asp Val Leu His Ala Glu Asn Val
                 545                 550                 555

 Lys Ala Gly Arg Asp Lys Tyr Lys Thr Leu Arg Gln Ile Arg Gln
                 560                 565                 570

 Gly Asn Thr Lys Gln Arg Ile Asp Glu Phe Glu Ala Met
                 575                 580

<210> 2570
<211> 4221
<212> DNA
<213> Homo sapien

<400> 2570
 aattcggcac gagacaaaaa gagaaagaaa atgccgaaac caatcaacgt 50

 aagagtaact acaatggatg ctgagctgga atttgccatt cagcccaata 100

 caactggcaa acaacttttt gaccaggtgg tgaaaacagt tggtttgcgt 150

 gaggtctggt tttttgggct gcagtatgta gacagcaaag gttattctac 200

 atggcttaaa ctaaataaaa aggtaacaca gcaggatgtt aaaaaagaga 250

 atcctttaca gttcaagttt agagctaaat tctttcctga agatgtttct 300

 gaggaattaa ttcaagaaat aacccagaga ctcttcttct tgcaagttaa 350

 agaagccatc ttaaatgatg agatatattg cccgccagaa actgcagttc 400

 ttttggcttc ctatgctgtc caagccaagt atggagatta caataaagag 450

 attcataagc caggctacct ggctaatgat agactcctac cccagcgtgt 500

 attggaacaa cacaaactaa caaaagaaca gtgggaagaa agaatacaga 550

 actggcatga agaacataga ggaatgttaa gggaggattc tatgatggaa 600

 tacctgaaga ttgcacaaga tctagaaatg tatggagtca actattttga 650

 aataaaaaat aaaaaaggaa ctgaattgtg gctaggtgtt gatgctttgg 700

 gtctgaatat ttatgagcat gacgacaagt taacacctaa aattggtttt 750

 ccctggagtg aaatcagaaa tatttcattt aatgacaaaa aatttgttat 800

 aaagccaatc gacaaaaagg cacctgattt tgtgttttat gcacctcgtc 850

 tgagaatcaa taagcggatt ttggccttat gtatgggaaa ccatgaacta 900

 tacatgcgaa gaaggaagcc tgatactatt gaagtacaac agatgaaggc 950

 tcaggctagg gaggagaaac atcagaagca gttggaaagg gcacaattag 1000

 agaatgaaaa gaagaaaaga gaaatagcag aaaaggaaaa ggaaagaata 1050

 gaacgtgaaa aggaagagct aatggaacgt ctaaaacaaa ttgaagagca 1100

 gacaattaaa gctcagaaag aactagaaga acagactcga aaagctctag 1150

 aactggatca agaacgaaaa cgagcaaaag aagaagcaga acgacttgaa 1200

 aaggagcgtc gagctgctga agaggcaaag tctgccatag caaaacaagc 1250

 tgccgaccag atgaagaatc aggagcagct agcagcagaa cttgctgaat 1300

 tcactgccaa gattgcactt ctagaggaag ccaagaagaa aaaggaagag 1350

 gaagcaactg agtggcaaca caaagctttt gcagcccagg aagacttgga 1400

 aaagaccaaa gaagagttaa aaactgtgat gtctgccccc cctccacctc 1450

 caccaccacc agtcattcct ccaacagaaa acgaacatga tgaacacgat 1500

 gagaataatg ctgaagctag tgctgaatta tcaaatgaag gggtaatgaa 1550

 ccatagaagc gaggaagaac gtgtaaccga aacacagaaa aatgagcgtg 1600

 ttaagaagca acttcaggca ttaagttcag aattagccca agccagagat 1650

 gaaaccaaga aaacacaaaa tgatgttctt catgctgaga atgttaaagc 1700

 aggccgtgat aagtacaaga ctctgcgaca gattcgacaa ggcaatacaa 1750

 agcagcgtat cgatgagttt gaagcaatgt gagagctgtt attttgcata 1800

 tatgttcttc ataagctgaa ccaccaacag agaaaagcag gcctttgcag 1850

 atatgatgga atgcatccca ccttgccaaa gcacttacac cagtttgact 1900

 gtgctagcta aaagacaaat ttaaggggag ctcttcaaca ttaaggcagt 1950

 atgatatcat gcttggtttt cttttttctt ttggtccagg gaatggagaa 2000

 tggtgttcca ttgcctcttt tcacattttt tttctttttc tttttttttt 2050

 ctgttgaaga ttaacactaa ttatcacgtc tgacaaatgt gtatgtgtgg 2100

 tttcagttct gtgtacattt taaaggataa tggtgaacat tttaatgggt 2150

 ttcccttgcc ctttccatat ttaacctatt tccacattct ctctcactca 2200

 cattttctca gtgtgccctt ctcttatctg ccatgtccat agccataatt 2250

 ccaccatcat acagatcagg cagtgtttaa aatgatggta ggtagcacag 2300

 tggacagtct ttgatcatca tgtagaatat ggctatgaat caggaaagag 2350

 attagaacat ttaataatgt atgtacagct ggtgcttagt ttttttttaa 2400

 tctaaattta attaccttat tggatatttg atatttggtt atttaatcac 2450

 agtcatcttt aacagcttac actgattggt gttttatctc ctgtgatcct 2500

 ttgatggctt tttttgccta ccatttcaca gaggtttaga cagcagtagt 2550

 agctccctag gagagtttac tgatgaaaca gcctctgcaa gattttaaaa 2600

 gttttgttct tttatagact gatttagaaa aacaaatgat tagttaaaaa 2650

 aagaaaatat acatttgttg gtaactaatg ttatttttta aaacctggac 2700

 ctttctggaa gggcagcata taaaaacatc agtcccgagg aggggacaac 2750

 aatactacct cactactaca tctgtgatga ctggttgttc aaacacaatg 2800

 gagtgtgtaa ggtatatgtt ttataattca taaccatagc ctcgatcatc 2850

 aagaaatact ttcgaaattt cattttcctt cagaatatct taagagtgct 2900

 aaatttttaa ctgccttttt gtcgagtcaa actgtgggat tctgatttgt 2950

 attaaaattg taagctcctc actggtatac tatcatcctg gaggggtgtt 3000

 gtatggctga gcaagagaga gagagaatga gagagagact gtgtgtgtgt 3050

 gtgtgtgtgt gtgtactctg tgtgtgtatg agagagagag agaaatgcta 3100

 accttgtagc atgtgaagaa tgtctgtacc ttgatacgat agttacataa 3150

 tcagtatatt tggtttctag atcactgtgc ttattttgtt tcaatctctg 3200

 actaaaaata cttaaatttg gtttgttaat tcttatttta gaaattataa 3250

 ttttagttta tattaatttc ggttatagct tactgaagaa atctttccag 3300

 ttagaaggag gttctaatat tcacatgttc taatactttg tttattgtaa 3350

 aacagctaaa tttggagata cgtaaagcct tgttttctct gtgtggttca 3400

 gctactttcc atttggtatt acacagtcaa atttacattt atctattaaa 3450

 attgccattt tattaaacat tttcatgcac agtagattca agttgtgtct 3500

 gaaaatatct cttgtgcttt tttgattttg ctgactttaa aaggattaat 3550

 ctgggcagac attatgtaaa agaaaggttg cgtttaatat attttttgaa 3600

 ctttgtagga caaaacatag ctggttaacc ttgaagtgac tgttgtacca 3650

 tggttgtgca catgcttcag aatcctatgg aagagaatat tcctacttgc 3700

 agtacatcaa aggaatggat ggtggaccct actattcatg ttttgagaca 3750

 taaatgttca ctttaaagca attgcataat agataaaaac ctgaactttc 3800

 attggatttt tgttaatttt cctcattttg aattatgtgc actaccatag 3850

 ctacatcagt ttgatacagt attgaaaaat tatcagttat attttgctgt 3900

 ttatgatcta tttgtagatt aggattaaaa tggatttaat ccatttttaa 3950

 ggctgtgtga atttttctaa acaagaacca tttgcaatat ggatttctta 4000

 gagattaaac caattataac ttattagcag tcgcgagcac atgttcatat 4050

 agtcaatgta aaaatacact aatgagtatt tggtaaatcc cagtaggctt 4100

 ttaccattag cataattttg tgttgtacaa ttaagttaca attacatctc 4150

 taattttgga taatattcat tggttaacaa taaagtgaca aaagctcatg 4200

 caaaaaaaaa aaaaaaaaaa a 4221

<210> 2571
<211> 583
<212> PRT
<213> Homo sapien

<400> 2571
 Met Pro Lys Pro Ile Asn Val Arg Val Thr Thr Met Asp Ala Glu
   1               5                  10                  15

 Leu Glu Phe Ala Ile Gln Pro Asn Thr Thr Gly Lys Gln Leu Phe
                  20                  25                  30

 Asp Gln Val Val Lys Thr Val Gly Leu Arg Glu Val Trp Phe Phe
                  35                  40                  45

 Gly Leu Gln Tyr Val Asp Ser Lys Gly Tyr Ser Thr Trp Leu Lys
                  50                  55                  60

 Leu Asn Lys Lys Val Thr Gln Gln Asp Val Lys Lys Glu Asn Pro
                  65                  70                  75

 Leu Gln Phe Lys Phe Arg Ala Lys Phe Phe Pro Glu Asp Val Ser
                  80                  85                  90

 Glu Glu Leu Ile Gln Glu Ile Thr Gln Arg Leu Phe Phe Leu Gln
                  95                 100                 105

 Val Lys Glu Ala Ile Leu Asn Asp Glu Ile Tyr Cys Pro Pro Glu
                 110                 115                 120

 Thr Ala Val Leu Leu Ala Ser Tyr Ala Val Gln Ala Lys Tyr Gly
                 125                 130                 135

 Asp Tyr Asn Lys Glu Ile His Lys Pro Gly Tyr Leu Ala Asn Asp
                 140                 145                 150

 Arg Leu Leu Pro Gln Arg Val Leu Glu Gln His Lys Leu Thr Lys
                 155                 160                 165

 Glu Gln Trp Glu Glu Arg Ile Gln Asn Trp His Glu Glu His Arg
                 170                 175                 180

 Gly Met Leu Arg Glu Asp Ser Met Met Glu Tyr Leu Lys Ile Ala
                 185                 190                 195

 Gln Asp Leu Glu Met Tyr Gly Val Asn Tyr Phe Glu Ile Lys Asn
                 200                 205                 210

 Lys Lys Gly Thr Glu Leu Trp Leu Gly Val Asp Ala Leu Gly Leu
                 215                 220                 225

 Asn Ile Tyr Glu His Asp Asp Lys Leu Thr Pro Lys Ile Gly Phe
                 230                 235                 240

 Pro Trp Ser Glu Ile Arg Asn Ile Ser Phe Asn Asp Lys Lys Phe
                 245                 250                 255

 Val Ile Lys Pro Ile Asp Lys Lys Ala Pro Asp Phe Val Phe Tyr
                 260                 265                 270

 Ala Pro Arg Leu Arg Ile Asn Lys Arg Ile Leu Ala Leu Cys Met
                 275                 280                 285

 Gly Asn His Glu Leu Tyr Met Arg Arg Arg Lys Pro Asp Thr Ile
                 290                 295                 300

 Glu Val Gln Gln Met Lys Ala Gln Ala Arg Glu Glu Lys His Gln
                 305                 310                 315

 Lys Gln Leu Glu Arg Ala Gln Leu Glu Asn Glu Lys Lys Lys Arg
                 320                 325                 330

 Glu Ile Ala Glu Lys Glu Lys Glu Arg Ile Glu Arg Glu Lys Glu
                 335                 340                 345

 Glu Leu Met Glu Arg Leu Lys Gln Ile Glu Glu Gln Thr Ile Lys
                 350                 355                 360

 Ala Gln Lys Glu Leu Glu Glu Gln Thr Arg Lys Ala Leu Glu Leu
                 365                 370                 375

 Asp Gln Glu Arg Lys Arg Ala Lys Glu Glu Ala Glu Arg Leu Glu
                 380                 385                 390

 Lys Glu Arg Arg Ala Ala Glu Glu Ala Lys Ser Ala Ile Ala Lys
                 395                 400                 405

 Gln Ala Ala Asp Gln Met Lys Asn Gln Glu Gln Leu Ala Ala Glu
                 410                 415                 420

 Leu Ala Glu Phe Thr Ala Lys Ile Ala Leu Leu Glu Glu Ala Lys
                 425                 430                 435

 Lys Lys Lys Glu Glu Glu Ala Thr Glu Trp Gln His Lys Ala Phe
                 440                 445                 450

 Ala Ala Gln Glu Asp Leu Glu Lys Thr Lys Glu Glu Leu Lys Thr
                 455                 460                 465

 Val Met Ser Ala Pro Pro Pro Pro Pro Pro Pro Pro Val Ile Pro
                 470                 475                 480

 Pro Thr Glu Asn Glu His Asp Glu His Asp Glu Asn Asn Ala Glu
                 485                 490                 495

 Ala Ser Ala Glu Leu Ser Asn Glu Gly Val Met Asn His Arg Ser
                 500                 505                 510

 Glu Glu Glu Arg Val Thr Glu Thr Gln Lys Asn Glu Arg Val Lys
                 515                 520                 525

 Lys Gln Leu Gln Ala Leu Ser Ser Glu Leu Ala Gln Ala Arg Asp
                 530                 535                 540

 Glu Thr Lys Lys Thr Gln Asn Asp Val Leu His Ala Glu Asn Val
                 545                 550                 555

 Lys Ala Gly Arg Asp Lys Tyr Lys Thr Leu Arg Gln Ile Arg Gln
                 560                 565                 570

 Gly Asn Thr Lys Gln Arg Ile Asp Glu Phe Glu Ala Met
                 575                 580

<210> 2572
<211> 4319
<212> DNA
<213> Homo sapien

<400> 2572
 gggtggtggg accagcagtg ggggcagcag caccaactcc ctgactgggt 50

 cccggccccc caaggctcgg cccactattc tcagctcagg gctgccagag 100

 gaacccgacc agaacctgtc cagccctgag gaggtgttcc actctggcca 150

 ctcccgcaac tccagctatg ccagccagca gtccaagatc tccggctaca 200

 gcacagagca ctcgcgctcc tccagcctct cagacctgac gcaccgccgc 250

 aacacgtcca ccagcagcag cgcctctggg ggccttggca tgaccgtgga 300

 gggccctgag ggcagtgagc gggagcaccg gcccccggag aagccgccgc 350

 ggccaccccg gcccctgcat ctgtccgatc gctctttcag gcggaagaag 400

 gactcggtgg agagccaccc gacctgggtg gacgacacgc ggatcgatgc 450

 ggatgccatc gtggagaaga tcgtgcagag ccaggacttc acagatggca 500

 gcaacaccga ggacagcaac ctccggctgt tcgtgagccg cgatggctct 550

 gccacgctga gcggcatcca gcttgccacc aggtagggca ggcttaggga 600

 ggggtcgtcg gggcggctgg ggcttggggg tgagagcaga gtccccacag 650

 tccactcacc tggccttgaa cgccaaatct tgtcgccaca gtgtgaccct 700

 gggcctgtca tgtctctgaa cctccctttc cccatctgtc aggctgtgtg 750

 gacaccacca cctcacctgg gagcctgggg cagtgagggc acggacaggt 800

 tcggtggttt cccacagttc acaaggtcac ctccagcaat gcctggtgca 850

 gggctcagca catggcaggg gcctcacacg catttattta gaaccctccc 900

 ttctacttcc tcccagctcc agggactcgg gaagaatggt ggtggtgatg 950

 cctcatgggt ttactgaaca aatctttccc tagcaccagc taggcactag 1000

 gccctaagtg aaggcctggt tcaatgcagg ctgctgccta cacagcatcc 1050

 acagatggca ggggtagatg ggaccaaagt tgcgggaacg acagtttata 1100

 gagtgctgcg tcacagacat tcatttggag catgttgact atgtgcctgg 1150

 ctctccatgt gctttggcta accaaatgaa tgagcgagtg agcgaatgag 1200

 cttcccacag gcgggctgct gagggcaggt ggggagcccg cctaacatcc 1250

 acatccccag ggaagaggcg tggccaggcc gctgcgcaga ggctaccctc 1300

 tcaagctgct ctgctgactc ctgctggcca cggcctggaa tggcagccat 1350

 cacctcccag tagcctcctg ggctgctctg gggtgggggt gagggggcgg 1400

 tgagcaagaa ggaaactgag gggctggctt ccttatgggt ttgtaaacac 1450

 acccctccct ggccccctct gaaaatgagg aagcatcttg gggaaagaaa 1500

 ccaatctggt tgggagcgag atcacagcag agctacatgc tgagccccga 1550

 gagtccccga ctccagggct gggcctgggc tcggcaggga aaggagctga 1600

 ccaggtttcc tgacttccca ctgccctctt ggtcaccctc acatccctct 1650

 gagcctcagt ttcttcacct gtcaagtggg gcaggatgca gtgactccct 1700

 gccgaggtga ccgtgaggat ggggtggcac agccagatgt gcccggaagg 1750

 gctctgcagg ccccacagac tctgatgctt actatctgtg tcactgtggg 1800

 caagggactt accatcgctg gggcacggtt ttagcccctt tgcaacacag 1850

 ggctggttaa cagtacctgc ttgtgaaaca cctccagagg cctggtccag 1900

 tggagcgctc aggaaatggg gtatcgaggg ggacatgctg acctgtctct 1950

 cacctgcagg gtctcttctg gggtctacga gccagttgtg attgaaagcc 2000

 attgaggagc aggtgtccgg gctggagaag agtcctgctt tctctggagt 2050

 ccagacctgt atcattccat gaggaacttt ccccttcaga tcacctctgc 2100

 gccacatctc atccatgcct cctccatgca ctccagtcca cactccccgt 2150

 agcatcattc cattgcccct cctatccatg ctgggaccct cctggcccac 2200

 caaggcccag gcaccactgt gaatattctc ctctgaacca ctagagggca 2250

 ggccaggcag gccaggcggg cccgtgcagc ttgtgggcaa gaaggagctg 2300

 gcaaggaccg gcgctgctgg agactgaccc agccctctgg ctgaggacat 2350

 gcagcagctc ctaaatgtag agatgcctgt ggctgagggg gcctctctac 2400

 ctgtgtcccc actcactcca ggagcactgg ctttggtcac gtcttagcag 2450

 cagggccttg ctccgttgtt cccttgccct ggtggtgggg gggccagacc 2500

 gcctccggaa tcctgccacc tgtgactgtc tgactgctta gtgcttcagc 2550

 tgtcccttcc ttgtgtcctg ggggacctgc tggcggcctc ttcctgggag 2600

 ccatgacctc agaccccacc cacactccag atcgagaccc ctgcctcccc 2650

 ccggcaaatg tcctcccgct gccttgcagc ctgcactttg cacatgctca 2700

 cccccagcac agtcccactg gcccctcacc tccccttccc tgagctcctt 2750

 cccaaggact cctggtcact gcctgctgtg cagtcagagg cccagggtcc 2800

 agcagcccgg cgggaacggg tgctgcctct tcctccagtt agctccagct 2850

 caggtctgag acccgtgctg agaaaggtct gagcaccgac cgtgccctct 2900

 gcccagggct gggtcctgag cagctggttt tcctgcagga aggttggagc 2950

 aagcaaagtc cttctctgcc ctcagggtca gctgcccaga ctggggcgga 3000

 tgccagagag gcaggtgggc tgtggctgga ctggtccgga gctggcttcc 3050

 ttaccagaaa agcctcagcc ttcctctgga agcatccccc gttctgggca 3100

 agggggaagg gctcctttaa ggggtgtgct ttcccagtgg ggagcagtct 3150

 ggccctgccc cctactaaag cctctgctct cagcactttc ccccaagtcc 3200

 ttgtaacttg cttgaaggtg ggttctggct gccagccagt ccctggacaa 3250

 actctcctgc cccttttaaa tttcactcat tttgtataaa cccagcaggc 3300

 tggtgtttac ttagccctgt agcttttttc attttttctt tccgtctttc 3350

 ttcttgagtt cacggttcaa tattgcctcc tcgccctggt gaggggaggt 3400

 gctgcttttc tgccccacct gccggctggt tccagcagcg ctggggccca 3450

 gctggggggc cgggatgggg gcttctctct ctgggagggg tgcaggtgcc 3500

 ctccccaggc tgggagggtt ccttccctag ctccccatct gcccccgctg 3550

 gtgagagttg ggcttcttgg tcttggaact ccctggcatt gggaacagag 3600

 catttccagc atttgttgtt gttgttttac tcacctaacc cttagaaaat 3650

 gaatgttaga aggtgcctgc cgaggcggga cagagtgttt gctcgcgctg 3700

 gagaaggctc tgctcagccc tgagagtccc ttcctgcccc accgatactg 3750

 gcactttaaa aaggaagctg accgcacagt gtccagacga attggccccc 3800

 agaagatggg gagttctgtc ctgcccttct gtgtctgcgt gacctcaccc 3850

 agcctaggag ggaggtgcat tcagggtaga tttgcctctc attcaaagtt 3900

 ctggggcttt gggcggaaaa cagccagctt tggcgctgtt ggggagactc 3950

 ctccagacca ggaaccccag aaggagacag agcctgccac atcctcccac 4000

 gccaggccct gggccagggt gattggactg agaatttggc cacaaccaaa 4050

 ttgatgctgg ctggaaccag aggccagaaa gcctggcctt gtccccatgt 4100

 gggagccctg tcctcagccc tcttgtcccc ttgagctcag tgaattccca 4150

 ccaggtgccc acagctcctg gacttcaaat tctatatatt gagagagttg 4200

 gagagtatat cagagatatt tttggaaagg agttggtcta tgcaatgtca 4250

 gtttggaatc ttcttgaaag tttaatgttt ttattaggag atttaaagaa 4300

 aataaaggtc tacaatatc 4319

<210> 2573
<211> 3655
<212> DNA
<213> Homo sapien

<400> 2573
 gttggagcgg cgctgctcgg ccgcggacac acgagggacg cgcccgagga 50

 gctgcaggtg gcagcccagg cggtccgaac ccgtcggccg gccgagcctg 100

 gagtattgcc taagtgtaat cttgaacatg ggcggtgctg tgagtgctgg 150

 tgaagacaat gaagagctga tagataattt gaaagaagca cagtatatcc 200

 ggactgagct ggtagagcag gctttcagag ctatcgatcg tgcagactat 250

 tatcttgaag aatttaaaga aaatgcttat aaagacttgg catggaagca 300

 tggaaacatt cacctctcag ccccgtgcat ctactcggag gtgatggaag 350

 ccctagatct gcagcctgga ctctcgtttc tgaacctggg cagtggcact 400

 gggtatctca gctccatggt gggcctcatt ctaggtcctt ttggtgtgaa 450

 ccatggggtg gaacttcact cagatgtgat agagtatgca aagcagaaac 500

 tggacttctt catcagaaca agtgatagtt ttgacaagtt tgacttctgt 550

 gaaccttcct ttgttactgg gaattgcctg gagatttctc cggattgttc 600

 tcagtatgat cgtgtatact gtggggctgg cgtgcagaaa gagcatgaag 650

 agtacatgaa gaatcttctc aaagtgggag ggatccttgt catgccactg 700

 gaagagaagt tgactaagat aacacgcaca ggtccttcag cttgggaaac 750

 caaaaagatt cttgctgttt cttttgctcc tctgatccag ccctgccatt 800

 cagagtcagg aaaatcaaga cttgtccagt taccaccagt ggcagttcgc 850

 agcctccagg acttggctcg catcgccatc cggggcacca ttaaaaagat 900

 tattcatcag gaaactgtga gcaaaaacgg aaacggacta aagaacaccc 950

 ccaggtttaa acgaaggaga gttcgccgcc gtcgaatgga aacgattgtc 1000

 tttttggaca aagaagtctt tgccagtcgg atttccaacc cctcagatga 1050

 caacagctgt gaagacttgg aagaggaacg gagggaagaa gaagagaaga 1100

 ccccgccgga aacaaagcca gaccccccag tgaacttcct acgccagaag 1150

 gtcctgagcc tccctctgcc agatcccctg aaatactact tgctttatta 1200

 cagagaaaaa taagtctcct gtttgaaagg gggaaatagg aagagcagat 1250

 tgctgagtgt gaagttcgtg ctgcctgtgt gctgttgaag ggtcacctgg 1300

 aggcagacgt tgtggggaag ggaactgctg ggctcatcca caccatggtt 1350

 ttcttctagt tcctgattga cctctaaaat tctattcagt tgtatgattt 1400

 gtttacatag ttccacaaga ccttcattgc atagaagatt gttttcccaa 1450

 agtggagaga atcttcatag agaaaaagag aaggctgttt ctttttcggc 1500

 tctgacgaaa cactgaagtc tgcgtaagag agactgtttg atgaccgtcc 1550

 ctcatgcaac atgcacggta ctcactaaaa atgaaaactg aagtggaaac 1600

 taacctgtgt tgcttataaa gtgtgaaagc acaagcttat aaatgtataa 1650

 aatcttttct gggtgtgacg cacctgcgtc caagtttgaa tttttatgat 1700

 atgtaccact taattactgg cactgagtat cactgaattt cttagttttc 1750

 tagtggggaa acattattga gaagccctcc cttattttaa gtaagttgat 1800

 taaatcttat gtgagttgcc agttgtaatt tttcaaagga aaaattttga 1850

 tggggtggag gaatgaattg ccagataatc tttctggaat tccgagagaa 1900

 ttccaaagag ggtttttttt tttttttttt taggacatct tttgatacct 1950

 ttaaaagaac cactgtcaag taatccttaa aaaaatatct tggaaaagga 2000

 aacagatttt ttcctgtgtg taagcaataa gtgaagttac atttgcccta 2050

 accctaggga tgattcttta cccagtttta aagcccatca tggtattcta 2100

 aggtgttgac accctccatc ctcagagcag gtcgaaaata ttaaatagac 2150

 tggggactct atgatgggca gcctgtgctt tttgacttca gtttgctatt 2200

 tttctgtgat cacattagta ctgattcata gattctatct tttataattc 2250

 tggagaaaaa gatttgttag ttttgtaatt tttttgtaag accaaatgta 2300

 tgtattttag tagctccatt gcatgagaag agtgtaactc acactgactt 2350

 gtgatatcag ccttctctgg gccttgtgtg tggagagctt tctatcttac 2400

 caagtggtag ggctaaaaga acaacagcct ttttggtagt cacatagcag 2450

 aatgatcaga gttacattgc ttattccaaa acattggttc tttttaaaac 2500

 attttttttt acccaaagaa aagaataata gaaattacta acaataaata 2550

 taaattcaga gtgttgatat aggattcagt atccagagtt tatttttaat 2600

 cttaatcctc agcttcttgg gagttgctgg gcttcagtgt ctctgtggtt 2650

 tcaccagctt agcttgagct ctggttattt tggatctttt ctgctttttt 2700

 taagtaactg agtcattttt accacacagt ccagtttgca tgtatagcta 2750

 ggaaacatgt attgctctag attgggcagt ttaagtcatt ttaaagaaag 2800

 ttagttcata gttgttgcct tttaactcat agtcaagctt cagtctttca 2850

 aagagaaatg tgtgattttc atttacttgc tgatattttg tagtttggag 2900

 atccttgtgg gcattattct aactgatacg tagacactta cttggaaatt 2950

 tttggacatt atattaaatg agtgctatct gtgaaattgg ttatattagg 3000

 tggcttgact aatgtttttt ctataattgt atatggactg catttttaaa 3050

 aaaaccgcat ttgcctttat gctagattgt aaaaaattat attagaatgc 3100

 ataagacatg tttttccttc atatgctaga cttttcctag catttcgtat 3150

 ttctgtgttg tcagtgtgtg atttttaaac cggaatttgg tttaaaaaaa 3200

 atctggtggt aatatatgtg agaaatactt tggtgtttac cttatgaaaa 3250

 taaaggattg taagtaaagt ttcctgcgca ccttatacca gaattcagta 3300

 taatacacta ctttctgttt tcaaacagat aaatcataat atagtctgta 3350

 ttatctgtaa gatctgtctt gtaaaccaca ttcttgacaa ctatttgctt 3400

 ttgagtagtt tgtattttaa tatgtgactt ttgtcttgaa aagtagtaaa 3450

 gccatagact tgtgcaaaac aagtttcaag tttatagata ttaagtttgt 3500

 aatgtgagca tcaaatgtgt atgtaaaaat actttttacc agtctggaac 3550

 ttgggaaaat ccagggaatt tgaaacatag attttaatga gctggtaaac 3600

 acaaatcatg tcaataaagg tagtcaggat attttatcct tagcattgct 3650

 tctgc 3655

<210> 2574
<211> 361
<212> PRT
<213> Homo sapien

<400> 2574
 Met Gly Gly Ala Val Ser Ala Gly Glu Asp Asn Glu Glu Leu Ile
   1               5                  10                  15

 Asp Asn Leu Lys Glu Ala Gln Tyr Ile Arg Thr Glu Leu Val Glu
                  20                  25                  30

 Gln Ala Phe Arg Ala Ile Asp Arg Ala Asp Tyr Tyr Leu Glu Glu
                  35                  40                  45

 Phe Lys Glu Asn Ala Tyr Lys Asp Leu Ala Trp Lys His Gly Asn
                  50                  55                  60

 Ile His Leu Ser Ala Pro Cys Ile Tyr Ser Glu Val Met Glu Ala
                  65                  70                  75

 Leu Asp Leu Gln Pro Gly Leu Ser Phe Leu Asn Leu Gly Ser Gly
                  80                  85                  90

 Thr Gly Tyr Leu Ser Ser Met Val Gly Leu Ile Leu Gly Pro Phe
                  95                 100                 105

 Gly Val Asn His Gly Val Glu Leu His Ser Asp Val Ile Glu Tyr
                 110                 115                 120

 Ala Lys Gln Lys Leu Asp Phe Phe Ile Arg Thr Ser Asp Ser Phe
                 125                 130                 135

 Asp Lys Phe Asp Phe Cys Glu Pro Ser Phe Val Thr Gly Asn Cys
                 140                 145                 150

 Leu Glu Ile Ser Pro Asp Cys Ser Gln Tyr Asp Arg Val Tyr Cys
                 155                 160                 165

 Gly Ala Gly Val Gln Lys Glu His Glu Glu Tyr Met Lys Asn Leu
                 170                 175                 180

 Leu Lys Val Gly Gly Ile Leu Val Met Pro Leu Glu Glu Lys Leu
                 185                 190                 195

 Thr Lys Ile Thr Arg Thr Gly Pro Ser Ala Trp Glu Thr Lys Lys
                 200                 205                 210

 Ile Leu Ala Val Ser Phe Ala Pro Leu Ile Gln Pro Cys His Ser
                 215                 220                 225

 Glu Ser Gly Lys Ser Arg Leu Val Gln Leu Pro Pro Val Ala Val
                 230                 235                 240

 Arg Ser Leu Gln Asp Leu Ala Arg Ile Ala Ile Arg Gly Thr Ile
                 245                 250                 255

 Lys Lys Ile Ile His Gln Glu Thr Val Ser Lys Asn Gly Asn Gly
                 260                 265                 270

 Leu Lys Asn Thr Pro Arg Phe Lys Arg Arg Arg Val Arg Arg Arg
                 275                 280                 285

 Arg Met Glu Thr Ile Val Phe Leu Asp Lys Glu Val Phe Ala Ser
                 290                 295                 300

 Arg Ile Ser Asn Pro Ser Asp Asp Asn Ser Cys Glu Asp Leu Glu
                 305                 310                 315

 Glu Glu Arg Arg Glu Glu Glu Glu Lys Thr Pro Pro Glu Thr Lys
                 320                 325                 330

 Pro Asp Pro Pro Val Asn Phe Leu Arg Gln Lys Val Leu Ser Leu
                 335                 340                 345

 Pro Leu Pro Asp Pro Leu Lys Tyr Tyr Leu Leu Tyr Tyr Arg Glu
                 350                 355                 360

 Lys


<210> 2575
<211> 3275
<212> DNA
<213> Homo sapien

<400> 2575
 gtactacctt cggtctaggc agcggaggca gccgcgaccc caggaaaccg 50

 aggaaatgaa gacgcgaagg actacccgcc ttcagcagca gcactcagag 100

 cagcctccgc tacagccgtc tcctgttacg accaggagag ggctgcggga 150

 ctctcattcc tctgaagagg atgaagcatc ttcccaaact gatttaagcc 200

 aaacgatctc aaagaaaact gtcaggagca tacaagaggc tccagtgagt 250

 gaagatcttg taatcaggtt acgtcgaccc cctctaagat gcccaagata 300

 tgaagccacc agtgtccaac agaaggtcaa tttctctgaa gaaggagaaa 350

 ctgaagaaga tgatcaagac agctctcaca gcagtgtcac tactgttaag 400

 gccagatcca gggattctga tgaatctgga gataaaacca ccagatcatc 450

 tagtcaatat atagaatcat tttggcagtc atcacaaagt caaaacttca 500

 cagctcatga taagcaacgt tcagtgctaa gctcaggata tcaaaaaact 550

 ccccaggaat gggccccaca aactgcaaga ataaggacca ggatgcaaaa 600

 tgacagcatt ctgaaatcag agcttggaaa ccagtcacca tcaacctcca 650

 gccgacaagt gactggacaa ccccaaaatg catcttttgt caagaggaac 700

 cggtggtggc tacttcctct gatagctgct cttgcctctg ggagtttttg 750

 gttctttagt actcctgagg tagaaaccac tgctgttcaa gagttccaga 800

 accagatgaa tcaacttaag aataagtacc aaggtcaaga tgagaagctg 850

 tggaaaagga gccaaacatt cctggaaaaa catcttaata gctcccatcc 900

 tcggtctcag cctgctatct tactgctcac tgctgcccga gatgctgaag 950

 aagcacttag gtgtctgagt gaacaaattg ctgatgccta ttcttctttt 1000

 cgtagtgtcc gtgccatccg gattgatggg acagataaag ctactcaaga 1050

 cagtgatact gtcaaactag aggtagacca agaactgagc aatggattta 1100

 agaatggcca gaatgcagct gtggtacacc gctttgagtc atttcccgca 1150

 ggctctactt tgatcttcta caaatattgt gaccatgaaa acgcagcctt 1200

 caaagatgta gccttagtcc tgactgtctt attggaggaa gagacacttg 1250

 gaacaagtct aggcctaaag gaagttgaag aaaaagtaag agattttctt 1300

 aaagtcaagt tcaccaattc taacacaccc aactcctaca atcatatgga 1350

 cccagacaaa ctgaatggcc tctggagccg tatttctcac ttagttctgc 1400

 ctgtgcaacc tgaaaatgcc ctgaaaaggg gcatctgctt ataagaagtg 1450

 agagagaaga aaaatcatgt cccaagttct gagaattgtt cacactttct 1500

 aaccagagac agaattcaga gctctttttg aaagaactag tttcttttta 1550

 aagaagttaa gtgcttacat aaacatggaa catataaatc attcattcaa 1600

 cctaattatc tgtgatatga gagaatcatt tcagtttcca ttgagagctc 1650

 tgttaaaggt atcttaggag tgcagattat atgcagttcc ttagagaatc 1700

 tgttttgatt ctgggctgag ttattacaat tatggtatga ccagtgagag 1750

 cgatttgtgt cctttcttat gaaccttcct gattttttaa cttagatttc 1800

 tcactaagtt tcctgagtta ttagtaagat tgctccctaa atgtaaccag 1850

 ggatttttcc attatgttcc cttttatacc atttaggtgt gagttcctta 1900

 gcttctgcct ataggaacat aagtaatgaa aggtcatcta ggtgtgtgtt 1950

 tggaattttt ttcttttgtt ttttggaaaa tggaaagaac aaggcaagga 2000

 aggaaaatta atggggaagc tgaagggagg aaatgttaca gtaatccact 2050

 gagatgtagt ttagtcaaac ataggtatat gaactgttaa tcttggtgga 2100

 ttccgttggg atttgttttt tacatctcct ttttccttcc ttgaagaaaa 2150

 attcttggct gtcccaagga ttcttcatgt atattgcaaa atttaatata 2200

 tttgttcact tgagtcttaa gagtaggtca ggccaaggca ggtggatcac 2250

 ctgaggtcag aagttcaaga ccagcctggc caacatggtg aaaccccctc 2300

 tctactaaaa atacaaaaat tagctgggcg tggtggtgca tgcctgaaat 2350

 cccagctact tgggaggctg aggcaggaga attgcttgaa cccgggaggc 2400

 ggaggttgca gtaagccgag accatgctta ttgccctcca gtctgggcaa 2450

 caaaaatgaa actccgtctc aaaaaaaaaa aagtaggtca attcgtaaca 2500

 gtttattttg gacacaccct gaagcttttg ttttgaatta agaaatgagt 2550

 ttcaggaatt gacaaaccat ttgttaacca gctgtcctgg gctattgaag 2600

 aagatttcat tttccgcgca tccacttgtt gcagtccaag tcctctagtg 2650

 caacgccata gcaaatataa agatttacta tgcacgtgat acattttatg 2700

 gagtgcctca agccaagata gtgaatttat atgaagggtg tgaaatgtat 2750

 ttctttacta ctatagtagt ttagttataa ctttgcatct ataattgagc 2800

 tttctcatct gtcaaatgct atggttttct taaaatgtta caattctaga 2850

 tctatccacc ttgttttttt attgtctaca aaccattaaa tgtaaatatt 2900

 gtttttagag tcagtcattg gctttgtcat ttaccctttg agagttccac 2950

 aagtggtagt agagtggttt aacgtctttc ctctagtact accagtattc 3000

 ataaatgtat accccttact gtaatttgtt cctcttagaa gtcagatcat 3050

 ctgatttata gaggattatg aaaaccagag tttttgaaaa ggcttatttt 3100

 atacatacgt attatataga gaaacaaatg tttttattaa atgtttcatt 3150

 gacccaagta atttaaaagt aatatgttac ctatgtcttt caggaaaaat 3200

 aattatagca gctgatctgt aaatgacttt aaaagctatt ttagtaattt 3250

 aaataaattt actttcttgg tttat 3275

<210> 2576
<211> 462
<212> PRT
<213> Homo sapien

<400> 2576
 Met Lys Thr Arg Arg Thr Thr Arg Leu Gln Gln Gln His Ser Glu
   1               5                  10                  15

 Gln Pro Pro Leu Gln Pro Ser Pro Val Thr Thr Arg Arg Gly Leu
                  20                  25                  30

 Arg Asp Ser His Ser Ser Glu Glu Asp Glu Ala Ser Ser Gln Thr
                  35                  40                  45

 Asp Leu Ser Gln Thr Ile Ser Lys Lys Thr Val Arg Ser Ile Gln
                  50                  55                  60

 Glu Ala Pro Val Ser Glu Asp Leu Val Ile Arg Leu Arg Arg Pro
                  65                  70                  75

 Pro Leu Arg Cys Pro Arg Tyr Glu Ala Thr Ser Val Gln Gln Lys
                  80                  85                  90

 Val Asn Phe Ser Glu Glu Gly Glu Thr Glu Glu Asp Asp Gln Asp
                  95                 100                 105

 Ser Ser His Ser Ser Val Thr Thr Val Lys Ala Arg Ser Arg Asp
                 110                 115                 120

 Ser Asp Glu Ser Gly Asp Lys Thr Thr Arg Ser Ser Ser Gln Tyr
                 125                 130                 135

 Ile Glu Ser Phe Trp Gln Ser Ser Gln Ser Gln Asn Phe Thr Ala
                 140                 145                 150

 His Asp Lys Gln Arg Ser Val Leu Ser Ser Gly Tyr Gln Lys Thr
                 155                 160                 165

 Pro Gln Glu Trp Ala Pro Gln Thr Ala Arg Ile Arg Thr Arg Met
                 170                 175                 180

 Gln Asn Asp Ser Ile Leu Lys Ser Glu Leu Gly Asn Gln Ser Pro
                 185                 190                 195

 Ser Thr Ser Ser Arg Gln Val Thr Gly Gln Pro Gln Asn Ala Ser
                 200                 205                 210

 Phe Val Lys Arg Asn Arg Trp Trp Leu Leu Pro Leu Ile Ala Ala
                 215                 220                 225

 Leu Ala Ser Gly Ser Phe Trp Phe Phe Ser Thr Pro Glu Val Glu
                 230                 235                 240

 Thr Thr Ala Val Gln Glu Phe Gln Asn Gln Met Asn Gln Leu Lys
                 245                 250                 255

 Asn Lys Tyr Gln Gly Gln Asp Glu Lys Leu Trp Lys Arg Ser Gln
                 260                 265                 270

 Thr Phe Leu Glu Lys His Leu Asn Ser Ser His Pro Arg Ser Gln
                 275                 280                 285

 Pro Ala Ile Leu Leu Leu Thr Ala Ala Arg Asp Ala Glu Glu Ala
                 290                 295                 300

 Leu Arg Cys Leu Ser Glu Gln Ile Ala Asp Ala Tyr Ser Ser Phe
                 305                 310                 315

 Arg Ser Val Arg Ala Ile Arg Ile Asp Gly Thr Asp Lys Ala Thr
                 320                 325                 330

 Gln Asp Ser Asp Thr Val Lys Leu Glu Val Asp Gln Glu Leu Ser
                 335                 340                 345

 Asn Gly Phe Lys Asn Gly Gln Asn Ala Ala Val Val His Arg Phe
                 350                 355                 360

 Glu Ser Phe Pro Ala Gly Ser Thr Leu Ile Phe Tyr Lys Tyr Cys
                 365                 370                 375

 Asp His Glu Asn Ala Ala Phe Lys Asp Val Ala Leu Val Leu Thr
                 380                 385                 390

 Val Leu Leu Glu Glu Glu Thr Leu Gly Thr Ser Leu Gly Leu Lys
                 395                 400                 405

 Glu Val Glu Glu Lys Val Arg Asp Phe Leu Lys Val Lys Phe Thr
                 410                 415                 420

 Asn Ser Asn Thr Pro Asn Ser Tyr Asn His Met Asp Pro Asp Lys
                 425                 430                 435

 Leu Asn Gly Leu Trp Ser Arg Ile Ser His Leu Val Leu Pro Val
                 440                 445                 450

 Gln Pro Glu Asn Ala Leu Lys Arg Gly Ile Cys Leu
                 455                 460

<210> 2577
<211> 3181
<212> DNA
<213> Homo sapien

<400> 2577
 ctcccttcca cagcactacc ccacctctgt gaataaaagc tttcccaact 50

 ttgtgatcac aattgaaaat gggtcactta ttattgagag aaaaccacca 100

 aaagtctcaa attcatcaca tcctctgacc catcttttaa tttttaaatg 150

 cagaagaaga aaccaaacgg aaccaaaaaa aaaagagaga gagagaataa 200

 atagaaaaga atgtggctgg gaattgtgaa tcagaagatt atacccccca 250

 attgtttttc aatccccttt tctcaaataa taaattagtt aaatcagttt 300

 ctgagttatg ccactggctg atgaagagtt gagaggtctc tttgcagaat 350

 gatctttttg tttcgttttg tttcttcttc tgcatttaaa aattaaaaga 400

 ttggtttgag gatgtgatga aattgagact ttttgtggtt ttctctcaat 450

 aataagtgaa ccaatttcaa atgtgatcac aaagtttgga aagcttttat 500

 tcacagaggt tgggtagtgt tgggagggga gtttaattac tcagattggc 550

 ctgttatttg atttcctcct ttgggaaaag aattatgtag ataccacatg 600

 gagacaggga aacaattgtg gtaaaactgt ggatcctgtt gctatttgcc 650

 cagtgagaaa acagattctg gtatttgatt tggtttttct ctttgtttcc 700

 agaatggatg aaagtccatg aacctcctaa gttataattt aaatttgttt 750

 ggggcaaggt gattttatag tcgagacaga gccctcggtc cttcctgccc 800

 catcactcac ttacgacatc acttccattg tgtgcatgtt tgttatagag 850

 gaggttttag gctacaatat ttgtttaacc tccctaagaa ctttcaaggc 900

 atctgtcctg aaagctgtta atttatggtc tagcagattt atattatatg 950

 cagataataa ttaactgggg ataaaagaat ggcaaggggt gacacaaagt 1000

 agcaaactga atacttctcc aatagcaacc ccaagctacc tcctcaccct 1050

 gcatcttgga gggaggcagg aaatttcttt tgaaataaag tgctggagct 1100

 gaattctgca ttacttatcg ttgctgctga aaccacctat aaaagacttg 1150

 ctggctaatg tgcattgtca tataatgtac actgtcacat ctttacagtc 1200

 ttgtatgtta tagaatacaa aataagttga tggttttgtt tggtgtgagc 1250

 tttttgtttg tttgtttagt tttgccttca taggttatat gccaagatag 1300

 tatttgataa gtcaatgaca tttggatgtt ttcttcaaag aattttattt 1350

 gacccagatt tcttataaag ttatcttaca ttaaggatgt cattttcatc 1400

 agaccttctt tctacatatt attcatgaag cataatgttg catttctcca 1450

 aattttatgc ctgaaagggt agtgttgctt cctaaggtat catgttgtct 1500

 ttgtgctttg tccatctctt ccgtggcgaa gctttatatc tgttcctaaa 1550

 acagttaatc ctgtgaaata aatattgaac ataatccaga agaatctctc 1600

 tgtttccctt ggggaatgcc atatttaatt caccagcagt aatcctttaa 1650

 taactggcag agcactttat tcttctggtg agctccctga atatttattt 1700

 ttctgattat aaattttcta tattagtagc attttttaat tattacttct 1750

 tcactataga gcatttactt ttagtctcta gatgtatatt ttggaatgct 1800

 atacttggca taacatagat taaaatcata atgcatgact aaaaactcct 1850

 tggatttatt tcccatttta aaatttttag cggtaagttc agatttataa 1900

 tctttctcta gacttccatg gtctgaatgt tgcctgctga agtagcaacc 1950

 taaaaagtat cccctgctta tgcttctcca gttggccctc catgtccata 2000

 ggcttcgcat ctgtgattca gcccactgtg ggtcaaaaat atttggggaa 2050

 aaaaatggat ggttgcgcct ttgctgaaca tgtacaaact tttttttgtc 2100

 attaaacaat atagtataac aactatttac aaagcattta cattgtatta 2150

 ggctattata ggtaatctag agatgattta aagtgtatgg taggatgtgc 2200

 ataggttata tgcaaatact acaccatttt tctataaggg acttgaacat 2250

 catggacttt agtatcctag ggggttcttg gaacccatca cccatagggg 2300

 caccatagga caactatagt accgtgttta tttcctatta attcaggttc 2350

 cgtttagagt ctaaaactaa aacctaatca tttagtcaca gtgtaaaaac 2400

 aaatggaaat aacagctcaa atcttcaaaa tattactata gcattatgtt 2450

 taaaataatc tacaacaaaa atgtaccatt ttcaagcagt actacattag 2500

 gagccctttt atagaaaata atttcttctt tacccccgtt ccagtgtgaa 2550

 tctagtattc tgttaacatt tgtgtggcat ttggagtttg tcatccccat 2600

 tgaagggaga gccttctcag acatgaagca agggaaacat actgaatagt 2650

 tttacacaaa tttgatctgg cttccatttg tccccctcat ttcccaaatg 2700

 tttaaatgta ttggatttgg attctcaatg tataagttgc cttatctgtt 2750

 aatgtctatc ttctgtctct ttaattttgt atatctgctg ttttgctttt 2800

 ggatacattt tctaattaga agtcacatga taaatataat cagtatagta 2850

 ataataccat aatgtgcaca tactcaataa ataaatgact gcattgttgt 2900

 aaatgagctc tcctttttgt tgttgttggt tggcgagtgg tttccatcaa 2950

 gtcatcatgg gaaaataatc aagttccata ttcacaggtt aggataggat 3000

 gtaatgattc tcagaagaac ccttctagta tgatatttgc ttatcaaaat 3050

 gtctcagaaa caaaatattt gaaaatactg tcacatttat tgtatttctc 3100

 tctgttctta tgccgtgcat gtagaatgta cccaatgttt atgaattaat 3150

 agataaataa ggtctattgt cttttgaaaa t 3181

<210> 2578
<211> 75
<212> PRT
<213> Homo sapien

<400> 2578
 Ser Leu Pro Gln His Tyr Pro Thr Ser Val Asn Lys Ser Phe Pro
   1               5                  10                  15

 Asn Phe Val Ile Thr Ile Glu Asn Gly Ser Leu Ile Ile Glu Arg
                  20                  25                  30

 Lys Pro Pro Lys Val Ser Asn Ser Ser His Pro Leu Thr His Leu
                  35                  40                  45

 Leu Ile Phe Lys Cys Arg Arg Arg Asn Gln Thr Glu Pro Lys Lys
                  50                  55                  60

 Lys Glu Arg Glu Arg Ile Asn Arg Lys Glu Cys Gly Trp Glu Leu
                  65                  70                  75

<210> 2579
<211> 2376
<212> DNA
<213> Homo sapien

<400> 2579
 cgagggcagc gccggtcggg agcgcagcgc ggcgcagctc ggcgcgcacg 50

 gcgggagcgg cgcgcgagtg gtcgggcctg gcggctggac gggcgcccct 100

 cgctgccccg cgcgctcccc gccgcccccc atgagcgcag ccccgcgcgg 150

 cccgggtccg taggcggcgg ggcgcccccc atgctgctgc agcccgcgcc 200

 gtgcgccccg agcgcgggct tcccgcggcc cctggccgcc cccggcgcca 250

 tgcacggctc gcagaaggac accacgttca ccaagatctt cgtgggcggc 300

 ctgccgtacc acactaccga cgcctcgctc aggaagtact tcgagggctt 350

 cggcgacatc gaggaggccg tggtcatcac cgaccgccag acgggcaagt 400

 cccgcggcta cggcttcgtg accatggccg accgggcggc agctgagagg 450

 gcttgcaaag acccgaaccc catcatcgac ggccgcaagg ccaacgtgaa 500

 cctggcatat ctgggcgcca agccgcggag cctccagacg ggctttgcca 550

 ttggggtgca gcagctgcac cccaccttga tccagcggac ttacgggctg 600

 accccgcact acatctaccc accagccatc gtgcagccca gcgtggtgat 650

 cccagccgcc cctgtcccgt cgctgtcctc gccctacatt gagtacacgc 700

 cggccagccc ggcctacgcc cagtacccac cggccaccta tgaccagtac 750

 ccatacgccg cctcgcctgc cacggctgcc agcttcgtgg gctacagcta 800

 ccctgccgcc gtgccccagg ccctctcagc cgcagcaccc gcgggcacca 850

 ctttcgtgca gtaccaggcg ccgcagctgc agcctgacag gatgcagtga 900

 ggggcgttcc tgccccgagg actgtggcat tgtcaccttc acagcagaca 950

 gagctgccag gccatgatgg gctggcgaca gcccggctga gctttagtga 1000

 ggtgccacca gcacccgtgc ctccgaagac cgctcgggca ttccgcctgc 1050

 gccctgggac agcggagaga tggcttctct ttaatctagg tcccattgtg 1100

 tcttgaggga ggactttaag aatgactgag aactatttaa agacgcaatc 1150

 ccaggttcct tgcacaccat ggcagcctct tcttgcacct tctcctgcct 1200

 ctccacactc caggttccct caggcttgtg tccccactgc tgcatcgtgg 1250

 cggggtgtca cagaccctct gcagcccctg gctgccctgg actgtgcaga 1300

 gatgcctgac tccagggaaa cctgaaagca agaagttaat ggactgttta 1350

 ttgtaacttg atcctcccga gctgtgagcg cagtctgagg tgtgaggaca 1400

 cggcctcctg ttggagtccc attttctcca tcagggcacg tgggcggctt 1450

 cctcaagccc ggaggagctc ccaggcgcac aggggccgcc ggtaacaggg 1500

 gccgccggcc aaaggcccct ttccagtcat agcactgaag ttgcaacttt 1550

 tttcttgtaa ttgttttgct actaagataa tttcagaagt tcagtctatt 1600

 ttttcagcgg atactgccgc caccaagaat ccaaaaccta tttttgactt 1650

 ggagagactt gcttttgttg gttccgcccg tggagacgac gacagtgttt 1700

 ctgtataata aagtgtctgc cggctcgcgg gccaggatcc tctcggtggg 1750

 atgggcacca cagacaggag gcccctcagg cccgtgcggg ccactgtctg 1800

 ctgccgcctg ccggggtggc agagtgagtt gtctcaggac cccgtcactg 1850

 cgacgttgac actctctcct tccttccttc cccaactccc caaacactgt 1900

 ggaagggaag aaggaagtga tccacagcat tcaggccact tggggtctag 1950

 accatggtgg tgccagcctg gggggggcag tggccctcag ctctgcccgc 2000

 tggagcggtt gagtgcagaa gggtgcgcct cttccctcta cccccgcacc 2050

 acctgctgtg tgccagcctg agacggttcc tgcctgtctt gggggttggt 2100

 ggagggtgga ggcagttctg ccagccgtgg cagggctgct atggggcatc 2150

 cagggctgtg ggggtctgga ggaggggaca tgaggtgaga ggtatcctgg 2200

 ccgagggcgg ggggcagcgg ggggtctccc tccggaccta cctcagggag 2250

 ctgagcgtgc aggcgctcca gggcaggcct gggacagagt caaggctcag 2300

 agaataaagg tagctaatct catcataata tttttattag aatgttctga 2350

 tgataaaaat aaaacttgtt ttcttt 2376

<210> 2580
<211> 216
<212> PRT
<213> Homo sapien

<400> 2580
 Met His Gly Ser Gln Lys Asp Thr Thr Phe Thr Lys Ile Phe Val
   1               5                  10                  15

 Gly Gly Leu Pro Tyr His Thr Thr Asp Ala Ser Leu Arg Lys Tyr
                  20                  25                  30

 Phe Glu Gly Phe Gly Asp Ile Glu Glu Ala Val Val Ile Thr Asp
                  35                  40                  45

 Arg Gln Thr Gly Lys Ser Arg Gly Tyr Gly Phe Val Thr Met Ala
                  50                  55                  60

 Asp Arg Ala Ala Ala Glu Arg Ala Cys Lys Asp Pro Asn Pro Ile
                  65                  70                  75

 Ile Asp Gly Arg Lys Ala Asn Val Asn Leu Ala Tyr Leu Gly Ala
                  80                  85                  90

 Lys Pro Arg Ser Leu Gln Thr Gly Phe Ala Ile Gly Val Gln Gln
                  95                 100                 105

 Leu His Pro Thr Leu Ile Gln Arg Thr Tyr Gly Leu Thr Pro His
                 110                 115                 120

 Tyr Ile Tyr Pro Pro Ala Ile Val Gln Pro Ser Val Val Ile Pro
                 125                 130                 135

 Ala Ala Pro Val Pro Ser Leu Ser Ser Pro Tyr Ile Glu Tyr Thr
                 140                 145                 150

 Pro Ala Ser Pro Ala Tyr Ala Gln Tyr Pro Pro Ala Thr Tyr Asp
                 155                 160                 165

 Gln Tyr Pro Tyr Ala Ala Ser Pro Ala Thr Ala Ala Ser Phe Val
                 170                 175                 180

 Gly Tyr Ser Tyr Pro Ala Ala Val Pro Gln Ala Leu Ser Ala Ala
                 185                 190                 195

 Ala Pro Ala Gly Thr Thr Phe Val Gln Tyr Gln Ala Pro Gln Leu
                 200                 205                 210

 Gln Pro Asp Arg Met Gln
                 215

<210> 2581
<211> 1524
<212> DNA
<213> Homo sapien

<400> 2581
 agcgggctgg gtgcgtgcgc ggcgactgcg acgggcagtg gcagtcatgg 50

 cggctcagtg cgtgaggttg gcgcggcgca gtcttcctgc tttggcgttg 100

 tctctcaggc catctccccg gttgttgtgc acagccacga aacaaaagaa 150

 cagtggccag aacctggaag aggacatggg tcagagtgaa cagaaggcag 200

 atcctcctgc tacagagaag accctcctgg aagagaaggt caagttggag 250

 gaacagctga aggagactgt ggaaaaatat aaacgagctt tggcagacac 300

 tgagaactta cggcagagga gccagaaatt ggtggaggag gcaaaattat 350

 acggcattca agccttctgc aaggacttgt tggaggtggc agacgttctg 400

 gagaaggcaa cacagtgtgt tccaaaagaa gaaattaaag acgataaccc 450

 tcacctgaag aacctctatg aggggctggt catgactgaa gtccagatcc 500

 agaaggtgtt cacaaagcat ggcttgctca agttgaaccc tgtcggagcc 550

 aagttcgacc cttatgaaca tgaggccttg ttccacacac cggttgaggg 600

 gaaggagcca ggcacagtgg ccctagttag caaagtgggg tacaagctgc 650

 atgggcgcac tctgagaccc gccctggtgg gggtggtgaa ggaagcttag 700

 ctgctgttga tggggtgggt gtttttaaac tcacttgatg taactctcaa 750

 ggctggttca ttgtttctca tctatgagta cgtgtgacct tttcccaaac 800

 cttattggaa accttaagta accagtggct aaacagaaaa gccggttgcc 850

 caactgcatt aatgaactct aattcgggag tctgttccct tttagtgcca 900

 cgcgttgaat agttccacat actttcagaa gagctcagca gggccctgcc 950

 tggtctcccg agcatcatga gtaacgtgtc tgctcagact ctgctgacac 1000

 caaagtattt taaacaaata aaaggtcttg gggaattctg tttggctacc 1050

 tgggcacgcc agtctgcacc atgtgtccct gcggcgcatg agtgactggc 1100

 gtatttagcc cgtcacattt cattcgctga aggaaaggca agagagttga 1150

 aacatttttc ttacttaaaa aaaatgatct ttgtgaagaa catagtgagt 1200

 tcgtttgtct tcagtcaaca gcggctgaaa ctgaccactg agaaatgggt 1250

 gtgggcactg acagttctcc cccattattt ggccaggaat tgagcttggc 1300

 ttggcaaagt tccttttacc ctgttctgtt catctaaatg cagacatatt 1350

 taaatcatat tcaactagtt actaatgacc tcaagttgta ttccctggca 1400

 aaatggactt tctcaaaata ggactgcacg cttggtgtac tttaaatgtt 1450

 aatgtttaat ttaaaatttt tatttaagag gattaaagcc ctaatgttta 1500

 ttttcctaca aaaaaaaaaa aaaa 1524

<210> 2582
<211> 217
<212> PRT
<213> Homo sapien

<400> 2582
 Met Ala Ala Gln Cys Val Arg Leu Ala Arg Arg Ser Leu Pro Ala
   1               5                  10                  15

 Leu Ala Leu Ser Leu Arg Pro Ser Pro Arg Leu Leu Cys Thr Ala
                  20                  25                  30

 Thr Lys Gln Lys Asn Ser Gly Gln Asn Leu Glu Glu Asp Met Gly
                  35                  40                  45

 Gln Ser Glu Gln Lys Ala Asp Pro Pro Ala Thr Glu Lys Thr Leu
                  50                  55                  60

 Leu Glu Glu Lys Val Lys Leu Glu Glu Gln Leu Lys Glu Thr Val
                  65                  70                  75

 Glu Lys Tyr Lys Arg Ala Leu Ala Asp Thr Glu Asn Leu Arg Gln
                  80                  85                  90

 Arg Ser Gln Lys Leu Val Glu Glu Ala Lys Leu Tyr Gly Ile Gln
                  95                 100                 105

 Ala Phe Cys Lys Asp Leu Leu Glu Val Ala Asp Val Leu Glu Lys
                 110                 115                 120

 Ala Thr Gln Cys Val Pro Lys Glu Glu Ile Lys Asp Asp Asn Pro
                 125                 130                 135

 His Leu Lys Asn Leu Tyr Glu Gly Leu Val Met Thr Glu Val Gln
                 140                 145                 150

 Ile Gln Lys Val Phe Thr Lys His Gly Leu Leu Lys Leu Asn Pro
                 155                 160                 165

 Val Gly Ala Lys Phe Asp Pro Tyr Glu His Glu Ala Leu Phe His
                 170                 175                 180

 Thr Pro Val Glu Gly Lys Glu Pro Gly Thr Val Ala Leu Val Ser
                 185                 190                 195

 Lys Val Gly Tyr Lys Leu His Gly Arg Thr Leu Arg Pro Ala Leu
                 200                 205                 210

 Val Gly Val Val Lys Glu Ala
                 215

<210> 2583
<211> 6815
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1846-1877
<223> Unknown base

<400> 2583
 tcggctcgcg gctttctgat tatgcagaac ttaaatctat gcctcagtga 50

 cccatacagc attccagttc ctatcaccta ctgtcttgtc cctatacttg 100

 cagcagttgt ccagggttat tctttgtctg tattagaatt ttttttcagg 150

 ttgcttaagg aatcttgcag atacttgtga caaagaatca taaatgctgt 200

 tgttaaactg aataatgaat tgagtcccaa atgttcgtgc taattaatgc 250

 tttttgagtt ggagatgaaa tgagagtaat atcatcaagc tgtggattaa 300

 agttatcctc aaagccccat catctacaaa aagaatagga caggaactgc 350

 ctttgtgcag gtgcaagacc atgttacttt tgagcagtga gcttgagatg 400

 tctgggatac aaattgggtt ccctattaac tactaatcat tccttttttt 450

 tctttcacct tcagccactc acaactgacc ttcactacta ttacatcctg 500

 gagctgtcgt tttattggtc tttgatgttt tctcagttca ctgatatcaa 550

 aagaaaggac tttggcatta tgttcctgca ccaccttgta tctattttct 600

 tgattacctt ttcatatgtc aacaatatgg cccgagtagg aacgctggtc 650

 ctttgtcttc atgattcagc tgatgctctt ctggaggctg ccaaaatggc 700

 aaattatgcc aagtttcaga aaatgtgtga tctcctgttt gttatgtttg 750

 ccgtggtttt tatcaccaca cgactgggta tatttcctct ctgggtgtta 800

 aataccacat tatttgaaag ctgggagatc gttggacctt acccttcctg 850

 gtgggttttt aacctactgc tattgctagt acaagggttg aactgcttct 900

 ggtcttactt gattgtgaaa atagcttgca aagctgtttc aagaggcaag 950

 gctgggaagt ggaaccctta catgtgtcca aggatgatcg aagtgatatt 1000

 gagtctagct cagatgagga ggactcagaa cctccgggaa agaatcccca 1050

 cactgcgaca accaccaatg ggaccagtgg taccaacggg tatctcctga 1100

 ctggctcctg ctccatggat gattaattac tcaaaactac aagtcccaag 1150

 caaagtgaac tatttgttcc tggaagtatt taataagttg caaatgcagt 1200

 tcctttcata atatctcagc accagaaaca aaaattaaga ttatcaaagc 1250

 attttgaata gtgcactgcc atgtgtcctg tctgtgaatg aagaagaatt 1300

 accattctct ctttgtaggc atgctgtatg taattgacac aagggaacag 1350

 tatttgcatt tgtactgtct tagaatatta tttatttttt tgtatttgta 1400

 aatctgtgga caaaagaggg tttcctcact ccttttactc actgggctca 1450

 tgacagtgaa ggagatgctc catctgcttc tccccctttc tcttgctgta 1500

 gtccaatgtg ctatgagcat cagcttactt tgtcacttag agcaagcaaa 1550

 acccagtgca agagtctcgt tcagctctaa ataggtttgc tttcttttag 1600

 ttacagtgcc cattttgaaa ttgcctatac agtcttagtg accatttaaa 1650

 ccggacgaac taggtgttta attttcactc ttcatgttca attagcagtt 1700

 caaattaaag aagatggtta ttggagaact tttttgaatg gttttgtatt 1750

 aaattgcttt gaaatagatt tcatttcttg tgcacacagc caagatttct 1800

 tcaatgggtg tgagctagtt gagggttaac cttgtaggtt gcagannnnn 1850

 nnnnnnnnnn nnnnnnnnnn nnnnnnngat gaggtcagtg ctctgatttt 1900

 gaaggaggat attcactgaa gctcatagtt ataaacaagg aaatcactgt 1950

 taagaatggg aatttgtcct gtgttctggg aataacataa agagagcaac 2000

 tgatttcagc caggttttgc cactacccta taattagtgc agtcttatgt 2050

 tataaaagaa agaagttaac tatatttggg gacaaaaaaa tatttcaaga 2100

 gttgataaag attacctgtg cagtgcagag cactttaatg caaccagctt 2150

 tcaagaaaaa gccctatcta gtacttgatg ttgatgtttt tattttgctg 2200

 agcaaaataa agccaatggg agaaagacta ttttaccctt tgcttttctc 2250

 cttaaacgta atccagatga ctttcctgtt actaaacact gagcagcatt 2300

 acactacaat gcttctttgg tttccaggaa tttttttcaa atggggctgt 2350

 ttctggaaaa atgaaaaatt ctattggaca atggcaatat caacaatgag 2400

 gaaaattact gaagaataag tttccataag tctcctacat agcagtgtta 2450

 tttatgtaca gataagaaaa ccatatgtca gccaaagatt ttatctcttc 2500

 ttctaacttt tagtaagagg aaaaagggat tataaaaccc ttcataaatc 2550

 aagaaggcca tcacttagaa cgaaccccaa acaaaaatgc cataatataa 2600

 atgtgtgaat cagggctgtg aagacaacag cagaaatgct aacaagcgtg 2650

 cagaaacacc agagagtgcg tatcctgctc agaaccattc acatttaatt 2700

 caattcttgg aaaaaattaa agctttttgc ccacaatttg caatctgtgg 2750

 gttaatagtt aaaagaatgt tcccaaccaa aaaattctta ccgtaatatt 2800

 atatcttgcc ctacttattt acaaaataat atgtttctgt tatggtcctt 2850

 agtaataatt gaagaggctt agaaatacat ctgcttgttt attgagaaaa 2900

 cgatgcaaat aattctgctt ttagagcctt gttattttat ttcacaaaac 2950

 aggcatatgt ctaggagtgt aatttgtgga tggttgagtt tgtaagaaca 3000

 atcataaaag gacttgttag tctccagaac atctgctaaa atgcaagtat 3050

 atgtataagg taatagcata ttacagctga aaattttgag aaggtaaaag 3100

 tttcttaatt aaaatatgaa catatttagc ttgctttagt gtctggggca 3150

 agtcctctca atggctaaaa ttaactttag agatccatgt gttcaggttt 3200

 agatcatatg acactcgagc acagaagaat aatttcaagg aggtcatctt 3250

 gtaaattaaa ggtttagaag aattgcataa aacgtagtaa atggggtctg 3300

 tcattagcaa aggcaaatct aagcaatcat ttttcccccc agaagttact 3350

 tagaaggaga actgggaaca cttggggtct ctctaactga tggcattcac 3400

 ttcacacagt cgtctatgtt atccagagat ttttatttca ttttacattt 3450

 tagggcacag ttctttgggg ctaattaaaa tggggtttgc aggcttttta 3500

 tggtgaagaa taatatatct ctgtctatag ctttcccatg gtagcctgat 3550

 aaggctgaga gagaaaaata tgtgcagtat ctcatcctcc ccctgtacca 3600

 ggccatagct ttgaagtgta ttttgtaaat tcaactatag gttagtcaga 3650

 atgctgtttt tcgttaatta acttagcctg tgttgatatc tcctccttcc 3700

 tggtcacatt caaaccttcc cagagtacaa aggggtatgt agaaaggatt 3750

 ccagaagaag taatacttta ttctctaatg ttaatagctt ttctggatct 3800

 cttagtaggg ggaaagtaga aaatcgagta gaatttggcc tcaggtcaat 3850

 aaatgatata aaaacatgtg ttctatttat gtatatatat gtatgtttct 3900

 ccaaaaagtg ataaaaccaa aatatcactg actcatccct acccatattc 3950

 ttttcataaa acccactcac caggtacaat agaaacttcc ctccttgttt 4000

 gtcagcctcc tgttcatgtt ccccacacac ctgaaggtgg tagaatcttt 4050

 tcagcctctt agccagtgag ctaaatatgg ctaagcacag gtcataagag 4100

 cacctaaggc cagcatataa gccaactaca gttcaccttt ccaaatttgg 4150

 tcctatggat gttgagcata gggaagcaac tctcagtatt ttggattatt 4200

 caagtgtatg tggtaaaaat gcagatgatt gctgctttac cccagggttt 4250

 attagcatcc tacttctgct gggctgcatc attatataat gccacaggca 4300

 tctagtcaag gtaaagaagc cagaaaggtt aggcaagaag tgagataaaa 4350

 tcagatcacc tttgatcaaa atggttggtg aacctccaca tgtccagttc 4400

 tgttgccaaa ctttccattc agagtatttg gtggagtttg aatttgagca 4450

 aactaaatgc cttcatctta ggtagaaagg gcctgaatct tccattttat 4500

 attcaaacct cattgttatt tggcctaagt aaaaagtcag atttcatttc 4550

 catttacctg agttcgcttt aaagagcttt tcaaagagag ctttatagac 4600

 acccacaatt gtccccaatc tcttcatgat gttgcattaa tagttgtttt 4650

 tgtccctttc ttggaaatgt taatgccaaa gttgcctgaa cattgggcgg 4700

 ttttcttaat ttgaagtata aaaattataa agagtaattc caaaggtatt 4750

 aaaagattgt ttaacagtat gtgtggtgat gtcattatct ccagagaggc 4800

 ttcaagaaat cctttggaaa taaaaagtta aatgtttaca tttcatgtgg 4850

 tatttcaggt cttcaggttc tgattagctt acttttttcc tttgtctttg 4900

 gctgatttct gctttgtaga taaataataa tagccctgag atgtttctaa 4950

 catttaaata agaaaaaaat caaatcgaag tcagcctgct ggaaaagtga 5000

 tcacatggca gttgcagtaa cttgtatgga aagagaaaat gcaatgagcc 5050

 cagttactgc acttgccact accatgctgt ccatggaagg aataatcagc 5100

 agttcagttg tcacaagccg cccttgaaga aaacgcagca aaatatttta 5150

 aaatgaagat attgcagtcc ccagagccag tgaaggtttc ttttggtaaa 5200

 atgaaattgt gccattgtca aagtaccccg tagtgatgag cactgactgg 5250

 ttcactggcc acattttagt tcttcataat aataggccac aaaagggctc 5300

 tgtggtttgc ctccatgtgc actggcccct ccccacccct agggggcact 5350

 cagtagctgc tgagaaggcc tgtccacgag gctgttggaa cccctccaat 5400

 aaatacttag aggtagtgta tctgatgctt gttttcgtgg agaaaattgt 5450

 attggagaac ttaaaacatc acgaatattt ttaataggat ccgcagacac 5500

 ccaaaggaga agcttggtct tttccaggta tttccaactt gagttcaacc 5550

 caaagccttt gaaaggaatg cattaccaca tgaccacatg ctgagacccc 5600

 atggggtcta acacgggacc taagaaagtc tctgcagcca gatagtacat 5650

 ggtgtctcca caaaactagg cattctggag attgcccaga aagggatgtg 5700

 aggggaccgt taagatctgt cttgcttatc tcatgcactc acattccttc 5750

 agcctcctgg agttcctgat aaaaggaagc cagggtgttg acatttttta 5800

 gctattgatt tcccaatagc ttgtggatca gttgtacacc cacacttcct 5850

 tctctgccta attccgtttt tctggaaaaa gtagtatgcc catgtatgtg 5900

 tgtttttctt aacacaggtc catgaaagtt tggcttcctg gtttgatgtc 5950

 tgttgcgtgg cctggaaacc agggagcagc aactattgag atggtttctg 6000

 tgttcagtga aaaattctat ttcattgaga caattttttc tttatccaca 6050

 gtaatttttt gacactgtca tcatgaaact acccttagga aaataagatt 6100

 acctgcaaaa aaaaaaaaga aatgagttat ggaataggaa cagttatgtg 6150

 atgattctga aactttaact tagagcttca ttactttaag aatggaaaac 6200

 aacctctgag tttgatttcc caaagtttca taaagcccct aagctcatga 6250

 ttttcatcaa ctctttgccc acatagtcat ttacctccac agccgtttgt 6300

 tgtcatagaa ggggtggtgg tgtttggatt tgattttttt caacttgcag 6350

 tgagaaatag gataggtgac aaaaccttac ttgttttctt aagacaattc 6400

 agtgcttgag catctctgtc agaaatggaa tgaaatactg ttagccaatt 6450

 agaattattt tatgtattgt tattgtgttt tgctgatttt tatatgaaaa 6500

 tataattatt cattcttgat ctctggaagc aatcattatt atgaggatca 6550

 ttttactttg gaaacacttt cataataaag ataagtatta agagtgcagt 6600

 gtaagtgccc tttactgtaa atgctaacca gctcgtgtgg gtaaaacatc 6650

 acatctcacc tgatgaggtt aataaaggct cacatcatcc cagtagattg 6700

 ttacaagcct cgtcaactcc cagtatcatt gtgatcattg agaaagtaat 6750

 gttacgttaa cttggataga ctgtagtatc tctttgaaaa ttaagattaa 6800

 aacctcaatg ctaaa 6815

<210> 2584
<211> 191
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1846-1877
<223> Unknown amino acid

<400> 2584
 Met Phe Ser Gln Phe Thr Asp Ile Lys Arg Lys Asp Phe Gly Ile
   1               5                  10                  15

 Met Phe Leu His His Leu Val Ser Ile Phe Leu Ile Thr Phe Ser
                  20                  25                  30

 Tyr Val Asn Asn Met Ala Arg Val Gly Thr Leu Val Leu Cys Leu
                  35                  40                  45

 His Asp Ser Ala Asp Ala Leu Leu Glu Ala Ala Lys Met Ala Asn
                  50                  55                  60

 Tyr Ala Lys Phe Gln Lys Met Cys Asp Leu Leu Phe Val Met Phe
                  65                  70                  75

 Ala Val Val Phe Ile Thr Thr Arg Leu Gly Ile Phe Pro Leu Trp
                  80                  85                  90

 Val Leu Asn Thr Thr Leu Phe Glu Ser Trp Glu Ile Val Gly Pro
                  95                 100                 105

 Tyr Pro Ser Trp Trp Val Phe Asn Leu Leu Leu Leu Leu Val Gln
                 110                 115                 120

 Gly Leu Asn Cys Phe Trp Ser Tyr Leu Ile Val Lys Ile Ala Cys
                 125                 130                 135

 Lys Ala Val Ser Arg Gly Lys Ala Gly Lys Trp Asn Pro Tyr Met
                 140                 145                 150

 Cys Pro Arg Met Ile Glu Val Ile Leu Ser Leu Ala Gln Met Arg
                 155                 160                 165

 Arg Thr Gln Asn Leu Arg Glu Arg Ile Pro Thr Leu Arg Gln Pro
                 170                 175                 180

 Pro Met Gly Pro Val Val Pro Thr Gly Ile Ser
                 185                 190

<210> 2585
<211> 1488
<212> DNA
<213> Homo sapien

<400> 2585
 tttatacttg gggaaaaaac aaggccatat gtaaaaaccc ttccaatgcc 50

 taagtgtctt tctcctgcaa ctccaaaccc agactcgcca ctttgggtgc 100

 acaggtggtt aggtcagcca actggttctg cctgtcgcct tgccacggag 150

 gaggcttcta attagctgga aaagagtatt tttctaatac gttgcaagga 200

 ttagccaaat cttcttattg aagaaagaag aaaagtgaag agtggttacc 250

 tatacctagc atagtacaat cagaacctcg tggagaccac cggggacagg 300

 cttgcggacg ccggctgttc ttcccgccac gatctttctg tggtagcggc 350

 cagcagaaga cacggcctgc tccccactcc ctttccccac tccttcttta 400

 ttgcacacag gacaccagtc ttcaaggaaa gggacttttt tccagtctgc 450

 caatcatatt gggaaagtgc tagctgtgct caccttcatg gggctgtttc 500

 cagctcgtcc acaagctcat cgattttctt tagtagatta ccggtgtaaa 550

 tacccagtgt gcttatgagt cagttagtag acgtcttcat tcattggagt 600

 aactggttta ggctttccag tttggaaaag gagcagagag ctgtccatct 650

 ggattgatgg aagaaaagag aacctcatcc atgcctggag aacatctaga 700

 aaaccttcag ccagcctcca gtgctgtcga gagaccacct tcccccgacc 750

 cggaggcact tccttggggt ctttctctag ggtctcttct ctacaaagca 800

 caacactaat gttcgtttcc ttagacctca gttcaagtgc ccctatttat 850

 ttcaataaga acgcacatat cccagctgtt ttttgtttgt cacctctatt 900

 tagttgttac ctgtttctct cttctttcac cccttgtcct tttccaccct 950

 tttaagagtt acgctagcag atcttactcc acgtatactt tttggtttgt 1000

 gaaggcatcg gttaagggca caaagacagc catggggaca tttatgtaaa 1050

 tacgtctcta attgccacac tgcagctgaa cagtgtgtag tattttccca 1100

 gtcagctttg ccatactgac gtcaatcatt tgagagaaat tattcagatt 1150

 ttatttttgt atctgtggta acaaaacatt aaccaaaaga ttttctgtcc 1200

 agaagcctcc ccgacccccc aagctatttg ctcacattaa caaattaaag 1250

 tgcctgaagc ataattcatt ctttacctgt atactaaaaa ccctgttgta 1300

 ttgatttttt tataataagc ctttttacct ctgtgtaaaa aatatatata 1350

 caagtgtatg atgtacattt tagttcttaa ctttttttta tggtttctaa 1400

 tatgtatgac caatgtagcc attgctttaa aatgtaccgt gtaaatataa 1450

 acacatccta tcagaaaaaa aaaaaaaaaa aaaaaaaa 1488

<210> 2586
<211> 54
<212> PRT
<213> Homo sapien

<400> 2586
 Phe Ile Leu Gly Glu Lys Thr Arg Pro Tyr Val Lys Thr Leu Pro
   1               5                  10                  15

 Met Pro Lys Cys Leu Ser Pro Ala Thr Pro Asn Pro Asp Ser Pro
                  20                  25                  30

 Leu Trp Val His Arg Trp Leu Gly Gln Pro Thr Gly Ser Ala Cys
                  35                  40                  45

 Arg Leu Ala Thr Glu Glu Ala Ser Asn
                  50

<210> 2587
<211> 2199
<212> DNA
<213> Homo sapien

<400> 2587
 gggggtattt cctgaaagat gctaatctat ttgccaaact tggtcttgaa 50

 tgtactgggg gcttcaaggt atgggtatat ttttcttgtg tccttgcagt 100

 tagcccccat gtcttatgtg tgtcctgaaa aaataagagc ctgcccaaga 150

 ctttgggcct cttgacagaa ttaaccactt ttatacatct gagttctctt 200

 ggtaagttct ttagcagtgt tcaaagtcta ctagctcgca ttagtttctg 250

 ttgctgccaa cagatctgaa ctaatgctaa cagatccccc tgagggattc 300

 ttgatgggct gagcagctgg ctggagctag tactgactga cattcattgt 350

 gatgagggca gctttctggt acaggattct aagctctatg ttttctatac 400

 attttcatct gtacttgcac ctcactttac acaagaggaa actatgcaaa 450

 gttagctgga tcgctcaagg tcacttaggt gagttggcaa gtccatgctt 500

 cccactcagc tcctcaggtc agcaagtcta cttctctgcc tattttgtat 550

 actctcttta atatgtgcct agctttggaa agtctagaat gggtccctgg 600

 tgccttttta ctttgaagaa atcagtttct gcctcttttt ggaaaagaaa 650

 acaaagtgca attgtttttt actggaaagt tacccaatag catgaggtga 700

 acaggacgta gttaggcctt cctgtaaaca gaaaatcata tcaaaacact 750

 atcttcccat ctgtttctca atgcctgcta cttcttgtag atatttcatt 800

 tcaggagagc agcagttaaa cccgtggatt ttgtagttag gaacctgggt 850

 tcaaaccctc ttccactaat tggctatgtc tctggacaag tttttttttt 900

 tttttttttt taaacccttt ctgaactttc actttctatg tctacctcaa 950

 agaattgttg tgaggcttga gataatgcat ttgtaaaggg tctgccagat 1000

 aggaagatgc tagttatgga tttacaaggt tgttaaggct gtaagagtct 1050

 aaaacctaca gtgaatcaca atgcatttac ccccactgac ttggacataa 1100

 gtgaaaacta gccagaagtc tctttttcaa attacttaca ggttattcaa 1150

 tataaaattt ttgtaatgga taatcttatt tatctaaact aaagcttcct 1200

 gtttatacac actcctgtta ttctgggata agataaatga ccacagcacc 1250

 ttaatttcta ggtgggtgcc tgtgatggtt cattgtaggt aaggacattt 1300

 tctctttttc agcagctgtg taggtccaga gcctctggga gaggaggggg 1350

 gtagcatgca cccagcaggg gactgaactg ggaaactcaa ggttcttttt 1400

 actgtggggt agtgagctgc ctttctgtga tcggtttccc tagggatgtt 1450

 gctgttcccc tccttgctat tcgcagctac atacaacgtg gccaacccca 1500

 gtaggctgat cctatatatg atcagtgctg gtgctgactc tcaatagccc 1550

 cacccaagct ggctataggt ttacagatac attaattagg caacctaaaa 1600

 tattgatgct ggtgttggtg tgacataatg ctatggccag aactgaaact 1650

 tagagttata attcatgtat tagggttctc cagagggaca gaattagtag 1700

 gatatatgta tatatgaaag ggaggttatt agggagaact ggctcccaca 1750

 gttagaaggc gaagtcgcac aataggccgt ctgcaagctg ggttagagag 1800

 aagccagtag tggctcagcc tgagttcaaa aacctcaaaa ctggggaagc 1850

 tgacagtgca gccagccttc agtctgtggc caaaggccca agagcccctg 1900

 gcaaccaacc cactggtgca agtcctagat tccaaaggct gaagatcctg 1950

 gagtctgatg tccaagagca ggaagagtgg aagaaagcca gaagactcag 2000

 caaacaaggt agacagagtc taccaccaca gtggccatac caaagaggct 2050

 accgattcct tcctgctacc tggatccctg aagttgccct ggtctctgca 2100

 ccttctaaac ctagttctta agagctttcc attacatgag ctgtctcaaa 2150

 gccctccaat aaattctcag tgtaagcttc aaaaaaaaaa aaaaaaaaa 2199

<210> 2588
<211> 33
<212> PRT
<213> Homo sapien

<400> 2588
 Met Leu Leu Phe Pro Ser Leu Leu Phe Ala Ala Thr Tyr Asn Val
   1               5                  10                  15

 Ala Asn Pro Ser Arg Leu Ile Leu Tyr Met Ile Ser Ala Gly Ala
                  20                  25                  30

 Asp Ser Gln


<210> 2589
<211> 1704
<212> DNA
<213> Homo sapien

<400> 2589
 agagtcgctg tttgcttagg agagatgaac ctttctggtg ggcagcaccg 50

 acacccaggg ggtggacccc cgaggatgaa tgcctctagg cctccgcaac 100

 atattcaaga atgaatggga gacgctagag taaaatgggg gcagagagga 150

 tatcagggag caagatgcaa actgtgtgca tccactctcg taaacaagta 200

 gctggtcaca accagaaagg ttcatctctc ctaagcaaac agcgactctt 250

 tcagaggaag tttccctctt tcaatcgtgg ccttattttc aactccggtg 300

 ccttctcgtg atgttaatca tttccttttt tccccacact aagctctctt 350

 ttctatcttt ctctctcttt ccaatcttac gccatggcca tcagttcatt 400

 tcagccttcc agtgctacac ccacttcttg gctgacacac ttctgctcta 450

 aggtgactgg ttttcttgcc aattttcaaa gagtggtact aacccccaac 500

 ccgctttccg caccccgtcc tctccgccag cagtactggt tgcactaact 550

 gtgagtgtct tgcatactga tggactcatt tggtggcatg gttggctaac 600

 agcatggcgg ggggtgttca gcttgagacc catgcctgtg ttcatttccc 650

 atggagctgg cagcctggtc taccccaagt gcatgccccg cctctcctct 700

 ctcccttggg tctgcctgcg tgcatgcttc tccagttgcg tctgcgaagc 750

 tacctacttt cttgggaggg tcgaccttga tcatgaaaca ataccatgag 800

 ggggcctctg tcacctttga aaagaacact ttttgagcag cctcaaaaag 850

 ctcatacata ccagcgcctt cttaaattgg ctctaatgta aagattgtta 900

 atgtcattta tcaaaaccat aggtgattat ttggagggat ttaaaaaact 950

 taattactct caggcctcat cccaagcttg acacatgctc tgtaggttga 1000

 acacataatc acaaatattc tagcaaatgc tgccttggtt gcagcctgca 1050

 ctgtagaccc aagggttttg ctgtggctct tcttatctcc cttggctcat 1100

 aaagccccag atgatgccag agcttcaatt agagccatca tcatcccagg 1150

 cagggatatc tttgagaaat gactcagttc agccccaggc ccctgtgact 1200

 ctgcttaaag cacacatttc tgctgactct tgtacctggg gcagcaggat 1250

 aatcaccaac acactcttaa cgagaaacaa cacaccaagc acagtggagc 1300

 tgtcctaggc aacactcgcg gtctcaggct gcggtgggcg tctgtcctgc 1350

 atgtggccca gaccaccctg acccccgggc ctgcctgcct ggccctgcat 1400

 gctgcacgct cactgtattt gtgcagatcc tggccagtac aaagtcgttg 1450

 ctcttgtctt atcttctctt acagagtctc cctcccttta tagaatgtca 1500

 accaaagagt gccctcctcc cctctcagcc tcctctttag ctagcctccc 1550

 catctcatca caacgcatgt ctgtgacctt tggtaatcat ttacagtgcc 1600

 acacggaacc ctgtattttg cacacagcaa aacaaacaat gtttagcttt 1650

 atttatggta tttgatgctg taaatggaaa taaatattgt tctttataaa 1700

 gctc 1704

<210> 2590
<211> 37
<212> PRT
<213> Homo sapien

<400> 2590
 Arg Val Ala Val Cys Leu Gly Glu Met Asn Leu Ser Gly Gly Gln
   1               5                  10                  15

 His Arg His Pro Gly Gly Gly Pro Pro Arg Met Asn Ala Ser Arg
                  20                  25                  30

 Pro Pro Gln His Ile Gln Glu
                  35

<210> 2591
<211> 3885
<212> DNA
<213> Homo sapien

<400> 2591
 ccgggccgcc tcgctcgctc ccagctctgt cagtggcccg cggggcccga 50

 tcgctgcgcc cgcggccagg gccgaggcag gcctgacccg gggccgggca 100

 gcccgcgcga ctttcggaac atggcaaccc gtgtgtgtct catcccagaa 150

 agagaagact ttaaccactg tgatgcctga gaatccagtg tgacgtttct 200

 ccagatactt catgctgttc acctgtgtcc tcgccgcacc actgccgcac 250

 acgactcctg aaccatgggg gaaaacgagg atgagaagca ggcccaggcg 300

 gggcaggttt ttgagaactt tgtccaggca tccacgtgca aaggtaccct 350

 ccaggccttc aacattctca cacgacacct ggacctagac cctctggacc 400

 acagaaactt ttattccaag ctcaagtcca aggtgaccac ctggaaagcc 450

 aaagccctgt ggtacaaatt ggataagcgt ggttcccaca aagagtataa 500

 gcgagggaag tcgtgcacga acaccaagtg tctcatagtt gggggaggac 550

 cctgtggctt gcgcactgcc attgaacttg cctacctggg agccaaagtg 600

 gtcgtggtgg agaagaggga ctccttctcc cggaacaacg tgctacacct 650

 ctggcctttc accatccatg accttcgggg cctgggagcc aagaagttct 700

 atgggaagtt ctgtgctggc tccatcgacc atatcagtat tcgccaacta 750

 cagctcatcc tattcaaggt ggccctgatg ctgggagttg aaatccatgt 800

 gaatgtggag ttcgtgaagg ttctagagcc tcctgaagat caagaaaatc 850

 aaaaaattgg ctggcgggca gaatttctcc ctacagacca ttctctgtcg 900

 gagtttgagt ttgacgtcat cattggtgcc gatggccgca ggaacaccct 950

 ggaagggttc agaagaaaag aattccgtgg gaagctggcg attgccatca 1000

 ccgccaactt cataaacaga aacagcacag cggaagccaa ggtggaagag 1050

 attagtggtg tggctttcat cttcaatcag aaattttttc aggaccttaa 1100

 agaagaaaca ggcatagatc ttgagaacat tgtttactac aaggactgca 1150

 cccactattt tgtaatgaca gccaagaagc agagcctgct cgacaaaggt 1200

 gtcatcatta acgactacat cgacacagag atgctgctgt gtgcggagaa 1250

 cgtgaaccaa gacaacctgc tatcctatgc ccgggaagct gcagactttg 1300

 ccaccaacta ccagctgcca tccttagact ttgccatgaa ccactatggg 1350

 cagcctgatg tggccatgtt tgactttacc tgcatgtatg cctcagagaa 1400

 cgcggccctg gtgcgggagc ggcaggcgca ccagctgctc gtggcccttg 1450

 tgggtgacag cttgcttgag ccattttggc ccatgggtac aggctgtgcc 1500

 cgtggcttcc tggcagcctt tgacacggca tggatggtga agagctggaa 1550

 ccagggcacc cctcccctgg agctgctggc tgaaagggaa agtctctacc 1600

 ggctgttacc tcagacaacc ccggagaaca tcaacaagaa ctttgagcag 1650

 tacacgttgg acccagggac acggtaccca aacctcaact cacactgtgt 1700

 caggccccat caggtgaagc atttgtatat cactaaggag ctggagcact 1750

 accctctcga gagactgggc tcggtgagga gatctgtcaa cctctccagg 1800

 aaggagtcag atatccggcc cagcaagctc ctgacctggt gccagcagca 1850

 gacagagggc taccagcatg tcaacgtcac cgacctgacc acatcctggc 1900

 gcagtgggtt ggccctgtgt gccatcatcc accgcttccg gcctgagctc 1950

 atcaactttg actctttgaa tgaagatgat gctgtggaga acaaccagct 2000

 cgcatttgat gtggccgagc gagagtttgg gatccctcca gtgaccacgg 2050

 gcaaagagat ggcatctgcc caggagcctg acaagctcag catggtcatg 2100

 tacctctcca agttctacga gctcttccgg ggcaccccac tgaggcccgt 2150

 ggattcttgg cgcaaaaact atggagaaaa tgctgacctc agcttggcca 2200

 aatcatccat ttctaataac tatctcaacc tcacatttcc aaggaagagg 2250

 actccacggg tggatggtca aaccggagag aatgacatga acaaacggag 2300

 acggaagggc ttcaccaacc tggacgagcc ttcaaacttt tccagccgta 2350

 gcttgggctc caatcaagag tgtgggagca gtaaggaagg tggaaatcag 2400

 aacaaagtca agtccatggc gaatcagctg ctggccaagt ttgaggagag 2450

 cactcggaac ccctcactca tgaagcagga acgccgtgtc tcagggatag 2500

 gtaagccggt cctgtgctct tcctccggcc ctcctgttca ctcttgctgc 2550

 cccaagccgg aggaggccac acccagccca tcacctcctc tgaaaaggca 2600

 gttcccctct gtggtcgtga cggggcacgt gctcagagag ctcaagcaag 2650

 tgtctgctgg cagtgagtgc ctgagcagac cttggagagc cagagccaag 2700

 tctgacctac agctgggtgg gacagaaaat ttcgctaccc tgccttctac 2750

 ccgcccgagg gcgcaggctc tttccggggt gctgtggcgg ctgcagcaag 2800

 tggaggaaaa gattctccag aagagggctc agaacttggc caacagggaa 2850

 tttcacacaa agaacattaa ggagaaggcg gctcaccttg cctccatgtt 2900

 tggacacggg gatttcccgc agaataaact gctctctaaa ggcctgtctc 2950

 atactcatcc tccatctcct ccctctcgcc ttccgtctcc tgatccagct 3000

 gcttcttcct ctccatcaac tgttgactct gcttctcctg ccagaaagga 3050

 aaagaagtca ccttcagggt tccattttca tcccagccat ttgagaacag 3100

 tgcatcctca gctgacggta gggaaagtgt ccagcggaat aggggctgca 3150

 gctgaagtcc tggtcaatct gtacatgaat gatcacagac ctaaggccca 3200

 ggccacctct ccagacctgg aatctatgcg aaagtcattt ccccttaacc 3250

 tgggaggcag cgacacgtgt tacttctgta agaaacgtgt gtacgtgatg 3300

 gaacggctga gcgccgaggg ccacttcttc caccgggagt gtttccgctg 3350

 cagcatctgt gccaccacct tgcgcctggc cgcctacacc tttgactgcg 3400

 atgaaggcaa attttactgc aagcctcact tcattcactg taaaaccaat 3450

 agcaaacaac ggaagagacg ggcagagttg aagcaacaaa gagaggagga 3500

 ggcaacatgg caagagcagg aagcccctcg gagagacact cccaccgaaa 3550

 gttcttgcgc agtggccgcc attggcaccc tggaaggcag ccccccagtt 3600

 catttcagcc ttccagtgct acacccactt cttggctgac acacttctgc 3650

 tctaagagtc tccctccctt tatagaatgt caaccaaaga gtgccctcct 3700

 cccctctcag cctcctcttt agctagcctc cccatctcat cacaacgcat 3750

 gtctgtgacc tttggtaatc atttacagtg ccacacggaa ccctgtattt 3800

 tgcacacagc aaaacaaaca atgtttagct ttatttatgg tatttgatgc 3850

 tgtaaatgga aataaatatt gttctttata aagct 3885

<210> 2592
<211> 1124
<212> PRT
<213> Homo sapien

<400> 2592
 Met Gly Glu Asn Glu Asp Glu Lys Gln Ala Gln Ala Gly Gln Val
   1               5                  10                  15

 Phe Glu Asn Phe Val Gln Ala Ser Thr Cys Lys Gly Thr Leu Gln
                  20                  25                  30

 Ala Phe Asn Ile Leu Thr Arg His Leu Asp Leu Asp Pro Leu Asp
                  35                  40                  45

 His Arg Asn Phe Tyr Ser Lys Leu Lys Ser Lys Val Thr Thr Trp
                  50                  55                  60

 Lys Ala Lys Ala Leu Trp Tyr Lys Leu Asp Lys Arg Gly Ser His
                  65                  70                  75

 Lys Glu Tyr Lys Arg Gly Lys Ser Cys Thr Asn Thr Lys Cys Leu
                  80                  85                  90

 Ile Val Gly Gly Gly Pro Cys Gly Leu Arg Thr Ala Ile Glu Leu
                  95                 100                 105

 Ala Tyr Leu Gly Ala Lys Val Val Val Val Glu Lys Arg Asp Ser
                 110                 115                 120

 Phe Ser Arg Asn Asn Val Leu His Leu Trp Pro Phe Thr Ile His
                 125                 130                 135

 Asp Leu Arg Gly Leu Gly Ala Lys Lys Phe Tyr Gly Lys Phe Cys
                 140                 145                 150

 Ala Gly Ser Ile Asp His Ile Ser Ile Arg Gln Leu Gln Leu Ile
                 155                 160                 165

 Leu Phe Lys Val Ala Leu Met Leu Gly Val Glu Ile His Val Asn
                 170                 175                 180

 Val Glu Phe Val Lys Val Leu Glu Pro Pro Glu Asp Gln Glu Asn
                 185                 190                 195

 Gln Lys Ile Gly Trp Arg Ala Glu Phe Leu Pro Thr Asp His Ser
                 200                 205                 210

 Leu Ser Glu Phe Glu Phe Asp Val Ile Ile Gly Ala Asp Gly Arg
                 215                 220                 225

 Arg Asn Thr Leu Glu Gly Phe Arg Arg Lys Glu Phe Arg Gly Lys
                 230                 235                 240

 Leu Ala Ile Ala Ile Thr Ala Asn Phe Ile Asn Arg Asn Ser Thr
                 245                 250                 255

 Ala Glu Ala Lys Val Glu Glu Ile Ser Gly Val Ala Phe Ile Phe
                 260                 265                 270

 Asn Gln Lys Phe Phe Gln Asp Leu Lys Glu Glu Thr Gly Ile Asp
                 275                 280                 285

 Leu Glu Asn Ile Val Tyr Tyr Lys Asp Cys Thr His Tyr Phe Val
                 290                 295                 300

 Met Thr Ala Lys Lys Gln Ser Leu Leu Asp Lys Gly Val Ile Ile
                 305                 310                 315

 Asn Asp Tyr Ile Asp Thr Glu Met Leu Leu Cys Ala Glu Asn Val
                 320                 325                 330

 Asn Gln Asp Asn Leu Leu Ser Tyr Ala Arg Glu Ala Ala Asp Phe
                 335                 340                 345

 Ala Thr Asn Tyr Gln Leu Pro Ser Leu Asp Phe Ala Met Asn His
                 350                 355                 360

 Tyr Gly Gln Pro Asp Val Ala Met Phe Asp Phe Thr Cys Met Tyr
                 365                 370                 375

 Ala Ser Glu Asn Ala Ala Leu Val Arg Glu Arg Gln Ala His Gln
                 380                 385                 390

 Leu Leu Val Ala Leu Val Gly Asp Ser Leu Leu Glu Pro Phe Trp
                 395                 400                 405

 Pro Met Gly Thr Gly Cys Ala Arg Gly Phe Leu Ala Ala Phe Asp
                 410                 415                 420

 Thr Ala Trp Met Val Lys Ser Trp Asn Gln Gly Thr Pro Pro Leu
                 425                 430                 435

 Glu Leu Leu Ala Glu Arg Glu Ser Leu Tyr Arg Leu Leu Pro Gln
                 440                 445                 450

 Thr Thr Pro Glu Asn Ile Asn Lys Asn Phe Glu Gln Tyr Thr Leu
                 455                 460                 465

 Asp Pro Gly Thr Arg Tyr Pro Asn Leu Asn Ser His Cys Val Arg
                 470                 475                 480

 Pro His Gln Val Lys His Leu Tyr Ile Thr Lys Glu Leu Glu His
                 485                 490                 495

 Tyr Pro Leu Glu Arg Leu Gly Ser Val Arg Arg Ser Val Asn Leu
                 500                 505                 510

 Ser Arg Lys Glu Ser Asp Ile Arg Pro Ser Lys Leu Leu Thr Trp
                 515                 520                 525

 Cys Gln Gln Gln Thr Glu Gly Tyr Gln His Val Asn Val Thr Asp
                 530                 535                 540

 Leu Thr Thr Ser Trp Arg Ser Gly Leu Ala Leu Cys Ala Ile Ile
                 545                 550                 555

 His Arg Phe Arg Pro Glu Leu Ile Asn Phe Asp Ser Leu Asn Glu
                 560                 565                 570

 Asp Asp Ala Val Glu Asn Asn Gln Leu Ala Phe Asp Val Ala Glu
                 575                 580                 585

 Arg Glu Phe Gly Ile Pro Pro Val Thr Thr Gly Lys Glu Met Ala
                 590                 595                 600

 Ser Ala Gln Glu Pro Asp Lys Leu Ser Met Val Met Tyr Leu Ser
                 605                 610                 615

 Lys Phe Tyr Glu Leu Phe Arg Gly Thr Pro Leu Arg Pro Val Asp
                 620                 625                 630

 Ser Trp Arg Lys Asn Tyr Gly Glu Asn Ala Asp Leu Ser Leu Ala
                 635                 640                 645

 Lys Ser Ser Ile Ser Asn Asn Tyr Leu Asn Leu Thr Phe Pro Arg
                 650                 655                 660

 Lys Arg Thr Pro Arg Val Asp Gly Gln Thr Gly Glu Asn Asp Met
                 665                 670                 675

 Asn Lys Arg Arg Arg Lys Gly Phe Thr Asn Leu Asp Glu Pro Ser
                 680                 685                 690

 Asn Phe Ser Ser Arg Ser Leu Gly Ser Asn Gln Glu Cys Gly Ser
                 695                 700                 705

 Ser Lys Glu Gly Gly Asn Gln Asn Lys Val Lys Ser Met Ala Asn
                 710                 715                 720

 Gln Leu Leu Ala Lys Phe Glu Glu Ser Thr Arg Asn Pro Ser Leu
                 725                 730                 735

 Met Lys Gln Glu Arg Arg Val Ser Gly Ile Gly Lys Pro Val Leu
                 740                 745                 750

 Cys Ser Ser Ser Gly Pro Pro Val His Ser Cys Cys Pro Lys Pro
                 755                 760                 765

 Glu Glu Ala Thr Pro Ser Pro Ser Pro Pro Leu Lys Arg Gln Phe
                 770                 775                 780

 Pro Ser Val Val Val Thr Gly His Val Leu Arg Glu Leu Lys Gln
                 785                 790                 795

 Val Ser Ala Gly Ser Glu Cys Leu Ser Arg Pro Trp Arg Ala Arg
                 800                 805                 810

 Ala Lys Ser Asp Leu Gln Leu Gly Gly Thr Glu Asn Phe Ala Thr
                 815                 820                 825

 Leu Pro Ser Thr Arg Pro Arg Ala Gln Ala Leu Ser Gly Val Leu
                 830                 835                 840

 Trp Arg Leu Gln Gln Val Glu Glu Lys Ile Leu Gln Lys Arg Ala
                 845                 850                 855

 Gln Asn Leu Ala Asn Arg Glu Phe His Thr Lys Asn Ile Lys Glu
                 860                 865                 870

 Lys Ala Ala His Leu Ala Ser Met Phe Gly His Gly Asp Phe Pro
                 875                 880                 885

 Gln Asn Lys Leu Leu Ser Lys Gly Leu Ser His Thr His Pro Pro
                 890                 895                 900

 Ser Pro Pro Ser Arg Leu Pro Ser Pro Asp Pro Ala Ala Ser Ser
                 905                 910                 915

 Ser Pro Ser Thr Val Asp Ser Ala Ser Pro Ala Arg Lys Glu Lys
                 920                 925                 930

 Lys Ser Pro Ser Gly Phe His Phe His Pro Ser His Leu Arg Thr
                 935                 940                 945

 Val His Pro Gln Leu Thr Val Gly Lys Val Ser Ser Gly Ile Gly
                 950                 955                 960

 Ala Ala Ala Glu Val Leu Val Asn Leu Tyr Met Asn Asp His Arg
                 965                 970                 975

 Pro Lys Ala Gln Ala Thr Ser Pro Asp Leu Glu Ser Met Arg Lys
                 980                 985                 990

 Ser Phe Pro Leu Asn Leu Gly Gly Ser Asp Thr Cys Tyr Phe Cys
                 995                1000                1005

 Lys Lys Arg Val Tyr Val Met Glu Arg Leu Ser Ala Glu Gly His
                1010                1015                1020

 Phe Phe His Arg Glu Cys Phe Arg Cys Ser Ile Cys Ala Thr Thr
                1025                1030                1035

 Leu Arg Leu Ala Ala Tyr Thr Phe Asp Cys Asp Glu Gly Lys Phe
                1040                1045                1050

 Tyr Cys Lys Pro His Phe Ile His Cys Lys Thr Asn Ser Lys Gln
                1055                1060                1065

 Arg Lys Arg Arg Ala Glu Leu Lys Gln Gln Arg Glu Glu Glu Ala
                1070                1075                1080

 Thr Trp Gln Glu Gln Glu Ala Pro Arg Arg Asp Thr Pro Thr Glu
                1085                1090                1095

 Ser Ser Cys Ala Val Ala Ala Ile Gly Thr Leu Glu Gly Ser Pro
                1100                1105                1110

 Pro Val His Phe Ser Leu Pro Val Leu His Pro Leu Leu Gly
                1115                1120

<210> 2593
<211> 6926
<212> DNA
<213> Homo sapien

<400> 2593
 cggaggcagg atgaagatga ctgtggattt cgaggagtgt ctgaaggact 50

 cgccccgctt cagggcagct ttggaagaag tagaaggtga tgtggcagaa 100

 ttggaactaa aacttgataa gcttgtgaaa ctttgtattg caatgattga 150

 tactggaaaa gccttttgtg ttgcaaataa acagttcatg aatgggattc 200

 gagacctggc tcagtattct agtaatgatg ctgtcgttga gacaagtttg 250

 accaagtttt ctgacagtct tcaagaaatg ataaattttc acacaatcct 300

 gtttgaccaa actcagagat caattaaggc acagcttcag aactttgtta 350

 aagaagatct tagaaaattc aaagatgcca agaagcaatt cgaaaaagtc 400

 agtgaagaaa aagaaaatgc gttagtaaaa aatgcccaag tacaaagaaa 450

 caaacaacat gaagttgaag aagccaccaa cattctgaca gcaacaagaa 500

 aatgtttccg acacatagcc ctcgattatg tgcttcagat taatgttctt 550

 caatcaaaaa ggagatcaga aatcctaaaa tcaatgttgt catttatgta 600

 tgcccatttg gccttctttc atcaaggata tgatctgttt agtgaacttg 650

 gaccctacat gaaggatctt ggtgcacagt tggatcgact ggttgtggat 700

 gcagcaaagg agaaaagaga aatggagcaa aaacattcca ccattcaaca 750

 aaaggatttc tccagtgatg attctaagtt agaatataac gtagatgctg 800

 caaatggcat agttatggaa ggatatctgt tcaaacgagc cagcaatgcc 850

 ttcaaaactt ggaacaggcg ctggttttca atacagaata atcagttggt 900

 ttaccagaaa aaatttaagg ataatccgac tgtggtagtt gaagacctca 950

 ggctttgcac agtgaaacat tgtgaagaca tagagcgacg attctgcttt 1000

 gaggtggtct cgccaacaaa aagttgcatg ctccaggcag attccgaaaa 1050

 gctgcgccag gcatggatta aggctgttca gaccagtatt gctactgctt 1100

 atagagagaa gggtgatgaa tcagagaagc tggataagaa atcatctcca 1150

 tccacaggaa gcctagattc tggaaatgag tccaaagaga aattattgaa 1200

 aggagaaagt gcgcttcagc gggtccagtg tatccctggc aatgccagct 1250

 gttgtgactg tggcctggca gatccacggt gggccagcat caacctgggc 1300

 atcaccttgt gtatcgagtg ctccggaatt caccggagcc ttggggttca 1350

 tttttcaaaa gtacgatctt taactttaga cacctgggag ccagaacttt 1400

 taaagcttat gtgtgagttg gggaatgatg ttataaatcg agtttatgaa 1450

 gctaatgtgg aaaaaatggg aataaagaaa ccccaaccag gacaaagaca 1500

 ggagaaggag gcatatatca gagcaaaata tgtggagagg aaatttgtgg 1550

 ataaatattc tatatcatta tcacctcctg agcagcaaaa aaagtttgtc 1600

 tctaaaagtt ctgaagaaaa gaggctgagc atttctaaat ttgggccagg 1650

 ggaccaagtc agagcatctg cccaaagttc agtcagaagt aatgacagtg 1700

 gaattcagca gagctctgat gatggaagag aatctttacc ctccacggtg 1750

 tcagccaata gtttatatga gcctgaagga gaaaggcaag attcttctat 1800

 gtttcttgac tcgaaacatc ttaatccagg acttcagctt tatagggcgt 1850

 catatgaaaa aaaccttcct aaaatggctg aggctttggc tcatggtgca 1900

 gacgtgaact gggccaattc agaggaaaac aaagcgacac cacttattca 1950

 ggctgtatta gggggctctt tggtgacgtg tgagttcctc ctacagaatg 2000

 gtgctaatgt caaccaaaga gatgtccaag ggcggggacc attgcaccat 2050

 gccaccgtct tagggcacac agggcaggta tgtttattcc taaaacgagg 2100

 tgccaatcaa catgccactg atgaagaagg gaaagaccct ttgagcatag 2150

 ctgtggaagc agccaatgct gatatagtca ccttgttacg tttagcaaga 2200

 atgaatgaag agatgcggga atcagaagga ctttatggac agccaggtga 2250

 tgaaacttat caggacatat ttcgtgattt ttcccaaatg gcatccaata 2300

 atccagagaa actaaatcgt ttccagcaag attcacagaa attctgaatt 2350

 tttttaaaaa tgggaaaata tgaaatctgg tgacccccta atgtatacag 2400

 ctaaaaattc acaatttttt tactgcttta attctactta attttggtag 2450

 atattgaatg gcttggaaaa gaggtaccca ttcatatatt tataaattaa 2500

 aacatagtta tctagtagta ggagaggaac ctagtttagg acctctttta 2550

 ttaaaaaagc ctatttaaag ggctatttct gtagacagaa gttcagtcta 2600

 gatttaggcc atctctaggt tacaagatga taggaggtta gacaaaagtg 2650

 attcttttgc caatgggtgg tggcattgat ttttttcctc catgcatctt 2700

 gcccaggatc actcagtcaa gcatgtcttc atcaagtgga agccaactgt 2750

 cctgcctgcc tcaagaatat gtgttttctt tagcttccct gaggattttt 2800

 ggtggttcag aaataggtgt gtgtgttgat gtgtttttgg taacctagct 2850

 ttcatacaca taatatatga tttattagaa ctagagaatg tgttttcccc 2900

 gtttgttcat aaatgcggtc ggttatactt cttaggtgac aggttattgt 2950

 ccagtacttt aatgtatgta tgtataatgg ctgtacaggt agaccataat 3000

 tcagtccttt agatttattt tatgcagcaa aaagaagctc tttttttttt 3050

 taatcacaaa aaaaaacccc agttcaaaat gtgtagttct tcattgttgg 3100

 gttgattccc caaaaccttg acagatgtat cgatggaata aaagtatgtt 3150

 ttaaaggtta cttgaatgtc acaaaattat gccttcatca aaactttaaa 3200

 ggaaaaatca atttataaaa tcatgtaggc catttttata tttgaaattt 3250

 gtccttttaa agatagtttt gctgttgctc ctagtgaaag aaaaatctct 3300

 gtacaaagga gaaaaagaac cccacttatt cttagttaat actaaaatat 3350

 atagcaataa attgctgttt attttttcta catctatttt gtgtacttgt 3400

 acacagtgta cattctttta aattatatcg tgtatatagc tttagtattc 3450

 ggttacatga ttcacagacc cctgaattcc aaaatattat ggataaacat 3500

 taccatttat atgctacaaa ttagtctgat tccatctttg aaaatgtctt 3550

 aaagtataaa ataattaatt tgcttttttt ttttttttcc cgagatggcg 3600

 tcttgctgtg tcacccaggc tggagtgcag tggcacgatc tcagctcact 3650

 gcagcctcct cctcttgggt tcaagcaatt ctcctgcctc agcctcccga 3700

 gtagctggga ctacaggcac ccgccaccat tccgagctaa tttctatatt 3750

 tttagtaaag acgggtttca ccattttggc caggttggtc tcgaactcct 3800

 gacctcaggt gatcagcctg ctttagcctc ccagagtgct gggattacag 3850

 gcgtgagcca ccgcacccag cctaatttgc cttttgattc cttcccattg 3900

 ttgtcaaaaa ttaagtctat tcttctttta gaaattatat gtaaatgata 3950

 ttattgatac tctttctaaa taagaggttt taaaatatat aaaaacttta 4000

 tgatccaatt atagataaat tttctaacat ttcccagtca ctagggtttt 4050

 ataagttgat taaacatcaa atcagaatct agccaagcag gaattatatt 4100

 gaaataagtt cacattacag aaaaggttcc ataatttggc caaactgcat 4150

 gcatgtaatg cttatttagt aatggtcact gtatgttaga taaggataaa 4200

 aatatatttg tgaattactt ctgaggaaat gctaacttcc acagcattgt 4250

 atttaattat aacaataaca ggaacattaa atctttatct ttgctgtttc 4300

 acctcaaagt catagatcat ctggcttttt aggcaccttc actaaaggca 4350

 aaaatctgat ttgtagtttt tattagcatg taccttgaaa ttatttgacc 4400

 aagaagctca aagaaaagaa gtacgttaaa gaaaaagaaa aaacctcact 4450

 tttcctttat agtgtccctt cctgttttaa ttcctaaaga tcctgacttt 4500

 tatctgagga agtctaggta gttttccttt tggatctggc cattggtgcg 4550

 tgtttcattc agatcacctc tggaatctct gtggttgtga aggcaattcc 4600

 ttatgagact cttgcctcct gtggcttacg tgatgaattg ttaatatggc 4650

 agtaattaat tagtatctac ttaaatttag tggtcagaaa tgtatttgaa 4700

 gtgccttaaa gatgatcatg gttcagaata tcttcagaga aagcaaaatc 4750

 tttaatattg cagggagcct agcaatacaa atacacattt ctgtggcttg 4800

 atttcttgaa tatgctgaga cccaatttgg actacatttg gcagaaatca 4850

 tggagtaaac agcaaggctt taaattaaat taatagttac aaggtaggtt 4900

 ggctcttagg tgaatttagc catgtcaact aatagctttt atatggtatg 4950

 taacaaatct gaattatgtt atgctgtgaa ttattcagtg cattataaga 5000

 aatcttagtt aatcatgctt ttgggcttca ttagtcaatg tgattggcct 5050

 tttattttct ttccataact tatctgctat tattagtttc ttattcctta 5100

 ttattaatct gttagctcat tatcattagc ttactaactt gaaagttaga 5150

 ttaatatcaa aataagaata gcagcactat gaagagttaa taaaatgcaa 5200

 tttcatgtta gagctagaat aaaagtaatt gagcagtcat ttgcaaatgc 5250

 ttcattataa catttatgtg cttaagattt ctaaggtttt aaaaagttac 5300

 ctttaataca atccttagaa actcagaaat ttcctgatat tcattagatt 5350

 atggtgtttg cctaatttat accggttttc actgtatatt ttaatgaact 5400

 ttgattggtt acttttccag acatacagat ttaatttgga atatgaactt 5450

 tggttcttca tgagtgcatt ttgaaaaaga aaaaaagtac acattcagaa 5500

 tctggccaat ttaagtttgt attttaaaaa tattttatgc atgttaagta 5550

 tggtcgcagt aaatgaaatt gtgtttaaga ctaaatttac taccgttttg 5600

 aacagacatt cccagatcat tcttatattg tcagataaca cttgtgtata 5650

 atatcacttt ggaccatgga catgagctgg aaaaatgatg tatttttgta 5700

 gattgtatgt ccagaatgac tttagaaccg catgatacgg tggaaggagc 5750

 actggactag tcgtcactac cctttttgga ttcagggctc ctcacaatta 5800

 aaatgagtgt aatgaaacaa ggtgaaaata tagaagcatc cctttgtata 5850

 ctgttttgct acttacagtg tacttggcat tgctttatct cactggattc 5900

 tcatggtagg atttctgaga tcttaatcta agctccaaag ttgtctactt 5950

 ttttgatcct agggtgctcc ttttgtttta cagagcaggg tcacttgatt 6000

 tgctagctgg tggcagaatt ggcaccatta cccaggtctg actgaccacc 6050

 agtcagaggc actttatttg tatcatgaaa tgatttgaaa tcattgtaaa 6100

 gcagcgaagt ctgataatga atgccagctt tccttgtgct ttgataacaa 6150

 agactccaaa tattctggag aacctggata aaagtttgaa gggctagatt 6200

 gggatttgaa gacaaaattg taggaaatct tacatttttg caataacaaa 6250

 cattaatgaa agcaaaacat tataaaagta attttaattc accacatact 6300

 tatcaatttc ttgatgcttc caaatgacat ctacagatat ggttttgtgg 6350

 acatcttttt ctgtttacat aaatttatcc acttaaaatg tgataatgtg 6400

 gagacaaagc aagatttgat tacataaact tttctctgca ttggtctttt 6450

 cactatctta tttgctaact tttcttattt ttcttcaacc tccccaccct 6500

 ccattttttg gatattaaac agggaaagct tgctacatta taaagattgt 6550

 tggcaccatt tattttacac aaaggctaaa ggttaacttt tggaaatgat 6600

 gagctacttt tatatatgtg tttactcatg ctttgtgata tttctggatc 6650

 attccagtca taaagactta ttacatgtac tatttcttgc tacctgtgaa 6700

 aaggtatatt ttaaagaatg tataaccaac agtccattta ctttttatta 6750

 gtatgtagag gatttgtatc taattcatga atgtagtttt acagtagttt 6800

 gtcattgtaa atggagcaaa gtacattatc ttctaaaatg tacattatgt 6850

 aagaattgta aatatactta agtaatttgt atgccaaaaa attacaataa 6900

 gtcaataaag atctcacctc tggctt 6926

<210> 2594
<211> 8124
<212> DNA
<213> Homo sapien

<400> 2594
 gtttgtcgca gcaagaacaa acagcattcc ttccagcaaa tcaagtgcct 50

 gttttacaac agaacacttc agttgctgca aaacaacccc agacttctgt 100

 ggtacagaat caacaacaga tatcacaaca gggacctata tatgatgaag 150

 tggaattgga tgcattggct gaaattgagc gaatagagag agaatcagct 200

 attgaaaggg agcgcttctc aaaagaagtt caagataaag ataagccttt 250

 gaaaaaaaga aaacaagatt cttacccaca ggaggctggg ggtgctacag 300

 gaggtaatag accagcttct caggagacgg gttctacggg aaatgggtca 350

 aggccagcat taatggttag cattgatctt catcaggcag gaagagtgga 400

 ctctcaggct tctataactc aggattcaga ctccataaaa aagcctgaag 450

 aaatcaaaca atgtaatgat gcacctgttt ctgttcttca ggaagatatt 500

 gttggaagtc ttaaatctac accagaaaac catcctgaga cacctaaaaa 550

 aaagtctgat cctgagcttt caaagagtga aatgaaacaa agtgaaagta 600

 gattagcaga atctaaacca aatgaaaacc gattggtgga gacaaaatca 650

 agtgaaaata agttagaaac taaagttgag acccaaacag aagaacttaa 700

 acagaatgag agcagaacaa ctgaatgcaa acaaaacgag agcaccatag 750

 ttgagcctaa acaaaatgaa aatagactgt ctgacacaaa accaaatgac 800

 aacaaacaaa ataatggcag atcagaaaca acaaaatcaa ggcctgaaac 850

 cccaaagcaa aagggtgaaa gccggcctga gactccaaaa caaaagagtg 900

 atgggcatcc tgaaacccca aaacagaagg gtgatggaag gcctgaaact 950

 ccaaagcaaa aaggtgagag ccgccctgaa actccaaagc aaaaaaatga 1000

 agggcgacct gaaacaccaa aacacaggca tgacaatagg agggattctg 1050

 gaaagccatc tacagagaaa aaacctgaag tgtctaaaca taaacaagat 1100

 actaaatctg actcacctcg gttaaaatca gaacgagctg aagccttaaa 1150

 gcagagacct gatgggcgat ctgtttctga gtcactaaga cgtgaccatg 1200

 ataataaaca aaaatcagat gacaggggtg aatcagagcg acatcgaggg 1250

 gatcagtcta gggttcgaag accagaaaca ttgagatcct ctagtagaaa 1300

 tgaacatggc attaaatctg atagttcaaa aactgataaa ctagaacgaa 1350

 aacacaggca tgaatcaggg gactcaaggg aaagaccatc ttctggggaa 1400

 caaaaatcaa gacctgacag tcctcgtgtt aaacaaggag attctaataa 1450

 atcaagatct gataaacttg gttttaaatc accaactagt aaagatgaca 1500

 aaaggacaga gggtaacaag agtaaagtag acactaataa agcacaccct 1550

 gacaataagg cagaatttcc aagttatttg ttggggggca ggtctggtgc 1600

 gttgaaaaat tttgtcattc cgaaaatcaa gagggataaa gatggcaatg 1650

 ttactcagga gacaaagaaa atggaaatga aaggagagcc gaaagacaaa 1700

 gtagaaaaaa taggattagt tgaagatcta aataaaggag ctaagcctgt 1750

 agttgtgcta caaaaactgt ctttggatga tgttcagaaa cttattaaag 1800

 atagagagga caaatcaaga agttccctta aacctatcaa gaataaacca 1850

 tcaaagtcaa ataaaggtag tatagatcaa tcagtgttaa aagaattacc 1900

 ccctgaactc ctggcagaaa ttgagtccac catgccactt tgtgaacgtg 1950

 tgaaaatgaa caaacgcaag cgtagcacag ttaatgaaaa gccaaaatat 2000

 gctgaaatca gttcagatga agataatgat agtgatgaag cttttgaatc 2050

 ctctaggaaa cgacataaaa aagatgatga taaagcttgg gaatatgaag 2100

 agcgtgacag aagaagctct ggggatcata ggagaagtgg ccactctcat 2150

 gaaggaagaa ggagttcagg tggtggtcgt tatcgaaacc gaagtccgtc 2200

 agattctgac atggaagatt attctcctcc tcccagcctt agtgaggttg 2250

 ctaggaaaat gaagaaaaaa gaaaaacaga agaaaaggaa agcatatgaa 2300

 ccaaaactaa cacctgaaga aatgatggac tcttcaactt ttaagagatt 2350

 cacagcctca atagagaata ttttggataa tttggaagat atggatttta 2400

 ctgcgtttgg tgatgatgat gaaattcctc aggaactgct cttaggaaaa 2450

 catcagctta atgaacttgg cagtgaatct gctaaaataa aagcaatggg 2500

 tataatggat aagctttcaa ctgacaaaac tgtgaaagtc ttaaatatct 2550

 tggagaagaa tattcaggat gggtcaaagc tttccacttt gttaaatcat 2600

 aataacgata ctgaagaaga agaaaggtta tggagagacc ttattatgga 2650

 gagagttaca aaatcagcgg atgcttgtct tacaactatc aacattatga 2700

 catcccctaa catgccaaaa gctgtgtaca ttgaggatgt aattgaaaga 2750

 gttatacagt acactaaatt tcatttgcag aatacacttt atcctcagta 2800

 tgatcctgtt tacagattag atcctcatgg aggaggctta ttaagttcaa 2850

 aagcaaaacg ggctaaatgt tctacccata agcagagagt aatagtaatg 2900

 ctttataaca aagtttgtga cattgttagc agcttatcag aattgctaga 2950

 gatacaactt cttacagaca caacaattct tcaggtttca tctatgggaa 3000

 taacaccatt ttttgtggaa aatgtcagtg aactacagtt gtgtgccatt 3050

 aagttagtca ctgcagtatt ctcaagatat gaaaaacata ggcagttaat 3100

 tttggaagaa atttttactt cacttgcaag attaccaacc agcaagagga 3150

 gtttaaggaa cttcaggtta aacagtagtg atatggatgg agaacctatg 3200

 tatattcaga tggttacagc actggtttta caacttattc agtgtgtggt 3250

 acacttacca tcatcagaga aggactctaa tgcagaagaa gattcaaata 3300

 aaaaaattga ccaggatgtt gtcattacta actcttatga aacagctatg 3350

 cgaacagccc aaaacttcct ctccatcttc cttaaaaaat gtggtagtaa 3400

 gcaaggtgaa gaagattaca gaccactgtt tgaaaatttt gttcaagacc 3450

 ttctttcaac agtcaataag cctgaatggc cagctgctga actactcctt 3500

 agtttgttag ggagactgtt ggttcatcag ttcagtaaca agtcaacaga 3550

 gatggcttta agagtggcat ctcttgatta ccttggaact gttgctgcac 3600

 ggctaagaaa agatgctgtt acaagcaaaa tggatcaagg atctatagaa 3650

 cgcattttaa aacaggtttc aggaggggaa gatgaaatcc aacaattaca 3700

 aaaagcattg cttgattact tggatgaaaa cactgagact gatccttcac 3750

 tagtgttttc tcgtaaattc tatatagccc agtggtttcg agacacaact 3800

 ctggaaacag aaaaagcaat gaaatcacaa aaagatgaag aatcatctga 3850

 aggaacacat catgcaaagg aaattgagac aactggccaa attatgcatc 3900

 gagctgaaaa ccgaaaaaag tttcttagaa gcattatcaa aaccacacct 3950

 tctcagttta gcacattaaa gatgaactct gatactgtgg actatgatga 4000

 tgcttgcttg attgttcgat acttggcctc catgaggccg tttgcccaga 4050

 gctttgatat ttatttgaca cagatcctac gagttcttgg tgaaaatgca 4100

 attgctgttc gaacaaaagc catgaagtgt ttgtctgagg ttgttgctgt 4150

 agaccccagt attctagcaa ggcttgatat gcaacgaggt gttcatggac 4200

 gattgatgga taattcgact agtgtccgag aagcagcagt agaattacta 4250

 ggtcgatttg tcctttgtcg acctcagctt gctgaacagt attatgatat 4300

 gctgattgaa agaatattgg atactggtat cagtgtcagg aaaagagtaa 4350

 taaagattct cagagacatt tgtattgaac aaccaacatt tccaaaaatc 4400

 acagaaatgt gtgtaaaaat gattcgcaga gtcaatgatg aagagggcat 4450

 taagaaatta gtaaatgaaa cattccagaa actctggttt actccaactc 4500

 cacacaatga caaagaagca atgacaagga aaattttaaa cattaccgat 4550

 gtggttgcag catgcagaga tactggatat gactggtttg agcaactgct 4600

 tcaaaacttg ttgaagtccg aagaggattc ctcatataaa cctgtgaaga 4650

 aagcttgtac tcaacttgtt gataacctag ttgagcacat tcttaaatat 4700

 gaggaatctc tagctgactc tgacaataaa ggtgtgaatt ctggaagatt 4750

 ggtagcttgc ataaccactt tgttcttatt cagcaaaata agaccccagc 4800

 tcatggttaa acatgcaatg actatgcaac cataccttac cactaaatgt 4850

 agtacgcaaa atgatttcat ggttatctgc aatgttgcaa aaatcctaga 4900

 gctagttgta ccactgatgg agcatccaag tgaaactttt cttgccacta 4950

 ttgaggaaga tctaatgaag ctcatcatca aatatggcat gactgtagtg 5000

 caacattgtg tgagctgtct tggagctgtt gtaaataaag tgacacaaaa 5050

 ttttaaattt gtgtgggctt gtttcaatag atactatggt gccatttcaa 5100

 aattaaaaag tcaacaccaa gaggacccaa ataacacttc acttctaaca 5150

 aacaaaccag cacttcttag atcccttttc accgttggag cactatgtcg 5200

 gcattttgat tttgatctgg aagattttaa aggcaacagc aaggttaaca 5250

 taaaagataa agtacttgaa ctattgatgt attttacaaa acactcagat 5300

 gaagaagtac aaacaaaagc tatcattggt ctaggatttg cctttattca 5350

 gcatccaagt ctaatgttcg agcaagaagt gaagaatcta tataataata 5400

 ttttatctga taagaactcc tcagtcaatt taaaaataca agtgttaaaa 5450

 aacctccaga cctacctaca agaagaagat acacgtatgc agcaggcaga 5500

 tagagactgg aagaaagttg caaaacagga agacttaaaa gaaatgggtg 5550

 atgtttcctc agggatgagt agttccatca tgcagcttta tctcaaacag 5600

 gtgcttgagg cattttttca cacccagtca agtgtacgcc actttgccct 5650

 aaatgtcatt gcattgactc taaatcaagg tcttattcat ccagttcagt 5700

 gtgtgccata tttaattgct atgggcacag acccagaacc tgctatgcgg 5750

 aacaaggctg atcagcaact tgtggaaata gacaaaaaat atgctggatt 5800

 cattcatatg aaagcagtgg ctggtatgaa gatgtcttac caggtacaac 5850

 aggcaatcaa cacatgccta aaagatcctg taaggggttt cagacaagac 5900

 gagtcctcta gcgctttgtg ttcacacctt tactccatga tccgtggaaa 5950

 ccgccaacac agacgagcct ttcttatttc tttactcaac ctctttgatg 6000

 acacagcaaa aacagacgtg actatgctct tgtatatagc agacaatcta 6050

 gcctgttttc cataccagac acaggaagag ccgttgttta taatgcatca 6100

 tatagacatt acactctcag tttctggtag taacctactg cagtcattca 6150

 aggagtctat ggtaaaggac aaaaggaaag agagaaaatc atcacctagt 6200

 aaggaaaatg agtcaagcga cagtgaagaa gaagtttcca ggcctcggaa 6250

 gtcacggaaa cgtgtagatt cagattcaga ttcagattca gaagacgata 6300

 taaattcagt gatgaaatgt ttgccagaaa attcagctcc tttaatcgaa 6350

 tttgcaaatg tgtcccaggg tattttatta cttctcatgt taaaacaaca 6400

 tttgaagaat ctttgtggat tttctgatag taaaattcag aagtactctc 6450

 catctgaatc tgcaaaagta tatgataaag cgataaaccg aaaaacagga 6500

 gttcattttc atccaaaaca aacactggac ttcctgcgga gtgacatggc 6550

 taattccaaa atcacagaag aggtgaaaag gagtatagta aaacagtatc 6600

 tagatttcaa acttctcatg gaacatctgg accctgatga agaagaagaa 6650

 gaaggggagg tttcagctag cacaaatgct cggaacaaag caattacctc 6700

 actgcttgga ggaggcagcc ctaaaaataa tacagcagca gagacagaag 6750

 atgatgaaag tgatggggag gatagaggag gaggcacttc agggtcattg 6800

 agaaggtcaa aacgaaattc agactctacg gagttggcag cacagatgaa 6850

 tgaaagtgtt gacgtcatgg atgtcatcgc tatttgctgt ccaaagtaca 6900

 aagatcgacc acaaattgca agagtagtgc agaaaaccag cagtggcttc 6950

 agtgttcagt ggatggcagg ctcctacagt ggctcctgga ctgaggctaa 7000

 gcgccgtgat ggccgcaaac tggtgccttg ggtagacact attaaagagt 7050

 cagacattat ttacaaaaaa attgctctaa cgagtgctaa taagctgact 7100

 aataaagttg ttcagacttt acgatccctg tatgccgcca aggatgggac 7150

 ttccagctaa tgaatttgta catgcagcca aatttacagg aatttttttt 7200

 aaaaggcaga aaaacttgaa ataccaacat tctggcaaaa aaaaatcagt 7250

 tttatgaaga gtaagtggaa cctgggatgc aggaacaaaa gaaggaaatg 7300

 ttgggcaaac atttttgtgg gagctccctt cgctgttgtg cagcagaaac 7350

 agattctcag ttcattttta ctcccactgt attatagttt aacaaaaatt 7400

 gtttatatct tggaaaaaaa actttctgtt taaaaaaaat aaacaagtga 7450

 atgttggaaa ttagtctgtt aatgttctta ataaagtgtt cttggagttt 7500

 aacctagcag cggatggctt tctttagctt agcccagttt ccagggaagc 7550

 attgtttttt ccaggctgta aaatggcaga atctcctgga tatataattt 7600

 attctgttga aaaaaaaaaa agcatgcagt atctatgacc tatctgcaga 7650

 aggagttttt gtaaatgtag attttgatgt attaggtcac cctgaaaaca 7700

 atacaagaaa agggatcccc aggtaatctg gtggagcgaa tactgcaata 7750

 aattttttta cttctctttg ttacttgtct gtttccattt gaatttctta 7800

 ttgtaaaaat ctgtttaaat ccatttatat tattttacag tcttttatgt 7850

 aaaatttatt atatcactgg ttttcaaagc aaaacataaa atattgttta 7900

 tacagtttgt ataggctgac ttctgaataa ttggtatcta ttattttcat 7950

 tcccataaga gggtgtaaac aattaactcc agggttttat tgtatcctgc 8000

 aatatttagt attaactata tatgatttag cactgtgcca aacacatttt 8050

 caagagtaca ttttgatata aaaagaaact atagtttaaa aaaaaaaaaa 8100

 aaaaaaaaaa aaaaaaaaaa aaaa 8124

<210> 2595
<211> 2000
<212> PRT
<213> Homo sapien

<400> 2595
 Met Val Ser Ile Asp Leu His Gln Ala Gly Arg Val Asp Ser Gln
   1               5                  10                  15

 Ala Ser Ile Thr Gln Asp Ser Asp Ser Ile Lys Lys Pro Glu Glu
                  20                  25                  30

 Ile Lys Gln Cys Asn Asp Ala Pro Val Ser Val Leu Gln Glu Asp
                  35                  40                  45

 Ile Val Gly Ser Leu Lys Ser Thr Pro Glu Asn His Pro Glu Thr
                  50                  55                  60

 Pro Lys Lys Lys Ser Asp Pro Glu Leu Ser Lys Ser Glu Met Lys
                  65                  70                  75

 Gln Ser Glu Ser Arg Leu Ala Glu Ser Lys Pro Asn Glu Asn Arg
                  80                  85                  90

 Leu Val Glu Thr Lys Ser Ser Glu Asn Lys Leu Glu Thr Lys Val
                  95                 100                 105

 Glu Thr Gln Thr Glu Glu Leu Lys Gln Asn Glu Ser Arg Thr Thr
                 110                 115                 120

 Glu Cys Lys Gln Asn Glu Ser Thr Ile Val Glu Pro Lys Gln Asn
                 125                 130                 135

 Glu Asn Arg Leu Ser Asp Thr Lys Pro Asn Asp Asn Lys Gln Asn
                 140                 145                 150

 Asn Gly Arg Ser Glu Thr Thr Lys Ser Arg Pro Glu Thr Pro Lys
                 155                 160                 165

 Gln Lys Gly Glu Ser Arg Pro Glu Thr Pro Lys Gln Lys Ser Asp
                 170                 175                 180

 Gly His Pro Glu Thr Pro Lys Gln Lys Gly Asp Gly Arg Pro Glu
                 185                 190                 195

 Thr Pro Lys Gln Lys Gly Glu Ser Arg Pro Glu Thr Pro Lys Gln
                 200                 205                 210

 Lys Asn Glu Gly Arg Pro Glu Thr Pro Lys His Arg His Asp Asn
                 215                 220                 225

 Arg Arg Asp Ser Gly Lys Pro Ser Thr Glu Lys Lys Pro Glu Val
                 230                 235                 240

 Ser Lys His Lys Gln Asp Thr Lys Ser Asp Ser Pro Arg Leu Lys
                 245                 250                 255

 Ser Glu Arg Ala Glu Ala Leu Lys Gln Arg Pro Asp Gly Arg Ser
                 260                 265                 270

 Val Ser Glu Ser Leu Arg Arg Asp His Asp Asn Lys Gln Lys Ser
                 275                 280                 285

 Asp Asp Arg Gly Glu Ser Glu Arg His Arg Gly Asp Gln Ser Arg
                 290                 295                 300

 Val Arg Arg Pro Glu Thr Leu Arg Ser Ser Ser Arg Asn Glu His
                 305                 310                 315

 Gly Ile Lys Ser Asp Ser Ser Lys Thr Asp Lys Leu Glu Arg Lys
                 320                 325                 330

 His Arg His Glu Ser Gly Asp Ser Arg Glu Arg Pro Ser Ser Gly
                 335                 340                 345

 Glu Gln Lys Ser Arg Pro Asp Ser Pro Arg Val Lys Gln Gly Asp
                 350                 355                 360

 Ser Asn Lys Ser Arg Ser Asp Lys Leu Gly Phe Lys Ser Pro Thr
                 365                 370                 375

 Ser Lys Asp Asp Lys Arg Thr Glu Gly Asn Lys Ser Lys Val Asp
                 380                 385                 390

 Thr Asn Lys Ala His Pro Asp Asn Lys Ala Glu Phe Pro Ser Tyr
                 395                 400                 405

 Leu Leu Gly Gly Arg Ser Gly Ala Leu Lys Asn Phe Val Ile Pro
                 410                 415                 420

 Lys Ile Lys Arg Asp Lys Asp Gly Asn Val Thr Gln Glu Thr Lys
                 425                 430                 435

 Lys Met Glu Met Lys Gly Glu Pro Lys Asp Lys Val Glu Lys Ile
                 440                 445                 450

 Gly Leu Val Glu Asp Leu Asn Lys Gly Ala Lys Pro Val Val Val
                 455                 460                 465

 Leu Gln Lys Leu Ser Leu Asp Asp Val Gln Lys Leu Ile Lys Asp
                 470                 475                 480

 Arg Glu Asp Lys Ser Arg Ser Ser Leu Lys Pro Ile Lys Asn Lys
                 485                 490                 495

 Pro Ser Lys Ser Asn Lys Gly Ser Ile Asp Gln Ser Val Leu Lys
                 500                 505                 510

 Glu Leu Pro Pro Glu Leu Leu Ala Glu Ile Glu Ser Thr Met Pro
                 515                 520                 525

 Leu Cys Glu Arg Val Lys Met Asn Lys Arg Lys Arg Ser Thr Val
                 530                 535                 540

 Asn Glu Lys Pro Lys Tyr Ala Glu Ile Ser Ser Asp Glu Asp Asn
                 545                 550                 555

 Asp Ser Asp Glu Ala Phe Glu Ser Ser Arg Lys Arg His Lys Lys
                 560                 565                 570

 Asp Asp Asp Lys Ala Trp Glu Tyr Glu Glu Arg Asp Arg Arg Ser
                 575                 580                 585

 Ser Gly Asp His Arg Arg Ser Gly His Ser His Glu Gly Arg Arg
                 590                 595                 600

 Ser Ser Gly Gly Gly Arg Tyr Arg Asn Arg Ser Pro Ser Asp Ser
                 605                 610                 615

 Asp Met Glu Asp Tyr Ser Pro Pro Pro Ser Leu Ser Glu Val Ala
                 620                 625                 630

 Arg Lys Met Lys Lys Lys Glu Lys Gln Lys Lys Arg Lys Ala Tyr
                 635                 640                 645

 Glu Pro Lys Leu Thr Pro Glu Glu Met Met Asp Ser Ser Thr Phe
                 650                 655                 660

 Lys Arg Phe Thr Ala Ser Ile Glu Asn Ile Leu Asp Asn Leu Glu
                 665                 670                 675

 Asp Met Asp Phe Thr Ala Phe Gly Asp Asp Asp Glu Ile Pro Gln
                 680                 685                 690

 Glu Leu Leu Leu Gly Lys His Gln Leu Asn Glu Leu Gly Ser Glu
                 695                 700                 705

 Ser Ala Lys Ile Lys Ala Met Gly Ile Met Asp Lys Leu Ser Thr
                 710                 715                 720

 Asp Lys Thr Val Lys Val Leu Asn Ile Leu Glu Lys Asn Ile Gln
                 725                 730                 735

 Asp Gly Ser Lys Leu Ser Thr Leu Leu Asn His Asn Asn Asp Thr
                 740                 745                 750

 Glu Glu Glu Glu Arg Leu Trp Arg Asp Leu Ile Met Glu Arg Val
                 755                 760                 765

 Thr Lys Ser Ala Asp Ala Cys Leu Thr Thr Ile Asn Ile Met Thr
                 770                 775                 780

 Ser Pro Asn Met Pro Lys Ala Val Tyr Ile Glu Asp Val Ile Glu
                 785                 790                 795

 Arg Val Ile Gln Tyr Thr Lys Phe His Leu Gln Asn Thr Leu Tyr
                 800                 805                 810

 Pro Gln Tyr Asp Pro Val Tyr Arg Leu Asp Pro His Gly Gly Gly
                 815                 820                 825

 Leu Leu Ser Ser Lys Ala Lys Arg Ala Lys Cys Ser Thr His Lys
                 830                 835                 840

 Gln Arg Val Ile Val Met Leu Tyr Asn Lys Val Cys Asp Ile Val
                 845                 850                 855

 Ser Ser Leu Ser Glu Leu Leu Glu Ile Gln Leu Leu Thr Asp Thr
                 860                 865                 870

 Thr Ile Leu Gln Val Ser Ser Met Gly Ile Thr Pro Phe Phe Val
                 875                 880                 885

 Glu Asn Val Ser Glu Leu Gln Leu Cys Ala Ile Lys Leu Val Thr
                 890                 895                 900

 Ala Val Phe Ser Arg Tyr Glu Lys His Arg Gln Leu Ile Leu Glu
                 905                 910                 915

 Glu Ile Phe Thr Ser Leu Ala Arg Leu Pro Thr Ser Lys Arg Ser
                 920                 925                 930

 Leu Arg Asn Phe Arg Leu Asn Ser Ser Asp Met Asp Gly Glu Pro
                 935                 940                 945

 Met Tyr Ile Gln Met Val Thr Ala Leu Val Leu Gln Leu Ile Gln
                 950                 955                 960

 Cys Val Val His Leu Pro Ser Ser Glu Lys Asp Ser Asn Ala Glu
                 965                 970                 975

 Glu Asp Ser Asn Lys Lys Ile Asp Gln Asp Val Val Ile Thr Asn
                 980                 985                 990

 Ser Tyr Glu Thr Ala Met Arg Thr Ala Gln Asn Phe Leu Ser Ile
                 995                1000                1005

 Phe Leu Lys Lys Cys Gly Ser Lys Gln Gly Glu Glu Asp Tyr Arg
                1010                1015                1020

 Pro Leu Phe Glu Asn Phe Val Gln Asp Leu Leu Ser Thr Val Asn
                1025                1030                1035

 Lys Pro Glu Trp Pro Ala Ala Glu Leu Leu Leu Ser Leu Leu Gly
                1040                1045                1050

 Arg Leu Leu Val His Gln Phe Ser Asn Lys Ser Thr Glu Met Ala
                1055                1060                1065

 Leu Arg Val Ala Ser Leu Asp Tyr Leu Gly Thr Val Ala Ala Arg
                1070                1075                1080

 Leu Arg Lys Asp Ala Val Thr Ser Lys Met Asp Gln Gly Ser Ile
                1085                1090                1095

 Glu Arg Ile Leu Lys Gln Val Ser Gly Gly Glu Asp Glu Ile Gln
                1100                1105                1110

 Gln Leu Gln Lys Ala Leu Leu Asp Tyr Leu Asp Glu Asn Thr Glu
                1115                1120                1125

 Thr Asp Pro Ser Leu Val Phe Ser Arg Lys Phe Tyr Ile Ala Gln
                1130                1135                1140

 Trp Phe Arg Asp Thr Thr Leu Glu Thr Glu Lys Ala Met Lys Ser
                1145                1150                1155

 Gln Lys Asp Glu Glu Ser Ser Glu Gly Thr His His Ala Lys Glu
                1160                1165                1170

 Ile Glu Thr Thr Gly Gln Ile Met His Arg Ala Glu Asn Arg Lys
                1175                1180                1185

 Lys Phe Leu Arg Ser Ile Ile Lys Thr Thr Pro Ser Gln Phe Ser
                1190                1195                1200

 Thr Leu Lys Met Asn Ser Asp Thr Val Asp Tyr Asp Asp Ala Cys
                1205                1210                1215

 Leu Ile Val Arg Tyr Leu Ala Ser Met Arg Pro Phe Ala Gln Ser
                1220                1225                1230

 Phe Asp Ile Tyr Leu Thr Gln Ile Leu Arg Val Leu Gly Glu Asn
                1235                1240                1245

 Ala Ile Ala Val Arg Thr Lys Ala Met Lys Cys Leu Ser Glu Val
                1250                1255                1260

 Val Ala Val Asp Pro Ser Ile Leu Ala Arg Leu Asp Met Gln Arg
                1265                1270                1275

 Gly Val His Gly Arg Leu Met Asp Asn Ser Thr Ser Val Arg Glu
                1280                1285                1290

 Ala Ala Val Glu Leu Leu Gly Arg Phe Val Leu Cys Arg Pro Gln
                1295                1300                1305

 Leu Ala Glu Gln Tyr Tyr Asp Met Leu Ile Glu Arg Ile Leu Asp
                1310                1315                1320

 Thr Gly Ile Ser Val Arg Lys Arg Val Ile Lys Ile Leu Arg Asp
                1325                1330                1335

 Ile Cys Ile Glu Gln Pro Thr Phe Pro Lys Ile Thr Glu Met Cys
                1340                1345                1350

 Val Lys Met Ile Arg Arg Val Asn Asp Glu Glu Gly Ile Lys Lys
                1355                1360                1365

 Leu Val Asn Glu Thr Phe Gln Lys Leu Trp Phe Thr Pro Thr Pro
                1370                1375                1380

 His Asn Asp Lys Glu Ala Met Thr Arg Lys Ile Leu Asn Ile Thr
                1385                1390                1395

 Asp Val Val Ala Ala Cys Arg Asp Thr Gly Tyr Asp Trp Phe Glu
                1400                1405                1410

 Gln Leu Leu Gln Asn Leu Leu Lys Ser Glu Glu Asp Ser Ser Tyr
                1415                1420                1425

 Lys Pro Val Lys Lys Ala Cys Thr Gln Leu Val Asp Asn Leu Val
                1430                1435                1440

 Glu His Ile Leu Lys Tyr Glu Glu Ser Leu Ala Asp Ser Asp Asn
                1445                1450                1455

 Lys Gly Val Asn Ser Gly Arg Leu Val Ala Cys Ile Thr Thr Leu
                1460                1465                1470

 Phe Leu Phe Ser Lys Ile Arg Pro Gln Leu Met Val Lys His Ala
                1475                1480                1485

 Met Thr Met Gln Pro Tyr Leu Thr Thr Lys Cys Ser Thr Gln Asn
                1490                1495                1500

 Asp Phe Met Val Ile Cys Asn Val Ala Lys Ile Leu Glu Leu Val
                1505                1510                1515

 Val Pro Leu Met Glu His Pro Ser Glu Thr Phe Leu Ala Thr Ile
                1520                1525                1530

 Glu Glu Asp Leu Met Lys Leu Ile Ile Lys Tyr Gly Met Thr Val
                1535                1540                1545

 Val Gln His Cys Val Ser Cys Leu Gly Ala Val Val Asn Lys Val
                1550                1555                1560

 Thr Gln Asn Phe Lys Phe Val Trp Ala Cys Phe Asn Arg Tyr Tyr
                1565                1570                1575

 Gly Ala Ile Ser Lys Leu Lys Ser Gln His Gln Glu Asp Pro Asn
                1580                1585                1590

 Asn Thr Ser Leu Leu Thr Asn Lys Pro Ala Leu Leu Arg Ser Leu
                1595                1600                1605

 Phe Thr Val Gly Ala Leu Cys Arg His Phe Asp Phe Asp Leu Glu
                1610                1615                1620

 Asp Phe Lys Gly Asn Ser Lys Val Asn Ile Lys Asp Lys Val Leu
                1625                1630                1635

 Glu Leu Leu Met Tyr Phe Thr Lys His Ser Asp Glu Glu Val Gln
                1640                1645                1650

 Thr Lys Ala Ile Ile Gly Leu Gly Phe Ala Phe Ile Gln His Pro
                1655                1660                1665

 Ser Leu Met Phe Glu Gln Glu Val Lys Asn Leu Tyr Asn Asn Ile
                1670                1675                1680

 Leu Ser Asp Lys Asn Ser Ser Val Asn Leu Lys Ile Gln Val Leu
                1685                1690                1695

 Lys Asn Leu Gln Thr Tyr Leu Gln Glu Glu Asp Thr Arg Met Gln
                1700                1705                1710

 Gln Ala Asp Arg Asp Trp Lys Lys Val Ala Lys Gln Glu Asp Leu
                1715                1720                1725

 Lys Glu Met Gly Asp Val Ser Ser Gly Met Ser Ser Ser Ile Met
                1730                1735                1740

 Gln Leu Tyr Leu Lys Gln Val Leu Glu Ala Phe Phe His Thr Gln
                1745                1750                1755

 Ser Ser Val Arg His Phe Ala Leu Asn Val Ile Ala Leu Thr Leu
                1760                1765                1770

 Asn Gln Gly Leu Ile His Pro Val Gln Cys Val Pro Tyr Leu Ile
                1775                1780                1785

 Ala Met Gly Thr Asp Pro Glu Pro Ala Met Arg Asn Lys Ala Asp
                1790                1795                1800

 Gln Gln Leu Val Glu Ile Asp Lys Lys Tyr Ala Gly Phe Ile His
                1805                1810                1815

 Met Lys Ala Val Ala Gly Met Lys Met Ser Tyr Gln Val Gln Gln
                1820                1825                1830

 Ala Ile Asn Thr Cys Leu Lys Asp Pro Val Arg Gly Phe Arg Gln
                1835                1840                1845

 Asp Glu Ser Ser Ser Ala Leu Cys Ser His Leu Tyr Ser Met Ile
                1850                1855                1860

 Arg Gly Asn Arg Gln His Arg Arg Ala Phe Leu Ile Ser Leu Leu
                1865                1870                1875

 Asn Leu Phe Asp Asp Thr Ala Lys Thr Asp Val Thr Met Leu Leu
                1880                1885                1890

 Tyr Ile Ala Asp Asn Leu Ala Cys Phe Pro Tyr Gln Thr Gln Glu
                1895                1900                1905

 Glu Pro Leu Phe Ile Met His His Ile Asp Ile Thr Leu Ser Val
                1910                1915                1920

 Ser Gly Ser Asn Leu Leu Gln Ser Phe Lys Glu Ser Met Val Lys
                1925                1930                1935

 Asp Lys Arg Lys Glu Arg Lys Ser Ser Pro Ser Lys Glu Asn Glu
                1940                1945                1950

 Ser Ser Asp Ser Glu Glu Glu Val Ser Arg Pro Arg Lys Ser Arg
                1955                1960                1965

 Lys Arg Val Asp Ser Asp Ser Asp Ser Asp Ser Glu Asp Asp Ile
                1970                1975                1980

 Asn Ser Val Met Lys Cys Leu Pro Glu Asn Ser Ala Pro Leu Ile
                1985                1990                1995

 Glu Phe Ala Asn Val
                2000

<210> 2596
<211> 2113
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1838-1860, 2078
<223> Unknown base

<400> 2596
 aacttgatta tattaatttt gggttttttg ttttgttttg ttttgttttt 50

 taatttttca aagaatttgt ggatcttggt ataaagtcat tggaacatat 100

 ctgttttaac agcaagagat cctaggcaga tacttcaaaa ggttaaaaat 150

 tcttaatcct acagaatttt aaatgaatct tatcaatgtt ttgtaaacaa 200

 acaatatgaa tggccaaaaa attgccctcc attttactgg caggtaattt 250

 atattgtctt acttaagaat tctcccctag tttttcaatt gtactttatc 300

 gtgttgtttt caatgagata agtattttca tagggaaagc attttccagc 350

 ataatatttg cttgggtagc atccgggttt tagtatttaa ccaagagcct 400

 tttaaatatt gaaaacccat agttcagaaa atgttagtat tgctgccctt 450

 cttcacataa attttttttt aaattatact attattttgc ttaattttat 500

 attgggttaa aacaaccttc aagaaggtta actaggaaag aagacctttt 550

 tgttttattt ttactattta tatatagaag acaaatcagc atttggtgat 600

 agttttacat gaccagttat caaacggtca tagtatgaag tgtgcagttg 650

 ttcattatta gtaaattatg tttgattttt aaactattta gtactaatag 700

 ttgagatgaa aactgaagaa aaatgccaat gtgacgtttg tgtatagcta 750

 gccttaaaaa acttcccatg tttttaggtg acttttttcc ccctcttagt 800

 actctggaga aacaatgaag atgggccatc tcaattccag atgtaaacaa 850

 aaagtaattt ttatttcaac atttaatgta actgctatta ttgtggattc 900

 ttgtcttgtg tattttcttt cccttattca agtaatatag aataactttc 950

 cttaaaatga tttgatccaa gatacgtcat ttctgtattg gcaaaatgcc 1000

 actattaaag tgtaattctt gaatttaggt tgaattgatg actttttaaa 1050

 acaaaacaaa cactggacag ttctacattg tattgcgttt gcgaatgtgc 1100

 gtgaacacac gcacacgtgc aggagaatgt agtgccataa gaacactggc 1150

 gctttttaaa actttccaag ctagctactt attttcattt tcagggttga 1200

 gtactctaag ctctctactt actgtgagaa gttttctaca ttgtaaaatt 1250

 aaaagattat atttaaaata cttctttagg atgttattca gccatcaaaa 1300

 aaaaacccaa ctaaaatgtc ttaccagtaa agtattatta aaagcctcat 1350

 ttgtggagat tcgctgactt ccttggttaa gctgtcttgt atttacttaa 1400

 tttgtcccct caaccaggtg ttttcttttc agcctgttac tgtcctgtgc 1450

 catttttaaa aatagccatc atgagtaagg gcttctttaa aataatccct 1500

 gacaatatct ttggcattaa tacgacataa agacaagaca gtatatgtat 1550

 gttttcattc ctgttttgta cgagtgcctc attttgtagt catgaaagta 1600

 acatagtacc ttaaataaaa atgtaatgac taatctaagg tctaggaata 1650

 actattgtag aagctaagta gaacacttag tttggggtgt caattttcta 1700

 tcaacgcaaa caccttaggg tacccagacc aattttatgt atatatattc 1750

 tgaaatgctc cctttttaat gtggtcattt gttgccttct aagttgagag 1800

 gacaaaactg aataaagtga atgttaattg tagtctannn nnnnnnnnnn 1850

 nnnnnnnnnn attgcaagat tgctttaaga ttgcagaaat atgcattatt 1900

 agccagcata gataatccag atgttataat aggaaggaaa aacaactcca 1950

 gttaaaatgt gactgtggcg actccctttt atgtatacat ttaaatgcat 2000

 agttgcagag gacacatccc tccccttctg tctccctaac ttgaactgta 2050

 gaccgtcctc actgggaaga ggtagggnca cattttgtgc aatagcaagc 2100

 tatggccact tct 2113

<210> 2597
<211> 43
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 33
<223> unknown amino acid

<220>
<221> Unsure
<222> 1838-1860, 2078
<223> Unknown amino acid

<400> 2597
 Met Tyr Thr Phe Lys Cys Ile Val Ala Glu Asp Thr Ser Leu Pro
   1               5                  10                  15

 Phe Cys Leu Pro Asn Leu Asn Cys Arg Pro Ser Ser Leu Gly Arg
                  20                  25                  30

 Gly Arg Xaa Thr Phe Cys Ala Ile Ala Ser Tyr Gly His
                  35                  40

<210> 2598
<211> 1837
<212> DNA
<213> Homo sapien

<400> 2598
 gagccgcgca cgggactggg aaggggaccc acccgagggt ccagccacca 50

 gccccctcac taatagcggc caccccggca gcggcggcag cagcagcagc 100

 gacgcagcgg cgacagctca gagcagggag gccgcgccac ctgcgggccg 150

 gccggagcgg gcagccccag gccccctccc cgggcacccg cgttcatgca 200

 acgcctggtg gcctgggacc cagcatgtct ccccctgccg ccgccgccgc 250

 ctgcctttaa atccatggaa gtggccaact tctactacga ggcggactgc 300

 ttggctgctg cgtacggcgg caaggcggcc cccgcggcgc cccccgcggc 350

 cagacccggg ccgcgccccc ccgccggcga gctgggcagc atcggcgacc 400

 acgagcgcgc catcgacttc agcccgtacc tggagccgct gggcgcgccg 450

 caggccccgg cgcccgccac ggccacggac accttcgagg cggctccgcc 500

 cgcgcccgcc cccgcgcccg cctcctccgg gcagcaccac gacttcctct 550

 ccgacctctt ctccgacgac tacgggggca agaactgcaa gaagccggcc 600

 gagtacggct acgtgagcct ggggcgcctg ggggccgcca agggcgcgct 650

 gcaccccggc tgcttcgcgc ccctgcaccc accgcccccg ccgccgccgc 700

 cgcccgccga gctcaaggcg gagccgggct tcgagcccgc ggactgcaag 750

 cggaaggagg aggccggggc gccgggcggc ggcgcaggca tggcggcggg 800

 cttcccgtac gcgctgcgcg cttacctcgg ctaccaggcg gtgccgagcg 850

 gcagcagcgg gagcctctcc acgtcctcct cgtccagccc gcccggcacg 900

 ccgagccccg ctgacgccaa ggcgcccccg accgcctgct acgcgggggc 950

 cgcgccggcg ccctcgcagg tcaagagcaa ggccaagaag accgtggaca 1000

 agcacagcga cgagtacaag atccggcgcg agcgcaacaa catcgccgtg 1050

 cgcaagagcc gcgacaaggc caagatgcgc aacctggaga cgcagcacaa 1100

 ggtcctggag ctcacggccg agaacgagcg gctgcagaag aaggtggagc 1150

 agctgtcgcg cgagctcagc accctgcgga acttgttcaa gcagctgccc 1200

 gagcccctgc tcgcctcctc cggccactgc tagcgcggcc cccgcgcgcg 1250

 tccccctgcc ggccggggct gagactccgg ggagcgcccg cgcccgcgcc 1300

 ctcgcccccg cccccggcgg cgccggcaaa actttggcac tggggcactt 1350

 ggcagcgcgg ggagcccgtc ggtaatttta atattttatt atatatatat 1400

 atctatattt ttgtccaaac caaccgcaca tgcagatggg gctcccgccc 1450

 gtggtgttat ttaaagaaga aacgtctatg tgtacagatg aatgataaac 1500

 tctctgcttc tccctctgcc cctctccagg cgccggcggg cgggccggtt 1550

 tcgaagttga tgcaatcggt ttaaacatgg ctgaacgcgt gtgtacacgg 1600

 gactgacgca acccacgtgt aactgtcagc cgggccctga gtaatcgctt 1650

 aaagatgttc ctacgggctt gttgctgttg atgttttgtt ttgttttgtt 1700

 ttttggtctt tttttgtatt ataaaaaata atctatttct atgagaaaag 1750

 aggcgtctgt atattttggg aatcttttcc gtttcaagca ttaagaacac 1800

 ttttaataaa cttttttttg agaatggtta caaagcc 1837

<210> 2599
<211> 345
<212> PRT
<213> Homo sapien

<400> 2599
 Met Gln Arg Leu Val Ala Trp Asp Pro Ala Cys Leu Pro Leu Pro
   1               5                  10                  15

 Pro Pro Pro Pro Ala Phe Lys Ser Met Glu Val Ala Asn Phe Tyr
                  20                  25                  30

 Tyr Glu Ala Asp Cys Leu Ala Ala Ala Tyr Gly Gly Lys Ala Ala
                  35                  40                  45

 Pro Ala Ala Pro Pro Ala Ala Arg Pro Gly Pro Arg Pro Pro Ala
                  50                  55                  60

 Gly Glu Leu Gly Ser Ile Gly Asp His Glu Arg Ala Ile Asp Phe
                  65                  70                  75

 Ser Pro Tyr Leu Glu Pro Leu Gly Ala Pro Gln Ala Pro Ala Pro
                  80                  85                  90

 Ala Thr Ala Thr Asp Thr Phe Glu Ala Ala Pro Pro Ala Pro Ala
                  95                 100                 105

 Pro Ala Pro Ala Ser Ser Gly Gln His His Asp Phe Leu Ser Asp
                 110                 115                 120

 Leu Phe Ser Asp Asp Tyr Gly Gly Lys Asn Cys Lys Lys Pro Ala
                 125                 130                 135

 Glu Tyr Gly Tyr Val Ser Leu Gly Arg Leu Gly Ala Ala Lys Gly
                 140                 145                 150

 Ala Leu His Pro Gly Cys Phe Ala Pro Leu His Pro Pro Pro Pro
                 155                 160                 165

 Pro Pro Pro Pro Pro Ala Glu Leu Lys Ala Glu Pro Gly Phe Glu
                 170                 175                 180

 Pro Ala Asp Cys Lys Arg Lys Glu Glu Ala Gly Ala Pro Gly Gly
                 185                 190                 195

 Gly Ala Gly Met Ala Ala Gly Phe Pro Tyr Ala Leu Arg Ala Tyr
                 200                 205                 210

 Leu Gly Tyr Gln Ala Val Pro Ser Gly Ser Ser Gly Ser Leu Ser
                 215                 220                 225

 Thr Ser Ser Ser Ser Ser Pro Pro Gly Thr Pro Ser Pro Ala Asp
                 230                 235                 240

 Ala Lys Ala Pro Pro Thr Ala Cys Tyr Ala Gly Ala Ala Pro Ala
                 245                 250                 255

 Pro Ser Gln Val Lys Ser Lys Ala Lys Lys Thr Val Asp Lys His
                 260                 265                 270

 Ser Asp Glu Tyr Lys Ile Arg Arg Glu Arg Asn Asn Ile Ala Val
                 275                 280                 285

 Arg Lys Ser Arg Asp Lys Ala Lys Met Arg Asn Leu Glu Thr Gln
                 290                 295                 300

 His Lys Val Leu Glu Leu Thr Ala Glu Asn Glu Arg Leu Gln Lys
                 305                 310                 315

 Lys Val Glu Gln Leu Ser Arg Glu Leu Ser Thr Leu Arg Asn Leu
                 320                 325                 330

 Phe Lys Gln Leu Pro Glu Pro Leu Leu Ala Ser Ser Gly His Cys
                 335                 340                 345

<210> 2600
<211> 3614
<212> DNA
<213> Homo sapien

<400> 2600
 agcggagttg cgggcgcgtg gctgctgagg ttggcggcgg tgccgcgcgc 50

 ccgacgggcc ggtggttgcg gggcctcccg cctcgacccg ggctgggggc 100

 agccgtggcg gccgccgggg accgcaaggg gcggaggaaa ggagggggcc 150

 ggtcccggca cgcagaggag cagccgacca tgccccgaga caacatggcc 200

 tccttgatcc aacggatcgc ccgccaggct tgcctcacct tccggggcag 250

 ctggggcggc cgcggcgctt ccgatcgcga cgcggcttct ggcgcggagg 300

 cgccgatgca gccgggcttc cccgagaacc tgagcaagct gaagagcctc 350

 ctgacccagc tccgcgccga ggacttgaac atcgccccgc gcaaggccac 400

 actgcagccg ctgccgccca acctgccgcc agtcacctac atgcacatct 450

 acgagacgga cggcttcagc ctgggcgtgt tcctgctcaa gagcggcacg 500

 tccatcccgc tgcacgacca cccgggcatg cacggcatgc tcaaggtgct 550

 gtacggcacc gtgcgcatca gctgcatgga caagctagac gcgggcggcg 600

 ggcaacggcc gcgggccttg ccgcccgagc agcagttcga gccgccgctg 650

 cagccccggg agcgagaagc cgtgcggccg ggcgtgctgc gttcgcgggc 700

 cgagtacacc gaggccagcg gcccctgcat cctcacaccg caccgggaca 750

 acctgcacca gatcgacgcc gtggaagggc ctgccgcctt cctggacatc 800

 ctggccccgc cctacgaccc ggacgatggc cgggactgcc actattaccg 850

 ggtgctggag ccggtcaggc ccaaggaggc ctccagctcg gcctgtgacc 900

 tgcctcgaga ggtgtggctc ctggagaccc cacaggccga tgacttctgg 950

 tgcgagggag aaccctatcc aggtcccaag gtcttccctt gaagccactg 1000

 gcgcccagga gcggtgggcc gaagacgtgc cctaccctac cacaagggct 1050

 gtgtctctac cccctagcct gggcgttgga tctactggaa tgagcagcag 1100

 ccgcttcctc ggcagccttg ggaagcacgg gcgactggac agcagccgcc 1150

 gggcacggtt atgggggcgg ggtgggcggg gaggctagat tgtttcctgg 1200

 tactgtcact gccactgggg ctttgatttg gaggaatggg gcaggggact 1250

 atctgaagcg cttccatcct aaagccataa tgaaaatatc ttcctctctt 1300

 ccccattcta tacaaaatac taagtggttt tcttgctccc actccctacc 1350

 ccttagttaa atagggttta ttttccactc atgcccttat gccttttttt 1400

 cttatagttt tttaacttat tgactgtgca tgacccagtg gtttgaattg 1450

 tttttagttc aagtcattgg taaaaactag gtttaaggag atgagctact 1500

 gtttaaagtg agctggcctg cctaattaat tccttgtgaa aactaaatga 1550

 ttttttcagt ttggggatca ttctcacaac ataactatgc atgtagagga 1600

 cgagatttat tttctttcct ccctttgccc agtagccaca tctggtttac 1650

 tcaggcagca tctactaaga aattcagcac ctgcatatct ctgtgacatg 1700

 gtcacttaga gcttatcttc cctatgaatc tccagatctg tgagtcgagc 1750

 agatttcatg ttgcagattc acctttaatg caaagactgt attatcctca 1800

 catgactttt tttcttgtct tactgtacct taaaaggtga tagagtaatt 1850

 ctgtattttc taacgggaag attcaaagga gctgaatgtg ttatgcttcc 1900

 aaacaactga atgtaaaaca ctcctagcca gttgttgcat tccctatatt 1950

 tatttacttc caatatttta ctgtaaaagt agggagaaat attatgttga 2000

 tagttgtttc atattctctc aggaacttta atgttcccga ctcgggtgat 2050

 tccagctgtg ttgctggcag tgttgtctca accctctccc taaaatgact 2100

 gagccctggg ttcatctaat gtggttttcc ttaggaagag atagaaggca 2150

 cagaagatca cagctagaga attgagaatt aactatacta ctagccattt 2200

 tagggcacca aaacttggga ttaaacactt cctacttccc actcccaact 2250

 cctgaaatga agtcttgcta tctgtgacta gttttatttt tgtgctttta 2300

 atagtccgag cagtcttacc ttgtttacac atgtattgac accatttgct 2350

 tcaggccatg gagcactgtt tctccctttt tactatttat aggattccgt 2400

 tttttcacaa gacttttaat aaaaagaaat tgtagaaata aacacattaa 2450

 aatttgccca gctgtcgtct aagccctctt gattgacttg cccaagtggc 2500

 aatagagttc taatatctat aataaaggga gatttgctat tattagtgga 2550

 atgttgaccc cgtatgtaga gaaacagtac gtgcctttgc ctctttatgc 2600

 acacagagac ccagggtgag ggagtatttg ttcccagttt ttaagatagt 2650

 ataaaaaagc aaatacttgg tgagtgattt aaaaataaaa ccaaaacaaa 2700

 acacaaaaag atattccaca ggacatgcca ctttattata aaacctgaca 2750

 caggcatagt accaagtatt tcctgcattg ttgctaaaat tgttttattg 2800

 tagctccaca ttctggtgta gtttaaaatg cctttggggg cagtttgaag 2850

 cagttcttca tgccacttag tttgaaaata aaattctaga tatgcaaatg 2900

 attttcttag aaaacttcac aaaataaaag atcttgtttt tttttccata 2950

 gcacagtaat gaatgtggtt atcaatcaca tacttttttg gattatattg 3000

 tagcaaaaag ttgattagct taccaagatt attaatagca atgtatgtgt 3050

 tataatacaa cttagtacat taaagctacg aaaactcatc ctggctgtag 3100

 gatagtaata aaggaagaat tatgacttca ttatgaaaaa aagaagtttt 3150

 aaagttttca attacgagca atttggaaga aaaaacctaa ggtgcttttc 3200

 aaaagagtaa ctgaaattgt tgcaggccaa aacagcaata tgatatctca 3250

 gatttagttc aataagaaca gtgaaacttt tggttcacta ataaattctg 3300

 agtaaattag tggtgaagac aaaatataac ttgttttagt gagccactga 3350

 ggaaagaata tgcttattac aaagacaaaa tgtggtgcag aaactatctt 3400

 gcacctgtgt gcataaactg ttagtcgtga ctgacttggt gtgttgctat 3450

 tgtgtttcta tatactccgt ccaatataga taatgtttta ataacaactg 3500

 tgggataaaa gttatcttcc ccttggaaag actaatgagc acaatgatat 3550

 taatcacttt tatggtgaat aataaatgca ataattgcct catgggtgaa 3600

 aaaaaaaaaa aaaa 3614

<210> 2601
<211> 228
<212> PRT
<213> Homo sapien

<400> 2601
 Met Gln Pro Gly Phe Pro Glu Asn Leu Ser Lys Leu Lys Ser Leu
   1               5                  10                  15

 Leu Thr Gln Leu Arg Ala Glu Asp Leu Asn Ile Ala Pro Arg Lys
                  20                  25                  30

 Ala Thr Leu Gln Pro Leu Pro Pro Asn Leu Pro Pro Val Thr Tyr
                  35                  40                  45

 Met His Ile Tyr Glu Thr Asp Gly Phe Ser Leu Gly Val Phe Leu
                  50                  55                  60

 Leu Lys Ser Gly Thr Ser Ile Pro Leu His Asp His Pro Gly Met
                  65                  70                  75

 His Gly Met Leu Lys Val Leu Tyr Gly Thr Val Arg Ile Ser Cys
                  80                  85                  90

 Met Asp Lys Leu Asp Ala Gly Gly Gly Gln Arg Pro Arg Ala Leu
                  95                 100                 105

 Pro Pro Glu Gln Gln Phe Glu Pro Pro Leu Gln Pro Arg Glu Arg
                 110                 115                 120

 Glu Ala Val Arg Pro Gly Val Leu Arg Ser Arg Ala Glu Tyr Thr
                 125                 130                 135

 Glu Ala Ser Gly Pro Cys Ile Leu Thr Pro His Arg Asp Asn Leu
                 140                 145                 150

 His Gln Ile Asp Ala Val Glu Gly Pro Ala Ala Phe Leu Asp Ile
                 155                 160                 165

 Leu Ala Pro Pro Tyr Asp Pro Asp Asp Gly Arg Asp Cys His Tyr
                 170                 175                 180

 Tyr Arg Val Leu Glu Pro Val Arg Pro Lys Glu Ala Ser Ser Ser
                 185                 190                 195

 Ala Cys Asp Leu Pro Arg Glu Val Trp Leu Leu Glu Thr Pro Gln
                 200                 205                 210

 Ala Asp Asp Phe Trp Cys Glu Gly Glu Pro Tyr Pro Gly Pro Lys
                 215                 220                 225

 Val Phe Pro


<210> 2602
<211> 2935
<212> DNA
<213> Homo sapien

<400> 2602
 ttaaatgttt tgcttcatgc aaaatcttgt aattttagat gtgcttagtt 50

 ttttaaagat tatctgcata taaaattaag gtaaaagata agcaaagatt 100

 tctgtaatga agcatatttt cagttcagtg tgagttgctc atttgttaat 150

 tttgtcagta ggatgatttt gttagggaaa acgcaatcac tgcgaaaaat 200

 gtgatataga aaacattttg cttgaaggat tggctttgtt tttgtgtggg 250

 gaatttagtg cattttccat tctattagtc atcatatatt aaatagtcgt 300

 aaatgtagag ttattaaata attgagcttt tttccatttt aggtttactc 350

 aggattcact ccttctccag ttgcacagcc acacccttca gctggcctta 400

 atgttgactt tgaatctgtg tttggaaata aatctacaaa tgttattgta 450

 gattctgggg gtggacttct caaaccaaca gtggcctctc agaaccagaa 500

 ccttcctgtt gccaaactcc cacctagcaa gttagtatct gatgacttgg 550

 attcatcttt agccaacctt gtgggcaatc ttggcatcgg aaatggaacc 600

 actaagaatg atgtaaattg gagtcaacca ggtgaaaaga agttaactgg 650

 gggatctaac tggcaaccaa aggttgcacc aacaaccgct tggaatgctg 700

 caacaatgaa tggcatgcat tttccacaat acgcaccccc tgtaatggcc 750

 tatcctgcta ctacaccaac aggcatgata ggatatggaa ttcctccaca 800

 aatgggaagt gttcctgtaa tgacgcaacc aaccttaata tacagccagc 850

 ctgtcatgag acctccaaac ccctttggcc ctgtatcagg agcacagata 900

 cagtttatgt aacttgatgg aagaaaatgg aattactcca aaaagacaag 950

 tgctcaagca gcaaaatcct tacttccagc aaaatccaaa ctgctgtctc 1000

 ttaaatctct taaactctct tcttccatta gaatgctaca agtaactcag 1050

 tgaaggccca tgaaggaaat tgggactagt ttataggaga acgtatcaat 1100

 acagtttata aagccaagaa ttgctatgat ttaagactaa gatctgtctt 1150

 tttggtgact aacccttcaa ttctttcaac tcctgttaat acccataatc 1200

 agtaacctat caagaaaagc ccttatttgg aaagtgtgaa atttgtattt 1250

 ggaaaagctg cctggagaga agaactgtgt cctttactgt atttcaacag 1300

 gactcttttg ggggatcaaa attaaaattc ctaattatgc attatctttc 1350

 ttttctccag tcctcacaaa tacagaaaca ataactgaaa ttaacttttc 1400

 tttttttaaa aaaaattata ttcagtttgc agtagacatt ccttaagtat 1450

 ttgtatttat ttatgattat caattttaca taacattaat attgtatcag 1500

 acctccttat gaaaatgagt atggatgtgc acagtatgtt tgatttttat 1550

 ccacaagaat gaatctgatt cagaatgctt ttctcagctg acatacagag 1600

 cactaaatat tttaaggcaa gtccataggt ctgaatctct taagaattct 1650

 cggcctctgt gggatttagg gaagcattat aaatgcatta atccttatag 1700

 tcaattctgt gcctaggatt ttgccaggga acagttcact gactaggaaa 1750

 agcactacat tttaaattca gcattagtgc attgggaagg atctttactg 1800

 ctttgtgctt ggcatgtcat tattttccat ttgacattag ggcctttcca 1850

 aaatgaatgt gaggaattgc tttcacttca agactttcct tcttttcact 1900

 aaaactctag aaggtgttac aagggggagg gaaggggggc aaagtccttg 1950

 aacattttct ttggctcgtg ccatgttatg atcatatacc ttttaaataa 2000

 ggggaaatag tatctttaaa gttaatgtct agccaagagt ttagtaaacg 2050

 aagaattaaa ctgcactgtt gatcggtgct ttgtgtaaat acatctttaa 2100

 catttgggtg gagaggggcc ttaagaagga cagttcattg taggaaagca 2150

 attctgtaca tgagtttaag cattcttgtt gcattgtctc tgcagattct 2200

 atttttgttt acaatattaa aatgtatgtt agcaaaatgg gtggattttc 2250

 aaataaaatg cagcttccac aaaagttttg ttatggtatt ctggtctgag 2300

 atgcattttc atttttcctt tctcttttta ttatcaatat tgtcattttt 2350

 ccctaataaa atatacccag gtgattatat ttgttgatct aataacatgg 2400

 aaggtttgtt ttatatgaat tttcaaaaag atgtctcttt acactttttg 2450

 ttaccttgta gactcttatt gataaatgca actacttatt aaaattgttc 2500

 actttttgtc ttttgatcag atgcctttag tcaggtaagt ttaagggaaa 2550

 atacgcagtt taatgttttg gtacatataa ttatgtctgc caaagaaacc 2600

 tttgattgta tcatattgcc tatttagtag tgcatagggt tcagagtaca 2650

 tgataaagga tcaaaagctt tgcattgata agtgtctcat aatatttgct 2700

 gtgattggag aaaaaatgta gtcgtagcca ataaatttta tcagctttta 2750

 agtttcagta ttattaaacc attttcatat aaactgggaa gttgtacttt 2800

 tataagttac cctccttaac tttacaaatt tttgtctctt gtggtgtttg 2850

 aggaggtgtt tatatttaag gtctgtggct tgttttcttt catattgcct 2900

 tttttttttt aagtatgttt cagtatgcat agcgg 2935

<210> 2603
<211> 15
<212> PRT
<213> Homo sapien

<400> 2603
 Leu Asn Val Leu Leu His Ala Lys Ser Cys Asn Phe Arg Cys Ala
   1               5                  10                  15

<210> 2604
<211> 3880
<212> DNA
<213> Homo sapien

<400> 2604
 gctcgccgcc gcccgcccag gcggcgatga cacggcgccc gcggcggccc 50

 ggaggcgccg ggtgggccgt ttgctgaccg gatcgcggct acccgccagc 100

 gtgtccgcgg cgccgccgcc agcatgggct gtgccccgag catccacatt 150

 tccgagcgcc tggtggccga ggacgcgcct agccccgcgg caccgccgct 200

 gtcgtccggc gggccgcgcc tcccgcaggg ccagaagacg gccgccttgc 250

 cccggacccg cggcgccggc ctcttggagt cggagcttcg cgacggcagc 300

 ggcaagaagg tagcagtagc tgatgtgcag tttggcccca tgagatttca 350

 tcaagatcaa cttcaggtac ttttagtgtt taccaaagaa gataaccaat 400

 gtaatggatt ctgcagggca tgtgaaaaag cagggtttaa gtgtacagtt 450

 accaaggagg ctcaggctgt ccttgcctgt ttcctggaca aacatcatga 500

 cattatcatc atagaccaca gaaatcctcg acagctggat gcagaggcac 550

 tgtgcaggtc tatcagatca tcaaaactct cagaaaacac agttattgtt 600

 ggtgtagtac gcagggtgga tagagaagag ttgtccgtaa tgcctttcat 650

 ttctgctgga tttacaagga ggtatgtaga aaaccccaac atcatggcct 700

 gctacaatga actgctccag ctggagtttg gagaggtgcg atcacaactg 750

 aaactcaggg cttgtaacag tattcactgc attagaaaac agtgaagatg 800

 caattgaaat tacaagcgaa gaccgtttta tacagtatgc aaatcctgca 850

 tttgaaacaa caatgggcta tcagtcaggt gaattaatag ggaaggagtt 900

 aggagaagtg cctataaatg aaaaaaaggc tgacttgctc gatactataa 950

 attcatgcat caggataggc aaggagtggc aaggaattta ctatgccaaa 1000

 aagaaaaacg gagataatat acaacaaaat gtgaagataa tacctgtcat 1050

 tggacaggga ggaaaaatta gacactatgt gtccattatc agagtgtgca 1100

 atggcaacaa taaggctgag aaaatatccg aatgtgttca gtctgacact 1150

 catacagata atcagacagg caaacataaa gacaggagaa aaggctcact 1200

 agacgtcaaa gctgttgcct cccgtgcaac tgaagtttcc agccagagac 1250

 gacactcttc catggcccgg atacattcca tgacaattga ggcgcccatc 1300

 accaaggtaa tcaatattat caatgctgcc caggaaagta gtcccatgcc 1350

 tgtgacagaa gccctagacc gtgtgctgga aattctaaga accactgagt 1400

 tatattcacc acagtttggt gctaaagatg atgatcccca tgccaatgac 1450

 cttgttgggg gcttaatgtc tgatggtttg cgaagactat cagggaatga 1500

 atatgttctt tcaacaaaaa acactcaaat ggtttcaagc aatataatca 1550

 ctcccatctc ccttgatgat gtcccgccac ggatagctcg ggccatggaa 1600

 aatgaggaat actgggactt tgatattttt gaactggagg ctgccaccca 1650

 caataggcct ttgatttatc ttggtctcaa aatgtttgct cgctttggaa 1700

 tctgtgaatt cttacactgc tccgagtcaa cgctaagatc atggttacaa 1750

 attatcgaag ccaattatca ttcctccaat ccctaccaca attctacaca 1800

 ttctgctgat gtgcttcatg ccactgccta ttttctctcc aaggagagga 1850

 taaaggaaac tttagatcca attgatgagg tcgctgcact catcgcagcc 1900

 accattcatg atgtggatca ccctgggaga accaactcct tcctgtgtaa 1950

 tgctggaagt gagctggcca ttttgtacaa tgacactgct gtgctggaga 2000

 gccaccatgc ggccttggcc ttccagctga ccactggaga tgataaatgc 2050

 aatatattta aaaacatgga gaggaatgat tatcggacac tgcgccaggg 2100

 gattatcgac atggtcttag ccacagaaat gacaaagcac tttgagcatg 2150

 tcaacaaatt tgtcaacagc atcaacaaac ccttggcaac actagaagaa 2200

 aatggggaaa ctgataaaaa ccaggaagtg ataaacacta tgcttaggac 2250

 tccagagaac cggaccctaa tcaaacgaat gctgattaaa tgtgctgatg 2300

 tgtccaatcc ctgccgaccc ctgcagtact gcatcgagtg ggctgcacgc 2350

 atttcggaag aatatttttc tcagactgat gaagagaagc agcagggctt 2400

 acctgtggtg atgccagtgt ttgacagaaa tacctgcagc atccccaaat 2450

 cccaaatctc tttcattgat tacttcatca cagacatgtt tgatgcttgg 2500

 gatgcctttg tagacctgcc tgatttaatg cagcatcttg acaacaactt 2550

 taaatactgg aaaggactgg acgaaatgaa gctgcggaac ctccgaccac 2600

 ctcctgaata gtgggagaca ccacccagag ccctgaagct ttgttccttc 2650

 ggtcatttgg aattcctgag ggcagccaga gctccttggt cctttcagta 2700

 ctaggcagaa cagcccccga tctgcatagc ctgtgaaagc ccacggggac 2750

 atcagtaacc ttctgcagcc accatccaat gccattactg tcaagtgaga 2800

 cttggccact gtagcctggg cctgctgcag gagctcttca gaaaggcaca 2850

 tgaggaccac ggtttgcctc agtttctggt aaaacacaag gtctggagtg 2900

 cccctgcaaa gggtattgat ggacttcctg ccagtgacag agcatgtcta 2950

 ttgcaaacaa ttctctcagt tacgttcagc acttaagaac ggctaatggc 3000

 aataggatct ttagcaactt tttcacatca tagaaggtgc aatcgctcac 3050

 ttgggaacac tactgagagt gacttctctt ttaaaattga gtagcagatg 3100

 aaaaattaaa atttgaactt gattattaat atcaattaaa atgttttatt 3150

 tattttatta aaagctcaat attttctatg aattcaaaaa tacttcagag 3200

 ccaaagccaa cttcaaatac cgtgaccaaa tttacatgat tcatattcat 3250

 tatgcattac ttggtataca gacttatttt cataatgcaa attaataaaa 3300

 tgacactttt actgcactat agaaatattc atgtatgtta aacttttctg 3350

 attgaggcta actggaaaaa gctggggtcg tattctaagt gctaaagaag 3400

 gctgcttcta ctgtatagaa cccagggctc tgaaacagct ctagccgcct 3450

 aatgcacttc acaggtaact ccccaaggta aaactagact ctcttgttgg 3500

 ttcgcaaaga aaagttagga cttaacactt ttttctaaaa ttttataatt 3550

 caatttccaa aagtctactc tattttatac tgtttctaca aaatattcct 3600

 tataaaaaca aagaacaaaa attgaatatt taatgaattg acattttata 3650

 accaacctgt ttttatctac ggtgggaatc tttgatgcca gaaatttata 3700

 aagaggttct gtatcttcac accttgaata agcataatac cataaaaaat 3750

 gacacttgac atgtcaatgt atttgtcatt tcattttaaa ctcgtatttg 3800

 tggttttttt cccagataaa aatgaaatta aaccatttct ttttaagaaa 3850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3880

<210> 2605
<211> 828
<212> PRT
<213> Homo sapien

<400> 2605
 Met Gly Cys Ala Pro Ser Ile His Ile Ser Glu Arg Leu Val Ala
   1               5                  10                  15

 Glu Asp Ala Pro Ser Pro Ala Ala Pro Pro Leu Ser Ser Gly Gly
                  20                  25                  30

 Pro Arg Leu Pro Gln Gly Gln Lys Thr Ala Ala Leu Pro Arg Thr
                  35                  40                  45

 Arg Gly Ala Gly Leu Leu Glu Ser Glu Leu Arg Asp Gly Ser Gly
                  50                  55                  60

 Lys Lys Val Ala Val Ala Asp Val Gln Phe Gly Pro Met Arg Phe
                  65                  70                  75

 His Gln Asp Gln Leu Gln Val Leu Leu Val Phe Thr Lys Glu Asp
                  80                  85                  90

 Asn Gln Cys Asn Gly Phe Cys Arg Ala Cys Glu Lys Ala Gly Phe
                  95                 100                 105

 Lys Cys Thr Val Thr Lys Glu Ala Gln Ala Val Leu Ala Cys Phe
                 110                 115                 120

 Leu Asp Lys His His Asp Ile Ile Ile Ile Asp His Arg Asn Pro
                 125                 130                 135

 Arg Gln Leu Asp Ala Glu Ala Leu Cys Arg Ser Ile Arg Ser Ser
                 140                 145                 150

 Lys Leu Ser Glu Asn Thr Val Ile Val Gly Val Val Arg Arg Val
                 155                 160                 165

 Asp Arg Glu Glu Leu Ser Val Met Pro Phe Ile Ser Ala Gly Phe
                 170                 175                 180

 Thr Arg Arg Tyr Val Glu Asn Pro Asn Ile Met Ala Cys Tyr Asn
                 185                 190                 195

 Glu Leu Leu Gln Leu Glu Phe Gly Glu Val Arg Ser Gln Leu Lys
                 200                 205                 210

 Leu Arg Ala Cys Asn Ser Ile His Cys Ile Arg Lys Gln Glu Asp
                 215                 220                 225

 Ala Ile Glu Ile Thr Ser Glu Asp Arg Phe Ile Gln Tyr Ala Asn
                 230                 235                 240

 Pro Ala Phe Glu Thr Thr Met Gly Tyr Gln Ser Gly Glu Leu Ile
                 245                 250                 255

 Gly Lys Glu Leu Gly Glu Val Pro Ile Asn Glu Lys Lys Ala Asp
                 260                 265                 270

 Leu Leu Asp Thr Ile Asn Ser Cys Ile Arg Ile Gly Lys Glu Trp
                 275                 280                 285

 Gln Gly Ile Tyr Tyr Ala Lys Lys Lys Asn Gly Asp Asn Ile Gln
                 290                 295                 300

 Gln Asn Val Lys Ile Ile Pro Val Ile Gly Gln Gly Gly Lys Ile
                 305                 310                 315

 Arg His Tyr Val Ser Ile Ile Arg Val Cys Asn Gly Asn Asn Lys
                 320                 325                 330

 Ala Glu Lys Ile Ser Glu Cys Val Gln Ser Asp Thr His Thr Asp
                 335                 340                 345

 Asn Gln Thr Gly Lys His Lys Asp Arg Arg Lys Gly Ser Leu Asp
                 350                 355                 360

 Val Lys Ala Val Ala Ser Arg Ala Thr Glu Val Ser Ser Gln Arg
                 365                 370                 375

 Arg His Ser Ser Met Ala Arg Ile His Ser Met Thr Ile Glu Ala
                 380                 385                 390

 Pro Ile Thr Lys Val Ile Asn Ile Ile Asn Ala Ala Gln Glu Ser
                 395                 400                 405

 Ser Pro Met Pro Val Thr Glu Ala Leu Asp Arg Val Leu Glu Ile
                 410                 415                 420

 Leu Arg Thr Thr Glu Leu Tyr Ser Pro Gln Phe Gly Ala Lys Asp
                 425                 430                 435

 Asp Asp Pro His Ala Asn Asp Leu Val Gly Gly Leu Met Ser Asp
                 440                 445                 450

 Gly Leu Arg Arg Leu Ser Gly Asn Glu Tyr Val Leu Ser Thr Lys
                 455                 460                 465

 Asn Thr Gln Met Val Ser Ser Asn Ile Ile Thr Pro Ile Ser Leu
                 470                 475                 480

 Asp Asp Val Pro Pro Arg Ile Ala Arg Ala Met Glu Asn Glu Glu
                 485                 490                 495

 Tyr Trp Asp Phe Asp Ile Phe Glu Leu Glu Ala Ala Thr His Asn
                 500                 505                 510

 Arg Pro Leu Ile Tyr Leu Gly Leu Lys Met Phe Ala Arg Phe Gly
                 515                 520                 525

 Ile Cys Glu Phe Leu His Cys Ser Glu Ser Thr Leu Arg Ser Trp
                 530                 535                 540

 Leu Gln Ile Ile Glu Ala Asn Tyr His Ser Ser Asn Pro Tyr His
                 545                 550                 555

 Asn Ser Thr His Ser Ala Asp Val Leu His Ala Thr Ala Tyr Phe
                 560                 565                 570

 Leu Ser Lys Glu Arg Ile Lys Glu Thr Leu Asp Pro Ile Asp Glu
                 575                 580                 585

 Val Ala Ala Leu Ile Ala Ala Thr Ile His Asp Val Asp His Pro
                 590                 595                 600

 Gly Arg Thr Asn Ser Phe Leu Cys Asn Ala Gly Ser Glu Leu Ala
                 605                 610                 615

 Ile Leu Tyr Asn Asp Thr Ala Val Leu Glu Ser His His Ala Ala
                 620                 625                 630

 Leu Ala Phe Gln Leu Thr Thr Gly Asp Asp Lys Cys Asn Ile Phe
                 635                 640                 645

 Lys Asn Met Glu Arg Asn Asp Tyr Arg Thr Leu Arg Gln Gly Ile
                 650                 655                 660

 Ile Asp Met Val Leu Ala Thr Glu Met Thr Lys His Phe Glu His
                 665                 670                 675

 Val Asn Lys Phe Val Asn Ser Ile Asn Lys Pro Leu Ala Thr Leu
                 680                 685                 690

 Glu Glu Asn Gly Glu Thr Asp Lys Asn Gln Glu Val Ile Asn Thr
                 695                 700                 705

 Met Leu Arg Thr Pro Glu Asn Arg Thr Leu Ile Lys Arg Met Leu
                 710                 715                 720

 Ile Lys Cys Ala Asp Val Ser Asn Pro Cys Arg Pro Leu Gln Tyr
                 725                 730                 735

 Cys Ile Glu Trp Ala Ala Arg Ile Ser Glu Glu Tyr Phe Ser Gln
                 740                 745                 750

 Thr Asp Glu Glu Lys Gln Gln Gly Leu Pro Val Val Met Pro Val
                 755                 760                 765

 Phe Asp Arg Asn Thr Cys Ser Ile Pro Lys Ser Gln Ile Ser Phe
                 770                 775                 780

 Ile Asp Tyr Phe Ile Thr Asp Met Phe Asp Ala Trp Asp Ala Phe
                 785                 790                 795

 Val Asp Leu Pro Asp Leu Met Gln His Leu Asp Asn Asn Phe Lys
                 800                 805                 810

 Tyr Trp Lys Gly Leu Asp Glu Met Lys Leu Arg Asn Leu Arg Pro
                 815                 820                 825

 Pro Pro Glu


<210> 2606
<211> 921
<212> DNA
<213> Homo sapien

<400> 2606
 ccggtagcgg gtgtgggggc gcgagcagcg cagggcggcc tctcccccac 50

 ccctcagccc gggcccgggc tcggtccccc ctctccctcc gcttcgcact 100

 cccgtcgggt acgggaaggt ccaagccgct gccgggtgcc cgagggccgt 150

 cgtggccgcc gtcgccacgg gtcccaatgg agccgccgaa tctctatccg 200

 gtgaagctct acgtgtacga cctgtccaaa ggcctggccc ggcggctcag 250

 ccccatcatg ctggggaaac aactggaagg catctggcac acatccatag 300

 ttgtgcacaa ggatgagttc ttcttcggca gtggtggtat ctccagctgc 350

 cccccgggag ggacattgct tgggcctcca gactctgtgg ttgatgtggg 400

 gagtacagaa gtcacagaag aaatctttct ggagtacctc tcctccctgg 450

 gggagtccct gttccgaggt gaggcctaca acctctttga acacaattgt 500

 aacaccttca gcaacgaagt ggcacagttc ctgactgggc ggaagattcc 550

 ttcttacatc acagacctgc cctctgaagt tctctccacg ccctttggac 600

 aggcacttcg gcccctcctg gactccattc agatccagcc tccaggaggg 650

 agctccgtgg gcagacccaa cggccagagc taacaggact gcctgggacc 700

 gccctgcctc accagggctt ttccttttta aacaaaacaa accctaccag 750

 atttctattt tataatttta catcagagct aacaaccagg ggacggcttt 800

 ttaaatttcc cagggaagga gaccgtcagg ccgcatgtag acaatgctgc 850

 taagaaacag aacaaaatgc caccccttct aatagtatta tactaattta 900

 ttaaaaaaaa aaaaaaaaaa a 921

<210> 2607
<211> 226
<212> PRT
<213> Homo sapien

<400> 2607
 Gly Ser Gly Cys Gly Gly Ala Ser Ser Ala Gly Arg Pro Leu Pro
   1               5                  10                  15

 His Pro Ser Ala Arg Ala Arg Ala Arg Ser Pro Leu Ser Leu Arg
                  20                  25                  30

 Phe Ala Leu Pro Ser Gly Thr Gly Arg Ser Lys Pro Leu Pro Gly
                  35                  40                  45

 Ala Arg Gly Pro Ser Trp Pro Pro Ser Pro Arg Val Pro Met Glu
                  50                  55                  60

 Pro Pro Asn Leu Tyr Pro Val Lys Leu Tyr Val Tyr Asp Leu Ser
                  65                  70                  75

 Lys Gly Leu Ala Arg Arg Leu Ser Pro Ile Met Leu Gly Lys Gln
                  80                  85                  90

 Leu Glu Gly Ile Trp His Thr Ser Ile Val Val His Lys Asp Glu
                  95                 100                 105

 Phe Phe Phe Gly Ser Gly Gly Ile Ser Ser Cys Pro Pro Gly Gly
                 110                 115                 120

 Thr Leu Leu Gly Pro Pro Asp Ser Val Val Asp Val Gly Ser Thr
                 125                 130                 135

 Glu Val Thr Glu Glu Ile Phe Leu Glu Tyr Leu Ser Ser Leu Gly
                 140                 145                 150

 Glu Ser Leu Phe Arg Gly Glu Ala Tyr Asn Leu Phe Glu His Asn
                 155                 160                 165

 Cys Asn Thr Phe Ser Asn Glu Val Ala Gln Phe Leu Thr Gly Arg
                 170                 175                 180

 Lys Ile Pro Ser Tyr Ile Thr Asp Leu Pro Ser Glu Val Leu Ser
                 185                 190                 195

 Thr Pro Phe Gly Gln Ala Leu Arg Pro Leu Leu Asp Ser Ile Gln
                 200                 205                 210

 Ile Gln Pro Pro Gly Gly Ser Ser Val Gly Arg Pro Asn Gly Gln
                 215                 220                 225

 Ser


<210> 2608
<211> 1667
<212> DNA
<213> Homo sapien

<400> 2608
 gaaaactggc catgactaca gccagaactg ttatgagatt aacatttcta 50

 ttgagaagct tttgagtaaa gtactgtatt tgttcatgaa gatgactgag 100

 atggtaacac ttcgtgtagc ttaaggaaat gggcagaatt tcgtaaatgc 150

 tgttgtgcag atgtgttttc cctgaatgct ttcgtattag tggcgaccag 200

 tttctcacag aattgtgaag cctgaaggcc aagaggaagt cactgttaaa 250

 ggactctgtg ccatcttaca accttggatg aattatcctg ccaacgtgaa 300

 aacctcatgt tcaaagaaca cttcccttta gccgatgtaa ctgctggttt 350

 tgtttttcat atgtgttttt cttacactca tttgaatgct ttcaagcatt 400

 tgtaaactta aaaaatgtat aaagggcaaa aagtctgaac ccttgttttc 450

 tgaaatctaa tcagttatgt atggtttctg aagggtaatt ttattttgga 500

 ataggtaaag gaaacctgtt ttgtttgttt ttcctgaggg ctagatgctt 550

 tttttttctc acactcttaa tgacttttaa catttatact gagcatccat 600

 agatatattc ctagaagtat gagaagaatt attcttattg accattaatg 650

 tcatgttcat tttaatgtaa tataattgag atgaaatgtt ctctggttgg 700

 aacagatact ctcttttttt ttcttgcaat ctttaagaat acatagatct 750

 aaaattcatt agcttgaccc ctcaaagtaa cttttaagta aagattaaag 800

 cttttcttct cagtgaatat atctgctaga aggaaatagc tgggaagaat 850

 ttaatgatca gggaaattca ttatttctat atgtggaaac tttttgcttc 900

 gaatattgta tctttttaaa tctaaatgtt catatttttc ctgaagaaac 950

 cactgtgtaa aaatcaaatt ttaattttga atggaataat ttcaaagaac 1000

 tatgaagatg atttgaagct ctaatttata tagtcaccta taaaatgttc 1050

 tttatatgtg ttcataagta aattttatat tgattaagtt aaacttttga 1100

 attgatttga ggagcagtaa aatgaaagct atatctattc taaaccttat 1150

 ttagacattg gtaccagtta cccaggtgaa aatatggagt aactttgttt 1200

 tgtatggtaa ggtttaggaa tggtggatga agggtatctc tatataaata 1250

 aagtgctcaa caatgtgcaa tgattgtaaa tttagtaaga tattacagcc 1300

 atttcatgaa tgctttacca ttcaacatag tatctattac aaaacacctt 1350

 tcttgtatcc atatacttca ggtgttgctg ttaacattta ctatgatatt 1400

 tattttaacc aaaatgttac tcacattaaa tgtttattct ttaaaatgaa 1450

 tgtattatgt ttttaaccca caaatgcata cttaccctgt gcctcatatt 1500

 tcaatagtac tgtaatatgg acatcttttg tgaaatactt ttattttgtt 1550

 atgctttaaa tatacataca aaaagatttc tgttattagc tttgaaaatt 1600

 gtataatatc ctaatataaa caaaaatata aaaataaaaa tgaatacagt 1650

 aaaaaaaaaa aaaaaaa 1667

<210> 2609
<211> 40
<212> PRT
<213> Homo sapien

<400> 2609
 Lys Thr Gly His Asp Tyr Ser Gln Asn Cys Tyr Glu Ile Asn Ile
   1               5                  10                  15

 Ser Ile Glu Lys Leu Leu Ser Lys Val Leu Tyr Leu Phe Met Lys
                  20                  25                  30

 Met Thr Glu Met Val Thr Leu Arg Val Ala
                  35                  40

<210> 2610
<211> 7522
<212> DNA
<213> Homo sapien

<400> 2610
 gcggccgggc cgggccgcgg gagcaggcgg aggcggaggc ggcgggggca 50

 ggaggatgtc gcagccgccg ctgctccccg cctcggcgga gactcggaag 100

 ttcacccggg cgctgagtaa gccgggcacg gcggccgagc tgcggcagag 150

 cgtgtctgag gtggtgcgcg gctccgtgct cctggcaaag ccaaagctaa 200

 ttgagccact cgactatgaa aatgtcatcg tccagaagaa gactcagatc 250

 ctgaacgact gtttacggga gatgctgctc ttcccttacg atgactttca 300

 gacggccatc ctgagacgac agggtcgata catatgctca acagtgcctg 350

 cgaaggcgga agaggaagca cagagcttgt ttgttacaga gtgcatcaaa 400

 acctataact ctgactggca tcttgtgaac tataaatatg aagattactc 450

 aggagagttt cgacagcttc cgaacaaagt ggtcaagttg gataaacttc 500

 cagttcatgt ctatgaagtt gacgaggagg tcgacaaaga tgaggatgct 550

 gcctcccttg gttcccagaa gggtgggatc accaagcatg gctggctgta 600

 caaaggcaac atgaacagtg ccatcagcgt gaccatgagg tcatttaaga 650

 gacgattttt ccacctgatt caacttggcg atggatccta taatttgaat 700

 ttttataaag atgaaaagat ctccaaagaa ccaaaaggat caatatttct 750

 ggattcctgt atgggtgtcg ttcagaacaa caaagtcagg cgttttgctt 800

 ttgagctcaa gatgcaggac aaaagtagtt atctcttggc agcagacagt 850

 gaagtggaaa tggaagaatg gatcacaatt ctaaataaga tcctccagct 900

 caactttgaa gctgcaatgc aagaaaagcg aaatggcgac tctcacgaag 950

 atgatgaaca aagcaaattg gaaggttctg gttccggttt agatagctac 1000

 ctgccggaac ttgccaagag tgcaagagaa gcagaaatca aactgaaaag 1050

 tgaaagcaga gtcaaacttt tttatttgga cccagatgcc cagaagcttg 1100

 acttctcatc agctgagcca gaagtgaagt catttgaaga gaagtttgga 1150

 aaaaggatcc ttgtcaagtg caatgattta tctttcaatt tgcaatgctg 1200

 tgttgccgaa aatgaagaag gacccactac aaatgttgaa cctttctttg 1250

 ttactctatc cctgtttgac ataaaataca accggaagat ttctgccgat 1300

 ttccacgtag acctgaacca tttctcagtg aggcaaatgc tcgccaccac 1350

 gtccccggcg ctgatgaatg gcagtgggca gagcccatct gtcctcaagg 1400

 gcatccttca tgaagccgcc atgcagtatc cgaagcaggg aatattttca 1450

 gtcacttgtc ctcatccaga tatatttctt gtggccagaa ttgaaaaagt 1500

 ccttcagggg agcatcacac attgcgctga gccatatatg aaaagttcag 1550

 actcttctaa ggtggcccag aaggtgctga agaatgccaa gcaggcatgc 1600

 caaagactag gacagtatag aatgccattt gcttgggcag caaggacatt 1650

 gtttaaggat gcatctggaa atcttgacaa aaatgccaga ttttctgcca 1700

 tctacaggca agacagcaat aagctatcca atgatgacat gctcaagtta 1750

 cttgcagact ttcggaaacc tgagaagatg gctaagctcc cagtgatttt 1800

 aggcaatcta gacattacaa ttgataatgt ttcctcagac ttccctaatt 1850

 atgttaattc atcatacatt cccacaaaac aatttgaaac ctgcagtaaa 1900

 actcccatca cgtttgaagt ggaggaattt gtgccctgca taccaaaaca 1950

 cactcagcct tacaccatct acaccaatca cctttacgtt tatcctaagt 2000

 acttgaaata cgacagtcag aagtcttttg ccaaggctag aaatattgcg 2050

 atttgcattg aattcaaaga ttcagatgag gaagactctc agccccttaa 2100

 gtgcatttat ggcagacctg gtgggccagt tttcacaaga agcgcctttg 2150

 ctgcagtttt acaccatcac caaaacccag aattttatga tgagattaaa 2200

 atagagttgc ccactcagct gcatgaaaag caccacctgt tgctcacatt 2250

 cttccatgtc agctgtgaca actcaagtaa aggaagcacg aagaagaggg 2300

 atgtcgttga aacccaagtt ggctactcct ggcttcccct cctgaaagac 2350

 ggaagggtgg tgacaagcga gcagcacatc ccggtctcgg cgaaccttcc 2400

 ttcgggctat cttggctacc aggagcttgg gatgggcagg cattatggtc 2450

 cggaaattaa atgggtagat ggaggcaagc cactgctgaa aatttccact 2500

 catctggttt ctacagtgta tactcaggat cagcatttac ataatttttt 2550

 ccagtactgt cagaaaaccg aatctggagc ccaagcctta ggaaacgaac 2600

 ttgtaaagta ccttaagagt ctgcatgcga tggaaggcca cgtgatgatc 2650

 gccttcttgc ccactatcct aaaccagctg ttccgagtcc tcaccagagc 2700

 cacacaggaa gaagtcgcgg ttaacgtgac tcgggtcatt attcatgtgg 2750

 ttgcccagtg ccatgaggaa ggattggaga gccacttgag gtcatatgtt 2800

 aagtacgcgt ataaggctga gccatatgtt gcctctgaat acaagacagt 2850

 gcatgaagaa ctgaccaaat ccatgaccac gattctcaag ccttctgccg 2900

 atttcctcac cagcaacaaa ctactgaagt actcatggtt tttctttgat 2950

 gtactgatca aatctatggc tcagcatttg atagagaact ccaaagttaa 3000

 gttgctgcga aaccagagat ttcctgcatc ctatcatcat gcagtggaaa 3050

 ccgttgtaaa tatgctgatg ccacacatca ctcagaagtt tcgagataat 3100

 ccagaggcat ctaagaacgc gaatcatagc cttgctgtct tcatcaagag 3150

 atgtttcacc ttcatggaca ggggctttgt cttcaagcag atcaacaact 3200

 acattagctg ttttgctcct ggagacccaa agaccctctt tgaatacaag 3250

 tttgaatttc tccgtgtagt gtgcaaccat gaacattata ttccgttgaa 3300

 cttaccaatg ccatttggaa aaggcaggat tcaaagatac caagacctcc 3350

 agcttgacta ctcattaaca gatgagttct gcagaaacca cttcttggtg 3400

 ggactgttac tgagggaggt ggggacagcc ctccaggagt tccgggaggt 3450

 ccgtctgatc gccatcagtg tgctcaagaa cctgctgata aagcattctt 3500

 ttgatgacag atatgcttca aggagccatc aggcaaggat agccaccctc 3550

 tacctgcctc tgtttggtct gctgattgaa aacgtccagc ggatcaatgt 3600

 gagggatgtg tcacccttcc ctgtgaacgc gggcatgact gtgaaggatg 3650

 aatccctggc tctaccagct gtgaatccgc tggtgacgcc gcagaaggga 3700

 agcaccctgg acaacagcct gcacaaggac ctgctgggcg ccatctccgg 3750

 cattgcttct ccatatacaa cctcaactcc aaacatcaac agtgtgagaa 3800

 atgctgattc gagaggatct ctcataagca cagattcggg taacagcctt 3850

 ccagaaagga atagtgagaa gagcaattcc ctggataagc accaacaaag 3900

 tagcacattg ggaaattccg tggttcgctg tgataaactt gaccagtctg 3950

 agattaagag cctactgatg tgtttcctct acatcttaaa gagcatgtct 4000

 gatgatgctt tgtttacata ttggaacaag gcttcaacat ctgaacttat 4050

 ggattttttt acaatatctg aagtctgcct gcaccagttc cagtacatgg 4100

 ggaagcgata catagccaga acaggaatga tgcatgccag attgcagcag 4150

 ctgggcagcc tggataactc tctcactttt aaccacagct atggccactc 4200

 ggacgcagat gttctgcacc agtcattact tgaagccaac attgctactg 4250

 aggtttgcct gacagctctg gacacgcttt ctctatttac attggcgttt 4300

 aagaaccagc tcctggccga ccatggacat aatcctctca tgaaaaaagt 4350

 ttttgatgtc tacctgtgtt ttcttcaaaa acatcagtct gaaacggctt 4400

 taaaaaatgt cttcactgcc ttaaggtcct taatttataa gtttccctca 4450

 acattctatg aagggagagc ggacatgtgt gcggctctgt gttacgagat 4500

 tctcaagtgc tgtaactcca agctgagctc catcaggacg gaggcctccc 4550

 agctgctcta cttcctgatg aggaacaact ttgattacac tggaaagaag 4600

 tcctttgtcc ggacacattt gcaagtcatc atatctgtca gccagctgat 4650

 agcagacgtt gttggcattg ggggaaccag attccagcag tccctgtcca 4700

 tcatcaacaa ctgtgccaac agtgaccggc ttattaagca caccagcttc 4750

 tcctctgatg tgaaggactt aaccaaaagg atacgcacgg tgctaatggc 4800

 caccgcccag atgaaggagc atgagaacga cccagagatg ctggtggacc 4850

 tccagtacag cctggccaaa tcctatgcca gcacgcccga gctcaggaag 4900

 acgtggctcg acagcatggc caggatccat gtcaaaaatg gcgatctctc 4950

 agaggcagca atgtgctatg tccacgtaac agccctagtg gcagaatatc 5000

 tcacacggaa agaagcagtc cagtgggagc cgccccttct cccccacagc 5050

 catagcgcct gcctgaggag gagccgggga ggcgtgttta gacaaggatg 5100

 caccgccttc agggtcatta ccccaaacat cgacgaggag gcctccatga 5150

 tggaagacgt ggggatgcag gatgtccatt tcaacgagga tgtgctgatg 5200

 gagctccttg agcagtgcgc agatggactc tggaaagccg agcgctacga 5250

 gctcattgcc gacatctaca aacttatcat ccccatttat gagaagcgga 5300

 gggattttga gaggctggcc catctgtatg acacgctgca ccgggcctac 5350

 agcaaagtga ccgaggtcat gcactcgggc cgcaggcttc tggggaccta 5400

 cttccgggta gccttcttcg ggcaggcagc gcaataccag tttacagaca 5450

 gtgaaacaga tgtggaggga ttctttgaag atgaagatgg aaaggagtat 5500

 atttacaagg aacccaaact cacaccgctg tcggaaattt ctcagagact 5550

 ccttaaactg tactcggata aatttggttc tgaaaatgtc aaaatgatac 5600

 aggattctgg caaggtcaac cctaaggatc tggattctaa gtatgcctac 5650

 atccaggtga ctcacgtcat ccccttcttt gacgaaaaag agttgcaaga 5700

 aaggaaaaca gagtttgaga gatcccacaa catccgccgc ttcatgtttg 5750

 agatgccatt tacgcagacc gggaagaggc agggcggggt ggaagagcag 5800

 tgcaaacggc gcaccatcct gacagccata cactgcttcc cttatgtgaa 5850

 gaagcgcatc cctgtcatgt accagcacca cactgacctg aaccccatcg 5900

 aggtggccat tgacgagatg agtaagaagg tggcggagct ccggcagctg 5950

 tgctcctcgg ccgaggtgga catgatcaaa ctgcagctca aactccaggg 6000

 cagcgtgagt gttcaggtca atgctggccc actagcatat gcgcgagctt 6050

 tcttagatga tacaaacaca aagcgatatc ctgacaataa agtgaagctg 6100

 cttaaggaag ttttcaggca atttgtggaa gcttgcggtc aagccttagc 6150

 ggtaaacgaa cgtctgatta aagaagacca gctcgagtat caggaagaaa 6200

 tgaaagccaa ctacagggaa atggcgaagg agctttctga aatcatgcat 6250

 gagcagctgg gatgatctgc cccctggagg agaagacgag cgtcttaccg 6300

 aattcccttc acatcttcaa cgccatcagt gggactccaa caagcacaat 6350

 ggttcacggg atgaccagct cgtcttcggt cgtgtgatta catctcatgg 6400

 cccgtgtgtg gggacttgct ttgtcatttg caaactcagg atgctttcca 6450

 aagccaatca ctggggagac cgagcacagg gaggaccagg ggaaggggag 6500

 agaaaggaaa taaagaacaa cgttatttct taacagactt tctataggag 6550

 ttgtaagaag gtgcacatat ttttttaaat ctcactggca atattcaaag 6600

 ttttcattgt gtcttaacaa aggtgtggta gacactcttg agctggactt 6650

 agattttatt cttccttgca gagtagtgtt agaatagatg gcctacagaa 6700

 aaaaaaggtt ctgggatcta catggcaggg agggctgcac tgacattgat 6750

 gcctggggga ccttttgcct cgaggctgag ctggaaaatc ttgaaaatat 6800

 tttttttttc ctgtggcaca ttcaggttga atacaagaac tatttttgtg 6850

 actagttttt gatgacctaa gggaactgac cattgtaatt tttgtaccag 6900

 tgaaccagga gatttagtgc ttttatattc atttccttgc atttaagaaa 6950

 atatgaaagc ttaaggaatt atgtgagctt aaaactagtc aagcagttta 7000

 gaaccaaagg cctatattaa taaccgcaac tatgctgaaa agtacaaagt 7050

 agtacagtat attgttatgt acatatcatt gttaatacag tcctggcatt 7100

 ctgtacatat atgtattaca tttctacatt tttaatactc acatgggctt 7150

 atgcattaag tttaattgtg ataaatttgt gctgttccag tatatgcaat 7200

 acactttaat gttttattct tgtacataaa aatgtgcaat atggagatgt 7250

 atacagtctt tactatatta ggtttataaa cagttttaag aatttcatcc 7300

 ttttgccaaa atggtggagt atgtaattgg taaatcataa atcctgtggt 7350

 gaatggtggt gtactttaaa gctgtcacca tgttatattt tcttttaaga 7400

 cattaattta gtaattttat atttgggaaa ataaaggttt ttaattttat 7450

 ttaactggaa tcactgccct gctgtaatta aacattctgt accacatctg 7500

 tattaaaaag acattgctga cc 7522

<210> 2611
<211> 2000
<212> PRT
<213> Homo sapien

<400> 2611
 Met Ser Gln Pro Pro Leu Leu Pro Ala Ser Ala Glu Thr Arg Lys
   1               5                  10                  15

 Phe Thr Arg Ala Leu Ser Lys Pro Gly Thr Ala Ala Glu Leu Arg
                  20                  25                  30

 Gln Ser Val Ser Glu Val Val Arg Gly Ser Val Leu Leu Ala Lys
                  35                  40                  45

 Pro Lys Leu Ile Glu Pro Leu Asp Tyr Glu Asn Val Ile Val Gln
                  50                  55                  60

 Lys Lys Thr Gln Ile Leu Asn Asp Cys Leu Arg Glu Met Leu Leu
                  65                  70                  75

 Phe Pro Tyr Asp Asp Phe Gln Thr Ala Ile Leu Arg Arg Gln Gly
                  80                  85                  90

 Arg Tyr Ile Cys Ser Thr Val Pro Ala Lys Ala Glu Glu Glu Ala
                  95                 100                 105

 Gln Ser Leu Phe Val Thr Glu Cys Ile Lys Thr Tyr Asn Ser Asp
                 110                 115                 120

 Trp His Leu Val Asn Tyr Lys Tyr Glu Asp Tyr Ser Gly Glu Phe
                 125                 130                 135

 Arg Gln Leu Pro Asn Lys Val Val Lys Leu Asp Lys Leu Pro Val
                 140                 145                 150

 His Val Tyr Glu Val Asp Glu Glu Val Asp Lys Asp Glu Asp Ala
                 155                 160                 165

 Ala Ser Leu Gly Ser Gln Lys Gly Gly Ile Thr Lys His Gly Trp
                 170                 175                 180

 Leu Tyr Lys Gly Asn Met Asn Ser Ala Ile Ser Val Thr Met Arg
                 185                 190                 195

 Ser Phe Lys Arg Arg Phe Phe His Leu Ile Gln Leu Gly Asp Gly
                 200                 205                 210

 Ser Tyr Asn Leu Asn Phe Tyr Lys Asp Glu Lys Ile Ser Lys Glu
                 215                 220                 225

 Pro Lys Gly Ser Ile Phe Leu Asp Ser Cys Met Gly Val Val Gln
                 230                 235                 240

 Asn Asn Lys Val Arg Arg Phe Ala Phe Glu Leu Lys Met Gln Asp
                 245                 250                 255

 Lys Ser Ser Tyr Leu Leu Ala Ala Asp Ser Glu Val Glu Met Glu
                 260                 265                 270

 Glu Trp Ile Thr Ile Leu Asn Lys Ile Leu Gln Leu Asn Phe Glu
                 275                 280                 285

 Ala Ala Met Gln Glu Lys Arg Asn Gly Asp Ser His Glu Asp Asp
                 290                 295                 300

 Glu Gln Ser Lys Leu Glu Gly Ser Gly Ser Gly Leu Asp Ser Tyr
                 305                 310                 315

 Leu Pro Glu Leu Ala Lys Ser Ala Arg Glu Ala Glu Ile Lys Leu
                 320                 325                 330

 Lys Ser Glu Ser Arg Val Lys Leu Phe Tyr Leu Asp Pro Asp Ala
                 335                 340                 345

 Gln Lys Leu Asp Phe Ser Ser Ala Glu Pro Glu Val Lys Ser Phe
                 350                 355                 360

 Glu Glu Lys Phe Gly Lys Arg Ile Leu Val Lys Cys Asn Asp Leu
                 365                 370                 375

 Ser Phe Asn Leu Gln Cys Cys Val Ala Glu Asn Glu Glu Gly Pro
                 380                 385                 390

 Thr Thr Asn Val Glu Pro Phe Phe Val Thr Leu Ser Leu Phe Asp
                 395                 400                 405

 Ile Lys Tyr Asn Arg Lys Ile Ser Ala Asp Phe His Val Asp Leu
                 410                 415                 420

 Asn His Phe Ser Val Arg Gln Met Leu Ala Thr Thr Ser Pro Ala
                 425                 430                 435

 Leu Met Asn Gly Ser Gly Gln Ser Pro Ser Val Leu Lys Gly Ile
                 440                 445                 450

 Leu His Glu Ala Ala Met Gln Tyr Pro Lys Gln Gly Ile Phe Ser
                 455                 460                 465

 Val Thr Cys Pro His Pro Asp Ile Phe Leu Val Ala Arg Ile Glu
                 470                 475                 480

 Lys Val Leu Gln Gly Ser Ile Thr His Cys Ala Glu Pro Tyr Met
                 485                 490                 495

 Lys Ser Ser Asp Ser Ser Lys Val Ala Gln Lys Val Leu Lys Asn
                 500                 505                 510

 Ala Lys Gln Ala Cys Gln Arg Leu Gly Gln Tyr Arg Met Pro Phe
                 515                 520                 525

 Ala Trp Ala Ala Arg Thr Leu Phe Lys Asp Ala Ser Gly Asn Leu
                 530                 535                 540

 Asp Lys Asn Ala Arg Phe Ser Ala Ile Tyr Arg Gln Asp Ser Asn
                 545                 550                 555

 Lys Leu Ser Asn Asp Asp Met Leu Lys Leu Leu Ala Asp Phe Arg
                 560                 565                 570

 Lys Pro Glu Lys Met Ala Lys Leu Pro Val Ile Leu Gly Asn Leu
                 575                 580                 585

 Asp Ile Thr Ile Asp Asn Val Ser Ser Asp Phe Pro Asn Tyr Val
                 590                 595                 600

 Asn Ser Ser Tyr Ile Pro Thr Lys Gln Phe Glu Thr Cys Ser Lys
                 605                 610                 615

 Thr Pro Ile Thr Phe Glu Val Glu Glu Phe Val Pro Cys Ile Pro
                 620                 625                 630

 Lys His Thr Gln Pro Tyr Thr Ile Tyr Thr Asn His Leu Tyr Val
                 635                 640                 645

 Tyr Pro Lys Tyr Leu Lys Tyr Asp Ser Gln Lys Ser Phe Ala Lys
                 650                 655                 660

 Ala Arg Asn Ile Ala Ile Cys Ile Glu Phe Lys Asp Ser Asp Glu
                 665                 670                 675

 Glu Asp Ser Gln Pro Leu Lys Cys Ile Tyr Gly Arg Pro Gly Gly
                 680                 685                 690

 Pro Val Phe Thr Arg Ser Ala Phe Ala Ala Val Leu His His His
                 695                 700                 705

 Gln Asn Pro Glu Phe Tyr Asp Glu Ile Lys Ile Glu Leu Pro Thr
                 710                 715                 720

 Gln Leu His Glu Lys His His Leu Leu Leu Thr Phe Phe His Val
                 725                 730                 735

 Ser Cys Asp Asn Ser Ser Lys Gly Ser Thr Lys Lys Arg Asp Val
                 740                 745                 750

 Val Glu Thr Gln Val Gly Tyr Ser Trp Leu Pro Leu Leu Lys Asp
                 755                 760                 765

 Gly Arg Val Val Thr Ser Glu Gln His Ile Pro Val Ser Ala Asn
                 770                 775                 780

 Leu Pro Ser Gly Tyr Leu Gly Tyr Gln Glu Leu Gly Met Gly Arg
                 785                 790                 795

 His Tyr Gly Pro Glu Ile Lys Trp Val Asp Gly Gly Lys Pro Leu
                 800                 805                 810

 Leu Lys Ile Ser Thr His Leu Val Ser Thr Val Tyr Thr Gln Asp
                 815                 820                 825

 Gln His Leu His Asn Phe Phe Gln Tyr Cys Gln Lys Thr Glu Ser
                 830                 835                 840

 Gly Ala Gln Ala Leu Gly Asn Glu Leu Val Lys Tyr Leu Lys Ser
                 845                 850                 855

 Leu His Ala Met Glu Gly His Val Met Ile Ala Phe Leu Pro Thr
                 860                 865                 870

 Ile Leu Asn Gln Leu Phe Arg Val Leu Thr Arg Ala Thr Gln Glu
                 875                 880                 885

 Glu Val Ala Val Asn Val Thr Arg Val Ile Ile His Val Val Ala
                 890                 895                 900

 Gln Cys His Glu Glu Gly Leu Glu Ser His Leu Arg Ser Tyr Val
                 905                 910                 915

 Lys Tyr Ala Tyr Lys Ala Glu Pro Tyr Val Ala Ser Glu Tyr Lys
                 920                 925                 930

 Thr Val His Glu Glu Leu Thr Lys Ser Met Thr Thr Ile Leu Lys
                 935                 940                 945

 Pro Ser Ala Asp Phe Leu Thr Ser Asn Lys Leu Leu Lys Tyr Ser
                 950                 955                 960

 Trp Phe Phe Phe Asp Val Leu Ile Lys Ser Met Ala Gln His Leu
                 965                 970                 975

 Ile Glu Asn Ser Lys Val Lys Leu Leu Arg Asn Gln Arg Phe Pro
                 980                 985                 990

 Ala Ser Tyr His His Ala Val Glu Thr Val Val Asn Met Leu Met
                 995                1000                1005

 Pro His Ile Thr Gln Lys Phe Arg Asp Asn Pro Glu Ala Ser Lys
                1010                1015                1020

 Asn Ala Asn His Ser Leu Ala Val Phe Ile Lys Arg Cys Phe Thr
                1025                1030                1035

 Phe Met Asp Arg Gly Phe Val Phe Lys Gln Ile Asn Asn Tyr Ile
                1040                1045                1050

 Ser Cys Phe Ala Pro Gly Asp Pro Lys Thr Leu Phe Glu Tyr Lys
                1055                1060                1065

 Phe Glu Phe Leu Arg Val Val Cys Asn His Glu His Tyr Ile Pro
                1070                1075                1080

 Leu Asn Leu Pro Met Pro Phe Gly Lys Gly Arg Ile Gln Arg Tyr
                1085                1090                1095

 Gln Asp Leu Gln Leu Asp Tyr Ser Leu Thr Asp Glu Phe Cys Arg
                1100                1105                1110

 Asn His Phe Leu Val Gly Leu Leu Leu Arg Glu Val Gly Thr Ala
                1115                1120                1125

 Leu Gln Glu Phe Arg Glu Val Arg Leu Ile Ala Ile Ser Val Leu
                1130                1135                1140

 Lys Asn Leu Leu Ile Lys His Ser Phe Asp Asp Arg Tyr Ala Ser
                1145                1150                1155

 Arg Ser His Gln Ala Arg Ile Ala Thr Leu Tyr Leu Pro Leu Phe
                1160                1165                1170

 Gly Leu Leu Ile Glu Asn Val Gln Arg Ile Asn Val Arg Asp Val
                1175                1180                1185

 Ser Pro Phe Pro Val Asn Ala Gly Met Thr Val Lys Asp Glu Ser
                1190                1195                1200

 Leu Ala Leu Pro Ala Val Asn Pro Leu Val Thr Pro Gln Lys Gly
                1205                1210                1215

 Ser Thr Leu Asp Asn Ser Leu His Lys Asp Leu Leu Gly Ala Ile
                1220                1225                1230

 Ser Gly Ile Ala Ser Pro Tyr Thr Thr Ser Thr Pro Asn Ile Asn
                1235                1240                1245

 Ser Val Arg Asn Ala Asp Ser Arg Gly Ser Leu Ile Ser Thr Asp
                1250                1255                1260

 Ser Gly Asn Ser Leu Pro Glu Arg Asn Ser Glu Lys Ser Asn Ser
                1265                1270                1275

 Leu Asp Lys His Gln Gln Ser Ser Thr Leu Gly Asn Ser Val Val
                1280                1285                1290

 Arg Cys Asp Lys Leu Asp Gln Ser Glu Ile Lys Ser Leu Leu Met
                1295                1300                1305

 Cys Phe Leu Tyr Ile Leu Lys Ser Met Ser Asp Asp Ala Leu Phe
                1310                1315                1320

 Thr Tyr Trp Asn Lys Ala Ser Thr Ser Glu Leu Met Asp Phe Phe
                1325                1330                1335

 Thr Ile Ser Glu Val Cys Leu His Gln Phe Gln Tyr Met Gly Lys
                1340                1345                1350

 Arg Tyr Ile Ala Arg Thr Gly Met Met His Ala Arg Leu Gln Gln
                1355                1360                1365

 Leu Gly Ser Leu Asp Asn Ser Leu Thr Phe Asn His Ser Tyr Gly
                1370                1375                1380

 His Ser Asp Ala Asp Val Leu His Gln Ser Leu Leu Glu Ala Asn
                1385                1390                1395

 Ile Ala Thr Glu Val Cys Leu Thr Ala Leu Asp Thr Leu Ser Leu
                1400                1405                1410

 Phe Thr Leu Ala Phe Lys Asn Gln Leu Leu Ala Asp His Gly His
                1415                1420                1425

 Asn Pro Leu Met Lys Lys Val Phe Asp Val Tyr Leu Cys Phe Leu
                1430                1435                1440

 Gln Lys His Gln Ser Glu Thr Ala Leu Lys Asn Val Phe Thr Ala
                1445                1450                1455

 Leu Arg Ser Leu Ile Tyr Lys Phe Pro Ser Thr Phe Tyr Glu Gly
                1460                1465                1470

 Arg Ala Asp Met Cys Ala Ala Leu Cys Tyr Glu Ile Leu Lys Cys
                1475                1480                1485

 Cys Asn Ser Lys Leu Ser Ser Ile Arg Thr Glu Ala Ser Gln Leu
                1490                1495                1500

 Leu Tyr Phe Leu Met Arg Asn Asn Phe Asp Tyr Thr Gly Lys Lys
                1505                1510                1515

 Ser Phe Val Arg Thr His Leu Gln Val Ile Ile Ser Val Ser Gln
                1520                1525                1530

 Leu Ile Ala Asp Val Val Gly Ile Gly Gly Thr Arg Phe Gln Gln
                1535                1540                1545

 Ser Leu Ser Ile Ile Asn Asn Cys Ala Asn Ser Asp Arg Leu Ile
                1550                1555                1560

 Lys His Thr Ser Phe Ser Ser Asp Val Lys Asp Leu Thr Lys Arg
                1565                1570                1575

 Ile Arg Thr Val Leu Met Ala Thr Ala Gln Met Lys Glu His Glu
                1580                1585                1590

 Asn Asp Pro Glu Met Leu Val Asp Leu Gln Tyr Ser Leu Ala Lys
                1595                1600                1605

 Ser Tyr Ala Ser Thr Pro Glu Leu Arg Lys Thr Trp Leu Asp Ser
                1610                1615                1620

 Met Ala Arg Ile His Val Lys Asn Gly Asp Leu Ser Glu Ala Ala
                1625                1630                1635

 Met Cys Tyr Val His Val Thr Ala Leu Val Ala Glu Tyr Leu Thr
                1640                1645                1650

 Arg Lys Glu Ala Val Gln Trp Glu Pro Pro Leu Leu Pro His Ser
                1655                1660                1665

 His Ser Ala Cys Leu Arg Arg Ser Arg Gly Gly Val Phe Arg Gln
                1670                1675                1680

 Gly Cys Thr Ala Phe Arg Val Ile Thr Pro Asn Ile Asp Glu Glu
                1685                1690                1695

 Ala Ser Met Met Glu Asp Val Gly Met Gln Asp Val His Phe Asn
                1700                1705                1710

 Glu Asp Val Leu Met Glu Leu Leu Glu Gln Cys Ala Asp Gly Leu
                1715                1720                1725

 Trp Lys Ala Glu Arg Tyr Glu Leu Ile Ala Asp Ile Tyr Lys Leu
                1730                1735                1740

 Ile Ile Pro Ile Tyr Glu Lys Arg Arg Asp Phe Glu Arg Leu Ala
                1745                1750                1755

 His Leu Tyr Asp Thr Leu His Arg Ala Tyr Ser Lys Val Thr Glu
                1760                1765                1770

 Val Met His Ser Gly Arg Arg Leu Leu Gly Thr Tyr Phe Arg Val
                1775                1780                1785

 Ala Phe Phe Gly Gln Ala Ala Gln Tyr Gln Phe Thr Asp Ser Glu
                1790                1795                1800

 Thr Asp Val Glu Gly Phe Phe Glu Asp Glu Asp Gly Lys Glu Tyr
                1805                1810                1815

 Ile Tyr Lys Glu Pro Lys Leu Thr Pro Leu Ser Glu Ile Ser Gln
                1820                1825                1830

 Arg Leu Leu Lys Leu Tyr Ser Asp Lys Phe Gly Ser Glu Asn Val
                1835                1840                1845

 Lys Met Ile Gln Asp Ser Gly Lys Val Asn Pro Lys Asp Leu Asp
                1850                1855                1860

 Ser Lys Tyr Ala Tyr Ile Gln Val Thr His Val Ile Pro Phe Phe
                1865                1870                1875

 Asp Glu Lys Glu Leu Gln Glu Arg Lys Thr Glu Phe Glu Arg Ser
                1880                1885                1890

 His Asn Ile Arg Arg Phe Met Phe Glu Met Pro Phe Thr Gln Thr
                1895                1900                1905

 Gly Lys Arg Gln Gly Gly Val Glu Glu Gln Cys Lys Arg Arg Thr
                1910                1915                1920

 Ile Leu Thr Ala Ile His Cys Phe Pro Tyr Val Lys Lys Arg Ile
                1925                1930                1935

 Pro Val Met Tyr Gln His His Thr Asp Leu Asn Pro Ile Glu Val
                1940                1945                1950

 Ala Ile Asp Glu Met Ser Lys Lys Val Ala Glu Leu Arg Gln Leu
                1955                1960                1965

 Cys Ser Ser Ala Glu Val Asp Met Ile Lys Leu Gln Leu Lys Leu
                1970                1975                1980

 Gln Gly Ser Val Ser Val Gln Val Asn Ala Gly Pro Leu Ala Tyr
                1985                1990                1995

 Ala Arg Ala Phe Leu
                2000

<210> 2612
<211> 2335
<212> DNA
<213> Homo sapien

<400> 2612
 gctttgcaga gtgattatca gcacagttcc ctgccctgga taaggaacag 50

 ctacagtcgc tgttaaatgt gcctgaaaag caatttgcaa tctttgcatt 100

 aggatttcag atgcatgcca ggtttccact gattgccaga actcgagatc 150

 actacacatg gatccccaaa atcaacatgg cagtggcagt tcgttagttg 200

 tgatccagca gccttctttg gatagccgtc agagattaga ctatgagaga 250

 gagattcagc ctactgctat tttgtcctta gaccagatca aggccataag 300

 aggcagcaat gaatacacag aagggccttc ggtggtgaaa agacctgctc 350

 ctcggacagc accaagacaa gaaaagcatg aaaggactca tgaaatcata 400

 ccaattaatg tgaataataa ctacgagcac agacacacaa gccacctggg 450

 acatgcagta ctcccaagta atgccagggg ccccattttg agcagatcaa 500

 ccagcactgg aagtgcagcc agctctggga gcaacagcag tgcctcttct 550

 gaacagggac tgttaggaag gtcaccacca accagaccag tccctggtca 600

 taggtctgaa agggcaatcc ggacccagcc caagcaactg attgtggatg 650

 acttgaaggg ttccttgaaa gaggacctga cacagcacaa gttcatttgt 700

 gaacagtgtg ggaagtgcaa gtgtggagaa tgcactgctc ccaggaccct 750

 accatcctgt ttggcctgta accggcagtg cctttgctct gctgagagca 800

 tggtggaata tggaacctgc atgtgcttag tcaagggcat cttctaccac 850

 tgctccaatg acgacgaagg ggattcctat tcagataatc cttgctcctg 900

 ttcacaatca cactgctgct ctagatacct gtgtatggga gccatgtctt 950

 tatttttacc ttgcttactc tgttatcctc ctgctaaagg atgcctgaag 1000

 ctgtgcagga ggtgttatga ctggatccat cgcccagggt gcagatgtaa 1050

 gaactccaac actgtctatt gtaagctgga gagctgcccc tcccggggtc 1100

 agggtaaacc atcatgattt ttggaggtgg gttgtacctc ctgaactttt 1150

 agctttcaag ttgtggctgt tttttgtttt tgtttttgtt tttgttttct 1200

 ttagaatttt tccctgtttc ccaccttctc ttcccctgtt gccaaggtct 1250

 aactcatgga tttttctctt tcctcatgga tgatcttcag caagagtgga 1300

 ctgggaagct gcacctggct cccactttca acaagagcct ctgccatcca 1350

 cttgagggta ttgagagcca gtgggctttt gtgtagcctt tttgttctgc 1400

 aagcaacttt ctaaagttgt gtacatgaac atacacccac atccagacta 1450

 cagtgattta gagttgtttt gattgggtac cgtgggagca gggaaattgg 1500

 ttttttaaaa agcaactgtt taattgctta aataagctat gtattaaatc 1550

 tgtctccagt tagggctatc ttcctagcat aggcccctta agtagcatgg 1600

 gggatatatt ttttgctata acgtaaaaat tttcctttaa ccactgccct 1650

 ctccttcttt ctccttcaag gttctttccc cctcagtttt gttgttgtct 1700

 tactctggag atgccaagtg tattttttct ttctatgtaa ttttagattc 1750

 gccttacaat gtaaatcttc acattggaga taatattggt tggaccttgc 1800

 ccatcttcac tctagccttc gtatttgtga aggactcagc caccttcctt 1850

 cttcacccca tgcttctcac caaatttttg ttgtcattga gggcacttgg 1900

 ataactcaag ttgatattta tagctgatca atctatatgt gtcacagaac 1950

 tatgctgcct aaagtgatct tggctcctta atggtccttt tggccccttg 2000

 gatagttaac agctgagtaa ttctaatctc ttctgtgttt tccttgcctt 2050

 aaccacaaat tgtggtgctt tttgtatatt ttatgtataa atcacaaagt 2100

 tgaattctga ctatttttaa gacaaaagtc tgttaaactt ttttattgta 2150

 aagaatattt attatgcgaa tctctattat tttatggtat ttattgcaaa 2200

 agactgttga aatgtactca tgtttgaata taacaaaata tcaatactta 2250

 acggaaaata aggtgacacg aagaaagtac atatgttaac tataatgcag 2300

 aaaatatatt aattaatgaa aaaaaaaaaa aaaaa 2335

<210> 2613
<211> 319
<212> PRT
<213> Homo sapien

<400> 2613
 Met Asp Pro Gln Asn Gln His Gly Ser Gly Ser Ser Leu Val Val
   1               5                  10                  15

 Ile Gln Gln Pro Ser Leu Asp Ser Arg Gln Arg Leu Asp Tyr Glu
                  20                  25                  30

 Arg Glu Ile Gln Pro Thr Ala Ile Leu Ser Leu Asp Gln Ile Lys
                  35                  40                  45

 Ala Ile Arg Gly Ser Asn Glu Tyr Thr Glu Gly Pro Ser Val Val
                  50                  55                  60

 Lys Arg Pro Ala Pro Arg Thr Ala Pro Arg Gln Glu Lys His Glu
                  65                  70                  75

 Arg Thr His Glu Ile Ile Pro Ile Asn Val Asn Asn Asn Tyr Glu
                  80                  85                  90

 His Arg His Thr Ser His Leu Gly His Ala Val Leu Pro Ser Asn
                  95                 100                 105

 Ala Arg Gly Pro Ile Leu Ser Arg Ser Thr Ser Thr Gly Ser Ala
                 110                 115                 120

 Ala Ser Ser Gly Ser Asn Ser Ser Ala Ser Ser Glu Gln Gly Leu
                 125                 130                 135

 Leu Gly Arg Ser Pro Pro Thr Arg Pro Val Pro Gly His Arg Ser
                 140                 145                 150

 Glu Arg Ala Ile Arg Thr Gln Pro Lys Gln Leu Ile Val Asp Asp
                 155                 160                 165

 Leu Lys Gly Ser Leu Lys Glu Asp Leu Thr Gln His Lys Phe Ile
                 170                 175                 180

 Cys Glu Gln Cys Gly Lys Cys Lys Cys Gly Glu Cys Thr Ala Pro
                 185                 190                 195

 Arg Thr Leu Pro Ser Cys Leu Ala Cys Asn Arg Gln Cys Leu Cys
                 200                 205                 210

 Ser Ala Glu Ser Met Val Glu Tyr Gly Thr Cys Met Cys Leu Val
                 215                 220                 225

 Lys Gly Ile Phe Tyr His Cys Ser Asn Asp Asp Glu Gly Asp Ser
                 230                 235                 240

 Tyr Ser Asp Asn Pro Cys Ser Cys Ser Gln Ser His Cys Cys Ser
                 245                 250                 255

 Arg Tyr Leu Cys Met Gly Ala Met Ser Leu Phe Leu Pro Cys Leu
                 260                 265                 270

 Leu Cys Tyr Pro Pro Ala Lys Gly Cys Leu Lys Leu Cys Arg Arg
                 275                 280                 285

 Cys Tyr Asp Trp Ile His Arg Pro Gly Cys Arg Cys Lys Asn Ser
                 290                 295                 300

 Asn Thr Val Tyr Cys Lys Leu Glu Ser Cys Pro Ser Arg Gly Gln
                 305                 310                 315

 Gly Lys Pro Ser


<210> 2614
<211> 11043
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 6964-6995
<223> Unknown base

<400> 2614
 ttgctgcgtc aactgtgttc cctttggcct ggctgagttt gatactgtgg 50

 ggattcagtt taggcgctgg cccgaggata tcccagcggt ggtacttcgg 100

 agacacctgt ctgcatctga ctgagccggc tctcctggcc tcgcgctgca 150

 cattctctcc tggcggcggc gccacctgca gtagcgttcg cccgaacatg 200

 gcgacacgga gcagcaggag ggagtcgcga ctcccgttcc tattcaccct 250

 ggtcgcactg ctgccgcccg gagctctctg cgaagtctgg acgcagaggc 300

 tgcacggcgg cagcgcgccc ttgccccagg accggggctt cctcgtggtg 350

 cagggcgacc cgcgcgagct gcggctgtgg gcgcgcgggg atgccagggg 400

 ggcgagccgc gcggacgaga agccgctccg gaggaaacgg agcgctgccc 450

 tgcagcccga gcccatcaag gtgtacggac aggttagtct gaatgattcc 500

 cacaatcaga tggtggtgca ctgggctgga gagaaaagca acgtgatcgt 550

 ggccttggcc cgagatagcc tggcattggc gaggcccaag agcagtgatg 600

 tgtacgtgtc ttacgactat ggaaaatcat tcaagaaaat ttcagacaag 650

 ttaaactttg gcttgggaaa taggagtgaa gctgttatcg cccagttcta 700

 ccacagccct gcggacaaca agcggtacat ctttgcagac gcttatgccc 750

 agtacctctg gatcacgttt gacttctgca acactcttca aggcttttcc 800

 atcccatttc gggcagctga tctcctccta cacagtaagg cctccaacct 850

 tctcttgggc tttgacaggt cccaccccaa caagcagctg tggaagtcag 900

 atgactttgg ccagacctgg atcatgattc aggaacatgt caagtccttt 950

 tcttggggaa ttgatcccta tgacaaacca aataccatct acattgaacg 1000

 acacgaaccc tctggctact ccactgtctt ccgaagtaca gatttcttcc 1050

 agtcccggga aaaccaggaa gtgatccttg aggaagtgag agattttcag 1100

 cttcgggaca agtacatgtt tgctacaaag gtggtgcatc tcttgggcag 1150

 tgaacagcag tcttctgtcc agctctgggt ctcctttggc cggaagccca 1200

 tgagagcagc ccagtttgtc acaagacatc ctattaatga atattacatc 1250

 gcagatgcct ccgaggacca ggtgtttgtg tgtgtcagcc acagtaacaa 1300

 ccgcaccaat ttatacatct cagaggcaga ggggctgaag ttctccctgt 1350

 ccttggagaa cgtgctctat tacagcccag gaggggccgg cagtgacacc 1400

 ttggtgaggt attttgcaaa tgaaccattt gctgacttcc accgagtgga 1450

 aggattgcaa ggagtctaca ttgctactct gattaatggt tctatgaatg 1500

 aggagaacat gagatcggtc atcacctttg acaaaggggg aacctgggag 1550

 tttcttcagg ctccagcctt cacgggatat ggagagaaaa tcaattgtga 1600

 gctttcccag ggctgttccc ttcatctggc tcagcgcctc agtcagctcc 1650

 tcaacctcca gctccggaga atgcccatcc tgtccaagga gtcggctcca 1700

 ggcctcatca tcgccactgg ctcagtggga aagaacttgg ctagcaagac 1750

 aaacgtgtac atctctagca gtgctggagc caggtggcga gaggcacttc 1800

 ctggacctca ctactacaca tggggagacc acggcggaat catcacggcc 1850

 attgcccagg gcatggaaac caacgagcta aaatacagta ccaatgaagg 1900

 ggagacctgg aaaacattca tcttctctga gaagccagtg tttgtgtatg 1950

 gcctcctcac agaacctggg gagaagagca ctgtcttcac catctttggc 2000

 tcgaacaaag agaatgtcca cagctggctg atcctccagg tcaatgccac 2050

 ggatgccttg ggagttccct gcacagagaa tgactacaag ctgtggtcac 2100

 catctgatga gcgggggaat gagtgtttgc tgggacacaa gactgttttc 2150

 aaacggcgga ccccccatgc cacatgcttc aatggagagg actttgacag 2200

 gccggtggtc gtgtccaact gctcctgcac ccgggaggac tatgagtgtg 2250

 acttcggttt caagatgagt gaagatttgt cattagaggt ttgtgttcca 2300

 gatccggaat tttctggaaa gtcatactcc cctcctgtgc cttgccctgt 2350

 gggttctact tacaggagaa cgagaggcta ccggaagatt tctggggaca 2400

 cttgtagcgg aggagatgtt gaagcgcgac tggaaggaga gctggtcccc 2450

 tgtcccctgg cagaagagaa cgagttcatt ctgtatgctg tgaggaaatc 2500

 catctaccgc tatgacctgg cctcgggagc caccgagcag ttgcctctca 2550

 ccgggctacg ggcagcagtg gccctggact ttgactatga gcacaactgt 2600

 ttgtattggt ccgacctggc cttggacgtc atccagcgcc tctgtttgaa 2650

 tggaagcaca gggcaagagg tgatcatcaa ttctggcctg gagacagtag 2700

 aagctttggc ttttgaaccc ctcagccagc tgctttactg ggtagatgca 2750

 ggcttcaaaa agattgaggt agctaatcca gatggcgact tccgactcac 2800

 aatcgtcaat tcctctgtgc ttgatcgtcc cagggctctg gtcctcgtgc 2850

 cccaagaggg ggtgatgttc tggacagact ggggagacct gaagcctggg 2900

 atttatcgga gcaatatgga tggttctgct gcctatcacc tggtgtctga 2950

 ggatgtgaag tggcccaatg gcatctctgt ggacgaccag tggatttact 3000

 ggacggatgc ctacctggag tgcatagagc ggatcacgtt cagtggccag 3050

 cagcgctctg tcattctgga caacctcccg cacccctatg ccattgctgt 3100

 ctttaagaat gaaatctact gggatgactg gtcacagctc agcatattcc 3150

 gagcttccaa atacagtggg tcccagatgg agattctggc aaaccagctc 3200

 acggggctca tggacatgaa gattttctac aaggggaaga acactggaag 3250

 caatgcctgt gtgcccaggc catgcagcct gctgtgcctg cccaaggcca 3300

 acaacagtag aagctgcagg tgtccagagg atgtgtccag cagtgtgctt 3350

 ccatcagggg acctgatgtg tgactgccct cagggctatc agctcaagaa 3400

 caatacctgt gtcaaagaag agaacacctg tcttcgcaac cagtatcgct 3450

 gcagcaacgg gaactgtatc aacagcattt ggtggtgtga ctttgacaac 3500

 gactgtggag acatgagcga tgagagaaac tgccctacca ccatctgtga 3550

 cctggacacc cagtttcgtt gccaggagtc tgggacttgt atcccactgt 3600

 cctataaatg tgaccttgag gatgactgtg gagacaacag tgatgaaagt 3650

 cattgtgaaa tgcaccagtg ccggagtgac gagtacaact gcagttccgg 3700

 catgtgcatc cgctcctcct gggtatgtga cggggacaac gactgcaggg 3750

 actggtctga tgaagccaac tgtaccgcca tctatcacac ctgtgaggcc 3800

 tccaacttcc agtgccgaaa cgggcactgc atcccccagc ggtgggcgtg 3850

 tgacggggat acggactgcc aggatggttc cgatgaggat ccagtcaact 3900

 gtgagaagaa gtgcaatgga ttccgctgcc caaacggcac ttgcatccca 3950

 tccagcaaac attgtgatgg tctgcgtgat tgctctgatg gctccgatga 4000

 acagcactgc gagcccctct gtacgcactt catggacttt gtgtgtaaga 4050

 accgccagca gtgcctgttc cactccatgg tctgtgacgg aatcatccag 4100

 tgccgcgacg ggtccgatga ggatgcggcg tttgcaggat gctcccaaga 4150

 tcctgagttc cacaaggtat gtgatgagtt cggtttccag tgtcagaatg 4200

 gagtgtgcat cagtttgatt tggaagtgcg acgggatgga tgattgcggc 4250

 gattattctg atgaagccaa ctgcgaaaac cccacagaag ccccaaactg 4300

 ctcccgctac ttccagtttc ggtgtgagaa tggccactgc atccccaaca 4350

 gatggaaatg tgacagggag aacgactgtg gggactggtc tgatgagaag 4400

 gattgtggag attcacatat tcttcccttc tcgactcctg ggccctccac 4450

 gtgtctgccc aattactacc gctgcagcag tgggacctgc gtgatggaca 4500

 cctgggtgtg cgacgggtac cgagattgtg cagatggctc tgacgaggaa 4550

 gcctgcccct tgcttgcaaa cgtcactgct gcctccactc ccacccaact 4600

 tgggcgatgt gaccgatttg agttcgaatg ccaccaaccg aagacgtgta 4650

 ttcccaactg gaagcgctgt gacggccacc aagattgcca ggatggccgg 4700

 gacgaggcca attgccccac acacagcacc ttgacttgca tgagcaggga 4750

 gttccagtgc gaggacgggg aggcctgcat tgtgctctcg gagcgctgcg 4800

 acggcttcct ggactgctcg gacgagagcg atgaaaaggc ctgcagtgat 4850

 gagttgactg tgtacaaagt acagaatctt cagtggacag ctgacttctc 4900

 tggggatgtg actttgacct ggatgaggcc caaaaaaatg ccctctgcat 4950

 cttgtgtata taatgtctac tacagggtgg ttggagagag catatggaag 5000

 actctggaga cccacagcaa taagacaaac actgtattaa aagtcttgaa 5050

 accagatacc acgtatcagg ttaaagtaca ggttcagtgt ctcagcaagg 5100

 cacacaacac caatgacttt gtgaccctga ggaccccaga gggattgcca 5150

 gatgcccctc gaaatctcca gctgtcactc cccagggaag cagaaggtgt 5200

 gattgtaggc cactgggctc ctcccatcca cacccatggc ctcatccgtg 5250

 agtacattgt agaatacagc aggagtggtt ccaagatgtg ggcctcccag 5300

 agggctgcta gtaactttac agaaatcaag aacttattgg tcaacactct 5350

 atacaccgtc agagtggctg cggtgactag tcgtggaata ggaaactgga 5400

 gcgattctaa atccattacc accataaaag gaaaagtgat cccaccacca 5450

 gatatccaca ttgacagcta tggtgaaaat tatctaagct tcaccctgac 5500

 catggagagt gatatcaagg tgaatggcta tgtggtgaac cttttctggg 5550

 catttgacac ccacaagcaa gagaggagaa ctttgaactt ccgaggaagc 5600

 atattgtcac acaaagttgg caatctgaca gctcatacat cctatgagat 5650

 ttctgcctgg gccaagactg acttggggga tagccctctg gcatttgagc 5700

 atgttatgac cagaggggtt cgcccacctg cacctagcct caaggccaaa 5750

 gccatcaacc agactgcagt ggaatgtacc tggaccggcc cccggaatgt 5800

 ggtttatggt attttctatg ccacgtcctt tcttgacctc tatcgcaacc 5850

 cgaagagctt gactacttca ctccacaaca agacggtcat tgtcagtaag 5900

 gatgagcagt atttgtttct ggtccgtgta gtggtaccct accaggggcc 5950

 atcctctgac tacgttgtag tgaagatgat cccggacagc aggcttccac 6000

 cccgtcacct gcatgtggtt catacgggca aaacctccgt ggtcatcaag 6050

 tgggaatcac cgtatgactc tcctgaccag gacttgttgt atgcaattgc 6100

 agtcaaagat ctcataagaa agactgacag gagctacaaa gtaaaatccc 6150

 gtaacagcac tgtggaatac acccttaaca agttggagcc tggcgggaaa 6200

 taccacatca ttgtccaact ggggaacatg agcaaagatt ccagcataaa 6250

 aattaccaca gtttcattat cagcacctga tgccttaaaa atcataacag 6300

 aaaatgatca tgttcttctg ttttggaaaa gcctggcttt aaaggaaaag 6350

 cattttaatg aaagcagggg ctatgagata cacatgtttg atagtgccat 6400

 gaatatcaca gcttaccttg ggaatactac tgacaatttc tttaaaattt 6450

 ccaacctgaa gatgggtcat aattacacgt tcaccgtcca agcaagatgc 6500

 ctttttggca accagatctg tggggagcct gccatcctgc tgtacgatga 6550

 gctggggtct ggtgcagatg catctgcaac gcaggctgcc agatctacgg 6600

 atgttgctgc tgtggtggtg cccatcttat tcctgatact gctgagcctg 6650

 ggggtggggt ttgccatcct gtacacgaag caccggaggc tgcagagcag 6700

 cttcaccgcc ttcgccaaca gccactacag ctccaggctg gggtccgcaa 6750

 tcttctcctc tggggatgac ctgggggaag atgatgaaga tgcccctatg 6800

 ataactggat tttcagatga cgtccccatg gtgatagcct gaaagagctt 6850

 tcctcactag aaaccaaatg gtgtaaatat tttatttgat aaagatagtt 6900

 gatggtttat tttaaaagat gcactttgag ttgcaatatg ttatttttat 6950

 atgggccaaa aacnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnggaat 7000

 gaataaactt tgtagtaatc aactgtgaac ttcaaaccag gttgatttta 7050

 gtaacccaat tgctttgatt tgacattaat gtagtcttac agggctgtgc 7100

 ttgctgggca tgcttttacg tctgtgagat aatttcggtt cagtaaattg 7150

 gccaatcttt ttatttttct aagacacaga aatgtattta ataaaaacct 7200

 cgagagagtg atgggtggaa ccccttctcc ttgaaagtgt gtacagatat 7250

 tccattttgt ttggatatag tttataggaa agtgtgtgga tgtattatgg 7300

 cggaaggttt ctttatgtta ttttgttaat ttattgggac tctgtgtaag 7350

 gccaggcttt agtggtcatt agacaccaca tgtgttatga gccccttacc 7400

 catagggttg ggggtgggaa gagaagcata tttttttgcc attccggaag 7450

 caatccattt ttattcactt gtgtgtcatg taatggtctt tggcaggaga 7500

 gagcactgag tcattgctgg agttcagttc aacagagctg cagcttggga 7550

 agccctgtaa gcccacagct tcctctctta tattaattga tggaatttta 7600

 ctgtatgtgc ctctgtacaa gatgtagctt tgagagctac aaaatgataa 7650

 cactgcttta ttacacactg gtttcattgt cattgcaaaa acttaccctg 7700

 gttgtggggg agagttctag atctgtgcca tgatccatac actggctaat 7750

 agagtacata atttttccat tttccatttt ttgtttttac ttactactga 7800

 aggatctcag atgtaaaatt atgtatttgg tttgagatgg ccacttattg 7850

 tccttaaaaa tccatactga tatatgcagt cattttgaat tggacagtgc 7900

 cttctctttt tttttctcct cttcttccat ctccctcacc catgccccca 7950

 cccaatctaa agagacagtg ctgtacattc tcatagagat agagaagatc 8000

 taaaaagttg agactactca atccagttaa caacagcagg agcactagag 8050

 tttgttcatt tattctctct gtaaaacaag ctgtgctttt tttcttctgc 8100

 ctttaaaatg ccacccgtgt attcaaacca tggccacttg atacttatgt 8150

 agaatccatc gtgggctgat gcaagccctt tatttaggct tagtgttgtg 8200

 ggcaccaatg tcgagcatcg ttgtgacttg tgctgtatga ttctcactga 8250

 agaatttcct ttcagccaag aagcagtgag gtctgggaat attccaaagt 8300

 catgtctctg aatatgtgtc cttgacgtgc aagctttgta aaaccccatc 8350

 cccgcttagg tgcgaggcat caccttctca caagtgttta gtttctttta 8400

 accacaagta tcattcttgg gtgataatat agtttcattc tacttaggga 8450

 ttgtttagaa aacaaagaaa gagccaatta aattttttag tttttgaaat 8500

 ttttatttat atgtatactt agatgagtat tttaagctgt cgacctttag 8550

 tttgccatac gggtaggact gtatttcatg ttaacaactg gtggtaatga 8600

 taagccttct tctagcgtat tttctcttct ttcctgtcac tttcctaagt 8650

 tttttttttt aaagactgga attttttttg gctttatctt gtcttaccgt 8700

 agagatttgt tcaaaactct aagccctacc acctcccctt taataagctc 8750

 tttaaatagt tgaatcatta acaacctggt gggaggcaag tcatttaatt 8800

 gaaccactag gaagtgtatt ttcttttctt tttctgccaa ctttttggtg 8850

 gcatttgtaa aagctgatat aaaaggctct gagatgttat tttcagttat 8900

 tccataggca agccttttta cagagcatat gtctccagtt ggcagcttga 8950

 gatatttccg agcatccggt tctagctacc agtgcctccc aatgcttagt 9000

 gcacagtact gtagactggc catcacccct ctccttggaa aatgccactg 9050

 tgctgtttga aaaaaagcag ccttttaggg ctagagtatt ttatataaac 9100

 agaagagcta agttcctgaa gactaagcta gatagctgca gctatatgta 9150

 aattgtatat ttttatgaac ttttgaagca cacactcctg tttccctctg 9200

 tgtagctttg tggggatttc atgtatatat gctgtctgaa agaatccaga 9250

 ggttggagtg ccaatagaaa atgaaaacaa atgccttgta ctacaggcag 9300

 cctctgaagg tgaccacata actgtcttca ctgtgaccaa tcggagtccc 9350

 tgcttgcttg tgaagaaggg gcttttgtac cttgttggag atgccacctc 9400

 agaagttcac actgtgcagg aaaaaggttt tattctctcc tggcatacat 9450

 tagaatgtca gatgcctgca tccatgtgga ccacgatggg cctctaaaaa 9500

 ttggtgggca gggggtttgc ttatgagttt tctctggaaa ccgattttac 9550

 tcctggatgt attgaatgcc ccttgagctt tatgagatac gagtccacat 9600

 ggataaaatg ttagagagtg gagttctaca gaggattcca ggaagaggcc 9650

 atgtctgtgc agtcctagtt ccagacaggt gagaagctcc aggaactact 9700

 ggctaccttg acaagctggg taaatagtta tcattctggg taactggttg 9750

 aaactctgac ttttggacaa gtaattcctg gggttctgtc tttggtagca 9800

 tcaccaggga tatttgggtg ggacagacag aagacacaca gctgcctgtt 9850

 ctctcctgcc catcatgttt ggcccactag atgaagctgt actcagcaat 9900

 ttagggaatg taacccttct cagaactggc cattttcagg ggaagcttgg 9950

 gagagcaata gtatggtgag ccccttagag atgagcgcct actccttctt 10000

 ggcgaatgct gccttcagat gcttaccaag tggtcactgc atctagtaag 10050

 attatatttc cagtacactt ccttagggca gaaacaccat cctatcaggt 10100

 ttggtcagtc ccttcttcat gaagggagtc atggggaatt cctgaaaatt 10150

 ttcttccttc tgcagacagt tggatgagtc ccttagagaa ggcatccaga 10200

 gacataacta aactgaatat catcccatat tgattttagg aattgactct 10250

 aaaactctgt gcagaatctt gtgttgggat tgtatcttga cattcctgtt 10300

 gtgttatttt tcttaactgg agtgtgtgct gcctttcagg tacaattttt 10350

 gtgtaataaa agccagtgca ttaagtttat atagactact ttctatgcaa 10400

 gactgagata tggaatagat aggaagagat atgtactgct gggtacatgg 10450

 acagtaagtg tgttttcaga tggagtacca gcaccgaaaa tgggttgagg 10500

 gaggatgggt tgtatgtatg tttctgccca ctaattttga gcagccatat 10550

 tatgaattaa atcgtcacag ccaagtaata acccaagaat ggtatgagtt 10600

 tcatgtgtaa tagctcaaat ggaataagca tgaatgctgg agtggaccat 10650

 tatcctcaaa tattctatgt cacttctcat ttaaagactc ttgttatgaa 10700

 ctattagaaa ctttaggcaa aatcaaaagt atttgcggca aaataaaggc 10750

 ctattctact cttatttaaa gtgaaacact gtatacttgt ttctctccaa 10800

 agcgaaatta agtatttata atttcaattg cctcgataag tttccaagtc 10850

 actgaaatct gctgaaggtt ttactgtatt gttgcacaac tttaagataa 10900

 tttttgtctc aatgtcaact tttttcactg aataaaaatt taactgggtc 10950

 aagaaaacac ctctttgaaa atccactgtc tctgtgtgtc tcgagctgtt 11000

 ctttagagcg caataaagat ggctgacgca gtctccaaac ccc 11043

<210> 2615
<211> 2279
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 6964-6995
<223> Unknown amino acid

<400> 2615
 Ala Ala Ser Thr Val Phe Pro Leu Ala Trp Leu Ser Leu Ile Leu
   1               5                  10                  15

 Trp Gly Phe Ser Leu Gly Ala Gly Pro Arg Ile Ser Gln Arg Trp
                  20                  25                  30

 Tyr Phe Gly Asp Thr Cys Leu His Leu Thr Glu Pro Ala Leu Leu
                  35                  40                  45

 Ala Ser Arg Cys Thr Phe Ser Pro Gly Gly Gly Ala Thr Cys Ser
                  50                  55                  60

 Ser Val Arg Pro Asn Met Ala Thr Arg Ser Ser Arg Arg Glu Ser
                  65                  70                  75

 Arg Leu Pro Phe Leu Phe Thr Leu Val Ala Leu Leu Pro Pro Gly
                  80                  85                  90

 Ala Leu Cys Glu Val Trp Thr Gln Arg Leu His Gly Gly Ser Ala
                  95                 100                 105

 Pro Leu Pro Gln Asp Arg Gly Phe Leu Val Val Gln Gly Asp Pro
                 110                 115                 120

 Arg Glu Leu Arg Leu Trp Ala Arg Gly Asp Ala Arg Gly Ala Ser
                 125                 130                 135

 Arg Ala Asp Glu Lys Pro Leu Arg Arg Lys Arg Ser Ala Ala Leu
                 140                 145                 150

 Gln Pro Glu Pro Ile Lys Val Tyr Gly Gln Val Ser Leu Asn Asp
                 155                 160                 165

 Ser His Asn Gln Met Val Val His Trp Ala Gly Glu Lys Ser Asn
                 170                 175                 180

 Val Ile Val Ala Leu Ala Arg Asp Ser Leu Ala Leu Ala Arg Pro
                 185                 190                 195

 Lys Ser Ser Asp Val Tyr Val Ser Tyr Asp Tyr Gly Lys Ser Phe
                 200                 205                 210

 Lys Lys Ile Ser Asp Lys Leu Asn Phe Gly Leu Gly Asn Arg Ser
                 215                 220                 225

 Glu Ala Val Ile Ala Gln Phe Tyr His Ser Pro Ala Asp Asn Lys
                 230                 235                 240

 Arg Tyr Ile Phe Ala Asp Ala Tyr Ala Gln Tyr Leu Trp Ile Thr
                 245                 250                 255

 Phe Asp Phe Cys Asn Thr Leu Gln Gly Phe Ser Ile Pro Phe Arg
                 260                 265                 270

 Ala Ala Asp Leu Leu Leu His Ser Lys Ala Ser Asn Leu Leu Leu
                 275                 280                 285

 Gly Phe Asp Arg Ser His Pro Asn Lys Gln Leu Trp Lys Ser Asp
                 290                 295                 300

 Asp Phe Gly Gln Thr Trp Ile Met Ile Gln Glu His Val Lys Ser
                 305                 310                 315

 Phe Ser Trp Gly Ile Asp Pro Tyr Asp Lys Pro Asn Thr Ile Tyr
                 320                 325                 330

 Ile Glu Arg His Glu Pro Ser Gly Tyr Ser Thr Val Phe Arg Ser
                 335                 340                 345

 Thr Asp Phe Phe Gln Ser Arg Glu Asn Gln Glu Val Ile Leu Glu
                 350                 355                 360

 Glu Val Arg Asp Phe Gln Leu Arg Asp Lys Tyr Met Phe Ala Thr
                 365                 370                 375

 Lys Val Val His Leu Leu Gly Ser Glu Gln Gln Ser Ser Val Gln
                 380                 385                 390

 Leu Trp Val Ser Phe Gly Arg Lys Pro Met Arg Ala Ala Gln Phe
                 395                 400                 405

 Val Thr Arg His Pro Ile Asn Glu Tyr Tyr Ile Ala Asp Ala Ser
                 410                 415                 420

 Glu Asp Gln Val Phe Val Cys Val Ser His Ser Asn Asn Arg Thr
                 425                 430                 435

 Asn Leu Tyr Ile Ser Glu Ala Glu Gly Leu Lys Phe Ser Leu Ser
                 440                 445                 450

 Leu Glu Asn Val Leu Tyr Tyr Ser Pro Gly Gly Ala Gly Ser Asp
                 455                 460                 465

 Thr Leu Val Arg Tyr Phe Ala Asn Glu Pro Phe Ala Asp Phe His
                 470                 475                 480

 Arg Val Glu Gly Leu Gln Gly Val Tyr Ile Ala Thr Leu Ile Asn
                 485                 490                 495

 Gly Ser Met Asn Glu Glu Asn Met Arg Ser Val Ile Thr Phe Asp
                 500                 505                 510

 Lys Gly Gly Thr Trp Glu Phe Leu Gln Ala Pro Ala Phe Thr Gly
                 515                 520                 525

 Tyr Gly Glu Lys Ile Asn Cys Glu Leu Ser Gln Gly Cys Ser Leu
                 530                 535                 540

 His Leu Ala Gln Arg Leu Ser Gln Leu Leu Asn Leu Gln Leu Arg
                 545                 550                 555

 Arg Met Pro Ile Leu Ser Lys Glu Ser Ala Pro Gly Leu Ile Ile
                 560                 565                 570

 Ala Thr Gly Ser Val Gly Lys Asn Leu Ala Ser Lys Thr Asn Val
                 575                 580                 585

 Tyr Ile Ser Ser Ser Ala Gly Ala Arg Trp Arg Glu Ala Leu Pro
                 590                 595                 600

 Gly Pro His Tyr Tyr Thr Trp Gly Asp His Gly Gly Ile Ile Thr
                 605                 610                 615

 Ala Ile Ala Gln Gly Met Glu Thr Asn Glu Leu Lys Tyr Ser Thr
                 620                 625                 630

 Asn Glu Gly Glu Thr Trp Lys Thr Phe Ile Phe Ser Glu Lys Pro
                 635                 640                 645

 Val Phe Val Tyr Gly Leu Leu Thr Glu Pro Gly Glu Lys Ser Thr
                 650                 655                 660

 Val Phe Thr Ile Phe Gly Ser Asn Lys Glu Asn Val His Ser Trp
                 665                 670                 675

 Leu Ile Leu Gln Val Asn Ala Thr Asp Ala Leu Gly Val Pro Cys
                 680                 685                 690

 Thr Glu Asn Asp Tyr Lys Leu Trp Ser Pro Ser Asp Glu Arg Gly
                 695                 700                 705

 Asn Glu Cys Leu Leu Gly His Lys Thr Val Phe Lys Arg Arg Thr
                 710                 715                 720

 Pro His Ala Thr Cys Phe Asn Gly Glu Asp Phe Asp Arg Pro Val
                 725                 730                 735

 Val Val Ser Asn Cys Ser Cys Thr Arg Glu Asp Tyr Glu Cys Asp
                 740                 745                 750

 Phe Gly Phe Lys Met Ser Glu Asp Leu Ser Leu Glu Val Cys Val
                 755                 760                 765

 Pro Asp Pro Glu Phe Ser Gly Lys Ser Tyr Ser Pro Pro Val Pro
                 770                 775                 780

 Cys Pro Val Gly Ser Thr Tyr Arg Arg Thr Arg Gly Tyr Arg Lys
                 785                 790                 795

 Ile Ser Gly Asp Thr Cys Ser Gly Gly Asp Val Glu Ala Arg Leu
                 800                 805                 810

 Glu Gly Glu Leu Val Pro Cys Pro Leu Ala Glu Glu Asn Glu Phe
                 815                 820                 825

 Ile Leu Tyr Ala Val Arg Lys Ser Ile Tyr Arg Tyr Asp Leu Ala
                 830                 835                 840

 Ser Gly Ala Thr Glu Gln Leu Pro Leu Thr Gly Leu Arg Ala Ala
                 845                 850                 855

 Val Ala Leu Asp Phe Asp Tyr Glu His Asn Cys Leu Tyr Trp Ser
                 860                 865                 870

 Asp Leu Ala Leu Asp Val Ile Gln Arg Leu Cys Leu Asn Gly Ser
                 875                 880                 885

 Thr Gly Gln Glu Val Ile Ile Asn Ser Gly Leu Glu Thr Val Glu
                 890                 895                 900

 Ala Leu Ala Phe Glu Pro Leu Ser Gln Leu Leu Tyr Trp Val Asp
                 905                 910                 915

 Ala Gly Phe Lys Lys Ile Glu Val Ala Asn Pro Asp Gly Asp Phe
                 920                 925                 930

 Arg Leu Thr Ile Val Asn Ser Ser Val Leu Asp Arg Pro Arg Ala
                 935                 940                 945

 Leu Val Leu Val Pro Gln Glu Gly Val Met Phe Trp Thr Asp Trp
                 950                 955                 960

 Gly Asp Leu Lys Pro Gly Ile Tyr Arg Ser Asn Met Asp Gly Ser
                 965                 970                 975

 Ala Ala Tyr His Leu Val Ser Glu Asp Val Lys Trp Pro Asn Gly
                 980                 985                 990

 Ile Ser Val Asp Asp Gln Trp Ile Tyr Trp Thr Asp Ala Tyr Leu
                 995                1000                1005

 Glu Cys Ile Glu Arg Ile Thr Phe Ser Gly Gln Gln Arg Ser Val
                1010                1015                1020

 Ile Leu Asp Asn Leu Pro His Pro Tyr Ala Ile Ala Val Phe Lys
                1025                1030                1035

 Asn Glu Ile Tyr Trp Asp Asp Trp Ser Gln Leu Ser Ile Phe Arg
                1040                1045                1050

 Ala Ser Lys Tyr Ser Gly Ser Gln Met Glu Ile Leu Ala Asn Gln
                1055                1060                1065

 Leu Thr Gly Leu Met Asp Met Lys Ile Phe Tyr Lys Gly Lys Asn
                1070                1075                1080

 Thr Gly Ser Asn Ala Cys Val Pro Arg Pro Cys Ser Leu Leu Cys
                1085                1090                1095

 Leu Pro Lys Ala Asn Asn Ser Arg Ser Cys Arg Cys Pro Glu Asp
                1100                1105                1110

 Val Ser Ser Ser Val Leu Pro Ser Gly Asp Leu Met Cys Asp Cys
                1115                1120                1125

 Pro Gln Gly Tyr Gln Leu Lys Asn Asn Thr Cys Val Lys Glu Glu
                1130                1135                1140

 Asn Thr Cys Leu Arg Asn Gln Tyr Arg Cys Ser Asn Gly Asn Cys
                1145                1150                1155

 Ile Asn Ser Ile Trp Trp Cys Asp Phe Asp Asn Asp Cys Gly Asp
                1160                1165                1170

 Met Ser Asp Glu Arg Asn Cys Pro Thr Thr Ile Cys Asp Leu Asp
                1175                1180                1185

 Thr Gln Phe Arg Cys Gln Glu Ser Gly Thr Cys Ile Pro Leu Ser
                1190                1195                1200

 Tyr Lys Cys Asp Leu Glu Asp Asp Cys Gly Asp Asn Ser Asp Glu
                1205                1210                1215

 Ser His Cys Glu Met His Gln Cys Arg Ser Asp Glu Tyr Asn Cys
                1220                1225                1230

 Ser Ser Gly Met Cys Ile Arg Ser Ser Trp Val Cys Asp Gly Asp
                1235                1240                1245

 Asn Asp Cys Arg Asp Trp Ser Asp Glu Ala Asn Cys Thr Ala Ile
                1250                1255                1260

 Tyr His Thr Cys Glu Ala Ser Asn Phe Gln Cys Arg Asn Gly His
                1265                1270                1275

 Cys Ile Pro Gln Arg Trp Ala Cys Asp Gly Asp Thr Asp Cys Gln
                1280                1285                1290

 Asp Gly Ser Asp Glu Asp Pro Val Asn Cys Glu Lys Lys Cys Asn
                1295                1300                1305

 Gly Phe Arg Cys Pro Asn Gly Thr Cys Ile Pro Ser Ser Lys His
                1310                1315                1320

 Cys Asp Gly Leu Arg Asp Cys Ser Asp Gly Ser Asp Glu Gln His
                1325                1330                1335

 Cys Glu Pro Leu Cys Thr His Phe Met Asp Phe Val Cys Lys Asn
                1340                1345                1350

 Arg Gln Gln Cys Leu Phe His Ser Met Val Cys Asp Gly Ile Ile
                1355                1360                1365

 Gln Cys Arg Asp Gly Ser Asp Glu Asp Ala Ala Phe Ala Gly Cys
                1370                1375                1380

 Ser Gln Asp Pro Glu Phe His Lys Val Cys Asp Glu Phe Gly Phe
                1385                1390                1395

 Gln Cys Gln Asn Gly Val Cys Ile Ser Leu Ile Trp Lys Cys Asp
                1400                1405                1410

 Gly Met Asp Asp Cys Gly Asp Tyr Ser Asp Glu Ala Asn Cys Glu
                1415                1420                1425

 Asn Pro Thr Glu Ala Pro Asn Cys Ser Arg Tyr Phe Gln Phe Arg
                1430                1435                1440

 Cys Glu Asn Gly His Cys Ile Pro Asn Arg Trp Lys Cys Asp Arg
                1445                1450                1455

 Glu Asn Asp Cys Gly Asp Trp Ser Asp Glu Lys Asp Cys Gly Asp
                1460                1465                1470

 Ser His Ile Leu Pro Phe Ser Thr Pro Gly Pro Ser Thr Cys Leu
                1475                1480                1485

 Pro Asn Tyr Tyr Arg Cys Ser Ser Gly Thr Cys Val Met Asp Thr
                1490                1495                1500

 Trp Val Cys Asp Gly Tyr Arg Asp Cys Ala Asp Gly Ser Asp Glu
                1505                1510                1515

 Glu Ala Cys Pro Leu Leu Ala Asn Val Thr Ala Ala Ser Thr Pro
                1520                1525                1530

 Thr Gln Leu Gly Arg Cys Asp Arg Phe Glu Phe Glu Cys His Gln
                1535                1540                1545

 Pro Lys Thr Cys Ile Pro Asn Trp Lys Arg Cys Asp Gly His Gln
                1550                1555                1560

 Asp Cys Gln Asp Gly Arg Asp Glu Ala Asn Cys Pro Thr His Ser
                1565                1570                1575

 Thr Leu Thr Cys Met Ser Arg Glu Phe Gln Cys Glu Asp Gly Glu
                1580                1585                1590

 Ala Cys Ile Val Leu Ser Glu Arg Cys Asp Gly Phe Leu Asp Cys
                1595                1600                1605

 Ser Asp Glu Ser Asp Glu Lys Ala Cys Ser Asp Glu Leu Thr Val
                1610                1615                1620

 Tyr Lys Val Gln Asn Leu Gln Trp Thr Ala Asp Phe Ser Gly Asp
                1625                1630                1635

 Val Thr Leu Thr Trp Met Arg Pro Lys Lys Met Pro Ser Ala Ser
                1640                1645                1650

 Cys Val Tyr Asn Val Tyr Tyr Arg Val Val Gly Glu Ser Ile Trp
                1655                1660                1665

 Lys Thr Leu Glu Thr His Ser Asn Lys Thr Asn Thr Val Leu Lys
                1670                1675                1680

 Val Leu Lys Pro Asp Thr Thr Tyr Gln Val Lys Val Gln Val Gln
                1685                1690                1695

 Cys Leu Ser Lys Ala His Asn Thr Asn Asp Phe Val Thr Leu Arg
                1700                1705                1710

 Thr Pro Glu Gly Leu Pro Asp Ala Pro Arg Asn Leu Gln Leu Ser
                1715                1720                1725

 Leu Pro Arg Glu Ala Glu Gly Val Ile Val Gly His Trp Ala Pro
                1730                1735                1740

 Pro Ile His Thr His Gly Leu Ile Arg Glu Tyr Ile Val Glu Tyr
                1745                1750                1755

 Ser Arg Ser Gly Ser Lys Met Trp Ala Ser Gln Arg Ala Ala Ser
                1760                1765                1770

 Asn Phe Thr Glu Ile Lys Asn Leu Leu Val Asn Thr Leu Tyr Thr
                1775                1780                1785

 Val Arg Val Ala Ala Val Thr Ser Arg Gly Ile Gly Asn Trp Ser
                1790                1795                1800

 Asp Ser Lys Ser Ile Thr Thr Ile Lys Gly Lys Val Ile Pro Pro
                1805                1810                1815

 Pro Asp Ile His Ile Asp Ser Tyr Gly Glu Asn Tyr Leu Ser Phe
                1820                1825                1830

 Thr Leu Thr Met Glu Ser Asp Ile Lys Val Asn Gly Tyr Val Val
                1835                1840                1845

 Asn Leu Phe Trp Ala Phe Asp Thr His Lys Gln Glu Arg Arg Thr
                1850                1855                1860

 Leu Asn Phe Arg Gly Ser Ile Leu Ser His Lys Val Gly Asn Leu
                1865                1870                1875

 Thr Ala His Thr Ser Tyr Glu Ile Ser Ala Trp Ala Lys Thr Asp
                1880                1885                1890

 Leu Gly Asp Ser Pro Leu Ala Phe Glu His Val Met Thr Arg Gly
                1895                1900                1905

 Val Arg Pro Pro Ala Pro Ser Leu Lys Ala Lys Ala Ile Asn Gln
                1910                1915                1920

 Thr Ala Val Glu Cys Thr Trp Thr Gly Pro Arg Asn Val Val Tyr
                1925                1930                1935

 Gly Ile Phe Tyr Ala Thr Ser Phe Leu Asp Leu Tyr Arg Asn Pro
                1940                1945                1950

 Lys Ser Leu Thr Thr Ser Leu His Asn Lys Thr Val Ile Val Ser
                1955                1960                1965

 Lys Asp Glu Gln Tyr Leu Phe Leu Val Arg Val Val Val Pro Tyr
                1970                1975                1980

 Gln Gly Pro Ser Ser Asp Tyr Val Val Val Lys Met Ile Pro Asp
                1985                1990                1995

 Ser Arg Leu Pro Pro Arg His Leu His Val Val His Thr Gly Lys
                2000                2005                2010

 Thr Ser Val Val Ile Lys Trp Glu Ser Pro Tyr Asp Ser Pro Asp
                2015                2020                2025

 Gln Asp Leu Leu Tyr Ala Ile Ala Val Lys Asp Leu Ile Arg Lys
                2030                2035                2040

 Thr Asp Arg Ser Tyr Lys Val Lys Ser Arg Asn Ser Thr Val Glu
                2045                2050                2055

 Tyr Thr Leu Asn Lys Leu Glu Pro Gly Gly Lys Tyr His Ile Ile
                2060                2065                2070

 Val Gln Leu Gly Asn Met Ser Lys Asp Ser Ser Ile Lys Ile Thr
                2075                2080                2085

 Thr Val Ser Leu Ser Ala Pro Asp Ala Leu Lys Ile Ile Thr Glu
                2090                2095                2100

 Asn Asp His Val Leu Leu Phe Trp Lys Ser Leu Ala Leu Lys Glu
                2105                2110                2115

 Lys His Phe Asn Glu Ser Arg Gly Tyr Glu Ile His Met Phe Asp
                2120                2125                2130

 Ser Ala Met Asn Ile Thr Ala Tyr Leu Gly Asn Thr Thr Asp Asn
                2135                2140                2145

 Phe Phe Lys Ile Ser Asn Leu Lys Met Gly His Asn Tyr Thr Phe
                2150                2155                2160

 Thr Val Gln Ala Arg Cys Leu Phe Gly Asn Gln Ile Cys Gly Glu
                2165                2170                2175

 Pro Ala Ile Leu Leu Tyr Asp Glu Leu Gly Ser Gly Ala Asp Ala
                2180                2185                2190

 Ser Ala Thr Gln Ala Ala Arg Ser Thr Asp Val Ala Ala Val Val
                2195                2200                2205

 Val Pro Ile Leu Phe Leu Ile Leu Leu Ser Leu Gly Val Gly Phe
                2210                2215                2220

 Ala Ile Leu Tyr Thr Lys His Arg Arg Leu Gln Ser Ser Phe Thr
                2225                2230                2235

 Ala Phe Ala Asn Ser His Tyr Ser Ser Arg Leu Gly Ser Ala Ile
                2240                2245                2250

 Phe Ser Ser Gly Asp Asp Leu Gly Glu Asp Asp Glu Asp Ala Pro
                2255                2260                2265

 Met Ile Thr Gly Phe Ser Asp Asp Val Pro Met Val Ile Ala
                2270                2275

<210> 2616
<211> 4735
<212> DNA
<213> Homo sapien

<400> 2616
 cggccccggc gccatgagtg gcggcggcgg cggagggggc tcggcgccca 50

 gtcgcttcgc cgactacttt gtcatctgcg gactggacac ggagaccggg 100

 ctggagccgg acgagctgtc ggcattatgc cagtacatac aggcttctaa 150

 agccagggat ggtgccagcc ctttcatttc aagtacgact gaaggagaaa 200

 attttgagca gacaccattg agaagaacat tcaaatctaa ggtccttgca 250

 cgatatcctg agaacgtaga atggaatccc tttgaccaag atgcagtagg 300

 aatgctatgt atgccgaaag ggctggcatt caagacccag gctgatccca 350

 gggagcccca attccatgcc tttattatca caagggagga tggctctcgg 400

 acatttgggt ttgccctcac attttatgaa gaggtgacta gcaagcagat 450

 ctgcagtgca atgcagaccc tctaccacat gcacaatgct gagtatgatg 500

 tcctacatgc tccccctgct gatgacagag accagagcag catggaggat 550

 ggtgaagaca ctcctgtgac caaactgcag cgcttcaact cctatgacat 600

 tagccgggac actctctacg tctctaagtg catctgcctc atcacaccca 650

 tgtctttcat gaaggcatgt cggagcgtgc tggagcaact ccaccaggca 700

 gtcacttcac ctcagccccc tccactgccc cttgagagct acatatacaa 750

 cgtactctac gaggtgccgc tcccacctcc tggccggtcc ttgaagtttt 800

 ctggggtcta tgggccaata atctgccaga gaccaagtac caatgagctt 850

 cccctatttg actttcctgt caaagaggtt tttgaactgc tcggggtgga 900

 gaatgtgttt cagcttttta cttgtgccct tctggagttt caaatcctgc 950

 tctactcaca gcattaccag agactgatga ctgtggcgga gacgattaca 1000

 gctctcatgt ttcctttcca gtggcagcat gtctatgtcc ctattctccc 1050

 agcttctctc ctgcatttct tagatgctcc tgttccatac ctgatgggtt 1100

 tgcattccaa tggcctggat gaccggtcaa agctggagct gcctcaagag 1150

 gctaacctct gctttgtgga cattgacaac cacttcattg agttgccaga 1200

 ggacttgcca cagttcccca acaaattgga gtttgtccag gaagtctctg 1250

 agattctcat ggcatttgga attccccctg aagggaatct tcattgcagt 1300

 gagagtgcct ccaagctgaa gaggctgcgg gcctctgagc ttgtctcgga 1350

 caagaggaat gggaacattg ctggctcccc tttgcattcc tacgagcttc 1400

 ttaaggagaa tgaaactatt gcccggctgc aagccttggt caagagaact 1450

 ggggtgagcc tggaaaagtt ggaagtgcgt gaagacccca gcagcaataa 1500

 ggatctcaaa gttcagtgtg atgaagaaga actcaggatt taccagctaa 1550

 acattcagat ccgggaagtt tttgcaaatc gtttcactca gatgtttgca 1600

 gattatgagg tgtttgtcat ccaacccagc caggataagg aatcctggtt 1650

 taccaacagg gagcaaatgc aaaactttga taaagcatct tttctgtcag 1700

 atcagcctga gccctacctg cccttcctct caagattcct ggagacccag 1750

 atgtttgcat ctttcattga caacaaaata atgtgtcatg atgatgatga 1800

 taaagaccct gtactccggg tatttgattc ccgagttgac aagatcaggc 1850

 tgttgaatgt tcggacacct actctccgta catccatgta ccagaagtgt 1900

 accactgtgg atgaagcaga gaaagcaatt gagctgcgtc tggcaaaaat 1950

 tgaccatact gcaattcacc cacatttact tgacatgaag attggacaag 2000

 ggaaatatga gccgggcttc ttccctaagc tgcagtctga tgtactttcc 2050

 actgggccag ccagcaacaa gtggacgaaa aggaatgccc ctgcccagtg 2100

 gaggcggaaa gatcggcaga agcagcacac agaacacctg cgtttagata 2150

 atgaccagag ggagaagtac atccaggaag ccaggactat gggcagcact 2200

 atccgccagc ccaaactgtc caacctctct ccatcagtga ttgcccagac 2250

 caattggaag tttgtagagg gcctgctgaa ggaatgccgc aataagacca 2300

 agaggatgct ggtggaaaag atgggccgag aagctgtgga gctagggcat 2350

 ggggaggtga acatcacagg ggtggaagag aacaccctga ttgccagcct 2400

 ttgtgatctc ctggaaagga tctggagtca tggactacaa gtgaaacagg 2450

 ggaaatcagc cttatggtcc cacctgttac attatcagga caaccggcag 2500

 agaaaactca catcaggaag cctcagtacc tcaggaatac ttcttgattc 2550

 agaacgtagg aagtctgatg ccagctcact catgcctccc ctgaggatct 2600

 ccctgattca ggatatgagg cacatccaga acatcgggga aatcaagact 2650

 gatgtgggaa aggccagagc atgggtgcga ctgtccatgg aaaaaaagtt 2700

 actttccaga cacctgaagc agctcctctc agaccatgag ctcaccaaaa 2750

 agttatataa gcgctatgcc ttcctgcgct gtgatgacga gaaggagcag 2800

 ttcctctatc acctcctgtc tttcaatgcc gtcgattact tttgcttcac 2850

 caatgtcttc acaactatcc tgatcccgta ccacattctg atcgtaccaa 2900

 gcaagaagct ggggggctcc atgttcactg ccaacccatg gatctgtata 2950

 tcaggagaat tgggtgagac acagatcatg cagattccca ggaatgtgct 3000

 agagatgacc ttcgagtgcc agaacttggg gaagcttact actgtccaga 3050

 ttggccatga taactctggg ctgtatgcca aatggctggt ggagtatgtg 3100

 atggtcagga atgagatcac aggacatacc tacaagttcc cgtgtggccg 3150

 gtggttaggg aagggcatgg atgatggaag cctggagcgg atcctagttg 3200

 gggagctgct cacatcccag cctgaggtgg atgagaggcc atgccggacc 3250

 ccgccgctgc agcagtcccc cagtgtcatc cggaggcttg ttaccatctc 3300

 acccaacaac aagcccaagc tgaacactgg gcagatccag gagtccatcg 3350

 gggaggcagt caatggcatt gtgaagcact tccataagcc tgagaaagag 3400

 cgaggcagtc tgacgctgtt gctctgtgga gagtgtggcc ttgtctcggc 3450

 cttggaacag gctttccagc atggatttaa atcgccccgg ctcttcaaaa 3500

 atgtcttcat ttgggatttc ctggaaaaag cacaaaccta ttatgagaca 3550

 ttagagaaga atgaagtagt ccctgaggaa aactggcata caagagcccg 3600

 gaacttctgc cgatttgtca ctgcaatcaa caatactccc cggaacatcg 3650

 gcaaggatgg caagtttcag atgctggtgt gcttgggagc cagagatcac 3700

 ctcctacacc actggattgc cctgctggct gactgcccca tcactgcaca 3750

 catgtatgag gatgtggcac tgatcaaaga ccatacactt gtcaattcct 3800

 tgattcgtgt gctgcagaca ttgcaggagt tcaacatcac gctggagacg 3850

 tcccttgtca agggcatcga catctgacct cccagcacca gccagcagca 3900

 ggactgagaa agactcaccc tgcagctctg accttttttc ccaaagggac 3950

 ttaagcgatt gtgcaggagt aggagacaaa atgtacactc actgtaaaaa 4000

 gaaaactaga ggatttttgg aataaataat ctattttaga gtttatttgc 4050

 tgatttgctt tttacacact ttcatgtgaa agagtgatag ggagagggag 4100

 cgaggctggt gccgcttatt ttgaagctgg tgccctccct cgccgtggcc 4150

 acatgctgga agcctgaggc ctccctggac tgagcctgtg gcactgcgtg 4200

 cgggacagtt atgtttcctt gccccgtcgc attaatgagg cccttccaca 4250

 tcatttttaa actaatgttt ttctatatta acattattat ggatatttgg 4300

 ctttcatagg ccacacacag gtgtgctgcg cgggaagccc catgctccaa 4350

 tcaaagggat ttttagtagt gcctctaagc aagcaccgat gagtcagtcc 4400

 cacgtatttt cttttttgtc agtattgttt gggaaggaga catgccggga 4450

 tgtgtcatcg tgccaaatac cacatttcct gttggcacag tttcacagaa 4500

 gtaaacataa gcatgtttta acaggttttt cttttctttt ttctttttta 4550

 aaatgtttta tttatttaac ccgccattgt gtgtttttaa gtattttctt 4600

 tttttaagga aaggaaaagc ttgtcacaat ctaactggct atgttattat 4650

 tattaaattt atgttttgca acttagaaac cagctacagt atggcccact 4700

 taataaaaca cctgaaacaa aaaaaaaaaa aaaaa 4735

<210> 2617
<211> 2396
<212> DNA
<213> Homo sapien

<400> 2617
 ggcacgaggg ctgtgcgggt ggcggccggc gcgcggtggg gcatggcggg 50

 ttcgcggggt gcggggcgca cggcggcgcc gagcgtgcgg ccggagaagc 100

 ggcggtctga gcccgaactg gagcctgagc ccgagccgga gccccccctc 150

 ctctgcacct ctcctctcag ccacagcacc ggcagcgatt ctggcgtctc 200

 cgacagcgag gagagtgtgt tctcaggcct ggaagattcc ggcagtgaca 250

 gcagtgagga tgatgacgaa ggcgacgagg agggagagga cggagccctt 300

 gatgacgagg gccacagtgg gattaaaaag accactgagg agcaggtgca 350

 ggccagcact ccttgcccga ggacagagat ggcgagcgcc cggattgggg 400

 atgagtatgc ggaggacagc tctgatgagg aggacatccg gaacacggtg 450

 ggcaacgtgc ccttggagtg gtacgatgac ttcccccacg tgggctacga 500

 cctggatggc aggcgcatct acaagcccct gcggacccgg gatgagctgg 550

 accagttcct ggacaagatg gacgatcctg actactggcg caccgtgcag 600

 gacccgatga cagggcggga cctgagactg acggatgagc aggtggccct 650

 ggtgcggcgg ctgcagagtg gccagtttgg ggatgtgggc ttcaacccct 700

 atgagccggc tgtcgacttc ttcagcgggg acgtcatgat ccacccggtg 750

 accaaccgcc cggccgacaa gcgcagcttc atcccctccc tggtggagaa 800

 ggagaaggtc tctcgcatgg tgcacgccat caagatgggc tggatccagc 850

 ctcgccggcc ccgagacccc acccccagct tctatgacct gtgggcccag 900

 gaggacccca acgccgtgct cgggcgccac aagatgcacg tacctgctcc 950

 caagctggcc ctgccaggcc acgccgagtc gtacaaccca ccccctgaat 1000

 acctgctcag cgaggaggag cgcttggcgt gggaacagca ggagccaggc 1050

 gagaggaagc tgagcttttt gccacgcaag ttcccgagcc tgcgggccgt 1100

 gcctgcctac ggacgcttca tccaggaacg cttcgagcgc tgccttgacc 1150

 tgtacctgtg cccacggcag cgcaagatga gggtgaatgt agaccctgag 1200

 gacctcatcc ccaagctgcc tcggccgagg gacctgcagc ccttccccac 1250

 gtgccaggcc ctggtctaca ggggccacag tgaccttgtc cggtgcctca 1300

 gtgtctctcc tgggggccag tggctggttt caggctctga cgacggctcc 1350

 ctgcggctct gggaggtggc cactgcccgc tgtgtgagga ctgttcccgt 1400

 ggggggcgtg gtgaagagtg tggcctggaa ccccagcccc gctgtctgcc 1450

 tggtggctgc agccgtggag gactcggtgc tgctgctgaa cccagctctg 1500

 ggggaccggc tggtggcggg cagcacagat cagctgttga gcgccttcgt 1550

 cccgcctgag gagcccccct tgcagccggc ccgctggctg gaggcctcag 1600

 aggaggagcg ccaagtgggc ctgcggctgc gcatctgcca cgggaagcca 1650

 gtgacgcagg tgacctggca cgggcgtggg gactacctgg ccgtggtgct 1700

 ggccacccaa ggccacaccc aggtgctgat tcaccagctg agccgtcgcc 1750

 gcagccagag tccgttccgc cgcagccacg gacaggtgca gcgagtggcc 1800

 ttccaccctg cccggccctt cctgttggtg gcgtcccagc gcagcgtccg 1850

 cctctaccac ctgctgcgcc aggagctcac caagaagctg atgcccaact 1900

 gcaagtgggt gtccagcctg gcggtgcacc ctgcaggtga caacgtcatc 1950

 tgtgggagct acgatagcaa gctggtgtgg tttgacctgg atctttccac 2000

 caagccatac aggatgctga gacaccacaa gaaggctctg cgggctgtgg 2050

 ccttccaccc gcggtaccca ctctttgcgt caggctcgga cgacggcagt 2100

 gtcatcgtct gccatggcat ggtgtacaat gaccttctgc agaacccctt 2150

 gctggtgccc gtcaaggtgc tgaagggaca cgtgctgacc cgagatctgg 2200

 gagtgctgga cgtcatcttc caccccaccc agccgtgggt cttctcctcg 2250

 ggggcagacg ggactgtccg cctcttcacc tagctgttct gcctgcctgg 2300

 ggctggggtg gtcgtgctga agtcaacaga gcctttaccc tgtgcaaaaa 2350

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 2396

<210> 2618
<211> 746
<212> PRT
<213> Homo sapien

<400> 2618
 Met Ala Gly Ser Arg Gly Ala Gly Arg Thr Ala Ala Pro Ser Val
   1               5                  10                  15

 Arg Pro Glu Lys Arg Arg Ser Glu Pro Glu Leu Glu Pro Glu Pro
                  20                  25                  30

 Glu Pro Glu Pro Pro Leu Leu Cys Thr Ser Pro Leu Ser His Ser
                  35                  40                  45

 Thr Gly Ser Asp Ser Gly Val Ser Asp Ser Glu Glu Ser Val Phe
                  50                  55                  60

 Ser Gly Leu Glu Asp Ser Gly Ser Asp Ser Ser Glu Asp Asp Asp
                  65                  70                  75

 Glu Gly Asp Glu Glu Gly Glu Asp Gly Ala Leu Asp Asp Glu Gly
                  80                  85                  90

 His Ser Gly Ile Lys Lys Thr Thr Glu Glu Gln Val Gln Ala Ser
                  95                 100                 105

 Thr Pro Cys Pro Arg Thr Glu Met Ala Ser Ala Arg Ile Gly Asp
                 110                 115                 120

 Glu Tyr Ala Glu Asp Ser Ser Asp Glu Glu Asp Ile Arg Asn Thr
                 125                 130                 135

 Val Gly Asn Val Pro Leu Glu Trp Tyr Asp Asp Phe Pro His Val
                 140                 145                 150

 Gly Tyr Asp Leu Asp Gly Arg Arg Ile Tyr Lys Pro Leu Arg Thr
                 155                 160                 165

 Arg Asp Glu Leu Asp Gln Phe Leu Asp Lys Met Asp Asp Pro Asp
                 170                 175                 180

 Tyr Trp Arg Thr Val Gln Asp Pro Met Thr Gly Arg Asp Leu Arg
                 185                 190                 195

 Leu Thr Asp Glu Gln Val Ala Leu Val Arg Arg Leu Gln Ser Gly
                 200                 205                 210

 Gln Phe Gly Asp Val Gly Phe Asn Pro Tyr Glu Pro Ala Val Asp
                 215                 220                 225

 Phe Phe Ser Gly Asp Val Met Ile His Pro Val Thr Asn Arg Pro
                 230                 235                 240

 Ala Asp Lys Arg Ser Phe Ile Pro Ser Leu Val Glu Lys Glu Lys
                 245                 250                 255

 Val Ser Arg Met Val His Ala Ile Lys Met Gly Trp Ile Gln Pro
                 260                 265                 270

 Arg Arg Pro Arg Asp Pro Thr Pro Ser Phe Tyr Asp Leu Trp Ala
                 275                 280                 285

 Gln Glu Asp Pro Asn Ala Val Leu Gly Arg His Lys Met His Val
                 290                 295                 300

 Pro Ala Pro Lys Leu Ala Leu Pro Gly His Ala Glu Ser Tyr Asn
                 305                 310                 315

 Pro Pro Pro Glu Tyr Leu Leu Ser Glu Glu Glu Arg Leu Ala Trp
                 320                 325                 330

 Glu Gln Gln Glu Pro Gly Glu Arg Lys Leu Ser Phe Leu Pro Arg
                 335                 340                 345

 Lys Phe Pro Ser Leu Arg Ala Val Pro Ala Tyr Gly Arg Phe Ile
                 350                 355                 360

 Gln Glu Arg Phe Glu Arg Cys Leu Asp Leu Tyr Leu Cys Pro Arg
                 365                 370                 375

 Gln Arg Lys Met Arg Val Asn Val Asp Pro Glu Asp Leu Ile Pro
                 380                 385                 390

 Lys Leu Pro Arg Pro Arg Asp Leu Gln Pro Phe Pro Thr Cys Gln
                 395                 400                 405

 Ala Leu Val Tyr Arg Gly His Ser Asp Leu Val Arg Cys Leu Ser
                 410                 415                 420

 Val Ser Pro Gly Gly Gln Trp Leu Val Ser Gly Ser Asp Asp Gly
                 425                 430                 435

 Ser Leu Arg Leu Trp Glu Val Ala Thr Ala Arg Cys Val Arg Thr
                 440                 445                 450

 Val Pro Val Gly Gly Val Val Lys Ser Val Ala Trp Asn Pro Ser
                 455                 460                 465

 Pro Ala Val Cys Leu Val Ala Ala Ala Val Glu Asp Ser Val Leu
                 470                 475                 480

 Leu Leu Asn Pro Ala Leu Gly Asp Arg Leu Val Ala Gly Ser Thr
                 485                 490                 495

 Asp Gln Leu Leu Ser Ala Phe Val Pro Pro Glu Glu Pro Pro Leu
                 500                 505                 510

 Gln Pro Ala Arg Trp Leu Glu Ala Ser Glu Glu Glu Arg Gln Val
                 515                 520                 525

 Gly Leu Arg Leu Arg Ile Cys His Gly Lys Pro Val Thr Gln Val
                 530                 535                 540

 Thr Trp His Gly Arg Gly Asp Tyr Leu Ala Val Val Leu Ala Thr
                 545                 550                 555

 Gln Gly His Thr Gln Val Leu Ile His Gln Leu Ser Arg Arg Arg
                 560                 565                 570

 Ser Gln Ser Pro Phe Arg Arg Ser His Gly Gln Val Gln Arg Val
                 575                 580                 585

 Ala Phe His Pro Ala Arg Pro Phe Leu Leu Val Ala Ser Gln Arg
                 590                 595                 600

 Ser Val Arg Leu Tyr His Leu Leu Arg Gln Glu Leu Thr Lys Lys
                 605                 610                 615

 Leu Met Pro Asn Cys Lys Trp Val Ser Ser Leu Ala Val His Pro
                 620                 625                 630

 Ala Gly Asp Asn Val Ile Cys Gly Ser Tyr Asp Ser Lys Leu Val
                 635                 640                 645

 Trp Phe Asp Leu Asp Leu Ser Thr Lys Pro Tyr Arg Met Leu Arg
                 650                 655                 660

 His His Lys Lys Ala Leu Arg Ala Val Ala Phe His Pro Arg Tyr
                 665                 670                 675

 Pro Leu Phe Ala Ser Gly Ser Asp Asp Gly Ser Val Ile Val Cys
                 680                 685                 690

 His Gly Met Val Tyr Asn Asp Leu Leu Gln Asn Pro Leu Leu Val
                 695                 700                 705

 Pro Val Lys Val Leu Lys Gly His Val Leu Thr Arg Asp Leu Gly
                 710                 715                 720

 Val Leu Asp Val Ile Phe His Pro Thr Gln Pro Trp Val Phe Ser
                 725                 730                 735

 Ser Gly Ala Asp Gly Thr Val Arg Leu Phe Thr
                 740                 745

<210> 2619
<211> 3321
<212> DNA
<213> Homo sapien

<400> 2619
 ttggacagcg tggggggttg gtggcactat gtggcgcgtc tgtgcgcgac 50

 gggctcagaa tgtagcccca tgggcgggac tcgaggctcg gtggacggcc 100

 ttgcaggagg tacccggaac tccacgagtg acctcgcgat ctggcccggc 150

 tcccgctcgt cgcaacagcg tgactacagg gtatggcggg gtccgggcac 200

 tgtgcggctg gacccccagt tctggggcca cgccgcggaa ccgcttactg 250

 ctgcagcttt tggggtcgcc cggccgccgc tattacagtc ttcccccgca 300

 tcagaaggtt ccattgcctt ctctttcccc cacaatgcag gcaggcacca 350

 tagcccgttg ggaaaaaaaa gagggggaca aaatcaatga aggtgaccta 400

 attgcagagg ttgaaactga taaagccact gttggatttg agagcctgga 450

 ggagtgttat atggcaaaga tacttgttgc tgaaggtacc agggatgttc 500

 ccatcggagc gatcatctgt atcacagttg gcaagcctga ggatattgag 550

 gcctttaaaa attatacact ggattcctca gcagcaccta ccccacaagc 600

 ggccccagca ccaacccctg ctgccactgc ttcgccacct acaccttctg 650

 ctcaggctcc tggtagctca tatccccctc acatgcaggt acttcttcct 700

 gccctctctc ccaccatgac catgggcaca gttcagagat gggaaaaaaa 750

 agtgggtgag aagctaagtg aaggagactt actggcagag atagaaactg 800

 acaaagccac tataggtttt gaagtacagg aagaaggtta tctggcaaaa 850

 atcctggtcc ctgaaggcac aagagatgtc cctctaggaa ccccactctg 900

 tatcattgta gaaaaagagg cagatatatc agcatttgct gactataggc 950

 caaccgaagt aacagattta aaaccacaag tgccaccacc taccccaccc 1000

 ccggtggccg ctgttcctcc aactccccag cctttagctc ctacaccttc 1050

 agcaccctgc ccagctactc ctgctggacc aaagggaagg gtgtttgtta 1100

 gccctcttgc aaagaagttg gcagtagaga aagggattga tcttacacaa 1150

 gtaaaaggga caggaccaga tggtagaatc accaagaagg atatcgactc 1200

 ttttgtgcct agtaaagttg ctcctgctcc ggcagctgtt gtgcctccca 1250

 caggtcctgg aatggcacca gttcctacag gtgtcttcac agatatccca 1300

 atcagcaaca ttcgtcgggt tattgcacag cgattaatgc aatcaaagca 1350

 aaccatacct cattattacc tttctatcga tgtaaatatg ggagaagttt 1400

 tgttggtacg gaaagaactt aataagatat tagaagggag aagcaaaatt 1450

 tctgtcaatg acttcatcat aaaagcttca gctttggcat gtttaaaagt 1500

 tcccgaagca aattcttctt ggatggacac agttataaga caaaatcatg 1550

 ttgttgatgt cagtgttgcg gtcagtactc ctgcaggact catcacacct 1600

 attgtgttta atgcacatat aaaaggagtg gaaaccattg ctaatgatgt 1650

 tgtttcttta gcaaccaaag caagagaggg taaactacag ccacatgaat 1700

 tccagggtgg cacttttacg atctccaatt taggaatgtt tggaattaag 1750

 aatttctctg ctattattaa cccacctcaa gcatgtattt tggcaattgg 1800

 tgcttcagag gataaactgg tccctgcaga taatgaaaaa gggtttgatg 1850

 tggctagcat gatgtctgtt acactcagtt gtgatcaccg ggtggtggat 1900

 ggagcagttg gagcccagtg gcttgctgag tttagaaagt accttgaaaa 1950

 acctatcact atgttgttgt aactaactca agaatttcta aactctccca 2000

 ggtcacactg attcattctt aacaagatat ttatatgtta ttaaacaggt 2050

 ggttcttttt attttaacca gttattttta ttattgagtc tgtccagata 2100

 agttatttat aatgggcatt actgaatttt taaaatgccg attacaccca 2150

 aatattgtgc acatttaata atcagacacc agatttttag ctctgtactc 2200

 ctaattaagg gacatgtatg tggccttgcc tagccctttg gtgataagta 2250

 cttcctctag gaaatgtacg ataggtagaa ttgtggttcc ctaaagacaa 2300

 gtacataaag gtgaccctga tgaaaccttg aagttctgaa atttaactgc 2350

 ctaaaatgtt ctccttagat gtgagagaaa gagaaatcag aaaaattaat 2400

 tctcttgggg gaagggcttg aattgaagct ttactttaga atttagccct 2450

 ggtttgaaat tttccattac atgatcttgg tttatcatcg atgggaaggg 2500

 tagaaaactt caaggaaaat aagtgaaatt ttaaaagtca gcattttctt 2550

 agacctcttc agctgattgt ttatttttct atgaattcct acacatggtt 2600

 attcccccct acttgagata atctaaatat aaaccagcta cttgatgtaa 2650

 ctgagaattt gtgtggatat ttatttaaac aaatgtgtaa ttttgagtac 2700

 agaattcaac agttacctcc aaaaaagaaa cattgttaat ataatttaac 2750

 agaagttgtg aaactaaaat tttctaagat taactggtag ttcattgtaa 2800

 atgaacataa tgaacagaat ttatgactcc actgtggaaa atgctatcaa 2850

 ataactaagg aatatatatg gaataagtgt acatatgtaa aatattgtta 2900

 ctagagttag atatgtgcca aagtccattt atcccaaatc ctgtctgaaa 2950

 aggaggggta cattggtaaa cattttggag tgcttaaaaa tgccaaaaac 3000

 aaaatggtaa tttctacttt gataaagtaa aaaagttaaa tgtgtgtaaa 3050

 aaagtgttct gtgtccttct actccagcat cgtctcatgt aaaataagaa 3100

 agccctaaaa tactattgga gagaaaaaat taactaggtt gctactttat 3150

 ttgcctaaat acttttttct attttgttag attttgcctt tcttttggaa 3200

 ggaaggaggc gatattctgg attataaaaa tgaattggga acattatcac 3250

 aattccagac tttctattaa tatttatgtg ttttaataaa cgtttgaaat 3300

 taaaaaaaaa aaaaaaaaaa a 3321

<210> 2620
<211> 647
<212> PRT
<213> Homo sapien

<400> 2620
 Met Trp Arg Val Cys Ala Arg Arg Ala Gln Asn Val Ala Pro Trp
   1               5                  10                  15

 Ala Gly Leu Glu Ala Arg Trp Thr Ala Leu Gln Glu Val Pro Gly
                  20                  25                  30

 Thr Pro Arg Val Thr Ser Arg Ser Gly Pro Ala Pro Ala Arg Arg
                  35                  40                  45

 Asn Ser Val Thr Thr Gly Tyr Gly Gly Val Arg Ala Leu Cys Gly
                  50                  55                  60

 Trp Thr Pro Ser Ser Gly Ala Thr Pro Arg Asn Arg Leu Leu Leu
                  65                  70                  75

 Gln Leu Leu Gly Ser Pro Gly Arg Arg Tyr Tyr Ser Leu Pro Pro
                  80                  85                  90

 His Gln Lys Val Pro Leu Pro Ser Leu Ser Pro Thr Met Gln Ala
                  95                 100                 105

 Gly Thr Ile Ala Arg Trp Glu Lys Lys Glu Gly Asp Lys Ile Asn
                 110                 115                 120

 Glu Gly Asp Leu Ile Ala Glu Val Glu Thr Asp Lys Ala Thr Val
                 125                 130                 135

 Gly Phe Glu Ser Leu Glu Glu Cys Tyr Met Ala Lys Ile Leu Val
                 140                 145                 150

 Ala Glu Gly Thr Arg Asp Val Pro Ile Gly Ala Ile Ile Cys Ile
                 155                 160                 165

 Thr Val Gly Lys Pro Glu Asp Ile Glu Ala Phe Lys Asn Tyr Thr
                 170                 175                 180

 Leu Asp Ser Ser Ala Ala Pro Thr Pro Gln Ala Ala Pro Ala Pro
                 185                 190                 195

 Thr Pro Ala Ala Thr Ala Ser Pro Pro Thr Pro Ser Ala Gln Ala
                 200                 205                 210

 Pro Gly Ser Ser Tyr Pro Pro His Met Gln Val Leu Leu Pro Ala
                 215                 220                 225

 Leu Ser Pro Thr Met Thr Met Gly Thr Val Gln Arg Trp Glu Lys
                 230                 235                 240

 Lys Val Gly Glu Lys Leu Ser Glu Gly Asp Leu Leu Ala Glu Ile
                 245                 250                 255

 Glu Thr Asp Lys Ala Thr Ile Gly Phe Glu Val Gln Glu Glu Gly
                 260                 265                 270

 Tyr Leu Ala Lys Ile Leu Val Pro Glu Gly Thr Arg Asp Val Pro
                 275                 280                 285

 Leu Gly Thr Pro Leu Cys Ile Ile Val Glu Lys Glu Ala Asp Ile
                 290                 295                 300

 Ser Ala Phe Ala Asp Tyr Arg Pro Thr Glu Val Thr Asp Leu Lys
                 305                 310                 315

 Pro Gln Val Pro Pro Pro Thr Pro Pro Pro Val Ala Ala Val Pro
                 320                 325                 330

 Pro Thr Pro Gln Pro Leu Ala Pro Thr Pro Ser Ala Pro Cys Pro
                 335                 340                 345

 Ala Thr Pro Ala Gly Pro Lys Gly Arg Val Phe Val Ser Pro Leu
                 350                 355                 360

 Ala Lys Lys Leu Ala Val Glu Lys Gly Ile Asp Leu Thr Gln Val
                 365                 370                 375

 Lys Gly Thr Gly Pro Asp Gly Arg Ile Thr Lys Lys Asp Ile Asp
                 380                 385                 390

 Ser Phe Val Pro Ser Lys Val Ala Pro Ala Pro Ala Ala Val Val
                 395                 400                 405

 Pro Pro Thr Gly Pro Gly Met Ala Pro Val Pro Thr Gly Val Phe
                 410                 415                 420

 Thr Asp Ile Pro Ile Ser Asn Ile Arg Arg Val Ile Ala Gln Arg
                 425                 430                 435

 Leu Met Gln Ser Lys Gln Thr Ile Pro His Tyr Tyr Leu Ser Ile
                 440                 445                 450

 Asp Val Asn Met Gly Glu Val Leu Leu Val Arg Lys Glu Leu Asn
                 455                 460                 465

 Lys Ile Leu Glu Gly Arg Ser Lys Ile Ser Val Asn Asp Phe Ile
                 470                 475                 480

 Ile Lys Ala Ser Ala Leu Ala Cys Leu Lys Val Pro Glu Ala Asn
                 485                 490                 495

 Ser Ser Trp Met Asp Thr Val Ile Arg Gln Asn His Val Val Asp
                 500                 505                 510

 Val Ser Val Ala Val Ser Thr Pro Ala Gly Leu Ile Thr Pro Ile
                 515                 520                 525

 Val Phe Asn Ala His Ile Lys Gly Val Glu Thr Ile Ala Asn Asp
                 530                 535                 540

 Val Val Ser Leu Ala Thr Lys Ala Arg Glu Gly Lys Leu Gln Pro
                 545                 550                 555

 His Glu Phe Gln Gly Gly Thr Phe Thr Ile Ser Asn Leu Gly Met
                 560                 565                 570

 Phe Gly Ile Lys Asn Phe Ser Ala Ile Ile Asn Pro Pro Gln Ala
                 575                 580                 585

 Cys Ile Leu Ala Ile Gly Ala Ser Glu Asp Lys Leu Val Pro Ala
                 590                 595                 600

 Asp Asn Glu Lys Gly Phe Asp Val Ala Ser Met Met Ser Val Thr
                 605                 610                 615

 Leu Ser Cys Asp His Arg Val Val Asp Gly Ala Val Gly Ala Gln
                 620                 625                 630

 Trp Leu Ala Glu Phe Arg Lys Tyr Leu Glu Lys Pro Ile Thr Met
                 635                 640                 645

 Leu Leu


<210> 2621
<211> 7239
<212> DNA
<213> Homo sapien

<400> 2621
 cactagaatg tgaaggatct tcgcggttct gggtgcccag aaaggcggcg 50

 acgcggcgga tgacaacatt aggccgcgac gcgctcctgg ccaggcggcg 100

 gctgtagtgt tagctttgga cgccgcagta gccgctgccg gtagcaagcc 150

 gactgaggga aggtgggggt ccgcccgggc tggtggacct cggggccgaa 200

 agttcccgcc ccgctcgggg gctgagccgg cagtgcctcc gcggccgctg 250

 ggcagcgccc ttcgtccagg ctcgcgcccc agctgccgcc gacgacagcg 300

 gccgagagaa gttggggtct gactagacgc ttacggggcc tcggaccccg 350

 gcgccgcggc gacctcggag gaaccggctc cttgcgtccc gcctccctgg 400

 gagctccgca cgggatttgc agatttacag aatggctgca cattaatgga 450

 aagagaagca taaacctatc ttctttcatt atggagggag gtttggcaga 500

 tggagaacct gatcgaactt cgcttcttgg tgatagcaaa gatgtccttg 550

 ggccatcaac tgttgtagca aacagtgacg aatctcagct tctgacacca 600

 ggaaagatga gtcagcgcca aggaaaagaa gcttatccaa cgccaaccaa 650

 agatttgcat cagccatctc ttagtccagc aagtcctcat agccagggtt 700

 ttgaaagagg gaaggaagat atttctcaaa ataaagatga atcttcactt 750

 tctatgtcaa agagcaagtc tgaatctaaa ctttataatg gctcagagaa 800

 ggacagttca acttcaagca aactcacaaa aaaagaatct cttaaggtac 850

 aaaagaaaaa ttaccgagaa gaaaagaaaa gagccacaaa ggagctgctc 900

 agtacaatca cagatccttc tgttattgtt atggctgatt ggttaaagat 950

 tcgtggtact ctaaagagct ggaccaagtt atggtgtgtg ttgaaacctg 1000

 gggtgctact gatctataaa acccaaaaaa atggtcagtg ggtaggaaca 1050

 gttcttctga atgcctgtga aatcattgaa cgtccatcaa aaaaggatgg 1100

 cttttgtttc aaacttttcc atcctttgga gcaatctatt tgggcagtga 1150

 agggtccaaa aggtgaagcg gttggatcca ttactcaacc cttacctagc 1200

 agttatttga tcatccgagc tacttcagag tcagatggaa ggtgctggat 1250

 ggatgctttg gagttggctt tgaaatgttc tagtcttctt aaacgtacaa 1300

 tgatcagaga aggaaaggaa catgacctga gcgtttcatc agatagcaca 1350

 catgtgactt tctatggctt actacgtgct aacaatctcc acagtggtga 1400

 taacttccag ttaaatgata gtgaaattga acgacaacat tttaaggacc 1450

 aagatatgta ttctgataaa tctgataaag aaaatgatca agaacatgat 1500

 gagtctgata atgaggtgat ggggaaaagt gaagaaagtg acacagatac 1550

 atcagaaaga caagatgact catatatcga acctgagcct gttgagcctt 1600

 taaaggagac tacctacact gaacagagcc atgaagaact tggagaggca 1650

 ggtgaggctt ctcaaacaga aactgtatct gaagaaaaca aaagccttat 1700

 ctggacacta ttgaaacaag tccgtcctgg catggaccta tccaaggtgg 1750

 ttctgcctac atttattttg gaaccccgtt ctttcctgga taaactttca 1800

 gattactact atcatgcaga tttcctatct gaggcagctc ttgaagaaaa 1850

 tccttatttc cgtttgaaga aagtagtgaa atggtatttg tcaggattct 1900

 ataaaaagcc aaagggactg aagaaacctt ataatcctat acttggcgag 1950

 actttccgtt gtttatggat tcatcccaga acaaacagca aaacttttta 2000

 tattgctgaa caggtgtccc atcatccacc aatatctgcc ttttatgtta 2050

 gtaatcgaaa agatggattt tgccttagcg gtagtatcct ggctaagtct 2100

 aagttttatg gaaactcatt atctgcaata ttagagggag aagcacggtt 2150

 aactttcttg aatagaggtg aagattatgt aatgacaatg ccatacgctc 2200

 attgtaaagg aattctttat ggtacaatga cactggagct tggtggaaca 2250

 gtcaatatta catgtcaaaa aactggatac agtgcaatac ttgaatttaa 2300

 actaaagcca ttcctaggga gtagtgactg tgttaatcaa atatcaggga 2350

 aacttaaact gggaaaagaa gtcctagcta ctttggaagg tcattgggat 2400

 agtgaagttt ttattactga taaaaagact gataattcag aggttttctg 2450

 gaatccaaca cctgacatta agcaatggag attaataagg cacactgtaa 2500

 aatttgaaga acagggagat tttgaatcag agaaactctg gcaacgggta 2550

 actcgagcca taaatgccaa agaccaaact gaagctaccc aagagaagta 2600

 tgttttggaa gaagctcaaa gacaagctgc cagggatcgg aaaacaaaaa 2650

 atgaagagtg gtcttgcaaa ttatttgaac ttgatccact cacaggagaa 2700

 tggcattaca agtttgcaga tacccgacca tgggacccac ttaatgatat 2750

 gatacagttt gaaaaagatg gtgttattca gaccaaagtg aaacatcgta 2800

 ctccaatggt tagcgtcccc aaaatgaaac ataagccaac caggcaacag 2850

 aagaaagtag caaaaggcta ttcctcccca gaacctgaca ttcaagactc 2900

 ctctggaagt gaagctcaat cagtaaaacc aagtacaaga agaaagaaag 2950

 gaatagaact gggagacatt cagagttcca tcgaatctat aaaacaaaca 3000

 caggaagaaa ttaaaagaaa tattatggct cttcgaaatc atttagtttc 3050

 aagcacaccg gccacggatt attttctgca acaaaaagac tacttcatca 3100

 ttttcctcct gattttgctt caagtcataa taaacttcat gttcaagtag 3150

 aagttctcta ccattgaatc agtgaactag aaagatctga tttggcctgg 3200

 gaccagtgtt caagttggtt tggtctttat taaaaatcac aatattccga 3250

 aaacaaaaaa acctaggaga taaatgtaga ggtattgact tttcgtatct 3300

 tttatcttca cactgaaaca agagctatcc tatttgatta ttaaagtgag 3350

 ctatgtgtta agtgccagga catttctagc ttttgtgaga atgtgtctac 3400

 atatgagtat aataaaccca catgtataca caattgtctc ttatgtactc 3450

 ctacctgaca gtagtctttg tattctatag tatgttctga gatataatgt 3500

 taacattgtt cataacaaaa aatgctatca atcttataaa tatatgtaat 3550

 ctattttctt cataaaacag gcacaaaagt tttatcagta aggaattaca 3600

 gattgagaaa tgatggaata atagacataa ttaattcaat acactactgt 3650

 taaaatcatt tgcaaagcac tcagctcaat tatcttctta gaaagaaaga 3700

 aaaagtatga atggtcaaaa tgaatacatc gagagagata aatggcaaat 3750

 tgctttttta aaagtttaca taagtttttt ttaaccccta gaatttaata 3800

 tttgtagatg caggtaaata tatatactta cgtgtatatc agtataaaaa 3850

 cactggtgtg caattaattg gattgattat aataccacct taagcacttg 3900

 ctgaaaaaag tgtggtcaaa attgattgct gtccttttgt cttatttttg 3950

 tttttcttaa gtcagctggt tcataacata ggccaaattc tagagatgtt 4000

 tatagagcat ttgaagtgct gataatttat gttttttcat tatgaaaact 4050

 tattttagct ttagactcca gtgtgttcag tgaataagta gaatataaaa 4100

 aaatataacc agtattttac ttcaaaagcc aaaaagaggc aataagaaaa 4150

 gacactttgt ggtggccttt atgtgtgcat taaaattggt ttctgtaaaa 4200

 cgtgtaataa gttgagtatc tacgaagagt atcaagttct gaagtttaat 4250

 ttttttatta tcctcctctc ttcttagtaa cttctttctg tggcaaaacc 4300

 acaattcttt aagattccta ttgttcaggc taaggcaaat ttttttgttt 4350

 gtttcttcag tttaatattt tgattttgtg tttttacgta aatatttata 4400

 ttccttgaaa gcaatttttg ccaaggtagt tcagtttagg aatatgttgt 4450

 tctaaaatat gtcttagaat cctgaaagca tagattttga aatgtttttt 4500

 taatgaaaat gaaggtcaga gagaataatt gccctgacca catttgcctt 4550

 tcagtaggag gaggctgtga aatagtaaaa ttataatcgt ttatgccatg 4600

 ataaatacaa gattggtaaa taaatacatt gattggtaaa ttatgagaat 4650

 caaaatgata aaaagagcct gcttttttcc ctaaccaata tagctatctt 4700

 aagtatcctt aggtttctgt gaagaaccat ttcccatgtt ttcttggcaa 4750

 aataatgctg tattccatat gtacatgtga aatgatgttt taaattgata 4800

 aaagcttaaa taagatctac ctatacccag tattttcatg atattagaac 4850

 aaatgggttt ttggttatat tttatatttg tcaatataat ttttgtattc 4900

 acattctgtt acactctgcc tattcattga tatatgatat tctgtaaata 4950

 ttgtacaatt tgatcttttt tatggtttaa attagttaat tacatacaaa 5000

 ttgattggct tatcacaaaa atcatttcat cagtaaacct tgttaacatt 5050

 ttgtactggt gacccacctc ttaggacttt ggtcttatcc acgtgtatgt 5100

 tgttttcatt tggtccaaat aatattttat ttgtatgggt atcttctaag 5150

 actaaatagg tagttgtgtt ctttattttt aaaatttctt tttagagcaa 5200

 atgttatggg ttcttaccca aagagtcaaa aactatttct taagaaagag 5250

 cagagttatt catgactgtt ctttatacac taaaagcatg catctaatct 5300

 aatagtcctc ttattatgct tttagttgta tgagtctctt tctatgaact 5350

 gaacacaaaa ctcaggaatt ggtggcttaa ttttagatca gtgcttgtac 5400

 taggcttagt tatatgaatc tttataacac ataattacta actttgtagc 5450

 catatatgta attgactttg aatgttattt acctgaaatt aatcttcctt 5500

 cacacatgga ccgtaaacgg ttcccagttg tctgagagcc tcatgagggt 5550

 ttctaggatt tatgacctta tgaccagttt ttttcattta ccaagatttt 5600

 attttcctac atgaaaattt aattgagtaa taattattca catgtgcatt 5650

 ttctttttag ctgttaaatg tactatgcca tcatccacca tttagtaaaa 5700

 tgtagctggc ccaggacatg taaaaaaaaa aaaaaaacaa caacaataaa 5750

 tagggcatgt gaaatgttaa gttacagcaa tagatatttt atttgtattt 5800

 catgttagta cttttttgtt ttatatcact tataaaggta cagtgtactc 5850

 tttgtcacag ctcagttggt aaccgcattc cattgaaaag ttggccttgt 5900

 aaaatacaac tctcatttaa tattcatgct tttgtgcctt taagaaaata 5950

 ttttttgtca ttttttgtgt tacagaacta taatgtgatt caaggtgttt 6000

 ataggcttgt cataaaaggg tcatttctgt gtgttacttt ctttttatat 6050

 agctatagta tatttaaaca ataatactat cttttatagg ggtttgtcta 6100

 tttacctatt ctttactcag acattgatgt agacttgtca gattattctg 6150

 agtattgtta acagtgcctt ttcgatggaa tcacactttt tggctgtcac 6200

 cttgtgccat atacacacaa aattttgtgg aaggcagttt taactttctg 6250

 aagaatatct gtcaaaattt aagaaaacaa atgtataaaa ttccattttt 6300

 tccagtgttt agcatttcta gtaagcagtg aggttgtttg acatacagtg 6350

 atgatggcat tattgataag ccatacatga gactgcagat tatattgaat 6400

 catattaaat gtacagaaat aaaatattag atttatatca aattttccaa 6450

 tttgaaccag tggggaaaat cccacagaaa tcagtaagtt tacatttcaa 6500

 tttctatctt atttgactaa gtggaaagag attctttaaa atgtataacc 6550

 tgccattatg taatttggtt tcattttatt ctacctgttg tgtgagttta 6600

 gtatatttaa tttacttttt gttactcttt acatactgtt tatttttgtt 6650

 agtttttaat tgaagatgga ctgttgaaat tgtataggac cagtgtctta 6700

 ttaatatgat taatatattt agaagagcca cgtgaaaccc atgacaaaat 6750

 gaatgtgaat attctttcta aaaatttaga aaatgttatc tttttgcatt 6800

 tattatgtaa aactgtttta cagtatcaaa atttttcact taaagaaaaa 6850

 aaatgccatg aaacatttga actgatgagc cacagaactt cagttgaaat 6900

 ttttttcact ttttagcatg ctaaatatac atctgagttt aaatgttctg 6950

 tttaatggcc attcataaat tcaagcacta ccactggtca gttttgtgtg 7000

 atagaataaa aatatgttac ctgcagtgta agtacagcac actgtcaaat 7050

 tcttttcctt aaggtgcaca gtaaatgtac agatagttat aggccactgt 7100

 tttgtaatgt agtacatttc taatctatta ttcctaacct attataactg 7150

 tttgcagaaa gaaaagaatt tttctaataa tctgtaaaat tatgctaact 7200

 tctacaagta ggcttctaaa taaaattttt aaaaagagc 7239

<210> 2622
<211> 889
<212> PRT
<213> Homo sapien

<400> 2622
 Met Glu Gly Gly Leu Ala Asp Gly Glu Pro Asp Arg Thr Ser Leu
   1               5                  10                  15

 Leu Gly Asp Ser Lys Asp Val Leu Gly Pro Ser Thr Val Val Ala
                  20                  25                  30

 Asn Ser Asp Glu Ser Gln Leu Leu Thr Pro Gly Lys Met Ser Gln
                  35                  40                  45

 Arg Gln Gly Lys Glu Ala Tyr Pro Thr Pro Thr Lys Asp Leu His
                  50                  55                  60

 Gln Pro Ser Leu Ser Pro Ala Ser Pro His Ser Gln Gly Phe Glu
                  65                  70                  75

 Arg Gly Lys Glu Asp Ile Ser Gln Asn Lys Asp Glu Ser Ser Leu
                  80                  85                  90

 Ser Met Ser Lys Ser Lys Ser Glu Ser Lys Leu Tyr Asn Gly Ser
                  95                 100                 105

 Glu Lys Asp Ser Ser Thr Ser Ser Lys Leu Thr Lys Lys Glu Ser
                 110                 115                 120

 Leu Lys Val Gln Lys Lys Asn Tyr Arg Glu Glu Lys Lys Arg Ala
                 125                 130                 135

 Thr Lys Glu Leu Leu Ser Thr Ile Thr Asp Pro Ser Val Ile Val
                 140                 145                 150

 Met Ala Asp Trp Leu Lys Ile Arg Gly Thr Leu Lys Ser Trp Thr
                 155                 160                 165

 Lys Leu Trp Cys Val Leu Lys Pro Gly Val Leu Leu Ile Tyr Lys
                 170                 175                 180

 Thr Gln Lys Asn Gly Gln Trp Val Gly Thr Val Leu Leu Asn Ala
                 185                 190                 195

 Cys Glu Ile Ile Glu Arg Pro Ser Lys Lys Asp Gly Phe Cys Phe
                 200                 205                 210

 Lys Leu Phe His Pro Leu Glu Gln Ser Ile Trp Ala Val Lys Gly
                 215                 220                 225

 Pro Lys Gly Glu Ala Val Gly Ser Ile Thr Gln Pro Leu Pro Ser
                 230                 235                 240

 Ser Tyr Leu Ile Ile Arg Ala Thr Ser Glu Ser Asp Gly Arg Cys
                 245                 250                 255

 Trp Met Asp Ala Leu Glu Leu Ala Leu Lys Cys Ser Ser Leu Leu
                 260                 265                 270

 Lys Arg Thr Met Ile Arg Glu Gly Lys Glu His Asp Leu Ser Val
                 275                 280                 285

 Ser Ser Asp Ser Thr His Val Thr Phe Tyr Gly Leu Leu Arg Ala
                 290                 295                 300

 Asn Asn Leu His Ser Gly Asp Asn Phe Gln Leu Asn Asp Ser Glu
                 305                 310                 315

 Ile Glu Arg Gln His Phe Lys Asp Gln Asp Met Tyr Ser Asp Lys
                 320                 325                 330

 Ser Asp Lys Glu Asn Asp Gln Glu His Asp Glu Ser Asp Asn Glu
                 335                 340                 345

 Val Met Gly Lys Ser Glu Glu Ser Asp Thr Asp Thr Ser Glu Arg
                 350                 355                 360

 Gln Asp Asp Ser Tyr Ile Glu Pro Glu Pro Val Glu Pro Leu Lys
                 365                 370                 375

 Glu Thr Thr Tyr Thr Glu Gln Ser His Glu Glu Leu Gly Glu Ala
                 380                 385                 390

 Gly Glu Ala Ser Gln Thr Glu Thr Val Ser Glu Glu Asn Lys Ser
                 395                 400                 405

 Leu Ile Trp Thr Leu Leu Lys Gln Val Arg Pro Gly Met Asp Leu
                 410                 415                 420

 Ser Lys Val Val Leu Pro Thr Phe Ile Leu Glu Pro Arg Ser Phe
                 425                 430                 435

 Leu Asp Lys Leu Ser Asp Tyr Tyr Tyr His Ala Asp Phe Leu Ser
                 440                 445                 450

 Glu Ala Ala Leu Glu Glu Asn Pro Tyr Phe Arg Leu Lys Lys Val
                 455                 460                 465

 Val Lys Trp Tyr Leu Ser Gly Phe Tyr Lys Lys Pro Lys Gly Leu
                 470                 475                 480

 Lys Lys Pro Tyr Asn Pro Ile Leu Gly Glu Thr Phe Arg Cys Leu
                 485                 490                 495

 Trp Ile His Pro Arg Thr Asn Ser Lys Thr Phe Tyr Ile Ala Glu
                 500                 505                 510

 Gln Val Ser His His Pro Pro Ile Ser Ala Phe Tyr Val Ser Asn
                 515                 520                 525

 Arg Lys Asp Gly Phe Cys Leu Ser Gly Ser Ile Leu Ala Lys Ser
                 530                 535                 540

 Lys Phe Tyr Gly Asn Ser Leu Ser Ala Ile Leu Glu Gly Glu Ala
                 545                 550                 555

 Arg Leu Thr Phe Leu Asn Arg Gly Glu Asp Tyr Val Met Thr Met
                 560                 565                 570

 Pro Tyr Ala His Cys Lys Gly Ile Leu Tyr Gly Thr Met Thr Leu
                 575                 580                 585

 Glu Leu Gly Gly Thr Val Asn Ile Thr Cys Gln Lys Thr Gly Tyr
                 590                 595                 600

 Ser Ala Ile Leu Glu Phe Lys Leu Lys Pro Phe Leu Gly Ser Ser
                 605                 610                 615

 Asp Cys Val Asn Gln Ile Ser Gly Lys Leu Lys Leu Gly Lys Glu
                 620                 625                 630

 Val Leu Ala Thr Leu Glu Gly His Trp Asp Ser Glu Val Phe Ile
                 635                 640                 645

 Thr Asp Lys Lys Thr Asp Asn Ser Glu Val Phe Trp Asn Pro Thr
                 650                 655                 660

 Pro Asp Ile Lys Gln Trp Arg Leu Ile Arg His Thr Val Lys Phe
                 665                 670                 675

 Glu Glu Gln Gly Asp Phe Glu Ser Glu Lys Leu Trp Gln Arg Val
                 680                 685                 690

 Thr Arg Ala Ile Asn Ala Lys Asp Gln Thr Glu Ala Thr Gln Glu
                 695                 700                 705

 Lys Tyr Val Leu Glu Glu Ala Gln Arg Gln Ala Ala Arg Asp Arg
                 710                 715                 720

 Lys Thr Lys Asn Glu Glu Trp Ser Cys Lys Leu Phe Glu Leu Asp
                 725                 730                 735

 Pro Leu Thr Gly Glu Trp His Tyr Lys Phe Ala Asp Thr Arg Pro
                 740                 745                 750

 Trp Asp Pro Leu Asn Asp Met Ile Gln Phe Glu Lys Asp Gly Val
                 755                 760                 765

 Ile Gln Thr Lys Val Lys His Arg Thr Pro Met Val Ser Val Pro
                 770                 775                 780

 Lys Met Lys His Lys Pro Thr Arg Gln Gln Lys Lys Val Ala Lys
                 785                 790                 795

 Gly Tyr Ser Ser Pro Glu Pro Asp Ile Gln Asp Ser Ser Gly Ser
                 800                 805                 810

 Glu Ala Gln Ser Val Lys Pro Ser Thr Arg Arg Lys Lys Gly Ile
                 815                 820                 825

 Glu Leu Gly Asp Ile Gln Ser Ser Ile Glu Ser Ile Lys Gln Thr
                 830                 835                 840

 Gln Glu Glu Ile Lys Arg Asn Ile Met Ala Leu Arg Asn His Leu
                 845                 850                 855

 Val Ser Ser Thr Pro Ala Thr Asp Tyr Phe Leu Gln Gln Lys Asp
                 860                 865                 870

 Tyr Phe Ile Ile Phe Leu Leu Ile Leu Leu Gln Val Ile Ile Asn
                 875                 880                 885

 Phe Met Phe Lys


<210> 2623
<211> 5026
<212> DNA
<213> Homo sapien

<400> 2623
 agaggaggaa attgttcctc gtctgataag acaacagtgg agaaaggacg 50

 catgctgttt cttagggaca cggctgactt ccagatatga ccatgtattt 100

 gtggcttaaa ctcttggcat ttggctttgc ctttctggac acagaagtat 150

 ttgtgacagg gcaaagccca acaccttccc ccactggatt gactacagca 200

 aagatgccca gtgttccact ttcaagtgac cccttaccta ctcacaccac 250

 tgcattctca cccgcaagca cctttgaaag agaaaatgac ttctcagaga 300

 ccacaacttc tcttagtcca gacaatactt ccacccaagt atccccggac 350

 tctttggata atgctagtgc ttttaatacc acaggtgttt catcagtaca 400

 gacgcctcac cttcccacgc acgcagactc gcagacgccc tctgctggaa 450

 ctgacacgca gacattcagc ggctccgccg ccaatgcaaa actcaaccct 500

 accccaggca gcaatgctat ctcagatgtc ccaggagaga ggagtacagc 550

 cagcaccttt cctacagacc cagtttcccc attgacaacc accctcagcc 600

 ttgcacacca cagctctgct gccttacctg cacgcacctc caacaccacc 650

 atcacagcga acacctcaga tgcctacctt aatgcctctg aaacaaccac 700

 tctgagccct tctggaagcg ctgtcatttc aaccacaaca atagctacta 750

 ctccatctaa gccaacatgt gatgaaaaat atgcaaacat cactgtggat 800

 tacttatata acaaggaaac taaattattt acagcaaagc taaatgttaa 850

 tgagaatgtg gaatgtggaa acaatacttg cacaaacaat gaggtgcata 900

 accttacaga atgtaaaaat gcgtctgttt ccatatctca taattcatgt 950

 actgctcctg ataagacatt aatattagat gtgccaccag gggttgaaaa 1000

 gtttcagtta catgattgta cacaagttga aaaagcagat actactattt 1050

 gtttaaaatg gaaaaatatt gaaaccttta cttgtgatac acagaatatt 1100

 acctacagat ttcagtgtgg taatatgata tttgataata aagaaattaa 1150

 attagaaaac cttgaacccg aacatgagta taagtgtgac tcagaaatac 1200

 tctataataa ccacaagttt actaacgcaa gtaaaattat taaaacagat 1250

 tttgggagtc caggagagcc tcagattatt ttttgtagaa gtgaagctgc 1300

 acatcaagga gtaattacct ggaatccccc tcaaagatca tttcataatt 1350

 ttaccctctg ttatataaaa gagacagaaa aagattgcct caatctggat 1400

 aaaaacctga tcaaatatga tttgcaaaat ttaaaacctt atacgaaata 1450

 tgttttatca ttacatgcct acatcattgc aaaagtgcaa cgtaatggaa 1500

 gtgctgcaat gtgtcatttc acaactaaaa gtgctcctcc aagccaggtc 1550

 tggaacatga ctgtctccat gacatcagat aatagtatgc atgtcaagtg 1600

 taggcctccc agggaccgta atggccccca tgaacgttac catttggaag 1650

 ttgaagctgg aaatactctg gttagaaatg agtcgcataa gaattgcgat 1700

 ttccgtgtaa aagatcttca atattcaaca gactacactt ttaaggccta 1750

 ttttcacaat ggagactatc ctggagaacc ctttatttta catcattcaa 1800

 catcttataa ttctaaggca ctgatagcat ttctggcatt tctgattatt 1850

 gtgacatcaa tagccctgct tgttgttctc tacaaaatct atgatctaca 1900

 taagaaaaga tcctgcaatt tagatgaaca gcaggagctt gttgaaaggg 1950

 atgatgaaaa acaactgatg aatgtggagc caatccatgc agatattttg 2000

 ttggaaactt ataagaggaa gattgctgat gaaggaagac tttttctggc 2050

 tgaatttcag agcatcccgc gggtgttcag caagtttcct ataaaggaag 2100

 ctcgaaagcc ctttaaccag aataaaaacc gttatgttga cattcttcct 2150

 tatgattata accgtgttga actctctgag ataaacggag atgcagggtc 2200

 aaactacata aatgccagct atattgatgg tttcaaagaa cccaggaaat 2250

 acattgctgc acaaggtccc agggatgaaa ctgttgatga tttctggagg 2300

 atgatttggg aacagaaagc cacagttatt gtcatggtca ctcgatgtga 2350

 agaaggaaac aggaacaagt gtgcagaata ctggccgtca atggaagagg 2400

 gcactcgggc ttttggagat gttgttgtaa agatcaacca gcacaaaaga 2450

 tgtccagatt acatcattca gaaattgaac attgtaaata aaaaagaaaa 2500

 agcaactgga agagaggtga ctcacattca gttcaccagc tggccagacc 2550

 acggggtgcc tgaggatcct cacttgctcc tcaaactgag aaggagagtg 2600

 aatgccttca gcaatttctt cagtggtccc attgtggtgc actgcagtgc 2650

 tggtgttggg cgcacaggaa cctatatcgg aattgatgcc atgctagaag 2700

 gcctggaagc cgagaacaaa gtggatgttt atggttatgt tgtcaagcta 2750

 aggcgacaga gatgcctgat ggttcaagta gaggcccagt acatcttgat 2800

 ccatcaggct ttggtggaat acaatcagtt tggagaaaca gaagtgaatt 2850

 tgtctgaatt acatccatat ctacataaca tgaagaaaag ggatccaccc 2900

 agtgagccgt ctccactaga ggctgaattc cagagacttc cttcatatag 2950

 gagctggagg acacagcaca ttggaaatca agaagaaaat aaaagtaaaa 3000

 acaggaattc taatgtcatc ccatatgact ataacagagt gccacttaaa 3050

 catgagctgg aaatgagtaa agagagtgag catgattcag atgaatcctc 3100

 tgatgatgac agtgattcag aggaaccaag caaatacatc aatgcatctt 3150

 ttataatgag ctactggaaa cctgaagtga tgattgctgc tcagggacca 3200

 ctgaaggaga ccattggtga cttttggcag atgatcttcc aaagaaaagt 3250

 caaagttatt gttatgctga cagaactgaa acatggagac caggaaatct 3300

 gtgctcagta ctggggagaa ggaaagcaaa catatggaga tattgaagtt 3350

 gacctgaaag acacagacaa atcttcaact tatacccttc gtgtctttga 3400

 actgagacat tccaagagga aagactctcg aactgtgtac cagtaccaat 3450

 atacaaactg gagtgtggag cagcttcctg cagaacccaa ggaattaatc 3500

 tctatgattc aggtcgtcaa acaaaaactt ccccagaaga attcctctga 3550

 agggaacaag catcacaaga gtacacctct actcattcac tgcagggatg 3600

 gatctcagca aacgggaata ttttgtgctt tgttaaatct cttagaaagt 3650

 gcggaaacag aagaggtagt ggatattttt caagtggtaa aagctctacg 3700

 caaagctagg ccaggcatgg tttccacatt cgagcaatat caattcctat 3750

 atgacgtcat tgccagcacc taccctgctc agaatggaca agtaaagaaa 3800

 aacaaccatc aagaagataa aattgaattt gataatgaag tggacaaagt 3850

 aaagcaggat gctaattgtg ttaatccact tggtgcccca gaaaagctcc 3900

 ctgaagcaaa ggaacaggct gaaggttctg aacccacgag tggcactgag 3950

 gggccagaac attctgtcaa tggtcctgca agtccagctt taaatcaagg 4000

 ttcataggaa aagacataaa tgaggaaact ccaaacctcc tgttagctgt 4050

 tatttctatt tttgtagaag taggaagtga aaataggtat acagtggatt 4100

 aattaaatgc agcgaaccaa tatttgtaga agggttatat tttactactg 4150

 tggaaaaata tttaagatag ttttgccaga acagtttgta cagacgtatg 4200

 cttattttaa aattttatct cttattcagt aaaaaacaac ttctttgtaa 4250

 tcgttatgtg tgtatatgta tgtgtgtatg ggtgtgtgtt tgtgtgagag 4300

 acagagaaag agagagaatt ctttcaagtg aatctaaaag cttttgcttt 4350

 tcctttgttt ttatgaagaa aaaatacatt ttatattaga agtgttaact 4400

 tagcttgaag gatctgtttt taaaaatcat aaactgtgtg cagactcaat 4450

 aaaatcatgt acatttctga aatgacctca agatgtcctc cttgttctac 4500

 tcatatatat ctatcttata tacttactat tttacttcta gagatagtac 4550

 ataaaggtgg tatgtgtgtg tatgctacta caaaaaagtt gttaactaaa 4600

 ttaacattgg gaaatcttat attccatata ttagcattta gtccaatgtc 4650

 tttttaagct tatttaatta aaaaatttcc agtgagctta tcatgctgtc 4700

 tttacatggg gttttcaatt ttgcatgctc gattattccc tgtacaatat 4750

 ttaaaattta ttgcttgata cttttgacaa caaattaggt tttgtacaat 4800

 tgaacttaaa taaatgtcat taaaataaat aaatgcaata tgtattaata 4850

 ttcattgtat aaaaatagaa gaatacaaac atatttgtta aatatttaca 4900

 tatgaaattt aatatagcta tttttatgga atttttcatt gatatgaaaa 4950

 atatgatatt gcatatgcat agttcccatg ttaaatccca ttcataactt 5000

 tcattaaagc atttactttg aatttc 5026

<210> 2624
<211> 1304
<212> PRT
<213> Homo sapien

<400> 2624
 Met Tyr Leu Trp Leu Lys Leu Leu Ala Phe Gly Phe Ala Phe Leu
   1               5                  10                  15

 Asp Thr Glu Val Phe Val Thr Gly Gln Ser Pro Thr Pro Ser Pro
                  20                  25                  30

 Thr Gly Leu Thr Thr Ala Lys Met Pro Ser Val Pro Leu Ser Ser
                  35                  40                  45

 Asp Pro Leu Pro Thr His Thr Thr Ala Phe Ser Pro Ala Ser Thr
                  50                  55                  60

 Phe Glu Arg Glu Asn Asp Phe Ser Glu Thr Thr Thr Ser Leu Ser
                  65                  70                  75

 Pro Asp Asn Thr Ser Thr Gln Val Ser Pro Asp Ser Leu Asp Asn
                  80                  85                  90

 Ala Ser Ala Phe Asn Thr Thr Gly Val Ser Ser Val Gln Thr Pro
                  95                 100                 105

 His Leu Pro Thr His Ala Asp Ser Gln Thr Pro Ser Ala Gly Thr
                 110                 115                 120

 Asp Thr Gln Thr Phe Ser Gly Ser Ala Ala Asn Ala Lys Leu Asn
                 125                 130                 135

 Pro Thr Pro Gly Ser Asn Ala Ile Ser Asp Val Pro Gly Glu Arg
                 140                 145                 150

 Ser Thr Ala Ser Thr Phe Pro Thr Asp Pro Val Ser Pro Leu Thr
                 155                 160                 165

 Thr Thr Leu Ser Leu Ala His His Ser Ser Ala Ala Leu Pro Ala
                 170                 175                 180

 Arg Thr Ser Asn Thr Thr Ile Thr Ala Asn Thr Ser Asp Ala Tyr
                 185                 190                 195

 Leu Asn Ala Ser Glu Thr Thr Thr Leu Ser Pro Ser Gly Ser Ala
                 200                 205                 210

 Val Ile Ser Thr Thr Thr Ile Ala Thr Thr Pro Ser Lys Pro Thr
                 215                 220                 225

 Cys Asp Glu Lys Tyr Ala Asn Ile Thr Val Asp Tyr Leu Tyr Asn
                 230                 235                 240

 Lys Glu Thr Lys Leu Phe Thr Ala Lys Leu Asn Val Asn Glu Asn
                 245                 250                 255

 Val Glu Cys Gly Asn Asn Thr Cys Thr Asn Asn Glu Val His Asn
                 260                 265                 270

 Leu Thr Glu Cys Lys Asn Ala Ser Val Ser Ile Ser His Asn Ser
                 275                 280                 285

 Cys Thr Ala Pro Asp Lys Thr Leu Ile Leu Asp Val Pro Pro Gly
                 290                 295                 300

 Val Glu Lys Phe Gln Leu His Asp Cys Thr Gln Val Glu Lys Ala
                 305                 310                 315

 Asp Thr Thr Ile Cys Leu Lys Trp Lys Asn Ile Glu Thr Phe Thr
                 320                 325                 330

 Cys Asp Thr Gln Asn Ile Thr Tyr Arg Phe Gln Cys Gly Asn Met
                 335                 340                 345

 Ile Phe Asp Asn Lys Glu Ile Lys Leu Glu Asn Leu Glu Pro Glu
                 350                 355                 360

 His Glu Tyr Lys Cys Asp Ser Glu Ile Leu Tyr Asn Asn His Lys
                 365                 370                 375

 Phe Thr Asn Ala Ser Lys Ile Ile Lys Thr Asp Phe Gly Ser Pro
                 380                 385                 390

 Gly Glu Pro Gln Ile Ile Phe Cys Arg Ser Glu Ala Ala His Gln
                 395                 400                 405

 Gly Val Ile Thr Trp Asn Pro Pro Gln Arg Ser Phe His Asn Phe
                 410                 415                 420

 Thr Leu Cys Tyr Ile Lys Glu Thr Glu Lys Asp Cys Leu Asn Leu
                 425                 430                 435

 Asp Lys Asn Leu Ile Lys Tyr Asp Leu Gln Asn Leu Lys Pro Tyr
                 440                 445                 450

 Thr Lys Tyr Val Leu Ser Leu His Ala Tyr Ile Ile Ala Lys Val
                 455                 460                 465

 Gln Arg Asn Gly Ser Ala Ala Met Cys His Phe Thr Thr Lys Ser
                 470                 475                 480

 Ala Pro Pro Ser Gln Val Trp Asn Met Thr Val Ser Met Thr Ser
                 485                 490                 495

 Asp Asn Ser Met His Val Lys Cys Arg Pro Pro Arg Asp Arg Asn
                 500                 505                 510

 Gly Pro His Glu Arg Tyr His Leu Glu Val Glu Ala Gly Asn Thr
                 515                 520                 525

 Leu Val Arg Asn Glu Ser His Lys Asn Cys Asp Phe Arg Val Lys
                 530                 535                 540

 Asp Leu Gln Tyr Ser Thr Asp Tyr Thr Phe Lys Ala Tyr Phe His
                 545                 550                 555

 Asn Gly Asp Tyr Pro Gly Glu Pro Phe Ile Leu His His Ser Thr
                 560                 565                 570

 Ser Tyr Asn Ser Lys Ala Leu Ile Ala Phe Leu Ala Phe Leu Ile
                 575                 580                 585

 Ile Val Thr Ser Ile Ala Leu Leu Val Val Leu Tyr Lys Ile Tyr
                 590                 595                 600

 Asp Leu His Lys Lys Arg Ser Cys Asn Leu Asp Glu Gln Gln Glu
                 605                 610                 615

 Leu Val Glu Arg Asp Asp Glu Lys Gln Leu Met Asn Val Glu Pro
                 620                 625                 630

 Ile His Ala Asp Ile Leu Leu Glu Thr Tyr Lys Arg Lys Ile Ala
                 635                 640                 645

 Asp Glu Gly Arg Leu Phe Leu Ala Glu Phe Gln Ser Ile Pro Arg
                 650                 655                 660

 Val Phe Ser Lys Phe Pro Ile Lys Glu Ala Arg Lys Pro Phe Asn
                 665                 670                 675

 Gln Asn Lys Asn Arg Tyr Val Asp Ile Leu Pro Tyr Asp Tyr Asn
                 680                 685                 690

 Arg Val Glu Leu Ser Glu Ile Asn Gly Asp Ala Gly Ser Asn Tyr
                 695                 700                 705

 Ile Asn Ala Ser Tyr Ile Asp Gly Phe Lys Glu Pro Arg Lys Tyr
                 710                 715                 720

 Ile Ala Ala Gln Gly Pro Arg Asp Glu Thr Val Asp Asp Phe Trp
                 725                 730                 735

 Arg Met Ile Trp Glu Gln Lys Ala Thr Val Ile Val Met Val Thr
                 740                 745                 750

 Arg Cys Glu Glu Gly Asn Arg Asn Lys Cys Ala Glu Tyr Trp Pro
                 755                 760                 765

 Ser Met Glu Glu Gly Thr Arg Ala Phe Gly Asp Val Val Val Lys
                 770                 775                 780

 Ile Asn Gln His Lys Arg Cys Pro Asp Tyr Ile Ile Gln Lys Leu
                 785                 790                 795

 Asn Ile Val Asn Lys Lys Glu Lys Ala Thr Gly Arg Glu Val Thr
                 800                 805                 810

 His Ile Gln Phe Thr Ser Trp Pro Asp His Gly Val Pro Glu Asp
                 815                 820                 825

 Pro His Leu Leu Leu Lys Leu Arg Arg Arg Val Asn Ala Phe Ser
                 830                 835                 840

 Asn Phe Phe Ser Gly Pro Ile Val Val His Cys Ser Ala Gly Val
                 845                 850                 855

 Gly Arg Thr Gly Thr Tyr Ile Gly Ile Asp Ala Met Leu Glu Gly
                 860                 865                 870

 Leu Glu Ala Glu Asn Lys Val Asp Val Tyr Gly Tyr Val Val Lys
                 875                 880                 885

 Leu Arg Arg Gln Arg Cys Leu Met Val Gln Val Glu Ala Gln Tyr
                 890                 895                 900

 Ile Leu Ile His Gln Ala Leu Val Glu Tyr Asn Gln Phe Gly Glu
                 905                 910                 915

 Thr Glu Val Asn Leu Ser Glu Leu His Pro Tyr Leu His Asn Met
                 920                 925                 930

 Lys Lys Arg Asp Pro Pro Ser Glu Pro Ser Pro Leu Glu Ala Glu
                 935                 940                 945

 Phe Gln Arg Leu Pro Ser Tyr Arg Ser Trp Arg Thr Gln His Ile
                 950                 955                 960

 Gly Asn Gln Glu Glu Asn Lys Ser Lys Asn Arg Asn Ser Asn Val
                 965                 970                 975

 Ile Pro Tyr Asp Tyr Asn Arg Val Pro Leu Lys His Glu Leu Glu
                 980                 985                 990

 Met Ser Lys Glu Ser Glu His Asp Ser Asp Glu Ser Ser Asp Asp
                 995                1000                1005

 Asp Ser Asp Ser Glu Glu Pro Ser Lys Tyr Ile Asn Ala Ser Phe
                1010                1015                1020

 Ile Met Ser Tyr Trp Lys Pro Glu Val Met Ile Ala Ala Gln Gly
                1025                1030                1035

 Pro Leu Lys Glu Thr Ile Gly Asp Phe Trp Gln Met Ile Phe Gln
                1040                1045                1050

 Arg Lys Val Lys Val Ile Val Met Leu Thr Glu Leu Lys His Gly
                1055                1060                1065

 Asp Gln Glu Ile Cys Ala Gln Tyr Trp Gly Glu Gly Lys Gln Thr
                1070                1075                1080

 Tyr Gly Asp Ile Glu Val Asp Leu Lys Asp Thr Asp Lys Ser Ser
                1085                1090                1095

 Thr Tyr Thr Leu Arg Val Phe Glu Leu Arg His Ser Lys Arg Lys
                1100                1105                1110

 Asp Ser Arg Thr Val Tyr Gln Tyr Gln Tyr Thr Asn Trp Ser Val
                1115                1120                1125

 Glu Gln Leu Pro Ala Glu Pro Lys Glu Leu Ile Ser Met Ile Gln
                1130                1135                1140

 Val Val Lys Gln Lys Leu Pro Gln Lys Asn Ser Ser Glu Gly Asn
                1145                1150                1155

 Lys His His Lys Ser Thr Pro Leu Leu Ile His Cys Arg Asp Gly
                1160                1165                1170

 Ser Gln Gln Thr Gly Ile Phe Cys Ala Leu Leu Asn Leu Leu Glu
                1175                1180                1185

 Ser Ala Glu Thr Glu Glu Val Val Asp Ile Phe Gln Val Val Lys
                1190                1195                1200

 Ala Leu Arg Lys Ala Arg Pro Gly Met Val Ser Thr Phe Glu Gln
                1205                1210                1215

 Tyr Gln Phe Leu Tyr Asp Val Ile Ala Ser Thr Tyr Pro Ala Gln
                1220                1225                1230

 Asn Gly Gln Val Lys Lys Asn Asn His Gln Glu Asp Lys Ile Glu
                1235                1240                1245

 Phe Asp Asn Glu Val Asp Lys Val Lys Gln Asp Ala Asn Cys Val
                1250                1255                1260

 Asn Pro Leu Gly Ala Pro Glu Lys Leu Pro Glu Ala Lys Glu Gln
                1265                1270                1275

 Ala Glu Gly Ser Glu Pro Thr Ser Gly Thr Glu Gly Pro Glu His
                1280                1285                1290

 Ser Val Asn Gly Pro Ala Ser Pro Ala Leu Asn Gln Gly Ser
                1295                1300

<210> 2625
<211> 2340
<212> DNA
<213> Homo sapien

<400> 2625
 aggcgctgcg gagacgcgta gaggagcgcg ccccccggcc gmtgccgmcc 50

 ctggcccgtg ccgtcacccc gcttctccgc gcctcgggcg gtacccagcc 100

 agtccccagc gccgcgctac cgcgctgacc ggccctccag acgcctcccg 150

 gtacccggga ccccagcccg gccgctcgcc cgcagcccgc cggccgcaca 200

 cgtccccgga gccgggccta gggcgggcgg cagggcggct cggcgcagtc 250

 aggctgggct ctgtagcgtc cccatggccg cggccggctg gcgggacggc 300

 tccggccagg agaagtaccg gctcgtggtg gtcggcgggg gcggcgtggg 350

 caagtcggcg ctcaccatcc agttcatcca gtcctatttt gtaacggatt 400

 atgatccaac cattgaagat tcttacacaa agcagtgtgt gatagatgac 450

 agagcagccc ggctagatat tttggataca gcaggacaag aagagtttgg 500

 agccatgaga gaacagtata tgaggactgg cgaaggcttc ctgttggtct 550

 tttcagtcac agatagaggc agttttgaag aaatctataa gtttcaaaga 600

 cagattctca gagtaaagga tcgtgatgag ttcccaatga ttttaattgg 650

 taataaagca gatctggatc atcaaagaca ggtaacacag gaagaaggac 700

 aacagttagc acggcagctt aaggtaacat acatggaggc atcagcaaag 750

 attaggatga atgtagatca agctttccat gaacttgtcc gggttatcag 800

 gaaatttcaa gagcaggaat gtcctccttc accagaacca acacggaaag 850

 aaaaagacaa gaaaggctgc cattgtgtca ttttctagaa tcccttcagt 900

 tttagctacc aacggccagg aaaagccctc atcttctctt tctctcctca 950

 gtttacatct tgttggtacc tttctagcct tagacaaatg atcaccatgt 1000

 tagccttaga cgaagaagct ggctagtcct ttctgtgaag ctaatacaat 1050

 ggtcatttcc agacaaattt aaaggaaaca ctaaggctgc ttcaaagatt 1100

 atctgattcc tttaaaatat atgtctatat acacagacat gctctttttt 1150

 taagtgctta cattttaata gagatgaatc agttttggaa tctaagctgt 1200

 ttgccaagct gaagctacag gttgtgaaat aatttttaac ttttggaatc 1250

 atactgccta ctgttactct aaatagaaat atagggtttt ttttaatgtg 1300

 aatttttgcc tatctttaaa catttcaatg tcagcctttg ttaaccttaa 1350

 atacactgaa ttgaatctac aaaagtgaac catctcagac ctttactgat 1400

 actacaactt ttgttttctg atggccaaaa taccaaatgc ctgttgtatt 1450

 tatggattaa aaactgctta taaaaccctg tgttactact cctactcttg 1500

 gagatgataa tattctatgt ggtcaaatat ttggactcat ttaggactta 1550

 gatatttcag tgtacttgat tttttaattt aactcttttt cacagccacg 1600

 ctaagggtaa aaaggaataa tttccttctg tcttcctttt caagtatttc 1650

 tgggtaaggg attcaaaaaa ctaaaactgt ttttgtttgt aatataaaat 1700

 atggaattga tctttccagg gtcagagatg attaatgttt ttgctatata 1750

 cttttataca ttattttctt atcaaactag ttaacaagta tttttatatg 1800

 tttgtaagca gatatgcttt catagcatac cttgtgtata tgtaaagata 1850

 agtatttaat tctcactgtt cacttttaac tgacaaagaa aaacaagtgg 1900

 aaactacaga aactgtggta gaacttttac ttgctggtct ggtcttggtt 1950

 gtacccatct ttggccagtc acataactac tcaagaaacc ttcccaatag 2000

 agtacaacag gatgagactc tgaaatcact ttcagtattc cctgctagat 2050

 attgattgtt atttcaagta ttaagtgtaa gcttttaatg gataattagt 2100

 ataactgtgg atggcatctg attttgtttt taattctgtg gattgtgttt 2150

 aagcaattca atagtatgtt cctgattttg agatgctaag tggtattgca 2200

 cagttgtcac tttatcaagt gtgtacaaca gtcccatgaa gtttatagag 2250

 catacccttg tatagcttca ggtgctagaa ttaaaattga tctgttatca 2300

 caaaaaaaaa aaaaaaaaaa aaaggctctt taattaggcg 2340

<210> 2626
<211> 1410
<212> DNA
<213> Homo sapien

<400> 2626
 cgcgcctcgg gcggtaccca gccagtcccc agcgccgcgc taccgcgctg 50

 accggccctc cagacgcctc ccggtacccg ggaccccagc ccggccgctc 100

 gcccgcagcc cgccggccgc acacgtcccc ggagccgggc ctagggcggg 150

 cggcagcggc ggctcggcgc agtcaggctg ggctctgtag cgtccccatg 200

 gccgcggccg gctggcggga cggctccggc caggagaagt accggctcgt 250

 ggtggtcggc gggggcggcg tgggcaagtc ggcgctcacc atccagttca 300

 tccagtccta ttttgtaacg gattatgatc caaccattga agattcttac 350

 acaaagcagt gtgtgataga tgacagagca gcccggctag atattttgga 400

 tacagcagga caagaagagt ttggagccat gagagaacag tatatgagga 450

 ctggcgaagg cttcctgttg gtcttttcag tcacagatag aggcagtttt 500

 gaagaaatct ataagtttca aagacagatt ctcagagtaa aggatcgtga 550

 tgagttccca atgattttaa ttggtaataa agcagatctg gatcatcaaa 600

 gacaggtaac acaggaagaa ggacaacagt tagcacggca gcttaaggta 650

 acatacatgg aggcatcagc aaagattagg atgaatgtag atcaagcttt 700

 ccatgaactt gtccgggtta tcaggaaatt tcaagagcag gaatgtcctc 750

 cttcaccaga accaacacgg aaagaaaaag acaagaaagg ctgccattgt 800

 gtcattttct agaatccctt cagttttagc taccaacggc caggaaaagc 850

 cctcatcttc tctttctctc ctcagtttac atcttgttgg tacctttcta 900

 gccttagaca aatgatcacc atgttagcct tagaccaaga agctggctag 950

 tcctttctgt gaagctaata caatggtcat ttccagacaa atttaaagga 1000

 aacactaagg ctgcttcaaa gattatctga ttcctttaaa atatatgtct 1050

 atatacacag acatgctctt tttttaagtg cttacatttt aatagagatg 1100

 aatcagtttt ggaatctaag ctgtttgcca agctgaagct acaggttgtg 1150

 aaataatttt taacttttgg aatcatactg cctactgtta ctctaaatag 1200

 aaatataggg ttttttttaa tgtgaatttt tgcctatctt taaacatttc 1250

 aatgtcagcc tttgttaacc ttaaatacac tgaattgaat ctacaaaagt 1300

 gaaccatctc agacctttac tgatactaca acttttgttt tctgatggcc 1350

 aaaataccaa atgcctgttg tatttatgga ttaaaaactg cttataaaaa 1400

 aaaaaaaaaa 1410

<210> 2627
<211> 204
<212> PRT
<213> Homo sapien

<400> 2627
 Met Ala Ala Ala Gly Trp Arg Asp Gly Ser Gly Gln Glu Lys Tyr
   1               5                  10                  15

 Arg Leu Val Val Val Gly Gly Gly Gly Val Gly Lys Ser Ala Leu
                  20                  25                  30

 Thr Ile Gln Phe Ile Gln Ser Tyr Phe Val Thr Asp Tyr Asp Pro
                  35                  40                  45

 Thr Ile Glu Asp Ser Tyr Thr Lys Gln Cys Val Ile Asp Asp Arg
                  50                  55                  60

 Ala Ala Arg Leu Asp Ile Leu Asp Thr Ala Gly Gln Glu Glu Phe
                  65                  70                  75

 Gly Ala Met Arg Glu Gln Tyr Met Arg Thr Gly Glu Gly Phe Leu
                  80                  85                  90

 Leu Val Phe Ser Val Thr Asp Arg Gly Ser Phe Glu Glu Ile Tyr
                  95                 100                 105

 Lys Phe Gln Arg Gln Ile Leu Arg Val Lys Asp Arg Asp Glu Phe
                 110                 115                 120

 Pro Met Ile Leu Ile Gly Asn Lys Ala Asp Leu Asp His Gln Arg
                 125                 130                 135

 Gln Val Thr Gln Glu Glu Gly Gln Gln Leu Ala Arg Gln Leu Lys
                 140                 145                 150

 Val Thr Tyr Met Glu Ala Ser Ala Lys Ile Arg Met Asn Val Asp
                 155                 160                 165

 Gln Ala Phe His Glu Leu Val Arg Val Ile Arg Lys Phe Gln Glu
                 170                 175                 180

 Gln Glu Cys Pro Pro Ser Pro Glu Pro Thr Arg Lys Glu Lys Asp
                 185                 190                 195

 Lys Lys Gly Cys His Cys Val Ile Phe
                 200

<210> 2628
<211> 2319
<212> DNA
<213> Homo sapien

<400> 2628
 cgaccacccg gcctcggcca ataagcgccg ccctctcgcc cccgtgttac 50

 tgggtagaag aaaacaaaaa caaacagagc gagaagggcc agagactctc 100

 cgaggcggcg gcagagacag aagagcgggg tcggggccgg ctgaccagga 150

 acctgggcga gcagcggcgg gggcccgagg gattctgaag gaagatttcc 200

 attaggtaat ttgtttaatc agtgcaagcg aaattaaggg aaaatggatg 250

 tagaaaatga gcagatactg aatgtaaacc ctgcagatcc tgataactta 300

 agtgactctc tcttttccgg tgatgaagaa aatgctggga ctgaggaaat 350

 aaagaatgaa ataaatggaa attggatttc agcatcctcc attaacgaag 400

 ctagaattaa tgccaaggca aaaaggcgac taaggaaaaa ctcatcccgg 450

 gactctggca gaggcgattc ggtcagcgac agtgggagtg acgcccttag 500

 aagtggatta actgtgccaa ccagtccaaa gggaaggttg ctggataggc 550

 gatccagatc tgggaaagga aggggactac caaagaaagg tggtgcagga 600

 ggcaaaggtg tctggggtac acctggacag gtgtatgatg tggaggaggt 650

 ggatgtgaaa gatcctaact atgatgatga ccaggagaac tgtgtttatg 700

 aaactgtagt tttgcctttg gatgaaaggg catttgagaa gactttaaca 750

 ccaatcatac aggaatattt tgagcatgga gatactaatg aagttgcgga 800

 aatgttaaga gatttaaatc ttggtgaaat gaaaagtgga gtaccagtgt 850

 tggcagtatc cttagcattg gaggggaagg ctagtcatag agagatgaca 900

 tctaagcttc tttctgacct ttgtgggaca gtaatgagca caactgatgt 950

 ggaaaaatca tttgataaat tgttgaaaga tctacctgaa ttagcactgg 1000

 atactcctag agcaccacag ttggtgggcc agtttattgc tagagctgtt 1050

 ggagatggaa ttttatgtaa tacctatatt gatagttaca aaggaactgt 1100

 agattgtgtg caggctagag ctgctctgga taaggctacc gtgcttctga 1150

 gtatgtctaa aggtggaaag cgtaaagata gtgtgtgggg ctctggaggt 1200

 gggcagcaat ctgtcaatca ccttgttaaa gagattgata tgctgctgaa 1250

 agaatattta ctctctggag acatatctga agctgaacat tgccttaagg 1300

 aactggaagt acctcatttt caccatgagc ttgtatatga agctattata 1350

 atggttttag agtcaactgg agaaagtaca tttaagatga ttttggattt 1400

 attaaagtcc ctttggaagt cttctaccat tactgtagac caaatgaaaa 1450

 gaggttatga gagaatttac aatgaaattc cggacattaa tctggatgtc 1500

 ccacattcat actctgtgct ggagcggttt gtagaagaat gttttcaggc 1550

 tggaataatt tccaaacaac tcagagatct ttgtccttca aggggcagaa 1600

 agcgttttgt aagcgaagga gatggaggtc gtcttaaacc agagagctac 1650

 tgaatataag aactcttgca gtcttagatg ttataaaaat atatatctga 1700

 attgtaagag ttgttagcac aagttttttt tttttttttt tttaagcact 1750

 tgttttgggt acaaggcatt tctgacattt tataaaccta catttaaggg 1800

 gaatttttaa aggaaatgtt ttttcttttt tttttgtttt tcgagggggc 1850

 aaggagggac agaaaagtaa cctcttctta agtggaatat tctaataagc 1900

 taccttttgt aagtgccatg tttattatct aatcattcca agttttgcat 1950

 tgatgtctga ctgccactcc tttctttcaa ggacagtgtt ttttgtagta 2000

 aaatcactgg tttatacaaa gctttattta gggggtaaag ttaagctgct 2050

 aaaaccccat gttggctgct gctgttgaga tactgtgctt tgggagtaaa 2100

 aaaagaaagt tatttctttg tcttaaagaa tttttaaaaa attagtcatg 2150

 agacttattc atctttccag ggaacatact gattggtctt aaaagactag 2200

 acagttaagt aaaaggtggc tggaacatct atttttctac aaaactggaa 2250

 aaatgaacct ggttctagaa gaatgtacac caaaataaaa catgtgaagc 2300

 agtaaaaaaa aaaaaaaaa 2319

<210> 2629
<211> 469
<212> PRT
<213> Homo sapien

<400> 2629
 Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp
   1               5                  10                  15

 Pro Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn
                  20                  25                  30

 Ala Gly Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile
                  35                  40                  45

 Ser Ala Ser Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys
                  50                  55                  60

 Arg Arg Leu Arg Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp
                  65                  70                  75

 Ser Val Ser Asp Ser Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr
                  80                  85                  90

 Val Pro Thr Ser Pro Lys Gly Arg Leu Leu Asp Arg Arg Ser Arg
                  95                 100                 105

 Ser Gly Lys Gly Arg Gly Leu Pro Lys Lys Gly Gly Ala Gly Gly
                 110                 115                 120

 Lys Gly Val Trp Gly Thr Pro Gly Gln Val Tyr Asp Val Glu Glu
                 125                 130                 135

 Val Asp Val Lys Asp Pro Asn Tyr Asp Asp Asp Gln Glu Asn Cys
                 140                 145                 150

 Val Tyr Glu Thr Val Val Leu Pro Leu Asp Glu Arg Ala Phe Glu
                 155                 160                 165

 Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe Glu His Gly Asp
                 170                 175                 180

 Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn Leu Gly Glu
                 185                 190                 195

 Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala Leu Glu
                 200                 205                 210

 Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser Asp
                 215                 220                 225

 Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe
                 230                 235                 240

 Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro
                 245                 250                 255

 Arg Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly
                 260                 265                 270

 Asp Gly Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr
                 275                 280                 285

 Val Asp Cys Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val
                 290                 295                 300

 Leu Leu Ser Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp
                 305                 310                 315

 Gly Ser Gly Gly Gly Gln Gln Ser Val Asn His Leu Val Lys Glu
                 320                 325                 330

 Ile Asp Met Leu Leu Lys Glu Tyr Leu Leu Ser Gly Asp Ile Ser
                 335                 340                 345

 Glu Ala Glu His Cys Leu Lys Glu Leu Glu Val Pro His Phe His
                 350                 355                 360

 His Glu Leu Val Tyr Glu Ala Ile Ile Met Val Leu Glu Ser Thr
                 365                 370                 375

 Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu Lys Ser Leu
                 380                 385                 390

 Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg Gly Tyr
                 395                 400                 405

 Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val Pro
                 410                 415                 420

 His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln
                 425                 430                 435

 Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg
                 440                 445                 450

 Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys
                 455                 460                 465

 Pro Glu Ser Tyr


<210> 2630
<211> 1897
<212> DNA
<213> Homo sapien

<400> 2630
 ctccgaacag gaagaggacg aaaaaaataa ccgtccgcga cgccgagaca 50

 aaccggaccc gcaaccacca tgaacagcaa aggtcaatat ccaacacagc 100

 caacctaccc tgtgcagcct cctgggaatc cagtataccc tcagaccttg 150

 catcttcctc aggctccacc ctataccgat gctccacctg cctactcaga 200

 gctctatcgt ccgagctttg tgcacccagg ggctgccaca gtccccacca 250

 tgtcagccgc atttcctgga gcctctctgt atcttcccat ggcccagtct 300

 gtggctgttg ggcctttagg ttccacaatc cccatggctt attatccagt 350

 cggtcccatc tatccacctg gctccacagt gctggtggaa ggagggtatg 400

 atgcaggtgc cagatttgga gctggggcta ctgctggcaa cattcctcct 450

 ccacctcctg gatgccctcc caatgctgct cagcttgcag tcatgcaggg 500

 agccaacgtc ctcgtaactc agcggaaggg gaacttcttc atgggtggtt 550

 cagatggtgg ctacaccatc tggtgaggaa ccaaggccac ctctgtgccg 600

 ggaaagacat cacatacctt cagcacttct cacaatgtaa ctgctttagt 650

 catattaacc tgaagttgca gtttagacac atgttgttgg ggtgtctttc 700

 tggtgcccaa actttcaggc acttttcaaa tttaataagg aaccatgtaa 750

 tggtagcagt acctccctaa agcattttga ggtaggggag gtatccattc 800

 ataaaatgaa tgtgggtgaa gccgccctaa ggattttcct ttaatttctc 850

 tggagtaata ctgtaccata ctggtctttg cttttagtaa taaaacatca 900

 aattaggttt ggagggaact ttgatcttcc taagaattaa agttgccaaa 950

 ttattctgat tggtctttaa tctcctttaa gtctttgata tatattactt 1000

 gttataaatg gaacgcatta gttgtctgcc ttttcctttc catcccttgc 1050

 cccacccatc ccatctccaa ccctagtctt ccatttcctc ccgccagtct 1100

 ccattgaatc aatggtgcag gacagaaagc cagtcagact aatttccttc 1150

 tttcctcgca cttctcccca ctcgtcatct tttaactagt gtttcacaag 1200

 gatcctctga aaccctctct gtgccccaag tacagatgcc attacttctg 1250

 ctttcgtatc tcctcaggca aaagtggagg gtgccttatg ggccctcctc 1300

 ataggttgtc tctgcataca cgaacctaac ccaaatttgc tttggtgcca 1350

 gaaaaactga gctatgtttg aacaaagatg tcgtgcaaac tgtactgtga 1400

 acaacagttg gtttaaaata tgaggggcaa ggaggaggat gcatttcaaa 1450

 agcttgattg atgtgttcag agctaaatta agaggagttt tcagatcaaa 1500

 aactggttac cattttttgt cagagtgtct gatgcggcca ctcattcggc 1550

 tccccagaat tcctagactg ggttaatagg gtcatattgt gaatgtctca 1600

 ctacaaaatg acttgagtcc agtgaaatct cattagggtt taagaatatt 1650

 tcagggatcc ttaatgtttt gatttttgtt ttctgaaatt ggattttatt 1700

 ttattttatc ttataatttc agttcatcta aattgtgtgt tctgtacatg 1750

 tgatgtttga ctgtaccatt gactgttatg gaagttcagc gttgtatgtc 1800

 tctctctaca ctgtggtgca cttaacttgt ggaattttta tactaaaaat 1850

 gtagaataaa gactattttg aagatttgaa taaagtgatg aagttgc 1897

<210> 2631
<211> 168
<212> PRT
<213> Homo sapien

<400> 2631
 Met Asn Ser Lys Gly Gln Tyr Pro Thr Gln Pro Thr Tyr Pro Val
   1               5                  10                  15

 Gln Pro Pro Gly Asn Pro Val Tyr Pro Gln Thr Leu His Leu Pro
                  20                  25                  30

 Gln Ala Pro Pro Tyr Thr Asp Ala Pro Pro Ala Tyr Ser Glu Leu
                  35                  40                  45

 Tyr Arg Pro Ser Phe Val His Pro Gly Ala Ala Thr Val Pro Thr
                  50                  55                  60

 Met Ser Ala Ala Phe Pro Gly Ala Ser Leu Tyr Leu Pro Met Ala
                  65                  70                  75

 Gln Ser Val Ala Val Gly Pro Leu Gly Ser Thr Ile Pro Met Ala
                  80                  85                  90

 Tyr Tyr Pro Val Gly Pro Ile Tyr Pro Pro Gly Ser Thr Val Leu
                  95                 100                 105

 Val Glu Gly Gly Tyr Asp Ala Gly Ala Arg Phe Gly Ala Gly Ala
                 110                 115                 120

 Thr Ala Gly Asn Ile Pro Pro Pro Pro Pro Gly Cys Pro Pro Asn
                 125                 130                 135

 Ala Ala Gln Leu Ala Val Met Gln Gly Ala Asn Val Leu Val Thr
                 140                 145                 150

 Gln Arg Lys Gly Asn Phe Phe Met Gly Gly Ser Asp Gly Gly Tyr
                 155                 160                 165

 Thr Ile Trp


<210> 2632
<211> 2849
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 410-603
<223> Unknown base

<400> 2632
 tggactatga gactggacat atctcgttct acaatgccac ggatggatct 50

 catatctaca catttctgca cgcctcttcc tctgagcctc tgtatcctgt 100

 attcagaatt ttgaccttgg agcccactgc cctgaccgtt tgcccaatac 150

 caaaagtaga gagttccccc gatcccgacc tagtgcctga tcattccctg 200

 gagataccag tgaccccagg cttagctaat gaaagtgggg agcctcaggc 250

 tgaagtaaca tctctgcttc tccctgccca gcctggagct aagggtctca 300

 ccctccacaa cagccagtca gaaccataaa gctacaggca cacactgaag 350

 cactttactg atattcattc gattattcca taggacagtt gtttgagatt 400

 ggtgccaccn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nnntgtcagg tagtctcatt tggcaagtat ggaagcagag gcagggcaac 650

 attaagtagc ttacataact cacacggtaa tttgtgcagt tgggagatgt 700

 tcagcttcag tcctggccaa ttgcccgttc ttttccagcc tgatttttcc 750

 cgcatgggaa gaacccacat gtagccctga ggttcccttc ccaggacagc 800

 tccaggatcg agatcactgt gagtggttgt ggagttaaga cccctatgga 850

 ctccttccca gctgattatc agagccttag acccagcact ccttggattg 900

 gctctgcaga gtgtcttggt tgagagaatc acattcaggg caggctaggg 950

 acacggggtt ctggaaggac ctcctcagca tggcccaagc cttgcatgct 1000

 gtggctctta aatccaggaa aaatggctga ccccatggac acctcctcaa 1050

 actctctgca gcagatgtaa ttctgtatcc agacatggca aatgccatcc 1100

 tccttgtttc tgaggaccag aggagtgtac agcgtgctga ggagccccat 1150

 gacctaccag acaaccctga gagatttgaa tggcgttact gtgtgcttgg 1200

 ctgtgaaagc ttcatgtcag agagacacta ctgggaggtg gaagtggggg 1250

 acagaaaaga gtggcatatt ggggtatgta gtaagaacgt ggagaggaaa 1300

 aaagtttggg tcaaaatgac accggagaac ggatactgga ctatgggcct 1350

 gactgatggg aataagtatc gggctctcac tgagcccaga accaacctga 1400

 aacttcctga gcctcctagg aaagtggggg tcatcctgga ctatgagact 1450

 ggacatatct cgttctacaa tgccacggat ggatctcata tctacacatt 1500

 tctgcacgcc tcttcctctg agcctctgta tcctgtattc agaattttga 1550

 ccttggagcc cactgccctg accgtttgcc caataccaaa agtagagagt 1600

 tcccccgatc ccgacctagt gcctgatcat tccctggaga taccactgac 1650

 cccaggctta gctaatgaaa gtggggagcc tcaggctgaa gtaacatctc 1700

 tgcttctccc tgcccagcct ggagctaagg gtctcaccct ccacaacagc 1750

 cagtcagaac cataaagcta caggcacaca ctgaagcact ttactgatat 1800

 tcattcaatt attccatagg acagttgttt gagtttggtg ccaccttatt 1850

 ggccccttta tacagataag gaaactgggg tgtagaaaag tgtattgact 1900

 ttacaaagca gacaggaata gtgaacaaca gagctgggat ctgaacaaca 1950

 atgactaaca ttaatggaga atttaaaacg ttctgagtgc tgtgttatga 2000

 gctttggtgg gtgtcactcc tttaatcctc acaacaccct gtcaggtagt 2050

 ctcatttggc aagtatggaa gcagaggcag ggcaacatta agtagcttac 2100

 ataactcaca cggtaatttg tgcagttggg agatgttcag cttcagtccc 2150

 tggccaattg cccgttcttt tccagcctga tttttcctgc atgggaagag 2200

 cccacatgta gccctgaggt tcccttccca ggacagctcc aggatcgaga 2250

 tcactgtgag tggttgtgga gttaagaccc ctatggactc cttcccagct 2300

 gattatcaga gccttagacc cagcactcct tggattggct ctgcagagtg 2350

 tcttggttga gagaataacg ttgcagttcc cacagggcat gtgactttga 2400

 aagagactag aggccacact cagttaataa tggggcacag atgtgttccc 2450

 acccaacaaa tgtgataagt gatcgtgcag ccagagccag ccttccttca 2500

 gtcaaggttt ccaggcagag caaataccct agagattctc tgtaatattg 2550

 gtaatttgga tgaaggaagc tagaagaatt acagggatgt ttttaatccc 2600

 actatggact cagtctcctg gaaaaggatc tgtccactcc tggtcattgg 2650

 tggatgttaa acccatattc ctttcaactg ctgcctgcta gggaaaactg 2700

 ctcctcatta tcatcactat tattgctcac cactgtatcc cctctactgg 2750

 gcaagtgctt gtcaagttct agttgttcaa taaatttgtt aataatgctg 2800

 aaaaaaaatc tatgtcgggt gcggagaaag aggtaatgaa atggcagga 2849

<210> 2633
<211> 226
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 410-603
<223> Unknown amino acid

<400> 2633
 Met Ala Asn Ala Ile Leu Leu Val Ser Glu Asp Gln Arg Ser Val
   1               5                  10                  15

 Gln Arg Ala Glu Glu Pro His Asp Leu Pro Asp Asn Pro Glu Arg
                  20                  25                  30

 Phe Glu Trp Arg Tyr Cys Val Leu Gly Cys Glu Ser Phe Met Ser
                  35                  40                  45

 Glu Arg His Tyr Trp Glu Val Glu Val Gly Asp Arg Lys Glu Trp
                  50                  55                  60

 His Ile Gly Val Cys Ser Lys Asn Val Glu Arg Lys Lys Val Trp
                  65                  70                  75

 Val Lys Met Thr Pro Glu Asn Gly Tyr Trp Thr Met Gly Leu Thr
                  80                  85                  90

 Asp Gly Asn Lys Tyr Arg Ala Leu Thr Glu Pro Arg Thr Asn Leu
                  95                 100                 105

 Lys Leu Pro Glu Pro Pro Arg Lys Val Gly Val Ile Leu Asp Tyr
                 110                 115                 120

 Glu Thr Gly His Ile Ser Phe Tyr Asn Ala Thr Asp Gly Ser His
                 125                 130                 135

 Ile Tyr Thr Phe Leu His Ala Ser Ser Ser Glu Pro Leu Tyr Pro
                 140                 145                 150

 Val Phe Arg Ile Leu Thr Leu Glu Pro Thr Ala Leu Thr Val Cys
                 155                 160                 165

 Pro Ile Pro Lys Val Glu Ser Ser Pro Asp Pro Asp Leu Val Pro
                 170                 175                 180

 Asp His Ser Leu Glu Ile Pro Leu Thr Pro Gly Leu Ala Asn Glu
                 185                 190                 195

 Ser Gly Glu Pro Gln Ala Glu Val Thr Ser Leu Leu Leu Pro Ala
                 200                 205                 210

 Gln Pro Gly Ala Lys Gly Leu Thr Leu His Asn Ser Gln Ser Glu
                 215                 220                 225

 Pro


<210> 2634
<211> 5577
<212> DNA
<213> Homo sapien

<400> 2634
 ggcaaccatg gcgggaggaa tgaaagtggc ggtctcgccg gcagttggtc 50

 ccgggccctg gggctcggga gtcgggggcg gtgggacagt gcggctactc 100

 ttgatcctct ccggctgctt ggtctacggc acagctgaaa ctgatgtaaa 150

 tgtggtcatg cttcaggaat cccaagtttg tgaaaagcgt gccagccaac 200

 aattctgtta cacaaatgtg cttatcccaa aatggcatga tatatggaca 250

 cggatacaga tccgagtaaa tagttccaga ttggttcgag tcacccaggt 300

 ggagaatgag gagaaactga aggagctaga gcagtttagt atctggaact 350

 ttttttcctc ctttttaaaa gagaaattga atgacaccta tgttaacgtg 400

 ggtctataca gcacaaaaac ctgcctcaaa gttgagatta tagagaagga 450

 caccaagtac agtgtcattg tgatccggag atttgatccc aaactctttc 500

 ttgttttcct tcttggactt atgctatttt tttgtggaga cttgctgagc 550

 agaagtcaaa ttttctacta ctctactggg atgactgtgg gaattgtggc 600

 ctctctgcta atcatcattt ttatactatc taagtttatg cctaagaaaa 650

 gtcccattta cgtcatcctg gtgggaggct ggtctttttc tctgtacctc 700

 attcaactag tttttaaaaa tttacaagag atctggaggt gttactggca 750

 gtatctttta agttatgtcc tcacagttgg attcatgagt tttgcagtat 800

 gttacaagta tgggcccttg gagaatgaac gaagtatcaa cctgctgacc 850

 tggaccttgc agctgatggg cctgtgtttc atgtattctg gcatccagat 900

 accacatatt gcccttgcca ttatcatcat tgctctttgt actaagaacc 950

 tggaacaccc tattcagtgg ctgtacatca cctgcagaaa ggtgtgtaag 1000

 ggagcagaaa agcctgttcc ccctcgtctc ctgacagaag aagaatatcg 1050

 gatacaagga gaggtagaaa cccgaaaggc tttagaggag ctccgagaat 1100

 tttgtaacag tccagactgc tctgcttgga agactgtttc tcgaatccag 1150

 tctccaaaaa gatttgctga ctttgtggaa ggctcttccc acctcacgcc 1200

 aaatgaagtt tctgtccatg agcaggagta tggattaggg agcattattg 1250

 cccaggatga aatctatgag gaagcatcct ctgaggagga ggactcatat 1300

 tctcggtgtc ctgctatcac acagaacaac tttctaacct aggtagtggt 1350

 cagttatctt tacgtggact ggcttggtgc cttggtccat gttgcatgtg 1400

 ttgtgcaatt gctttcaacc ctttgaaaca gagtgagata gatagggtag 1450

 aaattctcct actgaaataa gaggcctaaa aaggcctccc tttggaaatg 1500

 ggaggtctct atgggatccc tgaggaagga gagtggataa agtagtgaat 1550

 gctgggtagt tcacttccca ttggttaagc taacagccca cttttatgtt 1600

 tccagagaaa ttggatggcc acagctagca tggcattcta gctccttctt 1650

 gaaagttgat tcaatcatgg catttctgtc actggctggc tctccaaagt 1700

 aagaactgtt gttaagtgca ggaatgcttt tagactatag gctgcaactt 1750

 ccagagagaa atccacaaat ctgagcctcc ttcactccag cttttatttc 1800

 agtgacttta gaataattat tgatttaact gttttgggag gaaaatagat 1850

 ttttattgtt ttgtttttta aatgaatgtc ttttaaaaaa cataacaaac 1900

 tcatgttcca gaaccagcaa gtgctccaga gtgacacacc ccctaggccc 1950

 ctacatattt attaatatgg attatccatt aaagccccag gagctgttgt 2000

 tttaagcttt gatttagttc tcatacatat gatagaaagt cctatttgcc 2050

 tttaggaaca tgcctgtagg ctcttctgca ggtgagatgt actgggcttt 2100

 ttattatatt caactttcaa ttccatctta aaaaacattt gtattcttct 2150

 cttcccattc ttccttaccc tgcctttgcc ctttcaggaa gggtcagttc 2200

 ccttacctgt gaactatgta tgttcagagt agcattattc ctgctagcta 2250

 ggagaagtca tcttgtttag gggatttgga tgctttttat acgttctcca 2300

 ttttcctgtc attgggtcat gttatctttg agttgctatg aaatcaggaa 2350

 actgtctcct tttcctttcc cttcctttgt ctacatgctc tgtccattcc 2400

 tttcagcctt ttctcaccac ccatactccc ccaaatctgg gtaattttta 2450

 agccttgaaa ctatgtagtt tcttgataca caatttgtag ttatgcagca 2500

 gccacaattt gcattgccag gaaataggct ccaggttatc ttcatgcctc 2550

 tgggtgctca ttcagctgtc aagtttccat gaacttacac ttatttatga 2600

 ttgcgtttct gacctgagat gtatgctgcc tgttattgca gtagcattag 2650

 tttcagattc ttttgccatt gcaaagtacc ccttataaac cagcaatgtc 2700

 atctgtgagg aagcaaattc tcaagtgtct gtcatttact tggttctttt 2750

 tctttgtggt cttcaccctt ataccctgga aaagtctgta attaccttag 2800

 ccaggaagat agatggtcat ggcaagcgca cagcaccaga cttactggct 2850

 caccaagatg atggaaaaag gcagatgatt ttttaaaaag ccgtaatgac 2900

 tcctttagac cagccattta gcgtggtaat tttgaaaggc ctagctccat 2950

 tgcagacttc caaagggtca gctctgagac tgccctccag gtgggcagtt 3000

 gattatttcc accagtgttt tccagagcct taaactgtcc taagtgacaa 3050

 ctacctcagt tggcaggaaa gagacatata gtagaaagtg aaaaatgagc 3100

 agtatttggg cagatgctat gggttacagt tgaagggtaa aaggaacttt 3150

 acattgggaa acctttatac ccttgtgaat tatgtacatg gtaaaatgtt 3200

 ctctctctac aaagaactat taaaacttct gaaatatact attttttacc 3250

 ttatttatag aaattgagac ctagcatatt taagcataag tttattttaa 3300

 aaaataattc aactcgtgca agtggtctca ggattctctg gagattttgg 3350

 tgcctcccct acttagggag gtgatagctt gcctataagg gtgacttttc 3400

 ctgatcatgt ctttatttca atgagaaagc actgtgaaat tgtgaaagat 3450

 tctcctcttt ctctgtttaa taaaccccca tgaaatatag tttccatctc 3500

 tagaccagtt ttttttccac cgtgtttaga cttgaggtga ataaaatcaa 3550

 actgtttttt actccctatc tggtagttgg agacctgagc tgtaggcagt 3600

 ggagatggca attggttctg cagcctgaga gttgctctca cacagtgaag 3650

 gacggtgctg ctctggtgtg ctgtgtgtcc ttgccctgcc tgcctgtggc 3700

 tctgcccaga tgcttcagat cctctgtgtt ccggagattg cttgacttca 3750

 accttcttta ggagctgctc ttgtctccct cttggccact tagtttgctg 3800

 gctcagtcac tacttgaaga ccccatttaa tttttctctg gcagttatag 3850

 ctcttgtgat ttcagtacag tctcatctct cagaccaatc tcatcaagaa 3900

 ggattgaagg gataactatg aggtaagctg gacattggag ccgtgtttgc 3950

 tgccacgtca gcgtcttgct gggtgaatgt caagccataa atgggctcca 4000

 gggctctgga tctcatcagc attggaaatc tattgcctct catcagtctg 4050

 accaaattat gtagagcatt aatgtagaga ctcccattaa tgggaataca 4100

 agaggcagct ggcataaaac atttctttca ctttcctttc ccactcagat 4150

 tgcttcaaga gaccaacaga acacagggat caaaaacaag gaaaatttag 4200

 caacttcatt accttctaat aagtaattcc tgttagccac tgcatcccac 4250

 caaaactagt ttatttttcc cctcaaattc atgattttta cgtctgttac 4300

 aaagggaatt ttgctgatag ctctttgggt cccactgttc cattttatgc 4350

 taatagattc cattctaggg cccagccgtc tcttgactga tggtgttccc 4400

 tttaaccctt ggcatgtata atagaatttt ggtgaatgaa agaacccaaa 4450

 taggccagat agtcccccca ggccctgata tccataaaag gcttgggaat 4500

 gcattatgta attgtcctta gtctttttgt tgttttagaa aaaaaaaaca 4550

 agatgggctc agatggatgc ctacgtaaaa atggttccta gctgtgtact 4600

 cataactttt ctttgaattg agtagtgaaa ggaaggagga ggaaaggaaa 4650

 ttaaatgtcc ttctagtatt ctctggactc aagtctgaca tatgagataa 4700

 taacctatat tgaaatgcca agaattgtat ctgaaacaag agaacagttt 4750

 gacacattta tcatgccttc atattacata ttaactgaaa ccaattaata 4800

 aacatatgaa atatccattg cacaaggcaa aggcacctaa accttttgtt 4850

 tctttttcta catagcagaa attgattttt tttttatttt tttaggggaa 4900

 cctatataat tatgacccag tgatgtcttt tggtgactta agcttatgaa 4950

 ttcaggttac aattgagttg attctagatg gttactacct tgaaaaggat 5000

 gttggtgcct tatgtgacac gagccagagc ctgctgggaa taaacaaagc 5050

 agattcatgc caacaccaac tcgtagcttt agtggcagat gggagtggtc 5100

 acagactccc aaaatgtggg gctttggatt tccacaccat cccacgtgtg 5150

 tgtcatcttc ctctttcaca ctcttgatga taatttgaaa atgatgaaat 5200

 cacctctgaa tttgcctata gcatgagcac attcttatga caacataaca 5250

 aatagttcat aatgtgaata ttagaaactg ttacagcctg cagttaccat 5300

 aattttccat gtttgtggaa ttgatattga aatagcaggg ctaaggaatt 5350

 actggcaagt tttagcctgt gggtaatacc ttagggttat ttaaatattt 5400

 gtaattttat ttaaatgttc atgaatgttt gaaaggaaca aaattatcag 5450

 ggatggctct ttgccatggg tcttattttc accctctttt ctgtaagaaa 5500

 aaagaacaat gtcttaatgt atttttaaag tttttggtat agtttctaat 5550

 tccaatttta ataaaagttt tatagat 5577

<210> 2635
<211> 446
<212> PRT
<213> Homo sapien

<400> 2635
 Ala Thr Met Ala Gly Gly Met Lys Val Ala Val Ser Pro Ala Val
   1               5                  10                  15

 Gly Pro Gly Pro Trp Gly Ser Gly Val Gly Gly Gly Gly Thr Val
                  20                  25                  30

 Arg Leu Leu Leu Ile Leu Ser Gly Cys Leu Val Tyr Gly Thr Ala
                  35                  40                  45

 Glu Thr Asp Val Asn Val Val Met Leu Gln Glu Ser Gln Val Cys
                  50                  55                  60

 Glu Lys Arg Ala Ser Gln Gln Phe Cys Tyr Thr Asn Val Leu Ile
                  65                  70                  75

 Pro Lys Trp His Asp Ile Trp Thr Arg Ile Gln Ile Arg Val Asn
                  80                  85                  90

 Ser Ser Arg Leu Val Arg Val Thr Gln Val Glu Asn Glu Glu Lys
                  95                 100                 105

 Leu Lys Glu Leu Glu Gln Phe Ser Ile Trp Asn Phe Phe Ser Ser
                 110                 115                 120

 Phe Leu Lys Glu Lys Leu Asn Asp Thr Tyr Val Asn Val Gly Leu
                 125                 130                 135

 Tyr Ser Thr Lys Thr Cys Leu Lys Val Glu Ile Ile Glu Lys Asp
                 140                 145                 150

 Thr Lys Tyr Ser Val Ile Val Ile Arg Arg Phe Asp Pro Lys Leu
                 155                 160                 165

 Phe Leu Val Phe Leu Leu Gly Leu Met Leu Phe Phe Cys Gly Asp
                 170                 175                 180

 Leu Leu Ser Arg Ser Gln Ile Phe Tyr Tyr Ser Thr Gly Met Thr
                 185                 190                 195

 Val Gly Ile Val Ala Ser Leu Leu Ile Ile Ile Phe Ile Leu Ser
                 200                 205                 210

 Lys Phe Met Pro Lys Lys Ser Pro Ile Tyr Val Ile Leu Val Gly
                 215                 220                 225

 Gly Trp Ser Phe Ser Leu Tyr Leu Ile Gln Leu Val Phe Lys Asn
                 230                 235                 240

 Leu Gln Glu Ile Trp Arg Cys Tyr Trp Gln Tyr Leu Leu Ser Tyr
                 245                 250                 255

 Val Leu Thr Val Gly Phe Met Ser Phe Ala Val Cys Tyr Lys Tyr
                 260                 265                 270

 Gly Pro Leu Glu Asn Glu Arg Ser Ile Asn Leu Leu Thr Trp Thr
                 275                 280                 285

 Leu Gln Leu Met Gly Leu Cys Phe Met Tyr Ser Gly Ile Gln Ile
                 290                 295                 300

 Pro His Ile Ala Leu Ala Ile Ile Ile Ile Ala Leu Cys Thr Lys
                 305                 310                 315

 Asn Leu Glu His Pro Ile Gln Trp Leu Tyr Ile Thr Cys Arg Lys
                 320                 325                 330

 Val Cys Lys Gly Ala Glu Lys Pro Val Pro Pro Arg Leu Leu Thr
                 335                 340                 345

 Glu Glu Glu Tyr Arg Ile Gln Gly Glu Val Glu Thr Arg Lys Ala
                 350                 355                 360

 Leu Glu Glu Leu Arg Glu Phe Cys Asn Ser Pro Asp Cys Ser Ala
                 365                 370                 375

 Trp Lys Thr Val Ser Arg Ile Gln Ser Pro Lys Arg Phe Ala Asp
                 380                 385                 390

 Phe Val Glu Gly Ser Ser His Leu Thr Pro Asn Glu Val Ser Val
                 395                 400                 405

 His Glu Gln Glu Tyr Gly Leu Gly Ser Ile Ile Ala Gln Asp Glu
                 410                 415                 420

 Ile Tyr Glu Glu Ala Ser Ser Glu Glu Glu Asp Ser Tyr Ser Arg
                 425                 430                 435

 Cys Pro Ala Ile Thr Gln Asn Asn Phe Leu Thr
                 440                 445

<210> 2636
<211> 5620
<212> DNA
<213> Homo sapien

<400> 2636
 aggaggaggt ggcttgaggc aaccatggcg ggaggaatga aagtggcggt 50

 ctcgccggca gttggtcccg ggccctgggg ctcgggagtc gggggcggtg 100

 ggacagtgcg gctactcttg atcctctccg gctgcttggt ctacggcaca 150

 gctgaaactg atgtaaatgt ggtcatgctt caggaatccc aagtttgtga 200

 aaagcgtgcc agccaacaat tctgttacac aaatgtgctt atcccaaaat 250

 ggcatgatat atggacacgg atacagatcc gagtaaatag ttccagattg 300

 gttcgagtca cccaggtgga gaatgaggag aaactgaagg agctagagca 350

 gtttagtatc tggaactttt tttcctcctt tttaaaagag aaattgaatg 400

 acacctatgt taacgtgggt ctatacagca caaaaacctg cctcaaagtt 450

 gagattatag agaaggacac caagtacagt gtcattgtga tccggagatt 500

 tgatcccaaa ctctttcttg ttttccttct tggacttatg ctattttttt 550

 gtggagactt gctgagcaga agtcaaattt tctactactc tactgggatg 600

 actgtgggaa ttgtggcctc tctgctaatc atcattttta tactatctaa 650

 gtttatgcct aagaaaagtc ccatttacgt catcctggtg ggaggctggt 700

 ctttttctct gtacctcatt caactagttt ttaaaaattt acaagagatc 750

 tggaggtgtt actggcagta tcttttaagt tatgtcctca cagttggatt 800

 catgagtttt gcagtatgtt acaagtatgg gcccttggag aatgaacgaa 850

 gtatcaacct gctgacctgg accttgcagc tgatgggcct gtgtttcatg 900

 tattctggca tccagatacc acatattgcc cttgccatta tcatcattgc 950

 tctttgtact aagaacctgg aacaccctat tcagtggctg tacatcacct 1000

 gcagaaaggt gtgtaaggga gcagaaaagc ctgttccccc tcgtctcctg 1050

 acagaagaag aatatcggat acaaggagag gtagaaaccc gaaaggcttt 1100

 agaggagctc cgagaatttt gtaacagtcc agactgctct gcttggaaga 1150

 ctgtttctcg aatccagtct ccaaaaagat ttgctgactt tgtggaaggc 1200

 tcttcccacc tcacgccaaa tgaagtttct gtccatgagc aggagtatgg 1250

 attagggagc attattgccc aggatgaaat ctatgaggaa gcatcctctg 1300

 aggaggagga ctcatattct cggcgtcctg ctatcacaca gaacaacttt 1350

 ctaacctagg tagtggtcag ttatctttac gtggactggc ttggtgcctt 1400

 ggtccatgtt gcatgtgttg tgcaattgct ttcaaccctt tgaaacagag 1450

 tgagatagat agggtagaaa ttctcctact gaaataagag gcctaaaaag 1500

 gcctcccttt ggaaatggga ggtctctatg ggatccctga ggaaggagag 1550

 tggataaagt agtgaatgct gggtagttca cttcccattg gttaagctaa 1600

 cagcccactt ttatgtttcc agagaaattg gatggccaca gctagcatgg 1650

 cattctagct ccttcttgaa agttgattca atcatggcat ttctgtcact 1700

 ggctggctct ccaaagtaag aactgttgtt aagtgcagga atgcttttag 1750

 actataggct gcaacttcca gagagaaatc cacaaatctg agcctccttc 1800

 actccagctt ttatttcagt gactttagaa taattattga tttaactgtt 1850

 ttgggaggaa aatagatttt tattgttttg ttttttaaat gaatgtcttt 1900

 taaaaaacat aacaaactca tgttccagaa ccagcaagtg ctccagagtg 1950

 acacaccccc taggccccta catatttatt aatatggatt atccattaaa 2000

 gccccaggag ctgttgtttt aagctttgat ttagttctca tacatatgat 2050

 agaaagtcct atttgccttt aggaacatgc ctgtaggctc ttctgcaggt 2100

 gagatgtact gggcttttta ttatattcaa ctttcaattc catcttaaaa 2150

 aacatttgta ttcttctctt cccattcttc cttaccctgc ctttgccctt 2200

 tcaggaaggg tcagttccct tacctgtgaa ctatgtatgt tcagagtagc 2250

 attattcctg ctagctagga gaagtcatct tgtttagggg atttggatgc 2300

 tttttatacg ttctccattt tcctgtcatt gggtcatgtt atctttgagt 2350

 tgctatgaaa tcaggaaact gtctcctttt cctttccctt cctttgtcta 2400

 catgctctgt ccattccttt cagccttttc tcaccaccca tactccccca 2450

 aatctgggta atttttaagc cttgaaacta tgtagtttct tgatacacaa 2500

 tttgtagtta tgcagcagcc acaatttgca ttgccaggaa ataggctcca 2550

 ggttatcttc atgcctctgg gtgctcattc agctgtcaag tttccatgaa 2600

 cttacactta tttatgattg cgtttctgac ctgagatgta tgctgcctgt 2650

 tattgcagta gcattagttt cagattcttt tgccattgca aagtacccct 2700

 tataaaccag caatgtcatc tgtgaggaag caaattctca agtgtctgtc 2750

 atttacttgg ttctttttct ttgtggtctt cacccttata ccctggaaaa 2800

 gtctgtaatt accttagcca ggaagataga tggtcatggc aagcgcacag 2850

 caccagactt actggctcac caagatgatg gaaaaaggca gatgattttt 2900

 taaaaagccg taatgactcc tttagaccag ccatttagcg tggtaatttt 2950

 gaaaggccta gctccattgc agacttccaa agggtcagct ctgagactgc 3000

 cctccaggtg ggcagttgat tatttccacc agtgttttcc agagccttaa 3050

 actgtcctaa gtgacaacta cctcagttgg caggaaagag acatatagta 3100

 gaaagtgaaa aatgagcagt atttgggcag atgctatggg ttacagttga 3150

 agggtaaaag gaactttaca ttgggaaacc tttataccct tgtgaattat 3200

 gtacatggta aaatgttctc tctctacaaa gaactattaa aacttctgaa 3250

 atatactatt ttttacctta tttatagaaa ttgagaccta gcatatttaa 3300

 gcataagttt attttaaaaa ataattcaac tagtgcaagt ggtctcagga 3350

 ttctctggag attttggtgc ctcccctact tagggaggtg atagcttgcc 3400

 tataagggtg acttttcctg atcatgtctt tatttcaatg agaaagcact 3450

 gtgaaattgt gaaagattct cctctttctc tgtttaataa acccccatga 3500

 aatatagttt ccatctctag accagttttt tttccaccgt gtttagactt 3550

 gaggtgaata aaatcaaact gttttttact ccctatctgg tagttggaga 3600

 cctgagctgt aggcagtgga gatggcaatt ggttctgcag cctgagagtt 3650

 gctctcacac agtgaaggac ggtgctgctc tggtgtgctg tgtgtccttg 3700

 ccctgcctgc ctgtggctct gcccagatgc ttcagatcct ctgtgttccg 3750

 gagattgctt gacttcaacc ttctttagga gctgctcttg tctccctctt 3800

 ggccacttag tttgctggct cagtcactac ttgaagaccc catttaattt 3850

 ttctctggca gttatagctc ttgtgatttc agtacagtct catctctcag 3900

 accaatctca tcaagaagga ttgaagggat aactatgagg taagctggac 3950

 attggagccg tgtttgctgc cacgtcagcg tcttgctggg tgaatgtcaa 4000

 gccataaatg ggctccaggg ctctggatct catcagcatt ggaaatctat 4050

 tgcctctcat cagtctgacc aaattatgta gagcattaat gtagagactc 4100

 ccattaatgg gaatacaaga ggcagctggc ataaaacatt tctttcactt 4150

 tcctttccca ctcagattgc ttcaagagac caacagaaca cagggatcaa 4200

 aaacaaggaa aatttagcaa cttcattacc ttctaataag taattcctgt 4250

 tagccactgc atcccaccaa aactagttta tttttcccct caaattcatg 4300

 atttttacgt ctgttacaaa gggaattttg ctgatagctc tttgggtccc 4350

 actgttccat tttatgctaa tagattccat tctagggccc agccgtctct 4400

 tgactgatgg tgttcccttt aacccttggc atgtataata gaattttggt 4450

 gaatgaaaga acccaaatag gccagatagt ccccccaggc cctgatatcc 4500

 ataaaaggct tgggaatgca ttatgtaatt gtccttagtc tttttgttgt 4550

 tttagaaaaa aaaaacaaga tgggctcaga tggatgccta cgtaaaaatg 4600

 gttcctagct gtgtactcat aacttttctt tgaattgagt agtgaaagga 4650

 aggaggagga aaggaaatta aatgtccttc tagtattctc tggactcaag 4700

 tctgacatat gagataataa cctatattga aatgccaaga attgtatctg 4750

 aaacaagaga acagtttgac acatttatca tgccttcata ttacatatta 4800

 actgaaacca attaataaac atatgaaata tccattgcac aaggcaaagg 4850

 cacctaaacc ttttgtttct ttttctacat agcagaaatt gatttttttt 4900

 tattttttta ggggaaccta tataattatg acccagtgat gtcttttggt 4950

 gacttaagct tatgaattca ggttacaatt gagttgattc tagatggtta 5000

 ctaccttgaa aaggatgttg gtgccttatg tgacacgagc cagagcctgc 5050

 tgggaataaa caaagcagat tcatgccaac accaactcgt agctttagtg 5100

 gcagatggga gtggtcacag actcccaaaa tgtggggctt tggatttcca 5150

 caccatccca cgtgtgtgtc atcttcctct ttcacactct tgatgataat 5200

 ttgaaaatgg tgaaatcacc tctgaatttg cctatagcat gagcacattc 5250

 ttatgacaac ataacaaata gttcataatg tgaatattag aaactgttac 5300

 agcctgcagt taccataatt ttccatgttt gtggaattga tattgaaata 5350

 gcagggctaa ggaattactg gcaagtttta gcctgtgggt aataccttag 5400

 ggttatttaa atatttgtaa ttttatttaa atgttcatga atgtttgaaa 5450

 ggaacaaaat tatcagggat ggctctttgc catgggtctt attttcaccc 5500

 tcttttctgt aagaaaaaag aacaatgtct taatgtattt ttaaagtttt 5550

 tggtatagtt tctaattcca attttaataa aagttttatg ccaaaaaaaa 5600

 aaaaaaaaaa aaaaaaaaaa 5620

<210> 2637
<211> 452
<212> PRT
<213> Homo sapien

<400> 2637
 Arg Arg Arg Trp Leu Glu Ala Thr Met Ala Gly Gly Met Lys Val
   1               5                  10                  15

 Ala Val Ser Pro Ala Val Gly Pro Gly Pro Trp Gly Ser Gly Val
                  20                  25                  30

 Gly Gly Gly Gly Thr Val Arg Leu Leu Leu Ile Leu Ser Gly Cys
                  35                  40                  45

 Leu Val Tyr Gly Thr Ala Glu Thr Asp Val Asn Val Val Met Leu
                  50                  55                  60

 Gln Glu Ser Gln Val Cys Glu Lys Arg Ala Ser Gln Gln Phe Cys
                  65                  70                  75

 Tyr Thr Asn Val Leu Ile Pro Lys Trp His Asp Ile Trp Thr Arg
                  80                  85                  90

 Ile Gln Ile Arg Val Asn Ser Ser Arg Leu Val Arg Val Thr Gln
                  95                 100                 105

 Val Glu Asn Glu Glu Lys Leu Lys Glu Leu Glu Gln Phe Ser Ile
                 110                 115                 120

 Trp Asn Phe Phe Ser Ser Phe Leu Lys Glu Lys Leu Asn Asp Thr
                 125                 130                 135

 Tyr Val Asn Val Gly Leu Tyr Ser Thr Lys Thr Cys Leu Lys Val
                 140                 145                 150

 Glu Ile Ile Glu Lys Asp Thr Lys Tyr Ser Val Ile Val Ile Arg
                 155                 160                 165

 Arg Phe Asp Pro Lys Leu Phe Leu Val Phe Leu Leu Gly Leu Met
                 170                 175                 180

 Leu Phe Phe Cys Gly Asp Leu Leu Ser Arg Ser Gln Ile Phe Tyr
                 185                 190                 195

 Tyr Ser Thr Gly Met Thr Val Gly Ile Val Ala Ser Leu Leu Ile
                 200                 205                 210

 Ile Ile Phe Ile Leu Ser Lys Phe Met Pro Lys Lys Ser Pro Ile
                 215                 220                 225

 Tyr Val Ile Leu Val Gly Gly Trp Ser Phe Ser Leu Tyr Leu Ile
                 230                 235                 240

 Gln Leu Val Phe Lys Asn Leu Gln Glu Ile Trp Arg Cys Tyr Trp
                 245                 250                 255

 Gln Tyr Leu Leu Ser Tyr Val Leu Thr Val Gly Phe Met Ser Phe
                 260                 265                 270

 Ala Val Cys Tyr Lys Tyr Gly Pro Leu Glu Asn Glu Arg Ser Ile
                 275                 280                 285

 Asn Leu Leu Thr Trp Thr Leu Gln Leu Met Gly Leu Cys Phe Met
                 290                 295                 300

 Tyr Ser Gly Ile Gln Ile Pro His Ile Ala Leu Ala Ile Ile Ile
                 305                 310                 315

 Ile Ala Leu Cys Thr Lys Asn Leu Glu His Pro Ile Gln Trp Leu
                 320                 325                 330

 Tyr Ile Thr Cys Arg Lys Val Cys Lys Gly Ala Glu Lys Pro Val
                 335                 340                 345

 Pro Pro Arg Leu Leu Thr Glu Glu Glu Tyr Arg Ile Gln Gly Glu
                 350                 355                 360

 Val Glu Thr Arg Lys Ala Leu Glu Glu Leu Arg Glu Phe Cys Asn
                 365                 370                 375

 Ser Pro Asp Cys Ser Ala Trp Lys Thr Val Ser Arg Ile Gln Ser
                 380                 385                 390

 Pro Lys Arg Phe Ala Asp Phe Val Glu Gly Ser Ser His Leu Thr
                 395                 400                 405

 Pro Asn Glu Val Ser Val His Glu Gln Glu Tyr Gly Leu Gly Ser
                 410                 415                 420

 Ile Ile Ala Gln Asp Glu Ile Tyr Glu Glu Ala Ser Ser Glu Glu
                 425                 430                 435

 Glu Asp Ser Tyr Ser Arg Arg Pro Ala Ile Thr Gln Asn Asn Phe
                 440                 445                 450

 Leu Thr


<210> 2638
<211> 3269
<212> DNA
<213> Homo sapien

<400> 2638
 ggtcgtctcg ggtgaggagg tcgcgccgga agtggctcta gccgtggcgc 50

 ttcggcgtag taaggagcct gcaacagagt tttgttgttt agggggcgcg 100

 gcaccgcacc gctcccttca ccttgcagca gccatggcga aaggcagagt 150

 cgccgaacga tcgcagttgg gcgctcacca cacgaccccc gtgggggacg 200

 gggcagcggg gacgcggggt ctcgcggcgc ctggcagcag agaccaccag 250

 aaggaaaaat cctgggtaga agctggatca gcaagaatgt cactccttat 300

 attggtgtcc attttcttat ctgcagcttt tgttatgttt ttggtatata 350

 aaaattttcc tcagcttagt gaagaagaaa gagtgaatat gaaggttccc 400

 agagatatgg atgatgccaa ggctctagga aaagttttat ccaaatacaa 450

 ggacaccttt tatgttcaag tacttgtagc ttattttgct acatatattt 500

 tcttgcaaac atttgctatt ccaggctcta tatttctcag tatactctca 550

 gggtttcttt atccctttcc actagcctta tttcttgttt gtttgtgttc 600

 tggacttggt gcctctttct gttatatgct ttcctattta gttgggagac 650

 cagttgtata caaataccta acagagaaag cagtaaaatg gtcacagcag 700

 gttgaacgtc atagagaaca tctcattaac tacattatat ttttgagaat 750

 aacaccattt ctgcctaatt ggtttattaa tatcacatct cctgtgataa 800

 acgtgccatt gaaagttttt tttattggta cttttctagg tgttgcacct 850

 ccttcttttg tagccattaa ggcaggaaca acactgtatc aacttacaac 900

 agcaggagaa gctgtttcct ggaactcaat atttattctg atgatcttgg 950

 ctgttctttc tattctgcca gccatcttcc aaaaaaaact aaagcagaaa 1000

 tttgagtaaa aataatcatc tgatttttag ttttgctgtc atcaccatct 1050

 caggattaac agatgcatcc atttatgttt taaaatcacc tcttcagtaa 1100

 ttaaacaagg aatttgtaaa ataaaatttc ctatcagata gttaaagtaa 1150

 tacatttaag tgacaagggg agaagaaagt aaaaatggaa attggtatac 1200

 tgtgaaaagt gctatcaata gttaaggtag acatcttaga catcttataa 1250

 attattatac caagggtagc tgtagataat agtagtgtgg taggaaattg 1300

 ttgatccagc taattcattc aatttaattg aatatttttt atctttaata 1350

 actaaaatag atatttttaa attctagatt ttttaaagta gtgttgcagg 1400

 ttttgttaat gttaggcttt tttcagagca taaactggaa aacttaaaaa 1450

 gagatttaca ttttcttcct cttttttttt tttttttttt ctgttttgag 1500

 acggagtcta gctctgccgc ccaggctgga gtgcagtggc gcgatctccg 1550

 ctcattgcaa gctccacctc ctgggttcac gccattctcc tgtctcagcc 1600

 tcctgagtag ctgggactac aggcgcccgc caccatgccc agctaatttt 1650

 tttgtatttt tagtagagac ggggtttcac cgtgttagcc aggatggtct 1700

 cgatctcctg acctcgtgat ctgcccgcct tggcctccca aagtgctggg 1750

 attacaggca tgagccaccg cgcctggccc attttcttcc tcttttgagg 1800

 taatggattt gtttggagat ggcatgttag tagacgactg aatatggaaa 1850

 ggatatcgag ttatctattt tgttaatttt atttttgttt tttatcatct 1900

 agatttttat catggattag tctgaaattt aaagttctgg ccagtcggtt 1950

 ttctttcatc ttgtagtttt tacagtattt ccactgtgca tatgcaaaat 2000

 gggtattaca taactgtatc atatttggta ttgataattt tttttttttt 2050

 tgagacggag tcttgctgtt gcccaggctg gagtggagtg cgtggtgtga 2100

 tctcggctca ctgcaaactc cgcctcctgg gttcaagcga ttctcctggc 2150

 ccagcctcct gagtagctgg gattacaggt gtgtgccacc atgcccagct 2200

 aatttttgtg tttttagtag agacggggtt tcaccatgtt ggccgggctg 2250

 gtcttgaact cctgacctca ggctatatgc ccacttccac ctcccaaagt 2300

 gctgggatta caggcatgag ccactgtgcc cagcctggta ttgataattt 2350

 atattcagat aatttgttat ggctctttaa tatcccacaa ggggctctaa 2400

 aaagcaaaca ttcaagagta tgtagttttt agacattaag ttaattattt 2450

 taaacagtga cagcaaaaca caagtgatta aatatagttt atttgttcca 2500

 atgactaaat tttacctcat ttattaatct ggtcattaag gaatatattt 2550

 aataatatta tgtaattatt ctttttatgc atgatacacc tagaaaaatg 2600

 ccttttgttt ctattgatgg ctttgttgtt tggagctact tttgattact 2650

 tattgcagtt tcccaattta gtctttactt tatctaactc acaaagtaaa 2700

 attaactgat cacatggcaa ctactgtatt taaatagttc tggaaaaatg 2750

 aaagtgcttt ttgctgcttg gtaaatgggt aatgcccttg attccttgac 2800

 tgtaggacat agctgatcta aagtactctg tcagttttac cttcacccat 2850

 gactgtcatt agttgtcaaa gttgaaaagt actttagctg tgagaaatcc 2900

 ttgtatgttt ttattataag aggtataatc atcctcaaag cctgttttta 2950

 ttacatgatg tggactgatt attttttcta tcacagtgtt aacagatgga 3000

 ttttattgta aatacaaaga aaacatattg attattgtag tattcttatg 3050

 tcacctggcc ttttgcgtga ggattattta ttatttctag caaggctttc 3100

 ttcctttctt attgcccaga gactgactga tacatctttt gttattttta 3150

 cacataaatt aaacatagcc tttttggaca aattcactaa atattaatgt 3200

 ataaaatgta attgagtaaa tttttatcag aattttaaaa ataaaagagc 3250

 ttagactcag taggaactc 3269

<210> 2639
<211> 335
<212> PRT
<213> Homo sapien

<400> 2639
 Val Val Ser Gly Glu Glu Val Ala Pro Glu Val Ala Leu Ala Val
   1               5                  10                  15

 Ala Leu Arg Arg Ser Lys Glu Pro Ala Thr Glu Phe Cys Cys Leu
                  20                  25                  30

 Gly Gly Ala Ala Pro His Arg Ser Leu His Leu Ala Ala Ala Met
                  35                  40                  45

 Ala Lys Gly Arg Val Ala Glu Arg Ser Gln Leu Gly Ala His His
                  50                  55                  60

 Thr Thr Pro Val Gly Asp Gly Ala Ala Gly Thr Arg Gly Leu Ala
                  65                  70                  75

 Ala Pro Gly Ser Arg Asp His Gln Lys Glu Lys Ser Trp Val Glu
                  80                  85                  90

 Ala Gly Ser Ala Arg Met Ser Leu Leu Ile Leu Val Ser Ile Phe
                  95                 100                 105

 Leu Ser Ala Ala Phe Val Met Phe Leu Val Tyr Lys Asn Phe Pro
                 110                 115                 120

 Gln Leu Ser Glu Glu Glu Arg Val Asn Met Lys Val Pro Arg Asp
                 125                 130                 135

 Met Asp Asp Ala Lys Ala Leu Gly Lys Val Leu Ser Lys Tyr Lys
                 140                 145                 150

 Asp Thr Phe Tyr Val Gln Val Leu Val Ala Tyr Phe Ala Thr Tyr
                 155                 160                 165

 Ile Phe Leu Gln Thr Phe Ala Ile Pro Gly Ser Ile Phe Leu Ser
                 170                 175                 180

 Ile Leu Ser Gly Phe Leu Tyr Pro Phe Pro Leu Ala Leu Phe Leu
                 185                 190                 195

 Val Cys Leu Cys Ser Gly Leu Gly Ala Ser Phe Cys Tyr Met Leu
                 200                 205                 210

 Ser Tyr Leu Val Gly Arg Pro Val Val Tyr Lys Tyr Leu Thr Glu
                 215                 220                 225

 Lys Ala Val Lys Trp Ser Gln Gln Val Glu Arg His Arg Glu His
                 230                 235                 240

 Leu Ile Asn Tyr Ile Ile Phe Leu Arg Ile Thr Pro Phe Leu Pro
                 245                 250                 255

 Asn Trp Phe Ile Asn Ile Thr Ser Pro Val Ile Asn Val Pro Leu
                 260                 265                 270

 Lys Val Phe Phe Ile Gly Thr Phe Leu Gly Val Ala Pro Pro Ser
                 275                 280                 285

 Phe Val Ala Ile Lys Ala Gly Thr Thr Leu Tyr Gln Leu Thr Thr
                 290                 295                 300

 Ala Gly Glu Ala Val Ser Trp Asn Ser Ile Phe Ile Leu Met Ile
                 305                 310                 315

 Leu Ala Val Leu Ser Ile Leu Pro Ala Ile Phe Gln Lys Lys Leu
                 320                 325                 330

 Lys Gln Lys Phe Glu
                 335

<210> 2640
<211> 1134
<212> DNA
<213> Homo sapien

<400> 2640
 aaaaactcct ttttgcaata gaagagacag agggatttgg acaagaatga 50

 atgtggcttc ttattttgga ggagctcttg catttaaata ccccagccaa 100

 gaaagattgc acagatagtg tatataagct gttcattctg tacagtgaat 150

 tttccgaacc tctcaaagta tgttttccgt tcttccacag aaatatgcaa 200

 aacagttcat ccttttctac tttatttatt gttcccttga aatgactgac 250

 caggaaaaag atcatcctta aattttgaag caagtgagag actttattaa 300

 aaatacatat atatctatat aaacatagat gatagtggct ctagttttat 350

 agagctccaa gtgtattaaa catgacagcc attcattcat aaagatctgg 400

 atttgcttta ccttgttaat attatctagg ggaaaaagtg caaattgctc 450

 catgttctac tctcccttat gtaacatctc ctgagggtgt ttagttgcat 500

 ggctgttcag aaaggtatta agggcttagg ccaaatctta ctttgagtat 550

 gttaaaaaaa aaaaaaatgc tgctggcttt tctgaagaca ggtgcttgaa 600

 cttgtcagtt tgttttaaat aaatacaata gttgaaaatt tttctctgtt 650

 acatcagtaa tattgttaaa gtaatggata gaaccataac ttacacatga 700

 aagtcatata ctagatccaa tactatttag tttattatcg aaattggaag 750

 gattcattga gcagcataga agtttgttta catgttactt tgagatgcta 800

 ggtatttgtg gaattaaaaa gaatcaggct cttttgtact ttgtttttaa 850

 atctgtgatg cttttcaaat ttaattcata ataaattgat gcaatttcat 900

 acttaggaac atacaaaagg taatgtaaac tctgccactt ttttgtgttc 950

 aaaattttgg tttttatgaa gccagatgga ttgaagagtt acataagcat 1000

 ttgaatgctc taatataagg ctaatgattt tctgttagtg tttgaatatc 1050

 ttcattcctc tcaaattcat aacagttcta tttaactgaa ttaaataacc 1100

 atatgaaaaa tcgaaaaaaa aaaaaaaaaa gaaa 1134

<210> 2641
<211> 38
<212> PRT
<213> Homo sapien

<400> 2641
 Lys Thr Pro Phe Cys Asn Arg Arg Asp Arg Gly Ile Trp Thr Arg
   1               5                  10                  15

 Met Asn Val Ala Ser Tyr Phe Gly Gly Ala Leu Ala Phe Lys Tyr
                  20                  25                  30

 Pro Ser Gln Glu Arg Leu His Arg
                  35

<210> 2642
<211> 9175
<212> DNA
<213> Homo sapien

<400> 2642
 tatgtttagt cccatatgct cttcctgaat cttgccactg cccatcaaga 50

 gatagaatac atttcccctc cccttgaaca tggaagcaac caagctttaa 100

 gaagcacagc tttggagaca ctccatgagt ctgcactgct ttcaggggaa 150

 ctagcactta agaccttgtg taacaaaatg gacactgggg acacagctct 200

 aggacaaaaa gctacctcaa ggtctggaga aactgataaa gcatcaggta 250

 gatggagaca ggaacaatca gctgttatta agatgagcac ttttggcagt 300

 catgaaggac agcggcaacc acaaatagag cctgagcaaa tcggaaacac 350

 agcatcagca caactgtttg gttctgggaa actggcctcc cctagtgaag 400

 tggtgcagca agtcgcagag aagcaatatc caccgcatcg tccgagtcct 450

 tactcatgcc aacactcact ctctttccct cagcactcat tgccacaggg 500

 ggtcatgcac agcaccaagc cacatcagag cctcgaaggt cctccgtggc 550

 ttttccctgg ccctttgcca tccgttgcct ctgaggactt atttcctttt 600

 cctatacatg gccacagtgg tggttatcct agaaaaaaga tttcaagtct 650

 gaaccctgct tatagccaat actcccagaa aagtattgaa caggcagaag 700

 aggctcacaa gaaagagcac aaacccaaaa agcctggcaa gtacatttgc 750

 ccttactgca gcagagcgtg tgccaaacct agtgtactga aaaaacacat 800

 caggtcccat actggggagc ggccatatcc atgtatacct tgtggtttct 850

 ctttcaagac aaagagcaat ttgtacaagc acaggaagtc acatgcccat 900

 gcaattaagg caggattagt acctttcaca gagtcagctg tatctaaatt 950

 ggacctagag gctggtttta ttgatgtaga agcagaaata cattcagatg 1000

 gtgaacagag tacagacaca gatgaggaga gttctttatt tgccgaggct 1050

 tctgacaaaa tgagtcctgg tccacccatc ccactggaca ttgccagcag 1100

 aggcggctat catgggtcat tggaagaatc attgggaggt ccaatgaagg 1150

 tgccgatttt gattatccct aaaagtggga ttcctctccc taatgaaagc 1200

 tctcagtata ttggccctga tatgctacca aatccatctt taaatactaa 1250

 ggctgatgat tcgcacacag tcaaacagaa acttgcacta agactgtcag 1300

 agaaaaaagg acaagattct gagccatcgc tcaaccttct gagcccgcac 1350

 agtaaaggaa gcactgattc tggttacttt tctcgctcag aaagtgctga 1400

 gcagcaaata agccctccca acacaaatgc aaagtcttat gaagaaatca 1450

 tctttggaaa atactgtcgg cttagtccga gaaatgcact cagtgttaca 1500

 accacaagtc aggagcgtgc cgcaatgggt aggaagggca taatggaacc 1550

 attacctcac gttaacacca ggttagatgt caagatgttt gaagatcctg 1600

 tttcacagct gatcccaagc aagggagatg tcgaccccag tcaaacgagc 1650

 atgctgaaat ccactaagtt caacagtgag tccagacaac cccagattat 1700

 tccatcatct atcaggaacg aaggaaaact ttatccagca aacttccaag 1750

 gcagcaaccc ggttctctta gaagctcctg tagactcttc accccttatt 1800

 agaagcaact cagtgccaac ttcttcagca actaatctaa ctattcctcc 1850

 ttctttgaga ggaagtcact catttgatga aaggatgact ggttccgacg 1900

 atgtattcta tccagggacc gtgggcatac cccctcagcg catgctaaga 1950

 agacaagcgg catttgagct gccttcggta caggagggcc acgtggaagt 2000

 cgagcaccat ggcaggatgt tgaagggtat cagcagttca tccctgaagg 2050

 aaaagaaatt gtctcctggg gacagggttg ggtatgacta tgatgtctgt 2100

 cggaaaccct ataagaagtg ggaggactct gaaacaccaa agcaaaacta 2150

 cagggacatt tcctgcttga gttctttaaa gcatggtgga gaatatttca 2200

 tggatcccgt ggtgccattg cagggagtac caagcatgtt tggaactacc 2250

 tgtgaaaaca ggaaacgccg gaaagagaag agcgtagggg atgaagagga 2300

 cacgcccatg atctgcagca gcattgtaag cactcctgtg ggcatcatgg 2350

 cttccgatta tgaccccaaa ctgcagatgc aggaaggagt caggagtgga 2400

 tttgccatgg ctggacacga aaacctttct catggtcaca cggaacgctt 2450

 tgacccatgt cggccccaac tgcagcctgg aagtccatct cttgtgtcag 2500

 aggagtcacc ttcagccatt gattcagaca agatgtcaga cctagggggc 2550

 aggaaacctc ctggaaatgt gatttctgtg attcagcaca ccaactcact 2600

 gagccgaccc aattcatttg aaaggtctga gtcagccgaa cttgtggctt 2650

 gcacacagga taaagcccct tccccttcag agacttgtga cagtgagatt 2700

 tcagaagccc cagtgagtcc tgagtgggct ccacctgggg atggtgcaga 2750

 aagtgggggg aaaccctctc catctcagca ggtgcagcag cagtcctatc 2800

 acacacagcc caggctagtt cggcaacaca acatccaggt tcctgagatt 2850

 cgagtgaccg aggagcctga taaacctgag aaggagaagg aagcccagag 2900

 caaagagcca gagaagcctg tggaagaatt tcagtggccc cagagaagtg 2950

 agaccctttc ccagctcccc gcggagaagt tgcctcccaa aaagaagcgt 3000

 ctgcgacttg cagatatgga gcactcctca ggggagtcca gctttgaatc 3050

 cacaggcaca ggcctctccc gcagccccag ccaagaaagc aacttgtccc 3100

 acagctccag tttctccatg tcttttgaaa gagaagaaac cagtaagctt 3150

 tctgcacttc ctaagcagga tgagtttggg aagcattcag agtttctgac 3200

 tgtccctgct ggttcatact cattgtctgt cccaggccat caccaccaga 3250

 aagagatgcg acgctgctca tcagagcaga tgccttgtcc tcacccagcg 3300

 gaagtcccag aagttcggag caaatcattt gattatggga atctgtccca 3350

 tgctcctgtg tcgggagcag cagcctccac ggtatcaccg tccagggaga 3400

 ggaagaaatg ctttctggtg cggcaagctt ccttcagtgg ctccccagaa 3450

 atctcccagg gcgaggttgg catggatcag agcgtgaagc aagagcagct 3500

 ggagcacctg catgctggcc tccggtccgg gtggcaccat ggcccgcctg 3550

 ctgtgctgcc tcctcttcag caagaggacc cagggaagca ggtggcgggt 3600

 ccttgtcccc cgctgagctc ggggccactg cacctggccc agccacagat 3650

 catgcacatg gacagtcagg aatctttgag aaatcccttg atccaaccaa 3700

 catcctatat gacaagcaag cacttacctg aacagccaca cttatttcca 3750

 catcaagaga caattccatt ttctccaatc cagaatgcct tgtttcagtt 3800

 tcagtatcct acagtttgta tggttcattt accagctcag cagcctccct 3850

 ggtggcaggc acatttccca catccctttg ctcagcaccc tcagaagagc 3900

 tatggcaagc cctcttttca gacagaaatc cattcgagct atcccttaga 3950

 gcatgtggca gagcacactg gaaagaaacc tgctgagtat gcacacacga 4000

 aagagcagac ctacccatgt tattcaggag catcagggct acacccaaag 4050

 aaccttcttc caaagtttcc atcagaccag agcagtaagt caactgaaac 4100

 gccctctgag caggttcttc aagaagattt tgcctcggca aatgctgggt 4150

 ctttgcagtc cctcccagga acagtggttc ctgttcggat ccagacgcac 4200

 gtaccatcct atggaagtgt catgtacaca agcatttctc agatacttgg 4250

 gcagaatagc cctgccattg tcatatgcaa agtcgatgag aatatgaccc 4300

 aaaggacact ggtcaccaac gcagccatgc aagggatagg attcaacatt 4350

 gcccaggtgc tggggcagca tgcgggcttg gagaagtacc ccatttggaa 4400

 agcacctcag actttgcccc tcggcttaga atcctccatc cccttgtgtt 4450

 taccttccac ctctgacagc gtggccaccc tgggaggtag caagcgaatg 4500

 ctttctccag ccagtagctt ggagctcttc atggaaacca agcagcagaa 4550

 aagggtcaaa gaagaaaaga tgtacggaca gattgtggag gagcttagtg 4600

 ctgtggagct gaccaactca gacatcaaaa aggacctctc ccgcccccag 4650

 aaaccccagc tggttcgaca aggatgtgct tctgagccaa aagatggctt 4700

 gcagtcaggg tcatcttcct tctcctcgct gtcgccctcc tcatctcaag 4750

 actatccttc tgttagcccg tcttccaggg agccattccc gcccagcaag 4800

 gagatgcttt ccggttcccg ggcaccactt ccggggcaga agtccagtgg 4850

 gccttctgaa agcaaagaat cttcagatga attagatatc gatgagacgg 4900

 catcggacat gagcatgagc ccacagagtt cttcattacc agcaggagat 4950

 ggtcagctgg aagaggaagg gaagggccac aagcggcctg ttggcatgct 5000

 ggtccgcatg gcctctgccc ccagcgggaa cgtggcagac tcaactcttc 5050

 ttctcacgga catggcagat ttccagcaga ttcttcagtt ccccagtctg 5100

 cggacaacaa ctactgtgag ttggtgcttc ttgaattata caaaacccaa 5150

 ttatgtgcaa caggccacct tcaaatcctc ggtttatgct tcatggtgca 5200

 ttagttcctg taatccaaac ccatcaggat tgaacaccaa gaccacgctg 5250

 gctcttctga ggtccaagca aaaaatcact gcagaaattt atactctggc 5300

 tgctatgcat aggcctggaa ccggcaagct tacatcatca agtgcttgga 5350

 agcagtttac tcagatgaaa cctgatgcgt cctttttatt tggcagcaaa 5400

 ctagaaagga aactagtggg aaatatctta aaggaaagag ggaaaggaga 5450

 tattcatgga gataaagata ttggatccaa acaaactgag ccaatccgaa 5500

 ttaaaatatt tgaaggaggg tacaaatcga atgaagatta tgtatatgtc 5550

 agaggacgtg gccggggaaa gtacatttgt gaagaatgtg ggattcgctg 5600

 taagaagcca agcatgctca aaaaacacat ccgtacccat actgatgttc 5650

 ggccttatgt atgcaagtta tgtaactttg ccttcaaaac gaaaggaaac 5700

 ctaacgaagc atatgaaatc taaagcacac atgaaaaaat gcctggaatt 5750

 gggagtctca atgacatcgg tggatgatac agaaactgag gaagcagaaa 5800

 atttggaaga tttgcacaaa gcagcagaga agcatagcat gtccagcatt 5850

 tcaactgatc atcagttctc cgatgctgag gaatcagatg gtgaggatgg 5900

 agatgataat gatgatgatg atgaagatga agatgacttt gacgaccagg 5950

 gagatttaac accaaaaaca agatcaagaa gcaccagtcc tcagcctcct 6000

 agattctcct ccttgcctgt gaatgttggc gccgtacccc acggggttcc 6050

 ttcagatagt tccctgggac attcttcgtt gatcagctat ttggttactt 6100

 tgccaagtat tcgagttact cagcttatga cacccagtga ttcatgtgaa 6150

 gatacccaga tgacagaata ccagaggcta ttccagagca aaagtacgga 6200

 ctcagaacca gacaaagaca gattggacat acctagttgt atggatgagg 6250

 agtgcatgct accttcagag ccaagctcct ctcccaggga cttctcaccc 6300

 tcaagccacc attcctctcc aggatatgat tcttcaccct gtcgagataa 6350

 ttcaccaaag aggtatctga tacccaaagg agatttatct cccaggagac 6400

 atttatcacc taggagagat ctgtcaccca tgagacatct ttcaccaaca 6450

 aaggaagctg cattgagaag agagatgtcc caaagagatg tttcaccaag 6500

 aaggcatttg tctccaagga ggccagtgtc tcctgggaaa gatatcacag 6550

 caagaagaga cctctcccct agaagagaga gaagatacat gaccacaata 6600

 agagcgccat ctcccagaag ggctttatac cataacccac cattgtccat 6650

 gggacagtat ttgcaagcag agccaattgt attggggcct cctaatttaa 6700

 gaagaggatt acctcaggtt ccttacttca gtctctatgg agaccaagaa 6750

 ggtgcttatg aacatccagg ctccagcctt ttccctgagg gtcctaatga 6800

 ctatgtcttc agtcatcttc cactccactc tcagcaacaa gtgcgagccc 6850

 ctatccccat ggtgcccgtt ggtgggatcc agatggttca ctccatgccg 6900

 ccagcccttt ccagtttaca tccttcaccc acattgcccc tgccaatgga 6950

 gggctttgag gagaagaaag gcgcgtcagg ggagtccttc tccaaggacc 7000

 cctatgtgct ttctaagcag catgagaagc gaggtcctca cgctttgcag 7050

 tcatctggtc cgcctagcac tccctcctct cctcggctgt tgatgaaaca 7100

 gagcacttcg gaagacagcc taaacgcaac agagcgggaa caggaggaaa 7150

 atatacagac ttgtacaaaa gccattgcct ctctccggat tgccacggaa 7200

 gaggcagctc tgctcgggcc agatcagcca gcgcgggtgc aggagcccca 7250

 ccagaacccc ctgggaagtg cacatgttag cattagacac tttagtagac 7300

 ctgagccagg tcagccctgt acctcagcca cccaccctga cttgcatgat 7350

 ggtgaaaagg acaattttgg tacatcacag actccattag ctcactccac 7400

 gttttacagc aagagttgtg tggatgacaa gcagttggac tttcacagca 7450

 gcaaggaatt atcttcaagc acagaggaaa gcaaagatcc ttcatcagaa 7500

 aagagtcagc tacattgatc tatgatgcat ggagactttc atttccacat 7550

 tttcccattt ttttgttttt gtttttctag aaatggaggt aatccagttt 7600

 atagcatgcc tgtcctaagt tacagtagtt tgctattata tatacttttg 7650

 ttatatcaaa agaattaggt aaattaacaa gtcatcatga gcctgaccaa 7700

 aacaaaattt gaaattaacc tattgggtct ggtactttta aaattgtaca 7750

 gatgtttgtg ccttttcttt actttgctta tattcttata agcatttttt 7800

 agcagtaatt tgtacatatt ttagaatttg tgtatctgct ttgtaataaa 7850

 tgtaatttct ttcctttttt ggacacttgg atctaaatga tgtaaagcaa 7900

 aacagcatca atatatatgt gaggttgcac taaaacatat ttttatatga 7950

 ttaaaactga acagctttta tgtacagctc tgattctgta atactaatat 8000

 ttatttactt tgtttcataa attgtacatt ttttcttaat gttgtggatt 8050

 gcttttctat gtgaagcatg ggatttactg ttgcgtaact agaacaaaaa 8100

 tgtacattgt aaacaagata tttaaactag agtatcttat tctgcactta 8150

 tgcattagtt aaaaaaagat aaaggatgta tcagtcagtt cttaactctt 8200

 gtatattttt ttgtctcttg tttgctggat tgactataac ttaagtgctg 8250

 attgtgattt taaaatgata gtaccgtaaa gcattaaagt aaacaatgtg 8300

 ctattgtgag ttttttcaaa gctttataaa tcagttataa ataatattaa 8350

 aagtatttgg tcttatgtga acatgttgat ctatatactc atctaaaaat 8400

 atgggaaaac attccacccc atgtaaatat gtacaagtgc atcactggta 8450

 caattttatg taactcagtt ggacactagg ttgccacaga cctatgctag 8500

 gtgtctttaa aaaattaagg tgacaaagca catgggactg tgtagagctt 8550

 ggttatcggc cggcccggtg gcttggcagg cagtctgtcg ctgctcatgg 8600

 agaagacctg ggcttagcaa tctccttagt tcttgctaca caggatggtg 8650

 actggaacta aggctacaca gagggtcgca cttggactct gagggttggg 8700

 tgtggaaggg ggaaaagggg atggagacct gctccccagc tcttcctgtc 8750

 agccggttta catgggaaca gggttaacat ctgtgttagg ggaggtcacc 8800

 ttaccctttt tcatagggga agagtgtcac actcctggct atctcagggg 8850

 gaatggggaa aagaatcttt caagggcaaa gaactcgtgg gaggatgtct 8900

 gttgtatgta atactcacaa tggcttttgg ttagtgttga aggtgggaag 8950

 agcatttgta ggtccagaag agtgaaagag agggaggggt gcagcaacat 9000

 gtgcacaggc acgcacatgt gtgcacgcac acatacaatc tgggttatct 9050

 ttgtgctata tagtggatta taattctgtg aaaccaagtt tgtatattga 9100

 attacattaa ggagtgttct ttaaaaagag aaataaatat acaattacat 9150

 gcttaaaaaa aaaaaaaaaa aaaaa 9175

<210> 2643
<211> 2000
<212> PRT
<213> Homo sapien

<400> 2643
 Met Leu Phe Leu Asn Leu Ala Thr Ala His Gln Glu Ile Glu Tyr
   1               5                  10                  15

 Ile Ser Pro Pro Leu Glu His Gly Ser Asn Gln Ala Leu Arg Ser
                  20                  25                  30

 Thr Ala Leu Glu Thr Leu His Glu Ser Ala Leu Leu Ser Gly Glu
                  35                  40                  45

 Leu Ala Leu Lys Thr Leu Cys Asn Lys Met Asp Thr Gly Asp Thr
                  50                  55                  60

 Ala Leu Gly Gln Lys Ala Thr Ser Arg Ser Gly Glu Thr Asp Lys
                  65                  70                  75

 Ala Ser Gly Arg Trp Arg Gln Glu Gln Ser Ala Val Ile Lys Met
                  80                  85                  90

 Ser Thr Phe Gly Ser His Glu Gly Gln Arg Gln Pro Gln Ile Glu
                  95                 100                 105

 Pro Glu Gln Ile Gly Asn Thr Ala Ser Ala Gln Leu Phe Gly Ser
                 110                 115                 120

 Gly Lys Leu Ala Ser Pro Ser Glu Val Val Gln Gln Val Ala Glu
                 125                 130                 135

 Lys Gln Tyr Pro Pro His Arg Pro Ser Pro Tyr Ser Cys Gln His
                 140                 145                 150

 Ser Leu Ser Phe Pro Gln His Ser Leu Pro Gln Gly Val Met His
                 155                 160                 165

 Ser Thr Lys Pro His Gln Ser Leu Glu Gly Pro Pro Trp Leu Phe
                 170                 175                 180

 Pro Gly Pro Leu Pro Ser Val Ala Ser Glu Asp Leu Phe Pro Phe
                 185                 190                 195

 Pro Ile His Gly His Ser Gly Gly Tyr Pro Arg Lys Lys Ile Ser
                 200                 205                 210

 Ser Leu Asn Pro Ala Tyr Ser Gln Tyr Ser Gln Lys Ser Ile Glu
                 215                 220                 225

 Gln Ala Glu Glu Ala His Lys Lys Glu His Lys Pro Lys Lys Pro
                 230                 235                 240

 Gly Lys Tyr Ile Cys Pro Tyr Cys Ser Arg Ala Cys Ala Lys Pro
                 245                 250                 255

 Ser Val Leu Lys Lys His Ile Arg Ser His Thr Gly Glu Arg Pro
                 260                 265                 270

 Tyr Pro Cys Ile Pro Cys Gly Phe Ser Phe Lys Thr Lys Ser Asn
                 275                 280                 285

 Leu Tyr Lys His Arg Lys Ser His Ala His Ala Ile Lys Ala Gly
                 290                 295                 300

 Leu Val Pro Phe Thr Glu Ser Ala Val Ser Lys Leu Asp Leu Glu
                 305                 310                 315

 Ala Gly Phe Ile Asp Val Glu Ala Glu Ile His Ser Asp Gly Glu
                 320                 325                 330

 Gln Ser Thr Asp Thr Asp Glu Glu Ser Ser Leu Phe Ala Glu Ala
                 335                 340                 345

 Ser Asp Lys Met Ser Pro Gly Pro Pro Ile Pro Leu Asp Ile Ala
                 350                 355                 360

 Ser Arg Gly Gly Tyr His Gly Ser Leu Glu Glu Ser Leu Gly Gly
                 365                 370                 375

 Pro Met Lys Val Pro Ile Leu Ile Ile Pro Lys Ser Gly Ile Pro
                 380                 385                 390

 Leu Pro Asn Glu Ser Ser Gln Tyr Ile Gly Pro Asp Met Leu Pro
                 395                 400                 405

 Asn Pro Ser Leu Asn Thr Lys Ala Asp Asp Ser His Thr Val Lys
                 410                 415                 420

 Gln Lys Leu Ala Leu Arg Leu Ser Glu Lys Lys Gly Gln Asp Ser
                 425                 430                 435

 Glu Pro Ser Leu Asn Leu Leu Ser Pro His Ser Lys Gly Ser Thr
                 440                 445                 450

 Asp Ser Gly Tyr Phe Ser Arg Ser Glu Ser Ala Glu Gln Gln Ile
                 455                 460                 465

 Ser Pro Pro Asn Thr Asn Ala Lys Ser Tyr Glu Glu Ile Ile Phe
                 470                 475                 480

 Gly Lys Tyr Cys Arg Leu Ser Pro Arg Asn Ala Leu Ser Val Thr
                 485                 490                 495

 Thr Thr Ser Gln Glu Arg Ala Ala Met Gly Arg Lys Gly Ile Met
                 500                 505                 510

 Glu Pro Leu Pro His Val Asn Thr Arg Leu Asp Val Lys Met Phe
                 515                 520                 525

 Glu Asp Pro Val Ser Gln Leu Ile Pro Ser Lys Gly Asp Val Asp
                 530                 535                 540

 Pro Ser Gln Thr Ser Met Leu Lys Ser Thr Lys Phe Asn Ser Glu
                 545                 550                 555

 Ser Arg Gln Pro Gln Ile Ile Pro Ser Ser Ile Arg Asn Glu Gly
                 560                 565                 570

 Lys Leu Tyr Pro Ala Asn Phe Gln Gly Ser Asn Pro Val Leu Leu
                 575                 580                 585

 Glu Ala Pro Val Asp Ser Ser Pro Leu Ile Arg Ser Asn Ser Val
                 590                 595                 600

 Pro Thr Ser Ser Ala Thr Asn Leu Thr Ile Pro Pro Ser Leu Arg
                 605                 610                 615

 Gly Ser His Ser Phe Asp Glu Arg Met Thr Gly Ser Asp Asp Val
                 620                 625                 630

 Phe Tyr Pro Gly Thr Val Gly Ile Pro Pro Gln Arg Met Leu Arg
                 635                 640                 645

 Arg Gln Ala Ala Phe Glu Leu Pro Ser Val Gln Glu Gly His Val
                 650                 655                 660

 Glu Val Glu His His Gly Arg Met Leu Lys Gly Ile Ser Ser Ser
                 665                 670                 675

 Ser Leu Lys Glu Lys Lys Leu Ser Pro Gly Asp Arg Val Gly Tyr
                 680                 685                 690

 Asp Tyr Asp Val Cys Arg Lys Pro Tyr Lys Lys Trp Glu Asp Ser
                 695                 700                 705

 Glu Thr Pro Lys Gln Asn Tyr Arg Asp Ile Ser Cys Leu Ser Ser
                 710                 715                 720

 Leu Lys His Gly Gly Glu Tyr Phe Met Asp Pro Val Val Pro Leu
                 725                 730                 735

 Gln Gly Val Pro Ser Met Phe Gly Thr Thr Cys Glu Asn Arg Lys
                 740                 745                 750

 Arg Arg Lys Glu Lys Ser Val Gly Asp Glu Glu Asp Thr Pro Met
                 755                 760                 765

 Ile Cys Ser Ser Ile Val Ser Thr Pro Val Gly Ile Met Ala Ser
                 770                 775                 780

 Asp Tyr Asp Pro Lys Leu Gln Met Gln Glu Gly Val Arg Ser Gly
                 785                 790                 795

 Phe Ala Met Ala Gly His Glu Asn Leu Ser His Gly His Thr Glu
                 800                 805                 810

 Arg Phe Asp Pro Cys Arg Pro Gln Leu Gln Pro Gly Ser Pro Ser
                 815                 820                 825

 Leu Val Ser Glu Glu Ser Pro Ser Ala Ile Asp Ser Asp Lys Met
                 830                 835                 840

 Ser Asp Leu Gly Gly Arg Lys Pro Pro Gly Asn Val Ile Ser Val
                 845                 850                 855

 Ile Gln His Thr Asn Ser Leu Ser Arg Pro Asn Ser Phe Glu Arg
                 860                 865                 870

 Ser Glu Ser Ala Glu Leu Val Ala Cys Thr Gln Asp Lys Ala Pro
                 875                 880                 885

 Ser Pro Ser Glu Thr Cys Asp Ser Glu Ile Ser Glu Ala Pro Val
                 890                 895                 900

 Ser Pro Glu Trp Ala Pro Pro Gly Asp Gly Ala Glu Ser Gly Gly
                 905                 910                 915

 Lys Pro Ser Pro Ser Gln Gln Val Gln Gln Gln Ser Tyr His Thr
                 920                 925                 930

 Gln Pro Arg Leu Val Arg Gln His Asn Ile Gln Val Pro Glu Ile
                 935                 940                 945

 Arg Val Thr Glu Glu Pro Asp Lys Pro Glu Lys Glu Lys Glu Ala
                 950                 955                 960

 Gln Ser Lys Glu Pro Glu Lys Pro Val Glu Glu Phe Gln Trp Pro
                 965                 970                 975

 Gln Arg Ser Glu Thr Leu Ser Gln Leu Pro Ala Glu Lys Leu Pro
                 980                 985                 990

 Pro Lys Lys Lys Arg Leu Arg Leu Ala Asp Met Glu His Ser Ser
                 995                1000                1005

 Gly Glu Ser Ser Phe Glu Ser Thr Gly Thr Gly Leu Ser Arg Ser
                1010                1015                1020

 Pro Ser Gln Glu Ser Asn Leu Ser His Ser Ser Ser Phe Ser Met
                1025                1030                1035

 Ser Phe Glu Arg Glu Glu Thr Ser Lys Leu Ser Ala Leu Pro Lys
                1040                1045                1050

 Gln Asp Glu Phe Gly Lys His Ser Glu Phe Leu Thr Val Pro Ala
                1055                1060                1065

 Gly Ser Tyr Ser Leu Ser Val Pro Gly His His His Gln Lys Glu
                1070                1075                1080

 Met Arg Arg Cys Ser Ser Glu Gln Met Pro Cys Pro His Pro Ala
                1085                1090                1095

 Glu Val Pro Glu Val Arg Ser Lys Ser Phe Asp Tyr Gly Asn Leu
                1100                1105                1110

 Ser His Ala Pro Val Ser Gly Ala Ala Ala Ser Thr Val Ser Pro
                1115                1120                1125

 Ser Arg Glu Arg Lys Lys Cys Phe Leu Val Arg Gln Ala Ser Phe
                1130                1135                1140

 Ser Gly Ser Pro Glu Ile Ser Gln Gly Glu Val Gly Met Asp Gln
                1145                1150                1155

 Ser Val Lys Gln Glu Gln Leu Glu His Leu His Ala Gly Leu Arg
                1160                1165                1170

 Ser Gly Trp His His Gly Pro Pro Ala Val Leu Pro Pro Leu Gln
                1175                1180                1185

 Gln Glu Asp Pro Gly Lys Gln Val Ala Gly Pro Cys Pro Pro Leu
                1190                1195                1200

 Ser Ser Gly Pro Leu His Leu Ala Gln Pro Gln Ile Met His Met
                1205                1210                1215

 Asp Ser Gln Glu Ser Leu Arg Asn Pro Leu Ile Gln Pro Thr Ser
                1220                1225                1230

 Tyr Met Thr Ser Lys His Leu Pro Glu Gln Pro His Leu Phe Pro
                1235                1240                1245

 His Gln Glu Thr Ile Pro Phe Ser Pro Ile Gln Asn Ala Leu Phe
                1250                1255                1260

 Gln Phe Gln Tyr Pro Thr Val Cys Met Val His Leu Pro Ala Gln
                1265                1270                1275

 Gln Pro Pro Trp Trp Gln Ala His Phe Pro His Pro Phe Ala Gln
                1280                1285                1290

 His Pro Gln Lys Ser Tyr Gly Lys Pro Ser Phe Gln Thr Glu Ile
                1295                1300                1305

 His Ser Ser Tyr Pro Leu Glu His Val Ala Glu His Thr Gly Lys
                1310                1315                1320

 Lys Pro Ala Glu Tyr Ala His Thr Lys Glu Gln Thr Tyr Pro Cys
                1325                1330                1335

 Tyr Ser Gly Ala Ser Gly Leu His Pro Lys Asn Leu Leu Pro Lys
                1340                1345                1350

 Phe Pro Ser Asp Gln Ser Ser Lys Ser Thr Glu Thr Pro Ser Glu
                1355                1360                1365

 Gln Val Leu Gln Glu Asp Phe Ala Ser Ala Asn Ala Gly Ser Leu
                1370                1375                1380

 Gln Ser Leu Pro Gly Thr Val Val Pro Val Arg Ile Gln Thr His
                1385                1390                1395

 Val Pro Ser Tyr Gly Ser Val Met Tyr Thr Ser Ile Ser Gln Ile
                1400                1405                1410

 Leu Gly Gln Asn Ser Pro Ala Ile Val Ile Cys Lys Val Asp Glu
                1415                1420                1425

 Asn Met Thr Gln Arg Thr Leu Val Thr Asn Ala Ala Met Gln Gly
                1430                1435                1440

 Ile Gly Phe Asn Ile Ala Gln Val Leu Gly Gln His Ala Gly Leu
                1445                1450                1455

 Glu Lys Tyr Pro Ile Trp Lys Ala Pro Gln Thr Leu Pro Leu Gly
                1460                1465                1470

 Leu Glu Ser Ser Ile Pro Leu Cys Leu Pro Ser Thr Ser Asp Ser
                1475                1480                1485

 Val Ala Thr Leu Gly Gly Ser Lys Arg Met Leu Ser Pro Ala Ser
                1490                1495                1500

 Ser Leu Glu Leu Phe Met Glu Thr Lys Gln Gln Lys Arg Val Lys
                1505                1510                1515

 Glu Glu Lys Met Tyr Gly Gln Ile Val Glu Glu Leu Ser Ala Val
                1520                1525                1530

 Glu Leu Thr Asn Ser Asp Ile Lys Lys Asp Leu Ser Arg Pro Gln
                1535                1540                1545

 Lys Pro Gln Leu Val Arg Gln Gly Cys Ala Ser Glu Pro Lys Asp
                1550                1555                1560

 Gly Leu Gln Ser Gly Ser Ser Ser Phe Ser Ser Leu Ser Pro Ser
                1565                1570                1575

 Ser Ser Gln Asp Tyr Pro Ser Val Ser Pro Ser Ser Arg Glu Pro
                1580                1585                1590

 Phe Pro Pro Ser Lys Glu Met Leu Ser Gly Ser Arg Ala Pro Leu
                1595                1600                1605

 Pro Gly Gln Lys Ser Ser Gly Pro Ser Glu Ser Lys Glu Ser Ser
                1610                1615                1620

 Asp Glu Leu Asp Ile Asp Glu Thr Ala Ser Asp Met Ser Met Ser
                1625                1630                1635

 Pro Gln Ser Ser Ser Leu Pro Ala Gly Asp Gly Gln Leu Glu Glu
                1640                1645                1650

 Glu Gly Lys Gly His Lys Arg Pro Val Gly Met Leu Val Arg Met
                1655                1660                1665

 Ala Ser Ala Pro Ser Gly Asn Val Ala Asp Ser Thr Leu Leu Leu
                1670                1675                1680

 Thr Asp Met Ala Asp Phe Gln Gln Ile Leu Gln Phe Pro Ser Leu
                1685                1690                1695

 Arg Thr Thr Thr Thr Val Ser Trp Cys Phe Leu Asn Tyr Thr Lys
                1700                1705                1710

 Pro Asn Tyr Val Gln Gln Ala Thr Phe Lys Ser Ser Val Tyr Ala
                1715                1720                1725

 Ser Trp Cys Ile Ser Ser Cys Asn Pro Asn Pro Ser Gly Leu Asn
                1730                1735                1740

 Thr Lys Thr Thr Leu Ala Leu Leu Arg Ser Lys Gln Lys Ile Thr
                1745                1750                1755

 Ala Glu Ile Tyr Thr Leu Ala Ala Met His Arg Pro Gly Thr Gly
                1760                1765                1770

 Lys Leu Thr Ser Ser Ser Ala Trp Lys Gln Phe Thr Gln Met Lys
                1775                1780                1785

 Pro Asp Ala Ser Phe Leu Phe Gly Ser Lys Leu Glu Arg Lys Leu
                1790                1795                1800

 Val Gly Asn Ile Leu Lys Glu Arg Gly Lys Gly Asp Ile His Gly
                1805                1810                1815

 Asp Lys Asp Ile Gly Ser Lys Gln Thr Glu Pro Ile Arg Ile Lys
                1820                1825                1830

 Ile Phe Glu Gly Gly Tyr Lys Ser Asn Glu Asp Tyr Val Tyr Val
                1835                1840                1845

 Arg Gly Arg Gly Arg Gly Lys Tyr Ile Cys Glu Glu Cys Gly Ile
                1850                1855                1860

 Arg Cys Lys Lys Pro Ser Met Leu Lys Lys His Ile Arg Thr His
                1865                1870                1875

 Thr Asp Val Arg Pro Tyr Val Cys Lys Leu Cys Asn Phe Ala Phe
                1880                1885                1890

 Lys Thr Lys Gly Asn Leu Thr Lys His Met Lys Ser Lys Ala His
                1895                1900                1905

 Met Lys Lys Cys Leu Glu Leu Gly Val Ser Met Thr Ser Val Asp
                1910                1915                1920

 Asp Thr Glu Thr Glu Glu Ala Glu Asn Leu Glu Asp Leu His Lys
                1925                1930                1935

 Ala Ala Glu Lys His Ser Met Ser Ser Ile Ser Thr Asp His Gln
                1940                1945                1950

 Phe Ser Asp Ala Glu Glu Ser Asp Gly Glu Asp Gly Asp Asp Asn
                1955                1960                1965

 Asp Asp Asp Asp Glu Asp Glu Asp Asp Phe Asp Asp Gln Gly Asp
                1970                1975                1980

 Leu Thr Pro Lys Thr Arg Ser Arg Ser Thr Ser Pro Gln Pro Pro
                1985                1990                1995

 Arg Phe Ser Ser Leu
                2000

<210> 2644
<211> 9175
<212> DNA
<213> Homo sapien

<400> 2644
 tatgtttagt cccatatgct cttcctgaat cttgccactg cccatcaaga 50

 gatagaatac atttcccctc cccttgaaca tggaagcaac caagctttaa 100

 gaagcacagc tttggagaca ctccatgagt ctgcactgct ttcaggggaa 150

 ctagcactta agaccttgtg taacaaaatg gacactgggg acacagctct 200

 aggacaaaaa gctacctcaa ggtctggaga aactgataaa gcatcaggta 250

 gatggagaca ggaacaatca gctgttatta agatgagcac ttttggcagt 300

 catgaaggac agcggcaacc acaaatagag cctgagcaaa tcggaaacac 350

 agcatcagca caactgtttg gttctgggaa actggcctcc cctagtgaag 400

 tggtgcagca agtcgcagag aagcaatatc caccgcatcg tccgagtcct 450

 tactcatgcc aacactcact ctctttccct cagcactcat tgccacaggg 500

 ggtcatgcac agcaccaagc cacatcagag cctcgaaggt cctccgtggc 550

 ttttccctgg ccctttgcca tccgttgcct ctgaggactt atttcctttt 600

 cctatacatg gccacagtgg tggttatcct agaaaaaaga tttcaagtct 650

 gaaccctgct tatagccaat actcccagaa aagtattgaa caggcagaag 700

 aggctcacaa gaaagagcac aaacccaaaa agcctggcaa gtacatttgc 750

 ccttactgca gcagagcgtg tgccaaacct agtgtactga aaaaacacat 800

 caggtcccat actggggagc ggccatatcc atgtatacct tgtggtttct 850

 ctttcaagac aaagagcaat ttgtacaagc acaggaagtc acatgcccat 900

 gcaattaagg caggattagt acctttcaca gagtcagctg tatctaaatt 950

 ggacctagag gctggtttta ttgatgtaga agcagaaata cattcagatg 1000

 gtgaacagag tacagacaca gatgaggaga gttctttatt tgccgaggct 1050

 tctgacaaaa tgagtcctgg tccacccatc ccactggaca ttgccagcag 1100

 aggcggctat catgggtcat tggaagaatc attgggaggt ccaatgaagg 1150

 tgccgatttt gattatccct aaaagtggga ttcctctccc taatgaaagc 1200

 tctcagtata ttggccctga tatgctacca aatccatctt taaatactaa 1250

 ggctgatgat tcgcacacag tcaaacagaa acttgcacta agactgtcag 1300

 agaaaaaagg acaagattct gagccatcgc tcaaccttct gagcccgcac 1350

 agtaaaggaa gcactgattc tggttacttt tctcgctcag aaagtgctga 1400

 gcagcaaata agccctccca acacaaatgc aaagtcttat gaagaaatca 1450

 tctttggaaa atactgtcgg cttagtccga gaaatgcact cagtgttaca 1500

 accacaagtc aggagcgtgc cgcaatgggt aggaagggca taatggaacc 1550

 attacctcac gttaacacca ggttagatgt caagatgttt gaagatcctg 1600

 tttcacagct gatcccaagc aagggagatg tcgaccccag tcaaacgagc 1650

 atgctgaaat ccactaagtt caacagtgag tccagacaac cccagattat 1700

 tccatcatct atcaggaacg aaggaaaact ttatccagca aacttccaag 1750

 gcagcaaccc ggttctctta gaagctcctg tagactcttc accccttatt 1800

 agaagcaact cagtgccaac ttcttcagca actaatctaa ctattcctcc 1850

 ttctttgaga ggaagtcact catttgatga aaggatgact ggttccgacg 1900

 atgtattcta tccagggacc gtgggcatac cccctcagcg catgctaaga 1950

 agacaagcgg catttgagct gccttcggta caggagggcc acgtggaagt 2000

 cgagcaccat ggcaggatgt tgaagggtat cagcagttca tccctgaagg 2050

 aaaagaaatt gtctcctggg gacagggttg ggtatgacta tgatgtctgt 2100

 cggaaaccct ataagaagtg ggaggactct gaaacaccaa agcaaaacta 2150

 cagggacatt tcctgcttga gttctttaaa gcatggtgga gaatatttca 2200

 tggatcccgt ggtgccattg cagggagtac caagcatgtt tggaactacc 2250

 tgtgaaaaca ggaaacgccg gaaagagaag agcgtagggg atgaagagga 2300

 cacgcccatg atctgcagca gcattgtaag cactcctgtg ggcatcatgg 2350

 cttccgatta tgaccccaaa ctgcagatgc aggaaggagt caggagtgga 2400

 tttgccatgg ctggacacga aaacctttct catggtcaca cggaacgctt 2450

 tgacccatgt cggccccaac tgcagcctgg aagtccatct cttgtgtcag 2500

 aggagtcacc ttcagccatt gattcagaca agatgtcaga cctagggggc 2550

 aggaaacctc ctggaaatgt gatttctgtg attcagcaca ccaactcact 2600

 gagccgaccc aattcatttg aaaggtctga gtcagccgaa cttgtggctt 2650

 gcacacagga taaagcccct tccccttcag agacttgtga cagtgagatt 2700

 tcagaagccc cagtgagtcc tgagtgggct ccacctgggg atggtgcaga 2750

 aagtgggggg aaaccctctc catctcagca ggtgcagcag cagtcctatc 2800

 acacacagcc caggctagtt cggcaacaca acatccaggt tcctgagatt 2850

 cgagtgaccg aggagcctga taaacctgag aaggagaagg aagcccagag 2900

 caaagagcca gagaagcctg tggaagaatt tcagtggccc cagagaagtg 2950

 agaccctttc ccagctcccc gcggagaagt tgcctcccaa aaagaagcgt 3000

 ctgcgacttg cagatatgga gcactcctca ggggagtcca gctttgaatc 3050

 cacaggcaca ggcctctccc gcagccccag ccaagaaagc aacttgtccc 3100

 acagctccag tttctccatg tcttttgaaa gagaagaaac cagtaagctt 3150

 tctgcacttc ctaagcagga tgagtttggg aagcattcag agtttctgac 3200

 tgtccctgct ggttcatact cattgtctgt cccaggccat caccaccaga 3250

 aagagatgcg acgctgctca tcagagcaga tgccttgtcc tcacccagcg 3300

 gaagtcccag aagttcggag caaatcattt gattatggga atctgtccca 3350

 tgctcctgtg tcgggagcag cagcctccac ggtatcaccg tccagggaga 3400

 ggaagaaatg ctttctggtg cggcaagctt ccttcagtgg ctccccagaa 3450

 atctcccagg gcgaggttgg catggatcag agcgtgaagc aagagcagct 3500

 ggagcacctg catgctggcc tccggtccgg gtggcaccat ggcccgcctg 3550

 ctgtgctgcc tcctcttcag caagaggacc cagggaagca ggtggcgggt 3600

 ccttgtcccc cgctgagctc ggggccactg cacctggccc agccacagat 3650

 catgcacatg gacagtcagg aatctttgag aaatcccttg atccaaccaa 3700

 catcctatat gacaagcaag cacttacctg aacagccaca cttatttcca 3750

 catcaagaga caattccatt ttctccaatc cagaatgcct tgtttcagtt 3800

 tcagtatcct acagtttgta tggttcattt accagctcag cagcctccct 3850

 ggtggcaggc acatttccca catccctttg ctcagcaccc tcagaagagc 3900

 tatggcaagc cctcttttca gacagaaatc cattcgagct atcccttaga 3950

 gcatgtggca gagcacactg gaaagaaacc tgctgagtat gcacacacga 4000

 aagagcagac ctacccatgt tattcaggag catcagggct acacccaaag 4050

 aaccttcttc caaagtttcc atcagaccag agcagtaagt caactgaaac 4100

 gccctctgag caggttcttc aagaagattt tgcctcggca aatgctgggt 4150

 ctttgcagtc cctcccagga acagtggttc ctgttcggat ccagacgcac 4200

 gtaccatcct atggaagtgt catgtacaca agcatttctc agatacttgg 4250

 gcagaatagc cctgccattg tcatatgcaa agtcgatgag aatatgaccc 4300

 aaaggacact ggtcaccaac gcagccatgc aagggatagg attcaacatt 4350

 gcccaggtgc tggggcagca tgcgggcttg gagaagtacc ccatttggaa 4400

 agcacctcag actttgcccc tcggcttaga atcctccatc cccttgtgtt 4450

 taccttccac ctctgacagc gtggccaccc tgggaggtag caagcgaatg 4500

 ctttctccag ccagtagctt ggagctcttc atggaaacca agcagcagaa 4550

 aagggtcaaa gaagaaaaga tgtacggaca gattgtggag gagcttagtg 4600

 ctgtggagct gaccaactca gacatcaaaa aggacctctc ccgcccccag 4650

 aaaccccagc tggttcgaca aggatgtgct tctgagccaa aagatggctt 4700

 gcagtcaggg tcatcttcct tctcctcgct gtcgccctcc tcatctcaag 4750

 actatccttc tgttagcccg tcttccaggg agccattccc gcccagcaag 4800

 gagatgcttt ccggttcccg ggcaccactt ccggggcaga agtccagtgg 4850

 gccttctgaa agcaaagaat cttcagatga attagatatc gatgagacgg 4900

 catcggacat gagcatgagc ccacagagtt cttcattacc agcaggagat 4950

 ggtcagctgg aagaggaagg gaagggccac aagcggcctg ttggcatgct 5000

 ggtccgcatg gcctctgccc ccagcgggaa cgtggcagac tcaactcttc 5050

 ttctcacgga catggcagat ttccagcaga ttcttcagtt ccccagtctg 5100

 cggacaacaa ctactgtgag ttggtgcttc ttgaattata caaaacccaa 5150

 ttatgtgcaa caggccacct tcaaatcctc ggtttatgct tcatggtgca 5200

 ttagttcctg taatccaaac ccatcaggat tgaacaccaa gaccacgctg 5250

 gctcttctga ggtccaagca aaaaatcact gcagaaattt atactctggc 5300

 tgctatgcat aggcctggaa ccggcaagct tacatcatca agtgcttgga 5350

 agcagtttac tcagatgaaa cctgatgcgt cctttttatt tggcagcaaa 5400

 ctagaaagga aactagtggg aaatatctta aaggaaagag ggaaaggaga 5450

 tattcatgga gataaagata ttggatccaa acaaactgag ccaatccgaa 5500

 ttaaaatatt tgaaggaggg tacaaatcga atgaagatta tgtatatgtc 5550

 agaggacgtg gccggggaaa gtacatttgt gaagaatgtg ggattcgctg 5600

 taagaagcca agcatgctca aaaaacacat ccgtacccat actgatgttc 5650

 ggccttatgt atgcaagtta tgtaactttg ccttcaaaac gaaaggaaac 5700

 ctaacgaagc atatgaaatc taaagcacac atgaaaaaat gcctggaatt 5750

 gggagtctca atgacatcgg tggatgatac agaaactgag gaagcagaaa 5800

 atttggaaga tttgcacaaa gcagcagaga agcatagcat gtccagcatt 5850

 tcaactgatc atcagttctc cgatgctgag gaatcagatg gtgaggatgg 5900

 agatgataat gatgatgatg atgaagatga agatgacttt gacgaccagg 5950

 gagatttaac accaaaaaca agatcaagaa gcaccagtcc tcagcctcct 6000

 agattctcct ccttgcctgt gaatgttggc gccgtacccc acggggttcc 6050

 ttcagatagt tccctgggac attcttcgtt gatcagctat ttggttactt 6100

 tgccaagtat tcgagttact cagcttatga cacccagtga ttcatgtgaa 6150

 gatacccaga tgacagaata ccagaggcta ttccagagca aaagtacgga 6200

 ctcagaacca gacaaagaca gattggacat acctagttgt atggatgagg 6250

 agtgcatgct accttcagag ccaagctcct ctcccaggga cttctcaccc 6300

 tcaagccacc attcctctcc aggatatgat tcttcaccct gtcgagataa 6350

 ttcaccaaag aggtatctga tacccaaagg agatttatct cccaggagac 6400

 atttatcacc taggagagat ctgtcaccca tgagacatct ttcaccaaca 6450

 aaggaagctg cattgagaag agagatgtcc caaagagatg tttcaccaag 6500

 aaggcatttg tctccaagga ggccagtgtc tcctgggaaa gatatcacag 6550

 caagaagaga cctctcccct agaagagaga gaagatacat gaccacaata 6600

 agagcgccat ctcccagaag ggctttatac cataacccac cattgtccat 6650

 gggacagtat ttgcaagcag agccaattgt attggggcct cctaatttaa 6700

 gaagaggatt acctcaggtt ccttacttca gtctctatgg agaccaagaa 6750

 ggtgcttatg aacatccagg ctccagcctt ttccctgagg gtcctaatga 6800

 ctatgtcttc agtcatcttc cactccactc tcagcaacaa gtgcgagccc 6850

 ctatccccat ggtgcccgtt ggtgggatcc agatggttca ctccatgccg 6900

 ccagcccttt ccagtttaca tccttcaccc acattgcccc tgccaatgga 6950

 gggctttgag gagaagaaag gcgcgtcagg ggagtccttc tccaaggacc 7000

 cctatgtgct ttctaagcag catgagaagc gaggtcctca cgctttgcag 7050

 tcatctggtc cgcctagcac tccctcctct cctcggctgt tgatgaaaca 7100

 gagcacttcg gaagacagcc taaacgcaac agagcgggaa caggaggaaa 7150

 atatacagac ttgtacaaaa gccattgcct ctctccggat tgccacggaa 7200

 gaggcagctc tgctcgggcc agatcagcca gcgcgggtgc aggagcccca 7250

 ccagaacccc ctgggaagtg cacatgttag cattagacac tttagtagac 7300

 ctgagccagg tcagccctgt acctcagcca cccaccctga cttgcatgat 7350

 ggtgaaaagg acaattttgg tacatcacag actccattag ctcactccac 7400

 gttttacagc aagagttgtg tggatgacaa gcagttggac tttcacagca 7450

 gcaaggaatt atcttcaagc acagaggaaa gcaaagatcc ttcatcagaa 7500

 aagagtcagc tacattgatc tatgatgcat ggagactttc atttccacat 7550

 tttcccattt ttttgttttt gtttttctag aaatggaggt aatccagttt 7600

 atagcatgcc tgtcctaagt tacagtagtt tgctattata tatacttttg 7650

 ttatatcaaa agaattaggt aaattaacaa gtcatcatga gcctgaccaa 7700

 aacaaaattt gaaattaacc tattgggtct ggtactttta aaattgtaca 7750

 gatgtttgtg ccttttcttt actttgctta tattcttata agcatttttt 7800

 agcagtaatt tgtacatatt ttagaatttg tgtatctgct ttgtaataaa 7850

 tgtaatttct ttcctttttt ggacacttgg atctaaatga tgtaaagcaa 7900

 aacagcatca atatatatgt gaggttgcac taaaacatat ttttatatga 7950

 ttaaaactga acagctttta tgtacagctc tgattctgta atactaatat 8000

 ttatttactt tgtttcataa attgtacatt ttttcttaat gttgtggatt 8050

 gcttttctat gtgaagcatg ggatttactg ttgcgtaact agaacaaaaa 8100

 tgtacattgt aaacaagata tttaaactag agtatcttat tctgcactta 8150

 tgcattagtt aaaaaaagat aaaggatgta tcagtcagtt cttaactctt 8200

 gtatattttt ttgtctcttg tttgctggat tgactataac ttaagtgctg 8250

 attgtgattt taaaatgata gtaccgtaaa gcattaaagt aaacaatgtg 8300

 ctattgtgag ttttttcaaa gctttataaa tcagttataa ataatattaa 8350

 aagtatttgg tcttatgtga acatgttgat ctatatactc atctaaaaat 8400

 atgggaaaac attccacccc atgtaaatat gtacaagtgc atcactggta 8450

 caattttatg taactcagtt ggacactagg ttgccacaga cctatgctag 8500

 gtgtctttaa aaaattaagg tgacaaagca catgggactg tgtagagctt 8550

 ggttatcggc cggcccggtg gcttggcagg cagtctgtcg ctgctcatgg 8600

 agaagacctg ggcttagcaa tctccttagt tcttgctaca caggatggtg 8650

 actggaacta aggctacaca gagggtcgca cttggactct gagggttggg 8700

 tgtggaaggg ggaaaagggg atggagacct gctccccagc tcttcctgtc 8750

 agccggttta catgggaaca gggttaacat ctgtgttagg ggaggtcacc 8800

 ttaccctttt tcatagggga agagtgtcac actcctggct atctcagggg 8850

 gaatggggaa aagaatcttt caagggcaaa gaactcgtgg gaggatgtct 8900

 gttgtatgta atactcacaa tggcttttgg ttagtgttga aggtgggaag 8950

 agcatttgta ggtccagaag agtgaaagag agggaggggt gcagcaacat 9000

 gtgcacaggc acgcacatgt gtgcacgcac acatacaatc tgggttatct 9050

 ttgtgctata tagtggatta taattctgtg aaaccaagtt tgtatattga 9100

 attacattaa ggagtgttct ttaaaaagag aaataaatat acaattacat 9150

 gcttaaaaaa aaaaaaaaaa aaaaa 9175

<210> 2645
<211> 2500
<212> PRT
<213> Homo sapien

<400> 2645
 Met Leu Phe Leu Asn Leu Ala Thr Ala His Gln Glu Ile Glu Tyr
   1               5                  10                  15

 Ile Ser Pro Pro Leu Glu His Gly Ser Asn Gln Ala Leu Arg Ser
                  20                  25                  30

 Thr Ala Leu Glu Thr Leu His Glu Ser Ala Leu Leu Ser Gly Glu
                  35                  40                  45

 Leu Ala Leu Lys Thr Leu Cys Asn Lys Met Asp Thr Gly Asp Thr
                  50                  55                  60

 Ala Leu Gly Gln Lys Ala Thr Ser Arg Ser Gly Glu Thr Asp Lys
                  65                  70                  75

 Ala Ser Gly Arg Trp Arg Gln Glu Gln Ser Ala Val Ile Lys Met
                  80                  85                  90

 Ser Thr Phe Gly Ser His Glu Gly Gln Arg Gln Pro Gln Ile Glu
                  95                 100                 105

 Pro Glu Gln Ile Gly Asn Thr Ala Ser Ala Gln Leu Phe Gly Ser
                 110                 115                 120

 Gly Lys Leu Ala Ser Pro Ser Glu Val Val Gln Gln Val Ala Glu
                 125                 130                 135

 Lys Gln Tyr Pro Pro His Arg Pro Ser Pro Tyr Ser Cys Gln His
                 140                 145                 150

 Ser Leu Ser Phe Pro Gln His Ser Leu Pro Gln Gly Val Met His
                 155                 160                 165

 Ser Thr Lys Pro His Gln Ser Leu Glu Gly Pro Pro Trp Leu Phe
                 170                 175                 180

 Pro Gly Pro Leu Pro Ser Val Ala Ser Glu Asp Leu Phe Pro Phe
                 185                 190                 195

 Pro Ile His Gly His Ser Gly Gly Tyr Pro Arg Lys Lys Ile Ser
                 200                 205                 210

 Ser Leu Asn Pro Ala Tyr Ser Gln Tyr Ser Gln Lys Ser Ile Glu
                 215                 220                 225

 Gln Ala Glu Glu Ala His Lys Lys Glu His Lys Pro Lys Lys Pro
                 230                 235                 240

 Gly Lys Tyr Ile Cys Pro Tyr Cys Ser Arg Ala Cys Ala Lys Pro
                 245                 250                 255

 Ser Val Leu Lys Lys His Ile Arg Ser His Thr Gly Glu Arg Pro
                 260                 265                 270

 Tyr Pro Cys Ile Pro Cys Gly Phe Ser Phe Lys Thr Lys Ser Asn
                 275                 280                 285

 Leu Tyr Lys His Arg Lys Ser His Ala His Ala Ile Lys Ala Gly
                 290                 295                 300

 Leu Val Pro Phe Thr Glu Ser Ala Val Ser Lys Leu Asp Leu Glu
                 305                 310                 315

 Ala Gly Phe Ile Asp Val Glu Ala Glu Ile His Ser Asp Gly Glu
                 320                 325                 330

 Gln Ser Thr Asp Thr Asp Glu Glu Ser Ser Leu Phe Ala Glu Ala
                 335                 340                 345

 Ser Asp Lys Met Ser Pro Gly Pro Pro Ile Pro Leu Asp Ile Ala
                 350                 355                 360

 Ser Arg Gly Gly Tyr His Gly Ser Leu Glu Glu Ser Leu Gly Gly
                 365                 370                 375

 Pro Met Lys Val Pro Ile Leu Ile Ile Pro Lys Ser Gly Ile Pro
                 380                 385                 390

 Leu Pro Asn Glu Ser Ser Gln Tyr Ile Gly Pro Asp Met Leu Pro
                 395                 400                 405

 Asn Pro Ser Leu Asn Thr Lys Ala Asp Asp Ser His Thr Val Lys
                 410                 415                 420

 Gln Lys Leu Ala Leu Arg Leu Ser Glu Lys Lys Gly Gln Asp Ser
                 425                 430                 435

 Glu Pro Ser Leu Asn Leu Leu Ser Pro His Ser Lys Gly Ser Thr
                 440                 445                 450

 Asp Ser Gly Tyr Phe Ser Arg Ser Glu Ser Ala Glu Gln Gln Ile
                 455                 460                 465

 Ser Pro Pro Asn Thr Asn Ala Lys Ser Tyr Glu Glu Ile Ile Phe
                 470                 475                 480

 Gly Lys Tyr Cys Arg Leu Ser Pro Arg Asn Ala Leu Ser Val Thr
                 485                 490                 495

 Thr Thr Ser Gln Glu Arg Ala Ala Met Gly Arg Lys Gly Ile Met
                 500                 505                 510

 Glu Pro Leu Pro His Val Asn Thr Arg Leu Asp Val Lys Met Phe
                 515                 520                 525

 Glu Asp Pro Val Ser Gln Leu Ile Pro Ser Lys Gly Asp Val Asp
                 530                 535                 540

 Pro Ser Gln Thr Ser Met Leu Lys Ser Thr Lys Phe Asn Ser Glu
                 545                 550                 555

 Ser Arg Gln Pro Gln Ile Ile Pro Ser Ser Ile Arg Asn Glu Gly
                 560                 565                 570

 Lys Leu Tyr Pro Ala Asn Phe Gln Gly Ser Asn Pro Val Leu Leu
                 575                 580                 585

 Glu Ala Pro Val Asp Ser Ser Pro Leu Ile Arg Ser Asn Ser Val
                 590                 595                 600

 Pro Thr Ser Ser Ala Thr Asn Leu Thr Ile Pro Pro Ser Leu Arg
                 605                 610                 615

 Gly Ser His Ser Phe Asp Glu Arg Met Thr Gly Ser Asp Asp Val
                 620                 625                 630

 Phe Tyr Pro Gly Thr Val Gly Ile Pro Pro Gln Arg Met Leu Arg
                 635                 640                 645

 Arg Gln Ala Ala Phe Glu Leu Pro Ser Val Gln Glu Gly His Val
                 650                 655                 660

 Glu Val Glu His His Gly Arg Met Leu Lys Gly Ile Ser Ser Ser
                 665                 670                 675

 Ser Leu Lys Glu Lys Lys Leu Ser Pro Gly Asp Arg Val Gly Tyr
                 680                 685                 690

 Asp Tyr Asp Val Cys Arg Lys Pro Tyr Lys Lys Trp Glu Asp Ser
                 695                 700                 705

 Glu Thr Pro Lys Gln Asn Tyr Arg Asp Ile Ser Cys Leu Ser Ser
                 710                 715                 720

 Leu Lys His Gly Gly Glu Tyr Phe Met Asp Pro Val Val Pro Leu
                 725                 730                 735

 Gln Gly Val Pro Ser Met Phe Gly Thr Thr Cys Glu Asn Arg Lys
                 740                 745                 750

 Arg Arg Lys Glu Lys Ser Val Gly Asp Glu Glu Asp Thr Pro Met
                 755                 760                 765

 Ile Cys Ser Ser Ile Val Ser Thr Pro Val Gly Ile Met Ala Ser
                 770                 775                 780

 Asp Tyr Asp Pro Lys Leu Gln Met Gln Glu Gly Val Arg Ser Gly
                 785                 790                 795

 Phe Ala Met Ala Gly His Glu Asn Leu Ser His Gly His Thr Glu
                 800                 805                 810

 Arg Phe Asp Pro Cys Arg Pro Gln Leu Gln Pro Gly Ser Pro Ser
                 815                 820                 825

 Leu Val Ser Glu Glu Ser Pro Ser Ala Ile Asp Ser Asp Lys Met
                 830                 835                 840

 Ser Asp Leu Gly Gly Arg Lys Pro Pro Gly Asn Val Ile Ser Val
                 845                 850                 855

 Ile Gln His Thr Asn Ser Leu Ser Arg Pro Asn Ser Phe Glu Arg
                 860                 865                 870

 Ser Glu Ser Ala Glu Leu Val Ala Cys Thr Gln Asp Lys Ala Pro
                 875                 880                 885

 Ser Pro Ser Glu Thr Cys Asp Ser Glu Ile Ser Glu Ala Pro Val
                 890                 895                 900

 Ser Pro Glu Trp Ala Pro Pro Gly Asp Gly Ala Glu Ser Gly Gly
                 905                 910                 915

 Lys Pro Ser Pro Ser Gln Gln Val Gln Gln Gln Ser Tyr His Thr
                 920                 925                 930

 Gln Pro Arg Leu Val Arg Gln His Asn Ile Gln Val Pro Glu Ile
                 935                 940                 945

 Arg Val Thr Glu Glu Pro Asp Lys Pro Glu Lys Glu Lys Glu Ala
                 950                 955                 960

 Gln Ser Lys Glu Pro Glu Lys Pro Val Glu Glu Phe Gln Trp Pro
                 965                 970                 975

 Gln Arg Ser Glu Thr Leu Ser Gln Leu Pro Ala Glu Lys Leu Pro
                 980                 985                 990

 Pro Lys Lys Lys Arg Leu Arg Leu Ala Asp Met Glu His Ser Ser
                 995                1000                1005

 Gly Glu Ser Ser Phe Glu Ser Thr Gly Thr Gly Leu Ser Arg Ser
                1010                1015                1020

 Pro Ser Gln Glu Ser Asn Leu Ser His Ser Ser Ser Phe Ser Met
                1025                1030                1035

 Ser Phe Glu Arg Glu Glu Thr Ser Lys Leu Ser Ala Leu Pro Lys
                1040                1045                1050

 Gln Asp Glu Phe Gly Lys His Ser Glu Phe Leu Thr Val Pro Ala
                1055                1060                1065

 Gly Ser Tyr Ser Leu Ser Val Pro Gly His His His Gln Lys Glu
                1070                1075                1080

 Met Arg Arg Cys Ser Ser Glu Gln Met Pro Cys Pro His Pro Ala
                1085                1090                1095

 Glu Val Pro Glu Val Arg Ser Lys Ser Phe Asp Tyr Gly Asn Leu
                1100                1105                1110

 Ser His Ala Pro Val Ser Gly Ala Ala Ala Ser Thr Val Ser Pro
                1115                1120                1125

 Ser Arg Glu Arg Lys Lys Cys Phe Leu Val Arg Gln Ala Ser Phe
                1130                1135                1140

 Ser Gly Ser Pro Glu Ile Ser Gln Gly Glu Val Gly Met Asp Gln
                1145                1150                1155

 Ser Val Lys Gln Glu Gln Leu Glu His Leu His Ala Gly Leu Arg
                1160                1165                1170

 Ser Gly Trp His His Gly Pro Pro Ala Val Leu Pro Pro Leu Gln
                1175                1180                1185

 Gln Glu Asp Pro Gly Lys Gln Val Ala Gly Pro Cys Pro Pro Leu
                1190                1195                1200

 Ser Ser Gly Pro Leu His Leu Ala Gln Pro Gln Ile Met His Met
                1205                1210                1215

 Asp Ser Gln Glu Ser Leu Arg Asn Pro Leu Ile Gln Pro Thr Ser
                1220                1225                1230

 Tyr Met Thr Ser Lys His Leu Pro Glu Gln Pro His Leu Phe Pro
                1235                1240                1245

 His Gln Glu Thr Ile Pro Phe Ser Pro Ile Gln Asn Ala Leu Phe
                1250                1255                1260

 Gln Phe Gln Tyr Pro Thr Val Cys Met Val His Leu Pro Ala Gln
                1265                1270                1275

 Gln Pro Pro Trp Trp Gln Ala His Phe Pro His Pro Phe Ala Gln
                1280                1285                1290

 His Pro Gln Lys Ser Tyr Gly Lys Pro Ser Phe Gln Thr Glu Ile
                1295                1300                1305

 His Ser Ser Tyr Pro Leu Glu His Val Ala Glu His Thr Gly Lys
                1310                1315                1320

 Lys Pro Ala Glu Tyr Ala His Thr Lys Glu Gln Thr Tyr Pro Cys
                1325                1330                1335

 Tyr Ser Gly Ala Ser Gly Leu His Pro Lys Asn Leu Leu Pro Lys
                1340                1345                1350

 Phe Pro Ser Asp Gln Ser Ser Lys Ser Thr Glu Thr Pro Ser Glu
                1355                1360                1365

 Gln Val Leu Gln Glu Asp Phe Ala Ser Ala Asn Ala Gly Ser Leu
                1370                1375                1380

 Gln Ser Leu Pro Gly Thr Val Val Pro Val Arg Ile Gln Thr His
                1385                1390                1395

 Val Pro Ser Tyr Gly Ser Val Met Tyr Thr Ser Ile Ser Gln Ile
                1400                1405                1410

 Leu Gly Gln Asn Ser Pro Ala Ile Val Ile Cys Lys Val Asp Glu
                1415                1420                1425

 Asn Met Thr Gln Arg Thr Leu Val Thr Asn Ala Ala Met Gln Gly
                1430                1435                1440

 Ile Gly Phe Asn Ile Ala Gln Val Leu Gly Gln His Ala Gly Leu
                1445                1450                1455

 Glu Lys Tyr Pro Ile Trp Lys Ala Pro Gln Thr Leu Pro Leu Gly
                1460                1465                1470

 Leu Glu Ser Ser Ile Pro Leu Cys Leu Pro Ser Thr Ser Asp Ser
                1475                1480                1485

 Val Ala Thr Leu Gly Gly Ser Lys Arg Met Leu Ser Pro Ala Ser
                1490                1495                1500

 Ser Leu Glu Leu Phe Met Glu Thr Lys Gln Gln Lys Arg Val Lys
                1505                1510                1515

 Glu Glu Lys Met Tyr Gly Gln Ile Val Glu Glu Leu Ser Ala Val
                1520                1525                1530

 Glu Leu Thr Asn Ser Asp Ile Lys Lys Asp Leu Ser Arg Pro Gln
                1535                1540                1545

 Lys Pro Gln Leu Val Arg Gln Gly Cys Ala Ser Glu Pro Lys Asp
                1550                1555                1560

 Gly Leu Gln Ser Gly Ser Ser Ser Phe Ser Ser Leu Ser Pro Ser
                1565                1570                1575

 Ser Ser Gln Asp Tyr Pro Ser Val Ser Pro Ser Ser Arg Glu Pro
                1580                1585                1590

 Phe Pro Pro Ser Lys Glu Met Leu Ser Gly Ser Arg Ala Pro Leu
                1595                1600                1605

 Pro Gly Gln Lys Ser Ser Gly Pro Ser Glu Ser Lys Glu Ser Ser
                1610                1615                1620

 Asp Glu Leu Asp Ile Asp Glu Thr Ala Ser Asp Met Ser Met Ser
                1625                1630                1635

 Pro Gln Ser Ser Ser Leu Pro Ala Gly Asp Gly Gln Leu Glu Glu
                1640                1645                1650

 Glu Gly Lys Gly His Lys Arg Pro Val Gly Met Leu Val Arg Met
                1655                1660                1665

 Ala Ser Ala Pro Ser Gly Asn Val Ala Asp Ser Thr Leu Leu Leu
                1670                1675                1680

 Thr Asp Met Ala Asp Phe Gln Gln Ile Leu Gln Phe Pro Ser Leu
                1685                1690                1695

 Arg Thr Thr Thr Thr Val Ser Trp Cys Phe Leu Asn Tyr Thr Lys
                1700                1705                1710

 Pro Asn Tyr Val Gln Gln Ala Thr Phe Lys Ser Ser Val Tyr Ala
                1715                1720                1725

 Ser Trp Cys Ile Ser Ser Cys Asn Pro Asn Pro Ser Gly Leu Asn
                1730                1735                1740

 Thr Lys Thr Thr Leu Ala Leu Leu Arg Ser Lys Gln Lys Ile Thr
                1745                1750                1755

 Ala Glu Ile Tyr Thr Leu Ala Ala Met His Arg Pro Gly Thr Gly
                1760                1765                1770

 Lys Leu Thr Ser Ser Ser Ala Trp Lys Gln Phe Thr Gln Met Lys
                1775                1780                1785

 Pro Asp Ala Ser Phe Leu Phe Gly Ser Lys Leu Glu Arg Lys Leu
                1790                1795                1800

 Val Gly Asn Ile Leu Lys Glu Arg Gly Lys Gly Asp Ile His Gly
                1805                1810                1815

 Asp Lys Asp Ile Gly Ser Lys Gln Thr Glu Pro Ile Arg Ile Lys
                1820                1825                1830

 Ile Phe Glu Gly Gly Tyr Lys Ser Asn Glu Asp Tyr Val Tyr Val
                1835                1840                1845

 Arg Gly Arg Gly Arg Gly Lys Tyr Ile Cys Glu Glu Cys Gly Ile
                1850                1855                1860

 Arg Cys Lys Lys Pro Ser Met Leu Lys Lys His Ile Arg Thr His
                1865                1870                1875

 Thr Asp Val Arg Pro Tyr Val Cys Lys Leu Cys Asn Phe Ala Phe
                1880                1885                1890

 Lys Thr Lys Gly Asn Leu Thr Lys His Met Lys Ser Lys Ala His
                1895                1900                1905

 Met Lys Lys Cys Leu Glu Leu Gly Val Ser Met Thr Ser Val Asp
                1910                1915                1920

 Asp Thr Glu Thr Glu Glu Ala Glu Asn Leu Glu Asp Leu His Lys
                1925                1930                1935

 Ala Ala Glu Lys His Ser Met Ser Ser Ile Ser Thr Asp His Gln
                1940                1945                1950

 Phe Ser Asp Ala Glu Glu Ser Asp Gly Glu Asp Gly Asp Asp Asn
                1955                1960                1965

 Asp Asp Asp Asp Glu Asp Glu Asp Asp Phe Asp Asp Gln Gly Asp
                1970                1975                1980

 Leu Thr Pro Lys Thr Arg Ser Arg Ser Thr Ser Pro Gln Pro Pro
                1985                1990                1995

 Arg Phe Ser Ser Leu Pro Val Asn Val Gly Ala Val Pro His Gly
                2000                2005                2010

 Val Pro Ser Asp Ser Ser Leu Gly His Ser Ser Leu Ile Ser Tyr
                2015                2020                2025

 Leu Val Thr Leu Pro Ser Ile Arg Val Thr Gln Leu Met Thr Pro
                2030                2035                2040

 Ser Asp Ser Cys Glu Asp Thr Gln Met Thr Glu Tyr Gln Arg Leu
                2045                2050                2055

 Phe Gln Ser Lys Ser Thr Asp Ser Glu Pro Asp Lys Asp Arg Leu
                2060                2065                2070

 Asp Ile Pro Ser Cys Met Asp Glu Glu Cys Met Leu Pro Ser Glu
                2075                2080                2085

 Pro Ser Ser Ser Pro Arg Asp Phe Ser Pro Ser Ser His His Ser
                2090                2095                2100

 Ser Pro Gly Tyr Asp Ser Ser Pro Cys Arg Asp Asn Ser Pro Lys
                2105                2110                2115

 Arg Tyr Leu Ile Pro Lys Gly Asp Leu Ser Pro Arg Arg His Leu
                2120                2125                2130

 Ser Pro Arg Arg Asp Leu Ser Pro Met Arg His Leu Ser Pro Thr
                2135                2140                2145

 Lys Glu Ala Ala Leu Arg Arg Glu Met Ser Gln Arg Asp Val Ser
                2150                2155                2160

 Pro Arg Arg His Leu Ser Pro Arg Arg Pro Val Ser Pro Gly Lys
                2165                2170                2175

 Asp Ile Thr Ala Arg Arg Asp Leu Ser Pro Arg Arg Glu Arg Arg
                2180                2185                2190

 Tyr Met Thr Thr Ile Arg Ala Pro Ser Pro Arg Arg Ala Leu Tyr
                2195                2200                2205

 His Asn Pro Pro Leu Ser Met Gly Gln Tyr Leu Gln Ala Glu Pro
                2210                2215                2220

 Ile Val Leu Gly Pro Pro Asn Leu Arg Arg Gly Leu Pro Gln Val
                2225                2230                2235

 Pro Tyr Phe Ser Leu Tyr Gly Asp Gln Glu Gly Ala Tyr Glu His
                2240                2245                2250

 Pro Gly Ser Ser Leu Phe Pro Glu Gly Pro Asn Asp Tyr Val Phe
                2255                2260                2265

 Ser His Leu Pro Leu His Ser Gln Gln Gln Val Arg Ala Pro Ile
                2270                2275                2280

 Pro Met Val Pro Val Gly Gly Ile Gln Met Val His Ser Met Pro
                2285                2290                2295

 Pro Ala Leu Ser Ser Leu His Pro Ser Pro Thr Leu Pro Leu Pro
                2300                2305                2310

 Met Glu Gly Phe Glu Glu Lys Lys Gly Ala Ser Gly Glu Ser Phe
                2315                2320                2325

 Ser Lys Asp Pro Tyr Val Leu Ser Lys Gln His Glu Lys Arg Gly
                2330                2335                2340

 Pro His Ala Leu Gln Ser Ser Gly Pro Pro Ser Thr Pro Ser Ser
                2345                2350                2355

 Pro Arg Leu Leu Met Lys Gln Ser Thr Ser Glu Asp Ser Leu Asn
                2360                2365                2370

 Ala Thr Glu Arg Glu Gln Glu Glu Asn Ile Gln Thr Cys Thr Lys
                2375                2380                2385

 Ala Ile Ala Ser Leu Arg Ile Ala Thr Glu Glu Ala Ala Leu Leu
                2390                2395                2400

 Gly Pro Asp Gln Pro Ala Arg Val Gln Glu Pro His Gln Asn Pro
                2405                2410                2415

 Leu Gly Ser Ala His Val Ser Ile Arg His Phe Ser Arg Pro Glu
                2420                2425                2430

 Pro Gly Gln Pro Cys Thr Ser Ala Thr His Pro Asp Leu His Asp
                2435                2440                2445

 Gly Glu Lys Asp Asn Phe Gly Thr Ser Gln Thr Pro Leu Ala His
                2450                2455                2460

 Ser Thr Phe Tyr Ser Lys Ser Cys Val Asp Asp Lys Gln Leu Asp
                2465                2470                2475

 Phe His Ser Ser Lys Glu Leu Ser Ser Ser Thr Glu Glu Ser Lys
                2480                2485                2490

 Asp Pro Ser Ser Glu Lys Ser Gln Leu His
                2495                2500

<210> 2646
<211> 1865
<212> DNA
<213> Homo sapien

<400> 2646
 gagtgcgcac gcatcctgcc cgcggcgcgc gcgcaggtcg gtgcgtctgt 50

 cgggggcgcg ctcgggtacc tgtaccccac gtagtcgccg gttaccgatc 100

 ggactaagtt ccagtggtga tttacaagtc aagttaaaat gtccccagaa 150

 gtggccttga accgaatatc tccaatgctc tcccctttca tatctagcgt 200

 ggtccggaat ggaaaagtgg gactggatgc tacaaactgt ttgaggataa 250

 ctgacttaaa atctggctgc acatcattga ctcctgggcc caactgtgac 300

 cgatttaaac tgcacatacc atatgctgga gagacattaa agtgggatat 350

 cattttcaat gcccaatacc cagaactgcc tcccgatttt atctttggag 400

 aagatgctga attcctgcca gacccctcag ctttgcagaa tcttgcctcc 450

 tggaatcctt caaatcctga atgtctctta cttgtggtga aggaacttgt 500

 gcaacaatat caccaattcc aatgtagccg cctccgggag agctcccgcc 550

 tcatgtttga ataccagaca ttactggagg agccacagta tggagagaac 600

 atggaaattt atgctgggaa aaaaaacaac tggactggtg aattttcagc 650

 tcgtttcctt ttgaagctgc ccgtagattt cagcaatatc cccacatacc 700

 ttctcaagga tgtaaatgaa gaccctggag aagatgtggc cctcctctct 750

 gttagttttg aggacactga agccacccag gtgtacccca agctgtactt 800

 gtcacctcga attgagcatg cacttggagg ctcctcagct cttcatatcc 850

 cagcttttcc aggaggagga tgtctcattg attacgttcc tcaagtatgc 900

 cacctgctca ccaacaaggt gcagtacgtg attcaagggt atcacaaaag 950

 aagagagtat attgctgctt ttctcagtca ctttggcaca ggtgtcgtgg 1000

 aatatgatgc agaaggcttt acaaaactca ctctgctgct gatgtggaaa 1050

 gatttttgtt ttcttgtaca cattgacctg cctctgtttt tccctcgaga 1100

 ccagccaact ctcacatttc agtccgttta tcactttacc aacagtggac 1150

 agctttactc ccaggcccaa aaaaattatc cgtacagccc cagatgggat 1200

 ggaaatgaaa tggccaaaag agcaaaggga tgccagggga gcagagatgc 1250

 ctgcagcccg tgggagcaag tcctggcctt tgcagttgca aaaactggct 1300

 gcaagctgct ccagccccag aggaactggc caagctccag agggcctcct 1350

 tggagggcct cagagggaga gagaactgct cagtaatttt gatcactttg 1400

 ggcttatttc aaaacctttg tccctcagtt ccaggaggca gcatttgcca 1450

 atggaaagct ctaggaaaca ccagtcttga gaggtggcca gccagactgc 1500

 ctgtccacat gcgtgtcagc acatacagcc gcttcctgga agccgcctgg 1550

 aatgtcttca cggcagcgtt ttgctcacac agcagctttt gcacgcccca 1600

 ggcagccccg actgctgaaa tccaacttga gctggctggt ggtccctgga 1650

 tcctagagcc cttcacttcg ggttactccc tctttcttgc ctctatttct 1700

 tagttggaag aaataaactc acaaattatg gtgcagtaat tttccgggga 1750

 aagtaaagcc tcaggaatgc ccacgccttt cttccaaagc ctttgtctct 1800

 gagacctctt aagttctaag attaaatgcc cctcgctgtt tctcctctga 1850

 aaaaaaaaaa aaaaa 1865

<210> 2647
<211> 415
<212> PRT
<213> Homo sapien

<400> 2647
 Met Ser Pro Glu Val Ala Leu Asn Arg Ile Ser Pro Met Leu Ser
   1               5                  10                  15

 Pro Phe Ile Ser Ser Val Val Arg Asn Gly Lys Val Gly Leu Asp
                  20                  25                  30

 Ala Thr Asn Cys Leu Arg Ile Thr Asp Leu Lys Ser Gly Cys Thr
                  35                  40                  45

 Ser Leu Thr Pro Gly Pro Asn Cys Asp Arg Phe Lys Leu His Ile
                  50                  55                  60

 Pro Tyr Ala Gly Glu Thr Leu Lys Trp Asp Ile Ile Phe Asn Ala
                  65                  70                  75

 Gln Tyr Pro Glu Leu Pro Pro Asp Phe Ile Phe Gly Glu Asp Ala
                  80                  85                  90

 Glu Phe Leu Pro Asp Pro Ser Ala Leu Gln Asn Leu Ala Ser Trp
                  95                 100                 105

 Asn Pro Ser Asn Pro Glu Cys Leu Leu Leu Val Val Lys Glu Leu
                 110                 115                 120

 Val Gln Gln Tyr His Gln Phe Gln Cys Ser Arg Leu Arg Glu Ser
                 125                 130                 135

 Ser Arg Leu Met Phe Glu Tyr Gln Thr Leu Leu Glu Glu Pro Gln
                 140                 145                 150

 Tyr Gly Glu Asn Met Glu Ile Tyr Ala Gly Lys Lys Asn Asn Trp
                 155                 160                 165

 Thr Gly Glu Phe Ser Ala Arg Phe Leu Leu Lys Leu Pro Val Asp
                 170                 175                 180

 Phe Ser Asn Ile Pro Thr Tyr Leu Leu Lys Asp Val Asn Glu Asp
                 185                 190                 195

 Pro Gly Glu Asp Val Ala Leu Leu Ser Val Ser Phe Glu Asp Thr
                 200                 205                 210

 Glu Ala Thr Gln Val Tyr Pro Lys Leu Tyr Leu Ser Pro Arg Ile
                 215                 220                 225

 Glu His Ala Leu Gly Gly Ser Ser Ala Leu His Ile Pro Ala Phe
                 230                 235                 240

 Pro Gly Gly Gly Cys Leu Ile Asp Tyr Val Pro Gln Val Cys His
                 245                 250                 255

 Leu Leu Thr Asn Lys Val Gln Tyr Val Ile Gln Gly Tyr His Lys
                 260                 265                 270

 Arg Arg Glu Tyr Ile Ala Ala Phe Leu Ser His Phe Gly Thr Gly
                 275                 280                 285

 Val Val Glu Tyr Asp Ala Glu Gly Phe Thr Lys Leu Thr Leu Leu
                 290                 295                 300

 Leu Met Trp Lys Asp Phe Cys Phe Leu Val His Ile Asp Leu Pro
                 305                 310                 315

 Leu Phe Phe Pro Arg Asp Gln Pro Thr Leu Thr Phe Gln Ser Val
                 320                 325                 330

 Tyr His Phe Thr Asn Ser Gly Gln Leu Tyr Ser Gln Ala Gln Lys
                 335                 340                 345

 Asn Tyr Pro Tyr Ser Pro Arg Trp Asp Gly Asn Glu Met Ala Lys
                 350                 355                 360

 Arg Ala Lys Gly Cys Gln Gly Ser Arg Asp Ala Cys Ser Pro Trp
                 365                 370                 375

 Glu Gln Val Leu Ala Phe Ala Val Ala Lys Thr Gly Cys Lys Leu
                 380                 385                 390

 Leu Gln Pro Gln Arg Asn Trp Pro Ser Ser Arg Gly Pro Pro Trp
                 395                 400                 405

 Arg Ala Ser Glu Gly Glu Arg Thr Ala Gln
                 410                 415

<210> 2648
<211> 1802
<212> DNA
<213> Homo sapien

<400> 2648
 gggcagctcc accctgggag ggactgtggc ccaggtactg cccgggtgct 50

 actttatggg cagcagctca gttgagttag agtctggaag acctcagaag 100

 acctcctgtc ctatgaggcc ctccccatgg ctttagagac gatctgccga 150

 ccctctggga gaaaatccag caagatgcaa gccttcagaa tctgggatgt 200

 taaccagaag accttctatc tgaggaacaa ccaactagtt gctggatact 250

 tgcaaggacc aaatgtcaat ttagaagaaa agatagatgt ggtacccatt 300

 gagcctcatg ctctgttctt gggaatccat ggagggaaga tgtgcctgtc 350

 ctgtgtcaag tctggtgatg agaccagact ccagctggag gcagttaaca 400

 tcactgacct gagcgagaac agaaagcagg acaagcgctt cgccttcatc 450

 cgctcagaca gcggccccac caccagtttt gagtctgccg cctgccccgg 500

 ttggttcctc tgcacagcga tggaagctga ccagcccgtc agcctcacca 550

 atatgcctga cgaaggcgtc atggtcacca aattctactt ccaggaggac 600

 gagtagtact gcccaggcct gcctgttccc attcttgcat ggcaaggact 650

 gcagggactg ccagtccccc tgccccaggg ctcccggcta tgggggcact 700

 gaggaccagc cattgagggg tggaccctca gaaggcgtca caagaacctg 750

 gtcacaggac tctgcctcct cttcaactga ccagcctcca tgctgcctcc 800

 agaatggtct ttctaatgtg tgaatcagag cacagcagcc cctgcacaaa 850

 gcccttccat gtcgcctctg cattcaggat caaaccccga ccacctgccc 900

 aacctgctct cctcttgcca ctgcctcttc ctccctcatt ccaccttccc 950

 atgccctgga tccatcaggc cacttgatga cccccaacca agtggctccc 1000

 acaccctgtt ttacaaaaaa gaaaagacca gtccatgagg gaggttttta 1050

 agggtttgtg gaaaatgaaa attaggattt catgattttt ttttttcagt 1100

 ccccgtgaag gagagccctt catttggaga ttatgttctt tcggggagag 1150

 gctgaggact taaaatattc ctgcatttgt gaaatgatgg tgaaagtaag 1200

 tggtagcttt tcccttcttt ttcttctttt tttgtgatgt cccaacttgt 1250

 aaaaattaaa agttatggta ctatgttagc cccataattt tttttttcct 1300

 tttaaaacac ttccataatc tggactcctc tgtccaggca ctgctgccca 1350

 gcctccaagc tccatctcca ctccagattt tttacagctg cctgcagtac 1400

 tttacctcct atcagaagtt tctcagctcc caaggctctg agcaaatgtg 1450

 gctcctgggg gttctttctt cctctgctga aggaataaat tgctccttga 1500

 cattgtagag cttctggcac ttggagactt gtatgaaaga tggctgtgcc 1550

 tctgcctgtc tcccccaccg ggctgggagc tctgcagagc aggaaacatg 1600

 actcgtatat gtctcaggtc cctgcagggc caagcaccta gcctcgctct 1650

 tggcaggtac tcagcgaatg aatgctgtat atgttgggtg caaagttccc 1700

 tacttcctgt gacttcagct ctgttttaca ataaaatctt gaaaatgcct 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aa 1802

<210> 2649
<211> 159
<212> PRT
<213> Homo sapien

<400> 2649
 Met Ala Leu Glu Thr Ile Cys Arg Pro Ser Gly Arg Lys Ser Ser
   1               5                  10                  15

 Lys Met Gln Ala Phe Arg Ile Trp Asp Val Asn Gln Lys Thr Phe
                  20                  25                  30

 Tyr Leu Arg Asn Asn Gln Leu Val Ala Gly Tyr Leu Gln Gly Pro
                  35                  40                  45

 Asn Val Asn Leu Glu Glu Lys Ile Asp Val Val Pro Ile Glu Pro
                  50                  55                  60

 His Ala Leu Phe Leu Gly Ile His Gly Gly Lys Met Cys Leu Ser
                  65                  70                  75

 Cys Val Lys Ser Gly Asp Glu Thr Arg Leu Gln Leu Glu Ala Val
                  80                  85                  90

 Asn Ile Thr Asp Leu Ser Glu Asn Arg Lys Gln Asp Lys Arg Phe
                  95                 100                 105

 Ala Phe Ile Arg Ser Asp Ser Gly Pro Thr Thr Ser Phe Glu Ser
                 110                 115                 120

 Ala Ala Cys Pro Gly Trp Phe Leu Cys Thr Ala Met Glu Ala Asp
                 125                 130                 135

 Gln Pro Val Ser Leu Thr Asn Met Pro Asp Glu Gly Val Met Val
                 140                 145                 150

 Thr Lys Phe Tyr Phe Gln Glu Asp Glu
                 155

<210> 2650
<211> 6466
<212> DNA
<213> Homo sapien

<400> 2650
 ctctcttgct cgctcgctcc ctctctctcc tgctggctgc ctgttctagg 50

 aagccagcgc ggagaggggg gggatgcaca gcacagggga gagagattgc 100

 gcatgttggt cagtcgtgtt ttaaagagta cagtgcgggg aggctgagag 150

 gggcgcatgc aacaacaact tttggaagga tggaagagaa gaggcgaaaa 200

 tactccatca gcagtgacaa ctctgacacc actgacagtc atgcgacatc 250

 tacatccgca tcaagatgct ccaaactgcc cagcagcacc aagtcgggct 300

 ggccccgaca gaacgaaaag aagccctccg aggttttccg gacagacttg 350

 atcacagcca tgaagatccc ggactcatac cagctcagcc cggatgacta 400

 ctacatcctg gcagacccat ggcgacagga atgggagaaa ggtgtgcagg 450

 tgcctgccgg ggcagaggcc atcccagagc ccgtggtgag gatcctccca 500

 ccactggaag gcccccctgc ccaggcatcc ccgagcagca ccatgcttgg 550

 tgagggctcc cagcctgatt ggccaggggg cagccgctat gacttggacg 600

 agattgatgc ctactggctg gagctcatca actcggagct taaggagatg 650

 gagaggccgg agctggacga gctgacatta gagcgtgtgc tggaggagct 700

 ggagaccctg tgccaccaga atatggccag ggccattgag acgcaggagg 750

 ggctgggcat cgagtacgac gaggatgttg tctgcgacgt gtgtcgctct 800

 cctgagggcg aggatggcaa cgagatggtc ttctgtgaca agtgcaacgt 850

 ctgtgtgcat caggcatgct acgggatcct caaggtgccc acgggcagct 900

 ggctgtgccg gacgtgtgcc ctgggtgtcc agccaaagtg cctgctctgc 950

 cccaagcgag gaggagcctt gaagcccact agaagtggga ccaagtgggt 1000

 gcatgtcagc tgtgccctat ggattcctga ggtcagcatc ggctgcccag 1050

 agaagatgga gcccatcacc aagatctcgc atatcccagc cagccgctgg 1100

 gctctgtcct gcagcctctg caaggaatgc acaggcacct gcatccagtg 1150

 ttccatgcct tcctgcgtca tagcgttcca tgtcacatgc gcctttgacc 1200

 acggcctgga aatgcggact atattagcag acaacgatga ggtcaagttc 1250

 aagtcattct gccaggagca cagtgacggg ggcccacgta atgagcccac 1300

 atctgagccc acggaaccca gccaggctgg cgaggacctg gaaaaggtga 1350

 ccctgcgcaa gcagcggctg cagcagctag aggaggactt ctacgagctg 1400

 gtggagccgg ctgaggtggc tgagcggctg gacctggctg aggcactggt 1450

 cgacttcatc taccagtact ggaagctgaa gaggaaagcc aatgccaacc 1500

 agccgctgct gacccccaag accgacgagg tggacaacct ggcccagcag 1550

 gagcaggacg tcctctaccg ccgcctgaag ctcttcaccc atctgcggca 1600

 ggacctagag agggttagaa atctgtgcta catggtgaca aggcgcgaga 1650

 gaacgaaaca cgccatctgc aaactccagg agcagatatt ccacctgcag 1700

 atgaaactta ttgaacagga tctgtgtcga ggcctgtcca cctcattccc 1750

 catcgatggc accttcttca acagctggct ggcacagtcg gtgcagatca 1800

 cagcagagaa catggccatg agcgagtggc cactgaacaa tgggcaccgc 1850

 gaggaccctg ctccagggct gctgtcagag gaactgctgc aggacgagga 1900

 gacactgctc agcttcatgc gggacccctc gctgcgacct ggtgaccctg 1950

 ctaggaaggc ccgaggccgc acccgcctgc ctgccaagaa gaaaccacca 2000

 ccaccaccac cgcaggacgg gcctggttca cggacgactc cagacaaagc 2050

 ccccaagaag acctggggcc aggatgcagg cagtggcaag gggggtcaag 2100

 ggccacctac caggaagcca ccacgtcgga catcttctca cttgccgtcc 2150

 agccctgcag ccggggactg tcccatccta gccacccctg aaagcccccc 2200

 gccactggcc cctgagaccc cggacgaggc agcctcagta gctgctgact 2250

 cagatgtcca agtgcctggc cctgcagcaa gccctaagcc tttgggccgg 2300

 ctccggccac cccgcgagag caaggtaacc cggagattgc cgggtgccag 2350

 gcctgatgct gggatgggac caccttcagc tgtggctgag aggcccaagg 2400

 tcagcctgca ttttgacact gagactgatg gctacttctc tgatggggag 2450

 atgagcgact cagatgtaga ggccgaggac ggtggggtgc agcggggtcc 2500

 ccgggaggca ggggcagagg aggtggtccg catgggcgta ctggcctcct 2550

 aactcacccc cttccctgtc ccaggccctg ccctggtccc cccacaaggc 2600

 ctcagcccag tcacaactgc catttccagt ctctgctgag tgtcccagac 2650

 cctcgaggct gccactccgt cgtggtttta tttttaatat agagagagtt 2700

 ttgaattcta cactgttgtc tttcctctgt gctggcctag gacattagga 2750

 ttccttccac ggctccggcc gctaggaccc tgccaggtcc cgcgcaccat 2800

 ccctgccctg cccacgtggt attgctgggc tcctggctag atgcaagcaa 2850

 ggtggacaag agctcaggac tccagcccac tgccactggg tgacacagac 2900

 tgtcgtttgg gcattatttc atggcagatg ggccagtcca gggcctaccc 2950

 cgccttgccc ccagatccca ctggggtcca tttggggggt cctgctacac 3000

 tccaccgatc cccaaggaag tataataaac gatacccagc cagagtctac 3050

 tcactgtcac aagcacaacg agtttatatg agaaagcact gagggggtgc 3100

 agagggcccg ctagttccag gggaactgaa agctgttcct gatcagcccg 3150

 tatcatctga ggcctgcctg cccaccctgc caccctcccc tcccttgctg 3200

 ctctgcccct gccagtgccc agcccagcgg ctctgggaag gggttcccag 3250

 aatccctcct gagctgtgcc atttactcag gggactccca aacagccagc 3300

 tgccagtgca ggtggagggc tgtaggggag ggccagtgcc cagacagggt 3350

 catggggctc agaccagccc actgtagaga atcactctga ggctccaact 3400

 tccttccttc cttcggggcc agtctcggcc gaagtctggt cacgctcaga 3450

 cagagctgac cagaccagac cgtttgcctt ttcaagtttc ctagtcctgc 3500

 tacaagatga gcttcttccg tggtttcctt ttggaaactc ctccttccaa 3550

 caagcagtgg gatcccgggg cccagggcgg gccggtgttg gccgctgggg 3600

 ctgttgtaag tcttgctgga tgttcccctg ttcctgagcc ttaacccctc 3650

 gcacagccat cccccccccc cgtcctgcca tccccccccg ccgtcctgcc 3700

 ttccccaccc cacccttagg tcccaggtag ttgctctgaa gagtttcagt 3750

 agagtggccc cagggtgata gctcagggaa caacaaaaaa ggaattccgt 3800

 gaaaacattt ttttttcttt gatgaattac tcctgggtca cttccaccac 3850

 tggtaaagcc agaacttctc caaaaagaac cttgcaaaaa gtccagtgaa 3900

 tcagtcgaat cattctgtgg atgccaaaga atattttgac cataatacag 3950

 cacagcctgg acctgacaac ttgtcatttg gacttttttt taaatggagt 4000

 tctttagcaa caaagtatag aaacatgttc attgcacaca cccaaggaga 4050

 agagctcaag cgcttggaag aggatgcttt gctgctgctg aagtgtacct 4100

 gggtgttaga tttcagatcc tgggctgagc ccactgtgag ctttcctaaa 4150

 ctgtgagact cacagagggg aaagatactg acggtgaaac cagcatggaa 4200

 aacgtcttta ccatgtggtt ccctcctccc caaatacata aagcaaataa 4250

 gcaggatggg gaacagcttg accttcatcc acccctaact ccaaaactat 4300

 caaggtacga cagtggcatt gtcatcgaca ctcaatttca tgtgaatttt 4350

 agcaaaacag gaaacaaaga taatgactca gttcagagga tcggacaaat 4400

 gtgtctagtc cgggtggact cggagggagt ggggtgggct tcaaggattc 4450

 tgggcgttgg gatggcatga gctaccctgt agagtttagt ctgcctgccc 4500

 gccttggtag tagtgaccag tcagtgtcag catcagtgtc ccaaccccag 4550

 tctctgttta ctgcctttga acagaacttc ttccttcccc atgctttggg 4600

 tcacctcggg ctgcaaccct gtctgtgcca gattgcccgg tctgaccctg 4650

 caggaagcaa agaggtgagc ttaaagaaca accaaactct gccaggggtc 4700

 ccagaaagcc cagggtccag cagtctcagc acttggcccc ttgccccttc 4750

 acaccatcct ggggcagggg ctgggcctcc ctggtggcag gggtgggtgg 4800

 agaattaggg agagggtgca acgagtctgg ccccttgcct cgggctggct 4850

 ggtgttcttc caagagcctc tgctcacatt gttggcctct ggattctggc 4900

 ccttcttcat tggctgttgc tttggactgg actgttgctg agcctgtgtc 4950

 ctgcagaacc cagatgtctg ttaggctggc tggctgctgc gaggggaggg 5000

 gggtggcctt tcatttgggg tgccctttca ctcccaggcc aagccctgga 5050

 gcaatcttct tcaggcagct gtctccacct ccaggatgtc cagcaggctg 5100

 caaggagaag gatgccagcc acccatcctc ccccagttcc cagcctttcc 5150

 cctgttggtc acagccgctt ctgtcttttt ccggtctact gtccccagtg 5200

 tagagggctt tgctgtccct gagactgagg caggttcctt ttccaggtca 5250

 gaggtggagg tagatctttc tctcaaccac atctgcctcc acacacagct 5300

 cctccgcagg gaaggagaag ctgctctgta actcattctg gctatcgtcc 5350

 cccttctcac tgacctgacc gcccaccacc tccttccccc tcatcacatg 5400

 acaaaggata atgtgcaaga aaagtatttt tatgtatcat aaatgtattt 5450

 tgaaacaaat gagaagaaga aaggtagaag ggtttatttt attaaatgag 5500

 cctgacttag tgacagtgtg tgagcatttg caatgtaagg gcctcagctt 5550

 ccttggagaa gccaccccag gtttccagac atagatgttg aattgtttgt 5600

 ggggggtgtg ccaggccacg tctcgtgtgt ccgtatgcag gcatgcctgt 5650

 gtatactgtg tatgggcaca ctgtgggact agctgggaca attcctagag 5700

 attcaactgc ccaattctaa ccaacattgg cagcggctga acttggcatt 5750

 tccttgctaa ctgccagatg tggccaacct ttgtccatat gcaaaccact 5800

 gaaaaatgat ctggatttct atagcaaggc ccttggggag ggcactctcc 5850

 catgcccttg gcctcgctgg ccacattggc caatgagcca gggctggagt 5900

 ctgagacctt tggttgttct ttaaggcacc tcctgccact ttctccctca 5950

 gaggcacaaa cactttgtgt tccacgtcag tttgagggga cggtgggggg 6000

 atgatatgaa tgtcacagga ggagacacct tctgtctttg tttcaaagaa 6050

 agtgatgtgc catttgttaa tatacaagag aaatattgaa aatatattga 6100

 aaagagcaat tttaaattat ttttggctta tgttgcaata tttattttct 6150

 tgtattagaa aagattcctt tgtagagaaa aaatgtattt ttcattaacg 6200

 caaagaccta tttctccttt ttgtacattg tccatgtgcg caacccttaa 6250

 cgagcaatag aatgtatggt cacctgggtg tggccagtgc ccgctgtgcc 6300

 ctgcatgatt ctgtgttgcc gctgctgcat agttcccagc cccatcctgt 6350

 cctgctcact catgggggct tccagacccc ggccccacca gggcttgtgt 6400

 catagggagc cctttgcact cctcgtgtgt tggcaaacgc agttaataaa 6450

 gcaatgtttt ctgtgc 6466

<210> 2651
<211> 681
<212> DNA
<213> Homo sapien

<400> 2651
 gaagacattg tggctgacca tgttgcctct tacggtgtaa acttgtacca 50

 gtcttatggt ccctctgggc agtacagcca tgaatttgat ggagacgagg 100

 agttctatgt ggacctggag aggaaggaga ctgtctggca gttgcctctg 150

 ttccgcagat ttagaagatt tgacccgcaa tttgcactga caaacatcgc 200

 tgtgctaaaa cataacttga acatcgtgat taaacgctcc aactctaccg 250

 ctgctaccaa tgaggttcct gaggtcacag tgttttccaa gtctcccgtg 300

 acactgggtc agcccaacac cctcatctgt cttgtggaca acatctttcc 350

 tcctgtggtc aacatcacct ggctgagcaa tgggcactca gtcacagaag 400

 gtgtttctga gaccagcttc ctctccaaga gtgatcattc cttcttcaag 450

 atcagttacc tcaccttcct cccttctgat gatgagattt atgactgcaa 500

 ggtggagcac tggggcctgg atgagcctct tctgaaacac tgggagcctg 550

 agattccaac acctatgtca gagctcacag agactgtggt ctgcgccctg 600

 gggttgtctg tgggcctcgt gggcattgtg gtggggaccg tcttgatcat 650

 ccgaggcctg cgttcagttg gtgcttccag a 681

<210> 2652
<211> 13708
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 10096-10440, 11382-11718, 12631-12691
<223> Unknown base

<400> 2652
 ctaacggaga aaagaagccg tggccgcggg aggaggcgag aggagtcggg 50

 atctgcgctg cagccaccgc cgcggttgat actactttga ccttccgagt 100

 gcagtggtag gggcgcggag gcaacgcagc ggcttctgcg ctgggaaatt 150

 cagtcgtgtg cgacccagtc tgtcctctcc ccagaccgcc aatctcatgc 200

 acccctccag agtggccctt gactcctccc tctcctcact ccatctttcc 250

 tggcctctct ccgggtgctt agcggacttg gccaataacc tcctcctttt 300

 aaacgccctg aattgaaccc tgcctcctgc gcatcctctt tttgtgtcac 350

 cttagggttc agatttaact acgcgacttg actagtcatc ttttgatctc 400

 tctctcgtat ttagtacttt tagtcagcga gcatttattg atatttcaac 450

 ttcagcctcg cggttaagag cttgggctct ggaatcatac ggctggaatt 500

 ggaattctgt cagtcgtgtg gccgctctct actgtcttgt gaagataagt 550

 gagataatct tgacctgtgg tgagcactcg tgagcgttag ctgctgtatt 600

 taccagaggc atacatcaca atttggaatt atgcattggt ttatcaattt 650

 acttgtttat tgtcaccctg ctgcccagat atgacttcat gagggacagt 700

 gatgtgtgtt ctgaaattgt gaaccatgag tctagtactt aatgatctgc 750

 ttatctgctg ccgtcaacta gaacatgata gagctacaga acgaaagaaa 800

 gaagttgaga aatttaagcg cctgattcga gatcctgaaa caattaaaca 850

 tctagatcgg cattcagatt ccaaacaagg aaaatatttg aattgggatg 900

 ctgtttttag atttttacag aaatatattc agaaagaaac agaatgtctg 950

 agaatagcaa aaccaaatgt atcagcctca acacaagcct ccaggcagaa 1000

 aaagatgcag gaaatcagta gtttggtcaa atacttcatc aaatgtgcaa 1050

 acagaagagc acctaggcta aaatgtcaag aactcttaaa ttatatcatg 1100

 gatacagtga aagattcatc taatggtgct atttacggag ctgattgtag 1150

 caacatacta ctcaaagaca ttctttctgt gagaaaatac tggtgtgaaa 1200

 tatctcagca acagtggtta gaattgttct ctgtgtactt caggctctat 1250

 ctgaaacctt cacaagatgt tcatagagtt ttagtggcta gaataattca 1300

 tgctgttacc aaaggatgct gttctcagac tgacggatta aattccaaat 1350

 ttttggactt tttttccaag gctattcagt gtgcgagaca agaaaagagc 1400

 tcttcaggtc taaatcatat cttagcagct cttactatct tcctcaagac 1450

 tttggctgtc aactttcgaa ttcgagtgtg tgaattagga gatgaaattc 1500

 ttcccacttt gctttatatt tggactcaac ataggcttaa tgattcttta 1550

 aaagaagtca ttattgaatt atttcaactg caaatttata tccatcatcc 1600

 gaaaggagcc aaaacccaag aaaaaggtgc ttatgaatca acaaaatgga 1650

 gaagtatttt atacaactta tatgatctgc tagtgaatga gataagtcat 1700

 ataggaagta gaggaaagta ttcttcagga tttcgtaata ttgccgtcaa 1750

 agaaaatttg attgaattga tggcagatat ctgtcaccag gtttttaatg 1800

 aagataccag atccttggag atttctcaat cttacactac tacacaaaga 1850

 gaatctagtg attacagtgt cccttgcaaa aggaagaaaa tagaactagg 1900

 ctgggaagta ataaaagatc accttcagaa gtcacagaat gattttgatc 1950

 ttgtgccttg gctacagatt gcaacccaat taatatcaaa gtatcctgca 2000

 agtttaccta actgtgagct gtctccatta ctgatgatac tatctcagct 2050

 tctaccccaa cagcgacatg gggaacgtac accatatgtg ttacgatgcc 2100

 ttacggaagt tgcattgtgt caagacaaga ggtcaaacct agaaagctca 2150

 caaaagtcag atttattaaa actctggaat aaaatttggt gtattacctt 2200

 tcgtggtata agttctgagc aaatacaagc tgaaaacttt ggcttacttg 2250

 gagccataat tcagggtagt ttagttgagg ttgacagaga attctggaag 2300

 ttatttactg ggtcagcctg cagaccttca tgtcctgcag tatgctgttt 2350

 gactttggca ctgaccacca gtatagttcc aggagcggta aaaatgggaa 2400

 tagagcaaaa tatgtgtgaa gtaaatagaa gcttttcttt aaaggaatca 2450

 ataatgaaat ggctcttatt ctatcagtta gagggtgact tagaaaatag 2500

 cacagaagtg cctccaattc ttcacagtaa ttttcctcat cttgtactgg 2550

 agaaaattct tgtgagtctc actatgaaaa actgtaaagc tgcaatgaat 2600

 tttttccaaa gcgtgccaga atgtgaacac caccaaaaag ataaagaaga 2650

 actttcattc tcagaagtag aagaactatt tcttcagaca acttttgaca 2700

 agatggactt tttaaccatt gtgagagaat gtggtataga aaagcaccag 2750

 tccagtattg gcttctctgt ccaccagaat ctcaaggaat cactggatcg 2800

 ctgtcttctg ggattatcag aacagcttct gaataattac tcatctgaga 2850

 ttacaaattc agaaactctt gtccggtgtt cacgtctttt ggtgggtgtc 2900

 cttggctgct actgttacat gggtgtaata gctgaagagg aagcatataa 2950

 gtcagaatta ttccagaaag ccaactctct aatgcaatgt gcaggagaaa 3000

 gtatcactct gtttaaaaat aagacaaatg aggaattcag aattggttcc 3050

 ttgagaaata tgatgcagct atgtacacgt tgcttgagca actgtaccaa 3100

 gaagagtcca aataagattg catctggctt tttcctgcga ttgttaacat 3150

 caaagctaat gaatgacatt gcagatattt gtaaaagttt agcatccttc 3200

 atcaaaaagc catttgaccg tggagaagta gaatcaatgg aagatgatac 3250

 taatggaaat ctaatggagg tggaggatca gtcatccatg aatctattta 3300

 acgattaccc tgatagtagt gttagtgatg caaacgaacc tggagagagc 3350

 caaagtacca taggtgccat taatccttta gctgaagaat atctgtcaaa 3400

 gcaagatcta cttttcttag acatgctcaa gttcttgtgt ttgtgtgtaa 3450

 ctactgctca gaccaatact gtgtccttta gggcagctga tattcggagg 3500

 aaattgttaa tgttaattga ttctagcacg ctagaaccta ccaaatccct 3550

 ccacctgcat atgtatctaa tgcttttaaa ggagcttcct ggagaagagt 3600

 accccttgcc aatggaagat gttcttgaac ttctgaaacc actatccaat 3650

 gtgtgttctt tgtatcgtcg tgaccaagat gtttgtaaaa ctattttaaa 3700

 ccatgtcctt catgtagtga aaaacctagg tcaaagcaat atggactctg 3750

 agaacacaag ggatgctcaa ggacagtttc ttacagtaat tggagcattt 3800

 tggcatctaa caaaggagag gaaatatata ttctctgtaa gaatggccct 3850

 agtaaattgc cttaaaactt tgcttgaggc tgatccttat tcaaaatggg 3900

 ccattcttaa tgtaatggga aaagactttc ctgtaaatga agtatttaca 3950

 caatttcttg ctgacaatca tcaccaagtt cgcatgttgg ctgcagagtc 4000

 aatcaataga ttgttccagg acacgaaggg agattcttcc aggttactga 4050

 aagcacttcc tttgaagctt cagcaaacag cttttgaaaa tgcatacttg 4100

 aaagctcagg aaggaatgag agaaatgtcc catagtgctg agaaccctga 4150

 aactttggat gaaatttata atagaaaatc tgttttactg acgttgatag 4200

 ctgtggtttt atcctgtagc cctatctgcg aaaaacaggc tttgtttgcc 4250

 ctgtgtaaat ctgtgaaaga gaatggatta gaacctcacc ttgtgaaaaa 4300

 ggttttagag aaagtttctg aaacttttgg atatagacgt ttagaagact 4350

 ttatggcatc tcatttagat tatctggttt tggaatggct aaatcttcaa 4400

 gatactgaat acaacttatc ttcttttcct tttattttat taaactacac 4450

 aaatattgag gatttctata gatcttgtta taaggttttg attccacatc 4500

 tggtgattag aagtcatttt gatgaggtga agtccattgc taatcagatt 4550

 caagaggact ggaaaagtct tctaacagac tgctttccaa agattcttgt 4600

 aaatattctt ccttattttg cctatgaggg taccagagac agtgggatgg 4650

 cacagcaaag agagactgct accaaggtct atgatatgct taaaagtgaa 4700

 aacttattgg gaaaacagat tgatcactta ttcattagta atttaccaga 4750

 gattgtggtg gagttattga tgacgttaca tgagccagca aattctagtg 4800

 ccagtcagag cactgacctc tgtgactttt caggggattt ggatcctgct 4850

 cctaatccac ctcattttcc atcgcatgtg attaaagcaa catttgccta 4900

 tatcagcaat tgtcataaaa ccaagttaaa aagcatttta gaaattcttt 4950

 ccaaaagccc tgattcctat cagaaaattc ttcttgccat atgtgagcaa 5000

 gcagctgaaa caaataatgt ttataagaag cacagaattc ttaaaatata 5050

 tcacctgttt gttagtttat tactgaaaga tataaaaagt ggcttaggag 5100

 gagcttgggc ctttgttctt cgagacgtta tttatacttt gattcactat 5150

 atcaaccaaa ggccttcttg tatcatggat gtgtcattac gtagcttctc 5200

 cctttgttgt gacttattaa gtcaggtttg ccagacagcc gtgacttact 5250

 gtaaggatgc tctagaaaac catcttcatg ttattgttgg tacacttata 5300

 ccccttgtgt atgagcaggt ggaggttcag aaacaggtat tggacttgtt 5350

 gaaatactta gtgatagata acaaggataa tgaaaacctc tatatcacga 5400

 ttaagctttt agatcctttt cctgaccatg ttgtttttaa ggatttgcgt 5450

 attactcagc aaaaaatcaa atacagtaga ggaccctttt cactcttgga 5500

 ggaaattaac cattttctct cagtaagtgt ttatgatgca cttccattga 5550

 caagacttga aggactaaag gatcttcgaa gacaactgga actacataaa 5600

 gatcagatgg tggacattat gagagcttct caggataatc cgcaagatgg 5650

 gattatggtg aaactagttg tcaatttgtt gcagttatcc aagatggcaa 5700

 taaaccacac tggtgaaaaa gaagttctag aggctgttgg aagctgcttg 5750

 ggagaagtgg gtcctataga tttctctacc atagctatac aacatagtaa 5800

 agatgcatct tataccaagg cccttaagtt atttgaagat aaagaacttc 5850

 agtggacctt cataatgctg acctacctga ataacacact ggtagaagat 5900

 tgtgtcaaag ttcgatcagc agctgttacc tgtttgaaaa acattttagc 5950

 cacaaagact ggacatagtt tctgggagat ttataagatg acaacagatc 6000

 caatgctggc ctatctacag ccttttagaa catcaagaaa aaagttttta 6050

 gaagtaccca gatttgacaa agaaaaccct tttgaaggcc tggatgatat 6100

 aaatctgtgg attcctctaa gtgaaaatca tgacatttgg ataaagacac 6150

 tgacttgtgc ttttttggac agtggaggca caaaatgtga aattcttcaa 6200

 ttattaaagc caatgtgtga agtgaaaact gacttttgtc agactgtact 6250

 tccatacttg attcatgata ttttactcca agatacaaat gaatcatgga 6300

 gaaatctgct ttctacacat gttcagggat ttttcaccag ctgtcttcga 6350

 cacttctcgc aaacgagccg atccacaacc cctgcaaact tggattcaga 6400

 gtcagagcac tttttccgat gctgtttgga taaaaaatca caaagaacaa 6450

 tgcttgctgt tgtggactac atgagaagac aaaagagacc ttcttcagga 6500

 acaattttta atgatgcttt ctggctggat ttaaattatc tagaagttgc 6550

 caaggtagct cagtcttgtg ctgctcactt tacagcttta ctctatgcag 6600

 aaatctatgc agataagaaa agtatggatg atcaagagaa aagaagtctt 6650

 gcatttgaag aaggaagcca gagtacaact atttctagct tgagtgaaaa 6700

 aagtaaagaa gaaactggaa taagtttaca ggatcttctc ttagaaatct 6750

 acagaagtat aggggagcca gatagtttgt atggctgtgg tggagggaag 6800

 atgttacaac ccattactag actacgaaca tatgaacacg aagcaatgtg 6850

 gggcaaagcc ctagtaacat atgacctcga aacagcaatc ccctcatcaa 6900

 cacgccaggc aggaatcatt caggccttgc agaatttggg actctgccat 6950

 attctttccg tctatttaaa aggattggat tatgaaaata aagactggtg 7000

 tcctgaacta gaagaacttc attaccaagc agcatggagg aatatgcagt 7050

 gggaccattg cacttccgtc agcaaagaag tagaaggaac cagttaccat 7100

 gaatcattgt acaatgctct acaatctcta agagacagag aattctctac 7150

 attttatgaa agtctcaaat atgccagagt aaaagaagtg gaagagatgt 7200

 gtaagcgcag ccttgagtct gtgtattcgc tctatcccac acttagcagg 7250

 ttgcaggcca ttggagagct ggaaagcatt ggggagcttt tctcaagatc 7300

 agtcacacat agacaactct ctgaagtata tattaagtgg cagaaacact 7350

 cccagcttct caaggacagt gattttagtt ttcaggagcc tatcatggct 7400

 ctacgcacag tcattttgga gatcctgatg gaaaaggaaa tggacaactc 7450

 acaaagagaa tgtattaagg acattctcac caaacacctt gtagaactct 7500

 ctatactggc cagaactttc aagaacactc agctccctga aagggcaata 7550

 tttcaaatta aacagtacaa ttcagttagc tgtggagtct ctgagtggca 7600

 gctggaagaa gcacaagtat tctgggcaaa aaaggagcag agtcttgccc 7650

 tgagtattct caagcaaatg atcaagaagt tggatgccag ctgtgcagcg 7700

 aacaatccca gcctaaaact tacatacaca gaatgtctga gggtttgtgg 7750

 caactggtta gcagaaacgt gcttagaaaa tcctgcggtc atcatgcaga 7800

 cctatctaga aaaggcagta gaagttgctg gaaattatga tggagaaagt 7850

 agtgatgagc taagaaatgg aaaaatgaag gcatttctct cattagcccg 7900

 gttttcagat actcaatacc aaagaattga aaactacatg aaatcatcgg 7950

 aatttgaaaa caagcaagct ctcctgaaaa gagccaaaga ggaagtaggt 8000

 ctccttaggg aacataaaat tcagacaaac agatacacag taaaggttca 8050

 gcgagagctg gagttggatg aattagccct gcgtgcactg aaagaggatc 8100

 gtaaacgctt cttatgtaaa gcagttgaaa attatatcaa ctgcttatta 8150

 agtggagaag aacatgatat gtgggtattc cgactttgtt ccctctggct 8200

 tgaaaattct ggagtttctg aagtcaatgg catgatgaag agagacggaa 8250

 tgaagattcc aacatataaa tttttgcctc ttatgtacca attggctgct 8300

 agaatgggga ccaagatgat gggaggccta ggatttcatg aagtcctcaa 8350

 taatctaatc tctagaattt caatggatca cccccatcac actttgttta 8400

 ttatactggc cttagcaaat gcaaacagag atgaatttct gactaaacca 8450

 gaggtagcca gaagaagcag aataactaaa aatgtgccta aacaaagctc 8500

 tcagcttgat gaggatcgaa cagaggctgc aaatagaata atatgtacta 8550

 tcagaagtag gagacctcag atggtcagaa gtgttgaggc actttgtgat 8600

 gcttatatta tattagcaaa cttagatgcc actcagtgga agactcagag 8650

 aaaaggcata aatattccag cagaccagcc aattactaaa cttaagaatt 8700

 tagaagatgt tgttgtccct actatggaaa ttaaggtgga ccacacagga 8750

 gaatatggaa atctggtgac tatacagtca tttaaagcag aatttcgctt 8800

 agcaggaggt gtaaatttac caaaaataat agattgtgta ggttccgatg 8850

 gcaaggagag gagacagctt gttaagggcc gtgatgacct gagacaagat 8900

 gctgtcatgc aacaggtctt ccagatgtgt aatacattac tgcagagaaa 8950

 cacggaaact aggaagagga aattaactat ctgtacttat aaggtggttc 9000

 ccctctctca gcgaagtggt gttcttgaat ggtgcacagg aactgtcccc 9050

 attggtgaat ttcttgttaa caatgaagat ggtgctcata aaagatacag 9100

 gccaaatgat ttcagtgcct ttcagtgcca aaagaaaatg atggaggtgc 9150

 aaaaaaagtc ttttgaagag aaatatgaag tcttcatgga tgtttgccaa 9200

 aattttcaac cagttttccg ttacttctgc atggaaaaat tcttggatcc 9250

 agctatttgg tttgagaagc gattggctta tacgcgcagt gtagctactt 9300

 cttctattgt tggttacata cttggacttg gtgatagaca tgtacagaat 9350

 atcttgataa atgagcagtc agcagaactt gtacatatag atctaggtgt 9400

 tgcttttgaa cagggcaaaa tccttcctac tcctgagaca gttcctttta 9450

 gactcaccag agatattgtg gatggcatgg gcattacggg tgttgaaggt 9500

 gtcttcagaa gatgctgtga gaaaaccatg gaagtgatga gaaactctca 9550

 ggaaactctg ttaaccattg tagaggtcct tctatatgat ccactctttg 9600

 actggaccat gaatcctttg aaagctttgt atttacagca gaggccggaa 9650

 gatgaaactg agcttcaccc tactctgaat gcagatgacc aagaatgcaa 9700

 acgaaatctc agtgatattg accagagttt caacaaagta gctgaacgtg 9750

 tcttaatgag actacaagag aaactgaaag gagtggaaga aggcactgtg 9800

 ctcagtgttg gtggacaagt gaatttgctc atacagcagg ccatagaccc 9850

 caaaaatctc agccgacttt tcccaggatg gaaagcttgg gtgtgatctt 9900

 cagtatatga attacccttt cattcagcct ttagaaatta tattttagcc 9950

 tttattttta acctgccaac atactttaag tagggattaa tatttaagtg 10000

 aactattgtg ggtttttttg aatgttggtt ttaatacttg atttaatcac 10050

 cactcaaaaa tgtttgatgg gcctaaggga catctctgct ttcacnnnnn 10100

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10150

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cttatttgga 10450

 tttttcctag taagatcact cagtgttact aaataatgaa gttgttatgg 10500

 agaacaaatt tcaaagacac agttagtgta gttactattt ttttaagtgt 10550

 gtattaaaac ttctcattct attctcttta tcttttaagc ccttctgtac 10600

 tgtccatgta tgttatcttt ctgtgataac ttcatagatt gccttctagt 10650

 tcatgaattc tcttgtcaga tgtatataat ctcttttacc ctatccattg 10700

 ggcttcttct ttcagaaatt gtttttcatt tctaattatg catcattttt 10750

 cagatctctg tttcttgatg tcatttttaa tgttttttta atgtttttta 10800

 tgtcactaat tattttaaat gtctgtacct gatagacact gtaatagttc 10850

 tattaaattt agttcctgct gtttatatct gttgattttt gtatttgata 10900

 ggctgttcat ccagttttgt ctttttgaaa agtgagttta ttttcagcaa 10950

 ggctttatct atgggaatct tgagtgtctg tttatgtcat attcccaggg 11000

 ctgttgctgc acacaagccc attcttattt taatttcttg gctttagggt 11050

 ttccatacct gaagtgtagc ataaatactg ataggagatt tcccaggcca 11100

 aggcaaacac acttcctcct catctccttg tgctagtggg cagaatattt 11150

 gattgatgcc tttttcactg agagtataag cttccatgtg tcccaccttt 11200

 atggcagggg tggaaggagg tacatttaat tcccactgcc tgcctttggc 11250

 aagccctggg ttctttgctc cccatataga tgtctaagct aaaagccgtg 11300

 ggttaatgag actggcaaat tgttccagga cagctacagc atcagctcac 11350

 atattcacct ctctggtttt tcattcccct cnnnnnnnnn nnnnnnnnnn 11400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11650

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11700

 nnnnnnnnnn nnnnnnnntt ctgctatgta tttaaaagaa tgttttctac 11750

 attttatcca gcatttctct gtgttctgtt ggaagggaag ggcttaggta 11800

 tctagtttga tacataggta gaagtggaac atttctctgt cccccagctg 11850

 tcatcatata agataaacat cagataaaaa gccacctgaa agtaaaacta 11900

 ctgactcgtg tattagtgag tataatctct tctccatcct taggaaaatg 11950

 ttcatcccag ctgcggagat taacaaatgg gtgattgagc tttctcctcg 12000

 tatttggacc ttgaaggtta tataaatttt tttcttatga agagttggca 12050

 tttcttttta ttgccaatgg caggcactca ttcatatttg atctcctcac 12100

 cttcccctcc cctaaaacca atctccagaa ctttttggac tataaatttc 12150

 ttggtttgac ttctggagaa ctgttcagaa tattactttg catttcaaat 12200

 tacaaactta ccttggtgta tctttttctt acaagctgcc taaatgaata 12250

 tttggtatat attggtagtt ttattactat agtaaatcaa ggaaatgcag 12300

 taaacttaaa atgtctttaa gaaagccctg aaatcttcat gggtgaaatt 12350

 agaaattatc aactagataa tagtatagat aaatgaattt gtagctaatt 12400

 cttgctagtt gttgcatcca gagagctttg aataacatca ttaatctact 12450

 ctttagcctt gcatggtatg ctatgaggct cctgttctgt tcaagtattc 12500

 taatcaatgg ctttgaaaag tttatcaaat ttacatacag atcacaagcc 12550

 taggagaaat aactaattca cagatgacag aattaagatt ataaaagatt 12600

 ttttttttgt aattttagta gagacagggt nnnnnnnnnn nnnnnnnnnn 12650

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nggttttggc 12700

 aagctggaac tctttctgca aatgactaag atagaaaact gccaaggaca 12750

 aatgaggagt agttagattt tgaaaatatt aatcatagaa tagttgttgt 12800

 atgctaagtc actgacccat attatgtaca gcatttctga tctttacttt 12850

 gcaagattag tgatactatc ccaatacact gctggagaaa tcagaatttg 12900

 gagaaataag ttgtccaagg caagaagata gtaaattata agtacaagtg 12950

 taatatggac agtatctaac ttgaaaagat ttcaggcgaa aagaatctgg 13000

 ggtttgccag tcagttgctc aaaaggtcaa tgaaaaccaa atagtgaagc 13050

 tatcagagaa gctaataaat tatagactgc ttgaacagtt gtgtccagat 13100

 taagggagat aatagctttc ccaccctact ttgtgcaggt catacctccc 13150

 caaagtgttt acctaatcag taggttcaca aactcttggt cattatagta 13200

 tatgcctaaa atgtatgcac ttaggaatgc taaaaattta aatatggtct 13250

 aaagcaaata aaagcaaaga ggaaaaactt tggacatcgt aaagactaga 13300

 atagtctttt aaaaagaaag ccagtatatt ggtttgaaat atagagatgt 13350

 gtcccaattt caagtatttt aattgcacct taatgaaatt atctattttc 13400

 tatagatttt agtactattg aatgtattac tttactgtta cctgaattta 13450

 ttataaagtg tttttgaata aataattcta aaagcatata ctaagactca 13500

 ttcactttat tcaaatattt gtgtgttctg tgtgccaggc atgggactcg 13550

 ttctaaggag aaagcagtga gcaaggcagg catagtctgc ctatataaag 13600

 ctcccaatct gaggaggata ggcaactgac cacgcagtgt gaaccgggga 13650

 gcctattgca caaccagtct gataatgctg catctcagtc taaatatcct 13700

 agtagtgt 13708

<210> 2653
<211> 3056
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 10096-10440, 11382-11718, 12631-12691
<223> Unknown amino acid

<400> 2653
 Met Ser Leu Val Leu Asn Asp Leu Leu Ile Cys Cys Arg Gln Leu
   1               5                  10                  15

 Glu His Asp Arg Ala Thr Glu Arg Lys Lys Glu Val Glu Lys Phe
                  20                  25                  30

 Lys Arg Leu Ile Arg Asp Pro Glu Thr Ile Lys His Leu Asp Arg
                  35                  40                  45

 His Ser Asp Ser Lys Gln Gly Lys Tyr Leu Asn Trp Asp Ala Val
                  50                  55                  60

 Phe Arg Phe Leu Gln Lys Tyr Ile Gln Lys Glu Thr Glu Cys Leu
                  65                  70                  75

 Arg Ile Ala Lys Pro Asn Val Ser Ala Ser Thr Gln Ala Ser Arg
                  80                  85                  90

 Gln Lys Lys Met Gln Glu Ile Ser Ser Leu Val Lys Tyr Phe Ile
                  95                 100                 105

 Lys Cys Ala Asn Arg Arg Ala Pro Arg Leu Lys Cys Gln Glu Leu
                 110                 115                 120

 Leu Asn Tyr Ile Met Asp Thr Val Lys Asp Ser Ser Asn Gly Ala
                 125                 130                 135

 Ile Tyr Gly Ala Asp Cys Ser Asn Ile Leu Leu Lys Asp Ile Leu
                 140                 145                 150

 Ser Val Arg Lys Tyr Trp Cys Glu Ile Ser Gln Gln Gln Trp Leu
                 155                 160                 165

 Glu Leu Phe Ser Val Tyr Phe Arg Leu Tyr Leu Lys Pro Ser Gln
                 170                 175                 180

 Asp Val His Arg Val Leu Val Ala Arg Ile Ile His Ala Val Thr
                 185                 190                 195

 Lys Gly Cys Cys Ser Gln Thr Asp Gly Leu Asn Ser Lys Phe Leu
                 200                 205                 210

 Asp Phe Phe Ser Lys Ala Ile Gln Cys Ala Arg Gln Glu Lys Ser
                 215                 220                 225

 Ser Ser Gly Leu Asn His Ile Leu Ala Ala Leu Thr Ile Phe Leu
                 230                 235                 240

 Lys Thr Leu Ala Val Asn Phe Arg Ile Arg Val Cys Glu Leu Gly
                 245                 250                 255

 Asp Glu Ile Leu Pro Thr Leu Leu Tyr Ile Trp Thr Gln His Arg
                 260                 265                 270

 Leu Asn Asp Ser Leu Lys Glu Val Ile Ile Glu Leu Phe Gln Leu
                 275                 280                 285

 Gln Ile Tyr Ile His His Pro Lys Gly Ala Lys Thr Gln Glu Lys
                 290                 295                 300

 Gly Ala Tyr Glu Ser Thr Lys Trp Arg Ser Ile Leu Tyr Asn Leu
                 305                 310                 315

 Tyr Asp Leu Leu Val Asn Glu Ile Ser His Ile Gly Ser Arg Gly
                 320                 325                 330

 Lys Tyr Ser Ser Gly Phe Arg Asn Ile Ala Val Lys Glu Asn Leu
                 335                 340                 345

 Ile Glu Leu Met Ala Asp Ile Cys His Gln Val Phe Asn Glu Asp
                 350                 355                 360

 Thr Arg Ser Leu Glu Ile Ser Gln Ser Tyr Thr Thr Thr Gln Arg
                 365                 370                 375

 Glu Ser Ser Asp Tyr Ser Val Pro Cys Lys Arg Lys Lys Ile Glu
                 380                 385                 390

 Leu Gly Trp Glu Val Ile Lys Asp His Leu Gln Lys Ser Gln Asn
                 395                 400                 405

 Asp Phe Asp Leu Val Pro Trp Leu Gln Ile Ala Thr Gln Leu Ile
                 410                 415                 420

 Ser Lys Tyr Pro Ala Ser Leu Pro Asn Cys Glu Leu Ser Pro Leu
                 425                 430                 435

 Leu Met Ile Leu Ser Gln Leu Leu Pro Gln Gln Arg His Gly Glu
                 440                 445                 450

 Arg Thr Pro Tyr Val Leu Arg Cys Leu Thr Glu Val Ala Leu Cys
                 455                 460                 465

 Gln Asp Lys Arg Ser Asn Leu Glu Ser Ser Gln Lys Ser Asp Leu
                 470                 475                 480

 Leu Lys Leu Trp Asn Lys Ile Trp Cys Ile Thr Phe Arg Gly Ile
                 485                 490                 495

 Ser Ser Glu Gln Ile Gln Ala Glu Asn Phe Gly Leu Leu Gly Ala
                 500                 505                 510

 Ile Ile Gln Gly Ser Leu Val Glu Val Asp Arg Glu Phe Trp Lys
                 515                 520                 525

 Leu Phe Thr Gly Ser Ala Cys Arg Pro Ser Cys Pro Ala Val Cys
                 530                 535                 540

 Cys Leu Thr Leu Ala Leu Thr Thr Ser Ile Val Pro Gly Ala Val
                 545                 550                 555

 Lys Met Gly Ile Glu Gln Asn Met Cys Glu Val Asn Arg Ser Phe
                 560                 565                 570

 Ser Leu Lys Glu Ser Ile Met Lys Trp Leu Leu Phe Tyr Gln Leu
                 575                 580                 585

 Glu Gly Asp Leu Glu Asn Ser Thr Glu Val Pro Pro Ile Leu His
                 590                 595                 600

 Ser Asn Phe Pro His Leu Val Leu Glu Lys Ile Leu Val Ser Leu
                 605                 610                 615

 Thr Met Lys Asn Cys Lys Ala Ala Met Asn Phe Phe Gln Ser Val
                 620                 625                 630

 Pro Glu Cys Glu His His Gln Lys Asp Lys Glu Glu Leu Ser Phe
                 635                 640                 645

 Ser Glu Val Glu Glu Leu Phe Leu Gln Thr Thr Phe Asp Lys Met
                 650                 655                 660

 Asp Phe Leu Thr Ile Val Arg Glu Cys Gly Ile Glu Lys His Gln
                 665                 670                 675

 Ser Ser Ile Gly Phe Ser Val His Gln Asn Leu Lys Glu Ser Leu
                 680                 685                 690

 Asp Arg Cys Leu Leu Gly Leu Ser Glu Gln Leu Leu Asn Asn Tyr
                 695                 700                 705

 Ser Ser Glu Ile Thr Asn Ser Glu Thr Leu Val Arg Cys Ser Arg
                 710                 715                 720

 Leu Leu Val Gly Val Leu Gly Cys Tyr Cys Tyr Met Gly Val Ile
                 725                 730                 735

 Ala Glu Glu Glu Ala Tyr Lys Ser Glu Leu Phe Gln Lys Ala Asn
                 740                 745                 750

 Ser Leu Met Gln Cys Ala Gly Glu Ser Ile Thr Leu Phe Lys Asn
                 755                 760                 765

 Lys Thr Asn Glu Glu Phe Arg Ile Gly Ser Leu Arg Asn Met Met
                 770                 775                 780

 Gln Leu Cys Thr Arg Cys Leu Ser Asn Cys Thr Lys Lys Ser Pro
                 785                 790                 795

 Asn Lys Ile Ala Ser Gly Phe Phe Leu Arg Leu Leu Thr Ser Lys
                 800                 805                 810

 Leu Met Asn Asp Ile Ala Asp Ile Cys Lys Ser Leu Ala Ser Phe
                 815                 820                 825

 Ile Lys Lys Pro Phe Asp Arg Gly Glu Val Glu Ser Met Glu Asp
                 830                 835                 840

 Asp Thr Asn Gly Asn Leu Met Glu Val Glu Asp Gln Ser Ser Met
                 845                 850                 855

 Asn Leu Phe Asn Asp Tyr Pro Asp Ser Ser Val Ser Asp Ala Asn
                 860                 865                 870

 Glu Pro Gly Glu Ser Gln Ser Thr Ile Gly Ala Ile Asn Pro Leu
                 875                 880                 885

 Ala Glu Glu Tyr Leu Ser Lys Gln Asp Leu Leu Phe Leu Asp Met
                 890                 895                 900

 Leu Lys Phe Leu Cys Leu Cys Val Thr Thr Ala Gln Thr Asn Thr
                 905                 910                 915

 Val Ser Phe Arg Ala Ala Asp Ile Arg Arg Lys Leu Leu Met Leu
                 920                 925                 930

 Ile Asp Ser Ser Thr Leu Glu Pro Thr Lys Ser Leu His Leu His
                 935                 940                 945

 Met Tyr Leu Met Leu Leu Lys Glu Leu Pro Gly Glu Glu Tyr Pro
                 950                 955                 960

 Leu Pro Met Glu Asp Val Leu Glu Leu Leu Lys Pro Leu Ser Asn
                 965                 970                 975

 Val Cys Ser Leu Tyr Arg Arg Asp Gln Asp Val Cys Lys Thr Ile
                 980                 985                 990

 Leu Asn His Val Leu His Val Val Lys Asn Leu Gly Gln Ser Asn
                 995                1000                1005

 Met Asp Ser Glu Asn Thr Arg Asp Ala Gln Gly Gln Phe Leu Thr
                1010                1015                1020

 Val Ile Gly Ala Phe Trp His Leu Thr Lys Glu Arg Lys Tyr Ile
                1025                1030                1035

 Phe Ser Val Arg Met Ala Leu Val Asn Cys Leu Lys Thr Leu Leu
                1040                1045                1050

 Glu Ala Asp Pro Tyr Ser Lys Trp Ala Ile Leu Asn Val Met Gly
                1055                1060                1065

 Lys Asp Phe Pro Val Asn Glu Val Phe Thr Gln Phe Leu Ala Asp
                1070                1075                1080

 Asn His His Gln Val Arg Met Leu Ala Ala Glu Ser Ile Asn Arg
                1085                1090                1095

 Leu Phe Gln Asp Thr Lys Gly Asp Ser Ser Arg Leu Leu Lys Ala
                1100                1105                1110

 Leu Pro Leu Lys Leu Gln Gln Thr Ala Phe Glu Asn Ala Tyr Leu
                1115                1120                1125

 Lys Ala Gln Glu Gly Met Arg Glu Met Ser His Ser Ala Glu Asn
                1130                1135                1140

 Pro Glu Thr Leu Asp Glu Ile Tyr Asn Arg Lys Ser Val Leu Leu
                1145                1150                1155

 Thr Leu Ile Ala Val Val Leu Ser Cys Ser Pro Ile Cys Glu Lys
                1160                1165                1170

 Gln Ala Leu Phe Ala Leu Cys Lys Ser Val Lys Glu Asn Gly Leu
                1175                1180                1185

 Glu Pro His Leu Val Lys Lys Val Leu Glu Lys Val Ser Glu Thr
                1190                1195                1200

 Phe Gly Tyr Arg Arg Leu Glu Asp Phe Met Ala Ser His Leu Asp
                1205                1210                1215

 Tyr Leu Val Leu Glu Trp Leu Asn Leu Gln Asp Thr Glu Tyr Asn
                1220                1225                1230

 Leu Ser Ser Phe Pro Phe Ile Leu Leu Asn Tyr Thr Asn Ile Glu
                1235                1240                1245

 Asp Phe Tyr Arg Ser Cys Tyr Lys Val Leu Ile Pro His Leu Val
                1250                1255                1260

 Ile Arg Ser His Phe Asp Glu Val Lys Ser Ile Ala Asn Gln Ile
                1265                1270                1275

 Gln Glu Asp Trp Lys Ser Leu Leu Thr Asp Cys Phe Pro Lys Ile
                1280                1285                1290

 Leu Val Asn Ile Leu Pro Tyr Phe Ala Tyr Glu Gly Thr Arg Asp
                1295                1300                1305

 Ser Gly Met Ala Gln Gln Arg Glu Thr Ala Thr Lys Val Tyr Asp
                1310                1315                1320

 Met Leu Lys Ser Glu Asn Leu Leu Gly Lys Gln Ile Asp His Leu
                1325                1330                1335

 Phe Ile Ser Asn Leu Pro Glu Ile Val Val Glu Leu Leu Met Thr
                1340                1345                1350

 Leu His Glu Pro Ala Asn Ser Ser Ala Ser Gln Ser Thr Asp Leu
                1355                1360                1365

 Cys Asp Phe Ser Gly Asp Leu Asp Pro Ala Pro Asn Pro Pro His
                1370                1375                1380

 Phe Pro Ser His Val Ile Lys Ala Thr Phe Ala Tyr Ile Ser Asn
                1385                1390                1395

 Cys His Lys Thr Lys Leu Lys Ser Ile Leu Glu Ile Leu Ser Lys
                1400                1405                1410

 Ser Pro Asp Ser Tyr Gln Lys Ile Leu Leu Ala Ile Cys Glu Gln
                1415                1420                1425

 Ala Ala Glu Thr Asn Asn Val Tyr Lys Lys His Arg Ile Leu Lys
                1430                1435                1440

 Ile Tyr His Leu Phe Val Ser Leu Leu Leu Lys Asp Ile Lys Ser
                1445                1450                1455

 Gly Leu Gly Gly Ala Trp Ala Phe Val Leu Arg Asp Val Ile Tyr
                1460                1465                1470

 Thr Leu Ile His Tyr Ile Asn Gln Arg Pro Ser Cys Ile Met Asp
                1475                1480                1485

 Val Ser Leu Arg Ser Phe Ser Leu Cys Cys Asp Leu Leu Ser Gln
                1490                1495                1500

 Val Cys Gln Thr Ala Val Thr Tyr Cys Lys Asp Ala Leu Glu Asn
                1505                1510                1515

 His Leu His Val Ile Val Gly Thr Leu Ile Pro Leu Val Tyr Glu
                1520                1525                1530

 Gln Val Glu Val Gln Lys Gln Val Leu Asp Leu Leu Lys Tyr Leu
                1535                1540                1545

 Val Ile Asp Asn Lys Asp Asn Glu Asn Leu Tyr Ile Thr Ile Lys
                1550                1555                1560

 Leu Leu Asp Pro Phe Pro Asp His Val Val Phe Lys Asp Leu Arg
                1565                1570                1575

 Ile Thr Gln Gln Lys Ile Lys Tyr Ser Arg Gly Pro Phe Ser Leu
                1580                1585                1590

 Leu Glu Glu Ile Asn His Phe Leu Ser Val Ser Val Tyr Asp Ala
                1595                1600                1605

 Leu Pro Leu Thr Arg Leu Glu Gly Leu Lys Asp Leu Arg Arg Gln
                1610                1615                1620

 Leu Glu Leu His Lys Asp Gln Met Val Asp Ile Met Arg Ala Ser
                1625                1630                1635

 Gln Asp Asn Pro Gln Asp Gly Ile Met Val Lys Leu Val Val Asn
                1640                1645                1650

 Leu Leu Gln Leu Ser Lys Met Ala Ile Asn His Thr Gly Glu Lys
                1655                1660                1665

 Glu Val Leu Glu Ala Val Gly Ser Cys Leu Gly Glu Val Gly Pro
                1670                1675                1680

 Ile Asp Phe Ser Thr Ile Ala Ile Gln His Ser Lys Asp Ala Ser
                1685                1690                1695

 Tyr Thr Lys Ala Leu Lys Leu Phe Glu Asp Lys Glu Leu Gln Trp
                1700                1705                1710

 Thr Phe Ile Met Leu Thr Tyr Leu Asn Asn Thr Leu Val Glu Asp
                1715                1720                1725

 Cys Val Lys Val Arg Ser Ala Ala Val Thr Cys Leu Lys Asn Ile
                1730                1735                1740

 Leu Ala Thr Lys Thr Gly His Ser Phe Trp Glu Ile Tyr Lys Met
                1745                1750                1755

 Thr Thr Asp Pro Met Leu Ala Tyr Leu Gln Pro Phe Arg Thr Ser
                1760                1765                1770

 Arg Lys Lys Phe Leu Glu Val Pro Arg Phe Asp Lys Glu Asn Pro
                1775                1780                1785

 Phe Glu Gly Leu Asp Asp Ile Asn Leu Trp Ile Pro Leu Ser Glu
                1790                1795                1800

 Asn His Asp Ile Trp Ile Lys Thr Leu Thr Cys Ala Phe Leu Asp
                1805                1810                1815

 Ser Gly Gly Thr Lys Cys Glu Ile Leu Gln Leu Leu Lys Pro Met
                1820                1825                1830

 Cys Glu Val Lys Thr Asp Phe Cys Gln Thr Val Leu Pro Tyr Leu
                1835                1840                1845

 Ile His Asp Ile Leu Leu Gln Asp Thr Asn Glu Ser Trp Arg Asn
                1850                1855                1860

 Leu Leu Ser Thr His Val Gln Gly Phe Phe Thr Ser Cys Leu Arg
                1865                1870                1875

 His Phe Ser Gln Thr Ser Arg Ser Thr Thr Pro Ala Asn Leu Asp
                1880                1885                1890

 Ser Glu Ser Glu His Phe Phe Arg Cys Cys Leu Asp Lys Lys Ser
                1895                1900                1905

 Gln Arg Thr Met Leu Ala Val Val Asp Tyr Met Arg Arg Gln Lys
                1910                1915                1920

 Arg Pro Ser Ser Gly Thr Ile Phe Asn Asp Ala Phe Trp Leu Asp
                1925                1930                1935

 Leu Asn Tyr Leu Glu Val Ala Lys Val Ala Gln Ser Cys Ala Ala
                1940                1945                1950

 His Phe Thr Ala Leu Leu Tyr Ala Glu Ile Tyr Ala Asp Lys Lys
                1955                1960                1965

 Ser Met Asp Asp Gln Glu Lys Arg Ser Leu Ala Phe Glu Glu Gly
                1970                1975                1980

 Ser Gln Ser Thr Thr Ile Ser Ser Leu Ser Glu Lys Ser Lys Glu
                1985                1990                1995

 Glu Thr Gly Ile Ser Leu Gln Asp Leu Leu Leu Glu Ile Tyr Arg
                2000                2005                2010

 Ser Ile Gly Glu Pro Asp Ser Leu Tyr Gly Cys Gly Gly Gly Lys
                2015                2020                2025

 Met Leu Gln Pro Ile Thr Arg Leu Arg Thr Tyr Glu His Glu Ala
                2030                2035                2040

 Met Trp Gly Lys Ala Leu Val Thr Tyr Asp Leu Glu Thr Ala Ile
                2045                2050                2055

 Pro Ser Ser Thr Arg Gln Ala Gly Ile Ile Gln Ala Leu Gln Asn
                2060                2065                2070

 Leu Gly Leu Cys His Ile Leu Ser Val Tyr Leu Lys Gly Leu Asp
                2075                2080                2085

 Tyr Glu Asn Lys Asp Trp Cys Pro Glu Leu Glu Glu Leu His Tyr
                2090                2095                2100

 Gln Ala Ala Trp Arg Asn Met Gln Trp Asp His Cys Thr Ser Val
                2105                2110                2115

 Ser Lys Glu Val Glu Gly Thr Ser Tyr His Glu Ser Leu Tyr Asn
                2120                2125                2130

 Ala Leu Gln Ser Leu Arg Asp Arg Glu Phe Ser Thr Phe Tyr Glu
                2135                2140                2145

 Ser Leu Lys Tyr Ala Arg Val Lys Glu Val Glu Glu Met Cys Lys
                2150                2155                2160

 Arg Ser Leu Glu Ser Val Tyr Ser Leu Tyr Pro Thr Leu Ser Arg
                2165                2170                2175

 Leu Gln Ala Ile Gly Glu Leu Glu Ser Ile Gly Glu Leu Phe Ser
                2180                2185                2190

 Arg Ser Val Thr His Arg Gln Leu Ser Glu Val Tyr Ile Lys Trp
                2195                2200                2205

 Gln Lys His Ser Gln Leu Leu Lys Asp Ser Asp Phe Ser Phe Gln
                2210                2215                2220

 Glu Pro Ile Met Ala Leu Arg Thr Val Ile Leu Glu Ile Leu Met
                2225                2230                2235

 Glu Lys Glu Met Asp Asn Ser Gln Arg Glu Cys Ile Lys Asp Ile
                2240                2245                2250

 Leu Thr Lys His Leu Val Glu Leu Ser Ile Leu Ala Arg Thr Phe
                2255                2260                2265

 Lys Asn Thr Gln Leu Pro Glu Arg Ala Ile Phe Gln Ile Lys Gln
                2270                2275                2280

 Tyr Asn Ser Val Ser Cys Gly Val Ser Glu Trp Gln Leu Glu Glu
                2285                2290                2295

 Ala Gln Val Phe Trp Ala Lys Lys Glu Gln Ser Leu Ala Leu Ser
                2300                2305                2310

 Ile Leu Lys Gln Met Ile Lys Lys Leu Asp Ala Ser Cys Ala Ala
                2315                2320                2325

 Asn Asn Pro Ser Leu Lys Leu Thr Tyr Thr Glu Cys Leu Arg Val
                2330                2335                2340

 Cys Gly Asn Trp Leu Ala Glu Thr Cys Leu Glu Asn Pro Ala Val
                2345                2350                2355

 Ile Met Gln Thr Tyr Leu Glu Lys Ala Val Glu Val Ala Gly Asn
                2360                2365                2370

 Tyr Asp Gly Glu Ser Ser Asp Glu Leu Arg Asn Gly Lys Met Lys
                2375                2380                2385

 Ala Phe Leu Ser Leu Ala Arg Phe Ser Asp Thr Gln Tyr Gln Arg
                2390                2395                2400

 Ile Glu Asn Tyr Met Lys Ser Ser Glu Phe Glu Asn Lys Gln Ala
                2405                2410                2415

 Leu Leu Lys Arg Ala Lys Glu Glu Val Gly Leu Leu Arg Glu His
                2420                2425                2430

 Lys Ile Gln Thr Asn Arg Tyr Thr Val Lys Val Gln Arg Glu Leu
                2435                2440                2445

 Glu Leu Asp Glu Leu Ala Leu Arg Ala Leu Lys Glu Asp Arg Lys
                2450                2455                2460

 Arg Phe Leu Cys Lys Ala Val Glu Asn Tyr Ile Asn Cys Leu Leu
                2465                2470                2475

 Ser Gly Glu Glu His Asp Met Trp Val Phe Arg Leu Cys Ser Leu
                2480                2485                2490

 Trp Leu Glu Asn Ser Gly Val Ser Glu Val Asn Gly Met Met Lys
                2495                2500                2505

 Arg Asp Gly Met Lys Ile Pro Thr Tyr Lys Phe Leu Pro Leu Met
                2510                2515                2520

 Tyr Gln Leu Ala Ala Arg Met Gly Thr Lys Met Met Gly Gly Leu
                2525                2530                2535

 Gly Phe His Glu Val Leu Asn Asn Leu Ile Ser Arg Ile Ser Met
                2540                2545                2550

 Asp His Pro His His Thr Leu Phe Ile Ile Leu Ala Leu Ala Asn
                2555                2560                2565

 Ala Asn Arg Asp Glu Phe Leu Thr Lys Pro Glu Val Ala Arg Arg
                2570                2575                2580

 Ser Arg Ile Thr Lys Asn Val Pro Lys Gln Ser Ser Gln Leu Asp
                2585                2590                2595

 Glu Asp Arg Thr Glu Ala Ala Asn Arg Ile Ile Cys Thr Ile Arg
                2600                2605                2610

 Ser Arg Arg Pro Gln Met Val Arg Ser Val Glu Ala Leu Cys Asp
                2615                2620                2625

 Ala Tyr Ile Ile Leu Ala Asn Leu Asp Ala Thr Gln Trp Lys Thr
                2630                2635                2640

 Gln Arg Lys Gly Ile Asn Ile Pro Ala Asp Gln Pro Ile Thr Lys
                2645                2650                2655

 Leu Lys Asn Leu Glu Asp Val Val Val Pro Thr Met Glu Ile Lys
                2660                2665                2670

 Val Asp His Thr Gly Glu Tyr Gly Asn Leu Val Thr Ile Gln Ser
                2675                2680                2685

 Phe Lys Ala Glu Phe Arg Leu Ala Gly Gly Val Asn Leu Pro Lys
                2690                2695                2700

 Ile Ile Asp Cys Val Gly Ser Asp Gly Lys Glu Arg Arg Gln Leu
                2705                2710                2715

 Val Lys Gly Arg Asp Asp Leu Arg Gln Asp Ala Val Met Gln Gln
                2720                2725                2730

 Val Phe Gln Met Cys Asn Thr Leu Leu Gln Arg Asn Thr Glu Thr
                2735                2740                2745

 Arg Lys Arg Lys Leu Thr Ile Cys Thr Tyr Lys Val Val Pro Leu
                2750                2755                2760

 Ser Gln Arg Ser Gly Val Leu Glu Trp Cys Thr Gly Thr Val Pro
                2765                2770                2775

 Ile Gly Glu Phe Leu Val Asn Asn Glu Asp Gly Ala His Lys Arg
                2780                2785                2790

 Tyr Arg Pro Asn Asp Phe Ser Ala Phe Gln Cys Gln Lys Lys Met
                2795                2800                2805

 Met Glu Val Gln Lys Lys Ser Phe Glu Glu Lys Tyr Glu Val Phe
                2810                2815                2820

 Met Asp Val Cys Gln Asn Phe Gln Pro Val Phe Arg Tyr Phe Cys
                2825                2830                2835

 Met Glu Lys Phe Leu Asp Pro Ala Ile Trp Phe Glu Lys Arg Leu
                2840                2845                2850

 Ala Tyr Thr Arg Ser Val Ala Thr Ser Ser Ile Val Gly Tyr Ile
                2855                2860                2865

 Leu Gly Leu Gly Asp Arg His Val Gln Asn Ile Leu Ile Asn Glu
                2870                2875                2880

 Gln Ser Ala Glu Leu Val His Ile Asp Leu Gly Val Ala Phe Glu
                2885                2890                2895

 Gln Gly Lys Ile Leu Pro Thr Pro Glu Thr Val Pro Phe Arg Leu
                2900                2905                2910

 Thr Arg Asp Ile Val Asp Gly Met Gly Ile Thr Gly Val Glu Gly
                2915                2920                2925

 Val Phe Arg Arg Cys Cys Glu Lys Thr Met Glu Val Met Arg Asn
                2930                2935                2940

 Ser Gln Glu Thr Leu Leu Thr Ile Val Glu Val Leu Leu Tyr Asp
                2945                2950                2955

 Pro Leu Phe Asp Trp Thr Met Asn Pro Leu Lys Ala Leu Tyr Leu
                2960                2965                2970

 Gln Gln Arg Pro Glu Asp Glu Thr Glu Leu His Pro Thr Leu Asn
                2975                2980                2985

 Ala Asp Asp Gln Glu Cys Lys Arg Asn Leu Ser Asp Ile Asp Gln
                2990                2995                3000

 Ser Phe Asn Lys Val Ala Glu Arg Val Leu Met Arg Leu Gln Glu
                3005                3010                3015

 Lys Leu Lys Gly Val Glu Glu Gly Thr Val Leu Ser Val Gly Gly
                3020                3025                3030

 Gln Val Asn Leu Leu Ile Gln Gln Ala Ile Asp Pro Lys Asn Leu
                3035                3040                3045

 Ser Arg Leu Phe Pro Gly Trp Lys Ala Trp Val
                3050                3055

<210> 2654
<211> 1069
<212> DNA
<213> Homo sapien

<400> 2654
 gaaaaccaga gcctatatgg agttccctct tctaacccaa ctgacttgta 50

 tctgtccgtg gaaaatttca gtccagaaga attgaccttg accattaata 100

 aagacactgg cagagagatc ttcccataat aaagcaatct gattcagcat 150

 cactaaaccg ataatgcatg aagcaacgat aaaattacaa aagagcagca 200

 tttttaattt tcacaaaatg tctcagtttt cagctatacc tgcacgttca 250

 taaccaacaa tataaaccgt ggtctcatgt aacacataaa caattcatgc 300

 ctttcatagt ttattattat taaagtctaa acaaaattgc aatttcttag 350

 gtaaccttat atttacaata aatgaagatt accctcaaat gctagaagct 400

 gtctaggtcc gtccggtgtg tcagattttc ctcagattag atgtgccaat 450

 aaccaagttt attcagtaaa caacttgtac ttgtttcatc tggttttatt 500

 actctcaccc ataaacagga atgactcttt gaccctctgg aaatatgtaa 550

 tgcttccaat cttgctttgt gtatctcatt taatttgtta taaggtagta 600

 ctgattttag catattaatg cgatttcttc cttgttgttt gctttggtct 650

 gtgttcaatc cagagagctt aaattgtcat tattttggga agaaaacctg 700

 tatttttgtt agtttacaat attatgaaat ttcacttcag gagaaactgc 750

 tgggcttcct gtggctttgt tttcttagtt actttttccg tgccgtgtat 800

 tttttaattg atttttcttc ttttacttga aaagaaagtg ttttattttc 850

 aaatctggtc catatttaca ttctagttca gagccaagcc ttaaactgta 900

 cagaatttcc actgtaatta aaactattta gtgttagtta taaatagcct 950

 tcaaaaagag agattctcca ttcacgatca cctgcatcac agcccatggt 1000

 gaatgtatgt ttctgcatag cgaaataaaa atggcaaatg caaaaaaaaa 1050

 aaaaaaaaaa aaaaaaaaa 1069

<210> 2655
<211> 6949
<212> DNA
<213> Homo sapien

<400> 2655
 aaacaagaag aatgggattg atatttccgc agaagtttgg aagttatgta 50

 acagagcagg ttgagatcct accttttagg agcagcctgc cccttttgaa 100

 ggggtaaagg gagtgggtgc agtgccctct cttctgttgt agtggcttat 150

 ccctctaagg catgaccctt ggataggggt tacctgcctc ggaaagtccc 200

 cacttccttg tgggagttta aaatagattg gcatatgtga gagatggaga 250

 caaggtggga aatcggatcc tgtcttagga tttctcatca ggagatgctg 300

 atacttggtg tttcagcttg ataaattgag aaggtgccat gaaaccaggt 350

 cctggaacag aatccctggt tgctctgtct tttagctgct ctgaccctct 400

 gccctgcaga gcatgcattt tgcatgtgcc tggcaggagg ccctcctgct 450

 tgagccctgc tgtatttgtc tgtgttgaca acgtgactgc cagccattaa 500

 gcttggtcag tccacagaca cactaggaaa gcagaggcag ctcttggttt 550

 ctctggaaca gagctgcaag aagtctctgg gcatctgcat ggccaggagc 600

 ttatgcttaa ctgttgagtg acctgcagcc ataagggcat taattctgcc 650

 ttccagaggt gggaatgact tggctttaaa cagtgatttg tgtgagaatt 700

 cttcaaatcc cataaggtag aaggcatggt ggagtggagg agaaatcttg 750

 gctcatatct gcctcttcca ttgaccagct gtgtgacctt gggcctgtta 800

 cttttaacct acctgaccct ccatttcctc atttatcaga agtgtctaac 850

 tgtacacaag ttaaactgta aggattacat gaggtagtag tcaatcctgg 900

 tgtttctctg tatcttctca cttctcactg gtgttggaaa tatgatcttg 950

 cgaccctaga tggcagccac tctggggcag aagagacagt gaccaccttt 1000

 tgaagagctc aaaggagaat attgccccac agggcttagt gggtccccca 1050

 ggctgaggct ggggaggagg gccacctttg cctacagcaa gtggcatatc 1100

 attgttctag gggttctctt gacggcagaa ctttgcctct agctcatttt 1150

 ccacagccta gattttccaa tcttgccaat ccagttgact tctgtcttct 1200

 catttccaag ccattgttct ctctctttca ctatctacat ggattatcct 1250

 tcattcaaac tgctttgtcc cggccgggtg cggtggctca tgcctgtagt 1300

 cctagcactt tgggaggccg aggcgggtgg atcacgaggt caggagatcg 1350

 agaccatcct ggctaacatg gtgaaacccc gtctctacta aaattaaaaa 1400

 aattagccgg gcgtggtggc aggcgcctgt ggtcccggct acttgggagg 1450

 ctgaggcggg agaatggcat gaacccggga ggtggagctt gcagtgggtg 1500

 gagatcgcgc cactgcactc cagcctgggc gacagagcga gactccgtct 1550

 gaaaaaaaaa acaaaaaaac tgctttgtcc tgtaggaatc ctgtgcgggt 1600

 tatgtgcacc tccctcaatc cttaccttga agctgaggtt tcccctcagc 1650

 tctcaagtac tcagtttgca ctgcaggtag tccctatttt aacgaaagtt 1700

 atacggtcca gctcagggaa tcctgaaaag ctgcccttgc ttccatggta 1750

 atcaaaaggc agttctcatg gaataaaagc tacctgaagc ctgagttggg 1800

 acctttggct ggggaaggtg gttgaggacg ttctctgatt agatgcttgg 1850

 catgaggttt gctactggaa ctgctagtgt agaatgtttc agccccctag 1900

 agttgtccct gtgatgtggc tacctccttt ctctgggatt tctcttaaag 1950

 tctggggagc ccctgcttct catttcctgg aatttatctt cccagtctcc 2000

 ctttctggct gaaaatttct agtatcttac agaacagcgg tgggatacac 2050

 tggagcacat catattacca ctaagtatgt ctaataaatg atgtcctctg 2100

 atttgacatt tcctaaatgt gaagctcctg attttataca attttgaaat 2150

 tagtaagctt gttagttttg tttgaaattc taggcattgg atacacttaa 2200

 catgagggct acatgtgcat caacatactc tggtttcctt ccctctgtat 2250

 cttttttttt tttgagatgg agtctcactg tctcctaggc tggagtgcag 2300

 tggtgtgatc atggctcact gcagccccaa ccttcagggc tcaggtgatc 2350

 ctcccgcctc agccacccaa gtggctggga ccgcaggtgc atgccaccat 2400

 gcctggctaa cttattttta tatattgtag agacggagtc tccctatgtt 2450

 gcctaggctg accttgagct cttgggctca ggtgatcctc ccgccttggc 2500

 ctcccaaagt gttgggatta taggcgtgag ccactgtgtc cagccttttc 2550

 ctctgtatct tgtatccatt ccccagagcg atactgtgta tccttgaaca 2600

 gacggtttct tgaagtcaga gtctatctcc tctgtcactt ctcccccttc 2650

 attatctaag actgaggttg tggtttatat gcttagagtt gaaagcatgg 2700

 ggtccaacgt gttctgtact ctgtagttcc ccagactctc cagggaaact 2750

 acttagctct caggtggttc ttttctgttt ttctcagagc aagttatcta 2800

 ataactgaag aggactctgc cctttggcct gttcctgact ttctaactcc 2850

 ttttgctgga ggaaggggag gttgaggggg gtgccctgtg gtgtgaaagc 2900

 cccacttgcc ctctcctcta tactttcttc caatgcagac gggagaaagt 2950

 atcataaatg tagtgactgt gggtcagggg agctctgaga ggccagcaca 3000

 ggaaaccaga aacaaaatga gtcagttcgt aggtggcgat cagaggcacc 3050

 ctgctgaggg tgcaaggcca caggtgatgc ctcctcagta ggcccaggag 3100

 catcaaaacg ggaacagtcc ctttcagcct tcaggagcct cccaaatgtc 3150

 acttagtgat gtcccattca cctgcttaaa ggccctgcat cctgccaggt 3200

 agttggtttg tccatagcat cctgagctct gcttgggtga gccagacaaa 3250

 aagaatgatt cctggccaga gtagtgatac cagggcccag acagaggcag 3300

 agagtccgga tagaagatcc tgtaagctgg ggtagggagc cgaggaggcc 3350

 atggagccag gggaatcatt gaagtgaggg acaatttctg gaggagggaa 3400

 actgagtaag gaaggcctgg ccaaggacca agaaggggac agtatcctga 3450

 tctatgaaag aagactcaag tggggattga cagagccaga ttgggtggag 3500

 tccaagcttt gggcaggtga gtgtccagga gatgagggct gagaatgggc 3550

 cttcagagcc cagccagaag gggaaagcac aaagctccac cctccttctt 3600

 cacatccctc catgctgctc aaatcccagg tcttcaggca ccatggagga 3650

 caaacgcaac atccagatca tcgagtggga acacctggac aagaagaagt 3700

 tctacgtgtt tggtgtggca atgacaatga tgatccgtgt cagtgtctac 3750

 ccattcaccc tcatccgcac ccggttgcaa gttcagaagg ggaagagcct 3800

 ctaccatggg accttcgatg ccttcatcaa gatcctgcga gcagatggta 3850

 tcactggcct ctaccgaggg ttcctggtca ataccttcac cctcatctct 3900

 ggccagtgtt atgtcaccac ttatgagctc acccggaagt ttgtagctga 3950

 ctacagccag agtaacacag tcaaatcact ggtggctggt ggctcagcct 4000

 cccttgtggc ccagagcatc acagtgccca ttgatgtagt ctcccagcac 4050

 ctgatgatgc aacgcaaggg tgagaaaatg ggccgctttc aggtgcgggg 4100

 gaacccagag ggacaagggg tagttgcctt tggccaaacc aaggacatca 4150

 tcaggcagat cctgcaggct gatggacttc gcggcttcta tcgaggctat 4200

 gtggcttcac tgcttaccta tatcccaaac agtgctgtct ggtggccctt 4250

 ctatcacttc tatgcagagc agctctccta cctgtgtcct aaggagtgcc 4300

 ctcacattgt ctttcaagct gtctcggggc ccctggctgc agccactgcc 4350

 tccatcctca ccaatcccat ggatgtcata cgaacccgtg tgcaggttga 4400

 gggcaagaac tccatcatcc tgaccttcag acagctgatg gcagaagaag 4450

 ggccttgggg cctcatgaag ggcctctcgg ccagaatcat ctcagccaca 4500

 ccttccacca ttgtcattgt ggtgggctat gagagcctca agaaactcag 4550

 cctccgacct gagctggtgg actcgagaca ctggtaacca gtggtgggga 4600

 gagaagcctg ctgttttcca cactaccgtg ggtcaggggc agagtggaga 4650

 ggacagcacc ctctccaggt gctcccacca cacacccagc cctgccctgg 4700

 gccaagtggc ctatctggga tagggataga gactttgaac tgctcttgct 4750

 gaagaggctc cacgcctgga tcccttgccc ccactattta aaattctctt 4800

 ctgagccggg ctccctcact cagtccctgt atttgatact ggcctaaaga 4850

 ccccaccccc caccctgcca gcccttcttc tggcttcccc ttccatctgt 4900

 gtccctgaga ccctgagaag agctgtacat agagcttgct tactaccact 4950

 ggttcttcct cttgggcttt cagcccagac tccaagcagc tgctatcaac 5000

 cctctctccc ttcatctctt agccttgctt atttttattt tgggaccgag 5050

 ctgcccacta gatgactctg cttttccctg catttggggc taaggtgcca 5100

 ggtacttatt tgcacaggga gcaggagcag caaaaaatct ctggttctcc 5150

 agagcactcg tcctctcttt ggaggggtta ttaggttggg agaaatgttg 5200

 atacttttgt tttgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg 5250

 tgtgtgtttt aacatctgtg aaccaggcta ttagtcctgc taaagcgcca 5300

 atcctgctgt cagagctcac ccccttccta agacaggtag aaaaatgtaa 5350

 tgtagctttt tccacaagcc agttccctgt cccttcagtc tcaggagccc 5400

 taggagagtc taagctgggg catcccctgg cccagaggac tcccgtggtg 5450

 ggcacagttc taagtggatc aggctgtctt gggtgcactg gacttggagc 5500

 actaccttga gaagtcaggt tgagaaagta gttgatctag aaggcaacaa 5550

 gtgggcatgt gttccccagc acattaccca ggccagcaga gccaaaccta 5600

 ggagagggca gtgggtagat tctctgcccc aggcagccat gacatacaca 5650

 taaatacccc aatcactcag acttacggca acaagtgttg tctcactatg 5700

 gtgatctcta agatccacat cactggatgc gtagtcatcc cagtcatggt 5750

 accctgtgga ggaatgctgg aagaacataa agagcagttc agaaagtcac 5800

 ccaataccag gaccactgca tttaccagcc tgatactgcc aagattatct 5850

 gatgctctcc tcaggagcta ggagaggagt gctccttcct ccctaccgct 5900

 actctcccca agcctgtgtt gcaggtagag aggtgcagca aatagagaag 5950

 gcatgtcaaa ccctgcattt ctacctgaga gtgtgacctg gatgatcctc 6000

 caaaccctat tggtcccacc ccctgggaaa ggccatggtg ccagtttgaa 6050

 aggtgctagc tacctgaagc cttgatattt cttcatggct gccgcacatt 6100

 cttccacctt ggccagaaca ggttctgaaa accgcttctc taccttcacc 6150

 accaccactg cccatcttga tctctttgag ggttttccca tttcacttga 6200

 tcttattttt gtttatccct tcctgcactt tgtcaagaga gtcctccagt 6250

 ttctatccag gaatgttcac atccaaaggg ttggacccac ggatcattct 6300

 gaatcttcct gcccctcctc actgcttaac cctgagaacc acaaatataa 6350

 tggaagcagt tccccccacc ctcaccccat ctctttaagc tcatcctagc 6400

 aagacctcta gagaccctag agactcgact ttagccttcc ccgccatggc 6450

 acagtgggga aggtgtcaat ggggagtgtc acggacagga ggtaggatcc 6500

 tgccgctcgc gtcttagtgt ttctccctca agactttcct tctgttttgt 6550

 tgtcttgtgc agtattttac agcccctctt gtgtttttct ttatttctcg 6600

 tacacacacg cagttttaag ggtgatgtgt gtataattaa aaggaccctt 6650

 ggcccatact ttcctaattc tttagggact gggattgggt ttgactgaaa 6700

 tatgttttgg tggggatggg acggtggact tccattctcc ctaaactgga 6750

 gttttggtcg gtaatcaaaa ctaaaagaaa cctctgggag actggaaacc 6800

 tgattggagc actgaggaac aagggaatga aaaggcagac tctctgaacg 6850

 tttgatgaaa tggactcttg tgaaaattaa cagtgaatat tcactgttgc 6900

 actgtacgaa gtctctgaaa tgtaattaaa agtttttatt gagcccccg 6949

<210> 2656
<211> 368
<212> PRT
<213> Homo sapien

<400> 2656
 Gln Ser Gln Ile Gly Trp Ser Pro Ser Phe Gly Gln Val Ser Val
   1               5                  10                  15

 Gln Glu Met Arg Ala Glu Asn Gly Pro Ser Glu Pro Ser Gln Lys
                  20                  25                  30

 Gly Lys Ala Gln Ser Ser Thr Leu Leu Leu His Ile Pro Pro Cys
                  35                  40                  45

 Cys Ser Asn Pro Arg Ser Ser Gly Thr Met Glu Asp Lys Arg Asn
                  50                  55                  60

 Ile Gln Ile Ile Glu Trp Glu His Leu Asp Lys Lys Lys Phe Tyr
                  65                  70                  75

 Val Phe Gly Val Ala Met Thr Met Met Ile Arg Val Ser Val Tyr
                  80                  85                  90

 Pro Phe Thr Leu Ile Arg Thr Arg Leu Gln Val Gln Lys Gly Lys
                  95                 100                 105

 Ser Leu Tyr His Gly Thr Phe Asp Ala Phe Ile Lys Ile Leu Arg
                 110                 115                 120

 Ala Asp Gly Ile Thr Gly Leu Tyr Arg Gly Phe Leu Val Asn Thr
                 125                 130                 135

 Phe Thr Leu Ile Ser Gly Gln Cys Tyr Val Thr Thr Tyr Glu Leu
                 140                 145                 150

 Thr Arg Lys Phe Val Ala Asp Tyr Ser Gln Ser Asn Thr Val Lys
                 155                 160                 165

 Ser Leu Val Ala Gly Gly Ser Ala Ser Leu Val Ala Gln Ser Ile
                 170                 175                 180

 Thr Val Pro Ile Asp Val Val Ser Gln His Leu Met Met Gln Arg
                 185                 190                 195

 Lys Gly Glu Lys Met Gly Arg Phe Gln Val Arg Gly Asn Pro Glu
                 200                 205                 210

 Gly Gln Gly Val Val Ala Phe Gly Gln Thr Lys Asp Ile Ile Arg
                 215                 220                 225

 Gln Ile Leu Gln Ala Asp Gly Leu Arg Gly Phe Tyr Arg Gly Tyr
                 230                 235                 240

 Val Ala Ser Leu Leu Thr Tyr Ile Pro Asn Ser Ala Val Trp Trp
                 245                 250                 255

 Pro Phe Tyr His Phe Tyr Ala Glu Gln Leu Ser Tyr Leu Cys Pro
                 260                 265                 270

 Lys Glu Cys Pro His Ile Val Phe Gln Ala Val Ser Gly Pro Leu
                 275                 280                 285

 Ala Ala Ala Thr Ala Ser Ile Leu Thr Asn Pro Met Asp Val Ile
                 290                 295                 300

 Arg Thr Arg Val Gln Val Glu Gly Lys Asn Ser Ile Ile Leu Thr
                 305                 310                 315

 Phe Arg Gln Leu Met Ala Glu Glu Gly Pro Trp Gly Leu Met Lys
                 320                 325                 330

 Gly Leu Ser Ala Arg Ile Ile Ser Ala Thr Pro Ser Thr Ile Val
                 335                 340                 345

 Ile Val Val Gly Tyr Glu Ser Leu Lys Lys Leu Ser Leu Arg Pro
                 350                 355                 360

 Glu Leu Val Asp Ser Arg His Trp
                 365

<210> 2657
<211> 1165
<212> DNA
<213> Homo sapien

<400> 2657
 gttctcatac aagatttatt ccccagcaca cccctcccct cctcagttca 50

 cagtggagac tatggagatt cagggcagga tccctcaggt acaagaaaca 100

 ccttccgaag attttgctct ccttccttcc ctccctcttg ccaactccca 150

 aggcctgaag cgcacactca tgcaaacaca cgaaatcccc ctccttcccc 200

 acacctcctg tctttccaca tcagagctct gaacttgaga ggtgtcaaaa 250

 gtctgtttga gaagcctaaa gtggggagat gccattaccc ctgaccaccc 300

 cactatgagt gactatgaga cacctaactc ttccctcttc tgtcaaccat 350

 tttcactccc tggcctctgt accttctcca tcaaccaaga gcaaacatgt 400

 cagcacaccc ccacctgcag tacatgaaaa caggctctgt ccaacatccc 450

 tcacccaagt acaggggtgt tgggggagtg gcccctgagg atcagcaaag 500

 ggttaatgca gaaggaaaga ggacagaagc gtttggcttg agctctgctt 550

 ggggaggcag aggctataga ctggcacagg tttagaatca agtaccatgt 600

 ttaggtttct gtctcacatc acatgatttc actaggggct gcagaacaga 650

 tacccctcag aggggtctct gctgattaca gccacattct tactattggc 700

 tcatccttaa aggaggcccc accaagttgg gaagcagttg aaaataaaag 750

 ctgtaaaggg agctgaacag gaagtaagaa taggtggtgc aagagattat 800

 ggcccctggg atgaatgaca tggagccatt tgtaaagtgc tactgtatca 850

 tcccccatga attattgctt ctccaaagga ggagcagagg aaggaacagg 900

 aacatagaaa tgagtatggt attgctttgc tcactgctga ggctgatggc 950

 cagatggacc caggggttat cagaaaccga agattaacta cacagctcca 1000

 gaagactcag acctcaaaat acagaggtgc tcactaatcc tcccagccag 1050

 ctgatccccc tgggccaagg taatgtagaa gaggcccatc cccacatcat 1100

 attcacattt tttaaatttc acaagcaata ctttggacca ctggggttca 1150

 ggccccaaga aatga 1165

<210> 2658
<211> 1296
<212> DNA
<213> Homo sapien

<400> 2658
 ctgggtcctg gcctttgggc atcatccagc gccatcggcc tggcgcttca 50

 gccaacgcgg gagtggatgg gccccttctt cttcgcagac agcgttcggc 100

 cgctgcccgg gctctaggcg cggccggacg gcccagtctg gagggttcgg 150

 ggcggaggcc cgggggggtg cgcgcgcccg gggtccggcc tctcactcgc 200

 tcccctctcg tccgcagccg cagggccgta ggcagccatg gcgcccagcc 250

 ggaatggcat ggtcttgaag ccccacttcc acaaggactg gcagcggcgc 300

 gtggccacgt ggttcaacca gccggcccgt aagatccgca gacgtaaggc 350

 ccggcaagcc aaggcgcgcc gcatcgcccc gcgccccgcg tcgggtccca 400

 tccggcccat cgtgcgctgc cccacggttc ggtaccacac gaaggtgcgc 450

 gccggccgcg gcttcagcct ggaggagctc agggtggccg gcattcacaa 500

 gaaggtggcc cggaccatcg gcatttctgt ggatccgagg aggcggaaca 550

 agtccacgga gtccctgcag gccaacgtgc agcggctgaa ggagtaccgc 600

 tccaaactca tcctcttccc caggaagccc tcggccccca agaagggaga 650

 cagttctgct gaagaactga aactggccac ccagctgacc ggaccggtca 700

 tgcccgtccg gaacgtctat aagaaggaga aagctcgagt catcactgag 750

 gaagagaaga atttcaaagc cttcgctagt ctccgtatgg cccgtgccaa 800

 cgcccggctc ttcggcatac gggcaaaaag agccaaggaa gccgcagaac 850

 aggatgttga aaagaaaaaa taaagccctc ctggggactt ggaatcagtc 900

 ggcagtcatg ctgggtctcc acgtggtgtg tttcgtggga acaactgggc 950

 ctgggatggg gcttcactgc tgtgacttcc tcctgccagg ggatttgggg 1000

 ctttcttgaa agacagtcca agccctggat aatgctttac tttctgtgtt 1050

 gaagcactgt tggttgtttg gttagtgact gatgtaaaac ggttttcttg 1100

 tggggaggtt acagaggctg acttcagagt ggacttgtgt tttttctttt 1150

 taaagaggca aggttgggct ggtgctcaca gctgtaatcc cagcactttg 1200

 aggttggctg ggagttcaag accagcctgg ccaacatgtc agaactacta 1250

 aaaataaaga aatcagccat gaaaaaaaaa aaaaaaaaaa aaaaaa 1296

<210> 2659
<211> 211
<212> PRT
<213> Homo sapien

<400> 2659
 Met Ala Pro Ser Arg Asn Gly Met Val Leu Lys Pro His Phe His
   1               5                  10                  15

 Lys Asp Trp Gln Arg Arg Val Ala Thr Trp Phe Asn Gln Pro Ala
                  20                  25                  30

 Arg Lys Ile Arg Arg Arg Lys Ala Arg Gln Ala Lys Ala Arg Arg
                  35                  40                  45

 Ile Ala Pro Arg Pro Ala Ser Gly Pro Ile Arg Pro Ile Val Arg
                  50                  55                  60

 Cys Pro Thr Val Arg Tyr His Thr Lys Val Arg Ala Gly Arg Gly
                  65                  70                  75

 Phe Ser Leu Glu Glu Leu Arg Val Ala Gly Ile His Lys Lys Val
                  80                  85                  90

 Ala Arg Thr Ile Gly Ile Ser Val Asp Pro Arg Arg Arg Asn Lys
                  95                 100                 105

 Ser Thr Glu Ser Leu Gln Ala Asn Val Gln Arg Leu Lys Glu Tyr
                 110                 115                 120

 Arg Ser Lys Leu Ile Leu Phe Pro Arg Lys Pro Ser Ala Pro Lys
                 125                 130                 135

 Lys Gly Asp Ser Ser Ala Glu Glu Leu Lys Leu Ala Thr Gln Leu
                 140                 145                 150

 Thr Gly Pro Val Met Pro Val Arg Asn Val Tyr Lys Lys Glu Lys
                 155                 160                 165

 Ala Arg Val Ile Thr Glu Glu Glu Lys Asn Phe Lys Ala Phe Ala
                 170                 175                 180

 Ser Leu Arg Met Ala Arg Ala Asn Ala Arg Leu Phe Gly Ile Arg
                 185                 190                 195

 Ala Lys Arg Ala Lys Glu Ala Ala Glu Gln Asp Val Glu Lys Lys
                 200                 205                 210

 Lys


<210> 2660
<211> 879
<212> DNA
<213> Homo sapien

<400> 2660
 ggccgggcgt catgggcggc ctcttctggc gctccgcgct gcgggggctg 50

 cgctgcggcc cgcgggcccc gggcccgagc ctgctagtgc gccacggctc 100

 gggagggccc tcctggaccc gggagcggac cctggtggcg gtgaagcccg 150

 atggcgtgca acggcggctc gttggggacg tgatccagcg ctttgagagg 200

 cggggcttca cgctggtggg gatgaagatg ctgcaggcac cagagagcgt 250

 ccttgccgag cactaccagg acctgcggag gaagcccttc taccctgccc 300

 tcatccgcta catgagctct gggcctgtgg tggccatggt ctgggaaggg 350

 tacaatgtcg tccgcgcctc aagggccatg attggacaca ccgactcggc 400

 tgaggctgcc ccaggaacca taaggggtga cttcagcgtc cacatcagca 450

 ggaatgtcat ccacgccagc gactccgtgg agggggccca gcgggagatc 500

 cagctgtggt tccagagcag tgagctggtg agctgggcag acgggggcca 550

 gcacagcagc atccacccag cctgaggctc aagctgccct taccacccca 600

 tcccccacgc aggaccaact acctccgtca gcaagaaccc aagcccacat 650

 ccaaacctgc ctgtcccaaa ccacttactt ccctgttcac ctctgcccca 700

 ccccagccca gaggagtttg agccaccaac ttcagtgcct ttctgtaccc 750

 caagccagca caagattgga ccaatccttt ttgcaccaaa gtgccggaca 800

 acctttgtgg tggggggggg tcttcacatt atcataacct ctcctctaaa 850

 ggggaggcat taaaattcac tgtgcccag 879

<210> 2661
<211> 187
<212> PRT
<213> Homo sapien

<400> 2661
 Met Gly Gly Leu Phe Trp Arg Ser Ala Leu Arg Gly Leu Arg Cys
   1               5                  10                  15

 Gly Pro Arg Ala Pro Gly Pro Ser Leu Leu Val Arg His Gly Ser
                  20                  25                  30

 Gly Gly Pro Ser Trp Thr Arg Glu Arg Thr Leu Val Ala Val Lys
                  35                  40                  45

 Pro Asp Gly Val Gln Arg Arg Leu Val Gly Asp Val Ile Gln Arg
                  50                  55                  60

 Phe Glu Arg Arg Gly Phe Thr Leu Val Gly Met Lys Met Leu Gln
                  65                  70                  75

 Ala Pro Glu Ser Val Leu Ala Glu His Tyr Gln Asp Leu Arg Arg
                  80                  85                  90

 Lys Pro Phe Tyr Pro Ala Leu Ile Arg Tyr Met Ser Ser Gly Pro
                  95                 100                 105

 Val Val Ala Met Val Trp Glu Gly Tyr Asn Val Val Arg Ala Ser
                 110                 115                 120

 Arg Ala Met Ile Gly His Thr Asp Ser Ala Glu Ala Ala Pro Gly
                 125                 130                 135

 Thr Ile Arg Gly Asp Phe Ser Val His Ile Ser Arg Asn Val Ile
                 140                 145                 150

 His Ala Ser Asp Ser Val Glu Gly Ala Gln Arg Glu Ile Gln Leu
                 155                 160                 165

 Trp Phe Gln Ser Ser Glu Leu Val Ser Trp Ala Asp Gly Gly Gln
                 170                 175                 180

 His Ser Ser Ile His Pro Ala
                 185

<210> 2662
<211> 4019
<212> DNA
<213> Homo sapien

<400> 2662
 cccgggtatc aaaagaagga tcggctccgc ccccgggctc cccgggggag 50

 ttgatagaag ggtccttccc accctttgcc gtccccactc ctgtgcctac 100

 gacccaggag cgtgtcagcc aaagcatgga gaatcaagag aaggcgagta 150

 tcgcgggcca catgttcgac gtagtcgtga tcggaggtgg catttcagga 200

 ctatctgctg ccaaactctt gactgaatat ggcgttagtg ttttggtttt 250

 agaagctcgg gacagggttg gaggaagaac atatactata aggaatgagc 300

 atgttgatta cgtagatgtt ggtggagctt atgtgggacc aacccaaaac 350

 agaatcttac gcttgtctaa ggagctgggc atagagactt acaaagtgaa 400

 tgtcagtgag cgtctcgttc aatatgtcaa ggggaaaaca tatccatttc 450

 ggggcgcctt tccaccagta tggaatccca ttgcatattt ggattacaat 500

 aatctgtgga ggacaataga taacatgggg aaggagattc caactgatgc 550

 accctgggag gctcaacatg ctgacaaatg ggacaaaatg accatgaaag 600

 agctcattga caaaatctgc tggacaaaga ctgctaggcg gtttgcttat 650

 ctttttgtga atatcaatgt gacctctgag cctcacgaag tgtctgccct 700

 gtggttcttg tggtatgtga agcagtgcgg gggcaccact cggatattct 750

 ctgtcaccaa tggtggccag gaacggaagt ttgtaggtgg atctggtcaa 800

 gtgagcgaac ggataatgga cctcctcgga gaccaagtga agctgaacca 850

 tcctgtcact cacgttgacc agtcaagtga caacatcatc atagagacgc 900

 tgaaccatga acattatgag tgcaaatacg taattaatgc gatccctccg 950

 accttgactg ccaagattca cttcagacca gagcttccag cagagagaaa 1000

 ccagttaatt cagcgtcttc caatgggagc tgtcattaag tgcatgatgt 1050

 attacaagga ggccttctgg aagaagaagg attactgtgg ctgcatgatc 1100

 attgaagatg aagatgctcc aatttcaata accttggatg acaccaagcc 1150

 agatgggtca ctgcctgcca tcatgggctt cattcttgcc cggaaagctg 1200

 atcgacttgc taagctacat aaggaaataa ggaagaagaa aatctgtgag 1250

 ctctatgcca aagtgctggg atcccaagaa gctttacatc cagtgcatta 1300

 tgaagagaag aactggtgtg aggagcagta ctctgggggc tgctacacgg 1350

 cctacttccc tcctgggatc atgactcaat atggaagggt gattcgtcaa 1400

 cccgtgggca ggattttctt tgcgggcaca gagactgcca caaagtggag 1450

 cggctacatg gaaggggcag ttgaggctgg agaacgagca gctagggagg 1500

 tcttaaatgg tctcgggaag gtgaccgaga aagacatctg ggtacaagaa 1550

 cctgaatcaa aggacgttcc agcggtagaa atcacccaca ccttctggga 1600

 aaggaacctg ccctctgttt ctggcctgct gaagatcatt ggattttcca 1650

 catcagtaac tgccctgggg tttgtgctgt acaaatacaa gctcctgcca 1700

 cggtcttgaa gttctgttct tatgctctct gctcactggt tttcaatacc 1750

 accaagagga aaatattgac aagtttaaag gctgtgtcat tgggccatgt 1800

 ttaagtgtac tggatttaac tacctttggc ttaattccaa tcattgttaa 1850

 agtaaaaaca attcaaagaa tcacctaatt aatttcagta agatcaagct 1900

 ccatcttatt tgtcagtgta gatcaactca tgttaattga tagaataaag 1950

 ccttgtgatc actttctgaa attcacaaag ttaaacgtga tgtgctcatc 2000

 agaaacaatt tctgtgtcct gtttttattc ccttcaatgc aaaatacatg 2050

 atgatttcag aaacaaagca tttgactttc tgtctgtgga ggtggagtag 2100

 gtgaaggccc agcctgtaac tgtccttttt cttcccttag gcaatggtga 2150

 actgtcatta cagagcctag aggctcacag cctcctggag gaagcagcct 2200

 ccactttgga tcaggaaata gtaaaggaaa gcagtgttgg gggtagcggc 2250

 atgcagaccc tcagaccaga atggggacat cttgtggtct gctgcctcag 2300

 gaatctcctg accacttgta gtccctccga cttctctaga catctagtct 2350

 cagtgctagc ttatttgtat ttttcctctt tcacttctta tggaggagag 2400

 tgtttaactg agttagaatg ttgaaactga cttgctgtga cttatgtgca 2450

 gctttccagt tgagcagagg aaaatagtgg caggactgtc ccccaggagg 2500

 actccctgct tagctctgtg ggagaccaac tacgactggc atcttctctt 2550

 ccccctggaa ggcagctaga caccaatgga tccttgtcag ttgtaacatt 2600

 ctatttcaac ttcaggaaag cagcagtttt cttttaattt ttcctatgac 2650

 cataaaatta gacatacctc tcaacttaca tatgtcttca acatggttac 2700

 ctctgcataa atattagcaa agcatgccaa tttctcttaa gtactgaaat 2750

 acatatgata aatttgactg ttatttgttg agactatcaa acagaaaaga 2800

 aattagggct ctaatttcct taaagcaagc tcacttgctt tagttgttaa 2850

 gttttataaa agacatgaaa ttgagtcatt ttatatatga aaactaagtt 2900

 ctctatctta ggagtaatgt cggcccacaa gggtgcccac ctcttgtttt 2950

 ccccttttaa aaactcagat ttttaaaagc cctttccaaa ggtttcaact 3000

 gtaaaatact tctttttaca atgtatcaac atatttttat ttaaggggaa 3050

 ttaacaattg ccagggaaac cagccaaccc aagtttatta tatcattaac 3100

 cttatcataa attcaaacct aagttgctgg accctggtgt gaggacataa 3150

 atcttccaaa gttttgccta tcctaagagc tgcatttttc tactgctctt 3200

 taccttgcat tttagctaat ttaggagttt tgagaatgta ttggatacgc 3250

 tccagtacat aaggagttgc cgcatattat atcagactgc tttgagaaat 3300

 ctcatcccta gtctattgca gttgtttcta ttagcttact gattaactca 3350

 gtcctgacac accttttggg aaatgctgat ttaaacttct taactggcaa 3400

 cagttggaac agtaatcagt ttgctaacat atttaaagtc ttgaatgttg 3450

 aagaactcat gtgatttacc cttttcaact ttttggaaaa cgatttaatt 3500

 tattctaatt agattaaccc tattaatcta tggattgggt atcaaaatga 3550

 atgccagtcc agatgtgcct agacacgaaa ttggagctga ggactctcac 3600

 gatatgcaag ttcatccaac gtgaagatac cataagcttt ttctctgaac 3650

 cagagaaatg aaagtcagtt taagaggctg atagatcttg gccctgttaa 3700

 ggcatccact tcacagttct gaaggctgag tcagccccac tccacagtta 3750

 ggccaagaat tagattttaa aacttcatct gtctgtccca gttaactgtt 3800

 aaataaggcc tcatcctcca ctgaagagta tggattgaag gattgtgaac 3850

 tatgtttagt gtgattgtga acttggtgcc taatgttcca tgtctgaagt 3900

 ttgccccagt gctacacgtt ggagtatacc tatgtgtgtg ctttgccact 3950

 gaagtaagat tttgcctgta tggtactgtt ttgtttgtta ataaagtgca 4000

 ctgccacccc caatgcaaa 4019

<210> 2663
<211> 568
<212> PRT
<213> Homo sapien

<400> 2663
 Arg Val Ser Lys Glu Gly Ser Ala Pro Pro Pro Gly Ser Pro Gly
   1               5                  10                  15

 Glu Leu Ile Glu Gly Ser Phe Pro Pro Phe Ala Val Pro Thr Pro
                  20                  25                  30

 Val Pro Thr Thr Gln Glu Arg Val Ser Gln Ser Met Glu Asn Gln
                  35                  40                  45

 Glu Lys Ala Ser Ile Ala Gly His Met Phe Asp Val Val Val Ile
                  50                  55                  60

 Gly Gly Gly Ile Ser Gly Leu Ser Ala Ala Lys Leu Leu Thr Glu
                  65                  70                  75

 Tyr Gly Val Ser Val Leu Val Leu Glu Ala Arg Asp Arg Val Gly
                  80                  85                  90

 Gly Arg Thr Tyr Thr Ile Arg Asn Glu His Val Asp Tyr Val Asp
                  95                 100                 105

 Val Gly Gly Ala Tyr Val Gly Pro Thr Gln Asn Arg Ile Leu Arg
                 110                 115                 120

 Leu Ser Lys Glu Leu Gly Ile Glu Thr Tyr Lys Val Asn Val Ser
                 125                 130                 135

 Glu Arg Leu Val Gln Tyr Val Lys Gly Lys Thr Tyr Pro Phe Arg
                 140                 145                 150

 Gly Ala Phe Pro Pro Val Trp Asn Pro Ile Ala Tyr Leu Asp Tyr
                 155                 160                 165

 Asn Asn Leu Trp Arg Thr Ile Asp Asn Met Gly Lys Glu Ile Pro
                 170                 175                 180

 Thr Asp Ala Pro Trp Glu Ala Gln His Ala Asp Lys Trp Asp Lys
                 185                 190                 195

 Met Thr Met Lys Glu Leu Ile Asp Lys Ile Cys Trp Thr Lys Thr
                 200                 205                 210

 Ala Arg Arg Phe Ala Tyr Leu Phe Val Asn Ile Asn Val Thr Ser
                 215                 220                 225

 Glu Pro His Glu Val Ser Ala Leu Trp Phe Leu Trp Tyr Val Lys
                 230                 235                 240

 Gln Cys Gly Gly Thr Thr Arg Ile Phe Ser Val Thr Asn Gly Gly
                 245                 250                 255

 Gln Glu Arg Lys Phe Val Gly Gly Ser Gly Gln Val Ser Glu Arg
                 260                 265                 270

 Ile Met Asp Leu Leu Gly Asp Gln Val Lys Leu Asn His Pro Val
                 275                 280                 285

 Thr His Val Asp Gln Ser Ser Asp Asn Ile Ile Ile Glu Thr Leu
                 290                 295                 300

 Asn His Glu His Tyr Glu Cys Lys Tyr Val Ile Asn Ala Ile Pro
                 305                 310                 315

 Pro Thr Leu Thr Ala Lys Ile His Phe Arg Pro Glu Leu Pro Ala
                 320                 325                 330

 Glu Arg Asn Gln Leu Ile Gln Arg Leu Pro Met Gly Ala Val Ile
                 335                 340                 345

 Lys Cys Met Met Tyr Tyr Lys Glu Ala Phe Trp Lys Lys Lys Asp
                 350                 355                 360

 Tyr Cys Gly Cys Met Ile Ile Glu Asp Glu Asp Ala Pro Ile Ser
                 365                 370                 375

 Ile Thr Leu Asp Asp Thr Lys Pro Asp Gly Ser Leu Pro Ala Ile
                 380                 385                 390

 Met Gly Phe Ile Leu Ala Arg Lys Ala Asp Arg Leu Ala Lys Leu
                 395                 400                 405

 His Lys Glu Ile Arg Lys Lys Lys Ile Cys Glu Leu Tyr Ala Lys
                 410                 415                 420

 Val Leu Gly Ser Gln Glu Ala Leu His Pro Val His Tyr Glu Glu
                 425                 430                 435

 Lys Asn Trp Cys Glu Glu Gln Tyr Ser Gly Gly Cys Tyr Thr Ala
                 440                 445                 450

 Tyr Phe Pro Pro Gly Ile Met Thr Gln Tyr Gly Arg Val Ile Arg
                 455                 460                 465

 Gln Pro Val Gly Arg Ile Phe Phe Ala Gly Thr Glu Thr Ala Thr
                 470                 475                 480

 Lys Trp Ser Gly Tyr Met Glu Gly Ala Val Glu Ala Gly Glu Arg
                 485                 490                 495

 Ala Ala Arg Glu Val Leu Asn Gly Leu Gly Lys Val Thr Glu Lys
                 500                 505                 510

 Asp Ile Trp Val Gln Glu Pro Glu Ser Lys Asp Val Pro Ala Val
                 515                 520                 525

 Glu Ile Thr His Thr Phe Trp Glu Arg Asn Leu Pro Ser Val Ser
                 530                 535                 540

 Gly Leu Leu Lys Ile Ile Gly Phe Ser Thr Ser Val Thr Ala Leu
                 545                 550                 555

 Gly Phe Val Leu Tyr Lys Tyr Lys Leu Leu Pro Arg Ser
                 560                 565

<210> 2664
<211> 6113
<212> DNA
<213> Homo sapien

<400> 2664
 ccccggtgca ccgtgctagc ccccagccag ggcgttgggg agggcggtgg 50

 ccatggccag tcacgtggac ctgctgacgg agctgcagct gctggagaag 100

 gtgcccacgc tggagcggct gcgggctgcc cagaagcgcc gggcccagca 150

 gctgaagaaa tgggcacagt acgagcagga cttgcagcac cgcaagcgaa 200

 agcatgagcg gaagcgcagc acgggcggtc gccgcaagaa agtgtccttc 250

 gaggccagcg tggccctgct ggaggcctcg ctgaggaacg acgccgagga 300

 agtacgctac ttcctgaaga ataaggtcag ccctgatttg tgcaatgagg 350

 acggactcac agccctacac cagtgctgca tcgacaactt tgaggaaatt 400

 gtgaagctgc tcctctccca tggtgccaat gtgaacgcca aggacaacga 450

 gctgtggaca cctctccatg ctgcagccac ctgcggccac atcaacctgg 500

 tgaagatcct cgttcagtat ggggccgact tgcttgctgt caactcggat 550

 gggaacatgc catatgacct ctgcgaggat gaacccaccc tggatgtcat 600

 cgagacctgc atggcatacc agggcatcac ccaagagaaa atcaacgaga 650

 tgcgggtggc tcctgagcag cagatgattg cggacatcca ctgcatgatc 700

 gcagcgggcc aggacctgga ctggatagat gcccagggtg ccacactgct 750

 gcacatagct ggagccaatg gatacctgcg ggcagctgag ctcctcctgg 800

 atcatggagt gcgtgtggat gtgaaggact gggatggctg ggagcccctg 850

 catgcagctg ccttctgggg acagatgcag atggcagagc tattggtgtc 900

 ccatggagct agtctcagtg caaggacatc catggatgag atgccaatag 950

 acctgtgcga ggaggaagag ttcaaggtcc tgctgctgga gctaaaacac 1000

 aagcatgatg tgatcatgaa gtcacagctg aggcacaagt catccttgag 1050

 ccggaggacc tccagcgcag gcagccgtgg gaaggtggtg cggcgagcca 1100

 gcctgtcgga caggaccaac ctgtatagga aggagtatga gggagaggcc 1150

 atcctgtggc agcggagtgc agctgaggat cagcggacct ccacctacaa 1200

 cggggacatc agggagacca ggacagacca agagaataag gaccctaacc 1250

 ccaggctgga gaagcccgtg ctactctccg aatttcctac caagatccca 1300

 cgaggtgaac tggacatgcc tgttgagaat ggcctccggg ctccggtcag 1350

 tgcctaccag tatgcgctgg ccaacgggga tgtctggaag gtgcatgagg 1400

 tgcctgacta cagcatggcc tatggcaacc ctggcgtggc cgacgccacc 1450

 ccgccctgga gcagctacaa ggaacagagc cctcagacgc ttctggagct 1500

 gaagcggcag cgggctgcag ccaagctgct cagccacccc ttccttagca 1550

 cacacctggg cagcagcatg gccaggacgg gcgagagtag cagtgaaggc 1600

 aaggctccct tgatcggagg cagaacttca ccgtacagca gcaatgggac 1650

 ctcggtatat tacacggtca ccagcggaga tcccccactc ttaaagttca 1700

 aggcccccat agaggagatg gaggagaagg tgcatggctg ttgccgtatc 1750

 tcctagtctc cgtgtgatgg aggagggaga tgcctgggga ggggctcctg 1800

 gaatccaggc cagcccaaca accctggctg gggaggtgtc agggcagctg 1850

 gggagaggtg ggctctgctt ttcagaggaa ctcagacccc agccctcagc 1900

 tggctgccca tagcatccca tgtcccacgt cccgtggttc tgcttcctgc 1950

 tgcatcgtct gccatctgac acaaggcctg tcgtggcctc ctggttcact 2000

 ctgctgtctg atcttgggag ggtgggcttg agatcccagc tctattcttg 2050

 gtataaaggc ttctccggat cagtacatgc atgtcacatt aacacacaca 2100

 cacacacaca tatacacaca cacacaagct cgatcagtgt gtgtaggaat 2150

 gacatacctg ggctcagggg aagcaagggg gcttagaatt tgtggggtat 2200

 tcccaaaagg atggaagtta agactcagag tctcattacc actgccaatg 2250

 tggttttagc aggggagggg acctgctaag ctgagaccca tagtcctgct 2300

 cagagttatc ccaaagtctg agccaccagc cacacctgac aggggtgaga 2350

 agtcctcgct gtgttcagag ggagccagga atctacatgg gtagatgaga 2400

 tagacacaga cctgctcccc gcagccttgt tgagagccac acttctgccc 2450

 atgccaggag ccagctgtgt gaccatccag gggtggaggg ggaaaaccag 2500

 gcaatttcgt tcctggaatc aaccaaatca tgttttcctc ttggatggaa 2550

 gtgtcaaagg cagaagggtg tgggaggggg acaaggtcag tatttaccaa 2600

 agtgtatctg attttaaaaa ttcctttagt ctgtaaaact cctagaggga 2650

 gggaggtaac tgaattcact tctttttgtg gatcgtatca aggtcactgg 2700

 gttttactgg ctggtgctgg gaaaatgaag ctaagtgagg agcttccatt 2750

 ggaatgcttt tccagggaga gaggccagtt aatttaaaaa aaacagtcgc 2800

 tagttaacag cgacagagcc cagcaccctg gggtctttgt gaatatccag 2850

 actgtttcag cccagcccat ctcagccaac cctccttaga ctgagctgtc 2900

 agagcaagca attaggggcc agcctgcctc cacctcccac ccccttccac 2950

 ctccatcagt catgtgtgca gagtcagtgc tcgggatccc gggcccagct 3000

 tttgcctttt tggggatgct tggtgagaca gatttgccag tcagcccttt 3050

 tgagttcccg cctcacccag gggctcccag cctgcacttg caggagtggt 3100

 gatgccccaa gtctgcgaat ccagggtgca cgtggtcaat atcccctcct 3150

 gcattcagga gagccatggt agggctggag ttgggtcttg cccagccctg 3200

 cagtttcata gtcccagcct tcctggtgct ggggagggag gactgtgaat 3250

 ggctgttctc ccctcactgc tgagtctccc aggaccccct ttggagatgc 3300

 ccatggcatg ggcactgccc acaggctcag ccagaacctc ttggtgtacc 3350

 cgataagctg caggttatcc cttgctctgt gcgcctttta tttgtcctta 3400

 aactacctcc ttagagctct gaaggggtct cctagttcca gattttaatt 3450

 tggggaacag atctgggttc tttttaaccc tcttctttct cagtctatga 3500

 gaaacttgcc ctgaggggca cctgggctag gggcttggga ctggaagacc 3550

 atccccgcct tgtgccacaa ctttggtcat gggatctgct ctttgtcatt 3600

 cttagccccc tactgtggcc cccatagccc cataacccag agagggagct 3650

 ggacttcagg gagcctgagt gatgctttcc caggagcagg gcagctggct 3700

 ggaccagaaa gtagagggcc catgggagtg actgcaccct tggtggctgc 3750

 tggaaaggga gaggttctca gcatcaggcc acctccaccc caatgccagg 3800

 atagatgtat tctagagtag gggtggaggc ggcccaggag gctgaagaca 3850

 ggtgcacaga tgcttcccac gaccttgcca tttggggtgg gctcttcaac 3900

 atctcaggct gtggctggaa caggacagga tgatctaaaa cacacgtacc 3950

 attggctgta aaacagtatg agcccagact gacgctgaaa tccctcatga 4000

 gccaacctta gctacaaggt agggagttct gagggaagcc gcgtgctcct 4050

 caggagagag ctgtttaggt tttccgatct ttttgctcag gggccaaaca 4100

 ctgaaggcac gtactgccca acccactgag cgcctgaggc cattccctcc 4150

 ttttccgcat gcctcctgcc tcctgggcta ttcctctcca cccagaaggc 4200

 tgggaatccc agctgattcc ctgacaggag ccgacttcac acacaggtga 4250

 ctctcaggca ttggctcatg ttttcagcca gggataaacc atcccttctt 4300

 ggggctttaa gtccctgggg agctttccct gtaggtctcc tgggtgttga 4350

 gagacaagtt ggagaccaac ctccaatgaa tgagccgcgg tcattcatta 4400

 attcactcac gtaatttact gagtagctgc aacatgccag cctctacgtt 4450

 aggttctgcg gataaaggag gaataagaca gagtcaggag aactgttcct 4500

 tgtggtttcc gtcccttggg gaccacaggc atcagcagtc ccattcaagt 4550

 cacctgaggc aaagtgtctg catcttcgtc cagcgaccct ttgcttttcg 4600

 gctcctagaa tccttagagt ctgaattcct ttagctggga acagctgtca 4650

 tggtcacccc tggataacat ttgccaccaa gtatagatgc tggatcttgg 4700

 gttccaggca gacatcatcc aggtccatct ggaactttca gtgatagctg 4750

 ccttcagcca gcatctttgg gggactctat aatagcagct tgagatcagt 4800

 gtctagaaga ctgttctgca atttgctgcc aaatgcatct caggttttta 4850

 aagtcattgt ttcttgctca tggtggctca tttattacat agtcccctca 4900

 ccccactaat ggataatggg aggaaaagtt gctgcttcct tcagcatcaa 4950

 agcctttcct tgggaatctg cctccctcca tggcaggggt ggattcggga 5000

 gctgggagta accaggcaaa gtcaaccaga tgcctagctc ctgctgagac 5050

 ccaggtccta tggcagctcc tcattagatt aaaggagacc acttccaaag 5100

 caggtgctgc atggctcacc atcatatgcc ccaaacaact gaaagttggc 5150

 ggttatcacc agactgtgag tttctggcaa gtagcttggg gaagctgaat 5200

 aaactctagg cccagggcta ctaaagactt caggatagaa ttctccatca 5250

 aatatacagc ataagtaaaa ctgctctgca ctgtttaatc catttccaag 5300

 gggcttagaa aagctaacaa gggtgtgtcc cctgtcctgc cccaccggtt 5350

 tgctggcttt gtaataacat aagaccattg tggttgttgg tgtcagatac 5400

 cttcccatcc tgagctctct cacctacctg ctctctctcc tagagcagga 5450

 tactggggta cttttaagaa gggtgctcct tttaagatgc ccagaaaagc 5500

 tgtatttaac tcttgctatt tgtaacttgg ggatggtctc ccctgcccca 5550

 gggcacataa gagcaaaggc tccaatggtc agtggatgac tctgcaaaag 5600

 tgaccccctg tgccagaagc tatagccctc tccccaacag gtctctcttg 5650

 ttggccagag ggcctgcttc ccatgggcat tgcaagtgcc accgtgcggg 5700

 gcctggctct gcacacccag gaaaagtctg cagaccccca gccctccgca 5750

 ataattcacc agaccagaag ccactggtgt acagagaaca cttaaaaaaa 5800

 tgtattttat gtgaaaaaaa attaaaactc tgtatactgt atcagcagct 5850

 ttgtgtaaaa atggcaatca agagagtcta atatatttaa aactttttta 5900

 aaaaaaatct tcgcggatct ttgatatcgt actgaggtaa cttccacgta 5950

 gccccttgcc acgcggcacc ggtgggcctt gggtccaaaa ctgtggctca 6000

 gccacatccc aaagggggca catgtccctg gagttgcttc cagctgccaa 6050

 ggcctgtgac agaattcgct gttaagagtt tttaattaaa attattaaat 6100

 tccttttaat aac 6113

<210> 2665
<211> 567
<212> PRT
<213> Homo sapien

<400> 2665
 Met Ala Ser His Val Asp Leu Leu Thr Glu Leu Gln Leu Leu Glu
   1               5                  10                  15

 Lys Val Pro Thr Leu Glu Arg Leu Arg Ala Ala Gln Lys Arg Arg
                  20                  25                  30

 Ala Gln Gln Leu Lys Lys Trp Ala Gln Tyr Glu Gln Asp Leu Gln
                  35                  40                  45

 His Arg Lys Arg Lys His Glu Arg Lys Arg Ser Thr Gly Gly Arg
                  50                  55                  60

 Arg Lys Lys Val Ser Phe Glu Ala Ser Val Ala Leu Leu Glu Ala
                  65                  70                  75

 Ser Leu Arg Asn Asp Ala Glu Glu Val Arg Tyr Phe Leu Lys Asn
                  80                  85                  90

 Lys Val Ser Pro Asp Leu Cys Asn Glu Asp Gly Leu Thr Ala Leu
                  95                 100                 105

 His Gln Cys Cys Ile Asp Asn Phe Glu Glu Ile Val Lys Leu Leu
                 110                 115                 120

 Leu Ser His Gly Ala Asn Val Asn Ala Lys Asp Asn Glu Leu Trp
                 125                 130                 135

 Thr Pro Leu His Ala Ala Ala Thr Cys Gly His Ile Asn Leu Val
                 140                 145                 150

 Lys Ile Leu Val Gln Tyr Gly Ala Asp Leu Leu Ala Val Asn Ser
                 155                 160                 165

 Asp Gly Asn Met Pro Tyr Asp Leu Cys Glu Asp Glu Pro Thr Leu
                 170                 175                 180

 Asp Val Ile Glu Thr Cys Met Ala Tyr Gln Gly Ile Thr Gln Glu
                 185                 190                 195

 Lys Ile Asn Glu Met Arg Val Ala Pro Glu Gln Gln Met Ile Ala
                 200                 205                 210

 Asp Ile His Cys Met Ile Ala Ala Gly Gln Asp Leu Asp Trp Ile
                 215                 220                 225

 Asp Ala Gln Gly Ala Thr Leu Leu His Ile Ala Gly Ala Asn Gly
                 230                 235                 240

 Tyr Leu Arg Ala Ala Glu Leu Leu Leu Asp His Gly Val Arg Val
                 245                 250                 255

 Asp Val Lys Asp Trp Asp Gly Trp Glu Pro Leu His Ala Ala Ala
                 260                 265                 270

 Phe Trp Gly Gln Met Gln Met Ala Glu Leu Leu Val Ser His Gly
                 275                 280                 285

 Ala Ser Leu Ser Ala Arg Thr Ser Met Asp Glu Met Pro Ile Asp
                 290                 295                 300

 Leu Cys Glu Glu Glu Glu Phe Lys Val Leu Leu Leu Glu Leu Lys
                 305                 310                 315

 His Lys His Asp Val Ile Met Lys Ser Gln Leu Arg His Lys Ser
                 320                 325                 330

 Ser Leu Ser Arg Arg Thr Ser Ser Ala Gly Ser Arg Gly Lys Val
                 335                 340                 345

 Val Arg Arg Ala Ser Leu Ser Asp Arg Thr Asn Leu Tyr Arg Lys
                 350                 355                 360

 Glu Tyr Glu Gly Glu Ala Ile Leu Trp Gln Arg Ser Ala Ala Glu
                 365                 370                 375

 Asp Gln Arg Thr Ser Thr Tyr Asn Gly Asp Ile Arg Glu Thr Arg
                 380                 385                 390

 Thr Asp Gln Glu Asn Lys Asp Pro Asn Pro Arg Leu Glu Lys Pro
                 395                 400                 405

 Val Leu Leu Ser Glu Phe Pro Thr Lys Ile Pro Arg Gly Glu Leu
                 410                 415                 420

 Asp Met Pro Val Glu Asn Gly Leu Arg Ala Pro Val Ser Ala Tyr
                 425                 430                 435

 Gln Tyr Ala Leu Ala Asn Gly Asp Val Trp Lys Val His Glu Val
                 440                 445                 450

 Pro Asp Tyr Ser Met Ala Tyr Gly Asn Pro Gly Val Ala Asp Ala
                 455                 460                 465

 Thr Pro Pro Trp Ser Ser Tyr Lys Glu Gln Ser Pro Gln Thr Leu
                 470                 475                 480

 Leu Glu Leu Lys Arg Gln Arg Ala Ala Ala Lys Leu Leu Ser His
                 485                 490                 495

 Pro Phe Leu Ser Thr His Leu Gly Ser Ser Met Ala Arg Thr Gly
                 500                 505                 510

 Glu Ser Ser Ser Glu Gly Lys Ala Pro Leu Ile Gly Gly Arg Thr
                 515                 520                 525

 Ser Pro Tyr Ser Ser Asn Gly Thr Ser Val Tyr Tyr Thr Val Thr
                 530                 535                 540

 Ser Gly Asp Pro Pro Leu Leu Lys Phe Lys Ala Pro Ile Glu Glu
                 545                 550                 555

 Met Glu Glu Lys Val His Gly Cys Cys Arg Ile Ser
                 560                 565

<210> 2666
<211> 3821
<212> DNA
<213> Homo sapien

<400> 2666
 agtctcgcgg tgctgccggg ctcagccccg tctcctcctc ttgctccctc 50

 ggccgggcgg cggtgactgt gcaccgacgt cggcgcgggc tgcaccgccg 100

 cgtccgcccg cccgccagca tggccaccac cgccacctgc acccgtttca 150

 ccgacgacta ccagctcttc gaggagcttg gcaagggtgc tttctctgtg 200

 gtccgcaggt gtgtgaagaa aacctccacg caggagtacg cagcaaaaat 250

 catcaatacc aagaagttgt ctgcccggga tcaccagaaa ctagaacgtg 300

 aggctcggat atgtcgactt ctgaaacatc caaacatcgt gcgcctccat 350

 gacagtattt ctgaagaagg gtttcactac ctcgtgtttg accttgttac 400

 cggcggggag ctgtttgaag acattgtggc cagagagtac tacagtgaag 450

 cagatgccag ccactgtata catcagattc tggagagtgt taaccacatc 500

 caccagcatg acatcgtcca cagggacctg aagcctgaga acctgctgct 550

 ggcgagtaaa tgcaagggtg ccgccgtcaa gctggctgat tttggcctag 600

 ccatcgaagt acagggagag cagcaggctt ggtttggttt tgctggcacc 650

 ccaggttact tgtcccctga ggtcttgagg aaagatccct atggaaaacc 700

 tgtggatatc tgggcctgcg gggtcatcct gtatatcctc ctggtgggct 750

 atcctccctt ctgggatgag gatcagcaca agctgtatca gcagatcaag 800

 gctggagcct atgatttccc atcaccagaa tgggacacgg taactcctga 850

 agccaagaac ttgatcaacc agatgctgac cataaaccca gcaaagcgca 900

 tcacggctga ccaggctctc aagcacccgt gggtctgtca acgatccacg 950

 gtggcatcca tgatgcatcg tcaggagact gtggagtgtt tgcgcaagtt 1000

 caatgcccgg agaaaactga agggtgccat cctcacgacc atgcttgtct 1050

 ccaggaactt ctcagctgcc aaaagcctat tgaacaagaa gtcggatggc 1100

 ggtgtcaagc cacagagcaa caacaaaaac agtctcgtaa gcccagccca 1150

 agagcccgcg cccttgcaga cggccatgga gccacaaacc actgtggtac 1200

 acaacgctac agatgggatc aagggctcca cagagagctg caacaccacc 1250

 acagaagatg aggacctcaa agctgccccg ctccgcactg ggaatggcag 1300

 ctcggtgcct gaaggacgga gctcccggga cagaacagcc ccctctgcag 1350

 gcatgcagcc ccagccttct ctctgctcct cagccatgcg aaaacaggag 1400

 atcattaaga ttacagaaca gctgattgaa gccatcaaca atggggactt 1450

 tgaggcctac acgaagattt gtgatccagg cctcacttcc tttgagcctg 1500

 aggcccttgg taacctcgtg gaggggatgg atttccataa gttttacttt 1550

 gagaatctcc tgtccaagaa cagcaagcct atccatacca ccatcctaaa 1600

 cccacacgtc cacgtgattg gggaggacgc agcgtgcatc gcctacatcc 1650

 gcctcaccca gtacatcgac gggcagggtc ggcctcgcac cagccagtca 1700

 gaagagaccc gggtctggca ccgtcgggat ggcaagtggc tcaatgtcca 1750

 ctatcactgc tcaggggccc ctgccgcacc gctgcagtga gctcagccac 1800

 aggggcttta ggagattcca gccggaggtc caaccttcgc agccagtggc 1850

 tctggagggc ctgagtgaca gcggcagtcc tgtttgtttg aggtttaaaa 1900

 caattcaatt acaaaagcgg cagcagccaa tgcacgcccc tgcatgcagc 1950

 cctcccgccc gcccttcgtg tctgtctctg ctgtaccgag gtgtttttta 2000

 catttaagaa aaaaaaaaaa gaaaaaaaga ttgtttaaaa aaaaaaggaa 2050

 tccataccat gatgcgtttt aaaaccaccg acagcccttg ggttggcaag 2100

 aaggcaggag tatgtatgag gtccatcctg gcatgagcag tggctcaccc 2150

 accggccttg aagaggtgag cttggcctct ctggtcccca tggacttagg 2200

 gggaccaggc aagaactctg acagagcttt gggggccgtg atgtgattgc 2250

 agctcctgag gtggcctgct taccccaggt ctaggaatga acttctttgg 2300

 aacttgcata ggcgcctaga atggggctga tgagaacatc gtgaccatca 2350

 gacctacttg ggagagaacg cagagctccc agcctgctgt ggaggcagct 2400

 gagaagtggt ggcctcagga ctgagagccc ggacgttgct gtactgtctt 2450

 gtttagtgta gaagggaaga gaattggtgc tgcagaagtg tacccgccat 2500

 gaagccgatg agaaacctcg tgttagtctg acatgcactc actcatccat 2550

 ttctatagga tgcacaatgc atgtgggccc taatattgag gccttatccc 2600

 tgcagctagg agggggaggg gttgttgctg ctttgcttcg tgttttcttc 2650

 taacctggca aggagagagc caggccctgg tcagggctcc cgtgccgcct 2700

 ttggcggttc tgtttctgtg ctgatctgga ccatctttgt cttgcctttt 2750

 cacggtagtg gtccccatgc tgaccctcat ctgggcctgg gccctctgcc 2800

 aagtgcccct gtgggatggg aggagtgagg cagtgggaga agaggtggtg 2850

 gtcgtttcta tgcattcagg ctgcctttgg ggctgcctcc cttcttattc 2900

 ttccttgctg cacgtccatc tcttttcctg tctttgagat tgacctgact 2950

 gctctggcaa gaagaagagg tgtccttaca gaggcctctt tactgaccaa 3000

 ctgaagtata gacttactgc tggacaatct gcatgggcat cacccctccc 3050

 cgcatgtaac ccaaaagagg tgtccagagc caaggcttct accttcattg 3100

 tccctctctg tgctcaagga gttccattcc aggaggaaga gatctatacc 3150

 ctaagcagat agcaaagaag ataatggagg agcaattggt catggccttg 3200

 gtttccctca aaacaacgct gcagatttat ctgcacaaac atctccactt 3250

 ttgggggaaa ggtgggtaga ttccagttcc ctggactacc ttcaggaggc 3300

 acgagagctg ggagaagagg caaagctaca ggtttacttg ggagccagct 3350

 gagaagagag cagactcaca ggtgctggtg cttggattta gccaggctcc 3400

 tccgagcacc tcatgcatgt cccagcccct gggccctagc cctttcctgc 3450

 cctgcagtct gcagtgccag cacgcaaatc ccttcaccac agggtttcgt 3500

 tttgctggct tgaagacaaa tggtcttaga attcattgag acccatagct 3550

 tcatatggct gctccagccc cacttcttag cattcttact cctcttctgg 3600

 ggctaatgtc agcatctata gacaatagac tattaaaaaa tcacctttta 3650

 aacaagaaac ggaaggcatt tgatgcagaa tttttgcatg acaacataga 3700

 aataatttaa aaatagtgtt tgttctgaat gttggtagac ccttcatagc 3750

 tttgttacaa tgaaaccttg aactgaaaat atttaataaa ataaccttta 3800

 aacagtcaaa aaaaaaaaaa a 3821

<210> 2667
<211> 556
<212> PRT
<213> Homo sapien

<400> 2667
 Met Ala Thr Thr Ala Thr Cys Thr Arg Phe Thr Asp Asp Tyr Gln
   1               5                  10                  15

 Leu Phe Glu Glu Leu Gly Lys Gly Ala Phe Ser Val Val Arg Arg
                  20                  25                  30

 Cys Val Lys Lys Thr Ser Thr Gln Glu Tyr Ala Ala Lys Ile Ile
                  35                  40                  45

 Asn Thr Lys Lys Leu Ser Ala Arg Asp His Gln Lys Leu Glu Arg
                  50                  55                  60

 Glu Ala Arg Ile Cys Arg Leu Leu Lys His Pro Asn Ile Val Arg
                  65                  70                  75

 Leu His Asp Ser Ile Ser Glu Glu Gly Phe His Tyr Leu Val Phe
                  80                  85                  90

 Asp Leu Val Thr Gly Gly Glu Leu Phe Glu Asp Ile Val Ala Arg
                  95                 100                 105

 Glu Tyr Tyr Ser Glu Ala Asp Ala Ser His Cys Ile His Gln Ile
                 110                 115                 120

 Leu Glu Ser Val Asn His Ile His Gln His Asp Ile Val His Arg
                 125                 130                 135

 Asp Leu Lys Pro Glu Asn Leu Leu Leu Ala Ser Lys Cys Lys Gly
                 140                 145                 150

 Ala Ala Val Lys Leu Ala Asp Phe Gly Leu Ala Ile Glu Val Gln
                 155                 160                 165

 Gly Glu Gln Gln Ala Trp Phe Gly Phe Ala Gly Thr Pro Gly Tyr
                 170                 175                 180

 Leu Ser Pro Glu Val Leu Arg Lys Asp Pro Tyr Gly Lys Pro Val
                 185                 190                 195

 Asp Ile Trp Ala Cys Gly Val Ile Leu Tyr Ile Leu Leu Val Gly
                 200                 205                 210

 Tyr Pro Pro Phe Trp Asp Glu Asp Gln His Lys Leu Tyr Gln Gln
                 215                 220                 225

 Ile Lys Ala Gly Ala Tyr Asp Phe Pro Ser Pro Glu Trp Asp Thr
                 230                 235                 240

 Val Thr Pro Glu Ala Lys Asn Leu Ile Asn Gln Met Leu Thr Ile
                 245                 250                 255

 Asn Pro Ala Lys Arg Ile Thr Ala Asp Gln Ala Leu Lys His Pro
                 260                 265                 270

 Trp Val Cys Gln Arg Ser Thr Val Ala Ser Met Met His Arg Gln
                 275                 280                 285

 Glu Thr Val Glu Cys Leu Arg Lys Phe Asn Ala Arg Arg Lys Leu
                 290                 295                 300

 Lys Gly Ala Ile Leu Thr Thr Met Leu Val Ser Arg Asn Phe Ser
                 305                 310                 315

 Ala Ala Lys Ser Leu Leu Asn Lys Lys Ser Asp Gly Gly Val Lys
                 320                 325                 330

 Pro Gln Ser Asn Asn Lys Asn Ser Leu Val Ser Pro Ala Gln Glu
                 335                 340                 345

 Pro Ala Pro Leu Gln Thr Ala Met Glu Pro Gln Thr Thr Val Val
                 350                 355                 360

 His Asn Ala Thr Asp Gly Ile Lys Gly Ser Thr Glu Ser Cys Asn
                 365                 370                 375

 Thr Thr Thr Glu Asp Glu Asp Leu Lys Ala Ala Pro Leu Arg Thr
                 380                 385                 390

 Gly Asn Gly Ser Ser Val Pro Glu Gly Arg Ser Ser Arg Asp Arg
                 395                 400                 405

 Thr Ala Pro Ser Ala Gly Met Gln Pro Gln Pro Ser Leu Cys Ser
                 410                 415                 420

 Ser Ala Met Arg Lys Gln Glu Ile Ile Lys Ile Thr Glu Gln Leu
                 425                 430                 435

 Ile Glu Ala Ile Asn Asn Gly Asp Phe Glu Ala Tyr Thr Lys Ile
                 440                 445                 450

 Cys Asp Pro Gly Leu Thr Ser Phe Glu Pro Glu Ala Leu Gly Asn
                 455                 460                 465

 Leu Val Glu Gly Met Asp Phe His Lys Phe Tyr Phe Glu Asn Leu
                 470                 475                 480

 Leu Ser Lys Asn Ser Lys Pro Ile His Thr Thr Ile Leu Asn Pro
                 485                 490                 495

 His Val His Val Ile Gly Glu Asp Ala Ala Cys Ile Ala Tyr Ile
                 500                 505                 510

 Arg Leu Thr Gln Tyr Ile Asp Gly Gln Gly Arg Pro Arg Thr Ser
                 515                 520                 525

 Gln Ser Glu Glu Thr Arg Val Trp His Arg Arg Asp Gly Lys Trp
                 530                 535                 540

 Leu Asn Val His Tyr His Cys Ser Gly Ala Pro Ala Ala Pro Leu
                 545                 550                 555

 Gln


<210> 2668
<211> 2309
<212> DNA
<213> Homo sapien

<400> 2668
 acctacgtcc ttcccacggc ccggccagtt aatctgctgc agttctgtcg 50

 accaggtcaa tgacagcgtt tacaggaaag tactgcctgc cttggtcatc 100

 ccggctcatt atatgaaact ccccagggac cactcctatg tcagccagcc 150

 cctcgtcgtc ccggctgatc agcagcttga gatagaaaga ctacaggctg 200

 agctgtccaa tccccatgcc gggatcttcc cacacccgtc ctcacagatc 250

 cagccccagc ccctgtcttc ccaggccatc tctcagcagc acctgcagga 300

 tgcgggcacc cgggagtgga gccctcagaa cgcatccatg tcggagtctc 350

 tctccatcca agcttccctg aacgacgcgg ctttggctca gatgaacagt 400

 gaggtgcagc tcctgactga aaaggccctg atggagcttg ggggtgggaa 450

 gccgcttccg cacccccggg cgtggttcgt ctccttggat ggcaggtcca 500

 acgctcacgt tagacattca tacattgatc tccaaagagc tggaaggaac 550

 ggaagtaatg atgccagttt ggactctggc gtagatatga atgaaccaaa 600

 atcagcccgg aagggaaggg gagatgcttt gtctctgcag cagaactacc 650

 cgcccgtcca agagcaccag cagaaagagc ctcgagcccc agacagcacg 700

 gcctacacgc agctcgtgta cctggatgac gtggaacaga gtggtagcga 750

 atgtgggacc acggtctgta cccccgagga cagtgccctg cgatgcttgt 800

 tggaggggtc gagtcggaga agtggtggcc agctgcccag cctgcaggag 850

 gagacgacca gacggactgc ggatgccccc tcggagccag cagccagccc 900

 ccaccagaga agatctgccc acgaggaaga ggaagacgat gatgatgatg 950

 accaaggaga agacaagaaa agcccctggc agaaacggga ggagaggccc 1000

 ctgatggcgt ttaacattaa atgagctatc gcagacccac ctgactgtgg 1050

 aatataaaat tgccaaatat cctttctcat ggaagcgcgt acccgttcgt 1100

 ggaggaaacg gaacggcagc ccagccgtgg gacggacgtg gacgtttact 1150

 gcattcctgt ttgccgtgta aatgttagaa aggaattaaa gttattactc 1200

 ggaataaagg atgactttgg cggatgtcgc ccctgcaagg aggtggctga 1250

 aagtggtgtc cagatgtcct tccgaggact cggcgtatcc gccgccaggg 1300

 acattaagaa accgcacgtg atgtcgctat gctctaacga tcacctcagt 1350

 tctccctagg attctgggaa cagatgaaac tttttgcatc gcttgagtca 1400

 tttttatcac aataatccta ctgtgaagct gtcgttgaga acttaggttg 1450

 gcacgtagcg tctcaaggta tgcgttctct caaaggaaag ctatgcatcg 1500

 ctgcttcgtt gtctgatttt gcttagattt tgctttggtt aggttgcgtt 1550

 ttggggtttg cctttttttg ttgtcgctta aatgcaattt ggttgtaaag 1600

 atttgattcc tttgtgttca tctgttccgc ttctcagcgg tccatctcag 1650

 cgtctccctt caggaaccgc tgagtgtcct ctcttaacat ccaagccttt 1700

 taatgaaatc gtactgaaat ctgtatcagc taagagtcct ccaatcctgg 1750

 tcccattaac tccaagtgcc tttttgacag tgacaacaga cagtccctcg 1800

 ctttttgttg ttgtttgttt tcttaacccc tttaatggaa ctgcctggat 1850

 tttatacagt tattaaagga tgtctctttt gctttaaact gcatgctgcc 1900

 aagtgccatt tggggtcagc atcctcgttt caacacagtg tgctctctag 1950

 ttatcatgtg taacgtgggt tctgtttagc gaagatagac tagaggacac 2000

 gttagagatg cccttccctg ctccatccct gtggcaccat tatggttttt 2050

 ttggctgttt gtatatacgg ttacgtatta actctggaat cctatgggct 2100

 catcttgctc acccaatgtg ggagtctggt ttgagcaagc gagctgaatg 2150

 tgactattaa aaaaaattta aaaaaaaaaa agaaaatctt atgtactatc 2200

 caaaagtgcc agaatgactc ttctgtgcat tcttcttaaa gagctgcttg 2250

 gttatccaaa aatgaaaatt caaaataaac tctgaagaaa aggaaaaaaa 2300

 aaaaaaaaa 2309

<210> 2669
<211> 340
<212> PRT
<213> Homo sapien

<400> 2669
 Pro Thr Ser Phe Pro Arg Pro Gly Gln Leu Ile Cys Cys Ser Ser
   1               5                  10                  15

 Val Asp Gln Val Asn Asp Ser Val Tyr Arg Lys Val Leu Pro Ala
                  20                  25                  30

 Leu Val Ile Pro Ala His Tyr Met Lys Leu Pro Arg Asp His Ser
                  35                  40                  45

 Tyr Val Ser Gln Pro Leu Val Val Pro Ala Asp Gln Gln Leu Glu
                  50                  55                  60

 Ile Glu Arg Leu Gln Ala Glu Leu Ser Asn Pro His Ala Gly Ile
                  65                  70                  75

 Phe Pro His Pro Ser Ser Gln Ile Gln Pro Gln Pro Leu Ser Ser
                  80                  85                  90

 Gln Ala Ile Ser Gln Gln His Leu Gln Asp Ala Gly Thr Arg Glu
                  95                 100                 105

 Trp Ser Pro Gln Asn Ala Ser Met Ser Glu Ser Leu Ser Ile Gln
                 110                 115                 120

 Ala Ser Leu Asn Asp Ala Ala Leu Ala Gln Met Asn Ser Glu Val
                 125                 130                 135

 Gln Leu Leu Thr Glu Lys Ala Leu Met Glu Leu Gly Gly Gly Lys
                 140                 145                 150

 Pro Leu Pro His Pro Arg Ala Trp Phe Val Ser Leu Asp Gly Arg
                 155                 160                 165

 Ser Asn Ala His Val Arg His Ser Tyr Ile Asp Leu Gln Arg Ala
                 170                 175                 180

 Gly Arg Asn Gly Ser Asn Asp Ala Ser Leu Asp Ser Gly Val Asp
                 185                 190                 195

 Met Asn Glu Pro Lys Ser Ala Arg Lys Gly Arg Gly Asp Ala Leu
                 200                 205                 210

 Ser Leu Gln Gln Asn Tyr Pro Pro Val Gln Glu His Gln Gln Lys
                 215                 220                 225

 Glu Pro Arg Ala Pro Asp Ser Thr Ala Tyr Thr Gln Leu Val Tyr
                 230                 235                 240

 Leu Asp Asp Val Glu Gln Ser Gly Ser Glu Cys Gly Thr Thr Val
                 245                 250                 255

 Cys Thr Pro Glu Asp Ser Ala Leu Arg Cys Leu Leu Glu Gly Ser
                 260                 265                 270

 Ser Arg Arg Ser Gly Gly Gln Leu Pro Ser Leu Gln Glu Glu Thr
                 275                 280                 285

 Thr Arg Arg Thr Ala Asp Ala Pro Ser Glu Pro Ala Ala Ser Pro
                 290                 295                 300

 His Gln Arg Arg Ser Ala His Glu Glu Glu Glu Asp Asp Asp Asp
                 305                 310                 315

 Asp Asp Gln Gly Glu Asp Lys Lys Ser Pro Trp Gln Lys Arg Glu
                 320                 325                 330

 Glu Arg Pro Leu Met Ala Phe Asn Ile Lys
                 335                 340

<210> 2670
<211> 9765
<212> DNA
<213> Homo sapien

<400> 2670
 gggtaaagct agtgacacag aaaggggtgg agtgctgaca tccaataatt 50

 cttctgattc tccaaccggc agtggctata atactgatgt ctctgatgat 100

 aatcttccat gtgaccggac aagcccttcc tcagacttaa atggaaattc 150

 tgtttcagat gaacaggatg aaggagtcga atctgatgat ttgaaaaaag 200

 atctacctct gatgcctcct cctccagatt catgtagcat gaagttgacc 250

 attaaagaaa tttggtttag ttttgcagct cccaccaatg tgagatctca 300

 cacacatgca ttttctaggc agctgaacct tttaagcact gcaacaccag 350

 ctgttggtgc atggcttgtt cccattgacc aactcaagtc atctttaaac 400

 aaattggaaa ctgagggaac cttgagaatt tgtgctgtta tgggatgcat 450

 aatgacagaa gcattagaga ataaaagtgt acattttccc ctaagaagta 500

 aatacaacag gcttacaaaa gttgctcgct ttctccaaga aaatccttca 550

 tgtttactat gtaatatact acaccactat ctgcaccagg caaattactc 600

 catcattgat gatgctacaa tgagcgatgg acttcctgct ttggtaactt 650

 tgaagaaagg tttagttgca ctggcaaggc agtggatgaa gtttattgtg 700

 gtgacaccag cctttaaagg agttagctta catagaccag ctcagcctct 750

 gaaacctcaa atagctatgg accatgaaca tgaagatgga cttggattgg 800

 acaatggggg tggtcttcaa agtgatacca gtgctgatgg agcagaattt 850

 gagttcgatg cagccacagt cagtgaacac acaatgctat tagaaggaac 900

 agctaaccgg cctccacctg gtagctctgg acctgtaact ggagctgaga 950

 taatgaggaa actttctaaa actcataccc atagtgactc tgcattaaaa 1000

 ataaagggca ttcacccata tcattctctg agctatacca gtggagacac 1050

 tgccactgat tctccagtgc atgttggacg tgctgggatg ccagtaaagg 1100

 acagtccaag gaaggagagc ctactcagct acctgactgg aagcttccca 1150

 agcctgcaca acctcctgga aggtactcct cagagaagca gtgctgctgt 1200

 gaaaagtagc tccctaacga gaacaggaaa tacagtagcc actgatatgt 1250

 tatctgaaca tcccttgcta tctgagccat catctgtgag tttctataat 1300

 tggatgtcaa atgctgtggg taatcgagga agtgtgttac aagaatctcc 1350

 tgttacaaaa tcaggacaca atagtcttcc cacaggtgtt gcacccaatc 1400

 ttccaacaat accctcagcc tcagatttca acactgtctt gtctagtgac 1450

 caaaatactt tggatgggac acattctcag catagcacca gtcaggatga 1500

 tgtggcaggt gtagaagaag caaaccaagg gtttcctgct gttcagcttg 1550

 ctgatgcaca ggttgttttc aagcctcttc tgagtcatac agggatccag 1600

 tcacaggata caatgccatt ctgctaccga atgtactttg gagaacacct 1650

 ttcattttca gggactttgg actgcctcag agcagatatt gtggattcag 1700

 acacagccaa agagagaaaa ggcaaaagag caagaaggca aggccatgtg 1750

 aatcttcctc cacttgagtt caaaccagca ttaatgttgg gaacctttag 1800

 catcagtgct gttgtaatgg aaaagtccgt gtgcacccct cagaactcta 1850

 ccagtgccct ttcttttcat gatctcagca agcggtatta taacaccttt 1900

 cactgcaact ttactatttc ctgtcagtca ataagccagc atgtagatat 1950

 ggctttggtt cgtcttattc atcagtttag cacaatgata gatgacatca 2000

 aagcaactca gactgatatt aaacttagca gatatacagc cggatctgct 2050

 tccccaacac ctaccttcaa aaccagaaaa catcgggact ttcgttcatc 2100

 tgactttagc cgcagttcta gaggaagtct taatggtggc aatagagtaa 2150

 ataatgcaaa gaacaaacgg accaacaatg agaataacaa aaaggaatct 2200

 cgaaacaaga attcattagg aagatctgaa agaagaacat caaaagtgtc 2250

 taggaaaggt tcaaaagatg tggtggatca catgactatt catatggatg 2300

 actctgattc aattacagtg tcagaacaaa gtgagccttc agctgagtgc 2350

 tggcagaata tgtataaatt gcttaacttc tattcactta tctccgatcc 2400

 aacaggaata ttggaaaagt cttcagaaac atttggacca gcaggagttc 2450

 ggagccctac agagccaaca tgtaaagttg tgtttgagaa tgaacaagac 2500

 aacagcagtt tgactaagac tcagaggaaa cgtagcttgg taacttctga 2550

 acctcagcat gttactctaa tagtgtttgg gattggcatg gtgaaccgca 2600

 cacacctaga ggcagatatt ggtggactaa caatggaatc agaactgaag 2650

 aggatccatg gcagttttac tcttaaggaa aaaatgaaag atgttttaca 2700

 tcaaaagatg actgagactt gtgctactgc tcatattggt ggggttaata 2750

 ttgtgctgct tgaagggatt acaccaaata tacaactgga ggattttcct 2800

 acatctccta caagtacagc caaacaagag tttctaactg tagtgaaatg 2850

 tagtattgcc aagtcccaag ccctctacag tgcccaaaga gggctgaaga 2900

 caaacaatgc tgctgtgttc aaagtaggag ctatcagtat caacattcct 2950

 cagcaccctg ccaccttaca tagcatgatg gttcgaagtt ctcaccaact 3000

 atctaaacaa atctcagacc taatcagaca gccttctaca gccccacagc 3050

 ctgtaaaaga agatattgca accccactac cttctgaaaa aaccccaaca 3100

 agtgttaatc aaactcctgt tgaaacaaat gaatttcctc agctaccaga 3150

 aggcttagaa aagaagccta ttgttcttaa attcagtgcc atgttagatg 3200

 gtatagccat tggagcagca cttttaccat ctctgaaagc agaatacaag 3250

 atgggaagaa tgagaagtca tggaatgaca ggtgcacaga caagatttac 3300

 atttgagctg ccaaatcaca gattgcgttt tacttcaaaa gtttctgcca 3350

 cagatatgtc aaccattcct ccttctgcca gtcttaacct tccccctgtt 3400

 accatgtcag ggaaatatat aatggaagaa catgatagtt attcggatca 3450

 ggtgtggagt atagatgaac tgccttctaa acaaggttac tatttacagg 3500

 gaaattatct gcgttgtgtg gcagaagttg gttcctttga acataatctt 3550

 acaactgatc ttctaaacca cttggtattt gtacagaaag tgttcatgaa 3600

 ggaagttaat gaagtaatac aaaaagtttc tggtggggag cagcctattc 3650

 ctctctggaa cgaacatgat ggaacagcag atggagataa acctaaaatt 3700

 ctcctctatt ccctaaactt gcagttcaag ggtattcaag taacggccac 3750

 tactccatca atgagagctg taagatttga aactggattg attgaactgg 3800

 aactttctaa ccgacttcaa accaaagctt caccaggaag tagcagctat 3850

 ctgaaactgt ttggcaaatg ccaggtggat ttaaatctgg cattaggaca 3900

 aattgtcaaa catcaggttt atgaggaagc tggttctgat tttcatcaag 3950

 ttgcctattt taaaaccaga attggattaa gaaatgccct ccgagaagaa 4000

 atcagtggtt cttcagatag ggaagctgtg cttattactt tgaatagacc 4050

 aattgtttat gcacagcctg tggcctttga tagagctgtg ctgttttggc 4100

 tgaattataa ggccgcctat gacaactgga atgaacaacg aatggcttta 4150

 cataaggata ttcatatggc tacaaaggaa gtagtagata tgctacctgg 4200

 tatccagcaa acatcagccc aggcctttgg gactcttttt ctccagctca 4250

 ctgtcaatga tctgggaatt tgcctaccta tcacaaatac tgcacagtct 4300

 aatcatactg gagaccttga cactggttct gctttggtat taaccattga 4350

 aagtactctc atcactgcat gctcttcaga gtctctggtt agcaaagggc 4400

 atttcaaaaa cttttgtatc cgttttgctg atggatttga gacatcatgg 4450

 gatgactgga aaccagaaat tcatggggat ttagtgatga atgcctgtgt 4500

 agttccagat ggcacctatg aagtatgttc aagaactaca ggacaagcag 4550

 cagctgaaag cagtagtgct ggaacctgga cactcaacgt attgtggaaa 4600

 atgtgtggga ttgatgttca catggatcct aacattggca aaaggcttaa 4650

 tgctctgggc aatactctta caacactgac aggagaggaa gacatagatg 4700

 acattgctga cttaaattca gtgaacatag ctgacctgtc agatgaggat 4750

 gaagttgata ctatgtctcc cactatccat actgaagcca cagattatcg 4800

 aagacaggca gcatctgcta gccagccggg agaacttaga ggaagaaaaa 4850

 ttatgaagcg tatagtggat atcagagaac tgaatgaaca ggccaaagta 4900

 atagatgatc tgaaaaaatt aggtgcaagt gaaggaacca taaaccagga 4950

 aattcaacgt taccaacagt tagaatctgt ggctgtgaat gacattagaa 5000

 gagatgttcg taaaaaatta cggaggtcca gtatgcgggc tgcttcccta 5050

 aaggataagt ggggtttgag ttacaaacca agttacagcc gatcaaaaag 5100

 catttctgct tctggaagac cacctcttaa gcgaatggaa agggcaagtt 5150

 ctcgagtagg agaaactgaa gagctcccag aaatccgtgt ggatgcagca 5200

 tctcctggac ctagagtaac ttttaatatc caggatacat ttccagagga 5250

 gacagaactg gaccttttgt cagtaaccat tgaaggtcca tcccattatt 5300

 catcaaatag tgaaggatca tgttctgtgt tcagttctcc caaaactcca 5350

 ggaggctttt caccaggcat tcctttccaa actgaagagg gccgacggga 5400

 tgacagtttg tcttctacca gtgaagattc cgagaaggat gaaaaagatg 5450

 aagaccatga gagggaaagg ttttatattt acaggaaacc ctcacatacg 5500

 tctcgtaaaa aagcaacagg ctttgctgct gttcatcagc tatttacaga 5550

 acgctggcca acaacaccag tcaatagaag tcttagtggc acagctacag 5600

 agagaaatat tgactttgaa cttgatatac gggttgaaat tgatagtgga 5650

 aaatgtgtac tccacccaac cacccttcta caagaacatg atgatataag 5700

 tttgagaagg agttatgatc gaagttccag gagcttagat caagattcac 5750

 cttcaaaaaa gaagaagttt caaactaatt atgcttctac cacccattta 5800

 atgaccggca agaaagtgcc atcatctcta cagacaaagc ctagtgactt 5850

 agaaacaaca gtattttaca ttcccggagt tgatgtaaag ttgcattaca 5900

 attccaagac gctaaagact gaatcaccta atgcctccag gggatcttcc 5950

 ttgccaagaa cactgtccaa agagtccaag ctgtatggta tgaaagatag 6000

 tgcaacatct cctccttctc ctcctttacc ttccactgtc cagagcaaga 6050

 ctaacacctt acttcctccc cagcccccac ctattcctgc agccaaagga 6100

 aaaggaagtg gaggagtaaa aacagccaag ttatatgcct gggtagcact 6150

 tcagtcattg ccagaagaaa tggttattag tccctgccta ttagactttc 6200

 tggaaaaagc tctggaaact atcccaatta caccagttga aaggaattat 6250

 acagctgtca gctcacaaga tgaagatatg ggacattttg aaataccaga 6300

 tcctatggaa gaatcaacaa catcactagt gtcgtcttca acatctgctt 6350

 actcttcctt ccctgtagat gttgtggttt atgtacgagt tcagccctca 6400

 cagatcaaat ttagctgttt accagtatca agagtagaat gcatgttaaa 6450

 gctgccatcc ctggatttgg tgttttcttc aaaccgagga gaactggaga 6500

 ctttagggac tacatatcct gcagagactt tatcccctgg aggtaatgct 6550

 actcagagtg gaacaaagac ttctgctagc aaaactggaa taccaggttc 6600

 atcgggatta ggcagccctc ttggccgaag tcgacatagt agtagtcagt 6650

 cagacctgac cagttccagc agtagttcat ctggcttgag cttcactgca 6700

 tgcatgtctg acttttccct ttatgtattt catccatatg gagcagggaa 6750

 acaaaaaact gctgtttctg gcctcacacc tggatcagga ggattaggga 6800

 atgtggatga ggagcccact tcagtcactg gtcgaaaaga ttcactcagt 6850

 ataaaccttg agtttgtaaa agtgagtttg tcacggatca ggcgttcagg 6900

 aggtgcctca ttttttgaaa gtcagtctgt aagcaagtct gcaagcaaaa 6950

 tggatactac gttaataaat atatctgctg tttgtgatat agggtctgcc 7000

 tcctttaaat atgatatgcg ccgactcagt gaaattctgg catttccaag 7050

 agcatggtat agaagaagta ttgcaagacg tctattcctt ggagaccaaa 7100

 ctataaattt gccaacatct ggcccaggga cacctgattc cattgaaggg 7150

 gtaagccaac acctttcccc tgaatcatca agaaaagctt actgcaagac 7200

 ctgggagcag ccaagtcagt cagcctcctt cacccacatg cctcagtcac 7250

 ctaatgtgtt caatgagcat atgacaaaca gcaccatgtc accagggaca 7300

 gtaggacaga gcctaaaatc cccagcttcc ataagatcaa ggagtgtatc 7350

 tgattcttca gttcctcgaa gagattcact ttcaaaaaca tcaactcctt 7400

 ttaacaaatc aaacaaagca gcaagccaac aagggacccc atgggaaaca 7450

 cttgtcgtgt ttgctatcaa cttgaagcaa ttaaacgttc aaatgaatat 7500

 gagtaatgta atgggaaata caacttggac aactagtggt ttgaagagcc 7550

 agggccgtct gtcagtagga agtaatcgtg atcgagagat cagcatgtct 7600

 gttggtctgg gaagatcaca attagattct aaaggaggag tagttggagg 7650

 gaccatagat gtcaatgctt tggagatggt tgctcatatt tctgaacatc 7700

 caaatcagca acccagtcac aaaattcaga ttactatggg ttctactgaa 7750

 gctcgtgttg attacatggg ctcaagtatc ctcatgggca tcttcagtaa 7800

 tgctgatctt aagcttcagg atgaatggaa agtaaacttg tataatacat 7850

 tggattcaag cataactgat aaaagtgaga ttttcgtcca tggagatttg 7900

 aagtgggata ttttccaagt aatgatatca aggtcaacca caccagatct 7950

 gataaaaata ggaatgaagc tccaggaatt tttcacacaa caatttgata 8000

 ccagcaaacg agctctgtct acctggggac cagttcctta ccttccgcca 8050

 aagacaatga ctagcaacct agaaaaaagt tcacaagaac aattacttga 8100

 tgcagcacat catcgacact ggcctggagt attgaaggtg gtatcaggat 8150

 gccacatatc cttatttcag attccattac cagaagatgg aatgcaattt 8200

 ggaggatcaa tgagcttaca tggaaatcat atgacactgg catgttttca 8250

 tggtccaaat tttcgttcaa aatcttgggc cctttttcat ttagaagaac 8300

 caaatattgc tttttggact gaagctcaga aaatctggga agatggctcc 8350

 agtgatcatt ctacatatat tgtacaaaca ctagattttc acctgggtca 8400

 taatactatg gttaccaaac catgtggtgc tttggaaagt cctatggcaa 8450

 caataaccaa gataacaagg cgtcgccatg aaaatccacc ccatggagta 8500

 gcaagtgtga aagaatggtt caattatgtt acagctacaa ggaatgaaga 8550

 gctaaatctg cttcgtaatg ttgatgctaa caacactgag aatagcacta 8600

 ctgtgaagaa ttctagtttg ttgagtggat tcagaggagg ttctagctac 8650

 aaccatgaaa cagagactat ctttgcatta ccaaggatgc agcttgactt 8700

 taaatccatt catgttcaag aaccacagga gccttcatta caggatgcca 8750

 gcctgaagcc aaaagtagaa tgtagtgtgg tgacagagtt cactgaccac 8800

 atttgtgtga ctatggatgc tgagctcatc atgtttcttc atgatttagt 8850

 atcagcttat cttaaagaaa aagaaaaagc catctttcca cctcggattt 8900

 tatctactcg accaggacaa aaaagtccaa ttattataca tgacgacaat 8950

 tcctctgata aagatagaga agatagcatc acttatacta ctgtggactg 9000

 gagagatttt atgtgcaata catggcatct agaacctact cttagattaa 9050

 tttcttggac tggaagaaag attgatccag taggtgttga ttatattctt 9100

 caaaaattgg gctttcatca tgctaggact actattccta aatggcttca 9150

 aagaggagtc atggatccac tggacaaggt tctgtcagtt cttatcaaaa 9200

 agctcggtac tgcactacag gatgaaaagg aaaagaaagg caaagacaaa 9250

 gaagaacact aaaaaagtaa tttgatctgt gaacaaatta tgattgtgtc 9300

 tgttttatta cactggagtg tttttttagt ataataattt gaaatataac 9350

 tttaaaataa ttctaaattt gtggctataa ttaaaagttt gtaagttaac 9400

 ctgttctagt tccatcattc tgtgtacagt gaagtattgc atgataatgt 9450

 aaattttgtg aaaaactaga ttaaaatata taactgcttg ttatggttta 9500

 taattatata atgtgcaata caattcctgc atctttaaaa tgtctgcaga 9550

 ataactgtga atttttttgt tattggattg gccgtaactt ttagaaaaaa 9600

 atcttgttga tgataatgtg attttgggga ggtcattaat tgctttttct 9650

 tttttaaatg tagacttata taaatacctg tttgtatata gcttgagtaa 9700

 ttgtgatatg attgtatacc actaaaatat tgttaactat tataataaag 9750

 tcacagtaat ggttt 9765

<210> 2671
<211> 1142
<212> DNA
<213> Homo sapien

<400> 2671
 cttttccaag cggctgccga agatggcgga ggtgcaggtc ctggtgcttg 50

 atggtcgagg ccatctcctg ggccgcctgg cggccatcgt ggctaaacag 100

 gtactgctgg gccggaaggt ggtggtcgta cgctgtgaag gcatcaacat 150

 ttctggcaat ttctacagaa acaagttgaa gtacctggct ttcctccgca 200

 agcggatgaa caccaaccct tcccgaggcc cctaccactt ccgggccccc 250

 agccgcatct tctggcggac cgtgcgaggt atgctgcccc acaaaaccaa 300

 gcgaggccag gccgctctgg accgtctcaa ggtgtttgac ggcatcccac 350

 cgccctacga caagaaaaag cggatggtgg ttcctgctgc cctcaaggtc 400

 gtgcgtctga agcctacaag aaagtttgcc tatctggggc gcctggctca 450

 cgaggttggc tggaagtacc aggcagtgac agccaccctg gaggagaaga 500

 ggaaagagaa agccaagatc cactaccgga agaagaaaca gctcatgagg 550

 ctacggaaac aggccgagaa gaacgtggag aagaaaattg acaaatacac 600

 agaggtcctc aagacccacg gactcctggt ctgagcccaa taaagactgt 650

 taattcctca tgcgttgcct gcccttcctc cattgttgcc ctggaatgta 700

 cgggacccag gggcagcagc agtccaggtg ccacaggcag ccctgggaca 750

 taggaagctg ggagcaagga aagggtctta gtcactgcct cccgaagttg 800

 cttgaaagca ctcggagaat tgtgcaggtg tcatttatct atgaccaata 850

 ggaagagcaa ccagttacta tgagtgaaag ggagccagaa gactgattgg 900

 agggccctat cttgtgagtg gggcatctgt tggactttcc acctggtcat 950

 atactctgca gctgttagaa tgtgcaagca cttggggaca gcatgagctt 1000

 gctgttgtac acagggtatt tctagaagca gaaatagact gggaagatgc 1050

 acaaccaagg ggttacaggc atcgcccatg ctcctcacct gtattttgta 1100

 atcagaaata aattgctttt aaagaaaaaa aaaaaaaaaa aa 1142

<210> 2672
<211> 203
<212> PRT
<213> Homo sapien

<400> 2672
 Met Ala Glu Val Gln Val Leu Val Leu Asp Gly Arg Gly His Leu
   1               5                  10                  15

 Leu Gly Arg Leu Ala Ala Ile Val Ala Lys Gln Val Leu Leu Gly
                  20                  25                  30

 Arg Lys Val Val Val Val Arg Cys Glu Gly Ile Asn Ile Ser Gly
                  35                  40                  45

 Asn Phe Tyr Arg Asn Lys Leu Lys Tyr Leu Ala Phe Leu Arg Lys
                  50                  55                  60

 Arg Met Asn Thr Asn Pro Ser Arg Gly Pro Tyr His Phe Arg Ala
                  65                  70                  75

 Pro Ser Arg Ile Phe Trp Arg Thr Val Arg Gly Met Leu Pro His
                  80                  85                  90

 Lys Thr Lys Arg Gly Gln Ala Ala Leu Asp Arg Leu Lys Val Phe
                  95                 100                 105

 Asp Gly Ile Pro Pro Pro Tyr Asp Lys Lys Lys Arg Met Val Val
                 110                 115                 120

 Pro Ala Ala Leu Lys Val Val Arg Leu Lys Pro Thr Arg Lys Phe
                 125                 130                 135

 Ala Tyr Leu Gly Arg Leu Ala His Glu Val Gly Trp Lys Tyr Gln
                 140                 145                 150

 Ala Val Thr Ala Thr Leu Glu Glu Lys Arg Lys Glu Lys Ala Lys
                 155                 160                 165

 Ile His Tyr Arg Lys Lys Lys Gln Leu Met Arg Leu Arg Lys Gln
                 170                 175                 180

 Ala Glu Lys Asn Val Glu Lys Lys Ile Asp Lys Tyr Thr Glu Val
                 185                 190                 195

 Leu Lys Thr His Gly Leu Leu Val
                 200

<210> 2673
<211> 4436
<212> DNA
<213> Homo sapien

<400> 2673
 cccccttgtc attaatacat taaaaagatt caatctttac cctgaggtaa 50

 ttttggccag ttggtaccgg atttatacca aaataatgga cttgattggt 100

 attcaaacca agatatgttg gacggttacc agaggagaag gactcagtcc 150

 tattgaaagc tgtgaaggat tgggagatcc tgcttgcttt tatgttgctg 200

 taatttttat tttaaatgga ctaatgatgg cattattctt catatatggc 250

 acatatttaa gtggcagccg attaggaggc ctggttacag tgttgtgctt 300

 ctttttcaat catggagagt gtacccgtgt aatgtggaca ccacctctcc 350

 gtgaaagctt ctcatatcca tttcttgttc ttcagatgtt gctagtgact 400

 catattctca gggctacaaa actttataga ggaagcttga ttgcactctg 450

 catttccaat gtatttttca tgcttccttg gcagtttgct cagtttgtac 500

 ttcttactca gattgcatca ttatttgcag tatatgttgt cgggtacatt 550

 gatatatgta aattacggaa gatcatttat atacacatga tttctcttgc 600

 actttgtttt gttttgatgt ttgggaactc aatgttatta acttcttatt 650

 atgcttcttc tttggtaatt atttggggta ttctggcaat gaaaccacat 700

 ttcctgaaaa taaatgtatc tgaacttagt ttatgggtta ttcaaggatg 750

 tttttggtta tttggaactg tcatacttaa atacttgaca tctaaaattt 800

 ttggtattgc agatgacgct catattggca acttactaac atcaaaattc 850

 tttagttata aggattttga tactttattg tatacctgtg cagcggagtt 900

 tgactttatg gaaaaagaga ctccactgag atacacaaag acattattgc 950

 ttccagttgt tcttgtagtg tttgttgcta ttgttagaaa gattattagt 1000

 gatatgtggg gtgtcttagc taaacaacag acacatgtaa gaaaacacca 1050

 gtttgatcat ggagagctgg tttaccatgc attgcaattg ttagcatata 1100

 cagcccttgg tattttaatt atgagactaa aactcttctt gacaccacac 1150

 atgtgtgtta tggcatcact gatctgctca agacagctat ttggatggct 1200

 cttttgcaaa gtacatcctg gtgctattgt gtttgctata ttagcagcaa 1250

 tgtcaataca aggttcagca aatctgcaaa cccagtggaa tattgtaggg 1300

 gagttcagca atttgcccca agaagaactt atagaatgga tcaaatatag 1350

 tactaaacca gatgcagtgt ttgcgggtgc catgcccacg atggcaagtg 1400

 ttaagctctc tgcacttcgg cccattgtga atcatccaca ttatgaagac 1450

 gcaggcttga gagccagaac aaaaatagta tactcaatgt atagtcggaa 1500

 agcagccgaa gaagtgaagc gagaactgat aaagttaaaa gtgaactatt 1550

 acattctaga agagtcatgg tgtgtaagaa gatccaagcc tggttgcagt 1600

 atgcctgaaa tttgggatgt agaagatcct gccaatgctg ggaaaactcc 1650

 cttatgtaac ctcttggtga aggattccaa acctcacttc accactgtat 1700

 tccagaacag tgtttacaaa gtcctagaag ttgtaaaaga atgactgcta 1750

 catgacctgc tgcctacgga gaactacatc tgtaatggtt ttaatgtttt 1800

 gctaagtcat gtgttgttca tatcccaaaa acttttatag gtaactgttt 1850

 tcaaatagaa aacgttttat ttggtcaatt tgaatgtcat tctaattata 1900

 aaaatgactt acacctttat caattggtta ctatttcaat gcacccttta 1950

 aaatttgcta tgcaaatgag tatatgcttg tacttgactt taatatttgt 2000

 gctaaagtga gcaaagctac ctgtataaag aaaacacagt gggttgtgac 2050

 aaggatgaca tgaaaataca ggacaattct gacaatgtag gggctgattt 2100

 tatagtgtaa gaactattaa tgccccttgc ttcttttttc tgcctcttgc 2150

 tcttgtcttt tggacatttc agtgattgta agttcttcgg tcatgtcagc 2200

 ccctgtcatc aacttgagtt acagtagatg gggcagacat ggagtgtttg 2250

 ctatataaaa ctatctgttt gttttacttc cttgtgcgct ttttgttctc 2300

 tgttctcttg ttaatgaagc ttttcctgcc cattattaat ccaaactctt 2350

 ggaccttgtg gttaggaaat tcccttaact tccagccata tggcattatc 2400

 gtgtctcttt ctctctctct cttgctctct ctcttctcct cttccccata 2450

 ttttctgtca aataagtact gtttactcat ttagttgctt atcaagtact 2500

 tattcttggt tttaaaaaaa attaatggta actgtatttt tctcattttt 2550

 agcattattc aaatgtttat attttaatac ctttaaacca ctttaaagtt 2600

 ttttcatgtt taattatagt tttaagaaaa actattttga acaaccccaa 2650

 atatagtgca tctagaaact aatgtatatt tgattagaca tcatttatag 2700

 tggaacagta gactgtagta catggtaatt tttcttttac tattaagata 2750

 caataaaaca tgactaattt tgctgtcaaa aatgtaaaga ataatgataa 2800

 atggagtttt ttatatttta cttttaagat tgcctgtctt taataagaca 2850

 aagccttaag ccttatgtta taattttggt tctaaaaacc atcatttcag 2900

 tataaggaat aagtatattt cgtcctcctc tttagttttt ttcttcctat 2950

 ttatttttat tttgaaaaat ttctacacct tctttgaatt ccttgtatga 3000

 atttttgttt cttagaagtt aatttgtgtg aaatgagatt cttcaaaacg 3050

 atgaaacctc atagctctga gaaaaggttt tagggtttta aattctaagc 3100

 aaagcgtgac tatggctgac agactacaca tttaattata cagcttctct 3150

 ttcttaacca caggcagatt aacctcattg tggattgtcc ttcagacctt 3200

 agtcctcagg catggtttct ggtgcccact cctggaagcc gctgttccct 3250

 ttctaccttc ttaccagagc ccaagggcag gcctggtccc ggggaagcag 3300

 cagcttgctg acataagtca gctgcaaagg ctgaggagtg tgccctcaga 3350

 gaagcaccgc cccccagtct tgtgccagcg cctagagccg cagctcccag 3400

 ggatgctcct tccctggagg cagcccagga gagggactct ggcagcgttc 3450

 ttcagatttg tggccactgt ttctcatttg ctggttgact gtttttattt 3500

 cttaggcttt tgctagtttt agaaaatagg gaagcagccc ttgatttgtg 3550

 gattaaaagc aacatttgag cgatgatgca caacagtcca ggaaaatggg 3600

 cggtggacac ttgaggctga ggatgggagt tgacatgagc agggagaggg 3650

 aggtgcgcgc tgcttatctg tgattgttgc tcacctgagt gtggctgatt 3700

 gtgtacatcc agcagttaca atttttaaaa attatacttt tacatttatt 3750

 ttatattttt ctcaccccca gtaatttcct tccaaagaag ttcacatgta 3800

 ataagtagaa attctgtata ggaaaaaagc attaaaaata ctattataac 3850

 tgcttcattt gctgggaacc attaaaagta atataaatta gctttttcca 3900

 gaaggatcct tttgtagcag tgtttatgaa tgtaaccccc agcaaaatat 3950

 ggctatatat taggggagcc agtttggagc agaggcctga aggtccctgc 4000

 tatgcagccg tggccacagc tcgcagccca agcactgtgg agcatccaca 4050

 cctttgatgg caatgcagat tggtagcagg ttccataggc gtacaaaaca 4100

 gtattaaagc tcagtgtttt gcatattgtt agcatttaca aatatttttg 4150

 ctttagtatg aggaaagtaa ggatgggcaa agaagcgatc aaaatagcta 4200

 ttgctacaac attttcgaaa acaaagttgg ggctgtattt ctttaaaaag 4250

 ataagcctct aaaaatgctt ggcaaaaaaa atatagtgtt aaaataggcc 4300

 agtgatatta atgagaaaat gaaagtatgt atcaggaata aagtgatatt 4350

 gcataggagt attgtatttt tatgaatttt atgccagttg tttacatgta 4400

 ctatatatgt taaattaaaa aaaatcatga gaaatg 4436

<210> 2674
<211> 580
<212> PRT
<213> Homo sapien

<400> 2674
 Pro Leu Val Ile Asn Thr Leu Lys Arg Phe Asn Leu Tyr Pro Glu
   1               5                  10                  15

 Val Ile Leu Ala Ser Trp Tyr Arg Ile Tyr Thr Lys Ile Met Asp
                  20                  25                  30

 Leu Ile Gly Ile Gln Thr Lys Ile Cys Trp Thr Val Thr Arg Gly
                  35                  40                  45

 Glu Gly Leu Ser Pro Ile Glu Ser Cys Glu Gly Leu Gly Asp Pro
                  50                  55                  60

 Ala Cys Phe Tyr Val Ala Val Ile Phe Ile Leu Asn Gly Leu Met
                  65                  70                  75

 Met Ala Leu Phe Phe Ile Tyr Gly Thr Tyr Leu Ser Gly Ser Arg
                  80                  85                  90

 Leu Gly Gly Leu Val Thr Val Leu Cys Phe Phe Phe Asn His Gly
                  95                 100                 105

 Glu Cys Thr Arg Val Met Trp Thr Pro Pro Leu Arg Glu Ser Phe
                 110                 115                 120

 Ser Tyr Pro Phe Leu Val Leu Gln Met Leu Leu Val Thr His Ile
                 125                 130                 135

 Leu Arg Ala Thr Lys Leu Tyr Arg Gly Ser Leu Ile Ala Leu Cys
                 140                 145                 150

 Ile Ser Asn Val Phe Phe Met Leu Pro Trp Gln Phe Ala Gln Phe
                 155                 160                 165

 Val Leu Leu Thr Gln Ile Ala Ser Leu Phe Ala Val Tyr Val Val
                 170                 175                 180

 Gly Tyr Ile Asp Ile Cys Lys Leu Arg Lys Ile Ile Tyr Ile His
                 185                 190                 195

 Met Ile Ser Leu Ala Leu Cys Phe Val Leu Met Phe Gly Asn Ser
                 200                 205                 210

 Met Leu Leu Thr Ser Tyr Tyr Ala Ser Ser Leu Val Ile Ile Trp
                 215                 220                 225

 Gly Ile Leu Ala Met Lys Pro His Phe Leu Lys Ile Asn Val Ser
                 230                 235                 240

 Glu Leu Ser Leu Trp Val Ile Gln Gly Cys Phe Trp Leu Phe Gly
                 245                 250                 255

 Thr Val Ile Leu Lys Tyr Leu Thr Ser Lys Ile Phe Gly Ile Ala
                 260                 265                 270

 Asp Asp Ala His Ile Gly Asn Leu Leu Thr Ser Lys Phe Phe Ser
                 275                 280                 285

 Tyr Lys Asp Phe Asp Thr Leu Leu Tyr Thr Cys Ala Ala Glu Phe
                 290                 295                 300

 Asp Phe Met Glu Lys Glu Thr Pro Leu Arg Tyr Thr Lys Thr Leu
                 305                 310                 315

 Leu Leu Pro Val Val Leu Val Val Phe Val Ala Ile Val Arg Lys
                 320                 325                 330

 Ile Ile Ser Asp Met Trp Gly Val Leu Ala Lys Gln Gln Thr His
                 335                 340                 345

 Val Arg Lys His Gln Phe Asp His Gly Glu Leu Val Tyr His Ala
                 350                 355                 360

 Leu Gln Leu Leu Ala Tyr Thr Ala Leu Gly Ile Leu Ile Met Arg
                 365                 370                 375

 Leu Lys Leu Phe Leu Thr Pro His Met Cys Val Met Ala Ser Leu
                 380                 385                 390

 Ile Cys Ser Arg Gln Leu Phe Gly Trp Leu Phe Cys Lys Val His
                 395                 400                 405

 Pro Gly Ala Ile Val Phe Ala Ile Leu Ala Ala Met Ser Ile Gln
                 410                 415                 420

 Gly Ser Ala Asn Leu Gln Thr Gln Trp Asn Ile Val Gly Glu Phe
                 425                 430                 435

 Ser Asn Leu Pro Gln Glu Glu Leu Ile Glu Trp Ile Lys Tyr Ser
                 440                 445                 450

 Thr Lys Pro Asp Ala Val Phe Ala Gly Ala Met Pro Thr Met Ala
                 455                 460                 465

 Ser Val Lys Leu Ser Ala Leu Arg Pro Ile Val Asn His Pro His
                 470                 475                 480

 Tyr Glu Asp Ala Gly Leu Arg Ala Arg Thr Lys Ile Val Tyr Ser
                 485                 490                 495

 Met Tyr Ser Arg Lys Ala Ala Glu Glu Val Lys Arg Glu Leu Ile
                 500                 505                 510

 Lys Leu Lys Val Asn Tyr Tyr Ile Leu Glu Glu Ser Trp Cys Val
                 515                 520                 525

 Arg Arg Ser Lys Pro Gly Cys Ser Met Pro Glu Ile Trp Asp Val
                 530                 535                 540

 Glu Asp Pro Ala Asn Ala Gly Lys Thr Pro Leu Cys Asn Leu Leu
                 545                 550                 555

 Val Lys Asp Ser Lys Pro His Phe Thr Thr Val Phe Gln Asn Ser
                 560                 565                 570

 Val Tyr Lys Val Leu Glu Val Val Lys Glu
                 575                 580

<210> 2675
<211> 4863
<212> DNA
<213> Homo sapien

<400> 2675
 ccacgcgtcc ggccagctgg agaggttcag cttggagaag gagagtcttc 50

 agcaggaagt aaggacgctg aagagcaaag tgggcgagct caacgagcag 100

 ctgggaatgc tcatggagac catccaagcc aaggacgagg tcatcatcaa 150

 gctcagcgag ggcgagggca acgggcctcc tcccaccgtg gcgcccagct 200

 ccccttcggt tgtgcctgtt gccagggacc agctggaact ggacaggctg 250

 aaagataatc tacaggggta caaaacccaa aacaaatttc taaataagga 300

 gattttggaa ctctcagctc tacgaagaaa tgcagaaagg agagagaggg 350

 atctgatggc aaagtattct agcctggaag ccaagctctg ccagatagaa 400

 agtaaatacc tgatattgct ccaagaaatg aagacaccag tgtgctcaga 450

 agaccagggg cccacccggg aggtcatagc ccagttgctg gaggatgctc 500

 tgcaggttga gagccaagag cagccggagc aagcatttgt taaacctcat 550

 cttgtcagtg aatatgatat ttatgggttc aggactgtac ctgaggatga 600

 tgaggaagag aaattggttg ccaaggtccg cgcgttggat ctgaagactc 650

 tctacctcac agaaaaccag gaagtctcca ctggggtcaa gtgggaaaac 700

 tattttgcaa gtacagtgaa cagggagatg atgtgctctc cagagttaaa 750

 aaacctcatc cgtgcgggca ttccccacga gcaccgttcc aaggtgtgga 800

 agtggtgtgt ggaccgtcac accaggaagt tcaaggacaa cactgagcct 850

 ggccacttcc agaccttgct gcagaaggcg ctggagaaac agaacccagc 900

 ctccaagcag attgagctgg acttgctgcg aactctgccc aacaacaaac 950

 attactcctg ccccacctca gaaggcatac agaagttacg caatgtcctc 1000

 ctcgccttct cctggcggaa tccagatatc ggctactgtc aaggcctaaa 1050

 caggttggtg gcagtggccc tcctgtacct ggaacaagaa gatgctttct 1100

 ggtgtctcgt taccatagtg gaagttttca tgcctcgaga ctattataca 1150

 aagactcttt taggatccca ggtggaccag cgggtgttca gagaccttat 1200

 gagtgagaag ctgcctcggt tgcatggcca ctttgaacag tacaaagtcg 1250

 actacactct catcactttc aactggtttc tggtggtatt tgtggatagt 1300

 gtcgttagtg acatcctctt taaaatatgg gactctttcc tttatgaagg 1350

 accaaaggtt attttccgtt ttgctctggc actttttaag tacaaggaag 1400

 aggagatttt gaaattgcaa gattcgatgt ctatatttaa gtatctccgc 1450

 tacttcactc gcactatcct tgatgctagg aagctgatca gtatctcctt 1500

 tggggacctg aaccctttcc ccctacgcca gatccggaac cgacgcgcct 1550

 accacttgga gaaagtccgg ctggagctga ccgagctgga ggccatccgt 1600

 gaggacttcc tgcgtgagcg ggacaccagc cctgacaagg gtgagctggt 1650

 cagtgacgag gaggaggata cctgagtggg ctcgggatgc tgctcttcct 1700

 tccttcacaa ccaaagtgtg cccaaagggt gaaagtgcac ttaaaagcca 1750

 gaatgtaacg tgtgtgtcct ctggggatct gctgggcaga tgtcccaagc 1800

 caggctgccc ttcctcattt cccactgtgc ggggggcagg ggtgggaggt 1850

 ctaatctgtt tacaaccatt tccgtgccat gcttttggtt acacgtatct 1900

 cagtcacgct ttctgcctgg ttggtggatc ctcaggctta ccagtggcta 1950

 tttgcaagag cctgtttcca gcctccgtca gcctgtcggt gctctgaccc 2000

 tctgaaacct tgctttgctg ggcatctccc catattctct ctcctgtaca 2050

 tagtgggcag tggtgtgtgg ttttgaatgg cagtgctata aaggatgcca 2100

 gctgtgcttt aggcacctgt aggccagagg gttgctgcct caggcataag 2150

 gttggtatga aaaggggctg ccttagaaaa gcaggcacat cccttgttca 2200

 gaaatggcca ctgtaggaaa gcctgtgaac ctcccaccag tggctttaag 2250

 ctgccagcca tgccccattt ctagaatagc ctttgctctt ccacacgcaa 2300

 cccttccatc agtgtcttcc agcctgcatg gggagggcct ggctgcccag 2350

 acacccaccc tcacttctca tggccagcct gtgtttgcag atcactgggc 2400

 tgctctgtcc ccagcttgcc ccgtgccagg catggctctg tgagattctg 2450

 tggaatgccc ttcttgactt gtggaaatca ttcaccaagt acgatgggat 2500

 gggattccaa gtaaacagtg gaccgtcata ttgcaaagca ggcccacgcc 2550

 tgggctggcc ttggttgagg ggatggagga atgttttcgg gggtgctttg 2600

 cagggcagtg gtgcagccgc agcgtgaacg ctcttggaca gctgaaaacc 2650

 atggcctcct tggggatggc cagtgctcct ggtgtctcca cctgcctggg 2700

 ttgtgcagga ggccggctgc cagtgcctgg ggctgggaaa cttttttgct 2750

 tggggcaggc ttgggtgagc tctcccagat gtgtgcccac cccaccactg 2800

 cctggaacat ccttgttctc tgccaggatg caggggcact gttgcctctg 2850

 acacagcagt ttctgggaac tcagaggact gcctttctga aggctgggga 2900

 gaggctttga gcaaggagct tgtttttgct taatcgctct agaccatccc 2950

 tgatgcgtag atgtgagagg atgttttctg gcacagtgtt atgaaaatac 3000

 aagataaatg atctcagtgg aatgtttcat attacccgaa aaaaactgga 3050

 aatcatcctt tgttgtgaac acactgagac taagaattga agcaatgcag 3100

 ttttaagaag tatttttcct attttttgct gtcaactttt tggcaatgcc 3150

 acggcaaagt tggtgtttca gcacatgcta gagtgagctc cggcttcgtg 3200

 tctttaacca actccactaa tgtttcactg ggtagacgga gctggcctct 3250

 atatttagcc agaagccttt gcctcttttc aggcatcaaa aatgggtttt 3300

 gtcattgtct ttgtctttga gagcagcagt ttgaggtctg actccttcag 3350

 ttgtcctgtg agctgggcgt tgcagtctgc tcgaatcaag tgttggaaac 3400

 cccccacccc tcagcccatc gtgaaacgac agctgtcagc ctggggggcg 3450

 gctgctgagg aggtgcagca ggaatggggc tgggccctga ggttttactt 3500

 tccgagccaa tggcccctgg aacatgccag cacacactgc catgtcctgg 3550

 ggctaagagc tgcctttagg gacaggctcg tgttgtccag tttgccctga 3600

 gagatgcacc tgaccagggg cccgtcgtgg ctgcaaccca cggtggtatg 3650

 ttagtgtttc caggcagttg tcagcagctg ccgggtagtg tgtgtgtgcg 3700

 acagcaggag agttcctgga ggaaagggac tggggacact ttctcagagg 3750

 ttctcctgcc tggaatcaag tgatgcgtgt ccagaaggca agagagggcg 3800

 gctccgcctg gttaaagttt gggaacggga cggagccaac tcctccttcc 3850

 aggactgtgg gccccactct tttgcgctaa cacttcccct ccctcgggtc 3900

 actgaggaaa gagctgctct gtcccctcca gtgccctgaa ggtccctggc 3950

 ctccactggc tgccatggca gggggccctt ctgacagggg ctgccccaag 4000

 ctgctgttcc tcctctgaac cttcacccca acacccagcc cgtggcccct 4050

 gcaaggggga ccctgccagc tgggaaaccc aaaggcctgt ccaaacgtgc 4100

 gcaccaggac cgaggggagc tccctcccaa cacctgctag gaattgccaa 4150

 cttttaaatg gatggggttt tttatgggtt gaacctctgt taatactttt 4200

 gtacactctc actacagttt atatttttat aggctatttt ctcaaggtgt 4250

 ttctagattc cacatatcta ttttatataa caagttatta tgttatgtgt 4300

 gtgactccct tgtgtgtatc tgtgccagcc tcagcctccg agttgctttt 4350

 ccctctggcc ctgactctca ctgactcacc gatgtgatgt gcaggcccac 4400

 ttcttacccc agatagcctc gggcgctgcc tgtagtcatg ctgacagctg 4450

 tacagtagcc gccaagactg ctgacagctg gagacggttc tggtttcaac 4500

 tacggtatat tgatatcgga agtattctag acagatcctc ggttgggttt 4550

 tctagctaca tgtttgtatt gcacagatcc ccacctgcca tcctatagtg 4600

 ttgtcttcct gtgtgttccg gggcttctgg gcagctgggc ctgcccgggg 4650

 aagtccttgc aggtgggagg ccatacagag acccactgtg tgccactgag 4700

 cgtcccactg ctgctgggca actggaggac tgcagggggc gccaggtgac 4750

 tctctccttt tatatcacag cagctcctgt gctgaccttc aagttacgtt 4800

 ttggaactgt aatactaaag gaagaaataa actactaatt tgtataataa 4850

 aaaaaaaaaa aaa 4863

<210> 2676
<211> 415
<212> PRT
<213> Homo sapien

<400> 2676
 Met Lys Thr Pro Val Cys Ser Glu Asp Gln Gly Pro Thr Arg Glu
   1               5                  10                  15

 Val Ile Ala Gln Leu Leu Glu Asp Ala Leu Gln Val Glu Ser Gln
                  20                  25                  30

 Glu Gln Pro Glu Gln Ala Phe Val Lys Pro His Leu Val Ser Glu
                  35                  40                  45

 Tyr Asp Ile Tyr Gly Phe Arg Thr Val Pro Glu Asp Asp Glu Glu
                  50                  55                  60

 Glu Lys Leu Val Ala Lys Val Arg Ala Leu Asp Leu Lys Thr Leu
                  65                  70                  75

 Tyr Leu Thr Glu Asn Gln Glu Val Ser Thr Gly Val Lys Trp Glu
                  80                  85                  90

 Asn Tyr Phe Ala Ser Thr Val Asn Arg Glu Met Met Cys Ser Pro
                  95                 100                 105

 Glu Leu Lys Asn Leu Ile Arg Ala Gly Ile Pro His Glu His Arg
                 110                 115                 120

 Ser Lys Val Trp Lys Trp Cys Val Asp Arg His Thr Arg Lys Phe
                 125                 130                 135

 Lys Asp Asn Thr Glu Pro Gly His Phe Gln Thr Leu Leu Gln Lys
                 140                 145                 150

 Ala Leu Glu Lys Gln Asn Pro Ala Ser Lys Gln Ile Glu Leu Asp
                 155                 160                 165

 Leu Leu Arg Thr Leu Pro Asn Asn Lys His Tyr Ser Cys Pro Thr
                 170                 175                 180

 Ser Glu Gly Ile Gln Lys Leu Arg Asn Val Leu Leu Ala Phe Ser
                 185                 190                 195

 Trp Arg Asn Pro Asp Ile Gly Tyr Cys Gln Gly Leu Asn Arg Leu
                 200                 205                 210

 Val Ala Val Ala Leu Leu Tyr Leu Glu Gln Glu Asp Ala Phe Trp
                 215                 220                 225

 Cys Leu Val Thr Ile Val Glu Val Phe Met Pro Arg Asp Tyr Tyr
                 230                 235                 240

 Thr Lys Thr Leu Leu Gly Ser Gln Val Asp Gln Arg Val Phe Arg
                 245                 250                 255

 Asp Leu Met Ser Glu Lys Leu Pro Arg Leu His Gly His Phe Glu
                 260                 265                 270

 Gln Tyr Lys Val Asp Tyr Thr Leu Ile Thr Phe Asn Trp Phe Leu
                 275                 280                 285

 Val Val Phe Val Asp Ser Val Val Ser Asp Ile Leu Phe Lys Ile
                 290                 295                 300

 Trp Asp Ser Phe Leu Tyr Glu Gly Pro Lys Val Ile Phe Arg Phe
                 305                 310                 315

 Ala Leu Ala Leu Phe Lys Tyr Lys Glu Glu Glu Ile Leu Lys Leu
                 320                 325                 330

 Gln Asp Ser Met Ser Ile Phe Lys Tyr Leu Arg Tyr Phe Thr Arg
                 335                 340                 345

 Thr Ile Leu Asp Ala Arg Lys Leu Ile Ser Ile Ser Phe Gly Asp
                 350                 355                 360

 Leu Asn Pro Phe Pro Leu Arg Gln Ile Arg Asn Arg Arg Ala Tyr
                 365                 370                 375

 His Leu Glu Lys Val Arg Leu Glu Leu Thr Glu Leu Glu Ala Ile
                 380                 385                 390

 Arg Glu Asp Phe Leu Arg Glu Arg Asp Thr Ser Pro Asp Lys Gly
                 395                 400                 405

 Glu Leu Val Ser Asp Glu Glu Glu Asp Thr
                 410                 415

<210> 2677
<211> 1345
<212> DNA
<213> Homo sapien

<400> 2677
 ggcgtaaacc actgcacgca gcctaccctc tgccttttta agatgatgta 50

 tttatttaat ttttgccatc attggtgctt caccttcctg cgaaggaaat 100

 tccagagcct gtatttaagc tacctaggct tttacactcc ctttattgcc 150

 tttccaaata gtatctcatt tggtgtactc tagtgtccta tacctcttgg 200

 aaacgaaaga gggcccaacc tacaactaag aagggacaaa ccttgaacta 250

 agtaagacct tacacaccca gaaagaacac tgggccctcc ttcttcaggg 300

 acaatgcagt agccacttgg cttgtggaat ttactgaagg ctatttcctg 350

 taacttgcta gttaacttag ttttgtattt caggcagagg tgcgctctgt 400

 aatgttgggc ctttgacttc acagtactgg agagctgttc acacagatgt 450

 ttagaccttt ctctctctct ctcttttctt ctttctcaac aactctttca 500

 cagaggcagt cattttgaaa ggttgaaata tttggccttt accaaagagc 550

 tttttttttc cttaagcaaa atcctttcag aaagaaacaa atggggaagg 600

 gcagattaag aatgcatatg tcccaatcca cttctatagg agtttaatca 650

 tattcacatg agtaaaatga tggaagaact ctttaaggta atcctttggg 700

 ataaaggatc ctgggaagtt ctctcaggta aagaaagctt acagcagatt 750

 tgtaatatat gtctggagag ctatttataa gaaatttaag aggattgttt 800

 tgttttcctt tattaaagat ttaagccttt ttactttgca aaaagaaaac 850

 tacaaaagtt ttatagatat aactttgcta attttttaaa cttttctgaa 900

 acgattagct gtagccaaat tatgtggtta cgttttgcta cattagaatt 950

 tgaaaatgca atatgtgtgg taaatctact gtttgaaatt tataatggtc 1000

 tctgatatga ttcgaatttt ggtaactttt gaaagttatt ttcccccttt 1050

 agtcatggat ttctatttgt tttttaatgt taatttttct agaaagcatc 1100

 tgaattgact aggcttttcc tatataaaaa actcaaaact tgttaactct 1150

 gtactttaat aaaatttaaa attaaaactg tgttgttttt ttctcttctg 1200

 ctagatacat atataattaa agtactcaag ttagttgttt tgcagagatg 1250

 ttgccttcag atgttaatca ggtctctcaa gtttcatgga gtctatgctg 1300

 atcctttaat tgacaaataa aagatatata tctgtggtgt gcaac 1345

<210> 2678
<211> 60
<212> PRT
<213> Homo sapien

<400> 2678
 Gly Val Asn His Cys Thr Gln Pro Thr Leu Cys Leu Phe Lys Met
   1               5                  10                  15

 Met Tyr Leu Phe Asn Phe Cys His His Trp Cys Phe Thr Phe Leu
                  20                  25                  30

 Arg Arg Lys Phe Gln Ser Leu Tyr Leu Ser Tyr Leu Gly Phe Tyr
                  35                  40                  45

 Thr Pro Phe Ile Ala Phe Pro Asn Ser Ile Ser Phe Gly Val Leu
                  50                  55                  60

<210> 2679
<211> 7912
<212> DNA
<213> Homo sapien

<400> 2679
 ggaaattatt agatgaattg tcagacccag aatcttcaaa acttattgga 50

 gaagtgttta atattgtgag ccaacagtct actgctcgac ctggctgcat 100

 tattgaactc gacgcaataa ccaaccaatg tggctcaaat acacagttgc 150

 ttcatgtgtt tcaagaagac ttcattatag gatataaacc acataaggaa 200

 gatatggaga aaaaggaaac agaaatattt tttcagccat cacaaggata 250

 ccgcccacca ccattttcag aaaagttctt tctagtagta attgagaagg 300

 acagcaataa taactctatt ctgcatatgt ggcaccttca tcttaaatct 350

 gtacaagcat gtttagctaa agcttcagaa ggggcttcct ctgagagtct 400

 actttcagtc cctggacaga agaatgtaga ttcttctcca gaaacctctc 450

 ctagtgtgag ccccatgcca cattcttcat caattgccaa tcttcaaact 500

 gccagtaaac ttattctgag ttctagactg gtgtatagcc aaccccttga 550

 tctcccagaa tcagttgaag taataagagc aacgccttca gcaggccatc 600

 tgagttcttc ttcaatttat ccagtgtgcc ttgcacctta tttagtggtt 650

 acaacttgtt ctgacaataa agtacgcttc tggaaatgtt gtatggaagc 700

 caacccagag tgtaataaaa gtgatgagaa agaaatttat cattggaaga 750

 gatggccttt gatgaatgat gaaggagaag ataatagcag tacagtgagc 800

 attgtgggaa gaccagttgc tgttagctgt tcatacacag gtcgccttgc 850

 agtggcttat aagcagccta tccaccataa tggttttgtt tctaaagaat 900

 tttccatgca tgtttgtata tttgaatgtg aatctacagg aggatcagag 950

 tgggttttag aacaaacaat tcatcttgat gatttggtta aggttgggag 1000

 tgtacttgat tcaagggtca gcgtcgacag taatctgttt gtgtatagca 1050

 agtcagatgc actcttgagc aaggatagat atcttattcc gaatatcaaa 1100

 catttagtac atttggactg ggtatcaaaa gaagatggct cccacattct 1150

 tacagtggga gtcggtgcga atatcttcat gtatggaagg ctttcaggaa 1200

 ttgtgactga gcaaaccaac agtaaggatg gagtagctgt catcacttta 1250

 ccactaggtg gtagtatcaa gcaaggagtt aagtcaagat gggttcttct 1300

 tagatctata gacttggtat cttctgttga tggtactcct tcactgcctg 1350

 tttctctctc ttgggtaaga gatgggatat tggtggtagg aatggattgt 1400

 gaaatgcatg tatatgcaca gtggaagcat gctgtcaaat ttggagacac 1450

 tgaagctgat agtcctaatg cagaagaggc agcaatgcaa gatcattcga 1500

 cctttaaatc taatatgctg gcaagaaaaa gtgttgttga aggaacagct 1550

 atttctgatg atgttttttg ttcaccaact gtaattcaag atggtggctt 1600

 atttgaggct gcacatgtac tttcccctac tcttccacaa tatcatccaa 1650

 ctcagctgtt agaattgatg gatttaggga aagtgcgaag ggctaaagcc 1700

 attctctctc atttagtaaa atgtattgca ggtgaagtag caatagttag 1750

 agatcctgat gctggagaag gaactaagcg acatctctct cgaactatta 1800

 gtgtaagtgg cagtacagca aaggaaacag tcaccgtagg aaaagatggt 1850

 actcgagatt atactgagat agattctatc cctccactac cactatatgc 1900

 attacttgct gcagatcaag atacatccta cagaatttca gaagaaagta 1950

 caaagatacc acagagctat gaagatcaga cagtaagtca accagaggat 2000

 cagtattcag agctgtttca aatccaggat ataccaacgg atgatattga 2050

 tttagagcct gaaaagagag aaaacaaatc aaaagtaata aatctttctc 2100

 aatatggacc agcttacttt ggccaagaac atgcaagggt actttcaagt 2150

 catcttatgc actcaagtct accaggcctt acccgtttgg agcagatgtt 2200

 ccttgtagct ttggctgata cagtggctac tactagtact gagcttgatg 2250

 aaagcagaga taagagttgc tcaggaagag atacattaga tgagtgtggt 2300

 ttgagatact tgttagctat gcgcctacac acatgccttt tgacatcgct 2350

 gcctccttta taccgagtgc agctacttca tcaaggtgtc tctacatgcc 2400

 attttgcctg ggcttttcat tctgaggctg aagaagaact gattaatatg 2450

 attccagcaa ttcagagagg ggacccccag tggtctgaat taagagctat 2500

 gggcataggg tggtgggtga ggaacattaa cacgcttcga agatgcattg 2550

 aaaaggttgc caaagcttct tttcaaagga acaatgatgc cttagatgct 2600

 gcactattct acctttcaat gaagaagaaa gcagtagtgt ggggtctgtt 2650

 taggtcacag catgatgaaa aaatgacaac atttttcagc cacaacttta 2700

 atgaagatag atggcgaaaa gctgctttga aaaatgcttt ttccttactt 2750

 ggaaaacaac gctttgaaca atcggctgct tttttcttgc tagctggttc 2800

 attgaaagat gccatagagg tatgtcttga aaaaatggaa gatattcagc 2850

 tagccatggt tattgcccgt ttatatgaat ctgaatttga gacttcatcc 2900

 acttatatat ccatcctaaa tcagaagatt ttgggttgcc aaaaggatgg 2950

 ctcaggattc agttgcaaaa gattacatcc tgatcctttc ctgcgtagtc 3000

 ttgcctattg ggtaatgaaa gattacaccc gagccttgga cacattactg 3050

 gaacaaacac caaaggagga tgatgaacat caagttatca tcaagtcttg 3100

 taacccggtg gcatttagtt tttataacta ccttcgaact catcctttgc 3150

 tcattcgaag aaatcttgcc tcccctgaag gaactttggc aaccttaggt 3200

 ctcaaaactg agaagaactt tgttgataaa attaacctca tagaaagaaa 3250

 attattcttt accactgcaa atgctcattt taaagttgga tgccctgttt 3300

 tagccttgga ggtactctcc aaaattccaa aagtaaccaa aacatctgcc 3350

 ttatctgcaa aaaaagatca gcctgacttc atttctcaca ggatggatga 3400

 tgtaccttca cattcaaaag ctctgagtga tggcaatgga agttctggca 3450

 ttgaatggtc aaatgtaact tcatcacagt atgactggag tcagccaata 3500

 gtaaaagttg atgaggaacc tcttaatctt gattggggtg aagatcacga 3550

 cagtgcctta gatgaagagg aagacgatgc tgttggttta gtgatgaaaa 3600

 gtacagatgc cagggaaaaa gataaacaat cagatcagaa ggcctcagac 3650

 cctaacatgt tattaacacc tcaggaagag gatgatcctg aaggtgatac 3700

 tgaagttgat gtgattgctg aacaactaaa attcagagct tgtttaaaga 3750

 tccttatgac tgaattaaga acattggcta caggttatga agtagatgga 3800

 ggaaaactca gatttcaact ctataactgg cttgaaaagg aaattgctgc 3850

 cttgcatgag atatgtaatc atgaatcagt tattaaagag tattccagta 3900

 agacatattc caaagtagag agtgatctgc tggatcagga agaaatggta 3950

 gacaaaccag atattggttc ctatgagcgc catcaaatag aaagaagaag 4000

 attgcaggcc aaacgagagc atgcagaaag acgaaagtcg tggttgcaga 4050

 aaaaccaaga tctcctgaga gtatttctca gctactgtag ccttcatggg 4100

 gcccaaggtg gtggtttggc ttcagtaagg atggaactca aatttttgct 4150

 acaagaatca caacaggaaa ctacagtaaa gcagctccag tctccactac 4200

 cactgcctac caccctacct ctgctttcag caagtattgc gtcaacaaaa 4250

 acagtcatag ctaatcctgt attgtactta aataatcaca tccatgatat 4300

 actttatact attgttcaga tgaaaacacc acctcatccc agtattgaag 4350

 atgtgaaggt gcacacactt cattcactag cagcatcact ttctgcatca 4400

 atttaccaag cattatgtga cagtcatagc tacagcagtc aaacagaagg 4450

 aaatcagttt acaggaatgg cttatcaagg acttctttta agtgatcgta 4500

 gaagactaag gacagaaagc attgaagaac acgcaacacc aaattcatct 4550

 cctgctcaat ggcctggtgt gagctcactt attaatcttt tgagttcagc 4600

 ccaagatgaa gaccagccaa aactgaacat tttgctatgt gaagctgttg 4650

 ttgctgttta cttaagttta ttgatacatg ctcttgccac aaattcctcc 4700

 agtgaattat ttcggcttgc agcccaccca ttaaataatc gaatgtgggc 4750

 tgctgttttt ggaggcggtg taaaacttgt tgtgaaacct cgaagacaat 4800

 cagaaaatat ttcagcacct cctgtccttt ctgaagacat agataaacac 4850

 cgtaggagat ttaacatgag aatgctcgtc cctggaaggc ctgtaaaaga 4900

 tgctacccca ccaccggtgc ctgcagaaag accatcttac aaagaaaaat 4950

 ttattcctcc cgaacttagt atgtgggatt attttgttgc aaagccattt 5000

 cttcctttgt ctgatagtgg tgttatatat gattctgatg aaagcattca 5050

 tagtgatgaa gaagatgatg cctttttttc agatacacaa atacaggagc 5100

 accaagatcc aaattcctat agctgggctc ttctacattt gacaatggtt 5150

 aaactagcac ttcacaatgt caagaatttc tttcctattg ctggactgga 5200

 attctctgag ctgcctgtaa catcaccatt aggtattgct gtgattaaaa 5250

 acttggagaa ctgggaacag atcttgcaag agaaaatgga tcagtttgaa 5300

 ggtccacccc ctaactatat caacacatat ccaactgacc tttcagtggg 5350

 agctggacca gctattcttc gaaataaagc aatgctagaa cctgaaaata 5400

 ccccattcaa gtcccgggat tcttctgcat ttccagtcaa acgactttgg 5450

 catttccttg ttaaacaaga ggtccttcaa gagacattta ttagatatat 5500

 tttcactaag aaaagaaagc agagtgaggt tgaagctgat ctgggctatc 5550

 caggtggaaa ggcgaaagtc atccataagg aatctgatat gatcatggca 5600

 ttttctgtta ataaggcaaa ttgtaatgaa attgttttgg cttcaacaca 5650

 tgatgttcaa gaacttgatg ttacttctct actggcctgt cagtcataca 5700

 tatggatcgg agaagaatat gacagagaat ccaaaagttc agatgatgtt 5750

 gattatcgtg gttccactac aactctttat caacccagtg caacatccta 5800

 ttcagcaagt caggtgcatc caccttcatc tctgccatgg ctgggcactg 5850

 gacagactag cactggagct agtgtgctta tgaaaaggaa tctacataat 5900

 gttaagagaa tgacttcaca cccagtccat caatactatc ttacaggtgc 5950

 tcaggacggc agtgtacgaa tgtttgaatg gacgcggcct cagcaacttg 6000

 tctgctttcg tcaagctggc aatgcaagag ttactagatt atattttaat 6050

 tcacaaggca acaagtgtgg tgttgcggat ggagagggtt ttctgagtat 6100

 ctggcaagtt aaccaaactg catcaaatcc taaaccttat atgagttggc 6150

 agtgccacag taaagccaca agtgactttg catttattac ctcttcaagt 6200

 ctagttgcca catctggaca ctccaatgac aatagaaatg tttgcctctg 6250

 ggacacatta atatcacccg gaaacagcct cattcatggt ttcacgtgcc 6300

 acgatcatgg tgccacggta ctgcagtatg cacccaaaca gcaactccta 6350

 atctcggggg gtaggaaagg acacgtctgc atttttgaca tcaggcaaag 6400

 gcagctcatt cacacgttcc aggcccatga ctcagctatt aaggctctgg 6450

 ccttggatcc ctatgaggaa tattttacca caggttcagc agaaggtaac 6500

 ataaaggttt ggagattgac aggccatggc ctaattcatt catttaaaag 6550

 tgaacatgct aagcagtcca tatttcgaaa cattggggct ggagtcatgc 6600

 agattgacat catccagggc aatcggctct tctcctgtgg tgcagatggc 6650

 acgctgaaaa ccagggtttt gcccaatgct tttaacatcc ctaacagaat 6700

 tcttgacatt ctataaagat tggggtttta tttttatata catttcagtt 6750

 aaaaggcaca ctacagtcat cactaggcaa ttctgctttc taagcagttg 6800

 tattgaaaac agagaatctc tgtgtagaat ttgaatatga cccaagctga 6850

 gtattatcta aacaggttgg tggaatgaat gcgcatgtac cttattatgc 6900

 tgacatacta aaaaaaataa aacctagtat tgtatgaagg atagctattc 6950

 tttacagcat ttagcaaacc tgattcagaa aacatttgag attagcaaat 7000

 tagtaacttg aaataatgaa aaggacgttt ataccaaatt aaggaagaaa 7050

 atgttgctga tttgggtttt tcttcctgtt cttaccactg actgaagcat 7100

 gcctgcagtc tcctcctctg ttgaatgaag gataatcata aggtgtttgt 7150

 taggagcgct agaccacctg gaaaactttc ttagctgtgg agcagtgcgc 7200

 agtgaccagt tctctgctgt gagaggccgt ttccattctt tcctgctgaa 7250

 tatttttcct gttagtgttt atactgagct agtactgtaa cttgcaaatg 7300

 agtgcaaatt taaatgcaat gttttactca caatttgcac attcacattt 7350

 tttggactgc tagtttttct atttaaatat ttgccttcat gttaggaatg 7400

 tactatgtga acatgacata tttgtagtta accaaacaca ccttcttagt 7450

 ccagtttagt actttttctt ttcgtgtatt caaggttaaa cacccaaaca 7500

 tttaaggata tgttgaaact acaccaatag agcatttcat atcataatta 7550

 aaatgaatgt taggcttctt gtggccagtt aatagttgat gagattggtg 7600

 acattattta ttgccacagc ctattgtata aactatgcag agttaaatat 7650

 ttgcttgtaa aatattagcc aatgttgtca ttattttgat gtatttcctt 7700

 ggttatgacc aaaaatatgt tgagatactg aaactaatgt ctgtgtgttt 7750

 aaatgtttac cagcaaattg tcttatcatg ttaatgagaa tgttcaatgc 7800

 ctgtgtggta aatagtaaat acaatggcat aaaagtaact ttctctgaag 7850

 atgtgatgtt caggctgtga aatatatatg taaaagaaaa ataaatgtta 7900

 tttgttagag tt 7912

<210> 2680
<211> 4403
<212> DNA
<213> Homo sapien

<400> 2680
 gtttgatatc tacactcagt attgcaacaa ttaccccaac tccgtggccg 50

 ccctgacgga atgcatgcgg gacaagcagc aggccaagtt ctttcgggac 100

 cggcaggagc tgctacagca ctcgctgccc ttgggctcct acctgctgaa 150

 gccagtccag cgcatcctca agtaccacct gctgctccag gaaattgcca 200

 agcattttga tgaagaagag gatggctttg aggtggtgga ggatgccatt 250

 gacaccatga cctgtgtggc ctggtacatc aacgacatga agaggaggca 300

 tgagcacgcg gtccggctcc aggagattca gtcactcctc atcaactgga 350

 aggggcccga cctgaccacc tacggggagc ttgtcctgga gggcacattc 400

 cgcgtgcatc gcgtgcgcaa tgaaaggacc tttttcctct ttgacaaaac 450

 actgcttatc accaagaagc ggggcgatca ctttgtctac aagggcaaca 500

 tcccggtaac caggccctgc cccatctcct ctgccatctt ctctccttcc 550

 caaaggatct gggctcccct tcttgtctgc ttcttggggc tccagcacca 600

 cccttctgag atcaccctcc ctgcttcccc aggctgtcaa ccttgtgctt 650

 gactgtcctt tccctctgcc cctagtgctc ctccctgatg ctgatcgaaa 700

 gcaccagaga ctccctgtgc ttcactgtca cccactacaa gcacagcaag 750

 cagcagtaca gcatccaggc caagacagtg gaggagaaac ggaactggac 800

 tcaccacatc aagaggctca tcctagagaa ccaccatgcc accattcccc 850

 agaaggccaa ggaagccatc ttggaaatgg attcctatta tcccaatcgg 900

 taccgctgca gcccagagcg gctgaagaag gcttggtcct cccaggatga 950

 ggtgtccacc aatgtgcgcc aggggcgccg gcaatctgag ccaaccaaac 1000

 acctgctcag gcaactcaac gagaaaggtg agtgtgtgag gtggccagcc 1050

 attcccagtg agcgggggag gaggagggag gaggggaagc agccgacaac 1100

 ctggggtgtg acctgagggt ggaggattgt cagaatagtg tagagggaac 1150

 tctgcctcca ttccccccag aagagggcct cgcccctggc tggctgagga 1200

 gaggggctgg agctctcccc catgcacagg cctcatgccc tttcctccgg 1250

 aaacaatgag agccgagcaa caggcacaga cctgcgctgc tctgtggccc 1300

 ctgggcccct gctctgtcag tcattctttt gaaagcccag gagactaggt 1350

 gagggttctg ggagcaggag cccccagtga ggacttcccc agggagctgt 1400

 ccagaggtct ttttcctgct tactgatctc ttcccctccc ctcccctgcc 1450

 cctcgcccgt gtgctggggg acccggtggt gatgtctgca gcccgagcag 1500

 caggaatgaa gggaaagggg cgcagggagt ctgaaagctc caggagcagc 1550

 agaaggccca gtggccggtc tccaaccagt actgagaagc gcatgagctt 1600

 cgagtccatt tcttccctgc cagaggttga gccggaccct gaggctggga 1650

 gtgagcaaga ggtattttct gctgtggaag ggcccagtgc cgaggagacg 1700

 ccttcagaca cagaatctcc agaagtcctg gagacacagc ttgatgccca 1750

 ccagggcctt ctggggatgg accccccagg tgacatggtg gacttcgtgg 1800

 cagctgagag cactgaggac cttaaggccc tgagcagcga ggaggaagaa 1850

 gaaatgggag gtgccgccca ggagcctgag agccttctgc caccctctgt 1900

 gctggaccag gccagcgtca ttgcggagcg atttgtcagc agcttctctc 1950

 ggcggagcag cgtggcacag gaggacagca agtccagtgg ctttgggagc 2000

 ccgcggctgg tcagccggag cagcagcgtg ctcagcctgg agggcagcga 2050

 gaagggcctg gcccggcatg gcagtgccac agactccctc agctgtcagc 2100

 tctccccaga agtggacatc agtgtggggg tggccacaga ggacagccct 2150

 tctgtcaatg ggatggagcc cccaagccca ggctgcccag tggagcctga 2200

 ccggtcttcc tgcaagaaga aggaatcagc actctccacc cgagaccggc 2250

 tgttgctaga caagattaag agctattatg aaaatgcaga acaccatgat 2300

 gcaggcttca gcgtccgtcg ccgggagagc ctctcctaca tccccaaagg 2350

 actggtaaga aactccatct ccaggttcaa cagccttccc cggccagacc 2400

 cagagccagt acctccagtg gggagcaaga gacaggtggg ctcccggccg 2450

 acttcgtggg ccctgtttga gctcccagga ccaagccagg cagtcaaagg 2500

 ggacccacct cccatctcag atgctgagtt ccgcccatct tcagaaattg 2550

 tgaagatctg ggagggaatg gagtcttccg gagggagccc tgggaagggg 2600

 ccaggccagg gccaggccaa tggctttgac ctgcatgagc cactcttcat 2650

 cctggaggag catgagctgg gagccatcac agaggagtcg gccactgcct 2700

 ccccggaaag ctcctctccc actgaggggc gcagcccggc ccacctggcc 2750

 cgggagctga aagagctggt gaaggagctg agcagcagta cccaggggga 2800

 gctggtggcc ccactgcacc cccgcatcgt gcagctctcc cacgtaatgg 2850

 acagccacgt gagcgagcgc gtcaagaaca aggtctacca gctggcccgc 2900

 cagtacagcc tccggatcaa gagcaacaag ccagtgatgg ccaggccacc 2950

 actgcagtgg gaaaaggtgg cccctgagag ggatgggaag agccccactg 3000

 tgccctgtct acaggaagag gctggagagc cattaggtgg caaaggtaag 3050

 aggaagccgg tgctgtctct atttgactat gagcagctga tggcccagga 3100

 gcacagccct cccaagccct cctcggctgg ggagatgtca ccacagcgtt 3150

 tcttcttcaa cccgtctgct gtcagccaga ggaccacctc gcctgggggc 3200

 cggccctccg cccggagccc cctcagcccc acagagacct tcagctggcc 3250

 cgacgtccgt gagctctgct ccaagtatgc ctcccgcgat gaggcacgcc 3300

 gagcaggggg cggccggccc cgcggcccac ccgtcaacag gagccactcg 3350

 gtgccggaga acatggtaga gccacctctg tcgggcaggg tgggccgctg 3400

 ccgcagcctg agcaccaaga ggggccgggg aggcggagag gctgcccaat 3450

 cccctgggcc tctgccccag agcaagccgg atggaggcga gaccctgtat 3500

 gtcactgcag acctcaccct ggaggacaac cggcgggtga ttgtcatgga 3550

 gaagggaccc cttcccagcc ccactgcagg gctggaggag agcagtggcc 3600

 agggaccaag ctcaccggtg gccctgctgg ggcaggttca ggacttccag 3650

 cagtctgcag agtgccagcc gaaggaagag ggttccaggg acccggcaga 3700

 cccgagccag cagggcagag tgagaaacct tagagagaag ttccaggcct 3750

 tgaactctgt cggttgatgc tgactcctgg gggagggagg agtcatgttg 3800

 gaggttgggg aagaacctgg gcatccttcc cctcaagcct gggctcatgg 3850

 agcccctgcc cagggccctc aggtgggcgg aaagtccatc ccctccgccc 3900

 ttcaggaagg atgctcccgt gtgcaggggt ctcctgcctg tgccatccac 3950

 tggggctcga gacaatttcc cactcacctg tgaggccggt gtggctgctt 4000

 cccttgtaaa tagttgttct ctggtaagaa gccaaatatt taagctcact 4050

 tattcccaga gagaggaagc tctgctcagg cctccagcgt tggctggcca 4100

 tggccacagc cagatggagg agcccatccc caggagactc aggcagtggc 4150

 ctggagaggc tttgttctgt aacggtgcct tttcttaggg tccaggcagg 4200

 aatgaagcca ataatttatt gctttccatt ctgtggtatg atgtgcgtgt 4250

 gcgtgagtgt gtggcccctg tttattcccc tcctgtcaag aatgaagtgg 4300

 attcagttca ggtacttttg agggttgttg tgctgaccct gtggttgtcg 4350

 ctgatgtaca cacatttcat tatttgccaa tggtgcaata accactgctg 4400

 acc 4403

<210> 2681
<211> 804
<212> PRT
<213> Homo sapien

<400> 2681
 Gly Phe Trp Glu Gln Glu Pro Pro Val Arg Thr Ser Pro Gly Ser
   1               5                  10                  15

 Cys Pro Glu Val Phe Phe Leu Leu Thr Asp Leu Phe Pro Ser Pro
                  20                  25                  30

 Pro Leu Pro Leu Ala Arg Val Leu Gly Asp Pro Val Val Met Ser
                  35                  40                  45

 Ala Ala Arg Ala Ala Gly Met Lys Gly Lys Gly Arg Arg Glu Ser
                  50                  55                  60

 Glu Ser Ser Arg Ser Ser Arg Arg Pro Ser Gly Arg Ser Pro Thr
                  65                  70                  75

 Ser Thr Glu Lys Arg Met Ser Phe Glu Ser Ile Ser Ser Leu Pro
                  80                  85                  90

 Glu Val Glu Pro Asp Pro Glu Ala Gly Ser Glu Gln Glu Val Phe
                  95                 100                 105

 Ser Ala Val Glu Gly Pro Ser Ala Glu Glu Thr Pro Ser Asp Thr
                 110                 115                 120

 Glu Ser Pro Glu Val Leu Glu Thr Gln Leu Asp Ala His Gln Gly
                 125                 130                 135

 Leu Leu Gly Met Asp Pro Pro Gly Asp Met Val Asp Phe Val Ala
                 140                 145                 150

 Ala Glu Ser Thr Glu Asp Leu Lys Ala Leu Ser Ser Glu Glu Glu
                 155                 160                 165

 Glu Glu Met Gly Gly Ala Ala Gln Glu Pro Glu Ser Leu Leu Pro
                 170                 175                 180

 Pro Ser Val Leu Asp Gln Ala Ser Val Ile Ala Glu Arg Phe Val
                 185                 190                 195

 Ser Ser Phe Ser Arg Arg Ser Ser Val Ala Gln Glu Asp Ser Lys
                 200                 205                 210

 Ser Ser Gly Phe Gly Ser Pro Arg Leu Val Ser Arg Ser Ser Ser
                 215                 220                 225

 Val Leu Ser Leu Glu Gly Ser Glu Lys Gly Leu Ala Arg His Gly
                 230                 235                 240

 Ser Ala Thr Asp Ser Leu Ser Cys Gln Leu Ser Pro Glu Val Asp
                 245                 250                 255

 Ile Ser Val Gly Val Ala Thr Glu Asp Ser Pro Ser Val Asn Gly
                 260                 265                 270

 Met Glu Pro Pro Ser Pro Gly Cys Pro Val Glu Pro Asp Arg Ser
                 275                 280                 285

 Ser Cys Lys Lys Lys Glu Ser Ala Leu Ser Thr Arg Asp Arg Leu
                 290                 295                 300

 Leu Leu Asp Lys Ile Lys Ser Tyr Tyr Glu Asn Ala Glu His His
                 305                 310                 315

 Asp Ala Gly Phe Ser Val Arg Arg Arg Glu Ser Leu Ser Tyr Ile
                 320                 325                 330

 Pro Lys Gly Leu Val Arg Asn Ser Ile Ser Arg Phe Asn Ser Leu
                 335                 340                 345

 Pro Arg Pro Asp Pro Glu Pro Val Pro Pro Val Gly Ser Lys Arg
                 350                 355                 360

 Gln Val Gly Ser Arg Pro Thr Ser Trp Ala Leu Phe Glu Leu Pro
                 365                 370                 375

 Gly Pro Ser Gln Ala Val Lys Gly Asp Pro Pro Pro Ile Ser Asp
                 380                 385                 390

 Ala Glu Phe Arg Pro Ser Ser Glu Ile Val Lys Ile Trp Glu Gly
                 395                 400                 405

 Met Glu Ser Ser Gly Gly Ser Pro Gly Lys Gly Pro Gly Gln Gly
                 410                 415                 420

 Gln Ala Asn Gly Phe Asp Leu His Glu Pro Leu Phe Ile Leu Glu
                 425                 430                 435

 Glu His Glu Leu Gly Ala Ile Thr Glu Glu Ser Ala Thr Ala Ser
                 440                 445                 450

 Pro Glu Ser Ser Ser Pro Thr Glu Gly Arg Ser Pro Ala His Leu
                 455                 460                 465

 Ala Arg Glu Leu Lys Glu Leu Val Lys Glu Leu Ser Ser Ser Thr
                 470                 475                 480

 Gln Gly Glu Leu Val Ala Pro Leu His Pro Arg Ile Val Gln Leu
                 485                 490                 495

 Ser His Val Met Asp Ser His Val Ser Glu Arg Val Lys Asn Lys
                 500                 505                 510

 Val Tyr Gln Leu Ala Arg Gln Tyr Ser Leu Arg Ile Lys Ser Asn
                 515                 520                 525

 Lys Pro Val Met Ala Arg Pro Pro Leu Gln Trp Glu Lys Val Ala
                 530                 535                 540

 Pro Glu Arg Asp Gly Lys Ser Pro Thr Val Pro Cys Leu Gln Glu
                 545                 550                 555

 Glu Ala Gly Glu Pro Leu Gly Gly Lys Gly Lys Arg Lys Pro Val
                 560                 565                 570

 Leu Ser Leu Phe Asp Tyr Glu Gln Leu Met Ala Gln Glu His Ser
                 575                 580                 585

 Pro Pro Lys Pro Ser Ser Ala Gly Glu Met Ser Pro Gln Arg Phe
                 590                 595                 600

 Phe Phe Asn Pro Ser Ala Val Ser Gln Arg Thr Thr Ser Pro Gly
                 605                 610                 615

 Gly Arg Pro Ser Ala Arg Ser Pro Leu Ser Pro Thr Glu Thr Phe
                 620                 625                 630

 Ser Trp Pro Asp Val Arg Glu Leu Cys Ser Lys Tyr Ala Ser Arg
                 635                 640                 645

 Asp Glu Ala Arg Arg Ala Gly Gly Gly Arg Pro Arg Gly Pro Pro
                 650                 655                 660

 Val Asn Arg Ser His Ser Val Pro Glu Asn Met Val Glu Pro Pro
                 665                 670                 675

 Leu Ser Gly Arg Val Gly Arg Cys Arg Ser Leu Ser Thr Lys Arg
                 680                 685                 690

 Gly Arg Gly Gly Gly Glu Ala Ala Gln Ser Pro Gly Pro Leu Pro
                 695                 700                 705

 Gln Ser Lys Pro Asp Gly Gly Glu Thr Leu Tyr Val Thr Ala Asp
                 710                 715                 720

 Leu Thr Leu Glu Asp Asn Arg Arg Val Ile Val Met Glu Lys Gly
                 725                 730                 735

 Pro Leu Pro Ser Pro Thr Ala Gly Leu Glu Glu Ser Ser Gly Gln
                 740                 745                 750

 Gly Pro Ser Ser Pro Val Ala Leu Leu Gly Gln Val Gln Asp Phe
                 755                 760                 765

 Gln Gln Ser Ala Glu Cys Gln Pro Lys Glu Glu Gly Ser Arg Asp
                 770                 775                 780

 Pro Ala Asp Pro Ser Gln Gln Gly Arg Val Arg Asn Leu Arg Glu
                 785                 790                 795

 Lys Phe Gln Ala Leu Asn Ser Val Gly
                 800

<210> 2682
<211> 2213
<212> DNA
<213> Homo sapien

<400> 2682
 gctctagaac tagtggatcc cccgggctgc aggaattctc taaagaagcc 50

 cctgggagca cagctcatca ccatggactg gacctggagg ttcctctttg 100

 tggtggcagc agctacaggt gtccagtccc aggtgcagct ggtgcagtct 150

 ggggctgagg tgaagaagcc tgggtcctcg gtgaaggtct cctgcaaggc 200

 ttctggaggc accttcagca gctatgctat cagctgggtg cgacaggccc 250

 ctggacaagg gcttgagtgg atgggaggga tcatccctat ctttggtaca 300

 gcaaactacg cacagaagtt ccagggcaga gtcacgatta ccgcggacga 350

 atccacgagc acagcctaca tggagctgag cagcctgaga tctgaggaca 400

 cggccgtgta ttactgtgcg aaaaccggga tcctggggcc gtatagcagt 450

 ggctggtacc cgaactcgga ctactactac tacggtatgg acgtctgggg 500

 ccaagggacc acggtcaccg tctcctcagg gagtgcatcc gccccaaccc 550

 ttttccccct cgtctcctgt gagaattccc cgtcggatac gagcagcgtg 600

 gccgttggct gcctcgcaca ggacttcctt cccgactcca tcactttctc 650

 ctggaaatac aagaacaact ctgacatcag cagcacccgg ggcttcccat 700

 cagtcctgag agggggcaag tacgcagcca cctcacaggt gctgctgcct 750

 tccaaggacg tcatgcaggg cacagacgaa cacgtggtgt gcaaagtcca 800

 gcaccccaac ggcaacaaag aaaagaacgt gcctcttcca gtgattgctg 850

 agctgcctcc caaagtgagc gtcttcgtcc caccccgcga cggcttcttc 900

 ggcaaccccc gcagcaagtc caagctcatc tgccaggcca cgggtttcag 950

 tccccggcag attcaggtgt cctggctgcg cgaggggaag caggtggggt 1000

 ctggcgtcac cacggaccag gtgcaggctg aggccaaaga gtctgggccc 1050

 acgacctaca aggtgaccag cacactgacc atcaaagaga gcgactggct 1100

 cagccagagc atgttcacct gccgcgtgga tcacaggggc ctgaccttcc 1150

 agcagaatgc gtcctccatg tgtgtccccg atcaagacac agccatccgg 1200

 gtcttcgcca tccccccatc ctttgccagc atcttcctca ccaagtccac 1250

 caagttgacc tgcctggtca cagacctgac cacctatgac agcgtgacca 1300

 tctcctggac ccgccagaat ggcgaagctg tgaaaaccca caccaacatc 1350

 tccgagagcc accccaatgc cactttcagc gccgtgggtg aggccagcat 1400

 ctgcgaggat gactggaatt ccggggagag gttcacgtgc accgtgaccc 1450

 acacagacct gccctcgcca ctgaagcaga ccatctcccg gcccaagggg 1500

 gtggccctgc acaggcccga tgtctacttg ctgccaccag cccgggagca 1550

 gctgaacctg cgggagtcgg ccaccatcac gtgcctggtg acgggcttct 1600

 ctcccgcgga cgtcttcgtg cagtggatgc agagggggca gcccttgtcc 1650

 ccggagaagt atgtgaccag cgccccaatg cctgagcccc aggccccagg 1700

 ccggtacttc gcccacagca tcctgaccgt gtccgaagag gaatggaaca 1750

 cgggggagac ctacacctgc gtggtggccc atgaggccct gcccaacagg 1800

 gtcaccgaga ggaccgtgga caagtccacc gagggggagg tgagcgccga 1850

 cgaggagggc tttgagaacc tgtgggccac cgcctccacc ttcatcgtcc 1900

 tcttcctcct gagcctcttc tacagtacca ccgtcacctt gttcaaggtg 1950

 aaatgatccc aacagaagaa catcggagac cagagagagg aactcaaagg 2000

 ggcgctgcct ccgggtctgg ggtcctggcc tgcgtggcct gttggcacgt 2050

 gtttctcttc ccgcccggcc tccagttgtg tgctctcaca caggcttcct 2100

 tctcgaccgg caggggctgg ctggcttgca ggccacgagg tgggctctac 2150

 cccacactgc tttgctgtgt atacgcttgt tgccctgaaa taaatatgca 2200

 cattttatcc atg 2213

<210> 2683
<211> 627
<212> PRT
<213> Homo sapien

<400> 2683
 Met Asp Trp Thr Trp Arg Phe Leu Phe Val Val Ala Ala Ala Thr
   1               5                  10                  15

 Gly Val Gln Ser Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val
                  20                  25                  30

 Lys Lys Pro Gly Ser Ser Val Lys Val Ser Cys Lys Ala Ser Gly
                  35                  40                  45

 Gly Thr Phe Ser Ser Tyr Ala Ile Ser Trp Val Arg Gln Ala Pro
                  50                  55                  60

 Gly Gln Gly Leu Glu Trp Met Gly Gly Ile Ile Pro Ile Phe Gly
                  65                  70                  75

 Thr Ala Asn Tyr Ala Gln Lys Phe Gln Gly Arg Val Thr Ile Thr
                  80                  85                  90

 Ala Asp Glu Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu
                  95                 100                 105

 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Gly Ile
                 110                 115                 120

 Leu Gly Pro Tyr Ser Ser Gly Trp Tyr Pro Asn Ser Asp Tyr Tyr
                 125                 130                 135

 Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val
                 140                 145                 150

 Ser Ser Gly Ser Ala Ser Ala Pro Thr Leu Phe Pro Leu Val Ser
                 155                 160                 165

 Cys Glu Asn Ser Pro Ser Asp Thr Ser Ser Val Ala Val Gly Cys
                 170                 175                 180

 Leu Ala Gln Asp Phe Leu Pro Asp Ser Ile Thr Phe Ser Trp Lys
                 185                 190                 195

 Tyr Lys Asn Asn Ser Asp Ile Ser Ser Thr Arg Gly Phe Pro Ser
                 200                 205                 210

 Val Leu Arg Gly Gly Lys Tyr Ala Ala Thr Ser Gln Val Leu Leu
                 215                 220                 225

 Pro Ser Lys Asp Val Met Gln Gly Thr Asp Glu His Val Val Cys
                 230                 235                 240

 Lys Val Gln His Pro Asn Gly Asn Lys Glu Lys Asn Val Pro Leu
                 245                 250                 255

 Pro Val Ile Ala Glu Leu Pro Pro Lys Val Ser Val Phe Val Pro
                 260                 265                 270

 Pro Arg Asp Gly Phe Phe Gly Asn Pro Arg Ser Lys Ser Lys Leu
                 275                 280                 285

 Ile Cys Gln Ala Thr Gly Phe Ser Pro Arg Gln Ile Gln Val Ser
                 290                 295                 300

 Trp Leu Arg Glu Gly Lys Gln Val Gly Ser Gly Val Thr Thr Asp
                 305                 310                 315

 Gln Val Gln Ala Glu Ala Lys Glu Ser Gly Pro Thr Thr Tyr Lys
                 320                 325                 330

 Val Thr Ser Thr Leu Thr Ile Lys Glu Ser Asp Trp Leu Ser Gln
                 335                 340                 345

 Ser Met Phe Thr Cys Arg Val Asp His Arg Gly Leu Thr Phe Gln
                 350                 355                 360

 Gln Asn Ala Ser Ser Met Cys Val Pro Asp Gln Asp Thr Ala Ile
                 365                 370                 375

 Arg Val Phe Ala Ile Pro Pro Ser Phe Ala Ser Ile Phe Leu Thr
                 380                 385                 390

 Lys Ser Thr Lys Leu Thr Cys Leu Val Thr Asp Leu Thr Thr Tyr
                 395                 400                 405

 Asp Ser Val Thr Ile Ser Trp Thr Arg Gln Asn Gly Glu Ala Val
                 410                 415                 420

 Lys Thr His Thr Asn Ile Ser Glu Ser His Pro Asn Ala Thr Phe
                 425                 430                 435

 Ser Ala Val Gly Glu Ala Ser Ile Cys Glu Asp Asp Trp Asn Ser
                 440                 445                 450

 Gly Glu Arg Phe Thr Cys Thr Val Thr His Thr Asp Leu Pro Ser
                 455                 460                 465

 Pro Leu Lys Gln Thr Ile Ser Arg Pro Lys Gly Val Ala Leu His
                 470                 475                 480

 Arg Pro Asp Val Tyr Leu Leu Pro Pro Ala Arg Glu Gln Leu Asn
                 485                 490                 495

 Leu Arg Glu Ser Ala Thr Ile Thr Cys Leu Val Thr Gly Phe Ser
                 500                 505                 510

 Pro Ala Asp Val Phe Val Gln Trp Met Gln Arg Gly Gln Pro Leu
                 515                 520                 525

 Ser Pro Glu Lys Tyr Val Thr Ser Ala Pro Met Pro Glu Pro Gln
                 530                 535                 540

 Ala Pro Gly Arg Tyr Phe Ala His Ser Ile Leu Thr Val Ser Glu
                 545                 550                 555

 Glu Glu Trp Asn Thr Gly Glu Thr Tyr Thr Cys Val Val Ala His
                 560                 565                 570

 Glu Ala Leu Pro Asn Arg Val Thr Glu Arg Thr Val Asp Lys Ser
                 575                 580                 585

 Thr Glu Gly Glu Val Ser Ala Asp Glu Glu Gly Phe Glu Asn Leu
                 590                 595                 600

 Trp Ala Thr Ala Ser Thr Phe Ile Val Leu Phe Leu Leu Ser Leu
                 605                 610                 615

 Phe Tyr Ser Thr Thr Val Thr Leu Phe Lys Val Lys
                 620                 625

<210> 2684
<211> 1869
<212> DNA
<213> Homo sapien

<400> 2684
 agatgacctt ttaggaaagt ggtgcattta ttaattgaac tgaagaagta 50

 gttcagttga attcagtatc ataattcaca aattggaggc tgttgatttt 100

 gattcattta aggtttaaaa tctttattaa ttgcaaacag tgcaattatt 150

 tatacttcac agtgccttcc cagaccttcc accttaggtt ctgctgcaaa 200

 aagcaccagt gctgaagatg ctgcaagcac caaatcatag ctcataaaat 250

 caggtcctga gatagttacc cataaagagg aatcctttga gtgtatgcca 300

 ttggtgagcc gatgagcatg gaccatagaa gggctcaatg tagaaggtaa 350

 aattggcaaa tcataattga gaaatatgaa atgtattccc atacataata 400

 tggtataggg tgtaatgtac ctgcttttga tcacttttca ttttaaagtg 450

 ctattcactt gatcttaaat gttccatgaa ctgttaaatt tcttaagtta 500

 catagttact acaccacatt tatgtgtatg ttatgtttta atagtcaatg 550

 ataggtatgt acaattgata atataaaggg gctcattgaa acttgagagc 600

 ctgttgagtt ttggttagtt gtagattgca tttttataaa aaaaaataca 650

 gatagattga tgataataga tattggggca ttgtttctgt ctcatgagaa 700

 ttcttttatt cattaccata agccttcact gatactataa gcattatttt 750

 aaatgacgct gatcttaagt ctgaaataaa tggaaagcag aaaaggtgag 800

 ccagttgatt tgaatgcatt ggatattagt gttagaaaca atgtatagtt 850

 tagattgaaa ctgaactgac ttatttagca cttaaacaaa aatttgacaa 900

 tgtttttagt tttttttaag acagcttagt gtggtgatac ttagaattct 950

 atggtttgat gtttctttta gaaatgagaa gtatagtttt attttttaat 1000

 ataaaaaatg gttttaatac taaaactagt aatttgatac tagttgttta 1050

 taaacattgt aaaatatatc ttttaaacaa attatcttgg tagttaattc 1100

 ataagggtgg gtttgggtag gaatagcaga gtactttcag agggaaaggg 1150

 gagtcattca gaagtgatag cattttattt gtttgaatac tctgccagta 1200

 aaatcagctg tacttagaaa gttatctgtt gtgtagaata atgatgtaga 1250

 gtttactaat cagtgaggat gtcttgtttt tattttctgc aaactctgcc 1300

 tcactttaaa atgcattata acaataccta attaaagata attttggctc 1350

 tgaaagttac cttatttttt gttgagttag tgacttcatt tttcttgcca 1400

 caatataagc ttttgaggga tttttttaaa ttggtgcttt taataagcaa 1450

 ataaatccca gggttttatt ttcttcagtg atacccctat agaaactctt 1500

 aaatgtattt gcgcatatat atatatatat tttcttatgc atgctcgatg 1550

 cattttcgtc ctgagaaaaa tgttctctac agaaactacc cgtgtgtaaa 1600

 aagaagattg gcttaaaatg gctactgtga tgggaacagt gtcttaggga 1650

 gatgcagctt ggacttgagg taaattgaat actttacaac tgtggtttag 1700

 agtttgcttt aatgacattg tatgtaaaag gtcacatgat tgctgtaatt 1750

 ttgtattcat tatggtttcc tcaataaatg tacattgatg acttattaaa 1800

 aaaaatctat gtcgggtgcg gagaaagagg taatgaaatg gcaggaattc 1850

 gatatcagct tatcatacc 1869

<210> 2685
<211> 12
<212> PRT
<213> Homo sapien

<400> 2685
 Met Lys Trp Gln Glu Phe Asp Ile Ser Leu Ser Tyr
   1               5                  10

<210> 2686
<211> 3446
<212> DNA
<213> Homo sapien

<400> 2686
 cagtttcagg gtctcgccgg cagccccagc cggcgggcgc ggagcgggca 50

 gcggggcccg gatcgcaggc tcctctgggg gccccggagt tgggaagcgg 100

 cgtccgggag cccccggagg aggatgggct gcagacacag caggctgagc 150

 agctgcaaac ccccgaaaaa gctataactg tccagctctg tgcatcagag 200

 gaggctgagc ggcaccagaa ggatataacc agaattctcc agcaacatga 250

 ggaggaaaag aagaaatggg cacaacaggt ggagaaggaa agggagctag 300

 agcttcgaga cagactggat gagcagcaaa gggtcctgga aggaaagaat 350

 gaagaggccc tgcaagtcct ccgggcctca tatgaacagg agaaagaagc 400

 gcttacccac tctttccggg aggccagttc tacccagcag gagaccatag 450

 acagactgac ctcacagctg gaggctttcc aggccaaaat gaagagggtg 500

 gaggagtcca ttctgagccg aaactataag aaacatatcc aggattatgg 550

 gagccccagc cagttctggg agcaggagct ggagagctta cactttgtca 600

 tcgagatgaa gaatgagcgt attcatgagc tggacaagcg gctgatcctc 650

 atggaaacag tgaaagagaa aaatctgata ttggaggaaa aaattacgac 700

 cctgcaacag gaaaatgagg acctccatgt ccgaagccgc aaccaggtgg 750

 tcctgtcaag gcagctgtca gaagacctgc ttctcacgcg tgaggccctg 800

 gagaaggagg tgcagctgcg gcgacagctc cagcaggaga aggaggagct 850

 gttgtaccgg gtccttgggg ccaatgcctc gcctgccttc cctctggccc 900

 ctgtcactcc cactgaggtc tctttcctcg ccacataggg tgcagggcct 950

 gggcccacca cgacgcctga agtcacagct ccttccaagg tttttctgga 1000

 gaagacagca ggagcctctc agttcttttc caggaaggaa cgagggtggg 1050

 agcgagatgg agatcctggg tgtgtgccca gtgagccctg gggccttgag 1100

 ttacatggaa tcacccacag ggttttggag gccccgagaa gcgtcttccc 1150

 ttgagttggc caagggaata agcaagagga gacatttcct ccctgcccca 1200

 gcactctgtc ccaatccgag aagttccgag gctttcccag gggcagtctg 1250

 tgtcacgctg gccatttgac ataaaggaga cagcccctgg tcccagcttg 1300

 tcagctctgc tgccgacttg ctgacttatc aacttcctct aggtgtttcc 1350

 actccaccct ggcctgctca gagcctcagt ttacccctgc attaaaatgg 1400

 tggggggact ggtcaaagga ctcttatgtc actgcagtgt cccattctag 1450

 gattgtctga aggccagagt aggggttggg gggagtgtgg acaaaccccg 1500

 caaatcagag tggggaaggt gagtggtaga gagggggtct ctgaaggccc 1550

 ttggggctga cagggccagg cagcctcccc agctgaggca tcattcctgg 1600

 gccagagtcg tgtccaccaa gggacagtag ccagagctcc tcttccttta 1650

 ccaggcaagg tgcatcccct cagccctcct ggcccttcag tcttggtgcc 1700

 acctgggcac aggggcaagc ttggtggttg tgagtccatt catctatcag 1750

 agctggaacc tcatccctgc acagatgagg aaaccaaggc atggagcagt 1800

 tcccagagtc gaatctagat ctcatctgtc atccgggtct tatcctttgc 1850

 tctgtttttc tcttcaggct ctggaaaatc agatctgtga cttaatcctc 1900

 tccctggccc tcacccactt agtttctttt tcattcctgc tccctgcctt 1950

 aactcctcct cccactgccc ctgatcccag gcccaggctt ttacaacctg 2000

 gtgctcagct tccccatcag tgaaaagggg tggctagagt aactaacctc 2050

 agcaggccct ccagtcctga tagtctgtgg atttcggatc cttctcagga 2100

 agcttcatgt ctaatggaga ctataattat aactcctgtt ctgcatagag 2150

 catttgcatc aaaggctttc catacccctc cctcccctgg tcctcataag 2200

 atccttgaag caggttccta ttcctcattg gcaacatggc aaacagatca 2250

 caggagtcaa agggccttgc tcaaggtccc cagcttcagc cccaggccct 2300

 aagccagcgt cagaacagtc aatctgcatt tttcatcagt cattctatag 2350

 tgacatcatc ccagactgcc ttctgtattc ccctgtgtac agtctccttc 2400

 tgtttctagg tttagaagtt cagaggtgac tgtgtttctc catttccaca 2450

 gccaaatggg ggaagaggtg aggctagggg agtgctgtgc tgattctcca 2500

 gccatggtca gacaggtcac ccaggagcct cgaggaaagc cctggaggga 2550

 atcacatgtg tactttttca tgaagctttt tgcaaagcac atctgtgata 2600

 cactagttta ttgaactaat gtccaggagt agacatgatt ggtggccaag 2650

 ttatttgggg acacctaaac agatcagtga cctgaatgac ttctcagaac 2700

 ctttaatatg ccaatgtgtg tggcaaactt acaagaaggg agctaagtat 2750

 ccagcctctc ccaaacctct ttgaacaaag cttctgtccc tcccacacct 2800

 ctcacctcac aggcacatca ggctgcagaa tgcgctttag aaagcattgt 2850

 tttagtccag gcacagtggc tcacgcctgt aatcccagca ctttgggagg 2900

 ccgaggtggg tggatcacaa ggttgggaga ttgagaccat cctggctaac 2950

 acagtgaaac cctgtctcta ctaaaaaaat acaaaaaatt agcttggcgt 3000

 ggtggtgggc gcctgtagtc ccagcagctt gggaggctga ggctggagaa 3050

 tggtgtgaac ccaggaggcg gagcttgcag tgagccaaga tcgcgccact 3100

 gcactccagc ccgggtgaca gagcaagact ccgtctcaaa aaaaagaaaa 3150

 gaaaaaagaa agcattgttt taattgagag gggcagggct ggagaaggag 3200

 caagttgtgg ggagccaggc ttccctcacg cagcctgtgg tggatgtggg 3250

 aaggagatca acttctcctc actctgggac agacgatgta tggaaactaa 3300

 aaagaacatg cggcacctta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3350

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3400

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 3446

<210> 2687
<211> 311
<212> PRT
<213> Homo sapien

<400> 2687
 Val Ser Gly Ser Arg Arg Gln Pro Gln Pro Ala Gly Ala Glu Arg
   1               5                  10                  15

 Ala Ala Gly Pro Gly Ser Gln Ala Pro Leu Gly Ala Pro Glu Leu
                  20                  25                  30

 Gly Ser Gly Val Arg Glu Pro Pro Glu Glu Asp Gly Leu Gln Thr
                  35                  40                  45

 Gln Gln Ala Glu Gln Leu Gln Thr Pro Glu Lys Ala Ile Thr Val
                  50                  55                  60

 Gln Leu Cys Ala Ser Glu Glu Ala Glu Arg His Gln Lys Asp Ile
                  65                  70                  75

 Thr Arg Ile Leu Gln Gln His Glu Glu Glu Lys Lys Lys Trp Ala
                  80                  85                  90

 Gln Gln Val Glu Lys Glu Arg Glu Leu Glu Leu Arg Asp Arg Leu
                  95                 100                 105

 Asp Glu Gln Gln Arg Val Leu Glu Gly Lys Asn Glu Glu Ala Leu
                 110                 115                 120

 Gln Val Leu Arg Ala Ser Tyr Glu Gln Glu Lys Glu Ala Leu Thr
                 125                 130                 135

 His Ser Phe Arg Glu Ala Ser Ser Thr Gln Gln Glu Thr Ile Asp
                 140                 145                 150

 Arg Leu Thr Ser Gln Leu Glu Ala Phe Gln Ala Lys Met Lys Arg
                 155                 160                 165

 Val Glu Glu Ser Ile Leu Ser Arg Asn Tyr Lys Lys His Ile Gln
                 170                 175                 180

 Asp Tyr Gly Ser Pro Ser Gln Phe Trp Glu Gln Glu Leu Glu Ser
                 185                 190                 195

 Leu His Phe Val Ile Glu Met Lys Asn Glu Arg Ile His Glu Leu
                 200                 205                 210

 Asp Lys Arg Leu Ile Leu Met Glu Thr Val Lys Glu Lys Asn Leu
                 215                 220                 225

 Ile Leu Glu Glu Lys Ile Thr Thr Leu Gln Gln Glu Asn Glu Asp
                 230                 235                 240

 Leu His Val Arg Ser Arg Asn Gln Val Val Leu Ser Arg Gln Leu
                 245                 250                 255

 Ser Glu Asp Leu Leu Leu Thr Arg Glu Ala Leu Glu Lys Glu Val
                 260                 265                 270

 Gln Leu Arg Arg Gln Leu Gln Gln Glu Lys Glu Glu Leu Leu Tyr
                 275                 280                 285

 Arg Val Leu Gly Ala Asn Ala Ser Pro Ala Phe Pro Leu Ala Pro
                 290                 295                 300

 Val Thr Pro Thr Glu Val Ser Phe Leu Ala Thr
                 305                 310

<210> 2688
<211> 1856
<212> DNA
<213> Homo sapien

<400> 2688
 cgagcttgat gtattgctca gtattcactt agaagggttt ctttctcttt 50

 ggcctagttt gtgaagggat cttcctttgg actttctcta agttgggaga 100

 agaacattct tttcaatgga gctcatcttc tatctctagg gtctgttcag 150

 cctttcatct atccatcctt cctctttatt ggtagaagaa acagtggaga 200

 gtagccactt ctggttctag cacttctctt ttgttaagat agggtttgga 250

 tttagtatga agctttggct aaaacccttg ggtttgcctt agaacactga 300

 cactaagaac ctggaatgac atggggagga caaagagagc tcaagaggaa 350

 tgctttgtga gaagtggatt ctctccgtgt ccctgccccc cacccaaact 400

 tgaactatac ctattacatt tccaggcagt atccctaaga tgagatcctg 450

 gagaaaggac taggggaagt atctttctgg atgcttgtgg tcccagaagg 500

 gtactttctg tgtcatacca tgccacttct ttaagctctt cagggcagcc 550

 aaagccagcc cttttctcct actgccccca ggagaaatag cactcttctc 600

 ccttccccca gatggcaggg ctctggcctc cctacacctc ataccctgcc 650

 tgcctcctcc aggaggaatc tccggggccc cttcctgact ctccccacct 700

 tcgccacttg tctctaggct atgggacaat catcccattc accacttgac 750

 atccttgaca tccttgactt tcattccccc aacctccagc aggttggccc 800

 caatcctctt cacctctgtg ttttcttcta gaagatgcat tttgggtctg 850

 agaggagcat tttcctggaa ggccatcttt taaggcccct gcttgctgtc 900

 atagtgcaga gcagaaactt gcacactatt tagagagctc ccttcccacc 950

 tctctgccca gccttgttac ctcacttctg ctctggccat ggctgtgaag 1000

 ggcccagcca gctccctgtt ttgatgttct gtgcaacagc tccggggtct 1050

 tgtgactgga gatcctcaac aggccctgga gccaggactg gagtcttggc 1100

 agctgatgag cagcaccttg ccggccagga ggagctgatg ctgacgatct 1150

 ccccaacatc tgaaggctta aagaacattg tcgttcttca gccctccttg 1200

 cttctctcaa tacaataaga cattgcagaa gcaaaagggt ggcctctgct 1250

 ccaggcaagg cagctggctc tgtctggggc gtcggcctgg ggcttgggtg 1300

 ccacgtgctg agattgcata gtcaaaacag ccatttttgc caacaatagc 1350

 ttgtggctcc ccacattttc ctaccctgca ctcaagggcc agaccactct 1400

 ctgcatggac cagaccatct tcccaaaccc atggtgcttt ttccccaact 1450

 caacctagac tccaaggtgg ggagggatgg gtcagaggcc atagtggccc 1500

 ctggataatc ctgacgtggg gtggagtggg gtgaggcaga gggagcagcc 1550

 ccaacacctg cactgggcca tctatgggaa agaacacggg tcgagtgcag 1600

 tcgagttgtc tggccatctg tatttggatc tataactgta ctttgcctgg 1650

 cgctgtgcgc aaggtcagaa aacttactgc tagtacctag aaacacacaa 1700

 ggctgcccag ccaaatctta atgtaaagta gctagagcca tggaagtaca 1750

 gtatgaatta aaaagaaaaa agtattgaac tcctaaaaaa aatctatgtc 1800

 gggtgcggag aaagaggtaa tgaaatggca ggaattcgat atcagctatc 1850

 atacct 1856

<210> 2689
<211> 11
<212> PRT
<213> Homo sapien

<400> 2689
 Met Lys Trp Gln Glu Phe Asp Ile Ser Tyr His
   1               5                  10

<210> 2690
<211> 1843
<212> DNA
<213> Homo sapien

<400> 2690
 ggcacgagca agacatcaac tgaatgagga ttttaaaaaa tggtatataa 50

 gcataggaca agggctatgt ttgtttgttt ttcaaaagtg ctttgaagat 100

 aacagccttt aggtttgagt tatttcactt ttcataattt ttaagtagct 150

 tatatataat ggtggtacca taggattttc ttttttcaaa tgactgtcgg 200

 cagaaacagt gggcactgac tcaccttttg agttttagca gagaattatt 250

 tatttcttta caatgcactt tctaacccat tgtagctata ttagcattat 300

 cttttaaaaa agacatgctt ttgtatttaa atattgtagg atttaagtgt 350

 ctttctcaaa atagcttatt cctttctgaa agaaaatgag ggaaatactc 400

 tgaattatta ggagacttaa acccaatatt taaatatgct attttataac 450

 actgcatcag ttttaggagt tgcatctctc ctgctggctc ttttatattt 500

 gagcaagatc agtgtagaat atgtgtttag aaacttgtct gttgtctcag 550

 tttagtgaaa aggaggtgct gcatgtgcct gaattaaaac caagaaattt 600

 ttccaagcca aatgcagcct tagtgatgag agatttaatt ctccattgtc 650

 accttttagc ttttatgatt gcttagtttt ttctgaagga tgtctgcatt 700

 gtaaaactat ggactaaaac ctaaaaaaca gaatcctcaa aaactttgct 750

 gtatgtgttt taacatttta gagaacagta tgttgaataa ctaaggtatg 800

 taacttgaat aggaaaaatg tccatcaaat gcaccttgga aaatcacagt 850

 aggtagaagg ctgtgttaac cgtttgtgtc ttattaacat ccttaagtta 900

 attttgaatt tttgacagtt ttgagggaaa agacctatgg aacctaatgt 950

 gaagtatttc gtatgttaac tggtgttgag ttgaagattt ttactgtgta 1000

 taagcagata tcatttgaat gataaaaatg tcattaacct gctgtcttaa 1050

 gatgttcaca caaatatgga gagtaattct acaatataaa aatatttatt 1100

 ttaatactga gtttcagtta agtcataaac agtgttaaaa ctcttgggaa 1150

 ggtgtagggg ttttttgttt gtcattttta aaattgaaac tgtgtcatac 1200

 agtgtttcac gtctctgaaa ttgggattat aatagcacta ttttgatgta 1250

 gctctaccga tactatgtgg taatgctatt ttgttttact aacaagctct 1300

 ggaatattta gcagtcattt tcactggcac aagagccttt tgtatgttat 1350

 tcaatttaaa cttttaaacc aaaaatttta tggtccagtg tctttggcaa 1400

 aaagatgctg gagggaatgt aacatacaat taatatgtgg ttatatatat 1450

 atataaaaag acacaaattg ccatgttatg gttctgcctt gaaacagcac 1500

 aatgaagtgt atcagtatat tctgtgatta tgaaacttat atgttgtgtt 1550

 gttttgtgtc ttctgttgcc tgtcctttgg gccagatgtg ggccagttaa 1600

 atgcagttat catctcatta aatacagatg cagataaaat atctttagtg 1650

 ctgcaacatt ttacctaact ttttgtatgt tttcatgact gtgtgttatt 1700

 ttccaaagct gttcctacct caccatgagg ctttatggat tgttatgtat 1750

 tataaatgtt ctatatgaga cagactactg tgtttcttct catttattaa 1800

 aagttaagta gaaaaataaa ctaattttaa tatctaaaaa aaa 1843

<210> 2691
<211> 1694
<212> DNA
<213> Homo sapien

<400> 2691
 gcggccgcgc cccgccgcca ccatgagggc cgagggcctc ggcggcctgg 50

 agcgcttctg cagcccgggc aaaggccggg ggctgcgggc tctgcagccc 100

 ttccaggtgg gggacttgct gttctcctgc ccggcctatg cctacgtgct 150

 cacggtcaac gagcggggca accactgcga gtactgcttc accaggaaag 200

 aaggattgtc caaatgtgga agatgcaagc aggcatttta ctgcaatgtg 250

 gagtgtcaga aagaagattg gcccatgcac aagctggaat gttctcccat 300

 ggttgttttt ggggaaaact ggaatccctc ggagactgta agactaacag 350

 caaggattct ggccaaacag aaaatccacc cagagagaac accttcggaa 400

 aaattgttag ctgtgaagga gtttgaatca catctggata agttagacaa 450

 tgagaagaag gatttgattc agagtgacat agctgctctc catcactttt 500

 actccaagca tctcgaattc cctgacaatg atagcctcgt agtactcttt 550

 gcacaggtta actgtaatgg cttcacaatt gaagatgaag aactttctca 600

 tttgggatca gcgatatttc ctgatgttgc attgatgaat catagctgtt 650

 gccccaatgt cattgtgacc tacaaaggga ccctggcaga agtcagagct 700

 gtacaggaaa tcaagccggg agaggaggtt tttaccagct atattgatct 750

 cctgtaccca acggaagata gaaatgaccg gttaagagat tcttatttct 800

 ttacctgtga gtgccaggag tgtaccacca aggacaagga taaggccaag 850

 gtggaaatcc ggaagctcag cgatccccca aaggcagaag ccatccgaga 900

 catggtcaga tatgcacgca acgtcattga agagttccgg agggccaagc 950

 actataaatc ccctagtgag ctgctggaga tctgcgagct cagccaggag 1000

 aagatgagct ctgtgtttga ggacagtaac gtgtacatgt tgcacatgat 1050

 gtaccaggcc atgggtgtct gcttgtacat gcaggactgg gaaggagccc 1100

 tgcaatatgg acagaaaatc attaagccct acagtaagca ctatcctttg 1150

 tactccctca acgtggcctc catgtggttg aagctaggga gactctacat 1200

 gggcctggaa cacaaagccg caggggagaa agccctgaag aaggccattg 1250

 caatcatgga agtagctcac ggcaaagatc atccatatat ttctgagatc 1300

 aaacaggaaa ttgaaagcca ctgaaactat gcagcatttc agttttcatt 1350

 taaacactta gttcagaaac cttaaaggat ttgaatattt caaattgcac 1400

 acgtcactcc agcatctctg taaaataatt ggaatgaaaa tacttcttgc 1450

 acttaaacac tgcacatgcc gtactttgag gttagtctga atcttgaact 1500

 ttaataccaa attaattttg aatgcttttg tttcctaaga gataatggca 1550

 tggtttcata tgttatactt tggacagagt tttaaaaatg gaattatttt 1600

 ttctttcatg cctcttgtaa tgttctgaac aaacttgaat gatgaaagta 1650

 ttaaagagat atcagtaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1694

<210> 2692
<211> 433
<212> PRT
<213> Homo sapien

<400> 2692
 Met Arg Ala Glu Gly Leu Gly Gly Leu Glu Arg Phe Cys Ser Pro
   1               5                  10                  15

 Gly Lys Gly Arg Gly Leu Arg Ala Leu Gln Pro Phe Gln Val Gly
                  20                  25                  30

 Asp Leu Leu Phe Ser Cys Pro Ala Tyr Ala Tyr Val Leu Thr Val
                  35                  40                  45

 Asn Glu Arg Gly Asn His Cys Glu Tyr Cys Phe Thr Arg Lys Glu
                  50                  55                  60

 Gly Leu Ser Lys Cys Gly Arg Cys Lys Gln Ala Phe Tyr Cys Asn
                  65                  70                  75

 Val Glu Cys Gln Lys Glu Asp Trp Pro Met His Lys Leu Glu Cys
                  80                  85                  90

 Ser Pro Met Val Val Phe Gly Glu Asn Trp Asn Pro Ser Glu Thr
                  95                 100                 105

 Val Arg Leu Thr Ala Arg Ile Leu Ala Lys Gln Lys Ile His Pro
                 110                 115                 120

 Glu Arg Thr Pro Ser Glu Lys Leu Leu Ala Val Lys Glu Phe Glu
                 125                 130                 135

 Ser His Leu Asp Lys Leu Asp Asn Glu Lys Lys Asp Leu Ile Gln
                 140                 145                 150

 Ser Asp Ile Ala Ala Leu His His Phe Tyr Ser Lys His Leu Glu
                 155                 160                 165

 Phe Pro Asp Asn Asp Ser Leu Val Val Leu Phe Ala Gln Val Asn
                 170                 175                 180

 Cys Asn Gly Phe Thr Ile Glu Asp Glu Glu Leu Ser His Leu Gly
                 185                 190                 195

 Ser Ala Ile Phe Pro Asp Val Ala Leu Met Asn His Ser Cys Cys
                 200                 205                 210

 Pro Asn Val Ile Val Thr Tyr Lys Gly Thr Leu Ala Glu Val Arg
                 215                 220                 225

 Ala Val Gln Glu Ile Lys Pro Gly Glu Glu Val Phe Thr Ser Tyr
                 230                 235                 240

 Ile Asp Leu Leu Tyr Pro Thr Glu Asp Arg Asn Asp Arg Leu Arg
                 245                 250                 255

 Asp Ser Tyr Phe Phe Thr Cys Glu Cys Gln Glu Cys Thr Thr Lys
                 260                 265                 270

 Asp Lys Asp Lys Ala Lys Val Glu Ile Arg Lys Leu Ser Asp Pro
                 275                 280                 285

 Pro Lys Ala Glu Ala Ile Arg Asp Met Val Arg Tyr Ala Arg Asn
                 290                 295                 300

 Val Ile Glu Glu Phe Arg Arg Ala Lys His Tyr Lys Ser Pro Ser
                 305                 310                 315

 Glu Leu Leu Glu Ile Cys Glu Leu Ser Gln Glu Lys Met Ser Ser
                 320                 325                 330

 Val Phe Glu Asp Ser Asn Val Tyr Met Leu His Met Met Tyr Gln
                 335                 340                 345

 Ala Met Gly Val Cys Leu Tyr Met Gln Asp Trp Glu Gly Ala Leu
                 350                 355                 360

 Gln Tyr Gly Gln Lys Ile Ile Lys Pro Tyr Ser Lys His Tyr Pro
                 365                 370                 375

 Leu Tyr Ser Leu Asn Val Ala Ser Met Trp Leu Lys Leu Gly Arg
                 380                 385                 390

 Leu Tyr Met Gly Leu Glu His Lys Ala Ala Gly Glu Lys Ala Leu
                 395                 400                 405

 Lys Lys Ala Ile Ala Ile Met Glu Val Ala His Gly Lys Asp His
                 410                 415                 420

 Pro Tyr Ile Ser Glu Ile Lys Gln Glu Ile Glu Ser His
                 425                 430

<210> 2693
<211> 1482
<212> DNA
<213> Homo sapien

<400> 2693
 aactggcgca ggggccgctg cggcaaggac tggttgccat aaaggaagcc 50

 cacgacatag agaccaggct taatgaggtg gagaagctgc tgaagacgat 100

 cataagcatg ccctgtaaat attctagatc ggaagttgtg ctcaccttct 150

 tcgaaagatc tcctctggat caggtgttaa aaaatgataa tgtgcataaa 200

 attcaaccca gctttcaaag tccagtcaaa atatcagaaa tcatgaggtc 250

 caatggattt tgtttagcaa ataccgaaac aatagttatt gaccacagta 300

 taccaaatgg aagagaccag cagctgggcg tggaccaaac agagcattta 350

 tttgagaatg gcagtgagtt tccctcagag ctggaggacg gggacgaccc 400

 agcagcctac gtcaccaacc tgtcatatta ccacctggtc cccttcgaga 450

 cagacatttg ggactgaacc tctctatcag gcctcccccg cctcagctgt 500

 tcactgccag ctctgatgct gtccactgtg ctggccccca tggtcacagc 550

 tgctgcccca gctctggaac tcccagacgt cccaggcccc actgacgcca 600

 ggaggcctgg gtgtcctgca agtggagcag caggggctcc tagtgggcca 650

 ggctgaccgc agagtctcca gcaagctgag gtcacagccg gaggccacag 700

 ggcctgtgtt ctgagggtct tcactccctg cttggtgccc acagggctgc 750

 gcactgccag ggcagggaca gttcctgtgg ggctcgctct cactgctact 800

 gcttcctggg aggtgcatcc ctcttggtga agtggcctag tgccccccag 850

 ccaccctgac tccccaccat tccctcccac ggcaaacgca caaaacgtct 900

 tgagggagat tttgacaagt cacccattcc aggtgccaca ggcaggggat 950

 gtttagtaat ccaggatttc tctgagaact gggatatgtg gccttttttt 1000

 ttttcttttt atcttttatc tggaaactgg gtttgggtca accccaggag 1050

 tatttgcaga aggcccagca cagtgggggg tattggctgc agggcaggga 1100

 aggcattgcc gactagataa ccgtgtgagc ttggactgag cgttggtggt 1150

 tcttcccaaa ggaaaggaat ttcttcccgg cctgccaggt ctctgggcct 1200

 tcagcgcggg tcctggtgct gcggccacac caccctgggg tgctcattga 1250

 cagagctgcc ataatgaact tgaaaggacg ggaatcacga gggaagctgg 1300

 ggctcccctg cccacaggag aggatccccg ttcttcaagc ttctctgctc 1350

 agtgtctact aacgaccgac atttgctaat gtaaataata gtaaattatt 1400

 gagaattcta attcttttac acagtctgtt tttaatctat tttaattaaa 1450

 taaaatctat gactccaaaa aaaaaaaaaa aa 1482

<210> 2694
<211> 4623
<212> DNA
<213> Homo sapien

<400> 2694
 gtcacgcccc gggcagcttg gctggggcta ggcttccggg gctctgcggt 50

 cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga 100

 tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc 150

 gtgtgggagc ggccgtggtc ggtggaggag atccgcagga gcagccagag 200

 ctggtcgctg gcggccgacg cgggcctact acagtttcta caggaattct 250

 cacagcaaac tatctctagg acccatgaaa tcaagaaaca agtggacgga 300

 ctaatccggg aaaccaaagc cacagattgt cgcctgcata atgtcttcaa 350

 tgacttcctt atgctctcta atacccagtt catagagaat cgtgtatatg 400

 atgaagaagt ggaggagcca gtactcaagg ctgaggcaga aaaaacagag 450

 caggagaaga cacgagagca gaaagaagta gatctcattc ctaaagtcca 500

 ggaggctgtg aactatggct tacaagtatt ggacagtgcc tttgagcaac 550

 ttgatatcaa agcaggaaac tcagactccg aggaagatga tgctaatggg 600

 cgggtggaac tgatccttga accaaaggat ctatacattg atcgtccttt 650

 accatatctc attgggtcaa agctgttcat ggaacaagaa gatgtaggtc 700

 ttggagagct gtccagtgaa gaaggctctg taggcagtga tcgtggcagt 750

 attgtggaca ctgaggaaga gaaagaagag gaggagtcag atgaagattt 800

 tgcccatcac agtgacaatg aacaaaacca gcacaccaca caaatgagtg 850

 atgaggaaga ggatgatgat ggctgtgacc tttttgctga ctctgagaag 900

 gaggaggaag atattgagga cattgaagaa aatactagac ctaaaagaag 950

 cagacctaca tcgtttgcag atgagctggc tgcccgcatc aagggggatg 1000

 ccatgggtcg agtggacgag gagccgacaa ccttaccctc aggagaagca 1050

 aaacctcgga agacactcaa agagaagaag gaaaggagaa ctccttcaga 1100

 cgatgaagag gataacttat tcgcaccccc caagctgacc gacgaggact 1150

 tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta 1200

 tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga 1250

 tcggcaagct ggagcctctg ttaaggagga gtcttcatca tccaaacctg 1300

 gaaagaaaat cccagcagga gctgtttctg tatttttagg agacacggat 1350

 gtgtttggtg ctgcctccgt tccatcactg aaggagccac agaagcctga 1400

 gcagcccact ccaaggaaaa gcccctatgg tccccctccc actggcctct 1450

 ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac 1500

 agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg 1550

 tgacgaagaa ggagatctgt tcaaagaaaa agccgtagca tcgccagaag 1600

 ccactgtgag tcagacagat gaaaataaag caagagcaga aaaaaaggtt 1650

 accttatctt ccagcaagaa tctcaagccc tcatcagaaa caaagactca 1700

 aaaaggctta ttttcagatg aggaggactc tgaggatttg ttttcttctc 1750

 aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc 1800

 acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg 1850

 gggtacagct gctaagaagc agacattgtc tctacaagct cagagagaag 1900

 agaaagcaaa agcctccgag ctctccaaaa agaaagcatc tgccctgttg 1950

 ttcagcagtg atgaggagga ccagtggaat attcctgctt cacagaccca 2000

 cttagcatct gacagcaggt ctaaaggaga acccagggat tctgggaccc 2050

 tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa 2100

 gacaaagaag atgatctttt tgccattgcc aaggacagcc aaaagaagac 2150

 ccagagagtg tcactcctct ttgaagacga tgttgatagc ggaggctctc 2200

 tgtttggctc tcctcccaca tctgttcctc ctgcaacaaa gaaaaaagag 2250

 actgtctctg aggcaccacc tttgctgttc agcgatgaag aagagaagga 2300

 ggcacaactt ggagtgaagt ctgtggataa gaaggttgag agtgccaagg 2350

 agtcattaaa atttgggaga actgatgtgg ctgagtcaga aaaggaagga 2400

 cttttgacta gatctgctca ggaaacagtc aagcattctg atttattttc 2450

 ttcatcatcc ccatgggaca aaggaaccaa gcctagaacc aaaactgttc 2500

 ttagcttgtt tgatgaggaa gaggataaaa tggaagatca aaacattatc 2550

 caggctccac agaaagaagt aggaaagggc tgcgatcctg atgcccaccc 2600

 caagagcaca ggtgtcttcc aggatgaaga gctgcttttc agccacaagc 2650

 tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa 2700

 accaagctgt tagagccaag tgttgggagc ctgtttgggg atgatgaaga 2750

 tgatgatctt ttcagctctg ccaagtccca gcctttggta caagagaaaa 2800

 agagagtagt gaaaaaagac cactctgtta actctttcaa aaaccagaaa 2850

 catcctgaat ccattcaagg tagtaaagaa aaaggcatat ggaagccgga 2900

 aacacctcag gcaaatttag cgatcaaccc agcggccttg ctgcccacag 2950

 cggcttccca gatctctgaa gtaaagcctg ttttgccaga attggctttt 3000

 ccttcatctg aacacagaag gagccacggt ctggaaagtg tgcctgtcct 3050

 tcccgggagt ggggaggccg gtgtgagttt tgatcttcca gctcaggcag 3100

 acaccttaca cagtgcaaac aagagccgtg tcaagatgag agggaagcgt 3150

 agaccgcaga cccgtgcagc taggcggctg gctgctcagg agtccagcga 3200

 ggctgaggac atgagcatcc ccagaggacc cattgcacag tgggctgatg 3250

 gcgccatttc cccaaatggc catcggccac agctcagagc agccagtgga 3300

 gaagacagca ctgaggaggc cctggcagct gccgctgcac cttgggaagg 3350

 tggtcctgtg cctggagtgg acacaagccc ctttgcaaag tctctgggtc 3400

 attccagagg ggaggctgac ctttttgatt ctggggacat tttttccacg 3450

 ggcactggat ctcagtccgt ggagagaaca aaacccaagg caaagatagc 3500

 agagaatcct gccaacccac cagtgggtgg taaagcaaag agccccatgt 3550

 ttcctgctct aggcgaggcc agcagtgatg atgatctctt tcagtctgct 3600

 aaaccaaaac cagcaaagaa aacaaatccc tttcctctcc tggaagatga 3650

 ggatgacctc tttacagatc agaaagtcaa gaagaatgag acaaaatcca 3700

 gtagtcagca ggatgtcata ttaacaacac aagatatttt tgaggatgat 3750

 atatttgcta cggaagcaat taaaccctct cagaaaacca gagagaagga 3800

 gaaaacattg gaatctaatt tatttgatga taacattgat atctttgctg 3850

 acttaactgt aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag 3900

 tctatatttg atgatgatat ggatgacatc ttctcctctg gtatccaggc 3950

 taagacaacc aaaccaaaaa gccgatctgc acaggccgca cctgaaccaa 4000

 gatttgaaca caaggtgtcc aacatctttg atgatcccct gaatgccttt 4050

 ggaggccagt agagcacaca gggtatccac atgttaccct gcagctacat 4100

 tgttgagtta gtgatgatgt tgtatatgct gatggtctta actggattac 4150

 aaaaagcaaa tactagaaca gctagctcat cgttcaccca atgtacttgg 4200

 tatttttctg cactggttta atcatgctta atactacaaa acaaaaataa 4250

 atatttcaca gtggttggtt tgttttgttt ttaaaccaca gtttgattta 4300

 gttagccttg ctggggccat aatatgcttc agggtgtgta aaagaagaaa 4350

 tctctttgtg gctttcatgg gcagggaatc tcagagatag caaatgccac 4400

 ctgaccagaa gtctttgtta tatggatggg aaccctaact tagggcttgg 4450

 gcaggggaaa gagaaagaag atgagagatt atacttcatg agtcttagca 4500

 atatgggagc aggttttcac tgaattctga gggtgcctct gcatgtcctc 4550

 caaggcaaag tttggcaaac tgtggccccc ccactgtcat attttgttaa 4600

 taaaatttta ttggaacaca atc 4623

<210> 2695
<211> 3635
<212> DNA
<213> Homo sapien

<400> 2695
 agatggctgc cgacagtgag cccgaatccg aggtatttga gatcacggac 50

 ttcaccactg cctcggaatg ggaaaggttt atttccaaag ttgaagaagt 100

 cttgaatgac tggaaactga ttggaaactc tttgggaaag ccactcgaaa 150

 agggtatatt tacttctggc acatgggaag agaaatcaga tgaaatttcc 200

 tttgctgact tcaagttctc agtcactcat cattatcttg tacaagagtc 250

 cactgataaa gaaggaaagg atgagttatt agaggatgtt gttccacaat 300

 ctatgcaaga tttgctgggt atgaataatg actttcctcc aagagcacat 350

 tgcctggtaa gatggtatgg gctacgtgag ttcgtggtga ttgcccctgc 400

 tgcacacagt gacgctgttc tcagcgaatc taagtgcaac cttcttctga 450

 gttctgtttc tattgccttg ggaaacactg gctgtcaggt gccactcttt 500

 gtgcaaattc accacaaatg gcgaagaatg tatgtaggag aatgtcaagg 550

 tcctggtgta cgaactgatt tcgaaatggt tcatcttaga aaagtgccaa 600

 atcagtacac tcacttatca ggtctgctgg atatcttcaa atcaaagatt 650

 ggatgtcctt taactccatt gcctccagtt agtattgcta ttcgatttac 700

 ctatgtactt caagattggc agcagtattt ttggcctcag caacctccag 750

 acatagatgc ccttgtagga ggagaagttg gaggcttgga gtttggcaag 800

 ttaccatttg gtgcctgcga agatcctatt agtgaactcc atttagctac 850

 tacatggcct catctgaccg aagggatcat tgtggataat gatgtttatt 900

 ctgatttgga tcctattcaa gctccacatt ggtctgttag agttcgaaaa 950

 gctgagaatc ctcagtgttt gctaggtgat tttgtcactg aattttttaa 1000

 aatttgccgt cgaaaggagt caactgatga gattcttgga cgatctgcat 1050

 ttgaggaaga aggcaaagaa actgctgata taactcatgc tttgtcaaaa 1100

 ttgacagagc cggcatcagt tccaattcat aaattatcag tttcaaatat 1150

 ggtacacact gcaaagaaga aaatccgaaa acacagaggt gtagaggagt 1200

 caccgctaaa taatgatgtt cttaatacta ttctcctgtt cttattccct 1250

 gatgctgttt ctgagaaacc attagatgga actacttcaa cagataataa 1300

 taatcctcca tcagagagtg aagactataa tctctacaat cagttcaagt 1350

 ctgcaccatc tgacagttta acatacaaac tggctttgtg tctctgtatg 1400

 atcaattttt accatggagg gttgaaagga gtggcacacc tctggcagga 1450

 atttgttctt gaaatgcgtt tccgatggga aaacaacttt ctgattccag 1500

 gattagcaag tggaccccca gatctgaggt gttgtttact gcatcagaaa 1550

 ctacagatgt taaattgttg tattgaaaga aagaaggcac gtgatgaggg 1600

 gaaaaagaca agtgcttcag atgtcactaa tatatatcca ggggatgctg 1650

 gaaaagcagg agaccagttg gtgccagata atctaaaaga aacagataag 1700

 gaaaagggag aggtaggaaa atcttgggat tcctggagtg acagcgaaga 1750

 agaatttttt gaatgcctaa gtgatactga agaacttaaa ggaaatggac 1800

 aagagagtgg caagaaagga ggacctaagg agatggcaaa tttaaggccg 1850

 gaaggacggc tctatcagca tgggaaactt acactgctgc ataatggaga 1900

 acctctctac attccagtaa cccaggaacc agcacctatg acagaagatc 1950

 tgctagaaga gcagtctgaa gttttagcta aattaggtac atcggcagag 2000

 ggggctcacc ttcgagcacg catgcagagt gcctgtctgc tctcagatat 2050

 ggagtctttt aaggcagcta atccaggttg ctccctggaa gattttgtga 2100

 ggtggtattc accccgggat tatattgaag aggaggtgat tgatgaaaag 2150

 ggcaatgtgg tgctgaaagg agaactgagt gcccggatga agattccaag 2200

 caatatgtgg gtagaagcct gggaaacagc taagccaatt cctgctagaa 2250

 ggcaaaggag actctttgat gatacacggg aagcagaaaa ggtgctgcac 2300

 tatctggcaa tccagaaacc tgcagacctt gctcggcacc tgttaccttg 2350

 tgtgattcat gcagctgtac tcaaggtaaa ggaagaagaa agtctcgaaa 2400

 acatttcttc agttaagaag atcataaagc agataatatc ccattccagt 2450

 aaagttttgc acttccccaa tccagaagac aagaaattgg aagaaatcat 2500

 tcaccagatt actaatgtgg aagctctcat tgccagagct cggtcactaa 2550

 aagccaagtt tggaactgag aaatgtgaac aggaggagga aaaggaagat 2600

 cttgaaaggt ttgtgagttg cctgctggag cagcctgaag tgttagtcac 2650

 cggtgcagga agaggacatg ctggcaggat cattcacaag ctgtttgtga 2700

 atgcccagag ggctgcagct atgactccac cagaggagga attgaagaga 2750

 atgggctccc cagaggaaag aaggcagaac tccgtgtcag acttcccacc 2800

 ccctgctggc cgggaattca ttttgcgcac cactgtgccg cgccctgctc 2850

 cctactccaa agctctgcct cagcggatgt acagtgttct caccaaagag 2900

 gactttagac ttgcaggtgc cttttcatca gatacttcct tcttctgatt 2950

 cttctagcat tactcgttgg tggcttcaga gacagtgctg cctcctcctg 3000

 agggagggaa ggtaccaggg agaacctggg aggtcctgga gagggccctg 3050

 tccagttggg tgatcaggaa tcaaaccagc atcggaaaga cttcccagca 3100

 ccaagcttga gctgtgtcgt ttcgtggagg gggcagcgag gatgggcttg 3150

 agctgttgag agatttctgc cctagagatg gcctttgtat atgggggggt 3200

 ggtgggggga cacaaacaca tcagacactc cgtcctcaca ctggcaggac 3250

 ggtgttcatc gcattctctt ctgtgaccag cctctaggct agcggctgca 3300

 ttcgtggtct gtgcaaacac ttcgtggttc tatatatcag cagcaagtgt 3350

 gcaaaataaa ggacctgtta actcagattt ctggatattt tggtggtagc 3400

 ttctagtccc agaatctgtg tttttaaaat actacatgac attctgtcta 3450

 ttcaatcacc tggtggtcat ctttcttgta ctaattaact gttgatgagc 3500

 attttggata ttctaggaga aagcctataa tttcacatag tttctctttt 3550

 tcatgtaact gtaacctaaa tgtattactt ctgataaaac tatatatcaa 3600

 atgtcactgc aaattagttt tatatctgtc atgtg 3635

<210> 2696
<211> 981
<212> PRT
<213> Homo sapien

<400> 2696
 Met Ala Ala Asp Ser Glu Pro Glu Ser Glu Val Phe Glu Ile Thr
   1               5                  10                  15

 Asp Phe Thr Thr Ala Ser Glu Trp Glu Arg Phe Ile Ser Lys Val
                  20                  25                  30

 Glu Glu Val Leu Asn Asp Trp Lys Leu Ile Gly Asn Ser Leu Gly
                  35                  40                  45

 Lys Pro Leu Glu Lys Gly Ile Phe Thr Ser Gly Thr Trp Glu Glu
                  50                  55                  60

 Lys Ser Asp Glu Ile Ser Phe Ala Asp Phe Lys Phe Ser Val Thr
                  65                  70                  75

 His His Tyr Leu Val Gln Glu Ser Thr Asp Lys Glu Gly Lys Asp
                  80                  85                  90

 Glu Leu Leu Glu Asp Val Val Pro Gln Ser Met Gln Asp Leu Leu
                  95                 100                 105

 Gly Met Asn Asn Asp Phe Pro Pro Arg Ala His Cys Leu Val Arg
                 110                 115                 120

 Trp Tyr Gly Leu Arg Glu Phe Val Val Ile Ala Pro Ala Ala His
                 125                 130                 135

 Ser Asp Ala Val Leu Ser Glu Ser Lys Cys Asn Leu Leu Leu Ser
                 140                 145                 150

 Ser Val Ser Ile Ala Leu Gly Asn Thr Gly Cys Gln Val Pro Leu
                 155                 160                 165

 Phe Val Gln Ile His His Lys Trp Arg Arg Met Tyr Val Gly Glu
                 170                 175                 180

 Cys Gln Gly Pro Gly Val Arg Thr Asp Phe Glu Met Val His Leu
                 185                 190                 195

 Arg Lys Val Pro Asn Gln Tyr Thr His Leu Ser Gly Leu Leu Asp
                 200                 205                 210

 Ile Phe Lys Ser Lys Ile Gly Cys Pro Leu Thr Pro Leu Pro Pro
                 215                 220                 225

 Val Ser Ile Ala Ile Arg Phe Thr Tyr Val Leu Gln Asp Trp Gln
                 230                 235                 240

 Gln Tyr Phe Trp Pro Gln Gln Pro Pro Asp Ile Asp Ala Leu Val
                 245                 250                 255

 Gly Gly Glu Val Gly Gly Leu Glu Phe Gly Lys Leu Pro Phe Gly
                 260                 265                 270

 Ala Cys Glu Asp Pro Ile Ser Glu Leu His Leu Ala Thr Thr Trp
                 275                 280                 285

 Pro His Leu Thr Glu Gly Ile Ile Val Asp Asn Asp Val Tyr Ser
                 290                 295                 300

 Asp Leu Asp Pro Ile Gln Ala Pro His Trp Ser Val Arg Val Arg
                 305                 310                 315

 Lys Ala Glu Asn Pro Gln Cys Leu Leu Gly Asp Phe Val Thr Glu
                 320                 325                 330

 Phe Phe Lys Ile Cys Arg Arg Lys Glu Ser Thr Asp Glu Ile Leu
                 335                 340                 345

 Gly Arg Ser Ala Phe Glu Glu Glu Gly Lys Glu Thr Ala Asp Ile
                 350                 355                 360

 Thr His Ala Leu Ser Lys Leu Thr Glu Pro Ala Ser Val Pro Ile
                 365                 370                 375

 His Lys Leu Ser Val Ser Asn Met Val His Thr Ala Lys Lys Lys
                 380                 385                 390

 Ile Arg Lys His Arg Gly Val Glu Glu Ser Pro Leu Asn Asn Asp
                 395                 400                 405

 Val Leu Asn Thr Ile Leu Leu Phe Leu Phe Pro Asp Ala Val Ser
                 410                 415                 420

 Glu Lys Pro Leu Asp Gly Thr Thr Ser Thr Asp Asn Asn Asn Pro
                 425                 430                 435

 Pro Ser Glu Ser Glu Asp Tyr Asn Leu Tyr Asn Gln Phe Lys Ser
                 440                 445                 450

 Ala Pro Ser Asp Ser Leu Thr Tyr Lys Leu Ala Leu Cys Leu Cys
                 455                 460                 465

 Met Ile Asn Phe Tyr His Gly Gly Leu Lys Gly Val Ala His Leu
                 470                 475                 480

 Trp Gln Glu Phe Val Leu Glu Met Arg Phe Arg Trp Glu Asn Asn
                 485                 490                 495

 Phe Leu Ile Pro Gly Leu Ala Ser Gly Pro Pro Asp Leu Arg Cys
                 500                 505                 510

 Cys Leu Leu His Gln Lys Leu Gln Met Leu Asn Cys Cys Ile Glu
                 515                 520                 525

 Arg Lys Lys Ala Arg Asp Glu Gly Lys Lys Thr Ser Ala Ser Asp
                 530                 535                 540

 Val Thr Asn Ile Tyr Pro Gly Asp Ala Gly Lys Ala Gly Asp Gln
                 545                 550                 555

 Leu Val Pro Asp Asn Leu Lys Glu Thr Asp Lys Glu Lys Gly Glu
                 560                 565                 570

 Val Gly Lys Ser Trp Asp Ser Trp Ser Asp Ser Glu Glu Glu Phe
                 575                 580                 585

 Phe Glu Cys Leu Ser Asp Thr Glu Glu Leu Lys Gly Asn Gly Gln
                 590                 595                 600

 Glu Ser Gly Lys Lys Gly Gly Pro Lys Glu Met Ala Asn Leu Arg
                 605                 610                 615

 Pro Glu Gly Arg Leu Tyr Gln His Gly Lys Leu Thr Leu Leu His
                 620                 625                 630

 Asn Gly Glu Pro Leu Tyr Ile Pro Val Thr Gln Glu Pro Ala Pro
                 635                 640                 645

 Met Thr Glu Asp Leu Leu Glu Glu Gln Ser Glu Val Leu Ala Lys
                 650                 655                 660

 Leu Gly Thr Ser Ala Glu Gly Ala His Leu Arg Ala Arg Met Gln
                 665                 670                 675

 Ser Ala Cys Leu Leu Ser Asp Met Glu Ser Phe Lys Ala Ala Asn
                 680                 685                 690

 Pro Gly Cys Ser Leu Glu Asp Phe Val Arg Trp Tyr Ser Pro Arg
                 695                 700                 705

 Asp Tyr Ile Glu Glu Glu Val Ile Asp Glu Lys Gly Asn Val Val
                 710                 715                 720

 Leu Lys Gly Glu Leu Ser Ala Arg Met Lys Ile Pro Ser Asn Met
                 725                 730                 735

 Trp Val Glu Ala Trp Glu Thr Ala Lys Pro Ile Pro Ala Arg Arg
                 740                 745                 750

 Gln Arg Arg Leu Phe Asp Asp Thr Arg Glu Ala Glu Lys Val Leu
                 755                 760                 765

 His Tyr Leu Ala Ile Gln Lys Pro Ala Asp Leu Ala Arg His Leu
                 770                 775                 780

 Leu Pro Cys Val Ile His Ala Ala Val Leu Lys Val Lys Glu Glu
                 785                 790                 795

 Glu Ser Leu Glu Asn Ile Ser Ser Val Lys Lys Ile Ile Lys Gln
                 800                 805                 810

 Ile Ile Ser His Ser Ser Lys Val Leu His Phe Pro Asn Pro Glu
                 815                 820                 825

 Asp Lys Lys Leu Glu Glu Ile Ile His Gln Ile Thr Asn Val Glu
                 830                 835                 840

 Ala Leu Ile Ala Arg Ala Arg Ser Leu Lys Ala Lys Phe Gly Thr
                 845                 850                 855

 Glu Lys Cys Glu Gln Glu Glu Glu Lys Glu Asp Leu Glu Arg Phe
                 860                 865                 870

 Val Ser Cys Leu Leu Glu Gln Pro Glu Val Leu Val Thr Gly Ala
                 875                 880                 885

 Gly Arg Gly His Ala Gly Arg Ile Ile His Lys Leu Phe Val Asn
                 890                 895                 900

 Ala Gln Arg Ala Ala Ala Met Thr Pro Pro Glu Glu Glu Leu Lys
                 905                 910                 915

 Arg Met Gly Ser Pro Glu Glu Arg Arg Gln Asn Ser Val Ser Asp
                 920                 925                 930

 Phe Pro Pro Pro Ala Gly Arg Glu Phe Ile Leu Arg Thr Thr Val
                 935                 940                 945

 Pro Arg Pro Ala Pro Tyr Ser Lys Ala Leu Pro Gln Arg Met Tyr
                 950                 955                 960

 Ser Val Leu Thr Lys Glu Asp Phe Arg Leu Ala Gly Ala Phe Ser
                 965                 970                 975

 Ser Asp Thr Ser Phe Phe
                 980

<210> 2697
<211> 2836
<212> DNA
<213> Homo sapien

<400> 2697
 acgtcacgcg gccgttacgg cgctcaggcg tctcgacgcg cgcgatttaa 50

 aaccagctca ggagacgcca aggaaagatg ggacctcccg gcccagcact 100

 gccagccaca atgaataact cttcttcaga gacgcgagga cacccccaca 150

 gtgcctcctc tccttcagag cgtgtgttcc cgatgcccct gcccaggaag 200

 gcgcctctca atattcctgg caccccagtc ctcgaagact ttcctcagaa 250

 tgacgatgag aaggagcggc tgcagcggag gcgctcgagg gtctttgatc 300

 tgcagttcag cactgactca cctcgcttat tggcctcccc ctccagcagg 350

 agtattgaca tttcagctac tatccccaag tttacaaaca cgcagattac 400

 ggaacattac tccacctgta tcaaactgtc cactgaaaat aaaatcacta 450

 ccaagaatgc ttttggtttg cacttgattg attttatgtc agagattctt 500

 aaacagaaag acaccgaacc aaccaacttt aaagtggctg cgggtactct 550

 ggatgccagc accaagatct atgctgtgcg cgtggatgcc gtccatgccg 600

 atgtatacag agtccttggg gggctgggca aagatgcacc gtctttggaa 650

 gaagtagaag gccatgttgc tgatggaagt gctactgaaa tgggaacaac 700

 caaaaaggct gtaaagccaa agaagaagca cttacacaga actattgagc 750

 agaacataaa caacctcaat gtctccgaag cagatcggaa gtgtgagatt 800

 gatcccatgt ttcagaagac agcagcctca tttgatgagt gcagcacagc 850

 aggggtgttt ctgtccactc tccactgcca ggactacaga agtgaactgc 900

 tgtttccctc tgatgtccag actctctcca cgggagaacc tctcgagttg 950

 ccagagttag gttgtgtaga aatgacagat ttaaaagcgc ccttgcagca 1000

 gtgtgcagaa gatcgccaga tctgcccttc cctggccggg ttccagttta 1050

 cacagtggga cagtgaaaca cataatgagt ctgtgtcggc cctggtagac 1100

 aagtttaaga agaatgacca ggtatttgac atcaatgctg aagttgacga 1150

 gagtgactgt ggagacttcc ccgatgggtc cctgggggat gactttgatg 1200

 ccaacgatga acctgaccac accgcagttg gggatcatga agagttcagg 1250

 agctggaagg agccctgcca ggttcagagc tgccaggaag aaatgatttc 1300

 ccttggggat ggagacatca ggaccatgtg cccccttctg tctatgaaac 1350

 ctggagaata ttcttatttc agtcctcgga ccatgtcgat gtgggctggc 1400

 ccggatcact ggcgctttag gcctcgacgc aaacaagatg ctccttccca 1450

 atcagaaaac aaaaagaaga gtacaaaaaa agattttgaa attgactttg 1500

 aagatgatat tgactttgat gtatatttta gaaaaacaaa ggctgctact 1550

 attctgacca agtccacttt ggagaaccag aattggagag ctaccaccct 1600

 tcctacagat ttcaactaca atgttgacac tctggtccag cttcacctca 1650

 aaccaggcac caggttactt aagatggccc agggccatag ggtagagact 1700

 gagcattatg aagaaattga agactatgat tacaacaacc ctaacgacac 1750

 ctccaacttt tgccctggat tacaggctgc tgacagtgat gatgaagatt 1800

 tggatgactt atttgtggga cctgttggga actctgacct ctcaccttat 1850

 ccttgccatc cacctaagac agcacaacag aatggtgaca ctccagaagc 1900

 ccaaggatta gacatcacaa catatgggga gtcaaacttg gtagctgagc 1950

 ctcagaaggt aaataaaatt gaaattcact atgccaagac tgccaaaaag 2000

 atggacatga agaaactgaa gcagagcatg tggagtctgc tgacagcgct 2050

 ctccggaaag gaggcagatg cagaggcaaa ccacagggaa gctggaaaag 2100

 aagcggccct ggcagaagtg gctgacgaga agatgcttag cgggctcacg 2150

 aaggacctgc agaggagcct gccccctgtc atggctcaga acctctccat 2200

 acctctggct tttgcctgtc tcctacattt agccaatgaa aagaatctaa 2250

 aactggaagg aacagaggac ctctctgatg ttcttgtgag gcaaggagat 2300

 tgagttcact atggagaagt cagcagcagg aggcccatcc cttactcagt 2350

 tgccgggaca tccccagtct cgggggaaga agatgccatg ggcttatacc 2400

 caggctgtag ccaactacca acgtgcctgt ttgtttgttg ctctttcctt 2450

 ctctccatca tagtctgggt gccagcgccc tgaagctccg tgctcaactg 2500

 attaaacttt actgccctat ggtgaccatc taggagaggg gagggcagag 2550

 ggggtgaggg tactattctg gattgagaaa acctatatcc attctttata 2600

 tcaatgtata gttttagtct cctaaattga tctgttattt tccaaactat 2650

 tctcttgtag aaaattttcc agtgggcact taatggtgcc cttgaagaac 2700

 ttcctaatcc atgtacataa aatacatcat atgtacactt ataaatgtat 2750

 atagaatgct caaaaataaa attcttaata atagaactgg caaaataaaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 2836

<210> 2698
<211> 741
<212> PRT
<213> Homo sapien

<400> 2698
 Met Gly Pro Pro Gly Pro Ala Leu Pro Ala Thr Met Asn Asn Ser
   1               5                  10                  15

 Ser Ser Glu Thr Arg Gly His Pro His Ser Ala Ser Ser Pro Ser
                  20                  25                  30

 Glu Arg Val Phe Pro Met Pro Leu Pro Arg Lys Ala Pro Leu Asn
                  35                  40                  45

 Ile Pro Gly Thr Pro Val Leu Glu Asp Phe Pro Gln Asn Asp Asp
                  50                  55                  60

 Glu Lys Glu Arg Leu Gln Arg Arg Arg Ser Arg Val Phe Asp Leu
                  65                  70                  75

 Gln Phe Ser Thr Asp Ser Pro Arg Leu Leu Ala Ser Pro Ser Ser
                  80                  85                  90

 Arg Ser Ile Asp Ile Ser Ala Thr Ile Pro Lys Phe Thr Asn Thr
                  95                 100                 105

 Gln Ile Thr Glu His Tyr Ser Thr Cys Ile Lys Leu Ser Thr Glu
                 110                 115                 120

 Asn Lys Ile Thr Thr Lys Asn Ala Phe Gly Leu His Leu Ile Asp
                 125                 130                 135

 Phe Met Ser Glu Ile Leu Lys Gln Lys Asp Thr Glu Pro Thr Asn
                 140                 145                 150

 Phe Lys Val Ala Ala Gly Thr Leu Asp Ala Ser Thr Lys Ile Tyr
                 155                 160                 165

 Ala Val Arg Val Asp Ala Val His Ala Asp Val Tyr Arg Val Leu
                 170                 175                 180

 Gly Gly Leu Gly Lys Asp Ala Pro Ser Leu Glu Glu Val Glu Gly
                 185                 190                 195

 His Val Ala Asp Gly Ser Ala Thr Glu Met Gly Thr Thr Lys Lys
                 200                 205                 210

 Ala Val Lys Pro Lys Lys Lys His Leu His Arg Thr Ile Glu Gln
                 215                 220                 225

 Asn Ile Asn Asn Leu Asn Val Ser Glu Ala Asp Arg Lys Cys Glu
                 230                 235                 240

 Ile Asp Pro Met Phe Gln Lys Thr Ala Ala Ser Phe Asp Glu Cys
                 245                 250                 255

 Ser Thr Ala Gly Val Phe Leu Ser Thr Leu His Cys Gln Asp Tyr
                 260                 265                 270

 Arg Ser Glu Leu Leu Phe Pro Ser Asp Val Gln Thr Leu Ser Thr
                 275                 280                 285

 Gly Glu Pro Leu Glu Leu Pro Glu Leu Gly Cys Val Glu Met Thr
                 290                 295                 300

 Asp Leu Lys Ala Pro Leu Gln Gln Cys Ala Glu Asp Arg Gln Ile
                 305                 310                 315

 Cys Pro Ser Leu Ala Gly Phe Gln Phe Thr Gln Trp Asp Ser Glu
                 320                 325                 330

 Thr His Asn Glu Ser Val Ser Ala Leu Val Asp Lys Phe Lys Lys
                 335                 340                 345

 Asn Asp Gln Val Phe Asp Ile Asn Ala Glu Val Asp Glu Ser Asp
                 350                 355                 360

 Cys Gly Asp Phe Pro Asp Gly Ser Leu Gly Asp Asp Phe Asp Ala
                 365                 370                 375

 Asn Asp Glu Pro Asp His Thr Ala Val Gly Asp His Glu Glu Phe
                 380                 385                 390

 Arg Ser Trp Lys Glu Pro Cys Gln Val Gln Ser Cys Gln Glu Glu
                 395                 400                 405

 Met Ile Ser Leu Gly Asp Gly Asp Ile Arg Thr Met Cys Pro Leu
                 410                 415                 420

 Leu Ser Met Lys Pro Gly Glu Tyr Ser Tyr Phe Ser Pro Arg Thr
                 425                 430                 435

 Met Ser Met Trp Ala Gly Pro Asp His Trp Arg Phe Arg Pro Arg
                 440                 445                 450

 Arg Lys Gln Asp Ala Pro Ser Gln Ser Glu Asn Lys Lys Lys Ser
                 455                 460                 465

 Thr Lys Lys Asp Phe Glu Ile Asp Phe Glu Asp Asp Ile Asp Phe
                 470                 475                 480

 Asp Val Tyr Phe Arg Lys Thr Lys Ala Ala Thr Ile Leu Thr Lys
                 485                 490                 495

 Ser Thr Leu Glu Asn Gln Asn Trp Arg Ala Thr Thr Leu Pro Thr
                 500                 505                 510

 Asp Phe Asn Tyr Asn Val Asp Thr Leu Val Gln Leu His Leu Lys
                 515                 520                 525

 Pro Gly Thr Arg Leu Leu Lys Met Ala Gln Gly His Arg Val Glu
                 530                 535                 540

 Thr Glu His Tyr Glu Glu Ile Glu Asp Tyr Asp Tyr Asn Asn Pro
                 545                 550                 555

 Asn Asp Thr Ser Asn Phe Cys Pro Gly Leu Gln Ala Ala Asp Ser
                 560                 565                 570

 Asp Asp Glu Asp Leu Asp Asp Leu Phe Val Gly Pro Val Gly Asn
                 575                 580                 585

 Ser Asp Leu Ser Pro Tyr Pro Cys His Pro Pro Lys Thr Ala Gln
                 590                 595                 600

 Gln Asn Gly Asp Thr Pro Glu Ala Gln Gly Leu Asp Ile Thr Thr
                 605                 610                 615

 Tyr Gly Glu Ser Asn Leu Val Ala Glu Pro Gln Lys Val Asn Lys
                 620                 625                 630

 Ile Glu Ile His Tyr Ala Lys Thr Ala Lys Lys Met Asp Met Lys
                 635                 640                 645

 Lys Leu Lys Gln Ser Met Trp Ser Leu Leu Thr Ala Leu Ser Gly
                 650                 655                 660

 Lys Glu Ala Asp Ala Glu Ala Asn His Arg Glu Ala Gly Lys Glu
                 665                 670                 675

 Ala Ala Leu Ala Glu Val Ala Asp Glu Lys Met Leu Ser Gly Leu
                 680                 685                 690

 Thr Lys Asp Leu Gln Arg Ser Leu Pro Pro Val Met Ala Gln Asn
                 695                 700                 705

 Leu Ser Ile Pro Leu Ala Phe Ala Cys Leu Leu His Leu Ala Asn
                 710                 715                 720

 Glu Lys Asn Leu Lys Leu Glu Gly Thr Glu Asp Leu Ser Asp Val
                 725                 730                 735

 Leu Val Arg Gln Gly Asp
                 740

<210> 2699
<211> 2428
<212> DNA
<213> Homo sapien

<400> 2699
 cccacgcgtc cggtctttga tgaagttgat acagatcaat ctggtgtctt 50

 gtctgacaga gaaatccgaa cactggctac cagaattcac gaactgccgt 100

 taagtttgca ggatttgaca ggtctggaac acatgctaat aaattgctca 150

 aaaatgcttc ctgctgatat cacgcagcta aataatattc caccaactca 200

 ggaatcctac tatgatccca acctgccacc ggtcactaaa agtctagtaa 250

 caaactgtaa accagtaact gacaaaatcc acaaagcata taaggacaaa 300

 aacaaatata ggtttgaaat catgggagaa gaagaaatcg cttttaaaat 350

 gattcgtacc aacgtttctc atgtggttgg ccagttggat gacataagaa 400

 aaaaccctag gaagtttgtt tgcctgaatg acaacattga ccacaatcat 450

 aaagatgctc agacagtgaa ggctgttctc agggacttct atgaatccat 500

 gttccccata ccttcccaat ttgaactgcc aagagagtat cgaaaccgtt 550

 tccttcatat gcatgagctg caggaatgga gggcttatcg agacaaattg 600

 aagttttgga cccattgtgt actagcaaca ttgattatgt ttactatatt 650

 ctcatttttt gctgagcagt taattgcact taagcggaag atatttccca 700

 gaaggaggat acacaaagaa gctagtccca atcgaatcag agtatagaag 750

 atcttcattt gaaaaccatc tacctcagca tttactgagc attttaaaac 800

 tcagcttcac agagatgtct ttgtgatgtg atgcttagca gtttggcccg 850

 aagaaggaaa atatccagta ccatgctgtt ttgtggcatg aatatagccc 900

 actgaccagg aattatttaa ccaacccact gaaaacttgt gtgttgagca 950

 gctctgaact gattttactt ttaaagaatt tgctcatgga cctgtcatcc 1000

 tttttataaa aaggctcact gacaagagac agctgttaat ttcccacagc 1050

 aatcattgca gactaacttt attaggagaa gcctatgcca gctgggagtg 1100

 attgctaaga ggctccagtc tttgcattcc aaagcctttt gctaaagttt 1150

 tgcacttttt ttttttcatt tcccattttt aagtagttac taagttaact 1200

 agttattctt gcttctgagt ataacgaatt gggatgtcta aacctatttt 1250

 tatagatgtt atttaaataa tgcagcaata tcacctctta ttgacaatac 1300

 ctaaattatg agttttatta atatttaaga ctgtaaatgg tcttaaacca 1350

 ctaactactg aagagctcaa tgattgacat ctgaaatgct ttgtaattat 1400

 tgacttcagc ccctaagaat gctatgattt cacgtgcagg tctaatttca 1450

 aagggctaga gttagtacta cttaccagat gtaattatgt tttggaaatg 1500

 tacatattca aacagaagtg cctcatttta gaaatgagta gtgctgatgg 1550

 cactggcaca ttacagtggt gtcttgttta atactcattg gtatattcca 1600

 gtagctatct ctctcagttg gtttttgata gaacagaggc cagcaaactt 1650

 tctttgtaaa aggctggtta gtaaattatt gcaggccacc tgtgtctttg 1700

 tcatacattc ttcttgctgt tgtttagttt gttttttttc aaacaaccct 1750

 ctaaaaatgt aaaaaccatg tttagcttgc agctgtacaa aaactgccca 1800

 ccagccagat gtgaccctca ggccatcatt tgccaatcac tgagaattag 1850

 tttttgttgt tgttgttgtt gttgtttttg agacagagtc tctctctgtt 1900

 gcccaggctg gagtgcagtg gcgcaatctc agctcactgc aacctccgcc 1950

 tcccgggttc aagcagttct gtctcagcct tctgagtagc tgggactaca 2000

 ggtgcatgcc accacaccct gctaattttt gtatttttag tagagacggg 2050

 ggttccacca tattggtcag gcttatcttg aactcctgac ctcaggtgat 2100

 ccacctgcct ctgcctccca aagtgctgag attacaggca taagccagtg 2150

 cacccagccg agaattagta tttttatgta tggttaaacc ttggcgtcta 2200

 gccatatttt atgtcataat acaatggatt tgtgaagagc agattccatg 2250

 agtaactctg acaggtattt tagatcatga tctcaacaat attcttccaa 2300

 aatggcatac atcttttgta caaagaactt gaaatgtaaa tactgtgttt 2350

 gtgctgtaag agttgtgtat ttcaaaaact gaaatctcat aaaaagttaa 2400

 atttttgtct gaaaaaaaaa aaaaaaaa 2428

<210> 2700
<211> 1327
<212> DNA
<213> Homo sapien

<400> 2700
 gtacgttcct catgaaaggg acgacgggag ctgcatgaaa gccgaagtta 50

 tggaccgcta gcatctgtca ctggccaccg gtttccggga gtaagcggca 100

 gctaccttac agccctgaca cgagccgggt gctctctctt ctcaccgcgg 150

 cccacgtctc ctcgctggct ccggtggcct cgctgggtcg cgaggaggcg 200

 gaggactgta ctctgaggcc aaaagccaga gtcggccctg aacgcccacg 250

 actctcaggg tccagaggcc gtgagaccgg ccgcggctga aaggtaaaga 300

 aaccaagtgg aagagtgttt cctcctctgg ccgtaaagca gctgtccccg 350

 ccctactccg gaccgcccca aagactccat gggatggacc tgagtcagcc 400

 gaatcctagc cccttccctt gggcctgctg tggtgctcga catcagtgac 450

 agacggaagc agcagaccat caaggctacg ggaggcccgg ggcgcttgcg 500

 aagatgaagt ttggctgcct ctccttccgg cagccttatg ctggctttgt 550

 cttaaatgga atcaagactg tggagacgcg ctggcgtcct ctgctgagca 600

 gccagcggaa ctgtaccatc gccgtccaca ttgctcacag ggactgggaa 650

 ggcgatgcct gtcgggagct gctggtggag agactcggga tgactcctgc 700

 tcagattcag gccttgctca ggaaagggga aaagtttggt cgaggagtga 750

 tagcgggact cgttgacatt ggggaaactt tgcaatgccc cgaagactta 800

 actcccgatg aggttgtgga actagaaaat caagctgcac tgaccaacct 850

 gaagcagaag tacctgactg tgatttcaaa ccccaggtgg ttactggagc 900

 ccatacctag gaaaggaggc aaggatgtat tccaggtaga catcccagag 950

 cacctgatcc ctttggggca tgaagtgtga caagtgtggg ctcctgaaag 1000

 gaatgttcca gagaaaccag ctaaatcatg gcaccttcaa tttgccatcg 1050

 tgacgcagac ctgtataaat taggttaaag atgaatttcc actgctttgg 1100

 agagtcccac ccactaagca ctgtgcatgt aaacaggttc ctttgctcag 1150

 atgaaggaag tagggggtgg ggctttcctt gtgtgatgcc tccttaggca 1200

 cacaggcaat gtctcaagta ctttgacctt agggtagaag gcaaagctgc 1250

 cagtaaatgt ctcagcattg ctgctaattt tggtcctgct agtttctgga 1300

 ttgtacaaat aaatgtgttg tagatga 1327

<210> 2701
<211> 158
<212> PRT
<213> Homo sapien

<400> 2701
 Met Lys Phe Gly Cys Leu Ser Phe Arg Gln Pro Tyr Ala Gly Phe
   1               5                  10                  15

 Val Leu Asn Gly Ile Lys Thr Val Glu Thr Arg Trp Arg Pro Leu
                  20                  25                  30

 Leu Ser Ser Gln Arg Asn Cys Thr Ile Ala Val His Ile Ala His
                  35                  40                  45

 Arg Asp Trp Glu Gly Asp Ala Cys Arg Glu Leu Leu Val Glu Arg
                  50                  55                  60

 Leu Gly Met Thr Pro Ala Gln Ile Gln Ala Leu Leu Arg Lys Gly
                  65                  70                  75

 Glu Lys Phe Gly Arg Gly Val Ile Ala Gly Leu Val Asp Ile Gly
                  80                  85                  90

 Glu Thr Leu Gln Cys Pro Glu Asp Leu Thr Pro Asp Glu Val Val
                  95                 100                 105

 Glu Leu Glu Asn Gln Ala Ala Leu Thr Asn Leu Lys Gln Lys Tyr
                 110                 115                 120

 Leu Thr Val Ile Ser Asn Pro Arg Trp Leu Leu Glu Pro Ile Pro
                 125                 130                 135

 Arg Lys Gly Gly Lys Asp Val Phe Gln Val Asp Ile Pro Glu His
                 140                 145                 150

 Leu Ile Pro Leu Gly His Glu Val
                 155

<210> 2702
<211> 2524
<212> DNA
<213> Homo sapien

<400> 2702
 ccggggcggc ggttgcatca gattctagga agtgtctgta gccgcagctg 50

 cgggtccggg attcccagcc atggcagatt cctccgggca gcagggcaaa 100

 ggccggcgtg tgcagcccca gtggtcccct cctgctggga cccagccatg 150

 cagactccac ctttacaaca gcctcaccag gaacaaggaa gtgttcatac 200

 ctcaagatgg gaaaaaggtg acgtggtatt gctgtgggcc aaccgtctat 250

 gacgcatctc acatggggca cgccaggtcc tacatctctt ttgatatctt 300

 gagaagagtg ttgaaggatt acttcaaatt tgatgtcttt tattgcatga 350

 acattacgga tattgatgac aagatcatca agagggcccg gcagaaccac 400

 ctgttcgagc agtatcggga gaagaggcct gaagcggcac agctcttgga 450

 ggatgttcag gccgccctga agccattttc agtaaaatta aatgagacca 500

 cggatcccga taaaaagcag atgctcgaac ggattcagca cgcagtgcag 550

 cttgccacag agccacttga gaaagctgtg cagtccagac tcacgggaga 600

 ggaagtcaac agctgtgtgg aggtgttgct ggaagaagcc aaggatttgc 650

 tctctgactg gctggattct acacttggct gtgatgtcac tgacaattcc 700

 atcttctcca agctgcccaa gttctgggag ggggacttcc acagagacat 750

 ggaagctctg aatgttctcc ctccagatgt cttaacccgg gttagtgagt 800

 atgtgccaga aattgtgaac tttgtccaga agattgtgga caacggttac 850

 ggctatgtct ccaatgggtc tgtctacttt gatacagcga agtttgcttc 900

 tagcgagaag cactcctatg ggaagctggt gcctgaggcc gttggagatc 950

 agaaagccct tcaagaaggg gaaggtgacc tgagcatctc tgcagaccgc 1000

 ctgagtgaga agcgctctcc caacgacttt gccttatgga aggcctctaa 1050

 gcccggagaa ccgtcctggc cgtgcccttg gggaaagggt cgtccgggct 1100

 ggcatatcga gtgctcggcc atggcaggca ccctcctagg ggcttcgatg 1150

 gacattcacg gaggtgggtt cgacctccgg ttcccccacc atgacaatga 1200

 gctggcacag tcggaggcct actttgaaaa cgactgctgg gtcaggtact 1250

 tcctgcacac aggccacctg accattgcag gctgcaaaat gtcaaagtca 1300

 ctaaaaaact tcatcaccat taaagatgcc ttgaaaaagc actcagcacg 1350

 gcagttgcgg ctggccttcc tcatgcactc gtggaaggac accctggact 1400

 actccagcaa caccatggag tcagcgcttc aatatgagaa gttcttgaat 1450

 gagtttttct taaatgtgaa agatatcctt cgcgctcctg ttgacatcac 1500

 tggtcagttt gagaagtggg gagaagaaga agcagaactg aataagaact 1550

 tttatgacaa gaagacagca attcacaaag ccctctgtga caatgttgac 1600

 acccgcaccg tcatggaaga gatgcgggcc ttggtcagtc agtgcaacct 1650

 ctatatggca gcccggaaag ccgtgaggaa gaggcccaac caggctctgc 1700

 tggagaacat cgccctgtac ctcacccata tgctgaagat ctttggggcc 1750

 gtagaagagg acagctccct gggattcccg gtcggagggc ctggaaccag 1800

 cctcagtctc gaggccacag tcatgcccta ccttcaggtg ttatcagaat 1850

 tccgagaagg agtgcggaag attgcccgag agcaaaaagt ccctgagatt 1900

 ctgcagctca gcgatgccct gcgggacaac atcctgcctg agcttggggt 1950

 gcggtttgaa gaccacgaag gactgcccac agtggtgaaa ctggtagaca 2000

 gaaacacctt attaaaagag agagaagaaa agagacgggt tgaagaggag 2050

 aagaggaaga agaaagagga ggcggcccgg aggaaacagg aacaagaagc 2100

 agcaaagctg gccaagatga agattccccc cagtgagatg ttcttgtcag 2150

 aaaccgacaa atactccaag tttgatgaaa atggtctgcc cacacatgac 2200

 atggagggca aagagctcag caaagggcaa gccaagaagc tgaagaagct 2250

 cttcgaggct caggagaagc tctacaagga atatctgcag atggcccaga 2300

 atggaagctt ccagtgaggg ggcacaggac tgacttttta aaccattgtg 2350

 gactagtggc tgctgtctgc ctcagtgaca atgtcccagc gctcctatca 2400

 tgtttacagt cacccttggg tcctaaatta agagttgtgt tcatgtaggt 2450

 tcgtgtcgtc gttggctctg agacattgat aataaatttt tctcaacagt 2500

 gaaaaaaaaa aaaaaaaaaa aaaa 2524

<210> 2703
<211> 748
<212> PRT
<213> Homo sapien

<400> 2703
 Met Ala Asp Ser Ser Gly Gln Gln Gly Lys Gly Arg Arg Val Gln
   1               5                  10                  15

 Pro Gln Trp Ser Pro Pro Ala Gly Thr Gln Pro Cys Arg Leu His
                  20                  25                  30

 Leu Tyr Asn Ser Leu Thr Arg Asn Lys Glu Val Phe Ile Pro Gln
                  35                  40                  45

 Asp Gly Lys Lys Val Thr Trp Tyr Cys Cys Gly Pro Thr Val Tyr
                  50                  55                  60

 Asp Ala Ser His Met Gly His Ala Arg Ser Tyr Ile Ser Phe Asp
                  65                  70                  75

 Ile Leu Arg Arg Val Leu Lys Asp Tyr Phe Lys Phe Asp Val Phe
                  80                  85                  90

 Tyr Cys Met Asn Ile Thr Asp Ile Asp Asp Lys Ile Ile Lys Arg
                  95                 100                 105

 Ala Arg Gln Asn His Leu Phe Glu Gln Tyr Arg Glu Lys Arg Pro
                 110                 115                 120

 Glu Ala Ala Gln Leu Leu Glu Asp Val Gln Ala Ala Leu Lys Pro
                 125                 130                 135

 Phe Ser Val Lys Leu Asn Glu Thr Thr Asp Pro Asp Lys Lys Gln
                 140                 145                 150

 Met Leu Glu Arg Ile Gln His Ala Val Gln Leu Ala Thr Glu Pro
                 155                 160                 165

 Leu Glu Lys Ala Val Gln Ser Arg Leu Thr Gly Glu Glu Val Asn
                 170                 175                 180

 Ser Cys Val Glu Val Leu Leu Glu Glu Ala Lys Asp Leu Leu Ser
                 185                 190                 195

 Asp Trp Leu Asp Ser Thr Leu Gly Cys Asp Val Thr Asp Asn Ser
                 200                 205                 210

 Ile Phe Ser Lys Leu Pro Lys Phe Trp Glu Gly Asp Phe His Arg
                 215                 220                 225

 Asp Met Glu Ala Leu Asn Val Leu Pro Pro Asp Val Leu Thr Arg
                 230                 235                 240

 Val Ser Glu Tyr Val Pro Glu Ile Val Asn Phe Val Gln Lys Ile
                 245                 250                 255

 Val Asp Asn Gly Tyr Gly Tyr Val Ser Asn Gly Ser Val Tyr Phe
                 260                 265                 270

 Asp Thr Ala Lys Phe Ala Ser Ser Glu Lys His Ser Tyr Gly Lys
                 275                 280                 285

 Leu Val Pro Glu Ala Val Gly Asp Gln Lys Ala Leu Gln Glu Gly
                 290                 295                 300

 Glu Gly Asp Leu Ser Ile Ser Ala Asp Arg Leu Ser Glu Lys Arg
                 305                 310                 315

 Ser Pro Asn Asp Phe Ala Leu Trp Lys Ala Ser Lys Pro Gly Glu
                 320                 325                 330

 Pro Ser Trp Pro Cys Pro Trp Gly Lys Gly Arg Pro Gly Trp His
                 335                 340                 345

 Ile Glu Cys Ser Ala Met Ala Gly Thr Leu Leu Gly Ala Ser Met
                 350                 355                 360

 Asp Ile His Gly Gly Gly Phe Asp Leu Arg Phe Pro His His Asp
                 365                 370                 375

 Asn Glu Leu Ala Gln Ser Glu Ala Tyr Phe Glu Asn Asp Cys Trp
                 380                 385                 390

 Val Arg Tyr Phe Leu His Thr Gly His Leu Thr Ile Ala Gly Cys
                 395                 400                 405

 Lys Met Ser Lys Ser Leu Lys Asn Phe Ile Thr Ile Lys Asp Ala
                 410                 415                 420

 Leu Lys Lys His Ser Ala Arg Gln Leu Arg Leu Ala Phe Leu Met
                 425                 430                 435

 His Ser Trp Lys Asp Thr Leu Asp Tyr Ser Ser Asn Thr Met Glu
                 440                 445                 450

 Ser Ala Leu Gln Tyr Glu Lys Phe Leu Asn Glu Phe Phe Leu Asn
                 455                 460                 465

 Val Lys Asp Ile Leu Arg Ala Pro Val Asp Ile Thr Gly Gln Phe
                 470                 475                 480

 Glu Lys Trp Gly Glu Glu Glu Ala Glu Leu Asn Lys Asn Phe Tyr
                 485                 490                 495

 Asp Lys Lys Thr Ala Ile His Lys Ala Leu Cys Asp Asn Val Asp
                 500                 505                 510

 Thr Arg Thr Val Met Glu Glu Met Arg Ala Leu Val Ser Gln Cys
                 515                 520                 525

 Asn Leu Tyr Met Ala Ala Arg Lys Ala Val Arg Lys Arg Pro Asn
                 530                 535                 540

 Gln Ala Leu Leu Glu Asn Ile Ala Leu Tyr Leu Thr His Met Leu
                 545                 550                 555

 Lys Ile Phe Gly Ala Val Glu Glu Asp Ser Ser Leu Gly Phe Pro
                 560                 565                 570

 Val Gly Gly Pro Gly Thr Ser Leu Ser Leu Glu Ala Thr Val Met
                 575                 580                 585

 Pro Tyr Leu Gln Val Leu Ser Glu Phe Arg Glu Gly Val Arg Lys
                 590                 595                 600

 Ile Ala Arg Glu Gln Lys Val Pro Glu Ile Leu Gln Leu Ser Asp
                 605                 610                 615

 Ala Leu Arg Asp Asn Ile Leu Pro Glu Leu Gly Val Arg Phe Glu
                 620                 625                 630

 Asp His Glu Gly Leu Pro Thr Val Val Lys Leu Val Asp Arg Asn
                 635                 640                 645

 Thr Leu Leu Lys Glu Arg Glu Glu Lys Arg Arg Val Glu Glu Glu
                 650                 655                 660

 Lys Arg Lys Lys Lys Glu Glu Ala Ala Arg Arg Lys Gln Glu Gln
                 665                 670                 675

 Glu Ala Ala Lys Leu Ala Lys Met Lys Ile Pro Pro Ser Glu Met
                 680                 685                 690

 Phe Leu Ser Glu Thr Asp Lys Tyr Ser Lys Phe Asp Glu Asn Gly
                 695                 700                 705

 Leu Pro Thr His Asp Met Glu Gly Lys Glu Leu Ser Lys Gly Gln
                 710                 715                 720

 Ala Lys Lys Leu Lys Lys Leu Phe Glu Ala Gln Glu Lys Leu Tyr
                 725                 730                 735

 Lys Glu Tyr Leu Gln Met Ala Gln Asn Gly Ser Phe Gln
                 740                 745

<210> 2704
<211> 6703
<212> DNA
<213> Homo sapien

<400> 2704
 cgcacgctgc caaagcctgg agaagtggaa tctcgtcagc gccgctccct 50

 gcgcgggact cgcggaacgg cactgagcat gctcagttgc cggagcccgt 100

 tctggtctca agtaggaagc tagtgcgctg taaccgcatc tgatctgggc 150

 gctccgggaa gggcgagact ggagcagagc cgctgggcgc cggagccgag 200

 gcgagcgccg cgcgcaccac tggttggagt tgctgtgggt gagctgctgt 250

 ggtctgtagc caagcatgct gtggtcggat ctgcccagcc gtggaacaga 300

 aacatttgct ggatggaaaa tccataaaag aaagctcctg tgaaaagctg 350

 aggctgacaa taatttaagc aaaatcagat cgatctcttt gggctgcctg 400

 acctccttgg gtgcttgcta ttaattaaca gactttgtgg ggaaaaaaag 450

 gagcttgcct tctgagcttt gtaccaaaga cctgggaaaa ctaaccatct 500

 cagtctttcc tgaggacttg ggaactgccg aggcctctgc caatgtgttg 550

 actgtcgcta tgggctcact gttgtccagg cagctcatat ttcaaattat 600

 aacctatttc ctgcaccatt gctgacgcct ggtgatccat gtcagaagta 650

 cttccagctg actcaggtgt tgacaccttg gcagtgttta tggccagcag 700

 cggaactaca gacgtcacaa atcggaacag cccagccaca ccaccaaaca 750

 cccttaacct ccgatcctcc cacaatgaac tgttgaacgc tgaaataaaa 800

 cacacagaaa ccaagaacag cacacctccc aaatgcagga aaaaatatgc 850

 actaactaac atccaggcgg ccatgggcct ctcggatcca gctgcacagc 900

 ccctgctggg aaatggctct gccaacatca agctggtgaa aaatggggag 950

 aaccagctcc gtaaggctgc agagcaaggg cagcaggacc ccaacaaaaa 1000

 cctgagcccc actgcagtca tcaacataac ttctgagaag ttagagggta 1050

 aagagcccca cccacaggat tcctcgagct gtgagatttt accctcccag 1100

 cccaggagaa ctaagagctt cctaaattac tatgcagatc tggaaacctc 1150

 agccagagaa ctagagcaga accgaggcaa tcaccatggg actgcggaag 1200

 agaaatccca gccagtccag ggccaggcct ccaccatcat tgggaatggc 1250

 gatttgctgc tgcagaaacc aaacagaccc cagtccagcc ctgaagacgg 1300

 ccaagtagcc acagtgtcat ccagcccaga aaccaagaag gatcatccga 1350

 aaacaggggc caaaaccgac tgtgcactgc accggatcca gaacctggca 1400

 ccgagcgatg aggagtccag ctggacaacg ttgtcccaag acagtgcctc 1450

 acccagctcc ccggatgaaa cagatatatg gagtgatcac tcatttcaga 1500

 ctgatccaga tttgccgcct ggctggaaaa gagtcagtga cattgccggg 1550

 acctattatt ggcacatccc aacaggaacg actcagtggg aacggcccgt 1600

 ctccatccca gcagatctcc agggttctag gaaagggtca cttagttctg 1650

 taacgccatc tcccacccca gagaacgaga aacagccatg gagtgatttt 1700

 gctgttctga atgggggaaa gattaatagt gacatttgga aggatttgca 1750

 tgcagccact gttaacccgg accccagttt aaaagagttt gaaggagcaa 1800

 ccctacgcta tgcatctttg aaactcagaa atgccccaca ccctgatgat 1850

 gatgattctt gtagtatcaa cagtgaccca gaagccaagt gttttgctgt 1900

 gcgttctctg ggatgggtag agatggcaga agaggacctc gcccccggta 1950

 aaagtagtgt tgcggtcaac aactgcatca ggcaactttc ctactgcaaa 2000

 aatgacatcc gagacacagt cgggatttgg ggagagggga aagacatgta 2050

 cctgatcctg gagaatgaca tgctcagcct ggtggacccc atggaccgca 2100

 gcgtgctgca ctcgcagccc atcgtcagca tccgcgtgtg gggcgtgggc 2150

 cgcgacaatg gccgggattt tgcttatgta gcaagagata aagatacaag 2200

 aattttgaaa tgtcatgtat ttcgatgtga cacaccagca aaagccattg 2250

 ccacaagtct ccacgagatc tgctccaaga ttatggctga acggaagaat 2300

 gccaaagcgc tggcctgcag ctccttacag gaaagggcca atgtgaacct 2350

 cgatgtccct ttgcaagtag attttccaac accaaagact gagctggtcc 2400

 agaagttcca cgtgcagtac ttgggcatgt tacctgtaga caaaccagtc 2450

 ggaatggata ttttgaacag tgccatagaa aatcttatga cctcatccaa 2500

 caaggaggac tggctgtcag tgaacatgaa cgtggctgat gccactgtga 2550

 ctgtcatcag tgaaaagaat gaagaggaag tcttagtgga atgtcgtgtg 2600

 cgattcctgt ccttcatggg tgttgggaag gacgtccaca catttgcctt 2650

 catcatggac acggggaacc agcgctttga gtgccacgtt ttctggtgcg 2700

 agcctaatgc tggtaacgtg tctgaggcgg tgcaggccgc ctgcatgtta 2750

 cgatatcaga agtgcttggt agccaggccg ccttctcaga aagttcgacc 2800

 acctccaccg ccagcagatt cagtaaccag aagagtcaca accaatgtaa 2850

 aacgaggggt cttatccctc attgacactt tgaaacagaa acgccctgtc 2900

 accgaaatgc catagctgca catgcaaaag gactcggcta tttacctgaa 2950

 gattgactag ctacactaaa gaaaatgaac tccgccatcc gaccttccat 3000

 ccagttgctg atgctttgtc ttcagagaat ttacccttaa ccaagcagtg 3050

 ttagacaagc atgttctctc gtcttgccac catcatgtga tatgaaaaga 3100

 agcatgaata attttttttg ctgtaagtta catcatgcgc agtggaaggt 3150

 ctttttctta ttgtaaatat tgtgaacatt acttaacttc acacacacac 3200

 agagaagagt gtggccccac ccctcctagt gaactaacgc tgcgtccttg 3250

 gaatgaatga tgcgtgagtt agtttcactg tcttcttggc tggacctgtc 3300

 acaagcaacc tttaagtcct acagcacttt gccctgtttt caacattgga 3350

 gtaggcactg catagcagat accattgaat tgctgtaaaa ataggatggc 3400

 gagtttgtgt tttaattttt cataaaattg aacctgttgg ttgacaaaat 3450

 tggctgttgg catcagtata gaaaccaact ggcagctttc cctgacaagc 3500

 tctttgacac atggacacca tttcatgtct acagctgttt gtgggatgtt 3550

 ggaaaaaaat gaaacttcaa aattgatgaa aaactaaatt cgaggaatta 3600

 aaatcgaaca aaacatagcc tttcttttcc gatggttttc aaactgatta 3650

 tttttaaaag agattaataa aatcataatg cattttgggt gggacatatt 3700

 tcaaacttct gccttatatt gtacggtgca gctagagaat tatagttcac 3750

 tatggccatt ctctacataa acattaagat gaaatactcc tcatcagcct 3800

 ttcatcctta gtttgagaat tagctgatat gcaatttgaa gttgaggaaa 3850

 tatcattgat atttctatca tgcacgatta ttttagattt ctaccaccgt 3900

 gtgatttttg ctagtccatg tgctagaggt aaacgttctg ctggaattct 3950

 gcatccagct ctatccccct ctgatgcttt ttgcccagaa agctgtctgt 4000

 ccatcatgta ttgtccatgg caacaaatta cattaggttg aacctttcct 4050

 tgattttatg tatttaatat tagaatttgt tggactcaac tagatatatt 4100

 ttttaattta tattttttcc attttacttt gaagatttga aatgttcata 4150

 cctgagcaaa gtctacacag gagtaatgga ctgtttaaca agtttcccaa 4200

 aacagcattt tcctgctcct tcgtatgtag gtgagaaact tagctggaaa 4250

 gacatacaaa tttagactct cgttgacatt gtcgttttaa aaggaagttg 4300

 ctaaggcgat caatctcaat attagtcttg tttacttctt cttaatgtca 4350

 aaattaacat ttacaacatc caattataaa agtaatgctt tatgtttata 4400

 cactgctatg tacttgtcaa aatggtttcc acattcttat cacatctgag 4450

 ccttaccagg tagagaaggt actaaataca ctttagaagt aaaaatatga 4500

 agtaccgaga ggctaaaccc actggcctaa gatctcacca aagttcatga 4550

 aaaccaggac taggacccac ggctcccaaa gcccgttctt gctgtgttgt 4600

 gctgcctcca tatccgtcag gaagagcctt tccagaatga ttctgggcat 4650

 atactaagaa gagcaggtat ggaaagatct attgtcaggg aatcttagaa 4700

 ttccctacac gagtgggaga aagatgtcca aattccttac gcagtggtat 4750

 tcatgatggt gccctatcta agtccaggac tgttttccta cagcgtgcct 4800

 caaaagtgtt gtagagggca ggattctaca ttcacagcct gttccatcta 4850

 cgagattttc cagatgctac ttgtggtaga cattcctaac tcatggtact 4900

 tagccaccag agatcatgat ggaatgagtg ggtggctttt ctacctgcca 4950

 ttccctcaga attcatgagg ggtgggggac agggggaccg gaattgtctt 5000

 agcaccccaa tgttatgaca aaactatgct actttagaaa cgcagtctgt 5050

 ttttcaccaa ttgacatact actgatctga agtaaccagt gccatcataa 5100

 gaaattactg cattaagaaa atccttgctg tgccctttga aaagctgttc 5150

 agaaatcatt tacagtgatc tttcatctcg gtcgctgtag tgaaacattt 5200

 tagtgtgata aatttcaaaa ttctaaacaa attacccact tttatattgg 5250

 aaatctctac cagaactccc tcttcatttt ttaaggcata catttgcttg 5300

 ttttcaagat caagaattct gagctagctt taagtagcaa actgatttat 5350

 atgtgcaatt ataggatgca ttaagatgaa tgatagcctt tacatattga 5400

 aaactttgca gacgttttgt tttgaaaatg gcattgtata gtaaatgcaa 5450

 attaattttg taaaattatg ttaaagagta tgttcagaca ctttctgcca 5500

 tggccaaaaa gtatgtatga aagtatgtgt gtatttgttt gtaaaaggat 5550

 gccaatgttt tacctgatat cttagtgaca cttcagttat ctatgcattc 5600

 tttagatctg tgattcggta aacaggcagc catgttcacg atgccttcta 5650

 tgtcttacca tatttttaat taacctgtta aatacagctt aaaatatttt 5700

 tattttattt attctatttt tactgaaata tactgcatta ttgtgttaat 5750

 gtattatctt tcctggatat tatctcccag tgtatccaga tctaagtaat 5800

 ctcagtgaac tatacattgc ctaaaaagtg gttttgtaat gatttgtagt 5850

 cacatttcta ttgggatatg tagaagaaaa ggcaaaatgc ttaaagttcc 5900

 ttttattttt taaaagcagc tagatagaca cagacttgcc acctcataca 5950

 tctgctcctt ggcaacatca aggggaacga ctagccaaca tgcctatggc 6000

 taaaaacttt cctttgcaga ctaaagcact gcttggtgct tcgtttttct 6050

 acccttcaca acatgtgtga tttcatctaa gagatatata catgtacaca 6100

 tgccctttgt ttccacctgg atacaagatc actcatagct aattaggacc 6150

 attgtttttt gttcatctgt cttgttgcat gaagggacat tagacccatt 6200

 tccattaaaa taagttcttg gtgataaact gtggcactgc tacttctttt 6250

 taaatccact ttatgatttc aagatggaca cttgtaagat gactcgacac 6300

 aaggccattg cctggaagcc ccagagcttt cctctgtttg tatggcccgt 6350

 tcatgtccca ggcattgcaa cacaaactca agatttcacc acaacatgac 6400

 aagcattttc ctaactgata ttagcacaat ttaactaata agccccttcg 6450

 ctctctagtt ggccaggctt aacctaatac acatctaacg tgtgtgccac 6500

 acggccagta gaaagtttaa cttcagcttc agggcaaaga tacccactca 6550

 caccgtgtca acgcaagcag tagttcctgg cctccagagc agcttacttc 6600

 ccctgaaaga acgctttgtt ttcctttatg cccttttcct gttgaccact 6650

 tttacacatt taaatgtaat ttgttgtgag aataaattta gctgcataaa 6700

 aaa 6703

<210> 2705
<211> 758
<212> PRT
<213> Homo sapien

<400> 2705
 Met Ser Glu Val Leu Pro Ala Asp Ser Gly Val Asp Thr Leu Ala
   1               5                  10                  15

 Val Phe Met Ala Ser Ser Gly Thr Thr Asp Val Thr Asn Arg Asn
                  20                  25                  30

 Ser Pro Ala Thr Pro Pro Asn Thr Leu Asn Leu Arg Ser Ser His
                  35                  40                  45

 Asn Glu Leu Leu Asn Ala Glu Ile Lys His Thr Glu Thr Lys Asn
                  50                  55                  60

 Ser Thr Pro Pro Lys Cys Arg Lys Lys Tyr Ala Leu Thr Asn Ile
                  65                  70                  75

 Gln Ala Ala Met Gly Leu Ser Asp Pro Ala Ala Gln Pro Leu Leu
                  80                  85                  90

 Gly Asn Gly Ser Ala Asn Ile Lys Leu Val Lys Asn Gly Glu Asn
                  95                 100                 105

 Gln Leu Arg Lys Ala Ala Glu Gln Gly Gln Gln Asp Pro Asn Lys
                 110                 115                 120

 Asn Leu Ser Pro Thr Ala Val Ile Asn Ile Thr Ser Glu Lys Leu
                 125                 130                 135

 Glu Gly Lys Glu Pro His Pro Gln Asp Ser Ser Ser Cys Glu Ile
                 140                 145                 150

 Leu Pro Ser Gln Pro Arg Arg Thr Lys Ser Phe Leu Asn Tyr Tyr
                 155                 160                 165

 Ala Asp Leu Glu Thr Ser Ala Arg Glu Leu Glu Gln Asn Arg Gly
                 170                 175                 180

 Asn His His Gly Thr Ala Glu Glu Lys Ser Gln Pro Val Gln Gly
                 185                 190                 195

 Gln Ala Ser Thr Ile Ile Gly Asn Gly Asp Leu Leu Leu Gln Lys
                 200                 205                 210

 Pro Asn Arg Pro Gln Ser Ser Pro Glu Asp Gly Gln Val Ala Thr
                 215                 220                 225

 Val Ser Ser Ser Pro Glu Thr Lys Lys Asp His Pro Lys Thr Gly
                 230                 235                 240

 Ala Lys Thr Asp Cys Ala Leu His Arg Ile Gln Asn Leu Ala Pro
                 245                 250                 255

 Ser Asp Glu Glu Ser Ser Trp Thr Thr Leu Ser Gln Asp Ser Ala
                 260                 265                 270

 Ser Pro Ser Ser Pro Asp Glu Thr Asp Ile Trp Ser Asp His Ser
                 275                 280                 285

 Phe Gln Thr Asp Pro Asp Leu Pro Pro Gly Trp Lys Arg Val Ser
                 290                 295                 300

 Asp Ile Ala Gly Thr Tyr Tyr Trp His Ile Pro Thr Gly Thr Thr
                 305                 310                 315

 Gln Trp Glu Arg Pro Val Ser Ile Pro Ala Asp Leu Gln Gly Ser
                 320                 325                 330

 Arg Lys Gly Ser Leu Ser Ser Val Thr Pro Ser Pro Thr Pro Glu
                 335                 340                 345

 Asn Glu Lys Gln Pro Trp Ser Asp Phe Ala Val Leu Asn Gly Gly
                 350                 355                 360

 Lys Ile Asn Ser Asp Ile Trp Lys Asp Leu His Ala Ala Thr Val
                 365                 370                 375

 Asn Pro Asp Pro Ser Leu Lys Glu Phe Glu Gly Ala Thr Leu Arg
                 380                 385                 390

 Tyr Ala Ser Leu Lys Leu Arg Asn Ala Pro His Pro Asp Asp Asp
                 395                 400                 405

 Asp Ser Cys Ser Ile Asn Ser Asp Pro Glu Ala Lys Cys Phe Ala
                 410                 415                 420

 Val Arg Ser Leu Gly Trp Val Glu Met Ala Glu Glu Asp Leu Ala
                 425                 430                 435

 Pro Gly Lys Ser Ser Val Ala Val Asn Asn Cys Ile Arg Gln Leu
                 440                 445                 450

 Ser Tyr Cys Lys Asn Asp Ile Arg Asp Thr Val Gly Ile Trp Gly
                 455                 460                 465

 Glu Gly Lys Asp Met Tyr Leu Ile Leu Glu Asn Asp Met Leu Ser
                 470                 475                 480

 Leu Val Asp Pro Met Asp Arg Ser Val Leu His Ser Gln Pro Ile
                 485                 490                 495

 Val Ser Ile Arg Val Trp Gly Val Gly Arg Asp Asn Gly Arg Asp
                 500                 505                 510

 Phe Ala Tyr Val Ala Arg Asp Lys Asp Thr Arg Ile Leu Lys Cys
                 515                 520                 525

 His Val Phe Arg Cys Asp Thr Pro Ala Lys Ala Ile Ala Thr Ser
                 530                 535                 540

 Leu His Glu Ile Cys Ser Lys Ile Met Ala Glu Arg Lys Asn Ala
                 545                 550                 555

 Lys Ala Leu Ala Cys Ser Ser Leu Gln Glu Arg Ala Asn Val Asn
                 560                 565                 570

 Leu Asp Val Pro Leu Gln Val Asp Phe Pro Thr Pro Lys Thr Glu
                 575                 580                 585

 Leu Val Gln Lys Phe His Val Gln Tyr Leu Gly Met Leu Pro Val
                 590                 595                 600

 Asp Lys Pro Val Gly Met Asp Ile Leu Asn Ser Ala Ile Glu Asn
                 605                 610                 615

 Leu Met Thr Ser Ser Asn Lys Glu Asp Trp Leu Ser Val Asn Met
                 620                 625                 630

 Asn Val Ala Asp Ala Thr Val Thr Val Ile Ser Glu Lys Asn Glu
                 635                 640                 645

 Glu Glu Val Leu Val Glu Cys Arg Val Arg Phe Leu Ser Phe Met
                 650                 655                 660

 Gly Val Gly Lys Asp Val His Thr Phe Ala Phe Ile Met Asp Thr
                 665                 670                 675

 Gly Asn Gln Arg Phe Glu Cys His Val Phe Trp Cys Glu Pro Asn
                 680                 685                 690

 Ala Gly Asn Val Ser Glu Ala Val Gln Ala Ala Cys Met Leu Arg
                 695                 700                 705

 Tyr Gln Lys Cys Leu Val Ala Arg Pro Pro Ser Gln Lys Val Arg
                 710                 715                 720

 Pro Pro Pro Pro Pro Ala Asp Ser Val Thr Arg Arg Val Thr Thr
                 725                 730                 735

 Asn Val Lys Arg Gly Val Leu Ser Leu Ile Asp Thr Leu Lys Gln
                 740                 745                 750

 Lys Arg Pro Val Thr Glu Met Pro
                 755

<210> 2706
<211> 3028
<212> DNA
<213> Homo sapien

<400> 2706
 caaaaatgag gtgaattaat acttgggcgc tcaggaaccc tggacagcta 50

 catgaggtgt ttaaaaactg ccctgaccat cttgccaaac aagtctctgc 100

 tcatgaggcc ccacaggatg aacgagccga ggcaggacag tgtcctgccc 150

 tgtcggaaca gtgactgctg acctgccaag agagagctgg ggactgcctg 200

 ctgtctgcca gtacaatgaa ggaagtggtt tattggtcac ccaagaaggt 250

 ggcagactgg ctgctggaga atgctatgcc agaatactgt gagcctctgg 300

 agcatttcac aggccaggac ttgatcaacc taacccaaga ggatttcaaa 350

 aaacccccct tgtgccgagt ctcctctgac aacgggcagc ggctcctgga 400

 catgatagaa accctgaaaa tggagcacca tttggaagca cacaagaacg 450

 gccatgccaa tgggcacctc aacattggcg tagacatccc cacccccgac 500

 ggcagcttca gcatcaagat taaacccaac gggatgccaa atgggtatag 550

 gaaagagatg ataaagatcc ccatgccaga actggagcgc tctcagtacc 600

 ccatggagtg gggcaagact tttctggcct ttctttatgc actttcctgt 650

 ttcgttctca ccacagtgat gatctcggtc gtccacgaac gagtacctcc 700

 taaggaggtg cagcctccac taccggacac attttttgac cattttaacc 750

 gggtgcagtg ggccttttct atttgtgaaa ttaatggcat gatccttgta 800

 ggactctggt taattcagtg gctgctctta aaatacaagt ctattattag 850

 cagaagattt ttctgcatag ttggcacgct gtacctgtat cggtgtatta 900

 caatgtatgt aactacactc ccagtacctg gtatgcattt caactgttct 950

 ccgaagcttt tcggagactg ggaagcccaa ctgcgaagaa taatgaagct 1000

 cattgctgga ggtggcttgt ctatcactgg ctctcacaac atgtgtgggg 1050

 actatctgta cagcggccac acggtcatgc taacacttac ctacttattt 1100

 atcaaagagt attcccctcg gcgactctgg tggtatcact ggatttgctg 1150

 gcttctcagc gtagttggaa tcttctgtat tctcttagcg catgaccact 1200

 acactgtgga cgtggtggtg gcatattaca tcaccacgag actcttctgg 1250

 tggtatcaca ctatggccaa tcagcaagtg ctaaaggaag cttcccagat 1300

 gaacctcctg gccagggtgt ggtggtacag gccatttcag tactttgaaa 1350

 agaatgtcca aggaattgta cctcgatctt accattggcc tttcccctgg 1400

 ccagtagtcc acctcagtag gcaagttaaa tacagccggc tggtgaatga 1450

 cacataacag ctgtacaaag tggggaaaag acaaattgtc cgaagtgcta 1500

 agaactccat gagagaagat gccataaaat aaacacctcc ctaatcctat 1550

 tatctttcaa tggttacctt gacttaacct attgagttac ctggtcagca 1600

 ctgtgatctt tttttctctc caaaggacct gcgttggaca acaataaaga 1650

 aaaatttaac ctatcatgca ctgtacacat ttcctgttca taagtttggg 1700

 atttacataa cccgcaacca ccatgttcct ttgtatatga tgcagcagca 1750

 taaatgtaag cttttatatc ataagttctg gtctttccag tcacatctgg 1800

 aaataaagcg tattattttc ttgggaaaac atacttttca tatctcttgc 1850

 cccaaagatt gggctgtaag ccattttcta gcaaatgtct ctatgaaggt 1900

 ttctaagtac ctgaatgggg tttgattctg aaatctttct acctgttgca 1950

 ccgatattca aataaaaatg atagacacag aaaggtttgg taactttggg 2000

 ttttgtaaaa tcagcaaagg cagtgtttca aaaagtgcaa aaaaaaagat 2050

 tctgttataa agtgattttc taagtatttc ctaactttat ttttcaaaat 2100

 gatgttatga acaccaaatt taaagatttt taacatgtca gagagaagag 2150

 agttaaaatt taaaaatgca tcttgggaga gaaatttgtc tatgtttcta 2200

 gtgcctttct tgtcttgatt gtatggtcag taggcaatct taaatgtttt 2250

 tatttaaaat aaagtattcc ttgaaaatat aaatatatgt atacactact 2300

 aaattttgca tttatagcta aattgaatca gaagactgct tatggtttta 2350

 aaattgcaat gacttaaata atgaggttgt taattagagt cagagcctgt 2400

 tcacatattg tgatcaggta gcaatgacat gtaccactta aattatttta 2450

 tcgtcgattt ggtagttcga ttttaactac tcaatgaaaa cagccatgaa 2500

 tatcttttct taaagagagt tttgaaaatg atcacttacc taaaacttga 2550

 aagctatgaa ttagttatcc atactctcat gacaattttg ttggtgaaca 2600

 acaaaaaaga gatctatttc tttaaaagat atttgtgcag aaactgcatg 2650

 taactctaag ttttactcct aacatacata tgtttgggga agtattctat 2700

 tctatacttg cctatgtgga gaacaaaata gttttttaag aatgaagaag 2750

 tatatatatc cattctgtat tttacgtgca gcagaattat cttccgtagg 2800

 atttttttgt gtattcacaa ggtgatattt gtattgtaaa acaataatgg 2850

 tgaaggaaat aaaaaggctt ttaaaatttt gtttgtttta aatctttgta 2900

 aagttattat tccagagagt atactggtat cttacagctt acctagatca 2950

 taaattaatc aaaatgcact ttttaataaa aactgatact taaaataaat 3000

 ggctgttatt tctaaaaaaa aaaaaaaa 3028

<210> 2707
<211> 413
<212> PRT
<213> Homo sapien

<400> 2707
 Met Lys Glu Val Val Tyr Trp Ser Pro Lys Lys Val Ala Asp Trp
   1               5                  10                  15

 Leu Leu Glu Asn Ala Met Pro Glu Tyr Cys Glu Pro Leu Glu His
                  20                  25                  30

 Phe Thr Gly Gln Asp Leu Ile Asn Leu Thr Gln Glu Asp Phe Lys
                  35                  40                  45

 Lys Pro Pro Leu Cys Arg Val Ser Ser Asp Asn Gly Gln Arg Leu
                  50                  55                  60

 Leu Asp Met Ile Glu Thr Leu Lys Met Glu His His Leu Glu Ala
                  65                  70                  75

 His Lys Asn Gly His Ala Asn Gly His Leu Asn Ile Gly Val Asp
                  80                  85                  90

 Ile Pro Thr Pro Asp Gly Ser Phe Ser Ile Lys Ile Lys Pro Asn
                  95                 100                 105

 Gly Met Pro Asn Gly Tyr Arg Lys Glu Met Ile Lys Ile Pro Met
                 110                 115                 120

 Pro Glu Leu Glu Arg Ser Gln Tyr Pro Met Glu Trp Gly Lys Thr
                 125                 130                 135

 Phe Leu Ala Phe Leu Tyr Ala Leu Ser Cys Phe Val Leu Thr Thr
                 140                 145                 150

 Val Met Ile Ser Val Val His Glu Arg Val Pro Pro Lys Glu Val
                 155                 160                 165

 Gln Pro Pro Leu Pro Asp Thr Phe Phe Asp His Phe Asn Arg Val
                 170                 175                 180

 Gln Trp Ala Phe Ser Ile Cys Glu Ile Asn Gly Met Ile Leu Val
                 185                 190                 195

 Gly Leu Trp Leu Ile Gln Trp Leu Leu Leu Lys Tyr Lys Ser Ile
                 200                 205                 210

 Ile Ser Arg Arg Phe Phe Cys Ile Val Gly Thr Leu Tyr Leu Tyr
                 215                 220                 225

 Arg Cys Ile Thr Met Tyr Val Thr Thr Leu Pro Val Pro Gly Met
                 230                 235                 240

 His Phe Asn Cys Ser Pro Lys Leu Phe Gly Asp Trp Glu Ala Gln
                 245                 250                 255

 Leu Arg Arg Ile Met Lys Leu Ile Ala Gly Gly Gly Leu Ser Ile
                 260                 265                 270

 Thr Gly Ser His Asn Met Cys Gly Asp Tyr Leu Tyr Ser Gly His
                 275                 280                 285

 Thr Val Met Leu Thr Leu Thr Tyr Leu Phe Ile Lys Glu Tyr Ser
                 290                 295                 300

 Pro Arg Arg Leu Trp Trp Tyr His Trp Ile Cys Trp Leu Leu Ser
                 305                 310                 315

 Val Val Gly Ile Phe Cys Ile Leu Leu Ala His Asp His Tyr Thr
                 320                 325                 330

 Val Asp Val Val Val Ala Tyr Tyr Ile Thr Thr Arg Leu Phe Trp
                 335                 340                 345

 Trp Tyr His Thr Met Ala Asn Gln Gln Val Leu Lys Glu Ala Ser
                 350                 355                 360

 Gln Met Asn Leu Leu Ala Arg Val Trp Trp Tyr Arg Pro Phe Gln
                 365                 370                 375

 Tyr Phe Glu Lys Asn Val Gln Gly Ile Val Pro Arg Ser Tyr His
                 380                 385                 390

 Trp Pro Phe Pro Trp Pro Val Val His Leu Ser Arg Gln Val Lys
                 395                 400                 405

 Tyr Ser Arg Leu Val Asn Asp Thr
                 410

<210> 2708
<211> 1049
<212> DNA
<213> Homo sapien

<400> 2708
 cggtcaggga tcatgaggga gagtgcgttg gagccggggc ctgtgcccga 50

 ggcgccggcg gggggtcccg tgcacgccgt gacggtggtg accctgctgg 100

 agaagctggc ctccatgctg gagactctgc gggagcggca gggaggcctg 150

 gctcgaaggc agggaggcct ggcagggtcc gtgcgccgca tccagagcgg 200

 cctgggcgct ctgagtcgca gccacgacac caccagcaac accttggcgc 250

 agctgctggc caaggcggag cgcgtgagct cgcacgccaa cgccgcccaa 300

 gagcgcgcgg tgcgccgcgc agccccaggt gcagcggctg gaggccaacc 350

 acgggctgct ggtggcgcgc gggaagctcc acgttctgct cttcaaggag 400

 gagggtgaag tcccagccag cgctttccag aaggcaccag agcccttggg 450

 cccggcggac cagtccgagc tgggcccaga gcagccggag gccgaagttg 500

 gagagagctc ggacgaggag ccggtggagt ccagggccca gcggctgcgg 550

 cgcaccggat tgcagaaggt acagagcctc cgaagggccc tttcgggccg 600

 gaaaggccct gcagcgccac cgcccacccc ggtcaagccg cctcgccttg 650

 ggcctggccg gagcgcagaa gcccagccgg aagcccagcc tgcgctggag 700

 cccacgctgg agccagagcc tccgcaggac accgaggaag atcccgggag 750

 acctggggct gccgaagaag ctctgctcca aatggagagt gtagcctgag 800

 ggctggtgtt gcctgcctcc cctgtgcttg tgccttgtcc caaaataaat 850

 cctttcagaa tgtagcactc acgccctaat aaggagcgaa tcctacatcc 900

 accaaggcgg gcgctctggc cctcccttcc ttaagcccag tcctgtgtcc 950

 tctgaaagag gtgcagtcac tcacacctgc ttgcgctcac catcaataaa 1000

 agtaatttca cccgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1049

<210> 2709
<211> 8988
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 5325-5343, 7848, 8971
<223> Unknown base

<400> 2709
 aattgcggcc gcgtcgacgc tgcgagaaga cgacagaagg gggttgcatg 50

 tactgtatgt ggagcagtgt acagtgaagc ggaggcagag cggctccgcg 100

 agcttctctc cactttccca tagagaaacc ctgactggcc gctgagggct 150

 agctacacac acgccctcac gcccggcgag cccgcgaggt cactatcata 200

 tgacaaaggc tttgccgcag ttcatcttcc tccctgtgta ctttccattt 250

 gccttcctgg aatcctgctg catcacagaa gctggaagtt ctgatgttcc 300

 actgaaatca caatggaaag tcttgacttg actggtcaca gtaatgaaag 350

 gcagtaatag aaataaggat cattcagcag aaggagaagg ggttggaaaa 400

 cgaccaaaac gaaagtgtct tcagtggcat ccattgctag caaagaaact 450

 tcttgatttt tcagaagagg aagaagagga agacgaagag gaggatattg 500

 ataaggttca acttcttggg gccgatggcc tagagcaaga tgttggtgaa 550

 actgaagatg atgaatcacc agagcagcga gcccggagac caatgaatgc 600

 atttctttta ttttgcaaac gccatcgctc tcttgtacgt caggaacacc 650

 ccaggcttga taaccgaggt gctaccaaga tactagctga ttggtgggct 700

 gttcttgatc caaaggaaaa gcagaaatac acagacatgg ccaaggagta 750

 taaggatgca tttatgaaag caaatcctgg ctacaaatgg tgtcctacca 800

 caaacaagcc tgtgaaatcc ccaacaccca ctgtcaatcc acgaaagaaa 850

 ctttgggcct tcccatctga ctcttcaaga gacttgccaa gccccaagaa 900

 agcaaagact gaagaaatgc ctcagcttaa ctttggaatg gctgatccta 950

 ctcaaatggg aggcctgagt atgctgctgt tagctggaga acatgctctt 1000

 ggcacaccag aggtatcctc tggcacatgc aggcctgatg tttcagaatc 1050

 tcctgaatta cgtcagaagt caccattgtt tcagtttgcc gagatatctt 1100

 caagtacgtc ccactctgat gcttctacaa agcagtgtca aacatctgcc 1150

 ttgtttcagt ttgcagagat ttcttcaaac acttcgcagt tgggtggtgc 1200

 tgagcctgta aaacgctgtg gaaagtctgc actctttcaa ctggcagaga 1250

 tgtgcctggc atcagaaggg atgaaaatgg aagaatcaaa gctaataaaa 1300

 gcaaaagaat ccgatggtgg aagaattaaa gaattagaga agggaaagga 1350

 agaaaaagaa attaaaatgg agaaaacaga tgaaactagg ttacagaagg 1400

 aagcagaatt tgaaaaatcg gctaaggaaa atttaagaga ttctaaggaa 1450

 ttgagaaatt ttgaggcatt gcaaatagat gacataatgg ctataaaaat 1500

 ggaagatccc aaagaaatta gaaaggaaga gttagaagaa gatcacaaat 1550

 gtagtcattt tcctgatttt tcttattctg ccagtagcaa gataataatt 1600

 agtgatgttc ccagtagaaa ggatcatatg tgccatcctc atggaattat 1650

 gatcattgag gatcccgcag cattaaacaa gccagaaaag ctaaaaaaga 1700

 aaaagaagaa aagcaaaatg gatcgacatg gaaatgataa atccacaccc 1750

 aagaagactt gcaaaaagag gcagtcttcg gaatctgaca ttgagagcgt 1800

 catatatacc attgaagccg tcgcaaaagg agactggggc atagagaaac 1850

 ttggagatac ccctcgcaag aaggtccgca catcctcaag tggcaaggga 1900

 agcattttgg atgccaagcc accaaagaaa aaagtgaaat caagagagaa 1950

 gaaaatgtca aaggagaaat cctcagacac caccaaagag tcaagacctc 2000

 cagatttcat tagtatttct gctagcaaga acatttctgg tgagacacca 2050

 gagggtataa aagcagaacc attgacccct atggaagatg cactaccacc 2100

 cagcctatca ggacaggcca agcctgagga cagtgactgt cacagaaaaa 2150

 tagaaacttg tggttccagg aaatccgaga ggtcttgcaa aggtgctctt 2200

 tataaaaccc tggtgtctga gggcatgctc acctctctgc gagctaatgt 2250

 tgacagagga aaacgaagct caggaaaagg aaactcctct gatcatgaag 2300

 ggtgttggaa tgaagaaagc tggacattta gtcagagtgg gaccagtggg 2350

 agcaagaagt tcaagaagac aaagccaaaa gaagactgtc tccttggctc 2400

 cgcaaagctg gatgaagaat ttgaaaaaaa attcaacagc ctccctcaat 2450

 atagtcctgt tacatttgac cggaaatgtg tacctgtccc aagaaaaaag 2500

 aagaagactg gaaatgtgtc ctcagaaccg actaaaacca gcaaaggaag 2550

 tggggataaa tggtcaaaca agcaactctt cttggatgcc attcacccta 2600

 cagaagccat attttcagaa gacagaaaca ccatggagcc tgttcataag 2650

 gttaaaaata tcccatccat tttcaacact ccagagccaa caacaacgca 2700

 agaacctttg gtgggcagcc aaaagagaaa agcaaggaaa accaagatta 2750

 cacaccttgt caggacagca gatggccggg tatcaccagc aggaggtact 2800

 ttggatgaca aaccaaagga acaactgcag aggagtctcc ctaaagcaac 2850

 tgagacagac tgcaatgaca aatgctcaca caacaccgag gtcggggaga 2900

 cgcggagcag tactccagaa atgcctgccg tgtctgcgtt ctttagcctc 2950

 gctgcgctgg ctgaagtggc agccatggaa aatgtgcaca gaggtcagag 3000

 gtcaactccg ctcacccatg atggacagcc aaaagaaatg ccgcaggctc 3050

 ctgtacttat ttcctgcgct gaccagtgaa gcgccctttc attgtaaaac 3100

 attgtgcttt acctactacc ctagccttgt ctttaccgag ggatgctagt 3150

 gagtccaagt ggtggaaaat atagactgca aacaagtgct tgttgcccca 3200

 cacggcccag attcacttga agcagaagtt agcatcctgg gccagtttgt 3250

 tctctcagaa cccagaatct ttgagggtaa ggttatctgt ctgatactga 3300

 gcagaaacag aatgatcctg gagctttgct ttctattgaa ggcttttgac 3350

 ggtaataggt ggtaacttgg taaaaggctg cctttactgt agctcaccca 3400

 gcatctcttt taccaaccag agagtgtgaa actagtttca tatattacct 3450

 agttattctt tcaaaacaaa acaaaaaaaa aacaaaaact gacgcactgc 3500

 actagttatt attagatatt cttagtcttt tttgtacatg gagatttaag 3550

 tttaagatgg tttatataat aggttatacc tacatttata ttgtagaata 3600

 aatattaaaa agcctgttcc agagactccc aagcagcctg ggcaggcaga 3650

 tgtaccattg ttagtggtgt atgctcggcc tcgtggtcca tatattctgc 3700

 acttttatat ttgccaccag aatggtagtt tgctggcaaa aaaaaaaaaa 3750

 agagagagag aaaaaattac aactcttaca atctgaattt ttttcttagc 3800

 cttgagtgac caagaagaat ttgcttgagg caaattgtgg caaatatttt 3850

 cccagacagg ggaagagtcc tgcagattac agattactgg tgttttcatg 3900

 ccttgaggat tcttttattt ttacataggg gtctaagtga ccaatggatt 3950

 gttcatacaa acaaaaaaaa agacaaaaat attattcaga agtgacctta 4000

 gtattacttc actattctaa acacattgaa gacactcact tcatgtggac 4050

 ttggagctac agacctttta catccatcac agattggctg gacgggttgc 4100

 aattgctatg cacagcctga ttggcactgc aggtttttag agccattttg 4150

 agtttgtgtt gtttaggagg tactgagtca atgatgaggg aggtatgcct 4200

 gaccagagtg ggactctcag tcatagatcc acctgcaagt ctctgtttcc 4250

 tttttgtgtt ttgttgcttt tgaacataaa accaaccata cataagcagc 4300

 gccaagtgga ttaactggct tagaacattc aacatattga cttaaccacc 4350

 tgacattcac agtgtcttgt ttcctagcaa cagatgcaaa gtgataaatc 4400

 aaaattagtc tgaggctaca gattttacag ggtatttgtt ctatagcaca 4450

 aagtatttcc ccactcttgc gtcacagcac aaactaccaa attttaatta 4500

 ttggattcca gcaataattt ttaatggttt tcaaactggc ggaattttga 4550

 cagtgctagt tcgagtttga agcttttgaa ttagatctct aaatggtgac 4600

 agtttacatg gttttatcta gctttcttat ttatacttga ctgaattgta 4650

 atgatttttt ttctaattgt aatttgacgt aatagccata caaaaaatga 4700

 ctctattcat actaggttta gcttctcatg gttgtagata ttacttcagt 4750

 tccggtgctg gaaaatatgt acaacatact aacaggattg aaaaaaaaat 4800

 agaggttttt cttctggttt ttttttccaa agcaggtaaa gagggtagca 4850

 aagcatcgga atgatgtgct caaaaatgca tattcctggt ggggatggag 4900

 gaagaaggca ttagtaaaag gttaatcaaa cgttacaact taaccccatt 4950

 catgcaggaa taaatcaagt gagcagttcc agacttttgc ataatatttt 5000

 tactatgatg ctgttttatt aatattttct aaatttcaaa acaaaaagtg 5050

 aatgtttgaa attgctgggt cccgatgttg gtggctgttg gagttttgga 5100

 ccactcgcta gcagtgattt gaagattata attagctaaa atccaaaaca 5150

 aaaaaccaac aacaaaaatt gtatggtgcg gaacatgcac cttgacaatg 5200

 gtactaactt gttattctat agaacacgtt agaatagatc tatttttgcc 5250

 agagcaccct ccttcagtcc tccgattaca tttcactaga gttccttacg 5300

 agattgctgt atattcctgg gaccnnnnnn nnnnnnnnnn nnnagcaaag 5350

 caaaagatta ctttttttct atgtgattaa tatcttactt gatctgcttt 5400

 tcctaaacct cagtggcttt tcccttaggc agggttgggg gtgggagggc 5450

 aacttactgg agatgactgt tttcagatac tttaaaacaa acctttttgt 5500

 agaaatgctt aatttttaag cggttaggca ctgagagtag cagaaatcct 5550

 gcaaagcttt atagttcctt agactcacct tgtcgattct ctgagtaaag 5600

 tcttgatttc aataattgtg cttctcatgc cctgaatctg ctggagagga 5650

 gtgttgttat tttcaggtaa caacattcgt tagcacaaat atttcagacc 5700

 aatattagtg ctctccaccc caccttttgt tatcattttc atttcatttc 5750

 tctcattctt ttttattttg gaaaatcata ttgctatagt gtgtacttta 5800

 atctgccagc agataccatc tacactaaca tttgtcccac agcatcctca 5850

 agagaaaaag ttgttgcacc ttatatatat ctcaagcaaa ccaaaatatg 5900

 atgctcttct gctttgtttt attctaaatt gttgtatcat atctttctga 5950

 aaccattctg aatttagttg aaattatcaa tatttatgct tttaacctta 6000

 atttctggat tcaagcctgt atataaatct tttgaaaaaa aattgtccta 6050

 gcccttctct gcgatgctgg aagtagaaga ttgcgtctca gatggagacg 6100

 cagtactgtt ccagttttct ttagcctttt atttatttag ttattctggg 6150

 tatttcctat gtaattttga agtgtgtaga gtatattata gtaactgaag 6200

 ctgcagctgt aagaagctga gtgaaagaaa aaatactgta agacatcctt 6250

 aaagttttta tttgtttggg tactgtatat gagatcagga aaaagaaaaa 6300

 tgtcccacag ccacattgga aatacaggtt cttgtcccca aattaggtta 6350

 gttcccagat tttagatcaa aactgttaat tcattaaaac cccttttaaa 6400

 aggtaaattc tactgttgta attccgatag tctttttccc acaaatatca 6450

 gaaatatatt tatttaattc tgtcagatga gctttctacc gatgccatgt 6500

 cccaaagcca tgttaaaata attcccacgt tatcattgtg attctacttc 6550

 ctgccactaa aattgctgga gaaacaaaat aatgatggaa cactatgaac 6600

 aaaaaggagc atctgaactg gtctggttat ttagaatcca atgtgttcaa 6650

 atccttttgt tttcttatta agtcagatgc tactgtaagt cagataaaat 6700

 tttgtttgca ctctgcagtc tttggctcaa tgtatggaaa tgtttgcacc 6750

 tatgtaaagt cacaagctaa ttacaaattg ctacagaaca ggagtaagct 6800

 gaaaactgaa tgccatgttt tgtttataag gtggggaggg gagggaaaat 6850

 accaaaaaac tctgttccaa gtttggcatt tgacattaat gtgaagcagt 6900

 gggaccatgc tgcctgctaa actactgtat gaatcgtaaa tgttctgaag 6950

 acgagcagct ggaggctgga ggatggcatt ccatacagca aaggagaagc 7000

 acccaccact tcatctggga aaaggaagga aattgcagga ggcctggagc 7050

 catcatttgt aaaggggatg ttgcggggtg tgatgctgtt gaggagattc 7100

 accttcaatt gcactgctcc acagagccct catataaggc caatcctaat 7150

 gggctacctc ggctttaaaa gttaatttca gtaagtcctg tttcaaaagt 7200

 ttgtcttttt ttgcttctac cttcagtgcc actattttcc actgcagtgt 7250

 tttgacttca caaactgcct cctccagaga gaacaatgta ttgctgaaaa 7300

 tgggcagtag aagcaaatgc tgttgttaca tttgacctat aaagtattca 7350

 gagtgactgc taggtagaaa ttaaaactta gctttcccaa atagctcctt 7400

 attttgcacc ttataaaaag tatactaatt gttaattaga tgttgctttt 7450

 gtttatacaa gcattcccaa agaactagat ttggattttg ttttgagttt 7500

 ttggattttt aaaaattatc ttatttagat tgactaacag catacttaca 7550

 attttaaaag aagctgttgt tcagttcatc ttaccagatg tgtctggcga 7600

 agtattcagg gtttgatgga ctgctttact ttcgtttgga agtgatagct 7650

 aagtttatta tactctatat taaacaactt tgttcatttc actgaggacc 7700

 ttatcttcct tatatttcag aacaaagaag caacaagcgt gaataaaaag 7750

 acaaatgtat ttgactccct cataatcccc atctgtatgt gctacccttc 7800

 cttcaaatat ataaatgtgc atcttttttt ttaaaaaaaa aaaaaaanaa 7850

 ggttcctctt ctggccaaat ttgatctatg gtggtatgat tcatactgtt 7900

 aaattgagag aggaaacctt gtggttaaaa attatatggc tgctgttttc 7950

 tttttgcagt cagtggtcaa aactgatcat gtgcttaaat cgatttttat 8000

 gcacagaact agttattgtg aacattactg ctccctccaa agatttcctg 8050

 ataacttggg ccagaggtgg ttactgagta acaaggatct aattcaatgc 8100

 ctcaaaactc ttccacccac aatgcaaatc ttacctcaca agctctaacc 8150

 taaatcacag agacatgcat gtttcatgca ttaacactga tttcgctctg 8200

 tggcccacca gaggggtggg ctcatgtccc ctgactcctc acatgagtgc 8250

 ctcagctcta agagccgtgg aacggggggt agggaaggtt tgcgatctgg 8300

 agctcagcaa ctggctcagc aacgttttct ccatttcatt agcactaaac 8350

 aagtctcttg ctctcaggaa tttgtcagaa aaaagaataa aatcacctga 8400

 gactccacat accagattat aaactcttct cgtaggtttg aattgcttac 8450

 tcacatgtca taaattaacc acagcttcat ttgaccacca ggtctaaagt 8500

 ctgttgacag tttcagcatg actgaatcgc tcattttttt tttttgcttt 8550

 cagaaattgg cttggttctc tttagagttg gtgtaaacat gccatgtaat 8600

 aaatgatttc cacttaatgg tacaacagaa ttattgcttt cttagatgta 8650

 tgtgtagtaa aagtcaatat acacatttat ataatttctt tcttcaaaat 8700

 cttataccta atttgatatt tctaaaaatt gcacatgtaa gtcatgtgta 8750

 taacatgcta aagtacttta actgtgatct taaaactgaa taaaaatatt 8800

 taataaaact ttgaaatatt ttaaagatat tattcaaata tatttcttta 8850

 tgttcacact actggccgta gagtatgtgc ctttaatgta ccattttcac 8900

 taaaaacagt aggaaaaata ctaataaaag taagatattt caactatttt 8950

 agaacatcga atgatgtgtc nccctaaact gtgtttgc 8988

<210> 2710
<211> 911
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 5325-5343, 7848, 8971
<223> Unknown amino acid

<400> 2710
 Met Lys Gly Ser Asn Arg Asn Lys Asp His Ser Ala Glu Gly Glu
   1               5                  10                  15

 Gly Val Gly Lys Arg Pro Lys Arg Lys Cys Leu Gln Trp His Pro
                  20                  25                  30

 Leu Leu Ala Lys Lys Leu Leu Asp Phe Ser Glu Glu Glu Glu Glu
                  35                  40                  45

 Glu Asp Glu Glu Glu Asp Ile Asp Lys Val Gln Leu Leu Gly Ala
                  50                  55                  60

 Asp Gly Leu Glu Gln Asp Val Gly Glu Thr Glu Asp Asp Glu Ser
                  65                  70                  75

 Pro Glu Gln Arg Ala Arg Arg Pro Met Asn Ala Phe Leu Leu Phe
                  80                  85                  90

 Cys Lys Arg His Arg Ser Leu Val Arg Gln Glu His Pro Arg Leu
                  95                 100                 105

 Asp Asn Arg Gly Ala Thr Lys Ile Leu Ala Asp Trp Trp Ala Val
                 110                 115                 120

 Leu Asp Pro Lys Glu Lys Gln Lys Tyr Thr Asp Met Ala Lys Glu
                 125                 130                 135

 Tyr Lys Asp Ala Phe Met Lys Ala Asn Pro Gly Tyr Lys Trp Cys
                 140                 145                 150

 Pro Thr Thr Asn Lys Pro Val Lys Ser Pro Thr Pro Thr Val Asn
                 155                 160                 165

 Pro Arg Lys Lys Leu Trp Ala Phe Pro Ser Asp Ser Ser Arg Asp
                 170                 175                 180

 Leu Pro Ser Pro Lys Lys Ala Lys Thr Glu Glu Met Pro Gln Leu
                 185                 190                 195

 Asn Phe Gly Met Ala Asp Pro Thr Gln Met Gly Gly Leu Ser Met
                 200                 205                 210

 Leu Leu Leu Ala Gly Glu His Ala Leu Gly Thr Pro Glu Val Ser
                 215                 220                 225

 Ser Gly Thr Cys Arg Pro Asp Val Ser Glu Ser Pro Glu Leu Arg
                 230                 235                 240

 Gln Lys Ser Pro Leu Phe Gln Phe Ala Glu Ile Ser Ser Ser Thr
                 245                 250                 255

 Ser His Ser Asp Ala Ser Thr Lys Gln Cys Gln Thr Ser Ala Leu
                 260                 265                 270

 Phe Gln Phe Ala Glu Ile Ser Ser Asn Thr Ser Gln Leu Gly Gly
                 275                 280                 285

 Ala Glu Pro Val Lys Arg Cys Gly Lys Ser Ala Leu Phe Gln Leu
                 290                 295                 300

 Ala Glu Met Cys Leu Ala Ser Glu Gly Met Lys Met Glu Glu Ser
                 305                 310                 315

 Lys Leu Ile Lys Ala Lys Glu Ser Asp Gly Gly Arg Ile Lys Glu
                 320                 325                 330

 Leu Glu Lys Gly Lys Glu Glu Lys Glu Ile Lys Met Glu Lys Thr
                 335                 340                 345

 Asp Glu Thr Arg Leu Gln Lys Glu Ala Glu Phe Glu Lys Ser Ala
                 350                 355                 360

 Lys Glu Asn Leu Arg Asp Ser Lys Glu Leu Arg Asn Phe Glu Ala
                 365                 370                 375

 Leu Gln Ile Asp Asp Ile Met Ala Ile Lys Met Glu Asp Pro Lys
                 380                 385                 390

 Glu Ile Arg Lys Glu Glu Leu Glu Glu Asp His Lys Cys Ser His
                 395                 400                 405

 Phe Pro Asp Phe Ser Tyr Ser Ala Ser Ser Lys Ile Ile Ile Ser
                 410                 415                 420

 Asp Val Pro Ser Arg Lys Asp His Met Cys His Pro His Gly Ile
                 425                 430                 435

 Met Ile Ile Glu Asp Pro Ala Ala Leu Asn Lys Pro Glu Lys Leu
                 440                 445                 450

 Lys Lys Lys Lys Lys Lys Ser Lys Met Asp Arg His Gly Asn Asp
                 455                 460                 465

 Lys Ser Thr Pro Lys Lys Thr Cys Lys Lys Arg Gln Ser Ser Glu
                 470                 475                 480

 Ser Asp Ile Glu Ser Val Ile Tyr Thr Ile Glu Ala Val Ala Lys
                 485                 490                 495

 Gly Asp Trp Gly Ile Glu Lys Leu Gly Asp Thr Pro Arg Lys Lys
                 500                 505                 510

 Val Arg Thr Ser Ser Ser Gly Lys Gly Ser Ile Leu Asp Ala Lys
                 515                 520                 525

 Pro Pro Lys Lys Lys Val Lys Ser Arg Glu Lys Lys Met Ser Lys
                 530                 535                 540

 Glu Lys Ser Ser Asp Thr Thr Lys Glu Ser Arg Pro Pro Asp Phe
                 545                 550                 555

 Ile Ser Ile Ser Ala Ser Lys Asn Ile Ser Gly Glu Thr Pro Glu
                 560                 565                 570

 Gly Ile Lys Ala Glu Pro Leu Thr Pro Met Glu Asp Ala Leu Pro
                 575                 580                 585

 Pro Ser Leu Ser Gly Gln Ala Lys Pro Glu Asp Ser Asp Cys His
                 590                 595                 600

 Arg Lys Ile Glu Thr Cys Gly Ser Arg Lys Ser Glu Arg Ser Cys
                 605                 610                 615

 Lys Gly Ala Leu Tyr Lys Thr Leu Val Ser Glu Gly Met Leu Thr
                 620                 625                 630

 Ser Leu Arg Ala Asn Val Asp Arg Gly Lys Arg Ser Ser Gly Lys
                 635                 640                 645

 Gly Asn Ser Ser Asp His Glu Gly Cys Trp Asn Glu Glu Ser Trp
                 650                 655                 660

 Thr Phe Ser Gln Ser Gly Thr Ser Gly Ser Lys Lys Phe Lys Lys
                 665                 670                 675

 Thr Lys Pro Lys Glu Asp Cys Leu Leu Gly Ser Ala Lys Leu Asp
                 680                 685                 690

 Glu Glu Phe Glu Lys Lys Phe Asn Ser Leu Pro Gln Tyr Ser Pro
                 695                 700                 705

 Val Thr Phe Asp Arg Lys Cys Val Pro Val Pro Arg Lys Lys Lys
                 710                 715                 720

 Lys Thr Gly Asn Val Ser Ser Glu Pro Thr Lys Thr Ser Lys Gly
                 725                 730                 735

 Ser Gly Asp Lys Trp Ser Asn Lys Gln Leu Phe Leu Asp Ala Ile
                 740                 745                 750

 His Pro Thr Glu Ala Ile Phe Ser Glu Asp Arg Asn Thr Met Glu
                 755                 760                 765

 Pro Val His Lys Val Lys Asn Ile Pro Ser Ile Phe Asn Thr Pro
                 770                 775                 780

 Glu Pro Thr Thr Thr Gln Glu Pro Leu Val Gly Ser Gln Lys Arg
                 785                 790                 795

 Lys Ala Arg Lys Thr Lys Ile Thr His Leu Val Arg Thr Ala Asp
                 800                 805                 810

 Gly Arg Val Ser Pro Ala Gly Gly Thr Leu Asp Asp Lys Pro Lys
                 815                 820                 825

 Glu Gln Leu Gln Arg Ser Leu Pro Lys Ala Thr Glu Thr Asp Cys
                 830                 835                 840

 Asn Asp Lys Cys Ser His Asn Thr Glu Val Gly Glu Thr Arg Ser
                 845                 850                 855

 Ser Thr Pro Glu Met Pro Ala Val Ser Ala Phe Phe Ser Leu Ala
                 860                 865                 870

 Ala Leu Ala Glu Val Ala Ala Met Glu Asn Val His Arg Gly Gln
                 875                 880                 885

 Arg Ser Thr Pro Leu Thr His Asp Gly Gln Pro Lys Glu Met Pro
                 890                 895                 900

 Gln Ala Pro Val Leu Ile Ser Cys Ala Asp Gln
                 905                 910

<210> 2711
<211> 4408
<212> DNA
<213> Homo sapien

<400> 2711
 gggcgcggag gcgaccgcca tggcgttcct caaactccgt gaccagccat 50

 cactggtgca agctatattt aacggagatc ctgatgaagt tcgagcacta 100

 atatttaaga aagaagatgt taactttcag gacaatgaaa agcgaacccc 150

 attgcacgcc gcagcttacc ttggagatgc agaaatcatt gaacttctta 200

 ttttatctgg agctagagtt aatgccaaag acagcaaatg gttgacacct 250

 ttacacagag cagttgcatc ttgtagtgag gaagcagttc aggtactttt 300

 gaagcattct gcagatgtta atgctcgaga caaaaattgg caaacccctt 350

 tacatatagc tgctgctaat aaagctgtaa agtgtgctga agctttggta 400

 cctcttctga gtaatgtaaa cgtatctgat cgagcaggga ggactgcatt 450

 acatcatgca gctttcagtg gacatggtga gatggtcaaa ctactcttgt 500

 ctagaggtgc caatattaat gcttttgaca agaaagatag gcgtgctatc 550

 cattgggcag catatatggg tcacattgaa gtagtgaaat tgcttgtgtc 600

 gcatggagct gaagtgacat gcaaggataa aaagtcttat acacctcttc 650

 atgcagcagc ctctagtgga atgatcagcg tagtcaagta ccttctagat 700

 cttggagttg atatgaatga accaaatgcc tatggaaata cacctcttca 750

 tgtagcctgc tataatggac aagatgttgt agtgaatgaa cttatagact 800

 gtggtgctat tgtgaatcaa aagaatgaaa aaggatttac tcctttgcac 850

 tttgctgctg catcaacaca tggagcattg tgtttagagc ttctagttgg 900

 caatggggcc gatgtcaata tgaagagtaa agatgggaaa accccactac 950

 acatgactgc tctccacggt agattctccc gatcacaaac cattatccag 1000

 agtggagctg taatcgactg tgaggataag aatggaaata cccctttgca 1050

 catagcagca cggtatggcc atgagctgct gatcaacact cttattacaa 1100

 gtggtgctga cactgcaaag cgtggcatac atggaatgtt ccccctccat 1150

 ttggcagcct taagcggctt ttcagattgc tgcagaaaac ttctttcttc 1200

 aggatttgat atagataccc cagatgattt tggcaggact tgtctacatg 1250

 cagctgcagc tggagggaat ttggagtgcc taaaccttct gctgaatact 1300

 ggtgcagact ttaataaaaa ggacaaattt gggagatctc cactgcacta 1350

 cgctgctgcc aactgcaatt accagtgcct gtttgctctt gtgggatcag 1400

 gagcaagtgt gaatgacctt gatgaaagag gctgcacacc cctgcactat 1450

 gcagctacat cagacacaga tggcaagtgc ctggaatact tattaagaaa 1500

 cgatgcaaat ccagggatcc gtgataagca aggatacaac gcagttcatt 1550

 attcagctgc ttatggtcac cgtctatgtc ttcagctgat tgcaagtgaa 1600

 actcctctag atgttttaat ggaaacctca ggaacagaca tgctgagtga 1650

 ttcagataat agagcaacaa taagcccttt acacttggct gcctatcatg 1700

 gtcaccatca agcactggaa gtgttggtac agtctttgtt agatcttgat 1750

 gtcagaaata gtagtggaag aacaccccta gatcttgcag cttttaaggg 1800

 ccatgttgaa tgtgtggatg tactcattaa tcagggagcc tcaatcttag 1850

 taaaagatta cattttgaag aggacaccta ttcatgcagc agcaacaaat 1900

 ggtcattcag aatgcttacg gctattaata ggaaatgcag aaccacagaa 1950

 tgcagtggat attcaagatg gaaatggaca gacgcctctg atgctatctg 2000

 ttctcaacgg gcacacagac tgtgtttact cattgctgaa caaaggagca 2050

 aatgtagatg ccaaagataa gtggggaagg acagcgttgc atagaggggc 2100

 agttacaggc catgaagaat gtgtagatgc attacttcaa catggtgcta 2150

 agtgcttact tcgggatagc aggggccgga cgcctataca cctgtctgct 2200

 gcctgtggac acattggtgt tcttggagcc cttttgcagt cagcagcatc 2250

 tatggatgca aatccagcca cagcagacaa tcatggatat acggcacttc 2300

 actgggcttg ctacaatggt cacgagacat gtgtagaact gcttttagaa 2350

 caggaagttt tccagaaaac ggaaggaaat gcttttagtc cattgcattg 2400

 tgccgtgata aatgacaacg aaggtgctgc tgagatgtta attgatacat 2450

 taggtgccag cattgtgaac gccacagatt caaaaggaag aactcctctc 2500

 catgcagccg ccttcacaga ccatgtagag tgtttacagc tgctgctcag 2550

 ccataatgct caagtcaatt ctgtggactc tacagggaaa acacctctta 2600

 tgatggctgc agaaaatgga caaacaaata cagttgagat gctggttagc 2650

 agtgctagtg cagaactgac tttacaagat aacagtaaaa atactgccct 2700

 ccatttggct tgtagcaagg gtcatgaaac tagtgccttg ttaatactgg 2750

 aaaagataac agatagaaac ctcatcaatg caaccaacgc agccttgcaa 2800

 acacctctgc atgttgctgc ccgaaatggg ctaacaatgg tggttcagga 2850

 acttttggga aaaggagcaa gtgtgcttgc agtagatgaa aatggctata 2900

 ccccagcttt ggcctgtgct cccaataagg atgtggctga ttgcctggct 2950

 ctcattttgg ccaccatgat gcctgtctca tcaagtagtc ctttatcatc 3000

 cttaacattc aatgccatta accgttatac caacacctca aaaacagtca 3050

 gctttgaagc tttgcccatc atgaggaatg aacctagctc ctattgcagt 3100

 ttcaataaca ttggagggga acaggagtac ttatacactg acgtggatga 3150

 gctcaacgac tccgattctg agacctactg agaggctgag gaggagggag 3200

 ttctcacagt aaagcttcaa actgtgcttt ttcaggaaaa aggcactttg 3250

 atattcacgt agaaattcaa cctaagagga aagatcccac agtgagccaa 3300

 tgttaagaga tctgatggca ttaggaggaa gagttttaaa ggaattctct 3350

 tctgaattcc ctgagggaat tttctagaat ctcagaattg aaagagacct 3400

 gaggttcatc cagtctctaa cctcttaaca aatgcaggag tcccttctac 3450

 aagggtgatc tttccacctt gaacacttcc aagtgactct acctcaccaa 3500

 gcagtccatt cagttgttga gcagctctaa ctgttagaaa ggtcttcctt 3550

 agatggagtt gaagcctccc tcccggtaac ttctgtcttt gggcctgggt 3600

 ctgtcctcca agagaaccct gagaatgttg gaaggatgaa tctcgcacat 3650

 tctgccatgt cttctctttt acaggctgtt tgacttctct gctgaagtga 3700

 tttccagaag gactcatttg acacactatt agatttacca catctaatga 3750

 aatccaaggt gtagctataa agtgacaagc tgtttttaat ttatcacata 3800

 caccagaact tctatcctgc atcacttata tgtaaatgat gctgttacca 3850

 aaaacattaa ggtagttctt gcgaatgcca ccccactaag aaaactattt 3900

 cattactttt gtaatccatc tgtgagagtc tgccccccag cttaaccact 3950

 tcctttgatc tgcacccaat gaagggaaac cccaaagtac tgtctcaaat 4000

 ggtatttgaa ctacgccagt attgttggaa taagtacatt aattacttga 4050

 atgaatgaac acagcaccgt agaaatttcc tttatggtta caccttgtat 4100

 gtctaaagca ttcaggccct gttctgtagt gtttcttatc ctcacacaga 4150

 gtagaaaagc ctgtttgctt tatttaactt atacataaaa gatgacatct 4200

 gaaatatctg atgtgtatta taataccagc ttctgctcta gaactacttt 4250

 gggtgaaatg gtggtaatag caaatgacct cctttaacaa gacactcatc 4300

 tcaaacaatg ccatttagtt caggagatct ctaagtgtag ctgtaaattt 4350

 tggggttaat ttggcttata ttggaccttt taaaagaaat aaagtttttt 4400

 aatgcaat 4408

<210> 2712
<211> 1059
<212> PRT
<213> Homo sapien

<400> 2712
 Gly Ala Glu Ala Thr Ala Met Ala Phe Leu Lys Leu Arg Asp Gln
   1               5                  10                  15

 Pro Ser Leu Val Gln Ala Ile Phe Asn Gly Asp Pro Asp Glu Val
                  20                  25                  30

 Arg Ala Leu Ile Phe Lys Lys Glu Asp Val Asn Phe Gln Asp Asn
                  35                  40                  45

 Glu Lys Arg Thr Pro Leu His Ala Ala Ala Tyr Leu Gly Asp Ala
                  50                  55                  60

 Glu Ile Ile Glu Leu Leu Ile Leu Ser Gly Ala Arg Val Asn Ala
                  65                  70                  75

 Lys Asp Ser Lys Trp Leu Thr Pro Leu His Arg Ala Val Ala Ser
                  80                  85                  90

 Cys Ser Glu Glu Ala Val Gln Val Leu Leu Lys His Ser Ala Asp
                  95                 100                 105

 Val Asn Ala Arg Asp Lys Asn Trp Gln Thr Pro Leu His Ile Ala
                 110                 115                 120

 Ala Ala Asn Lys Ala Val Lys Cys Ala Glu Ala Leu Val Pro Leu
                 125                 130                 135

 Leu Ser Asn Val Asn Val Ser Asp Arg Ala Gly Arg Thr Ala Leu
                 140                 145                 150

 His His Ala Ala Phe Ser Gly His Gly Glu Met Val Lys Leu Leu
                 155                 160                 165

 Leu Ser Arg Gly Ala Asn Ile Asn Ala Phe Asp Lys Lys Asp Arg
                 170                 175                 180

 Arg Ala Ile His Trp Ala Ala Tyr Met Gly His Ile Glu Val Val
                 185                 190                 195

 Lys Leu Leu Val Ser His Gly Ala Glu Val Thr Cys Lys Asp Lys
                 200                 205                 210

 Lys Ser Tyr Thr Pro Leu His Ala Ala Ala Ser Ser Gly Met Ile
                 215                 220                 225

 Ser Val Val Lys Tyr Leu Leu Asp Leu Gly Val Asp Met Asn Glu
                 230                 235                 240

 Pro Asn Ala Tyr Gly Asn Thr Pro Leu His Val Ala Cys Tyr Asn
                 245                 250                 255

 Gly Gln Asp Val Val Val Asn Glu Leu Ile Asp Cys Gly Ala Ile
                 260                 265                 270

 Val Asn Gln Lys Asn Glu Lys Gly Phe Thr Pro Leu His Phe Ala
                 275                 280                 285

 Ala Ala Ser Thr His Gly Ala Leu Cys Leu Glu Leu Leu Val Gly
                 290                 295                 300

 Asn Gly Ala Asp Val Asn Met Lys Ser Lys Asp Gly Lys Thr Pro
                 305                 310                 315

 Leu His Met Thr Ala Leu His Gly Arg Phe Ser Arg Ser Gln Thr
                 320                 325                 330

 Ile Ile Gln Ser Gly Ala Val Ile Asp Cys Glu Asp Lys Asn Gly
                 335                 340                 345

 Asn Thr Pro Leu His Ile Ala Ala Arg Tyr Gly His Glu Leu Leu
                 350                 355                 360

 Ile Asn Thr Leu Ile Thr Ser Gly Ala Asp Thr Ala Lys Arg Gly
                 365                 370                 375

 Ile His Gly Met Phe Pro Leu His Leu Ala Ala Leu Ser Gly Phe
                 380                 385                 390

 Ser Asp Cys Cys Arg Lys Leu Leu Ser Ser Gly Phe Asp Ile Asp
                 395                 400                 405

 Thr Pro Asp Asp Phe Gly Arg Thr Cys Leu His Ala Ala Ala Ala
                 410                 415                 420

 Gly Gly Asn Leu Glu Cys Leu Asn Leu Leu Leu Asn Thr Gly Ala
                 425                 430                 435

 Asp Phe Asn Lys Lys Asp Lys Phe Gly Arg Ser Pro Leu His Tyr
                 440                 445                 450

 Ala Ala Ala Asn Cys Asn Tyr Gln Cys Leu Phe Ala Leu Val Gly
                 455                 460                 465

 Ser Gly Ala Ser Val Asn Asp Leu Asp Glu Arg Gly Cys Thr Pro
                 470                 475                 480

 Leu His Tyr Ala Ala Thr Ser Asp Thr Asp Gly Lys Cys Leu Glu
                 485                 490                 495

 Tyr Leu Leu Arg Asn Asp Ala Asn Pro Gly Ile Arg Asp Lys Gln
                 500                 505                 510

 Gly Tyr Asn Ala Val His Tyr Ser Ala Ala Tyr Gly His Arg Leu
                 515                 520                 525

 Cys Leu Gln Leu Ile Ala Ser Glu Thr Pro Leu Asp Val Leu Met
                 530                 535                 540

 Glu Thr Ser Gly Thr Asp Met Leu Ser Asp Ser Asp Asn Arg Ala
                 545                 550                 555

 Thr Ile Ser Pro Leu His Leu Ala Ala Tyr His Gly His His Gln
                 560                 565                 570

 Ala Leu Glu Val Leu Val Gln Ser Leu Leu Asp Leu Asp Val Arg
                 575                 580                 585

 Asn Ser Ser Gly Arg Thr Pro Leu Asp Leu Ala Ala Phe Lys Gly
                 590                 595                 600

 His Val Glu Cys Val Asp Val Leu Ile Asn Gln Gly Ala Ser Ile
                 605                 610                 615

 Leu Val Lys Asp Tyr Ile Leu Lys Arg Thr Pro Ile His Ala Ala
                 620                 625                 630

 Ala Thr Asn Gly His Ser Glu Cys Leu Arg Leu Leu Ile Gly Asn
                 635                 640                 645

 Ala Glu Pro Gln Asn Ala Val Asp Ile Gln Asp Gly Asn Gly Gln
                 650                 655                 660

 Thr Pro Leu Met Leu Ser Val Leu Asn Gly His Thr Asp Cys Val
                 665                 670                 675

 Tyr Ser Leu Leu Asn Lys Gly Ala Asn Val Asp Ala Lys Asp Lys
                 680                 685                 690

 Trp Gly Arg Thr Ala Leu His Arg Gly Ala Val Thr Gly His Glu
                 695                 700                 705

 Glu Cys Val Asp Ala Leu Leu Gln His Gly Ala Lys Cys Leu Leu
                 710                 715                 720

 Arg Asp Ser Arg Gly Arg Thr Pro Ile His Leu Ser Ala Ala Cys
                 725                 730                 735

 Gly His Ile Gly Val Leu Gly Ala Leu Leu Gln Ser Ala Ala Ser
                 740                 745                 750

 Met Asp Ala Asn Pro Ala Thr Ala Asp Asn His Gly Tyr Thr Ala
                 755                 760                 765

 Leu His Trp Ala Cys Tyr Asn Gly His Glu Thr Cys Val Glu Leu
                 770                 775                 780

 Leu Leu Glu Gln Glu Val Phe Gln Lys Thr Glu Gly Asn Ala Phe
                 785                 790                 795

 Ser Pro Leu His Cys Ala Val Ile Asn Asp Asn Glu Gly Ala Ala
                 800                 805                 810

 Glu Met Leu Ile Asp Thr Leu Gly Ala Ser Ile Val Asn Ala Thr
                 815                 820                 825

 Asp Ser Lys Gly Arg Thr Pro Leu His Ala Ala Ala Phe Thr Asp
                 830                 835                 840

 His Val Glu Cys Leu Gln Leu Leu Leu Ser His Asn Ala Gln Val
                 845                 850                 855

 Asn Ser Val Asp Ser Thr Gly Lys Thr Pro Leu Met Met Ala Ala
                 860                 865                 870

 Glu Asn Gly Gln Thr Asn Thr Val Glu Met Leu Val Ser Ser Ala
                 875                 880                 885

 Ser Ala Glu Leu Thr Leu Gln Asp Asn Ser Lys Asn Thr Ala Leu
                 890                 895                 900

 His Leu Ala Cys Ser Lys Gly His Glu Thr Ser Ala Leu Leu Ile
                 905                 910                 915

 Leu Glu Lys Ile Thr Asp Arg Asn Leu Ile Asn Ala Thr Asn Ala
                 920                 925                 930

 Ala Leu Gln Thr Pro Leu His Val Ala Ala Arg Asn Gly Leu Thr
                 935                 940                 945

 Met Val Val Gln Glu Leu Leu Gly Lys Gly Ala Ser Val Leu Ala
                 950                 955                 960

 Val Asp Glu Asn Gly Tyr Thr Pro Ala Leu Ala Cys Ala Pro Asn
                 965                 970                 975

 Lys Asp Val Ala Asp Cys Leu Ala Leu Ile Leu Ala Thr Met Met
                 980                 985                 990

 Pro Val Ser Ser Ser Ser Pro Leu Ser Ser Leu Thr Phe Asn Ala
                 995                1000                1005

 Ile Asn Arg Tyr Thr Asn Thr Ser Lys Thr Val Ser Phe Glu Ala
                1010                1015                1020

 Leu Pro Ile Met Arg Asn Glu Pro Ser Ser Tyr Cys Ser Phe Asn
                1025                1030                1035

 Asn Ile Gly Gly Glu Gln Glu Tyr Leu Tyr Thr Asp Val Asp Glu
                1040                1045                1050

 Leu Asn Asp Ser Asp Ser Glu Thr Tyr
                1055

<210> 2713
<211> 4857
<212> DNA
<213> Homo sapien

<400> 2713
 ccgccgccac tgccgtcggg taaggtccca gcacggacat ggcctcgcgc 50

 ggcgcccgcc cgggcccgag tcccccgcgc cccgctttgt agccccccgg 100

 cggagaggcg gcctcgacgg tgcggacggc gcagacggcc gggcgggcgg 150

 catggaggcg gcgcatctgc tcccggccgc cgacgtgctg cgccacttct 200

 cggtgacagc cgagggcggc ctgagcccgg cgcaggtgac cggcgcgcgg 250

 gagcgctacg gccccaacga gctcccgagt gaggaaggga agtccctgtg 300

 ggagctggtg ctggaacagt ttgaggacct cctggtgcgc atcctgctgc 350

 tggctgccct tgtctccttt gtcctggcct ggttcgagga gggcgaggag 400

 accacgaccg ccttcgtgga gcccctggtc atcatgctga tcctcgtggc 450

 caacgccatt gtgggcgtgt ggcaggaacg caacgccgag agtgccatcg 500

 aggccctgaa ggagtatgag cctgagatgg gcaaggtgat ccgctcggac 550

 cgcaagggcg tgcagaggat ccgtgcccgg gacatcgtcc caggggacat 600

 tgtagaagtg gcagtggggg acaaagtgcc tgctgacctc cgcctcatcg 650

 agatcaagtc caccacgctg cgagtggacc agtccatcct gacgggtgaa 700

 tctgtgtccg tgaccaagca cacagaggcc atcccagacc ccagagctgt 750

 gaaccaggac aagaagaaca tgctgttttc tggcaccaat atcacatcgg 800

 gcaaagcggt gggtgtggcc gtggccaccg gcctgcacac ggagctgggc 850

 aagatccgga gccagatggc ggcagtcgag cccgagcgga cgccgctgca 900

 gcgcaagctg gacgagtttg gacggcagct gtcccacgcc atctctgtga 950

 tctgcgtggc cgtgtgggtc atcaacatcg gccacttcgc cgacccggcc 1000

 cacggtggct cctggctgcg tggcgctgtc tactacttca agatcgccgt 1050

 ggccctggcg gtggcggcca tccccgaggg cctcccggct gtcatcacta 1100

 catgcctggc actgggcacg cggcgcatgg cacgcaagaa cgccatcgtg 1150

 cgaagcctgc cgtccgtgga gaccctgggc tgcacctcag tcatctgctc 1200

 cgacaagacg ggcacgctca ccaccaatca gatgtctgtc tgccggatgt 1250

 tcgtggtagc cgaggccgat gcgggctcct gccttttgca cgagttcacc 1300

 atctcgggta ccacgtatac ccccgagggc gaagtgcggc agggggatca 1350

 gcctgtgcgc tgcggccagt tcgacgggct ggtggagctg gcgaccatct 1400

 gcgccctgtg caacgactcg gctctggact acaacgaggc caagggtgtg 1450

 tatgagaagg tgggagaggc cacggagaca gctctgactt gcctggtgga 1500

 gaagatgaac gtgttcgaca ccgacctgca ggctctgtcc cgggtggagc 1550

 gagctggcgc ctgtaacacg gtcatcaagc agctgatgcg gaaggagttc 1600

 accctggagt tctcccgaga ccggaaatcc atgtccgtgt actgcacgcc 1650

 cacccgccct caccctactg gccagggcag caagatgttt gtgaaggggg 1700

 ctcctgagag tgtgatcgag cgctgtagct cagtccgcgt ggggagccgc 1750

 acagcacccc tgacccccac ctccagggag cagatcctgg caaagatccg 1800

 ggattggggc tcaggctcag acacgctgcg ctgcctggca ctggccaccc 1850

 gggacgcgcc cccaaggaag gaggacatgg agctggacga ctgcagcaag 1900

 tttgtgcagt acgagacgga cctgaccttc gtgggctgcg taggcatgct 1950

 ggacccgccg cgacctgagg tggctgcctg catcacacgc tgctaccagg 2000

 cgggcatccg cgtggtcatg atcacggggg ataacaaagg cactgccgtg 2050

 gccatctgcc gcaggcttgg catctttggg gacacggaag acgtggcggg 2100

 caaggcctac acgggccgcg agtttgatga cctcagcccc gagcagcagc 2150

 gccaggcctg ccgcaccgcc cgctgcttcg cccgcgtgga gcccgcacac 2200

 aagtcccgca tcgtggagaa cctgcagtcc tttaacgaga tcactgctat 2250

 gactggcgat ggagtgaacg acgcaccagc cctgaagaaa gcagagatcg 2300

 gcatcgccat gggctcaggc acggccgtgg ccaagtcggc ggcagagatg 2350

 gtgctgtcag atgacaactt tgcctccatc gtggctgcgg tggaggaggg 2400

 ccgggccatc tacagcaaca tgaagcaatt catccgctac ctcatctcct 2450

 ccaatgttgg cgaggtcgtc tgcatcttcc tcacggcaat tctgggcctg 2500

 cccgaagccc tgatccctgt gcagctgctc tgggtgaacc tggtgacaga 2550

 cggcctacct gccacggctc tgggcttcaa cccgccagac ctggacatca 2600

 tggagaagct gccccggagc ccccgagaag ccctcatcag tggctggctc 2650

 ttcttccgat acctggctat cggagtgtac gtaggcctgg ccacagtggc 2700

 tgccgccacc tggtggtttg tgtatgacgc cgagggacct cacatcaact 2750

 tctaccagct gaggaacttc ctgaagtgct ccgaagacaa cccgctcttt 2800

 gccggcatcg actgtgaggt gttcgagtca cgcttcccca ccaccatggc 2850

 cttgtccgtg ctcgtgacca ttgaaatgtg caatgccctc aacagcgtct 2900

 cggagaacca gtcgctgctg cggatgccgc cctggatgaa cccctggctg 2950

 ctggtggctg tggccatgtc catggccctg cacttcctca tcctgctcgt 3000

 gccgcccctg cctctcattt tccaggtgac cccactgagc gggcgccagt 3050

 gggtggtggt gctccagata tctctgcctg tcatcctgct ggatgaggcc 3100

 ctcaagtacc tgtcccggaa ccacatgcac gcctgtcttt atccaggcct 3150

 tctcaggaca gtctcgcagg cctggagtag gcagccgctg accacctctt 3200

 ggaccccaga ccacaccggg ttggcctctt tgggccaggg acacagcatc 3250

 gtctcgctgt cagagctgct cagagaggga ggaagcaggg aagaaatgag 3300

 ccagaagtga gcgctgggaa cagagtggag tctccggtgt gtacctcaga 3350

 ctgatggtgc ccatgtgttc gcctccgccc cccacccttg ccaccacact 3400

 cgcccacttg cccaccgggt cccgccggat aaatgacagg cccgaggtca 3450

 gaatggccat ccccgggccc cgtcctgggg tctctgtccc cacttccttc 3500

 tggcctggga ggtctgtaat tcctgtctcc tggactctcc tgggaagttc 3550

 cctgctctgc agctctggcc caggagctgc aggctgggag ggggcagcca 3600

 agaagccgga gctggcagca tacccagaga tccggggccc ccccaccccc 3650

 aaatcacgag tgcagctgga gcttgctccc ccttgttcgg aagctggacg 3700

 ttcacttggt gactggtgcc tctgcactga cggaggactc tgggggtcct 3750

 tcttaccggc tctgacctct ctcttcgtgc ctggtctggg actgggtcag 3800

 ccctggggga tcagaagggg ccatctgggc ccagctgtgt acagcgaggg 3850

 tgggcagccc cctccactcc actctgcttc cacaaagtcg gctcccgaga 3900

 gctcgaggct gcttctgttt atatgtgcag ggcccgggcg ggtgaagggt 3950

 cagagagacg gacacaagga gccggcagga gggcggagcg aggatgtcct 4000

 ttcccgggag acaagtcggg aaagcctggc tggactgcct cagccccgcg 4050

 cgcctcctgg actcagggtt ccccgtcctg agctcgggag atgttcagag 4100

 tcacactgcc gcccggtctg ccacgcagag gtccaacttg ccacccgcgt 4150

 ccctggtacc tgagaccacc gacatcctca ggttcctgac cgtggcgccc 4200

 ttctacccag cccagtgtgc ggccgccgcg ctgtctgcac agctgggggc 4250

 ctctgagcct ggtgggcttc ctggactctt ggcctcactc cttgccccct 4300

 ccccacgaca cccatgagcc gaaaggatgt cactaaggat ggctgattcc 4350

 ccaagggcac ccgctctccc tccctccctg ctggaggaac acgtcatatc 4400

 agatgagagg aagatggcct ctgatggaca gaatttttct cttaactcag 4450

 cttttgctac tttggcaaaa actagcgagg ggtagcagaa acctgcacca 4500

 aggattgtcc ctatgtcttg gccactccta gagcgtgtgc agactgatga 4550

 ttttatatgt aaatcaagac tcacatccct ttcctagtcc cccacatcca 4600

 aagcccctca gcctgccttg cagaccaatg ggctccatgt tctgtagccc 4650

 cctcccctac gcctcacccc tcctccctct cacaggttct gggcggccag 4700

 tgagagaaac gcagtggggg aggcagggag tctggtgcct gcagagattc 4750

 tctgcttctt tcctgggggg aggtggggag gtcttagcag gagcgggccc 4800

 tgtacccacc tgctgacctg ctgtttggta gagaaataaa ggttgtgtga 4850

 ctggggg 4857

<210> 2714
<211> 1052
<212> PRT
<213> Homo sapien

<400> 2714
 Met Glu Ala Ala His Leu Leu Pro Ala Ala Asp Val Leu Arg His
   1               5                  10                  15

 Phe Ser Val Thr Ala Glu Gly Gly Leu Ser Pro Ala Gln Val Thr
                  20                  25                  30

 Gly Ala Arg Glu Arg Tyr Gly Pro Asn Glu Leu Pro Ser Glu Glu
                  35                  40                  45

 Gly Lys Ser Leu Trp Glu Leu Val Leu Glu Gln Phe Glu Asp Leu
                  50                  55                  60

 Leu Val Arg Ile Leu Leu Leu Ala Ala Leu Val Ser Phe Val Leu
                  65                  70                  75

 Ala Trp Phe Glu Glu Gly Glu Glu Thr Thr Thr Ala Phe Val Glu
                  80                  85                  90

 Pro Leu Val Ile Met Leu Ile Leu Val Ala Asn Ala Ile Val Gly
                  95                 100                 105

 Val Trp Gln Glu Arg Asn Ala Glu Ser Ala Ile Glu Ala Leu Lys
                 110                 115                 120

 Glu Tyr Glu Pro Glu Met Gly Lys Val Ile Arg Ser Asp Arg Lys
                 125                 130                 135

 Gly Val Gln Arg Ile Arg Ala Arg Asp Ile Val Pro Gly Asp Ile
                 140                 145                 150

 Val Glu Val Ala Val Gly Asp Lys Val Pro Ala Asp Leu Arg Leu
                 155                 160                 165

 Ile Glu Ile Lys Ser Thr Thr Leu Arg Val Asp Gln Ser Ile Leu
                 170                 175                 180

 Thr Gly Glu Ser Val Ser Val Thr Lys His Thr Glu Ala Ile Pro
                 185                 190                 195

 Asp Pro Arg Ala Val Asn Gln Asp Lys Lys Asn Met Leu Phe Ser
                 200                 205                 210

 Gly Thr Asn Ile Thr Ser Gly Lys Ala Val Gly Val Ala Val Ala
                 215                 220                 225

 Thr Gly Leu His Thr Glu Leu Gly Lys Ile Arg Ser Gln Met Ala
                 230                 235                 240

 Ala Val Glu Pro Glu Arg Thr Pro Leu Gln Arg Lys Leu Asp Glu
                 245                 250                 255

 Phe Gly Arg Gln Leu Ser His Ala Ile Ser Val Ile Cys Val Ala
                 260                 265                 270

 Val Trp Val Ile Asn Ile Gly His Phe Ala Asp Pro Ala His Gly
                 275                 280                 285

 Gly Ser Trp Leu Arg Gly Ala Val Tyr Tyr Phe Lys Ile Ala Val
                 290                 295                 300

 Ala Leu Ala Val Ala Ala Ile Pro Glu Gly Leu Pro Ala Val Ile
                 305                 310                 315

 Thr Thr Cys Leu Ala Leu Gly Thr Arg Arg Met Ala Arg Lys Asn
                 320                 325                 330

 Ala Ile Val Arg Ser Leu Pro Ser Val Glu Thr Leu Gly Cys Thr
                 335                 340                 345

 Ser Val Ile Cys Ser Asp Lys Thr Gly Thr Leu Thr Thr Asn Gln
                 350                 355                 360

 Met Ser Val Cys Arg Met Phe Val Val Ala Glu Ala Asp Ala Gly
                 365                 370                 375

 Ser Cys Leu Leu His Glu Phe Thr Ile Ser Gly Thr Thr Tyr Thr
                 380                 385                 390

 Pro Glu Gly Glu Val Arg Gln Gly Asp Gln Pro Val Arg Cys Gly
                 395                 400                 405

 Gln Phe Asp Gly Leu Val Glu Leu Ala Thr Ile Cys Ala Leu Cys
                 410                 415                 420

 Asn Asp Ser Ala Leu Asp Tyr Asn Glu Ala Lys Gly Val Tyr Glu
                 425                 430                 435

 Lys Val Gly Glu Ala Thr Glu Thr Ala Leu Thr Cys Leu Val Glu
                 440                 445                 450

 Lys Met Asn Val Phe Asp Thr Asp Leu Gln Ala Leu Ser Arg Val
                 455                 460                 465

 Glu Arg Ala Gly Ala Cys Asn Thr Val Ile Lys Gln Leu Met Arg
                 470                 475                 480

 Lys Glu Phe Thr Leu Glu Phe Ser Arg Asp Arg Lys Ser Met Ser
                 485                 490                 495

 Val Tyr Cys Thr Pro Thr Arg Pro His Pro Thr Gly Gln Gly Ser
                 500                 505                 510

 Lys Met Phe Val Lys Gly Ala Pro Glu Ser Val Ile Glu Arg Cys
                 515                 520                 525

 Ser Ser Val Arg Val Gly Ser Arg Thr Ala Pro Leu Thr Pro Thr
                 530                 535                 540

 Ser Arg Glu Gln Ile Leu Ala Lys Ile Arg Asp Trp Gly Ser Gly
                 545                 550                 555

 Ser Asp Thr Leu Arg Cys Leu Ala Leu Ala Thr Arg Asp Ala Pro
                 560                 565                 570

 Pro Arg Lys Glu Asp Met Glu Leu Asp Asp Cys Ser Lys Phe Val
                 575                 580                 585

 Gln Tyr Glu Thr Asp Leu Thr Phe Val Gly Cys Val Gly Met Leu
                 590                 595                 600

 Asp Pro Pro Arg Pro Glu Val Ala Ala Cys Ile Thr Arg Cys Tyr
                 605                 610                 615

 Gln Ala Gly Ile Arg Val Val Met Ile Thr Gly Asp Asn Lys Gly
                 620                 625                 630

 Thr Ala Val Ala Ile Cys Arg Arg Leu Gly Ile Phe Gly Asp Thr
                 635                 640                 645

 Glu Asp Val Ala Gly Lys Ala Tyr Thr Gly Arg Glu Phe Asp Asp
                 650                 655                 660

 Leu Ser Pro Glu Gln Gln Arg Gln Ala Cys Arg Thr Ala Arg Cys
                 665                 670                 675

 Phe Ala Arg Val Glu Pro Ala His Lys Ser Arg Ile Val Glu Asn
                 680                 685                 690

 Leu Gln Ser Phe Asn Glu Ile Thr Ala Met Thr Gly Asp Gly Val
                 695                 700                 705

 Asn Asp Ala Pro Ala Leu Lys Lys Ala Glu Ile Gly Ile Ala Met
                 710                 715                 720

 Gly Ser Gly Thr Ala Val Ala Lys Ser Ala Ala Glu Met Val Leu
                 725                 730                 735

 Ser Asp Asp Asn Phe Ala Ser Ile Val Ala Ala Val Glu Glu Gly
                 740                 745                 750

 Arg Ala Ile Tyr Ser Asn Met Lys Gln Phe Ile Arg Tyr Leu Ile
                 755                 760                 765

 Ser Ser Asn Val Gly Glu Val Val Cys Ile Phe Leu Thr Ala Ile
                 770                 775                 780

 Leu Gly Leu Pro Glu Ala Leu Ile Pro Val Gln Leu Leu Trp Val
                 785                 790                 795

 Asn Leu Val Thr Asp Gly Leu Pro Ala Thr Ala Leu Gly Phe Asn
                 800                 805                 810

 Pro Pro Asp Leu Asp Ile Met Glu Lys Leu Pro Arg Ser Pro Arg
                 815                 820                 825

 Glu Ala Leu Ile Ser Gly Trp Leu Phe Phe Arg Tyr Leu Ala Ile
                 830                 835                 840

 Gly Val Tyr Val Gly Leu Ala Thr Val Ala Ala Ala Thr Trp Trp
                 845                 850                 855

 Phe Val Tyr Asp Ala Glu Gly Pro His Ile Asn Phe Tyr Gln Leu
                 860                 865                 870

 Arg Asn Phe Leu Lys Cys Ser Glu Asp Asn Pro Leu Phe Ala Gly
                 875                 880                 885

 Ile Asp Cys Glu Val Phe Glu Ser Arg Phe Pro Thr Thr Met Ala
                 890                 895                 900

 Leu Ser Val Leu Val Thr Ile Glu Met Cys Asn Ala Leu Asn Ser
                 905                 910                 915

 Val Ser Glu Asn Gln Ser Leu Leu Arg Met Pro Pro Trp Met Asn
                 920                 925                 930

 Pro Trp Leu Leu Val Ala Val Ala Met Ser Met Ala Leu His Phe
                 935                 940                 945

 Leu Ile Leu Leu Val Pro Pro Leu Pro Leu Ile Phe Gln Val Thr
                 950                 955                 960

 Pro Leu Ser Gly Arg Gln Trp Val Val Val Leu Gln Ile Ser Leu
                 965                 970                 975

 Pro Val Ile Leu Leu Asp Glu Ala Leu Lys Tyr Leu Ser Arg Asn
                 980                 985                 990

 His Met His Ala Cys Leu Tyr Pro Gly Leu Leu Arg Thr Val Ser
                 995                1000                1005

 Gln Ala Trp Ser Arg Gln Pro Leu Thr Thr Ser Trp Thr Pro Asp
                1010                1015                1020

 His Thr Gly Leu Ala Ser Leu Gly Gln Gly His Ser Ile Val Ser
                1025                1030                1035

 Leu Ser Glu Leu Leu Arg Glu Gly Gly Ser Arg Glu Glu Met Ser
                1040                1045                1050

 Gln Lys


<210> 2715
<211> 1988
<212> DNA
<213> Homo sapien

<400> 2715
 catgctgcgc cgctacctag cctcggaccc cgactgccgc tggtgcccgg 50

 ccccggactg cggttatgct gttattgcct atggctgtgc cagctgcccg 100

 aagctaactt gtgagaggga aggttgccag actgagttct gctaccactg 150

 caagcagata tggcatccaa atcagacatg cgatatggcc cgtcaacaga 200

 gggcccagac tttacgagtt cggaccaaac acacttcagg tctcagttat 250

 gggcaagaat ctggaccagc agatgacgtc aagccatgcc cacgatgcag 300

 tgcatacatt atcaagatga atgatggaag ctgtaatcac atgacctgtg 350

 cagtgtgtgg ctgtgaattc tgttggcttt gtatgaaaga gatctcagac 400

 ttgcattacc tcagcccctc tggctgtaca ttctggggca agaagccatg 450

 gagccgtaag aagaaaattc tttggcagct gggcacgttg attggtgctc 500

 cagtggggat ttctctcatt gctggcattg ccattcctgc catggtcatt 550

 ggcattcctg tttatgttgg aaggaagatt cacagcaggt atgagggaag 600

 gaaaacctcc aaacacaaga ggaatttggc tatcactgga ggagtgactt 650

 tgtcggtcat tgcatcccca gttattgctg cagttagtgt tggtattggt 700

 gtccccatta tgctggcata tgtttatggg gttgtgccca tttctctttg 750

 tcgtggaggc ggctgtggag ttagcacagc caacggaaaa ggagtgaaaa 800

 ttgaatttga tgaagatgat ggtccaatca cagtggcaga tgcctggaga 850

 gccctcaaga atcccagcat tggggaaagc agcattgaag gcctgactag 900

 tgtattgagc actagtggaa gccctacaga tggacttagt gttatgcaag 950

 gtccttacag cgaaacggcc agctttgcag ccctctcagg gggcacgctg 1000

 agtggcggca ttctctccag tggcaaggga aaatatagca ggttagaagt 1050

 tcaagccgat gtccaaaagg aaattttccc caaagacaca gccagtcttg 1100

 gtgcaattag tgacaacgca agcactcgtg ctatggccgg ttccataatc 1150

 agttcctaca acccacagga cagagaatgc aacaatatgg aaatccaagt 1200

 ggacattgaa gccaaaccaa gccactatca gctggtgagt ggaagcagca 1250

 cggaggactc gctccatgtt catgctcaga tggcagagaa tgaagaagaa 1300

 ggtagtggtg gcggaggcag tgaagaggat cccccctgca gacaccaaag 1350

 ctgtgaacag aaagactgcc tggccagcaa accttgggac atcagcctgg 1400

 cccagcctga aagcatccgc agtgacctag agagttctga tgcacagtca 1450

 gacgatgtgc cagacatcac ctcagatgag tgtggctccc cccgctccca 1500

 tactgcagcc tgcccctcga cccccagagc ccaaggtgca ccgagcccaa 1550

 gtgcccatat gaacctctct gccctagccg agggacaaac tgtcttgaag 1600

 ccagaaggtg gagaagccag agtatgaagt ggaatgaatg ctcctgttct 1650

 gagaagcaca cttgtaactg catcttttgg aatttttttt tttttttttt 1700

 ccaaggggta gagatttatg tattttattt cacagattct ctggtcacag 1750

 gtttttgccc agggaaattc tgagaaattc acaatttctt accagataaa 1800

 acatgaaaag tttgccgtta gttcccctcc cctcccctcc ctctttttag 1850

 ttttaattta ttggttaaac tgatggcagc aatccatgag gtgtgtcaaa 1900

 gagtgtacat atgtatgtgt gtatattgaa tgctaaacat attactgaaa 1950

 gacacatttt aataaagatt tctgtcataa ttcaactt 1988

<210> 2716
<211> 541
<212> PRT
<213> Homo sapien

<400> 2716
 Met Leu Arg Arg Tyr Leu Ala Ser Asp Pro Asp Cys Arg Trp Cys
   1               5                  10                  15

 Pro Ala Pro Asp Cys Gly Tyr Ala Val Ile Ala Tyr Gly Cys Ala
                  20                  25                  30

 Ser Cys Pro Lys Leu Thr Cys Glu Arg Glu Gly Cys Gln Thr Glu
                  35                  40                  45

 Phe Cys Tyr His Cys Lys Gln Ile Trp His Pro Asn Gln Thr Cys
                  50                  55                  60

 Asp Met Ala Arg Gln Gln Arg Ala Gln Thr Leu Arg Val Arg Thr
                  65                  70                  75

 Lys His Thr Ser Gly Leu Ser Tyr Gly Gln Glu Ser Gly Pro Ala
                  80                  85                  90

 Asp Asp Val Lys Pro Cys Pro Arg Cys Ser Ala Tyr Ile Ile Lys
                  95                 100                 105

 Met Asn Asp Gly Ser Cys Asn His Met Thr Cys Ala Val Cys Gly
                 110                 115                 120

 Cys Glu Phe Cys Trp Leu Cys Met Lys Glu Ile Ser Asp Leu His
                 125                 130                 135

 Tyr Leu Ser Pro Ser Gly Cys Thr Phe Trp Gly Lys Lys Pro Trp
                 140                 145                 150

 Ser Arg Lys Lys Lys Ile Leu Trp Gln Leu Gly Thr Leu Ile Gly
                 155                 160                 165

 Ala Pro Val Gly Ile Ser Leu Ile Ala Gly Ile Ala Ile Pro Ala
                 170                 175                 180

 Met Val Ile Gly Ile Pro Val Tyr Val Gly Arg Lys Ile His Ser
                 185                 190                 195

 Arg Tyr Glu Gly Arg Lys Thr Ser Lys His Lys Arg Asn Leu Ala
                 200                 205                 210

 Ile Thr Gly Gly Val Thr Leu Ser Val Ile Ala Ser Pro Val Ile
                 215                 220                 225

 Ala Ala Val Ser Val Gly Ile Gly Val Pro Ile Met Leu Ala Tyr
                 230                 235                 240

 Val Tyr Gly Val Val Pro Ile Ser Leu Cys Arg Gly Gly Gly Cys
                 245                 250                 255

 Gly Val Ser Thr Ala Asn Gly Lys Gly Val Lys Ile Glu Phe Asp
                 260                 265                 270

 Glu Asp Asp Gly Pro Ile Thr Val Ala Asp Ala Trp Arg Ala Leu
                 275                 280                 285

 Lys Asn Pro Ser Ile Gly Glu Ser Ser Ile Glu Gly Leu Thr Ser
                 290                 295                 300

 Val Leu Ser Thr Ser Gly Ser Pro Thr Asp Gly Leu Ser Val Met
                 305                 310                 315

 Gln Gly Pro Tyr Ser Glu Thr Ala Ser Phe Ala Ala Leu Ser Gly
                 320                 325                 330

 Gly Thr Leu Ser Gly Gly Ile Leu Ser Ser Gly Lys Gly Lys Tyr
                 335                 340                 345

 Ser Arg Leu Glu Val Gln Ala Asp Val Gln Lys Glu Ile Phe Pro
                 350                 355                 360

 Lys Asp Thr Ala Ser Leu Gly Ala Ile Ser Asp Asn Ala Ser Thr
                 365                 370                 375

 Arg Ala Met Ala Gly Ser Ile Ile Ser Ser Tyr Asn Pro Gln Asp
                 380                 385                 390

 Arg Glu Cys Asn Asn Met Glu Ile Gln Val Asp Ile Glu Ala Lys
                 395                 400                 405

 Pro Ser His Tyr Gln Leu Val Ser Gly Ser Ser Thr Glu Asp Ser
                 410                 415                 420

 Leu His Val His Ala Gln Met Ala Glu Asn Glu Glu Glu Gly Ser
                 425                 430                 435

 Gly Gly Gly Gly Ser Glu Glu Asp Pro Pro Cys Arg His Gln Ser
                 440                 445                 450

 Cys Glu Gln Lys Asp Cys Leu Ala Ser Lys Pro Trp Asp Ile Ser
                 455                 460                 465

 Leu Ala Gln Pro Glu Ser Ile Arg Ser Asp Leu Glu Ser Ser Asp
                 470                 475                 480

 Ala Gln Ser Asp Asp Val Pro Asp Ile Thr Ser Asp Glu Cys Gly
                 485                 490                 495

 Ser Pro Arg Ser His Thr Ala Ala Cys Pro Ser Thr Pro Arg Ala
                 500                 505                 510

 Gln Gly Ala Pro Ser Pro Ser Ala His Met Asn Leu Ser Ala Leu
                 515                 520                 525

 Ala Glu Gly Gln Thr Val Leu Lys Pro Glu Gly Gly Glu Ala Arg
                 530                 535                 540

 Val


<210> 2717
<211> 4783
<212> DNA
<213> Homo sapien

<400> 2717
 cgggagccca ggcgggcagg ccgctggggt cggggctgca cgtacgagag 50

 ccgggacgcc cgggttcaga gcgaaggagg aggcatggct tcggtgttca 100

 tgtgtggcgt ggaggacctg ctgttcagcg gcagccgctt cgtatggaac 150

 ttgaccgtgt ccacgctgcg gagatggtac acggagaggc tgcgggcttg 200

 ccaccaggtg ctgcggacgt ggtgcgggct gcaggacgtg taccagatga 250

 cagaaggcag gcactgccag gtgcacctcc tggatgatag gagactggag 300

 ctgctggttc agcccaaact tctagcaaga gagttgctgg acctagtggc 350

 ttcacatttc aacctgaaag aaaaggagta ttttggaata acattcatag 400

 atgacacagg tcagcagaac tggctgcagt tagatcaccg agttcttgac 450

 cacgatttgc ccaagaaacc aggcccaacc attttgcact ttgctgtgag 500

 gttttacatt gagagcatat cgtttttaaa ggataaaacc accgtggagc 550

 tgtttttcct gaatgcaaag gcctgtgtgc acaaggggca aatcgaagta 600

 gagagcgaaa ccatcttcaa gttagcagcg tttattttac aggaagccaa 650

 gggagattat accagtgatg aaaatgccag gaaagattta aagacattac 700

 cagcctttcc aaccaaaact cttcaggagc atccatccct tgcctactgt 750

 gaggacaggg taattgagca ttatttgaaa atcaaaggtc tcactcgagg 800

 tcaagctgtg gttcagtata tgaaaatagt agaagctcta ccgacttacg 850

 gtgtccatta ttatgcagta aaggataagc aaggacttcc ttggtggctt 900

 ggaataagct ataagggaat tggccaatat gatatacaag acaaggtgaa 950

 gcctcggaag ttattccaat ggaaacagct ggagaactta tatttccgtg 1000

 agaaaaaatt tgctgttgaa gttcatgatc cacgaaggat ttcagtttca 1050

 agaagaacct ttgggcaaag tggcctgttt gtgcaaacat ggtatgctaa 1100

 ctcttctctc atcaagtcca tttgggtaat ggcaattagt cagcatcagt 1150

 tttacttgga ccggaagcaa agcaaagcaa aaattccttc agccaggagt 1200

 ttagatgaga ttgcaatgga tttgacagag acaggaacac aaagggcctc 1250

 caagctggtg acactggagg cgaaaagtca gttcatcatg gcaagtaatg 1300

 gcagtttaat ctcctcaggt tctcaagact cagaagttag tgaagagcaa 1350

 aagagagaaa aaatccttga actaaagaag aaggagaaac tattacaaga 1400

 aaaacttctg aaaaaagttg aggagcttaa gaagatctgt ctgcgggagg 1450

 ctgagctcac aggcaaaatg ccaaaggagt atcccctgaa cataggcgag 1500

 aagcctcctc aggtcagaag acgtgtgggt actgcgttca aattagatga 1550

 caacttgctg ccgagtgaag aagatcctgc tttgcaagaa ctggagagta 1600

 attttctaat acaacaaaag ctggtggaag ctgcaaagaa acttgccaat 1650

 gagccagacc tttgtaaaac tgtgaagaaa aagcgaaagc aagattacac 1700

 agatgcgatg aaaaagcttc aggagattga aaatgcaata aacgaatacc 1750

 gaattaggtg tggaaagaaa cccagccaga aagcaacagt gttaccagaa 1800

 gacataatcc cctcagagag tagctctttg tctgacacca ccacctatga 1850

 tgatcccagt gatgccttca cttttcctgg gcagcgatca agttcagtac 1900

 ctcattctcc aagaattctt ccccccaagt ctcttggtat tgagcgaatc 1950

 catttcagaa agtcgtccat caatgaacag tttgtggata ccaggcagtc 2000

 cagagaaatg ctgtccacac acagcagccc ttacaaaact ctggagaggc 2050

 ggccccaggg aggacgaagc atgcccacca cgccagttct tacccgaaac 2100

 gcctacagca gcagccactt ggaacccgaa tcttcatctc agcactgccg 2150

 ccagcggagt ggaagcctgg agtcccagtc ccatctgctc tccgagatgg 2200

 acagcgataa gccatttttc tccctctcca aatcccaaag aagcagcagc 2250

 acagaaatcc tcgatgacgg gtcttcttat acaagccaat caagcacaga 2300

 gtattactgt gtgacaccag ttaccggccc ctattacacc acccagaccc 2350

 tggacactcg caccaggggt cggaggaggt caaagaaaca gaatgtttct 2400

 acttcaaatt caggaagcat gcccaaccta gcacaaaagg atagtttgag 2450

 gaatggtgtt tactcaaaga gtcaggagcc accgtcttcc agttactaca 2500

 ttgccgggta cacaccctat gcagagtgtg acttttatta cagtggtggt 2550

 tatgtctatg agaatgacac cgagggacag tatagtgtca acccttccta 2600

 ccggtcctca gcccactatg gatatgagcg ccagagggac tacagcagat 2650

 cctttcacga agatgaggtc gaccgggtac cccataaccc atatgcaact 2700

 ctccggctgc caaggaaggc tgctgcaaaa tcggagcaca tcaccaaaaa 2750

 catccacaag gccttagttg ccgagcactt gcgtggctgg taccagcggg 2800

 cctctgggca gaaggatcag ggacacagcc cgcagaccag ctttgactca 2850

 gacaggggat cacagagatg cctggggttt gcggggctgc aagtaccttg 2900

 ttctccaagc agtcgtgcat ccttgtactc ttcagtgtct tctacaaatg 2950

 cttctgggaa ctggaggacc cagttaacca tagggctgtc ggattacgag 3000

 actccagcac attcttctta caccagctgc tatggcaatg tctataatcc 3050

 tttaccctct ccaagcagac aatacacaga aatcagtcaa ctggatggta 3100

 cagatggaaa ccagctggaa gacaacctgg agagtagtga gcagagactc 3150

 ttttggcatg aagattcaaa gcctggaaca ttagtctgaa ctgcagttgg 3200

 acctcctgac caagcactgc gttctcacac tagtgtgcct tgcaaattgt 3250

 atttgtcttc cgagaggatg ttcgttttag aaacctaaag acatcaaagg 3300

 ttgaagagaa gacttagttg ccctggaagt gaatcagtga atcacacacc 3350

 aagccccaca aagcccctaa aggaggattt ggcctttcaa actctaggca 3400

 ctaacgtaac tgtagggtct gcccacatgt tgaagtattg ccaagagagg 3450

 actcagtgtg aagccttcat caatagcaag cactttttaa gggagtaaaa 3500

 gttgttaaag gcaaacgtca aaaacatgaa agggcattca ggatgtccca 3550

 tggcaataag aacaggggaa atctcagagc acaattcagc aggatgagag 3600

 aaggggaacc agaagctccg gagtcattgc tcacttcaga gtttgaattc 3650

 gtgagctgac aaagagtaac atgctctttc tacacagaca tggacaattt 3700

 agacagtatt ggaaaattac ttgaagctgg attttcatga agttctgaat 3750

 gagtgtaaat gttttttagg atactataaa gagtgatgtt tttcataagc 3800

 accataaaat gggttctgga aaaactgatt accttagcat cctgtaatat 3850

 aacttatggt agcagattgg ggaaaatgaa gcagcccact gaataattga 3900

 caaagtctgc ttggagaaca ttctaaggta caatatcatg gagctccttt 3950

 ttcctttctc cactaattgc gtgatgagct attgttctgg ctggtaattc 4000

 tccaactcgg ctgtcatttg aagtggcaga cttaatatgg aaagttttta 4050

 taattatgag tttgaaaaag cattttaaga tgatacagaa agtatccaaa 4100

 acaacagaaa aaaaaagcca cgtcatttta gatgaattgc gtgccttaaa 4150

 atggtgaacg ttagaaaatt aaacaagtct ggattccaca agtagttcca 4200

 agtcaccaag tgacaaaaac aaggttaaca ttaaaaaaga aaaacaacaa 4250

 caacgacaaa aagctccaag ctgcagtgga tttaattatg aggctaaaac 4300

 tacctcatac tttccttgga agaactaatt agctatggtt tattgtaggg 4350

 ttttgtttgt ttgtttttta aagcaaatga tttccatatt cctgattgat 4400

 cttttttgtc atctttgctt caaaattaca taaaaggtgc tcctttcccc 4450

 cttcttttat acaagtttct tgttcatatt gtgaatagaa aagtttctga 4500

 acaacttttt tggaacattt tctatctata ttccaaagca tgtaatatat 4550

 acataaaaac gatttgttaa actggtcctt agtcatttgt ataattagaa 4600

 atgaagtttg ggaaaaaatt ttggaaaaaa gacaagcaaa aaaaaaataa 4650

 cttattcctt ttttgcatat ttgtatagcc ttctagaatc agaaataacc 4700

 tttttgcata ttcttttatt gttctgactt ttcaagacct attatttttt 4750

 tacataggtc aataaacaaa aggtgtgcta ctg 4783

<210> 2718
<211> 1062
<212> PRT
<213> Homo sapien

<400> 2718
 Arg Glu Pro Arg Arg Ala Gly Arg Trp Gly Arg Gly Cys Thr Tyr
   1               5                  10                  15

 Glu Ser Arg Asp Ala Arg Val Gln Ser Glu Gly Gly Gly Met Ala
                  20                  25                  30

 Ser Val Phe Met Cys Gly Val Glu Asp Leu Leu Phe Ser Gly Ser
                  35                  40                  45

 Arg Phe Val Trp Asn Leu Thr Val Ser Thr Leu Arg Arg Trp Tyr
                  50                  55                  60

 Thr Glu Arg Leu Arg Ala Cys His Gln Val Leu Arg Thr Trp Cys
                  65                  70                  75

 Gly Leu Gln Asp Val Tyr Gln Met Thr Glu Gly Arg His Cys Gln
                  80                  85                  90

 Val His Leu Leu Asp Asp Arg Arg Leu Glu Leu Leu Val Gln Pro
                  95                 100                 105

 Lys Leu Leu Ala Arg Glu Leu Leu Asp Leu Val Ala Ser His Phe
                 110                 115                 120

 Asn Leu Lys Glu Lys Glu Tyr Phe Gly Ile Thr Phe Ile Asp Asp
                 125                 130                 135

 Thr Gly Gln Gln Asn Trp Leu Gln Leu Asp His Arg Val Leu Asp
                 140                 145                 150

 His Asp Leu Pro Lys Lys Pro Gly Pro Thr Ile Leu His Phe Ala
                 155                 160                 165

 Val Arg Phe Tyr Ile Glu Ser Ile Ser Phe Leu Lys Asp Lys Thr
                 170                 175                 180

 Thr Val Glu Leu Phe Phe Leu Asn Ala Lys Ala Cys Val His Lys
                 185                 190                 195

 Gly Gln Ile Glu Val Glu Ser Glu Thr Ile Phe Lys Leu Ala Ala
                 200                 205                 210

 Phe Ile Leu Gln Glu Ala Lys Gly Asp Tyr Thr Ser Asp Glu Asn
                 215                 220                 225

 Ala Arg Lys Asp Leu Lys Thr Leu Pro Ala Phe Pro Thr Lys Thr
                 230                 235                 240

 Leu Gln Glu His Pro Ser Leu Ala Tyr Cys Glu Asp Arg Val Ile
                 245                 250                 255

 Glu His Tyr Leu Lys Ile Lys Gly Leu Thr Arg Gly Gln Ala Val
                 260                 265                 270

 Val Gln Tyr Met Lys Ile Val Glu Ala Leu Pro Thr Tyr Gly Val
                 275                 280                 285

 His Tyr Tyr Ala Val Lys Asp Lys Gln Gly Leu Pro Trp Trp Leu
                 290                 295                 300

 Gly Ile Ser Tyr Lys Gly Ile Gly Gln Tyr Asp Ile Gln Asp Lys
                 305                 310                 315

 Val Lys Pro Arg Lys Leu Phe Gln Trp Lys Gln Leu Glu Asn Leu
                 320                 325                 330

 Tyr Phe Arg Glu Lys Lys Phe Ala Val Glu Val His Asp Pro Arg
                 335                 340                 345

 Arg Ile Ser Val Ser Arg Arg Thr Phe Gly Gln Ser Gly Leu Phe
                 350                 355                 360

 Val Gln Thr Trp Tyr Ala Asn Ser Ser Leu Ile Lys Ser Ile Trp
                 365                 370                 375

 Val Met Ala Ile Ser Gln His Gln Phe Tyr Leu Asp Arg Lys Gln
                 380                 385                 390

 Ser Lys Ala Lys Ile Pro Ser Ala Arg Ser Leu Asp Glu Ile Ala
                 395                 400                 405

 Met Asp Leu Thr Glu Thr Gly Thr Gln Arg Ala Ser Lys Leu Val
                 410                 415                 420

 Thr Leu Glu Ala Lys Ser Gln Phe Ile Met Ala Ser Asn Gly Ser
                 425                 430                 435

 Leu Ile Ser Ser Gly Ser Gln Asp Ser Glu Val Ser Glu Glu Gln
                 440                 445                 450

 Lys Arg Glu Lys Ile Leu Glu Leu Lys Lys Lys Glu Lys Leu Leu
                 455                 460                 465

 Gln Glu Lys Leu Leu Lys Lys Val Glu Glu Leu Lys Lys Ile Cys
                 470                 475                 480

 Leu Arg Glu Ala Glu Leu Thr Gly Lys Met Pro Lys Glu Tyr Pro
                 485                 490                 495

 Leu Asn Ile Gly Glu Lys Pro Pro Gln Val Arg Arg Arg Val Gly
                 500                 505                 510

 Thr Ala Phe Lys Leu Asp Asp Asn Leu Leu Pro Ser Glu Glu Asp
                 515                 520                 525

 Pro Ala Leu Gln Glu Leu Glu Ser Asn Phe Leu Ile Gln Gln Lys
                 530                 535                 540

 Leu Val Glu Ala Ala Lys Lys Leu Ala Asn Glu Pro Asp Leu Cys
                 545                 550                 555

 Lys Thr Val Lys Lys Lys Arg Lys Gln Asp Tyr Thr Asp Ala Met
                 560                 565                 570

 Lys Lys Leu Gln Glu Ile Glu Asn Ala Ile Asn Glu Tyr Arg Ile
                 575                 580                 585

 Arg Cys Gly Lys Lys Pro Ser Gln Lys Ala Thr Val Leu Pro Glu
                 590                 595                 600

 Asp Ile Ile Pro Ser Glu Ser Ser Ser Leu Ser Asp Thr Thr Thr
                 605                 610                 615

 Tyr Asp Asp Pro Ser Asp Ala Phe Thr Phe Pro Gly Gln Arg Ser
                 620                 625                 630

 Ser Ser Val Pro His Ser Pro Arg Ile Leu Pro Pro Lys Ser Leu
                 635                 640                 645

 Gly Ile Glu Arg Ile His Phe Arg Lys Ser Ser Ile Asn Glu Gln
                 650                 655                 660

 Phe Val Asp Thr Arg Gln Ser Arg Glu Met Leu Ser Thr His Ser
                 665                 670                 675

 Ser Pro Tyr Lys Thr Leu Glu Arg Arg Pro Gln Gly Gly Arg Ser
                 680                 685                 690

 Met Pro Thr Thr Pro Val Leu Thr Arg Asn Ala Tyr Ser Ser Ser
                 695                 700                 705

 His Leu Glu Pro Glu Ser Ser Ser Gln His Cys Arg Gln Arg Ser
                 710                 715                 720

 Gly Ser Leu Glu Ser Gln Ser His Leu Leu Ser Glu Met Asp Ser
                 725                 730                 735

 Asp Lys Pro Phe Phe Ser Leu Ser Lys Ser Gln Arg Ser Ser Ser
                 740                 745                 750

 Thr Glu Ile Leu Asp Asp Gly Ser Ser Tyr Thr Ser Gln Ser Ser
                 755                 760                 765

 Thr Glu Tyr Tyr Cys Val Thr Pro Val Thr Gly Pro Tyr Tyr Thr
                 770                 775                 780

 Thr Gln Thr Leu Asp Thr Arg Thr Arg Gly Arg Arg Arg Ser Lys
                 785                 790                 795

 Lys Gln Asn Val Ser Thr Ser Asn Ser Gly Ser Met Pro Asn Leu
                 800                 805                 810

 Ala Gln Lys Asp Ser Leu Arg Asn Gly Val Tyr Ser Lys Ser Gln
                 815                 820                 825

 Glu Pro Pro Ser Ser Ser Tyr Tyr Ile Ala Gly Tyr Thr Pro Tyr
                 830                 835                 840

 Ala Glu Cys Asp Phe Tyr Tyr Ser Gly Gly Tyr Val Tyr Glu Asn
                 845                 850                 855

 Asp Thr Glu Gly Gln Tyr Ser Val Asn Pro Ser Tyr Arg Ser Ser
                 860                 865                 870

 Ala His Tyr Gly Tyr Glu Arg Gln Arg Asp Tyr Ser Arg Ser Phe
                 875                 880                 885

 His Glu Asp Glu Val Asp Arg Val Pro His Asn Pro Tyr Ala Thr
                 890                 895                 900

 Leu Arg Leu Pro Arg Lys Ala Ala Ala Lys Ser Glu His Ile Thr
                 905                 910                 915

 Lys Asn Ile His Lys Ala Leu Val Ala Glu His Leu Arg Gly Trp
                 920                 925                 930

 Tyr Gln Arg Ala Ser Gly Gln Lys Asp Gln Gly His Ser Pro Gln
                 935                 940                 945

 Thr Ser Phe Asp Ser Asp Arg Gly Ser Gln Arg Cys Leu Gly Phe
                 950                 955                 960

 Ala Gly Leu Gln Val Pro Cys Ser Pro Ser Ser Arg Ala Ser Leu
                 965                 970                 975

 Tyr Ser Ser Val Ser Ser Thr Asn Ala Ser Gly Asn Trp Arg Thr
                 980                 985                 990

 Gln Leu Thr Ile Gly Leu Ser Asp Tyr Glu Thr Pro Ala His Ser
                 995                1000                1005

 Ser Tyr Thr Ser Cys Tyr Gly Asn Val Tyr Asn Pro Leu Pro Ser
                1010                1015                1020

 Pro Ser Arg Gln Tyr Thr Glu Ile Ser Gln Leu Asp Gly Thr Asp
                1025                1030                1035

 Gly Asn Gln Leu Glu Asp Asn Leu Glu Ser Ser Glu Gln Arg Leu
                1040                1045                1050

 Phe Trp His Glu Asp Ser Lys Pro Gly Thr Leu Val
                1055                1060

<210> 2719
<211> 1418
<212> DNA
<213> Homo sapien

<400> 2719
 agaagaagct ggccaaggat atgggagcaa ccaccatgga ccagaagtct 50

 ctctgggcag gtgtagtggt cttgctgctt ctccagggag gatctgccta 100

 caaactggtt tgctacttta ccaactggtc ccaggaccgg caggaaccag 150

 gaaaattcac ccctgagaat attgacccct tcctatgctc tcatctcatc 200

 tattcattcg ccagcatcga aaacaacaag gttatcatca aggacaagag 250

 tgaagtgatg ctctaccaga ccatcaacag tctcaaaacc aagaatccca 300

 aactgaaaat tctcttgtcc attggagggt acctgtttgg ttccaaaggg 350

 ttccacccta tggtggattc ttctacatca cgcttggaat tcattaactc 400

 cataatcctg tttctgagga accataactt tgatggactg gatgtaagct 450

 ggatctaccc agatcagaaa gaaaacactc atttcactgt gctgattcat 500

 gagttagcag aagcctttca gaaggacttc acaaaatcca ccaaggaaag 550

 gcttctcttg actgcgggcg tatctgcagg gaggcaaatg attgataaca 600

 gctatcaagt tgagaaactg gcaaaagatc tggatttcat caacctcctg 650

 tcctttgact tccatgggtc ttgggaaaag ccccttatca ctggccacaa 700

 cagccctctg agcaaggggt ggcaggacag agggccaagc tcctactaca 750

 atgtggaata tgctgtgggg tactggatac ataagggaat gccatcagag 800

 aaggtggtca tgggcatccc cacatatggg cactccttca cactggcctc 850

 tgcagaaacc accgtggggg cccctgcctc tggccctgga gctgctggac 900

 ccatcacaga gtcttcaggc ttcctggcct attatgagat ctgccagttc 950

 ctgaaaggag ccaagatcac gcgcctccag gatcagcagg ttccctacgc 1000

 agtcaagggg aaccagtggg tgggctatga tgatgtgaag agtatggaga 1050

 ccaaggttca gttcttaaag aatttaaacc tgggaggagc catgatctgg 1100

 tctattgaca tggatgactt cactggcaaa tcctgcaacc agggccctta 1150

 ccctcttgtc caagcagtca agagaagcct tggctccttg tgaaggatta 1200

 acttacagag aagcaggcaa gatgaccttg ctgcctgggg cctgctctct 1250

 cccaggaatt ctcatgtggg attccccttg ccaggctggc ctttggatct 1300

 ctcttccaag cctttcctga cttcctctta gatcatagat tggacctggt 1350

 tttgttttcc tgcagctgtt gacttgttgc cctgaagtac aataaaaaaa 1400

 attcattttg ctccagta 1418

<210> 2720
<211> 385
<212> PRT
<213> Homo sapien

<400> 2720
 Met Asp Gln Lys Ser Leu Trp Ala Gly Val Val Val Leu Leu Leu
   1               5                  10                  15

 Leu Gln Gly Gly Ser Ala Tyr Lys Leu Val Cys Tyr Phe Thr Asn
                  20                  25                  30

 Trp Ser Gln Asp Arg Gln Glu Pro Gly Lys Phe Thr Pro Glu Asn
                  35                  40                  45

 Ile Asp Pro Phe Leu Cys Ser His Leu Ile Tyr Ser Phe Ala Ser
                  50                  55                  60

 Ile Glu Asn Asn Lys Val Ile Ile Lys Asp Lys Ser Glu Val Met
                  65                  70                  75

 Leu Tyr Gln Thr Ile Asn Ser Leu Lys Thr Lys Asn Pro Lys Leu
                  80                  85                  90

 Lys Ile Leu Leu Ser Ile Gly Gly Tyr Leu Phe Gly Ser Lys Gly
                  95                 100                 105

 Phe His Pro Met Val Asp Ser Ser Thr Ser Arg Leu Glu Phe Ile
                 110                 115                 120

 Asn Ser Ile Ile Leu Phe Leu Arg Asn His Asn Phe Asp Gly Leu
                 125                 130                 135

 Asp Val Ser Trp Ile Tyr Pro Asp Gln Lys Glu Asn Thr His Phe
                 140                 145                 150

 Thr Val Leu Ile His Glu Leu Ala Glu Ala Phe Gln Lys Asp Phe
                 155                 160                 165

 Thr Lys Ser Thr Lys Glu Arg Leu Leu Leu Thr Ala Gly Val Ser
                 170                 175                 180

 Ala Gly Arg Gln Met Ile Asp Asn Ser Tyr Gln Val Glu Lys Leu
                 185                 190                 195

 Ala Lys Asp Leu Asp Phe Ile Asn Leu Leu Ser Phe Asp Phe His
                 200                 205                 210

 Gly Ser Trp Glu Lys Pro Leu Ile Thr Gly His Asn Ser Pro Leu
                 215                 220                 225

 Ser Lys Gly Trp Gln Asp Arg Gly Pro Ser Ser Tyr Tyr Asn Val
                 230                 235                 240

 Glu Tyr Ala Val Gly Tyr Trp Ile His Lys Gly Met Pro Ser Glu
                 245                 250                 255

 Lys Val Val Met Gly Ile Pro Thr Tyr Gly His Ser Phe Thr Leu
                 260                 265                 270

 Ala Ser Ala Glu Thr Thr Val Gly Ala Pro Ala Ser Gly Pro Gly
                 275                 280                 285

 Ala Ala Gly Pro Ile Thr Glu Ser Ser Gly Phe Leu Ala Tyr Tyr
                 290                 295                 300

 Glu Ile Cys Gln Phe Leu Lys Gly Ala Lys Ile Thr Arg Leu Gln
                 305                 310                 315

 Asp Gln Gln Val Pro Tyr Ala Val Lys Gly Asn Gln Trp Val Gly
                 320                 325                 330

 Tyr Asp Asp Val Lys Ser Met Glu Thr Lys Val Gln Phe Leu Lys
                 335                 340                 345

 Asn Leu Asn Leu Gly Gly Ala Met Ile Trp Ser Ile Asp Met Asp
                 350                 355                 360

 Asp Phe Thr Gly Lys Ser Cys Asn Gln Gly Pro Tyr Pro Leu Val
                 365                 370                 375

 Gln Ala Val Lys Arg Ser Leu Gly Ser Leu
                 380                 385

<210> 2721
<211> 8511
<212> DNA
<213> Homo sapien

<400> 2721
 gttcgatgaa agaattgccg cttttcaaac aaagagtgga acagcctcgg 50

 agatgggaac agagagggcg atggggctgt cagaagaatg gactgtgcac 100

 agccaagagg ccaccacttc ggcttggagc ccttcctttc ttcctgcttt 150

 ggagatggga gagctgacca cgccttctag gaagagaaat tcctcaggac 200

 cagatctctc ctggctgcat ttctacagga cagcagcttc ctctcctctc 250

 ttagaccttt cctcaccttc tgaaagtaca gagaagctta acaactccac 300

 tggcctccag agctcctcag tcagtcaaac aaagacaatg catgttgcta 350

 ccgtgttcac tgatggtggc ccgagaacgc tgcgatcttt gacggtcagt 400

 ctgggacctg tgagcaagac agaaggcttc cccaaggact ccagaattgc 450

 cacgacttca tcctcagtcc ttctttcacc ctctgcagtg gaatcgagaa 500

 gaaacagtag agtaactggg aatccagggg atgaggaatt cattgaacca 550

 tccacagaaa atgaatttgg acttacgtct ttgcgtggca aaatgattcc 600

 ccaacctttg gagaacatca gcttgccagc agctctgagg tgcaaaatgg 650

 aagtcccatg tctcagactg agactgtgtc taggtcagtc gcacccatga 700

 gaggtggaga gatcactgca cactggctct tgaccaacag cacaacatct 750

 gcagatgtga caggaagctc tgcttcatat cctgaaggtg tgaatgcttc 800

 agtgttgacc cagttctcag actctactgt acagtctgga ggaagtcaca 850

 cagcattggg agataggagt tattcagagt cttcatctac atcttcctcg 900

 gaaagcttga attcatcagc accacgtgga gaacgttcaa tcgctgggat 950

 tagctacggt caagtgcgtg gcacagctat tgaacaaagg acttccagcg 1000

 accacacaga ccacacctac ctgtcatcta ctttcaccaa aggagaacgg 1050

 gcgttactgt ccattacaga taacagttca tcctcagaca ttgtggagag 1100

 ctcaacttct tatattaaaa tctcaaactc ttcacattca gagtattcct 1150

 ccttttttca tgctcagact gagagaagta acatctcatc ctatgacggg 1200

 gaatatgctc agccttctac tgagtcgcca gttctgcata catccaacct 1250

 tccgtcctac acacccacca ttaatatgcc gaacacttcg gttgttctgg 1300

 acactgatgc tgagtttgtt agtgactcct cctcctcctc ttcctcctcc 1350

 tcctcttctt cttcttcagg gcctcctttg cctctgccct ctgtgtcaca 1400

 atcccaccat ttattttcat caattttacc atcaaccagg gcctctgtgc 1450

 atctactaaa gtctacctct gatgcatcca caccatggtc ttcctcacca 1500

 tcacctttac cagtatcctt aacgacatct acatctgccc cactttctgt 1550

 ctcacaaaca accttgccac agtcatcttc tacccctgtc ctgcccaggg 1600

 caagggagac tcctgtgact tcatttcaga catcaacaat gacatcattc 1650

 atgacaatgc tccatagtag tcaaactgca gaccttaaga gccagagcac 1700

 cccacaccaa gagaaagtca ttacagaatc aaagtcacca agcctggtgt 1750

 ctctgcccac agagtccacc aaagctgtaa caacaaactc tcctttgcct 1800

 ccatccttaa cagagtcctc cacagagcaa acccttccag ccacaagcac 1850

 caacttagca caaatgtctc caactttcac aactaccatt ctgaagacct 1900

 ctcagcctct tatgaccact cctggcaccc tgtcaagcac agcatctctg 1950

 gtcactggcc ctatagccgt acagactaca gctggaaaaa cagctctcgc 2000

 tgacccatcc tgaaatacta gttcctcaaa tctcaacaga aggtggcatc 2050

 agcacagaaa ggaaccgagt gattgtggat gctaccactg gattgatccc 2100

 tttgaccagt gtacccacat cagcaaaaga aatgaccaca aagcttggcg 2150

 ttacagcaga gtacagccca gcttcacgtt ccctcggaac atctccttct 2200

 ccccaaacca cagttgtttc cacggctgaa gacttggctc ccaaatctgc 2250

 cacctttgct gttcagagca gcacacagtc accaacaaca ctgtcctctt 2300

 cagcctcagt caacagctgt gctgtgaacc cttgtcttca caatggcgaa 2350

 tgcgtcgcag acaacaccag ccgtggctac cactgcaggt gcccgccttc 2400

 ctggcaaggg gatgattgca gtgtggatgt gaatgagtgc ctgtcgaacc 2450

 cctgcccatc cacagccacg tgcaacaata ctcagggatc ctttatctgc 2500

 aaatgcccgg ttgggtacca gttggaaaaa gggatatgca atttggttag 2550

 aaccttcgtg acagagttta aattaaagag aacttttctt aatacaactg 2600

 tggaaaaaca ttcagaccta caagaagttg aaaatgagat caccaaaacg 2650

 ttaaatatgt gtttttcagc gttacctagt tacatccgat ctacagttca 2700

 cgcctctagg gagtccaacg cggtggtgat ctcactgcaa acaacctttt 2750

 ccctggcctc caatgtgacg ctatttgacc tggctgatag gatgcagaaa 2800

 tgtgtcaact cctgcaagtc ctctgctgag gtctgccagc tcttgggatc 2850

 tcagaggcgg atctttagag cgggcagctt gtgcaagcgg aagagtcccg 2900

 aatgtgacaa agacacctcc atctgcactg acctggacgg cgttgccctg 2950

 tgccagtgca agtcgggata ctttcagttc aacaagatgg accactcctg 3000

 ccgagcatgt gaagatggat ataggcttga aaatgaaacc tgcatgagtt 3050

 gcccatttgg ccttggtggt ctcaactgtg gaaaccccta tcagcttatc 3100

 actgtggtga tcgcagccgc gggaggtggg ctcctgctca tcctaggcat 3150

 cgcactgatt gttacctgtt gcagaaagaa taaaaatgac ataagcaaac 3200

 tcatcttcaa aagtggagat ttccaaatgt ccccatatgc tgaatacccc 3250

 aaaaatcctc gctcacaaga atggggccga gaagctattg aaatgcatga 3300

 gaatggaagt accaaaaacc tcctccagat gacggatgtg tactactcgc 3350

 ctacaagtgt aaggaatcca gaacttgaac gaaacggact ctacccggcc 3400

 tacactggac tgccaggatc acggcattct tgcattttcc ccggacagta 3450

 taacccgtct ttcatcagtg atgaaagcag aagaagagac tacttttaag 3500

 tccaggagag agagggactc attgctctga gccagtcacc tgggacctct 3550

 gctcagagga ccgcaccagg aggctgcgcc caggatttgt cgggagccac 3600

 gctgagtggc aagcaggaag agggacaggc atgcggggcg tgaccacagt 3650

 ggaggagaca ggtggatgtg gaaccacagg ctgctcattc agcacctttg 3700

 ttgttactgt gaacgtgaat gtgggccagt atcaagagag tctctctgag 3750

 tgactgcacc atggcactgg caccagggcg actattagcc agggcagacc 3800

 actagacttc agtgcaggga cctggttttc ccttcgtttg cactttagta 3850

 aattgggtgg gaggtttcct tttggatctg ttttgagact gttccagaaa 3900

 gaaggcttcc tttcccgaga cacttccata ggcagcaatt tggtgattca 3950

 tttgcagcaa aatactggct tgttaattat tttcctgccc agcgcctgcg 4000

 tgctaaacaa cagatgagga tgagcgtacc actgaagtct gaagatgtcg 4050

 ccattgaacg gacagtgttt tcatatgttt ctaggttgtc ttatgctaca 4100

 gtttccaagc cagcccccac agtgaggaaa tgtgtgaggc accgcacaca 4150

 actgcaatgt gttttttaag tcaaggtgac acatgtattt aagatttttt 4200

 tttaaaatct ctttgcagtt aaatctcact ttttcaaaca agcctggatc 4250

 agggcaaaac aacttatatt tggttttagc tggaggctca gcaggcagat 4300

 tgcaggcagg ggggcacttt tcatccatga gggcccagcc tggggcctgg 4350

 gactctgatc accattgtgg aggccagagg cagctgcgta tggaggagaa 4400

 atgtcaaact gaacgcaggt ttcaccactc taggaaagca gcttgttgag 4450

 cccctgcagc tggatgtggt tagagggatg ggctgaatag gcaggttaga 4500

 tttcctgcat caacagtgct ttgggaagct gtgtggattc ctgaggaaga 4550

 acagggagcc gagatggagc cacacatgag tttgctcacc ggctactgca 4600

 gcactttgta cccagaatct catgtccaca aaccccatgt aaactttcaa 4650

 ccactcaaag ctgtttattc ggctgaagaa ataacttttt tttctcaccc 4700

 agtcatttgt acctcttcat atggctatgt cgcaccctcc agaaacgtgg 4750

 ttatacttcc agtcagtgtg ggagaactga agacttccgg ttggtcgagg 4800

 aactgagggt tgaccttcgg gaaggaagtt ccactcatct tatttattat 4850

 gcctgtgatg tgggtcctgc cagggagaca tccagtactc ggtgtcttta 4900

 attgccacct ggggaactgt gtttattggc cttctttggg gcatcctggt 4950

 tttggatgaa gtgaggggaa tacagaggta aaagaattgt ctccaccctg 5000

 aagcggggag tcccgcttca catttctgga aatggtgcag ccactgggga 5050

 cagttctgcc ccgggcatgg ttgtttcttc aaggtcctct aaatataatc 5100

 cctattctta cataatcctt ggccctgatg gttttaagca agaactcctg 5150

 tgtcccatgg tctccaccac tcaccatcac cctgctgtag caagagtcct 5200

 agtcagggga ggtgcatttt agtagttaaa ttgcacttat ccatgagata 5250

 aataaaagga gaactgtttt tatcagtgga ggctaaccta aaatttcaaa 5300

 gtgtcgcctt tttgaaatct tgggcctctc tctctgtaga accaatggcc 5350

 ctttgtggct cacggcctcg cacctaactg gagagttctg agctcctgca 5400

 gctcacctga gcccacagac taggcttctt ggctccttcc gcagcatgcc 5450

 tgctcacccc cagaacccgc agctgtggga agagccatgt agggaggcta 5500

 ttcccaggca tacacttcca ctgccttcag ctgacgtcac agctgacaaa 5550

 tcatctcctc tatcggagcc agaagacttc agctccacaa aatgaagtgt 5600

 tctgtcctga aaacattctt gggaagaatc ccaacatcga gaaaacggtg 5650

 tcctgtgagt tccaacaatg cttcttgttc atgggtttct tccgtatgga 5700

 gtggattaag agtgttttat tttgttgttc taactgagaa aaaaaggagg 5750

 cacccacaag gttgaggtca cacagtctcc acagtttcca ggaggcgttt 5800

 gggggtgggg aaggcacctc cagagcatga ggctctaagg ggacatgagt 5850

 aaagcatgtc tgtgacccag tgaggaaggg agaggccagc tgcactcctg 5900

 cacggggttc ctagctgcag aagggtcccg cctaggccga ggggaaacac 5950

 ctgatagcag aagaggcctg gatgcacacc tggcacgccg aggctctccg 6000

 cccagacaca gtgctccatg tcagcccctg cacctggggt gtgtgattca 6050

 cgtgcacaga tgccacaatc ctgcaccaat atcccacaga tgggggaagg 6100

 tgagaggaag gggcaagtga tgtgtaactg ctcaagagat gcttaaacct 6150

 ccatagagag gagccgggcg caggggcatc tgtgtgtccc gtcacacact 6200

 gcagcaggga agggtggctg gctggctccc tggcatcagt ggtttggttt 6250

 aagctccaga gggtcttatt gccattgtct tttcctctgc cccttgagcc 6300

 agcctaaggc cctggagtct gtttctttag gcggatgaac tgacatgctc 6350

 ctaccatgac caggctctgg gcaaggctcc tcacagtatc cttgagaggt 6400

 gggcatggaa gtgcccattt ctcaggtaca gaaaccttca gagaggataa 6450

 atagcttgcc ctgtagaagc aggactgaaa cccttgtccg cctgactccc 6500

 ccagctactc tgcccactgt agccccctgc cttactgtcc tggcacaccc 6550

 ctcaccatcc tgtatacctt aaatatcaaa gagggcaaga gagaaagggc 6600

 tttaaagata agttattttt ttaaggaacc ttaatattat ttttaagaag 6650

 taaccaaatt agtgacgtga aatgcaaaaa aaaaaaaaaa aaatgctgac 6700

 tacccttttg aaaatgtgct ttcagattgt tttttatgtg taattcttag 6750

 acacttgtca ttaagaaaat agtggctggc ttgtgctcag caagaagcac 6800

 actggcacgt ggctttggta taggaagtgg aaggcaagga cctgggtttc 6850

 tgacaagtgc agtcagacat acacatccat ctgagagctg cttgccttgt 6900

 tcccgtggta aggccatggc tcccacatac tggaagcata tttttgtgaa 6950

 ctgttttcag aattgggaac atattcagtg gaatgtctta aacgctgaca 7000

 catcttcctc ctttgagggg aagtatattt tcagaagcag ctaagacatt 7050

 tagagccaaa attgctgata ggtggttcag tcaagttggc tgatggcatc 7100

 tgaggtcaaa aactaagatg tgacgattga gttcttaaag aggtaactct 7150

 taaagtgggc ccaagggaga aggcagcatc tttggactcc taggctggat 7200

 ggctacccaa gaatatgcca ttgaaggatg acacctattc agatgtgaaa 7250

 gttcccagag caggcacctt tgggtcaccc accacgtgtg gctttttggt 7300

 gcctgcatga aactgtgttg ccccctggtg agatgcccgg gtgtcctgta 7350

 agccgattta actctgcctg aggaagagga gctgtccact ccagttgccc 7400

 ttggctaagt ttagcctaac acacagggtt ttgacccata gttctaaaat 7450

 acacaaattt tgagactaca gcacttcttt ggaaagagga agaatgcaaa 7500

 gttcagtatt tcaatacttt gtattttact tgaaattacc cttagtagca 7550

 tctttttttt cctgtctgaa agcttttgtg tggatgagaa gggacatttc 7600

 atttcctccc ttaacaaagt gtcattctga ggttctcatg tgtgtttttg 7650

 gaaatagaga tactggtttt gtagagtttg cctttgggta tgttttcttt 7700

 ttttcttaaa tctccaagga agagaactga ctaaaatagt aggaacatga 7750

 aagtattaaa tgccaattaa tttgttgtag taaagtatct tcattagcgt 7800

 tatactccat catatctggt gtaaactgct cacagaaaac cctatgaaac 7850

 caaaggggga ccattcaggt ctaaaaagcg acaggtccga gactgggtct 7900

 gtcacctggg cattttcaaa gaggacattt tgaagaattt gcatattcag 7950

 atttttaaaa tgcacttaac atacttcatt acagatttct tgggtaggga 8000

 ggatgggata ggccagggat gggatggaat cagttctgcc tgggaaacta 8050

 atccgaatca tttacctttc tgtattaacc ttggcctgtc ctaaaaagag 8100

 aacgactgtt tcatcatgag ttgctctgag ttttgttaat gtttgtgttg 8150

 gtggattgac ggttaaatga agcatttagc tggaatatga actttgggag 8200

 ttttcatgtt gtcctggatt tctctttgta aacctttaaa ccttagcccc 8250

 tggttgattg tgttaaaccc attatgagaa tgttatttaa agttgtatta 8300

 taattgcaac ctccactaat tattcagtac tgtagcagca aagtattatt 8350

 tgtaagaatt tggttatttt tatacttata tccactctaa gtctggcgtt 8400

 ctagtcagta aaatgatgca ataaaattaa tatcatttta aaaaaatcta 8450

 tgtcgggtgc ggagaaagag gtaatgaaat ggcaggaatt cgatatcagc 8500

 ttatcatacc t 8511

<210> 2722
<211> 1165
<212> PRT
<213> Homo sapien

<400> 2722
 Phe Asp Glu Arg Ile Ala Ala Phe Gln Thr Lys Ser Gly Thr Ala
   1               5                  10                  15

 Ser Glu Met Gly Thr Glu Arg Ala Met Gly Leu Ser Glu Glu Trp
                  20                  25                  30

 Thr Val His Ser Gln Glu Ala Thr Thr Ser Ala Trp Ser Pro Ser
                  35                  40                  45

 Phe Leu Pro Ala Leu Glu Met Gly Glu Leu Thr Thr Pro Ser Arg
                  50                  55                  60

 Lys Arg Asn Ser Ser Gly Pro Asp Leu Ser Trp Leu His Phe Tyr
                  65                  70                  75

 Arg Thr Ala Ala Ser Ser Pro Leu Leu Asp Leu Ser Ser Pro Ser
                  80                  85                  90

 Glu Ser Thr Glu Lys Leu Asn Asn Ser Thr Gly Leu Gln Ser Ser
                  95                 100                 105

 Ser Val Ser Gln Thr Lys Thr Met His Val Ala Thr Val Phe Thr
                 110                 115                 120

 Asp Gly Gly Pro Arg Thr Leu Arg Ser Leu Thr Val Ser Leu Gly
                 125                 130                 135

 Pro Val Ser Lys Thr Glu Gly Phe Pro Lys Asp Ser Arg Ile Ala
                 140                 145                 150

 Thr Thr Ser Ser Ser Val Leu Leu Ser Pro Ser Ala Val Glu Ser
                 155                 160                 165

 Arg Arg Asn Ser Arg Val Thr Gly Asn Pro Gly Asp Glu Glu Phe
                 170                 175                 180

 Ile Glu Pro Ser Thr Glu Asn Glu Ile Trp Thr Tyr Val Phe Ala
                 185                 190                 195

 Trp Gln Asn Asp Ser Pro Thr Phe Gly Glu His Gln Leu Ala Ser
                 200                 205                 210

 Ser Ser Glu Val Gln Asn Gly Ser Pro Met Ser Gln Thr Glu Thr
                 215                 220                 225

 Val Ser Arg Ser Val Ala Pro Met Arg Gly Gly Glu Ile Thr Ala
                 230                 235                 240

 His Trp Leu Leu Thr Asn Ser Thr Thr Ser Ala Asp Val Thr Gly
                 245                 250                 255

 Ser Ser Ala Ser Tyr Pro Glu Gly Val Asn Ala Ser Val Leu Thr
                 260                 265                 270

 Gln Phe Ser Asp Ser Thr Val Gln Ser Gly Gly Ser His Thr Ala
                 275                 280                 285

 Leu Gly Asp Arg Ser Tyr Ser Glu Ser Ser Ser Thr Ser Ser Ser
                 290                 295                 300

 Glu Ser Leu Asn Ser Ser Ala Pro Arg Gly Glu Arg Ser Ile Ala
                 305                 310                 315

 Gly Ile Ser Tyr Gly Gln Val Arg Gly Thr Ala Ile Glu Gln Arg
                 320                 325                 330

 Thr Ser Ser Asp His Thr Asp His Thr Tyr Leu Ser Ser Thr Phe
                 335                 340                 345

 Thr Lys Gly Glu Arg Ala Leu Leu Ser Ile Thr Asp Asn Ser Ser
                 350                 355                 360

 Ser Ser Asp Ile Val Glu Ser Ser Thr Ser Tyr Ile Lys Ile Ser
                 365                 370                 375

 Asn Ser Ser His Ser Glu Tyr Ser Ser Phe Phe His Ala Gln Thr
                 380                 385                 390

 Glu Arg Ser Asn Ile Ser Ser Tyr Asp Gly Glu Tyr Ala Gln Pro
                 395                 400                 405

 Ser Thr Glu Ser Pro Val Leu His Thr Ser Asn Leu Pro Ser Tyr
                 410                 415                 420

 Thr Pro Thr Ile Asn Met Pro Asn Thr Ser Val Val Leu Asp Thr
                 425                 430                 435

 Asp Ala Glu Phe Val Ser Asp Ser Ser Ser Ser Ser Ser Ser Ser
                 440                 445                 450

 Ser Ser Ser Ser Ser Ser Gly Pro Pro Leu Pro Leu Pro Ser Val
                 455                 460                 465

 Ser Gln Ser His His Leu Phe Ser Ser Ile Leu Pro Ser Thr Arg
                 470                 475                 480

 Ala Ser Val His Leu Leu Lys Ser Thr Ser Asp Ala Ser Thr Pro
                 485                 490                 495

 Trp Ser Ser Ser Pro Ser Pro Leu Pro Val Ser Leu Thr Thr Ser
                 500                 505                 510

 Thr Ser Ala Pro Leu Ser Val Ser Gln Thr Thr Leu Pro Gln Ser
                 515                 520                 525

 Ser Ser Thr Pro Val Leu Pro Arg Ala Arg Glu Thr Pro Val Thr
                 530                 535                 540

 Ser Phe Gln Thr Ser Thr Met Thr Ser Phe Met Thr Met Leu His
                 545                 550                 555

 Ser Ser Gln Thr Ala Asp Leu Lys Ser Gln Ser Thr Pro His Gln
                 560                 565                 570

 Glu Lys Val Ile Thr Glu Ser Lys Ser Pro Ser Leu Val Ser Leu
                 575                 580                 585

 Pro Thr Glu Ser Thr Lys Ala Val Thr Thr Asn Ser Pro Leu Pro
                 590                 595                 600

 Pro Ser Leu Thr Glu Ser Ser Thr Glu Gln Thr Leu Pro Ala Thr
                 605                 610                 615

 Ser Thr Asn Leu Ala Gln Met Ser Pro Thr Phe Thr Thr Thr Ile
                 620                 625                 630

 Leu Lys Thr Ser Gln Pro Leu Met Thr Thr Pro Gly Thr Leu Ser
                 635                 640                 645

 Ser Thr Ala Ser Leu Val Thr Gly Pro Ile Ala Val Gln Thr Thr
                 650                 655                 660

 Ala Gly Lys Thr Ala Leu Ala Asp Pro Ser Glu Ile Leu Val Pro
                 665                 670                 675

 Gln Ile Ser Thr Glu Gly Gly Ile Ser Thr Glu Arg Asn Arg Val
                 680                 685                 690

 Ile Val Asp Ala Thr Thr Gly Leu Ile Pro Leu Thr Ser Val Pro
                 695                 700                 705

 Thr Ser Ala Lys Glu Met Thr Thr Lys Leu Gly Val Thr Ala Glu
                 710                 715                 720

 Tyr Ser Pro Ala Ser Arg Ser Leu Gly Thr Ser Pro Ser Pro Gln
                 725                 730                 735

 Thr Thr Val Val Ser Thr Ala Glu Asp Leu Ala Pro Lys Ser Ala
                 740                 745                 750

 Thr Phe Ala Val Gln Ser Ser Thr Gln Ser Pro Thr Thr Leu Ser
                 755                 760                 765

 Ser Ser Ala Ser Val Asn Ser Cys Ala Val Asn Pro Cys Leu His
                 770                 775                 780

 Asn Gly Glu Cys Val Ala Asp Asn Thr Ser Arg Gly Tyr His Cys
                 785                 790                 795

 Arg Cys Pro Pro Ser Trp Gln Gly Asp Asp Cys Ser Val Asp Val
                 800                 805                 810

 Asn Glu Cys Leu Ser Asn Pro Cys Pro Ser Thr Ala Thr Cys Asn
                 815                 820                 825

 Asn Thr Gln Gly Ser Phe Ile Cys Lys Cys Pro Val Gly Tyr Gln
                 830                 835                 840

 Leu Glu Lys Gly Ile Cys Asn Leu Val Arg Thr Phe Val Thr Glu
                 845                 850                 855

 Phe Lys Leu Lys Arg Thr Phe Leu Asn Thr Thr Val Glu Lys His
                 860                 865                 870

 Ser Asp Leu Gln Glu Val Glu Asn Glu Ile Thr Lys Thr Leu Asn
                 875                 880                 885

 Met Cys Phe Ser Ala Leu Pro Ser Tyr Ile Arg Ser Thr Val His
                 890                 895                 900

 Ala Ser Arg Glu Ser Asn Ala Val Val Ile Ser Leu Gln Thr Thr
                 905                 910                 915

 Phe Ser Leu Ala Ser Asn Val Thr Leu Phe Asp Leu Ala Asp Arg
                 920                 925                 930

 Met Gln Lys Cys Val Asn Ser Cys Lys Ser Ser Ala Glu Val Cys
                 935                 940                 945

 Gln Leu Leu Gly Ser Gln Arg Arg Ile Phe Arg Ala Gly Ser Leu
                 950                 955                 960

 Cys Lys Arg Lys Ser Pro Glu Cys Asp Lys Asp Thr Ser Ile Cys
                 965                 970                 975

 Thr Asp Leu Asp Gly Val Ala Leu Cys Gln Cys Lys Ser Gly Tyr
                 980                 985                 990

 Phe Gln Phe Asn Lys Met Asp His Ser Cys Arg Ala Cys Glu Asp
                 995                1000                1005

 Gly Tyr Arg Leu Glu Asn Glu Thr Cys Met Ser Cys Pro Phe Gly
                1010                1015                1020

 Leu Gly Gly Leu Asn Cys Gly Asn Pro Tyr Gln Leu Ile Thr Val
                1025                1030                1035

 Val Ile Ala Ala Ala Gly Gly Gly Leu Leu Leu Ile Leu Gly Ile
                1040                1045                1050

 Ala Leu Ile Val Thr Cys Cys Arg Lys Asn Lys Asn Asp Ile Ser
                1055                1060                1065

 Lys Leu Ile Phe Lys Ser Gly Asp Phe Gln Met Ser Pro Tyr Ala
                1070                1075                1080

 Glu Tyr Pro Lys Asn Pro Arg Ser Gln Glu Trp Gly Arg Glu Ala
                1085                1090                1095

 Ile Glu Met His Glu Asn Gly Ser Thr Lys Asn Leu Leu Gln Met
                1100                1105                1110

 Thr Asp Val Tyr Tyr Ser Pro Thr Ser Val Arg Asn Pro Glu Leu
                1115                1120                1125

 Glu Arg Asn Gly Leu Tyr Pro Ala Tyr Thr Gly Leu Pro Gly Ser
                1130                1135                1140

 Arg His Ser Cys Ile Phe Pro Gly Gln Tyr Asn Pro Ser Phe Ile
                1145                1150                1155

 Ser Asp Glu Ser Arg Arg Arg Asp Tyr Phe
                1160                1165

<210> 2723
<211> 1339
<212> DNA
<213> Homo sapien

<400> 2723
 ctaaacaaaa tcattcactt ccctgatttt gataagaaaa ttcctgtaaa 50

 gctgtttcct ctgcctctcc tctacgttgg aaaccacata agtggattat 100

 caagcacaag taaattaagc ctaccgatgt tcaccgtgct caggaaattc 150

 accattccac ttaccttact tctggaaacc atcatacttg ggaagcagta 200

 ttcactcaac atcatcctca gtgtctttgc cattattctc ggggctttca 250

 tagcagctgg gtctgacctt gcttttaact tagaaggcta tatttttgta 300

 ttcctgaatg atatcttcac atcagcaaat ggagtttata ccaaacagaa 350

 aatggaccca aaggagctag ggaaatacgg agtacttttc tacaatgcct 400

 gcttcatgat tatcccaact cttattatta gtgtctccac tggagacctc 450

 caacaggcta ctgaattcaa ccaatggaag aatgttgtgt ttatcctaca 500

 gtttcttctt tcctgttttt tggggtttct gctgatgtac tccacggttc 550

 tgtgcagcta ttacaattca gccctgacga cagcagtggt tggagccatc 600

 aagaatgtat ccgttgccta cattgggata ttaatcggtg gagactacat 650

 tttctctttg ttaaactttg tagggttaaa tatttgcatg gcagggggct 700

 tgagatattc ctttttaaca ctgagcagcc agttaaaacc taaacctgtg 750

 ggtgaagaaa acatctgttt ggatttgaag agctaaagag tctgcagcag 800

 gattggagac tgacttgtga ctgcgggctg ggggggcatt cccagtagga 850

 atgtgaagcc agaggtttcg gattcgtgac atccaccccc tgggcaagtg 900

 agagcatctg caaaatgcaa agagaactac ctcatatgca ggatgagcca 950

 atggcagtct caagaaatgt actcgggcga caccttacct gtggaaagca 1000

 aatcttttca aaataagcca ctgggactcg gtaggtggag ccccagctgc 1050

 tcttctaggg acctatgggg ccttcgtggc atctctgtgc tgtgtgctgg 1100

 ggaggaggtt gatgtaatgg tgactctttt ctgatcagca ccttggccgt 1150

 gattcccaag gtcccagcca aagcaaaggg ccagttgttt cagtttaaac 1200

 agacatgtct ttagtctaat aaaattagtt aactgccagt aaagttattt 1250

 gttagctttg atgaaagcta tgttggtatc tttccctaat catcaaagta 1300

 aataaaaaat catttctatg taaaaaaaaa aaaaaaaaa 1339

<210> 2724
<211> 261
<212> PRT
<213> Homo sapien

<400> 2724
 Leu Asn Lys Ile Ile His Phe Pro Asp Phe Asp Lys Lys Ile Pro
   1               5                  10                  15

 Val Lys Leu Phe Pro Leu Pro Leu Leu Tyr Val Gly Asn His Ile
                  20                  25                  30

 Ser Gly Leu Ser Ser Thr Ser Lys Leu Ser Leu Pro Met Phe Thr
                  35                  40                  45

 Val Leu Arg Lys Phe Thr Ile Pro Leu Thr Leu Leu Leu Glu Thr
                  50                  55                  60

 Ile Ile Leu Gly Lys Gln Tyr Ser Leu Asn Ile Ile Leu Ser Val
                  65                  70                  75

 Phe Ala Ile Ile Leu Gly Ala Phe Ile Ala Ala Gly Ser Asp Leu
                  80                  85                  90

 Ala Phe Asn Leu Glu Gly Tyr Ile Phe Val Phe Leu Asn Asp Ile
                  95                 100                 105

 Phe Thr Ser Ala Asn Gly Val Tyr Thr Lys Gln Lys Met Asp Pro
                 110                 115                 120

 Lys Glu Leu Gly Lys Tyr Gly Val Leu Phe Tyr Asn Ala Cys Phe
                 125                 130                 135

 Met Ile Ile Pro Thr Leu Ile Ile Ser Val Ser Thr Gly Asp Leu
                 140                 145                 150

 Gln Gln Ala Thr Glu Phe Asn Gln Trp Lys Asn Val Val Phe Ile
                 155                 160                 165

 Leu Gln Phe Leu Leu Ser Cys Phe Leu Gly Phe Leu Leu Met Tyr
                 170                 175                 180

 Ser Thr Val Leu Cys Ser Tyr Tyr Asn Ser Ala Leu Thr Thr Ala
                 185                 190                 195

 Val Val Gly Ala Ile Lys Asn Val Ser Val Ala Tyr Ile Gly Ile
                 200                 205                 210

 Leu Ile Gly Gly Asp Tyr Ile Phe Ser Leu Leu Asn Phe Val Gly
                 215                 220                 225

 Leu Asn Ile Cys Met Ala Gly Gly Leu Arg Tyr Ser Phe Leu Thr
                 230                 235                 240

 Leu Ser Ser Gln Leu Lys Pro Lys Pro Val Gly Glu Glu Asn Ile
                 245                 250                 255

 Cys Leu Asp Leu Lys Ser
                 260

<210> 2725
<211> 546
<212> DNA
<213> Homo sapien

<400> 2725
 attggagacc cttttcacaa gatggcgccg aaagcgaaga aggaagctcc 50

 tgcccctcct aaagctgaag ccaaagcgaa ggctttaaag gccaagaagg 100

 cagtgttgaa aggtgtccac agccacaaaa agaagaagat ccgcacgtca 150

 cccaccttcc ggcggccgaa gacactgcga ctccggagac agcccaaata 200

 tcctcggaag agcgctccca ggagaaacaa gcttgaccac tatgctatca 250

 tcaagtttcc gctgaccact gagtctgcca tgaagaagat agaagacaac 300

 aacacacttg tgttcattgt ggatgttaaa gccaacaagc accagattaa 350

 acaggctgtg aagaagctgt atgacattga tgtggccaag gtcaacaccc 400

 tgattcggcc tgatggagag aagaaggcat atgttcgact ggctcctgat 450

 tacgatgctt tggatgttgc caacaaaatt gggatcatct aaactgagtc 500

 cagctgccta attctgaata tatatatata tatatctttt caccat 546

<210> 2726
<211> 156
<212> PRT
<213> Homo sapien

<400> 2726
 Met Ala Pro Lys Ala Lys Lys Glu Ala Pro Ala Pro Pro Lys Ala
   1               5                  10                  15

 Glu Ala Lys Ala Lys Ala Leu Lys Ala Lys Lys Ala Val Leu Lys
                  20                  25                  30

 Gly Val His Ser His Lys Lys Lys Lys Ile Arg Thr Ser Pro Thr
                  35                  40                  45

 Phe Arg Arg Pro Lys Thr Leu Arg Leu Arg Arg Gln Pro Lys Tyr
                  50                  55                  60

 Pro Arg Lys Ser Ala Pro Arg Arg Asn Lys Leu Asp His Tyr Ala
                  65                  70                  75

 Ile Ile Lys Phe Pro Leu Thr Thr Glu Ser Ala Met Lys Lys Ile
                  80                  85                  90

 Glu Asp Asn Asn Thr Leu Val Phe Ile Val Asp Val Lys Ala Asn
                  95                 100                 105

 Lys His Gln Ile Lys Gln Ala Val Lys Lys Leu Tyr Asp Ile Asp
                 110                 115                 120

 Val Ala Lys Val Asn Thr Leu Ile Arg Pro Asp Gly Glu Lys Lys
                 125                 130                 135

 Ala Tyr Val Arg Leu Ala Pro Asp Tyr Asp Ala Leu Asp Val Ala
                 140                 145                 150

 Asn Lys Ile Gly Ile Ile
                 155

<210> 2727
<211> 5183
<212> DNA
<213> Homo sapien

<400> 2727
 ggaataacaa aacatgctct taaccatcat ccccctccag agaagctgga 50

 ggaaatttcc cccaccagtg acagtcatga gaaagacaca agttcccaaa 100

 gcaagtctga catcacaaga gaatcatctt ttacatcagc cgacactggg 150

 aattcactgt ctgcttttcc aagttataca ggcgcaggga tatctactga 200

 aggaagctcg gacttctcct ggggatatgg tgaactcgat caaaatgcca 250

 ctgaaaaagt ccagacaatg ttcacagcca ttgatgaact cttgtatgag 300

 cagaagttga gtgtgcatac caagagtcta caagaagagt gccaacagtg 350

 gacagctagc tttcctcacc tcaggattct aggtaggcag ataatcactc 400

 caagtgaagg ttatagattg tatcctagat ccccttctgc tgtttccgct 450

 tcatatgaaa caaccttgtc tcaagaaaga gattctacta tatttggtat 500

 aaggggaaag aagttacatt tttcatcttc ttatgctcat aaagcatctt 550

 ccattgccaa atcctccagc ttttgttcta tggaaagaga tgaggaagac 600

 tctataatcg tctcagaagg aataattgag gaatacctag cattcgatca 650

 catagatata gaagagggat ttcatgggaa gaaatcagaa gcagctacag 700

 agaaacagaa attagggtat cctcccattg ctccatttta ctgcatgaaa 750

 gaagatgtcc ttgcttatgt gtttgacagt gtatggtgca aggttgtgag 800

 ctgtatggag cagttgacac gtagtcactg ggaaggattt gcctctgatg 850

 atgagagtaa tgttgcagtt accagacccg attcagaaag ttcctgtgtg 900

 ctgagtgaac tacatccttt ggtgttaccg cgagtgccac agtctaaggt 950

 gctgtacatt acctcaaatc cgatgagtct ctgtcaagca agcagacatc 1000

 agccaaatgt gaatgatctc ttggttcatg gaatgcctct acagccaaga 1050

 aatctctccc taatggacaa gctcctagat cttgatgaca agctacttat 1100

 gaggcctggg tccagtacca tcctttcaac tcgaaattgg ccaaatcgag 1150

 ctgtggagtt tagtacatca tctctgtcat acacagtgca gtccaccagg 1200

 agacgcaatc caccaccacg aactcttcat ccgatcagca cgagccattc 1250

 atgtgctgaa acaccaagat ctgtggaaga aatcctcaga ggagcccgag 1300

 tcccagtggc acccgactcg ctctcctctc cctcaccgac gcccctgagt 1350

 cgaaataatc tgctaccacc tattggcaca gctgaagtgg aacatgtgag 1400

 cactgtgggg ccacaaagac agatgaaacc ccatggcgac tctagtcgag 1450

 ctcaaagtgc ggtggtggat gaacctaact atcagcagcc acaagaaagg 1500

 ctccttttgc ccgacttttt ccccaggccc aacacaactc aatcattttt 1550

 gctggataca cagtatcgtc gctcatgtgc agttgagtat cctcatcagg 1600

 cccgacctgg caggggatct gcaggtcctc agttacatgg gtctacaaaa 1650

 tctcaaagcg gaggcagacc agtctctcga accaggcagg gaccataagg 1700

 caaatgagaa gaatctatca ggctgcagga aacacgagat ttcatgaagc 1750

 agtattcagt catcaagtga tgcagagctt gtatagaaga tcgactagaa 1800

 atcatcttca tgaagagtga ttttggcaca agtgaccgaa gaacaaaaca 1850

 ccatagcagc caaaaatgac atgagtgttg tttctatctc cagttactgt 1900

 ctctttcagc agaaattaac ctatcccatt ggaaaggcaa gtttgtaccc 1950

 aaagatgcaa cagtgaataa tacccaaatc actgctcatg ttatctctta 2000

 acaatgatca gttcaatcat ataggatttg atgagctcac acatacacaa 2050

 aaagcagcaa atcatcagtg acaatatcac tggcttcaga atacttcagc 2100

 ctgtgttcat ttctggagag ttgtactcag ttttaagtca ttttgctgtt 2150

 gaaaatctga cctcatcaaa tagatgtcat tcctaaaact ctctttagat 2200

 gtcctaccct atcagcagat taaaatggaa ggggtgtgta actaaaaaca 2250

 taaatgttaa gcattagtat aaagtaactt ctgtaataaa ttatatcgca 2300

 tattttttca gataggacag ctcaacctta cgatgcctac ctgatgccag 2350

 gtgatgctta ttttcttcct aaagtaggtt actggtcata tcttttttcc 2400

 aaatattaaa tgcaccttgc cagatattct cctgcagctc taaggaaagg 2450

 aaatcaattt aaaaataatt tgtagaatct actattgagc caccaaagta 2500

 taattcccta aaagtttaag aaaccctggc aattaattca gcataaacat 2550

 atcctataaa cagcaggaga ggttcagctt tctgatttta ctgtggacct 2600

 tttcctaagg gcattcatga atgcagcaac agttttaact atggcttaca 2650

 tttattttaa atttcactaa atacaaatct tgattgtcat gccagtttta 2700

 gatcttatta attttcagaa tggataaatt caaataatca taaattacgg 2750

 taacttttta ttataccaag gtgttctaat gccatcatat gaagacagat 2800

 gcttcaaaca acctgcatta aattatattt ttaataaaat taaaatctat 2850

 ttttaaccta tttgtagtca caaaccgaaa acgtgtcgtc tttaccttag 2900

 agctaaaggc ttactttatg catacggtat atttaatagt ctacaaatca 2950

 aagatttaaa cagtccctta aaaattccat atattttcat accaactcat 3000

 ctacatagaa atgaaaatct ctattgttct cacaaaccat taccatgagt 3050

 tcactataac aactggatca atatggcttg cctttcaaag ttaaagaatc 3100

 agaaaggggc ctgtaagaag tcatttagcc caattccctc accctgtgtg 3150

 ttttccctca aagccagtgc aatttttttt taaccaaaaa actggacatg 3200

 tttaatacat acagtttgac aaatttggat ttcactcttt gttttgatgt 3250

 agtaactctt ttataaaagg gaacagattc agacaagctc agtggcccaa 3300

 ctgaagacat tcagcaatta atggcaggac ttcagtaatc agtggcagga 3350

 ctacaacata catctcttca tgctagggaa accaggctct ctattataaa 3400

 gctgaccagg gctattgttt tccccttttc tctcatccta aacaccattc 3450

 atatttttcc taggtcacat tttagtggga tcatttacaa agcccccaga 3500

 acttaatcat catgttttac cttttttatt gaattatata cacctcttac 3550

 aaaaatgctt gaagtaattt aacacctgta catcagtaca aaacctggct 3600

 gagtaaaatg aagagaggat ctattcaaga tcattaagac caaatgtaaa 3650

 ctgggaagta tgtggaagat agctgtccag caagtgtctg gaaggtgttc 3700

 tagctgggta gagagcctat tctaacagac acgcacatcg cagaaagcag 3750

 catgaacaga accacatcct agataagagt tctgtgtaca gaagatccat 3800

 ggaggcaagt gctgtcagga aggacactgc ctccctccac cctcccaaat 3850

 gtcaccacca agttccttca ggtgagacct cacacaatgt caagtgcttt 3900

 ctaggaaata ctaagatcag gttgagagat tctgcttggt ctagtcaatc 3950

 tgaaaaattc aggctggaaa gacacctttt ctcaagagct gaattgactt 4000

 ttgccttcaa atcctgcctg caccttgcct acgatggcat caatttacac 4050

 ctaaggacct ttgaagagaa aaattccatt atttcttttc tttcttgaga 4100

 gcagattttt tccctcctcc tttggaagat ttgcagtact ttgcttccat 4150

 ctgagccaga aaattgtcca tttccttttg ccgatccttt tgtctgctct 4200

 gtttgagaag ttaaaacaca agctttcaca acattatcca tagacagaaa 4250

 gtacctagtg gttgccaggg gctggaaaag tggaataact actaatgggt 4300

 atggagtttt tttggaatgg tgaaaatgtc ctacaattgg tgttaataat 4350

 tgtaaaactt tgtaaataca cttaaaacca ccaaattgta cactttaaaa 4400

 ggacaaatag aaggtatgcg gttatgtctt aaaagaagaa aacaaaatac 4450

 aacattccaa agaaaatatt agcagtagga atcagatcat taaagatgtg 4500

 gcaacaaact gccaagttta cctgaatggc tgccttcagg ctatccacgc 4550

 cttcatcaag ccccaactcc tttctgctca tttctgcttc tttggcctct 4600

 tcctgagcct gaaacaggaa ctcacatgag actcagggcc accaggaaat 4650

 gcttaaaata catactcttt cccaaaagca aatctataat tctgtttcaa 4700

 ttttatgaat atatgaatag acaaaatgaa tcgaattaca taactatgtc 4750

 attcattaaa tggcaacaat gctgacagca agcagtagat cctctgattc 4800

 caattaccat ttgtttttta cccaattcta tttgctagag gtagtaagta 4850

 ctctggcact cataaatcac atgatgataa aaaggaacat gaggccgggt 4900

 atggtggctc acaactgtaa tccccatacc ttgggaggcc aaggtgggag 4950

 gatcacttga actcaggagt tcaagacctg cctgggtaac atagtgagac 5000

 ctcagttcta taaaaaagaa aagaaatgag cctggtgtgg tggcatgtgc 5050

 ttgtagtccc agctactagg gaggctgagg tgggaagatg gcttcagtct 5100

 gagagttcag gctgcaataa gctgtgatca tgcctctgca ctccagcctg 5150

 ggtgatggag atgccatctc ttagaaaaaa gag 5183

<210> 2728
<211> 565
<212> PRT
<213> Homo sapien

<400> 2728
 Gly Ile Thr Lys His Ala Leu Asn His His Pro Pro Pro Glu Lys
   1               5                  10                  15

 Leu Glu Glu Ile Ser Pro Thr Ser Asp Ser His Glu Lys Asp Thr
                  20                  25                  30

 Ser Ser Gln Ser Lys Ser Asp Ile Thr Arg Glu Ser Ser Phe Thr
                  35                  40                  45

 Ser Ala Asp Thr Gly Asn Ser Leu Ser Ala Phe Pro Ser Tyr Thr
                  50                  55                  60

 Gly Ala Gly Ile Ser Thr Glu Gly Ser Ser Asp Phe Ser Trp Gly
                  65                  70                  75

 Tyr Gly Glu Leu Asp Gln Asn Ala Thr Glu Lys Val Gln Thr Met
                  80                  85                  90

 Phe Thr Ala Ile Asp Glu Leu Leu Tyr Glu Gln Lys Leu Ser Val
                  95                 100                 105

 His Thr Lys Ser Leu Gln Glu Glu Cys Gln Gln Trp Thr Ala Ser
                 110                 115                 120

 Phe Pro His Leu Arg Ile Leu Gly Arg Gln Ile Ile Thr Pro Ser
                 125                 130                 135

 Glu Gly Tyr Arg Leu Tyr Pro Arg Ser Pro Ser Ala Val Ser Ala
                 140                 145                 150

 Ser Tyr Glu Thr Thr Leu Ser Gln Glu Arg Asp Ser Thr Ile Phe
                 155                 160                 165

 Gly Ile Arg Gly Lys Lys Leu His Phe Ser Ser Ser Tyr Ala His
                 170                 175                 180

 Lys Ala Ser Ser Ile Ala Lys Ser Ser Ser Phe Cys Ser Met Glu
                 185                 190                 195

 Arg Asp Glu Glu Asp Ser Ile Ile Val Ser Glu Gly Ile Ile Glu
                 200                 205                 210

 Glu Tyr Leu Ala Phe Asp His Ile Asp Ile Glu Glu Gly Phe His
                 215                 220                 225

 Gly Lys Lys Ser Glu Ala Ala Thr Glu Lys Gln Lys Leu Gly Tyr
                 230                 235                 240

 Pro Pro Ile Ala Pro Phe Tyr Cys Met Lys Glu Asp Val Leu Ala
                 245                 250                 255

 Tyr Val Phe Asp Ser Val Trp Cys Lys Val Val Ser Cys Met Glu
                 260                 265                 270

 Gln Leu Thr Arg Ser His Trp Glu Gly Phe Ala Ser Asp Asp Glu
                 275                 280                 285

 Ser Asn Val Ala Val Thr Arg Pro Asp Ser Glu Ser Ser Cys Val
                 290                 295                 300

 Leu Ser Glu Leu His Pro Leu Val Leu Pro Arg Val Pro Gln Ser
                 305                 310                 315

 Lys Val Leu Tyr Ile Thr Ser Asn Pro Met Ser Leu Cys Gln Ala
                 320                 325                 330

 Ser Arg His Gln Pro Asn Val Asn Asp Leu Leu Val His Gly Met
                 335                 340                 345

 Pro Leu Gln Pro Arg Asn Leu Ser Leu Met Asp Lys Leu Leu Asp
                 350                 355                 360

 Leu Asp Asp Lys Leu Leu Met Arg Pro Gly Ser Ser Thr Ile Leu
                 365                 370                 375

 Ser Thr Arg Asn Trp Pro Asn Arg Ala Val Glu Phe Ser Thr Ser
                 380                 385                 390

 Ser Leu Ser Tyr Thr Val Gln Ser Thr Arg Arg Arg Asn Pro Pro
                 395                 400                 405

 Pro Arg Thr Leu His Pro Ile Ser Thr Ser His Ser Cys Ala Glu
                 410                 415                 420

 Thr Pro Arg Ser Val Glu Glu Ile Leu Arg Gly Ala Arg Val Pro
                 425                 430                 435

 Val Ala Pro Asp Ser Leu Ser Ser Pro Ser Pro Thr Pro Leu Ser
                 440                 445                 450

 Arg Asn Asn Leu Leu Pro Pro Ile Gly Thr Ala Glu Val Glu His
                 455                 460                 465

 Val Ser Thr Val Gly Pro Gln Arg Gln Met Lys Pro His Gly Asp
                 470                 475                 480

 Ser Ser Arg Ala Gln Ser Ala Val Val Asp Glu Pro Asn Tyr Gln
                 485                 490                 495

 Gln Pro Gln Glu Arg Leu Leu Leu Pro Asp Phe Phe Pro Arg Pro
                 500                 505                 510

 Asn Thr Thr Gln Ser Phe Leu Leu Asp Thr Gln Tyr Arg Arg Ser
                 515                 520                 525

 Cys Ala Val Glu Tyr Pro His Gln Ala Arg Pro Gly Arg Gly Ser
                 530                 535                 540

 Ala Gly Pro Gln Leu His Gly Ser Thr Lys Ser Gln Ser Gly Gly
                 545                 550                 555

 Arg Pro Val Ser Arg Thr Arg Gln Gly Pro
                 560                 565

<210> 2729
<211> 2446
<212> DNA
<213> Homo sapien

<400> 2729
 attcacgagt cctgcatgag ccagataggc tggaaccgca tcatcgtgga 50

 gaagcccttc gggagggacc tgcagagctc tgaccggctg tccaaccaca 100

 tctcctccct gttccgtgag gaccagatct accgcatcga ccactacctg 150

 ggcaaggaga tggtgcagaa cctcatggtg ctgagatttg ccaacaggat 200

 cttcggcccc atctggaacc gggacaacat cgcctgcgtt atcctcacct 250

 tcaaggagcc ctttggcact gagggtcgcg ggggctattt cgatgaattt 300

 gggatcatcc gggacgtgat gcagaaccac ctactgcaga tgctgtgtct 350

 ggtggccatg gagaagcccg cctccaccaa ctcagatgac gtccgtgatg 400

 agaaggtcaa ggtgttgaaa tgcatctcag aggtgcaggc caacaatgtg 450

 gtcctgggcc agtacgtggg gaaccccgat ggagagggcg aggccaccaa 500

 agggtacctg gacgacccca cggtgccccg cgggtccacc accgccactt 550

 ttgcagccgt cgtcctctat gtggagaatg agaggtggga tggggtgccc 600

 ttcatcctgc gctgcggcaa ggccctgaac gagcgcaagg ccgaggtgag 650

 gctgcagttc catgatgtgg ccggcgacat cttccaccag cagtgcaagc 700

 gcaacgagct ggtgatccgc gtgcagccca acgaggccgt gtacaccaag 750

 atgatgacca agaagccggg catgttcttc aaccccgagg agtcggagct 800

 ggacctgacc tacggcaaca gatacaagaa cgtgaagctc cctgagccct 850

 acgagcgcct catcctggac gtcttctgcg ggagccagat gcacttcgtg 900

 cgcagcgacg agctccgtga ggcctggcgt attttcaccc cactgctgca 950

 ccagattgag ctggagaagc ccaagcccat cccctatatt tatggcagcc 1000

 gaggccccac ggaggcagac gagctgatga agagagtggg tttccagtat 1050

 gagggcacct acaagtgggt gaacccccac aagctctgag ccctgggcac 1100

 ccacctccac ccccgccacg gccaccctcc ttcccgccgc cgacccgagt 1150

 cgggaggact ccgggaccat tgacctcagc tgcacattcc tggccccggg 1200

 ctctggcacc ctggccgccc ctcgctgctg ctactacccg agcccagcta 1250

 cattcctcag ctgccaagca ctcgagacca tcctggcccc tccagaccct 1300

 gcctgagccc aggagctgag tcacctcctc cactcactcc agcccaacag 1350

 aaggaaggag gagggcgccc attcgtctgt cccagagctt attggccact 1400

 gggtctcact cctgagtggg gccagggtgg gagggaggga caagggggag 1450

 gaaaggggcg agcacccacg tgagagaatc tgctgtgcct tgcccgccag 1500

 cctcagtgcc acttgacatt ccttgtcacc agcaacatct cgagccccct 1550

 ggatgtcccc tgtcccacca actctgcact ccatggccac cccgtgccac 1600

 ccgtaggcag cctctctgct ataagaaaag cagacgcagc agctgggacc 1650

 cctcccaacc tcaatgccct gtaaggattt tgcccactgg gcaactcaga 1700

 aatacttcga tctcccaaga tataagaggc agcagcaaac gtgcctattg 1750

 acgtctgttt catagttacc acttacgcga gtagacagaa ctcggctttt 1800

 cagaaaatag gtgtcaagtc cactttataa gaaccttttt ttctaaaata 1850

 agataaaagg tggctttgca ttttctgatt aaacgactgt gtctttgtca 1900

 cctctgctta actttaggag tatccattcc tgtgattgta gacttttgtt 1950

 gatattcttc ctggaagaat atcattcttt tcttgaaggg ttggtttact 2000

 agaatattca aaatcaatca tgaaggcagt tactattttg agtctaaagg 2050

 ttttctaaaa attaacctca catcccttct gttagggtct ttcagaatat 2100

 cttttataaa cagaagcatt tgaagtcatt gcttttgcta catgatttgt 2150

 gtgtgtgaag gacataccac gtttaaatca ttaattgaaa aacatcatat 2200

 aagccccaac tttgtttgga ggaagagacg gaggttgagg tttttccttc 2250

 tgtataagca cctactgaca aaatgtagag gccattcaac cgtcaaacac 2300

 catttggtta tatcgcagag gagacggatg tgtaaattac tgcattgctt 2350

 tttttttcag tttgtataac ctctaatctc cgtttgcatg atacgctttg 2400

 ttagaaacat taattgtagt ttggaagcaa gtgtgtatgg gaattc 2446

<210> 2730
<211> 5182
<212> DNA
<213> Homo sapien

<400> 2730
 accttcagtt cctccaagtc ctggaagact gagacaaggg gaagaaagca 50

 agataagtgc gatggatgca tctccacgga atatttctcc aggacttcag 100

 aatggagaaa aagaggatcg cttcttaaca actttgtcca gccagagctc 150

 caccagttct actcatctcc aattgcctac gccacctgaa gtcatgtctg 200

 aacagtcagt gggagggccc cctgagctag atacagccag cagttccgaa 250

 gatgtgtttg atgggcattt gctgggatcc acagacagcc aagtgaagga 300

 aaagtcaacc atgaaagcca tctttgcaaa tttgcttcca ggaaatagct 350

 ataatcctat tccatttcct tttgatccag ataaacacta cttaatgtat 400

 gaacatgaac gagtgcccat tgcagtctgc gagaaggaac ccagctccat 450

 cattgctttt gctctcagtt gtaaagaata ccgaaatgcc ttagaggaat 500

 tgtctaaagc gactcagtgg aacagtgccg aagaagggct tccaacaaat 550

 agtacttcag atagcagacc aaagagtagc agccctatca gattacctga 600

 aatgagtgga ggacagacaa atcgtacaac agaaacagaa ccacaaccaa 650

 ccaaaaaggc ttctggaatg ttgtccttct tcagagggac agcagggaaa 700

 agccccgatc tctcttccca gaagagagag accttacgtg gagcagatag 750

 tgcttactac caggttgggc agacaggcaa ggaggggacc gagaatcaag 800

 gcgttgagcc tcaagatgaa gtagatggag gagatacgca aaagaagcaa 850

 ctcataaatc ctcatgtgga acttcaattt tcagatgcta atgccaagtt 900

 ttactgtcgg ctctactatg cgggagagtt tcataagatg cgtgaagtga 950

 ttctggacag cagtgaggaa gatttcattc gttccctctc ccactcatca 1000

 ccctggcagg cccggggagg caaatcagga gctgccttct atgcaactga 1050

 ggatgataga tttattttga agcaaatgcc tcgtctggaa gtccagtcct 1100

 tcctcgactt tgcaccacat tacttcaatt atattacaaa tgctgttcaa 1150

 caaaagaggc ccacggcgtt ggccaaaatt cttggagttt acagaattgg 1200

 ttataagaac tctcagaaca acactgagaa gaagttagat ctccttgtca 1250

 tggaaaatct tttctacggg agaaagatgg cacaggtttt tgatttgaag 1300

 ggctctctta ggaatcggaa tgtaaaaact gacactggaa aagagagttg 1350

 tgatgtggtc ctgctagatg aaaatctcct aaagatggtt cgagacaacc 1400

 ctctatatat tcgttctcat tccaaagctg tgctgagaac ctcgatccat 1450

 agtgactccc atttcctttc tagccacctc attatagatt attctttgct 1500

 ggttgggcga gatgatacta gcaatgagct agtagttgga attatagatt 1550

 atattcgaac atttacatgg gacaaaaagc ttgagatggt tgtgaaatca 1600

 acaggaattt taggtggaca aggtaaaatg ccaacagtgg tgtctccgga 1650

 gttgtacagg actaggtttt gtgaggcaat ggacaagtat ttcctaatgg 1700

 taccagacca ctggacaggc ttgggtctga attgctgaaa tcaagcacat 1750

 attttgaaat ggactgtgaa ggaaaagggg acaggaacaa aggaccaaaa 1800

 ataagctaca tgttttattt cttcatcgtg ttcaccactg tatgccaagg 1850

 cttttcagtt ctgtgtctgt ttagactgtc cgtaatggaa tggtaaaact 1900

 ccatgaattt gcactttggt ttttgatacc tgtggagctg tctgtacgtt 1950

 gggaagtggc atgaaaattt tcttaagcta aaatacagac atgtttcaaa 2000

 gggctaaagt tggagatgag tagatagggt gaaaaatggg ttaaatttgc 2050

 tagcttaatt gttttaagaa gaaaacagtg tctcataaat tgactatcct 2100

 ggcatcacat ttaacatgtt atctacttag aaagcatttg tagagctgct 2150

 gaatttgttt tgtgtttttc tgtaataatt taatgttact tattatcaga 2200

 atttctgaaa cctttacaaa aattctgatt tattccatta atggccagtt 2250

 aaacacgtgg gcatttattg ttttattgag gaatttgact taaactggga 2300

 atcctgtcat gttgtttatc tttccagctt gcctgttttt gagtatgttt 2350

 gatgttttta aaattttgtc ttctctgtgg atgacaggag gctacagcaa 2400

 ttaactttaa gcctcctttt agagatattt ttaaagcttg tttaaaattt 2450

 ttgtgcaatt catatattaa attgcactta cttgcatacg ctcatattct 2500

 agggtttttt ctctattttt agggtatcat agtaaatcat tagtaaatga 2550

 gtctgtagtt actaaaccct aatggaataa ttattaatga aagatttttg 2600

 aaatataaaa aataaattag gcccaatcca agaaattgag tgagaaggaa 2650

 acacttgttt tattcacaga ggtaaagtgt cttttcaata taaccagcaa 2700

 tttaggtggc atctataaaa taaaaaattt ctactgtgga catccccttt 2750

 tccaactttc tacataatgg ctagttctga ctactaagaa atgttaagaa 2800

 ataggccaag tgcggtggct cacgcctata atcctatcac tttgggaggc 2850

 ctaggcaggc agatcacctg aggtcaggag ttcaagacca gcctggccaa 2900

 catgaggaaa ccccatctct actaaaaaga caaaaaatta gctgggcatg 2950

 gtggcatata cctgtaaccc caactacttg ggtggctgag gcaggagaat 3000

 tgtttgaacc tgggaggcgg aggctgcagt gagctgggat tacaccattg 3050

 cattccagcc tgggcaacag agcaagactg tctcaaaaaa caaaacgaaa 3100

 caaaaaaaga aagttattct tagtaaggaa cttcttgttt aatagcattt 3150

 ttgtttattt taaaaagtga tcagaagtag taaactatct ttgaggaaat 3200

 actgtaaccc cagaatattt cctcttgact tctttttgta acaaggataa 3250

 tttagggatt tataaagttg taaggatttc actgttttcg gactgcctat 3300

 aataatagca cattaacctt cacataataa gaaatctgga caagttcagt 3350

 tacacagtat gatgaatact tgaattagga acattgtgga aaatttgctt 3400

 tagagaatca aggcagtagt ttggtatttg gtgcttatta aaaatgtggt 3450

 ttgttttgaa ctggaagcaa gttgaccaag gacttatgac taatgtgatg 3500

 ctaagttcca cttggcccct tttaaaaacg tgtatgtgcc ttttgaagat 3550

 acacaaaaca ctgaggattt tagttttgaa atcaaagact attaaaggag 3600

 ctgtacagag gtaaaaaaat aaatgtggaa cattattaac ttattttgtg 3650

 tctaggaaca atggattttg tatctgattt aaaatgccaa cactgttttg 3700

 tctctgttca ttttttctgt gaggatactt aaggttatta ttcctgtctg 3750

 tttcctgtac tcccctagtc atgagcactt gaagtacaag gtgtctcccc 3800

 ctaggtgcaa ttaggttgtt tctttgtttt tagtttcaat tctatgtgca 3850

 tagcaggaat gctccacagg aatggcttct gacaataatc tgtcctgttg 3900

 attttgtttt ccttgcccat gacttgaaca actgtgtttt aaagtactgt 3950

 agtctagtag gtaactttgt ggcaaaaatt ttcaatataa tacattctga 4000

 aacaatagtt gctgccttgc aaaggtaatc tctcatttta aaattggaca 4050

 gtattaatga aggggaaata tacaatttat ttctattgag tggtagaact 4100

 atatgtctgg tcccttgctg ctcttgttta ggccactatc atagatatat 4150

 ttcaaatatt gtactactca gtgttaagta ttgaatgact gtttcccttt 4200

 ccttcaaggc ctagagtata ttctgaaaat ttaggaatga ggaagaaatc 4250

 ttaatacttc cttccttaac atacaacatg agtcccgaga ataattgata 4300

 gtagcaagag aaaactatgt cagtaacatg ttgctttgta taaaaatctt 4350

 atttataaat gtgaagcttt ttgatgccat caaaacttat taaaaaatag 4400

 gatttacttt tttctaattc tgacctaaga aaaataatga gaacaagctg 4450

 ttgcaagctc ttttgtagtc tattgaatat tttatagata ttcaaaattt 4500

 cctacaaact ataatttttt ccatgattta gcagtgagtg attttctagc 4550

 tttggctctt attaggtatt gtaaatagta gggttatatc gatatcagct 4600

 tttgtgatgg cattgtggtc atcagcttca tgacatttta cccatttgca 4650

 gtgatcctgt gtaaaactgc caaggaaagt aattacctgt aggagtttgc 4700

 tgagcttgaa gagtgaaaac tgttgtgaat gagcctgatc ataaaacgga 4750

 ccaggccatt cattattcct caagtgttaa tatactgact tatgcagtat 4800

 tcaaaccatc tagtgcaatg tttttgtttt tgtttttttt ttttttggta 4850

 acacaggtgc agtgtattat agaaaaaata aaaactacaa tcattagcag 4900

 ttttaatact gctgtgtcag ttttgtaaaa aatgtacatt atgtcttttg 4950

 acatgttgaa ttttaaacta gggaaatgac attgtaaatc atagtagcct 5000

 cttttaattt aatatgaaaa atgccactat attgaaagta cttaatgtat 5050

 tgtatatatt tctctacttt ggttctagct attttatatg attgacatgt 5100

 tatttaaaag ataactgcct tgaacttttg gagacttgta ctgtaaataa 5150

 agaaatctta acaataaact cagaatctac tt 5182

<210> 2731
<211> 578
<212> PRT
<213> Homo sapien

<400> 2731
 Pro Ser Val Pro Pro Ser Pro Gly Arg Leu Arg Gln Gly Glu Glu
   1               5                  10                  15

 Ser Lys Ile Ser Ala Met Asp Ala Ser Pro Arg Asn Ile Ser Pro
                  20                  25                  30

 Gly Leu Gln Asn Gly Glu Lys Glu Asp Arg Phe Leu Thr Thr Leu
                  35                  40                  45

 Ser Ser Gln Ser Ser Thr Ser Ser Thr His Leu Gln Leu Pro Thr
                  50                  55                  60

 Pro Pro Glu Val Met Ser Glu Gln Ser Val Gly Gly Pro Pro Glu
                  65                  70                  75

 Leu Asp Thr Ala Ser Ser Ser Glu Asp Val Phe Asp Gly His Leu
                  80                  85                  90

 Leu Gly Ser Thr Asp Ser Gln Val Lys Glu Lys Ser Thr Met Lys
                  95                 100                 105

 Ala Ile Phe Ala Asn Leu Leu Pro Gly Asn Ser Tyr Asn Pro Ile
                 110                 115                 120

 Pro Phe Pro Phe Asp Pro Asp Lys His Tyr Leu Met Tyr Glu His
                 125                 130                 135

 Glu Arg Val Pro Ile Ala Val Cys Glu Lys Glu Pro Ser Ser Ile
                 140                 145                 150

 Ile Ala Phe Ala Leu Ser Cys Lys Glu Tyr Arg Asn Ala Leu Glu
                 155                 160                 165

 Glu Leu Ser Lys Ala Thr Gln Trp Asn Ser Ala Glu Glu Gly Leu
                 170                 175                 180

 Pro Thr Asn Ser Thr Ser Asp Ser Arg Pro Lys Ser Ser Ser Pro
                 185                 190                 195

 Ile Arg Leu Pro Glu Met Ser Gly Gly Gln Thr Asn Arg Thr Thr
                 200                 205                 210

 Glu Thr Glu Pro Gln Pro Thr Lys Lys Ala Ser Gly Met Leu Ser
                 215                 220                 225

 Phe Phe Arg Gly Thr Ala Gly Lys Ser Pro Asp Leu Ser Ser Gln
                 230                 235                 240

 Lys Arg Glu Thr Leu Arg Gly Ala Asp Ser Ala Tyr Tyr Gln Val
                 245                 250                 255

 Gly Gln Thr Gly Lys Glu Gly Thr Glu Asn Gln Gly Val Glu Pro
                 260                 265                 270

 Gln Asp Glu Val Asp Gly Gly Asp Thr Gln Lys Lys Gln Leu Ile
                 275                 280                 285

 Asn Pro His Val Glu Leu Gln Phe Ser Asp Ala Asn Ala Lys Phe
                 290                 295                 300

 Tyr Cys Arg Leu Tyr Tyr Ala Gly Glu Phe His Lys Met Arg Glu
                 305                 310                 315

 Val Ile Leu Asp Ser Ser Glu Glu Asp Phe Ile Arg Ser Leu Ser
                 320                 325                 330

 His Ser Ser Pro Trp Gln Ala Arg Gly Gly Lys Ser Gly Ala Ala
                 335                 340                 345

 Phe Tyr Ala Thr Glu Asp Asp Arg Phe Ile Leu Lys Gln Met Pro
                 350                 355                 360

 Arg Leu Glu Val Gln Ser Phe Leu Asp Phe Ala Pro His Tyr Phe
                 365                 370                 375

 Asn Tyr Ile Thr Asn Ala Val Gln Gln Lys Arg Pro Thr Ala Leu
                 380                 385                 390

 Ala Lys Ile Leu Gly Val Tyr Arg Ile Gly Tyr Lys Asn Ser Gln
                 395                 400                 405

 Asn Asn Thr Glu Lys Lys Leu Asp Leu Leu Val Met Glu Asn Leu
                 410                 415                 420

 Phe Tyr Gly Arg Lys Met Ala Gln Val Phe Asp Leu Lys Gly Ser
                 425                 430                 435

 Leu Arg Asn Arg Asn Val Lys Thr Asp Thr Gly Lys Glu Ser Cys
                 440                 445                 450

 Asp Val Val Leu Leu Asp Glu Asn Leu Leu Lys Met Val Arg Asp
                 455                 460                 465

 Asn Pro Leu Tyr Ile Arg Ser His Ser Lys Ala Val Leu Arg Thr
                 470                 475                 480

 Ser Ile His Ser Asp Ser His Phe Leu Ser Ser His Leu Ile Ile
                 485                 490                 495

 Asp Tyr Ser Leu Leu Val Gly Arg Asp Asp Thr Ser Asn Glu Leu
                 500                 505                 510

 Val Val Gly Ile Ile Asp Tyr Ile Arg Thr Phe Thr Trp Asp Lys
                 515                 520                 525

 Lys Leu Glu Met Val Val Lys Ser Thr Gly Ile Leu Gly Gly Gln
                 530                 535                 540

 Gly Lys Met Pro Thr Val Val Ser Pro Glu Leu Tyr Arg Thr Arg
                 545                 550                 555

 Phe Cys Glu Ala Met Asp Lys Tyr Phe Leu Met Val Pro Asp His
                 560                 565                 570

 Trp Thr Gly Leu Gly Leu Asn Cys
                 575

<210> 2732
<211> 2630
<212> DNA
<213> Homo sapien

<400> 2732
 cggacgcgtg ggcggacgcg tgggcggacg cgtgggctct gggagtgtga 50

 aactgggaga gacggttaag ctggggacgg tattcagaat tcgagcgcag 100

 gagctccgct tctccacctg ctcccgggga gctattggga tccagagaat 150

 cacccgctga tggtttttcc ccaggcctga aacaaccaga gagctacggg 200

 aaaggaaggg cttggcttgc cagaggaatt ttccaagtgc tcaaacgcca 250

 ggcttacggc gcctgtgatc cgtccaggag gacaaagtgg gatttgaaga 300

 tccactccac ttctgctcat ggcgggccag ggcctgcccc tgcacgtggc 350

 cacactgctg actgggctgc tggaatgcct gggctttgct ggcgtcctct 400

 ttggctggcc ttcactagtg tttgtcttca agaatgaaga ttactttaag 450

 gatctgtgtg gaccagatgc tgggccgatt ggcaatgcca cagggcaggc 500

 tgactgcaaa gcccaggatg agaggttctc actcatcttc accctggggt 550

 ccttcatgaa caacttcatg acattcccca ctggctacat ctttgaccgg 600

 ttcaagacca ccgtggcacg cctcatagcc atatttttct acaccaccgc 650

 cacactcatc atagccttca cctctgcagg ctcagccgtg ctgctcttcc 700

 tggccatgcc aatgctcacc attgggggaa tcctgtttct catcaccaac 750

 ctgcagattg ggaacctatt tggccaacac cgttcgacca tcatcactct 800

 gtacaatgga gcatttgact cttcctcggc agtcttcctt attattaagc 850

 ttctttatga aaaaggcatc agcctcaggg cctccttcat cttcatctct 900

 gtctgcagta cctggcatgt agcacgcact ttcctcctga tgccccgggg 950

 gcacatccca tacccactgc cccccaacta cagctatggc ctgtgccctg 1000

 ggaatggcac cacaaaggaa gagaaggaaa cagctgagca tgaaaacagg 1050

 gagctacagt caaaggagtt cctttcagcg aaggaagaga ccccaggggc 1100

 agggcagaag caggaactcc gctccttctg gagctacgct ttctctcggc 1150

 gctttgcctg gcacctggtg tggctgtctg tgatacagtt gtggcactac 1200

 ctcttcattg gcactctcaa ctccttgctg accaacatgg ccggtgggga 1250

 catggcacga gtcagcacct acacaaatgc ctttgccttc actcagttcg 1300

 gagtgctgtg tgccccctgg aatggcctgc tcatggaccg gcttaaacag 1350

 aagtaccaga aggaagcaag aaagacaggt tcctccactt tggcggtggc 1400

 cctctgctcg acggtgcctt cgctggccct gacatccctg ctgtgcctgg 1450

 gcttcgccct ctgtgcctca gtccccatcc tccctctcca gtacctcacc 1500

 ttcatcctgc aagtgatcag ccgctccttc ctctatggga gcaacgcggc 1550

 cttcctcacc cttgctttcc cttcagagca ctttggcaag ctctttgggc 1600

 tggtgatggc cttgtcggct gtggtgtctc tgctccagtt ccccatcttc 1650

 accctcatca aaggctccct tcagaatgac ccattttacg tgaatgtgat 1700

 gttcatgctt gccattcttc tgacattctt ccaccccttt ctggtatatc 1750

 gggaatgccg tacttggaaa gaaagtccct ctgcaattgc atagttcaga 1800

 agccctcact tttcagcccc gaggatggtt ttgttcatct tccaccacct 1850

 ttgaggacct cgtgtcccaa aagactttgc ctatcccagc aaaacacaca 1900

 cacacacaca cacacacaca aaataaagac acacaaggac gtctgcgcag 1950

 caagaaaaga atctcagttg ccaagcagat tgatatcaca cagactcaaa 2000

 gcaaaggcat gtggaacttc tttatttcaa aacagaagtg tctccttgca 2050

 cttagccttg gcagaccctt gactccaggg gagatgacct gggggaggaa 2100

 gtgtgtcaac tatttcttta ggcctgtttg gctccgaagc ctatatgtgc 2150

 ctggatcctc tgccacgggt taaattttca ggtgaagagt gaggttgtca 2200

 tggcctcagc tatgcttcct ggctctccct caagagtgca gccttggcta 2250

 gagaactcac agctctggga aaaagaggag cagacagggt tccctgggcc 2300

 cagtctcagc ccagccactg atgctggatg accttggcct gaccctggtc 2350

 tggtctcaga atcacttttc ccatctgtaa aattgagatg aattttggtg 2400

 ttgaaagttc ttcctggagc agatgtccta gaaggtttta ggaatagtga 2450

 cagagtcagg ccaccccaag ggccatggga gccagctgac ctgcttgacc 2500

 gaaggatttc tgacagacta tctttgggga tgttttcaag aagggatata 2550

 agttatttac tttgggcatt taaaagaaaa tttctctcgg gaataatttt 2600

 atagaaaaat aaagcttctg tgtctaaggc 2630

<210> 2733
<211> 491
<212> PRT
<213> Homo sapien

<400> 2733
 Met Ala Gly Gln Gly Leu Pro Leu His Val Ala Thr Leu Leu Thr
   1               5                  10                  15

 Gly Leu Leu Glu Cys Leu Gly Phe Ala Gly Val Leu Phe Gly Trp
                  20                  25                  30

 Pro Ser Leu Val Phe Val Phe Lys Asn Glu Asp Tyr Phe Lys Asp
                  35                  40                  45

 Leu Cys Gly Pro Asp Ala Gly Pro Ile Gly Asn Ala Thr Gly Gln
                  50                  55                  60

 Ala Asp Cys Lys Ala Gln Asp Glu Arg Phe Ser Leu Ile Phe Thr
                  65                  70                  75

 Leu Gly Ser Phe Met Asn Asn Phe Met Thr Phe Pro Thr Gly Tyr
                  80                  85                  90

 Ile Phe Asp Arg Phe Lys Thr Thr Val Ala Arg Leu Ile Ala Ile
                  95                 100                 105

 Phe Phe Tyr Thr Thr Ala Thr Leu Ile Ile Ala Phe Thr Ser Ala
                 110                 115                 120

 Gly Ser Ala Val Leu Leu Phe Leu Ala Met Pro Met Leu Thr Ile
                 125                 130                 135

 Gly Gly Ile Leu Phe Leu Ile Thr Asn Leu Gln Ile Gly Asn Leu
                 140                 145                 150

 Phe Gly Gln His Arg Ser Thr Ile Ile Thr Leu Tyr Asn Gly Ala
                 155                 160                 165

 Phe Asp Ser Ser Ser Ala Val Phe Leu Ile Ile Lys Leu Leu Tyr
                 170                 175                 180

 Glu Lys Gly Ile Ser Leu Arg Ala Ser Phe Ile Phe Ile Ser Val
                 185                 190                 195

 Cys Ser Thr Trp His Val Ala Arg Thr Phe Leu Leu Met Pro Arg
                 200                 205                 210

 Gly His Ile Pro Tyr Pro Leu Pro Pro Asn Tyr Ser Tyr Gly Leu
                 215                 220                 225

 Cys Pro Gly Asn Gly Thr Thr Lys Glu Glu Lys Glu Thr Ala Glu
                 230                 235                 240

 His Glu Asn Arg Glu Leu Gln Ser Lys Glu Phe Leu Ser Ala Lys
                 245                 250                 255

 Glu Glu Thr Pro Gly Ala Gly Gln Lys Gln Glu Leu Arg Ser Phe
                 260                 265                 270

 Trp Ser Tyr Ala Phe Ser Arg Arg Phe Ala Trp His Leu Val Trp
                 275                 280                 285

 Leu Ser Val Ile Gln Leu Trp His Tyr Leu Phe Ile Gly Thr Leu
                 290                 295                 300

 Asn Ser Leu Leu Thr Asn Met Ala Gly Gly Asp Met Ala Arg Val
                 305                 310                 315

 Ser Thr Tyr Thr Asn Ala Phe Ala Phe Thr Gln Phe Gly Val Leu
                 320                 325                 330

 Cys Ala Pro Trp Asn Gly Leu Leu Met Asp Arg Leu Lys Gln Lys
                 335                 340                 345

 Tyr Gln Lys Glu Ala Arg Lys Thr Gly Ser Ser Thr Leu Ala Val
                 350                 355                 360

 Ala Leu Cys Ser Thr Val Pro Ser Leu Ala Leu Thr Ser Leu Leu
                 365                 370                 375

 Cys Leu Gly Phe Ala Leu Cys Ala Ser Val Pro Ile Leu Pro Leu
                 380                 385                 390

 Gln Tyr Leu Thr Phe Ile Leu Gln Val Ile Ser Arg Ser Phe Leu
                 395                 400                 405

 Tyr Gly Ser Asn Ala Ala Phe Leu Thr Leu Ala Phe Pro Ser Glu
                 410                 415                 420

 His Phe Gly Lys Leu Phe Gly Leu Val Met Ala Leu Ser Ala Val
                 425                 430                 435

 Val Ser Leu Leu Gln Phe Pro Ile Phe Thr Leu Ile Lys Gly Ser
                 440                 445                 450

 Leu Gln Asn Asp Pro Phe Tyr Val Asn Val Met Phe Met Leu Ala
                 455                 460                 465

 Ile Leu Leu Thr Phe Phe His Pro Phe Leu Val Tyr Arg Glu Cys
                 470                 475                 480

 Arg Thr Trp Lys Glu Ser Pro Ser Ala Ile Ala
                 485                 490

<210> 2734
<211> 1086
<212> DNA
<213> Homo sapien

<400> 2734
 gggcgggccc gcacccctgc gaacatggcg ctgcgagtgg tgcggagcgt 50

 gcgggccctg ctctgcaccc tgcgcgcggt cccgttaccc gccgcgccct 100

 gcccgccgag gccctggcag ctgggggtgg gcgccgtccg tacgctgcgc 150

 actggacccg ctctgctctc ggtgcgtaaa ttcacagaga aacacgaatg 200

 ggtaacaaca gaaaatggca ttggaacagt gggaatcagc aattttgcac 250

 aggaagcgtt gggagatgtt gtttattgta gtctccctga agttgggaca 300

 aaattgaaca aacaagatga gtttggtgct ttggaaagtg tgaaagctgc 350

 tagtgaactc tattctcctt tatcaggaga agtaactgaa attaatgaag 400

 ctcttgcaga aaatccagga cttgtaaaca aatcttgtta tgaagatggt 450

 tggctgatca agatgacact gagtaaccct tcagaactag atgaacttat 500

 gagtgaagaa gcatatgaga aatacataaa atctattgag gagtgaaaat 550

 ggaactccta aataaactag tatgaaataa cgcaagccag cagagttgtc 600

 ttaaattagt ggtggataga agacttagaa tagaaacttt tagtattacc 650

 gatggggaaa aaaaaactac tgttaacact gctaatgaaa gaaaatgccc 700

 tttaactttc taatgattat agataaatat aatatgcgtc tttttcacaa 750

 tatcctatga tttttagact aggctctagt gttcagaatt catgaaatta 800

 tccatggtaa aaactagtta taaaaattac ataattcaaa gataacattg 850

 ttattcttaa gccttatata atattgtaac ttgcatgtat ccatacctgg 900

 atttgggatg aaatacttaa tgatctttcc attggaaata actggaagtg 950

 aagaggtttt gttgcttgta cagtgtcaga tgaggaacac cactatctta 1000

 attttgcgat acactgcatt tgctggtgct atttttatac agtgaagcaa 1050

 cagctttgca gcaaaataat aaaatacttc ttcgtt 1086

<210> 2735
<211> 173
<212> PRT
<213> Homo sapien

<400> 2735
 Met Ala Leu Arg Val Val Arg Ser Val Arg Ala Leu Leu Cys Thr
   1               5                  10                  15

 Leu Arg Ala Val Pro Leu Pro Ala Ala Pro Cys Pro Pro Arg Pro
                  20                  25                  30

 Trp Gln Leu Gly Val Gly Ala Val Arg Thr Leu Arg Thr Gly Pro
                  35                  40                  45

 Ala Leu Leu Ser Val Arg Lys Phe Thr Glu Lys His Glu Trp Val
                  50                  55                  60

 Thr Thr Glu Asn Gly Ile Gly Thr Val Gly Ile Ser Asn Phe Ala
                  65                  70                  75

 Gln Glu Ala Leu Gly Asp Val Val Tyr Cys Ser Leu Pro Glu Val
                  80                  85                  90

 Gly Thr Lys Leu Asn Lys Gln Asp Glu Phe Gly Ala Leu Glu Ser
                  95                 100                 105

 Val Lys Ala Ala Ser Glu Leu Tyr Ser Pro Leu Ser Gly Glu Val
                 110                 115                 120

 Thr Glu Ile Asn Glu Ala Leu Ala Glu Asn Pro Gly Leu Val Asn
                 125                 130                 135

 Lys Ser Cys Tyr Glu Asp Gly Trp Leu Ile Lys Met Thr Leu Ser
                 140                 145                 150

 Asn Pro Ser Glu Leu Asp Glu Leu Met Ser Glu Glu Ala Tyr Glu
                 155                 160                 165

 Lys Tyr Ile Lys Ser Ile Glu Glu
                 170

<210> 2736
<211> 1378
<212> DNA
<213> Homo sapien

<400> 2736
 cgacgcggga gccgcacgcg ccggacgagg ctcgctgcgc tccctgttgc 50

 ccagcgcggg cccgttgagg cggagccctc agttcccggc caggacacgg 100

 tctgggccgc cgaatctccg gccgaagagc ggcggcggca gcggcggaaa 150

 aaaatgaaga atgaaattgc tgccgttgtc ttctttttca caaggctagt 200

 tcgaaaacat gataagttga aaaaagaggc agttgagagg tttgctgaga 250

 aattgaccct aatacttcaa gaaaaatata aaaatcactg gtatccagaa 300

 aaaccatcga aaggacaggc ctacagatgt attcgtgtca ataaatttca 350

 gagagttgat cctgatgtcc tgaaagcctg tgaaaacagc tgcatcttgt 400

 atagtgacct gggcttgcca aaggagctca ctctctgggt ggacccatgt 450

 gaggtgtgct gtcggtatgg agagaaaaac aatgcattca ttgttgccag 500

 ctttgaaaat aaagatgaga acaaggatga gatctccagg aaagttacca 550

 gggcccttga taaggttacc tctgattatc attcaggatc ctcttcttca 600

 gatgaagaaa caagtaagga aatggaagtg aaacccagtt cggtgactgc 650

 agccgcaagt cctgtgtacc agatttcaga acttatattt ccacctcttc 700

 caatgtggca ccctttgccc agaaaaaagc caggaatgta tcgagggaat 750

 ggccatcaga atcactatcc tcctcctgtt ccatttggtt atccaaatca 800

 gggaagaaaa aataaaccat atcgcccaat tccagtgaca tgggtacctc 850

 ctcctggaat gcattgtgac cggaatcact ggattaatcc tcacatgtta 900

 gcacctcact aacttcgttt ttgattgtgt tggtgtcatg ttgagaaaaa 950

 ggtagaataa accttactac acattaaaag ttaaaagttc ttactaatag 1000

 tagtgaagtt agatgggcca aaccatcaaa cttattttta tagaagttat 1050

 tgagaataat ctttcttaaa aaatatatgc actttagata ttgatatagt 1100

 ttgagaaatt ttattaaagt tagtcaagtg cctaagtttt taatattgga 1150

 cttgagtatt tatatattgt gcatcaactc tgttggatac gagaacactg 1200

 tagaagtgga cgatttgttc tagcaccttt gagaatttac tttatggagc 1250

 gtatgtaagt tatttatata caaggaaatc tattttatgt cgttgtttaa 1300

 gagaattgtg tgaaatcatg tagttgcaaa taaaaaatag tttgaggcat 1350

 gaaaaaaaaa aaaaaaaaaa aaaaaaaa 1378

<210> 2737
<211> 252
<212> PRT
<213> Homo sapien

<400> 2737
 Met Lys Asn Glu Ile Ala Ala Val Val Phe Phe Phe Thr Arg Leu
   1               5                  10                  15

 Val Arg Lys His Asp Lys Leu Lys Lys Glu Ala Val Glu Arg Phe
                  20                  25                  30

 Ala Glu Lys Leu Thr Leu Ile Leu Gln Glu Lys Tyr Lys Asn His
                  35                  40                  45

 Trp Tyr Pro Glu Lys Pro Ser Lys Gly Gln Ala Tyr Arg Cys Ile
                  50                  55                  60

 Arg Val Asn Lys Phe Gln Arg Val Asp Pro Asp Val Leu Lys Ala
                  65                  70                  75

 Cys Glu Asn Ser Cys Ile Leu Tyr Ser Asp Leu Gly Leu Pro Lys
                  80                  85                  90

 Glu Leu Thr Leu Trp Val Asp Pro Cys Glu Val Cys Cys Arg Tyr
                  95                 100                 105

 Gly Glu Lys Asn Asn Ala Phe Ile Val Ala Ser Phe Glu Asn Lys
                 110                 115                 120

 Asp Glu Asn Lys Asp Glu Ile Ser Arg Lys Val Thr Arg Ala Leu
                 125                 130                 135

 Asp Lys Val Thr Ser Asp Tyr His Ser Gly Ser Ser Ser Ser Asp
                 140                 145                 150

 Glu Glu Thr Ser Lys Glu Met Glu Val Lys Pro Ser Ser Val Thr
                 155                 160                 165

 Ala Ala Ala Ser Pro Val Tyr Gln Ile Ser Glu Leu Ile Phe Pro
                 170                 175                 180

 Pro Leu Pro Met Trp His Pro Leu Pro Arg Lys Lys Pro Gly Met
                 185                 190                 195

 Tyr Arg Gly Asn Gly His Gln Asn His Tyr Pro Pro Pro Val Pro
                 200                 205                 210

 Phe Gly Tyr Pro Asn Gln Gly Arg Lys Asn Lys Pro Tyr Arg Pro
                 215                 220                 225

 Ile Pro Val Thr Trp Val Pro Pro Pro Gly Met His Cys Asp Arg
                 230                 235                 240

 Asn His Trp Ile Asn Pro His Met Leu Ala Pro His
                 245                 250

<210> 2738
<211> 2173
<212> DNA
<213> Homo sapien

<400> 2738
 cggtccggac agccgcgcgc tgagggtctc ggggcgggcg ccgcgggacc 50

 tctccgggcc atggcagccc ctgtcaaagg gaacaggaag cagtccacgg 100

 agggtgacgc cctagaccca cctgcatccc ccaaacctgc tggcaagcag 150

 aacggaatcc agaaccccat ctcgctggag gactcccccg aggcaggcgg 200

 ggagcgggag gaggagcagg agcgggagga ggagcaggcc ttcctggtca 250

 gcctctacaa gttcatgaag gagcgacaca cgcccatcga gagggtgccc 300

 catctcggct tcaagcagat taacctgtgg aagatctaca aagcagtgga 350

 gaagctgggg gcctatgagc tggtgaccgg gcgccgcctc tggaagaacg 400

 tgtacgacga gctggggggc agcccaggca gcaccagcgc ggccacgtgc 450

 acgcgccgcc actacgagag gctggtcctg ccatacgtgc ggcacctgaa 500

 gggggaggat gacaagccgc tgcccacctc caagcccagg aaacagtaca 550

 agatggctaa ggagaacagg ggggatgatg gggccaccga gaggccgaag 600

 aaggccaagg aggagcggcg catggaccag atgatgccag gaaagaccaa 650

 agcagatgct gctgacccag caccacttcc cagccaggag ccccccagga 700

 acagcacaga acagcagggc ctggcctctg ggtcttctgt gtcctttgtg 750

 ggtgccagcg gctgtcctga ggcctacaag cggctcctat ccagcttcta 800

 ctgcaagggg acacacggca tcatgtcacc actggccaaa aagaagctcc 850

 tggcccaggt gagcaaggtg gaggccttgc agtgccagga ggagggctgc 900

 cgccatgggg cagagcccca ggcgtcccca gctgttcacc tcccagagag 950

 tccccagagc cccaaagggc tgactgagaa ctccaggcac cggctgaccc 1000

 ctcaggaggg attgcaggcc ccaggtggca gcctcagaga ggaggcgcag 1050

 gcaggcccct gcccggcagc ccccatcttc aagggctgct tctacaccca 1100

 ccccaccgag gtgctgaagc ctgtcagcca gcaccccagg gacttcttct 1150

 ctagacttaa agatggggtg ctattggggc ctcctggcaa agaggggctg 1200

 tcagtgaaag agccccagct ggtgtggggc ggagacgcta accgcccttc 1250

 tgcgttccat aaaggtggct ccagaaaggg catcctctac cccaagccca 1300

 aagcctgctg ggtgtccccc atggccaagg tcccagccga gagccccacg 1350

 ctcccgccca ccttccccag tagcccaggc ctgggcagca agcgcagcct 1400

 ggaggaagag ggtgctgccc acagtgggaa gagactgcgg gccgtgtctc 1450

 cctttcttaa ggaggcggat gccaagaagt gtggggccaa acctgcaggg 1500

 tccggcctgg tctcctgcct tctgggccca gccctggggc ctgtgccccc 1550

 agaggcctac aggggcacca tgctgcactg cccgctgaac ttcactggca 1600

 ccccgggccc cttgaagggc caggctgcac tccccttcag ccccctggtc 1650

 atcccggcct tcccggccca cttcctggcc accgcaggcc cctcgcccat 1700

 ggccgctggc ctgatgcact tccccccaac gtccttcgac agtgccctcc 1750

 gccacagact ttgcccggcc tcatctgcct ggcacgcacc accagtcaca 1800

 acctatgcag cgccccactt cttccacctc aacaccaagc tgtaggccag 1850

 cccatggtgt tgtgtacact gtggagtcga caggggccta caacaggcag 1900

 gtactgctgc cagggggctc tgaactagtg cctgctaccc aggacacccg 1950

 ggccatgccc ctggctgggc agcctggcac aagtgaagaa gaaggcagtg 2000

 ggaaaactgg gtttatctca aggcagcagc ctgagcccag gagcagagga 2050

 cccagttgtt ataaggcgct gggagaggat gggcagctcc cactgcccca 2100

 gagcggasst cgaagcaccc aggttgccca cggaaaatcc aataaaaaga 2150

 caccagtgtg aatccaaaaa aaa 2173

<210> 2739
<211> 614
<212> PRT
<213> Homo sapien

<400> 2739
 Arg Ser Gly Gln Pro Arg Ala Glu Gly Leu Gly Ala Gly Ala Ala
   1               5                  10                  15

 Gly Pro Leu Arg Ala Met Ala Ala Pro Val Lys Gly Asn Arg Lys
                  20                  25                  30

 Gln Ser Thr Glu Gly Asp Ala Leu Asp Pro Pro Ala Ser Pro Lys
                  35                  40                  45

 Pro Ala Gly Lys Gln Asn Gly Ile Gln Asn Pro Ile Ser Leu Glu
                  50                  55                  60

 Asp Ser Pro Glu Ala Gly Gly Glu Arg Glu Glu Glu Gln Glu Arg
                  65                  70                  75

 Glu Glu Glu Gln Ala Phe Leu Val Ser Leu Tyr Lys Phe Met Lys
                  80                  85                  90

 Glu Arg His Thr Pro Ile Glu Arg Val Pro His Leu Gly Phe Lys
                  95                 100                 105

 Gln Ile Asn Leu Trp Lys Ile Tyr Lys Ala Val Glu Lys Leu Gly
                 110                 115                 120

 Ala Tyr Glu Leu Val Thr Gly Arg Arg Leu Trp Lys Asn Val Tyr
                 125                 130                 135

 Asp Glu Leu Gly Gly Ser Pro Gly Ser Thr Ser Ala Ala Thr Cys
                 140                 145                 150

 Thr Arg Arg His Tyr Glu Arg Leu Val Leu Pro Tyr Val Arg His
                 155                 160                 165

 Leu Lys Gly Glu Asp Asp Lys Pro Leu Pro Thr Ser Lys Pro Arg
                 170                 175                 180

 Lys Gln Tyr Lys Met Ala Lys Glu Asn Arg Gly Asp Asp Gly Ala
                 185                 190                 195

 Thr Glu Arg Pro Lys Lys Ala Lys Glu Glu Arg Arg Met Asp Gln
                 200                 205                 210

 Met Met Pro Gly Lys Thr Lys Ala Asp Ala Ala Asp Pro Ala Pro
                 215                 220                 225

 Leu Pro Ser Gln Glu Pro Pro Arg Asn Ser Thr Glu Gln Gln Gly
                 230                 235                 240

 Leu Ala Ser Gly Ser Ser Val Ser Phe Val Gly Ala Ser Gly Cys
                 245                 250                 255

 Pro Glu Ala Tyr Lys Arg Leu Leu Ser Ser Phe Tyr Cys Lys Gly
                 260                 265                 270

 Thr His Gly Ile Met Ser Pro Leu Ala Lys Lys Lys Leu Leu Ala
                 275                 280                 285

 Gln Val Ser Lys Val Glu Ala Leu Gln Cys Gln Glu Glu Gly Cys
                 290                 295                 300

 Arg His Gly Ala Glu Pro Gln Ala Ser Pro Ala Val His Leu Pro
                 305                 310                 315

 Glu Ser Pro Gln Ser Pro Lys Gly Leu Thr Glu Asn Ser Arg His
                 320                 325                 330

 Arg Leu Thr Pro Gln Glu Gly Leu Gln Ala Pro Gly Gly Ser Leu
                 335                 340                 345

 Arg Glu Glu Ala Gln Ala Gly Pro Cys Pro Ala Ala Pro Ile Phe
                 350                 355                 360

 Lys Gly Cys Phe Tyr Thr His Pro Thr Glu Val Leu Lys Pro Val
                 365                 370                 375

 Ser Gln His Pro Arg Asp Phe Phe Ser Arg Leu Lys Asp Gly Val
                 380                 385                 390

 Leu Leu Gly Pro Pro Gly Lys Glu Gly Leu Ser Val Lys Glu Pro
                 395                 400                 405

 Gln Leu Val Trp Gly Gly Asp Ala Asn Arg Pro Ser Ala Phe His
                 410                 415                 420

 Lys Gly Gly Ser Arg Lys Gly Ile Leu Tyr Pro Lys Pro Lys Ala
                 425                 430                 435

 Cys Trp Val Ser Pro Met Ala Lys Val Pro Ala Glu Ser Pro Thr
                 440                 445                 450

 Leu Pro Pro Thr Phe Pro Ser Ser Pro Gly Leu Gly Ser Lys Arg
                 455                 460                 465

 Ser Leu Glu Glu Glu Gly Ala Ala His Ser Gly Lys Arg Leu Arg
                 470                 475                 480

 Ala Val Ser Pro Phe Leu Lys Glu Ala Asp Ala Lys Lys Cys Gly
                 485                 490                 495

 Ala Lys Pro Ala Gly Ser Gly Leu Val Ser Cys Leu Leu Gly Pro
                 500                 505                 510

 Ala Leu Gly Pro Val Pro Pro Glu Ala Tyr Arg Gly Thr Met Leu
                 515                 520                 525

 His Cys Pro Leu Asn Phe Thr Gly Thr Pro Gly Pro Leu Lys Gly
                 530                 535                 540

 Gln Ala Ala Leu Pro Phe Ser Pro Leu Val Ile Pro Ala Phe Pro
                 545                 550                 555

 Ala His Phe Leu Ala Thr Ala Gly Pro Ser Pro Met Ala Ala Gly
                 560                 565                 570

 Leu Met His Phe Pro Pro Thr Ser Phe Asp Ser Ala Leu Arg His
                 575                 580                 585

 Arg Leu Cys Pro Ala Ser Ser Ala Trp His Ala Pro Pro Val Thr
                 590                 595                 600

 Thr Tyr Ala Ala Pro His Phe Phe His Leu Asn Thr Lys Leu
                 605                 610

<210> 2740
<211> 1433
<212> DNA
<213> Homo sapien

<400> 2740
 aatttggggc caagattaac acccctcctg caggaggaag acagccacca 50

 gcggctgctc atggggctga tggtgtctga gctaaaagac cattttttga 100

 gacacctaca gggtgtagaa aagaagaaaa ttgaacagat ggttctggac 150

 tacatttcaa aactgctgga tctcatttgc cacatcgtag aaaccaattg 200

 gaggaaacat aatcttcatt cctgggttct ccacttcaat agtcgtggca 250

 gtgctgctga atttgcagtt tttcacatca tgaccaggat tctggaagct 300

 acaaacagtt tgtttttacc tctgcctcct ggttttcata ctctgcacac 350

 catcctcggg gtccagtgtc tccctttgca taacctgctg cattgcattg 400

 acagtggagt gttgcttctc actgaaacag ctgtcataag gctcatgaaa 450

 gatctggata atacagagaa aaatgaaaaa ctgaaattca gtatcattgt 500

 gcggcttcct ccgcttattg ggcagaagat ttgtagactt tgggatcatc 550

 ctatgagttc taacatcatt tcgcggaacc acgtgacgcg actgcttcag 600

 aactataaga aacagcctcg gaattctatg attaacaagt catcgttcag 650

 tgtagaattt ctgcctctga actacttcat tgaaattctg acagatatag 700

 agtcctccaa tcaagccctg tatccttttg aaggacatga caatgtggat 750

 gcagaatttg tagaggaagc agctctgaaa cacaccgcga tgcttttagg 800

 cttatgaaaa agaaaacgca attggatctg ctgctgccat tttaatcttg 850

 ctcattaacc ttactcctct gagaattctt taacaatatt taaaattggt 900

 aacaaaaata gtttagccat aattgtttag ccatgtgagt ttcaggttgg 950

 tacacgttca gacagaactg ctgtatcaca ttccaatttt gaatagccag 1000

 tgagcaatca agtgtagaga aatgataaat ggcctaagaa ggcatacagt 1050

 ggcataaacg atgctcttcc tagtagctta ataggccaca agctagtttc 1100

 tgttgcactc tgaaataaaa tatgctttaa aaatgtaggg aacagtgctt 1150

 agaaaagcaa aaactaggtg tgtcattgaa ataataggca taaaaattaa 1200

 atgttacata agaacactat ttggaaagag ggtcctttta aaaactgaat 1250

 ttgtactaaa tcagatttgc catgtcccag tccagaataa tttgtactta 1300

 gtatttgcag cagggtttgt ctttgtgaat tcagatgaaa catatttatt 1350

 tttttttatt tataaaaggt tgatttagga atattttgtc agtcattaaa 1400

 aaacctgaaa acataaaaaa aaaaaaaaaa aaa 1433

<210> 2741
<211> 268
<212> PRT
<213> Homo sapien

<400> 2741
 Asn Leu Gly Pro Arg Leu Thr Pro Leu Leu Gln Glu Glu Asp Ser
   1               5                  10                  15

 His Gln Arg Leu Leu Met Gly Leu Met Val Ser Glu Leu Lys Asp
                  20                  25                  30

 His Phe Leu Arg His Leu Gln Gly Val Glu Lys Lys Lys Ile Glu
                  35                  40                  45

 Gln Met Val Leu Asp Tyr Ile Ser Lys Leu Leu Asp Leu Ile Cys
                  50                  55                  60

 His Ile Val Glu Thr Asn Trp Arg Lys His Asn Leu His Ser Trp
                  65                  70                  75

 Val Leu His Phe Asn Ser Arg Gly Ser Ala Ala Glu Phe Ala Val
                  80                  85                  90

 Phe His Ile Met Thr Arg Ile Leu Glu Ala Thr Asn Ser Leu Phe
                  95                 100                 105

 Leu Pro Leu Pro Pro Gly Phe His Thr Leu His Thr Ile Leu Gly
                 110                 115                 120

 Val Gln Cys Leu Pro Leu His Asn Leu Leu His Cys Ile Asp Ser
                 125                 130                 135

 Gly Val Leu Leu Leu Thr Glu Thr Ala Val Ile Arg Leu Met Lys
                 140                 145                 150

 Asp Leu Asp Asn Thr Glu Lys Asn Glu Lys Leu Lys Phe Ser Ile
                 155                 160                 165

 Ile Val Arg Leu Pro Pro Leu Ile Gly Gln Lys Ile Cys Arg Leu
                 170                 175                 180

 Trp Asp His Pro Met Ser Ser Asn Ile Ile Ser Arg Asn His Val
                 185                 190                 195

 Thr Arg Leu Leu Gln Asn Tyr Lys Lys Gln Pro Arg Asn Ser Met
                 200                 205                 210

 Ile Asn Lys Ser Ser Phe Ser Val Glu Phe Leu Pro Leu Asn Tyr
                 215                 220                 225

 Phe Ile Glu Ile Leu Thr Asp Ile Glu Ser Ser Asn Gln Ala Leu
                 230                 235                 240

 Tyr Pro Phe Glu Gly His Asp Asn Val Asp Ala Glu Phe Val Glu
                 245                 250                 255

 Glu Ala Ala Leu Lys His Thr Ala Met Leu Leu Gly Leu
                 260                 265

<210> 2742
<211> 5312
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2189, 2194, 2196, 2198, 2208, 2210, 2213
<223> Unknown base

<400> 2742
 gaaatcagaa aaatgattaa gtgagataag tacctgggtg acacagatat 50

 tagcccgttg gtaaaagaca acaaatatta gcttaaaatc tgcatatgta 100

 gaatcatttt cattagattt agagcttgaa gcaccttggc tctcagctac 150

 tttaaactcc tccccatata aatcagggca ccaataaata agtttcagct 200

 ttttaaaccc tggtttgatg ttaagcatta taaagtacga agtttgttac 250

 cacagtagag ataatttagt agaaaaatgc tttgaggctt cagtatttgt 300

 aagattttgc attagccaga tgctaggttg ttgaaggcat ttcagtgttg 350

 ataatagcct gagcagactt ctttacaaat gggatctgtt tctatatgtg 400

 tatatgccca cttaccattc agagagactg gtctttctct ttgtcttcct 450

 tcacattgct gtgtcagttc tacacctagt cttttcagca cttagcaaat 500

 tcaaattttg atttttttgt cagcttagtt cactttaagg catattggca 550

 tggtgtgtga aagtgatgtt ttgccccagt attgaggact tttagatcca 600

 aataatgact cattaaatat aattatgttt taagtatact gaatttctgt 650

 tagcttaaaa tgttaattct caggaatgat tttctcacac tttgtgttgg 700

 ctaataataa aagcactgtt ttattctcaa aactcctttt tcaaaaatta 750

 gggagagagc agtagtgatc atttatgtga gcccctttga aatgatggtg 800

 tcagagtgca gagaaacaat ggagttttga tgccaaaaag gtttttttgc 850

 agtaaaagta aaaatttgga attagttggc atatagagga acccttttgt 900

 actggaacgt atgaggctgg attgtgaaaa ggtaatcttt cgattgctag 950

 acttggttaa cttagggctg caaatctttt tcttctatca aggtcactta 1000

 atatggaatg tttttgtcag actgtccttt gttggaatac tttagctgtt 1050

 cagctacttt gactcctagg agagaattta gttaaggttc aaagtaatta 1100

 actggctttg ccagtggtga gtcccacacc attattcact tagtagtcat 1150

 ataaatgttt ttatttaaac ttctctctct tcaatgctga gaataaggct 1200

 ttaaattact gattcacctt taaaggaatg ttgtgagaat tgatgtaatt 1250

 tctgtttctg tttccatcta aacttcttta taaaaagagg gattagtttt 1300

 tttgttttgg ggtaagcacc taatttatcc agtaaccaac aaccctaacc 1350

 attggcatat atagtctttc actcagaaat aaacaaaaac tgtttggtat 1400

 atctgtatca ttgctaatct tgtgcacttt actttttggg cagtaccata 1450

 catagtctga ggctattgac ttaaaccaat aactgtactt tatgtaatga 1500

 ctcttaaatt tggttacctg ggttcacagc ttgcttgaag agaaaggatg 1550

 ctagaataaa gtaagcagct gaagagcgag caaatcaaga caaaacacag 1600

 tggtctcaga tttttcgtag tgtgggaaca gtggttttgc tctataccac 1650

 tgaaaagcac tataacataa ttgttgtcca tgatactgaa gcttttcccc 1700

 tcacttctag gttgtttaca ttcagagctc tatcaataag aggaatacat 1750

 attacagtga attcgacaac cgcacaagtt ggcagtaggt atccccaacc 1800

 taatttatct tggtaaattc accctgtttc ctagtgctgc tggataaaag 1850

 agtgtttact ttttattgct cttagacaga gtagtctaga taagttttca 1900

 atttatcaac atagcctaga cttctgtaag tggaatgttc attagtaact 1950

 catctttttg ttgttataat tggaaacaga aacgaggctt attgctattg 2000

 cagaaatccc aaactggcaa aggccagtat atatggtatt ccataatata 2050

 accagctttt gaaatttatg tgtttggatt agtgccttct ggttaccagt 2100

 attgactctg ctagtttgca cctttccgtt cttaacagaa aatttgtatt 2150

 tgttattcct cttaaatttt gtcgtaacta gtgaagggng tatnangnta 2200

 acgaatancn tgnatgacat tgacatactt tatgtgcagc ctttatttag 2250

 gttcagtgaa accaggtagt tctgtatttg tgttgtagcc taaatgttgt 2300

 ttcttttata tccattaaaa acttaaagtt acttatgttc tgtgatctta 2350

 attttgttgt gtttccattg taggttgata ggtatatcga gaacaggtac 2400

 gtgacaacag tttatattcc atgatagaaa gctaaagtcc atagaaagca 2450

 caaaatcgtg ttcacacatt agtgtaccca cacatagaaa gcacaagact 2500

 aatagtattc tctgtatccc acaagtgcca gtcataaagg ccaccaggta 2550

 tttgtctcag agttgctatg agcactacag tattgataag cccaagacaa 2600

 tgcggtatct aaactggtcc taatggtaag ggacccaaag gaataatctc 2650

 aataagtttg taccacattg atggagggag agaatataaa tgtcaagaat 2700

 gccaaaatta tatttggggg ttactagcta aaatggggtt tgagggcttt 2750

 ttactgcaac ttgaaactgg agaaataggg acagatgtct aggtttttgg 2800

 tgggtggaac aggtgacata tttctgtttt aagctgtagt gtgattgggg 2850

 ttttttgtaa aaaatcttaa atcttttagg aaatattacc tcttaacagt 2900

 gcccccccaa acatgcagaa agtcatactt taacagggca aatactactt 2950

 gtctttgatt ttttttgtgt acgtttgtat gtgagagatg aagttacctt 3000

 tatttttttc ctatacttga ctgtgcttca ttttaataaa ggataatttg 3050

 atctgagtgt tctgagcatc agactaattc tgaagcatat ttgctagagg 3100

 agctactttg cttttcacaa tggggtggag aggattcttt cacttgtccc 3150

 attaaccctc ttctagtcta gatgagatga aatctgttaa tgtgtgtgta 3200

 gaagaaaacg tatgttcttc tactcagcat tgcccttttc cacctcctca 3250

 cttcacctcc gagtagcttg tttatcaaga atgaatgaat gtctttgtct 3300

 taaattttgc ccatgtgtta aaagatgtaa ttctcagaat gggagagaaa 3350

 tgactacctt tgttcctact cttttatata attatccttt tagggaaaga 3400

 cttggtcaac tctaatatat ctagaaggaa gactatatct ggtgtagact 3450

 aatatgagat gttttagaag agttaacctg aacactttga gggagagatt 3500

 attcttgcca gcaaaaagct agccaggaat gagcctacca cattatttga 3550

 gaatatcaaa cctcaggcct ggggggatga ggggaagaag attaccagaa 3600

 gtgcaggaaa gagaagtttg aggaacaccc ttggcttagc aacatgtgat 3650

 aatgcaaagc tgttataacc tgttaatcct acgtactatg tgttctgtac 3700

 ctttacatgt ttttaaattt aagatagttt gtaagaactg tacaaaaaaa 3750

 tgcttctgga gatttctttg gcagaaatgc ctttcatcta taatttcatg 3800

 gagaactgct ttaattagcc taggtgaaaa gtagtcctag cagtgtaaat 3850

 atgtataatt agagttttct aatttcactg tgagatctct aacttttgag 3900

 tggcaaacag atcaagtctt ttgctcatag acttttctgt ggggttatta 3950

 aaatgcaaaa gctttatttt ttttaataat gccatactcc attagtgtca 4000

 gatgatggta tggaatttgt tcccttgctt tcccccactg ttactgcttc 4050

 agtttataga ttgccagcag agttcagaaa tagagcaggg atttacccgt 4100

 tctttgcttg gacatcccat tttcttttgt ccagacccat gttggcaatc 4150

 atgtatgaac tgtgttatac ttctcagtgc tttctttttt ctttttgata 4200

 agatggatat caaaaatagt tgctgtgcaa aagttagtag tcttcttcaa 4250

 gaagaaaacc aattcttttt ctaataatat cctgtgaaat tgcttcattc 4300

 aattcattta tttttaagcc aaatgtcagc agagtgctgc tgcttttatc 4350

 tagtaatttt gatatgtaag tattaatgca tttttaaaag atgtctacat 4400

 tgaaacatgt tcttcccagt gtcctgctta tgatgctttg ttcagatttt 4450

 ttgtaagaga ccagttagta cactgggggt gtatattgtg tacatgtgtc 4500

 attttagtta ggcattgtag gccaaatgtg attataaatg aagttgatga 4550

 acattaattt tgttattagt gagttttttg aattgtaaat ggatttccag 4600

 tttaccttct gttgtctaca gcttttttaa ttttaaggtt ttactaattg 4650

 tatccatctc attgtacagt gttttagttg caagcagaaa gtagaatttg 4700

 gtataaagca ggttatttct atattgaaag gagtacagtt gaaattgtag 4750

 atttaagatt gttaaaatca tgacaattct aacttgtcta ttctaaccta 4800

 ttgtgtacaa tctgattttt taaaattgta aacatgtatg atcttggttt 4850

 catgtgtttt tgaaagtgtt attgtttaaa aaatgaaaaa agcatatctg 4900

 ctaaagagct gtcagttttc attactgact ctgtaaaata cactgttctt 4950

 tgtgtactgt gtgttatttt gccagctgct gcattagcct tcaaaagtat 5000

 ttggaaactt aagatgaact acatttcttg caaagtacat tcctttctgt 5050

 ggtattttgt cctgtaactg aagtatagta attattttat ggaaatgtta 5100

 gcaattctgt accaactttg aataaaatga aaaatttata tttctgtgac 5150

 taagtatttt cagtatgaac actgccacaa tgtagtgttc tgggtctcag 5200

 agttgaagaa gagtattgta cctcgagttt ctttatgccc ttggcccata 5250

 gaatggtttc cagtgaattt ccccctacta atattttagt catttttaat 5300

 ctttgtaaac ac 5312

<210> 2743
<211> 89
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2189, 2194, 2196, 2198, 2208, 2210, 2213
<223> Unknown amino acid

<400> 2743
 Met Val Trp Asn Leu Phe Pro Cys Phe Pro Pro Leu Leu Leu Leu
   1               5                  10                  15

 Gln Phe Ile Asp Cys Gln Gln Ser Ser Glu Ile Glu Gln Gly Phe
                  20                  25                  30

 Thr Arg Ser Leu Leu Gly His Pro Ile Phe Phe Cys Pro Asp Pro
                  35                  40                  45

 Cys Trp Gln Ser Cys Met Asn Cys Val Ile Leu Leu Ser Ala Phe
                  50                  55                  60

 Phe Phe Leu Phe Asp Lys Met Asp Ile Lys Asn Ser Cys Cys Ala
                  65                  70                  75

 Lys Val Ser Ser Leu Leu Gln Glu Glu Asn Gln Phe Phe Phe
                  80                  85

<210> 2744
<211> 883
<212> DNA
<213> Homo sapien

<400> 2744
 gaattcccgg cgggtatcag agccatcaga accgccacca tgacggtggg 50

 caagagcagc aagatgctgc agcatattga ttacaggatg aggtgcatcc 100

 tgcaggacgg ccggatcttc attggcacct tcaaggcttt tgacaagcac 150

 atgaatttga tcctctgtga ctgtgatgag ttcagaaaga tcaagccaaa 200

 gaactccaaa caagcagaaa gggaagagaa gcgagtcctc ggtctggtgc 250

 tgctgcgagg ggagaatctg gtctcaatga cagtagaggg acctcctccc 300

 aaagatactg gtattgctcg agttccactt gctggagctg ccgggggccc 350

 agggatcggc agggctgctg gcagaggaat cccagctggg gttcccatgc 400

 cccaggctcc tgcaggactt gctgggccag tccgtggggt tggcgggcca 450

 tcccaacagg tgatgacccc acaaggaaga ggtactgttg cagccgctgc 500

 agctgctgcc acagccagta ttgccggggc tccaacccag tacccacctg 550

 gccgtggggg tcctccccca cctatgggcc gaggagcacc ccctccaggc 600

 atgatgggcc cacctcctgg tatgagacct cctatgggtc ccccaatggg 650

 gatcccccct ggaagaggga ctccaatggg catgccccct ccgggaatgc 700

 ggcctcctcc ccctgggatg cgagggcccc ctcccccggg aatgcgccca 750

 ccaaggccct agactcatct tggccctcct cagctccctg cctgtttccc 800

 gtaaggctgt acatagtcct tttatctcct tgtggcctat gaaactggtt 850

 tataataaac tcttaagaga acattataat tgc 883

<210> 2745
<211> 240
<212> PRT
<213> Homo sapien

<400> 2745
 Met Thr Val Gly Lys Ser Ser Lys Met Leu Gln His Ile Asp Tyr
   1               5                  10                  15

 Arg Met Arg Cys Ile Leu Gln Asp Gly Arg Ile Phe Ile Gly Thr
                  20                  25                  30

 Phe Lys Ala Phe Asp Lys His Met Asn Leu Ile Leu Cys Asp Cys
                  35                  40                  45

 Asp Glu Phe Arg Lys Ile Lys Pro Lys Asn Ser Lys Gln Ala Glu
                  50                  55                  60

 Arg Glu Glu Lys Arg Val Leu Gly Leu Val Leu Leu Arg Gly Glu
                  65                  70                  75

 Asn Leu Val Ser Met Thr Val Glu Gly Pro Pro Pro Lys Asp Thr
                  80                  85                  90

 Gly Ile Ala Arg Val Pro Leu Ala Gly Ala Ala Gly Gly Pro Gly
                  95                 100                 105

 Ile Gly Arg Ala Ala Gly Arg Gly Ile Pro Ala Gly Val Pro Met
                 110                 115                 120

 Pro Gln Ala Pro Ala Gly Leu Ala Gly Pro Val Arg Gly Val Gly
                 125                 130                 135

 Gly Pro Ser Gln Gln Val Met Thr Pro Gln Gly Arg Gly Thr Val
                 140                 145                 150

 Ala Ala Ala Ala Ala Ala Ala Thr Ala Ser Ile Ala Gly Ala Pro
                 155                 160                 165

 Thr Gln Tyr Pro Pro Gly Arg Gly Gly Pro Pro Pro Pro Met Gly
                 170                 175                 180

 Arg Gly Ala Pro Pro Pro Gly Met Met Gly Pro Pro Pro Gly Met
                 185                 190                 195

 Arg Pro Pro Met Gly Pro Pro Met Gly Ile Pro Pro Gly Arg Gly
                 200                 205                 210

 Thr Pro Met Gly Met Pro Pro Pro Gly Met Arg Pro Pro Pro Pro
                 215                 220                 225

 Gly Met Arg Gly Pro Pro Pro Pro Gly Met Arg Pro Pro Arg Pro
                 230                 235                 240

<210> 2746
<211> 3209
<212> DNA
<213> Homo sapien

<400> 2746
 ccccagtgaa tcttcaacag aatctcttaa agatctccag gaagttaaga 50

 gtaaacaaag gaaaaagaag aagactaaga ataaaaagaa taaagactca 100

 aaagaagacc aagtcccata tgtggtagaa aaggaagagc agttgaggaa 150

 agaacaagca aatccacact cagtcagtag acttataaaa gatgatgcaa 200

 gtgatgttca agaggattct gcaatggaag acaagttcta tagcctggat 250

 gaattgcata ttctggacat gatagagcag ggctcagctg gcaaagtaac 300

 tacagactat ggagaaactg aaaaggaaag gcttgctcgt caaaggcagc 350

 tttataaatt gcactatcag tgtgaagatt tcaaaagaca gttgagaaca 400

 gtgacttttc ggtggcaaga aaaccaaatg cagattaaaa agaaagacaa 450

 aattatcgca tctcttaatc aacaagttgc ttttggaatc aataaggttt 500

 ccaaattaca gcgtcaaatc catgctaaag ataatgaaat caagaacctt 550

 aaagagcaac tttctatgaa aagatctcag tgggaaatgg aaaaacataa 600

 tctggaaagc acaatgaaaa catacgtaag caaactgaac gcagaaacta 650

 gcagagcttt aacagccgag gtgtatttct tacagtgtcg tagggatttt 700

 ggtttgcttc atctagagca gactgaaaag gaatgtctca atcagcttgc 750

 cagggtgact cacatggcag caagcaacct agaatcactt caattaaagg 800

 ctgcggtaga cagttggaat gccattgtgg cagatgttag aaacaagatt 850

 gcattcctca ggacacagta caatgaacaa ataaacaaag tcaagcaagg 900

 atttgccttg agtaccttgc ctccagtcca gcttcctcct ccaccaccca 950

 gtcctgagat actgatgcag cagttcttag gaagacccct tgtgaaagaa 1000

 tctttcttta gacccatact tactgttcct caaatgcctg cagtttgccc 1050

 gggagtcgtc tctgcaactg gccaacctag agcccccctg atgactggca 1100

 tagcctgggc tctgccagcg cctgtgggag acgctgtgcc tcccagtgca 1150

 ggtctgcgga gtgatccctc catcatgaat tgggagagaa ttacagacag 1200

 gctgaaaact gcctttccac agcaaaccag aaaggaactt acagatttct 1250

 tacggaaatt gaaggatgct tatggaaaat ccttgtctga actgacattt 1300

 gatgaaattg tttgcaagat ttcccagttt attgacccca aaaagtctca 1350

 gagtcaagga aaatcagtgt caaatgttaa ttgtgtttca cctagtcatt 1400

 ctccatcaca gcctgatgct gcccagcccc caaaaccagc ctggaggcca 1450

 ctcacttcac gggtcctgcc acatgggaag gagccagtaa tccagatgag 1500

 gaagaggaag aagaagagcc ttgtgtgatc tgtcatgaga atctgtctcc 1550

 agaaaatctt tcagttttgc cttgcgctca caaattccat gctcagtgca 1600

 ttagaccatg gttgatgcaa caggggacat gtccaacgtg cagactccac 1650

 gttttgctac cagaagaatt ccctggtcac cccagccggc agttgcccaa 1700

 gatctgatac aaggtaccca tgaagagatt atgaactact tgaaggtgga 1750

 gactgtacgg tggtgtgttg gagctggctt gtaatgtctt atgagtgaca 1800

 atcgttagtt tgaggaattt tgtgagacag ttgtcaaatt gttgctagct 1850

 tgaaatctgc ggcaattgga gtatttacac catagaaatg ctataagtga 1900

 agacctacct ttcccttaag agctagttgt taaaccttta ccagcatacc 1950

 actggacctt gtctaaaatt tctttgtgtt cccagtgtct tgcccagtag 2000

 atacaagata aatattgcca gaatcagata tcaggaagta gtaagaaaag 2050

 gagttaatat gcaaactaaa tcactcgctc aattgaataa ttgagatctt 2100

 ctgttcattt gttccttgga ccttaatcat ttgcattttg gagaaaattt 2150

 tttctgcttt aaaagtctgt aatttcagtt tttgtgtcgg ggagagggaa 2200

 aaactatttg tctgtagttg ctttttgtga caaagtgaat acccactggg 2250

 ctaagtttca tatctaaagc ttgtcactaa gaattttcat ttttaggggt 2300

 caaaaaccta ttttgaaaat agtgttgtgt gaatgctgta agtgttgtac 2350

 atgtctctgg tttcagaatt aaaagaattc agagttacct tgtgagataa 2400

 atgttctttg cttcatattc acagtttcac ctccatttaa atttatgggg 2450

 aagaataaat gtttcctgac tcagaaacaa ttttgcctcc atatttcagt 2500

 gcaaatatat tttgaagtta cttttaaata tttatttaaa acctctgttt 2550

 ctgtaactgt atgttaaacg tattcttctg taatgagaat agactggaac 2600

 atgtgaggga aaaatattaa aaaaaagatg gcagtcatct agacatgtaa 2650

 aatgccaaga atgtcttaga attgcacaat ttagaattta tagagccttt 2700

 aatcaccttg tctagcacct tgtattagtc cattttcatg ctgctgataa 2750

 agacatacct gagattgggc aatttacaaa agaaagaggt ttaatggact 2800

 tacagtccac atgactaagg aggcctcaca atcatggtgg aaggcaaaga 2850

 ggagcaagtc acatcttaca tggatggcag cagacaagga gagagagctt 2900

 gtgcagggaa actcccattt ttwaaaccat cagatctcat gaggcttact 2950

 atcacgagaa cagcatggga aagacctgcc cccgtgatta aattatttyc 3000

 caccaggccc ctcccccaac atggaataat gggagataca agatatttgg 3050

 gtggagacac agagccaaac catatcacac cttaaggtca tggtcatatg 3100

 gctagttatc ttgtaaaacc aatgtttctt agttcatact tacaactgca 3150

 atttcacttt catttagaaa agaataaatg tttctttatt gdaaaaaaaa 3200

 aaaaaaaaa 3209

<210> 2747
<211> 3202
<212> DNA
<213> Homo sapien

<400> 2747
 atttctacag cagaaatgaa atcattacat ccgcttcaaa tgggtggact 50

 gaaagtggaa atgcccatga acttaaaggt tattatttat gaaaaacctc 100

 acttccatgg acaggctaaa gagtttagtg aacatataga ttctgttcct 150

 aattttttga aaaataatgg agattttcac agaattggat caattcgtgt 200

 cattggtgga gtgtgggttg cctatgaaaa agaacatttt aaaggccagc 250

 agtttctgct tgaagaagga gactttgaag acagtaatgc ttgtggtgca 300

 ttaagtagcc ctatcttgtc tttccggtac ttacaagcta attttataga 350

 atcttctgtc acactatttg aatctgacct agaaagtggg aagtttattg 400

 acattacaaa tcaggaaatt tctgatttgg aagaaattgg ctttggcagt 450

 aaaacaagat ccattcatgt taaaagtgga gtatgggttg cctaccagca 500

 aaagttcttc tgtggagaac aatacatttt agaaaaaggg aaatacaaat 550

 gcttttttga ctggggagga tcaaataata taatcatgtc gatacggcca 600

 atccaactgg aaccacttgg gataaatgaa cctccgcatt tgctcaaagc 650

 attcagcaaa ccagggttcc aaggtgaatg tatagatttt acagaagaaa 700

 cttctgattt gacttcactc atgccatgtt cttttaaagt tcttcgaggt 750

 tgctggctcc tctattacca agaagacatg tttgttaatc actgtgtgtt 800

 agaagaaggc ctctatgctg accttacttc ctgcggttgc ccagcatcta 850

 aagtcaaatc tctcaagccc attgactatg tttttgaaga accctccatc 900

 agcctttttg ctctggagca ttgtgaggga agagagttac atctagaaga 950

 ggctgtgaac tctgttctga acaaggacct acacttctac acccagtctg 1000

 tgtgggtaaa aagtggacta tggatagctt atgaaggatc caatttcttg 1050

 ggaagacaaa tcctactcag gcctaatgag atcccaaact ggacagcatt 1100

 cagcagatgg aaaacaattg gttccctccg tcctatgaag cagcctgcag 1150

 tgtacatcag aataaagaac cgtgcccagg gtgaatatct gacagtcact 1200

 ggaagtctag cagacaccag ggcaacatct gtgtgcattt ctccctatag 1250

 tggaaagaat actcagatct ggtactactg ccgaggactc tttaaatcca 1300

 aggccagtga tacatgtctt gatgtgattg gtggccggga cacacctgga 1350

 gctaaagtag ctctatggac tgaacatggg caattcaggc agaagtggag 1400

 actgaataaa aatggaacta tcagctctta tctcagtgat caacttgtcc 1450

 ttgatgttaa aggaggaaat tattgtgaca agactcatgt aattgtaaat 1500

 cagcccctgg agggagaaga aacacagaaa tgggacattg aaatattgtg 1550

 agagaatcaa catccctaga aagatcccta gaaagagcaa agaaggaaac 1600

 acatctgtca ttgtcttgtg gacgtggaaa ggaagctact gtcctcacac 1650

 tcctggatca ctgagcagaa tgaacatttt ctccagcctc tgagactatc 1700

 gctcttaacc atggaaaagc tcaaaatatt cttgccatta ctcagtgttc 1750

 ctataaagaa aatattatga tatcttggaa aggttctatt cctgatctcc 1800

 agctgtggtg agcaagtttc ctgaagtgtt tattttctct catatccacc 1850

 aaacgtgaat cctgttcctg atggcccgtt attggacact ggtgatgcta 1900

 ttatcctgta ttatttatta atatcctacc tagatgcttg tatgagtaca 1950

 aagcataaag aaacagattt ctataggtca agtcatactt ttgcaaacag 2000

 atgagtaatt ttttagcaac acctgaaaat atactaaact ttcctagata 2050

 aactttaagg tttctatact gaggctttta taatgaacgc acctcgttaa 2100

 gtatttatac ttgtaactaa ccccaggcag ggacctcagc tttgttagga 2150

 gtaaggcaca agaagtattt tctgtagcta ttgtttcctc agtccttcaa 2200

 actaaaaaag tacaaataaa taacctatgg ccaaacttgc actgttacgt 2250

 gttaaccaag acatcccttt aggtgacaag actctataac agtggttacc 2300

 tgtctccatg ttgacacttc atcctagatt taaggagagg catcaatttt 2350

 tttttttttt tgcctcaaga gaaatttcaa atatccaaat taaaacacag 2400

 tagcatttga accttgacct taccatctct ttaagtaaac gtggagttga 2450

 tttctctact aaataacaga aacctcagtt tttcactccc attgtaagta 2500

 acttttattt aagtaagtaa aatcaggtag gaaatcacct ttgacttagc 2550

 ttccagtagt cattaccacc ttttactgca caattcacaa gcatgttttc 2600

 ctggtgaatt ggactgaaaa ttacattttg acaacttttt ttccttttat 2650

 ccccaacttt tgccagaaag cagaaaaatg ctctattttt ataaagaaag 2700

 attaaattct ccaatgatat tttaaaaaat atcaacctac atgcacttta 2750

 gaatgtaaaa taacaatgac tattttaaac tcgaagaccc actattttga 2800

 gtatttttta tagactttaa atactgggtt tttttcctcc ttcaatctca 2850

 ggcttttctc catcttttaa gcagcctctg taactccctt ttgtccatag 2900

 gtgttgcgtg cctctcatct gtggggaagt attatttaat aaaatttatg 2950

 ttacaggata actttatttt aatgggcatg ggcttgtcta tacacaaagg 3000

 tatgtatatt ttcattataa aaaaccagtt taaaattttt tcttatttta 3050

 attgtttgaa atttttctag agccaaagaa gctctttaaa gaagttgttt 3100

 cttccaaaga acaaagccag gttaatgaca ttcaattcta aatgatacat 3150

 tggaattgtg ccttttctac cacactggat taaataaact tgtcaaaata 3200

 tg 3202

<210> 2748
<211> 511
<212> PRT
<213> Homo sapien

<400> 2748
 Met Lys Ser Leu His Pro Leu Gln Met Gly Gly Leu Lys Val Glu
   1               5                  10                  15

 Met Pro Met Asn Leu Lys Val Ile Ile Tyr Glu Lys Pro His Phe
                  20                  25                  30

 His Gly Gln Ala Lys Glu Phe Ser Glu His Ile Asp Ser Val Pro
                  35                  40                  45

 Asn Phe Leu Lys Asn Asn Gly Asp Phe His Arg Ile Gly Ser Ile
                  50                  55                  60

 Arg Val Ile Gly Gly Val Trp Val Ala Tyr Glu Lys Glu His Phe
                  65                  70                  75

 Lys Gly Gln Gln Phe Leu Leu Glu Glu Gly Asp Phe Glu Asp Ser
                  80                  85                  90

 Asn Ala Cys Gly Ala Leu Ser Ser Pro Ile Leu Ser Phe Arg Tyr
                  95                 100                 105

 Leu Gln Ala Asn Phe Ile Glu Ser Ser Val Thr Leu Phe Glu Ser
                 110                 115                 120

 Asp Leu Glu Ser Gly Lys Phe Ile Asp Ile Thr Asn Gln Glu Ile
                 125                 130                 135

 Ser Asp Leu Glu Glu Ile Gly Phe Gly Ser Lys Thr Arg Ser Ile
                 140                 145                 150

 His Val Lys Ser Gly Val Trp Val Ala Tyr Gln Gln Lys Phe Phe
                 155                 160                 165

 Cys Gly Glu Gln Tyr Ile Leu Glu Lys Gly Lys Tyr Lys Cys Phe
                 170                 175                 180

 Phe Asp Trp Gly Gly Ser Asn Asn Ile Ile Met Ser Ile Arg Pro
                 185                 190                 195

 Ile Gln Leu Glu Pro Leu Gly Ile Asn Glu Pro Pro His Leu Leu
                 200                 205                 210

 Lys Ala Phe Ser Lys Pro Gly Phe Gln Gly Glu Cys Ile Asp Phe
                 215                 220                 225

 Thr Glu Glu Thr Ser Asp Leu Thr Ser Leu Met Pro Cys Ser Phe
                 230                 235                 240

 Lys Val Leu Arg Gly Cys Trp Leu Leu Tyr Tyr Gln Glu Asp Met
                 245                 250                 255

 Phe Val Asn His Cys Val Leu Glu Glu Gly Leu Tyr Ala Asp Leu
                 260                 265                 270

 Thr Ser Cys Gly Cys Pro Ala Ser Lys Val Lys Ser Leu Lys Pro
                 275                 280                 285

 Ile Asp Tyr Val Phe Glu Glu Pro Ser Ile Ser Leu Phe Ala Leu
                 290                 295                 300

 Glu His Cys Glu Gly Arg Glu Leu His Leu Glu Glu Ala Val Asn
                 305                 310                 315

 Ser Val Leu Asn Lys Asp Leu His Phe Tyr Thr Gln Ser Val Trp
                 320                 325                 330

 Val Lys Ser Gly Leu Trp Ile Ala Tyr Glu Gly Ser Asn Phe Leu
                 335                 340                 345

 Gly Arg Gln Ile Leu Leu Arg Pro Asn Glu Ile Pro Asn Trp Thr
                 350                 355                 360

 Ala Phe Ser Arg Trp Lys Thr Ile Gly Ser Leu Arg Pro Met Lys
                 365                 370                 375

 Gln Pro Ala Val Tyr Ile Arg Ile Lys Asn Arg Ala Gln Gly Glu
                 380                 385                 390

 Tyr Leu Thr Val Thr Gly Ser Leu Ala Asp Thr Arg Ala Thr Ser
                 395                 400                 405

 Val Cys Ile Ser Pro Tyr Ser Gly Lys Asn Thr Gln Ile Trp Tyr
                 410                 415                 420

 Tyr Cys Arg Gly Leu Phe Lys Ser Lys Ala Ser Asp Thr Cys Leu
                 425                 430                 435

 Asp Val Ile Gly Gly Arg Asp Thr Pro Gly Ala Lys Val Ala Leu
                 440                 445                 450

 Trp Thr Glu His Gly Gln Phe Arg Gln Lys Trp Arg Leu Asn Lys
                 455                 460                 465

 Asn Gly Thr Ile Ser Ser Tyr Leu Ser Asp Gln Leu Val Leu Asp
                 470                 475                 480

 Val Lys Gly Gly Asn Tyr Cys Asp Lys Thr His Val Ile Val Asn
                 485                 490                 495

 Gln Pro Leu Glu Gly Glu Glu Thr Gln Lys Trp Asp Ile Glu Ile
                 500                 505                 510

 Leu


<210> 2749
<211> 2221
<212> DNA
<213> Homo sapien

<400> 2749
 acaccggtga cgagcgcacg gaaagtttgg aggcttagca aggagggtgg 50

 tgccggcctc cgcccggtgg tggcagaact gcctgtgcga gcacggcttc 100

 cacgtgggct gcgccgccgg gcgtcatgtc gggcctaaga gacacgctct 150

 acagctgtga aatctgaagt tcaggtttgc atttccttac tgctttgtct 200

 tgaagacaga acgatgccaa agaaagcaaa gcctacaggg agtgggaagg 250

 aagaggggcc ggctccctgt aagcagatga agttagaagc agctgggggg 300

 ccttcagctt taaactttga cagtcccagt agtctctttg aaagtttaat 350

 ctcgcccatc aagacagaga cttttttcaa ggaattctgg gagcagaagc 400

 cccttctcat tcagagagat gaccctgcac tggccacata ctatgggtcc 450

 ctgttcaagc taacagatct gaagagtctg tgcagccggg ggatgtacta 500

 tggaagagat gtgaatgtct gccggtgtgt caatgggaag aagaaggttt 550

 taaataaaga tggcaaagca cactttcttc agctgagaaa agattttgat 600

 cagaaaaggg caacgattca gtttcaccaa cctcagagat ttaaggatga 650

 gctttggagg atccaggaga agctggaatg ttactttggc tccttggttg 700

 gctcgaatgt gtacataact cccgcaggat ctcagggcct gccgccccat 750

 tatgatgatg tcgaggtttt catcctgcag ctggagggag agaaacactg 800

 gcgcctctac caccccactg tgcccctggc acgagagtac agcgtggagg 850

 ccgaggaaag gatcggcagg ccggtgcatg agtttatgct gaagccgggt 900

 gatttgttgt actttcccag aggaaccatt catcaagcgg acactcctgc 950

 ggggctggcc cactcgactc acgtgaccat cagcacctac cagaacaatt 1000

 catggggaga tttccttttg gataccatct cggggcttgt atttgatact 1050

 gcaaaggaag acgtggagtt acggaccggc ataccccggc agctgctcct 1100

 ggtggaatcc acaactgttg ctacaagacg attaagtggc ttcctgagga 1150

 cacttgcaga ccggctggag ggcaccaaag aactgctttc ctcagacatg 1200

 aagaaggatt ttattatgca cagactcccc ccttactctg cgggagatgg 1250

 ggcagagctg tcaacaccag gtggaaagtt accgaggctg gacagtgtag 1300

 tgagactgca gtttaaagac cacattgtcc tcacagtact gccggatcaa 1350

 gatcaatctg atgaagctca agaaaagatg gtgtacatct atcattcctt 1400

 aaagaatagt agagagacac acatgatggg aaatgaggag gaaacagagt 1450

 ttcatggact tcgcttccct ttgtcacatt tggatgcact gaagcaaatt 1500

 tggaatagtc cagctatttc tgtcaaggac ctgaaactta ctacagatga 1550

 ggaaaaggaa agcctggtat tatccctctg gacagaatgt ttaattcaag 1600

 tagtctagtg cctttgcaga atcaaatgcc tactatttta tatgcatata 1650

 ttaaaagaaa agcaaagacc tgagccgagg agaggatgaa ttcaagtttc 1700

 cttacctgcg tatctactaa caaacatgag acctccctgt tacaggtggt 1750

 cagttggcca aatgtactaa cgggcacatg aaagaaagaa cagcaaatta 1800

 ccaagtgtct cagaaaatga caaaaccata ttttgacaag tttatttaat 1850

 ccagtgtggt agaaaaggca caattccaat gtatcattta gaattgaatg 1900

 tcattaacct ggctttgttc tttggaagaa acaacttctt taaagagctt 1950

 ctttggctct agaaaaattt caaacaatta aaataagaaa aaattttaaa 2000

 ctggtttttt ataatgaaaa tatacatacc tttgtgtata gacaagccca 2050

 tgcccattaa aataaagtta tcctgtacca tacatttatt aaataatact 2100

 tccccacaga tgagaggcac gcaacactat ggacaaaagg gagttacgag 2150

 gctgttaaag atgggcaaag ctggatgagg ggaaaaacca gtatttaagt 2200

 ctataaaata ctcaatgtgg c 2221

<210> 2750
<211> 464
<212> PRT
<213> Homo sapien

<400> 2750
 Met Pro Lys Lys Ala Lys Pro Thr Gly Ser Gly Lys Glu Glu Gly
   1               5                  10                  15

 Pro Ala Pro Cys Lys Gln Met Lys Leu Glu Ala Ala Gly Gly Pro
                  20                  25                  30

 Ser Ala Leu Asn Phe Asp Ser Pro Ser Ser Leu Phe Glu Ser Leu
                  35                  40                  45

 Ile Ser Pro Ile Lys Thr Glu Thr Phe Phe Lys Glu Phe Trp Glu
                  50                  55                  60

 Gln Lys Pro Leu Leu Ile Gln Arg Asp Asp Pro Ala Leu Ala Thr
                  65                  70                  75

 Tyr Tyr Gly Ser Leu Phe Lys Leu Thr Asp Leu Lys Ser Leu Cys
                  80                  85                  90

 Ser Arg Gly Met Tyr Tyr Gly Arg Asp Val Asn Val Cys Arg Cys
                  95                 100                 105

 Val Asn Gly Lys Lys Lys Val Leu Asn Lys Asp Gly Lys Ala His
                 110                 115                 120

 Phe Leu Gln Leu Arg Lys Asp Phe Asp Gln Lys Arg Ala Thr Ile
                 125                 130                 135

 Gln Phe His Gln Pro Gln Arg Phe Lys Asp Glu Leu Trp Arg Ile
                 140                 145                 150

 Gln Glu Lys Leu Glu Cys Tyr Phe Gly Ser Leu Val Gly Ser Asn
                 155                 160                 165

 Val Tyr Ile Thr Pro Ala Gly Ser Gln Gly Leu Pro Pro His Tyr
                 170                 175                 180

 Asp Asp Val Glu Val Phe Ile Leu Gln Leu Glu Gly Glu Lys His
                 185                 190                 195

 Trp Arg Leu Tyr His Pro Thr Val Pro Leu Ala Arg Glu Tyr Ser
                 200                 205                 210

 Val Glu Ala Glu Glu Arg Ile Gly Arg Pro Val His Glu Phe Met
                 215                 220                 225

 Leu Lys Pro Gly Asp Leu Leu Tyr Phe Pro Arg Gly Thr Ile His
                 230                 235                 240

 Gln Ala Asp Thr Pro Ala Gly Leu Ala His Ser Thr His Val Thr
                 245                 250                 255

 Ile Ser Thr Tyr Gln Asn Asn Ser Trp Gly Asp Phe Leu Leu Asp
                 260                 265                 270

 Thr Ile Ser Gly Leu Val Phe Asp Thr Ala Lys Glu Asp Val Glu
                 275                 280                 285

 Leu Arg Thr Gly Ile Pro Arg Gln Leu Leu Leu Val Glu Ser Thr
                 290                 295                 300

 Thr Val Ala Thr Arg Arg Leu Ser Gly Phe Leu Arg Thr Leu Ala
                 305                 310                 315

 Asp Arg Leu Glu Gly Thr Lys Glu Leu Leu Ser Ser Asp Met Lys
                 320                 325                 330

 Lys Asp Phe Ile Met His Arg Leu Pro Pro Tyr Ser Ala Gly Asp
                 335                 340                 345

 Gly Ala Glu Leu Ser Thr Pro Gly Gly Lys Leu Pro Arg Leu Asp
                 350                 355                 360

 Ser Val Val Arg Leu Gln Phe Lys Asp His Ile Val Leu Thr Val
                 365                 370                 375

 Leu Pro Asp Gln Asp Gln Ser Asp Glu Ala Gln Glu Lys Met Val
                 380                 385                 390

 Tyr Ile Tyr His Ser Leu Lys Asn Ser Arg Glu Thr His Met Met
                 395                 400                 405

 Gly Asn Glu Glu Glu Thr Glu Phe His Gly Leu Arg Phe Pro Leu
                 410                 415                 420

 Ser His Leu Asp Ala Leu Lys Gln Ile Trp Asn Ser Pro Ala Ile
                 425                 430                 435

 Ser Val Lys Asp Leu Lys Leu Thr Thr Asp Glu Glu Lys Glu Ser
                 440                 445                 450

 Leu Val Leu Ser Leu Trp Thr Glu Cys Leu Ile Gln Val Val
                 455                 460

<210> 2751
<211> 1030
<212> DNA
<213> Homo sapien

<400> 2751
 agatgtaaac caatttcagg ccacaactcc cttttctggt acagacagac 50

 catgatgcgg ggactggagt tgctcattta ctttaacaac aacgttccga 100

 tagatgattc agggatgccc gaggatcgat tctcagctaa gatgcctaat 150

 gcatcattct ccactctgaa gatccagccc tcagaaccca gggactcagc 200

 tgtgtacttc tgtgccagca gtttctcgac ctgttcggct aactatggct 250

 acaccttcgg ttcggggacc aggttaaccg ttgtagagga cctgaacaag 300

 gtgttcccac ccgaggtcgc tgtgtttgag ccatcagaag cagagatctc 350

 ccacacccaa aaggccacac tggtgtgcct ggccacaggc ttcttccccg 400

 accacgtgga gctgagctgg tgggtgaatg ggaaggaggt gcacagtggg 450

 gtcagcacag acccgcagcc cctcaaggag cagcccgccc tcaatgactc 500

 cagatactgc ctgagcagcc gcctgagggt ctcggccacc ttctggcaga 550

 acccccgcaa ccacttccgc tgtcaagtcc agttctacgg gctctcggag 600

 aatgacgagt ggacccagga tagggccaaa cccgtcaccc agatcgtcag 650

 cgccgaggcc tggggtagag cagactgtgg ctttacctcg gtgtcctacc 700

 agcaaggggt cctgtctgcc accatcctct atgagatcct gctagggaag 750

 gccaccctgt atgctgtgct ggtcagcgcc cttgtgttga tggccatggt 800

 caagagaaag gatttctgaa ggcagccctg gaagtggagt taggagcttc 850

 taacccgtca tggtttcaat acacattctt cttttgccag cgcttctgaa 900

 gagctgctct cacctctctg catcccaata gatatccccc tatgtgcatg 950

 cacacctgca cactcacggc tgaaatctcc ctaacccagg gggaccttag 1000

 catgcctaag tgactaaacc aataaaaatg 1030

<210> 2752
<211> 1698
<212> DNA
<213> Homo sapien

<400> 2752
 gttccgagga agccagaccc ggagccgtgg cctgccgggc cggcgacatg 50

 gatcccctgt tccagcaaac gcacaagcag gtccacgaga tccagtcttg 100

 catgggacgc ctggagacgg cagacaagca gtctgtgcac atagtagaaa 150

 acgaaatcca agcaagcata gaccagatat tcagccgtct agaacgtctg 200

 gagattttgt ccagcaagga gccccctaac aaaaggcaaa atgccagact 250

 tcgggttgac cagttaaagt atgatgtcca gcacctgcag actgcgctca 300

 gaaacttcca gcatcggcgc catgcaaggg agcagcagga gagacagcga 350

 gaagagcttc tgtctcgaac cttcaccact aacgggactc agaagaagat 400

 ccttgacatt gccaacatgc tgggcttgtc caacacagtg atgcggctca 450

 tcgagaagcg ggctttccag gacaagtact ttatgatagg tgggatgctg 500

 ctgacctgtg tggtcatgtt cctcgtggtg cagtacctga catgagccag 550

 ccacgctcag tggctgaaca gcattcccac agcctgcaag tgtgtgtgtg 600

 tgtgaaagag agaggggggc ccagaggccg ccttttgaaa tgtttgcctg 650

 tctgaactgt gaagacactt gggagtgatt gtggtctaat ttccaacctg 700

 ctctgttttc tgtgacatct tggaggggga gctagtgcca ccaccatgcg 750

 cggtgcttag gaaatgaaag aagtcccggg tctgtctctc tcactctcgc 800

 tctcactggg ggagggaaag aatggctttg gtggctttgt tcacacagct 850

 gatgcgtgcc ctgggaaggt gtccacagtg agccctgtgt gcaggactgt 900

 ccacacgggt tcacaccttg tcaaccatca ggcctttctg gctcctgata 950

 gggtggagca aaagtggaaa ggaaaggaaa gaggcctttt ctcacagcca 1000

 ttatattaaa tagtaggtcg attcacatcc tcgtgctcct ggccaccctc 1050

 tagtggaggc gggggtgaat tcttaggtcg agctgatgca agaaactctg 1100

 gtagccagcc tctgtgacct tgtacatgag tttggtgtgc ctattgtgat 1150

 ttaaaacagg tgggttatca agaggaactt gagatctctt tattacatgg 1200

 acatttactt cagggggacc actgtaagaa aagccaaact ccaagaccaa 1250

 gtaagttaga ggagtcttga ttttttagac ttcactgcgg agttctgtac 1300

 accctttgcc ctgatgaatt tgaatgggtt tgatttgcaa atttggattt 1350

 acacccattg ttttggaagc acatcagctg aataaagttg aggtttattt 1400

 tatttagaaa atcacatttt gtaaaagaat tcgatattca tttttataac 1450

 taatggcccc ctttttttat gtttctaggc cagagattct caaacactgc 1500

 tccatggcca ggggctgggc tggctgcttc agaagcagtg gggaagcttt 1550

 ttaaaattac atattcctgg ggcctacccc agatctgaat tagaaccttt 1600

 tttaaatctc taaggtgatt ctgatgtgtg tattttggaa ccactgtctc 1650

 ctagacagaa agcttctgtc tcaaagatga tcacattggt gtaaagag 1698

<210> 2753
<211> 180
<212> PRT
<213> Homo sapien

<400> 2753
 Ser Glu Glu Ala Arg Pro Gly Ala Val Ala Cys Arg Ala Gly Asp
   1               5                  10                  15

 Met Asp Pro Leu Phe Gln Gln Thr His Lys Gln Val His Glu Ile
                  20                  25                  30

 Gln Ser Cys Met Gly Arg Leu Glu Thr Ala Asp Lys Gln Ser Val
                  35                  40                  45

 His Ile Val Glu Asn Glu Ile Gln Ala Ser Ile Asp Gln Ile Phe
                  50                  55                  60

 Ser Arg Leu Glu Arg Leu Glu Ile Leu Ser Ser Lys Glu Pro Pro
                  65                  70                  75

 Asn Lys Arg Gln Asn Ala Arg Leu Arg Val Asp Gln Leu Lys Tyr
                  80                  85                  90

 Asp Val Gln His Leu Gln Thr Ala Leu Arg Asn Phe Gln His Arg
                  95                 100                 105

 Arg His Ala Arg Glu Gln Gln Glu Arg Gln Arg Glu Glu Leu Leu
                 110                 115                 120

 Ser Arg Thr Phe Thr Thr Asn Gly Thr Gln Lys Lys Ile Leu Asp
                 125                 130                 135

 Ile Ala Asn Met Leu Gly Leu Ser Asn Thr Val Met Arg Leu Ile
                 140                 145                 150

 Glu Lys Arg Ala Phe Gln Asp Lys Tyr Phe Met Ile Gly Gly Met
                 155                 160                 165

 Leu Leu Thr Cys Val Val Met Phe Leu Val Val Gln Tyr Leu Thr
                 170                 175                 180

<210> 2754
<211> 2821
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2794, 2802, 2808-2813, 2816, 2818
<223> Unknown base

<400> 2754
 cgggatactt gaactgcaag aacagccgcc gctccagcgg gctgctcgct 50

 gcatctctgg gcgtctttgg ctcgccacgc tgggcagtgc ctgcctgcgc 100

 ctttcgcaac ctcctcggcc ctgcgtggtc tcgagctggg tgagcgagcg 150

 ggcgggctgg taggctggcc tgggctgcga ccggcggcta cgactattct 200

 ttggccgggt cggtgcgagt ggtcggctgg gcagagtgca cgctgcttgg 250

 cgccgcaggc tgatcccgcc gtccactccc gggagcagtg atgttgggca 300

 actctgcgcc ggggcctgcg acccgcgagg cgggctcggc gctgctagca 350

 ttgcagcaga cggcgctcca agaggaccag gagaatatca acccggaaaa 400

 ggcagcgccc gtccaacaac cgcggacccg ggccgcgctg gcggtactga 450

 agtccgggaa cccgcggggt ctagcgcagc agcagaggcc gaagacgaga 500

 cgggttgcac cccttaagga tcttcctgta aaatgatgag catgtcaccg 550

 ttcctccttg gaaagcaaac agtaaacagc ctgcgttcac cattcatgtg 600

 gatgaagcag aaaaagaagc tcagaagaag ccagctgaat ctcaaaaaat 650

 agagcgtgaa gatgccctgg cttttaattc agccattagt ttacctggac 700

 ccagaaaacc attggtccct cttgattatc caatggatgg tagttttgag 750

 tcaccacata ctatggacat gtcaattgta ttagaagatg aaaagccagt 800

 gagtgttaat gaagtaccag actaccatga ggatattcac acatacctta 850

 gggaaatgga ggttaaatgt aaacctaaag tgggttacat gaagaaacag 900

 ccagacatca ctaacagtat gagagctatc ctcgtggact ggttagttga 950

 agtaggagaa gaatataaac tacagaatga gaccctgcat ttggctgtga 1000

 actacattga taggttcctg tcttccatgt cagtgctgag aggaaaactt 1050

 cagcttgtgg gcactgctgc tatgctgtta gcctcaaagt ttgaagaaat 1100

 atacccccca gaagtagcag agtttgtgta cattacagat gatacctaca 1150

 ccaagaaaca agttctgaga atggagcatc tagttttgaa agtccttact 1200

 tttgacttag ctgctccaac agtaaatcag tttcttaccc aatactttct 1250

 gcatcagcag cctgcaaact gcaaagttga aagtttagca atgtttttgg 1300

 gagaattaag tttgatagat gctgacccat acctcaagta tttgccatca 1350

 gttattgctg gagctgcctt tcatttagca ctctacacag tcacgggaca 1400

 aagctggcct gaatcattaa tacgaaagac tggatatacc ctggaaagtc 1450

 ttaagccttg tctcatggac cttcaccaga cctacctcaa agcaccacag 1500

 catgcacaac agtcaataag agaaaagtac aaaaattcaa agtatcatgg 1550

 tgtttctctc ctcaacccac cagagacact aaatctgtaa caatgaaaga 1600

 ctgcctttgt tttctaagat gtaaatcact caaagtatat ggtgtacagt 1650

 ttttaactta ggttttaatt ttacaatcat ttctgaatac agaagttgtg 1700

 gccaagtaca aattatggta tctattactt tttaaatggt tttaatttgt 1750

 atatcttttg tatatgtatc tgtcttagat atttggctaa ttttaagtgg 1800

 ttttgttaaa gtattaatga tgccagctgt caggataata aattgatttg 1850

 gaaaactttg caagtcaaat ttaacttctt caggattttg cttagtaaag 1900

 aagtttactt ggtttactat ataatgggaa gtgaaaagcc ttcctctaaa 1950

 attaaagtag gtttaggaaa acagaccctc aaattctgac attcattttc 2000

 ctaagcaact ggatcaattt gctgacttgg gcataatcta atctaagcat 2050

 atctgaatac agtattcaga gatagataca gtagagattc cccagacttt 2100

 ttcgctcttt gtaaaacctg tttgtttagg ttttgcgagg taaactcaac 2150

 agaggttggg agtggaagag ggtgggaagc ttatatgcaa attaacagac 2200

 gagaaatgct ccagaaggtt tattatttta aagcacatta aaaacaaaaa 2250

 actattttta aaatcctgct agattttata atggatttgt gaataaaaaa 2300

 tacccagggt tctcagaatg gaataaatat cccttttaat agttatatat 2350

 acagatatac aactgttagc tttaattggc agctctcttc ttttttcttc 2400

 ttttcactgg ctttttactt ggtgcttttt cttgttttgc actggtggtc 2450

 tgtgttctgt gaataaagca aagtaagaat ttactaagag tatgttaagt 2500

 tttggattat tgaaataaga ggcatttctt agttttccag taggatctaa 2550

 aatgtgtcag ctatgagtaa gactggcatc caagaagttt atattataga 2600

 tttaggtcct aatttttata aatcacaagg taaaaaaatc acagaacaga 2650

 tggatctcta atgaaaaagg gatgtctttt tgtttatagt catgtggcaa 2700

 gatgagagta aaaccagaga gcaaacctct ataagtgttg agtatatgta 2750

 tacatttgaa ataaaccaga aatttgttac cttaaaaaaa aaanaacttc 2800

 anaatacnnn nnnaancnca c 2821

<210> 2755
<211> 285
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2794, 2802, 2808-2813, 2816, 2818
<223> Unknown amino acid

<400> 2755
 Met Asp Gly Ser Phe Glu Ser Pro His Thr Met Asp Met Ser Ile
   1               5                  10                  15

 Val Leu Glu Asp Glu Lys Pro Val Ser Val Asn Glu Val Pro Asp
                  20                  25                  30

 Tyr His Glu Asp Ile His Thr Tyr Leu Arg Glu Met Glu Val Lys
                  35                  40                  45

 Cys Lys Pro Lys Val Gly Tyr Met Lys Lys Gln Pro Asp Ile Thr
                  50                  55                  60

 Asn Ser Met Arg Ala Ile Leu Val Asp Trp Leu Val Glu Val Gly
                  65                  70                  75

 Glu Glu Tyr Lys Leu Gln Asn Glu Thr Leu His Leu Ala Val Asn
                  80                  85                  90

 Tyr Ile Asp Arg Phe Leu Ser Ser Met Ser Val Leu Arg Gly Lys
                  95                 100                 105

 Leu Gln Leu Val Gly Thr Ala Ala Met Leu Leu Ala Ser Lys Phe
                 110                 115                 120

 Glu Glu Ile Tyr Pro Pro Glu Val Ala Glu Phe Val Tyr Ile Thr
                 125                 130                 135

 Asp Asp Thr Tyr Thr Lys Lys Gln Val Leu Arg Met Glu His Leu
                 140                 145                 150

 Val Leu Lys Val Leu Thr Phe Asp Leu Ala Ala Pro Thr Val Asn
                 155                 160                 165

 Gln Phe Leu Thr Gln Tyr Phe Leu His Gln Gln Pro Ala Asn Cys
                 170                 175                 180

 Lys Val Glu Ser Leu Ala Met Phe Leu Gly Glu Leu Ser Leu Ile
                 185                 190                 195

 Asp Ala Asp Pro Tyr Leu Lys Tyr Leu Pro Ser Val Ile Ala Gly
                 200                 205                 210

 Ala Ala Phe His Leu Ala Leu Tyr Thr Val Thr Gly Gln Ser Trp
                 215                 220                 225

 Pro Glu Ser Leu Ile Arg Lys Thr Gly Tyr Thr Leu Glu Ser Leu
                 230                 235                 240

 Lys Pro Cys Leu Met Asp Leu His Gln Thr Tyr Leu Lys Ala Pro
                 245                 250                 255

 Gln His Ala Gln Gln Ser Ile Arg Glu Lys Tyr Lys Asn Ser Lys
                 260                 265                 270

 Tyr His Gly Val Ser Leu Leu Asn Pro Pro Glu Thr Leu Asn Leu
                 275                 280                 285

<210> 2756
<211> 6550
<212> DNA
<213> Homo sapien

<400> 2756
 tcccggaagg caaatggctg gcgtggaagc acaacccgct ttcactcttc 50

 gaatttgtgc ttagctcttt tcttgtacct tgcgactcgt gaccaacatg 100

 ctgtgatgtg tgccgaggga ggaattggtc agctacacaa cctggatctt 150

 accacagttt ggatatgact gaggctctcc aatgggccag atatcactgg 200

 cgacggctga tcagaggtgc aaccagggat gatgattcag ggccatacaa 250

 ctattcctcg ttgctcgcct gtgggcgcaa gtcctctcag acccctaaac 300

 tgtcaggaag gcaccggatt gttgttcccc acatccagcc cttcaaggat 350

 gagtatgaga agttctccgg agcctatgtg aacaatcgaa tacgaacaac 400

 aaagtacaca cttctgaatt ttgtgccaag aaatttattt gaacaatttc 450

 acagagctgc caatttatat ttcctgttcc tagttgtcct gaactgggta 500

 cctttggtag aagccttcca aaaggaaatc accatgttgc ctctggtggt 550

 ggtccttaca attatcgcaa ttaaagatgg cctggaaggt tatcggaaat 600

 acaaaattga caaacagatc aataatttaa taactaaagt ttatagtagg 650

 aaagagaaaa aatacattga ccgatgctgg aaagacgtta ctgttgggga 700

 ctttattcgc ctctcctgca acgaggtcat ccctgcagac atggtactac 750

 tcttttccac tgatccagat ggaatctgtc acattgagac ttctggtctt 800

 gatggagaga gcaatttaaa acagaggcag gtggttcggg gatatgcaga 850

 acaggactct gaagttgatc ctgagaagtt ttccagtagg atagaatgtg 900

 aaagcccaaa caatgacctc agcagattcc gaggcttcct agaacattcc 950

 aacaaagaac gcgtgggtct cagtaaagaa aatttgttgc ttagaggatg 1000

 caccattaga aacacagagg ctgttgtggg cattgtggtt tatgcaggcc 1050

 atgaaaccaa agcaatgctg aacaacagtg ggccacggta taagcgcagc 1100

 aaattagaaa gaagagcaaa cacagatgtc ctctggtgtg tcatgcttct 1150

 ggtcataatg tgcttaactg gcgcagtagg tcatggaatc tggctgagca 1200

 ggtatgaaaa gatgcatttt ttcaatgttc ccgagcctga tggacatatc 1250

 atatcaccac tgttggcagg attttatatg ttttggacca tgatcatttt 1300

 gttacaggtc ttgattccta tttctctcta tgtttccatc gaaattgtga 1350

 agcttggaca aatatatttc attcaaagtg atgtggattt ctacaatgaa 1400

 aaaatggatt ctattgttca gtgccgagcc ctgaacatcg ccgaggatct 1450

 gggacagatt cagtacctct tttccgataa gacaggaacc ctcactgaga 1500

 ataagatggt ttttcgaaga tgtagtgtgg caggatttga ttactgccat 1550

 gaagaaaatg ccaggaggtt ggagtcctat caggaagctg tctctgaaga 1600

 tgaagatttt atagacacag tcagtggttc cctcagcaat atggcaaaac 1650

 cgagagcccc cagctgcagg acagttcata atgggccttt gggaaataag 1700

 ccctcaaatc atcttgctgg gagctctttt actctaggaa gtggagaagg 1750

 agccagtgaa gtgcctcatt ccagacaggc tgctttcagt agccccattg 1800

 aaacagacgt ggtaccagac accaggcttt tagacaaatt tagtcagatt 1850

 acacctcggc tctttatgcc actagatgag accatccaaa atccaccaat 1900

 ggaaactttg tacattatcg actttttcat tgcattggca atttgcaaca 1950

 cagtagtggt ttctgctcct aaccaacccc gacaaaagat cagacaccct 2000

 tcactggggg ggttgcccat taagtctttg gaagagatta aaagtctttt 2050

 ccagagatgg tctgtccgaa gatcaagttc tccatcgctt aacagtggga 2100

 aagagccatc ttctggagtt ccaaacgcct ttgtgagcag actccctctc 2150

 tttagtcgaa tgaaaccagc ttcacctgtg gaggaagagg tctcccaggt 2200

 gtgtgagagc ccccagtgct ccagtagctc agcttgctgc acagaaacag 2250

 agaaacaaca cggtgatgca ggcctcctga atggcaaggc agagtccctc 2300

 cctggacagc cattggcctg caacctgtgt tatgaggccg agagcccaga 2350

 cgaagcggcc ttagtgtatg ccgccagggc ttaccaatgc actttacggt 2400

 ctcggacacc agagcaggtc atggtggact ttgctgcttt gggaccatta 2450

 acatttcaac tcctacacat cctgcccttt gactcagtaa gaaaaagaat 2500

 gtctgttgtg gtccgacacc ctctttccaa tcaagttgtg gtgtatacga 2550

 aaggcgctga ttctgtgatc atggagttac tgtcggtggc ttccccagat 2600

 ggagcaagtc tggagaaaca acagatgata gtaagggaga aaacccagaa 2650

 gcacttggat gactatgcca aacaaggcct tcgtacttta tgtatagcaa 2700

 agaaggtcat gagtgacact gaatatgcag agtggctgag gaatcatttt 2750

 ttagctgaaa ccagcattga caacagggaa gaattactac ttgaatctgc 2800

 catgaggttg gagaacaaac ttacattact tggtgctact ggcattgaag 2850

 accgtctgca ggagggagtc cctgaatcta tagaagctct tcacaaagcg 2900

 ggcatcaaga tctggatgct gacaggggac aagcaggaga cagctgtcaa 2950

 catagcttat gcatgcaaac tactggagcc agatgacaag ctttttatcc 3000

 tcaataccca aagtaaagat gcctgtggga tgctgatgag cacaattttg 3050

 aaagaacttc agaagaaaac tcaagccctg ccagagcaag tgtcattaag 3100

 tgaagattta cttcagcctc ctgtcccccg ggactcaggg ttacgagctg 3150

 gactcattat cactgggagg accctggagt ttgccctgca agaaagtctg 3200

 caaaagcagt tcctggaact gacatcttgg tgtcaagctg tggtctgctg 3250

 ccgagccaca ccgctgcaga aaagtgaagt ggtgaaattg gtccgcagcc 3300

 atctccaggt gatgaccctt gctattggtg atggtgccaa tgatgttagc 3350

 atgatacaag tggcagacat tgggataggg gtctcaggtc aagaaggcat 3400

 gcaggctgtg atggccagtg actttgccgt ttatcagttc aaacatctca 3450

 gcaagctcct tcttgtccat ggacactggt gttatacacg gctttccaac 3500

 atgattctct attttttcta taagaatgtg gcctatgtga acctcctttt 3550

 ctggtaccag ttcttttgtg gattttcagg gacatccatg actgattact 3600

 gggttttgat cttcttcaac ctcctcttca catctgcccc tcctgtcatt 3650

 tatggtgttt tggagaaaga tgtgtctgca gagaccctca tgcaactgcc 3700

 tgaactttac agaagtggtc agaaatcaga ggcatactta ccccatacct 3750

 tctggatcac cttattggat gctttttatc aaagcctggt ctgcttcttt 3800

 gtgccttatt ttacctacca gggctcagat actgacatct ttgcatttgg 3850

 aaaccccctg aacacagccg ctctgttcat cgttctcctc catctggtca 3900

 ttgaaagcaa gagtttgact tggattcact tgctggtcat cattggtagc 3950

 atcttgtctt attttttatt tgccatagtt tttggagcca tgtgtgtaac 4000

 ttgcaaccca ccatccaacc cttactggat tatgcaggag cacatgctgg 4050

 atccagtatt ctacttagtt tgtatcctca cgacgtccat tgctcttctg 4100

 cccaggtttg tatacagagt tcttcaggga tccctgtttc catctccaat 4150

 tctgagagct aagcactttg acagactaac tccagaggag aggactaaag 4200

 ctctcaagaa gtggagaggg gctggaaaga tgaatcaagt gacatcaaag 4250

 tatgctaacc aatcagctgg caagtcagga agaagaccca tgcctggccc 4300

 ttctgctgta tttgcaatga agtcagcaag ttcctgtgct attgagcaag 4350

 gaaacttatc tctgtgtgag actgctttag atcaaggcta ctctgaaact 4400

 aaggcctttg agatggctgg accctccaaa ggtaaagaaa gctagatacc 4450

 ctccttggag ttgcaagtat tctttcaagg ttggaagagg gattttgaag 4500

 aggtatctct ccaagcaaga atgacttgtt tttccataag ggacatgagc 4550

 attttactag gcttggaaga gctgacatga tgagcattat tgtatgtttg 4600

 tatatacatt tgtgatagag ggctagagtt tgacctagag agagtttaag 4650

 gaagtgaaat atttaattca gaaccaaatg cttttgtaaa actttttgga 4700

 ttttgtaaaa gcattttcat tctcttagaa attcaagtat tttcaagggg 4750

 agtcatttga gatatattta ttttactagg agatcttata ttctagggaa 4800

 atgctttaaa tggtcaggct ccagtcggaa tttttttaag aaaaaagtag 4850

 tttttaatac attggttagg actcagagga aatacggaaa aaacattgta 4900

 gatggttaat ttacagataa aatcccaaga gccttttaaa caacaaggta 4950

 cctaaaatag ggtataatta tactgcttaa aatacagtta gtgcctatta 5000

 atagcttttt atttcctatg ggaagatgct tttggtcttc tggctgaaga 5050

 tgtaggcata cctctcactc atttcaatgt tttcctgagg tggagccttc 5100

 attggaaagg ggaaagaggg attctagggt ttcatcaggg accaggaatg 5150

 cattcctctg tcaggttcca atcaagagaa gaccttttat gagatctgcc 5200

 tctgtataga tgttgtcagt taggaaactg aagccatagg tcaggcagac 5250

 atcagctcag cctgtggccc attgggtgat ttcctgtatt ttaaaactga 5300

 cagtagcctg atcaaagtga tacaatcaat ttcaaaacaa tcttccagag 5350

 accacttgaa ggttcatagt ttttacaata ccctgagact tttcaggtgt 5400

 tggagcctct aaaatatgag atataaacag aaactaatac aagttgttct 5450

 ctggaggttt ctatgaggtt cttagaaaaa tttggtttta aaatcatttg 5500

 aggacaggaa tgtctatagc aagtttactc ctattgcgaa tcatgtatgc 5550

 tggctttagt tgtaacaaac gattttattc taagtaaggc caggtgctac 5600

 tataaaatca tatattcctg ttgaagttct tttgaagtcc tatctctatt 5650

 tattatattt gaaagttgtc agccaccagt catccagaat ttccttcctg 5700

 aatctccatg ctcatatgca atgtctacat caaggtcttc ttaatgacta 5750

 ttattctcag ggtttagttt tctaccttct gcctactatt ttggtctgac 5800

 atttttgtag ccttctgtta ttattggaaa tagtctctta cataagctga 5850

 tttcgagaac tttcaaaatc tcacatagct aatggaagtt gctttctgct 5900

 ttcttatgac tgtttttata aataaactgt ttcataaata atgtatactg 5950

 gaaaattgtc atcactcttg taaacatttg ccaaatccaa ctgtaattag 6000

 taccagaact tagaaggaaa gtcacaaagc atgcctttta ccagaatatt 6050

 gctttgcctt ttcttatatg gaaaatcact gatgtcatat catttattat 6100

 cctcacagca gctggcattc attccctgaa atcgtcgtct cctgataaac 6150

 aataatttag agatatgttc acttgtaaat aaaaaggtta gaatctaagg 6200

 acaaagaatg atccaaaaat actaaggaaa aagaacaatt ttcaattttc 6250

 agaaatgaat tatctgtaca tatgaataga ggaaaatact gagtgctaat 6300

 gttacagggc cacaatctca tatccacaat tccaaaatct ccaaacctct 6350

 gaaaactgaa atatttttca taaattaggc gtaaattcta tgccctgaac 6400

 aaatgtaaag ctatttatgt actttgctta atgtaatcat tcatatactt 6450

 tgctacaaaa atattaatat atttcattac tgaatgctaa actgtatttc 6500

 tttttaaaat ttggaaaatt tttaattctg aaacacaatc tagaccttag 6550

<210> 2757
<211> 1426
<212> PRT
<213> Homo sapien

<400> 2757
 Met Thr Glu Ala Leu Gln Trp Ala Arg Tyr His Trp Arg Arg Leu
   1               5                  10                  15

 Ile Arg Gly Ala Thr Arg Asp Asp Asp Ser Gly Pro Tyr Asn Tyr
                  20                  25                  30

 Ser Ser Leu Leu Ala Cys Gly Arg Lys Ser Ser Gln Thr Pro Lys
                  35                  40                  45

 Leu Ser Gly Arg His Arg Ile Val Val Pro His Ile Gln Pro Phe
                  50                  55                  60

 Lys Asp Glu Tyr Glu Lys Phe Ser Gly Ala Tyr Val Asn Asn Arg
                  65                  70                  75

 Ile Arg Thr Thr Lys Tyr Thr Leu Leu Asn Phe Val Pro Arg Asn
                  80                  85                  90

 Leu Phe Glu Gln Phe His Arg Ala Ala Asn Leu Tyr Phe Leu Phe
                  95                 100                 105

 Leu Val Val Leu Asn Trp Val Pro Leu Val Glu Ala Phe Gln Lys
                 110                 115                 120

 Glu Ile Thr Met Leu Pro Leu Val Val Val Leu Thr Ile Ile Ala
                 125                 130                 135

 Ile Lys Asp Gly Leu Glu Gly Tyr Arg Lys Tyr Lys Ile Asp Lys
                 140                 145                 150

 Gln Ile Asn Asn Leu Ile Thr Lys Val Tyr Ser Arg Lys Glu Lys
                 155                 160                 165

 Lys Tyr Ile Asp Arg Cys Trp Lys Asp Val Thr Val Gly Asp Phe
                 170                 175                 180

 Ile Arg Leu Ser Cys Asn Glu Val Ile Pro Ala Asp Met Val Leu
                 185                 190                 195

 Leu Phe Ser Thr Asp Pro Asp Gly Ile Cys His Ile Glu Thr Ser
                 200                 205                 210

 Gly Leu Asp Gly Glu Ser Asn Leu Lys Gln Arg Gln Val Val Arg
                 215                 220                 225

 Gly Tyr Ala Glu Gln Asp Ser Glu Val Asp Pro Glu Lys Phe Ser
                 230                 235                 240

 Ser Arg Ile Glu Cys Glu Ser Pro Asn Asn Asp Leu Ser Arg Phe
                 245                 250                 255

 Arg Gly Phe Leu Glu His Ser Asn Lys Glu Arg Val Gly Leu Ser
                 260                 265                 270

 Lys Glu Asn Leu Leu Leu Arg Gly Cys Thr Ile Arg Asn Thr Glu
                 275                 280                 285

 Ala Val Val Gly Ile Val Val Tyr Ala Gly His Glu Thr Lys Ala
                 290                 295                 300

 Met Leu Asn Asn Ser Gly Pro Arg Tyr Lys Arg Ser Lys Leu Glu
                 305                 310                 315

 Arg Arg Ala Asn Thr Asp Val Leu Trp Cys Val Met Leu Leu Val
                 320                 325                 330

 Ile Met Cys Leu Thr Gly Ala Val Gly His Gly Ile Trp Leu Ser
                 335                 340                 345

 Arg Tyr Glu Lys Met His Phe Phe Asn Val Pro Glu Pro Asp Gly
                 350                 355                 360

 His Ile Ile Ser Pro Leu Leu Ala Gly Phe Tyr Met Phe Trp Thr
                 365                 370                 375

 Met Ile Ile Leu Leu Gln Val Leu Ile Pro Ile Ser Leu Tyr Val
                 380                 385                 390

 Ser Ile Glu Ile Val Lys Leu Gly Gln Ile Tyr Phe Ile Gln Ser
                 395                 400                 405

 Asp Val Asp Phe Tyr Asn Glu Lys Met Asp Ser Ile Val Gln Cys
                 410                 415                 420

 Arg Ala Leu Asn Ile Ala Glu Asp Leu Gly Gln Ile Gln Tyr Leu
                 425                 430                 435

 Phe Ser Asp Lys Thr Gly Thr Leu Thr Glu Asn Lys Met Val Phe
                 440                 445                 450

 Arg Arg Cys Ser Val Ala Gly Phe Asp Tyr Cys His Glu Glu Asn
                 455                 460                 465

 Ala Arg Arg Leu Glu Ser Tyr Gln Glu Ala Val Ser Glu Asp Glu
                 470                 475                 480

 Asp Phe Ile Asp Thr Val Ser Gly Ser Leu Ser Asn Met Ala Lys
                 485                 490                 495

 Pro Arg Ala Pro Ser Cys Arg Thr Val His Asn Gly Pro Leu Gly
                 500                 505                 510

 Asn Lys Pro Ser Asn His Leu Ala Gly Ser Ser Phe Thr Leu Gly
                 515                 520                 525

 Ser Gly Glu Gly Ala Ser Glu Val Pro His Ser Arg Gln Ala Ala
                 530                 535                 540

 Phe Ser Ser Pro Ile Glu Thr Asp Val Val Pro Asp Thr Arg Leu
                 545                 550                 555

 Leu Asp Lys Phe Ser Gln Ile Thr Pro Arg Leu Phe Met Pro Leu
                 560                 565                 570

 Asp Glu Thr Ile Gln Asn Pro Pro Met Glu Thr Leu Tyr Ile Ile
                 575                 580                 585

 Asp Phe Phe Ile Ala Leu Ala Ile Cys Asn Thr Val Val Val Ser
                 590                 595                 600

 Ala Pro Asn Gln Pro Arg Gln Lys Ile Arg His Pro Ser Leu Gly
                 605                 610                 615

 Gly Leu Pro Ile Lys Ser Leu Glu Glu Ile Lys Ser Leu Phe Gln
                 620                 625                 630

 Arg Trp Ser Val Arg Arg Ser Ser Ser Pro Ser Leu Asn Ser Gly
                 635                 640                 645

 Lys Glu Pro Ser Ser Gly Val Pro Asn Ala Phe Val Ser Arg Leu
                 650                 655                 660

 Pro Leu Phe Ser Arg Met Lys Pro Ala Ser Pro Val Glu Glu Glu
                 665                 670                 675

 Val Ser Gln Val Cys Glu Ser Pro Gln Cys Ser Ser Ser Ser Ala
                 680                 685                 690

 Cys Cys Thr Glu Thr Glu Lys Gln His Gly Asp Ala Gly Leu Leu
                 695                 700                 705

 Asn Gly Lys Ala Glu Ser Leu Pro Gly Gln Pro Leu Ala Cys Asn
                 710                 715                 720

 Leu Cys Tyr Glu Ala Glu Ser Pro Asp Glu Ala Ala Leu Val Tyr
                 725                 730                 735

 Ala Ala Arg Ala Tyr Gln Cys Thr Leu Arg Ser Arg Thr Pro Glu
                 740                 745                 750

 Gln Val Met Val Asp Phe Ala Ala Leu Gly Pro Leu Thr Phe Gln
                 755                 760                 765

 Leu Leu His Ile Leu Pro Phe Asp Ser Val Arg Lys Arg Met Ser
                 770                 775                 780

 Val Val Val Arg His Pro Leu Ser Asn Gln Val Val Val Tyr Thr
                 785                 790                 795

 Lys Gly Ala Asp Ser Val Ile Met Glu Leu Leu Ser Val Ala Ser
                 800                 805                 810

 Pro Asp Gly Ala Ser Leu Glu Lys Gln Gln Met Ile Val Arg Glu
                 815                 820                 825

 Lys Thr Gln Lys His Leu Asp Asp Tyr Ala Lys Gln Gly Leu Arg
                 830                 835                 840

 Thr Leu Cys Ile Ala Lys Lys Val Met Ser Asp Thr Glu Tyr Ala
                 845                 850                 855

 Glu Trp Leu Arg Asn His Phe Leu Ala Glu Thr Ser Ile Asp Asn
                 860                 865                 870

 Arg Glu Glu Leu Leu Leu Glu Ser Ala Met Arg Leu Glu Asn Lys
                 875                 880                 885

 Leu Thr Leu Leu Gly Ala Thr Gly Ile Glu Asp Arg Leu Gln Glu
                 890                 895                 900

 Gly Val Pro Glu Ser Ile Glu Ala Leu His Lys Ala Gly Ile Lys
                 905                 910                 915

 Ile Trp Met Leu Thr Gly Asp Lys Gln Glu Thr Ala Val Asn Ile
                 920                 925                 930

 Ala Tyr Ala Cys Lys Leu Leu Glu Pro Asp Asp Lys Leu Phe Ile
                 935                 940                 945

 Leu Asn Thr Gln Ser Lys Asp Ala Cys Gly Met Leu Met Ser Thr
                 950                 955                 960

 Ile Leu Lys Glu Leu Gln Lys Lys Thr Gln Ala Leu Pro Glu Gln
                 965                 970                 975

 Val Ser Leu Ser Glu Asp Leu Leu Gln Pro Pro Val Pro Arg Asp
                 980                 985                 990

 Ser Gly Leu Arg Ala Gly Leu Ile Ile Thr Gly Arg Thr Leu Glu
                 995                1000                1005

 Phe Ala Leu Gln Glu Ser Leu Gln Lys Gln Phe Leu Glu Leu Thr
                1010                1015                1020

 Ser Trp Cys Gln Ala Val Val Cys Cys Arg Ala Thr Pro Leu Gln
                1025                1030                1035

 Lys Ser Glu Val Val Lys Leu Val Arg Ser His Leu Gln Val Met
                1040                1045                1050

 Thr Leu Ala Ile Gly Asp Gly Ala Asn Asp Val Ser Met Ile Gln
                1055                1060                1065

 Val Ala Asp Ile Gly Ile Gly Val Ser Gly Gln Glu Gly Met Gln
                1070                1075                1080

 Ala Val Met Ala Ser Asp Phe Ala Val Tyr Gln Phe Lys His Leu
                1085                1090                1095

 Ser Lys Leu Leu Leu Val His Gly His Trp Cys Tyr Thr Arg Leu
                1100                1105                1110

 Ser Asn Met Ile Leu Tyr Phe Phe Tyr Lys Asn Val Ala Tyr Val
                1115                1120                1125

 Asn Leu Leu Phe Trp Tyr Gln Phe Phe Cys Gly Phe Ser Gly Thr
                1130                1135                1140

 Ser Met Thr Asp Tyr Trp Val Leu Ile Phe Phe Asn Leu Leu Phe
                1145                1150                1155

 Thr Ser Ala Pro Pro Val Ile Tyr Gly Val Leu Glu Lys Asp Val
                1160                1165                1170

 Ser Ala Glu Thr Leu Met Gln Leu Pro Glu Leu Tyr Arg Ser Gly
                1175                1180                1185

 Gln Lys Ser Glu Ala Tyr Leu Pro His Thr Phe Trp Ile Thr Leu
                1190                1195                1200

 Leu Asp Ala Phe Tyr Gln Ser Leu Val Cys Phe Phe Val Pro Tyr
                1205                1210                1215

 Phe Thr Tyr Gln Gly Ser Asp Thr Asp Ile Phe Ala Phe Gly Asn
                1220                1225                1230

 Pro Leu Asn Thr Ala Ala Leu Phe Ile Val Leu Leu His Leu Val
                1235                1240                1245

 Ile Glu Ser Lys Ser Leu Thr Trp Ile His Leu Leu Val Ile Ile
                1250                1255                1260

 Gly Ser Ile Leu Ser Tyr Phe Leu Phe Ala Ile Val Phe Gly Ala
                1265                1270                1275

 Met Cys Val Thr Cys Asn Pro Pro Ser Asn Pro Tyr Trp Ile Met
                1280                1285                1290

 Gln Glu His Met Leu Asp Pro Val Phe Tyr Leu Val Cys Ile Leu
                1295                1300                1305

 Thr Thr Ser Ile Ala Leu Leu Pro Arg Phe Val Tyr Arg Val Leu
                1310                1315                1320

 Gln Gly Ser Leu Phe Pro Ser Pro Ile Leu Arg Ala Lys His Phe
                1325                1330                1335

 Asp Arg Leu Thr Pro Glu Glu Arg Thr Lys Ala Leu Lys Lys Trp
                1340                1345                1350

 Arg Gly Ala Gly Lys Met Asn Gln Val Thr Ser Lys Tyr Ala Asn
                1355                1360                1365

 Gln Ser Ala Gly Lys Ser Gly Arg Arg Pro Met Pro Gly Pro Ser
                1370                1375                1380

 Ala Val Phe Ala Met Lys Ser Ala Ser Ser Cys Ala Ile Glu Gln
                1385                1390                1395

 Gly Asn Leu Ser Leu Cys Glu Thr Ala Leu Asp Gln Gly Tyr Ser
                1400                1405                1410

 Glu Thr Lys Ala Phe Glu Met Ala Gly Pro Ser Lys Gly Lys Glu
                1415                1420                1425

 Ser


<210> 2758
<211> 6827
<212> DNA
<213> Homo sapien

<400> 2758
 ctccagaagg tttttgttgc atttagagaa tttaatctgt ctgaaagcaa 50

 agtttgtgaa ctgcagttgc cggatatcaa tctcgtgaat gaccagaaga 100

 aattagtatc ttcagatctt tggagaattg tcttgaacag cagtcaaaat 150

 ggagctgatg accaaagctc tgcaagtgag tctggttctc aaagcacttg 200

 tgatccactt gtgactccaa cagccctggc tgcctgtacc agagttgact 250

 cctgctttac cccatggttt gtcccatccc tttgcgtttc tttccagttt 300

 gctcacctgg aattccatct ttgtcatcac cttgaccaac taggcacagc 350

 tgcaccacag tacctacagc catttgtttc cgacagaaat atgccatctg 400

 aactagaata catgattgtt tccttcagag aaccacacat gtatcttcga 450

 cagtggaata atggttctgt ctgtcaggag atccagttct tagctcaagc 500

 agactgtaaa cttctagagt gcagaaatgt cactatgcaa agtgtggtga 550

 aacccttcag catcttcggg cagatggcag tttccagcga tgtagtggaa 600

 aagctgcttg actgcaccgt gatagttgat tctgtatttg taaaccttgg 650

 acagcatgta gtccattcac taaacactgc aatacaagct tggcaacaga 700

 acaaatgccc tgaggtagag gagttggtct tcagccattt tgtgatctgt 750

 aatgacacac aggagacact gcggtttggc caggtggata ctgatgaaaa 800

 tattctgctg gcgagtctcc acagtcacca gtacagctgg cgctctcaca 850

 aatccccaca gctgttacac atctgtattg aaggttgggg caactggcgt 900

 tggtcagagc ctttcagtgt ggaccatgcc gggactttta ttagaacaat 950

 tcagtacagg ggtcgaactg cttctctcat catcaaggtt cagcaactca 1000

 atggagtaca aaaacagatt atcatctgtg gaagacagat catctgtagt 1050

 tacttgtctc aaagcataga actaaaagtc gttcagcatt acattggtca 1100

 agatggacaa gctgtagttc gggaacattt tgactgcctc acagccaaac 1150

 agaaattgcc ttcgtacata ctagaaaaca atgaactgac ggagctgtgt 1200

 gtgaaggcca aaggagatga agactggtca agagatgtgt gcctggaatc 1250

 caaagcccct gagtacagca ttgtcattca ggtgccatct tcaaacagtt 1300

 ccattattta tgtctggtgc acagttttga ctttagaacc caactctcaa 1350

 gtgcaacaac gaatgattgt gttcagccct ctttttatca tgaggagtca 1400

 tcttccagac cccattatca tacatttgga gaaaaggagt ctgggattga 1450

 gtgaaacaca aattattcca ggaaaagggc aggaaaaacc actgcaaaac 1500

 atagaacctg accttgtaca tcacctgaca ttccaagcaa gagaagaata 1550

 tgatccttca gattgtgcag ttcccatctc aacatccctc attaagcaaa 1600

 tagccactaa ggtacaccct ggaggcacag ttaatcagat ccttgacgaa 1650

 ttctatgggc cagaaaagtc gcttcaaccc atatggccct ataataagaa 1700

 ggattctgac aggaatgaac agctaagtca gtgggatagc ccaatgcgag 1750

 tgaagctgtc aatctggaag ccatatgtta gaactttgtt gatagaactt 1800

 ctgccctggg ccctgcttat caatgaatcc aaatgggacc tctggctatt 1850

 tgaaggagag aaaattgttc tacaggttcc tgctggcaaa attattattc 1900

 ctcctaattt tcaggaagct tttcaaattg gaatatactg ggcaaataca 1950

 aacactgtgc acaagtcagt agcaattaaa ctggtccata acctgacatc 2000

 tccaaagtgg aaagatggag gtaatggtga agttgtgaca ctggatgaag 2050

 aagcgtttgt tgatactgaa ataagacttg gtgcttttcc aggacatcag 2100

 aagttatgtc agttctgcat ttcctccatg gtacagcaag gtatacaaat 2150

 tattcagatt gaagacaaga ctacaataat caataataca ccatatcaaa 2200

 tattttataa accacagcta tctgtctgca atccccattc tggaaaggag 2250

 tattttcgtg ttccagacag tgctactttt agcatttgcc caggtggaga 2300

 gcagcctgct atgaaatcca gctcccttcc ttgctgggac ttgatgcctg 2350

 acatcagtca gtcagtactg gatgcatccc tgcttcagaa acagatcatg 2400

 ctgggctttt ctcctgcccc aggtgctgac agctcacagt gctggagcct 2450

 gccagctata gttagaccag agtttcccag acagagtgtg gcagtacccc 2500

 tcgggaattt ccgggaaaat ggattctgta ccagggctat agtgctgaca 2550

 tatcaagaac acctcggagt gacttattta accctctcag aagaccctag 2600

 tcctcgagta attatccaca atagatgtcc agtaaaaatg cttataaagg 2650

 aaaacattaa agatattcca aagtttgagg tttattgcaa aaaaattccc 2700

 tccgagtgct caattcatca tgagctgtat catcagattt ccagttatcc 2750

 ggactgcaag accaaagact tacttccaag cctacttttg agagttgaac 2800

 ctctagatga agtaacaact gagtggagtg atgccattga catcaacagt 2850

 cagggaacac aggttgtgtt cctgactggc tttggctatg tgtatgtgga 2900

 tgttgtacat cagtgtggca cagtcttcat cactgtggcc ccagaaggaa 2950

 aagcaggacc tattttaacc aataccaaca gagcgccaga gaagattgtt 3000

 acatttaaaa tgttcatcac tcagttaagc ctggcagtgt ttgatgacct 3050

 cacccaccac aaagcatcag ctgagcttct gagactcaca ctggacaaca 3100

 tttttctctg tgtggccccg ggagctggtc ccctccctgg ggaagagcct 3150

 gtggctgcgt tgtttgaact ttactgtgtg gagatctgct gtggggacct 3200

 gcagctagac aaccagcttt ataacaagtc caatttccac tttgctgtct 3250

 tagtctgcca gggagaaaaa gcagaaccca ttcagtgttc caaaatgcag 3300

 agtctcctca tatccaacaa agagttggaa gaatacaagg aaaaatgttt 3350

 tatcaaactt tgcatcacct taaatgaagg caagagcatc ctctgtgata 3400

 ttaatgagtt cagctttgaa ttaaaacctg ctcggttata cgtggaagac 3450

 acatttgtat actacatcaa gactttgttt gacacctacc ttcctaacag 3500

 caggttggct ggtcactcca cacacctctc cgggggtaaa caggtgttgc 3550

 ccatgcaggt cacacagcac gccagggcct tggtgaatcc tgtgaagtta 3600

 cggaaactgg tgatccagcc agtaaatttg ctcgtcagca tccacgcttc 3650

 cctcaagctg tacatagcct cagaccacac tcctctctcc ttctcggtgt 3700

 ttgaaagagg acccatcttc accactgcga ggcagcttgt gcacgccctg 3750

 gcaatgcact atgccgctgg ggcccttttt agagcaggct gggtagttgg 3800

 gtctctggat attcttggca gccctgcaag cctggtgaga agcatcggga 3850

 acggggtcgc cgacttcttc aggcttccgt atgaggggct gacccggggc 3900

 cctggagcct tcgtgagtgg cgtctccaga gggaccacat cgtttgtaaa 3950

 gcacatctcc aaaggtaccc tcacatccat caccaacctc gccacaagcc 4000

 tggcccggaa catggaccgg ctctcactgg atgaggagca ctacaaccgg 4050

 caggaggagt ggcggcggca gctccccgag agcctgggcg aggggcttcg 4100

 acagggcctg tcccggctgg gcatcagcct gcttggtgca attgctggta 4150

 tagttgatca gccgatgcag aacttccaga aaacatctga ggcacaggct 4200

 tcagcaggac acaaggccaa gggtgtcatc tcgggtgtgg ggaaaggaat 4250

 catgggggtg ttcacaaagc ccatcggagg agctgctgag ctggtgtcac 4300

 agactggcta tggtatttta catggagctg gactttctca gcttcccaaa 4350

 cagcgccatc agccaagtga tctacatgct gaccaggctc caaacagcca 4400

 tgtcaaatat gtctggaaaa tgcttcagtc tctgggcaga ccagaagtcc 4450

 acatggccct ggacgtggtt ctggtgaggg gctcaggcca ggagcatgaa 4500

 gggtgcttgc tgctgacatc agaagtgctc ttcgtggtga gtgtcagtga 4550

 ggacacacag cagcaggcct tccccgtcac agaaatcgac tgtgcacagg 4600

 acagcaagca gaacaactta ctcacagtgc agctcaagca gccaagagtg 4650

 gcctgtgatg tggaggtaga tggagtccga gagagactgt cagagcaaca 4700

 gtacaacaga ctggtggact acatcacaaa gacatcttgt cacctggccc 4750

 ccagctgttc ttccatgcaa ataccatgcc ctgtggtggc tgcagaacct 4800

 cccccctcca ctgttaaaac ataccattac ctggttgatc cacattttgc 4850

 tcaggtcttc cttagtaaat ttaccatggt gaaaaataaa gccctgagga 4900

 aagggtttcc ttgagtcccc tctgaggtgt ttattcctgc ttgtgtgatt 4950

 tagtttttgg gtttctttga gacagggtct cactgcattg cccttgctga 5000

 cctcaaattc tggggttcaa gcaatcctcc cacctcaacc cacaagtagc 5050

 tacgactgca agcacctgcc accataaagg gctgcatttt gccaccataa 5100

 agggctgcat ttttttaaaa agcctaggca gctctaacat catctgatat 5150

 ggacacaagg ccaacagttt ccttatttac atccttacct ctaaaagata 5200

 cttcaaagtg acaaaaacgt gttccttccc cacttagaga caatgattaa 5250

 cagggcccta tatgttctta ccacatacag aggatgcatt tatttttgct 5300

 ctatgacact tgcaaaaatc tctactgtaa ttaatttggg tctattatta 5350

 actctctgtt ccatcataga atgtggccag gccttacaat ggagagccag 5400

 agttaaaact tcaagttgca tctgtttttg ggctgagtca ccacctttgc 5450

 ctcatgctcc tttgtctgca aaggcctagg attctttctt taaatgaaat 5500

 gcttaggact ttgtggcttg ttacatttgt catttaactg cagtgctatt 5550

 ctttgaaagc tgctatgtgt attttctctg aagtctgcat tttactaaaa 5600

 tttacaacag tctgatgatt gattgattac tgtccaggta cattttagaa 5650

 aaagtgttct tcttccagtt tgttttacta agcaaacttt gagtaaatcc 5700

 tttgtcctat attgaatcca gtcccaaagt gttcaggtga gtttctctag 5750

 ttccataaac aaaacataca tagtgggaac tccctggtat gccatagagc 5800

 acacaagaac cccaatatta atgctaacaa ttataccagt ccattttgtt 5850

 tattctgtgg aattgacttg acaaagcatg aagatattcc cagtgtctgt 5900

 ctgataatat tttgcatcta agaatgggtt tgactcaaga tcttgggtta 5950

 ccaagatgtc ttaaatgttc agtaaatatc tttcttacag tccagtagct 6000

 tagagcatgt ttgctgattg atattacatt taaacttggg gctacagctt 6050

 gttacctaga attttgagat actaagagaa tgcaatttta aatgcccact 6100

 ggttttattt gttttggaga gagggtctca ttctgtcacc caggctagag 6150

 tacagtggga acagtcatgg ctcactgcag cttaagctca ctgcctgggc 6200

 tcaagtgatc ttactccagc ctcccaagca gctgggacta caccaccaca 6250

 ggtatgcacc accatacctg gctgattttt aaaatttttt ctagagatga 6300

 ggtctcacta tgttgcccag ctggtctcat actcctcagt tcacgcattc 6350

 ctcccacctc cacctcccaa actgctggga ttacaggtgt gagccaccat 6400

 gcccaacacc cactgatctt taactctcac atgttgggca taagaagtca 6450

 ctatataatt gttactggaa agcaagactt aacgaacaat tctgactatg 6500

 aaaaatgtct ctttcagttt gttctgtaaa tatttagaaa agtgacagct 6550

 gtcaacctca gagtaactat ttctaaaaat gtaaatatgt attaatcctt 6600

 gtatctttta tggtaatttt gcatattgat atgaattata taaaattgtt 6650

 taaaataaaa ggtgtccttg aattactgac cacccataga tgtctactgt 6700

 taccaggttt tacaatgcaa attttcacta atacctgggt ttaatacagc 6750

 tcacatcact gaatgttaca catgagttta aatgggtaat atacaggttt 6800

 tgttataata aagttactga ttaaatt 6827

<210> 2759
<211> 1637
<212> PRT
<213> Homo sapien

<400> 2759
 Leu Gln Lys Val Phe Val Ala Phe Arg Glu Phe Asn Leu Ser Glu
   1               5                  10                  15

 Ser Lys Val Cys Glu Leu Gln Leu Pro Asp Ile Asn Leu Val Asn
                  20                  25                  30

 Asp Gln Lys Lys Leu Val Ser Ser Asp Leu Trp Arg Ile Val Leu
                  35                  40                  45

 Asn Ser Ser Gln Asn Gly Ala Asp Asp Gln Ser Ser Ala Ser Glu
                  50                  55                  60

 Ser Gly Ser Gln Ser Thr Cys Asp Pro Leu Val Thr Pro Thr Ala
                  65                  70                  75

 Leu Ala Ala Cys Thr Arg Val Asp Ser Cys Phe Thr Pro Trp Phe
                  80                  85                  90

 Val Pro Ser Leu Cys Val Ser Phe Gln Phe Ala His Leu Glu Phe
                  95                 100                 105

 His Leu Cys His His Leu Asp Gln Leu Gly Thr Ala Ala Pro Gln
                 110                 115                 120

 Tyr Leu Gln Pro Phe Val Ser Asp Arg Asn Met Pro Ser Glu Leu
                 125                 130                 135

 Glu Tyr Met Ile Val Ser Phe Arg Glu Pro His Met Tyr Leu Arg
                 140                 145                 150

 Gln Trp Asn Asn Gly Ser Val Cys Gln Glu Ile Gln Phe Leu Ala
                 155                 160                 165

 Gln Ala Asp Cys Lys Leu Leu Glu Cys Arg Asn Val Thr Met Gln
                 170                 175                 180

 Ser Val Val Lys Pro Phe Ser Ile Phe Gly Gln Met Ala Val Ser
                 185                 190                 195

 Ser Asp Val Val Glu Lys Leu Leu Asp Cys Thr Val Ile Val Asp
                 200                 205                 210

 Ser Val Phe Val Asn Leu Gly Gln His Val Val His Ser Leu Asn
                 215                 220                 225

 Thr Ala Ile Gln Ala Trp Gln Gln Asn Lys Cys Pro Glu Val Glu
                 230                 235                 240

 Glu Leu Val Phe Ser His Phe Val Ile Cys Asn Asp Thr Gln Glu
                 245                 250                 255

 Thr Leu Arg Phe Gly Gln Val Asp Thr Asp Glu Asn Ile Leu Leu
                 260                 265                 270

 Ala Ser Leu His Ser His Gln Tyr Ser Trp Arg Ser His Lys Ser
                 275                 280                 285

 Pro Gln Leu Leu His Ile Cys Ile Glu Gly Trp Gly Asn Trp Arg
                 290                 295                 300

 Trp Ser Glu Pro Phe Ser Val Asp His Ala Gly Thr Phe Ile Arg
                 305                 310                 315

 Thr Ile Gln Tyr Arg Gly Arg Thr Ala Ser Leu Ile Ile Lys Val
                 320                 325                 330

 Gln Gln Leu Asn Gly Val Gln Lys Gln Ile Ile Ile Cys Gly Arg
                 335                 340                 345

 Gln Ile Ile Cys Ser Tyr Leu Ser Gln Ser Ile Glu Leu Lys Val
                 350                 355                 360

 Val Gln His Tyr Ile Gly Gln Asp Gly Gln Ala Val Val Arg Glu
                 365                 370                 375

 His Phe Asp Cys Leu Thr Ala Lys Gln Lys Leu Pro Ser Tyr Ile
                 380                 385                 390

 Leu Glu Asn Asn Glu Leu Thr Glu Leu Cys Val Lys Ala Lys Gly
                 395                 400                 405

 Asp Glu Asp Trp Ser Arg Asp Val Cys Leu Glu Ser Lys Ala Pro
                 410                 415                 420

 Glu Tyr Ser Ile Val Ile Gln Val Pro Ser Ser Asn Ser Ser Ile
                 425                 430                 435

 Ile Tyr Val Trp Cys Thr Val Leu Thr Leu Glu Pro Asn Ser Gln
                 440                 445                 450

 Val Gln Gln Arg Met Ile Val Phe Ser Pro Leu Phe Ile Met Arg
                 455                 460                 465

 Ser His Leu Pro Asp Pro Ile Ile Ile His Leu Glu Lys Arg Ser
                 470                 475                 480

 Leu Gly Leu Ser Glu Thr Gln Ile Ile Pro Gly Lys Gly Gln Glu
                 485                 490                 495

 Lys Pro Leu Gln Asn Ile Glu Pro Asp Leu Val His His Leu Thr
                 500                 505                 510

 Phe Gln Ala Arg Glu Glu Tyr Asp Pro Ser Asp Cys Ala Val Pro
                 515                 520                 525

 Ile Ser Thr Ser Leu Ile Lys Gln Ile Ala Thr Lys Val His Pro
                 530                 535                 540

 Gly Gly Thr Val Asn Gln Ile Leu Asp Glu Phe Tyr Gly Pro Glu
                 545                 550                 555

 Lys Ser Leu Gln Pro Ile Trp Pro Tyr Asn Lys Lys Asp Ser Asp
                 560                 565                 570

 Arg Asn Glu Gln Leu Ser Gln Trp Asp Ser Pro Met Arg Val Lys
                 575                 580                 585

 Leu Ser Ile Trp Lys Pro Tyr Val Arg Thr Leu Leu Ile Glu Leu
                 590                 595                 600

 Leu Pro Trp Ala Leu Leu Ile Asn Glu Ser Lys Trp Asp Leu Trp
                 605                 610                 615

 Leu Phe Glu Gly Glu Lys Ile Val Leu Gln Val Pro Ala Gly Lys
                 620                 625                 630

 Ile Ile Ile Pro Pro Asn Phe Gln Glu Ala Phe Gln Ile Gly Ile
                 635                 640                 645

 Tyr Trp Ala Asn Thr Asn Thr Val His Lys Ser Val Ala Ile Lys
                 650                 655                 660

 Leu Val His Asn Leu Thr Ser Pro Lys Trp Lys Asp Gly Gly Asn
                 665                 670                 675

 Gly Glu Val Val Thr Leu Asp Glu Glu Ala Phe Val Asp Thr Glu
                 680                 685                 690

 Ile Arg Leu Gly Ala Phe Pro Gly His Gln Lys Leu Cys Gln Phe
                 695                 700                 705

 Cys Ile Ser Ser Met Val Gln Gln Gly Ile Gln Ile Ile Gln Ile
                 710                 715                 720

 Glu Asp Lys Thr Thr Ile Ile Asn Asn Thr Pro Tyr Gln Ile Phe
                 725                 730                 735

 Tyr Lys Pro Gln Leu Ser Val Cys Asn Pro His Ser Gly Lys Glu
                 740                 745                 750

 Tyr Phe Arg Val Pro Asp Ser Ala Thr Phe Ser Ile Cys Pro Gly
                 755                 760                 765

 Gly Glu Gln Pro Ala Met Lys Ser Ser Ser Leu Pro Cys Trp Asp
                 770                 775                 780

 Leu Met Pro Asp Ile Ser Gln Ser Val Leu Asp Ala Ser Leu Leu
                 785                 790                 795

 Gln Lys Gln Ile Met Leu Gly Phe Ser Pro Ala Pro Gly Ala Asp
                 800                 805                 810

 Ser Ser Gln Cys Trp Ser Leu Pro Ala Ile Val Arg Pro Glu Phe
                 815                 820                 825

 Pro Arg Gln Ser Val Ala Val Pro Leu Gly Asn Phe Arg Glu Asn
                 830                 835                 840

 Gly Phe Cys Thr Arg Ala Ile Val Leu Thr Tyr Gln Glu His Leu
                 845                 850                 855

 Gly Val Thr Tyr Leu Thr Leu Ser Glu Asp Pro Ser Pro Arg Val
                 860                 865                 870

 Ile Ile His Asn Arg Cys Pro Val Lys Met Leu Ile Lys Glu Asn
                 875                 880                 885

 Ile Lys Asp Ile Pro Lys Phe Glu Val Tyr Cys Lys Lys Ile Pro
                 890                 895                 900

 Ser Glu Cys Ser Ile His His Glu Leu Tyr His Gln Ile Ser Ser
                 905                 910                 915

 Tyr Pro Asp Cys Lys Thr Lys Asp Leu Leu Pro Ser Leu Leu Leu
                 920                 925                 930

 Arg Val Glu Pro Leu Asp Glu Val Thr Thr Glu Trp Ser Asp Ala
                 935                 940                 945

 Ile Asp Ile Asn Ser Gln Gly Thr Gln Val Val Phe Leu Thr Gly
                 950                 955                 960

 Phe Gly Tyr Val Tyr Val Asp Val Val His Gln Cys Gly Thr Val
                 965                 970                 975

 Phe Ile Thr Val Ala Pro Glu Gly Lys Ala Gly Pro Ile Leu Thr
                 980                 985                 990

 Asn Thr Asn Arg Ala Pro Glu Lys Ile Val Thr Phe Lys Met Phe
                 995                1000                1005

 Ile Thr Gln Leu Ser Leu Ala Val Phe Asp Asp Leu Thr His His
                1010                1015                1020

 Lys Ala Ser Ala Glu Leu Leu Arg Leu Thr Leu Asp Asn Ile Phe
                1025                1030                1035

 Leu Cys Val Ala Pro Gly Ala Gly Pro Leu Pro Gly Glu Glu Pro
                1040                1045                1050

 Val Ala Ala Leu Phe Glu Leu Tyr Cys Val Glu Ile Cys Cys Gly
                1055                1060                1065

 Asp Leu Gln Leu Asp Asn Gln Leu Tyr Asn Lys Ser Asn Phe His
                1070                1075                1080

 Phe Ala Val Leu Val Cys Gln Gly Glu Lys Ala Glu Pro Ile Gln
                1085                1090                1095

 Cys Ser Lys Met Gln Ser Leu Leu Ile Ser Asn Lys Glu Leu Glu
                1100                1105                1110

 Glu Tyr Lys Glu Lys Cys Phe Ile Lys Leu Cys Ile Thr Leu Asn
                1115                1120                1125

 Glu Gly Lys Ser Ile Leu Cys Asp Ile Asn Glu Phe Ser Phe Glu
                1130                1135                1140

 Leu Lys Pro Ala Arg Leu Tyr Val Glu Asp Thr Phe Val Tyr Tyr
                1145                1150                1155

 Ile Lys Thr Leu Phe Asp Thr Tyr Leu Pro Asn Ser Arg Leu Ala
                1160                1165                1170

 Gly His Ser Thr His Leu Ser Gly Gly Lys Gln Val Leu Pro Met
                1175                1180                1185

 Gln Val Thr Gln His Ala Arg Ala Leu Val Asn Pro Val Lys Leu
                1190                1195                1200

 Arg Lys Leu Val Ile Gln Pro Val Asn Leu Leu Val Ser Ile His
                1205                1210                1215

 Ala Ser Leu Lys Leu Tyr Ile Ala Ser Asp His Thr Pro Leu Ser
                1220                1225                1230

 Phe Ser Val Phe Glu Arg Gly Pro Ile Phe Thr Thr Ala Arg Gln
                1235                1240                1245

 Leu Val His Ala Leu Ala Met His Tyr Ala Ala Gly Ala Leu Phe
                1250                1255                1260

 Arg Ala Gly Trp Val Val Gly Ser Leu Asp Ile Leu Gly Ser Pro
                1265                1270                1275

 Ala Ser Leu Val Arg Ser Ile Gly Asn Gly Val Ala Asp Phe Phe
                1280                1285                1290

 Arg Leu Pro Tyr Glu Gly Leu Thr Arg Gly Pro Gly Ala Phe Val
                1295                1300                1305

 Ser Gly Val Ser Arg Gly Thr Thr Ser Phe Val Lys His Ile Ser
                1310                1315                1320

 Lys Gly Thr Leu Thr Ser Ile Thr Asn Leu Ala Thr Ser Leu Ala
                1325                1330                1335

 Arg Asn Met Asp Arg Leu Ser Leu Asp Glu Glu His Tyr Asn Arg
                1340                1345                1350

 Gln Glu Glu Trp Arg Arg Gln Leu Pro Glu Ser Leu Gly Glu Gly
                1355                1360                1365

 Leu Arg Gln Gly Leu Ser Arg Leu Gly Ile Ser Leu Leu Gly Ala
                1370                1375                1380

 Ile Ala Gly Ile Val Asp Gln Pro Met Gln Asn Phe Gln Lys Thr
                1385                1390                1395

 Ser Glu Ala Gln Ala Ser Ala Gly His Lys Ala Lys Gly Val Ile
                1400                1405                1410

 Ser Gly Val Gly Lys Gly Ile Met Gly Val Phe Thr Lys Pro Ile
                1415                1420                1425

 Gly Gly Ala Ala Glu Leu Val Ser Gln Thr Gly Tyr Gly Ile Leu
                1430                1435                1440

 His Gly Ala Gly Leu Ser Gln Leu Pro Lys Gln Arg His Gln Pro
                1445                1450                1455

 Ser Asp Leu His Ala Asp Gln Ala Pro Asn Ser His Val Lys Tyr
                1460                1465                1470

 Val Trp Lys Met Leu Gln Ser Leu Gly Arg Pro Glu Val His Met
                1475                1480                1485

 Ala Leu Asp Val Val Leu Val Arg Gly Ser Gly Gln Glu His Glu
                1490                1495                1500

 Gly Cys Leu Leu Leu Thr Ser Glu Val Leu Phe Val Val Ser Val
                1505                1510                1515

 Ser Glu Asp Thr Gln Gln Gln Ala Phe Pro Val Thr Glu Ile Asp
                1520                1525                1530

 Cys Ala Gln Asp Ser Lys Gln Asn Asn Leu Leu Thr Val Gln Leu
                1535                1540                1545

 Lys Gln Pro Arg Val Ala Cys Asp Val Glu Val Asp Gly Val Arg
                1550                1555                1560

 Glu Arg Leu Ser Glu Gln Gln Tyr Asn Arg Leu Val Asp Tyr Ile
                1565                1570                1575

 Thr Lys Thr Ser Cys His Leu Ala Pro Ser Cys Ser Ser Met Gln
                1580                1585                1590

 Ile Pro Cys Pro Val Val Ala Ala Glu Pro Pro Pro Ser Thr Val
                1595                1600                1605

 Lys Thr Tyr His Tyr Leu Val Asp Pro His Phe Ala Gln Val Phe
                1610                1615                1620

 Leu Ser Lys Phe Thr Met Val Lys Asn Lys Ala Leu Arg Lys Gly
                1625                1630                1635

 Phe Pro


<210> 2760
<211> 8859
<212> DNA
<213> Homo sapien

<400> 2760
 ggtcttcagg agagccagga gaggccagtt gtcacgtgcc tgaaacatga 50

 ggacttcgag ttggctttcc ttctcttgac caagggcgca gacccccgtg 100

 ctatttctct cacggaaggt gatactcctt tgcatgcagc actccacatc 150

 tttctagaga ttaaagctga cattggtttt agcttcctca gccatctgtt 200

 ggatctgttt tggtccaacc ccactgaatt cgactacctc aaccccaatg 250

 tccaggacag caatgggaac acgctgatgc acatcctctt ccagaagggc 300

 atgctaaagc gcgtgaagaa gctgttagac ctgctggtga agtttgacat 350

 caacttcaat ctgaagaaca aagagggcaa agatgcacgg caccggatta 400

 agaagaacga ctctctgctc ttggcctgga acaaagctct gatggagaac 450

 aggaggagga gccggcagga ctctgctgcc cacctgggga agctctcaaa 500

 gtccactgcc cctggtcaca catctcagct caagtcccag ggttcattca 550

 agtcagtgcc atgtggtgcc actgccagaa cactgcctga aggaagtgca 600

 gtccctgaca gctgggagac tctcccaggt acccaggtga ccaggaagga 650

 gcctggagct ctcaggccct gctcgctgag agactgcctt atgcaggaca 700

 tcacagtttt gattcagcag gttgaagtgg atccgtcttt cccagaggac 750

 tgtcttcaga gctctgagcc tctggaggca ggagctggca aagaaggaaa 800

 gaaagatgac aagccgactc tgggtgcagg ggcccctgac tgtagtgagg 850

 tgggggaagg acatgctcag gtgggtcttg gggccttgca gcttgtgcct 900

 gatgataaca gggggaagga gggcaatgat gatcaggatg actggagcac 950

 gcaggagatt gaggcctgcc tccaggactt cgataacatg acctgggaga 1000

 tcgagtgcac ttcagaaatg ctgaagaagc tgtctagtaa ggtaatgacc 1050

 aaggtcatca agaagaaaat catccttgcc attcagcagc tgggaaatgg 1100

 cgagtggacc cagggcctgc agaagcgact gaagcacctg aaaggaagca 1150

 tccagctctt cgaagctaag ctggacaaag gagcccggat gctctgggag 1200

 ctcgccattg acttctcccc tcgatgcagt gagaaccctg agaagatcat 1250

 tgccacggag cagaacacgt gtgcaatgga gaaatcaggg cggatctaca 1300

 cggaaatcat ccggatttgg gacatcgtct tagatcactg caaactggct 1350

 gattccatca aggccatctg caatgcctac aaccggggct tgtcctgtgt 1400

 cctgcggaag aagctgaaag gtatcaataa aggccaagtg tcagctaaca 1450

 tgaaaattca aaagcgtata cctcgctgct atgtggagga cacagaggcc 1500

 gagaagggca gggagcatgt caatcctgag tactttcccc cagccagtgc 1550

 agtggagaca gaatataaca tcatgaagtt ccacagcttc agcaccaaca 1600

 tggcctttaa catcctcaat gacacgacag ccacagtgga gtaccccttc 1650

 cgggtgggtg agcttgagta cgcggtgatc gacctcaatc ccaggccact 1700

 ggagcccatc atccttattg ggcgaagtgg cactgggaag acaacctgct 1750

 gcttgtacag attgtggaag aaattccacg tttactggga aaaagctgag 1800

 caggcaggaa gcccattgct ggccaaacag gtctggctga agagaaggtt 1850

 ggaagtggaa cccggaaaag agagtccagg tggggaggaa gagggggagg 1900

 aagaggacga ggaagaggaa gattctattg aagtggaaac agtagaaagc 1950

 atagatgagc aggagtatga agcctgcgca ggaggagccg gtgtggagcc 2000

 agcaggggac ggccaagctg cagaagtatg tgcaccagaa catccccacc 2050

 agctggagca tttacatcag atctttgtga ccaagaacca tgtgctgtgc 2100

 caggaggtac aaaggaattt cattgagctt tccaagtcca ccaaggccac 2150

 tagtcattac aaaccactgg accccaacat tcacaaactc caggacctga 2200

 gggacgagaa ctttcctctg tttgtcactt ccaagcagct gcttcttctg 2250

 cttgatgctt ctctgcccaa accatttttt ctgagaaacg aagatggaag 2300

 cttgaaaaga accatcatag gatggtctgc acaggaagag tcaaccattc 2350

 ctagttggca agaggatgaa gaggaggctg aggtggatgg ggactacagt 2400

 gaggaggata aagctgtaga aatgcgtacg ggtgacagtg acccccgggt 2450

 gtacgtgacg tttgaggtgt tcaaaaatga aatatggccc aaaatgacca 2500

 aagggaggac tgcctacaac cctgcactga tttggaaaga aataaaatct 2550

 tttctaaagg gttcttttga ggccctcagc tgtccccatg ggagactcac 2600

 tgaagaagta tataagaaat tagggaggaa acggtgcccc aatttcaagg 2650

 aagaccggag tgagatctac agcctcttca gtctgtatca gcaaatcagg 2700

 tcccagaaag gttattttga tgaagaggat gttctgtaca acatatcccg 2750

 gaggctgtcg aagctcaggg tgctcccatg gtccatccac gagctctatg 2800

 gtgatgagat tcaagacttt acccaggccg agctggcgct gctgatgaaa 2850

 tgcatcaatg accccaactc tatgttcctc acgggggaca cggcccagag 2900

 catcatgaag ggcgtggcct tccgcttcag cgatctgcgc tctctgttcc 2950

 attatgccag cagaaacacc atagacaagc agtgtgctgt ccggaagccc 3000

 aagaagatcc accagctgta ccagaattac aggtcccact caggaatcct 3050

 caatctggca tctggagtgg tggatttact tcagttctat ttcccagaat 3100

 cttttgatcg ccttccaagg gattctggcc tctttgatgg tcctaagcca 3150

 actgttctgg agtcttgtag tgtaagcgac ttggcaattt tgctacgagg 3200

 gaataaaagg aaaactcagc ccattgaatt tggagcccac caggtaatcc 3250

 ttgtggccaa tgaaacggca aaggagaaaa ttccagaaga gctggggtta 3300

 gcacttgtgc taacaattta tgaagcaaaa ggcttagaat ttgatgatgt 3350

 cctcctttac aactttttta ctgattctga ggcttataag gaatggaaga 3400

 tcatttcctc attcacacct acctcaactg actccagaga ggaaaaccgg 3450

 ccattggttg aagtacccct ggacaaacca ggctcttctc agggtcgatc 3500

 tctcatggtg aatccagaaa tgtacaagct cctcaacgga gagctgaagc 3550

 agctgtacac cgccatcaca cgggctcggg tcaacctctg gatctttgat 3600

 gaaaaccgag agaaacgggc tcccgcattc aaatatttca ttagaagaga 3650

 ttttgtccaa gttgtaaaga cagatgaaaa taaagacttt gatgatagca 3700

 tgttcgttaa gacctcaact cctgcggagt ggattgcaca gggagattac 3750

 tacgccaagc accagtgctg gaaggttgca gccaagtgtt accagaaagg 3800

 aggtgcattt gagaaggaga agttggccct ggcccatgac actgccctga 3850

 gcatgaaatc caagaaagtc agccccaagg aaaagcagtt ggaatatttg 3900

 gaattggcta agacctattt ggagtgcaaa gagccaacac tgtcccttaa 3950

 gtgtctgagc tatgccaagg agttccagct ctctgcccag ctgtgcgaga 4000

 ggctgggaaa gataagagat gctgcctatt tctataagcg aagccagtgc 4050

 tacaaagacg ctttcagatg ctttgagcag attcaggaat ttgatctagc 4100

 actcaaaatg tactgccaag aggagctttt tgaagaagct gctattgcag 4150

 tggaaaagta tgaagaaatg ctaaagacta agacccttcc catttccaag 4200

 ctctcctatt ctgccagtca gttttacttg gaagctgcag caaagtatct 4250

 gagtgcaaat aagatgaagg aaatgatggc tgtcctctca aagctagaca 4300

 tagaagacca gctggtgttc ttgaagtctc ggaaacgctt agcagaagct 4350

 gcagacctgc tgaacaggga aggtaggaga gaagaggctg ccctgctgat 4400

 gaagcaacat ggctgcctcc tggaggctgc caggctcact gccgacaagg 4450

 acttccaggc ctcatgtctg ctgggggccg cccgcctcaa tgtggccagg 4500

 gattccgaca tagaacacac caaggacatt ctgagagaag cacttgatat 4550

 ctgctatcaa actggccagt tgtctggcat tgcggaggcc cacttcctgc 4600

 aaggggtaat cctgagagac tttcagaagc tcagggatgc cttcttcaag 4650

 tttgacacgc tcaaccactc agctggagtg gtggaagcac tctacgaagc 4700

 agccagccag tgtgaggccg agcctgagaa gattctgggc ctggctccag 4750

 ggggcttgga aatcctcctc agtctggtca gggctctcaa aagagtgacc 4800

 aacaatgctg agaaggaaat ggtcaaatct tgctttgagt tttttgggat 4850

 ttcccaggtg gatgccaagt attgccagat agctcagaat gaccctgggc 4900

 ccatattaag aataattttt gacctggatt tgaacttgag agagaaaaaa 4950

 acaaaagatc attttttgat aatgactgac caagtgaaat tagccctaaa 5000

 caaacacctt ttgggcaggc tgtgtcagat cacacggagc ctgcttggga 5050

 agacctaccg aggagtctgc atgaggttta ttgtaggctt aaaatgtgag 5100

 gatgaaaact gtgaacattt tcacaggcct ctgcggcgtt gtgaagccaa 5150

 gtgtttagtt cagtcgaaaa tgaacttggt ggcaatcaac gggttgcttt 5200

 tggaagccaa aaaagtattc cctaaaatct tagcagaaga acttaaagaa 5250

 attgattata ttttgtctac agatatgtat ggcctttgca agtccattct 5300

 ggatgtcctt ttccctaagc atttccatca gagagtgttg tcagaaaacc 5350

 ccatggcatg caaagaaatc ctcaaaccaa attacaaatc cttccggttc 5400

 tacagatttg ctttgaagga gtacatccac tttctgtttg aaaatgaaag 5450

 cgcacgcaac cgccgggaat ccacagacct gtggctgagt gccatgcaag 5500

 ctttccttct ctcttccaac tacccggagg agtttgaaaa gctgctccac 5550

 caggaggagg acaactacaa cagggaactc aaagctctag agtctgaaaa 5600

 ggatgaaagg ggcaggggga gaggcagcag gataaaagga atagaaggga 5650

 aatttggcat gctggcaccc aacagggatg atgaaaatat ggacaagacc 5700

 cacctgtgct tcatccggct tctggagaat tgcattgatc aattctacgt 5750

 gtacaggaac ccagaagact acaagaggct ctttttccgt ttcatgaatg 5800

 tcctcatcaa gaggtgcaaa gaaccactca tccccagcat tggaaacaca 5850

 gtagccctcc tggagttcca gttcatccac tgtggggtgg tgctggcccg 5900

 cctctggaag aatgtcattc tatgcctccc caagagctac attgcactct 5950

 tgcactactg ggagttcctg tttagcaaga aggacaagga gcttggggat 6000

 gtgttctcca tcattcagga atacaaaccc aaggacgtga caagagccat 6050

 tcaggatttc cggttccatc tctcctacct cgccaaggtg ctatgtggct 6100

 atgagaatgt gaacttcaac gtcctgcttg atgccttcag tgaaatagac 6150

 tatgtggtct cgggtgaggc tgagcggaca ctggtgctgt gcttggtgat 6200

 gctagtgaat gctgaggaga tcctgcagcc atactgcaag cctctcctgt 6250

 atcgccactt ccgggagatt gagtcaaggc tgcagctcat gagcatggac 6300

 tgccctggcc aggttcccga gaggctcctg aaggtggtga agcgggtctt 6350

 ggtggcagtc aatgtgaagt ctgtggctga ggcactgcag gacctgctct 6400

 ttgagcggga tgaagagtac ctaatggact gtgactggcg gtgggaccct 6450

 gtgcacacca aagggtccat agtccgtggc ctctattatg aggaggtcag 6500

 actaaaccgc ctgctctgtt tggaccctgt ggactacttt gctgaacctg 6550

 agtgtgagtt tggccaggat gagatggatg aactggcatt agaagaccga 6600

 gaccacgtcc tggccaccat tctttcccaa aagcaacgga aggcctccat 6650

 acagcggaag ttgaggaggg catgcctggt ggtgtctctg tgcatcagtt 6700

 ggaggagaag agtgggcacc cagatggagc gtgtcaggga ggaggccagg 6750

 gagcccaggg ctgggaactt caaaaaggca gacgtggaca ggacccagtg 6800

 tgacctatgt ggagtgaagt ttacccgtgg cccagagaac tatttcagcc 6850

 ccagcaaagc gtttgagggg gcagcttccg aggtggcagt cctttccagg 6900

 gctgagctgg aaagggagga gtgtcaggag aggaacagcg agtcttacga 6950

 gcagcatatc catctagaac accaccagag gcagcaagtg gcctaccaga 7000

 aatactcaga atttttccac gagaaggtgg acccggccat tgatgaaggc 7050

 aagctggtgg tgcaggacat cgagcaaagt gtatggatcc acagtcacgt 7100

 gggctccaag gagcacagcc acatgctgca gaaggtccag gagcacatca 7150

 agagggtttc ggatatggtg gaggacctct acaggcggaa ggcctgggct 7200

 ggcgcggagg aggcgatgac tcggctggtc aacattctga tcctgtcagt 7250

 cagggatgca cgagactggt tgatgaaaac agagacccgc ttaaagaagg 7300

 aaggtattgt tcaggaagat gattatgaaa atgaagttga agactttggt 7350

 gagcttcggc ctagaaggcg ttctcggaaa tgtggaaagc agagaaaata 7400

 ctaatgtcca cacagctgca gcctcctcat ccttcggaac attccattct 7450

 gacttagaat tctgagcgct ggggcagaag acaaaaagaa tgtgaattag 7500

 cattttaaaa ataggggagt ctaacaacac cattgctttt tattctcatt 7550

 acttctcttt cagtggctta ggatctgatt gctccctcac ctctaaagtg 7600

 tttccaagta gagtctggca gtattagttt cccccacaaa caaattcagg 7650

 tagagaagtt gtagtcgaag ggaatgttgg gactcctcac tgcatggtcc 7700

 ctggggtgtc tggctcatcc ccatcatgac gtgagttggt agcagaggac 7750

 taggtgttag gacagactct cctcacctca gttgctgctg ctctgggcca 7800

 ggaaatctct ctatggattc cctcatctcc tgccacactg ctgcagcatc 7850

 aagtgtgcta tgagagctgt atgtgcccag gggtgggccc tgccactggc 7900

 caccccgagc ccaggacgca ttctggtcat ctctgagccc acttgtagtg 7950

 tagcttcttc tgttagagat gttagccttt tctctctgtg gcgacttttc 8000

 tgccttccct tcttctgttt tttgtgatca ttcttagcta cctgtgccaa 8050

 gtcacagtta gactacctca gaatgtagtc aagaattcac ccagtgttct 8100

 ttggatgtcc cttccctagg gggaaaggct ggggaatgtt gctgggagca 8150

 ttcccagctg cctctccaaa gtggtcctaa ctctgccttg gctatggtgc 8200

 agacattcca aaaagtgttt tgtatacagc cctgtacatc tagttttctt 8250

 ggttctccct ggcaagttcg ctaccctagc ttaggctgac gttctgatga 8300

 gtctctgctt gctgagctca tcactgtggg atggtgacct gcagagctgc 8350

 agattggagc aagtggacag aggagggagc cagctaagcc aaatccgtca 8400

 ctgccacttg gctggcaggc cttataagag ggcggatctg ggcccgtttg 8450

 caggaggcca ttgcctaccc tctccccaca gtgagccagc agccatcagc 8500

 tgatcccacc tgggaaacct tcatgcctct ctgatggtta ctgcccaccc 8550

 ttaccccacc cctcagctca gcctggtatg gaaagcaagg tgcacgttgg 8600

 tctttgattg ttctgtcctc acagcagagc cagctttccc cccatgttgc 8650

 tgctgctttt gctgctcatg ctgcttgttg ttttctcttc cttatctttc 8700

 caaattgttt ccttgaaatg cttgtttcca atttttctta gattatgttt 8750

 ctaattttta ttccaggtgt ttttttttct tacttgacag aaaaaaagaa 8800

 aaccccaaca atatcttgct gtattatcac attttttata aagttaaagc 8850

 atttctctt 8859

<210> 2761
<211> 1347
<212> PRT
<213> Homo sapien

<400> 2761
 Gly Ser Pro Lys Arg Gly Arg Ala Tyr Lys Glu Trp Lys Ile Ile
   1               5                  10                  15

 Ser Ser Phe Thr Pro Thr Ser Thr Asp Ser Arg Glu Glu Asn Arg
                  20                  25                  30

 Pro Leu Val Glu Val Pro Leu Asp Lys Pro Gly Ser Ser Gln Gly
                  35                  40                  45

 Arg Ser Leu Met Val Asn Pro Glu Met Tyr Lys Leu Leu Asn Gly
                  50                  55                  60

 Glu Leu Lys Gln Leu Tyr Thr Ala Ile Thr Arg Ala Arg Val Asn
                  65                  70                  75

 Leu Trp Ile Phe Asp Glu Asn Arg Glu Lys Arg Ala Pro Ala Phe
                  80                  85                  90

 Lys Tyr Phe Ile Arg Arg Asp Phe Val Gln Val Val Lys Thr Asp
                  95                 100                 105

 Glu Asn Lys Asp Phe Asp Asp Ser Met Phe Val Lys Thr Ser Thr
                 110                 115                 120

 Pro Ala Glu Trp Ile Ala Gln Gly Asp Tyr Tyr Ala Lys His Gln
                 125                 130                 135

 Cys Trp Lys Val Ala Ala Lys Cys Tyr Gln Lys Gly Gly Ala Phe
                 140                 145                 150

 Glu Lys Glu Lys Leu Ala Leu Ala His Asp Thr Ala Leu Ser Met
                 155                 160                 165

 Lys Ser Lys Lys Val Ser Pro Lys Glu Lys Gln Leu Glu Tyr Leu
                 170                 175                 180

 Glu Leu Ala Lys Thr Tyr Leu Glu Cys Lys Glu Pro Thr Leu Ser
                 185                 190                 195

 Leu Lys Cys Leu Ser Tyr Ala Lys Glu Phe Gln Leu Ser Ala Gln
                 200                 205                 210

 Leu Cys Glu Arg Leu Gly Lys Ile Arg Asp Ala Ala Tyr Phe Tyr
                 215                 220                 225

 Lys Arg Ser Gln Cys Tyr Lys Asp Ala Phe Arg Cys Phe Glu Gln
                 230                 235                 240

 Ile Gln Glu Phe Asp Leu Ala Leu Lys Met Tyr Cys Gln Glu Glu
                 245                 250                 255

 Leu Phe Glu Glu Ala Ala Ile Ala Val Glu Lys Tyr Glu Glu Met
                 260                 265                 270

 Leu Lys Thr Lys Thr Leu Pro Ile Ser Lys Leu Ser Tyr Ser Ala
                 275                 280                 285

 Ser Gln Phe Tyr Leu Glu Ala Ala Ala Lys Tyr Leu Ser Ala Asn
                 290                 295                 300

 Lys Met Lys Glu Met Met Ala Val Leu Ser Lys Leu Asp Ile Glu
                 305                 310                 315

 Asp Gln Leu Val Phe Leu Lys Ser Arg Lys Arg Leu Ala Glu Ala
                 320                 325                 330

 Ala Asp Leu Leu Asn Arg Glu Gly Arg Arg Glu Glu Ala Ala Leu
                 335                 340                 345

 Leu Met Lys Gln His Gly Cys Leu Leu Glu Ala Ala Arg Leu Thr
                 350                 355                 360

 Ala Asp Lys Asp Phe Gln Ala Ser Cys Leu Leu Gly Ala Ala Arg
                 365                 370                 375

 Leu Asn Val Ala Arg Asp Ser Asp Ile Glu His Thr Lys Asp Ile
                 380                 385                 390

 Leu Arg Glu Ala Leu Asp Ile Cys Tyr Gln Thr Gly Gln Leu Ser
                 395                 400                 405

 Gly Ile Ala Glu Ala His Phe Leu Gln Gly Val Ile Leu Arg Asp
                 410                 415                 420

 Phe Gln Lys Leu Arg Asp Ala Phe Phe Lys Phe Asp Thr Leu Asn
                 425                 430                 435

 His Ser Ala Gly Val Val Glu Ala Leu Tyr Glu Ala Ala Ser Gln
                 440                 445                 450

 Cys Glu Ala Glu Pro Glu Lys Ile Leu Gly Leu Ala Pro Gly Gly
                 455                 460                 465

 Leu Glu Ile Leu Leu Ser Leu Val Arg Ala Leu Lys Arg Val Thr
                 470                 475                 480

 Asn Asn Ala Glu Lys Glu Met Val Lys Ser Cys Phe Glu Phe Phe
                 485                 490                 495

 Gly Ile Ser Gln Val Asp Ala Lys Tyr Cys Gln Ile Ala Gln Asn
                 500                 505                 510

 Asp Pro Gly Pro Ile Leu Arg Ile Ile Phe Asp Leu Asp Leu Asn
                 515                 520                 525

 Leu Arg Glu Lys Lys Thr Lys Asp His Phe Leu Ile Met Thr Asp
                 530                 535                 540

 Gln Val Lys Leu Ala Leu Asn Lys His Leu Leu Gly Arg Leu Cys
                 545                 550                 555

 Gln Ile Thr Arg Ser Leu Leu Gly Lys Thr Tyr Arg Gly Val Cys
                 560                 565                 570

 Met Arg Phe Ile Val Gly Leu Lys Cys Glu Asp Glu Asn Cys Glu
                 575                 580                 585

 His Phe His Arg Pro Leu Arg Arg Cys Glu Ala Lys Cys Leu Val
                 590                 595                 600

 Gln Ser Lys Met Asn Leu Val Ala Ile Asn Gly Leu Leu Leu Glu
                 605                 610                 615

 Ala Lys Lys Val Phe Pro Lys Ile Leu Ala Glu Glu Leu Lys Glu
                 620                 625                 630

 Ile Asp Tyr Ile Leu Ser Thr Asp Met Tyr Gly Leu Cys Lys Ser
                 635                 640                 645

 Ile Leu Asp Val Leu Phe Pro Lys His Phe His Gln Arg Val Leu
                 650                 655                 660

 Ser Glu Asn Pro Met Ala Cys Lys Glu Ile Leu Lys Pro Asn Tyr
                 665                 670                 675

 Lys Ser Phe Arg Phe Tyr Arg Phe Ala Leu Lys Glu Tyr Ile His
                 680                 685                 690

 Phe Leu Phe Glu Asn Glu Ser Ala Arg Asn Arg Arg Glu Ser Thr
                 695                 700                 705

 Asp Leu Trp Leu Ser Ala Met Gln Ala Phe Leu Leu Ser Ser Asn
                 710                 715                 720

 Tyr Pro Glu Glu Phe Glu Lys Leu Leu His Gln Glu Glu Asp Asn
                 725                 730                 735

 Tyr Asn Arg Glu Leu Lys Ala Leu Glu Ser Glu Lys Asp Glu Arg
                 740                 745                 750

 Gly Arg Gly Arg Gly Ser Arg Ile Lys Gly Ile Glu Gly Lys Phe
                 755                 760                 765

 Gly Met Leu Ala Pro Asn Arg Asp Asp Glu Asn Met Asp Lys Thr
                 770                 775                 780

 His Leu Cys Phe Ile Arg Leu Leu Glu Asn Cys Ile Asp Gln Phe
                 785                 790                 795

 Tyr Val Tyr Arg Asn Pro Glu Asp Tyr Lys Arg Leu Phe Phe Arg
                 800                 805                 810

 Phe Met Asn Val Leu Ile Lys Arg Cys Lys Glu Pro Leu Ile Pro
                 815                 820                 825

 Ser Ile Gly Asn Thr Val Ala Leu Leu Glu Phe Gln Phe Ile His
                 830                 835                 840

 Cys Gly Val Val Leu Ala Arg Leu Trp Lys Asn Val Ile Leu Cys
                 845                 850                 855

 Leu Pro Lys Ser Tyr Ile Ala Leu Leu His Tyr Trp Glu Phe Leu
                 860                 865                 870

 Phe Ser Lys Lys Asp Lys Glu Leu Gly Asp Val Phe Ser Ile Ile
                 875                 880                 885

 Gln Glu Tyr Lys Pro Lys Asp Val Thr Arg Ala Ile Gln Asp Phe
                 890                 895                 900

 Arg Phe His Leu Ser Tyr Leu Ala Lys Val Leu Cys Gly Tyr Glu
                 905                 910                 915

 Asn Val Asn Phe Asn Val Leu Leu Asp Ala Phe Ser Glu Ile Asp
                 920                 925                 930

 Tyr Val Val Ser Gly Glu Ala Glu Arg Thr Leu Val Leu Cys Leu
                 935                 940                 945

 Val Met Leu Val Asn Ala Glu Glu Ile Leu Gln Pro Tyr Cys Lys
                 950                 955                 960

 Pro Leu Leu Tyr Arg His Phe Arg Glu Ile Glu Ser Arg Leu Gln
                 965                 970                 975

 Leu Met Ser Met Asp Cys Pro Gly Gln Val Pro Glu Arg Leu Leu
                 980                 985                 990

 Lys Val Val Lys Arg Val Leu Val Ala Val Asn Val Lys Ser Val
                 995                1000                1005

 Ala Glu Ala Leu Gln Asp Leu Leu Phe Glu Arg Asp Glu Glu Tyr
                1010                1015                1020

 Leu Met Asp Cys Asp Trp Arg Trp Asp Pro Val His Thr Lys Gly
                1025                1030                1035

 Ser Ile Val Arg Gly Leu Tyr Tyr Glu Glu Val Arg Leu Asn Arg
                1040                1045                1050

 Leu Leu Cys Leu Asp Pro Val Asp Tyr Phe Ala Glu Pro Glu Cys
                1055                1060                1065

 Glu Phe Gly Gln Asp Glu Met Asp Glu Leu Ala Leu Glu Asp Arg
                1070                1075                1080

 Asp His Val Leu Ala Thr Ile Leu Ser Gln Lys Gln Arg Lys Ala
                1085                1090                1095

 Ser Ile Gln Arg Lys Leu Arg Arg Ala Cys Leu Val Val Ser Leu
                1100                1105                1110

 Cys Ile Ser Trp Arg Arg Arg Val Gly Thr Gln Met Glu Arg Val
                1115                1120                1125

 Arg Glu Glu Ala Arg Glu Pro Arg Ala Gly Asn Phe Lys Lys Ala
                1130                1135                1140

 Asp Val Asp Arg Thr Gln Cys Asp Leu Cys Gly Val Lys Phe Thr
                1145                1150                1155

 Arg Gly Pro Glu Asn Tyr Phe Ser Pro Ser Lys Ala Phe Glu Gly
                1160                1165                1170

 Ala Ala Ser Glu Val Ala Val Leu Ser Arg Ala Glu Leu Glu Arg
                1175                1180                1185

 Glu Glu Cys Gln Glu Arg Asn Ser Glu Ser Tyr Glu Gln His Ile
                1190                1195                1200

 His Leu Glu His His Gln Arg Gln Gln Val Ala Tyr Gln Lys Tyr
                1205                1210                1215

 Ser Glu Phe Phe His Glu Lys Val Asp Pro Ala Ile Asp Glu Gly
                1220                1225                1230

 Lys Leu Val Val Gln Asp Ile Glu Gln Ser Val Trp Ile His Ser
                1235                1240                1245

 His Val Gly Ser Lys Glu His Ser His Met Leu Gln Lys Val Gln
                1250                1255                1260

 Glu His Ile Lys Arg Val Ser Asp Met Val Glu Asp Leu Tyr Arg
                1265                1270                1275

 Arg Lys Ala Trp Ala Gly Ala Glu Glu Ala Met Thr Arg Leu Val
                1280                1285                1290

 Asn Ile Leu Ile Leu Ser Val Arg Asp Ala Arg Asp Trp Leu Met
                1295                1300                1305

 Lys Thr Glu Thr Arg Leu Lys Lys Glu Gly Ile Val Gln Glu Asp
                1310                1315                1320

 Asp Tyr Glu Asn Glu Val Glu Asp Phe Gly Glu Leu Arg Pro Arg
                1325                1330                1335

 Arg Arg Ser Arg Lys Cys Gly Lys Gln Arg Lys Tyr
                1340                1345

<210> 2762
<211> 6188
<212> DNA
<213> Homo sapien

<400> 2762
 cagtgaaagc taggtgagtg cccggagtga agaaaagttg gcaggtttcc 50

 cactgatacc agctgctgtt ggtttctgaa cactcaaagc cgcaaatacc 100

 ttagggctgg gggcaatgaa cccaaggctg aattccaagt tcagaagcag 150

 cgaagtctga atttagaacc taggaactta aactgctgca ggtccaactt 200

 caagccccag ttttagacag aggcttggga aagatctgac ttctaacccg 250

 gttccccctc ccctcctccc ctcgatgctt ctcacaggaa agtacacctg 300

 gtcctgccaa atcgcactct tatatcctgg catcctatcc aggctctgcg 350

 aggatggaaa ctgcgaggca ggggagggaa gcgggctgtt tggccaccac 400

 ctccctagtg ctgcaggcga ccctgtcaca ctaactcctg gcagcccagt 450

 gaggtggacg gcaccggccc cacctgcaga tgagggaaat gaagctcgga 500

 ggagttccgt gatttgcttg cttcacactg tggtagcctg gccacgaaag 550

 aaccaggatt cccgacttcg ggattctttc caccacacac tttcgtccct 600

 aaggggtggg gggcgggggg agaataaaat aaccgcggaa aaggaaccac 650

 ttacatgtgt ctagcgcttc ctagaggcta cccaggatat gcgcccacca 700

 cccggccggg agtgcagaga tttgaagtcc aggttctacc ccgggctccg 750

 agtactactg cgtgacttta tgcgagtgtc cgccgccttc tgggcttgtt 800

 ttcccggaag caactcggcg cggatggagt gtgtgtgtgc gcgcgcgcgc 850

 gcgttatgtt gtgcgtgttg tgttaagcgt gtgcgtgttg tccgggggcg 900

 ggagggggag tagactaaca ccggggttcc ccgagtttcg gatcgcctac 950

 acgcttgttc ccatctggac cctgttaccc accaattgcg cccactataa 1000

 aaactgcccc tccgaggcaa agctgtgaac ccccgcgccc tttcccccac 1050

 ggtcccggag gatgaagtgg ggtgcaacgg agactcagct gagcgtccag 1100

 tttcgggcaa tacaaatctc tcggcttcta cgagcagcca gacgaccccg 1150

 cggaccgtcg ctcctgaact tgaccgagac gcaaacttcg gagtgttctc 1200

 aacgtggggg gcccactctc gggagaccgc ccctaaactt aagtcccctt 1250

 aggctcgccc ccacctggga cttcacagag ccaccttaag ggcggtattc 1300

 ccgccccccc ggaagtgcgg gggggtggca gcgtacttgg attctcagcc 1350

 tccagccccg cgcggtggcg gccgccggtg gatgacttcg ggccccacaa 1400

 gtggggaaac aacaaccacc cctcgcccgc acccctggcc caaaacaact 1450

 ggccaggttc cctggcctcc cgggtccctg catcccccgc atccccgtcc 1500

 gcagccgtga acttgagccc ccctccatca gaggttgcga gcgtccgccc 1550

 gctcgcggca gccaccgtca ctagacagtc aaaccccaag acgtcagccc 1600

 acaatgcacc gggcgggccg ggaaaaacgg cccggggagg ggaccgggga 1650

 agagagggcc gagaggcgtg cggcaggggg gagggtagga gaaagaaggg 1700

 cccgactgta ggagggcagc ggagcattac ctcatcccgt gagcctccgc 1750

 gggcccagag aagaatcttc tagggtggag tctccatggt gacgggcggg 1800

 cccgcccccc tgagagcgac gcgagccaat gggaaggcct tggggtgaca 1850

 tcatgggcta tttttagggg ttgactggta gcagataagt gttgagctcg 1900

 ggctggataa gggctcagag ttgcactgag tgtggctgaa gcagcgaggc 1950

 gggagtggag gtgcgcggag tcaggcagac agacagacac agccagccag 2000

 ccaggtcggc agtatagtcc gaactgcaaa tcttattttc ttttcacctt 2050

 ctctctaact gcccagagct agcgcctgtg gctcccgggc tggtgtttcg 2100

 ggagtgtcca gagagcctgg tctccagccg cccccgggag gagagccctg 2150

 ctgcccaggc gctgttgaca gcggcggaaa gcagcggtac ccacgcgccc 2200

 gccgggggaa gtcggcgagc ggctgcagca gcaaagaact ttcccggctg 2250

 ggaggaccgg agacaagtgg cacagagtcc cggagcgaac ttttgcaagc 2300

 ctttcctgcg tcttaggctt ctccacggcg gtaaagacca gaaggcggcg 2350

 gagagccacg caagagaaga aggacgtgcg ctcagcttcg ctcgcaccgg 2400

 ttgttgaact tgggcgagcg cgagccgcgg ctgccgggcg ccccctcccc 2450

 ctagcagcgg aggaggggac aagtcgtcgg agtccgggcg gccaagaccc 2500

 gccgccggcc ggccactgca gggtccgcac tgatccgctc cgcggggaga 2550

 gccgctgctc tgggaagtga gttcgcctgc ggactccgag gaaccgctgc 2600

 gcccgaagag cgctcagtga gtgaccgcga cttttcaaag ccgggtagcg 2650

 cgcgcgagtc gacaagtaag agtgcgggag gcatcttaat taaccctgcg 2700

 ctccctggag cgagctggtg aggagggcgc agcggggacg acagccagcg 2750

 ggtgcgtgcg ctcttagaga aactttccct gtcaaaggct ccggggggcg 2800

 cgggtgtccc ccgcttgcca gagccctgtt gcggccccga aacttgtgcg 2850

 cgcagcccaa actaacctca cgtgaagtga cggactgttc tatgactgca 2900

 aagatggaaa cgaccttcta tgacgatgcc ctcaacgcct cgttcctccc 2950

 gtccgagagc ggaccttatg gctacagtaa ccccaagatc ctgaaacaga 3000

 gcatgaccct gaacctggcc gacccagtgg ggagcctgaa gccgcacctc 3050

 cgcgccaaga actcggacct cctcacctcg cccgacgtgg ggctgctcaa 3100

 gctggcgtcg cccgagctgg agcgcctgat aatccagtcc agcaacgggc 3150

 acatcaccac cacgccgacc cccacccagt tcctgtgccc caagaacgtg 3200

 acagatgagc aggagggctt cgccgagggc ttcgtgcgcg ccctggccga 3250

 actgcacagc cagaacacgc tgcccagcgt cacgtcggcg gcgcagccgg 3300

 tcaacggggc aggcatggtg gctcccgcgg tagcctcggt ggcagggggc 3350

 agcggcagcg gcggcttcag cgccagcctg cacagcgagc cgccggtcta 3400

 cgcaaacctc agcaacttca acccaggcgc gctgagcagc ggcggcgggg 3450

 cgccctccta cggcgcggcc ggcctggcct ttcccgcgca accccagcag 3500

 cagcagcagc cgccgcacca cctgccccag cagatgcccg tgcagcaccc 3550

 gcggctgcag gccctgaagg aggagcctca gacagtgccc gagatgcccg 3600

 gcgagacacc gcccctgtcc cccatcgaca tggagtccca ggagcggatc 3650

 aaggcggaga ggaagcgcat gaggaaccgc atcgctgcct ccaagtgccg 3700

 aaaaaggaag ctggagagaa tcgcccggct ggaggaaaaa gtgaaaacct 3750

 tgaaagctca gaactcggag ctggcgtcca cggccaacat gctcagggaa 3800

 caggtggcac agcttaaaca gaaagtcatg aaccacgtta acagtgggtg 3850

 ccaactcatg ctaacgcagc agttgcaaac attttgaaga gagaccgtcg 3900

 ggggctgagg ggcaacgaag aaaaaaaata acacagagag acagacttga 3950

 gaacttgaca agttgcgacg gagagaaaaa agaagtgtcc gagaactaaa 4000

 gccaagggta tccaagttgg actgggttgc gtcctgacgg cgcccccagt 4050

 gtgcacgagt gggaaggact tggcgcgccc tcccttggcg tggagccagg 4100

 gagcggccgc ctgcgggctg ccccgctttg cggacgggct gtccccgcgc 4150

 gaacggaacg ttggactttt cgttaacatt gaccaagaac tgcatggacc 4200

 taacattcga tctcattcag tattaaaggg gggaggggga gggggttaca 4250

 aactgcaata gagactgtag attgcttctg tagtactcct taagaacaca 4300

 aagcgggggg agggttgggg aggggcggca ggagggaggt ttgtgagagc 4350

 gaggctgagc ctacagatga actctttctg gcctgccttc gttaactgtg 4400

 tatgtacata tatatatttt ttaatttgat gaaagctgat tactgtcaat 4450

 aaacagcttc atgcctttgt aagttatttc ttgtttgttt gtttgggtat 4500

 cctgcccagt gttgtttgta aataagagat ttggagcact ctgagtttac 4550

 catttgtaat aaagtatata atttttttat gttttgtttc tgaaaattcc 4600

 agaaaggata tttaagaaaa tacaataaac tattggaaag tactccccta 4650

 acctcttttc tgcatcatct gtagatacta gctatctagg tggagttgaa 4700

 agagttaaga atgtcgatta aaatcactct cagtgcttct tactattaag 4750

 cagtaaaaac tgttctctat tagactttag aaataaatgt acctgatgta 4800

 cctgatgcta tggtcaggtt atactcctcc tcccccagct atctatatgg 4850

 aattgcttac caaaggatag tgcgatgttt caggaggctg gaggaagggg 4900

 ggttgcagtg gagagggaca gcccactgag aagtcaaaca tttcaaagtt 4950

 tggattgtat caagtggcat gtgctgtgac catttataat gttagtagaa 5000

 attttacaat aggtgcttat tctcaaagca ggaattggtg gcagatttta 5050

 caaaagatgt atccttccaa tttggaatct tctctttgac aattcctaga 5100

 taaaaagatg gcctttgctt atgaatattt ataacagcat tcttgtcaca 5150

 ataaatgtat tcaaatacca ataacagatc ttgaattgct tccctttact 5200

 acttttttct tcccaagtta tatactgaag tttttatttt tagttgctga 5250

 ggttaacatt gctgcaatct gaagtgattt gaaaattaag aagcaaagaa 5300

 tttaggaaga gtcaaactag aagttgtgat ctgaatgaaa cagtctccca 5350

 atttcattaa ttctttccct ctttctccat ctctatctct ctctctacta 5400

 cctcaccccc aaataaaccc ctatgcctat ggaaactaac agtttagcat 5450

 tttgggtctg tctgtagctt atttcttaat ttgtttctaa aataatcaac 5500

 cttgtttaaa tatagaataa gtctcaaaag atagtaatct aatactatgg 5550

 aaaagattca caagagaaaa catgaactag tactaactca atgattacat 5600

 gcgtaaatca aacctcagct ctggggaaat gggaaacttg aattctgcct 5650

 acagatataa cttaggagat caacaaggca gtgcttaaca agggaacaat 5700

 tttttgcttg gttgcttttc ataccaagag ccagtgtgat tatcaggcag 5750

 caaaagcaat ttgatatcca ggaatatttc acaaaccact aattgagtca 5800

 gggctgtttg ctcattagca gtgttctagt acccagtagg tctgggagtg 5850

 ctaatatcct gcctgtggct gtaaatccaa atacacaaag agtttctcct 5900

 taggagtata tctaggagtg gaagagattg gacaggcttg ttagcttcgg 5950

 atcctttgta ataacacttc ttgaacaaag ggttactggg agcagagccc 6000

 agtttgccaa actgaatttg ccgatgtcag caacccggaa ggtgagatga 6050

 ttttgaccat atgtagaaat agcagaggga caataaagca ttttggggtg 6100

 gggctctgtg gaagctaaac aagagccaac tagaaaaaat aagcaggctg 6150

 gggaattaat tacctgcaaa ggtagactaa gcccagac 6188

<210> 2763
<211> 331
<212> PRT
<213> Homo sapien

<400> 2763
 Met Thr Ala Lys Met Glu Thr Thr Phe Tyr Asp Asp Ala Leu Asn
   1               5                  10                  15

 Ala Ser Phe Leu Pro Ser Glu Ser Gly Pro Tyr Gly Tyr Ser Asn
                  20                  25                  30

 Pro Lys Ile Leu Lys Gln Ser Met Thr Leu Asn Leu Ala Asp Pro
                  35                  40                  45

 Val Gly Ser Leu Lys Pro His Leu Arg Ala Lys Asn Ser Asp Leu
                  50                  55                  60

 Leu Thr Ser Pro Asp Val Gly Leu Leu Lys Leu Ala Ser Pro Glu
                  65                  70                  75

 Leu Glu Arg Leu Ile Ile Gln Ser Ser Asn Gly His Ile Thr Thr
                  80                  85                  90

 Thr Pro Thr Pro Thr Gln Phe Leu Cys Pro Lys Asn Val Thr Asp
                  95                 100                 105

 Glu Gln Glu Gly Phe Ala Glu Gly Phe Val Arg Ala Leu Ala Glu
                 110                 115                 120

 Leu His Ser Gln Asn Thr Leu Pro Ser Val Thr Ser Ala Ala Gln
                 125                 130                 135

 Pro Val Asn Gly Ala Gly Met Val Ala Pro Ala Val Ala Ser Val
                 140                 145                 150

 Ala Gly Gly Ser Gly Ser Gly Gly Phe Ser Ala Ser Leu His Ser
                 155                 160                 165

 Glu Pro Pro Val Tyr Ala Asn Leu Ser Asn Phe Asn Pro Gly Ala
                 170                 175                 180

 Leu Ser Ser Gly Gly Gly Ala Pro Ser Tyr Gly Ala Ala Gly Leu
                 185                 190                 195

 Ala Phe Pro Ala Gln Pro Gln Gln Gln Gln Gln Pro Pro His His
                 200                 205                 210

 Leu Pro Gln Gln Met Pro Val Gln His Pro Arg Leu Gln Ala Leu
                 215                 220                 225

 Lys Glu Glu Pro Gln Thr Val Pro Glu Met Pro Gly Glu Thr Pro
                 230                 235                 240

 Pro Leu Ser Pro Ile Asp Met Glu Ser Gln Glu Arg Ile Lys Ala
                 245                 250                 255

 Glu Arg Lys Arg Met Arg Asn Arg Ile Ala Ala Ser Lys Cys Arg
                 260                 265                 270

 Lys Arg Lys Leu Glu Arg Ile Ala Arg Leu Glu Glu Lys Val Lys
                 275                 280                 285

 Thr Leu Lys Ala Gln Asn Ser Glu Leu Ala Ser Thr Ala Asn Met
                 290                 295                 300

 Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Met Asn His
                 305                 310                 315

 Val Asn Ser Gly Cys Gln Leu Met Leu Thr Gln Gln Leu Gln Thr
                 320                 325                 330

 Phe


<210> 2764
<211> 2815
<212> DNA
<213> Homo sapien

<400> 2764
 gaattcggca cgagctcttc tcccctgatt caagactcct ctgctttgga 50

 ctgaagcact gcaggagttt gtgaccaaga acttcaagag tcaagacaga 100

 aggaagccaa gggagcagtg caatggattt ctcagtaaag gtagacatag 150

 agaaggaggt gacctgcccc atctgcctgg agctcctgac agaacctctg 200

 agcctagatt gtggccacag cttctgccaa gcctgcatca ctgcaaagat 250

 caaggagtca gtgatcatct caagagggga aagcagctgt cctgtgtgtc 300

 agaccagatt ccagcctggg aacctccgac ctaatcggca tctggccaac 350

 atagttgaga gagtcaaaga ggtcaagatg agcccacagg aggggcagaa 400

 gagagatgtc tgtgagcacc atggaaaaaa actccagatc ttctgtaagg 450

 aggatggaaa agtcatttgc tgggtttgtg aactgtctca ggaacaccaa 500

 ggtcaccaaa cattccgcat aaacgaggtg gtcaaggaat gtcaggaaaa 550

 gctgcaggta gccctgcaga ggctgataaa ggaggatcaa gaggctgaga 600

 agctggaaga tgacatcaga caagagagaa ccgcctggaa gatcgagaga 650

 cagaagattc tgaaagggtt caatgaaatg agagtcatct tggacaatga 700

 ggagcagaga gagctgcaaa agctggagga aggtgaggtg aatgtgctgg 750

 acaacctggc agcagctaca gaccagctgg tccagcagag gcaggatgcc 800

 agcacgctca tctcagatct ccagcggagg ttgacgggat cgtcagtaga 850

 gatgctgcag gatgtgattg acgtcatgaa aaggagtgaa agctggacat 900

 tgaagaagcc aaaatctgtt tccaagaaac taaagagtgt attccgagta 950

 ccagatctga gtgggatgct gcaagttctt aaagagctga cagatgtcca 1000

 gtactactgg gtggacgtga tgctgaatcc aggcagtgcc acttcgaatg 1050

 ttgctatttc tgtggatcag agacaagtga aaactgtacg cacctgcaca 1100

 tttaagaatt caaatccatg tgatttttct gcttttggtg tcttcggctg 1150

 ccaatatttc tcttcgggga aatattactg ggaagtagat gtgtctggaa 1200

 agattgcctg gatcctgggc gtacacagta aaataagtag tctgaataaa 1250

 aggaagagct ctgggtttgc ttttgatcca agtgtaaatt attcaaaagt 1300

 ttactccaga tatagacctc aatatggcta ctgggttata ggattacaga 1350

 atacatgtga atataatgct tttgaggact cctcctcttc tgatcccaag 1400

 gttttgactc tctttatggc tgtgctccct gtcgtattgg ggttttccta 1450

 gactatgagg caggcattgt ctcatttttc aatgtcacaa accacggagc 1500

 actcatctac aagttctctg gatgtcgctt ttctcgacct gcttatccgt 1550

 atttcaatcc ttggaactgc ctagtcccca tgactgtgtg cccaccgagc 1600

 tcctgagtgt tctcattcct ttacccactt ctgcatagta gcccttgtgc 1650

 tgagactcag attctgcacc tgagttcatc tctactgaga ccatctcttc 1700

 ctttctttcc ccttctttta cttagaatgt ctttgtattc atttgctagg 1750

 gcttccatag caaagcatca tagattgctg atttaaactg taattgtatt 1800

 gccgtactgt gggctggaaa tcccaaatct agattccagc agagttggtt 1850

 ctttctgagg tctgcaagga agggctctgt tccatgcctc tctccttggc 1900

 ttgtagaagg catcttgtcc ctatgactct tcacattgtc tttatgtaca 1950

 tctctgtgcc caagttttcc ctttttatta agacaccagt catactggct 2000

 cagggcccac cgctaatgcc ttaatgaaat cattttaaca ttatattctc 2050

 tacaaagacc ttatttccaa ataagataat atttggaggt attgggaata 2100

 aaatttgagg aaggcacgat ttcactcata acaatcttac cctttcttgc 2150

 aagagatgct tgtacattat tttcctaata ccttggtttc actagtagta 2200

 aacattatta ttttttttat atttgcaaag gaaacatatc taatccttcc 2250

 tatagaaaga acagtattgc tgtaattcct tttcttttct tcctcatttc 2300

 ctctgcccct taaaagattg aagaaagaga aacttgtcaa ctcatatcca 2350

 cgttatctag caaaagtcat aagaatctat cactaagtaa tgtatccttc 2400

 agaatgtgtt ggtttaccag tgacacccca tattcatcac aaaattaaag 2450

 caagaagtcc atagtaattt atttgctaat agtggatttt taatgctcag 2500

 agtttctgag gtcaaatttt atcttttcac ttacaagctc tatgatctta 2550

 aataatttac ttaatgtatt ttggtgtatt ttcctcaaat taatattggt 2600

 gttcaagact atatctaatt cctctgatca ctttgagaaa caaactttta 2650

 ttaaatgtaa ggcacttttc tatgaatttt aaatataaaa ataaatattg 2700

 ttctgattat tactgaaaag atgtcagcca tttcaatgtc ttgggaaaca 2750

 attttttgtt tttgttctgt tttctttttg cttcaataaa acaatagctg 2800

 gctctaaaaa aaaaa 2815

<210> 2765
<211> 442
<212> PRT
<213> Homo sapien

<400> 2765
 Met Asp Phe Ser Val Lys Val Asp Ile Glu Lys Glu Val Thr Cys
   1               5                  10                  15

 Pro Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys
                  20                  25                  30

 Gly His Ser Phe Cys Gln Ala Cys Ile Thr Ala Lys Ile Lys Glu
                  35                  40                  45

 Ser Val Ile Ile Ser Arg Gly Glu Ser Ser Cys Pro Val Cys Gln
                  50                  55                  60

 Thr Arg Phe Gln Pro Gly Asn Leu Arg Pro Asn Arg His Leu Ala
                  65                  70                  75

 Asn Ile Val Glu Arg Val Lys Glu Val Lys Met Ser Pro Gln Glu
                  80                  85                  90

 Gly Gln Lys Arg Asp Val Cys Glu His His Gly Lys Lys Leu Gln
                  95                 100                 105

 Ile Phe Cys Lys Glu Asp Gly Lys Val Ile Cys Trp Val Cys Glu
                 110                 115                 120

 Leu Ser Gln Glu His Gln Gly His Gln Thr Phe Arg Ile Asn Glu
                 125                 130                 135

 Val Val Lys Glu Cys Gln Glu Lys Leu Gln Val Ala Leu Gln Arg
                 140                 145                 150

 Leu Ile Lys Glu Asp Gln Glu Ala Glu Lys Leu Glu Asp Asp Ile
                 155                 160                 165

 Arg Gln Glu Arg Thr Ala Trp Lys Ile Glu Arg Gln Lys Ile Leu
                 170                 175                 180

 Lys Gly Phe Asn Glu Met Arg Val Ile Leu Asp Asn Glu Glu Gln
                 185                 190                 195

 Arg Glu Leu Gln Lys Leu Glu Glu Gly Glu Val Asn Val Leu Asp
                 200                 205                 210

 Asn Leu Ala Ala Ala Thr Asp Gln Leu Val Gln Gln Arg Gln Asp
                 215                 220                 225

 Ala Ser Thr Leu Ile Ser Asp Leu Gln Arg Arg Leu Thr Gly Ser
                 230                 235                 240

 Ser Val Glu Met Leu Gln Asp Val Ile Asp Val Met Lys Arg Ser
                 245                 250                 255

 Glu Ser Trp Thr Leu Lys Lys Pro Lys Ser Val Ser Lys Lys Leu
                 260                 265                 270

 Lys Ser Val Phe Arg Val Pro Asp Leu Ser Gly Met Leu Gln Val
                 275                 280                 285

 Leu Lys Glu Leu Thr Asp Val Gln Tyr Tyr Trp Val Asp Val Met
                 290                 295                 300

 Leu Asn Pro Gly Ser Ala Thr Ser Asn Val Ala Ile Ser Val Asp
                 305                 310                 315

 Gln Arg Gln Val Lys Thr Val Arg Thr Cys Thr Phe Lys Asn Ser
                 320                 325                 330

 Asn Pro Cys Asp Phe Ser Ala Phe Gly Val Phe Gly Cys Gln Tyr
                 335                 340                 345

 Phe Ser Ser Gly Lys Tyr Tyr Trp Glu Val Asp Val Ser Gly Lys
                 350                 355                 360

 Ile Ala Trp Ile Leu Gly Val His Ser Lys Ile Ser Ser Leu Asn
                 365                 370                 375

 Lys Arg Lys Ser Ser Gly Phe Ala Phe Asp Pro Ser Val Asn Tyr
                 380                 385                 390

 Ser Lys Val Tyr Ser Arg Tyr Arg Pro Gln Tyr Gly Tyr Trp Val
                 395                 400                 405

 Ile Gly Leu Gln Asn Thr Cys Glu Tyr Asn Ala Phe Glu Asp Ser
                 410                 415                 420

 Ser Ser Ser Asp Pro Lys Val Leu Thr Leu Phe Met Ala Val Leu
                 425                 430                 435

 Pro Val Val Leu Gly Phe Ser
                 440

<210> 2766
<211> 5338
<212> DNA
<213> Homo sapien

<400> 2766
 ggccgcgagt gcatcttcca cgaacctaat tcatctctcc agcaaaggac 50

 acatctctcc agcaaaggac acctctctcc agcaaaggac acctgcagag 100

 atgtccccag tccttcactt ctatgttcgt ccctctggcc atgagggggc 150

 agcctctgga cacactcgga ggaaactgca agggaaactg ccagagctgc 200

 agggcgtcga gactgaactg tgctacaacg tgaactggac agctgaggcc 250

 ctccccagtg ctgaggagac aaagaagctg atgtggctgt ttggttgccc 300

 cttactgctg gatgatgttg ctcgggagtc ctggctcctt cctggctcca 350

 atgacctgct gctggaggtc gggcccaggc tgaacttctc caccccaaca 400

 tccaccaaca tcgtgtcagt gtgccgcgcc actgggctgg ggcctgtgga 450

 tcgtgtggag accacccggc gctaccggct ctcgtttgcc caccccccgt 500

 cagctgaggt ggaagccatt gctctggcta ccctgcacga ccggatgaca 550

 gagcagcact tcccccatcc catccagagt ttctcccctg agagcatgcc 600

 ggaacccctc aatggcccta tcaatatact gggtgagggc cggcttgcgc 650

 tggagaaggc caaccaggag cttggtctgg ctttagactc ttgggaccta 700

 gacttctaca ccaagcgctt ccaggagcta cagcggaacc cgagcactgt 750

 ggaggccttt gacttggcgc agtccaatag cgagcacagc cgacactggt 800

 tcttcaaggg ccagctccac gtggatgggc agaagctggt gcactcactg 850

 tttgagtcca tcatgagcac ccaggaatcc tcgaacccca acaacgtcct 900

 caaattctgt gataacagca gtgcaatcca gggaaaggaa gtccgattcc 950

 tacggcctga ggaccccaca cggccaagcc gcttccagca acagcaaggg 1000

 ctgagacatg ttgtcttcac agcagagact cacaactttc ccacaggagt 1050

 atgccccttt agtggtgcaa ccactggcac agggggccgg attcgagatg 1100

 tccagtgcac aggccgcggg gcccacgtgg tggctggcac tgccggctat 1150

 tgctttggaa atctgcatat tccaggttac aatctgccct gggaggatct 1200

 aagcttccag tatcctggga attttgcccg gcccctggag gttgccattg 1250

 aagccagtaa tggagcttct gactatggca acaagtttgg ggaaccagtg 1300

 ctggctggct tcgcccgctc cttgggcctc cagctcccag acggccagcg 1350

 gcgtgagtgg atcaagccca tcatgtttag tgggggcatt gggtccatgg 1400

 aagctgacca cataagcaag gaggccccag agccaggcat ggaagttgta 1450

 aaggttggag gtcccgtcta caggattgga gttggaggtg gagctgcttc 1500

 atctgtgcag gtgcagggag ataacaccag tgacctggac tttggggctg 1550

 tgcagcgagg agacccggag atggaacaga agatgaaccg tgtgatcagg 1600

 gcttgtgtgg aggcccccaa gggaaacccc atctgcagcc ttcatgatca 1650

 gggcgctggt ggcaatggca atgtcctaaa agagctgagt gacccagctg 1700

 gagccatcat ttacaccagc cgcttccagc ttggggaccc aaccctgaat 1750

 gccctggaaa tctggggggc tgagtaccag gaatcaaatg ctcttctgct 1800

 gaggtccccc aaccgggact tcctgactca tgtcagtgcc cgtgaacgtt 1850

 gcccggcttg cttcgtgggc accatcactg gagaccggag aatagtgctg 1900

 gtggacgatc gggagtgtcc tgtcagaaga aatggccagg gggatgcccc 1950

 cccgacaccc ccgccaaccc ctgtggacct ggagctcgaa tgggtgctgg 2000

 gcaagatgcc tcggaaggag ttcttcctgc agaggaagcc ccccatgctg 2050

 cagcctctgg ccttgccccc agggctgagc gtgcaccagg ctctggagag 2100

 ggttctgagg ctgcccgccg tggccagcaa gcgctacctc accaataagg 2150

 tggaccgctc cgtgggaggc ctggtggccc agcagcagtg cgtggggccc 2200

 ctgcaaactc ctctggcaga tgtagcggtt gtggcactga gccatgagga 2250

 gctcataggg gctgccacag ccttgggaga acagccagtc aagagcctgc 2300

 tggacccaaa agtcgccgcc cggctggccg tggccgaagc cctcaccaac 2350

 ctggtgtttg ctctggtcac tgacctccgg gatgtgaagt gtagcgggaa 2400

 ctggatgtgg gcagccaagc tcccagggga gggcgcagct ttggcggatg 2450

 cctgtgaggc tatggtggca gtgatggcag ccctgggtgt ggcagtggat 2500

 ggtggcaagg actccctcag catggctgct cgggttggca ctgagaccgt 2550

 gcgggctcct gggtcactgg tcatctcagc ctatgccgtc tgcccagaca 2600

 tcacagccac tgtgacccca gacctcaagc atcctgaagg gagaggccat 2650

 ctgctctatg tggctctgag ccctgggcag caccggctcg ggggcacagc 2700

 tctggcccag tgcttctccc agcttgggga acaccctcca gacctggacc 2750

 ttcctgagaa cttggtgcgg gccttcagca tcactcaggg gctgctgaaa 2800

 gaccgcctcc tctgctcagg ccacgatgtc agtgacggag gcctcgtcac 2850

 atgcctgctg gagatggcct ttgctggaaa ttgcgggcta caggtggatg 2900

 tgcctgtccc cagggttgat gtcctgtctg tgctgttcgc tgaggagcca 2950

 ggcctcgtgc tggaggtgca ggagccagac ctggcccagg tgctgaagcg 3000

 ttaccgggat gctggcctcc attgcctgga gctgggccac acaggcgagg 3050

 ccgggcccca cgccatggtc cgggtgtcag tgaacggggc tgtggttctg 3100

 gaggagcctg ttggggagct gcgagccctc tgggaggaga cgagtttcca 3150

 gctggaccgg ctacaggcag agcctcgctg tgtggcagag gaggaacggg 3200

 gcctgaggga gcggatgggg cccagctatt gcctgccccc cacctttccc 3250

 aaagcctccg tgccccgtga gcctggtggt cccagccccc gagtcgccat 3300

 cttgcgagag gagggcagta atggagaccg ggagatggcc gatgccttcc 3350

 acttagctgg gtttgaggta tgggacgtga ccatgcagga cctctgctct 3400

 ggggcaattg ggctggacac tttccgtggc gtggccttcg tgggcggctt 3450

 cagctatgca gatgtcctgg gctctgccaa agggtgggca gctgctgtga 3500

 cctttcatcc cagggctggg gctgagctga ggcgcttccg gaagcggcca 3550

 gacaccttca gcctgggcgt gtgtaatggc tgtcaactgc tggctctgct 3600

 cggctgggtg ggaggcgacc ccaatgagga tgctgcagag atgggccctg 3650

 actcccagcc agcccggcca ggccttctgc tacgccacaa cctgtctggg 3700

 cgctacgagt ctcgctgggc cagcgtgcgt gtggggcctg ggccagccct 3750

 gatgctgcga gggatggagg gcgccgtgct gcccgtgtgg agtgcgcacg 3800

 gggaaggtta cgtagcattt tcttctccgg aactccaagc tcagattgag 3850

 gccaggggct tggctccact gcactgggct gatgatgacg ggaaccccac 3900

 agagcagtac cctctgaatc ccaatgggtc cccagggggc gtggctggca 3950

 tctgctcctg tgatggccgc cacctggctg tcatgcctca ccctgagcgg 4000

 gccgttaggc cttggcagtg ggcatggcga ccccctccat ttgatactct 4050

 gaccacctcc ccctggctcc agctctctat caatgcccga aactggaccc 4100

 tggaagggag ctgctgactg gccacagggg ctcacctggg ccccatggct 4150

 tttcacctaa gtgggtcctg ccccctcccc catgaccttc aggagcaccc 4200

 catattattt ccaaaaatat cttggacaga caaggaccaa aatgccaaaa 4250

 tctcagcgga ctcgatgatc tgcctgctga tgttccttct gtggctgtgt 4300

 ctattttcag ttctgctcta acatggcatg ccctttctca gcccaggaaa 4350

 cagcatgtgg ttcagagaaa agagcgacaa ggaaaagtta ggactcctga 4400

 ggtccgaaca ggggcttctg ttgcccactt cacaacaccc agtgatcacc 4450

 ggtgtgcaat tgcctccttg gctctgaggg atgttttgcg ctcccttttc 4500

 tcatcattgg ggttagcggg tgcagacaaa ttcagcaata gtatgcagat 4550

 cagcccctca ccacctcatt gttctcatct ggaactgaaa ctttctggat 4600

 ttctcttgaa gtgctacact gcactgaatg taaggaattg ttgcttgtgg 4650

 aagtttctca gcgtttctgg ctgtcttagg gctggcctca gaacccagca 4700

 ttcctgttat ttgcttctaa attagcagct ctcttttttt tttttttttt 4750

 gaggcagtct cactctgtca cccaggctgg agtgcagtgg cgtgatctcg 4800

 gcccactgca acctctgcct cctgggttca agcaattttc ctgcctcagc 4850

 ctcccgagta gctgggagta caggcacaca ccaccacacc cagctaattt 4900

 ttgtattttt agtagagata gggtttcacc gtgtctccca ggctggtctc 4950

 aaactcctaa cctcaagtga ttcgcctgcc tcggcctccc aaagtgctgg 5000

 gattacaggt gggagccact acagctggcc cagcagctct gtttctgata 5050

 gaggtggttg gggctctcat ccctagatcc taacccttta gtatgctgga 5100

 attctactct tcacttactg cattgactgt tgttgattag ttattattgc 5150

 aaagcactgc caccggcctc agggagttta tgtgtaatag aattaaaaat 5200

 aatagctgtg tataacactt agctcaagcc acgcatgtgt gaggcatttg 5250

 gtatgtatct gaattaattc tcactaaaat tcagcaaagg acttgatagc 5300

 ctctccccgc cttttcaata aaggatgaat gaaggttg 5338

<210> 2767
<211> 1371
<212> PRT
<213> Homo sapien

<400> 2767
 Ala Ala Ser Ala Ser Ser Thr Asn Leu Ile His Leu Ser Ser Lys
   1               5                  10                  15

 Gly His Ile Ser Pro Ala Lys Asp Thr Ser Leu Gln Gln Arg Thr
                  20                  25                  30

 Pro Ala Glu Met Ser Pro Val Leu His Phe Tyr Val Arg Pro Ser
                  35                  40                  45

 Gly His Glu Gly Ala Ala Ser Gly His Thr Arg Arg Lys Leu Gln
                  50                  55                  60

 Gly Lys Leu Pro Glu Leu Gln Gly Val Glu Thr Glu Leu Cys Tyr
                  65                  70                  75

 Asn Val Asn Trp Thr Ala Glu Ala Leu Pro Ser Ala Glu Glu Thr
                  80                  85                  90

 Lys Lys Leu Met Trp Leu Phe Gly Cys Pro Leu Leu Leu Asp Asp
                  95                 100                 105

 Val Ala Arg Glu Ser Trp Leu Leu Pro Gly Ser Asn Asp Leu Leu
                 110                 115                 120

 Leu Glu Val Gly Pro Arg Leu Asn Phe Ser Thr Pro Thr Ser Thr
                 125                 130                 135

 Asn Ile Val Ser Val Cys Arg Ala Thr Gly Leu Gly Pro Val Asp
                 140                 145                 150

 Arg Val Glu Thr Thr Arg Arg Tyr Arg Leu Ser Phe Ala His Pro
                 155                 160                 165

 Pro Ser Ala Glu Val Glu Ala Ile Ala Leu Ala Thr Leu His Asp
                 170                 175                 180

 Arg Met Thr Glu Gln His Phe Pro His Pro Ile Gln Ser Phe Ser
                 185                 190                 195

 Pro Glu Ser Met Pro Glu Pro Leu Asn Gly Pro Ile Asn Ile Leu
                 200                 205                 210

 Gly Glu Gly Arg Leu Ala Leu Glu Lys Ala Asn Gln Glu Leu Gly
                 215                 220                 225

 Leu Ala Leu Asp Ser Trp Asp Leu Asp Phe Tyr Thr Lys Arg Phe
                 230                 235                 240

 Gln Glu Leu Gln Arg Asn Pro Ser Thr Val Glu Ala Phe Asp Leu
                 245                 250                 255

 Ala Gln Ser Asn Ser Glu His Ser Arg His Trp Phe Phe Lys Gly
                 260                 265                 270

 Gln Leu His Val Asp Gly Gln Lys Leu Val His Ser Leu Phe Glu
                 275                 280                 285

 Ser Ile Met Ser Thr Gln Glu Ser Ser Asn Pro Asn Asn Val Leu
                 290                 295                 300

 Lys Phe Cys Asp Asn Ser Ser Ala Ile Gln Gly Lys Glu Val Arg
                 305                 310                 315

 Phe Leu Arg Pro Glu Asp Pro Thr Arg Pro Ser Arg Phe Gln Gln
                 320                 325                 330

 Gln Gln Gly Leu Arg His Val Val Phe Thr Ala Glu Thr His Asn
                 335                 340                 345

 Phe Pro Thr Gly Val Cys Pro Phe Ser Gly Ala Thr Thr Gly Thr
                 350                 355                 360

 Gly Gly Arg Ile Arg Asp Val Gln Cys Thr Gly Arg Gly Ala His
                 365                 370                 375

 Val Val Ala Gly Thr Ala Gly Tyr Cys Phe Gly Asn Leu His Ile
                 380                 385                 390

 Pro Gly Tyr Asn Leu Pro Trp Glu Asp Leu Ser Phe Gln Tyr Pro
                 395                 400                 405

 Gly Asn Phe Ala Arg Pro Leu Glu Val Ala Ile Glu Ala Ser Asn
                 410                 415                 420

 Gly Ala Ser Asp Tyr Gly Asn Lys Phe Gly Glu Pro Val Leu Ala
                 425                 430                 435

 Gly Phe Ala Arg Ser Leu Gly Leu Gln Leu Pro Asp Gly Gln Arg
                 440                 445                 450

 Arg Glu Trp Ile Lys Pro Ile Met Phe Ser Gly Gly Ile Gly Ser
                 455                 460                 465

 Met Glu Ala Asp His Ile Ser Lys Glu Ala Pro Glu Pro Gly Met
                 470                 475                 480

 Glu Val Val Lys Val Gly Gly Pro Val Tyr Arg Ile Gly Val Gly
                 485                 490                 495

 Gly Gly Ala Ala Ser Ser Val Gln Val Gln Gly Asp Asn Thr Ser
                 500                 505                 510

 Asp Leu Asp Phe Gly Ala Val Gln Arg Gly Asp Pro Glu Met Glu
                 515                 520                 525

 Gln Lys Met Asn Arg Val Ile Arg Ala Cys Val Glu Ala Pro Lys
                 530                 535                 540

 Gly Asn Pro Ile Cys Ser Leu His Asp Gln Gly Ala Gly Gly Asn
                 545                 550                 555

 Gly Asn Val Leu Lys Glu Leu Ser Asp Pro Ala Gly Ala Ile Ile
                 560                 565                 570

 Tyr Thr Ser Arg Phe Gln Leu Gly Asp Pro Thr Leu Asn Ala Leu
                 575                 580                 585

 Glu Ile Trp Gly Ala Glu Tyr Gln Glu Ser Asn Ala Leu Leu Leu
                 590                 595                 600

 Arg Ser Pro Asn Arg Asp Phe Leu Thr His Val Ser Ala Arg Glu
                 605                 610                 615

 Arg Cys Pro Ala Cys Phe Val Gly Thr Ile Thr Gly Asp Arg Arg
                 620                 625                 630

 Ile Val Leu Val Asp Asp Arg Glu Cys Pro Val Arg Arg Asn Gly
                 635                 640                 645

 Gln Gly Asp Ala Pro Pro Thr Pro Pro Pro Thr Pro Val Asp Leu
                 650                 655                 660

 Glu Leu Glu Trp Val Leu Gly Lys Met Pro Arg Lys Glu Phe Phe
                 665                 670                 675

 Leu Gln Arg Lys Pro Pro Met Leu Gln Pro Leu Ala Leu Pro Pro
                 680                 685                 690

 Gly Leu Ser Val His Gln Ala Leu Glu Arg Val Leu Arg Leu Pro
                 695                 700                 705

 Ala Val Ala Ser Lys Arg Tyr Leu Thr Asn Lys Val Asp Arg Ser
                 710                 715                 720

 Val Gly Gly Leu Val Ala Gln Gln Gln Cys Val Gly Pro Leu Gln
                 725                 730                 735

 Thr Pro Leu Ala Asp Val Ala Val Val Ala Leu Ser His Glu Glu
                 740                 745                 750

 Leu Ile Gly Ala Ala Thr Ala Leu Gly Glu Gln Pro Val Lys Ser
                 755                 760                 765

 Leu Leu Asp Pro Lys Val Ala Ala Arg Leu Ala Val Ala Glu Ala
                 770                 775                 780

 Leu Thr Asn Leu Val Phe Ala Leu Val Thr Asp Leu Arg Asp Val
                 785                 790                 795

 Lys Cys Ser Gly Asn Trp Met Trp Ala Ala Lys Leu Pro Gly Glu
                 800                 805                 810

 Gly Ala Ala Leu Ala Asp Ala Cys Glu Ala Met Val Ala Val Met
                 815                 820                 825

 Ala Ala Leu Gly Val Ala Val Asp Gly Gly Lys Asp Ser Leu Ser
                 830                 835                 840

 Met Ala Ala Arg Val Gly Thr Glu Thr Val Arg Ala Pro Gly Ser
                 845                 850                 855

 Leu Val Ile Ser Ala Tyr Ala Val Cys Pro Asp Ile Thr Ala Thr
                 860                 865                 870

 Val Thr Pro Asp Leu Lys His Pro Glu Gly Arg Gly His Leu Leu
                 875                 880                 885

 Tyr Val Ala Leu Ser Pro Gly Gln His Arg Leu Gly Gly Thr Ala
                 890                 895                 900

 Leu Ala Gln Cys Phe Ser Gln Leu Gly Glu His Pro Pro Asp Leu
                 905                 910                 915

 Asp Leu Pro Glu Asn Leu Val Arg Ala Phe Ser Ile Thr Gln Gly
                 920                 925                 930

 Leu Leu Lys Asp Arg Leu Leu Cys Ser Gly His Asp Val Ser Asp
                 935                 940                 945

 Gly Gly Leu Val Thr Cys Leu Leu Glu Met Ala Phe Ala Gly Asn
                 950                 955                 960

 Cys Gly Leu Gln Val Asp Val Pro Val Pro Arg Val Asp Val Leu
                 965                 970                 975

 Ser Val Leu Phe Ala Glu Glu Pro Gly Leu Val Leu Glu Val Gln
                 980                 985                 990

 Glu Pro Asp Leu Ala Gln Val Leu Lys Arg Tyr Arg Asp Ala Gly
                 995                1000                1005

 Leu His Cys Leu Glu Leu Gly His Thr Gly Glu Ala Gly Pro His
                1010                1015                1020

 Ala Met Val Arg Val Ser Val Asn Gly Ala Val Val Leu Glu Glu
                1025                1030                1035

 Pro Val Gly Glu Leu Arg Ala Leu Trp Glu Glu Thr Ser Phe Gln
                1040                1045                1050

 Leu Asp Arg Leu Gln Ala Glu Pro Arg Cys Val Ala Glu Glu Glu
                1055                1060                1065

 Arg Gly Leu Arg Glu Arg Met Gly Pro Ser Tyr Cys Leu Pro Pro
                1070                1075                1080

 Thr Phe Pro Lys Ala Ser Val Pro Arg Glu Pro Gly Gly Pro Ser
                1085                1090                1095

 Pro Arg Val Ala Ile Leu Arg Glu Glu Gly Ser Asn Gly Asp Arg
                1100                1105                1110

 Glu Met Ala Asp Ala Phe His Leu Ala Gly Phe Glu Val Trp Asp
                1115                1120                1125

 Val Thr Met Gln Asp Leu Cys Ser Gly Ala Ile Gly Leu Asp Thr
                1130                1135                1140

 Phe Arg Gly Val Ala Phe Val Gly Gly Phe Ser Tyr Ala Asp Val
                1145                1150                1155

 Leu Gly Ser Ala Lys Gly Trp Ala Ala Ala Val Thr Phe His Pro
                1160                1165                1170

 Arg Ala Gly Ala Glu Leu Arg Arg Phe Arg Lys Arg Pro Asp Thr
                1175                1180                1185

 Phe Ser Leu Gly Val Cys Asn Gly Cys Gln Leu Leu Ala Leu Leu
                1190                1195                1200

 Gly Trp Val Gly Gly Asp Pro Asn Glu Asp Ala Ala Glu Met Gly
                1205                1210                1215

 Pro Asp Ser Gln Pro Ala Arg Pro Gly Leu Leu Leu Arg His Asn
                1220                1225                1230

 Leu Ser Gly Arg Tyr Glu Ser Arg Trp Ala Ser Val Arg Val Gly
                1235                1240                1245

 Pro Gly Pro Ala Leu Met Leu Arg Gly Met Glu Gly Ala Val Leu
                1250                1255                1260

 Pro Val Trp Ser Ala His Gly Glu Gly Tyr Val Ala Phe Ser Ser
                1265                1270                1275

 Pro Glu Leu Gln Ala Gln Ile Glu Ala Arg Gly Leu Ala Pro Leu
                1280                1285                1290

 His Trp Ala Asp Asp Asp Gly Asn Pro Thr Glu Gln Tyr Pro Leu
                1295                1300                1305

 Asn Pro Asn Gly Ser Pro Gly Gly Val Ala Gly Ile Cys Ser Cys
                1310                1315                1320

 Asp Gly Arg His Leu Ala Val Met Pro His Pro Glu Arg Ala Val
                1325                1330                1335

 Arg Pro Trp Gln Trp Ala Trp Arg Pro Pro Pro Phe Asp Thr Leu
                1340                1345                1350

 Thr Thr Ser Pro Trp Leu Gln Leu Ser Ile Asn Ala Arg Asn Trp
                1355                1360                1365

 Thr Leu Glu Gly Ser Cys
                1370

<210> 2768
<211> 4064
<212> DNA
<213> Homo sapien

<400> 2768
 ctgcggccgc ctggtttctt gccttaagga gcccattgcc tttcccgctg 50

 aagtctagat gttgacatgt aataaagcgg gcagcaggat ggtggtggat 100

 gcggccaact ccaatgggcc tttccagccc gtggtccttc tccatattcg 150

 agatgttcct cctgctgatc aagagaagct ttttatccag aagttacgtc 200

 agtgttgcgt cctctttgac tttgtttctg atccactaag tgacctaaag 250

 tggaaggaag taaaacgagc tgctttaagt gaaatggtag aatatatcac 300

 ccataatcgg aatgtgatca cagagcctat ttacccagaa gtagtccata 350

 tgtttgcagt taacatgttt cgaacattac caccttcctc caatcctacg 400

 ggagcggaat ttgacccgga ggaagatgaa ccaacgttag aagcagcctg 450

 gcctcatcta cagcttgttt atgaattttt cttaagattt ttagagtctc 500

 cagatttcca acctaatata gcgaagaaat atattgatca gaagtttgta 550

 ttgcagcttt tagagctctt tgacagtgaa gatcctcggg agagagattt 600

 tcttaaaacc acccttcaca gaatctatgg gaaattccta ggcttgagag 650

 cttacatcag aaaacagata aataatatat tttataggtt tatttatgaa 700

 acagagcatc ataatggcat agcagagtta ctggaaatat tgggaagtat 750

 aattaatgga tttgccttac cactaaaaga agagcacaag attttcttat 800

 tgaaggtgtt actacctttg cacaaagtga aatctctgag tgtctaccat 850

 ccccagctgg catactgtgt agtgcagttt ttagaaaagg acagcaccct 900

 cacggaacca gtggtgatgg cacttctcaa atactggcca aagactcaca 950

 gtccaaaaga agtaatgttc ttaaacgaat tagaagagat tttagatgtc 1000

 attgaaccat cagaatttgt gaagatcatg gaacccctct tccggcagtt 1050

 ggccaaatgt gtctccagcc cacacttcca ggtggcagag cgagctctct 1100

 attactggaa taatgaatac atcatgagtt taatcagtga caacgcagcg 1150

 aagattctgc ccatcatgtt tccttccttg taccgcaact caaagaccca 1200

 ttggaacaag acaatacatg gcttgatata caacgccctg aagctcttca 1250

 tggagatgaa ccaaaagcta tttgatgact gtacacaaca gttcaaagca 1300

 gagaaactaa aagagaagct aaaaatgaaa gaacgggaag aagcatgggt 1350

 taaaatagaa aatctagcca aagccaatcc ccagtacaca gtgtatagtc 1400

 aagccagcac catgagcatt ccggttgcaa tggagacaga tgggccttta 1450

 tttgaagatg tgcagatgct gagaaagaca gtgaaggacg aggctcatca 1500

 ggcacagaaa gatccgaaga aggaccgtcc tcttgcactc cgcaagtccg 1550

 agctgcctca ggacccccac accaagaaag ccttggaagc tcactgcagg 1600

 gccgatgagc tggcctccca ggacggccgc tagcctccgg ggcgccgcgt 1650

 cggggccggg cccgccagtt cttttccgga ttctgtagaa aatacatact 1700

 tcctgtgcca taccaatcag ttacactcaa agctttcttg gaccccgttc 1750

 cgtaggcaat aacgtgcgtc cgcctcagcg cgagattagg agttcaaaca 1800

 atggtgactt cccagagccc gctggcagag ccgcgggttg acgacggtgt 1850

 cctcgcagtg tcgccgccac cccagcgtag tccaagtcag actatttcac 1900

 aaagtcagag cgataggaaa gcaccctgcc cttcatcttc atgttctccc 1950

 aaatggaact taggatcttt taacataggt ggttctgtga taacatcagt 2000

 gttttccaaa tcaaaggaac gctttaaaaa ataggaccta ttttttaaga 2050

 ctttacagcc tttgaaatgg tttccacgtg attgttacgc cagcagttct 2100

 tttgtttgtt tttcaatctc agtgaaatgg ctctttgctt tcgagttctc 2150

 acgcaacgta ctgggcaaat gacaatcctc agccgctggt attttctaag 2200

 gggtctcttc actttgatga gtgacatgaa caccgtgtct ccttctcttg 2250

 tgtgtaccta aagccatatt tccaagtctg tggtactcca ggattccagg 2300

 agtaagcctg tagaagagat ttattttaaa agagattgct ctgaaattta 2350

 tcttaaaaga gcttgctctg tctaccttga cagaaattgg agttttaaaa 2400

 ttatgtgtta atatttttat ttgcagattt cgtttccgtc aacttaaaca 2450

 ttgttgccct tcaacaaggc tcttgaatta ataaaattat agtctctaag 2500

 aattccacat tttatggaaa gttagagcaa aatcattttg agttaagcca 2550

 gttcttagcc taatgcaaac tgcagcgcct ttaagcataa agtaacacaa 2600

 cagcattgca cggggccggc actgccgctg ccttcactga aggctgcagt 2650

 gctgttctga gagcttggag gaggcaccag cgaggatgac gtttagtgga 2700

 gctctttctg ttgaaaagag ctcacgttat caacaccttg taaggaaaat 2750

 acagtgtctg agttttcatc ggtcttcaca tgctgctata tattccacag 2800

 agttccttgc atgtactgag cttttgtttt agatggaata gcacaaggag 2850

 aaaaatcttt aaacttagtg ctttgtctat tctttatttc tctcagggtg 2900

 gccagtattt tgacttattt atcctgcttg aaagctactt gagatgtgta 2950

 ctgctattct aaacacgtga tctagtttct ttcatctctg gcataagatt 3000

 atataactta atgttaagtg tcttgaggca taaaagacaa aatgtggctt 3050

 attttaggat ctgttttttc atcgaggtct cgggtatcct ttcaaagata 3100

 gtgagaagca gacactgctc cttgtgcagc tctggtacct cctgcccact 3150

 gctgtcactt caagccactg gcaatgcttc tgtcctcgtg tcttggagga 3200

 aaatcacctg gggggagggg acttcttgtg gtaagagcaa gtgcaggtat 3250

 gaaatgcgaa gattgcccca gctaaaagtg gacaagtccg ctttgtgaga 3300

 tgaatacttc ctgagaaact tgacaagtat ctctccattt taccattatg 3350

 aaaactatca ttaaaaaaaa cagtttagat gccttctcct tttgagggaa 3400

 aaagggtgct ttttattgta taaagcagcg tcttatgtat tttgatatac 3450

 cattgtttga acttccgtct ttagctgata gattctcaaa tatccttgat 3500

 tttggatgtt cagtatgttt gtgagagagg tttctgggaa gactctcttt 3550

 ttgccctcgg gaaaaagcaa aatatcaatg tttgggtgac tgtgtaaagc 3600

 tcagtgtgta agaacatctt tttgtctagg ttttctttct gctctttatt 3650

 gaagacaaac actcaccaaa aagaaaaata aaagttttca gagaaactaa 3700

 ttttctttgg caagagtatt acttaatatt ttggcctcct aaagtttccc 3750

 tagttagtac tcggactcct gtgctaattg tcagcttaca tatcattgta 3800

 tagagactgt ttattctgta ccaaactgat ttcaaaagta ctacattgaa 3850

 aataaaccgg tgactgtttt tcttcataaa gttctgcgtt tggcatcttc 3900

 actctttcca aaatgtatct gtacatcaga aatgtcacta ttccaagtgt 3950

 ctttttagtg tggcctttag tatggcttcc ttttaatatt gtacatacat 4000

 tgtatctttg ttttatggta ataagtaata aaaatgtaga cttcaaaaaa 4050

 aaaagcggcc gcag 4064

<210> 2769
<211> 514
<212> PRT
<213> Homo sapien

<400> 2769
 Met Val Val Asp Ala Ala Asn Ser Asn Gly Pro Phe Gln Pro Val
   1               5                  10                  15

 Val Leu Leu His Ile Arg Asp Val Pro Pro Ala Asp Gln Glu Lys
                  20                  25                  30

 Leu Phe Ile Gln Lys Leu Arg Gln Cys Cys Val Leu Phe Asp Phe
                  35                  40                  45

 Val Ser Asp Pro Leu Ser Asp Leu Lys Trp Lys Glu Val Lys Arg
                  50                  55                  60

 Ala Ala Leu Ser Glu Met Val Glu Tyr Ile Thr His Asn Arg Asn
                  65                  70                  75

 Val Ile Thr Glu Pro Ile Tyr Pro Glu Val Val His Met Phe Ala
                  80                  85                  90

 Val Asn Met Phe Arg Thr Leu Pro Pro Ser Ser Asn Pro Thr Gly
                  95                 100                 105

 Ala Glu Phe Asp Pro Glu Glu Asp Glu Pro Thr Leu Glu Ala Ala
                 110                 115                 120

 Trp Pro His Leu Gln Leu Val Tyr Glu Phe Phe Leu Arg Phe Leu
                 125                 130                 135

 Glu Ser Pro Asp Phe Gln Pro Asn Ile Ala Lys Lys Tyr Ile Asp
                 140                 145                 150

 Gln Lys Phe Val Leu Gln Leu Leu Glu Leu Phe Asp Ser Glu Asp
                 155                 160                 165

 Pro Arg Glu Arg Asp Phe Leu Lys Thr Thr Leu His Arg Ile Tyr
                 170                 175                 180

 Gly Lys Phe Leu Gly Leu Arg Ala Tyr Ile Arg Lys Gln Ile Asn
                 185                 190                 195

 Asn Ile Phe Tyr Arg Phe Ile Tyr Glu Thr Glu His His Asn Gly
                 200                 205                 210

 Ile Ala Glu Leu Leu Glu Ile Leu Gly Ser Ile Ile Asn Gly Phe
                 215                 220                 225

 Ala Leu Pro Leu Lys Glu Glu His Lys Ile Phe Leu Leu Lys Val
                 230                 235                 240

 Leu Leu Pro Leu His Lys Val Lys Ser Leu Ser Val Tyr His Pro
                 245                 250                 255

 Gln Leu Ala Tyr Cys Val Val Gln Phe Leu Glu Lys Asp Ser Thr
                 260                 265                 270

 Leu Thr Glu Pro Val Val Met Ala Leu Leu Lys Tyr Trp Pro Lys
                 275                 280                 285

 Thr His Ser Pro Lys Glu Val Met Phe Leu Asn Glu Leu Glu Glu
                 290                 295                 300

 Ile Leu Asp Val Ile Glu Pro Ser Glu Phe Val Lys Ile Met Glu
                 305                 310                 315

 Pro Leu Phe Arg Gln Leu Ala Lys Cys Val Ser Ser Pro His Phe
                 320                 325                 330

 Gln Val Ala Glu Arg Ala Leu Tyr Tyr Trp Asn Asn Glu Tyr Ile
                 335                 340                 345

 Met Ser Leu Ile Ser Asp Asn Ala Ala Lys Ile Leu Pro Ile Met
                 350                 355                 360

 Phe Pro Ser Leu Tyr Arg Asn Ser Lys Thr His Trp Asn Lys Thr
                 365                 370                 375

 Ile His Gly Leu Ile Tyr Asn Ala Leu Lys Leu Phe Met Glu Met
                 380                 385                 390

 Asn Gln Lys Leu Phe Asp Asp Cys Thr Gln Gln Phe Lys Ala Glu
                 395                 400                 405

 Lys Leu Lys Glu Lys Leu Lys Met Lys Glu Arg Glu Glu Ala Trp
                 410                 415                 420

 Val Lys Ile Glu Asn Leu Ala Lys Ala Asn Pro Gln Tyr Thr Val
                 425                 430                 435

 Tyr Ser Gln Ala Ser Thr Met Ser Ile Pro Val Ala Met Glu Thr
                 440                 445                 450

 Asp Gly Pro Leu Phe Glu Asp Val Gln Met Leu Arg Lys Thr Val
                 455                 460                 465

 Lys Asp Glu Ala His Gln Ala Gln Lys Asp Pro Lys Lys Asp Arg
                 470                 475                 480

 Pro Leu Ala Leu Arg Lys Ser Glu Leu Pro Gln Asp Pro His Thr
                 485                 490                 495

 Lys Lys Ala Leu Glu Ala His Cys Arg Ala Asp Glu Leu Ala Ser
                 500                 505                 510

 Gln Asp Gly Arg


<210> 2770
<211> 3961
<212> DNA
<213> Homo sapien

<400> 2770
 agcgggaaac gtacctaagt attattggac agccggagta ttttacagtg 50

 gttgctgctc aggaaatttg agtgaaggac tgcaaaagag gagcaaagca 100

 gacccgagag agaaggcagc agtgctcccc tgtgacgtgc tccatcaccg 150

 ggcagggaag acaccgctgc cacctctcca cagccttgtt caagagcact 200

 ggaaattgat ggtacaaaac agaagaggga acggaaaaag acagtctcat 250

 tcagcagcat gccaacagag aagaagatca gcagtgcaag tgattgtatt 300

 aattcaatgg ttgagggttc agaactcaaa aaggttcgct ccaactctag 350

 aatttatcat aggtactttt tactggatgc tgacatgcag agcctaaggt 400

 gggagccatc taagaaggat tctgagaaag ccaagattga cattaaatcc 450

 atcaaggaag tgagaacagg aaaaaacaca gacatattcc gcagcaatgg 500

 catttctgac cggatatctg aagattgtgc gttttccgtc atatatggag 550

 agaattatga gtcactggat ttggttgcca actccgcaga tgttgcaaac 600

 atctgggtta caggactgcg gtacctaatt tcttatggaa aacatacact 650

 tgatatgtta gaaagtagcc aagataacat gaggacttct tgggtttcac 700

 aaatgtttag tgaaattgat gtagataacc ttggacatat aactctgtgt 750

 aatgctgtgc aatgtatcag aaacctcaat cctggtttaa aaacgagcaa 800

 aattgagctt aagttcaaag aattgcataa atcaaaggac aaagctggta 850

 ccgaggtcac aaaggaagaa tttattgagg tttttcatga gctttgtact 900

 agacctgaaa tttatttcct tttagttcag ttttcaagca ataaagaatt 950

 ccttgatacc aaggacctta tgatgtttct tgaggcagaa cagggtgtgg 1000

 cacatataaa tgaggaaata agccttgaaa ttattcacaa atatgaacca 1050

 tccaaagagg gtcaggaaaa gggctggctc tccatagacg ggttcactaa 1100

 ttaccttatg tcacctgact gttatatatt cgatccagaa cataagaagg 1150

 tctgtcagga tatgaagcaa cctctgtctc attactttat aaactcatct 1200

 cataatacat acttaataga ggatcagttc cgaggtccct ccgacatcac 1250

 aggatatatt cgagctctta aaatgggttg ccggagtgtt gaattagatg 1300

 tatgggatgg gccggacaat gaacctgtaa tttacacagg ccacaccatg 1350

 acctctcaga tagttttccg cagtgtcatt gatattatta acaagtatgc 1400

 attctttgct tcagagtatc ctcttatctt gtgtttagaa aaccactgtt 1450

 ccattaaaca acagaaggta atggttcagc acatgaagaa acttttagga 1500

 gacaagctct atacaacatc acccaatgtt gaggaatctt atctaccatc 1550

 cccagatgtc ctgaaaggga aaatactaat taaagcaaag aagctgtcct 1600

 caaattgctc tggggtagaa ggagatgtta ctgacgaaga tgaaggagca 1650

 gaaatgtctc agaggatggg aaaagagaac atggagcaac ccaataatgt 1700

 gcctgtgaag cgatttcagc tttgtaaaga actgtctgaa ctggtcagca 1750

 tctgcaaatc agttcagttc aaagaatttc agatgtcgtt tcaggttcag 1800

 aagtactggg aagtctgttc ctttaatgaa gtgcttgcca gcaagtacgc 1850

 caatgaaaat ccaggggact ttgtaaatta caacaaacgt tttcttgcta 1900

 gggtttttcc cagtccaatg agaattgatt ccagtaacat gaatcctcaa 1950

 gatttttgga aatgtggttg ccaaattgta gccatgaact ttcagacacc 2000

 aggactgatg atggacctga atattggctg gtttaggcag aacggaaact 2050

 gtggctatgt cctccggcca gccatcatga gggaggaggt ctccttcttc 2100

 agcgtcaata caaaagactc tgtcccaggg gtctcacctc aacttcttca 2150

 cattaaaatc atcagtgggc agaactttcc caagcccaaa ggatcaggtg 2200

 ccaaaggtga tgtggtagat ccttatgtct atgttgaaat ccatggaatc 2250

 cctgctgatt gtgcagaaca aaggacaaaa acagtgcacc agaatggaga 2300

 cgctcacatt tttgatgaaa gctttgaatt tcaaatcaac ctgcctgaac 2350

 tggccatggt gcgctttgta gtgctggatg atgactacat tggggatgaa 2400

 ttcatcggcc agtacacaat tccctttgaa tgtttacaga cgggctaccg 2450

 ccatgtcccc ctgcagtcct taactggaga ggtccttgca catgcttctt 2500

 tatttgtcca cgtggctatt actaaccgaa gaggaggagg aaagcctcgt 2550

 aaaaggggcc tttctgtgag aaaagggaag aaatccaggg aatatgcatc 2600

 tttgagaaca ctgtggatta aaaccgtgga tgaggtattc aagaatgccc 2650

 agccccctat acgggatgcc acagatctga gagaaaacat gcagaatgcg 2700

 gtggtgtcat tcaaggagct gtgtggcctc tcctctgtgg ccaatctcat 2750

 gcagtgcatg ttggcggtgt ctccccgctt tctggggccc gataacacac 2800

 ccctagtggt cctaaatctc agcgagcagt accccacaat ggagctgcag 2850

 ggaattgtgc cggaggttct gaagaagatc gtaacaactt atgacatgat 2900

 gattcagtcc ctcaaggcgt tgattgaaaa tgcagatgct gtatatgaaa 2950

 agatcgtaca ttgtcagaag gcagccatgg aattccatga acacttgcac 3000

 agcataggca ccaaggaagg tttgaaggaa agaaaactac aaaaagcagt 3050

 ggagagcttt acctggaata ttaccatctt aaagggacaa gcagatcttt 3100

 tgaaatatgc taagaatgag acattggaga acctgaaaca aatccatttt 3150

 gctgctgttt catgtggact gaataaacca ggcaccgaaa atgctgatgt 3200

 ccagaagcca cgccggagct tggaagtcat acccgaaaaa gcaaacgatg 3250

 aaactggaga atgaggaaac ttacaataaa ccattatgga gtttataact 3300

 ctaggaccaa ttgtagtcag atgggacatt tgctttgcac tcactaatga 3350

 gaataatatt cgggatttta aagcacaact ggaatagcta attacagtct 3400

 attaaaactg tgaatgtatg tagcaatcgt gcgtgtgaag gcaaataaac 3450

 tctttaacag gcaattatat tgctggccaa aatatgctat atttgtatac 3500

 aaagacattc taactcagtt ccagtatgaa gaaagattat tcactctagc 3550

 tccactgaga aacattttcc taagtgaaaa caatttctta agatggaaat 3600

 ggattggatt gtcaaattat tatttattgg agaaaaaaac ctgatctaca 3650

 catttttact tatatggggt tgccagagtc tctgggttct agatgatttt 3700

 ggtggcatgc ttgctgagcc ataattacta aagagaatgt aagtggacgg 3750

 gttccctgaa tccccggggt ccttggagag ccatcgagga gaatgtgcaa 3800

 ttggactgaa gctccctggc tgaagataca tgccgagtca gcacatgggt 3850

 agagatgatg taaaagcagc caatctggaa acaatacatt gtaaatagtt 3900

 tttcattgta tgaagtagtg ttcacattaa aaagatgttt tatgacaaaa 3950

 aaaaaaaaaa a 3961

<210> 2771
<211> 1001
<212> PRT
<213> Homo sapien

<400> 2771
 Met Pro Thr Glu Lys Lys Ile Ser Ser Ala Ser Asp Cys Ile Asn
   1               5                  10                  15

 Ser Met Val Glu Gly Ser Glu Leu Lys Lys Val Arg Ser Asn Ser
                  20                  25                  30

 Arg Ile Tyr His Arg Tyr Phe Leu Leu Asp Ala Asp Met Gln Ser
                  35                  40                  45

 Leu Arg Trp Glu Pro Ser Lys Lys Asp Ser Glu Lys Ala Lys Ile
                  50                  55                  60

 Asp Ile Lys Ser Ile Lys Glu Val Arg Thr Gly Lys Asn Thr Asp
                  65                  70                  75

 Ile Phe Arg Ser Asn Gly Ile Ser Asp Arg Ile Ser Glu Asp Cys
                  80                  85                  90

 Ala Phe Ser Val Ile Tyr Gly Glu Asn Tyr Glu Ser Leu Asp Leu
                  95                 100                 105

 Val Ala Asn Ser Ala Asp Val Ala Asn Ile Trp Val Thr Gly Leu
                 110                 115                 120

 Arg Tyr Leu Ile Ser Tyr Gly Lys His Thr Leu Asp Met Leu Glu
                 125                 130                 135

 Ser Ser Gln Asp Asn Met Arg Thr Ser Trp Val Ser Gln Met Phe
                 140                 145                 150

 Ser Glu Ile Asp Val Asp Asn Leu Gly His Ile Thr Leu Cys Asn
                 155                 160                 165

 Ala Val Gln Cys Ile Arg Asn Leu Asn Pro Gly Leu Lys Thr Ser
                 170                 175                 180

 Lys Ile Glu Leu Lys Phe Lys Glu Leu His Lys Ser Lys Asp Lys
                 185                 190                 195

 Ala Gly Thr Glu Val Thr Lys Glu Glu Phe Ile Glu Val Phe His
                 200                 205                 210

 Glu Leu Cys Thr Arg Pro Glu Ile Tyr Phe Leu Leu Val Gln Phe
                 215                 220                 225

 Ser Ser Asn Lys Glu Phe Leu Asp Thr Lys Asp Leu Met Met Phe
                 230                 235                 240

 Leu Glu Ala Glu Gln Gly Val Ala His Ile Asn Glu Glu Ile Ser
                 245                 250                 255

 Leu Glu Ile Ile His Lys Tyr Glu Pro Ser Lys Glu Gly Gln Glu
                 260                 265                 270

 Lys Gly Trp Leu Ser Ile Asp Gly Phe Thr Asn Tyr Leu Met Ser
                 275                 280                 285

 Pro Asp Cys Tyr Ile Phe Asp Pro Glu His Lys Lys Val Cys Gln
                 290                 295                 300

 Asp Met Lys Gln Pro Leu Ser His Tyr Phe Ile Asn Ser Ser His
                 305                 310                 315

 Asn Thr Tyr Leu Ile Glu Asp Gln Phe Arg Gly Pro Ser Asp Ile
                 320                 325                 330

 Thr Gly Tyr Ile Arg Ala Leu Lys Met Gly Cys Arg Ser Val Glu
                 335                 340                 345

 Leu Asp Val Trp Asp Gly Pro Asp Asn Glu Pro Val Ile Tyr Thr
                 350                 355                 360

 Gly His Thr Met Thr Ser Gln Ile Val Phe Arg Ser Val Ile Asp
                 365                 370                 375

 Ile Ile Asn Lys Tyr Ala Phe Phe Ala Ser Glu Tyr Pro Leu Ile
                 380                 385                 390

 Leu Cys Leu Glu Asn His Cys Ser Ile Lys Gln Gln Lys Val Met
                 395                 400                 405

 Val Gln His Met Lys Lys Leu Leu Gly Asp Lys Leu Tyr Thr Thr
                 410                 415                 420

 Ser Pro Asn Val Glu Glu Ser Tyr Leu Pro Ser Pro Asp Val Leu
                 425                 430                 435

 Lys Gly Lys Ile Leu Ile Lys Ala Lys Lys Leu Ser Ser Asn Cys
                 440                 445                 450

 Ser Gly Val Glu Gly Asp Val Thr Asp Glu Asp Glu Gly Ala Glu
                 455                 460                 465

 Met Ser Gln Arg Met Gly Lys Glu Asn Met Glu Gln Pro Asn Asn
                 470                 475                 480

 Val Pro Val Lys Arg Phe Gln Leu Cys Lys Glu Leu Ser Glu Leu
                 485                 490                 495

 Val Ser Ile Cys Lys Ser Val Gln Phe Lys Glu Phe Gln Met Ser
                 500                 505                 510

 Phe Gln Val Gln Lys Tyr Trp Glu Val Cys Ser Phe Asn Glu Val
                 515                 520                 525

 Leu Ala Ser Lys Tyr Ala Asn Glu Asn Pro Gly Asp Phe Val Asn
                 530                 535                 540

 Tyr Asn Lys Arg Phe Leu Ala Arg Val Phe Pro Ser Pro Met Arg
                 545                 550                 555

 Ile Asp Ser Ser Asn Met Asn Pro Gln Asp Phe Trp Lys Cys Gly
                 560                 565                 570

 Cys Gln Ile Val Ala Met Asn Phe Gln Thr Pro Gly Leu Met Met
                 575                 580                 585

 Asp Leu Asn Ile Gly Trp Phe Arg Gln Asn Gly Asn Cys Gly Tyr
                 590                 595                 600

 Val Leu Arg Pro Ala Ile Met Arg Glu Glu Val Ser Phe Phe Ser
                 605                 610                 615

 Val Asn Thr Lys Asp Ser Val Pro Gly Val Ser Pro Gln Leu Leu
                 620                 625                 630

 His Ile Lys Ile Ile Ser Gly Gln Asn Phe Pro Lys Pro Lys Gly
                 635                 640                 645

 Ser Gly Ala Lys Gly Asp Val Val Asp Pro Tyr Val Tyr Val Glu
                 650                 655                 660

 Ile His Gly Ile Pro Ala Asp Cys Ala Glu Gln Arg Thr Lys Thr
                 665                 670                 675

 Val His Gln Asn Gly Asp Ala His Ile Phe Asp Glu Ser Phe Glu
                 680                 685                 690

 Phe Gln Ile Asn Leu Pro Glu Leu Ala Met Val Arg Phe Val Val
                 695                 700                 705

 Leu Asp Asp Asp Tyr Ile Gly Asp Glu Phe Ile Gly Gln Tyr Thr
                 710                 715                 720

 Ile Pro Phe Glu Cys Leu Gln Thr Gly Tyr Arg His Val Pro Leu
                 725                 730                 735

 Gln Ser Leu Thr Gly Glu Val Leu Ala His Ala Ser Leu Phe Val
                 740                 745                 750

 His Val Ala Ile Thr Asn Arg Arg Gly Gly Gly Lys Pro Arg Lys
                 755                 760                 765

 Arg Gly Leu Ser Val Arg Lys Gly Lys Lys Ser Arg Glu Tyr Ala
                 770                 775                 780

 Ser Leu Arg Thr Leu Trp Ile Lys Thr Val Asp Glu Val Phe Lys
                 785                 790                 795

 Asn Ala Gln Pro Pro Ile Arg Asp Ala Thr Asp Leu Arg Glu Asn
                 800                 805                 810

 Met Gln Asn Ala Val Val Ser Phe Lys Glu Leu Cys Gly Leu Ser
                 815                 820                 825

 Ser Val Ala Asn Leu Met Gln Cys Met Leu Ala Val Ser Pro Arg
                 830                 835                 840

 Phe Leu Gly Pro Asp Asn Thr Pro Leu Val Val Leu Asn Leu Ser
                 845                 850                 855

 Glu Gln Tyr Pro Thr Met Glu Leu Gln Gly Ile Val Pro Glu Val
                 860                 865                 870

 Leu Lys Lys Ile Val Thr Thr Tyr Asp Met Met Ile Gln Ser Leu
                 875                 880                 885

 Lys Ala Leu Ile Glu Asn Ala Asp Ala Val Tyr Glu Lys Ile Val
                 890                 895                 900

 His Cys Gln Lys Ala Ala Met Glu Phe His Glu His Leu His Ser
                 905                 910                 915

 Ile Gly Thr Lys Glu Gly Leu Lys Glu Arg Lys Leu Gln Lys Ala
                 920                 925                 930

 Val Glu Ser Phe Thr Trp Asn Ile Thr Ile Leu Lys Gly Gln Ala
                 935                 940                 945

 Asp Leu Leu Lys Tyr Ala Lys Asn Glu Thr Leu Glu Asn Leu Lys
                 950                 955                 960

 Gln Ile His Phe Ala Ala Val Ser Cys Gly Leu Asn Lys Pro Gly
                 965                 970                 975

 Thr Glu Asn Ala Asp Val Gln Lys Pro Arg Arg Ser Leu Glu Val
                 980                 985                 990

 Ile Pro Glu Lys Ala Asn Asp Glu Thr Gly Glu
                 995                1000

<210> 2772
<211> 1404
<212> DNA
<213> Homo sapien

<400> 2772
 ggaagagtta tagaccgcta acacctgtca ctggccactg gtttcccgga 50

 gttagcggca acgaccttgc agcctggaca ctagccaggc gctccctctt 100

 ctcacagcgg cccacgtctc cttgcttggg agcccatcgt cctggctccg 150

 gtggcctcgc tgggtctcgg ggaagcagag gactgttcat tcctgtggcg 200

 aaaagccgga gtcggcccta gacacccacg actcgcaggg tccatggttc 250

 cggaggccgt gagacctgcc ggggctgaca ggtgccagga cccatgctgc 300

 gggagcctgt gtgctcagcc ttctagggcc aggtaaagaa gctaagtgga 350

 agagtgtttc ctcctctggc cgtaaagcag ctgtccccgc cctactccgg 400

 accgccccaa agactccatg ggatggacct gagtcagccg aatcccagcc 450

 ccttcccttg ggcctgctgt ggtgctggac atcagtgaca gacggaagca 500

 ggagaccatc aaggctacgg gaggcccggg gcgcttgcga agatgaagtt 550

 tggctgcctc tccttccggc agccttatgc tggctttgtc ttaaatggaa 600

 tcaagactgt ggagacgcgc tggcgtcccc tgctgagcag ccagcggaac 650

 tgtaccatcg ccgtccacat tgctcacagg gactgggaag gcgatgcctg 700

 gcgggagctg ctggtggaga gactcgggat gactcctgct cagattcagg 750

 ccttgctcag gaaaggggaa aagtttggtc gaggagtgat agcgggactc 800

 gttgacattg gggaaacttt gcaatgcccc gaagacttaa ctcccgatga 850

 ggttgtggaa ctagaaaatc aagctgtact gaccaacctg aagcagaagt 900

 acctgactgt gatttcaaac cccaggtggt tactggagcc catacctagg 950

 aaaggaggca aggatgtatt ccaggtagac atcccagagc acctgatccc 1000

 tttggggcat gaagtgtgac aagtgtgggc tcctgaaagg aatgttccag 1050

 agaaaccagc taaatcatga caccttcaat ttgccatcat gacgcagacc 1100

 tgtatacatt aggttaaatc tgaatttcca ctgctttgga gagtcccacc 1150

 cactaagcac tgtgcatgta aacaggttcc tttgctcaga tgaaggaagt 1200

 agggggtggg gctttccttg tgtgatgcct ccttaggcac acaggcaatg 1250

 tctcaagtac tttgacctta gggtagaagg caaagctgcc agtaaatgtc 1300

 tcagcattgc tgctaatttt ggtcctgcta gtttctggat tgtacaaata 1350

 aatgtgttgt agatgaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1400

 aaaa 1404

<210> 2773
<211> 158
<212> PRT
<213> Homo sapien

<400> 2773
 Met Lys Phe Gly Cys Leu Ser Phe Arg Gln Pro Tyr Ala Gly Phe
   1               5                  10                  15

 Val Leu Asn Gly Ile Lys Thr Val Glu Thr Arg Trp Arg Pro Leu
                  20                  25                  30

 Leu Ser Ser Gln Arg Asn Cys Thr Ile Ala Val His Ile Ala His
                  35                  40                  45

 Arg Asp Trp Glu Gly Asp Ala Trp Arg Glu Leu Leu Val Glu Arg
                  50                  55                  60

 Leu Gly Met Thr Pro Ala Gln Ile Gln Ala Leu Leu Arg Lys Gly
                  65                  70                  75

 Glu Lys Phe Gly Arg Gly Val Ile Ala Gly Leu Val Asp Ile Gly
                  80                  85                  90

 Glu Thr Leu Gln Cys Pro Glu Asp Leu Thr Pro Asp Glu Val Val
                  95                 100                 105

 Glu Leu Glu Asn Gln Ala Val Leu Thr Asn Leu Lys Gln Lys Tyr
                 110                 115                 120

 Leu Thr Val Ile Ser Asn Pro Arg Trp Leu Leu Glu Pro Ile Pro
                 125                 130                 135

 Arg Lys Gly Gly Lys Asp Val Phe Gln Val Asp Ile Pro Glu His
                 140                 145                 150

 Leu Ile Pro Leu Gly His Glu Val
                 155

<210> 2774
<211> 1528
<212> DNA
<213> Homo sapien

<400> 2774
 aggcttttaa acgagaggta gagtgaccta gcactaagca aatgagctga 50

 aatgtcggaa acagagtcca tcagcttatt tggccacacg atcccaaact 100

 agttttatct tgggaaatgg ccctgtcctc agcattccct tcttgtgctg 150

 gtggggccag tgaagtcttg atcttatcag aaaaaggcca caccaagtgc 200

 gagttttccc aggctgactt tccaggccct tatcaaatga aacaacagaa 250

 gctcttcaca gttctgtgcc ccatggccac tccacagaca gacaatacca 300

 agcatcttag aactgtcata agataggtca tgcctgaaat agatcttgac 350

 catatgagag tcccagaaat cagcaaggcc tggacaaata gaactaagag 400

 agaggcagag gcaggaagct gcgggtctat cttgtaaaga gtttagcatc 450

 actgtgagag tgtgtgtcta aaattaaatt aaactagaag cagcaggtga 500

 gtatttggta agtacttctg tgactcgcct caattcccac tggccagggg 550

 ccatctcaac tgcacggtga atcaagatgc tggtgtcatc ctccttggaa 600

 aaaggaaatg ttaactcatg gttaaaacta agtacaatga ttcccaaggg 650

 atcactttct tattttttta aatgacatta aggagaatct taagaaagca 700

 tcagagaaag acatgtgcat gtgaagcacc ctgattctga tgttaggaaa 750

 acttaagcga acaggacctg ctgcacacag ccccattgtc ttctatccat 800

 ttctctttat cattcaaatc aagcaacatg tgccctcctc atcaacacac 850

 attcttcccc tttgtcagta tgcatctccc agcttagtgt caggatactt 900

 tcgattcata attatgtatg atccaaagtg tgcataattt catttaacgt 950

 taaagaaata gatccaattc ctttcttgca accaaaaata aataaaatac 1000

 gttgcctcaa tataaggttt gggctattct gtgtttctat agaagcaatc 1050

 tgtttttggt aaaatgtact tttaaggatc cagtcatctg aagtatttta 1100

 tgtagagtta gagatttcac aatattgact atacatatat ttaaaatata 1150

 aattatccag ctgatgtttg aatttgtctt actttcctgg ccacctcgtt 1200

 gtcctatttt ataagctggg gagttaacta gcttaacaaa agatgcttag 1250

 cttttgtaaa agaacaagtg tttcatttta caaagacact ccaaatgata 1300

 gttacttgat tttctcgaga cctttaacta tggtgatgaa taacaggact 1350

 tgctttcaag ccttaataaa tgtaaaatgc cttttaatga agatacagct 1400

 gagtgttttc ctcatgaatc tgaaccaatt accaatttgt gttccagtct 1450

 tgattggtat tgactgattc aaataaagtt ggtttatttt caaatattaa 1500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1528

<210> 2775
<211> 69
<212> PRT
<213> Homo sapien

<400> 2775
 Met Ala Leu Ser Ser Ala Phe Pro Ser Cys Ala Gly Gly Ala Ser
   1               5                  10                  15

 Glu Val Leu Ile Leu Ser Glu Lys Gly His Thr Lys Cys Glu Phe
                  20                  25                  30

 Ser Gln Ala Asp Phe Pro Gly Pro Tyr Gln Met Lys Gln Gln Lys
                  35                  40                  45

 Leu Phe Thr Val Leu Cys Pro Met Ala Thr Pro Gln Thr Asp Asn
                  50                  55                  60

 Thr Lys His Leu Arg Thr Val Ile Arg
                  65

<210> 2776
<211> 2529
<212> DNA
<213> Homo sapien

<400> 2776
 gaagcgattg cgagccagcg cgcgcgcttc ggcgttcccg gcggtctgcg 50

 aagtttccgg agccccggtc ccgccgcggg ttcgcgcttg tgctcgcgct 100

 cgttcctgga gtcggcggcc gctgcgcgcg ctcgttgccc aacccggtcc 150

 ccgcccccag acacgccggg ctctcggggc accacagcca tgtgctcgtt 200

 agcgtcaggc gctaccggtt attcacatct gctgaagaaa cattttcaca 250

 ctgtaagtct gagcatcagt ttaatattga cagcatggtt cataaacatg 300

 gacttgaatt ttatggatac attaagctaa taaattttat tagacttaag 350

 aatcctacag ttgagtacat gaattccata tacaacccag tgccttggga 400

 gaaagaagag tatttgaagc cagtattaga agatgacctt ttacttcaat 450

 ttgatgtaga agatctttat gaaccggtgt cagtaccctt ctcatacccc 500

 aatggactca gtgaaaatac atctgttgtt gaaaaattga aacatatgga 550

 agccagggca ctgtctgctg aagccgcatt ggccagagca cgtgaggatc 600

 tgcaaaaaat gaaacaattt gctcaggatt ttgtgatgca cacagatgtc 650

 agaacctgct cgtcatctac tagtgtcatt gcggacctcc aggaggatga 700

 ggatggtgtt tatttcagct catacgggca ttatgggata catgaagaaa 750

 tgctaaagga caaaatacga acagaaagct accgagattt catataccaa 800

 aatccacata tcttcaaaga caaggtagtt ttggatgttg ggtgtggaac 850

 tggaattctc tctatgtttg ctgctaaagc tggggcgaag aaggttcttg 900

 gagttgatca atctgaaata ctttaccagg caatggatat tataagacta 950

 aataaacttg aagatactat tacactaatt aaaggaaaga ttgaagaagt 1000

 tcatcttcct gtagaaaaag tagatgttat catatctgag tggatgggct 1050

 attttcttct gtttgagtct atgttagatt ctgtccttta tgcaaagaac 1100

 aaatacttgg caaaaggagg ctcggtctac cctgacattt gcactatcag 1150

 ccttgtagca gtgagtgatg tgaataaaca tgctgataga attgcttttt 1200

 gggatgatgt ctatggcttc aagatgtcct gcatgaagaa agcagttatt 1250

 ccagaagctg ttgtggaagt tttagatccg aagactctta tttcagaacc 1300

 ttgtggtatt aagcatatag attgccatac gacgtctatc tcagatttgg 1350

 aattttcatc agattttacc ctgaaaatca caaggacatc catgtgcacg 1400

 gcaattgctg gctactttga tatatatttt gagaagaatt gccacaacag 1450

 ggtcgtgttc tctacgggcc ctcagagcac caaaacacac tggaaacaaa 1500

 cagtatttct actggaaaaa ccattttcag ttaaagcagg tgaagccttg 1550

 aaaggaaagg tcacagttca caagaataag aaagatccac gttctctcac 1600

 cgtgaccctc acgttgaata attcaactca aacttatggt ctccagtgaa 1650

 acagccataa aagcacacta ccttgtagtt tttaatgtgg gggtagagtg 1700

 ggtcagcagg agggagctgg ttttatgtga gcagatggat ggatgatgga 1750

 ccctttccta atgagcctcc tcaataagag agaagttctc attgtgggaa 1800

 tctgacatag ttcagctgag gaagagaatc agctgatcct catggtctgc 1850

 cacgtaatca ttttcttaga cgtttgctcc accagattta accaaatgta 1900

 actcccacat tgagtttatc tatattgaaa atcatttaca ttggcctata 1950

 tttggaagag agatagtctt ttgtttttaa taagtttctt actataaatt 2000

 ttaaacaaat tggttagtta tttggatatt ttattaaact agtaacacag 2050

 gtactacaca ttttattatg gactcctctg aggaggagtt tttaattgta 2100

 tttgctagaa aatcaggatg taataaagat ttgtataaaa aaactaaaat 2150

 atggaaaaga gcttcagcct tcatatacaa atcatatatg cagacagcct 2200

 agttgattat ctagcatact tagggttctc attttgtagt ttcttccctc 2250

 tttgtgacta ttccttagcc ttatagattt ctagtactgc ccaggaaatc 2300

 taatttcaat acatttatcc taggtttcat gaaagttttt aaagattggg 2350

 ataaatatgt acttatttac taacgtatta tctttttcaa accagattta 2400

 tgtgcaaagg ttaaacatgt aactgttact aagcagtcta taaagttgtc 2450

 atttacaatt actgattcaa tttgaaatgt agaataaaat tttaataaaa 2500

 tgtatcctta taaaaaaaaa aaaaaaaaa 2529

<210> 2777
<211> 548
<212> PRT
<213> Homo sapien

<400> 2777
 Ser Asp Cys Glu Pro Ala Arg Ala Leu Arg Arg Ser Arg Arg Ser
   1               5                  10                  15

 Ala Lys Phe Pro Glu Pro Arg Ser Arg Arg Gly Phe Ala Leu Val
                  20                  25                  30

 Leu Ala Leu Val Pro Gly Val Gly Gly Arg Cys Ala Arg Ser Leu
                  35                  40                  45

 Pro Asn Pro Val Pro Ala Pro Arg His Ala Gly Leu Ser Gly His
                  50                  55                  60

 His Ser His Val Leu Val Ser Val Arg Arg Tyr Arg Leu Phe Thr
                  65                  70                  75

 Ser Ala Glu Glu Thr Phe Ser His Cys Lys Ser Glu His Gln Phe
                  80                  85                  90

 Asn Ile Asp Ser Met Val His Lys His Gly Leu Glu Phe Tyr Gly
                  95                 100                 105

 Tyr Ile Lys Leu Ile Asn Phe Ile Arg Leu Lys Asn Pro Thr Val
                 110                 115                 120

 Glu Tyr Met Asn Ser Ile Tyr Asn Pro Val Pro Trp Glu Lys Glu
                 125                 130                 135

 Glu Tyr Leu Lys Pro Val Leu Glu Asp Asp Leu Leu Leu Gln Phe
                 140                 145                 150

 Asp Val Glu Asp Leu Tyr Glu Pro Val Ser Val Pro Phe Ser Tyr
                 155                 160                 165

 Pro Asn Gly Leu Ser Glu Asn Thr Ser Val Val Glu Lys Leu Lys
                 170                 175                 180

 His Met Glu Ala Arg Ala Leu Ser Ala Glu Ala Ala Leu Ala Arg
                 185                 190                 195

 Ala Arg Glu Asp Leu Gln Lys Met Lys Gln Phe Ala Gln Asp Phe
                 200                 205                 210

 Val Met His Thr Asp Val Arg Thr Cys Ser Ser Ser Thr Ser Val
                 215                 220                 225

 Ile Ala Asp Leu Gln Glu Asp Glu Asp Gly Val Tyr Phe Ser Ser
                 230                 235                 240

 Tyr Gly His Tyr Gly Ile His Glu Glu Met Leu Lys Asp Lys Ile
                 245                 250                 255

 Arg Thr Glu Ser Tyr Arg Asp Phe Ile Tyr Gln Asn Pro His Ile
                 260                 265                 270

 Phe Lys Asp Lys Val Val Leu Asp Val Gly Cys Gly Thr Gly Ile
                 275                 280                 285

 Leu Ser Met Phe Ala Ala Lys Ala Gly Ala Lys Lys Val Leu Gly
                 290                 295                 300

 Val Asp Gln Ser Glu Ile Leu Tyr Gln Ala Met Asp Ile Ile Arg
                 305                 310                 315

 Leu Asn Lys Leu Glu Asp Thr Ile Thr Leu Ile Lys Gly Lys Ile
                 320                 325                 330

 Glu Glu Val His Leu Pro Val Glu Lys Val Asp Val Ile Ile Ser
                 335                 340                 345

 Glu Trp Met Gly Tyr Phe Leu Leu Phe Glu Ser Met Leu Asp Ser
                 350                 355                 360

 Val Leu Tyr Ala Lys Asn Lys Tyr Leu Ala Lys Gly Gly Ser Val
                 365                 370                 375

 Tyr Pro Asp Ile Cys Thr Ile Ser Leu Val Ala Val Ser Asp Val
                 380                 385                 390

 Asn Lys His Ala Asp Arg Ile Ala Phe Trp Asp Asp Val Tyr Gly
                 395                 400                 405

 Phe Lys Met Ser Cys Met Lys Lys Ala Val Ile Pro Glu Ala Val
                 410                 415                 420

 Val Glu Val Leu Asp Pro Lys Thr Leu Ile Ser Glu Pro Cys Gly
                 425                 430                 435

 Ile Lys His Ile Asp Cys His Thr Thr Ser Ile Ser Asp Leu Glu
                 440                 445                 450

 Phe Ser Ser Asp Phe Thr Leu Lys Ile Thr Arg Thr Ser Met Cys
                 455                 460                 465

 Thr Ala Ile Ala Gly Tyr Phe Asp Ile Tyr Phe Glu Lys Asn Cys
                 470                 475                 480

 His Asn Arg Val Val Phe Ser Thr Gly Pro Gln Ser Thr Lys Thr
                 485                 490                 495

 His Trp Lys Gln Thr Val Phe Leu Leu Glu Lys Pro Phe Ser Val
                 500                 505                 510

 Lys Ala Gly Glu Ala Leu Lys Gly Lys Val Thr Val His Lys Asn
                 515                 520                 525

 Lys Lys Asp Pro Arg Ser Leu Thr Val Thr Leu Thr Leu Asn Asn
                 530                 535                 540

 Ser Thr Gln Thr Tyr Gly Leu Gln
                 545

<210> 2778
<211> 4348
<212> DNA
<213> Homo sapien

<400> 2778
 gggctcgggg tccgcccgcg ggctgccggt gcgagcgggc ggcccggctc 50

 ccctcctccc ccgcccgccg ccgccgctgt gattgggtgg aagatggcgc 100

 tggccggatg gaaatcctaa tgacagtctc caaattcgcc tccatctgta 150

 ccatgggcgc caatgcttcg gcattagaga aagagattgg tccagaacag 200

 tttccggtca atgagcacta ttttggatta gtcaattttg ggaatacctg 250

 ctactgcaat tcagttcttc aagcacttta tttttgtcgt ccatttcggg 300

 aaaaagttct tgcgtataag agtcaaccta ggaaaaagga gagccttctt 350

 acatgcttag cagatctctt ccatagcata gccactcaga agaaaaaggt 400

 tggagtaata ccccctaaga agttcatcac aagattacgg aaagaaaatg 450

 agctttttga caactacatg caacaagatg cccatgaatt cttaaattac 500

 ctactaaata caattgctga tattttacaa gaagagagaa agcaggaaaa 550

 acaaaatggt cgtttaccta atggtaatat tgataatgaa aataataaca 600

 gcacaccaga cccaacgtgg gttcatgaga tttttcaggg aacattaact 650

 aatgaaacca gatgtcttac ttgtgaaact ataagcagca aagatgaaga 700

 ttttttagac ctttctgttg acgtggaaca aaatacatca attactcact 750

 gcttaagggg tttcagcaac acagaaactc tgtgcagtga atacaagtat 800

 tactgtgaag agtgtcgcag caaacaggaa gcacacaaac ggatgaaagt 850

 taaaaaactg cccatgattc tagctctaca cctgaagaga tttaaatata 900

 tggatcaact tcatcgatat acaaaactct cttaccgggt agtttttcct 950

 ttagaacttc gtctgtttaa cacttcaggt gatgccacca atccagacag 1000

 aatgtacgac cttgttgctg ttgtggttca ctgtggaagt ggtcccaatc 1050

 gaggccatta tattgcaata gttaagagtc atgatttttg gttgttgttt 1100

 gatgacgaca ttgtagaaaa aatagatgca caagctattg aagaattcta 1150

 cgggttgaca tcagatatct caaagaactc tgagtctggt tacatccttt 1200

 tctatcagtc tcgggactga gagggaaccg tgatgaagag acactttctg 1250

 cctcatttct tctctggtta ttttggaaag gatcaagcac tgatttttca 1300

 agaaaagaga aatgcaggaa gctcaggggg cagtagcaca ctttgcacac 1350

 gataaagcaa agacgatgga ttgacaagcc cttccgatca tggtagttga 1400

 tttatttgct caggtatcat gctgtctgta cagttccata caacaaggag 1450

 gtgaaatcag agataccagc tcctctttta aaacagcctt ccagtcattg 1500

 gcacgcattt tctctttatt aattgcacca ataatgcttt gaattccttg 1550

 ggggtgcagt agaaagaatc ggaatctgtg ccgtattgat aaggagatga 1600

 tgttgaacac actgcataaa tttgcctggt tcagtatgta tagaaggcat 1650

 attcagtggt cttttcaaga gtaaaccaga aatacttttg ggcccaacac 1700

 ttgcagttgc cttcctgatg taaaaactaa catgctagat aatccagtgt 1750

 cgggaagaca aagatgtttt gcttctctga agaagcttat aataatatac 1800

 agtatatgta tatgtaggga gcaattggtc aaaagtggct ttttgtttcc 1850

 ccaagggaaa gactggcttt gtaattataa ttttttcctt atttatttta 1900

 cttaaaactg gtagagtcta agtattatat gaagtgccca tgattctgtc 1950

 agtaaatttg aacatatttt tattagttaa tgtcagttta agttgtcctt 2000

 ttgtttgttt ctatttttaa ggtgaatttt aatttctatc tgaaatcagt 2050

 taagatacct tgagaaaaac tgcagtgaga ggagataaat atcctttttc 2100

 aggaggaact gatatctctg gctaaatatt tgtcctttta ttatggtttc 2150

 taaatcagtt attttcttca gctttaattt cataaaatta aaaaactatt 2200

 ttaaaaattc ctgtagttgt tggaataatt aaaaattctg gtgcagtggt 2250

 ggtataccaa tctttagaat tcttaagtat tctaatgttt caagttgaga 2300

 tcatgcttgg gaaaatcatg tcatagcatt tatgttattt tcagatgcca 2350

 ttttttaccc tggaaagaag tcataatgtt catcataacc ctagcagcct 2400

 ggatagtgag ctaaacaaac ccttcaaaga ttaaatttta atcaagtaga 2450

 ccgggaatac aaaagacaag tccttccttc ccttcccccc acctttacaa 2500

 atcttactgg aagggtgttc agaaattaaa atctgtgttt gctaagactt 2550

 cattctgttg ggggttttaa gaagtaatat atgtaacata aaatatatgt 2600

 aaacgattgc agtttttttg gacgtttttc catgcatcag taagttgtct 2650

 gacagtagcc aaatgtaact tgcagaaaat tattgaaaat tatattcaga 2700

 ataatagcaa tcaggccttg gatgttcttt attaaactct tttcaggcag 2750

 taaatttaaa aaaaattgtc attttctaaa gtccttttgc taaaactgtt 2800

 gactatggaa aacaacaaaa aggaattttt tagtctgctg ctattattaa 2850

 catttattat ctgtatcttt tggctcagga aatgacttca cctatttttt 2900

 ccataagcag acctttaaca gagtcactta attgggctgc ttaaacggat 2950

 gttctgggag aaaattataa tatttagtat ttgtacaaaa tatcaaaaag 3000

 tattttgaca agtttctttt taagatagtt cctaaagcct taccctggct 3050

 agaggtgttt tgtacaaatt atatataagc cagcctgatc taccaacatg 3100

 ccacagagaa tcacaatcaa cagtgtgggg aaagtcaggg cagtggaagt 3150

 ggatgcactc tttttatttt gaaggcttaa accaaattgt cttggaatta 3200

 aagctgtatt tctgcagctt tcggtacaga gaaaaagagg aaagtgaagc 3250

 tgtgtcagtt ttaacattag ctatatcaac atgtttaaga aagatagatg 3300

 aagtcatttg cataaaggta cagcattgaa atactatgtt gtgtttgttt 3350

 ttacattttt gcattaaaaa aaaacatgcc gtaaaagcca agttaaattt 3400

 catattaaag caagttctag tgtatgtgtt gagttcctgg taatcacata 3450

 cttgttcaca tctacaccgt acttcatagt atgatttgtc aggggaggga 3500

 ttgtggggtg acagttttac atttactttt tcttcttaat gcagctggat 3550

 ctaagtaaaa tgttttgaag tttatcagaa actaaatgta cttttaaaac 3600

 gtatagggtc agggttgggg gaaaaataca ggtatagtaa gtaagaaaag 3650

 tgacccatga agaaagcatc gtgaggttgt atgttggttg actgtgatta 3700

 aaatgcgggg ctggtgtaag ttgtaagtgg tggctgattg ccgtgtaact 3750

 atgtacatga ttgttgggat ggctgtccca tattttgtat attggaataa 3800

 aaatttctat aaattattgt aactaaaagt aaatattcta aattaagtcc 3850

 cacttcttaa gtcacatggc ttctgtcttg gaaattttac ctttaaaaga 3900

 ttatttaaga caggaaccag gaggcttggg aacagggaaa gagggaaatg 3950

 ttgtattatg tgggtcttgg ggcctctaac catcagtata gggttttttc 4000

 tttccttgat ggcagtagaa agacctcatt ttcataacat aactactctt 4050

 gatactttct ttaaaaacac tttttattaa agattctatc atgaggtatt 4100

 tggctgggag ctgggaggct aaagcgctca tgtcctggct cttcagtgaa 4150

 tttaactgtg tgaccttggg caagtcactt aacctctctg tgcttcagtc 4200

 tccctgtctt gtaaaatggg agtaatacct acctcacagg gttgttgtgg 4250

 ggattaatta gagataatgt ctgtaaagca tttaaggttc ttgaagaagg 4300

 cactatataa atacaaaata atatctatta aagttggttt atttgtga 4348

<210> 2779
<211> 2113
<212> DNA
<213> Homo sapien

<400> 2779
 gtgcggttgg gaacgcggag cggacggatt cgattcaacg gggttccgga 50

 ccgcgctgcg ctatggagca ggtcaatgag ctgaaggaga aaggcaacaa 100

 ggccctgagc gtgggtaaca tcgatgatgc cttacagtgc tactccgaag 150

 ctattaagct ggatccccac aaccacgtgc tgtacagcaa ccgttctgct 200

 gcctatgcca agaaaggaga ctaccagaag gcttatgagg atggctgcaa 250

 gactgtcgac ctaaagcctg actggggcaa gggctattca cgaaaagcag 300

 cagctctaga gttcttaaac cgctttgaag aagccaagcg aacctatgag 350

 gagggcttaa aacacgaggc aaataaccct caactgaaag agggtttaca 400

 gaatatggag gccaggttgg cagagagaaa attcatgaac cctttcaaca 450

 tgcctaatct gtatcagaag ttggagagtg atcccaggac aaggacacta 500

 ctcagtgatc ctacctaccg ggagctgata gagcagctac gaaacaagcc 550

 ttctgacctg ggcacgaaac tacaagatcc ccggatcatg accactctca 600

 gcgtcctcct tggggtcgat ctgggcagta tggatgagga ggaagagatt 650

 gcaacacctc caccaccacc ccctcccaaa aaggagacca agccagagcc 700

 aatggaagaa gatcttccag agaataagaa gcaggcactg aaagaaaaag 750

 agctggggaa cgatgcctac aagaagaaag actttgacac agccttgaag 800

 cattacgaca aagccaagga gctggacccc actaacatga cttacattac 850

 caatcaagca gcggtatact ttgaaaaggg cgactacaat aagtgccggg 900

 agctttgtga gaaggccatt gaagtgggga gagaaaaccg agaagactat 950

 cgacagattg ccaaagcata tgctcgaatt ggcaactcct acttcaaaga 1000

 agaaaagtac aaggatgcca tccatttcta taacaagtct ctggcagagc 1050

 accgaacccc agatgtgctc aagaaatgcc agcaggcaga gaaaatcctg 1100

 aaggagcaag agcggctggc ctacataaac cccgacctgg ctttggagga 1150

 gaagaacaaa ggcaacgagt gttttcagaa aggggactat ccccaggcca 1200

 tgaagcatta tacagaagcc atcaaaagga acccgaaaga tgccaaatta 1250

 tacagcaatc gagctgcctg ctacaccaaa ctcctggagt tccagctggc 1300

 actcaaggac tgtgaggaat gtatccagct ggagccgacc ttcatcaagg 1350

 gttatacacg gaaagccgct gcgctggaag cgatgaagga ctacaccaaa 1400

 gccatggatg tgtaccagaa ggcgctagac ctggactcca gctgtaagga 1450

 ggcggcagac ggctaccagc gctgtatgat ggcgcagtac aaccggcacg 1500

 acagccccga agatgtgaag cgacgagcca tggccgaccc tgaggtgcag 1550

 cagatcatga gtgacccagc catgcgcctt atcctggaac agatgcagaa 1600

 ggacccccag gcactcagcg aacacttaaa gaatcctgta atagcacaga 1650

 agatccagaa gctgatggat gtgggtctga ttgcaattcg gtgatgactt 1700

 gttcatcccc ccttcccttc gccctcatgt ggaaagagga gctgggaccg 1750

 cggcgagcag cacggagcgg aagggagagc aggggagaga aggcctcatc 1800

 tctctatatt tatacataac cccggggaag acacagagac tcgtacctgc 1850

 gctgtttgtg ccgccgctgc ctctgggccc tcccagcaca cgcatggtct 1900

 cttcaccgct gccctcgagt tccatgtctc tttcccctgc ccctagttgc 1950

 tgtctcggct gctctcccat agttggtttt ttttttattt ggggcagtgg 2000

 gcatgttatg gggaggggag ggggttcttc cagcctcagg tcccagctgt 2050

 ctcacgttgt ttattctgcg tccccttctc caataaaaca agccagttgg 2100

 gcgtggttat aac 2113

<210> 2780
<211> 543
<212> PRT
<213> Homo sapien

<400> 2780
 Met Glu Gln Val Asn Glu Leu Lys Glu Lys Gly Asn Lys Ala Leu
   1               5                  10                  15

 Ser Val Gly Asn Ile Asp Asp Ala Leu Gln Cys Tyr Ser Glu Ala
                  20                  25                  30

 Ile Lys Leu Asp Pro His Asn His Val Leu Tyr Ser Asn Arg Ser
                  35                  40                  45

 Ala Ala Tyr Ala Lys Lys Gly Asp Tyr Gln Lys Ala Tyr Glu Asp
                  50                  55                  60

 Gly Cys Lys Thr Val Asp Leu Lys Pro Asp Trp Gly Lys Gly Tyr
                  65                  70                  75

 Ser Arg Lys Ala Ala Ala Leu Glu Phe Leu Asn Arg Phe Glu Glu
                  80                  85                  90

 Ala Lys Arg Thr Tyr Glu Glu Gly Leu Lys His Glu Ala Asn Asn
                  95                 100                 105

 Pro Gln Leu Lys Glu Gly Leu Gln Asn Met Glu Ala Arg Leu Ala
                 110                 115                 120

 Glu Arg Lys Phe Met Asn Pro Phe Asn Met Pro Asn Leu Tyr Gln
                 125                 130                 135

 Lys Leu Glu Ser Asp Pro Arg Thr Arg Thr Leu Leu Ser Asp Pro
                 140                 145                 150

 Thr Tyr Arg Glu Leu Ile Glu Gln Leu Arg Asn Lys Pro Ser Asp
                 155                 160                 165

 Leu Gly Thr Lys Leu Gln Asp Pro Arg Ile Met Thr Thr Leu Ser
                 170                 175                 180

 Val Leu Leu Gly Val Asp Leu Gly Ser Met Asp Glu Glu Glu Glu
                 185                 190                 195

 Ile Ala Thr Pro Pro Pro Pro Pro Pro Pro Lys Lys Glu Thr Lys
                 200                 205                 210

 Pro Glu Pro Met Glu Glu Asp Leu Pro Glu Asn Lys Lys Gln Ala
                 215                 220                 225

 Leu Lys Glu Lys Glu Leu Gly Asn Asp Ala Tyr Lys Lys Lys Asp
                 230                 235                 240

 Phe Asp Thr Ala Leu Lys His Tyr Asp Lys Ala Lys Glu Leu Asp
                 245                 250                 255

 Pro Thr Asn Met Thr Tyr Ile Thr Asn Gln Ala Ala Val Tyr Phe
                 260                 265                 270

 Glu Lys Gly Asp Tyr Asn Lys Cys Arg Glu Leu Cys Glu Lys Ala
                 275                 280                 285

 Ile Glu Val Gly Arg Glu Asn Arg Glu Asp Tyr Arg Gln Ile Ala
                 290                 295                 300

 Lys Ala Tyr Ala Arg Ile Gly Asn Ser Tyr Phe Lys Glu Glu Lys
                 305                 310                 315

 Tyr Lys Asp Ala Ile His Phe Tyr Asn Lys Ser Leu Ala Glu His
                 320                 325                 330

 Arg Thr Pro Asp Val Leu Lys Lys Cys Gln Gln Ala Glu Lys Ile
                 335                 340                 345

 Leu Lys Glu Gln Glu Arg Leu Ala Tyr Ile Asn Pro Asp Leu Ala
                 350                 355                 360

 Leu Glu Glu Lys Asn Lys Gly Asn Glu Cys Phe Gln Lys Gly Asp
                 365                 370                 375

 Tyr Pro Gln Ala Met Lys His Tyr Thr Glu Ala Ile Lys Arg Asn
                 380                 385                 390

 Pro Lys Asp Ala Lys Leu Tyr Ser Asn Arg Ala Ala Cys Tyr Thr
                 395                 400                 405

 Lys Leu Leu Glu Phe Gln Leu Ala Leu Lys Asp Cys Glu Glu Cys
                 410                 415                 420

 Ile Gln Leu Glu Pro Thr Phe Ile Lys Gly Tyr Thr Arg Lys Ala
                 425                 430                 435

 Ala Ala Leu Glu Ala Met Lys Asp Tyr Thr Lys Ala Met Asp Val
                 440                 445                 450

 Tyr Gln Lys Ala Leu Asp Leu Asp Ser Ser Cys Lys Glu Ala Ala
                 455                 460                 465

 Asp Gly Tyr Gln Arg Cys Met Met Ala Gln Tyr Asn Arg His Asp
                 470                 475                 480

 Ser Pro Glu Asp Val Lys Arg Arg Ala Met Ala Asp Pro Glu Val
                 485                 490                 495

 Gln Gln Ile Met Ser Asp Pro Ala Met Arg Leu Ile Leu Glu Gln
                 500                 505                 510

 Met Gln Lys Asp Pro Gln Ala Leu Ser Glu His Leu Lys Asn Pro
                 515                 520                 525

 Val Ile Ala Gln Lys Ile Gln Lys Leu Met Asp Val Gly Leu Ile
                 530                 535                 540

 Ala Ile Arg


<210> 2781
<211> 3846
<212> DNA
<213> Homo sapien

<400> 2781
 cacataaatg catttcttaa agtatttaaa aacaacacac aaaaaataag 50

 cacattctaa atctaataga actaaaaatt atgaaaagtg tttaatacat 100

 agtctttaaa atagtaatct tcttttaaat atatcttttt ttattggtta 150

 gcttttctat aggagaaaac caaaaggact aagtggtgcc ttgcaggaag 200

 taggaataga attctcagga cgagaacatt ctggttagta tacattaaaa 250

 attatgtaag ccatttgact tttaaaaaat acttcatatg aatttcattt 300

 tttggtaatg tcattagtaa gggatatctt cagcctaaaa aaaaaaaact 350

 cctaatctaa acaattcaca ttgtttctaa gactttcaaa ttaccacttt 400

 cataaactat tgtaagataa actgccatct agtggctttc tagttgctaa 450

 gaagaatgaa aagaatgagc caaatcaaat ggagattaaa caagtgctca 500

 aataatagaa tggactagtg aaaaaactga acaagactat tagattattc 550

 acaaatcctg gttcctgcag aacgctggcc acattttggg gaactgtcta 600

 atacattttc atatcctcct ctataaatgt ggacgagctt gtctttcact 650

 ggtaatgctg ccatagcctt ccacttccaa gaccagttta tcatgattaa 700

 aattagtaga tggtcataaa actaaaactg tgttccaatt tctacacaag 750

 tggtgttttt ctttttaagt tatttcttta gcactaagga aatagtacta 800

 gtaccactaa attcagtgtt tgatatctgt atcctcaggg ttggacgatt 850

 ctcggaatac tgcccttctt gcttggaaaa tgatcagaga tggttgtgta 900

 atgaaaatta caaggtcgtt gaacaaggtt agtagtgtct tgccttttta 950

 ttctgtcatc tcaaacttca taaacagtca tacgttcttt gaaacgtaga 1000

 tttaatgtgt gcagtcattt ataaatcaat gacatttctc ttttttgtca 1050

 taaaactgta tactgaagaa attaacgaat gcacagtttc taaagctgtt 1100

 gcatttgtct gtggaatcat aggttcccac taagaagaat ttcagcattc 1150

 tggccagaaa tttgaataca attcaagttg aagaaatgtc tgcctgtaac 1200

 attagcatcc agggtcccag catatataat aaggagccta aaaatataat 1250

 aaatcctcat gaaaaagttc aaatgaagtc aatttgtgca aattctccta 1300

 taaaggcaca acaggatcaa ttacaagtaa aaaacaatat aaaagcaagt 1350

 cttcacaatg tcaaaagttc cttacctctt tttaatacta agtcctctac 1400

 ttctgtgggg cagttgcagt ctcctacctt gaattcacct atctgtatgc 1450

 aaaagcaagg aaaaaatgaa catcttgcat ttaataccaa atctaaggct 1500

 tcaacagttg gttcagaatt ggtacttgtt tctaccaccg ttccaactgt 1550

 tcatcatgtt tctgatttgg aaatgagctc tactctggac tgtttacctg 1600

 tgttggctga ttgggaggat gtggttttac tgccagcatc tcagcctgag 1650

 gaaaacgtag actgtacagt tcccattagt gactcagact tagagatttc 1700

 atttaattct ggagaaagat taatggtttt gaaagaattg gaaatgtcaa 1750

 gtcatgaaaa ctttggagac atagaggaaa ctcctcaaaa atctgagact 1800

 tctaagtcta ttgtgtacaa gagtcctcac actactattt ataatgtaaa 1850

 agaagccaaa gatccaggtt cagatatttc tgcctttaag ttacctgaac 1900

 acaaatcaag taccttcaac agagttaatg ccaatatgtc tcatccttta 1950

 gttttgggga aacatcctct tctttcaggt ggtaccaaaa ggaatccatg 2000

 cagtccccaa gctttcccac cagcaaaaaa acaacccttc actattcatg 2050

 aagaaaagcc tacatcatct gattgctccc cagtaagaag ttcttcctgg 2100

 aggcgtctcc catctatatt aacttctaca gttaacctac aagagccatg 2150

 gaagagtggg aaaatgacac ctccattatg caagtgtggt cggagatcta 2200

 agagacttgt tgtttctaat aatggaccga accatggaaa agtcttctat 2250

 tgttgcccta tcgggaaata ccaagaaaac agaaaatgtt gtggttattt 2300

 caaatgggaa caaacacttc aaaaggaaag agccaacagc atggttccat 2350

 ctcattccac agggggactc acttttagtt ctccagaaac aagccatatt 2400

 tgtgacagaa atttaagtat ttccaccaaa aattctttga gactcaggcc 2450

 ttcaatgagg aattgataac ctttcatgta tgaatcctaa ttgttccttg 2500

 aatttccaaa catgagtatt ctgataacat cttacactat tttattttta 2550

 ttttatatat taatgtttac tgcatttacc atactttctt caggaaccac 2600

 aagtgtaatc ttttgtaaac agtatttatt agattacata taataagcaa 2650

 caatagtata tgatccttct tttatagtta gaccttgaaa caagtctaaa 2700

 ctatttttaa attatttgca aaaaatgtga ctaataaaaa tccctagtct 2750

 attttcaggt agattcttgt actttgagat tatcataatc ttctaactga 2800

 tattttatat ttttctaaaa acttttataa gttctttagt tttatttcag 2850

 gcttgaacat tggttctgat ttgtatatca acatatcaga agaattagtc 2900

 aactaaagtt tgaaaaccta tgtagcagag atctggttca gaaactgctt 2950

 ctatactata catttaaaaa ttaatcagca attgatggta ttatttttat 3000

 attaagaaat gataggaaca ttgacactaa tgtggaggaa tttgccaaat 3050

 attttatttc aaaatttagc ctctgatatc ataaccacaa gatattttaa 3100

 atcaacagtt tctaagcata ctaccacagt ttttatgacc tctccatcat 3150

 cttgtggttt ctagagattg acagatacta tgtttgtttt atagatatgg 3200

 taattaatga aacaacttta aattgtcttc cattctttct tcctcagttc 3250

 atttcttttt gtcttcccac tgatagtctt tggcagctct tgaataaatt 3300

 ctacctgttg gcatcaaggg gaagaaaatt agcctggaaa tttttatctt 3350

 tacataaagc caattatata gcagtttgat tatgaattct aggtggaaga 3400

 attagaatag tctttggaat gggttttggg taacagccaa aatagggaaa 3450

 agggtattgt taggaaagtt gtcttgatat taagtattta ctgtgagtcc 3500

 agtaagccaa aggaccaaac aaaataggtt cagggtttca ttttaatctc 3550

 aaagattctg attcttaccc atatgtcatc agttcagttt gggacatgtg 3600

 gtgcagcatg tgtgaagaaa atattcatta aaatgtaaaa ataaacactt 3650

 gaaattgtcc acaacactga gcaaatattc gttataatta ggatgcctac 3700

 ctttctggga tatttgtaag gtgctgtagt ttttttaaca tgctcctgaa 3750

 tctcctttat tagttgttct tgatcatgtg acttgtaatc aggatttaga 3800

 acgacaaaag cctttactac ctaaaataaa tatttgaaac accagg 3846

<210> 2782
<211> 447
<212> PRT
<213> Homo sapien

<400> 2782
 Val Pro Thr Lys Lys Asn Phe Ser Ile Leu Ala Arg Asn Leu Asn
   1               5                  10                  15

 Thr Ile Gln Val Glu Glu Met Ser Ala Cys Asn Ile Ser Ile Gln
                  20                  25                  30

 Gly Pro Ser Ile Tyr Asn Lys Glu Pro Lys Asn Ile Ile Asn Pro
                  35                  40                  45

 His Glu Lys Val Gln Met Lys Ser Ile Cys Ala Asn Ser Pro Ile
                  50                  55                  60

 Lys Ala Gln Gln Asp Gln Leu Gln Val Lys Asn Asn Ile Lys Ala
                  65                  70                  75

 Ser Leu His Asn Val Lys Ser Ser Leu Pro Leu Phe Asn Thr Lys
                  80                  85                  90

 Ser Ser Thr Ser Val Gly Gln Leu Gln Ser Pro Thr Leu Asn Ser
                  95                 100                 105

 Pro Ile Cys Met Gln Lys Gln Gly Lys Asn Glu His Leu Ala Phe
                 110                 115                 120

 Asn Thr Lys Ser Lys Ala Ser Thr Val Gly Ser Glu Leu Val Leu
                 125                 130                 135

 Val Ser Thr Thr Val Pro Thr Val His His Val Ser Asp Leu Glu
                 140                 145                 150

 Met Ser Ser Thr Leu Asp Cys Leu Pro Val Leu Ala Asp Trp Glu
                 155                 160                 165

 Asp Val Val Leu Leu Pro Ala Ser Gln Pro Glu Glu Asn Val Asp
                 170                 175                 180

 Cys Thr Val Pro Ile Ser Asp Ser Asp Leu Glu Ile Ser Phe Asn
                 185                 190                 195

 Ser Gly Glu Arg Leu Met Val Leu Lys Glu Leu Glu Met Ser Ser
                 200                 205                 210

 His Glu Asn Phe Gly Asp Ile Glu Glu Thr Pro Gln Lys Ser Glu
                 215                 220                 225

 Thr Ser Lys Ser Ile Val Tyr Lys Ser Pro His Thr Thr Ile Tyr
                 230                 235                 240

 Asn Val Lys Glu Ala Lys Asp Pro Gly Ser Asp Ile Ser Ala Phe
                 245                 250                 255

 Lys Leu Pro Glu His Lys Ser Ser Thr Phe Asn Arg Val Asn Ala
                 260                 265                 270

 Asn Met Ser His Pro Leu Val Leu Gly Lys His Pro Leu Leu Ser
                 275                 280                 285

 Gly Gly Thr Lys Arg Asn Pro Cys Ser Pro Gln Ala Phe Pro Pro
                 290                 295                 300

 Ala Lys Lys Gln Pro Phe Thr Ile His Glu Glu Lys Pro Thr Ser
                 305                 310                 315

 Ser Asp Cys Ser Pro Val Arg Ser Ser Ser Trp Arg Arg Leu Pro
                 320                 325                 330

 Ser Ile Leu Thr Ser Thr Val Asn Leu Gln Glu Pro Trp Lys Ser
                 335                 340                 345

 Gly Lys Met Thr Pro Pro Leu Cys Lys Cys Gly Arg Arg Ser Lys
                 350                 355                 360

 Arg Leu Val Val Ser Asn Asn Gly Pro Asn His Gly Lys Val Phe
                 365                 370                 375

 Tyr Cys Cys Pro Ile Gly Lys Tyr Gln Glu Asn Arg Lys Cys Cys
                 380                 385                 390

 Gly Tyr Phe Lys Trp Glu Gln Thr Leu Gln Lys Glu Arg Ala Asn
                 395                 400                 405

 Ser Met Val Pro Ser His Ser Thr Gly Gly Leu Thr Phe Ser Ser
                 410                 415                 420

 Pro Glu Thr Ser His Ile Cys Asp Arg Asn Leu Ser Ile Ser Thr
                 425                 430                 435

 Lys Asn Ser Leu Arg Leu Arg Pro Ser Met Arg Asn
                 440                 445

<210> 2783
<211> 534
<212> DNA
<213> Homo sapien

<400> 2783
 ctttccctgc cgccgccgag tcgcgcggag gcggaggctt gggtgcgttc 50

 aagattcagc ttcacccgta acccaccgcc atggccgagg aaggcattgc 100

 tgctggaggt gtaatggacg ttaatactgc tttacaagag gttctgaaga 150

 ctgccctcat ccacgatggc ctagcacgtg gaattcgcga agctgccaaa 200

 gccttagaca agcgccaagc ccatctttgt gtgcttgcat ccaactgtga 250

 tgagcctatg tatgtcaagt tggtggaggc cctttgtgct gaacaccaaa 300

 tcaacctaat taaggttgat gacaacaaga aactaggaga atgggtaggc 350

 ctttgtaaaa ttgacagaga ggggaaaccc cgtaaagtgg ttggttgcag 400

 ttgtgtagta gttaaggact atggcaagga gtctcaggcc aaggatgtca 450

 ttgaagagta tttcaaatgc aagaaatgaa gaaataaatc tttggctcac 500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 534

<210> 2784
<211> 132
<212> PRT
<213> Homo sapien

<400> 2784
 Met Ala Glu Glu Gly Ile Ala Ala Gly Gly Val Met Asp Val Asn
   1               5                  10                  15

 Thr Ala Leu Gln Glu Val Leu Lys Thr Ala Leu Ile His Asp Gly
                  20                  25                  30

 Leu Ala Arg Gly Ile Arg Glu Ala Ala Lys Ala Leu Asp Lys Arg
                  35                  40                  45

 Gln Ala His Leu Cys Val Leu Ala Ser Asn Cys Asp Glu Pro Met
                  50                  55                  60

 Tyr Val Lys Leu Val Glu Ala Leu Cys Ala Glu His Gln Ile Asn
                  65                  70                  75

 Leu Ile Lys Val Asp Asp Asn Lys Lys Leu Gly Glu Trp Val Gly
                  80                  85                  90

 Leu Cys Lys Ile Asp Arg Glu Gly Lys Pro Arg Lys Val Val Gly
                  95                 100                 105

 Cys Ser Cys Val Val Val Lys Asp Tyr Gly Lys Glu Ser Gln Ala
                 110                 115                 120

 Lys Asp Val Ile Glu Glu Tyr Phe Lys Cys Lys Lys
                 125                 130

<210> 2785
<211> 3576
<212> DNA
<213> Homo sapien

<400> 2785
 tttaacagta ggtattgaga tttttattta aacagtaggt attgagattt 50

 ttatttttct accttataag acatacaata agacatacaa tattgttgct 100

 cagattcagg gtgatggtaa catttagctc agaatattcc cattctgatt 150

 aatttactga atttaggagt gcaagtaatt tttagataat aaactatggg 200

 tatcacatct ggctttcaat tagctgtaaa atacttattg tgatcaatat 250

 ccagttgtta cagtttggaa ggcaaagtac cactaccaga aaaatgctga 300

 cacctttcag ctgaacctta aatgccaata atactgtatc tttatcatag 350

 tgggtttgcc agccatcttg tttggtcagg catagtgcct gacttaagag 400

 gaaactgtgg gcactttgat ggtgagaaac gtcctctttc caaccttctt 450

 cttaggcttt gtggcatgtg catgacacaa actgggttga ccttaaaata 500

 atactcaatg gctaatccta atgagttata aggaaataga aagggatggc 550

 tttttatgca caacctaaac acattttaat tatattttgc tcatttttgg 600

 agaacccatt cccttttaca tctattatga acattctaaa acttaaattt 650

 gtgaaaacaa aactctggga gatagattgt aattttattc catgaggaag 700

 gtgttaaacc agctttgcag tttgaatttt attcttaaag gctctgcagt 750

 tcttacctgg atgtcgaaat gatttttaat ttcaactgct gtagacctca 800

 tcctgtggga actagaaata atgtccaact gccgtccagt ctggcgacat 850

 tccagccgtt cccccacccc acgataacgg cctgactctt cctcaattca 900

 tgacagccca ttctacacat aacctttctc ctctggcacc ggtcctccca 950

 gcagagaggg atcctgccct tcccttccca ctctccagca tacagaccag 1000

 caggaagcca caagagggaa aaacaaaagc cttctgtata aggcctatga 1050

 aaggaccatg ggccagcctc agaatctgct gcccctacaa accagtattc 1100

 ctcaaatgat agttccacat ttacttaata aggaggacta attttctaat 1150

 tttaaaaatt gtgttcctgc cagattcaca taagtaattc atttccaccg 1200

 gcgaaggcaa tgtcaacaat ttaaaacgaa aaatcagtaa attacccttc 1250

 caaaaatacc tttctgctgt tctgattccc aatctttttc ttgcaatttc 1300

 ctgaaccaga gatgttatcg ggacttacat acataatcaa tacataaaat 1350

 caatcctcaa gtctccataa tgtctctgtt ctatatgttt gttttgcagg 1400

 gttactatga atgaaaaaga caatttcatg aatgcagaaa atctggggat 1450

 cgtgtttggg cccactctga tgaggccccc tgaggacagc accctgacca 1500

 ccctgcatga tatgcggtac caaaagctga ttgtgcagat tttaatagaa 1550

 aacgaagacg ttttattcta atccatcagg gaaatgagct gaatggcccc 1600

 agcaccatcc aagttgacac agctaaagga ataaaaacat ttcttaccac 1650

 ttgatttgtt ttccaagcaa gtgctagaat ttgctggact gcagaggatc 1700

 gctgagtggg gtactgtgtc tcatagacat gcgccacctc cacgtgagaa 1750

 caagggtgaa ggtgagggaa gcccctcacc ttgggtcttt tgctgtgcct 1800

 cctatgtatg tctggtttgc tggaagagtg attaatacat ctttaattta 1850

 ttaaaaaaca atgtagacct ttaaacttca gtcttattgg taataaaagg 1900

 gaacttaatt catacaggta cttgatacag ttatacattt tccacttaca 1950

 aaaagaagac aattctgtta aatgaaacct gtatcgtaaa atgtattttt 2000

 attttaccca cgagaatgtt gttattttta gcaaatagaa ctcaatgcag 2050

 tgcattggtt attaccctgt gtaccttgtc cctcattttg ctgtgacacc 2100

 ctgaaaaagc tgaccacaaa tgcagtatta tcttgacata cctctgtcct 2150

 cctcagtgct ttttaatgaa atttcacctg ccccttgtgt tcctgctttg 2200

 gatagttttt gctcttaagc attggcattc ttctattgta tggtatgtat 2250

 ttatagcaat tgtaggatgg tctgaaatgt ccacacactt tctatgcata 2300

 caaattttgt gaattcccaa agtatgcttt ggaattggtc atagtctttt 2350

 cgtatcatga gtgtgtatcc cagaagatac agaatgcggt cattttacct 2400

 gaaattattt gagaacactg gatgtatctg gtctgtgtaa aaagttagca 2450

 cttttaccct cttttcttcc tggccaagcc ctctgaattc atctgttaat 2500

 atcaaattgt atttttgcca catttctgta ttggtgaaaa gcgaatctgc 2550

 agaataactg ccaacgtttt tcattcttgt tttacaaacc tattttttaa 2600

 agtgagaata aggttggttt ttaccaaata tttgttcctc cttgacaaaa 2650

 gtagctctgt gtggataata tgattttatt actacagttc cagtcacttg 2700

 gttatattta tcttagcatg agcctttcac accaagattt ctatattttg 2750

 taacataggt gaaatattta aaacatcaaa aactgtaaat ctagattttt 2800

 aaaaaatcca actgcaatgt cttttccttt gattgagatg atttgtgtaa 2850

 actcaccagt cttgctttgg agtgagcaga agagaatgac tattttacgt 2900

 ggagcatcat tgtgtgactg ttgacctgga cagtcccaag ggctatgcag 2950

 atggactcca ttggcacagg gaggtttgac ctcttccctg ctattatccc 3000

 tcctcccaac tgtacagatt tgtttgttgt agtttatgta cttcttgata 3050

 ctgtcaaaaa attatctgga aatggtttta ttttgtgaag tgaacaatac 3100

 tttgtaattt atgatagtgt aaatggaagg caaagcatca catgtattaa 3150

 attcttctgt ctattattct ggagtatgtg caagaaagtg gtttggaggg 3200

 atggggtggt ggatcatcaa aacattgttt ccagatagac gctggcaaca 3250

 aattttcagt catcactgaa acacaatgag aaaacagcat ctcatcgagt 3300

 ccccactcct tctgcaagct cccttctaga gagcctgctt caagattaag 3350

 gccctgaggc tccacattca ctttccataa gccccactgc atggatgcat 3400

 catcatacag aggtgaaccg tttagggcaa atcaccctag gccacttgga 3450

 gggtagcaga acaagacttt taaagtcaga aagccctgag tttgatccca 3500

 gatccgtcca tttagtacta cctgcatata accatgggaa gtttgcggct 3550

 ctgaaaaact gaagttgatt atctga 3576

<210> 2786
<211> 9
<212> PRT
<213> Homo sapien

<400> 2786
 Leu Thr Val Gly Ile Glu Ile Phe Ile
   1               5

<210> 2787
<211> 6249
<212> DNA
<213> Homo sapien

<400> 2787
 ggtgcggaga aagaggtcac taaaatgttc cccaggggcc ttcggcgagt 50

 cttttgtttg gtttttgttt ttaatctgtg gctcttgata atttatctag 100

 tggttgccta cacctgaaaa acaagacaca gtgtttaact atcaacgaaa 150

 gaactggacg gctccccgcc gcagtcccac tccccgagtt tgtggctggc 200

 atttgggcca cgccgggctg ggcggtcaca gcgaggggcg cgcagtttgg 250

 ggtcacacag ctccgcttct aggccccaac caccgttaaa aggggaagcc 300

 cgtgccccat caggtccgct cttgctgagc ccagagccat cccgcgctct 350

 gcgggctggg aggcccgggc caggacgcga gtcctgcgca gccgaggttc 400

 cccagcgccc cctgcagccg cgcgtaggca gagacggagc ccggccctgc 450

 gcctccgcac cacgcccggg accccaccca gcggcccgta cccggagaag 500

 cagcgcgagc acccgaagct cccggctggc ggcagaaacc gggagtgggg 550

 ccgggcgagt gcgcggcatc ccaggccggc ccgaacgctc cgcccgcggt 600

 tgggccgact tcccctcctc ttccctctct ccttccttta gcccgctggc 650

 gccggacacg ctgcgcctca tctcttgggg cgttcttccc cgttggccaa 700

 ccgtcgcatc ccgtgcaact ttggggtagt ggccgtttag tgttgaatgt 750

 tccccaccga gagcgcatgg cttgggaagc gaggcgcgaa cccggccccc 800

 gaagggccgc cgtccgggag acggtgatgc tgttgctgtg cctgggggtc 850

 ccgaccggcc gcccctacaa cgtggacact gagagcgcgc tgctttacca 900

 gggcccccac aacacgctgt tcggctactc ggtcgtgctg cacagccacg 950

 gggcgaaccg atggctccta gtgggtgcgc ccactgccaa ctggctcgcc 1000

 aacgcttcag tgatcaatcc cggggcgatt tacagatgca ggatcggaaa 1050

 gaatcccggc cagacgtgcg aacagctcca gctgggtagc cctaatggag 1100

 aaccttgtgg aaagacttgt ttggaagaga gagacaatca gtggttgggg 1150

 gtcacacttt ccagacagcc aggagaaaat ggatccatcg tgacttgtgg 1200

 gcatagatgg aaaaatatat tttacataaa gaatgaaaat aagctcccca 1250

 ctggtggttg ctatggagtg ccccctgatt tacgaacaga actgagtaaa 1300

 agaatagctc cgtgttatca agattatgtg aaaaaatttg gagaaaattt 1350

 tgcatcatgt caagctggaa tatccagttt ttacacaaag gatttaattg 1400

 tgatgggggc cccaggatca tcttactgga ctggctctct ttttgtctac 1450

 aatataacta caaataaata caaggctttt ttagacaaac aaaatcaagt 1500

 aaaatttgga agttatttag gatattcagt cggagctggt cattttcgga 1550

 gccagcatac taccgaagta gtcggaggag ctcctcaaca tgagcagatt 1600

 ggtaaggcat atatattcag cattgatgaa aaagaactaa atatcttaca 1650

 tgaaatgaaa ggtaaaaagc ttggatcgta ctttggagct tctgtctgtg 1700

 ctgtggacct caatgcagat ggcttctcag atctgctcgt gggagcaccc 1750

 atgcagagca ccatcagaga ggaaggaaga gtgtttgtgt acatcaactc 1800

 tggctcggga gcagtaatga atgcaatgga aacaaacctc gttggaagtg 1850

 acaaatatgc tgcaagattt ggggaatcta tagttaatct tggcgacatt 1900

 gacaatgatg gctttgaaga tgttgctatc ggagctccac aagaagatga 1950

 cttgcaaggt gctatttata tttacaatgg ccgtgcagat gggatctcgt 2000

 caaccttctc acagagaatt gaaggacttc agatcagcaa atcgttaagt 2050

 atgtttggac agtctatatc aggacaaatt gatgcagata ataatggcta 2100

 tgtagatgta gcagttggtg cttttcggtc tgattctgct gtcttgctaa 2150

 ggacaagacc tgtagtaatt gttgacgctt ctttaagcca ccctgagtca 2200

 gtaaatagaa cgaaatttga ctgtgttgaa aatggatggc cttctgtgtg 2250

 catagatcta acactttgtt tctcatataa gggcaaggaa gttccaggtt 2300

 acattgtttt gttttataac atgagtttgg atgtgaacag aaaggcagag 2350

 tctccaccaa gattctattt ctcttctaat ggaacttctg acgtgattac 2400

 aggaagcata caggtgtcca gcagagaagc taactgtaga acacatcaag 2450

 catttatgcg gaaagatgtg cgggacatcc tcaccccaat tcagattgaa 2500

 gctgcttacc accttggtcc tcatgtcatc agtaaacgaa gtacagagga 2550

 attcccacca cttcagccaa ttcttcagca gaagaaagaa aaagacataa 2600

 tgaaaaaaac gataaacttt gcaaggtttt gtgcccatga aaattgttct 2650

 gctgatttac aggtttctgc aaagattggg tttttgaagc cccatgaaaa 2700

 taaaacatat cttgctgttg ggagtatgaa gacattgatg ttgaatgtgt 2750

 ccttgtttaa tgctggagat gatgcatatg aaacgactct acatgtcaaa 2800

 ctacccgtgg gtctttattt cattaagatt ttagagctgg aagagaagca 2850

 aataaactgt gaagtcacag ataactctgg cgtggtacaa cttgactgca 2900

 gtattggcta tatatatgta gatcatctct caaggataga tattagcttt 2950

 ctcctggatg tgagctcact cagcagagcg gaagaggacc tcagtatcac 3000

 agtgcatgct acctgtgaaa atgaagagga aatggacaat ctaaagcaca 3050

 gcagagtgac tgtagcaata cctttaaaat atgaggttaa gctgactgtt 3100

 catgggtttg taaacccaac ttcatttgtg tatggatcaa atgatgaaaa 3150

 tgagcctgaa acgtgcatgg tggagaaaat gaacttaact ttccatgtta 3200

 tcaacactgg caatagtatg gctcccaatg ttagtgtgga aataatggta 3250

 ccaaattctt ttagccccca aactgataag ctgttcaaca ttttggatgt 3300

 ccagactact actggagaat gccactttga aaattatcaa agagtgtgtg 3350

 cattagagca gcaaaagagt gcaatgcaga ccttgaaagg catagtccgg 3400

 ttcttgtcca agactgataa gaggctattg tactgcataa aagctgatcc 3450

 acattgttta aatttcttgt gtaattttgg gaaaatggaa agtggaaaag 3500

 aagccagtgt tcatatccaa ctggaaggcc ggccatccat tttagaaatg 3550

 gatgagactt cagcactcaa gtttgaaata agagcaacag gttttccaga 3600

 gccaaatcca agagtaattg aactaaacaa ggatgagaat gttgcgcatg 3650

 ttctactgga aggactacat catcaaagac ccaaacgtta tttcaccata 3700

 gtgattattt caagtagctt gctacttgga cttattgtac ttctgttgat 3750

 ctcatatgtt atgtggaagg ctggcttctt taaaagacaa tacaaatcta 3800

 tcctacaaga agaaaacaga agagacagtt ggagttatat caacagtaaa 3850

 agcaatgatg attaaggact tctttcaaat tgagagaatg gaaaacagac 3900

 tcaggttgta gtaaagaaat ttaaaagaca ctgtttacaa gaaaaaatga 3950

 attttgtttg gacttctttt actcatgatc ttgtgacata ttatgtcttc 4000

 atgcaagggg aaaatctcag caatgattac tctttgagat agaagaactg 4050

 caaaggtaat aatacagcca aagataatct ctcagctttt aaatgggtag 4100

 agaaacacta aagcattcaa tttattcaag aaaagtaagc ccttgaagat 4150

 atcttgaaat gaaagtataa ctgagttaaa ttatactgga gaagtcttag 4200

 acttgaaata ctacttacca tatgtgcttg cctcagtaaa atgaacccca 4250

 ctgggtgggc agaggttcat ttcaaataca tctttgatac ttgttcaaaa 4300

 tatgttcttt aaaaatataa ttttttagag agctgttccc aaattttcta 4350

 acgagtggac cattatcact ttaaagccct ttatttataa tacatttcct 4400

 acgggctgtg ttccaacaac catttttttt cagcagacta tgaatattat 4450

 agtattatag gccaaactgg caaacttcag actgaacatg tacactggtt 4500

 tgagcttagt gaaatgactt ctggataatt atttttttat aattatggat 4550

 ttcaccatct ttctttctgt atatatacat gtgtttttat gtaggtatat 4600

 atttaccatt cttcctatct attcttccta taacacacct ttatcaagca 4650

 tacccaggag taatcttcaa atcttttgtt atattctgaa acaaaagatt 4700

 gtgagtgttg cactttacct gatacacgct gatttagaaa atacagaaac 4750

 catacctcac taataacttt aaaatcaaag ctgtgcaaag actagggggc 4800

 ctatacttca tatgtattat gtactatgta aaatattgac tatcacacaa 4850

 ctatttcctt ggatgtaatt ctttgttacc ctttacaagt ataagtgttt 4900

 acaagtataa gtgttacctt acatggaaac gaagaaacaa aattcataaa 4950

 tttaaattca taaatttagc tgaaagatac tgattcaatt tgtatacagt 5000

 gaatataaat gagacgacag caaaattttc atgaaatgta aaatattttt 5050

 atagtttgtt catactatat gaggttctat tttaaatgac tttctggatt 5100

 ttaaaaaatt tctttaaata caatcatttt tgtaatattt attttatgct 5150

 tatgatctag ataattgcag aatatcattt tatctgactc tgtcttcata 5200

 agagagctgt ggccgaattt tgaacatctg ttatagggag tgatcaaatt 5250

 agaaggcaat gtggaaaaac aattctggga aagatttctt tatatgaagt 5300

 ccctgccact agccagccat cctaattgat gaaagttatc tgttcacagg 5350

 cctgcagtga tggtgaggaa tgttctgaaa tttgcgaagg catttgagta 5400

 gtgaaatgta agcacaaaac ctcctgaacc cagagtgtgt atacacagga 5450

 ataaacttta tgacatttat gtatttttaa aaaactttgt atcgttataa 5500

 aaaggctagt cattctttca ggagaacatc taggatcata gatgaaaaat 5550

 caagccccga tttagaactg tcttctccag gatggtctct aaggaaattt 5600

 acatttggtt ctttcctact cagaactact cagaaacaac tatatatttc 5650

 aggttatttg agcacagtga aagcagagta ctatggttgt ccaacacagg 5700

 cctctcagat acaaggggaa cacaattaca tattgggcta gattttgccc 5750

 agttcaaaat agtatttgtt atcaacttac tttgttactt gtatcatgaa 5800

 ttttaaaacc ctaccacttt aagaagacag ggatgggtta ttcttttttg 5850

 gcaggtaggc tatataacta tgtgattttg aaatttaact gctctggatt 5900

 agggagcagt gaatcaaggc agacttatga aatctgtatt atatttgtaa 5950

 cagaatatag gaaatttaac ataattgatg agctcaaatc ctgaaaaatg 6000

 aaagaatcca aattatttca gaattatcta ggttaaatat tgatgtatta 6050

 tgatggttgc aaagtttttt tgtgtgtcca ataaacacat tgtaaaaaaa 6100

 agaatttgaa ttgatatcta aaaacagaat ttgaattgat atttcatctt 6150

 gacttttaaa gccctagagg ctaattgtta gtaacatcaa tttctattag 6200

 gatatccgtt tggccacaca gcaggaggtt agagcaatgg agcattact 6249

<210> 2788
<211> 1032
<212> PRT
<213> Homo sapien

<400> 2788
 Met Ala Trp Glu Ala Arg Arg Glu Pro Gly Pro Arg Arg Ala Ala
   1               5                  10                  15

 Val Arg Glu Thr Val Met Leu Leu Leu Cys Leu Gly Val Pro Thr
                  20                  25                  30

 Gly Arg Pro Tyr Asn Val Asp Thr Glu Ser Ala Leu Leu Tyr Gln
                  35                  40                  45

 Gly Pro His Asn Thr Leu Phe Gly Tyr Ser Val Val Leu His Ser
                  50                  55                  60

 His Gly Ala Asn Arg Trp Leu Leu Val Gly Ala Pro Thr Ala Asn
                  65                  70                  75

 Trp Leu Ala Asn Ala Ser Val Ile Asn Pro Gly Ala Ile Tyr Arg
                  80                  85                  90

 Cys Arg Ile Gly Lys Asn Pro Gly Gln Thr Cys Glu Gln Leu Gln
                  95                 100                 105

 Leu Gly Ser Pro Asn Gly Glu Pro Cys Gly Lys Thr Cys Leu Glu
                 110                 115                 120

 Glu Arg Asp Asn Gln Trp Leu Gly Val Thr Leu Ser Arg Gln Pro
                 125                 130                 135

 Gly Glu Asn Gly Ser Ile Val Thr Cys Gly His Arg Trp Lys Asn
                 140                 145                 150

 Ile Phe Tyr Ile Lys Asn Glu Asn Lys Leu Pro Thr Gly Gly Cys
                 155                 160                 165

 Tyr Gly Val Pro Pro Asp Leu Arg Thr Glu Leu Ser Lys Arg Ile
                 170                 175                 180

 Ala Pro Cys Tyr Gln Asp Tyr Val Lys Lys Phe Gly Glu Asn Phe
                 185                 190                 195

 Ala Ser Cys Gln Ala Gly Ile Ser Ser Phe Tyr Thr Lys Asp Leu
                 200                 205                 210

 Ile Val Met Gly Ala Pro Gly Ser Ser Tyr Trp Thr Gly Ser Leu
                 215                 220                 225

 Phe Val Tyr Asn Ile Thr Thr Asn Lys Tyr Lys Ala Phe Leu Asp
                 230                 235                 240

 Lys Gln Asn Gln Val Lys Phe Gly Ser Tyr Leu Gly Tyr Ser Val
                 245                 250                 255

 Gly Ala Gly His Phe Arg Ser Gln His Thr Thr Glu Val Val Gly
                 260                 265                 270

 Gly Ala Pro Gln His Glu Gln Ile Gly Lys Ala Tyr Ile Phe Ser
                 275                 280                 285

 Ile Asp Glu Lys Glu Leu Asn Ile Leu His Glu Met Lys Gly Lys
                 290                 295                 300

 Lys Leu Gly Ser Tyr Phe Gly Ala Ser Val Cys Ala Val Asp Leu
                 305                 310                 315

 Asn Ala Asp Gly Phe Ser Asp Leu Leu Val Gly Ala Pro Met Gln
                 320                 325                 330

 Ser Thr Ile Arg Glu Glu Gly Arg Val Phe Val Tyr Ile Asn Ser
                 335                 340                 345

 Gly Ser Gly Ala Val Met Asn Ala Met Glu Thr Asn Leu Val Gly
                 350                 355                 360

 Ser Asp Lys Tyr Ala Ala Arg Phe Gly Glu Ser Ile Val Asn Leu
                 365                 370                 375

 Gly Asp Ile Asp Asn Asp Gly Phe Glu Asp Val Ala Ile Gly Ala
                 380                 385                 390

 Pro Gln Glu Asp Asp Leu Gln Gly Ala Ile Tyr Ile Tyr Asn Gly
                 395                 400                 405

 Arg Ala Asp Gly Ile Ser Ser Thr Phe Ser Gln Arg Ile Glu Gly
                 410                 415                 420

 Leu Gln Ile Ser Lys Ser Leu Ser Met Phe Gly Gln Ser Ile Ser
                 425                 430                 435

 Gly Gln Ile Asp Ala Asp Asn Asn Gly Tyr Val Asp Val Ala Val
                 440                 445                 450

 Gly Ala Phe Arg Ser Asp Ser Ala Val Leu Leu Arg Thr Arg Pro
                 455                 460                 465

 Val Val Ile Val Asp Ala Ser Leu Ser His Pro Glu Ser Val Asn
                 470                 475                 480

 Arg Thr Lys Phe Asp Cys Val Glu Asn Gly Trp Pro Ser Val Cys
                 485                 490                 495

 Ile Asp Leu Thr Leu Cys Phe Ser Tyr Lys Gly Lys Glu Val Pro
                 500                 505                 510

 Gly Tyr Ile Val Leu Phe Tyr Asn Met Ser Leu Asp Val Asn Arg
                 515                 520                 525

 Lys Ala Glu Ser Pro Pro Arg Phe Tyr Phe Ser Ser Asn Gly Thr
                 530                 535                 540

 Ser Asp Val Ile Thr Gly Ser Ile Gln Val Ser Ser Arg Glu Ala
                 545                 550                 555

 Asn Cys Arg Thr His Gln Ala Phe Met Arg Lys Asp Val Arg Asp
                 560                 565                 570

 Ile Leu Thr Pro Ile Gln Ile Glu Ala Ala Tyr His Leu Gly Pro
                 575                 580                 585

 His Val Ile Ser Lys Arg Ser Thr Glu Glu Phe Pro Pro Leu Gln
                 590                 595                 600

 Pro Ile Leu Gln Gln Lys Lys Glu Lys Asp Ile Met Lys Lys Thr
                 605                 610                 615

 Ile Asn Phe Ala Arg Phe Cys Ala His Glu Asn Cys Ser Ala Asp
                 620                 625                 630

 Leu Gln Val Ser Ala Lys Ile Gly Phe Leu Lys Pro His Glu Asn
                 635                 640                 645

 Lys Thr Tyr Leu Ala Val Gly Ser Met Lys Thr Leu Met Leu Asn
                 650                 655                 660

 Val Ser Leu Phe Asn Ala Gly Asp Asp Ala Tyr Glu Thr Thr Leu
                 665                 670                 675

 His Val Lys Leu Pro Val Gly Leu Tyr Phe Ile Lys Ile Leu Glu
                 680                 685                 690

 Leu Glu Glu Lys Gln Ile Asn Cys Glu Val Thr Asp Asn Ser Gly
                 695                 700                 705

 Val Val Gln Leu Asp Cys Ser Ile Gly Tyr Ile Tyr Val Asp His
                 710                 715                 720

 Leu Ser Arg Ile Asp Ile Ser Phe Leu Leu Asp Val Ser Ser Leu
                 725                 730                 735

 Ser Arg Ala Glu Glu Asp Leu Ser Ile Thr Val His Ala Thr Cys
                 740                 745                 750

 Glu Asn Glu Glu Glu Met Asp Asn Leu Lys His Ser Arg Val Thr
                 755                 760                 765

 Val Ala Ile Pro Leu Lys Tyr Glu Val Lys Leu Thr Val His Gly
                 770                 775                 780

 Phe Val Asn Pro Thr Ser Phe Val Tyr Gly Ser Asn Asp Glu Asn
                 785                 790                 795

 Glu Pro Glu Thr Cys Met Val Glu Lys Met Asn Leu Thr Phe His
                 800                 805                 810

 Val Ile Asn Thr Gly Asn Ser Met Ala Pro Asn Val Ser Val Glu
                 815                 820                 825

 Ile Met Val Pro Asn Ser Phe Ser Pro Gln Thr Asp Lys Leu Phe
                 830                 835                 840

 Asn Ile Leu Asp Val Gln Thr Thr Thr Gly Glu Cys His Phe Glu
                 845                 850                 855

 Asn Tyr Gln Arg Val Cys Ala Leu Glu Gln Gln Lys Ser Ala Met
                 860                 865                 870

 Gln Thr Leu Lys Gly Ile Val Arg Phe Leu Ser Lys Thr Asp Lys
                 875                 880                 885

 Arg Leu Leu Tyr Cys Ile Lys Ala Asp Pro His Cys Leu Asn Phe
                 890                 895                 900

 Leu Cys Asn Phe Gly Lys Met Glu Ser Gly Lys Glu Ala Ser Val
                 905                 910                 915

 His Ile Gln Leu Glu Gly Arg Pro Ser Ile Leu Glu Met Asp Glu
                 920                 925                 930

 Thr Ser Ala Leu Lys Phe Glu Ile Arg Ala Thr Gly Phe Pro Glu
                 935                 940                 945

 Pro Asn Pro Arg Val Ile Glu Leu Asn Lys Asp Glu Asn Val Ala
                 950                 955                 960

 His Val Leu Leu Glu Gly Leu His His Gln Arg Pro Lys Arg Tyr
                 965                 970                 975

 Phe Thr Ile Val Ile Ile Ser Ser Ser Leu Leu Leu Gly Leu Ile
                 980                 985                 990

 Val Leu Leu Leu Ile Ser Tyr Val Met Trp Lys Ala Gly Phe Phe
                 995                1000                1005

 Lys Arg Gln Tyr Lys Ser Ile Leu Gln Glu Glu Asn Arg Arg Asp
                1010                1015                1020

 Ser Trp Ser Tyr Ile Asn Ser Lys Ser Asn Asp Asp
                1025                1030

<210> 2789
<211> 5954
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3543-3566, 5007-5030
<223> Unknown base

<400> 2789
 cggccgccgg ccgccgagcg cgggagggca ggcaggggca ggagccggag 50

 ggcccggggc gcggcgcggc atgtagctgc gggctcccgc gtcgcgtgag 100

 gctgtcggcc cggggccccg ccatggctgg gatggacagt ggcaacctga 150

 agaccgcgag gctgtggcgg gacgccgccc tgcgtgccag gaagctgcgg 200

 agcaacctgc gccagctcac gcttaccgcc gccggggcct gccccggggc 250

 cggggccgac gcgctcgagt cccccgcctc cccccagctc gtgctgccgg 300

 ccaacctcgg ggacattgag gcactgaacc tggggaacaa cggcctggag 350

 gaggtacccg aggggctggg gtcggcgctg ggcagcctgc gcgtcctggt 400

 cctgcgcagg aaccgcttcg cccggctgcc cccggcggtg gccgagctcg 450

 gccaccacct caccgagctg gacgtgagcc acaaccggct gaccgccctg 500

 ggcgcggagg tggtgagtgc tctgagggag ctgcggaagc tcaacctcag 550

 ccacaaccag ctgcccgccc tgcccgccca gctgggcgct ctcgctcacc 600

 tggaggagct ggatgtcagc tttaaccggc tggcgcacct gcctgactcc 650

 ctctcctgcc tctcccgcct gcgcaccctg gacgtggatc acaaccagct 700

 cactgccttc ccccggcagc tgctgcagct ggtggccctg gaggagctgg 750

 acgtgtccag caaccggctg cggggcctgc ctgaggatat cagtgccctg 800

 cgtgccctca agatcctctg gctgagtggg gccgagcttg gcacgctgcc 850

 cgccggcttc tgcgagctgg ccagtttgga gagcctcatg ctagacaaca 900

 acgggctgca ggctctgccc gcccagttca gctgcctgca gcggctcaaa 950

 atgctcaacc tgtcctccaa cctcttcgag gagttccctg ccgcgctgct 1000

 gcccttggct ggtctggagg agctctacct tagtcgcaac cagctcacct 1050

 cggtgccatc cgcttatctc gggcctgggc cggctttctc accttgtggc 1100

 tggataataa ccgcatccgc tacctgccgg actccatcgt ggagctgacc 1150

 ggcctggagg agctcgtgct gcaggggaac cagatcgcgg tgctgcccga 1200

 ccactttggc cagctctccc gggtgggttt gtggaagatc aaagacaacc 1250

 cactgatcca gcccccctac gaggtctgca tgaaggggat cccctacatc 1300

 gcagcctacc agaaggaact ggctcattcc cagccggcgg tgcagccccg 1350

 gctcaagctg ctcctgatgg ggcataaggc tgcaggaaag actttgctgc 1400

 gccactgcct caccgaggag agagtggagg gatgcccagg aggaggggac 1450

 aaggagaagt gctacccacc gtcacctccc cctgtgagca agggcatcga 1500

 ggtgaccagc tggacggccg atgcctcccg gggcctgcgg ttcatcgtgt 1550

 atgacttagc tggggatgaa agttatgagg tgatccagcc cttcttcctg 1600

 tccccagggg ccctatacgt gctggtggtc aacttggcca cctatgagcc 1650

 tcgccacttt cctaccaccg tgggctcctt cttgcatcgg gtcggggcga 1700

 gagtgcccca cgcggtggtg tgcatcgtgg gcacccacgc agacctgtgc 1750

 ggagagcgtg agctggagga gaaatgtctg gacattcacc gccagatcgc 1800

 cctgcaggag aagcacgacg cggagggact gagccgcttg gccaaggtgg 1850

 tggacgaggc actggcccgg gacttcgagc tgcgctctgc cagcccccac 1900

 gcagcctact atggcgtttc ggacaagaac cttcgacggc gcaaggccca 1950

 ttttcaatac ctgctcaacc accggctgca gatcctctcc cccgtgttgc 2000

 ctgttagctg cagggacccg cgccacttac gacgccttcg ggacaagttg 2050

 ctgtcagttg ctgagcaccg agagatcttc cccaacttac acagagtact 2100

 gcctcgatcc tggcaggtgc tggaggaact gcatttccag ccacctcagg 2150

 cccagcgact gtggctaagc tggtgggact cggcgcgctt gggcctgcag 2200

 gcgggtctga ccgaggaccg actgcagagt gccctctcct acctgcatga 2250

 gagcggcaag ctactctact ttgaggacag tccggctctc aaggagcacg 2300

 tcttccacaa cctcacccgc ctcatcgaca tcctcaatgt cttcttccag 2350

 agggatccct ctttgctgct gcataagctg ctcctaggga ccagtggaga 2400

 gggcaaggcg gagggggaaa gctccccgcc catggcgcgg tccaccccca 2450

 gccaggaact gctccgggcc acccagctcc atcagtatgt ggagggcttt 2500

 ctgttgcatg ggctcttgcc agctcatgtc attcggttgc tgcttaagcc 2550

 tcatgtccag gcccagcagg acttgcagct gttgctggag ctgctggaga 2600

 agatgggact ctgttactgc ctcaataaac ccaagggcaa gcctttgaat 2650

 gggtccacag cttggtacaa gttcccatgc tatgtgcaga acgaggtgcc 2700

 ccatgcagaa gcctggatta atgggaccaa cctagctggg cagtcttttg 2750

 tggctgagca gttgcagatt gaatatagct ttccttttac ttttccacct 2800

 gggttgtttg cacgctacag tgtccagatc aacagccatg tggtgcacag 2850

 gtcggatggt aaatttcaga tctttgccta tagagggaaa gttcctgtgg 2900

 ttgtgagtta cagacctgcc aggggagtcc tgcagccaga caccctgtcc 2950

 attgctagcc atgcatcatt accaaatata tggaccgcat ggcaagccat 3000

 aacccccttg gtggaggaac tgaatgtcct acttcaggaa tggcctggac 3050

 tgcactacac cgtgcacatt ctctgttcta agtgccttaa gagaggatcg 3100

 cccaatccac atgcttttcc aggggagttg ctgagtcagc ccagaccgga 3150

 aggagtggca gagatcattt gccccaagaa cggcagcgag cgagtaaatg 3200

 ttgccttggt ttacccaccc acgccaactg tgatcagccc ctgttccaag 3250

 aagaatgttg gtgaaaagca cagaaaccag tgacgtttgt ggctgtggaa 3300

 tttccatgga gaaaagagag catctgaaca cctggaccat cttttgcacc 3350

 tggcagaccc tctgcactca ccccagcgtg ttctgtgaac ttgagtgaca 3400

 acgcgtgctt gcagggtgct ttttggatga ctggggaaga ggtggggagg 3450

 gggtggtggg gggaagcatg gacgagaaca tggagcaaat gttttacaac 3500

 ctgaacctca gaactgtgat cctccaagga gcgcgctact tgnnnnnnnn 3550

 nnnnnnnnnn nnnnnngtcg aatggcttct cagggatttt gttttccgtg 3600

 cacatataag ccatagttac agtacaggtg gcagtattta gagcactcag 3650

 atttcagttc tgttaaatgt gaaagaggga tcgactgacg ttcattgctg 3700

 ttccataact agtgtaaaat atgtatatgt ttatctttat ttttataata 3750

 tgcaaataca tttaaattta tacagtttga agcttctagc gttagttcac 3800

 actgggtgca atattctgca tgagaactgt gccaagatgg ggctgatttc 3850

 ttattttagt ataagacttt tttgtttttt ctttattctt taatcctctt 3900

 cacattaaaa aaaaaaaatc tctctgttag cccatggatt aagtgttggt 3950

 tcatagagat tgccaataat cagaaagaac cttaaatgtg catttaagac 4000

 agtgtccctt cccttctttt caatgaaggt ccctgcctat ataaatcatc 4050

 tggcacgctg gtgggaaatc ctttgctctt ccaacgtgtt attagtgctg 4100

 ggcagagatg gggcacactc aggggccaaa gaggacaaaa agtccatgca 4150

 aaacttgagt cttttaatgg cttaagataa tcaggagtca gttctgaatc 4200

 ttacaaagtg ctctgcttaa taagtacctt acttagcaga gcactttgca 4250

 aacatattac ttattagcag agctctttgt agaccttcca catctggctg 4300

 tcagatctta aggttgtgaa tttaggctcc agttacattc actggagagc 4350

 ataatcccac acgggttatt tataaataca gagcctctga ttggacggtc 4400

 tcctgccaag aactagtaat acccttgttt taaaatcttc acaaggtaaa 4450

 acttaaaaag ccaaccaaac aaattgctct ccattctact tttaattggg 4500

 ccaaacagca tatgctacag tagtaacatg tttttcggag agtgtaaaaa 4550

 actctgttta catttgcctc ctccgtgggt tgatcgaaaa tgtataaaac 4600

 tgactgcttc tcgccagcct cagacaagaa gagtgagttg ctggtactcg 4650

 ctactctttt acttcttttg taaagtattg actcttggaa ggctacagta 4700

 tacaaagtct caacatgttt tttaaaagaa ataaggagca agcgactgcc 4750

 ctgctagaaa tcacaaaccg atttttgtag aatattttgt gccccaggca 4800

 ttaatttcac tgactccaga acctgcagtt cagagaatga tttcttatga 4850

 tgataaaaat cgaatgggat cagacgatgt ttgcattttt ttaatacttg 4900

 aataggacac ctcaagtttg agatttcatt ttcttttaga acacagtcac 4950

 aagattaatc tggtgaatcc ttttgtcaca gttctcgtgt gtgtgtgcgc 5000

 gtctccnnnn nnnnnnnnnn nnnnnnnnnn aaaactgaat ggtcacattt 5050

 aattgctttt tggaccattg aatagttggg aagtaagaat tttttaattg 5100

 gcatgagacg gttcctcaac tgttaaatta accaactttg acctgtcttt 5150

 agaaaaaggc ttatttgtat gattttgggc taactccccg gggaccatat 5200

 taaatgacaa aaatgctcct ttgggtgaca caccctacaa agtatttgct 5250

 gttacgaaca taaacgccca cattcttaat atctaatatt tttgaccagt 5300

 gatgttttat gctgtcatct gaaccctaga gaagcagtgt cagaggaaac 5350

 cttggtgtca catgtgtctt agcaaaaggg ttaccatgat cgagggtcat 5400

 gtgaccaaaa gatgctccag agaagcttga gaatttgttt caagttggga 5450

 ggagggttgg agatacaaaa atcactctgc tctacaggac tcttcagctg 5500

 tctatgcaag aaattccgtt ttctctttca gcacctggaa agacacagca 5550

 gcccaccgag gcgataggtg attcactaag cacaagagga atgttttcta 5600

 agcaaggcgt cccttgcctc tcaaacaaat gccctccaag tttgttaggg 5650

 tttctattcc tgcaacttgt agtatcaaaa ccacttcctg gaattgtcaa 5700

 agcactgcca aaataaatgt ttttccccct tctaagaaaa aaaaaatgac 5750

 agtgctcata tttgacactt gtgtattgga ctctcttttg aatgaataaa 5800

 aaggaaaagg ggtttggtgt aattcctgat ggggtgcgtg ttgtttttca 5850

 tgccatggtt tgtgaatttt aattgtggtt tcccatttcg ttgttgtaac 5900

 tgggcagaaa ttaaaaaaga aaaatcaata aaaatacaaa gaaatggtta 5950

 aaaa 5954

<210> 2790
<211> 381
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3543-3566, 5007-5030
<223> Unknown amino acid

<400> 2790
 Ala Ala Gly Arg Arg Ala Arg Glu Gly Arg Gln Gly Gln Glu Pro
   1               5                  10                  15

 Glu Gly Pro Gly Arg Gly Ala Ala Cys Ser Cys Gly Leu Pro Arg
                  20                  25                  30

 Arg Val Arg Leu Ser Ala Arg Gly Pro Ala Met Ala Gly Met Asp
                  35                  40                  45

 Ser Gly Asn Leu Lys Thr Ala Arg Leu Trp Arg Asp Ala Ala Leu
                  50                  55                  60

 Arg Ala Arg Lys Leu Arg Ser Asn Leu Arg Gln Leu Thr Leu Thr
                  65                  70                  75

 Ala Ala Gly Ala Cys Pro Gly Ala Gly Ala Asp Ala Leu Glu Ser
                  80                  85                  90

 Pro Ala Ser Pro Gln Leu Val Leu Pro Ala Asn Leu Gly Asp Ile
                  95                 100                 105

 Glu Ala Leu Asn Leu Gly Asn Asn Gly Leu Glu Glu Val Pro Glu
                 110                 115                 120

 Gly Leu Gly Ser Ala Leu Gly Ser Leu Arg Val Leu Val Leu Arg
                 125                 130                 135

 Arg Asn Arg Phe Ala Arg Leu Pro Pro Ala Val Ala Glu Leu Gly
                 140                 145                 150

 His His Leu Thr Glu Leu Asp Val Ser His Asn Arg Leu Thr Ala
                 155                 160                 165

 Leu Gly Ala Glu Val Val Ser Ala Leu Arg Glu Leu Arg Lys Leu
                 170                 175                 180

 Asn Leu Ser His Asn Gln Leu Pro Ala Leu Pro Ala Gln Leu Gly
                 185                 190                 195

 Ala Leu Ala His Leu Glu Glu Leu Asp Val Ser Phe Asn Arg Leu
                 200                 205                 210

 Ala His Leu Pro Asp Ser Leu Ser Cys Leu Ser Arg Leu Arg Thr
                 215                 220                 225

 Leu Asp Val Asp His Asn Gln Leu Thr Ala Phe Pro Arg Gln Leu
                 230                 235                 240

 Leu Gln Leu Val Ala Leu Glu Glu Leu Asp Val Ser Ser Asn Arg
                 245                 250                 255

 Leu Arg Gly Leu Pro Glu Asp Ile Ser Ala Leu Arg Ala Leu Lys
                 260                 265                 270

 Ile Leu Trp Leu Ser Gly Ala Glu Leu Gly Thr Leu Pro Ala Gly
                 275                 280                 285

 Phe Cys Glu Leu Ala Ser Leu Glu Ser Leu Met Leu Asp Asn Asn
                 290                 295                 300

 Gly Leu Gln Ala Leu Pro Ala Gln Phe Ser Cys Leu Gln Arg Leu
                 305                 310                 315

 Lys Met Leu Asn Leu Ser Ser Asn Leu Phe Glu Glu Phe Pro Ala
                 320                 325                 330

 Ala Leu Leu Pro Leu Ala Gly Leu Glu Glu Leu Tyr Leu Ser Arg
                 335                 340                 345

 Asn Gln Leu Thr Ser Val Pro Ser Ala Tyr Leu Gly Pro Gly Pro
                 350                 355                 360

 Ala Phe Ser Pro Cys Gly Trp Ile Ile Thr Ala Ser Ala Thr Cys
                 365                 370                 375

 Arg Thr Pro Ser Trp Ser
                 380

<210> 2791
<211> 4480
<212> DNA
<213> Homo sapien

<400> 2791
 tcggcctccc aatgtagtgg gatttcaggc atgaccacct ggcctagttc 50

 ctatactttt cttaattctt cagacttctc acatttagta tagtgcattc 100

 atttcatctt gctgtttatt agcacccttt gtggccaagg gaaataaaag 150

 gtggtaaaat tcagttttca gtttagttct tgaaagctct gggaaatgga 200

 ggaaacacaa aactatgaat taaactaggg ctgttgattt ctgaaccccc 250

 agataaatca gttgacccac attttcattt taggtgttag gtccaaatta 300

 gcataatgtc ttgcattatt attaggttca gtgtgaaact ttacagtgct 350

 gcatttgaag tttagtaact ggttattatt aatcatttgg gaaaaatgaa 400

 aatgtgttgg gactttctat gactaggcat ttgttgatta tttttcatga 450

 ttgctttttg ttttctcatt gtgtaggatt tgtgaacttg tatattacag 500

 gaaacaagat actttgtaaa atttactggg gaaaatccat ttggagtgca 550

 tgacatttgc caggataaga aagcagtaat atgtttgtat tataaaatta 600

 caccctgcca gaaaactttc tttcctagta aggtaaatgt agaagggact 650

 tttacagcat agtaagttga ttaggagcca aaattttatt ccagtttttt 700

 tttgaactaa gaatgtttta aattctgtaa tgaactttta tgtttaccca 750

 ttactcatgc attctttcac aatatgttta atagcctgag gaaataggaa 800

 agctgtgaag ctactaccat tctttacttt taataagaat aataggaaag 850

 aaaagtcagg tcagtaatcc aaatccaaat atgtatactg caaatgctca 900

 agaagtcaca ttttttgata aattgtattg agtacagaag aacttatatg 950

 aatttattat ctgttaataa cttagttttg acaacagaat aacatttgga 1000

 aattgtgaga ataatcaagc tgtttttcca ttaacagtgt aaattcataa 1050

 catgtccttc aaaaggtgat attctaagct gtcttaattg tctacggttg 1100

 ataactttta aataaagtac aggactttct gaaagtgttt ggcacgttat 1150

 gctgccaaaa acaatctgtg ttttgaaata ccaattaatc agttaatttc 1200

 tgaagacttt gtataggact tgatatatga gtcagaatct gtctgtactc 1250

 attctgtaca ttgtaacttt gaacacttat gaaaaactgt atctgttggt 1300

 gtgttttgat tagttagtgt agatttgttt gcgtatttga attccgattt 1350

 tagtttagga agactaaaag tagccatttt tgtaaagttc atatgctatt 1400

 ttttaatgtc atttttgttt ttaatattta tacaatagtg atgttactag 1450

 taaaaaatgt ttatagataa cacgtagagc tattaactgt tcaaaagcct 1500

 acatgatagg catattttgt atttcgtgtt gcactcgttc tgtttcatat 1550

 tggacttttt acatcccttt tttagcaaaa aaaagagaca catttgaatt 1600

 ctctttagca taaagctgtg cattggaaac tatgtgactg tatccatacg 1650

 gttagcaaaa tactctttgc caccaaaggt aaatgaaact gtaaaatacc 1700

 tctggatatt tgtgccaatg aacttttctt agcatattag gattaaagca 1750

 aaaataatct tttcagtatg tttcatctag gacttacaat aaatgtttaa 1800

 accatgaaaa cttatatttc ataccctaat ttttctttga aaatattcaa 1850

 gatttgtagc ctagtgtgtt ctattttgtg tgattgcttg aatgttttct 1900

 gattttattg ggtaaaagtt tgcctagtaa tgatctttca gcaattcatt 1950

 gaaataatta tttgaagtaa tcttgcttca gatttaattt gtgatgtaca 2000

 ttgttgtaca agccatttta gtacaggtgt ctcatttatg tagttgaaag 2050

 gtgactgtgg aatttctttt gttttttatg tatttccatt cagtctcttt 2100

 atatagtcac atgtttcaca ggggaacttg tccactggaa cctaacatag 2150

 tacaaccttt taatatgcgt atcttaaagg aaaatattat aaaacaagat 2200

 attaatacta aagtgttaac attaatatgt tgttctcatg gaagaaaagt 2250

 agaaaatgtg ataggcttag aaattatttt ttatcagcat taagtgcttc 2300

 aatttctccc cataaagatt ctaaggaaat ttcagttcct catattatag 2350

 ttttccccat aatttaatat tactaagtat ttctctgccc agtaatgttg 2400

 atgcagtttg cataaatagc cttggaagta aggaggcagg acagaaagcc 2450

 aaatatcgaa atctctggcc ttgatttagt gacagtttat tctaatgggg 2500

 accataggtg ttattagtaa aaagatagtg tacaaggcct aagttcagtt 2550

 tacattgttc tttgaaatga gttcatcttt tgtgttgaat aattgtattc 2600

 taagtaggag atgcctgtat ttaacataat catgctttct atataatcaa 2650

 atatgtattt gttggaatac tggtagaaat aaccttccct tcctccactg 2700

 tgcagtggaa aaaaaactcc cgatttatac tgtatataaa ttaggaaatt 2750

 atgttacata tttacatttt taaaaatata aaaatgacat attattttga 2800

 agtgattgta ttatagtttc tgaagcttat gactggctat aaatataaca 2850

 acatacccat gagaaaccag accaaaattg aatatatatc atcactgtga 2900

 ccttgaactt atagtcattt gggataaaac agagtgtgcc ttgaaatgat 2950

 aaagagtgcc ctgcaatttt ataactgtac attttattat gggtggtcct 3000

 ctcaaattgg ccccaaatcc ttgtcttcga ggttggtgaa ataaaagttt 3050

 aaaataaaag ttgactggta tttcctttag tatttccaga actattgctg 3100

 tagaggcctc ccttaatttt cagagttctc attttgaatt aaagtagact 3150

 tacgctacat agatgtagaa aattaggttt ggcttaggtt tctgaaaaaa 3200

 tattctagga gaaggtggta gcattgttct gaacttacca cacttggaaa 3250

 aactaatctt caaatgtaat tttttgtctt attaatgagt aatctgtcaa 3300

 agacatgaat tctttgactt gtgctcattc tttctgaact tattgaggct 3350

 tatatatatc aaataaggtt aatttacaca ataattattt ttaataatta 3400

 ataaactcat tcatgtagta tattttaaaa cattatttcc tctcattttt 3450

 ccttctcttt tttcttccta tatattttta aggtttcaag agaaaacggg 3500

 cttcagtttt taaaaaaatg tagacttgca tttttactgt gcttatttaa 3550

 aataatggat ataatttata ttaaggtcca aattatttta ttcacaggat 3600

 aatcatggtc tctgataaaa gatgcccaca tttctgtgta ctcacagttg 3650

 ttgtatattt ttcaatttca attttgaaag taaactcaac acattgtttt 3700

 cccattttac ctccactacc tactcgccag acaaaaatat agatttctct 3750

 aaaaacacat acaaagaaaa cgtctttcct taaaacatga tcttattgac 3800

 atgaaggtag tttgagcaag ggtatgtaat aaaataaatg gctctcaacc 3850

 tgcatcaatt tttatactat agttaaaaaa tttatagagg acaacctatg 3900

 tgttatgctg agatagactc agtaatcatt tgtttgcaaa ttgattattt 3950

 ttttctcatc catccagaaa gtacagtgca taacaacaac acttaacaag 4000

 tgcagaggaa cctgtcctgt agtatataat aaaaaatgat tgtcaccttg 4050

 ctgatctttc catttaaaca tgcatgatct ccagtacttt gtacaatgta 4100

 tagtatatta aatacattta tgtgtaattt tgtgtgtatt tttatatggt 4150

 ataattaaaa ttattacatt tatgtgattg taattcacaa aaagtactac 4200

 ttactatatt ctgtagagtg tgttgtgaat gtttttacct gtgtttgagc 4250

 attatggtgt aggtttaata gatgaatatt tgccttcagt ctctgctcag 4300

 gtattaatgt gtagtaattt ttggtgcttt ctttttaatc tgtgataatc 4350

 tggtgttctg aatgttcaaa aataaatttg gttgaatacg cacatggtaa 4400

 aaagattgct taccaattga catactctct ataataccat cttggtaaaa 4450

 actctttaca aaggatttat tggccgggcg 4480

<210> 2792
<211> 30
<212> PRT
<213> Homo sapien

<400> 2792
 Ser Ala Ser Gln Cys Ser Gly Ile Ser Gly Met Thr Thr Trp Pro
   1               5                  10                  15

 Ser Ser Tyr Thr Phe Leu Asn Ser Ser Asp Phe Ser His Leu Val
                  20                  25                  30

<210> 2793
<211> 4994
<212> DNA
<213> Homo sapien

<400> 2793
 gacgcgaggc gggttcttgg actgagtgtg cggcgcggtg cgccgccttc 50

 cgaggctcct cccgcgggtg gcagcggacg gggcgcgccc ctcggccagt 100

 cctcggtcct caggcttgtg gctccgttga gcaccggccg ccgggcctct 150

 gggtccgtcg agtggagact ctctgaaaag cgtgggctcc gtggcctccg 200

 gcgcggccgc ggcgggtcgg tctcctagat catccgggaa gcccacggga 250

 ccctcaggcg ggcaggatga acgactggca caggatcttc acccaaaacg 300

 tgcttgtccc tccccaccca cagagagcgc gccagccttg gaaggaatcc 350

 acggcattcc agtgtgtcct caagtggctg gacggaccgg taattaggca 400

 gggcgtgctg gaggtactgt cagaggttga atgccatctg cgagtgtctt 450

 tctttgatgt cacctaccgg cacttctttg ggaggacgtg gaaaaccaca 500

 gtgaagccga cgaagagacc gccgtccagg atcgtcttta atgagccctt 550

 gtattttcac acatccctaa accaccctca tatcgtggct gtggtggaag 600

 tggtcgctga gggcaagaaa cgggatggga gcctccagac attgtcctgt 650

 gggtttggaa ttcttcggat cttcagcaac cagccggact ctcctatctc 700

 tgcttcccag gacaaaaggt tgcggctgta ccatggcacc cccagagccc 750

 tcctgcaccc gcttctccag gaccccgcag agcaaaacag acacatgacc 800

 ctcattgaga actgcagcct gcagtacacg ctgaagccac acccggccct 850

 ggagcctgcg ttccaccttc ttcctgagaa ccttctggtg tctggtctgc 900

 agcagatacc tggcctgctt ccagctcatg gagaatccgg cgacgctctc 950

 cgaaagcctc gcctccagaa gcccatcacg gggcacttgg atgacttatt 1000

 cttcaccctg tacccctccc tggagaagtt tgaggaagag ctgctggagc 1050

 tccacgtcca ggaccacttc caggagggat gtggcccact ggacggtggt 1100

 gccctggaga tcctggagcg gcgcctgcgt gtgggcgtgc acaatggtct 1150

 gggcttcgtg cagaggccgc aggtcgttgt actggtgcct gagatggatg 1200

 tggccttgac gcgctcagct agcttcagca ggaaagtggt ctcctcttcc 1250

 aagaccagct ccgggagcca agctctggtt ttgagaagcc gcctccgcct 1300

 cccagagatg gtcggccacc ctgcatttgc ggtcatcttc cagctggagt 1350

 acgtgttcag cagccctgca ggagtggacg gcaatgcagc ttcggtcacc 1400

 tctctgtcca acctggcatg catgcacatg gtccgctggg ctgtttggaa 1450

 ccccttgctg gaagctgatt ctggaagggt gaccctgcct ctgcagggtg 1500

 ggatccagcc caacccctcg cactgtctgg tctacaaggt accctcagcc 1550

 agcatgagct ctgaagaggt gaagcaggtg gagtcgggta cactccggtt 1600

 ccagttctcg ctgggctcag aagaacacct ggatgcaccc acggagcctg 1650

 tcagtggccc caaagtggag cggcggcctt ccaggaaacc acccacgtcc 1700

 ccttcgagcc cgccagcgcc agtacctcga gttctcgctg ccccgcagaa 1750

 ctcacctgtg ggaccagggt tgtcaatttc ccagctggcg gcctccccgc 1800

 ggtccccgac tcagcactgc ttggccaggc ctacttcaca gctaccccat 1850

 ggctctcagg cctccccggc ccaggcacag gagttcccgt tggaggccgg 1900

 tatctcccac ctggaagccg acctgagcca gacctccctg gtcctggaaa 1950

 catccattgc cgaacagtta caggagctgc cgttcacgcc tttgcatgcc 2000

 cctattgttg tgggaaccca gaccaggagc tctgcagggc agccctcgag 2050

 agcctccatg gtgctcctgc agtcctccgg ctttcccgag attctggatg 2100

 ccaataaaca gccagccgag gctgtcagcg ctacagaacc tgtgacgttt 2150

 aaccctcaga aggaagaatc agattgtcta caaagcaacg agatggtgct 2200

 acagtttctt gcctttagca gagtggccca ggactgccga ggaacatcat 2250

 ggccaaagac tgtgtatttc accttccagt tctaccgctt cccacccgca 2300

 acgacgccac gactgcagct ggtccagctg gatgaggccg gccagcccag 2350

 ctctggcgcc ctgacccaca tcctcgtgcc tgtgagcaga gatggcacct 2400

 ttgatgctgg gtctcctggc ttccagctga ggtacatggt gggccctggg 2450

 ttcctgaagc caggtgagcg gcgctgcttt gcccgctacc tggccgtgca 2500

 gaccctgcag attgacgtct gggacggaga ctccctgctg ctcatcggat 2550

 ctgctgccgt ccagatgaag catctcctcc gccaaggccg gccggctgtg 2600

 caggcctccc acgagcttga ggtcgtggca actgaatacg agcaggacaa 2650

 catggtggtg agtggagaca tgctggggtt tggccgcgtc aagcccatcg 2700

 gcgtccactc ggtggtgaag ggccggctgc acctgacttt ggccaacgtg 2750

 ggtcacccgt gtgaacagaa agtgagaggt tgtagcacat tgccaccgtc 2800

 cagatctcgg gtcatctcaa acgatggagc cagccgcttc tctggaggca 2850

 gcctcctcac gactggaagc tcaaggcgaa aacacgtggt gcaagcacag 2900

 aagctggcgg acgtggacag tgagctggct gccatgctac tgacccatgc 2950

 ccggcagggc aaggggcccc aggacgtcag ccgcgagtcg gatgccaccc 3000

 gcaggcgtaa gctggagcgg atgaggtctg tgcgcctgca ggaggccggg 3050

 ggagacttgg gccggcgtgg gacgagcgtg ttggcgcagc agagcgtccg 3100

 cacacagcac ttgcgggacc tacaggtcat cgccgcctac cgggaacgca 3150

 cgaaggccga gagcatcgcc agcctgctga gcctggccat caccacggag 3200

 cacacgctcc acgccacgct gggggtcgcc gagttctttg agtttgtgct 3250

 taagaacccc cacaacacac agcacacggt gactgtggag atcgacaacc 3300

 ccgagctcag cgtcatcgtg gacagtcagg agtggaggga cttcaagggt 3350

 gctgctggcc tgcacacacc ggtggaggag gacatgttcc acctgcgtgg 3400

 cagcctggcc ccccagctct acctgcgccc ccacgagacc gcccacgtcc 3450

 ccttcaagtt ccagagcttc tctgcagggc agctggccat ggtgcaggcc 3500

 tctcctgggt tgagcaacga gaagggcatg gacgccgtgt caccttggaa 3550

 gtccagcgca gtgcccacta aacacgccaa ggtcttgttc cgagcgagtg 3600

 gtggcaagcc catcgccgtg ctctgcctga ctgtggagct gcagccccac 3650

 gtggtggacc aggtcttccg cttctatcac ccggagctct ccttcctgaa 3700

 gaaggccatc cgcctgccgc cctggcacac atttccaggt gctccggtgg 3750

 gaatgcttgg tgaggacccc ccagtccatg ttcgctgcag cgacccgaac 3800

 gtcatctgtg agacccagaa tgtgggcccc ggggaaccac gggacatatt 3850

 tctgaaggtg gccagtggtc caagcccgga gatcaaagac ttctttgtca 3900

 tcatttactc ggatcgctgg ctggcgacac ccacacagac gtggcaggtc 3950

 tacctccact ccctgcagcg cgtggatgtc tcctgcgtcg caggccagct 4000

 gacccgcctg tcccttgtcc ttcgggggac acagacagtg aggaaagtga 4050

 gagctttcac ctctcatccc caggagctga agacagaccc caaaggtgtc 4100

 ttcgtgctgc cgcctcgtgg ggtgcaggac ctgcatgttg gcgtgaggcc 4150

 ccttagggcc ggcagccgct ttgtccatct caacctggtg gacgtggatt 4200

 gccaccagct ggtggcctcc tggctcgtgt gcctctgctg ccgccagccg 4250

 ctcatctcca aggcctttga gatcatgttg gctgcgggcg aagggaaggg 4300

 tgtcaacaag aggatcacct acaccaaccc ctacccctcc cggaggacat 4350

 tccacctgca cagcgaccac ccggagctgc tgcggttcag agaggactcc 4400

 ttccaggtcg ggggtggaga gacctacacc atcggcttgc agtttgcgcc 4450

 tagtcagaga gtgggtgagg aggagatcct gatctacatc aatgaccatg 4500

 aggacaaaaa cgaagaggca ttttgcgtga aggtcatcta ccagtgaggg 4550

 cttgagggtg acgtccttcc tgcggcaccc agctggggcc tgtctgtgcc 4600

 cctcctgccc tgcaggctgt cctccccgcc tctctgcagc ctttcacttc 4650

 agtgcccacc tggctgacct gtgcacttgg ctgaggaagc agagaccgag 4700

 cgctggtcat tttgtagtac ctgcatccag cttagctgct gctgacaccc 4750

 agcaggcctg ggttccgtga gcgcgaactc cgtggtggtg ggtctggctc 4800

 tggtgctgcc atctacgcat gtgggaccct cgttatcgct gttgctcaaa 4850

 atgtatttta tgaatcatcc taaatgagaa aattatgttt ttcttactgg 4900

 attttgtaca aacataatct attatttgct atgcaatatt ttatgctggt 4950

 attatatctg ttttttaaat tgttgaacaa aatactaaac tttt 4994

<210> 2794
<211> 1426
<212> PRT
<213> Homo sapien

<400> 2794
 Met Asn Asp Trp His Arg Ile Phe Thr Gln Asn Val Leu Val Pro
   1               5                  10                  15

 Pro His Pro Gln Arg Ala Arg Gln Pro Trp Lys Glu Ser Thr Ala
                  20                  25                  30

 Phe Gln Cys Val Leu Lys Trp Leu Asp Gly Pro Val Ile Arg Gln
                  35                  40                  45

 Gly Val Leu Glu Val Leu Ser Glu Val Glu Cys His Leu Arg Val
                  50                  55                  60

 Ser Phe Phe Asp Val Thr Tyr Arg His Phe Phe Gly Arg Thr Trp
                  65                  70                  75

 Lys Thr Thr Val Lys Pro Thr Lys Arg Pro Pro Ser Arg Ile Val
                  80                  85                  90

 Phe Asn Glu Pro Leu Tyr Phe His Thr Ser Leu Asn His Pro His
                  95                 100                 105

 Ile Val Ala Val Val Glu Val Val Ala Glu Gly Lys Lys Arg Asp
                 110                 115                 120

 Gly Ser Leu Gln Thr Leu Ser Cys Gly Phe Gly Ile Leu Arg Ile
                 125                 130                 135

 Phe Ser Asn Gln Pro Asp Ser Pro Ile Ser Ala Ser Gln Asp Lys
                 140                 145                 150

 Arg Leu Arg Leu Tyr His Gly Thr Pro Arg Ala Leu Leu His Pro
                 155                 160                 165

 Leu Leu Gln Asp Pro Ala Glu Gln Asn Arg His Met Thr Leu Ile
                 170                 175                 180

 Glu Asn Cys Ser Leu Gln Tyr Thr Leu Lys Pro His Pro Ala Leu
                 185                 190                 195

 Glu Pro Ala Phe His Leu Leu Pro Glu Asn Leu Leu Val Ser Gly
                 200                 205                 210

 Leu Gln Gln Ile Pro Gly Leu Leu Pro Ala His Gly Glu Ser Gly
                 215                 220                 225

 Asp Ala Leu Arg Lys Pro Arg Leu Gln Lys Pro Ile Thr Gly His
                 230                 235                 240

 Leu Asp Asp Leu Phe Phe Thr Leu Tyr Pro Ser Leu Glu Lys Phe
                 245                 250                 255

 Glu Glu Glu Leu Leu Glu Leu His Val Gln Asp His Phe Gln Glu
                 260                 265                 270

 Gly Cys Gly Pro Leu Asp Gly Gly Ala Leu Glu Ile Leu Glu Arg
                 275                 280                 285

 Arg Leu Arg Val Gly Val His Asn Gly Leu Gly Phe Val Gln Arg
                 290                 295                 300

 Pro Gln Val Val Val Leu Val Pro Glu Met Asp Val Ala Leu Thr
                 305                 310                 315

 Arg Ser Ala Ser Phe Ser Arg Lys Val Val Ser Ser Ser Lys Thr
                 320                 325                 330

 Ser Ser Gly Ser Gln Ala Leu Val Leu Arg Ser Arg Leu Arg Leu
                 335                 340                 345

 Pro Glu Met Val Gly His Pro Ala Phe Ala Val Ile Phe Gln Leu
                 350                 355                 360

 Glu Tyr Val Phe Ser Ser Pro Ala Gly Val Asp Gly Asn Ala Ala
                 365                 370                 375

 Ser Val Thr Ser Leu Ser Asn Leu Ala Cys Met His Met Val Arg
                 380                 385                 390

 Trp Ala Val Trp Asn Pro Leu Leu Glu Ala Asp Ser Gly Arg Val
                 395                 400                 405

 Thr Leu Pro Leu Gln Gly Gly Ile Gln Pro Asn Pro Ser His Cys
                 410                 415                 420

 Leu Val Tyr Lys Val Pro Ser Ala Ser Met Ser Ser Glu Glu Val
                 425                 430                 435

 Lys Gln Val Glu Ser Gly Thr Leu Arg Phe Gln Phe Ser Leu Gly
                 440                 445                 450

 Ser Glu Glu His Leu Asp Ala Pro Thr Glu Pro Val Ser Gly Pro
                 455                 460                 465

 Lys Val Glu Arg Arg Pro Ser Arg Lys Pro Pro Thr Ser Pro Ser
                 470                 475                 480

 Ser Pro Pro Ala Pro Val Pro Arg Val Leu Ala Ala Pro Gln Asn
                 485                 490                 495

 Ser Pro Val Gly Pro Gly Leu Ser Ile Ser Gln Leu Ala Ala Ser
                 500                 505                 510

 Pro Arg Ser Pro Thr Gln His Cys Leu Ala Arg Pro Thr Ser Gln
                 515                 520                 525

 Leu Pro His Gly Ser Gln Ala Ser Pro Ala Gln Ala Gln Glu Phe
                 530                 535                 540

 Pro Leu Glu Ala Gly Ile Ser His Leu Glu Ala Asp Leu Ser Gln
                 545                 550                 555

 Thr Ser Leu Val Leu Glu Thr Ser Ile Ala Glu Gln Leu Gln Glu
                 560                 565                 570

 Leu Pro Phe Thr Pro Leu His Ala Pro Ile Val Val Gly Thr Gln
                 575                 580                 585

 Thr Arg Ser Ser Ala Gly Gln Pro Ser Arg Ala Ser Met Val Leu
                 590                 595                 600

 Leu Gln Ser Ser Gly Phe Pro Glu Ile Leu Asp Ala Asn Lys Gln
                 605                 610                 615

 Pro Ala Glu Ala Val Ser Ala Thr Glu Pro Val Thr Phe Asn Pro
                 620                 625                 630

 Gln Lys Glu Glu Ser Asp Cys Leu Gln Ser Asn Glu Met Val Leu
                 635                 640                 645

 Gln Phe Leu Ala Phe Ser Arg Val Ala Gln Asp Cys Arg Gly Thr
                 650                 655                 660

 Ser Trp Pro Lys Thr Val Tyr Phe Thr Phe Gln Phe Tyr Arg Phe
                 665                 670                 675

 Pro Pro Ala Thr Thr Pro Arg Leu Gln Leu Val Gln Leu Asp Glu
                 680                 685                 690

 Ala Gly Gln Pro Ser Ser Gly Ala Leu Thr His Ile Leu Val Pro
                 695                 700                 705

 Val Ser Arg Asp Gly Thr Phe Asp Ala Gly Ser Pro Gly Phe Gln
                 710                 715                 720

 Leu Arg Tyr Met Val Gly Pro Gly Phe Leu Lys Pro Gly Glu Arg
                 725                 730                 735

 Arg Cys Phe Ala Arg Tyr Leu Ala Val Gln Thr Leu Gln Ile Asp
                 740                 745                 750

 Val Trp Asp Gly Asp Ser Leu Leu Leu Ile Gly Ser Ala Ala Val
                 755                 760                 765

 Gln Met Lys His Leu Leu Arg Gln Gly Arg Pro Ala Val Gln Ala
                 770                 775                 780

 Ser His Glu Leu Glu Val Val Ala Thr Glu Tyr Glu Gln Asp Asn
                 785                 790                 795

 Met Val Val Ser Gly Asp Met Leu Gly Phe Gly Arg Val Lys Pro
                 800                 805                 810

 Ile Gly Val His Ser Val Val Lys Gly Arg Leu His Leu Thr Leu
                 815                 820                 825

 Ala Asn Val Gly His Pro Cys Glu Gln Lys Val Arg Gly Cys Ser
                 830                 835                 840

 Thr Leu Pro Pro Ser Arg Ser Arg Val Ile Ser Asn Asp Gly Ala
                 845                 850                 855

 Ser Arg Phe Ser Gly Gly Ser Leu Leu Thr Thr Gly Ser Ser Arg
                 860                 865                 870

 Arg Lys His Val Val Gln Ala Gln Lys Leu Ala Asp Val Asp Ser
                 875                 880                 885

 Glu Leu Ala Ala Met Leu Leu Thr His Ala Arg Gln Gly Lys Gly
                 890                 895                 900

 Pro Gln Asp Val Ser Arg Glu Ser Asp Ala Thr Arg Arg Arg Lys
                 905                 910                 915

 Leu Glu Arg Met Arg Ser Val Arg Leu Gln Glu Ala Gly Gly Asp
                 920                 925                 930

 Leu Gly Arg Arg Gly Thr Ser Val Leu Ala Gln Gln Ser Val Arg
                 935                 940                 945

 Thr Gln His Leu Arg Asp Leu Gln Val Ile Ala Ala Tyr Arg Glu
                 950                 955                 960

 Arg Thr Lys Ala Glu Ser Ile Ala Ser Leu Leu Ser Leu Ala Ile
                 965                 970                 975

 Thr Thr Glu His Thr Leu His Ala Thr Leu Gly Val Ala Glu Phe
                 980                 985                 990

 Phe Glu Phe Val Leu Lys Asn Pro His Asn Thr Gln His Thr Val
                 995                1000                1005

 Thr Val Glu Ile Asp Asn Pro Glu Leu Ser Val Ile Val Asp Ser
                1010                1015                1020

 Gln Glu Trp Arg Asp Phe Lys Gly Ala Ala Gly Leu His Thr Pro
                1025                1030                1035

 Val Glu Glu Asp Met Phe His Leu Arg Gly Ser Leu Ala Pro Gln
                1040                1045                1050

 Leu Tyr Leu Arg Pro His Glu Thr Ala His Val Pro Phe Lys Phe
                1055                1060                1065

 Gln Ser Phe Ser Ala Gly Gln Leu Ala Met Val Gln Ala Ser Pro
                1070                1075                1080

 Gly Leu Ser Asn Glu Lys Gly Met Asp Ala Val Ser Pro Trp Lys
                1085                1090                1095

 Ser Ser Ala Val Pro Thr Lys His Ala Lys Val Leu Phe Arg Ala
                1100                1105                1110

 Ser Gly Gly Lys Pro Ile Ala Val Leu Cys Leu Thr Val Glu Leu
                1115                1120                1125

 Gln Pro His Val Val Asp Gln Val Phe Arg Phe Tyr His Pro Glu
                1130                1135                1140

 Leu Ser Phe Leu Lys Lys Ala Ile Arg Leu Pro Pro Trp His Thr
                1145                1150                1155

 Phe Pro Gly Ala Pro Val Gly Met Leu Gly Glu Asp Pro Pro Val
                1160                1165                1170

 His Val Arg Cys Ser Asp Pro Asn Val Ile Cys Glu Thr Gln Asn
                1175                1180                1185

 Val Gly Pro Gly Glu Pro Arg Asp Ile Phe Leu Lys Val Ala Ser
                1190                1195                1200

 Gly Pro Ser Pro Glu Ile Lys Asp Phe Phe Val Ile Ile Tyr Ser
                1205                1210                1215

 Asp Arg Trp Leu Ala Thr Pro Thr Gln Thr Trp Gln Val Tyr Leu
                1220                1225                1230

 His Ser Leu Gln Arg Val Asp Val Ser Cys Val Ala Gly Gln Leu
                1235                1240                1245

 Thr Arg Leu Ser Leu Val Leu Arg Gly Thr Gln Thr Val Arg Lys
                1250                1255                1260

 Val Arg Ala Phe Thr Ser His Pro Gln Glu Leu Lys Thr Asp Pro
                1265                1270                1275

 Lys Gly Val Phe Val Leu Pro Pro Arg Gly Val Gln Asp Leu His
                1280                1285                1290

 Val Gly Val Arg Pro Leu Arg Ala Gly Ser Arg Phe Val His Leu
                1295                1300                1305

 Asn Leu Val Asp Val Asp Cys His Gln Leu Val Ala Ser Trp Leu
                1310                1315                1320

 Val Cys Leu Cys Cys Arg Gln Pro Leu Ile Ser Lys Ala Phe Glu
                1325                1330                1335

 Ile Met Leu Ala Ala Gly Glu Gly Lys Gly Val Asn Lys Arg Ile
                1340                1345                1350

 Thr Tyr Thr Asn Pro Tyr Pro Ser Arg Arg Thr Phe His Leu His
                1355                1360                1365

 Ser Asp His Pro Glu Leu Leu Arg Phe Arg Glu Asp Ser Phe Gln
                1370                1375                1380

 Val Gly Gly Gly Glu Thr Tyr Thr Ile Gly Leu Gln Phe Ala Pro
                1385                1390                1395

 Ser Gln Arg Val Gly Glu Glu Glu Ile Leu Ile Tyr Ile Asn Asp
                1400                1405                1410

 His Glu Asp Lys Asn Glu Glu Ala Phe Cys Val Lys Val Ile Tyr
                1415                1420                1425

 Gln


<210> 2795
<211> 1648
<212> DNA
<213> Homo sapien

<400> 2795
 atgcgggaga tcgtgcacat ccaggccggc cagtgcggca accagatcgg 50

 ggccaagttc tgggaagtca tcagtgatga gcatggcatc gaccccagcg 100

 gcaactacgt gggcgactcg gacttgcagc tggagcggat cagcgtctac 150

 tacaacgagg cctcttctca caagtacgtg cctcgagcca ttctggtgga 200

 cctggaaccc ggaaccatgg acagtgtccg ctcaggggcc tttggacatc 250

 tcttcaggcc tgacaatttc atctttggtc agagtggggc cggcaacaac 300

 tgggccaagg gtcactacac ggagggggcg gagctggtgg attcggtcct 350

 ggatgtggtg cggaaggagt gtgaaaactg cgactgcctg cagggcttcc 400

 agctgaccca ctcgctgggg ggggggacgg gctccggcat gggcacgttg 450

 ctcatcagca aggtgcgtga ggagtatccc gaccgcatca tgaacacctt 500

 cagcgtcgtg ccctcaccca aggtgtcaga cacggtggtg gaaccctaca 550

 acgccacgct gtccatccac cagctggtgg aaaacacgga tgaaacctac 600

 tgcatcgaca acgaggcgct ctacgacatc tgcttccgca ccctcaagct 650

 ggccacgccc acctacgggg acctcaacca cctggtatcg gccaccatga 700

 gcggagtcac cacctccttg cgcttcccgg gccagctcaa cgctgacctg 750

 cgcaagctgg ccgtcaacat ggtgcccttc ccgcgcctgc acttcttcat 800

 gcccggcttc gcccccctca ccaggcgggg cagccagcag taccgggccc 850

 tgaccgtgcc cgagctcacc cagcagatgt tcgatgccaa gaacatgatg 900

 gccgcctgcg acccgcgcca cggccgctac ctgacggtgg ccaccgtgtt 950

 ccggggccgc atgtccatga aggaggtgga cgagcagatg ctggccatcc 1000

 agagcaagaa cagcagctac ttcgtggagt ggatccccaa caacgtgaag 1050

 gtggccgtgt gtgacatccc gccccgcggc ctcaagatgt cctccacctt 1100

 catcgggaac agcacggcca tccaggagct gttcaagcgc atctccgagc 1150

 agttcacggc catgttccgg cgcaaggcct tcctgcactg gtacacgggc 1200

 gagggcatgg acgagatgga gttcaccgag gccgagagca acatgaacga 1250

 cctggtgtcc gagtaccagc agtaccagga cgccacggcc gaggaagagg 1300

 gcgagatgta cgaagacgac gaggaggagt cggaggccca gggccccaag 1350

 tgaaactgct cgcagctgga gtgagaggca ggtggcggcc ggggccgaag 1400

 ccagcagtgt ctaaaccccc ggagccatct tgctgccgac accctgcttt 1450

 ccccatcgcc ctagggctcc cttgccgccc tcctgcagta tttatggcct 1500

 cgtcctcccc cacctaggcc acgtgtgagc tgctcctgtc tctgtcttat 1550

 tgcagctcca ggcctgacgt tttacggttt tgttttttac tggtttgtgt 1600

 ttatattttc ggggatactt aataaatcta ttgctgtcag ataccctt 1648

<210> 2796
<211> 450
<212> PRT
<213> Homo sapien

<400> 2796
 Met Arg Glu Ile Val His Ile Gln Ala Gly Gln Cys Gly Asn Gln
   1               5                  10                  15

 Ile Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile
                  20                  25                  30

 Asp Pro Ser Gly Asn Tyr Val Gly Asp Ser Asp Leu Gln Leu Glu
                  35                  40                  45

 Arg Ile Ser Val Tyr Tyr Asn Glu Ala Ser Ser His Lys Tyr Val
                  50                  55                  60

 Pro Arg Ala Ile Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser
                  65                  70                  75

 Val Arg Ser Gly Ala Phe Gly His Leu Phe Arg Pro Asp Asn Phe
                  80                  85                  90

 Ile Phe Gly Gln Ser Gly Ala Gly Asn Asn Trp Ala Lys Gly His
                  95                 100                 105

 Tyr Thr Glu Gly Ala Glu Leu Val Asp Ser Val Leu Asp Val Val
                 110                 115                 120

 Arg Lys Glu Cys Glu Asn Cys Asp Cys Leu Gln Gly Phe Gln Leu
                 125                 130                 135

 Thr His Ser Leu Gly Gly Gly Thr Gly Ser Gly Met Gly Thr Leu
                 140                 145                 150

 Leu Ile Ser Lys Val Arg Glu Glu Tyr Pro Asp Arg Ile Met Asn
                 155                 160                 165

 Thr Phe Ser Val Val Pro Ser Pro Lys Val Ser Asp Thr Val Val
                 170                 175                 180

 Glu Pro Tyr Asn Ala Thr Leu Ser Ile His Gln Leu Val Glu Asn
                 185                 190                 195

 Thr Asp Glu Thr Tyr Cys Ile Asp Asn Glu Ala Leu Tyr Asp Ile
                 200                 205                 210

 Cys Phe Arg Thr Leu Lys Leu Ala Thr Pro Thr Tyr Gly Asp Leu
                 215                 220                 225

 Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Ser Leu
                 230                 235                 240

 Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val
                 245                 250                 255

 Asn Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe
                 260                 265                 270

 Ala Pro Leu Thr Arg Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr
                 275                 280                 285

 Val Pro Glu Leu Thr Gln Gln Met Phe Asp Ala Lys Asn Met Met
                 290                 295                 300

 Ala Ala Cys Asp Pro Arg His Gly Arg Tyr Leu Thr Val Ala Thr
                 305                 310                 315

 Val Phe Arg Gly Arg Met Ser Met Lys Glu Val Asp Glu Gln Met
                 320                 325                 330

 Leu Ala Ile Gln Ser Lys Asn Ser Ser Tyr Phe Val Glu Trp Ile
                 335                 340                 345

 Pro Asn Asn Val Lys Val Ala Val Cys Asp Ile Pro Pro Arg Gly
                 350                 355                 360

 Leu Lys Met Ser Ser Thr Phe Ile Gly Asn Ser Thr Ala Ile Gln
                 365                 370                 375

 Glu Leu Phe Lys Arg Ile Ser Glu Gln Phe Thr Ala Met Phe Arg
                 380                 385                 390

 Arg Lys Ala Phe Leu His Trp Tyr Thr Gly Glu Gly Met Asp Glu
                 395                 400                 405

 Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn Asp Leu Val Ser
                 410                 415                 420

 Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Glu Glu Glu Gly Glu
                 425                 430                 435

 Met Tyr Glu Asp Asp Glu Glu Glu Ser Glu Ala Gln Gly Pro Lys
                 440                 445                 450

<210> 2797
<211> 4205
<212> DNA
<213> Homo sapien

<400> 2797
 ctccctcgct ccctccctgc gcgccgcctc tcactcacag cctcccttcc 50

 ttctttctcc ctccgcctcc cgagcaccag cgcgctctga gctgccccca 100

 gggtccctcc cccgccgcca gcagcccatt tggagggagg aagtaaggga 150

 agaggagagg aaggggagcc ggaccgacta cccagacaga gccggtgaat 200

 gggtttgtgg tgacccccgc cccccacccc accctccctt cccacccgac 250

 ccccaacccc catccccagt tcgagccgcc gcccgaaagg ccgggccgtc 300

 gtcttaggag gagtcgccgc cgccgccacc tccgccatgg agctgatcac 350

 cattctcgag aagaccgtgt ctcccgatcg gctggagctg gaagcggcgc 400

 agaagttcct ggagcgtgcg gccgtggaga acctgcccac tttccttgtg 450

 gaactgtcca gagtgctggc aaatccagga aacagtcagg ttgccagagt 500

 tgcagctggt ctacaaatca agaactcttt gacatctaaa gatccagata 550

 tcaaggcaca atatcagcag aggtggcttg ctattgatgc taatgctcga 600

 cgagaagtca agaactatgt tttgcagaca ttgggtacag aaacttaccg 650

 gcctagttct gcctcacagt gtgtggctgg tattgcttgt gcagagatcc 700

 cagtaaacca gtggccagaa ctcattcctc agctggtggc caatgtcaca 750

 aaccccaaca gcacagagca catgaaggag tcgacattgg aagccatcgg 800

 ttatatttgc caagatatag acccagagca gctacaagat aaatccaatg 850

 agattctgac tgccataatc caggggatga ggaaagaaga gcctagtaat 900

 aatgtgaagc tagctgctac gaatgcactc ctgaactcat tggagttcac 950

 caaagcaaac tttgataaag agtctgaaag gcactttatt atgcaggtgg 1000

 tctgtgaagc cacacagtgt ccagatacga gggtacgagt ggctgcttta 1050

 cagaatctgg tgaagataat gtccttatat tatcagtaca tggagacata 1100

 tatgggtcct gctctttttg caatcacaat cgaagcaatg aaaagtgaca 1150

 ttgatgaggt ggctttacaa gggatagaat tctggtccaa tgtctgtgat 1200

 gaggaaatgg atttggccat tgaagcttca gaggcagcag aacaaggacg 1250

 gccccctgag cacaccagca agttttatgc gaagggagca ctacagtatc 1300

 tggttccaat cctcacacag acactaacta aacaggacga aaatgatgat 1350

 gacgatgact ggaacccctg caaagcagca ggggtgtgcc tcatgcttct 1400

 ggccacctgc tgtgaagatg acattgtccc acatgtcctc cccttcatta 1450

 aagaacacat caagaaccca gattggcggt accgggatgc agcagtgatg 1500

 gcttttggtt gtatcttgga aggaccagag cccagtcagc tcaaaccact 1550

 agttatacag gctatgccca ccctaataga attaatgaaa gaccccagtg 1600

 tagttgttcg agatacagct gcatggactg taggcagaat ttgtgagctg 1650

 cttcctgaag ctgccatcaa tgatgtctac ttggctcccc tgctacagtg 1700

 tctgattgag ggtctcagtg ctgaacccag agtggcttca aatgtgtgct 1750

 gggctttctc cagtctggct gaagctgctt atgaagctgc agacgttgct 1800

 gatgatcagg aagaaccagc tacttactgc ttatcttctt catttgaact 1850

 catagttcag aagctcctag agactacaga cagacctgat ggacaccaga 1900

 acaacctgag gagttctgca tatgaatctc tgatggaaat tgtgaaaaac 1950

 agtgccaagg attgttatcc tgctgtccag aaaacgactt tggtcatcat 2000

 ggaacgactg caacaggttc ttcagatgga gtcacatatc cagagcacat 2050

 ccgatagaat ccagttcaat gaccttcagt ctttactctg tgcaactctt 2100

 cagaatgttc ttcggaaagt gcaacatcaa gatgctttgc agatctctga 2150

 tgtggttatg gcctccctgt taaggatgtt ccaaagcaca gctgggtctg 2200

 ggggagtaca agaggatgcc ctgatggcag ttagcacact ggtggaagtg 2250

 ttgggtggtg aattcctcaa gtacatggag gcctttaaac ccttcctggg 2300

 cattggatta aaaaattatg ctgaatacca ggtttgtttg gcagctgtgg 2350

 gcttagtggg agacttgtgc cgtgccctgc aatccaacat catacctttc 2400

 tgtgacgagg tgatgcagct gcttctggaa aatttgggga atgagaacgt 2450

 ccacaggtct gtgaagccgc agattctgtc agtgtttggt gatattgccc 2500

 ttgctattgg aggagagttt aaaaaatact tagaggttgt attgaatact 2550

 cttcagcagg cctcccaagc ccaggtggac aagtcagact atgacatggt 2600

 ggattatctg aatgagctaa gggaaagctg cttggaagcc tatactggaa 2650

 tcgtccaggg attaaagggg gatcaggaga acgtacaccc ggatgtgatg 2700

 ctggtacaac ccagagtaga atttattctg tctttcattg accacattgc 2750

 tggagatgag gatcacacag atggagtagt agcttgtgct gctggactaa 2800

 taggggactt atgtacagca tttgggaagg atgtactgaa attagtagaa 2850

 gctaggccaa tgatccatga attgttaact gaagggcgga gatcgaagac 2900

 taacaaagca aaaacccttg ctacatgggc aacaaaagaa ctgaggaaac 2950

 tgaagaacca agcttgatct gttaccattg ggatgataac ctgaggaccc 3000

 ccactggaaa tctcccatct tttgaaaaac ctggaagtga ggagtgtgca 3050

 cggatgctga atgtttggga atgagaggat gagtgagtga ggcttgaaaa 3100

 cacaccacat tgaaaatcct gccacagcag cagccgcagc cgccaacagc 3150

 agcgctgtta gtgagctaag taagcactga cttcgtagaa aaccataaca 3200

 tcggccatct tggaaaagag aaaaacaatg gagttactta tttaaaaaaa 3250

 aagaaagaaa gttatctctt cccaggagag gctagaagta gcttttctgt 3300

 cttttggcca gtgccgagtg gaatgcctgg tttgggggag gaggagggac 3350

 tgggttcagc tgtggtgctt tgttgtaaaa ggcagcctgg cctttgctac 3400

 tgaggagaaa gatggagcct gggtctcaag cccaccttcg ctgtaccttt 3450

 gccacatggt actgtatgct tgccagctag aaggagggtc agggattttt 3500

 tacagtctga gaatgagtgt gtgtgagtga ggcggtatcc acattctcaa 3550

 cttcaagtca ttgcagtttc tttttcccag aaaacaaggg gttagatgtt 3600

 gcatttcata aaactaaccg aagttctgtc tactgatgca gcacaagaga 3650

 tgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aacacacaca cagaggaaag 3700

 acgctcttta ggttttgttt tgtttttttt ttttggtttt gttttttgtt 3750

 ttttttactc tagggaaaac actgacgaat ggtcagagct cctatcctga 3800

 tcttttcatc aaggcgcctt tcctaataat atggttcaac tgtgaatgta 3850

 gaagtggggg ggagggggga gaaaaagaaa actctggcgt tagaggatat 3900

 agaaaaatat aagtacaatt gttacaaata acgcagactt caaaaacaaa 3950

 aaaatcacaa cccaaacaaa ccaaaattta aatgatcaga attggcagca 4000

 caaagaaaac gccctctcct gacttgtatt gtggcagtct gaacgccccc 4050

 agaaaattgt gccaaagagt ttagaaaaat aaatatacaa taaaagtaaa 4100

 cacatacaca caaaacagca aacttcaggt aactattttg gattgcaaac 4150

 aggataaatt aaatgttcaa acaatctgat aaaataacca tttggaaact 4200

 gaaaa 4205

<210> 2798
<211> 876
<212> PRT
<213> Homo sapien

<400> 2798
 Met Glu Leu Ile Thr Ile Leu Glu Lys Thr Val Ser Pro Asp Arg
   1               5                  10                  15

 Leu Glu Leu Glu Ala Ala Gln Lys Phe Leu Glu Arg Ala Ala Val
                  20                  25                  30

 Glu Asn Leu Pro Thr Phe Leu Val Glu Leu Ser Arg Val Leu Ala
                  35                  40                  45

 Asn Pro Gly Asn Ser Gln Val Ala Arg Val Ala Ala Gly Leu Gln
                  50                  55                  60

 Ile Lys Asn Ser Leu Thr Ser Lys Asp Pro Asp Ile Lys Ala Gln
                  65                  70                  75

 Tyr Gln Gln Arg Trp Leu Ala Ile Asp Ala Asn Ala Arg Arg Glu
                  80                  85                  90

 Val Lys Asn Tyr Val Leu Gln Thr Leu Gly Thr Glu Thr Tyr Arg
                  95                 100                 105

 Pro Ser Ser Ala Ser Gln Cys Val Ala Gly Ile Ala Cys Ala Glu
                 110                 115                 120

 Ile Pro Val Asn Gln Trp Pro Glu Leu Ile Pro Gln Leu Val Ala
                 125                 130                 135

 Asn Val Thr Asn Pro Asn Ser Thr Glu His Met Lys Glu Ser Thr
                 140                 145                 150

 Leu Glu Ala Ile Gly Tyr Ile Cys Gln Asp Ile Asp Pro Glu Gln
                 155                 160                 165

 Leu Gln Asp Lys Ser Asn Glu Ile Leu Thr Ala Ile Ile Gln Gly
                 170                 175                 180

 Met Arg Lys Glu Glu Pro Ser Asn Asn Val Lys Leu Ala Ala Thr
                 185                 190                 195

 Asn Ala Leu Leu Asn Ser Leu Glu Phe Thr Lys Ala Asn Phe Asp
                 200                 205                 210

 Lys Glu Ser Glu Arg His Phe Ile Met Gln Val Val Cys Glu Ala
                 215                 220                 225

 Thr Gln Cys Pro Asp Thr Arg Val Arg Val Ala Ala Leu Gln Asn
                 230                 235                 240

 Leu Val Lys Ile Met Ser Leu Tyr Tyr Gln Tyr Met Glu Thr Tyr
                 245                 250                 255

 Met Gly Pro Ala Leu Phe Ala Ile Thr Ile Glu Ala Met Lys Ser
                 260                 265                 270

 Asp Ile Asp Glu Val Ala Leu Gln Gly Ile Glu Phe Trp Ser Asn
                 275                 280                 285

 Val Cys Asp Glu Glu Met Asp Leu Ala Ile Glu Ala Ser Glu Ala
                 290                 295                 300

 Ala Glu Gln Gly Arg Pro Pro Glu His Thr Ser Lys Phe Tyr Ala
                 305                 310                 315

 Lys Gly Ala Leu Gln Tyr Leu Val Pro Ile Leu Thr Gln Thr Leu
                 320                 325                 330

 Thr Lys Gln Asp Glu Asn Asp Asp Asp Asp Asp Trp Asn Pro Cys
                 335                 340                 345

 Lys Ala Ala Gly Val Cys Leu Met Leu Leu Ala Thr Cys Cys Glu
                 350                 355                 360

 Asp Asp Ile Val Pro His Val Leu Pro Phe Ile Lys Glu His Ile
                 365                 370                 375

 Lys Asn Pro Asp Trp Arg Tyr Arg Asp Ala Ala Val Met Ala Phe
                 380                 385                 390

 Gly Cys Ile Leu Glu Gly Pro Glu Pro Ser Gln Leu Lys Pro Leu
                 395                 400                 405

 Val Ile Gln Ala Met Pro Thr Leu Ile Glu Leu Met Lys Asp Pro
                 410                 415                 420

 Ser Val Val Val Arg Asp Thr Ala Ala Trp Thr Val Gly Arg Ile
                 425                 430                 435

 Cys Glu Leu Leu Pro Glu Ala Ala Ile Asn Asp Val Tyr Leu Ala
                 440                 445                 450

 Pro Leu Leu Gln Cys Leu Ile Glu Gly Leu Ser Ala Glu Pro Arg
                 455                 460                 465

 Val Ala Ser Asn Val Cys Trp Ala Phe Ser Ser Leu Ala Glu Ala
                 470                 475                 480

 Ala Tyr Glu Ala Ala Asp Val Ala Asp Asp Gln Glu Glu Pro Ala
                 485                 490                 495

 Thr Tyr Cys Leu Ser Ser Ser Phe Glu Leu Ile Val Gln Lys Leu
                 500                 505                 510

 Leu Glu Thr Thr Asp Arg Pro Asp Gly His Gln Asn Asn Leu Arg
                 515                 520                 525

 Ser Ser Ala Tyr Glu Ser Leu Met Glu Ile Val Lys Asn Ser Ala
                 530                 535                 540

 Lys Asp Cys Tyr Pro Ala Val Gln Lys Thr Thr Leu Val Ile Met
                 545                 550                 555

 Glu Arg Leu Gln Gln Val Leu Gln Met Glu Ser His Ile Gln Ser
                 560                 565                 570

 Thr Ser Asp Arg Ile Gln Phe Asn Asp Leu Gln Ser Leu Leu Cys
                 575                 580                 585

 Ala Thr Leu Gln Asn Val Leu Arg Lys Val Gln His Gln Asp Ala
                 590                 595                 600

 Leu Gln Ile Ser Asp Val Val Met Ala Ser Leu Leu Arg Met Phe
                 605                 610                 615

 Gln Ser Thr Ala Gly Ser Gly Gly Val Gln Glu Asp Ala Leu Met
                 620                 625                 630

 Ala Val Ser Thr Leu Val Glu Val Leu Gly Gly Glu Phe Leu Lys
                 635                 640                 645

 Tyr Met Glu Ala Phe Lys Pro Phe Leu Gly Ile Gly Leu Lys Asn
                 650                 655                 660

 Tyr Ala Glu Tyr Gln Val Cys Leu Ala Ala Val Gly Leu Val Gly
                 665                 670                 675

 Asp Leu Cys Arg Ala Leu Gln Ser Asn Ile Ile Pro Phe Cys Asp
                 680                 685                 690

 Glu Val Met Gln Leu Leu Leu Glu Asn Leu Gly Asn Glu Asn Val
                 695                 700                 705

 His Arg Ser Val Lys Pro Gln Ile Leu Ser Val Phe Gly Asp Ile
                 710                 715                 720

 Ala Leu Ala Ile Gly Gly Glu Phe Lys Lys Tyr Leu Glu Val Val
                 725                 730                 735

 Leu Asn Thr Leu Gln Gln Ala Ser Gln Ala Gln Val Asp Lys Ser
                 740                 745                 750

 Asp Tyr Asp Met Val Asp Tyr Leu Asn Glu Leu Arg Glu Ser Cys
                 755                 760                 765

 Leu Glu Ala Tyr Thr Gly Ile Val Gln Gly Leu Lys Gly Asp Gln
                 770                 775                 780

 Glu Asn Val His Pro Asp Val Met Leu Val Gln Pro Arg Val Glu
                 785                 790                 795

 Phe Ile Leu Ser Phe Ile Asp His Ile Ala Gly Asp Glu Asp His
                 800                 805                 810

 Thr Asp Gly Val Val Ala Cys Ala Ala Gly Leu Ile Gly Asp Leu
                 815                 820                 825

 Cys Thr Ala Phe Gly Lys Asp Val Leu Lys Leu Val Glu Ala Arg
                 830                 835                 840

 Pro Met Ile His Glu Leu Leu Thr Glu Gly Arg Arg Ser Lys Thr
                 845                 850                 855

 Asn Lys Ala Lys Thr Leu Ala Thr Trp Ala Thr Lys Glu Leu Arg
                 860                 865                 870

 Lys Leu Lys Asn Gln Ala
                 875

<210> 2799
<211> 1958
<212> DNA
<213> Homo sapien

<400> 2799
 agcagccggc gcggccgcca gcgcggtgta gggggcaggc gcggatcccg 50

 ccaccgccgc gcgctcggcc cgccgactcc cggcgccgcc gccgccactg 100

 ccgtcgccgc cgccgcctgc cgggactgga gcgcgccgtc cgccgcggac 150

 aagaccctgg cctcaggccg gagcagcccc atcatgccga gggagcgcag 200

 ggagcgggat gcgaaggagc gggacaccat gaaggaggac ggcggcgcgg 250

 agttctcggc tcgctccagg aagaggaagg caaacgtgac cgtttttttg 300

 caggatccag atgaagaaat ggccaaaatc gacaggacgg cgagggacca 350

 gtgtgggagc cagccttggg acaataatgc agtctgtgca gacccctgct 400

 ccctgatccc cacacctgac aaagaagatg atgaccgggt ttacccaaac 450

 tcaacgtgca agcctcggat tattgcacca tccagaggct ccccgctgcc 500

 tgtactgagc tgggcaaata gagaggaagt ctggaaaatc atgttaaaca 550

 aggaaaagac atacttaagg gatcagcact ttcttgagca acaccctctt 600

 ctgcagccaa aaatgcgagc aattcttctg gattggttaa tggaggtgtg 650

 tgaagtctat aaacttcaca gggagacctt ttacttggca caagatttct 700

 ttgaccggta tatggcgaca caagaaaatg ttgtaaaaac tcttttacag 750

 cttattggga tttcatcttt atttattgca gccaaacttg aggaaatcta 800

 tcctccaaag ttgcaccagt ttgcgtatgt gacagatgga gcttgttcag 850

 gagatgaaat tctcaccatg gaattaatga ttatgaaggc ccttaagtgg 900

 cgtttaagtc ccctgactat tgtgtcctgg ctgaatgtat acatgcaggt 950

 tgcatatcta aatgacttac atgaagtgct actgccgcag tatccccagc 1000

 aaatctttat acagattgca gagctgttgg atctctgtgt cctggatgtt 1050

 gactgccttg aatttcctta tggtatactt gctgcttcgg ccttgtatca 1100

 tttctcgtca tctgaattga tgcaaaaggt ttcagggtat cagtggtgcg 1150

 acatagagaa ctgtgtcaag tggatggttc catttgccat ggttataagg 1200

 gagacgggga gctcaaaact gaagcacttc aggggcgtcg ctgatgaaga 1250

 tgcacacaac atacagaccc acagagacag cttggatttg ctggacaaag 1300

 cccgagcaaa gaaagccatg ttgtctgaac aaaatagggc ttctcctctc 1350

 cccagtgggc tcctcacccc gccacagagc ggtaagaagc agagcagcgg 1400

 gccggaaatg gcgtgaccac cccatccttc tccaccaaag acagttgcgc 1450

 gcctgctcca cgttctcttc tgtctgttgc agcggaggcg tgcgtttgct 1500

 tttacagata tctgaatgga agagtgtttc ttccacaaca gaagtatttc 1550

 tgtggatggc atcaaacagg gcaaagtgtt ttttattgaa tgcttatagg 1600

 ttttttttaa ataagtgggt caagtacacc agccacctcc agacaccagt 1650

 gcgtgctccc gatgctgcta tggaaggtgc tacttgacct aagggactcc 1700

 cacaacaaca aaagcttgaa gctgtggagg gccacggtgg cgtggctctc 1750

 ctcgcaggtg ttctgggctc cgttgtacca agtggagcag gtggttgcgg 1800

 gcaagcgttg tgcagagccc atagccagct gggcaggggg ctgccctctc 1850

 cacattatca gttgacagtg tacaatgcct ttgatgaact gttttgtaag 1900

 tgctgctata tctatccatt ttttaataaa gataatactg tttttgagac 1950

 aaaaaaaa 1958

<210> 2800
<211> 410
<212> PRT
<213> Homo sapien

<400> 2800
 Met Pro Arg Glu Arg Arg Glu Arg Asp Ala Lys Glu Arg Asp Thr
   1               5                  10                  15

 Met Lys Glu Asp Gly Gly Ala Glu Phe Ser Ala Arg Ser Arg Lys
                  20                  25                  30

 Arg Lys Ala Asn Val Thr Val Phe Leu Gln Asp Pro Asp Glu Glu
                  35                  40                  45

 Met Ala Lys Ile Asp Arg Thr Ala Arg Asp Gln Cys Gly Ser Gln
                  50                  55                  60

 Pro Trp Asp Asn Asn Ala Val Cys Ala Asp Pro Cys Ser Leu Ile
                  65                  70                  75

 Pro Thr Pro Asp Lys Glu Asp Asp Asp Arg Val Tyr Pro Asn Ser
                  80                  85                  90

 Thr Cys Lys Pro Arg Ile Ile Ala Pro Ser Arg Gly Ser Pro Leu
                  95                 100                 105

 Pro Val Leu Ser Trp Ala Asn Arg Glu Glu Val Trp Lys Ile Met
                 110                 115                 120

 Leu Asn Lys Glu Lys Thr Tyr Leu Arg Asp Gln His Phe Leu Glu
                 125                 130                 135

 Gln His Pro Leu Leu Gln Pro Lys Met Arg Ala Ile Leu Leu Asp
                 140                 145                 150

 Trp Leu Met Glu Val Cys Glu Val Tyr Lys Leu His Arg Glu Thr
                 155                 160                 165

 Phe Tyr Leu Ala Gln Asp Phe Phe Asp Arg Tyr Met Ala Thr Gln
                 170                 175                 180

 Glu Asn Val Val Lys Thr Leu Leu Gln Leu Ile Gly Ile Ser Ser
                 185                 190                 195

 Leu Phe Ile Ala Ala Lys Leu Glu Glu Ile Tyr Pro Pro Lys Leu
                 200                 205                 210

 His Gln Phe Ala Tyr Val Thr Asp Gly Ala Cys Ser Gly Asp Glu
                 215                 220                 225

 Ile Leu Thr Met Glu Leu Met Ile Met Lys Ala Leu Lys Trp Arg
                 230                 235                 240

 Leu Ser Pro Leu Thr Ile Val Ser Trp Leu Asn Val Tyr Met Gln
                 245                 250                 255

 Val Ala Tyr Leu Asn Asp Leu His Glu Val Leu Leu Pro Gln Tyr
                 260                 265                 270

 Pro Gln Gln Ile Phe Ile Gln Ile Ala Glu Leu Leu Asp Leu Cys
                 275                 280                 285

 Val Leu Asp Val Asp Cys Leu Glu Phe Pro Tyr Gly Ile Leu Ala
                 290                 295                 300

 Ala Ser Ala Leu Tyr His Phe Ser Ser Ser Glu Leu Met Gln Lys
                 305                 310                 315

 Val Ser Gly Tyr Gln Trp Cys Asp Ile Glu Asn Cys Val Lys Trp
                 320                 325                 330

 Met Val Pro Phe Ala Met Val Ile Arg Glu Thr Gly Ser Ser Lys
                 335                 340                 345

 Leu Lys His Phe Arg Gly Val Ala Asp Glu Asp Ala His Asn Ile
                 350                 355                 360

 Gln Thr His Arg Asp Ser Leu Asp Leu Leu Asp Lys Ala Arg Ala
                 365                 370                 375

 Lys Lys Ala Met Leu Ser Glu Gln Asn Arg Ala Ser Pro Leu Pro
                 380                 385                 390

 Ser Gly Leu Leu Thr Pro Pro Gln Ser Gly Lys Lys Gln Ser Ser
                 395                 400                 405

 Gly Pro Glu Met Ala
                 410

<210> 2801
<211> 879
<212> DNA
<213> Homo sapien

<400> 2801
 gcggagtctc caactgggag agctgcagct gccgagagga ggagaacgct 50

 gaggtcggtc ggaccaacgg acgcgctgac cgctgccaac tgcagctcgc 100

 gctgcctcct gctcgcgccg tgccactaag gtcactcccg cctccgagag 150

 cccagagccg agatggaaac ggtccaggag ctgatccccc tggccaagga 200

 gatgatggcc cagaagcgca aggggaagat ggtgaagctg tacgtgctgg 250

 gcagcgtgct ggccctcttc ggcgtggtgc tcggcctgat ggagactgtg 300

 tgcagcccct tcacggccgc cagacgtctg cgggaccagg aggcagccgt 350

 ggcggagctg caggccgccc tggagcgaca ggctctccag aagcaagccc 400

 tgcaggagaa aggcaagcag caggacacgg tcctcggcgg ccgggccctg 450

 tccaaccggc agcacgcctc ctaggaactg tgggagacca gcggagtggg 500

 agggagacgc agtagacaga gacagaccga gaaggaaggg agagacagag 550

 ggggcgcgcg cacaggagcc tgactccgct gggagagtgc aggagcacgt 600

 gctgtttttt atttggactt aacttcagag aaaccgctga catctagaac 650

 tgacctacca caagcatcca ccaaaggagt ttgggattga gttttgctgc 700

 tgtgcagcac tgcattgtca tgacatttcc aacactgtgt gaattatcta 750

 aatgcgtcta ccattttgca ctagggagga aggataaatg ctttttatgt 800

 tattattatt aattattaca atgaccacca ttttgcattt tgaaataaaa 850

 aactttttat accaaaaaaa aaaaaaaaa 879

<210> 2802
<211> 103
<212> PRT
<213> Homo sapien

<400> 2802
 Met Glu Thr Val Gln Glu Leu Ile Pro Leu Ala Lys Glu Met Met
   1               5                  10                  15

 Ala Gln Lys Arg Lys Gly Lys Met Val Lys Leu Tyr Val Leu Gly
                  20                  25                  30

 Ser Val Leu Ala Leu Phe Gly Val Val Leu Gly Leu Met Glu Thr
                  35                  40                  45

 Val Cys Ser Pro Phe Thr Ala Ala Arg Arg Leu Arg Asp Gln Glu
                  50                  55                  60

 Ala Ala Val Ala Glu Leu Gln Ala Ala Leu Glu Arg Gln Ala Leu
                  65                  70                  75

 Gln Lys Gln Ala Leu Gln Glu Lys Gly Lys Gln Gln Asp Thr Val
                  80                  85                  90

 Leu Gly Gly Arg Ala Leu Ser Asn Arg Gln His Ala Ser
                  95                 100

<210> 2803
<211> 2840
<212> DNA
<213> Homo sapien

<400> 2803
 gagtgaagac tataatctct acaatcagtt caagtctgca ccatctgaca 50

 gtttaacata caaactggct ttgtgtctct gtatgatcaa tttttaccat 100

 ggagggttga aaggagtggc acacctctgg caggaatttg ttcttgaaat 150

 gcgtttccga tgggaaaaca actttctgat tccaggatta gcaagtggac 200

 ccccagatct gaggtgttgt ttactgcatc agaaactaca gatgttaaat 250

 tgttgtattg aaagaaagaa ggcacgtgat gaggggaaaa agacaagtgc 300

 ttcagatgtc actaatatat atccagggga tgctggaaaa gcaggagacc 350

 agttggtgcc agataatcta aaagaaacag ataaggaaaa gggagaggta 400

 ggaaaatctt gggattcctg gagtgacagc gaagaagaat tttttgaatg 450

 cctaagtgat actgaagaac ttaaaggaag tggacaagag agtggcaaga 500

 aaggaggacc taaggagatg gcaaatttaa ggccggaagg acggctctat 550

 cagcatggga aacttacact gctgcataat ggagaacctc tctacattcc 600

 agtaacccag gaaccagcac ctatgacaga agatctgcta gaagagcagt 650

 ctgaagtttt agctaaatta ggtacatcgg cagagggggc tcaccttcga 700

 gcacgcatgc agagtgcctg tctgctctca gatatggagt cttttaaggc 750

 agctaatcca ggttgctccc tggaagattt tgtgaggtgg tattcacccc 800

 gggattatat tgaagaggag gtgattgatg aaaagggcaa tgtggtgctg 850

 aaaggagaac tgagtgcccg gatgaagatt ccaagcaata tgtgggtaga 900

 agcctgggaa acagctaagc caattcctgc tagaaggcaa aggagactct 950

 tcgatgatac acgggaagca gaaaaggtgc tgcactatct ggcaatccag 1000

 aaacctgcag accttgctcg gcacctgtta ccttgtgtga ttcatgcagc 1050

 tgtactcaag gtaaaggaag aagaaagtct cgaaaacatt tcttcagtta 1100

 agaagatcat aaagcagata atatcccatt ccagtaaagt tttgcacttc 1150

 cccaatccag aagacaagaa attggaagaa atcattcacc agattactaa 1200

 tgtggaagct ctcattgcca gagctcggtc actaaaagcc aagtttggaa 1250

 ctgagaaatg tgaacaggag gaggaaaagg aagatcttga aaggtttgtg 1300

 agttgcctgc tggagcagcc tgaagtgtta gtcaccggtg caggaagagg 1350

 acatgctggc aggatcattc acaagctgtt tgtgaatgcc cagagggctg 1400

 cagctatgac tccaccagag gaggaattga agagaatggg ctccccagag 1450

 gaaagaaggc agaactccgt gtcagacttc ccaccccctg ctggccggga 1500

 attcattttg cgcaccactg tgccgcgccc tgctccctac tccaaagctc 1550

 tgcctcagcg gatgtacagt gttctcacca aagaggactt tagacttgca 1600

 ggtgcctttt catcagatac ttccttcttc tgattcttct agcattactc 1650

 gttggtggct tcagagacag tgctgcctcc tcctgaggga gggaaggtac 1700

 cagggagaac ctgggaggtc ctggagaggg ccctgtccag ttgggtgatc 1750

 aggaatcaaa ccagcatcgg aaagacttcc cagcaccaag cttgagctgt 1800

 gtcgtttcgt ggagggggca gcgaggatgg gcttgagctg ttgagagatt 1850

 tctgccctag agatggcctt tgtatatggg ggggtggtgg ggggacacaa 1900

 acacatcaga cactccgtcc tcacactggc aggacggtgt tcatcgcatt 1950

 ctcttctgtg accagcctct aggctagcgg ctgcattcgt ggtctgtgca 2000

 aacacttcgt ggttctatat atcagcagca agtgtgcaaa ataaaggacc 2050

 tgttaactca gatttctgga tattttggtg gtagcttcta gtcccagaat 2100

 ctgtgttttt aaaatactac atgacattct gtctattcaa tcacctggtg 2150

 gtcatctttc ttgtactaat taactgttga tgagcatttt ggatattcta 2200

 ggagaaagcc tataatttca catagtttct ctttttcatg taactgtaac 2250

 ctaaatgtat tacttctgat aaaactatat atcaaatgtc actgcaaatt 2300

 agttttatat ctgtcatgtg agatttgtct tacttatttt tcttttggtt 2350

 gccatggaag ttatggccct gaaaatcgtc tccctcccct tctcttgctg 2400

 tacagcatgc gttctctttt tgtggttgct ggctgggtac tgtatttaat 2450

 gaagtagaga atagcacttg caaaaataca gtcttggtac ctagagactg 2500

 tcatgcagat agtataattt ggtatatgtg ctaatgcatt gagtagagga 2550

 ttattttaac acactatttt gcttttgtat tttagttaaa ataatcgatg 2600

 gggatgtgta gcccccccgt gtgaggatga catcaccaca tttctagttt 2650

 catggagctc aagatgtctt gtgtctgtgt ggctagatgg cctctgcttg 2700

 gtaatcttat ttttaggcct aaaattccca cttaaatcca aagtaaaaat 2750

 ggttatactg aagcataaac cttgcctgtg taattttaaa aaattaatag 2800

 agctgtgcaa accctgttat ttttgtaaaa aaaaaaaaaa 2840

<210> 2804
<211> 4704
<212> DNA
<213> Homo sapien

<400> 2804
 ttcatgattt tatatagaga atcttggaaa aaattattat taatctttgt 50

 aagtcacttg atcgttaata ttctaggaga aatttctttt taaaggaaca 100

 ctgataaatc atttataaaa taattttctc ttggttgcat tcacttttat 150

 gtttttcttt gattgtatgg aggatattta tagggcagaa aaaggggaaa 200

 atatccctgt cgttagtaaa tataatgata gctattgatt aaggtaaata 250

 ttttgccatt ttattggtac atatagggta tatttacttc tggcacatgg 300

 gaagagaaat cagatgaaat ttcctttgct gacttcaagt tctcagtcac 350

 tcatcattat cttgtacaag agtccactga taaagaagga aaggatgagt 400

 tattagagga tgttgttcca caatctatgc aagatttgct gggtatgaat 450

 aatgactttc ctccaagagc acattgcctg gtaagatggt atgggctacg 500

 tgagttcatg gtgattgccc ctgctgcaca cagtgacgct gttctcagcg 550

 aatctaagtg caaccttctt ctgagttctg tttctattgc cttgggaaac 600

 actggctgtc aggtgccact ctttgtgcaa attcaccaca aatggcgaag 650

 aatgtatgta ggagaatgtc aaggtcctgg tgtacgaact gatttcgaaa 700

 tggttcatct tagaaaagtg ccaaatcagt acactcactt atcaggtctg 750

 ctggatatct tcaaatcaaa gattggatgt cctttaactc cattgcctcc 800

 agttagtatt gctattcgat ttacctatgt acttcaagat tggcagcagt 850

 atttttggcc tcagcaacct ccagacatag atgcccttgt aggaggagaa 900

 gttggaggct tggagtttgg caagttacca tttggtgcct gcgaagatcc 950

 tattagtgaa ctccatttag ctactacatg gcctcatctg accgaaggga 1000

 tcattgtgga taatgatgtt tattctgatt tggatcctat tcaagctcca 1050

 cattggtctg ttagagttcg aaaagctgag aatcctcagt gtttgctagg 1100

 tgattttgtc actgaatttt ttaaaatttg ccgtcgaaag gagtcaactg 1150

 atgagattct tggacgatct gcatttgagg aagaaggcaa agaaactgct 1200

 gatataactc atgctttgtc aaaattgaca gagccggcat cagttccaat 1250

 tcataaatta tcagtttcaa atatggtaca cactgcaaag aagaaaatcc 1300

 gaaaacacag aggtgtagag gagtcaccgc taaataatga tgttcttaat 1350

 actattctcc tgttcttatt ccctgatgct gtttctgaga aaccattaga 1400

 tggaactact tcaacagata ataataatcc tccatcagag agtgaagact 1450

 ataatctcta caatcagttc aagtctgcac catctgacag tttaacatac 1500

 aaactggctt tgtgtctctg tatgatcaat ttttaccatg gagggttgaa 1550

 aggagtggca cacctctggc aggaatttgt tcttgaaatg cgtttccgat 1600

 gggaaaacaa ctttctgatt ccaggattag caagtggacc cccagatctg 1650

 aggtgttgtt tactgcatca gaaactacag atgttaaatt gttgtattga 1700

 aagaaagaag gcacgtgatg aggggaaaaa gacaagtgct tcagatgtca 1750

 ctaatatata tccaggggat gctggaaaag caggagacca gttggtgcca 1800

 gataatctaa aagaaacaga taaggaaaag ggagaggtag gaaaatcttg 1850

 ggattcctgg agtgacagcg aagaagaatt ttttgaatgc ctaagtgata 1900

 ctgaagaact taaaggaaat ggacaagaga gtggcaagaa aggaggacct 1950

 aaggagatgg caaatttaag gccggaagga cggctctatc agcatgggaa 2000

 acttacactg ctgcataatg gagaacctct ctacattcca gtaacccagg 2050

 aaccagcacc tatgacagaa gatctgctag aagagcagtc tgaagtttta 2100

 gctaaattag gtacatcggc agagggggct caccttcgag cacgcatgca 2150

 gagtgcctgt ctgctctcag atatggagtc ttttaaggca gctaatccag 2200

 gttgctccct ggaagatttt gtgaggtggt attcaccccg ggattatatt 2250

 gaagaggagg tgattgatga aaagggcaat gtggtgctga aaggagaact 2300

 gagtgcccgg atgaagattc caagcaatat gtgggtagaa gcctgggaaa 2350

 cagctaagcc aattcctgct agaaggcaaa ggagactctt tgatgataca 2400

 cgggaagcag aaaaggtgct gcactatctg gcaatccaga aacctgcaga 2450

 ccttgctcgg cacctgttac cttgtgtgat tcatgcagct gtactcaagg 2500

 taaaggaaga agaaagtctc gaaaacattt cttcagttaa gaagatcata 2550

 aagcagataa tatcccattc cagtaaagtt ttgcacttcc ccaatccaga 2600

 agacaagaaa ttggaagaaa tcattcacca gattactaat gtggaagctc 2650

 tcattgccag agctcggtca ctaaaagcca agtttggaac tgagaaatgt 2700

 gaacaggagg aggaaaagga agatcttgaa aggtttgtga gttgcctgct 2750

 ggagcagcct gaagtgttag tcaccggtgc aggaagagga catgctggca 2800

 ggatcattca caagctgttt gtgaatgccc agagggctgc agctatgact 2850

 ccaccagagg aggaattgaa gagaatgggc tccccagagg aaagaaggca 2900

 gaactccgtg tcagacttcc caccccctgc tggccgggaa ttcattttgc 2950

 gcaccactgt gccgcgccct gctccctact ccaaagctct gcctcagcgg 3000

 atgtacagtg ttctcaccaa agaggacttt agacttgcag gtgccttttc 3050

 atcagatact tccttcttct gattcttcta gcattactcg ttggtggctt 3100

 cagagacagt gctgcctcct cctgagggag ggaaggtacc agggagaacc 3150

 tgggaggtcc tggagagggc cctgtccagt tgggtgatca ggaatcaaac 3200

 cagcatcgga aagacttccc agcaccaagc ttgagctgtg tcgtttcgtg 3250

 gagggggcag cgaggatggg cttgagctgt tgagagattt ctgccctaga 3300

 gatggccttt gtatatgggg gggtggtggg gggacacaaa cacatcagac 3350

 actccgtcct cacactggca ggacggtgtt catcgcattc tcttctgtga 3400

 ccagcctcta ggctagcggc tgcattcgtg gtctgtgcaa acacttcgtg 3450

 gttctatata tcagcagcaa gtgtgcaaaa taaaggacct gttaactcag 3500

 atttctggat attttggtgg tagcttctag tcccagaatc tgtgttttta 3550

 aaatactaca tgacattctg tctattcaat cacctggtgg tcatctttct 3600

 tgtactaatt aactgttgat gagcattttg gatattctag gagaaagcct 3650

 ataatttcac atagtttctc tttttcatgt aactgtaacc taaatgtatt 3700

 acttctgata aaactatata tcaaatgtca ctgcaaatta gttttatatc 3750

 tgtcatgtga gatttgtctt acttattttt cttttggttg ccatggaagt 3800

 tatggccctg aaaatcgtct ccctcccctt ctcttgctgt acagcatgcg 3850

 ttctcttttt gtggttgctg gctgggtact gtatttaatg aagtagagaa 3900

 tagcacttgc aaaaatacag tcttggtacc tagagactgt catgcagata 3950

 gtataatttg gtatatgtgc taatgcattg agtagaggat tattttaaca 4000

 cactattttg cttttgtatt ttagttaaaa taatcgatgg ggatgtgtag 4050

 cccccccgtg tgaggatgac atcaccacat ttctagtttc atggagctca 4100

 agatgtcttg tgtctgtgtg gctagatggc ctctgcttgg taatcttatt 4150

 tttaggccta aaattcccac ttaaatccaa agtaaaaatg gttatactga 4200

 agcataaacc ttgcctgtgt aattttaaaa aattaataga gctgtgcaaa 4250

 ccctgttatt tttgtaaaaa aaaaaaaaaa tacatatcta tatataatat 4300

 gtgtgtgtgt gtgacatatg cacacgtctc tgtgtatgtg aagtagggga 4350

 ggccctgggg gatgacctcc cagcctttat gatgcttttc tctatgctgc 4400

 tggacttcat tcttactggt ccacgcagat gcaggcggcc tgaggccagt 4450

 gctgtaccaa gtagaagacg gttcctaagg acagagtttg tctgttttct 4500

 aacaaagaaa aattctacaa aggagaggtt gggcgttaca aaggcattgt 4550

 gaatctaata aaaggaaagt gtcgctttct ggggcgtttt ctttcatttt 4600

 ctcccgctga ggcatttcag tctaatttca tgtggtttag tgctgtctca 4650

 gctctaatgt ttgcagcctg ttgagcctaa caaggcaggg gtctccagaa 4700

 catt 4704

<210> 2805
<211> 875
<212> PRT
<213> Homo sapien

<400> 2805
 Met Asn Asn Asp Phe Pro Pro Arg Ala His Cys Leu Val Arg Trp
   1               5                  10                  15

 Tyr Gly Leu Arg Glu Phe Met Val Ile Ala Pro Ala Ala His Ser
                  20                  25                  30

 Asp Ala Val Leu Ser Glu Ser Lys Cys Asn Leu Leu Leu Ser Ser
                  35                  40                  45

 Val Ser Ile Ala Leu Gly Asn Thr Gly Cys Gln Val Pro Leu Phe
                  50                  55                  60

 Val Gln Ile His His Lys Trp Arg Arg Met Tyr Val Gly Glu Cys
                  65                  70                  75

 Gln Gly Pro Gly Val Arg Thr Asp Phe Glu Met Val His Leu Arg
                  80                  85                  90

 Lys Val Pro Asn Gln Tyr Thr His Leu Ser Gly Leu Leu Asp Ile
                  95                 100                 105

 Phe Lys Ser Lys Ile Gly Cys Pro Leu Thr Pro Leu Pro Pro Val
                 110                 115                 120

 Ser Ile Ala Ile Arg Phe Thr Tyr Val Leu Gln Asp Trp Gln Gln
                 125                 130                 135

 Tyr Phe Trp Pro Gln Gln Pro Pro Asp Ile Asp Ala Leu Val Gly
                 140                 145                 150

 Gly Glu Val Gly Gly Leu Glu Phe Gly Lys Leu Pro Phe Gly Ala
                 155                 160                 165

 Cys Glu Asp Pro Ile Ser Glu Leu His Leu Ala Thr Thr Trp Pro
                 170                 175                 180

 His Leu Thr Glu Gly Ile Ile Val Asp Asn Asp Val Tyr Ser Asp
                 185                 190                 195

 Leu Asp Pro Ile Gln Ala Pro His Trp Ser Val Arg Val Arg Lys
                 200                 205                 210

 Ala Glu Asn Pro Gln Cys Leu Leu Gly Asp Phe Val Thr Glu Phe
                 215                 220                 225

 Phe Lys Ile Cys Arg Arg Lys Glu Ser Thr Asp Glu Ile Leu Gly
                 230                 235                 240

 Arg Ser Ala Phe Glu Glu Glu Gly Lys Glu Thr Ala Asp Ile Thr
                 245                 250                 255

 His Ala Leu Ser Lys Leu Thr Glu Pro Ala Ser Val Pro Ile His
                 260                 265                 270

 Lys Leu Ser Val Ser Asn Met Val His Thr Ala Lys Lys Lys Ile
                 275                 280                 285

 Arg Lys His Arg Gly Val Glu Glu Ser Pro Leu Asn Asn Asp Val
                 290                 295                 300

 Leu Asn Thr Ile Leu Leu Phe Leu Phe Pro Asp Ala Val Ser Glu
                 305                 310                 315

 Lys Pro Leu Asp Gly Thr Thr Ser Thr Asp Asn Asn Asn Pro Pro
                 320                 325                 330

 Ser Glu Ser Glu Asp Tyr Asn Leu Tyr Asn Gln Phe Lys Ser Ala
                 335                 340                 345

 Pro Ser Asp Ser Leu Thr Tyr Lys Leu Ala Leu Cys Leu Cys Met
                 350                 355                 360

 Ile Asn Phe Tyr His Gly Gly Leu Lys Gly Val Ala His Leu Trp
                 365                 370                 375

 Gln Glu Phe Val Leu Glu Met Arg Phe Arg Trp Glu Asn Asn Phe
                 380                 385                 390

 Leu Ile Pro Gly Leu Ala Ser Gly Pro Pro Asp Leu Arg Cys Cys
                 395                 400                 405

 Leu Leu His Gln Lys Leu Gln Met Leu Asn Cys Cys Ile Glu Arg
                 410                 415                 420

 Lys Lys Ala Arg Asp Glu Gly Lys Lys Thr Ser Ala Ser Asp Val
                 425                 430                 435

 Thr Asn Ile Tyr Pro Gly Asp Ala Gly Lys Ala Gly Asp Gln Leu
                 440                 445                 450

 Val Pro Asp Asn Leu Lys Glu Thr Asp Lys Glu Lys Gly Glu Val
                 455                 460                 465

 Gly Lys Ser Trp Asp Ser Trp Ser Asp Ser Glu Glu Glu Phe Phe
                 470                 475                 480

 Glu Cys Leu Ser Asp Thr Glu Glu Leu Lys Gly Asn Gly Gln Glu
                 485                 490                 495

 Ser Gly Lys Lys Gly Gly Pro Lys Glu Met Ala Asn Leu Arg Pro
                 500                 505                 510

 Glu Gly Arg Leu Tyr Gln His Gly Lys Leu Thr Leu Leu His Asn
                 515                 520                 525

 Gly Glu Pro Leu Tyr Ile Pro Val Thr Gln Glu Pro Ala Pro Met
                 530                 535                 540

 Thr Glu Asp Leu Leu Glu Glu Gln Ser Glu Val Leu Ala Lys Leu
                 545                 550                 555

 Gly Thr Ser Ala Glu Gly Ala His Leu Arg Ala Arg Met Gln Ser
                 560                 565                 570

 Ala Cys Leu Leu Ser Asp Met Glu Ser Phe Lys Ala Ala Asn Pro
                 575                 580                 585

 Gly Cys Ser Leu Glu Asp Phe Val Arg Trp Tyr Ser Pro Arg Asp
                 590                 595                 600

 Tyr Ile Glu Glu Glu Val Ile Asp Glu Lys Gly Asn Val Val Leu
                 605                 610                 615

 Lys Gly Glu Leu Ser Ala Arg Met Lys Ile Pro Ser Asn Met Trp
                 620                 625                 630

 Val Glu Ala Trp Glu Thr Ala Lys Pro Ile Pro Ala Arg Arg Gln
                 635                 640                 645

 Arg Arg Leu Phe Asp Asp Thr Arg Glu Ala Glu Lys Val Leu His
                 650                 655                 660

 Tyr Leu Ala Ile Gln Lys Pro Ala Asp Leu Ala Arg His Leu Leu
                 665                 670                 675

 Pro Cys Val Ile His Ala Ala Val Leu Lys Val Lys Glu Glu Glu
                 680                 685                 690

 Ser Leu Glu Asn Ile Ser Ser Val Lys Lys Ile Ile Lys Gln Ile
                 695                 700                 705

 Ile Ser His Ser Ser Lys Val Leu His Phe Pro Asn Pro Glu Asp
                 710                 715                 720

 Lys Lys Leu Glu Glu Ile Ile His Gln Ile Thr Asn Val Glu Ala
                 725                 730                 735

 Leu Ile Ala Arg Ala Arg Ser Leu Lys Ala Lys Phe Gly Thr Glu
                 740                 745                 750

 Lys Cys Glu Gln Glu Glu Glu Lys Glu Asp Leu Glu Arg Phe Val
                 755                 760                 765

 Ser Cys Leu Leu Glu Gln Pro Glu Val Leu Val Thr Gly Ala Gly
                 770                 775                 780

 Arg Gly His Ala Gly Arg Ile Ile His Lys Leu Phe Val Asn Ala
                 785                 790                 795

 Gln Arg Ala Ala Ala Met Thr Pro Pro Glu Glu Glu Leu Lys Arg
                 800                 805                 810

 Met Gly Ser Pro Glu Glu Arg Arg Gln Asn Ser Val Ser Asp Phe
                 815                 820                 825

 Pro Pro Pro Ala Gly Arg Glu Phe Ile Leu Arg Thr Thr Val Pro
                 830                 835                 840

 Arg Pro Ala Pro Tyr Ser Lys Ala Leu Pro Gln Arg Met Tyr Ser
                 845                 850                 855

 Val Leu Thr Lys Glu Asp Phe Arg Leu Ala Gly Ala Phe Ser Ser
                 860                 865                 870

 Asp Thr Ser Phe Phe
                 875

<210> 2806
<211> 2760
<212> DNA
<213> Homo sapien

<400> 2806
 ttcatattaa aaaaatagct ggtaaatctt tctaggtagt aacttatcca 50

 aacaatactt tgagtatcat attttgtgaa tgacttgctt aaactgggaa 100

 actgaatatt ctttttaaat catataattc ctgtattaaa tgtgaaacac 150

 acagtctcca aagtcacctg attctctgtg gaaaatgaaa ggcattgaag 200

 gaaaccagat acattaatac ttagttttgg ttgaaagtgc aacattactg 250

 tacttagaag gggcttggtt tatttttaga tatttaagct atcattaatt 300

 ttagaccaat ggctaataat aagagagatt tttggttgct catttatgga 350

 gagacaaaga acagcatggc ataaacaaac atcccagaaa taaatgaaaa 400

 gttttaagtg ataaaattgt gttttctatg aaccagtgtt gtacatgaac 450

 caacattgtg tttcttagct ctgacctgta cagtgaggta cctgtcagga 500

 cccctagtct tggcactgga aatgacaaag ttctcctatt actaaattct 550

 catgccttcc ttttctgact tagtagattg aaattggtag gtactaatga 600

 tttatgtttg ataaacttaa gttctgctga tatcctgtta ctggtaattc 650

 tggtaccaaa atttcaaacg gtttgattat tagtagcatt ttgagtacct 700

 aggtgcatat aatacagtta gcagaccctt acagagtcaa aagagatttt 750

 ggaatctggt gatactgttg tttattacac tagcctatta cattttcttt 800

 ctttataata actgtttatg tgagtttcat tgaaaatcgt ggctctattg 850

 ctttattcat ggtttccaca actctttttg taacacctta attttctctc 900

 ttaggtattt tcctgttaaa taagatatca aaagcatcaa tcacaagaca 950

 gagaaaacgt attaggaaaa acttgtatta gtatattcta aactgaaatg 1000

 gaaaaactca ttattcatat tttaataaat aaaactccca aatgatcttg 1050

 ctaaattatc ccactattta gaagtagaaa ataagagaag agtgctttca 1100

 aggaaatttg tcatattctc ccttctatct agaagttgac aatgaattgc 1150

 aataaaacta agaaataact gaatgctgaa aaataccatg aattaatgtt 1200

 atggcttctt tatttttgta tatccattcc cacaaaattg aatttaagat 1250

 tattaatgaa aattctatat taagtaataa tgcttgtatt agtaatgggc 1300

 aaagaagtct ttctttgtta cattaaccgt tagtaaaaga tgtactttga 1350

 catttctgat gtaaaaccta tatgtaaata ttgtaattta aatatgattg 1400

 gacagctgtt aagttttggg gagggaagca gatgccagcg ttctctgctg 1450

 aaaagacaag atggcgcttg acggaccaca gcagatggag ctggaggagg 1500

 aaaaggcagg cagtggactc tgccagtatt atctgtccaa gattgaagaa 1550

 ctccagggtc aactgcaata taaattggat gggggaaagc cacaaggaac 1600

 agttctgaac tccaggtgca tttgcagctg attttgaatg ataagaccca 1650

 aaacctctgg aggcggcagg tgcacgggaa tgaactaaat gttaaagtgt 1700

 gcctattaca ggaggagcta cagctgctgc aggaatagga ctcctgtgtc 1750

 agggaagtag tccaggccat gggtaagaag aaagtgttgg tcaaggtgca 1800

 tctcaaggac aagtttgtca tagatgtgga caaaaatatc agcatcagtg 1850

 atgtgacacc cagttccttg gtggttctaa gaaatgacag ctacactttg 1900

 cacaagatcc tacccaacaa ggtggactca ttggtgtcac tgatgatggt 1950

 gaagaaagta ccagattcag cttatgaaat gattggtaga ctggataggc 2000

 agatcaagaa gatcaaagaa gtgatcgacc tgcctgctaa gcatcccgag 2050

 ctcttcaaag cactgggcat tgcacagccc aagggaatgc tgcttggaag 2100

 agactgttgg cctgggctct ggctcatcat agggactgtg tacctttatt 2150

 catgtctctg gctctgaatt ggtacagaaa ttcattgggg aatttctgtg 2200

 atggcagaga aaatgctcat ctgtcatctt catggatgaa attgactctt 2250

 ttggctcctc agagctggag ggggatgctg gagggaacag tgaagtgcag 2300

 cagatgatgc ttcgagggtg gctttgaggc caccaagagt atcacggttt 2350

 atcacggctg ctaatacgat tgatatcctg gactcggcac tgctttgccc 2400

 agggcacatt gacagaaaaa ttgaattccc aacctgcaat gagtaggcct 2450

 ggctggtcac tttgaagatt cattctcaga aatgaacctg acccagggga 2500

 tcaacctgag aaaaattgct gagcttatgc caggagcatc aggctgaagt 2550

 gaagggcatg tgcacagaaa ccggcatgta tgccctgagt agcgagtcca 2600

 tgtcactcag aaggactttg aggtagtcca aagtcctatc tcatgccaaa 2650

 ggacagtgag gaaaaacatg tccatcaaga aactatggaa ttgagggcac 2700

 atcctttgtg tgtatcccta caataaaact cagtgggaca agcaaaaaaa 2750

 aaaaaaaaaa 2760

<210> 2807
<211> 132
<212> PRT
<213> Homo sapien

<400> 2807
 Met Gly Lys Lys Lys Val Leu Val Lys Val His Leu Lys Asp Lys
   1               5                  10                  15

 Phe Val Ile Asp Val Asp Lys Asn Ile Ser Ile Ser Asp Val Thr
                  20                  25                  30

 Pro Ser Ser Leu Val Val Leu Arg Asn Asp Ser Tyr Thr Leu His
                  35                  40                  45

 Lys Ile Leu Pro Asn Lys Val Asp Ser Leu Val Ser Leu Met Met
                  50                  55                  60

 Val Lys Lys Val Pro Asp Ser Ala Tyr Glu Met Ile Gly Arg Leu
                  65                  70                  75

 Asp Arg Gln Ile Lys Lys Ile Lys Glu Val Ile Asp Leu Pro Ala
                  80                  85                  90

 Lys His Pro Glu Leu Phe Lys Ala Leu Gly Ile Ala Gln Pro Lys
                  95                 100                 105

 Gly Met Leu Leu Gly Arg Asp Cys Trp Pro Gly Leu Trp Leu Ile
                 110                 115                 120

 Ile Gly Thr Val Tyr Leu Tyr Ser Cys Leu Trp Leu
                 125                 130

<210> 2808
<211> 2066
<212> DNA
<213> Homo sapien

<400> 2808
 tcttgccttc cggcccggcg cccgatttcc gccttccgac ccagctgtgg 50

 gctgcgcccc acgccagccc gcgccccgca tggctgccgc cggggccagg 100

 cctgtggagc tgggcttcgc cgagtcggcg ccggcgtggc gactgcgcag 150

 cgagcagttc cccagcaagg tgggcgggcg gccggcatgg ctgggcgcgg 200

 ccgggctgcc ggggccccag gccctggcct gcgagctgtg cggccgcccg 250

 ctctccttcc tgctgcaggt gtatgcgccg ctgcctggcc gcccggacgc 300

 cttccaccgc tgcatcttcc tcttctgctg ccgcgagcag ccgtgctgtg 350

 ccggcctgcg agtttttagg aatcaactac ccaggaaaaa cgatttttac 400

 tcatatgagc caccttctga gaatcctccc ccagaaacag gagaatcagt 450

 gtgtctccag cttaagtctg gtgctcatct ctgcagggtt tgtggctgtt 500

 taggccccaa aacgtgctcc agatgccaca aagcatatta ctgcagcaag 550

 gagcatcaga ccctagactg gagattggga cataagcagg cttgtgcaca 600

 accagatcat ctggaccata taattccaga ccacaacttc ctttttccag 650

 aatttgaaat tgtaatagaa acagaagatg agattatgcc tgaggttgtg 700

 gaaaaggaag attactcaga gattataggg agcatgggta agcagtttca 750

 ggacttcatt cattaagtgg ttaaacataa tacttggaag aaagggctcc 800

 atgtgcctag aagagaggta ctgagaggaa gactcacttt ggaggctgta 850

 gcatacaatt ttcagatatt gcctcaggta aaaatatact tcctggactt 900

 tgttttctga cacataagag gtgtgttctg ctccctgtaa agacaagggt 950

 gggtatccag atggtcccat gagtagggct gcacaagatg ctggaggctt 1000

 ggtaagttcc tctgggtcgc agatcggttt ctcgggtcgg gatagtgtga 1050

 gtgcctagca cagtgtcggg cacgcagaag ggccccttaa aagtttctct 1100

 ttcatctggc cagttttaga tacacaattt tgtcagttta cttacagtgc 1150

 atactcttgg gtagtacttg tgctgaccaa gtatcttaga ggcttatttt 1200

 attatagtag ccaacattta tccagcactt accttatata aagggctgtt 1250

 tgtgcatgag ctcattaaaa tcgtgacagc agaccaatga gtgagaaact 1300

 gccccatttt gaaggtgagg aaattgaggt tctgggtata actttctttg 1350

 gtcacataat attaaatttt acaatttgag ccttgagcca tacacaaaac 1400

 caccacaaaa ttagatttat agactcaaaa tgaaaacatc agcttactgg 1450

 tttgtagttc ataccagtca tacattccaa aacatgtttt gagtcttact 1500

 ctgtgcctga ccttgtgctt gataacaggg atataatggg aagcaacact 1550

 ccagtggtca gatgctcaca gtcttatgga ggagcccaaa taatatctgg 1600

 ggaagttaaa gtccatataa tgactgataa gagtacaata caggtgccat 1650

 gggaacacgt gacatcactg aagactgcct ggaaggggcc gcgcgtgtgt 1700

 tcatgcctat acgataaaca tgatacataa tgaaaatgct tatctttagg 1750

 agaaaggaga gcctagagta gcaggatcaa ggatgaaagc tggacttcaa 1800

 atatgccttg ttagtgtaaa tgtgactgtg gaactgtatg agtattttaa 1850

 gattatggag taaagtaagt tttaaaaagc agtccctaat catcaaaagt 1900

 aaaaaactct tgatgtagtc atataaccac actaagaact cttccaggtg 1950

 acttcaaaac ataggacagt acatctctag tagaatatgc cctgagaatg 2000

 aaaagaatgt aacagtgtta gtattttgaa taaacatgtt attactaaaa 2050

 aaaaaaaaaa aaaaaa 2066

<210> 2809
<211> 228
<212> PRT
<213> Homo sapien

<400> 2809
 Met Ala Ala Ala Gly Ala Arg Pro Val Glu Leu Gly Phe Ala Glu
   1               5                  10                  15

 Ser Ala Pro Ala Trp Arg Leu Arg Ser Glu Gln Phe Pro Ser Lys
                  20                  25                  30

 Val Gly Gly Arg Pro Ala Trp Leu Gly Ala Ala Gly Leu Pro Gly
                  35                  40                  45

 Pro Gln Ala Leu Ala Cys Glu Leu Cys Gly Arg Pro Leu Ser Phe
                  50                  55                  60

 Leu Leu Gln Val Tyr Ala Pro Leu Pro Gly Arg Pro Asp Ala Phe
                  65                  70                  75

 His Arg Cys Ile Phe Leu Phe Cys Cys Arg Glu Gln Pro Cys Cys
                  80                  85                  90

 Ala Gly Leu Arg Val Phe Arg Asn Gln Leu Pro Arg Lys Asn Asp
                  95                 100                 105

 Phe Tyr Ser Tyr Glu Pro Pro Ser Glu Asn Pro Pro Pro Glu Thr
                 110                 115                 120

 Gly Glu Ser Val Cys Leu Gln Leu Lys Ser Gly Ala His Leu Cys
                 125                 130                 135

 Arg Val Cys Gly Cys Leu Gly Pro Lys Thr Cys Ser Arg Cys His
                 140                 145                 150

 Lys Ala Tyr Tyr Cys Ser Lys Glu His Gln Thr Leu Asp Trp Arg
                 155                 160                 165

 Leu Gly His Lys Gln Ala Cys Ala Gln Pro Asp His Leu Asp His
                 170                 175                 180

 Ile Ile Pro Asp His Asn Phe Leu Phe Pro Glu Phe Glu Ile Val
                 185                 190                 195

 Ile Glu Thr Glu Asp Glu Ile Met Pro Glu Val Val Glu Lys Glu
                 200                 205                 210

 Asp Tyr Ser Glu Ile Ile Gly Ser Met Gly Lys Gln Phe Gln Asp
                 215                 220                 225

 Phe Ile His


<210> 2810
<211> 1442
<212> DNA
<213> Homo sapien

<400> 2810
 ggccccagct gaagaatgag accatctggt acgtgcgctt cctgtgggag 50

 tgacccgccg cccccgaccc aggtgcccag ctctcggaat gactgtggct 100

 ccactgtccc tgacaacccc ttcgtccgga ccctccccca cacaactatg 150

 tctggtcacc agctccctcc tgctggcacc cagagacccg gacccgcagg 200

 gcctgcctgg ttcctggaag tcttcccagt cttcccagcc agcccgggcc 250

 ctggggagcc ctgggcacag cagcggccga ggggatgtcc tgctccaata 300

 cccgcactgc tctggagttt gccctctttc ccaaggagat gctgctgggg 350

 agctggtatg ggtggggtct ttccctttac agacggggca gatgccagga 400

 ctcagcccat cctgaggagg acacgtgtcc tcatggagag ggtgctccgg 450

 cccaggcggg ggagtcggtg cccagtcagc agctctgcca ccatcctgct 500

 gggaactggg ggggcctcta ttgggttata ggcaaggcct tttctctggc 550

 atggaattgt taattttctg acacgtctag atgtgaaatt tctgaaaatg 600

 ttgaagcaga gaaacattca cacacaaaaa gcaacatagt catgtgggtc 650

 cagatggcct cagtcctaga tgttggcacc ctttgctgtg tctcctcaga 700

 gtatcctgtt ccgcctcctg ccacctggac ctccctcagt ggatgtcttc 750

 cctcccccga ccccagcctg tcagtccgag cacagtgcag gtttggctct 800

 gacttgggcc tttggctgca gtgggggtgg atttcagagc ctctcatggc 850

 agcatctaag tgaccagagc tgggatgaga gaggggaagg ggcaatgtga 900

 gtggcgctat gggacgggcc agccctgctc ctgagccagc cccgccctct 950

 gccccctggc cctgggctct gtgctaggga tggtgaagaa tgggggcgtg 1000

 ccagcctggc aggagtggga agcaacacgc aggggtcccg gacctctcca 1050

 gccttgccct cacgcttatc cgagctccca gtgtggttag cacagagctc 1100

 acccaccttg cctggctccc agctggggcc tgtcctcact ggtgctccag 1150

 gggaagaaac gacagcctca cttctgtatg gactgctgat gtggcctgcc 1200

 atcctgttca gcgggcattg tctttggagc agcaggagac taggatgcct 1250

 ctcactcaca tgccagttcc tggctggcca gctgctcagg gctcaggctg 1300

 gggcctccca ttgacatcct ccccctacac tccctctttg agcctccgtc 1350

 gcccctcctg ttgggtaagg gtgttgagtg tgacttgtgc tgaaaacctg 1400

 gttcatatat aataaataat ggtgatgaaa aaaaaaaaaa aa 1442

<210> 2811
<211> 92
<212> PRT
<213> Homo sapien

<400> 2811
 Met Ser Cys Ser Asn Thr Arg Thr Ala Leu Glu Phe Ala Leu Phe
   1               5                  10                  15

 Pro Lys Glu Met Leu Leu Gly Ser Trp Tyr Gly Trp Gly Leu Ser
                  20                  25                  30

 Leu Tyr Arg Arg Gly Arg Cys Gln Asp Ser Ala His Pro Glu Glu
                  35                  40                  45

 Asp Thr Cys Pro His Gly Glu Gly Ala Pro Ala Gln Ala Gly Glu
                  50                  55                  60

 Ser Val Pro Ser Gln Gln Leu Cys His His Pro Ala Gly Asn Trp
                  65                  70                  75

 Gly Gly Leu Tyr Trp Val Ile Gly Lys Ala Phe Ser Leu Ala Trp
                  80                  85                  90

 Asn Cys


<210> 2812
<211> 1921
<212> DNA
<213> Homo sapien

<400> 2812
 ggcacgaggg ggcggccgac gacgttcgtc atttagtgcg ggagggatcc 50

 tgaaccgcgc ggccgaaccc tccggtgtcc cgacccaggc taagcttgag 100

 catggctgag caggagccca cagccgagca gctggcccag attgcagcgg 150

 agaacgagga ggatgagcac tcggtcaact acaagccccc ggcccagaag 200

 agcatccagg agatccagga gctggacaag gacgacgaga gcctgcgaaa 250

 gtacaaggag gccctgctgg gccgcgtggc cgtttccgca gaccccaacg 300

 tccccaacgt cgtggtgact ggcctgaccc tggtgtgcag ctcggccccg 350

 ggccccctgg agctggacct gacgggcgac ctggagagct tcaagaagca 400

 gtcgtttgtg ctgaaggagg gtgtggagta ccggataaaa atctctttcc 450

 gggttaaccg agagatagtg tccggcatga agtacatcca gcatacgtac 500

 aggaaaggcg tcaagattga caagactgac tacatggtag gcagctatgg 550

 gccccgggcc gaggagtacg agttcctgac ccccgtggag gaggcaccca 600

 agggtatgct ggcccggggc agctacagca tcaagtcccg cttcacagac 650

 gacgacaaga ccgaccacct gtcctgggag tggaatctca ccatcaagaa 700

 ggactggaag gactgagccc agccagaggc gggcagggca gactgacgga 750

 cggacgacgg acaggcggat gtgtcccccc cagcccctcc cctccccata 800

 ccaaagtgct gacaggccct ccgtgcccct cccaccctgg tccgcctccc 850

 tggcctggct caaccgagtg cctccgaccc ccctcctcag ccctccccca 900

 cccacaggcc cagcctcctc ggtctcctgt ctcgttgctg cttctgcctg 950

 tgctgtgggg gagagaggcc gcagccaggc ctctgctgcc ctttctgtgc 1000

 cccccaggtt ctatctcccc gtcacacccg aggcctggct tcaggaggga 1050

 gcggagcagc cattctccag gccccgtggt tgcccctgga cgtgtgcgtc 1100

 tgctgctccg gggtggagct ggggtgtggg atgcacggcc tcgtgggggc 1150

 cgggccgtcc tccagccccg ctgctccctg gccagccccc ttgtcgctgt 1200

 cggtcccgtc taaccatgat gccttaacat gtggagtgta ccgtggggcc 1250

 tcactagcct ctaactccct gtgtctgcat gagcatgtgg cctccccgtc 1300

 ccttccccgg tggcgaaccc agtgacccag ggacacgtgg ggtgtgctgc 1350

 tgctgctccc cagcccacca gtgcctggcc agcctgcccc cttccctgga 1400

 cagggctgtg gagatggctc cggcggcttg gggaaagcca aattgccaaa 1450

 actcaagtca cctcagtacc atccaggagg ctgggtattg tcctgcctct 1500

 gccttttctg tctcagcggg cagtgcccag agcccacacc cccccaagag 1550

 ccctcgatgg acagcctcac ccaccccacc tgggcccagc caggagcccc 1600

 gcctggccat cagtatttat tgcctccgtc cgtgccgtcc ctgggccact 1650

 ggcctggcgc ctgttccccc aggctctcag tgccaccacc cccggcaggc 1700

 cttccctgac ccagccagga acaaacaagg gaccaagtgc acacattgct 1750

 gagagccgtc tcctgtgcct cccccgcccc atccccggtc ttcgtgttgt 1800

 gtctgccagg ctcaggcaga ggcgcctgtc cctgcttctt ttctgaccgg 1850

 gaaataaatg cccctgaagg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaaaaaa a 1921

<210> 2813
<211> 204
<212> PRT
<213> Homo sapien

<400> 2813
 Met Ala Glu Gln Glu Pro Thr Ala Glu Gln Leu Ala Gln Ile Ala
   1               5                  10                  15

 Ala Glu Asn Glu Glu Asp Glu His Ser Val Asn Tyr Lys Pro Pro
                  20                  25                  30

 Ala Gln Lys Ser Ile Gln Glu Ile Gln Glu Leu Asp Lys Asp Asp
                  35                  40                  45

 Glu Ser Leu Arg Lys Tyr Lys Glu Ala Leu Leu Gly Arg Val Ala
                  50                  55                  60

 Val Ser Ala Asp Pro Asn Val Pro Asn Val Val Val Thr Gly Leu
                  65                  70                  75

 Thr Leu Val Cys Ser Ser Ala Pro Gly Pro Leu Glu Leu Asp Leu
                  80                  85                  90

 Thr Gly Asp Leu Glu Ser Phe Lys Lys Gln Ser Phe Val Leu Lys
                  95                 100                 105

 Glu Gly Val Glu Tyr Arg Ile Lys Ile Ser Phe Arg Val Asn Arg
                 110                 115                 120

 Glu Ile Val Ser Gly Met Lys Tyr Ile Gln His Thr Tyr Arg Lys
                 125                 130                 135

 Gly Val Lys Ile Asp Lys Thr Asp Tyr Met Val Gly Ser Tyr Gly
                 140                 145                 150

 Pro Arg Ala Glu Glu Tyr Glu Phe Leu Thr Pro Val Glu Glu Ala
                 155                 160                 165

 Pro Lys Gly Met Leu Ala Arg Gly Ser Tyr Ser Ile Lys Ser Arg
                 170                 175                 180

 Phe Thr Asp Asp Asp Lys Thr Asp His Leu Ser Trp Glu Trp Asn
                 185                 190                 195

 Leu Thr Ile Lys Lys Asp Trp Lys Asp
                 200

<210> 2814
<211> 7360
<212> DNA
<213> Homo sapien

<400> 2814
 gcggccgccg ccaggcagca gaggcgactg cggacagccg gcggggaccg 50

 ggaaagagga ggcctggcgc ctccggcaga ggggcgagga ccgagcgccc 100

 aaggctggga gagacgccgg cgctgagctt cccagcgccg cctcacctcg 150

 cttttcgaac tccgcgaccc gagcgcaagg cttaagcagg taaagcagtc 200

 actgtgaaga aaataacatt ttaagaaact tttctgtcac aattgataga 250

 ggaaaagcca gtagagaagt acatcttctt gtgtgtgtgt ctcatcgtgc 300

 cactttttgt aactcagctt agtaatgaag ccaccattat gtcctcagtc 350

 agtgaagtaa atgtggatat aaaagatttc ctaatgagca ttaatttgga 400

 gcagtatctc ttacatttcc atgagtctgg ttttactact gtgaaggact 450

 gtgcagcaat aaatgacagc ctgctgcaga aaattggaat atcacctaca 500

 ggtcaccgta ggaggatact taaacagtta cagataatct tgtcaaaaat 550

 gcaagatatt ccaatatatg caaatgttca taaaactaag aagaatgatg 600

 acccttcaaa ggattaccat gttccatctt ctgatcagaa tatctgcata 650

 gaactttcca attctggtag tgttcagaca tctagcccac cgcagttgga 700

 gactgttaga aaaaatcttg aagacagtga tgcaagtgtg gaaagaagcc 750

 agtatcctca atcagatgat aagctgtctc ctcctaaacg cgacttcccc 800

 actgcagagg aaccacacct gaatttgggt tctttgaatg attctttatt 850

 tggtagtgac aatattaaaa tagaatcatt gattacaaag aagactgtgg 900

 atcacacagt tgaagaacaa caaacagaaa aagttaaatt gatcacagaa 950

 aatctcagta agctccctaa tgcagactct gaatgccttt cttttgttgg 1000

 ctgttcaaca tcaggaacaa attctggaaa tggaacaaat ggtttattag 1050

 aaggatcacc accatcccca ttctttaagt ttcaaggaga aatgattgta 1100

 aatgacttgt atgttccatc atcaccaatc ctagcacctg tgagaagtcg 1150

 tagcaagttg gtttcaagac catctcgatc ttttctgcta agacatcgac 1200

 ctgtaccaga gattccaggg tcaacaaaag gagtttctgg gagctatttc 1250

 cgtgaaagaa gaaatgttgc tacctcaact gaaaaatctg tggcatggca 1300

 aaattcaaat gaggagaatt catcttccat ctttccttat ggagagacct 1350

 ttctcttcca gagactagaa aattccaaga agcgatctat aaagaatgaa 1400

 tttttgaccc agggagaagc actcaaaggg gaagcagcta ctgcaacaaa 1450

 ctcttttatc atcaaatcaa gcatatacga taacagaaag gagaaaataa 1500

 gcgaggacaa ggtggaagat atttggatac ctcgagagga caaaaacaat 1550

 tttttgatag acactgcttc tgaatcagaa tactcaacag tagaagaatg 1600

 ctttcagagt ttaagaagaa aaaattcaaa ggcatctaaa tctaggactc 1650

 aaaaagcctt gattttggac tccgttaata ggcacagtta tccgttaagc 1700

 tcaacaagtg gaaatgctga ttcatcagcc gtttcttcac aggcaatatc 1750

 tccctatgcc tgcttttatg gagcatctgc aaagaaggtt aaatcaggat 1800

 ggctggataa actctctcct caaggaaaac gcatgtttca aaagagatgg 1850

 gtgaaatttg atggccttag catttcttac tacaataatg agaaggagat 1900

 gtattcgaaa ggaataattc ccctttctgc tatatcaaca gtacgagttc 1950

 aaggagacaa caaatttgaa gttgttacaa cacaaagaac ttttgttttt 2000

 agagtagaaa aagaagagga gagaaatgac tggatcagca tactattaaa 2050

 tgcactgaaa tcacaatccc ttacctcgca gtctcaagct gttgttacac 2100

 ctgagaaatg tggatatctt gaattgagag gctataaggc aaaaattttt 2150

 actgtgttaa gtggaaacag tgtgtggctt tgcaaaaacg aacaggattt 2200

 taagagtgga cttggtatta ccataattcc tatgaatgta gcaaatgtaa 2250

 agcaagtgga ccgaactgtg aaacaatctt ttgaaataat cactccctac 2300

 aggagtttca gctttacagc cgagactgaa aaggagaaac aagactggat 2350

 tgaagctgtg cagcaatcaa tagcagaaac tctctctgat tatgaagtag 2400

 ctgagaagat ttggttcaat gaatccaaca ggagctgtgc agattgtaaa 2450

 gccccagatc ctgactgggc atccatcaat ctctgtgttg tcatctgtaa 2500

 gaagtgtgca ggacagcata gatctttagg accaaaagat tccaaggtta 2550

 gaagtctaaa aatggatgct agcatttgga gcaatgaact catcgagctt 2600

 tttattgtca ttggaaacaa aagagcaaat gacttttggg ctggtaatct 2650

 tcaaaaggat gaagaattac atatggactc accagtagaa aagagaaaaa 2700

 actttattac tcagaaatat aaagaaggaa aattcagaaa aactcttttg 2750

 gcatctctca ccaaagaaga attaaataag gctctatgtg ctgctgtagt 2800

 gaaaccggat gttctagaaa caatggcttt gctgttcagt ggagcagatg 2850

 tcatgtgtgc caccggagac cccgtgcata gcacccccta tctgctagcc 2900

 aagaaagctg ggcaaagtct gcaaatggaa tttctctacc ataacaaatt 2950

 ctcagatttc cctcaacatg atattcattc cgagggtgta ttaagtcaag 3000

 agtcttccca gtccacattc ctctgtgact ttttatatca agctccttct 3050

 gctgcttcta aactctcttc agagaaaaaa ctgcttgaag agacaaataa 3100

 aaaatggtgt gttttggaag gaggcttctt gagttactat gaaaatgata 3150

 agtctaccac acctaatggc accattaata tcaatgaagt tatctgcctg 3200

 gctatacaca aagaggactt ctatttaaat actgggccca tctttatctt 3250

 tgagatctac ttaccctccg aacgtgtgtt tttatttgga gctgaaacat 3300

 ctcaagctca aagaaaatgg acagaggcaa tagccaagca ttttgttccc 3350

 ttatttgctg aaaacttaac agaagctgac tatgatttga ttggtcaact 3400

 cttctacaaa gactgccatg ccctggatca gtggagaaaa ggctggtttg 3450

 ctatggacaa atccagcttg catttttgcc ttcaaatgca agaagttcag 3500

 ggagatagaa tgcacttaag aagactgcaa gagctaacaa tcagcacaat 3550

 ggttcaaaat ggggaaaaac tggatgtttt actcttggta gaaaaaggga 3600

 gaacattata catccatggg cataccaagt tggatttcac agtctggcat 3650

 actgcaattg aaaaagcagc aggtacagat ggtaatgctt tacaagatca 3700

 gcagctcagc aaaaatgacg ttcccattat agtgaacagc tgtatagcat 3750

 ttgttacaca gtatggttta ggatgcaaat atatctatca aaagaatggt 3800

 gatcctttgc atataagtga actcctggag agtttcaaaa aggatgcaag 3850

 aagctttaaa ttgagggctg gaaaacatca gcttgaagat gtgacggctg 3900

 tgttgaaaag ttttctctct gacattgatg atgcactgct tactaaggag 3950

 ctctacccat attggatctc tgctttagat acgcaagatg acaaggaaag 4000

 aattaaaaaa tatggagcat ttatacgttc tcttccaggg gtcaaccgag 4050

 caacactagc agctatcatt gaacacctgt atagggttca gaaatgctca 4100

 gaaatcaatc acatgaatgc ccataatttg gccttggtct tttcatcctg 4150

 tttgtttcaa acgaagggac aaactagtga agaagtgaat gtaattgagg 4200

 acctaattaa taattatgta gaaatatttg aggttaaaga agatcaagtc 4250

 aaacaaatgg acatagaaaa tagctttatt accaagtgga aagacaccca 4300

 agtttcccag gctggagatt tgttaattga agtatatgta gaaaggaagg 4350

 aacccgactg tagtattata attcggatat ctcctgtgat ggaagcagaa 4400

 gaattaacta atgatatatt agcgataaaa aatattattc ctacaaaagg 4450

 tgatatttgg gccacatttg aagtcattga aaatgaagag ctagagcgtc 4500

 ctcttcacta caaggaaaat gtactggagc aggtgcttcg gtggagttca 4550

 ttagctgaac ctggctctgc ttacctggtg gtgaagagat tcttaaccgc 4600

 tgacacaatt aaacactgca gtgaccggag tacactggga agcatcaaag 4650

 aaggaatctt gaaaatcaaa gaagaaccat ccaaaatact atctggaaat 4700

 aagtttcaag accggtattt tgttttacga gatgggtttc tctttcttta 4750

 caaggatgtg aagagtagta aacatgacaa gatgttttct ctcagttcca 4800

 tgaagtttta tcgtggagtg aaaaagaaaa tgaagcctcc aacaagctgg 4850

 ggattgaccg catattctga gaaacatcac tggcacctgt gttgtgatag 4900

 ttcacgaact cagacggagt ggatgaccag tatctttatt gcccagcatg 4950

 aatatgatat atggccacca gctggaaagg aacgaaaacg ttcaataacc 5000

 aaaaatccca aaattggagg tttgcctctg attcctatac agcatgaggg 5050

 gaatgcaacc ttggcccgga aaaatattga gagtgcaaga gcagaacttg 5100

 aaaggctgcg gctcagtgaa aagtgtgata aagagtccgt ggactctagc 5150

 ttaaaggaga gagcttccat ggtggcccac tgcctggagc acaaggacga 5200

 taaacttcga aatcgacccc gaaaacatcg gagtttcaac tgcctggagg 5250

 acacagagcc tgaagcccca cttgggcaac caaaaggcca taaaggccta 5300

 aagacattga ggaagactga ggacaggaat agcaaagcta ctttggactc 5350

 tgatcataag ttaccatcaa gggtaattga agaacttaat gtggttctac 5400

 aacggtcaag aacccttcca aaagaattac aggatgagca gattttgaag 5450

 taggaaataa aatgaattgc tccccagatt atttttttaa tattgtatgc 5500

 aatctttatg tgtaactcca aaactgaact ataagataat tcataagaat 5550

 ttgcctattg ataggcaaat ttgtctatgc ttaggcattt aaggagcatt 5600

 taaaaatatg tatatatgtg actgaatgta agattaactt tattttggtc 5650

 tgaacaaacc ttgtaaagtt ccattgtatt aacgtgtgta agaagacatt 5700

 gggttactta ggtggtcagt ccttttaaag tagttgtctg ttaagtggta 5750

 taatttatga gcagaaatct caaactgtac tgtattgtat aaaatgctgt 5800

 gtttaaatga agcctaagaa actatctgta acatattttg cactttgaga 5850

 aaccttgtat attaaattac catatgtttt taggtttaca gaagttctac 5900

 cttagggaaa agaaagggaa gtaaattgaa aaagggggga gaatttattg 5950

 tagtggctgc ctaaaaacca ctggagtttt taaaagaagc aaggagttaa 6000

 atgtcctgca aaacaaggaa gtgagctaag attcattcta gttcactaat 6050

 gaccagaact tgtcaatgag aaaccacttg ttaagaaaaa gtccagtgtt 6100

 tatttctcaa gagtaatatt cggccaacag atgtaaataa tagcactagc 6150

 cactcttatt aatatttata gtgttagaaa accagccaca ttacagattc 6200

 actacgtttg agctcattgt tggtggctgc taagaggaaa cttacactgc 6250

 attggagagg ttgtgtacac aggacctggc ctggatgctg attgcactgt 6300

 cattgtatgc aagcattttg tcttttttca gaatttctga ctatactttt 6350

 ggtacgaaca aaattcatca ccacagggtc ctgttgtttt gtttgatttt 6400

 tagatttttt taaattatta ttaaggttgt aatgtttttc tccgagttgt 6450

 cagaaataac tggaagaata caatatatgg ccattatgga gccaggggct 6500

 agttggtggt ttactataca tttgggggct acctggtcac atttaatcta 6550

 ggtttttttt tcttttttta agtaaaggtg tggtctcttc cctgtactta 6600

 tgaataagga caaagcccta tttttgtttc cacataaaga tcagctactg 6650

 aattggtgaa tttcctgaca gacaatgcta tctaaccata gttcatgtta 6700

 ggggaagcat ttttccatca gtttctttaa aattggattg tctggtgagt 6750

 tttgatatta aacattatgt agctaagttt ttttttttta gcatttcttt 6800

 tttatttttc aatctatatt cacaggccca tacttcagtc agtccaatca 6850

 tagtacagtg atgtggtggt agatgctatg aatttcttca ttgtaaaata 6900

 cggatcattt gtattttggg gtgataaaat agttcaccat gggtatgaga 6950

 tatttattct ttaaatcaaa gtaaattaga atttttaaaa agcacaaaac 7000

 tgcaggacag tttatgaaat aggtggcact attagggaat cttcctttaa 7050

 agcaagaaat catgttattt agaaagaaaa actaatctta aacatactat 7100

 ttctaataaa tatttatatt tttatgaaat aaagaggtat gtggaaatta 7150

 atatttggtg atgttggaca gtggaaaagt atctagagtt tttacctgcc 7200

 ttatctgaat tcttcttgaa acttgagctt aaactctaat agctgtttcc 7250

 ctttctattc tgaacaactg tctccatttt tcaagtgtga gagataaggg 7300

 ctaatgatga catctcattt attttgagta aacattaaaa ttgttttaca 7350

 agtctacttg 7360

<210> 2815
<211> 1704
<212> PRT
<213> Homo sapien

<400> 2815
 Met Ser Ser Val Ser Glu Val Asn Val Asp Ile Lys Asp Phe Leu
   1               5                  10                  15

 Met Ser Ile Asn Leu Glu Gln Tyr Leu Leu His Phe His Glu Ser
                  20                  25                  30

 Gly Phe Thr Thr Val Lys Asp Cys Ala Ala Ile Asn Asp Ser Leu
                  35                  40                  45

 Leu Gln Lys Ile Gly Ile Ser Pro Thr Gly His Arg Arg Arg Ile
                  50                  55                  60

 Leu Lys Gln Leu Gln Ile Ile Leu Ser Lys Met Gln Asp Ile Pro
                  65                  70                  75

 Ile Tyr Ala Asn Val His Lys Thr Lys Lys Asn Asp Asp Pro Ser
                  80                  85                  90

 Lys Asp Tyr His Val Pro Ser Ser Asp Gln Asn Ile Cys Ile Glu
                  95                 100                 105

 Leu Ser Asn Ser Gly Ser Val Gln Thr Ser Ser Pro Pro Gln Leu
                 110                 115                 120

 Glu Thr Val Arg Lys Asn Leu Glu Asp Ser Asp Ala Ser Val Glu
                 125                 130                 135

 Arg Ser Gln Tyr Pro Gln Ser Asp Asp Lys Leu Ser Pro Pro Lys
                 140                 145                 150

 Arg Asp Phe Pro Thr Ala Glu Glu Pro His Leu Asn Leu Gly Ser
                 155                 160                 165

 Leu Asn Asp Ser Leu Phe Gly Ser Asp Asn Ile Lys Ile Glu Ser
                 170                 175                 180

 Leu Ile Thr Lys Lys Thr Val Asp His Thr Val Glu Glu Gln Gln
                 185                 190                 195

 Thr Glu Lys Val Lys Leu Ile Thr Glu Asn Leu Ser Lys Leu Pro
                 200                 205                 210

 Asn Ala Asp Ser Glu Cys Leu Ser Phe Val Gly Cys Ser Thr Ser
                 215                 220                 225

 Gly Thr Asn Ser Gly Asn Gly Thr Asn Gly Leu Leu Glu Gly Ser
                 230                 235                 240

 Pro Pro Ser Pro Phe Phe Lys Phe Gln Gly Glu Met Ile Val Asn
                 245                 250                 255

 Asp Leu Tyr Val Pro Ser Ser Pro Ile Leu Ala Pro Val Arg Ser
                 260                 265                 270

 Arg Ser Lys Leu Val Ser Arg Pro Ser Arg Ser Phe Leu Leu Arg
                 275                 280                 285

 His Arg Pro Val Pro Glu Ile Pro Gly Ser Thr Lys Gly Val Ser
                 290                 295                 300

 Gly Ser Tyr Phe Arg Glu Arg Arg Asn Val Ala Thr Ser Thr Glu
                 305                 310                 315

 Lys Ser Val Ala Trp Gln Asn Ser Asn Glu Glu Asn Ser Ser Ser
                 320                 325                 330

 Ile Phe Pro Tyr Gly Glu Thr Phe Leu Phe Gln Arg Leu Glu Asn
                 335                 340                 345

 Ser Lys Lys Arg Ser Ile Lys Asn Glu Phe Leu Thr Gln Gly Glu
                 350                 355                 360

 Ala Leu Lys Gly Glu Ala Ala Thr Ala Thr Asn Ser Phe Ile Ile
                 365                 370                 375

 Lys Ser Ser Ile Tyr Asp Asn Arg Lys Glu Lys Ile Ser Glu Asp
                 380                 385                 390

 Lys Val Glu Asp Ile Trp Ile Pro Arg Glu Asp Lys Asn Asn Phe
                 395                 400                 405

 Leu Ile Asp Thr Ala Ser Glu Ser Glu Tyr Ser Thr Val Glu Glu
                 410                 415                 420

 Cys Phe Gln Ser Leu Arg Arg Lys Asn Ser Lys Ala Ser Lys Ser
                 425                 430                 435

 Arg Thr Gln Lys Ala Leu Ile Leu Asp Ser Val Asn Arg His Ser
                 440                 445                 450

 Tyr Pro Leu Ser Ser Thr Ser Gly Asn Ala Asp Ser Ser Ala Val
                 455                 460                 465

 Ser Ser Gln Ala Ile Ser Pro Tyr Ala Cys Phe Tyr Gly Ala Ser
                 470                 475                 480

 Ala Lys Lys Val Lys Ser Gly Trp Leu Asp Lys Leu Ser Pro Gln
                 485                 490                 495

 Gly Lys Arg Met Phe Gln Lys Arg Trp Val Lys Phe Asp Gly Leu
                 500                 505                 510

 Ser Ile Ser Tyr Tyr Asn Asn Glu Lys Glu Met Tyr Ser Lys Gly
                 515                 520                 525

 Ile Ile Pro Leu Ser Ala Ile Ser Thr Val Arg Val Gln Gly Asp
                 530                 535                 540

 Asn Lys Phe Glu Val Val Thr Thr Gln Arg Thr Phe Val Phe Arg
                 545                 550                 555

 Val Glu Lys Glu Glu Glu Arg Asn Asp Trp Ile Ser Ile Leu Leu
                 560                 565                 570

 Asn Ala Leu Lys Ser Gln Ser Leu Thr Ser Gln Ser Gln Ala Val
                 575                 580                 585

 Val Thr Pro Glu Lys Cys Gly Tyr Leu Glu Leu Arg Gly Tyr Lys
                 590                 595                 600

 Ala Lys Ile Phe Thr Val Leu Ser Gly Asn Ser Val Trp Leu Cys
                 605                 610                 615

 Lys Asn Glu Gln Asp Phe Lys Ser Gly Leu Gly Ile Thr Ile Ile
                 620                 625                 630

 Pro Met Asn Val Ala Asn Val Lys Gln Val Asp Arg Thr Val Lys
                 635                 640                 645

 Gln Ser Phe Glu Ile Ile Thr Pro Tyr Arg Ser Phe Ser Phe Thr
                 650                 655                 660

 Ala Glu Thr Glu Lys Glu Lys Gln Asp Trp Ile Glu Ala Val Gln
                 665                 670                 675

 Gln Ser Ile Ala Glu Thr Leu Ser Asp Tyr Glu Val Ala Glu Lys
                 680                 685                 690

 Ile Trp Phe Asn Glu Ser Asn Arg Ser Cys Ala Asp Cys Lys Ala
                 695                 700                 705

 Pro Asp Pro Asp Trp Ala Ser Ile Asn Leu Cys Val Val Ile Cys
                 710                 715                 720

 Lys Lys Cys Ala Gly Gln His Arg Ser Leu Gly Pro Lys Asp Ser
                 725                 730                 735

 Lys Val Arg Ser Leu Lys Met Asp Ala Ser Ile Trp Ser Asn Glu
                 740                 745                 750

 Leu Ile Glu Leu Phe Ile Val Ile Gly Asn Lys Arg Ala Asn Asp
                 755                 760                 765

 Phe Trp Ala Gly Asn Leu Gln Lys Asp Glu Glu Leu His Met Asp
                 770                 775                 780

 Ser Pro Val Glu Lys Arg Lys Asn Phe Ile Thr Gln Lys Tyr Lys
                 785                 790                 795

 Glu Gly Lys Phe Arg Lys Thr Leu Leu Ala Ser Leu Thr Lys Glu
                 800                 805                 810

 Glu Leu Asn Lys Ala Leu Cys Ala Ala Val Val Lys Pro Asp Val
                 815                 820                 825

 Leu Glu Thr Met Ala Leu Leu Phe Ser Gly Ala Asp Val Met Cys
                 830                 835                 840

 Ala Thr Gly Asp Pro Val His Ser Thr Pro Tyr Leu Leu Ala Lys
                 845                 850                 855

 Lys Ala Gly Gln Ser Leu Gln Met Glu Phe Leu Tyr His Asn Lys
                 860                 865                 870

 Phe Ser Asp Phe Pro Gln His Asp Ile His Ser Glu Gly Val Leu
                 875                 880                 885

 Ser Gln Glu Ser Ser Gln Ser Thr Phe Leu Cys Asp Phe Leu Tyr
                 890                 895                 900

 Gln Ala Pro Ser Ala Ala Ser Lys Leu Ser Ser Glu Lys Lys Leu
                 905                 910                 915

 Leu Glu Glu Thr Asn Lys Lys Trp Cys Val Leu Glu Gly Gly Phe
                 920                 925                 930

 Leu Ser Tyr Tyr Glu Asn Asp Lys Ser Thr Thr Pro Asn Gly Thr
                 935                 940                 945

 Ile Asn Ile Asn Glu Val Ile Cys Leu Ala Ile His Lys Glu Asp
                 950                 955                 960

 Phe Tyr Leu Asn Thr Gly Pro Ile Phe Ile Phe Glu Ile Tyr Leu
                 965                 970                 975

 Pro Ser Glu Arg Val Phe Leu Phe Gly Ala Glu Thr Ser Gln Ala
                 980                 985                 990

 Gln Arg Lys Trp Thr Glu Ala Ile Ala Lys His Phe Val Pro Leu
                 995                1000                1005

 Phe Ala Glu Asn Leu Thr Glu Ala Asp Tyr Asp Leu Ile Gly Gln
                1010                1015                1020

 Leu Phe Tyr Lys Asp Cys His Ala Leu Asp Gln Trp Arg Lys Gly
                1025                1030                1035

 Trp Phe Ala Met Asp Lys Ser Ser Leu His Phe Cys Leu Gln Met
                1040                1045                1050

 Gln Glu Val Gln Gly Asp Arg Met His Leu Arg Arg Leu Gln Glu
                1055                1060                1065

 Leu Thr Ile Ser Thr Met Val Gln Asn Gly Glu Lys Leu Asp Val
                1070                1075                1080

 Leu Leu Leu Val Glu Lys Gly Arg Thr Leu Tyr Ile His Gly His
                1085                1090                1095

 Thr Lys Leu Asp Phe Thr Val Trp His Thr Ala Ile Glu Lys Ala
                1100                1105                1110

 Ala Gly Thr Asp Gly Asn Ala Leu Gln Asp Gln Gln Leu Ser Lys
                1115                1120                1125

 Asn Asp Val Pro Ile Ile Val Asn Ser Cys Ile Ala Phe Val Thr
                1130                1135                1140

 Gln Tyr Gly Leu Gly Cys Lys Tyr Ile Tyr Gln Lys Asn Gly Asp
                1145                1150                1155

 Pro Leu His Ile Ser Glu Leu Leu Glu Ser Phe Lys Lys Asp Ala
                1160                1165                1170

 Arg Ser Phe Lys Leu Arg Ala Gly Lys His Gln Leu Glu Asp Val
                1175                1180                1185

 Thr Ala Val Leu Lys Ser Phe Leu Ser Asp Ile Asp Asp Ala Leu
                1190                1195                1200

 Leu Thr Lys Glu Leu Tyr Pro Tyr Trp Ile Ser Ala Leu Asp Thr
                1205                1210                1215

 Gln Asp Asp Lys Glu Arg Ile Lys Lys Tyr Gly Ala Phe Ile Arg
                1220                1225                1230

 Ser Leu Pro Gly Val Asn Arg Ala Thr Leu Ala Ala Ile Ile Glu
                1235                1240                1245

 His Leu Tyr Arg Val Gln Lys Cys Ser Glu Ile Asn His Met Asn
                1250                1255                1260

 Ala His Asn Leu Ala Leu Val Phe Ser Ser Cys Leu Phe Gln Thr
                1265                1270                1275

 Lys Gly Gln Thr Ser Glu Glu Val Asn Val Ile Glu Asp Leu Ile
                1280                1285                1290

 Asn Asn Tyr Val Glu Ile Phe Glu Val Lys Glu Asp Gln Val Lys
                1295                1300                1305

 Gln Met Asp Ile Glu Asn Ser Phe Ile Thr Lys Trp Lys Asp Thr
                1310                1315                1320

 Gln Val Ser Gln Ala Gly Asp Leu Leu Ile Glu Val Tyr Val Glu
                1325                1330                1335

 Arg Lys Glu Pro Asp Cys Ser Ile Ile Ile Arg Ile Ser Pro Val
                1340                1345                1350

 Met Glu Ala Glu Glu Leu Thr Asn Asp Ile Leu Ala Ile Lys Asn
                1355                1360                1365

 Ile Ile Pro Thr Lys Gly Asp Ile Trp Ala Thr Phe Glu Val Ile
                1370                1375                1380

 Glu Asn Glu Glu Leu Glu Arg Pro Leu His Tyr Lys Glu Asn Val
                1385                1390                1395

 Leu Glu Gln Val Leu Arg Trp Ser Ser Leu Ala Glu Pro Gly Ser
                1400                1405                1410

 Ala Tyr Leu Val Val Lys Arg Phe Leu Thr Ala Asp Thr Ile Lys
                1415                1420                1425

 His Cys Ser Asp Arg Ser Thr Leu Gly Ser Ile Lys Glu Gly Ile
                1430                1435                1440

 Leu Lys Ile Lys Glu Glu Pro Ser Lys Ile Leu Ser Gly Asn Lys
                1445                1450                1455

 Phe Gln Asp Arg Tyr Phe Val Leu Arg Asp Gly Phe Leu Phe Leu
                1460                1465                1470

 Tyr Lys Asp Val Lys Ser Ser Lys His Asp Lys Met Phe Ser Leu
                1475                1480                1485

 Ser Ser Met Lys Phe Tyr Arg Gly Val Lys Lys Lys Met Lys Pro
                1490                1495                1500

 Pro Thr Ser Trp Gly Leu Thr Ala Tyr Ser Glu Lys His His Trp
                1505                1510                1515

 His Leu Cys Cys Asp Ser Ser Arg Thr Gln Thr Glu Trp Met Thr
                1520                1525                1530

 Ser Ile Phe Ile Ala Gln His Glu Tyr Asp Ile Trp Pro Pro Ala
                1535                1540                1545

 Gly Lys Glu Arg Lys Arg Ser Ile Thr Lys Asn Pro Lys Ile Gly
                1550                1555                1560

 Gly Leu Pro Leu Ile Pro Ile Gln His Glu Gly Asn Ala Thr Leu
                1565                1570                1575

 Ala Arg Lys Asn Ile Glu Ser Ala Arg Ala Glu Leu Glu Arg Leu
                1580                1585                1590

 Arg Leu Ser Glu Lys Cys Asp Lys Glu Ser Val Asp Ser Ser Leu
                1595                1600                1605

 Lys Glu Arg Ala Ser Met Val Ala His Cys Leu Glu His Lys Asp
                1610                1615                1620

 Asp Lys Leu Arg Asn Arg Pro Arg Lys His Arg Ser Phe Asn Cys
                1625                1630                1635

 Leu Glu Asp Thr Glu Pro Glu Ala Pro Leu Gly Gln Pro Lys Gly
                1640                1645                1650

 His Lys Gly Leu Lys Thr Leu Arg Lys Thr Glu Asp Arg Asn Ser
                1655                1660                1665

 Lys Ala Thr Leu Asp Ser Asp His Lys Leu Pro Ser Arg Val Ile
                1670                1675                1680

 Glu Glu Leu Asn Val Val Leu Gln Arg Ser Arg Thr Leu Pro Lys
                1685                1690                1695

 Glu Leu Gln Asp Glu Gln Ile Leu Lys
                1700

<210> 2816
<211> 3292
<212> DNA
<213> Homo sapien

<400> 2816
 cggctgcgca ctgggcgctc tcgcccgaga agccgcagtc tcgagagcgt 50

 caacgaggtg tttcggtagt ctctggccat cctttctgcg cacccggtgt 100

 cgctgggctg caccccgggc ggggacgtcc gccgggcacg ggagggggcc 150

 aagatgccga tcaataaatc agagaagcca gaaagctgcg ataatgtgaa 200

 ggttgttgtt aggtgccggc ccctcaatga gagagagaaa tcaatgtgct 250

 acaaacaggc tgtcagtgtg gatgagatga ggggaactat cactgtacat 300

 aagactgatt cttccaatga acctccaaag acatttactt ttgatactgt 350

 ttttggacca gagagtaaac aacttgatgt ttataactta actgcaagac 400

 ctattattga ttctgtactt gaaggctaca atgggactat ttttgcatat 450

 ggacaaaccg gaacaggcaa aacttttacc atggaaggtg ttcgagctat 500

 tcctgaactt agaggaataa ttcccaattc atttgctcac atatttggtc 550

 atattgcaaa agcggagggt gatacaagat ttttggttcg agtgtcttat 600

 ttgggaatat ataatgaaga agttcgtgac cttttgggca aggatcagac 650

 acaaaggtta gaggttatag aaagacctga tgtgggagtt tatatcaaag 700

 atttatcagc ttatgtggta aataatgctg atgatatgga tagaattatg 750

 acgctaggcc acaaaaatcg ttctgttggt gcaactaata tgaacgaaca 800

 tagttcccgt tcccatgcca tctttacaat tactatagaa tgcagtgaaa 850

 aaggcattga tggtaacatg catgtcagga tggggaagct ccatcttgta 900

 gatcttgctg gttcagaaag acaggcaaaa actggagcta ctggacagcg 950

 cctaaaggaa gctacaaaaa tcaatctttc actttccacc cttggtaatg 1000

 taatttctgc cttggttgat ggaaaaagca ctcatgtgcc ttatcgtaac 1050

 tctaaactga ctcgtcttct tcaggattcc ttaggaggaa attcaaaaac 1100

 catgatgtgt gcaaatattg ggccagcaga ttacaattat gatgaaacta 1150

 tcagtacatt acggtatgcc aatcgtgcta agaatattaa aaataaagct 1200

 agaattaatg aagatccaaa ggatgctttg ctgcgtcagt tccagaaaga 1250

 aatagaagaa ctgaaaaaga agcttgaaga aggagaagaa atatcaggct 1300

 ctgatatcag tgggtcagag gaagatgatg atgaagaggg tgaggttgga 1350

 gaagatggag agaaaaggaa aaaaagaagg gatcaaacag gaaaaaagaa 1400

 agtctcccca gacaagatga ttgaaatgca agcaaaaatt gatgaggaga 1450

 gaaaagcact tgaaacaaag ctcgacatgg aagaagaaga aagaaacaag 1500

 gctagagctg aattagagaa acgggaaaaa gatcttctta aagcccaaca 1550

 agagcatcag tctttgctgg aaaaattatc tgccctggaa aagaaggtaa 1600

 ttgttggtgg ggttgacttg ttggccaaag ctgaggaaca agagaaactt 1650

 cttgaagaat ctaacatgga actggaagaa aggaggaaaa gagcagagca 1700

 acttcgcaga gaacttgagg aaaaagagca agaacgcttg gatattgaag 1750

 aaaaatatac cagtttgcaa gaggaagcac agggaaagac caagaagtta 1800

 aagaaagttt ggactatgct gatggctgca aagtcagaga tggctgatct 1850

 ccaacaagaa catcagaggg aaattgaagg cctactggag aacattcggc 1900

 aacttagccg ggagcttcga cttcagatgc ttattattga taactttata 1950

 cctcgggatt atcaggaaat gattgaaaac tatgtccatt ggaatgaaga 2000

 cataggagaa tggcagctaa aatgtgttgc ttatacagga aataacatga 2050

 ggaagcaaac cccagtacct gataaaaagg agaaagatcc ctttgaggtg 2100

 gacctttctc acgtgtatct tgcctatact gaggagagtc tgcgtcagtc 2150

 tttgatgaaa ctagaaagac cacgaacttc aaaggggaaa gcaaggccaa 2200

 agacagggag aagaaagcgt tctgcaaagc ctgaaactgt aattgactct 2250

 ttactgcagt aaatgttaca gacttaaagt cacaataaaa attagtgata 2300

 ttctcatgcc tggacaaaat ctttaattaa aacagtgaag acttctctat 2350

 aatttcaatt aatggaagtt gtagatcaat gaataagact ggaaataata 2400

 atttgcttaa gaacttttag tctacatata ttaatataac attaaaattg 2450

 tacaactggt gattgttcaa attgttgtac tactactctt caattgtact 2500

 gtgcagggaa gttgggggaa cagttcatac tatagagagt tacagtttag 2550

 atgtatgtgt aaatcgatta gctatttatc caactactgt atatttaggt 2600

 aactagaatt tcaaagtaga aaaaaaaaaa actgtgtcct gttttgcaca 2650

 tagaaagaag cagatcagat tgtcctatgt tgcgctgtta tatatgaatg 2700

 tttggactgt acatctaaag aatgattccg tcctaacacc cacccagcct 2750

 gtttgaacac attctaattg tctaacattt gttgcatttt aagtatgaga 2800

 tgactgatct tatgaatgtt ttgtagaaaa tgttataatt taacagtctt 2850

 tgcgagtata catgtttttt aacaagttgg aaatgtttca tctgaacctt 2900

 tcctaacttt tttttgccag tttgagttca aatcaaatac accttaagtt 2950

 ctggtttcat gttctcttga aacattgaat tgtacgtaaa tataaaggat 3000

 ctactgttgc ggaaaattaa gaagctaaat actgctcagt tatctttgcc 3050

 tgcgtgtata tttttaaaaa ttcactctga agtgttatgg atgcttttct 3100

 ttgagttcta aattttggtg ggaattactt tatgtctccc agttaagaag 3150

 agtctccatt ttccagaaaa tacagctaag caagaaaaat atcttttaaa 3200

 tactttgcct ttaaaacact ttttattttg tttttctatt ttaaaaataa 3250

 aatattattt tctgaaaaaa aaaaagaaaa aaaaaaaaaa aa 3292

<210> 2817
<211> 702
<212> PRT
<213> Homo sapien

<400> 2817
 Met Pro Ile Asn Lys Ser Glu Lys Pro Glu Ser Cys Asp Asn Val
   1               5                  10                  15

 Lys Val Val Val Arg Cys Arg Pro Leu Asn Glu Arg Glu Lys Ser
                  20                  25                  30

 Met Cys Tyr Lys Gln Ala Val Ser Val Asp Glu Met Arg Gly Thr
                  35                  40                  45

 Ile Thr Val His Lys Thr Asp Ser Ser Asn Glu Pro Pro Lys Thr
                  50                  55                  60

 Phe Thr Phe Asp Thr Val Phe Gly Pro Glu Ser Lys Gln Leu Asp
                  65                  70                  75

 Val Tyr Asn Leu Thr Ala Arg Pro Ile Ile Asp Ser Val Leu Glu
                  80                  85                  90

 Gly Tyr Asn Gly Thr Ile Phe Ala Tyr Gly Gln Thr Gly Thr Gly
                  95                 100                 105

 Lys Thr Phe Thr Met Glu Gly Val Arg Ala Ile Pro Glu Leu Arg
                 110                 115                 120

 Gly Ile Ile Pro Asn Ser Phe Ala His Ile Phe Gly His Ile Ala
                 125                 130                 135

 Lys Ala Glu Gly Asp Thr Arg Phe Leu Val Arg Val Ser Tyr Leu
                 140                 145                 150

 Gly Ile Tyr Asn Glu Glu Val Arg Asp Leu Leu Gly Lys Asp Gln
                 155                 160                 165

 Thr Gln Arg Leu Glu Val Ile Glu Arg Pro Asp Val Gly Val Tyr
                 170                 175                 180

 Ile Lys Asp Leu Ser Ala Tyr Val Val Asn Asn Ala Asp Asp Met
                 185                 190                 195

 Asp Arg Ile Met Thr Leu Gly His Lys Asn Arg Ser Val Gly Ala
                 200                 205                 210

 Thr Asn Met Asn Glu His Ser Ser Arg Ser His Ala Ile Phe Thr
                 215                 220                 225

 Ile Thr Ile Glu Cys Ser Glu Lys Gly Ile Asp Gly Asn Met His
                 230                 235                 240

 Val Arg Met Gly Lys Leu His Leu Val Asp Leu Ala Gly Ser Glu
                 245                 250                 255

 Arg Gln Ala Lys Thr Gly Ala Thr Gly Gln Arg Leu Lys Glu Ala
                 260                 265                 270

 Thr Lys Ile Asn Leu Ser Leu Ser Thr Leu Gly Asn Val Ile Ser
                 275                 280                 285

 Ala Leu Val Asp Gly Lys Ser Thr His Val Pro Tyr Arg Asn Ser
                 290                 295                 300

 Lys Leu Thr Arg Leu Leu Gln Asp Ser Leu Gly Gly Asn Ser Lys
                 305                 310                 315

 Thr Met Met Cys Ala Asn Ile Gly Pro Ala Asp Tyr Asn Tyr Asp
                 320                 325                 330

 Glu Thr Ile Ser Thr Leu Arg Tyr Ala Asn Arg Ala Lys Asn Ile
                 335                 340                 345

 Lys Asn Lys Ala Arg Ile Asn Glu Asp Pro Lys Asp Ala Leu Leu
                 350                 355                 360

 Arg Gln Phe Gln Lys Glu Ile Glu Glu Leu Lys Lys Lys Leu Glu
                 365                 370                 375

 Glu Gly Glu Glu Ile Ser Gly Ser Asp Ile Ser Gly Ser Glu Glu
                 380                 385                 390

 Asp Asp Asp Glu Glu Gly Glu Val Gly Glu Asp Gly Glu Lys Arg
                 395                 400                 405

 Lys Lys Arg Arg Asp Gln Thr Gly Lys Lys Lys Val Ser Pro Asp
                 410                 415                 420

 Lys Met Ile Glu Met Gln Ala Lys Ile Asp Glu Glu Arg Lys Ala
                 425                 430                 435

 Leu Glu Thr Lys Leu Asp Met Glu Glu Glu Glu Arg Asn Lys Ala
                 440                 445                 450

 Arg Ala Glu Leu Glu Lys Arg Glu Lys Asp Leu Leu Lys Ala Gln
                 455                 460                 465

 Gln Glu His Gln Ser Leu Leu Glu Lys Leu Ser Ala Leu Glu Lys
                 470                 475                 480

 Lys Val Ile Val Gly Gly Val Asp Leu Leu Ala Lys Ala Glu Glu
                 485                 490                 495

 Gln Glu Lys Leu Leu Glu Glu Ser Asn Met Glu Leu Glu Glu Arg
                 500                 505                 510

 Arg Lys Arg Ala Glu Gln Leu Arg Arg Glu Leu Glu Glu Lys Glu
                 515                 520                 525

 Gln Glu Arg Leu Asp Ile Glu Glu Lys Tyr Thr Ser Leu Gln Glu
                 530                 535                 540

 Glu Ala Gln Gly Lys Thr Lys Lys Leu Lys Lys Val Trp Thr Met
                 545                 550                 555

 Leu Met Ala Ala Lys Ser Glu Met Ala Asp Leu Gln Gln Glu His
                 560                 565                 570

 Gln Arg Glu Ile Glu Gly Leu Leu Glu Asn Ile Arg Gln Leu Ser
                 575                 580                 585

 Arg Glu Leu Arg Leu Gln Met Leu Ile Ile Asp Asn Phe Ile Pro
                 590                 595                 600

 Arg Asp Tyr Gln Glu Met Ile Glu Asn Tyr Val His Trp Asn Glu
                 605                 610                 615

 Asp Ile Gly Glu Trp Gln Leu Lys Cys Val Ala Tyr Thr Gly Asn
                 620                 625                 630

 Asn Met Arg Lys Gln Thr Pro Val Pro Asp Lys Lys Glu Lys Asp
                 635                 640                 645

 Pro Phe Glu Val Asp Leu Ser His Val Tyr Leu Ala Tyr Thr Glu
                 650                 655                 660

 Glu Ser Leu Arg Gln Ser Leu Met Lys Leu Glu Arg Pro Arg Thr
                 665                 670                 675

 Ser Lys Gly Lys Ala Arg Pro Lys Thr Gly Arg Arg Lys Arg Ser
                 680                 685                 690

 Ala Lys Pro Glu Thr Val Ile Asp Ser Leu Leu Gln
                 695                 700

<210> 2818
<211> 468
<212> DNA
<213> Homo sapien

<400> 2818
 gccccctccc ctgactatca aagcagcggc cggctgttgg ggtccaccac 50

 gccttccacc tgccccactg cttcttcgct tctctcttgg aaagtccagt 100

 ctctcctcgg cttgcaatgg accccaactg ctcctgcgcc gctggtgtct 150

 cctgcacctg cgctggttcc tgcaagtgca aagagtgcaa atgcacctcc 200

 tgcaagaaga gctgctgctc ctgctgcccc gtgggctgta gcaagtgtgc 250

 ccagggctgt gtttgcaaag gggcgtcaga gaagtgcagc tgctgcgact 300

 gatgccagga caacctttct cccagatgta aacagagaga catgtacaaa 350

 cctggatttt tttttatacc accttgaccc atttgctaca ttccttttcc 400

 tgtgaaatat gtgagtgata attaaacact ttagacccaa aaaaaaaaaa 450

 aaaaaaaaaa aaaaaaaa 468

<210> 2819
<211> 61
<212> PRT
<213> Homo sapien

<400> 2819
 Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Val Ser Cys Thr Cys
   1               5                  10                  15

 Ala Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ser Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Val Cys Lys Gly Ala Ser Glu Lys Cys Ser Cys Cys
                  50                  55                  60

 Asp


<210> 2820
<211> 1776
<212> DNA
<213> Mus musculus

<400> 2820
 gcggagcgag aggctgagag agtcggagac actatccgct tccatccgtc 50

 gcgcagaccc tgccggagcc gctgccgcta tggatgatcg agaggatctg 100

 gtgtaccagg cgaagctggc cgagcaggct gagcgatacg acgaaatggt 150

 ggagtcaatg aagaaagtag cagggatgga tgtggagctg acagttgaag 200

 aaagaaacct cctatctgtt gcatataaga atgtgattgg agctagaaga 250

 gcctcctgga gaataatcag cagcattgaa cagaaagaag aaaacaaggg 300

 aggagaagac aagctaaaaa tgattcggga atatcggcaa atggttgaga 350

 ctgagctaaa gttaatctgt tgtgacattc tggatgtact ggacaaacac 400

 ctcattccag cagctaacac tggcgagtcc aaggttttct attataaaat 450

 gaaaggggac taccacaggt atctggcaga atttgccaca ggaaacgaca 500

 ggaaggaggc tgcggagaac agcctagtgg cttataaagc tgctagtgat 550

 attgcaatga cagaacttcc accaacgcat cctattcgct taggtcttgc 600

 tctcaatttt tccgtattct actacgaaat tcttaattcc cctgaccgtg 650

 cctgcaggtt ggcaaaagca gcttttgatg atgcaattgc agaactggat 700

 acgctgagtg aagaaagcta taaggactct acacttatca tgcagttgtt 750

 acgtgataat ctgacactat ggacttcaga catgcagggt gacggtgaag 800

 agcagaataa agaagcgctg caggacgtgg aagacgaaaa tcagtgagac 850

 ataagccaac aagagaaacc atctctgacc accccctcct ccccatccca 900

 ccctttggaa actccccatt gtcactgaga accaccaaat ctgactttta 950

 catttggtct cagaatttag gttcctgccc tgttggtttt tttttttttt 1000

 ttttttaaac agttttcaaa agttcttaaa ggcaagagtg aatttctgtg 1050

 gattttactg gtcccagctt ttaggttctt taagacacta acaggactac 1100

 atagaggctt tttcagcatt actgtgtcgt ctccgtgcca gatgtggcaa 1150

 gatcaccatt agcaaatgga aattacattt gaaagccatt agacttatag 1200

 gtgatgcaag catctaagag agaggttaat cacactatag aggcataagt 1250

 ggtatcagtt ttcatttttc taattgttta aactgtgttt tataccagtg 1300

 tttgcaagta attgggtgtt agcttgagat ggttaaaggt ggtttgggga 1350

 gggacttcgt tgtaatggtt ttgctgtaaa aaatgtttcc aactccgctg 1400

 aaatgttgct gaaaagcatg gtgctggtaa cagttcaaca atccgtggct 1450

 gctcattctt gcctacttta ctctcccact gaagcaggtt agcgttgaag 1500

 gtggtatgga aaagcctgca tgcctgttca attcttttgt ttcttctcct 1550

 tccccctccc cctacctcct tcccctcact cctcccctcc ttcgctcgct 1600

 caacctcttt tgttcagtat gtgtaacttg aagctaattt gtactactgg 1650

 atatctgact ggagccacag atacagaatc tgtattgttc ttactgaaac 1700

 acagcatgga attaacatta aacttaaata aaacaaacct aaattaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaa 1776

<210> 2821
<211> 255
<212> PRT
<213> Mus musculus

<400> 2821
 Met Asp Asp Arg Glu Asp Leu Val Tyr Gln Ala Lys Leu Ala Glu
   1               5                  10                  15

 Gln Ala Glu Arg Tyr Asp Glu Met Val Glu Ser Met Lys Lys Val
                  20                  25                  30

 Ala Gly Met Asp Val Glu Leu Thr Val Glu Glu Arg Asn Leu Leu
                  35                  40                  45

 Ser Val Ala Tyr Lys Asn Val Ile Gly Ala Arg Arg Ala Ser Trp
                  50                  55                  60

 Arg Ile Ile Ser Ser Ile Glu Gln Lys Glu Glu Asn Lys Gly Gly
                  65                  70                  75

 Glu Asp Lys Leu Lys Met Ile Arg Glu Tyr Arg Gln Met Val Glu
                  80                  85                  90

 Thr Glu Leu Lys Leu Ile Cys Cys Asp Ile Leu Asp Val Leu Asp
                  95                 100                 105

 Lys His Leu Ile Pro Ala Ala Asn Thr Gly Glu Ser Lys Val Phe
                 110                 115                 120

 Tyr Tyr Lys Met Lys Gly Asp Tyr His Arg Tyr Leu Ala Glu Phe
                 125                 130                 135

 Ala Thr Gly Asn Asp Arg Lys Glu Ala Ala Glu Asn Ser Leu Val
                 140                 145                 150

 Ala Tyr Lys Ala Ala Ser Asp Ile Ala Met Thr Glu Leu Pro Pro
                 155                 160                 165

 Thr His Pro Ile Arg Leu Gly Leu Ala Leu Asn Phe Ser Val Phe
                 170                 175                 180

 Tyr Tyr Glu Ile Leu Asn Ser Pro Asp Arg Ala Cys Arg Leu Ala
                 185                 190                 195

 Lys Ala Ala Phe Asp Asp Ala Ile Ala Glu Leu Asp Thr Leu Ser
                 200                 205                 210

 Glu Glu Ser Tyr Lys Asp Ser Thr Leu Ile Met Gln Leu Leu Arg
                 215                 220                 225

 Asp Asn Leu Thr Leu Trp Thr Ser Asp Met Gln Gly Asp Gly Glu
                 230                 235                 240

 Glu Gln Asn Lys Glu Ala Leu Gln Asp Val Glu Asp Glu Asn Gln
                 245                 250                 255

<210> 2822
<211> 2795
<212> DNA
<213> Homo sapien

<400> 2822
 atcagcgagg gattcacggc gaaatgagac tgttcgtgag tgatggcgtc 50

 ccgggttgct tgccggtgct ggccgccgcc gggagagccc ggggcagagc 100

 agaggtgctc atcagcactg taggcccgga agattgtgtg gtcccgttcc 150

 tgacccggcc taaggtccct gtcttgcagc tggatagcgg caactacctc 200

 ttctccacta gtgcaatctg ccgatatttt tttttgttat ctggctggga 250

 gcaagatgac ctcactaacc agtggctgga atgggaagcg acagagctgc 300

 agccagcttt gtctgctgcc ctgtactatt tagtggtcca aggcaagaag 350

 ggggaagatg ttcttggttc agtgcggaga gccctgactc acattgacca 400

 cagcttgagt cgtcagaact gtcctttcct ggctggggag acagaatctc 450

 tagccgacat tgttttgtgg ggagccctat acccattact gcaagatccc 500

 gcctacctcc ctgaggagct gagtgccctg cacagctggt tccagacact 550

 gagtacccag gaaccatgtc agcgagctgc agagactgta ctgaaacagc 600

 aaggtgtcct ggctctccgg ccttacctcc aaaagcagcc ccagcccagc 650

 cccgctgagg gaagggctgt caccaatgag cctgaggagg aggagctggc 700

 taccctatct gaggaggaga ttgctatggc tgttactgct tgggagaagg 750

 gcctagaaag tttgcccccg ctgcggcccc agcagaatcc agtgttgcct 800

 gtggctggag aaaggaatgt gctcatcacc agtgccctcc cttacgtcaa 850

 caatgtcccc caccttggga acatcattgg ttgtgtgctc agtgccgatg 900

 tctttgccag gtactctcgc ctccgccagt ggaacaccct ctatctgtgt 950

 gggacagatg agtatggtac agcaacagag accaaggctc tggaggaggg 1000

 actaaccccc caggagatct gcgacaagta ccacatcatc catgctgaca 1050

 tctaccgctg gtttaacatt tcgtttgata tttttggtcg caccaccact 1100

 ccacagcaga ccaaaatcac ccaggacatt ttccagcagt tgctgaaacg 1150

 aggttttgtg ctgcaagata ctgtggagca actgcgatgt gagcactgtg 1200

 ctcgcttcct ggctgaccgc ttcgtggagg gcgtgtgtcc cttctgtggc 1250

 tatgaggagg ctcggggtga ccagtgtgac aagtgtggca agctcatcaa 1300

 tgctgtcgag cttaagaagc ctcagtgtaa agtctgccga tcatgccctg 1350

 tggtgcagtc gagccagcac ctgtttctgg acctgcctaa gctggagaag 1400

 cgactggagg agtggttggg gaggacattg cctggcagtg actggacacc 1450

 caatgcccag tttatcaccc gttcttggct tcgggatggc ctcaagccac 1500

 gctgcataac ccgagacctc aaatggggaa cccctgtacc cttagaaggt 1550

 tttgaagaca aggtattcta tgtctggttt gatgccacta ttggctatct 1600

 gtccatcaca gccaactaca cagaccagtg ggagagatgg tggaagaacc 1650

 cagagcaagt ggacctgtat cagttcatgg ccaaagacaa tgttcctttc 1700

 catagcttag tctttccttg ctcagcccta ggagctgagg ataactatac 1750

 cttggtcagc cacctcattg ctacagagta cctgaactat gaggatggga 1800

 aattctctaa gagccgcggt gtgggagtgt ttggggacat ggcccaggac 1850

 acggggatcc ctgctgacat ctggcgcttc tatctgctgt acattcggcc 1900

 tgagggccag gacagtgctt tctcctggac ggacctgctg ctgaagaata 1950

 attctgagct gcttaacaac ctgggcaact tcatcaacag agctgggatg 2000

 tttgtgtcta agttctttgg gggctatgtg cctgagatgg tgctcacccc 2050

 tgatgatcag cgcctgctgg cccatgtcac cctggagctc cagcactatc 2100

 accagctact tgagaaggtt cggatccggg atgccttgcg cagtatcctc 2150

 accatatctc gacatggcaa ccaatatatt caggtgaatg agccctggaa 2200

 gcggattaaa ggcagtgagg ctgacaggca acgggcagga acagtgactg 2250

 gcttggcagt gaatatagct gccttgctct ctgtcatgct tcagccttac 2300

 atgcccacgg ttagtgccac aatccaggcc cagctgcagc tcccacctcc 2350

 agcctgcagt atcctgctga caaacttcct gtgtacctta ccagcaggac 2400

 accagattgg cacagtcagt cccttgttcc aaaaattgga aaatgaccag 2450

 attgaaagtt taaggcagcg ctttggaggg ggccaggcaa aaacgtcccc 2500

 gaagccagca gttgtagaga ctgttacaac agccaagcca cagcagatac 2550

 aagcgctgat ggatgaagtg acaaaacaag gaaacattgt ccgagaactg 2600

 aaagcacaaa aggcagacaa gaacgaggtt gctgcggagg tggcgaaact 2650

 cttggatcta aagaaacagt tggctgtagc tgaggggaaa ccccctgaag 2700

 cccctaaagg caagaagaaa aagtaaaaga ccttggctca tagaaagtca 2750

 ctttaataga tagggacagt aataaataaa tgtacaatct ctata 2795

<210> 2823
<211> 900
<212> PRT
<213> Homo sapien

<400> 2823
 Met Arg Leu Phe Val Ser Asp Gly Val Pro Gly Cys Leu Pro Val
   1               5                  10                  15

 Leu Ala Ala Ala Gly Arg Ala Arg Gly Arg Ala Glu Val Leu Ile
                  20                  25                  30

 Ser Thr Val Gly Pro Glu Asp Cys Val Val Pro Phe Leu Thr Arg
                  35                  40                  45

 Pro Lys Val Pro Val Leu Gln Leu Asp Ser Gly Asn Tyr Leu Phe
                  50                  55                  60

 Ser Thr Ser Ala Ile Cys Arg Tyr Phe Phe Leu Leu Ser Gly Trp
                  65                  70                  75

 Glu Gln Asp Asp Leu Thr Asn Gln Trp Leu Glu Trp Glu Ala Thr
                  80                  85                  90

 Glu Leu Gln Pro Ala Leu Ser Ala Ala Leu Tyr Tyr Leu Val Val
                  95                 100                 105

 Gln Gly Lys Lys Gly Glu Asp Val Leu Gly Ser Val Arg Arg Ala
                 110                 115                 120

 Leu Thr His Ile Asp His Ser Leu Ser Arg Gln Asn Cys Pro Phe
                 125                 130                 135

 Leu Ala Gly Glu Thr Glu Ser Leu Ala Asp Ile Val Leu Trp Gly
                 140                 145                 150

 Ala Leu Tyr Pro Leu Leu Gln Asp Pro Ala Tyr Leu Pro Glu Glu
                 155                 160                 165

 Leu Ser Ala Leu His Ser Trp Phe Gln Thr Leu Ser Thr Gln Glu
                 170                 175                 180

 Pro Cys Gln Arg Ala Ala Glu Thr Val Leu Lys Gln Gln Gly Val
                 185                 190                 195

 Leu Ala Leu Arg Pro Tyr Leu Gln Lys Gln Pro Gln Pro Ser Pro
                 200                 205                 210

 Ala Glu Gly Arg Ala Val Thr Asn Glu Pro Glu Glu Glu Glu Leu
                 215                 220                 225

 Ala Thr Leu Ser Glu Glu Glu Ile Ala Met Ala Val Thr Ala Trp
                 230                 235                 240

 Glu Lys Gly Leu Glu Ser Leu Pro Pro Leu Arg Pro Gln Gln Asn
                 245                 250                 255

 Pro Val Leu Pro Val Ala Gly Glu Arg Asn Val Leu Ile Thr Ser
                 260                 265                 270

 Ala Leu Pro Tyr Val Asn Asn Val Pro His Leu Gly Asn Ile Ile
                 275                 280                 285

 Gly Cys Val Leu Ser Ala Asp Val Phe Ala Arg Tyr Ser Arg Leu
                 290                 295                 300

 Arg Gln Trp Asn Thr Leu Tyr Leu Cys Gly Thr Asp Glu Tyr Gly
                 305                 310                 315

 Thr Ala Thr Glu Thr Lys Ala Leu Glu Glu Gly Leu Thr Pro Gln
                 320                 325                 330

 Glu Ile Cys Asp Lys Tyr His Ile Ile His Ala Asp Ile Tyr Arg
                 335                 340                 345

 Trp Phe Asn Ile Ser Phe Asp Ile Phe Gly Arg Thr Thr Thr Pro
                 350                 355                 360

 Gln Gln Thr Lys Ile Thr Gln Asp Ile Phe Gln Gln Leu Leu Lys
                 365                 370                 375

 Arg Gly Phe Val Leu Gln Asp Thr Val Glu Gln Leu Arg Cys Glu
                 380                 385                 390

 His Cys Ala Arg Phe Leu Ala Asp Arg Phe Val Glu Gly Val Cys
                 395                 400                 405

 Pro Phe Cys Gly Tyr Glu Glu Ala Arg Gly Asp Gln Cys Asp Lys
                 410                 415                 420

 Cys Gly Lys Leu Ile Asn Ala Val Glu Leu Lys Lys Pro Gln Cys
                 425                 430                 435

 Lys Val Cys Arg Ser Cys Pro Val Val Gln Ser Ser Gln His Leu
                 440                 445                 450

 Phe Leu Asp Leu Pro Lys Leu Glu Lys Arg Leu Glu Glu Trp Leu
                 455                 460                 465

 Gly Arg Thr Leu Pro Gly Ser Asp Trp Thr Pro Asn Ala Gln Phe
                 470                 475                 480

 Ile Thr Arg Ser Trp Leu Arg Asp Gly Leu Lys Pro Arg Cys Ile
                 485                 490                 495

 Thr Arg Asp Leu Lys Trp Gly Thr Pro Val Pro Leu Glu Gly Phe
                 500                 505                 510

 Glu Asp Lys Val Phe Tyr Val Trp Phe Asp Ala Thr Ile Gly Tyr
                 515                 520                 525

 Leu Ser Ile Thr Ala Asn Tyr Thr Asp Gln Trp Glu Arg Trp Trp
                 530                 535                 540

 Lys Asn Pro Glu Gln Val Asp Leu Tyr Gln Phe Met Ala Lys Asp
                 545                 550                 555

 Asn Val Pro Phe His Ser Leu Val Phe Pro Cys Ser Ala Leu Gly
                 560                 565                 570

 Ala Glu Asp Asn Tyr Thr Leu Val Ser His Leu Ile Ala Thr Glu
                 575                 580                 585

 Tyr Leu Asn Tyr Glu Asp Gly Lys Phe Ser Lys Ser Arg Gly Val
                 590                 595                 600

 Gly Val Phe Gly Asp Met Ala Gln Asp Thr Gly Ile Pro Ala Asp
                 605                 610                 615

 Ile Trp Arg Phe Tyr Leu Leu Tyr Ile Arg Pro Glu Gly Gln Asp
                 620                 625                 630

 Ser Ala Phe Ser Trp Thr Asp Leu Leu Leu Lys Asn Asn Ser Glu
                 635                 640                 645

 Leu Leu Asn Asn Leu Gly Asn Phe Ile Asn Arg Ala Gly Met Phe
                 650                 655                 660

 Val Ser Lys Phe Phe Gly Gly Tyr Val Pro Glu Met Val Leu Thr
                 665                 670                 675

 Pro Asp Asp Gln Arg Leu Leu Ala His Val Thr Leu Glu Leu Gln
                 680                 685                 690

 His Tyr His Gln Leu Leu Glu Lys Val Arg Ile Arg Asp Ala Leu
                 695                 700                 705

 Arg Ser Ile Leu Thr Ile Ser Arg His Gly Asn Gln Tyr Ile Gln
                 710                 715                 720

 Val Asn Glu Pro Trp Lys Arg Ile Lys Gly Ser Glu Ala Asp Arg
                 725                 730                 735

 Gln Arg Ala Gly Thr Val Thr Gly Leu Ala Val Asn Ile Ala Ala
                 740                 745                 750

 Leu Leu Ser Val Met Leu Gln Pro Tyr Met Pro Thr Val Ser Ala
                 755                 760                 765

 Thr Ile Gln Ala Gln Leu Gln Leu Pro Pro Pro Ala Cys Ser Ile
                 770                 775                 780

 Leu Leu Thr Asn Phe Leu Cys Thr Leu Pro Ala Gly His Gln Ile
                 785                 790                 795

 Gly Thr Val Ser Pro Leu Phe Gln Lys Leu Glu Asn Asp Gln Ile
                 800                 805                 810

 Glu Ser Leu Arg Gln Arg Phe Gly Gly Gly Gln Ala Lys Thr Ser
                 815                 820                 825

 Pro Lys Pro Ala Val Val Glu Thr Val Thr Thr Ala Lys Pro Gln
                 830                 835                 840

 Gln Ile Gln Ala Leu Met Asp Glu Val Thr Lys Gln Gly Asn Ile
                 845                 850                 855

 Val Arg Glu Leu Lys Ala Gln Lys Ala Asp Lys Asn Glu Val Ala
                 860                 865                 870

 Ala Glu Val Ala Lys Leu Leu Asp Leu Lys Lys Gln Leu Ala Val
                 875                 880                 885

 Ala Glu Gly Lys Pro Pro Glu Ala Pro Lys Gly Lys Lys Lys Lys
                 890                 895                 900

<210> 2824
<211> 2952
<212> DNA
<213> Homo sapien

<400> 2824
 catgaagaaa aaaaaaattc aaaagatcta cgaattcagg gtaggtttct 50

 tgaaaatatt aataagaaag tctgctagca gactaataca gaggatgatt 100

 gaaataaaca caattagaaa tgacaaaggg aatgtaatta ccactgaccc 150

 cacagaaata gaaacaacca tcagaaacta ctgcaaacac ttctgtgcat 200

 acaaactaga aaacttcaaa gagatggata aattcctgga caaatacacc 250

 ctcccacaac tgagccagga agaaattgat ttgctgaaca gaccaataac 300

 aagctccgaa attgaatcag taataaataa cctaccaatc aaaaaaagcc 350

 cagaacatga tggattccca gccatattct actagaagta caaagaagag 400

 ctggtaccat ttttacagga actatttgaa aatattgagg aggaggaact 450

 cctccccaac tcattctatg aggccaacat catcttgata ccaaaatctg 500

 gcacacacac acacacacac acacacacac acacacacac acacacaaac 550

 ttcaggccaa tacccttgat gaacatcaat gcaaaaatcc tcaacaaaat 600

 acgggcaaac caaatccagc agcacatcaa aaagttaatc catcatgatc 650

 aagtatgctt catccccagg atgcaaggtt gcctcaacat acacgtcaat 700

 taatctgact catcccataa acaaaactaa agataaaaac catgtgatta 750

 tctcaatata tgcagaaaag gctttcaata aaattcaagg cctctccata 800

 ttaaaaactc taaaaaatct gggtattgag gaaacatagc tcaaagtgat 850

 gagctgtttt tgtaccagta tcatgctgtt ttggttgctg tagccctgta 900

 gtatagtttg aagttgggta acatgatgcc tccagctttg ttctttttgc 950

 tgaggattgc ttggctatta gggctctttt tttttttggt tccatatgaa 1000

 ttttgaaata gtttgctcta gttctgtgag gaatgccatt ggtaatttaa 1050

 tagggatgac ttgcatctgt aaattacttt gggcagtatg gccattttaa 1100

 tgatgttgat tcttcctatc catgagcatg aaatgttttt ccatttgttt 1150

 gtgtcttctc tgatttcttt gagcagtgtt ttgtaattct cctagagatc 1200

 tcttagagat ctttcacctc cctggttagc tgtattccta ggtattttat 1250

 tttttctgtg tgtagcaatt atgaatggga ttatgttctt catttgactc 1300

 tctgctttac tgctaggaat ttttgcacat tgattttgta tgctaagact 1350

 ttgctaaagt ttatcagcag aaggagcttt ggggctgaga ctatggggtt 1400

 ttctagatat agaatcatgt catctgtaaa cagagacagt ttgatttcct 1450

 gtctattcct ctcttccctc ctctatttgg atgcccttcc agttttgcac 1500

 attcagtgta atgttggctg tgggtttgcc atggctagct ctcatcattt 1550

 tggcacttcc gactagaagt gcgagagggg ccagtgttgt tgttacctga 1600

 aaggtaagtg cagcccacaa aaatgcagtg aagaagaaga tatatgcata 1650

 tgtttaagtt aatacaattg agatacattt agcagacaga atcaatagag 1700

 ttgatgagtg actgactgga tgtgtgggga gtttatatca ctcccaggtt 1750

 tttgacttgg gcaaccgggc actcaagaag gaaaaagagg atccagggag 1800

 aggaactttt ctgaggactg gggtagggct gaacagctgc attcgagact 1850

 ggtggagggt gggctgggca tgggatgcac aaatggaaat tccactgggt 1900

 ctgcagctca cacataggca tgaccagcat agagatagag aggccccagt 1950

 gctgctgagt aactgtgatt ccccaggtga tggcatcagc tgagaaggga 2000

 aggaagccca tgtgaggaca ctgaagaagg agtgagcaga caataagaag 2050

 cccacagaag acagagaagg aacaactaga gggagaagcc aaggcaggca 2100

 tgtgtgataa catataggaa ctgagggaga ggacatttca agatggaggg 2150

 gatgccatac aacaggacta tgtgatggtt tttggctgtg tccataggaa 2200

 gtcacaacag gcaagggaaa gaaaccagaa cccagtcatg gagttaagaa 2250

 gtgagtcaga gaggagatgg gtagggacag tgaggtaagg cctctttcta 2300

 aggaagtttg gctgaaggat agactagctg gacatatgct ggctgtgtgg 2350

 ggtagaggga ggaatgatgg agggtgggag agccttgagc ctgcgagaag 2400

 agtctcctag aatagagaag ctgaggttaa agttgtggaa gacagtgggg 2450

 ataactgagt gacagataat caggagaaga aaaggagatc cagaatcatg 2500

 acagagagat gacctttgcc aagagcacag ccatctttca ctgtcacaga 2550

 gaggtaggac aaaacgattg gtgttcaaga attggtttgt agcacaatat 2600

 tttaactatg tcctttaaaa agtttctcca cagacactac ccaaagcagt 2650

 ccttcactac agtggcagac agacctgaaa attttcatct gaagcagcag 2700

 agtgaactgc agagtcagag atagaatctc actatgttga ccaggctggt 2750

 cttgaactct tggcacccaa gcgatccttt tgcctggaat cccaaagtgt 2800

 cagatttact gaagaatatt tcattgtaat tactttttat actttatagg 2850

 tcaagagctc tgttttaaag acaaaattta ttgaatatac tttttcaaac 2900

 aaagtttcat gttctaatca ttgtctgatt tcagcattaa atgaaacaca 2950

 gt 2952

<210> 2825
<211> 127
<212> PRT
<213> Homo sapien

<400> 2825
 Met Lys Lys Lys Lys Ile Gln Lys Ile Tyr Glu Phe Arg Val Gly
   1               5                  10                  15

 Phe Leu Lys Ile Leu Ile Arg Lys Ser Ala Ser Arg Leu Ile Gln
                  20                  25                  30

 Arg Met Ile Glu Ile Asn Thr Ile Arg Asn Asp Lys Gly Asn Val
                  35                  40                  45

 Ile Thr Thr Asp Pro Thr Glu Ile Glu Thr Thr Ile Arg Asn Tyr
                  50                  55                  60

 Cys Lys His Phe Cys Ala Tyr Lys Leu Glu Asn Phe Lys Glu Met
                  65                  70                  75

 Asp Lys Phe Leu Asp Lys Tyr Thr Leu Pro Gln Leu Ser Gln Glu
                  80                  85                  90

 Glu Ile Asp Leu Leu Asn Arg Pro Ile Thr Ser Ser Glu Ile Glu
                  95                 100                 105

 Ser Val Ile Asn Asn Leu Pro Ile Lys Lys Ser Pro Glu His Asp
                 110                 115                 120

 Gly Phe Pro Ala Ile Phe Tyr
                 125

<210> 2826
<211> 1577
<212> DNA
<213> Homo sapien

<400> 2826
 ggcacgaggc tgctgtttgt ctacttcctc ctgcttcccc gccgccgccg 50

 ccgccatcat gagggaaatc gtgcacttgc aggccgggca gtgcggcaac 100

 caaatcggcg ccaagttttg ggaggtgatc agcgatgagc acggcatcga 150

 ccccacgggc acctaccacg gggacagcga cctgcagctg gaacgcatca 200

 acgtgtacta caatgaggcc accggcggca agtacgtgcc ccgcgccgtg 250

 ctcgtggatc tggagcccgg caccatggac tccgtgcgct cggggccctt 300

 cgggcagatc ttccggccgg acaacttcgt tttcggtcag agtggtgctg 350

 ggaacaactg ggccaagggg cactacacag aaggcgcgga gctggtggac 400

 tcggtgctgg atgttgtgag aaaggaggct gagagctgtg actgcctgca 450

 gggtttccag ctgacccact ccctgggtgg ggggactggg tctgggatgg 500

 gtaccctcct catcagcaag atccgggagg agtacccaga caggatcatg 550

 aacacgttta gtgtggtgcc ttcgcccaaa gtgtcagaca cagtggtgga 600

 gccctacaac gccaccctct cagtccacca gctcgtagaa aacacagacg 650

 agacctactg cattgataac gaagctctct acgacatttg cttcagaacc 700

 ctaaagctga ccacgcccac ctatggtgac ctgaaccacc tggtgtctgc 750

 taccatgagt ggggtcacca cctgcctgcg cttcccaggc cagctcaatg 800

 ctgacctgcg gaagctggct gtgaacatgg tcccgtttcc ccggctgcac 850

 ttcttcatgc ccggctttgc cccactgacc agccggggca gccagcagta 900

 ccgggcgctg accgtgcccg agctcaccca gcagatgttt gatgccaaga 950

 acatgatggc tgcctgcgac ccccgccatg gccgctacct gacggttgcc 1000

 gccgtgttca ggggccgcat gtccatgaag gaggtggatg agcaaatgct 1050

 taatgtccaa aacaaaaaca gcagctattt tgttgagtgg atccccaaca 1100

 atgtgaaaac ggctgtctgt gacatcccac ctcgggggct aaaaatgtcc 1150

 gccaccttca ttggcaacag cacggccatc caggagctgt tcaagcgcat 1200

 ctccgagcag ttcacggcca tgttccggcg caaggccttc ctgcactggt 1250

 acacgggcga gggcatggac gagatggagt tcaccgaggc cgagagcaac 1300

 atgaatgacc tggtgtccga gtaccagcag taccaggatg ccacagccga 1350

 ggaggagggc gagttcgagg aggaggctga ggaggaggtg gcctagagcc 1400

 ttcagtcact ggggaaagca gggaagcagt gtgaactctt tattcactcc 1450

 cagcctgtcc tgtggcctgt cccactgtgt gcacttgctg ttttccctgt 1500

 ccacatccat gctgtacaga caccaccatt aaagcatttt catagtgaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 1577

<210> 2827
<211> 445
<212> PRT
<213> Homo sapien

<400> 2827
 Met Arg Glu Ile Val His Leu Gln Ala Gly Gln Cys Gly Asn Gln
   1               5                  10                  15

 Ile Gly Ala Lys Phe Trp Glu Val Ile Ser Asp Glu His Gly Ile
                  20                  25                  30

 Asp Pro Thr Gly Thr Tyr His Gly Asp Ser Asp Leu Gln Leu Glu
                  35                  40                  45

 Arg Ile Asn Val Tyr Tyr Asn Glu Ala Thr Gly Gly Lys Tyr Val
                  50                  55                  60

 Pro Arg Ala Val Leu Val Asp Leu Glu Pro Gly Thr Met Asp Ser
                  65                  70                  75

 Val Arg Ser Gly Pro Phe Gly Gln Ile Phe Arg Pro Asp Asn Phe
                  80                  85                  90

 Val Phe Gly Gln Ser Gly Ala Gly Asn Asn Trp Ala Lys Gly His
                  95                 100                 105

 Tyr Thr Glu Gly Ala Glu Leu Val Asp Ser Val Leu Asp Val Val
                 110                 115                 120

 Arg Lys Glu Ala Glu Ser Cys Asp Cys Leu Gln Gly Phe Gln Leu
                 125                 130                 135

 Thr His Ser Leu Gly Gly Gly Thr Gly Ser Gly Met Gly Thr Leu
                 140                 145                 150

 Leu Ile Ser Lys Ile Arg Glu Glu Tyr Pro Asp Arg Ile Met Asn
                 155                 160                 165

 Thr Phe Ser Val Val Pro Ser Pro Lys Val Ser Asp Thr Val Val
                 170                 175                 180

 Glu Pro Tyr Asn Ala Thr Leu Ser Val His Gln Leu Val Glu Asn
                 185                 190                 195

 Thr Asp Glu Thr Tyr Cys Ile Asp Asn Glu Ala Leu Tyr Asp Ile
                 200                 205                 210

 Cys Phe Arg Thr Leu Lys Leu Thr Thr Pro Thr Tyr Gly Asp Leu
                 215                 220                 225

 Asn His Leu Val Ser Ala Thr Met Ser Gly Val Thr Thr Cys Leu
                 230                 235                 240

 Arg Phe Pro Gly Gln Leu Asn Ala Asp Leu Arg Lys Leu Ala Val
                 245                 250                 255

 Asn Met Val Pro Phe Pro Arg Leu His Phe Phe Met Pro Gly Phe
                 260                 265                 270

 Ala Pro Leu Thr Ser Arg Gly Ser Gln Gln Tyr Arg Ala Leu Thr
                 275                 280                 285

 Val Pro Glu Leu Thr Gln Gln Met Phe Asp Ala Lys Asn Met Met
                 290                 295                 300

 Ala Ala Cys Asp Pro Arg His Gly Arg Tyr Leu Thr Val Ala Ala
                 305                 310                 315

 Val Phe Arg Gly Arg Met Ser Met Lys Glu Val Asp Glu Gln Met
                 320                 325                 330

 Leu Asn Val Gln Asn Lys Asn Ser Ser Tyr Phe Val Glu Trp Ile
                 335                 340                 345

 Pro Asn Asn Val Lys Thr Ala Val Cys Asp Ile Pro Pro Arg Gly
                 350                 355                 360

 Leu Lys Met Ser Ala Thr Phe Ile Gly Asn Ser Thr Ala Ile Gln
                 365                 370                 375

 Glu Leu Phe Lys Arg Ile Ser Glu Gln Phe Thr Ala Met Phe Arg
                 380                 385                 390

 Arg Lys Ala Phe Leu His Trp Tyr Thr Gly Glu Gly Met Asp Glu
                 395                 400                 405

 Met Glu Phe Thr Glu Ala Glu Ser Asn Met Asn Asp Leu Val Ser
                 410                 415                 420

 Glu Tyr Gln Gln Tyr Gln Asp Ala Thr Ala Glu Glu Glu Gly Glu
                 425                 430                 435

 Phe Glu Glu Glu Ala Glu Glu Glu Val Ala
                 440                 445

<210> 2828
<211> 2385
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 149
<223> Unknown base

<400> 2828
 ccctaacgac agctcgcccg tgcttcgccc tcgcagctct cctgtgtccc 50

 caaaatgccc ttcccgcgtc ccccgccctt cagcggtgac tgcccagggg 100

 actctgtaac gcgacactca gactgccgag cctgccaggc acttcgcgna 150

 gggcgctagg ggccgggacg cggccgccga gcgtaggttc cggcctttac 200

 tccgagttgc gcacggagcc ccagctgcgg ttgtccgctc tggggatcac 250

 aggccgcgga gacccgggag ccacccgccg ggccccttca gacgacccgc 300

 ttccgcaaac cggccgtggg actccggcgc cgggcggacg aagcggcgcc 350

 gggcggacga agcggctccg ggaagactcg gtcttccccg cccgcctgag 400

 gtcgccgggg cggggcttca gtgacaggcc cgcgcgctac cgcggaaaca 450

 ggaagttggc tgggtgcgcg ccggctccgg ctgcagttcc cgggtccctc 500

 ggccaccgaa gccaccctgc cctggtgaaa gggctcccgc accgcccggt 550

 gctccccatc tgcctggcgt tgtgcgcaga gctggaaagc atggctgtta 600

 taaatgaatt ctgattttgg ggagcagatg ccaacttaga gcctcgtacc 650

 aatctctctg tctttaaaag atgaggtgac ttggtgattt tcctggaaaa 700

 ttataggtgc ccagctaaga cctgaatgcc atcaccctcc ccagggctct 750

 gcagttttct cgtggtgaac ccttgatgga tttgttgttg cttgagaaat 800

 ggcgatgatc gaattggggt ttggaagaca gaattttcat ccattaaaga 850

 ggaagagttc attgctgttg aaactcatag ctgttgtctt tgctgtgctt 900

 ctattttgtg aatttttaat ctattactta gcgatctttc agtgtaattg 950

 gcctgaagtg aaaaccacag cctctgatgg tgaacagacc acacgtgagc 1000

 ctgtgctcaa agccatgttt ttggctgaca cccatttgct tggggaattc 1050

 ctaggccact ggctggacaa attacgaagg gaatggcaga tggagagagc 1100

 gttccagaca gctctgtggt tgctgcagcc ggaagtcgtc ttcatcctgg 1150

 gggatatctt tgatgaaggg aagtggagca cccctgaggc ctgggcggat 1200

 gatgtggagc ggtttcagaa aatgttcaga cacccaagtc atgtacagct 1250

 gaaggtagtt gctggaaacc atgacattgg cttccattat gagatgaaca 1300

 catacaaagt agaacgcttt gagaaagtgt tcagctctga aagactgttt 1350

 tcttggaaag gcattaactt tgtgatggtc aacagcgtgg cgctgaacgg 1400

 ggatggctgt ggcatctgct ctgaaacaga agcagagctc attgaagttt 1450

 ctcacagact gaactgctcc cgagaggcac gtggctccag ccggtgtgga 1500

 cctgggcctc tgctgcccac gtctgcccct gtcctcctgc agcattatcc 1550

 tctgtatcgg agaagtgatg ctaactgttc tggggaagac gctgctcctg 1600

 cagaggaaag ggacatccca tttaaggaga actatgacgt gctttcacgg 1650

 gaggcatcac aaaagctgct gtggtggctc cagccgcgcc tggttctcag 1700

 tggccacacg cacagcgcct gcgaggtgca ccacgggggc cgagtccccg 1750

 agctcagcgt cccatctttc agttggagga acagaaacaa ccccagtttc 1800

 atcatgggta gcatcacgcc cacagactac accctctcca agtgctacct 1850

 cccacgtgag gatgtggttt tgatcatcta ctgtggagag gtgggcttcc 1900

 ttgtggtcct cacactcact cactttgggc ttctagcctc accttttctt 1950

 tctggtttga acttgctcgg aaagcgtaag acaagatgaa gagcaggcgc 2000

 cattataaat atcaaagccc aagaaatgga actttgggca gagatcatgt 2050

 tagaatcaag tggatgatga gaccaattac aggccgtctc tctgcacagc 2100

 acagaaattc tcaatcactg aaatgagtaa ctgcaaaata aatagttgat 2150

 tgtactgttc tcatgctata aaagtggaca ggtactctac aacaaatctg 2200

 ttttctcatt tttatcaaat atatgtatca tcaaaggttg catctgtaca 2250

 gtatgtaaat gctattaatg tcgtcactca catgcacgag agtccttgtt 2300

 cccccaggaa gggcctggtg gccccagcac acacttggga ttatgtgtat 2350

 acataaataa atattgggct gtttccctct tcctg 2385

<210> 2829
<211> 396
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 149
<223> Unknown amino acid

<400> 2829
 Met Ala Met Ile Glu Leu Gly Phe Gly Arg Gln Asn Phe His Pro
   1               5                  10                  15

 Leu Lys Arg Lys Ser Ser Leu Leu Leu Lys Leu Ile Ala Val Val
                  20                  25                  30

 Phe Ala Val Leu Leu Phe Cys Glu Phe Leu Ile Tyr Tyr Leu Ala
                  35                  40                  45

 Ile Phe Gln Cys Asn Trp Pro Glu Val Lys Thr Thr Ala Ser Asp
                  50                  55                  60

 Gly Glu Gln Thr Thr Arg Glu Pro Val Leu Lys Ala Met Phe Leu
                  65                  70                  75

 Ala Asp Thr His Leu Leu Gly Glu Phe Leu Gly His Trp Leu Asp
                  80                  85                  90

 Lys Leu Arg Arg Glu Trp Gln Met Glu Arg Ala Phe Gln Thr Ala
                  95                 100                 105

 Leu Trp Leu Leu Gln Pro Glu Val Val Phe Ile Leu Gly Asp Ile
                 110                 115                 120

 Phe Asp Glu Gly Lys Trp Ser Thr Pro Glu Ala Trp Ala Asp Asp
                 125                 130                 135

 Val Glu Arg Phe Gln Lys Met Phe Arg His Pro Ser His Val Gln
                 140                 145                 150

 Leu Lys Val Val Ala Gly Asn His Asp Ile Gly Phe His Tyr Glu
                 155                 160                 165

 Met Asn Thr Tyr Lys Val Glu Arg Phe Glu Lys Val Phe Ser Ser
                 170                 175                 180

 Glu Arg Leu Phe Ser Trp Lys Gly Ile Asn Phe Val Met Val Asn
                 185                 190                 195

 Ser Val Ala Leu Asn Gly Asp Gly Cys Gly Ile Cys Ser Glu Thr
                 200                 205                 210

 Glu Ala Glu Leu Ile Glu Val Ser His Arg Leu Asn Cys Ser Arg
                 215                 220                 225

 Glu Ala Arg Gly Ser Ser Arg Cys Gly Pro Gly Pro Leu Leu Pro
                 230                 235                 240

 Thr Ser Ala Pro Val Leu Leu Gln His Tyr Pro Leu Tyr Arg Arg
                 245                 250                 255

 Ser Asp Ala Asn Cys Ser Gly Glu Asp Ala Ala Pro Ala Glu Glu
                 260                 265                 270

 Arg Asp Ile Pro Phe Lys Glu Asn Tyr Asp Val Leu Ser Arg Glu
                 275                 280                 285

 Ala Ser Gln Lys Leu Leu Trp Trp Leu Gln Pro Arg Leu Val Leu
                 290                 295                 300

 Ser Gly His Thr His Ser Ala Cys Glu Val His His Gly Gly Arg
                 305                 310                 315

 Val Pro Glu Leu Ser Val Pro Ser Phe Ser Trp Arg Asn Arg Asn
                 320                 325                 330

 Asn Pro Ser Phe Ile Met Gly Ser Ile Thr Pro Thr Asp Tyr Thr
                 335                 340                 345

 Leu Ser Lys Cys Tyr Leu Pro Arg Glu Asp Val Val Leu Ile Ile
                 350                 355                 360

 Tyr Cys Gly Glu Val Gly Phe Leu Val Val Leu Thr Leu Thr His
                 365                 370                 375

 Phe Gly Leu Leu Ala Ser Pro Phe Leu Ser Gly Leu Asn Leu Leu
                 380                 385                 390

 Gly Lys Arg Lys Thr Arg
                 395

<210> 2830
<211> 3860
<212> DNA
<213> Homo sapien

<400> 2830
 gtgaacgggc agaagcaggg ccatgcccaa gccaccccca agatccccct 50

 gaacctgcac ctccatcacg acccattcag gagcctccag gagcccagac 100

 accagccccc caccatgggc agcaaggagc gcttccactg gcagagccac 150

 aacgtgaagc agagcggcgt ggatgacatg gtgcttcttc cccagatcac 200

 cgaagacgcc attgccgcca acctccggaa gcgcttcatg gacgactaca 250

 tcttcaccta catcggctct gtgctcatct ctgtaaaccc cttcaagcag 300

 atgccctact tcaccgaccg tgagatcgac ctctatcagg gcgcggccca 350

 gtatgagaat cccccgcaca tctacgccct cacggacaac atgtaccgga 400

 acatgcttat cgactgtgag aaccagtgtg tcatcattag tggagagagt 450

 ggagctggga agacagtggc agccaaatat atcatgggct acatctccaa 500

 ggtgtctggc ggaggcgaga aggtccagca cgtcaaagat atcatcctgc 550

 agtccaaccc gctgctcgag gccttcggca acgccaagac tgtgcgcaac 600

 aacaattcca gccgctttgg caagtacttt gagatccagt tcagccgagg 650

 tggggagcca gatgggggca agatctccaa cttcttgctg gagaagtccc 700

 gcgtggtcat gcaaaatgaa aatgagagga acttccacat ctactaccag 750

 ctgctggaag gggcctccca ggagcaaagg cagaacctgg gcctcatgac 800

 accggactac tattactacc tcaaccaatc ggacacctac caggtggacg 850

 gcacggacga cagaagcgac tttggtgaga ctctgagtgc tatgcaggtt 900

 attgggatcc cgcccagcat ccagcagctg gtcctgcagc tcgtggcggg 950

 gatcttgcac ctggggaaca tcagtttctg tgaagacggg aattacgccc 1000

 gagtggagag tgtggacctc ctggcctttc ccgcctacct gctgggcatt 1050

 gacagcgggc gactgcagga gaagctgacc agccgcaaga tggacagccg 1100

 ctggggcggg cgcagcgagt ccatcaatgt gaccctcaac gtggagcagg 1150

 cagcctacac ccgtgatgcc ctggccaagg ggctctatgc ccgcctcttc 1200

 gacttcctcg tggaggccat caaccgtgct atgcagaaac cccaggaaga 1250

 gtacagcatc ggtgtgctgg acatttacgg cttcgagatc ttccagaaaa 1300

 atggcttcga gcagttttgc atcaacttcg tcaatgagaa gctgcagcaa 1350

 atctttatcg aacttaccct gaaggccgag caggaggagt atgtgcagga 1400

 aggcatccgc tggactccaa tccagtactt caacaacaag gtcgtctgtg 1450

 acctcatcga aaacaagctg agccccccag gcatcatgag cgtcttggac 1500

 gacgtgtgcg ccaccatgca cgccacgggc gggggagcag accagacact 1550

 gctgcagaag ctgcaggcgg ctgtggggac ccacgagcat ttcaacagct 1600

 ggagcgccgg cttcgtcatc caccactacg ctggcaaggt ctcctacgac 1650

 gtcagcggct tctgcgagag gaaccgagac gttctcttct ccgacctcat 1700

 agagctgatg cagaccagtg agcaggcctt cctccggatg ctcttccccg 1750

 agaagctgga tggagacaag aaggggcgcc ccagcaccgc cggctccaag 1800

 atcaagaaac aagccaacga cctggtggcc acactgatga ggtgcacacc 1850

 ccactacatc cgctgcatca aacccaacga gaccaagagg ccccgagact 1900

 gggaggagaa cagagtcaag caccaggtgg aatacctggg cctgaaggag 1950

 aacatcaggg tgcgcagagc cggcttcgcc taccgccgcc agttcgccaa 2000

 attcctgcag aggtatgcca ttctgacccc cgagacgtgg ccgcggtggc 2050

 gtggggacga acgccagggc gtccagcacc tgcttcgggc ggtcaacatg 2100

 gagcccgacc agtaccagat ggggagcacc aaggtctttg tcaagaaccc 2150

 agagtcgctt ttcctcctgg aggaggtgcg agagcgaaag ttcgatggct 2200

 ttgcccgaac catccagaag gcctggcggc gccacgtggc tgtccggaag 2250

 tacgaggaga tgcgggagga agcttccaac atcctgctga acaagaagga 2300

 gcggaggcgc aacagcatca atcggaactt cgtcggggac tacctggggc 2350

 tggaggagcg gcccgagctg cgtcagttcc tgggcaagag ggagcgggtg 2400

 gacttcgccg attcggtcac caagtacgac cgccgcttca agcccatcaa 2450

 gcgggacttg atcctgacgc ccaagtgtgt gtatgtgatt gggcgagaga 2500

 aagtgaagaa gggacctgag aagggccagg tgtgtgaagt cttgaagaag 2550

 aaagtggaca tccaggctct gcggggagtc tccctcagca cgcgacagga 2600

 cgacttcttc atcctccaag aggatgccgc cgacagcttc ctggagagcg 2650

 tcttcaagac cgagtttgtc agccttctgt gcaagcgctt cgaggaggcg 2700

 acgcggaggc ccctgcccct caccttcagc gacacactac agtttcgggt 2750

 gaagaaggag ggctggggcg gtggcggcac ccgcagcgtc accttctccc 2800

 gcggcttcgg cgacttggca gtgctcaagg ttggcggtcg gaccctcacg 2850

 gtcagcgtgg gcgatgggct gcccaagagc tccaagccta cgcggaaggg 2900

 aatggccaag ggaaaacctc ggaggtcgtc ccaagcccct acccgggcgg 2950

 cccctgcgcc ccccagaggc atggatcgca atggggtgcc cccctctgcc 3000

 agagggggcc ccctgcccct ggagatcatg tctggagggg gcacccacag 3050

 gcctccccgg ggccctccgt ccacatccct gggagccagc agacgacccc 3100

 gggcacgtcc gccctcagag cacaacacag aattcctcaa cgtgcctgac 3150

 cagggcatgg ccggcatgca gaggaagcgc agcgtggggc aacggccagt 3200

 gcctggtgtg ggccgaccca agccccagcc tcggacacat ggtcccaggt 3250

 gccgggccct ataccagtac gtgggccaag atgtggacga gctgagcttc 3300

 aacgtgaacg aggtcattga gatcctcatg gaagatccct cgggctggtg 3350

 gaagggccgg cttcacggcc aggagggcct tttcccagga aactacgtgg 3400

 agaagatctg agctgggccc tgggatactg ccttctcttt cgcccgccta 3450

 tctgcctgcc ggcctggtgg ggagccaggc cctgccaatg agagcctcgt 3500

 ttacctgggc tgcaatagcc taaaagtcca gtcctttggc ctccagtcct 3550

 gcccaggccc tgggtcacca ggtcactgct gcagcccccg cccctgggcc 3600

 ctggtcttcc tccaacatca cacctgctgc ccattctcca tttctgtgtg 3650

 tgtcaaaggg gactaacagc agaatctacc tcccaactgc catgtgatta 3700

 agaaatgggt cttgagtcct gtgctgttgg caaagtgcca ggcacagttg 3750

 gggagggggg ggtccttaac aagcgtgact ttgctcattc tgtcatcact 3800

 aaggcaataa acctttgcca ggtgaaaaaa aaaaaaaaaa aaaaaaaaaa 3850

 aaaaaaaaaa 3860

<210> 2831
<211> 1098
<212> PRT
<213> Homo sapien

<400> 2831
 Met Gly Ser Lys Glu Arg Phe His Trp Gln Ser His Asn Val Lys
   1               5                  10                  15

 Gln Ser Gly Val Asp Asp Met Val Leu Leu Pro Gln Ile Thr Glu
                  20                  25                  30

 Asp Ala Ile Ala Ala Asn Leu Arg Lys Arg Phe Met Asp Asp Tyr
                  35                  40                  45

 Ile Phe Thr Tyr Ile Gly Ser Val Leu Ile Ser Val Asn Pro Phe
                  50                  55                  60

 Lys Gln Met Pro Tyr Phe Thr Asp Arg Glu Ile Asp Leu Tyr Gln
                  65                  70                  75

 Gly Ala Ala Gln Tyr Glu Asn Pro Pro His Ile Tyr Ala Leu Thr
                  80                  85                  90

 Asp Asn Met Tyr Arg Asn Met Leu Ile Asp Cys Glu Asn Gln Cys
                  95                 100                 105

 Val Ile Ile Ser Gly Glu Ser Gly Ala Gly Lys Thr Val Ala Ala
                 110                 115                 120

 Lys Tyr Ile Met Gly Tyr Ile Ser Lys Val Ser Gly Gly Gly Glu
                 125                 130                 135

 Lys Val Gln His Val Lys Asp Ile Ile Leu Gln Ser Asn Pro Leu
                 140                 145                 150

 Leu Glu Ala Phe Gly Asn Ala Lys Thr Val Arg Asn Asn Asn Ser
                 155                 160                 165

 Ser Arg Phe Gly Lys Tyr Phe Glu Ile Gln Phe Ser Arg Gly Gly
                 170                 175                 180

 Glu Pro Asp Gly Gly Lys Ile Ser Asn Phe Leu Leu Glu Lys Ser
                 185                 190                 195

 Arg Val Val Met Gln Asn Glu Asn Glu Arg Asn Phe His Ile Tyr
                 200                 205                 210

 Tyr Gln Leu Leu Glu Gly Ala Ser Gln Glu Gln Arg Gln Asn Leu
                 215                 220                 225

 Gly Leu Met Thr Pro Asp Tyr Tyr Tyr Tyr Leu Asn Gln Ser Asp
                 230                 235                 240

 Thr Tyr Gln Val Asp Gly Thr Asp Asp Arg Ser Asp Phe Gly Glu
                 245                 250                 255

 Thr Leu Ser Ala Met Gln Val Ile Gly Ile Pro Pro Ser Ile Gln
                 260                 265                 270

 Gln Leu Val Leu Gln Leu Val Ala Gly Ile Leu His Leu Gly Asn
                 275                 280                 285

 Ile Ser Phe Cys Glu Asp Gly Asn Tyr Ala Arg Val Glu Ser Val
                 290                 295                 300

 Asp Leu Leu Ala Phe Pro Ala Tyr Leu Leu Gly Ile Asp Ser Gly
                 305                 310                 315

 Arg Leu Gln Glu Lys Leu Thr Ser Arg Lys Met Asp Ser Arg Trp
                 320                 325                 330

 Gly Gly Arg Ser Glu Ser Ile Asn Val Thr Leu Asn Val Glu Gln
                 335                 340                 345

 Ala Ala Tyr Thr Arg Asp Ala Leu Ala Lys Gly Leu Tyr Ala Arg
                 350                 355                 360

 Leu Phe Asp Phe Leu Val Glu Ala Ile Asn Arg Ala Met Gln Lys
                 365                 370                 375

 Pro Gln Glu Glu Tyr Ser Ile Gly Val Leu Asp Ile Tyr Gly Phe
                 380                 385                 390

 Glu Ile Phe Gln Lys Asn Gly Phe Glu Gln Phe Cys Ile Asn Phe
                 395                 400                 405

 Val Asn Glu Lys Leu Gln Gln Ile Phe Ile Glu Leu Thr Leu Lys
                 410                 415                 420

 Ala Glu Gln Glu Glu Tyr Val Gln Glu Gly Ile Arg Trp Thr Pro
                 425                 430                 435

 Ile Gln Tyr Phe Asn Asn Lys Val Val Cys Asp Leu Ile Glu Asn
                 440                 445                 450

 Lys Leu Ser Pro Pro Gly Ile Met Ser Val Leu Asp Asp Val Cys
                 455                 460                 465

 Ala Thr Met His Ala Thr Gly Gly Gly Ala Asp Gln Thr Leu Leu
                 470                 475                 480

 Gln Lys Leu Gln Ala Ala Val Gly Thr His Glu His Phe Asn Ser
                 485                 490                 495

 Trp Ser Ala Gly Phe Val Ile His His Tyr Ala Gly Lys Val Ser
                 500                 505                 510

 Tyr Asp Val Ser Gly Phe Cys Glu Arg Asn Arg Asp Val Leu Phe
                 515                 520                 525

 Ser Asp Leu Ile Glu Leu Met Gln Thr Ser Glu Gln Ala Phe Leu
                 530                 535                 540

 Arg Met Leu Phe Pro Glu Lys Leu Asp Gly Asp Lys Lys Gly Arg
                 545                 550                 555

 Pro Ser Thr Ala Gly Ser Lys Ile Lys Lys Gln Ala Asn Asp Leu
                 560                 565                 570

 Val Ala Thr Leu Met Arg Cys Thr Pro His Tyr Ile Arg Cys Ile
                 575                 580                 585

 Lys Pro Asn Glu Thr Lys Arg Pro Arg Asp Trp Glu Glu Asn Arg
                 590                 595                 600

 Val Lys His Gln Val Glu Tyr Leu Gly Leu Lys Glu Asn Ile Arg
                 605                 610                 615

 Val Arg Arg Ala Gly Phe Ala Tyr Arg Arg Gln Phe Ala Lys Phe
                 620                 625                 630

 Leu Gln Arg Tyr Ala Ile Leu Thr Pro Glu Thr Trp Pro Arg Trp
                 635                 640                 645

 Arg Gly Asp Glu Arg Gln Gly Val Gln His Leu Leu Arg Ala Val
                 650                 655                 660

 Asn Met Glu Pro Asp Gln Tyr Gln Met Gly Ser Thr Lys Val Phe
                 665                 670                 675

 Val Lys Asn Pro Glu Ser Leu Phe Leu Leu Glu Glu Val Arg Glu
                 680                 685                 690

 Arg Lys Phe Asp Gly Phe Ala Arg Thr Ile Gln Lys Ala Trp Arg
                 695                 700                 705

 Arg His Val Ala Val Arg Lys Tyr Glu Glu Met Arg Glu Glu Ala
                 710                 715                 720

 Ser Asn Ile Leu Leu Asn Lys Lys Glu Arg Arg Arg Asn Ser Ile
                 725                 730                 735

 Asn Arg Asn Phe Val Gly Asp Tyr Leu Gly Leu Glu Glu Arg Pro
                 740                 745                 750

 Glu Leu Arg Gln Phe Leu Gly Lys Arg Glu Arg Val Asp Phe Ala
                 755                 760                 765

 Asp Ser Val Thr Lys Tyr Asp Arg Arg Phe Lys Pro Ile Lys Arg
                 770                 775                 780

 Asp Leu Ile Leu Thr Pro Lys Cys Val Tyr Val Ile Gly Arg Glu
                 785                 790                 795

 Lys Val Lys Lys Gly Pro Glu Lys Gly Gln Val Cys Glu Val Leu
                 800                 805                 810

 Lys Lys Lys Val Asp Ile Gln Ala Leu Arg Gly Val Ser Leu Ser
                 815                 820                 825

 Thr Arg Gln Asp Asp Phe Phe Ile Leu Gln Glu Asp Ala Ala Asp
                 830                 835                 840

 Ser Phe Leu Glu Ser Val Phe Lys Thr Glu Phe Val Ser Leu Leu
                 845                 850                 855

 Cys Lys Arg Phe Glu Glu Ala Thr Arg Arg Pro Leu Pro Leu Thr
                 860                 865                 870

 Phe Ser Asp Thr Leu Gln Phe Arg Val Lys Lys Glu Gly Trp Gly
                 875                 880                 885

 Gly Gly Gly Thr Arg Ser Val Thr Phe Ser Arg Gly Phe Gly Asp
                 890                 895                 900

 Leu Ala Val Leu Lys Val Gly Gly Arg Thr Leu Thr Val Ser Val
                 905                 910                 915

 Gly Asp Gly Leu Pro Lys Ser Ser Lys Pro Thr Arg Lys Gly Met
                 920                 925                 930

 Ala Lys Gly Lys Pro Arg Arg Ser Ser Gln Ala Pro Thr Arg Ala
                 935                 940                 945

 Ala Pro Ala Pro Pro Arg Gly Met Asp Arg Asn Gly Val Pro Pro
                 950                 955                 960

 Ser Ala Arg Gly Gly Pro Leu Pro Leu Glu Ile Met Ser Gly Gly
                 965                 970                 975

 Gly Thr His Arg Pro Pro Arg Gly Pro Pro Ser Thr Ser Leu Gly
                 980                 985                 990

 Ala Ser Arg Arg Pro Arg Ala Arg Pro Pro Ser Glu His Asn Thr
                 995                1000                1005

 Glu Phe Leu Asn Val Pro Asp Gln Gly Met Ala Gly Met Gln Arg
                1010                1015                1020

 Lys Arg Ser Val Gly Gln Arg Pro Val Pro Gly Val Gly Arg Pro
                1025                1030                1035

 Lys Pro Gln Pro Arg Thr His Gly Pro Arg Cys Arg Ala Leu Tyr
                1040                1045                1050

 Gln Tyr Val Gly Gln Asp Val Asp Glu Leu Ser Phe Asn Val Asn
                1055                1060                1065

 Glu Val Ile Glu Ile Leu Met Glu Asp Pro Ser Gly Trp Trp Lys
                1070                1075                1080

 Gly Arg Leu His Gly Gln Glu Gly Leu Phe Pro Gly Asn Tyr Val
                1085                1090                1095

 Glu Lys Ile


<210> 2832
<211> 1299
<212> DNA
<213> Homo sapien

<400> 2832
 ggcacgaggg cggcggcggc ggtagaggcg gcggcggcgg cggcagcggg 50

 ctcggaggca gcggttgggc tcgcggcgag cggacggggt cgagtcagtg 100

 cgttcgcgcg agttggaatc gaagcctctt aaaatggcag atgacttgga 150

 cttcgagaca ggagatgcag gggcctcagc caccttccca atgcagtgct 200

 cagcattacg taagaatggc tttgtggtgc tcaaaggccg gccatgtaag 250

 atcgtcgaga tgtctacttc gaagactggc aagcacggcc acgccaaggt 300

 ccatctggtt ggtattgaca tctttactgg gaagaaatat gaagatatct 350

 gcccgtcaac tcataatatg gatgtcccca acatcaaaag gaatgacttc 400

 cagctgattg gcatccagga tgggtaccta tcactgctcc aggacagcgg 450

 ggaggtacga gaggaccttc gtctccctga gggagacctt ggcaaggaga 500

 ttgagcagaa gtacgactgt ggagaagaga tcctgatcac ggtgctgtct 550

 gccatgacag aggaggcagc tgttgcaatc aaggccatgg caaaataact 600

 ggctcccagg atggcggtgg tggcagcagt gatcctctga acctgcagag 650

 gccccctccc cgagcctggc ctggctctgg cccggtccta agctggactc 700

 ctcctacaca atttatttga cgttttattt tggttttccc caccccctca 750

 atctgtcggg gagcccctgc ccttcaccta gctcccttgg ccaggagcga 800

 gcgaagctgt ggccttggtg aagctgccct cctcttctcc cctcacacta 850

 cagccctggt gggggagaag ggggtgggtg ctgcttgtgg tttagtcttt 900

 tttttttttt tttttttttt tttaaattca atctggaatc agaaagcggt 950

 ggattctggc aaatggtcct tgtgccctcc ccactcatcc ctggtctggt 1000

 cccctgttgc ccatagccct ttaccctgag caccacccca acagactggg 1050

 gaccagcccc ctcgcctgcc tgtgtctctc cccaaacccc tttagatggg 1100

 gagggaagag gaggagaggg gaggggacct gccccctcct caggcatctg 1150

 ggagggccct gcccccatgg gctttaccct tccctgcggg ctctctcccc 1200

 gacacatttg ttaaaatcaa acctgaataa aactacaagt ttaatatgaa 1250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1299

<210> 2833
<211> 154
<212> PRT
<213> Homo sapien

<400> 2833
 Met Ala Asp Asp Leu Asp Phe Glu Thr Gly Asp Ala Gly Ala Ser
   1               5                  10                  15

 Ala Thr Phe Pro Met Gln Cys Ser Ala Leu Arg Lys Asn Gly Phe
                  20                  25                  30

 Val Val Leu Lys Gly Arg Pro Cys Lys Ile Val Glu Met Ser Thr
                  35                  40                  45

 Ser Lys Thr Gly Lys His Gly His Ala Lys Val His Leu Val Gly
                  50                  55                  60

 Ile Asp Ile Phe Thr Gly Lys Lys Tyr Glu Asp Ile Cys Pro Ser
                  65                  70                  75

 Thr His Asn Met Asp Val Pro Asn Ile Lys Arg Asn Asp Phe Gln
                  80                  85                  90

 Leu Ile Gly Ile Gln Asp Gly Tyr Leu Ser Leu Leu Gln Asp Ser
                  95                 100                 105

 Gly Glu Val Arg Glu Asp Leu Arg Leu Pro Glu Gly Asp Leu Gly
                 110                 115                 120

 Lys Glu Ile Glu Gln Lys Tyr Asp Cys Gly Glu Glu Ile Leu Ile
                 125                 130                 135

 Thr Val Leu Ser Ala Met Thr Glu Glu Ala Ala Val Ala Ile Lys
                 140                 145                 150

 Ala Met Ala Lys


<210> 2834
<211> 2853
<212> DNA
<213> Homo sapien

<400> 2834
 gctctgctcc aggcatctgc cacaatgtgg gtgcttacac ctgctgcttt 50

 tgctgggaag ctcttgagtg tgttcaggca acctctgagc tctctgtgga 100

 ggagcctggt cccgctgttc tgctggctga gggcaacctt ctggctgcta 150

 gctaccaaga ggagaaagca gcagctggtc ctgagagggc cagatgagac 200

 caaagaggag gaagaggacc ctcctctgcc caccacccca accagcgtca 250

 actatcactt cactcgccag tgcaactaca aatgcggctt ctgtttccac 300

 acagccaaaa catcctttgt gctgcccctt gaggaagcaa agagaggatt 350

 gcttttgctt aaggaagctg gtatggagaa gatcaacttt tcaggtggag 400

 agccatttct tcaagaccgg ggagaatacc tgggcaagtt ggtgaggttc 450

 tgcaaagtag agttgcggct gcccagcgtg agcatcgtga gcaatggaag 500

 cctgatccgg gagaggtggt tccagaatta tggtgagtat ttggacattc 550

 tcgctatctc ctgtgacagc tttgacgagg aagtcaatgt ccttattggc 600

 cgtggccaag gaaagaagaa ccatgtggaa aaccttcaaa agctgaggag 650

 gtggtgtagg gattatagag tcgctttcaa gataaattct gtcattaatc 700

 gtttcaacgt ggaagaggac atgacggaac agatcaaagc actaaaccct 750

 gtccgctgga aagtgttcca gtgcctctta attgagggtg agaattgtgg 800

 agaagatgct ctaagagaag cagaaagatt tgttattggt gatgaagaat 850

 ttgaaagatt cttggagcgc cacaaagaag tgtcctgctt ggtgcctgaa 900

 tctaaccaga agatgaaaga ctcctacctt attctggatg aatatatgcg 950

 ctttctgaac tgtagaaagg gacggaagga cccttccaag tccatcctgg 1000

 atgttggtgt agaagaagct ataaaattca gtggatttga tgaaaagatg 1050

 tttctgaagc gaggaggaaa atacatatgg agtaaggctg atctgaagct 1100

 ggattggtag agcggaaagt ggaacgagac ttcaacacac cagtgggaaa 1150

 actcctagag taactgccat tgtctgcaat actatcccgt tggtatttcc 1200

 cagtggctga aaacctgatt ttctgctgca cgtggcatct gattacctgt 1250

 ggtcactgaa cacacgaata acttggatag caaatcctga gacaatggaa 1300

 aaccattaac tttacttcat tggcttataa ccttgttgtt attgaaacag 1350

 cacttctgtt tttgagtttg ttttagctaa aaagaaggaa tacacacagg 1400

 aataatgacc ccaaaaatgc ttagataagg cccctataca caggacctga 1450

 catttagctc aatgatgcgt ttgtaagaaa taagctctag tgatatctgt 1500

 gggggcaaaa tttaatttgg atttgatttt ttaaaacaat gtttactgcg 1550

 atttctatat ttccattttg aaactatttc ttgttccagg tttgttcatt 1600

 tgacagagtc agtatttttt gccaaatatc cagataacca gttttcacat 1650

 ctgagacatt acaaagtatc tgcctcaatt atttctgctg gttataatgc 1700

 tttttttttt ttgcctttat gccattgcag tcttgtactt tttactgtga 1750

 tgtacagaaa tagtcaacag atgtttccaa gaacatatga tatgataatc 1800

 ctaccaattt tcaagaagtc tctagaaaga gataacacat ggaaagacgg 1850

 cgtggtgcag cccagcccac ggtgcctgtt ccatgaatgc tggctaccta 1900

 tgtgtgtggt acctgttgtg tccctttctc ttcaaagatc cctgagcaaa 1950

 acaaagatac gctttccatt tgatgatgga gttgacatgg aggcagtgct 2000

 tgcattgctt tgttcgccta tcatctggcc acatgaggct gtcaagcaaa 2050

 agaataggag tgtagttgag tagctggttg gccctacatt tctgagaagt 2100

 gacgttacac tgggttggca taagatatcc taaaatcacg ctggaacctt 2150

 gggcaaggaa gaatgtgagc aagagtagag agagtgcctg gatttcatgt 2200

 cagtgaagcc atgtcaccat atcatatttt tgaatgaact ctgagtcagt 2250

 tgaaataggg taccatctag gtcagtttaa gaagagtcag ctcagagaaa 2300

 gcaagcataa gggaaaatgt cacgtaaact agatcaggga acaaaatcct 2350

 ctccttgtgg aaatatccca tgcagtttgt tgatacaact tagtatctta 2400

 ttgcctaaaa aaaaatttct tatcattgtt tcaaaaaagc aaaatcatgg 2450

 aaaatttttg ttgtccaggc aaataaaagg tcattttaat ttaaaaaaaa 2500

 aaaaaaaaaa aaaaaaaaaa aaaaggccaa ggaaaaaaaa tattcctact 2550

 taaattttaa gtctataatt caatttaaat atgtgtgtgt ctcatccagg 2600

 ataggatagg ttgtcttcta ttttccattt tacctattta ctttttttgt 2650

 aagaaaagag aagaatgaat tctaaagatg ttccccatgg gttttgattg 2700

 tgtctaagct atgatgacct tcatataatc agcataaaca taaaacaaat 2750

 tttttactta acatgagtgc actttactaa tcctcatggc acagtggctc 2800

 acgcctgtaa tcccagcact tggggaggac aatgtggggt ggatcacgag 2850

 gtc 2853

<210> 2835
<211> 361
<212> PRT
<213> Homo sapien

<400> 2835
 Met Trp Val Leu Thr Pro Ala Ala Phe Ala Gly Lys Leu Leu Ser
   1               5                  10                  15

 Val Phe Arg Gln Pro Leu Ser Ser Leu Trp Arg Ser Leu Val Pro
                  20                  25                  30

 Leu Phe Cys Trp Leu Arg Ala Thr Phe Trp Leu Leu Ala Thr Lys
                  35                  40                  45

 Arg Arg Lys Gln Gln Leu Val Leu Arg Gly Pro Asp Glu Thr Lys
                  50                  55                  60

 Glu Glu Glu Glu Asp Pro Pro Leu Pro Thr Thr Pro Thr Ser Val
                  65                  70                  75

 Asn Tyr His Phe Thr Arg Gln Cys Asn Tyr Lys Cys Gly Phe Cys
                  80                  85                  90

 Phe His Thr Ala Lys Thr Ser Phe Val Leu Pro Leu Glu Glu Ala
                  95                 100                 105

 Lys Arg Gly Leu Leu Leu Leu Lys Glu Ala Gly Met Glu Lys Ile
                 110                 115                 120

 Asn Phe Ser Gly Gly Glu Pro Phe Leu Gln Asp Arg Gly Glu Tyr
                 125                 130                 135

 Leu Gly Lys Leu Val Arg Phe Cys Lys Val Glu Leu Arg Leu Pro
                 140                 145                 150

 Ser Val Ser Ile Val Ser Asn Gly Ser Leu Ile Arg Glu Arg Trp
                 155                 160                 165

 Phe Gln Asn Tyr Gly Glu Tyr Leu Asp Ile Leu Ala Ile Ser Cys
                 170                 175                 180

 Asp Ser Phe Asp Glu Glu Val Asn Val Leu Ile Gly Arg Gly Gln
                 185                 190                 195

 Gly Lys Lys Asn His Val Glu Asn Leu Gln Lys Leu Arg Arg Trp
                 200                 205                 210

 Cys Arg Asp Tyr Arg Val Ala Phe Lys Ile Asn Ser Val Ile Asn
                 215                 220                 225

 Arg Phe Asn Val Glu Glu Asp Met Thr Glu Gln Ile Lys Ala Leu
                 230                 235                 240

 Asn Pro Val Arg Trp Lys Val Phe Gln Cys Leu Leu Ile Glu Gly
                 245                 250                 255

 Glu Asn Cys Gly Glu Asp Ala Leu Arg Glu Ala Glu Arg Phe Val
                 260                 265                 270

 Ile Gly Asp Glu Glu Phe Glu Arg Phe Leu Glu Arg His Lys Glu
                 275                 280                 285

 Val Ser Cys Leu Val Pro Glu Ser Asn Gln Lys Met Lys Asp Ser
                 290                 295                 300

 Tyr Leu Ile Leu Asp Glu Tyr Met Arg Phe Leu Asn Cys Arg Lys
                 305                 310                 315

 Gly Arg Lys Asp Pro Ser Lys Ser Ile Leu Asp Val Gly Val Glu
                 320                 325                 330

 Glu Ala Ile Lys Phe Ser Gly Phe Asp Glu Lys Met Phe Leu Lys
                 335                 340                 345

 Arg Gly Gly Lys Tyr Ile Trp Ser Lys Ala Asp Leu Lys Leu Asp
                 350                 355                 360

 Trp


<210> 2836
<211> 6161
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3745-3779
<223> Unknown base

<400> 2836
 cggcgcctcc gcggagaggt ccggtccgaa tatccctccg ccttcctccc 50

 tccctcgctc cctccctgcg cgccgcctct cactcacagc ctcccttcct 100

 tctttctccc tccgcctccc gagcaccagc gcgctctgag ctgcccccag 150

 ggtccctccc ccgccgccag cagcccattt ggagggagga agtaagggaa 200

 gaggagagga aggggagccg gaccgactac ccagacagag ccggtgaatg 250

 ggtttgtggt gacccccgcc ccccacccca ccctcccttc ccacccgacc 300

 cccaaccccc atccccagtt cgagccgccg cccgaaaggc cgggccgtcg 350

 tcttaggagg agtcgccgcc gccgcacctc cgccatggag ctgatcacca 400

 ttctcgagaa gaccgtgtct cccgatcggc tggagctgga agcggcgcag 450

 aagttcctgg agcgtgcggc cgtggagaac ctgcccactt tccttgtgga 500

 actgtccaga gtgctggcaa atccaggaaa cagtcaggtt gccagagttg 550

 cagctggtct acaaatcaag aactctttga catctaaaga tccagatatc 600

 aaggcacaat atcagcagag gtggcttgct attgatgcta atgctcgacg 650

 agaagtcaag aactatgttt tgcagacatt gggtacagaa acttaccggc 700

 ctagttctgc ctcacagtgt gtggctggta ttgcttgtgc agagatccca 750

 gtaaaccagt ggccagaact cattcctcag ctggtggcca atgtcacaaa 800

 ccccaacagc acagagcaca tgaaggagtc gacattggaa gccatcggtt 850

 atatttgcca agatatagac ccagagcagc tacaagataa atccaatgag 900

 attctgactg ccataatcca ggggatgagg aaagaagagc ctagtaataa 950

 tgtgaagcta gctgctacga atgcactcct gaactcattg gagttcacca 1000

 aagcaaactt tgataaagag tctgaaaggc actttattat gcaggtggtc 1050

 tgtgaagcca cacagtgtcc agatacgagg gtacgagtgg ctgctttaca 1100

 gaatctggtg aagataatgt ccttatatta tcagtacatg gagacatata 1150

 tgggtcctgc tctttttgca atcacaatcg aagcaatgaa aagtgacatt 1200

 gatgaggtgg ctttacaagg gatagaattc tggtccaatg tctgtgatga 1250

 ggaaatggat ttggccattg aagcttcaga ggcagcagaa caaggacggc 1300

 cccctgagca caccagcaag ttttatgcga agggagcact acagtatctg 1350

 gttccaatcc tcacacagac actaactaaa caggacgaaa atgatgatga 1400

 cgatgactgg aacccctgca aagcagcagg ggtgtgcctc atgcttctgg 1450

 ccacctgctg tgaagatgac attgtcccac atgtcctccc cttcattaaa 1500

 gaacacatca agaacccaga ttggcggtac cgggatgcag cagtgatggc 1550

 ttttggttgt atcttggaag gaccagagcc cagtcagctc aaaccactag 1600

 ttatacaggc tatgcccacc ctaatagaat taatgaaaga ccccagtgta 1650

 gttgttcgag atacagctgc atggactgta ggcagaattt gtgagctgct 1700

 tcctgaagct gccatcaatg atgtctactt ggctcccctg ctacagtgtc 1750

 tgattgaggg tctcagtgct gaacccagag tggcttcaaa tgtgtgctgg 1800

 gctttctcca gtctggctga agctgcttat gaagctgcag acgttgctga 1850

 tgatcaggaa gaaccagcta cttactgctt atcttcttca tttgaactca 1900

 tagttcagaa gctcctagag actacagaca gacctgatgg acaccagaac 1950

 aacctgagga gttctgcata tgaatctctg atggaaattg tgaaaaacag 2000

 tgccaaggat tgttatcctg ctgtccagaa aacgactttg gtcatcatgg 2050

 aacgactgca acaggttctt cagatggagt cacatatcca gagcacatcc 2100

 gatagaatcc agttcaatga ccttcagtct ttactctgtg caactcttca 2150

 gaatgttctt cggaaagtgc aacatcaaga tgctttgcag atctctgatg 2200

 tggttatggc ctccctgtta aggatgttcc aaagcacagc tgggtctggg 2250

 ggagtacaag aggatgccct gatggcagtt agcacactgg tggaagtgtt 2300

 gggtggtgaa ttcctcaagt acatggaggc ctttaaaccc ttcctgggca 2350

 ttggattaaa aaattatgct gaataccagg tttgtttggc agctgtgggc 2400

 ttagtgggag acttgtgccg tgccctgcaa tccaacatca tacctttctg 2450

 tgacgaggtg atgcagctgc ttctggaaaa tttggggaat gagaacgtcc 2500

 acaggtctgt gaagccgcag attctgtcag tgtttggtga tattgccctt 2550

 gctattggag gagagtttaa aaaatactta gaggttgtat tgaatactct 2600

 tcagcaggcc tcccaagccc aggtggacaa gtcagactat gacatggtgg 2650

 attatctgaa tgagctaagg gaaagctgct tggaagccta tactggaatc 2700

 gtccagggat taaaggggga tcaggagaac gtacacccgg atgtgatgct 2750

 ggtacaaccc agagtagaat ttattctgtc tttcattgac cacattgctg 2800

 gagatgagga tcacacagat ggagtagtag cttgtgctgc tggactaata 2850

 ggggacttat gtacagcatt tgggaaggat gtactgaaat tagtagaagc 2900

 taggccaatg atccatgaat tgttaactga agggcggaga tcgaagacta 2950

 acaaagcaaa aacccttgct acatgggcaa caaaagaact gaggaaactg 3000

 aagaaccaag cttgatctgt taccattggg atgataacct gaggaccccc 3050

 actggaaatc tcccatcttt tgaaaaacct ggaagtgagg agtgtgcacg 3100

 gatgctgaat gtttgggaat gagaggatga gtgagtgagg cttgaaaaca 3150

 caccacattg aaaatcctgc cacagcagca gccgcagccg ccaacagcag 3200

 cgctgttagt gagctaagta agcactgact tcgtagaaaa ccataacatc 3250

 ggccatcttg gaaaagagaa aaacaatgga gttacttatt taaaaaaaaa 3300

 gaaagaaagt tatctcttcc caggagaggc tagaagtagc ttttctgtct 3350

 tttggccagt gccgagtgga atgcctggtt tgggggagga ggagggactg 3400

 ggttcagctg tggtgctttg ttgtaaaagg cagcctggcc tttgctactg 3450

 aggagaaaga tggagcctgg gtctcaagcc caccttcgct gtacctttgc 3500

 cacatggtac tgtatgcttg ccagctagaa ggagggtcag ggatttttta 3550

 cagtctgaga atgagtgtgt gtgagtgagg cggtatccac attctcaact 3600

 tcaagtcatt gcagtttctt tttcccagaa aacaaggggt tagatgttgc 3650

 atttcataaa actaaccgaa gttctgtcta ctgatgcagc acaagagatg 3700

 taaaaaaaaa aaaacacaca cacagaggaa agacgctctt taggnnnnnn 3750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnng ttttttttac tctagggaaa 3800

 acactgacga atggtcagag ctcctatcct gatcttttca tcaaggcgcc 3850

 tttcctaata atatggttca actgtgaatg tagaagtggg ggggaggggg 3900

 gagaaaaaga aaactctggc gttagaggat atagaaaaat ataagtacaa 3950

 ttgttacaaa taacgcagac ttcaaaaaca aaaaaatcac aacccaaaca 4000

 aaccaaaatt taaatgatca gaattggcag cacaaagaaa acgccctctc 4050

 ctgacttgta ttgtggcagt ctgaacgccc ccagaaaatt gtgccaaaga 4100

 gtttagaaaa ataaatatac aataaaagta aacacataca cacaaaacag 4150

 caaacttcag gtaactattt tggattgcaa acaggataaa ttaaatgttc 4200

 aaacaatctg ataaaataac catttggaaa ctgcttggcc ttctgttctt 4250

 ttatttgatt gactacaatg cggtattggt ctcttgctgc acttcaaaag 4300

 caaccaacaa aacaaaaaca aaaaaaagtg tgtgtgtgtg aatacacaca 4350

 cacactaact agaagtcttg tgatgaaaat ggcacttgga aaaggtttta 4400

 tttttccact gaagttgaag gttaataaaa tggtgtcaaa cgtcccctgg 4450

 tcacacactt gaatattttt ttagaagtgt gatgtggtat gattaccata 4500

 aatcagactt aattattttc ccttttacaa gggaacaggg catcctgaat 4550

 tttagagcct ttcagcaata agaagggatg ttggtgagct ttgatcctct 4600

 tttggttttg cagttgttag gagtttttgc tggcattttg aatatgctgc 4650

 tttcagaaaa accaaggaag ttttaaaatt gcttcctggt ccttagagga 4700

 ctaaaaacaa gaccctcatt cccactttca tttccactct agcaaaaact 4750

 gggcttgcgt ttttctccaa ctcctcgttt atatcctccc ttccatgtcc 4800

 aagccttcca ttcctaagtg ggattggctc agttttgccc atccatatgg 4850

 cagcatctct aatagctctt gtacagggta tcagatattg tgccttttgg 4900

 tgccaggttc aaagtcaagt gccgatctat gaaccagtgt acaaaaaaaa 4950

 aaaaaatcca ggtatttgaa ggagagacgc tccattgtga ataaagagct 5000

 cataccagct cctaagccct attaagaaga ggcctggtcc tctaatgcct 5050

 tgtttccatt tcagttgttc tttgagagac agaatgatgt actaaccatt 5100

 cgtgattatt aagatagggt tgggtcaggg cttagggagg gggcagaaat 5150

 attggggata gaaaaaaaat ctgatcattc ctcagtgcta cccatttctg 5200

 tcctgtgtgg gctgcttagc tagacagcag gagaataaag tacaccgaga 5250

 accataatga aaaaaccttc cgtgtgtttt gtcatgtttt gttccaggga 5300

 agcagttgat gagtgctgtt actaatgctt tctcccagat ccattcagtg 5350

 gtggagagga ggaaaatggg ctggttggat gtggtcttgg tgccttgcag 5400

 ttactctgca ctggttatgc atttaattct cctcttttct agttaacctt 5450

 ttgccagtgg gttttccata gtctgggtat ttgtccttat atcagttata 5500

 ccacctaagg caactgggtg caaaatgcat tctgttcact cactgtctgg 5550

 gccttcccca ccctagtctt ggcacattcc ttcaagaatg tagttaccgt 5600

 ctgcttggga agatgtcagt gcaaatgtga agataatggg catcggacta 5650

 ggctttggtt tgccacaagt ggcagctgcc tgtatcaatt acatttatta 5700

 attttgcttt tcatttttcc cagttctcct caccccccct ttgttgaaat 5750

 gttggacttg ctgtcagagg caactgtaat attgccttag ggacttgtgg 5800

 agaaggggaa ttgctcagtg tagtgtttta actttcagaa ccaagcaatc 5850

 tatttactct tacaaatatt taagaagtgt gttagtccaa ctttaagaaa 5900

 aatccaaact catcagcttt tgatagcatc ttggtttttg aaacaacttc 5950

 aatctgtaat tggcattcag aatgcccttg gcatgccagt ctgtgatggc 6000

 atttaagacc tgtaaaacac ttgagcccaa ctcgattaac caaaaccgat 6050

 aaccaccacc tttatcttct aaataaagtc cgctttattt ttaaaaaaaa 6100

 tctatgtcgg gtgcggagaa agaggtaatg aaatggcagg aattcgatat 6150

 gcaagcttat c 6161

<210> 2837
<211> 1004
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3745-3779
<223> Unknown amino acid

<400> 2837
 Ala Pro Pro Arg Arg Gly Pro Val Arg Ile Ser Leu Arg Leu Pro
   1               5                  10                  15

 Pro Ser Leu Ala Pro Ser Leu Arg Ala Ala Ser His Ser Gln Pro
                  20                  25                  30

 Pro Phe Leu Leu Ser Pro Ser Ala Ser Arg Ala Pro Ala Arg Ser
                  35                  40                  45

 Glu Leu Pro Pro Gly Ser Leu Pro Arg Arg Gln Gln Pro Ile Trp
                  50                  55                  60

 Arg Glu Glu Val Arg Glu Glu Glu Arg Lys Gly Ser Arg Thr Asp
                  65                  70                  75

 Tyr Pro Asp Arg Ala Gly Glu Trp Val Cys Gly Asp Thr Pro Ala
                  80                  85                  90

 Pro His Pro Thr Leu Pro Ser His Pro Thr Pro Asn Pro His Pro
                  95                 100                 105

 Gln Phe Glu Pro Pro Pro Glu Arg Pro Gly Arg Arg Leu Arg Arg
                 110                 115                 120

 Ser Arg Arg Arg Arg Thr Ser Ala Met Glu Leu Ile Thr Ile Leu
                 125                 130                 135

 Glu Lys Thr Val Ser Pro Asp Arg Leu Glu Leu Glu Ala Ala Gln
                 140                 145                 150

 Lys Phe Leu Glu Arg Ala Ala Val Glu Asn Leu Pro Thr Phe Leu
                 155                 160                 165

 Val Glu Leu Ser Arg Val Leu Ala Asn Pro Gly Asn Ser Gln Val
                 170                 175                 180

 Ala Arg Val Ala Ala Gly Leu Gln Ile Lys Asn Ser Leu Thr Ser
                 185                 190                 195

 Lys Asp Pro Asp Ile Lys Ala Gln Tyr Gln Gln Arg Trp Leu Ala
                 200                 205                 210

 Ile Asp Ala Asn Ala Arg Arg Glu Val Lys Asn Tyr Val Leu Gln
                 215                 220                 225

 Thr Leu Gly Thr Glu Thr Tyr Arg Pro Ser Ser Ala Ser Gln Cys
                 230                 235                 240

 Val Ala Gly Ile Ala Cys Ala Glu Ile Pro Val Asn Gln Trp Pro
                 245                 250                 255

 Glu Leu Ile Pro Gln Leu Val Ala Asn Val Thr Asn Pro Asn Ser
                 260                 265                 270

 Thr Glu His Met Lys Glu Ser Thr Leu Glu Ala Ile Gly Tyr Ile
                 275                 280                 285

 Cys Gln Asp Ile Asp Pro Glu Gln Leu Gln Asp Lys Ser Asn Glu
                 290                 295                 300

 Ile Leu Thr Ala Ile Ile Gln Gly Met Arg Lys Glu Glu Pro Ser
                 305                 310                 315

 Asn Asn Val Lys Leu Ala Ala Thr Asn Ala Leu Leu Asn Ser Leu
                 320                 325                 330

 Glu Phe Thr Lys Ala Asn Phe Asp Lys Glu Ser Glu Arg His Phe
                 335                 340                 345

 Ile Met Gln Val Val Cys Glu Ala Thr Gln Cys Pro Asp Thr Arg
                 350                 355                 360

 Val Arg Val Ala Ala Leu Gln Asn Leu Val Lys Ile Met Ser Leu
                 365                 370                 375

 Tyr Tyr Gln Tyr Met Glu Thr Tyr Met Gly Pro Ala Leu Phe Ala
                 380                 385                 390

 Ile Thr Ile Glu Ala Met Lys Ser Asp Ile Asp Glu Val Ala Leu
                 395                 400                 405

 Gln Gly Ile Glu Phe Trp Ser Asn Val Cys Asp Glu Glu Met Asp
                 410                 415                 420

 Leu Ala Ile Glu Ala Ser Glu Ala Ala Glu Gln Gly Arg Pro Pro
                 425                 430                 435

 Glu His Thr Ser Lys Phe Tyr Ala Lys Gly Ala Leu Gln Tyr Leu
                 440                 445                 450

 Val Pro Ile Leu Thr Gln Thr Leu Thr Lys Gln Asp Glu Asn Asp
                 455                 460                 465

 Asp Asp Asp Asp Trp Asn Pro Cys Lys Ala Ala Gly Val Cys Leu
                 470                 475                 480

 Met Leu Leu Ala Thr Cys Cys Glu Asp Asp Ile Val Pro His Val
                 485                 490                 495

 Leu Pro Phe Ile Lys Glu His Ile Lys Asn Pro Asp Trp Arg Tyr
                 500                 505                 510

 Arg Asp Ala Ala Val Met Ala Phe Gly Cys Ile Leu Glu Gly Pro
                 515                 520                 525

 Glu Pro Ser Gln Leu Lys Pro Leu Val Ile Gln Ala Met Pro Thr
                 530                 535                 540

 Leu Ile Glu Leu Met Lys Asp Pro Ser Val Val Val Arg Asp Thr
                 545                 550                 555

 Ala Ala Trp Thr Val Gly Arg Ile Cys Glu Leu Leu Pro Glu Ala
                 560                 565                 570

 Ala Ile Asn Asp Val Tyr Leu Ala Pro Leu Leu Gln Cys Leu Ile
                 575                 580                 585

 Glu Gly Leu Ser Ala Glu Pro Arg Val Ala Ser Asn Val Cys Trp
                 590                 595                 600

 Ala Phe Ser Ser Leu Ala Glu Ala Ala Tyr Glu Ala Ala Asp Val
                 605                 610                 615

 Ala Asp Asp Gln Glu Glu Pro Ala Thr Tyr Cys Leu Ser Ser Ser
                 620                 625                 630

 Phe Glu Leu Ile Val Gln Lys Leu Leu Glu Thr Thr Asp Arg Pro
                 635                 640                 645

 Asp Gly His Gln Asn Asn Leu Arg Ser Ser Ala Tyr Glu Ser Leu
                 650                 655                 660

 Met Glu Ile Val Lys Asn Ser Ala Lys Asp Cys Tyr Pro Ala Val
                 665                 670                 675

 Gln Lys Thr Thr Leu Val Ile Met Glu Arg Leu Gln Gln Val Leu
                 680                 685                 690

 Gln Met Glu Ser His Ile Gln Ser Thr Ser Asp Arg Ile Gln Phe
                 695                 700                 705

 Asn Asp Leu Gln Ser Leu Leu Cys Ala Thr Leu Gln Asn Val Leu
                 710                 715                 720

 Arg Lys Val Gln His Gln Asp Ala Leu Gln Ile Ser Asp Val Val
                 725                 730                 735

 Met Ala Ser Leu Leu Arg Met Phe Gln Ser Thr Ala Gly Ser Gly
                 740                 745                 750

 Gly Val Gln Glu Asp Ala Leu Met Ala Val Ser Thr Leu Val Glu
                 755                 760                 765

 Val Leu Gly Gly Glu Phe Leu Lys Tyr Met Glu Ala Phe Lys Pro
                 770                 775                 780

 Phe Leu Gly Ile Gly Leu Lys Asn Tyr Ala Glu Tyr Gln Val Cys
                 785                 790                 795

 Leu Ala Ala Val Gly Leu Val Gly Asp Leu Cys Arg Ala Leu Gln
                 800                 805                 810

 Ser Asn Ile Ile Pro Phe Cys Asp Glu Val Met Gln Leu Leu Leu
                 815                 820                 825

 Glu Asn Leu Gly Asn Glu Asn Val His Arg Ser Val Lys Pro Gln
                 830                 835                 840

 Ile Leu Ser Val Phe Gly Asp Ile Ala Leu Ala Ile Gly Gly Glu
                 845                 850                 855

 Phe Lys Lys Tyr Leu Glu Val Val Leu Asn Thr Leu Gln Gln Ala
                 860                 865                 870

 Ser Gln Ala Gln Val Asp Lys Ser Asp Tyr Asp Met Val Asp Tyr
                 875                 880                 885

 Leu Asn Glu Leu Arg Glu Ser Cys Leu Glu Ala Tyr Thr Gly Ile
                 890                 895                 900

 Val Gln Gly Leu Lys Gly Asp Gln Glu Asn Val His Pro Asp Val
                 905                 910                 915

 Met Leu Val Gln Pro Arg Val Glu Phe Ile Leu Ser Phe Ile Asp
                 920                 925                 930

 His Ile Ala Gly Asp Glu Asp His Thr Asp Gly Val Val Ala Cys
                 935                 940                 945

 Ala Ala Gly Leu Ile Gly Asp Leu Cys Thr Ala Phe Gly Lys Asp
                 950                 955                 960

 Val Leu Lys Leu Val Glu Ala Arg Pro Met Ile His Glu Leu Leu
                 965                 970                 975

 Thr Glu Gly Arg Arg Ser Lys Thr Asn Lys Ala Lys Thr Leu Ala
                 980                 985                 990

 Thr Trp Ala Thr Lys Glu Leu Arg Lys Leu Lys Asn Gln Ala
                 995                1000

<210> 2838
<211> 2688
<212> DNA
<213> Homo sapien

<400> 2838
 ggtcttgctg tgttacctgg gctagttatg tgagtttcta tattagacat 50

 agtctcaagt ttcaggtagg gtttaaagta gagacactgg tcagtatttc 100

 ttttttgggg ggaactagga gagcaggagt agaagtgaga tgttaagatc 150

 ttatggcact aaagacttac tattctgttc ctacatactc tgttaggatc 200

 agatagatgt tatagaaatg ccttttgttt ctcctgccct tcttgatgtc 250

 acagtttttt gtacttccag ctgtctaaag gcatgaatct cctcttggag 300

 cattctccca gacccttctt tagaagagtc tatactaagt tcttggtgcc 350

 ctcttcggca gccaagggtg aaggccccat agaggagagg atccaaagga 400

 gcattgagga ggcccaagag gaaaaggatg tggctcaggc tgggagggac 450

 ttcagttagc atggtggggg agaaccagta ccacataccc agtaggtaat 500

 aaggtgtcca gcagaggatg aaggtcagca agataagcag ggccagtctc 550

 agggcccgga gacgaacacg gggacaattg tcaaaggagc gggggagggc 600

 aaattcacca gcaggggcta ggaatttaga aaatatactg taattcagac 650

 actcagcttc tgatctgagt atagggtgaa ttgatggagg ggcatagcta 700

 gtgagacaga gctcgcctcc tacaaggagg agaatgttgc aaaccgtttt 750

 ccccttccca acctgggact atatgatttc ttacccccag ggattatgat 800

 agaaatatga agccaccaag tctagacttg atggtgttca agaataaata 850

 atactgattg cctccctagt ccttgtccag ctaactcagc tgtttataat 900

 tgaagggatt caacaaaatt atctctagca tcaggtgcta gacatggtta 950

 gaatctcacc atggtttagt gactggtaga tagctattag gtaggtagat 1000

 aaataaatga tgctagaggc aacaggtcta gggttaagga ttaaggcctg 1050

 ggaattggag tctcaccatg gctccccttc cttgtctggg gcctggacac 1100

 actgaggaca atgcggctat agcagatggc catggcagtc agtggcagca 1150

 gaaagaggca gcagaaggtg aagaggttat aggtggtctc ttgccattga 1200

 gccttgaagc tgcctttggt gacacactga gtgaaaggga ctgggccagc 1250

 tcagtggacc gtgtggaaca ggaacagctg gagtggagtt gaggactatt 1300

 agaactggtt cccctcacca cccaacctac ccacctatgt catactgtct 1350

 cctcccaatt catccttaat tccaagtgaa gcagcacagt gctgagaaac 1400

 agttcatcca tggtgccatg ttaaagaagt tggaaatata tcttgaaaat 1450

 cctatcttcc ttttaggctt gaatatgatg ctgaacagta agtttgttaa 1500

 atcttggaac ttaaaacaat cctgctttct caagtactat tctaacattg 1550

 cgctttataa gggatgatat ttctaccacc tcactcatat ttttagctga 1600

 aatgattttc ctggtatgtc tgttattttg tggaaaaaga aatattgtgt 1650

 aaaatgggtg ctgccaaaat tccaggccat tttgcaggga ctctgaagtg 1700

 acctttagta gtaatagtct tatgtgcagt aactataatg gtaaagaatg 1750

 ttaaataata aaatttaaca ttttccaaat gctattgggc tgcccctccc 1800

 cctttttgtt aaattgctgg gttttccaac tgaatcagta aaaactattt 1850

 ctgtttagag ctacaaggtt aaagtgcctg ctttccagta atggagattg 1900

 agtcactatt aatttgataa aaggtaagct cagtaggcat cagattccta 1950

 gatacaaggc atttgggaaa gtgattttag cagacatgag ggacatttag 2000

 gaaagatgaa tagtttcagc ctaagagaat tttgtgaact gtttggagtt 2050

 acgatcaggc tactctgagc tagttgggaa atggtctttc ctcttcccat 2100

 ctcttgcatt catatatttc taagtttttt ttatttgttt ttgtttttgt 2150

 gctctgccta agaagtgctt gagaattgtg aggagtataa aaatagtcaa 2200

 agcaggcttg agccaccagg cctttctttg ttcttaggag tatagtcaga 2250

 ctaacttcta gtagttatat ttctaataat tgaggatgta agtaaggatc 2300

 aaatcttaaa tcagtataat gcattgtcat tccagagata aatcctagac 2350

 ccttcttggc ctccttctga cataattcta atcctacagt ctcagagatg 2400

 ctgttgtatc ctgcccccca accccatgat agtgatagtg gtttttgcct 2450

 tgaaggaatt gctttgtatt tagcttttcc ccctctagat ttctagttcc 2500

 ttttcagtat tggattggat ttgagatttg attaacctag tactcaggtt 2550

 cagatgctcg cctctttgca attttaacac tcattcgaca ataaagtcag 2600

 taaaaaacac aaaaaaaatc tatgtcgggt gcggagaaag aggtaatgaa 2650

 atggcaggaa actcgatatg caagcttatc gataccgt 2688

<210> 2839
<211> 47
<212> PRT
<213> Homo sapien

<400> 2839
 Ser Cys Cys Val Thr Trp Ala Ser Tyr Val Ser Phe Tyr Ile Arg
   1               5                  10                  15

 His Ser Leu Lys Phe Gln Val Gly Phe Lys Val Glu Thr Leu Val
                  20                  25                  30

 Ser Ile Ser Phe Leu Gly Gly Thr Arg Arg Ala Gly Val Glu Val
                  35                  40                  45

 Arg Cys


<210> 2840
<211> 1700
<212> DNA
<213> Homo sapien

<400> 2840
 acaaagcaaa gggaagaaat aggaaaaaag aaagacttct ctattttctc 50

 atctccctaa cattccttct atctctaaaa ttccagactt ttctacattt 100

 tcctcttcca tggtacccgc cccccaacct ccaccccaac actgacctcc 150

 ttctatattg gcccctcctc ctccttacag ggagcagata gcagggactt 200

 acagatgaac caggccctgc gatttttgga aaatgagcac caggaactgc 250

 aggccaagat tgaatgcctg caaggggaca gagacctgtg cagcttggat 300

 acccaggacc tacaagatca actaaaaagg tcagaggcag agaaactcac 350

 cctggtgacc agagtacagc agttgcaggg tttgcttcaa aatcaatcct 400

 tacagcttca agaacaggag aaactcttaa caaagaaagg tcagcaaatt 450

 tattaccaca aattctaaga tattgctctt ctcttacctg cctagaggca 500

 gcgggatgga ctacatgacc tcctggagtc ccagccagtt ctgggagtct 550

 gttaagtccg ggatgtgtgg gagcttttta aggactgatc attggctctg 600

 aggacacttc aactagttag ccttctatct tgaggtatat aaactgtgaa 650

 aaagggtttc tattctctct gaaagcacat gtctgtgttg aacatttcaa 700

 taaatttatt ttgaactcag gatttcatgt caatttttac acacttgatt 750

 ttccaaatca catccaactc cccagcccca aaccacatag cagtccagag 800

 tcaactcact gttagcccta gagagtctac tgtccatgtt tcctgagaat 850

 tcactgtgta tacagagggg caatagctcc tcacctgtcc actacacacg 900

 accttttgtt ttctcttcac aatcattggg cataatataa tagataaggc 950

 agaaattttt atgctcacag agtatggata agaacatgaa agtctatggt 1000

 gacacaaact aacaacacag ctataacaac aatccaaaac ttctgactcc 1050

 tagtccatgc tcttttcacc aagactaaga ctgcagggtg gctaaaaaac 1100

 catctttaac catatgaaga taaattttag gatatgactg ccatcttcac 1150

 aactttcaaa tgaggacatc agggaaaagg gattgtatta aagcatttac 1200

 caaacttatt tgacaaacta ggaagaatgt gacatacaac caatgaaatt 1250

 caattaagaa gtattcacta aaactatcta gcactagata ggactgggga 1300

 tacaaagaaa agatcccaat cttgccctca aggagctcag attccagctg 1350

 tctgtccaag cttagcaggg gcctactgga agttaacctt tatgtcagag 1400

 aatgccatca gtctagccaa gagcacgccc tcccaagttc cctcccctct 1450

 ccccactcct agtggtttca ccctcagggc ccttcctcag aggtgtgggc 1500

 ctcactgtca ccaagaatct ggctgctttt ttagatcagg ctttgcccgt 1550

 gtggagtcca aagtccttcc ctaacgaagt gtagcctgag ggtacaggga 1600

 aggagaaaga ctgggatctc agagaccagc tgcaaaagaa gactttgcag 1650

 ctccaggcca aggaaaagga gtgcagagaa ctgcattcag aattagacaa 1700

<210> 2841
<211> 87
<212> PRT
<213> Homo sapien

<400> 2841
 Met Asn Gln Ala Leu Arg Phe Leu Glu Asn Glu His Gln Glu Leu
   1               5                  10                  15

 Gln Ala Lys Ile Glu Cys Leu Gln Gly Asp Arg Asp Leu Cys Ser
                  20                  25                  30

 Leu Asp Thr Gln Asp Leu Gln Asp Gln Leu Lys Arg Ser Glu Ala
                  35                  40                  45

 Glu Lys Leu Thr Leu Val Thr Arg Val Gln Gln Leu Gln Gly Leu
                  50                  55                  60

 Leu Gln Asn Gln Ser Leu Gln Leu Gln Glu Gln Glu Lys Leu Leu
                  65                  70                  75

 Thr Lys Lys Gly Gln Gln Ile Tyr Tyr His Lys Phe
                  80                  85

<210> 2842
<211> 570
<212> DNA
<213> Homo sapien

<400> 2842
 ttttccggtt gcggcgccgc gcggtgaggt tgtctagtcc acgctcggag 50

 ccatgccgtc caagggcccg ctgcagtctg tgcaggtctt cggacgcaag 100

 aagacagcga cagctgtggc gcactgcaaa cgcggcaatg gtctcatcaa 150

 ggtgaacggg cggcccctgg agatgattga gccgcgcacg ctacagtaca 200

 agctgctgga gccagttctg cttctcggca aggagcgatt tgctggtgta 250

 gacatccgtg tccgtgtaaa gggtggtggt cacgtggccc agatttatgc 300

 tatccgtcag tccatctcca aagccctggt ggcctattac cagaaatatg 350

 tggatgaggc ttccaagaag gagatcaaag acatcctcat ccagtatgac 400

 cggaccctgc tggtagctga ccctcgtcgc tgcgagtcca aaaagtttgg 450

 aggccctggt gcccgcgctc gctaccagaa atcctaccga taagcccatc 500

 gtgactcaaa actcacttgt ataataaaca gtttttgagg gattttaaag 550

 tttcaaaaaa aaaaaaaaaa 570

<210> 2843
<211> 146
<212> PRT
<213> Homo sapien

<400> 2843
 Met Pro Ser Lys Gly Pro Leu Gln Ser Val Gln Val Phe Gly Arg
   1               5                  10                  15

 Lys Lys Thr Ala Thr Ala Val Ala His Cys Lys Arg Gly Asn Gly
                  20                  25                  30

 Leu Ile Lys Val Asn Gly Arg Pro Leu Glu Met Ile Glu Pro Arg
                  35                  40                  45

 Thr Leu Gln Tyr Lys Leu Leu Glu Pro Val Leu Leu Leu Gly Lys
                  50                  55                  60

 Glu Arg Phe Ala Gly Val Asp Ile Arg Val Arg Val Lys Gly Gly
                  65                  70                  75

 Gly His Val Ala Gln Ile Tyr Ala Ile Arg Gln Ser Ile Ser Lys
                  80                  85                  90

 Ala Leu Val Ala Tyr Tyr Gln Lys Tyr Val Asp Glu Ala Ser Lys
                  95                 100                 105

 Lys Glu Ile Lys Asp Ile Leu Ile Gln Tyr Asp Arg Thr Leu Leu
                 110                 115                 120

 Val Ala Asp Pro Arg Arg Cys Glu Ser Lys Lys Phe Gly Gly Pro
                 125                 130                 135

 Gly Ala Arg Ala Arg Tyr Gln Lys Ser Tyr Arg
                 140                 145

<210> 2844
<211> 3587
<212> DNA
<213> Homo sapien

<400> 2844
 gaattcagca caatgaagga gccatggaat gccaatttaa cgtcagtctt 50

 gtacttgaag ggaaaaaaaa cacttgtaat ggtggcaaca gtgaagctgt 100

 tcctttaaca tccccaaata tagccaagtt tagcactcca ccagccatcc 150

 tcagaaagaa gagaaaaatg cgagtgggtc attccccagg cagcgaactt 200

 agggatggct cattgaacga tggtggtaat atggcgctaa aacatacacc 250

 actgaaaaca ctaccatttt ctccttcaca gtttttcaac acatgtcctg 300

 gtaatgaaca acttaatata gaaaatcctt catttacatc aacccctatt 350

 tgtgggcaga aagctctcat tacaactcct cttcataagg aaacaactcc 400

 caaagatcaa aaggaaaatg tagggtttag aacacctact attagaagat 450

 ctatactggg taccacacca agaactccta ctccttttaa gaatgcgctt 500

 gctgctcagg agaaaaaata tggacctctt aaaattgtgt cccagccact 550

 tgctttcttg gaagaagata ttcgggaagt tttaaaagaa gaaactggaa 600

 cagacctatt cctcaaagag gaagatgaac ctgcttacaa aagctgcaaa 650

 caagagaata ccgcttctgg gaagaaagtc agaaaatcac tagtcttaga 700

 taattgggaa aaagaagaat caggcactca actgttgact gaagacattt 750

 cagacatgca gtcagaaaat agatttacta catccttatt aatgatacca 800

 ttattggaaa tacatgacaa taggtgcaac ttgattcctg aaaaacaaga 850

 tataaattca accaacaaaa catatacact tactaaaaag aaaccaaacc 900

 ctaacacttc caaagttgtc aaattggaaa agaatcttca gtcaaattgt 950

 gaatgggaaa cagtggttta tgggaagaca gaagaccaac ttattatgac 1000

 tgaacaagca agaagatatc tgagtactta cacagctacc agtagtactt 1050

 caagagctct catactgtaa ttgttattaa aattgatgaa atgccccact 1100

 cccttactgc agtctctact aaattaggtt gcagtgaaat ttttctcaat 1150

 tagttgtttt taaagttgta agataccctt ttaatacagc atcttttttc 1200

 tattctatat agtaggcaga aagctagtaa gtcacttaag gggtagatag 1250

 tttcatagtt tattttttaa gagatgagat ttttaaaaat tgtttttaaa 1300

 gaacaagatg ggaaaataat agaatgttca tggatttcta aaagtaaatt 1350

 ctcatatatt ttcttcacaa gatatatgtt gctactctct tgatgctgca 1400

 gttttgttat agataggtgt atgagtatat atgatttctg aaattagtct 1450

 atgtatggaa agcacacatg attttatgaa ggtacttttg cccatgtgct 1500

 gatttactta ggctaccatt tacaaagaaa cacattgaaa aggaatttaa 1550

 aggaaggata gaaagttgca ctactaattt tttgtttttt ttttcagaag 1600

 cagtaaaatt aactacagtg ttaaatgtat ttatttgagc atagtactga 1650

 aaacaaaaag cattcaaaaa agagtttttt ctttattagt aaatagtatt 1700

 ttcttaatct cagaggagct gagagttttg ttgaatgtat tgtacagtat 1750

 gtaggagcag gagaactttg taaattggaa agaagtctgt ttttataatt 1800

 tatttttatt tttaaagctt aaatgtagat atttatagta tacagggagc 1850

 ctagaagcca atgttgtttc ctgttattac agctaacaca gtaaagaata 1900

 attttgactt taagtatgaa acagtagtaa gttatagctg caaagaatac 1950

 aatatctata ctgtatgtca catctaccta aatgttgcac tatgcccttt 2000

 aaatcatgct ggttataaag tagttctaaa aatgtactaa ataataattt 2050

 aatattttct ttttaaatta tatcgggggt ggtcatatac attaatctgg 2100

 tgatttgtat atgtgtttga aattttttgc ttttgtttaa aaaaaaataa 2150

 tatggtacct tggtccctaa aaacagtctg cacttagaag ttatatttac 2200

 tcagtgtttc agaagtggag aacttatctt ttatttataa aaatattttg 2250

 tcctttttta aatgttttgt gtttctctac aggttacaac agttgcttca 2300

 gttgcctgtt ttaggtgttt gcacttattt tatttcttct tgaaagaatt 2350

 tttatttgct tttgtggtag agattatatg taattttttt tcagtcatat 2400

 aatggtgtgc tgtcaactta aacactgaca ggtaaataga attgtacact 2450

 gtagtttgaa ttatttataa ttgacacact ctctccctct ccactcctga 2500

 agtatgctgc tatagaaaat agcagaatcg gcttgctgct acgagagaag 2550

 gaaagagcga ccaccacttg cactgtgtga aaagataaaa aacaaatgat 2600

 ggcaagttct caagttaact aaatggaatc aaccattacc aggcaaattc 2650

 ttgcaaatac caaaatacta ctatgcctta taaaacaaaa tgaaagcagg 2700

 ttaagatttt ctgctctgtt tgtatgttaa tagaaatgga aatactaagt 2750

 attttaatgc ttagctattg aacagtagac ctaaaagggt tttaagctat 2800

 ttaaatctac ttgctagttt ttgcatattt tatatatata tatatttata 2850

 tatatatata gtgagaagtg aagaaaatgt atggtactaa gattatgcct 2900

 tattgataaa tagataaacc aatttgaatc ctcttagcat gtttaagtat 2950

 gttgattgct ttctaattaa tgaacttctc acagaaattt cacttagtga 3000

 aaccaatgat tgtagcaaac tcatactgga tcatttcagt taccttgaac 3050

 taatagcaca taatggtttt ttgttgttgt tgtttttaat gtagccctta 3100

 cctggatata catagtctgc aatcaccaaa gtataatatc ttgtaaggct 3150

 atatttttta aagcatattt tttcttgagc attaaattat cctaaatggt 3200

 aatatattgt ggataagtct gggcttattg gacataatac atatttgggt 3250

 tggtactggt tgaatccttc agttaactgc tttgttgctt tttgcaagat 3300

 tttttatctt aaacatgtca ggcatcttaa gtcaccttta tactgttttg 3350

 ttcctctgag tttctttcag tatgttatac aaatgccaga cataacatgt 3400

 agcagccata cttgcatgga aactgactac acatacataa tactgcattt 3450

 tattgtaagg ttttcacatt aatacagcaa ttaccctgac taaattgagt 3500

 tttgtgatat atggaaaact tcattgtaag agaatcttgc atacaatgtt 3550

 gactattaac atccaaaata aagcatctgt gtacaag 3587

<210> 2845
<211> 783
<212> DNA
<213> Homo sapien

<400> 2845
 cccaggagtc tgggtgcaca gcctccttct ctctgagatt caagagtctg 50

 atcagcagcc tcttcctcct ccaggaccca gaagccctga gcttatcccc 100

 atggagctct gccggtccct ggccctgctg gggggctccc tgggcctgat 150

 gttctgcctg attgctttga gcaccgattt ctggtttgag gctgtgggtc 200

 ccacccactc agctcactcg ggcctctggc caacagggca tggggacatc 250

 atatcaggct acatccacgt gacgcagacc ttcagcatta tggctgttct 300

 gtgggccctg gtgtccgtga gcttcctggt cctgtcctgc ttcccctcac 350

 tgttcccccc aggccacggc ccgcttgtct caaccaccgc agcctttgct 400

 gcagccatct ccatggtggt ggccatggcg gtgtacacca gcgagcggtg 450

 ggaccagcct ccacaccccc agatccagac cttcttctcc tggtccttct 500

 acctgggctg ggtctcagct atcctcttgc tctgtacagg tgccctgagc 550

 ctgggtgctc actgtggcgg tccccgtcct ggctatgaaa ccttgtgagc 600

 agaaggcaag agcggcaaga tgagttttga gcgttgtatt ccaaaggcct 650

 catctggagc ctcgggaaag tctggtccta catttgcccg cccttccagc 700

 ccttccccag cccctcctct tgtttcttca ttcattcaac aaaatttggc 750

 tggaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 783

<210> 2846
<211> 165
<212> PRT
<213> Homo sapien

<400> 2846
 Met Glu Leu Cys Arg Ser Leu Ala Leu Leu Gly Gly Ser Leu Gly
   1               5                  10                  15

 Leu Met Phe Cys Leu Ile Ala Leu Ser Thr Asp Phe Trp Phe Glu
                  20                  25                  30

 Ala Val Gly Pro Thr His Ser Ala His Ser Gly Leu Trp Pro Thr
                  35                  40                  45

 Gly His Gly Asp Ile Ile Ser Gly Tyr Ile His Val Thr Gln Thr
                  50                  55                  60

 Phe Ser Ile Met Ala Val Leu Trp Ala Leu Val Ser Val Ser Phe
                  65                  70                  75

 Leu Val Leu Ser Cys Phe Pro Ser Leu Phe Pro Pro Gly His Gly
                  80                  85                  90

 Pro Leu Val Ser Thr Thr Ala Ala Phe Ala Ala Ala Ile Ser Met
                  95                 100                 105

 Val Val Ala Met Ala Val Tyr Thr Ser Glu Arg Trp Asp Gln Pro
                 110                 115                 120

 Pro His Pro Gln Ile Gln Thr Phe Phe Ser Trp Ser Phe Tyr Leu
                 125                 130                 135

 Gly Trp Val Ser Ala Ile Leu Leu Leu Cys Thr Gly Ala Leu Ser
                 140                 145                 150

 Leu Gly Ala His Cys Gly Gly Pro Arg Pro Gly Tyr Glu Thr Leu
                 155                 160                 165

<210> 2847
<211> 1315
<212> DNA
<213> Homo sapien

<400> 2847
 agccctattt atctgattat ttaagtaaaa ctttaataaa ccatgaccta 50

 cattttctat gcaattttaa gatactcaga gttaatattt taatattgag 100

 gttcttgatt tttttaatga tcagctttca aattatattt cagtatatac 150

 tctgagtcta cgtgtatgct acaaaaggtg aaatgaagtt agcttatttt 200

 tcagtgagtt taggctatat taagagttag gtaagttagg taagggtgaa 250

 actgctttgg ggcccagact gcgctggaat gtactgttta aattcaaagg 300

 taattgatgg ccagtgttca gttgctctat ttgtaacgtt tgcatgttgg 350

 tctggctgaa gtatcaggaa aacacaaaat tcatgaaaat agcacctttt 400

 ataattttat acttttataa agcacttgtt aaagaagtat agcaaatttc 450

 tatgtatttt aacatacaag tcgctgcatt ttaatgttca tttttggtat 500

 agctatggta acttataata gtcattttta tattcataac ttgttttctg 550

 aaagatatag tcattattaa aataaacatt catgtaaatg gagtaaatca 600

 taggggaatc aatcgtaata aataccttat aaattataaa cttgtttaga 650

 tactagattt ctataaccat aaattttata ctgtaaagtc tgtttaaaat 700

 agggtttaat gaagttattt taatttttag agactcccct ctaaataatt 750

 tactcctaca ttgtaaatac attgatgcca acaaaattcc aactgctact 800

 aacaaaggtt tggttggtga taagctaata acagctactt tgtgtaggag 850

 gtaaatatgt gtactggagg gggtaaaaat ccatttaggt tatggcaaag 900

 atgggaatca aactgtaaaa ctcatagccc cataaaatta atattctttg 950

 ttaagtgcca gagggtttaa gagaacttct tgcttagagt ttattgataa 1000

 taataatgct tcagaatatc ccatttaaat gtacagtgta aatatgtaaa 1050

 atattttact tcccaggcaa gtttgtggct gtattgccac ttagtggctc 1100

 tttgtgactg gcagttctgt atatctgaaa caaataagct gtaagcactt 1150

 ttgttaaaac tttgtcaaat aatcctttta tgtacttgtt ctcagacctg 1200

 ttctctggtt atgaaatgtg ttaaagacaa ggtgcaaatt taaaacaatg 1250

 cctgtattga aataaatgac ttaaacagaa aaaaaaaaac ctagtagtcg 1300

 gggggaacca ctagt 1315

<210> 2848
<211> 50
<212> PRT
<213> Homo sapien

<400> 2848
 Pro Tyr Leu Ser Asp Tyr Leu Ser Lys Thr Leu Ile Asn His Asp
   1               5                  10                  15

 Leu His Phe Leu Cys Asn Phe Lys Ile Leu Arg Val Asn Ile Leu
                  20                  25                  30

 Ile Leu Arg Phe Leu Ile Phe Leu Met Ile Ser Phe Gln Ile Ile
                  35                  40                  45

 Phe Gln Tyr Ile Leu
                  50

<210> 2849
<211> 2229
<212> DNA
<213> Homo sapien

<400> 2849
 tggaagcgcc cgctcgtctt gatagacgtg ccaccttccg ccaatgggga 50

 cgaagggaag ctccagcgtg tggccccggc gagtgcggat aaaagccgcc 100

 ccgccgggct cgggcttcat tctgagccga gcccggtgcc aagcgcagct 150

 agctcagcag gcggcagcgg cggcctgagc ttcagggcag ccagctccct 200

 cccggtctcg ccttccctcg cggtcagcat gaaagccttc agtcccgtga 250

 ggtccgttag gaaaaacagc ctgtcggacc acagcctggg catctcccgg 300

 agcaaaaccc ctgtggacga cccgatgagc ctgctataca acatgaacga 350

 ctgctactcc aagctcaagg agctggtgcc cagcatcccc cagaacaaga 400

 aggtgagcaa gatggaaatc ctgcagcacg tcatcgacta catcttggac 450

 ctgcagatcg ccctggactc gcatcccact attgtcagcc tgcatcacca 500

 gagacccggg cagaaccagg cgtccaggac gccgctgacc accctcaaca 550

 cggatatcag catcctgtcc ttgcaggtaa gacctgctcc ggggtccccg 600

 ccccgccgcc gcacactccc gcggtcgtct gggctgtcac taggagatcc 650

 gtagcccaga cggtgacttt cgtatgagct atttaacttt attttcttca 700

 gaatctgctg tagattgagc tgtgcgtgaa attgctagta agttctgaca 750

 tgttaatgcg tctgtcttta aatctgaatt gttaccataa acgtgtttaa 800

 tggaacttgc tggtctgtgg actacaaaaa aaaagaaaaa aaaacaaaaa 850

 ccctttctac ttaacattgt cttaacctcg tactctttat cctctttctt 900

 tccaggcttc tgaattccct tctgagttaa tgtcaaatga cagcaaagca 950

 ctgtgtggct gaataagcgg tgagtgtttg cttgtgccac ccgtgggtaa 1000

 actgcccctc ggtgtgtgtg cgcgcgcgcg catgtgtttt tgcttgtgta 1050

 tctataaaat gtctgatttg gtaaatgcat gcttacttcg cggtgttacc 1100

 cgtactacat tgtctcacta gacatgaagg agcttgtagc tttgggtgct 1150

 cgagatcaca gaacattttc ctttaaaagg aaatgatgcc aataacttac 1200

 tacgaaggcg gccgaggaac gtgtgtattg gctttgtagc aaatgtaatg 1250

 ccctggatct tcctacgagt cctctggtac tatgaggtac taacctccac 1300

 tgtaattaat cttaccgcca caaattccat agtgatcctc cttccctaaa 1350

 actatagtcc tctgggattc tctgggctag ttgaggattg ctaccctgtg 1400

 ccttcaaccc tgtgatgtgg gatcccagac ttccctatct gttaactaaa 1450

 gggctgtttt caatcaaata attgttacga gaagcagact ggcgcctgta 1500

 gcactgctgt tggagatcca aataggagat tgggttggga agtttttccc 1550

 ttgagtctct gctattttaa tgtttaattt gcgctgtcga ggcgagtgtg 1600

 tgtgttgcat ctggacgcca gggtttgccc aatctttgag tgtttggtta 1650

 aatgttcaaa ctgtggcttc ctcccggcgc cagtcgcccg cctctgccct 1700

 taggttacat tctcttaaac atgcctttct cccccactct ttcgcaggtg 1750

 ttcatgattt cttttattct ttgcacaaca acaacaacaa caaattcacg 1800

 gaatctttta agtgctgaac ttatttttca accatttcac aaggaggaca 1850

 agttgaatgg acctttttaa aaagaaaaaa aaaatggaag gaaaactaag 1900

 aatgatcatc ttcccagggt gttctcttac ttggactgtg atattcgtta 1950

 tttatgaaaa agacttttaa atgccctttc tgcagttgga aggttttctt 2000

 tatatactat tcccaccatg gggagcgaaa acgttaaaat cacaaggaat 2050

 tgcccaatct aagcagactt ggcctttttt caaaggtgga gcgtgaatac 2100

 cagaaggatc cagtattcag tcacttaaat gaagtctttc ggtcagaaat 2150

 tacctttttg acacaagcct actgaatgct gtgtatatat catatataaa 2200

 tatatctatt cgagtgaaac cttgtgaac 2229

<210> 2850
<211> 217
<212> PRT
<213> Homo sapien

<400> 2850
 Trp Lys Arg Pro Leu Val Leu Ile Asp Val Pro Pro Ser Ala Asn
   1               5                  10                  15

 Gly Asp Glu Gly Lys Leu Gln Arg Val Ala Pro Ala Ser Ala Asp
                  20                  25                  30

 Lys Ser Arg Pro Ala Gly Leu Gly Leu His Ser Glu Pro Ser Pro
                  35                  40                  45

 Val Pro Ser Ala Ala Ser Ser Ala Gly Gly Ser Gly Gly Leu Ser
                  50                  55                  60

 Phe Arg Ala Ala Ser Ser Leu Pro Val Ser Pro Ser Leu Ala Val
                  65                  70                  75

 Ser Met Lys Ala Phe Ser Pro Val Arg Ser Val Arg Lys Asn Ser
                  80                  85                  90

 Leu Ser Asp His Ser Leu Gly Ile Ser Arg Ser Lys Thr Pro Val
                  95                 100                 105

 Asp Asp Pro Met Ser Leu Leu Tyr Asn Met Asn Asp Cys Tyr Ser
                 110                 115                 120

 Lys Leu Lys Glu Leu Val Pro Ser Ile Pro Gln Asn Lys Lys Val
                 125                 130                 135

 Ser Lys Met Glu Ile Leu Gln His Val Ile Asp Tyr Ile Leu Asp
                 140                 145                 150

 Leu Gln Ile Ala Leu Asp Ser His Pro Thr Ile Val Ser Leu His
                 155                 160                 165

 His Gln Arg Pro Gly Gln Asn Gln Ala Ser Arg Thr Pro Leu Thr
                 170                 175                 180

 Thr Leu Asn Thr Asp Ile Ser Ile Leu Ser Leu Gln Val Arg Pro
                 185                 190                 195

 Ala Pro Gly Ser Pro Pro Arg Arg Arg Thr Leu Pro Arg Ser Ser
                 200                 205                 210

 Gly Leu Ser Leu Gly Asp Pro
                 215

<210> 2851
<211> 11740
<212> DNA
<213> Homo sapien

<400> 2851
 cccggagccg gtgcgaggag ggcacccggt gcgtccccgg agcggggagg 50

 ccaggccggg caaccctggg gccggtcggg gcggcgtcac tgcaccctcc 100

 gccaggctcc gcgggatgca ccgtggtagc cgagggcgga ggcgacactc 150

 tcaggtaaat tggcaggatg aggagcagca aatcaaaaga ggtgccttta 200

 ccaaatccaa ggaactctca aagcaaggat actgttcaag cagatataac 250

 cacatcgtgg gatgcacttt ctcaaaccaa ggctgctctg agacacattg 300

 aaaataaatt agaagtagcc cctacaagta cagctgtgtg tgattctgtc 350

 atggatacca agaagtcttc tacaagtgct actcgaaaaa taagtagaaa 400

 agatggtaga tacctggatg attcttgggt taatgctcca atctccaaat 450

 ccactaaatc acgaaaagag aaatctcgta gtcctctcag ggccaccacc 500

 ctggagggta atgtgaagaa aaataatcgt gtggaatttc gtgaaccttt 550

 ggtttcttat agggaaatcc atggtgcacc ttccaatttc agttccagcc 600

 atctggaatc aaagcacgta tactgtgtag atgttaatga agaaaagact 650

 gagagcggta actggatgat aggcagtcga gaagaacgga atatacggag 700

 ctgtgatttt gagagctccc aatcatctgt catcaatgat acagttgtta 750

 ggtttttaaa tgatcgacca gcaattgatg cattgcaaaa ttctgaatgt 800

 ttgattagga tgggagcttc tatgagaact gaggaagaaa tgcctaacag 850

 aacaaaagga agtgagaata atttgaagct ttctgtgaat aacatggccc 900

 atgatactga tccaaaagcg ttacgactaa ctgactcttc tccatcctct 950

 actagtactt ctaattccca aagattagat attctaaagc ggcgacaaca 1000

 tgatgtcaaa ctggaaaaac ttaaggaacg gattagaaaa cagtgggaac 1050

 actcagaaga aacaaatggc cggggccaga agctgggtca tattgaccat 1100

 ccagtaatgg ttgttaatgt tgataactca gtaacagcaa aagtcagaaa 1150

 agtggcaaca gcaccacctg ctccagcata taaaggtttc aacccttcag 1200

 agaccaagat tcgaacacct gatgggaaag tgtggcagga ggctgagttt 1250

 caaaacatga gtagagaact gtatcgagat ttagcacttc actttgcaga 1300

 tgatatttct ataaaggaga aacctgctga aaaaagtaaa gagaagaaag 1350

 tagtcaagcc agtacgaaaa gtccaaaaag tagcacagtt atcaagtaca 1400

 gaatgcagaa caggtagtag tcatcttata agtacatctt cttggcgaga 1450

 tggacaaaaa ttagtaaaga agattctggg acctgctccc agaatggagc 1500

 caaaagagca aagaacagca tcaagtgaca gaggtggaag aagaagaact 1550

 gctaaatctg ggggtcacat tggaagagca gaatctgatc ccaggttgga 1600

 cgttttacat agacatcttc aaagaaactc agaacgttcg agaagtaaat 1650

 ctcggtctga aaataatata aagaaactag cttcatctct tccagataat 1700

 aagcaggagg aaaatactgc cttaaataag gactttttac ctattgaaat 1750

 tcgtggcatt cttgatgacc tacagctgga ttctacagct cacactgcaa 1800

 agcaagatac tgtagagtta cagaaccaga agtcatcagc accagtacat 1850

 gctcctagga gtcacagccc agtaaaaaga aaacctgaca aaataacagc 1900

 taatgaagat ccccctgtta tttccaaaag gcgccactat gacacagatg 1950

 aggtacgaca gtacattgtt aggcagcagg aggaaaggaa gagaaagcaa 2000

 aatgaagaga agaaggctca aaaggaggct acagaacaga aaaacaaacg 2050

 attacaagag ctctaccgga agcagaagga agcctttact aaagtaaaaa 2100

 atgtccctcc ttctgagcca tcagcaacta ggcgactaca ggaaacttac 2150

 tccaaattgc tactagaaaa gaccttgctt gaagagccat ctcatcaaca 2200

 tgttacgcag gaaacacagg ccaaaccagg gtatcagcca tctggagaat 2250

 ctgacaaaga aaacaaagta caggaacgtc ccccaagtgc atcttccagt 2300

 agtgacatgt ctctctcaga acctccacag cctcttgcaa gaaaagactt 2350

 gatggaatct acatggatgc agcctgaaag attgagccca caagttcacc 2400

 attctcaacc acagcctttt gctggaacag ctggaagttt actctcccat 2450

 ctcttgagtt tagagcatgt aggaattttg cataaggatt ttgaatctat 2500

 tttaccaacc aggaagaatc ataatatggc ttcaaggcca ttaactttta 2550

 cacctcaacc atatgtgacc tcaccagctg cttatacaga tgccttgtta 2600

 aaacctagtg ccagccaata taagagtaaa ctggatcgta ttgaagcctt 2650

 gaaagcaaca gctgcttctt tgtccagcag aattgaaagt gaagccaaga 2700

 aattagctgg ggccagcatt aactatgggt cagcatggaa cactgagtat 2750

 gatgtgcagc aggcacctca agaagatgga ccttggacca aggctgtaac 2800

 tccacctgtg aaagatgata atgaagatgt tttctctgcc agaattcaga 2850

 agatgctggg aagctgtgta tctcatgcaa cttttgatga tgatcttcct 2900

 ggtgtaggca atcttagtga atttaaaaag cttcctgaga tgataagacc 2950

 acagagtgcc atatcaagct ttagagtgag atcccctggt cccaaaccac 3000

 aagggctact ggcacagtta tgtaaaaggc agactgactc ttctagctct 3050

 gatatgcaag cctgttctca agacaaagcc aaaatatctc ttggttccag 3100

 catagattca gtcagtgaag ggcctcttct tagtgagggg agtctctctg 3150

 aagaagaggg agaccaggat ggacagcccc ttttgaaagt agcagaaatt 3200

 ttaaaagaaa aggaattttg tcctggagaa agaaatagtt atgaacccat 3250

 caaagagttt cagaaagaag ctgaaaaatt cttgccactt tttgggcaca 3300

 taggtggtac acaaagcaaa ggaccatggg aagaattggc aaagggaagt 3350

 ccacatagcg tcattaatat ttttacaaaa tcctatcagt tatatggaaa 3400

 agggtttgaa gacaagttgg acagaggaac atcaacatca cggcctttga 3450

 atgccaccgc aactcctcta agtggtgttt catatgaaga tgattttgtc 3500

 tcctctccag ggactgggac ttcgacagaa aaaaaatcaa ctcttgaacc 3550

 tcatagcact ttaagccctc aggaggacca ttctaacaga aagtctgcct 3600

 atgatccttc ctctgtggat gttacctccc agcattcatc aggagcccag 3650

 tctgctgcat cgtctcgttc atctacttct tctaaaggaa agaaaggaaa 3700

 aaaggaaaag acagaatggt tggattcatt cactggaaat gttcagaact 3750

 cacttcttga tgaggaaaaa gcagaacgtg gctcccatca aggaaagaaa 3800

 tctgggacca gcagcaaact ttctgttaaa gattttgagc agactcttga 3850

 tacagatagc actttggagg atctttctgg acattctgtg agtgtctcat 3900

 cagataaggg aagatctcag aaaactccaa cttctcccct gtcaccaagt 3950

 tcccagaaat cattgcagtt tgacgttgca ggaacttctt cagaaagatc 4000

 taagtcgtca gtaatgcctc caactataac aggatttaag cctaatgcac 4050

 ctctcactga tctgaacccg gcagccagca gaacaacgac agagaacatg 4100

 gctccaatac caggttctaa gcgcttttct cctgctggcc tccatcatcg 4150

 tatggcagca gaactcagtt atctgaacgc cattgaggag tcggtgcgcc 4200

 aactgtcaga tgtagaaaga gttagaggca tttcacttgc tcagcaggag 4250

 agtgtgtctc tagctcagat aataaaggca caacagcaac gccatgaaag 4300

 agacttggcc ctcttgaaac taaaggctga acaagaggct ctggagagtc 4350

 agagacaatt agaagaaacc cgaaacaaag cagctcaggt ccatgcagaa 4400

 tcattacagc aggtggttca atcacaacgg gaagtaactg aagtcctgca 4450

 ggaagcaacg tgtaaaatag cagctcagca gtcagaaact gctcgcctca 4500

 ccacagacgc agcacgtcaa atctgtgaga tggcagagtt gactagaact 4550

 catatctcag atgctgtcgt ggcttcagga gctccccttg caatactgta 4600

 tgaccaccaa cggcagcacc ttccagactt tgtgaaacag ctgaggacca 4650

 gaactgaaac agataggaaa agtccatctg tttcactctc tcagagtaaa 4700

 gaagggaccc ttgactcaaa gcatcagaag tattctgctt catatgatag 4750

 ttattctgag tcttcaggat acaagaatca tgatagaaga agtagcagtg 4800

 gtagcagccg ccaagaaagt ccttcagttc catcttgtaa ggaaaatgag 4850

 aagaaactta atggtgaaaa gatagagagt tccattgatg aacaggttca 4900

 gactgctgca gatgattctc tacgaagtga tagtgttcca tctcttcctg 4950

 atgaaaaaga ctcaacgtct attgcaacag aatattctct gaaatttgat 5000

 gaatccatga cagaagatga aatagaagaa caatcatttc gatcattact 5050

 accttcagag agtcaccgca gatttaacat ggaaaagaga agaggtcatc 5100

 atgatgactc tgatgaagaa gcttctccag aaaaaactac actgtctact 5150

 gccaaggaac tgaacatgcc attctcagga ggacaagata gcttttctaa 5200

 atttactatg gagatggttc gacagtatat gaaagaggaa gaaatgaggg 5250

 cagctcacca gtcttcactc ctgcgtctcc gtgaaaaggc cttgaaggag 5300

 aagactaagg ctgaattggc ctggttagag catcaaaaaa aacatctacg 5350

 agacaaagga gaggatgata aaatgccccc gctccggaag aaacagcgtg 5400

 gtttgctttt aaggttgcag caagaaaagg cagaaataaa acgtcttcaa 5450

 gaagccaata aggcagctcg gaaggaaaga cagctgattc ttaaacagca 5500

 ggaggagata gaaaagatcc gacagaccac cataaaacta caggagaaat 5550

 tgaagtctgc aggggagagt aaattggact ctcatagtga tgatgataca 5600

 aaggataata aggcaaccag tcctggtcca actgacttgg agacccgcag 5650

 tccttctccc atttcaatct ccagcagtga aactagcagc attatgcaga 5700

 aactgaagaa aatgagaagc cgcatggatg aaaagtttct gacaaagcgg 5750

 gagcaaaaat taatgcaacg gcgacaacat gcagaggagc tcctagagtg 5800

 gaagcgacgt ttagatgcag aagaagcaga aattcgtcaa atggaaaaac 5850

 aagctttggc tgcctgggac aaagaattaa taaaacccaa aactcctaag 5900

 aaagaactgg aggaccagag aacagaacag aaagaaatag caagtgaaga 5950

 ggaatctcca gtacctctgt actctcatct aaacagtgaa agctccattc 6000

 cagaagaatt aggcagccct gctgttgaat atgtaccatc cgagtctata 6050

 ggacaggagc agccagggag tccagatcac agtatactta ctgaagaaat 6100

 gatttgttca caggaactag aatcttctac ctctcctagt aaacattcac 6150

 ttcccaaaag ctgcacatct gtgtcaaagc aggagtctag caaaggaagt 6200

 cataggactg gaggacaatg tcacctgcct atcaagtccc atcagcactg 6250

 ttatagttgg tcagatgagt cattatctat gacacagtca gaaactacat 6300

 ctgaccagag tgatattgaa ggtaggatca gagctctgaa ggatgagttg 6350

 cggaaaagaa aatcagttgt gaaccagctg aagaaggaac agaaaaaaag 6400

 gcaaaaggaa agactgaaag cccaagaagc cagtctgatc aagcagttag 6450

 agtcatatga tgaatttatt aagaaaactg aagccgagct tagccaagat 6500

 ttggaaacat caccaacagc caagcctcag attaaaacgc tctcctcagc 6550

 ttctgaaaaa cccaagatca aacccctcac accactacac agatctgaaa 6600

 cggcaaagaa ttggaaatca ctaacagagt cagaacgttc cagaggatcc 6650

 ctggagccta ttgctgaaca tgttgatgct tcactgtctg gttctgagag 6700

 atcagtatca gaaaggtctt tatctgcata tgcaaagaga gtaaatgaat 6750

 gggacagtcg aacagaagat tttcagaccc catctccagt tctcagatca 6800

 tcaaggaaaa tcagagaaga atctggagat tctctagaaa atgtacctgc 6850

 attacatctt ctcaaagaat taaatgccac tagtagaatt cttgatatgt 6900

 cagatggcaa ggttggagaa tctagtaaaa aatcagaaat aaaagaaata 6950

 gagtatacaa aattgaagaa gagtaagatt gaagatgcct tttctaaaga 7000

 aggtaaatct gatgtcttac tgaaattagt cctagaacag ggagattcat 7050

 ctgaaattct ttcaaagaaa gatcttcctt tagattctga aaatgttcag 7100

 aaagacctag ttggattagc tattgaaaat ctccataaaa gtgaggaaat 7150

 gttgaaagag agacagtcag atcaagatat gaatcatagt ccaaacatcc 7200

 aatcaggaaa agacattcac gaacaaaaga acacaaagga aaaagatttg 7250

 tcttggtcag aacatctttt tgctcctaaa gagataccat actctgaaga 7300

 ttttgaagtg tcttctttca agaaagaaat ttcagctgaa ttgtacaaag 7350

 atgattttga ggtgtcatct ttgctgtcac tcaggaaaga ctctcagtct 7400

 tgcagagata agccacagcc aatgaggagc tctacaagtg gagccactag 7450

 ctttggtagt aatgaggaaa tcagtgagtg cctaagtgag aaaagccttt 7500

 ctatccatag caatgttcat tctgacaggc tgttggaact caagtcccct 7550

 actgagctga tgaaaagtaa ggagcgcagt gatgtggagc atgaacagca 7600

 agttactgaa tccccttcct tggcttcagt tcctactgca gacgagttat 7650

 ttgatttcca cattggtgat agggtgttga ttggaaatgt tcagccagga 7700

 attcttcgat tcaaaggtga gactagtttt gctaaaggat tttgggccgg 7750

 agtggagtta gataaacctg aaggaaataa caatggaaca tatgatggta 7800

 ttgcatattt tgagtgcaaa gaaaagcatg gtatttttgc tcctcctcaa 7850

 aaaatatctc acattccaga aaactttgat gactatgtag acattaatga 7900

 agatgaagac tgttactcag atgaacgata tcagtgctat aatcaagagc 7950

 aaaatgatac agagggtcca aaagacagag aaaaggatgt cagtgaatat 8000

 ttttatgaga aatccctacc tagtgtgaat gatatagaag cctcagttaa 8050

 tagaagtaga agccttaaaa tagaaacaga caatgtacag gacatttctg 8100

 gggtacttga agcccatgtt caccagcagt cttcagtgga ttcacagatt 8150

 tcttcaaagg aaaacaaaga cctcatttct gatgccacag aaaaggtttc 8200

 catcgctgca gaagatgaca ctttagacaa taccttttcc gaagaattgg 8250

 agaagcaaca gcagtttaca gaagaggaag acaacctata tgctgaagct 8300

 tcagaaaagc tttgtacacc acttctggat cttttaacaa gagaaaaaaa 8350

 ccaactggaa gcccagctga agtcatcact aaatgaggaa aaaaagtcaa 8400

 aacaacaact ggaaaaaatc agcttactga cagacagttt actaaaagtc 8450

 tttgtaaagg acacagtcaa tcaactacaa caaatcaaaa aaaccaggga 8500

 tgagaaaatc cagcttagca atcaggagct tcttggtgat gaccaaaaga 8550

 aagtaacacc ccaagaccta tcccaaaatg ttgaggaaca gtcgccaagt 8600

 atttcaggtt gcttcttaag ttctgaattg gaagatgaaa aagaagagat 8650

 ttcctctcca gatatgtgtc ccagaccgga gagcccagta tttggtgcca 8700

 gtgggcagga agaacttgct aagagacttg ctgaacttga actcagccgg 8750

 gagttcctga gcgcgttagg agatgatcaa gactggtttg atgaagactt 8800

 tggtttgagc tcttctcaca agatccaaaa aaataaggca gaagaaacca 8850

 ttgtacctct aatggcagaa cctaaaagag taacccaaca accatgtgaa 8900

 acattattgg cagtccccca tactgcagaa gaagtagaga ttcttgtaca 8950

 taatgcagca gaagaacttt ggaaatggaa agaattaggc cacgatcttc 9000

 atagcatcag tattcctaca aaactgcttg gctgtgccag taaaggtcta 9050

 gatatagaaa gcactagtaa aagggtctac aaacaggcgg tttttgattt 9100

 aacaaaagag atttttgagg aaatatttgc tgaggatccc aacttaaatc 9150

 aacctgtctg gatgaagcca tgtagaatca actctagtta tttccgacga 9200

 gtgaaaaatc caaataacct tgatgaaatc aagagcttca tagcaagtga 9250

 agtactcaag ttgttcagtc ttaaaaagga gccaaaccac aaaacagatt 9300

 ggcagaaaat gatgaaattt ggaagaaaga aaagagaccg agtggatcat 9350

 atcctggttc aggagctcca tgaggaggag gcacagtggg tgaactatga 9400

 tgaggatgag ttgtgtgtga aaatgcagct agccgacggg atctttgaga 9450

 ccctgatcaa agatactatt gatgttctga atcagatcag tgaaaagcag 9500

 gggagaatgc tactagtgtg acatcttgca aataaatcga acgctgagtg 9550

 ctaatgtgag tcctgggcct ttctgcctcc tgatgtacac ccatcgccat 9600

 catagcaaga gtgcttctgg accttgtact tattcttaaa gactaccagt 9650

 atggagttca taggacaatg tggtacacct ggtattacag cctttgcctt 9700

 tcgagactat ccactggatt aatgggttat tttcagtggg cagggttgca 9750

 cagtgtaatc ctacaccttt tgctaacacc cctactaggt cccagagggc 9800

 cagaaacacc tgacttacct ctgagtttag actagggtat cacttctttg 9850

 agtctgaagt caagtgagag aggtatagat aaatgcatca catcactttt 9900

 gaaatgtaat tctggtctat accatggaag tcataaatgg acattatagt 9950

 ctctaaacag tattaaaccc ttaaccactt ctaaaatagg caagctcaat 10000

 aatgtctgcc aacttcacat tctggagttt atttcatttc tttttgaaga 10050

 ccattttctt ccattattgt agttgagcag caccaagtgg actgtcaggc 10100

 taacaggaat aagtggtagc cttgctttct gagcaccatc taaagaattt 10150

 taaacctctg cattatgttt agtgttctct gtgtgggcat gaaaacaaag 10200

 aaatgcccct actgaagact gggctcaaag gaccaatgca gggctggttc 10250

 ttttacccct tggtttactc ctgcacttgt cttactcatt ctgaatctct 10300

 accagctgct cccagaatca cagatactca ggaccatctc aggcatccag 10350

 gcatggcaaa gtggaaataa ttcattttgg cctgcaaacc ttcaactccc 10400

 atctttcccc aagaagtcag agatgctgtt acttgaatga tttaggaaat 10450

 gagtgtgtgc accaaagaca aaaagatatt gtctattgtt tgtgtgcttg 10500

 ttttgcgcta tggaacattt tttaatttat tttaagataa attattaagt 10550

 tgaaaatgtg tgtccctatt cagaagtgaa agattcatct tgtaatagtt 10600

 aaacctccat cttgaagctt ctatggttca tagtctttgc acaggaacct 10650

 gtggttttaa caaaccaata cacatattga agaagtcatt ttaattcagt 10700

 gaaacgaaga tgggcttttc cagatcacct gcaatagcag cagtgggata 10750

 aaatgattta aaaacactgt acaatttaac tctgcctctc ttgcagcatt 10800

 gcttctcaca actattacct gcatctgaaa aaaaatctat agactccagc 10850

 tgctacatta gagcataaga gatgctctcc tgggacctca gtaccctgcc 10900

 ttcttgactg gtttccgttc atcagtcctg tccctcttca agtaatctag 10950

 aagaatgtgg atactcttag gcgtgaatgt aaatgcctta atattgaagg 11000

 tcctggttag aagcatgata caagacatct actggattca tatttacaaa 11050

 tatcctggaa tgttatagct tcaaagtata ttagaaaaac cccaaagatg 11100

 gtataatctt taagtgtgca cgttcgttta tttctgcatc ttccctccaa 11150

 acttgccttt gcatcttaaa tatttcacta tgcacactcc cattcctctt 11200

 gggtttcatc ttgtcgttta agaaatgtac tgaaataatc attggaatat 11250

 ttgcattttg cacaatgact ggtatgatag ctcttgacaa ataaggaaag 11300

 cactgaaatg ttgtgattgg gtctcgggaa atgctcagat tgatgtctta 11350

 ccagcatttc ttctgggctt gtgatgttga gctgtagtct tgtagccata 11400

 atgagcaaat tgactaagag aagcaaaggt ttcttggggt tattaaccag 11450

 tagtgtggaa atactagttt tatgtggcca aggaaaagca aagccttttc 11500

 ttttcagttt gtgttatttg gaagacagaa aaacatcttg tctacatcct 11550

 ttggctgttt gtaggatcac gttgtcctta cgatactgaa actttacagc 11600

 tgctgtaaat tttttataaa tgaatttcaa aatgttataa tgggactgta 11650

 ggttgttttt ctacatcttc attatttgga cctaaaacca gtttttaata 11700

 agaaagttta tctttactct ttctgaaatt atgactccag 11740

<210> 2852
<211> 3117
<212> PRT
<213> Homo sapien

<400> 2852
 Met Arg Ser Ser Lys Ser Lys Glu Val Pro Leu Pro Asn Pro Arg
   1               5                  10                  15

 Asn Ser Gln Ser Lys Asp Thr Val Gln Ala Asp Ile Thr Thr Ser
                  20                  25                  30

 Trp Asp Ala Leu Ser Gln Thr Lys Ala Ala Leu Arg His Ile Glu
                  35                  40                  45

 Asn Lys Leu Glu Val Ala Pro Thr Ser Thr Ala Val Cys Asp Ser
                  50                  55                  60

 Val Met Asp Thr Lys Lys Ser Ser Thr Ser Ala Thr Arg Lys Ile
                  65                  70                  75

 Ser Arg Lys Asp Gly Arg Tyr Leu Asp Asp Ser Trp Val Asn Ala
                  80                  85                  90

 Pro Ile Ser Lys Ser Thr Lys Ser Arg Lys Glu Lys Ser Arg Ser
                  95                 100                 105

 Pro Leu Arg Ala Thr Thr Leu Glu Gly Asn Val Lys Lys Asn Asn
                 110                 115                 120

 Arg Val Glu Phe Arg Glu Pro Leu Val Ser Tyr Arg Glu Ile His
                 125                 130                 135

 Gly Ala Pro Ser Asn Phe Ser Ser Ser His Leu Glu Ser Lys His
                 140                 145                 150

 Val Tyr Cys Val Asp Val Asn Glu Glu Lys Thr Glu Ser Gly Asn
                 155                 160                 165

 Trp Met Ile Gly Ser Arg Glu Glu Arg Asn Ile Arg Ser Cys Asp
                 170                 175                 180

 Phe Glu Ser Ser Gln Ser Ser Val Ile Asn Asp Thr Val Val Arg
                 185                 190                 195

 Phe Leu Asn Asp Arg Pro Ala Ile Asp Ala Leu Gln Asn Ser Glu
                 200                 205                 210

 Cys Leu Ile Arg Met Gly Ala Ser Met Arg Thr Glu Glu Glu Met
                 215                 220                 225

 Pro Asn Arg Thr Lys Gly Ser Glu Asn Asn Leu Lys Leu Ser Val
                 230                 235                 240

 Asn Asn Met Ala His Asp Thr Asp Pro Lys Ala Leu Arg Leu Thr
                 245                 250                 255

 Asp Ser Ser Pro Ser Ser Thr Ser Thr Ser Asn Ser Gln Arg Leu
                 260                 265                 270

 Asp Ile Leu Lys Arg Arg Gln His Asp Val Lys Leu Glu Lys Leu
                 275                 280                 285

 Lys Glu Arg Ile Arg Lys Gln Trp Glu His Ser Glu Glu Thr Asn
                 290                 295                 300

 Gly Arg Gly Gln Lys Leu Gly His Ile Asp His Pro Val Met Val
                 305                 310                 315

 Val Asn Val Asp Asn Ser Val Thr Ala Lys Val Arg Lys Val Ala
                 320                 325                 330

 Thr Ala Pro Pro Ala Pro Ala Tyr Lys Gly Phe Asn Pro Ser Glu
                 335                 340                 345

 Thr Lys Ile Arg Thr Pro Asp Gly Lys Val Trp Gln Glu Ala Glu
                 350                 355                 360

 Phe Gln Asn Met Ser Arg Glu Leu Tyr Arg Asp Leu Ala Leu His
                 365                 370                 375

 Phe Ala Asp Asp Ile Ser Ile Lys Glu Lys Pro Ala Glu Lys Ser
                 380                 385                 390

 Lys Glu Lys Lys Val Val Lys Pro Val Arg Lys Val Gln Lys Val
                 395                 400                 405

 Ala Gln Leu Ser Ser Thr Glu Cys Arg Thr Gly Ser Ser His Leu
                 410                 415                 420

 Ile Ser Thr Ser Ser Trp Arg Asp Gly Gln Lys Leu Val Lys Lys
                 425                 430                 435

 Ile Leu Gly Pro Ala Pro Arg Met Glu Pro Lys Glu Gln Arg Thr
                 440                 445                 450

 Ala Ser Ser Asp Arg Gly Gly Arg Arg Arg Thr Ala Lys Ser Gly
                 455                 460                 465

 Gly His Ile Gly Arg Ala Glu Ser Asp Pro Arg Leu Asp Val Leu
                 470                 475                 480

 His Arg His Leu Gln Arg Asn Ser Glu Arg Ser Arg Ser Lys Ser
                 485                 490                 495

 Arg Ser Glu Asn Asn Ile Lys Lys Leu Ala Ser Ser Leu Pro Asp
                 500                 505                 510

 Asn Lys Gln Glu Glu Asn Thr Ala Leu Asn Lys Asp Phe Leu Pro
                 515                 520                 525

 Ile Glu Ile Arg Gly Ile Leu Asp Asp Leu Gln Leu Asp Ser Thr
                 530                 535                 540

 Ala His Thr Ala Lys Gln Asp Thr Val Glu Leu Gln Asn Gln Lys
                 545                 550                 555

 Ser Ser Ala Pro Val His Ala Pro Arg Ser His Ser Pro Val Lys
                 560                 565                 570

 Arg Lys Pro Asp Lys Ile Thr Ala Asn Glu Asp Pro Pro Val Ile
                 575                 580                 585

 Ser Lys Arg Arg His Tyr Asp Thr Asp Glu Val Arg Gln Tyr Ile
                 590                 595                 600

 Val Arg Gln Gln Glu Glu Arg Lys Arg Lys Gln Asn Glu Glu Lys
                 605                 610                 615

 Lys Ala Gln Lys Glu Ala Thr Glu Gln Lys Asn Lys Arg Leu Gln
                 620                 625                 630

 Glu Leu Tyr Arg Lys Gln Lys Glu Ala Phe Thr Lys Val Lys Asn
                 635                 640                 645

 Val Pro Pro Ser Glu Pro Ser Ala Thr Arg Arg Leu Gln Glu Thr
                 650                 655                 660

 Tyr Ser Lys Leu Leu Leu Glu Lys Thr Leu Leu Glu Glu Pro Ser
                 665                 670                 675

 His Gln His Val Thr Gln Glu Thr Gln Ala Lys Pro Gly Tyr Gln
                 680                 685                 690

 Pro Ser Gly Glu Ser Asp Lys Glu Asn Lys Val Gln Glu Arg Pro
                 695                 700                 705

 Pro Ser Ala Ser Ser Ser Ser Asp Met Ser Leu Ser Glu Pro Pro
                 710                 715                 720

 Gln Pro Leu Ala Arg Lys Asp Leu Met Glu Ser Thr Trp Met Gln
                 725                 730                 735

 Pro Glu Arg Leu Ser Pro Gln Val His His Ser Gln Pro Gln Pro
                 740                 745                 750

 Phe Ala Gly Thr Ala Gly Ser Leu Leu Ser His Leu Leu Ser Leu
                 755                 760                 765

 Glu His Val Gly Ile Leu His Lys Asp Phe Glu Ser Ile Leu Pro
                 770                 775                 780

 Thr Arg Lys Asn His Asn Met Ala Ser Arg Pro Leu Thr Phe Thr
                 785                 790                 795

 Pro Gln Pro Tyr Val Thr Ser Pro Ala Ala Tyr Thr Asp Ala Leu
                 800                 805                 810

 Leu Lys Pro Ser Ala Ser Gln Tyr Lys Ser Lys Leu Asp Arg Ile
                 815                 820                 825

 Glu Ala Leu Lys Ala Thr Ala Ala Ser Leu Ser Ser Arg Ile Glu
                 830                 835                 840

 Ser Glu Ala Lys Lys Leu Ala Gly Ala Ser Ile Asn Tyr Gly Ser
                 845                 850                 855

 Ala Trp Asn Thr Glu Tyr Asp Val Gln Gln Ala Pro Gln Glu Asp
                 860                 865                 870

 Gly Pro Trp Thr Lys Ala Val Thr Pro Pro Val Lys Asp Asp Asn
                 875                 880                 885

 Glu Asp Val Phe Ser Ala Arg Ile Gln Lys Met Leu Gly Ser Cys
                 890                 895                 900

 Val Ser His Ala Thr Phe Asp Asp Asp Leu Pro Gly Val Gly Asn
                 905                 910                 915

 Leu Ser Glu Phe Lys Lys Leu Pro Glu Met Ile Arg Pro Gln Ser
                 920                 925                 930

 Ala Ile Ser Ser Phe Arg Val Arg Ser Pro Gly Pro Lys Pro Gln
                 935                 940                 945

 Gly Leu Leu Ala Gln Leu Cys Lys Arg Gln Thr Asp Ser Ser Ser
                 950                 955                 960

 Ser Asp Met Gln Ala Cys Ser Gln Asp Lys Ala Lys Ile Ser Leu
                 965                 970                 975

 Gly Ser Ser Ile Asp Ser Val Ser Glu Gly Pro Leu Leu Ser Glu
                 980                 985                 990

 Gly Ser Leu Ser Glu Glu Glu Gly Asp Gln Asp Gly Gln Pro Leu
                 995                1000                1005

 Leu Lys Val Ala Glu Ile Leu Lys Glu Lys Glu Phe Cys Pro Gly
                1010                1015                1020

 Glu Arg Asn Ser Tyr Glu Pro Ile Lys Glu Phe Gln Lys Glu Ala
                1025                1030                1035

 Glu Lys Phe Leu Pro Leu Phe Gly His Ile Gly Gly Thr Gln Ser
                1040                1045                1050

 Lys Gly Pro Trp Glu Glu Leu Ala Lys Gly Ser Pro His Ser Val
                1055                1060                1065

 Ile Asn Ile Phe Thr Lys Ser Tyr Gln Leu Tyr Gly Lys Gly Phe
                1070                1075                1080

 Glu Asp Lys Leu Asp Arg Gly Thr Ser Thr Ser Arg Pro Leu Asn
                1085                1090                1095

 Ala Thr Ala Thr Pro Leu Ser Gly Val Ser Tyr Glu Asp Asp Phe
                1100                1105                1110

 Val Ser Ser Pro Gly Thr Gly Thr Ser Thr Glu Lys Lys Ser Thr
                1115                1120                1125

 Leu Glu Pro His Ser Thr Leu Ser Pro Gln Glu Asp His Ser Asn
                1130                1135                1140

 Arg Lys Ser Ala Tyr Asp Pro Ser Ser Val Asp Val Thr Ser Gln
                1145                1150                1155

 His Ser Ser Gly Ala Gln Ser Ala Ala Ser Ser Arg Ser Ser Thr
                1160                1165                1170

 Ser Ser Lys Gly Lys Lys Gly Lys Lys Glu Lys Thr Glu Trp Leu
                1175                1180                1185

 Asp Ser Phe Thr Gly Asn Val Gln Asn Ser Leu Leu Asp Glu Glu
                1190                1195                1200

 Lys Ala Glu Arg Gly Ser His Gln Gly Lys Lys Ser Gly Thr Ser
                1205                1210                1215

 Ser Lys Leu Ser Val Lys Asp Phe Glu Gln Thr Leu Asp Thr Asp
                1220                1225                1230

 Ser Thr Leu Glu Asp Leu Ser Gly His Ser Val Ser Val Ser Ser
                1235                1240                1245

 Asp Lys Gly Arg Ser Gln Lys Thr Pro Thr Ser Pro Leu Ser Pro
                1250                1255                1260

 Ser Ser Gln Lys Ser Leu Gln Phe Asp Val Ala Gly Thr Ser Ser
                1265                1270                1275

 Glu Arg Ser Lys Ser Ser Val Met Pro Pro Thr Ile Thr Gly Phe
                1280                1285                1290

 Lys Pro Asn Ala Pro Leu Thr Asp Leu Asn Pro Ala Ala Ser Arg
                1295                1300                1305

 Thr Thr Thr Glu Asn Met Ala Pro Ile Pro Gly Ser Lys Arg Phe
                1310                1315                1320

 Ser Pro Ala Gly Leu His His Arg Met Ala Ala Glu Leu Ser Tyr
                1325                1330                1335

 Leu Asn Ala Ile Glu Glu Ser Val Arg Gln Leu Ser Asp Val Glu
                1340                1345                1350

 Arg Val Arg Gly Ile Ser Leu Ala Gln Gln Glu Ser Val Ser Leu
                1355                1360                1365

 Ala Gln Ile Ile Lys Ala Gln Gln Gln Arg His Glu Arg Asp Leu
                1370                1375                1380

 Ala Leu Leu Lys Leu Lys Ala Glu Gln Glu Ala Leu Glu Ser Gln
                1385                1390                1395

 Arg Gln Leu Glu Glu Thr Arg Asn Lys Ala Ala Gln Val His Ala
                1400                1405                1410

 Glu Ser Leu Gln Gln Val Val Gln Ser Gln Arg Glu Val Thr Glu
                1415                1420                1425

 Val Leu Gln Glu Ala Thr Cys Lys Ile Ala Ala Gln Gln Ser Glu
                1430                1435                1440

 Thr Ala Arg Leu Thr Thr Asp Ala Ala Arg Gln Ile Cys Glu Met
                1445                1450                1455

 Ala Glu Leu Thr Arg Thr His Ile Ser Asp Ala Val Val Ala Ser
                1460                1465                1470

 Gly Ala Pro Leu Ala Ile Leu Tyr Asp His Gln Arg Gln His Leu
                1475                1480                1485

 Pro Asp Phe Val Lys Gln Leu Arg Thr Arg Thr Glu Thr Asp Arg
                1490                1495                1500

 Lys Ser Pro Ser Val Ser Leu Ser Gln Ser Lys Glu Gly Thr Leu
                1505                1510                1515

 Asp Ser Lys His Gln Lys Tyr Ser Ala Ser Tyr Asp Ser Tyr Ser
                1520                1525                1530

 Glu Ser Ser Gly Tyr Lys Asn His Asp Arg Arg Ser Ser Ser Gly
                1535                1540                1545

 Ser Ser Arg Gln Glu Ser Pro Ser Val Pro Ser Cys Lys Glu Asn
                1550                1555                1560

 Glu Lys Lys Leu Asn Gly Glu Lys Ile Glu Ser Ser Ile Asp Glu
                1565                1570                1575

 Gln Val Gln Thr Ala Ala Asp Asp Ser Leu Arg Ser Asp Ser Val
                1580                1585                1590

 Pro Ser Leu Pro Asp Glu Lys Asp Ser Thr Ser Ile Ala Thr Glu
                1595                1600                1605

 Tyr Ser Leu Lys Phe Asp Glu Ser Met Thr Glu Asp Glu Ile Glu
                1610                1615                1620

 Glu Gln Ser Phe Arg Ser Leu Leu Pro Ser Glu Ser His Arg Arg
                1625                1630                1635

 Phe Asn Met Glu Lys Arg Arg Gly His His Asp Asp Ser Asp Glu
                1640                1645                1650

 Glu Ala Ser Pro Glu Lys Thr Thr Leu Ser Thr Ala Lys Glu Leu
                1655                1660                1665

 Asn Met Pro Phe Ser Gly Gly Gln Asp Ser Phe Ser Lys Phe Thr
                1670                1675                1680

 Met Glu Met Val Arg Gln Tyr Met Lys Glu Glu Glu Met Arg Ala
                1685                1690                1695

 Ala His Gln Ser Ser Leu Leu Arg Leu Arg Glu Lys Ala Leu Lys
                1700                1705                1710

 Glu Lys Thr Lys Ala Glu Leu Ala Trp Leu Glu His Gln Lys Lys
                1715                1720                1725

 His Leu Arg Asp Lys Gly Glu Asp Asp Lys Met Pro Pro Leu Arg
                1730                1735                1740

 Lys Lys Gln Arg Gly Leu Leu Leu Arg Leu Gln Gln Glu Lys Ala
                1745                1750                1755

 Glu Ile Lys Arg Leu Gln Glu Ala Asn Lys Ala Ala Arg Lys Glu
                1760                1765                1770

 Arg Gln Leu Ile Leu Lys Gln Gln Glu Glu Ile Glu Lys Ile Arg
                1775                1780                1785

 Gln Thr Thr Ile Lys Leu Gln Glu Lys Leu Lys Ser Ala Gly Glu
                1790                1795                1800

 Ser Lys Leu Asp Ser His Ser Asp Asp Asp Thr Lys Asp Asn Lys
                1805                1810                1815

 Ala Thr Ser Pro Gly Pro Thr Asp Leu Glu Thr Arg Ser Pro Ser
                1820                1825                1830

 Pro Ile Ser Ile Ser Ser Ser Glu Thr Ser Ser Ile Met Gln Lys
                1835                1840                1845

 Leu Lys Lys Met Arg Ser Arg Met Asp Glu Lys Phe Leu Thr Lys
                1850                1855                1860

 Arg Glu Gln Lys Leu Met Gln Arg Arg Gln His Ala Glu Glu Leu
                1865                1870                1875

 Leu Glu Trp Lys Arg Arg Leu Asp Ala Glu Glu Ala Glu Ile Arg
                1880                1885                1890

 Gln Met Glu Lys Gln Ala Leu Ala Ala Trp Asp Lys Glu Leu Ile
                1895                1900                1905

 Lys Pro Lys Thr Pro Lys Lys Glu Leu Glu Asp Gln Arg Thr Glu
                1910                1915                1920

 Gln Lys Glu Ile Ala Ser Glu Glu Glu Ser Pro Val Pro Leu Tyr
                1925                1930                1935

 Ser His Leu Asn Ser Glu Ser Ser Ile Pro Glu Glu Leu Gly Ser
                1940                1945                1950

 Pro Ala Val Glu Tyr Val Pro Ser Glu Ser Ile Gly Gln Glu Gln
                1955                1960                1965

 Pro Gly Ser Pro Asp His Ser Ile Leu Thr Glu Glu Met Ile Cys
                1970                1975                1980

 Ser Gln Glu Leu Glu Ser Ser Thr Ser Pro Ser Lys His Ser Leu
                1985                1990                1995

 Pro Lys Ser Cys Thr Ser Val Ser Lys Gln Glu Ser Ser Lys Gly
                2000                2005                2010

 Ser His Arg Thr Gly Gly Gln Cys His Leu Pro Ile Lys Ser His
                2015                2020                2025

 Gln His Cys Tyr Ser Trp Ser Asp Glu Ser Leu Ser Met Thr Gln
                2030                2035                2040

 Ser Glu Thr Thr Ser Asp Gln Ser Asp Ile Glu Gly Arg Ile Arg
                2045                2050                2055

 Ala Leu Lys Asp Glu Leu Arg Lys Arg Lys Ser Val Val Asn Gln
                2060                2065                2070

 Leu Lys Lys Glu Gln Lys Lys Arg Gln Lys Glu Arg Leu Lys Ala
                2075                2080                2085

 Gln Glu Ala Ser Leu Ile Lys Gln Leu Glu Ser Tyr Asp Glu Phe
                2090                2095                2100

 Ile Lys Lys Thr Glu Ala Glu Leu Ser Gln Asp Leu Glu Thr Ser
                2105                2110                2115

 Pro Thr Ala Lys Pro Gln Ile Lys Thr Leu Ser Ser Ala Ser Glu
                2120                2125                2130

 Lys Pro Lys Ile Lys Pro Leu Thr Pro Leu His Arg Ser Glu Thr
                2135                2140                2145

 Ala Lys Asn Trp Lys Ser Leu Thr Glu Ser Glu Arg Ser Arg Gly
                2150                2155                2160

 Ser Leu Glu Pro Ile Ala Glu His Val Asp Ala Ser Leu Ser Gly
                2165                2170                2175

 Ser Glu Arg Ser Val Ser Glu Arg Ser Leu Ser Ala Tyr Ala Lys
                2180                2185                2190

 Arg Val Asn Glu Trp Asp Ser Arg Thr Glu Asp Phe Gln Thr Pro
                2195                2200                2205

 Ser Pro Val Leu Arg Ser Ser Arg Lys Ile Arg Glu Glu Ser Gly
                2210                2215                2220

 Asp Ser Leu Glu Asn Val Pro Ala Leu His Leu Leu Lys Glu Leu
                2225                2230                2235

 Asn Ala Thr Ser Arg Ile Leu Asp Met Ser Asp Gly Lys Val Gly
                2240                2245                2250

 Glu Ser Ser Lys Lys Ser Glu Ile Lys Glu Ile Glu Tyr Thr Lys
                2255                2260                2265

 Leu Lys Lys Ser Lys Ile Glu Asp Ala Phe Ser Lys Glu Gly Lys
                2270                2275                2280

 Ser Asp Val Leu Leu Lys Leu Val Leu Glu Gln Gly Asp Ser Ser
                2285                2290                2295

 Glu Ile Leu Ser Lys Lys Asp Leu Pro Leu Asp Ser Glu Asn Val
                2300                2305                2310

 Gln Lys Asp Leu Val Gly Leu Ala Ile Glu Asn Leu His Lys Ser
                2315                2320                2325

 Glu Glu Met Leu Lys Glu Arg Gln Ser Asp Gln Asp Met Asn His
                2330                2335                2340

 Ser Pro Asn Ile Gln Ser Gly Lys Asp Ile His Glu Gln Lys Asn
                2345                2350                2355

 Thr Lys Glu Lys Asp Leu Ser Trp Ser Glu His Leu Phe Ala Pro
                2360                2365                2370

 Lys Glu Ile Pro Tyr Ser Glu Asp Phe Glu Val Ser Ser Phe Lys
                2375                2380                2385

 Lys Glu Ile Ser Ala Glu Leu Tyr Lys Asp Asp Phe Glu Val Ser
                2390                2395                2400

 Ser Leu Leu Ser Leu Arg Lys Asp Ser Gln Ser Cys Arg Asp Lys
                2405                2410                2415

 Pro Gln Pro Met Arg Ser Ser Thr Ser Gly Ala Thr Ser Phe Gly
                2420                2425                2430

 Ser Asn Glu Glu Ile Ser Glu Cys Leu Ser Glu Lys Ser Leu Ser
                2435                2440                2445

 Ile His Ser Asn Val His Ser Asp Arg Leu Leu Glu Leu Lys Ser
                2450                2455                2460

 Pro Thr Glu Leu Met Lys Ser Lys Glu Arg Ser Asp Val Glu His
                2465                2470                2475

 Glu Gln Gln Val Thr Glu Ser Pro Ser Leu Ala Ser Val Pro Thr
                2480                2485                2490

 Ala Asp Glu Leu Phe Asp Phe His Ile Gly Asp Arg Val Leu Ile
                2495                2500                2505

 Gly Asn Val Gln Pro Gly Ile Leu Arg Phe Lys Gly Glu Thr Ser
                2510                2515                2520

 Phe Ala Lys Gly Phe Trp Ala Gly Val Glu Leu Asp Lys Pro Glu
                2525                2530                2535

 Gly Asn Asn Asn Gly Thr Tyr Asp Gly Ile Ala Tyr Phe Glu Cys
                2540                2545                2550

 Lys Glu Lys His Gly Ile Phe Ala Pro Pro Gln Lys Ile Ser His
                2555                2560                2565

 Ile Pro Glu Asn Phe Asp Asp Tyr Val Asp Ile Asn Glu Asp Glu
                2570                2575                2580

 Asp Cys Tyr Ser Asp Glu Arg Tyr Gln Cys Tyr Asn Gln Glu Gln
                2585                2590                2595

 Asn Asp Thr Glu Gly Pro Lys Asp Arg Glu Lys Asp Val Ser Glu
                2600                2605                2610

 Tyr Phe Tyr Glu Lys Ser Leu Pro Ser Val Asn Asp Ile Glu Ala
                2615                2620                2625

 Ser Val Asn Arg Ser Arg Ser Leu Lys Ile Glu Thr Asp Asn Val
                2630                2635                2640

 Gln Asp Ile Ser Gly Val Leu Glu Ala His Val His Gln Gln Ser
                2645                2650                2655

 Ser Val Asp Ser Gln Ile Ser Ser Lys Glu Asn Lys Asp Leu Ile
                2660                2665                2670

 Ser Asp Ala Thr Glu Lys Val Ser Ile Ala Ala Glu Asp Asp Thr
                2675                2680                2685

 Leu Asp Asn Thr Phe Ser Glu Glu Leu Glu Lys Gln Gln Gln Phe
                2690                2695                2700

 Thr Glu Glu Glu Asp Asn Leu Tyr Ala Glu Ala Ser Glu Lys Leu
                2705                2710                2715

 Cys Thr Pro Leu Leu Asp Leu Leu Thr Arg Glu Lys Asn Gln Leu
                2720                2725                2730

 Glu Ala Gln Leu Lys Ser Ser Leu Asn Glu Glu Lys Lys Ser Lys
                2735                2740                2745

 Gln Gln Leu Glu Lys Ile Ser Leu Leu Thr Asp Ser Leu Leu Lys
                2750                2755                2760

 Val Phe Val Lys Asp Thr Val Asn Gln Leu Gln Gln Ile Lys Lys
                2765                2770                2775

 Thr Arg Asp Glu Lys Ile Gln Leu Ser Asn Gln Glu Leu Leu Gly
                2780                2785                2790

 Asp Asp Gln Lys Lys Val Thr Pro Gln Asp Leu Ser Gln Asn Val
                2795                2800                2805

 Glu Glu Gln Ser Pro Ser Ile Ser Gly Cys Phe Leu Ser Ser Glu
                2810                2815                2820

 Leu Glu Asp Glu Lys Glu Glu Ile Ser Ser Pro Asp Met Cys Pro
                2825                2830                2835

 Arg Pro Glu Ser Pro Val Phe Gly Ala Ser Gly Gln Glu Glu Leu
                2840                2845                2850

 Ala Lys Arg Leu Ala Glu Leu Glu Leu Ser Arg Glu Phe Leu Ser
                2855                2860                2865

 Ala Leu Gly Asp Asp Gln Asp Trp Phe Asp Glu Asp Phe Gly Leu
                2870                2875                2880

 Ser Ser Ser His Lys Ile Gln Lys Asn Lys Ala Glu Glu Thr Ile
                2885                2890                2895

 Val Pro Leu Met Ala Glu Pro Lys Arg Val Thr Gln Gln Pro Cys
                2900                2905                2910

 Glu Thr Leu Leu Ala Val Pro His Thr Ala Glu Glu Val Glu Ile
                2915                2920                2925

 Leu Val His Asn Ala Ala Glu Glu Leu Trp Lys Trp Lys Glu Leu
                2930                2935                2940

 Gly His Asp Leu His Ser Ile Ser Ile Pro Thr Lys Leu Leu Gly
                2945                2950                2955

 Cys Ala Ser Lys Gly Leu Asp Ile Glu Ser Thr Ser Lys Arg Val
                2960                2965                2970

 Tyr Lys Gln Ala Val Phe Asp Leu Thr Lys Glu Ile Phe Glu Glu
                2975                2980                2985

 Ile Phe Ala Glu Asp Pro Asn Leu Asn Gln Pro Val Trp Met Lys
                2990                2995                3000

 Pro Cys Arg Ile Asn Ser Ser Tyr Phe Arg Arg Val Lys Asn Pro
                3005                3010                3015

 Asn Asn Leu Asp Glu Ile Lys Ser Phe Ile Ala Ser Glu Val Leu
                3020                3025                3030

 Lys Leu Phe Ser Leu Lys Lys Glu Pro Asn His Lys Thr Asp Trp
                3035                3040                3045

 Gln Lys Met Met Lys Phe Gly Arg Lys Lys Arg Asp Arg Val Asp
                3050                3055                3060

 His Ile Leu Val Gln Glu Leu His Glu Glu Glu Ala Gln Trp Val
                3065                3070                3075

 Asn Tyr Asp Glu Asp Glu Leu Cys Val Lys Met Gln Leu Ala Asp
                3080                3085                3090

 Gly Ile Phe Glu Thr Leu Ile Lys Asp Thr Ile Asp Val Leu Asn
                3095                3100                3105

 Gln Ile Ser Glu Lys Gln Gly Arg Met Leu Leu Val
                3110                3115

<210> 2853
<211> 3139
<212> DNA
<213> Homo sapien

<400> 2853
 cagagagaga cacaggaaca agaacagcaa agggtagagc agacctgcgc 50

 caggggcgca caacggccgt gtccacctcc cggccccaag atggtgcttc 100

 ccacaggcag ccacgcgtag cagccagaga cagctccaga catgtggctc 150

 ttcttcggga tcactggatt gctgacggca gccctctcag gtcatccatc 200

 tccagcccca cctgaccagc tcaacaccag cagtgcagag agtgagctct 250

 gggagccagg ggagcggctt ccggtccgtc tgacaaacgg gagcagcagc 300

 tgcagcggga cggtggaggt gcggctcgag gcgtcctggg agcccgcgtg 350

 cggggcgctc tgggacagcc gcgccgccga ggccgtgtgc cgagcactgg 400

 gctgcggcgg ggcggaggcc gcctctcagc tcgccccgcc gacccctgag 450

 ctgccgcccc cgcctgcagc cgggaacacc agcgtagcag ctaatgccac 500

 tctggccggg gcgcccgccc tcctgtgcag cggcgccgag tggcggctct 550

 gcgaggtggt ggagcacgcg tgccgcagcg acgggaggcg ggcccgtgtc 600

 acctgtgcag agaaccgcgc gctgcgcctg gtggacggtg gcggcgcctg 650

 cgccggccgc gtggagatgc tggagcatgg cgagtgggga tcagtgtgcg 700

 atgacacttg ggacctggag gacgcccacg tggtgtgcag gcaactgggc 750

 tgcggctggg cagtccaggc cctgcccggc ttgcacttca cgcccggccg 800

 cgggcctatc caccgggacc aggtgaactg ctcgggggcc gaagcttacc 850

 tgtgggactg cccggggctg ccaggacagc actactgcgg ccacaaagag 900

 gacgcgggcg cggtgtgctc agagcaccag tcctggcgcc tgacaggggg 950

 cgctgaccgc tgcgaggggc aggtggaggt acacttccga ggggtctgga 1000

 acacagtgtg tgacagtgag tggtacccat cggaggccaa ggtgctctgc 1050

 cagtccttgg gctgtggaac tgcggttgag aggcccaagg ggctgcccca 1100

 ctccttgtcc ggcaggatgt actactcatg caatggggag gagctcaccc 1150

 tctccaactg ctcctggcgg ttcaacaact ccaacctctg cagccagtcg 1200

 ctggcagcca gggtcctctg ctcagcttcc cggagtttgc acaatctgtc 1250

 cactcccgaa gtccctgcaa gtgttcagac agtcactata gaatcttctg 1300

 tgacagtgaa aatagagaac aaggaatctc gggagctaat gctcctcatc 1350

 ccctccatcg ttctgggaat tctcctcctt ggctccctca tcttcatagc 1400

 cttcatcctc ttgagaatta aaggaaaata tgccctcccc gtaatggtga 1450

 accaccagca cctacccacc accatcccgg cagggagcaa tagctatcaa 1500

 ccggtcccca tcaccatccc caaagaagtt ttcatgctgc ccatccaggt 1550

 ccaggccccg ccccctgagg actcagactc tggctcggac tcagactatg 1600

 agcactatga cttcagcgcc cagcctcctg tggccctgac caccttctac 1650

 aattcccagc ggcatcgggt cacagatgag gaggtccagc aaagcaggtt 1700

 ccagatgcca cccttggagg aaggacttga agagttgcat gcctcccaca 1750

 tcccaactgc caaccctgga cactgcatta cagacccgcc atccctgggc 1800

 cctcagtatc acccgaggag caacagtgag tcgagcacct cttcagggga 1850

 ggattactgc aatagtccca aaagcaagct gcctccatgg aacccccagg 1900

 tgttttcttc agagaggagt tccttcctgg agcagccccc aaacttggag 1950

 ctggccggca cccagccagc cttttcaggg cccccggctg atgacagctc 2000

 cagcacctca tccggggagt ggtaccagaa cttccagccg aggctcctgg 2050

 ggtggctctg accctctggc ctcctgctct acctactccc tttccccttt 2100

 cccaccctcc cagctcacct ccccatggag ctgagaggcc tcccttggag 2150

 agatggaagg aaacgttata ccttgtaccc ctcggtctcc atccatcaag 2200

 ccaaacctgc tgccacagcc ctcccccggc cccagatagc agccccaggg 2250

 aggatgctgc ctccaagagg tgtgagccct ctgtctcggg gatgaacaag 2300

 cagagtctgg gctacctctt gacagctggt ggaggggagt tggggagctg 2350

 gactggatga ctctggaggc cccttccaaa cctcaagtgt ccggcgcttt 2400

 gattgcctga gtttctgaca cttcagggcc cagaggtcct gcgaggggca 2450

 gaactggacc cccatgccag tgctgctgca ggagggccca tatactaggg 2500

 tctgctgagc tgttgtcact gatcggtggg cgctgggggg gtagggtagc 2550

 acaccagctg tcccaggctt tgctccgggc ggtaactgca cttgggcagg 2600

 gaatatagcc ttcctgggca caactagctg acaatgacag gttgactgtg 2650

 tacccccaac caaggagctg gggcccaagg ccagtcctgc cccagagaca 2700

 ctccaagtcc gccaggggca cagaccagtt ctgcagtgac tgtccctgga 2750

 caatgggtct ttattctgag tttcctatgg tttacaaaga gggccccagc 2800

 ccagccccac cacagatccc agagataggg gcccagtctc catgggggca 2850

 aggagcatag agatgttttc caggaagggg ctcagaagct gcactaggcc 2900

 ccgagtcccc atgtgtctcc ttgaattgat gaggatgctc ctgggaggga 2950

 tgcgtgacta tgtggtgttg cacccggggc tgcaaacgtc tccgtgcagc 3000

 ccccagagag aggcccatgg gctcagacca ggctttgttg tcctgctctg 3050

 agtatcctga gattaaactg aattgctgaa tgaaaaaaaa aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 3139

<210> 2854
<211> 639
<212> PRT
<213> Homo sapien

<400> 2854
 Met Trp Leu Phe Phe Gly Ile Thr Gly Leu Leu Thr Ala Ala Leu
   1               5                  10                  15

 Ser Gly His Pro Ser Pro Ala Pro Pro Asp Gln Leu Asn Thr Ser
                  20                  25                  30

 Ser Ala Glu Ser Glu Leu Trp Glu Pro Gly Glu Arg Leu Pro Val
                  35                  40                  45

 Arg Leu Thr Asn Gly Ser Ser Ser Cys Ser Gly Thr Val Glu Val
                  50                  55                  60

 Arg Leu Glu Ala Ser Trp Glu Pro Ala Cys Gly Ala Leu Trp Asp
                  65                  70                  75

 Ser Arg Ala Ala Glu Ala Val Cys Arg Ala Leu Gly Cys Gly Gly
                  80                  85                  90

 Ala Glu Ala Ala Ser Gln Leu Ala Pro Pro Thr Pro Glu Leu Pro
                  95                 100                 105

 Pro Pro Pro Ala Ala Gly Asn Thr Ser Val Ala Ala Asn Ala Thr
                 110                 115                 120

 Leu Ala Gly Ala Pro Ala Leu Leu Cys Ser Gly Ala Glu Trp Arg
                 125                 130                 135

 Leu Cys Glu Val Val Glu His Ala Cys Arg Ser Asp Gly Arg Arg
                 140                 145                 150

 Ala Arg Val Thr Cys Ala Glu Asn Arg Ala Leu Arg Leu Val Asp
                 155                 160                 165

 Gly Gly Gly Ala Cys Ala Gly Arg Val Glu Met Leu Glu His Gly
                 170                 175                 180

 Glu Trp Gly Ser Val Cys Asp Asp Thr Trp Asp Leu Glu Asp Ala
                 185                 190                 195

 His Val Val Cys Arg Gln Leu Gly Cys Gly Trp Ala Val Gln Ala
                 200                 205                 210

 Leu Pro Gly Leu His Phe Thr Pro Gly Arg Gly Pro Ile His Arg
                 215                 220                 225

 Asp Gln Val Asn Cys Ser Gly Ala Glu Ala Tyr Leu Trp Asp Cys
                 230                 235                 240

 Pro Gly Leu Pro Gly Gln His Tyr Cys Gly His Lys Glu Asp Ala
                 245                 250                 255

 Gly Ala Val Cys Ser Glu His Gln Ser Trp Arg Leu Thr Gly Gly
                 260                 265                 270

 Ala Asp Arg Cys Glu Gly Gln Val Glu Val His Phe Arg Gly Val
                 275                 280                 285

 Trp Asn Thr Val Cys Asp Ser Glu Trp Tyr Pro Ser Glu Ala Lys
                 290                 295                 300

 Val Leu Cys Gln Ser Leu Gly Cys Gly Thr Ala Val Glu Arg Pro
                 305                 310                 315

 Lys Gly Leu Pro His Ser Leu Ser Gly Arg Met Tyr Tyr Ser Cys
                 320                 325                 330

 Asn Gly Glu Glu Leu Thr Leu Ser Asn Cys Ser Trp Arg Phe Asn
                 335                 340                 345

 Asn Ser Asn Leu Cys Ser Gln Ser Leu Ala Ala Arg Val Leu Cys
                 350                 355                 360

 Ser Ala Ser Arg Ser Leu His Asn Leu Ser Thr Pro Glu Val Pro
                 365                 370                 375

 Ala Ser Val Gln Thr Val Thr Ile Glu Ser Ser Val Thr Val Lys
                 380                 385                 390

 Ile Glu Asn Lys Glu Ser Arg Glu Leu Met Leu Leu Ile Pro Ser
                 395                 400                 405

 Ile Val Leu Gly Ile Leu Leu Leu Gly Ser Leu Ile Phe Ile Ala
                 410                 415                 420

 Phe Ile Leu Leu Arg Ile Lys Gly Lys Tyr Ala Leu Pro Val Met
                 425                 430                 435

 Val Asn His Gln His Leu Pro Thr Thr Ile Pro Ala Gly Ser Asn
                 440                 445                 450

 Ser Tyr Gln Pro Val Pro Ile Thr Ile Pro Lys Glu Val Phe Met
                 455                 460                 465

 Leu Pro Ile Gln Val Gln Ala Pro Pro Pro Glu Asp Ser Asp Ser
                 470                 475                 480

 Gly Ser Asp Ser Asp Tyr Glu His Tyr Asp Phe Ser Ala Gln Pro
                 485                 490                 495

 Pro Val Ala Leu Thr Thr Phe Tyr Asn Ser Gln Arg His Arg Val
                 500                 505                 510

 Thr Asp Glu Glu Val Gln Gln Ser Arg Phe Gln Met Pro Pro Leu
                 515                 520                 525

 Glu Glu Gly Leu Glu Glu Leu His Ala Ser His Ile Pro Thr Ala
                 530                 535                 540

 Asn Pro Gly His Cys Ile Thr Asp Pro Pro Ser Leu Gly Pro Gln
                 545                 550                 555

 Tyr His Pro Arg Ser Asn Ser Glu Ser Ser Thr Ser Ser Gly Glu
                 560                 565                 570

 Asp Tyr Cys Asn Ser Pro Lys Ser Lys Leu Pro Pro Trp Asn Pro
                 575                 580                 585

 Gln Val Phe Ser Ser Glu Arg Ser Ser Phe Leu Glu Gln Pro Pro
                 590                 595                 600

 Asn Leu Glu Leu Ala Gly Thr Gln Pro Ala Phe Ser Gly Pro Pro
                 605                 610                 615

 Ala Asp Asp Ser Ser Ser Thr Ser Ser Gly Glu Trp Tyr Gln Asn
                 620                 625                 630

 Phe Gln Pro Arg Leu Leu Gly Trp Leu
                 635

<210> 2855
<211> 1487
<212> DNA
<213> Homo sapien

<400> 2855
 ctagcactct gacctagcag tcaacatgaa ggctctcatt gttctggggc 50

 ttgtcctcct ttctgttacg gtccagggca aggtctttga aaggtgtgag 100

 ttggccagaa ctctgaaaag attgggaatg gatggctaca ggggaatcag 150

 cctagcaaac tggatgtgtt tggccaaatg ggagagtggt tacaacacac 200

 gagctacaaa ctacaatgct ggagacagaa gcactgatta tgggatattt 250

 cagatcaata gccgctactg gtgtaatgat ggcaaaaccc caggagcagt 300

 taatgcctgt catttatcct gcagtgcttt gctgcaagat aacatcgctg 350

 atgctgtagc ttgtgcaaag agggttgtcc gtgatccaca aggcattaga 400

 gcatgggtgg catggagaaa tcgttgtcaa aacagagatg tccgtcagta 450

 tgttcaaggt tgtggagtgt aactccagaa ttttccttct tcagctcatt 500

 ttgtctctct cacattaagg gagtaggaat taagtgaaag gtcacactac 550

 cattatttcc ccttcaaaca aataatattt ttacagaagc aggagcaaaa 600

 tatggccttt cttctaagag atataatgtt cactaatgtg gttattttac 650

 attaagccta caacattttt cagtttgcaa atagaactaa tactggtgaa 700

 aatttaccta aaaccttggt tatcaaatac atctccagta cattccgttc 750

 tttttttttt ttgagacagt ctcgctctgt cgcccaggct ggagtgcagt 800

 ggcgcaatct cggctcactg caacctccac ctcccgggtt cacgccattc 850

 tcctgcctca gcctcccgag tagctgggat tacgggcgcc cgccaccacg 900

 cccggctaat tttttgtatt tttagtagag acagggtttc accgtgttag 950

 ccaggatggt ctcgatctcc tgaccttgtg atccacccac ctcggcctcc 1000

 caaagtgctg ggattacagg cgtgagccac tgcgcccggc cacattcagt 1050

 tcttatcaaa gaaataaccc agacttaatc ttgaatgata cgattatgcc 1100

 caatattaag taaaaaatat aagaaaaggt tatcttaaat agatcttagg 1150

 caaaatacca gctgatgaag gcatctgatg ccttcatctg ttcagtcatc 1200

 tccaaaaaca gtaaaaataa ccactttttg ttgggcaata tgaaattttt 1250

 aaaggagtag aataccaaat gatagaaaca gactgcctga attgagaatt 1300

 ttgatttctt aaagtgtgtt tctttctaaa ttgctgttcc ttaatttgat 1350

 taatttaatt catgtattat gattaaatct gaggcagatg agcttacaag 1400

 tattgaaata attactaatt aatcacaaat gtgaagttat gcatgatgta 1450

 aaaaatacaa acattctaat taaaggcttt gcaacac 1487

<210> 2856
<211> 148
<212> PRT
<213> Homo sapien

<400> 2856
 Met Lys Ala Leu Ile Val Leu Gly Leu Val Leu Leu Ser Val Thr
   1               5                  10                  15

 Val Gln Gly Lys Val Phe Glu Arg Cys Glu Leu Ala Arg Thr Leu
                  20                  25                  30

 Lys Arg Leu Gly Met Asp Gly Tyr Arg Gly Ile Ser Leu Ala Asn
                  35                  40                  45

 Trp Met Cys Leu Ala Lys Trp Glu Ser Gly Tyr Asn Thr Arg Ala
                  50                  55                  60

 Thr Asn Tyr Asn Ala Gly Asp Arg Ser Thr Asp Tyr Gly Ile Phe
                  65                  70                  75

 Gln Ile Asn Ser Arg Tyr Trp Cys Asn Asp Gly Lys Thr Pro Gly
                  80                  85                  90

 Ala Val Asn Ala Cys His Leu Ser Cys Ser Ala Leu Leu Gln Asp
                  95                 100                 105

 Asn Ile Ala Asp Ala Val Ala Cys Ala Lys Arg Val Val Arg Asp
                 110                 115                 120

 Pro Gln Gly Ile Arg Ala Trp Val Ala Trp Arg Asn Arg Cys Gln
                 125                 130                 135

 Asn Arg Asp Val Arg Gln Tyr Val Gln Gly Cys Gly Val
                 140                 145

<210> 2857
<211> 1157
<212> DNA
<213> Homo sapien

<400> 2857
 ctggtgttta tccgtcactc gccgaggttc cttgggtcat ggtgccagcc 50

 tgactgagaa gaggacgctc ccgggagacg aatgaggaac cacctcctcc 100

 tactgttcaa gtacaggggc ctggtccgca aagggaagaa aagcaaaaga 150

 cgaaaatggc taaattcgtg atccgcccag ccactgccgc cgactgcagt 200

 gacatactgc ggctgatcaa ggagctggct aaatatgaat acatggaaga 250

 acaagtaatc ttaactgaaa aagatctgct agaagatggt tttggagagc 300

 acccctttta ccactgcctg gttgcagaag tgccgaaaga gcactggact 350

 ccggaaggtt acagtctcta gcttcgccat gtacatggcc cttccgtgta 400

 catggatggg cggggaggta actaaaagat cctttacaca ataaagtaga 450

 tgatcatgat aaatgaggac acagcattgt tggttttgcc atgtactatt 500

 ttacctatga cccgtggatt ggcaagttat tgtatcttga ggacttcttc 550

 gtgatgagtg attatagagg ctttggcata ggatcagaaa ttctgaagaa 600

 tctaagccag gttgcaatga ggtgtcgctg cagcagcatg cacttcttgg 650

 tagcagaatg gaatgaacca tccatcaact tctataaaag aagaggtgct 700

 tctgatctgt ccagtgaaga gggttggaga ctgttcaaga tcgacaagga 750

 gtacttgcta aaaatggcaa cagaggagtg aggagtgctg ctgtagatga 800

 caacctccat tctattttag aataaattcc caacttctct tgctttctat 850

 gctgtttgta gtgaaataat agaatgagca cccattccaa agctttatta 900

 ccagtggcgt tgttgcatgt ttgaaatgag gtctgtttaa agtggcaatc 950

 tcagatgcag tttggagagt cagatctttc tccttgaata tctttcgata 1000

 aacaacaagg tggtgtgatc ttaatatatt tgaaaaaaac ttcattctcg 1050

 tgagtcattt aaatgtgtac aatgtacaca ctggtactta gagtttctgt 1100

 ttgattcttt tttaataaac tactctttga tttaaaaaaa aaaaaaaaaa 1150

 aaaaaaa 1157

<210> 2858
<211> 75
<212> PRT
<213> Homo sapien

<400> 2858
 Met Ser Asp Tyr Arg Gly Phe Gly Ile Gly Ser Glu Ile Leu Lys
   1               5                  10                  15

 Asn Leu Ser Gln Val Ala Met Arg Cys Arg Cys Ser Ser Met His
                  20                  25                  30

 Phe Leu Val Ala Glu Trp Asn Glu Pro Ser Ile Asn Phe Tyr Lys
                  35                  40                  45

 Arg Arg Gly Ala Ser Asp Leu Ser Ser Glu Glu Gly Trp Arg Leu
                  50                  55                  60

 Phe Lys Ile Asp Lys Glu Tyr Leu Leu Lys Met Ala Thr Glu Glu
                  65                  70                  75

<210> 2859
<211> 774
<212> DNA
<213> Homo sapien

<400> 2859
 cagctgtgtg gacagtgcca cacgccctcc tggacaacga cggctcttgc 50

 gtgcattttc cagtgttgct tttgtcagag aggccagcag agccacggtt 100

 cttccagaac cagccctgag ctgagtgagg agtgcccagg agagatggtg 150

 aaaatgacaa agtccaaaac tttccaagcg tatctgccga actgtcaccg 200

 aacgtacagc tgtatccact gcagagcaca cctggccaat catgacgagc 250

 tcatctccaa gtcctttcag gggagccagg gacgcgccta cctcttcaat 300

 tccgtggtga acgtgggctg cggccctgca gaggagaggg tccttctcac 350

 cgggctgcat gcggttgccg acatctactg cgagaactgc aagaccacgc 400

 tcgggtggaa atacgagcat gcctttgaga gcagtcagaa atataaggaa 450

 ggaaaattca tcattgagct tgctcatatg atcaaagaca atggctggga 500

 gtaatgtgcg aactttccct tctccttcga atgctgtttt gtgaaagaaa 550

 ctgtgaatgt aatggaaacg taggagcatc tggtgacagc ctttcttgcc 600

 ctctgacctc aaaggctagc tgcgcatagc tcttgacact cccggccatc 650

 tctgtgggta aggtgtccct cggatctgtc ctcttcgtgt acacagttgt 700

 ttctgaaaat tttcaatgag ctttttctaa cttctcaagt tctagagaaa 750

 gaattaacca actgatgact taaa 774

<210> 2860
<211> 119
<212> PRT
<213> Homo sapien

<400> 2860
 Met Val Lys Met Thr Lys Ser Lys Thr Phe Gln Ala Tyr Leu Pro
   1               5                  10                  15

 Asn Cys His Arg Thr Tyr Ser Cys Ile His Cys Arg Ala His Leu
                  20                  25                  30

 Ala Asn His Asp Glu Leu Ile Ser Lys Ser Phe Gln Gly Ser Gln
                  35                  40                  45

 Gly Arg Ala Tyr Leu Phe Asn Ser Val Val Asn Val Gly Cys Gly
                  50                  55                  60

 Pro Ala Glu Glu Arg Val Leu Leu Thr Gly Leu His Ala Val Ala
                  65                  70                  75

 Asp Ile Tyr Cys Glu Asn Cys Lys Thr Thr Leu Gly Trp Lys Tyr
                  80                  85                  90

 Glu His Ala Phe Glu Ser Ser Gln Lys Tyr Lys Glu Gly Lys Phe
                  95                 100                 105

 Ile Ile Glu Leu Ala His Met Ile Lys Asp Asn Gly Trp Glu
                 110                 115

<210> 2861
<211> 1280
<212> DNA
<213> Homo sapien

<400> 2861
 gcggccgccg tggccaggca acctatgggt accaccgggt tctcgcgggt 50

 cttgcgaacg aacttttcct tgaaactctc tggattcctg taaacagtgg 100

 ggctcagccc ctcaatgact ggaggcttcg atggttcaaa ggggacctcc 150

 ggaatcacag ggccgggagt cgccatgtcc gggccacagc agcaggagaa 200

 aatcgggact ccgacctcag cctcccggtg aaggtcatga aaggggcggg 250

 gaaacgaata aattgagcct tgtacgcagg cgcaaatgct cgttgcatcc 300

 tgggagtcgt agtgctcagc acggtagtgc tacaaaagga ctacatttcc 350

 ccaaatgccc gcaaagcctt gtgcacgcct tccggaagga gtttgttaca 400

 cgaggtctga gagacagagg cagcgtgttt gagctgctgg tgcggtggtc 450

 agcgcgatgc ccaaggccaa gggcaaaacc cggaggcaga agtttggtta 500

 cagtgtcaac cgaaagcgtc tgaaccggaa tgctcgacgg aaggcagcgc 550

 gcggaatcga atgctcccac atccgacatg cctgggacca cgctaaatcg 600

 gtacggcaga acctggccga gatggggttg gctgtggacc ccaacagggc 650

 ggtgcccctc cgtaagagaa aggtgaaggc catggaggtg gacatagagg 700

 agaggcctaa agagcttgta cggaagccct atgtgctgaa tgacctggag 750

 gcagaagcca gccttccaga aaagaaagga aatactctgt ctcgggacct 800

 cattgactat gtacgctaca tggtagagaa ccacggggag gactataagg 850

 ccatggcccg tgatgagaag aattactatc aagatacccc aaaacagatt 900

 cggagtaaga tcaacgtcta taaacgcttt tacccagcag agtggcaaga 950

 cttcctcgat tctttgcaga agaggaagat ggaggtggag taactggttt 1000

 acatcacagc tgccccaggc tgaggcgtcc cccggaccag tgaagctgga 1050

 gccagggtgt aaggcaagga ggtgctgtgt ggctccagag gggctggcca 1100

 ggtcccatgg aatcagaagg ttacacacac acgtgcacac tccccgctct 1150

 ggggaaggaa ctgttctcag aggctccaat ttatattcat ctgggggttc 1200

 acggaaaagc cagaacctgc tgttttcagg gtgggtgatg taaatatagt 1250

 gtgtacataa taaagcaaat atattttaaa 1280

<210> 2862
<211> 178
<212> PRT
<213> Homo sapien

<400> 2862
 Met Pro Lys Ala Lys Gly Lys Thr Arg Arg Gln Lys Phe Gly Tyr
   1               5                  10                  15

 Ser Val Asn Arg Lys Arg Leu Asn Arg Asn Ala Arg Arg Lys Ala
                  20                  25                  30

 Ala Arg Gly Ile Glu Cys Ser His Ile Arg His Ala Trp Asp His
                  35                  40                  45

 Ala Lys Ser Val Arg Gln Asn Leu Ala Glu Met Gly Leu Ala Val
                  50                  55                  60

 Asp Pro Asn Arg Ala Val Pro Leu Arg Lys Arg Lys Val Lys Ala
                  65                  70                  75

 Met Glu Val Asp Ile Glu Glu Arg Pro Lys Glu Leu Val Arg Lys
                  80                  85                  90

 Pro Tyr Val Leu Asn Asp Leu Glu Ala Glu Ala Ser Leu Pro Glu
                  95                 100                 105

 Lys Lys Gly Asn Thr Leu Ser Arg Asp Leu Ile Asp Tyr Val Arg
                 110                 115                 120

 Tyr Met Val Glu Asn His Gly Glu Asp Tyr Lys Ala Met Ala Arg
                 125                 130                 135

 Asp Glu Lys Asn Tyr Tyr Gln Asp Thr Pro Lys Gln Ile Arg Ser
                 140                 145                 150

 Lys Ile Asn Val Tyr Lys Arg Phe Tyr Pro Ala Glu Trp Gln Asp
                 155                 160                 165

 Phe Leu Asp Ser Leu Gln Lys Arg Lys Met Glu Val Glu
                 170                 175

<210> 2863
<211> 647
<212> DNA
<213> Homo sapien

<400> 2863
 gctcactgag caccgtccca gcatccggac accacagcgg cccttcgctc 50

 cacgcagaaa accacacttc tcataccttc actcaacact tccttcccca 100

 aagccagaag atgcacaagg aggaacatga ggtggctgtg ctgggggcac 150

 cccccagcac catccttcca aggtccaccg tgattaacat ccacagcgag 200

 acctccgtgc ccgaccatgt cgtctggtcc ctgttcaaca ccctcttctt 250

 gaactggtgc tgtctgggct tcatagcatt cgcctactcc gtaaagtcta 300

 gggacaggaa gatggttggc gacgtgaccg gggcccaggc ctatgcctcc 350

 accgccaagt gcctgaacat ctgggccctg attctgggca tcctcatgac 400

 cattggattc atcctgttac tggtattcgg ctctgtaaca gtctaccata 450

 ttatgttaca gataatacag gaaaaacggg gttactagta gccgcccata 500

 gcctgcaacc tttgcactcc actgtgcaat gctggccctg cacgctgggg 550

 ctgttgcccc tgcccccttg gtcctgcccc tagatacagc agtttatacc 600

 cacacacctg tctacagtgt cattcaataa agtgcacgtg cttgtga 647

<210> 2864
<211> 125
<212> PRT
<213> Homo sapien

<400> 2864
 Met His Lys Glu Glu His Glu Val Ala Val Leu Gly Ala Pro Pro
   1               5                  10                  15

 Ser Thr Ile Leu Pro Arg Ser Thr Val Ile Asn Ile His Ser Glu
                  20                  25                  30

 Thr Ser Val Pro Asp His Val Val Trp Ser Leu Phe Asn Thr Leu
                  35                  40                  45

 Phe Leu Asn Trp Cys Cys Leu Gly Phe Ile Ala Phe Ala Tyr Ser
                  50                  55                  60

 Val Lys Ser Arg Asp Arg Lys Met Val Gly Asp Val Thr Gly Ala
                  65                  70                  75

 Gln Ala Tyr Ala Ser Thr Ala Lys Cys Leu Asn Ile Trp Ala Leu
                  80                  85                  90

 Ile Leu Gly Ile Leu Met Thr Ile Gly Phe Ile Leu Leu Leu Val
                  95                 100                 105

 Phe Gly Ser Val Thr Val Tyr His Ile Met Leu Gln Ile Ile Gln
                 110                 115                 120

 Glu Lys Arg Gly Tyr
                 125

<210> 2865
<211> 1274
<212> DNA
<213> Homo sapien

<400> 2865
 ggcacgaggc ccagagaggc tcagctgcac tcgcccggct gggagagctg 50

 ggtgtgggga acatggccgg gcctccgagg ctcctgctgc tgcccctgct 100

 tctggcgctg gctcgcggcc tgcctggggc cctggctgcc caagaggtgc 150

 agcagtctcc ccactgcacg actgtccccg tgggagcctc cgtcaacatc 200

 acctgctcca ccagcggggg cctgcgtggg atctacctga ggcagctcgg 250

 gccacagccc caagacatca tttactacga ggacggggtg gtgcccacta 300

 cggacagacg gttccggggc cgcatcgact tctcagggtc ccaggacaac 350

 ctgactatca ccatgcaccg cctgcagctg tcggacactg gcacctacac 400

 ctgccaggcc atcacggagg tcaatgtcta cggctccggc accctggtcc 450

 tggtgacaga ggaacagtcc caaggatggc acagatgctc ggacgcccca 500

 ccaagggcct ctgccctccc tgccccaccg acaggctccg ccctccctga 550

 cccgcagaca gcctctgccc tccctgaccc gccagcagcc tctgccctcc 600

 ctgcggccct ggcggtgatc tccttcctcc tcgggctggg cctgggggtg 650

 gcgtgtgtgc tggcgaggac acagataaag aaactgtgct cgtggcggga 700

 taagaattcg gcggcatgtg tggtgtacga ggacatgtcg cacagccgct 750

 gcaacacgct gtcctccccc aaccagtacc agtgacccag tgggcccctg 800

 cacgtcccgc ctgtggtccc cccagcacct tccctgcccc accatgcccc 850

 ccaccctgcc acacccctca ccctgctgtc ctcccacggc tgcagcagag 900

 tttgaagggc ccagccgtgc ccagctccaa gcagacacac aggcagtggc 950

 caggccccac ggtgcttctc agtggacaat gatgcctcct ccgggaagcc 1000

 ttccctgccc agcccacgcc gccaccggga ggaagcctga ctgtcctttg 1050

 gctgcatctc ccgaccatgg ccaaggaggg cttttctgtg ggatgggcct 1100

 gggcacgcgg ccctctcctg tcagtgccgg cccacccacc agcaggcccc 1150

 caacccccag gcagcccggc agaggacggg aggagaccag tcccccaccc 1200

 agccgtacca gaaataaagg cttctgtgct tcctttaaaa aaaaaaaaaa 1250

 aaaaaaataa aaaaaaaaaa aaaa 1274

<210> 2866
<211> 240
<212> PRT
<213> Homo sapien

<400> 2866
 Met Ala Gly Pro Pro Arg Leu Leu Leu Leu Pro Leu Leu Leu Ala
   1               5                  10                  15

 Leu Ala Arg Gly Leu Pro Gly Ala Leu Ala Ala Gln Glu Val Gln
                  20                  25                  30

 Gln Ser Pro His Cys Thr Thr Val Pro Val Gly Ala Ser Val Asn
                  35                  40                  45

 Ile Thr Cys Ser Thr Ser Gly Gly Leu Arg Gly Ile Tyr Leu Arg
                  50                  55                  60

 Gln Leu Gly Pro Gln Pro Gln Asp Ile Ile Tyr Tyr Glu Asp Gly
                  65                  70                  75

 Val Val Pro Thr Thr Asp Arg Arg Phe Arg Gly Arg Ile Asp Phe
                  80                  85                  90

 Ser Gly Ser Gln Asp Asn Leu Thr Ile Thr Met His Arg Leu Gln
                  95                 100                 105

 Leu Ser Asp Thr Gly Thr Tyr Thr Cys Gln Ala Ile Thr Glu Val
                 110                 115                 120

 Asn Val Tyr Gly Ser Gly Thr Leu Val Leu Val Thr Glu Glu Gln
                 125                 130                 135

 Ser Gln Gly Trp His Arg Cys Ser Asp Ala Pro Pro Arg Ala Ser
                 140                 145                 150

 Ala Leu Pro Ala Pro Pro Thr Gly Ser Ala Leu Pro Asp Pro Gln
                 155                 160                 165

 Thr Ala Ser Ala Leu Pro Asp Pro Pro Ala Ala Ser Ala Leu Pro
                 170                 175                 180

 Ala Ala Leu Ala Val Ile Ser Phe Leu Leu Gly Leu Gly Leu Gly
                 185                 190                 195

 Val Ala Cys Val Leu Ala Arg Thr Gln Ile Lys Lys Leu Cys Ser
                 200                 205                 210

 Trp Arg Asp Lys Asn Ser Ala Ala Cys Val Val Tyr Glu Asp Met
                 215                 220                 225

 Ser His Ser Arg Cys Asn Thr Leu Ser Ser Pro Asn Gln Tyr Gln
                 230                 235                 240

<210> 2867
<211> 2122
<212> DNA
<213> Homo sapien

<400> 2867
 ggcacgaggc cgagttgcga tgctgtactt ctctttgttt tgggcggctc 50

 ggcctctgca gagatgtggg cagctggtca ggatggccat tcgggctcag 100

 cacagcaacg cagcccagac tcagactggg gaagcaaaca ggggctggac 150

 aggccaggag agcctgtcgg acagtgatcc tgagatgtgg gagttgctgc 200

 agagggagaa ggacaggcag tgtcgtggcc tggagctcat tgcctcagag 250

 aacttctgca gccgagctgc gctggaggcc ctggggtcct gtctgaacaa 300

 caagtactcg gagggttatc ctggcaagag atactatggg ggagcagagg 350

 tggtggatga aattgagctg ctgtgccagc gccgggcctt ggaagccttt 400

 gacctggatc ctgcacagtg gggagtcaat gtccagccct actccgggtc 450

 cccagccaac ctggccgtct acacagccct tctgcaacct cacgaccgga 500

 tcatggggct ggacctgccc gatgggggcc atctcaccca cggctacatg 550

 tctgacgtca agcggatatc agccacgtcc atcttcttcg agtctatgcc 600

 ctataagctc aaccccaaaa ctggcctcat tgactacaac cagctggcac 650

 tgactgctcg acttttccgg ccacggctca tcatagctgg caccagcgcc 700

 tatgctcgcc tcattgacta cgcccgcatg agagaggtgt gtgatgaagt 750

 caaagcacac ctgctggcag acatggccca catcagtggc ctggtggctg 800

 ccaaggtgat tccctcgcct ttcaagcacg cggacatcgt caccaccact 850

 actcacaaga ctcttcgagg ggccaggtca gggctcatct tctaccggaa 900

 aggggtgaag gctgtggacc ccaagactgg ccgggagatc ccttacacat 950

 ttgaggaccg aatcaacttt gccgtgttcc catccctgca ggggggcccc 1000

 cacaatcatg ccattgctgc agtagctgtg gccctaaagc aggcctgcac 1050

 ccccatgttc cgggagtact ccctgcaggt tctgaagaat gctcgggcca 1100

 tggcagatgc cctgctagag cgaggctact cactggtatc aggtggtact 1150

 gacaaccacc tggtgctggt ggacctgcgg cccaagggcc tggatggagc 1200

 tcgggctgag cgggtgctag agcttgtatc catcactgcc aacaagaaca 1250

 cctgtcctgg agaccgaagt gccatcacac cgggcggcct gcggcttggg 1300

 gccccagcct taacttctcg acagttccgt gaggatgact tccggagagt 1350

 tgtggacttt atagatgaag gggtcaacat tggcttagag gtgaagagca 1400

 agactgccaa gctccaggat ttcaaatcct tcctgcttaa ggactcagaa 1450

 acaagtcagc gtctggccaa cctcaggcaa cgggtggagc agtttgccag 1500

 ggccttcccc atgcctggtt ttgatgagca ttgaaggcac ctgggaaatg 1550

 aggcccacag actcaaagtt actctccttc cccctacctg ggccagtgaa 1600

 atagaaagcc tttctatttt ttggtgcggg agggaagacc tctcacttag 1650

 ggcaagagcc aggtatagtc tcccttccca gaatttgtaa ctgagaagat 1700

 cttttctttt tccttttttt ggtaacaaga cttagaagga gggcccaggc 1750

 actttctgtt tgaacccctg tcatgatcac agtgtcagag acgcgtcctc 1800

 tttcttgggg aagttgagga gtgcccttca gagccagtag caggcagggg 1850

 tgggtaggca ccctccttcc tgtttttatc taataaaatg ctaacctgcc 1900

 ctgagtttcc attactgtgg gtggggttcc cctgggccaa acagtgattt 1950

 gtctccctca atgtgtacac cgctccgctc ccaccaccgc taccacaagg 2000

 acccccgggg ctgcagcctc ctctttctgt ctctgatcag agccgacacc 2050

 agacgtgatt agcaggcgca gcaaattcaa tttgttaaat gaaattgtat 2100

 tttgaaaaaa aaaaaaaaaa aa 2122

<210> 2868
<211> 504
<212> PRT
<213> Homo sapien

<400> 2868
 Met Leu Tyr Phe Ser Leu Phe Trp Ala Ala Arg Pro Leu Gln Arg
   1               5                  10                  15

 Cys Gly Gln Leu Val Arg Met Ala Ile Arg Ala Gln His Ser Asn
                  20                  25                  30

 Ala Ala Gln Thr Gln Thr Gly Glu Ala Asn Arg Gly Trp Thr Gly
                  35                  40                  45

 Gln Glu Ser Leu Ser Asp Ser Asp Pro Glu Met Trp Glu Leu Leu
                  50                  55                  60

 Gln Arg Glu Lys Asp Arg Gln Cys Arg Gly Leu Glu Leu Ile Ala
                  65                  70                  75

 Ser Glu Asn Phe Cys Ser Arg Ala Ala Leu Glu Ala Leu Gly Ser
                  80                  85                  90

 Cys Leu Asn Asn Lys Tyr Ser Glu Gly Tyr Pro Gly Lys Arg Tyr
                  95                 100                 105

 Tyr Gly Gly Ala Glu Val Val Asp Glu Ile Glu Leu Leu Cys Gln
                 110                 115                 120

 Arg Arg Ala Leu Glu Ala Phe Asp Leu Asp Pro Ala Gln Trp Gly
                 125                 130                 135

 Val Asn Val Gln Pro Tyr Ser Gly Ser Pro Ala Asn Leu Ala Val
                 140                 145                 150

 Tyr Thr Ala Leu Leu Gln Pro His Asp Arg Ile Met Gly Leu Asp
                 155                 160                 165

 Leu Pro Asp Gly Gly His Leu Thr His Gly Tyr Met Ser Asp Val
                 170                 175                 180

 Lys Arg Ile Ser Ala Thr Ser Ile Phe Phe Glu Ser Met Pro Tyr
                 185                 190                 195

 Lys Leu Asn Pro Lys Thr Gly Leu Ile Asp Tyr Asn Gln Leu Ala
                 200                 205                 210

 Leu Thr Ala Arg Leu Phe Arg Pro Arg Leu Ile Ile Ala Gly Thr
                 215                 220                 225

 Ser Ala Tyr Ala Arg Leu Ile Asp Tyr Ala Arg Met Arg Glu Val
                 230                 235                 240

 Cys Asp Glu Val Lys Ala His Leu Leu Ala Asp Met Ala His Ile
                 245                 250                 255

 Ser Gly Leu Val Ala Ala Lys Val Ile Pro Ser Pro Phe Lys His
                 260                 265                 270

 Ala Asp Ile Val Thr Thr Thr Thr His Lys Thr Leu Arg Gly Ala
                 275                 280                 285

 Arg Ser Gly Leu Ile Phe Tyr Arg Lys Gly Val Lys Ala Val Asp
                 290                 295                 300

 Pro Lys Thr Gly Arg Glu Ile Pro Tyr Thr Phe Glu Asp Arg Ile
                 305                 310                 315

 Asn Phe Ala Val Phe Pro Ser Leu Gln Gly Gly Pro His Asn His
                 320                 325                 330

 Ala Ile Ala Ala Val Ala Val Ala Leu Lys Gln Ala Cys Thr Pro
                 335                 340                 345

 Met Phe Arg Glu Tyr Ser Leu Gln Val Leu Lys Asn Ala Arg Ala
                 350                 355                 360

 Met Ala Asp Ala Leu Leu Glu Arg Gly Tyr Ser Leu Val Ser Gly
                 365                 370                 375

 Gly Thr Asp Asn His Leu Val Leu Val Asp Leu Arg Pro Lys Gly
                 380                 385                 390

 Leu Asp Gly Ala Arg Ala Glu Arg Val Leu Glu Leu Val Ser Ile
                 395                 400                 405

 Thr Ala Asn Lys Asn Thr Cys Pro Gly Asp Arg Ser Ala Ile Thr
                 410                 415                 420

 Pro Gly Gly Leu Arg Leu Gly Ala Pro Ala Leu Thr Ser Arg Gln
                 425                 430                 435

 Phe Arg Glu Asp Asp Phe Arg Arg Val Val Asp Phe Ile Asp Glu
                 440                 445                 450

 Gly Val Asn Ile Gly Leu Glu Val Lys Ser Lys Thr Ala Lys Leu
                 455                 460                 465

 Gln Asp Phe Lys Ser Phe Leu Leu Lys Asp Ser Glu Thr Ser Gln
                 470                 475                 480

 Arg Leu Ala Asn Leu Arg Gln Arg Val Glu Gln Phe Ala Arg Ala
                 485                 490                 495

 Phe Pro Met Pro Gly Phe Asp Glu His
                 500

<210> 2869
<211> 2122
<212> DNA
<213> Homo sapien

<400> 2869
 ggcacgaggc cgagttgcga tgctgtactt ctctttgttt tgggcggctc 50

 ggcctctgca gagatgtggg cagctggtca ggatggccat tcgggctcag 100

 cacagcaacg cagcccagac tcagactggg gaagcaaaca ggggctggac 150

 aggccaggag agcctgtcgg acagtgatcc tgagatgtgg gagttgctgc 200

 agagggagaa ggacaggcag tgtcgtggcc tggagctcat tgcctcagag 250

 aacttctgca gccgagctgc gctggaggcc ctggggtcct gtctgaacaa 300

 caagtactcg gagggttatc ctggcaagag atactatggg ggagcagagg 350

 tggtggatga aattgagctg ctgtgccagc gccgggcctt ggaagccttt 400

 gacctggatc ctgcacagtg gggagtcaat gtccagccct actccgggtc 450

 cccagccaac ctggccgtct acacagccct tctgcaacct cacgaccgga 500

 tcatggggct ggacctgccc gatgggggcc atctcaccca cggctacatg 550

 tctgacgtca agcggatatc agccacgtcc atcttcttcg agtctatgcc 600

 ctataagctc aaccccaaaa ctggcctcat tgactacaac cagctggcac 650

 tgactgctcg acttttccgg ccacggctca tcatagctgg caccagcgcc 700

 tatgctcgcc tcattgacta cgcccgcatg agagaggtgt gtgatgaagt 750

 caaagcacac ctgctggcag acatggccca catcagtggc ctggtggctg 800

 ccaaggtgat tccctcgcct ttcaagcacg cggacatcgt caccaccact 850

 actcacaaga ctcttcgagg ggccaggtca gggctcatct tctaccggaa 900

 aggggtgaag gctgtggacc ccaagactgg ccgggagatc ccttacacat 950

 ttgaggaccg aatcaacttt gccgtgttcc catccctgca ggggggcccc 1000

 cacaatcatg ccattgctgc agtagctgtg gccctaaagc aggcctgcac 1050

 ccccatgttc cgggagtact ccctgcaggt tctgaagaat gctcgggcca 1100

 tggcagatgc cctgctagag cgaggctact cactggtatc aggtggtact 1150

 gacaaccacc tggtgctggt ggacctgcgg cccaagggcc tggatggagc 1200

 tcgggctgag cgggtgctag agcttgtatc catcactgcc aacaagaaca 1250

 cctgtcctgg agaccgaagt gccatcacac cgggcggcct gcggcttggg 1300

 gccccagcct taacttctcg acagttccgt gaggatgact tccggagagt 1350

 tgtggacttt atagatgaag gggtcaacat tggcttagag gtgaagagca 1400

 agactgccaa gctccaggat ttcaaatcct tcctgcttaa ggactcagaa 1450

 acaagtcagc gtctggccaa cctcaggcaa cgggtggagc agtttgccag 1500

 ggccttcccc atgcctggtt ttgatgagca ttgaaggcac ctgggaaatg 1550

 aggcccacag actcaaagtt actctccttc cccctacctg ggccagtgaa 1600

 atagaaagcc tttctatttt ttggtgcggg agggaagacc tctcacttag 1650

 ggcaagagcc aggtatagtc tcccttccca gaatttgtaa ctgagaagat 1700

 cttttctttt tccttttttt ggtaacaaga cttagaagga gggcccaggc 1750

 actttctgtt tgaacccctg tcatgatcac agtgtcagag acgcgtcctc 1800

 tttcttgggg aagttgagga gtgcccttca gagccagtag caggcagggg 1850

 tgggtaggca ccctccttcc tgtttttatc taataaaatg ctaacctgcc 1900

 ctgagtttcc attactgtgg gtggggttcc cctgggccaa acagtgattt 1950

 gtctccctca atgtgtacac cgctccgctc ccaccaccgc taccacaagg 2000

 acccccgggg ctgcagcctc ctctttctgt ctctgatcag agccgacacc 2050

 agacgtgatt agcaggcgca gcaaattcaa tttgttaaat gaaattgtat 2100

 tttgaaaaaa aaaaaaaaaa aa 2122

<210> 2870
<211> 504
<212> PRT
<213> Homo sapien

<400> 2870
 Met Leu Tyr Phe Ser Leu Phe Trp Ala Ala Arg Pro Leu Gln Arg
   1               5                  10                  15

 Cys Gly Gln Leu Val Arg Met Ala Ile Arg Ala Gln His Ser Asn
                  20                  25                  30

 Ala Ala Gln Thr Gln Thr Gly Glu Ala Asn Arg Gly Trp Thr Gly
                  35                  40                  45

 Gln Glu Ser Leu Ser Asp Ser Asp Pro Glu Met Trp Glu Leu Leu
                  50                  55                  60

 Gln Arg Glu Lys Asp Arg Gln Cys Arg Gly Leu Glu Leu Ile Ala
                  65                  70                  75

 Ser Glu Asn Phe Cys Ser Arg Ala Ala Leu Glu Ala Leu Gly Ser
                  80                  85                  90

 Cys Leu Asn Asn Lys Tyr Ser Glu Gly Tyr Pro Gly Lys Arg Tyr
                  95                 100                 105

 Tyr Gly Gly Ala Glu Val Val Asp Glu Ile Glu Leu Leu Cys Gln
                 110                 115                 120

 Arg Arg Ala Leu Glu Ala Phe Asp Leu Asp Pro Ala Gln Trp Gly
                 125                 130                 135

 Val Asn Val Gln Pro Tyr Ser Gly Ser Pro Ala Asn Leu Ala Val
                 140                 145                 150

 Tyr Thr Ala Leu Leu Gln Pro His Asp Arg Ile Met Gly Leu Asp
                 155                 160                 165

 Leu Pro Asp Gly Gly His Leu Thr His Gly Tyr Met Ser Asp Val
                 170                 175                 180

 Lys Arg Ile Ser Ala Thr Ser Ile Phe Phe Glu Ser Met Pro Tyr
                 185                 190                 195

 Lys Leu Asn Pro Lys Thr Gly Leu Ile Asp Tyr Asn Gln Leu Ala
                 200                 205                 210

 Leu Thr Ala Arg Leu Phe Arg Pro Arg Leu Ile Ile Ala Gly Thr
                 215                 220                 225

 Ser Ala Tyr Ala Arg Leu Ile Asp Tyr Ala Arg Met Arg Glu Val
                 230                 235                 240

 Cys Asp Glu Val Lys Ala His Leu Leu Ala Asp Met Ala His Ile
                 245                 250                 255

 Ser Gly Leu Val Ala Ala Lys Val Ile Pro Ser Pro Phe Lys His
                 260                 265                 270

 Ala Asp Ile Val Thr Thr Thr Thr His Lys Thr Leu Arg Gly Ala
                 275                 280                 285

 Arg Ser Gly Leu Ile Phe Tyr Arg Lys Gly Val Lys Ala Val Asp
                 290                 295                 300

 Pro Lys Thr Gly Arg Glu Ile Pro Tyr Thr Phe Glu Asp Arg Ile
                 305                 310                 315

 Asn Phe Ala Val Phe Pro Ser Leu Gln Gly Gly Pro His Asn His
                 320                 325                 330

 Ala Ile Ala Ala Val Ala Val Ala Leu Lys Gln Ala Cys Thr Pro
                 335                 340                 345

 Met Phe Arg Glu Tyr Ser Leu Gln Val Leu Lys Asn Ala Arg Ala
                 350                 355                 360

 Met Ala Asp Ala Leu Leu Glu Arg Gly Tyr Ser Leu Val Ser Gly
                 365                 370                 375

 Gly Thr Asp Asn His Leu Val Leu Val Asp Leu Arg Pro Lys Gly
                 380                 385                 390

 Leu Asp Gly Ala Arg Ala Glu Arg Val Leu Glu Leu Val Ser Ile
                 395                 400                 405

 Thr Ala Asn Lys Asn Thr Cys Pro Gly Asp Arg Ser Ala Ile Thr
                 410                 415                 420

 Pro Gly Gly Leu Arg Leu Gly Ala Pro Ala Leu Thr Ser Arg Gln
                 425                 430                 435

 Phe Arg Glu Asp Asp Phe Arg Arg Val Val Asp Phe Ile Asp Glu
                 440                 445                 450

 Gly Val Asn Ile Gly Leu Glu Val Lys Ser Lys Thr Ala Lys Leu
                 455                 460                 465

 Gln Asp Phe Lys Ser Phe Leu Leu Lys Asp Ser Glu Thr Ser Gln
                 470                 475                 480

 Arg Leu Ala Asn Leu Arg Gln Arg Val Glu Gln Phe Ala Arg Ala
                 485                 490                 495

 Phe Pro Met Pro Gly Phe Asp Glu His
                 500

<210> 2871
<211> 1067
<212> DNA
<213> Homo sapien

<400> 2871
 atgacctttc ctctttatct tccttgttgt gcaggtaaag aaaccaagtg 50

 gaagagtgtt tcctcctctg gccgtaaagc agctgtcccc gccctactcc 100

 ggaccgcccc aaagactcca tgggatggac ctgagtcagc cgaatcctag 150

 ccccttccct tgggcctgct gtggtgctcg acatcagtga cagacggaag 200

 cagcagacca tcaaggctac gggaggcccg gggcgcttgc gaagatgaag 250

 tttggctgcc tctccttccg gcagccttat gctggctttg tcttaaatgg 300

 aatcaagact gtggagacgc gctggcgtcc tctgctgagc agccagcgga 350

 actgtaccat cgccgtccac attgctcaca gggactggga aggcgatgcc 400

 tgtcgggagc tgctggtgga gagactcggg atgactcctg ctcagattca 450

 ggccttgctc aggaaagggg aaaagtttgg tcgaggagtg atagcgggac 500

 tcgttgacat tggggaaact ttgcaatgcc ccgaagactt aactcccgat 550

 gaggttgtgg aactagaaaa tcaagctgca ctgaccaacc tgaagcagaa 600

 gtacctgact gtgatttcaa accccaggtg gttactggag cccataccta 650

 ggaaaggagg caaggatgta ttccaggtag acatcccaga gcacctgatc 700

 cctttggggc atgaagtgtg acaagtgtgg gctcctgaaa ggaatgttcc 750

 agagaaacca gctaaatcat ggcaccttca atttgccatc gtgacgcaga 800

 cctgtataaa ttaggttaaa gatgaatttc cactgctttg gagagtccca 850

 cccactaagc actgtgcatg taaacaggtt cctttgctca gatgaaggaa 900

 gtagggggtg gggctttcct tgtgtgatgc ctccttaggc acacaggcaa 950

 tgtctcaagt actttgacct tagggtagaa ggcaaagctg ccagtaaatg 1000

 tctcagcatt gctgctaatt ttggtcctgc tagtttctgg attgtacaaa 1050

 taaatgtgtt gtagatg 1067

<210> 2872
<211> 2787
<212> DNA
<213> Homo sapien

<400> 2872
 gcacagacga gatctcgatc gaaggcgaga tggcggacgt gctagatctt 50

 cacgaggctg ggggcgaaga tttcgccatg gatgaggatg gggacgagag 100

 cattcacaaa ctgaaagaaa aagcgaagaa acggaagggt cgcggctttg 150

 gctccgaaga ggggtcccga gcgcggatgc gtgaggatta tgacagcgtg 200

 gagcaggatg gcgatgaacc cggaccacaa cgctctgttg aaggctggat 250

 tctctttgta actggagtcc atgaggaagc caccgaagaa gacatacacg 300

 acaaattcgc agaatatggg gaaattaaaa acattcatct caacctcgac 350

 aggcgaacag gatatctgaa ggggtatact ctagttgaat atgaaacata 400

 caaggaagcc caggctgcta tggagggact caatggccag gatttgatgg 450

 gacagcccat cagcgttgac tggtgttttg ttcggggtcc accaaaaggc 500

 aagaggagag gtggccgaag acgcagcaga agtccagacc ggagacgtcg 550

 ctgacaggtc ctctgttgtc caggtgttct cttcaagatt ccatttgacc 600

 atgcagcctt ggacaaatag gactggggtg gaacttgctg tgtttatatt 650

 taatctctta ccgtatatgc gtagtatttg agttgcgaat aaatgttcca 700

 tttttgtttt ctacatttaa tgttactttc ctgtcctaaa attgaaagtt 750

 ctaaagcata gcaaggctgt atggatcatt gtgaagatac ttctagggac 800

 tgaactctat gtatttcttt tttttctttt ttttgagata gagtcttgct 850

 gtgttaccca gggtggattg cagctgatca tagctcactg cagcttcaaa 900

 ctcttgggct caagccatcc ttctgcctca ctgtccctag tagttgggat 950

 tacaggcaca tgccaccatg cccagctaaa tttttaatat ttttgtagag 1000

 atggggtctt gctgtgttac ctgggctagt tatgtgagtt tctatattag 1050

 acatagtctc aagtttcagg tagggtttaa agtagagaca ctggtcagta 1100

 tttctttttt ggggggaact aggagagcag gagtagaagt gagatgttaa 1150

 gatcttatgg cactaaagac ttactattct gttcctacat actctgttag 1200

 gatcagatag atgttataga aatgcctttt gtttctcctg cccttcttga 1250

 tgtcacagtt ttttgtactt ccagctgtct aaaggcatga atctcctctt 1300

 ggagcattct cccagaccct tctttagaag agtctatact aagttcttgg 1350

 tgccctcttc ggcagccaag ggtgaaggcc ccatagagga gaggatccaa 1400

 aggagcattg aggaggccca agaggaaaag gatgtggctc aggctgggag 1450

 ggacttcagt tagcatggtg ggggagaacc agtaccacat acccagtagg 1500

 taataaggtg tccagcagag gatgaaggtc agcaagataa gcagggccag 1550

 tctcagggcc cggagacgaa cacggggaca attgtcaaag gagcggggga 1600

 gggcaaattc accagcaggg gctaggaatt tagaaaatat actgtaattc 1650

 agacactcag cttctgatct gagtataggg tgaattgatg gaggggcata 1700

 gctagtgaga cagagctcgc ctcctacaag gaggagaatg ttgcaaaccg 1750

 ttttcccctt cccaacctgg gactatatga tttcttaccc ccagggatta 1800

 tgatagaaat atgaagccac caagtctaga cttgatggtg ttcaagaata 1850

 aataatactg attgcctccc tagtccttgt ccagctaact cagctgttta 1900

 taattgaagg gattcaacaa aattatctct agcatcaggt gctagacatg 1950

 gttagaatct caccatggtt tagtgactgg tagatagcta ttaggtaggt 2000

 agataaataa atgatgctag aggcaacagg tctagggtta aggattaagg 2050

 cctgggaatt ggagtctcac catggctccc cttccttgtc tggggcctgg 2100

 acacactgag gacaatgcgg ctatagcaga tggccatggc agtcagtggc 2150

 agcagaaaga ggcagcagaa ggtgaagagg ttataggtgg tctcttgcca 2200

 ttgagccttg aagctgcctt tggtgacaca ctgagtgaaa gggactgggc 2250

 cagctcagtg gaccgtgtgg aacaggaaca gctggagtgg agttgaggac 2300

 tattagaact ggttcccctc accacccaac ctacccacct atgtcatact 2350

 gtctcctccc aattcatcct taattccaag tgaagcagca cagtgctgag 2400

 aaacagttca tccatggtgc catgttaaag aagttggaaa tatatcttga 2450

 aaatcctatc ttccttttag gcttgaatat gatgctgaac agtaagtttg 2500

 ttaaatcttg gaacttaaaa caatcctgct ttctcaagta ctattctaac 2550

 attgcgcttt ataagggatg atatttctac cacctcactc atatttttag 2600

 ctgaaatgat tttcctggta tgtctgttat tttgtggaaa aagaaatatt 2650

 gtgtaaaatg ggtgctgcca aaattccagg ccattttgca gggactctga 2700

 agtgaccttt agtagtaata gtcttatgtg cagtaactat aatggtaaag 2750

 aatgttaaat aataaaattt aacattttcc aaatgct 2787

<210> 2873
<211> 174
<212> PRT
<213> Homo sapien

<400> 2873
 Met Ala Asp Val Leu Asp Leu His Glu Ala Gly Gly Glu Asp Phe
   1               5                  10                  15

 Ala Met Asp Glu Asp Gly Asp Glu Ser Ile His Lys Leu Lys Glu
                  20                  25                  30

 Lys Ala Lys Lys Arg Lys Gly Arg Gly Phe Gly Ser Glu Glu Gly
                  35                  40                  45

 Ser Arg Ala Arg Met Arg Glu Asp Tyr Asp Ser Val Glu Gln Asp
                  50                  55                  60

 Gly Asp Glu Pro Gly Pro Gln Arg Ser Val Glu Gly Trp Ile Leu
                  65                  70                  75

 Phe Val Thr Gly Val His Glu Glu Ala Thr Glu Glu Asp Ile His
                  80                  85                  90

 Asp Lys Phe Ala Glu Tyr Gly Glu Ile Lys Asn Ile His Leu Asn
                  95                 100                 105

 Leu Asp Arg Arg Thr Gly Tyr Leu Lys Gly Tyr Thr Leu Val Glu
                 110                 115                 120

 Tyr Glu Thr Tyr Lys Glu Ala Gln Ala Ala Met Glu Gly Leu Asn
                 125                 130                 135

 Gly Gln Asp Leu Met Gly Gln Pro Ile Ser Val Asp Trp Cys Phe
                 140                 145                 150

 Val Arg Gly Pro Pro Lys Gly Lys Arg Arg Gly Gly Arg Arg Arg
                 155                 160                 165

 Ser Arg Ser Pro Asp Arg Arg Arg Arg
                 170

<210> 2874
<211> 1016
<212> DNA
<213> Homo sapien

<400> 2874
 tcattgactg ccaaagagga tgtcagcata cccagatcca cattaggaga 50

 tttggacaca gttgcagggc tggaaaaaga actgagtaat gccaaagagg 100

 aacttgaact catggctaaa aaagaaagag aaagtcagat ggaactttct 150

 gctctacagt ccatgatggc tgtgcaggaa gaagagctgc aggtgcaggc 200

 tgctgatatg gagtctctga ccaggaacat acagattaaa gaagatctca 250

 taaaggacct gcaaatgcaa ctggttgatc ctgaagacat accagctatg 300

 gaacgcctga cccaggaagt cttacttctt cgggaaaaag ttgcttcagt 350

 agaatcccag ggtcaagaaa tttcaggaaa ccgaagacaa cagttgctgc 400

 tgatgctaga aggactagta gatgaacgga gtcggctcaa tgaggcctta 450

 caagcagaga gacagctcta tagcagtctg gtgaagttcc atgcccatcc 500

 agagagctct gagagagacc gaactctgca ggtggaactg gaaggggctc 550

 aggtgttacg cagtcggcta gaagaagttc ttggaagaag cttggagcgc 600

 ttaaacaggc tggagaccct ggccgccatt ggaggtgggg aactggaaag 650

 tgtgcgaatt catcacaagc atgcctactg agcactggcg ggtcagactg 700

 cagcccagga tggaaaacct tgtttgcact aaccagaaag atccttgtct 750

 gattttggca gaattaaacg gtgacttact aatgatagaa ctggtacaag 800

 tagcatcaac tacaaagtga aactcacttt agcctacatg gatctcactg 850

 tacatacata tcaatcccta aattgaatgg tggaggttgc aaagtgtatt 900

 tgcacatttt aaatcattct gttttagttt ttccactttt attcattctt 950

 atccctagcc ccttctcgtt ccctcatccc ttctgtgggc caataaagtt 1000

 tattcttccc caaaaa 1016

<210> 2875
<211> 226
<212> PRT
<213> Homo sapien

<400> 2875
 Ser Leu Thr Ala Lys Glu Asp Val Ser Ile Pro Arg Ser Thr Leu
   1               5                  10                  15

 Gly Asp Leu Asp Thr Val Ala Gly Leu Glu Lys Glu Leu Ser Asn
                  20                  25                  30

 Ala Lys Glu Glu Leu Glu Leu Met Ala Lys Lys Glu Arg Glu Ser
                  35                  40                  45

 Gln Met Glu Leu Ser Ala Leu Gln Ser Met Met Ala Val Gln Glu
                  50                  55                  60

 Glu Glu Leu Gln Val Gln Ala Ala Asp Met Glu Ser Leu Thr Arg
                  65                  70                  75

 Asn Ile Gln Ile Lys Glu Asp Leu Ile Lys Asp Leu Gln Met Gln
                  80                  85                  90

 Leu Val Asp Pro Glu Asp Ile Pro Ala Met Glu Arg Leu Thr Gln
                  95                 100                 105

 Glu Val Leu Leu Leu Arg Glu Lys Val Ala Ser Val Glu Ser Gln
                 110                 115                 120

 Gly Gln Glu Ile Ser Gly Asn Arg Arg Gln Gln Leu Leu Leu Met
                 125                 130                 135

 Leu Glu Gly Leu Val Asp Glu Arg Ser Arg Leu Asn Glu Ala Leu
                 140                 145                 150

 Gln Ala Glu Arg Gln Leu Tyr Ser Ser Leu Val Lys Phe His Ala
                 155                 160                 165

 His Pro Glu Ser Ser Glu Arg Asp Arg Thr Leu Gln Val Glu Leu
                 170                 175                 180

 Glu Gly Ala Gln Val Leu Arg Ser Arg Leu Glu Glu Val Leu Gly
                 185                 190                 195

 Arg Ser Leu Glu Arg Leu Asn Arg Leu Glu Thr Leu Ala Ala Ile
                 200                 205                 210

 Gly Gly Gly Glu Leu Glu Ser Val Arg Ile His His Lys His Ala
                 215                 220                 225

 Tyr


<210> 2876
<211> 467
<212> DNA
<213> Homo sapien

<400> 2876
 ccagcctggg caacacggtg agaccctgtc cctacaaaaa atgagagttg 50

 cagtttttag ctccagttgc tatttttcat caaatcaagg ctggtattta 100

 gctgatatgt accacaacta ttatatgtag ctggccttat gtgttgttat 150

 atatttagaa tattactctt gcatcaagct gtttcttttg ctaactgctt 200

 gttaacagtt aactagcact gctaaaagca tttatattga tttttttccc 250

 atacaggcac atgatggctc cgctacttac ttgagattca ttattgtatc 300

 agcctttgat cattttgcat ctgtgcatag cgtttctgca gaaggaacag 350

 tagtctcaaa tctttcctca taatgataac aaaatgctct tgcatgattt 400

 tttaacaata tatttaaaca ggaagttgtc actgatatac tttattaaaa 450

 ggatttttat caaaaaa 467

<210> 2877
<211> 42
<212> PRT
<213> Homo sapien

<400> 2877
 Gln Pro Gly Gln His Gly Glu Thr Leu Ser Leu Gln Lys Met Arg
   1               5                  10                  15

 Val Ala Val Phe Ser Ser Ser Cys Tyr Phe Ser Ser Asn Gln Gly
                  20                  25                  30

 Trp Tyr Leu Ala Asp Met Tyr His Asn Tyr Tyr Met
                  35                  40

<210> 2878
<211> 590
<212> DNA
<213> Homo sapien

<400> 2878
 cctgaggcgg cggcgcgagg cagtttcttt tctgattctg agatgcttgt 50

 gagagcttca gccatctagg aacgcatacg ctgctgcttg accacgctgt 100

 agcagtatgg tttgaagtgg tgaacatgga tttttctcgg cttcacatgt 150

 acagtcctcc ccagtgtgtg ccggagaaca cgggctacac gtatgcgctc 200

 agttccagct attcttcaga tgctctggat tttgagacgg agcacaaatt 250

 ggaccctgta tttgattctc cacggatgtc ccgccgtagt ttgcgcctgg 300

 ccacgacagc atgcaccctg ggggatggtg aggctgtggg tgccgacagc 350

 ggcaccagca gcgctgtctc cctgaagaac cgagcggcca ggtgagcacc 400

 gctgcacttc ctctccatct gatctctaac accagttaaa accaagcttc 450

 catacttttt ggtctgtaaa gccgcaccct gtctcgagct taaggatatg 500

 tgtgtgtatg tgcgtgtaca gacacacaaa cctgtcatat aaagtggtag 550

 tttgctgcaa ataaagactg aaaggaactc tggaaaaaaa 590

<210> 2879
<211> 89
<212> PRT
<213> Homo sapien

<400> 2879
 Met Asp Phe Ser Arg Leu His Met Tyr Ser Pro Pro Gln Cys Val
   1               5                  10                  15

 Pro Glu Asn Thr Gly Tyr Thr Tyr Ala Leu Ser Ser Ser Tyr Ser
                  20                  25                  30

 Ser Asp Ala Leu Asp Phe Glu Thr Glu His Lys Leu Asp Pro Val
                  35                  40                  45

 Phe Asp Ser Pro Arg Met Ser Arg Arg Ser Leu Arg Leu Ala Thr
                  50                  55                  60

 Thr Ala Cys Thr Leu Gly Asp Gly Glu Ala Val Gly Ala Asp Ser
                  65                  70                  75

 Gly Thr Ser Ser Ala Val Ser Leu Lys Asn Arg Ala Ala Arg
                  80                  85

<210> 2880
<211> 3213
<212> DNA
<213> Homo sapien

<400> 2880
 gaccgaagca agagctggtt caggtggcag ccacagcagc ctcagggacc 50

 tcagcaacta tggcctcctg cccagactct gataatagct gggtgcttgc 100

 tggctccgag agcctgccag tggagacact gggcccggca tccaggatgg 150

 acccagaatc tgagagagcc ctgcaggccc ctcacagccc ctccaagaca 200

 gatgggaaag aattagctgg gaccatggat ggagaaggga cgctcttcca 250

 gactgaaagc cctcagtctg gcagcattct aacagaggag actgaggtca 300

 agggcaccct ggaaggtgat gtttgtggtg tggagcctcc tggcccagga 350

 gacacagtag tccagggaga cctgcaggag accaccgtgg tgacaggcct 400

 gggaccagac acacaggacc tggaaggcca gagccctcca cagagcctgc 450

 cttcaacccc caaagcagct tggatcaggg aggagggccg ctgctccagc 500

 agtgacgatg acaccgacgt ggacatggag ggtctgcgga gacggcgggg 550

 ccgggaggcc ggcccacctc agcccatggt gcccctggct gtggagaacc 600

 aggctggggg tgagggtgca ggcggggagc tgggcatctc cctcaacatg 650

 tgcctccttg gggccctggt tctgcttggc ctgggggtcc tcctcttctc 700

 aggtggcctc tcagagtctg agactgggcc catggaggaa gtggagcggc 750

 aggtcctccc agaccccgag gtgctggaag ctgtggggga caggcaggat 800

 gggctaaggg aacagctgca ggccccagtg cctcctgaca gtgtccccag 850

 cctgcaaaac atgggtcttc tgctggacaa gctggccaag gagaaccagg 900

 acatccggct gctgcaggcc cagctgcagg cccaaaagga agagcttcag 950

 agcctgatgc accagcccaa agggctagag gaggagaatg cccagctccg 1000

 gggggctctg cagcagggcg aagccttcca gcgggctctg gagtcagagc 1050

 tgcagcagct gcgggcccgg ctccaggggc tggaggccga ctgtgtccgg 1100

 ggcccagatg gggtgtgcct cagtgggggt agaggcccac agggtgacaa 1150

 ggccatcagg gagcaaggcc ccagggagca ggagccagaa ctcagcttcc 1200

 tgaagcagaa ggaacagctg gaggctgagg cacaggcatt aaggcaagag 1250

 ttagagaggc agcgacggct gctggggtct gtacagcagg atctggagag 1300

 gagcttgcag gatgccagcc gcggggaccc agctcatgct ggcttggctg 1350

 agctgggcca cagattggcc cagaaactgc agggcctgga gaactggggc 1400

 caggaccctg gggtctctgc caatgcctca aaggcctggc accagaagtc 1450

 ccacttccag aattctaggg agtggagtgg aaaggaaaag tggtgggatg 1500

 ggcagagaga ccggaaggct gagcactgga aacataagaa ggaagaatct 1550

 ggccgggaaa ggaagaagaa ctggggaggt caggaggaca gggagccagc 1600

 aggaaggtgg aaggagggca ggccaagggt ggaggagtcg gggagcaaga 1650

 aggagggcaa gcgacagggc ccgaaggaac ccccaaggaa aagtggtagc 1700

 ttccactcct ctggagaaaa gcagaagcaa cctcggtgga gggaagggac 1750

 taaggacagc catgaccccc tgccatcctg ggcagagctg ttgaggccca 1800

 agtaccgggc accccagggc tgctcaggtg tggacgagtg tgcccggcag 1850

 gagggcctga ctttctttgg cacagagcta gccccagtgc ggcaacagga 1900

 gctggcctct ctgctaagaa catacttggc acggctgccc tgggctgggc 1950

 agctgaccaa ggagctaccc ctctcacctg ctttctttgg tgaggatggc 2000

 atcttccgtc atgaccgcct ccgcttccgg gattttgtgg atgccctgga 2050

 ggacagcttg gaggaggtgg ctgtgcaaca gacaggtgat gatgatgaag 2100

 tagatgactt tgaggacttc atcttcagcc acttctttgg agacaaagca 2150

 ctgaagaaga ggtcagggaa gaaggacaag cactcacaga gcccaagagc 2200

 tgcggggccc agggaggggc acagccatag ccaccaccac caccaccggg 2250

 gctgacaccc tgccccacag ggaatggcct tggcctggcc cagcccaaga 2300

 tcccagcgtt atctaactcc tggagggtgg actctgtcct ggcttgtttg 2350

 gtgtcctcag atatctttca cacagtagag caaaatcacc agccctgcac 2400

 tgatgtcact ttatgtagaa aaaggcctta gctggacctg cgttgccgtc 2450

 tatgcaaatg catgcaaata ctccaggccc tgggatgtgg gcttgtgttt 2500

 tgtcactgtg aagggggaga tgggagagga gcctgttttg gggtggggtc 2550

 tggggaaggc aatctgattc tgaagctaaa gagctttcat cctcttgagt 2600

 gtatgtcccc atagtgggcc ccttgaccca catgctgacc ggtgccttgg 2650

 gatttgacta gagttgctgg ctcgaggccc agcacgagga cttaccctgg 2700

 ggttttgtta ggtttggaag cagctgtccc tagggggtga agtccccccc 2750

 cttttttttt ttacccctgc ttctcccacg gcttcacctc cctatgtgaa 2800

 ctgtagactc agatcccaat aaagtgctgt tgcagctatg atgctaggtg 2850

 gtttctaagc acaggggaca ccccacaccc cctgcctgaa tggatgggtc 2900

 catcccaggc actggtactt gcccccttgt tctgtatccc cctttgccct 2950

 tgccttgccc ttccaacaaa ccctaggccc ttgagaagct gatacttctc 3000

 cttttgctca cagctgcctt ggccccaccc ctgggagatg tagcaaattg 3050

 agtgtgggtt ttggagtctg agcctcaggc tcaaatccag gccaagtgat 3100

 cttgggcaag ttaatctctg ggaactttgg gtttcttatc ctcaaaaaag 3150

 gcgatggaag ggctggggaa gtgattaaat aaaagcaacg caagaaaaaa 3200

 aaaaaaaaaa aaa 3213

<210> 2881
<211> 731
<212> PRT
<213> Homo sapien

<400> 2881
 Met Ala Ser Cys Pro Asp Ser Asp Asn Ser Trp Val Leu Ala Gly
   1               5                  10                  15

 Ser Glu Ser Leu Pro Val Glu Thr Leu Gly Pro Ala Ser Arg Met
                  20                  25                  30

 Asp Pro Glu Ser Glu Arg Ala Leu Gln Ala Pro His Ser Pro Ser
                  35                  40                  45

 Lys Thr Asp Gly Lys Glu Leu Ala Gly Thr Met Asp Gly Glu Gly
                  50                  55                  60

 Thr Leu Phe Gln Thr Glu Ser Pro Gln Ser Gly Ser Ile Leu Thr
                  65                  70                  75

 Glu Glu Thr Glu Val Lys Gly Thr Leu Glu Gly Asp Val Cys Gly
                  80                  85                  90

 Val Glu Pro Pro Gly Pro Gly Asp Thr Val Val Gln Gly Asp Leu
                  95                 100                 105

 Gln Glu Thr Thr Val Val Thr Gly Leu Gly Pro Asp Thr Gln Asp
                 110                 115                 120

 Leu Glu Gly Gln Ser Pro Pro Gln Ser Leu Pro Ser Thr Pro Lys
                 125                 130                 135

 Ala Ala Trp Ile Arg Glu Glu Gly Arg Cys Ser Ser Ser Asp Asp
                 140                 145                 150

 Asp Thr Asp Val Asp Met Glu Gly Leu Arg Arg Arg Arg Gly Arg
                 155                 160                 165

 Glu Ala Gly Pro Pro Gln Pro Met Val Pro Leu Ala Val Glu Asn
                 170                 175                 180

 Gln Ala Gly Gly Glu Gly Ala Gly Gly Glu Leu Gly Ile Ser Leu
                 185                 190                 195

 Asn Met Cys Leu Leu Gly Ala Leu Val Leu Leu Gly Leu Gly Val
                 200                 205                 210

 Leu Leu Phe Ser Gly Gly Leu Ser Glu Ser Glu Thr Gly Pro Met
                 215                 220                 225

 Glu Glu Val Glu Arg Gln Val Leu Pro Asp Pro Glu Val Leu Glu
                 230                 235                 240

 Ala Val Gly Asp Arg Gln Asp Gly Leu Arg Glu Gln Leu Gln Ala
                 245                 250                 255

 Pro Val Pro Pro Asp Ser Val Pro Ser Leu Gln Asn Met Gly Leu
                 260                 265                 270

 Leu Leu Asp Lys Leu Ala Lys Glu Asn Gln Asp Ile Arg Leu Leu
                 275                 280                 285

 Gln Ala Gln Leu Gln Ala Gln Lys Glu Glu Leu Gln Ser Leu Met
                 290                 295                 300

 His Gln Pro Lys Gly Leu Glu Glu Glu Asn Ala Gln Leu Arg Gly
                 305                 310                 315

 Ala Leu Gln Gln Gly Glu Ala Phe Gln Arg Ala Leu Glu Ser Glu
                 320                 325                 330

 Leu Gln Gln Leu Arg Ala Arg Leu Gln Gly Leu Glu Ala Asp Cys
                 335                 340                 345

 Val Arg Gly Pro Asp Gly Val Cys Leu Ser Gly Gly Arg Gly Pro
                 350                 355                 360

 Gln Gly Asp Lys Ala Ile Arg Glu Gln Gly Pro Arg Glu Gln Glu
                 365                 370                 375

 Pro Glu Leu Ser Phe Leu Lys Gln Lys Glu Gln Leu Glu Ala Glu
                 380                 385                 390

 Ala Gln Ala Leu Arg Gln Glu Leu Glu Arg Gln Arg Arg Leu Leu
                 395                 400                 405

 Gly Ser Val Gln Gln Asp Leu Glu Arg Ser Leu Gln Asp Ala Ser
                 410                 415                 420

 Arg Gly Asp Pro Ala His Ala Gly Leu Ala Glu Leu Gly His Arg
                 425                 430                 435

 Leu Ala Gln Lys Leu Gln Gly Leu Glu Asn Trp Gly Gln Asp Pro
                 440                 445                 450

 Gly Val Ser Ala Asn Ala Ser Lys Ala Trp His Gln Lys Ser His
                 455                 460                 465

 Phe Gln Asn Ser Arg Glu Trp Ser Gly Lys Glu Lys Trp Trp Asp
                 470                 475                 480

 Gly Gln Arg Asp Arg Lys Ala Glu His Trp Lys His Lys Lys Glu
                 485                 490                 495

 Glu Ser Gly Arg Glu Arg Lys Lys Asn Trp Gly Gly Gln Glu Asp
                 500                 505                 510

 Arg Glu Pro Ala Gly Arg Trp Lys Glu Gly Arg Pro Arg Val Glu
                 515                 520                 525

 Glu Ser Gly Ser Lys Lys Glu Gly Lys Arg Gln Gly Pro Lys Glu
                 530                 535                 540

 Pro Pro Arg Lys Ser Gly Ser Phe His Ser Ser Gly Glu Lys Gln
                 545                 550                 555

 Lys Gln Pro Arg Trp Arg Glu Gly Thr Lys Asp Ser His Asp Pro
                 560                 565                 570

 Leu Pro Ser Trp Ala Glu Leu Leu Arg Pro Lys Tyr Arg Ala Pro
                 575                 580                 585

 Gln Gly Cys Ser Gly Val Asp Glu Cys Ala Arg Gln Glu Gly Leu
                 590                 595                 600

 Thr Phe Phe Gly Thr Glu Leu Ala Pro Val Arg Gln Gln Glu Leu
                 605                 610                 615

 Ala Ser Leu Leu Arg Thr Tyr Leu Ala Arg Leu Pro Trp Ala Gly
                 620                 625                 630

 Gln Leu Thr Lys Glu Leu Pro Leu Ser Pro Ala Phe Phe Gly Glu
                 635                 640                 645

 Asp Gly Ile Phe Arg His Asp Arg Leu Arg Phe Arg Asp Phe Val
                 650                 655                 660

 Asp Ala Leu Glu Asp Ser Leu Glu Glu Val Ala Val Gln Gln Thr
                 665                 670                 675

 Gly Asp Asp Asp Glu Val Asp Asp Phe Glu Asp Phe Ile Phe Ser
                 680                 685                 690

 His Phe Phe Gly Asp Lys Ala Leu Lys Lys Arg Ser Gly Lys Lys
                 695                 700                 705

 Asp Lys His Ser Gln Ser Pro Arg Ala Ala Gly Pro Arg Glu Gly
                 710                 715                 720

 His Ser His Ser His His His His His Arg Gly
                 725                 730

<210> 2882
<211> 4760
<212> DNA
<213> Homo sapien

<400> 2882
 ggccggcggt ggcggcggcg agggctggac tcgggcttag ggcctgctgt 50

 ggaggcagcg gcggacgccg agctaagcag tttctctgga aacccccctg 100

 gtaagtgtgg aggaggcggg acactctgac ccaagacgaa aggcctgtag 150

 ctccagccaa agaaaataaa ccttaggagg gagaaggaaa aaaaaaaatc 200

 catcagctgt tcctgagaac agcctgcatt ggaatctaca gagaggacaa 250

 ctaatgtgag tgaggaagtg actgtatgtg gactgtggag aaagtaagtc 300

 acgtgggccc ttgaggacct ggactgggtt aggaacagtt gtactttcag 350

 aggtgaggtg tcgagaaggg aaagtgaatg tggtctggag tgtgtccttg 400

 gccttggctc cacagggtgt gctttcctct ggggccgtca gggagctcat 450

 cccttgtgtt ctgccagggt ggggtacggg gtttgacact gaggagggta 500

 acctgctggc tggagcggca gagcagtggc cttgatttgt cttttggaag 550

 attttaaaaa ccaaaaagca taaacattct ggtccttcag caatgctttc 600

 tctgaagaaa tacttaacgg aaggacttct ccagttcacc attctgctga 650

 gtttgattgg ggtacgggtg gacgtggata cttacctgac ctcacagctt 700

 cccccactcc gggagatcat cctggggccc agttctgcct atactcagac 750

 ccagttccac aacctgagga ataccttgga tggctatggt atccacccca 800

 agagcataga cctggacaat tacttcactg cccggcggct cctcagtcag 850

 gtgagggccc tggacaggtt ccaggtgcca accactgagg taaatgcctg 900

 gctggttcac cgagacccag aggggtctgt ctctggcagt cagcccaact 950

 caggcctcgc cctcgagagt tccagtggcc tccaagatgt gacaggccca 1000

 gacaacgggg tgcgagaaag cgaaacggag cagggattcg gtgaagattt 1050

 ggaggatttg ggggctgtag cccccccagt cagtggagac ttaaccaaag 1100

 aggacataga tctgattgac atcctttggc gacaggatat tgatctgggg 1150

 gctgggcgtg aggtttttga ctatagtcac cgccagaagg agcaggatgt 1200

 ggagaaggag ctgcgagatg gaggcgagca ggacacctgg gcaggcgagg 1250

 gcgcggaagc tctggcacgg aacctgctag tggatggaga gactggggag 1300

 agcttccctg cacaggtgcc tagtggggag gaccagacgg ccctgtccct 1350

 ggaagagtgc cttaggctgc tggaagccac ctgccccttt ggggagaatg 1400

 ctgagtttcc agcagacatt tccagcataa cagaagcagt gcctagtgag 1450

 agtgagcccc ctgctcttca aaacaacctc ttgtctcctc ttctgaccgg 1500

 gacagagtca ccatttgatt tggaacagca gtggcaagat ctcatgtcca 1550

 tcatggaaat gcaggccatg gaagtgaaca catcagcaag tgaaatcctg 1600

 tacagtgccc ctcctggaga cccactgagc accaactaca gccttgcccc 1650

 caacactccc atcaatcaga atgtcagcct gcatcaggcg tccctggggg 1700

 gctgcagcca ggacttctta ctcttcagcc ccgaggtgga aagcctgcct 1750

 gtggccagta gctccacgct gctcccgttg gcccccagca attctaccag 1800

 cctcaactcc accttcggct ccaccaacct gacagggctc ttctttccac 1850

 cccagctcaa tggcacagcc aatgacacag caggcccaga gctgcctgac 1900

 cctttggggg gtctgttaga tgaagctatg ttggatgaga tcagccttat 1950

 ggacctggcc attgaagaag gctttaaccc tgtgcaggcc tcccagctgg 2000

 aggaggaatt tgactctgac tcaggccttt ccttagactc gagccatagc 2050

 ccttcttccc taagcagctc tgaaggcagt tcttcctctt cttcctcctc 2100

 ctcttcctct tcttcctctg cttcttcctc tgcctcttcc tccttttctg 2150

 aggaaggtgc ggttggctac agctctgact ctgagaccct ggatctggaa 2200

 gaggccgagg gtgctgtggg ctaccagcct gagtattcca agttctgccg 2250

 catgagctac caggatccag ctcagctctc atgcctgccc tacctggagc 2300

 acgtgggcca caaccacaca tacaacatgg cacccagtgc cctggactca 2350

 gccgacctgc caccacccag tgccctcaag aaaggcagca aggagaagca 2400

 ggctgacttc ctggacaagc agatgagccg ggatgagcac cgagcccgag 2450

 ccatgaagat ccctttcacc aatgacaaaa tcatcaacct gcctgtggag 2500

 gagttcaatg aactgctgtc caaataccag ttgagtgaag cccagctgag 2550

 cctcatccga gacatccggc gccggggcaa gaacaagatg gcggcgcaga 2600

 actgccgcaa gcgcaagctg gacaccatcc tgaatctgga gcgtgatgtg 2650

 gaggacctgc agcgtgacaa agcccggctg ctgcgggaga aagtggagtt 2700

 cctgcgctcc ctgcgacaga tgaagcagaa ggtccagagc ctgtaccagg 2750

 aggtgtttgg gcggctgcga gatgagaacg gacgacccta ctcgcccagt 2800

 cagtatgcgc tccagtacgc cggggacggc agtgtcctcc tcatcccccg 2850

 cacgatggcc gaccagcagg cccggcggca ggagaggaag ccaaaggacc 2900

 ggagaaagtg agcctgggga agaagggggt ttgaagccca ccaagaccga 2950

 aactggagaa gggctggacc tggacctgga cctggaccta cagcggggac 3000

 ttaaatgcct tcttatccaa tatatcttct cagatgggat gactgcgggt 3050

 cagtgtacag gaagaggcag gcactggctg gctcagctcc actcgggtgg 3100

 agtggaagtg gccagaccat ttagacggac agggtcctca ccctacccct 3150

 ttcctgtgag gcaggggtgg tggtggagtt gctggaggta gaggagctat 3200

 gtggagcaaa ggccgacaga ggggaaggaa tggacctgtg agaggaaggg 3250

 aaggtggcag aaagtctcat ttcaggaagg agggatagaa ggaaggaagg 3300

 aaggaacccc cccccccccc cgaaaaaaaa atcaaagcgg gaagaaaatc 3350

 agagggaagg ttaaggttgg ctctggccag gattccaggc agcaggttgg 3400

 agtgactggt gggcctagat cactggtgtg ataaacccca tttcaccccg 3450

 gggggggtgg ggtacacaga cacagggtgg gggtggggag gggcggtgtt 3500

 aactctttct gctccttgca ttttgacatc cctgaagggg agctcttgga 3550

 tatcattggc catgtttcaa tcgaatggag ccactgggcc ccaacactgg 3600

 ctttgagatt tagagtcaaa gggtagagtg aacaggaaag ggtcacgtgg 3650

 tcccatgttg caacagcccc aacatcacgc atgtcattca ctgccttgcc 3700

 actccatctc cctccgtgct ccagccaccc ctgagctgag gctcccattg 3750

 tctccatcag agcctgcatg tgtatgccgt cctcccctgg tccggtgttt 3800

 gtgttcccca cccctcacag actgcctgag ctcttctgta agctggggta 3850

 gggtgatggc agtgctccgg gaactgggcc tgcagccttc ctcttctggg 3900

 actgctgtga ggcagaggaa tgatggagaa tctagtgtag cagcctccag 3950

 gcaggattca gcacaacact ggggagtcac ccttccctcg ggcctctgcc 4000

 taccaacaac tgggcttatc actgggaaaa cacaaaaaat tacacaaccc 4050

 agcaacaaca aaagaactag tcctcttaga atttcttgcg ctttgatttt 4100

 tttagggctt gtgccctgtt tcacttatag ggtctagaat gcttgtgttg 4150

 agtaaaaagg agattcccaa tattcaaagc tgctaaatgt tctctttgcc 4200

 ataaagactc cgtgtaactg tgtgaacact tgggattttt ctcctctgtc 4250

 ccgaggtcgt cgtctgcttt cttttttggg tttctttcta gaagattgag 4300

 aagtgcatat gacaggctga gagcacctcc ccaaacacac aagctctcag 4350

 ccacaggcag cttctccaca gccccagctt cgcacaggct cctggagggc 4400

 tgcctggggg aggcagacat gggagtgcca aggtggccag atggttccag 4450

 gactacaatg tctttatttt taactgtttg ccactgctgc cctcacccct 4500

 gcccggctct ggagtaccgt ctgccccaga caagtgggag tgaaatgggg 4550

 gtggggggaa gcactgattc ccagttaggg ggtgcctaac tgagcagtag 4600

 ggatagaagg tgtgaacctg ggagtgcttt tataaattat tttccttgta 4650

 gattttattt ttaatttatc tctgtgacct gccagggaga ggggagagag 4700

 agagagatgc tgttgagcac atgacaaaat aaaataaaat ggatgattca 4750

 aaaaaaaaaa 4760

<210> 2883
<211> 772
<212> PRT
<213> Homo sapien

<400> 2883
 Met Leu Ser Leu Lys Lys Tyr Leu Thr Glu Gly Leu Leu Gln Phe
   1               5                  10                  15

 Thr Ile Leu Leu Ser Leu Ile Gly Val Arg Val Asp Val Asp Thr
                  20                  25                  30

 Tyr Leu Thr Ser Gln Leu Pro Pro Leu Arg Glu Ile Ile Leu Gly
                  35                  40                  45

 Pro Ser Ser Ala Tyr Thr Gln Thr Gln Phe His Asn Leu Arg Asn
                  50                  55                  60

 Thr Leu Asp Gly Tyr Gly Ile His Pro Lys Ser Ile Asp Leu Asp
                  65                  70                  75

 Asn Tyr Phe Thr Ala Arg Arg Leu Leu Ser Gln Val Arg Ala Leu
                  80                  85                  90

 Asp Arg Phe Gln Val Pro Thr Thr Glu Val Asn Ala Trp Leu Val
                  95                 100                 105

 His Arg Asp Pro Glu Gly Ser Val Ser Gly Ser Gln Pro Asn Ser
                 110                 115                 120

 Gly Leu Ala Leu Glu Ser Ser Ser Gly Leu Gln Asp Val Thr Gly
                 125                 130                 135

 Pro Asp Asn Gly Val Arg Glu Ser Glu Thr Glu Gln Gly Phe Gly
                 140                 145                 150

 Glu Asp Leu Glu Asp Leu Gly Ala Val Ala Pro Pro Val Ser Gly
                 155                 160                 165

 Asp Leu Thr Lys Glu Asp Ile Asp Leu Ile Asp Ile Leu Trp Arg
                 170                 175                 180

 Gln Asp Ile Asp Leu Gly Ala Gly Arg Glu Val Phe Asp Tyr Ser
                 185                 190                 195

 His Arg Gln Lys Glu Gln Asp Val Glu Lys Glu Leu Arg Asp Gly
                 200                 205                 210

 Gly Glu Gln Asp Thr Trp Ala Gly Glu Gly Ala Glu Ala Leu Ala
                 215                 220                 225

 Arg Asn Leu Leu Val Asp Gly Glu Thr Gly Glu Ser Phe Pro Ala
                 230                 235                 240

 Gln Val Pro Ser Gly Glu Asp Gln Thr Ala Leu Ser Leu Glu Glu
                 245                 250                 255

 Cys Leu Arg Leu Leu Glu Ala Thr Cys Pro Phe Gly Glu Asn Ala
                 260                 265                 270

 Glu Phe Pro Ala Asp Ile Ser Ser Ile Thr Glu Ala Val Pro Ser
                 275                 280                 285

 Glu Ser Glu Pro Pro Ala Leu Gln Asn Asn Leu Leu Ser Pro Leu
                 290                 295                 300

 Leu Thr Gly Thr Glu Ser Pro Phe Asp Leu Glu Gln Gln Trp Gln
                 305                 310                 315

 Asp Leu Met Ser Ile Met Glu Met Gln Ala Met Glu Val Asn Thr
                 320                 325                 330

 Ser Ala Ser Glu Ile Leu Tyr Ser Ala Pro Pro Gly Asp Pro Leu
                 335                 340                 345

 Ser Thr Asn Tyr Ser Leu Ala Pro Asn Thr Pro Ile Asn Gln Asn
                 350                 355                 360

 Val Ser Leu His Gln Ala Ser Leu Gly Gly Cys Ser Gln Asp Phe
                 365                 370                 375

 Leu Leu Phe Ser Pro Glu Val Glu Ser Leu Pro Val Ala Ser Ser
                 380                 385                 390

 Ser Thr Leu Leu Pro Leu Ala Pro Ser Asn Ser Thr Ser Leu Asn
                 395                 400                 405

 Ser Thr Phe Gly Ser Thr Asn Leu Thr Gly Leu Phe Phe Pro Pro
                 410                 415                 420

 Gln Leu Asn Gly Thr Ala Asn Asp Thr Ala Gly Pro Glu Leu Pro
                 425                 430                 435

 Asp Pro Leu Gly Gly Leu Leu Asp Glu Ala Met Leu Asp Glu Ile
                 440                 445                 450

 Ser Leu Met Asp Leu Ala Ile Glu Glu Gly Phe Asn Pro Val Gln
                 455                 460                 465

 Ala Ser Gln Leu Glu Glu Glu Phe Asp Ser Asp Ser Gly Leu Ser
                 470                 475                 480

 Leu Asp Ser Ser His Ser Pro Ser Ser Leu Ser Ser Ser Glu Gly
                 485                 490                 495

 Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ala
                 500                 505                 510

 Ser Ser Ser Ala Ser Ser Ser Phe Ser Glu Glu Gly Ala Val Gly
                 515                 520                 525

 Tyr Ser Ser Asp Ser Glu Thr Leu Asp Leu Glu Glu Ala Glu Gly
                 530                 535                 540

 Ala Val Gly Tyr Gln Pro Glu Tyr Ser Lys Phe Cys Arg Met Ser
                 545                 550                 555

 Tyr Gln Asp Pro Ala Gln Leu Ser Cys Leu Pro Tyr Leu Glu His
                 560                 565                 570

 Val Gly His Asn His Thr Tyr Asn Met Ala Pro Ser Ala Leu Asp
                 575                 580                 585

 Ser Ala Asp Leu Pro Pro Pro Ser Ala Leu Lys Lys Gly Ser Lys
                 590                 595                 600

 Glu Lys Gln Ala Asp Phe Leu Asp Lys Gln Met Ser Arg Asp Glu
                 605                 610                 615

 His Arg Ala Arg Ala Met Lys Ile Pro Phe Thr Asn Asp Lys Ile
                 620                 625                 630

 Ile Asn Leu Pro Val Glu Glu Phe Asn Glu Leu Leu Ser Lys Tyr
                 635                 640                 645

 Gln Leu Ser Glu Ala Gln Leu Ser Leu Ile Arg Asp Ile Arg Arg
                 650                 655                 660

 Arg Gly Lys Asn Lys Met Ala Ala Gln Asn Cys Arg Lys Arg Lys
                 665                 670                 675

 Leu Asp Thr Ile Leu Asn Leu Glu Arg Asp Val Glu Asp Leu Gln
                 680                 685                 690

 Arg Asp Lys Ala Arg Leu Leu Arg Glu Lys Val Glu Phe Leu Arg
                 695                 700                 705

 Ser Leu Arg Gln Met Lys Gln Lys Val Gln Ser Leu Tyr Gln Glu
                 710                 715                 720

 Val Phe Gly Arg Leu Arg Asp Glu Asn Gly Arg Pro Tyr Ser Pro
                 725                 730                 735

 Ser Gln Tyr Ala Leu Gln Tyr Ala Gly Asp Gly Ser Val Leu Leu
                 740                 745                 750

 Ile Pro Arg Thr Met Ala Asp Gln Gln Ala Arg Arg Gln Glu Arg
                 755                 760                 765

 Lys Pro Lys Asp Arg Arg Lys
                 770

<210> 2884
<211> 3502
<212> DNA
<213> Homo sapien

<400> 2884
 acatgacagc agatccgcgg aagggcagaa tgggactcca agcctgcctc 50

 ctagggctct ttgccctcat cctctctggc aaatgcagtt acagcccgga 100

 gcccgaccag cggaggacgc tgcccccagg ctgggtgtcc ctgggccgtg 150

 cggaccctga ggaagagctg agtctcacct ttgccctgag acagcagaat 200

 gtggaaagac tctcggagct ggtgcaggct gtgtcggatc ccagctctcc 250

 tcaatacgga aaatacctga ccctagagaa tgtggctgat ctggtgaggc 300

 catccccact gaccctccac acggtgcaaa aatggctctt ggcagccgga 350

 gcccagaagt gccattctgt gatcacacag gactttctga cttgctggct 400

 gagcatccga caagcagagc tgctgctccc tggggctgag tttcatcact 450

 atgtgggagg acctacggaa acccatgttg taaggtcccc acatccctac 500

 cagcttccac aggccttggc cccccatgtg gactttgtgg ggggactgca 550

 ccgttttccc ccaacatcat ccctgaggca acgtcctgag ccgcaggtga 600

 cagggactgt aggcctgcat ctgggggtaa ccccctctgt gatccgtaag 650

 cgatacaact tgacctcaca agacgtgggc tctggcacca gcaataacag 700

 ccaagcctgt gcccagttcc tggagcagta tttccatgac tcagacctgg 750

 ctcagttcat gcgcctcttc ggtggcaact ttgcacatca ggcatcagta 800

 gcccgtgtgg ttggacaaca gggccggggc cgggccggga ttgaggccag 850

 tctagatgtg cagtacctga tgagtgctgg tgccaacatc tccacctggg 900

 tctacagtag ccctggccgg catgagggac aggagccctt cctgcagtgg 950

 ctcatgctgc tcagtaatga gtcagccctg ccacatgtgc atactgtgag 1000

 ctatggagat gatgaggact ccctcagcag cgcctacatc cagcgggtca 1050

 acactgagct catgaaggct gccgctcggg gtctcaccct gctcttcgcc 1100

 tcaggtgaca gtggggccgg gtgttggtct gtctctggaa gacaccagtt 1150

 ccgccctacc ttccctgcct ccagccccta tgtcaccaca gtgggaggca 1200

 catccttcca ggaacctttc ctcatcacaa atgaaattgt tgactatatc 1250

 agtggtggtg gcttcagcaa tgtgttccca cggccttcat accaggagga 1300

 agctgtaacg aagttcctga gctctagccc ccacctgcca ccatccagtt 1350

 acttcaatgc cagtggccgt gcctacccag atgtggctgc actttctgat 1400

 ggctactggg tggtcagcaa cagagtgccc attccatggg tgtccggaac 1450

 ctcggcctct actccagtgt ttggggggat cctatccttg atcaatgagc 1500

 acaggatcct tagtggccgc ccccctcttg gctttctcaa cccaaggctc 1550

 taccagcagc atggggcagg actctttgat gtaacccgtg gctgccatga 1600

 gtcctgtctg gatgaagagg tagagggcca gggtttctgc tctggtcctg 1650

 gctgggatcc tgtaacaggc tggggaacac ccaacttccc agctttgctg 1700

 aagactctac tcaacccctg accctttcct atcaggagag atggcttgtc 1750

 ccctgccctg aagctggcag ttcagtccct tattctgccc tgttggaagc 1800

 cctgctgaac cctcaactat tgactgctgc agacagctta tctccctaac 1850

 cctgaaatgc ggtgagcttg acttgactcc caaccctacc atgctccatc 1900

 atactcaggt ctccctactc ctgccttaga ttcctcaata agatgctgta 1950

 actagcattt tttgaatgcc tctccctccg catctcatct ttctcttttc 2000

 aatcaggctt ttccaaaggg ttgtatacag actctgtgca ctatttcact 2050

 tgatattcat tccccaattc actgcaagga gacctctact gtcaccgttt 2100

 actctttcct accctgacat ccagaaacaa tggcctccag tgcatacttc 2150

 tcaatctttg ctttatggcc tttccatcat agttgcccac tccctctcct 2200

 tacttagctt ccaggtctta acttctctga ctactcttgt cttcctctct 2250

 catcaatttc tgcttcttca tggaatgctg accttcattg ctccatttgt 2300

 agatttttgc tcttctcagt ttactcattg tcccctggaa caaatcactg 2350

 acatctacaa ccattaccat ctcactaaat aagactttct atccaataat 2400

 gattgatacc tcaaatgtaa gatgcgtgat actcaacatt tcatcgtcca 2450

 ccttcccaac cccaaacaat tccatctcgt ttcttcttgg taaatgatgc 2500

 tatgcttttt ccaaccaagc cagaaacctg tgtcatcttt tcaccccacc 2550

 ttcaatcaac aagtcctcaa tcaacaagtc ctactgactg cacatcttaa 2600

 atatatcttt atcagtccac aagtccttcc aattatattt cccaagtata 2650

 tctagaactt atccacttat atccccactg ctactacctt agtttagggc 2700

 tatattctct tgaaaaaaag tgtccttact tcctgccaat ccccaagtca 2750

 tcttccagag taaaatgcaa atcccatcag gccacttgga tgaaaaccct 2800

 tcaaggatta ctggatagaa ttcaggcttt cccctccagc ccccaatcat 2850

 agctcacaaa ccttccttgc tatttgttct taagtaaaaa atcatttttc 2900

 ctcctccctc cccaaacccc aaggaactct cactcttgct caagctgttc 2950

 cgtcccctta ccacccctga tacaactgcc aggttaattt ccagaattct 3000

 tgcaagactc agttcagaag tcaccttctt tcgtgaatgt tttgattccc 3050

 tgaggctact ttattttggt atggctgaaa aatcctagat tttctaaaca 3100

 aaacctgttt gaatcttggt tctgatatgg actaggagag agactgggtc 3150

 aagtaagctt atctccctga ggctgtttcc tcgtctgtta agtgtgaata 3200

 tcaatacctg cctttcataa tcaccaggga ataaagtgga ataatgttga 3250

 taacagtgct tggcacctgg aagtaggtgg cagatgttaa cgcccttcct 3300

 cccttgcact gcgccccctg tgcctacctc tagcattgta acgaccacat 3350

 agtattgaaa tggccagttt acttgtctgc cttcctttcc aagaccgttg 3400

 gtgcctagag gactagaatc gtgtcctatt taactttgtg ttcccaggtc 3450

 ctagctcagg agttggcaaa taagaattaa atgtctgcta caccgaaaca 3500

 aa 3502

<210> 2885
<211> 563
<212> PRT
<213> Homo sapien

<400> 2885
 Met Gly Leu Gln Ala Cys Leu Leu Gly Leu Phe Ala Leu Ile Leu
   1               5                  10                  15

 Ser Gly Lys Cys Ser Tyr Ser Pro Glu Pro Asp Gln Arg Arg Thr
                  20                  25                  30

 Leu Pro Pro Gly Trp Val Ser Leu Gly Arg Ala Asp Pro Glu Glu
                  35                  40                  45

 Glu Leu Ser Leu Thr Phe Ala Leu Arg Gln Gln Asn Val Glu Arg
                  50                  55                  60

 Leu Ser Glu Leu Val Gln Ala Val Ser Asp Pro Ser Ser Pro Gln
                  65                  70                  75

 Tyr Gly Lys Tyr Leu Thr Leu Glu Asn Val Ala Asp Leu Val Arg
                  80                  85                  90

 Pro Ser Pro Leu Thr Leu His Thr Val Gln Lys Trp Leu Leu Ala
                  95                 100                 105

 Ala Gly Ala Gln Lys Cys His Ser Val Ile Thr Gln Asp Phe Leu
                 110                 115                 120

 Thr Cys Trp Leu Ser Ile Arg Gln Ala Glu Leu Leu Leu Pro Gly
                 125                 130                 135

 Ala Glu Phe His His Tyr Val Gly Gly Pro Thr Glu Thr His Val
                 140                 145                 150

 Val Arg Ser Pro His Pro Tyr Gln Leu Pro Gln Ala Leu Ala Pro
                 155                 160                 165

 His Val Asp Phe Val Gly Gly Leu His Arg Phe Pro Pro Thr Ser
                 170                 175                 180

 Ser Leu Arg Gln Arg Pro Glu Pro Gln Val Thr Gly Thr Val Gly
                 185                 190                 195

 Leu His Leu Gly Val Thr Pro Ser Val Ile Arg Lys Arg Tyr Asn
                 200                 205                 210

 Leu Thr Ser Gln Asp Val Gly Ser Gly Thr Ser Asn Asn Ser Gln
                 215                 220                 225

 Ala Cys Ala Gln Phe Leu Glu Gln Tyr Phe His Asp Ser Asp Leu
                 230                 235                 240

 Ala Gln Phe Met Arg Leu Phe Gly Gly Asn Phe Ala His Gln Ala
                 245                 250                 255

 Ser Val Ala Arg Val Val Gly Gln Gln Gly Arg Gly Arg Ala Gly
                 260                 265                 270

 Ile Glu Ala Ser Leu Asp Val Gln Tyr Leu Met Ser Ala Gly Ala
                 275                 280                 285

 Asn Ile Ser Thr Trp Val Tyr Ser Ser Pro Gly Arg His Glu Gly
                 290                 295                 300

 Gln Glu Pro Phe Leu Gln Trp Leu Met Leu Leu Ser Asn Glu Ser
                 305                 310                 315

 Ala Leu Pro His Val His Thr Val Ser Tyr Gly Asp Asp Glu Asp
                 320                 325                 330

 Ser Leu Ser Ser Ala Tyr Ile Gln Arg Val Asn Thr Glu Leu Met
                 335                 340                 345

 Lys Ala Ala Ala Arg Gly Leu Thr Leu Leu Phe Ala Ser Gly Asp
                 350                 355                 360

 Ser Gly Ala Gly Cys Trp Ser Val Ser Gly Arg His Gln Phe Arg
                 365                 370                 375

 Pro Thr Phe Pro Ala Ser Ser Pro Tyr Val Thr Thr Val Gly Gly
                 380                 385                 390

 Thr Ser Phe Gln Glu Pro Phe Leu Ile Thr Asn Glu Ile Val Asp
                 395                 400                 405

 Tyr Ile Ser Gly Gly Gly Phe Ser Asn Val Phe Pro Arg Pro Ser
                 410                 415                 420

 Tyr Gln Glu Glu Ala Val Thr Lys Phe Leu Ser Ser Ser Pro His
                 425                 430                 435

 Leu Pro Pro Ser Ser Tyr Phe Asn Ala Ser Gly Arg Ala Tyr Pro
                 440                 445                 450

 Asp Val Ala Ala Leu Ser Asp Gly Tyr Trp Val Val Ser Asn Arg
                 455                 460                 465

 Val Pro Ile Pro Trp Val Ser Gly Thr Ser Ala Ser Thr Pro Val
                 470                 475                 480

 Phe Gly Gly Ile Leu Ser Leu Ile Asn Glu His Arg Ile Leu Ser
                 485                 490                 495

 Gly Arg Pro Pro Leu Gly Phe Leu Asn Pro Arg Leu Tyr Gln Gln
                 500                 505                 510

 His Gly Ala Gly Leu Phe Asp Val Thr Arg Gly Cys His Glu Ser
                 515                 520                 525

 Cys Leu Asp Glu Glu Val Glu Gly Gln Gly Phe Cys Ser Gly Pro
                 530                 535                 540

 Gly Trp Asp Pro Val Thr Gly Trp Gly Thr Pro Asn Phe Pro Ala
                 545                 550                 555

 Leu Leu Lys Thr Leu Leu Asn Pro
                 560

<210> 2886
<211> 1084
<212> DNA
<213> Homo sapien

<400> 2886
 cgaggatgtg cgtgggggct cggcggctgg gccgcgggcc gtgtgcggct 50

 ctgctcctcc tgggcctggg gctgagcacc gtgacggggc tccactgtgt 100

 cggggacacc taccccagca acgaccggtg ctgccacgag tgcaggccag 150

 gcaacgggat ggtgagccgc tgcagccgct cccagaacac ggtgtgccgt 200

 ccgtgcgggc cgggcttcta caacgacgtg gtcagctcca agccgtgcaa 250

 gccctgcacg tggtgtaacc tcagaagtgg gagtgagcgg aagcagctgt 300

 gcacggccac acaggacaca gtctgccgct gccgggcggg cacccagccc 350

 ctggacagct acaagcctgg agttgactgt gccccctgcc ctccagggca 400

 cttctcccca ggcgacaacc aggcctgcaa gccctggacc aactgcacct 450

 tggctgggaa gcacaccctg cagccggcca gcaatagctc ggacgcaatc 500

 tgtgaggaca gggacccccc agccacgcag ccccaggaga cccagggccc 550

 cccggccagg cccatcactg tccagcccac tgaagcctgg cccagaacct 600

 cacagggacc ctccacccgg cccgtggagg tccccggggg ccgtgcggtt 650

 gccgccatcc tgggcctggg cctggtgctg gggctgctgg gccccctggc 700

 catcctgctg gccctgtacc tgctccggag ggaccagagg ctgccccccg 750

 atgcccacaa gccccctggg ggaggcagtt tccggacccc catccaagag 800

 gagcaggccg acgcccactc caccctggcc aagatctgac ctgggcccac 850

 caaggtggac gctgggcccc gccaggctgg agcccggagg gtctgctggg 900

 cgagcagggc aggtgcaggc cgcctgcccc gccacgctcc tgggccaact 950

 ctgcaccgtt ctaggtgccg atggctgcct ccggctctct gcttacgtat 1000

 gccatgcata cctcctgccc cgcgggacca caataaaaac cttggcagac 1050

 gggagtctcc gaccggcaaa aaaaaaaaaa aaaa 1084

<210> 2887
<211> 277
<212> PRT
<213> Homo sapien

<400> 2887
 Met Cys Val Gly Ala Arg Arg Leu Gly Arg Gly Pro Cys Ala Ala
   1               5                  10                  15

 Leu Leu Leu Leu Gly Leu Gly Leu Ser Thr Val Thr Gly Leu His
                  20                  25                  30

 Cys Val Gly Asp Thr Tyr Pro Ser Asn Asp Arg Cys Cys His Glu
                  35                  40                  45

 Cys Arg Pro Gly Asn Gly Met Val Ser Arg Cys Ser Arg Ser Gln
                  50                  55                  60

 Asn Thr Val Cys Arg Pro Cys Gly Pro Gly Phe Tyr Asn Asp Val
                  65                  70                  75

 Val Ser Ser Lys Pro Cys Lys Pro Cys Thr Trp Cys Asn Leu Arg
                  80                  85                  90

 Ser Gly Ser Glu Arg Lys Gln Leu Cys Thr Ala Thr Gln Asp Thr
                  95                 100                 105

 Val Cys Arg Cys Arg Ala Gly Thr Gln Pro Leu Asp Ser Tyr Lys
                 110                 115                 120

 Pro Gly Val Asp Cys Ala Pro Cys Pro Pro Gly His Phe Ser Pro
                 125                 130                 135

 Gly Asp Asn Gln Ala Cys Lys Pro Trp Thr Asn Cys Thr Leu Ala
                 140                 145                 150

 Gly Lys His Thr Leu Gln Pro Ala Ser Asn Ser Ser Asp Ala Ile
                 155                 160                 165

 Cys Glu Asp Arg Asp Pro Pro Ala Thr Gln Pro Gln Glu Thr Gln
                 170                 175                 180

 Gly Pro Pro Ala Arg Pro Ile Thr Val Gln Pro Thr Glu Ala Trp
                 185                 190                 195

 Pro Arg Thr Ser Gln Gly Pro Ser Thr Arg Pro Val Glu Val Pro
                 200                 205                 210

 Gly Gly Arg Ala Val Ala Ala Ile Leu Gly Leu Gly Leu Val Leu
                 215                 220                 225

 Gly Leu Leu Gly Pro Leu Ala Ile Leu Leu Ala Leu Tyr Leu Leu
                 230                 235                 240

 Arg Arg Asp Gln Arg Leu Pro Pro Asp Ala His Lys Pro Pro Gly
                 245                 250                 255

 Gly Gly Ser Phe Arg Thr Pro Ile Gln Glu Glu Gln Ala Asp Ala
                 260                 265                 270

 His Ser Thr Leu Ala Lys Ile
                 275

<210> 2888
<211> 1541
<212> DNA
<213> Homo sapien

<400> 2888
 aaaaaaaaag aaaacaatga aggaaaagga gggtgagtta gctggagtag 50

 aatagaggta tagaatcgtt cctaaataac cggctgcatt ggtttcctgg 100

 agacttgcta aaaacccaga ttcccaggcc ccacttcttg gtgctcctaa 150

 ttcagtagca tcacagtagg gttccagaag cggtattttt aacaagctcc 200

 caggtaattc tgatgtgcac ctagatttgg aaatcactgt gttaaaaaat 250

 attgtgaggt aagttggtca gttaggttgg gcagctttta tttcattgct 300

 aagggatttg gacttgatgg tgtaataaag cattaattga acaaatattt 350

 atggagcctg tactatgtac cagatgcaga ctgtgctagc ggttggggat 400

 acagtgatga cttggtctgc ctctaggtgg cagggagcca ttttgggttt 450

 tcgaacagaa aagtgacata atgaatgctg agttcttagg aagattaatc 500

 caggagtagt ctccaggatg tactggaagg agagaagctg aaagcaggga 550

 ggctgctgtg tttgcagttg gctgcccagt gctacctctg cagagacaat 600

 caatgtcctg aaggtagctg gtatgtctgt gtgcactgac acgagccttc 650

 ctaccaagcc ccaggggctc catgctggag aatgcacgta gggctagggt 700

 gagcactaac ttcacttcag gagagcaagg aacagtgtgg ctcttccatt 750

 tttcagttct gtaagcacat cacccttttc tcctcccctt gagctgtgtt 800

 ctctgacagc tgtttgttgg taaagccagc agcccctaaa gcacgtccca 850

 gccttgtctc ctctgtgctt tcccccacca ctgctgctgc acgcctcatt 900

 tgctgggcca ctttagtggt ggaaccatta gaggctgagt gacttaaagg 950

 agattgagtc tgtctcgacc ccgagagaga gtgggatgga tggatgcatc 1000

 gtctcattta gaaagtgttg cctctgactc taacacactc ttctctcttt 1050

 ctttacctcc ctccctgtct tcctcccttc ccctcctttc cctaaccccc 1100

 ttccctcccc ctttctcctt ctctctcaca gtgtaggcac cacttctctt 1150

 acaatttagg ctttctctct gccttgggct gagtgaggaa gaggagtgct 1200

 gttcctgcct tcctagccca gctgggtctg accagaggct actgtgtacc 1250

 catttaccat gcgtgattgt taactcagag tggggtgtag ccaggtattg 1300

 actgaatgta tgttcttgct gacctgtgtt tttttctgta gggaccaaag 1350

 cagtatcctt acaataatct gtacctggaa cgaggcggtg atccctccaa 1400

 agaaccagag cgggtggttc actatgagat ctgaggaggc ttcgtgggct 1450

 tttgggtcct ctaactagga ctccctcatt cctagaaatt taaccttaat 1500

 gaaatcccta ataaaactca gtgctgtgtt atttgtgcct c 1541

<210> 2889
<211> 13
<212> PRT
<213> Homo sapien

<400> 2889
 Met Lys Ser Leu Ile Lys Leu Ser Ala Val Leu Phe Val
   1               5                  10

<210> 2890
<211> 1952
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1502, 1505
<223> Unknown base

<400> 2890
 cagaacccag aaaaacaact cattcgcttt catttcctca ctgactataa 50

 aagaatagag aaggaagggc ttcagtgacc ggctgcctgg ctgacttaca 100

 gcagtcagac tctgacagga tcatggctat gatggaggtc caggggggac 150

 ccagcctggg acagacctgc gtgctgatcg tgatcttcac agtgctcctg 200

 cagtctctct gtgtggctgt aacttacgtg tactttacca acgagctgaa 250

 gcagatgcag gacaagtact ccaaaagtgg cattgcttgt ttcttaaaag 300

 aagatgacag ttattgggac cccaatgacg aagagagtat gaacagcccc 350

 tgctggcaag tcaagtggca actccgtcag ctcgttagaa agatgatttt 400

 gagaacctct gaggaaacca tttctacagt tcaagaaaag caacaaaata 450

 tttctcccct agtgagagaa agaggtcctc agagagtagc agctcacata 500

 actgggacca gaggaagaag caacacattg tcttctccaa actccaagaa 550

 tgaaaaggct ctgggccgca aaataaactc ctgggaatca tcaaggagtg 600

 ggcattcatt cctgagcaac ttgcacttga ggaatggtga actggtcatc 650

 catgaaaaag ggttttacta catctattcc caaacatact ttcgatttca 700

 ggaggaaata aaagaaaaca caaagaacga caaacaaatg gtccaatata 750

 tttacaaata cacaagttat cctgacccta tattgttgat gaaaagtgct 800

 agaaatagtt gttggtctaa agatgcagaa tatggactct attccatcta 850

 tcaaggggga atatttgagc ttaaggaaaa tgacagaatt tttgtttctg 900

 taacaaatga gcacttgata gacatggacc atgaagccag ttttttcggg 950

 gcctttttag ttggctaact gacctggaaa gaaaaagcaa taacctcaaa 1000

 gtgactattc agttttcagg atgatacact atgaagatgt ttcaaaaaat 1050

 ctgaccaaaa caaacaaaca gaaaacagaa aacaaaaaaa cctctatgca 1100

 atctgagtag agcagccaca accaaaaaat tctacaacac acactgttct 1150

 gaaagtgact cacttatccc aagagaatga aattgctgaa agatctttca 1200

 ggactctacc tcatatcagt ttgctagcag aaatctagaa gactgtcagc 1250

 ttccaaacat taatgcaatg gttaacatct tctgtcttta taatctactc 1300

 cttgtaaaga ctgtagaaga aagcgcaaca atccatctct caagtagtgt 1350

 atcacagtag tagcctccag gtttccttaa gggacaacat ccttaagtca 1400

 aaagagagaa gaggcaccac taaaagatcg cagtttgcct ggtgcagtgg 1450

 ctcacacctg taatcccaac attttgggaa cccaaggtgg gtagatccac 1500

 cnagntcaag agatcaaaga ccatagtgac caacatagtg aaaccccatc 1550

 tctactgaaa gtacaaaaat tagctgggtg tgttggcaca tgcctgtagt 1600

 cccagctact tgagaggctg aggcaagaga attgtttgaa cccgggaggc 1650

 agaggttgca gtgtggtgag atcatgccac tacactccag cctggcgaca 1700

 gagcgagact tggtttcaaa aaaaaaaaaa aaaacttcag taagtacgtg 1750

 ttattttttt caataaaatt ctattacagt atgtcatgtt tgctgtagtg 1800

 ctcatattta ttgttgtttt tgttttagta ctcacttgtt tcataatatc 1850

 aagattacta aaaatggggg aaaggacttc taatcttttt ttcataatat 1900

 ctttgacaca tattacagaa gaaataaatt tcttactttt aatttaatat 1950

 ga 1952

<210> 2891
<211> 321
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1502, 1505
<223> Unknown amino acid

<400> 2891
 Gln Asn Pro Glu Lys Gln Leu Ile Arg Phe His Phe Leu Thr Asp
   1               5                  10                  15

 Tyr Lys Arg Ile Glu Lys Glu Gly Leu Gln Thr Gly Cys Leu Ala
                  20                  25                  30

 Asp Leu Gln Gln Ser Asp Ser Asp Arg Ile Met Ala Met Met Glu
                  35                  40                  45

 Val Gln Gly Gly Pro Ser Leu Gly Gln Thr Cys Val Leu Ile Val
                  50                  55                  60

 Ile Phe Thr Val Leu Leu Gln Ser Leu Cys Val Ala Val Thr Tyr
                  65                  70                  75

 Val Tyr Phe Thr Asn Glu Leu Lys Gln Met Gln Asp Lys Tyr Ser
                  80                  85                  90

 Lys Ser Gly Ile Ala Cys Phe Leu Lys Glu Asp Asp Ser Tyr Trp
                  95                 100                 105

 Asp Pro Asn Asp Glu Glu Ser Met Asn Ser Pro Cys Trp Gln Val
                 110                 115                 120

 Lys Trp Gln Leu Arg Gln Leu Val Arg Lys Met Ile Leu Arg Thr
                 125                 130                 135

 Ser Glu Glu Thr Ile Ser Thr Val Gln Glu Lys Gln Gln Asn Ile
                 140                 145                 150

 Ser Pro Leu Val Arg Glu Arg Gly Pro Gln Arg Val Ala Ala His
                 155                 160                 165

 Ile Thr Gly Thr Arg Gly Arg Ser Asn Thr Leu Ser Ser Pro Asn
                 170                 175                 180

 Ser Lys Asn Glu Lys Ala Leu Gly Arg Lys Ile Asn Ser Trp Glu
                 185                 190                 195

 Ser Ser Arg Ser Gly His Ser Phe Leu Ser Asn Leu His Leu Arg
                 200                 205                 210

 Asn Gly Glu Leu Val Ile His Glu Lys Gly Phe Tyr Tyr Ile Tyr
                 215                 220                 225

 Ser Gln Thr Tyr Phe Arg Phe Gln Glu Glu Ile Lys Glu Asn Thr
                 230                 235                 240

 Lys Asn Asp Lys Gln Met Val Gln Tyr Ile Tyr Lys Tyr Thr Ser
                 245                 250                 255

 Tyr Pro Asp Pro Ile Leu Leu Met Lys Ser Ala Arg Asn Ser Cys
                 260                 265                 270

 Trp Ser Lys Asp Ala Glu Tyr Gly Leu Tyr Ser Ile Tyr Gln Gly
                 275                 280                 285

 Gly Ile Phe Glu Leu Lys Glu Asn Asp Arg Ile Phe Val Ser Val
                 290                 295                 300

 Thr Asn Glu His Leu Ile Asp Met Asp His Glu Ala Ser Phe Phe
                 305                 310                 315

 Gly Ala Phe Leu Val Gly
                 320

<210> 2892
<211> 1486
<212> DNA
<213> Homo sapien

<400> 2892
 ggccgcggcg gcggaggcag cagcggcggc ggcagtggcg gcggcgaagg 50

 tggcggcggc tcggccagta ctcccggccc ccgccatttc ggactgggag 100

 cgagcgcggc gcaggcactg aaggcggcgg cggggccaga ggctcagcgg 150

 ctcccaggtg cgggagagag gcctgctgaa aatgactgaa tataaacttg 200

 tggtagttgg agctggtggc gtaggcaaga gtgccttgac gatacagcta 250

 attcagaatc attttgtgga cgaatatgat ccaacaatag aggattccta 300

 caggaagcaa gtagtaattg atggagaaac ctgtctcttg gatattctcg 350

 acacagcagg tcaagaggag tacagtgcaa tgagggacca gtacatgagg 400

 actggggagg gctttctttg tgtatttgcc ataaataata ctaaatcatt 450

 tgaagatatt caccattata gagaacaaat taaaagagtt aaggactctg 500

 aagatgtacc tatggtccta gtaggaaata aatgtgattt gccttctaga 550

 acagtagaca caaaacaggc tcaggactta gcaagaagtt atggaattcc 600

 ttttattgaa acatcagcaa agacaagaca gagagtggag gatgcttttt 650

 atacattggt gagagagatc cgacaataca gattgaaaaa aatcagcaaa 700

 gaagaaaaga ctcctggctg tgtgaaaatt aaaaaatgca ttataatgta 750

 atctgggtgt tgatgatgcc ttctatacat tagttcgaga aattcgaaaa 800

 cataaagaaa agatgagcaa agatggtaaa aagaagaaaa agaagtcaaa 850

 gacaaagtgt gtaattatgt aaatacaatt tgtacttttt tcttaaggca 900

 tactagtaca agtggtaatt tttgtacatt acactaaatt attagcattt 950

 gttttagcat tacctaattt ttttcctgct ccatgcagac tgttagcttt 1000

 taccttaaat gcttatttta aaatgacagt ggaagttttt ttttcctcga 1050

 agtgccagta ttcccagagt tttggttttt gaactagcaa tgcctgtgaa 1100

 aaagaaactg aatacctaag atttctgtct tggggttttt ggtgcatgca 1150

 gttgattact tcttattttt cttaccaagt gtgaatgttg gtgtgaaaca 1200

 aattaatgaa gcttttgaat catccctatt ctgtgtttta tctagtcaca 1250

 taaatggatt aattactaat ttcagttgag accttctaat tggtttttac 1300

 tgaaacattg agggaacaca aatttatggg cttcctgatg atgattcttc 1350

 taggcatcat gtcctatagt ttgtcatccc tgatgaatgt aaagttacac 1400

 tgttcacaaa ggttttgtct cctttccact gctattagtc atggtcactc 1450

 tccccaaaat attatatttt ttctataaaa aaaaaa 1486

<210> 2893
<211> 189
<212> PRT
<213> Homo sapien

<400> 2893
 Met Thr Glu Tyr Lys Leu Val Val Val Gly Ala Gly Gly Val Gly
   1               5                  10                  15

 Lys Ser Ala Leu Thr Ile Gln Leu Ile Gln Asn His Phe Val Asp
                  20                  25                  30

 Glu Tyr Asp Pro Thr Ile Glu Asp Ser Tyr Arg Lys Gln Val Val
                  35                  40                  45

 Ile Asp Gly Glu Thr Cys Leu Leu Asp Ile Leu Asp Thr Ala Gly
                  50                  55                  60

 Gln Glu Glu Tyr Ser Ala Met Arg Asp Gln Tyr Met Arg Thr Gly
                  65                  70                  75

 Glu Gly Phe Leu Cys Val Phe Ala Ile Asn Asn Thr Lys Ser Phe
                  80                  85                  90

 Glu Asp Ile His His Tyr Arg Glu Gln Ile Lys Arg Val Lys Asp
                  95                 100                 105

 Ser Glu Asp Val Pro Met Val Leu Val Gly Asn Lys Cys Asp Leu
                 110                 115                 120

 Pro Ser Arg Thr Val Asp Thr Lys Gln Ala Gln Asp Leu Ala Arg
                 125                 130                 135

 Ser Tyr Gly Ile Pro Phe Ile Glu Thr Ser Ala Lys Thr Arg Gln
                 140                 145                 150

 Arg Val Glu Asp Ala Phe Tyr Thr Leu Val Arg Glu Ile Arg Gln
                 155                 160                 165

 Tyr Arg Leu Lys Lys Ile Ser Lys Glu Glu Lys Thr Pro Gly Cys
                 170                 175                 180

 Val Lys Ile Lys Lys Cys Ile Ile Met
                 185

<210> 2894
<211> 2567
<212> DNA
<213> Homo sapien

<400> 2894
 ctccggcgca gtgttgggac tgtctgggta tcggaaagca agcctacgtt 50

 gctcactatt acgtataatc cttttctttt caagatgcct gaggaagtgc 100

 accatggaga ggaggaggtg gagacttttg cctttcaggc agaaattgcc 150

 caactcatgt ccctcatcat caataccttc tattccaaca aggagatttt 200

 ccttcgggag ttgatctcta atgcttctga tgccttggac aagattcgct 250

 atgagagcct gacagaccct tcgaagttgg acagtggtaa agagctgaaa 300

 attgacatca tccccaaccc tcaggaacgt accctgactt tggtagacac 350

 aggcattggc atgaccaaag ctgatctcat aaataatttg ggaaccattg 400

 ccaagtctgg tactaaagca ttcatggagg ctcttcaggc tggtgcagac 450

 atctccatga ttgggcagtt tggtgttggc ttttattctg cctacttggt 500

 ggcagagaaa gtggttgtga tcacaaagca caacgatgat gaacagtatg 550

 cttgggagtc ttctgctgga ggttccttca ctgtgcgtgc tgaccatggt 600

 gagcccattg gcaggggtac caaagtgatc ctccatctta aagaagatca 650

 gacagagtac ctagaagaga ggcgggtcaa agaagtagtg aagaagcatt 700

 ctcagttcat aggctatccc atcacccttt atttggagaa ggaacgagag 750

 aaggaaatta gtgatgatga ggcagaggaa gagaaaggtg agaaagaaga 800

 ggaagataaa gatgatgaag aaaaacccaa gatcgaagat gtgggttcag 850

 atgaggagga tgacagcggt aaggataaga agaagaaaac taagaagatc 900

 aaagagaaat acattgatca ggaagaacta aacaagacca agcctatttg 950

 gaccagaaac cctgatgaca tcacccaaga ggagtatgga gaattctaca 1000

 agagcctcac taatgactgg gaagaccact tggcagtcaa gcacttttct 1050

 gtagaaggtc agttggaatt cagggcattg ctatttattc ctcgtcgggc 1100

 tccctttgac ctttttgaga acaagaagaa aaagaacaac atcaaactct 1150

 atgtccgccg tgtgttcatc atggacagct gtgatgagtt gataccagag 1200

 tatctcaatt ttatccgtgg tgtggttgac tctgaggatc tgcccctgaa 1250

 catctcccga gaaatgctcc agcagagcaa aatcttgaaa gtcattcgca 1300

 aaaacattgt taagaagtgc cttgagctct tctctgagct ggcagaagac 1350

 aaggagaatt acaagaaatt ctatgaggca ttctctaaaa atctcaagct 1400

 tggaatccac gaagactcca ctaaccgccg ccgcctgtct gagctgctgc 1450

 gctatcatac ctcccagtct ggagatgaga tgacatctct gtcagagtat 1500

 gtttctcgca tgaaggagac acagaagtcc atctattaca tcactggtga 1550

 gagcaaagag caggtggcca actcagcttt tgtggagcga gtgcggaaac 1600

 ggggcttcga ggtggtatat atgaccgagc ccattgacga gtactgtgtg 1650

 cagcagctca aggaatttga tgggaagagc ctggtctcag ttaccaagga 1700

 gggtctggag ctgcctgagg atgaggagga gaagaagaag atggaagaga 1750

 gcaaggcaaa gtttgagaac ctctgcaagc tcatgaaaga aatcttagat 1800

 aagaaggttg agaaggtgac aatctccaat agacttgtgt cttcaccttg 1850

 ctgcattgtg accagcacct acggctggac agccaatatg gagcggatca 1900

 tgaaagccca ggcacttcgg gacaactcca ccatgggcta tatgatggcc 1950

 aaaaagcacc tggagatcaa ccctgaccac cccattgtgg agacgctgcg 2000

 gcagaaggct gaggccgaca agaatgataa ggcagttaag gacctggtgg 2050

 tgctgctgtt tgaaaccgcc ctgctatctt ctggcttttc ccttgaggat 2100

 ccccagaccc actccaaccg catctatcgc atgatcaagc taggtctagg 2150

 tattgatgaa gatgaagtgg cagcagagga acccaatgct gcagttcctg 2200

 atgagatccc ccctctcgag ggcgatgagg atgcgtctcg catggaagaa 2250

 gtcgattagg ttaggagttc atagttggaa aacttgtgcc cttgtatagt 2300

 gtccccatgg gctcccactg cagcctcgag tgcccctgtc ccacctggct 2350

 ccccctgctg gtgtctagtg tttttttccc tctcctgtcc ttgtgttgaa 2400

 ggcagtaaac taagggtgtc aagccccatt ccctctctac tcttgacagc 2450

 aggattggat gttgtgtatt gtggtttatt ttattttctt cattttgttc 2500

 tgaaattaaa gtatgcaaaa taaagaatat gccgttttaa aaaaaaaaaa 2550

 aaaaaaaaaa aaaaaaa 2567

<210> 2895
<211> 724
<212> PRT
<213> Homo sapien

<400> 2895
 Met Pro Glu Glu Val His His Gly Glu Glu Glu Val Glu Thr Phe
   1               5                  10                  15

 Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu Ile Ile Asn
                  20                  25                  30

 Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu Ile Ser
                  35                  40                  45

 Asn Ala Ser Asp Ala Leu Asp Lys Ile Arg Tyr Glu Ser Leu Thr
                  50                  55                  60

 Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu Lys Ile Asp Ile
                  65                  70                  75

 Ile Pro Asn Pro Gln Glu Arg Thr Leu Thr Leu Val Asp Thr Gly
                  80                  85                  90

 Ile Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile
                  95                 100                 105

 Ala Lys Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly
                 110                 115                 120

 Ala Asp Ile Ser Met Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser
                 125                 130                 135

 Ala Tyr Leu Val Ala Glu Lys Val Val Val Ile Thr Lys His Asn
                 140                 145                 150

 Asp Asp Glu Gln Tyr Ala Trp Glu Ser Ser Ala Gly Gly Ser Phe
                 155                 160                 165

 Thr Val Arg Ala Asp His Gly Glu Pro Ile Gly Arg Gly Thr Lys
                 170                 175                 180

 Val Ile Leu His Leu Lys Glu Asp Gln Thr Glu Tyr Leu Glu Glu
                 185                 190                 195

 Arg Arg Val Lys Glu Val Val Lys Lys His Ser Gln Phe Ile Gly
                 200                 205                 210

 Tyr Pro Ile Thr Leu Tyr Leu Glu Lys Glu Arg Glu Lys Glu Ile
                 215                 220                 225

 Ser Asp Asp Glu Ala Glu Glu Glu Lys Gly Glu Lys Glu Glu Glu
                 230                 235                 240

 Asp Lys Asp Asp Glu Glu Lys Pro Lys Ile Glu Asp Val Gly Ser
                 245                 250                 255

 Asp Glu Glu Asp Asp Ser Gly Lys Asp Lys Lys Lys Lys Thr Lys
                 260                 265                 270

 Lys Ile Lys Glu Lys Tyr Ile Asp Gln Glu Glu Leu Asn Lys Thr
                 275                 280                 285

 Lys Pro Ile Trp Thr Arg Asn Pro Asp Asp Ile Thr Gln Glu Glu
                 290                 295                 300

 Tyr Gly Glu Phe Tyr Lys Ser Leu Thr Asn Asp Trp Glu Asp His
                 305                 310                 315

 Leu Ala Val Lys His Phe Ser Val Glu Gly Gln Leu Glu Phe Arg
                 320                 325                 330

 Ala Leu Leu Phe Ile Pro Arg Arg Ala Pro Phe Asp Leu Phe Glu
                 335                 340                 345

 Asn Lys Lys Lys Lys Asn Asn Ile Lys Leu Tyr Val Arg Arg Val
                 350                 355                 360

 Phe Ile Met Asp Ser Cys Asp Glu Leu Ile Pro Glu Tyr Leu Asn
                 365                 370                 375

 Phe Ile Arg Gly Val Val Asp Ser Glu Asp Leu Pro Leu Asn Ile
                 380                 385                 390

 Ser Arg Glu Met Leu Gln Gln Ser Lys Ile Leu Lys Val Ile Arg
                 395                 400                 405

 Lys Asn Ile Val Lys Lys Cys Leu Glu Leu Phe Ser Glu Leu Ala
                 410                 415                 420

 Glu Asp Lys Glu Asn Tyr Lys Lys Phe Tyr Glu Ala Phe Ser Lys
                 425                 430                 435

 Asn Leu Lys Leu Gly Ile His Glu Asp Ser Thr Asn Arg Arg Arg
                 440                 445                 450

 Leu Ser Glu Leu Leu Arg Tyr His Thr Ser Gln Ser Gly Asp Glu
                 455                 460                 465

 Met Thr Ser Leu Ser Glu Tyr Val Ser Arg Met Lys Glu Thr Gln
                 470                 475                 480

 Lys Ser Ile Tyr Tyr Ile Thr Gly Glu Ser Lys Glu Gln Val Ala
                 485                 490                 495

 Asn Ser Ala Phe Val Glu Arg Val Arg Lys Arg Gly Phe Glu Val
                 500                 505                 510

 Val Tyr Met Thr Glu Pro Ile Asp Glu Tyr Cys Val Gln Gln Leu
                 515                 520                 525

 Lys Glu Phe Asp Gly Lys Ser Leu Val Ser Val Thr Lys Glu Gly
                 530                 535                 540

 Leu Glu Leu Pro Glu Asp Glu Glu Glu Lys Lys Lys Met Glu Glu
                 545                 550                 555

 Ser Lys Ala Lys Phe Glu Asn Leu Cys Lys Leu Met Lys Glu Ile
                 560                 565                 570

 Leu Asp Lys Lys Val Glu Lys Val Thr Ile Ser Asn Arg Leu Val
                 575                 580                 585

 Ser Ser Pro Cys Cys Ile Val Thr Ser Thr Tyr Gly Trp Thr Ala
                 590                 595                 600

 Asn Met Glu Arg Ile Met Lys Ala Gln Ala Leu Arg Asp Asn Ser
                 605                 610                 615

 Thr Met Gly Tyr Met Met Ala Lys Lys His Leu Glu Ile Asn Pro
                 620                 625                 630

 Asp His Pro Ile Val Glu Thr Leu Arg Gln Lys Ala Glu Ala Asp
                 635                 640                 645

 Lys Asn Asp Lys Ala Val Lys Asp Leu Val Val Leu Leu Phe Glu
                 650                 655                 660

 Thr Ala Leu Leu Ser Ser Gly Phe Ser Leu Glu Asp Pro Gln Thr
                 665                 670                 675

 His Ser Asn Arg Ile Tyr Arg Met Ile Lys Leu Gly Leu Gly Ile
                 680                 685                 690

 Asp Glu Asp Glu Val Ala Ala Glu Glu Pro Asn Ala Ala Val Pro
                 695                 700                 705

 Asp Glu Ile Pro Pro Leu Glu Gly Asp Glu Asp Ala Ser Arg Met
                 710                 715                 720

 Glu Glu Val Asp


<210> 2896
<211> 1155
<212> DNA
<213> Homo sapien

<400> 2896
 atggattgca gtaacggatc ggcagagtgt accggagaag gaggatcaaa 50

 agaggtggtg gggactttta aggctaaaga cctaatagtc acaccagcta 100

 ccattttaaa ggaaaaacca gaccccaata atctggtttt tggaactgtg 150

 ttcacggatc atatgctgac ggtggagtgg tcctcagagt ttggatggga 200

 gaaacctcat atcaagcctc ttcagaacct gtcattgcac cctggctcat 250

 cagctttgca ctatgcagtg gaattatttg aaggattgaa ggcatttcga 300

 ggagtagata ataaaattcg actgtttcag ccaaacctca acatggatag 350

 aatgtatcgc tctgctgtga gggcaactct gccggtattt gacaaagaag 400

 agctcttaga gtgtattcaa cagcttgtga aattggatca agaatgggtc 450

 ccatattcaa catctgctag tctgtatatt cgtcctgcat tcattggaac 500

 tgagccttct cttggagtca agaagcctac caaagccctg ctctttgtac 550

 tcttgagccc agtgggacct tatttttcaa gtggaacctt taatccagtg 600

 tccctgtggg ccaatcccaa gtatgtaaga gcctggaaag gtggaactgg 650

 ggactgcaag atgggaggga attacggctc atctcttttt gcccaatgtg 700

 aagacgtaga taatgggtgt cagcaggtcc tgtggctcta tggcagagac 750

 catcagatca ctgaagtggg aactatgaat ctttttcttt actggataaa 800

 tgaagatgga gaagaagaac tggcaactcc tccactagat ggcatcattc 850

 ttccaggagt gacaaggcgg tgcattctgg acctggcaca tcagtggggt 900

 gaatttaagg tgtcagagag atacctcacc atggatgact tgacaacagc 950

 cctggagggg aacagagtga gagagatgtt tagctctggt acagcctgtg 1000

 ttgtttgccc agtttctgat atactgtaca aaggcgagac aatacacatt 1050

 ccaactatgg agaatggtcc taagctggca agccgcatct tgagcaaatt 1100

 aactgatatc cagtatggaa gagaagagag cgactggaca attgtgctat 1150

 cctga 1155

<210> 2897
<211> 384
<212> PRT
<213> Homo sapien

<400> 2897
 Met Asp Cys Ser Asn Gly Ser Ala Glu Cys Thr Gly Glu Gly Gly
   1               5                  10                  15

 Ser Lys Glu Val Val Gly Thr Phe Lys Ala Lys Asp Leu Ile Val
                  20                  25                  30

 Thr Pro Ala Thr Ile Leu Lys Glu Lys Pro Asp Pro Asn Asn Leu
                  35                  40                  45

 Val Phe Gly Thr Val Phe Thr Asp His Met Leu Thr Val Glu Trp
                  50                  55                  60

 Ser Ser Glu Phe Gly Trp Glu Lys Pro His Ile Lys Pro Leu Gln
                  65                  70                  75

 Asn Leu Ser Leu His Pro Gly Ser Ser Ala Leu His Tyr Ala Val
                  80                  85                  90

 Glu Leu Phe Glu Gly Leu Lys Ala Phe Arg Gly Val Asp Asn Lys
                  95                 100                 105

 Ile Arg Leu Phe Gln Pro Asn Leu Asn Met Asp Arg Met Tyr Arg
                 110                 115                 120

 Ser Ala Val Arg Ala Thr Leu Pro Val Phe Asp Lys Glu Glu Leu
                 125                 130                 135

 Leu Glu Cys Ile Gln Gln Leu Val Lys Leu Asp Gln Glu Trp Val
                 140                 145                 150

 Pro Tyr Ser Thr Ser Ala Ser Leu Tyr Ile Arg Pro Ala Phe Ile
                 155                 160                 165

 Gly Thr Glu Pro Ser Leu Gly Val Lys Lys Pro Thr Lys Ala Leu
                 170                 175                 180

 Leu Phe Val Leu Leu Ser Pro Val Gly Pro Tyr Phe Ser Ser Gly
                 185                 190                 195

 Thr Phe Asn Pro Val Ser Leu Trp Ala Asn Pro Lys Tyr Val Arg
                 200                 205                 210

 Ala Trp Lys Gly Gly Thr Gly Asp Cys Lys Met Gly Gly Asn Tyr
                 215                 220                 225

 Gly Ser Ser Leu Phe Ala Gln Cys Glu Asp Val Asp Asn Gly Cys
                 230                 235                 240

 Gln Gln Val Leu Trp Leu Tyr Gly Arg Asp His Gln Ile Thr Glu
                 245                 250                 255

 Val Gly Thr Met Asn Leu Phe Leu Tyr Trp Ile Asn Glu Asp Gly
                 260                 265                 270

 Glu Glu Glu Leu Ala Thr Pro Pro Leu Asp Gly Ile Ile Leu Pro
                 275                 280                 285

 Gly Val Thr Arg Arg Cys Ile Leu Asp Leu Ala His Gln Trp Gly
                 290                 295                 300

 Glu Phe Lys Val Ser Glu Arg Tyr Leu Thr Met Asp Asp Leu Thr
                 305                 310                 315

 Thr Ala Leu Glu Gly Asn Arg Val Arg Glu Met Phe Ser Ser Gly
                 320                 325                 330

 Thr Ala Cys Val Val Cys Pro Val Ser Asp Ile Leu Tyr Lys Gly
                 335                 340                 345

 Glu Thr Ile His Ile Pro Thr Met Glu Asn Gly Pro Lys Leu Ala
                 350                 355                 360

 Ser Arg Ile Leu Ser Lys Leu Thr Asp Ile Gln Tyr Gly Arg Glu
                 365                 370                 375

 Glu Ser Asp Trp Thr Ile Val Leu Ser
                 380

<210> 2898
<211> 3019
<212> DNA
<213> Homo sapien

<400> 2898
 gcaaccagta ctacccgaga gccttgggcc tcgggggaga tgtcaggtgg 50

 gtgcatgggg cctgggtccc ggtccctgct gtgctcctca ctgtttgact 100

 gaccttgatg ggatcctgaa cgtctcagag gctgctcccc tgtgacatgg 150

 accctggcga cctgtacacc agcgtcacca gggttgttct gcaggtcaaa 200

 agagacaatg tgggtgaagc agtcccctgg cgtcaggtac cttttgtcgg 250

 aactgctggg agctctatgg cccaggccca ccccagctta cttgctgacc 300

 ttggcctcgc ctttcctgac tttcagtctc cctataaaat tggagatccc 350

 acagagatct cagacccccc tgcagcccct ggtcagccca ggggaacaga 400

 ccccatgttt ctttccagca acactgccca ctcagcgagg aagcagccgc 450

 gacgcccaca cttcctgttg gagcctgcgc agagccagag gtccctgggg 500

 tgcagcaccg tgggcaggca gggggagatg gtcaggggtc cccagaggca 550

 gcgggcacct ccatgtgggg cctgtgtttt ggcagccctg gggtgggtgg 600

 ccccctttcc ttcttgttct ttggtcccag aggagggtcc tgtggcctga 650

 ccaggctctt gccttccctg tgctcaggcc tcagaagcca caggaacatg 700

 gcctaggcat ggctcagcca gcagccccct ccctgacgcg gcccttcctg 750

 gcagaggccc cgacagcact ggtcccacac agccccctgc ctggggccct 800

 gtcaagcgcc cctggcccga agcagccccc gacggcaagc acaggcccgg 850

 agctgctgct gctgcctctt tcctccttca tgccctgcgg ggcggctgca 900

 ccagccaggg tacgtcctcc accaccaggc ctgggcactg gggctctcac 950

 tctggtctga cttctggtgc tttctcatgc cacagctgta ctagtttctg 1000

 gaaaaccttg gcacagggag gccactcatc catttgacaa gcataggtag 1050

 ccactgcaca ccaggtccaa gggccacagc agtgaacagc cagccaaggg 1100

 ccctgccatc ctgaagctta tattctagtc agagacaagc aaagaaaaac 1150

 ccctgcctgc aggccagtaa agtggctgca gatcacgtag ggtcctgcag 1200

 gccacagtga gaagtagcct gggatttgag aagagtagga agtcggggaa 1250

 gggttttggc agggagcacc atgtcaggtt tctgtgcagg ctgtggtcac 1300

 catgaccacg tggtccaggc aagtagtact ggtggcctgg gctcagcggt 1350

 tgccacagag gggacaggta ctctcttgga ggcagatgag gcaggatatg 1400

 ctgctctgag ggagttgctg aatgagggga aagaaggaat ccaggctgat 1450

 gtgggctgct ggcttgaata acttgggaaa cagagttctt tgactggaag 1500

 aaggaactgg gggtggggac tggtttgggg tgaagtgtca agagtgtttt 1550

 gaaccaggct cttgatgtca aacttgagag aaagcaaacg ttgagtctga 1600

 ccttcaagga agaggtcagg gccagagatt gagaagaatc ttcagcacag 1650

 gccgaaggta accccagagc cactgcggcc tctaggagga gagtacaggg 1700

 gaaggagaga ggggaggagg ctccaagcag ggagcctggg tggggatggc 1750

 cagggggtgt gagagctcag taatggaagt gacagctgct ctaaggccac 1800

 caaagcagct ggttcctgaa aggggatgag gggacaggaa ggaaccagtt 1850

 cctgtggtga gttaggccat gtggggccac ttaccctggc tggaatggtt 1900

 tgaatgtggg tttgaaaggg ttttgacccc tgtccggtga tggaaggggc 1950

 aagtccactc tcaccaggag aggagggcat ggaaaaggct gtagagcagt 2000

 ggcctctcac tgaccacttc tcactgatgt caaagctcag caaggtcatg 2050

 agcttagagc aggtgggggt ggagggttgg gtaaggcaag gctaggaaca 2100

 gctgctcagg cagtggaggc gtgaggcgga ctgtggtgac acggggtgct 2150

 ccctggttgc ttgcgggact ttcccctaca gtaccaggcc ctgtgtgcag 2200

 gggcaggcta gacactgagc tggcacggcc agtgcctggg aagcccagct 2250

 cctgcagctg ggagcctggt cttcccccac ccctacaggg caggcagtga 2300

 caaggacttg gtgtccccct ccctggcttc ctcctagctt ccttgctcag 2350

 catctaccct tctttccttt gcaggtgtca gcacagcggg ctactcctag 2400

 ggataagccc ccggtcccct catccctggc cagtgtccct gacccccatc 2450

 tactccttcc tggggacttc tcagccacca gggctgggcc tggactttca 2500

 actgcaggca gcctggacct tgaggctgaa cttgagaaga tccagcagca 2550

 actactgcac taccagacca ccaagcagaa cctctggtcc tgtcggcggc 2600

 aagcgagcag cctgcgcagg tggctggagc tgaacagaga ggagccgggg 2650

 cctgaggacc aggaagtaga gcagcaggtg cagaaagagc tggaacaggt 2700

 gaggccccag gccatcccca ggtgtccctg gggacgcccc gggctgtgct 2750

 ccctctcagc cctgcctgtc cctccatggc cccaggtgga aatgcagatc 2800

 cagctgctgg cagaggagct ccaggctcag cgccagccca ttggcgcctg 2850

 cgttgcccgc atccaggccc tgcggcaggc cctgtgctag cgtgttcgca 2900

 ccaggaacgc aggtgctggg ctgtcgggga ggcctcaggc cacctccagg 2950

 aacagaacac agttttaagt ttgatttttt ttatttcaaa atgctttgca 3000

 attaaatgaa ttactgttc 3019

<210> 2899
<211> 250
<212> PRT
<213> Homo sapien

<400> 2899
 Met Trp Val Lys Gln Ser Pro Gly Val Arg Tyr Leu Leu Ser Glu
   1               5                  10                  15

 Leu Leu Gly Ala Leu Trp Pro Arg Pro Thr Pro Ala Tyr Leu Leu
                  20                  25                  30

 Thr Leu Ala Ser Pro Phe Leu Thr Phe Ser Leu Pro Ile Lys Leu
                  35                  40                  45

 Glu Ile Pro Gln Arg Ser Gln Thr Pro Leu Gln Pro Leu Val Ser
                  50                  55                  60

 Pro Gly Glu Gln Thr Pro Cys Phe Phe Pro Ala Thr Leu Pro Thr
                  65                  70                  75

 Gln Arg Gly Ser Ser Arg Asp Ala His Thr Ser Cys Trp Ser Leu
                  80                  85                  90

 Arg Arg Ala Arg Gly Pro Trp Gly Ala Ala Pro Trp Ala Gly Arg
                  95                 100                 105

 Gly Arg Trp Ser Gly Val Pro Arg Gly Ser Gly His Leu His Val
                 110                 115                 120

 Gly Pro Val Phe Trp Gln Pro Trp Gly Gly Trp Pro Pro Phe Leu
                 125                 130                 135

 Leu Val Leu Trp Ser Gln Arg Arg Val Leu Trp Pro Asp Gln Ala
                 140                 145                 150

 Leu Ala Phe Pro Val Leu Arg Pro Gln Lys Pro Gln Glu His Gly
                 155                 160                 165

 Leu Gly Met Ala Gln Pro Ala Ala Pro Ser Leu Thr Arg Pro Phe
                 170                 175                 180

 Leu Ala Glu Ala Pro Thr Ala Leu Val Pro His Ser Pro Leu Pro
                 185                 190                 195

 Gly Ala Leu Ser Ser Ala Pro Gly Pro Lys Gln Pro Pro Thr Ala
                 200                 205                 210

 Ser Thr Gly Pro Glu Leu Leu Leu Leu Pro Leu Ser Ser Phe Met
                 215                 220                 225

 Pro Cys Gly Ala Ala Ala Pro Ala Arg Val Arg Pro Pro Pro Pro
                 230                 235                 240

 Gly Leu Gly Thr Gly Ala Leu Thr Leu Val
                 245                 250

<210> 2900
<211> 1350
<212> DNA
<213> Homo sapien

<400> 2900
 aggttaatct taaaagccca ggttacccgc ggaaatttat gctgtccggt 50

 caccgtgaca atgcagctga ggaacccaga actacatctg ggctgcgcgc 100

 ttgcgcttcg cttcctggcc ctcgtttcct gggacatccc tggggctaga 150

 gcactggaca atggattggc aaggacgcct accatgggct ggctgcactg 200

 ggagcgcttc atgtgcaacc ttgactgcca ggaagagcca gattcctgca 250

 tcagtgagaa gctcttcatg gagatggcag agctcatggt ctcagaaggc 300

 tggaaggatg caggttatga gtacctctgc attgatgact gttggatggc 350

 tccccaaaga gattcagaag gcagacttca ggcagaccct cagcgctttc 400

 ctcatgggat tcgccagcta gctaattatg ttcacagcaa aggactgaag 450

 ctagggattt atgcagatgt tggaaataaa acctgcgcag gcttccctgg 500

 gagttttgga tactacgaca ttgatgccca gacctttgct gactggggag 550

 tagatctgct aaaatttgat ggttgttact gtgacagttt ggaaaatttg 600

 gcagatggtt ataagcacat gtccttggcc ctgaatagga ctggcagaag 650

 cattgtgtac tcctgtgagt ggcctcttta tatgtggccc tttcaaaagc 700

 ccaattatac agaaatccga cagtactgca atcactggcg aaattttgct 750

 gacattgatg attcctggaa aagtataaag agtatcttgg actggacatc 800

 ttttaaccag gagagaattg ttgatgttgc tggaccaggg ggttggaatg 850

 acccagatat gttagtgatt ggcaactttg gcctcagctg gaatcagcaa 900

 gtaactcaga tggccctctg ggctatcatg gctgctcctt tattcatgtc 950

 taatgacctc cgacacatca gccctcaagc caaagctctc cttcaggata 1000

 aggacgtaat tgccatcaat caggacccct tgggcaagca agggtaccag 1050

 cttagacagg gagacaactt tgaagtgtgg gaacgacctc tctcaggctt 1100

 agcctgggct gtagctatga taaaccggca ggagattggt ggacctcgct 1150

 cttataccat cgcagttgct tccctgggta aaggagtggc ctgtaatcct 1200

 gcctgcttca tcacacagct cctccctgtg aaaaggaagc tagggttcta 1250

 tgaatggact tcaaggttaa gaagtcacat aaatcccaca ggcactgttt 1300

 tgcttcagct agaaaataca atgcagatgt cattaaaaga cttactttaa 1350

<210> 2901
<211> 429
<212> PRT
<213> Homo sapien

<400> 2901
 Met Gln Leu Arg Asn Pro Glu Leu His Leu Gly Cys Ala Leu Ala
   1               5                  10                  15

 Leu Arg Phe Leu Ala Leu Val Ser Trp Asp Ile Pro Gly Ala Arg
                  20                  25                  30

 Ala Leu Asp Asn Gly Leu Ala Arg Thr Pro Thr Met Gly Trp Leu
                  35                  40                  45

 His Trp Glu Arg Phe Met Cys Asn Leu Asp Cys Gln Glu Glu Pro
                  50                  55                  60

 Asp Ser Cys Ile Ser Glu Lys Leu Phe Met Glu Met Ala Glu Leu
                  65                  70                  75

 Met Val Ser Glu Gly Trp Lys Asp Ala Gly Tyr Glu Tyr Leu Cys
                  80                  85                  90

 Ile Asp Asp Cys Trp Met Ala Pro Gln Arg Asp Ser Glu Gly Arg
                  95                 100                 105

 Leu Gln Ala Asp Pro Gln Arg Phe Pro His Gly Ile Arg Gln Leu
                 110                 115                 120

 Ala Asn Tyr Val His Ser Lys Gly Leu Lys Leu Gly Ile Tyr Ala
                 125                 130                 135

 Asp Val Gly Asn Lys Thr Cys Ala Gly Phe Pro Gly Ser Phe Gly
                 140                 145                 150

 Tyr Tyr Asp Ile Asp Ala Gln Thr Phe Ala Asp Trp Gly Val Asp
                 155                 160                 165

 Leu Leu Lys Phe Asp Gly Cys Tyr Cys Asp Ser Leu Glu Asn Leu
                 170                 175                 180

 Ala Asp Gly Tyr Lys His Met Ser Leu Ala Leu Asn Arg Thr Gly
                 185                 190                 195

 Arg Ser Ile Val Tyr Ser Cys Glu Trp Pro Leu Tyr Met Trp Pro
                 200                 205                 210

 Phe Gln Lys Pro Asn Tyr Thr Glu Ile Arg Gln Tyr Cys Asn His
                 215                 220                 225

 Trp Arg Asn Phe Ala Asp Ile Asp Asp Ser Trp Lys Ser Ile Lys
                 230                 235                 240

 Ser Ile Leu Asp Trp Thr Ser Phe Asn Gln Glu Arg Ile Val Asp
                 245                 250                 255

 Val Ala Gly Pro Gly Gly Trp Asn Asp Pro Asp Met Leu Val Ile
                 260                 265                 270

 Gly Asn Phe Gly Leu Ser Trp Asn Gln Gln Val Thr Gln Met Ala
                 275                 280                 285

 Leu Trp Ala Ile Met Ala Ala Pro Leu Phe Met Ser Asn Asp Leu
                 290                 295                 300

 Arg His Ile Ser Pro Gln Ala Lys Ala Leu Leu Gln Asp Lys Asp
                 305                 310                 315

 Val Ile Ala Ile Asn Gln Asp Pro Leu Gly Lys Gln Gly Tyr Gln
                 320                 325                 330

 Leu Arg Gln Gly Asp Asn Phe Glu Val Trp Glu Arg Pro Leu Ser
                 335                 340                 345

 Gly Leu Ala Trp Ala Val Ala Met Ile Asn Arg Gln Glu Ile Gly
                 350                 355                 360

 Gly Pro Arg Ser Tyr Thr Ile Ala Val Ala Ser Leu Gly Lys Gly
                 365                 370                 375

 Val Ala Cys Asn Pro Ala Cys Phe Ile Thr Gln Leu Leu Pro Val
                 380                 385                 390

 Lys Arg Lys Leu Gly Phe Tyr Glu Trp Thr Ser Arg Leu Arg Ser
                 395                 400                 405

 His Ile Asn Pro Thr Gly Thr Val Leu Leu Gln Leu Glu Asn Thr
                 410                 415                 420

 Met Gln Met Ser Leu Lys Asp Leu Leu
                 425

<210> 2902
<211> 2774
<212> DNA
<213> Homo sapien

<400> 2902
 ccgctcccca gagcaaagcg tcggagtcct cctcctcctt ctcctcctcc 50

 tcctcctcct cctccagccg cccaggctcc cccgccaccc gtcagactcc 100

 tccttcgacc gctcccggcg cggggccttc caggcgacaa ggaccgagta 150

 ccctccggcc ggagccacgc agccgcggct tccggagccc tcggggcggc 200

 ggactggctc gcggtgcaga ttcttcttaa tcctttggtg aaaactgaga 250

 cacaaaatgg ctgcaaataa gcccaagggt cagaattctt tggctttaca 300

 caaagtcatc atggtgggca gtggtggcgt gggcaagtca gctctgactc 350

 tacagttcat gtacgatgag tttgtggagg actatgagcc taccaaagca 400

 gacagctatc ggaagaaggt agtgctagat ggggaggaag tccagatcga 450

 tatcttagat acagctgggc aggaggacta cgctgcaatt agagacaact 500

 acttccgaag tggggagggg ttcctctgtg ttttctctat tacagaaatg 550

 gaatcctttg cagctacagc tgacttcagg gagcagattt taagagtaaa 600

 agaagatgag aatgttccat ttctactggt tggtaacaaa tcagatttag 650

 aagataaaag acaggtttct gtagaagagg caaaaaacag agctgagcag 700

 tggaatgtta actacgtgga aacatctgct aaaacacgag ctaatgttga 750

 caaggtattt tttgatttaa tgagagaaat tcgagcgaga aagatggaag 800

 acagcaaaga aaagaatgga aaaaagaaga ggaaaagttt agccaagaga 850

 atcagagaaa gatgctgcat tttataatca aagcccaaac tcctttctta 900

 tcttgaccat actaataaat ataatttata agcattgcca ttgaaggctt 950

 aattgactga aattacttta acattttgga aattgttgta tatcactaaa 1000

 agcatgaatt ggaactgcaa tgaaagtcaa atttacttta aaaagaaatt 1050

 aatatggctt caccaagaag caaagttcaa cttatttcat aattgcctac 1100

 atttatcatg gtcctgaatg tagcgtgtaa gcttgtgttt cttgggcagt 1150

 ctttcttgaa attgaagagg tgaaatgggg gtggggagtg ggaggaaagg 1200

 tgacttcctc tggtgtttat tataaagctt aaattttata tcattttaaa 1250

 atgtcttggt cttctactgc cttgaaaaat gacaattgtg aacatgatag 1300

 ttaaactacc acttttttta accattatta tgcaaaattt agaagaaaag 1350

 ttattggcat ggttgttgca tatagttaaa ctgagagtaa ttcatctgtg 1400

 aatctgcttt aattacctgg tgagtaactt agaaaagtgg tgtaaacttg 1450

 tacatggaat tttttgaata tgccttaatt tagaaactga aaaatatctg 1500

 gttatatcat tctgggtgtg ttcttactga caccaggggt ccgctgcccc 1550

 atgtgtcctg gtgagaaaat atatgcctgg cacagctttt gtatagaaaa 1600

 ttcttgagaa gtaactgtcc gctagaagtc tgtccaaatt taaaatgtgt 1650

 gccatattct ggttcttgaa aataagattc cagagctctt tgatcgcttt 1700

 taataaactg caagttcatt ttaaatgaag ggccagcata tatacttgca 1750

 agataatttt cagctgcaag gattcagcac cagttatgtt tgaatgaacc 1800

 ctccttttct ctgagattct ggtccctgga aatccctttc tgctagtggt 1850

 gagcatgtaa gtgttaagtt tttaatctgg gagcagggca taggaagaaa 1900

 atgtcagtag tgctaatgca ttttgcacta gaacgcttcg ggaaaatatt 1950

 catgcttgcc atctgttcat ttctaaattt atattcataa agttacagtt 2000

 tgatacagga attattagga gtaattcttt tctgtttctg tttataatga 2050

 agaacactgt agctacattt tcagaagtta acatcaagcc atcaaacctg 2100

 ggtatagtgc agaaaacgtg gcacacactg accacacatt aggctgtgtc 2150

 accattgtgt ggtgtacctg ctggaagaat tctagcatgc tacttgggga 2200

 cataatttca gtgggaaata tgccactgac cgattttttt tttttcctct 2250

 ttgcagtggg gctaggacag ttgattcaac aaagtatttt tttctttttt 2300

 ctcagtccta atttgaacag gtcaaagatg tgttcaggca ttccaggtaa 2350

 caggtgtgta tgtaaagtta aaaataggct ttttaggaac tcactcttta 2400

 gatatttaca tccagcttct catgttaaat atttgtcctt aaagggtttg 2450

 agatgtacat ctttcatttc gtatttctca taggctatgc catgtgcgga 2500

 attcaagtta ccaatgtaac actggccagc gggcccagca atctccatgt 2550

 gtacttatta cagtcttatt taaccagggg tcctaaccac taacattgtg 2600

 actttgcttt gagacctttc ctctcctggg tactgaggtg ctatgaagcc 2650

 aactgacaaa gatgcatcac gtgtcttagg ctgatgccac tacccgattt 2700

 gtttatttgc aatttgagcc atttaaagac caataaactt ccttttttaa 2750

 aaaaaaaaaa aaaaaaaaaa aaaa 2774

<210> 2903
<211> 206
<212> PRT
<213> Homo sapien

<400> 2903
 Met Ala Ala Asn Lys Pro Lys Gly Gln Asn Ser Leu Ala Leu His
   1               5                  10                  15

 Lys Val Ile Met Val Gly Ser Gly Gly Val Gly Lys Ser Ala Leu
                  20                  25                  30

 Thr Leu Gln Phe Met Tyr Asp Glu Phe Val Glu Asp Tyr Glu Pro
                  35                  40                  45

 Thr Lys Ala Asp Ser Tyr Arg Lys Lys Val Val Leu Asp Gly Glu
                  50                  55                  60

 Glu Val Gln Ile Asp Ile Leu Asp Thr Ala Gly Gln Glu Asp Tyr
                  65                  70                  75

 Ala Ala Ile Arg Asp Asn Tyr Phe Arg Ser Gly Glu Gly Phe Leu
                  80                  85                  90

 Cys Val Phe Ser Ile Thr Glu Met Glu Ser Phe Ala Ala Thr Ala
                  95                 100                 105

 Asp Phe Arg Glu Gln Ile Leu Arg Val Lys Glu Asp Glu Asn Val
                 110                 115                 120

 Pro Phe Leu Leu Val Gly Asn Lys Ser Asp Leu Glu Asp Lys Arg
                 125                 130                 135

 Gln Val Ser Val Glu Glu Ala Lys Asn Arg Ala Glu Gln Trp Asn
                 140                 145                 150

 Val Asn Tyr Val Glu Thr Ser Ala Lys Thr Arg Ala Asn Val Asp
                 155                 160                 165

 Lys Val Phe Phe Asp Leu Met Arg Glu Ile Arg Ala Arg Lys Met
                 170                 175                 180

 Glu Asp Ser Lys Glu Lys Asn Gly Lys Lys Lys Arg Lys Ser Leu
                 185                 190                 195

 Ala Lys Arg Ile Arg Glu Arg Cys Cys Ile Leu
                 200                 205

<210> 2904
<211> 3772
<212> DNA
<213> Homo sapien

<400> 2904
 agcgggataa gttggcgcgt cacctagacg tcagcctctt acctctcgga 50

 cgtcccgtcc caggagcaaa actctagtga ctttgggccc gcccccgtga 100

 gagtggaggg cggccgatga gggcggttct gaagggaaca agaccaatga 150

 gacgagcccg gggcggggcg cggggccgga gggtggggcg ggtggcggcg 200

 gtggcagtcc gaggtctggc tccgcgcagt atatgacagt acgtcagcag 250

 cgggatggcc ctagcagtgg cggcggctgc agaagcccaa gcagccgcgg 300

 ccgcagtgga ggctagagcc ggagcggcgg cggcggcggc accccgggga 350

 gtttaagatg gcggcggggg ggacaggggg cctgcgggag gagcagcgct 400

 atgggctgtc gtgcggacgg ctggggcagg acaacatcac cgtactgcat 450

 gtgaagctca ccgagacggc gatccgggcg ctcgagactt accagagcca 500

 caagaattta attccttttc gaccttcaat ccagttccaa ggactccacg 550

 ggcttgtcaa aattcccaaa aatgatcccc tcaatgaagt tcataacttt 600

 aacttttatt tgtcaaatgt gggcaaagac aaccctcagg gcagctttga 650

 ctgcatccag caaacattct ccagctctgg agcctcccag ctcaattgcc 700

 tgggatttat acaagataaa attacagtgt gtgcaacaaa cgactcgtat 750

 cagatgacac gagaaagaat gacccaggca gaggaggaat cccgcaaccg 800

 aagcacaaaa gttatcaaac ccggtggacc atatgtaggg aaaagagtgc 850

 aaattcggaa agcacctcaa gctgtttcag atacagttcc tgagaggaaa 900

 aggtcaaccc ccatgaaccc tgcaaataca attcgaaaga cacatagcag 950

 cagcaccatc tctcagaggc catacaggga cagggtgatt cacttactgg 1000

 ccctgaaggc ctacaagaaa ccggagctac ttgctagact ccagaaagat 1050

 ggtgtcaatc aaaaagacaa gaactccctg ggagcaattc tgcaacaggt 1100

 agccaatctg aattctaagg acctctcata taccttaaag gattatgttt 1150

 ttaaagagct tcaaagagac tggcctggat acagtgaaat agacagacgg 1200

 tcattggagt cagtgctctc tagaaaacta aatccgtctc agaatgctac 1250

 aggcaccagc cgttcagaat ctcctgtatg ttctagtaga gatgctgtat 1300

 cttctcctca gaaacggctt ttggattcag agtttattga tcctttaatg 1350

 aataaaaaag cccgaatatc tcacctgacg aacagagtac caccaacact 1400

 aaatggtcat ttgaatccca ccagtgaaaa atcggctgca ggcctcccac 1450

 tgccccctgc ggctgctgcc atccccaccc ctccaccgct gccttcaacc 1500

 tatctgccca tctcacatcc tcctcagatt gtaaattcta actccaactc 1550

 ccctagcact ccagaaggcc gggggactca agacctacct gttgacagtt 1600

 ttagtcaaaa cgatagtatc tatgaggacc agcaagacaa atatacctct 1650

 aggacttctc tggaaacctt accccctggt tccgttctac taaagtgtcc 1700

 aaagcctatg gaagaaaacc attcaatgtc tcacaaaaag tccaaaaaga 1750

 agtctaaaaa acataaggaa aaggaccaaa taaaaaagca cgacattgag 1800

 actattgagg aaaaggagga agatcttaag agagaagagg aaattgccaa 1850

 gctaaataac tccagtccaa attccagtgg aggagttaaa gaggattgca 1900

 ctgcctccat ggaaccttca gcaattgaac tcccagatta tttgataaaa 1950

 tatatcgcta tcgtctccta tgagcaacgc cagaattata aggatgactt 2000

 caatgcagag tatgatgagt acagagcttt gcatgccagg atggagactg 2050

 tagctagaag atttatcaaa ctagatgcac aaagaaagcg cctttctcca 2100

 ggctcaaaag agtatcagaa tgttcatgaa gaagtcttac aagaatatca 2150

 gaagataaag cagtctagtc ccaattacca tgaagaaaaa tacagatgtg 2200

 aatatcttca taacaagctg gctcacatca aaaggctaat aggtgaattt 2250

 gaccaacagc aagcagagtc atggtcctag aactctgctt ggaccagaag 2300

 atgtgaataa acttaagctt atttatttaa aattccaaat gagttgctct 2350

 agattctaaa aaggtgaaac tttggctgtt gaaagtttca gtattagtaa 2400

 acttgagtta ctttttcttt tccattttac tttgcttccc tgcatttcga 2450

 agctgctctt tctggtcctc cccaccaccc cacccccaag acttgtgttt 2500

 gttaatagaa ataatttttt taggtattgg ggatccattg tctatatttc 2550

 aaatcagttt tttttcctca aaaacttgtg tttgttatta gaaatgattt 2600

 tttagatatt ggggatccag tgtccacact taaaagttgt atgtgtttaa 2650

 aaaacaacaa cagtaatgtg caaggtgaaa tgcttttgga taaacgtaag 2700

 cctattttct gacgtttctt aatgcaaact ctttgcctta aatggtagaa 2750

 tatttagaaa tttgcacaaa attaaaaaaa taaacattgt cttggagggt 2800

 taaaaaatag aaaggtgtat gtgtatagat tcacatacac atatgtatat 2850

 acaggctgac ttgatctaga acattaaatc cgccctgcaa gttaaccccc 2900

 cattgcaatg gttgccttaa ggtgtttgct agttgtgtac atagtgtggt 2950

 taatcattag ctacactgct tcccacttga ttagagcaat gggaagcata 3000

 ctgtggccta ccagcatctg gaagtgtgtg ctcgatctgt atgtgtgcag 3050

 aggtggtgtg gatgtgagcg tgcatgaagg aaaaaaagct gctactccta 3100

 gtaggccaaa cgctcaggtt aaacaactga cgagtgttac tgtagggtgt 3150

 ttttttgttt ttttgttttt tttcttctat caaattgcta cttttgttgt 3200

 ggaagacaaa agcatttcca tttcaacgag tttgtcagct ttattaatgt 3250

 tgggcaaaaa ttgatatgtc atgaaaatga aacagatcta tagttttggg 3300

 acaaaattat aaaatgaaat gtgtaggtaa cctatttata tactgctata 3350

 aagtattttt tgaagagaga tatgcaaaga agctattacc tacataagag 3400

 gtatatttaa agattttttt tttttcatcc tggtgccagg aatataaaaa 3450

 agagtggata tatttaacca taacatactg tgattcatca aacagcacaa 3500

 actttcattt catggagttt atctgttgac attgatttaa actgtcactt 3550

 gttttatcat gtgggaacat aagttatgtg gtcaaaaata taaggatttt 3600

 gaattaatgt tgattcaagt tgtattgtct tattgtattg tcttttcaaa 3650

 gtgctgccag ttgaaaaggg aagcattatg tttacaaatc tgttttgaaa 3700

 tgtttgccaa aattttggta gtgtctttaa taaagatgtt tgtctccagc 3750

 atccagaaaa aaaaaaaaaa aa 3772

<210> 2905
<211> 640
<212> PRT
<213> Homo sapien

<400> 2905
 Met Ala Ala Gly Gly Thr Gly Gly Leu Arg Glu Glu Gln Arg Tyr
   1               5                  10                  15

 Gly Leu Ser Cys Gly Arg Leu Gly Gln Asp Asn Ile Thr Val Leu
                  20                  25                  30

 His Val Lys Leu Thr Glu Thr Ala Ile Arg Ala Leu Glu Thr Tyr
                  35                  40                  45

 Gln Ser His Lys Asn Leu Ile Pro Phe Arg Pro Ser Ile Gln Phe
                  50                  55                  60

 Gln Gly Leu His Gly Leu Val Lys Ile Pro Lys Asn Asp Pro Leu
                  65                  70                  75

 Asn Glu Val His Asn Phe Asn Phe Tyr Leu Ser Asn Val Gly Lys
                  80                  85                  90

 Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile Gln Gln Thr Phe Ser
                  95                 100                 105

 Ser Ser Gly Ala Ser Gln Leu Asn Cys Leu Gly Phe Ile Gln Asp
                 110                 115                 120

 Lys Ile Thr Val Cys Ala Thr Asn Asp Ser Tyr Gln Met Thr Arg
                 125                 130                 135

 Glu Arg Met Thr Gln Ala Glu Glu Glu Ser Arg Asn Arg Ser Thr
                 140                 145                 150

 Lys Val Ile Lys Pro Gly Gly Pro Tyr Val Gly Lys Arg Val Gln
                 155                 160                 165

 Ile Arg Lys Ala Pro Gln Ala Val Ser Asp Thr Val Pro Glu Arg
                 170                 175                 180

 Lys Arg Ser Thr Pro Met Asn Pro Ala Asn Thr Ile Arg Lys Thr
                 185                 190                 195

 His Ser Ser Ser Thr Ile Ser Gln Arg Pro Tyr Arg Asp Arg Val
                 200                 205                 210

 Ile His Leu Leu Ala Leu Lys Ala Tyr Lys Lys Pro Glu Leu Leu
                 215                 220                 225

 Ala Arg Leu Gln Lys Asp Gly Val Asn Gln Lys Asp Lys Asn Ser
                 230                 235                 240

 Leu Gly Ala Ile Leu Gln Gln Val Ala Asn Leu Asn Ser Lys Asp
                 245                 250                 255

 Leu Ser Tyr Thr Leu Lys Asp Tyr Val Phe Lys Glu Leu Gln Arg
                 260                 265                 270

 Asp Trp Pro Gly Tyr Ser Glu Ile Asp Arg Arg Ser Leu Glu Ser
                 275                 280                 285

 Val Leu Ser Arg Lys Leu Asn Pro Ser Gln Asn Ala Thr Gly Thr
                 290                 295                 300

 Ser Arg Ser Glu Ser Pro Val Cys Ser Ser Arg Asp Ala Val Ser
                 305                 310                 315

 Ser Pro Gln Lys Arg Leu Leu Asp Ser Glu Phe Ile Asp Pro Leu
                 320                 325                 330

 Met Asn Lys Lys Ala Arg Ile Ser His Leu Thr Asn Arg Val Pro
                 335                 340                 345

 Pro Thr Leu Asn Gly His Leu Asn Pro Thr Ser Glu Lys Ser Ala
                 350                 355                 360

 Ala Gly Leu Pro Leu Pro Pro Ala Ala Ala Ala Ile Pro Thr Pro
                 365                 370                 375

 Pro Pro Leu Pro Ser Thr Tyr Leu Pro Ile Ser His Pro Pro Gln
                 380                 385                 390

 Ile Val Asn Ser Asn Ser Asn Ser Pro Ser Thr Pro Glu Gly Arg
                 395                 400                 405

 Gly Thr Gln Asp Leu Pro Val Asp Ser Phe Ser Gln Asn Asp Ser
                 410                 415                 420

 Ile Tyr Glu Asp Gln Gln Asp Lys Tyr Thr Ser Arg Thr Ser Leu
                 425                 430                 435

 Glu Thr Leu Pro Pro Gly Ser Val Leu Leu Lys Cys Pro Lys Pro
                 440                 445                 450

 Met Glu Glu Asn His Ser Met Ser His Lys Lys Ser Lys Lys Lys
                 455                 460                 465

 Ser Lys Lys His Lys Glu Lys Asp Gln Ile Lys Lys His Asp Ile
                 470                 475                 480

 Glu Thr Ile Glu Glu Lys Glu Glu Asp Leu Lys Arg Glu Glu Glu
                 485                 490                 495

 Ile Ala Lys Leu Asn Asn Ser Ser Pro Asn Ser Ser Gly Gly Val
                 500                 505                 510

 Lys Glu Asp Cys Thr Ala Ser Met Glu Pro Ser Ala Ile Glu Leu
                 515                 520                 525

 Pro Asp Tyr Leu Ile Lys Tyr Ile Ala Ile Val Ser Tyr Glu Gln
                 530                 535                 540

 Arg Gln Asn Tyr Lys Asp Asp Phe Asn Ala Glu Tyr Asp Glu Tyr
                 545                 550                 555

 Arg Ala Leu His Ala Arg Met Glu Thr Val Ala Arg Arg Phe Ile
                 560                 565                 570

 Lys Leu Asp Ala Gln Arg Lys Arg Leu Ser Pro Gly Ser Lys Glu
                 575                 580                 585

 Tyr Gln Asn Val His Glu Glu Val Leu Gln Glu Tyr Gln Lys Ile
                 590                 595                 600

 Lys Gln Ser Ser Pro Asn Tyr His Glu Glu Lys Tyr Arg Cys Glu
                 605                 610                 615

 Tyr Leu His Asn Lys Leu Ala His Ile Lys Arg Leu Ile Gly Glu
                 620                 625                 630

 Phe Asp Gln Gln Gln Ala Glu Ser Trp Ser
                 635                 640

<210> 2906
<211> 1292
<212> DNA
<213> Homo sapien

<400> 2906
 tgcgcggctt cctgcctcca tgccactcca gactgcaccg gcatggcact 50

 gactgcccac ccctcctgcc tcctggccct gttggtggca ggcctagccc 100

 aaggcatcag aggccccctt agggcccagg acctaggtcc ccagccgcta 150

 gagctgaaag aggccttcaa gttgttccag atccagttca accggagtta 200

 cctgagccca gaagagcatg ctcaccgcct ggacatcttt gcccacaacc 250

 tggcccaggc tcagaggctg caggaggagg acttgggcac agctgagttt 300

 ggggtgactc cattcagtga cctcacagag gaggagtttg gccagctcta 350

 tggctatcgg agggcagctg gaggggtccc cagcatgggc agagaaataa 400

 ggtctgaaga gccagaggag tcagtacctt tcagctgtga ctggcggaag 450

 gtggccggcg ccatctcacc catcaaggac cagaaaaact gcaactgctg 500

 ctgggccatg gcagcggcag gcaacataga gaccctgtgg cgcatcagtt 550

 tctgggattt tgtggacgtc tccgtgcagg aactgctgga ctgtggccgc 600

 tgtggggatg gctgccacgg tggcttcgtc tgggacgcgt tcataactgt 650

 cctcaacaac agcggcctgg ccagtgaaaa ggactacccg ttccagggca 700

 aagtcagagc ccacaggtgc caccccaaga agtaccagaa ggtggcctgg 750

 atccaggact tcatcatgct gcagaacaac gagcacagaa ttgcgcagta 800

 cctggccact tatggcccca tcaccgtgac catcaacatg aagccccttc 850

 agctataccg gaaaggtgtg atcaaggcca cacccaccac ctgtgacccc 900

 cagcttgtgg accactctgt cctgctggtg ggttttggca gcgtcaagtc 950

 agaggagggg atatgggcag agacagtctc atcgcagtct cagcctcagc 1000

 ctccacaccc caccccatac tggatcctga agaactcctg gggggcccaa 1050

 tggggagaga agggctattt ccggctgcac cgagggagca atacctgtgg 1100

 catcaccaag ttcccgctca ctgcccgtgt gcagaaaccg gatatgaagc 1150

 cccgagtctc ctgccctccc tgaccacctg gccccctcag ctctgtcctg 1200

 ttaggccaac tgcctccttg ccagccccac ccccaggttt ttgcccatcc 1250

 tcccaatctc aatacagcct gaataaacca agacaagacc tc 1292

<210> 2907
<211> 376
<212> PRT
<213> Homo sapien

<400> 2907
 Met Ala Leu Thr Ala His Pro Ser Cys Leu Leu Ala Leu Leu Val
   1               5                  10                  15

 Ala Gly Leu Ala Gln Gly Ile Arg Gly Pro Leu Arg Ala Gln Asp
                  20                  25                  30

 Leu Gly Pro Gln Pro Leu Glu Leu Lys Glu Ala Phe Lys Leu Phe
                  35                  40                  45

 Gln Ile Gln Phe Asn Arg Ser Tyr Leu Ser Pro Glu Glu His Ala
                  50                  55                  60

 His Arg Leu Asp Ile Phe Ala His Asn Leu Ala Gln Ala Gln Arg
                  65                  70                  75

 Leu Gln Glu Glu Asp Leu Gly Thr Ala Glu Phe Gly Val Thr Pro
                  80                  85                  90

 Phe Ser Asp Leu Thr Glu Glu Glu Phe Gly Gln Leu Tyr Gly Tyr
                  95                 100                 105

 Arg Arg Ala Ala Gly Gly Val Pro Ser Met Gly Arg Glu Ile Arg
                 110                 115                 120

 Ser Glu Glu Pro Glu Glu Ser Val Pro Phe Ser Cys Asp Trp Arg
                 125                 130                 135

 Lys Val Ala Gly Ala Ile Ser Pro Ile Lys Asp Gln Lys Asn Cys
                 140                 145                 150

 Asn Cys Cys Trp Ala Met Ala Ala Ala Gly Asn Ile Glu Thr Leu
                 155                 160                 165

 Trp Arg Ile Ser Phe Trp Asp Phe Val Asp Val Ser Val Gln Glu
                 170                 175                 180

 Leu Leu Asp Cys Gly Arg Cys Gly Asp Gly Cys His Gly Gly Phe
                 185                 190                 195

 Val Trp Asp Ala Phe Ile Thr Val Leu Asn Asn Ser Gly Leu Ala
                 200                 205                 210

 Ser Glu Lys Asp Tyr Pro Phe Gln Gly Lys Val Arg Ala His Arg
                 215                 220                 225

 Cys His Pro Lys Lys Tyr Gln Lys Val Ala Trp Ile Gln Asp Phe
                 230                 235                 240

 Ile Met Leu Gln Asn Asn Glu His Arg Ile Ala Gln Tyr Leu Ala
                 245                 250                 255

 Thr Tyr Gly Pro Ile Thr Val Thr Ile Asn Met Lys Pro Leu Gln
                 260                 265                 270

 Leu Tyr Arg Lys Gly Val Ile Lys Ala Thr Pro Thr Thr Cys Asp
                 275                 280                 285

 Pro Gln Leu Val Asp His Ser Val Leu Leu Val Gly Phe Gly Ser
                 290                 295                 300

 Val Lys Ser Glu Glu Gly Ile Trp Ala Glu Thr Val Ser Ser Gln
                 305                 310                 315

 Ser Gln Pro Gln Pro Pro His Pro Thr Pro Tyr Trp Ile Leu Lys
                 320                 325                 330

 Asn Ser Trp Gly Ala Gln Trp Gly Glu Lys Gly Tyr Phe Arg Leu
                 335                 340                 345

 His Arg Gly Ser Asn Thr Cys Gly Ile Thr Lys Phe Pro Leu Thr
                 350                 355                 360

 Ala Arg Val Gln Lys Pro Asp Met Lys Pro Arg Val Ser Cys Pro
                 365                 370                 375

 Pro


<210> 2908
<211> 1714
<212> DNA
<213> Homo sapien

<400> 2908
 ggggcatttt gtgcctgcct agctatccag acagagcagc taccctcagc 50

 tctagctgat actacagaca gtacaacaga tcaagaagta tggcagtgac 100

 aactcgtttg acacggttgc acgaaaagat cctgcaaaat cattttggag 150

 ggaagcggct tagccttctc tataagggta gtgtccatgg attccgtaat 200

 ggagttttgc ttgacagatg ttgtaatcaa gggcctactc taacagtgat 250

 ttatagtgaa gatcatatta ttggagcata tgcggaagag agttaccagg 300

 aaggaaagta tgcttccatc atcctttttg cacttcaaga tactaaaatt 350

 tcagaatgga aactaggact atgtacacca gaaacactgt tttgttgtga 400

 tgttacaaaa tataactccc caactaattt ccagatagat ggaagaaata 450

 gaaaagtgat tatggactta aagacaatgg aaaatcttgg acttgctcaa 500

 aattgtacta tctctattca ggattatgaa gtttttcgat gcgaagattc 550

 actggatgaa agaaagataa aaggggtcat tgagctcagg aagagcttac 600

 tgtctgcctt gagaacttat gaaccatatg gatccctggt tcaacaaata 650

 cgaattctgc tgctgggtcc aattggagct gggaagtcca gctttttcaa 700

 ctcagtgagg tctgttttcc aagggcatgt aacgcatcag gctttggtgg 750

 gcactaatac aactgggata tctgagaagt ataggacata ctctattaga 800

 gacgggaaag atggcaaata cctgccgttt attctgtgtg actcactggg 850

 gctgagtgag aaagaaggcg gcctgtgcag ggatgacata ttctatatct 900

 tgaacggtaa cattcgtgat agataccagt ttaatcccat ggaatcaatc 950

 aaattaaatc atcatgacta cattgattcc ccatcgctga aggacagaat 1000

 tcattgtgtg gcatttgtat ttgatgccag ctctattcaa tacttctcct 1050

 ctcagatgat agtaaagatc aaaagaattc gaagggagtt ggtaaacgct 1100

 ggtgtggtac atgtggcttt gctcactcat gtggatagca tggatttgat 1150

 tacaaaaggt gaccttatag aaatagagag atgtgagcct gtgaggtcca 1200

 agctagagga agtccaaaga aaacttggat ttgctctttc tgacatctcg 1250

 gtggttagca attattcctc tgagtgggag ctggaccctg taaaggatgt 1300

 tctaattctt tctgctctga gacgaatgct atgggctgca gatgacttct 1350

 tagaggattt gccttttgag caaataggga atctaaggga ggaaattatc 1400

 aactgtgcac aaggaaaaaa atagatatgt gaaaggttca cgtaaatttc 1450

 ctcacatcac agaagattaa aattcagaaa ggagaaaaca cagaccaaag 1500

 agaagtatct aagaccaaag ggatgtgttt tattaatgtc taggatgaag 1550

 aaatgcatag aacattgtag tacttgtaaa taactagaaa taacatgatt 1600

 tagtcataat tgtgaaaaat agtaataatt tttcttggat ttatgttctg 1650

 tatctgtgaa aaaataaatt tcttataaaa ctcggaaaaa aaaaaaaaaa 1700

 aaaaaaaaaa aaaa 1714

<210> 2909
<211> 444
<212> PRT
<213> Homo sapien

<400> 2909
 Met Ala Val Thr Thr Arg Leu Thr Arg Leu His Glu Lys Ile Leu
   1               5                  10                  15

 Gln Asn His Phe Gly Gly Lys Arg Leu Ser Leu Leu Tyr Lys Gly
                  20                  25                  30

 Ser Val His Gly Phe Arg Asn Gly Val Leu Leu Asp Arg Cys Cys
                  35                  40                  45

 Asn Gln Gly Pro Thr Leu Thr Val Ile Tyr Ser Glu Asp His Ile
                  50                  55                  60

 Ile Gly Ala Tyr Ala Glu Glu Ser Tyr Gln Glu Gly Lys Tyr Ala
                  65                  70                  75

 Ser Ile Ile Leu Phe Ala Leu Gln Asp Thr Lys Ile Ser Glu Trp
                  80                  85                  90

 Lys Leu Gly Leu Cys Thr Pro Glu Thr Leu Phe Cys Cys Asp Val
                  95                 100                 105

 Thr Lys Tyr Asn Ser Pro Thr Asn Phe Gln Ile Asp Gly Arg Asn
                 110                 115                 120

 Arg Lys Val Ile Met Asp Leu Lys Thr Met Glu Asn Leu Gly Leu
                 125                 130                 135

 Ala Gln Asn Cys Thr Ile Ser Ile Gln Asp Tyr Glu Val Phe Arg
                 140                 145                 150

 Cys Glu Asp Ser Leu Asp Glu Arg Lys Ile Lys Gly Val Ile Glu
                 155                 160                 165

 Leu Arg Lys Ser Leu Leu Ser Ala Leu Arg Thr Tyr Glu Pro Tyr
                 170                 175                 180

 Gly Ser Leu Val Gln Gln Ile Arg Ile Leu Leu Leu Gly Pro Ile
                 185                 190                 195

 Gly Ala Gly Lys Ser Ser Phe Phe Asn Ser Val Arg Ser Val Phe
                 200                 205                 210

 Gln Gly His Val Thr His Gln Ala Leu Val Gly Thr Asn Thr Thr
                 215                 220                 225

 Gly Ile Ser Glu Lys Tyr Arg Thr Tyr Ser Ile Arg Asp Gly Lys
                 230                 235                 240

 Asp Gly Lys Tyr Leu Pro Phe Ile Leu Cys Asp Ser Leu Gly Leu
                 245                 250                 255

 Ser Glu Lys Glu Gly Gly Leu Cys Arg Asp Asp Ile Phe Tyr Ile
                 260                 265                 270

 Leu Asn Gly Asn Ile Arg Asp Arg Tyr Gln Phe Asn Pro Met Glu
                 275                 280                 285

 Ser Ile Lys Leu Asn His His Asp Tyr Ile Asp Ser Pro Ser Leu
                 290                 295                 300

 Lys Asp Arg Ile His Cys Val Ala Phe Val Phe Asp Ala Ser Ser
                 305                 310                 315

 Ile Gln Tyr Phe Ser Ser Gln Met Ile Val Lys Ile Lys Arg Ile
                 320                 325                 330

 Arg Arg Glu Leu Val Asn Ala Gly Val Val His Val Ala Leu Leu
                 335                 340                 345

 Thr His Val Asp Ser Met Asp Leu Ile Thr Lys Gly Asp Leu Ile
                 350                 355                 360

 Glu Ile Glu Arg Cys Glu Pro Val Arg Ser Lys Leu Glu Glu Val
                 365                 370                 375

 Gln Arg Lys Leu Gly Phe Ala Leu Ser Asp Ile Ser Val Val Ser
                 380                 385                 390

 Asn Tyr Ser Ser Glu Trp Glu Leu Asp Pro Val Lys Asp Val Leu
                 395                 400                 405

 Ile Leu Ser Ala Leu Arg Arg Met Leu Trp Ala Ala Asp Asp Phe
                 410                 415                 420

 Leu Glu Asp Leu Pro Phe Glu Gln Ile Gly Asn Leu Arg Glu Glu
                 425                 430                 435

 Ile Ile Asn Cys Ala Gln Gly Lys Lys
                 440

<210> 2910
<211> 738
<212> DNA
<213> Homo sapien

<400> 2910
 aaagcagaat tgagagtttg ttcttacaca caagtttaat gccaccttcc 50

 tctgtctgcc atggaccaac aagcaatata tgctgagtta aacttaccca 100

 cagactcagg cccagaaagt tcttcacctt catctcttcc tcgggatgtc 150

 tgtcagggtt caccttggca tcaatttgcc ctgaaactta gctgtgctgg 200

 gattattctc cttgtcttgg ttgttactgg gttgagtgtt tcagtgacat 250

 ccttaataca gaaatcatca atagaaaaat gcagtgtgga cattcaacag 300

 agcaggaata aaacaacaga gagaccgggt ctcttaaact gcccaatata 350

 ttggcagcaa ctccgagaga aatgcttgtt attttctcac actgtcaacc 400

 cttggaataa cagtctagct gattgttcca ccaaagaatc cagcctgctg 450

 cttattcgag ataaggatga attgatacac acacagaacc tgatacgtga 500

 caaagcaatt ctgttttgga ttggattaaa tttttcatta tcagaaaaga 550

 actggaagtg gataaacggc tcttttttaa attctaatga cttagaaatt 600

 agaggtgatg ctaaagaaaa cagctgtatt tccatctcac agacatctgt 650

 gtattctgag tactgtagta cagaaatcag atggatctgc caaaaagaac 700

 taacacctgt gagaaataaa gtgtatcctg actcttga 738

<210> 2911
<211> 225
<212> PRT
<213> Homo sapien

<400> 2911
 Met Asp Gln Gln Ala Ile Tyr Ala Glu Leu Asn Leu Pro Thr Asp
   1               5                  10                  15

 Ser Gly Pro Glu Ser Ser Ser Pro Ser Ser Leu Pro Arg Asp Val
                  20                  25                  30

 Cys Gln Gly Ser Pro Trp His Gln Phe Ala Leu Lys Leu Ser Cys
                  35                  40                  45

 Ala Gly Ile Ile Leu Leu Val Leu Val Val Thr Gly Leu Ser Val
                  50                  55                  60

 Ser Val Thr Ser Leu Ile Gln Lys Ser Ser Ile Glu Lys Cys Ser
                  65                  70                  75

 Val Asp Ile Gln Gln Ser Arg Asn Lys Thr Thr Glu Arg Pro Gly
                  80                  85                  90

 Leu Leu Asn Cys Pro Ile Tyr Trp Gln Gln Leu Arg Glu Lys Cys
                  95                 100                 105

 Leu Leu Phe Ser His Thr Val Asn Pro Trp Asn Asn Ser Leu Ala
                 110                 115                 120

 Asp Cys Ser Thr Lys Glu Ser Ser Leu Leu Leu Ile Arg Asp Lys
                 125                 130                 135

 Asp Glu Leu Ile His Thr Gln Asn Leu Ile Arg Asp Lys Ala Ile
                 140                 145                 150

 Leu Phe Trp Ile Gly Leu Asn Phe Ser Leu Ser Glu Lys Asn Trp
                 155                 160                 165

 Lys Trp Ile Asn Gly Ser Phe Leu Asn Ser Asn Asp Leu Glu Ile
                 170                 175                 180

 Arg Gly Asp Ala Lys Glu Asn Ser Cys Ile Ser Ile Ser Gln Thr
                 185                 190                 195

 Ser Val Tyr Ser Glu Tyr Cys Ser Thr Glu Ile Arg Trp Ile Cys
                 200                 205                 210

 Gln Lys Glu Leu Thr Pro Val Arg Asn Lys Val Tyr Pro Asp Ser
                 215                 220                 225

<210> 2912
<211> 723
<212> DNA
<213> Homo sapien

<400> 2912
 atggccgggc ctccgaggct cctgctgctg cccctgcttc tggcgctggc 50

 tcgcggcctg cctggggccc tggctgccca agaggtgcag cagtctcccc 100

 actgcacgac tgtccccgtg ggagcctccg tcaacatcac ctgctccacc 150

 agcgggggcc tgcgtgggat ctacctgagg cagctcgggc cacagcccca 200

 agacatcatt tactacgagg acggggtggt gcccactacg gacagacggt 250

 tccggggccg catcgacttc tcagggtccc aggacaacct gactatcacc 300

 atgcaccgcc tgcagctgtc ggacactggc acctacacct gccaggccat 350

 cacggaggtc aatgtctacg gctccggcac cctggtcctg gtgacagagg 400

 aacagtccca aggatggcac agatgctcgg acgccccacc aagggcctct 450

 gccctccctg ccccaccgac aggctccgcc ctccctgacc cgcagacagc 500

 ctctgccctc cctgacccgc cagcagcctc tgccctccct gcggccctgg 550

 cggtgatctc cttcctcctc gggctgggcc tgggggtggc gtgtgtgctg 600

 gcgaggacac agataaagaa actgtgctcg tggcgggata agaattcggc 650

 ggcatgtgtg gtgtacgagg acatgtcgca cagccgctgc aacacgctgt 700

 cctcccccaa ccagtaccag tga 723

<210> 2913
<211> 240
<212> PRT
<213> Homo sapien

<400> 2913
 Met Ala Gly Pro Pro Arg Leu Leu Leu Leu Pro Leu Leu Leu Ala
   1               5                  10                  15

 Leu Ala Arg Gly Leu Pro Gly Ala Leu Ala Ala Gln Glu Val Gln
                  20                  25                  30

 Gln Ser Pro His Cys Thr Thr Val Pro Val Gly Ala Ser Val Asn
                  35                  40                  45

 Ile Thr Cys Ser Thr Ser Gly Gly Leu Arg Gly Ile Tyr Leu Arg
                  50                  55                  60

 Gln Leu Gly Pro Gln Pro Gln Asp Ile Ile Tyr Tyr Glu Asp Gly
                  65                  70                  75

 Val Val Pro Thr Thr Asp Arg Arg Phe Arg Gly Arg Ile Asp Phe
                  80                  85                  90

 Ser Gly Ser Gln Asp Asn Leu Thr Ile Thr Met His Arg Leu Gln
                  95                 100                 105

 Leu Ser Asp Thr Gly Thr Tyr Thr Cys Gln Ala Ile Thr Glu Val
                 110                 115                 120

 Asn Val Tyr Gly Ser Gly Thr Leu Val Leu Val Thr Glu Glu Gln
                 125                 130                 135

 Ser Gln Gly Trp His Arg Cys Ser Asp Ala Pro Pro Arg Ala Ser
                 140                 145                 150

 Ala Leu Pro Ala Pro Pro Thr Gly Ser Ala Leu Pro Asp Pro Gln
                 155                 160                 165

 Thr Ala Ser Ala Leu Pro Asp Pro Pro Ala Ala Ser Ala Leu Pro
                 170                 175                 180

 Ala Ala Leu Ala Val Ile Ser Phe Leu Leu Gly Leu Gly Leu Gly
                 185                 190                 195

 Val Ala Cys Val Leu Ala Arg Thr Gln Ile Lys Lys Leu Cys Ser
                 200                 205                 210

 Trp Arg Asp Lys Asn Ser Ala Ala Cys Val Val Tyr Glu Asp Met
                 215                 220                 225

 Ser His Ser Arg Cys Asn Thr Leu Ser Ser Pro Asn Gln Tyr Gln
                 230                 235                 240

<210> 2914
<211> 547
<212> DNA
<213> Homo sapien

<400> 2914
 gcgggacctc agccatgaga cttctcatcc tggccctcct tggcatctgc 50

 tctctcactg catacattgt ggaaggtgta gggagtgaag tctcagataa 100

 gaggacctgt gtgagcctca ctacccagcg actgccggtt agcagaatca 150

 agacctacac catcacggaa ggctccttga gagcagtaat ttttattacc 200

 aaacgtggcc taaaagtctg tgctgatcca caagccacgt gggtgagaga 250

 cgtggtcagg agcatggaca ggaaatccaa caccagaaat aacatgatcc 300

 agaccaagcc aacaggaacc cagcaatcga ccaatacagc tgtgaccctg 350

 actggctagt agtctctggc accctgtccg tctccagcca gccagctcat 400

 ttcactttac accctcatgg actgagttta tactcacctt ttatgaaagc 450

 actgcatgaa taaaattatt cctttgtatt tttactttta aatgtcttct 500

 gtattcactt atatgttcta attaataaat tatttattat taagaat 547

<210> 2915
<211> 114
<212> PRT
<213> Homo sapien

<400> 2915
 Met Arg Leu Leu Ile Leu Ala Leu Leu Gly Ile Cys Ser Leu Thr
   1               5                  10                  15

 Ala Tyr Ile Val Glu Gly Val Gly Ser Glu Val Ser Asp Lys Arg
                  20                  25                  30

 Thr Cys Val Ser Leu Thr Thr Gln Arg Leu Pro Val Ser Arg Ile
                  35                  40                  45

 Lys Thr Tyr Thr Ile Thr Glu Gly Ser Leu Arg Ala Val Ile Phe
                  50                  55                  60

 Ile Thr Lys Arg Gly Leu Lys Val Cys Ala Asp Pro Gln Ala Thr
                  65                  70                  75

 Trp Val Arg Asp Val Val Arg Ser Met Asp Arg Lys Ser Asn Thr
                  80                  85                  90

 Arg Asn Asn Met Ile Gln Thr Lys Pro Thr Gly Thr Gln Gln Ser
                  95                 100                 105

 Thr Asn Thr Ala Val Thr Leu Thr Gly
                 110

<210> 2916
<211> 1296
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 71-72, 75, 77
<223> Unknown base

<400> 2916
 gcagggttcg actctagagg atccccctgg ggcccttact ctagcgggta 50

 ctcactctgt cgtgcgagaa nncananctt attttccagg tggcagtgct 100

 ccttttggac ttttctctag gtttggcgct aaactcttct tgtgagctca 150

 ctccacccct tcttcctccc tttaacttat ccattcactt aaaacattag 200

 ctggtcatct ggtaagcccg ggacagtaag ccgagtggct gttggagtcg 250

 gtattgttgg taatggtgga ggaagagagg ccttcccgct gaggctgggg 300

 tggggcggat cggtgttgct tgcctgcaga gagggtgggg agtgaatgtg 350

 cacccttggg tgggcctgca gccatccagc tgaaagttac aaaaatgctt 400

 catggaccgt ggtttgttac tatagtgttc ctcatggcga gcagatggaa 450

 ccgggagaca tggagtccct ggccagtgtg agtcctagca ttgcaggagg 500

 ggagaccctg gaggagagag cccgcctcaa ttgatgcctg cagattgaat 550

 ttccagaggc ttaggaggag gaagttctcc aatgttctgt tttccaggcc 600

 ttgcttcagg aagccctgta ttcaggaggc taccatttaa agtttgcaga 650

 tgagcttatg gggggcaaac cttaaaaagt cccacagcag atgcatccgg 700

 cctcgagggg cccatcagct ttgaaataaa tgcttgttcc agagccccat 750

 gaaatgccag caggcacccc tcctttcctc ggggtaaagg ttttcagatg 800

 ctgcatcttc ctaaaattga gcctccggtc atactagttt tgtgcttggg 850

 aaccttgctt caagaagatc cctaagctgt agaacatttt aacgttgatg 900

 ccacaacgca gattgatgcc ttgtagatgg agcttgcaga tggagccccg 950

 tgacctctca cctacccacc tgtttgcctg ccttcttgtg cgtttctcgg 1000

 agaagttctt agcctgatga aataacttgg ggcgttgaag agctgtttaa 1050

 ttttaaatgc cttagactgg ggatatatta gaggaagcag attgtcaaat 1100

 taagggtgtc attgtgttgt gctaaacgct gggagggtac aagttggtca 1150

 ttcctaaatc tgtgtgtgag aaatggcagg tctagcttgg gcattgtgat 1200

 tgcattgcag attactagga gaagggaatg gtgggtacac cggtagtgct 1250

 cttttgttct tgcttcgttt ttttaaactt gaactttaca acgtta 1296

<210> 2917
<211> 22
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 71-72, 75, 77
<223> Unknown amino acid

<400> 2917
 Met Val Gly Thr Pro Val Val Leu Phe Cys Ser Cys Phe Val Phe
   1               5                  10                  15

 Leu Asn Leu Asn Phe Thr Thr
                  20

<210> 2918
<211> 3500
<212> DNA
<213> Homo sapien

<400> 2918
 cacgtggctg cagcggggcc agagcagcaa tggcggcggg cggcggcggt 50

 agctgcgacc ccctggcccc tgctggggtc ccttgcgcct tctccccgca 100

 cagccaggcc tacttcgctt tggcctctac cgacggtcac ttacgagtat 150

 gggagacggc caacaaccgg ctgcaccagg agtacgtgcc ttccgcgcac 200

 ctcagtggta cctgcacctg tctggcctgg gcgccagcgc ggctgcaggc 250

 caaggaaagt ccccagagga aaaaaaggaa atcagaagct gtaggaatga 300

 gtaaccagac tgacttattg gctcttggca cagcagttgg tagcatttta 350

 ttatacagca cagtaaaagg agagttacac agtaaattaa taagtggtgg 400

 acatgacaac agagtcaact gcatacagtg gcatcaagac agtggctgtt 450

 tatatagttg ttcagatgat aaacatattg tggaatggaa cgtacagaca 500

 tgcaaagtaa agtgcaaatg gaaaggggac aatagcagtg tcagttccct 550

 atgtatcagc ccagatggaa agatgttgct ttcagctggt cgaacaatca 600

 aactatgggt tttggagacc aaagaagtct acaggcattt cacaggacat 650

 gcaacgccag tttcgtcact gatgttcact accatcagac ctcctaatga 700

 gagccagccc tttgatggaa ttacaggtct ttatttctta tctggagcag 750

 tacatgaccg gttacttaat gtctggcagg tccgatcaga aaacaaagaa 800

 aagagtgcag tgatgtcatt tacagttacc gatgaacctg tctatattga 850

 cttaactttg tcagaaaaca aagaagagcc tgtcaagttg gctgttgttt 900

 gcagagatgg tcaagtccat ctttttgaac acatattaaa tgggtactgc 950

 aaaaagcctt tgacttcaaa ctgcacaatt cagatagcaa cacctgggaa 1000

 aggcaagaag tcaacaccaa aacccatccc tattctagct gctggttttt 1050

 gctcagacaa aatgtcattg ttgcttgtat atggcagttg gtttcagcct 1100

 actattgagc gagtggcttt aaactccaga gaacctcata tgtgtttagt 1150

 aagagatatt tcaaactgct gggcccccaa agtagaaaca gctataacaa 1200

 aggtgaggac accagtgatg aattctgaag caaaagttct ggtgcctggg 1250

 attcctggtc atcatgcagc tatcaagccc gctcctccac aaaccgagca 1300

 agtagagagc aagaggaagt cagggggaaa tgaggttagc attgaagaac 1350

 gtctgggagc aatggatata gacacacaca aaaaaggaaa ggaagacctc 1400

 cagacgaata gctttccagt tcttcttacc cagggcttag aaagtaacga 1450

 ttttgaaatg ctaaataaag tacttcaaac taggaatgta aaccttataa 1500

 agaagactgt attaaggatg cccctgcata ctattattcc gttgttacaa 1550

 gagcttacaa agaggttaca aggacatcct aatagtgctg tgctaatggt 1600

 tcagtggcta aaatgtgtgt taacagttca tgcatcatac ctgtccacgt 1650

 tgcctgacct ggtaccccag ctggggacac tctaccagtt aatggaaagc 1700

 agagtcaaaa cttttcagaa actttcacac cttcatggaa agcttattct 1750

 tctaattaca caagtaacag catcagagaa gacaaaggga gcaacttccc 1800

 ctggacagaa ggcaaagttg gtgtatgaag aagagtcttc tgaagaggag 1850

 tctgatgatg aaatagcaga taaggattct gaagataatt gggatgaaga 1900

 tgaggaggag agtgaaagtg aaaaagatga ggacgttgaa gaggaagatg 1950

 aggatgccga aggaaaagat gaagaaaatg gcgaggacag agatacagca 2000

 agtgaaaaag aattaaatgg agattctgac ttagatcctg aaaatgaaag 2050

 tgaagaagaa tgaagacagc aaagcaagcc ggtcaaacta tataaactct 2100

 ggctcacctt gcccagtggt gagggctgcc tctgtgccag gatgccaagg 2150

 accgctgcac atttccaaat tcacagcagt ggatcccatg ccactttgct 2200

 gtcctgagca ccccagactt gactgtgtaa ataagagtgt ttcattcaaa 2250

 tgttaataaa ctttacacag tatatagaca cattttctgc aatgtactga 2300

 catcagtgtc caatatatgg tatattttta taatataata tcctagtatg 2350

 attggttata tcaagaattg acaagtgcag ataaagacct ttcccatagg 2400

 agttcaagaa ctggactgtt gtgaagaagt cagctcttat ctcaggttgg 2450

 tatctttcat caaatccaga tgcaaagcag cactagtgaa aattttttta 2500

 atttagtaca tttaatttgg tacattttca taaaatatga agggataact 2550

 acaaactgga gtaaaaatga tggtaattaa aaaaaatcct cagtatccct 2600

 agcttgtcta ttaactgtga taatctgact tgagtcagat tgaatatttg 2650

 gagtgcttcc ccagaataac cacttatttt tgaagctatc atgtgaagta 2700

 tttttttaaa acaaaacaaa aattatggtc attaaaaaac tagagaatta 2750

 gccatattaa ggatttttct tgactgcaaa ttacttctaa agaatcatca 2800

 gtgtatagat tagaagtgct cattacctgc aacttttaaa aaaaattcag 2850

 ttatagctgc ttttgaagag gtttccattt ttatttaaat tactaatgga 2900

 tcaaagaaca attgtttatt ttttctcttt ggttttagat attaatgata 2950

 accttgttgg aatttttttt ccaaagaaaa tatttttata attaaataat 3000

 ttaatgtttt tcttcctttt cattacctac tcttggcagt gttagggtat 3050

 ctgtttacct ttaaaatgat aagtctcact caagattttt tatctatgta 3100

 taaatatttt ggtgtgctac aaaagccttt acaaattatc agtagtagtt 3150

 tttttttttt tttttttttt taaagaatga gccgatattg gcttagtgct 3200

 cactagggga catgcacatg gaagctcacc tctaagaaag ggctgggcag 3250

 atggatttat tttttcccac ctgtgaatat gtaaaacaaa accattatct 3300

 ttgagggagt ttttaatacc aatgacagaa cagagatttg tgtgctcatc 3350

 ttaagagcca gagccatata agcatcttgg gaaagcaagt ttgaaccagc 3400

 tgctggtgta atgtacagtt atatttgtct ataaatggag ctgtttatgg 3450

 caatttaata ccattctctt tgtaaagtga ataaatattc atcttttccc 3500

<210> 2919
<211> 686
<212> PRT
<213> Homo sapien

<400> 2919
 Arg Gly Cys Ser Gly Ala Arg Ala Ala Met Ala Ala Gly Gly Gly
   1               5                  10                  15

 Gly Ser Cys Asp Pro Leu Ala Pro Ala Gly Val Pro Cys Ala Phe
                  20                  25                  30

 Ser Pro His Ser Gln Ala Tyr Phe Ala Leu Ala Ser Thr Asp Gly
                  35                  40                  45

 His Leu Arg Val Trp Glu Thr Ala Asn Asn Arg Leu His Gln Glu
                  50                  55                  60

 Tyr Val Pro Ser Ala His Leu Ser Gly Thr Cys Thr Cys Leu Ala
                  65                  70                  75

 Trp Ala Pro Ala Arg Leu Gln Ala Lys Glu Ser Pro Gln Arg Lys
                  80                  85                  90

 Lys Arg Lys Ser Glu Ala Val Gly Met Ser Asn Gln Thr Asp Leu
                  95                 100                 105

 Leu Ala Leu Gly Thr Ala Val Gly Ser Ile Leu Leu Tyr Ser Thr
                 110                 115                 120

 Val Lys Gly Glu Leu His Ser Lys Leu Ile Ser Gly Gly His Asp
                 125                 130                 135

 Asn Arg Val Asn Cys Ile Gln Trp His Gln Asp Ser Gly Cys Leu
                 140                 145                 150

 Tyr Ser Cys Ser Asp Asp Lys His Ile Val Glu Trp Asn Val Gln
                 155                 160                 165

 Thr Cys Lys Val Lys Cys Lys Trp Lys Gly Asp Asn Ser Ser Val
                 170                 175                 180

 Ser Ser Leu Cys Ile Ser Pro Asp Gly Lys Met Leu Leu Ser Ala
                 185                 190                 195

 Gly Arg Thr Ile Lys Leu Trp Val Leu Glu Thr Lys Glu Val Tyr
                 200                 205                 210

 Arg His Phe Thr Gly His Ala Thr Pro Val Ser Ser Leu Met Phe
                 215                 220                 225

 Thr Thr Ile Arg Pro Pro Asn Glu Ser Gln Pro Phe Asp Gly Ile
                 230                 235                 240

 Thr Gly Leu Tyr Phe Leu Ser Gly Ala Val His Asp Arg Leu Leu
                 245                 250                 255

 Asn Val Trp Gln Val Arg Ser Glu Asn Lys Glu Lys Ser Ala Val
                 260                 265                 270

 Met Ser Phe Thr Val Thr Asp Glu Pro Val Tyr Ile Asp Leu Thr
                 275                 280                 285

 Leu Ser Glu Asn Lys Glu Glu Pro Val Lys Leu Ala Val Val Cys
                 290                 295                 300

 Arg Asp Gly Gln Val His Leu Phe Glu His Ile Leu Asn Gly Tyr
                 305                 310                 315

 Cys Lys Lys Pro Leu Thr Ser Asn Cys Thr Ile Gln Ile Ala Thr
                 320                 325                 330

 Pro Gly Lys Gly Lys Lys Ser Thr Pro Lys Pro Ile Pro Ile Leu
                 335                 340                 345

 Ala Ala Gly Phe Cys Ser Asp Lys Met Ser Leu Leu Leu Val Tyr
                 350                 355                 360

 Gly Ser Trp Phe Gln Pro Thr Ile Glu Arg Val Ala Leu Asn Ser
                 365                 370                 375

 Arg Glu Pro His Met Cys Leu Val Arg Asp Ile Ser Asn Cys Trp
                 380                 385                 390

 Ala Pro Lys Val Glu Thr Ala Ile Thr Lys Val Arg Thr Pro Val
                 395                 400                 405

 Met Asn Ser Glu Ala Lys Val Leu Val Pro Gly Ile Pro Gly His
                 410                 415                 420

 His Ala Ala Ile Lys Pro Ala Pro Pro Gln Thr Glu Gln Val Glu
                 425                 430                 435

 Ser Lys Arg Lys Ser Gly Gly Asn Glu Val Ser Ile Glu Glu Arg
                 440                 445                 450

 Leu Gly Ala Met Asp Ile Asp Thr His Lys Lys Gly Lys Glu Asp
                 455                 460                 465

 Leu Gln Thr Asn Ser Phe Pro Val Leu Leu Thr Gln Gly Leu Glu
                 470                 475                 480

 Ser Asn Asp Phe Glu Met Leu Asn Lys Val Leu Gln Thr Arg Asn
                 485                 490                 495

 Val Asn Leu Ile Lys Lys Thr Val Leu Arg Met Pro Leu His Thr
                 500                 505                 510

 Ile Ile Pro Leu Leu Gln Glu Leu Thr Lys Arg Leu Gln Gly His
                 515                 520                 525

 Pro Asn Ser Ala Val Leu Met Val Gln Trp Leu Lys Cys Val Leu
                 530                 535                 540

 Thr Val His Ala Ser Tyr Leu Ser Thr Leu Pro Asp Leu Val Pro
                 545                 550                 555

 Gln Leu Gly Thr Leu Tyr Gln Leu Met Glu Ser Arg Val Lys Thr
                 560                 565                 570

 Phe Gln Lys Leu Ser His Leu His Gly Lys Leu Ile Leu Leu Ile
                 575                 580                 585

 Thr Gln Val Thr Ala Ser Glu Lys Thr Lys Gly Ala Thr Ser Pro
                 590                 595                 600

 Gly Gln Lys Ala Lys Leu Val Tyr Glu Glu Glu Ser Ser Glu Glu
                 605                 610                 615

 Glu Ser Asp Asp Glu Ile Ala Asp Lys Asp Ser Glu Asp Asn Trp
                 620                 625                 630

 Asp Glu Asp Glu Glu Glu Ser Glu Ser Glu Lys Asp Glu Asp Val
                 635                 640                 645

 Glu Glu Glu Asp Glu Asp Ala Glu Gly Lys Asp Glu Glu Asn Gly
                 650                 655                 660

 Glu Asp Arg Asp Thr Ala Ser Glu Lys Glu Leu Asn Gly Asp Ser
                 665                 670                 675

 Asp Leu Asp Pro Glu Asn Glu Ser Glu Glu Glu
                 680                 685

<210> 2920
<211> 1834
<212> DNA
<213> Homo sapien

<400> 2920
 atttttagat aatcattaaa gaccacagaa aatgtaacag atcctactct 50

 tcaaaataat tgctattcag tattaaaacg agcagtcagc tgcgtgattc 100

 ccgtgattgc gttacaagct ttgtctcctt cgacttggag tctttgtcca 150

 ggacgatgag acactcaaag agaacttact gtcctgattg ggatgacaag 200

 gattgggatt atggaaaatg gaggagcagc agcagtcata aaagaaggaa 250

 gagatcacat agcagtgccc aggagaacaa gcgctgcaaa tacaatcact 300

 ctaaaatgtg tgatagccat tatttggaaa gcaggtctat aaatgagaaa 350

 gattatcata gtcgacgcta cattgatgag tacagaaatg actacactca 400

 aggatgtgaa cctggacatc gccaaagaga ccatgaaagc cggtatcaga 450

 accatagtag caagtcttct ggtagaagtg gaagaagtag ttataaaagc 500

 aaacacagga ttcaccacag tacttcacat cgtcgttcac atgggaagag 550

 tcaccgaagg aaaagaacca ggagtgtaga ggatgatgag gagggtcacc 600

 tgatctgtca gagtggagac gtactaagtg caagatatga aattgttgat 650

 actttaggtg aaggagcttt tggaaaagtt gtggagtgca tcgatcataa 700

 agcgggaggt agacatgtag cagtaaaaat agttaaaaat gtggatagat 750

 actgtgaagc tgctcgctca gaaatacaag ttctggaaca tctgaataca 800

 acagacccca acagtacttt ccgctgtgtc cagatgttgg aatggtttga 850

 gcatcatggt cacatttgca ttgtttttga actattggga cttagtactt 900

 acgacttcat taaagaaaat ggttttctac catttcgact ggatcatatc 950

 agaaagatgg catatcagat atgcaagtct gtgaattttt tgcacagtaa 1000

 taagttgact cacacagact taaagcctga aaacatctta tttgtgcagt 1050

 ctgactacac agaggcgtat aatcccaaaa taaaacgtga tgaacgcacc 1100

 ttaataaatc cagatattaa agttgtagac tttggtagtg caacatatga 1150

 tgacgaacat cacagtacat tggtatctac aagacattat agagcacctg 1200

 aagttatttt agccctaggg tggtcccaac catgtgatgt ctggagcata 1250

 ggatgcattc ttattgaata ctatcttggg tttaccgtat ttccaacaca 1300

 cgatagtaag gagcatttag caatgatgga aaggattctt ggacctctac 1350

 caaaacatat gatacagaaa accaggaaac gtaaatattt tcaccacgat 1400

 cgattagact gggatgaaca cagttctgcc ggcagatatg tttcaagagc 1450

 ctgtaaacct ctgaaggaat ttatgctttc tcaagatgtt gaacatgagc 1500

 gtctctttga cctcattcag aaaatgttgg agtatgatcc agccaaaaga 1550

 attactctca gagaagcctt aaagcatcct ttctttgacc ttctgaagaa 1600

 aagtatatag atctgtaatt ggacagctct ctcgaagaga tcttacagac 1650

 tgtatcagtc taatttttaa attttaagtt attttgtaca gctttgtaaa 1700

 ttcttaacat ttttatattg ccatgtttat tttgtttggg taatttggtt 1750

 cattaagtac atagctaagg taatgaacat ctttttcagt aattgtaaag 1800

 tgatttattc agaataaatt ttttgtgctt atga 1834

<210> 2921
<211> 484
<212> PRT
<213> Homo sapien

<400> 2921
 Met Arg His Ser Lys Arg Thr Tyr Cys Pro Asp Trp Asp Asp Lys
   1               5                  10                  15

 Asp Trp Asp Tyr Gly Lys Trp Arg Ser Ser Ser Ser His Lys Arg
                  20                  25                  30

 Arg Lys Arg Ser His Ser Ser Ala Gln Glu Asn Lys Arg Cys Lys
                  35                  40                  45

 Tyr Asn His Ser Lys Met Cys Asp Ser His Tyr Leu Glu Ser Arg
                  50                  55                  60

 Ser Ile Asn Glu Lys Asp Tyr His Ser Arg Arg Tyr Ile Asp Glu
                  65                  70                  75

 Tyr Arg Asn Asp Tyr Thr Gln Gly Cys Glu Pro Gly His Arg Gln
                  80                  85                  90

 Arg Asp His Glu Ser Arg Tyr Gln Asn His Ser Ser Lys Ser Ser
                  95                 100                 105

 Gly Arg Ser Gly Arg Ser Ser Tyr Lys Ser Lys His Arg Ile His
                 110                 115                 120

 His Ser Thr Ser His Arg Arg Ser His Gly Lys Ser His Arg Arg
                 125                 130                 135

 Lys Arg Thr Arg Ser Val Glu Asp Asp Glu Glu Gly His Leu Ile
                 140                 145                 150

 Cys Gln Ser Gly Asp Val Leu Ser Ala Arg Tyr Glu Ile Val Asp
                 155                 160                 165

 Thr Leu Gly Glu Gly Ala Phe Gly Lys Val Val Glu Cys Ile Asp
                 170                 175                 180

 His Lys Ala Gly Gly Arg His Val Ala Val Lys Ile Val Lys Asn
                 185                 190                 195

 Val Asp Arg Tyr Cys Glu Ala Ala Arg Ser Glu Ile Gln Val Leu
                 200                 205                 210

 Glu His Leu Asn Thr Thr Asp Pro Asn Ser Thr Phe Arg Cys Val
                 215                 220                 225

 Gln Met Leu Glu Trp Phe Glu His His Gly His Ile Cys Ile Val
                 230                 235                 240

 Phe Glu Leu Leu Gly Leu Ser Thr Tyr Asp Phe Ile Lys Glu Asn
                 245                 250                 255

 Gly Phe Leu Pro Phe Arg Leu Asp His Ile Arg Lys Met Ala Tyr
                 260                 265                 270

 Gln Ile Cys Lys Ser Val Asn Phe Leu His Ser Asn Lys Leu Thr
                 275                 280                 285

 His Thr Asp Leu Lys Pro Glu Asn Ile Leu Phe Val Gln Ser Asp
                 290                 295                 300

 Tyr Thr Glu Ala Tyr Asn Pro Lys Ile Lys Arg Asp Glu Arg Thr
                 305                 310                 315

 Leu Ile Asn Pro Asp Ile Lys Val Val Asp Phe Gly Ser Ala Thr
                 320                 325                 330

 Tyr Asp Asp Glu His His Ser Thr Leu Val Ser Thr Arg His Tyr
                 335                 340                 345

 Arg Ala Pro Glu Val Ile Leu Ala Leu Gly Trp Ser Gln Pro Cys
                 350                 355                 360

 Asp Val Trp Ser Ile Gly Cys Ile Leu Ile Glu Tyr Tyr Leu Gly
                 365                 370                 375

 Phe Thr Val Phe Pro Thr His Asp Ser Lys Glu His Leu Ala Met
                 380                 385                 390

 Met Glu Arg Ile Leu Gly Pro Leu Pro Lys His Met Ile Gln Lys
                 395                 400                 405

 Thr Arg Lys Arg Lys Tyr Phe His His Asp Arg Leu Asp Trp Asp
                 410                 415                 420

 Glu His Ser Ser Ala Gly Arg Tyr Val Ser Arg Ala Cys Lys Pro
                 425                 430                 435

 Leu Lys Glu Phe Met Leu Ser Gln Asp Val Glu His Glu Arg Leu
                 440                 445                 450

 Phe Asp Leu Ile Gln Lys Met Leu Glu Tyr Asp Pro Ala Lys Arg
                 455                 460                 465

 Ile Thr Leu Arg Glu Ala Leu Lys His Pro Phe Phe Asp Leu Leu
                 470                 475                 480

 Lys Lys Ser Ile


<210> 2922
<211> 2024
<212> DNA
<213> Homo sapien

<400> 2922
 gcagtgactc tgggaaatcc ttcattaatc attcacacct tcagggacat 50

 ttaagaactc acaatggaga aagtctccat gaatggaagg aatgtgggag 100

 aggctttatt cactccacag accttgctgt gcgtatacaa actcacaggt 150

 cagaaaaacc ctacaaatgt aaggaatgtg gaaaaggatt tagatattct 200

 gcatacctta atattcacat gggaacccac actggagaca atccctatga 250

 gtgtaaggag tgtgggaaag ccttcaccag gtcttgtcaa cttactcagc 300

 acagaaaaac tcacactgga gagaaacctt ataaatgtaa ggattgtggg 350

 agagccttca ctgtttcctc ttgcttaagt caacatatga aaatccatgt 400

 gggtgagaag ccttatgaat gcaaggaatg tgggatagcc ttcactagat 450

 cttctcaact tactgaacat ttaaaaactc acactgcaaa ggatcccttt 500

 gaatgtaaga tatgtggaaa atcctttaga aattcctcat gcctcagtga 550

 tcactttcga attcacactg gaataaaacc ctataaatgt aaggattgtg 600

 ggaaagcctt cactcagaac tcagacctta ctaagcatgc acgaactcac 650

 agtggagaga ggccctatga atgtaaggaa tgtggaaagg cctttgccag 700

 atcctctcgc cttagtgaac atacaaggac tcacactgga gagaagcctt 750

 ttgaatgtgt caaatgtggg aaagcctttg ctatttcttc aaatcttagt 800

 ggacatttga gaattcacac tggagagaag ccctttgagt gcctggaatg 850

 tggtaaagca tttacgcatt cctccagtct taataatcac atgcggaccc 900

 acagcgccaa aaaaaccatt cacgtgtatg gaatgtggca aagcctttaa 950

 gtttcccacg tgtgttaacc ttcacatgcg gatccacact ggagaaaaac 1000

 cctacaaatg taaacagtgt gggaaatcct tcagttactc caattcgttt 1050

 cagttacatg aacgaactca cactggagag aaaccctatg aatgtaagga 1100

 gtgcgggaaa gccttcagtt cttccagttc cttttgaaat catgaaagaa 1150

 ggcatgcgga tgagagactg tcagcataag gaatgtggga aaacctaaag 1200

 gtgtccctgt tctctctgaa gacatgaaaa ctcactgggg agaaacccta 1250

 tgaatgtaaa aatgtggaag caactttgta tctcaggtct taatgaacac 1300

 atatgaattc acagtggaga agaccctgca tcaggtaatg tggaaatgac 1350

 tttgctgaat tctcaagcct taccaaacac atcagaaatc tcactggaga 1400

 gaaaccgtat gaatgtagag aatctgggaa tacctttctg aatcccacaa 1450

 accttaatgt gtgtatgtga actcacattg gagagaaacc ctgcaattta 1500

 aatggtatgg tctggatgat gccccactcc atatttgtaa gccctaagtc 1550

 ctagttcctt acactataac tgtatttgga catagggttt tcaaacaggt 1600

 gagtaacttc aaatgaggtt gttgggttcg atccctaatc tgacatcact 1650

 ggtgtcccta taagggaaac tgaaggaagg atacacatgg agaagactgt 1700

 gtggatccac cagaagatgg ccatctacaa gccaaggaca gagacctgga 1750

 acagatgctt tcattatggc ctccagagga aaccaaccct gtctccacct 1800

 tgatattgca cttccaggct ccagaactgt gaggcaataa atttctcttg 1850

 gttaaatcat tcagtctgtt attttgtaca gcaaccctag gaaactaata 1900

 ctgtgaggaa cttgggaaaa gctttagatc aagcttgtcc aacccgcagg 1950

 ccaggatggc tttgaatgca gaccaacaca aatttttaag ctttcttcaa 2000

 acataataaa atttttttgt gatt 2024

<210> 2923
<211> 243
<212> PRT
<213> Homo sapien

<400> 2923
 Met Gly Thr His Thr Gly Asp Asn Pro Tyr Glu Cys Lys Glu Cys
   1               5                  10                  15

 Gly Lys Ala Phe Thr Arg Ser Cys Gln Leu Thr Gln His Arg Lys
                  20                  25                  30

 Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Asp Cys Gly Arg
                  35                  40                  45

 Ala Phe Thr Val Ser Ser Cys Leu Ser Gln His Met Lys Ile His
                  50                  55                  60

 Val Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Ile Ala Phe
                  65                  70                  75

 Thr Arg Ser Ser Gln Leu Thr Glu His Leu Lys Thr His Thr Ala
                  80                  85                  90

 Lys Asp Pro Phe Glu Cys Lys Ile Cys Gly Lys Ser Phe Arg Asn
                  95                 100                 105

 Ser Ser Cys Leu Ser Asp His Phe Arg Ile His Thr Gly Ile Lys
                 110                 115                 120

 Pro Tyr Lys Cys Lys Asp Cys Gly Lys Ala Phe Thr Gln Asn Ser
                 125                 130                 135

 Asp Leu Thr Lys His Ala Arg Thr His Ser Gly Glu Arg Pro Tyr
                 140                 145                 150

 Glu Cys Lys Glu Cys Gly Lys Ala Phe Ala Arg Ser Ser Arg Leu
                 155                 160                 165

 Ser Glu His Thr Arg Thr His Thr Gly Glu Lys Pro Phe Glu Cys
                 170                 175                 180

 Val Lys Cys Gly Lys Ala Phe Ala Ile Ser Ser Asn Leu Ser Gly
                 185                 190                 195

 His Leu Arg Ile His Thr Gly Glu Lys Pro Phe Glu Cys Leu Glu
                 200                 205                 210

 Cys Gly Lys Ala Phe Thr His Ser Ser Ser Leu Asn Asn His Met
                 215                 220                 225

 Arg Thr His Ser Ala Lys Lys Thr Ile His Val Tyr Gly Met Trp
                 230                 235                 240

 Gln Ser Leu


<210> 2924
<211> 6720
<212> DNA
<213> Homo sapien

<400> 2924
 tcaaagtaaa ggtattctaa agatttcagc tgtccctgaa ctaactgatg 50

 tgaatactgg aaaaccagta tctctctcta gttcttattt tcacagagag 100

 aaatcgaata ttttcagtcc acaggaattg ccaggtagtc atgtaactga 150

 agatgtgctg aaggtttcaa caattcctgg accagctggc cagaaaacag 200

 tattaccaac agctcttcct agttcctttt cacatcgaga gaaaccagat 250

 attttctatc aaaaggattt gccagataga catctaactg aagatgctct 300

 aaagatctca agtgctcttg ggcaagctga tcaaattacc ggattacaaa 350

 cagttccctc tggtacttac tcacatggtg agaatcacaa gcttgtttca 400

 gaacatgtcc aaaggctaat agataatttg aattcttctg actccagtgt 450

 tagctcaaat aatgtgcttt taaattctca ggctgatgac agagttgtaa 500

 taaataaacc agaatctgca ggttttagag atgttggctc tgaagaaatc 550

 caggatgcag aaaatagtgc taaaactctt aaggaaattc ggacactttt 600

 gatggaggca gaaaatatgg cactgaaacg atgcaatttt cctgctcccc 650

 ttgcccgttt cagagatatt agtgatattt catttataca atctaagaag 700

 gtggtttgct tcaaagaacc ctcttccacg ggtgtatcta atggtgattt 750

 gcttcacaga cagccattca cagaggaaag cccaagcagc aggtgcatac 800

 agaaggatat tggcacacag acgaatttga aatgccggag aggcattgaa 850

 aattgggagt ttattagttc aactacagtt agaagtcctc tacaggaagc 900

 agagagcaaa gtcagtatgg cattagaaga aactcttagg caatatcaag 950

 cagccaaatc tgtaatgagg tctgaacctg aagggtgtag tggaaccatt 1000

 gggaataaaa ttattatccc tatgatgact gtcataaaaa gtgattcaag 1050

 tagtgatgcc agtgatggaa atggttcctg ctcgtgggac agtaatttac 1100

 cagagtcttt ggaatcagtt tctgatgttc ttctaaactt ctttccatat 1150

 gtttcaccca agacaagtat aacagatagc agggaggaag agggtgtgtc 1200

 agagagtgag gatggtggtg gtagcagtgt agattcactg gctgcacatg 1250

 tgaaaaacct tctgcaatgt gaatcctcac tgaatcatgc taaagaaata 1300

 ctcagaaatg cagaggaaga ggaaagccgg gtacgagcac atgcctggaa 1350

 tatgaagttc aatttagcac atgattgtgg atactccatt tcagaattaa 1400

 atgaagatga caggaggaaa gtagaagaga tcaaggcaga gttatttggt 1450

 catggaagaa caactgactt gtccaagggt ttacagagtc cacggggaat 1500

 gggatgcaag ccagaagctg tatgtagtca cattattatt gagagccatg 1550

 aaaagggatg tttccggact ctaacttctg aacatccaca actagataga 1600

 cacccttgtg ctttcagatc tgctggaccc tcagaaatga ccagaggacg 1650

 gcagaaccca tcatcatgca gagccaagca tgtcaacctt tctgcatcct 1700

 tagaccagaa caactcccat ttcaaagttt ggaattcctt gcagttaaaa 1750

 agtcattccc catttcagaa ctttatacct gatgaattca aaatcagcaa 1800

 aggtcttcga atgccattcg atgaaaagat ggacccttgg ctgtcagaat 1850

 tagtagaacc tgcttttgtg ccacctaaag aagtggattt tcattcttca 1900

 tcacaaatgc cgtccccaga acccatgaaa aagtttacta cctccatcac 1950

 tttttcatct caccgacatt ctaaatgcat ttccaattcc tctgttgtta 2000

 aggttggtgt tactgaaggt agccagtgta ctggagcatc tgtgggggta 2050

 tttaattctc atttcactga agaacaaaat cctcccagag atcttaaaca 2100

 gaaaacctct tccccttcat catttaaaat gcatagtaat tcacaagata 2150

 aagaagtgac tattttagca gaaggtagaa ggcaaagcca aaaattacct 2200

 gttgattttg agcgttcttt tcaagaagaa aaacccttag aaagatcaga 2250

 ttttacaggc agtcattctg agcccagtac cagggcaaat tgtagcaatt 2300

 tcaaggaaat tcagatttct gataaccata cccttattag catgggcaga 2350

 ccaagttcca ccctaggagt aaacagatcg agttccagac taggagtaaa 2400

 agagaagaat gtaactataa ctccagatct tccttcttgc atttttcttg 2450

 aacaacgaga gctctttgaa caaagcaaag ccccacgtgc agatgaccat 2500

 gtgaggaaac accattctcc ctctcctcaa catcaggatt atgtagctcc 2550

 agaccttcct tcttgcattt ttcttgaaca acgagaactc tttgaacagt 2600

 gcaaagcccc atatgtagat catcaaatga gagaaaacca ttctcccctt 2650

 cctcaaggtc aggattctat agcttcagac cttccgtctc ccatttctct 2700

 tgaacaatgc caaagcaaag cgccaggtgt agatgaccaa atgaataaac 2750

 accattttcc ccttcctcaa ggtcaggatt gtgtagtgga aaagaataat 2800

 caacataagc ctaaatcaca catttctaat ataaatgttg aagccaagtt 2850

 caatactgtg gtctcccagt cagccccaaa tcactgtaca ttagcagcat 2900

 ctgcatctac tcctccttca aatagaaaag cactttcttg tgttcatata 2950

 actctttgtc ccaagacttc ttccaagttg gatagtggaa ctttagatga 3000

 aagattccat tcattggatg ctgcttctaa agcgaggatg aatagtgagt 3050

 ttaactttga cttacatact gtatcttcga gatcactgga accaacctcc 3100

 aaattattga ccagtaaacc tgtagcacag gatcaagaat ctttaggttt 3150

 tctaggacct aaatcttcac tggatttcca agtcgtacag ccttctcttc 3200

 cagacagtaa cactattact caggacttga aaaccatacc ttctcagaat 3250

 agccagatag taacctccag gcaaatacaa gtgaacattt cagatttcga 3300

 aggacattcc aatccagagg ggaccccagt atttgcagat cgattaccag 3350

 agaagatgaa gaccccactt tctgctttct ctgaaaaatt gtcatctgat 3400

 gcagtcactc agataacaac agaaagtcca gaaaagaccc tattttcatc 3450

 tgagattttt attaatgctg aagatcgtgg acatgaaatt atagagcctg 3500

 gtaaccagaa gctacgcaaa gctcctgtca agtttgcctc atcatcttca 3550

 gtccaacagg ttactttttc tcgcggcaca gatggccagc ctttattatt 3600

 gccatataag ccttctggta gtaccaagat gtattatgtt ccacaattaa 3650

 gacaaattcc tccatctccg gattccaaat cagataccac cgttgaaagc 3700

 tcccattcag gatccaatga tgccattgct ccagacttcc cagctcaggt 3750

 gctaggcaca agagatgatg acctctcagc cactgttaac attaaacata 3800

 aagaaggaat ctacagtaag agggtagtga ctaaggcatc cttgccagtg 3850

 ggagaaaaac ccttgcagaa tgaaaatgca gatgcctcag ttcaagtgct 3900

 aatcactggg gatgagaacc tctcagacaa aaaacagcaa gagattcaca 3950

 gtacaagggc agtgactgag gctgcccagg ctaaagaaaa agaatctttg 4000

 cagaaagata ctgcagattc cagtgctgct gctgctgcag agcactcagc 4050

 tcaagtagga gacccagaaa tgaagaactt gccagacact aaagccatta 4100

 cacagaaaga ggagatccat aggaagaaga cagttcccga ggaagcctgg 4150

 ccaaacaata aagaatccct acagatcaat attgaagagt ccgaatgtca 4200

 ttcagaattt gaaaatacta cccgttctgt cttcaggtca gcaaagtttt 4250

 acattcatca tcccgtacac ctaccaagtg atcaagatat ttgccatgaa 4300

 tctttgggaa agagtgtttt catgagacat tcttggaaag atttctttca 4350

 gcatcatcca gacaaacata gagaacacat gtgtcttcct cttccttatc 4400

 aaaacatgga caagactaag acagattata ccagaataaa gagcctcagc 4450

 atcaatgtga atttgggaaa caaagaagtg atggatacta ctaaaagtca 4500

 agttagagat tatccaaaac ataatggaca aattagtgat ccacaaaggg 4550

 atcagaaggt caccccagag caaacaactc agcacactgt gagtttgaat 4600

 gaactgtgga acaagtatcg ggagcgacag aggcaacaga gacagcctga 4650

 gttgggtgac aggaaagaac tgtccttggt ggaccgactt gatcggttgg 4700

 ctaaaattct tcagaatcca atcacacatt ctctccaggt ctcagaaagt 4750

 acacatgatg atagcagagg ggaacgaagt gtgaaggaat ggagtggtag 4800

 acaacagcag agaaataagc ttcagaaaaa gaagcggttt aaaagcctag 4850

 agaaaagcca taaaaataca ggcgagctta aaaaaagcaa ggtgctttct 4900

 catcatcgag ctgggaggtc taatcaaatt aaaattgaac agattaaatt 4950

 tgataaatat attctgagta aacagccagg ttttaattat ataagcaaca 5000

 cttcttcgga ttgtcggccc tcagaggaga gtgagctgct cacagatact 5050

 accaccaaca tcctttccgg caccacttct actgtcgaat cagatatatt 5100

 gacccaaaca gatagagagg tggctctgca cgaaaggagt agctctgttt 5150

 ccactattga cactgcccgg ctgattcaag cttttggcca tgaaagagta 5200

 tgcttgtcac ccagacgaat taaattatat agcagcatca ccaaccaaca 5250

 gaggagatac cttgagaagc ggagcaaaca cagcaagaaa gtgctgaata 5300

 caggtcatcc cctagtgact tctgagcaca ccagaaggag acacatccag 5350

 gtagcaaacc atgtgatttc ttctgactct atttcctctt ctgccagtag 5400

 tttcctgagc tcaaactcta ctttttgcaa caagcagaat gtacacatgt 5450

 taaacaaggg catacaagca ggtaacttgg agattgtgaa cggtgccaaa 5500

 aaacacactc gagatgttgg gataactttc ccaactccaa gttccagcga 5550

 ggctaaattg gaagagaaca gtgatgtgac ttcttggtca gaagaaaaac 5600

 gtgaagagaa aatgctcttt accggttatc ctgaggacag aaagttaaaa 5650

 aagaacaaga agaattccca tgaaggagtt tcctggtttg ttcctgtgga 5700

 aaatgtggag tctagatcaa agaaggaaaa cgtgcctaac acttgtggcc 5750

 ctggcatctc ctggtttgaa ccaataacca agaccagacc ctggagggag 5800

 ccactgcggg agcagaactg tcaggggcag cacctggacg gtcggggcta 5850

 cctggcaggc ccaggcagag aggctggcag agacctactg aagccatttg 5900

 tgagagcaac ccttcaggaa tcgcttcagt ttcacagacc tgacttcatc 5950

 tcccgctctg gggagcggat aaagcgcctg aagttaatag tccaggagag 6000

 gaagctgcag agcatgttac agaccgagcg ggatgcacta ttcaacattg 6050

 acagggaacg gcagggccac cagaatcgca tgtgcccgct gcccaagaga 6100

 gtcttcctgg ctatccagaa gaacaagcct atcagcaaga aggaaatgat 6150

 tcagaggtcc aaacggtaag accaagaaaa caagagtacg tatacaagtg 6200

 taaaccaggc caccaagtgg tcgggagctc tggcttgcac ccagaataaa 6250

 tgtattatac tcaagtttaa acattatgag aaagttgtga gagtcatttc 6300

 tcacttatgg cactgaaaaa aaaaaaagca catcatggta tgaatgactc 6350

 atatgcaaaa gatgaaaaac ttctcactaa tttgcatgtc ttaggctcct 6400

 ctttattaga aacctaaatg taaataaaga atattttagg ccaggtacgg 6450

 tggctcatgc ctgtaatccc agcacttagg gaggccgagg tgtgcagatc 6500

 acatgaggtt aggagttcga gaccagcctg gccaacatgg tgaaactcca 6550

 tctctactca aaatacaaaa attagctggg tgtggaggca cacgcctgta 6600

 atcccagcta ctcagtaggc tgagccggga ggatctcttg aacctgggag 6650

 gcagaggttg cagtgagctt agatggtgcc actgtactcc agtctgggcg 6700

 acagaacgag actccatctc 6720

<210> 2925
<211> 2924
<212> DNA
<213> Homo sapien

<400> 2925
 tatttttatt gaggctaata tattatcctt tggtgccatg agtggatgaa 50

 gaaactttca gaaggctaaa cgagtggata caagaaactt aggcaaatta 100

 ttacaccaca ggggtgtgag aaataatgaa tattctctac taggtttcag 150

 caaacataat ccaagctgat caatttagga cacttccact gaagagacgt 200

 gaagtgtacg ttcaactgaa gtgtcattgt aattgtgtgc cttctcagtt 250

 attgggcaag ttaaagagca tgatgaatgt ttgtactata atggtgtaaa 300

 tccttctgat ttcttgcatg gaagacatgt ggcatcatgt agaacctgct 350

 ttgacattga ttctcaattg tatgagttgc tcctctgatt ttagatcaca 400

 tttgtcaata tcaatgtgga tatgccaagt gatgaggaca cggttttatt 450

 ttagttttag acatatgaca aatcatgcca tgtttgaaat tgtaagtata 500

 ttttgtgaag cctgtattca cctttttcag tgtatttctg tcatattcca 550

 gtcccgagtc acaaagtaga aaacatcaaa gcctatacta atacaggcag 600

 gaagatacat cttgatgcca acagtgcagg aatgtatgga taactttatc 650

 atatttacat atgagtgatt atgtatccct tttgcttttc agtgtcttct 700

 cagaaacaac cagccttgaa ggctacaagt gacaagaaag attctgtttc 750

 gaatataccc acagaaataa aggatggaca acaatctgga acagtgtctt 800

 ctcagaaaca accggcctgg aaggctacaa gtgtcaagaa agattctgtt 850

 tcgaatatag ccacagaaat aaaggatgga caaatacgtg ggacagtgtc 900

 tcctcagaaa caatcggccc agaaggttat atttaaaaag aaagtttctc 950

 ttttgaatat tgccacaaga ataacaggcg gttggaaatc tggaacagag 1000

 tatcctgaga atctgcccac cttgaaggct acaattgaaa ataaaaattc 1050

 tgttctgaat acagccacca aaatgaagga tgtacaaaca tccacaccag 1100

 aacaagactt agaaatggca tcagagggag agcaaaagag gcttgaagaa 1150

 tatgaaaata accagccaca ggtgaaaaac caaatacatt ctagggatga 1200

 ccttgatgac ataattcagt catctcaaac agtctcagag gacggtgact 1250

 cgctttgctg taattgtaag aatgtcatat tactcattga tcaacatgaa 1300

 atgaagtgta aagattgtgt tcacctattg aaaattaaaa atacattttg 1350

 tttatggaaa agattaataa aacttaaaga taaccactgt gagcaactta 1400

 gagtaaaaat tcgaaaactg aaaaataagg ctagtgtact acaaaagaga 1450

 atatctgaaa aagaagaaat aaaatcgcag ttaaagcatg aaatacttga 1500

 attggaaaaa gaactctgta gtttgagatt tgccatacag caagaaaaaa 1550

 agaaaagaag aaatgttgaa gagttgcacc aaaaagttag ggaaaagtta 1600

 agaataacag aagagcaata taggatagaa gctgatgtga caaaaccaat 1650

 taaaccggct ctcaaatcag cagaggtgga attgaagaca ggaggaaata 1700

 attcaaatca ggtttctgaa actgatgaaa aagaagacct gctgcatgaa 1750

 aaccgcttga tgcaagatga aattgccagg ctcaggctgg aaaaagacac 1800

 aataaaaaac caaaacctgg aaaagaaata cttaaaagac tttgaaattg 1850

 tgaaaagaaa gcatgaagac cttcaaaagg ctctaaaacg gaatggggaa 1900

 acattagcaa aaacgatagc ctgttatagt ggacagcttg ctgctctgac 1950

 agatgaaaac acaacgctcc gttccaaact ggagaagcaa agagagagca 2000

 ggcaaagact ggaaacagaa atgcaatcat accattgtag actgaatgct 2050

 gctcgatgtg atcatgatca aagtcactca tcaaaaagag accaagagct 2100

 tgctttccag ggcacagtag ataaatgtcg tcacttacag gaaaatttga 2150

 attctcatgt tctgattctt tctctgcaac tttctaaagc tgagagtaag 2200

 tccagagtcc tcaaaactga gctccattac acaggagagg ctctgaaaga 2250

 aaaggctttg gtttttgaac acgtgcaaag tgagctaaag caaaaacaga 2300

 gtcaaatgaa ggacattgaa aaaatgtaca aaagtggata caatacaatg 2350

 gaaaaatgca tagaaaaaca ggaaagattt tgtcaactaa aaaaacaaaa 2400

 tatgttgctt caacagcaac tggatgatgc tcgcaacaaa gctgacaatc 2450

 aagaaaaagc aatacttaat attcaagcca gatgtgatgc tagagtacaa 2500

 aaccttcaag ctgagtgcag aaagcaccgt cttttactag aagaagacaa 2550

 taaaatgttg gtcaatgaac tgactcattc gaaagaaaaa gaatgccaat 2600

 atgaaaaaga gaaagcagaa agagaagtag ctgtgagaca gcttcaacaa 2650

 aaacgagatg atgtcttaaa caaaggatca gcaacaaaag ctctgctgga 2700

 tgcttcatcg cgtcactgca cctatttaga aaatgggatg caggattcaa 2750

 ggaagaaatt agaccagatg agaagtcaag tatgtatgca actttgcaca 2800

 ccaacaactg ttaatctgta gctagttaac taatataaag tgttttgggg 2850

 tactaatttt agtggatggc tttcttttgt atttttatga taattaatgt 2900

 tattaaaatt ttatagtgga tggc 2924

<210> 2926
<211> 4732
<212> DNA
<213> Homo sapien

<400> 2926
 gatgcccccg ccagggggga tgcccggcac cgtgcgtccg cggaggccaa 50

 gatgcagcgg ccaggggccg gcagcctgcg aggggaggca gcttccgccg 100

 gggccgggct gctgcacagt ctgagcggcc gggactgcgc gcttcagagc 150

 ctggagcatc ccagtcgctg gggccgagac gccgccgccg ccgccgttcc 200

 cgctttctcc cgcgagccgg gccagtagct ttgctagctg gccttcccgt 250

 ggaggcgttt tccagcccca gcgcggggag acatgcctga atttgggagc 300

 gatgtgactc tcagcctccc acttcacccg gggacgcagg cttgctgaag 350

 cccgagacag gagggggacc atgggaggga cgcaagtcaa atgcctgact 400

 tcacccagtc caatccacag tgcaaagagc gagtccatta taacccagtc 450

 agaagagaag gcagattttg tgattattcc cgctgaagga atagagaaca 500

 gaacagaagg gacagattct ccattatctc gagactggcg gccagggagc 550

 cctggaacct atctggagac ctcatgggaa gaacagctgt tggaacaaca 600

 agaatattta gaaaaagaaa tggaggaagc aaagaaaatg atatcaggac 650

 tacaggcctt actgctcaat ggatccttac ctgaagatga acaggagagg 700

 cccttggccc tctgtgaacc aggtgtcaat cccgaggaac aactgattat 750

 aatccaaagt cgtctggatc agagtatgga ggagaatcag gacttaaaga 800

 aggaactgct gaaatgtaaa caagaagcca gaaacttaca ggggataaag 850

 gatgccttgc agcagagatt gactcagcag gacacatctg ttcttcagct 900

 caaacaagag ctactgaggg caaatatgga caaagatgag ctgcacaacc 950

 agaatgtgga tctgcagagg aagctagatg agaggaaccg gctcttggga 1000

 gaatataaaa aagagctggg gcagaaggat cgccttcttc agcagcacca 1050

 ggccaagtta gaagaagcac tccggaaact ctctgatgtc agttaccacc 1100

 aggtggatct agagcgagag ctagaacaca aagatgtcct cttggctcac 1150

 tgtatgaaaa gagaggcaga tgaggcgacc aactacaaca gtcacaactc 1200

 tcaaagcaat ggttttctcc ttccaacggc aggaaaagga gctacttcag 1250

 tcagcaacag agggaccagc gacctgcagc ttgttcgaga tgctctccgc 1300

 agcctgcgca acagcttcag tggccacgat cctcagcacc acactattga 1350

 cagcttggag cagggcattt ctagcctcat ggagcgcctg catgttatgg 1400

 agacgcagaa gaaacaagaa agaaaggttc gggtcaagtc acccagaact 1450

 caagtaggta gtgaataccg ggagtcctgg ccccctaact caaagttgcc 1500

 tcactcacag agctctccaa ctgtcagcag cacctgtact aaagtgctct 1550

 atttcactga ccggtcactt acgcccttca tggtcaatat accaaagagg 1600

 ttggaggagg tgacgttaaa ggattttaaa gcagctattg atcgggaagg 1650

 aaatcaccgg tatcacttca aagcactgga tcctgagttt ggcactgtca 1700

 aagaggagat tttccatgat gatgatgcca tccctggatg ggaagggaaa 1750

 attgtagctt gggtggaaga agaccatgga gagaattaat gccaagtatc 1800

 agattgaggg cttatggaac ctggtcactc cctggctgct tcactcagga 1850

 aagggaacta aaaccagaat acactaagaa gtttctagtt tgtgtgccaa 1900

 aacagaagct tctccaagca tgatggccac aggtcagtcc tctttctgtg 1950

 cctggcatat ctggtactta aaattctgtc caaatgtaga ccatgggttc 2000

 atctggagtt ccttgtccgt gggaacacag tgttctattc tactctgagg 2050

 acaacaaacc gaaggcctta aacgatgggg atggatgatc ccgcctctgt 2100

 aggggcatgg ctgctattat ctggaaatta ggaattggat gcatcattcc 2150

 tgtgtgttac agtattattt taattggcct caatggttgc agcaatcaga 2200

 gtcccagcgt ttgtactcac agacaaggca aaggtaccag cttttctgtt 2250

 tctttgaacc tactgcaaac caagaataac tcatgaggtg gtaccaaaga 2300

 tgaaagccca gacttcagta atcttttgaa ccagacgtgg atggtgctga 2350

 attgttgctt ggatggaaaa agggctgccc atgttgtgct acactatgct 2400

 aaaactgtaa tttagtaaga ccttgggctg cctcttctgt cttaactggt 2450

 tctgcagctt gtccttttgc ccacataggg cctatttcat gtactgttag 2500

 ttttctctgg ggactcttta actttagagc catttctttt tcttcaaact 2550

 gatgaacttt tgtttgaaag gcataaggag tgaaaagctc cttgaaaatc 2600

 caggcgggta tggaaaggtg ctgctaccca tatctttttg actttctttg 2650

 tttcatgact ttaactcatg gcatctcctt tgtagtaaaa ggagacagac 2700

 cattaatttc agcatttctt tgtgatttat aagtactgag catgaagtac 2750

 ttgtctgccc ctcatttcaa ggccagagtt attttctatt tatgtattag 2800

 tctaggctga tcttttaggg cacaatagaa accatggggc gtggagcatg 2850

 agttgtgaat ggcagggatc attctgggta aaaaaaacct agaatcattt 2900

 ctgatgtgca acattgtcaa gtgaagaagc taacagttca actaccgaga 2950

 ttatttgata acctgggttt tctcattcat ccatcaagca ccatcaacca 3000

 gtcagccatt attatttata tatgtattac caaaagcagt ctatctgcct 3050

 gtgacctcca atgtacactg ccaaacacaa gagtaggaca catctgttct 3100

 gggttcttga cctatctgtc tccaattcat ctcccctttt cagccatttc 3150

 aacaaactac tctttggagc tctgagatga catcttgttg ttttatatag 3200

 atgtatcttt taaaaatagt tcacgtttgg agaattcttt tgtactcatt 3250

 tgctttttgt ctgagaacca tgtctatttt tataactgga gtgtgagttc 3300

 tgtatcttct cacattctgt atactgtatc cattttctag agaacccagt 3350

 agcttttata cagtctcttc ttaccacccc ttgtggtttc agaacaagct 3400

 ttattttatt acgagtatat taatgacaac taattcctgt tccaattcta 3450

 cctgttttag ttgtgaaggt agttttgtgt aatccagttg attgctcctc 3500

 tggcagagag aaggagctca aaagatactt gatgtctttc atgtaagttt 3550

 acctggtctt ttcctattga agaatttttc atcagaaacg actgggaaag 3600

 tttgggaaag tcagcaaaag aaagaatgca tttcgaaagc aaacagaaga 3650

 aaaaagtata ttctcacagt ttttccccag gaagtctgga gaaaaagtcc 3700

 tcatgtcacc aatttctctg ttgcatgaat tttagtgttt tgctataaga 3750

 cagcatgagg gctatcaggc caaaattcat tattgtattt ccaatacagt 3800

 ttgtcttgaa tgtctgtctc ttaaaccagt ttttacttgt cagttttctc 3850

 tcagcaaaca gtcttactat tatgtggaat ttaacttttc agagaaaatt 3900

 tccaaagtcc tctaccttat ttggctttta tctgtgtctt ttggaaaagg 3950

 agctgcatgg cctcagtgcc tccataaaaa gcttaagttg agttcatggg 4000

 agaacattaa gatcgttttt tttccctttt agctcggtaa tctcatgtac 4050

 cacaggtaat gaccaagcat ctctgctaga ggatgtaact ctcataactc 4100

 ctgtgtaaaa tgaggatcct gttggtgatc ctcattccag tttccaaagc 4150

 gagaggagcc ttctgagcag aagtatgcaa gactgattct gtttggaaca 4200

 gtttcctatt tggctgcatt ctaggaggcc tcctgactta ttcatagtat 4250

 tgtcgcctgg tggcattggt gtggggtagc ttgtcctgct acttgctaaa 4300

 gttctctttc tttgagaaaa ctgaggaacc agaatgctta gagttcataa 4350

 aataatctct aaaccatgtt aggttaaaac aaaatgacca tctcacaaaa 4400

 acgagtttag ttgaatgctc aattccttac aaaatcttca tttaaggctg 4450

 agtgtggtgg ctcatgcctg taattccagc actttgggag gccgaggcag 4500

 gaagactgct tgagcccagg agttcaagac cagcctgggc aacgtaggaa 4550

 gactccgtct ctacatagaa attttattat aaaagtagct ggggatggtg 4600

 gcacacacct gtagtcccag ctactcagga ggttgaggtg ggaagattgc 4650

 ttgagcccag gagtttgagg ttgcagtgag ctgatcatgc cactgcactc 4700

 tagcctaggc tacagagcag gaccccatct cc 4732

<210> 2927
<211> 493
<212> PRT
<213> Homo sapien

<400> 2927
 Leu Ser Ala Ser His Phe Thr Arg Gly Arg Arg Leu Ala Glu Ala
   1               5                  10                  15

 Arg Asp Arg Arg Gly Thr Met Gly Gly Thr Gln Val Lys Cys Leu
                  20                  25                  30

 Thr Ser Pro Ser Pro Ile His Ser Ala Lys Ser Glu Ser Ile Ile
                  35                  40                  45

 Thr Gln Ser Glu Glu Lys Ala Asp Phe Val Ile Ile Pro Ala Glu
                  50                  55                  60

 Gly Ile Glu Asn Arg Thr Glu Gly Thr Asp Ser Pro Leu Ser Arg
                  65                  70                  75

 Asp Trp Arg Pro Gly Ser Pro Gly Thr Tyr Leu Glu Thr Ser Trp
                  80                  85                  90

 Glu Glu Gln Leu Leu Glu Gln Gln Glu Tyr Leu Glu Lys Glu Met
                  95                 100                 105

 Glu Glu Ala Lys Lys Met Ile Ser Gly Leu Gln Ala Leu Leu Leu
                 110                 115                 120

 Asn Gly Ser Leu Pro Glu Asp Glu Gln Glu Arg Pro Leu Ala Leu
                 125                 130                 135

 Cys Glu Pro Gly Val Asn Pro Glu Glu Gln Leu Ile Ile Ile Gln
                 140                 145                 150

 Ser Arg Leu Asp Gln Ser Met Glu Glu Asn Gln Asp Leu Lys Lys
                 155                 160                 165

 Glu Leu Leu Lys Cys Lys Gln Glu Ala Arg Asn Leu Gln Gly Ile
                 170                 175                 180

 Lys Asp Ala Leu Gln Gln Arg Leu Thr Gln Gln Asp Thr Ser Val
                 185                 190                 195

 Leu Gln Leu Lys Gln Glu Leu Leu Arg Ala Asn Met Asp Lys Asp
                 200                 205                 210

 Glu Leu His Asn Gln Asn Val Asp Leu Gln Arg Lys Leu Asp Glu
                 215                 220                 225

 Arg Asn Arg Leu Leu Gly Glu Tyr Lys Lys Glu Leu Gly Gln Lys
                 230                 235                 240

 Asp Arg Leu Leu Gln Gln His Gln Ala Lys Leu Glu Glu Ala Leu
                 245                 250                 255

 Arg Lys Leu Ser Asp Val Ser Tyr His Gln Val Asp Leu Glu Arg
                 260                 265                 270

 Glu Leu Glu His Lys Asp Val Leu Leu Ala His Cys Met Lys Arg
                 275                 280                 285

 Glu Ala Asp Glu Ala Thr Asn Tyr Asn Ser His Asn Ser Gln Ser
                 290                 295                 300

 Asn Gly Phe Leu Leu Pro Thr Ala Gly Lys Gly Ala Thr Ser Val
                 305                 310                 315

 Ser Asn Arg Gly Thr Ser Asp Leu Gln Leu Val Arg Asp Ala Leu
                 320                 325                 330

 Arg Ser Leu Arg Asn Ser Phe Ser Gly His Asp Pro Gln His His
                 335                 340                 345

 Thr Ile Asp Ser Leu Glu Gln Gly Ile Ser Ser Leu Met Glu Arg
                 350                 355                 360

 Leu His Val Met Glu Thr Gln Lys Lys Gln Glu Arg Lys Val Arg
                 365                 370                 375

 Val Lys Ser Pro Arg Thr Gln Val Gly Ser Glu Tyr Arg Glu Ser
                 380                 385                 390

 Trp Pro Pro Asn Ser Lys Leu Pro His Ser Gln Ser Ser Pro Thr
                 395                 400                 405

 Val Ser Ser Thr Cys Thr Lys Val Leu Tyr Phe Thr Asp Arg Ser
                 410                 415                 420

 Leu Thr Pro Phe Met Val Asn Ile Pro Lys Arg Leu Glu Glu Val
                 425                 430                 435

 Thr Leu Lys Asp Phe Lys Ala Ala Ile Asp Arg Glu Gly Asn His
                 440                 445                 450

 Arg Tyr His Phe Lys Ala Leu Asp Pro Glu Phe Gly Thr Val Lys
                 455                 460                 465

 Glu Glu Ile Phe His Asp Asp Asp Ala Ile Pro Gly Trp Glu Gly
                 470                 475                 480

 Lys Ile Val Ala Trp Val Glu Glu Asp His Gly Glu Asn
                 485                 490

<210> 2928
<211> 5938
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1687-1710
<223> Unknown base

<400> 2928
 cgacttatag aactggatga atctttcaaa agtgaacaca ctgtttttgt 50

 aacaccacct gagatccccc acctacccca tggtgaagaa ccccctttac 100

 agtacaggta ttcaagaggc agaatgtttg agattgaaag agagaagcaa 150

 tccatcatct gtgacgtagc tttctaagga ctgtggtatt ttcaaaaatc 200

 caaactttac agatccctaa tttttaggtg ctataatgga tttccagttc 250

 ttaggaacaa tttatttgaa agacctgaag gatttctaca agcaaagaag 300

 aacaaattgc cttcaaaatc aagtagtcct aatagccctt tgcccatgtt 350

 cagaagaaca aaacaggaaa ttaaatcagc ccataaaatt gcaaagaggt 400

 actcttccat ccctcagatg tggtctaggt gtctactgcg ccactgttat 450

 ggactgtggt ttatttgtct cccagcttat gtaaaagtct gtcattcaaa 500

 agtcagggct ctgaaaacag catatgatgt gcttaaaaaa aatgcagtca 550

 aagaagatgg atccacctga tgaggtatgc taccgcattc ttatgcaact 600

 ctgtggacaa tatgatcagc cagtgcttgc agttcgagtg ctttttgaaa 650

 tgcagaaagc tggtattgac cccaatgcca ttacttatgg ttattataat 700

 aaggctgttt tggaaagtac ctggccttca agaagtcgta gtggctattt 750

 tctttggaca aaagtaagaa atgtgtttta ggagtaacac agttcaaaag 800

 agctttaaag aagcatgcac acttatcaca aacaactctc tcaggtggcc 850

 agtctgatct tggatataat tcattatcta aagatgaagt tagaagaggg 900

 gatacatcta ctgaagacat tcaagaagaa aaagataaaa aagggagtga 950

 ttgtagttcc ttgtcagaga gtgagagtac aaaaggaagt gctgatgcct 1000

 tcctaagctc agttatcaaa attcttccag tatcgttcgc ctcactggta 1050

 caagtaacaa cagtgctggt aaaatatcag gagaaagcat ggaaagcaca 1100

 cctgagctgc tcttaatatc atctcttgaa gatacaaatg aaacacgaaa 1150

 cattcaaagt agatgcttca ggaaaagaca taaaagtgac aatgaaacta 1200

 atttgcagca gcaagtggtc tggggaaata gaaaccgtaa tcttagtgga 1250

 ggggtactga tgggatttat gctcaataga attaaccagg aagcaacccc 1300

 tggagatata gttgaaaaat tgggagctga tgcaaaaatt ctttcaaatg 1350

 ttatctcaaa aagcacgaga ccaaatactc ttgatattgg gaagccacct 1400

 ttaagatcaa aaagagacag tctagaaaag gaatctagtg atgatgatac 1450

 accttttgat ggttctaact atttggcaga taaagtggat tctcctgtta 1500

 tttttgactt agaagactta gacagtgaaa cagatgtatc aaaagcagga 1550

 tgtgttgcta cacaaaatcc caagaggatt caacgtatga acagcagctt 1600

 ttcagtaaaa ccttttgaaa aaactgatgt cgcaacagga tttgatcccc 1650

 tctctctttt ggttgctgag actgaacagc agcaaannnn nnnnnnnnnn 1700

 nnnnnnnnnn atgatagcaa aagcatttca acaccatctg ctaggcgtga 1750

 tttagctgaa gaaattgtga tgtatatgaa taacatgagc agtcctttga 1800

 caagtcgtac accaagcatt gatttacaac gggcatgtga tgataaatta 1850

 aataagaaaa gtccaccatt ggtcaaggca tgcagaagat ctagtctgcc 1900

 tcctaattct cctaagccag tgagacttac caaatctaaa agttacacaa 1950

 aaagtgagga gaaaccaagg gatagacttt ggtcttctcc agccttctca 2000

 cctacttgcc catttaggga agaatctcag gatacattaa cccactcatc 2050

 accttcattt aacttagata cactactagt acctaaacta gatgttctaa 2100

 gaaacagtat gttcactgct ggaaaaggag ttgcagagaa agcaagcaaa 2150

 tggtattcaa gattcaccat gtacaccaca tcatctaagg atcaaagttc 2200

 tgatcgtacc agtctttctt cagtgggagc ccaggattct gaatctacct 2250

 ctttaacaga tgaagatgtc tgccatgagt tggaaggacc tatctcctct 2300

 caagagacca gtgctacttc agggactaag agaattgatc tcagccgaat 2350

 aagcctggaa agttctgcat ccttggaagg atctctgtcg aagtttgcct 2400

 tacctgggaa atcagaagtg acatcttcct tcaacgcgag taatacaaat 2450

 atcttccaga actatgcaat ggaggttctc atctcaagtt gctctcggtg 2500

 tagaacttgt gattgtcttg tccatgatga ggaaatcatg gctggctgga 2550

 cagcagatga ttcaaatctc aatactacat gcccattctg tggcaatatc 2600

 ttcttaccct ttctgaatat agaaataaga gatttaagac gacctggaag 2650

 atactttcta aagtcaagcc catcaacaga aaatatgcac tttccatcct 2700

 ccatttcaag tcagacgagg cagtcttgca tttcaacatc agcctctggt 2750

 cttgacacat ctgctctctc tgttcaaggg aattttgatc taaatagcaa 2800

 atctaaactg caggaaaatt tttgcacccg aagtattcag atccctgcta 2850

 atagatcaaa aacagctatg tctaaatgtc caatatttcc aatggccagg 2900

 agtattagta cttctggccc cttggataag gaagatactg gaagacagaa 2950

 gctcatttct acaggcagcc tgccagctac tttacaagga gctacagatt 3000

 ctttaggttt agaatggcac cttccaagtc ccgatcctgt cactgttccg 3050

 tatcttagtc ctttagtggt atggaaagaa cttgaaagct tattggaaaa 3100

 tgaaggtgat catgcaataa cagtagcaga ctttgtggac catcatccaa 3150

 ttgttttttg gaacctggta tggtatttca gacgtcttga cttgcccagt 3200

 aacttacctg gattgattct ttcttctgag cactgtaaca agtattcaaa 3250

 gattccccgc cactgtatgt ctgaagatag caaatatgtt ttaatacaaa 3300

 tgttatggga caatatgaag ttacatcagg atccgggaca gcccttgtac 3350

 attctctgga atgcacacac ccaaaaatat ccaatggtcc atttattgca 3400

 aaaaagtgat aactcattta accaggaact gttgaaaagt atggtaaaaa 3450

 gcattaaaat gaatgatgtc tatggaccaa tgagtcagat tttagagaca 3500

 ctgaataagt gtccacattt taaaagacag aggagtttat acagagaaat 3550

 actatttctc tcacttgtgg cactgggaag agaaaacatt gatatagatg 3600

 cttttgataa agagtacaag atggcatacg atcgtctcac acctagtcaa 3650

 gtcaagagta cacacaactg tgatagacca ccaagtacag gggtgatgga 3700

 atgtcgaaaa acctttggag aaccttatct ttaagatgta tttgtatgtg 3750

 taaacattca atgtatattg tatagtcagt gtataaaata acacttttag 3800

 actctaaata ttttttcttc aatttttgaa aatacaattt gtaaatggtt 3850

 caaaagactc agacagctta tgtacagaat gtttgaagaa gagaatagtg 3900

 acaagtgggg agaaagccac tttgtttctc atttcttttt tcttcttctt 3950

 taactcccct gtaataggaa ataaagtatt tttgtgatga ggaaatccct 4000

 aaacaaaatt agttgccata aaatatgaca actgctttat ggtttctttt 4050

 ggaagagaca gattgaaaaa tcatgaatgg aatctaaaca gaaatgtcag 4100

 atgaacgtat ttcctgtttt catagactat tcaaatgttt tgaccatgaa 4150

 gttgtattat acatatttta aattgtttat agtaagttga tattttttta 4200

 atttttaaat ttaatatagc aaacttaaaa tgaatttaaa cttaagcaag 4250

 caagcgtgta ttttccttgt ctgctgctat ttgaagtaat tagtacagct 4300

 gcagatctct ctgtgtatat ctatctatat atatttttta ttacttggga 4350

 gaatgaattt taaaatgtca gtgctagtgt caagtgttgt cctaggattg 4400

 catgttagta cccctaagcc tgagtgtggg gagtgagtta tgcaagggta 4450

 gcgtgcactg cccagactga ctcatggagc cttgtgcaag gagagccaga 4500

 gaggttcact ataccatgac tccaaaattg tctctattgc taatagatac 4550

 gtatagtata cagggaaaac agcttataaa tccaaatatc aatttaaatt 4600

 ttaatattct acatgaaaac ttacattggg aaatatgcag acaagtgatt 4650

 atattccaaa ttttaccctt attttaatat ctaaaatatt gggtatgatg 4700

 caaattatac tatagaatat ttatctgaaa tatgacttac tggggtattc 4750

 tgttaatact atatataaat attcagaatt tttttcaaaa gtagaaaaat 4800

 tcccctctaa aagtacagcc agatagattt tcatccatat tgaggaactt 4850

 agctttttca acaagcttca gaatctgaag tctgtagaat ctaaaataca 4900

 gaaatatcca gaaatcagac aataaattga aagtttagac atcatgagta 4950

 ttaaatagct ttaaaaatat atttttagtc atattatttc taatgtaact 5000

 ttctttgggt aatttctggt aaggaaaaac atcttttggc tgctagaatt 5050

 agttatagat tttcaatatg tgtgtgtgtt tgcacacatt atcattagtg 5100

 aaggaattcc ctagccagct ttaaagaagg aaaaaatgga tagtcccaaa 5150

 ttaggtgtat aaagccagta gagtccacga cacttggact ggaggtatct 5200

 tggagtcctg agacttagaa tcagttcagc tgcagaaaac ccaccttttg 5250

 agttcacacc attagtgaat agcaccatgc tgaaacattt cacagcttcc 5300

 aactctggga aataatggag agagtttaaa aatgtaaaac ttcagttagt 5350

 ttggggctga acttgcttac ttgaaaaatc tggtgctagg cacatatatc 5400

 tgcctctcct ttgtaaatac cactccaata ttattcttta ctattcagat 5450

 ccaagcttca tgttctactt gttcttcatg ttctttaaat catttgaaag 5500

 ttgtcaactg agagaaacat ttcagagggg ggaggctttt ggcactggtg 5550

 ataaacatcc ctccaagaga accgtctggg gttctcttct atttgtggtt 5600

 ggtggttttt attcttttaa aaacagcttt cattgttgtt tactttttgt 5650

 gtaatacaaa caaaatgtag gaatcatagt ttattgattt caaatggctg 5700

 acaaagaatg agtaaaacca ttctttatgg ttttacgatt cagactcatt 5750

 tggaaaagcg aatgtaattt ttacctcctc tttccacccc aagttttgtt 5800

 tctgcttttg gagagggttg tatttcccct acttttaatc cctagggaat 5850

 attattgcac agatttagtc ttaaaaccta aaacacaaat acaaagtggt 5900

 aaacctgttc aaaagaaaat taaaatgtga atcattct 5938

<210> 2929
<211> 881
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 200-208
<223> unknown amino acid

<220>
<221> Unsure
<222> 1687-1710
<223> Unknown amino acid

<400> 2929
 Met Glu Ser Thr Pro Glu Leu Leu Leu Ile Ser Ser Leu Glu Asp
   1               5                  10                  15

 Thr Asn Glu Thr Arg Asn Ile Gln Ser Arg Cys Phe Arg Lys Arg
                  20                  25                  30

 His Lys Ser Asp Asn Glu Thr Asn Leu Gln Gln Gln Val Val Trp
                  35                  40                  45

 Gly Asn Arg Asn Arg Asn Leu Ser Gly Gly Val Leu Met Gly Phe
                  50                  55                  60

 Met Leu Asn Arg Ile Asn Gln Glu Ala Thr Pro Gly Asp Ile Val
                  65                  70                  75

 Glu Lys Leu Gly Ala Asp Ala Lys Ile Leu Ser Asn Val Ile Ser
                  80                  85                  90

 Lys Ser Thr Arg Pro Asn Thr Leu Asp Ile Gly Lys Pro Pro Leu
                  95                 100                 105

 Arg Ser Lys Arg Asp Ser Leu Glu Lys Glu Ser Ser Asp Asp Asp
                 110                 115                 120

 Thr Pro Phe Asp Gly Ser Asn Tyr Leu Ala Asp Lys Val Asp Ser
                 125                 130                 135

 Pro Val Ile Phe Asp Leu Glu Asp Leu Asp Ser Glu Thr Asp Val
                 140                 145                 150

 Ser Lys Ala Gly Cys Val Ala Thr Gln Asn Pro Lys Arg Ile Gln
                 155                 160                 165

 Arg Met Asn Ser Ser Phe Ser Val Lys Pro Phe Glu Lys Thr Asp
                 170                 175                 180

 Val Ala Thr Gly Phe Asp Pro Leu Ser Leu Leu Val Ala Glu Thr
                 185                 190                 195

 Glu Gln Gln Gln Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Asp Ser
                 200                 205                 210

 Lys Ser Ile Ser Thr Pro Ser Ala Arg Arg Asp Leu Ala Glu Glu
                 215                 220                 225

 Ile Val Met Tyr Met Asn Asn Met Ser Ser Pro Leu Thr Ser Arg
                 230                 235                 240

 Thr Pro Ser Ile Asp Leu Gln Arg Ala Cys Asp Asp Lys Leu Asn
                 245                 250                 255

 Lys Lys Ser Pro Pro Leu Val Lys Ala Cys Arg Arg Ser Ser Leu
                 260                 265                 270

 Pro Pro Asn Ser Pro Lys Pro Val Arg Leu Thr Lys Ser Lys Ser
                 275                 280                 285

 Tyr Thr Lys Ser Glu Glu Lys Pro Arg Asp Arg Leu Trp Ser Ser
                 290                 295                 300

 Pro Ala Phe Ser Pro Thr Cys Pro Phe Arg Glu Glu Ser Gln Asp
                 305                 310                 315

 Thr Leu Thr His Ser Ser Pro Ser Phe Asn Leu Asp Thr Leu Leu
                 320                 325                 330

 Val Pro Lys Leu Asp Val Leu Arg Asn Ser Met Phe Thr Ala Gly
                 335                 340                 345

 Lys Gly Val Ala Glu Lys Ala Ser Lys Trp Tyr Ser Arg Phe Thr
                 350                 355                 360

 Met Tyr Thr Thr Ser Ser Lys Asp Gln Ser Ser Asp Arg Thr Ser
                 365                 370                 375

 Leu Ser Ser Val Gly Ala Gln Asp Ser Glu Ser Thr Ser Leu Thr
                 380                 385                 390

 Asp Glu Asp Val Cys His Glu Leu Glu Gly Pro Ile Ser Ser Gln
                 395                 400                 405

 Glu Thr Ser Ala Thr Ser Gly Thr Lys Arg Ile Asp Leu Ser Arg
                 410                 415                 420

 Ile Ser Leu Glu Ser Ser Ala Ser Leu Glu Gly Ser Leu Ser Lys
                 425                 430                 435

 Phe Ala Leu Pro Gly Lys Ser Glu Val Thr Ser Ser Phe Asn Ala
                 440                 445                 450

 Ser Asn Thr Asn Ile Phe Gln Asn Tyr Ala Met Glu Val Leu Ile
                 455                 460                 465

 Ser Ser Cys Ser Arg Cys Arg Thr Cys Asp Cys Leu Val His Asp
                 470                 475                 480

 Glu Glu Ile Met Ala Gly Trp Thr Ala Asp Asp Ser Asn Leu Asn
                 485                 490                 495

 Thr Thr Cys Pro Phe Cys Gly Asn Ile Phe Leu Pro Phe Leu Asn
                 500                 505                 510

 Ile Glu Ile Arg Asp Leu Arg Arg Pro Gly Arg Tyr Phe Leu Lys
                 515                 520                 525

 Ser Ser Pro Ser Thr Glu Asn Met His Phe Pro Ser Ser Ile Ser
                 530                 535                 540

 Ser Gln Thr Arg Gln Ser Cys Ile Ser Thr Ser Ala Ser Gly Leu
                 545                 550                 555

 Asp Thr Ser Ala Leu Ser Val Gln Gly Asn Phe Asp Leu Asn Ser
                 560                 565                 570

 Lys Ser Lys Leu Gln Glu Asn Phe Cys Thr Arg Ser Ile Gln Ile
                 575                 580                 585

 Pro Ala Asn Arg Ser Lys Thr Ala Met Ser Lys Cys Pro Ile Phe
                 590                 595                 600

 Pro Met Ala Arg Ser Ile Ser Thr Ser Gly Pro Leu Asp Lys Glu
                 605                 610                 615

 Asp Thr Gly Arg Gln Lys Leu Ile Ser Thr Gly Ser Leu Pro Ala
                 620                 625                 630

 Thr Leu Gln Gly Ala Thr Asp Ser Leu Gly Leu Glu Trp His Leu
                 635                 640                 645

 Pro Ser Pro Asp Pro Val Thr Val Pro Tyr Leu Ser Pro Leu Val
                 650                 655                 660

 Val Trp Lys Glu Leu Glu Ser Leu Leu Glu Asn Glu Gly Asp His
                 665                 670                 675

 Ala Ile Thr Val Ala Asp Phe Val Asp His His Pro Ile Val Phe
                 680                 685                 690

 Trp Asn Leu Val Trp Tyr Phe Arg Arg Leu Asp Leu Pro Ser Asn
                 695                 700                 705

 Leu Pro Gly Leu Ile Leu Ser Ser Glu His Cys Asn Lys Tyr Ser
                 710                 715                 720

 Lys Ile Pro Arg His Cys Met Ser Glu Asp Ser Lys Tyr Val Leu
                 725                 730                 735

 Ile Gln Met Leu Trp Asp Asn Met Lys Leu His Gln Asp Pro Gly
                 740                 745                 750

 Gln Pro Leu Tyr Ile Leu Trp Asn Ala His Thr Gln Lys Tyr Pro
                 755                 760                 765

 Met Val His Leu Leu Gln Lys Ser Asp Asn Ser Phe Asn Gln Glu
                 770                 775                 780

 Leu Leu Lys Ser Met Val Lys Ser Ile Lys Met Asn Asp Val Tyr
                 785                 790                 795

 Gly Pro Met Ser Gln Ile Leu Glu Thr Leu Asn Lys Cys Pro His
                 800                 805                 810

 Phe Lys Arg Gln Arg Ser Leu Tyr Arg Glu Ile Leu Phe Leu Ser
                 815                 820                 825

 Leu Val Ala Leu Gly Arg Glu Asn Ile Asp Ile Asp Ala Phe Asp
                 830                 835                 840

 Lys Glu Tyr Lys Met Ala Tyr Asp Arg Leu Thr Pro Ser Gln Val
                 845                 850                 855

 Lys Ser Thr His Asn Cys Asp Arg Pro Pro Ser Thr Gly Val Met
                 860                 865                 870

 Glu Cys Arg Lys Thr Phe Gly Glu Pro Tyr Leu
                 875                 880

<210> 2930
<211> 3079
<212> DNA
<213> Homo sapien

<400> 2930
 tcttaaacaa ggagaagtgc cagaaagccc ggaagcaagg aaggaaagtg 50

 accaagcatg tggcaaaatg gatactgtgg atattgcaaa caactctact 100

 ttgggaaaac ccaagaggaa aagaagaaaa aagaaggggc atggctggag 150

 cagaacggga acgagaacgc agaaaaacaa ccaacaaaat gataacagca 200

 aagccgatgg ccagctggtc tcgagtgaaa agaaggcgaa catgaatctg 250

 aaagaccttt ccaagattag ggggagaaag agaggcaaac ctggaaccca 300

 ctttactcag agtgacagag ctccacagaa aagagtccga tcaagagctt 350

 caagaaagca caaagatgaa actgtggatt ttcaggctcc tttacttcca 400

 gtgacctgtg gtggggtgaa gggaatttta cataaggaga aattggaaca 450

 aggaaccttg gcaaagtgta tacagactga ggatggaaaa tggttcaccc 500

 ccatggaatt tgaaatcaaa ggaggctacg caagatcaaa gaactggagg 550

 ctgagtgtgc gctgtggcgg gtggccccta cgacggctga tggaggaagg 600

 atctctacct aatcctccaa gaatatatta caggaacaaa aagagaatac 650

 tgaagtctca aaacaatagc tcagttgacc cttgtatgag aaacttggat 700

 gagtgtgagg tgtgccggga cggaggggag ctgttctgtt gcgacacttg 750

 ttcaagagtc ttccatgagg actgccacat cccacctgtg gaaagtgaga 800

 agtaagtgac atgcaggcac ctctctttca tcctttaagg gaccttccac 850

 ctgccatgcg cactctccag cagaatgtct gcttgtgtct agatggggaa 900

 ggagcaggtt catcgggtac tgggacccag cagtgtgatc cagagagcag 950

 tgggagacgc tggcagcagg aggtaaatgc tctctgtgct ctcagggaca 1000

 cctcctctga tatgctgagg ccagtgttgg ggacctttgc ctacatactg 1050

 gtattgtcct ttccttgaag ttttgcagta gggtctcctg ccccaggggg 1100

 ttgaggaaaa aaaacaccag ttgtttatat tttgtgctta ttcatacaag 1150

 acaggaagca cggtcttagg cggatggagg cctgacgtcc ctggagttga 1200

 aagcccagtt tctgacacac aggcctggca ggcaggactc cttgtgctcc 1250

 cagcagctca gacagggaaa ggatagtccc cactcacggt gacaccacct 1300

 tcctgaggct tccctcctgc tgctaccact gatgcgaggg aaaggccagt 1350

 ggctggagac cccatgtgca gttcttggat actctgggag gtgttcccct 1400

 ccctcccatg actgagccca tcagccattc ctgaaggaag acagtggtag 1450

 ccacaggaac ggtggccatt tccaagctcc ctgccctctg ctcacccatg 1500

 tccaatctct caggaccccg tggaattgca tcttctgcag gatgaaggag 1550

 tctccgggaa gccaacagtg ttgtcaggaa tctgaggtcc tggagaggca 1600

 gatgtgtcct gaggaacagt tggtaaatca gatgcaaacc ccaagccttc 1650

 tcctttcccc tcacacgtga gaaccatgaa caagcgcaag ggcaggggaa 1700

 tgtactgaaa ggagcctgct ctaccgcgcc acacttcaat ggcactgata 1750

 gaacaccaca ccttgtttgc acaaaaaata actcagccat gacatgtctg 1800

 tttccaagag ccacacatgt tagagaaact tgaggaagaa gggtgtgagt 1850

 cgtgtgctgt gtctcatgca tgtgggctca ttctctccaa gctgcttttc 1900

 atttacggcc tctttctttt gcagaaatgt gagttcctcc tcttgaaagt 1950

 ctattgctgt tctgagagct ccttttttgc caagattcca tactattatt 2000

 atattagaga ggcgtgtcaa ggcctgaagg agcccatgtg gttggataaa 2050

 atcaagaaaa ggctgaatga gcacggttac ccccaagtgg aggggtttgt 2100

 acaagacatg cgcctcatct tccagaacca cagggcctct tacaagtata 2150

 aggattttgg ccaaatggga cttagactgg aggctgaatt tgagaaggat 2200

 ttcaaggaag tgtttgctat tcaggaaaca aatgggaaca gttgactggt 2250

 ttagtggatg ctgaaggcct tcaggaaata tgctactggt tgccactgac 2300

 ttcaaactga gagcacttgg gaaatagcac atgcagggag aggcttttct 2350

 ctgagcctcc ctcatccgcc caaaaacaaa tcctcaaaag aaatttgatc 2400

 atcatgaatc ccatccccaa gaatctcatc aaccagggaa gaggaactga 2450

 gatcacaggg aaggagattg gaggtgatac cagcacagac agactctcac 2500

 ctcttctcct gaggtctgct ccagacaaca tttattactc acaagacctt 2550

 tttcctccgt tttttttttg agatggagtc tcacacagtc acccgggatt 2600

 ggaatgcaat ggcgcgatct cagctcactg caacctctgc ctcccggatt 2650

 caagtgattc ccctgtctca gcctcccaag tagctgggat tacagtgcct 2700

 gccaccatgc ccagctaatt ttttgcattt ttagtagaga cggggtttca 2750

 ctatgttggc caggctggtc tcgaactcct gacctcatga gccgcccgcc 2800

 ttggcctccc aaagtgctgg gacgtgacag gagtgagcca ccacacctgg 2850

 ccactcgcaa gaccttttat ctgaaaacca gccaagcttt attcacgaca 2900

 cacttcttcc cttcactctc ccacttctgt ggtcaactcc ctgcagaact 2950

 cccaaactgc cgttcttttc gatagctcac gatggtgtat gagtgtcaat 3000

 catctgaccc ttcttggagt ctcatatttc gtggaactcc tgtgcaaaca 3050

 tatattatta aatttttttt cctcctgtc 3079

<210> 2931
<211> 245
<212> PRT
<213> Homo sapien

<400> 2931
 Met Asp Thr Val Asp Ile Ala Asn Asn Ser Thr Leu Gly Lys Pro
   1               5                  10                  15

 Lys Arg Lys Arg Arg Lys Lys Lys Gly His Gly Trp Ser Arg Thr
                  20                  25                  30

 Gly Thr Arg Thr Gln Lys Asn Asn Gln Gln Asn Asp Asn Ser Lys
                  35                  40                  45

 Ala Asp Gly Gln Leu Val Ser Ser Glu Lys Lys Ala Asn Met Asn
                  50                  55                  60

 Leu Lys Asp Leu Ser Lys Ile Arg Gly Arg Lys Arg Gly Lys Pro
                  65                  70                  75

 Gly Thr His Phe Thr Gln Ser Asp Arg Ala Pro Gln Lys Arg Val
                  80                  85                  90

 Arg Ser Arg Ala Ser Arg Lys His Lys Asp Glu Thr Val Asp Phe
                  95                 100                 105

 Gln Ala Pro Leu Leu Pro Val Thr Cys Gly Gly Val Lys Gly Ile
                 110                 115                 120

 Leu His Lys Glu Lys Leu Glu Gln Gly Thr Leu Ala Lys Cys Ile
                 125                 130                 135

 Gln Thr Glu Asp Gly Lys Trp Phe Thr Pro Met Glu Phe Glu Ile
                 140                 145                 150

 Lys Gly Gly Tyr Ala Arg Ser Lys Asn Trp Arg Leu Ser Val Arg
                 155                 160                 165

 Cys Gly Gly Trp Pro Leu Arg Arg Leu Met Glu Glu Gly Ser Leu
                 170                 175                 180

 Pro Asn Pro Pro Arg Ile Tyr Tyr Arg Asn Lys Lys Arg Ile Leu
                 185                 190                 195

 Lys Ser Gln Asn Asn Ser Ser Val Asp Pro Cys Met Arg Asn Leu
                 200                 205                 210

 Asp Glu Cys Glu Val Cys Arg Asp Gly Gly Glu Leu Phe Cys Cys
                 215                 220                 225

 Asp Thr Cys Ser Arg Val Phe His Glu Asp Cys His Ile Pro Pro
                 230                 235                 240

 Val Glu Ser Glu Lys
                 245

<210> 2932
<211> 3717
<212> DNA
<213> Homo sapien

<400> 2932
 catgcatata aacttatttg taatacaatg aaaagaagac aagatgtttc 50

 tccaaataga gattttctaa cacatttcta caatataatg cattgtggat 100

 tacttcatat tgaccaggat attgtcaata caatcatcaa acactgctca 150

 cctcaatttt tttcacttgg tttgcctggt gccacaatgc ttattatgga 200

 ttttattgta gcagctggta gagtggcttc ttcagctttt ctcaatgcac 250

 caagagtaga agcacaagtt cttctgggat ctttggtttg ctttcccaac 300

 ttatattgtg aactgccttc tcttcatccc aacattcctg atgttgctgt 350

 gtctcagttt acagatgtta aggaacttat aatcaaaact gtattaagct 400

 cggcaagaga tgagccctct ggtcctgcac gatgtgtagc actttgtagt 450

 ttaggtattt ggatttgtga agaactagtc catgagtctc atcatcctca 500

 aattaaggaa gctctgaatg tgatttgtgt ttccttaaag tttactaata 550

 aaacagtagc ccacgtagct tgtaacatgc ttcacatgct ggttcattat 600

 gtacctagac ttcagattta ccagcctgat tctcccttga aaattattca 650

 aatcctaata gctaccatca cccatctttt accaagtaca gaggcttcat 700

 cttatgaaat ggacaagagg ttggtagtat ctttacttct ctgccttctg 750

 gactggatca tggccttacc tctaaagaca ctgctccaac catttcatgc 800

 tacgggagca gaaagcgata aaacagaaaa atctgttctc aattgcattt 850

 ataaggtttt acatgggtgt gtttatggag ctcagtgttt tagcaatcca 900

 aggtattttc ccatgagcct ctctgatttg gcatctgtag attatgatcc 950

 ttttatgcat ttggaaagtc tgaaagagcc tgagcctctg cactctcctg 1000

 actcagaacg atcttctaaa ctccagccag taacagaagt gaaaactcaa 1050

 atgcagcatg gattaatctc tatagcagcc cgcactgtta ttacacatct 1100

 ggtaaatcac ctgggccatt atccaatgag cggtggtcct gctatgctaa 1150

 caagtcaggt gtgtgaaaat cacgacaatc attacagtga aagtactgaa 1200

 ctttctcctg aactctttga gagtccaaat atccagttct ttgtgttaaa 1250

 taatacaacc ttagtgtcct gtatccagat cagatcagaa gagaatatgc 1300

 ctggaggagg tttatctgct ggccttgcat cagccaattc aaatgtcaga 1350

 atcatagtac gtgatctctc tggaaaatat tcatgggatt ctgctatact 1400

 gtatggccca cctcctgtaa gtggcttgtc agaacctaca tctttcatgc 1450

 tttcattgtc tcaccaagag aagccagaag agcctccgac atctaatgaa 1500

 tgcttagaag atataaccgt aaaagatgga ctttctctcc agtttaaaag 1550

 atttagagaa actgtaccaa cttgggatac aataagagat gaagaagatg 1600

 ttcttgatga gctcttgcag tatttgggtg ttactagtcc tgaatgctta 1650

 cagagaactg gaatctcact taatattcct gctccacaac ctgtgtgcat 1700

 ttctgaaaaa caagaaaatg atgttattaa tgctatcctt aagcaacata 1750

 cagaagaaaa agaatttgtt gagaagcact ttaatgactt aaacatgaaa 1800

 gctgtggaac aagatgaacc aatacctcaa aaacctcagt cagcatttta 1850

 ttattgcaga ttgcttctta gtatattggg aatgaattcc tgggacaaac 1900

 ggaggagctt tcatctcctg aagaaaaatg aaaagctact tagagaactt 1950

 aggaacttgg attcaaggca gtgccgagag acacacaaga ttgcagtatt 2000

 ttatgttgct gaaggacaag aagacaaaca ctccattctc accaatacag 2050

 gaggaagtca agcatatgaa gattttgtag ctggtcttgg ttgggaggta 2100

 aatcttacaa accattgtgg ttttatggga ggactacaaa aaaacaaaag 2150

 cactggattg accactccat attttgctac ctctacagta gaggtaatat 2200

 ttcacgtgtc aacaagaatg ccttctgatt ctgatgattc tttgaccaaa 2250

 aaattgagac atttgggaaa tgatgaagtg cacattgttt ggtcagagca 2300

 tactagagac tacaggagag gaattattcc cacagaattt ggtgatgtcc 2350

 ttattgtaat atatccaatg aaaaatcaca tgttcagtat tcagataatg 2400

 aaaaaaccag aggttccctt ctttggtccc ctttttgatg gtgctattgt 2450

 gaatggaaag gttctaccca ttatggttag agcaacagct ataaatgcaa 2500

 gccgtgctct gaaatctctg attccattgt atcaaaactt ctatgaggag 2550

 agagcacgat acctgcaaac aattgtccag caccacttag aaccaacaac 2600

 atttgaagat tttgcagcac aggttttttc tccagctccc taccaccatt 2650

 taccatctga tgccgatcat taaatatcag ttctgtttat ctgaaggctc 2700

 ctacccagag attctaccca gtgaaactcc cacagcaacg caggtagatg 2750

 gggctgacct ggcctctcca atgtctcctc gaactagcaa aagccgcatg 2800

 tccatgaagc tgcgtcgttc ctctggctca gccaataaat cctaaggaga 2850

 caagcagccc agcagtgatc agcagtagcc accttagcac gaacataggg 2900

 ttaacccttt caggccttca tgtctgccat aacatgcatg tttcttcctg 2950

 tacatttatt tgagaaaaca ctggatttaa ataattttaa ataatttgta 3000

 gcttaatatt aaagatttaa gttatttatt gtttcatttt ttttcccaca 3050

 atccaagctg ccatattttg agggcagggg gagttttatt ctacaccctt 3100

 taccttccta gataattatg tctaagtagt tttatcttta atttcatggt 3150

 taactgtgag ccaaaataca attggacaat tagtctcatt atttattgtg 3200

 ccccattgca actttatggt tcaataaata tataattttt tacaaatgta 3250

 aaattttaca tttaagcatt tgtaaagtta cagcaaaaga tgtacctgtt 3300

 aatacacaga atgtgtacag attatttgtt atgacaataa aacactcaaa 3350

 ataaatggtc tttagcatct caaattccaa ctgaaatcat tttagtatta 3400

 actcttcttc ccaaagcaat gtctcatttc ttggctgtgc aggtgatgcc 3450

 atgttatatc caataactag aaaaatcact gtgctgaact tttatgttta 3500

 gcttccaagt atttttctaa tgttttgcat ttcaagtggt atcactgtta 3550

 aatgccattt gttttcagat tgtggccttt tattattggc tgctagatcc 3600

 tggtgtttct atgttctttt ttaagcacca aaaagaagat ggggaagaaa 3650

 agaaggaaaa ttttctgata taaatatgtt gttcaaatta tgagtattat 3700

 ttaaaaaaaa aaaaaaa 3717

<210> 2933
<211> 890
<212> PRT
<213> Homo sapien

<400> 2933
 His Ala Tyr Lys Leu Ile Cys Asn Thr Met Lys Arg Arg Gln Asp
   1               5                  10                  15

 Val Ser Pro Asn Arg Asp Phe Leu Thr His Phe Tyr Asn Ile Met
                  20                  25                  30

 His Cys Gly Leu Leu His Ile Asp Gln Asp Ile Val Asn Thr Ile
                  35                  40                  45

 Ile Lys His Cys Ser Pro Gln Phe Phe Ser Leu Gly Leu Pro Gly
                  50                  55                  60

 Ala Thr Met Leu Ile Met Asp Phe Ile Val Ala Ala Gly Arg Val
                  65                  70                  75

 Ala Ser Ser Ala Phe Leu Asn Ala Pro Arg Val Glu Ala Gln Val
                  80                  85                  90

 Leu Leu Gly Ser Leu Val Cys Phe Pro Asn Leu Tyr Cys Glu Leu
                  95                 100                 105

 Pro Ser Leu His Pro Asn Ile Pro Asp Val Ala Val Ser Gln Phe
                 110                 115                 120

 Thr Asp Val Lys Glu Leu Ile Ile Lys Thr Val Leu Ser Ser Ala
                 125                 130                 135

 Arg Asp Glu Pro Ser Gly Pro Ala Arg Cys Val Ala Leu Cys Ser
                 140                 145                 150

 Leu Gly Ile Trp Ile Cys Glu Glu Leu Val His Glu Ser His His
                 155                 160                 165

 Pro Gln Ile Lys Glu Ala Leu Asn Val Ile Cys Val Ser Leu Lys
                 170                 175                 180

 Phe Thr Asn Lys Thr Val Ala His Val Ala Cys Asn Met Leu His
                 185                 190                 195

 Met Leu Val His Tyr Val Pro Arg Leu Gln Ile Tyr Gln Pro Asp
                 200                 205                 210

 Ser Pro Leu Lys Ile Ile Gln Ile Leu Ile Ala Thr Ile Thr His
                 215                 220                 225

 Leu Leu Pro Ser Thr Glu Ala Ser Ser Tyr Glu Met Asp Lys Arg
                 230                 235                 240

 Leu Val Val Ser Leu Leu Leu Cys Leu Leu Asp Trp Ile Met Ala
                 245                 250                 255

 Leu Pro Leu Lys Thr Leu Leu Gln Pro Phe His Ala Thr Gly Ala
                 260                 265                 270

 Glu Ser Asp Lys Thr Glu Lys Ser Val Leu Asn Cys Ile Tyr Lys
                 275                 280                 285

 Val Leu His Gly Cys Val Tyr Gly Ala Gln Cys Phe Ser Asn Pro
                 290                 295                 300

 Arg Tyr Phe Pro Met Ser Leu Ser Asp Leu Ala Ser Val Asp Tyr
                 305                 310                 315

 Asp Pro Phe Met His Leu Glu Ser Leu Lys Glu Pro Glu Pro Leu
                 320                 325                 330

 His Ser Pro Asp Ser Glu Arg Ser Ser Lys Leu Gln Pro Val Thr
                 335                 340                 345

 Glu Val Lys Thr Gln Met Gln His Gly Leu Ile Ser Ile Ala Ala
                 350                 355                 360

 Arg Thr Val Ile Thr His Leu Val Asn His Leu Gly His Tyr Pro
                 365                 370                 375

 Met Ser Gly Gly Pro Ala Met Leu Thr Ser Gln Val Cys Glu Asn
                 380                 385                 390

 His Asp Asn His Tyr Ser Glu Ser Thr Glu Leu Ser Pro Glu Leu
                 395                 400                 405

 Phe Glu Ser Pro Asn Ile Gln Phe Phe Val Leu Asn Asn Thr Thr
                 410                 415                 420

 Leu Val Ser Cys Ile Gln Ile Arg Ser Glu Glu Asn Met Pro Gly
                 425                 430                 435

 Gly Gly Leu Ser Ala Gly Leu Ala Ser Ala Asn Ser Asn Val Arg
                 440                 445                 450

 Ile Ile Val Arg Asp Leu Ser Gly Lys Tyr Ser Trp Asp Ser Ala
                 455                 460                 465

 Ile Leu Tyr Gly Pro Pro Pro Val Ser Gly Leu Ser Glu Pro Thr
                 470                 475                 480

 Ser Phe Met Leu Ser Leu Ser His Gln Glu Lys Pro Glu Glu Pro
                 485                 490                 495

 Pro Thr Ser Asn Glu Cys Leu Glu Asp Ile Thr Val Lys Asp Gly
                 500                 505                 510

 Leu Ser Leu Gln Phe Lys Arg Phe Arg Glu Thr Val Pro Thr Trp
                 515                 520                 525

 Asp Thr Ile Arg Asp Glu Glu Asp Val Leu Asp Glu Leu Leu Gln
                 530                 535                 540

 Tyr Leu Gly Val Thr Ser Pro Glu Cys Leu Gln Arg Thr Gly Ile
                 545                 550                 555

 Ser Leu Asn Ile Pro Ala Pro Gln Pro Val Cys Ile Ser Glu Lys
                 560                 565                 570

 Gln Glu Asn Asp Val Ile Asn Ala Ile Leu Lys Gln His Thr Glu
                 575                 580                 585

 Glu Lys Glu Phe Val Glu Lys His Phe Asn Asp Leu Asn Met Lys
                 590                 595                 600

 Ala Val Glu Gln Asp Glu Pro Ile Pro Gln Lys Pro Gln Ser Ala
                 605                 610                 615

 Phe Tyr Tyr Cys Arg Leu Leu Leu Ser Ile Leu Gly Met Asn Ser
                 620                 625                 630

 Trp Asp Lys Arg Arg Ser Phe His Leu Leu Lys Lys Asn Glu Lys
                 635                 640                 645

 Leu Leu Arg Glu Leu Arg Asn Leu Asp Ser Arg Gln Cys Arg Glu
                 650                 655                 660

 Thr His Lys Ile Ala Val Phe Tyr Val Ala Glu Gly Gln Glu Asp
                 665                 670                 675

 Lys His Ser Ile Leu Thr Asn Thr Gly Gly Ser Gln Ala Tyr Glu
                 680                 685                 690

 Asp Phe Val Ala Gly Leu Gly Trp Glu Val Asn Leu Thr Asn His
                 695                 700                 705

 Cys Gly Phe Met Gly Gly Leu Gln Lys Asn Lys Ser Thr Gly Leu
                 710                 715                 720

 Thr Thr Pro Tyr Phe Ala Thr Ser Thr Val Glu Val Ile Phe His
                 725                 730                 735

 Val Ser Thr Arg Met Pro Ser Asp Ser Asp Asp Ser Leu Thr Lys
                 740                 745                 750

 Lys Leu Arg His Leu Gly Asn Asp Glu Val His Ile Val Trp Ser
                 755                 760                 765

 Glu His Thr Arg Asp Tyr Arg Arg Gly Ile Ile Pro Thr Glu Phe
                 770                 775                 780

 Gly Asp Val Leu Ile Val Ile Tyr Pro Met Lys Asn His Met Phe
                 785                 790                 795

 Ser Ile Gln Ile Met Lys Lys Pro Glu Val Pro Phe Phe Gly Pro
                 800                 805                 810

 Leu Phe Asp Gly Ala Ile Val Asn Gly Lys Val Leu Pro Ile Met
                 815                 820                 825

 Val Arg Ala Thr Ala Ile Asn Ala Ser Arg Ala Leu Lys Ser Leu
                 830                 835                 840

 Ile Pro Leu Tyr Gln Asn Phe Tyr Glu Glu Arg Ala Arg Tyr Leu
                 845                 850                 855

 Gln Thr Ile Val Gln His His Leu Glu Pro Thr Thr Phe Glu Asp
                 860                 865                 870

 Phe Ala Ala Gln Val Phe Ser Pro Ala Pro Tyr His His Leu Pro
                 875                 880                 885

 Ser Asp Ala Asp His
                 890

<210> 2934
<211> 17073
<212> DNA
<213> Homo sapien

<400> 2934
 ggatccatgc ccagaattat tcacgaaatt cacttaaaat agcatatatg 50

 cttgaaccca ggagtctgag gctgcagcga gctatgatca tgtcactgca 100

 ctccagccca gcctgggcga cagagcaaga ctctgtgtct aaagaaatga 150

 aaataaaaat aaataaaata gcatatacag gcaacaatcc aaatgttcat 200

 tgcagaaatt atgattatta ttgtttttct tttagaggca gggtgtcact 250

 ctgttgccca gactaatctt gacctcctgt gatcctcaag agatcctccg 300

 gtctctgctt cccaaagttc ttggattaca ggtgtgaggc actgggccta 350

 gacattgcag ggattattaa accatggtgc atactaccat taaaggtatg 400

 aggtaggttt tatatgctga cctagaaaga tggtgcaaca ccatagggga 450

 acaagaaggc tgcaaagtgg cagcacagca ggagtcttta agaaataggt 500

 atttgtttca gcttaagaag tgtctggctg ggcgtggtgg ctcacacctg 550

 taatcccagc acttagggag gcttaggtgg gcggatcact tgaggttagg 600

 agttcaagac cagcccagtc aacaccggtg aaaccccatc tctactaaaa 650

 atacaaagaa attagctggg cttggtggca ggtggctgta atcccagcta 700

 ctcaggagct gaggcaggag aatcatctga acccgggagg ccgaggttgc 750

 agtgagccta gatcgcacca ctgcactcca gcctgggtga cagagtaaga 800

 ctcggtcaaa aaaaaaaaaa aaaaagaccg ggtgcgaggt ctctcgcctg 850

 taatcccagc actttgggag gcctaggcag gaggatcaca aggtcaggag 900

 atcgagacca tcctggccaa catggtgaaa ccccatctct actaaaatac 950

 aaaaattagc cgggtgtgat ggcacacgcc tgtagtccca gctactcagg 1000

 aggctgaggc aggggaatcg cttgaaacca ggaggtggag gctgcagtga 1050

 gccgagatca cgccactgca ctccagcctg gcgacagagc aagactccat 1100

 ctcaaaaaag aaaagaaaac aaacaaacaa acaaaatccc caaaaagcaa 1150

 aagtgtctgc atggacttgt gcctaactac tcacagtggc tacttcttgg 1200

 gggaggtgaa aggggaccct gttaaagaat ttttcttctg tattgttttt 1250

 cttcaactga gtctgcatta attttatatt taatactctc cccacccctg 1300

 atgctcacag gttgctttag ctggtggaag gagaacctgc acctctggtt 1350

 ttggcaaagt gtagaagggg acaagggcac tgctctgcac ctgcacaggt 1400

 tcttgcctcc tggggtcagt ttaatgaatc tcagtggtgt ttcttgggaa 1450

 gaacacagtg gacactcact tgccagtcag tagacaaatc actgaagtcc 1500

 atgtctggca gttctcaatg tcatggggac tgtaaggttg tcatgtctca 1550

 cagttccctg acttagaaga ttagtggtga cagacacttc tcagctctgc 1600

 tcgggagagc agctctgtaa tgcgcttgtg gtttcagatg tgggcggcct 1650

 gtgtgaacct gtcgtgcaaa gctcacgtca ccaactgctg cagttatctc 1700

 ctgaatcagg ctgagggtct ttgctgtgca cccagagata gttgggtgac 1750

 aaatcacctc caggttgggg atgcctcaga cttgtgatgg gactgggcag 1800

 atgcatctgg gaaggtgagt ctgtgctttg ggcttcccaa cctctcaagt 1850

 cagcatgaaa ttcagaaggc agagagggac atgtggccct ccaactcggg 1900

 gcccagggag ccactgtggc atttgagagc gccaccctag ctttacctcc 1950

 tctggtgtcc tggccttgtg tatctcttag agatggcaaa atttgcagcc 2000

 ctgacctcaa ggattacaaa ctaatttcca gtcctgtagg ggtcatgggt 2050

 tctgctgtgg ccagtgtggc actgagtttg tcaggcagaa tttctaatta 2100

 tggaaggaac tctgcttcct cagtgattga actgaccttt gtgggggtgc 2150

 ctttgtgggg tgagaatggg catacttggg cctcagttgt gatggccatg 2200

 gggtggagct gaggtctagg cccagggctg ggaaagcttc taccaacccc 2250

 gaggcatttg ggtgttttag ggcagaagag gagccaggag gatgggtatg 2300

 ccccactgga gctgtgtgtg gggcagcagg tgagggtggg attccagagg 2350

 gagggtcaac ccagccaagc agaggaaggg gaggagaggg tttgttttgg 2400

 aaagaacatc accctctcag tttcctgggg tctggatagc ctgttcttgt 2450

 gatgagctgg aggatgtggg ccctgcttgg atcctcctct cccctccctg 2500

 cccccatttt ctcttcctgt gatttatgct gttctgggct caccctcttc 2550

 ccagagctct cacgctacag ctgacaggca gggcaggcgt tttaattatt 2600

 attaattttt ttttgagaca gagtttgaga cagtatcaag agtgggtatc 2650

 ctctcagcgt gtcttcaagt agcatcccag agccccgctc ctgggtaccc 2700

 acaacatgaa caccgtccag aagcaagggc agcctctgca ggtggggcgg 2750

 gggttggaaa acatttatca aacggttgag ttgggtgcag gggatgcaac 2800

 atgatcaaac agggtcttgc ctccaggagc ctcatgtagg gacaacgcac 2850

 agtgatgacc ttcaactgca gtggggcagc aaggctgtgg gaggggtgtt 2900

 ttgggcagag caggcgacgt gggtacctct tcaccaagac agcaggaaga 2950

 gcacggacat cattttcccg tctcacctcc agactcccag gggactgtgc 3000

 caatatcctc actggagccc tgcccatggc cactgctcaa cccttgggcc 3050

 ctgtcagttc agggctgtgc agaaggagag ttgcctgtgc tcaggctcag 3100

 gggttccgtc cagctaagga ggcctactag gggactgggg aaaggcctca 3150

 tgaaggacca ggcctgtgat ggggagggaa gatggcagag gggacagtgg 3200

 gaagcagagc agcaggggtc tcctccacgc ctctctgtac ttctcccacc 3250

 cacccttgcc tgctcccctc tgccctgggt atgtgccctt gtccacccaa 3300

 cacctctgca gtgccaagtc cagccctgac ttcttcctga gctgtggccc 3350

 agcgttccca caggcattta cctcacggat gcagcactgc ccctcatcct 3400

 cttctctgaa agtgtgtggg aaatgcttct tggtgccatc tctctcccac 3450

 cctgccttcc ctgcaccttc tctatgaggt gtctgttgtc tctgtacttg 3500

 cctccagctg gcctttcaga ccccatccct ccctgcctcc tgcccatccc 3550

 tacccctgtc agcaccttac atactctgtg cccaacagca ttggggattc 3600

 ccactgtgct gaaggaagtc ctcatgtggt ccagagaggg agctggcccc 3650

 tgctcccatt tccagcacca ttttctggca caggctccat gtccccaggc 3700

 tccagctgct tctggggtac caaggtctgc atttcttcct cttcccccag 3750

 cagacagaag accttgctgg acaggtgtcc acttcaatag taacttctga 3800

 ggctgccagc ctcctgaatg gtccagaaga accagaccct tccccgcccc 3850

 cattaaaaaa gacaaaatat ggccaggcat gttggctcat gcctgacatc 3900

 ccagcacttt gggaggccaa agcaggtgaa tcacttgagg ccaggagtac 3950

 gagaccagcc tgacaaacat ggtgaaaccc tgtgtctact aaaaatacaa 4000

 aaattagcca ggcgtggtga ctcatgcttg taaatgcttg taatcccagc 4050

 tacttgggag gctgaagcag gaggatcact tgaactcggg aggcagaggt 4100

 tgcagtgagc cgagatcacg ccactgtgtt ccagcctgag cgacagagcg 4150

 acactccgtc taaaaaaaaa aaatatatat atatatacac acatatatat 4200

 atgcataata gtctctgtgt aacagtaagt ggatgcagta actggtgtga 4250

 gggcaacttg gagagtgtgc ttggaggcac agagatgctc agggctgcct 4300

 ggactgcctc catgatggtg gcctgctctg tattaggtga gtgttcagga 4350

 aaggtgaggg cagggcagcc cacagcttca cagtggccca gggaagcagg 4400

 gcaggcaggc tatgaggcct agtaggcatc tgggccagac tttgacactg 4450

 aggccatgga atgggtgggg ctctgagaac agaccaaagt gatcatgggc 4500

 tgaaggctat gtccacagat ccaaggcggg ataggctgtg ctgggcagtg 4550

 atgtcagcca ggctccccag cgggactggg ggtgtcaggg gcagctctgt 4600

 cccaggtggc agacactggt ttcccctcct gctctcacaa ccggcctgtt 4650

 accaggtgtt gtctgagctg tggtgaggct tccctggtga cattcaggag 4700

 cagggagcct gtgagtaagg gtgtatgcat ctgccctgac tgcctggccc 4750

 tgtggtcaag gatgggggaa ggcagctctg cctgcagctc caccccattt 4800

 ataaagcact gtggtgcctt ctgctggggc atgtgctgag tggtgcctcg 4850

 caggcactgc cctcgggaag ttcacaggct tatgtggaag ctggtgggaa 4900

 tgggccaaga agagaggtgt caggagccag gtattgggca ggtcccaggt 4950

 ctctgagcct cagtttcttc atctgtagga gggtggtgac cctgccctgc 5000

 tcagcttacc aggtacagat gtaagttttc agtgcagagg aaaagcagag 5050

 aagttcccct cagatggcca tacccccttg tcgctgtacc caactctccg 5100

 gtcctacttt gtagctctca ggtgtcacat gtggatcctg ccctaccatc 5150

 ccccttccct gtctagaaac gaggcctgct gagcttggag ccatcccact 5200

 ccctgctctc aagccgtctg ctcctgggtt agcctgtggc tggcctggcc 5250

 tgattctaca tagatgtggg tgtttctcca ctgctggggc agcagttgtc 5300

 cattctgggg cctgggtcag ctctcagctg tggccgttgt gcctgtgctt 5350

 ccccaggtcc tggtggtgac tccaaccctg ccctcacata tcccaagagc 5400

 aggctgactg ccttccccat tcccaccttt ccagtaactg ctgcaagaac 5450

 ggacagacac tgctgcagag aacttgccac ggtgtttcat gctgtggctg 5500

 gtggttccag gctgcacgct ccattctagg aaagggtgag gcttcctgat 5550

 catcagtctt aacaggggac tgtcctatgg gtacctgtat acgctgccgg 5600

 gagtggggca gagtggggtt agagtagtgc ctgctgccca ttggggttgt 5650

 gcgggttcct taagggctgt agtctgtgtg cgtgtctggt tttttcctcc 5700

 tccttatcag taatcagtct tgtataacca ggctggccct gcttcctgcc 5750

 taggggctat cggtgtacca tctggagttg caaatggggt gatagggcgt 5800

 cagcggcctt cccacaccca agcacttcct gacacccagc ccctcatctc 5850

 tagccaacct ctggctcccc tagggatcct ggggctcagg cctcacgctc 5900

 cagcatccgg gggctttgcc ttctggtgtt gctcttcttt gcaggtgcct 5950

 tggaacaggg gtgcaacaga gttcagaaag tgccatctgt tgcatggata 6000

 ccctgctgcc accctcgtcc acctttctgg ggcagaacag ttggatgggt 6050

 ctttatttaa gaggacaaaa gggagagaga atgcatagag gctgggtctg 6100

 gtgtcacgcc tgtaatccca acactttggg aggccaaggc aggtggatcc 6150

 cttgaggtca ggaggtcaag actagcctgg ccaacatggt gaaaccccgt 6200

 ctctactaaa aatacaaaaa aaaaaaaatt agctgggcat ggcgggagat 6250

 gcctgtaatc ccagctactc gggaggctga ggcaggataa tcacttgaac 6300

 ccaggaggcg gaggttgcag tgagccaaga tcacaccact gcactctagc 6350

 ctgggtgaca gagggagact gtctcaaaaa aaaaaatttg cttagaattt 6400

 gtctgtgtga ccctgggcaa gtcatttccc ctccttggga ctcagttcct 6450

 tgcctgtgaa cggggacagt gcttctccct tacagagctg ttgtgagaat 6500

 taaagtagaa aatgtaccta tggtggttgt tggtagtgac cagttccccc 6550

 aaccctgact cccctgcagg atggggcctg ggcccgggaa tgggggatgg 6600

 gctggcagag gatgactgtc ccagagagga gtcttctcgg cagatgtgga 6650

 gacctagctg agtcagaggc caggatctaa gtttgagggt gttccttaca 6700

 ccctgcagcc atgagtcttt ggctgagtca aatggccttt ctgagctcag 6750

 ttccttatca gtaaagcctg gacagtggtc caggacgctg gacactgtgt 6800

 gagtgttagg acacaggaca ctgtgtgagt gcaggtgggg acccatggag 6850

 cactctgctg gggagcaatt catggggagc acccctccag agagggatga 6900

 tttgcacagg gccctcagcc cagtcccttg caggctggac cttggagagt 6950

 gaggccctga ggcgagacat gggcacctgg ctcctggcct gcatctgcat 7000

 ctgcacctgt gtctgcttgg gagtctctgt cacaggggaa ggacaaggtg 7050

 agggctgggc actaatgtct gtatgaggtg ggtggagaac tagggcatgt 7100

 ttgggggact gggttgtccg atgtcaagcc tctagggaaa ggtttggccc 7150

 aaactgtgct ggggcatgtc ctctaggggt cagcctggac ctcagtctct 7200

 agtctcccta cttttacctc cctaccttca ttccctggac cgactgtagt 7250

 ctcccttcct tcactctctt gacgcctctc cagatctgac ttgcccgtgt 7300

 accacaggtc agagcccatc acttcccagg cctcccagtg cttccctgga 7350

 cagattctgg gatcatttac tggtgactgc cctgctaggg tgtcagctgt 7400

 cagatcctcc ccaacccccg agctcagctc tggcctgaag tacttaccgt 7450

 gggctcctga tggtcactgt ctccagggcc aaggtctaga accttcacct 7500

 gcctcaccaa caacattctc aggatcgatt gccactggtc tgccccagag 7550

 ctgggacagg gctccagccc ctggctcctc ttcaccaggt gagcatggag 7600

 ggccatgccc acctggacag ggatgagggt gagttcccca ggattgaagc 7650

 agctatgcca ggacagtgta gcagccccgt ggtgctgaca aatgcccttt 7700

 ccagcaacca ggctcctggc ggcacacata agtgcatctt gcggggcagt 7750

 gagtgcaccg tcgtgctgcc acctgaggca gtgctcgtgc catctgacaa 7800

 tttcaccatc actttccacc actgcatgtc tgggagggag caggtcagcc 7850

 tggtggaccc ggagtacctg ccccggagac acggtgagca gcagctatag 7900

 gtctggggcg gggccgcttg gcaagaacat cctggctgct tgggggtttg 7950

 gagcagggcc ttgcagcctg tgagtggccc agtgagtgtt ctcagtccca 8000

 gccgagtgag atccagggct gggggcaggc ttggcccttg ggaggggagg 8050

 gcccatatgg ttactgcagg ggcagggttt tggcaggaaa taaacatgca 8100

 cggctgctag ttggggcagg ggctggcact tgagtcatgt gaaatgcact 8150

 tcagtcatac caggaaggac tccaataaga tgctgggaaa agcttccagc 8200

 agcagactgt gaaggaaagg gaaagcaaga tttagaaacc acctagtcta 8250

 ggtgcagagg ccagaggaag tcattgctgt cctgtcccgc ctggggcttt 8300

 tgtggaccag tctcccagtg aggtgcctgg tctgagaggg ccttgaccat 8350

 tccccttggg agtctttcag accccagtct tgtgtgttct gactgacaca 8400

 cccagaccca tggggcttca gcctcacatg gattcactct gttccagtta 8450

 agctggaccc gccctctgac ttgcagagca acatcagttc tggccactgc 8500

 atcctgacct ggagcatcag tcctgccttg gagccaatga ccacacttct 8550

 cagctatgag ctggccttca agaagcagga agaggcctgg gaggtaacac 8600

 tttggctggc tttccctggg ggcctctctc ctgggaacag cagtccaggg 8650

 tagactcccc actctacata gggagatgtc aacttgtagt gatgagaagg 8700

 gaggaactag agcggggtgt gtgtgcacac acacatgctg gcatgcagat 8750

 gtgtatgctt tatgtgtgtg tatgggagta gggtgagtgc gcctgtgtct 8800

 ctgtgtgtgc acataagtgt ggtgagtgtg catgtatgtg tttatgtgta 8850

 cacatatgta actgtgcaca ctcatgtttg tgtgcccatg tttgtgtgtt 8900

 tatatgtaag tgtacatatg tgtgtgcctg tgccttgcat ttgtgtgagt 8950

 gtgcacatgg gcatgcctat gtgtatgagt gtgtatgtga gtgtggtgag 9000

 ttgcttctgt gcacacactt ttgtttatga gtgtgcatgc aagtgtgatg 9050

 agtgtgaaag tgttcctgta gacatgtttg cctgtgtgtg catatgtgta 9100

 tttgtgggca aacgcagctg tgtctgtgag tgtgagtgtg ccttctgtgt 9150

 gtgtgtgtgc acgtgaatgt ggtgagtgtg tctgtgtgtt aacacaagtg 9200

 tgttcaagag tgtgttatat gagcatataa tgcatgtgtg tattctcgag 9250

 ggctgaggga cccagcccca ccttcaccac ctgctaactg tccccacccc 9300

 cacagcaggc ccagcacagg gatcacattg tcggggtgac ctggcttata 9350

 cttgaagcct ttgagctgga ccctggcttt atccatgagg ccaggctgcg 9400

 tgtccagatg gccacactgg aggatgatgt ggtagaggag gagcgttata 9450

 caggccagtg gagtgagtgg agccagcctg tgtgcttcca ggctccccag 9500

 agacaaggtg ggcactgctg tggctgctgc acttccagcg gagtctgggc 9550

 tgggcgtctt ctcccctgtt cacctcagcc ctgcaccctt tcaccctcct 9600

 gtaagcccct ccccgaggca gccatgcctc agttgacccc cttcctctga 9650

 aggtctgagg tctgtaggga ggacagaaac acctgccaac tctggggctt 9700

 cctgggaacc tgtagttagt ggctgctgtt aggagtgagg gtggcagggc 9750

 tgcacaccag ggctgggctc ctgcctggag gctggacatg acctcagtgt 9800

 ccttaatggg ggctggactg acccttgcgc actgcagtgc tgagatggcc 9850

 cagggacttt atgacccacc ttgtggcaga tgggaagagt gaggcccagg 9900

 agtgtggttc acacaaggtc cttcagcagg tgacacaaac ctccaaggcc 9950

 catcacaagg tccttcagca ggtgacacaa aggtggaagg cccatcacaa 10000

 accttccact ttggcccagg gcactaaagg gcgcaccttt gccaggtggg 10050

 tttgggggga gcctcctggc actgaggctg ctcacagccc tgggcccttc 10100

 ctgtccacag gccctctgat cccaccctgg gggtggccag gcaacaccct 10150

 tgttgctgtg tccatctttc tcctgctgac tggcccgacc tacctcctgt 10200

 tcaagctgtc gcccaggtag gtggctgatg tgtgcgtgtg tgtacatgtg 10250

 tgagcgggca agagtgtgca tgttagtgta tgtgtgcaga tgtgtgactg 10300

 tgtgcatgtg tgagtgtgtg gtgggtgggc catcaagggc cgcccttgtc 10350

 tggttcctcc cctcccctct ccactgcctg gtcctggacg gggtgggctt 10400

 ttcgagtctc caccctggtc cagaagaggg ttctcaagtt gccaggggag 10450

 agcagggaag gggggtctga ggcagaggct gaagataagg gcagcttggt 10500

 cccgaccaga cccagagtca ccgagatcaa gagccggagg tcctagtctc 10550

 ctgcctctgg aggagcttgg tttgttcatt tgttcacatg ttctacgaaa 10600

 ggacagttgg ggcatctggt gtgctcagga ccctgttctc agaacaagat 10650

 ggacaagggc cctccttaaa taaaccgtca cgcctcatgc accacatgtc 10700

 aggttacaag acagggtgca ggggccatgt caggccgcag atgtgaggaa 10750

 gagggtgtgg ggagaggggt gttgggtggg gctaagtggg agggtgcttc 10800

 gcttctcctt ggagcaaagg aaagtgtaaa actgtgtgac acaacctagt 10850

 ttatgttttg aggaatagat tgctgggaca aggggacatg ggggacctgc 10900

 tggaggccaa tgggggccag tgaggtgccc acagggagac gatttgcatg 10950

 agccagtgaa agaagtggag atagagaaaa gtggagagaa ttgcagggtc 11000

 tcatgagggg aaatagaagg gacatgtggg tggatgagat atgagtggtg 11050

 acccctgagg tggggaaatg ggggacagcc ttgcagggag gttggtgaag 11100

 tctatttgga cctgttgggt tggagcccca ggtgacatcc ttgtgggagg 11150

 gtcagtggat ccttggcagc aagtctggtg ctcagggaga cactgggtgg 11200

 ggtgggagcc acagaccttc tgctgatggc aaagacaggg ttcctggagg 11250

 tgctggctcc ctctgtgatc tgaggaccca gctagtaact ccccgttctg 11300

 aacccgccat cgcagctcac gctgtaaagg acgcgcgcct cagtataaat 11350

 cagttctatg cggccgttag gcaaggaggc ccagttgggt cctgccctga 11400

 gagtgggttg gaatgtgatg agatgggaga gaggcagtgg cagggacgag 11450

 gtgggcggac ctcctgctga tggaaggaag ctcagcctct gcagtgacct 11500

 caggccacct gggtcgccat aggcctctga ctggcctctc ttggcctcag 11550

 ggtgaagaga atcttctacc agaacgtgcc ctctccagcg atgttcttcc 11600

 agcccctcta cagtgtacac aatgggaact tccaggtgtg tgcagagacc 11650

 acagaaggac atggggggca ggggttgccc agagctctgg cctgcccaag 11700

 atgttggctt tcatgagggt tggcggccag tatgggaggc ttgtcagtgc 11750

 ttggagcctt ttttgtatat tcagtgaatt tcaatttata cgcgtatctc 11800

 aaatggggaa aaattagctt tattttccat tgctgatttc tttttgttct 11850

 caggtctcta gttccattgt tgattgaaaa aatgtaaatt tctcataact 11900

 tatctctgtc ccctctggtt tgcagctttc tgcacccacc atgtgcctca 11950

 cctcctcctt ctgcgaaggt gtctgtcctg tggccatggg gaagggtctg 12000

 tggtgtgtgt gctgcccttg gggctctcac tgcctctggg ctcctgctct 12050

 gcctggtccc ctggtctccc cggatcacat gatggcacca cagctgagga 12100

 gtgggctctg cacttccccc ccttccaccc atgttgggct cctacagccc 12150

 aggcaccagt gagcaacttg ggggttgcat cagcccctcc cctccctgct 12200

 gggctgttgg ttcatgcccc ctgggtggga ggagggggag agggagagct 12250

 ccagtgagtg gtctctggtt tttcccctca gactcctcac tttgggcaaa 12300

 ggacaagagg cagtgagggc ccctccctgg ggtctgggcc aagctgacca 12350

 ctcttctcca gaatcttccc tccctgtccc cttcacactg tggctccagc 12400

 ttactatgca gaaaaatcct tttctctctc aatgaggagc gtagttttca 12450

 agatttttgt ccaaaaatat aatttgaacc atgaaccggg catctggctc 12500

 ttggcagagt ctccctcttt ccccaaggtg gtagatgtga ctgtcaggag 12550

 cctgggcagc tgacgacaag gctgagcagg tcagattgtg actgtcccct 12600

 ggactgtcat cctgttgcgg gcaccagctg ttccctagag aactaggaca 12650

 cctgccacgg gttatttaga ctgcgggtga ggatctggtg ccataggttg 12700

 gtctccaggg agcactgcag tgatggaggg tgttgtgtgt gtgatgcatg 12750

 ggatggaggc tcctggtccc accaagggaa cagcttcctt ttggaggcgg 12800

 gggcctcctg tggccccaca gaaggatcca ggtctgctgg ccatagccga 12850

 gtgctttgaa agtcaccagt cctgacagcg attcgtgtgt gtgtctgtgt 12900

 gtgtgtgtgt gtgtttatgt gtctgtgtgt gttcgtgtgt gtgtctgtgt 12950

 gtgtgtttgt gtgtgtatgt ctgtgtgtgt gtgtttatgt gtgtgtgtct 13000

 gtatgtgttt aagtctgtgt gtgtttgtgt gtgtgtgtct ctgtgtgtgt 13050

 gtctgtatct gtgtgtgttt gtgtctgtgt gtgtttgtgt gtgtgtctgt 13100

 gtgtgtctgt gtgtgtgtct gtgtgtgtgt ttatgtgtct gtgtatgttt 13150

 gtgtgtgtgt ttgtgtgtgt gtgtttgtgt ttatgtgtgt atgtctgtgt 13200

 gtgtctgtgt gtctgtgtgt gtatgtgtct gtgtgtgttt atgtgtctgt 13250

 gtgtgttcgt gtgtgtgtct gtgtgtgtgt gtttgtgtgt gtatgtctgt 13300

 gtgtgtgtgt gtttatgtgt gtgtgtctgt gtgtgtttat gtctgtgtgt 13350

 gtttgtgtgt gtgtgtctcg tgtgtgtgtg tctgtgtgta tctgtgtgtg 13400

 tttgtgtgtg tgtgtgtctc tgtgtgtgtg tgtgtttgtg tatgtttgtg 13450

 tgtgtgtgtg tgtgtgttgg gaatgcccag tctctgcagc tgctgaaagg 13500

 ccctgaggca catgctgtca ggagctggct ctgtcctggg cagatatcac 13550

 catctgtacc tcggttcagg ctgccgtggg caccaggccc tgtgctgggg 13600

 gagtgctgag gagcctgaag ggactcaggg tcccgtgatg aggctgggct 13650

 ggcacatgga ggaaagacag aatgtccaag acacaggcgc tgcttggcct 13700

 ctgggtgtgg acctcaggag ggcttcctgg aggaggaggg atgctgggct 13750

 tgccagaaag gaggcagctg ctcccaggat gagttctgaa catgctacct 13800

 gagcccttcc ctcctcccgt gctctgttcc agacttggat gggggcccac 13850

 ggggccggtg tgctgttgag ccaggactgt gctggcaccc cacagggagc 13900

 cttggagccc tgcgtccagg aggccactgc actgctcact tgtggcccag 13950

 cgcgtccttg gaaatctgtg gccctggagg aggaacagga gggccctggg 14000

 accaggctcc cggggaacct gagctcagag gatgtgctgc cagcagggtg 14050

 tacggagtgg agggtacaga cgcttgccta tctgccacag gaggactggg 14100

 cccccacgtc cctgactagg ccggctcccc cagactcaga gggcagcagg 14150

 agcagcagca gcagcagcag cagcaacaac aacaactact gtgccttggg 14200

 ctgctatggg ggatggcacc tctcagccct cccaggaaac acacagagct 14250

 ctgggcccat cccagccctg gcctgtggcc tttcttgtga ccatcagggc 14300

 ctggagaccc agcaaggagt tgcctgggtg ctggctggtc actgccagag 14350

 gcctgggctg catgaggacc tccagggcat gttgctccct tctgtcctca 14400

 gcaaggctcg gtcctggaca ttctaggtcc ctgactcgcc agatgcatca 14450

 tgtccatttt gggaaaatgg actgaagttt ctggagccct tgtctgagac 14500

 tgaacctcct gagaaggggc ccctagcagc ggtcagaggt cctgtctgga 14550

 tggaggctgg aggctccccc ctcaacccct ctgctcagtg cctgtgggga 14600

 gcagcctcta ccctcagcat cctggccaca agttcttcct tccattgtcc 14650

 cttttcttta tccctgacct ctctgagaag tggggtgtgg tctctcagct 14700

 gttctgccct cataccctta aagggccagc ctgggcccag tggacacagg 14750

 taaggcacca tgaccacctg gtgtgacctc tctgtgcctt actgaggcac 14800

 ctttctagag attaaaaggg gcttgatggc tgttcccaaa gtgttgatgg 14850

 ctgggagaag gggccagagg aggagtgagg ggtggggttt gtccagccct 14900

 gggctttccg ggctctagag atagcatggt gtaggctcaa tgacagttct 14950

 ggggacagca agttggaggt tcaggggcag cttcaggaca gcaggatgga 15000

 ggctcaggga caattcctgg gaggccagtg ccctcgttcc tccttgtcct 15050

 catcctcccc cttgctccag gaaactgaga gctgagcctg gagcttccag 15100

 acagtcagtg ctgggggtga ccatccagca gtgatggtgg cctgtgaagg 15150

 gtcctgcttc tgtcctcagc ctctcatggg gtgggcttgt ggaggagctg 15200

 tggtctggag agagtggcag ttggagcaga acgtgcctgc gtttgtttcc 15250

 tagggctgtc gtaacaaagt gccacaaaat ggttagctta gaaccacaga 15300

 gatttgttgt ctcacaattc tgaagtccag aagttggaaa taaagatgtt 15350

 ggcagtgttc ccaaccacat gttcttgggc tcccatgaaa cagaagttga 15400

 tattaggcca aggaagcttc ccagacaaga ctttattaag tcttatgccc 15450

 cgaaagtttg ggcagaagag agacggtgca ggaggaagaa ttcttggctg 15500

 actccccaag gggaatgcat tgtggtgtct taaggagggt gacatacata 15550

 atttatgagc tacatgagtg tcattgcaca tatggggtgg agcgaagggt 15600

 gctcagacgc atgctaacac atacgttgca tgatcagaaa atggcagata 15650

 agcccctccc tgggtgagga ctttagtatt atcataagac cagggtcatt 15700

 ctcctggcct tgtgcacaag caggtgatgg agtcaactcc cgtcagtaag 15750

 acttatggcg ggatgctgct tatcttagtt tatttcagac agttggcaag 15800

 gtctggccag cgagtatggc acctggaggg tggtgctgca aggtctagtg 15850

 gtcagcgggc acgtatggaa caatacgtta gtgggggtgg gccgagtccc 15900

 atttatactc tctcagcagg gccatgctcc ctctgaaggc actagggaag 15950

 gattagtttc aggcctctct tcagcttctg ttagtttctt ggcttgtgac 16000

 accaaagctg taatctttct tttgttttgt ttttgtgacg gagttttgct 16050

 cttgttgccc aggctggagt gcaatggcac aatctcggct cactgcaacc 16100

 tcctcctccc aggtttaagc aattcttctg cctcagcctt tggagtagct 16150

 gtgattacaa ggcacctgct accacgcctg gctagttttt gtatttttag 16200

 tagagacggt gtttcgctat gttggccagg ctggtctcaa actcctgata 16250

 tcaagtgatc cgtctgtctc tgcctcccaa agtgttggga ttacaggcat 16300

 gagccaccgt gcctggccaa agttccagtc tttacaggga tttttccttg 16350

 tgtgcatttc tgtgtccaaa tttccccttt ttaaaatcac aataatagtg 16400

 aattaaggct ggccctaacg atttaatctt aacttgatca tctgcaaaga 16450

 cactatttcc atataaggtc acattcacag ctactggggt taggacttca 16500

 acctagaggg cctgacttct ggcccaacac atcatggccc atcccagcat 16550

 gccccatccc cttcctgggt gccccaggca gatcacagga gggcctgact 16600

 gctgggcttt gggctgacat tgggatcatc tgcctagtta gggctgtgac 16650

 cagactgaga taggaggtgg gacctgactc ctgaggcagg gcttgaactc 16700

 tggaccagat tacagactag ctgaaacagg caaaagcacc cctccataag 16750

 acacacccac tggtgccaag tgagtttgcc gttctcatgg taacagctgg 16800

 aaattactgc ccctttccat ggcaatgacc tgaaagttac cacccctttt 16850

 ctagaaattt ctaaataacc tcctccttaa tttgtatata gttacaagtg 16900

 ggtataaata tgtgtgcaga actgcctctg agctgctact ctgggctgac 16950

 tgcctatggg gcatccctgc tccataagga gcagtacctc tgctgccact 17000

 gtgcacagct gcttaaataa aagttgctct ctaataccac cgactcgccc 17050

 ttgaattctt tcctgggtga agc 17073

<210> 2935
<211> 2824
<212> DNA
<213> Homo sapien

<400> 2935
 ggcacgagga ggaagcggag gaaggtgaag taggaccgaa ttcctgtgcc 50

 gaagaggcct gcagtgggag agcaggatgg gggctccgga ggtggcgccc 100

 aggctctgag ctaccctagg tctgcagact agcgggcatt ggccagagac 150

 atggcccagc cactggcctt catcctcgat gtccctgaga ccccagggga 200

 ccagggccag ggccccagcc cctatgatga aagcgaagtg cacgactcct 250

 tccagcagct catccaggag cagagccagt gcacggccca ggaggggctg 300

 gagctgcagc agagagagcg ggaggtgaca ggaagtagcc agcagacact 350

 ctggcggccc gagggcaccc agagcacggc cacactccgc atcctggcca 400

 gcatgcccag ccgcaccatt ggccgcagcc gaggtgccat catctcccag 450

 tactacaacc gcacggtgca gcttcggtgc aggagcagcc ggcccctgct 500

 cgggaacttt gtccgctccg cctggcccag cctccgcctg tacgacctgg 550

 agctggaccc cacggccctg gaggaggagg agaagcagag cctcctggtg 600

 aaggagttcc agagcctggc agtggcacag cgggaccaca tgcttcgcgg 650

 gatgccctta agcctggctg agaaacgcag cctgcgagag aagagcagga 700

 ccccgagggg gaagtggagg ggccagccgg gcagcggcgg ggtctgctcc 750

 tgctgtggcc ggctcagata tgcctgcgtg ctggccttgc acagcctggg 800

 cctggcgctg ctctccgccc tgcaggccct gatgccgtgg cgctacgccc 850

 tgaagcgcat cgggggccag ttcggctcca gcgtgctctc ctacttcctc 900

 tttctcaaga ccctgctggc tttcaatgcc ctcctgctgc tgctgctggt 950

 ggccttcatc atgggccctc aggtcgcctt cccacccgcc ctgccgggcc 1000

 ctgcccccgt ctgcacaggc ctggagctcc tcacaggcgc gggttgcttc 1050

 acccacaccg tcatgtacta cggccactac agtaacgcca cgctgaacca 1100

 gccgtgtggc agccccctgg atggcagcca gtgcacaccc agggtgggtg 1150

 gcctgcccta caacatgccc ctggcctacc tctccactgt gggcgtgagc 1200

 ttctttatca cctgcatcac cctggtgtac agcatggctc actctttcgg 1250

 ggagagctac cgggtgggca gcacctctgg catccacgcc atcaccgtct 1300

 tctgctcctg ggactacaag gtgacgcaga agcgggcctc ccgcctccag 1350

 caggacaata ttcgcacccg gctgaaggag ctgctggccg agtggcagct 1400

 gcggcacagc cccaggagcg tgtgcgggag gctgcggcag gcggctgtgc 1450

 tggggcttgt gtggctgctg tgtctgggga ccgcgctggg ctgcgccgtg 1500

 gccgtccacg tcttctcgga gttcatgatc cagagtccag aggctgctgg 1550

 ccaggaggct gtgctgctgg tcctgcccct ggtggttggc ctcctcaacc 1600

 tgggggcccc ctacctgtgc cgtgtcctgg ccgccctgga gccgcatgac 1650

 tccccggtac tggaggtgta cgtggccatc tgcaggaacc tcatcctcaa 1700

 gctggccatc ctggggacac tgtgctacca ctggctgggc cgcagggtgg 1750

 gcgtcctgca gggccagtgc tgggaggatt ttgtgggcca ggagctgtac 1800

 cggttcctgg tgatggactt cgtcctcatg ttgctggaca cgctttttgg 1850

 ggaactggtg tggaggatta tctccgagaa gaagctgaag aggaggcgga 1900

 agccggagtt tgacattgcc cggaatgtcc tggagctgat ttatgggcag 1950

 actctgacct ggctgggggt gctcttctcg cccctcctcc ccgccgtgca 2000

 gatcatcaag ctgctgctcg tcttctatgt caagaagacc agccttctgg 2050

 ccaactgcca ggcgccgcgc cggccctggc tggcctcaca catgagcacc 2100

 gtcttcctca cgctgctctg cttccccgcc ttcctgggcg ccgctgtctt 2150

 cctctgctac gccgtctggc aggtgaagcc ctcgagcacc tgcggcccct 2200

 tccggaccct ggacaccatg tacgaggccg gcagggtgtg ggtgcgccac 2250

 ctggaggcgg caggccccag ggtctcctgg ctgccctggg tgcaccggta 2300

 cctgatggaa aacaccttct ttgtcttcct ggtgtcagcc ctgctgctgg 2350

 ccgtgatcta cctcaacatc caggtggtgc ggggccagcg caaggtcatc 2400

 tgcctgctca aggagcagat cagcaatgag ggtgaggaca aaatcttctt 2450

 aatcaacaag cttcactcca tctacgagag gaaggagagg gaggagagga 2500

 gcagggttgg gacaaccgag gaggctgcgg caccccctgc cctgctcaca 2550

 gatgaacagg atgcctaggg ggacggcgat gggcctcacg ggcccgccca 2600

 gcaccctgag accacactgt tgcctcccag tgaccctgct gggacaccag 2650

 gacaaggaag acagtttcgc ctctcgaaag ccgcagctgc gcctaggctg 2700

 gagctggaag ggtgggtgaa tccggcttgg gcatccccaa tgaactctgc 2750

 cctgcctggg actctattta ttctgattaa aggggttttg caaatgggaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaa 2824

<210> 2936
<211> 805
<212> PRT
<213> Homo sapien

<400> 2936
 Met Ala Gln Pro Leu Ala Phe Ile Leu Asp Val Pro Glu Thr Pro
   1               5                  10                  15

 Gly Asp Gln Gly Gln Gly Pro Ser Pro Tyr Asp Glu Ser Glu Val
                  20                  25                  30

 His Asp Ser Phe Gln Gln Leu Ile Gln Glu Gln Ser Gln Cys Thr
                  35                  40                  45

 Ala Gln Glu Gly Leu Glu Leu Gln Gln Arg Glu Arg Glu Val Thr
                  50                  55                  60

 Gly Ser Ser Gln Gln Thr Leu Trp Arg Pro Glu Gly Thr Gln Ser
                  65                  70                  75

 Thr Ala Thr Leu Arg Ile Leu Ala Ser Met Pro Ser Arg Thr Ile
                  80                  85                  90

 Gly Arg Ser Arg Gly Ala Ile Ile Ser Gln Tyr Tyr Asn Arg Thr
                  95                 100                 105

 Val Gln Leu Arg Cys Arg Ser Ser Arg Pro Leu Leu Gly Asn Phe
                 110                 115                 120

 Val Arg Ser Ala Trp Pro Ser Leu Arg Leu Tyr Asp Leu Glu Leu
                 125                 130                 135

 Asp Pro Thr Ala Leu Glu Glu Glu Glu Lys Gln Ser Leu Leu Val
                 140                 145                 150

 Lys Glu Phe Gln Ser Leu Ala Val Ala Gln Arg Asp His Met Leu
                 155                 160                 165

 Arg Gly Met Pro Leu Ser Leu Ala Glu Lys Arg Ser Leu Arg Glu
                 170                 175                 180

 Lys Ser Arg Thr Pro Arg Gly Lys Trp Arg Gly Gln Pro Gly Ser
                 185                 190                 195

 Gly Gly Val Cys Ser Cys Cys Gly Arg Leu Arg Tyr Ala Cys Val
                 200                 205                 210

 Leu Ala Leu His Ser Leu Gly Leu Ala Leu Leu Ser Ala Leu Gln
                 215                 220                 225

 Ala Leu Met Pro Trp Arg Tyr Ala Leu Lys Arg Ile Gly Gly Gln
                 230                 235                 240

 Phe Gly Ser Ser Val Leu Ser Tyr Phe Leu Phe Leu Lys Thr Leu
                 245                 250                 255

 Leu Ala Phe Asn Ala Leu Leu Leu Leu Leu Leu Val Ala Phe Ile
                 260                 265                 270

 Met Gly Pro Gln Val Ala Phe Pro Pro Ala Leu Pro Gly Pro Ala
                 275                 280                 285

 Pro Val Cys Thr Gly Leu Glu Leu Leu Thr Gly Ala Gly Cys Phe
                 290                 295                 300

 Thr His Thr Val Met Tyr Tyr Gly His Tyr Ser Asn Ala Thr Leu
                 305                 310                 315

 Asn Gln Pro Cys Gly Ser Pro Leu Asp Gly Ser Gln Cys Thr Pro
                 320                 325                 330

 Arg Val Gly Gly Leu Pro Tyr Asn Met Pro Leu Ala Tyr Leu Ser
                 335                 340                 345

 Thr Val Gly Val Ser Phe Phe Ile Thr Cys Ile Thr Leu Val Tyr
                 350                 355                 360

 Ser Met Ala His Ser Phe Gly Glu Ser Tyr Arg Val Gly Ser Thr
                 365                 370                 375

 Ser Gly Ile His Ala Ile Thr Val Phe Cys Ser Trp Asp Tyr Lys
                 380                 385                 390

 Val Thr Gln Lys Arg Ala Ser Arg Leu Gln Gln Asp Asn Ile Arg
                 395                 400                 405

 Thr Arg Leu Lys Glu Leu Leu Ala Glu Trp Gln Leu Arg His Ser
                 410                 415                 420

 Pro Arg Ser Val Cys Gly Arg Leu Arg Gln Ala Ala Val Leu Gly
                 425                 430                 435

 Leu Val Trp Leu Leu Cys Leu Gly Thr Ala Leu Gly Cys Ala Val
                 440                 445                 450

 Ala Val His Val Phe Ser Glu Phe Met Ile Gln Ser Pro Glu Ala
                 455                 460                 465

 Ala Gly Gln Glu Ala Val Leu Leu Val Leu Pro Leu Val Val Gly
                 470                 475                 480

 Leu Leu Asn Leu Gly Ala Pro Tyr Leu Cys Arg Val Leu Ala Ala
                 485                 490                 495

 Leu Glu Pro His Asp Ser Pro Val Leu Glu Val Tyr Val Ala Ile
                 500                 505                 510

 Cys Arg Asn Leu Ile Leu Lys Leu Ala Ile Leu Gly Thr Leu Cys
                 515                 520                 525

 Tyr His Trp Leu Gly Arg Arg Val Gly Val Leu Gln Gly Gln Cys
                 530                 535                 540

 Trp Glu Asp Phe Val Gly Gln Glu Leu Tyr Arg Phe Leu Val Met
                 545                 550                 555

 Asp Phe Val Leu Met Leu Leu Asp Thr Leu Phe Gly Glu Leu Val
                 560                 565                 570

 Trp Arg Ile Ile Ser Glu Lys Lys Leu Lys Arg Arg Arg Lys Pro
                 575                 580                 585

 Glu Phe Asp Ile Ala Arg Asn Val Leu Glu Leu Ile Tyr Gly Gln
                 590                 595                 600

 Thr Leu Thr Trp Leu Gly Val Leu Phe Ser Pro Leu Leu Pro Ala
                 605                 610                 615

 Val Gln Ile Ile Lys Leu Leu Leu Val Phe Tyr Val Lys Lys Thr
                 620                 625                 630

 Ser Leu Leu Ala Asn Cys Gln Ala Pro Arg Arg Pro Trp Leu Ala
                 635                 640                 645

 Ser His Met Ser Thr Val Phe Leu Thr Leu Leu Cys Phe Pro Ala
                 650                 655                 660

 Phe Leu Gly Ala Ala Val Phe Leu Cys Tyr Ala Val Trp Gln Val
                 665                 670                 675

 Lys Pro Ser Ser Thr Cys Gly Pro Phe Arg Thr Leu Asp Thr Met
                 680                 685                 690

 Tyr Glu Ala Gly Arg Val Trp Val Arg His Leu Glu Ala Ala Gly
                 695                 700                 705

 Pro Arg Val Ser Trp Leu Pro Trp Val His Arg Tyr Leu Met Glu
                 710                 715                 720

 Asn Thr Phe Phe Val Phe Leu Val Ser Ala Leu Leu Leu Ala Val
                 725                 730                 735

 Ile Tyr Leu Asn Ile Gln Val Val Arg Gly Gln Arg Lys Val Ile
                 740                 745                 750

 Cys Leu Leu Lys Glu Gln Ile Ser Asn Glu Gly Glu Asp Lys Ile
                 755                 760                 765

 Phe Leu Ile Asn Lys Leu His Ser Ile Tyr Glu Arg Lys Glu Arg
                 770                 775                 780

 Glu Glu Arg Ser Arg Val Gly Thr Thr Glu Glu Ala Ala Ala Pro
                 785                 790                 795

 Pro Ala Leu Leu Thr Asp Glu Gln Asp Ala
                 800                 805

<210> 2937
<211> 4295
<212> DNA
<213> Homo sapien

<400> 2937
 gaggaggttc ctgtagggcg gcacaaccag ggagggcgtg gaagctctgc 50

 atcccttctc ccataccttg ctctacacat ctcttcatct gtatcctctg 100

 cagcatcctt gatgataaac cagtaaatat gagttttgat catcctgaga 150

 aaaatgggcc ttggcctgca gacccaataa accttccctc ccatggataa 200

 tagtgctaat tcctgaggac ctgaagggcc tgccgcccct gggggattag 250

 ccagaagcag gcttgttttc ctgctcagaa caaagtgact tccctgaaca 300

 catcttcatt atgattcaca ccaacctgaa gaaaaagttc agctgctgcg 350

 tcctggtctt tcttctgttt gcagtcatct gtgtgtggaa ggaaaagaag 400

 aaagggagtt actatgattc ctttaaattg caaaccaagg aattccaggt 450

 gttaaagagt ctggggaaat tggccatggg gtctgattcc cagtctgtat 500

 cctcaagcag cacccaggac ccccacaggg gccgccagac cctcggcagt 550

 ctcagaggcc tagccaaggc caaaccagag gcctccttcc aggtgtggaa 600

 caaggacagc tcttccaaaa accttatccc taggctgcaa aagatctgga 650

 agaattacct aagcatgaac aagtacaaag tgtcctacaa ggggccagga 700

 ccaggcatca agttcagtgc agaggccctg cgctgccacc tccgggacca 750

 tgtgaatgta tccatggtag aggtcacaga ttttcccttc aatacctctg 800

 aatgggaggg ttatctgccc aaggagagca ttaggaccaa ggctgggcct 850

 tggggcaggt gtgctgttgt gtcgtcagcg ggatctctga agtcctccca 900

 actaggcaga gaaatcgatg atcatgacgc agtcctgagg tttaatgggg 950

 cacccacagc caacttccaa caagatgtgg gcacaaaaac taccattcgc 1000

 ctgatgaact ctcagttggt taccacagag aagcgcttcc tcaaagacag 1050

 tttgtacaat gaaggaatcc taattgtatg ggacccatct gtataccact 1100

 cagatatccc aaagtggtac cagaatccgg attataattt ctttaacaac 1150

 tacaagactt atcgtaagct gcaccccaat cagccctttt acatcctcaa 1200

 gccccagatg ccttgggagc tatgggacat tcttcaagaa atctccccag 1250

 aagagattca gccaaacccc ccatcctctg ggatgcttgg tatcatcatc 1300

 atgatgacgc tgtgtgacca ggtggatatt tatgagttcc tcccatccaa 1350

 gcgcaagact gacgtgtgct actactacca gaagttcttc gatagtgcct 1400

 gcacgatggg tgcctaccac ccgctgctct atgagaagaa tttggtgaag 1450

 catctcaacc agggcacaga tgaggacatc tacctgcttg gaaaagccac 1500

 actgcctggc ttccggacca ttcactgcta agcacaggct cctcactctt 1550

 ctccatcagg cattaaatga atggtctctt ggccacccca gcctgggaag 1600

 aacattttcc tgaacaattc cagcctgctc cttttactct aggggcctct 1650

 gtcagcaaga ccatggggac ttcaagagcc tgtggtcagg aaatcaggtc 1700

 cagccttccc tgtagccaga cagtttatga gcccagagcc tcctgccaca 1750

 cacatgcaca catatctagc attctttcca gacagcatcc tccccgcctt 1800

 ccaccttggt agatgcaagg tctatctctc ccatcagggc tgccaaagct 1850

 gggctttgtt tttcccagca gaatgatgcc attctcacaa accaatgctc 1900

 tatattgctt gaagtctgca tctaaatatt gatttcacgt tttaaagaaa 1950

 ttctcttaaa ttacaattgt gcccaatgca gggtggctct ggggggcaag 2000

 taggtggtac aggggattgg aaacatgctc cgcgcctcca gagaaaagtt 2050

 gctcccgagg tccatgcccc tggaacgtgt tcctatcact ctggctggtt 2100

 gggctggtcc ttagactggg tgcttatgat taaagggtct tggttagccc 2150

 actttccctc tccatgtgga gatggaaggt agagaaggat acagtgtcta 2200

 tcctcaagtt gctacggttc agtgagagag gcagacatct gaacaggcag 2250

 gtaggattca gtgtgctcag tgcactgggg atttggagag agatgggctt 2300

 gctctctctg tgcacccagg agggccacgc acttaaaact gtgtttgtgg 2350

 atcagagaag gctttatagc acagggggca ttcagatgag tcttagagga 2400

 agagaagaaa catggcaagc agattacatc tgagccgttt gaattgtgtt 2450

 tttctttctt cccatgttta ttttctaaga tctacctgaa cttagagact 2500

 caagatattt ttttaggaaa cctcctaccc atgtctgagg tagcaagtgc 2550

 agcctcacga cagataccag gcaatccaga gccacaaaac gtgattcctc 2600

 caggctctgc ctggcctgac cctgtcctgt cagctgggtt tacataccag 2650

 tcccattctt ccttttcaat acctaccccc aaatcttctc ctaaccacca 2700

 tctgtttttt ttttttaaag cattttttgc tttaaaagca tcctgacccc 2750

 aatttctttg agctcacggg ccttttgctg aaggtctctc agggtgtagt 2800

 ggtgtggctc tctggactta acgtcactct cagaggtcag aaccttggag 2850

 atcagaactg attctcacca ggtgtgagag gtgtggtagc agattgcaat 2900

 gctctgcacc tcttccttgc aagtgagcaa cttcaggctc tctgggcaga 2950

 ggctggccca ctgtagtttg cagacatgct ctccagatgg ttttactaag 3000

 tcccctctcc ctgataggga atcctgctgg accagcgcag ccctggtgtg 3050

 gagaggttaa aagacttgca caggatcacc aagtcatgct gtagagccag 3100

 gattcctaga cccagggctc tgcactctca aggctggccc catgtgctca 3150

 aggggatcta atgtttgggc tccaaactaa ccatctcgga gctgggctcc 3200

 tcatttactg ccaaaccctc agcttatgta gctagaaagg gccctggagt 3250

 gagaaagcct ggattttcaa attgatgctc ccctactgac tagctgtgcc 3300

 actctgggca aatgctcttc cttgagcctg tttccacacc tgtaaagtgg 3350

 ggatgatgat cctatctcac tgcttttgtg aggattacag gaaagcacct 3400

 gtcctggctc tgtacctggc acgtagtagg tgctcagttc atgctggttt 3450

 ccttcctgcc tttagtaggg acctgctctg tgctcacacc tcggctgcat 3500

 gcaccctgct gtgacggagg ctagtgtgga agaggtcctg tcctcaggga 3550

 attaactgtc ttattgggag acaacaactg tcctccttgg aacacccaag 3600

 aaaccatgca aagcagtgga caacacagaa cacgccctcc tcctcgctgc 3650

 ctgcagctcc aatctgattc tgcttgggaa tgggcggagc acgtgggctg 3700

 cttaactgct gtataggaca agccccttac ccctctctgg gcccatgaat 3750

 tcctggcttg gtttatgttc tgatttgaca cactgatttt aatcttcgaa 3800

 tcatgacact gagtgcagag gaggtggcat tccgacagca ggacatacat 3850

 gttggtgtga agactgggac gacactgggt agaatctagt ttttaattat 3900

 tattaatata aaggatcaaa ttaatttaaa tatgattctg aagtctacag 3950

 aacttttagt tctgtgctgt ctatgtggac actttggtaa aatgcaaatt 4000

 atgatatgga cgttatcatt ggtctggtga gatgtttcat atttgtgaca 4050

 gttaatttaa aaattatgag ttaatgctgc ctgtgtctat ggggttctgt 4100

 cttctttgat agccatctat tcatctggat catgggaccc tctctaatcc 4150

 ttccaccaat caaataagct attgctattg gtttggagtt gagatatcag 4200

 tctcggaaac ttctgaaaaa tgctaataat tacccaagga ttatgtcaaa 4250

 ttttaaaata aatgtgtgtg tgtttcttta aaaaaaaaaa aaaaa 4295

<210> 2938
<211> 406
<212> PRT
<213> Homo sapien

<400> 2938
 Met Ile His Thr Asn Leu Lys Lys Lys Phe Ser Cys Cys Val Leu
   1               5                  10                  15

 Val Phe Leu Leu Phe Ala Val Ile Cys Val Trp Lys Glu Lys Lys
                  20                  25                  30

 Lys Gly Ser Tyr Tyr Asp Ser Phe Lys Leu Gln Thr Lys Glu Phe
                  35                  40                  45

 Gln Val Leu Lys Ser Leu Gly Lys Leu Ala Met Gly Ser Asp Ser
                  50                  55                  60

 Gln Ser Val Ser Ser Ser Ser Thr Gln Asp Pro His Arg Gly Arg
                  65                  70                  75

 Gln Thr Leu Gly Ser Leu Arg Gly Leu Ala Lys Ala Lys Pro Glu
                  80                  85                  90

 Ala Ser Phe Gln Val Trp Asn Lys Asp Ser Ser Ser Lys Asn Leu
                  95                 100                 105

 Ile Pro Arg Leu Gln Lys Ile Trp Lys Asn Tyr Leu Ser Met Asn
                 110                 115                 120

 Lys Tyr Lys Val Ser Tyr Lys Gly Pro Gly Pro Gly Ile Lys Phe
                 125                 130                 135

 Ser Ala Glu Ala Leu Arg Cys His Leu Arg Asp His Val Asn Val
                 140                 145                 150

 Ser Met Val Glu Val Thr Asp Phe Pro Phe Asn Thr Ser Glu Trp
                 155                 160                 165

 Glu Gly Tyr Leu Pro Lys Glu Ser Ile Arg Thr Lys Ala Gly Pro
                 170                 175                 180

 Trp Gly Arg Cys Ala Val Val Ser Ser Ala Gly Ser Leu Lys Ser
                 185                 190                 195

 Ser Gln Leu Gly Arg Glu Ile Asp Asp His Asp Ala Val Leu Arg
                 200                 205                 210

 Phe Asn Gly Ala Pro Thr Ala Asn Phe Gln Gln Asp Val Gly Thr
                 215                 220                 225

 Lys Thr Thr Ile Arg Leu Met Asn Ser Gln Leu Val Thr Thr Glu
                 230                 235                 240

 Lys Arg Phe Leu Lys Asp Ser Leu Tyr Asn Glu Gly Ile Leu Ile
                 245                 250                 255

 Val Trp Asp Pro Ser Val Tyr His Ser Asp Ile Pro Lys Trp Tyr
                 260                 265                 270

 Gln Asn Pro Asp Tyr Asn Phe Phe Asn Asn Tyr Lys Thr Tyr Arg
                 275                 280                 285

 Lys Leu His Pro Asn Gln Pro Phe Tyr Ile Leu Lys Pro Gln Met
                 290                 295                 300

 Pro Trp Glu Leu Trp Asp Ile Leu Gln Glu Ile Ser Pro Glu Glu
                 305                 310                 315

 Ile Gln Pro Asn Pro Pro Ser Ser Gly Met Leu Gly Ile Ile Ile
                 320                 325                 330

 Met Met Thr Leu Cys Asp Gln Val Asp Ile Tyr Glu Phe Leu Pro
                 335                 340                 345

 Ser Lys Arg Lys Thr Asp Val Cys Tyr Tyr Tyr Gln Lys Phe Phe
                 350                 355                 360

 Asp Ser Ala Cys Thr Met Gly Ala Tyr His Pro Leu Leu Tyr Glu
                 365                 370                 375

 Lys Asn Leu Val Lys His Leu Asn Gln Gly Thr Asp Glu Asp Ile
                 380                 385                 390

 Tyr Leu Leu Gly Lys Ala Thr Leu Pro Gly Phe Arg Thr Ile His
                 395                 400                 405

 Cys


<210> 2939
<211> 2754
<212> DNA
<213> Homo sapien

<400> 2939
 agcggggggg taacgcgggg ccgccaggtg acagctaatg gcggcggccg 50

 cctgaggcgg gcgggcggta tagagcgggc ggcaggaggc aagcagcgaa 100

 accttcccgg ccgccgctcc cgtcccgacg gcggcttccc caaggcggca 150

 ggactcggcg cgccatggac aggccggcgg cggcggcggc ggcgggctgc 200

 gagggcggcg ggggcccgaa cccggggccg gcgggcggca ggaggcctcc 250

 tcgggccgcg gggggcgcca ccgccggctc ccggcagccc agcgtggaga 300

 ccctggacag tcccacagga tcacatgttg aatggtgtaa acagcttata 350

 gctgctacaa tttctagtca gatttcaggt tcagtgacat cagaaaatgt 400

 gtccagagat tacaaggctc taagggatgg aaataagctg gcacagatgg 450

 aagaggctcc acttttccca ggagaatcaa ttaaagccat tgtgaaagat 500

 gtcatgtata tctgcccatt tatgggagca gtgagtggaa ccctgacagt 550

 gacggacttt aagctgtact tcaaaaatgt cgagagggac ccgcatttta 600

 tccttgatgt tccccttgga gtgatcagca gagtggagaa gattggagca 650

 cagagccatg gagacaattc ctgtggtata gagatagtgt gcaaggatat 700

 gaggaacttg cggcttgctt ataaacagga agaacagagt aaactaggga 750

 tatttgaaaa cctcaacaaa catgcatttc ctctttctaa cggacaggca 800

 ctatttgcat tcagctataa agaaaaattt ccaattaatg gctggaaagt 850

 ttatgatcca gtatctgaat ataagagaca gggcttgcca aatgagagtt 900

 ggaaaatatc caaaataaac agtaattatg agttctgtga cacctaccct 950

 gccatcattg ttgtgccaac tagtgtaaaa gatgatgacc tttcaaaagt 1000

 ggcagctttt cgagcaaaag gcagagtccc tgtgttgtca tggattcatc 1050

 cggaaagtca agcaacgatt acccgttgca gccagccact tgtgggtccc 1100

 aatgataagc gctgcaaaga ggatgaaaaa tacttgcaaa caataatgga 1150

 tgctaacgca cagtcacaca agcttatcat ctttgatgct cgacaaaaca 1200

 gtgtcgctga taccaacaag acaaagggtg gaggatatga aagtgaaagt 1250

 gcttacccaa atgcagaact tgtgttcttg gagatccaca acattcatgt 1300

 catgcgagag tcactacgca aattaaaaga gattgtgtac ccttcgatcg 1350

 atgaggcgcg gtggctctcc aatgtggatg ggacgcattg gctggaatat 1400

 ataaggatgc tgcttgctgg ggcagtaaga attgctgata aaatagaatc 1450

 tgggaaaaca tctgtggtgg tgcattgcag cgacggttgg gaccgaacag 1500

 cccagctcac atctctggct atgctaatgt tggacagtta ctacaggacc 1550

 attaaaggat ttgaaactct cgtagaaaag gagtggataa gctttggaca 1600

 caggtttgca ctgcgagtgg gccatggtaa tgacaaccat gcggatgctg 1650

 accgatctcc catatttctg cagtttgttg attgtgtttg gcaaatgaca 1700

 aggcagtttc cttcagcatt cgagtttaat gagctattct tgattacaat 1750

 tttggatcac ctttatagct gtctttttgg gacctttttg tgcaactgtg 1800

 aacagcagcg attcaaagag gatgtatata caaagacgat atctttatgg 1850

 tcgtatatca atagccagct agacgagttt tctaatccct tctttgtgaa 1900

 ttatgaaaac cacgtgttat atcctgttgc tagtctgagt catttggaat 1950

 tgtgggtaaa ttattatgta cgatggaatc cacggatgag acctcagatg 2000

 cccattcacc agaatctcaa ggagctgctg gccgtcaggg cggagctgca 2050

 gaagcgtgtg gagggcctac agcgggaggt ggccacgcgc gccgtctcat 2100

 cctcatctga gcggggctcc tcgccctccc actccgccac ctccgtccac 2150

 acctcggtct gatgggcgag aaatatgtaa tcccctggct gactaggact 2200

 gttaaacata gtgtggactg gatgatgcct tcgacaaacc agagaagcca 2250

 agttgggggg agctggtgcc tggagtgggc cctgtgcacc tcacctggcg 2300

 gaggctgggg ggggctctgt cagcaggacc ctagaggaga ctctcattcg 2350

 attttaaaga agcacaacgg gtcattttcc tttgtatgtt cctagcgcag 2400

 aactgtttct aaaacaactt gaagtatagt tttgttatct aagcaatttt 2450

 tgttttaagt aagtaagtgt actagaatgc gaagccgtta tggttcaggt 2500

 ttttaaaaac tggtacagta ttgtatttgt ctcatctgtt gcactgtatt 2550

 tcaatcatct gtaattaaaa tgatcatatg tttgctccct ggtctttttt 2600

 aagtaagtaa gtaagtatct tagtagattt ttcctttgag gaaaatcggt 2650

 aataaaataa catggattga atgtttactg tgcgtcaagc acagttaata 2700

 tatgatgatg taaagtaact aactttatgt gatttaattc attcagtaaa 2750

 ttgt 2754

<210> 2940
<211> 665
<212> PRT
<213> Homo sapien

<400> 2940
 Met Asp Arg Pro Ala Ala Ala Ala Ala Ala Gly Cys Glu Gly Gly
   1               5                  10                  15

 Gly Gly Pro Asn Pro Gly Pro Ala Gly Gly Arg Arg Pro Pro Arg
                  20                  25                  30

 Ala Ala Gly Gly Ala Thr Ala Gly Ser Arg Gln Pro Ser Val Glu
                  35                  40                  45

 Thr Leu Asp Ser Pro Thr Gly Ser His Val Glu Trp Cys Lys Gln
                  50                  55                  60

 Leu Ile Ala Ala Thr Ile Ser Ser Gln Ile Ser Gly Ser Val Thr
                  65                  70                  75

 Ser Glu Asn Val Ser Arg Asp Tyr Lys Ala Leu Arg Asp Gly Asn
                  80                  85                  90

 Lys Leu Ala Gln Met Glu Glu Ala Pro Leu Phe Pro Gly Glu Ser
                  95                 100                 105

 Ile Lys Ala Ile Val Lys Asp Val Met Tyr Ile Cys Pro Phe Met
                 110                 115                 120

 Gly Ala Val Ser Gly Thr Leu Thr Val Thr Asp Phe Lys Leu Tyr
                 125                 130                 135

 Phe Lys Asn Val Glu Arg Asp Pro His Phe Ile Leu Asp Val Pro
                 140                 145                 150

 Leu Gly Val Ile Ser Arg Val Glu Lys Ile Gly Ala Gln Ser His
                 155                 160                 165

 Gly Asp Asn Ser Cys Gly Ile Glu Ile Val Cys Lys Asp Met Arg
                 170                 175                 180

 Asn Leu Arg Leu Ala Tyr Lys Gln Glu Glu Gln Ser Lys Leu Gly
                 185                 190                 195

 Ile Phe Glu Asn Leu Asn Lys His Ala Phe Pro Leu Ser Asn Gly
                 200                 205                 210

 Gln Ala Leu Phe Ala Phe Ser Tyr Lys Glu Lys Phe Pro Ile Asn
                 215                 220                 225

 Gly Trp Lys Val Tyr Asp Pro Val Ser Glu Tyr Lys Arg Gln Gly
                 230                 235                 240

 Leu Pro Asn Glu Ser Trp Lys Ile Ser Lys Ile Asn Ser Asn Tyr
                 245                 250                 255

 Glu Phe Cys Asp Thr Tyr Pro Ala Ile Ile Val Val Pro Thr Ser
                 260                 265                 270

 Val Lys Asp Asp Asp Leu Ser Lys Val Ala Ala Phe Arg Ala Lys
                 275                 280                 285

 Gly Arg Val Pro Val Leu Ser Trp Ile His Pro Glu Ser Gln Ala
                 290                 295                 300

 Thr Ile Thr Arg Cys Ser Gln Pro Leu Val Gly Pro Asn Asp Lys
                 305                 310                 315

 Arg Cys Lys Glu Asp Glu Lys Tyr Leu Gln Thr Ile Met Asp Ala
                 320                 325                 330

 Asn Ala Gln Ser His Lys Leu Ile Ile Phe Asp Ala Arg Gln Asn
                 335                 340                 345

 Ser Val Ala Asp Thr Asn Lys Thr Lys Gly Gly Gly Tyr Glu Ser
                 350                 355                 360

 Glu Ser Ala Tyr Pro Asn Ala Glu Leu Val Phe Leu Glu Ile His
                 365                 370                 375

 Asn Ile His Val Met Arg Glu Ser Leu Arg Lys Leu Lys Glu Ile
                 380                 385                 390

 Val Tyr Pro Ser Ile Asp Glu Ala Arg Trp Leu Ser Asn Val Asp
                 395                 400                 405

 Gly Thr His Trp Leu Glu Tyr Ile Arg Met Leu Leu Ala Gly Ala
                 410                 415                 420

 Val Arg Ile Ala Asp Lys Ile Glu Ser Gly Lys Thr Ser Val Val
                 425                 430                 435

 Val His Cys Ser Asp Gly Trp Asp Arg Thr Ala Gln Leu Thr Ser
                 440                 445                 450

 Leu Ala Met Leu Met Leu Asp Ser Tyr Tyr Arg Thr Ile Lys Gly
                 455                 460                 465

 Phe Glu Thr Leu Val Glu Lys Glu Trp Ile Ser Phe Gly His Arg
                 470                 475                 480

 Phe Ala Leu Arg Val Gly His Gly Asn Asp Asn His Ala Asp Ala
                 485                 490                 495

 Asp Arg Ser Pro Ile Phe Leu Gln Phe Val Asp Cys Val Trp Gln
                 500                 505                 510

 Met Thr Arg Gln Phe Pro Ser Ala Phe Glu Phe Asn Glu Leu Phe
                 515                 520                 525

 Leu Ile Thr Ile Leu Asp His Leu Tyr Ser Cys Leu Phe Gly Thr
                 530                 535                 540

 Phe Leu Cys Asn Cys Glu Gln Gln Arg Phe Lys Glu Asp Val Tyr
                 545                 550                 555

 Thr Lys Thr Ile Ser Leu Trp Ser Tyr Ile Asn Ser Gln Leu Asp
                 560                 565                 570

 Glu Phe Ser Asn Pro Phe Phe Val Asn Tyr Glu Asn His Val Leu
                 575                 580                 585

 Tyr Pro Val Ala Ser Leu Ser His Leu Glu Leu Trp Val Asn Tyr
                 590                 595                 600

 Tyr Val Arg Trp Asn Pro Arg Met Arg Pro Gln Met Pro Ile His
                 605                 610                 615

 Gln Asn Leu Lys Glu Leu Leu Ala Val Arg Ala Glu Leu Gln Lys
                 620                 625                 630

 Arg Val Glu Gly Leu Gln Arg Glu Val Ala Thr Arg Ala Val Ser
                 635                 640                 645

 Ser Ser Ser Glu Arg Gly Ser Ser Pro Ser His Ser Ala Thr Ser
                 650                 655                 660

 Val His Thr Ser Val
                 665

<210> 2941
<211> 3137
<212> DNA
<213> Homo sapien

<400> 2941
 gcggagcgtg tgagcagtac tgcggcctcc tctcctctcc taacctcgct 50

 ctcgcggcct acctttaccc gcccgcctgc tcggcgacca gcggggatcc 100

 tcccccagcc gcaagtccac gaagaaagca acgaatgaaa attatgaaga 150

 caacgagaag tcagactcct ccgggtcgcg ctccagctgc ttcggcttcg 200

 tcgcctactc tgtgaactcc ggggagagat ctcgagtcaa gattaagacc 250

 ttaacccacc aacctgcctg ttcggacacc ccccgggccg gccgctgtct 300

 gtccccttct ccatcgccct ctcccagaaa gctccggtgc ttggaccagc 350

 tagagtctga gaaagaggag aggcgcgaac gccactccaa aaagagaagg 400

 gttaaagagg gcaaccctaa cgatacgctt gactttctgt ggctgggaac 450

 accttccacc atgaccacct cagcaagttc ccacttaaat aaaggcatca 500

 agcaggtgta catgtccctg cctcagggtg agaaagtcca ggccatgtat 550

 atctggatcg atggtactgg agaaggactg cgctgcaaga cccggaccct 600

 ggacagtgag cccaagtgtg tggaagagtt gcctgagtgg aatttcgatg 650

 gctccagtac tttacagtct gagggttcca acagtgacat gtatctcgtg 700

 cctgctgcca tgtttcggga ccccttccgt aaggacccta acaagctggt 750

 gttatgtgaa gttttcaagt acaatcgaag gcctgcagag accaatttga 800

 ggcacacctg taaacggata atggacatgg tgagcaacca gcacccctgg 850

 tttggcatgg agcaggagta taccctcatg gggacagatg ggcacccctt 900

 tggttggcct tccaacggct tcccagggcc ccagggtcca tattactgtg 950

 gtgtgggagc agacagagcc tatggcaggg acatcgtgga ggcccattac 1000

 cgggcctgct tgtatgctgg agtcaagatt gcggggacta atgccgaggt 1050

 catgcctgcc cagtgggaat ttcagattgg accttgtgaa ggaatcagca 1100

 tgggagatca tctctgggtg gcccgtttca tcttgcatcg tgtgtgtgaa 1150

 gactttggag tgatagcaac ctttgatcct aagcccattc ctgggaactg 1200

 gaatggtgca ggctgccata ccaacttcag caccaaggcc atgcgggagg 1250

 agaatggtct gaagtacatc gaggaggcca ttgagaaact aagcaagcgg 1300

 caccagtacc acatccgtgc ctatgatccc aagggaggcc tggacaatgc 1350

 ccgacgtcta actggattcc atgaaacctc caacatcaac gacttttctg 1400

 ctggtgtagc caatcgtagc gccagcatac gcattccccg gactgttggc 1450

 caggagaaga agggttactt tgaagatcgt cgcccctctg ccaactgcga 1500

 ccccttttcg gtgacagaag ccctcatccg cacgtgtctt ctcaatgaaa 1550

 ccggcgatga gcccttccag tacaaaaatt aagtggacta gacctccagc 1600

 tgttgagccc ctcctagttc ttcatcccac tccaactctt ccccctctcc 1650

 cagttgtccc gattgtaact caaagggtgg aatatcaagg tcgttttttt 1700

 cattccatgt gcccagttaa tcttgctttc tttgtttggc tgggatagag 1750

 gggtcaagtt attaatttct tcacacctac cctccttttt ttccctatca 1800

 ctgaagcttt ttagtgcatt agtggggagg agggtgggga gacataacca 1850

 ctgcttccat ttaatggggt gcacctgtcc aataggcgta gctatccgga 1900

 cagagcacgt ttgcagaagg gggactcttc ttccaggtag ctgaaagggg 1950

 aagacctgac gtactctggt taggttagga cttgccctcg tggtggaaac 2000

 ttttcttaaa aagttataac caacttttct attaaaagtg ggaattagga 2050

 gagaaggtag gggttgggaa tcagagagaa tggctttggt ctcttgcttg 2100

 tgggactagc ctggcttggg actaaatgcc ctgctctgaa cacgaagctt 2150

 agtataaact gatggatatc cctaccttga aagaagaaaa ggttcttact 2200

 gcttggtcct tgatttatca cacaaagcag aatagtattt ttatatttaa 2250

 atgtaaagac aaaaaactat atgtatggtt ttgtggatta tgtgtgtttt 2300

 gctaaaggaa aaaaccatcc aggtcacggg gcaccaaatt tgagacaaat 2350

 agtcggatta gaaataaagc atctcatttt gagtagagag caagggaagt 2400

 ggttcttaga tggtgatctg ggattaggcc ctcaagaccc ttttgggttt 2450

 ctgccctgcc caccctctgg agaaggtggg cactggatta gttaacagac 2500

 gacacgttac tagcagtcac ttgatctccg tggctttggt ttaaaagaca 2550

 cacttgtcca cataggttta gagataagag ttggctgttc aacttgagca 2600

 tgttactgac agagggggta ttggggttat tttctggtag gaatagcatg 2650

 tcactaaagc aggccttttg atattaaatt ttttaaaaag caaaattata 2700

 gaagtttaga ttttaatcaa atttgtaggg tttctaggta atttttacag 2750

 aattgcttgt ttgcttcaac tgtctcctac ctctgctctt ggaggagatg 2800

 gggacagggc tggagtcaaa acacttgtaa ttttgtatct tgatgtcttt 2850

 gttaagactg ctgaagaatt attttttttc ttttataata aggaataaac 2900

 cccaccttta ttccttcatt tcatctacca ttttctggtt cttgtgttgg 2950

 ctgtggcagg ccagctgtgg ttttcttttg ccatgacaac ttctaattgc 3000

 catgtacagt atgttcaaag tcaaataact cctcattgta aacaaactgt 3050

 gtaactgccc aaagcagcac ttataaatca gcctaacata aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 3137

<210> 2942
<211> 373
<212> PRT
<213> Homo sapien

<400> 2942
 Met Thr Thr Ser Ala Ser Ser His Leu Asn Lys Gly Ile Lys Gln
   1               5                  10                  15

 Val Tyr Met Ser Leu Pro Gln Gly Glu Lys Val Gln Ala Met Tyr
                  20                  25                  30

 Ile Trp Ile Asp Gly Thr Gly Glu Gly Leu Arg Cys Lys Thr Arg
                  35                  40                  45

 Thr Leu Asp Ser Glu Pro Lys Cys Val Glu Glu Leu Pro Glu Trp
                  50                  55                  60

 Asn Phe Asp Gly Ser Ser Thr Leu Gln Ser Glu Gly Ser Asn Ser
                  65                  70                  75

 Asp Met Tyr Leu Val Pro Ala Ala Met Phe Arg Asp Pro Phe Arg
                  80                  85                  90

 Lys Asp Pro Asn Lys Leu Val Leu Cys Glu Val Phe Lys Tyr Asn
                  95                 100                 105

 Arg Arg Pro Ala Glu Thr Asn Leu Arg His Thr Cys Lys Arg Ile
                 110                 115                 120

 Met Asp Met Val Ser Asn Gln His Pro Trp Phe Gly Met Glu Gln
                 125                 130                 135

 Glu Tyr Thr Leu Met Gly Thr Asp Gly His Pro Phe Gly Trp Pro
                 140                 145                 150

 Ser Asn Gly Phe Pro Gly Pro Gln Gly Pro Tyr Tyr Cys Gly Val
                 155                 160                 165

 Gly Ala Asp Arg Ala Tyr Gly Arg Asp Ile Val Glu Ala His Tyr
                 170                 175                 180

 Arg Ala Cys Leu Tyr Ala Gly Val Lys Ile Ala Gly Thr Asn Ala
                 185                 190                 195

 Glu Val Met Pro Ala Gln Trp Glu Phe Gln Ile Gly Pro Cys Glu
                 200                 205                 210

 Gly Ile Ser Met Gly Asp His Leu Trp Val Ala Arg Phe Ile Leu
                 215                 220                 225

 His Arg Val Cys Glu Asp Phe Gly Val Ile Ala Thr Phe Asp Pro
                 230                 235                 240

 Lys Pro Ile Pro Gly Asn Trp Asn Gly Ala Gly Cys His Thr Asn
                 245                 250                 255

 Phe Ser Thr Lys Ala Met Arg Glu Glu Asn Gly Leu Lys Tyr Ile
                 260                 265                 270

 Glu Glu Ala Ile Glu Lys Leu Ser Lys Arg His Gln Tyr His Ile
                 275                 280                 285

 Arg Ala Tyr Asp Pro Lys Gly Gly Leu Asp Asn Ala Arg Arg Leu
                 290                 295                 300

 Thr Gly Phe His Glu Thr Ser Asn Ile Asn Asp Phe Ser Ala Gly
                 305                 310                 315

 Val Ala Asn Arg Ser Ala Ser Ile Arg Ile Pro Arg Thr Val Gly
                 320                 325                 330

 Gln Glu Lys Lys Gly Tyr Phe Glu Asp Arg Arg Pro Ser Ala Asn
                 335                 340                 345

 Cys Asp Pro Phe Ser Val Thr Glu Ala Leu Ile Arg Thr Cys Leu
                 350                 355                 360

 Leu Asn Glu Thr Gly Asp Glu Pro Phe Gln Tyr Lys Asn
                 365                 370

<210> 2943
<211> 1666
<212> DNA
<213> Homo sapien

<400> 2943
 acgcgtccga aagcggccat gttttacata tttcttgatt ttgtttgttt 50

 tctcgtgagc ttaggccgct ggttttggtg atttttgtct gattgcaatg 100

 tctggacgtg gtaagcaagg aggcaaagct cgcgccaaag cgaaatcccg 150

 ctcttctcgc gctggtctcc agttcccggt gggccgagtg caccgcctgc 200

 tccgtaaagg caactacgca gagcgggttg gggcaggcgc gccggtgtac 250

 ctggcggcgg tgttagagta cctgaccgcc gagatcctgg agctggccgg 300

 caacgcggct cgcgacaaca agaagactcg catcatcccg cgccacttgc 350

 agctggccat ccgcaacgac gaggagctca acaaactgct aggccgggtg 400

 accattgctc agggcggcgt ccttcctaac atccaggccg tgcttctgcc 450

 taagaagacc gagagtcacc acaaggccaa gggcaagtga tttgacaggt 500

 atctgagctc ccggaaacgc tatcaaaccc aaaggctctt ttcagagccc 550

 ccctaccgtt tcaaaggaag agctaacctc actgcttgta ggtagaagga 600

 aaaaagcact aaggttgcaa aagcttctca tttcagagag atgccaggat 650

 cctaagtgcc tgccaaactt accaattcta aggaataagt ggatggatgg 700

 cattactgat tcctacatta ctgattgatt ctgcatccac aaattgtttt 750

 attaaaaaca ttctacatca tgtgtgggga gataaggagg ataaaatgaa 800

 gagaaagaat attattgagg ggaagttctt ctgaatacaa aatgtgttta 850

 attttttaaa taagtattac attcacaggg ttcaaactat ttgaagtaaa 900

 gagattatat aaagaatcca tccctcaact tacccaggtg gtcacttttc 950

 tttttcttgt gtatctgccc agtattcatt cctgctgata tcagtcaata 1000

 atgaatgata cgtgttttct tcactttttt cattcttgtc aggtagcaga 1050

 ctgtgtagac ttttctgcac ttgccctttt cataacaatc tatcttggag 1100

 aactttccct atgagaacat acagagcttc ctgtacacag ttgcatgtac 1150

 tgcattatgc aaatgcatta tattttatgt aacctgtcca ctgttggtag 1200

 gcacttgagt tgttttagtc ttttgctatc aaacagttct gggatgatta 1250

 accctgattt actgcaaaat tgaaattgct ctgctattct gctggaatgg 1300

 tggtaagtga actgaaaatt ccagtcactc ttgggctaga ctcaacgttc 1350

 ttaaaaacta tgtggccatc accaaattag ttattttgaa ccttaatttc 1400

 ttcacctcta aaatggaggt aatacttacc ttaagtggct atgagaatga 1450

 agatcatgtg tatgaattgt tggtgctcta aagaacagca caaataaaat 1500

 tattttcaaa tttaatttta attgaactat gtgtaatttc ttaattttga 1550

 aataatttta tttgtaatgt gcataatctt atttaatgta taatgtatac 1600

 attgtaatag aaacagattt cccaaattcc agcctggcat gaggtaataa 1650

 aaggtaatgc aaaaaa 1666

<210> 2944
<211> 130
<212> PRT
<213> Homo sapien

<400> 2944
 Met Ser Gly Arg Gly Lys Gln Gly Gly Lys Ala Arg Ala Lys Ala
   1               5                  10                  15

 Lys Ser Arg Ser Ser Arg Ala Gly Leu Gln Phe Pro Val Gly Arg
                  20                  25                  30

 Val His Arg Leu Leu Arg Lys Gly Asn Tyr Ala Glu Arg Val Gly
                  35                  40                  45

 Ala Gly Ala Pro Val Tyr Leu Ala Ala Val Leu Glu Tyr Leu Thr
                  50                  55                  60

 Ala Glu Ile Leu Glu Leu Ala Gly Asn Ala Ala Arg Asp Asn Lys
                  65                  70                  75

 Lys Thr Arg Ile Ile Pro Arg His Leu Gln Leu Ala Ile Arg Asn
                  80                  85                  90

 Asp Glu Glu Leu Asn Lys Leu Leu Gly Arg Val Thr Ile Ala Gln
                  95                 100                 105

 Gly Gly Val Leu Pro Asn Ile Gln Ala Val Leu Leu Pro Lys Lys
                 110                 115                 120

 Thr Glu Ser His His Lys Ala Lys Gly Lys
                 125                 130

<210> 2945
<211> 1336
<212> DNA
<213> Homo sapien

<400> 2945
 tgcattgcta cctgcccttc tcaaagccca catgttgtat tttatgcaaa 50

 tctacagatt atctatcatt atctaaatgc aggcatctga aaaccagcag 100

 taatcctgcc tctgaagttt atcaggaaag gagcttaaaa gagaaccaaa 150

 ttcagcctgt gttggaactc tcagtcccag aggggtgtgg tttgtagctc 200

 tccggcctgc tgttggactt aggctgtgac ccacagaagg acgccagaaa 250

 gtactcaaga cattcacggt gccccggtca gcactcgcca tgacgaagac 300

 ttctacatgc atataccact tccttgttct gagctggtat actttcctca 350

 attattacat ctcacaggaa ggaaaagacg aggtgaaacc caaaatcttg 400

 gcaaatggtg caaggtggaa atatatgacg ctgcttaatc tgctcttgca 450

 gaccattttc tacggggtca cctgcctgga tgatgtgctg aaaagaacca 500

 aagggggaaa agacattaag ttcctaactg ccttcagaga cctgcttttc 550

 accactctgg cttttcctgt atccacgttt gtatttttgg cattctggat 600

 cctctttctc tacaatcgag atctcattta ccccaaggtc ctagatactg 650

 tcatccccgt gtggctgaat catgcaatgc acactttcat attccccatc 700

 acattggctg aagtcgtcct caggcctcac tcctatccat caaagaagac 750

 aggactcacc ttgctggctg ctgccagcat tgcttacatc agccgcatcc 800

 tatggctcta ctttgagacg ggtacctggg tgtatcctgt gtttgccaaa 850

 ctcagcctct tgggtctagc agctttcttc tctctcagct acgtcttcat 900

 cgccagcatc tacctacttg gagagaagct caaccactgg aaatgggttt 950

 ctgttcagat cttgcaaaga tggaggctag aatctgttgg aatctgcttc 1000

 cagtggcccg attggaagtc accagccaag caccaactgg tcaagaatat 1050

 caggtgaaat atcagggcta taaaaatatt tctagccctt gctactatct 1100

 gacagcagtt aaaggaataa aacaagtcgg ggtgaatcta acttcctatc 1150

 tgccaactag gatactttct actgggaaaa atgcttctca atcaagaaaa 1200

 tatttataat aaacataatt ttccaattac aacttaaaat ccattttgtg 1250

 aatttggttt gggtaagata tatgatctat tattaagtca acagtttcct 1300

 tatttccagc tatgcgttat agaaacatgg tcagaa 1336

<210> 2946
<211> 255
<212> PRT
<213> Homo sapien

<400> 2946
 Met Thr Lys Thr Ser Thr Cys Ile Tyr His Phe Leu Val Leu Ser
   1               5                  10                  15

 Trp Tyr Thr Phe Leu Asn Tyr Tyr Ile Ser Gln Glu Gly Lys Asp
                  20                  25                  30

 Glu Val Lys Pro Lys Ile Leu Ala Asn Gly Ala Arg Trp Lys Tyr
                  35                  40                  45

 Met Thr Leu Leu Asn Leu Leu Leu Gln Thr Ile Phe Tyr Gly Val
                  50                  55                  60

 Thr Cys Leu Asp Asp Val Leu Lys Arg Thr Lys Gly Gly Lys Asp
                  65                  70                  75

 Ile Lys Phe Leu Thr Ala Phe Arg Asp Leu Leu Phe Thr Thr Leu
                  80                  85                  90

 Ala Phe Pro Val Ser Thr Phe Val Phe Leu Ala Phe Trp Ile Leu
                  95                 100                 105

 Phe Leu Tyr Asn Arg Asp Leu Ile Tyr Pro Lys Val Leu Asp Thr
                 110                 115                 120

 Val Ile Pro Val Trp Leu Asn His Ala Met His Thr Phe Ile Phe
                 125                 130                 135

 Pro Ile Thr Leu Ala Glu Val Val Leu Arg Pro His Ser Tyr Pro
                 140                 145                 150

 Ser Lys Lys Thr Gly Leu Thr Leu Leu Ala Ala Ala Ser Ile Ala
                 155                 160                 165

 Tyr Ile Ser Arg Ile Leu Trp Leu Tyr Phe Glu Thr Gly Thr Trp
                 170                 175                 180

 Val Tyr Pro Val Phe Ala Lys Leu Ser Leu Leu Gly Leu Ala Ala
                 185                 190                 195

 Phe Phe Ser Leu Ser Tyr Val Phe Ile Ala Ser Ile Tyr Leu Leu
                 200                 205                 210

 Gly Glu Lys Leu Asn His Trp Lys Trp Val Ser Val Gln Ile Leu
                 215                 220                 225

 Gln Arg Trp Arg Leu Glu Ser Val Gly Ile Cys Phe Gln Trp Pro
                 230                 235                 240

 Asp Trp Lys Ser Pro Ala Lys His Gln Leu Val Lys Asn Ile Arg
                 245                 250                 255

<210> 2947
<211> 739
<212> DNA
<213> Homo sapien

<400> 2947
 ctccagaaaa agtactttaa gttacctaca ggtgatccta gtcaggcaaa 50

 tgaaaacagt agcctaaagt gtcagtttca accagaaaat aacagctctg 100

 atttctcatg gctcatactc gtctgaaacg actcaggtag aggctgagga 150

 aggccgtgtt gtttgtctac ctgggactac acctactgaa agaagttctc 200

 aagttctgat tgagttctaa aattttttga agattgaaat tcttcatatg 250

 taaaaagaga agagaaagac attcttgatt ttggtgacta gagttgtaga 300

 tgctggaagc tttgccacta acattgatga accagatgca tgtcaccagc 350

 ccatcacggt gattcttaat gccggcacca tgggcccggc actgccacgt 400

 tttccaagga acctgccgga gctcctgcgg aagctgctcc tcaggcgatg 450

 gagtcccttc gctggtaggc ccttcttcag tcaccacagg atgcctgcca 500

 ttcatgaaca agaaggagag gacgggcttt gaataaaaaa caggatccag 550

 gaaatatttg tgaggccatt tggacttcag tgtgaaatgg tgttaaaaga 600

 tgaagtcatt tattcaagaa gtaaacctct gccacctgga ctgtgcgcag 650

 acatttcatt gatttggttt aataaacatt ttctggcttt gggaggtgtc 700

 tctcttggta gaacacagtg tcaaagatgg acaagatgg 739

<210> 2948
<211> 50
<212> PRT
<213> Homo sapien

<400> 2948
 Met Val Leu Lys Asp Glu Val Ile Tyr Ser Arg Ser Lys Pro Leu
   1               5                  10                  15

 Pro Pro Gly Leu Cys Ala Asp Ile Ser Leu Ile Trp Phe Asn Lys
                  20                  25                  30

 His Phe Leu Ala Leu Gly Gly Val Ser Leu Gly Arg Thr Gln Cys
                  35                  40                  45

 Gln Arg Trp Thr Arg
                  50

<210> 2949
<211> 986
<212> DNA
<213> Homo sapien

<400> 2949
 gcaggcgcag acgcgcgggc gggaagatgg cggctgggtt caaaaccgtg 50

 gaacctctgg agtattacag gagatttctg aaagagaact gccgtcctga 100

 tggaagagaa cttggtgaat tcagaaccac aactgtcaac atcggttcaa 150

 ttagtaccgc agatggttct gctttagtga agttgggaaa tactacagta 200

 atctgtggag ttaaagcaga atttgcagca ccatcaacag atgcccctga 250

 taaaggatac gttgttccta atgtggatct accacccctg tgttcatcga 300

 gattccggtc tggacctcct ggagaagagg cccaagtggc tagccaattc 350

 attgcagatg tcattgaaaa ttcacagata attcagaaag aggacttatg 400

 catttctcca ggaaagcttg tctgggttct atactgtgat ctcatttgcc 450

 tcgactacga tggaaacatt ttggatgcct gcacatttgc tttgctagcg 500

 gctttaaaaa atgtacagtt gcctgaagtt actataaatg aagaaactgc 550

 tttagcagaa gttaatttaa agaagaaaag ttatttgaat attagaactc 600

 atccagttgc aacttccttt gctgtgtttg atgacacttt gcttatagtt 650

 gaccctactg gagaggagga acatctggca acaggaacct taacaatagt 700

 aatggatgag gaaggcaaac tctgttgtct tcacaaacca ggtggaagtg 750

 ggctaactgg agctaaactt caggactgta tgagccgagc agttacaaga 800

 cacaaagaag ttaaaaaact gatggatgaa gtaattaaga gtatgaaacc 850

 caaataaaca gccaccacat tttcaaaaca gatttgtaaa aattgtattt 900

 gttaacactg tgcacaaacg ttttatacta aataaatatc aaactacatt 950

 cttccgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 986

<210> 2950
<211> 276
<212> PRT
<213> Homo sapien

<400> 2950
 Met Ala Ala Gly Phe Lys Thr Val Glu Pro Leu Glu Tyr Tyr Arg
   1               5                  10                  15

 Arg Phe Leu Lys Glu Asn Cys Arg Pro Asp Gly Arg Glu Leu Gly
                  20                  25                  30

 Glu Phe Arg Thr Thr Thr Val Asn Ile Gly Ser Ile Ser Thr Ala
                  35                  40                  45

 Asp Gly Ser Ala Leu Val Lys Leu Gly Asn Thr Thr Val Ile Cys
                  50                  55                  60

 Gly Val Lys Ala Glu Phe Ala Ala Pro Ser Thr Asp Ala Pro Asp
                  65                  70                  75

 Lys Gly Tyr Val Val Pro Asn Val Asp Leu Pro Pro Leu Cys Ser
                  80                  85                  90

 Ser Arg Phe Arg Ser Gly Pro Pro Gly Glu Glu Ala Gln Val Ala
                  95                 100                 105

 Ser Gln Phe Ile Ala Asp Val Ile Glu Asn Ser Gln Ile Ile Gln
                 110                 115                 120

 Lys Glu Asp Leu Cys Ile Ser Pro Gly Lys Leu Val Trp Val Leu
                 125                 130                 135

 Tyr Cys Asp Leu Ile Cys Leu Asp Tyr Asp Gly Asn Ile Leu Asp
                 140                 145                 150

 Ala Cys Thr Phe Ala Leu Leu Ala Ala Leu Lys Asn Val Gln Leu
                 155                 160                 165

 Pro Glu Val Thr Ile Asn Glu Glu Thr Ala Leu Ala Glu Val Asn
                 170                 175                 180

 Leu Lys Lys Lys Ser Tyr Leu Asn Ile Arg Thr His Pro Val Ala
                 185                 190                 195

 Thr Ser Phe Ala Val Phe Asp Asp Thr Leu Leu Ile Val Asp Pro
                 200                 205                 210

 Thr Gly Glu Glu Glu His Leu Ala Thr Gly Thr Leu Thr Ile Val
                 215                 220                 225

 Met Asp Glu Glu Gly Lys Leu Cys Cys Leu His Lys Pro Gly Gly
                 230                 235                 240

 Ser Gly Leu Thr Gly Ala Lys Leu Gln Asp Cys Met Ser Arg Ala
                 245                 250                 255

 Val Thr Arg His Lys Glu Val Lys Lys Leu Met Asp Glu Val Ile
                 260                 265                 270

 Lys Ser Met Lys Pro Lys
                 275

<210> 2951
<211> 2244
<212> DNA
<213> Homo sapien

<400> 2951
 ctgcagacga ggcagggaga ggcgggactt cgcgggcgag acgtcatcgg 50

 ggcgccggac gccggggcgc ctgggagttt gaagcaaaca ggcagcgcgc 100

 gacaatggcg gtcgctcgtg cagctttggg gccattggtg acgggtctgt 150

 acgacgtgca ggctttcaag tttggggact tcgtgctgaa gagcgggctt 200

 tcctccccca tctacatcga tctgcggggc atcgtgtctc gaccgcgtct 250

 tctgagtcag gttgcagata ttttattcca aactgcccaa aatgcaggca 300

 tcagttttga caccgtgtgt ggagtgcctt atacagcttt gccattggct 350

 acagttatct gttcaaccaa tcaaattcca atgcttatta gaaggaaaga 400

 aacaaaggat tatggaacta agcgtcttgt agaaggaact attaatccag 450

 gagaaacctg tttaatcatt gaagatgttg tcaccagtgg atctagtgtt 500

 ttggaaactg ttgaggttct tcagaaggag ggcttgaagg tcactgatgc 550

 catagtgctg ttggacagag agcagggagg caaggacaag ttgcaggcgc 600

 acgggatccg cctccactca gtgtgtacat tgtccaaaat gctggagatt 650

 ctcgagcagc agaaaaaagt tgatgctgag acagttggga gagtgaagag 700

 gtttattcag gagaatgtct ttgtggcagc gaatcataat ggttctcccc 750

 tttctataaa ggaagcaccc aaagaactca gcttcggtgc acgtgcagag 800

 ctgcccagga tccacccagt tgcatcgaag cttctcaggc ttatgcaaaa 850

 gaaggagacc aatctgtgtc tatctgctga tgtttcactg gccagagagc 900

 tgttgcagct agcagatgct ttaggaccta gtatctgcat gctgaagact 950

 catgtagata ttttgaatga ttttactctg gatgtgatga aggagttgat 1000

 aactctggca aaatgccatg agttcttgat atttgaagac cggaagtttg 1050

 cagatatagg aaacacagtg aaaaagcagt atgaaggagg tatctttaaa 1100

 atagcttcct gggcagatct agtaaatgct cacgtggtgc caggctcagg 1150

 agttgtgaaa ggcctgcaag aagtgggcct gcctttgcat cgggggtgcc 1200

 tccttattgc ggaaatgagc tccaccggct ccctggccac tggggactac 1250

 actagagcag cggttagaat ggctgaggag cactctgaat ttgttgttgg 1300

 ttttatttct ggctcccgag taagcatgaa accagaattt cttcacttga 1350

 ctccaggagt tcagttggaa gcaggaggag ataatcttgg ccaacagtac 1400

 aatagcccac aagaagttat tggcaaacga ggttccgata tcatcattgt 1450

 aggtcgtggc ataatctcag cagctgatcg tctggaagca gcagagatgt 1500

 acagaaaagc tgcttgggaa gcgtatttga gtagacttgg tgtttgagtg 1550

 cttcagatac atttttcaga tacaatgtga agacattgaa gatatgtggt 1600

 cctcctgaaa gtcactggct ggaaataatc caattattcc tgcttggatt 1650

 cttccacagg gcctgtgtaa gaatgggttc tggagttctc atggtcttta 1700

 ggaaatattg agtaatttgt aatcaccgca ttgatactat aataagttca 1750

 ttcttaagct tgcttttttt gagactggtg tttgttagac agccacagtc 1800

 ctgtctgggt tagggtcttc cacatttgag gatccttcct atctctccat 1850

 gggactagac tgctttgtta ttctatttat tttttaattt ttttcgagac 1900

 aggatctcac tctgttgccc aggatggagt gcagtggtga gatcacggct 1950

 cattgcagcc tcgacctccc aggtgatcct cccacctcag cttccagatt 2000

 agctggtgct ataggcatgc accaccacgt ccatctaaat ttctttatta 2050

 tttgtagaga tgaggtcttg ccatgttacc caggctggtc tcaactcctg 2100

 ggctcaagcg atcctcctgc ctcagtctct caaagtgctg ggattacagg 2150

 tgtgagccac tgtgcccagc ctaattgcag taagacaaaa attctagggc 2200

 accaagaggc taaagtcagc acagcttttc ttgtgtcctg tatt 2244

<210> 2952
<211> 480
<212> PRT
<213> Homo sapien

<400> 2952
 Met Ala Val Ala Arg Ala Ala Leu Gly Pro Leu Val Thr Gly Leu
   1               5                  10                  15

 Tyr Asp Val Gln Ala Phe Lys Phe Gly Asp Phe Val Leu Lys Ser
                  20                  25                  30

 Gly Leu Ser Ser Pro Ile Tyr Ile Asp Leu Arg Gly Ile Val Ser
                  35                  40                  45

 Arg Pro Arg Leu Leu Ser Gln Val Ala Asp Ile Leu Phe Gln Thr
                  50                  55                  60

 Ala Gln Asn Ala Gly Ile Ser Phe Asp Thr Val Cys Gly Val Pro
                  65                  70                  75

 Tyr Thr Ala Leu Pro Leu Ala Thr Val Ile Cys Ser Thr Asn Gln
                  80                  85                  90

 Ile Pro Met Leu Ile Arg Arg Lys Glu Thr Lys Asp Tyr Gly Thr
                  95                 100                 105

 Lys Arg Leu Val Glu Gly Thr Ile Asn Pro Gly Glu Thr Cys Leu
                 110                 115                 120

 Ile Ile Glu Asp Val Val Thr Ser Gly Ser Ser Val Leu Glu Thr
                 125                 130                 135

 Val Glu Val Leu Gln Lys Glu Gly Leu Lys Val Thr Asp Ala Ile
                 140                 145                 150

 Val Leu Leu Asp Arg Glu Gln Gly Gly Lys Asp Lys Leu Gln Ala
                 155                 160                 165

 His Gly Ile Arg Leu His Ser Val Cys Thr Leu Ser Lys Met Leu
                 170                 175                 180

 Glu Ile Leu Glu Gln Gln Lys Lys Val Asp Ala Glu Thr Val Gly
                 185                 190                 195

 Arg Val Lys Arg Phe Ile Gln Glu Asn Val Phe Val Ala Ala Asn
                 200                 205                 210

 His Asn Gly Ser Pro Leu Ser Ile Lys Glu Ala Pro Lys Glu Leu
                 215                 220                 225

 Ser Phe Gly Ala Arg Ala Glu Leu Pro Arg Ile His Pro Val Ala
                 230                 235                 240

 Ser Lys Leu Leu Arg Leu Met Gln Lys Lys Glu Thr Asn Leu Cys
                 245                 250                 255

 Leu Ser Ala Asp Val Ser Leu Ala Arg Glu Leu Leu Gln Leu Ala
                 260                 265                 270

 Asp Ala Leu Gly Pro Ser Ile Cys Met Leu Lys Thr His Val Asp
                 275                 280                 285

 Ile Leu Asn Asp Phe Thr Leu Asp Val Met Lys Glu Leu Ile Thr
                 290                 295                 300

 Leu Ala Lys Cys His Glu Phe Leu Ile Phe Glu Asp Arg Lys Phe
                 305                 310                 315

 Ala Asp Ile Gly Asn Thr Val Lys Lys Gln Tyr Glu Gly Gly Ile
                 320                 325                 330

 Phe Lys Ile Ala Ser Trp Ala Asp Leu Val Asn Ala His Val Val
                 335                 340                 345

 Pro Gly Ser Gly Val Val Lys Gly Leu Gln Glu Val Gly Leu Pro
                 350                 355                 360

 Leu His Arg Gly Cys Leu Leu Ile Ala Glu Met Ser Ser Thr Gly
                 365                 370                 375

 Ser Leu Ala Thr Gly Asp Tyr Thr Arg Ala Ala Val Arg Met Ala
                 380                 385                 390

 Glu Glu His Ser Glu Phe Val Val Gly Phe Ile Ser Gly Ser Arg
                 395                 400                 405

 Val Ser Met Lys Pro Glu Phe Leu His Leu Thr Pro Gly Val Gln
                 410                 415                 420

 Leu Glu Ala Gly Gly Asp Asn Leu Gly Gln Gln Tyr Asn Ser Pro
                 425                 430                 435

 Gln Glu Val Ile Gly Lys Arg Gly Ser Asp Ile Ile Ile Val Gly
                 440                 445                 450

 Arg Gly Ile Ile Ser Ala Ala Asp Arg Leu Glu Ala Ala Glu Met
                 455                 460                 465

 Tyr Arg Lys Ala Ala Trp Glu Ala Tyr Leu Ser Arg Leu Gly Val
                 470                 475                 480

<210> 2953
<211> 1645
<212> DNA
<213> Homo sapien

<400> 2953
 agtcaagatg gaggagtacg cgcgagagcc ttgcccatgg cgaattgtgg 50

 atgactgtgg tggggccttt acgatgggta ccattggtgg tggtatcttt 100

 caagcaatca aaggttttcg caattctcca gtgggagtaa accacagact 150

 acgagggagt ttgacagcta ttaaaaccag ggctccacag ttaggaggta 200

 gctttgcagt ttggggaggg ctgttttcca tgattgactg tagtatggtt 250

 caagtcagag gaaaggaaga tccctggaac tccatcacaa gtggtgcctt 300

 aacgggagcc atactggcag caagaaatgg accagtggcc atggttgggt 350

 cagccgcaat gggtggcatt ctcctagctt taattgaagg agctggtatc 400

 ttgttgacaa gatttgcctc tgcacagttt cccaatggtc ctcagtttgc 450

 agaagacccc tcccagttgc cttcaactca gttaccttcc tcaccttttg 500

 gagactatcg acaatatcag taggacttct ttcctaggat ttctttaaca 550

 gaacgagttg tggttcgaga aggatttcag aagatcaagt tacagtctgt 600

 ttttaaaacc ataggtggga cagctatggc caataggcta taaagagaca 650

 tttagcactt ttttctattt aaaggaacaa gcggggaagg gtgctaaaag 700

 ataatacgtt tatttattca cacttgaatt gcatttgtga tcaaaataaa 750

 tgtttaaatc gctaaaggaa aatacagtaa gtgcttgaaa gatgaaggac 800

 caaaaggcca aaaaacagtg aaatatgatc atcatctctt gcggacttct 850

 ctgcctggtt ttgtgtgttc tgttattcaa acaataaaaa gctggtggaa 900

 cttactcttt cttttaagat aagttgtaga cttcgatgtt tcatgctcat 950

 gtacttcaaa taatgcatgt tttatagtta gtccctcatc acttgaagtg 1000

 acttctgaga attatgcaga gtcaacatgg atcatttcac agtgagatgc 1050

 tttatggatt gaaggatatg gtaaaatgtt tatagtttac tttgaaagta 1100

 aaatatacta tgtcttggtt ttgaggatat tggatacaaa actctcttcc 1150

 tttagggcta ctgagtcttg attcctgatc atcagaaatt tcaccagaaa 1200

 caacttgctt ccaatatacc caattctata tgaagaattc atggagagtg 1250

 tactggcact ggaagagttt agtgtttctt gtatgcttga aaataaagta 1300

 tgtactgttt tgaatgtgtt ccaagtcctc tgcataaacg atgtattttg 1350

 gggtctggtt gggcctggaa aatggatgag cacttcagaa caggtcattt 1400

 tcctgatatt ggaagtgaca tgtggcccta taggaggcat gatgttagtt 1450

 aattacacat ttgcctacat ctgtgggaaa tggagaacaa agccatgtgg 1500

 gtactgtaaa cacacgttta tcttttggcc caatgccata catatggtag 1550

 gcatttaatt actgattgtg tttggataat ttgggaattt tcgactgtgg 1600

 taaaatatac ataaaataat acttattaaa aaaaaaaaaa aaaaa 1645

<210> 2954
<211> 171
<212> PRT
<213> Homo sapien

<400> 2954
 Met Glu Glu Tyr Ala Arg Glu Pro Cys Pro Trp Arg Ile Val Asp
   1               5                  10                  15

 Asp Cys Gly Gly Ala Phe Thr Met Gly Thr Ile Gly Gly Gly Ile
                  20                  25                  30

 Phe Gln Ala Ile Lys Gly Phe Arg Asn Ser Pro Val Gly Val Asn
                  35                  40                  45

 His Arg Leu Arg Gly Ser Leu Thr Ala Ile Lys Thr Arg Ala Pro
                  50                  55                  60

 Gln Leu Gly Gly Ser Phe Ala Val Trp Gly Gly Leu Phe Ser Met
                  65                  70                  75

 Ile Asp Cys Ser Met Val Gln Val Arg Gly Lys Glu Asp Pro Trp
                  80                  85                  90

 Asn Ser Ile Thr Ser Gly Ala Leu Thr Gly Ala Ile Leu Ala Ala
                  95                 100                 105

 Arg Asn Gly Pro Val Ala Met Val Gly Ser Ala Ala Met Gly Gly
                 110                 115                 120

 Ile Leu Leu Ala Leu Ile Glu Gly Ala Gly Ile Leu Leu Thr Arg
                 125                 130                 135

 Phe Ala Ser Ala Gln Phe Pro Asn Gly Pro Gln Phe Ala Glu Asp
                 140                 145                 150

 Pro Ser Gln Leu Pro Ser Thr Gln Leu Pro Ser Ser Pro Phe Gly
                 155                 160                 165

 Asp Tyr Arg Gln Tyr Gln
                 170

<210> 2955
<211> 2499
<212> DNA
<213> Homo sapien

<400> 2955
 agcggggtcc caactggcga ggctgctggg gttgcagcgg gacagttggg 50

 gcggccccgc aggcccaggt gaacaaaaat tgtttgctgg cccccaggat 100

 actaactaga cctttggcct gactcacagg acactaaggc tccttttctg 150

 aagaagcctt ttaccagtct catttagggg atgggaacaa catgtcttca 200

 cctagggact ttagagcaga gcctgtaaac gattatgagg gaaatgactc 250

 tgaagcagaa gacttgaatt tcagggagac tttgccttca tcaagtcagg 300

 aaaacacacc tagatcaaag gtttttgaaa ataaagttaa ttcagagaag 350

 gtaaaacttt ctcttcggaa tttcccacat aatgattatg aggatgtttt 400

 tgaagagcct tcagaaagtg gcagtgatcc cagcatgtgg acagccagag 450

 gccccttcag aagagacagg tggagcagtg aggatgagga ggctgcaggg 500

 ccatcacagg ctctctcccc tctactttct ggtacgcgca aaattgtttc 550

 tgaaggagaa ctagatcagt tggctcagat tcggccatta atattcaatt 600

 ttcatgagca gacagccatc aaggattgtt tgaaaatcct tgaagaaaaa 650

 aacagcagcg tatgatatca tgcaggaatt tatggcttta gaacttaaga 700

 atctgcctgg tgagttcaac tctgggaatc aaccaagcaa cagagaaaaa 750

 aacagatacc gagatattct tccatttcaa catcatggat atagtggccc 800

 aaatgagaga acaacgttct ggcatggttc aaacgaagga gcagtatcac 850

 ttttgttacg atattgtgct tgaagttctt cggaaacttc tgactttgga 900

 ttaagaaaga cttctgttgc ctctcacttg aaattaccaa gtgggtttgc 950

 acctcctcat aaagaacatg tttgcactgt gctgaagggc tttgctatgc 1000

 atacaatctg ctttcttggt ttatcagttt attttctttc taaaagctcc 1050

 ctgaagggca atatcatttg gcttggggtg atcagtgttt acttattgat 1100

 cttgctagac aatatcaaaa taacttccca cattttccag tgaaacagat 1150

 gttacataaa acgattgcag cttggctatt tggttgaagg gattacagag 1200

 cccaataaag gatttaaaat atattcatta agattttatt tggaaaggtg 1250

 gctggagaga gctgaggatt tccaggactt tgtaagttct tattctggga 1300

 gaacataagg ccaataatca tgacctcttc caggcatttt taagacagat 1350

 gtctattcat gttctttagc tagagcctgt actttttgct ggcatttgaa 1400

 taacccagtt taaaaagagt ccagttaggg tggactaact ttggacacaa 1450

 attggcttcc atttcctaca ttttcatact gctgccttcc tacagctgct 1500

 agaccaagac ctgttggtct gggaagcatt tcatggatag ggagagctcc 1550

 tctcggtgaa cagtccaaaa ctaaaataga tgtttatata gaaagcccaa 1600

 gaggagactt ttgccatgcc tgagttcttt cctatcccac cctaacactt 1650

 aacatattac ttagtctgct ttgttaaaag caagtattac ctttaacttg 1700

 cctcttactc tttgcccttt agctaactaa taaagtttga tataggcatt 1750

 attatataat tctgagtcat tcatggtatc tctcatgttt gatgtatttt 1800

 tcaaactaag atctatgata gttttttttc cagagttcca ttaaatcatt 1850

 tatttccttt actttctcac ctctgttgaa acatttagaa actggatttg 1900

 ggaacccaat tttggaaaac cagattcata gtcatgaaaa tggaaacttc 1950

 catattctgt ttttgaaaag atgtggccat tattacagta attttattat 2000

 aggactttgc ctcgtacaat taatagtgat attttggaca aggagttctg 2050

 gtgacaagct atacctaatt ataagctata aaacaataga tatgagtgtt 2100

 tgtacagttt aactcaatgg agatcagaat attctatgta ttgagaaaat 2150

 gtttaatatc aatctataaa tcttgaattt ctaagaggct tattttgttc 2200

 ttttggctga atgagtatat ttgaattggt tgaataatta ataattctca 2250

 ttgtaaaaat aattatatgc caaaaatata tttgatgtta aatcaaatag 2300

 atgattctgt ttacattgtt catatgaata ataatctgtg ttaatttcat 2350

 tttgataatt ggcctttaat atttgtatct ctaattttat tttctctctg 2400

 ttactgtaaa ataatagcta taatgtataa caattttctt cagaagaatt 2450

 ctatgctatt attaaaataa aatatttact gtgaaaaaaa aaaaaaaaa 2499

<210> 2956
<211> 157
<212> PRT
<213> Homo sapien

<400> 2956
 Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr
   1               5                  10                  15

 Glu Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr
                  20                  25                  30

 Leu Pro Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe
                  35                  40                  45

 Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn
                  50                  55                  60

 Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu
                  65                  70                  75

 Ser Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe Arg
                  80                  85                  90

 Arg Asp Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser
                  95                 100                 105

 Gln Ala Leu Ser Pro Leu Leu Ser Gly Thr Arg Lys Ile Val Ser
                 110                 115                 120

 Glu Gly Glu Leu Asp Gln Leu Ala Gln Ile Arg Pro Leu Ile Phe
                 125                 130                 135

 Asn Phe His Glu Gln Thr Ala Ile Lys Asp Cys Leu Lys Ile Leu
                 140                 145                 150

 Glu Glu Lys Asn Ser Ser Val
                 155

<210> 2957
<211> 4410
<212> DNA
<213> Homo sapien

<400> 2957
 gaggaggagc tggagggggc gcggcttcct ctcggtcgct ccctggcgcc 50

 gggcctcttt ctctgcctgg cccagggctg gcggccggcg ggggtcgcgg 100

 cggcggcagt gggggcgctg gcgggccgcg ggtggcgggg gccgggccgc 150

 ggctccgggt gttaggagac aagatggcgg cggctctcag aaggccggtc 200

 tcctcctctc cgccgtcctc cgccccgccg ctcgccgcct cctcctctcg 250

 ggtctcctcc tcctcgtttg ctgcctcctc ctcctcctgc agcagcacca 300

 gcgaccgccg aagcgccggc tcgctcaccc ggagctccgg aggtggatag 350

 acggggcagc tgcaggctcc ggcgaccgag gccgagctgg ggccggggcg 400

 gggacggcgg cggcggcggc ggcgacggcg gcggcgccgg gtggggatgg 450

 ggtcgcagac gctgcagatc ctccgacagg gggtgtgggc cgcgctcagc 500

 gggggctggt actacgaccc gcaccaggcc accttcgtga acgcgctgca 550

 cctctacctg tggctcttct gctgggccta cccttcaccc tctacatggc 600

 ccttccttct accatgatta tagtagcagt ttattgtcct gtgatagctg 650

 ctgttttcat tgttctgaag atggtcaact atcgactaca cagagcactt 700

 gatgctggag aagttgtaga taggactgca aatgagttca cggatcagcg 750

 aaccaaagct gaacaaggca actgttcaac caggagaaaa gacagcaatg 800

 gaccgagtga tcctggtgga gggattgaaa tgtctgagtt catccgagag 850

 gccacacccc cagttggttg cagttccaga aattcttatg ccggtctaga 900

 tccaagcaac cagattggat ctggttcctc gcgtcttgga acagcagcaa 950

 ctattaaagg agatacagac actgctaaga cttctgatga tatcagttta 1000

 agtctgggcc aaagttctag tctttgtaag gaaggaagtg aagaacaaga 1050

 tttggcagct gatcggaagc tctttcgtct tgtctccaat gactccttca 1100

 tctctattca gccttcctta tcctcttgtg gacaggactt gccaagggac 1150

 ttcagtgaca aagtgaacct gccaagtcat aaccaccacc accatgttga 1200

 tcagtctctg tccagcgcct gtgacacaga agtagcttct cttgtacctt 1250

 tacactcaca ctcttataga aaagaccacc ggccgcgagg tgtaccacgg 1300

 acttctagct ctgctgtggc ttttccagac acttcactga atgattttcc 1350

 cctttatcag caaagacgtg gattagatcc agttagtgag ttagaatctt 1400

 ccaagcctct ttctggatcc aaagaatcct tggtggaaaa ttctggttta 1450

 tctggggaat ttcagcttgc tggtgacttg aaaatcaata cttctcagcc 1500

 acccacaaaa agtgggaaga gcaaaccttt gaaagcagag aaaagcatgg 1550

 acagcttgag gagcctgagc acacggagta gtgggtcaac agaaagctac 1600

 tgcagtggaa cggaccggga cactaacagt actgtcagca gctataaaag 1650

 tgagcagacc agctcaactc acatagagag catcctgtca gagcatgagg 1700

 agtctcctaa agcaggaaca aaaagtggga ggaagaaaga gtgctgtgca 1750

 ggcccagagg agaagaatag ctgtgccagt gacaaaagga ctagcagtga 1800

 aaagattgct atggaagcga gtaccaacag tggggttcac gaggccaagg 1850

 accccacccc ctctgatgag atgcacaacc agagaggtct cagcacctct 1900

 gcatctgaag aagccaataa aaatccccat gcaaatgaat ttacttccca 1950

 aggggacaga ccacctggga acactgcaga aaacaaagaa gagaagagtg 2000

 ataagtcagc tgtttctgtg gattccaaag tgcgtaaaga tgttggtgga 2050

 aagcaaaagg aaggggatgt tcgacctaaa tcttctagcg taatccatcg 2100

 gacagcttct gcccacaagt caggcaggag acgcacagga aaaaaacggg 2150

 ctagcagttt tgattcaagc cggcataggg actatgtttg ctttcgaggt 2200

 gtttctggta ccaagccaca cagtgctata ttttgtcatg acgaagactc 2250

 tagtgatcag agtgacttga gtagagcatc aagtgttcag tctgctcacc 2300

 agttcagcag tgatagctct tctagcacca cttctcattc ctgtcagtct 2350

 cctgagggca gatacagtgc tctaaagacc aaacacactc ataaagaaag 2400

 gggcacagac tctgaacaca cacacaaagc tcatttggtt cctgaaggaa 2450

 ccagcaaaaa gcgtgcaaca cgacggactt ctagcacaaa tagtgccaag 2500

 actcgtgccc gagtgttgag cctggacagt ggcacagtag catgtttgaa 2550

 tgactcaaac aggttaatgg cacctgaaag tataaagccc ttaaccactt 2600

 caaaatcaga tcttgaggcc aaagagggag aggtgctaga tgagctatct 2650

 ttattaggac gggcttccca gttagagaca gtcactcgat ctaggaatag 2700

 cttgccaaac caggttgcat ttcctgaagg ggaagagcaa gatgcagtca 2750

 gtggagcagc acaagccagc gaggaggcag tgtcatttcg ccgtgaacgc 2800

 agcacattta ggcgccaggc agtacggcgc cggcacaatg cagggagtaa 2850

 ccctacccct cctacattgc tcatcggatc acccctaagc cttcaagatg 2900

 gtcagcaagg ccagcagtcc acagcccagg tcaaagtcca gtcccgcccc 2950

 ccttcccagg ctgcagtgct cagtgctagt gcctccttgc tggtaagttc 3000

 tcttctacgc tgtatgagac tggtggctgt gatatgtcac ttgtgaattt 3050

 tgaaccagca gcaagaagag catccaatat ctgtgacaca gattctcatg 3100

 tatccagttc tacctcagtt cgattttatc cacatgatgt ggtaggtttt 3150

 tctttatttt tacaacatga taaattttca gattaaatct gaaatatgta 3200

 tttacataga tagctataaa agccataaaa attgatgaag ttacacaaaa 3250

 attttttgaa aactatggca aaatcacttt gctgccctcc agtggctctc 3300

 tttttctaag tcctttgata agaaacaaaa gtacaaggtt aagaaaccct 3350

 ggcatagagt attttaaaaa gtgttttgga aagtatttgt caatgcttag 3400

 agatagaaat ggctgtgtta tatataggaa gtaaattttc tcaactatac 3450

 ccagatatgt gtttgaaaag taaaaccctc cctacttttt ggctatagtg 3500

 tattcctgga aactgcatag gaaagcaaac atgggaagat gattgtttta 3550

 ttgttttcta cttttaaatg gtatgggaac cttgagatag caaaatgctg 3600

 cctagtacta tgccaaatac agtcaacttt tgatgctttc tgaggaaaag 3650

 aaaactggta aactgatgga tggatgagtt gaagttaaat atagtatagt 3700

 aatttgtata gcctcaggtg agcagcttgc caaaacaaac aaacaaacaa 3750

 acaaacaggg gtgagggatt tggaaatata gtaacaacaa tgataagaga 3800

 ctgtgggaag aaatgagagt tgctgccatc agatccaatg cagtggggct 3850

 cagatttaac actgataatg aggttcaaag cttaaggaga aaagactata 3900

 aatgtgagaa gagaagccac taacgattca cagtaagtgg ttttagtaga 3950

 ttcgctagct atacagttat aaaatcttaa ggttttttct taagcattcc 4000

 ctgagaaaaa tcttaagatt ttagacactt ttctagtcaa ttatttacaa 4050

 taggtttatt gattaattaa ctttgtttta gttcacttcc tattgtcacc 4100

 ttctatagtt tctggtaatc ataacatatt cataaagagt aggctgggcg 4150

 cagtggctcc tgcctgtaat cccagcactt tgagaggccg aggcgggtgg 4200

 atcacgaggt caagagttca agaccagcct ggccaagatg gtaaaatccc 4250

 gtctctacaa aaaatagaaa aagaattagc cgggcatggt ggcaggtgcc 4300

 tgtaatccca gctgcttggg aggctgaggc agagaattgc ttgaaccggg 4350

 gaggcagagg ttgcagtgag ccgagattgc accactgtac ttcagacaag 4400

 actctgtctc 4410

<210> 2958
<211> 2245
<212> DNA
<213> Homo sapien

<400> 2958
 gtacccccat cctttctctc gcccctccta cccgcagctc ctggcgctcg 50

 gcggggctaa ctgcagcgcg gagatctcgg ccgccaagct ccgcctcccg 100

 ccccgggctg tgccccgggg ctcgcctgag gccgaccacc cgcaccccac 150

 ctctagcggc tttgctcgag gcccaccttc ttcccacccc cggcaaactc 200

 cagtaggctc gccctcgctg actccccgcc cccgcgtcaa ctgcaagggg 250

 cccgcccata gccagttccg gggcggttgc tcacatcgac cggaactccc 300

 cgccccctcc cgcggcccct ggggccgtag gaggccgcag cgaggaggta 350

 gagggggcgg gggtcgcact agggtgtccc tagagaacga ggactctgaa 400

 ggcgggacat ttgggcgacc cccgggcggg gccagccatt aaacagtccc 450

 acttctgtgc cagacactga actgggctct tgacgggcat catctcttaa 500

 tcctcagaac atcccaggga gctccacagg atccccatat cctgggccat 550

 gagtgagttg aaagactgcc ccttgcagtt ccacgacttc aagtctgtgg 600

 atcacctgaa ggtctgtccc cgctacacgg cagtgctggc acgctctgag 650

 gatgatggca tcggcatcga ggagctggac accctgcagc tggagctgga 700

 gaccctgctg tcttctgcca gccggcgcct gcgtgtgctt gaggccgaaa 750

 cccagatcct caccgactgg caggataaga aaggtgacag acgattcctg 800

 aagctgggtc gagaccatga acttggagct ccccccaaac atgggaagcc 850

 caagaagcag aaactggaag ggaaggcagg acatgggccg ggccctggcc 900

 caggacggcc caaatccaaa aaccttcagc ccaagatcca ggaatatgaa 950

 ttcactgatg accctatcga cgtgccacgg atccccaaaa atgatgcccc 1000

 caacaggttc tgggcttcag tggagcccta ctgtgctgac atcaccagcg 1050

 aggaggtccg cacacttgag gagttactga agcccccaga agatgaggct 1100

 gagcattaca agatcccacc cctggggaag cactactccc agcgctgggc 1150

 ccaggaggac ctgctggagg agcagaagga tggggcccgg gcagcggctg 1200

 tggctgacaa gaagaaaggc ctcatggggc cactgaccga actggacact 1250

 aaagatgtgg atgccctgct gaagaagtct gaggcccagc atgaacagcc 1300

 ggaagatgga tgcccctttg gtgccctgac gcagcgcctc ctgcaggccc 1350

 tggtggagga aaatattatt tcccctatgg aggattctcc tattcctgac 1400

 atgtctggga aagaatcagg ggctgacggg gcaagcacct cccctcgcaa 1450

 tcagaacaag cccttcagtg tgccgcatac taagtccctg gagagccgca 1500

 tcaaggagga gctaattgcc cagggccttt tggagtctga ggaccgcccc 1550

 gcagaggact ccgaggatga ggtccttgct gagcttcgca aacggcaggc 1600

 tgagctgaag gcacttagtg cccacaaccg caccaagaag cacgacctgc 1650

 tgaggctggc aaaggaggag gtgagccggc aggagctgag gcagcgggtg 1700

 cgcatggctg acaacgaggt catggacgcc tttcgcaaga tcatggctgc 1750

 ccggcagaag aagcggactc ccaccaagaa agaaaaggac caggcctgga 1800

 agactctgaa ggagcgtgag agcatcctga agctgctgga tgggtagccc 1850

 tcacccctgc ctcaggctga ttatctggcc taggggaggg gaagggaggc 1900

 ccacttcctt ctttgggcac aggaaacatt ggcctgtggc tgtccctcaa 1950

 atggcggcag tctctagagg gccgtggccc ttcccctgag gtcttttggc 2000

 ctagctctgt acaaccagga cacaggaagc cctgctgggc tagcctgagg 2050

 cctagtctct gcttggtccc cgagatgggg ttggagggga cttcgtttct 2100

 gggtcttcct cttcccctct ttaccatccc ccactcccta atcccctacc 2150

 cctgtctccc cttcaaggac ttctcccttg tggttttgta aagtgcaaac 2200

 ttaagaataa agtgactgct gtggtttttc aaaaaaaaaa aaaaa 2245

<210> 2959
<211> 432
<212> PRT
<213> Homo sapien

<400> 2959
 Met Ser Glu Leu Lys Asp Cys Pro Leu Gln Phe His Asp Phe Lys
   1               5                  10                  15

 Ser Val Asp His Leu Lys Val Cys Pro Arg Tyr Thr Ala Val Leu
                  20                  25                  30

 Ala Arg Ser Glu Asp Asp Gly Ile Gly Ile Glu Glu Leu Asp Thr
                  35                  40                  45

 Leu Gln Leu Glu Leu Glu Thr Leu Leu Ser Ser Ala Ser Arg Arg
                  50                  55                  60

 Leu Arg Val Leu Glu Ala Glu Thr Gln Ile Leu Thr Asp Trp Gln
                  65                  70                  75

 Asp Lys Lys Gly Asp Arg Arg Phe Leu Lys Leu Gly Arg Asp His
                  80                  85                  90

 Glu Leu Gly Ala Pro Pro Lys His Gly Lys Pro Lys Lys Gln Lys
                  95                 100                 105

 Leu Glu Gly Lys Ala Gly His Gly Pro Gly Pro Gly Pro Gly Arg
                 110                 115                 120

 Pro Lys Ser Lys Asn Leu Gln Pro Lys Ile Gln Glu Tyr Glu Phe
                 125                 130                 135

 Thr Asp Asp Pro Ile Asp Val Pro Arg Ile Pro Lys Asn Asp Ala
                 140                 145                 150

 Pro Asn Arg Phe Trp Ala Ser Val Glu Pro Tyr Cys Ala Asp Ile
                 155                 160                 165

 Thr Ser Glu Glu Val Arg Thr Leu Glu Glu Leu Leu Lys Pro Pro
                 170                 175                 180

 Glu Asp Glu Ala Glu His Tyr Lys Ile Pro Pro Leu Gly Lys His
                 185                 190                 195

 Tyr Ser Gln Arg Trp Ala Gln Glu Asp Leu Leu Glu Glu Gln Lys
                 200                 205                 210

 Asp Gly Ala Arg Ala Ala Ala Val Ala Asp Lys Lys Lys Gly Leu
                 215                 220                 225

 Met Gly Pro Leu Thr Glu Leu Asp Thr Lys Asp Val Asp Ala Leu
                 230                 235                 240

 Leu Lys Lys Ser Glu Ala Gln His Glu Gln Pro Glu Asp Gly Cys
                 245                 250                 255

 Pro Phe Gly Ala Leu Thr Gln Arg Leu Leu Gln Ala Leu Val Glu
                 260                 265                 270

 Glu Asn Ile Ile Ser Pro Met Glu Asp Ser Pro Ile Pro Asp Met
                 275                 280                 285

 Ser Gly Lys Glu Ser Gly Ala Asp Gly Ala Ser Thr Ser Pro Arg
                 290                 295                 300

 Asn Gln Asn Lys Pro Phe Ser Val Pro His Thr Lys Ser Leu Glu
                 305                 310                 315

 Ser Arg Ile Lys Glu Glu Leu Ile Ala Gln Gly Leu Leu Glu Ser
                 320                 325                 330

 Glu Asp Arg Pro Ala Glu Asp Ser Glu Asp Glu Val Leu Ala Glu
                 335                 340                 345

 Leu Arg Lys Arg Gln Ala Glu Leu Lys Ala Leu Ser Ala His Asn
                 350                 355                 360

 Arg Thr Lys Lys His Asp Leu Leu Arg Leu Ala Lys Glu Glu Val
                 365                 370                 375

 Ser Arg Gln Glu Leu Arg Gln Arg Val Arg Met Ala Asp Asn Glu
                 380                 385                 390

 Val Met Asp Ala Phe Arg Lys Ile Met Ala Ala Arg Gln Lys Lys
                 395                 400                 405

 Arg Thr Pro Thr Lys Lys Glu Lys Asp Gln Ala Trp Lys Thr Leu
                 410                 415                 420

 Lys Glu Arg Glu Ser Ile Leu Lys Leu Leu Asp Gly
                 425                 430

<210> 2960
<211> 4572
<212> DNA
<213> Homo sapien

<400> 2960
 ggcggcgcta gcttcggagt ctcccgcgcg cacctcagcc gcctcctagc 50

 ggcgcggcgc tcgctcctac gcctaaaatg accaatgtgt gatttcagtg 100

 gaataaatgg cgtccaaagt cacagatgct atagtctggt atcaaaagaa 150

 gattggagca tatgatcaac aaatatggga aaaatctgtt gaacagagag 200

 aaatcaaggg gctaaggaat aaaccaaaga aaacagcaca tgtgaaacca 250

 gacctcatag atgttgatct tgtaagaggg tctgcatttg caaaggcaaa 300

 gcctgaaagt ccttggactt ctctgaccag aaagggaatt gttcgagttg 350

 tatttttccc ctttttcttc cggtggtggt tacaagtaac atcaaaggtc 400

 atctttttct ggcttcttgt cctttatctt cttcaagttg ctgcaatagt 450

 attattctgc tccacttcta gcccacacag catacctctg acagaggtga 500

 ttgggccgat atggctgatg ctgctcctgg gaactgtgca ttgccagatt 550

 gtttccacaa gaacacccaa acctcctcta agtacagggg gtaaaagaag 600

 aaggaaatta agaaaagcag cccatttgga agtacatagg gaaggagatg 650

 gttctagtac cacagataac acacaagagg gagcagttca gaaccacggt 700

 acaagcacct ctcacagcgt tggcactgtc ttcagagatc tctggcatgc 750

 tgctttcttt ttatcaggat caaagaaagc aaagaattca attgataaat 800

 caactgaaac tgacaatggc tatgtatccc ttgatgggaa gaagactgtt 850

 aaaagcggtg aagatggaat acaaaaccat gaacctcagt gtgaaactat 900

 tcgaccagaa gagacagcct ggaacacagg aacactgagg aatggtccta 950

 gcaaagatac ccaaaggaca ataacaaatg tctctgatga agtctccagt 1000

 gaggaaggtc ctgaaacagg atactcatta cgtcgtcatg tggacaggac 1050

 ttctgaaggt gttcttcgga atagaaagtc acaccattat aagaaacatt 1100

 accctaatga ggacgcccct aaatcgggta ctagttgcag ctctcgctgt 1150

 tcaagttcca gacaggattc tgagagtgca aggccagaat ctgaaacaga 1200

 agatgtgtta tgggaagact tgttacattg tgcagaatgc cattcatctt 1250

 gtaccagtga gacagatgtg gaaaatcatc agattaatcc atgtgtgaaa 1300

 aaagaatata gagatgaccc ttttcatcag agtcatttgc cctggctcca 1350

 tagttcccac ccaggattag aaaaaataag tgctatagta tgggaaggta 1400

 atgattgtaa gaaagcagac atgtctgtac ttgaaatcag tggaatgata 1450

 atgaacagag tgaacagcca tataccagga ataggatacc agatttttgg 1500

 aaatgcagtc tctctcatac tgggtttaac tccatttgtt ttccgacttt 1550

 ctcaagctac agacttggaa caactcacag cacattctgc ttcagaactt 1600

 tatgtgattg catttggttc taatgaagat gtcatagttc tttctatggt 1650

 tataataagt tttgtggttc gcgtgtctct tgtgtggatt ttcttttttt 1700

 tgctctgtgt agcagaaaga acttataaac agcgattact ttttgcaaaa 1750

 ctctttggac atttaacatc tgcaaggagg gctcgaaaat ctgaggttcc 1800

 tcatttccgg ttgaagaaag tacagaatat aaaaatgtgg ctatctctcc 1850

 gttcctatct taagcgtcga ggtcctcagc gatcagttga tgtaatagtt 1900

 tcatctgctt tcttattgac tatctcagtt gtatttatct gttgtgccca 1950

 gataaacctc tacttgaaaa tggagaaaaa acctaacaaa aaggaggaac 2000

 tgacactagt gaataatgtt ttaaaactgg ctactaaact gctaaaggag 2050

 ttggacagtc cttttagatt atatgggctt acaatgaatc cgctgcttta 2100

 taacatcacc caggttgtta tcctgtcagc tgtttctggt gttatcagtg 2150

 acttgcttgg atttaattta aagctatgga agattaagtc atgacaattc 2200

 aaagaaaaga agatgtagcc tcttttccag aataagagta ctgactaagc 2250

 tgcctgaaag cttgtcactg attctttgct tcaggagtct cagctaggga 2300

 gttgaagtgt ttacatcaga ctgtcttgtg caattcttat atttatttta 2350

 ctggttcact tttttttaca tttattttag tctttatatt tttattttta 2400

 agcattgatg tacttagttg ttgaaagggt gatgaaactg atatccagat 2450

 acttgagatc ctggtaattg gtcataaata attggcaaaa taacaaattg 2500

 tgaaaataga agccattgct cagcaccgtt tctccatcaa tgccgtgaac 2550

 ttgccttact tgaggaaaaa ttctttaact ttggaatatt gcattgaact 2600

 cagctataca cataaaacat tttctttggt aaatcaagat ccagtcaggg 2650

 tttctcttga attattttgg aacaatgcca ggatccaaac tgattaagtt 2700

 acagtttaag cacccttcag tattaatata tacggtatta tataacaggt 2750

 caacaagtgc tctttgatga taaaacttgt aatagagcaa taattgtaaa 2800

 tggttaccat actgtaagat attttgataa aaattaacta gtaatacttg 2850

 tatttatttg aaacactggg ctgtttgcac agctccaact gtgcatgctc 2900

 aaaatgtgca ctttttaaaa ttgttacttt taatgcgtat ctttatatgg 2950

 gatctgttat agtatactag ggcatgatat ggtatccttt tgagtgaggt 3000

 atatactcat ctcacaagtg aagtgcctac tgatattact aaagtacatt 3050

 atgtttactc aagtaaataa ttttctcccc atggtacact ctagtgtagg 3100

 ctattcatac cacactgaaa tgaacaactg aagaataagg ctaagaacca 3150

 ataaaatatt tctctaattg ctagttgtaa aactgtatcc aaattttcag 3200

 aaaagacagc ttcagcttgc aaattctatc ctctaaactt atctggtgca 3250

 ttctccccac cccaccccca ttatataagg gctattttag atgcttttaa 3300

 cctccccaac aaataatttg ccaagtgtcc aatgagaact tatcatgttg 3350

 gtgtgttagg taaatcgggc aaatatgata gtgtcttaca ttgggccttg 3400

 attttaagtt gttatatttg tacaatcgag tattttagaa attacatgaa 3450

 acatgaaaca gtttttgcaa ttttttttaa actgggcatc tggtttctaa 3500

 aaatttattt gaaacaatct agaattttct tggtgcaaag tgtatcatgt 3550

 ggaatatcct catattttta ccatatttta agaactttaa gacgattaat 3600

 tgtaaataat ttatttgatt ggtgcagttc taatccctaa atcataatct 3650

 taaaatcagg aatgtgtgga gaacagagcc atgtcatatc actttgctct 3700

 taccattcct tttgatcagc ctcaattcag cctcattgtg tagtatgttt 3750

 tttctttcta tgaaaaacaa cagaaagcat ttcattttat ttgcctatgt 3800

 tcaaatatgt ttaataatga ccaaagtgca ttctgagttt tttcaaggaa 3850

 tgtaatactg gagctttaag aacatactta gtttctcatg tgaaaactta 3900

 ggctttgtct gatgtttttc cttcctctat tgtctaatgt tgaggttgtt 3950

 tttaggaatt atgttttata aactttttca atataaggta catgcctata 4000

 cagaacttaa cattttgcac agaatatatc aaatatattt tgagaaaaaa 4050

 agtacggcat gagttctgtt aggaataaaa gatgaaacta ttgtatctca 4100

 caaaaaatct tatttcagaa tggaaatatt tttgagaaaa gtagctgagt 4150

 atactggttt aagaaaatgc ttgttttaga ttgaggttaa cttagagttg 4200

 ggagttgatt tattaagtac agtatacctc tcaacagttt ataaataata 4250

 tgttgaatta tgtcagtgtg ggcagcagta gaatactaaa aggaaaatgt 4300

 catgttaagc aatttcagaa cattaactga actattttca aagcagaaaa 4350

 attgacattg ctgcctttaa gaataccatg aatgtaagaa attgaaagaa 4400

 attgtaaaat atcacataat atagaaatgg cagttcaaag agaattgtgg 4450

 cagatgttgt gtgtgaactg ttgtttcttt gccacatgtg ttgtatttga 4500

 aagttttaca gtaagtttaa aataaaacat tctgtgactg aaaaaaaaaa 4550

 aaaaaaaaaa aaaaaaaaaa aa 4572

<210> 2961
<211> 695
<212> PRT
<213> Homo sapien

<400> 2961
 Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys
   1               5                  10                  15

 Ile Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln
                  20                  25                  30

 Arg Glu Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His
                  35                  40                  45

 Val Lys Pro Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala
                  50                  55                  60

 Phe Ala Lys Ala Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg
                  65                  70                  75

 Lys Gly Ile Val Arg Val Val Phe Phe Pro Phe Phe Phe Arg Trp
                  80                  85                  90

 Trp Leu Gln Val Thr Ser Lys Val Ile Phe Phe Trp Leu Leu Val
                  95                 100                 105

 Leu Tyr Leu Leu Gln Val Ala Ala Ile Val Leu Phe Cys Ser Thr
                 110                 115                 120

 Ser Ser Pro His Ser Ile Pro Leu Thr Glu Val Ile Gly Pro Ile
                 125                 130                 135

 Trp Leu Met Leu Leu Leu Gly Thr Val His Cys Gln Ile Val Ser
                 140                 145                 150

 Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr Gly Gly Lys Arg Arg
                 155                 160                 165

 Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val His Arg Glu Gly
                 170                 175                 180

 Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly Ala Val Gln
                 185                 190                 195

 Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val Phe Arg
                 200                 205                 210

 Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys Ala
                 215                 220                 225

 Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val
                 230                 235                 240

 Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile
                 245                 250                 255

 Gln Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr
                 260                 265                 270

 Ala Trp Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr
                 275                 280                 285

 Gln Arg Thr Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu
                 290                 295                 300

 Gly Pro Glu Thr Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr
                 305                 310                 315

 Ser Glu Gly Val Leu Arg Asn Arg Lys Ser His His Tyr Lys Lys
                 320                 325                 330

 His Tyr Pro Asn Glu Asp Ala Pro Lys Ser Gly Thr Ser Cys Ser
                 335                 340                 345

 Ser Arg Cys Ser Ser Ser Arg Gln Asp Ser Glu Ser Ala Arg Pro
                 350                 355                 360

 Glu Ser Glu Thr Glu Asp Val Leu Trp Glu Asp Leu Leu His Cys
                 365                 370                 375

 Ala Glu Cys His Ser Ser Cys Thr Ser Glu Thr Asp Val Glu Asn
                 380                 385                 390

 His Gln Ile Asn Pro Cys Val Lys Lys Glu Tyr Arg Asp Asp Pro
                 395                 400                 405

 Phe His Gln Ser His Leu Pro Trp Leu His Ser Ser His Pro Gly
                 410                 415                 420

 Leu Glu Lys Ile Ser Ala Ile Val Trp Glu Gly Asn Asp Cys Lys
                 425                 430                 435

 Lys Ala Asp Met Ser Val Leu Glu Ile Ser Gly Met Ile Met Asn
                 440                 445                 450

 Arg Val Asn Ser His Ile Pro Gly Ile Gly Tyr Gln Ile Phe Gly
                 455                 460                 465

 Asn Ala Val Ser Leu Ile Leu Gly Leu Thr Pro Phe Val Phe Arg
                 470                 475                 480

 Leu Ser Gln Ala Thr Asp Leu Glu Gln Leu Thr Ala His Ser Ala
                 485                 490                 495

 Ser Glu Leu Tyr Val Ile Ala Phe Gly Ser Asn Glu Asp Val Ile
                 500                 505                 510

 Val Leu Ser Met Val Ile Ile Ser Phe Val Val Arg Val Ser Leu
                 515                 520                 525

 Val Trp Ile Phe Phe Phe Leu Leu Cys Val Ala Glu Arg Thr Tyr
                 530                 535                 540

 Lys Gln Arg Leu Leu Phe Ala Lys Leu Phe Gly His Leu Thr Ser
                 545                 550                 555

 Ala Arg Arg Ala Arg Lys Ser Glu Val Pro His Phe Arg Leu Lys
                 560                 565                 570

 Lys Val Gln Asn Ile Lys Met Trp Leu Ser Leu Arg Ser Tyr Leu
                 575                 580                 585

 Lys Arg Arg Gly Pro Gln Arg Ser Val Asp Val Ile Val Ser Ser
                 590                 595                 600

 Ala Phe Leu Leu Thr Ile Ser Val Val Phe Ile Cys Cys Ala Gln
                 605                 610                 615

 Ile Asn Leu Tyr Leu Lys Met Glu Lys Lys Pro Asn Lys Lys Glu
                 620                 625                 630

 Glu Leu Thr Leu Val Asn Asn Val Leu Lys Leu Ala Thr Lys Leu
                 635                 640                 645

 Leu Lys Glu Leu Asp Ser Pro Phe Arg Leu Tyr Gly Leu Thr Met
                 650                 655                 660

 Asn Pro Leu Leu Tyr Asn Ile Thr Gln Val Val Ile Leu Ser Ala
                 665                 670                 675

 Val Ser Gly Val Ile Ser Asp Leu Leu Gly Phe Asn Leu Lys Leu
                 680                 685                 690

 Trp Lys Ile Lys Ser
                 695

<210> 2962
<211> 3515
<212> DNA
<213> Homo sapien

<400> 2962
 tgcacacctg taatcccagc tattcggctg aggcacgaga atcatttgaa 50

 cccaggacac ggagattgca gtgagccaag atcacaccac tgcactccag 100

 cctgggcaac agaacgagat tctgtcttaa atgaatgagt gaatgaatga 150

 agtgaattac aaaaaatttt aaaatacaaa ccaaatgttt tgttaaattc 200

 aacagacata attatgtgtc agctgcatgc agtggctcat gcctgtaatc 250

 ccaacacttt gggaggaatt acagggacca ggagtttgag actagcttgg 300

 ccaacatagt gaaaccccat ctctaccaaa aaatataaaa attagccaag 350

 tatggtggca tatgcctata ttctagctac tcaggaggct gagatgggag 400

 agtcgcttaa acccaggagg tggaggttga aatgagctga gatcatgcca 450

 ctgcactcca gcccaggtga cagagggaga ctctctcaaa gaaaaaggaa 500

 aaaaaattac tgtgtctaat ttctataaaa tttttttttt tacttattct 550

 caatttctgt acttgtggat cagtagcaaa cttcatggac tggcatcagt 600

 atgaatgaca tttgagtagc actgtttggt gtgcagcata ctagagtagt 650

 gagagaagga aacatctgtg gacattgtat caactgggag gccaccgaac 700

 attttgtcat gtttgttgaa taacttatgc agcctaaggc agcctgtcag 750

 ggcagtggtg tggcaaagcc ataatatttg tatggggctc attctactga 800

 gaggcatatc tgctgttctg atagtgtagt ctcctccatt tttcctccag 850

 cactctgctc tttgggaggc actgcagggt ggctgtgact ttggtcaggt 900

 gtagcttatg tttggccatc tcttggttga tccagtttat ttgtcttagt 950

 ttcagtgatg gccagagggt tacaaaggat ttggaatgga gcatgtctca 1000

 gggtgatgtg aactctgttg ttgcctggat ttccagatca tgtgacagag 1050

 aatcagctgg atcatttcag ctgtccaggt tatcagttag aataaagttt 1100

 ttaaaaacta aaatcttggg agcaaggagg cctctctgat gtaaagaaag 1150

 atgagtagac tggtttatcc cttctatgca gttagtacat gagagtaccc 1200

 tggtccttta agagccagag ttctttgggg tttttgtttg ttttccccca 1250

 ttaaaaagca ctagcattta ttaggggaaa atgaggttct cctcaactca 1300

 tgttttccct ctctgtattg tggaaaatct gaacctcact ctgaaagtga 1350

 atacatccat ttgaaaggga tggcaggtta ccaagagtgt catttaatga 1400

 aacccctctt tttcttgacc aaaagagacc ttgttttctt tgagaagcag 1450

 gagttcactt taatttttat gaacatctca caccacttcc acctaaccct 1500

 acctactgta atatgggctg gcctgtcaag tcttgggcaa gaatagtgat 1550

 aagatgctat caggtcagaa cccatattgt tagagtagct gaaagattca 1600

 ggagttctta ttttgaactc ttgcatgtag aatcattaca agatgtctct 1650

 taaatgcagt tagagtgaga ggaaagctgg agctgtgggt ggggaacatg 1700

 tcagaggtgg ggctcagcag gaagtgggac cagtgcctgc tggatgtggt 1750

 agataagtac cggttttgga ttagggattg ttttctcact taccttcttt 1800

 aaaaaaagaa tgtggccatt agcctttggt tctggcatgg cattaggaat 1850

 ggcttattcc agcagtcagc atgatttcca ggttccatgt cttctacatg 1900

 gaaaacatgt caaaggacag gagcagtgac cacctgacaa catcgcagtg 1950

 ggaggaaaag agaaatcatg tttattcctc aggaatgctg aagtaccctg 2000

 gagtaagctg tcattcttat tataacaatg ttattagtaa tgctttaaac 2050

 tccagcacac ttgttatgta tttgaaacca agtctgtttc ttgttttgta 2100

 ttttctctct ggaaattgta aggcggtggt cttaaataca ttaaacaaaa 2150

 ataggaaaaa aagcagttaa aatttgatgg catatcagcc agctgaccca 2200

 attcttggca cagtcaacaa gtatctttga tttgttttca gcagggctaa 2250

 gtcatcagat atgtcagaag gggtaaaaaa aaaaaacacc tgtcttttag 2300

 tcatttcttt gctgtcccaa aaatctaagt attatagtga gtaacattag 2350

 cttgcagttt ttaatagttc atcaataagt ctgaatcctt gtcagttgcc 2400

 acactggcta cccagaaaat ttcaggcagt tatatgcctc aggcagttat 2450

 atgaaggttt atttccttct tatacattaa aaatagtgtg aaacatgatt 2500

 gaaaatacac tgttttagtc tcttgatttt gtatccactt tcaacatttt 2550

 aatatgaaac cttgacagag actttgctgt aattttggtc ttgaggggcg 2600

 gggggactca tccaactcac agtacccagc agtctgagtt cttcagatag 2650

 gcataaagaa acgagaagtt acataatttt tgttgaatgg gtatggtgat 2700

 gttggcaaat gattaagcct aagaaaaact gtttgtgtac caggcacctg 2750

 taatcccagc tactcgggag ggtgaggcag gagaatcact tcaacccagg 2800

 aggcagaggc tacagtgagc tgagatcgta ccacagcact gcatcctggg 2850

 cgacagagtg agtgagactc tgtctcaaaa aaaaaaaaaa aaaaaaacag 2900

 aaaagctaca aaacattcac acattttgtt gttttctatg tctctgtata 2950

 aatgatgagc tttaaagtta atcctcaatt ttaaatatac aaaattttta 3000

 atttgtactt ttgataccat gcacttttgg aaatttttta ttttttgaga 3050

 gcatgatact tatttcttac gctcatgttt gaaaaggttt agaaatgtgg 3100

 ttgctaaatt agttttaaaa caacaactgt gactgtttta cctgtgtcca 3150

 acatgttgag aactcaaaaa gtagtaaatc gggctgtctt aatagtgcgc 3200

 ctgttactaa tggaatttac ttaaaaagta agtttgccat atgaaagggt 3250

 attaatatcc ttttcaagca taacatacaa atgaattttc atcttaaata 3300

 tattaacttc tgataagaaa acagatgcta ggcctaaaga tatttgctac 3350

 ataggaaaaa tgatttttaa aaaatttgtc tggggtgcct gtagtcccag 3400

 ctactcggga ggctgaggca ggggaatggc gtgaatccgg gaggcgggtc 3450

 ttgcagtgag cagagatcgc gccaccgcac tccagcctcg ccgacaaagc 3500

 gagactctgt gtcaa 3515

<210> 2963
<211> 1380
<212> DNA
<213> Homo sapien

<400> 2963
 cgttccgtta gcggcgtggg gttggctgca gtggcagtgc tttctcttct 50

 gctcacgggg acccgctcag gctggaggcc agccagctct tgccgccacc 100

 tcggtcgcga tgggggcgca ggaccggccg cagtgccact tcgacatcga 150

 gatcaaccgg gagccggttg gtcgcattat gtttcagctc ttctcagaca 200

 tatgtccaaa aacatgcaaa aacttccttt gcttgtgctc aggagagaaa 250

 ggccttggga aaacaactgg gaagaagtta tgttataaag gttctacgtt 300

 ccatcgtgtg gttaaaaact ttatgattca gggtggggac ttcagtgaag 350

 gtaatggaaa aggtggagaa tcaatttatg gtggatattt taaagagaat 400

 gtggtctttt gcaaaatgaa aagatgaaaa ctttattctc aaacatgaca 450

 gagcgttcct tttatcaatg gcaaatcgag ggaaacatac caatggttcc 500

 cagtttttca taaagagtgt tacaccgtgc gctccaaagt accacaaagc 550

 ctgctccaca cctggatggg gtgcatgtag tctttggact ggttatttct 600

 ggttttgaag taatcgaaca aattgaaaat ctgaagaccg atgctgcaag 650

 cagaccatat gcagatgtgc gagttattga ctgtggagta cttgccacaa 700

 aatcaataaa cagatgtctt tgagaaacac accaggaaga aaacaatcat 750

 tcagaaggct cggattcctc ttccaattcc tcctcttctt cagaatcatc 800

 ttcagaaagt gaactttgaa catgagagaa gcagaaggag gaaacataag 850

 aggaggccaa aaagttaaac gttctaaaaa gaggcgaaag gaagcaagca 900

 gttcagaaga gccaaggaat aaacatgcaa tgaacccaaa aggtcactct 950

 gagaggagtg ataccaatga aaaaaggtca gttgattcca gtgctaaaag 1000

 ggaaaaacct gtggtccgcc cagaagagat tcctccagtg cctgagaacc 1050

 gatttttact gagaagagat atgcctgttg ttactgcaga acctgaacca 1100

 ttcctgatgt tgcacccatt gtaagtgatc agaaaccatc tgtatcaaag 1150

 tctggacgga agattaaagg aaggggcaca attcgctatc acacacctcc 1200

 aagatcaaga tcctgttctg agtcagatga tgatgacagc agtgaaactc 1250

 ctcctcactg gaaagaggaa atgcagagat taagagcata tagaccacct 1300

 agtggagaaa aatggagtaa aggagataag ttaagtgacc cctgttcaag 1350

 ccgatgggat gaaagaagct tgtctcagag 1380

<210> 2964
<211> 141
<212> PRT
<213> Homo sapien

<400> 2964
 Val Pro Leu Ala Ala Trp Gly Trp Leu Gln Trp Gln Cys Phe Leu
   1               5                  10                  15

 Phe Cys Ser Arg Gly Pro Ala Gln Ala Gly Gly Gln Pro Ala Leu
                  20                  25                  30

 Ala Ala Thr Ser Val Ala Met Gly Ala Gln Asp Arg Pro Gln Cys
                  35                  40                  45

 His Phe Asp Ile Glu Ile Asn Arg Glu Pro Val Gly Arg Ile Met
                  50                  55                  60

 Phe Gln Leu Phe Ser Asp Ile Cys Pro Lys Thr Cys Lys Asn Phe
                  65                  70                  75

 Leu Cys Leu Cys Ser Gly Glu Lys Gly Leu Gly Lys Thr Thr Gly
                  80                  85                  90

 Lys Lys Leu Cys Tyr Lys Gly Ser Thr Phe His Arg Val Val Lys
                  95                 100                 105

 Asn Phe Met Ile Gln Gly Gly Asp Phe Ser Glu Gly Asn Gly Lys
                 110                 115                 120

 Gly Gly Glu Ser Ile Tyr Gly Gly Tyr Phe Lys Glu Asn Val Val
                 125                 130                 135

 Phe Cys Lys Met Lys Arg
                 140

<210> 2965
<211> 2476
<212> DNA
<213> Homo sapien

<400> 2965
 gctcctccta ctgccttctg tgctagggaa cacttcctgt ttgagtggga 50

 cctgagtttt gaaagcgtct tctgctcctc ttcatctggt ccctttcctt 100

 ccaagacccc agagaggaag gcatgcggtg ggccccagcc ctgcttctag 150

 ctttcctgcc tcttgccagt cagaaatctt ccaacttgca agggagaagg 200

 aagtcagtca ccaggccagc tgggtcatct gctgtaatca cttgtgatct 250

 tactgtaata aataccttct acatccactg gtacctgcac caggcgggga 300

 aggccccaca gcatcttcca tactatgacc cctactactc cagggttgtg 350

 ttggaatcaa gaatcagtag aggaaagtat tttacttatg caagcatgag 400

 gaggagctgg aaattgatac tgcaaaatct aattgaaaat gattctggat 450

 ctattactgt gccacctggg acaggcacag tgattcacac ctgccctaca 500

 ccacactgaa aatctgcctt gtgactgttt ctggtacaca agatagacca 550

 gccccctctc atttgttgcc accgaattta ctgtattctg tacaaagaga 600

 aacacagcat aattcctgat ctctccccta atatcacact ctcctggcag 650

 cagctgcacc ttgttcccca ccctccccca ggactttcct gaagacaagc 700

 tgtcatcttc aggcctcagc caagcagcct ggctgagagc aagactctct 750

 cagctctccg aggacatggg ggaggcccac tcactctgct tcctcggacc 800

 aacaggtaca cctagggtcc aactgcgaag cgagatattt tggacagcaa 850

 atgggaagga tatttatact gaatcatata tctagagatc acagctgaga 900

 gtgttgctta ttctttatgt ctataacaat ataagcaata gtataattac 950

 cactaaaaca ctaagcctag gtatgcagtt gaacattgtc tccctctgct 1000

 ttcctttttg tctctctctc tactttcttg gttacttgct atttttctac 1050

 acatcccttt ttctggcctc ccctccctcc ctccctagct ccctccctag 1100

 cttgccttcc ttccttcctt ccttccttcc tttcttcctc cctctctcct 1150

 tcccttcctt acttccttcc tttctttctt cctccctctc tccttccctt 1200

 ccttacttcc ttcctttctt tcttcctccc tctctccttc ccttccttac 1250

 ttccttcctt tcttcctccc tccctctctt acttccttct ttttttcctt 1300

 tcttcctttt ctctctcttt ctttcttttt tgggcacaca atcagaatac 1350

 agaatcattc tctatatgtt catgccaact ttgatacagc tagtttattc 1400

 gttcagtttt catttttata ttttggaaat ctgttgtatt attttgattt 1450

 gtatatgtaa aacctttaca tggaactgaa gtcaaaatta taaaacaaga 1500

 tcaatttaga gattttagct tccattctag aattctcttt tctcttctgt 1550

 gtctcaccct ataggtaaca atatctttat tagttcagtt gaactttttc 1600

 ttatttattc agaagtctat cgctattaca gaaatacctc ttttgcttgt 1650

 catatatgtg cagtatgcat tatttctatt tgaatggcat atttatgttt 1700

 ttgttctgat attctgtttt tatacatttc aatcaatctt ttagtttctg 1750

 gtgtctggat tttgtgtcct acttggaaag gtgaacatac ttcagaagta 1800

 tgcctaaaga aattcatatc atttcattaa tattttattc atttattact 1850

 tgatatgatc tatctggaat ttttatacaa taattactat agcaataata 1900

 ataatactga tgataaatat gggtactgac tttccggtag ttactgtact 1950

 aagcacatta catgtatatt ttatttaatc ttcacagaaa ccttatcaac 2000

 gggtttaagt aacattgaat atagcagatg agaaagtgag gggttaacta 2050

 acattcccta agtcatatag tttaatttga tagcaattgc aatccaagct 2100

 ctggggttca gaaaatgaga tttgttcatt caatttgcat tttcttatct 2150

 ttatgaatac tagcattatt ttacaatttt ataggtcatt tatacttctt 2200

 cttttgtgaa ttgccttttc atactgtttg cctatccttc tgttggggta 2250

 ttaatttttt cttatttgtt tgtaagaatt aatatacacc attttcgaga 2300

 tattgatcct ttatcaaacg tgttgaaaat atttctcatc atttgctatt 2350

 atttattttc agcacctttt ggtgaactga actttgtata ttacttttaa 2400

 taaaatctat caattttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2450

 aaaaaaaaaa aaaaaaaaaa aaaaaa 2476

<210> 2966
<211> 128
<212> PRT
<213> Homo sapien

<400> 2966
 Met Arg Trp Ala Pro Ala Leu Leu Leu Ala Phe Leu Pro Leu Ala
   1               5                  10                  15

 Ser Gln Lys Ser Ser Asn Leu Gln Gly Arg Arg Lys Ser Val Thr
                  20                  25                  30

 Arg Pro Ala Gly Ser Ser Ala Val Ile Thr Cys Asp Leu Thr Val
                  35                  40                  45

 Ile Asn Thr Phe Tyr Ile His Trp Tyr Leu His Gln Ala Gly Lys
                  50                  55                  60

 Ala Pro Gln His Leu Pro Tyr Tyr Asp Pro Tyr Tyr Ser Arg Val
                  65                  70                  75

 Val Leu Glu Ser Arg Ile Ser Arg Gly Lys Tyr Phe Thr Tyr Ala
                  80                  85                  90

 Ser Met Arg Arg Ser Trp Lys Leu Ile Leu Gln Asn Leu Ile Glu
                  95                 100                 105

 Asn Asp Ser Gly Ser Ile Thr Val Pro Pro Gly Thr Gly Thr Val
                 110                 115                 120

 Ile His Thr Cys Pro Thr Pro His
                 125

<210> 2967
<211> 1195
<212> DNA
<213> Homo sapien

<400> 2967
 ggcacgaggc gccagtcccc taaccctgag gctgccgcgc ggcggtcact 50

 gcgccggggt agtgggcccc agtgttgcgc tctctggccg ttccttacac 100

 tttgcttcag gctccagtgc aggggcgtag tgggatatgg ccaactcggg 150

 ctgcaaggac gtcacgggtc cagatgagga gagttttctg tactttgcct 200

 acggcagcaa cctgctgaca gagaggatcc acctccgaaa cccctcggcg 250

 gcgttcttct gtgtggcccg cctgcaggat tttaagcttg actttggcaa 300

 ttcccaaggc aaaacaagtc aaacttggca tggagggata gccaccattt 350

 ttcagagtcc tggcgatgaa gtgtggggag tagtatggaa aatgaacaaa 400

 agcaatttaa attctctgga tgagcaagaa ggggttaaaa gtggaatgta 450

 tgttgtaata gaagttaaag ttgcaactca agaaggaaaa gaaataacct 500

 gtcgaagtta tctgatgaca aattacgaaa gtgctccccc atccccacag 550

 tataaaaaga ttatttgcat gggtgcaaaa gaaaatggtt tgccgctgga 600

 gtatcaagag aagttaaaag caatagaacc aaatgactat acaggaaagg 650

 tctcagaaga aattgaagac atcatcaaaa agggggaaac acaaactctt 700

 tagaacataa cagaatatat ctaagggtat tctatgtgct aatataaaat 750

 atttttaaca cttgagaaca gggatctggg ggatctccac gtttgatccg 800

 ttttcagcag tgctctgaag gagtatctta cttgggtgat tccttgtttt 850

 tagactataa aaagaaactg ggataggagt tagacaattt aaaaggggtg 900

 tatgagggcc tgaaatatgt gacaaatgaa tgtgagtacc ccttctgtga 950

 acactgaaag ctattctctt gaattgatct taagtgtctc cttgctctgg 1000

 taaaagatag atttgtagct cacttgatga tggtgctggt gaattgctct 1050

 gctctgtctg agatttttaa aaatcagctt aatgagagta atctgcagac 1100

 aattgataat aacattttga aaattggaaa gatggtatac tgtttttaga 1150

 ggaataaacg tatttgtggt ttaaaaaaaa aaaaaaaaaa aaaaa 1195

<210> 2968
<211> 188
<212> PRT
<213> Homo sapien

<400> 2968
 Met Ala Asn Ser Gly Cys Lys Asp Val Thr Gly Pro Asp Glu Glu
   1               5                  10                  15

 Ser Phe Leu Tyr Phe Ala Tyr Gly Ser Asn Leu Leu Thr Glu Arg
                  20                  25                  30

 Ile His Leu Arg Asn Pro Ser Ala Ala Phe Phe Cys Val Ala Arg
                  35                  40                  45

 Leu Gln Asp Phe Lys Leu Asp Phe Gly Asn Ser Gln Gly Lys Thr
                  50                  55                  60

 Ser Gln Thr Trp His Gly Gly Ile Ala Thr Ile Phe Gln Ser Pro
                  65                  70                  75

 Gly Asp Glu Val Trp Gly Val Val Trp Lys Met Asn Lys Ser Asn
                  80                  85                  90

 Leu Asn Ser Leu Asp Glu Gln Glu Gly Val Lys Ser Gly Met Tyr
                  95                 100                 105

 Val Val Ile Glu Val Lys Val Ala Thr Gln Glu Gly Lys Glu Ile
                 110                 115                 120

 Thr Cys Arg Ser Tyr Leu Met Thr Asn Tyr Glu Ser Ala Pro Pro
                 125                 130                 135

 Ser Pro Gln Tyr Lys Lys Ile Ile Cys Met Gly Ala Lys Glu Asn
                 140                 145                 150

 Gly Leu Pro Leu Glu Tyr Gln Glu Lys Leu Lys Ala Ile Glu Pro
                 155                 160                 165

 Asn Asp Tyr Thr Gly Lys Val Ser Glu Glu Ile Glu Asp Ile Ile
                 170                 175                 180

 Lys Lys Gly Glu Thr Gln Thr Leu
                 185

<210> 2969
<211> 1263
<212> DNA
<213> Homo sapien

<400> 2969
 cccacgcgtc cgcccacgcg tccggctcgt tccattctcg gcggtggtac 50

 ctgctcccgg tggccctgag gacgtgtggg ccaggggcgg ccccgaaatt 100

 aggaagcgga gggggagcag tctgcaggtc tgcggggcta agtgtcgcgg 150

 cggcgcacct cgcgtcaaga atccggagga ggagactgca aggataggcc 200

 caggagtaat ggagtccaaa gaggaactag cggcaaacaa tctcaacggg 250

 gaaaatgccc aacaagaaaa cgaaggaggg gagcaggccc ccacgcagaa 300

 tgaagaagaa tcccgccatt tgggaggggg tgaaggccag aagcctggag 350

 gaaatatcag gcgggggcga gttaggcgac ttgtccctaa ttttcgatgg 400

 gccataccta ataggcatat tgagcacaat gaagcgagag atgatgtaga 450

 aaggtttgta gggcagatga tggaaatcaa gagaaagact agggaacagc 500

 agatgaggca ctatatgcgc ttccaaactc ctgaacctga caaccattat 550

 gacttttgcc tcataccttg aatcctaaaa gttttcgctg aggttaatgt 600

 gaacactgct ttacaagctt gtatttttgt gatttacttt ttctgtaagc 650

 cttttggggt ttacacttac cagtttctaa tggaaattag aattctaatt 700

 gaatattgtt ttgtctcagc ctaaaagtta cggtcagcat ggcaattcac 750

 ctattttagg aaaaatactc ttttcataat atgaaatgca taaagcagtt 800

 caaaaagcag tctgtattcc atcatcttcc tttttcattc cagtccttat 850

 ttttgtaagt attacttttc ctcctccggc tacctggact caaaatctca 900

 gttgtctttg acagtttttt tcttgtccct gaccaaaaaa gaatgatcat 950

 acccagaatt caatgtttga tattttaaga atgtatgttc tagtgttttt 1000

 cagagtgagt ctaccatctg tataaaaaca ccttgggggc aggcaggggc 1050

 atttaaaaat gtaggaccta tcgtccagac tcacagagtg gggctccaga 1100

 atctccattt ttaacaaact ctcttaagta attctgatgt gtaccaaaat 1150

 cagtgccatt ggtgtgtgtg tacgtaacta tatacatatg tgtgtgtgtg 1200

 tatatatata atgtgtcata accgtaaaca ataaacaata tcaagataaa 1250

 aaaaaaaaaa aaa 1263

<210> 2970
<211> 120
<212> PRT
<213> Homo sapien

<400> 2970
 Met Glu Ser Lys Glu Glu Leu Ala Ala Asn Asn Leu Asn Gly Glu
   1               5                  10                  15

 Asn Ala Gln Gln Glu Asn Glu Gly Gly Glu Gln Ala Pro Thr Gln
                  20                  25                  30

 Asn Glu Glu Glu Ser Arg His Leu Gly Gly Gly Glu Gly Gln Lys
                  35                  40                  45

 Pro Gly Gly Asn Ile Arg Arg Gly Arg Val Arg Arg Leu Val Pro
                  50                  55                  60

 Asn Phe Arg Trp Ala Ile Pro Asn Arg His Ile Glu His Asn Glu
                  65                  70                  75

 Ala Arg Asp Asp Val Glu Arg Phe Val Gly Gln Met Met Glu Ile
                  80                  85                  90

 Lys Arg Lys Thr Arg Glu Gln Gln Met Arg His Tyr Met Arg Phe
                  95                 100                 105

 Gln Thr Pro Glu Pro Asp Asn His Tyr Asp Phe Cys Leu Ile Pro
                 110                 115                 120

<210> 2971
<211> 2445
<212> DNA
<213> Homo sapien

<400> 2971
 cctacccgcg cgcaggccaa gttgctgaat caatggagcc ctccccaacc 50

 cgggcgttcc ccagcgaggc ttccttccca tcctcctgac caccggggct 100

 tttcgtgagc tcgtctctga tctcgcgcaa gagtgacaca caggtgttca 150

 aagacgcttc tggggagtga gggaagcggt ttacgagtga cttggctgga 200

 gcctcagggg cgggcactgg cacggaacac accctgaggc cagccctggc 250

 tgcccaggcg gagctgcctc ttctcccgcg ggttggtgga cccgctcagt 300

 acggagttgg ggaagctctt tcacttcgga ggattgctca acaaccatgc 350

 tgggcatctg gaccctccta cctctggttc ttacgtctgt tgctagatta 400

 tcgtccaaaa gtgttaatgc ccaagtgact gacatcaact ccaagggatt 450

 ggaattgagg aagactgtta ctacagttga gactcagaac ttggaaggcc 500

 tgcatcatga tggccaattc tgccataagc cctgtcctcc agatgtgaac 550

 atggaatcat caaggaatgc acactcacca gcaacaccaa gtgcaaagag 600

 gaagtgaaga gaaaggaagt acagaaaaca tgcagaaagc acagaaagga 650

 aaaccaaggt tctcatgaat ctccaacctt aaatcctgaa acagtggcaa 700

 taaatttatc tgatgttgac ttgagtaaat atatcaccac tattgctgga 750

 gtcatgacac taagtcaagt taaaggcttt gttcgaaaga atggtgtcaa 800

 tgaagccaaa atagatgaga tcaagaatga caatgtccaa gacacagcag 850

 aacagaaagt tcaactgctt cgtaattggc atcaacttca tggaaagaaa 900

 gaagcgtatg acacattgat taaagatctc aaaaaagcca atctttgtac 950

 tcttgcagag aaaattcaga ctatcatcct caaggacatt actagtgact 1000

 cagaaaattc aaacttcaga aatgaaatcc aaagcttggt ctagagtgaa 1050

 aaacaacaaa ttcagttctg agtatatgca attagtgttt gaaaagattc 1100

 ttaatagctg gctgtaaata ctgcttggtt ttttactggg tacattttat 1150

 catttattag cgctgaagag ccaacatatt tgtagatttt taatatctca 1200

 tgattctgcc tccaaggatg tttaaaatct agttgggaaa acaaacttca 1250

 tcaagagtaa atgcagtggc atgctaagta cccaaatagg agtgtatgca 1300

 gaggatgaaa gattaagatt atgctctggc atctaacata tgattctgta 1350

 gtatgaatgt aatcagtgta tgttagtaca aatgtctatc cacaggctaa 1400

 ccccactcta tgaatcaata gaagaagcta tgaccttttg ctgaaatatc 1450

 agttactgaa caggcaggcc actttgcctc taaattacct ctgataattc 1500

 tagagatttt accatatttc taaactttgt ttataactct gagaagatca 1550

 tatttatgta aagtatatgt atttgagtgc agaatttaaa taaggctcta 1600

 cctcaaagac ctttgcacag tttattggtg tcatattata caatatttca 1650

 attgtgaatt cacatagaaa acattaaatt ataatgtttg actattatat 1700

 atgtgtatgc attttactgg ctcaaaacta cctacttctt tctcaggcat 1750

 caaaagcatt ttgagcagga gagtattact agagctttgc cacctctcca 1800

 tttttgcctt ggtgctcatc ttaatggcct aatgcacccc caaacatgga 1850

 aatatcacca aaaaatactt aatagtccac caaaaggcaa gactgccctt 1900

 agaaattcta gcctggtttg gagatactaa ctgctctcag agaaagtagc 1950

 tttgtgacat gtcatgaacc catgtttgca atcaaagatg ataaaataga 2000

 ttcttatttt tcccccaccc ccgaaaatgt tcaataatgt cccatgtaaa 2050

 acctgctaca aatggcagct tatacatagc aatggtaaaa tcatcatctg 2100

 gatttaggaa ttgctcttgt cataccccca agtttctaag atttaagatt 2150

 ctccttacta ctatcctacg tttaaatatc tttgaaagtt tgtattaaat 2200

 gtgaatttta agaaataata tttatatttc tgtaaatgta aactgtgaag 2250

 atagttataa actgaagcag atacctggaa ccacctaaag aacttccatt 2300

 tatggaggat ttttttgccc cttgtgtttg gaattataaa atataggtaa 2350

 aagtacgtaa ttaaataatg tttttggtaa aaaaaaaaaa aaaaaaaaaa 2400

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 2445

<210> 2972
<211> 86
<212> PRT
<213> Homo sapien

<400> 2972
 Met Leu Gly Ile Trp Thr Leu Leu Pro Leu Val Leu Thr Ser Val
   1               5                  10                  15

 Ala Arg Leu Ser Ser Lys Ser Val Asn Ala Gln Val Thr Asp Ile
                  20                  25                  30

 Asn Ser Lys Gly Leu Glu Leu Arg Lys Thr Val Thr Thr Val Glu
                  35                  40                  45

 Thr Gln Asn Leu Glu Gly Leu His His Asp Gly Gln Phe Cys His
                  50                  55                  60

 Lys Pro Cys Pro Pro Asp Val Asn Met Glu Ser Ser Arg Asn Ala
                  65                  70                  75

 His Ser Pro Ala Thr Pro Ser Ala Lys Arg Lys
                  80                  85

<210> 2973
<211> 875
<212> DNA
<213> Homo sapien

<400> 2973
 caagtactcc aacaaaaaga gagattatgc taacaccagt gactgtggct 50

 tatagtccaa agcgatcccc taaagaaaac ttgtccccag gatttagtca 100

 tctgcttagc aaaaatgaga gcagtccaat tcgatttgat atacttttgg 150

 atgatttaga tactgttcct gtgtctacat tacaacgtac caatccaaga 200

 aagcaactcc agtttcttcc tctagatgac tcggaagaaa aaacttattc 250

 tgagaaagcc accgataacc atgttaatca tagctcttgc cctgaaccgg 300

 tgccaaatgg agtgaagaaa gtatctgtga gaacagcctg ggagaagaat 350

 aaatcagtta gctacgaaca gtgtaagccg gtttcagtca ctccacaggg 400

 gaatgatttt gaatatacag caaaaattcg gaccctagct gaaacagaac 450

 gattttttga tgaacttaca aaagaaaagg accagattga ggcagcacta 500

 agcaggatgc cttctcctgg aggacgaatc actttacaga caagattaaa 550

 tcagacccct cagatatgtg aggaatcaag ccataaatgt gcatttgctg 600

 gacattatgt accatgtcat ctctatgact acagatttca aggataattt 650

 ttacatctaa caatttcact gtaacagtga ccgataatgt gagaaatgtg 700

 ctttttacag tgctgctggt gggtagacaa gtgcttgctg cagttgtttc 750

 tgaatctagc cagatgctgg agtcgtgaag ctgtaagctc cgcgggagca 800

 gggaccatct ctctttcttg cactacaggc actcaataaa tacttgtggc 850

 tgtgaaaaaa aaaaaaaaaa aaaaa 875

<210> 2974
<211> 2970
<212> DNA
<213> Homo sapien

<400> 2974
 cgcccgagcc gcgcgcggag ctgccggggg ctccttagca cccgggcgcc 50

 ggggccctcg cccttccgca gccttcactc cagccctctg ctcccgcacg 100

 ccatgaagtc gccgttctac cgctgccaga acaccacctc tgtggaaaaa 150

 ggcaactcgg cggtgatggg cggggtgctc ttcagcaccg gcctcctggg 200

 caacctgctg gccctggggc tgctggcgcg ctcggggctg gggtggtgct 250

 cgcggcgtcc actgcgcccg ctgccctcgg tcttctacat gctggtgtgt 300

 ggcctgacgg tcaccgactt gctgggcaag tgcctcctaa gcccggtggt 350

 gctggctgcc tacgctcaga accggagtct gcgggtgctt gcgcccgcat 400

 tggacaactc gttgtgccaa gccttcgcct tcttcatgtc cttctttggg 450

 ctctcctcga cactgcaact cctggccatg gcactggagt gctggctctc 500

 cctagggcac cctttcttct accgacggca catcaccctg cgcctgggcg 550

 cactggtggc cccggtggtg agcgccttct ccctggcttt ctgcgcgcta 600

 cctttcatgg gcttcgggaa gttcgtgcag tactgccccg gcacctggtg 650

 ctttatccag atggtccacg aggagggctc gctgtcggtg ctggggtact 700

 ctgtgctcta ctccagcctc atggcgctgc tggtcctcgc caccgtgctg 750

 tgcaacctcg gcgccatgcg caacctctat gcgatgcacc ggcggctgca 800

 gcggcacccg cgctcctgca ccagggactg tgccgagccg cgcgcggacg 850

 ggagggaagc gtcccctcag cccctggagg agctggatca cctcctgctg 900

 ctggcgctga tgaccgtgct cttcactatg tgttctctgc ccgtaattta 950

 tcgcgcttac tatggagcat ttaaggatgt caaggagaaa aacaggacct 1000

 ctgaagaagc agaagacctc cgagccttgc gatttctatc tgtgatttca 1050

 attgtggacc cttggatttt tatcattttc agatctccag tatttcggat 1100

 attttttcac aagattttca ttagacctct taggtacagg agccggtgca 1150

 gcaattccac taacatggaa tccagtctgt gacagtgttt ttcactctgt 1200

 ggtaagctga ggaatatgtc acattttcag tcaaagaacc atgattaaaa 1250

 aaaaaaagac aacttacaat ttaaatcctt aaaagttacc tcccataaca 1300

 aaagcatgta tatgtatttt caaaagtatt tgatatctta acaatgtgtt 1350

 accattctat agtcatgaac cccttcagtg cattttcatt tttttattaa 1400

 cagcaactaa aattttatat attgtaacga gtgttaaaag tcttaaaaag 1450

 caatggtatt aattgtccct acatttgtgc ttggtggccc tatttttttt 1500

 ttttagagag gccttgagac atacaggtct tttaaaatac agtagaaaca 1550

 ccactgttta cgattatacg atggacattc ataaaaagca taatttctta 1600

 ccctattcat tttttggtga aacctgattc attgatttta tatcattgcc 1650

 gatgtttagt tcatttcttt gccaattgat ctaagcatag cctgaattat 1700

 gatgttcctc agagaagtga ggtgggaaat atgaccaggt caggcagttg 1750

 gaggggcttc cccagccacc atcggggagt acttgctgcc tcaggtggag 1800

 acctgaagct gtaactagat gcagagcaag atatgactat agcccacaac 1850

 ccaaagaagc aaaaattcat ttttatcttt tgaaatcgag tttcttttgt 1900

 attgagtcaa gggtgtcagt aggaatcaaa agttgggggt gggttgcaaa 1950

 atgttctttc agtttttaga acctccattt tataaaagaa ttatcctatc 2000

 aatggattct ttagtggaag gatttatgct tctttgaaaa ccagtgtgtg 2050

 actcactgta gagccatgtt tactgtttga ctgtgtggca caggggggca 2100

 tttggcacag caaaaagccc acccaggact tagcctcagt tgatgatagt 2150

 aacaatggcc ttaacatcta ccttaacagc tacctattac agccgtattc 2200

 tgctgtccgt ggagacggta agatcttagg ttccaagatt ttacttcaaa 2250

 ttacaccttc aaaactggag cagcatatag ccgaaaagga gcacaactga 2300

 gcactttaat agtaatttaa aagttttcaa gggtcagcaa tatgatgact 2350

 gaaagggaaa agtggaggaa acgcagctgc aactgaagcg gagactctaa 2400

 acccagcttg caggtaagag ctttcacctt tggtaaaaga acagctgggg 2450

 aggttcaagg ggtttcagca tctctggagt tcctttgtat ctgacaatct 2500

 caggactcca aggtgcaaag cctgctgcat ttgcgtgatc tcaagacctc 2550

 cagccagaag tcccttccaa atataagagt actcatgttt atttatttcc 2600

 aactgagcag caacctcctt tgtttcactt atgttttttc cagtatctga 2650

 gataatataa agctgggtaa ttttttatgt aattttttgg tatagcaaaa 2700

 ctgtggaaaa gccaaattag gcatacaagg agtatgattt aacagtatga 2750

 catgatgaaa aaaatacagt tgtttttgaa atttaacttt tgtttgtacc 2800

 ttcaatgtgt aagtacatgc atgttttatt gtcagaggaa gaacatgttt 2850

 tttgtattct ttttttggag aggtgtgtta ggataattgt ccagttaatt 2900

 tgaaaaggcc ccagatgaat caataaatat aattttatag taaaaaaaaa 2950

 aaaaaaaaaa aaaaaaaaaa 2970

<210> 2975
<211> 359
<212> PRT
<213> Homo sapien

<400> 2975
 Met Lys Ser Pro Phe Tyr Arg Cys Gln Asn Thr Thr Ser Val Glu
   1               5                  10                  15

 Lys Gly Asn Ser Ala Val Met Gly Gly Val Leu Phe Ser Thr Gly
                  20                  25                  30

 Leu Leu Gly Asn Leu Leu Ala Leu Gly Leu Leu Ala Arg Ser Gly
                  35                  40                  45

 Leu Gly Trp Cys Ser Arg Arg Pro Leu Arg Pro Leu Pro Ser Val
                  50                  55                  60

 Phe Tyr Met Leu Val Cys Gly Leu Thr Val Thr Asp Leu Leu Gly
                  65                  70                  75

 Lys Cys Leu Leu Ser Pro Val Val Leu Ala Ala Tyr Ala Gln Asn
                  80                  85                  90

 Arg Ser Leu Arg Val Leu Ala Pro Ala Leu Asp Asn Ser Leu Cys
                  95                 100                 105

 Gln Ala Phe Ala Phe Phe Met Ser Phe Phe Gly Leu Ser Ser Thr
                 110                 115                 120

 Leu Gln Leu Leu Ala Met Ala Leu Glu Cys Trp Leu Ser Leu Gly
                 125                 130                 135

 His Pro Phe Phe Tyr Arg Arg His Ile Thr Leu Arg Leu Gly Ala
                 140                 145                 150

 Leu Val Ala Pro Val Val Ser Ala Phe Ser Leu Ala Phe Cys Ala
                 155                 160                 165

 Leu Pro Phe Met Gly Phe Gly Lys Phe Val Gln Tyr Cys Pro Gly
                 170                 175                 180

 Thr Trp Cys Phe Ile Gln Met Val His Glu Glu Gly Ser Leu Ser
                 185                 190                 195

 Val Leu Gly Tyr Ser Val Leu Tyr Ser Ser Leu Met Ala Leu Leu
                 200                 205                 210

 Val Leu Ala Thr Val Leu Cys Asn Leu Gly Ala Met Arg Asn Leu
                 215                 220                 225

 Tyr Ala Met His Arg Arg Leu Gln Arg His Pro Arg Ser Cys Thr
                 230                 235                 240

 Arg Asp Cys Ala Glu Pro Arg Ala Asp Gly Arg Glu Ala Ser Pro
                 245                 250                 255

 Gln Pro Leu Glu Glu Leu Asp His Leu Leu Leu Leu Ala Leu Met
                 260                 265                 270

 Thr Val Leu Phe Thr Met Cys Ser Leu Pro Val Ile Tyr Arg Ala
                 275                 280                 285

 Tyr Tyr Gly Ala Phe Lys Asp Val Lys Glu Lys Asn Arg Thr Ser
                 290                 295                 300

 Glu Glu Ala Glu Asp Leu Arg Ala Leu Arg Phe Leu Ser Val Ile
                 305                 310                 315

 Ser Ile Val Asp Pro Trp Ile Phe Ile Ile Phe Arg Ser Pro Val
                 320                 325                 330

 Phe Arg Ile Phe Phe His Lys Ile Phe Ile Arg Pro Leu Arg Tyr
                 335                 340                 345

 Arg Ser Arg Cys Ser Asn Ser Thr Asn Met Glu Ser Ser Leu
                 350                 355

<210> 2976
<211> 1821
<212> DNA
<213> Homo sapien

<400> 2976
 agctctgcga ggggccggag cgcggcggag ccatgcagta cccgcacccc 50

 gggccggcgg cgggcgccgt gggggtgccg ctgtacgcgc ccacgccgct 100

 gctgcaaccc gcacacccga cgccctttta catcgaggac atcctgggcc 150

 gcgggcccgc cgcgcccacg cccgccccca cgctgccgtc ccccaactcc 200

 tccttcacca gcctcgtgtc cccctaccgg accccggtgt acgagcccac 250

 gccgatccat ccagccttct cgcaccactc cgccgccgcg ctggccgctg 300

 cctacggacc cggcggcttc gggggccctc tgtacccctt cccgcggacg 350

 gtgaacgact acacgcacgc cctgctccgc cacgaccccc tgggcaaacc 400

 tctactctgg agccccttct tgcagaggcc tctgcataaa aggaaaggcg 450

 gccaggtgag attctccaac gaccagacca tcgagctgga gaagaaattc 500

 gagacgcaga aatatctctc tccgcccgag aggaagcgtc tggccaagat 550

 gctgcagctc agcgagagac aggtcaaaac ctggtttcag aatcgacgcg 600

 ctaaatggag gagactaaaa caggagaacc ctcaaagcaa taaaaaagaa 650

 gaactggaaa gtttggacag ttcctgtgat cagaggcaag atttgcccag 700

 tgaacagaat aaaggtgctt ctttggatag ctctcaatgt tcgccctccc 750

 ctgcctccca ggaagacctt gaatcagaga tttcagagga ttctgatcag 800

 gaagtggaca ttgagggcga taaaagctat tttaatgctg gatgatgacc 850

 actggcattg gcatgttcag aaaactggat ttaggaataa tgttttgcta 900

 cagaaaatct tcatagaaga actggaaggc tatataagaa agggaatcaa 950

 ttctctggta ttctggaaac ctaaaaatat ttggtgcact gctcaattaa 1000

 caaacctaca tggagacctt aattttgact taacaaatag tttatgtact 1050

 gctcttaggt tgttttgata aagtgacatt atagtgatta aattcttccc 1100

 cctttaaaaa aacagttagt ggttttcact atttataaaa aattaatttt 1150

 gaactttttg ttaaattttt aagttatagc tttaaaggtt ttaataggac 1200

 cttcttgaac gacttttctg taatctgttt atctcccact taatggaaag 1250

 gcaaaggggt accccaaatc cagagctgcc tacatttcag gcagccttgg 1300

 agtattttaa aaggaaaaca ttctttactt ttatatgaca ttcttatact 1350

 gctgtctcaa atccaaaaac atttcagagc tcttgtctca gagatgtgtg 1400

 ttctttttgt cagagatatg gttgatgaga atcttaaatg cttgttttgc 1450

 actatcactt agtacctgtt tgaccaaggt gttaagggga tagtacctcc 1500

 caattcaagc agagaaactg acctgactaa agttaatcgc agatgaacta 1550

 gaagtcacag gttaattaaa tgtaagtaga ttgtagatac tgttttatat 1600

 caaacaatgt ttataatgtg tatatagaat tgttcactgt aaaaaaaatg 1650

 gccaaaatgt gttttttttt taataagtaa cttgactata aaataaagcc 1700

 gtccgtggga cgactgacct cgtaaaaaaa aaaaaaaaaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaaaaaaaaa aaaaaaaaaa a 1821

<210> 2977
<211> 270
<212> PRT
<213> Homo sapien

<400> 2977
 Met Gln Tyr Pro His Pro Gly Pro Ala Ala Gly Ala Val Gly Val
   1               5                  10                  15

 Pro Leu Tyr Ala Pro Thr Pro Leu Leu Gln Pro Ala His Pro Thr
                  20                  25                  30

 Pro Phe Tyr Ile Glu Asp Ile Leu Gly Arg Gly Pro Ala Ala Pro
                  35                  40                  45

 Thr Pro Ala Pro Thr Leu Pro Ser Pro Asn Ser Ser Phe Thr Ser
                  50                  55                  60

 Leu Val Ser Pro Tyr Arg Thr Pro Val Tyr Glu Pro Thr Pro Ile
                  65                  70                  75

 His Pro Ala Phe Ser His His Ser Ala Ala Ala Leu Ala Ala Ala
                  80                  85                  90

 Tyr Gly Pro Gly Gly Phe Gly Gly Pro Leu Tyr Pro Phe Pro Arg
                  95                 100                 105

 Thr Val Asn Asp Tyr Thr His Ala Leu Leu Arg His Asp Pro Leu
                 110                 115                 120

 Gly Lys Pro Leu Leu Trp Ser Pro Phe Leu Gln Arg Pro Leu His
                 125                 130                 135

 Lys Arg Lys Gly Gly Gln Val Arg Phe Ser Asn Asp Gln Thr Ile
                 140                 145                 150

 Glu Leu Glu Lys Lys Phe Glu Thr Gln Lys Tyr Leu Ser Pro Pro
                 155                 160                 165

 Glu Arg Lys Arg Leu Ala Lys Met Leu Gln Leu Ser Glu Arg Gln
                 170                 175                 180

 Val Lys Thr Trp Phe Gln Asn Arg Arg Ala Lys Trp Arg Arg Leu
                 185                 190                 195

 Lys Gln Glu Asn Pro Gln Ser Asn Lys Lys Glu Glu Leu Glu Ser
                 200                 205                 210

 Leu Asp Ser Ser Cys Asp Gln Arg Gln Asp Leu Pro Ser Glu Gln
                 215                 220                 225

 Asn Lys Gly Ala Ser Leu Asp Ser Ser Gln Cys Ser Pro Ser Pro
                 230                 235                 240

 Ala Ser Gln Glu Asp Leu Glu Ser Glu Ile Ser Glu Asp Ser Asp
                 245                 250                 255

 Gln Glu Val Asp Ile Glu Gly Asp Lys Ser Tyr Phe Asn Ala Gly
                 260                 265                 270

<210> 2978
<211> 1447
<212> DNA
<213> Homo sapien

<400> 2978
 gagatagcaa agcagagtgt ttatcttgtg agccattctc catatttcag 50

 atataagatt tcagttctca gtgagtctaa gtgacagaag gaatggagac 100

 cctcttgggc ctgcttatcc tttggctgca gctgcaatgg gtgagcagca 150

 aacaggaggt gacacagatt cctgcagctc tgagtgtccc agaaggagaa 200

 aacttggttc tcaactgcag tttcactgat agcgctattt acaacctcca 250

 gtggtttagg caggaccctg ggaaaggtct cacatctctg ttgcttattc 300

 agtcaagtca gagagagcaa acaagtggaa gacttaatgc ctcgctggat 350

 aaatcatcag gacgtagtac tttatacatt gcagcttctc agcctggtga 400

 ctcagccacc tacctctgtg ctgtgaggga caatgacatg cgctttggag 450

 cagggaccag actgacagta aaacccaata tccagaaccc tgaccctgcc 500

 gtgtaccagc tgagagactc taaatccagt gacaagtctg tctgcctatt 550

 caccgatttt gattctcaaa caaatgtgtc acaaagtaag gattctgatg 600

 tgtatatcac agacaaaact gtgctagaca tgaggtctat ggacttcaag 650

 agcaacagtg ctgtggcctg gagcaacaaa tctgactttg catgtgcaaa 700

 cgccttcaac aacagcatta ttccagaaga caccttcttc cccagcccag 750

 aaagttcctg tgatgtcaag ctggtcgaga aaagctttga aacagatacg 800

 aacctaaact ttcaaaacct gtcagtgatt gggttccgaa tcctcctcct 850

 gaaagtggcc gggtttaatc tgctcatgac gctgcggctg tggtccagct 900

 gagatctgca agattgtaag acagcctgtg ctccctcgct ccttcctctg 950

 cattgcccct cttctccctc tccaaacaga gggaactctc ccacccccaa 1000

 ggaggtgaaa gctgctacca cctctgtgcc cccccggcaa tgccaccaac 1050

 tggatcctac ccgaatttat gattaagatt gctgaagagc tgccaaacac 1100

 tgctgccacc ccctctgttc ccttattgct gcttgtcact gcctgacatt 1150

 cacggcagag gcaaggctgc tgcagcctcc cctggctgtg cacattccct 1200

 cctgctcccc agagactgcc tccgccatcc cacagatgat ggatcttcag 1250

 tgggttctct tgggctctag gtcctgcaga atgttgtgag gggtttattt 1300

 ttttttaata gtgttcataa agaaatacat agtattcttc ttctcaagac 1350

 gtggggggaa attatctcat tatcgaggcc ctgctatgct gtgtatctgg 1400

 gcgtgttgta tgtcctgctg ccgatgcctt cattaaaatg attggga 1447

<210> 2979
<211> 269
<212> PRT
<213> Homo sapien

<400> 2979
 Met Glu Thr Leu Leu Gly Leu Leu Ile Leu Trp Leu Gln Leu Gln
   1               5                  10                  15

 Trp Val Ser Ser Lys Gln Glu Val Thr Gln Ile Pro Ala Ala Leu
                  20                  25                  30

 Ser Val Pro Glu Gly Glu Asn Leu Val Leu Asn Cys Ser Phe Thr
                  35                  40                  45

 Asp Ser Ala Ile Tyr Asn Leu Gln Trp Phe Arg Gln Asp Pro Gly
                  50                  55                  60

 Lys Gly Leu Thr Ser Leu Leu Leu Ile Gln Ser Ser Gln Arg Glu
                  65                  70                  75

 Gln Thr Ser Gly Arg Leu Asn Ala Ser Leu Asp Lys Ser Ser Gly
                  80                  85                  90

 Arg Ser Thr Leu Tyr Ile Ala Ala Ser Gln Pro Gly Asp Ser Ala
                  95                 100                 105

 Thr Tyr Leu Cys Ala Val Arg Asp Asn Asp Met Arg Phe Gly Ala
                 110                 115                 120

 Gly Thr Arg Leu Thr Val Lys Pro Asn Ile Gln Asn Pro Asp Pro
                 125                 130                 135

 Ala Val Tyr Gln Leu Arg Asp Ser Lys Ser Ser Asp Lys Ser Val
                 140                 145                 150

 Cys Leu Phe Thr Asp Phe Asp Ser Gln Thr Asn Val Ser Gln Ser
                 155                 160                 165

 Lys Asp Ser Asp Val Tyr Ile Thr Asp Lys Thr Val Leu Asp Met
                 170                 175                 180

 Arg Ser Met Asp Phe Lys Ser Asn Ser Ala Val Ala Trp Ser Asn
                 185                 190                 195

 Lys Ser Asp Phe Ala Cys Ala Asn Ala Phe Asn Asn Ser Ile Ile
                 200                 205                 210

 Pro Glu Asp Thr Phe Phe Pro Ser Pro Glu Ser Ser Cys Asp Val
                 215                 220                 225

 Lys Leu Val Glu Lys Ser Phe Glu Thr Asp Thr Asn Leu Asn Phe
                 230                 235                 240

 Gln Asn Leu Ser Val Ile Gly Phe Arg Ile Leu Leu Leu Lys Val
                 245                 250                 255

 Ala Gly Phe Asn Leu Leu Met Thr Leu Arg Leu Trp Ser Ser
                 260                 265

<210> 2980
<211> 164
<212> DNA
<213> Homo sapien

<400> 2980
 accctcttca ctctttttca gccatagttc ataccgagaa ggtgaacatg 50

 atgtccctca cagtgcttgg gctacgaatg ctgtttgcaa agactgttgc 100

 cgtcaatttt ctcttgactg ccaagttatt tttcttgtaa ggtaagaatt 150

 agccgcttct tatt 164

<210> 2981
<211> 177
<212> PRT
<213> Homo sapien

<400> 2981
 Pro Ser Tyr Thr Gly Gly Tyr Ala Asp Lys Leu Ile Phe Gly Lys
   1               5                  10                  15

 Gly Thr Arg Val Thr Val Glu Pro Arg Ser Gln Pro His Thr Lys
                  20                  25                  30

 Pro Ser Val Phe Val Met Lys Asn Gly Thr Asn Val Ala Cys Leu
                  35                  40                  45

 Val Lys Glu Phe Tyr Pro Lys Asp Ile Arg Ile Asn Leu Val Ser
                  50                  55                  60

 Ser Lys Lys Ile Thr Glu Phe Asp Pro Ala Ile Val Ile Ser Pro
                  65                  70                  75

 Ser Gly Lys Tyr Asn Ala Val Lys Leu Gly Lys Tyr Glu Asp Ser
                  80                  85                  90

 Asn Ser Val Thr Cys Ser Val Gln His Asp Asn Lys Thr Val His
                  95                 100                 105

 Ser Thr Asp Phe Glu Val Lys Thr Asp Ser Thr Asp His Val Lys
                 110                 115                 120

 Pro Lys Glu Thr Glu Asn Thr Lys Gln Pro Ser Lys Ser Cys His
                 125                 130                 135

 Lys Pro Lys Ala Ile Val His Thr Glu Lys Val Asn Met Met Ser
                 140                 145                 150

 Leu Thr Val Leu Gly Leu Arg Met Leu Phe Ala Lys Thr Val Ala
                 155                 160                 165

 Val Asn Phe Leu Leu Thr Ala Lys Leu Phe Phe Leu
                 170                 175

<210> 2982
<211> 3961
<212> DNA
<213> Homo sapien

<400> 2982
 agcgggaaac gtacctaagt attattggac agccggagta ttttacagtg 50

 gttgctgctc aggaaatttg agtgaaggac tgcaaaagag gagcaaagca 100

 gacccgagag agaaggcagc agtgctcccc tgtgacgtgc tccatcaccg 150

 ggcagggaag acaccgctgc cacctctcca cagccttgtt caagagcact 200

 ggaaattgat ggtacaaaac agaagaggga acggaaaaag acagtctcat 250

 tcagcagcat gccaacagag aagaagatca gcagtgcaag tgattgtatt 300

 aattcaatgg ttgagggttc agaactcaaa aaggttcgct ccaactctag 350

 aatttatcat aggtactttt tactggatgc tgacatgcag agcctaaggt 400

 gggagccatc taagaaggat tctgagaaag ccaagattga cattaaatcc 450

 atcaaggaag tgagaacagg aaaaaacaca gacatattcc gcagcaatgg 500

 catttctgac cggatatctg aagattgtgc gttttccgtc atatatggag 550

 agaattatga gtcactggat ttggttgcca actccgcaga tgttgcaaac 600

 atctgggtta caggactgcg gtacctaatt tcttatggaa aacatacact 650

 tgatatgtta gaaagtagcc aagataacat gaggacttct tgggtttcac 700

 aaatgtttag tgaaattgat gtagataacc ttggacatat aactctgtgt 750

 aatgctgtgc aatgtatcag aaacctcaat cctggtttaa aaacgagcaa 800

 aattgagctt aagttcaaag aattgcataa atcaaaggac aaagctggta 850

 ccgaggtcac aaaggaagaa tttattgagg tttttcatga gctttgtact 900

 agacctgaaa tttatttcct tttagttcag ttttcaagca ataaagaatt 950

 ccttgatacc aaggacctta tgatgtttct tgaggcagaa cagggtgtgg 1000

 cacatataaa tgaggaaata agccttgaaa ttattcacaa atatgaacca 1050

 tccaaagagg gtcaggaaaa gggctggctc tccatagacg ggttcactaa 1100

 ttaccttatg tcacctgact gttatatatt cgatccagaa cataagaagg 1150

 tctgtcagga tatgaagcaa cctctgtctc attactttat aaactcatct 1200

 cataatacat acttaataga ggatcagttc cgaggtccct ccgacatcac 1250

 aggatatatt cgagctctta aaatgggttg ccggagtgtt gaattagatg 1300

 tatgggatgg gccggacaat gaacctgtaa tttacacagg ccacaccatg 1350

 acctctcaga tagttttccg cagtgtcatt gatattatta acaagtatgc 1400

 attctttgct tcagagtatc ctcttatctt gtgtttagaa aaccactgtt 1450

 ccattaaaca acagaaggta atggttcagc acatgaagaa acttttagga 1500

 gacaagctct atacaacatc acccaatgtt gaggaatctt atctaccatc 1550

 cccagatgtc ctgaaaggga aaatactaat taaagcaaag aagctgtcct 1600

 caaattgctc tggggtagaa ggagatgtta ctgacgaaga tgaaggagca 1650

 gaaatgtctc agaggatggg aaaagagaac atggagcaac ccaataatgt 1700

 gcctgtgaag cgatttcagc tttgtaaaga actgtctgaa ctggtcagca 1750

 tctgcaaatc agttcagttc aaagaatttc agatgtcgtt tcaggttcag 1800

 aagtactggg aagtctgttc ctttaatgaa gtgcttgcca gcaagtacgc 1850

 caatgaaaat ccaggggact ttgtaaatta caacaaacgt tttcttgcta 1900

 gggtttttcc cagtccaatg agaattgatt ccagtaacat gaatcctcaa 1950

 gatttttgga aatgtggttg ccaaattgta gccatgaact ttcagacacc 2000

 aggactgatg atggacctga atattggctg gtttaggcag aacggaaact 2050

 gtggctatgt cctccggcca gccatcatga gggaggaggt ctccttcttc 2100

 agcgtcaata caaaagactc tgtcccaggg gtctcacctc aacttcttca 2150

 cattaaaatc atcagtgggc agaactttcc caagcccaaa ggatcaggtg 2200

 ccaaaggtga tgtggtagat ccttatgtct atgttgaaat ccatggaatc 2250

 cctgctgatt gtgcagaaca aaggacaaaa acagtgcacc agaatggaga 2300

 cgctcacatt tttgatgaaa gctttgaatt tcaaatcaac ctgcctgaac 2350

 tggccatggt gcgctttgta gtgctggatg atgactacat tggggatgaa 2400

 ttcatcggcc agtacacaat tccctttgaa tgtttacaga cgggctaccg 2450

 ccatgtcccc ctgcagtcct taactggaga ggtccttgca catgcttctt 2500

 tatttgtcca cgtggctatt actaaccgaa gaggaggagg aaagcctcgt 2550

 aaaaggggcc tttctgtgag aaaagggaag aaatccaggg aatatgcatc 2600

 tttgagaaca ctgtggatta aaaccgtgga tgaggtattc aagaatgccc 2650

 agccccctat acgggatgcc acagatctga gagaaaacat gcagaatgcg 2700

 gtggtgtcat tcaaggagct gtgtggcctc tcctctgtgg ccaatctcat 2750

 gcagtgcatg ttggcggtgt ctccccgctt tctggggccc gataacacac 2800

 ccctagtggt cctaaatctc agcgagcagt accccacaat ggagctgcag 2850

 ggaattgtgc cggaggttct gaagaagatc gtaacaactt atgacatgat 2900

 gattcagtcc ctcaaggcgt tgattgaaaa tgcagatgct gtatatgaaa 2950

 agatcgtaca ttgtcagaag gcagccatgg aattccatga acacttgcac 3000

 agcataggca ccaaggaagg tttgaaggaa agaaaactac aaaaagcagt 3050

 ggagagcttt acctggaata ttaccatctt aaagggacaa gcagatcttt 3100

 tgaaatatgc taagaatgag acattggaga acctgaaaca aatccatttt 3150

 gctgctgttt catgtggact gaataaacca ggcaccgaaa atgctgatgt 3200

 ccagaagcca cgccggagct tggaagtcat acccgaaaaa gcaaacgatg 3250

 aaactggaga atgaggaaac ttacaataaa ccattatgga gtttataact 3300

 ctaggaccaa ttgtagtcag atgggacatt tgctttgcac tcactaatga 3350

 gaataatatt cgggatttta aagcacaact ggaatagcta attacagtct 3400

 attaaaactg tgaatgtatg tagcaatcgt gcgtgtgaag gcaaataaac 3450

 tctttaacag gcaattatat tgctggccaa aatatgctat atttgtatac 3500

 aaagacattc taactcagtt ccagtatgaa gaaagattat tcactctagc 3550

 tccactgaga aacattttcc taagtgaaaa caatttctta agatggaaat 3600

 ggattggatt gtcaaattat tatttattgg agaaaaaaac ctgatctaca 3650

 catttttact tatatggggt tgccagagtc tctgggttct agatgatttt 3700

 ggtggcatgc ttgctgagcc ataattacta aagagaatgt aagtggacgg 3750

 gttccctgaa tccccggggt ccttggagag ccatcgagga gaatgtgcaa 3800

 ttggactgaa gctccctggc tgaagataca tgccgagtca gcacatgggt 3850

 agagatgatg taaaagcagc caatctggaa acaatacatt gtaaatagtt 3900

 tttcattgta tgaagtagtg ttcacattaa aaagatgttt tatgacaaaa 3950

 aaaaaaaaaa a 3961

<210> 2983
<211> 1001
<212> PRT
<213> Homo sapien

<400> 2983
 Met Pro Thr Glu Lys Lys Ile Ser Ser Ala Ser Asp Cys Ile Asn
   1               5                  10                  15

 Ser Met Val Glu Gly Ser Glu Leu Lys Lys Val Arg Ser Asn Ser
                  20                  25                  30

 Arg Ile Tyr His Arg Tyr Phe Leu Leu Asp Ala Asp Met Gln Ser
                  35                  40                  45

 Leu Arg Trp Glu Pro Ser Lys Lys Asp Ser Glu Lys Ala Lys Ile
                  50                  55                  60

 Asp Ile Lys Ser Ile Lys Glu Val Arg Thr Gly Lys Asn Thr Asp
                  65                  70                  75

 Ile Phe Arg Ser Asn Gly Ile Ser Asp Arg Ile Ser Glu Asp Cys
                  80                  85                  90

 Ala Phe Ser Val Ile Tyr Gly Glu Asn Tyr Glu Ser Leu Asp Leu
                  95                 100                 105

 Val Ala Asn Ser Ala Asp Val Ala Asn Ile Trp Val Thr Gly Leu
                 110                 115                 120

 Arg Tyr Leu Ile Ser Tyr Gly Lys His Thr Leu Asp Met Leu Glu
                 125                 130                 135

 Ser Ser Gln Asp Asn Met Arg Thr Ser Trp Val Ser Gln Met Phe
                 140                 145                 150

 Ser Glu Ile Asp Val Asp Asn Leu Gly His Ile Thr Leu Cys Asn
                 155                 160                 165

 Ala Val Gln Cys Ile Arg Asn Leu Asn Pro Gly Leu Lys Thr Ser
                 170                 175                 180

 Lys Ile Glu Leu Lys Phe Lys Glu Leu His Lys Ser Lys Asp Lys
                 185                 190                 195

 Ala Gly Thr Glu Val Thr Lys Glu Glu Phe Ile Glu Val Phe His
                 200                 205                 210

 Glu Leu Cys Thr Arg Pro Glu Ile Tyr Phe Leu Leu Val Gln Phe
                 215                 220                 225

 Ser Ser Asn Lys Glu Phe Leu Asp Thr Lys Asp Leu Met Met Phe
                 230                 235                 240

 Leu Glu Ala Glu Gln Gly Val Ala His Ile Asn Glu Glu Ile Ser
                 245                 250                 255

 Leu Glu Ile Ile His Lys Tyr Glu Pro Ser Lys Glu Gly Gln Glu
                 260                 265                 270

 Lys Gly Trp Leu Ser Ile Asp Gly Phe Thr Asn Tyr Leu Met Ser
                 275                 280                 285

 Pro Asp Cys Tyr Ile Phe Asp Pro Glu His Lys Lys Val Cys Gln
                 290                 295                 300

 Asp Met Lys Gln Pro Leu Ser His Tyr Phe Ile Asn Ser Ser His
                 305                 310                 315

 Asn Thr Tyr Leu Ile Glu Asp Gln Phe Arg Gly Pro Ser Asp Ile
                 320                 325                 330

 Thr Gly Tyr Ile Arg Ala Leu Lys Met Gly Cys Arg Ser Val Glu
                 335                 340                 345

 Leu Asp Val Trp Asp Gly Pro Asp Asn Glu Pro Val Ile Tyr Thr
                 350                 355                 360

 Gly His Thr Met Thr Ser Gln Ile Val Phe Arg Ser Val Ile Asp
                 365                 370                 375

 Ile Ile Asn Lys Tyr Ala Phe Phe Ala Ser Glu Tyr Pro Leu Ile
                 380                 385                 390

 Leu Cys Leu Glu Asn His Cys Ser Ile Lys Gln Gln Lys Val Met
                 395                 400                 405

 Val Gln His Met Lys Lys Leu Leu Gly Asp Lys Leu Tyr Thr Thr
                 410                 415                 420

 Ser Pro Asn Val Glu Glu Ser Tyr Leu Pro Ser Pro Asp Val Leu
                 425                 430                 435

 Lys Gly Lys Ile Leu Ile Lys Ala Lys Lys Leu Ser Ser Asn Cys
                 440                 445                 450

 Ser Gly Val Glu Gly Asp Val Thr Asp Glu Asp Glu Gly Ala Glu
                 455                 460                 465

 Met Ser Gln Arg Met Gly Lys Glu Asn Met Glu Gln Pro Asn Asn
                 470                 475                 480

 Val Pro Val Lys Arg Phe Gln Leu Cys Lys Glu Leu Ser Glu Leu
                 485                 490                 495

 Val Ser Ile Cys Lys Ser Val Gln Phe Lys Glu Phe Gln Met Ser
                 500                 505                 510

 Phe Gln Val Gln Lys Tyr Trp Glu Val Cys Ser Phe Asn Glu Val
                 515                 520                 525

 Leu Ala Ser Lys Tyr Ala Asn Glu Asn Pro Gly Asp Phe Val Asn
                 530                 535                 540

 Tyr Asn Lys Arg Phe Leu Ala Arg Val Phe Pro Ser Pro Met Arg
                 545                 550                 555

 Ile Asp Ser Ser Asn Met Asn Pro Gln Asp Phe Trp Lys Cys Gly
                 560                 565                 570

 Cys Gln Ile Val Ala Met Asn Phe Gln Thr Pro Gly Leu Met Met
                 575                 580                 585

 Asp Leu Asn Ile Gly Trp Phe Arg Gln Asn Gly Asn Cys Gly Tyr
                 590                 595                 600

 Val Leu Arg Pro Ala Ile Met Arg Glu Glu Val Ser Phe Phe Ser
                 605                 610                 615

 Val Asn Thr Lys Asp Ser Val Pro Gly Val Ser Pro Gln Leu Leu
                 620                 625                 630

 His Ile Lys Ile Ile Ser Gly Gln Asn Phe Pro Lys Pro Lys Gly
                 635                 640                 645

 Ser Gly Ala Lys Gly Asp Val Val Asp Pro Tyr Val Tyr Val Glu
                 650                 655                 660

 Ile His Gly Ile Pro Ala Asp Cys Ala Glu Gln Arg Thr Lys Thr
                 665                 670                 675

 Val His Gln Asn Gly Asp Ala His Ile Phe Asp Glu Ser Phe Glu
                 680                 685                 690

 Phe Gln Ile Asn Leu Pro Glu Leu Ala Met Val Arg Phe Val Val
                 695                 700                 705

 Leu Asp Asp Asp Tyr Ile Gly Asp Glu Phe Ile Gly Gln Tyr Thr
                 710                 715                 720

 Ile Pro Phe Glu Cys Leu Gln Thr Gly Tyr Arg His Val Pro Leu
                 725                 730                 735

 Gln Ser Leu Thr Gly Glu Val Leu Ala His Ala Ser Leu Phe Val
                 740                 745                 750

 His Val Ala Ile Thr Asn Arg Arg Gly Gly Gly Lys Pro Arg Lys
                 755                 760                 765

 Arg Gly Leu Ser Val Arg Lys Gly Lys Lys Ser Arg Glu Tyr Ala
                 770                 775                 780

 Ser Leu Arg Thr Leu Trp Ile Lys Thr Val Asp Glu Val Phe Lys
                 785                 790                 795

 Asn Ala Gln Pro Pro Ile Arg Asp Ala Thr Asp Leu Arg Glu Asn
                 800                 805                 810

 Met Gln Asn Ala Val Val Ser Phe Lys Glu Leu Cys Gly Leu Ser
                 815                 820                 825

 Ser Val Ala Asn Leu Met Gln Cys Met Leu Ala Val Ser Pro Arg
                 830                 835                 840

 Phe Leu Gly Pro Asp Asn Thr Pro Leu Val Val Leu Asn Leu Ser
                 845                 850                 855

 Glu Gln Tyr Pro Thr Met Glu Leu Gln Gly Ile Val Pro Glu Val
                 860                 865                 870

 Leu Lys Lys Ile Val Thr Thr Tyr Asp Met Met Ile Gln Ser Leu
                 875                 880                 885

 Lys Ala Leu Ile Glu Asn Ala Asp Ala Val Tyr Glu Lys Ile Val
                 890                 895                 900

 His Cys Gln Lys Ala Ala Met Glu Phe His Glu His Leu His Ser
                 905                 910                 915

 Ile Gly Thr Lys Glu Gly Leu Lys Glu Arg Lys Leu Gln Lys Ala
                 920                 925                 930

 Val Glu Ser Phe Thr Trp Asn Ile Thr Ile Leu Lys Gly Gln Ala
                 935                 940                 945

 Asp Leu Leu Lys Tyr Ala Lys Asn Glu Thr Leu Glu Asn Leu Lys
                 950                 955                 960

 Gln Ile His Phe Ala Ala Val Ser Cys Gly Leu Asn Lys Pro Gly
                 965                 970                 975

 Thr Glu Asn Ala Asp Val Gln Lys Pro Arg Arg Ser Leu Glu Val
                 980                 985                 990

 Ile Pro Glu Lys Ala Asn Asp Glu Thr Gly Glu
                 995                1000

<210> 2984
<211> 3326
<212> DNA
<213> Homo sapien

<400> 2984
 ggccagtccg cccggcggct cgcgcacggc tccgcggtcc cttttgcctg 50

 tccagccggc cgcctgtccc tgctccctcc ctccgtgagg tgtccgggtt 100

 cccttcgccc agctctccca cccctacccg accccggcgc ccgggctccc 150

 agagggaact gcacttcggc agagttgaat gaatgaagag agacgcggag 200

 aactcctaag gaggagattg gacaggctgg actccccatt gcttttctaa 250

 aaatcttgga aactttgtcc ttcattgaat tacgacactg tccaccttta 300

 atttcctcga aaacgcctgt aactcggctg aagccatgcc ttgtgttcag 350

 gcgcagtatg ggtcctcgcc tcaaggagcc agccccgctt ctcagagcta 400

 cagttaccac tcttcgggag aatacagctc cgatttctta actccagagt 450

 ttgtcaagtt tagcatggac ctcaccaaca ctgaaatcac tgccaccact 500

 tctctcccca gcttcagtac ctttatggac aactacagca caggctacga 550

 cgtcaagcca ccttgcttgt accaaatgcc cctgtccgga cagcagtcct 600

 ccattaaggt agaagacatt cagatgcaca actaccagca acacagccac 650

 ctgccccccc agtctgagga gatgatgccg cactccgggt cggtttacta 700

 caagccctcc tcgcccccga cgcccaccac cccgggcttc caggtgcagc 750

 acagccccat gtgggacgac ccgggatctc tccacaactt ccaccagaac 800

 tacgtggcca ctacgcacat gatcgagcag aggaaaacgc cagtctcccg 850

 cctctccctc ttctccttta agcaatcgcc ccctggcacc ccggtgtcta 900

 gttgccagat gcgcttcgac gggcccctgc acgtccccat gaacccggag 950

 cccgccggca gccaccacgt ggtggacggg cagaccttcg ctgtgcccaa 1000

 ccccattcgc aagcccgcgt ccatgggctt cccgggcctg cagatcggcc 1050

 acgcgtctca gctgctcgac acgcaggtgc cctcaccgcc gtcgcggggc 1100

 tccccctcca acgaggggct gtgcgctgtg tgtggggaca acgcggcctg 1150

 ccaacactac ggcgtgcgca cctgtgaggg ctgcaaaggc ttctttaagc 1200

 gcacagtgca aaaaaatgca aaatacgtgt gtttagcaaa taaaaactgc 1250

 ccagtggaca agcgtcgccg gaatcgctgt cagtactgcc gatttcagaa 1300

 gtgcctggct gttgggatgg tcaaagaagt ggttcgcaca gacagtttaa 1350

 aaggccggag aggtcgtttg ccctcgaaac cgaagagccc acaggagccc 1400

 tctccccctt cgcccccggt gagtctgatc agtgccctcg tcagggccca 1450

 tgtcgactcc aacccggcta tgaccagcct ggactattcc aggttccagg 1500

 cgaaccctga ctatcaaatg agtggagatg acacccagca tatccagcaa 1550

 ttctatgatc tcctgactgg ctccatggag atcatccggg gctgggcaga 1600

 gaagatccct ggcttcgcag acctgcccaa agccgaccaa gacctgcttt 1650

 ttgaatcagc tttcttagaa ctgtttgtcc ttcgattagc atacagaata 1700

 tgaacatcga catttctgcc ttctcctgca ttgctgccct ggctatggtc 1750

 acagagagac acgggctcaa ggaacccaag agagtggaag aactgcaaaa 1800

 caagattgta aattgtctca aagaccacgt gactttcaac aatggggggt 1850

 tgaaccgccc caattatttg tccaaactgt tggggaagct cccagaactt 1900

 cgtacccttt gcacacaggg gctacagcgc attttctacc tgaaattgga 1950

 agacttggtg ccaccgccag caataattga caaacttttc ctggacactt 2000

 tacctttcta agacctcctc ccaagcactt caaaggaact ggaatgataa 2050

 tggaaactgt caagaggggg caagtcacat gggcagagat agccgtgtga 2100

 gcagtctcag ctcaagctgc cccccatttc tgtaaccctc ctagccccct 2150

 tgatccctaa agaaaacaaa caaacaaaca aaaactgttg ctatttccta 2200

 acctgcaggc agaacctgaa agggcatttt ggctccgggg catcctggat 2250

 ttagaacatg gactacacac aatacagtgg tataaacttt ttattctcag 2300

 tttaaaaatc agtttgttgt tcagaagaaa gattgctata atgtataatg 2350

 ggaaatgttt ggccatgctt ggttgttgca gttcagacaa atgtaacaca 2400

 cacacacata cacacacaca cacacacaca gagacacatc ttaaggggac 2450

 ccacaagtat tgccctttaa caagacttca aagttttctg ctgtaaagaa 2500

 agctgtaata tatagtaaaa ctaaatgttg cgtgggtggc atgagttgaa 2550

 gaaggcaaag gcttgtaaat ttacccaatg cagtttggct ttttaaatta 2600

 ttttgtgcct atttatgaat aaatattaca aattctaaaa gataagtgtg 2650

 tttgcaaaaa aaaagaaaat aaatacataa aaaagggaca agcatgttga 2700

 ttctaggttg aaaatgttat aggcacttgc tacttcagta atgtctatat 2750

 tatataaata gtatttcaga cactatgtag tctgttagat tttataaaga 2800

 ttggtagtta tctgagctta aacattttct caattgtaaa ataggtgggc 2850

 acaagtatta cacatcagaa aatcctgaca aaagggacac atagtgtttg 2900

 taacaccgtc caacattcct tgtttgtaag tgttgtatgt accgttgatg 2950

 ttgataaaaa gaaagtttat atcttgatta ttttgttgtc taaagctaaa 3000

 caaaacttgc atgcagcagc ttttgactgt ttccagagtg cttataatat 3050

 acataactcc ctggaaataa ctgagcactt tgaatttttt ttatgtctaa 3100

 aattgtcagt taatttatta ttttgtttga gtaagaattt taatattgcc 3150

 atattctgta gtatttttct ttgtatattt ctagtatggc acatgatatg 3200

 agtcactgcc tttttttcta tggtgtatga cagttagaga tgctgatttt 3250

 ttttctgata aattctttct ttgagaaaga caattttaat gtttacaaca 3300

 ataaaccatg taaatgaaaa aaaaaa 3326

<210> 2985
<211> 455
<212> PRT
<213> Homo sapien

<400> 2985
 Met Pro Cys Val Gln Ala Gln Tyr Gly Ser Ser Pro Gln Gly Ala
   1               5                  10                  15

 Ser Pro Ala Ser Gln Ser Tyr Ser Tyr His Ser Ser Gly Glu Tyr
                  20                  25                  30

 Ser Ser Asp Phe Leu Thr Pro Glu Phe Val Lys Phe Ser Met Asp
                  35                  40                  45

 Leu Thr Asn Thr Glu Ile Thr Ala Thr Thr Ser Leu Pro Ser Phe
                  50                  55                  60

 Ser Thr Phe Met Asp Asn Tyr Ser Thr Gly Tyr Asp Val Lys Pro
                  65                  70                  75

 Pro Cys Leu Tyr Gln Met Pro Leu Ser Gly Gln Gln Ser Ser Ile
                  80                  85                  90

 Lys Val Glu Asp Ile Gln Met His Asn Tyr Gln Gln His Ser His
                  95                 100                 105

 Leu Pro Pro Gln Ser Glu Glu Met Met Pro His Ser Gly Ser Val
                 110                 115                 120

 Tyr Tyr Lys Pro Ser Ser Pro Pro Thr Pro Thr Thr Pro Gly Phe
                 125                 130                 135

 Gln Val Gln His Ser Pro Met Trp Asp Asp Pro Gly Ser Leu His
                 140                 145                 150

 Asn Phe His Gln Asn Tyr Val Ala Thr Thr His Met Ile Glu Gln
                 155                 160                 165

 Arg Lys Thr Pro Val Ser Arg Leu Ser Leu Phe Ser Phe Lys Gln
                 170                 175                 180

 Ser Pro Pro Gly Thr Pro Val Ser Ser Cys Gln Met Arg Phe Asp
                 185                 190                 195

 Gly Pro Leu His Val Pro Met Asn Pro Glu Pro Ala Gly Ser His
                 200                 205                 210

 His Val Val Asp Gly Gln Thr Phe Ala Val Pro Asn Pro Ile Arg
                 215                 220                 225

 Lys Pro Ala Ser Met Gly Phe Pro Gly Leu Gln Ile Gly His Ala
                 230                 235                 240

 Ser Gln Leu Leu Asp Thr Gln Val Pro Ser Pro Pro Ser Arg Gly
                 245                 250                 255

 Ser Pro Ser Asn Glu Gly Leu Cys Ala Val Cys Gly Asp Asn Ala
                 260                 265                 270

 Ala Cys Gln His Tyr Gly Val Arg Thr Cys Glu Gly Cys Lys Gly
                 275                 280                 285

 Phe Phe Lys Arg Thr Val Gln Lys Asn Ala Lys Tyr Val Cys Leu
                 290                 295                 300

 Ala Asn Lys Asn Cys Pro Val Asp Lys Arg Arg Arg Asn Arg Cys
                 305                 310                 315

 Gln Tyr Cys Arg Phe Gln Lys Cys Leu Ala Val Gly Met Val Lys
                 320                 325                 330

 Glu Val Val Arg Thr Asp Ser Leu Lys Gly Arg Arg Gly Arg Leu
                 335                 340                 345

 Pro Ser Lys Pro Lys Ser Pro Gln Glu Pro Ser Pro Pro Ser Pro
                 350                 355                 360

 Pro Val Ser Leu Ile Ser Ala Leu Val Arg Ala His Val Asp Ser
                 365                 370                 375

 Asn Pro Ala Met Thr Ser Leu Asp Tyr Ser Arg Phe Gln Ala Asn
                 380                 385                 390

 Pro Asp Tyr Gln Met Ser Gly Asp Asp Thr Gln His Ile Gln Gln
                 395                 400                 405

 Phe Tyr Asp Leu Leu Thr Gly Ser Met Glu Ile Ile Arg Gly Trp
                 410                 415                 420

 Ala Glu Lys Ile Pro Gly Phe Ala Asp Leu Pro Lys Ala Asp Gln
                 425                 430                 435

 Asp Leu Leu Phe Glu Ser Ala Phe Leu Glu Leu Phe Val Leu Arg
                 440                 445                 450

 Leu Ala Tyr Arg Ile
                 455

<210> 2986
<211> 3321
<212> DNA
<213> Homo sapien

<400> 2986
 atggaggccg agcggggtcc cgagcgccgg cctgcggagc gtagcagccc 50

 gggccagacg ccggaggagg gcgcgcaggc cttggccgag ttcgcggcgc 100

 tgcacggccc ggcgctgcgc gcttcggggg tccccgaacg ttactggggc 150

 cgcctcctgc acaagctgga gcacgaggtt ttcgacgctg gggaagtgtt 200

 tgggatcatg caagtggagg aggtagaaga ggaggaggac gaggcagccc 250

 gggaggtgcg gaagcagcag cccaacccgg ggaacgagct gtgctacaag 300

 gtcatcgtga ccagggagag cgggctccag gcagcccacc ccaacagcat 350

 cttcctcatc gaccacgcct ggacgtgccg tgtggagcac gcgcgccagc 400

 agctgcagca ggtgcccggg ctgctgcacc gcatggccaa cctgatgggc 450

 attgagttcc acggtgagct gcccagtaca gaggctgtgg ccctggtgct 500

 ggaggagatg tggaagttca accagaccta ccagctggcc catgggacag 550

 ctgaggagaa gatgccggtg tggtatatca tggacgagtt cggttcgcgg 600

 atccagcacg cggacgtgcc cagcttcgcc acggcaccct tcttctacat 650

 gccgcagcag gtggcctaca cgctgctgtg gcccctgagg gacctggaca 700

 ctggcgagga ggtgacccga gactttgcct acggagagac ggaccccctg 750

 atccggaagt gcatgctgct gccctgggcc cccaccgaca tgctggacct 800

 cagctcttgc acacccgagc cgcccgccga gcactaccag gccattctgg 850

 aggaaaacaa ggagaagctg ccacttgaca tcaaccccgt ggtgcacccc 900

 cacggccaca tcttcaaggt ctacacggac gtgcagcagg tggccagcag 950

 cctcacccac ccgcgcttca ccctcaccca gagtgaggcg gacgccgaca 1000

 tcctcttcaa cttctcacac ttcaaggact acaggaaact cagccaggag 1050

 aggccaggcg tgctgctgaa ccagttcccc tgcgagaacc tgctgactgt 1100

 caaggactgc ctggcctcca tcgcgcgccg ggcaggtggc cccgagggcc 1150

 caccctggct gccccgaacc ttcaacctgc gcactgagct gccccagttt 1200

 gtcagctact tccagcagcg ggaaaggtgg ggcgaggaca accactggat 1250

 ctgcaagccc tggaacctgg cgcgcagcct ggacacccac gtcaccaaga 1300

 gcctgcacag catcatccgg caccgagaga gcacccccaa ggttgtgtcc 1350

 aagtacatcg aaagtcccgt gttgttcctt cgagaagacg tgggaaaggt 1400

 caagttcgac atccgctaca tcgtgctgct gcggtcagtg aggcccctac 1450

 ggttgttcgt gtatgatgtg ttctggctgc ggttctccaa ccgggccttt 1500

 gcactcaacg acctggatga ctacgagaag cacttcacgg tcatgaacta 1550

 tgacccggat gtggtgctga agcaggtgca ctgtgaagag ttcatccccg 1600

 agtttgagaa gcaataccca gaatttccct ggacggacgt ccaggctgag 1650

 atcttccggg ccttcacgga gctgttccag gtggcctgtg ccaagccacc 1700

 acccctgggc ctctgcgact acccctcatc ccgggccatg tatgccgtcg 1750

 acctcatgct gaagtgggac aacggcccag atggaaggcg ggtgatgcag 1800

 ccgcagatcc tggaggtgaa cttcaacccc gactgtgagc gagcctgcag 1850

 gtaccacccc accttcttca acgacgtctt cagcaccttg tttctggacc 1900

 agcccggtgg ctgccacgtt acctgccttg tctaggcact cgctgtcccc 1950

 aaaacctgtg cttggggcag gattccaacc tcagttctct gagctgcttc 2000

 tgcaaaggcc cccatgtccc tccccacacc ggccctgggc atagcctcag 2050

 ccccaggcct ctgtcctgcc gagccatcct cccggcgcca cactccggga 2100

 gcacagcatc ctcctctcac ctgtgggtca gagcaggaca gtgatggtgt 2150

 ccccagggct gagcaccacc ccacgccctg ccctcacccc tcaccaccat 2200

 ctgtgcactg atgagtctcc agtttagcca agggctttgt tcctggcatg 2250

 gagaatttgt tcctggctgc tgtgtttcca gggggtgctg ggggaagggt 2300

 tccgtggagc gagacaaggt gtcctcggga gcagggttcc accgggaagc 2350

 gtttgggagc cctgtatcac acggggcagg cgggtttctc ttccggggtc 2400

 tctgctctta tgcatcagga cgaccccggg acggctgtgg ggccccacac 2450

 tgcacccaca gggctctatg cgacaggggc ccaggaacag cctgaggcca 2500

 ccacccagca agcccgcctt atcacccatt ccagctcacc cagaaccttc 2550

 accagcaaac ctcctgctga ggtcctggca ggaggccacc gtcttgttac 2600

 cgtttccttt tcgtttgctg agggtcacag accccaacag ggaaatcagt 2650

 atctgtcttc ccagtggttg ccctgctcgc cgggcactcc acggggtccc 2700

 gcccttgtgt gagatgggcc aggatccttc ggcaaggggc gcctggggct 2750

 ggggctgatt gtgggcggtg gagcgccaga cagaaaagga ttccaatgag 2800

 aacttcaggt taaagtcaga tgccacctac cagggtctac agtcaaaatg 2850

 ttggcttttt cttatttttt aatgtatggg agaaaaatgt aaaattccag 2900

 ttcttttcta attgtgtttc tgaaattagg agtcagctgc cagcgttttt 2950

 gtgtggctgc agtgtgcctg ggcccagctc acgggcagtg ggtggaccta 3000

 actgcccagg caggcgagag ctacttccag agccttccag tgcatgggag 3050

 ggcagggcta ggtgtagcgg tgtctcctct ttgaaattaa gaactatctt 3100

 tcttgtagca aagctgcacc tgatgatgct gcctctcctc tctgtgttgt 3150

 ctgggccctt gtttacaagc acgcgttacc cttcctgagg ggagccatgc 3200

 tctagcccct ggagggcctg ttgcaggggc agggcgggcc cgtcgccttt 3250

 ggcagctcct ggagagctgt ggacatgcag tccccctcag ttcgtgctgc 3300

 aataaaggcc atcttctctt a 3321

<210> 2987
<211> 644
<212> PRT
<213> Homo sapien

<400> 2987
 Met Glu Ala Glu Arg Gly Pro Glu Arg Arg Pro Ala Glu Arg Ser
   1               5                  10                  15

 Ser Pro Gly Gln Thr Pro Glu Glu Gly Ala Gln Ala Leu Ala Glu
                  20                  25                  30

 Phe Ala Ala Leu His Gly Pro Ala Leu Arg Ala Ser Gly Val Pro
                  35                  40                  45

 Glu Arg Tyr Trp Gly Arg Leu Leu His Lys Leu Glu His Glu Val
                  50                  55                  60

 Phe Asp Ala Gly Glu Val Phe Gly Ile Met Gln Val Glu Glu Val
                  65                  70                  75

 Glu Glu Glu Glu Asp Glu Ala Ala Arg Glu Val Arg Lys Gln Gln
                  80                  85                  90

 Pro Asn Pro Gly Asn Glu Leu Cys Tyr Lys Val Ile Val Thr Arg
                  95                 100                 105

 Glu Ser Gly Leu Gln Ala Ala His Pro Asn Ser Ile Phe Leu Ile
                 110                 115                 120

 Asp His Ala Trp Thr Cys Arg Val Glu His Ala Arg Gln Gln Leu
                 125                 130                 135

 Gln Gln Val Pro Gly Leu Leu His Arg Met Ala Asn Leu Met Gly
                 140                 145                 150

 Ile Glu Phe His Gly Glu Leu Pro Ser Thr Glu Ala Val Ala Leu
                 155                 160                 165

 Val Leu Glu Glu Met Trp Lys Phe Asn Gln Thr Tyr Gln Leu Ala
                 170                 175                 180

 His Gly Thr Ala Glu Glu Lys Met Pro Val Trp Tyr Ile Met Asp
                 185                 190                 195

 Glu Phe Gly Ser Arg Ile Gln His Ala Asp Val Pro Ser Phe Ala
                 200                 205                 210

 Thr Ala Pro Phe Phe Tyr Met Pro Gln Gln Val Ala Tyr Thr Leu
                 215                 220                 225

 Leu Trp Pro Leu Arg Asp Leu Asp Thr Gly Glu Glu Val Thr Arg
                 230                 235                 240

 Asp Phe Ala Tyr Gly Glu Thr Asp Pro Leu Ile Arg Lys Cys Met
                 245                 250                 255

 Leu Leu Pro Trp Ala Pro Thr Asp Met Leu Asp Leu Ser Ser Cys
                 260                 265                 270

 Thr Pro Glu Pro Pro Ala Glu His Tyr Gln Ala Ile Leu Glu Glu
                 275                 280                 285

 Asn Lys Glu Lys Leu Pro Leu Asp Ile Asn Pro Val Val His Pro
                 290                 295                 300

 His Gly His Ile Phe Lys Val Tyr Thr Asp Val Gln Gln Val Ala
                 305                 310                 315

 Ser Ser Leu Thr His Pro Arg Phe Thr Leu Thr Gln Ser Glu Ala
                 320                 325                 330

 Asp Ala Asp Ile Leu Phe Asn Phe Ser His Phe Lys Asp Tyr Arg
                 335                 340                 345

 Lys Leu Ser Gln Glu Arg Pro Gly Val Leu Leu Asn Gln Phe Pro
                 350                 355                 360

 Cys Glu Asn Leu Leu Thr Val Lys Asp Cys Leu Ala Ser Ile Ala
                 365                 370                 375

 Arg Arg Ala Gly Gly Pro Glu Gly Pro Pro Trp Leu Pro Arg Thr
                 380                 385                 390

 Phe Asn Leu Arg Thr Glu Leu Pro Gln Phe Val Ser Tyr Phe Gln
                 395                 400                 405

 Gln Arg Glu Arg Trp Gly Glu Asp Asn His Trp Ile Cys Lys Pro
                 410                 415                 420

 Trp Asn Leu Ala Arg Ser Leu Asp Thr His Val Thr Lys Ser Leu
                 425                 430                 435

 His Ser Ile Ile Arg His Arg Glu Ser Thr Pro Lys Val Val Ser
                 440                 445                 450

 Lys Tyr Ile Glu Ser Pro Val Leu Phe Leu Arg Glu Asp Val Gly
                 455                 460                 465

 Lys Val Lys Phe Asp Ile Arg Tyr Ile Val Leu Leu Arg Ser Val
                 470                 475                 480

 Arg Pro Leu Arg Leu Phe Val Tyr Asp Val Phe Trp Leu Arg Phe
                 485                 490                 495

 Ser Asn Arg Ala Phe Ala Leu Asn Asp Leu Asp Asp Tyr Glu Lys
                 500                 505                 510

 His Phe Thr Val Met Asn Tyr Asp Pro Asp Val Val Leu Lys Gln
                 515                 520                 525

 Val His Cys Glu Glu Phe Ile Pro Glu Phe Glu Lys Gln Tyr Pro
                 530                 535                 540

 Glu Phe Pro Trp Thr Asp Val Gln Ala Glu Ile Phe Arg Ala Phe
                 545                 550                 555

 Thr Glu Leu Phe Gln Val Ala Cys Ala Lys Pro Pro Pro Leu Gly
                 560                 565                 570

 Leu Cys Asp Tyr Pro Ser Ser Arg Ala Met Tyr Ala Val Asp Leu
                 575                 580                 585

 Met Leu Lys Trp Asp Asn Gly Pro Asp Gly Arg Arg Val Met Gln
                 590                 595                 600

 Pro Gln Ile Leu Glu Val Asn Phe Asn Pro Asp Cys Glu Arg Ala
                 605                 610                 615

 Cys Arg Tyr His Pro Thr Phe Phe Asn Asp Val Phe Ser Thr Leu
                 620                 625                 630

 Phe Leu Asp Gln Pro Gly Gly Cys His Val Thr Cys Leu Val
                 635                 640

<210> 2988
<211> 2646
<212> DNA
<213> Homo sapien

<400> 2988
 cctacccgcg cgcaggccaa gttgctgaat caatggagcc ctccccaacc 50

 cgggcgttcc ccagcgaggc ttccttccca tcctcctgac caccggggct 100

 tttcgtgagc tcgtctctga tctcgcgcaa gagtgacaca caggtgttca 150

 aagacgcttc tggggagtga gggaagcggt ttacgagtga cttggctgga 200

 gcctcagggg cgggcactgg cacggaacac accctgaggc cagccctggc 250

 tgcccaggcg gagctgcctc ttctcccgcg ggttggtgga cccgctcagt 300

 acggagttgg ggaagctctt tcacttcgga ggattgctca acaaccatgc 350

 tgggcatctg gaccctccta cctctggttc ttacgtctgt tgctagatta 400

 tcgtccaaaa gtgttaatgc ccaagtgact gacatcaact ccaagggatt 450

 ggaattgagg aagactgtta ctacagttga gactcagaac ttggaaggcc 500

 tgcatcatga tggccaattc tgccataagc cctgtcctcc aggtgaaagg 550

 aaagctaggg actgcacagt caatggggat gaaccagact gcgtgccctg 600

 ccaagaaggg aaggagtaca cagacaaagc ccatttttct tccaaatgca 650

 gaagatgtag attgtgtgat gaaggacatg atgtgaacat ggaatcatca 700

 aggaatgcac actcaccagc aacaccaagt gcaaagagga aggatccaga 750

 tctaacttgg ggtggctttg tcttcttctt ttgccaattc cactaattgt 800

 ttgggtgaag agaaaggaag tacagaaaac atgcagaaag cacagaaagg 850

 aaaaccaagg ttctcatgaa tctccaacct taaatcctga aacagtggca 900

 ataaatttat ctgatgttga cttgagtaaa tatatcacca ctattgctgg 950

 agtcatgaca ctaagtcaag ttaaaggctt tgttcgaaag aatggtgtca 1000

 atgaagccaa aatagatgag atcaagaatg acaatgtcca agacacagca 1050

 gaacagaaag ttcaactgct tcgtaattgg catcaacttc atggaaagaa 1100

 agaagcgtat gacacattga ttaaagatct caaaaaagcc aatctttgta 1150

 ctcttgcaga gaaaattcag actatcatcc tcaaggacat tactagtgac 1200

 tcagaaaatt caaacttcag aaatgaaatc caaagcttgg tctagagtga 1250

 aaaacaacaa attcagttct gagtatatgc aattagtgtt tgaaaagatt 1300

 cttaatagct ggctgtaaat actgcttggt tttttactgg gtacatttta 1350

 tcatttatta gcgctgaaga gccaacatat ttgtagattt ttaatatctc 1400

 atgattctgc ctccaaggat gtttaaaatc tagttgggaa aacaaacttc 1450

 atcaagagta aatgcagtgg catgctaagt acccaaatag gagtgtatgc 1500

 agaggatgaa agattaagat tatgctctgg catctaacat atgattctgt 1550

 agtatgaatg taatcagtgt atgttagtac aaatgtctat ccacaggcta 1600

 accccactct atgaatcaat agaagaagct atgacctttt gctgaaatat 1650

 cagttactga acaggcaggc cactttgcct ctaaattacc tctgataatt 1700

 ctagagattt taccatattt ctaaactttg tttataactc tgagaagatc 1750

 atatttatgt aaagtatatg tatttgagtg cagaatttaa ataaggctct 1800

 acctcaaaga cctttgcaca gtttattggt gtcatattat acaatatttc 1850

 aattgtgaat tcacatagaa aacattaaat tataatgttt gactattata 1900

 tatgtgtatg cattttactg gctcaaaact acctacttct ttctcaggca 1950

 tcaaaagcat tttgagcagg agagtattac tagagctttg ccacctctcc 2000

 atttttgcct tggtgctcat cttaatggcc taatgcaccc ccaaacatgg 2050

 aaatatcacc aaaaaatact taatagtcca ccaaaaggca agactgccct 2100

 tagaaattct agcctggttt ggagatacta actgctctca gagaaagtag 2150

 ctttgtgaca tgtcatgaac ccatgtttgc aatcaaagat gataaaatag 2200

 attcttattt ttcccccacc cccgaaaatg ttcaataatg tcccatgtaa 2250

 aacctgctac aaatggcagc ttatacatag caatggtaaa atcatcatct 2300

 ggatttagga attgctcttg tcataccccc aagtttctaa gatttaagat 2350

 tctccttact actatcctac gtttaaatat ctttgaaagt ttgtattaaa 2400

 tgtgaatttt aagaaataat atttatattt ctgtaaatgt aaactgtgaa 2450

 gatagttata aactgaagca gatacctgga accacctaaa gaacttccat 2500

 ttatggagga tttttttgcc ccttgtgttt ggaattataa aatataggta 2550

 aaagtacgta attaaataat gtttttggta aaaaaaaaaa aaaaaaaaaa 2600

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 2646

<210> 2989
<211> 149
<212> PRT
<213> Homo sapien

<400> 2989
 Met Leu Gly Ile Trp Thr Leu Leu Pro Leu Val Leu Thr Ser Val
   1               5                  10                  15

 Ala Arg Leu Ser Ser Lys Ser Val Asn Ala Gln Val Thr Asp Ile
                  20                  25                  30

 Asn Ser Lys Gly Leu Glu Leu Arg Lys Thr Val Thr Thr Val Glu
                  35                  40                  45

 Thr Gln Asn Leu Glu Gly Leu His His Asp Gly Gln Phe Cys His
                  50                  55                  60

 Lys Pro Cys Pro Pro Gly Glu Arg Lys Ala Arg Asp Cys Thr Val
                  65                  70                  75

 Asn Gly Asp Glu Pro Asp Cys Val Pro Cys Gln Glu Gly Lys Glu
                  80                  85                  90

 Tyr Thr Asp Lys Ala His Phe Ser Ser Lys Cys Arg Arg Cys Arg
                  95                 100                 105

 Leu Cys Asp Glu Gly His Asp Val Asn Met Glu Ser Ser Arg Asn
                 110                 115                 120

 Ala His Ser Pro Ala Thr Pro Ser Ala Lys Arg Lys Asp Pro Asp
                 125                 130                 135

 Leu Thr Trp Gly Gly Phe Val Phe Phe Phe Cys Gln Phe His
                 140                 145

<210> 2990
<211> 7869
<212> DNA
<213> Homo sapien

<400> 2990
 ggcacgaggt ttggggcatc tccgcggtcc ggcccggggc cccgggatct 50

 cggctgtcct tcctcccggc ataagatgca catttttctg ctctggagcc 100

 gggaatgaaa tattcttgag ttcttacaac tttatgacga gacccatgtg 150

 tggtgctatt gagaaattca ttgggaagtt ggaagacatt tcaaacaaca 200

 ggttgttttg gtttctatag tacaattggg gtggcattct gttttgtgaa 250

 aggaggaagg acttaggcca gaaaactcat atgctatggt taactggttc 300

 ccagcctccg agaatcttgt tttccatggt gtaaaactta ctcagcatca 350

 ggataaggga taacgactct atggatatac agaatccttc accatggtaa 400

 aactcgcaaa cccgctttat actgagtgga ttttggaggc catcaaaaaa 450

 gtgaaaaagc agaaacagcg tccttcagaa gaaaggatat gcaatgctgt 500

 gtcttcatcc catggcttgg atcgtaaaac tgttttagaa caattggagt 550

 tgagtgttaa agatggaaca attttaaaag tctcaaataa aggactcaat 600

 tcctataaag atcctgataa tcctgggcga atagcacttc ctaagcctcg 650

 gaaccatgga aaattggata ataaacaaaa tgtggattgg aataaactga 700

 taaagcgggc agttgagggc ttggcagagt ctggtggctc aactttgaaa 750

 agcattgaac gttttttgaa aggtcagaag gatgtgtctg cattattcgg 800

 aggcagtgct gcctctggct ttcaccagca gttacgattg gctatcaaac 850

 gtgccattgg ccacggcaga ctccttaaag atggacctct ttatcggctc 900

 aacactaaag caaccaacgt ggatgggaaa gagagttgtg agtctctttc 950

 ctgtttacct ccagtgtccc ttcttccaca tgaaaaggat aagccggttg 1000

 ctgaaccaat ccccatctgt agtttctgtc ttggtacaaa agaacaaaac 1050

 cgagaaaaga agccagagga actcatctcc tgtgccgact gtggcaacag 1100

 tggccatcca tcctgtttaa agttttcccc tgaactaacg gttcgagtga 1150

 aggccttacg gtggcagtgc atcgagtgta aaacatgcag ctcctgtcga 1200

 gatcaaggca aaaatgcgga taacatgctc ttttgtgatt catgtgaccg 1250

 aggttttcac atggagtgtt gtgatccgcc actcacccgt atgccaaaag 1300

 gcatgtggat atgtcaaata tgtcgaccta ggaaaaaagg acgaaaactt 1350

 ctacaaaaga aggcagcaca gataaaacgg cgctatacta atccaatagg 1400

 acgtccaaaa aacaggttaa agaaacaaaa cacggtatca aaaggtccct 1450

 tcagcaaagt tcgaactggc cctggaaggg gtaggaaacg aaaaatcact 1500

 ctttccagcc aatcagcatc atcatcatca gaagaaggat atttagagcg 1550

 gatagatggc ttggacttct gcagagatag caatgtctcc ttgaggttca 1600

 acaagaaaac caaagggctc attgatggcc ttaccaaatt ttttacccct 1650

 tcccctgatg ggcggaaagc tcggggggaa gtggtggact actctgagca 1700

 atatcgaatc agaaagaggg gcaacaggaa atcaagcact tcagattggc 1750

 ccacagacaa tcaggatggc tgggatggca aacaagaaaa tgaggagcga 1800

 ctttttggga gccaggaaat catgactgag aaagatatgg aattatttcg 1850

 tgatatccaa gaacaagcac tgcagaaagt tggagtgact ggtccccctg 1900

 atccacaagt ccgctgtccc tctgtcattg agtttgggaa gtatgaaatt 1950

 cacacctggt actcctcccc atatcctcaa gaatactcaa ggctgcccaa 2000

 attgtatctt tgtgaatttt gtctaaaata tatgaaaagt agaactattc 2050

 tgcagcagca catgaagaaa tgtggttggt tccatcctcc tgccaatgag 2100

 atttacagaa agaataatat ttctgtcttt gaggttgatg ggaatgtgag 2150

 taccatttat tgtcaaaacc tgtgtctttt ggcaaagttg tttcttgacc 2200

 acaaaaccct ctattacgat gtggagccat ttctttttta tgtactaaca 2250

 cagaatgatg tcaagggctg ccaccttgtt ggctactttt ctaaggaaaa 2300

 gcactgccaa cagaagtaca atgtttcctg tataatgatt cttcctcaat 2350

 accagcgtaa gggctatggc aggtttctca tcgatttcag ttatttgtta 2400

 tcaaagcgtg aaggccaagc agggtctcca gagaaaccgt tatctgatct 2450

 gggtcgtctt tcctacatgg catattggaa aagtgtaata ttggagtgcc 2500

 tttatcacca aaatgacaag cagatcagca ttaagaagtt aagcaagttg 2550

 actggaatct gccctcaaga catcacttcc acactccacc acctacgaat 2600

 gctggacttc cgtagtgacc aatttgtgat tatccgccgg gaaaaactta 2650

 tccaggatca catggcaaag cttcagctga atttgcgacc tgtagatgta 2700

 gatccagaat gtttgcgctg gactccagtc atagtgtcca actctgtggt 2750

 ctcagaggag gaagaagagg aggctgagga aggagaaaac gaagagccac 2800

 agtgccagga aagagaatta gagatcagtg tgggaaagtc tgtgtctcat 2850

 gagaacaaag aacaagattc ttattcagta gaaagtgaaa agaaaccaga 2900

 agttatggct ccagtcagtt ctacacgttt gagcaaacaa gtccttcctc 2950

 atgatagtct tcctgcaaat agccagccat ctcggagggg ccgctggggg 3000

 aggaagaaca gaaaaaccca ggaacgtttt ggtgataaag attctaaact 3050

 gctcttggaa gagacgtctt cagctcctca ggaacaatat ggagaatgtg 3100

 gggagaaatc agaagccacc caggaacaat acactgaaag tgaagaacag 3150

 ctggtggctt ctgaggagca gccaagccag gacgggaaac ctgaccttcc 3200

 caagagaaga ctcagtgagg gggttgagcc ctggcgagga cagctcaaga 3250

 aaagccctga ggctctgaag tgcagattaa cagaaggaag tgagaggctg 3300

 ccccgtcgct acagtgaggg tgacagggct gtcctcaggg gcttcagtga 3350

 gagcagcgag gaggaggagg agccggaaag ccctcggtca agctcgccac 3400

 caattctcac aaagcccacg ctgaagcgaa agaaaccatt tctccaccga 3450

 aggaggagag tccgaaagcg caaacaccac aatagcagtg tagtcacaga 3500

 aactatttct gagaccactg aagtgttaga tgaacctttt gaagattctg 3550

 actccgagag gccaatgcca agattagaac ccacatttga gatcgatgaa 3600

 gaagaggagg aagaggatga aaatgaactt ttccctagag aatacttccg 3650

 tcgtttgtct tcgcaggatg tactcaggtg tcagtcctct tctaagagga 3700

 agtctaaaga tgaagaagaa gatgaagagt cagatgatgc tgatgacact 3750

 cctatcttaa agccagtatc tcttttgcga aaacgtgatg tgaagaattc 3800

 tcctcttgag ccagatacat ccacaccttt gaaaaagaaa aagggatggc 3850

 ccaaaggcaa gagccgcaaa ccaatccact ggaagaaaag acctggtcga 3900

 aaaccaggat ttaagttgag tcgggaaatc atgccagttt ctactcaagc 3950

 atgcgtcatt gagcccatcg tttccattcc taaagctgga cgtaaaccca 4000

 agatccagga gagtgaagaa actgttgagc caaaagaaga catgccccta 4050

 cccgaggaga ggaaggagga ggaggagatg caagcagagg cagaagaggc 4100

 tgaagagggt gaggaagagg atgcagccag cagtgaagtc ccagcagcct 4150

 ctccagcaga cagcagcaat agtcctgaga ccgaaaccaa ggagcctgag 4200

 gtggaggagg aagaagagaa gccccgtgtc tcagaggagc agaggcagtc 4250

 agaggaggag cagcaggaat tagaggagcc agagccagag gaggaggaag 4300

 atgcagctgc agagactgcc cagaatgacg accacgacgc tgatgatgag 4350

 gatgatggcc acctggagtc cacaaagaaa aaggagctag aggaacagcc 4400

 cacgagggaa gatgtcaagg aggagcctgg tgttcaagag tcttttttag 4450

 atgctaatat gcagaagagt agggaaaaga taaaggataa agaggaaacc 4500

 gagctggatt ccgaagagga gcagccttcc catgacacgt ccgtggtgtc 4550

 agagcagatg gctgggtctg aggacgacca cgaagaagac tcccacacta 4600

 aggaagagtt aatcgaatta aaagaggagg aagagattcc tcatagtgag 4650

 ctggatctgg aaactgtaca ggcagtgcag tctttgactc aagaagaaag 4700

 cagtgagcat gagggcgcct accaggactg tgaggaaact cttgcggcgt 4750

 gtcagaccct gcagagttac acccaggctg acgaggaccc tcagatgtcc 4800

 atggttgaag actgtcatgc gtcagaacat aatagcccta tctcctccgt 4850

 tcagtctcac cccagccagt cagtccgttc ggtcagcagt cccaacgtgc 4900

 ctgcccttga gagtggctac acccagatca gcccagaaca aggatccctg 4950

 tccgcaccct ctatgcagaa catggagacc agccccatga tggatgtgcc 5000

 ttccgtatca gaccactctc agcaggtggt ggacagcggc ttcagtgacc 5050

 tgggcagcat tgagagcacc actgaaaact atgagaaccc aagcagttac 5100

 gactccacga tgggcggcag catctgtggg aacagctctt cccagagcag 5150

 ctgctcctac ggtgggctgt cgtcctccag cagcctcacc cagagcagct 5200

 gtgtggtcac tcagcagatg gccagcatgg gcagcagctg cagcatgatg 5250

 cagcagagca gcgtccagcc tgctgccaac tgcagcatca agtcacctca 5300

 gagctgcgtg gtggagaggc ctcccagtaa ccagcagcag cagccgccac 5350

 caccgcctcc acagcagcca cagccgccgc cgccacaacc acaaccagca 5400

 ccacagcctc caccacccca gcagcagccg caacagcagc cgcagcctca 5450

 gccccagcag cctccacccc caccccctcc ccagcagcag cccccgctgt 5500

 cacagtgtag tatgaataac agtttcaccc cagctcctat gatcatggag 5550

 ataccagaat ctggaagcac tgggaacata agtatctatg agaggattcc 5600

 aggggatttt ggtgccggca gctactctca accatcagcc accttcagcc 5650

 tagccaagct gcagcagctg accaacacca ttatggaccc tcatgccatg 5700

 ccttatagcc attctcctgc tgtgacttcc tatgcaacca gtgtttctct 5750

 gtccaataca ggactggctc agctggctcc atctcatccc ttagctggga 5800

 ctcctcaagc acaagccacc atgacgccac ccccaaactt ggcatccact 5850

 accatgaacc tcacatctcc tctgcttcag tgcaacatgt ctgccaccaa 5900

 cattggcatt cctcacacgc agagattgca agggcaaatg ccagtgaagg 5950

 ggcacatttc catccgctcc aagtctgcgc cactgccctc tgcggctgct 6000

 caccagcagc agctgtatgg ccgtagccca tcggcagttg ccatgcaggc 6050

 tggccctcgc gcactggctg ttcagcgtgg catgaacatg ggggttaatc 6100

 tgatgcctac tcccgcctat aatgtcaatt ccatgaatat gaacaccttg 6150

 aatgccatga acagctatcg aatgacacag cccatgatga acagcagtta 6200

 ccatagtaac cctgcctaca tgaaccagac agcacagtat cctatgcaga 6250

 tgcagatggg aatgatgggg agccaggcct atacccagca gcctatgcag 6300

 cctaaccctc atgggaacat gatgtacaca ggcccctccc atcacagcta 6350

 catgaacgct gctggcgtgc ccaagcagtc actcaacgga ccttacatga 6400

 gaagatgagc aagatgaact tgcaatcaaa aacttaaata tatataaata 6450

 aaggaacctt ttatactgac aaaccagaga aaaatggacc tttttccagt 6500

 taaaatattg ctgtagattt agaggaattt ttctttggtt tattttattt 6550

 tttagaaaac ctgatcttct cttttttttg ggttcatttt gttgtgggtt 6600

 ttggttttct tcacaatctt gaacatttta cagtagaact catctaaaaa 6650

 tggatttggg gatggggaaa catgcacaaa atcttttcat aattaaaaag 6700

 agccttactt tctttacata ccacatggac agaatttgtg taaaagtgaa 6750

 ttatctttat tttaaaatgt atgtttcccc tcactgtttg cagctcccaa 6800

 tgttgtcatt tttaaatgtt atatacatct caagggttaa ccagaccctt 6850

 tcctccaaac ccaacctttc atttcctact tcattccagc aggaggcact 6900

 taggggagac tcggatgggg acatggagaa caacccaagc tccttaaact 6950

 tattattatt gttaatatta ttattattat tattaataaa gtgaggcagg 7000

 aaaatgcttc tccttttaaa atcccctcca ctcctcacac acacacacct 7050

 cttgaaaccc ttccccaaga atgtttcttt atagacggac ttcattgaaa 7100

 tctttgttgt tcttgaatca agtgtaatat aatttttttc ttctttttta 7150

 aaatattccc actcagcact cagagacaca aaaatactgt aagtctcaat 7200

 taacagcaga atctcagaga aaagctgttt gcaatccaaa tccagccttt 7250

 ggaggaatag agatggtcaa ttaacaatca aaaagaggag attaacctct 7300

 tgttttttta ccacctggtg aatcagccat aacgcacaca cacgccaccc 7350

 agcctcttgt ttctagtatg tactttgaaa tgctaactga gggtcttgat 7400

 gcttgagcct ttgactgata aaactcaaat agcagtcccc agtgatttgc 7450

 ctcttaggtt ctttcttaaa ttgttggtgg atgactgtac attttagtga 7500

 tttgaaaaat aactgacaaa ccattgaaac agtttatttt atgttggaag 7550

 agatggcgca gatgtgtgtc agaagggaga tcacggtgtg agtttcgtag 7600

 ctatttaagt gatacatacc tctagttttt gtatgtcttt tgagatcctg 7650

 agttcatccc ctgtgaatca gagtgcacaa gcacctctcc tgtgagtggc 7700

 taatgagaag agggacagac cgaccaccag cacagtaggg cagatctgga 7750

 cagcagaatg ttataacgca agttcatgtg ttgctcccaa ctccattctc 7800

 ttttctctcg tgcaaccagt ttgcccattc tcttcctatt acttgctcca 7850

 gggataggta aaaaaaaaa 7869

<210> 2991
<211> 2004
<212> PRT
<213> Homo sapien

<400> 2991
 Met Val Lys Leu Ala Asn Pro Leu Tyr Thr Glu Trp Ile Leu Glu
   1               5                  10                  15

 Ala Ile Lys Lys Val Lys Lys Gln Lys Gln Arg Pro Ser Glu Glu
                  20                  25                  30

 Arg Ile Cys Asn Ala Val Ser Ser Ser His Gly Leu Asp Arg Lys
                  35                  40                  45

 Thr Val Leu Glu Gln Leu Glu Leu Ser Val Lys Asp Gly Thr Ile
                  50                  55                  60

 Leu Lys Val Ser Asn Lys Gly Leu Asn Ser Tyr Lys Asp Pro Asp
                  65                  70                  75

 Asn Pro Gly Arg Ile Ala Leu Pro Lys Pro Arg Asn His Gly Lys
                  80                  85                  90

 Leu Asp Asn Lys Gln Asn Val Asp Trp Asn Lys Leu Ile Lys Arg
                  95                 100                 105

 Ala Val Glu Gly Leu Ala Glu Ser Gly Gly Ser Thr Leu Lys Ser
                 110                 115                 120

 Ile Glu Arg Phe Leu Lys Gly Gln Lys Asp Val Ser Ala Leu Phe
                 125                 130                 135

 Gly Gly Ser Ala Ala Ser Gly Phe His Gln Gln Leu Arg Leu Ala
                 140                 145                 150

 Ile Lys Arg Ala Ile Gly His Gly Arg Leu Leu Lys Asp Gly Pro
                 155                 160                 165

 Leu Tyr Arg Leu Asn Thr Lys Ala Thr Asn Val Asp Gly Lys Glu
                 170                 175                 180

 Ser Cys Glu Ser Leu Ser Cys Leu Pro Pro Val Ser Leu Leu Pro
                 185                 190                 195

 His Glu Lys Asp Lys Pro Val Ala Glu Pro Ile Pro Ile Cys Ser
                 200                 205                 210

 Phe Cys Leu Gly Thr Lys Glu Gln Asn Arg Glu Lys Lys Pro Glu
                 215                 220                 225

 Glu Leu Ile Ser Cys Ala Asp Cys Gly Asn Ser Gly His Pro Ser
                 230                 235                 240

 Cys Leu Lys Phe Ser Pro Glu Leu Thr Val Arg Val Lys Ala Leu
                 245                 250                 255

 Arg Trp Gln Cys Ile Glu Cys Lys Thr Cys Ser Ser Cys Arg Asp
                 260                 265                 270

 Gln Gly Lys Asn Ala Asp Asn Met Leu Phe Cys Asp Ser Cys Asp
                 275                 280                 285

 Arg Gly Phe His Met Glu Cys Cys Asp Pro Pro Leu Thr Arg Met
                 290                 295                 300

 Pro Lys Gly Met Trp Ile Cys Gln Ile Cys Arg Pro Arg Lys Lys
                 305                 310                 315

 Gly Arg Lys Leu Leu Gln Lys Lys Ala Ala Gln Ile Lys Arg Arg
                 320                 325                 330

 Tyr Thr Asn Pro Ile Gly Arg Pro Lys Asn Arg Leu Lys Lys Gln
                 335                 340                 345

 Asn Thr Val Ser Lys Gly Pro Phe Ser Lys Val Arg Thr Gly Pro
                 350                 355                 360

 Gly Arg Gly Arg Lys Arg Lys Ile Thr Leu Ser Ser Gln Ser Ala
                 365                 370                 375

 Ser Ser Ser Ser Glu Glu Gly Tyr Leu Glu Arg Ile Asp Gly Leu
                 380                 385                 390

 Asp Phe Cys Arg Asp Ser Asn Val Ser Leu Arg Phe Asn Lys Lys
                 395                 400                 405

 Thr Lys Gly Leu Ile Asp Gly Leu Thr Lys Phe Phe Thr Pro Ser
                 410                 415                 420

 Pro Asp Gly Arg Lys Ala Arg Gly Glu Val Val Asp Tyr Ser Glu
                 425                 430                 435

 Gln Tyr Arg Ile Arg Lys Arg Gly Asn Arg Lys Ser Ser Thr Ser
                 440                 445                 450

 Asp Trp Pro Thr Asp Asn Gln Asp Gly Trp Asp Gly Lys Gln Glu
                 455                 460                 465

 Asn Glu Glu Arg Leu Phe Gly Ser Gln Glu Ile Met Thr Glu Lys
                 470                 475                 480

 Asp Met Glu Leu Phe Arg Asp Ile Gln Glu Gln Ala Leu Gln Lys
                 485                 490                 495

 Val Gly Val Thr Gly Pro Pro Asp Pro Gln Val Arg Cys Pro Ser
                 500                 505                 510

 Val Ile Glu Phe Gly Lys Tyr Glu Ile His Thr Trp Tyr Ser Ser
                 515                 520                 525

 Pro Tyr Pro Gln Glu Tyr Ser Arg Leu Pro Lys Leu Tyr Leu Cys
                 530                 535                 540

 Glu Phe Cys Leu Lys Tyr Met Lys Ser Arg Thr Ile Leu Gln Gln
                 545                 550                 555

 His Met Lys Lys Cys Gly Trp Phe His Pro Pro Ala Asn Glu Ile
                 560                 565                 570

 Tyr Arg Lys Asn Asn Ile Ser Val Phe Glu Val Asp Gly Asn Val
                 575                 580                 585

 Ser Thr Ile Tyr Cys Gln Asn Leu Cys Leu Leu Ala Lys Leu Phe
                 590                 595                 600

 Leu Asp His Lys Thr Leu Tyr Tyr Asp Val Glu Pro Phe Leu Phe
                 605                 610                 615

 Tyr Val Leu Thr Gln Asn Asp Val Lys Gly Cys His Leu Val Gly
                 620                 625                 630

 Tyr Phe Ser Lys Glu Lys His Cys Gln Gln Lys Tyr Asn Val Ser
                 635                 640                 645

 Cys Ile Met Ile Leu Pro Gln Tyr Gln Arg Lys Gly Tyr Gly Arg
                 650                 655                 660

 Phe Leu Ile Asp Phe Ser Tyr Leu Leu Ser Lys Arg Glu Gly Gln
                 665                 670                 675

 Ala Gly Ser Pro Glu Lys Pro Leu Ser Asp Leu Gly Arg Leu Ser
                 680                 685                 690

 Tyr Met Ala Tyr Trp Lys Ser Val Ile Leu Glu Cys Leu Tyr His
                 695                 700                 705

 Gln Asn Asp Lys Gln Ile Ser Ile Lys Lys Leu Ser Lys Leu Thr
                 710                 715                 720

 Gly Ile Cys Pro Gln Asp Ile Thr Ser Thr Leu His His Leu Arg
                 725                 730                 735

 Met Leu Asp Phe Arg Ser Asp Gln Phe Val Ile Ile Arg Arg Glu
                 740                 745                 750

 Lys Leu Ile Gln Asp His Met Ala Lys Leu Gln Leu Asn Leu Arg
                 755                 760                 765

 Pro Val Asp Val Asp Pro Glu Cys Leu Arg Trp Thr Pro Val Ile
                 770                 775                 780

 Val Ser Asn Ser Val Val Ser Glu Glu Glu Glu Glu Glu Ala Glu
                 785                 790                 795

 Glu Gly Glu Asn Glu Glu Pro Gln Cys Gln Glu Arg Glu Leu Glu
                 800                 805                 810

 Ile Ser Val Gly Lys Ser Val Ser His Glu Asn Lys Glu Gln Asp
                 815                 820                 825

 Ser Tyr Ser Val Glu Ser Glu Lys Lys Pro Glu Val Met Ala Pro
                 830                 835                 840

 Val Ser Ser Thr Arg Leu Ser Lys Gln Val Leu Pro His Asp Ser
                 845                 850                 855

 Leu Pro Ala Asn Ser Gln Pro Ser Arg Arg Gly Arg Trp Gly Arg
                 860                 865                 870

 Lys Asn Arg Lys Thr Gln Glu Arg Phe Gly Asp Lys Asp Ser Lys
                 875                 880                 885

 Leu Leu Leu Glu Glu Thr Ser Ser Ala Pro Gln Glu Gln Tyr Gly
                 890                 895                 900

 Glu Cys Gly Glu Lys Ser Glu Ala Thr Gln Glu Gln Tyr Thr Glu
                 905                 910                 915

 Ser Glu Glu Gln Leu Val Ala Ser Glu Glu Gln Pro Ser Gln Asp
                 920                 925                 930

 Gly Lys Pro Asp Leu Pro Lys Arg Arg Leu Ser Glu Gly Val Glu
                 935                 940                 945

 Pro Trp Arg Gly Gln Leu Lys Lys Ser Pro Glu Ala Leu Lys Cys
                 950                 955                 960

 Arg Leu Thr Glu Gly Ser Glu Arg Leu Pro Arg Arg Tyr Ser Glu
                 965                 970                 975

 Gly Asp Arg Ala Val Leu Arg Gly Phe Ser Glu Ser Ser Glu Glu
                 980                 985                 990

 Glu Glu Glu Pro Glu Ser Pro Arg Ser Ser Ser Pro Pro Ile Leu
                 995                1000                1005

 Thr Lys Pro Thr Leu Lys Arg Lys Lys Pro Phe Leu His Arg Arg
                1010                1015                1020

 Arg Arg Val Arg Lys Arg Lys His His Asn Ser Ser Val Val Thr
                1025                1030                1035

 Glu Thr Ile Ser Glu Thr Thr Glu Val Leu Asp Glu Pro Phe Glu
                1040                1045                1050

 Asp Ser Asp Ser Glu Arg Pro Met Pro Arg Leu Glu Pro Thr Phe
                1055                1060                1065

 Glu Ile Asp Glu Glu Glu Glu Glu Glu Asp Glu Asn Glu Leu Phe
                1070                1075                1080

 Pro Arg Glu Tyr Phe Arg Arg Leu Ser Ser Gln Asp Val Leu Arg
                1085                1090                1095

 Cys Gln Ser Ser Ser Lys Arg Lys Ser Lys Asp Glu Glu Glu Asp
                1100                1105                1110

 Glu Glu Ser Asp Asp Ala Asp Asp Thr Pro Ile Leu Lys Pro Val
                1115                1120                1125

 Ser Leu Leu Arg Lys Arg Asp Val Lys Asn Ser Pro Leu Glu Pro
                1130                1135                1140

 Asp Thr Ser Thr Pro Leu Lys Lys Lys Lys Gly Trp Pro Lys Gly
                1145                1150                1155

 Lys Ser Arg Lys Pro Ile His Trp Lys Lys Arg Pro Gly Arg Lys
                1160                1165                1170

 Pro Gly Phe Lys Leu Ser Arg Glu Ile Met Pro Val Ser Thr Gln
                1175                1180                1185

 Ala Cys Val Ile Glu Pro Ile Val Ser Ile Pro Lys Ala Gly Arg
                1190                1195                1200

 Lys Pro Lys Ile Gln Glu Ser Glu Glu Thr Val Glu Pro Lys Glu
                1205                1210                1215

 Asp Met Pro Leu Pro Glu Glu Arg Lys Glu Glu Glu Glu Met Gln
                1220                1225                1230

 Ala Glu Ala Glu Glu Ala Glu Glu Gly Glu Glu Glu Asp Ala Ala
                1235                1240                1245

 Ser Ser Glu Val Pro Ala Ala Ser Pro Ala Asp Ser Ser Asn Ser
                1250                1255                1260

 Pro Glu Thr Glu Thr Lys Glu Pro Glu Val Glu Glu Glu Glu Glu
                1265                1270                1275

 Lys Pro Arg Val Ser Glu Glu Gln Arg Gln Ser Glu Glu Glu Gln
                1280                1285                1290

 Gln Glu Leu Glu Glu Pro Glu Pro Glu Glu Glu Glu Asp Ala Ala
                1295                1300                1305

 Ala Glu Thr Ala Gln Asn Asp Asp His Asp Ala Asp Asp Glu Asp
                1310                1315                1320

 Asp Gly His Leu Glu Ser Thr Lys Lys Lys Glu Leu Glu Glu Gln
                1325                1330                1335

 Pro Thr Arg Glu Asp Val Lys Glu Glu Pro Gly Val Gln Glu Ser
                1340                1345                1350

 Phe Leu Asp Ala Asn Met Gln Lys Ser Arg Glu Lys Ile Lys Asp
                1355                1360                1365

 Lys Glu Glu Thr Glu Leu Asp Ser Glu Glu Glu Gln Pro Ser His
                1370                1375                1380

 Asp Thr Ser Val Val Ser Glu Gln Met Ala Gly Ser Glu Asp Asp
                1385                1390                1395

 His Glu Glu Asp Ser His Thr Lys Glu Glu Leu Ile Glu Leu Lys
                1400                1405                1410

 Glu Glu Glu Glu Ile Pro His Ser Glu Leu Asp Leu Glu Thr Val
                1415                1420                1425

 Gln Ala Val Gln Ser Leu Thr Gln Glu Glu Ser Ser Glu His Glu
                1430                1435                1440

 Gly Ala Tyr Gln Asp Cys Glu Glu Thr Leu Ala Ala Cys Gln Thr
                1445                1450                1455

 Leu Gln Ser Tyr Thr Gln Ala Asp Glu Asp Pro Gln Met Ser Met
                1460                1465                1470

 Val Glu Asp Cys His Ala Ser Glu His Asn Ser Pro Ile Ser Ser
                1475                1480                1485

 Val Gln Ser His Pro Ser Gln Ser Val Arg Ser Val Ser Ser Pro
                1490                1495                1500

 Asn Val Pro Ala Leu Glu Ser Gly Tyr Thr Gln Ile Ser Pro Glu
                1505                1510                1515

 Gln Gly Ser Leu Ser Ala Pro Ser Met Gln Asn Met Glu Thr Ser
                1520                1525                1530

 Pro Met Met Asp Val Pro Ser Val Ser Asp His Ser Gln Gln Val
                1535                1540                1545

 Val Asp Ser Gly Phe Ser Asp Leu Gly Ser Ile Glu Ser Thr Thr
                1550                1555                1560

 Glu Asn Tyr Glu Asn Pro Ser Ser Tyr Asp Ser Thr Met Gly Gly
                1565                1570                1575

 Ser Ile Cys Gly Asn Ser Ser Ser Gln Ser Ser Cys Ser Tyr Gly
                1580                1585                1590

 Gly Leu Ser Ser Ser Ser Ser Leu Thr Gln Ser Ser Cys Val Val
                1595                1600                1605

 Thr Gln Gln Met Ala Ser Met Gly Ser Ser Cys Ser Met Met Gln
                1610                1615                1620

 Gln Ser Ser Val Gln Pro Ala Ala Asn Cys Ser Ile Lys Ser Pro
                1625                1630                1635

 Gln Ser Cys Val Val Glu Arg Pro Pro Ser Asn Gln Gln Gln Gln
                1640                1645                1650

 Pro Pro Pro Pro Pro Pro Gln Gln Pro Gln Pro Pro Pro Pro Gln
                1655                1660                1665

 Pro Gln Pro Ala Pro Gln Pro Pro Pro Pro Gln Gln Gln Pro Gln
                1670                1675                1680

 Gln Gln Pro Gln Pro Gln Pro Gln Gln Pro Pro Pro Pro Pro Pro
                1685                1690                1695

 Pro Gln Gln Gln Pro Pro Leu Ser Gln Cys Ser Met Asn Asn Ser
                1700                1705                1710

 Phe Thr Pro Ala Pro Met Ile Met Glu Ile Pro Glu Ser Gly Ser
                1715                1720                1725

 Thr Gly Asn Ile Ser Ile Tyr Glu Arg Ile Pro Gly Asp Phe Gly
                1730                1735                1740

 Ala Gly Ser Tyr Ser Gln Pro Ser Ala Thr Phe Ser Leu Ala Lys
                1745                1750                1755

 Leu Gln Gln Leu Thr Asn Thr Ile Met Asp Pro His Ala Met Pro
                1760                1765                1770

 Tyr Ser His Ser Pro Ala Val Thr Ser Tyr Ala Thr Ser Val Ser
                1775                1780                1785

 Leu Ser Asn Thr Gly Leu Ala Gln Leu Ala Pro Ser His Pro Leu
                1790                1795                1800

 Ala Gly Thr Pro Gln Ala Gln Ala Thr Met Thr Pro Pro Pro Asn
                1805                1810                1815

 Leu Ala Ser Thr Thr Met Asn Leu Thr Ser Pro Leu Leu Gln Cys
                1820                1825                1830

 Asn Met Ser Ala Thr Asn Ile Gly Ile Pro His Thr Gln Arg Leu
                1835                1840                1845

 Gln Gly Gln Met Pro Val Lys Gly His Ile Ser Ile Arg Ser Lys
                1850                1855                1860

 Ser Ala Pro Leu Pro Ser Ala Ala Ala His Gln Gln Gln Leu Tyr
                1865                1870                1875

 Gly Arg Ser Pro Ser Ala Val Ala Met Gln Ala Gly Pro Arg Ala
                1880                1885                1890

 Leu Ala Val Gln Arg Gly Met Asn Met Gly Val Asn Leu Met Pro
                1895                1900                1905

 Thr Pro Ala Tyr Asn Val Asn Ser Met Asn Met Asn Thr Leu Asn
                1910                1915                1920

 Ala Met Asn Ser Tyr Arg Met Thr Gln Pro Met Met Asn Ser Ser
                1925                1930                1935

 Tyr His Ser Asn Pro Ala Tyr Met Asn Gln Thr Ala Gln Tyr Pro
                1940                1945                1950

 Met Gln Met Gln Met Gly Met Met Gly Ser Gln Ala Tyr Thr Gln
                1955                1960                1965

 Gln Pro Met Gln Pro Asn Pro His Gly Asn Met Met Tyr Thr Gly
                1970                1975                1980

 Pro Ser His His Ser Tyr Met Asn Ala Ala Gly Val Pro Lys Gln
                1985                1990                1995

 Ser Leu Asn Gly Pro Tyr Met Arg Arg
                2000

<210> 2992
<211> 660
<212> DNA
<213> Homo sapien

<400> 2992
 ctgaaaaaaa tggataaaga aggtaaaaca ttaaaaaaac ataaattgaa 50

 gcataaagag agggaaaaag aaaagcataa aaaagaaatt gaaggtgaaa 100

 aggaaaaata caaaactaag gatagtgcca aagaactgca gaggagtgtg 150

 gaatttgata gagaattttg ggaaagagaa tttttttaaa agtgatgaaa 200

 ctgaagatct ctttttaaat atggaacatg aatccttaac attagaaaaa 250

 aaatcaaaat tggaaaaaaa catcaaagat gataaatcaa ccaaggaaaa 300

 gcatgtgtca aaagagagga actttaaaga ggaacgagac aagattaaaa 350

 aggaaagcga gaatttactt ctttggggta tgagtgccat tgaggaatct 400

 atagggcttc atttagtgga aaaggaaata gacattgaaa aacaagaaaa 450

 gcatataaag gaaagtaaag aaaaacctga gaagcgatct caaattaaag 500

 aaaaggacat tgagaagatg gaaagaaaaa cctttgacaa aggacaagct 550

 tatattcgca tcacacagac aaaatggcca tacaagaagg gtgagaagga 600

 gcaaaaatac tgctgcttat taaaaaaacc tgacggacag agagaaaagt 650

 aggagaaagg 660

<210> 2993
<211> 1807
<212> DNA
<213> Homo sapien

<400> 2993
 ctggaaggag tcatggcgga tggtcaggtg gcggaactgc tgctccggcg 50

 gctggaggcg tctgatggcg gcctggacag cgccgagttg gcggctgagc 100

 tgggcatgga gcaccaggcg gtggtgggcg ccgtgaagag ccttcaggcg 150

 ctgggcgagg tcatcgaggc tgaacttcgg tccaccaagc actgggagct 200

 tactgcggag ggcgaggaga ttgcccggga gggcagccat gaggcccgtg 250

 tgtttcgaag cattccccca gagggcctgg cccagagcga gcttatgcga 300

 ctgcccagtg gcaaagtggg cttcagcaag gccatgtcca acaagtggat 350

 tcgggtggac aagagtgcgg ctgacgggcc ccgggtgttc cgagtggtgg 400

 acagcatgga ggatgaggtg cagcggcggc tccagctggt ccggggggga 450

 caggctgaga agctggggga gaaggagagg agcgagctga ggaagaggaa 500

 gctgttggct gaagtgactc tgaagaccta ctgggtgagc aaaggcagtg 550

 cctttagtac cagcatctcc aagcaagaga cagagctgag cccagagatg 600

 atctccagtg gctcttggcg ggaccggccc ttcaagccct acaacttctt 650

 ggcccacggt gtcctccccg acagcggcca ccttcacccg ctgctcaagg 700

 tccgctccca gttccgacag atcttcctgg agatggggtt caccgagatg 750

 ccgactgata acttcattga gagctccttc tggaactttg acgccctctt 800

 ccagccccag cagcacccag cccgtgacca gcacgacacc ttcttccttc 850

 gagatccagc ggaggccctg cagctcccaa tggactatgt ccagcgggtc 900

 aagcggaccc actctcaggg cggctacggc tcacaggggt acaagtataa 950

 ctggaagctg gacgaggccc ggaaaaacct actgcgaacc cacaccacat 1000

 cagccagcgc ccgtgcgctc taccgccttg cccagaagaa gcccttcact 1050

 ccggtcaagt acttctccat cgaccgcgta ttccggaatg agaccctgga 1100

 cgccacgcac ctggctgagt tccaccagat cgagggcgtg gtggcggatc 1150

 atggtctcac cttgggccac ctcatgggcg ttctgcggga gttcttcacc 1200

 aagctgggta tcacgcaact ccgcttcaag ccagcctaca acccatacac 1250

 agagcccagc atggaggtgt tcagctacca ccaaggcctg aagaagtggg 1300

 tggaggtcgg aaactcgggg gtcttccgtc cagagatgct gctgcccatg 1350

 gggcttcccg agaacgtgtc ggtcattgcc tggggcctct ccctggagcg 1400

 cccaacgatg atcaaatatg gcatcaacaa tatccgggag ctggtgggcc 1450

 acaaggtgaa cctgcagatg gtgtatgaca gtcccctgtg ccgcctggat 1500

 gccgagccga ggccccctcc cacacaggag gctgcgtgac atgggccact 1550

 ctaggacagg tcatcctccc cgagtccctg ctgctgcgct cctttgcatc 1600

 cctggccagt gaccttgtat ttatgaggct ctgtgaggcc agcccccacc 1650

 ttcctctttc ccacctgtcc caggaccaga atcccaggga cagaggactg 1700

 ggtagcaggt tccttctgtt gtcctgtgtg gtgtgtctac tgtgagggtg 1750

 ggccctgagg agacctgtgg gccacctatt gtctaataaa gtgggcagtt 1800

 gccccca 1807

<210> 2994
<211> 508
<212> PRT
<213> Homo sapien

<400> 2994
 Met Ala Asp Gly Gln Val Ala Glu Leu Leu Leu Arg Arg Leu Glu
   1               5                  10                  15

 Ala Ser Asp Gly Gly Leu Asp Ser Ala Glu Leu Ala Ala Glu Leu
                  20                  25                  30

 Gly Met Glu His Gln Ala Val Val Gly Ala Val Lys Ser Leu Gln
                  35                  40                  45

 Ala Leu Gly Glu Val Ile Glu Ala Glu Leu Arg Ser Thr Lys His
                  50                  55                  60

 Trp Glu Leu Thr Ala Glu Gly Glu Glu Ile Ala Arg Glu Gly Ser
                  65                  70                  75

 His Glu Ala Arg Val Phe Arg Ser Ile Pro Pro Glu Gly Leu Ala
                  80                  85                  90

 Gln Ser Glu Leu Met Arg Leu Pro Ser Gly Lys Val Gly Phe Ser
                  95                 100                 105

 Lys Ala Met Ser Asn Lys Trp Ile Arg Val Asp Lys Ser Ala Ala
                 110                 115                 120

 Asp Gly Pro Arg Val Phe Arg Val Val Asp Ser Met Glu Asp Glu
                 125                 130                 135

 Val Gln Arg Arg Leu Gln Leu Val Arg Gly Gly Gln Ala Glu Lys
                 140                 145                 150

 Leu Gly Glu Lys Glu Arg Ser Glu Leu Arg Lys Arg Lys Leu Leu
                 155                 160                 165

 Ala Glu Val Thr Leu Lys Thr Tyr Trp Val Ser Lys Gly Ser Ala
                 170                 175                 180

 Phe Ser Thr Ser Ile Ser Lys Gln Glu Thr Glu Leu Ser Pro Glu
                 185                 190                 195

 Met Ile Ser Ser Gly Ser Trp Arg Asp Arg Pro Phe Lys Pro Tyr
                 200                 205                 210

 Asn Phe Leu Ala His Gly Val Leu Pro Asp Ser Gly His Leu His
                 215                 220                 225

 Pro Leu Leu Lys Val Arg Ser Gln Phe Arg Gln Ile Phe Leu Glu
                 230                 235                 240

 Met Gly Phe Thr Glu Met Pro Thr Asp Asn Phe Ile Glu Ser Ser
                 245                 250                 255

 Phe Trp Asn Phe Asp Ala Leu Phe Gln Pro Gln Gln His Pro Ala
                 260                 265                 270

 Arg Asp Gln His Asp Thr Phe Phe Leu Arg Asp Pro Ala Glu Ala
                 275                 280                 285

 Leu Gln Leu Pro Met Asp Tyr Val Gln Arg Val Lys Arg Thr His
                 290                 295                 300

 Ser Gln Gly Gly Tyr Gly Ser Gln Gly Tyr Lys Tyr Asn Trp Lys
                 305                 310                 315

 Leu Asp Glu Ala Arg Lys Asn Leu Leu Arg Thr His Thr Thr Ser
                 320                 325                 330

 Ala Ser Ala Arg Ala Leu Tyr Arg Leu Ala Gln Lys Lys Pro Phe
                 335                 340                 345

 Thr Pro Val Lys Tyr Phe Ser Ile Asp Arg Val Phe Arg Asn Glu
                 350                 355                 360

 Thr Leu Asp Ala Thr His Leu Ala Glu Phe His Gln Ile Glu Gly
                 365                 370                 375

 Val Val Ala Asp His Gly Leu Thr Leu Gly His Leu Met Gly Val
                 380                 385                 390

 Leu Arg Glu Phe Phe Thr Lys Leu Gly Ile Thr Gln Leu Arg Phe
                 395                 400                 405

 Lys Pro Ala Tyr Asn Pro Tyr Thr Glu Pro Ser Met Glu Val Phe
                 410                 415                 420

 Ser Tyr His Gln Gly Leu Lys Lys Trp Val Glu Val Gly Asn Ser
                 425                 430                 435

 Gly Val Phe Arg Pro Glu Met Leu Leu Pro Met Gly Leu Pro Glu
                 440                 445                 450

 Asn Val Ser Val Ile Ala Trp Gly Leu Ser Leu Glu Arg Pro Thr
                 455                 460                 465

 Met Ile Lys Tyr Gly Ile Asn Asn Ile Arg Glu Leu Val Gly His
                 470                 475                 480

 Lys Val Asn Leu Gln Met Val Tyr Asp Ser Pro Leu Cys Arg Leu
                 485                 490                 495

 Asp Ala Glu Pro Arg Pro Pro Pro Thr Gln Glu Ala Ala
                 500                 505

<210> 2995
<211> 8467
<212> DNA
<213> Homo sapien

<400> 2995
 ttccccaaat tgatggacat aaacccatat gcttatctca gcatgtgttt 50

 aaaaagcact tgctgagatt cagtgaccat ccaacattaa aaactgctga 100

 tagaaggaaa ctcacttagc tgaattaagg acgtgttctt aaaatctacc 150

 gccaacgtaa tggggaggag ctcacggcgt tcgttaattt attcattccg 200

 caaatatgtt ttgggcagtt acataccgaa tagtagatgg aggtgtgcct 250

 gctgtcatgg agatagggtg atttcatcct gttgatcagg aaaactccta 300

 ggtgcttgca ggtaaatgtg ccacaaagaa agtgaggacc aaaggttagt 350

 tgatgtaaaa acaagtttga aatgcatttt ggggtaattt atccggtcgc 400

 ttcgggcatt cctcgcggaa ggcgtggtct ggtgactcag aagccaacac 450

 actgcgggag tccagccgtc ggccccctgc cgtgtggcga ggcccagtgt 500

 gtcccctttg taaggacagc acaagcagga gttaatggac cggccatcca 550

 tagcggtggt ggggcaggga gccagtttcc gaaagaaact cacgccgccg 600

 caggagggcc ctgtgggatg ctctgtgcag agctgttgtg cggaccggga 650

 gacgggaaag cctggtggct gcaggagggc accgtgcaga agtatccagt 700

 aaaccaccca cagcacggca gcagaaaaac gaggaaatta tatgtgtgta 750

 tgtttataag aactcagaag caatggtgag caaaaagcaa aagcaagagg 800

 agaaagtcac agtgtgctgg catcaagttg cattgagagg agcccgcggg 850

 gtagtgcacc cgcatttcct cgttgcgttg agaggcgccc gcggggtagt 900

 gcacccgcat ttcctcgttt gagaggcgcc cgcggggtag tgcacccgca 950

 tttcctagtt gccttgagag gtgccgcggg gtagtgcacc cgcatttcct 1000

 agttgccttg agaggtgccc gcggggtagt gcacccgcat ttcctagttg 1050

 ccttgagagg tgccgcgggg tagtgcaccc gcatttcctc gtttcattga 1100

 gcggtgcccg cggggtagtg cactcgcatt tcctagttgc cttgagaggt 1150

 gccgcggggt agtgcaccca catttcttca ctcgtttaga gttcggggct 1200

 ctcagaacac agggagaata tgggagaatt ccttactaga tgttacagag 1250

 gccacacagg gccacttttt tctttttttt ttattgtgtc aggtatacgt 1300

 aaatattcct ttcggtcagt tcagcacgta ggactgagtg gcattaggta 1350

 cgctcactgt acagccaatg cctccatagg ccacttttta aatacgcggg 1400

 gctaagggcc aacgacaaga ttgtcatcga ggacaataag tcgatggcgc 1450

 tgcctggtca ctggcttggt cagaaaacac atgccagggt gactggattt 1500

 aacgttcagt tttagaacca caaatctgcc agcccaggca ttcaagagga 1550

 agtgagtaat tcactgaatt gatggttagc aagacccttc aaagtccttg 1600

 gaagttccgt gtttgctggg ggtcacaaca gcaattgcgt ttctaaaaca 1650

 ttgaaaacca cccgtttttc acacatctga atagcctgag ttgtaacaga 1700

 cctaagtaaa ggcgtccaaa cgtgcctgat cctgtggctg ggtcccagga 1750

 gccttaacaa ggcattgaga gagctggatt gattgattag actcttgcca 1800

 actgctgtgc ggaatacaga aaatgcagct ccagctctca aagggctgaa 1850

 aatctaattg aggtgaaaaa ggtaacatgt gtgaaaacca tgtctgtgta 1900

 gacttgtttt gtatggacca gaaaagttgg aagtccagag atggatgcga 1950

 ggaagtaggg gatggagttt ccttataacc tctggaggga cagtccagat 2000

 acataccggg gtgtgtagcg ggtggaggtt ctaagacagg ctggaggaac 2050

 agtgcagaca cacaccaggg tgtgtagggg gtagaggttc taagacagtc 2100

 tggagggaga gtgcagacac acaccggggt gtgtaagcag tggaggttct 2150

 aagacaggct ggaggaacag tggagacaca caccagggcg tgtagggggt 2200

 agaggttcta agacaggctg gaggaacagt ggagacacac accacggcgt 2250

 gtagggggta gaggttctaa gacagtctgg tgggagagtg cagacacacc 2300

 cggggccgtg tagggggtac aggttctaag acagtctggt gggagagtgc 2350

 agacacacac ggggctgtgt cggggataga ggttctaaga cagtctggtg 2400

 ggagagtgca gacacacacc agggcgtgta gggggtggag gttctaagac 2450

 aggctggagg aacagtggag acacacactg gggagcatag gggtgctttt 2500

 ctctgagtcc cctagtacat ggtagaggct gtagaccctc cgctcttggg 2550

 cacgtgggta ggctctcagg atgactcttg gctcttgggc atgtgggtga 2600

 gctctcagga tgatgcccag ccccaatttt caggcaattg tgcaaggact 2650

 tgacccattc atccgctgag ctgagttgct gagactgctg ggtgcccggg 2700

 tggtgatcat tgtccgtggc atacagaaca cactgcagct tctgcaaagt 2750

 gagctcattt cacgcatttt atggctttgc caggctgctg ttgacctgcc 2800

 agaactttta atcagacatt tggaggacct gttttgtagt cagtggagaa 2850

 atattacaag gatagggtaa tttgaaatat ctaaggattg taagtgacaa 2900

 gttcatgtct aattttgcat ttccagtgaa agcaagtgtt ggctttgaat 2950

 gttacttatg tgctgagatg tgtatattcc tcagtgctta attactaagg 3000

 atttttaggg ccaagttttg ttacagtgaa tgattgtgga tgcataaaga 3050

 ataaatttaa tatttttaag gcatggagat tatttgtatc taagaaacca 3100

 ggtaaaataa agaaacattt atgcttgtgt gactgataaa agagttagag 3150

 agacactcat attctgggag tttgaagaat gtcattttca ttctctaaaa 3200

 gtcttgttag tgtcacagca ttgaaaattt aaaaatccgt gtgtattttc 3250

 ttgctagtgc tggtacttga atatctgtat catccaccta tccatccacc 3300

 tacccatatt tctataatcc accgtccctc gacatgccta tcatctgtcc 3350

 accatttctc tctgtctaat tttcaaaaca tcctgtaagt ttatataaag 3400

 gaagattttt cttcttgtga agttctctaa ggctgacaag ttacctggca 3450

 tgactgtggc ggatgcccat agccaggtgg tcctcggggt acagatgggg 3500

 caggggcact tgtgagaaac acctgaagtg cttttcccca gcctccccgg 3550

 ccctgccggg tggtggaggc gctgcacggt gccttccatg gagcaagccc 3600

 ggggctccgc agggtcctca gcatgattca gatttccttc cacccccagc 3650

 tctagatgat ttggtaaaac cacaaacagg cacaaaacag cccacatgga 3700

 attctaaagt tttaatttca ttttggaatt tatgcactca gatgaaatga 3750

 tttatgatga tgttgagaat ggggatgaag gtggaaacag ctccttggaa 3800

 tacggatgga gttcgagtga atttgaaagt tacgaagagc agagtgactc 3850

 ggagtgcaag aatgggattc ccaggtcctt cctgcgcagc aaccacaaaa 3900

 agcaactttc tcatgaccta acccgtttaa aggagcacta tgagaaaaag 3950

 atgagagatt tgatggcaag cacggtgggc gtggtggaga ttcagcagct 4000

 caggcagaag catgaactga agatgcagaa gctcgtgaag gccgcgaagg 4050

 acggcaccaa ggacgggctg gagaggacca gggcagccgt gaagaggggc 4100

 cgctccttca tcaggaccaa gtctctcatc gcacaggatc acagatcttc 4150

 tcttgaggaa gaacagaatt tgttcattga tgttgactgc aagcacccgg 4200

 aagccatctt gaccccgatg cccgagggtt tatctcagca gcaggttgta 4250

 agaagatata tactgggttc agttgtcgac agtgaaaaga actacgtaga 4300

 tgctcttaag aggattttgg agcaatatga gaagccgctg tctgagatgg 4350

 agccaaaggt tctgagtgag aggaagctga agacggtgtt ctaccgagtc 4400

 aaagagatcc tgcagtgcca ctcgctattt cagatcgcgc tggccagccg 4450

 cgtttccgag tgggactccg tggaaatgat aggcgatgtc ttcgtggctt 4500

 cgttttctaa gtccatggtg ctggatgcat acagtgaata tgtgaacaat 4550

 ttcagcacag ccgtggcagt cctcaagaaa acatgtgcca caaagcccgc 4600

 ttttcttgaa tttttaaagc aggaacagga ggccagcccc gatcgaacca 4650

 cgctctacag cctgatgatg aagcccatcc agaggttccc acagttcatc 4700

 ctcctgctcc aggacatgct gaagaacacc tccaaaggcc accccgacag 4750

 gctgcctctt cagatggccc tgacagagct cgaaacacta gcagagaagt 4800

 taaatgaaag aaagagagat gctgatcaac gctgtgaagt gaagcaaata 4850

 gccaaagcca taaacgaaag atacctgaac aagcttctca gcagtggaag 4900

 ccgatacctc attcgatcag atgatatgat agaaacagtt tacaacgaca 4950

 gaggagagat tgttaaaacc aaagaacgcc gagtcttcat gttaaatgat 5000

 gtgttaatgt gtgccaccgt cagctcacgc ccctctcatg acagccgtgt 5050

 gatgagcagc cagaggtact tgctgaagtg gagcgttcca ctgggacatg 5100

 tggacgccat cgagtatggc agcagcgcag gcacgggcga gcacagcagg 5150

 caccttgccg ttcacccgcc ggagagcctg gccgtggttg ctaacgcgaa 5200

 accaaacaaa gtttacatgg ggccaggaca actgtatcaa gatttacaaa 5250

 acttgttgca tgacttaaat gtaattggcc aaatcactca gctgatagga 5300

 aaccttaaag gaaactatca gaacttaaac cagtcagtag cccatgactg 5350

 gacatcaggt ttacaaaggc ttattttgaa gaaagaagat gaaatcagag 5400

 ctgcggactg ctgcagaatt cagttacagc ttcccgggaa gcaggacaaa 5450

 tctgggcgac cgacgttctt tacagctgtg ttcaatacgt tcacccctgc 5500

 catcaaggag tcctgggtca acagcttaca gatggccaag ctcgccctag 5550

 aagaggagaa ccacatgggc tggttctgtg tggaagacga tgggaatcac 5600

 attaaaaagg agaagcatcc tctcctcgtc ggacacatgc ccgtgatggt 5650

 ggccaagcag caggagttca agattgaatg tgctgcttat aaccctgaac 5700

 cttacctaaa taatgaaagc cagccagatt cattttccac ggcacatggt 5750

 ttcctgtgga tcggaagttg cacccatcaa atgggtcaga ttgccatcgt 5800

 ctcgtttcaa aattccactc ccaaagtcat tgagtgcttc aacgtggaat 5850

 ctcgcatcct gtgcatgctg tacgttcccg tcgaggagaa gcgcagagag 5900

 cctggggcac ccccggaccc cgagaccccg gccgtgagag cttctgatgt 5950

 ccccacgatc tgtgtaggga cggaggaggg aagcatttcc atttataaaa 6000

 gcagtcaagg ctccaagaaa gtgagacttc agcacttttt cactcctgag 6050

 aagtccacag tcatgagcct ggcttgcacg tctcagagcc tgtacgctgg 6100

 cctggtcaac ggggcagtcg ccagctacgc cagagcccca gatggatcct 6150

 gggattcaga acctcaaaaa gtgatcaagt taggcgtcct accagttaga 6200

 agtctactca tgatggaaga cacgttgtgg gcggcttccg gaggtcaagt 6250

 cttcatcatc agtgtggaga ctcatgctgt agagggtcag ctggaggccc 6300

 accaggagga aggcatggtg atctcccaca tggccgtgtc cggcgtcggg 6350

 atctggattg ccttcacctc agggtccacg ctccgccttt ttcacacgga 6400

 aactctcaag cacctgcagg acatcaacat cgccacccct gttcacaaca 6450

 tgctgccagg gcaccagcgg ctgtcggtga cgagcctgct cgtctgccac 6500

 ggattgctga tggtcggcac cagcctggga gtcctcgtgg ccctgccggt 6550

 cccacgtctg caagggattc ccaaagtgac cggaagaggc atggtctcct 6600

 accatgcaca caacagtcct gtcaaattca tcgtcctggc cacggctctg 6650

 cacgagaaag acaaggacaa atccagggac agcctggctc ctggccccga 6700

 gcctcaggac gaagaccaga aggacgcact tccgagtgga ggagctggtt 6750

 catctctgag ccagggtgac cctgacgcag ccatctggtt gggagattcg 6800

 ctgggatcga tgactcagaa aagcgacctg tcctcctcat ctgggtccct 6850

 gagcttgtct cacggctcca gctctctaga gcacagatca gaggacagca 6900

 ccatctatga tctcctgaag gatcctgtct cgctgagaag caaagcacgc 6950

 cgggccaaga aagccaaggc cagctcggcg ctggtggtct gtggagggca 7000

 gggccaccgc cgggtgcaca ggaaggcccg gcagccccac caggaagagc 7050

 tggcgccgac cgtcatggtc tggcagatcc ctctgctgaa tatataagca 7100

 ggacggccgc cttctgctgt cagaatttgc aatcaagggt gacttctcag 7150

 ctaatcctac agcctgagtg gttaagctgt gtctacactg gttgggaata 7200

 aattaaaaac agtatttggg ggagaaacgt gcaatagcgt aatggtggtg 7250

 tccctgccaa ttccttcctt ctcttctgta cagcagaagt aattacaagc 7300

 acttctcacg aaggcagaag actgatgcaa ttttcgagta attgagtgca 7350

 gttctgggaa aataccacat tctttttgac tgctgtagtc catatatgaa 7400

 tactaaatgt taaacttcat cagcgtcaga cctattgtat catattagag 7450

 aatttgcaga ctaagaattt atgagaaaat atatgtattc agtagtgcag 7500

 gcatttatta acaattctta aaagttttac ctgattcaga ttcacgactt 7550

 ttatttatat tctatatttt tgaatttcag agtaaaattt gttaacaatt 7600

 ttaaaagcca ggtaacacct accagtccag ttagcatgat ttgctttcag 7650

 aagtgagctg ggttttccaa agtggtataa tgtgtgtact gtatatttta 7700

 acaaagtaat atttttgtat tgcatttttc tattaaaaaa ttaacagtta 7750

 atgtttcagt caatgtatta tctgtagcat ttcacaaata atgtttgctt 7800

 tgaaccaaaa tgctcagtgc ctatcaacat ttggactcaa gcatcaacac 7850

 caaattattc ctcccttctc gtataaatag agtgactatc cacaggagaa 7900

 aagtgtgtgc tttagtatta gaggagatag gcagagaagt cttgcttagt 7950

 tccttcgtgc agcttcttgc ccctgttgac gtggaatgct gtgtctgctt 8000

 tagcacgcac gctccgaatg actcctggtg ctaggccatg ctggctgctg 8050

 tcactgagcg ggactcaggc caagaggcgt gacctcgggc cagcctgtct 8100

 gttgtgcaga cgcctcctct gcagaacgca tcagtttcta ttctgcagtt 8150

 gcagagccag ccccgcgtga gaacgtgcat aatgagtgca caccatcatg 8200

 tcaaggtgca tacttagtga gcgccatcct gctgaacgtg tatttcagtg 8250

 tttcacttac tggacggata acaagaaaaa aatcctaaca caggcagtca 8300

 ccagaaataa atgtctcagc actttacaga tgactaaaaa tgttaatttt 8350

 atgacttagc caaatatgtt ctaggttgca tatatccccc atgtgaaagt 8400

 gatttcttcc caagcttctc aaactgttag ctgctgtctg acttcatcaa 8450

 taaagtattt ttatttt 8467

<210> 2996
<211> 1121
<212> PRT
<213> Homo sapien

<400> 2996
 Met His Ser Asp Glu Met Ile Tyr Asp Asp Val Glu Asn Gly Asp
   1               5                  10                  15

 Glu Gly Gly Asn Ser Ser Leu Glu Tyr Gly Trp Ser Ser Ser Glu
                  20                  25                  30

 Phe Glu Ser Tyr Glu Glu Gln Ser Asp Ser Glu Cys Lys Asn Gly
                  35                  40                  45

 Ile Pro Arg Ser Phe Leu Arg Ser Asn His Lys Lys Gln Leu Ser
                  50                  55                  60

 His Asp Leu Thr Arg Leu Lys Glu His Tyr Glu Lys Lys Met Arg
                  65                  70                  75

 Asp Leu Met Ala Ser Thr Val Gly Val Val Glu Ile Gln Gln Leu
                  80                  85                  90

 Arg Gln Lys His Glu Leu Lys Met Gln Lys Leu Val Lys Ala Ala
                  95                 100                 105

 Lys Asp Gly Thr Lys Asp Gly Leu Glu Arg Thr Arg Ala Ala Val
                 110                 115                 120

 Lys Arg Gly Arg Ser Phe Ile Arg Thr Lys Ser Leu Ile Ala Gln
                 125                 130                 135

 Asp His Arg Ser Ser Leu Glu Glu Glu Gln Asn Leu Phe Ile Asp
                 140                 145                 150

 Val Asp Cys Lys His Pro Glu Ala Ile Leu Thr Pro Met Pro Glu
                 155                 160                 165

 Gly Leu Ser Gln Gln Gln Val Val Arg Arg Tyr Ile Leu Gly Ser
                 170                 175                 180

 Val Val Asp Ser Glu Lys Asn Tyr Val Asp Ala Leu Lys Arg Ile
                 185                 190                 195

 Leu Glu Gln Tyr Glu Lys Pro Leu Ser Glu Met Glu Pro Lys Val
                 200                 205                 210

 Leu Ser Glu Arg Lys Leu Lys Thr Val Phe Tyr Arg Val Lys Glu
                 215                 220                 225

 Ile Leu Gln Cys His Ser Leu Phe Gln Ile Ala Leu Ala Ser Arg
                 230                 235                 240

 Val Ser Glu Trp Asp Ser Val Glu Met Ile Gly Asp Val Phe Val
                 245                 250                 255

 Ala Ser Phe Ser Lys Ser Met Val Leu Asp Ala Tyr Ser Glu Tyr
                 260                 265                 270

 Val Asn Asn Phe Ser Thr Ala Val Ala Val Leu Lys Lys Thr Cys
                 275                 280                 285

 Ala Thr Lys Pro Ala Phe Leu Glu Phe Leu Lys Gln Glu Gln Glu
                 290                 295                 300

 Ala Ser Pro Asp Arg Thr Thr Leu Tyr Ser Leu Met Met Lys Pro
                 305                 310                 315

 Ile Gln Arg Phe Pro Gln Phe Ile Leu Leu Leu Gln Asp Met Leu
                 320                 325                 330

 Lys Asn Thr Ser Lys Gly His Pro Asp Arg Leu Pro Leu Gln Met
                 335                 340                 345

 Ala Leu Thr Glu Leu Glu Thr Leu Ala Glu Lys Leu Asn Glu Arg
                 350                 355                 360

 Lys Arg Asp Ala Asp Gln Arg Cys Glu Val Lys Gln Ile Ala Lys
                 365                 370                 375

 Ala Ile Asn Glu Arg Tyr Leu Asn Lys Leu Leu Ser Ser Gly Ser
                 380                 385                 390

 Arg Tyr Leu Ile Arg Ser Asp Asp Met Ile Glu Thr Val Tyr Asn
                 395                 400                 405

 Asp Arg Gly Glu Ile Val Lys Thr Lys Glu Arg Arg Val Phe Met
                 410                 415                 420

 Leu Asn Asp Val Leu Met Cys Ala Thr Val Ser Ser Arg Pro Ser
                 425                 430                 435

 His Asp Ser Arg Val Met Ser Ser Gln Arg Tyr Leu Leu Lys Trp
                 440                 445                 450

 Ser Val Pro Leu Gly His Val Asp Ala Ile Glu Tyr Gly Ser Ser
                 455                 460                 465

 Ala Gly Thr Gly Glu His Ser Arg His Leu Ala Val His Pro Pro
                 470                 475                 480

 Glu Ser Leu Ala Val Val Ala Asn Ala Lys Pro Asn Lys Val Tyr
                 485                 490                 495

 Met Gly Pro Gly Gln Leu Tyr Gln Asp Leu Gln Asn Leu Leu His
                 500                 505                 510

 Asp Leu Asn Val Ile Gly Gln Ile Thr Gln Leu Ile Gly Asn Leu
                 515                 520                 525

 Lys Gly Asn Tyr Gln Asn Leu Asn Gln Ser Val Ala His Asp Trp
                 530                 535                 540

 Thr Ser Gly Leu Gln Arg Leu Ile Leu Lys Lys Glu Asp Glu Ile
                 545                 550                 555

 Arg Ala Ala Asp Cys Cys Arg Ile Gln Leu Gln Leu Pro Gly Lys
                 560                 565                 570

 Gln Asp Lys Ser Gly Arg Pro Thr Phe Phe Thr Ala Val Phe Asn
                 575                 580                 585

 Thr Phe Thr Pro Ala Ile Lys Glu Ser Trp Val Asn Ser Leu Gln
                 590                 595                 600

 Met Ala Lys Leu Ala Leu Glu Glu Glu Asn His Met Gly Trp Phe
                 605                 610                 615

 Cys Val Glu Asp Asp Gly Asn His Ile Lys Lys Glu Lys His Pro
                 620                 625                 630

 Leu Leu Val Gly His Met Pro Val Met Val Ala Lys Gln Gln Glu
                 635                 640                 645

 Phe Lys Ile Glu Cys Ala Ala Tyr Asn Pro Glu Pro Tyr Leu Asn
                 650                 655                 660

 Asn Glu Ser Gln Pro Asp Ser Phe Ser Thr Ala His Gly Phe Leu
                 665                 670                 675

 Trp Ile Gly Ser Cys Thr His Gln Met Gly Gln Ile Ala Ile Val
                 680                 685                 690

 Ser Phe Gln Asn Ser Thr Pro Lys Val Ile Glu Cys Phe Asn Val
                 695                 700                 705

 Glu Ser Arg Ile Leu Cys Met Leu Tyr Val Pro Val Glu Glu Lys
                 710                 715                 720

 Arg Arg Glu Pro Gly Ala Pro Pro Asp Pro Glu Thr Pro Ala Val
                 725                 730                 735

 Arg Ala Ser Asp Val Pro Thr Ile Cys Val Gly Thr Glu Glu Gly
                 740                 745                 750

 Ser Ile Ser Ile Tyr Lys Ser Ser Gln Gly Ser Lys Lys Val Arg
                 755                 760                 765

 Leu Gln His Phe Phe Thr Pro Glu Lys Ser Thr Val Met Ser Leu
                 770                 775                 780

 Ala Cys Thr Ser Gln Ser Leu Tyr Ala Gly Leu Val Asn Gly Ala
                 785                 790                 795

 Val Ala Ser Tyr Ala Arg Ala Pro Asp Gly Ser Trp Asp Ser Glu
                 800                 805                 810

 Pro Gln Lys Val Ile Lys Leu Gly Val Leu Pro Val Arg Ser Leu
                 815                 820                 825

 Leu Met Met Glu Asp Thr Leu Trp Ala Ala Ser Gly Gly Gln Val
                 830                 835                 840

 Phe Ile Ile Ser Val Glu Thr His Ala Val Glu Gly Gln Leu Glu
                 845                 850                 855

 Ala His Gln Glu Glu Gly Met Val Ile Ser His Met Ala Val Ser
                 860                 865                 870

 Gly Val Gly Ile Trp Ile Ala Phe Thr Ser Gly Ser Thr Leu Arg
                 875                 880                 885

 Leu Phe His Thr Glu Thr Leu Lys His Leu Gln Asp Ile Asn Ile
                 890                 895                 900

 Ala Thr Pro Val His Asn Met Leu Pro Gly His Gln Arg Leu Ser
                 905                 910                 915

 Val Thr Ser Leu Leu Val Cys His Gly Leu Leu Met Val Gly Thr
                 920                 925                 930

 Ser Leu Gly Val Leu Val Ala Leu Pro Val Pro Arg Leu Gln Gly
                 935                 940                 945

 Ile Pro Lys Val Thr Gly Arg Gly Met Val Ser Tyr His Ala His
                 950                 955                 960

 Asn Ser Pro Val Lys Phe Ile Val Leu Ala Thr Ala Leu His Glu
                 965                 970                 975

 Lys Asp Lys Asp Lys Ser Arg Asp Ser Leu Ala Pro Gly Pro Glu
                 980                 985                 990

 Pro Gln Asp Glu Asp Gln Lys Asp Ala Leu Pro Ser Gly Gly Ala
                 995                1000                1005

 Gly Ser Ser Leu Ser Gln Gly Asp Pro Asp Ala Ala Ile Trp Leu
                1010                1015                1020

 Gly Asp Ser Leu Gly Ser Met Thr Gln Lys Ser Asp Leu Ser Ser
                1025                1030                1035

 Ser Ser Gly Ser Leu Ser Leu Ser His Gly Ser Ser Ser Leu Glu
                1040                1045                1050

 His Arg Ser Glu Asp Ser Thr Ile Tyr Asp Leu Leu Lys Asp Pro
                1055                1060                1065

 Val Ser Leu Arg Ser Lys Ala Arg Arg Ala Lys Lys Ala Lys Ala
                1070                1075                1080

 Ser Ser Ala Leu Val Val Cys Gly Gly Gln Gly His Arg Arg Val
                1085                1090                1095

 His Arg Lys Ala Arg Gln Pro His Gln Glu Glu Leu Ala Pro Thr
                1100                1105                1110

 Val Met Val Trp Gln Ile Pro Leu Leu Asn Ile
                1115                1120

<210> 2997
<211> 1497
<212> DNA
<213> Homo sapien

<400> 2997
 accgctggcc ccagggaaag ccgagcggcc accgagccgg cagagaccca 50

 ccgagcggcg gcggagggag cagcgccggg gcgcacgagg gcaccatggc 100

 ccagacgccc gccttcgaca agcccaaagt agaactgcat gtccacctag 150

 acggatccat caagcctgaa accatcttat actatggcag gaggagaggg 200

 atcgccctcc cagctaacac agcagagggg ctgctgaacg tcattggcat 250

 ggacaagccg ctcacccttc cagacttcct ggccaaattt gactactaca 300

 tgcctgctat cgcgggctgc cgggaggcta tcaaaaggat cgcctatgag 350

 tttgtagaga tgaaggccaa agagggcgtg gtgtatgtgg aggtgcggta 400

 cagtccgcac ctgctggcca actccaaagt ggagccaatc ccctggaacc 450

 aggctgaagg ggacctcacc ccagacgagg tggtggccct agtgggccag 500

 ggcctgcagg agggggagcg agacttcggg gtcaaggccc ggtccatcct 550

 gtgctgcatg cgccaccagc ccaactggtc ccccaaggtg gtggagctgt 600

 gtaagaacta ccagcagcag accgtggtag ccattgacct ggctggagat 650

 gagaccatcc caggaagcag cctcttgcct ggacatgtcc aggcctacca 700

 ggaggctgtg aagagcggca ttcaccgtac tgtccacgcc ggggaggtgg 750

 gctcggccga agtagtaaaa gaggctgtgg acatactcaa gacagagcgg 800

 ctgggacacg gctaccacac cctggaagac caggcccttt ataacaggct 850

 gcggcaggaa aacatgcact tcgagatctg cccctggtcc agctacctca 900

 ctggtgcctg gaagccggac acggagcatg cagtcattcg gctcaaaaat 950

 gaccaggcta actactcgct caacacagat gacccgctca tcttcaagtc 1000

 caccctggac actgattacc agatgaccaa acgggacatg ggctttactg 1050

 aagaggagtt taaaaggctg aacatcaatg cggccaaatc tagtttcctc 1100

 ccagaagatg aaaagaggga gcttctcgac ctgctctata aagcctatgg 1150

 gatgccacct tcagcctctg cagggcagaa cctctgaaga cgccactcct 1200

 ccaagccttc accctgtgga gtcaccccaa ctctgtgggg ctgagcaaca 1250

 tttttacatt tattccttcc aagaagacca tgatctcaat agtcagttac 1300

 tgatgctcct gaaccctatg tgtccatttc tgcacacacg tatacctcgg 1350

 catggccgcg tcacttctct gattatgtgc cctggcaggg accagcgccc 1400

 ttgcacatgg gcatggttga atctgaaacc ctccttctgt ggcaacttgt 1450

 actgaaaatc tggtgctcaa taaagaagcc catggctggt ggcatgc 1497

<210> 2998
<211> 363
<212> PRT
<213> Homo sapien

<400> 2998
 Met Ala Gln Thr Pro Ala Phe Asp Lys Pro Lys Val Glu Leu His
   1               5                  10                  15

 Val His Leu Asp Gly Ser Ile Lys Pro Glu Thr Ile Leu Tyr Tyr
                  20                  25                  30

 Gly Arg Arg Arg Gly Ile Ala Leu Pro Ala Asn Thr Ala Glu Gly
                  35                  40                  45

 Leu Leu Asn Val Ile Gly Met Asp Lys Pro Leu Thr Leu Pro Asp
                  50                  55                  60

 Phe Leu Ala Lys Phe Asp Tyr Tyr Met Pro Ala Ile Ala Gly Cys
                  65                  70                  75

 Arg Glu Ala Ile Lys Arg Ile Ala Tyr Glu Phe Val Glu Met Lys
                  80                  85                  90

 Ala Lys Glu Gly Val Val Tyr Val Glu Val Arg Tyr Ser Pro His
                  95                 100                 105

 Leu Leu Ala Asn Ser Lys Val Glu Pro Ile Pro Trp Asn Gln Ala
                 110                 115                 120

 Glu Gly Asp Leu Thr Pro Asp Glu Val Val Ala Leu Val Gly Gln
                 125                 130                 135

 Gly Leu Gln Glu Gly Glu Arg Asp Phe Gly Val Lys Ala Arg Ser
                 140                 145                 150

 Ile Leu Cys Cys Met Arg His Gln Pro Asn Trp Ser Pro Lys Val
                 155                 160                 165

 Val Glu Leu Cys Lys Asn Tyr Gln Gln Gln Thr Val Val Ala Ile
                 170                 175                 180

 Asp Leu Ala Gly Asp Glu Thr Ile Pro Gly Ser Ser Leu Leu Pro
                 185                 190                 195

 Gly His Val Gln Ala Tyr Gln Glu Ala Val Lys Ser Gly Ile His
                 200                 205                 210

 Arg Thr Val His Ala Gly Glu Val Gly Ser Ala Glu Val Val Lys
                 215                 220                 225

 Glu Ala Val Asp Ile Leu Lys Thr Glu Arg Leu Gly His Gly Tyr
                 230                 235                 240

 His Thr Leu Glu Asp Gln Ala Leu Tyr Asn Arg Leu Arg Gln Glu
                 245                 250                 255

 Asn Met His Phe Glu Ile Cys Pro Trp Ser Ser Tyr Leu Thr Gly
                 260                 265                 270

 Ala Trp Lys Pro Asp Thr Glu His Ala Val Ile Arg Leu Lys Asn
                 275                 280                 285

 Asp Gln Ala Asn Tyr Ser Leu Asn Thr Asp Asp Pro Leu Ile Phe
                 290                 295                 300

 Lys Ser Thr Leu Asp Thr Asp Tyr Gln Met Thr Lys Arg Asp Met
                 305                 310                 315

 Gly Phe Thr Glu Glu Glu Phe Lys Arg Leu Asn Ile Asn Ala Ala
                 320                 325                 330

 Lys Ser Ser Phe Leu Pro Glu Asp Glu Lys Arg Glu Leu Leu Asp
                 335                 340                 345

 Leu Leu Tyr Lys Ala Tyr Gly Met Pro Pro Ser Ala Ser Ala Gly
                 350                 355                 360

 Gln Asn Leu


<210> 2999
<211> 2871
<212> DNA
<213> Homo sapien

<400> 2999
 gccccgcgcc gcgccggacc cgagcatatt tcattttctg tcattggact 50

 ttgagccatt agaaccatga gcaactacag tgtgtcactg gttggcccag 100

 ctccttgggg tttccggctg cagggcggta aggatttcaa catgcctctg 150

 acaatctcta gtctaaaaga tggcggcaag gcagcccagg caaatgtaag 200

 aataggcgat gtggttctca gcattgatgg aataaatgca caaggaatga 250

 ctcatcttga agcccagaat aagattaagg gttgtacagg ctctttgaat 300

 atgactctgc aaagagcatc tgctgcaccc aagcctgagc cggttcctgt 350

 tcaaaagccc accaagaaaa cacattgtgg agcgctatac agagttttat 400

 catgtaccca ctcacagtga tgccagcaag aagagactga ttgaggatac 450

 tgaagactgg cgtccaagga ctggaacaac tcagtctcgc tctttccgaa 500

 tccttgccca gatcactggg actgaacatt tgaaagaatc tgaagccgat 550

 aatacaaaga aggcaaataa ctctcaggag ccttctccgc agttggcttc 600

 ctcggtagct tccacacgga gcatgcccga gagcctggac agcccaacct 650

 ctggcagacc aggggttacc agcctcacaa ctgcagctgc cttcaagcct 700

 gtaggatcca ctggcgtcat caagtcacca agctggcaac ggccaaacca 750

 aggagtacct tccactggaa gaatctcaaa cagcgctgct tactcaggat 800

 cagtggcacc agccaactca gctttgggac aaacccagcc aagtgaccag 850

 gacactttag tgcaaagagc tgagcacatt ccagcaggga aacgaactcc 900

 gatgtgcgcc cattgtaacc aggtcatcag aggaccattc ttagtggcac 950

 tggggaaatc ttggcaccca gaagaattca actgcgctca ctgcaaaaat 1000

 acaatggcct acattggatt tgtagaggag aaaggagccc tgtattgtga 1050

 gctgtgctat gagaaattct ttgcccctga atgtggtcga tgccaaagga 1100

 agatccttgg agaagtcatc aatgcgttga aacaaacttg gcatgtttcc 1150

 tgttttgtgt gtgtagcctg tggaaagccc attcggaaca atgtttttca 1200

 cttggaggat ggtgaaccct actgtgagac tgattattat gccctctttg 1250

 gtactatatg ccatggatgt gaatttccca tagaagctgg tgacatgttc 1300

 ctggaagctc tgggctacac ctggcatgac acttgctttg tatgctcagt 1350

 gtgttgtgaa agtttggaag gtcagacctt tttctccaag aaggacaagc 1400

 ccctgtgtaa gaaacatgct cattctgtga atttttgaaa gtcaacagtt 1450

 caggagaaga gaaggaattt gaagagaaaa aggaaaatta aaattactaa 1500

 ttaattttta gattcaatat ttatatggag ttttgaaaaa taatagtggc 1550

 cctgaaggaa taaattccag ctttaaaaac caagtctgag gaaatatttg 1600

 gcttcataaa gtaaagagac ggtttggcat ttattattac tttttcctgt 1650

 attttatgcc cataaaataa gctttataaa aaccaatttc ctgatggact 1700

 attaaattca tcttagaata aattagtgaa gaatttaatt ttagaataaa 1750

 taatccaatc tgaaataatt ataccttctt tccttgttag gtagttatga 1800

 gtaaatctgc aaaaggcaat gaaaatgcct taaattttat caataacaga 1850

 attattgtat ttaaaaaaaa actaatactt atctttaaaa tagtaaatag 1900

 gattttaaac agagaatttt atcagtaata ggtgtcagtt tttaaaaaat 1950

 tgcttgtagg ctgagcgcgg tggctcacgc ctgtaatccc agcactttgg 2000

 gaggccaagg tgggtggacc acatgaggtc aggagtttga gatcagcctg 2050

 gccaacatgg tgaaacccca tctctactaa aaatacaaaa attagccgga 2100

 cgcagtggca cgcgcctgta atcccagcta ctcaagaggc tgaggcacga 2150

 gaatcacttg aacccgggag ggagaggttg cagtgagcca agatcgtacc 2200

 actgcactcc agcctgggtg acagagtgag actctgtctc caaaaaaaac 2250

 tttgcttgta tattattttt gccttacagt ggatcattct agtaggaaag 2300

 gacaataaga ttttttatca aaatgtgtca tgccagtaag agatgttata 2350

 ttcttttctc atttcttccc cacccaaaaa taagctacca tatagcttat 2400

 aagtctcaaa tttttgcctt ttactaaaat gtgattgttt ctattcattg 2450

 tgtatgcttc atcacctata ttaggcaaat tccatttttt tcccttgtgc 2500

 taaggtaaag atttaattaa ataattttgg cctctcatag ttttctctct 2550

 ctttaaagag aataaataga gggccaggtg tggtggctca cgcctgtgat 2600

 cccagcactt tgggaggcca agacgggcgg atcatgaggt caagagatca 2650

 agatcatcct ggccaacatg gtgaaaccct gtctctacta aaaatacaaa 2700

 aatgagctgg gcatggtggg gcgtgcctgt agtcccatgt acttgggagg 2750

 ctgaggcagg aaaattcttg aacccaggag acggaagttg cagtgagctg 2800

 agatcacacc actgcactcc agcctggtga cagagcaaga ctccggctct 2850

 taaaaaaaaa aaaaaaaaaa a 2871

<210> 3000
<211> 456
<212> PRT
<213> Homo sapien

<400> 3000
 Met Ser Asn Tyr Ser Val Ser Leu Val Gly Pro Ala Pro Trp Gly
   1               5                  10                  15

 Phe Arg Leu Gln Gly Gly Lys Asp Phe Asn Met Pro Leu Thr Ile
                  20                  25                  30

 Ser Ser Leu Lys Asp Gly Gly Lys Ala Ala Gln Ala Asn Val Arg
                  35                  40                  45

 Ile Gly Asp Val Val Leu Ser Ile Asp Gly Ile Asn Ala Gln Gly
                  50                  55                  60

 Met Thr His Leu Glu Ala Gln Asn Lys Ile Lys Gly Cys Thr Gly
                  65                  70                  75

 Ser Leu Asn Met Thr Leu Gln Arg Ala Ser Ala Ala Pro Lys Pro
                  80                  85                  90

 Glu Pro Val Pro Val Gln Lys Pro Thr Lys Lys Thr His Cys Gly
                  95                 100                 105

 Ala Leu Tyr Arg Val Leu Ser Cys Thr His Ser Gln Asp Ala Ser
                 110                 115                 120

 Lys Lys Arg Leu Ile Glu Asp Thr Glu Asp Trp Arg Pro Arg Thr
                 125                 130                 135

 Gly Thr Thr Gln Ser Arg Ser Phe Arg Ile Leu Ala Gln Ile Thr
                 140                 145                 150

 Gly Thr Glu His Leu Lys Glu Ser Glu Ala Asp Asn Thr Lys Lys
                 155                 160                 165

 Ala Asn Asn Ser Gln Glu Pro Ser Pro Gln Leu Ala Ser Ser Val
                 170                 175                 180

 Ala Ser Thr Arg Ser Met Pro Glu Ser Leu Asp Ser Pro Thr Ser
                 185                 190                 195

 Gly Arg Pro Gly Val Thr Ser Leu Thr Thr Ala Ala Ala Phe Lys
                 200                 205                 210

 Pro Val Gly Ser Thr Gly Val Ile Lys Ser Pro Ser Trp Gln Arg
                 215                 220                 225

 Pro Asn Gln Gly Val Pro Ser Thr Gly Arg Ile Ser Asn Ser Ala
                 230                 235                 240

 Ala Tyr Ser Gly Ser Val Ala Pro Ala Asn Ser Ala Leu Gly Gln
                 245                 250                 255

 Thr Gln Pro Ser Asp Gln Asp Thr Leu Val Gln Arg Ala Glu His
                 260                 265                 270

 Ile Pro Ala Gly Lys Arg Thr Pro Met Cys Ala His Cys Asn Gln
                 275                 280                 285

 Val Ile Arg Gly Pro Phe Leu Val Ala Leu Gly Lys Ser Trp His
                 290                 295                 300

 Pro Glu Glu Phe Asn Cys Ala His Cys Lys Asn Thr Met Ala Tyr
                 305                 310                 315

 Ile Gly Phe Val Glu Glu Lys Gly Ala Leu Tyr Cys Glu Leu Cys
                 320                 325                 330

 Tyr Glu Lys Phe Phe Ala Pro Glu Cys Gly Arg Cys Gln Arg Lys
                 335                 340                 345

 Ile Leu Gly Glu Val Ile Asn Ala Leu Lys Gln Thr Trp His Val
                 350                 355                 360

 Ser Cys Phe Val Cys Val Ala Cys Gly Lys Pro Ile Arg Asn Asn
                 365                 370                 375

 Val Phe His Leu Glu Asp Gly Glu Pro Tyr Cys Glu Thr Asp Tyr
                 380                 385                 390

 Tyr Ala Leu Phe Gly Thr Ile Cys His Gly Cys Glu Phe Pro Ile
                 395                 400                 405

 Glu Ala Gly Asp Met Phe Leu Glu Ala Leu Gly Tyr Thr Trp His
                 410                 415                 420

 Asp Thr Cys Phe Val Cys Ser Val Cys Cys Glu Ser Leu Glu Gly
                 425                 430                 435

 Gln Thr Phe Phe Ser Lys Lys Asp Lys Pro Leu Cys Lys Lys His
                 440                 445                 450

 Ala His Ser Val Asn Phe
                 455

<210> 3001
<211> 1379
<212> DNA
<213> Homo sapien

<400> 3001
 gcgcgcagca gccatctcca ctccaaagtt agacaaaatg ccaggaatgt 50

 tcttctctgc taacccaaag gaattgaaag gaaccactca ttcacttcta 100

 gacgacaaaa tgcaaaaaag gaggccaaag acttttggaa tggatatgaa 150

 agcatacctg agatctatga tcccacatct ggaatctgga atgaaatctt 200

 ccaagtccaa ggatgtactt tctgctgctg aagtaatgca atggtctcaa 250

 tctctggaaa aacttcttgc caaccaaact ggtcaaaatg tctttggaag 300

 tttcctaaag tctgaattca gtgaggagaa tattgagttc tggctggctt 350

 gtgaagacta taagaaaaca gagtctgatc ttttgccctg taaagcagaa 400

 gagatatata aagcatttgt gcattcagat gctgctaaac aaatcaatat 450

 tgacttccgc actcgagaat ctacagccaa gaagattaaa gcaccaaccc 500

 ccacgtgttt tgatgaagca caaaaagtca tatatactct tatggaaaag 550

 gactcttatc ccaggttcct caaatcagat atttacttaa atcttctaaa 600

 tgacctgcag gctaatagcc taaagtgact ggtccctggc tgaagggaat 650

 taacagatag tatcaagcgc agaaggaatg tgccagtatg gctccctggg 700

 tgaacagctt ggccttttgt gggtgtcttg acagcccaag aagaacaaat 750

 gactcagaat ggattaacat gaaagttatc caggcgcaga gttgaagaag 800

 cataagcaag acaaaaacag agagaccgca gaaggaggaa gatactgtgg 850

 tactgtcata aaaaacagtg gagctctgta ttagaaagcc cctcagaact 900

 gggaaggcca ggtaactcta gttacacaga aactgtgact aaagtctatg 950

 aaactgatta caacagactg taagaatcaa agtcaactga catctatgct 1000

 acatattatt atatagtttg tactgagcta ttgaagtccc attaacttaa 1050

 agtatatgtt ttcaaattgc cattgctact attgcttgtc ggtgttattt 1100

 tattttattg tttttgactt tggaagagat gaactgtgta tttaacttaa 1150

 gctattgctc ttaaaaccag ggagtcagaa tatatttgta agttaaatca 1200

 ttggtgctaa taataaatgt ggattttgta ttaaaatata tagaagcaat 1250

 ttctgtttac atgtccttgc tacttttaaa aacttgcatt tattcctcag 1300

 attttaaaaa taaataaata attcatttaa aaaaaaaaaa aaaaaaaaaa 1350

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1379

<210> 3002
<211> 196
<212> PRT
<213> Homo sapien

<400> 3002
 Met Pro Gly Met Phe Phe Ser Ala Asn Pro Lys Glu Leu Lys Gly
   1               5                  10                  15

 Thr Thr His Ser Leu Leu Asp Asp Lys Met Gln Lys Arg Arg Pro
                  20                  25                  30

 Lys Thr Phe Gly Met Asp Met Lys Ala Tyr Leu Arg Ser Met Ile
                  35                  40                  45

 Pro His Leu Glu Ser Gly Met Lys Ser Ser Lys Ser Lys Asp Val
                  50                  55                  60

 Leu Ser Ala Ala Glu Val Met Gln Trp Ser Gln Ser Leu Glu Lys
                  65                  70                  75

 Leu Leu Ala Asn Gln Thr Gly Gln Asn Val Phe Gly Ser Phe Leu
                  80                  85                  90

 Lys Ser Glu Phe Ser Glu Glu Asn Ile Glu Phe Trp Leu Ala Cys
                  95                 100                 105

 Glu Asp Tyr Lys Lys Thr Glu Ser Asp Leu Leu Pro Cys Lys Ala
                 110                 115                 120

 Glu Glu Ile Tyr Lys Ala Phe Val His Ser Asp Ala Ala Lys Gln
                 125                 130                 135

 Ile Asn Ile Asp Phe Arg Thr Arg Glu Ser Thr Ala Lys Lys Ile
                 140                 145                 150

 Lys Ala Pro Thr Pro Thr Cys Phe Asp Glu Ala Gln Lys Val Ile
                 155                 160                 165

 Tyr Thr Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Lys Ser
                 170                 175                 180

 Asp Ile Tyr Leu Asn Leu Leu Asn Asp Leu Gln Ala Asn Ser Leu
                 185                 190                 195

 Lys


<210> 3003
<211> 1026
<212> DNA
<213> Homo sapien

<400> 3003
 cagcatgttg agccgggcag tgtgcggcac cagcaggcag ctgcctccgg 50

 ttttggggta tctgggctcc aggcagaagc acagcctccc cgacctgccc 100

 tacgactacg gcgccctgga acctcacatc aacgcgcaga tcatgcagct 150

 gcaccacagc aagcaccacg cggcctacgt gaacaacctg aacgtcaccg 200

 aggagaagta ccaggaggcg ttggccaagg gagatgttac agcccagata 250

 gctcttcagc ctgcactgaa gttcaatggt ggtggtcata tcaatcatag 300

 cattttctgg acaaacctca gccctaacgg tggtggagaa cccaaagggg 350

 agttgctgga agccatcaaa ctggactttg gttcctttga caagtttaag 400

 gagaagctga cggctgcatc tgttggtgtc caaggctcag gttggggttg 450

 gcttggtttc aataaggaac ggggacactt acaaattgct gcttgtccaa 500

 atcaggatcc actgcaagga acaacaggcc ttattccact gctggggatt 550

 gatgtgtggg agcacgctta ctaccttcag tataaaaatg tcaggcctga 600

 ttatctaaaa gctatttgga atgtaatcaa ctgggagaat gtaactgaaa 650

 gatacatggc ttgcaaaaag taaaccacga tcgttatgct gagtatgtta 700

 agctctttat gactgttttt gtagtggtat agagtactgc agaatacagt 750

 aagctgctct attgtagcat ttcttgatgt tgcttagtca cttatttcat 800

 aaacaactta atgttctgaa taatttctta ctaaacattt tgttattggg 850

 caagtgattg aaaatagtaa atgctttgtg tgattgaatc tgattggaca 900

 ttttcttcag agagctaaat tacaattgtc atttataaaa ccatcaaaaa 950

 tattccatcc atatactttg gggacttgta gggatgcctt tctagtccta 1000

 ttctattgca gttatagaaa atctag 1026

<210> 3004
<211> 222
<212> PRT
<213> Homo sapien

<400> 3004
 Met Leu Ser Arg Ala Val Cys Gly Thr Ser Arg Gln Leu Pro Pro
   1               5                  10                  15

 Val Leu Gly Tyr Leu Gly Ser Arg Gln Lys His Ser Leu Pro Asp
                  20                  25                  30

 Leu Pro Tyr Asp Tyr Gly Ala Leu Glu Pro His Ile Asn Ala Gln
                  35                  40                  45

 Ile Met Gln Leu His His Ser Lys His His Ala Ala Tyr Val Asn
                  50                  55                  60

 Asn Leu Asn Val Thr Glu Glu Lys Tyr Gln Glu Ala Leu Ala Lys
                  65                  70                  75

 Gly Asp Val Thr Ala Gln Ile Ala Leu Gln Pro Ala Leu Lys Phe
                  80                  85                  90

 Asn Gly Gly Gly His Ile Asn His Ser Ile Phe Trp Thr Asn Leu
                  95                 100                 105

 Ser Pro Asn Gly Gly Gly Glu Pro Lys Gly Glu Leu Leu Glu Ala
                 110                 115                 120

 Ile Lys Leu Asp Phe Gly Ser Phe Asp Lys Phe Lys Glu Lys Leu
                 125                 130                 135

 Thr Ala Ala Ser Val Gly Val Gln Gly Ser Gly Trp Gly Trp Leu
                 140                 145                 150

 Gly Phe Asn Lys Glu Arg Gly His Leu Gln Ile Ala Ala Cys Pro
                 155                 160                 165

 Asn Gln Asp Pro Leu Gln Gly Thr Thr Gly Leu Ile Pro Leu Leu
                 170                 175                 180

 Gly Ile Asp Val Trp Glu His Ala Tyr Tyr Leu Gln Tyr Lys Asn
                 185                 190                 195

 Val Arg Pro Asp Tyr Leu Lys Ala Ile Trp Asn Val Ile Asn Trp
                 200                 205                 210

 Glu Asn Val Thr Glu Arg Tyr Met Ala Cys Lys Lys
                 215                 220

<210> 3005
<211> 1743
<212> DNA
<213> Homo sapien

<400> 3005
 ccggcagcac catgtcgctc acggtcgtca gcatggcgtg cgttgggttc 50

 ttcttgctgc agggggcctg gccactcatg ggtggtcagg acaaaccctt 100

 cctgtctgcc cggcccagca ctgtggtgcc tcgaggagga cacgtggctc 150

 ttcagtgtca ctatcgtcgt gggtttaaca atttcatgct gtacaaagaa 200

 gacagaagcc acgttcccat cttccacggc agaatattcc aggagagctt 250

 catcatgggc cctgtgaccc cagcacatgc agggacctac agatgtcggg 300

 gttcacgccc acactccctc actgggtggt cggcacccag caaccccgtg 350

 gtgatcatgg tcacaggaaa ccacagaaaa ccttccctcc tggcccaccc 400

 agggcccctg ctgaaatcag gagagacagt catcctgcaa tgttggtcag 450

 atgtcatgtt tgagcacttc tttctgcaca gagaggggat ctctgaggac 500

 ccctcacgcc tcgttggaca gatccatgat ggggtctcca aggccaactt 550

 ctccatcggt cccttgatgc ctgtccttgc aggaacctac agatgttatg 600

 gttctgttcc tcactccccc tatcagttgt cagctcccag tgaccccctg 650

 gacatcgtga tcacaggtct atatgagaaa ccttctctct cagcccagcc 700

 gggccccacg gttcaggcag gagagaacgt gaccttgtcc tgtagctcct 750

 ggagctccta tgacatctac catctgtcca gggaagggga ggcccatgaa 800

 cgtaggctcc gtgcagtgcc caaggtcaac agaacattcc aggcagactt 850

 tcctctgggc cctgccaccc acggagggac ctacagatgc ttcggctctt 900

 tccgtgccct gccctgcgtg tggtcaaact caagtgaccc actgcttgtt 950

 tctgtcacag gaaacccttc aagtagttgg ccttcaccca cagaaccaag 1000

 ctccaaatct ggtatctgca gacacctgca tgttctgatt gggacctcag 1050

 tggtcatctt cctcttcatc ctcctcctct tctttctcct ttatcgctgg 1100

 tgctccaaca aaaagaatgc tgctgtaatg gaccaagagc ctgcggggga 1150

 cagaacagtg aataggcagg actctgatga acaagaccct caggaggtga 1200

 cgtacgcaca gttggatcac tgcgttttca tacagagaaa aatcagtcgc 1250

 ccttctcaga ggcccaagac acccctaaca gataccagcg tgtacacgga 1300

 acttccaaat gctgagccca gatccaaagt tgtctcctgc ccacgagcac 1350

 cacagtcagg tcttgagggg gttttctagg gagacaacag ccctgtctca 1400

 aaaccaggtt gccagatcca atgaaccagc agctggaatc tgaaggcatc 1450

 agtctgcatc ttaggggatc gctcttcctc acaccacgaa tctgaacatg 1500

 cctctctctt gcttacaaat gcctaaggtc gccactgcct gctgcagaga 1550

 aaacacactc ctttgcttag cccacaagta tctatttcac ttgacccctg 1600

 cccacctctc caacctaact ggcttacttc ctagtcctac ttgaggctgc 1650

 aatcacactg aggaactcac aattccaaac atacaagagg ctccctctta 1700

 acacggcact tacacacttg ctgttccacc ttccctcatg ctg 1743

<210> 3006
<211> 455
<212> PRT
<213> Homo sapien

<400> 3006
 Met Ser Leu Thr Val Val Ser Met Ala Cys Val Gly Phe Phe Leu
   1               5                  10                  15

 Leu Gln Gly Ala Trp Pro Leu Met Gly Gly Gln Asp Lys Pro Phe
                  20                  25                  30

 Leu Ser Ala Arg Pro Ser Thr Val Val Pro Arg Gly Gly His Val
                  35                  40                  45

 Ala Leu Gln Cys His Tyr Arg Arg Gly Phe Asn Asn Phe Met Leu
                  50                  55                  60

 Tyr Lys Glu Asp Arg Ser His Val Pro Ile Phe His Gly Arg Ile
                  65                  70                  75

 Phe Gln Glu Ser Phe Ile Met Gly Pro Val Thr Pro Ala His Ala
                  80                  85                  90

 Gly Thr Tyr Arg Cys Arg Gly Ser Arg Pro His Ser Leu Thr Gly
                  95                 100                 105

 Trp Ser Ala Pro Ser Asn Pro Val Val Ile Met Val Thr Gly Asn
                 110                 115                 120

 His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu Leu Lys
                 125                 130                 135

 Ser Gly Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Met Phe
                 140                 145                 150

 Glu His Phe Phe Leu His Arg Glu Gly Ile Ser Glu Asp Pro Ser
                 155                 160                 165

 Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe
                 170                 175                 180

 Ser Ile Gly Pro Leu Met Pro Val Leu Ala Gly Thr Tyr Arg Cys
                 185                 190                 195

 Tyr Gly Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser
                 200                 205                 210

 Asp Pro Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser
                 215                 220                 225

 Leu Ser Ala Gln Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val
                 230                 235                 240

 Thr Leu Ser Cys Ser Ser Trp Ser Ser Tyr Asp Ile Tyr His Leu
                 245                 250                 255

 Ser Arg Glu Gly Glu Ala His Glu Arg Arg Leu Arg Ala Val Pro
                 260                 265                 270

 Lys Val Asn Arg Thr Phe Gln Ala Asp Phe Pro Leu Gly Pro Ala
                 275                 280                 285

 Thr His Gly Gly Thr Tyr Arg Cys Phe Gly Ser Phe Arg Ala Leu
                 290                 295                 300

 Pro Cys Val Trp Ser Asn Ser Ser Asp Pro Leu Leu Val Ser Val
                 305                 310                 315

 Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser Pro Thr Glu Pro Ser
                 320                 325                 330

 Ser Lys Ser Gly Ile Cys Arg His Leu His Val Leu Ile Gly Thr
                 335                 340                 345

 Ser Val Val Ile Phe Leu Phe Ile Leu Leu Leu Phe Phe Leu Leu
                 350                 355                 360

 Tyr Arg Trp Cys Ser Asn Lys Lys Asn Ala Ala Val Met Asp Gln
                 365                 370                 375

 Glu Pro Ala Gly Asp Arg Thr Val Asn Arg Gln Asp Ser Asp Glu
                 380                 385                 390

 Gln Asp Pro Gln Glu Val Thr Tyr Ala Gln Leu Asp His Cys Val
                 395                 400                 405

 Phe Ile Gln Arg Lys Ile Ser Arg Pro Ser Gln Arg Pro Lys Thr
                 410                 415                 420

 Pro Leu Thr Asp Thr Ser Val Tyr Thr Glu Leu Pro Asn Ala Glu
                 425                 430                 435

 Pro Arg Ser Lys Val Val Ser Cys Pro Arg Ala Pro Gln Ser Gly
                 440                 445                 450

 Leu Glu Gly Val Phe
                 455

<210> 3007
<211> 1040
<212> DNA
<213> Homo sapien

<400> 3007
 cgacgagcca tggttgctgg gagcgacgcg gggcgggccc tgggggtcct 50

 cagcgtggtc tgcctgctgc actgctttgg tttcatcagc tgtttttccc 100

 aacaaatata tggtgttgtg tatgggaatg taactttcca tgtaccaagc 150

 aatgtgcctt taaaagaggt cctatggaaa aaacaaaagg ataaagttgc 200

 agaactggaa aattctgaat tcagagcttt ctcatctttt aaaaataggg 250

 tttatttaga cactgtgtca ggtagcctca ctatctacaa cttaacatca 300

 tcagatgaag atgagtatga aatggaatcg ccaaatatta ctgataccat 350

 gaagttcttt ctttatgtgc ttgagtctct tccatctccc acactaactt 400

 gtgcattgac taatggaagc attgaagtcc aatgcatgat accagagcat 450

 tacaacagcc atcgaggact tataatgtac tcatgggatt gtcctatgga 500

 gcaatgtaaa cgtaactcaa ccagtatata ttttaagatg gaaaatgatc 550

 ttccacaaaa aatacagtgt actcttagca atccattatt taatacaaca 600

 tcatcaatca ttttgacaac ctgtatccca agcagcggtc attcaagaca 650

 cagatatgca cttataccca taccattagc agtaattaca acatgtattg 700

 tgctgtatat gaatggtatt ctgaaatgtg acagaaaacc agacagaacc 750

 aactccaatt gattggtaac agaagatgaa gacaacagca taactaaatt 800

 attttaaaaa ctaaaaagcc atctgatttc tcatttgagt attacaattt 850

 ttgaacaact gttggaaatg taacttgaag cagctgcttt aagaagaaat 900

 acccactaac aaagaacaag cattagtttt ggctgtcatc aacttattat 950

 atgactaggt gcttgctttt tttgtcagta aattgttttt actgatgatg 1000

 tagatacttt tgtaaataaa tgtaaatatg tacacaagtg 1040

<210> 3008
<211> 250
<212> PRT
<213> Homo sapien

<400> 3008
 Met Val Ala Gly Ser Asp Ala Gly Arg Ala Leu Gly Val Leu Ser
   1               5                  10                  15

 Val Val Cys Leu Leu His Cys Phe Gly Phe Ile Ser Cys Phe Ser
                  20                  25                  30

 Gln Gln Ile Tyr Gly Val Val Tyr Gly Asn Val Thr Phe His Val
                  35                  40                  45

 Pro Ser Asn Val Pro Leu Lys Glu Val Leu Trp Lys Lys Gln Lys
                  50                  55                  60

 Asp Lys Val Ala Glu Leu Glu Asn Ser Glu Phe Arg Ala Phe Ser
                  65                  70                  75

 Ser Phe Lys Asn Arg Val Tyr Leu Asp Thr Val Ser Gly Ser Leu
                  80                  85                  90

 Thr Ile Tyr Asn Leu Thr Ser Ser Asp Glu Asp Glu Tyr Glu Met
                  95                 100                 105

 Glu Ser Pro Asn Ile Thr Asp Thr Met Lys Phe Phe Leu Tyr Val
                 110                 115                 120

 Leu Glu Ser Leu Pro Ser Pro Thr Leu Thr Cys Ala Leu Thr Asn
                 125                 130                 135

 Gly Ser Ile Glu Val Gln Cys Met Ile Pro Glu His Tyr Asn Ser
                 140                 145                 150

 His Arg Gly Leu Ile Met Tyr Ser Trp Asp Cys Pro Met Glu Gln
                 155                 160                 165

 Cys Lys Arg Asn Ser Thr Ser Ile Tyr Phe Lys Met Glu Asn Asp
                 170                 175                 180

 Leu Pro Gln Lys Ile Gln Cys Thr Leu Ser Asn Pro Leu Phe Asn
                 185                 190                 195

 Thr Thr Ser Ser Ile Ile Leu Thr Thr Cys Ile Pro Ser Ser Gly
                 200                 205                 210

 His Ser Arg His Arg Tyr Ala Leu Ile Pro Ile Pro Leu Ala Val
                 215                 220                 225

 Ile Thr Thr Cys Ile Val Leu Tyr Met Asn Gly Ile Leu Lys Cys
                 230                 235                 240

 Asp Arg Lys Pro Asp Arg Thr Asn Ser Asn
                 245                 250

<210> 3009
<211> 8789
<212> DNA
<213> Homo sapien

<400> 3009
 atgtctgaca aaatgtcgag tttcctacat attggagaca tttgttctct 50

 gtacgcggag ggatcgacaa atggatttat tagcaccttg ggcctggttg 100

 atgatcgttg tgttgtacag ccagaaaccg gggaccttaa caatccacct 150

 aagaaattca gagactgcct ctttaagcta tgtcccatga accgctactc 200

 tgcccaaaag cagttctgga aagccgctaa gcctggggcc aacagcacca 250

 cagacgcagt gctactcaac aaactgcacc acgctgcaga cttggaaaag 300

 aagcagaatg agacagaaaa caggaaattg ctggggaccg taatccagta 350

 tggcaatgtg atccagctcc tgcatttgaa aagtaataaa tacctaacag 400

 tgaataagag gcttcctgct ctgttggaga agaatgccat gagagtcaca 450

 ttggacgagg ctggaaatga agggtcctgg ttttatattc agccattcta 500

 caagctgcga tccattggag acagcgtggt cataggtgac aaggtggttc 550

 tgaaccccgt caatgctggt cagcccctac atgctagcag ccatcaactg 600

 gtagataacc caggctgcaa tgaggtcaat tccgtcaact gcaatacaag 650

 ctggaaaata gtccttttca tgaaatggag tgataacaaa gacgacatat 700

 taaagggggg tgacgtggtg aggctgtttc atgctgagca ggagaagttt 750

 ctcacctgtg acgaacacag gaagaagcag cacgtcttcc tgagaaccac 800

 gggccggcag tcggccacat ctgccaccag ttcaaaagcc ctgtgggagg 850

 tggaggtggt ccagcatgac ccatgtcggg gcggagcagg gtattggaac 900

 agccttttcc gtttcaagca tctggccacg gggcattact tggcagcaga 950

 ggtggaccct gatcaggacg cctctcgaag taggttgcgg aatgcccaag 1000

 aaaagatggt atactccctg gtctctgtgc ctgaaggcaa tgacatctcc 1050

 tccattttcg agctagatcc caccactctg cgtggaggtg acagccttgt 1100

 cccaaggaac tcttatgttc ggctcagaca cctatgtact aatacctggg 1150

 ttcacagcac aaatattcct attgacaagg aagaagaaaa gcccgtgatg 1200

 ctgaaaattg gcacctctcc tgtgaaggag gataaggaag catttgccat 1250

 agttccggtt tctcctgctg aagttcggga cctggacttc gccaatgatg 1300

 ccagcaaggt gctgggctcc attgctggga agctagagaa gggcaccatc 1350

 acccagaatg aaaggaggtc tgtaaccaag ctgctagaag atttggttta 1400

 cttcgtcact ggtggaacta attctggtca agatgttctc gaagttgtct 1450

 tctccaagcc caacagagaa cggcagaaac tgatgagaga acagaatatt 1500

 ctcaagcaga tcttcaagtt gttacaagcc ccattcacag actgcggtga 1550

 tggcccaatg cttcggctgg aagagctcgg ggaccagcgg cacgctcctt 1600

 tcagacacat ctgccggctc tgctacaggg tgctgagaca ctcgcagcaa 1650

 gactacagga agaaccagga gtatatagcc aagcagtttg gcttcatgca 1700

 gaagcagatt ggctatgatg tgttggctga agacactatc actgccctgc 1750

 tccacaataa tcggaaactc ctggaaaaac acattaccgc ggcagagatt 1800

 gacacatttg tcagcctggt gcgaaagaac agggagccca gattcttaga 1850

 ttacctctcc gacctctgtg tctccatgaa caaatcaatt ccagtgaccc 1900

 aggaactgat atgtaaagct gtgctgaacc ccaccaacgc tgacatcctg 1950

 attgagacca aattggttct ttctcgtttt gaatttgaag gtgtctcttc 2000

 cactggagag aatgctctgg aggcaggaga agacgaggaa gaggtgtggc 2050

 tgttttggag ggacagcaac aaagagattc gcagcaagag tgtgagggaa 2100

 ttggctcagg atgctaaaga agggcagaag gaggaccgag acgttctcag 2150

 ctactacaga tatcagctga acctctttgc gaggatgtgt ctggaccgcc 2200

 aatacctggc catcaacgaa atctcaggcc agctggatgt cgatctcatt 2250

 ctccgctgca tgtctgacga gaacctgccc tatgacctca gggcgtcctt 2300

 ctgccgcctc atgcttcaca tgcatgtgga ccgagatccc caggaacaag 2350

 tcacccccgt gaaatatgcc cgcctctggt cggagattcc ctcggagatc 2400

 gccattgacg actatgatag tagtggagct tccaaagatg aaattaagga 2450

 gagatttgct cagaccatgg agtttgtgga ggagtattta agagatgtgg 2500

 tttgtcagag gttccctttc tctgataaag agaagaataa gcttacgttt 2550

 gaggttgtaa atttagctag gaatctcata tactttggtt tctacaactt 2600

 ctctgacctt ctacgattaa ctaagatcct tctggccata ttggactgtg 2650

 tacatgtgac aacaatcttc cccattagca agatggcgaa aggagaagag 2700

 aataaaggta acaatgatgt ggagaagctg aagagcagta acgtgatgag 2750

 atctattcat ggcgtgggag agctgatgac ccaggtggtg ctccggggag 2800

 gaggcttttt gcccatgact cccatggctg ctgcccctga aggcaatgtg 2850

 aagcaggcag agcctgagaa ggaggacatc atggtcatgg acaccaagct 2900

 gaagatcatt gagatactcc agtttatttt gaatgtgagg ttggattata 2950

 ggatctcctg cctcctgtgt atatttaagc gagagtttga tgaaagcaat 3000

 tcccagactt cagaaacatc ctccggaaac agcagccaag aagggccaag 3050

 taatgtacca ggtgctcttg actttgaaca cattgaagaa caagcagaag 3100

 gcatctttgg aggaagtgag gagaacaccc cactggactt ggatgaccac 3150

 ggcggcagaa cctttctccg tgtcctgctc cacttgacga tgcatgacta 3200

 cccacccctg gtgtcagggg ccctgcagct cctcttccgg cacttcagcc 3250

 agaggcagga ggtgctccag gccttcaaac aggttcaact gctggttacc 3300

 agccaagatg tggacaacta caaacagatc aaacaagact tggatcaact 3350

 gaggtccatc gtggaaaagt cagagctttg ggtgtacaaa gggcagggcc 3400

 ccgatgagac tatggatggt gcatctggag aaaatgaaca taagaaaacg 3450

 gaggagggaa ataacaagcc acaaaagcat gaaagcacca gcagctacaa 3500

 ctacagagtg gtcaaagaga ttttgattcg gcttagcaaa ctctgtgttc 3550

 aagagagtgc ctcagtgaga aagagcagga agcagcaaca gcgtctgctc 3600

 cggaacatgg gcgcgcacgc cgtggtgctg gagctgctgc agattcccta 3650

 tgagaaggcc gaagatacca agatgcaaga gataatgagg ttggctcatg 3700

 aatttttgca gaatttctgc gcaggcaacc agcagaatca agctttgcta 3750

 cataaacaca taaacctgtt tctcaaccca gggatcctgg aggcagtaac 3800

 catgcagcac atcttcatga acaatttcca gctttgcagt gagatcaacg 3850

 agagagttgt tcagcacttc gttcactgca tagagactca cggtcggaat 3900

 gtccagtata taaagttctt acagacaatt gtcaaggcag aagggaaatt 3950

 tattaaaaaa tgccaagaca tggttatggc cgagctggtc aattcgggag 4000

 aggatgtcct cgtgttctac aacgacagag cctctttcca gactctgatc 4050

 cagatgatgc ggtcagaacg ggatcggatg gatgagaaca gccctctcat 4100

 gtaccacatc cacttggtcg agctcctggc tgtgtgcacg gagggtaaga 4150

 atgtctacac agagatcaag tgcaactccc tgctcccgct ggatgacatc 4200

 gttcgcgtgg tgacccacga ggactgcatc cctgaggtta aaattgcata 4250

 cattaacttc ctgaatcact gctatgtgga tacagaggtg gaaatgaagg 4300

 agatttatac cagcaatcac atgtggaaat tgtttgagaa tttccttgta 4350

 gacatctgca gggcctgtaa caacactagt gacaggaaac atgcagactc 4400

 gattttggag aagtatgtca ccgaaatcgt catgagtatt gttactactt 4450

 tcttcagctc tcccttctca gaccagagta cgactttgca gactcgccag 4500

 cctgtctttg tgcaactgct gcaaggcgtg ttcagggttt accactgcaa 4550

 ctggttaatg ccaagccaaa aagcctccgt ggagagctgt attcgggtgc 4600

 tgtctgatgt agccaagagc cgggccattg ccattcccgt ggacctggac 4650

 agccaagtca acaacctctt tctcaagtcc cacagcattg tgcagaaaac 4700

 agccatgaac tggcggctct cagcccgcaa tgccgcacgc agggactctg 4750

 ttctggcagc ttccagagac taccggaata tcattgagag attgcaggac 4800

 atcgtctccg cgctggagga ccgtctcagg cccctggtgc aggcagagtt 4850

 atctgtgctc gtggatgttc tccacagacc cgagctgctt ttcccagaga 4900

 acacagacgc cagaaggaaa tgtgaaagtg gcggtttcat ttgcaagtta 4950

 ataaagcata caaaacagct gctagaagaa aatgaagaga agctctgcat 5000

 taaggtccta cagaccctga gggaaatgat gaccaaagat agaggctatg 5050

 gagaaaagct aatttccatt gatgaattgg ataatgctga gcttcctcca 5100

 gctccggatt ctgagaacgc cactgaggag cttgaaccaa gtccacccct 5150

 gcggcagctg gaagaccata aaaggggtga ggcgctcagg caagttctgg 5200

 tcaaccgtta ctatggaaac gtcagacctt cgggacgaag agagagcctt 5250

 accagctttg gcaatggccc actgtcagca ggaggacccg gcaagcccgg 5300

 gggaggaggg ggaggttccg gatccagctc tatgagcagg ggtgagatga 5350

 gtctggccga ggttcagtgt caccttgaca aggagggggc ttccaatcta 5400

 gttatcgacc tcatcatgaa cgcatccagt gaccgagtgt tccatgaaag 5450

 cattctcctg gccattgccc ttctggaagg aggcaacacc accatccagc 5500

 actccttttt ctgtcgcttg acagaagata agaagtcaga gaaattcttt 5550

 aaggtgtttt atgaccggat gaaggtggcc cagcaagaaa tcaaagcaac 5600

 agtgacagtg aacaccagtg acttgggaaa taaaaagaaa gacgatgagg 5650

 tagacaggga tgccccatca cggaaaaaag ctaaagagcc cacaacacag 5700

 ataacagaag aggtccggga tcagctcctg gaggcctccg ctgccaccag 5750

 gaaagccttc accactttca ggagggaggc tgatcccgac gaccactacc 5800

 agcctggaga gggcacccag gccactgccg acaaggccaa ggacgacctg 5850

 gagatgagcg cggtcatcac catcatgcag cccatcctcc gcttccttca 5900

 gctcctgtgt gaaaaccaca accgagacct gcagaacttc ctccgttgcc 5950

 aaaataacaa gaccaactac aatttggtat gtgagaccct gcagtttctg 6000

 gactgtattt gtggaagcac aactggaggc cttggtcttc tgggcttgta 6050

 tataaatgaa aagaacgtag cgcttatcaa ccaaaccctg gaaagtctga 6100

 ccgaatactg tcaaggacct tgccatgaga accagaactg catagccacc 6150

 catgaatcca atggcattga catcatcaca gccctgatcc tcaatgatat 6200

 caatcctttg ggaaagaaga ggatggacct tgtgttagaa ctgaagaaca 6250

 atgcctcgaa gttgctcctg gccatcatgg aaagcaggca cgacagtgaa 6300

 aacgcagaga ggatacttta taacatgagg cccaaggaac tggtggaagt 6350

 gatcaagaaa gcctacatgc aaggtgaagt ggaatttgag gatggagaaa 6400

 acggtgagga tggggcggcg tcccccagga acgtggggca caacatctac 6450

 atattagccc atcagttggc tcggcataac aaagaacttc agagcatgct 6500

 gaaacctggt ggccaagtgg acggagatga agccctggag ttttatgcca 6550

 agcacacggc gcagatagag attgtcagat tagaccgaac aatggaacag 6600

 atagtctttc ccgtgcccag catatgtgaa ttcctaacca aggagtcaaa 6650

 actacgaatt tactatacta cggagagaga cgaacaaggc agcaaaatca 6700

 atgatttctt tctgcggtct gaagacctct tcaatgaaat gaattggcag 6750

 aagaaactga gagcccagcc cgtgttgtac tggtgtgccc gcaacatgtc 6800

 tttctggagc agcatttcgt ttaacctggc cgtcctgatg aacctgctgg 6850

 tggcgttttt ctacccgttt aagggagtcc gaggaggaac cctggagccc 6900

 cactggtcgg gactcctgtg gacagccatg ctcatctctc tggccatcgt 6950

 cattgccctc cccaagcccc atggcatccg ggccttaatt gcctccacaa 7000

 ttctacgatt gatattttca gtcgggttac aacccacgtt gtttcttctg 7050

 ggcgctttca atgtatgcaa taaaatcatc tttctaatga gctttgtggg 7100

 caactgtggg acattcacaa gaggctaccg agccatggtt ctggatgttg 7150

 agttcctcta tcacttgttg tatctggtga tctgtgccat ggggctcttt 7200

 gtccatgaat tcttctacag tctgctgctt tttgatttag tgtacagaga 7250

 agagactttg cttaatgtca ttaaaagtgt cactcgcaat ggacgggcca 7300

 tcatcctgac agcagttctg gctctgatcc tcgtttacct gttctcaata 7350

 gtgggctatc ttttcttcaa ggatgacttt atcttggaag tagataggct 7400

 gcccaatgaa acagctgttc cagaaaccgg cgagagtttg gcaagcgagt 7450

 tcctgttctc cgatgtgtgt agggtggaga gtggggagaa ctgctcctct 7500

 cctgcaccca gagaagagct ggtccctgca gaagagacgg aacaggataa 7550

 agagcacaca tgtgagacgc tgctgatgtg cattgtcact gtgctgagtc 7600

 acgggctgcg gagcgggggt ggagtaggag atgtactcag gaagccgtcc 7650

 aaagaggaac ccctgtttgc tgctagagtt atttatgacc tcttgttctt 7700

 cttcatggtc atcatcattg ttcttaacct gatttttggg gttatcattg 7750

 acacttttgc tgacctgagg agtgagaagc agaagaagga agagatcttg 7800

 aagaccacgt gctttatctg tggcttggaa agagacaagt ttgacaacaa 7850

 gactgtcacc tttgaagagc acatcaagga agaacacaac atgtggcact 7900

 atctgtgctt catcgtcctg gtgaaagtaa aggactccac cgaatatact 7950

 gggcctgaga gttacgtggc agaaatgatc aaggaaagaa accttgactg 8000

 gttccccagg atgagagcca tgtcattggt cagcagtgat tctgaaggag 8050

 aacagaatga gctgagaaac ctgcaggaga agctggagtc caccatgaaa 8100

 cttgtcacga acctttctgg ccagctgtcg gaattaaagg atcagatgac 8150

 agaacaaagg aagcagaaac aaagaattgg tcttctagga catcctcctc 8200

 acatgaatgt caacccacaa caaccagcat aagcaaatga aagaaaggaa 8250

 ttgtatttac cttttataat tattattagt gtgggaatgg ctaatgagtt 8300

 ctgattcacc cacgaaggtt acatttatgc tgaatacatt tgtaaatact 8350

 cagttttata ctgtatgtat atgattgcta ctctaaaggt ttggatatat 8400

 gtattgtaat tagaattgtt ggcatgatga catttcattt gtgccaaaaa 8450

 tattaaaaat gccttttttg gaaggactaa cagaaagcac ctgatttgca 8500

 cttgaaccag attatagatt taaaagtata tgacatgtat tttgtattta 8550

 aaactagaat agccagtatt tatgtttttt ataaaactgt gcaatacgaa 8600

 ttatgcaatc acaatacatt tgtagctccc gagtgtccta aagggagtgc 8650

 acttctttga agctggtgtg ttaatactat gtaataaatg gttaactttc 8700

 aaatgatgct gctgccaaaa ttatattaat agagagtttc aggcccctgg 8750

 gaattcctgc agcccggggg atccccgggt accgagctc 8789

<210> 3010
<211> 2743
<212> PRT
<213> Homo sapien

<400> 3010
 Met Ser Asp Lys Met Ser Ser Phe Leu His Ile Gly Asp Ile Cys
   1               5                  10                  15

 Ser Leu Tyr Ala Glu Gly Ser Thr Asn Gly Phe Ile Ser Thr Leu
                  20                  25                  30

 Gly Leu Val Asp Asp Arg Cys Val Val Gln Pro Glu Thr Gly Asp
                  35                  40                  45

 Leu Asn Asn Pro Pro Lys Lys Phe Arg Asp Cys Leu Phe Lys Leu
                  50                  55                  60

 Cys Pro Met Asn Arg Tyr Ser Ala Gln Lys Gln Phe Trp Lys Ala
                  65                  70                  75

 Ala Lys Pro Gly Ala Asn Ser Thr Thr Asp Ala Val Leu Leu Asn
                  80                  85                  90

 Lys Leu His His Ala Ala Asp Leu Glu Lys Lys Gln Asn Glu Thr
                  95                 100                 105

 Glu Asn Arg Lys Leu Leu Gly Thr Val Ile Gln Tyr Gly Asn Val
                 110                 115                 120

 Ile Gln Leu Leu His Leu Lys Ser Asn Lys Tyr Leu Thr Val Asn
                 125                 130                 135

 Lys Arg Leu Pro Ala Leu Leu Glu Lys Asn Ala Met Arg Val Thr
                 140                 145                 150

 Leu Asp Glu Ala Gly Asn Glu Gly Ser Trp Phe Tyr Ile Gln Pro
                 155                 160                 165

 Phe Tyr Lys Leu Arg Ser Ile Gly Asp Ser Val Val Ile Gly Asp
                 170                 175                 180

 Lys Val Val Leu Asn Pro Val Asn Ala Gly Gln Pro Leu His Ala
                 185                 190                 195

 Ser Ser His Gln Leu Val Asp Asn Pro Gly Cys Asn Glu Val Asn
                 200                 205                 210

 Ser Val Asn Cys Asn Thr Ser Trp Lys Ile Val Leu Phe Met Lys
                 215                 220                 225

 Trp Ser Asp Asn Lys Asp Asp Ile Leu Lys Gly Gly Asp Val Val
                 230                 235                 240

 Arg Leu Phe His Ala Glu Gln Glu Lys Phe Leu Thr Cys Asp Glu
                 245                 250                 255

 His Arg Lys Lys Gln His Val Phe Leu Arg Thr Thr Gly Arg Gln
                 260                 265                 270

 Ser Ala Thr Ser Ala Thr Ser Ser Lys Ala Leu Trp Glu Val Glu
                 275                 280                 285

 Val Val Gln His Asp Pro Cys Arg Gly Gly Ala Gly Tyr Trp Asn
                 290                 295                 300

 Ser Leu Phe Arg Phe Lys His Leu Ala Thr Gly His Tyr Leu Ala
                 305                 310                 315

 Ala Glu Val Asp Pro Asp Gln Asp Ala Ser Arg Ser Arg Leu Arg
                 320                 325                 330

 Asn Ala Gln Glu Lys Met Val Tyr Ser Leu Val Ser Val Pro Glu
                 335                 340                 345

 Gly Asn Asp Ile Ser Ser Ile Phe Glu Leu Asp Pro Thr Thr Leu
                 350                 355                 360

 Arg Gly Gly Asp Ser Leu Val Pro Arg Asn Ser Tyr Val Arg Leu
                 365                 370                 375

 Arg His Leu Cys Thr Asn Thr Trp Val His Ser Thr Asn Ile Pro
                 380                 385                 390

 Ile Asp Lys Glu Glu Glu Lys Pro Val Met Leu Lys Ile Gly Thr
                 395                 400                 405

 Ser Pro Val Lys Glu Asp Lys Glu Ala Phe Ala Ile Val Pro Val
                 410                 415                 420

 Ser Pro Ala Glu Val Arg Asp Leu Asp Phe Ala Asn Asp Ala Ser
                 425                 430                 435

 Lys Val Leu Gly Ser Ile Ala Gly Lys Leu Glu Lys Gly Thr Ile
                 440                 445                 450

 Thr Gln Asn Glu Arg Arg Ser Val Thr Lys Leu Leu Glu Asp Leu
                 455                 460                 465

 Val Tyr Phe Val Thr Gly Gly Thr Asn Ser Gly Gln Asp Val Leu
                 470                 475                 480

 Glu Val Val Phe Ser Lys Pro Asn Arg Glu Arg Gln Lys Leu Met
                 485                 490                 495

 Arg Glu Gln Asn Ile Leu Lys Gln Ile Phe Lys Leu Leu Gln Ala
                 500                 505                 510

 Pro Phe Thr Asp Cys Gly Asp Gly Pro Met Leu Arg Leu Glu Glu
                 515                 520                 525

 Leu Gly Asp Gln Arg His Ala Pro Phe Arg His Ile Cys Arg Leu
                 530                 535                 540

 Cys Tyr Arg Val Leu Arg His Ser Gln Gln Asp Tyr Arg Lys Asn
                 545                 550                 555

 Gln Glu Tyr Ile Ala Lys Gln Phe Gly Phe Met Gln Lys Gln Ile
                 560                 565                 570

 Gly Tyr Asp Val Leu Ala Glu Asp Thr Ile Thr Ala Leu Leu His
                 575                 580                 585

 Asn Asn Arg Lys Leu Leu Glu Lys His Ile Thr Ala Ala Glu Ile
                 590                 595                 600

 Asp Thr Phe Val Ser Leu Val Arg Lys Asn Arg Glu Pro Arg Phe
                 605                 610                 615

 Leu Asp Tyr Leu Ser Asp Leu Cys Val Ser Met Asn Lys Ser Ile
                 620                 625                 630

 Pro Val Thr Gln Glu Leu Ile Cys Lys Ala Val Leu Asn Pro Thr
                 635                 640                 645

 Asn Ala Asp Ile Leu Ile Glu Thr Lys Leu Val Leu Ser Arg Phe
                 650                 655                 660

 Glu Phe Glu Gly Val Ser Ser Thr Gly Glu Asn Ala Leu Glu Ala
                 665                 670                 675

 Gly Glu Asp Glu Glu Glu Val Trp Leu Phe Trp Arg Asp Ser Asn
                 680                 685                 690

 Lys Glu Ile Arg Ser Lys Ser Val Arg Glu Leu Ala Gln Asp Ala
                 695                 700                 705

 Lys Glu Gly Gln Lys Glu Asp Arg Asp Val Leu Ser Tyr Tyr Arg
                 710                 715                 720

 Tyr Gln Leu Asn Leu Phe Ala Arg Met Cys Leu Asp Arg Gln Tyr
                 725                 730                 735

 Leu Ala Ile Asn Glu Ile Ser Gly Gln Leu Asp Val Asp Leu Ile
                 740                 745                 750

 Leu Arg Cys Met Ser Asp Glu Asn Leu Pro Tyr Asp Leu Arg Ala
                 755                 760                 765

 Ser Phe Cys Arg Leu Met Leu His Met His Val Asp Arg Asp Pro
                 770                 775                 780

 Gln Glu Gln Val Thr Pro Val Lys Tyr Ala Arg Leu Trp Ser Glu
                 785                 790                 795

 Ile Pro Ser Glu Ile Ala Ile Asp Asp Tyr Asp Ser Ser Gly Ala
                 800                 805                 810

 Ser Lys Asp Glu Ile Lys Glu Arg Phe Ala Gln Thr Met Glu Phe
                 815                 820                 825

 Val Glu Glu Tyr Leu Arg Asp Val Val Cys Gln Arg Phe Pro Phe
                 830                 835                 840

 Ser Asp Lys Glu Lys Asn Lys Leu Thr Phe Glu Val Val Asn Leu
                 845                 850                 855

 Ala Arg Asn Leu Ile Tyr Phe Gly Phe Tyr Asn Phe Ser Asp Leu
                 860                 865                 870

 Leu Arg Leu Thr Lys Ile Leu Leu Ala Ile Leu Asp Cys Val His
                 875                 880                 885

 Val Thr Thr Ile Phe Pro Ile Ser Lys Met Ala Lys Gly Glu Glu
                 890                 895                 900

 Asn Lys Gly Asn Asn Asp Val Glu Lys Leu Lys Ser Ser Asn Val
                 905                 910                 915

 Met Arg Ser Ile His Gly Val Gly Glu Leu Met Thr Gln Val Val
                 920                 925                 930

 Leu Arg Gly Gly Gly Phe Leu Pro Met Thr Pro Met Ala Ala Ala
                 935                 940                 945

 Pro Glu Gly Asn Val Lys Gln Ala Glu Pro Glu Lys Glu Asp Ile
                 950                 955                 960

 Met Val Met Asp Thr Lys Leu Lys Ile Ile Glu Ile Leu Gln Phe
                 965                 970                 975

 Ile Leu Asn Val Arg Leu Asp Tyr Arg Ile Ser Cys Leu Leu Cys
                 980                 985                 990

 Ile Phe Lys Arg Glu Phe Asp Glu Ser Asn Ser Gln Thr Ser Glu
                 995                1000                1005

 Thr Ser Ser Gly Asn Ser Ser Gln Glu Gly Pro Ser Asn Val Pro
                1010                1015                1020

 Gly Ala Leu Asp Phe Glu His Ile Glu Glu Gln Ala Glu Gly Ile
                1025                1030                1035

 Phe Gly Gly Ser Glu Glu Asn Thr Pro Leu Asp Leu Asp Asp His
                1040                1045                1050

 Gly Gly Arg Thr Phe Leu Arg Val Leu Leu His Leu Thr Met His
                1055                1060                1065

 Asp Tyr Pro Pro Leu Val Ser Gly Ala Leu Gln Leu Leu Phe Arg
                1070                1075                1080

 His Phe Ser Gln Arg Gln Glu Val Leu Gln Ala Phe Lys Gln Val
                1085                1090                1095

 Gln Leu Leu Val Thr Ser Gln Asp Val Asp Asn Tyr Lys Gln Ile
                1100                1105                1110

 Lys Gln Asp Leu Asp Gln Leu Arg Ser Ile Val Glu Lys Ser Glu
                1115                1120                1125

 Leu Trp Val Tyr Lys Gly Gln Gly Pro Asp Glu Thr Met Asp Gly
                1130                1135                1140

 Ala Ser Gly Glu Asn Glu His Lys Lys Thr Glu Glu Gly Asn Asn
                1145                1150                1155

 Lys Pro Gln Lys His Glu Ser Thr Ser Ser Tyr Asn Tyr Arg Val
                1160                1165                1170

 Val Lys Glu Ile Leu Ile Arg Leu Ser Lys Leu Cys Val Gln Glu
                1175                1180                1185

 Ser Ala Ser Val Arg Lys Ser Arg Lys Gln Gln Gln Arg Leu Leu
                1190                1195                1200

 Arg Asn Met Gly Ala His Ala Val Val Leu Glu Leu Leu Gln Ile
                1205                1210                1215

 Pro Tyr Glu Lys Ala Glu Asp Thr Lys Met Gln Glu Ile Met Arg
                1220                1225                1230

 Leu Ala His Glu Phe Leu Gln Asn Phe Cys Ala Gly Asn Gln Gln
                1235                1240                1245

 Asn Gln Ala Leu Leu His Lys His Ile Asn Leu Phe Leu Asn Pro
                1250                1255                1260

 Gly Ile Leu Glu Ala Val Thr Met Gln His Ile Phe Met Asn Asn
                1265                1270                1275

 Phe Gln Leu Cys Ser Glu Ile Asn Glu Arg Val Val Gln His Phe
                1280                1285                1290

 Val His Cys Ile Glu Thr His Gly Arg Asn Val Gln Tyr Ile Lys
                1295                1300                1305

 Phe Leu Gln Thr Ile Val Lys Ala Glu Gly Lys Phe Ile Lys Lys
                1310                1315                1320

 Cys Gln Asp Met Val Met Ala Glu Leu Val Asn Ser Gly Glu Asp
                1325                1330                1335

 Val Leu Val Phe Tyr Asn Asp Arg Ala Ser Phe Gln Thr Leu Ile
                1340                1345                1350

 Gln Met Met Arg Ser Glu Arg Asp Arg Met Asp Glu Asn Ser Pro
                1355                1360                1365

 Leu Met Tyr His Ile His Leu Val Glu Leu Leu Ala Val Cys Thr
                1370                1375                1380

 Glu Gly Lys Asn Val Tyr Thr Glu Ile Lys Cys Asn Ser Leu Leu
                1385                1390                1395

 Pro Leu Asp Asp Ile Val Arg Val Val Thr His Glu Asp Cys Ile
                1400                1405                1410

 Pro Glu Val Lys Ile Ala Tyr Ile Asn Phe Leu Asn His Cys Tyr
                1415                1420                1425

 Val Asp Thr Glu Val Glu Met Lys Glu Ile Tyr Thr Ser Asn His
                1430                1435                1440

 Met Trp Lys Leu Phe Glu Asn Phe Leu Val Asp Ile Cys Arg Ala
                1445                1450                1455

 Cys Asn Asn Thr Ser Asp Arg Lys His Ala Asp Ser Ile Leu Glu
                1460                1465                1470

 Lys Tyr Val Thr Glu Ile Val Met Ser Ile Val Thr Thr Phe Phe
                1475                1480                1485

 Ser Ser Pro Phe Ser Asp Gln Ser Thr Thr Leu Gln Thr Arg Gln
                1490                1495                1500

 Pro Val Phe Val Gln Leu Leu Gln Gly Val Phe Arg Val Tyr His
                1505                1510                1515

 Cys Asn Trp Leu Met Pro Ser Gln Lys Ala Ser Val Glu Ser Cys
                1520                1525                1530

 Ile Arg Val Leu Ser Asp Val Ala Lys Ser Arg Ala Ile Ala Ile
                1535                1540                1545

 Pro Val Asp Leu Asp Ser Gln Val Asn Asn Leu Phe Leu Lys Ser
                1550                1555                1560

 His Ser Ile Val Gln Lys Thr Ala Met Asn Trp Arg Leu Ser Ala
                1565                1570                1575

 Arg Asn Ala Ala Arg Arg Asp Ser Val Leu Ala Ala Ser Arg Asp
                1580                1585                1590

 Tyr Arg Asn Ile Ile Glu Arg Leu Gln Asp Ile Val Ser Ala Leu
                1595                1600                1605

 Glu Asp Arg Leu Arg Pro Leu Val Gln Ala Glu Leu Ser Val Leu
                1610                1615                1620

 Val Asp Val Leu His Arg Pro Glu Leu Leu Phe Pro Glu Asn Thr
                1625                1630                1635

 Asp Ala Arg Arg Lys Cys Glu Ser Gly Gly Phe Ile Cys Lys Leu
                1640                1645                1650

 Ile Lys His Thr Lys Gln Leu Leu Glu Glu Asn Glu Glu Lys Leu
                1655                1660                1665

 Cys Ile Lys Val Leu Gln Thr Leu Arg Glu Met Met Thr Lys Asp
                1670                1675                1680

 Arg Gly Tyr Gly Glu Lys Leu Ile Ser Ile Asp Glu Leu Asp Asn
                1685                1690                1695

 Ala Glu Leu Pro Pro Ala Pro Asp Ser Glu Asn Ala Thr Glu Glu
                1700                1705                1710

 Leu Glu Pro Ser Pro Pro Leu Arg Gln Leu Glu Asp His Lys Arg
                1715                1720                1725

 Gly Glu Ala Leu Arg Gln Val Leu Val Asn Arg Tyr Tyr Gly Asn
                1730                1735                1740

 Val Arg Pro Ser Gly Arg Arg Glu Ser Leu Thr Ser Phe Gly Asn
                1745                1750                1755

 Gly Pro Leu Ser Ala Gly Gly Pro Gly Lys Pro Gly Gly Gly Gly
                1760                1765                1770

 Gly Gly Ser Gly Ser Ser Ser Met Ser Arg Gly Glu Met Ser Leu
                1775                1780                1785

 Ala Glu Val Gln Cys His Leu Asp Lys Glu Gly Ala Ser Asn Leu
                1790                1795                1800

 Val Ile Asp Leu Ile Met Asn Ala Ser Ser Asp Arg Val Phe His
                1805                1810                1815

 Glu Ser Ile Leu Leu Ala Ile Ala Leu Leu Glu Gly Gly Asn Thr
                1820                1825                1830

 Thr Ile Gln His Ser Phe Phe Cys Arg Leu Thr Glu Asp Lys Lys
                1835                1840                1845

 Ser Glu Lys Phe Phe Lys Val Phe Tyr Asp Arg Met Lys Val Ala
                1850                1855                1860

 Gln Gln Glu Ile Lys Ala Thr Val Thr Val Asn Thr Ser Asp Leu
                1865                1870                1875

 Gly Asn Lys Lys Lys Asp Asp Glu Val Asp Arg Asp Ala Pro Ser
                1880                1885                1890

 Arg Lys Lys Ala Lys Glu Pro Thr Thr Gln Ile Thr Glu Glu Val
                1895                1900                1905

 Arg Asp Gln Leu Leu Glu Ala Ser Ala Ala Thr Arg Lys Ala Phe
                1910                1915                1920

 Thr Thr Phe Arg Arg Glu Ala Asp Pro Asp Asp His Tyr Gln Pro
                1925                1930                1935

 Gly Glu Gly Thr Gln Ala Thr Ala Asp Lys Ala Lys Asp Asp Leu
                1940                1945                1950

 Glu Met Ser Ala Val Ile Thr Ile Met Gln Pro Ile Leu Arg Phe
                1955                1960                1965

 Leu Gln Leu Leu Cys Glu Asn His Asn Arg Asp Leu Gln Asn Phe
                1970                1975                1980

 Leu Arg Cys Gln Asn Asn Lys Thr Asn Tyr Asn Leu Val Cys Glu
                1985                1990                1995

 Thr Leu Gln Phe Leu Asp Cys Ile Cys Gly Ser Thr Thr Gly Gly
                2000                2005                2010

 Leu Gly Leu Leu Gly Leu Tyr Ile Asn Glu Lys Asn Val Ala Leu
                2015                2020                2025

 Ile Asn Gln Thr Leu Glu Ser Leu Thr Glu Tyr Cys Gln Gly Pro
                2030                2035                2040

 Cys His Glu Asn Gln Asn Cys Ile Ala Thr His Glu Ser Asn Gly
                2045                2050                2055

 Ile Asp Ile Ile Thr Ala Leu Ile Leu Asn Asp Ile Asn Pro Leu
                2060                2065                2070

 Gly Lys Lys Arg Met Asp Leu Val Leu Glu Leu Lys Asn Asn Ala
                2075                2080                2085

 Ser Lys Leu Leu Leu Ala Ile Met Glu Ser Arg His Asp Ser Glu
                2090                2095                2100

 Asn Ala Glu Arg Ile Leu Tyr Asn Met Arg Pro Lys Glu Leu Val
                2105                2110                2115

 Glu Val Ile Lys Lys Ala Tyr Met Gln Gly Glu Val Glu Phe Glu
                2120                2125                2130

 Asp Gly Glu Asn Gly Glu Asp Gly Ala Ala Ser Pro Arg Asn Val
                2135                2140                2145

 Gly His Asn Ile Tyr Ile Leu Ala His Gln Leu Ala Arg His Asn
                2150                2155                2160

 Lys Glu Leu Gln Ser Met Leu Lys Pro Gly Gly Gln Val Asp Gly
                2165                2170                2175

 Asp Glu Ala Leu Glu Phe Tyr Ala Lys His Thr Ala Gln Ile Glu
                2180                2185                2190

 Ile Val Arg Leu Asp Arg Thr Met Glu Gln Ile Val Phe Pro Val
                2195                2200                2205

 Pro Ser Ile Cys Glu Phe Leu Thr Lys Glu Ser Lys Leu Arg Ile
                2210                2215                2220

 Tyr Tyr Thr Thr Glu Arg Asp Glu Gln Gly Ser Lys Ile Asn Asp
                2225                2230                2235

 Phe Phe Leu Arg Ser Glu Asp Leu Phe Asn Glu Met Asn Trp Gln
                2240                2245                2250

 Lys Lys Leu Arg Ala Gln Pro Val Leu Tyr Trp Cys Ala Arg Asn
                2255                2260                2265

 Met Ser Phe Trp Ser Ser Ile Ser Phe Asn Leu Ala Val Leu Met
                2270                2275                2280

 Asn Leu Leu Val Ala Phe Phe Tyr Pro Phe Lys Gly Val Arg Gly
                2285                2290                2295

 Gly Thr Leu Glu Pro His Trp Ser Gly Leu Leu Trp Thr Ala Met
                2300                2305                2310

 Leu Ile Ser Leu Ala Ile Val Ile Ala Leu Pro Lys Pro His Gly
                2315                2320                2325

 Ile Arg Ala Leu Ile Ala Ser Thr Ile Leu Arg Leu Ile Phe Ser
                2330                2335                2340

 Val Gly Leu Gln Pro Thr Leu Phe Leu Leu Gly Ala Phe Asn Val
                2345                2350                2355

 Cys Asn Lys Ile Ile Phe Leu Met Ser Phe Val Gly Asn Cys Gly
                2360                2365                2370

 Thr Phe Thr Arg Gly Tyr Arg Ala Met Val Leu Asp Val Glu Phe
                2375                2380                2385

 Leu Tyr His Leu Leu Tyr Leu Val Ile Cys Ala Met Gly Leu Phe
                2390                2395                2400

 Val His Glu Phe Phe Tyr Ser Leu Leu Leu Phe Asp Leu Val Tyr
                2405                2410                2415

 Arg Glu Glu Thr Leu Leu Asn Val Ile Lys Ser Val Thr Arg Asn
                2420                2425                2430

 Gly Arg Ala Ile Ile Leu Thr Ala Val Leu Ala Leu Ile Leu Val
                2435                2440                2445

 Tyr Leu Phe Ser Ile Val Gly Tyr Leu Phe Phe Lys Asp Asp Phe
                2450                2455                2460

 Ile Leu Glu Val Asp Arg Leu Pro Asn Glu Thr Ala Val Pro Glu
                2465                2470                2475

 Thr Gly Glu Ser Leu Ala Ser Glu Phe Leu Phe Ser Asp Val Cys
                2480                2485                2490

 Arg Val Glu Ser Gly Glu Asn Cys Ser Ser Pro Ala Pro Arg Glu
                2495                2500                2505

 Glu Leu Val Pro Ala Glu Glu Thr Glu Gln Asp Lys Glu His Thr
                2510                2515                2520

 Cys Glu Thr Leu Leu Met Cys Ile Val Thr Val Leu Ser His Gly
                2525                2530                2535

 Leu Arg Ser Gly Gly Gly Val Gly Asp Val Leu Arg Lys Pro Ser
                2540                2545                2550

 Lys Glu Glu Pro Leu Phe Ala Ala Arg Val Ile Tyr Asp Leu Leu
                2555                2560                2565

 Phe Phe Phe Met Val Ile Ile Ile Val Leu Asn Leu Ile Phe Gly
                2570                2575                2580

 Val Ile Ile Asp Thr Phe Ala Asp Leu Arg Ser Glu Lys Gln Lys
                2585                2590                2595

 Lys Glu Glu Ile Leu Lys Thr Thr Cys Phe Ile Cys Gly Leu Glu
                2600                2605                2610

 Arg Asp Lys Phe Asp Asn Lys Thr Val Thr Phe Glu Glu His Ile
                2615                2620                2625

 Lys Glu Glu His Asn Met Trp His Tyr Leu Cys Phe Ile Val Leu
                2630                2635                2640

 Val Lys Val Lys Asp Ser Thr Glu Tyr Thr Gly Pro Glu Ser Tyr
                2645                2650                2655

 Val Ala Glu Met Ile Lys Glu Arg Asn Leu Asp Trp Phe Pro Arg
                2660                2665                2670

 Met Arg Ala Met Ser Leu Val Ser Ser Asp Ser Glu Gly Glu Gln
                2675                2680                2685

 Asn Glu Leu Arg Asn Leu Gln Glu Lys Leu Glu Ser Thr Met Lys
                2690                2695                2700

 Leu Val Thr Asn Leu Ser Gly Gln Leu Ser Glu Leu Lys Asp Gln
                2705                2710                2715

 Met Thr Glu Gln Arg Lys Gln Lys Gln Arg Ile Gly Leu Leu Gly
                2720                2725                2730

 His Pro Pro His Met Asn Val Asn Pro Gln Gln Pro Ala
                2735                2740

<210> 3011
<211> 1054
<212> DNA
<213> Homo sapien

<400> 3011
 gaattccgcg ggaggccacg ggctttccac agcgcggggg aacgggaggc 50

 tgcaggatgg tcaagctgac ggcggagctg atcgagcagg cggcgcagta 100

 caccaacgcg gtgcgcgacc gggagctgga cctccggggg tataaaattc 150

 ccgtcattga aaatctaggt gctacgttag accagtttga tgctattgat 200

 ttttctgaca atgagatcag gaaactggat ggttttcctt tgttgagaag 250

 actgaaaaca ttgttagtga acaacaacag aatatgccgt ataggtgagg 300

 gacttgatca ggctctgccc tgtctgacag aactcattct caccaataat 350

 agtctcgtgg aactgggtga tctggaccct ctggcatctc tcaaatcgct 400

 gacttaccta agtatcctaa gaaatccggt aaccaataag aagcattaca 450

 gattgtatgt gatttataaa gttccgcaag tcagagtact ggatttccag 500

 aaagtgaaac taaaagagcg tcaggaagca gagaaaatgt tcaagggcaa 550

 acggggtgca cagcttgcaa aggatattgc caggagaagc aaaactttta 600

 atccaggtgc tggtttgcca actgacaaaa agagaggtgg gccatctcca 650

 ggggatgtag aagcaatcaa gaatgccata gcaaatgctt caactctggc 700

 tgaagtggag aggctgaagg ggttgctgca gtctggtcag atccctggca 750

 gagaacgcag atcagggccc actgatgatg gtgaagaaga gatggaagaa 800

 gacacagtca caaacgggtc ctgagcagtg aggcagatgt ataataatag 850

 gccctcttgg aacaagtctt gcttttcgaa catggtataa tagccttgtt 900

 tgtgttagca aagtggaatc tatcagcatt gttgaaatgc ttaagactgc 950

 tgctgataat tttgtaatat aagttttgaa atctaaatgt caattttcta 1000

 caaattataa aaataaactc cactctctat gctaaaaaaa aaaaaaagga 1050

 attc 1054

<210> 3012
<211> 255
<212> PRT
<213> Homo sapien

<400> 3012
 Met Val Lys Leu Thr Ala Glu Leu Ile Glu Gln Ala Ala Gln Tyr
   1               5                  10                  15

 Thr Asn Ala Val Arg Asp Arg Glu Leu Asp Leu Arg Gly Tyr Lys
                  20                  25                  30

 Ile Pro Val Ile Glu Asn Leu Gly Ala Thr Leu Asp Gln Phe Asp
                  35                  40                  45

 Ala Ile Asp Phe Ser Asp Asn Glu Ile Arg Lys Leu Asp Gly Phe
                  50                  55                  60

 Pro Leu Leu Arg Arg Leu Lys Thr Leu Leu Val Asn Asn Asn Arg
                  65                  70                  75

 Ile Cys Arg Ile Gly Glu Gly Leu Asp Gln Ala Leu Pro Cys Leu
                  80                  85                  90

 Thr Glu Leu Ile Leu Thr Asn Asn Ser Leu Val Glu Leu Gly Asp
                  95                 100                 105

 Leu Asp Pro Leu Ala Ser Leu Lys Ser Leu Thr Tyr Leu Ser Ile
                 110                 115                 120

 Leu Arg Asn Pro Val Thr Asn Lys Lys His Tyr Arg Leu Tyr Val
                 125                 130                 135

 Ile Tyr Lys Val Pro Gln Val Arg Val Leu Asp Phe Gln Lys Val
                 140                 145                 150

 Lys Leu Lys Glu Arg Gln Glu Ala Glu Lys Met Phe Lys Gly Lys
                 155                 160                 165

 Arg Gly Ala Gln Leu Ala Lys Asp Ile Ala Arg Arg Ser Lys Thr
                 170                 175                 180

 Phe Asn Pro Gly Ala Gly Leu Pro Thr Asp Lys Lys Arg Gly Gly
                 185                 190                 195

 Pro Ser Pro Gly Asp Val Glu Ala Ile Lys Asn Ala Ile Ala Asn
                 200                 205                 210

 Ala Ser Thr Leu Ala Glu Val Glu Arg Leu Lys Gly Leu Leu Gln
                 215                 220                 225

 Ser Gly Gln Ile Pro Gly Arg Glu Arg Arg Ser Gly Pro Thr Asp
                 230                 235                 240

 Asp Gly Glu Glu Glu Met Glu Glu Asp Thr Val Thr Asn Gly Ser
                 245                 250                 255

<210> 3013
<211> 3383
<212> DNA
<213> Homo sapien

<400> 3013
 ggcggccgga cgcggcccgg aggcgcgggg tcccgatgtg gggcccgggg 50

 ccgcgtggcc tgcgggagcc catcccccac cctacccccc gggcccgggg 100

 gacaggtgtg cacggggcgg ccaagggcac cttcgccacc ttcgagcggg 150

 cgaggtccgg gcggggacgg ggcggggacc gagctagcgg agccagcgca 200

 gcctgcccgg ctcagcccgg cccggccaca gcacaaagga aagcgagggc 250

 gggggaggag cggagcgggc tgggggccag ggcgccccgc ccaccggggg 300

 gcctctcgga gtgggccgcc ctccccccga aacctgggct ggagtgaggt 350

 ggaaggatgt ttgctgccac atggcgaccg cgaagtgact cccttaccgc 400

 cgcgggtcgc ggaggaggca gggggaaggt gcccatctgg ttcctaggcc 450

 tcctctccct gctggcagat gggaacaggt tcttcttgag gaaactgagg 500

 caaagaggag ggcaggtctg agggaccccg cttgggctgg cctcacccgc 550

 acactgggag ggcagccagg tggggactct gacctggggg cttctggagg 600

 agaggatgag atggctgggc atccatggca tggtactgca gcactggcca 650

 gcagccaggc ctggagggat ggacgcgaga gacaagctct cgtgtcctgc 700

 agggctctgt acacatatga agatggctcc gatgacctca agcttgcagc 750

 atcaggagaa gggggcttgc aggagctttc gggacacttt gagaaccaga 800

 aggtgatgta cggcttctgc agtgtcaagg actcccaagc tgctctgcca 850

 aaatacgtgc tcatcaactg ggtgggcgaa gatgtgcctg atgcccgcaa 900

 gtgcgcttgt gccagccacg tggctaaggt ggcagagttc ttccagggtg 950

 tcgacgtgat cgtgaacgcc agcagcgtgg aagacataga cgcgggtgcc 1000

 atcgggcagc ggctctctaa cgggctggcg cgactctcca gccctgtgct 1050

 gcaccgactg cggctgcgag aggatgagaa cgcagagccc gtgggcacca 1100

 cctaccagaa gacggatgca gctgtggaaa tgaagcggat taaccgagag 1150

 cagttctggg agcaggccaa gaaggaagaa gagctgcgga aggaggagga 1200

 gcggaagaag gccctggatg agaggctcag gttcgagcag gagcggatgg 1250

 agcaggagcg gcaggagcaa gaggagcgcg agcggcgcta ccgggagcgg 1300

 gagcagcaga tcgaggagca caggaggaaa cagcagactt tagaagcgga 1350

 agaggccaag aggcggttga aggagcagtc tatctttggt gaccatcggg 1400

 atgaggagga agagacccac atgaagaagt cagagtcgga ggtggaggag 1450

 gcagcagcta ttattgccca gcggcctgac aacccaaggg agttcttcaa 1500

 gcagcaggaa agagtcgcat cggcctctgc gggcagctgt gatgtaccct 1550

 cgcccttcaa ccatcgacca ggcagccacc tggacagcca ccggaggatg 1600

 gcgcccactc ccatccccac gcggagcccg tctgactcca gcaccgcctc 1650

 cacccctgtc gctgagcaga tagagcgggc cctggatgag gtcacctcct 1700

 cgcagcctcc accactgcca ccgccacccc caccagccca agagacccag 1750

 gagcccagcc ccatcctaga cagtgaggag accagagcag cagcccctca 1800

 ggcctgggcc ggccccatgg aggagccccc tcaggcacag gcgcctcccc 1850

 gggggccagg cagccctgca gaggacttga tgttcatgga gtctgcagag 1900

 caggctgtcc tggctgctcc cgtggagcct gccacagctg acgccacgga 1950

 gatccacgat gcagctgaca ccattgaaac tgacactgcc actgctgaca 2000

 ccactgttgc caacaacgta ccccccgccg ccaccagcct cattgaccta 2050

 tggcctggca acggggaagg ggcctccaca ctccagggtg agcccagggc 2100

 ccccacgcca ccctcgggta ctgaggtcac cctggcagag gtgcccctgc 2150

 tggatgaggt ggctccggag ccactgctgc cagcaggcga aggctgtgcc 2200

 acccttctca actttgatga gctgcctgag ccgccagcca ccttctgtga 2250

 cccagaggaa gtggaagggg agcccctggc tgccccccag accccaactc 2300

 tgccctcagc ccttgaggag ctggagcaag agcaggagcc ggagccccac 2350

 ctgctaacca atggcgagac cacccagaag gaggggaccc aggccagtga 2400

 ggggtacttc agtcaatcac aggaggagga gtttgcccaa tcggaagagc 2450

 tctgtgccaa ggctccgcct cctgtgttct acaacaagcc tccagagatc 2500

 gacatcacat gctgggatgc agacccagtt ccagaagagg aggagggctt 2550

 cgagggtggt gattagcggt ggcgccagcc ctaggctacc cttgccaagg 2600

 ccgcccacct gcatcagcct ctggccagac ggcccgccgt gcctgcattc 2650

 gcagcagctc cgcctggcac ccactccgga ttccggccct ggctggggac 2700

 ttggccgctt ccctacccac agggcctgac ttttacagct tttctctttt 2750

 tttaaaaagt tgataggaga cttgtacagt tgactggctt tcctctcgtt 2800

 ggtagttgag acgctgttgc aaattccacc cctccttccc tggtccagat 2850

 tgtagctctt agtcctccct gctcagctgg ccgggttgga ggcctcaccc 2900

 tgcttggggc ctggcgtggg gggagctctg gtgggaaaat gtcccccacc 2950

 tcttttccta gttttatgtt tcttgggaaa atatcacttt gtattctctg 3000

 tccagggctt cagatatttt gcacgaattt taaaacatgg caataaatgg 3050

 ctcgtgggct ctggctccct gggaccccct ccccgccctt cttttgaccc 3100

 cttcctgtct ggcccaaagg aagtagcagg cccagctggg gcccctcggc 3150

 taccccccgt ctcctgccgg gcaggtccca ggttggaggc cctaggcgcg 3200

 gttcaggtca gggctatgga tggggcccag gggctttggt ggcccctccc 3250

 caactccttc ctctttgctt gggttccttt ttcacgttta gtaactgttt 3300

 tttttttttt tttttttttt ttggaaagca caaacttctg taacgggtcg 3350

 tgctcatgtc tgttaataaa gaaatccaga tcc 3383

<210> 3014
<211> 651
<212> PRT
<213> Homo sapien

<400> 3014
 Met Ala Gly His Pro Trp His Gly Thr Ala Ala Leu Ala Ser Ser
   1               5                  10                  15

 Gln Ala Trp Arg Asp Gly Arg Glu Arg Gln Ala Leu Val Ser Cys
                  20                  25                  30

 Arg Ala Leu Tyr Thr Tyr Glu Asp Gly Ser Asp Asp Leu Lys Leu
                  35                  40                  45

 Ala Ala Ser Gly Glu Gly Gly Leu Gln Glu Leu Ser Gly His Phe
                  50                  55                  60

 Glu Asn Gln Lys Val Met Tyr Gly Phe Cys Ser Val Lys Asp Ser
                  65                  70                  75

 Gln Ala Ala Leu Pro Lys Tyr Val Leu Ile Asn Trp Val Gly Glu
                  80                  85                  90

 Asp Val Pro Asp Ala Arg Lys Cys Ala Cys Ala Ser His Val Ala
                  95                 100                 105

 Lys Val Ala Glu Phe Phe Gln Gly Val Asp Val Ile Val Asn Ala
                 110                 115                 120

 Ser Ser Val Glu Asp Ile Asp Ala Gly Ala Ile Gly Gln Arg Leu
                 125                 130                 135

 Ser Asn Gly Leu Ala Arg Leu Ser Ser Pro Val Leu His Arg Leu
                 140                 145                 150

 Arg Leu Arg Glu Asp Glu Asn Ala Glu Pro Val Gly Thr Thr Tyr
                 155                 160                 165

 Gln Lys Thr Asp Ala Ala Val Glu Met Lys Arg Ile Asn Arg Glu
                 170                 175                 180

 Gln Phe Trp Glu Gln Ala Lys Lys Glu Glu Glu Leu Arg Lys Glu
                 185                 190                 195

 Glu Glu Arg Lys Lys Ala Leu Asp Glu Arg Leu Arg Phe Glu Gln
                 200                 205                 210

 Glu Arg Met Glu Gln Glu Arg Gln Glu Gln Glu Glu Arg Glu Arg
                 215                 220                 225

 Arg Tyr Arg Glu Arg Glu Gln Gln Ile Glu Glu His Arg Arg Lys
                 230                 235                 240

 Gln Gln Thr Leu Glu Ala Glu Glu Ala Lys Arg Arg Leu Lys Glu
                 245                 250                 255

 Gln Ser Ile Phe Gly Asp His Arg Asp Glu Glu Glu Glu Thr His
                 260                 265                 270

 Met Lys Lys Ser Glu Ser Glu Val Glu Glu Ala Ala Ala Ile Ile
                 275                 280                 285

 Ala Gln Arg Pro Asp Asn Pro Arg Glu Phe Phe Lys Gln Gln Glu
                 290                 295                 300

 Arg Val Ala Ser Ala Ser Ala Gly Ser Cys Asp Val Pro Ser Pro
                 305                 310                 315

 Phe Asn His Arg Pro Gly Ser His Leu Asp Ser His Arg Arg Met
                 320                 325                 330

 Ala Pro Thr Pro Ile Pro Thr Arg Ser Pro Ser Asp Ser Ser Thr
                 335                 340                 345

 Ala Ser Thr Pro Val Ala Glu Gln Ile Glu Arg Ala Leu Asp Glu
                 350                 355                 360

 Val Thr Ser Ser Gln Pro Pro Pro Leu Pro Pro Pro Pro Pro Pro
                 365                 370                 375

 Ala Gln Glu Thr Gln Glu Pro Ser Pro Ile Leu Asp Ser Glu Glu
                 380                 385                 390

 Thr Arg Ala Ala Ala Pro Gln Ala Trp Ala Gly Pro Met Glu Glu
                 395                 400                 405

 Pro Pro Gln Ala Gln Ala Pro Pro Arg Gly Pro Gly Ser Pro Ala
                 410                 415                 420

 Glu Asp Leu Met Phe Met Glu Ser Ala Glu Gln Ala Val Leu Ala
                 425                 430                 435

 Ala Pro Val Glu Pro Ala Thr Ala Asp Ala Thr Glu Ile His Asp
                 440                 445                 450

 Ala Ala Asp Thr Ile Glu Thr Asp Thr Ala Thr Ala Asp Thr Thr
                 455                 460                 465

 Val Ala Asn Asn Val Pro Pro Ala Ala Thr Ser Leu Ile Asp Leu
                 470                 475                 480

 Trp Pro Gly Asn Gly Glu Gly Ala Ser Thr Leu Gln Gly Glu Pro
                 485                 490                 495

 Arg Ala Pro Thr Pro Pro Ser Gly Thr Glu Val Thr Leu Ala Glu
                 500                 505                 510

 Val Pro Leu Leu Asp Glu Val Ala Pro Glu Pro Leu Leu Pro Ala
                 515                 520                 525

 Gly Glu Gly Cys Ala Thr Leu Leu Asn Phe Asp Glu Leu Pro Glu
                 530                 535                 540

 Pro Pro Ala Thr Phe Cys Asp Pro Glu Glu Val Glu Gly Glu Pro
                 545                 550                 555

 Leu Ala Ala Pro Gln Thr Pro Thr Leu Pro Ser Ala Leu Glu Glu
                 560                 565                 570

 Leu Glu Gln Glu Gln Glu Pro Glu Pro His Leu Leu Thr Asn Gly
                 575                 580                 585

 Glu Thr Thr Gln Lys Glu Gly Thr Gln Ala Ser Glu Gly Tyr Phe
                 590                 595                 600

 Ser Gln Ser Gln Glu Glu Glu Phe Ala Gln Ser Glu Glu Leu Cys
                 605                 610                 615

 Ala Lys Ala Pro Pro Pro Val Phe Tyr Asn Lys Pro Pro Glu Ile
                 620                 625                 630

 Asp Ile Thr Cys Trp Asp Ala Asp Pro Val Pro Glu Glu Glu Glu
                 635                 640                 645

 Gly Phe Glu Gly Gly Asp
                 650

<210> 3015
<211> 1670
<212> DNA
<213> Homo sapien

<400> 3015
 cggcacgagg caagtgacgc cgagggcctg agtgctccag tagccaccgc 50

 atctggagaa ccagcggtta ccatggaggg gatcagtata tacacttcag 100

 ataactacac cgaggaaatg ggctcagggg actatgactc catgaaggaa 150

 ccctgtttcc gtgaagaaaa tgctaatttc aataaaatct tcctgcccac 200

 catctactcc atcatcttct taactggcat tgtgggcaat ggattggtca 250

 tcctggtcat gggttaccag aagaaactga gaagcatgac ggacaagtac 300

 aggctgcacc tgtcagtggc cgacctcctc tttgtcatca cgcttccctt 350

 ctgggcagtt gatgccgtgg caaactggta ctttgggaac ttcctatgca 400

 aggcagtcca tgtcatctac acagtcaacc tctacagcag tgtcctcatc 450

 ctggccttca tcagtctgga ccgctacctg gccatcgtcc acgccaccaa 500

 cagtcagagg ccaaggaagc tgttggctga aaaggtggtc tatgttggcg 550

 tctggatccc tgccctcctg ctgactattc ccgacttcat ctttgccaac 600

 gtcagtgagg cagatgacag atatatctgt gaccgcttct accccaatga 650

 cttgtgggtg gttgtgttcc agtttcagca catcatggtt ggccttatcc 700

 tgcctggtat tgtcatcctg tcctgctatt gcattatcat ctccaagctg 750

 tcacactcca agggccacca gaagcgcaag gccctcaaga ccacagtcat 800

 cctcatcctg gctttcttcg cctgttggct gccttactac attgggatca 850

 gcatcgactc cttcatcctc ctggaaatca tcaagcaagg gtgtgagttt 900

 gagaacactg tgcacaagtg gatttccatc accgaggccc tagctttctt 950

 ccactgttgt ctgaacccca tcctctatgc tttccttgga gccaaattta 1000

 aaacctctgc ccagcacgca ctcacctctg tgagcagagg gtccagcctc 1050

 aagatcctct ccaaaggaaa gcgaggtgga cattcatctg tttccactga 1100

 gtctgagtct tcaagttttc actccagcta acacagatgt aagagacttt 1150

 tttttatacg ataaataact tttttttaag ttacacattt ttcagatata 1200

 aaagactgac caatattgta cagtttttat tgcttgttgg atttttgctc 1250

 ttgtgtttct ttagtttttc gtgaaggttt aattgactta tttatataaa 1300

 ttttttttgt ttcatattga tgtgtgtcta ggcaggacct gtggccaagt 1350

 tcttagttgc tgtatgtctc gtggtaggac tgtagaaaag ggaactgaac 1400

 attccagagc gtgtagtgaa tcacgtaaag ctagaaatga tccccagctg 1450

 tttatgcata gataatctct ccattcccgt ggaacgtttt tcctgttctt 1500

 aagacgtgat tttgctgtag aagatggcac ttataaccaa agcccaaagt 1550

 ggtatagaaa tgctggtttt tcagttttca ggagtgggtt gatttcagca 1600

 cctacagtgt acagtcttgt attaagttgt taataaaagt acatgttaaa 1650

 cttaaaaaaa aaaaaaaaaa 1670

<210> 3016
<211> 352
<212> PRT
<213> Homo sapien

<400> 3016
 Met Glu Gly Ile Ser Ile Tyr Thr Ser Asp Asn Tyr Thr Glu Glu
   1               5                  10                  15

 Met Gly Ser Gly Asp Tyr Asp Ser Met Lys Glu Pro Cys Phe Arg
                  20                  25                  30

 Glu Glu Asn Ala Asn Phe Asn Lys Ile Phe Leu Pro Thr Ile Tyr
                  35                  40                  45

 Ser Ile Ile Phe Leu Thr Gly Ile Val Gly Asn Gly Leu Val Ile
                  50                  55                  60

 Leu Val Met Gly Tyr Gln Lys Lys Leu Arg Ser Met Thr Asp Lys
                  65                  70                  75

 Tyr Arg Leu His Leu Ser Val Ala Asp Leu Leu Phe Val Ile Thr
                  80                  85                  90

 Leu Pro Phe Trp Ala Val Asp Ala Val Ala Asn Trp Tyr Phe Gly
                  95                 100                 105

 Asn Phe Leu Cys Lys Ala Val His Val Ile Tyr Thr Val Asn Leu
                 110                 115                 120

 Tyr Ser Ser Val Leu Ile Leu Ala Phe Ile Ser Leu Asp Arg Tyr
                 125                 130                 135

 Leu Ala Ile Val His Ala Thr Asn Ser Gln Arg Pro Arg Lys Leu
                 140                 145                 150

 Leu Ala Glu Lys Val Val Tyr Val Gly Val Trp Ile Pro Ala Leu
                 155                 160                 165

 Leu Leu Thr Ile Pro Asp Phe Ile Phe Ala Asn Val Ser Glu Ala
                 170                 175                 180

 Asp Asp Arg Tyr Ile Cys Asp Arg Phe Tyr Pro Asn Asp Leu Trp
                 185                 190                 195

 Val Val Val Phe Gln Phe Gln His Ile Met Val Gly Leu Ile Leu
                 200                 205                 210

 Pro Gly Ile Val Ile Leu Ser Cys Tyr Cys Ile Ile Ile Ser Lys
                 215                 220                 225

 Leu Ser His Ser Lys Gly His Gln Lys Arg Lys Ala Leu Lys Thr
                 230                 235                 240

 Thr Val Ile Leu Ile Leu Ala Phe Phe Ala Cys Trp Leu Pro Tyr
                 245                 250                 255

 Tyr Ile Gly Ile Ser Ile Asp Ser Phe Ile Leu Leu Glu Ile Ile
                 260                 265                 270

 Lys Gln Gly Cys Glu Phe Glu Asn Thr Val His Lys Trp Ile Ser
                 275                 280                 285

 Ile Thr Glu Ala Leu Ala Phe Phe His Cys Cys Leu Asn Pro Ile
                 290                 295                 300

 Leu Tyr Ala Phe Leu Gly Ala Lys Phe Lys Thr Ser Ala Gln His
                 305                 310                 315

 Ala Leu Thr Ser Val Ser Arg Gly Ser Ser Leu Lys Ile Leu Ser
                 320                 325                 330

 Lys Gly Lys Arg Gly Gly His Ser Ser Val Ser Thr Glu Ser Glu
                 335                 340                 345

 Ser Ser Ser Phe His Ser Ser
                 350

<210> 3017
<211> 1800
<212> DNA
<213> Homo sapien

<400> 3017
 atgggggagc agccgatctt caccacccga gcgcatgtct tccagattga 50

 ccccaacacc aagaagaact ggatgcctgc gagcaagcag gcggtcaccg 100

 tttcctactt ctatgatgtc acaaggaaca gctatcggat catcagtgtg 150

 gacggagcca aggtgatcat aaacagcaca atcacaccga atatgacctt 200

 caccaaaacg tcacagaagt ttgggcagtg ggccgacagc agagccaaca 250

 cagtgtttgg tttggggttt tcctctgagc agcagctgac aaagtttgca 300

 gagaaattcc aggaggtgaa agaagctgcc aagatagcca aagacaagac 350

 gcaggagaaa atcgagacct caagtaatca ttcccaagaa tctgggcgtg 400

 aaaccccatc ttctactcag gcatccagtg tcaacgggac ggacgaggaa 450

 aaggcctctc acgccggtcc agccaacaca caactgaagt ctgagaatga 500

 caagctgaag attgccttga cgcagagcgc agccaacgtg aagaagtggg 550

 agatcgagct gcagaccctt cgggagagca atgcacggct gaccacagca 600

 ctgcaggagt cggcagccag tgtggagcag tggaagaggc agttctccat 650

 ctgccgtgat gagaatgacc ggctccgcaa caagattgat gagctggaag 700

 aacaatgcag tgagatcaac agagagaagg agaagaacac gcagctgaag 750

 aggaggatcg aggagctgga ggcagagctc cgagaaaagg agacagagct 800

 gaaagatctc cgaaaacaaa gtgaaatcat acctcagctc atgtcagagt 850

 gcgaatatgt ctctgagaag ctagaggcgg cagagagaga caatcaaaac 900

 ctggaagaca aagtgcgttc cttaaagaca gacattgagg agagcaaata 950

 ccgacagcgc cacctgaagg tggagttgaa gagcttcctg gaggtgctgg 1000

 acgggaagat tgacgacctg catgacttcc gccgagggct ctccaagctg 1050

 ggcaccgata actagggctg gccgaggccc aggccccgcc cgtgagtccc 1100

 aagcgtgtgt gcgagaccag atagctctag gacgttcttc tgtgtgcatt 1150

 gcttctgtaa atgcaggcgc agtttgtcgt gtttccaaac cagttgtgcc 1200

 gtccactcac tccttttcag aatagaaatc tcctctcgct tctctggcct 1250

 tgtgaggttg tggacaactg gaagattctg actcaggaat ccagaactag 1300

 gtctaccttc aacatttatg cagtcagggc agggatgttt atatctttca 1350

 taagggctgt tgcaaccata tgaactgaaa aaacacgcat tttgtaatcc 1400

 aaatattgat attctttaca ccaagccatc aggctccttt tatcaaatag 1450

 cattcagagt atttgaatgt ccaccagaca ccagccccgg ggggcacaga 1500

 gagaacaaca ttcctctctg tcaacatcga gaggctttaa aacaactgtt 1550

 tagtggaaac tttctgagag atggaaaaca agcttctggt gggtgcattt 1600

 tctggcccgg agttgcctgc atccacgcta ctgccccctg ccccccgccc 1650

 ccccagtttg tacggttgca acagtgttcc ttttcttggt tttaatttct 1700

 gagcagatga tttgctgtgg gaacagcaca cagtgagggt gcctagcaca 1750

 atgtctggca caaagtaggt gcttaataaa tatttgttca attaaaaaaa 1800

<210> 3018
<211> 354
<212> PRT
<213> Homo sapien

<400> 3018
 Met Gly Glu Gln Pro Ile Phe Thr Thr Arg Ala His Val Phe Gln
   1               5                  10                  15

 Ile Asp Pro Asn Thr Lys Lys Asn Trp Met Pro Ala Ser Lys Gln
                  20                  25                  30

 Ala Val Thr Val Ser Tyr Phe Tyr Asp Val Thr Arg Asn Ser Tyr
                  35                  40                  45

 Arg Ile Ile Ser Val Asp Gly Ala Lys Val Ile Ile Asn Ser Thr
                  50                  55                  60

 Ile Thr Pro Asn Met Thr Phe Thr Lys Thr Ser Gln Lys Phe Gly
                  65                  70                  75

 Gln Trp Ala Asp Ser Arg Ala Asn Thr Val Phe Gly Leu Gly Phe
                  80                  85                  90

 Ser Ser Glu Gln Gln Leu Thr Lys Phe Ala Glu Lys Phe Gln Glu
                  95                 100                 105

 Val Lys Glu Ala Ala Lys Ile Ala Lys Asp Lys Thr Gln Glu Lys
                 110                 115                 120

 Ile Glu Thr Ser Ser Asn His Ser Gln Glu Ser Gly Arg Glu Thr
                 125                 130                 135

 Pro Ser Ser Thr Gln Ala Ser Ser Val Asn Gly Thr Asp Glu Glu
                 140                 145                 150

 Lys Ala Ser His Ala Gly Pro Ala Asn Thr Gln Leu Lys Ser Glu
                 155                 160                 165

 Asn Asp Lys Leu Lys Ile Ala Leu Thr Gln Ser Ala Ala Asn Val
                 170                 175                 180

 Lys Lys Trp Glu Ile Glu Leu Gln Thr Leu Arg Glu Ser Asn Ala
                 185                 190                 195

 Arg Leu Thr Thr Ala Leu Gln Glu Ser Ala Ala Ser Val Glu Gln
                 200                 205                 210

 Trp Lys Arg Gln Phe Ser Ile Cys Arg Asp Glu Asn Asp Arg Leu
                 215                 220                 225

 Arg Asn Lys Ile Asp Glu Leu Glu Glu Gln Cys Ser Glu Ile Asn
                 230                 235                 240

 Arg Glu Lys Glu Lys Asn Thr Gln Leu Lys Arg Arg Ile Glu Glu
                 245                 250                 255

 Leu Glu Ala Glu Leu Arg Glu Lys Glu Thr Glu Leu Lys Asp Leu
                 260                 265                 270

 Arg Lys Gln Ser Glu Ile Ile Pro Gln Leu Met Ser Glu Cys Glu
                 275                 280                 285

 Tyr Val Ser Glu Lys Leu Glu Ala Ala Glu Arg Asp Asn Gln Asn
                 290                 295                 300

 Leu Glu Asp Lys Val Arg Ser Leu Lys Thr Asp Ile Glu Glu Ser
                 305                 310                 315

 Lys Tyr Arg Gln Arg His Leu Lys Val Glu Leu Lys Ser Phe Leu
                 320                 325                 330

 Glu Val Leu Asp Gly Lys Ile Asp Asp Leu His Asp Phe Arg Arg
                 335                 340                 345

 Gly Leu Ser Lys Leu Gly Thr Asp Asn
                 350

<210> 3019
<211> 4134
<212> DNA
<213> Homo sapien

<400> 3019
 gccggaagct ggcgtactcc ggcagcgaaa gcggtgcaga cgggaggaag 50

 gcagctgagc ctgaggtgga ggtggaggtg taccggcggg actccaagaa 100

 gctgccaggc ctgggagacc ctgacatcga ctgggaggag agcgtctgcc 150

 tgaatctcat cctgcagaag ctggactaca tggtgacctg tgcggtgtgc 200

 acacgtgctg acggcgggga cattcacatc cataagaaga aatctcagca 250

 agtgttcgcg tcccccagta aacaccccat ggacagcaag ggggaggagt 300

 ccaagatcag ctaccccaac atcttcttca tgattgacag cttcgaggag 350

 gtgttcagcg acatgaccgt aggggaagga gagatggtct gtgtggagct 400

 ggtggctagt gacaaaacca acacgttcca gggggtcatc tttcagggct 450

 ccatccgcta cgaggcgctc aagaaggtgt atgacaaccg ggtgagcgtg 500

 gccgcccgca tggcacagaa gatgtcgttt ggcttctaca agtacagcaa 550

 catggagttt gtgcgcatga agggccccca gggcaagggc cacgccgaga 600

 tggcggtcag ccgagtgtct acaggtgaca catccccctg tgggactgaa 650

 gaggactcca gcccagcttc gcccatgcac gagcgggtga cctccttcag 700

 cacacccccc accccagaac ggaacaaccg gcctgccttc ttctccccat 750

 ccctcaagag gaaggtgccc cggaaccgga tcgctgagat gaagaagtcg 800

 cactcggcca acgacagcga ggagttcttc cgggaggacg acggtggagc 850

 cgatctgcac aatgcaacca acctgcggtc tcggtccctg tcgggcacag 900

 gacggtccct ggtcgggtcc tggctgaagc tgaacagagc agatggaaac 950

 ttccttctct atgcacactt aacctacgtc acgttgccgc tgcatcggat 1000

 tttaacagac atcctggaag ttcggcagaa gcccatcctg atgacctagc 1050

 cgcgtgcgga gcctgcgcag agccccggcc gggcccagcc ctcggagtgc 1100

 tgccaagtgc ctacctgtcc accgccaccg gggtctgcga tggcacgcca 1150

 gtgctggagc cgcagccagg cgaggccact cgactcccgg ggccggggcc 1200

 gactccacga acaccagccc aaactgaagt gcctcttccc tcccctgctg 1250

 gcgctgctcc gccctgtgcc ccccgcccat cgccccccac ccatctctgg 1300

 agagccctct gcacccaaag aggactagag atgccgagcg gccatgagag 1350

 agagcggaag gagcagctga tgcccagagc ggggccagag cggcgggtct 1400

 atgttcacgt ccccccagca gcaggcggaa ccacccagcc agggcactca 1450

 gtgcattgga ctgtccacat gttcttgagg aaagccggtg gaagattctg 1500

 gaatgccgtg cggatgaact tcagcgcccg agtcagtccc agctcatcct 1550

 ccccagttta ccactttgtt ctaataggag atgggaacac gagaagtttg 1600

 atggctttgc cctgggctgg gaatacctca cccacgccca gttccagaaa 1650

 ggcctccagc tgagcagacg gccccgatcc cgccagaacg gccttttgct 1700

 tccagccaaa gaacaccgcc aacacgcaca cctccaacct gggacatccc 1750

 acgctgggcc tcgcacggag gaacctgcag aatttggatt ctgagggtag 1800

 tcgggaggcc tcggtagcca ggcagaacag gatatctgcc aaagggtgtc 1850

 tgatgtgggg tggggctggc atcctcccag gaaggttcta ggtgggaccc 1900

 cgtcttctgg gggcgggggt gtcttttcat cttccctggt ttcctagaac 1950

 tcacttcctt tgacggcgtg tgttggtccc atctctcaga ccagctcact 2000

 gaggcagagg agttgctcag aggctcacat gggcaccccc attggttcgt 2050

 gtgagcagct gcccagcccc aggcctgccc tcggcctggt ccagcatgaa 2100

 ggcgtttcca tctgcaagga tgcacggtac cctccccgag agcaggcctg 2150

 tcccctaccc aactgggaat aaactggaag ctgggtctct ttgttgctat 2200

 gtttttttgt ttgaagttcc caggaatatt tgaggggttc cggtgatgtg 2250

 tttagggatc ttctctgtgg gggaaaagga agaggagggt cttgttctcc 2300

 catctgttta ttctttgggc tctgggaaca ggggactact ttggggcttt 2350

 ctccagactt ttgtatgttg ttattaaaag cgagctattg catttcattc 2400

 tgcctcagtt tgcccacctg tgaaatgggg ctgataccac ctacctcact 2450

 gaagtcccag ggttcaagtg tgtggctggg tcagggcgtg gtcacccgtc 2500

 attctgcata ggtcgggttg gatgttagac tcctgggatg ccctcctccc 2550

 ccctcgccct ttgtaataac ctaatctgag accgtgcttg gtggggggat 2600

 gtgaactttc tctctccccc agcagtgtct gctcaggcct gacagctcag 2650

 ctctgcacga tttcatgttc ctaaacccat gtcttagggc agcacagagc 2700

 caggtcatgt catgccccaa agtgtgggga cagagcctca gggagccccg 2750

 agcatggtcc agccccattt gagtgctctc cggggatgcc aaatgctgct 2800

 tccaagtttg agtccatgtg gctaaaatac acccatttct tcaggaactc 2850

 ttcccctggt tgttctgggg atcttgggag aaacacagcc ctgacagctc 2900

 gtccgtggga agatgaggca gtccaggttg tgaggagcac agcggcccgc 2950

 cctctgttct cagaggtgag gggcgggaga aggttgtctc ctctggggcc 3000

 agcatttggc caagctcgga ggcttggcca gcactgctgg atggctcaga 3050

 gcaagctggg ctccccgtct gtaagatggc aaaaatgctg cccccctcac 3100

 agggtgacca tgaggaccag tcacagtgat gtgtgaaagg gctcgctggt 3150

 cacagaaacg tgtacaaatc atgctatttt agagatcagc cctcaatttg 3200

 taaggcatgt gaacagggca cgcggtgggc tggtggtttc atagccgaca 3250

 cacagcgcct accatgtgca gctgcctgtc cgaccccatc ttacagacga 3300

 gaaaaccagc acacaggcac caaggaactg tccggaacta acagcagggg 3350

 ccggcgatgg gagtcaaacc caggcacgcg gcctggcctg catgctgagc 3400

 cacatggtgc tgtccggaca gatggacaga cactcggtgg agtctgcctt 3450

 tctcaggccc taaatccctc tccaaagggt acttgcgatg ccggatttaa 3500

 aacttgctca gagccactta gccacttgag aaccagacag taaggtgtta 3550

 ctcccaggtt tgtttttcca aagtaacaga tgacatgtgg aataaagtaa 3600

 tagagtaaca agtggcaggg ccagaaccag ggtccccaaa gtcctggtgt 3650

 tggcacattt gtacttcttg taagaccatc tttaattttt ctgggaacac 3700

 acctgccttt tgtgtaatgc ggggaagact aatgcatggt gacacctggt 3750

 tttcctcaac aggacacttg atcccaaaac ccctttaaga ccttaggttt 3800

 cctcagcgga aaactgtact ttaatcccaa acccccttta agacatattg 3850

 gggctgggcg cagtggctca cgcctgtaat cccagcactt tgggaggctg 3900

 agatgggtgg atcacctgag atcaggagtt caagaccagc ctgactaaca 3950

 tgctgaaacc ccatgtctac taaagataga aaaattagcc ggacatggtg 4000

 gcaggcacct gtaatcccag ctactcggaa ggctgaggaa ggagaatcac 4050

 ttgaacctag taggcagagg ttgcagtgag ccgagatcac gccattgcat 4100

 tctagcctgg gcaacgagag cgaaactctg tctc 4134

<210> 3020
<211> 348
<212> PRT
<213> Homo sapien

<400> 3020
 Arg Lys Leu Ala Tyr Ser Gly Ser Glu Ser Gly Ala Asp Gly Arg
   1               5                  10                  15

 Lys Ala Ala Glu Pro Glu Val Glu Val Glu Val Tyr Arg Arg Asp
                  20                  25                  30

 Ser Lys Lys Leu Pro Gly Leu Gly Asp Pro Asp Ile Asp Trp Glu
                  35                  40                  45

 Glu Ser Val Cys Leu Asn Leu Ile Leu Gln Lys Leu Asp Tyr Met
                  50                  55                  60

 Val Thr Cys Ala Val Cys Thr Arg Ala Asp Gly Gly Asp Ile His
                  65                  70                  75

 Ile His Lys Lys Lys Ser Gln Gln Val Phe Ala Ser Pro Ser Lys
                  80                  85                  90

 His Pro Met Asp Ser Lys Gly Glu Glu Ser Lys Ile Ser Tyr Pro
                  95                 100                 105

 Asn Ile Phe Phe Met Ile Asp Ser Phe Glu Glu Val Phe Ser Asp
                 110                 115                 120

 Met Thr Val Gly Glu Gly Glu Met Val Cys Val Glu Leu Val Ala
                 125                 130                 135

 Ser Asp Lys Thr Asn Thr Phe Gln Gly Val Ile Phe Gln Gly Ser
                 140                 145                 150

 Ile Arg Tyr Glu Ala Leu Lys Lys Val Tyr Asp Asn Arg Val Ser
                 155                 160                 165

 Val Ala Ala Arg Met Ala Gln Lys Met Ser Phe Gly Phe Tyr Lys
                 170                 175                 180

 Tyr Ser Asn Met Glu Phe Val Arg Met Lys Gly Pro Gln Gly Lys
                 185                 190                 195

 Gly His Ala Glu Met Ala Val Ser Arg Val Ser Thr Gly Asp Thr
                 200                 205                 210

 Ser Pro Cys Gly Thr Glu Glu Asp Ser Ser Pro Ala Ser Pro Met
                 215                 220                 225

 His Glu Arg Val Thr Ser Phe Ser Thr Pro Pro Thr Pro Glu Arg
                 230                 235                 240

 Asn Asn Arg Pro Ala Phe Phe Ser Pro Ser Leu Lys Arg Lys Val
                 245                 250                 255

 Pro Arg Asn Arg Ile Ala Glu Met Lys Lys Ser His Ser Ala Asn
                 260                 265                 270

 Asp Ser Glu Glu Phe Phe Arg Glu Asp Asp Gly Gly Ala Asp Leu
                 275                 280                 285

 His Asn Ala Thr Asn Leu Arg Ser Arg Ser Leu Ser Gly Thr Gly
                 290                 295                 300

 Arg Ser Leu Val Gly Ser Trp Leu Lys Leu Asn Arg Ala Asp Gly
                 305                 310                 315

 Asn Phe Leu Leu Tyr Ala His Leu Thr Tyr Val Thr Leu Pro Leu
                 320                 325                 330

 His Arg Ile Leu Thr Asp Ile Leu Glu Val Arg Gln Lys Pro Ile
                 335                 340                 345

 Leu Met Thr


<210> 3021
<211> 1670
<212> DNA
<213> Homo sapien

<400> 3021
 ccaaccacaa gcaccaaagc agaggggcag gcagcacacc acccagcagc 50

 cagagcacca gcccagccat ggtccttgag gtgagtgacc accaagtgct 100

 aaatgacgcc gaggttgccg ccctcctgga gaacttcagc tcttcctatg 150

 actatggaga aaacgagagt gactcgtgct gtacctcccc gccctgccca 200

 caggacttca gcctgaactt cgaccgggcc ttcctgccag ccctctacag 250

 cctcctcttt ctgctggggc tgctgggcaa cggcgcggtg gcagccgtgc 300

 tgctgagccg gcggacagcc ctgagcagca ccgacacctt cctgctccac 350

 ctagctgtag cagacacgct gctggtgctg acactgccgc tctgggcagt 400

 ggacgctgcc gtccagtggg tctttggctc tggcctctgc aaagtggcag 450

 gtgccctctt caacatcaac ttctacgcag gagccctcct gctggcctgc 500

 atcagctttg accgctacct gaacatagtt catgccaccc agctctaccg 550

 ccgggggccc ccggcccgcg tgaccctcac ctgcctggct gtctgggggc 600

 tctgcctgct tttcgccctc ccagacttca tcttcctgtc ggcccaccac 650

 gacgagcgcc tcaacgccac ccactgccaa tacaacttcc cacaggtggg 700

 ccgcacggct ctgcgggtgc tgcagctggt ggctggcttt ctgctgcccc 750

 tgctggtcat ggcctactgc tatgcccaca tcctggccgt gctgctggtt 800

 tccaggggcc agcggcgcct gcgggccatg cggctggtgg tggtggtcgt 850

 ggtggccttt gccctctgct ggacccccta tcacctggtg gtgctggtgg 900

 acatcctcat ggacctgggc gctttggccc gcaactgtgg ccgagaaagc 950

 agggtagacg tggccaagtc ggtcacctca ggcctgggct acatgcactg 1000

 ctgcctcaac ccgctgctct atgcctttgt aggggtcaag ttccgggagc 1050

 ggatgtggat gctgctcttg cgcctgggct gccccaacca gagagggctc 1100

 cagaggcagc catcgtcttc ccgccgggat tcatcctggt ctgagacctc 1150

 agaggcctcc tactcgggct tgtgaggccg gaatccgggc tcccctttcg 1200

 cccacagtct gacttccccg cattccaggc tcctccctcc ctctgccggc 1250

 tctggctctc cccaatatcc tcgctcccgg gactcactgg cagccccagc 1300

 accaccaggt ctcccgggaa gccaccctcc cagctctgag gactgcacca 1350

 ttgctgctcc ttagctgcca agccccatcc tgccgcccga ggtggctgcc 1400

 tggagcccca ctgcccttct catttggaaa ctaaaacttc atcttcccca 1450

 agtgcgggga gtacaaggca tggcgtagag ggtgctgccc catgaagcca 1500

 cagcccaggc ctccagctca gcagtgactg tggccatggt ccccaagacc 1550

 tctatatttg ctcttttatt tttatgtcta aaatcctgct taaaactttt 1600

 caataaacaa gatcgtcagg accaaaaaaa aaaaaaaaaa aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaaa 1670

<210> 3022
<211> 368
<212> PRT
<213> Homo sapien

<400> 3022
 Met Val Leu Glu Val Ser Asp His Gln Val Leu Asn Asp Ala Glu
   1               5                  10                  15

 Val Ala Ala Leu Leu Glu Asn Phe Ser Ser Ser Tyr Asp Tyr Gly
                  20                  25                  30

 Glu Asn Glu Ser Asp Ser Cys Cys Thr Ser Pro Pro Cys Pro Gln
                  35                  40                  45

 Asp Phe Ser Leu Asn Phe Asp Arg Ala Phe Leu Pro Ala Leu Tyr
                  50                  55                  60

 Ser Leu Leu Phe Leu Leu Gly Leu Leu Gly Asn Gly Ala Val Ala
                  65                  70                  75

 Ala Val Leu Leu Ser Arg Arg Thr Ala Leu Ser Ser Thr Asp Thr
                  80                  85                  90

 Phe Leu Leu His Leu Ala Val Ala Asp Thr Leu Leu Val Leu Thr
                  95                 100                 105

 Leu Pro Leu Trp Ala Val Asp Ala Ala Val Gln Trp Val Phe Gly
                 110                 115                 120

 Ser Gly Leu Cys Lys Val Ala Gly Ala Leu Phe Asn Ile Asn Phe
                 125                 130                 135

 Tyr Ala Gly Ala Leu Leu Leu Ala Cys Ile Ser Phe Asp Arg Tyr
                 140                 145                 150

 Leu Asn Ile Val His Ala Thr Gln Leu Tyr Arg Arg Gly Pro Pro
                 155                 160                 165

 Ala Arg Val Thr Leu Thr Cys Leu Ala Val Trp Gly Leu Cys Leu
                 170                 175                 180

 Leu Phe Ala Leu Pro Asp Phe Ile Phe Leu Ser Ala His His Asp
                 185                 190                 195

 Glu Arg Leu Asn Ala Thr His Cys Gln Tyr Asn Phe Pro Gln Val
                 200                 205                 210

 Gly Arg Thr Ala Leu Arg Val Leu Gln Leu Val Ala Gly Phe Leu
                 215                 220                 225

 Leu Pro Leu Leu Val Met Ala Tyr Cys Tyr Ala His Ile Leu Ala
                 230                 235                 240

 Val Leu Leu Val Ser Arg Gly Gln Arg Arg Leu Arg Ala Met Arg
                 245                 250                 255

 Leu Val Val Val Val Val Val Ala Phe Ala Leu Cys Trp Thr Pro
                 260                 265                 270

 Tyr His Leu Val Val Leu Val Asp Ile Leu Met Asp Leu Gly Ala
                 275                 280                 285

 Leu Ala Arg Asn Cys Gly Arg Glu Ser Arg Val Asp Val Ala Lys
                 290                 295                 300

 Ser Val Thr Ser Gly Leu Gly Tyr Met His Cys Cys Leu Asn Pro
                 305                 310                 315

 Leu Leu Tyr Ala Phe Val Gly Val Lys Phe Arg Glu Arg Met Trp
                 320                 325                 330

 Met Leu Leu Leu Arg Leu Gly Cys Pro Asn Gln Arg Gly Leu Gln
                 335                 340                 345

 Arg Gln Pro Ser Ser Ser Arg Arg Asp Ser Ser Trp Ser Glu Thr
                 350                 355                 360

 Ser Glu Ala Ser Tyr Ser Gly Leu
                 365

<210> 3023
<211> 5932
<212> DNA
<213> Homo sapien

<400> 3023
 ggggcactga ggagcggcgc ccgcggggca gcgaggagcc cgatgcaggg 50

 ttctgcgcgt catttccggt cccgcgggcg ccccgtgaag cccacctgga 100

 tccgccagcg ctgtgccact ccccagtgcc gagctccgag ctgtctccgc 150

 ggcctcgcgc ccggcccctc caccgcgcac ctcttaggcc ccgcccgcca 200

 gcgtcccttt gttgtgaagg cgccggggcc tagcgctatg cctgcggcgg 250

 agactgcatc aggctctcgc gtctgcttct gcgctttgcc tgggagaggc 300

 cctggtggcc tcgttcctgg cgcccggagt ccctgctgcg gccccacccc 350

 cgggcggtca cggtgaccca tgctgcccag cctggaggta aaatcgttcg 400

 tggctgtggc ttcagcatgt cgtcctcggt gaaaacccca gcactggaag 450

 agctggttcc tggctccgaa gagaagccga aaggcaggtc gcctctcagc 500

 tggggctctc tgtttggtca ccgaagtgag aagattgttt ttgccaagag 550

 cgacggcggc acagatgaga acgtactgac cgtcaccatc acggagacca 600

 cggtcatcga gtcagacttg ggtgtgtgga gctcgcgggc gctgctctac 650

 ctcacgctgt ggttcttctt cagcttctgc acgctcttcc tcaacaagta 700

 catcctgtcc ctgctgggag gcgagcccag catgctaggt gcggtgcaga 750

 tgctgtccac cacggttatc gggtgtgtga aaaccctcgt tccttgctgt 800

 ttgtatcagc acaaggcccg gctttcctac ccacccaact tccttatgac 850

 gatgctgttt gtgggtctga tgaggtttgc aactgtggtt ttgggtttgg 900

 tcagcctgaa aaatgtggcg gtttcgtttg ctgagacggt gaagagctcc 950

 gcccccatct tcacggtgat catgtctcgg atgattctgg gggagtacac 1000

 agggctgctg gtcaacctct ccctcatccc agtcatgggc gggctggcgc 1050

 tgtgcacggc cactgagatc agcttcaatg tcctggggtt ctcggccgca 1100

 ctgtccacca acatcatgga ctgtttgcaa aatgtttttt caaaaaagct 1150

 gctcagcggg gacaaataca ggttctcggc cccggagctg cagttctaca 1200

 ccagcgccgc tgcggtggcc atgctcgtcc cggcccgggt tttctttacg 1250

 gacgtcccag tgatcgggag gagcgggaag agcttcagct acaaccagga 1300

 cgtggtgctg ctgcttctga cagacggagt cctgttccac cttcagagcg 1350

 tcacggcgta cgccctcatg gggaaaatct ccccggtgac tttcagcgtc 1400

 gccagcaccg tgaaacatgc cttgtccatc tggctcagcg taatcgtttt 1450

 cggcaacaag atcaccagct tgtcggccgt tggcacagcc ctggtgaccg 1500

 ttggggtcct gctctacaac aaagccaggc aacaccagca ggaggcgctg 1550

 cagagcctgg ctgcagccac tggccgggcc ccagacgaca cagtggagcc 1600

 gctgcttcca caggacccca ggcagcatcc ctgagagcag gaagctgcca 1650

 gctgctgctg tcctcgtgac actgcatccc ccagaaatgg gcagggacgc 1700

 cctcctccat ggccctgctg gggtgcagga catggggagc taagttggcc 1750

 attgcctgcg gctttctcgg tttgtcggtg aagaccagca gaaactcaaa 1800

 ctggggattc caggtatcag cttcctggag tagacaccag accagtagct 1850

 gactgtgtcc gccgagccca tccccgtgta atgtgaaaac agcctctgag 1900

 gctcccatgc tgggggtgcc cacttcctct ctgggcgaca ccccagggtc 1950

 caccgggagc cagaggtggg tccagtgcca acgagagccg ctccctgcca 2000

 cagccaagag agccctcggc ttcccacacc agccatcgaa ggccctgagg 2050

 ccctggaccg gcggcagact ggccctgggc atgaggccac agagcagggc 2100

 cgaagggagg ggacagaggg ccctggaagg aagggtctcc tgctgccacg 2150

 gtgggcactc agaacttctc cccacctgac ccagggctgt gggcatcctc 2200

 agactatccc agaggcatcg caagcctcaa gctgcagcat tgcacggcac 2250

 tcaagggcta tgaccacgga ggccgttcag tcgcttctgt ttagaggaag 2300

 gccccctacc tcttccacac cctgccctcc tatcccttcc acaccctggg 2350

 ctgcatgagc tccccgcaac cccagggcac cctgccctcc tacctgtggg 2400

 ggtttccagc cctgaggttg aggacaaacc tctcgtgttt aacttgggag 2450

 gagatgtgta cgttcctttt cttttttgga ctctgagtat gaggcaggct 2500

 gttctgaggt ccccgtgggg tgagcctgtc tgtcctccct cagagcccac 2550

 cgttcctatc atcatctagc acctgtccgg ttccccacgt gagccttggg 2600

 caggacgctg cagtgttgat ggtttgggtt acgtggcgtt tacctgggcg 2650

 ccgtccttgc tgaaaaagga aacgtccaca ctgaatgttt ctggggcgcg 2700

 tggtgtgtgt caggcgccca ccctgtccca ctctccccaa gggacagtag 2750

 tacggcacac tggggccacc agccagctca actcatcctc ctgtgtcacg 2800

 cacccccgag ggcgcaggag gcctgaggag tggctactgg agccgtgtgt 2850

 taggcagagg cttctgacca tgtctgagct ctttaccccc aatctcgcaa 2900

 ccggcggatt cccatgcccg gtgcagcctg ttgccagcca gcctttgaga 2950

 cccagagctc cagggcttgt cagaggcagc atggggctcc agtggtcccg 3000

 agtctcattt ccctgcctgc tctttaggcc tttggcaccc atggtcactt 3050

 cactggtttt ccatttggct tctcacctgg gaaatacaaa aatagcccct 3100

 cctgaagata aaatcgttca gaaacagagc aataattctg actcattaac 3150

 ttctacctac tcaaaaaagt ctgccatgat gatggaccga agtgaggctt 3200

 tttaacccac aagtaacctt tttatttttt tgagacggtc ttgctctgtc 3250

 acccaggctg gagtgcagtg gcatgatctt ggctcgctgc agcctcgact 3300

 tcctgggctc aagtgatcca cctcagcctc ccatgtggct ggaaccgcag 3350

 gcacgtgcca ccatgcctgg ctattttttt gttgagctgg gctctcgctt 3400

 tgttgcccag gctggtcttg aactcctcgg ctcaagcaat ccttcccact 3450

 cagcctcctg tagtgtcgag aatataggcg tgggctacta cacctgcttc 3500

 agccgcttct ataaaaccgc tgacctgtgt gtggaggaca ggccaggtgt 3550

 gtgctcactg cgctgcgaag atgttttgtc acgtgacttt ccctgggttt 3600

 ccatttcttt ttttctgctt tcctcaaaaa ctaatagaag accggctgcg 3650

 gtagctcagg cctctagtcc cagcactttg ggaggctgca gatggcggat 3700

 cacaaggcca ggagttcgag accagcctgg ccaacatgat gaaaccctgt 3750

 ctctaccaaa aatacaaaaa ttagctgggt gtgatggtgg gtgcctgtgg 3800

 tctcagctac tcaggaggct gaggcaggag aattgtttga gccccagagg 3850

 cggaggttgc agtgagccaa gatcgtgcca ttgcactcca gcctgggcaa 3900

 cagggcaaga ttccgtctca aaaacaaaca ctattagaaa atgctctgga 3950

 ggtggcgggg agttgttgat ttgtgaggac agattgaaag caactcccag 4000

 ggtggccttg tccacctccc catcgagaat atggctgccg gcctctttga 4050

 agattgtggt ctggcataag gagaggtgca ggcgcctggt tctgagcacc 4100

 ttggaatttc cagccgcaca gcatctggtg ccctcccctc caccctcaca 4150

 aggagctgcc atcctgtttg gattttctgt ttgtggacca gaaacaaacg 4200

 tttttccaaa ggattagcaa ataggttgat ttcctgtgta acgctgctct 4250

 ggggcctctt cctcatcctg gcagaaggag cctggagccc atgaggcagc 4300

 cagcactgtg cccttgctca gtcgtgctgt cccctccctc tccctcagtc 4350

 tcttctccat gcccaagtca gtttccagcc gctggtcttc atggcattcc 4400

 cagcacagct ggacaccaag aggcaaaacc caaggcctgg cttggccgtg 4450

 ttaacgattg tacagacatt tttttaaata actttgtgta atacttttct 4500

 agaatagtaa gttcttgttg aactgtcaca gatgagcttc taggaacaca 4550

 ccgggtgtgg ttacttccac tgggtgtgtc catggtcgtg gtctgtgcct 4600

 ttgtaaacaa acagaacact tgaaccacct tccgaattgg gtcatcggct 4650

 tctttacatt gatacttaga gatttgcagc tctctaactt tcaaggaaac 4700

 ttcccctact gaaaggcata aaaaggttaa aaaagaaaat ccgagagtcc 4750

 caattccctg tataacagca ttaaaataat ctgcctgcct ggaaagatga 4800

 gaacactgtt gcacaaccca aaatgtgttt ttaatttgtg aaaaattacc 4850

 atggtgagtc agacagtcat tttaaacagc tgaacagaga ctatcatcag 4900

 caaatagagc tcagctttgt agctgccttt aaaatccttg tcccaaatcc 4950

 ggtgagctct gcttgctgcc gccgcgctcc tgggtgatca ctcagacggg 5000

 tcagtgggaa taacgggcca acaagacagc tttttacatg tgtccaaagg 5050

 atggcctttc gaaggcctgg aagtatttca ctgttggaag aagtaaacaa 5100

 gaatgacatt ccagatggaa atagaattct ctctcttgcc tttgaccaac 5150

 atggtactaa ggggtttctt ctttcccaat gtatgtacgt gccctgctgg 5200

 gggccttact ttatagaatg agagcatccg agcttcccta atgaatctgg 5250

 ctagttctgt gtctggctga ggatacagga gtgggacatc cactctcgga 5300

 tccctcagag cacagaaacc ttcagctttg ctgtctctga agtatttcct 5350

 ccagtttccc tgcgggcccc tatgtttgag tttgatggct gctggatcct 5400

 cactcaacga aaactcggtt ggaaactgtt ccgcctggca gtcctttttt 5450

 gttgttttcc atctcatttc ccttccatct gaaagtggca ttcagctgac 5500

 ttgctcattt agactgttca cggagtctga atctgccaac gtggtgttgg 5550

 aggctccacc ttgaaaaggg ccacagtcag ggcaactttc cccatacagg 5600

 aaaacttgaa aattacatca acagtctacg tcacagccaa attatatttc 5650

 ctttatacca aacaaaacta tggagaacta aaagtacatc acacaaaacg 5700

 tttatagtgt tttgcatgtg acctatttca gtatttatat aactagatta 5750

 gtgctttcta gcaaacggtt ctgttaatta gcgagtcact gttgattctg 5800

 ctgtggtggt aagttgatac cgtgtaacta atcccgtgga tgcctcctcg 5850

 ttatttttgt ccaaacgaag cagccgtggt agtagctgtc tatgattctt 5900

 gctcagcaaa gtaaaataaa tgttaaatat gg 5932

<210> 3024
<211> 466
<212> PRT
<213> Homo sapien

<400> 3024
 Arg Tyr Ala Cys Gly Gly Asp Cys Ile Arg Leu Ser Arg Leu Leu
   1               5                  10                  15

 Leu Arg Phe Ala Trp Glu Arg Pro Trp Trp Pro Arg Ser Trp Arg
                  20                  25                  30

 Pro Glu Ser Leu Leu Arg Pro His Pro Arg Ala Val Thr Val Thr
                  35                  40                  45

 His Ala Ala Gln Pro Gly Gly Lys Ile Val Arg Gly Cys Gly Phe
                  50                  55                  60

 Ser Met Ser Ser Ser Val Lys Thr Pro Ala Leu Glu Glu Leu Val
                  65                  70                  75

 Pro Gly Ser Glu Glu Lys Pro Lys Gly Arg Ser Pro Leu Ser Trp
                  80                  85                  90

 Gly Ser Leu Phe Gly His Arg Ser Glu Lys Ile Val Phe Ala Lys
                  95                 100                 105

 Ser Asp Gly Gly Thr Asp Glu Asn Val Leu Thr Val Thr Ile Thr
                 110                 115                 120

 Glu Thr Thr Val Ile Glu Ser Asp Leu Gly Val Trp Ser Ser Arg
                 125                 130                 135

 Ala Leu Leu Tyr Leu Thr Leu Trp Phe Phe Phe Ser Phe Cys Thr
                 140                 145                 150

 Leu Phe Leu Asn Lys Tyr Ile Leu Ser Leu Leu Gly Gly Glu Pro
                 155                 160                 165

 Ser Met Leu Gly Ala Val Gln Met Leu Ser Thr Thr Val Ile Gly
                 170                 175                 180

 Cys Val Lys Thr Leu Val Pro Cys Cys Leu Tyr Gln His Lys Ala
                 185                 190                 195

 Arg Leu Ser Tyr Pro Pro Asn Phe Leu Met Thr Met Leu Phe Val
                 200                 205                 210

 Gly Leu Met Arg Phe Ala Thr Val Val Leu Gly Leu Val Ser Leu
                 215                 220                 225

 Lys Asn Val Ala Val Ser Phe Ala Glu Thr Val Lys Ser Ser Ala
                 230                 235                 240

 Pro Ile Phe Thr Val Ile Met Ser Arg Met Ile Leu Gly Glu Tyr
                 245                 250                 255

 Thr Gly Leu Leu Val Asn Leu Ser Leu Ile Pro Val Met Gly Gly
                 260                 265                 270

 Leu Ala Leu Cys Thr Ala Thr Glu Ile Ser Phe Asn Val Leu Gly
                 275                 280                 285

 Phe Ser Ala Ala Leu Ser Thr Asn Ile Met Asp Cys Leu Gln Asn
                 290                 295                 300

 Val Phe Ser Lys Lys Leu Leu Ser Gly Asp Lys Tyr Arg Phe Ser
                 305                 310                 315

 Ala Pro Glu Leu Gln Phe Tyr Thr Ser Ala Ala Ala Val Ala Met
                 320                 325                 330

 Leu Val Pro Ala Arg Val Phe Phe Thr Asp Val Pro Val Ile Gly
                 335                 340                 345

 Arg Ser Gly Lys Ser Phe Ser Tyr Asn Gln Asp Val Val Leu Leu
                 350                 355                 360

 Leu Leu Thr Asp Gly Val Leu Phe His Leu Gln Ser Val Thr Ala
                 365                 370                 375

 Tyr Ala Leu Met Gly Lys Ile Ser Pro Val Thr Phe Ser Val Ala
                 380                 385                 390

 Ser Thr Val Lys His Ala Leu Ser Ile Trp Leu Ser Val Ile Val
                 395                 400                 405

 Phe Gly Asn Lys Ile Thr Ser Leu Ser Ala Val Gly Thr Ala Leu
                 410                 415                 420

 Val Thr Val Gly Val Leu Leu Tyr Asn Lys Ala Arg Gln His Gln
                 425                 430                 435

 Gln Glu Ala Leu Gln Ser Leu Ala Ala Ala Thr Gly Arg Ala Pro
                 440                 445                 450

 Asp Asp Thr Val Glu Pro Leu Leu Pro Gln Asp Pro Arg Gln His
                 455                 460                 465

 Pro


<210> 3025
<211> 1918
<212> DNA
<213> Homo sapien

<400> 3025
 gggtagtaga acaatgggat tatgctgtca caaaaaccaa agaaaaaaca 50

 taatttctta aatcatggtc tgtcactgaa tctggttata aaaccttatc 100

 ttgcactaga aggatctgta gcttttccag ctgagaatgg ggttcaggat 150

 accgaatcaa cacaagaaaa gagagaaact ggggatgaag aaaactcagc 200

 taaatttcct gtaggaagga gagattttga cacactcagc tgtatgctgg 250

 gaagagtcta ccaatcttgc tggcaagtct gattcttttt ttgatatgga 300

 cctgttggtc tatgtcatct tttcagaaga aaagcattta attgccaatg 350

 ggaggagaag cccataatgt tactgtaact tgggtattat gttaaatgtc 400

 tggtttaaaa gaaagtagcg ttaagataga tcagtaacca aaatcatagg 450

 ctttttctgt gcattgaact ttgtgaaaat tctgtataat tatgacttac 500

 tagtattttt gaacaatgct taacatacta accttacata cactctagac 550

 caaaataagg catcataatt tacaccttaa tctcaaaaat taagcatgtc 600

 tttggtgaat ggttttatat atacataaac ctaaagcata taagacaaaa 650

 atttatgttt ggagcctgtg ttctgtaaag agaaggttga tttgtctttt 700

 agctatcgta tttggagtgg aactataata caaatgtata atattctttt 750

 tttttttttt tttttgagat ggagtctcac tctgttgccc aggctggagt 800

 gcaatggcac gatctcggct cactgaaacc tctgcctccc gggttcaagc 850

 aatttcctgc ctcagcctca tgaatagctg ggattacagg tgcccaccac 900

 catgcctggc tagtttttgt atttttagta gaggcaaggt ttcaccatct 950

 tggtcaagtt ggtctggaac tcctgacctc gtgatccacc tgcctcggct 1000

 tcccaaagtg ctgggattac aggcgtgcac cactgagtcc agcctatatt 1050

 cttgtttatc agttcaaaaa tgttctgctc tgtttttgac tctttaaaaa 1100

 taacttagat tcaaatttat agtagaaaga aaaaaaaatc tttcagataa 1150

 gaggtgttct ccagaatgga ggaactactt ggcatgtaag aaatagcgtc 1200

 agtgtcctaa tgcatattgt gactgtttgc atatacttct gtttgtaaaa 1250

 atatcagttt tacttttcag aggatttgta agaaacattt aaattttcat 1300

 tgaaataaat gacaagtcat actgccactt aaaaaaaaaa agacctttgt 1350

 caaggagagt gcagtcaacc agtaaattgc agattctcag aatgtttatt 1400

 gacgtactga ttattcattc tgttatactc taacatctgt atatttttac 1450

 cagtattctc agaccacttc taccaaaaca taaatctgtg attgtgatct 1500

 ctgaaagtca gtccttttat ctactcaata actgatctga taatgtcaac 1550

 ttttgaaaac agatagttat gactcaaggc tttgagaatg taaagagacc 1600

 accttcactt gttgagaaat ggtacgattt cacgttatca gtgcagttcc 1650

 gttctcgggg gaaagcccat ccgtactacc aggagactgg atccgcaaag 1700

 tagacacttg gtctcatgaa gccactgctg ggctccagag agaagggaaa 1750

 actaagaggt tttaaaaccc ctaccctcct tggtttacct ccatcattaa 1800

 aaaacaacaa tgacaacgac aacaaaaaac aaaactaaaa cgacttatta 1850

 tttattaatt atgttgtggc agacaatatg ctgaacatta gacataatta 1900

 aatcttttta aaaattga 1918

<210> 3026
<211> 86
<212> PRT
<213> Homo sapien

<400> 3026
 Met Leu Ser Gln Lys Pro Lys Lys Lys His Asn Phe Leu Asn His
   1               5                  10                  15

 Gly Leu Ser Leu Asn Leu Val Ile Lys Pro Tyr Leu Ala Leu Glu
                  20                  25                  30

 Gly Ser Val Ala Phe Pro Ala Glu Asn Gly Val Gln Asp Thr Glu
                  35                  40                  45

 Ser Thr Gln Glu Lys Arg Glu Thr Gly Asp Glu Glu Asn Ser Ala
                  50                  55                  60

 Lys Phe Pro Val Gly Arg Arg Asp Phe Asp Thr Leu Ser Cys Met
                  65                  70                  75

 Leu Gly Arg Val Tyr Gln Ser Cys Trp Gln Val
                  80                  85

<210> 3027
<211> 1822
<212> DNA
<213> Homo sapien

<400> 3027
 ccgctttagt gcgctcgccg tcggctctac ctgcgtgctt tagctccttc 50

 tcgcctgatc cttctgtctc tcccaacccc ggacacccgg cttcgactgg 100

 ttatatcttc ggtgttcttt tcctctcttc ttctttcgcg gttcagcatg 150

 caggaaaaag acgcctcctc acaaggtttc ctgccacact tccaacattt 200

 cgccacgcag gcgatccatg tgggccagga tccagagcaa tggacctcca 250

 gggctgtagt gccccccatc tcactgtcca ccacgttcaa gcaaggggcg 300

 cctggccagc actcgggttt tgaatatagc cgttctggaa atcccactag 350

 gaattgcctt gaaaaagcag tggcagcact ggatggggct aagtactgtt 400

 tggcctttgc ttcaggttta gcagccactg taactattac ccatctttta 450

 aaagcaggag accaaattat ttgtatggat gatgtgtatg gaggtacaaa 500

 caggtacttc aggcaagtgg catctgaatt tggattaaag atttcttttg 550

 ttgattgttc caaaatcaaa ttactagagg cagcaattac accagaaacc 600

 aagcttgttt ggatcgaaac ccccacaaac cccacccaga aggtgattga 650

 cattgaaggc tgtgcacata ttgtccataa gcatggagac attattttgg 700

 tcgtggataa cacttttatg tcaccatatt tccagcgccc tttggctctg 750

 ggagctgata tttctatgta ttctgcaaca aaatacatga atggccacag 800

 tgatgttgta atgggcctgg tgtctgttaa ttgtgaaagc cttcataata 850

 gacttcgttt cttgcaaaac tctcttggag cagttccatc tcctattgat 900

 tgttacctct gcaatcgagg tctgaagact ctacatgtcc gaatggaaaa 950

 gcatttcaaa aacggaatgg cagttgccca gttcctggaa tctaatcctt 1000

 gggtagaaaa ggttatttat cctgggctgc cctctcatcc acagcatgag 1050

 ttggtgaagc gtcagtgtac aggttgtaca gggatggtca ccttttatat 1100

 taagggcact cttcagcatg ctgagatttt cctcaagaac ctaaagctat 1150

 ttactctggc cgagagcttg ggaggattcg aaagccttgc tgagcttccg 1200

 gcaatcatga ctcatgcatc agttcttaag aatgacagag atgtccttgg 1250

 aattagtgac acactgattc gactttctgt gggcttagag gatgaggaag 1300

 acctactgga agatctagat caagctttga aggcagcaca ccctccaagt 1350

 ggaagtcaca gctagtattc cagagctgct attagaagct gcttcctgtg 1400

 aagatcaaat cttcctgagt aattaaatgg accaacaatg agcctttgca 1450

 aaattttcaa gcggaaattt taaggcacct cattatcttt cataactgta 1500

 attttcttag ggatcatctc tgttaaaaag ttttctgtat gtcatgttat 1550

 aattacaggt caattctgtt aatatctttt tgttaatttt gctctatgtt 1600

 tgcctctgaa ggaggtgaga tttgtgctac tttgggagat tatgttcttt 1650

 tttcatgtct aagatttatt ttgatcatgt ttataatata atggtaattc 1700

 atttttgatg ttttgtgaag aatttaaatt taaacgaatg ttcttaaatc 1750

 aagtgtgatt tttttgcata tcattgaaaa gaacattaaa agcaatggtt 1800

 tacacttaaa aaaaaaaaaa aa 1822

<210> 3028
<211> 405
<212> PRT
<213> Homo sapien

<400> 3028
 Met Gln Glu Lys Asp Ala Ser Ser Gln Gly Phe Leu Pro His Phe
   1               5                  10                  15

 Gln His Phe Ala Thr Gln Ala Ile His Val Gly Gln Asp Pro Glu
                  20                  25                  30

 Gln Trp Thr Ser Arg Ala Val Val Pro Pro Ile Ser Leu Ser Thr
                  35                  40                  45

 Thr Phe Lys Gln Gly Ala Pro Gly Gln His Ser Gly Phe Glu Tyr
                  50                  55                  60

 Ser Arg Ser Gly Asn Pro Thr Arg Asn Cys Leu Glu Lys Ala Val
                  65                  70                  75

 Ala Ala Leu Asp Gly Ala Lys Tyr Cys Leu Ala Phe Ala Ser Gly
                  80                  85                  90

 Leu Ala Ala Thr Val Thr Ile Thr His Leu Leu Lys Ala Gly Asp
                  95                 100                 105

 Gln Ile Ile Cys Met Asp Asp Val Tyr Gly Gly Thr Asn Arg Tyr
                 110                 115                 120

 Phe Arg Gln Val Ala Ser Glu Phe Gly Leu Lys Ile Ser Phe Val
                 125                 130                 135

 Asp Cys Ser Lys Ile Lys Leu Leu Glu Ala Ala Ile Thr Pro Glu
                 140                 145                 150

 Thr Lys Leu Val Trp Ile Glu Thr Pro Thr Asn Pro Thr Gln Lys
                 155                 160                 165

 Val Ile Asp Ile Glu Gly Cys Ala His Ile Val His Lys His Gly
                 170                 175                 180

 Asp Ile Ile Leu Val Val Asp Asn Thr Phe Met Ser Pro Tyr Phe
                 185                 190                 195

 Gln Arg Pro Leu Ala Leu Gly Ala Asp Ile Ser Met Tyr Ser Ala
                 200                 205                 210

 Thr Lys Tyr Met Asn Gly His Ser Asp Val Val Met Gly Leu Val
                 215                 220                 225

 Ser Val Asn Cys Glu Ser Leu His Asn Arg Leu Arg Phe Leu Gln
                 230                 235                 240

 Asn Ser Leu Gly Ala Val Pro Ser Pro Ile Asp Cys Tyr Leu Cys
                 245                 250                 255

 Asn Arg Gly Leu Lys Thr Leu His Val Arg Met Glu Lys His Phe
                 260                 265                 270

 Lys Asn Gly Met Ala Val Ala Gln Phe Leu Glu Ser Asn Pro Trp
                 275                 280                 285

 Val Glu Lys Val Ile Tyr Pro Gly Leu Pro Ser His Pro Gln His
                 290                 295                 300

 Glu Leu Val Lys Arg Gln Cys Thr Gly Cys Thr Gly Met Val Thr
                 305                 310                 315

 Phe Tyr Ile Lys Gly Thr Leu Gln His Ala Glu Ile Phe Leu Lys
                 320                 325                 330

 Asn Leu Lys Leu Phe Thr Leu Ala Glu Ser Leu Gly Gly Phe Glu
                 335                 340                 345

 Ser Leu Ala Glu Leu Pro Ala Ile Met Thr His Ala Ser Val Leu
                 350                 355                 360

 Lys Asn Asp Arg Asp Val Leu Gly Ile Ser Asp Thr Leu Ile Arg
                 365                 370                 375

 Leu Ser Val Gly Leu Glu Asp Glu Glu Asp Leu Leu Glu Asp Leu
                 380                 385                 390

 Asp Gln Ala Leu Lys Ala Ala His Pro Pro Ser Gly Ser His Ser
                 395                 400                 405

<210> 3029
<211> 1186
<212> DNA
<213> Homo sapien

<400> 3029
 gttcacttca cagtacagag tcctgaaaat aaagaagaaa attttttttt 50

 atctagaaaa agaaccaaac atgtcacttt ctagcctgct gaaggtggtc 100

 acagcttcac tgtggctagg acctggcatt gcccagaaga taactcaaac 150

 ccaaccagga atgttcgtgc aggaaaagga ggctgtgact ctggactgca 200

 catatgacac cagtgatcca agttatggtc tattctggta caagcagccc 250

 agcagtgggg aaatgatttt tcttatttat caggggtctt atgaccagca 300

 aaatgcaaca gaaggtcgct actcattgaa tttccagaag gcaagaaaat 350

 ccgccaacct tgtcatctcc gcttcacaac tgggggactc agcaatgtat 400

 ttctgtgcaa tgagagcggt gtacaccgat aaactcatct ttggaaaagg 450

 aacccgtgtg actgtggaac caagaagtca gcctcatacc aaaccatccg 500

 tttttgtcat gaaaaatgga acaaatgtcg cttgtctggt gaaggaattc 550

 taccccaagg atataagaat aaatctcgtg tcatccaaga agataacaga 600

 gtttgatcct gctattgtca tctctcccag tgggaagtac aatgctgtca 650

 agcttggtaa atatgaagat tcaaattcag tgacatgttc agttcaacac 700

 gacaataaaa ctgtgcactc cactgacttt gaagtgaaga cagattctac 750

 agatcacgta aaaccaaagg aaactgaaaa cacaaagcaa ccttcaaaga 800

 gctgccataa acccaaagcc atagttcata ccgagaaggt gaacatgatg 850

 tccctcacag tgcttgggct acgaatgctg tttgcaaaga ctgttgccgt 900

 caattttctc ttgactgcca agttattttt cttgtaaggc tgactggcat 950

 gaggaagcta cactcctgaa gaaaccaaag gcttacaaaa atgcatctcc 1000

 ttggcttctg acttctttgt gattcaagtt gacctgtcat agccttgtta 1050

 aaatggctgc tagccaaacc actttttctt caaagacaac aaacccagct 1100

 catcctccag cttgatggga agacaaaagt cctggggaag gggggtttat 1150

 gtcctaactg ctttgtatgc tgttttataa agggat 1186

<210> 3030
<211> 288
<212> PRT
<213> Homo sapien

<400> 3030
 Met Ser Leu Ser Ser Leu Leu Lys Val Val Thr Ala Ser Leu Trp
   1               5                  10                  15

 Leu Gly Pro Gly Ile Ala Gln Lys Ile Thr Gln Thr Gln Pro Gly
                  20                  25                  30

 Met Phe Val Gln Glu Lys Glu Ala Val Thr Leu Asp Cys Thr Tyr
                  35                  40                  45

 Asp Thr Ser Asp Pro Ser Tyr Gly Leu Phe Trp Tyr Lys Gln Pro
                  50                  55                  60

 Ser Ser Gly Glu Met Ile Phe Leu Ile Tyr Gln Gly Ser Tyr Asp
                  65                  70                  75

 Gln Gln Asn Ala Thr Glu Gly Arg Tyr Ser Leu Asn Phe Gln Lys
                  80                  85                  90

 Ala Arg Lys Ser Ala Asn Leu Val Ile Ser Ala Ser Gln Leu Gly
                  95                 100                 105

 Asp Ser Ala Met Tyr Phe Cys Ala Met Arg Ala Val Tyr Thr Asp
                 110                 115                 120

 Lys Leu Ile Phe Gly Lys Gly Thr Arg Val Thr Val Glu Pro Arg
                 125                 130                 135

 Ser Gln Pro His Thr Lys Pro Ser Val Phe Val Met Lys Asn Gly
                 140                 145                 150

 Thr Asn Val Ala Cys Leu Val Lys Glu Phe Tyr Pro Lys Asp Ile
                 155                 160                 165

 Arg Ile Asn Leu Val Ser Ser Lys Lys Ile Thr Glu Phe Asp Pro
                 170                 175                 180

 Ala Ile Val Ile Ser Pro Ser Gly Lys Tyr Asn Ala Val Lys Leu
                 185                 190                 195

 Gly Lys Tyr Glu Asp Ser Asn Ser Val Thr Cys Ser Val Gln His
                 200                 205                 210

 Asp Asn Lys Thr Val His Ser Thr Asp Phe Glu Val Lys Thr Asp
                 215                 220                 225

 Ser Thr Asp His Val Lys Pro Lys Glu Thr Glu Asn Thr Lys Gln
                 230                 235                 240

 Pro Ser Lys Ser Cys His Lys Pro Lys Ala Ile Val His Thr Glu
                 245                 250                 255

 Lys Val Asn Met Met Ser Leu Thr Val Leu Gly Leu Arg Met Leu
                 260                 265                 270

 Phe Ala Lys Thr Val Ala Val Asn Phe Leu Leu Thr Ala Lys Leu
                 275                 280                 285

 Phe Phe Leu


<210> 3031
<211> 1834
<212> DNA
<213> Homo sapien

<400> 3031
 ggaggcacag ataaagataa gttttactgt cacgctgctt ttaacataac 50

 agagcaacat cacctaggaa aaaagtttgt aggaggattt ttaatccata 100

 tatttgtctt atggctagat aaagatttct ctgaaaaaaa gaagcatgtc 150

 aggaatctct gggtgcccct ttttcctctg gggacttcta gcattgttgg 200

 gcttggcttt ggttatatca ctgatcttca atatttccca ctatgtggaa 250

 aagcaacgac aagataaaat gtacagctac tccagtgacc acaccagggt 300

 tgatgagtat tatattgaag acacaccaat ttatggtaac ttagatgata 350

 tgatttcaga accaatggat gaaaattgct atgaacaaat gaaagcccga 400

 ccagagaaat ctgtaaataa gatgcaggaa gccaccccat ctgcacaggc 450

 aaccaatgaa acacagatgt gctacgcctc acttgatcac agcgttaagg 500

 ggaagcgtag aaagcccagg aaacagaata ctcatttctc agacaaggat 550

 ggagatgagc aactacatgc aatagatgcc agcgtttcta agaccacctt 600

 agtagacagt ttctccccag aaagccaggc agtagaggaa acattcatga 650

 tgatcccatc agactgtttg gattgatccg tgctaagaga gaacctataa 700

 actagctgga ccatgatcta gttcaatgat ttggctccta ttgaagatgg 750

 cttctaagaa aacaagatgc acagaggaca cagaaggact tggcagcagg 800

 gtgatgacct gatcatttgt tgatgggatg gtggcttacc tcttattcac 850

 agcttacact tatgcatgcc aaatgtaagg ccatgaaaat cagtatttca 900

 aataccttaa aaaatgcttt actactaaaa tgtaaaaaat taatgtgctc 950

 acctcggcag cacatatact aaaaattaat aagacccagc ttgaaaattg 1000

 agcctgataa caagattaca aattcacaat acctaatact tagggaagta 1050

 taaaaattta agcatgaatg cgttctggaa cacgttagaa gaaaaataaa 1100

 agccaatgag ttttttttta attctccttt ctcaccaatg ggcaatagcc 1150

 cataattgaa ataaatttct gattgaaagg tataggaaac attaaaatgc 1200

 attactaaga gaagtaatat aattttctta caaagtattt ttcccaaaga 1250

 tagctttact atttcaaaaa ttgtcaaatt aatgcatgct ccttacaaca 1300

 aacaaatatc aaaaagagtt taggaattct actagccaga gatagtcact 1350

 tggagaaact ttctatatat ccttctaaat atttttctgg gcatgcttat 1400

 gtatgtacat cagttgtttc tttttatttt gaaccaaaaa tgtggtttct 1450

 tttgtacaca ttacttaaac tttctttcca gtcaaccata tattgtggat 1500

 ttattttcac tgttatattt aactatatat aaatacgcat atattgtaat 1550

 tttaatgtct gcttagcacc ccactgataa ccaaatcaca gtttatttaa 1600

 ataattttaa tgacttttca aaaacaattt attgatgcaa aaagcaaggt 1650

 tgagatgaca atgtttcttt caataattaa aaaatactgc ttcactgtct 1700

 tctctctgtt tcatcagaaa cacatactat aatacttgtc tctgtcctta 1750

 agtgtgatac acgctatttt tctgattgtt aagactttcc ttattactgg 1800

 ttctaatttg attataatat gccaaggtat ggtc 1834

<210> 3032
<211> 176
<212> PRT
<213> Homo sapien

<400> 3032
 Met Ser Gly Ile Ser Gly Cys Pro Phe Phe Leu Trp Gly Leu Leu
   1               5                  10                  15

 Ala Leu Leu Gly Leu Ala Leu Val Ile Ser Leu Ile Phe Asn Ile
                  20                  25                  30

 Ser His Tyr Val Glu Lys Gln Arg Gln Asp Lys Met Tyr Ser Tyr
                  35                  40                  45

 Ser Ser Asp His Thr Arg Val Asp Glu Tyr Tyr Ile Glu Asp Thr
                  50                  55                  60

 Pro Ile Tyr Gly Asn Leu Asp Asp Met Ile Ser Glu Pro Met Asp
                  65                  70                  75

 Glu Asn Cys Tyr Glu Gln Met Lys Ala Arg Pro Glu Lys Ser Val
                  80                  85                  90

 Asn Lys Met Gln Glu Ala Thr Pro Ser Ala Gln Ala Thr Asn Glu
                  95                 100                 105

 Thr Gln Met Cys Tyr Ala Ser Leu Asp His Ser Val Lys Gly Lys
                 110                 115                 120

 Arg Arg Lys Pro Arg Lys Gln Asn Thr His Phe Ser Asp Lys Asp
                 125                 130                 135

 Gly Asp Glu Gln Leu His Ala Ile Asp Ala Ser Val Ser Lys Thr
                 140                 145                 150

 Thr Leu Val Asp Ser Phe Ser Pro Glu Ser Gln Ala Val Glu Glu
                 155                 160                 165

 Thr Phe Met Met Ile Pro Ser Asp Cys Leu Asp
                 170                 175

<210> 3033
<211> 468
<212> DNA
<213> Homo sapien

<400> 3033
 gccccctccc ctgactatca aagcagcggc cggctgttgg ggtccaccac 50

 gccttccacc tgccccactg cttcttcgct tctctcttgg aaagtccagt 100

 ctctcctcgg cttgcaatgg accccaactg ctcctgcgcc gctggtgtct 150

 cctgcacctg cgctggttcc tgcaagtgca aagagtgcaa atgcacctcc 200

 tgcaagaaga gctgctgctc ctgctgcccc gtgggctgta gcaagtgtgc 250

 ccagggctgt gtttgcaaag gggcgtcaga gaagtgcagc tgctgcgact 300

 gatgccagga caacctttct cccagatgta aacagagaga catgtacaaa 350

 cctggatttt tttttatacc accttgaccc atttgctaca ttccttttcc 400

 tgtgaaatat gtgagtgata attaaacact ttagacccaa aaaaaaaaaa 450

 aaaaaaaaaa aaaaaaaa 468

<210> 3034
<211> 61
<212> PRT
<213> Homo sapien

<400> 3034
 Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Val Ser Cys Thr Cys
   1               5                  10                  15

 Ala Gly Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ser Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Val Cys Lys Gly Ala Ser Glu Lys Cys Ser Cys Cys
                  50                  55                  60

 Asp


<210> 3035
<211> 2175
<212> DNA
<213> Homo sapien

<400> 3035
 agcagctctg taatgcgctt gtggtttcag atgtgggcgg cctgtgtgaa 50

 cctgtcgtgc aaagctcacg tcaccaactg ctgcagttat ctcctgaatc 100

 aggctgaggg tctttgctgt gcacccagag atagttgggt gacaaatcac 150

 ctccaggttg gggatgcctc agacttgtga tgggactggg cagatgcatc 200

 tgggaagtaa ctgctgcaag aacggacaga cactgctgca gagaacttgc 250

 cacggtgttt catgctgtgg ctggtggttc caggctgcac gctccattct 300

 aggaaagggg ccctcagccc agtcccttgc aggctggacc ttggagagtg 350

 aggccctgag gcgagacatg ggcacctggc tcctggcctg catctgcatc 400

 tgcacctgtg tctgcttggg agtctctgtc acaggggaag gacaagggcc 450

 aaggtctaga accttcacct gcctcaccaa caacattctc aggatcgatt 500

 gccactggtc tgccccagag ctgggacagg gctccagccc ctggctcctc 550

 ttcaccaggc tcctggcggc acacataagt gcatcttgcg gggcagtgag 600

 tgcaccgtcg tgctgccacc tgaggcagtg ctcgtgccat ctgacaattt 650

 caccatcact ttccaccact gcatgtctgg gagggagcag gtcagcctgg 700

 tggacccgga gtacctgccc cggagacacg agcaacatca gttctggcca 750

 ctgcatcctg acctggagca tcagtcctgc cttggagcca atgaccacac 800

 ttctcagcta tgagctggcc ttcaagaagc aggaagaggc ctgggagcag 850

 gcccagcaca gggatcacat tgtcggggtg acctggctta tacttgaagc 900

 ctttgagctg gaccctggct ttatccatga ggccaggctg cgtgtccaga 950

 tggccacact ggaggatgat gtggtagagg aggagcgtta tacaggccag 1000

 tggagtgagt ggagccagcc tgtgtgcttc caggctcccc agagacaagg 1050

 ccctctgatc ccaccctggg ggtggccagg caacaccctt gttgctgtgt 1100

 ccatctttct cctgctgact ggcccgacct acctcctgtt caagctgtcg 1150

 cccagacttg gatgggggcc cacggggccg gtgtgctgtt gagccaggac 1200

 tgtgctggca ccccacaggg agccttggag ccctgcgtcc aggaggccac 1250

 tgcactgctc acttgtggcc cagcgcgtcc ttggaaatct gtggccctgg 1300

 aggaggaaca ggagggccct gggaccaggc tcccggggaa cctgagctca 1350

 gaggatgtgc tgccagcagg gtgtacggag tggagggtac agacgcttgc 1400

 ctatctgcca caggaggact gggcccccac gtccctgact aggccggctc 1450

 ccccagactc agagggcagc aggagcagca gcagcagcag cagcagcaac 1500

 aacaacaact actgtgcctt gggctgctat gggggatggc acctctcagc 1550

 cctcccagga aacacacaga gctctgggcc catcccagcc ctggcctgtg 1600

 gcctttcttg tgaccatcag ggcctggaga cccagcaagg agttgcctgg 1650

 gtgctggctg gtcactgcca gaggcctggg ctgcatgagg acctccaggg 1700

 catgttgctc ccttctgtcc tcagcaaggc tcggtcctgg acattctagg 1750

 tccctgactc gccagatgca tcatgtccat tttgggaaaa tggactgaag 1800

 tttctggagc ccttgtctga gactgaacct cctgagaagg ggcccctagc 1850

 agcggtcaga ggtcctgtct ggatggaggc tggaggctcc cccctcaacc 1900

 cctctgctca gtgcctgtgg ggagcagcct ctaccctcag catcctggcc 1950

 acaagttctt ccttccattg tcccttttct ttatccctga cctctctgag 2000

 aagtggggtg tggtctctca gctgttctgc cctcataccc ttaaagggcc 2050

 agcctgggcc cagtggacac aggtaaggca ccatgaccac ctggtgtgac 2100

 ctctctgtgc cttactgagg cacctttcta gagattaaaa ggggcttgat 2150

 ggctgttaaa aaaaaaaaaa aaaaa 2175

<210> 3036
<211> 332
<212> PRT
<213> Homo sapien

<400> 3036
 Met His Leu Gly Ser Asn Cys Cys Lys Asn Gly Gln Thr Leu Leu
   1               5                  10                  15

 Gln Arg Thr Cys His Gly Val Ser Cys Cys Gly Trp Trp Phe Gln
                  20                  25                  30

 Ala Ala Arg Ser Ile Leu Gly Lys Gly Pro Ser Ala Gln Ser Leu
                  35                  40                  45

 Ala Gly Trp Thr Leu Glu Ser Glu Ala Leu Arg Arg Asp Met Gly
                  50                  55                  60

 Thr Trp Leu Leu Ala Cys Ile Cys Ile Cys Thr Cys Val Cys Leu
                  65                  70                  75

 Gly Val Ser Val Thr Gly Glu Gly Gln Gly Pro Arg Ser Arg Thr
                  80                  85                  90

 Phe Thr Cys Leu Thr Asn Asn Ile Leu Arg Ile Asp Cys His Trp
                  95                 100                 105

 Ser Ala Pro Glu Leu Gly Gln Gly Ser Ser Pro Trp Leu Leu Phe
                 110                 115                 120

 Thr Arg Leu Leu Ala Ala His Ile Ser Ala Ser Cys Gly Ala Val
                 125                 130                 135

 Ser Ala Pro Ser Cys Cys His Leu Arg Gln Cys Ser Cys His Leu
                 140                 145                 150

 Thr Ile Ser Pro Ser Leu Ser Thr Thr Ala Cys Leu Gly Gly Ser
                 155                 160                 165

 Arg Ser Ala Trp Trp Thr Arg Ser Thr Cys Pro Gly Asp Thr Ser
                 170                 175                 180

 Asn Ile Ser Ser Gly His Cys Ile Leu Thr Trp Ser Ile Ser Pro
                 185                 190                 195

 Ala Leu Glu Pro Met Thr Thr Leu Leu Ser Tyr Glu Leu Ala Phe
                 200                 205                 210

 Lys Lys Gln Glu Glu Ala Trp Glu Gln Ala Gln His Arg Asp His
                 215                 220                 225

 Ile Val Gly Val Thr Trp Leu Ile Leu Glu Ala Phe Glu Leu Asp
                 230                 235                 240

 Pro Gly Phe Ile His Glu Ala Arg Leu Arg Val Gln Met Ala Thr
                 245                 250                 255

 Leu Glu Asp Asp Val Val Glu Glu Glu Arg Tyr Thr Gly Gln Trp
                 260                 265                 270

 Ser Glu Trp Ser Gln Pro Val Cys Phe Gln Ala Pro Gln Arg Gln
                 275                 280                 285

 Gly Pro Leu Ile Pro Pro Trp Gly Trp Pro Gly Asn Thr Leu Val
                 290                 295                 300

 Ala Val Ser Ile Phe Leu Leu Leu Thr Gly Pro Thr Tyr Leu Leu
                 305                 310                 315

 Phe Lys Leu Ser Pro Arg Leu Gly Trp Gly Pro Thr Gly Pro Val
                 320                 325                 330

 Cys Cys


<210> 3037
<211> 328
<212> DNA
<213> Homo sapien

<400> 3037
 cagtctgccc tgactcagcc tcgctcagtg tccggatctc ctggacagtc 50

 agtcaccatc tcctgcaccg gaaccagcag tgatgttggt ggttataact 100

 atgtctcctg gtaccaacag cacccaggca aagcccccac actcatgatt 150

 tatgatgtca ttaagcggcc ctcaggggtc cctgatcgct tctctggctc 200

 caaatctggc aacacggcct ccctgaccat ctctgggctc caggctgagg 250

 atgaggctga ttattattgc agctcaaatg caggcagttt ttatgtcttc 300

 ggaactggga ccaaggtcac cgtcctag 328

<210> 3038
<211> 2314
<212> DNA
<213> Homo sapien

<400> 3038
 cgcgcgcaca gagcgagctc ttgcagcctc cccgcccctc ccgcaacgct 50

 cgaccccagg attcccccgg ctcgcctgcc cgccatggcc gacaaggaag 100

 cagccttcga cgacgcagtg gaagaacgag tgatcaacga ggaatacaaa 150

 atatggaaaa agaacacccc ttttctttat gatttggtga tgacccatgc 200

 tctggagtgg cccagcctaa ctgcccagtg gcttccagat gtaaccagac 250

 cagaagggaa agatttcagc attcatcgac ttgtcctggg gacacacaca 300

 tcggatgaac aaaaccatct tgttatagcc agtgtgcagc tccctaatga 350

 tgatgctcag tttgatgcgt cacactacga cagtgagaaa ggagaatttg 400

 gaggttttgg ttcagttagt ggaaaaattg aaatagaaat caagatcaac 450

 catgaaggag aagtaaacag ggcccgttat atgccccaga acccttgtat 500

 catcgcaaca aagactcctt ccagtgatgt tcttgtcttt gactatacaa 550

 aacatccttc taaaccagat ccttctggag agtgcaaccc agacttgcgt 600

 ctccgtggac atcagaagga aggctatggg ctttcttgga acccaaatct 650

 cagtgggcac ttacttagtg cttcagatga ccataccatc tgcctgtggg 700

 acatcagtgc cgttccaaag gagggaaaag tggtagatgc gaagaccatc 750

 tttacagggc atacggcagt agtagaagat gtttcctggc atctactcca 800

 tgagtctctg tttgggtcag ttgctgatga tcagaaactt atgatttggg 850

 atactcgttc aaacaatact tccaaaccaa gccactcagt tgatgctcac 900

 actgctgaag tgaactgcct ttctttcaat ccttatagtg agttcattct 950

 tgccacagga tcagctgaca agactgttgc cttgtgggat ctgagaaatc 1000

 tgaaacttaa gttgcattcc tttgagtcac ataaggatga aatattccag 1050

 gttcagtggt cacctcacaa tgagactatt ttagcttcca gtggtactga 1100

 tcgcagactg aatgtctggg atttaagtaa aattggagag gaacaatccc 1150

 cagaagatgc agaagacggg ccaccagagt tgttgtttat tcatggtggt 1200

 catactgcca agatatctga tttctcctgg aatcccaatg aaccttgggt 1250

 gatttgttct gtatcagaag acaatatcat gcaagtgtgg caaatggcag 1300

 agaacattta taatgatgaa gaccctgaag gaagcgtgga tccagaagga 1350

 caagggtcct agatatgtct ttacttgttg tgattttaga ctcccctttt 1400

 ttcttctcaa ccctgagagt gatttaacac tggttttgag acagacttta 1450

 ttcagctatc cctctatata ataggtacca ccgataatgc tattagccca 1500

 aaccgtgggt ttttctaaat attaataggg gggcttgatt caacaaagcc 1550

 acagacttaa cgttgaaatt ttcttcagga attttctagt aacccaggtc 1600

 taaagtagct acagaaaggg gaatattatg tgtgattatt tttcttctta 1650

 tgctatatcc ccaagttttt cagactcatt taagtaaagg ctagagtgag 1700

 taaggaatag agccaaatga ggtaggtgtc tgagccatga agtataaata 1750

 ctgaaagatg tcacttttat tcaggaaata gggggagttc aagtcgtata 1800

 gattcctact cgaaaatctt gacacctgac tttccaggat gcacattttc 1850

 atacgtagac cagtttcctc ttggtttctt cagttaagtc aaaacaacac 1900

 gttcctcttt ccccatatat tcatatattt ttgctcgtta gtgtatttct 1950

 tgagctgttt tcatgttgtt tatttcctgt ctgtgaaatg gtgttttttt 2000

 ttttgttgtt ggtttttttt tttttttttt aacttgggac caccaagttg 2050

 taaagatgta tgtttttacc tgacagttat accacaggta gactgtcaag 2100

 ttgagaagag tgaatcaata acttgtattt gttttaaaaa ttaaattaat 2150

 ccttgataag agttgctttt tttttttagg agttagtcct tgaccactag 2200

 tttgatgcca tctccatttt gggtgacctg tttcaccagc aggcctgtta 2250

 ctctccatga ctaactgtgt aagtgcttaa aatggaataa attgcttttc 2300

 tacataaaaa aaaa 2314

<210> 3039
<211> 425
<212> PRT
<213> Homo sapien

<400> 3039
 Met Ala Asp Lys Glu Ala Ala Phe Asp Asp Ala Val Glu Glu Arg
   1               5                  10                  15

 Val Ile Asn Glu Glu Tyr Lys Ile Trp Lys Lys Asn Thr Pro Phe
                  20                  25                  30

 Leu Tyr Asp Leu Val Met Thr His Ala Leu Glu Trp Pro Ser Leu
                  35                  40                  45

 Thr Ala Gln Trp Leu Pro Asp Val Thr Arg Pro Glu Gly Lys Asp
                  50                  55                  60

 Phe Ser Ile His Arg Leu Val Leu Gly Thr His Thr Ser Asp Glu
                  65                  70                  75

 Gln Asn His Leu Val Ile Ala Ser Val Gln Leu Pro Asn Asp Asp
                  80                  85                  90

 Ala Gln Phe Asp Ala Ser His Tyr Asp Ser Glu Lys Gly Glu Phe
                  95                 100                 105

 Gly Gly Phe Gly Ser Val Ser Gly Lys Ile Glu Ile Glu Ile Lys
                 110                 115                 120

 Ile Asn His Glu Gly Glu Val Asn Arg Ala Arg Tyr Met Pro Gln
                 125                 130                 135

 Asn Pro Cys Ile Ile Ala Thr Lys Thr Pro Ser Ser Asp Val Leu
                 140                 145                 150

 Val Phe Asp Tyr Thr Lys His Pro Ser Lys Pro Asp Pro Ser Gly
                 155                 160                 165

 Glu Cys Asn Pro Asp Leu Arg Leu Arg Gly His Gln Lys Glu Gly
                 170                 175                 180

 Tyr Gly Leu Ser Trp Asn Pro Asn Leu Ser Gly His Leu Leu Ser
                 185                 190                 195

 Ala Ser Asp Asp His Thr Ile Cys Leu Trp Asp Ile Ser Ala Val
                 200                 205                 210

 Pro Lys Glu Gly Lys Val Val Asp Ala Lys Thr Ile Phe Thr Gly
                 215                 220                 225

 His Thr Ala Val Val Glu Asp Val Ser Trp His Leu Leu His Glu
                 230                 235                 240

 Ser Leu Phe Gly Ser Val Ala Asp Asp Gln Lys Leu Met Ile Trp
                 245                 250                 255

 Asp Thr Arg Ser Asn Asn Thr Ser Lys Pro Ser His Ser Val Asp
                 260                 265                 270

 Ala His Thr Ala Glu Val Asn Cys Leu Ser Phe Asn Pro Tyr Ser
                 275                 280                 285

 Glu Phe Ile Leu Ala Thr Gly Ser Ala Asp Lys Thr Val Ala Leu
                 290                 295                 300

 Trp Asp Leu Arg Asn Leu Lys Leu Lys Leu His Ser Phe Glu Ser
                 305                 310                 315

 His Lys Asp Glu Ile Phe Gln Val Gln Trp Ser Pro His Asn Glu
                 320                 325                 330

 Thr Ile Leu Ala Ser Ser Gly Thr Asp Arg Arg Leu Asn Val Trp
                 335                 340                 345

 Asp Leu Ser Lys Ile Gly Glu Glu Gln Ser Pro Glu Asp Ala Glu
                 350                 355                 360

 Asp Gly Pro Pro Glu Leu Leu Phe Ile His Gly Gly His Thr Ala
                 365                 370                 375

 Lys Ile Ser Asp Phe Ser Trp Asn Pro Asn Glu Pro Trp Val Ile
                 380                 385                 390

 Cys Ser Val Ser Glu Asp Asn Ile Met Gln Val Trp Gln Met Ala
                 395                 400                 405

 Glu Asn Ile Tyr Asn Asp Glu Asp Pro Glu Gly Ser Val Asp Pro
                 410                 415                 420

 Glu Gly Gln Gly Ser
                 425

<210> 3040
<211> 370
<212> DNA
<213> Homo sapien

<400> 3040
 taacatctgc agtccctcag ctggaagctg agctcttaat gcccctgcct 50

 cccctctgcc ctgggcctgc tctcaactgc cacaagctgg cgcagaagaa 100

 agggcctgag gagatgcggg agctcctctg caggtcctcc caggcaccaa 150

 ccccttctgg gaggaaggct tgggagtccc ctaagacaca tcttcagtca 200

 cttctctctg cctgtgactc aggaagacca gctcctccta ctgtcttctg 250

 tgctagggat cacttccttg ttgagtgggg ccggagtttt aagaggatct 300

 tctgctcctc ctcatctggt ccctttcctt ccaaggcccc cgagaggaag 350

 gcatgcggtg ggccctactg 370

<210> 3041
<211> 122
<212> PRT
<213> Homo sapien

<400> 3041
 Thr Ser Ala Val Pro Gln Leu Glu Ala Glu Leu Leu Met Pro Leu
   1               5                  10                  15

 Pro Pro Leu Cys Pro Gly Pro Ala Leu Asn Cys His Lys Leu Ala
                  20                  25                  30

 Gln Lys Lys Gly Pro Glu Glu Met Arg Glu Leu Leu Cys Arg Ser
                  35                  40                  45

 Ser Gln Ala Pro Thr Pro Ser Gly Arg Lys Ala Trp Glu Ser Pro
                  50                  55                  60

 Lys Thr His Leu Gln Ser Leu Leu Ser Ala Cys Asp Ser Gly Arg
                  65                  70                  75

 Pro Ala Pro Pro Thr Val Phe Cys Ala Arg Asp His Phe Leu Val
                  80                  85                  90

 Glu Trp Gly Arg Ser Phe Lys Arg Ile Phe Cys Ser Ser Ser Ser
                  95                 100                 105

 Gly Pro Phe Pro Ser Lys Ala Pro Glu Arg Lys Ala Cys Gly Gly
                 110                 115                 120

 Pro Tyr


<210> 3042
<211> 330
<212> DNA
<213> Homo sapien

<400> 3042
 atgacatcca ttcgagctgt atttatattc ctgtggctgc agctggactt 50

 ggtgaatgga gagaatgtgg agcagcatcc ttcaaccctg agtgtccagg 100

 agggagacag cgctgttatc aagtgtactt attcagacag tgcctcaaac 150

 tacttccctt ggtataagca agaacttgga aaaggacctc agcttattat 200

 agacattcgt tcaaatgtgg gcgaaaagaa agaccaacga attgctgtta 250

 cattgaacaa gacagccaaa catttctccc tgcacatcac agagacccaa 300

 cctgaagact cggctgtcta cttctgtgca 330

<210> 3043
<211> 109
<212> PRT
<213> Homo sapien

<400> 3043
 Met Thr Ser Ile Arg Ala Val Phe Ile Phe Leu Trp Leu Gln Leu
   1               5                  10                  15

 Asp Leu Val Asn Gly Glu Asn Val Glu Gln His Pro Ser Thr Leu
                  20                  25                  30

 Ser Val Gln Glu Gly Asp Ser Ala Val Ile Lys Cys Thr Tyr Ser
                  35                  40                  45

 Asp Ser Ala Ser Asn Tyr Phe Pro Trp Tyr Lys Gln Glu Leu Gly
                  50                  55                  60

 Lys Gly Pro Gln Leu Ile Ile Asp Ile Arg Ser Asn Val Gly Glu
                  65                  70                  75

 Lys Lys Asp Gln Arg Ile Ala Val Thr Leu Asn Lys Thr Ala Lys
                  80                  85                  90

 His Phe Ser Leu His Ile Thr Glu Thr Gln Pro Glu Asp Ser Ala
                  95                 100                 105

 Val Tyr Phe Cys


<210> 3044
<211> 3075
<212> DNA
<213> Homo sapien

<400> 3044
 acttccgccc cggaaagcga ggccgccacc atcttttggg tccgggagga 50

 ttgagtcatc gggctccaat gcgtggggat gtttaccgcc gtttatccgg 100

 gatagagact ccatcgtgct gacagcatcc ttttattcac cgcctccgaa 150

 tttgcaaaga ggaggaagga gggacttctt ggcttctccc agcatagccc 200

 cagttatgcc atctcagaac tatgaccttc cccagaagaa gcaggagaaa 250

 atgaccaagt ttcaggaggc tgtgacattc aaggatgtgg ctgtggtctt 300

 ctccagggag gaactgcgac tgctcgatct tacccagagg aagctgtacc 350

 gagatgtcat ggtggagaac ttcaagaacc tggttgcagt ggggcatctt 400

 cccttccaac cagatatggt atcccaattg gaagcagaag aaaagctttg 450

 gatgatggaa acagaaaccc aaagaagcag caagcatcaa aataagatgg 500

 aaacactcca aaaatttgca ttaaaatacc tttcaaatca agagctgtcc 550

 tgctggcaaa tctggaaaca ggttgcaagt gaattaacca ggtgtcttca 600

 ggggaagagt tcccagttat tacaaggtga ctctattcag gtttctgaaa 650

 atgagaacaa tataatgaac cctaaaggag atagctctat ttatattgaa 700

 aatcaagagt ttccattttg gagaacccag cattcttgcg ggaatacata 750

 tctgagtgag tcacagattc agagtagagg taagcaaatt gatgtgaaaa 800

 ataacctgca aatacatgaa gacttcatga agaaatcacc atttcatgag 850

 catattaaaa ctgacacaga accaaaaccc tgcaaaggta atgaatatgg 900

 caaaatcatt agtgatggct ccaaccagaa attaccctta ggagagaaac 950

 cccatccatg tggtgagtgt ggaaggggct tcagttatag cccaaggctt 1000

 ccccttcatc cgaatgttca cacaggagaa aaatgcttca gtcaaagctc 1050

 acatctgcga actcatcaga gaattcaccc aggagagaaa ctcaatagat 1100

 gtcatgaatc tggtgattgc ttcaataaga gctcttttca ttcttatcaa 1150

 tctaatcata caggagagaa gtcttataga tgcgacagtt gcggcaaggg 1200

 attcagtagc agcacgggtc ttatcattca ttacagaact catactggag 1250

 agaaacccta taaatgcgag gaatgtggta aatgctttag tcaaagttca 1300

 aattttcagt gccatcagag agtccacact gaagaaaaac catacaaatg 1350

 cgaagagtgt ggtaagggct tcggttggag tgttaatctc cgtgttcacc 1400

 agagggtcca caggggtgag aagccctata aatgtgagga atgtggtaag 1450

 ggcttcactc aggctgcaca ttttcacatc catcagagag tccacactgg 1500

 agagaaaccc tacaagtgtg atgtgtgtgg taagggcttc agccacaatt 1550

 caccattaat atgccatcgg agagtccaca caggagagaa gccatacaag 1600

 tgtgaggcgt gtgggaaagg ctttacccgt aatacagatc tgcatattca 1650

 tttcagagtt cacacgggag agaaacccta taaatgtaag gagtgtggta 1700

 agggcttcag tcaggcttca aatcttcaag tccatcagaa tgtccacact 1750

 ggggagaaac gattcaagtg tgaaacgtgt gggaagggct tcagtcagtc 1800

 ctcaaagctt caaacccatc agcgagtcca cactggagag aaaccatata 1850

 gatgtgatgt gtgtggtaag gacttcagtt atagttcaaa tcttaaacta 1900

 caccaagtaa ttcacactgg agaaaaacca tataaatgtg aggaatgtgg 1950

 gaagggcttc agttggagat caaatcttca tgcacatcaa agagttcact 2000

 caggagaaaa accctataaa tgtgagcagt gtgataagag cttcagtcag 2050

 gccatagatt ttcgggtaca tcagagagtc catactggag agaagccata 2100

 caaatgtggt gtctgtggta agggcttcag tcagtcctct ggtcttcaat 2150

 cccatcagag agtccacacg ggggaaaagc catacaaatg tgatgtgtgt 2200

 ggaaagggct ttagatacag ttcgcagttt atataccatc agagaggcca 2250

 cactggagaa aaaccttaca aatgtgaaga gtgtgggaaa ggctttggta 2300

 ggagcttgaa tcttcgccat catcagaggg tccacacggg agagaaaccc 2350

 catatatgtg aggagtgtgg taaggccttc agtctcccct caaatcttcg 2400

 agtccacctg ggtgttcaca ccagggaaaa actctttaaa tgtgaagagt 2450

 gtggtaaagg cttcagtcag agtgcacgtc ttgaagccca tcagagagtc 2500

 cacactggag aaaaaccata caaatgtgac atatgtgata aggacttccg 2550

 tcaccgttca cgtcttacat atcatcagaa agtccatact ggtaaaaagc 2600

 tttagaaatg agaaatgtgt taccaacttt tgtctgaatg cacatcttca 2650

 agtttttggc tagtccatgc tggtggtaaa ccctgtaaaa ctactgagag 2700

 tggaaggggg tttgttcaca cttggaatct ttctaacaaa tccatcaaga 2750

 tgataacaca gaaccatgaa caggaataga actcgtattt aggggagaaa 2800

 tagggctggt ggctctcttg gtaagatcta gttaatataa atgatcacct 2850

 ttcattgtga atatatgcct gaagataatg tgtggaagga tatttgccat 2900

 atgctaactg gttttttggc cagggagagt tttgggttat tatccctttt 2950

 ctttaatttt cattttatac ttacagtgat cattattttc ataaaagctg 3000

 taaagctatg aaaaatgaat aaaattacta aaaattttct gtaaaaaaaa 3050

 aaaaaaaaga aaaaaaaaaa aaaaa 3075

<210> 3045
<211> 799
<212> PRT
<213> Homo sapien

<400> 3045
 Met Pro Ser Gln Asn Tyr Asp Leu Pro Gln Lys Lys Gln Glu Lys
   1               5                  10                  15

 Met Thr Lys Phe Gln Glu Ala Val Thr Phe Lys Asp Val Ala Val
                  20                  25                  30

 Val Phe Ser Arg Glu Glu Leu Arg Leu Leu Asp Leu Thr Gln Arg
                  35                  40                  45

 Lys Leu Tyr Arg Asp Val Met Val Glu Asn Phe Lys Asn Leu Val
                  50                  55                  60

 Ala Val Gly His Leu Pro Phe Gln Pro Asp Met Val Ser Gln Leu
                  65                  70                  75

 Glu Ala Glu Glu Lys Leu Trp Met Met Glu Thr Glu Thr Gln Arg
                  80                  85                  90

 Ser Ser Lys His Gln Asn Lys Met Glu Thr Leu Gln Lys Phe Ala
                  95                 100                 105

 Leu Lys Tyr Leu Ser Asn Gln Glu Leu Ser Cys Trp Gln Ile Trp
                 110                 115                 120

 Lys Gln Val Ala Ser Glu Leu Thr Arg Cys Leu Gln Gly Lys Ser
                 125                 130                 135

 Ser Gln Leu Leu Gln Gly Asp Ser Ile Gln Val Ser Glu Asn Glu
                 140                 145                 150

 Asn Asn Ile Met Asn Pro Lys Gly Asp Ser Ser Ile Tyr Ile Glu
                 155                 160                 165

 Asn Gln Glu Phe Pro Phe Trp Arg Thr Gln His Ser Cys Gly Asn
                 170                 175                 180

 Thr Tyr Leu Ser Glu Ser Gln Ile Gln Ser Arg Gly Lys Gln Ile
                 185                 190                 195

 Asp Val Lys Asn Asn Leu Gln Ile His Glu Asp Phe Met Lys Lys
                 200                 205                 210

 Ser Pro Phe His Glu His Ile Lys Thr Asp Thr Glu Pro Lys Pro
                 215                 220                 225

 Cys Lys Gly Asn Glu Tyr Gly Lys Ile Ile Ser Asp Gly Ser Asn
                 230                 235                 240

 Gln Lys Leu Pro Leu Gly Glu Lys Pro His Pro Cys Gly Glu Cys
                 245                 250                 255

 Gly Arg Gly Phe Ser Tyr Ser Pro Arg Leu Pro Leu His Pro Asn
                 260                 265                 270

 Val His Thr Gly Glu Lys Cys Phe Ser Gln Ser Ser His Leu Arg
                 275                 280                 285

 Thr His Gln Arg Ile His Pro Gly Glu Lys Leu Asn Arg Cys His
                 290                 295                 300

 Glu Ser Gly Asp Cys Phe Asn Lys Ser Ser Phe His Ser Tyr Gln
                 305                 310                 315

 Ser Asn His Thr Gly Glu Lys Ser Tyr Arg Cys Asp Ser Cys Gly
                 320                 325                 330

 Lys Gly Phe Ser Ser Ser Thr Gly Leu Ile Ile His Tyr Arg Thr
                 335                 340                 345

 His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Cys
                 350                 355                 360

 Phe Ser Gln Ser Ser Asn Phe Gln Cys His Gln Arg Val His Thr
                 365                 370                 375

 Glu Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Gly Phe Gly
                 380                 385                 390

 Trp Ser Val Asn Leu Arg Val His Gln Arg Val His Arg Gly Glu
                 395                 400                 405

 Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Gly Phe Thr Gln Ala
                 410                 415                 420

 Ala His Phe His Ile His Gln Arg Val His Thr Gly Glu Lys Pro
                 425                 430                 435

 Tyr Lys Cys Asp Val Cys Gly Lys Gly Phe Ser His Asn Ser Pro
                 440                 445                 450

 Leu Ile Cys His Arg Arg Val His Thr Gly Glu Lys Pro Tyr Lys
                 455                 460                 465

 Cys Glu Ala Cys Gly Lys Gly Phe Thr Arg Asn Thr Asp Leu His
                 470                 475                 480

 Ile His Phe Arg Val His Thr Gly Glu Lys Pro Tyr Lys Cys Lys
                 485                 490                 495

 Glu Cys Gly Lys Gly Phe Ser Gln Ala Ser Asn Leu Gln Val His
                 500                 505                 510

 Gln Asn Val His Thr Gly Glu Lys Arg Phe Lys Cys Glu Thr Cys
                 515                 520                 525

 Gly Lys Gly Phe Ser Gln Ser Ser Lys Leu Gln Thr His Gln Arg
                 530                 535                 540

 Val His Thr Gly Glu Lys Pro Tyr Arg Cys Asp Val Cys Gly Lys
                 545                 550                 555

 Asp Phe Ser Tyr Ser Ser Asn Leu Lys Leu His Gln Val Ile His
                 560                 565                 570

 Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Gly Phe
                 575                 580                 585

 Ser Trp Arg Ser Asn Leu His Ala His Gln Arg Val His Ser Gly
                 590                 595                 600

 Glu Lys Pro Tyr Lys Cys Glu Gln Cys Asp Lys Ser Phe Ser Gln
                 605                 610                 615

 Ala Ile Asp Phe Arg Val His Gln Arg Val His Thr Gly Glu Lys
                 620                 625                 630

 Pro Tyr Lys Cys Gly Val Cys Gly Lys Gly Phe Ser Gln Ser Ser
                 635                 640                 645

 Gly Leu Gln Ser His Gln Arg Val His Thr Gly Glu Lys Pro Tyr
                 650                 655                 660

 Lys Cys Asp Val Cys Gly Lys Gly Phe Arg Tyr Ser Ser Gln Phe
                 665                 670                 675

 Ile Tyr His Gln Arg Gly His Thr Gly Glu Lys Pro Tyr Lys Cys
                 680                 685                 690

 Glu Glu Cys Gly Lys Gly Phe Gly Arg Ser Leu Asn Leu Arg His
                 695                 700                 705

 His Gln Arg Val His Thr Gly Glu Lys Pro His Ile Cys Glu Glu
                 710                 715                 720

 Cys Gly Lys Ala Phe Ser Leu Pro Ser Asn Leu Arg Val His Leu
                 725                 730                 735

 Gly Val His Thr Arg Glu Lys Leu Phe Lys Cys Glu Glu Cys Gly
                 740                 745                 750

 Lys Gly Phe Ser Gln Ser Ala Arg Leu Glu Ala His Gln Arg Val
                 755                 760                 765

 His Thr Gly Glu Lys Pro Tyr Lys Cys Asp Ile Cys Asp Lys Asp
                 770                 775                 780

 Phe Arg His Arg Ser Arg Leu Thr Tyr His Gln Lys Val His Thr
                 785                 790                 795

 Gly Lys Lys Leu


<210> 3046
<211> 1581
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1396-1413
<223> Unknown base

<400> 3046
 cacagatcct aatttagcct catggatcca gaggcaaaaa aagtttaatc 50

 cctcttttac attatataga ctttcaaaat tcaaagacgg ctgtcatgcg 100

 ttcctggagc cctcactctt gctaattagg cttctgactt cagacaggtc 150

 agaagctctg tccagcaaaa tttttaaatc tttaatataa ggagcatgaa 200

 ccagatgaca tttaagatcc ttccctctct gacattctat aaacttcagt 250

 ttgagtctct gaaaaaaatg gaactttttt gctttttccc tttcttttca 300

 ccatctatat caaatataga tgattctctt gagtagtaaa agagtacaag 350

 catattcaat gctatttctt aggaaccgtt aattaatctt tcaacaatca 400

 attcaatcat gattacaaca gctttgatga gcactagtgc tacagcaact 450

 gagacagcaa ccaagaggca agaaacctgg gattggtttt catggttgtt 500

 tctaccatca gagtcaaaga atcatcttca cacaacaaca caaatggctg 550

 gtaatgagtt attattatct catagcgtat gttttcttga cagccttgaa 600

 taattttgat tgacctctgg gatgttatta aagcctaacg ttccttctat 650

 tctcacaaat tttcgttatg acttcagaag gatcattaac tctggtatct 700

 gtttgtttgc ttgtatggca ccaataagca gatttcttct ttctaatcta 750

 tggattagta tagaccagga gaaggctaat acagagacta tgaaacggga 800

 ataagttttt ttaacgatat ggcaaaattg tgactctgaa agatcattca 850

 tgtatattct aaaattacca cagtcataaa aagtcttgga ctttcatgag 900

 gaaatagcat agctagatat gaaaaaatat agaaaatctt catcaatgga 950

 actattcttg gggtagacac taatcatatg aaaagacaaa tgctcattcc 1000

 ctaagatagc ctgaatctca tttaaaatgt agaaaacccc tttttagtaa 1050

 agagacatct tctacagtaa ccactgagaa gaagtggaag tttttcatct 1100

 ccttttttta ttcaaaaaga aaaagaattt ctcaatttct gaaccacagt 1150

 tcactttagt taaccccttt gattgcctaa taatgccaaa aatgatttct 1200

 ctgttaattg gcttcacatt tttgctctat gctgaagtag tattgggaac 1250

 tgcagtgtag cttccatctc tgtttggagg tacactgatc tgatctgata 1300

 ctagagaaga taaaaaatga attagcaaat tgtgaacaca atgaaatgac 1350

 tgacgtaggt gtagattcca acatttttct gaaggtgtct tgaccnnnnn 1400

 nnnnnnnnnn nnnggcacgt gtgaaacctt tccattctgt tcttgatggc 1450

 ttggctttaa tggcatatgg ttaatgagtt aataataaac atatctgaaa 1500

 gtgtggggga gttttcatta gcctttaaaa acttatatgg tgagattatg 1550

 tccacactta ttctttcagc tttcttaaag a 1581

<210> 3047
<211> 62
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1396-1413
<223> Unknown amino acid

<400> 3047
 Thr Asp Pro Asn Leu Ala Ser Trp Ile Gln Arg Gln Lys Lys Phe
   1               5                  10                  15

 Asn Pro Ser Phe Thr Leu Tyr Arg Leu Ser Lys Phe Lys Asp Gly
                  20                  25                  30

 Cys His Ala Phe Leu Glu Pro Ser Leu Leu Leu Ile Arg Leu Leu
                  35                  40                  45

 Thr Ser Asp Arg Ser Glu Ala Leu Ser Ser Lys Ile Phe Lys Ser
                  50                  55                  60

 Leu Ile


<210> 3048
<211> 712
<212> DNA
<213> Homo sapien

<400> 3048
 atcaaattta gctctcactt atcagtgaga acaactttca tcccacatct 50

 aatttgtctt tcttcactct ggtgtggaaa ttttgataga gattccaata 100

 tcacttaaac gtttcccaga atatttagat agaataattt agtttcttct 150

 gaaaagttta ttttaggcta gtgccacatg gttgtgaata ttagcatggt 200

 agccaaataa tagtttgttt aaatgtatat ttcccaatat aaatataagg 250

 ggcatcataa tttttaaaaa ctataaaatc tagaagaaaa atctatggat 300

 aaaatccata attctatcat ctgaatgcaa tgaacattag catttaggta 350

 tattttcttg caggtttttt aaccatatac ttatagagaa tatgtaattt 400

 gggtctgtgt tttttacata taaatatttt tctatgttaa atagtcttca 450

 taagttaatt ataaagatct gcttaatagt tctgctactg cagttttcat 500

 tattagataa gttggtcatt atagttggac atttaggttt acaatattaa 550

 agcagtggtt tatatcaatt tcagtggttt aaaatatgaa tttctatttt 600

 ggaatgaaag tattaattta atgtagtgaa tctcatattc cagaactgag 650

 atgattgatt tgatgctatt tgtgacagac agaacccata ataaagcctt 700

 tctatgcaag tt 712

<210> 3049
<211> 35
<212> PRT
<213> Homo sapien

<400> 3049
 Ile Lys Phe Ser Ser His Leu Ser Val Arg Thr Thr Phe Ile Pro
   1               5                  10                  15

 His Leu Ile Cys Leu Ser Ser Leu Trp Cys Gly Asn Phe Asp Arg
                  20                  25                  30

 Asp Ser Asn Ile Thr
                  35

<210> 3050
<211> 412
<212> DNA
<213> Homo sapien

<400> 3050
 gttcgatgtg actgcagtat gagattaaag ccacaactat tgtttatttt 50

 ggggactcta ggccaccaag tattagcaca catacttatg ttttctctac 100

 taatctggtc caggtcctca tggaccacag gacaaagctt tcattttcat 150

 tcattcttct attgaaatta taccaaattc agctgaggaa tatggaagta 200

 actttagact taaacaagac aaaagttttt tcactgaaga attgacaagt 250

 atttgctcct taaaacaatg cagattagtg aacgtggatt cctgctgagg 300

 ggagtgcatc ccataatatg gcaataattt tcagtttctc caacgaaaag 350

 atagtgaagg aattaaatct tttgtcctcc catggttaaa aaaaaaaaaa 400

 aagctgtgtt ca 412

<210> 3051
<211> 54
<212> PRT
<213> Homo sapien

<400> 3051
 Val Arg Cys Asp Cys Ser Met Arg Leu Lys Pro Gln Leu Leu Phe
   1               5                  10                  15

 Ile Leu Gly Thr Leu Gly His Gln Val Leu Ala His Ile Leu Met
                  20                  25                  30

 Phe Ser Leu Leu Ile Trp Ser Arg Ser Ser Trp Thr Thr Gly Gln
                  35                  40                  45

 Ser Phe His Phe His Ser Phe Phe Tyr
                  50

<210> 3052
<211> 3483
<212> DNA
<213> Homo sapien

<400> 3052
 aaaatcttgt gggaagagct gaagcaggcg ctcttggctc ggcgcggccc 50

 gctgcaatcc gtggaggaac gcgccgccga gccaccatca tgcctgggca 100

 cttacaggaa ggcttcggct gcgtggtcac caaccgattc gaccagttat 150

 ttgacgacga atcggacccc ttcgaggtgc tgaaggcagc agagaacaag 200

 aaaaaagaag ccggcggggg cggcgttggg ggccctgggg ccaagagcgc 250

 agctcaggcc gcggcccaga ccaactccaa cgcggcaggc aaacagctgc 300

 gcaaggagtc ccagaaagac cgcaagaacc cgctgccccc cagcgttggc 350

 gtggttgaca agaaagagga gacgcagccg cccgtggcgc ttaagaaaga 400

 aggaataaga cgagttggaa gaagacctga tcaacaactt cagggtgaag 450

 ggaaaataat tgatagaaga ccagaaaggc gaccacctcg tgaacgaaga 500

 ttcgaaaagc cacttgaaga aaagggtgaa ggaggcgaat tttcagttga 550

 tagaccgatt attgaccgac ctattcgagg tcgtggtggt cttggaagag 600

 gtcgaggggg ccgtggacgt ggaatgggcc gaggagatgg atttgattct 650

 cgtggcaaac gtgaatttga taggcatagt ggaagtgata gatcttcttt 700

 ttcacattac agtggcctga agcacgagga caaacgtgga ggtagcggat 750

 ctcacaactg gggaactgtc aaagacgaat taacagagtc ccccaaatac 800

 attcagaaac aaatatctta taattacagt gacttggatc aatcaaatgt 850

 gactgaggaa acacctgaag gtgaagaaca tcatccagtg gcagacactg 900

 aaaataagga gaatgaagtt gaagaggtaa aagaggaggg tccaaaagag 950

 atgactttgg atgagtggaa ggctattcaa aataaggacc gggcaaaagt 1000

 agaatttaat atccgaaaac caagtgaagg tgctgatggg cagtggaaga 1050

 agggatttgt tcttcataaa tcaaagagtg aagaggctca tgctgaagat 1100

 tcggttatgg accatcattt ccggaagcca gcaaatgata taacgtctca 1150

 gctggagatc aattttggag accttggccg cccaggacgt ggcggcaggg 1200

 gaggacgagg tggacgtggg cgtggtgggc gcccaaaccg tggcagcagg 1250

 accgacaagt caagtgcttc tgctcctgat gtggatgacc cagaggcatt 1300

 cccagctctg gcttaactgg atgccataag acaaccctgg ttcctttgtg 1350

 aacccttctg ttcaaagctt ttgcatgctt aaggattcca aacgactaag 1400

 aaattaaaaa aaaaaagact gtcattcata ccattcacac ctaaagactg 1450

 aattttatct gttttaaaaa tgaacttctc ccgctacaca gaagtaacaa 1500

 atatggtagt cagttttgta tttagaaatg tattggtagc agggatgttt 1550

 tcataatttt cagagattat gcattcttca tgaatacttt tgtattgctg 1600

 cttgcaaata tgcatttcca aacttgaaat ataggtgtga acagtgtgta 1650

 ccagtttaaa gctttcactt catttgtgtt ttttaattaa ggatttagaa 1700

 gttcccccaa ttacaaactg gttttaaata ttggacatac tggttttaat 1750

 acctgctttg catattcaca catggtcaac tgggacatgt taaactttga 1800

 tttgtcaaat tttatgctgt gtggaatact aactatatgt attttaactt 1850

 agttttaata ttttcatttt tggggaaaaa tcttttttca cttctcatga 1900

 tagctgttat atatatatgc taaatcttta tatacagaaa tatcagtact 1950

 tgaacaaatt caaagcacat ttggtttatt aacccttgct ccttgcatgg 2000

 ctcattaggt tcaaattata actgatttac attttcagct atatttactt 2050

 tttaaatgct tgagtttccc attttaaaat ctaaactaga catcttaatt 2100

 ggtgaaagtt gtttaaacta cttattgttg gtaggcacat cgtgtcaagt 2150

 gaagtagttt tataggtatg ggttttttct cccccttcac cagggtgggt 2200

 ggaataagtt gatttggcca atgtgtaata tttaaactgt tctgtaaaat 2250

 aagtgtctgg ccatttggta tgatttctgt gtgtgaaagg tcccaaaatc 2300

 aaaatggtac atccataatc agccaccatt taacccttcc ttgttctaaa 2350

 acaaaaacca aagggcgctg gttggtaggg tgaggtgggg gagtatttta 2400

 atttttggaa tttgggaagc agacagcttt actttgtaag gttggaacag 2450

 cagcactata catgaaatat aaaccaaaaa cctttactgt ttctaaattt 2500

 cctagattgc tattatttgg ttgtaagttg agtattccac agaaggtggt 2550

 aattatctct tctctcttcc tccattagaa aattaggtaa ataatggatt 2600

 cctataatgg gagcatcacc acttattaaa acacacatag aatgatgaat 2650

 taaaaaagtt ttctaggatt gtcttttatt ctgccacatt tattgataaa 2700

 cagtgaagga atttttaaaa aatttttaag aattgtttgt cacgtcattt 2750

 ttagaaatgt tctacctgta tatggtaatg tccagtttta aaaatattgg 2800

 acatcttcaa tcttaaacat ttctatttag ctgattggtt ctcacatata 2850

 cttctaaaag aaacttttat gttataagag ttactttttg gataagattt 2900

 attaatctca gttacctact attctgacat tttaggaagg aggtaattgt 2950

 ttttaatgat ggataaactt gtgctggtgt tttggatctt atgatgctga 3000

 gcatgttctg cactggtgct aatgtctaat aattttatat ttacacacat 3050

 acgtgctacc cagagattaa tttagtccat atgaactatt gacccattgt 3100

 tcattgagac agcaacatac gcactcctaa atcagtgtgt ttagactttt 3150

 caagtatcta actcatttcc aaacatgtac catgttttat aaacctcttg 3200

 atttccagca acatactata gaaaacacct gctactcaaa acacaacttc 3250

 tcagtgtcat ccattgctgt cgtgagagac aacatagcaa tatctggtat 3300

 gttgcaagct ttcaagatag cctgaactta aaaagttggt gcattagttg 3350

 tatctgatgg atataaattt gcctcctagt tcactttgtg tcaagagcta 3400

 aaactgtgaa cctaactttc tcttattggt gggtaataac tgaaaataaa 3450

 gatttatttt catgctcact tcttaaaagt cat 3483

<210> 3053
<211> 408
<212> PRT
<213> Homo sapien

<400> 3053
 Met Pro Gly His Leu Gln Glu Gly Phe Gly Cys Val Val Thr Asn
   1               5                  10                  15

 Arg Phe Asp Gln Leu Phe Asp Asp Glu Ser Asp Pro Phe Glu Val
                  20                  25                  30

 Leu Lys Ala Ala Glu Asn Lys Lys Lys Glu Ala Gly Gly Gly Gly
                  35                  40                  45

 Val Gly Gly Pro Gly Ala Lys Ser Ala Ala Gln Ala Ala Ala Gln
                  50                  55                  60

 Thr Asn Ser Asn Ala Ala Gly Lys Gln Leu Arg Lys Glu Ser Gln
                  65                  70                  75

 Lys Asp Arg Lys Asn Pro Leu Pro Pro Ser Val Gly Val Val Asp
                  80                  85                  90

 Lys Lys Glu Glu Thr Gln Pro Pro Val Ala Leu Lys Lys Glu Gly
                  95                 100                 105

 Ile Arg Arg Val Gly Arg Arg Pro Asp Gln Gln Leu Gln Gly Glu
                 110                 115                 120

 Gly Lys Ile Ile Asp Arg Arg Pro Glu Arg Arg Pro Pro Arg Glu
                 125                 130                 135

 Arg Arg Phe Glu Lys Pro Leu Glu Glu Lys Gly Glu Gly Gly Glu
                 140                 145                 150

 Phe Ser Val Asp Arg Pro Ile Ile Asp Arg Pro Ile Arg Gly Arg
                 155                 160                 165

 Gly Gly Leu Gly Arg Gly Arg Gly Gly Arg Gly Arg Gly Met Gly
                 170                 175                 180

 Arg Gly Asp Gly Phe Asp Ser Arg Gly Lys Arg Glu Phe Asp Arg
                 185                 190                 195

 His Ser Gly Ser Asp Arg Ser Ser Phe Ser His Tyr Ser Gly Leu
                 200                 205                 210

 Lys His Glu Asp Lys Arg Gly Gly Ser Gly Ser His Asn Trp Gly
                 215                 220                 225

 Thr Val Lys Asp Glu Leu Thr Glu Ser Pro Lys Tyr Ile Gln Lys
                 230                 235                 240

 Gln Ile Ser Tyr Asn Tyr Ser Asp Leu Asp Gln Ser Asn Val Thr
                 245                 250                 255

 Glu Glu Thr Pro Glu Gly Glu Glu His His Pro Val Ala Asp Thr
                 260                 265                 270

 Glu Asn Lys Glu Asn Glu Val Glu Glu Val Lys Glu Glu Gly Pro
                 275                 280                 285

 Lys Glu Met Thr Leu Asp Glu Trp Lys Ala Ile Gln Asn Lys Asp
                 290                 295                 300

 Arg Ala Lys Val Glu Phe Asn Ile Arg Lys Pro Ser Glu Gly Ala
                 305                 310                 315

 Asp Gly Gln Trp Lys Lys Gly Phe Val Leu His Lys Ser Lys Ser
                 320                 325                 330

 Glu Glu Ala His Ala Glu Asp Ser Val Met Asp His His Phe Arg
                 335                 340                 345

 Lys Pro Ala Asn Asp Ile Thr Ser Gln Leu Glu Ile Asn Phe Gly
                 350                 355                 360

 Asp Leu Gly Arg Pro Gly Arg Gly Gly Arg Gly Gly Arg Gly Gly
                 365                 370                 375

 Arg Gly Arg Gly Gly Arg Pro Asn Arg Gly Ser Arg Thr Asp Lys
                 380                 385                 390

 Ser Ser Ala Ser Ala Pro Asp Val Asp Asp Pro Glu Ala Phe Pro
                 395                 400                 405

 Ala Leu Ala


<210> 3054
<211> 2201
<212> DNA
<213> Homo sapien

<400> 3054
 gggggtggga agagctgaag caggcgctct tggctcggcg cggcccgctg 50

 caatccgtgg aggaacgcgc cgccgagcca ccatcatgcc tgggcactta 100

 caggaaggct tcggctgcgt ggtcaccaac cgattcgacc agttatttga 150

 cgacgaatcg gaccccttcg aggtgctgaa ggcagcagag aacaagaaaa 200

 aagaagccgg cgggggcggc gttgggggcc ctggggccaa gagcgcagct 250

 caggccgcgg cccagaccaa ctccaacgcg gcaggcaaac agctgcgcaa 300

 ggagtcccag aaagaccgca agaacccgct gccccccagc gttggcgtgg 350

 ttgacaagaa agaggagacg cagccgcccg tggcgcttaa gaaagaagga 400

 ataagacgag ttggaagaag acctgatcaa caacttcagg gtgaagggaa 450

 aataattgat agaagaccag aaaggcgacc acctcgtgaa cgaagattcg 500

 aaaagccact tgaagaaaag ggtgaaggag gcgaattttc agttgataga 550

 ccgattattg accgacctat tcgaggtcgt ggtggtcttg gaagaggtcg 600

 agggggccgt ggacgtggaa tgggccgagg agatggattt gattctcgtg 650

 gcaaacgtga atttgatagg catagtggaa gtgatagatc tggcctgaag 700

 cacgaggaca aacgtggagg tagcggatct cacaactggg gaactgtcaa 750

 agacgaatta actgacttgg atcaatcaaa tgtgactgag gaaacacctg 800

 aaggtgaaga acatcatcca gtggcagaca ctgaaaataa ggagaatgaa 850

 gttgaagagg taaaagagga gggtccaaaa gagatgactt tggatgagtg 900

 gaaggctatt caaaataagg accgggcaaa agtagaattt aatatccgaa 950

 aaccaaatga aggtgctgat gggcagtgga agaagggatt tgttcttcat 1000

 aaatcaaaga gtgaagaggc tcatgctgaa gattcggtta tggaccatca 1050

 tttccggaag ccagcaaatg atataacgtc tcagctggag atcaattttg 1100

 gagaccttgg ccgcccagga cgtggcggca ggggaggacg aggtggacgt 1150

 gggcgtggtg ggcgcccaaa ccgtggcagc aggaccgaca agtcaagtgc 1200

 ttctgctcct gatgtggatg acccagaggc attcccagct ctggcttaac 1250

 tggatgccat aagacaaccc tggttccttt gtgaaccctt ctgttcaaag 1300

 cttttgcatg cttaaggatt ccaaacgact aagaaattaa aaaaaaaaag 1350

 actgtcattc ataccattca cacctaaaga ctgaatttta tctgttttaa 1400

 aaatgaactt ctcccgctac acagaagtaa caaatatggt agtcagtttt 1450

 gtatttagaa atgtattggt agcagggatg ttttcataat tttcagagat 1500

 tatgcattct tcatgaatac ttttgtattg ctgcttgcaa atatgcattt 1550

 ccaaacttga aatataggtg tgaacagtgt gtaccagttt aaagctttca 1600

 cttcatttgt gttttttaat taaggactta gaagttcccc caattacaaa 1650

 ctggttttaa atattggaca tactggtttt aatacctgct ttgcatattc 1700

 acacatggtc aactgggaca tgttaaactt tgatttgtca aattttatgc 1750

 tgtgtggaat actaactata tgtattttaa cttagtttta atattttcat 1800

 tttgggggaa aaatcttttt tcacttctca tgatagctgt tatatatata 1850

 tgctaaatct ttatatacag aaatatcagt acttgaacaa attcaaagca 1900

 catttggttt attaaccctt gctccttgca tggctcatta ggttcaaatt 1950

 ataactaatt tacattttca gctatattta ctttttaaat gcttgagttt 2000

 cccattttaa aatctaaact agacatctta attggtgaaa gttgtttaaa 2050

 ctacttattg ttggtaggca catcgtgtca agtgaagtag ttttataggt 2100

 atgggttttt tctccccctt caccagggtg ggtggaataa gttgatttgg 2150

 ccaatgtgta atatttaaac tgttctgtaa aataaaaaaa aaaaaaaaaa 2200

 a 2201

<210> 3055
<211> 387
<212> PRT
<213> Homo sapien

<400> 3055
 Met Pro Gly His Leu Gln Glu Gly Phe Gly Cys Val Val Thr Asn
   1               5                  10                  15

 Arg Phe Asp Gln Leu Phe Asp Asp Glu Ser Asp Pro Phe Glu Val
                  20                  25                  30

 Leu Lys Ala Ala Glu Asn Lys Lys Lys Glu Ala Gly Gly Gly Gly
                  35                  40                  45

 Val Gly Gly Pro Gly Ala Lys Ser Ala Ala Gln Ala Ala Ala Gln
                  50                  55                  60

 Thr Asn Ser Asn Ala Ala Gly Lys Gln Leu Arg Lys Glu Ser Gln
                  65                  70                  75

 Lys Asp Arg Lys Asn Pro Leu Pro Pro Ser Val Gly Val Val Asp
                  80                  85                  90

 Lys Lys Glu Glu Thr Gln Pro Pro Val Ala Leu Lys Lys Glu Gly
                  95                 100                 105

 Ile Arg Arg Val Gly Arg Arg Pro Asp Gln Gln Leu Gln Gly Glu
                 110                 115                 120

 Gly Lys Ile Ile Asp Arg Arg Pro Glu Arg Arg Pro Pro Arg Glu
                 125                 130                 135

 Arg Arg Phe Glu Lys Pro Leu Glu Glu Lys Gly Glu Gly Gly Glu
                 140                 145                 150

 Phe Ser Val Asp Arg Pro Ile Ile Asp Arg Pro Ile Arg Gly Arg
                 155                 160                 165

 Gly Gly Leu Gly Arg Gly Arg Gly Gly Arg Gly Arg Gly Met Gly
                 170                 175                 180

 Arg Gly Asp Gly Phe Asp Ser Arg Gly Lys Arg Glu Phe Asp Arg
                 185                 190                 195

 His Ser Gly Ser Asp Arg Ser Gly Leu Lys His Glu Asp Lys Arg
                 200                 205                 210

 Gly Gly Ser Gly Ser His Asn Trp Gly Thr Val Lys Asp Glu Leu
                 215                 220                 225

 Thr Asp Leu Asp Gln Ser Asn Val Thr Glu Glu Thr Pro Glu Gly
                 230                 235                 240

 Glu Glu His His Pro Val Ala Asp Thr Glu Asn Lys Glu Asn Glu
                 245                 250                 255

 Val Glu Glu Val Lys Glu Glu Gly Pro Lys Glu Met Thr Leu Asp
                 260                 265                 270

 Glu Trp Lys Ala Ile Gln Asn Lys Asp Arg Ala Lys Val Glu Phe
                 275                 280                 285

 Asn Ile Arg Lys Pro Asn Glu Gly Ala Asp Gly Gln Trp Lys Lys
                 290                 295                 300

 Gly Phe Val Leu His Lys Ser Lys Ser Glu Glu Ala His Ala Glu
                 305                 310                 315

 Asp Ser Val Met Asp His His Phe Arg Lys Pro Ala Asn Asp Ile
                 320                 325                 330

 Thr Ser Gln Leu Glu Ile Asn Phe Gly Asp Leu Gly Arg Pro Gly
                 335                 340                 345

 Arg Gly Gly Arg Gly Gly Arg Gly Gly Arg Gly Arg Gly Gly Arg
                 350                 355                 360

 Pro Asn Arg Gly Ser Arg Thr Asp Lys Ser Ser Ala Ser Ala Pro
                 365                 370                 375

 Asp Val Asp Asp Pro Glu Ala Phe Pro Ala Leu Ala
                 380                 385

<210> 3056
<211> 1843
<212> DNA
<213> Homo sapien

<400> 3056
 gcgagatccc taccgcagta gccgcctctg ccgccgcgga gcttcccgaa 50

 cctctcagcc gcccggagcc gctcccggag cccggccgta gaggctgcaa 100

 tcgcagccgg gagcccgcag cccgcgcccc gagcccgccg ccgcccttcg 150

 agggcgcccc aggccgcgcc atggtgaagg tgacgttcaa ctccgctctg 200

 gcccagaagg aggccaagaa ggacgagccc aagagcggcg aggaggcgct 250

 catcatcccc cccgacgccg tcgcggtgga ctgcaaggac ccagatgatg 300

 tggtaccagt tggccaaaga agagcctggt gttggtgcat gtgctttgga 350

 ctagcattta tgcttgcagg tgttattcta ggaggagcat acttgtacaa 400

 atattttgca cttcaaccag atgacgtgta ctactgtgga ataaagtaca 450

 tcaaagatga tgtcatctta aatgagccct ctgcagatgc cccagctgct 500

 ctctaccaga caattgaaga aaatattaaa atctttgaag aagaagaagt 550

 tgaatttatc agtgtgcctg tcccagagtt tgcagatagt gatcctgcca 600

 acattgttca tgactttaac aagaaactta cagcctattt agatcttaac 650

 ctggataagt gctatgtgat ccctctgaac acttccattg ttatgccacc 700

 cagaaaccta ctggagttac ttattaacat caaggctgga acctatttgc 750

 ctcagtccta tctgattcat gagcacatgg ttattactga tcgcattgaa 800

 aacattgatc acctgggttt ctttatttat cgactgtgtc atgacaagga 850

 aacttacaaa ctgcaacgca gagaaactat taaaggtatt cagaaacgtg 900

 aagccagcaa ttgtttcgca attcggcatt ttgaaaacaa atttgccgtg 950

 gaaactttaa tttgttcttg aacagtcaag aaaaacatta ttgaggaaaa 1000

 ttaatatcac agcataaccc caccctttac attttgtgca gtgattattt 1050

 tttaaagtct tctttcatgt aagtagcaaa cagggcttta ctatcttttc 1100

 atctcattaa ttcaattaaa accattacct taaaattttt ttctttcgaa 1150

 gtgtggtgtc ttttatattt gaattagtaa ctgtatgaag tcatagataa 1200

 tagtacatgt caccttaggt agtaggaaga attacaattt ctttaaatca 1250

 tttatctgga tttttatgtt ttattagcat tttcaagaag acggattatc 1300

 tagagaataa tcatatatat gcatacgtaa aaatggacca cagtgactta 1350

 tttgtagttg ttagttgccc tgctacctag tttgttagtg catttgagca 1400

 cacattttaa ttttcctcta attaaaatgt gcagtatttt cagtgtcaaa 1450

 tatatttaac tatttagaga atgatttcca cctttatgtt ttaatatcct 1500

 aggcatctgc tgtaataata ttttagaaaa tgtttggaat ttaagaaata 1550

 acttgtgtta ctaatttgta taacccatat ctgtgcaatg gaatataaat 1600

 atcacaaagt tgtttaacta gactgcgtgt tgtttttccc gtataataaa 1650

 accaaagaat agtttggttc ttcaaatctt aagagaatcc acataaaaga 1700

 agaaactatt ttttaaaaat tcacttctat atatacaatg agtaaaatca 1750

 cagatttttt ctttaaataa aaataagtca ttttaataac taaaccagat 1800

 tctttgtgga tactattaaa gtaacattta agcctcaacc ttg 1843

<210> 3057
<211> 266
<212> PRT
<213> Homo sapien

<400> 3057
 Met Val Lys Val Thr Phe Asn Ser Ala Leu Ala Gln Lys Glu Ala
   1               5                  10                  15

 Lys Lys Asp Glu Pro Lys Ser Gly Glu Glu Ala Leu Ile Ile Pro
                  20                  25                  30

 Pro Asp Ala Val Ala Val Asp Cys Lys Asp Pro Asp Asp Val Val
                  35                  40                  45

 Pro Val Gly Gln Arg Arg Ala Trp Cys Trp Cys Met Cys Phe Gly
                  50                  55                  60

 Leu Ala Phe Met Leu Ala Gly Val Ile Leu Gly Gly Ala Tyr Leu
                  65                  70                  75

 Tyr Lys Tyr Phe Ala Leu Gln Pro Asp Asp Val Tyr Tyr Cys Gly
                  80                  85                  90

 Ile Lys Tyr Ile Lys Asp Asp Val Ile Leu Asn Glu Pro Ser Ala
                  95                 100                 105

 Asp Ala Pro Ala Ala Leu Tyr Gln Thr Ile Glu Glu Asn Ile Lys
                 110                 115                 120

 Ile Phe Glu Glu Glu Glu Val Glu Phe Ile Ser Val Pro Val Pro
                 125                 130                 135

 Glu Phe Ala Asp Ser Asp Pro Ala Asn Ile Val His Asp Phe Asn
                 140                 145                 150

 Lys Lys Leu Thr Ala Tyr Leu Asp Leu Asn Leu Asp Lys Cys Tyr
                 155                 160                 165

 Val Ile Pro Leu Asn Thr Ser Ile Val Met Pro Pro Arg Asn Leu
                 170                 175                 180

 Leu Glu Leu Leu Ile Asn Ile Lys Ala Gly Thr Tyr Leu Pro Gln
                 185                 190                 195

 Ser Tyr Leu Ile His Glu His Met Val Ile Thr Asp Arg Ile Glu
                 200                 205                 210

 Asn Ile Asp His Leu Gly Phe Phe Ile Tyr Arg Leu Cys His Asp
                 215                 220                 225

 Lys Glu Thr Tyr Lys Leu Gln Arg Arg Glu Thr Ile Lys Gly Ile
                 230                 235                 240

 Gln Lys Arg Glu Ala Ser Asn Cys Phe Ala Ile Arg His Phe Glu
                 245                 250                 255

 Asn Lys Phe Ala Val Glu Thr Leu Ile Cys Ser
                 260                 265

<210> 3058
<211> 1843
<212> DNA
<213> Homo sapien

<400> 3058
 gcgagatccc taccgcagta gccgcctctg ccgccgcgga gcttcccgaa 50

 cctctcagcc gcccggagcc gctcccggag cccggccgta gaggctgcaa 100

 tcgcagccgg gagcccgcag cccgcgcccc gagcccgccg ccgcccttcg 150

 agggcgcccc aggccgcgcc atggtgaagg tgacgttcaa ctccgctctg 200

 gcccagaagg aggccaagaa ggacgagccc aagagcggcg aggaggcgct 250

 catcatcccc cccgacgccg tcgcggtgga ctgcaaggac ccagatgatg 300

 tggtaccagt tggccaaaga agagcctggt gttggtgcat gtgctttgga 350

 ctagcattta tgcttgcagg tgttattcta ggaggagcat acttgtacaa 400

 atattttgca cttcaaccag atgacgtgta ctactgtgga ataaagtaca 450

 tcaaagatga tgtcatctta aatgagccct ctgcagatgc cccagctgct 500

 ctctaccaga caattgaaga aaatattaaa atctttgaag aagaagaagt 550

 tgaatttatc agtgtgcctg tcccagagtt tgcagatagt gatcctgcca 600

 acattgttca tgactttaac aagaaactta cagcctattt agatcttaac 650

 ctggataagt gctatgtgat ccctctgaac acttccattg ttatgccacc 700

 cagaaaccta ctggagttac ttattaacat caaggctgga acctatttgc 750

 ctcagtccta tctgattcat gagcacatgg ttattactga tcgcattgaa 800

 aacattgatc acctgggttt ctttatttat cgactgtgtc atgacaagga 850

 aacttacaaa ctgcaacgca gagaaactat taaaggtatt cagaaacgtg 900

 aagccagcaa ttgtttcgca attcggcatt ttgaaaacaa atttgccgtg 950

 gaaactttaa tttgttcttg aacagtcaag aaaaacatta ttgaggaaaa 1000

 ttaatatcac agcataaccc caccctttac attttgtgca gtgattattt 1050

 tttaaagtct tctttcatgt aagtagcaaa cagggcttta ctatcttttc 1100

 atctcattaa ttcaattaaa accattacct taaaattttt ttctttcgaa 1150

 gtgtggtgtc ttttatattt gaattagtaa ctgtatgaag tcatagataa 1200

 tagtacatgt caccttaggt agtaggaaga attacaattt ctttaaatca 1250

 tttatctgga tttttatgtt ttattagcat tttcaagaag acggattatc 1300

 tagagaataa tcatatatat gcatacgtaa aaatggacca cagtgactta 1350

 tttgtagttg ttagttgccc tgctacctag tttgttagtg catttgagca 1400

 cacattttaa ttttcctcta attaaaatgt gcagtatttt cagtgtcaaa 1450

 tatatttaac tatttagaga atgatttcca cctttatgtt ttaatatcct 1500

 aggcatctgc tgtaataata ttttagaaaa tgtttggaat ttaagaaata 1550

 acttgtgtta ctaatttgta taacccatat ctgtgcaatg gaatataaat 1600

 atcacaaagt tgtttaacta gactgcgtgt tgtttttccc gtataataaa 1650

 accaaagaat agtttggttc ttcaaatctt aagagaatcc acataaaaga 1700

 agaaactatt ttttaaaaat tcacttctat atatacaatg agtaaaatca 1750

 cagatttttt ctttaaataa aaataagtca ttttaataac taaaccagat 1800

 tctttgtgga tactattaaa gtaacattta agcctcaacc ttg 1843

<210> 3059
<211> 266
<212> PRT
<213> Homo sapien

<400> 3059
 Met Val Lys Val Thr Phe Asn Ser Ala Leu Ala Gln Lys Glu Ala
   1               5                  10                  15

 Lys Lys Asp Glu Pro Lys Ser Gly Glu Glu Ala Leu Ile Ile Pro
                  20                  25                  30

 Pro Asp Ala Val Ala Val Asp Cys Lys Asp Pro Asp Asp Val Val
                  35                  40                  45

 Pro Val Gly Gln Arg Arg Ala Trp Cys Trp Cys Met Cys Phe Gly
                  50                  55                  60

 Leu Ala Phe Met Leu Ala Gly Val Ile Leu Gly Gly Ala Tyr Leu
                  65                  70                  75

 Tyr Lys Tyr Phe Ala Leu Gln Pro Asp Asp Val Tyr Tyr Cys Gly
                  80                  85                  90

 Ile Lys Tyr Ile Lys Asp Asp Val Ile Leu Asn Glu Pro Ser Ala
                  95                 100                 105

 Asp Ala Pro Ala Ala Leu Tyr Gln Thr Ile Glu Glu Asn Ile Lys
                 110                 115                 120

 Ile Phe Glu Glu Glu Glu Val Glu Phe Ile Ser Val Pro Val Pro
                 125                 130                 135

 Glu Phe Ala Asp Ser Asp Pro Ala Asn Ile Val His Asp Phe Asn
                 140                 145                 150

 Lys Lys Leu Thr Ala Tyr Leu Asp Leu Asn Leu Asp Lys Cys Tyr
                 155                 160                 165

 Val Ile Pro Leu Asn Thr Ser Ile Val Met Pro Pro Arg Asn Leu
                 170                 175                 180

 Leu Glu Leu Leu Ile Asn Ile Lys Ala Gly Thr Tyr Leu Pro Gln
                 185                 190                 195

 Ser Tyr Leu Ile His Glu His Met Val Ile Thr Asp Arg Ile Glu
                 200                 205                 210

 Asn Ile Asp His Leu Gly Phe Phe Ile Tyr Arg Leu Cys His Asp
                 215                 220                 225

 Lys Glu Thr Tyr Lys Leu Gln Arg Arg Glu Thr Ile Lys Gly Ile
                 230                 235                 240

 Gln Lys Arg Glu Ala Ser Asn Cys Phe Ala Ile Arg His Phe Glu
                 245                 250                 255

 Asn Lys Phe Ala Val Glu Thr Leu Ile Cys Ser
                 260                 265

<210> 3060
<211> 4575
<212> DNA
<213> Homo sapien

<400> 3060
 gcgccccgcc ctttctcggc ccccggaggt gacggggtga aggcggggga 50

 accgaggtgg ggagtccgcc agagctccca gactgcgagc acgcgagccg 100

 ccgcagccgt cacccgcgcc gcgtcacggc tcccgggccc gccctcctct 150

 gacccctccc ctctctccgt ttgcccctct ccccctcctc cgccgaccga 200

 gcagtgactt aagcaacgga gcgcggtgaa gctcattttt ctccttcctc 250

 gcagccgcgc cagggagctc gcggcgcgcg gcccctgtcc tccggcccga 300

 gatgaatcct gcggcagaag ccgagttcaa catcctcctg gccaccgact 350

 cctacaaggt tactcactat aaacaatatc cacccaacac aagcaaagtt 400

 tattcctact ttgaatgccg tgaaaagaag acagaaaact ccaaattaag 450

 gaaggtgaaa tatgaggaaa cagtatttta tgggttgcag tacattctta 500

 ataagtactt aaaaggtaaa gtagtaacca aagagaaaat ccaggaagcc 550

 aaagatgtct acaaagaaca tttccaagat gatgtcttta atgaaaaggg 600

 atggaactac attcttgaga agtatgatgg gcatcttcca atagaaataa 650

 aagctgttcc tgagggcttt gtcattccca gaggaaatgt tctcttcacg 700

 gtggaaaaca cagatccaga gtgttactgg cttacaaatt ggattgagac 750

 tattcttgtt cagtcctggt atccaatcac agtggccaca aattctagag 800

 agcagaagaa aatattggcc aaatatttgt tagaaacttc tggtaactta 850

 gatggtctgg aatacaagtt acatgatttt ggctacagag gagtctcttc 900

 ccaagagact gctggcatag gagcatctgc tcacttggtt aacttcaaag 950

 gaacagatac agtagcagga cttgctctaa ttaaaaaata ttatggaacg 1000

 aaagatcctg ttccaggcta ttctgttcca gcagcagaac acagtaccat 1050

 aacagcttgg gggaaagacc atgaaaaaga tgcttttgaa catattgtaa 1100

 cacagttttc atcagtgcct gtatctgtgg tcagcgatag ctatgacatt 1150

 tataatgcgt gtgagaaaat atggggtgaa gatctaagac atttaatagt 1200

 atcgagaagt acacaggcac cactaataat cagacctgat tctggaaacc 1250

 ctcttgacac tgtgttaaag gttttggaga ttttaggtaa gaagtttcct 1300

 gttactgaga actcaaaggg ttacaagttg ctgccacctt atcttagagt 1350

 tattcaaggg gatggagtag atattaatac cttacaagag attgtagaag 1400

 gcatgaaaca aaaaatgtgg agtattgaaa atattgcctt cggttctggt 1450

 ggaggtttgc tacagaagtt gacaagagat ctcttgaatt gttccttcaa 1500

 gtgtagctat gttgtaacta atggccttgg gattaacgtc ttcaaggacc 1550

 cagttgctga tcccaacaaa aggtccaaaa agggccgatt atctttacat 1600

 aggacgccag cagggaattt tgttacactg gaggaaggaa aaggagacct 1650

 tgaggaatat ggtcaggatc ttctccatac tgtcttcaag aatggcaagg 1700

 tgacaaaaag ctattcattt gatgaaataa gaaaaaatgc acagctgaat 1750

 attgaactgg aagcagcaca tcattaggct ttatgactgg gtgtgtgttg 1800

 tgtgtatgta atacataatg tttattgtac agatgtgtgg ggtttgtgtt 1850

 ttatgataca ttacagccaa attatttgtt ggtttatgga catactgccc 1900

 tttcattttt tttcttttcc agtgtttagg tgatctcaaa ttaggaaatg 1950

 catttaacca tgtaaaagat gagtgctaaa gtaagctttt tagggccctt 2000

 tgccaatagg tagtcattca atctggtatt gatcttttca caaataacag 2050

 aactgagaaa cttttatata taactgatga tcacataaaa cagatttgca 2100

 taaaattacc atgattgctt tatgtttata tttaacttgt atttttgtac 2150

 aaacaagatt gtgtaagata tatttgaagt ttcagtgatt taacagtctt 2200

 tccaactttt catgattttt atgagcacag actttcaaga aaatacttga 2250

 aaataaatta cattgccttt tgtccattaa tcagcaaata aaacatggcc 2300

 ttaacaaagt tgtttgtgtt attgtacaat ttgaaaatta tgtcgggaca 2350

 taccctatag aattactaac cttactgccc cttgtagaat atgtattaat 2400

 cattctacat taaagaaaat aatggttctt actggaatgt ctaggcactg 2450

 tacagttatt atatatcttg gttgttgtat tgtaccagtg aaatgccaaa 2500

 tttgaaaggc ctgtactgca attttatatg tcagagattg cctgtggctc 2550

 taatatgcac ctcaagattt taaggagata atgtttttag agagaatttc 2600

 tgcttccact atagaatata tacataaatg taaaatactt acaaaagtgg 2650

 aagtagtgta ttttaaagta attacacttc tgaatttatt tttcatattc 2700

 tatagttggt atgacttaaa tgaattactg gagtgggtag tgagtgtact 2750

 taaatgtttc aattctgtta tattttttat taagttttta aaaaattaaa 2800

 ttggatatta aattgtatgg acatcattta ttaattttaa actgaatgcc 2850

 ctcaataagt aatactgaag cacattctta aatgaagata aattatctcc 2900

 aatgaaaagc atgacatgtg tttcaataga agaatcttaa gttggctaaa 2950

 ttcaaagtgc ttgacatcaa aatgttctag agtgattagc tactagattc 3000

 tgaatcatac atcacatctg actagagacc agtttctttc gaatgattct 3050

 tttatgtatg tagatctgtt cttctgaggc agcggttggc caactatagc 3100

 ccaaaggcca aatttggact tctttttata aatgcagatt gtctatggct 3150

 gctttcccac tactccagcc taaggtaaac agctgcaata gaagccaaat 3200

 gagaatcgca aagcccaaaa tgtttattaa cctgcccttt acacaaaatc 3250

 acacaaaaag tttcctgatc tctgttctaa gaaaaggagt gtgccttgca 3300

 tttaaaagga aatgttggtt tctagggaag ggaggaggct aaataattga 3350

 tacggaattt tcctcttttg tcttcttttt tctcacttaa gaatccgata 3400

 ctggaagact gatttagaaa agtttttaac atgacattaa atgtgaaatt 3450

 ttaaaaattg aaaagccata aatcatctgt tttaaatagt tacatgagaa 3500

 aatgatcact agaataacct aattagaagt gttatcttca ttaaatgttt 3550

 tttgtaagtg gtattagaaa gaatatgttt ttcagatggt tctttaaaca 3600

 tgtagtgaga acaataagca ttattcactt ttagtaagtc ttctgtaatc 3650

 catgatataa aataatttta aaatgatttt ttaatgtatt tgagtaaaga 3700

 tgagtagtat taagaaaaac acacatttct tcacaaaatg tgctaagggg 3750

 cgtgtaaaga atcaaaagaa actattacca ataatagttt tgataatcac 3800

 ccataatttt gtgtttaaac attgaaatta tagtacagac agtattctct 3850

 gtgttctgtg aatttcagca gcttcagaat agagtttaat ttagaaattt 3900

 gcagtgaaaa aagctatctc tttgttcaca accataaatc aggagatgga 3950

 gattaattct attggctctt agtcacttgg aactgattaa ttctgacttt 4000

 ctgtcactaa gcacttggta tttggccatc tccattctga gcaccaaacg 4050

 gttaacacga atgtccacta gaactctgct gtgtgtcacc cttaaatcag 4100

 tctaaatctt ccagacaaaa gcaaatggca tttatggatt taagtcatta 4150

 gattttcaac tgacattaat taatccctct tgattgatta tatcatcaag 4200

 tatttatatc ttaaatagga ggtaggattt ctgtgttaag actcttattt 4250

 gtaccctata attaaagtaa aatgtttttt atgagtatcc cttgttttcc 4300

 cttcttaaat tgttatcaaa caatttttat aatgaaatct atcttggaaa 4350

 attagaaaga aaaatggcaa ggtatttatt gttctgtttg ccataattta 4400

 gaactcacac ttaagtattt tgtagtttta cattcctttt taacccattc 4450

 agtggagaat gtcagctttt ctcccaagtt gtatgttaag tctattctaa 4500

 tatgtactca acatcaagtt ataaacatgt aataaacatg gaaataaagt 4550

 ttagctctat tagtgaagtg ttaaa 4575

<210> 3061
<211> 491
<212> PRT
<213> Homo sapien

<400> 3061
 Met Asn Pro Ala Ala Glu Ala Glu Phe Asn Ile Leu Leu Ala Thr
   1               5                  10                  15

 Asp Ser Tyr Lys Val Thr His Tyr Lys Gln Tyr Pro Pro Asn Thr
                  20                  25                  30

 Ser Lys Val Tyr Ser Tyr Phe Glu Cys Arg Glu Lys Lys Thr Glu
                  35                  40                  45

 Asn Ser Lys Leu Arg Lys Val Lys Tyr Glu Glu Thr Val Phe Tyr
                  50                  55                  60

 Gly Leu Gln Tyr Ile Leu Asn Lys Tyr Leu Lys Gly Lys Val Val
                  65                  70                  75

 Thr Lys Glu Lys Ile Gln Glu Ala Lys Asp Val Tyr Lys Glu His
                  80                  85                  90

 Phe Gln Asp Asp Val Phe Asn Glu Lys Gly Trp Asn Tyr Ile Leu
                  95                 100                 105

 Glu Lys Tyr Asp Gly His Leu Pro Ile Glu Ile Lys Ala Val Pro
                 110                 115                 120

 Glu Gly Phe Val Ile Pro Arg Gly Asn Val Leu Phe Thr Val Glu
                 125                 130                 135

 Asn Thr Asp Pro Glu Cys Tyr Trp Leu Thr Asn Trp Ile Glu Thr
                 140                 145                 150

 Ile Leu Val Gln Ser Trp Tyr Pro Ile Thr Val Ala Thr Asn Ser
                 155                 160                 165

 Arg Glu Gln Lys Lys Ile Leu Ala Lys Tyr Leu Leu Glu Thr Ser
                 170                 175                 180

 Gly Asn Leu Asp Gly Leu Glu Tyr Lys Leu His Asp Phe Gly Tyr
                 185                 190                 195

 Arg Gly Val Ser Ser Gln Glu Thr Ala Gly Ile Gly Ala Ser Ala
                 200                 205                 210

 His Leu Val Asn Phe Lys Gly Thr Asp Thr Val Ala Gly Leu Ala
                 215                 220                 225

 Leu Ile Lys Lys Tyr Tyr Gly Thr Lys Asp Pro Val Pro Gly Tyr
                 230                 235                 240

 Ser Val Pro Ala Ala Glu His Ser Thr Ile Thr Ala Trp Gly Lys
                 245                 250                 255

 Asp His Glu Lys Asp Ala Phe Glu His Ile Val Thr Gln Phe Ser
                 260                 265                 270

 Ser Val Pro Val Ser Val Val Ser Asp Ser Tyr Asp Ile Tyr Asn
                 275                 280                 285

 Ala Cys Glu Lys Ile Trp Gly Glu Asp Leu Arg His Leu Ile Val
                 290                 295                 300

 Ser Arg Ser Thr Gln Ala Pro Leu Ile Ile Arg Pro Asp Ser Gly
                 305                 310                 315

 Asn Pro Leu Asp Thr Val Leu Lys Val Leu Glu Ile Leu Gly Lys
                 320                 325                 330

 Lys Phe Pro Val Thr Glu Asn Ser Lys Gly Tyr Lys Leu Leu Pro
                 335                 340                 345

 Pro Tyr Leu Arg Val Ile Gln Gly Asp Gly Val Asp Ile Asn Thr
                 350                 355                 360

 Leu Gln Glu Ile Val Glu Gly Met Lys Gln Lys Met Trp Ser Ile
                 365                 370                 375

 Glu Asn Ile Ala Phe Gly Ser Gly Gly Gly Leu Leu Gln Lys Leu
                 380                 385                 390

 Thr Arg Asp Leu Leu Asn Cys Ser Phe Lys Cys Ser Tyr Val Val
                 395                 400                 405

 Thr Asn Gly Leu Gly Ile Asn Val Phe Lys Asp Pro Val Ala Asp
                 410                 415                 420

 Pro Asn Lys Arg Ser Lys Lys Gly Arg Leu Ser Leu His Arg Thr
                 425                 430                 435

 Pro Ala Gly Asn Phe Val Thr Leu Glu Glu Gly Lys Gly Asp Leu
                 440                 445                 450

 Glu Glu Tyr Gly Gln Asp Leu Leu His Thr Val Phe Lys Asn Gly
                 455                 460                 465

 Lys Val Thr Lys Ser Tyr Ser Phe Asp Glu Ile Arg Lys Asn Ala
                 470                 475                 480

 Gln Leu Asn Ile Glu Leu Glu Ala Ala His His
                 485                 490

<210> 3062
<211> 2376
<212> DNA
<213> Homo sapien

<400> 3062
 cgcgcggccc ctgtcctccg gcccgagatg aatcctgcgg cagaagccga 50

 gttcaacatc ctcctggcca ccgactccta caaggttact cactataaac 100

 aatatccacc caacacaagc aaagtttatt cctactttga atgccgtgaa 150

 aagaagacag aaaactccaa attaaggaag gtgaaatatg aggaaacagt 200

 attttatggg ttgcagtaca ttcttaataa gtacttaaaa ggtaaagtag 250

 taaccaaaga gaaaatccag gaagccaaag atgtctacaa agaacatttc 300

 caagatgatg tctttaatga aaagggatgg aactacattc ttgagaagta 350

 tgatgggcat cttccaatag aaataaaagc tgttcctgag ggctttgtca 400

 ttcccagagg aaatgttctc ttcacggtgg aaaacacaga tccagagtgt 450

 tactggctta caaattggat tgagactatt cttgttcagt cctggtatcc 500

 aatcacagtg gccacaaatt ctagagagca gaagaaaata ttggccaaat 550

 atttgttaga aacttctggt aacttagatg gtctggaata caagttacat 600

 gattttggct acagaggagt ctcttcccaa gagactgctg gcataggagc 650

 atctgctcac ttggttaact tcaaaggaac agatacagta gcaggacttg 700

 ctctaattaa aaaatattat ggaacgaaag atcctgttcc aggctattct 750

 gttccagcag cagaacacag taccataaca gcttggggga aagaccatga 800

 aaaagatgct tttgaacata ttgtaacaca gttttcatca gtgcctgtat 850

 ctgtggtcag cgatagctat gacatttata atgcgtgtga gaaaatatgg 900

 ggtgaagatc taagacattt aatagtatcg agaagtacac aggcaccact 950

 aataatcaga cctgattctg gaaaccctct tgacactgtg ttaaaggttt 1000

 tggagatttt aggtaagaag tttcctgtta ctgagaactc aaagggttac 1050

 aagttgctgc caccttatct tagagttatt caaggggatg gagtagatat 1100

 taatacctta caagagattg tagaaggcat gaaacaaaaa atgtggagta 1150

 ttgaaaatat tgccttcggt tctggtggag gtttgctaca gaagttgaca 1200

 agagatctct tgaattgttc cttcaagtgt agctatgttg taactaatgg 1250

 ccttgggatt aacgtcttca aggacccagt tgctgatccc aacaaaaggt 1300

 ccaaaaaggg ccgattatct ttacatagga cgccagcagg gaattttgtt 1350

 acactggagg aaggaaaagg agaccttgag gaatatggtc aggatcttct 1400

 ccatactgtc ttcaagaatg gcaaggtgac aaaaagctat tcatttgatg 1450

 aaataagaaa aaatgcacag ctgaatattg aactggaagc agcacatcat 1500

 taggctttat gactgggtgt gtgttgtgtg tatgtaatac ataatgttta 1550

 ttgtacagat gtgtggggtt tgtgttttat gatacattac agccaaatta 1600

 tttgttggtt tatggacata ctgccctttc attttttttc ttttccagtg 1650

 tttaggtgat ctcaaattag gaaatgcatt taaccatgta aaagatgagt 1700

 gctaaagtaa gctttttagg gccctttgcc aataggtagt cattcaatct 1750

 ggtattgatc ttttcacaaa taacagaact gagaaacttt tatatataac 1800

 tgatgatcac ataaaacaga tttgcataaa attaccatga ttgctttatg 1850

 tttatattta acttgtattt ttgtacaaac aagattgtgt aagatatatt 1900

 tgaagtttca gtgatttaac agtctttcca acttttcatg atttttatga 1950

 gcacagactt tcaagaaaat acttgaaaat aaattacatt gccttttgtc 2000

 cattaatcag caaataaaac atggccttaa caaagttgtt tgtgttattg 2050

 tacaatttga aaattatgtc gggacatacc ctatagaatt actaacctta 2100

 ctgccccttg tagaatatgt attaatcatt ctacattaaa gaaaataatg 2150

 gttcttactg gaatgtctag gcactgtaca gttattatat atcttggttg 2200

 ttgtattgta ccagtgaaat gccaaatttg aaaggcctgt actgcaattt 2250

 tatatgtcag agattgcctg tggctctaat atgcacctca agattttaag 2300

 gagataatgt ttttagagag aatttctgct tccactatag aatatataca 2350

 taaatgtaaa atacttacaa aagtgg 2376

<210> 3063
<211> 491
<212> PRT
<213> Homo sapien

<400> 3063
 Met Asn Pro Ala Ala Glu Ala Glu Phe Asn Ile Leu Leu Ala Thr
   1               5                  10                  15

 Asp Ser Tyr Lys Val Thr His Tyr Lys Gln Tyr Pro Pro Asn Thr
                  20                  25                  30

 Ser Lys Val Tyr Ser Tyr Phe Glu Cys Arg Glu Lys Lys Thr Glu
                  35                  40                  45

 Asn Ser Lys Leu Arg Lys Val Lys Tyr Glu Glu Thr Val Phe Tyr
                  50                  55                  60

 Gly Leu Gln Tyr Ile Leu Asn Lys Tyr Leu Lys Gly Lys Val Val
                  65                  70                  75

 Thr Lys Glu Lys Ile Gln Glu Ala Lys Asp Val Tyr Lys Glu His
                  80                  85                  90

 Phe Gln Asp Asp Val Phe Asn Glu Lys Gly Trp Asn Tyr Ile Leu
                  95                 100                 105

 Glu Lys Tyr Asp Gly His Leu Pro Ile Glu Ile Lys Ala Val Pro
                 110                 115                 120

 Glu Gly Phe Val Ile Pro Arg Gly Asn Val Leu Phe Thr Val Glu
                 125                 130                 135

 Asn Thr Asp Pro Glu Cys Tyr Trp Leu Thr Asn Trp Ile Glu Thr
                 140                 145                 150

 Ile Leu Val Gln Ser Trp Tyr Pro Ile Thr Val Ala Thr Asn Ser
                 155                 160                 165

 Arg Glu Gln Lys Lys Ile Leu Ala Lys Tyr Leu Leu Glu Thr Ser
                 170                 175                 180

 Gly Asn Leu Asp Gly Leu Glu Tyr Lys Leu His Asp Phe Gly Tyr
                 185                 190                 195

 Arg Gly Val Ser Ser Gln Glu Thr Ala Gly Ile Gly Ala Ser Ala
                 200                 205                 210

 His Leu Val Asn Phe Lys Gly Thr Asp Thr Val Ala Gly Leu Ala
                 215                 220                 225

 Leu Ile Lys Lys Tyr Tyr Gly Thr Lys Asp Pro Val Pro Gly Tyr
                 230                 235                 240

 Ser Val Pro Ala Ala Glu His Ser Thr Ile Thr Ala Trp Gly Lys
                 245                 250                 255

 Asp His Glu Lys Asp Ala Phe Glu His Ile Val Thr Gln Phe Ser
                 260                 265                 270

 Ser Val Pro Val Ser Val Val Ser Asp Ser Tyr Asp Ile Tyr Asn
                 275                 280                 285

 Ala Cys Glu Lys Ile Trp Gly Glu Asp Leu Arg His Leu Ile Val
                 290                 295                 300

 Ser Arg Ser Thr Gln Ala Pro Leu Ile Ile Arg Pro Asp Ser Gly
                 305                 310                 315

 Asn Pro Leu Asp Thr Val Leu Lys Val Leu Glu Ile Leu Gly Lys
                 320                 325                 330

 Lys Phe Pro Val Thr Glu Asn Ser Lys Gly Tyr Lys Leu Leu Pro
                 335                 340                 345

 Pro Tyr Leu Arg Val Ile Gln Gly Asp Gly Val Asp Ile Asn Thr
                 350                 355                 360

 Leu Gln Glu Ile Val Glu Gly Met Lys Gln Lys Met Trp Ser Ile
                 365                 370                 375

 Glu Asn Ile Ala Phe Gly Ser Gly Gly Gly Leu Leu Gln Lys Leu
                 380                 385                 390

 Thr Arg Asp Leu Leu Asn Cys Ser Phe Lys Cys Ser Tyr Val Val
                 395                 400                 405

 Thr Asn Gly Leu Gly Ile Asn Val Phe Lys Asp Pro Val Ala Asp
                 410                 415                 420

 Pro Asn Lys Arg Ser Lys Lys Gly Arg Leu Ser Leu His Arg Thr
                 425                 430                 435

 Pro Ala Gly Asn Phe Val Thr Leu Glu Glu Gly Lys Gly Asp Leu
                 440                 445                 450

 Glu Glu Tyr Gly Gln Asp Leu Leu His Thr Val Phe Lys Asn Gly
                 455                 460                 465

 Lys Val Thr Lys Ser Tyr Ser Phe Asp Glu Ile Arg Lys Asn Ala
                 470                 475                 480

 Gln Leu Asn Ile Glu Leu Glu Ala Ala His His
                 485                 490

<210> 3064
<211> 1098
<212> DNA
<213> Homo sapien

<400> 3064
 cggcacgagg gtcccgcgcg ctcctccgac ccgctccgct ccgctccgct 50

 cggccccgcg ccgcccgtca acatgatccg ctgcggcctg gcctgcgagc 100

 gctgccgctg gatcctgccc ctgctcctac tcagcgccat cgccttcgac 150

 atcatcgcgc tggccggccg cggctggttg cagtctagcg accacggcca 200

 gacgtcctcg ctgtggtgga aatgctccca agagggcggc ggcagcgggt 250

 cctacgagga gggctgtcag agcctcatgg agtacgcgtg gggtagagca 300

 gcggctgcca tgctcttctg tggcttcatc atcctggtga tctgtttcat 350

 cctctccttc ttcgccctct gtggacccca gatgcttgtc ttcctgagag 400

 tgattggagg tctccttgcc ttggctgctg tgttccagat catctccctg 450

 gtaatttacc ccgtgaagta cacccagacc ttcacccttc atgccaaccc 500

 tgctgtcact tacatctata actgggccta cggctttggg tgggcagcca 550

 cgattatcct gattggctgt gccttcttct tctgctgcct cctcaactac 600

 gaagatgacc ttctgggcaa tgccaagccc aggtacttct acacatctgc 650

 ctaacttggg aatgaatgtg ggagaaaatc gctgctgctg agatggactc 700

 cagaagaaga aactgtttct ccaggcgact ttgaacccat tttttggcag 750

 tgttcatatt attaaactag tcaaaaatgc taaaataatt tgggagaaaa 800

 tattttttaa gtagtgttat agtttcatgt ttatctttta ttatgttttg 850

 tgaagttgtg tcttttcact aattacctat actatgccaa tatttcctta 900

 tatctatcca taacatttat actacatttg taagagaata tgcacgtgaa 950

 acttaacact ttataaggta aaaatgaggt ttccaagatt taataatctg 1000

 atcaagttct tgttatttcc aaatagaatg gactcggtct gttaagggct 1050

 aaggagaaga ggaagataag gttaaaagtt gttaatgacc aaacattc 1098

<210> 3065
<211> 193
<212> PRT
<213> Homo sapien

<400> 3065
 Met Ile Arg Cys Gly Leu Ala Cys Glu Arg Cys Arg Trp Ile Leu
   1               5                  10                  15

 Pro Leu Leu Leu Leu Ser Ala Ile Ala Phe Asp Ile Ile Ala Leu
                  20                  25                  30

 Ala Gly Arg Gly Trp Leu Gln Ser Ser Asp His Gly Gln Thr Ser
                  35                  40                  45

 Ser Leu Trp Trp Lys Cys Ser Gln Glu Gly Gly Gly Ser Gly Ser
                  50                  55                  60

 Tyr Glu Glu Gly Cys Gln Ser Leu Met Glu Tyr Ala Trp Gly Arg
                  65                  70                  75

 Ala Ala Ala Ala Met Leu Phe Cys Gly Phe Ile Ile Leu Val Ile
                  80                  85                  90

 Cys Phe Ile Leu Ser Phe Phe Ala Leu Cys Gly Pro Gln Met Leu
                  95                 100                 105

 Val Phe Leu Arg Val Ile Gly Gly Leu Leu Ala Leu Ala Ala Val
                 110                 115                 120

 Phe Gln Ile Ile Ser Leu Val Ile Tyr Pro Val Lys Tyr Thr Gln
                 125                 130                 135

 Thr Phe Thr Leu His Ala Asn Pro Ala Val Thr Tyr Ile Tyr Asn
                 140                 145                 150

 Trp Ala Tyr Gly Phe Gly Trp Ala Ala Thr Ile Ile Leu Ile Gly
                 155                 160                 165

 Cys Ala Phe Phe Phe Cys Cys Leu Leu Asn Tyr Glu Asp Asp Leu
                 170                 175                 180

 Leu Gly Asn Ala Lys Pro Arg Tyr Phe Tyr Thr Ser Ala
                 185                 190

<210> 3066
<211> 1017
<212> DNA
<213> Homo sapien

<400> 3066
 gaaaaggagc tcctgctgcc actgctcttc cggagcctgc agcatggggc 50

 ccctgccgcg caccgtggag ctcttctatg acgtgctgtc cccctactcc 100

 tggctgggct tcgagatcct gtgccggtat cagaatatct ggaacatcaa 150

 cctgcagttg cggcccagcc tcataacagg gatcatgaaa gacagtggaa 200

 acaagcctcc aggtctgctt ccccgcaaag gactatacat ggcaaatgac 250

 ttaaagctcc tgagacacca tctccagatt cccatccact tccccaagga 300

 tttcttgtct gtgatgcttg aaaaaggaag tttgtctgcc atgcgtttcc 350

 tcaccgccgt gaacttggag catccagaga tgctggagaa agcgtcccgg 400

 gagctgtgga tgcgcgtctg gtcaaggaat gaagacatca ccgagccgca 450

 gagcatcctg gcggctgcag agaaggctgg tatgtctgca gaacaagccc 500

 agggacttct ggaaaagatc gcaacgccaa aggtgaagaa ccagctcaag 550

 gagaccactg aggcagcctg cagatacgga gcctttgggt tgcccatcac 600

 cgtggcccat gtggatggcc aaacccacat gttatttggc tctgaccgga 650

 tggagctgct ggcgcacctg ctgggagaga agtggatggg ccctatacct 700

 ccagccgtga atgccagact ttaagattgc ccggaggaag caaactcttc 750

 gtataaaaaa agcaggccat ctgcttaacc cttggctcca ccataaggca 800

 ctgggactcg gatttctcta tctgatagag gtattttctg tggccctggg 850

 agctgtctgt ctttccccta cccccaagga tgccaggaag acgtccacca 900

 ttagccatgt ggcaaccttt acttctatgc ctcacaagtg cctttcagag 950

 agccccaatt ctgctttccc acaaaataaa cctaatgcca tcaggcaaaa 1000

 aaaaaaaaaa aaaaaaa 1017

<210> 3067
<211> 226
<212> PRT
<213> Homo sapien

<400> 3067
 Met Gly Pro Leu Pro Arg Thr Val Glu Leu Phe Tyr Asp Val Leu
   1               5                  10                  15

 Ser Pro Tyr Ser Trp Leu Gly Phe Glu Ile Leu Cys Arg Tyr Gln
                  20                  25                  30

 Asn Ile Trp Asn Ile Asn Leu Gln Leu Arg Pro Ser Leu Ile Thr
                  35                  40                  45

 Gly Ile Met Lys Asp Ser Gly Asn Lys Pro Pro Gly Leu Leu Pro
                  50                  55                  60

 Arg Lys Gly Leu Tyr Met Ala Asn Asp Leu Lys Leu Leu Arg His
                  65                  70                  75

 His Leu Gln Ile Pro Ile His Phe Pro Lys Asp Phe Leu Ser Val
                  80                  85                  90

 Met Leu Glu Lys Gly Ser Leu Ser Ala Met Arg Phe Leu Thr Ala
                  95                 100                 105

 Val Asn Leu Glu His Pro Glu Met Leu Glu Lys Ala Ser Arg Glu
                 110                 115                 120

 Leu Trp Met Arg Val Trp Ser Arg Asn Glu Asp Ile Thr Glu Pro
                 125                 130                 135

 Gln Ser Ile Leu Ala Ala Ala Glu Lys Ala Gly Met Ser Ala Glu
                 140                 145                 150

 Gln Ala Gln Gly Leu Leu Glu Lys Ile Ala Thr Pro Lys Val Lys
                 155                 160                 165

 Asn Gln Leu Lys Glu Thr Thr Glu Ala Ala Cys Arg Tyr Gly Ala
                 170                 175                 180

 Phe Gly Leu Pro Ile Thr Val Ala His Val Asp Gly Gln Thr His
                 185                 190                 195

 Met Leu Phe Gly Ser Asp Arg Met Glu Leu Leu Ala His Leu Leu
                 200                 205                 210

 Gly Glu Lys Trp Met Gly Pro Ile Pro Pro Ala Val Asn Ala Arg
                 215                 220                 225

 Leu


<210> 3068
<211> 2538
<212> DNA
<213> Homo sapien

<400> 3068
 gctggagcat cccgctctgg tgccgctgca gccggcagag atggttgagc 50

 tcatgttccc gctgttgctc ctccttctgc ccttccttct gtatatggct 100

 gcgccccaaa tcaggaaaat gctgtccagt ggggtgtgta catcaactgt 150

 tcagcttcct gggaaagtag ttgtggtcac aggagctaat acaggtatcg 200

 ggaaggagac agccaaagag ctggctcaga gaggagctcg agtatattta 250

 gcttgccggg atgtggaaaa gggggaattg gtggccaaag agatccagac 300

 cacgacaggg aaccagcagg tgttggtgcg gaaactggac ctgtctgata 350

 ctaagtctat tcgagctttt gctaagggct tcttagctga ggaaaagcac 400

 ctccacgttt tgatcaacaa tgcaggagtg atgatgtgtc cgtactcgaa 450

 gacagcagat ggctttgaga tgcacatagg agtcaaccac ttgggtcact 500

 tcctcctaac ccatctgctg ctagagaaac taaaggaatc agccccatca 550

 aggatagtaa atgtgtcttc cctcgcacat cacctgggaa ggatccactt 600

 ccataacctg cagggcgaga aattctacaa tgcaggcctg gcctactgtc 650

 acagcaagct agccaacatc ctcttcaccc aggaactggc ccggagacta 700

 aaaggctctg gcgttacgac gtattctgta caccctggca cagtccaatc 750

 tgaactggtt cggcactcat ctttcatgag atggatgtgg tggcttttct 800

 cctttttcat caagactcct cagcagggag cccagaccag cctgcactgt 850

 gccttaacag aaggtcttga gattctaagt gggaatcatt tcagtgactg 900

 tcatgtggca tgggtgtctg tccaagctcg taatgagact atagcaaggc 950

 ggctgtggga cgtcagttgt gacctgctgg gcctcccaat agactaacag 1000

 gcagtgccag ttggacccaa gagaagactg cagcagacta cacagtactt 1050

 cttgtcaaaa tgattctcct tcaaggtttt caaaaccttt agcacaaaga 1100

 gagcaaaacc ttccagcctt gcctgcttgg tgtccagtta aaactcagtg 1150

 tactgccaga ttcgtctaaa tgtctgtcat gtccagattt actttgcttc 1200

 tgttactgcc agagttacta gagatatcat aataggataa gaagaccctc 1250

 atatgacctg cacagctcat tttccttctg aaagaaacta ctacctagga 1300

 gaatctaagc tatagcaggg atgatttatg caaatttgaa ctagcttctt 1350

 tgttcacaat tcagttcctc ccaaccaacc agtcttcact tcaagagggc 1400

 cacactgcaa cctcagctta acatgaataa caaagactgg ctcaggagca 1450

 gggcttgccc aggcatggtg gatcaccgga ggtcagtagt tcaagaccag 1500

 cctggccaac atggtgaaac cccacctcta ctaaaaattg tgtatatctt 1550

 tgtgtgtctt cctgtttatg tgtgccaagg gagtattttc acaaagttca 1600

 aaacagccac aataatcaga gatggagcaa accagtgcca tccagtcttt 1650

 atgcaaatga aatgctgcaa agggaagcag attctgtata tgttggtaac 1700

 tacccaccaa gagcacatgg gtagcaggga agaagtaaaa aaagagaagg 1750

 agaatactgg aagataatgc acaaaatgaa gggactagtt aaggattaac 1800

 tagcccttta aggattaact agttaaggat taatagcaaa agatattaaa 1850

 tatgctaaca tagctatgga ggaattgagg gcaagcaccc aggactgatg 1900

 aggtcttaac aaaaaccagt gtggcaaaaa aaaaaaaaaa aaaaaaaaaa 1950

 aaaaatccta aaaacaaaca aacaaaaaaa acaattcttc attcagaaaa 2000

 attatcttag ggactgatat tggtaattat ggtcaattta ataatatttt 2050

 ggggcatttc cttacattgt cttgacaaga ttaaaatgtc tgtgccaaaa 2100

 ttttgtattt tatttggaga cttcttatca aaagtaatgc tgccaaagga 2150

 agtctaagga attagtagtg ttcccatcac ttgtttggag tgtgctattc 2200

 taaaagattt tgatttcctg gaatgacaat tatattttaa ctttggtggg 2250

 ggaaagagtt ataggaccac agtcttcact tctgatactt gtaaattaat 2300

 cttttattgc acttgttttg accattaagc tatatgttta gaaatggtca 2350

 ttttacggaa aaattagaaa aattctgata atagtgcaga ataaatgaat 2400

 taatgtttta cttaatttat attgaactgt caatgacaaa taaaaattct 2450

 ttttgattat tttttgtttt catttaccag aataaaaact aagaattaaa 2500

 agtttgatta cagtcaaaaa aaaaaaaaaa aaaaaaaa 2538

<210> 3069
<211> 318
<212> PRT
<213> Homo sapien

<400> 3069
 Met Val Glu Leu Met Phe Pro Leu Leu Leu Leu Leu Leu Pro Phe
   1               5                  10                  15

 Leu Leu Tyr Met Ala Ala Pro Gln Ile Arg Lys Met Leu Ser Ser
                  20                  25                  30

 Gly Val Cys Thr Ser Thr Val Gln Leu Pro Gly Lys Val Val Val
                  35                  40                  45

 Val Thr Gly Ala Asn Thr Gly Ile Gly Lys Glu Thr Ala Lys Glu
                  50                  55                  60

 Leu Ala Gln Arg Gly Ala Arg Val Tyr Leu Ala Cys Arg Asp Val
                  65                  70                  75

 Glu Lys Gly Glu Leu Val Ala Lys Glu Ile Gln Thr Thr Thr Gly
                  80                  85                  90

 Asn Gln Gln Val Leu Val Arg Lys Leu Asp Leu Ser Asp Thr Lys
                  95                 100                 105

 Ser Ile Arg Ala Phe Ala Lys Gly Phe Leu Ala Glu Glu Lys His
                 110                 115                 120

 Leu His Val Leu Ile Asn Asn Ala Gly Val Met Met Cys Pro Tyr
                 125                 130                 135

 Ser Lys Thr Ala Asp Gly Phe Glu Met His Ile Gly Val Asn His
                 140                 145                 150

 Leu Gly His Phe Leu Leu Thr His Leu Leu Leu Glu Lys Leu Lys
                 155                 160                 165

 Glu Ser Ala Pro Ser Arg Ile Val Asn Val Ser Ser Leu Ala His
                 170                 175                 180

 His Leu Gly Arg Ile His Phe His Asn Leu Gln Gly Glu Lys Phe
                 185                 190                 195

 Tyr Asn Ala Gly Leu Ala Tyr Cys His Ser Lys Leu Ala Asn Ile
                 200                 205                 210

 Leu Phe Thr Gln Glu Leu Ala Arg Arg Leu Lys Gly Ser Gly Val
                 215                 220                 225

 Thr Thr Tyr Ser Val His Pro Gly Thr Val Gln Ser Glu Leu Val
                 230                 235                 240

 Arg His Ser Ser Phe Met Arg Trp Met Trp Trp Leu Phe Ser Phe
                 245                 250                 255

 Phe Ile Lys Thr Pro Gln Gln Gly Ala Gln Thr Ser Leu His Cys
                 260                 265                 270

 Ala Leu Thr Glu Gly Leu Glu Ile Leu Ser Gly Asn His Phe Ser
                 275                 280                 285

 Asp Cys His Val Ala Trp Val Ser Val Gln Ala Arg Asn Glu Thr
                 290                 295                 300

 Ile Ala Arg Arg Leu Trp Asp Val Ser Cys Asp Leu Leu Gly Leu
                 305                 310                 315

 Pro Ile Asp


<210> 3070
<211> 2183
<212> DNA
<213> Homo sapien

<400> 3070
 ccagggcctg actaaacctg gagactcggg tggccgaggg gcttcatacc 50

 agctgaagag cgacaagccg ctggcagccg cggatctcac cgccgctcag 100

 ggtttttaga acttcagcca taaaaatggg cagaattttc cttgatcata 150

 tcggtggtac ccgtctgttt tcttgtgcaa actgtgatac gatcctgacc 200

 aaccgctcag aactcatctc cactcgtttc acaggcgcca ctggcagagc 250

 atttcttttt aacaaggtag ttaacctgca gtacagcgaa gttcaagatc 300

 gggtcatgct cactggccgc cacatggttc gagatgtgag ctgcaaaaac 350

 tgcaatagca aactgggatg gatctatgag tttgccactg aagacagcca 400

 gcgatataag gaaggccgcg tgatcctgga acgtgctcta gttcgagaga 450

 gtgagggctt tgaggagcat gtaccatctg ataactcttg aagatacaga 500

 gagaaatcca tcttttccca ggtctccttc actgaaaaca aaaatctact 550

 tacatacact gtcaccttag catcagagtc ggattaatga actgcggaac 600

 aagaggttgt gagaatctaa gatggaacct ttctttcttt ctttcttttt 650

 ttttaaattt tgtattttcc atccaacagc agtgtgtaga gagaatatta 700

 tgcagatgcc gttaattttt taccctatgt ttacatcttg aggcagcaga 750

 gtctgtctgc agctatgtgg tgagctatgt aaggaaaaaa atctgggctg 800

 ttagagtgaa aaagtgtgtt ttatgtcaat tgtgaaagga aaatgttagg 850

 agtatggttt ttaaacttgg gcttcatttt aaactttttt ttttaaaccc 900

 agttatttca cttgatttgc tagcttcaga gaagagatcc gaatctgtgc 950

 ccagcgctaa aggctcagtg ttagcatggc ttgtgctggc cggtgtgcca 1000

 tattcttgtt ggagatgaac cgtagcacca gagcccattc ttccttgtca 1050

 gtcttggccc aaagatgtca ccattcctag ttatttgtca ccacataatt 1100

 ggtgttgatt ggaaactttt tctgagatgg gacagaactg ctgggttgtc 1150

 tttttccatg taacttaagc atagtaatat aaataaagta atagttggat 1200

 gcttttggtc ctgtgttgct tttaaaaaca ccttataaaa gaggagagta 1250

 tttgataagc aattttcata gtagtaaagt tttttttcat ctcttaaact 1300

 aaattgacca tgcatataat attctttgtt taaatgaaag catactgttg 1350

 aaacccgcag tgttgcattt agaaaacagt tgaacagaat gtcaatgtgc 1400

 attcatgcaa aaaaacattt aatctgcatc tgttttagaa aagggggaaa 1450

 tgaagcaact tgtctaaaaa tactgcttta caaagcattt cagcctttcc 1500

 ccctcagttt tgcattgatt ttttgacaag tctgtagagc ctaatagttt 1550

 ccatcaaagg cctagatctc ttatttagca tttttttcag ctcttctctc 1600

 agaagttcag ctgttgaaac gaaaactgta ctttgtaccc tcacatacaa 1650

 agggatcaaa tttgacctgg tgttatttta gccccaaatt tatgacatta 1700

 cacaatatta aaatgtaaat gtttctttac ccaaactact tctagatatt 1750

 ctagtatttg cttctggtgg aattaaatga cggtaaaatt ggctaattat 1800

 ttgaatgaat gaatggatgg atgttttgca tgctcaattt ctaggtcctt 1850

 tgtctagaaa ggaaatttgc ctcagttgaa ttagtgaaat atttctgtcg 1900

 ttgatattaa aagtgacttc tgagtacagt taagttcctc ctatttgcca 1950

 ctgggctgtt ggttagaagc ataggtaact gattaagtag gtatgatact 2000

 gcatttgaaa taagtggaca caaactatcc tttctccacc atggactcaa 2050

 tctgagaaca acagcattca tttccattca tttccatact ggcttttgat 2100

 tatatgcaga ttcctagtag catgccttac ctacagcact atgtgcattt 2150

 gctgtcacaa taaagtatat tttgtcttgc aaa 2183

<210> 3071
<211> 121
<212> PRT
<213> Homo sapien

<400> 3071
 Met Gly Arg Ile Phe Leu Asp His Ile Gly Gly Thr Arg Leu Phe
   1               5                  10                  15

 Ser Cys Ala Asn Cys Asp Thr Ile Leu Thr Asn Arg Ser Glu Leu
                  20                  25                  30

 Ile Ser Thr Arg Phe Thr Gly Ala Thr Gly Arg Ala Phe Leu Phe
                  35                  40                  45

 Asn Lys Val Val Asn Leu Gln Tyr Ser Glu Val Gln Asp Arg Val
                  50                  55                  60

 Met Leu Thr Gly Arg His Met Val Arg Asp Val Ser Cys Lys Asn
                  65                  70                  75

 Cys Asn Ser Lys Leu Gly Trp Ile Tyr Glu Phe Ala Thr Glu Asp
                  80                  85                  90

 Ser Gln Arg Tyr Lys Glu Gly Arg Val Ile Leu Glu Arg Ala Leu
                  95                 100                 105

 Val Arg Glu Ser Glu Gly Phe Glu Glu His Val Pro Ser Asp Asn
                 110                 115                 120

 Ser


<210> 3072
<211> 2413
<212> DNA
<213> Homo sapien

<400> 3072
 gcgactcgtc ccgccttctg gggcactagt ttgactttgt gattggctac 50

 tagtatcaag gaatcccggc gtggacagcg cgaggagaaa gatggcggcg 100

 atggcggtcg ggggtgctgg tgggagccgc gtgtccagcg ggagggacct 150

 gaattgcgtc cccgaaatag ctgacacact aggggctgtg gccaagcagg 200

 ggtttgattt cctctgcatg cctgtcttcc atccgcgttt caagagggag 250

 ttcattcagg aacctgctaa gaatcggccc ggtccccaga cacgatcaga 300

 cctactgctg tcaggaaggg actggaatac gctaattgtg ggaaagcttt 350

 ctccatggat tcgtccagac tcaaaagtgg agaagattcg caggaactcc 400

 gaggcggcca tgttacagga gctgaatttt ggtgcatatt tgggtcttcc 450

 agctttcctg ctgcccctta atcaggaaga taacaccaac ctggccagag 500

 ttttgaccaa ccacatccac actggccatc actcttccat gttctggatg 550

 cgggtaccct tggtggcacc agaggacctg agagatgata taattgagaa 600

 tgcaccaact acacacacag aggagtacag tggggaggag aaaacgtgga 650

 tgtggtggca caacttccgg actttgtgtg actatagtaa gaggattgca 700

 gtggctcttg aaattggggc tgacctccca tctaatcatg tcattgatcg 750

 ctggcttggg gagcccatca aagcagccat tctccccact agcattttcc 800

 tgaccaataa gaagggattt cctgttcttt ctaagatgca ccagaggctc 850

 atcttccggc tcctcaagtt ggaggtgcag ttcatcatca caggcaccaa 900

 ccaccactca gagaaggagt tctgctccta cctccaatac ctggaatact 950

 taagccagaa ccgtcctcca cctaatgcct atgaactctt tgccaagggc 1000

 tatgaagact atctgcagtc cccgcttcag ccactgatgg acaatctgga 1050

 atctcagaca tatgaagtgt ttgaaaagga ccccatcaaa tactctcagt 1100

 accagcaggc catctataaa tgtctgctag accgagtacc agaagaggag 1150

 aaggatacca atgtccaggt actgatggtg ctgggagcag gacggggacc 1200

 cctggtgaac gcttccctgc gggcagccaa gcaggccgac cggcggataa 1250

 agctgtatgc tgtggagaaa aacccaaatg ccgtggtgac gctagagaac 1300

 tggcagtttg aagaatgggg aagccaagtg accgtagtct catcagacat 1350

 gagggaatgg gtggctccag agaaagcaga catcattgtc agtgagcttc 1400

 tgggctcatt tgctgacaat gaattgtcgc ctgagtgcct ggatggagcc 1450

 cagcacttcc taaaagatga tggtgtgagc atccccgggg agtacacttc 1500

 ctttctggct cccatctctt cctccaagct gtacaatgag gtccgagcct 1550

 gtagggagaa ggaccgtgac cctgaggccc agtttgagat gccttatgtg 1600

 gtacggctgc acaacttcca ccagctctct gcaccccagc cctgtttcac 1650

 cttcagccat cccaacagag atcctatgat tgacaacaac cgctattgca 1700

 ccttggaatt tcctgtggag gtgaacacag tactacatgg ctttgccggc 1750

 tactttgaga ctgtgcttta tcaggacatc actctgagta tccgtccaga 1800

 gactcactct cctgggatgt tctcatggtt tcccatcctc ttccctatta 1850

 agcagcccat aacggtacgt gaaggccaaa ccatctgtgt gcgtttctgg 1900

 cgatgcagca attccaagaa ggtgtggtat gagtgggctg tgacagcacc 1950

 agtctgttct gctattcata accccacagg ccgctcatat accattggcc 2000

 tctagccctg cgtgccaagt gtccagagcc ttggaagcag cttcaggttc 2050

 ctgctcctgt agtacagaag gtgcagtaca tctatgggct gtgattcccc 2100

 cttgcccatc agagaggagc atttcaatct gctttcctgc cttacatcaa 2150

 ggtgggcaag ggattataat taattgcagg gctcaagcca ccaatctatg 2200

 aagacctcag gccagggggt gaggaattag tgctggattt gaagctacgc 2250

 actcagcctc aagaactccc tggaatatcc ctgagaacat ggggtttgaa 2300

 cggattttca gcctttttct gttcttgttt tgatggtttt gtgtaagagg 2350

 aaataccaat aaagttatag ccctttactg ccaaaaaaaa aaaaaaaaaa 2400

 aaaaaaaaaa aaa 2413

<210> 3073
<211> 637
<212> PRT
<213> Homo sapien

<400> 3073
 Met Ala Ala Met Ala Val Gly Gly Ala Gly Gly Ser Arg Val Ser
   1               5                  10                  15

 Ser Gly Arg Asp Leu Asn Cys Val Pro Glu Ile Ala Asp Thr Leu
                  20                  25                  30

 Gly Ala Val Ala Lys Gln Gly Phe Asp Phe Leu Cys Met Pro Val
                  35                  40                  45

 Phe His Pro Arg Phe Lys Arg Glu Phe Ile Gln Glu Pro Ala Lys
                  50                  55                  60

 Asn Arg Pro Gly Pro Gln Thr Arg Ser Asp Leu Leu Leu Ser Gly
                  65                  70                  75

 Arg Asp Trp Asn Thr Leu Ile Val Gly Lys Leu Ser Pro Trp Ile
                  80                  85                  90

 Arg Pro Asp Ser Lys Val Glu Lys Ile Arg Arg Asn Ser Glu Ala
                  95                 100                 105

 Ala Met Leu Gln Glu Leu Asn Phe Gly Ala Tyr Leu Gly Leu Pro
                 110                 115                 120

 Ala Phe Leu Leu Pro Leu Asn Gln Glu Asp Asn Thr Asn Leu Ala
                 125                 130                 135

 Arg Val Leu Thr Asn His Ile His Thr Gly His His Ser Ser Met
                 140                 145                 150

 Phe Trp Met Arg Val Pro Leu Val Ala Pro Glu Asp Leu Arg Asp
                 155                 160                 165

 Asp Ile Ile Glu Asn Ala Pro Thr Thr His Thr Glu Glu Tyr Ser
                 170                 175                 180

 Gly Glu Glu Lys Thr Trp Met Trp Trp His Asn Phe Arg Thr Leu
                 185                 190                 195

 Cys Asp Tyr Ser Lys Arg Ile Ala Val Ala Leu Glu Ile Gly Ala
                 200                 205                 210

 Asp Leu Pro Ser Asn His Val Ile Asp Arg Trp Leu Gly Glu Pro
                 215                 220                 225

 Ile Lys Ala Ala Ile Leu Pro Thr Ser Ile Phe Leu Thr Asn Lys
                 230                 235                 240

 Lys Gly Phe Pro Val Leu Ser Lys Met His Gln Arg Leu Ile Phe
                 245                 250                 255

 Arg Leu Leu Lys Leu Glu Val Gln Phe Ile Ile Thr Gly Thr Asn
                 260                 265                 270

 His His Ser Glu Lys Glu Phe Cys Ser Tyr Leu Gln Tyr Leu Glu
                 275                 280                 285

 Tyr Leu Ser Gln Asn Arg Pro Pro Pro Asn Ala Tyr Glu Leu Phe
                 290                 295                 300

 Ala Lys Gly Tyr Glu Asp Tyr Leu Gln Ser Pro Leu Gln Pro Leu
                 305                 310                 315

 Met Asp Asn Leu Glu Ser Gln Thr Tyr Glu Val Phe Glu Lys Asp
                 320                 325                 330

 Pro Ile Lys Tyr Ser Gln Tyr Gln Gln Ala Ile Tyr Lys Cys Leu
                 335                 340                 345

 Leu Asp Arg Val Pro Glu Glu Glu Lys Asp Thr Asn Val Gln Val
                 350                 355                 360

 Leu Met Val Leu Gly Ala Gly Arg Gly Pro Leu Val Asn Ala Ser
                 365                 370                 375

 Leu Arg Ala Ala Lys Gln Ala Asp Arg Arg Ile Lys Leu Tyr Ala
                 380                 385                 390

 Val Glu Lys Asn Pro Asn Ala Val Val Thr Leu Glu Asn Trp Gln
                 395                 400                 405

 Phe Glu Glu Trp Gly Ser Gln Val Thr Val Val Ser Ser Asp Met
                 410                 415                 420

 Arg Glu Trp Val Ala Pro Glu Lys Ala Asp Ile Ile Val Ser Glu
                 425                 430                 435

 Leu Leu Gly Ser Phe Ala Asp Asn Glu Leu Ser Pro Glu Cys Leu
                 440                 445                 450

 Asp Gly Ala Gln His Phe Leu Lys Asp Asp Gly Val Ser Ile Pro
                 455                 460                 465

 Gly Glu Tyr Thr Ser Phe Leu Ala Pro Ile Ser Ser Ser Lys Leu
                 470                 475                 480

 Tyr Asn Glu Val Arg Ala Cys Arg Glu Lys Asp Arg Asp Pro Glu
                 485                 490                 495

 Ala Gln Phe Glu Met Pro Tyr Val Val Arg Leu His Asn Phe His
                 500                 505                 510

 Gln Leu Ser Ala Pro Gln Pro Cys Phe Thr Phe Ser His Pro Asn
                 515                 520                 525

 Arg Asp Pro Met Ile Asp Asn Asn Arg Tyr Cys Thr Leu Glu Phe
                 530                 535                 540

 Pro Val Glu Val Asn Thr Val Leu His Gly Phe Ala Gly Tyr Phe
                 545                 550                 555

 Glu Thr Val Leu Tyr Gln Asp Ile Thr Leu Ser Ile Arg Pro Glu
                 560                 565                 570

 Thr His Ser Pro Gly Met Phe Ser Trp Phe Pro Ile Leu Phe Pro
                 575                 580                 585

 Ile Lys Gln Pro Ile Thr Val Arg Glu Gly Gln Thr Ile Cys Val
                 590                 595                 600

 Arg Phe Trp Arg Cys Ser Asn Ser Lys Lys Val Trp Tyr Glu Trp
                 605                 610                 615

 Ala Val Thr Ala Pro Val Cys Ser Ala Ile His Asn Pro Thr Gly
                 620                 625                 630

 Arg Ser Tyr Thr Ile Gly Leu
                 635

<210> 3074
<211> 4447
<212> DNA
<213> Homo sapien

<400> 3074
 atgcggcggc gctcgcggat gctgctctgc ttcgccttcc tgtgggtgct 50

 gggcatcgcc tactacatgt actcgggggg cggctctgcg ctggccgggg 100

 gcgcgggcgg cggcgccggc aggaaggagg actggaatga aattgacccc 150

 attaaaaaga aagaccttca tcacagcaat ggagaagaga aagcacaaag 200

 catggagacc ctccctccag ggaaagtacg gtggccagac tttaaccagg 250

 aagcttatgt tggagggacg atggtccgct ccgggcagga cccttacgcc 300

 cgcaacaagt tcaaccaggt ggagagtgat aagcttcgaa tggacagagc 350

 catccctgac acccggcatg accagtgtca gcggaagcag tggcgggtgg 400

 atctgccggc caccagcgtg gtgatcacgt ttcacaatga agccaggtcg 450

 gccctactca ggaccgtggt cagcgtgctt aagaaaagcc cgccccatct 500

 cataaaagaa atcatcttgg tggatgacta cagcaatgat cctgaggacg 550

 gggctctctt ggggaaaatt gagaaagtgc gagttcttag aaatgatcga 600

 cgagaaggcc tcatgcgctc acgggttcgg ggggccgatg ctgcccaagc 650

 caaggtcctg accttcctgg acagtcactg cgagtgtaat gagcactggc 700

 tggagcccct cctggaaagg gtggcggagg acaggactcg ggttgtgtca 750

 cccatcatcg atgtcattaa tatggacaac tttcagtatg tgggggcatc 800

 tgctgacttg aagggcggtt ttgattggaa cttggtattc aagtgggatt 850

 acatgacgcc tgagcagaga aggtcccggc aggggaaccc agtcgcccct 900

 ataaaaaccc ccatgattgc tggtgggctg tttgtgatgg ataagttcta 950

 ttttgaagaa ctggggaagt acgacatgat gatggatgtg tggggaggag 1000

 agaacctaga gatctcgttc cgcgtgtggc agtgtggtgg cagcctggag 1050

 atcatcccgt gcagccgtgt gggacacgtg ttccggaagc agcaccccta 1100

 cacgttcccg ggtggcagtg gcactgtctt tgcccgaaac acccgccggg 1150

 cagcagaggt ctggatggat gaatacaaaa atttctatta tgcagcagtg 1200

 ccttctgcta gaaacgttcc ttatggaaat attcagagca gattggagct 1250

 taggaagaaa ctcagctgca agcctttcaa atggtacctt gaaaatgtct 1300

 atccagagtt aagggttcca gaccatcagg atatagcttt tggggccttg 1350

 cagcagggaa ctaactgcct cgacactttg ggacactttg ctgatggtgt 1400

 ggttggagtt tatgaatgtc acaatgctgg gggaaaccag gaatgggcct 1450

 tgacgaagga gaagtcggtg aagcacatgg atttgtgcct tactgtggtg 1500

 gaccgggcac cgggctctct tataaagctg cagggctgcc gagaaaatga 1550

 cagcagacag aaatgggaac agatcgaggg caactccaag ctgaggcacg 1600

 tgggcagcaa cctgtgcctg gacagtcgca cggccaagag cgggggccta 1650

 agcgtggagg tgtgtggccc ggccctttcg cagcagtgga agttcacgct 1700

 caacctgcag cagtaggagg gtccgggagg ccctgccgtc ctgtctcctg 1750

 caccattggg tggagtctgg tgatcgcatt attgattatg tttcttaaac 1800

 tttctgcgaa actaatatac ctcagtattc catcatggtc tgaaagtcaa 1850

 acttcggcaa ggcacggacg actgtgcaga cacatcagcg gcaagaagcg 1900

 agaactgccc tccccctcct ctcggtgcag ccagccgggc ccccttcccc 1950

 aggccggagc gcccctcttc cttccagctt tcacttctgc cggtccgcaa 2000

 ctgagtgaca cccagcgaca accgactggg gagtggtaga agcaactgaa 2050

 cggatgcgtg cgagctgagg acagggcggg aggaggggca cacatgcccc 2100

 aggggagcga ggagaactct tgaaatctcc attttcaatc ccttcgaaat 2150

 cacgtatggt ttccacaaag ccgagtcgtg tcacgtggca ggtttacgtc 2200

 aatagtccct ctctctgctc ctccattcgc aagtgtcttc ctgggccaga 2250

 ctcccctccc cctcatgtac ttgctatatt gaggatgaag ttttctatgg 2300

 tgggacacta aatataaagc tatatagaga aagaatgtac ggtcagttcc 2350

 ctatggtttc tgtagatcat cgtcatcttg tatattcccc acaaagccgt 2400

 tcgcagcttc cgggagaagg ggccagagcc cggtatgggg caagttctct 2450

 aacagaggga ggaggtggcc tttgtgtccc ctggaggccc ccggatccag 2500

 ccagttggtg ctactgctgt ggccagctgg ggggcttcct ccagaccacc 2550

 ggcctcggcc ccggcatccc tgttgggcgt cagcctgaga gtccctactg 2600

 tgcgtcagaa tccaccttgc gtgctgtgcg tatctgtgaa cctgggagac 2650

 ggttacttat tttgacagat atcactttgg gtctttttac attaaatttc 2700

 ttttctctaa ggaatataag acatacccca tagctctgtg tgagccagca 2750

 ataccgctgc cccctggcga cagggcagac caatgatgcc aggcagctgt 2800

 cacacgctag tattggcttc attgtgatct gagccctgca cgctgggcct 2850

 tcagaattaa tggccagcag tgtcagggat gagcccgtca gccagggcac 2900

 aggcctggct cacagtcctg cacacctgct ggcctggggg agctccagcc 2950

 aggcagcgag tcctgccccg cccgcagctc cctcccacac cccgcctggc 3000

 caagatgact gcttcagggg gctttgggga aagaattagg aagggtcaga 3050

 accaaacaat acctgctcat ttacactgag gattcagggc gggagacagg 3100

 agccttgggg tcctgttaaa ccacagacag ttatgaactg aaagtcataa 3150

 cggggagagg tgcctggctt ctacctgggt gctcaggaat gttcctcctc 3200

 acccctgcca ctctgtggtc ggtgccctgc ttcctcctcc actcctggcc 3250

 gccttctcca gcgccgcaca cacagatgct cagtctcaga gaggctggca 3300

 cggcctggca gtctgagaaa atcgtcagtt agccactgca ggccctcggt 3350

 gggacagcgg cggccttgga ttaggagcca cctgggagtg tgccggtgcc 3400

 atgctcctcc ctgtgtcttg tatgaaaggg ccactgtgtg tcttcctccc 3450

 cggcgggagc ccacatgttg cactgtagga cagcggcccg aagtggaagc 3500

 ctggctggag gctgccctat aggtctctct ccgcctcccc tgccatgcaa 3550

 ccagatgtgt gtgaatgggc cacgtgcccc cacgctggat actccgccac 3600

 gcttctgtct ttcacggtgg gcgctcgggg ggagctgaga aaacccctta 3650

 gtactgtgcg agctgtggag tgcaggccag agcagggtgt gcgtagcccc 3700

 cagcacccag gttcttctgt cagaccctgt gacctgcgag ctgctactac 3750

 tgtaaggagg gaaatggatg aatctggctc gttttaaaat cacgttttct 3800

 gacgaatcct ttgccccttc acctttaccc cgcccgcacc cctaggccct 3850

 ctcagccttc ctatcatccc acgtgtctac ccagaccctt gtgcggccca 3900

 tgccctgggg gcggcgtcct gtccctgagc tgggaggcgg ctttggatgg 3950

 tccgggcgtc aagagcaggg gtgggccggg gaggggtcct ttgcggtgag 4000

 ctatgtttac attgacacag tgtgccaaag tgacttactg cggttgcgtt 4050

 agtttctgtc atcaggacac tatctcaccc tcccactcct gtttttaaaa 4100

 ctcagaattc tttcctaaga gcccttcgaa gcaaagcgtg ccgaagttag 4150

 ttgtcttctc tgtgctggtc ctttcttatg tcctcataaa agctcagatg 4200

 atggtatctg tgagtatgtt ttgcaaattc aaaatatagt ttggtaattt 4250

 tttttgccag ttgattttta aaaagaactg ctgtacagag ctagtacttt 4300

 gtccatttta tgaatggaaa ccatccttga aaattgttta acttaaataa 4350

 agagaagata ctttctagat accgctcttt gctggccaga gtctgtcctg 4400

 gtgtgtgaag gctgggtggg gtgggtgtgg ggactgggat tggggtc 4447

<210> 3075
<211> 571
<212> PRT
<213> Homo sapien

<400> 3075
 Met Arg Arg Arg Ser Arg Met Leu Leu Cys Phe Ala Phe Leu Trp
   1               5                  10                  15

 Val Leu Gly Ile Ala Tyr Tyr Met Tyr Ser Gly Gly Gly Ser Ala
                  20                  25                  30

 Leu Ala Gly Gly Ala Gly Gly Gly Ala Gly Arg Lys Glu Asp Trp
                  35                  40                  45

 Asn Glu Ile Asp Pro Ile Lys Lys Lys Asp Leu His His Ser Asn
                  50                  55                  60

 Gly Glu Glu Lys Ala Gln Ser Met Glu Thr Leu Pro Pro Gly Lys
                  65                  70                  75

 Val Arg Trp Pro Asp Phe Asn Gln Glu Ala Tyr Val Gly Gly Thr
                  80                  85                  90

 Met Val Arg Ser Gly Gln Asp Pro Tyr Ala Arg Asn Lys Phe Asn
                  95                 100                 105

 Gln Val Glu Ser Asp Lys Leu Arg Met Asp Arg Ala Ile Pro Asp
                 110                 115                 120

 Thr Arg His Asp Gln Cys Gln Arg Lys Gln Trp Arg Val Asp Leu
                 125                 130                 135

 Pro Ala Thr Ser Val Val Ile Thr Phe His Asn Glu Ala Arg Ser
                 140                 145                 150

 Ala Leu Leu Arg Thr Val Val Ser Val Leu Lys Lys Ser Pro Pro
                 155                 160                 165

 His Leu Ile Lys Glu Ile Ile Leu Val Asp Asp Tyr Ser Asn Asp
                 170                 175                 180

 Pro Glu Asp Gly Ala Leu Leu Gly Lys Ile Glu Lys Val Arg Val
                 185                 190                 195

 Leu Arg Asn Asp Arg Arg Glu Gly Leu Met Arg Ser Arg Val Arg
                 200                 205                 210

 Gly Ala Asp Ala Ala Gln Ala Lys Val Leu Thr Phe Leu Asp Ser
                 215                 220                 225

 His Cys Glu Cys Asn Glu His Trp Leu Glu Pro Leu Leu Glu Arg
                 230                 235                 240

 Val Ala Glu Asp Arg Thr Arg Val Val Ser Pro Ile Ile Asp Val
                 245                 250                 255

 Ile Asn Met Asp Asn Phe Gln Tyr Val Gly Ala Ser Ala Asp Leu
                 260                 265                 270

 Lys Gly Gly Phe Asp Trp Asn Leu Val Phe Lys Trp Asp Tyr Met
                 275                 280                 285

 Thr Pro Glu Gln Arg Arg Ser Arg Gln Gly Asn Pro Val Ala Pro
                 290                 295                 300

 Ile Lys Thr Pro Met Ile Ala Gly Gly Leu Phe Val Met Asp Lys
                 305                 310                 315

 Phe Tyr Phe Glu Glu Leu Gly Lys Tyr Asp Met Met Met Asp Val
                 320                 325                 330

 Trp Gly Gly Glu Asn Leu Glu Ile Ser Phe Arg Val Trp Gln Cys
                 335                 340                 345

 Gly Gly Ser Leu Glu Ile Ile Pro Cys Ser Arg Val Gly His Val
                 350                 355                 360

 Phe Arg Lys Gln His Pro Tyr Thr Phe Pro Gly Gly Ser Gly Thr
                 365                 370                 375

 Val Phe Ala Arg Asn Thr Arg Arg Ala Ala Glu Val Trp Met Asp
                 380                 385                 390

 Glu Tyr Lys Asn Phe Tyr Tyr Ala Ala Val Pro Ser Ala Arg Asn
                 395                 400                 405

 Val Pro Tyr Gly Asn Ile Gln Ser Arg Leu Glu Leu Arg Lys Lys
                 410                 415                 420

 Leu Ser Cys Lys Pro Phe Lys Trp Tyr Leu Glu Asn Val Tyr Pro
                 425                 430                 435

 Glu Leu Arg Val Pro Asp His Gln Asp Ile Ala Phe Gly Ala Leu
                 440                 445                 450

 Gln Gln Gly Thr Asn Cys Leu Asp Thr Leu Gly His Phe Ala Asp
                 455                 460                 465

 Gly Val Val Gly Val Tyr Glu Cys His Asn Ala Gly Gly Asn Gln
                 470                 475                 480

 Glu Trp Ala Leu Thr Lys Glu Lys Ser Val Lys His Met Asp Leu
                 485                 490                 495

 Cys Leu Thr Val Val Asp Arg Ala Pro Gly Ser Leu Ile Lys Leu
                 500                 505                 510

 Gln Gly Cys Arg Glu Asn Asp Ser Arg Gln Lys Trp Glu Gln Ile
                 515                 520                 525

 Glu Gly Asn Ser Lys Leu Arg His Val Gly Ser Asn Leu Cys Leu
                 530                 535                 540

 Asp Ser Arg Thr Ala Lys Ser Gly Gly Leu Ser Val Glu Val Cys
                 545                 550                 555

 Gly Pro Ala Leu Ser Gln Gln Trp Lys Phe Thr Leu Asn Leu Gln
                 560                 565                 570

 Gln


<210> 3076
<211> 4447
<212> DNA
<213> Homo sapien

<400> 3076
 atgcggcggc gctcgcggat gctgctctgc ttcgccttcc tgtgggtgct 50

 gggcatcgcc tactacatgt actcgggggg cggctctgcg ctggccgggg 100

 gcgcgggcgg cggcgccggc aggaaggagg actggaatga aattgacccc 150

 attaaaaaga aagaccttca tcacagcaat ggagaagaga aagcacaaag 200

 catggagacc ctccctccag ggaaagtacg gtggccagac tttaaccagg 250

 aagcttatgt tggagggacg atggtccgct ccgggcagga cccttacgcc 300

 cgcaacaagt tcaaccaggt ggagagtgat aagcttcgaa tggacagagc 350

 catccctgac acccggcatg accagtgtca gcggaagcag tggcgggtgg 400

 atctgccggc caccagcgtg gtgatcacgt ttcacaatga agccaggtcg 450

 gccctactca ggaccgtggt cagcgtgctt aagaaaagcc cgccccatct 500

 cataaaagaa atcatcttgg tggatgacta cagcaatgat cctgaggacg 550

 gggctctctt ggggaaaatt gagaaagtgc gagttcttag aaatgatcga 600

 cgagaaggcc tcatgcgctc acgggttcgg ggggccgatg ctgcccaagc 650

 caaggtcctg accttcctgg acagtcactg cgagtgtaat gagcactggc 700

 tggagcccct cctggaaagg gtggcggagg acaggactcg ggttgtgtca 750

 cccatcatcg atgtcattaa tatggacaac tttcagtatg tgggggcatc 800

 tgctgacttg aagggcggtt ttgattggaa cttggtattc aagtgggatt 850

 acatgacgcc tgagcagaga aggtcccggc aggggaaccc agtcgcccct 900

 ataaaaaccc ccatgattgc tggtgggctg tttgtgatgg ataagttcta 950

 ttttgaagaa ctggggaagt acgacatgat gatggatgtg tggggaggag 1000

 agaacctaga gatctcgttc cgcgtgtggc agtgtggtgg cagcctggag 1050

 atcatcccgt gcagccgtgt gggacacgtg ttccggaagc agcaccccta 1100

 cacgttcccg ggtggcagtg gcactgtctt tgcccgaaac acccgccggg 1150

 cagcagaggt ctggatggat gaatacaaaa atttctatta tgcagcagtg 1200

 ccttctgcta gaaacgttcc ttatggaaat attcagagca gattggagct 1250

 taggaagaaa ctcagctgca agcctttcaa atggtacctt gaaaatgtct 1300

 atccagagtt aagggttcca gaccatcagg atatagcttt tggggccttg 1350

 cagcagggaa ctaactgcct cgacactttg ggacactttg ctgatggtgt 1400

 ggttggagtt tatgaatgtc acaatgctgg gggaaaccag gaatgggcct 1450

 tgacgaagga gaagtcggtg aagcacatgg atttgtgcct tactgtggtg 1500

 gaccgggcac cgggctctct tataaagctg cagggctgcc gagaaaatga 1550

 cagcagacag aaatgggaac agatcgaggg caactccaag ctgaggcacg 1600

 tgggcagcaa cctgtgcctg gacagtcgca cggccaagag cgggggccta 1650

 agcgtggagg tgtgtggccc ggccctttcg cagcagtgga agttcacgct 1700

 caacctgcag cagtaggagg gtccgggagg ccctgccgtc ctgtctcctg 1750

 caccattggg tggagtctgg tgatcgcatt attgattatg tttcttaaac 1800

 tttctgcgaa actaatatac ctcagtattc catcatggtc tgaaagtcaa 1850

 acttcggcaa ggcacggacg actgtgcaga cacatcagcg gcaagaagcg 1900

 agaactgccc tccccctcct ctcggtgcag ccagccgggc ccccttcccc 1950

 aggccggagc gcccctcttc cttccagctt tcacttctgc cggtccgcaa 2000

 ctgagtgaca cccagcgaca accgactggg gagtggtaga agcaactgaa 2050

 cggatgcgtg cgagctgagg acagggcggg aggaggggca cacatgcccc 2100

 aggggagcga ggagaactct tgaaatctcc attttcaatc ccttcgaaat 2150

 cacgtatggt ttccacaaag ccgagtcgtg tcacgtggca ggtttacgtc 2200

 aatagtccct ctctctgctc ctccattcgc aagtgtcttc ctgggccaga 2250

 ctcccctccc cctcatgtac ttgctatatt gaggatgaag ttttctatgg 2300

 tgggacacta aatataaagc tatatagaga aagaatgtac ggtcagttcc 2350

 ctatggtttc tgtagatcat cgtcatcttg tatattcccc acaaagccgt 2400

 tcgcagcttc cgggagaagg ggccagagcc cggtatgggg caagttctct 2450

 aacagaggga ggaggtggcc tttgtgtccc ctggaggccc ccggatccag 2500

 ccagttggtg ctactgctgt ggccagctgg ggggcttcct ccagaccacc 2550

 ggcctcggcc ccggcatccc tgttgggcgt cagcctgaga gtccctactg 2600

 tgcgtcagaa tccaccttgc gtgctgtgcg tatctgtgaa cctgggagac 2650

 ggttacttat tttgacagat atcactttgg gtctttttac attaaatttc 2700

 ttttctctaa ggaatataag acatacccca tagctctgtg tgagccagca 2750

 ataccgctgc cccctggcga cagggcagac caatgatgcc aggcagctgt 2800

 cacacgctag tattggcttc attgtgatct gagccctgca cgctgggcct 2850

 tcagaattaa tggccagcag tgtcagggat gagcccgtca gccagggcac 2900

 aggcctggct cacagtcctg cacacctgct ggcctggggg agctccagcc 2950

 aggcagcgag tcctgccccg cccgcagctc cctcccacac cccgcctggc 3000

 caagatgact gcttcagggg gctttgggga aagaattagg aagggtcaga 3050

 accaaacaat acctgctcat ttacactgag gattcagggc gggagacagg 3100

 agccttgggg tcctgttaaa ccacagacag ttatgaactg aaagtcataa 3150

 cggggagagg tgcctggctt ctacctgggt gctcaggaat gttcctcctc 3200

 acccctgcca ctctgtggtc ggtgccctgc ttcctcctcc actcctggcc 3250

 gccttctcca gcgccgcaca cacagatgct cagtctcaga gaggctggca 3300

 cggcctggca gtctgagaaa atcgtcagtt agccactgca ggccctcggt 3350

 gggacagcgg cggccttgga ttaggagcca cctgggagtg tgccggtgcc 3400

 atgctcctcc ctgtgtcttg tatgaaaggg ccactgtgtg tcttcctccc 3450

 cggcgggagc ccacatgttg cactgtagga cagcggcccg aagtggaagc 3500

 ctggctggag gctgccctat aggtctctct ccgcctcccc tgccatgcaa 3550

 ccagatgtgt gtgaatgggc cacgtgcccc cacgctggat actccgccac 3600

 gcttctgtct ttcacggtgg gcgctcgggg ggagctgaga aaacccctta 3650

 gtactgtgcg agctgtggag tgcaggccag agcagggtgt gcgtagcccc 3700

 cagcacccag gttcttctgt cagaccctgt gacctgcgag ctgctactac 3750

 tgtaaggagg gaaatggatg aatctggctc gttttaaaat cacgttttct 3800

 gacgaatcct ttgccccttc acctttaccc cgcccgcacc cctaggccct 3850

 ctcagccttc ctatcatccc acgtgtctac ccagaccctt gtgcggccca 3900

 tgccctgggg gcggcgtcct gtccctgagc tgggaggcgg ctttggatgg 3950

 tccgggcgtc aagagcaggg gtgggccggg gaggggtcct ttgcggtgag 4000

 ctatgtttac attgacacag tgtgccaaag tgacttactg cggttgcgtt 4050

 agtttctgtc atcaggacac tatctcaccc tcccactcct gtttttaaaa 4100

 ctcagaattc tttcctaaga gcccttcgaa gcaaagcgtg ccgaagttag 4150

 ttgtcttctc tgtgctggtc ctttcttatg tcctcataaa agctcagatg 4200

 atggtatctg tgagtatgtt ttgcaaattc aaaatatagt ttggtaattt 4250

 tttttgccag ttgattttta aaaagaactg ctgtacagag ctagtacttt 4300

 gtccatttta tgaatggaaa ccatccttga aaattgttta acttaaataa 4350

 agagaagata ctttctagat accgctcttt gctggccaga gtctgtcctg 4400

 gtgtgtgaag gctgggtggg gtgggtgtgg ggactgggat tggggtc 4447

<210> 3077
<211> 571
<212> PRT
<213> Homo sapien

<400> 3077
 Met Arg Arg Arg Ser Arg Met Leu Leu Cys Phe Ala Phe Leu Trp
   1               5                  10                  15

 Val Leu Gly Ile Ala Tyr Tyr Met Tyr Ser Gly Gly Gly Ser Ala
                  20                  25                  30

 Leu Ala Gly Gly Ala Gly Gly Gly Ala Gly Arg Lys Glu Asp Trp
                  35                  40                  45

 Asn Glu Ile Asp Pro Ile Lys Lys Lys Asp Leu His His Ser Asn
                  50                  55                  60

 Gly Glu Glu Lys Ala Gln Ser Met Glu Thr Leu Pro Pro Gly Lys
                  65                  70                  75

 Val Arg Trp Pro Asp Phe Asn Gln Glu Ala Tyr Val Gly Gly Thr
                  80                  85                  90

 Met Val Arg Ser Gly Gln Asp Pro Tyr Ala Arg Asn Lys Phe Asn
                  95                 100                 105

 Gln Val Glu Ser Asp Lys Leu Arg Met Asp Arg Ala Ile Pro Asp
                 110                 115                 120

 Thr Arg His Asp Gln Cys Gln Arg Lys Gln Trp Arg Val Asp Leu
                 125                 130                 135

 Pro Ala Thr Ser Val Val Ile Thr Phe His Asn Glu Ala Arg Ser
                 140                 145                 150

 Ala Leu Leu Arg Thr Val Val Ser Val Leu Lys Lys Ser Pro Pro
                 155                 160                 165

 His Leu Ile Lys Glu Ile Ile Leu Val Asp Asp Tyr Ser Asn Asp
                 170                 175                 180

 Pro Glu Asp Gly Ala Leu Leu Gly Lys Ile Glu Lys Val Arg Val
                 185                 190                 195

 Leu Arg Asn Asp Arg Arg Glu Gly Leu Met Arg Ser Arg Val Arg
                 200                 205                 210

 Gly Ala Asp Ala Ala Gln Ala Lys Val Leu Thr Phe Leu Asp Ser
                 215                 220                 225

 His Cys Glu Cys Asn Glu His Trp Leu Glu Pro Leu Leu Glu Arg
                 230                 235                 240

 Val Ala Glu Asp Arg Thr Arg Val Val Ser Pro Ile Ile Asp Val
                 245                 250                 255

 Ile Asn Met Asp Asn Phe Gln Tyr Val Gly Ala Ser Ala Asp Leu
                 260                 265                 270

 Lys Gly Gly Phe Asp Trp Asn Leu Val Phe Lys Trp Asp Tyr Met
                 275                 280                 285

 Thr Pro Glu Gln Arg Arg Ser Arg Gln Gly Asn Pro Val Ala Pro
                 290                 295                 300

 Ile Lys Thr Pro Met Ile Ala Gly Gly Leu Phe Val Met Asp Lys
                 305                 310                 315

 Phe Tyr Phe Glu Glu Leu Gly Lys Tyr Asp Met Met Met Asp Val
                 320                 325                 330

 Trp Gly Gly Glu Asn Leu Glu Ile Ser Phe Arg Val Trp Gln Cys
                 335                 340                 345

 Gly Gly Ser Leu Glu Ile Ile Pro Cys Ser Arg Val Gly His Val
                 350                 355                 360

 Phe Arg Lys Gln His Pro Tyr Thr Phe Pro Gly Gly Ser Gly Thr
                 365                 370                 375

 Val Phe Ala Arg Asn Thr Arg Arg Ala Ala Glu Val Trp Met Asp
                 380                 385                 390

 Glu Tyr Lys Asn Phe Tyr Tyr Ala Ala Val Pro Ser Ala Arg Asn
                 395                 400                 405

 Val Pro Tyr Gly Asn Ile Gln Ser Arg Leu Glu Leu Arg Lys Lys
                 410                 415                 420

 Leu Ser Cys Lys Pro Phe Lys Trp Tyr Leu Glu Asn Val Tyr Pro
                 425                 430                 435

 Glu Leu Arg Val Pro Asp His Gln Asp Ile Ala Phe Gly Ala Leu
                 440                 445                 450

 Gln Gln Gly Thr Asn Cys Leu Asp Thr Leu Gly His Phe Ala Asp
                 455                 460                 465

 Gly Val Val Gly Val Tyr Glu Cys His Asn Ala Gly Gly Asn Gln
                 470                 475                 480

 Glu Trp Ala Leu Thr Lys Glu Lys Ser Val Lys His Met Asp Leu
                 485                 490                 495

 Cys Leu Thr Val Val Asp Arg Ala Pro Gly Ser Leu Ile Lys Leu
                 500                 505                 510

 Gln Gly Cys Arg Glu Asn Asp Ser Arg Gln Lys Trp Glu Gln Ile
                 515                 520                 525

 Glu Gly Asn Ser Lys Leu Arg His Val Gly Ser Asn Leu Cys Leu
                 530                 535                 540

 Asp Ser Arg Thr Ala Lys Ser Gly Gly Leu Ser Val Glu Val Cys
                 545                 550                 555

 Gly Pro Ala Leu Ser Gln Gln Trp Lys Phe Thr Leu Asn Leu Gln
                 560                 565                 570

 Gln


<210> 3078
<211> 1494
<212> DNA
<213> Homo sapien

<400> 3078
 ctcgcgaaag ggcaggcatc gcggggctgg ccacttccgt acttccgctt 50

 tccggcccag ccagcgcccg cgatgactgc cactctccgc ccctacctga 100

 gtgccgtgcg ggccacattg caggctgccc tctgcctgga gaacttctcc 150

 tcccaggttg tggaacgaca caacaagccg gaagtggaag tcaggagtag 200

 caaagagctc ctgttacaac ctgtgaccat cagcaggaat gagaaggaaa 250

 aggttctgat tgagggctcc atcaactctg tccgggtcag cattgctgtg 300

 aaacaggctg atgagatcga gaagattttg tgccacaagt tcatgcgctt 350

 catgatgatg cgagcagaga acttctttat ccttcgaagg aagcctgtgg 400

 aggggtatga tatcagcttt ctgatcacca acttccacac agagcagatg 450

 tacaaacaca agttggtgga ctttgtgatc cacttcatgg aggagattga 500

 caaggagatc agtgagatga agctgtcagt caatgcccgt gcccgcattg 550

 tggctgaaga gttccttaag aatttttaaa ccatctggct ggatctcgtg 600

 gccttccccc tcagactacc catgtctcca cgaaggcgtc ctggagtcac 650

 tccccgagca gcgcggcggc ggcagggagt tgggttgggg tgggcatttg 700

 atgcgggagg tgggtggtgt gcttgctagc tgggcaagaa agcagcagtg 750

 gacctgcccc aaggccacac gtgcctggtc aggctggctt ctgatgttca 800

 gtcccctggg ccgggacaga ttttttttaa cgtcttgaaa cttaaactct 850

 gtgcttgtag gatactgtaa cctttttgtc tttttttttt tttttttttt 900

 taaacctcca cctccagtgg ctgtgactgg tcccagtgat tatacgttat 950

 tggttgctgt gggtctgggc gggcctggag ccagaaggcg acttattttt 1000

 tctctcctat gccaccccag gtggggaggg agggaggttt cagactccag 1050

 tttctccctt gcccttttat tcccaagcct ccttggcccc agtataagtg 1100

 ttgggaactc tctgccagct tcctgagttc tgcctaaaga tggcccccca 1150

 gcactggttg gggacaaggg ccaaattggt gaccaccagt catgcctagg 1200

 acctggggcc caaaagccgg gcaacctctg gctacagggg ccattgggtg 1250

 ccctcccagt tgagaggggc cgctgtttcg ccttgtccgt cagtgccagt 1300

 gcctgtgcca gaggtggcga ggtgagtcct ccagagcttc ctggccgggc 1350

 cctcctcctg cctgttctgg ctcctctgct cccacgctag ctgtcccttt 1400

 tctgattctg gtggatcctc cctcccctaa ttaaagtctc tttttgcccc 1450

 tttggggctg catgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1494

<210> 3079
<211> 168
<212> PRT
<213> Homo sapien

<400> 3079
 Met Thr Ala Thr Leu Arg Pro Tyr Leu Ser Ala Val Arg Ala Thr
   1               5                  10                  15

 Leu Gln Ala Ala Leu Cys Leu Glu Asn Phe Ser Ser Gln Val Val
                  20                  25                  30

 Glu Arg His Asn Lys Pro Glu Val Glu Val Arg Ser Ser Lys Glu
                  35                  40                  45

 Leu Leu Leu Gln Pro Val Thr Ile Ser Arg Asn Glu Lys Glu Lys
                  50                  55                  60

 Val Leu Ile Glu Gly Ser Ile Asn Ser Val Arg Val Ser Ile Ala
                  65                  70                  75

 Val Lys Gln Ala Asp Glu Ile Glu Lys Ile Leu Cys His Lys Phe
                  80                  85                  90

 Met Arg Phe Met Met Met Arg Ala Glu Asn Phe Phe Ile Leu Arg
                  95                 100                 105

 Arg Lys Pro Val Glu Gly Tyr Asp Ile Ser Phe Leu Ile Thr Asn
                 110                 115                 120

 Phe His Thr Glu Gln Met Tyr Lys His Lys Leu Val Asp Phe Val
                 125                 130                 135

 Ile His Phe Met Glu Glu Ile Asp Lys Glu Ile Ser Glu Met Lys
                 140                 145                 150

 Leu Ser Val Asn Ala Arg Ala Arg Ile Val Ala Glu Glu Phe Leu
                 155                 160                 165

 Lys Asn Phe


<210> 3080
<211> 3319
<212> DNA
<213> Homo sapien

<400> 3080
 ccacgcgtcc ggggagcagc gagcacgcgt ttcccgcaac ccgataccat 50

 cggacaggat ttctccgcct cagcccaacg gggagatctc tggaaacatg 100

 gctacagaac atgttaatgg aaatggtact gaagagccca tggatactac 150

 ttctgcagtt atccattcag aaaattttca gacattgctt gatgctggtt 200

 taccacagaa agttgctgaa aaactagatg aaatttacgt tgcagggcta 250

 gttgcacata gtgatttaga tgaaagagct attgaagctt taaaagaatt 300

 caatgaagac ggtgcattgg cagttcttca acagtttaaa gacagtgatc 350

 tctctcatgt tcagaacaaa agtgcctttt tatgtggagt catgaagact 400

 tacaggcaga gagaaaaaca agggaccaaa gtagcagatt ctagtaaagg 450

 accagatgag gcaaaaatta aggcactctt ggaaagaaca ggctacacac 500

 ttgatgtgac cactggacag aggaagtatg gaggaccacc tccagattcc 550

 gtttattcag gtcagcagcc ttctgttggc actgagatat ttgtgggaaa 600

 gatcccaaga gatctatttg aggatgaact tgttccatta tttgagaaag 650

 ctggacctat atgggatctt cgtctaatga tggatccact cactggtctc 700

 aatagaggtt atgcgtttgt cactttttgt acaaaagaag cagctcagga 750

 ggctgttaaa ctgtataata atcatgaaat tcgttctgga aaacatattg 800

 gtgtctgcat ctcagttgcc aacaataggc tttttgtggg ctctattcct 850

 aagagtaaaa ccaaggaaca gattcttgaa gaatttagca aagtaacaga 900

 gggtcttaca gacgtcattt tataccacca accggatgac aagaaaaaaa 950

 acagaggctt ttgctttctt gaatatgaag atcacaaaac agctgcccag 1000

 gtaaaagtgc tgtttgtacg caaccttgcc aatactgtaa cagaagagat 1050

 tttagaaaag gcatttagtc agtttgggaa actggaacga gtgaagaagt 1100

 taaaagatta tgcgttcatt cattttgatg agcgagatgg tgctgtcaag 1150

 gctatggaag aaatgaatgg caaagacttg gagggagaaa atattgaaat 1200

 tgtttttgcc aagccaccag atcagaaaag gaaagaaaga aaagctcaga 1250

 ggcaagcagc aaaaaatcaa atgtatgacg attactacta ttatggtcca 1300

 cctcatatgc cccctccaac aagaggtcga gggcgtggag gtagaggtgg 1350

 ttatggatat cctccagatt attatggata tgaagattat tatgattatt 1400

 atggttatga ttaccataac tatcgtggtg gatatgaaga tccatactat 1450

 ggttatgaag attttcaagt tggagctaga ggaaggggtg gtagaggagc 1500

 aaggggtgct gctccatcca gaggtcgtgg ggctgctcct ccccgcggta 1550

 gagccggtta ttcacagaga ggaggtcctg gatcagcaag aggcgttcga 1600

 ggtgcgagag gaggtgccca acaacaaaga ggccgcgggc agggaaaagg 1650

 ggtcgaggcc ggtcctgacc tgttacaatg aagactgact tgctatgtgg 1700

 gattacacca gaagcttgca gtggagtaat ggtaaggaaa tcaagcaacc 1750

 ttaaatatgt cggctgtata ggagcatatt ctattgcaga agaccttcct 1800

 atgaagatca tggaatcaaa tacgggacat tgaactaata cttggacttt 1850

 gatatgaatt tctttaacaa ttttctctgc agtgcaagtt attaaactaa 1900

 agctactcta ttttcaaaat gtgttccaac agaaatcctt cataactcct 1950

 agcatggtat cttaataaag aataaagttc ttttaaaaat ctgctctaag 2000

 tagatttttc ccctttttta aattaaggat cccaacagtg gtattttgaa 2050

 atattctctt gaatttgtgc atttaaattt tattgcagtg gtatagatga 2100

 atgccactga tggtatcctt aaattttatt tctgctcacc aaggttaatc 2150

 atgattgtct atatcttttt tatagtgatc acttttgaat tgtgttcaga 2200

 tatgcagttt caggtgtaat catcagagct ggttagtcag gcattccaga 2250

 tagtggttct tttcagaacc tttttaaaag ggttggttaa ctacctcagt 2300

 agcagaggat tgaactatac cctgtctgta ctgtacatag aaaatctttg 2350

 tagataaaag caaggcttgt taaatatgat atgagggtaa gattttaata 2400

 taccaaatgt aacattctta gttgccttta gtttcagagg cttgtaagac 2450

 ttcctcatga ccatcataac aggccttgct tttgtcgtat tttgtggctg 2500

 aaaaagcagc cttgcttctt cagatattgt agttatttgg atgtataata 2550

 gtttagcaag atgttacttt tgtaagacat cagatgttca aaaaagtgca 2600

 tccgaacttg tactaaatac tgcagtgtcc ctttataaaa agtcagacta 2650

 aaactgacaa ttgtacagcg aagcctgaca tttggatatt ttgaagtttt 2700

 ttcataaatc atagaaatta gtatatggct gtagtttagc tttttaggta 2750

 aaaggtatgt ttcattagtg catttcttcc tgctgatcac tgtaaacatg 2800

 tgaatcagct ttccatttct tatgcaggtc atgataactt gtagagtaga 2850

 gtacaatcat ttgtgctatg tttttaattt tctaaagcac cttgatgaca 2900

 gtgagtgtcc agtggtgaag catcctctat tgaaccaccc tcaaaaattt 2950

 ttttgccaag tcctaagttg atagcttaaa gtaaaaagtg aaaattatag 3000

 tttcattagg acttggtgta aagaaatccc ctcccccctt ccccaaaggg 3050

 atactgcagt tatatcacat acccaatagg caccacgatg aagatcagag 3100

 cttatactta attaaggttt tatacacacc agttccccag taaatgcaaa 3150

 tttaacaaga aaatcagaca tgtcatatgt tcaaaatgct catggcaaac 3200

 aatcattttg cattcctgca aataaaattg ttttatactg taagctggag 3250

 gcgagtgtaa cttatttttg taataaagtt tttatttttt tttaaaaaaa 3300

 aaaaaaaaaa aaaaaaaaa 3319

<210> 3081
<211> 527
<212> PRT
<213> Homo sapien

<400> 3081
 Met Ala Thr Glu His Val Asn Gly Asn Gly Thr Glu Glu Pro Met
   1               5                  10                  15

 Asp Thr Thr Ser Ala Val Ile His Ser Glu Asn Phe Gln Thr Leu
                  20                  25                  30

 Leu Asp Ala Gly Leu Pro Gln Lys Val Ala Glu Lys Leu Asp Glu
                  35                  40                  45

 Ile Tyr Val Ala Gly Leu Val Ala His Ser Asp Leu Asp Glu Arg
                  50                  55                  60

 Ala Ile Glu Ala Leu Lys Glu Phe Asn Glu Asp Gly Ala Leu Ala
                  65                  70                  75

 Val Leu Gln Gln Phe Lys Asp Ser Asp Leu Ser His Val Gln Asn
                  80                  85                  90

 Lys Ser Ala Phe Leu Cys Gly Val Met Lys Thr Tyr Arg Gln Arg
                  95                 100                 105

 Glu Lys Gln Gly Thr Lys Val Ala Asp Ser Ser Lys Gly Pro Asp
                 110                 115                 120

 Glu Ala Lys Ile Lys Ala Leu Leu Glu Arg Thr Gly Tyr Thr Leu
                 125                 130                 135

 Asp Val Thr Thr Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro Asp
                 140                 145                 150

 Ser Val Tyr Ser Gly Gln Gln Pro Ser Val Gly Thr Glu Ile Phe
                 155                 160                 165

 Val Gly Lys Ile Pro Arg Asp Leu Phe Glu Asp Glu Leu Val Pro
                 170                 175                 180

 Leu Phe Glu Lys Ala Gly Pro Ile Trp Asp Leu Arg Leu Met Met
                 185                 190                 195

 Asp Pro Leu Thr Gly Leu Asn Arg Gly Tyr Ala Phe Val Thr Phe
                 200                 205                 210

 Cys Thr Lys Glu Ala Ala Gln Glu Ala Val Lys Leu Tyr Asn Asn
                 215                 220                 225

 His Glu Ile Arg Ser Gly Lys His Ile Gly Val Cys Ile Ser Val
                 230                 235                 240

 Ala Asn Asn Arg Leu Phe Val Gly Ser Ile Pro Lys Ser Lys Thr
                 245                 250                 255

 Lys Glu Gln Ile Leu Glu Glu Phe Ser Lys Val Thr Glu Gly Leu
                 260                 265                 270

 Thr Asp Val Ile Leu Tyr His Gln Pro Asp Asp Lys Lys Lys Asn
                 275                 280                 285

 Arg Gly Phe Cys Phe Leu Glu Tyr Glu Asp His Lys Thr Ala Ala
                 290                 295                 300

 Gln Val Lys Val Leu Phe Val Arg Asn Leu Ala Asn Thr Val Thr
                 305                 310                 315

 Glu Glu Ile Leu Glu Lys Ala Phe Ser Gln Phe Gly Lys Leu Glu
                 320                 325                 330

 Arg Val Lys Lys Leu Lys Asp Tyr Ala Phe Ile His Phe Asp Glu
                 335                 340                 345

 Arg Asp Gly Ala Val Lys Ala Met Glu Glu Met Asn Gly Lys Asp
                 350                 355                 360

 Leu Glu Gly Glu Asn Ile Glu Ile Val Phe Ala Lys Pro Pro Asp
                 365                 370                 375

 Gln Lys Arg Lys Glu Arg Lys Ala Gln Arg Gln Ala Ala Lys Asn
                 380                 385                 390

 Gln Met Tyr Asp Asp Tyr Tyr Tyr Tyr Gly Pro Pro His Met Pro
                 395                 400                 405

 Pro Pro Thr Arg Gly Arg Gly Arg Gly Gly Arg Gly Gly Tyr Gly
                 410                 415                 420

 Tyr Pro Pro Asp Tyr Tyr Gly Tyr Glu Asp Tyr Tyr Asp Tyr Tyr
                 425                 430                 435

 Gly Tyr Asp Tyr His Asn Tyr Arg Gly Gly Tyr Glu Asp Pro Tyr
                 440                 445                 450

 Tyr Gly Tyr Glu Asp Phe Gln Val Gly Ala Arg Gly Arg Gly Gly
                 455                 460                 465

 Arg Gly Ala Arg Gly Ala Ala Pro Ser Arg Gly Arg Gly Ala Ala
                 470                 475                 480

 Pro Pro Arg Gly Arg Ala Gly Tyr Ser Gln Arg Gly Gly Pro Gly
                 485                 490                 495

 Ser Ala Arg Gly Val Arg Gly Ala Arg Gly Gly Ala Gln Gln Gln
                 500                 505                 510

 Arg Gly Arg Gly Gln Gly Lys Gly Val Glu Ala Gly Pro Asp Leu
                 515                 520                 525

 Leu Gln


<210> 3082
<211> 1941
<212> DNA
<213> Homo sapien

<400> 3082
 ctccactcgc gccggacaca gggagcagcg agcacgcgtt tcccgcaacc 50

 cgataccatc ggacaggatt tctccgcctc agcccaacgg ggagggctag 100

 ttgcacatag tgatttagat gaaagagcta ttgaagcttt aaaagaattc 150

 aatgaagacg gtgcattggc agttcttcaa cagtttaaag acagtgatct 200

 ctctcatgtt cagaacaaaa gtgccttttt atgtggagtc atgaagactt 250

 acaggcagag agaaaaacaa gggaccaaag tagcagattc tagtaaagga 300

 ccagatgagg caaaaattaa ggcactcttg gaaagaacag gctacacact 350

 tgatgtgacc actggacaga ggaagtatgg aggaccacct ccagattccg 400

 tttattcaga tatttgtggg aaagatccca agagatctat ttgaggatga 450

 acttgttcca ttatttgaga aagctggacc tatatgggat cttcgtctaa 500

 tgatggatcc actcactggt ctcaatagag gttatgcgtt tgtcactttt 550

 tgtacaaaag aagcagctca ggaggctgtt aaactgtata ataatcatga 600

 aattcgttct ggaaaacata ttggtgtctg catctcagtt gccaacaata 650

 ggctttttgt gggctctatt cctaagagta aaaccaagga acagattctt 700

 gaagaattta gcaaagtaac agagggtctt acagacgtca ttttatacca 750

 ccaaccggat gacaagaaaa aaaacagagg ctcttgcttt cttgaatatg 800

 aagatcacaa aacagctgcc caggcaaggc gtaggttaat gagtggtaaa 850

 gtcaaggtct gggggaatgt tggaactgtt gaatgggctg atcctataga 900

 agatcctgat cctgaggtta tggcaaaggt aaaagtgctg tttgtacgca 950

 accttgccaa tactgtaaca gaagagattt tagaaaaggc atttagtcag 1000

 tttgggaaac tggaacgagt gaagaagtta aaagattatg cgttcattca 1050

 ttttgatgag cgagatggtg ctgtcaaggc tatggaagaa atgaatggca 1100

 aagacttgga gggagaaaat attgaaattg tttttgccaa gccaccagat 1150

 cagaaaagga aagaaagaaa agctcagagg caagcagcaa aaaatcaaat 1200

 gtatgacgat tactactatt atggtccacc tcatatgccc cctccaacaa 1250

 gaggtcgagg gcgtggaggt agaggtggtt atggatatcc tccagattat 1300

 tatggatatg aagattatta tgattattat ggttatgatt accataacta 1350

 tcgtggtgga tatgaagatc catactatgg ttatgaagat tttcaagttg 1400

 gagctagagg aaggggtggt agaggagcaa ggggtgctgc tccatccaga 1450

 ggtcgtgggg ctgctcctcc ccgcggtaga gccggttatt cacagagagg 1500

 aggtcctgga tcagcaagag gcgttcgagg tgcgagagga ggtgcccaac 1550

 aacaaagagg ccgcgggcag ggaaaagggg tcgaggccgg tcctgacctg 1600

 ttacaatgaa gactgacttg ctatgtggga ttacaccaga agcttgcagt 1650

 ggagtaatgg taaggaaatc aagcaacctt aaatatgtcg gctgtatagg 1700

 agcatattct attgcagaag accttcctat gaagatcatg gaatcaaata 1750

 cgggacattg aactaatact tggactttga tatgaatttc tttaacaatt 1800

 ttctctgcag tgcaagttat taaactaaag ctactctatt ttcaaaatgt 1850

 gttccaacag aaatccttca taactcctag catggtatct taataaagaa 1900

 taaagttctt ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1941

<210> 3083
<211> 410
<212> PRT
<213> Homo sapien

<400> 3083
 Met Glu Asp His Leu Gln Ile Pro Phe Ile Gln Ile Phe Val Gly
   1               5                  10                  15

 Lys Ile Pro Arg Asp Leu Phe Glu Asp Glu Leu Val Pro Leu Phe
                  20                  25                  30

 Glu Lys Ala Gly Pro Ile Trp Asp Leu Arg Leu Met Met Asp Pro
                  35                  40                  45

 Leu Thr Gly Leu Asn Arg Gly Tyr Ala Phe Val Thr Phe Cys Thr
                  50                  55                  60

 Lys Glu Ala Ala Gln Glu Ala Val Lys Leu Tyr Asn Asn His Glu
                  65                  70                  75

 Ile Arg Ser Gly Lys His Ile Gly Val Cys Ile Ser Val Ala Asn
                  80                  85                  90

 Asn Arg Leu Phe Val Gly Ser Ile Pro Lys Ser Lys Thr Lys Glu
                  95                 100                 105

 Gln Ile Leu Glu Glu Phe Ser Lys Val Thr Glu Gly Leu Thr Asp
                 110                 115                 120

 Val Ile Leu Tyr His Gln Pro Asp Asp Lys Lys Lys Asn Arg Gly
                 125                 130                 135

 Ser Cys Phe Leu Glu Tyr Glu Asp His Lys Thr Ala Ala Gln Ala
                 140                 145                 150

 Arg Arg Arg Leu Met Ser Gly Lys Val Lys Val Trp Gly Asn Val
                 155                 160                 165

 Gly Thr Val Glu Trp Ala Asp Pro Ile Glu Asp Pro Asp Pro Glu
                 170                 175                 180

 Val Met Ala Lys Val Lys Val Leu Phe Val Arg Asn Leu Ala Asn
                 185                 190                 195

 Thr Val Thr Glu Glu Ile Leu Glu Lys Ala Phe Ser Gln Phe Gly
                 200                 205                 210

 Lys Leu Glu Arg Val Lys Lys Leu Lys Asp Tyr Ala Phe Ile His
                 215                 220                 225

 Phe Asp Glu Arg Asp Gly Ala Val Lys Ala Met Glu Glu Met Asn
                 230                 235                 240

 Gly Lys Asp Leu Glu Gly Glu Asn Ile Glu Ile Val Phe Ala Lys
                 245                 250                 255

 Pro Pro Asp Gln Lys Arg Lys Glu Arg Lys Ala Gln Arg Gln Ala
                 260                 265                 270

 Ala Lys Asn Gln Met Tyr Asp Asp Tyr Tyr Tyr Tyr Gly Pro Pro
                 275                 280                 285

 His Met Pro Pro Pro Thr Arg Gly Arg Gly Arg Gly Gly Arg Gly
                 290                 295                 300

 Gly Tyr Gly Tyr Pro Pro Asp Tyr Tyr Gly Tyr Glu Asp Tyr Tyr
                 305                 310                 315

 Asp Tyr Tyr Gly Tyr Asp Tyr His Asn Tyr Arg Gly Gly Tyr Glu
                 320                 325                 330

 Asp Pro Tyr Tyr Gly Tyr Glu Asp Phe Gln Val Gly Ala Arg Gly
                 335                 340                 345

 Arg Gly Gly Arg Gly Ala Arg Gly Ala Ala Pro Ser Arg Gly Arg
                 350                 355                 360

 Gly Ala Ala Pro Pro Arg Gly Arg Ala Gly Tyr Ser Gln Arg Gly
                 365                 370                 375

 Gly Pro Gly Ser Ala Arg Gly Val Arg Gly Ala Arg Gly Gly Ala
                 380                 385                 390

 Gln Gln Gln Arg Gly Arg Gly Gln Gly Lys Gly Val Glu Ala Gly
                 395                 400                 405

 Pro Asp Leu Leu Gln
                 410

<210> 3084
<211> 1833
<212> DNA
<213> Homo sapien

<400> 3084
 ggcacgagtg ggagtacagg actcgcctcc tcagggttcc ctgtgctgcc 50

 acttttcagc catggccaca agtgaacaga gtatctgcca agcccgggct 100

 tccgtgatgg tctacgatga caccagtaag aaatgggtac caatcaaacc 150

 tggccagcag ggattcagcc ggatcaacat ctaccacaac actgccagca 200

 acaccttcag agtcgttgga gtcaagttgc aggatcagca ggttgtgatc 250

 aattattcaa tcgtgaaagg gctgaagtac aatcaggcca cgccaacctt 300

 ccaccagtgg cgagatgccc gccaggtcta cggcttaaac tttgcaagta 350

 aagaagaggc aaccacgttc tccaatgcaa tgctgtttgc cctgaacatc 400

 atgaattccc aagaaggagg cccctccagc cagcgtcagg tgcagaatgg 450

 cccctctcct gatgagatgg acatccagag aagacaagtg atggagcagc 500

 accagcagca gcgtcaggaa tctctagaaa gaagaacctc ggccacaggg 550

 cccatcctcc caccaggaca tccttcatct gcagccagcg cccccgtctc 600

 atgtagtggg cctccaccgc cccccccacc cccagtccca cctccaccca 650

 ctggggctac cccacctccc ccacccccac tgccagccgg aggagcccag 700

 gggtccagcc acgacgagag ctccatgtca ggactggccg ctgccatagc 750

 tggggccaag ctgagaagag tccaacggcc agaagacgca tctggaggct 800

 ccagtcccag tgggacctca aagtccgatg ccaaccgggc aagcagcggg 850

 ggtggcggag gaggcctcat ggaggaaatg aacaaactgc tggccaagag 900

 gagaaaagca gcctcccagt cagacaagcc agccgagaag aaggaagatg 950

 aaagccaaat ggaagatcct agtacctccc cctctccggg gacccgagca 1000

 gccagccagc cacctaactc ctcagaggct ggccggaagc cctgggagcg 1050

 gagcaactcg gtggagaagc ctgtgtcctc gattctgtcc agaaccccgt 1100

 ctgtggcaaa gagccccgaa gctaagagcc cccttcagtc gcagcctcac 1150

 tctaggatga agcctgctgg gagcgtgaat gacatggccc tggatgcctt 1200

 cgacttggac cggatgaagc aggagatcct agaggaggtg gtgagagagc 1250

 tccacaaggt gaaggaggag atcatcgacg ccatcaggca ggagctgagt 1300

 gggatcagca ccacgtaagg ggccggcctc gctgcgctga ttcgtcgagc 1350

 ccatccggcg acagaggaca gccagaagcc cagccagccc cagactccag 1400

 tgcaccagag cacgcacagg agcctgggcg cgctgctgtg aaacgtcctg 1450

 acctgtgatc acacatgaca gtgaggaaac caagtgcaac tcctgggttt 1500

 ttttagattc tgcctgacac ggaacaccag gtctgctcgt cttttttgtg 1550

 ttttatattt gcttatttaa ggtacatttc tttgggtttc tagagacgcc 1600

 cctaagtcac ctgcttcatt agacggtttc caggttttct cccaggtgac 1650

 gctgttagcg cctcagctgg cggtgacagc cggcccagcg tggcgccacc 1700

 acacaccgca gagctgtcca ggcacagctc cgtccccagc gctcatggtg 1750

 ttgaaactgt ctgtcatgca ccacggtgtc tgtgtccaca cagtaataaa 1800

 cggtttactg tccgcaaaaa aaaaaaaaaa aaa 1833

<210> 3085
<211> 418
<212> PRT
<213> Homo sapien

<400> 3085
 Met Ala Thr Ser Glu Gln Ser Ile Cys Gln Ala Arg Ala Ser Val
   1               5                  10                  15

 Met Val Tyr Asp Asp Thr Ser Lys Lys Trp Val Pro Ile Lys Pro
                  20                  25                  30

 Gly Gln Gln Gly Phe Ser Arg Ile Asn Ile Tyr His Asn Thr Ala
                  35                  40                  45

 Ser Asn Thr Phe Arg Val Val Gly Val Lys Leu Gln Asp Gln Gln
                  50                  55                  60

 Val Val Ile Asn Tyr Ser Ile Val Lys Gly Leu Lys Tyr Asn Gln
                  65                  70                  75

 Ala Thr Pro Thr Phe His Gln Trp Arg Asp Ala Arg Gln Val Tyr
                  80                  85                  90

 Gly Leu Asn Phe Ala Ser Lys Glu Glu Ala Thr Thr Phe Ser Asn
                  95                 100                 105

 Ala Met Leu Phe Ala Leu Asn Ile Met Asn Ser Gln Glu Gly Gly
                 110                 115                 120

 Pro Ser Ser Gln Arg Gln Val Gln Asn Gly Pro Ser Pro Asp Glu
                 125                 130                 135

 Met Asp Ile Gln Arg Arg Gln Val Met Glu Gln His Gln Gln Gln
                 140                 145                 150

 Arg Gln Glu Ser Leu Glu Arg Arg Thr Ser Ala Thr Gly Pro Ile
                 155                 160                 165

 Leu Pro Pro Gly His Pro Ser Ser Ala Ala Ser Ala Pro Val Ser
                 170                 175                 180

 Cys Ser Gly Pro Pro Pro Pro Pro Pro Pro Pro Val Pro Pro Pro
                 185                 190                 195

 Pro Thr Gly Ala Thr Pro Pro Pro Pro Pro Pro Leu Pro Ala Gly
                 200                 205                 210

 Gly Ala Gln Gly Ser Ser His Asp Glu Ser Ser Met Ser Gly Leu
                 215                 220                 225

 Ala Ala Ala Ile Ala Gly Ala Lys Leu Arg Arg Val Gln Arg Pro
                 230                 235                 240

 Glu Asp Ala Ser Gly Gly Ser Ser Pro Ser Gly Thr Ser Lys Ser
                 245                 250                 255

 Asp Ala Asn Arg Ala Ser Ser Gly Gly Gly Gly Gly Gly Leu Met
                 260                 265                 270

 Glu Glu Met Asn Lys Leu Leu Ala Lys Arg Arg Lys Ala Ala Ser
                 275                 280                 285

 Gln Ser Asp Lys Pro Ala Glu Lys Lys Glu Asp Glu Ser Gln Met
                 290                 295                 300

 Glu Asp Pro Ser Thr Ser Pro Ser Pro Gly Thr Arg Ala Ala Ser
                 305                 310                 315

 Gln Pro Pro Asn Ser Ser Glu Ala Gly Arg Lys Pro Trp Glu Arg
                 320                 325                 330

 Ser Asn Ser Val Glu Lys Pro Val Ser Ser Ile Leu Ser Arg Thr
                 335                 340                 345

 Pro Ser Val Ala Lys Ser Pro Glu Ala Lys Ser Pro Leu Gln Ser
                 350                 355                 360

 Gln Pro His Ser Arg Met Lys Pro Ala Gly Ser Val Asn Asp Met
                 365                 370                 375

 Ala Leu Asp Ala Phe Asp Leu Asp Arg Met Lys Gln Glu Ile Leu
                 380                 385                 390

 Glu Glu Val Val Arg Glu Leu His Lys Val Lys Glu Glu Ile Ile
                 395                 400                 405

 Asp Ala Ile Arg Gln Glu Leu Ser Gly Ile Ser Thr Thr
                 410                 415

<210> 3086
<211> 1297
<212> DNA
<213> Homo sapien

<400> 3086
 gcgcaggcgt ggggctctct ccttgtcagt cggcgccgcg tgcgggctgg 50

 tggctctgtg gcagcggcgg cggcaggact ccggcactat gagcggcttc 100

 agcaccgagg agcgcgccgc gcccttctcc ctggagtacc gagtcttcct 150

 caaaaatgag aaaggacaat atatatctcc atttcatgat attccaattt 200

 atgcagataa ggatgtgttt cacatggtag ttgaagtacc acgctggtct 250

 aatgcaaaaa tggagattgc tacaaaggac cctttaaacc ctattaaaca 300

 agatgtgaaa aaaggaaaac ttcgctatgt tgcgaatttg ttcccgtata 350

 aaggatatat ctggaactat ggtgccatcc ctcagacttg ggaagaccca 400

 gggcacaatg ataaacatac tggctgttgt ggtgacaatg acccaattga 450

 tgtgtgtgaa attggaagca aggtatgtgc aagaggtgaa ataattggcg 500

 tgaaagttct aggcatattg gctatgattg acgaagggga aaccgactgg 550

 aaagtcattg ccattaatgt ggatgatcct gatgcagcca attataatga 600

 tatcaatgat gtcaaacggc tgaaacctgg ctacttagaa gctactgtgg 650

 actggtttag aaggtataag gttcctgatg gaaaaccaga aaatgagttt 700

 gcgtttaatg cagaatttaa agataaggac tttgccattg atattattaa 750

 aagcactcat gaccattgga aagcattagt gactaagaaa acgaatggaa 800

 aaggaatcag ttgcatgaat acaactttgt ctgagagccc cttcaagtgt 850

 gatcctgatg ctgccagagc cattgtggat gctttaccac caccctgtga 900

 atctgcctgc acagtaccaa cagacgtgga taagtggttc catcaccaga 950

 aaaactaatg agatttctct ggaatacaag ctgatattgc tacatcgtgt 1000

 tcatctggat gtattagaag taaaagtagt agcttttcaa agctttaaat 1050

 ttgtagaact catctaacta aagtaaattc tgctgtgact aatccaatat 1100

 actcagaatg ttatccatct aaagcatttt tcatatctca actaagataa 1150

 cttttagcac atgcttaaat atcaaagcag ttgtcatttg gaagtcactt 1200

 gtgaatagat gtgcaagggg agcacatatt ggatgtatat gttaccatat 1250

 gttaggaaat aaaattattt tgctgaaact tggaaaaaaa aaaaaaa 1297

<210> 3087
<211> 289
<212> PRT
<213> Homo sapien

<400> 3087
 Met Ser Gly Phe Ser Thr Glu Glu Arg Ala Ala Pro Phe Ser Leu
   1               5                  10                  15

 Glu Tyr Arg Val Phe Leu Lys Asn Glu Lys Gly Gln Tyr Ile Ser
                  20                  25                  30

 Pro Phe His Asp Ile Pro Ile Tyr Ala Asp Lys Asp Val Phe His
                  35                  40                  45

 Met Val Val Glu Val Pro Arg Trp Ser Asn Ala Lys Met Glu Ile
                  50                  55                  60

 Ala Thr Lys Asp Pro Leu Asn Pro Ile Lys Gln Asp Val Lys Lys
                  65                  70                  75

 Gly Lys Leu Arg Tyr Val Ala Asn Leu Phe Pro Tyr Lys Gly Tyr
                  80                  85                  90

 Ile Trp Asn Tyr Gly Ala Ile Pro Gln Thr Trp Glu Asp Pro Gly
                  95                 100                 105

 His Asn Asp Lys His Thr Gly Cys Cys Gly Asp Asn Asp Pro Ile
                 110                 115                 120

 Asp Val Cys Glu Ile Gly Ser Lys Val Cys Ala Arg Gly Glu Ile
                 125                 130                 135

 Ile Gly Val Lys Val Leu Gly Ile Leu Ala Met Ile Asp Glu Gly
                 140                 145                 150

 Glu Thr Asp Trp Lys Val Ile Ala Ile Asn Val Asp Asp Pro Asp
                 155                 160                 165

 Ala Ala Asn Tyr Asn Asp Ile Asn Asp Val Lys Arg Leu Lys Pro
                 170                 175                 180

 Gly Tyr Leu Glu Ala Thr Val Asp Trp Phe Arg Arg Tyr Lys Val
                 185                 190                 195

 Pro Asp Gly Lys Pro Glu Asn Glu Phe Ala Phe Asn Ala Glu Phe
                 200                 205                 210

 Lys Asp Lys Asp Phe Ala Ile Asp Ile Ile Lys Ser Thr His Asp
                 215                 220                 225

 His Trp Lys Ala Leu Val Thr Lys Lys Thr Asn Gly Lys Gly Ile
                 230                 235                 240

 Ser Cys Met Asn Thr Thr Leu Ser Glu Ser Pro Phe Lys Cys Asp
                 245                 250                 255

 Pro Asp Ala Ala Arg Ala Ile Val Asp Ala Leu Pro Pro Pro Cys
                 260                 265                 270

 Glu Ser Ala Cys Thr Val Pro Thr Asp Val Asp Lys Trp Phe His
                 275                 280                 285

 His Gln Lys Asn


<210> 3088
<211> 6702
<212> DNA
<213> Homo sapien

<400> 3088
 ccccgactag cccgacagtc cccgactagc ccgacagccc cagcaggatc 50

 tgcatcgtca tcgagccggc ccagcttctg aagggagatg tcatggtgaa 100

 atgctaccac aagaaatacc gctcggccac ccgtgacgtc attttccgcc 150

 tgcagtttca cactggggct gtgcagggct acgggctggt gtttgggaag 200

 gaggatctgg acaatgccag caaagatgac cgttttcctg actatgggaa 250

 ggttgaatta gtcttctctg ccacgcctga gaagattcaa gggtccgaac 300

 acttgtacaa cgaccacggt gtgattgtgg actacaacac aacagaccca 350

 ctgatacgct gggactcgta cgagaacctc agtgcagatg gagaagtgct 400

 acacacgcag ggccctgtcg atggcagcct ttacgcgaag gtgaggaaga 450

 aaagctcctc ggatcctggc atcccaggtg gcccccaggc aatcccggcc 500

 accaacagcc cagaccacag tgaccacacc ttgtctgtca gcagtgactc 550

 cggccactct acagcctctg ccaggacgga taagacggaa gagcgcctgg 600

 ccccaggaac caggaggggc ctgagtgccc aggagaaggc agagttggac 650

 cagctgctca gtggctttgg cctggaagat cctggaagct ccctcaagga 700

 aatgactgat gctcgaagca agtacagtgg gacccgccac gtggtgccag 750

 cccaggttca cgtgaatgga gacgctgctc tgaaggatcg ggagacagac 800

 attctggatg acgagatgcc ccaccacgac ctgcacagtg tggacagcct 850

 tgggaccctg tcctcctcgg aagggcctca gtcggcccac ctgggtccct 900

 tcacctgcca caagagcagc cagaactcac tcctatctga cggttttggc 950

 agcaacgttg gtgaagatcc gcagggcacc ctcgttccgg acctgggcct 1000

 tggcatggac ggcccctatg agcgggagcg gacttttggg agtcgagagc 1050

 ccaagcagcc ccagcccctg ctgagaaagc cctcagtgtc cgcccagatg 1100

 caggcctatg ggcagagcag ctactccaca cagacctggg tgcgccagca 1150

 gcagatggtt gtagctcacc agtatagctt cgccccagat ggggaggccc 1200

 ggctggtgag ccgctgccct gcagacaatc ctggcctcgt ccaggcccag 1250

 cccagagtgc cactcacccc cacccgaggg accagcagta gggtggctgt 1300

 ccagaggggt gtaggcagtg ggccacatcc ccctgacaca cagcagccct 1350

 ctcccagcaa agcgttcaaa cccaggtttc caggagacca ggttgtgaat 1400

 ggagccggcc cagagctgag cacaggcccc tccccaggct cgcccaccct 1450

 ggacatcgac cagtccatcg agcagctcaa caggctgatc ctggagctgg 1500

 atcccacctt cgagcccatc cctacccaca tgaacgccct cggtagccag 1550

 gccaatggct ctgtgtctcc agacagcgtg ggaggtgggc tccgggcaag 1600

 cagcaggctg cctgacacag gagagggccc cagcagggcc accgggcggc 1650

 aaggctcctc tgctgaacag cccctgggcg ggagactcag gaagctgagc 1700

 ctggggcagt acgacaacga tgctgggggg cagctgccct tctccaaatg 1750

 tgcatgggga aaggctggtg tggactatgc cccaaacctg ccgccattcc 1800

 cctcaccagc ggacgtcaaa gagacgatga cccctggcta tccccaggac 1850

 ctcgatatta tcgatggcag aattttaagt agcaaggagt ccatgtgttc 1900

 aactccagca tttcctgtgt ctccagagac accgtatgtg aaaacagcgc 1950

 tgcgccatcc tccgttcagc ccacctgagc ccccgctgag cagcccagcc 2000

 agtcagcaca aaggaggacg tgaaccacga agctgccctg agacgctcac 2050

 tcacgctgtg gggatgtcag agagccccat cggacccaaa tccacgatgc 2100

 tccgggctga tgcgtcctcg acgccctcct ttcagcaggc ttttgcttct 2150

 tcctgcacca tttccagcaa cggccctggg cagaggagag agagctcctc 2200

 ttctgcagaa cgccagtggg tggagagcag ccccaagccc atggtttccc 2250

 tgctggggag cggccggccc accggaagtc ccctcagcgc tgagttctcc 2300

 ggtaccagga aggactcccc agtgctgtcc tgcttcccgc cgtcagagct 2350

 ccaggctcct ttccacagcc atgagctgtc cctagcagag ccaccggact 2400

 ccctggcgcc tcccagcagc caggccttcc tgggcttcgg caccgcccca 2450

 gtgggaagtg gccttccgcc cgaggaggac ctgggggcct tgctggccaa 2500

 ttctcatgga gcgtcaccga cccccagcat cccgctgaca gcgacagggg 2550

 ctgccgacaa tggcttcctg tcccacaact ttctcacggt ggcgcctgga 2600

 cacagcagcc accacagtcc aggcctgcag ggccagggtg tgaccctgcc 2650

 cgggcagcca cccctccctg agaagaagcg ggcctcggag ggggatcgtt 2700

 ctttgggctc agtctctccc tcctccagtg gcttctccag cccgcacagc 2750

 gggagcacca tcagtatccc cttcccaaat gtccttcccg acttttccaa 2800

 ggcttcagaa gcggcctcac ctctgccaga tagtccaggt gataaacttg 2850

 tgatcgtgaa atttgttcaa gacacttcca agttctggta caaggcggat 2900

 atttcaagag aacaagccat cgccatgttg aaggacaagg agccgggctc 2950

 attcattgtt cgagacagcc attccttccg aggggcctat ggcctggcca 3000

 tgaaggtggc cacgccccca ccttcagtcc tgcagctgaa caagaaagct 3050

 ggagatttgg ccaatgaact cgtccggcac tttttgatcg agtgtacccc 3100

 gaagggagtg cggttgaaag ggtgctcgaa tgaaccatat ttcgggagcc 3150

 tgacggcctt ggtgtgccag cattccatca cgcccttggc cttgccgtgc 3200

 aagctgctta tcccagagag agatccattg gaggaaatag cagaaagttc 3250

 tccccagacg gcagccaatt cagcagctga gctgttgaag cagggggcag 3300

 cctgcaacgt gtggtacttg aactctgtgg agatggagtc cctcaccggc 3350

 caccaggcga tccagaaggc cctgagcatc accctggtcc aggagcctcc 3400

 acctgtgtcc acagttgtgc acttcaaggt gtcagcccag ggcatcaccc 3450

 tgacagacaa tcagaggaag ctcttcttcc ggaggcatta ccccgtgaac 3500

 agtgtgattt tctgtgcctt ggacccacaa gacaggaagt ggatcaaaga 3550

 tggcccttcc tcaaaagtct ttggatttgt ggcccggaag cagggcagtg 3600

 ccacggataa tgtgtgccac ctgtttgcag agcatgaccc tgagcagcct 3650

 gccagtgcca ttgtcaactt cgtatcaaag gtcatgattg gttccccaaa 3700

 gaaggtctga gaactcccct ccctccctgg acccaccgat gcctctcgaa 3750

 gccctggaga cagccgttgg gtgagggtgg ggcccccact ttttaccaaa 3800

 ctagtaaacc tgacattcca ggcccatgag gggaaagagg atcttccagc 3850

 tctgcaaaaa caagaacaaa caacatcacc gtgaattggc ctttcctgaa 3900

 agtgacttat ctgacacatc tctgtagcca catgcttttt gggtagaaga 3950

 agctgggcat gggtgcaccc caccccctag ggtccccatg ggaaagggac 4000

 atgcaaggaa acagcacaga acacgaggtg gtccccatgt ccctggcaca 4050

 ctagcattcc gggggatgag gaatccccag cccttgaggc agaggtgccg 4100

 agtgactgcc atgcttcgcc cgtccgcatg ggcgcttctg tccagctgca 4150

 cccgaggccg ggggtttccc tcacctcggt cttcccaaga tggagatgct 4200

 aacgaaactg agaagggggc gtatgtttga cgaaggtttg tgcaagtcag 4250

 gcccttctgg aacacagcag ggcctacaac gaggggcctt tgcgatgggc 4300

 tgtgaggatg ggggtggtgg gaagaattgg ccacgttaga gaccccatgc 4350

 caccccacca tggtgagtgc tctgtgcctc ctgctcacct gtggtgagct 4400

 gggcgagctg ggcgagctgg gcgagctggg ctggggagag cctgtgagga 4450

 ccgagaggag aaatgagaag aaggaacaaa aatattattt ctatgtaatt 4500

 tatattttac ttatgccaaa ttatttatga taatttgcca ttgctatact 4550

 gtaccagtgt caaatgctgc agcctgccaa gctgtgattt tgtgaggctt 4600

 gtccctatgt aggatgcacc gcaggcccct ggccactgaa agagtgtgca 4650

 gtggactgtg ggtctcccat atgcggtgcc gcccaaaggt ggctttgcct 4700

 caagcaacct accctgatgt tttactcatt ggaatgtttt tccccgattg 4750

 tggatgactt cttttctgat ggagagagtc caggagggat ggaaaactcc 4800

 tggatttaag ctcagcatcc cccacatggg cttttcgatc atcttcaggc 4850

 ctgaagctgc acgacctgaa gttcgcctgc atttatcagc cctctttgtg 4900

 ctgctccttg ccaccttggg gttcctgctg gggaccatgt gtggttgtgg 4950

 catgtgtgag cagaagggag gatgaggaaa aagagaagaa accccggtac 5000

 tgacaagctg tttttgagtg ccactgtttg ccatcatcta agccactgaa 5050

 tcaagtgtat ttcaggctta tttcaacatt ccaatgccct ggttttcctg 5100

 cttgaatctg ttcgtggtca aaggtttggg ggaatttgtg accctggaac 5150

 atccccagag tgaaagatgg agctgggcca catcagaata aggccttggc 5200

 cccatcctct cacagcctag gtgctctgca ggcatgctga ctgtcctgat 5250

 tgcgatccag cccgaaattc cctcctctgc tttcaaaagt caaatccccc 5300

 attcttaggc cacactggtg tcacaagctc ctgtcaggga gctggggttt 5350

 gggaatgtgc tttgtgaact ctgctttaaa gtgaggggcc gaggaaaact 5400

 tagaaacagg cagagttgga agcagccaaa tcacagtggg tgttgtgtgt 5450

 gtgtgcgtgt gtgcatgcgt gcgtgtatgc gtgtgtgaaa gcaggtggac 5500

 cattccactt tttagctcct attgatgcac caaaccaagt gcctcatttc 5550

 tgtgccaaat gtttgccttg gtcgttgtgg acctccttct ctaacttgcg 5600

 gtggcatgac tgtcaggagg tgctggcatt ttcagcagat cctcatgtgt 5650

 tgaccctgat gtctttagca gaggcctcta gcatctcggt ttttcatcca 5700

 ctgcaggaat gtggccacag ggagcagagg tttgtacttt ccccaagagg 5750

 tcctcatcct gagacggtct ctacccatgt ttaacccaaa gagtgcaggc 5800

 caggttcctt atccttctga tgaaggatga gagagctcat ttagaagtca 5850

 gagcaaacta gggtctcagt attgagaaac gcagcctgcc agggaatcac 5900

 agagacatcg gggtgcccgc gatggccctc atgaagccat gcctcgacgg 5950

 cattcaggaa gccctgcaaa cgtgcttttt gaactcattg gccaggtgtg 6000

 atttttacac aaggtaaacg tggtcaaggg catcggggaa tttgctccaa 6050

 gcagatagct ccctctgagg aaccaaagga agcaagtttc cacgatttct 6100

 gaagagctgg tataggaagt ttctttcttc cttttgtgtt acatgtgcat 6150

 taaacagaac aagctgtgtg tcatcacaga ttgtactgtg ggctcagaaa 6200

 ccgtgagaga gcccccaccg tggacaccgg ctctagggcc acaggaaaag 6250

 gaacgtttcc aggcattttg tctccagggc tcccgctgga caggcacgta 6300

 ctgccctggg gagtaaatgc ggagagttca cgaactgtgc ccaacgcatg 6350

 ttatagccag ggtcctacta actactcagt aaaagaacgt attgttgtat 6400

 tcctccagtg ttaagctata gccatgttaa aagtcactgt gcatttattc 6450

 tcagcatcaa ataccttgta acgtcttctc tgccttgtta gtgcatattt 6500

 ttacttttct gatactgtaa agaatatatc cagtatgtaa atgaatgttc 6550

 tataaatctt ttgtatagtc attttctctg ctccttaaat atcatctcta 6600

 ttcagagtat aataaaatta tgaacttggt aaaaaaaaaa aaaaaaaaaa 6650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 6700

 aa 6702

<210> 3089
<211> 1205
<212> PRT
<213> Homo sapien

<400> 3089
 Met Val Lys Cys Tyr His Lys Lys Tyr Arg Ser Ala Thr Arg Asp
   1               5                  10                  15

 Val Ile Phe Arg Leu Gln Phe His Thr Gly Ala Val Gln Gly Tyr
                  20                  25                  30

 Gly Leu Val Phe Gly Lys Glu Asp Leu Asp Asn Ala Ser Lys Asp
                  35                  40                  45

 Asp Arg Phe Pro Asp Tyr Gly Lys Val Glu Leu Val Phe Ser Ala
                  50                  55                  60

 Thr Pro Glu Lys Ile Gln Gly Ser Glu His Leu Tyr Asn Asp His
                  65                  70                  75

 Gly Val Ile Val Asp Tyr Asn Thr Thr Asp Pro Leu Ile Arg Trp
                  80                  85                  90

 Asp Ser Tyr Glu Asn Leu Ser Ala Asp Gly Glu Val Leu His Thr
                  95                 100                 105

 Gln Gly Pro Val Asp Gly Ser Leu Tyr Ala Lys Val Arg Lys Lys
                 110                 115                 120

 Ser Ser Ser Asp Pro Gly Ile Pro Gly Gly Pro Gln Ala Ile Pro
                 125                 130                 135

 Ala Thr Asn Ser Pro Asp His Ser Asp His Thr Leu Ser Val Ser
                 140                 145                 150

 Ser Asp Ser Gly His Ser Thr Ala Ser Ala Arg Thr Asp Lys Thr
                 155                 160                 165

 Glu Glu Arg Leu Ala Pro Gly Thr Arg Arg Gly Leu Ser Ala Gln
                 170                 175                 180

 Glu Lys Ala Glu Leu Asp Gln Leu Leu Ser Gly Phe Gly Leu Glu
                 185                 190                 195

 Asp Pro Gly Ser Ser Leu Lys Glu Met Thr Asp Ala Arg Ser Lys
                 200                 205                 210

 Tyr Ser Gly Thr Arg His Val Val Pro Ala Gln Val His Val Asn
                 215                 220                 225

 Gly Asp Ala Ala Leu Lys Asp Arg Glu Thr Asp Ile Leu Asp Asp
                 230                 235                 240

 Glu Met Pro His His Asp Leu His Ser Val Asp Ser Leu Gly Thr
                 245                 250                 255

 Leu Ser Ser Ser Glu Gly Pro Gln Ser Ala His Leu Gly Pro Phe
                 260                 265                 270

 Thr Cys His Lys Ser Ser Gln Asn Ser Leu Leu Ser Asp Gly Phe
                 275                 280                 285

 Gly Ser Asn Val Gly Glu Asp Pro Gln Gly Thr Leu Val Pro Asp
                 290                 295                 300

 Leu Gly Leu Gly Met Asp Gly Pro Tyr Glu Arg Glu Arg Thr Phe
                 305                 310                 315

 Gly Ser Arg Glu Pro Lys Gln Pro Gln Pro Leu Leu Arg Lys Pro
                 320                 325                 330

 Ser Val Ser Ala Gln Met Gln Ala Tyr Gly Gln Ser Ser Tyr Ser
                 335                 340                 345

 Thr Gln Thr Trp Val Arg Gln Gln Gln Met Val Val Ala His Gln
                 350                 355                 360

 Tyr Ser Phe Ala Pro Asp Gly Glu Ala Arg Leu Val Ser Arg Cys
                 365                 370                 375

 Pro Ala Asp Asn Pro Gly Leu Val Gln Ala Gln Pro Arg Val Pro
                 380                 385                 390

 Leu Thr Pro Thr Arg Gly Thr Ser Ser Arg Val Ala Val Gln Arg
                 395                 400                 405

 Gly Val Gly Ser Gly Pro His Pro Pro Asp Thr Gln Gln Pro Ser
                 410                 415                 420

 Pro Ser Lys Ala Phe Lys Pro Arg Phe Pro Gly Asp Gln Val Val
                 425                 430                 435

 Asn Gly Ala Gly Pro Glu Leu Ser Thr Gly Pro Ser Pro Gly Ser
                 440                 445                 450

 Pro Thr Leu Asp Ile Asp Gln Ser Ile Glu Gln Leu Asn Arg Leu
                 455                 460                 465

 Ile Leu Glu Leu Asp Pro Thr Phe Glu Pro Ile Pro Thr His Met
                 470                 475                 480

 Asn Ala Leu Gly Ser Gln Ala Asn Gly Ser Val Ser Pro Asp Ser
                 485                 490                 495

 Val Gly Gly Gly Leu Arg Ala Ser Ser Arg Leu Pro Asp Thr Gly
                 500                 505                 510

 Glu Gly Pro Ser Arg Ala Thr Gly Arg Gln Gly Ser Ser Ala Glu
                 515                 520                 525

 Gln Pro Leu Gly Gly Arg Leu Arg Lys Leu Ser Leu Gly Gln Tyr
                 530                 535                 540

 Asp Asn Asp Ala Gly Gly Gln Leu Pro Phe Ser Lys Cys Ala Trp
                 545                 550                 555

 Gly Lys Ala Gly Val Asp Tyr Ala Pro Asn Leu Pro Pro Phe Pro
                 560                 565                 570

 Ser Pro Ala Asp Val Lys Glu Thr Met Thr Pro Gly Tyr Pro Gln
                 575                 580                 585

 Asp Leu Asp Ile Ile Asp Gly Arg Ile Leu Ser Ser Lys Glu Ser
                 590                 595                 600

 Met Cys Ser Thr Pro Ala Phe Pro Val Ser Pro Glu Thr Pro Tyr
                 605                 610                 615

 Val Lys Thr Ala Leu Arg His Pro Pro Phe Ser Pro Pro Glu Pro
                 620                 625                 630

 Pro Leu Ser Ser Pro Ala Ser Gln His Lys Gly Gly Arg Glu Pro
                 635                 640                 645

 Arg Ser Cys Pro Glu Thr Leu Thr His Ala Val Gly Met Ser Glu
                 650                 655                 660

 Ser Pro Ile Gly Pro Lys Ser Thr Met Leu Arg Ala Asp Ala Ser
                 665                 670                 675

 Ser Thr Pro Ser Phe Gln Gln Ala Phe Ala Ser Ser Cys Thr Ile
                 680                 685                 690

 Ser Ser Asn Gly Pro Gly Gln Arg Arg Glu Ser Ser Ser Ser Ala
                 695                 700                 705

 Glu Arg Gln Trp Val Glu Ser Ser Pro Lys Pro Met Val Ser Leu
                 710                 715                 720

 Leu Gly Ser Gly Arg Pro Thr Gly Ser Pro Leu Ser Ala Glu Phe
                 725                 730                 735

 Ser Gly Thr Arg Lys Asp Ser Pro Val Leu Ser Cys Phe Pro Pro
                 740                 745                 750

 Ser Glu Leu Gln Ala Pro Phe His Ser His Glu Leu Ser Leu Ala
                 755                 760                 765

 Glu Pro Pro Asp Ser Leu Ala Pro Pro Ser Ser Gln Ala Phe Leu
                 770                 775                 780

 Gly Phe Gly Thr Ala Pro Val Gly Ser Gly Leu Pro Pro Glu Glu
                 785                 790                 795

 Asp Leu Gly Ala Leu Leu Ala Asn Ser His Gly Ala Ser Pro Thr
                 800                 805                 810

 Pro Ser Ile Pro Leu Thr Ala Thr Gly Ala Ala Asp Asn Gly Phe
                 815                 820                 825

 Leu Ser His Asn Phe Leu Thr Val Ala Pro Gly His Ser Ser His
                 830                 835                 840

 His Ser Pro Gly Leu Gln Gly Gln Gly Val Thr Leu Pro Gly Gln
                 845                 850                 855

 Pro Pro Leu Pro Glu Lys Lys Arg Ala Ser Glu Gly Asp Arg Ser
                 860                 865                 870

 Leu Gly Ser Val Ser Pro Ser Ser Ser Gly Phe Ser Ser Pro His
                 875                 880                 885

 Ser Gly Ser Thr Ile Ser Ile Pro Phe Pro Asn Val Leu Pro Asp
                 890                 895                 900

 Phe Ser Lys Ala Ser Glu Ala Ala Ser Pro Leu Pro Asp Ser Pro
                 905                 910                 915

 Gly Asp Lys Leu Val Ile Val Lys Phe Val Gln Asp Thr Ser Lys
                 920                 925                 930

 Phe Trp Tyr Lys Ala Asp Ile Ser Arg Glu Gln Ala Ile Ala Met
                 935                 940                 945

 Leu Lys Asp Lys Glu Pro Gly Ser Phe Ile Val Arg Asp Ser His
                 950                 955                 960

 Ser Phe Arg Gly Ala Tyr Gly Leu Ala Met Lys Val Ala Thr Pro
                 965                 970                 975

 Pro Pro Ser Val Leu Gln Leu Asn Lys Lys Ala Gly Asp Leu Ala
                 980                 985                 990

 Asn Glu Leu Val Arg His Phe Leu Ile Glu Cys Thr Pro Lys Gly
                 995                1000                1005

 Val Arg Leu Lys Gly Cys Ser Asn Glu Pro Tyr Phe Gly Ser Leu
                1010                1015                1020

 Thr Ala Leu Val Cys Gln His Ser Ile Thr Pro Leu Ala Leu Pro
                1025                1030                1035

 Cys Lys Leu Leu Ile Pro Glu Arg Asp Pro Leu Glu Glu Ile Ala
                1040                1045                1050

 Glu Ser Ser Pro Gln Thr Ala Ala Asn Ser Ala Ala Glu Leu Leu
                1055                1060                1065

 Lys Gln Gly Ala Ala Cys Asn Val Trp Tyr Leu Asn Ser Val Glu
                1070                1075                1080

 Met Glu Ser Leu Thr Gly His Gln Ala Ile Gln Lys Ala Leu Ser
                1085                1090                1095

 Ile Thr Leu Val Gln Glu Pro Pro Pro Val Ser Thr Val Val His
                1100                1105                1110

 Phe Lys Val Ser Ala Gln Gly Ile Thr Leu Thr Asp Asn Gln Arg
                1115                1120                1125

 Lys Leu Phe Phe Arg Arg His Tyr Pro Val Asn Ser Val Ile Phe
                1130                1135                1140

 Cys Ala Leu Asp Pro Gln Asp Arg Lys Trp Ile Lys Asp Gly Pro
                1145                1150                1155

 Ser Ser Lys Val Phe Gly Phe Val Ala Arg Lys Gln Gly Ser Ala
                1160                1165                1170

 Thr Asp Asn Val Cys His Leu Phe Ala Glu His Asp Pro Glu Gln
                1175                1180                1185

 Pro Ala Ser Ala Ile Val Asn Phe Val Ser Lys Val Met Ile Gly
                1190                1195                1200

 Ser Pro Lys Lys Val
                1205

<210> 3090
<211> 1238
<212> DNA
<213> Homo sapien

<400> 3090
 ggcggcggcg gcggaggctg ccatggacga cgaggaggag acgtaccggc 50

 tctggaaaat ccgcaagacc atcatgcagc tgtgccacga ccgtggctat 100

 ctggtgaccc aggacgagct tgaccagacc ctggaggagt tcaaagccca 150

 atttggggac aagccgagtg aggggcggcc gcggcgcacg gacctcaccg 200

 tgctggtggc ccacaacgat gaccccaccg accagatgtt tgtgttcttt 250

 ccagaggagc ccaaggtggg catcaagacc atcaaggtgt actgccagcg 300

 catgcaggag gagaacatca cacgggctct catcgtggtg cagcagggca 350

 tgacaccctc cgccaagcag tccctggtcg acatggcccc caagtacatc 400

 ctggagcagt ttctgcagca ggagctgctc atcaacatca cggagcacga 450

 gctagtccct gagcacgtcg tcatgaccaa ggaggaggtg acagagctgc 500

 tggcccgata taagctccga gagaaccagc tgcccaggat ccaggcgggg 550

 gaccctgtgg cgcgctactt tgggataaag cgtgggcagg tggtgaagat 600

 catccggccc agtgagacgg ctggcaggta catcacctac cggctggtgc 650

 agtagctacc gcctgacagc ccctagaggc ggacacacag cgacccccat 700

 ccctgcagga caaacgcccc tgccctgcca gaatccggcc cccacagctc 750

 tcacggctgc tgctcctctg gactccccaa ggcaggtggc ctccacccac 800

 gttctcccgt cctggggtga ggcttcctgt ggcccagccc gccccattca 850

 cctgtggatt tgtgcgagat gcagcctcag aaggaacaag gcccccagag 900

 ggaggtcacc tgggggcagc tggtgccggg tcttcaccca gaccacgctg 950

 ggtcccctct gttgggggtt tggggtccgg gtctcccacc agccactgct 1000

 tcctcctggg ccctcggctt ccacccctcg tcttccctcc ctcggggccc 1050

 tgatgcgtgg cggcccccac ccggcctcgg ctctttactc cattcacagc 1100

 catgcacgcg ctcaagtaca ccagggtgcg agatgccagc tctggagttc 1150

 tcggttgttg taggaggttg ggtgttttca aatggtaaag atgttttgac 1200

 gaaataaatt tgcttgatac agaaaaaaaa aaaaaaaa 1238

<210> 3091
<211> 210
<212> PRT
<213> Homo sapien

<400> 3091
 Met Asp Asp Glu Glu Glu Thr Tyr Arg Leu Trp Lys Ile Arg Lys
   1               5                  10                  15

 Thr Ile Met Gln Leu Cys His Asp Arg Gly Tyr Leu Val Thr Gln
                  20                  25                  30

 Asp Glu Leu Asp Gln Thr Leu Glu Glu Phe Lys Ala Gln Phe Gly
                  35                  40                  45

 Asp Lys Pro Ser Glu Gly Arg Pro Arg Arg Thr Asp Leu Thr Val
                  50                  55                  60

 Leu Val Ala His Asn Asp Asp Pro Thr Asp Gln Met Phe Val Phe
                  65                  70                  75

 Phe Pro Glu Glu Pro Lys Val Gly Ile Lys Thr Ile Lys Val Tyr
                  80                  85                  90

 Cys Gln Arg Met Gln Glu Glu Asn Ile Thr Arg Ala Leu Ile Val
                  95                 100                 105

 Val Gln Gln Gly Met Thr Pro Ser Ala Lys Gln Ser Leu Val Asp
                 110                 115                 120

 Met Ala Pro Lys Tyr Ile Leu Glu Gln Phe Leu Gln Gln Glu Leu
                 125                 130                 135

 Leu Ile Asn Ile Thr Glu His Glu Leu Val Pro Glu His Val Val
                 140                 145                 150

 Met Thr Lys Glu Glu Val Thr Glu Leu Leu Ala Arg Tyr Lys Leu
                 155                 160                 165

 Arg Glu Asn Gln Leu Pro Arg Ile Gln Ala Gly Asp Pro Val Ala
                 170                 175                 180

 Arg Tyr Phe Gly Ile Lys Arg Gly Gln Val Val Lys Ile Ile Arg
                 185                 190                 195

 Pro Ser Glu Thr Ala Gly Arg Tyr Ile Thr Tyr Arg Leu Val Gln
                 200                 205                 210

<210> 3092
<211> 1862
<212> DNA
<213> Homo sapien

<400> 3092
 ggactttgtg ttccgctgac cctcctcggg gcgcttcctc ccgtgccgcc 50

 cttcccctcc cccgccgcgt ccttgcgagg cgcctcccat tcggtgggac 100

 cgacccgggg ggatggaggg ggcacgcttc tacaaccctc ctgggacccc 150

 gaagagacgc ccgcgtgcga cctgagacgc cgccctcgcc gagggcccat 200

 gggcgcgtcc ccacaggcgg gcagtggacg tgagggcggc gagcggcggg 250

 gccgcggcgt ccaggagggc cgcgctcggg ctcggcccgc gcaggccgcg 300

 cgcgcgcgct cccgccgccg cccgggccgc gcccgccccg cctctaggcg 350

 ccggccccgg agcccggtcc gcgagcagcg gcggctgccg gagggacgat 400

 gagctgcgcg gggcgggcgg gccctgcccg gctcgccgcg ctcgccctgc 450

 tgacctgcag cctgtggccg gcacgggcag acaacgcgag ccaggagtac 500

 tacacggcgc tcatcaacgt gacggtgcag gagcccggcc gcggcgcccc 550

 gctcacgttt cgcatcgacc gcgggcgcta cgggcttgac tcccccaagg 600

 ccgaggtccg cggccaggtg ctggcgccgc tgcccctcca cggagttgct 650

 gatcatctgg gctgtgatcc acaaacccgg ttctttgtcc ctcctaatat 700

 caaacagtgg attgccttgc tgcagagggg aaactgcacg tttaaagaga 750

 aaatatcacg ggccgctttc cacaatgcag ttgctgtagt catctacaat 800

 aataaatcca aagaggagcc agttaccatg actcatccag gcactggaga 850

 tattattgct gtcatgataa cagaattgag gggtaaggat attttgagtt 900

 atctggagaa aaacatctct gtacaaatga caatagctgt tggaactcga 950

 atgccaccga agaacttcag ccgtggctct ctagtcttcg tgtcaatatc 1000

 ctttattgtt ttgatgatta tttcttcagc atggctcata ttctacttca 1050

 ttcagaagat caggtacaca aatgcacgcg acaggaacca gcgtcgtctc 1100

 ggagatgcag ccaagaaagc catcagtaaa ttgacaacca ggacagtaaa 1150

 gaagggtgac aaggaaactg acccagactt tgatcattgt gcagtctgca 1200

 tagagagcta taagcagaat gatgtcgtcc gaattctccc ctgcaagcat 1250

 gttttccaca aatcctgcgt ggatccctgg cttagtgaac attgtacctg 1300

 tcctatgtgc aaacttaata tattgaaggc cctgggaatt gtgccgaatt 1350

 tgccatgtac tgataacgta gcattcgata tggaaaggct caccagaacc 1400

 caagctgtta accgaagatc agccctcggc gacctcgccg gcgacaactc 1450

 ccttggcctt gagccacttc gaacttcggg gatctcacct cttcctcagg 1500

 atggggagct cactccgaga acaggagaaa tcaacattgc agtaacaaaa 1550

 gaatggttta ttattgccag ttttggcctc ctcagtgccc tcacactctg 1600

 ctacatgatc atcagagcca cagctagctt gaatgctaat gaggtagaat 1650

 ggttttgaag aagaaaaaac ctgctttctg actgattttg ccttgaagga 1700

 aaaaagaacc tatttttgtg catcatttac caatcatgcc acacaagcat 1750

 ttatttttag tacattttat tttttcataa aattgctaat gccaaagctt 1800

 tgtattaaaa gaaataaata ataaaataaa aaaaaaaaaa aaaaaaaaaa 1850

 aaaaaaaaaa aa 1862

<210> 3093
<211> 419
<212> PRT
<213> Homo sapien

<400> 3093
 Met Ser Cys Ala Gly Arg Ala Gly Pro Ala Arg Leu Ala Ala Leu
   1               5                  10                  15

 Ala Leu Leu Thr Cys Ser Leu Trp Pro Ala Arg Ala Asp Asn Ala
                  20                  25                  30

 Ser Gln Glu Tyr Tyr Thr Ala Leu Ile Asn Val Thr Val Gln Glu
                  35                  40                  45

 Pro Gly Arg Gly Ala Pro Leu Thr Phe Arg Ile Asp Arg Gly Arg
                  50                  55                  60

 Tyr Gly Leu Asp Ser Pro Lys Ala Glu Val Arg Gly Gln Val Leu
                  65                  70                  75

 Ala Pro Leu Pro Leu His Gly Val Ala Asp His Leu Gly Cys Asp
                  80                  85                  90

 Pro Gln Thr Arg Phe Phe Val Pro Pro Asn Ile Lys Gln Trp Ile
                  95                 100                 105

 Ala Leu Leu Gln Arg Gly Asn Cys Thr Phe Lys Glu Lys Ile Ser
                 110                 115                 120

 Arg Ala Ala Phe His Asn Ala Val Ala Val Val Ile Tyr Asn Asn
                 125                 130                 135

 Lys Ser Lys Glu Glu Pro Val Thr Met Thr His Pro Gly Thr Gly
                 140                 145                 150

 Asp Ile Ile Ala Val Met Ile Thr Glu Leu Arg Gly Lys Asp Ile
                 155                 160                 165

 Leu Ser Tyr Leu Glu Lys Asn Ile Ser Val Gln Met Thr Ile Ala
                 170                 175                 180

 Val Gly Thr Arg Met Pro Pro Lys Asn Phe Ser Arg Gly Ser Leu
                 185                 190                 195

 Val Phe Val Ser Ile Ser Phe Ile Val Leu Met Ile Ile Ser Ser
                 200                 205                 210

 Ala Trp Leu Ile Phe Tyr Phe Ile Gln Lys Ile Arg Tyr Thr Asn
                 215                 220                 225

 Ala Arg Asp Arg Asn Gln Arg Arg Leu Gly Asp Ala Ala Lys Lys
                 230                 235                 240

 Ala Ile Ser Lys Leu Thr Thr Arg Thr Val Lys Lys Gly Asp Lys
                 245                 250                 255

 Glu Thr Asp Pro Asp Phe Asp His Cys Ala Val Cys Ile Glu Ser
                 260                 265                 270

 Tyr Lys Gln Asn Asp Val Val Arg Ile Leu Pro Cys Lys His Val
                 275                 280                 285

 Phe His Lys Ser Cys Val Asp Pro Trp Leu Ser Glu His Cys Thr
                 290                 295                 300

 Cys Pro Met Cys Lys Leu Asn Ile Leu Lys Ala Leu Gly Ile Val
                 305                 310                 315

 Pro Asn Leu Pro Cys Thr Asp Asn Val Ala Phe Asp Met Glu Arg
                 320                 325                 330

 Leu Thr Arg Thr Gln Ala Val Asn Arg Arg Ser Ala Leu Gly Asp
                 335                 340                 345

 Leu Ala Gly Asp Asn Ser Leu Gly Leu Glu Pro Leu Arg Thr Ser
                 350                 355                 360

 Gly Ile Ser Pro Leu Pro Gln Asp Gly Glu Leu Thr Pro Arg Thr
                 365                 370                 375

 Gly Glu Ile Asn Ile Ala Val Thr Lys Glu Trp Phe Ile Ile Ala
                 380                 385                 390

 Ser Phe Gly Leu Leu Ser Ala Leu Thr Leu Cys Tyr Met Ile Ile
                 395                 400                 405

 Arg Ala Thr Ala Ser Leu Asn Ala Asn Glu Val Glu Trp Phe
                 410                 415

<210> 3094
<211> 2993
<212> DNA
<213> Homo sapien

<400> 3094
 cgctggggcg ctttccgagg aaattcggga ctcgagtttc ccggggaaga 50

 ggcgcggcct gagcccggcg agggtgggga gggcaggcgc aggtggaccc 100

 cggcgccccc cgagccccgc tgtgaccttg gccgcggggg aggggctggg 150

 ccgctgcggg gcagtcgcgg ccgccagagg gggcagcgga gaagaacttg 200

 cccaacttgg cggcgcgggc tggggcggct ctgcgcctcc gcgcccgcct 250

 ccccggcctc cgccttctcc cctcccgcga gcctcctccc ctcccgcgag 300

 cctcctcccc tgggccctcc tcccgtcctc cccgccgccg ccggtcccgg 350

 tgcgcgccca tccctgcccg cagccccgcg cgccggccga gtcgctgagc 400

 cgcggctgcc ggacgggacg ggaccggcta ggctgggcgc gccccccggg 450

 ccccgccgtg ggcatgggcg cactggcccg ggcgctgctg ctgcctctgc 500

 tggcccagtg gctcctgcgc gccgccccgg agctggcccc cgcgcccttc 550

 acgctgcccc tccgggtggc cgcggccacg aaccgcgtag ttgcgcccac 600

 cccgggaccc gggacccctg ccgagcgcca cgccgacggc ttggcgctcg 650

 ccctggagcc tgccctggcg tcccccgcgg gcgccgccaa cttcttggcc 700

 atggtagaca acctgcaggg ggactctggc cgcggctact acctggagat 750

 gctgatcggg acccccccgc agaagctaca gattctcgtt gacactggaa 800

 gcagtaactt tgccgtggca ggaaccccgc actcctacat agacacgtac 850

 tttgacacag agaggtctag cacataccgc tccaagggct ttgacgtcac 900

 agtgaagtac acacaaggaa gctggacggg cttcgttggg gaagacctcg 950

 tcaccatccc caaaggcttc aatacttctt ttcttgtcaa cattgccact 1000

 atttttgaat cagagaattt ctttttgcct gggattaaat ggaatggaat 1050

 acttggccta gcttatgcca cacttgccaa gccatcaagt tctctggaga 1100

 ccttcttcga ctccctggtg acacaagcaa acatccccaa cgttttctcc 1150

 atgcagatgt gtggagccgg cttgcccgtt gctggatctg ggaccaacgg 1200

 aggtagtctt gtcttgggtg gaattgaacc aagtttgtat aaaggagaca 1250

 tctggtatac ccctattaag gaagagtggt actaccagat agaaattctg 1300

 aaattggaaa ttggaggcca aagccttaat ctggactgca gagagtataa 1350

 cgcagacaag gccatcgtgg acagtggcac cacgctgctg cgcctgcccc 1400

 agaaggtgtt tgatgcggtg gtggaagctg tggcccgcgc atctctgatt 1450

 ccagaattct ctgatggttt ctggactggg tcccagctgg cgtgctggac 1500

 gaattcggaa acaccttggt cttacttccc taaaatctcc atctacctga 1550

 gagacgagaa ctccagcagg tcattccgta tcacaatcct gcctcagctt 1600

 tacattcagc ccatgatggg ggccggcctg aattatgaat gttaccgatt 1650

 cggcatttcc ccatccacaa atgcgctggt gatcggtgcc acggtgatgg 1700

 agggcttcta cgtcatcttc gacagagccc agaagagggt gggcttcgca 1750

 gcgagcccct gtgcagaaat tgcaggtgct gcagtgtctg aaatttccgg 1800

 gcctttctca acagaggatg tagccagcaa ctgtgtcccc gctcagtctt 1850

 tgagcgagcc cattttgtgg attgtgtcct atgcgctcat gagcgtctgt 1900

 ggagccatcc tccttgtctt aatcgtcctg ctgctgctgc cgttccggtg 1950

 tcagcgtcgc ccccgtgacc ctgaggtcgt caatgatgag tcctctctgg 2000

 tcagacatcg ctggaaatga atagccaggc ctgacctcaa gcaaccatga 2050

 actcagctat taagaaaatc acatttccag ggcagcagcc gggatcgatg 2100

 gtggcgcttt ctcctgtgcc cacccgtctt caatctctgt tctgctccca 2150

 gatgccttct agattcactg tcttttgatt cttgattttc aagctttcaa 2200

 atcctcccta cttccaagaa aaataattaa aaaaaaaact tcattctaaa 2250

 ccaaaacaga gtggattggg ctgcaggctc tatggggttc gttatgccaa 2300

 agtgtctaca tgtgccacca acataaaaca aaaccaagcc ttggctcgtt 2350

 ctcttctctc ttcaatctct ggaaaaataa gtacatatag ttgataaccc 2400

 ctcttagctt acaggaagct ttttgtatta attgcctttg aggttatttt 2450

 ccgccagacc tcaacctggg tcaaagtggt acaggaaggc ttgcagtatg 2500

 atggcaggag aatcagcctg gggcctgggg atgtaaccaa gctgtaccct 2550

 tgagacctgg aaccagagcc acaggcccct tttgtgggtt tctctgtgct 2600

 ctgaatggga gccagaattc actaggaggt catcaaccga tggtcctcac 2650

 aagcctcttc tgaagatgga aggccttttg cccgttgagg tagaggggaa 2700

 ggaaatctcc tcttttgtac ccaatactta tgttgtattg ttggtgcgaa 2750

 agtaaaaaca ctacctcttt tgagactttg cccagggtcc tgtgcctgga 2800

 tgggggtgca ggcagccttg accacggctg ttcccctcac ccaaaagaat 2850

 tatcatccca acagccaaga cccaacaggt gctgaactgt gcatcaacca 2900

 ggaagagttc tatccccaag ctggccacta tcacatatgc ttactcttgc 2950

 ttaaaattaa taaatcatgt tttgatgaga aaaaactatt cta 2993

<210> 3095
<211> 518
<212> PRT
<213> Homo sapien

<400> 3095
 Met Gly Ala Leu Ala Arg Ala Leu Leu Leu Pro Leu Leu Ala Gln
   1               5                  10                  15

 Trp Leu Leu Arg Ala Ala Pro Glu Leu Ala Pro Ala Pro Phe Thr
                  20                  25                  30

 Leu Pro Leu Arg Val Ala Ala Ala Thr Asn Arg Val Val Ala Pro
                  35                  40                  45

 Thr Pro Gly Pro Gly Thr Pro Ala Glu Arg His Ala Asp Gly Leu
                  50                  55                  60

 Ala Leu Ala Leu Glu Pro Ala Leu Ala Ser Pro Ala Gly Ala Ala
                  65                  70                  75

 Asn Phe Leu Ala Met Val Asp Asn Leu Gln Gly Asp Ser Gly Arg
                  80                  85                  90

 Gly Tyr Tyr Leu Glu Met Leu Ile Gly Thr Pro Pro Gln Lys Leu
                  95                 100                 105

 Gln Ile Leu Val Asp Thr Gly Ser Ser Asn Phe Ala Val Ala Gly
                 110                 115                 120

 Thr Pro His Ser Tyr Ile Asp Thr Tyr Phe Asp Thr Glu Arg Ser
                 125                 130                 135

 Ser Thr Tyr Arg Ser Lys Gly Phe Asp Val Thr Val Lys Tyr Thr
                 140                 145                 150

 Gln Gly Ser Trp Thr Gly Phe Val Gly Glu Asp Leu Val Thr Ile
                 155                 160                 165

 Pro Lys Gly Phe Asn Thr Ser Phe Leu Val Asn Ile Ala Thr Ile
                 170                 175                 180

 Phe Glu Ser Glu Asn Phe Phe Leu Pro Gly Ile Lys Trp Asn Gly
                 185                 190                 195

 Ile Leu Gly Leu Ala Tyr Ala Thr Leu Ala Lys Pro Ser Ser Ser
                 200                 205                 210

 Leu Glu Thr Phe Phe Asp Ser Leu Val Thr Gln Ala Asn Ile Pro
                 215                 220                 225

 Asn Val Phe Ser Met Gln Met Cys Gly Ala Gly Leu Pro Val Ala
                 230                 235                 240

 Gly Ser Gly Thr Asn Gly Gly Ser Leu Val Leu Gly Gly Ile Glu
                 245                 250                 255

 Pro Ser Leu Tyr Lys Gly Asp Ile Trp Tyr Thr Pro Ile Lys Glu
                 260                 265                 270

 Glu Trp Tyr Tyr Gln Ile Glu Ile Leu Lys Leu Glu Ile Gly Gly
                 275                 280                 285

 Gln Ser Leu Asn Leu Asp Cys Arg Glu Tyr Asn Ala Asp Lys Ala
                 290                 295                 300

 Ile Val Asp Ser Gly Thr Thr Leu Leu Arg Leu Pro Gln Lys Val
                 305                 310                 315

 Phe Asp Ala Val Val Glu Ala Val Ala Arg Ala Ser Leu Ile Pro
                 320                 325                 330

 Glu Phe Ser Asp Gly Phe Trp Thr Gly Ser Gln Leu Ala Cys Trp
                 335                 340                 345

 Thr Asn Ser Glu Thr Pro Trp Ser Tyr Phe Pro Lys Ile Ser Ile
                 350                 355                 360

 Tyr Leu Arg Asp Glu Asn Ser Ser Arg Ser Phe Arg Ile Thr Ile
                 365                 370                 375

 Leu Pro Gln Leu Tyr Ile Gln Pro Met Met Gly Ala Gly Leu Asn
                 380                 385                 390

 Tyr Glu Cys Tyr Arg Phe Gly Ile Ser Pro Ser Thr Asn Ala Leu
                 395                 400                 405

 Val Ile Gly Ala Thr Val Met Glu Gly Phe Tyr Val Ile Phe Asp
                 410                 415                 420

 Arg Ala Gln Lys Arg Val Gly Phe Ala Ala Ser Pro Cys Ala Glu
                 425                 430                 435

 Ile Ala Gly Ala Ala Val Ser Glu Ile Ser Gly Pro Phe Ser Thr
                 440                 445                 450

 Glu Asp Val Ala Ser Asn Cys Val Pro Ala Gln Ser Leu Ser Glu
                 455                 460                 465

 Pro Ile Leu Trp Ile Val Ser Tyr Ala Leu Met Ser Val Cys Gly
                 470                 475                 480

 Ala Ile Leu Leu Val Leu Ile Val Leu Leu Leu Leu Pro Phe Arg
                 485                 490                 495

 Cys Gln Arg Arg Pro Arg Asp Pro Glu Val Val Asn Asp Glu Ser
                 500                 505                 510

 Ser Leu Val Arg His Arg Trp Lys
                 515

<210> 3096
<211> 3277
<212> DNA
<213> Homo sapien

<400> 3096
 aatcgctcgg cctcccccat cccccgggta acggtcgctg gtgagtttaa 50

 atgagcaggg gctggccggg ccggagccgc tacagggggg gcctgaggca 100

 ctgcagaaag tgggcctgag cctcgaggat gacggtgctg caggaacccg 150

 tccaggctgc tatatggcaa gcactaaacc actatgctta ccgagatgcg 200

 gttttcctcg cagaacgcct ttatgcagaa gtacactcag aagaagcctt 250

 gtttttactg gcaacctgtt attaccgctc aggaaaggca tataaagcat 300

 atagactctt gaaaggacac agttgtacta caccgcaatg caaatacctg 350

 cttgcaaaat gttgtgttga tctcagcaag cttgcagaag gggaacaaat 400

 cttatctggt ggagtgttta ataagcagaa aagccatgat gatattgtta 450

 ctgagtttgg tgattcagct tgctttactc tttcattgtt gggacatgta 500

 tattgcaaga cagatcggct tgccaaagga tcagaatgtt accaaaagag 550

 ccttagttta aatcctttcc tctggtctcc ctttgaatca ttatgtgaaa 600

 taggtgaaaa gccagatcct gaccaaacat ttaaattcac atctttacag 650

 aactttagca actgtctgcc caactcttgc acaacacaag tacctaatca 700

 tagtttatct cacagacagc ctgagacagt tcttacggaa acaccccagg 750

 acacaattga attaaacaga ttgaatttag aatcttccaa ttcaaagtac 800

 tccttgaata cagattcctc agtgtcttat attgattcag ctgtaatttc 850

 acctgatact gtcccactgg gaacaggaac ttccatatta tctaaacagg 900

 ttcaaaataa accaaaaact ggtcgaagtt tattaggagg accagcagct 950

 cttagtccat taaccccaag ttttgggatt ttgccattag aaaccccaag 1000

 tcctggagat ggatcctatt tacaaaacta cactaataca cctcctgtaa 1050

 ttgatgtgcc atccaccgga gccccttcaa aaaagtctgt tgccagaatc 1100

 ggccaaactg gaacaaagtc tgtcttctca cagagtggaa atagccgaga 1150

 ggtaactcca attcttgcac aaacacaaag ttctggtcca caaacaagta 1200

 caacacctca ggtattgagc cccactatta catctccccc aaacgcactg 1250

 cctcgaagaa gttcacgact ctttactagt gacagctcca caaccaagga 1300

 gaatagcaaa aaattaaaaa tgaagtttcc acctaaaatc ccaaacagaa 1350

 aaacaaaaag taaaactaat aaaggaggaa taactcaacc taacataaat 1400

 gatagcctgg aaattacaaa attggactct tccatcattt cagaagggaa 1450

 aatatccaca atcacacctc agattcaggc ctttaatcta caaaaagcag 1500

 cagcagcagg tttgatgagc cttcttcgtg aaatggggaa aggttattta 1550

 gctttgtgtt catacaactg caaagaagct ataaatattt tgagccatct 1600

 accttctcac cactacaata ctggttgggt actgtgccaa attggaaggg 1650

 cctattttga actttcagag tacatgcaag ctgaaagaat attctcagag 1700

 gttagaagga ttgagaatta tagagttgaa ggcatggaga tctactctac 1750

 aacactttgg catcttcaaa aagatgttgc tctttcagtt ctgtcaaaag 1800

 acttaacaga catggataaa aattcgccag aggcctggtg tgctgcaggg 1850

 aactgtttca gtctgcaacg ggaacatgat attgcaatta aattcttcca 1900

 gagagctatc caagttgatc caaattacgc ttatgcctat actctattag 1950

 ggcatgagtt tgtcttaact gaagaattgg acaaagcatt agcttgtttt 2000

 cgaaatgcta tcagagtcaa tcctagacat tataatgcat ggtatggttt 2050

 aggaatgatt tattacaagc aagaaaaatt cagccttgca gaaatgcatt 2100

 tccaaaaagc gcttgatatc aaccctcaaa gttcagtttt actttgccac 2150

 attggagtag ttcaacatgc actgaaaaaa tcagagaagg ctttggatac 2200

 cctaaacaaa gccattgtca ttgatcccaa gaaccctcta tgcaaatttc 2250

 acagagcctc agttttattt gcaaatgaaa aatataagtc tgctttacaa 2300

 gaacttgaag aattgaaaca aattgttccc aaagaatccc tcgtttactt 2350

 cttaatagga aaggtttaca agaagttagg tcaaacgcac ctcgccctga 2400

 tgaatttctc ttgggctatg gatttagatc ctaaaggagc caataaccag 2450

 attaaagagg caattgataa gcgttatctt ccagatgatg aggagccaat 2500

 aacccaagaa gaacagatca tgggaacaga tgaatcccag gagagcagca 2550

 tgacagatgc ggatgacaca caacttcatg cagctgaaag tgatgaattt 2600

 taacttctgg aaatcagact tttacaactg gatgtgtgac tagtgctgac 2650

 gtgtttcttg tccctctgta tactgagtct ttactcttga gctggcggtg 2700

 tcatcgtccg tcacttatac catgagtgtg ccactttcat tggaccctga 2750

 ctgtatacag aatgaaaggc agtgcaatat ttagctgcta acaagactgg 2800

 ctcttttacc agtatgaatg acaatttatg gggggtaggg tggggaactt 2850

 tcttttctgt ttttctttaa tctccctttg ttggaaagta tcatgaagga 2900

 agagttatgc tttatcttga aggaaccatt agatatggaa aatagtgatg 2950

 aaccagagtt tcttggttgc tttttcaaaa atttgttttt atttggttct 3000

 gttccagata aacagagtaa ctgaccttca tttctaggtt cttcaagaat 3050

 ggtgtttgca agtgccagat ggaacaataa aagacgttgc ctataacagt 3100

 gacttgattg ccaaggaatg taaattacct taaacttcga tgatctccca 3150

 taaacaaatg taatgggcat attgggactc gtatgtagga atcaaatatc 3200

 cctccataca gtgtactctt attcttggca agaatgcttt aatgtataac 3250

 caagaatttt aatttattca tcttgct 3277

<210> 3097
<211> 824
<212> PRT
<213> Homo sapien

<400> 3097
 Met Thr Val Leu Gln Glu Pro Val Gln Ala Ala Ile Trp Gln Ala
   1               5                  10                  15

 Leu Asn His Tyr Ala Tyr Arg Asp Ala Val Phe Leu Ala Glu Arg
                  20                  25                  30

 Leu Tyr Ala Glu Val His Ser Glu Glu Ala Leu Phe Leu Leu Ala
                  35                  40                  45

 Thr Cys Tyr Tyr Arg Ser Gly Lys Ala Tyr Lys Ala Tyr Arg Leu
                  50                  55                  60

 Leu Lys Gly His Ser Cys Thr Thr Pro Gln Cys Lys Tyr Leu Leu
                  65                  70                  75

 Ala Lys Cys Cys Val Asp Leu Ser Lys Leu Ala Glu Gly Glu Gln
                  80                  85                  90

 Ile Leu Ser Gly Gly Val Phe Asn Lys Gln Lys Ser His Asp Asp
                  95                 100                 105

 Ile Val Thr Glu Phe Gly Asp Ser Ala Cys Phe Thr Leu Ser Leu
                 110                 115                 120

 Leu Gly His Val Tyr Cys Lys Thr Asp Arg Leu Ala Lys Gly Ser
                 125                 130                 135

 Glu Cys Tyr Gln Lys Ser Leu Ser Leu Asn Pro Phe Leu Trp Ser
                 140                 145                 150

 Pro Phe Glu Ser Leu Cys Glu Ile Gly Glu Lys Pro Asp Pro Asp
                 155                 160                 165

 Gln Thr Phe Lys Phe Thr Ser Leu Gln Asn Phe Ser Asn Cys Leu
                 170                 175                 180

 Pro Asn Ser Cys Thr Thr Gln Val Pro Asn His Ser Leu Ser His
                 185                 190                 195

 Arg Gln Pro Glu Thr Val Leu Thr Glu Thr Pro Gln Asp Thr Ile
                 200                 205                 210

 Glu Leu Asn Arg Leu Asn Leu Glu Ser Ser Asn Ser Lys Tyr Ser
                 215                 220                 225

 Leu Asn Thr Asp Ser Ser Val Ser Tyr Ile Asp Ser Ala Val Ile
                 230                 235                 240

 Ser Pro Asp Thr Val Pro Leu Gly Thr Gly Thr Ser Ile Leu Ser
                 245                 250                 255

 Lys Gln Val Gln Asn Lys Pro Lys Thr Gly Arg Ser Leu Leu Gly
                 260                 265                 270

 Gly Pro Ala Ala Leu Ser Pro Leu Thr Pro Ser Phe Gly Ile Leu
                 275                 280                 285

 Pro Leu Glu Thr Pro Ser Pro Gly Asp Gly Ser Tyr Leu Gln Asn
                 290                 295                 300

 Tyr Thr Asn Thr Pro Pro Val Ile Asp Val Pro Ser Thr Gly Ala
                 305                 310                 315

 Pro Ser Lys Lys Ser Val Ala Arg Ile Gly Gln Thr Gly Thr Lys
                 320                 325                 330

 Ser Val Phe Ser Gln Ser Gly Asn Ser Arg Glu Val Thr Pro Ile
                 335                 340                 345

 Leu Ala Gln Thr Gln Ser Ser Gly Pro Gln Thr Ser Thr Thr Pro
                 350                 355                 360

 Gln Val Leu Ser Pro Thr Ile Thr Ser Pro Pro Asn Ala Leu Pro
                 365                 370                 375

 Arg Arg Ser Ser Arg Leu Phe Thr Ser Asp Ser Ser Thr Thr Lys
                 380                 385                 390

 Glu Asn Ser Lys Lys Leu Lys Met Lys Phe Pro Pro Lys Ile Pro
                 395                 400                 405

 Asn Arg Lys Thr Lys Ser Lys Thr Asn Lys Gly Gly Ile Thr Gln
                 410                 415                 420

 Pro Asn Ile Asn Asp Ser Leu Glu Ile Thr Lys Leu Asp Ser Ser
                 425                 430                 435

 Ile Ile Ser Glu Gly Lys Ile Ser Thr Ile Thr Pro Gln Ile Gln
                 440                 445                 450

 Ala Phe Asn Leu Gln Lys Ala Ala Ala Ala Gly Leu Met Ser Leu
                 455                 460                 465

 Leu Arg Glu Met Gly Lys Gly Tyr Leu Ala Leu Cys Ser Tyr Asn
                 470                 475                 480

 Cys Lys Glu Ala Ile Asn Ile Leu Ser His Leu Pro Ser His His
                 485                 490                 495

 Tyr Asn Thr Gly Trp Val Leu Cys Gln Ile Gly Arg Ala Tyr Phe
                 500                 505                 510

 Glu Leu Ser Glu Tyr Met Gln Ala Glu Arg Ile Phe Ser Glu Val
                 515                 520                 525

 Arg Arg Ile Glu Asn Tyr Arg Val Glu Gly Met Glu Ile Tyr Ser
                 530                 535                 540

 Thr Thr Leu Trp His Leu Gln Lys Asp Val Ala Leu Ser Val Leu
                 545                 550                 555

 Ser Lys Asp Leu Thr Asp Met Asp Lys Asn Ser Pro Glu Ala Trp
                 560                 565                 570

 Cys Ala Ala Gly Asn Cys Phe Ser Leu Gln Arg Glu His Asp Ile
                 575                 580                 585

 Ala Ile Lys Phe Phe Gln Arg Ala Ile Gln Val Asp Pro Asn Tyr
                 590                 595                 600

 Ala Tyr Ala Tyr Thr Leu Leu Gly His Glu Phe Val Leu Thr Glu
                 605                 610                 615

 Glu Leu Asp Lys Ala Leu Ala Cys Phe Arg Asn Ala Ile Arg Val
                 620                 625                 630

 Asn Pro Arg His Tyr Asn Ala Trp Tyr Gly Leu Gly Met Ile Tyr
                 635                 640                 645

 Tyr Lys Gln Glu Lys Phe Ser Leu Ala Glu Met His Phe Gln Lys
                 650                 655                 660

 Ala Leu Asp Ile Asn Pro Gln Ser Ser Val Leu Leu Cys His Ile
                 665                 670                 675

 Gly Val Val Gln His Ala Leu Lys Lys Ser Glu Lys Ala Leu Asp
                 680                 685                 690

 Thr Leu Asn Lys Ala Ile Val Ile Asp Pro Lys Asn Pro Leu Cys
                 695                 700                 705

 Lys Phe His Arg Ala Ser Val Leu Phe Ala Asn Glu Lys Tyr Lys
                 710                 715                 720

 Ser Ala Leu Gln Glu Leu Glu Glu Leu Lys Gln Ile Val Pro Lys
                 725                 730                 735

 Glu Ser Leu Val Tyr Phe Leu Ile Gly Lys Val Tyr Lys Lys Leu
                 740                 745                 750

 Gly Gln Thr His Leu Ala Leu Met Asn Phe Ser Trp Ala Met Asp
                 755                 760                 765

 Leu Asp Pro Lys Gly Ala Asn Asn Gln Ile Lys Glu Ala Ile Asp
                 770                 775                 780

 Lys Arg Tyr Leu Pro Asp Asp Glu Glu Pro Ile Thr Gln Glu Glu
                 785                 790                 795

 Gln Ile Met Gly Thr Asp Glu Ser Gln Glu Ser Ser Met Thr Asp
                 800                 805                 810

 Ala Asp Asp Thr Gln Leu His Ala Ala Glu Ser Asp Glu Phe
                 815                 820

<210> 3098
<211> 1109
<212> DNA
<213> Homo sapien

<400> 3098
 actggaagac caggcagccc agctgaaggc agtaagctcg gctcacagtc 50

 gcaggagagt tctggggtac acgggcaaag gggcttgaga aggcccggag 100

 gcgaagccga agagaagcaa ctgtgccccg gagaagagaa gctcgcccat 150

 tccagactgg gaaccagctt tcagtgaaga tggcagggcc agaactgttg 200

 ctcgactcca acatccgcct ctgggtggtc ctacccatcg ttatcatcac 250

 tttcttcgta ggcatgatcc gccactacgt gtccatcctg ctgcagagcg 300

 acaagaagct cacccaggaa caagtatctg acagtcaagt cctaattcga 350

 agcagagtcc tcagggaaaa tggaaaatac attcccaaac agtctttctt 400

 gacacgaaaa tattatttca acaacccaga ggatggattt ttcaaaaaaa 450

 ctaaacggaa ggtagtgcca ccttctccta tgactgatcc tactatgttg 500

 acagacatga tgaaagggaa tgtaacaaat gtcctcccta tgattcttat 550

 tggtggatgg atcaacatga cattctcagg ctttgtcaca accaaggtcc 600

 catttccact gaccctccgt tttaagccta tgttacagca aggaatcgag 650

 ctactcacat tagatgcatc ctgggtgagt tctgcatcct ggtacttcct 700

 caatgtattt gggcttcgga gcatttactc tctgattctg ggccaagata 750

 atgccgctga ccaatcacga atgatgcagg agcagatgac gggagcagcc 800

 atggccatgc ccgcagacac aaacaaagct ttcaagacag agtgggaagc 850

 tttggagctg acggatcacc agtgggcact agatgatgtc gaagaagagc 900

 tcatggccaa agacctccac ttcgaaggca tgttcaaaaa ggaattacag 950

 acctctattt tttgaagacc gagcagggat tagctgtgtc aggaacttgg 1000

 agttgcactt aaccttgtaa ctttgtttgg agctggcacc tcttgaaata 1050

 aaaaggagga tgcacgagct ggcaggcatg caaaaaaaaa aaaaaaaaaa 1100

 aaaaaaaaa 1109

<210> 3099
<211> 261
<212> PRT
<213> Homo sapien

<400> 3099
 Met Ala Gly Pro Glu Leu Leu Leu Asp Ser Asn Ile Arg Leu Trp
   1               5                  10                  15

 Val Val Leu Pro Ile Val Ile Ile Thr Phe Phe Val Gly Met Ile
                  20                  25                  30

 Arg His Tyr Val Ser Ile Leu Leu Gln Ser Asp Lys Lys Leu Thr
                  35                  40                  45

 Gln Glu Gln Val Ser Asp Ser Gln Val Leu Ile Arg Ser Arg Val
                  50                  55                  60

 Leu Arg Glu Asn Gly Lys Tyr Ile Pro Lys Gln Ser Phe Leu Thr
                  65                  70                  75

 Arg Lys Tyr Tyr Phe Asn Asn Pro Glu Asp Gly Phe Phe Lys Lys
                  80                  85                  90

 Thr Lys Arg Lys Val Val Pro Pro Ser Pro Met Thr Asp Pro Thr
                  95                 100                 105

 Met Leu Thr Asp Met Met Lys Gly Asn Val Thr Asn Val Leu Pro
                 110                 115                 120

 Met Ile Leu Ile Gly Gly Trp Ile Asn Met Thr Phe Ser Gly Phe
                 125                 130                 135

 Val Thr Thr Lys Val Pro Phe Pro Leu Thr Leu Arg Phe Lys Pro
                 140                 145                 150

 Met Leu Gln Gln Gly Ile Glu Leu Leu Thr Leu Asp Ala Ser Trp
                 155                 160                 165

 Val Ser Ser Ala Ser Trp Tyr Phe Leu Asn Val Phe Gly Leu Arg
                 170                 175                 180

 Ser Ile Tyr Ser Leu Ile Leu Gly Gln Asp Asn Ala Ala Asp Gln
                 185                 190                 195

 Ser Arg Met Met Gln Glu Gln Met Thr Gly Ala Ala Met Ala Met
                 200                 205                 210

 Pro Ala Asp Thr Asn Lys Ala Phe Lys Thr Glu Trp Glu Ala Leu
                 215                 220                 225

 Glu Leu Thr Asp His Gln Trp Ala Leu Asp Asp Val Glu Glu Glu
                 230                 235                 240

 Leu Met Ala Lys Asp Leu His Phe Glu Gly Met Phe Lys Lys Glu
                 245                 250                 255

 Leu Gln Thr Ser Ile Phe
                 260

<210> 3100
<211> 3655
<212> DNA
<213> Homo sapien

<400> 3100
 ggcacgaggc gctaggtaga gcgccgggac ctgtgacagg gctggtagca 50

 gcgcacagga aaggcggctt ttagccaggt atttcagtgt ctgtagacaa 100

 gatggaatca tctccattta atagacggca atggacctca ctatcattga 150

 gggtaacagc caaagaactt tctcttgtca acaagaacaa gtcatcggct 200

 attgtggaaa tattctccaa gtaccagaaa gcagctgaag aaacaaacat 250

 ggagaagaag agaagtaaca ccgaaaatct ctcccagcac tttagaaagg 300

 ggaccctgac tgtgttaaag aagaagtggg agaacccagg gctgggagca 350

 gagtctcaca cagactctct acggaacagc agcactgaga ttaggcacag 400

 agcagaccat cctcctgctg aagtgacaag ccacgctgct tctggagcca 450

 aagctgacca agaagaacaa atccacccca gatctagact caggtcacct 500

 cctgaagccc tcgttcaggg tcgatatccc cacatcaagg acggtgagga 550

 tcttaaagac cactcaacag aaagtaaaaa aatggaaaat tgtctaggag 600

 aatccaggca tgaagtagaa aaatcagaaa tcagtgaaaa cacagatgct 650

 tcgggcaaaa tagagaaata taatgttccg ctgaacaggc ttaagatgat 700

 gtttgagaaa ggtgaaccaa ctcaaactaa gattctccgg gcccaaagcc 750

 gaagtgcaag tggaaggaag atctctgaaa acagctattc tctagatgac 800

 ctggaaatag gcccaggtca gttgtcatct tctacatttg actcggagaa 850

 aaatgagagt agacgaaatc tggaacttcc acgcctctca gaaacctcta 900

 taaaggatcg aatggccaag taccaggcag ctgtgtccaa acaaagcagc 950

 tcaaccaact atacaaatga gctgaaagcc agtggtggcg aaatcaaaat 1000

 tcataaaatg gagcaaaagg agaatgtgcc cccaggtcct gaggtctgca 1050

 tcacccatca ggaaggggaa aagatttctg caaatgagaa tagcctggca 1100

 gtccgttcca cccctgccga agatgactcc cgtgactccc aggttaagag 1150

 tgaggttcaa cagcctgtcc atcccaagcc actaagtcca gattccagag 1200

 cctccagtct ttctgaaagt tctcctccca aagcaatgaa gaagtttcag 1250

 gcacctgcaa gagagacctg cgtggaatgt cagaagacag tctatccaat 1300

 ggagcgtctc ttggccaacc agcaggtgtt tcacatcagc tgcttccgtt 1350

 gctcctattg caacaacaaa ctcagtctag gaacatatgc atctttacat 1400

 ggaagaatct attgtaagcc tcacttcaat caactcttta aatctaaggg 1450

 caactatgat gaaggctttg ggcacagacc acacaaggat ctatgggcaa 1500

 gcaaaaatga aaacgaagag attttggaga gaccagccca gcttgcaaat 1550

 gcaagggaga cccctcacag cccaggggta gaagatgccc ctattgctaa 1600

 ggtgggtgtc ctggctgcaa gtatggaagc caaggcctcc tctcagcagg 1650

 agaaggaaga caagccagct gaaaccaaga agctgaggat cgcctggcca 1700

 ccccccactg aacttggaag ttcaggaagt gccttggagg aagggatcaa 1750

 aatgtcaaag cccaaatggc ctcctgaaga cgaaatcagc aagcccgaag 1800

 ttcctgagga tgtcgatcta gatctgaaga agctaagacg atcttcttca 1850

 ctgaaggaaa gaagccgccc attcactgta gcagcttcat ttcaaagcac 1900

 ctctgtcaag agcccaaaaa ctgtgtcccc acctatcagg aaaggctgga 1950

 gcatgtcaga gcagagtgaa gaatctgtgg gtggaagagt tgcagaaagg 2000

 aaacaagtgg aaaatgccaa ggcttctaag aagaatggga atgtgggaaa 2050

 aacaacctgg caaaacaaag aatctaaagg agagacaggg aagagaagta 2100

 aggaaggtca tagtttggag atggagaatg agaatcttgt agaaaatggt 2150

 gcagactccg atgaagatga taacagcttc ctcaaacaac aatctccaca 2200

 agaacccaag tctctgaatt ggtcgagttt tgtagacaac acctttgctg 2250

 aagaattcac tactcagaat cagaaatccc aggatgtgga actctgggag 2300

 ggagaagtgg tcaaagagct ctctgtggaa gaacagataa agagaaatcg 2350

 gtattatgat gaggatgagg atgaagagtg acaaattgca atgatgctgg 2400

 gccttaaatt catgttagtg ttagcgagcc actgcccttt gtcaaaatgt 2450

 gatgcacata agcaggtatc ccagcatgaa atgtaattta cttggaagta 2500

 actttggaaa agaattcctt cttaaaatca aaaacaaaac aaaaaaacac 2550

 aaaaaacaca ttctaaatac tagagataac tttacttaaa ttcttcattt 2600

 tagcagtgat gatatgcata agtgctgtaa ggcttgtaac tggggaaata 2650

 ttccacctga taatagccca gattctactg tattcccaaa aggcaatatt 2700

 aaggtagata gatgattagt agtatattgt tacacactat tttggaatta 2750

 gagaacatac agaaggaatt taggggctta aacattacga ctgaatgcac 2800

 tttagtataa agggcacagt ttgtatattt ttaaatgaat accaatttaa 2850

 ttttttagta tttacctgtt aagagattat ttagtcttta aattttttag 2900

 gttaattttc ttgctgtgat atatatgagg aatttactac tttatgtcct 2950

 gctctctaaa ctacatcctg aactcgacgt cctgaggtat aatacaacag 3000

 agcacttttt gaggcaattg aaaaaccaac ctacactctt cggtgcttag 3050

 agagatctgc tgtctcccaa ataagctttt gtatctgcca gtgaatttac 3100

 tgtactccaa atgattgctt tcttttctgg tgatatctgt gcttctcata 3150

 attactgaaa gctgcaatat tttagtaata ccttcgggat cactgtcccc 3200

 catcttccgt gttagagcaa agtgaagagt ttaaaggagg aagaagaaag 3250

 aactgtctta caccacttga gctcagacct ctaaaccctg tatttccctt 3300

 atgatgtccc ctttttgaga cactaatttt taaatactta ctagctctga 3350

 aatatattga tttttatcac agtattctca gggtgaaatt aaaccaacta 3400

 taggcctttt tcttgggatg attttctagt cttaaggttt ggggacatta 3450

 taaacttgag tacatttgtt gtacacagtt gatattccaa attgtatgga 3500

 tgggagggag aggtgtctta agctgtaggc ttttctttgt actgcattta 3550

 tagagattta gctttaatat tttttagaga tgtaaaacat tctgctttct 3600

 tagtcttacc tagtctgaaa catttttatt caataaagat tttaattaaa 3650

 atttg 3655

<210> 3101
<211> 759
<212> PRT
<213> Homo sapien

<400> 3101
 Met Glu Ser Ser Pro Phe Asn Arg Arg Gln Trp Thr Ser Leu Ser
   1               5                  10                  15

 Leu Arg Val Thr Ala Lys Glu Leu Ser Leu Val Asn Lys Asn Lys
                  20                  25                  30

 Ser Ser Ala Ile Val Glu Ile Phe Ser Lys Tyr Gln Lys Ala Ala
                  35                  40                  45

 Glu Glu Thr Asn Met Glu Lys Lys Arg Ser Asn Thr Glu Asn Leu
                  50                  55                  60

 Ser Gln His Phe Arg Lys Gly Thr Leu Thr Val Leu Lys Lys Lys
                  65                  70                  75

 Trp Glu Asn Pro Gly Leu Gly Ala Glu Ser His Thr Asp Ser Leu
                  80                  85                  90

 Arg Asn Ser Ser Thr Glu Ile Arg His Arg Ala Asp His Pro Pro
                  95                 100                 105

 Ala Glu Val Thr Ser His Ala Ala Ser Gly Ala Lys Ala Asp Gln
                 110                 115                 120

 Glu Glu Gln Ile His Pro Arg Ser Arg Leu Arg Ser Pro Pro Glu
                 125                 130                 135

 Ala Leu Val Gln Gly Arg Tyr Pro His Ile Lys Asp Gly Glu Asp
                 140                 145                 150

 Leu Lys Asp His Ser Thr Glu Ser Lys Lys Met Glu Asn Cys Leu
                 155                 160                 165

 Gly Glu Ser Arg His Glu Val Glu Lys Ser Glu Ile Ser Glu Asn
                 170                 175                 180

 Thr Asp Ala Ser Gly Lys Ile Glu Lys Tyr Asn Val Pro Leu Asn
                 185                 190                 195

 Arg Leu Lys Met Met Phe Glu Lys Gly Glu Pro Thr Gln Thr Lys
                 200                 205                 210

 Ile Leu Arg Ala Gln Ser Arg Ser Ala Ser Gly Arg Lys Ile Ser
                 215                 220                 225

 Glu Asn Ser Tyr Ser Leu Asp Asp Leu Glu Ile Gly Pro Gly Gln
                 230                 235                 240

 Leu Ser Ser Ser Thr Phe Asp Ser Glu Lys Asn Glu Ser Arg Arg
                 245                 250                 255

 Asn Leu Glu Leu Pro Arg Leu Ser Glu Thr Ser Ile Lys Asp Arg
                 260                 265                 270

 Met Ala Lys Tyr Gln Ala Ala Val Ser Lys Gln Ser Ser Ser Thr
                 275                 280                 285

 Asn Tyr Thr Asn Glu Leu Lys Ala Ser Gly Gly Glu Ile Lys Ile
                 290                 295                 300

 His Lys Met Glu Gln Lys Glu Asn Val Pro Pro Gly Pro Glu Val
                 305                 310                 315

 Cys Ile Thr His Gln Glu Gly Glu Lys Ile Ser Ala Asn Glu Asn
                 320                 325                 330

 Ser Leu Ala Val Arg Ser Thr Pro Ala Glu Asp Asp Ser Arg Asp
                 335                 340                 345

 Ser Gln Val Lys Ser Glu Val Gln Gln Pro Val His Pro Lys Pro
                 350                 355                 360

 Leu Ser Pro Asp Ser Arg Ala Ser Ser Leu Ser Glu Ser Ser Pro
                 365                 370                 375

 Pro Lys Ala Met Lys Lys Phe Gln Ala Pro Ala Arg Glu Thr Cys
                 380                 385                 390

 Val Glu Cys Gln Lys Thr Val Tyr Pro Met Glu Arg Leu Leu Ala
                 395                 400                 405

 Asn Gln Gln Val Phe His Ile Ser Cys Phe Arg Cys Ser Tyr Cys
                 410                 415                 420

 Asn Asn Lys Leu Ser Leu Gly Thr Tyr Ala Ser Leu His Gly Arg
                 425                 430                 435

 Ile Tyr Cys Lys Pro His Phe Asn Gln Leu Phe Lys Ser Lys Gly
                 440                 445                 450

 Asn Tyr Asp Glu Gly Phe Gly His Arg Pro His Lys Asp Leu Trp
                 455                 460                 465

 Ala Ser Lys Asn Glu Asn Glu Glu Ile Leu Glu Arg Pro Ala Gln
                 470                 475                 480

 Leu Ala Asn Ala Arg Glu Thr Pro His Ser Pro Gly Val Glu Asp
                 485                 490                 495

 Ala Pro Ile Ala Lys Val Gly Val Leu Ala Ala Ser Met Glu Ala
                 500                 505                 510

 Lys Ala Ser Ser Gln Gln Glu Lys Glu Asp Lys Pro Ala Glu Thr
                 515                 520                 525

 Lys Lys Leu Arg Ile Ala Trp Pro Pro Pro Thr Glu Leu Gly Ser
                 530                 535                 540

 Ser Gly Ser Ala Leu Glu Glu Gly Ile Lys Met Ser Lys Pro Lys
                 545                 550                 555

 Trp Pro Pro Glu Asp Glu Ile Ser Lys Pro Glu Val Pro Glu Asp
                 560                 565                 570

 Val Asp Leu Asp Leu Lys Lys Leu Arg Arg Ser Ser Ser Leu Lys
                 575                 580                 585

 Glu Arg Ser Arg Pro Phe Thr Val Ala Ala Ser Phe Gln Ser Thr
                 590                 595                 600

 Ser Val Lys Ser Pro Lys Thr Val Ser Pro Pro Ile Arg Lys Gly
                 605                 610                 615

 Trp Ser Met Ser Glu Gln Ser Glu Glu Ser Val Gly Gly Arg Val
                 620                 625                 630

 Ala Glu Arg Lys Gln Val Glu Asn Ala Lys Ala Ser Lys Lys Asn
                 635                 640                 645

 Gly Asn Val Gly Lys Thr Thr Trp Gln Asn Lys Glu Ser Lys Gly
                 650                 655                 660

 Glu Thr Gly Lys Arg Ser Lys Glu Gly His Ser Leu Glu Met Glu
                 665                 670                 675

 Asn Glu Asn Leu Val Glu Asn Gly Ala Asp Ser Asp Glu Asp Asp
                 680                 685                 690

 Asn Ser Phe Leu Lys Gln Gln Ser Pro Gln Glu Pro Lys Ser Leu
                 695                 700                 705

 Asn Trp Ser Ser Phe Val Asp Asn Thr Phe Ala Glu Glu Phe Thr
                 710                 715                 720

 Thr Gln Asn Gln Lys Ser Gln Asp Val Glu Leu Trp Glu Gly Glu
                 725                 730                 735

 Val Val Lys Glu Leu Ser Val Glu Glu Gln Ile Lys Arg Asn Arg
                 740                 745                 750

 Tyr Tyr Asp Glu Asp Glu Asp Glu Glu
                 755

<210> 3102
<211> 1721
<212> DNA
<213> Homo sapien

<400> 3102
 agacgggctg caagagggag ccggcccgac gcggaccgct tccctgcagt 50

 gccccgagtc ccgggcccgc gccgccgccg cccggctccg ctcgcggccc 100

 ctctgtctgc aggcgtgccc cggcggcggc ggagagccgt cctcggccga 150

 ggaggctggg aaacgcgagc gcaggcggca gagaggcctc aacgccgtcc 200

 ctttcgccac cgccttttcc ttgcctcgcg ccgctgtgca tttctctcct 250

 tttcctttgt ttttttggcc cctcgcgggt gtgggcattg ttggttagca 300

 aaagtgcagc ctcaagatgg ctgatggcaa cgaggatctg cgggctgacg 350

 acttgcctgg gccagccttc gagagctatg agtccatgga gcttgcctgc 400

 cccgctgagc gcagcggcca cgtagccgtc agcgacgggc gccacatgtt 450

 cgtctggggc ggctacaaga gtaatcaagt cagaggatta tatgactttt 500

 atctgcctag agaagaacta tggatctaca acatggagac tggaagatgg 550

 aaaaaaatca acactgaagg tgatgttcct ccttctatgt caggaagctg 600

 tgctgtgtgt gtagacaggg tgctgtactt gtttggagga caccattcaa 650

 gaggcaatac caataagttc tacatgctgg attcaaggtc tacagacaga 700

 gtgttacagt gggaaagaat tgattgccaa ggaattcctc catcatcaaa 750

 ggacaaactt ggtgtctggg tatataaaaa caagttaata ttttttggag 800

 ggtatggata tttgcctgaa gataaagtat tgggaacttt tgaattcgat 850

 gaaacatctt tttggaattc aagtcatcca agaggatgga atgatcatgt 900

 acatatttta gatactgaaa catttacctg gagccagcct ataactactg 950

 gtaaagcacc ttcacctcgt gctgcccatg cctgtgcaac tgtcggaaat 1000

 agaggcttcg tgtttggagg caggtatcga gatgctagaa tgaatgatct 1050

 tcactatctt aatctggata catgggagtg gaatgaatta attccacaag 1100

 gcatatgccc agttggtcga tcttggcact cactaacacc agtttcttca 1150

 gatcatcttt ttctctttgg aggatttacc actgataaac agccactaag 1200

 tgatgcctgg acttactgca tcagtaaaaa tgaatggata caatttaatc 1250

 atccatatac cgaaaaacca aggttatggc acacagcttg tgccagcgat 1300

 gaaggagaag taattgtttt tggtggatgt gccaacaact tgcttgtcca 1350

 tcacagagct gcacacagta atgaaatact aatattttca gttcaaccaa 1400

 aatctcttgt acggctaagc ttagaagcag tcatttgctt taaagaaatg 1450

 ttagccaact catggaactg ccttccaaaa cacttacttc acagtgttaa 1500

 tcagaggttt ggtagtaaca acacttctgg atcttaaggc ttcataaata 1550

 atgcctatga tcaccttgca tggacagcaa tcctgtaaac atcacagagt 1600

 ggcatcattt gtataattat atgcattgtt gtagtttgca cctgttggtt 1650

 ttaatgtgca tgtgaatggc ctagagaacc tatttttgtg tctaaagttt 1700

 acaataaatg tatttaacac c 1721

<210> 3103
<211> 406
<212> PRT
<213> Homo sapien

<400> 3103
 Met Ala Asp Gly Asn Glu Asp Leu Arg Ala Asp Asp Leu Pro Gly
   1               5                  10                  15

 Pro Ala Phe Glu Ser Tyr Glu Ser Met Glu Leu Ala Cys Pro Ala
                  20                  25                  30

 Glu Arg Ser Gly His Val Ala Val Ser Asp Gly Arg His Met Phe
                  35                  40                  45

 Val Trp Gly Gly Tyr Lys Ser Asn Gln Val Arg Gly Leu Tyr Asp
                  50                  55                  60

 Phe Tyr Leu Pro Arg Glu Glu Leu Trp Ile Tyr Asn Met Glu Thr
                  65                  70                  75

 Gly Arg Trp Lys Lys Ile Asn Thr Glu Gly Asp Val Pro Pro Ser
                  80                  85                  90

 Met Ser Gly Ser Cys Ala Val Cys Val Asp Arg Val Leu Tyr Leu
                  95                 100                 105

 Phe Gly Gly His His Ser Arg Gly Asn Thr Asn Lys Phe Tyr Met
                 110                 115                 120

 Leu Asp Ser Arg Ser Thr Asp Arg Val Leu Gln Trp Glu Arg Ile
                 125                 130                 135

 Asp Cys Gln Gly Ile Pro Pro Ser Ser Lys Asp Lys Leu Gly Val
                 140                 145                 150

 Trp Val Tyr Lys Asn Lys Leu Ile Phe Phe Gly Gly Tyr Gly Tyr
                 155                 160                 165

 Leu Pro Glu Asp Lys Val Leu Gly Thr Phe Glu Phe Asp Glu Thr
                 170                 175                 180

 Ser Phe Trp Asn Ser Ser His Pro Arg Gly Trp Asn Asp His Val
                 185                 190                 195

 His Ile Leu Asp Thr Glu Thr Phe Thr Trp Ser Gln Pro Ile Thr
                 200                 205                 210

 Thr Gly Lys Ala Pro Ser Pro Arg Ala Ala His Ala Cys Ala Thr
                 215                 220                 225

 Val Gly Asn Arg Gly Phe Val Phe Gly Gly Arg Tyr Arg Asp Ala
                 230                 235                 240

 Arg Met Asn Asp Leu His Tyr Leu Asn Leu Asp Thr Trp Glu Trp
                 245                 250                 255

 Asn Glu Leu Ile Pro Gln Gly Ile Cys Pro Val Gly Arg Ser Trp
                 260                 265                 270

 His Ser Leu Thr Pro Val Ser Ser Asp His Leu Phe Leu Phe Gly
                 275                 280                 285

 Gly Phe Thr Thr Asp Lys Gln Pro Leu Ser Asp Ala Trp Thr Tyr
                 290                 295                 300

 Cys Ile Ser Lys Asn Glu Trp Ile Gln Phe Asn His Pro Tyr Thr
                 305                 310                 315

 Glu Lys Pro Arg Leu Trp His Thr Ala Cys Ala Ser Asp Glu Gly
                 320                 325                 330

 Glu Val Ile Val Phe Gly Gly Cys Ala Asn Asn Leu Leu Val His
                 335                 340                 345

 His Arg Ala Ala His Ser Asn Glu Ile Leu Ile Phe Ser Val Gln
                 350                 355                 360

 Pro Lys Ser Leu Val Arg Leu Ser Leu Glu Ala Val Ile Cys Phe
                 365                 370                 375

 Lys Glu Met Leu Ala Asn Ser Trp Asn Cys Leu Pro Lys His Leu
                 380                 385                 390

 Leu His Ser Val Asn Gln Arg Phe Gly Ser Asn Asn Thr Ser Gly
                 395                 400                 405

 Ser


<210> 3104
<211> 2605
<212> DNA
<213> Homo sapien

<400> 3104
 gcggagctcc gcatccaacc ccgggccgcg gccaacttct ctggactgga 50

 ccagaagttt ctagccggcc agttgctacc tccctttatc tcctccttcc 100

 cctctggcag cgaggaggct atttccagac acttccaccc ctctctggcc 150

 acgtcacccc cgcctttaat tcataaaggt gcccggcgcc ggcttcccgg 200

 acacgtcggc ggcggagagg ggcccacggc ggcggcccgg ccagagactc 250

 ggcgcccgga gccagcgccc cgcacccgcg ccccagcggg cagaccccaa 300

 cccagcatga gcgccgccac ccactcgccc atgatgcagg tggcgtccgg 350

 caacggtgac cgcgaccctt tgccccccgg atgggagatc aagatcgacc 400

 cgcagaccgg ctggcccttc ttcgtggacc acaacagccg caccactacg 450

 tggaacgacc cgcgcgtgcc ctctgagggc cccaaggaga ctccatcctc 500

 tgccaatggc ccttcccggg agggctctag gctgccgcct gctagggaag 550

 gccaccctgt gtacccccag ctccgaccag gctacattcc cattcctgtg 600

 ctccatgaag gcgctgagaa ccggcaggtg caccctttcc atgtctatcc 650

 ccagcctggg atgcagcgat tccgaactga ggcggcagca gcggctcctc 700

 agaggtccca gtcacctctg cggggcatgc cagaaaccac tcagccagat 750

 aaacagtgtg gacaggtggc agcggcggcg gcagcccagc ccccagcctc 800

 ccacggacct gagcggtccc agtctccagc tgcctctgac tgctcatcct 850

 catcctcctc ggccagcctg ccttcctccg gcaggagcag cctgggcagt 900

 caccagctcc cgcgggggta catctccatt ccggtgatac acgagcagaa 950

 cgttacccgg ccagcagccc agccctcctt ccaccaagcc cagaagacgc 1000

 actacccagc gcagcagggg gagtaccaga cccaccagcc tgtgtaccac 1050

 aagatccagg gggatgactg ggagccccgg cccctgcggg cggcatcccc 1100

 gttcaggtca tctgtccagg gtgcatcgag ccgggagggc tcaccagcca 1150

 ggagcagcac gccactccac tccccctcgc ccatccgtgt gcacaccgtg 1200

 gtcgacaggc ctcagcagcc catgacccat cgagaaactg cacctgtttc 1250

 ccagcctgaa aacaaaccag aaagtaagcc aggcccagtt ggaccagaac 1300

 tccctcctgg acacatccca attcaagtga tccgcaaaga ggtggattct 1350

 aaacctgttt cccagaagcc cccacctccc tctgagaagg tagaggtgaa 1400

 agttccccct gctccagttc cttgtcctcc tcccagccct ggcccttctg 1450

 ctgtcccctc ttcccccaag agtgtggcta cagaagagag ggcagccccc 1500

 agcactgccc ctgcagaagc tacacctcca aaaccaggag aagccgaggc 1550

 tcccccaaaa catccaggag tgctgaaagt ggaagccatc ctggagaagg 1600

 tgcaggggct ggagcaggct gtagacaact ttgaaggcaa gaagactgac 1650

 aaaaagtacc tgatgatcga agagtatttg accaaagagc tgctggccct 1700

 ggattcagtg gaccccgagg gacgagccga tgtgcgtcag gccaggagag 1750

 acggtgtcag gaaggttcag accatcttgg aaaaacttga acagaaagcc 1800

 attgatgtcc caggtcaagt ccaggtctat gaactccagc ccagcaacct 1850

 tgaagcagat cagccactgc aggcaatcat ggagatgggt gccgtggcag 1900

 cagacaaggg caagaaaaat gctggaaatg cagaagatcc ccacacagaa 1950

 acccagcagc cagaagccac agcagcagcg acttcaaacc ccagcagcat 2000

 gacagacacc cctggtaacc cagcagcacc gtagcctctg ccctgtaaaa 2050

 atcagactcg gaaccgatgt gtgctttagg gaattttaag ttgcatgcat 2100

 ttcagagact ttaagtcagt tggtttttat tagctgcttg gtatgcagta 2150

 acttgggtgg aggcaaaaca ctaataaaag ggctaaaaag gaaaatgatg 2200

 cttttcttct atattcttac tctgtacaaa taaagaagtt gcttgttgtt 2250

 tgagaagttt aaccccgttg cttgttctgc agccctgtct acttgggcac 2300

 ccccaccacc tgttagctgt ggttgtgcac tgtcttttgt agctctggac 2350

 tggaggggta gatggggagt caattaccca tcacataaat atgaaacatt 2400

 tatcagaaat gttgccattt taatgagatg attttcttca tctcataatt 2450

 aaaatacctg actttagaga gagtaaaatg tgccaggagc cataggaata 2500

 tctgtatgtt ggatgacttt aatgctacat tttaaaaaaa gaaaataaag 2550

 taataatata actcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2600

 aaaaa 2605

<210> 3105
<211> 575
<212> PRT
<213> Homo sapien

<400> 3105
 Met Ser Ala Ala Thr His Ser Pro Met Met Gln Val Ala Ser Gly
   1               5                  10                  15

 Asn Gly Asp Arg Asp Pro Leu Pro Pro Gly Trp Glu Ile Lys Ile
                  20                  25                  30

 Asp Pro Gln Thr Gly Trp Pro Phe Phe Val Asp His Asn Ser Arg
                  35                  40                  45

 Thr Thr Thr Trp Asn Asp Pro Arg Val Pro Ser Glu Gly Pro Lys
                  50                  55                  60

 Glu Thr Pro Ser Ser Ala Asn Gly Pro Ser Arg Glu Gly Ser Arg
                  65                  70                  75

 Leu Pro Pro Ala Arg Glu Gly His Pro Val Tyr Pro Gln Leu Arg
                  80                  85                  90

 Pro Gly Tyr Ile Pro Ile Pro Val Leu His Glu Gly Ala Glu Asn
                  95                 100                 105

 Arg Gln Val His Pro Phe His Val Tyr Pro Gln Pro Gly Met Gln
                 110                 115                 120

 Arg Phe Arg Thr Glu Ala Ala Ala Ala Ala Pro Gln Arg Ser Gln
                 125                 130                 135

 Ser Pro Leu Arg Gly Met Pro Glu Thr Thr Gln Pro Asp Lys Gln
                 140                 145                 150

 Cys Gly Gln Val Ala Ala Ala Ala Ala Ala Gln Pro Pro Ala Ser
                 155                 160                 165

 His Gly Pro Glu Arg Ser Gln Ser Pro Ala Ala Ser Asp Cys Ser
                 170                 175                 180

 Ser Ser Ser Ser Ser Ala Ser Leu Pro Ser Ser Gly Arg Ser Ser
                 185                 190                 195

 Leu Gly Ser His Gln Leu Pro Arg Gly Tyr Ile Ser Ile Pro Val
                 200                 205                 210

 Ile His Glu Gln Asn Val Thr Arg Pro Ala Ala Gln Pro Ser Phe
                 215                 220                 225

 His Gln Ala Gln Lys Thr His Tyr Pro Ala Gln Gln Gly Glu Tyr
                 230                 235                 240

 Gln Thr His Gln Pro Val Tyr His Lys Ile Gln Gly Asp Asp Trp
                 245                 250                 255

 Glu Pro Arg Pro Leu Arg Ala Ala Ser Pro Phe Arg Ser Ser Val
                 260                 265                 270

 Gln Gly Ala Ser Ser Arg Glu Gly Ser Pro Ala Arg Ser Ser Thr
                 275                 280                 285

 Pro Leu His Ser Pro Ser Pro Ile Arg Val His Thr Val Val Asp
                 290                 295                 300

 Arg Pro Gln Gln Pro Met Thr His Arg Glu Thr Ala Pro Val Ser
                 305                 310                 315

 Gln Pro Glu Asn Lys Pro Glu Ser Lys Pro Gly Pro Val Gly Pro
                 320                 325                 330

 Glu Leu Pro Pro Gly His Ile Pro Ile Gln Val Ile Arg Lys Glu
                 335                 340                 345

 Val Asp Ser Lys Pro Val Ser Gln Lys Pro Pro Pro Pro Ser Glu
                 350                 355                 360

 Lys Val Glu Val Lys Val Pro Pro Ala Pro Val Pro Cys Pro Pro
                 365                 370                 375

 Pro Ser Pro Gly Pro Ser Ala Val Pro Ser Ser Pro Lys Ser Val
                 380                 385                 390

 Ala Thr Glu Glu Arg Ala Ala Pro Ser Thr Ala Pro Ala Glu Ala
                 395                 400                 405

 Thr Pro Pro Lys Pro Gly Glu Ala Glu Ala Pro Pro Lys His Pro
                 410                 415                 420

 Gly Val Leu Lys Val Glu Ala Ile Leu Glu Lys Val Gln Gly Leu
                 425                 430                 435

 Glu Gln Ala Val Asp Asn Phe Glu Gly Lys Lys Thr Asp Lys Lys
                 440                 445                 450

 Tyr Leu Met Ile Glu Glu Tyr Leu Thr Lys Glu Leu Leu Ala Leu
                 455                 460                 465

 Asp Ser Val Asp Pro Glu Gly Arg Ala Asp Val Arg Gln Ala Arg
                 470                 475                 480

 Arg Asp Gly Val Arg Lys Val Gln Thr Ile Leu Glu Lys Leu Glu
                 485                 490                 495

 Gln Lys Ala Ile Asp Val Pro Gly Gln Val Gln Val Tyr Glu Leu
                 500                 505                 510

 Gln Pro Ser Asn Leu Glu Ala Asp Gln Pro Leu Gln Ala Ile Met
                 515                 520                 525

 Glu Met Gly Ala Val Ala Ala Asp Lys Gly Lys Lys Asn Ala Gly
                 530                 535                 540

 Asn Ala Glu Asp Pro His Thr Glu Thr Gln Gln Pro Glu Ala Thr
                 545                 550                 555

 Ala Ala Ala Thr Ser Asn Pro Ser Ser Met Thr Asp Thr Pro Gly
                 560                 565                 570

 Asn Pro Ala Ala Pro
                 575

<210> 3106
<211> 2093
<212> DNA
<213> Homo sapien

<400> 3106
 cgctgtttcg tgggaccagg attgaaacaa gatggcgggt tcgtggtgag 50

 aagccgtcaa gcaggagtag aaattggtat gcttagaagc agattctaaa 100

 agcagtttct cttcagaaca tcttttttca taccacttga taagcatctt 150

 gaaacaccat ggctgtagct gcagtaaaat gggtgatgtc aaagagaact 200

 atcttgaaac atttatttcc agtccaaaat tcgggcgtac atgtgcagat 250

 ggagctttat attgtgtttg tcataaatct acgtattctc ctctaccaga 300

 tgactataat tgcaacgtag agcttgctct gacttctgat ggcaggacaa 350

 tagtatgcta ccacccttct gtggacattc catatgaaca cacaaaacct 400

 atccctcggc cagatcctgt gcataataat gaagaaacac atgatcaagt 450

 gctgaaaacc agattggaag aaaaagttga acaccttgag gaaggaccta 500

 tgatagaaca acttagcaaa atgttcttta ctactaagca ccgttggtat 550

 cctcatggac ggtatcacag atgtcgtaag aatctgaatc ctccaaaaga 600

 cagatgatgc ggaggttcct gggggaatca aagagaaatg tgcctcattt 650

 gccatttgag aaaatgcagt ctggtgtatt cagtaatata tagtaaagta 700

 ataatgataa aatatctttt catatattag aatgtgtact tttatataaa 750

 gtaattctgg atttgacatt ctcatttaga gaaacctatt ttcttttttc 800

 tttttctatt ttagtgtttc atttatgtgc ggtctccaat ttaggacttt 850

 tccatagtgc caaagccata catattcagt agaacatcaa taaattacat 900

 cagaaattca acactttatt ataaaacggg cttcgtgtta gataattttg 950

 ctaaacagta ggctactgta agtgttctga gcatatttaa gacaggctag 1000

 cattttcaat ttacaatatt ttcaactgat agtaggttta ttgggatgta 1050

 accctatgat aagttgagaa acatctcttt ttgtgtgtct actgtgattt 1100

 aagtattttt aatcatcagc caagcattgt tagtagtata aatatgatta 1150

 ataaaaatgt gcatggcttt cctgaaggag attttttaat tgcctttgag 1200

 aataaactca taaggtctac caagaaaata aatgttatga tgtttcagtt 1250

 ggcttctagg aaataattaa attagtgata ttttaatcag gttttactat 1300

 ctgctaggcc ccttccatca attcttatta aattctcaaa ataatccttt 1350

 gaaaagggag tataattaca ttttacagtg actcgaacct tacccaaaca 1400

 agtgggagag ccaggagcca aactatcagg ctccaaagct tttttttagt 1450

 gcatcacaat gacaaagggg tggttttctt tcacccaaga atgtgctttc 1500

 ctggaaattt ttctagatag aatattatgt aatttgtttt gaaggttttt 1550

 tttcctgact gtcttaaaga ttatgctagc tttagaacac atgcaaacag 1600

 ctgcagctct gtgattaaaa tgttaaggtc actagaatag tgttaggaaa 1650

 atgttaatag ataattctgc tgcctctatt agcttatgta tgatccttaa 1700

 tagcattgct tccccttcag tttctattta ggaggtgaag aatcttttaa 1750

 taaggtagaa agttgcttta tttaaatttg tactgtagaa tgtttgtgat 1800

 acagtatttg taaaattgat atgaaaaata atttctcaaa gtctattgtt 1850

 tgatctagtt attttaataa aggaactcta gaagtttcaa gtggccagtg 1900

 aagtgtgagg aatagagagt aaaggaaata attaataatg gtgaccctct 1950

 gttaagtggt ttactttttc cattaatata aatttcattt ggaaagatta 2000

 aaaaaacaag tttgattgaa cttgataaat cagaaatatt taaaaaaaaa 2050

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2093

<210> 3107
<211> 142
<212> PRT
<213> Homo sapien

<400> 3107
 Met Gly Asp Val Lys Glu Asn Tyr Leu Glu Thr Phe Ile Ser Ser
   1               5                  10                  15

 Pro Lys Phe Gly Arg Thr Cys Ala Asp Gly Ala Leu Tyr Cys Val
                  20                  25                  30

 Cys His Lys Ser Thr Tyr Ser Pro Leu Pro Asp Asp Tyr Asn Cys
                  35                  40                  45

 Asn Val Glu Leu Ala Leu Thr Ser Asp Gly Arg Thr Ile Val Cys
                  50                  55                  60

 Tyr His Pro Ser Val Asp Ile Pro Tyr Glu His Thr Lys Pro Ile
                  65                  70                  75

 Pro Arg Pro Asp Pro Val His Asn Asn Glu Glu Thr His Asp Gln
                  80                  85                  90

 Val Leu Lys Thr Arg Leu Glu Glu Lys Val Glu His Leu Glu Glu
                  95                 100                 105

 Gly Pro Met Ile Glu Gln Leu Ser Lys Met Phe Phe Thr Thr Lys
                 110                 115                 120

 His Arg Trp Tyr Pro His Gly Arg Tyr His Arg Cys Arg Lys Asn
                 125                 130                 135

 Leu Asn Pro Pro Lys Asp Arg
                 140

<210> 3108
<211> 2147
<212> DNA
<213> Homo sapien

<400> 3108
 ggctctttta aatgacccca ggcgtcgtgt attgaatcct agactcacgt 50

 ccgtctcgcc ggcgcccgag ccagtccgcg cgcaccgcgt ctgcgtcccc 100

 gaaagccccg cccgcaaggg ctgccctgcc tacctggtct ccgacgtgct 150

 cgtctggagg gcggtgcgag gggccgagcc gacgagatgt tcttgctgcc 200

 tcttccggct gcggggcgag tagtcgtccg acgtctggcc gtagtacgtt 250

 ctgggagccg gagtctctcc accgcagaca tgacgaaggg ccttgtttta 300

 ggaatctatt ccaaagaaaa agaagatgat gtgccacagt tcacaagtgc 350

 aggagagaat tttgataaat tgttagctgg aaagctgaga gagactttga 400

 acatatctgg accacctctg aaggcaggga agactcgaac cttttatggt 450

 ctgcatcagg acttccccag cgtggtgcta gttggcctcg gcaaaaaggc 500

 agctggaatc gacgaacagg aaaactggca tgaaggcaaa gaaaacatca 550

 gagctgctgt tgcagcgggg tgcaggcaga ttcaagacct ggagctctcg 600

 tctgtggagg tggatccctg tggagacgct caggctgctg cggagggagc 650

 ggtgcttggt ctctatgaat acgatgacct aaagcaaaaa aagaagatgg 700

 ctgtgtcggc aaagctctat ggaagtgggg atcaggaggc ctggcagaaa 750

 ggagtcctgt ttgcttctgg gcagaacttg gcacgccaat tgatggagac 800

 gccagccaat gagatgacgc caaccagatt tgccgaaatt attgagaaga 850

 atctcaaaag tgctagtagt aaaaccgagg tccatatcag acccaagtct 900

 tggattgagg aacaggcaat gggatcattc ctcagtgtgg ccaaaggatc 950

 tgacgagccc ccagtcttct tggaaattca ctacaaaggc agccccaatg 1000

 caaacgaacc acccctggtg tttgttggga aaggaattac ctttgacagt 1050

 ggtggtatct ccatcaaggc ttctgcaaat atggacctca tgagggctga 1100

 catgggagga gctgcaacta tatgctcagc catcgtgtct gctgcaaagt 1150

 taaatttgcc cattaatatt ataggtctgg cccctctttg tgaaaatatg 1200

 cccagcggca aggccaacaa gccgggggat gttgttagag ccaaaaacgg 1250

 gaagaccatc caggttgata acactgatgc tgaggggagg ctcatactgg 1300

 ctgatgcgct ctgttacgca cacacgttta acccgaaggt catcctcaat 1350

 gccgccacct taacaggtgc catggatgta gctttgggat caggtgccac 1400

 tggggtcttt accaattcat cctggctctg gaacaaactc ttcgaggcca 1450

 gcattgaaac aggggaccgt gtctggagga tgcctctctt cgaacattat 1500

 acaagacagg ttgtagattg ccagcttgct gatgttaaca acattggaaa 1550

 atacagatct gcaggagcat gtacagctgc agcattcctg aaagaattcg 1600

 taactcatcc taagtgggca catttagaca tagcaggcgt gatgaccaac 1650

 aaagatgaag ttccctatct acggaaaggc atgactggga ggcccacaag 1700

 gactctcatt gagttcttac ttcgtttcag tcaagacaat gcttagttca 1750

 gatactcaaa aatgtcttca ctctgtctta aattggacag ttgaacttaa 1800

 aaggtttttg aataaatgga tgaaaatctt ttaacggaga caaaggatgg 1850

 tatttaaaaa tgtagaacac aatgaaattt gtatgccttg attttttttt 1900

 catttcacac aaagatttat aaaggtaaag ttaatatctt acttgataag 1950

 gatttttaag atactctata aatgattaaa atttttagaa cttcctaatc 2000

 acttttcaga gtatatgttt ttcattgaga agcaaaattg taactcagat 2050

 ttgtgatgct aggaacatga gcaaactgaa aattactatg cacttgtcag 2100

 aaacaataaa tgcaacttgt tgtgaaaaaa aaaaaaaaaa aaaaaaa 2147

<210> 3109
<211> 519
<212> PRT
<213> Homo sapien

<400> 3109
 Met Phe Leu Leu Pro Leu Pro Ala Ala Gly Arg Val Val Val Arg
   1               5                  10                  15

 Arg Leu Ala Val Val Arg Ser Gly Ser Arg Ser Leu Ser Thr Ala
                  20                  25                  30

 Asp Met Thr Lys Gly Leu Val Leu Gly Ile Tyr Ser Lys Glu Lys
                  35                  40                  45

 Glu Asp Asp Val Pro Gln Phe Thr Ser Ala Gly Glu Asn Phe Asp
                  50                  55                  60

 Lys Leu Leu Ala Gly Lys Leu Arg Glu Thr Leu Asn Ile Ser Gly
                  65                  70                  75

 Pro Pro Leu Lys Ala Gly Lys Thr Arg Thr Phe Tyr Gly Leu His
                  80                  85                  90

 Gln Asp Phe Pro Ser Val Val Leu Val Gly Leu Gly Lys Lys Ala
                  95                 100                 105

 Ala Gly Ile Asp Glu Gln Glu Asn Trp His Glu Gly Lys Glu Asn
                 110                 115                 120

 Ile Arg Ala Ala Val Ala Ala Gly Cys Arg Gln Ile Gln Asp Leu
                 125                 130                 135

 Glu Leu Ser Ser Val Glu Val Asp Pro Cys Gly Asp Ala Gln Ala
                 140                 145                 150

 Ala Ala Glu Gly Ala Val Leu Gly Leu Tyr Glu Tyr Asp Asp Leu
                 155                 160                 165

 Lys Gln Lys Lys Lys Met Ala Val Ser Ala Lys Leu Tyr Gly Ser
                 170                 175                 180

 Gly Asp Gln Glu Ala Trp Gln Lys Gly Val Leu Phe Ala Ser Gly
                 185                 190                 195

 Gln Asn Leu Ala Arg Gln Leu Met Glu Thr Pro Ala Asn Glu Met
                 200                 205                 210

 Thr Pro Thr Arg Phe Ala Glu Ile Ile Glu Lys Asn Leu Lys Ser
                 215                 220                 225

 Ala Ser Ser Lys Thr Glu Val His Ile Arg Pro Lys Ser Trp Ile
                 230                 235                 240

 Glu Glu Gln Ala Met Gly Ser Phe Leu Ser Val Ala Lys Gly Ser
                 245                 250                 255

 Asp Glu Pro Pro Val Phe Leu Glu Ile His Tyr Lys Gly Ser Pro
                 260                 265                 270

 Asn Ala Asn Glu Pro Pro Leu Val Phe Val Gly Lys Gly Ile Thr
                 275                 280                 285

 Phe Asp Ser Gly Gly Ile Ser Ile Lys Ala Ser Ala Asn Met Asp
                 290                 295                 300

 Leu Met Arg Ala Asp Met Gly Gly Ala Ala Thr Ile Cys Ser Ala
                 305                 310                 315

 Ile Val Ser Ala Ala Lys Leu Asn Leu Pro Ile Asn Ile Ile Gly
                 320                 325                 330

 Leu Ala Pro Leu Cys Glu Asn Met Pro Ser Gly Lys Ala Asn Lys
                 335                 340                 345

 Pro Gly Asp Val Val Arg Ala Lys Asn Gly Lys Thr Ile Gln Val
                 350                 355                 360

 Asp Asn Thr Asp Ala Glu Gly Arg Leu Ile Leu Ala Asp Ala Leu
                 365                 370                 375

 Cys Tyr Ala His Thr Phe Asn Pro Lys Val Ile Leu Asn Ala Ala
                 380                 385                 390

 Thr Leu Thr Gly Ala Met Asp Val Ala Leu Gly Ser Gly Ala Thr
                 395                 400                 405

 Gly Val Phe Thr Asn Ser Ser Trp Leu Trp Asn Lys Leu Phe Glu
                 410                 415                 420

 Ala Ser Ile Glu Thr Gly Asp Arg Val Trp Arg Met Pro Leu Phe
                 425                 430                 435

 Glu His Tyr Thr Arg Gln Val Val Asp Cys Gln Leu Ala Asp Val
                 440                 445                 450

 Asn Asn Ile Gly Lys Tyr Arg Ser Ala Gly Ala Cys Thr Ala Ala
                 455                 460                 465

 Ala Phe Leu Lys Glu Phe Val Thr His Pro Lys Trp Ala His Leu
                 470                 475                 480

 Asp Ile Ala Gly Val Met Thr Asn Lys Asp Glu Val Pro Tyr Leu
                 485                 490                 495

 Arg Lys Gly Met Thr Gly Arg Pro Thr Arg Thr Leu Ile Glu Phe
                 500                 505                 510

 Leu Leu Arg Phe Ser Gln Asp Asn Ala
                 515

<210> 3110
<211> 6409
<212> DNA
<213> Homo sapien

<400> 3110
 aaagatcttt tttttttttt tttctttttt tttcggcgga gatcctcgtt 50

 ggggctggga aactcctgca aaactcgaga ccaggaagcc agcccgcacc 100

 ccaaccccca ccaaagccac ctactcttct tctgtgggag gccagtccac 150

 atccgctctc acccgagaga gatattcagc tggatccaaa gtgactgatg 200

 aagggaagga aatcatgtca agcgaagcct tgaaaaagct gccctgagac 250

 ggtgtcccgc cgaaagaatg ttggctcaat taagaaacat cagggagata 300

 aattcaaccc agtgtgtcta aaaatgacta caaaacgaag tttgtttgtg 350

 cggttggtac catgtcgctg tctacgaggg gaagaggaga ctgtcactac 400

 tcttgattat tctcattgca gcttagaaca agttccgaaa gagattttta 450

 cttttgaaaa aaccttggag gaactctatt tagatgctaa tcagattgaa 500

 gagcttccaa agcaactttt taactgtcag tctttacaca agctgagttt 550

 gccagacaat gatttaacaa cgttaccagc atccattgca aaccttatta 600

 atctcaggga actggatgtc agcaagaatg gaatacagga gtttccagaa 650

 aatataaaaa attgtaaagt tttgacaatt gtggaggcca gtgtaaaccc 700

 tatttccaag ctccctgatg gattttctca gctgttaaac ctaacccagt 750

 tgtatctgaa tgatgctttt cttgagttct tgccagcaaa ttttggcaga 800

 ttaactaaac tccaaatatt agagcttaga gaaaaccagt taaaaatgtt 850

 gcctaaaact atgaatagac tgacccagct ggaaagattg gatttgggaa 900

 gtaacgaatt cacggaagtg cctgaagtac ttgagcaact aagtggattg 950

 aaagagtttt ggatggatgc taatagactg acttttattc cagggtttat 1000

 tggtagtttg aaacagctca catatttgga tgtttctaaa aataatattg 1050

 aaatggttga agaaggaatt tcaacatgtg aaaaccttca agacctccta 1100

 ttatcaagca attcacttca gcagcttcct gagactattg gttcgttgaa 1150

 gaatataaca acgcttaaaa tagatgaaaa ccagttaatg tatctgccag 1200

 actctatagg agggttaata tcagtagaag aactggattg tagtttcaat 1250

 gaggttgaag ctttgccttc atctattggg cagcttacta acttaagaac 1300

 ttttgctgct gatcataatt acttacagca gttgccccca gagattggaa 1350

 gctggaaaaa tataactgtg ctgtttctcc attccaataa acttgagaca 1400

 cttccagagg aaatgggtga tatgcaaaaa ttaaaagtca ttaatttaag 1450

 tgataataga ttaaagaatt taccctttag ctttacaaag ctacagcaat 1500

 tgacagctat gtggctctca gataatcagt ccaaacccct gatacctctt 1550

 caaaaagaaa ctgattcaga gacccagaaa atggtgctta ccaactacat 1600

 gttccctcaa cagccaagga ctgaggatgt tatgtttata tcagataatg 1650

 aaagttttaa cccttcattg tgggaggaac agaggaaaca gcgggctcaa 1700

 gttgcatttg aatgtgatga agacaaagat gaaagggagg cacctcccag 1750

 ggagggaaat ttaaaaagat atccaacacc atacccagat gagcttaaga 1800

 atatggtcaa aactgttcaa accattgtac atagattaaa agatgaagag 1850

 accaatgaag actcaggaag agatttgaaa ccacatgaag atcaacaaga 1900

 tataaataaa gatgtgggtg tgaagacctc agaaagtact actacagtaa 1950

 aaagcaaagt tgatgaaaga gaaaaatata tgataggaaa ctctgtacag 2000

 aagatcagtg aacctgaagc tgagattagt cctgggagtt taccagtgac 2050

 tgcaaatatg aaagcctctg agaacttgaa gcatattgtt aaccatgatg 2100

 atgtttttga ggaatctgaa gaactttctt ctgatgaaga gatgaaaatg 2150

 gcggagatgc gaccaccatt aattgaaacc tctattaacc agccaaaagt 2200

 cgtagcactt agtaataaca aaaaagatga tacaaaggaa acagattctt 2250

 tatcagatga agttacacac aatagcaatc agaataacag caattgttct 2300

 tctccatctc ggatgtctga ttcagtttct cttaatactg atagtagtca 2350

 agacacctca ctctgctctc cagtgaaaca aactcatatt gatattaatt 2400

 ccaaaatcag gcaagaagat gaaaatttta acagcctttt acaaaatgga 2450

 gatattttaa acagttcaac agaggaaaag ttcaaagctc atgataaaaa 2500

 agattttaac ttacctgaat atgatttgaa tgttgaagag cgattagttc 2550

 taattgagaa aagtgttgac tcaacagcca cagctgatga cactcacaaa 2600

 ttagatcata tcaatatgaa tcttaataaa cttataacta atgatacatt 2650

 tcaaccagag atcatggaaa gatcaaaaac acaggatatt gtgcttggaa 2700

 caagcttttt aagcattaat tctaaagagg aaactgagca cttggaaaat 2750

 ggaaacaagt atcctaattt ggaatccgta aataaggtaa atggacattc 2800

 tgaggaaact tcccagtctc ctaataggac tgaaccacat gacagtgatt 2850

 gttctgttga cttaggtatt tccaaaagca ctgaagatct ctcccctcag 2900

 aaaagtggtc cagttggatc tgttgtgaaa tctcatagca taactaatat 2950

 ggagattgga gggctaaaaa tctatgatat tcttagtgat aatggacctc 3000

 agcagccaag tacaaccgtt aaaatcacat ctgctgttga tggaaaaaat 3050

 atagtcagga gcaagtctgc cacactgttg tatgatcaac cattgcaggt 3100

 atttactggt tcttcctcat cttctgattt aatatcagga acaaaggcaa 3150

 ttttcaagtt tgattcaaat cataatcccg aagagccaaa tataataaga 3200

 ggccccacaa gtggcccaca atctgcacct caaatatatg gtcctccaca 3250

 gtataatatc caatacagta gcagtgctgc agtcaaagac actttgtggc 3300

 actccaaaca aaatccccaa atagaccatg ccagttttcc tcctcagctc 3350

 cttcctagat cagagagcac agaaaatcaa agttatgcta aacattctgc 3400

 caatatgaat ttctctaatc ataacaatgt tcgagctaat actgcatacc 3450

 atttacatca gagacttggc ccagcaagac atggggaaat gtgggccatc 3500

 tcaccaaacg accgacttat tcctgcagta actcgaagta caatccagcg 3550

 acaaagtagt gtgtcctcca cagcctctgt aaatcttggt gatccaggct 3600

 ctacaaggcg ggctcagatt cctgaaggag attatttatc atacagagag 3650

 ttccactcag cgggaagaac tcctccaatg atgccaggat cacagagacc 3700

 cctttctgca cgaacataca gcatagatgg tccaaatgca tcaagacctc 3750

 agagtgctcg accctctatt aatgaaatac cagagagaac tatgtcagtt 3800

 agtgatttca attattcacg gactagtcct tcaaaaagac caaatgcaag 3850

 ggttggttct gagcattctt tattagatcc tccaggaaaa agtaaagttc 3900

 ctcgtgactg gagagaacaa gtacttcgac atattgaagc caaaaagtta 3950

 gaaaagatgc ctttgagtaa tggacagatg ggccagcctc tcaggcctca 4000

 ggcaaattat agtcaaatac atcacccccc tcaggcatct gtggcaaggc 4050

 atccctctag agaacaacta attgattact tgatgctgaa agtggcccac 4100

 cagcctccat atacacagcc ccattgttct cctagacaag gccatgaact 4150

 ggcaaaacaa gagattcgag tgagggttga aaaggatcca gaacttggat 4200

 ttagcatatc aggtggtgtc gggggtagag gaaacccatt cagacctgat 4250

 gatgatggta tatttgtaac aagggtacaa cctgaaggac cagcatcaaa 4300

 attactgcag ccaggtgata aaattattca ggctaatggc tacagtttta 4350

 taaatattga acatggacaa gcagtgtcct tgctaaaaac tttccagaat 4400

 acagttgaac tcatcattgt acgagaagtt tcctcataag cactgtggac 4450

 aaaaaaagcg gggaagacag caagatttat tggaagatac ttacagggga 4500

 aattaatatt ttgactattt ttatatataa agaagaactc aaaaaattat 4550

 gttcaaattt gtacattaat gaaataatgg ataaaggaga ctgttgaatt 4600

 cataccatat aaaacttgtt aggtttttaa acatagcaat caaggctaca 4650

 aaaacaaacc tgtgttgttt ttgtatagat tgtaggttta tttttggatt 4700

 tcatatacat gactgaactg tgtgcaaggc aatagttagc cttgatttta 4750

 gcccagagac agatggcaga gctatctctc tcatagcttt tatgccctta 4800

 tttttattca actggtatta atgtttttct cctgaaacta ctttttttga 4850

 tgtgggcaag agatttgaag tgttggcttt tgctatgtgc atattgaatt 4900

 gaagagtgag taggtgaagg tggtgctggt gggttcactt tccaaggcca 4950

 gactaaaaca gttattttct ataaaaatct ggaagcaaag aatggggatg 5000

 gggagagcta cgtggtagta tgtttttatt aggagaataa tgcaataaaa 5050

 tatgtaatgt cttttttata aagcaaaaaa gacaataatt gcatttatga 5100

 gctcggcagg atctgttctt gtcatagcca ttgactatac atttgctact 5150

 ggtgattcag tttttaattt tttagtcaca ggaaattttt aactctactg 5200

 tagatgcatg tccatgcatt ttctgtgtta tggaaatcca ctgatttttt 5250

 tttttttttc aaatggtggt acttgcaatc tgttttataa ttagtgctcc 5300

 atttaaatct aatttataat ttttatttta agcagcaaat gaaacaaaaa 5350

 tggccagttt taagattgtg ttgcctgtaa cacaaaatgt tacgaaggtt 5400

 taggaaagcc tctttgattt ttgtttggcc ttgcattggc ccttggtaaa 5450

 gtaaaaggaa acagtacact tggagctagg aaaccaaagc aagctttgtg 5500

 aaactggcac agtgatagag aattgctgtg gagagttata gagcaaaggg 5550

 atgggtcctt gaggcctgcc agtgtgtaaa ggtgttcaaa taaagggctg 5600

 tttctacagg taacattaaa tgtgaactca acacttccag agtctttaaa 5650

 gggtttctat gtgtatcagt gtaatagtgt tttaccacca actgcctttc 5700

 tttgttccta gttactgtaa caaatatttg atgatagagg tttattaatt 5750

 ttgtttatcc agaccattaa ttttatttgt ttttgtctat gtaatcaaat 5800

 aaaatttgag taacatgtaa tggtaaggat taatgcatgg ttatttggac 5850

 cagaaaaaag tgccatagaa gaccaataac tgtttagttg aggctagtct 5900

 ggaacctttc attagagcaa tatttggtta ttgcacttca tttttattta 5950

 ctaagaaatg caatttggga atttttaatc tgttatgctt tgtttatcaa 6000

 ccttgatttt aattaagact tttataagac tagcttaaaa caccaaccaa 6050

 cattattttt gcaaaagtga gttggactca ctttccattc ttgctagtca 6100

 gagtaagtag gcagcacttt taaaaatatg tgaactcaaa tattgcactt 6150

 ctttcaagat gttatcaatt ggttattgta ctgtatagtt ttaataattt 6200

 tgattgaaac cctttaacaa ctctttgtaa attttaactc attttagttg 6250

 attttcagta ctatttacat aggaattgat ttttatggat atagtagaag 6300

 aaatgtgctg tattttgata aaattcactt attgtatgtg tgttgtaatc 6350

 taaaaaaaaa aagaatgaca aacagcttct ttaagacaaa aaaaaaaaaa 6400

 aaaaaaaaa 6409

<210> 3111
<211> 1371
<212> PRT
<213> Homo sapien

<400> 3111
 Met Thr Thr Lys Arg Ser Leu Phe Val Arg Leu Val Pro Cys Arg
   1               5                  10                  15

 Cys Leu Arg Gly Glu Glu Glu Thr Val Thr Thr Leu Asp Tyr Ser
                  20                  25                  30

 His Cys Ser Leu Glu Gln Val Pro Lys Glu Ile Phe Thr Phe Glu
                  35                  40                  45

 Lys Thr Leu Glu Glu Leu Tyr Leu Asp Ala Asn Gln Ile Glu Glu
                  50                  55                  60

 Leu Pro Lys Gln Leu Phe Asn Cys Gln Ser Leu His Lys Leu Ser
                  65                  70                  75

 Leu Pro Asp Asn Asp Leu Thr Thr Leu Pro Ala Ser Ile Ala Asn
                  80                  85                  90

 Leu Ile Asn Leu Arg Glu Leu Asp Val Ser Lys Asn Gly Ile Gln
                  95                 100                 105

 Glu Phe Pro Glu Asn Ile Lys Asn Cys Lys Val Leu Thr Ile Val
                 110                 115                 120

 Glu Ala Ser Val Asn Pro Ile Ser Lys Leu Pro Asp Gly Phe Ser
                 125                 130                 135

 Gln Leu Leu Asn Leu Thr Gln Leu Tyr Leu Asn Asp Ala Phe Leu
                 140                 145                 150

 Glu Phe Leu Pro Ala Asn Phe Gly Arg Leu Thr Lys Leu Gln Ile
                 155                 160                 165

 Leu Glu Leu Arg Glu Asn Gln Leu Lys Met Leu Pro Lys Thr Met
                 170                 175                 180

 Asn Arg Leu Thr Gln Leu Glu Arg Leu Asp Leu Gly Ser Asn Glu
                 185                 190                 195

 Phe Thr Glu Val Pro Glu Val Leu Glu Gln Leu Ser Gly Leu Lys
                 200                 205                 210

 Glu Phe Trp Met Asp Ala Asn Arg Leu Thr Phe Ile Pro Gly Phe
                 215                 220                 225

 Ile Gly Ser Leu Lys Gln Leu Thr Tyr Leu Asp Val Ser Lys Asn
                 230                 235                 240

 Asn Ile Glu Met Val Glu Glu Gly Ile Ser Thr Cys Glu Asn Leu
                 245                 250                 255

 Gln Asp Leu Leu Leu Ser Ser Asn Ser Leu Gln Gln Leu Pro Glu
                 260                 265                 270

 Thr Ile Gly Ser Leu Lys Asn Ile Thr Thr Leu Lys Ile Asp Glu
                 275                 280                 285

 Asn Gln Leu Met Tyr Leu Pro Asp Ser Ile Gly Gly Leu Ile Ser
                 290                 295                 300

 Val Glu Glu Leu Asp Cys Ser Phe Asn Glu Val Glu Ala Leu Pro
                 305                 310                 315

 Ser Ser Ile Gly Gln Leu Thr Asn Leu Arg Thr Phe Ala Ala Asp
                 320                 325                 330

 His Asn Tyr Leu Gln Gln Leu Pro Pro Glu Ile Gly Ser Trp Lys
                 335                 340                 345

 Asn Ile Thr Val Leu Phe Leu His Ser Asn Lys Leu Glu Thr Leu
                 350                 355                 360

 Pro Glu Glu Met Gly Asp Met Gln Lys Leu Lys Val Ile Asn Leu
                 365                 370                 375

 Ser Asp Asn Arg Leu Lys Asn Leu Pro Phe Ser Phe Thr Lys Leu
                 380                 385                 390

 Gln Gln Leu Thr Ala Met Trp Leu Ser Asp Asn Gln Ser Lys Pro
                 395                 400                 405

 Leu Ile Pro Leu Gln Lys Glu Thr Asp Ser Glu Thr Gln Lys Met
                 410                 415                 420

 Val Leu Thr Asn Tyr Met Phe Pro Gln Gln Pro Arg Thr Glu Asp
                 425                 430                 435

 Val Met Phe Ile Ser Asp Asn Glu Ser Phe Asn Pro Ser Leu Trp
                 440                 445                 450

 Glu Glu Gln Arg Lys Gln Arg Ala Gln Val Ala Phe Glu Cys Asp
                 455                 460                 465

 Glu Asp Lys Asp Glu Arg Glu Ala Pro Pro Arg Glu Gly Asn Leu
                 470                 475                 480

 Lys Arg Tyr Pro Thr Pro Tyr Pro Asp Glu Leu Lys Asn Met Val
                 485                 490                 495

 Lys Thr Val Gln Thr Ile Val His Arg Leu Lys Asp Glu Glu Thr
                 500                 505                 510

 Asn Glu Asp Ser Gly Arg Asp Leu Lys Pro His Glu Asp Gln Gln
                 515                 520                 525

 Asp Ile Asn Lys Asp Val Gly Val Lys Thr Ser Glu Ser Thr Thr
                 530                 535                 540

 Thr Val Lys Ser Lys Val Asp Glu Arg Glu Lys Tyr Met Ile Gly
                 545                 550                 555

 Asn Ser Val Gln Lys Ile Ser Glu Pro Glu Ala Glu Ile Ser Pro
                 560                 565                 570

 Gly Ser Leu Pro Val Thr Ala Asn Met Lys Ala Ser Glu Asn Leu
                 575                 580                 585

 Lys His Ile Val Asn His Asp Asp Val Phe Glu Glu Ser Glu Glu
                 590                 595                 600

 Leu Ser Ser Asp Glu Glu Met Lys Met Ala Glu Met Arg Pro Pro
                 605                 610                 615

 Leu Ile Glu Thr Ser Ile Asn Gln Pro Lys Val Val Ala Leu Ser
                 620                 625                 630

 Asn Asn Lys Lys Asp Asp Thr Lys Glu Thr Asp Ser Leu Ser Asp
                 635                 640                 645

 Glu Val Thr His Asn Ser Asn Gln Asn Asn Ser Asn Cys Ser Ser
                 650                 655                 660

 Pro Ser Arg Met Ser Asp Ser Val Ser Leu Asn Thr Asp Ser Ser
                 665                 670                 675

 Gln Asp Thr Ser Leu Cys Ser Pro Val Lys Gln Thr His Ile Asp
                 680                 685                 690

 Ile Asn Ser Lys Ile Arg Gln Glu Asp Glu Asn Phe Asn Ser Leu
                 695                 700                 705

 Leu Gln Asn Gly Asp Ile Leu Asn Ser Ser Thr Glu Glu Lys Phe
                 710                 715                 720

 Lys Ala His Asp Lys Lys Asp Phe Asn Leu Pro Glu Tyr Asp Leu
                 725                 730                 735

 Asn Val Glu Glu Arg Leu Val Leu Ile Glu Lys Ser Val Asp Ser
                 740                 745                 750

 Thr Ala Thr Ala Asp Asp Thr His Lys Leu Asp His Ile Asn Met
                 755                 760                 765

 Asn Leu Asn Lys Leu Ile Thr Asn Asp Thr Phe Gln Pro Glu Ile
                 770                 775                 780

 Met Glu Arg Ser Lys Thr Gln Asp Ile Val Leu Gly Thr Ser Phe
                 785                 790                 795

 Leu Ser Ile Asn Ser Lys Glu Glu Thr Glu His Leu Glu Asn Gly
                 800                 805                 810

 Asn Lys Tyr Pro Asn Leu Glu Ser Val Asn Lys Val Asn Gly His
                 815                 820                 825

 Ser Glu Glu Thr Ser Gln Ser Pro Asn Arg Thr Glu Pro His Asp
                 830                 835                 840

 Ser Asp Cys Ser Val Asp Leu Gly Ile Ser Lys Ser Thr Glu Asp
                 845                 850                 855

 Leu Ser Pro Gln Lys Ser Gly Pro Val Gly Ser Val Val Lys Ser
                 860                 865                 870

 His Ser Ile Thr Asn Met Glu Ile Gly Gly Leu Lys Ile Tyr Asp
                 875                 880                 885

 Ile Leu Ser Asp Asn Gly Pro Gln Gln Pro Ser Thr Thr Val Lys
                 890                 895                 900

 Ile Thr Ser Ala Val Asp Gly Lys Asn Ile Val Arg Ser Lys Ser
                 905                 910                 915

 Ala Thr Leu Leu Tyr Asp Gln Pro Leu Gln Val Phe Thr Gly Ser
                 920                 925                 930

 Ser Ser Ser Ser Asp Leu Ile Ser Gly Thr Lys Ala Ile Phe Lys
                 935                 940                 945

 Phe Asp Ser Asn His Asn Pro Glu Glu Pro Asn Ile Ile Arg Gly
                 950                 955                 960

 Pro Thr Ser Gly Pro Gln Ser Ala Pro Gln Ile Tyr Gly Pro Pro
                 965                 970                 975

 Gln Tyr Asn Ile Gln Tyr Ser Ser Ser Ala Ala Val Lys Asp Thr
                 980                 985                 990

 Leu Trp His Ser Lys Gln Asn Pro Gln Ile Asp His Ala Ser Phe
                 995                1000                1005

 Pro Pro Gln Leu Leu Pro Arg Ser Glu Ser Thr Glu Asn Gln Ser
                1010                1015                1020

 Tyr Ala Lys His Ser Ala Asn Met Asn Phe Ser Asn His Asn Asn
                1025                1030                1035

 Val Arg Ala Asn Thr Ala Tyr His Leu His Gln Arg Leu Gly Pro
                1040                1045                1050

 Ala Arg His Gly Glu Met Trp Ala Ile Ser Pro Asn Asp Arg Leu
                1055                1060                1065

 Ile Pro Ala Val Thr Arg Ser Thr Ile Gln Arg Gln Ser Ser Val
                1070                1075                1080

 Ser Ser Thr Ala Ser Val Asn Leu Gly Asp Pro Gly Ser Thr Arg
                1085                1090                1095

 Arg Ala Gln Ile Pro Glu Gly Asp Tyr Leu Ser Tyr Arg Glu Phe
                1100                1105                1110

 His Ser Ala Gly Arg Thr Pro Pro Met Met Pro Gly Ser Gln Arg
                1115                1120                1125

 Pro Leu Ser Ala Arg Thr Tyr Ser Ile Asp Gly Pro Asn Ala Ser
                1130                1135                1140

 Arg Pro Gln Ser Ala Arg Pro Ser Ile Asn Glu Ile Pro Glu Arg
                1145                1150                1155

 Thr Met Ser Val Ser Asp Phe Asn Tyr Ser Arg Thr Ser Pro Ser
                1160                1165                1170

 Lys Arg Pro Asn Ala Arg Val Gly Ser Glu His Ser Leu Leu Asp
                1175                1180                1185

 Pro Pro Gly Lys Ser Lys Val Pro Arg Asp Trp Arg Glu Gln Val
                1190                1195                1200

 Leu Arg His Ile Glu Ala Lys Lys Leu Glu Lys Met Pro Leu Ser
                1205                1210                1215

 Asn Gly Gln Met Gly Gln Pro Leu Arg Pro Gln Ala Asn Tyr Ser
                1220                1225                1230

 Gln Ile His His Pro Pro Gln Ala Ser Val Ala Arg His Pro Ser
                1235                1240                1245

 Arg Glu Gln Leu Ile Asp Tyr Leu Met Leu Lys Val Ala His Gln
                1250                1255                1260

 Pro Pro Tyr Thr Gln Pro His Cys Ser Pro Arg Gln Gly His Glu
                1265                1270                1275

 Leu Ala Lys Gln Glu Ile Arg Val Arg Val Glu Lys Asp Pro Glu
                1280                1285                1290

 Leu Gly Phe Ser Ile Ser Gly Gly Val Gly Gly Arg Gly Asn Pro
                1295                1300                1305

 Phe Arg Pro Asp Asp Asp Gly Ile Phe Val Thr Arg Val Gln Pro
                1310                1315                1320

 Glu Gly Pro Ala Ser Lys Leu Leu Gln Pro Gly Asp Lys Ile Ile
                1325                1330                1335

 Gln Ala Asn Gly Tyr Ser Phe Ile Asn Ile Glu His Gly Gln Ala
                1340                1345                1350

 Val Ser Leu Leu Lys Thr Phe Gln Asn Thr Val Glu Leu Ile Ile
                1355                1360                1365

 Val Arg Glu Val Ser Ser
                1370

<210> 3112
<211> 1125
<212> DNA
<213> Homo sapien

<400> 3112
 ggcacgagga agcgaccgag ggactgggag tcgttagtga gagtttcact 50

 cttgttgcct aggctggagt gcaatggtgc gatcttggct catcacgacc 100

 ttcgcctccc aggttcaagt gattgtccca tttcagcctc ccgagtagct 150

 gggattacag gatgacgcgg catggcaaga actgcaccgc aggggccgtc 200

 tacacctacc acgagaagaa gaaggacaca gcggcctcgg gctatgggac 250

 ccagaacatt cgactgagcc gggatgccgt gaaggacttc gactgctgtt 300

 gtctctccct gcagccttgc cacgatcctg ttgtcacccc agatggctac 350

 ctgtatgagc gtgaggccat cctggagtac attctgcacc agaagaagga 400

 gattgcccgg cagatgaagg cctacgagaa gcagcggggc acccggcgcg 450

 aggagcagaa ggagcttcag cgggcggcct cgcaggacca tgtgcggggc 500

 ttcctggaga aggagtcggc tatcgtgagc cggcccctca accctttcac 550

 agccaaggcc ctctcgggca ccagcccaga tgatgtccaa cctgggccca 600

 gtgtgggtcc tccaagtaag gacaaggaca aagtgctgcc cagcttctgg 650

 atcccgtcgc tgacgcccga agccaaggcc accaagctgg agaagccgtc 700

 ccgcacggtg acctgcccca tgtcagggaa gcccctgcgc atgtcggacc 750

 tgacgcccgt gcacttcaca ccgctagaca gctccgtgga ccgcgtgggg 800

 ctcatcaccc gcagcgagcg ctacgtgtgt gccgtgaccc gcgacagcct 850

 gagcaacgcc accccctgcg ctgtgctgcg gccctctggg gctgtggtca 900

 ccctcgaatg cgtggagaag ctgattcgga aggacatggt ggaccctgtg 950

 actggagaca aactcacaga ccgcgacatc atcgtgctgc agcggggcgg 1000

 taccggcttc gcgggctccg gagtgaagct gcaagcggag aaatcacggc 1050

 cggtgatgca ggcctgagtg tgtgcgggag accaaataaa ccggcttggg 1100

 tgcgcaaaaa aaaaaaaaaa aaaaa 1125

<210> 3113
<211> 301
<212> PRT
<213> Homo sapien

<400> 3113
 Met Thr Arg His Gly Lys Asn Cys Thr Ala Gly Ala Val Tyr Thr
   1               5                  10                  15

 Tyr His Glu Lys Lys Lys Asp Thr Ala Ala Ser Gly Tyr Gly Thr
                  20                  25                  30

 Gln Asn Ile Arg Leu Ser Arg Asp Ala Val Lys Asp Phe Asp Cys
                  35                  40                  45

 Cys Cys Leu Ser Leu Gln Pro Cys His Asp Pro Val Val Thr Pro
                  50                  55                  60

 Asp Gly Tyr Leu Tyr Glu Arg Glu Ala Ile Leu Glu Tyr Ile Leu
                  65                  70                  75

 His Gln Lys Lys Glu Ile Ala Arg Gln Met Lys Ala Tyr Glu Lys
                  80                  85                  90

 Gln Arg Gly Thr Arg Arg Glu Glu Gln Lys Glu Leu Gln Arg Ala
                  95                 100                 105

 Ala Ser Gln Asp His Val Arg Gly Phe Leu Glu Lys Glu Ser Ala
                 110                 115                 120

 Ile Val Ser Arg Pro Leu Asn Pro Phe Thr Ala Lys Ala Leu Ser
                 125                 130                 135

 Gly Thr Ser Pro Asp Asp Val Gln Pro Gly Pro Ser Val Gly Pro
                 140                 145                 150

 Pro Ser Lys Asp Lys Asp Lys Val Leu Pro Ser Phe Trp Ile Pro
                 155                 160                 165

 Ser Leu Thr Pro Glu Ala Lys Ala Thr Lys Leu Glu Lys Pro Ser
                 170                 175                 180

 Arg Thr Val Thr Cys Pro Met Ser Gly Lys Pro Leu Arg Met Ser
                 185                 190                 195

 Asp Leu Thr Pro Val His Phe Thr Pro Leu Asp Ser Ser Val Asp
                 200                 205                 210

 Arg Val Gly Leu Ile Thr Arg Ser Glu Arg Tyr Val Cys Ala Val
                 215                 220                 225

 Thr Arg Asp Ser Leu Ser Asn Ala Thr Pro Cys Ala Val Leu Arg
                 230                 235                 240

 Pro Ser Gly Ala Val Val Thr Leu Glu Cys Val Glu Lys Leu Ile
                 245                 250                 255

 Arg Lys Asp Met Val Asp Pro Val Thr Gly Asp Lys Leu Thr Asp
                 260                 265                 270

 Arg Asp Ile Ile Val Leu Gln Arg Gly Gly Thr Gly Phe Ala Gly
                 275                 280                 285

 Ser Gly Val Lys Leu Gln Ala Glu Lys Ser Arg Pro Val Met Gln
                 290                 295                 300

 Ala


<210> 3114
<211> 1278
<212> DNA
<213> Homo sapien

<400> 3114
 acaggggaaa taccgcggcg ccggtagttg ctgtggtttc cgttctgagc 50

 tcgcagctta ggagctgaag atcgcggact tagcgttgcc gcgtccgagt 100

 ccggccatca gtggctgcag atccggagcc aggagctcaa ccacccttct 150

 tcggaacagg gccggcctgc tgctgtgccc tcgacgctcg gtgcctgtat 200

 ctactccggg gcctaggtcg gctccggggg cggcttagga gaaggccgcc 250

 ggcgagatgt tcaaaaacac gttccagagc ggcttcctct ccatcctcta 300

 cagcatcggc agcaagcctc tgcaaatctg ggacaaaaag gtacggaatg 350

 gccacatcaa aagaatcact gataatgaca tccagtccct ggtgctagag 400

 attgaaggga caaatgtaag caccacatat atcacatgcc ctgcagaccc 450

 caagaagacg ctgggaatta aacttccttt ccttgtcatg attatcaaaa 500

 acctgaagaa gtattttacc ttcgaagtgc aggtactaga tgacaagaat 550

 gtgcgtcgtc gctttcgggc aagtaactac cagagcacca cccgggtcaa 600

 acccttcatc tgcaccatgc ccatgcggct ggatgacggc tggaaccaga 650

 ttcagttcaa cttgctagac ttcacacggc gagcatacgg caccaattac 700

 atcgagaccc tcagagtgca gatccatgca aattgtcgca tccgacgggt 750

 ttacttctca gacagactct actcagaaga tgagctgccg gcagagttca 800

 aactgtatct cccagttcag aacaaggcaa agcaataact ggaattgtga 850

 ctcgagggat agacccctgg atgtgactct tctttttaaa aggaaactat 900

 gtggaggacg atgcaaaaac atatttatct tagtttgctc tgctgtagtt 950

 ctgttattta tacttggtgt tgcttgtcat ggacaccggt gaacatgccg 1000

 taactctgtg actgcattgt aagtgcagtg ggggtaagca gtcctgtgag 1050

 tggcgcatga acgctggagc ttattccgcc gcctgcccca gtgtgggggg 1100

 agataccttt accatgaact tacagaatta aagatggccc ataaggaatt 1150

 ccagaccaat atttcttcct gcggtttatt ctatgtttta tatattatct 1200

 aaatatatgt atatgctgtg tcatactcat aatctggaaa tgaataaagt 1250

 gatatattcc tggtttgtaa aaaaaaaa 1278

<210> 3115
<211> 193
<212> PRT
<213> Homo sapien

<400> 3115
 Met Phe Lys Asn Thr Phe Gln Ser Gly Phe Leu Ser Ile Leu Tyr
   1               5                  10                  15

 Ser Ile Gly Ser Lys Pro Leu Gln Ile Trp Asp Lys Lys Val Arg
                  20                  25                  30

 Asn Gly His Ile Lys Arg Ile Thr Asp Asn Asp Ile Gln Ser Leu
                  35                  40                  45

 Val Leu Glu Ile Glu Gly Thr Asn Val Ser Thr Thr Tyr Ile Thr
                  50                  55                  60

 Cys Pro Ala Asp Pro Lys Lys Thr Leu Gly Ile Lys Leu Pro Phe
                  65                  70                  75

 Leu Val Met Ile Ile Lys Asn Leu Lys Lys Tyr Phe Thr Phe Glu
                  80                  85                  90

 Val Gln Val Leu Asp Asp Lys Asn Val Arg Arg Arg Phe Arg Ala
                  95                 100                 105

 Ser Asn Tyr Gln Ser Thr Thr Arg Val Lys Pro Phe Ile Cys Thr
                 110                 115                 120

 Met Pro Met Arg Leu Asp Asp Gly Trp Asn Gln Ile Gln Phe Asn
                 125                 130                 135

 Leu Leu Asp Phe Thr Arg Arg Ala Tyr Gly Thr Asn Tyr Ile Glu
                 140                 145                 150

 Thr Leu Arg Val Gln Ile His Ala Asn Cys Arg Ile Arg Arg Val
                 155                 160                 165

 Tyr Phe Ser Asp Arg Leu Tyr Ser Glu Asp Glu Leu Pro Ala Glu
                 170                 175                 180

 Phe Lys Leu Tyr Leu Pro Val Gln Asn Lys Ala Lys Gln
                 185                 190

<210> 3116
<211> 6919
<212> DNA
<213> Homo sapien

<400> 3116
 cccacggatc atcagaaggc gcggacctgg aggaggcgcc ccagaaggcg 50

 acgcctcttg cctcctgtct ctcgcctctc gaaggaagtt tgctcttaat 100

 ttcagagccg ggttcgccgt cggatcaacc tccaggagct agcagcgggc 150

 gcggaccggg cagtttccgc gctcagcaca ggcagctcgc ggtcatgggc 200

 ggctcagcct ccagccagct ggacgagggc aagtgcgctt acatccgagg 250

 gaaaactgag gctgccatca aaaacttcag tccctactac agtcgtcagt 300

 actctgtggc tttctgcaat cacgtgcgca ctgaagtaga acagcaaaga 350

 gatttaacgt cacagttttt gaagaccaag ccaccattgg cgcctggaac 400

 tattttgtat gaagcagagc tatcacaatt ttctgaagac ataaagaagt 450

 ggaaggagag atacgttgta gttaaaaatg attatgctgt ggagagctat 500

 gagaataaag aggcctatca gagaggagct gctcctaaat gtcgaattct 550

 tccagccggt ggcaaggtgt taacctcaga agatgaatat aatctgttgt 600

 ctgacaggca tttcccagac cctcttgcct ccagtgagaa ggagaacact 650

 cagccctttg tggtcctgcc caaggaattc ccagtgtacc tgtggcagcc 700

 cttcttcaga cacggctact tctgcttcca cgaggctgct gaccagaaga 750

 ggtttagtgc cctcctgagt gactgcgtca ggcatctcaa tcatgattac 800

 atgaagcaga tgacatttga agcccaagcc tttttagaag ctgtgcaatt 850

 cttccgacag gagaagggtc actatggttc ctgggaaatg atcactgggg 900

 atgaaatcca gatcctgagt aacctggtga tggaggagct cctgcccact 950

 cttcagacag acctgctgcc taagatgaag gggaagaaga atgacagaaa 1000

 gaggacgtgg cttggtctcc tcgaggaggc ctacaccctg gttcagcatc 1050

 aagtttcaga aggattaagt gccttgaagg aggaatgcag agctctgaca 1100

 aagggcctgg aaggaacgat ccgttctgac atggatcaga ttgtgaactc 1150

 aaagaactat ttaattggaa agatcaaagc gatggtggcc cagccggcgg 1200

 agaaaagctg cttggagagt gtgcagccat tcctggcatc catcctggag 1250

 gagctcatgg gaccagtgag ctcgggattc agtgaagtac gtgtactctt 1300

 tgagaaagag gtgaatgaag tcagccagaa cttccagacc accaaagaca 1350

 gtgtccagct aaaggagcat ctagaccggc ttatgaatct tccgctgcat 1400

 tccgtgaaga tggaaccttg ttatactaaa gtcaacctgc ttcacgagcg 1450

 cctgcaggat ctcaagagcc gcttcagatt cccccacatt gatctggtgg 1500

 ttcagaggac acagaactac atgcaggagc taatggagaa tgcagtgttc 1550

 acttttgagc agttgctttc cccacatctc caaggagagg cctccaaaac 1600

 tgcagttgcc attgagaagg ttaaactccg agtcttaaag caatatgatt 1650

 atgacagcag caccatccga aagaagatat ttcaagaggc actagttcaa 1700

 atcacacttc ccactgtgca gaaggcactg gcgtccacat gcaaaccaga 1750

 gcttcagaaa tacgagcagt tcatctttgc agatcatacc aatatgattc 1800

 acgttgaaaa tgtctatgag gagattttac atcagatcct gcttgatgaa 1850

 actctgaaag tgataaagga agctgctatc ttgaagaaac acaacttatt 1900

 tgaagataac atggccttgc ccagtgaaag tgtgtccagc ttaacagatc 1950

 taaagccccc cacagggtca aaccaggcca gccctgccag gagagcttct 2000

 gccattctgc caggagttct gggtagtgag accctcagta acgaagtatt 2050

 ccaggagtca gaggaagaga agcagcctga ggtccctagc tcgttggcca 2100

 aaggagaaag cctttctctc cctgggccaa gcccaccccc agatgggact 2150

 gagcaggtga ttatttcaag agtggatgac cccgtggtga atcctgtggc 2200

 aacagaggac acagcaggac tcccgggcac atgctcatca gagctggagt 2250

 ttggagggac ccttgaggat gaagaacccg cccaggaaga gccagaaccc 2300

 atcactgcct cgggttcttt gaaggcgctc agaaagttgc tgacagcgtc 2350

 cgtggaagta ccagtggact ctgctccagt gatggaagaa gatacgaatg 2400

 gggagagcca cgttccccaa gaaaatgaag aagaagagga aaaagagccc 2450

 agtcaggcag ctgccatcca ccccgacaac tgtgaagaaa gtgaagtcag 2500

 cgagagggag gcccaacctc cctgtcccga ggcccatggg gaggagttgg 2550

 ggggatttcc agaggtaggc agcccagcct ctccgccagc cagtggaggg 2600

 ctcaccgagg agcccctggg gcccatggag ggggagctcc caggagaggc 2650

 ctgcacactc actgcccatg aaggaagagg gggcaagtgt accgaggaag 2700

 gggatgcctc acagcaagag ggctgcacct taggttctga ccccatctgc 2750

 ctcagtgaga gccaggtttc tgaggaacaa gaagagatgg gagggcaaag 2800

 cagcgcggcc caggccacgg ccagtgtgaa tgcagaggag atcaaggtag 2850

 cccgtattca tgagtgtcag tgggtggtgg aggatgctcc aaacccggat 2900

 gtcctgctgt cacacaaaga tgacgtgaag gagggagaag gtggtcagga 2950

 gagtttccca gagctgccct cagaggagtg aaagggacaa tttggctgaa 3000

 gtctttctct gaaaaaagcc aaagcgttat aggggtacac ttaggggttg 3050

 catgcaagct gttaccaaaa aatttttaag tattttctta atttgaataa 3100

 taaaaccaga ggaaatgcat acagggcatg agcaactgag gcaaaccttt 3150

 gtggacatga attgttctac gatgaatttt tgctttagta ttttaataag 3200

 aattacaaag acaatggcat acttggggtg agagggagct gaggatgtct 3250

 gaggagggaa tagtattgca gggaagactg agaaaacagt aggatgacag 3300

 ttttgagtat actctgcact tttcaattgt gcaatcttct tgtgcacttt 3350

 aaggcttttt aattttgttt gagaatgcaa atgtatactg taagtctacc 3400

 tttactatct actatgccta cttcaccatc tcttaaggac tcggcatttg 3450

 tccacagtca gactgcaaga gagggtaggt catgaacagt cacccgtgct 3500

 ggctgtagcc cccacagagg caatcatgcc caatagattc aagagaagct 3550

 aagcggaaat ggagggtgga aggtgtgatc tgtgggactg tctgggcctg 3600

 ttactcatcc tgctatcaat ttcttattaa ttaatcttga tgattcttat 3650

 taattaatca catttgcagg aaattcagat gaggcaagaa aattttattg 3700

 gcctgggtaa gactgaaagc attccaaatt aggcttagac tgtgcaaagg 3750

 gcttagctaa gttatcgagc ttaaaacccg tcaattaaac aaacattatt 3800

 tgaacagtta ctgcatgcca cgcactgtgt tgggcttagt aataaaaaaa 3850

 agaaaagata agtgcttgtt ctagcataaa ttaaaaggtc caagggaatt 3900

 taatctggaa gagaacatat gccaattttt aaactatgac agcttttttt 3950

 tctctttcca ttcaaatagt cctggttcat tcccagaagg gcacaaaatg 4000

 aatgaataaa taaataaatg aataaagaca aaagccaagg tgtatgctct 4050

 caagttccaa agatgttatc aaamgctgaa atcatttgtt tggtcattca 4100

 gcaagctaat tgagtctctg ttatatacca agcactgggg ataccatggc 4150

 gaaaaacaac tttgttcctt cctcctagaa cttacatttt aatggaaata 4200

 gacaaaacac atcttcttaa cggatggtga cctataacca ttaatgttga 4250

 aaatggaaga gacttgcttc caaaagatta aaaggagttg ttcttttctc 4300

 cttcagaaaa ataccagatc atttcctaaa atctccagtc ccaagtatta 4350

 catcgtggtt tccctccccg actttttatt ttattttatt ctattttttt 4400

 gagatggagt ctcgctctgt cgccaaggct ggagtgcagt ggtgtgatct 4450

 cggctcactg caacctccgc ctcctgggtt caggagattc tcctctgtca 4500

 gcgtcccaag tagctggaat tacagccatg cggcaccatt cccggctaat 4550

 ttttgtattt ttggtggaga tgggttttca ccatgttggc caggctggtc 4600

 tcraactcct gatttcaggc gatccaccca cctcgacttc ccaaagtgct 4650

 gggattacag cgtgagctac ctggcccctc cccaaatttt aacatcagat 4700

 ctcaacatat ttgttgagaa cttgtttaga tcatcactat cgagtaaatt 4750

 tatgtcagtt ctttagagca tttgcttcac acacagttca accatttaac 4800

 cagaaattaa aatatcaccc ttttcagccc tcccatgaag aatttctagg 4850

 tcataaacat gaataatact cagtatatgt ataatatcat atttaattgt 4900

 tgcaactttt cttggcgtgt ttaaatcctc atgtctttga gggatcccac 4950

 cacaggtgaa ggaagtaaag accacttctc ccccagtctc tgctttctgc 5000

 agtgctcact catatcctgg catttagcat ggtgtgttga aattaggttt 5050

 acttcttgtc tctccaagtg gctcctctct taaaagacag aaactagggt 5100

 ttagtcatca tttgtgcttc ctgctagaaa cccacagcct tgaataatgg 5150

 cttcctgcct ccttgagtca ctttaatatc cctggtgcat aggacctggc 5200

 atgcgtcagg ctgctcggga aatgtgggaa ctggacaccc agaacactgc 5250

 tgtgctgggg ctatttgggg cctgctgtca ggcagaaaga cgttttgaat 5300

 tgggctttct gcccttgttg agttttctct taagtaaagt ccaaagtcca 5350

 aggggcagat ggccagatgc actgcccagt aaggcaggaa gccaaagagg 5400

 cagtgccagc cccacaaagg ctgcccgact ccctgggaca gtagtgtgga 5450

 gtcccagccc aggctgacct cacaccggag cttcctagct tcctttcttt 5500

 gctcaatgca gggcttcttg caccccctgg aaagctaaga gatttttttc 5550

 aaccctaaaa gagagtacct ttcactgcat tggatggatg aacatcagtg 5600

 ccctaacttt atccatcatg taggtcaggg aggactgggc actatttggc 5650

 aggatgtact ccagaatata atcaaagaat tttctgtaca tatttcacta 5700

 aagacaagtt tttgggctgg atgtggtagc ttacacctat aatcccagca 5750

 ctttgggagg ctgaggtgag agggtcactt gagcccagga gttctagaca 5800

 agcctgggaa acatagcaag atctcatcct tacaaaaaat aataatggtg 5850

 tgtgcctgca gtcctagcta cttgggtggt tgaggcagga ggattgtttg 5900

 agcgagggaa gttgaggctg cagtgaacta tgattttacc actgcactcc 5950

 agcttgggcg acggagtgag accctgtctc aaaaaaaaaa aaagttttct 6000

 agaataagca ggatgattgt ttaatttgaa gatggaacag gaaactagag 6050

 tgcatttaaa atactctgtc ttcattttaa catgttgaat ggaataactg 6100

 catatcacca tgagtttgtt ttgcttttca tacagacttg tatgtgtcat 6150

 ttgagtggtt tccagattgg agcgaggtta ttctgatcta aatgaacagc 6200

 atttttttcc ttagcctctg tttgccactc tgggtatcgt ctcctatggc 6250

 aaagccatta gaaatgcata aaacctcgag acatggtttt tggcaaaaac 6300

 tccatgactt taaactagct cttttactac tgacctttca cagagaaaaa 6350

 atatttccct tgaaaaaaac tgggcttgtc attttttccc ttgtagcttt 6400

 aagcagagac ataagtgcct tgcattacac atagtaaact ttctttaaaa 6450

 aaaaaaaaaa aagattttgg agactaccag ggtaagattc caacttgtcc 6500

 aaaagctttc tggccttaca tattttatta taaaaattct caagtctggt 6550

 aatcttctat gtcagagcta gtgatttcaa aaggtttcac aattccccaa 6600

 gacaaaagtg attttcgttc attataataa ggttaagtga tatgtgattc 6650

 ataacaattt tgatgtgaag aagggaagga catcattgac ttaataatag 6700

 tatcagtcgg tgcaacagtt ggcaacatgt gccttcacac tttaccataa 6750

 agagacgggt ttgagggttt gccttctaaa gtctgcaact tcaagaaaaa 6800

 aaatcgacac tgtggattga ctttcccggt cactatataa agcaaataaa 6850

 cttaaaacac tttgtaacca tgtatttact ctgccaggtg cctatattcc 6900

 aataaaatgt tcatccttg 6919

<210> 3117
<211> 928
<212> PRT
<213> Homo sapien

<400> 3117
 Met Gly Gly Ser Ala Ser Ser Gln Leu Asp Glu Gly Lys Cys Ala
   1               5                  10                  15

 Tyr Ile Arg Gly Lys Thr Glu Ala Ala Ile Lys Asn Phe Ser Pro
                  20                  25                  30

 Tyr Tyr Ser Arg Gln Tyr Ser Val Ala Phe Cys Asn His Val Arg
                  35                  40                  45

 Thr Glu Val Glu Gln Gln Arg Asp Leu Thr Ser Gln Phe Leu Lys
                  50                  55                  60

 Thr Lys Pro Pro Leu Ala Pro Gly Thr Ile Leu Tyr Glu Ala Glu
                  65                  70                  75

 Leu Ser Gln Phe Ser Glu Asp Ile Lys Lys Trp Lys Glu Arg Tyr
                  80                  85                  90

 Val Val Val Lys Asn Asp Tyr Ala Val Glu Ser Tyr Glu Asn Lys
                  95                 100                 105

 Glu Ala Tyr Gln Arg Gly Ala Ala Pro Lys Cys Arg Ile Leu Pro
                 110                 115                 120

 Ala Gly Gly Lys Val Leu Thr Ser Glu Asp Glu Tyr Asn Leu Leu
                 125                 130                 135

 Ser Asp Arg His Phe Pro Asp Pro Leu Ala Ser Ser Glu Lys Glu
                 140                 145                 150

 Asn Thr Gln Pro Phe Val Val Leu Pro Lys Glu Phe Pro Val Tyr
                 155                 160                 165

 Leu Trp Gln Pro Phe Phe Arg His Gly Tyr Phe Cys Phe His Glu
                 170                 175                 180

 Ala Ala Asp Gln Lys Arg Phe Ser Ala Leu Leu Ser Asp Cys Val
                 185                 190                 195

 Arg His Leu Asn His Asp Tyr Met Lys Gln Met Thr Phe Glu Ala
                 200                 205                 210

 Gln Ala Phe Leu Glu Ala Val Gln Phe Phe Arg Gln Glu Lys Gly
                 215                 220                 225

 His Tyr Gly Ser Trp Glu Met Ile Thr Gly Asp Glu Ile Gln Ile
                 230                 235                 240

 Leu Ser Asn Leu Val Met Glu Glu Leu Leu Pro Thr Leu Gln Thr
                 245                 250                 255

 Asp Leu Leu Pro Lys Met Lys Gly Lys Lys Asn Asp Arg Lys Arg
                 260                 265                 270

 Thr Trp Leu Gly Leu Leu Glu Glu Ala Tyr Thr Leu Val Gln His
                 275                 280                 285

 Gln Val Ser Glu Gly Leu Ser Ala Leu Lys Glu Glu Cys Arg Ala
                 290                 295                 300

 Leu Thr Lys Gly Leu Glu Gly Thr Ile Arg Ser Asp Met Asp Gln
                 305                 310                 315

 Ile Val Asn Ser Lys Asn Tyr Leu Ile Gly Lys Ile Lys Ala Met
                 320                 325                 330

 Val Ala Gln Pro Ala Glu Lys Ser Cys Leu Glu Ser Val Gln Pro
                 335                 340                 345

 Phe Leu Ala Ser Ile Leu Glu Glu Leu Met Gly Pro Val Ser Ser
                 350                 355                 360

 Gly Phe Ser Glu Val Arg Val Leu Phe Glu Lys Glu Val Asn Glu
                 365                 370                 375

 Val Ser Gln Asn Phe Gln Thr Thr Lys Asp Ser Val Gln Leu Lys
                 380                 385                 390

 Glu His Leu Asp Arg Leu Met Asn Leu Pro Leu His Ser Val Lys
                 395                 400                 405

 Met Glu Pro Cys Tyr Thr Lys Val Asn Leu Leu His Glu Arg Leu
                 410                 415                 420

 Gln Asp Leu Lys Ser Arg Phe Arg Phe Pro His Ile Asp Leu Val
                 425                 430                 435

 Val Gln Arg Thr Gln Asn Tyr Met Gln Glu Leu Met Glu Asn Ala
                 440                 445                 450

 Val Phe Thr Phe Glu Gln Leu Leu Ser Pro His Leu Gln Gly Glu
                 455                 460                 465

 Ala Ser Lys Thr Ala Val Ala Ile Glu Lys Val Lys Leu Arg Val
                 470                 475                 480

 Leu Lys Gln Tyr Asp Tyr Asp Ser Ser Thr Ile Arg Lys Lys Ile
                 485                 490                 495

 Phe Gln Glu Ala Leu Val Gln Ile Thr Leu Pro Thr Val Gln Lys
                 500                 505                 510

 Ala Leu Ala Ser Thr Cys Lys Pro Glu Leu Gln Lys Tyr Glu Gln
                 515                 520                 525

 Phe Ile Phe Ala Asp His Thr Asn Met Ile His Val Glu Asn Val
                 530                 535                 540

 Tyr Glu Glu Ile Leu His Gln Ile Leu Leu Asp Glu Thr Leu Lys
                 545                 550                 555

 Val Ile Lys Glu Ala Ala Ile Leu Lys Lys His Asn Leu Phe Glu
                 560                 565                 570

 Asp Asn Met Ala Leu Pro Ser Glu Ser Val Ser Ser Leu Thr Asp
                 575                 580                 585

 Leu Lys Pro Pro Thr Gly Ser Asn Gln Ala Ser Pro Ala Arg Arg
                 590                 595                 600

 Ala Ser Ala Ile Leu Pro Gly Val Leu Gly Ser Glu Thr Leu Ser
                 605                 610                 615

 Asn Glu Val Phe Gln Glu Ser Glu Glu Glu Lys Gln Pro Glu Val
                 620                 625                 630

 Pro Ser Ser Leu Ala Lys Gly Glu Ser Leu Ser Leu Pro Gly Pro
                 635                 640                 645

 Ser Pro Pro Pro Asp Gly Thr Glu Gln Val Ile Ile Ser Arg Val
                 650                 655                 660

 Asp Asp Pro Val Val Asn Pro Val Ala Thr Glu Asp Thr Ala Gly
                 665                 670                 675

 Leu Pro Gly Thr Cys Ser Ser Glu Leu Glu Phe Gly Gly Thr Leu
                 680                 685                 690

 Glu Asp Glu Glu Pro Ala Gln Glu Glu Pro Glu Pro Ile Thr Ala
                 695                 700                 705

 Ser Gly Ser Leu Lys Ala Leu Arg Lys Leu Leu Thr Ala Ser Val
                 710                 715                 720

 Glu Val Pro Val Asp Ser Ala Pro Val Met Glu Glu Asp Thr Asn
                 725                 730                 735

 Gly Glu Ser His Val Pro Gln Glu Asn Glu Glu Glu Glu Glu Lys
                 740                 745                 750

 Glu Pro Ser Gln Ala Ala Ala Ile His Pro Asp Asn Cys Glu Glu
                 755                 760                 765

 Ser Glu Val Ser Glu Arg Glu Ala Gln Pro Pro Cys Pro Glu Ala
                 770                 775                 780

 His Gly Glu Glu Leu Gly Gly Phe Pro Glu Val Gly Ser Pro Ala
                 785                 790                 795

 Ser Pro Pro Ala Ser Gly Gly Leu Thr Glu Glu Pro Leu Gly Pro
                 800                 805                 810

 Met Glu Gly Glu Leu Pro Gly Glu Ala Cys Thr Leu Thr Ala His
                 815                 820                 825

 Glu Gly Arg Gly Gly Lys Cys Thr Glu Glu Gly Asp Ala Ser Gln
                 830                 835                 840

 Gln Glu Gly Cys Thr Leu Gly Ser Asp Pro Ile Cys Leu Ser Glu
                 845                 850                 855

 Ser Gln Val Ser Glu Glu Gln Glu Glu Met Gly Gly Gln Ser Ser
                 860                 865                 870

 Ala Ala Gln Ala Thr Ala Ser Val Asn Ala Glu Glu Ile Lys Val
                 875                 880                 885

 Ala Arg Ile His Glu Cys Gln Trp Val Val Glu Asp Ala Pro Asn
                 890                 895                 900

 Pro Asp Val Leu Leu Ser His Lys Asp Asp Val Lys Glu Gly Glu
                 905                 910                 915

 Gly Gly Gln Glu Ser Phe Pro Glu Leu Pro Ser Glu Glu
                 920                 925

<210> 3118
<211> 6919
<212> DNA
<213> Homo sapien

<400> 3118
 cccacggatc atcagaaggc gcggacctgg aggaggcgcc ccagaaggcg 50

 acgcctcttg cctcctgtct ctcgcctctc gaaggaagtt tgctcttaat 100

 ttcagagccg ggttcgccgt cggatcaacc tccaggagct agcagcgggc 150

 gcggaccggg cagtttccgc gctcagcaca ggcagctcgc ggtcatgggc 200

 ggctcagcct ccagccagct ggacgagggc aagtgcgctt acatccgagg 250

 gaaaactgag gctgccatca aaaacttcag tccctactac agtcgtcagt 300

 actctgtggc tttctgcaat cacgtgcgca ctgaagtaga acagcaaaga 350

 gatttaacgt cacagttttt gaagaccaag ccaccattgg cgcctggaac 400

 tattttgtat gaagcagagc tatcacaatt ttctgaagac ataaagaagt 450

 ggaaggagag atacgttgta gttaaaaatg attatgctgt ggagagctat 500

 gagaataaag aggcctatca gagaggagct gctcctaaat gtcgaattct 550

 tccagccggt ggcaaggtgt taacctcaga agatgaatat aatctgttgt 600

 ctgacaggca tttcccagac cctcttgcct ccagtgagaa ggagaacact 650

 cagccctttg tggtcctgcc caaggaattc ccagtgtacc tgtggcagcc 700

 cttcttcaga cacggctact tctgcttcca cgaggctgct gaccagaaga 750

 ggtttagtgc cctcctgagt gactgcgtca ggcatctcaa tcatgattac 800

 atgaagcaga tgacatttga agcccaagcc tttttagaag ctgtgcaatt 850

 cttccgacag gagaagggtc actatggttc ctgggaaatg atcactgggg 900

 atgaaatcca gatcctgagt aacctggtga tggaggagct cctgcccact 950

 cttcagacag acctgctgcc taagatgaag gggaagaaga atgacagaaa 1000

 gaggacgtgg cttggtctcc tcgaggaggc ctacaccctg gttcagcatc 1050

 aagtttcaga aggattaagt gccttgaagg aggaatgcag agctctgaca 1100

 aagggcctgg aaggaacgat ccgttctgac atggatcaga ttgtgaactc 1150

 aaagaactat ttaattggaa agatcaaagc gatggtggcc cagccggcgg 1200

 agaaaagctg cttggagagt gtgcagccat tcctggcatc catcctggag 1250

 gagctcatgg gaccagtgag ctcgggattc agtgaagtac gtgtactctt 1300

 tgagaaagag gtgaatgaag tcagccagaa cttccagacc accaaagaca 1350

 gtgtccagct aaaggagcat ctagaccggc ttatgaatct tccgctgcat 1400

 tccgtgaaga tggaaccttg ttatactaaa gtcaacctgc ttcacgagcg 1450

 cctgcaggat ctcaagagcc gcttcagatt cccccacatt gatctggtgg 1500

 ttcagaggac acagaactac atgcaggagc taatggagaa tgcagtgttc 1550

 acttttgagc agttgctttc cccacatctc caaggagagg cctccaaaac 1600

 tgcagttgcc attgagaagg ttaaactccg agtcttaaag caatatgatt 1650

 atgacagcag caccatccga aagaagatat ttcaagaggc actagttcaa 1700

 atcacacttc ccactgtgca gaaggcactg gcgtccacat gcaaaccaga 1750

 gcttcagaaa tacgagcagt tcatctttgc agatcatacc aatatgattc 1800

 acgttgaaaa tgtctatgag gagattttac atcagatcct gcttgatgaa 1850

 actctgaaag tgataaagga agctgctatc ttgaagaaac acaacttatt 1900

 tgaagataac atggccttgc ccagtgaaag tgtgtccagc ttaacagatc 1950

 taaagccccc cacagggtca aaccaggcca gccctgccag gagagcttct 2000

 gccattctgc caggagttct gggtagtgag accctcagta acgaagtatt 2050

 ccaggagtca gaggaagaga agcagcctga ggtccctagc tcgttggcca 2100

 aaggagaaag cctttctctc cctgggccaa gcccaccccc agatgggact 2150

 gagcaggtga ttatttcaag agtggatgac cccgtggtga atcctgtggc 2200

 aacagaggac acagcaggac tcccgggcac atgctcatca gagctggagt 2250

 ttggagggac ccttgaggat gaagaacccg cccaggaaga gccagaaccc 2300

 atcactgcct cgggttcttt gaaggcgctc agaaagttgc tgacagcgtc 2350

 cgtggaagta ccagtggact ctgctccagt gatggaagaa gatacgaatg 2400

 gggagagcca cgttccccaa gaaaatgaag aagaagagga aaaagagccc 2450

 agtcaggcag ctgccatcca ccccgacaac tgtgaagaaa gtgaagtcag 2500

 cgagagggag gcccaacctc cctgtcccga ggcccatggg gaggagttgg 2550

 ggggatttcc agaggtaggc agcccagcct ctccgccagc cagtggaggg 2600

 ctcaccgagg agcccctggg gcccatggag ggggagctcc caggagaggc 2650

 ctgcacactc actgcccatg aaggaagagg gggcaagtgt accgaggaag 2700

 gggatgcctc acagcaagag ggctgcacct taggttctga ccccatctgc 2750

 ctcagtgaga gccaggtttc tgaggaacaa gaagagatgg gagggcaaag 2800

 cagcgcggcc caggccacgg ccagtgtgaa tgcagaggag atcaaggtag 2850

 cccgtattca tgagtgtcag tgggtggtgg aggatgctcc aaacccggat 2900

 gtcctgctgt cacacaaaga tgacgtgaag gagggagaag gtggtcagga 2950

 gagtttccca gagctgccct cagaggagtg aaagggacaa tttggctgaa 3000

 gtctttctct gaaaaaagcc aaagcgttat aggggtacac ttaggggttg 3050

 catgcaagct gttaccaaaa aatttttaag tattttctta atttgaataa 3100

 taaaaccaga ggaaatgcat acagggcatg agcaactgag gcaaaccttt 3150

 gtggacatga attgttctac gatgaatttt tgctttagta ttttaataag 3200

 aattacaaag acaatggcat acttggggtg agagggagct gaggatgtct 3250

 gaggagggaa tagtattgca gggaagactg agaaaacagt aggatgacag 3300

 ttttgagtat actctgcact tttcaattgt gcaatcttct tgtgcacttt 3350

 aaggcttttt aattttgttt gagaatgcaa atgtatactg taagtctacc 3400

 tttactatct actatgccta cttcaccatc tcttaaggac tcggcatttg 3450

 tccacagtca gactgcaaga gagggtaggt catgaacagt cacccgtgct 3500

 ggctgtagcc cccacagagg caatcatgcc caatagattc aagagaagct 3550

 aagcggaaat ggagggtgga aggtgtgatc tgtgggactg tctgggcctg 3600

 ttactcatcc tgctatcaat ttcttattaa ttaatcttga tgattcttat 3650

 taattaatca catttgcagg aaattcagat gaggcaagaa aattttattg 3700

 gcctgggtaa gactgaaagc attccaaatt aggcttagac tgtgcaaagg 3750

 gcttagctaa gttatcgagc ttaaaacccg tcaattaaac aaacattatt 3800

 tgaacagtta ctgcatgcca cgcactgtgt tgggcttagt aataaaaaaa 3850

 agaaaagata agtgcttgtt ctagcataaa ttaaaaggtc caagggaatt 3900

 taatctggaa gagaacatat gccaattttt aaactatgac agcttttttt 3950

 tctctttcca ttcaaatagt cctggttcat tcccagaagg gcacaaaatg 4000

 aatgaataaa taaataaatg aataaagaca aaagccaagg tgtatgctct 4050

 caagttccaa agatgttatc aaamgctgaa atcatttgtt tggtcattca 4100

 gcaagctaat tgagtctctg ttatatacca agcactgggg ataccatggc 4150

 gaaaaacaac tttgttcctt cctcctagaa cttacatttt aatggaaata 4200

 gacaaaacac atcttcttaa cggatggtga cctataacca ttaatgttga 4250

 aaatggaaga gacttgcttc caaaagatta aaaggagttg ttcttttctc 4300

 cttcagaaaa ataccagatc atttcctaaa atctccagtc ccaagtatta 4350

 catcgtggtt tccctccccg actttttatt ttattttatt ctattttttt 4400

 gagatggagt ctcgctctgt cgccaaggct ggagtgcagt ggtgtgatct 4450

 cggctcactg caacctccgc ctcctgggtt caggagattc tcctctgtca 4500

 gcgtcccaag tagctggaat tacagccatg cggcaccatt cccggctaat 4550

 ttttgtattt ttggtggaga tgggttttca ccatgttggc caggctggtc 4600

 tcraactcct gatttcaggc gatccaccca cctcgacttc ccaaagtgct 4650

 gggattacag cgtgagctac ctggcccctc cccaaatttt aacatcagat 4700

 ctcaacatat ttgttgagaa cttgtttaga tcatcactat cgagtaaatt 4750

 tatgtcagtt ctttagagca tttgcttcac acacagttca accatttaac 4800

 cagaaattaa aatatcaccc ttttcagccc tcccatgaag aatttctagg 4850

 tcataaacat gaataatact cagtatatgt ataatatcat atttaattgt 4900

 tgcaactttt cttggcgtgt ttaaatcctc atgtctttga gggatcccac 4950

 cacaggtgaa ggaagtaaag accacttctc ccccagtctc tgctttctgc 5000

 agtgctcact catatcctgg catttagcat ggtgtgttga aattaggttt 5050

 acttcttgtc tctccaagtg gctcctctct taaaagacag aaactagggt 5100

 ttagtcatca tttgtgcttc ctgctagaaa cccacagcct tgaataatgg 5150

 cttcctgcct ccttgagtca ctttaatatc cctggtgcat aggacctggc 5200

 atgcgtcagg ctgctcggga aatgtgggaa ctggacaccc agaacactgc 5250

 tgtgctgggg ctatttgggg cctgctgtca ggcagaaaga cgttttgaat 5300

 tgggctttct gcccttgttg agttttctct taagtaaagt ccaaagtcca 5350

 aggggcagat ggccagatgc actgcccagt aaggcaggaa gccaaagagg 5400

 cagtgccagc cccacaaagg ctgcccgact ccctgggaca gtagtgtgga 5450

 gtcccagccc aggctgacct cacaccggag cttcctagct tcctttcttt 5500

 gctcaatgca gggcttcttg caccccctgg aaagctaaga gatttttttc 5550

 aaccctaaaa gagagtacct ttcactgcat tggatggatg aacatcagtg 5600

 ccctaacttt atccatcatg taggtcaggg aggactgggc actatttggc 5650

 aggatgtact ccagaatata atcaaagaat tttctgtaca tatttcacta 5700

 aagacaagtt tttgggctgg atgtggtagc ttacacctat aatcccagca 5750

 ctttgggagg ctgaggtgag agggtcactt gagcccagga gttctagaca 5800

 agcctgggaa acatagcaag atctcatcct tacaaaaaat aataatggtg 5850

 tgtgcctgca gtcctagcta cttgggtggt tgaggcagga ggattgtttg 5900

 agcgagggaa gttgaggctg cagtgaacta tgattttacc actgcactcc 5950

 agcttgggcg acggagtgag accctgtctc aaaaaaaaaa aaagttttct 6000

 agaataagca ggatgattgt ttaatttgaa gatggaacag gaaactagag 6050

 tgcatttaaa atactctgtc ttcattttaa catgttgaat ggaataactg 6100

 catatcacca tgagtttgtt ttgcttttca tacagacttg tatgtgtcat 6150

 ttgagtggtt tccagattgg agcgaggtta ttctgatcta aatgaacagc 6200

 atttttttcc ttagcctctg tttgccactc tgggtatcgt ctcctatggc 6250

 aaagccatta gaaatgcata aaacctcgag acatggtttt tggcaaaaac 6300

 tccatgactt taaactagct cttttactac tgacctttca cagagaaaaa 6350

 atatttccct tgaaaaaaac tgggcttgtc attttttccc ttgtagcttt 6400

 aagcagagac ataagtgcct tgcattacac atagtaaact ttctttaaaa 6450

 aaaaaaaaaa aagattttgg agactaccag ggtaagattc caacttgtcc 6500

 aaaagctttc tggccttaca tattttatta taaaaattct caagtctggt 6550

 aatcttctat gtcagagcta gtgatttcaa aaggtttcac aattccccaa 6600

 gacaaaagtg attttcgttc attataataa ggttaagtga tatgtgattc 6650

 ataacaattt tgatgtgaag aagggaagga catcattgac ttaataatag 6700

 tatcagtcgg tgcaacagtt ggcaacatgt gccttcacac tttaccataa 6750

 agagacgggt ttgagggttt gccttctaaa gtctgcaact tcaagaaaaa 6800

 aaatcgacac tgtggattga ctttcccggt cactatataa agcaaataaa 6850

 cttaaaacac tttgtaacca tgtatttact ctgccaggtg cctatattcc 6900

 aataaaatgt tcatccttg 6919

<210> 3119
<211> 928
<212> PRT
<213> Homo sapien

<400> 3119
 Met Gly Gly Ser Ala Ser Ser Gln Leu Asp Glu Gly Lys Cys Ala
   1               5                  10                  15

 Tyr Ile Arg Gly Lys Thr Glu Ala Ala Ile Lys Asn Phe Ser Pro
                  20                  25                  30

 Tyr Tyr Ser Arg Gln Tyr Ser Val Ala Phe Cys Asn His Val Arg
                  35                  40                  45

 Thr Glu Val Glu Gln Gln Arg Asp Leu Thr Ser Gln Phe Leu Lys
                  50                  55                  60

 Thr Lys Pro Pro Leu Ala Pro Gly Thr Ile Leu Tyr Glu Ala Glu
                  65                  70                  75

 Leu Ser Gln Phe Ser Glu Asp Ile Lys Lys Trp Lys Glu Arg Tyr
                  80                  85                  90

 Val Val Val Lys Asn Asp Tyr Ala Val Glu Ser Tyr Glu Asn Lys
                  95                 100                 105

 Glu Ala Tyr Gln Arg Gly Ala Ala Pro Lys Cys Arg Ile Leu Pro
                 110                 115                 120

 Ala Gly Gly Lys Val Leu Thr Ser Glu Asp Glu Tyr Asn Leu Leu
                 125                 130                 135

 Ser Asp Arg His Phe Pro Asp Pro Leu Ala Ser Ser Glu Lys Glu
                 140                 145                 150

 Asn Thr Gln Pro Phe Val Val Leu Pro Lys Glu Phe Pro Val Tyr
                 155                 160                 165

 Leu Trp Gln Pro Phe Phe Arg His Gly Tyr Phe Cys Phe His Glu
                 170                 175                 180

 Ala Ala Asp Gln Lys Arg Phe Ser Ala Leu Leu Ser Asp Cys Val
                 185                 190                 195

 Arg His Leu Asn His Asp Tyr Met Lys Gln Met Thr Phe Glu Ala
                 200                 205                 210

 Gln Ala Phe Leu Glu Ala Val Gln Phe Phe Arg Gln Glu Lys Gly
                 215                 220                 225

 His Tyr Gly Ser Trp Glu Met Ile Thr Gly Asp Glu Ile Gln Ile
                 230                 235                 240

 Leu Ser Asn Leu Val Met Glu Glu Leu Leu Pro Thr Leu Gln Thr
                 245                 250                 255

 Asp Leu Leu Pro Lys Met Lys Gly Lys Lys Asn Asp Arg Lys Arg
                 260                 265                 270

 Thr Trp Leu Gly Leu Leu Glu Glu Ala Tyr Thr Leu Val Gln His
                 275                 280                 285

 Gln Val Ser Glu Gly Leu Ser Ala Leu Lys Glu Glu Cys Arg Ala
                 290                 295                 300

 Leu Thr Lys Gly Leu Glu Gly Thr Ile Arg Ser Asp Met Asp Gln
                 305                 310                 315

 Ile Val Asn Ser Lys Asn Tyr Leu Ile Gly Lys Ile Lys Ala Met
                 320                 325                 330

 Val Ala Gln Pro Ala Glu Lys Ser Cys Leu Glu Ser Val Gln Pro
                 335                 340                 345

 Phe Leu Ala Ser Ile Leu Glu Glu Leu Met Gly Pro Val Ser Ser
                 350                 355                 360

 Gly Phe Ser Glu Val Arg Val Leu Phe Glu Lys Glu Val Asn Glu
                 365                 370                 375

 Val Ser Gln Asn Phe Gln Thr Thr Lys Asp Ser Val Gln Leu Lys
                 380                 385                 390

 Glu His Leu Asp Arg Leu Met Asn Leu Pro Leu His Ser Val Lys
                 395                 400                 405

 Met Glu Pro Cys Tyr Thr Lys Val Asn Leu Leu His Glu Arg Leu
                 410                 415                 420

 Gln Asp Leu Lys Ser Arg Phe Arg Phe Pro His Ile Asp Leu Val
                 425                 430                 435

 Val Gln Arg Thr Gln Asn Tyr Met Gln Glu Leu Met Glu Asn Ala
                 440                 445                 450

 Val Phe Thr Phe Glu Gln Leu Leu Ser Pro His Leu Gln Gly Glu
                 455                 460                 465

 Ala Ser Lys Thr Ala Val Ala Ile Glu Lys Val Lys Leu Arg Val
                 470                 475                 480

 Leu Lys Gln Tyr Asp Tyr Asp Ser Ser Thr Ile Arg Lys Lys Ile
                 485                 490                 495

 Phe Gln Glu Ala Leu Val Gln Ile Thr Leu Pro Thr Val Gln Lys
                 500                 505                 510

 Ala Leu Ala Ser Thr Cys Lys Pro Glu Leu Gln Lys Tyr Glu Gln
                 515                 520                 525

 Phe Ile Phe Ala Asp His Thr Asn Met Ile His Val Glu Asn Val
                 530                 535                 540

 Tyr Glu Glu Ile Leu His Gln Ile Leu Leu Asp Glu Thr Leu Lys
                 545                 550                 555

 Val Ile Lys Glu Ala Ala Ile Leu Lys Lys His Asn Leu Phe Glu
                 560                 565                 570

 Asp Asn Met Ala Leu Pro Ser Glu Ser Val Ser Ser Leu Thr Asp
                 575                 580                 585

 Leu Lys Pro Pro Thr Gly Ser Asn Gln Ala Ser Pro Ala Arg Arg
                 590                 595                 600

 Ala Ser Ala Ile Leu Pro Gly Val Leu Gly Ser Glu Thr Leu Ser
                 605                 610                 615

 Asn Glu Val Phe Gln Glu Ser Glu Glu Glu Lys Gln Pro Glu Val
                 620                 625                 630

 Pro Ser Ser Leu Ala Lys Gly Glu Ser Leu Ser Leu Pro Gly Pro
                 635                 640                 645

 Ser Pro Pro Pro Asp Gly Thr Glu Gln Val Ile Ile Ser Arg Val
                 650                 655                 660

 Asp Asp Pro Val Val Asn Pro Val Ala Thr Glu Asp Thr Ala Gly
                 665                 670                 675

 Leu Pro Gly Thr Cys Ser Ser Glu Leu Glu Phe Gly Gly Thr Leu
                 680                 685                 690

 Glu Asp Glu Glu Pro Ala Gln Glu Glu Pro Glu Pro Ile Thr Ala
                 695                 700                 705

 Ser Gly Ser Leu Lys Ala Leu Arg Lys Leu Leu Thr Ala Ser Val
                 710                 715                 720

 Glu Val Pro Val Asp Ser Ala Pro Val Met Glu Glu Asp Thr Asn
                 725                 730                 735

 Gly Glu Ser His Val Pro Gln Glu Asn Glu Glu Glu Glu Glu Lys
                 740                 745                 750

 Glu Pro Ser Gln Ala Ala Ala Ile His Pro Asp Asn Cys Glu Glu
                 755                 760                 765

 Ser Glu Val Ser Glu Arg Glu Ala Gln Pro Pro Cys Pro Glu Ala
                 770                 775                 780

 His Gly Glu Glu Leu Gly Gly Phe Pro Glu Val Gly Ser Pro Ala
                 785                 790                 795

 Ser Pro Pro Ala Ser Gly Gly Leu Thr Glu Glu Pro Leu Gly Pro
                 800                 805                 810

 Met Glu Gly Glu Leu Pro Gly Glu Ala Cys Thr Leu Thr Ala His
                 815                 820                 825

 Glu Gly Arg Gly Gly Lys Cys Thr Glu Glu Gly Asp Ala Ser Gln
                 830                 835                 840

 Gln Glu Gly Cys Thr Leu Gly Ser Asp Pro Ile Cys Leu Ser Glu
                 845                 850                 855

 Ser Gln Val Ser Glu Glu Gln Glu Glu Met Gly Gly Gln Ser Ser
                 860                 865                 870

 Ala Ala Gln Ala Thr Ala Ser Val Asn Ala Glu Glu Ile Lys Val
                 875                 880                 885

 Ala Arg Ile His Glu Cys Gln Trp Val Val Glu Asp Ala Pro Asn
                 890                 895                 900

 Pro Asp Val Leu Leu Ser His Lys Asp Asp Val Lys Glu Gly Glu
                 905                 910                 915

 Gly Gly Gln Glu Ser Phe Pro Glu Leu Pro Ser Glu Glu
                 920                 925

<210> 3120
<211> 1875
<212> DNA
<213> Homo sapien

<400> 3120
 agctgcggcg gccgcaggtt ccaaagcggg tccgagccgc cgccgcgcgc 50

 gcgccgcgca ctgcagcccc aggccccggc cccccaccca cgtctgcgtt 100

 gctgccccgc ctgggccagg ccccaaaggc aaggacaaag cagctgtcag 150

 ggaacctccg ccggagtcga atttacgtgc agctgccggc aaccacaggt 200

 tccaagatgg tttgcggggg cttcgcgtgt tccaagaact gcctgtgcgc 250

 cctcaacctg ctttacacct tggttagtct gctgctaatt ggaattgctg 300

 cgtggggcat tggcttcggg ctgatttcca gtctccgagt ggtcggcgtg 350

 gtcattgcag tgggcatctt cttgttcctg attgctttag tgggtctgat 400

 tggagctgta aaacatcatc aggtgttgct atttttttat atgattattc 450

 tgttacttgt atttattgtt cagttttctg tatcttgcgc ttgtttagcc 500

 ctgaaccagg agcaacaggg tcagcttctg gaggttggtt ggaacaatac 550

 ggcaagtgct cgaaatgaca tccagagaaa tctaaactgc tgtgggttcc 600

 gaagtgttaa cccaaatgac acctgtctgg ctagctgtgt taaaagtgac 650

 cactcgtgct cgccatgtgc tccaatcata ggagaatatg ctggagaggt 700

 tttgagattt gttggtggca ttggcctgtt cttcagtttt acagagatcc 750

 tgggtgtttg gctgacctac agatacagga accagaaaga cccccgcgcg 800

 aatcctagtg cattcctttg atgagaaaac aaggaagatt tcctttcgta 850

 ttatgatctt gttcactttc tgtaattttc tgttaagctc catttgccag 900

 tttaaggaag gaaacactat ctggaaaagt accttattga tagtggaatt 950

 atatattttt actctatgtt tctctacatg tttttttctt tccgttgctg 1000

 aaaaatattt gaaacttgtg gtctctgaag ctcggtggca cctggaattt 1050

 actgtattca ttgtcgggca ctgtccactg tggcctttct tagcattttt 1100

 acctgcagaa aaactttgta tggtaccact gtgttggtta tatggtgaat 1150

 ctgaacgtac atctcactgg tataattata tgtagcactg tgctgtgtag 1200

 atagttccta ctggaaaaag agtggaaatt tattaaaatc agaaagtatg 1250

 agatcctgtt atgttaaggg aaatccaaat tcccaatttt ttttggtctt 1300

 tttaggaaag atgtgttgtg gtaaaaagtg ttagtataaa aatgataatt 1350

 tacttgtagt cttttatgat tacaccaatg tattctagaa atagttatgt 1400

 cttaggaaat tgtggtttaa tttttgactt ttacaggtaa gtgcaaagga 1450

 gaagtggttt catgaaatgt tctaatgtat aataacattt accttcagcc 1500

 tccatcagaa tggaacgagt tttgagtaat caggaagtat atctatatga 1550

 tcttgatatt gttttataat aatttgaagt ctaaaagact gcatttttaa 1600

 acaagttagt attaatgcgt tggcccacgt agcaaaaaga tatttgatta 1650

 tcttaaaaat tgttaaatac cgttttcatg aaagttctca gtattgtaac 1700

 agcaacttgt caaacctaag catatttgaa tatgatctcc cataatttga 1750

 aattgaaatc gtattgtgtg gctctgtata ttctgttaaa aaattaaagg 1800

 acagaaacct ttctttgtgt atgcatgttt gaattaaaag aaagtaatgg 1850

 aagaattgat cgatgaaaaa aaaaa 1875

<210> 3121
<211> 204
<212> PRT
<213> Homo sapien

<400> 3121
 Met Val Cys Gly Gly Phe Ala Cys Ser Lys Asn Cys Leu Cys Ala
   1               5                  10                  15

 Leu Asn Leu Leu Tyr Thr Leu Val Ser Leu Leu Leu Ile Gly Ile
                  20                  25                  30

 Ala Ala Trp Gly Ile Gly Phe Gly Leu Ile Ser Ser Leu Arg Val
                  35                  40                  45

 Val Gly Val Val Ile Ala Val Gly Ile Phe Leu Phe Leu Ile Ala
                  50                  55                  60

 Leu Val Gly Leu Ile Gly Ala Val Lys His His Gln Val Leu Leu
                  65                  70                  75

 Phe Phe Tyr Met Ile Ile Leu Leu Leu Val Phe Ile Val Gln Phe
                  80                  85                  90

 Ser Val Ser Cys Ala Cys Leu Ala Leu Asn Gln Glu Gln Gln Gly
                  95                 100                 105

 Gln Leu Leu Glu Val Gly Trp Asn Asn Thr Ala Ser Ala Arg Asn
                 110                 115                 120

 Asp Ile Gln Arg Asn Leu Asn Cys Cys Gly Phe Arg Ser Val Asn
                 125                 130                 135

 Pro Asn Asp Thr Cys Leu Ala Ser Cys Val Lys Ser Asp His Ser
                 140                 145                 150

 Cys Ser Pro Cys Ala Pro Ile Ile Gly Glu Tyr Ala Gly Glu Val
                 155                 160                 165

 Leu Arg Phe Val Gly Gly Ile Gly Leu Phe Phe Ser Phe Thr Glu
                 170                 175                 180

 Ile Leu Gly Val Trp Leu Thr Tyr Arg Tyr Arg Asn Gln Lys Asp
                 185                 190                 195

 Pro Arg Ala Asn Pro Ser Ala Phe Leu
                 200

<210> 3122
<211> 1192
<212> DNA
<213> Homo sapien

<400> 3122
 cggcgactga ccgtggtcgt gggcggacgg cggcttgcag cgtggaggag 50

 ctggggtcgc tgtgggtcgc gaagcagagc ccgggacgtg cgcgcttggt 100

 gcacgatcct gaaggggagc tccgaggggc ccgggtcgcc agggctgctg 150

 cggccattcc cggagcccgg cgcggggccc gcgagatact ggtttaggcc 200

 gtcccagggc tccgggcgca cccggtggcc gctgctgcag cggagggagc 250

 gcggcggcgc gggggctcgg agacagcgtt tctcccggaa gtcttcctcg 300

 ggcagcaggt gggaagtggg agccggagcg gcagctggca gcgttctctc 350

 cgcaggtcgg caccatgcgc cctgcagccc tgcgcggggc cctgctgggc 400

 tgcctctgcc tggcgttgct ttgcctgggc ggtgcggaca agcgcctgcg 450

 tgacaaccat gagtggaaaa aactaattat ggttcagcac tggcctgaga 500

 cagtatgcga gaaaattcaa aacgactgta gagaccctcc ggattactgg 550

 acaatacatg gactatggcc cgataaaagt gaaggatgta atagatcgtg 600

 gcccttcaat ttagaagaga ttaaggatct tttgccagaa atgagggcat 650

 actggcctga cgtaattcac tcgtttccca atcgcagccg cttctggaag 700

 catgagtggg aaaagcatgg gacctgcgcc gcccaggtgg atgcgctcaa 750

 ctcccagaag aagtactttg gcagaagcct ggaactctac agggagctgg 800

 acctcaacag tgtgcttcta aaattgggga taaaaccatc catcaattac 850

 taccaagttg cagattttaa agatgccctt gccagagtat atggagtgat 900

 acccaaaatc cagtgccttc caccaagcca ggatgaggaa gtacagacaa 950

 ttggtcagat agaactgtgc ctcactaagc aagaccagca gctgcaaaac 1000

 tgcaccgagc cgggggagca gccgtccccc aagcaggaag tctggctggc 1050

 aaatggggcc gccgagagcc ggggtctgag agtctgtgaa gatggcccag 1100

 tcttctatcc cccacctaaa aagaccaagc attgatgccc aagttttgga 1150

 aatattctgt tttaaaaagc aagagaaatt cacaaactgc ag 1192

<210> 3123
<211> 256
<212> PRT
<213> Homo sapien

<400> 3123
 Met Arg Pro Ala Ala Leu Arg Gly Ala Leu Leu Gly Cys Leu Cys
   1               5                  10                  15

 Leu Ala Leu Leu Cys Leu Gly Gly Ala Asp Lys Arg Leu Arg Asp
                  20                  25                  30

 Asn His Glu Trp Lys Lys Leu Ile Met Val Gln His Trp Pro Glu
                  35                  40                  45

 Thr Val Cys Glu Lys Ile Gln Asn Asp Cys Arg Asp Pro Pro Asp
                  50                  55                  60

 Tyr Trp Thr Ile His Gly Leu Trp Pro Asp Lys Ser Glu Gly Cys
                  65                  70                  75

 Asn Arg Ser Trp Pro Phe Asn Leu Glu Glu Ile Lys Asp Leu Leu
                  80                  85                  90

 Pro Glu Met Arg Ala Tyr Trp Pro Asp Val Ile His Ser Phe Pro
                  95                 100                 105

 Asn Arg Ser Arg Phe Trp Lys His Glu Trp Glu Lys His Gly Thr
                 110                 115                 120

 Cys Ala Ala Gln Val Asp Ala Leu Asn Ser Gln Lys Lys Tyr Phe
                 125                 130                 135

 Gly Arg Ser Leu Glu Leu Tyr Arg Glu Leu Asp Leu Asn Ser Val
                 140                 145                 150

 Leu Leu Lys Leu Gly Ile Lys Pro Ser Ile Asn Tyr Tyr Gln Val
                 155                 160                 165

 Ala Asp Phe Lys Asp Ala Leu Ala Arg Val Tyr Gly Val Ile Pro
                 170                 175                 180

 Lys Ile Gln Cys Leu Pro Pro Ser Gln Asp Glu Glu Val Gln Thr
                 185                 190                 195

 Ile Gly Gln Ile Glu Leu Cys Leu Thr Lys Gln Asp Gln Gln Leu
                 200                 205                 210

 Gln Asn Cys Thr Glu Pro Gly Glu Gln Pro Ser Pro Lys Gln Glu
                 215                 220                 225

 Val Trp Leu Ala Asn Gly Ala Ala Glu Ser Arg Gly Leu Arg Val
                 230                 235                 240

 Cys Glu Asp Gly Pro Val Phe Tyr Pro Pro Pro Lys Lys Thr Lys
                 245                 250                 255

 His


<210> 3124
<211> 1192
<212> DNA
<213> Homo sapien

<400> 3124
 cggcgactga ccgtggtcgt gggcggacgg cggcttgcag cgtggaggag 50

 ctggggtcgc tgtgggtcgc gaagcagagc ccgggacgtg cgcgcttggt 100

 gcacgatcct gaaggggagc tccgaggggc ccgggtcgcc agggctgctg 150

 cggccattcc cggagcccgg cgcggggccc gcgagatact ggtttaggcc 200

 gtcccagggc tccgggcgca cccggtggcc gctgctgcag cggagggagc 250

 gcggcggcgc gggggctcgg agacagcgtt tctcccggaa gtcttcctcg 300

 ggcagcaggt gggaagtggg agccggagcg gcagctggca gcgttctctc 350

 cgcaggtcgg caccatgcgc cctgcagccc tgcgcggggc cctgctgggc 400

 tgcctctgcc tggcgttgct ttgcctgggc ggtgcggaca agcgcctgcg 450

 tgacaaccat gagtggaaaa aactaattat ggttcagcac tggcctgaga 500

 cagtatgcga gaaaattcaa aacgactgta gagaccctcc ggattactgg 550

 acaatacatg gactatggcc cgataaaagt gaaggatgta atagatcgtg 600

 gcccttcaat ttagaagaga ttaaggatct tttgccagaa atgagggcat 650

 actggcctga cgtaattcac tcgtttccca atcgcagccg cttctggaag 700

 catgagtggg aaaagcatgg gacctgcgcc gcccaggtgg atgcgctcaa 750

 ctcccagaag aagtactttg gcagaagcct ggaactctac agggagctgg 800

 acctcaacag tgtgcttcta aaattgggga taaaaccatc catcaattac 850

 taccaagttg cagattttaa agatgccctt gccagagtat atggagtgat 900

 acccaaaatc cagtgccttc caccaagcca ggatgaggaa gtacagacaa 950

 ttggtcagat agaactgtgc ctcactaagc aagaccagca gctgcaaaac 1000

 tgcaccgagc cgggggagca gccgtccccc aagcaggaag tctggctggc 1050

 aaatggggcc gccgagagcc ggggtctgag agtctgtgaa gatggcccag 1100

 tcttctatcc cccacctaaa aagaccaagc attgatgccc aagttttgga 1150

 aatattctgt tttaaaaagc aagagaaatt cacaaactgc ag 1192

<210> 3125
<211> 256
<212> PRT
<213> Homo sapien

<400> 3125
 Met Arg Pro Ala Ala Leu Arg Gly Ala Leu Leu Gly Cys Leu Cys
   1               5                  10                  15

 Leu Ala Leu Leu Cys Leu Gly Gly Ala Asp Lys Arg Leu Arg Asp
                  20                  25                  30

 Asn His Glu Trp Lys Lys Leu Ile Met Val Gln His Trp Pro Glu
                  35                  40                  45

 Thr Val Cys Glu Lys Ile Gln Asn Asp Cys Arg Asp Pro Pro Asp
                  50                  55                  60

 Tyr Trp Thr Ile His Gly Leu Trp Pro Asp Lys Ser Glu Gly Cys
                  65                  70                  75

 Asn Arg Ser Trp Pro Phe Asn Leu Glu Glu Ile Lys Asp Leu Leu
                  80                  85                  90

 Pro Glu Met Arg Ala Tyr Trp Pro Asp Val Ile His Ser Phe Pro
                  95                 100                 105

 Asn Arg Ser Arg Phe Trp Lys His Glu Trp Glu Lys His Gly Thr
                 110                 115                 120

 Cys Ala Ala Gln Val Asp Ala Leu Asn Ser Gln Lys Lys Tyr Phe
                 125                 130                 135

 Gly Arg Ser Leu Glu Leu Tyr Arg Glu Leu Asp Leu Asn Ser Val
                 140                 145                 150

 Leu Leu Lys Leu Gly Ile Lys Pro Ser Ile Asn Tyr Tyr Gln Val
                 155                 160                 165

 Ala Asp Phe Lys Asp Ala Leu Ala Arg Val Tyr Gly Val Ile Pro
                 170                 175                 180

 Lys Ile Gln Cys Leu Pro Pro Ser Gln Asp Glu Glu Val Gln Thr
                 185                 190                 195

 Ile Gly Gln Ile Glu Leu Cys Leu Thr Lys Gln Asp Gln Gln Leu
                 200                 205                 210

 Gln Asn Cys Thr Glu Pro Gly Glu Gln Pro Ser Pro Lys Gln Glu
                 215                 220                 225

 Val Trp Leu Ala Asn Gly Ala Ala Glu Ser Arg Gly Leu Arg Val
                 230                 235                 240

 Cys Glu Asp Gly Pro Val Phe Tyr Pro Pro Pro Lys Lys Thr Lys
                 245                 250                 255

 His


<210> 3126
<211> 1760
<212> DNA
<213> Homo sapien

<400> 3126
 gaattccgag ctttttattc ctaagaggag aaaatcagta acgggagaag 50

 caggaggatg tccagaagaa atttcatccc ttgctctcgc ccctactctt 100

 tctggtgtta gatcgagcta ccctctaaaa gcagtttaga gtggtaaaaa 150

 aaaaaaaaac acaccaaacg ctcgcagcca caaaagggat gaaatttctt 200

 ctggacatcc tcctgcttct cccgttactg atcgtctgct ccctagagtc 250

 cttcgtgaag ctttttattc ctaagaggag aaaatcagtc accggcgaaa 300

 tcgtgctgat tacaggagct gggcatggaa ttgggagact gactgcctat 350

 gaatttgcta aacttaaaag caagctggtt ctctgggata taaataagca 400

 tggactggag gaaacagctg ccaaatgcaa gggactgggt gccaaggttc 450

 atacctttgt ggtagactgc agcaaccgag aagatattta cagctctgca 500

 aagaaggtga aggcagaaat tggagatgtt agtattttag taaataatgc 550

 tggtgtagtc tatacatcag atttgtttgc tacacaagat cctcagattg 600

 aaaagacttt tgaagttaat gtacttgcac atttctggac tacaaaggca 650

 tttcttcctg caatgacgaa gaataaccat ggccatattg tcactgtggc 700

 ttcggcagct ggacatgtct cggtcccctt cttactggct tactgttcaa 750

 gcaagtttgc tgctgttgga tttcataaaa ctttgacaga tgaactggct 800

 gccttacaaa taactggagt caaaacaaca tgtctgtgtc ctaatttcgt 850

 aaacactggc ttcatcaaaa atccaagtac aagtttggga cccactctgg 900

 aacccgagga agtggtaaac aggctgatgc atgggattct gactgagcag 950

 aagatgattt ttattccatc ttctatagct tttttaacaa cattggaaag 1000

 gatccttcct gagcgtttcc tggcagtttt aaaacgaaaa atcagtgtta 1050

 agtttgatgc agttattgga tataaaatga aagcgcaata agcacctagt 1100

 tttctgaaaa ctgatttacc aggtttaggt tgatgtcatc taatagtgcc 1150

 agaattttaa tgtttgaact tctgtttttt ctaattatcc ccatttcttc 1200

 aatatcattt ttgaggcttt ggcagtcttc atttactacc acttgttctt 1250

 tagccaaaag ctgattacat atgatataaa cagagaaata cctttagagg 1300

 tgactttaag gaaaatgaag aaaaagaacc aaaatgactt tattaaaata 1350

 atttccaaga ttatttgtgg ctcacctgaa ggctttgcaa aatttgtacc 1400

 ataaccgttt atttaacata tatttttatt tttgattgca cttaaatttt 1450

 gtataatttg tgtttctttt tctgttctac ataaaatcag aaacttcaag 1500

 ctctctaaat aaaatgaagg actatatcta gtggtatttc acaatgaata 1550

 tcatgaactc tcaatgggta ggtttcatcc tacccattgc cactctgttt 1600

 cctgagagat acctcacatt ccaatgccaa acatttctgc acagggaagc 1650

 tagaggtgga tacacgtgtt gcaagtataa aagcatcact gggggattta 1700

 aggagaattg agagaatgta cccacaaatg gcagcaataa taaatggatc 1750

 acacttaacg 1760

<210> 3127
<211> 300
<212> PRT
<213> Homo sapien

<400> 3127
 Met Lys Phe Leu Leu Asp Ile Leu Leu Leu Leu Pro Leu Leu Ile
   1               5                  10                  15

 Val Cys Ser Leu Glu Ser Phe Val Lys Leu Phe Ile Pro Lys Arg
                  20                  25                  30

 Arg Lys Ser Val Thr Gly Glu Ile Val Leu Ile Thr Gly Ala Gly
                  35                  40                  45

 His Gly Ile Gly Arg Leu Thr Ala Tyr Glu Phe Ala Lys Leu Lys
                  50                  55                  60

 Ser Lys Leu Val Leu Trp Asp Ile Asn Lys His Gly Leu Glu Glu
                  65                  70                  75

 Thr Ala Ala Lys Cys Lys Gly Leu Gly Ala Lys Val His Thr Phe
                  80                  85                  90

 Val Val Asp Cys Ser Asn Arg Glu Asp Ile Tyr Ser Ser Ala Lys
                  95                 100                 105

 Lys Val Lys Ala Glu Ile Gly Asp Val Ser Ile Leu Val Asn Asn
                 110                 115                 120

 Ala Gly Val Val Tyr Thr Ser Asp Leu Phe Ala Thr Gln Asp Pro
                 125                 130                 135

 Gln Ile Glu Lys Thr Phe Glu Val Asn Val Leu Ala His Phe Trp
                 140                 145                 150

 Thr Thr Lys Ala Phe Leu Pro Ala Met Thr Lys Asn Asn His Gly
                 155                 160                 165

 His Ile Val Thr Val Ala Ser Ala Ala Gly His Val Ser Val Pro
                 170                 175                 180

 Phe Leu Leu Ala Tyr Cys Ser Ser Lys Phe Ala Ala Val Gly Phe
                 185                 190                 195

 His Lys Thr Leu Thr Asp Glu Leu Ala Ala Leu Gln Ile Thr Gly
                 200                 205                 210

 Val Lys Thr Thr Cys Leu Cys Pro Asn Phe Val Asn Thr Gly Phe
                 215                 220                 225

 Ile Lys Asn Pro Ser Thr Ser Leu Gly Pro Thr Leu Glu Pro Glu
                 230                 235                 240

 Glu Val Val Asn Arg Leu Met His Gly Ile Leu Thr Glu Gln Lys
                 245                 250                 255

 Met Ile Phe Ile Pro Ser Ser Ile Ala Phe Leu Thr Thr Leu Glu
                 260                 265                 270

 Arg Ile Leu Pro Glu Arg Phe Leu Ala Val Leu Lys Arg Lys Ile
                 275                 280                 285

 Ser Val Lys Phe Asp Ala Val Ile Gly Tyr Lys Met Lys Ala Gln
                 290                 295                 300

<210> 3128
<211> 1834
<212> DNA
<213> Homo sapien

<400> 3128
 ctcttccctg caaaccatgt ttgccaaagg caaaggctcg gcggtgccct 50

 cggatgggca ggctcgggaa aagttagctt tatacgtcta cgaatattta 100

 ctgcacgtag gagcacagaa atctgcacag actttcttat cggagattcg 150

 atgggaaaaa aacatcacgt tgggagaacc gcctgggttt ttgcactcgt 200

 ggtggtgtgt attttgggac ctttactgtg cagctcctga aaggagagac 250

 acttgtgaac attcaagtga agcaaaagcc tttcatgatt atagtgcagc 300

 agctgccccg agccccgtgc ttggcaacat tccccccaac gatgggatgc 350

 cgggaggccc catcccgcca ggtttctttc agggtcctcc ggggtcacag 400

 ccctcgccgc acgcacagcc tccacctcac aatcctagca gcatgatggg 450

 accccacagt cagcctttta tgtcaccgcg atacgcaggc ggccccaggc 500

 ccccgatcag aatgggaaac cagcctccgg gaggagttcc tgggacacag 550

 ccattgctgc ccaattctat ggatcccaca cgacaacaag gccaccccaa 600

 catgggagga tcaatgcaga gaatgaaccc tccccgaggc atggggccca 650

 tgggtcccgg cccacagaat tacggcagcg gcatgagacc accacccaac 700

 tccctcggcc ccgccatgcc cgggattaac atgggcccgg gagctggcag 750

 accctggccc aatcctaaca gtgctaactc aattccatac tcctcctcat 800

 cacctggtac ctatgtggga ccccctggtg gtggcggtcc tccaggaaca 850

 cccattatgc ccagtcccgc agattcaaca aattccagtg acaacatcta 900

 cacaatgatt aatccagtgc cgcctggagg cagccggtcc aacttcccga 950

 tgggtcccgg ctcggacggt ccgatgggcg gcatgggtgg catggagcca 1000

 caccacatga atggatcatt agggtcaggc gacatagacg gacttccaaa 1050

 aaattctcct aacaacataa gtggcattag caatcctcca ggcacccctc 1100

 gagatgacgg cgagctagga gggaacttcc tccactcctt tcagaacgac 1150

 aattattctc caagcatgac gatgagtgtg tgatcccccc ttctccgaga 1200

 cgctgagaga gcaggcattg caggcgggaa gatgccagaa attatgcaag 1250

 aagtgaggtg tcattatcca ggagctggtg gggagggcat ctccctgctc 1300

 ccctcaaccc cctcccaccc catccacgcc ccctaccttt cccaatttta 1350

 gtttcatgca ataaaaaggc caaacttttt attccataaa acaagaagga 1400

 caaaactctc aaaaatgtat ttcaagtcag tgaccagaaa aatcccaccc 1450

 cttgcccttt ccccaaagga ccttttctgt acatgacact tttttgttgt 1500

 tttttgtttg gggttttacc attgttggga tttttttatt tgttttcagg 1550

 ggggtttttt gggggaaaat ttttttaaat ggaagcttct agcaagcccc 1600

 ccaccccaat caacctctat gctttcttct taaaaaaaaa aaaaaaggaa 1650

 aaaggaaaaa aaaaaaagga aaaccagaag ccctgctgtc tgtctgtgcc 1700

 caagcccttc caccagaaaa gctagtctag gtgtgagagc ccacattgtc 1750

 tgtagccatc aaaaataata ataataaact ggacagttta caatcgttgg 1800

 tttctttcaa aaggcctttt ttggaaagaa gaaa 1834

<210> 3129
<211> 388
<212> PRT
<213> Homo sapien

<400> 3129
 Met Phe Ala Lys Gly Lys Gly Ser Ala Val Pro Ser Asp Gly Gln
   1               5                  10                  15

 Ala Arg Glu Lys Leu Ala Leu Tyr Val Tyr Glu Tyr Leu Leu His
                  20                  25                  30

 Val Gly Ala Gln Lys Ser Ala Gln Thr Phe Leu Ser Glu Ile Arg
                  35                  40                  45

 Trp Glu Lys Asn Ile Thr Leu Gly Glu Pro Pro Gly Phe Leu His
                  50                  55                  60

 Ser Trp Trp Cys Val Phe Trp Asp Leu Tyr Cys Ala Ala Pro Glu
                  65                  70                  75

 Arg Arg Asp Thr Cys Glu His Ser Ser Glu Ala Lys Ala Phe His
                  80                  85                  90

 Asp Tyr Ser Ala Ala Ala Ala Pro Ser Pro Val Leu Gly Asn Ile
                  95                 100                 105

 Pro Pro Asn Asp Gly Met Pro Gly Gly Pro Ile Pro Pro Gly Phe
                 110                 115                 120

 Phe Gln Gly Pro Pro Gly Ser Gln Pro Ser Pro His Ala Gln Pro
                 125                 130                 135

 Pro Pro His Asn Pro Ser Ser Met Met Gly Pro His Ser Gln Pro
                 140                 145                 150

 Phe Met Ser Pro Arg Tyr Ala Gly Gly Pro Arg Pro Pro Ile Arg
                 155                 160                 165

 Met Gly Asn Gln Pro Pro Gly Gly Val Pro Gly Thr Gln Pro Leu
                 170                 175                 180

 Leu Pro Asn Ser Met Asp Pro Thr Arg Gln Gln Gly His Pro Asn
                 185                 190                 195

 Met Gly Gly Ser Met Gln Arg Met Asn Pro Pro Arg Gly Met Gly
                 200                 205                 210

 Pro Met Gly Pro Gly Pro Gln Asn Tyr Gly Ser Gly Met Arg Pro
                 215                 220                 225

 Pro Pro Asn Ser Leu Gly Pro Ala Met Pro Gly Ile Asn Met Gly
                 230                 235                 240

 Pro Gly Ala Gly Arg Pro Trp Pro Asn Pro Asn Ser Ala Asn Ser
                 245                 250                 255

 Ile Pro Tyr Ser Ser Ser Ser Pro Gly Thr Tyr Val Gly Pro Pro
                 260                 265                 270

 Gly Gly Gly Gly Pro Pro Gly Thr Pro Ile Met Pro Ser Pro Ala
                 275                 280                 285

 Asp Ser Thr Asn Ser Ser Asp Asn Ile Tyr Thr Met Ile Asn Pro
                 290                 295                 300

 Val Pro Pro Gly Gly Ser Arg Ser Asn Phe Pro Met Gly Pro Gly
                 305                 310                 315

 Ser Asp Gly Pro Met Gly Gly Met Gly Gly Met Glu Pro His His
                 320                 325                 330

 Met Asn Gly Ser Leu Gly Ser Gly Asp Ile Asp Gly Leu Pro Lys
                 335                 340                 345

 Asn Ser Pro Asn Asn Ile Ser Gly Ile Ser Asn Pro Pro Gly Thr
                 350                 355                 360

 Pro Arg Asp Asp Gly Glu Leu Gly Gly Asn Phe Leu His Ser Phe
                 365                 370                 375

 Gln Asn Asp Asn Tyr Ser Pro Ser Met Thr Met Ser Val
                 380                 385

<210> 3130
<211> 1690
<212> DNA
<213> Homo sapien

<400> 3130
 ggcacgagga aggtttttgc tgcgccaacg cagtgaccga aggctccgct 50

 cacgcccggc ctgatcctgc ctgaagatgg tgccactggt ggctgtggta 100

 tcagggcccc gtgcccagct ctttgcctgc ctgctcaggc tgggcactca 150

 gcaggtcggc ccccttcagc tgcacaccgg ggccagccat gcggccagga 200

 accattatga ggtgctggtg ctgggtgggg gcagtggcgg aatcaccatg 250

 gctgcccgca tgaagaggaa agtgggtgca gagaatgtgg ccattgttga 300

 gcccagtgag agacatttct accagccaat ctggacactg gtgggtgctg 350

 gtgccaaaca attgtcctca tctggtcgtc ccacggcaag tgtgattcca 400

 tctggtgtag aatggatcaa agctagagtg actgagttga acccagacaa 450

 gaactgcatt cacacagatg acgacgagaa gatctcctac cgatatctta 500

 ttattgctct cggaatccag ctggactatg agaagattaa aggcctacct 550

 gaaggtttcg ctcatcccaa aatagggtcg aattattcag ttaagactgt 600

 agagaagaca tggaaagctc tgcaggactt caaagagggc aatgccatct 650

 tcaccttccc aaatactcca gtgaagtgtg ctggagcccc tcagaagatc 700

 atgtacttat cagaagccta cttcaggaag acagggaagc gatccaaggc 750

 caatatcatt ttcaacactt ctcttggagc cattttcggg gttaagaagt 800

 atgcagatgc cctgcaggag atcatccagg agcggaacct cactgttaac 850

 tacaagaaaa acctcattga agtccgagcc gataaacaag aggctgtatt 900

 tgagaacctg gacaaaccag gagagaccca agtgatttca tatgaaatgc 950

 ttcatgtcac acctccaatg agcccaccag atgtcctcaa gaccagtcct 1000

 gtggctgatg ctgctggttg ggtggatgtg gataaagaaa ctctgcaaca 1050

 caggaggtac ccaaatgtgt ttgggattgg ggactgcacc aaccttccta 1100

 cgtcaaagac cgctgctgca gtagctgccc agtcaggaat acttgatagg 1150

 acaatttctg taattatgaa gaatcaaaca ccaacaaaga agtatgatgg 1200

 ctacacatca tgtccactgg tgaccggcta caaccgtgtg attcttgctg 1250

 agtttgacta caaagcagag ccgctagaaa ccttcccctt tgatcaaagc 1300

 aaagagcgcc tttccatgta tctcatgaaa gctgacctga tgcctttcct 1350

 gtattggaat atgatgctaa ggggttactg gggaggacca gcgtttctgc 1400

 gcaagttgtt tcatctaggt atgagttaag gatggctcag cacttgctca 1450

 tcttggatgg cttctgggcc aaaactgcag tcactgaatg accaagagca 1500

 gcacgaagga cttggaacct atccttgtaa agagttcctt gatgggtaat 1550

 ggtgaccaaa tgcctccctt ttcagtacct ttgaacagca accatgtggg 1600

 ctactcatga tgggcttgat tctttgggaa taataaaatg aaataatact 1650

 tttattttct gaataaaagt ttgtcactga aaaaaaaaaa 1690

<210> 3131
<211> 450
<212> PRT
<213> Homo sapien

<400> 3131
 Met Val Pro Leu Val Ala Val Val Ser Gly Pro Arg Ala Gln Leu
   1               5                  10                  15

 Phe Ala Cys Leu Leu Arg Leu Gly Thr Gln Gln Val Gly Pro Leu
                  20                  25                  30

 Gln Leu His Thr Gly Ala Ser His Ala Ala Arg Asn His Tyr Glu
                  35                  40                  45

 Val Leu Val Leu Gly Gly Gly Ser Gly Gly Ile Thr Met Ala Ala
                  50                  55                  60

 Arg Met Lys Arg Lys Val Gly Ala Glu Asn Val Ala Ile Val Glu
                  65                  70                  75

 Pro Ser Glu Arg His Phe Tyr Gln Pro Ile Trp Thr Leu Val Gly
                  80                  85                  90

 Ala Gly Ala Lys Gln Leu Ser Ser Ser Gly Arg Pro Thr Ala Ser
                  95                 100                 105

 Val Ile Pro Ser Gly Val Glu Trp Ile Lys Ala Arg Val Thr Glu
                 110                 115                 120

 Leu Asn Pro Asp Lys Asn Cys Ile His Thr Asp Asp Asp Glu Lys
                 125                 130                 135

 Ile Ser Tyr Arg Tyr Leu Ile Ile Ala Leu Gly Ile Gln Leu Asp
                 140                 145                 150

 Tyr Glu Lys Ile Lys Gly Leu Pro Glu Gly Phe Ala His Pro Lys
                 155                 160                 165

 Ile Gly Ser Asn Tyr Ser Val Lys Thr Val Glu Lys Thr Trp Lys
                 170                 175                 180

 Ala Leu Gln Asp Phe Lys Glu Gly Asn Ala Ile Phe Thr Phe Pro
                 185                 190                 195

 Asn Thr Pro Val Lys Cys Ala Gly Ala Pro Gln Lys Ile Met Tyr
                 200                 205                 210

 Leu Ser Glu Ala Tyr Phe Arg Lys Thr Gly Lys Arg Ser Lys Ala
                 215                 220                 225

 Asn Ile Ile Phe Asn Thr Ser Leu Gly Ala Ile Phe Gly Val Lys
                 230                 235                 240

 Lys Tyr Ala Asp Ala Leu Gln Glu Ile Ile Gln Glu Arg Asn Leu
                 245                 250                 255

 Thr Val Asn Tyr Lys Lys Asn Leu Ile Glu Val Arg Ala Asp Lys
                 260                 265                 270

 Gln Glu Ala Val Phe Glu Asn Leu Asp Lys Pro Gly Glu Thr Gln
                 275                 280                 285

 Val Ile Ser Tyr Glu Met Leu His Val Thr Pro Pro Met Ser Pro
                 290                 295                 300

 Pro Asp Val Leu Lys Thr Ser Pro Val Ala Asp Ala Ala Gly Trp
                 305                 310                 315

 Val Asp Val Asp Lys Glu Thr Leu Gln His Arg Arg Tyr Pro Asn
                 320                 325                 330

 Val Phe Gly Ile Gly Asp Cys Thr Asn Leu Pro Thr Ser Lys Thr
                 335                 340                 345

 Ala Ala Ala Val Ala Ala Gln Ser Gly Ile Leu Asp Arg Thr Ile
                 350                 355                 360

 Ser Val Ile Met Lys Asn Gln Thr Pro Thr Lys Lys Tyr Asp Gly
                 365                 370                 375

 Tyr Thr Ser Cys Pro Leu Val Thr Gly Tyr Asn Arg Val Ile Leu
                 380                 385                 390

 Ala Glu Phe Asp Tyr Lys Ala Glu Pro Leu Glu Thr Phe Pro Phe
                 395                 400                 405

 Asp Gln Ser Lys Glu Arg Leu Ser Met Tyr Leu Met Lys Ala Asp
                 410                 415                 420

 Leu Met Pro Phe Leu Tyr Trp Asn Met Met Leu Arg Gly Tyr Trp
                 425                 430                 435

 Gly Gly Pro Ala Phe Leu Arg Lys Leu Phe His Leu Gly Met Ser
                 440                 445                 450

<210> 3132
<211> 1668
<212> DNA
<213> Homo sapien

<400> 3132
 ggcacgaggg tgagcgctcg caagaggacg gcagaggccc ggcagctcgg 50

 agctccggga ccttgtggcg catcaggacg cggctgtccc tctgccggga 100

 cccagagccg ccgccgccgc tctgcctcct gcgtgttagc ctcctctgcg 150

 cgctccgggc aggcggccgt gggagccgct ggggcgagga cggcgcgagg 200

 ctgctgctgc tgcccccggc ccgcgcggct ggaaacggag aggccgagcc 250

 aagcggcggc ccctcttatg ctgggaggat gctggagagt agcggctgca 300

 aagcgctgaa ggagggcgtg ctggagaagc gcagcgacgg gttgttgcag 350

 ctctggaaga aaaagtgttg catcctcacc gaggaagggc tgctgcttat 400

 cccgcccaag cagctgcaac accagcagca gcagcaacag cagcagcagc 450

 agcagcaaca acagcccggg caggggccgg ccgagccgtc ccaacccagt 500

 ggccccgctg tcgccagcct cgagccgccg gtcaagctca aggaactgca 550

 cttctccaac atgaagaccg tggactgtgt ggagcgcaag ggcaagtaca 600

 tgtacttcac tgtggtgatg gcagagggca aggagatcga ctttcggtgc 650

 ccgcaagacc agggctggaa cgccgagatc acgctgcaga tggtgcagta 700

 caagaatcgt caggccatcc tggcggtcaa atccacgcgg cagaagcagc 750

 agcacctggt ccagcagcag cccccctcgc agccgcagcc gcagccgcag 800

 ctccagcccc aaccccagcc tcagcctcag ccgcaacccc agccccaatc 850

 acaaccccag cctcagcccc aacccaagcc tcagccccag cagctccacc 900

 cgtatccgca tccacatcca catccacact ctcatcctca ctcgcaccca 950

 caccctcacc cgcacccgca tccgcaccaa ataccgcacc cacacccaca 1000

 gccgcactcg cagccgcacg ggcaccggct tctccgcagc acctccaact 1050

 ctgcctgaaa ggggcagctc ccgggcaaga caaggttttg aggacttgag 1100

 gaagtgggac gagcacattt ctattgtctt cacttggatc aaaagcaaaa 1150

 cagtctctcc gccccgcacc agatcaagta gtttggacat caccctactg 1200

 aaaacttgcg attcttctta gttttctgca tacttttcat cacgatgcag 1250

 gaaacgattt cgagtcaaga agacttttat ttatgaacct ttgaaaggat 1300

 cgtcttgtat ggtgaatttt ctaggagcga tgatgtactg taattttatt 1350

 ttaatgtatt ttgatttatg attatttatt agtttttttt aaatgcttgt 1400

 tctaagacat ttctgaatgt agaccatttt ccaaaaagga aactttattt 1450

 tcaaaaacct aatccgtagt aattcctaat cttggagaat aaaaaagggc 1500

 ggtggagggg aaaacattaa gaatttattc attatttctc gagtactttc 1550

 agaaagtctg acactttcat tgttgtgcca gctggttgaa attaaaactc 1600

 tgatattaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaa 1668

<210> 3133
<211> 259
<212> PRT
<213> Homo sapien

<400> 3133
 Met Leu Glu Ser Ser Gly Cys Lys Ala Leu Lys Glu Gly Val Leu
   1               5                  10                  15

 Glu Lys Arg Ser Asp Gly Leu Leu Gln Leu Trp Lys Lys Lys Cys
                  20                  25                  30

 Cys Ile Leu Thr Glu Glu Gly Leu Leu Leu Ile Pro Pro Lys Gln
                  35                  40                  45

 Leu Gln His Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                  50                  55                  60

 Gln Gln Pro Gly Gln Gly Pro Ala Glu Pro Ser Gln Pro Ser Gly
                  65                  70                  75

 Pro Ala Val Ala Ser Leu Glu Pro Pro Val Lys Leu Lys Glu Leu
                  80                  85                  90

 His Phe Ser Asn Met Lys Thr Val Asp Cys Val Glu Arg Lys Gly
                  95                 100                 105

 Lys Tyr Met Tyr Phe Thr Val Val Met Ala Glu Gly Lys Glu Ile
                 110                 115                 120

 Asp Phe Arg Cys Pro Gln Asp Gln Gly Trp Asn Ala Glu Ile Thr
                 125                 130                 135

 Leu Gln Met Val Gln Tyr Lys Asn Arg Gln Ala Ile Leu Ala Val
                 140                 145                 150

 Lys Ser Thr Arg Gln Lys Gln Gln His Leu Val Gln Gln Gln Pro
                 155                 160                 165

 Pro Ser Gln Pro Gln Pro Gln Pro Gln Leu Gln Pro Gln Pro Gln
                 170                 175                 180

 Pro Gln Pro Gln Pro Gln Pro Gln Pro Gln Ser Gln Pro Gln Pro
                 185                 190                 195

 Gln Pro Gln Pro Lys Pro Gln Pro Gln Gln Leu His Pro Tyr Pro
                 200                 205                 210

 His Pro His Pro His Pro His Ser His Pro His Ser His Pro His
                 215                 220                 225

 Pro His Pro His Pro His Pro His Gln Ile Pro His Pro His Pro
                 230                 235                 240

 Gln Pro His Ser Gln Pro His Gly His Arg Leu Leu Arg Ser Thr
                 245                 250                 255

 Ser Asn Ser Ala


<210> 3134
<211> 3227
<212> DNA
<213> Homo sapien

<400> 3134
 cccgtatccg catccacatc cacatccaca ctctcatcct cactcgcacc 50

 cacaccctca cccgcacccg catccgcacc aaataccgca cccacaccca 100

 cagccgcact cgcagccgca cgggcaccgg cttctccgca gcacctccaa 150

 ctctgcctga aaggggcagc tcccgggcaa gacaaggttt tgaggacttg 200

 aggaagtggg acgagcacat ttctattgtc ttcacttgga tcaaaagcaa 250

 aacagtctct ccgccccgca ccagatcaag tagtttggac atcaccctac 300

 tgaacaactt ggcgattctt cttagttttc tgcatacttt tcatcaccga 350

 tgcaggaaac gatttcgagt caagaagact tttatttatg aacctttgaa 400

 aggatcgtct tgtatggtga attttctagg agcgatgatg tactgtaatt 450

 ttattttaat gtattttgat ttatgattat ttattagttt tttttaaatg 500

 cttgttctaa gacatttctg aatgtagacc attttccaaa aaggaaactt 550

 tattttcaaa aacctaatcc gtagtaattc ctaatcttgg agaataaaaa 600

 agggcggtgg aggggaaaac attaagaatt tattcattat ttctcgagta 650

 ctttcagaaa gtctgacact ttcattgttg tgccagctgg ttgaaattaa 700

 aactctgata ttactttttt tgaggatttt tatttttgtt tttgcttaaa 750

 cactatagtt tgtctagaag tttaaaaagc taaaagttaa aaatggtgta 800

 attatgaaaa tctaacactc aagatagttt ctaaaaggaa atcagtagtt 850

 aaggatacct gatttcaaaa tatttaaagc ataacctaac tgatggtagg 900

 atgattgtat cttgaatatg tggtagggcc acatctattg taggaaaacc 950

 ttgcttttat catctgtgtg taaagggctt aataaggaga agaggccttt 1000

 tgactgattt gtgagtataa atgcatttgc tgtttcattt caaaaatgtt 1050

 gtggaggaaa agagtacatt taacttgtat aagagaatat ttgtactcct 1100

 gtccaggctg caggaccttt cttcgagagc tttgcacact tgacttgaac 1150

 cacattttct gatcccttta ctttgtttta gaagcacact gaaaaatctc 1200

 gttgtttaaa gtacaatttg taaatatttc aaaggtctag gagtcataac 1250

 ttttgttttc atactgaaaa tgatgttgat cagagaaacc aactgttttg 1300

 cttttcattg ctctgtgaga aattgaggat tctgttttgc tgttaggtaa 1350

 gctaactcag aaattgaaag gaaagactgg ataaacaccg gattttcagt 1400

 aagaaaacaa ccccagtctt gtcttagaag ccacttgttg aggagtctgt 1450

 tgggggaaaa aagaggatat gcttttaaag gtagaacaaa ccttcttctg 1500

 tgttaaatca aaaggatgtt caaaatccac caggacagat gctacttggg 1550

 tttaaatgga gccatagatg atacaaagtc ctcttggggc tgaaaatcac 1600

 ttcctatttg catggcttta ctaactggtt tctgttttcc attatctttt 1650

 tcacagaaag tcttggtcag tatttttcca gcatttaaat tgaaacggtc 1700

 agtattagac cactgctagg ttatgtagtc aagaaataaa aatagaatta 1750

 catgctacag atgtctttat tctccttcca tctagaaagg agttccaagg 1800

 tcaaattact ttttagtgca atagttaaat gacattttga gatcataact 1850

 catatccaaa aagttgcagg gaaaattaaa atagctttcc cctattaagc 1900

 taatggcaaa caaaacttaa gtggaccccc acttccagtg gttgtttagg 1950

 ttgcagttgt gaaaatatgc tgccaacatt taaaaacttg tttcatatgt 2000

 atatatgtat acacatatat gaatatgtat gtatatatac atatatgaga 2050

 acatgtgtgt acacatatat gaatatgtat atatgtgtat gtatgtatat 2100

 atgtatatga aatgagagcc acatctaaag atttcttaaa tcaagtttgg 2150

 ttcagcttcc ttagaactgt ggctgtactt tttgaggagt acctcatagt 2200

 actatatttt taatgcatgc aaatcataat agctccaaat gaaccacagt 2250

 tttttcccaa tggaggattt ttttttaatt cttgtactaa aaaaaaaaaa 2300

 tccataccaa atatttttac aaattaagat tgatgtaggt tttaaaaaag 2350

 gcatttgtat gttgttagct tacatatggg gctaggtaat ttcattgctt 2400

 aaaaagatgc gcctaggctc cctcttggtg gctggatttc tttttcttcg 2450

 cccgtggtgg ccatggtttt taatagggcc accggaatca tggtttcttt 2500

 tttttttttt tttttggaga tggagtctcg ccctgtgacc caggctggag 2550

 tgcagtggca cgatctcggc tcactgcaac ctctgcctct tgggttcacg 2600

 ccattctcct gtgtcagcct cctgagtagc tgggactaca ggtgaatgcc 2650

 accacgcccg gctgattttt gtatttttag tagagatggg gtttcaccat 2700

 agtggtcagg ctgttctcga actcctgacc tcaggtgatc cacctgcctt 2750

 ggcctcccaa agtgctagga ttacaggtgt gagccaccac acccggcccc 2800

 agagtaatgg tttcttgact ttctgtagcc cttgttcctt agtctgctgt 2850

 gatatttatg ttgaccttta tcattttcta ttctgaaccc ctcttagcat 2900

 ttaatgtgaa atctaagaaa ttagaagtag aatggctttt attgttttga 2950

 cacctttgaa attattatta ataatttttc cagagcaaaa aagcaaacac 3000

 gctcaataag actaaacaaa acaaaatata aatgtacatc atttaatgtc 3050

 ccagtggctc tattctacct gtaagaaaat gatacaaaac cacctaagat 3100

 attttgaagc ctgacaaatc agcttcatgg aaaaaggtaa aaaatgcatt 3150

 tttcaaccga aagggcagat ccaatagaag acccgctcct taaataaaca 3200

 taaaatgtaa aaagttggaa aaaaaaa 3227

<210> 3135
<211> 1412
<212> DNA
<213> Homo sapien

<400> 3135
 ctccttgggc gatcgcctgg gtagaggaga ggagtttccg gggctcgggt 50

 ccgggtcgcc ttccagggga acgagcgcgg aagcaagtgg gcggcgagag 100

 gcggagcaag agacgctgga gggcgtggac gcagcgggct ttggaaaggc 150

 cccaagttaa tgaggcgtgc gccggctgcc gagcgcctct tggagctggg 200

 ctttcccccg cggtgcgggc gccaggagcc gccttttccg ctgggtgtca 250

 ctcgggggtg gggaagatgg cccattcaaa agcgccgcga gggggcccgg 300

 ccagtgccct tcagtgagcg ctcgcaagag gacggcagag gcccggcagc 350

 tcggagctcc gggaccttgt ggcgcatcag gacgcggctg tccctctgcc 400

 gggacccaga gccgccgccg ccgctctgcc tcctgcgtgt tagcctcctc 450

 tgcgcgctcc gggcaggcgg ccgtgggagc cgctggggcg aggacggcgc 500

 gaggctgctg ctgctgcccc cggcccgcgc ggctggaaac ggagaggccg 550

 agccaagcgg cggcccctct tatgctggga ggatgctgga gagtagcggc 600

 tgcaaagcgc tgaaggaggg cgtgctggag aagcgcagcg acgggttgtt 650

 gcagctctgg aagaaaaagt gttgcatcct caccgaggaa gggctgctgc 700

 ttatcccgcc caagcagctg caacaccagc agcagcagca acagcagcag 750

 cagcagcagc aacaacagcc cgggcagggg ccggccgagc cgtcccaacc 800

 cagtggcccc gctgtcgcca gcctcgagcc gccggtcaag ctcaaggaac 850

 tgcacttctc caacatgaag accgtggact gtgtggagcg caagggcaag 900

 tacatgtact tcactgtggt gatggcagag ggcaaggaga tcgactttcg 950

 gtgcccgcaa gaccagggct ggaacgccga gatcacgctg cagatggtgc 1000

 agtacaagaa tcgtcaggcc atcctggcgg tcaaatccac gcggcagaag 1050

 cagcagcacc tggtccagca gcagcccccc tcgcagccgc agccgcagcc 1100

 gcagctccag ccccaacccc agcctcagcc tcagccgcaa ccccagcccc 1150

 aatcacaacc ccagcctcag ccccaaccca agcctcagcc ccagcagctc 1200

 cacccgtatc cgcatccaca tccacatcca cactctcatc ctcactcgca 1250

 cccacaccct cacccgcacc cgcatccgca ccaaataccg cacccacacc 1300

 cacagccgca ctcgcagccg cacgggcacc ggcttctccg cagcacctcc 1350

 aactctgcct gaaaggggca gctcccgggc aagacaaggt tttgaggact 1400

 tgaggaagtg gg 1412

<210> 3136
<211> 400
<212> PRT
<213> Homo sapien

<400> 3136
 Met Arg Arg Ala Pro Ala Ala Glu Arg Leu Leu Glu Leu Gly Phe
   1               5                  10                  15

 Pro Pro Arg Cys Gly Arg Gln Glu Pro Pro Phe Pro Leu Gly Val
                  20                  25                  30

 Thr Arg Gly Trp Gly Arg Trp Pro Ile Gln Lys Arg Arg Glu Gly
                  35                  40                  45

 Ala Arg Pro Val Pro Phe Ser Glu Arg Ser Gln Glu Asp Gly Arg
                  50                  55                  60

 Gly Pro Ala Ala Arg Ser Ser Gly Thr Leu Trp Arg Ile Arg Thr
                  65                  70                  75

 Arg Leu Ser Leu Cys Arg Asp Pro Glu Pro Pro Pro Pro Leu Cys
                  80                  85                  90

 Leu Leu Arg Val Ser Leu Leu Cys Ala Leu Arg Ala Gly Gly Arg
                  95                 100                 105

 Gly Ser Arg Trp Gly Glu Asp Gly Ala Arg Leu Leu Leu Leu Pro
                 110                 115                 120

 Pro Ala Arg Ala Ala Gly Asn Gly Glu Ala Glu Pro Ser Gly Gly
                 125                 130                 135

 Pro Ser Tyr Ala Gly Arg Met Leu Glu Ser Ser Gly Cys Lys Ala
                 140                 145                 150

 Leu Lys Glu Gly Val Leu Glu Lys Arg Ser Asp Gly Leu Leu Gln
                 155                 160                 165

 Leu Trp Lys Lys Lys Cys Cys Ile Leu Thr Glu Glu Gly Leu Leu
                 170                 175                 180

 Leu Ile Pro Pro Lys Gln Leu Gln His Gln Gln Gln Gln Gln Gln
                 185                 190                 195

 Gln Gln Gln Gln Gln Gln Gln Gln Pro Gly Gln Gly Pro Ala Glu
                 200                 205                 210

 Pro Ser Gln Pro Ser Gly Pro Ala Val Ala Ser Leu Glu Pro Pro
                 215                 220                 225

 Val Lys Leu Lys Glu Leu His Phe Ser Asn Met Lys Thr Val Asp
                 230                 235                 240

 Cys Val Glu Arg Lys Gly Lys Tyr Met Tyr Phe Thr Val Val Met
                 245                 250                 255

 Ala Glu Gly Lys Glu Ile Asp Phe Arg Cys Pro Gln Asp Gln Gly
                 260                 265                 270

 Trp Asn Ala Glu Ile Thr Leu Gln Met Val Gln Tyr Lys Asn Arg
                 275                 280                 285

 Gln Ala Ile Leu Ala Val Lys Ser Thr Arg Gln Lys Gln Gln His
                 290                 295                 300

 Leu Val Gln Gln Gln Pro Pro Ser Gln Pro Gln Pro Gln Pro Gln
                 305                 310                 315

 Leu Gln Pro Gln Pro Gln Pro Gln Pro Gln Pro Gln Pro Gln Pro
                 320                 325                 330

 Gln Ser Gln Pro Gln Pro Gln Pro Gln Pro Lys Pro Gln Pro Gln
                 335                 340                 345

 Gln Leu His Pro Tyr Pro His Pro His Pro His Pro His Ser His
                 350                 355                 360

 Pro His Ser His Pro His Pro His Pro His Pro His Pro His Gln
                 365                 370                 375

 Ile Pro His Pro His Pro Gln Pro His Ser Gln Pro His Gly His
                 380                 385                 390

 Arg Leu Leu Arg Ser Thr Ser Asn Ser Ala
                 395                 400

<210> 3137
<211> 523
<212> DNA
<213> Homo sapien

<400> 3137
 gcagatcgct tgcagcttgc tagctgtgtg ggctgggagg tctggtaggg 50

 ctgagcttgc aagaggatca acatgccttt ggctagagat ttactacatc 100

 cgtccttgga agaggaaaag aaaaaacata aaaagaaacg cctagtacaa 150

 agtccaaatt cttactttat ggatgtaaaa tgtccaggtt gctacaagat 200

 caccacggtt ttcagccatg ctcagacagt ggttctttgt gtaggttgtt 250

 caacagtgtt gtgccagcct acaggaggaa aggccagact cacagaaggg 300

 tgttcattta gaagaaagca acactaatga ttcaaacagc ttcctgaatt 350

 ttaattttgt gttgtctcac agaaagcctt atcataaatt ccataattct 400

 aattaattta ccaagataat gtaattacat ttggttttgt aaggtataca 450

 gcagtaatct cctattttgg tgtcagtttt tcaataaagt tttgattatg 500

 ggcaaaaaaa aaaaaaaaaa aaa 523

<210> 3138
<211> 84
<212> PRT
<213> Homo sapien

<400> 3138
 Met Pro Leu Ala Arg Asp Leu Leu His Pro Ser Leu Glu Glu Glu
   1               5                  10                  15

 Lys Lys Lys His Lys Lys Lys Arg Leu Val Gln Ser Pro Asn Ser
                  20                  25                  30

 Tyr Phe Met Asp Val Lys Cys Pro Gly Cys Tyr Lys Ile Thr Thr
                  35                  40                  45

 Val Phe Ser His Ala Gln Thr Val Val Leu Cys Val Gly Cys Ser
                  50                  55                  60

 Thr Val Leu Cys Gln Pro Thr Gly Gly Lys Ala Arg Leu Thr Glu
                  65                  70                  75

 Gly Cys Ser Phe Arg Arg Lys Gln His
                  80

<210> 3139
<211> 3044
<212> DNA
<213> Homo sapien

<400> 3139
 gtttgcgggt ggttgttgct ctcggggccg tgtggagtag gtctggacct 50

 ggactcacgg ctgcttggag cgtccgccat gaggagaagt gaggtgctgg 100

 cggaggagtc catagtatgt ctgcagaaag ccctaaatca ccttcgggaa 150

 atatgggagc taattgggat tccagaggac cagcggttac aaagaactga 200

 ggtggtaaag aagcatatca aggaactcct ggatatgatg attgctgaag 250

 aggaaagcct gaaggaaaga ctcatcaaaa gcatatccgt ctgtcagaaa 300

 gagctgaaca ctctgtgcag cgagttacat gttgagccat ttcaggaaga 350

 aggagagacg accatcttgc aactagaaaa agatttgcgc acccaagtgg 400

 aattgatgcg aaaacagaaa aaggagagaa aacaggaact gaagctactt 450

 caagagcaag atcaagaact gtgcgaaatt ctttgtatgc cccactatga 500

 tattgacagt gcctcagtgc ccagcttaga agagctgaac cagttcaggc 550

 aacatgtgac aactttgagg gaaacaaagg cttctaggcg tgaggagttt 600

 gtcagtataa agagacagat catactgtgt atggaagaat tagaccacac 650

 cccagacaca agctttgaaa gagatgtggt gtgtgaagac gaagatgcct 700

 tttgtttgtc tttggagaat attgcaacac tacaaaagtt gctacggcag 750

 ctggaaatgc agaaatcaca aaatgaagca gtgtgtgagg ggctgcgtac 800

 tcaaatccga gagctctggg acaggttgca aatacctgaa gaagaaagag 850

 aagctgtggc caccattatg tctgggtcaa aggccaaggt ccggaaagcg 900

 ctgcaattag aagtggatcg gttggaagaa ctgaaaatgc aaaacatgaa 950

 gaaagtgatt gaggcaattc gagtggagct ggttcagtac tgggaccagt 1000

 gcttttatag ccaggagcag agacaagctt ttgccccttt ctgtgctgag 1050

 gactacacag aaagtctgct ccagctccac gatgctgaga ttgtgcggtt 1100

 aaaaaactac tatgaagttc acaaggaact ctttgaaggt gtccagaagt 1150

 gggaagaaac ctggaggctt ttcttagagt ttgagagaaa agcttcagat 1200

 ccaaatcgat ttacaaaccg aggaggaaat cttctaaaag aagaaaaaca 1250

 acgagccaag ctccagaaaa tgctgcccaa gctggaagaa gagttgaagg 1300

 cacgaattga attgtgggaa caggaacatt caaaggcatt tatggtgaat 1350

 gggcagaaat tcatggagta tgtggcagaa caatgggaga tgcatcgatt 1400

 ggagaaagag agagccaagc aggaaagaca actgaagaac aaaaaacaga 1450

 cagagacaga gatgctgtat ggcagcgctc ctcgaacacc tagcaagcgg 1500

 cgaggactgg ctcccaatac accgggcaaa gcacgtaagc tgaacactac 1550

 caccatgtcc aatgctacgg ccaatagtag cattcggcct atctttggag 1600

 ggacagtcta ccactccccc gtgtctcgac ttcctccttc tggcagcaag 1650

 ccagtcgctg cttccacctg ttcagggaag aaaacacccc gtactggcag 1700

 gcatggagcc aacaaggaga acctggagct caacggcagc atcctgagtg 1750

 gtgggtaccc tggctcggcc cccctccagc gcaacttcag cattaattct 1800

 gttgccagca cctattctga gtttgcgaag gatccgtccc tctctgacag 1850

 ttccactgtt gggcttcagc gagaactttc aaaggcttcc aaatctgatg 1900

 ctacttctgg aatcctcaat tcaaccaaca tccagtcctg agaagccctg 1950

 atcagtcaac cagctgtggc ttcctgtgcc tagactggac ctaattatat 2000

 gggggtgact ttagtttttc ttcagcttag gagtgcttga aaccttggcc 2050

 aggttccatg accatgggcc taacttaaag atgtgaatga gtgttacagt 2100

 tgaaagccca tcataggttt agtggtccta ggagacttgg ttttgactta 2150

 tatacatgaa aagtttatgg caagaagtgc aaattttagc atatggggcc 2200

 tgacttctct accacataat tctacttgct gaagcatgat caaagcttgt 2250

 tttatttcac cactgtagga aaatgattga ctatgcccat ccctgggggt 2300

 aattttggca tgtatacctg taactagtaa ttaacatctt ttttgtttag 2350

 gcatgttcaa ttaatgctgt agctatcata gctttgctct tacctgaagc 2400

 cttgtcccca ccacacagga cagccttcct cctgaagaga atgtctttgt 2450

 gtgtccgaag ttgagatggc ctgccctact ggcaaagagg tgacaggaag 2500

 gctgggagca gctttgttaa attgtgttca gttctgttac acagtgcatt 2550

 gccctttgtt gggggtatgc atgtatgaac acacatgctt gtcggaacgc 2600

 tttctcggcg tttgtccctt ggctctcatc tcccccattc ctgtgcctac 2650

 tttgcctgag ttcttctacc cccgcagttg ccagccagat tgggagtctg 2700

 tttgttccaa tgggttgagc tgtctttgtc gtggagatct ggaactttgc 2750

 acatgtcact actggggagg tgttcctgct ctagcttcca cgatgaggcg 2800

 ccctctttac ctatcctctc aatcactact cttcttgaag cactattatt 2850

 tattcttccg ctgtctgcct gcagcagtac tactgtcaac atagtgtaaa 2900

 tggttctcaa aagcttacca gtgtggactt ggtgttagcc acgctgttta 2950

 cctcatacag tacgtgtcct gtttttaaaa tatacaatta ttcttaaaaa 3000

 taaattaaaa tcgtatactt acatttcaaa aaaaaaaaaa aaaa 3044

<210> 3140
<211> 620
<212> PRT
<213> Homo sapien

<400> 3140
 Met Arg Arg Ser Glu Val Leu Ala Glu Glu Ser Ile Val Cys Leu
   1               5                  10                  15

 Gln Lys Ala Leu Asn His Leu Arg Glu Ile Trp Glu Leu Ile Gly
                  20                  25                  30

 Ile Pro Glu Asp Gln Arg Leu Gln Arg Thr Glu Val Val Lys Lys
                  35                  40                  45

 His Ile Lys Glu Leu Leu Asp Met Met Ile Ala Glu Glu Glu Ser
                  50                  55                  60

 Leu Lys Glu Arg Leu Ile Lys Ser Ile Ser Val Cys Gln Lys Glu
                  65                  70                  75

 Leu Asn Thr Leu Cys Ser Glu Leu His Val Glu Pro Phe Gln Glu
                  80                  85                  90

 Glu Gly Glu Thr Thr Ile Leu Gln Leu Glu Lys Asp Leu Arg Thr
                  95                 100                 105

 Gln Val Glu Leu Met Arg Lys Gln Lys Lys Glu Arg Lys Gln Glu
                 110                 115                 120

 Leu Lys Leu Leu Gln Glu Gln Asp Gln Glu Leu Cys Glu Ile Leu
                 125                 130                 135

 Cys Met Pro His Tyr Asp Ile Asp Ser Ala Ser Val Pro Ser Leu
                 140                 145                 150

 Glu Glu Leu Asn Gln Phe Arg Gln His Val Thr Thr Leu Arg Glu
                 155                 160                 165

 Thr Lys Ala Ser Arg Arg Glu Glu Phe Val Ser Ile Lys Arg Gln
                 170                 175                 180

 Ile Ile Leu Cys Met Glu Glu Leu Asp His Thr Pro Asp Thr Ser
                 185                 190                 195

 Phe Glu Arg Asp Val Val Cys Glu Asp Glu Asp Ala Phe Cys Leu
                 200                 205                 210

 Ser Leu Glu Asn Ile Ala Thr Leu Gln Lys Leu Leu Arg Gln Leu
                 215                 220                 225

 Glu Met Gln Lys Ser Gln Asn Glu Ala Val Cys Glu Gly Leu Arg
                 230                 235                 240

 Thr Gln Ile Arg Glu Leu Trp Asp Arg Leu Gln Ile Pro Glu Glu
                 245                 250                 255

 Glu Arg Glu Ala Val Ala Thr Ile Met Ser Gly Ser Lys Ala Lys
                 260                 265                 270

 Val Arg Lys Ala Leu Gln Leu Glu Val Asp Arg Leu Glu Glu Leu
                 275                 280                 285

 Lys Met Gln Asn Met Lys Lys Val Ile Glu Ala Ile Arg Val Glu
                 290                 295                 300

 Leu Val Gln Tyr Trp Asp Gln Cys Phe Tyr Ser Gln Glu Gln Arg
                 305                 310                 315

 Gln Ala Phe Ala Pro Phe Cys Ala Glu Asp Tyr Thr Glu Ser Leu
                 320                 325                 330

 Leu Gln Leu His Asp Ala Glu Ile Val Arg Leu Lys Asn Tyr Tyr
                 335                 340                 345

 Glu Val His Lys Glu Leu Phe Glu Gly Val Gln Lys Trp Glu Glu
                 350                 355                 360

 Thr Trp Arg Leu Phe Leu Glu Phe Glu Arg Lys Ala Ser Asp Pro
                 365                 370                 375

 Asn Arg Phe Thr Asn Arg Gly Gly Asn Leu Leu Lys Glu Glu Lys
                 380                 385                 390

 Gln Arg Ala Lys Leu Gln Lys Met Leu Pro Lys Leu Glu Glu Glu
                 395                 400                 405

 Leu Lys Ala Arg Ile Glu Leu Trp Glu Gln Glu His Ser Lys Ala
                 410                 415                 420

 Phe Met Val Asn Gly Gln Lys Phe Met Glu Tyr Val Ala Glu Gln
                 425                 430                 435

 Trp Glu Met His Arg Leu Glu Lys Glu Arg Ala Lys Gln Glu Arg
                 440                 445                 450

 Gln Leu Lys Asn Lys Lys Gln Thr Glu Thr Glu Met Leu Tyr Gly
                 455                 460                 465

 Ser Ala Pro Arg Thr Pro Ser Lys Arg Arg Gly Leu Ala Pro Asn
                 470                 475                 480

 Thr Pro Gly Lys Ala Arg Lys Leu Asn Thr Thr Thr Met Ser Asn
                 485                 490                 495

 Ala Thr Ala Asn Ser Ser Ile Arg Pro Ile Phe Gly Gly Thr Val
                 500                 505                 510

 Tyr His Ser Pro Val Ser Arg Leu Pro Pro Ser Gly Ser Lys Pro
                 515                 520                 525

 Val Ala Ala Ser Thr Cys Ser Gly Lys Lys Thr Pro Arg Thr Gly
                 530                 535                 540

 Arg His Gly Ala Asn Lys Glu Asn Leu Glu Leu Asn Gly Ser Ile
                 545                 550                 555

 Leu Ser Gly Gly Tyr Pro Gly Ser Ala Pro Leu Gln Arg Asn Phe
                 560                 565                 570

 Ser Ile Asn Ser Val Ala Ser Thr Tyr Ser Glu Phe Ala Lys Asp
                 575                 580                 585

 Pro Ser Leu Ser Asp Ser Ser Thr Val Gly Leu Gln Arg Glu Leu
                 590                 595                 600

 Ser Lys Ala Ser Lys Ser Asp Ala Thr Ser Gly Ile Leu Asn Ser
                 605                 610                 615

 Thr Asn Ile Gln Ser
                 620

<210> 3141
<211> 2589
<212> DNA
<213> Homo sapien

<400> 3141
 agcaacatgg ccgccgcctg agaggagagc cgggccgccg ccgtctctgc 50

 agcccgcggg taactgggcc gttgccgccg tccgcgctcg gcccccgcgg 100

 agagatcgag ctgaaggact gcgcggctgg ctctcctcta gtatggccaa 150

 tgaagaggat gacccagttg tacaggagat cgatgtgtac ttggccaaga 200

 gtctggcgga aaagctgtat ctatttcagt accctgtgcg tccagcctcg 250

 atgacctacg atgacattcc gcacctctca gccaagatca agcccaagca 300

 gcagaaggta gagcttgaga tggccatcga caccctgaac cccaactatt 350

 gccgcagcaa aggggagcag attgcgctga acgtggacgg ggcctgcgcc 400

 gacgagacca gcacgtattc ctcgaagctg atggacaagc agaccttctg 450

 ctcttcccag accaccagta acacatcccg ttatgccgct gcactctaca 500

 ggcaaggtga gctccacctg acacctttac atggcatcct gcagctgcgg 550

 cccagcttct cctacctgga taaggctgac gccaagcacc gggagaggga 600

 ggcggccaac gaggcagggg actcttcaca ggatgaggcg gaagacgatg 650

 ttaagcagat cacggtgcgg ttctcccggc cggagtcaga gcaggcccgc 700

 cagcgccgtg tgcagtccta tgagttcctg cagaagaagc acgcagagga 750

 gccctgggtc cacctgcatt actatggcct gagggacagt cgctctgagc 800

 atgagcgtca gtacctgctg tgccccggct caagcggggt ggagaacacg 850

 gagctcgtca agtcacccag tgagtacctg atgatgctga tgccacccag 900

 ccaggaggag gagaaagaca agcctgtggc ccccagcaac gtcctgtcga 950

 tggcccagct gcgcacgctg cccctggccg atcagatcaa gatcctgatg 1000

 aagaatgtga aggtcatgcc ttttgccaac ttgatgagcc tcctgggccc 1050

 ctccatcgat tccgtggctg ttctgcgggg catccagaag gtggcgatgt 1100

 tggtccaagg gaactgggtg gtgaagagtg acatcctata ccccaaggac 1150

 tcgtccagcc ctcacagcgg cgtgcctgct gaggtgctct gcaggggccg 1200

 agacttcgtt atgtggaagt tcacgcagag ccgctgggtg gttaggaaag 1250

 aggtggcaac cgtgaccaaa ctctgcgccg aggatgtgaa ggacttcctg 1300

 gagcacatgg ccgtggtgag gatcaacaaa ggctgggagt tcattctgcc 1350

 ttatgatggg gagttcatca agaagcaccc ggatgtggtc cagcggcagc 1400

 acatgctgtg gacgggtatc caggccaaac tggaaaaagt ctataatctt 1450

 gtaaaggaaa ccatgccaaa gaagccggat gcacaatcag ggcctgccgg 1500

 gctggtctgt ggggaccagc ggatccaagt agccaaaacc aaggcccagc 1550

 agaaccacgc gttgctggag cgggagctgc agcggcggaa ggagcagctg 1600

 cgggtgcctg cggtcccgcc cggtgtgcgg atcaaggagg agcccgtgag 1650

 cgaggagggc gaggaggacg aggagcagga ggcggaggag gagcccatgg 1700

 acacttcccc cagcggcctc cacagcaagc tggccaacgg gctgcctctc 1750

 gggcgggctg cgggcacaga cagcttcaac gggcacccgc cccagggctg 1800

 cgccagcacc cctgtggctc gggaactgaa ggccttcgtg gaggccacct 1850

 ttcagagaca gtttgtgctc acgctgagcg aactcaagcg cctcttcaat 1900

 ctgcacttgg ccagcctgcc ccccggccac acactcttca gcggcatctc 1950

 ggaccgcatg ctacaggaca cggtgctggc cgccggttgc aagcagatac 2000

 tggtgccttt tcccccccag actgctgctt ccccggatga gcagaaggtg 2050

 tttgccctct gggagtctgg agacatgagt gatcagcatc gacaggtttt 2100

 gcttgaaatt ttttccaaaa attaccgggt acgccgaaac atgatccagt 2150

 ctcggttgac tcaagagtgt ggagaagatc tcagtaaaca ggaggtggat 2200

 aaagtactaa aggactgctg tgtaagctat ggtggcatgt ggtaccttaa 2250

 agggacagta cagtcttgac aatagtagca aactactaac ccagcaaatc 2300

 taagcccaag gaagaagggc ggaaccagaa gtagggcctc gacttgcttc 2350

 agacgacaca gagcaagagg aactgaccat ctcatgacct gtggcattgc 2400

 acggtgcagt ggacagaagg gattatcctc agccagtcgc agggtcagct 2450

 taagttagtt agatcactcc cagaagagac cagctgggac cttctttgca 2500

 gtacaatttg aaattcctga tgtattttgc ttattatttg gtttcattcc 2550

 cataataaag agagtgtata ctgacatggg caggatgat 2589

<210> 3142
<211> 708
<212> PRT
<213> Homo sapien

<400> 3142
 Met Ala Asn Glu Glu Asp Asp Pro Val Val Gln Glu Ile Asp Val
   1               5                  10                  15

 Tyr Leu Ala Lys Ser Leu Ala Glu Lys Leu Tyr Leu Phe Gln Tyr
                  20                  25                  30

 Pro Val Arg Pro Ala Ser Met Thr Tyr Asp Asp Ile Pro His Leu
                  35                  40                  45

 Ser Ala Lys Ile Lys Pro Lys Gln Gln Lys Val Glu Leu Glu Met
                  50                  55                  60

 Ala Ile Asp Thr Leu Asn Pro Asn Tyr Cys Arg Ser Lys Gly Glu
                  65                  70                  75

 Gln Ile Ala Leu Asn Val Asp Gly Ala Cys Ala Asp Glu Thr Ser
                  80                  85                  90

 Thr Tyr Ser Ser Lys Leu Met Asp Lys Gln Thr Phe Cys Ser Ser
                  95                 100                 105

 Gln Thr Thr Ser Asn Thr Ser Arg Tyr Ala Ala Ala Leu Tyr Arg
                 110                 115                 120

 Gln Gly Glu Leu His Leu Thr Pro Leu His Gly Ile Leu Gln Leu
                 125                 130                 135

 Arg Pro Ser Phe Ser Tyr Leu Asp Lys Ala Asp Ala Lys His Arg
                 140                 145                 150

 Glu Arg Glu Ala Ala Asn Glu Ala Gly Asp Ser Ser Gln Asp Glu
                 155                 160                 165

 Ala Glu Asp Asp Val Lys Gln Ile Thr Val Arg Phe Ser Arg Pro
                 170                 175                 180

 Glu Ser Glu Gln Ala Arg Gln Arg Arg Val Gln Ser Tyr Glu Phe
                 185                 190                 195

 Leu Gln Lys Lys His Ala Glu Glu Pro Trp Val His Leu His Tyr
                 200                 205                 210

 Tyr Gly Leu Arg Asp Ser Arg Ser Glu His Glu Arg Gln Tyr Leu
                 215                 220                 225

 Leu Cys Pro Gly Ser Ser Gly Val Glu Asn Thr Glu Leu Val Lys
                 230                 235                 240

 Ser Pro Ser Glu Tyr Leu Met Met Leu Met Pro Pro Ser Gln Glu
                 245                 250                 255

 Glu Glu Lys Asp Lys Pro Val Ala Pro Ser Asn Val Leu Ser Met
                 260                 265                 270

 Ala Gln Leu Arg Thr Leu Pro Leu Ala Asp Gln Ile Lys Ile Leu
                 275                 280                 285

 Met Lys Asn Val Lys Val Met Pro Phe Ala Asn Leu Met Ser Leu
                 290                 295                 300

 Leu Gly Pro Ser Ile Asp Ser Val Ala Val Leu Arg Gly Ile Gln
                 305                 310                 315

 Lys Val Ala Met Leu Val Gln Gly Asn Trp Val Val Lys Ser Asp
                 320                 325                 330

 Ile Leu Tyr Pro Lys Asp Ser Ser Ser Pro His Ser Gly Val Pro
                 335                 340                 345

 Ala Glu Val Leu Cys Arg Gly Arg Asp Phe Val Met Trp Lys Phe
                 350                 355                 360

 Thr Gln Ser Arg Trp Val Val Arg Lys Glu Val Ala Thr Val Thr
                 365                 370                 375

 Lys Leu Cys Ala Glu Asp Val Lys Asp Phe Leu Glu His Met Ala
                 380                 385                 390

 Val Val Arg Ile Asn Lys Gly Trp Glu Phe Ile Leu Pro Tyr Asp
                 395                 400                 405

 Gly Glu Phe Ile Lys Lys His Pro Asp Val Val Gln Arg Gln His
                 410                 415                 420

 Met Leu Trp Thr Gly Ile Gln Ala Lys Leu Glu Lys Val Tyr Asn
                 425                 430                 435

 Leu Val Lys Glu Thr Met Pro Lys Lys Pro Asp Ala Gln Ser Gly
                 440                 445                 450

 Pro Ala Gly Leu Val Cys Gly Asp Gln Arg Ile Gln Val Ala Lys
                 455                 460                 465

 Thr Lys Ala Gln Gln Asn His Ala Leu Leu Glu Arg Glu Leu Gln
                 470                 475                 480

 Arg Arg Lys Glu Gln Leu Arg Val Pro Ala Val Pro Pro Gly Val
                 485                 490                 495

 Arg Ile Lys Glu Glu Pro Val Ser Glu Glu Gly Glu Glu Asp Glu
                 500                 505                 510

 Glu Gln Glu Ala Glu Glu Glu Pro Met Asp Thr Ser Pro Ser Gly
                 515                 520                 525

 Leu His Ser Lys Leu Ala Asn Gly Leu Pro Leu Gly Arg Ala Ala
                 530                 535                 540

 Gly Thr Asp Ser Phe Asn Gly His Pro Pro Gln Gly Cys Ala Ser
                 545                 550                 555

 Thr Pro Val Ala Arg Glu Leu Lys Ala Phe Val Glu Ala Thr Phe
                 560                 565                 570

 Gln Arg Gln Phe Val Leu Thr Leu Ser Glu Leu Lys Arg Leu Phe
                 575                 580                 585

 Asn Leu His Leu Ala Ser Leu Pro Pro Gly His Thr Leu Phe Ser
                 590                 595                 600

 Gly Ile Ser Asp Arg Met Leu Gln Asp Thr Val Leu Ala Ala Gly
                 605                 610                 615

 Cys Lys Gln Ile Leu Val Pro Phe Pro Pro Gln Thr Ala Ala Ser
                 620                 625                 630

 Pro Asp Glu Gln Lys Val Phe Ala Leu Trp Glu Ser Gly Asp Met
                 635                 640                 645

 Ser Asp Gln His Arg Gln Val Leu Leu Glu Ile Phe Ser Lys Asn
                 650                 655                 660

 Tyr Arg Val Arg Arg Asn Met Ile Gln Ser Arg Leu Thr Gln Glu
                 665                 670                 675

 Cys Gly Glu Asp Leu Ser Lys Gln Glu Val Asp Lys Val Leu Lys
                 680                 685                 690

 Asp Cys Cys Val Ser Tyr Gly Gly Met Trp Tyr Leu Lys Gly Thr
                 695                 700                 705

 Val Gln Ser


<210> 3143
<211> 1300
<212> DNA
<213> Homo sapien

<400> 3143
 aacttttaaa aactctcatt ggagtaagtc ttttcaagat gatcctccac 50

 aatggaggca gcgttcctac ttgtcatcac acagctgaag acattgtttc 100

 ttaggtgtga aatcggggac aaaggacaaa cagagacaca cggcattgtt 150

 catgggaggc atcgtcaccc tcctgggtgt tctgtgggaa tttcctgtgt 200

 gaggaaaacg tggccacagg gttgtgctgt acccaccctt ccccggcgag 250

 atggccctcg gcctgtgccg ctgcttccac cctcgccact ccatggcagc 300

 ttttggtctg tttccggctc tgccctctgc cctgaactct catccggctt 350

 gtacctgcct gctggacccc tccacctgga ggccagccca tgtctcaggc 400

 ccagccctag cctcttctcc tcaaattcta agtgttttct ctttaggttt 450

 ccctggcttt gtgaatggat catgtgtctc taggtataaa cctgacatca 500

 tctttccacc cggcttacct ccaccagatc tccccagttc tgtctccatc 550

 ttctgcctgc agctgctctg ttctcatggt cactgctgca tcactgagtc 600

 tggacccttg ttatcatttt caaactggcc tccttccctc gttccccact 650

 tcttaaagtc acctgtccat tgccaccaga ttaagctttc tccagccaga 700

 tcacctctct ctgagaaacc tccattgaca tggaaacacc attgtctggc 750

 acacatactc acatacccac cttcccgtct tgatccccac acatctttcc 800

 agcctcccct cccactccac tccctgctct ctcctccacc tccccatcct 850

 cttgtctccc ctcccctctg aatccagccc agcggggctt ctcctgcctc 900

 catcacatca cagaagtacc tcctgcttct ggttttaatt agagccttcc 950

 ccgattacat tttcctctga attttttcct atctacattt gatctgtcat 1000

 gtttaaaccc cctacttcta agggaacttc tctaatctct tatcctcatc 1050

 cccaaatagt gttttcttcc tctgggttct tataatgttg gtatcaatct 1100

 cacagcattt agtgcttcct gcctggtgtg acagttacct gtgtgcatgt 1150

 gcaatttcta atttcccacg ctagactgtg agcttcctaa ggcaagaatc 1200

 atgcctcgtt ggtttctgta ttcctcatgg tgccaaacac agtgccttct 1250

 acattgcagg cgctgaataa acatttttaa agcaaaaaaa aaaaaaaaaa 1300

<210> 3144
<211> 206
<212> PRT
<213> Homo sapien

<400> 3144
 Met Ala Leu Gly Leu Cys Arg Cys Phe His Pro Arg His Ser Met
   1               5                  10                  15

 Ala Ala Phe Gly Leu Phe Pro Ala Leu Pro Ser Ala Leu Asn Ser
                  20                  25                  30

 His Pro Ala Cys Thr Cys Leu Leu Asp Pro Ser Thr Trp Arg Pro
                  35                  40                  45

 Ala His Val Ser Gly Pro Ala Leu Ala Ser Ser Pro Gln Ile Leu
                  50                  55                  60

 Ser Val Phe Ser Leu Gly Phe Pro Gly Phe Val Asn Gly Ser Cys
                  65                  70                  75

 Val Ser Arg Tyr Lys Pro Asp Ile Ile Phe Pro Pro Gly Leu Pro
                  80                  85                  90

 Pro Pro Asp Leu Pro Ser Ser Val Ser Ile Phe Cys Leu Gln Leu
                  95                 100                 105

 Leu Cys Ser His Gly His Cys Cys Ile Thr Glu Ser Gly Pro Leu
                 110                 115                 120

 Leu Ser Phe Ser Asn Trp Pro Pro Ser Leu Val Pro His Phe Leu
                 125                 130                 135

 Lys Ser Pro Val His Cys His Gln Ile Lys Leu Ser Pro Ala Arg
                 140                 145                 150

 Ser Pro Leu Ser Glu Lys Pro Pro Leu Thr Trp Lys His His Cys
                 155                 160                 165

 Leu Ala His Ile Leu Thr Tyr Pro Pro Ser Arg Leu Asp Pro His
                 170                 175                 180

 Thr Ser Phe Gln Pro Pro Leu Pro Leu His Ser Leu Leu Ser Pro
                 185                 190                 195

 Pro Pro Pro His Pro Leu Val Ser Pro Pro Leu
                 200                 205

<210> 3145
<211> 1155
<212> DNA
<213> Homo sapien

<400> 3145
 cccgagacca cgtggcctcc gagcagctca gggcgccctt gaaagttctt 50

 ggatctgcgg gttatggccg gtcccttgca gggcggtggg gcccgggccc 100

 tggacctact ccggggcctg ccgcgtgtga gcctggccaa cttaaagccg 150

 aatcccggct ccaagaaacc ggagagaaga ccaagaggtc ggagaagagg 200

 tagaaaatgt ggcagaggcc ataaaggaga aaggcaaaga ggaacccggc 250

 cccgcttggg ctttgaggga ggccagactc cattttacat ccgaatccca 300

 aaatacgggt ttaacgaagg acatagtttc agacgccagt ataagccttt 350

 gagtctcaat agactgcagt atcttattga tttgggtcgt gttgatccta 400

 gtcaacctat tgacttaacc cagcttgtca atgggagagg tgtgaccatc 450

 cagccactta aaagggatta tggtgtccag ctggttgagg agggtgctga 500

 cacctttacg gcaaaagtta atattgaagt acagttggct tcagaactag 550

 ctattgctgc cattgaaaaa aatggtggtg ttgttactac agccttctat 600

 gatccaagaa gtctggacat tgtatgcaaa cctgttccat tctttcttcg 650

 tggacaaccc attccaaaaa gaatgcttcc accagaagaa ctggtaccat 700

 attacactga tgcaaagaac cgtgggtacc tggcggatcc tgccaaattt 750

 cctgaagcac gacttgaact cgccaggaag tatggttata tcttacctga 800

 tatcactaaa gatgaactct tcaaaatgct ctgtactagg aaggatccaa 850

 ggcagatttt ctttggtctt gctccaggat gggtggtgaa tatggccgat 900

 aagaaaatcc taaaacctac agatgaaaat ctccttaagt attatacctc 950

 atgaattccc gtccaaggaa gcagagttgt taaagagtac tggaataggg 1000

 gctgaaggat ctatattccc ttattgcatt ttccttatgt ataattttcc 1050

 agatggtgat gttacttttc agtgtactca tatgtctcat tttcatctaa 1100

 aattaaatgg caggaaacaa ggactgcata gagaaaaaaa aaaaaaaaaa 1150

 aaaaa 1155

<210> 3146
<211> 296
<212> PRT
<213> Homo sapien

<400> 3146
 Met Ala Gly Pro Leu Gln Gly Gly Gly Ala Arg Ala Leu Asp Leu
   1               5                  10                  15

 Leu Arg Gly Leu Pro Arg Val Ser Leu Ala Asn Leu Lys Pro Asn
                  20                  25                  30

 Pro Gly Ser Lys Lys Pro Glu Arg Arg Pro Arg Gly Arg Arg Arg
                  35                  40                  45

 Gly Arg Lys Cys Gly Arg Gly His Lys Gly Glu Arg Gln Arg Gly
                  50                  55                  60

 Thr Arg Pro Arg Leu Gly Phe Glu Gly Gly Gln Thr Pro Phe Tyr
                  65                  70                  75

 Ile Arg Ile Pro Lys Tyr Gly Phe Asn Glu Gly His Ser Phe Arg
                  80                  85                  90

 Arg Gln Tyr Lys Pro Leu Ser Leu Asn Arg Leu Gln Tyr Leu Ile
                  95                 100                 105

 Asp Leu Gly Arg Val Asp Pro Ser Gln Pro Ile Asp Leu Thr Gln
                 110                 115                 120

 Leu Val Asn Gly Arg Gly Val Thr Ile Gln Pro Leu Lys Arg Asp
                 125                 130                 135

 Tyr Gly Val Gln Leu Val Glu Glu Gly Ala Asp Thr Phe Thr Ala
                 140                 145                 150

 Lys Val Asn Ile Glu Val Gln Leu Ala Ser Glu Leu Ala Ile Ala
                 155                 160                 165

 Ala Ile Glu Lys Asn Gly Gly Val Val Thr Thr Ala Phe Tyr Asp
                 170                 175                 180

 Pro Arg Ser Leu Asp Ile Val Cys Lys Pro Val Pro Phe Phe Leu
                 185                 190                 195

 Arg Gly Gln Pro Ile Pro Lys Arg Met Leu Pro Pro Glu Glu Leu
                 200                 205                 210

 Val Pro Tyr Tyr Thr Asp Ala Lys Asn Arg Gly Tyr Leu Ala Asp
                 215                 220                 225

 Pro Ala Lys Phe Pro Glu Ala Arg Leu Glu Leu Ala Arg Lys Tyr
                 230                 235                 240

 Gly Tyr Ile Leu Pro Asp Ile Thr Lys Asp Glu Leu Phe Lys Met
                 245                 250                 255

 Leu Cys Thr Arg Lys Asp Pro Arg Gln Ile Phe Phe Gly Leu Ala
                 260                 265                 270

 Pro Gly Trp Val Val Asn Met Ala Asp Lys Lys Ile Leu Lys Pro
                 275                 280                 285

 Thr Asp Glu Asn Leu Leu Lys Tyr Tyr Thr Ser
                 290                 295

<210> 3147
<211> 4020
<212> DNA
<213> Homo sapien

<400> 3147
 gtcaattgcc ctttagtccc aggactaacc ggaagcttct gcaacaggag 50

 gacattgaaa ataagatgga acccatccac ataaggattt gcctcaaagg 100

 gcactgcaaa aattgaacag aggaatccca aggaagctgc ctgaatttgc 150

 ctgtatactc tcgttctgcg acttataaag gaccagacaa atcaaattag 200

 tggttttggt ttccgccagc tgtggatgcc tttgacatta tgaccgcaga 250

 ggattccacc gcagccatga gcagtgactc ggccgccggg tcctcggcca 300

 aggtgcccga gggcgtggcg ggcgcgccca acgaggcagc actgctggcg 350

 ctgatggagc gcacgggcta cagcatggtg caagagaacg ggcagcgcaa 400

 gtacggcggc ccaccgcccg gctgggaggg cccgcacccg cagcgtggct 450

 gcgaggtctt cgtgggcaag atcccgcgcg acgtgtacga ggacgagctg 500

 gtgcccgtgt tcgaggccgt gggccgcacc tacgagctgc gcctcatgat 550

 ggactttgac ggcaagaacc gcggctacgc cttcgtcatg tactgccaca 600

 agcacgaggc caagcgcgca gtgcgtgagc tcaacaacta cgagatccgc 650

 ccgggccgcc tgctcggcgt gtgctgcagc gtggacaact gccgcctctt 700

 catcggcggg atccccaaga tgaagaagcg cgaggaaatc ctggaggaga 750

 ttgccaaggt caccgagggc gtgctggacg tgatcgtcta cgccagcgcg 800

 gccgacaaga tgaagaaccg cggcttcgcc ttcgtggagt acgagagcca 850

 ccgcgcggct gccatggctc gccgcaagct catgcctggc cgcatccagc 900

 tgtggggcca ccagatcgcc gtggactggg ccgagcctga gatcgacgtg 950

 gacgaggacg tgatggagac cgtgaagatc ctctacgtgc gcaacctcat 1000

 gatcgagacc accgaggaca ccatcaagaa gagcttcggc cagttcaacc 1050

 ccggctgcgt ggagcgcgtc aagaagatcc gcgactacgc cttcgtgcac 1100

 ttcaccagcc gcgaggatgc cgtgcatgcc atgaacaacc tcaacggcac 1150

 tgagctggag ggctcgtgcc tggaggtcac gctggccaag cccgtggaca 1200

 aggagcagta ctcgcgctac cagaaggcag ccaggggcgg cggcgcggct 1250

 gaggcagcgc agcagcccag ctacgtgtac tcctgcgacc cctacacact 1300

 ggcctactac ggctacccct acaacgcgct cattgggccc aacagggact 1350

 actttgtgaa agtagccatc cctgccattg gggctcagta ttccatgttt 1400

 ccagcagctc cagcccctaa aatgattgaa gatggcaaaa tccacacagt 1450

 ggagcacatg atcagcccca ttgctgtgca gccagaccca gccagtgctg 1500

 ctgccgccgc agccgcggcc gcagccgccg cagccgctgt cattcccact 1550

 gtgtcgacgc caccaccttt ccagggccgc ccaataactc cagtatacac 1600

 ggtggctcca aacgttcaga gaattcctac tgccgggatc tacggggcca 1650

 gttacgtgcc atttgctgct ccagctacag ccacgatcgc cacactacag 1700

 aagaacgcgg cagccgcggc cgccgtgtat ggaggatacg caggctacat 1750

 acctcaggcc ttccctgctg ctgccattca ggtccccatc cccgacgtct 1800

 accagacata ctgaggctgg tgaccagcac gaagacagac cacacaaaca 1850

 ccactgaagg aacgcttgac tatttatgaa gaaggaacat gttggattca 1900

 cacatgcaac ctgaaagtga agaatgttag cagatttatt tctgaattat 1950

 tttatataca tgaagttttc actagttttt taagactatt ttcaacttag 2000

 catgcctacg ttcatacatt tccaaaagac ttgcaatggt tcgtgccttc 2050

 attccatctt ttaaaaattt gtatgctgta ctacatttgt atagaggttt 2100

 ttgttgttgt ttttttaagg atatattttc agtatgaagg ttattttctt 2150

 aacttctgca ctccagagat ttctattttg tagtaccttc aataatatat 2200

 caactatata ttaaaaaagc acacttgagg agctagggaa ctattttgaa 2250

 aaatatatac aatatttaaa gatacaaaca gtagtgctta aaaatactac 2300

 ataaagcatt attttaaagg ttatactgga aagtgcaatt ttaaaatgag 2350

 taaaacctct gtatttctgc tggcattaag ggttgatggt gttaccatgt 2400

 atcatcatgg cggtactatt ttttaaaaga aattaaacac tggatctctc 2450

 cttaagccaa cattgaaaag acttgccgca cttctgagtc caaacactgg 2500

 aaagctctcc ttgccaccgt tagccggggc tcattctcca tgtgccttag 2550

 ccttaaacat gcccccactc ccacatctct caccctgtcc cctcctcccc 2600

 agattcccaa tcccaccgca atgtttggca agcctaggac tgataagtag 2650

 ctctgataga ggagctggtg gcttttatac ttcttcctgg gtttttgttg 2700

 gggtttgttg tttcgttgtt ttttgttttt tttttgtttg gttggggaag 2750

 tattgtcttc tacgtgtgct attttcagta gcagagtaag cacaaggttt 2800

 taatcgagtt gcataagaca cctttgcata gctatttaat tgcccaatgt 2850

 aaaactttaa tgccatttct aatgctttta ttcatttttg aagtatgagt 2900

 ttgtagggac aaagaatgta tgttatcgta gacaagaccc ccagagactc 2950

 ttttcagcag aaagttatgc ttctagttgc cttaccatgt ttcttgcaaa 3000

 actgtccatg gtcctcaagg gtgttggaaa cattatgttt attaaatggg 3050

 cctctcttcc tttgctgtgc acttgatggg tgaactggat tggggtgtgc 3100

 acatccagga ggaggaggag agacctgtag aagtttaaag atagtttgta 3150

 aatatcttct aatgcttgtt tttagtcctt ttatgttgga gaagttcatg 3200

 gtatgtagtt taatgcaaaa tgaaaccatt ttatttcaat gttattaaaa 3250

 aggtttgttt tattaggaag ttaatgtatt gttgcagtgt tttgtgcctg 3300

 tttaaaggct tttgtttagc agagtgaatg taaaatacag taaaatgtta 3350

 agattgtcat ctacttttta aaaaaaaata tcaacttgga attgtttttt 3400

 aaaggctcaa tcaaggaagt gaggtgtgca ataaggtagc aagtaaaacg 3450

 cagttgcgtt tttatgtcat gttagagatc catacaattt tccactcacg 3500

 ggatttttgt tgatggctga attcttgtgg attcataaga ggatcatgcc 3550

 cttagcaagt acttttgttt tgttttaaat taagagattc ccaaatgcct 3600

 ttttccccct catcttgaaa tgagatgagt ttttatgtgt aagcaatatt 3650

 tatttaacta ttctataaaa ttattgagtg cctactgagg cctttaagca 3700

 ccgctaacat tcctttccat cattcttttg aatgacataa aataattgtg 3750

 caatgttcct gatgatgtac cccacagctg cattcaaact caaatctgtg 3800

 ggaatgagtg actcgaccaa atgtaattcg gatcagatcc tcatcccctg 3850

 actgtgtgaa aaaagtactc tccttctagt gaaggattgt cacagagttt 3900

 cactggatga aactatgacc cagtattctt actgtatttt acatgtgcct 3950

 gtaaattatt ttgccgaaat aagaagaaga agaggaagaa agaacagtag 4000

 aaaaaaaaaa taaaaaaaaa 4020

<210> 3148
<211> 524
<212> PRT
<213> Homo sapien

<400> 3148
 Met Thr Ala Glu Asp Ser Thr Ala Ala Met Ser Ser Asp Ser Ala
   1               5                  10                  15

 Ala Gly Ser Ser Ala Lys Val Pro Glu Gly Val Ala Gly Ala Pro
                  20                  25                  30

 Asn Glu Ala Ala Leu Leu Ala Leu Met Glu Arg Thr Gly Tyr Ser
                  35                  40                  45

 Met Val Gln Glu Asn Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro
                  50                  55                  60

 Gly Trp Glu Gly Pro His Pro Gln Arg Gly Cys Glu Val Phe Val
                  65                  70                  75

 Gly Lys Ile Pro Arg Asp Val Tyr Glu Asp Glu Leu Val Pro Val
                  80                  85                  90

 Phe Glu Ala Val Gly Arg Thr Tyr Glu Leu Arg Leu Met Met Asp
                  95                 100                 105

 Phe Asp Gly Lys Asn Arg Gly Tyr Ala Phe Val Met Tyr Cys His
                 110                 115                 120

 Lys His Glu Ala Lys Arg Ala Val Arg Glu Leu Asn Asn Tyr Glu
                 125                 130                 135

 Ile Arg Pro Gly Arg Leu Leu Gly Val Cys Cys Ser Val Asp Asn
                 140                 145                 150

 Cys Arg Leu Phe Ile Gly Gly Ile Pro Lys Met Lys Lys Arg Glu
                 155                 160                 165

 Glu Ile Leu Glu Glu Ile Ala Lys Val Thr Glu Gly Val Leu Asp
                 170                 175                 180

 Val Ile Val Tyr Ala Ser Ala Ala Asp Lys Met Lys Asn Arg Gly
                 185                 190                 195

 Phe Ala Phe Val Glu Tyr Glu Ser His Arg Ala Ala Ala Met Ala
                 200                 205                 210

 Arg Arg Lys Leu Met Pro Gly Arg Ile Gln Leu Trp Gly His Gln
                 215                 220                 225

 Ile Ala Val Asp Trp Ala Glu Pro Glu Ile Asp Val Asp Glu Asp
                 230                 235                 240

 Val Met Glu Thr Val Lys Ile Leu Tyr Val Arg Asn Leu Met Ile
                 245                 250                 255

 Glu Thr Thr Glu Asp Thr Ile Lys Lys Ser Phe Gly Gln Phe Asn
                 260                 265                 270

 Pro Gly Cys Val Glu Arg Val Lys Lys Ile Arg Asp Tyr Ala Phe
                 275                 280                 285

 Val His Phe Thr Ser Arg Glu Asp Ala Val His Ala Met Asn Asn
                 290                 295                 300

 Leu Asn Gly Thr Glu Leu Glu Gly Ser Cys Leu Glu Val Thr Leu
                 305                 310                 315

 Ala Lys Pro Val Asp Lys Glu Gln Tyr Ser Arg Tyr Gln Lys Ala
                 320                 325                 330

 Ala Arg Gly Gly Gly Ala Ala Glu Ala Ala Gln Gln Pro Ser Tyr
                 335                 340                 345

 Val Tyr Ser Cys Asp Pro Tyr Thr Leu Ala Tyr Tyr Gly Tyr Pro
                 350                 355                 360

 Tyr Asn Ala Leu Ile Gly Pro Asn Arg Asp Tyr Phe Val Lys Val
                 365                 370                 375

 Ala Ile Pro Ala Ile Gly Ala Gln Tyr Ser Met Phe Pro Ala Ala
                 380                 385                 390

 Pro Ala Pro Lys Met Ile Glu Asp Gly Lys Ile His Thr Val Glu
                 395                 400                 405

 His Met Ile Ser Pro Ile Ala Val Gln Pro Asp Pro Ala Ser Ala
                 410                 415                 420

 Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Val Ile
                 425                 430                 435

 Pro Thr Val Ser Thr Pro Pro Pro Phe Gln Gly Arg Pro Ile Thr
                 440                 445                 450

 Pro Val Tyr Thr Val Ala Pro Asn Val Gln Arg Ile Pro Thr Ala
                 455                 460                 465

 Gly Ile Tyr Gly Ala Ser Tyr Val Pro Phe Ala Ala Pro Ala Thr
                 470                 475                 480

 Ala Thr Ile Ala Thr Leu Gln Lys Asn Ala Ala Ala Ala Ala Ala
                 485                 490                 495

 Val Tyr Gly Gly Tyr Ala Gly Tyr Ile Pro Gln Ala Phe Pro Ala
                 500                 505                 510

 Ala Ala Ile Gln Val Pro Ile Pro Asp Val Tyr Gln Thr Tyr
                 515                 520

<210> 3149
<211> 2268
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 13
<223> Unknown base

<400> 3149
 gggatttgaa ccncgctgac gaagtttggt gatccatctt ccgagtatcg 50

 ccgggatttc gaatcgcgat gatcatcccc tctctagagg agctggactc 100

 cctcaagtac agtgacctgc agaacttagc caagagtctg ggtctccggg 150

 ccaacctgag ggcaaccaag ttgttaaaag ccttgaaagg ctacattaaa 200

 catgaggcaa gaaaaggaaa tgagaatcag gatgaaagtc aaacttctgc 250

 atcctcttgt gatgagactg agatacagat cagcaaccag gaagaagctg 300

 agagacagcc acttggccat gtcaccaaaa caaggagaag gtgcaagact 350

 gtccgtgtgg accctgactc acagcagaat cattcagaga taaaaataag 400

 taatcccact gaattccaga atcatgaaaa gcaggaaagc caggatctca 450

 gagctactgc aaaagttcct tctccaccag acgagcacca agaagctgag 500

 aatgctgttt cctcaggtaa cagagattca aaggtacctt cagaaggaaa 550

 gaaatctctc tacacagatg agtcatccaa acctggaaaa aataaaagaa 600

 ctgcaatcac tactccaaac tttaagaagc ttcatgaagc tcattttaag 650

 gaaatggagt ccattgatca atatattgag agaaaaagaa acattttgaa 700

 gaacacaatt ccatgaatga actgaagcag cagcccatca ataagggagg 750

 ggtcaggact ccagtacctc caagaggaag actctctgtg gcttctactc 800

 ccatcagcca acgacgctcg caaggccggt cttgtggccc tgcaagtcag 850

 agtaccttgg gtctgaaggg gtcactcaag cgctctgcta tctctgcagc 900

 taaaacgggt gtcaggtttt cagctgctac taaagataat gagcataagc 950

 gttcactgac caagactcca gccagaaagt ctgcacatgt gaccgtgtct 1000

 gggggcaccc caaaaggcga ggctgtgctt gggacacaca aattaaagac 1050

 catcacgggg aattctgctg ctgttattac cccattcaag ttgacaactg 1100

 aggcaacgca gactccagtc tccaataaga aaccagtgtt tgatcttaaa 1150

 gcaagtttgt ctcgtcccct caactatgaa ccacacaaag gaaagctaaa 1200

 accatggggg caatctaaag aaaataatta tctaaatcaa catgtcaaca 1250

 gaattaactt ctacaagaaa acttacaaac aaccccatct ccagacaaag 1300

 gaagagcaac ggaagaaacg cgagcaagaa cgaaaggaga agaaagcaaa 1350

 ggttttggga atgcgaaggg gcctcatttt ggctgaagat taataatttt 1400

 ttaatatctt gtaaatattc ctgtattctc aacttttttc cttttgtaaa 1450

 tttttttttt tttgctgtca tccccacttt agtcacgaga tctttttctg 1500

 ctaactgttc atagtctgtg tagtgtccat gggttcttca tgtgctatga 1550

 tctctgaaaa gacgttatca ccttaaagct caaattcttt gggatggttt 1600

 ttacttaagt ccattaacaa ttcaggtttc taacgagacc catcctaaaa 1650

 ttctgtttct agatttttaa tgtcaagttc ccaagttccc cctgctggtt 1700

 ctaatattaa cagaactgca gtcttctgct agccaatagc atttacctga 1750

 tggcagctag ttatgcaagc ttcaggagaa tttgaacaat aacaagaata 1800

 gggtaagctg ggatagaaag gccacctctt cactctctat agaatatagt 1850

 aacctttatg aaacggggcc atatagtttg gttatgacat caatatttta 1900

 cctaggtgaa attgtttagg cttatgtacc ttcgttcaaa tatcctcatg 1950

 taattgccat ctgtcactca ctatattcac aaaaataaaa ctctacaact 2000

 cattctaaca ttgcttactt aaaagctaca tagccctatc gaaatgcgag 2050

 gattaatgct ttaatgcttt tagagacagg gtctcactgt gttgcccagg 2100

 ctggtctcaa actccaccaa atgtacttct tattcatttt atggaaaaga 2150

 ctaggctttg cttagtatca tgtccatgtt tccttcacct cagtggagct 2200

 tctgagtttt atactgctca agatcgtcat aaataaaatt ttttctcatt 2250

 gtcaaaaaaa aaaaaaaa 2268

<210> 3150
<211> 226
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 13
<223> Unknown amino acid

<400> 3150
 Met Asn Glu Leu Lys Gln Gln Pro Ile Asn Lys Gly Gly Val Arg
   1               5                  10                  15

 Thr Pro Val Pro Pro Arg Gly Arg Leu Ser Val Ala Ser Thr Pro
                  20                  25                  30

 Ile Ser Gln Arg Arg Ser Gln Gly Arg Ser Cys Gly Pro Ala Ser
                  35                  40                  45

 Gln Ser Thr Leu Gly Leu Lys Gly Ser Leu Lys Arg Ser Ala Ile
                  50                  55                  60

 Ser Ala Ala Lys Thr Gly Val Arg Phe Ser Ala Ala Thr Lys Asp
                  65                  70                  75

 Asn Glu His Lys Arg Ser Leu Thr Lys Thr Pro Ala Arg Lys Ser
                  80                  85                  90

 Ala His Val Thr Val Ser Gly Gly Thr Pro Lys Gly Glu Ala Val
                  95                 100                 105

 Leu Gly Thr His Lys Leu Lys Thr Ile Thr Gly Asn Ser Ala Ala
                 110                 115                 120

 Val Ile Thr Pro Phe Lys Leu Thr Thr Glu Ala Thr Gln Thr Pro
                 125                 130                 135

 Val Ser Asn Lys Lys Pro Val Phe Asp Leu Lys Ala Ser Leu Ser
                 140                 145                 150

 Arg Pro Leu Asn Tyr Glu Pro His Lys Gly Lys Leu Lys Pro Trp
                 155                 160                 165

 Gly Gln Ser Lys Glu Asn Asn Tyr Leu Asn Gln His Val Asn Arg
                 170                 175                 180

 Ile Asn Phe Tyr Lys Lys Thr Tyr Lys Gln Pro His Leu Gln Thr
                 185                 190                 195

 Lys Glu Glu Gln Arg Lys Lys Arg Glu Gln Glu Arg Lys Glu Lys
                 200                 205                 210

 Lys Ala Lys Val Leu Gly Met Arg Arg Gly Leu Ile Leu Ala Glu
                 215                 220                 225

 Asp


<210> 3151
<211> 1143
<212> DNA
<213> Homo sapien

<400> 3151
 ggagctctgg aggcggggct tcgagcgtgg ctcgtgggtt ttccgtgaag 50

 tcgcggtgca gcggtgggcg gcatgtctgt ggccggtggg gagattcgtg 100

 gggacacggg gggagaggac actgctgctc ccggccggtt cagcttcagc 150

 ccggagccca cgctcgagga catccgccgc ctccatgctg agtttgctgc 200

 ggaacgagac tgggaacagt tccatcagcc tcggaatctc ctcctggcct 250

 tggttgggga agtgggggag ctggcagaac tctttcagtg gaaaaccgat 300

 ggggaacctg gcccccaagg ctggtccccc agggaacggg cagcccttca 350

 agaggagctt agtgacgtcc tcatctacct ggtggcatta gcagcccgct 400

 gccgtgtgga tctgccgcta gcagtgctct ccaaaatgga catcaaccgg 450

 cgacgctacc cagcccatct ggcccgcagc tcttcccgca agtatacaga 500

 attgccccat ggggccatct ctgaagacca ggctgtgggg cctgcggaca 550

 ttccctgtga ctccacaggc cagacctcaa cctagaaaga tggccacagg 600

 acttgcaact cagggtggtg tctgaagagc agagagtggc ctggccctgg 650

 agcctttttc tagtcttttc agaatagatc atgggcctga ggcctccact 700

 tcttgaggtc tgaggcccag cagcctctag aaggtagcct cctggtgttt 750

 gttctcccag taaaatggtt ttgggcgata acttctagat tattcctgga 800

 tggccaggga ggctctctgt ctcagcaggt gatgacgggg gtaccagggg 850

 tgcctctgag acccattctc gtgtttccct gttgtacctt ttgcctgcag 900

 ggcagagaga tctggtttct agcaaattcc cagtaggatg tcatgtaagt 950

 tccttccccc tcttagagat tgaaggctgt aagagtccag atggtggagc 1000

 caggctgtct gggttcaaat gccatctttg acacttgcaa gctaaatgac 1050

 attactcaaa ttaatcgttc tgcacttcag cttccttgtc tatcaaataa 1100

 aaagaatagt acctgcccaa aaaaaaaaaa aaaaaaaaaa aaa 1143

<210> 3152
<211> 170
<212> PRT
<213> Homo sapien

<400> 3152
 Met Ser Val Ala Gly Gly Glu Ile Arg Gly Asp Thr Gly Gly Glu
   1               5                  10                  15

 Asp Thr Ala Ala Pro Gly Arg Phe Ser Phe Ser Pro Glu Pro Thr
                  20                  25                  30

 Leu Glu Asp Ile Arg Arg Leu His Ala Glu Phe Ala Ala Glu Arg
                  35                  40                  45

 Asp Trp Glu Gln Phe His Gln Pro Arg Asn Leu Leu Leu Ala Leu
                  50                  55                  60

 Val Gly Glu Val Gly Glu Leu Ala Glu Leu Phe Gln Trp Lys Thr
                  65                  70                  75

 Asp Gly Glu Pro Gly Pro Gln Gly Trp Ser Pro Arg Glu Arg Ala
                  80                  85                  90

 Ala Leu Gln Glu Glu Leu Ser Asp Val Leu Ile Tyr Leu Val Ala
                  95                 100                 105

 Leu Ala Ala Arg Cys Arg Val Asp Leu Pro Leu Ala Val Leu Ser
                 110                 115                 120

 Lys Met Asp Ile Asn Arg Arg Arg Tyr Pro Ala His Leu Ala Arg
                 125                 130                 135

 Ser Ser Ser Arg Lys Tyr Thr Glu Leu Pro His Gly Ala Ile Ser
                 140                 145                 150

 Glu Asp Gln Ala Val Gly Pro Ala Asp Ile Pro Cys Asp Ser Thr
                 155                 160                 165

 Gly Gln Thr Ser Thr
                 170

<210> 3153
<211> 1282
<212> DNA
<213> Homo sapien

<400> 3153
 gtgctcggcg ttgagctcct gcagccgccg ccgctgcagt ggtcgtccct 50

 gccctccccg gccccggggt gcaccccgca aggctcccgc tggtgtccct 100

 ggagcatggg aggctgctga gcgtgagtgg cggtgtctgg caggagctgc 150

 gtggcaggga gggcgtccat ggctgcagcc aacaagggca acaagcccag 200

 agtccggggt atccgctttg cggcaggcca cgatgcagaa ggatcccaca 250

 gccacgtcca ctttgatgag aagctgcatg actcggtggt catggtcacc 300

 caggagagtg acagcagctt tctggtcaag gttggcttcc tgaagatcct 350

 gcacaggtat gagattacct tcactctgcc cccagtgcac aggctgagca 400

 aggatgtccg cgaggcacct gtccccagcc tgcacctcaa gctcctcagc 450

 gtggtgcccg tccctgaagg ttatagtgtc aagtgtgagt actcggcgca 500

 caaagagggc gtcctcaaag aggagatact gctagcctgc gaaggtggca 550

 ctggcacctg tgtgcgcgtg acggtgcagg cccgcgtcat ggaccggcac 600

 cacggcacgc ccatgctgct ggatggtgtc aagtgtgtgg gcgccgagct 650

 ggaatacgac tcagagcaca gcgactggca cggctttgac tgaggcccga 700

 ggccccgcct gccccgggcc cctcagcctt aaaccccgcc ttgtcccccc 750

 gacatgctgc gtgatggtgt ggcttcctcg cccctctctg gggtgggtgt 800

 gggggtggag tggccttgcc cacgcctctc acctctgcct tcatttgtgc 850

 tgccaccctg cccctccctc gtcctcctct cccacttcct cctctctgtg 900

 tgcctcagtc tcctgccgga agaaatgggt tgatcccgaa aggaggctgt 950

 ctgaggaagg gagagggagg gcctggggtg ggtcccccac tccccacccc 1000

 aagccacagg gactcccacc agggtctggg agaggacgga gctggctctg 1050

 tggcgtcgtg gccccattac tgctgccttg cttcagccac ctctcctgcc 1100

 cctccctagt ccccactgct gtccaccatg agtaggaggg aggtgcagtc 1150

 cccagccccc acccctcagg tctgtgttac ttggttttta agcgactggt 1200

 tgggatagaa ccctaaagaa ataaacttcc agtggataaa aaaaaaaaaa 1250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1282

<210> 3154
<211> 174
<212> PRT
<213> Homo sapien

<400> 3154
 Met Ala Ala Ala Asn Lys Gly Asn Lys Pro Arg Val Arg Gly Ile
   1               5                  10                  15

 Arg Phe Ala Ala Gly His Asp Ala Glu Gly Ser His Ser His Val
                  20                  25                  30

 His Phe Asp Glu Lys Leu His Asp Ser Val Val Met Val Thr Gln
                  35                  40                  45

 Glu Ser Asp Ser Ser Phe Leu Val Lys Val Gly Phe Leu Lys Ile
                  50                  55                  60

 Leu His Arg Tyr Glu Ile Thr Phe Thr Leu Pro Pro Val His Arg
                  65                  70                  75

 Leu Ser Lys Asp Val Arg Glu Ala Pro Val Pro Ser Leu His Leu
                  80                  85                  90

 Lys Leu Leu Ser Val Val Pro Val Pro Glu Gly Tyr Ser Val Lys
                  95                 100                 105

 Cys Glu Tyr Ser Ala His Lys Glu Gly Val Leu Lys Glu Glu Ile
                 110                 115                 120

 Leu Leu Ala Cys Glu Gly Gly Thr Gly Thr Cys Val Arg Val Thr
                 125                 130                 135

 Val Gln Ala Arg Val Met Asp Arg His His Gly Thr Pro Met Leu
                 140                 145                 150

 Leu Asp Gly Val Lys Cys Val Gly Ala Glu Leu Glu Tyr Asp Ser
                 155                 160                 165

 Glu His Ser Asp Trp His Gly Phe Asp
                 170

<210> 3155
<211> 1434
<212> DNA
<213> Homo sapien

<400> 3155
 ggggaagtcg aggcgggagt gactctgctt ccgtttctgg ttttgctcta 50

 gtgtttgggt ttcttcgcgg ctgctcaaga tgaaccgact cttcgggaaa 100

 gcgaaaccca aggctccgcc gcccagcctg actggctgca ttggcacggt 150

 ggacagtaga gcagaatcca ttgacaagaa gatttctcga ttggatgctg 200

 agctagtgaa gtataaggat cagatcaaga agatgagaga gggtcctgca 250

 aagaatatgg tcaagcagaa agccttgcga gttttaaagc aaaagaggat 300

 gtatgagcag cagcgggaca atcttgccca acagtcattc aacatggaac 350

 aagccaatta taccatccag tctttgaagg acaccaagac cacggttgat 400

 gctatgaaac tgggagtaaa ggaaatgaag aaggcataca agcaagtgaa 450

 gatcgaccag attgaggatt tacaagacca gctagaggat atgatggaag 500

 atgcaaatga aatccaagaa gcactgagtc gcagttatgg caccccagaa 550

 ctggatgaag atgatttaga agcagagttg gatgcactag gtgatgagct 600

 tctggctgat gaagacagtt cttatttgga tgaggcagca tctgcacctg 650

 caattccaga aggtgttccc actgatacaa aaaacaagga tggagttctg 700

 gtggatgaat ttggattgcc acagatccct gcttcataga tttgcatcat 750

 tcaagcatat cttgtaaaac aaacacatat tatgggacta ggaaatattt 800

 atctttccaa atttgccata acagatttag gtttctttcc tttctttgaa 850

 ggaaagttta attacattgc tcttttattt tttccattaa gagactcatt 900

 gcttgggaaa tgctttcttc gtactaaaat ttgattcctt tttttcttat 950

 gaaaaacgaa ctcagtttaa aagtattttt agctcgtatg acttgttttc 1000

 attcattaat aataatttga aataaaacta aggaaatgga atcttaaaag 1050

 tctatgacag tgtaactcta cagtctcaaa atgacctgat aaattgataa 1100

 gacaaagatg agattattgg ggctgttcat attatgattc agaatcattt 1150

 tctattgtgg tattataggt tggttaaagt gatggccttt ttgatgggtt 1200

 ttgttgtgtc ttgtgaacaa gtcgttactg tgtccattat tggaatggaa 1250

 ttatcactac tgtatcatga gtgggtattt tgattctatg gttccctcag 1300

 tattacatct tgacttgtaa tcaattatga atatttcttg atatttaatg 1350

 tataggacat ttatttatac tcaataaata tttttcaaaa ggaaaaaaaa 1400

 aaaaatcaaa aaaaaaaaaa aaaaaaaaaa aaaa 1434

<210> 3156
<211> 219
<212> PRT
<213> Homo sapien

<400> 3156
 Met Asn Arg Leu Phe Gly Lys Ala Lys Pro Lys Ala Pro Pro Pro
   1               5                  10                  15

 Ser Leu Thr Gly Cys Ile Gly Thr Val Asp Ser Arg Ala Glu Ser
                  20                  25                  30

 Ile Asp Lys Lys Ile Ser Arg Leu Asp Ala Glu Leu Val Lys Tyr
                  35                  40                  45

 Lys Asp Gln Ile Lys Lys Met Arg Glu Gly Pro Ala Lys Asn Met
                  50                  55                  60

 Val Lys Gln Lys Ala Leu Arg Val Leu Lys Gln Lys Arg Met Tyr
                  65                  70                  75

 Glu Gln Gln Arg Asp Asn Leu Ala Gln Gln Ser Phe Asn Met Glu
                  80                  85                  90

 Gln Ala Asn Tyr Thr Ile Gln Ser Leu Lys Asp Thr Lys Thr Thr
                  95                 100                 105

 Val Asp Ala Met Lys Leu Gly Val Lys Glu Met Lys Lys Ala Tyr
                 110                 115                 120

 Lys Gln Val Lys Ile Asp Gln Ile Glu Asp Leu Gln Asp Gln Leu
                 125                 130                 135

 Glu Asp Met Met Glu Asp Ala Asn Glu Ile Gln Glu Ala Leu Ser
                 140                 145                 150

 Arg Ser Tyr Gly Thr Pro Glu Leu Asp Glu Asp Asp Leu Glu Ala
                 155                 160                 165

 Glu Leu Asp Ala Leu Gly Asp Glu Leu Leu Ala Asp Glu Asp Ser
                 170                 175                 180

 Ser Tyr Leu Asp Glu Ala Ala Ser Ala Pro Ala Ile Pro Glu Gly
                 185                 190                 195

 Val Pro Thr Asp Thr Lys Asn Lys Asp Gly Val Leu Val Asp Glu
                 200                 205                 210

 Phe Gly Leu Pro Gln Ile Pro Ala Ser
                 215

<210> 3157
<211> 1554
<212> DNA
<213> Homo sapien

<400> 3157
 gcgcgcctcg ccggcgcctc catcccggat ccttgctgca gcgtcagcgc 50

 cgccgcccgt gcctttcctc ttcctcctcc tcctccttgg catccgcctc 100

 ttcttcctcc tgcgtcctcc cccgctgcct ccgctgctcc cgacgcggag 150

 cccggagccc gcgccgagcc cctggcctcg cggtgccatg ctgccccggc 200

 ggcggcgctg aaggatggcg acgccgctgc ctccgccctc cccgcggcac 250

 ctgcggctgc tgcggctgct gctctccggc ctcgtcctcg gcgccgccct 300

 gcgtggagcc gccgccggcc acccggatgt agccgcctgt cccgggagcc 350

 tggactgtgc cctgaagagg cgggcaaggt gtcctcctgg tgcacatgcc 400

 tgtgggccct gccttcagcc cttccaggag gaccagcaag ggctctgtgt 450

 gcccaggatg cgccggcctc caggcggggg ccggccccag cccagactgg 500

 aagatgagat tgacttcctg gcccaggagc ttgcccggaa ggagtctgga 550

 cactcaactc cgcccctacc caaggaccga cagcggctcc cggagcctgc 600

 caccctgggc ttctcggcac gggggcaggg gctggagctg ggcctcccct 650

 ccactccagg aacccccacg cccacgcccc acacctccat gggctcccct 700

 gtgtcatccg acccggtgca catgtcgccc ctggagcccc ggggagggca 750

 aggcgacggc ctcgcccttg tgctgatcct ggcgttctgt gtggccggtg 800

 cagccgccct ctccgtagcc tccctctgct ggtgcaggct gcatcgtgag 850

 atccgcctga ctcagaaggc cgactacgcc actgcgaagg cccctggctc 900

 acctgcagct ccccggatct cgcctgggga ccaacggctg gcacagagcg 950

 cggagatgta ccactaccag caccaacggc aacagatgct gtgcctggag 1000

 cggcataaag agccacccaa ggagctggac acggcctcct cggatgagga 1050

 gaatgaggac ggagacttca cggtgtacga gtgcccgggc ctggccccga 1100

 ccggggaaat ggaggtgcgc aaccctctgt tcgaccacgc cgcactgtcc 1150

 gcgcccctgc cggcccccag ctcaccgcct gcactgccat gacctggagg 1200

 cagacagacg cccacctgct ccccgacctc gaggcccccg gggaggggca 1250

 gggcctggag cttcccacta aaaacatgtt ttgatgctgt gtgcttttgg 1300

 ctgggcctcg ggctccaggc cctgggaccc cttgccaggg agacccccga 1350

 acctttgtgc caggacacct cctggtcccc tgcacctctc ctgttcggtt 1400

 tagaccccca aactggaggg ggcatggaga accgtagagc gcaggaacgg 1450

 gtgggtaatt ctagagacaa aagccaatta aagtccattt cagaaaaaaa 1500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1550

 aaaa 1554

<210> 3158
<211> 325
<212> PRT
<213> Homo sapien

<400> 3158
 Met Ala Thr Pro Leu Pro Pro Pro Ser Pro Arg His Leu Arg Leu
   1               5                  10                  15

 Leu Arg Leu Leu Leu Ser Gly Leu Val Leu Gly Ala Ala Leu Arg
                  20                  25                  30

 Gly Ala Ala Ala Gly His Pro Asp Val Ala Ala Cys Pro Gly Ser
                  35                  40                  45

 Leu Asp Cys Ala Leu Lys Arg Arg Ala Arg Cys Pro Pro Gly Ala
                  50                  55                  60

 His Ala Cys Gly Pro Cys Leu Gln Pro Phe Gln Glu Asp Gln Gln
                  65                  70                  75

 Gly Leu Cys Val Pro Arg Met Arg Arg Pro Pro Gly Gly Gly Arg
                  80                  85                  90

 Pro Gln Pro Arg Leu Glu Asp Glu Ile Asp Phe Leu Ala Gln Glu
                  95                 100                 105

 Leu Ala Arg Lys Glu Ser Gly His Ser Thr Pro Pro Leu Pro Lys
                 110                 115                 120

 Asp Arg Gln Arg Leu Pro Glu Pro Ala Thr Leu Gly Phe Ser Ala
                 125                 130                 135

 Arg Gly Gln Gly Leu Glu Leu Gly Leu Pro Ser Thr Pro Gly Thr
                 140                 145                 150

 Pro Thr Pro Thr Pro His Thr Ser Met Gly Ser Pro Val Ser Ser
                 155                 160                 165

 Asp Pro Val His Met Ser Pro Leu Glu Pro Arg Gly Gly Gln Gly
                 170                 175                 180

 Asp Gly Leu Ala Leu Val Leu Ile Leu Ala Phe Cys Val Ala Gly
                 185                 190                 195

 Ala Ala Ala Leu Ser Val Ala Ser Leu Cys Trp Cys Arg Leu His
                 200                 205                 210

 Arg Glu Ile Arg Leu Thr Gln Lys Ala Asp Tyr Ala Thr Ala Lys
                 215                 220                 225

 Ala Pro Gly Ser Pro Ala Ala Pro Arg Ile Ser Pro Gly Asp Gln
                 230                 235                 240

 Arg Leu Ala Gln Ser Ala Glu Met Tyr His Tyr Gln His Gln Arg
                 245                 250                 255

 Gln Gln Met Leu Cys Leu Glu Arg His Lys Glu Pro Pro Lys Glu
                 260                 265                 270

 Leu Asp Thr Ala Ser Ser Asp Glu Glu Asn Glu Asp Gly Asp Phe
                 275                 280                 285

 Thr Val Tyr Glu Cys Pro Gly Leu Ala Pro Thr Gly Glu Met Glu
                 290                 295                 300

 Val Arg Asn Pro Leu Phe Asp His Ala Ala Leu Ser Ala Pro Leu
                 305                 310                 315

 Pro Ala Pro Ser Ser Pro Pro Ala Leu Pro
                 320                 325

<210> 3159
<211> 2584
<212> DNA
<213> Homo sapien

<400> 3159
 tggcggcggc ggcggcggtt gtcccggctg tgccggttgg tgtggcccgt 50

 cagcccgcgt accacagcgc ccgggccgcg tcgagcccag tacagccaag 100

 ccgctgcggc cgggtccggc gcgggcggcg cgcgcagacg gagggcggcg 150

 gccgcggcca gggcggcccg tgggaccgcg ggcccccggc gcagcgctgc 200

 ccggctcccg gccctgccgg cctcctccct tggcgccgcg gccatggcgg 250

 ccagcgcgaa gcggaagcag gaggagaagc acctgaagat gctgcgggac 300

 atgaccggcc tcccgcgcaa ccgaaagtgc ttcgactgcg accagcgcgg 350

 ccccacctac gttaacatga cggtcggctc cttcgtgtgt acctcctgct 400

 ccggcagcct gcgaggatta aatccaccac acagggtgaa atctatctcc 450

 atgacaacat tcacacaaca ggaaattgaa ttcttacaaa aacatggaaa 500

 tgaagtctgt aaacagattt ggctaggatt atttgatgat agatcttcag 550

 caattccaga cttcagggat ccacaaaaag tgaaagagtt tctacaagaa 600

 aagtatgaaa agaaaagatg gtatgtcccg ccagaacaag ccaaagtcgt 650

 ggcatcagtt catgcatcta tttcagggtc ctctgccagt agcacaagca 700

 gcacacctga ggtcaaacca ctgaaatctc ttttagggga ttctgcacca 750

 acactgcact taaataaggg cacacctagt cagtccccag ttgtaggtcg 800

 ttctcaaggg cagcagcagg agaagaagca atttgacctt ttaagtgatc 850

 tcggctcaga catctttgct gctccagctc ctcagtcaac agctacagcc 900

 aattttgcta actttgcaca tttcaacagt catgcagctc agaattctgc 950

 aaatgcagat tttgcaaact ttgatgcatt tggacagtct agtggttcga 1000

 gtaattttgg aggtttcccc acagcaagtc actctccttt tcagccccaa 1050

 actacaggtg gaagtgctgc atcagtaaat gctaattttg ctcattttga 1100

 taacttcccc aaatcctcca gtgctgattt tggaaccttc aatacttccc 1150

 agagtcatca aacagcatca gctgttagta aagtttcaac gaacaaagct 1200

 ggtttacaga ctgcagacaa atatgcagca cttgctaatt tagacaatat 1250

 cttcagtgcc gggcaaggtg gtgatcaggg aagtggcttt gggaccacag 1300

 gtaaagctcc tgttggttct gtggtttcag ttcccagtca gtcaagtgca 1350

 tcttcagaca agtatgcagc tctggcagaa ctagacagcg ttttcagttc 1400

 tgcagccacc tccagtaatg cgtatacttc cacaagtaat gctagcagca 1450

 atgtttttgg aacagtgcca gtggttgctt ctgcacagac acagcctgct 1500

 tcatcaagtg tgcctgctcc atttggacgt acgccttcca caaatccatt 1550

 tgttgctgct gctggtcctt ctgtggcatc ttctacaaac ccatttcaga 1600

 ccaatgccag aggagcaaca gcggcaacct ttggcactgc atccatgagc 1650

 atgcccacgg gattcggcac tcctgctccc tacagtcttc ccaccagctt 1700

 tagtggcagc tttcagcagc ctgcctttcc agcccaagca gctttccctc 1750

 aacagacagc tttttctcaa cagcccaatg gtgcaggttt tgcagcattt 1800

 ggacaaacaa agccagtagt aacccctttt ggtcaagttg cagctgctgg 1850

 agtatctagt aatcctttta tgactggtgc accaacagga caatttccaa 1900

 caggaagctc atcaaccaat cctttcttat agccttatat agacaattta 1950

 ctggaacgaa cttttatgtg gtcacattac atctctccac ctcttgcact 2000

 gttgtcttgt ttcactgatc ttagctttaa acacaagaga agtctttaaa 2050

 aagcctgcat tgtgtattaa acaccaggta atatgtgcaa aaccgagggc 2100

 tccagtaaca ccttctaacc tgtgaattgg cagaaaaggg tagcggtatc 2150

 atgtatatta aaattggcta atattaagtt attgcagata ccacattcat 2200

 tatgctgcag tactgtacat atttttctta gaaattagct atttgtgcat 2250

 atcagtattt gtaactttaa cacattgtta tgtgagaaat gttactgggg 2300

 aaatagatca gccactttta aggtgctgtc atatatcttg gaatgaatga 2350

 cctaaaatca ttttaaccat tgctactgga aagtaacaga gtcaaaattg 2400

 gaaggtttta ttcattcttg aatttttcct ttctaaagag ctcttctatt 2450

 tatacatgcc taaattcttt taaaatgtag agggatacct gtctgcataa 2500

 taaagctgat catgttttgc tacagtttgc aggtgaaaaa aaataaatat 2550

 tataaaataa aaaaaaaaaa aaagaaaaaa aaaa 2584

<210> 3160
<211> 562
<212> PRT
<213> Homo sapien

<400> 3160
 Met Ala Ala Ser Ala Lys Arg Lys Gln Glu Glu Lys His Leu Lys
   1               5                  10                  15

 Met Leu Arg Asp Met Thr Gly Leu Pro Arg Asn Arg Lys Cys Phe
                  20                  25                  30

 Asp Cys Asp Gln Arg Gly Pro Thr Tyr Val Asn Met Thr Val Gly
                  35                  40                  45

 Ser Phe Val Cys Thr Ser Cys Ser Gly Ser Leu Arg Gly Leu Asn
                  50                  55                  60

 Pro Pro His Arg Val Lys Ser Ile Ser Met Thr Thr Phe Thr Gln
                  65                  70                  75

 Gln Glu Ile Glu Phe Leu Gln Lys His Gly Asn Glu Val Cys Lys
                  80                  85                  90

 Gln Ile Trp Leu Gly Leu Phe Asp Asp Arg Ser Ser Ala Ile Pro
                  95                 100                 105

 Asp Phe Arg Asp Pro Gln Lys Val Lys Glu Phe Leu Gln Glu Lys
                 110                 115                 120

 Tyr Glu Lys Lys Arg Trp Tyr Val Pro Pro Glu Gln Ala Lys Val
                 125                 130                 135

 Val Ala Ser Val His Ala Ser Ile Ser Gly Ser Ser Ala Ser Ser
                 140                 145                 150

 Thr Ser Ser Thr Pro Glu Val Lys Pro Leu Lys Ser Leu Leu Gly
                 155                 160                 165

 Asp Ser Ala Pro Thr Leu His Leu Asn Lys Gly Thr Pro Ser Gln
                 170                 175                 180

 Ser Pro Val Val Gly Arg Ser Gln Gly Gln Gln Gln Glu Lys Lys
                 185                 190                 195

 Gln Phe Asp Leu Leu Ser Asp Leu Gly Ser Asp Ile Phe Ala Ala
                 200                 205                 210

 Pro Ala Pro Gln Ser Thr Ala Thr Ala Asn Phe Ala Asn Phe Ala
                 215                 220                 225

 His Phe Asn Ser His Ala Ala Gln Asn Ser Ala Asn Ala Asp Phe
                 230                 235                 240

 Ala Asn Phe Asp Ala Phe Gly Gln Ser Ser Gly Ser Ser Asn Phe
                 245                 250                 255

 Gly Gly Phe Pro Thr Ala Ser His Ser Pro Phe Gln Pro Gln Thr
                 260                 265                 270

 Thr Gly Gly Ser Ala Ala Ser Val Asn Ala Asn Phe Ala His Phe
                 275                 280                 285

 Asp Asn Phe Pro Lys Ser Ser Ser Ala Asp Phe Gly Thr Phe Asn
                 290                 295                 300

 Thr Ser Gln Ser His Gln Thr Ala Ser Ala Val Ser Lys Val Ser
                 305                 310                 315

 Thr Asn Lys Ala Gly Leu Gln Thr Ala Asp Lys Tyr Ala Ala Leu
                 320                 325                 330

 Ala Asn Leu Asp Asn Ile Phe Ser Ala Gly Gln Gly Gly Asp Gln
                 335                 340                 345

 Gly Ser Gly Phe Gly Thr Thr Gly Lys Ala Pro Val Gly Ser Val
                 350                 355                 360

 Val Ser Val Pro Ser Gln Ser Ser Ala Ser Ser Asp Lys Tyr Ala
                 365                 370                 375

 Ala Leu Ala Glu Leu Asp Ser Val Phe Ser Ser Ala Ala Thr Ser
                 380                 385                 390

 Ser Asn Ala Tyr Thr Ser Thr Ser Asn Ala Ser Ser Asn Val Phe
                 395                 400                 405

 Gly Thr Val Pro Val Val Ala Ser Ala Gln Thr Gln Pro Ala Ser
                 410                 415                 420

 Ser Ser Val Pro Ala Pro Phe Gly Arg Thr Pro Ser Thr Asn Pro
                 425                 430                 435

 Phe Val Ala Ala Ala Gly Pro Ser Val Ala Ser Ser Thr Asn Pro
                 440                 445                 450

 Phe Gln Thr Asn Ala Arg Gly Ala Thr Ala Ala Thr Phe Gly Thr
                 455                 460                 465

 Ala Ser Met Ser Met Pro Thr Gly Phe Gly Thr Pro Ala Pro Tyr
                 470                 475                 480

 Ser Leu Pro Thr Ser Phe Ser Gly Ser Phe Gln Gln Pro Ala Phe
                 485                 490                 495

 Pro Ala Gln Ala Ala Phe Pro Gln Gln Thr Ala Phe Ser Gln Gln
                 500                 505                 510

 Pro Asn Gly Ala Gly Phe Ala Ala Phe Gly Gln Thr Lys Pro Val
                 515                 520                 525

 Val Thr Pro Phe Gly Gln Val Ala Ala Ala Gly Val Ser Ser Asn
                 530                 535                 540

 Pro Phe Met Thr Gly Ala Pro Thr Gly Gln Phe Pro Thr Gly Ser
                 545                 550                 555

 Ser Ser Thr Asn Pro Phe Leu
                 560

<210> 3161
<211> 3346
<212> DNA
<213> Homo sapien

<400> 3161
 acgtactcca tgcgctacct gctgcccagc gtcgtgctcc tgggcacggc 50

 gcccacctac gtgttggcct ggggggtctg gcggctgctc tccgccttcc 100

 tgcccgcccg cttctaccaa gcgctggacg accggctcta ctgcgtctac 150

 cagagcatgg tgctcttctt cttcgagaat tacaccgggg tccagatatt 200

 gctatatgga gatttgccaa aaaataaaga aaatataata tatttagcaa 250

 atcatcaaag cacagttgac tggattgttg ctgacatctt ggccatcagg 300

 cagaatgcgc taggacatgt gcgctacgtg ctgaaagaag ggttaaaatg 350

 gctgccattg tatgggtgtt actttgctca gcatggagga atctatgtaa 400

 agcgcagtgc caaatttaac gagaaagaga tgcgaaacaa ggtgcagagc 450

 tacgtggacg caggaactcc aatgtatctt gtgatttttc cagaaggtac 500

 aaggtataat ccagagcaaa caaaagtcct ttcagctagt caggcatttg 550

 ctgcccaacg tggccttgca gtattaaaac atgtgctaac accacgaata 600

 aaggcaactc acgttgcttt tgattgcatg aagaattatt tagatgcaat 650

 ttatgatgtt acggtggttt atgaagggaa agacgatgga gggcagcgaa 700

 gagagtcacc gaccatgacg gaatttctct gcaaagaatg tccaaaaatt 750

 catattcaca ttgatcgtat cgacaaaaaa gatgtcccag aagaacaaga 800

 acatatgaga agatggctgc atgaacgttt cgaaatcaaa gataagatgc 850

 ttatagaatt ttatgagtca ccagatccag aaagaagaaa aagatttcct 900

 gggaaaagtg ttaattccaa attaagtatc aagaagactt taccatcaat 950

 gttgatctta agtggtttga ctgcaggcat gcttatgacc gatgctggaa 1000

 ggaagctgta tgtgaacacc tggatatatg gaaccctact tggctgcctg 1050

 tgggttacta ttaaagcata gacaagtagc tgtctccaga cagtgggatg 1100

 tgctacattg tctatttttg gcggctgcac atgacatcaa attgtttcct 1150

 gaatttatta aggagtgtaa ataaagcctt gttgattgaa gattggataa 1200

 tagaatttgt gacgaaagct gatatgcaat ggtcttgggc aaacatacct 1250

 ggttgtacaa ctttagcatc ggggctgctg gaagggtaaa agctaaatgg 1300

 agtttctcct gctctgtcca tttcctatga actaatgaca acttgagaag 1350

 gctgggagga ttgtgtattt tgcaagtcag atggctgcat ttttgagcat 1400

 taatttgcag cgtatttcac tttttctgtt attttcaatt tattacaact 1450

 tgacagctcc aagctcttat tactaaagta tttagtatct tgcagctagt 1500

 taatatttca tcttttgctt atttctacaa gtcagtgaaa taaattgtat 1550

 ttaggaagtg tcaggatgtt caaaggaaag ggtaaaaagt gttcatgggg 1600

 aaaaagctct gtttagcaca tgattttatt gtattgcgtt attagctgat 1650

 tttactcatt ttatatttgc aaaataaatt tctaatattt attgaaattg 1700

 cttaatttgc acaccctgta cacacagaaa atggtataaa atatgagaac 1750

 gaagtttaaa attgtgactc tgattcatta tagcagaact ttaaatttcc 1800

 cagctttttg aagatttaag ctacgctatt agtacttccc tttgtctgtg 1850

 ccataagtgc ttgaaaacgt taaggttttc tgttttgttt tgttttttta 1900

 atatcaaaag agtcggtgtg aaccttggtt ggaccccaag ttcacaagat 1950

 ttttaaggtg atgagagcct gcagacattc tgcctagatt tactagcgtg 2000

 tgccttttgc ctgcttctct ttgatttcac agaatattca ttcagaagtc 2050

 gcgtttctgt agtgtggtgg attcccactg ggctctggtc cttcccttgg 2100

 atcccgtcag tggtgctgct cagcggcttg cacgcagact tgctaggaag 2150

 aaatgcagag ccagcctgtg ctgcccactt tcagagttga actctttaag 2200

 cccttgtgag tgggcttcac cagctactgc agaggcattt tgcatttgtc 2250

 tgtgtcaaga agttcacctt ctcaagccag tgaaatacag acttaatttg 2300

 tcatgactga acgaatttgt ttatttccca ttaggtttag tggagctaca 2350

 cattaatatg tatcgcctta gagcaagagc tgtgttccag gaaccagatc 2400

 acgattttta gccatggaac aatatatccc atgggagaag acctttcagt 2450

 gtgaactgtt ctatttttgt gttataattt aaacttcgat ttcctcatag 2500

 tcctttaagt tgacatttct gcttactgct actggatttt tgctgcagaa 2550

 atgtatcagt ggcccacatt aaacatacca gttggatcat gataagcaaa 2600

 atgaaagaaa taatgattaa gggaaaatta agtgactgtg ttacactgct 2650

 tctcccatgc cagagaataa actctttcaa gcatcatctt tgaagagtcg 2700

 tgtggtgtga attggtttgt gtacattaga atgtatgcac acatccatgg 2750

 acactcagga tatagttggc ctaataatcg gggcatgggt aaaacttatg 2800

 aaaatttcct catgctgaat tgtaattttc tcttacctgt aaagtaaaat 2850

 ttagatcaat tccatgtctt tgttaagtac agggatttaa tatattttga 2900

 atataatggg tatgttctaa atttgaactt tgagaggcaa tactgttgga 2950

 attatgtgga ttctaactca ttttaacaag gtagcctgac ctgcataaga 3000

 tcacttgaat gttaggtttc atagaactat actaatcttc tcacaaaagg 3050

 tctataaaat acagtcgttg aaaaaaattt tgtatcaaaa tgtttggaaa 3100

 attagaagct tctccttaac ctgtattgat actgacttga gttattttct 3150

 aaaattaaga gccgtatacc tacctgtaag tcttttcaca tatcatttaa 3200

 acttttgttt gtattattac tgatttacag cttagttatt aatttttctt 3250

 tataagaatg ccgtcgatgt gcatgctttt atgtttttta gaaaagggtg 3300

 tgtttggatg aaagtaaaaa aaaaaataaa atctttcact gtctct 3346

<210> 3162
<211> 353
<212> PRT
<213> Homo sapien

<400> 3162
 Met Arg Tyr Leu Leu Pro Ser Val Val Leu Leu Gly Thr Ala Pro
   1               5                  10                  15

 Thr Tyr Val Leu Ala Trp Gly Val Trp Arg Leu Leu Ser Ala Phe
                  20                  25                  30

 Leu Pro Ala Arg Phe Tyr Gln Ala Leu Asp Asp Arg Leu Tyr Cys
                  35                  40                  45

 Val Tyr Gln Ser Met Val Leu Phe Phe Phe Glu Asn Tyr Thr Gly
                  50                  55                  60

 Val Gln Ile Leu Leu Tyr Gly Asp Leu Pro Lys Asn Lys Glu Asn
                  65                  70                  75

 Ile Ile Tyr Leu Ala Asn His Gln Ser Thr Val Asp Trp Ile Val
                  80                  85                  90

 Ala Asp Ile Leu Ala Ile Arg Gln Asn Ala Leu Gly His Val Arg
                  95                 100                 105

 Tyr Val Leu Lys Glu Gly Leu Lys Trp Leu Pro Leu Tyr Gly Cys
                 110                 115                 120

 Tyr Phe Ala Gln His Gly Gly Ile Tyr Val Lys Arg Ser Ala Lys
                 125                 130                 135

 Phe Asn Glu Lys Glu Met Arg Asn Lys Val Gln Ser Tyr Val Asp
                 140                 145                 150

 Ala Gly Thr Pro Met Tyr Leu Val Ile Phe Pro Glu Gly Thr Arg
                 155                 160                 165

 Tyr Asn Pro Glu Gln Thr Lys Val Leu Ser Ala Ser Gln Ala Phe
                 170                 175                 180

 Ala Ala Gln Arg Gly Leu Ala Val Leu Lys His Val Leu Thr Pro
                 185                 190                 195

 Arg Ile Lys Ala Thr His Val Ala Phe Asp Cys Met Lys Asn Tyr
                 200                 205                 210

 Leu Asp Ala Ile Tyr Asp Val Thr Val Val Tyr Glu Gly Lys Asp
                 215                 220                 225

 Asp Gly Gly Gln Arg Arg Glu Ser Pro Thr Met Thr Glu Phe Leu
                 230                 235                 240

 Cys Lys Glu Cys Pro Lys Ile His Ile His Ile Asp Arg Ile Asp
                 245                 250                 255

 Lys Lys Asp Val Pro Glu Glu Gln Glu His Met Arg Arg Trp Leu
                 260                 265                 270

 His Glu Arg Phe Glu Ile Lys Asp Lys Met Leu Ile Glu Phe Tyr
                 275                 280                 285

 Glu Ser Pro Asp Pro Glu Arg Arg Lys Arg Phe Pro Gly Lys Ser
                 290                 295                 300

 Val Asn Ser Lys Leu Ser Ile Lys Lys Thr Leu Pro Ser Met Leu
                 305                 310                 315

 Ile Leu Ser Gly Leu Thr Ala Gly Met Leu Met Thr Asp Ala Gly
                 320                 325                 330

 Arg Lys Leu Tyr Val Asn Thr Trp Ile Tyr Gly Thr Leu Leu Gly
                 335                 340                 345

 Cys Leu Trp Val Thr Ile Lys Ala
                 350

<210> 3163
<211> 2168
<212> DNA
<213> Homo sapien

<400> 3163
 ggcacgaggg caccgcgctg cgccgtgccc gtgagtccgg cgcgcagagg 50

 aggaggagaa agctgaccgc ttaggcccgg gtagtggtcg tcgtggtttt 100

 ccttgtagtt cgtggtctga gaccaggcct caagtggaaa cggcgtcacc 150

 atgatcgcac ggcggaaccc agaaccctta cggtttctgc cggatgaggc 200

 ccggagcctg cccccgccca agctgaccga cccgcggctc ctctacatcg 250

 gcttcttggg ctactgctcc ggcctgattg ataacctgat ccggcggagg 300

 ccgatcgcga cggctggttt gcatcgccag cttctatata ttacggcctt 350

 tttttttgct ggatattatc ttgtaaaacg tgaagactac ctgtatgctg 400

 tgagggaccg tgaaatgttt ggatatatga aattacatcc agaggatttt 450

 cctgaagaag ataagaaaac atatggtgaa atttttgaaa aattccatcc 500

 aatacgttga agtcttcaaa atgcttgctc cagtttcact gatacctgct 550

 gtttctgaat ttgatggaac atgtttctta tgacagttga agcttatgct 600

 aatctgtatg ttacaccttg taattaaaat acgtaccatg agtactctga 650

 ctctttattg ttgtaagaaa aatagttcat catcagagaa tggtcagttt 700

 ccattcaccc atctgaaaga ttttaagatg aggttgaatt ctagtttaga 750

 gttagcagac tacccaaatc tggcccactg ccaataaagt ctcattggaa 800

 cacagccatg ctcatttgtt tacatgttgt ttatggcgac tgccatgctg 850

 caagagcaga attgagtagt tgtgatagag acctatggcc tgcaaagcct 900

 aattaatatg tagccctttc agaaaaggtt tgcctgcccc tgtcctagtg 950

 caaagtgaat ttagagtgag ccagattatg gaggattctg tgactcttgc 1000

 caaataattt tgacttcatc ctgtaggtat taagtcatta aggcgtttta 1050

 aatcatacag tcaggtttgt atttctgagc tgtctataat gaatgatata 1100

 gaaggtggtt tcgaaggagg agactccaga caaggaaaac agaaatctta 1150

 tgttgccaag ttgtctttgc tcttaggtgg gttatcctgg agaaaatgga 1200

 ctcaggagct aatactgtct acagtggagc ttggtgcaat tagaagcaaa 1250

 agactgtacc taactggaat gaggttactt tttatggctt atcaaatgct 1300

 tgtcctggcc cgatgcagtg gctcatgcct gtaatcccag cactttgaga 1350

 ggctgaggca gggcagattg catgagccca ggagttcgag accaacttgg 1400

 gcaacatggt gaaacactgt ctctacataa aatacaaaaa ttagctgggc 1450

 gtggtggcac gttcctgcaa tcccagctac tcataaggct gaggtgggag 1500

 gatctattga gccctggaat tcgaggatgc aattaattgt ggttgtgtca 1550

 cagttcactg cagcctgggt gacactccag cctgggtgac aaaggagacc 1600

 ccgtcaaaaa aaaaagtact tgtcccaaaa gtttttgttt cctagcttag 1650

 aatttataat cagattaggt tttggagata aagtatatgt ggtatttttt 1700

 tttttttttt gagacagtct tgctctgtca tcaggctgga gtgcagtggc 1750

 gcaatttcgg ctcactgcaa cctccacctc ctgggttcaa gcaattctcc 1800

 tgcctcagcc tcccgagtag ctgggactac aggtgcatgc cacgacgccc 1850

 agctgatttt tgtgttttta gtagagacgg ggtttcacca tgttggccaa 1900

 gatggtctca atctcttgac cttgtgatcc acctgccttg gccttccaaa 1950

 gtgttggaat tacaggcgtg agccaccgcg cctggtctat atgtgatttc 2000

 aaattaggtg gccttataaa tataagcaga tggtttctgg gcaaaatcaa 2050

 atgatttctg tctctatttt cttgagtacc aattgtaaaa actgaaatta 2100

 ggttgaggaa agtgctttag aaataataaa gatgtacaaa taaaaaaaaa 2150

 aaaaaaaaaa aaaaaaaa 2168

<210> 3164
<211> 119
<212> PRT
<213> Homo sapien

<400> 3164
 Met Ile Ala Arg Arg Asn Pro Glu Pro Leu Arg Phe Leu Pro Asp
   1               5                  10                  15

 Glu Ala Arg Ser Leu Pro Pro Pro Lys Leu Thr Asp Pro Arg Leu
                  20                  25                  30

 Leu Tyr Ile Gly Phe Leu Gly Tyr Cys Ser Gly Leu Ile Asp Asn
                  35                  40                  45

 Leu Ile Arg Arg Arg Pro Ile Ala Thr Ala Gly Leu His Arg Gln
                  50                  55                  60

 Leu Leu Tyr Ile Thr Ala Phe Phe Phe Ala Gly Tyr Tyr Leu Val
                  65                  70                  75

 Lys Arg Glu Asp Tyr Leu Tyr Ala Val Arg Asp Arg Glu Met Phe
                  80                  85                  90

 Gly Tyr Met Lys Leu His Pro Glu Asp Phe Pro Glu Glu Asp Lys
                  95                 100                 105

 Lys Thr Tyr Gly Glu Ile Phe Glu Lys Phe His Pro Ile Arg
                 110                 115

<210> 3165
<211> 1375
<212> DNA
<213> Homo sapien

<400> 3165
 cccaaagtag gctaggccta cggaagctgg gtcttcttgc tgtgagcgcg 50

 gagtcgcggc gggtagggcg gcgtcgcgtg cgtgacgtca tccagcggcg 100

 cctcgcgagg ctccagtggc cttgacctcc cgcggcgtgg gaggctgcgc 150

 ggcgatgctg cagttcgtcc gggccggggc gcgggcctgg cttcggccta 200

 ccggcagcca gggcctgagt tccctggcgg aagaggcagc gcgtgcgacc 250

 gagaacccgg agcaggtggc gagcgagggt ctcccggagc ccgtgctgcg 300

 caaagtcgag ctcccggtac ccactcatcg acgcccagtg caggcctggg 350

 tcgagtcctt gcggggcttc gagcaggagc gcgtgggcct ggccgacctg 400

 caccccgatg ttttcgccac cgcgcccagg ctggacatac tgcaccaggt 450

 tgctatgtgg cagaagaact tcaagagaat tagctatgcc aagaccaaga 500

 cgagagccga ggtgcggggc ggtggccgga agccttggcc gcagaaaggc 550

 actgggcggg cccggcatgg cagcatccgc tctccgctct ggcgaggagg 600

 aggtgttgcc catggccccc ggggccccac aagttactac tacatgctgc 650

 ccatgaaggt gcgggcgctg ggtctcaaag tggcactgac cgtcaagctg 700

 gcccaggacg acctgcacat catggactcc ctagagctgc ccaccggaga 750

 cccacagtac ctgacagagc tggcgcacta ccgccgctgg ggggactccg 800

 tactcctcgt ggacttaaca cacgaggaga tgccacagag catcgtggag 850

 gccacctcta ggcttaagac cttcaacttg atcccggctg ttggcctaaa 900

 tgtgcacagc atgctcaagc accagacgct ggtcctgacg ctgcccaccg 950

 tcgccttcct ggaggacaag ctgctctggc aggactcacg ttacagaccc 1000

 ctctacccct tcagcctgcc ctacagcgac ttcccccgac ccctacccca 1050

 cgctacccag ggcccagcgg ccaccccgta ccactgttga tgtgaagcac 1100

 ctcttctgag ccaggccgag cccctggccg acttgggagc ctcaggccca 1150

 cgcccaccct tcgaggaagg tgtcacctgg accccttcat tccacggagg 1200

 aagctgaggc cacagggagc ggccatcgcc attgggaagg ggcgactcca 1250

 cggaaagccc agacgggctt ctgcatccat tccctctttt tgtttttaaa 1300

 ataaattgta tttttgaatc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1350

 aaaaaaaaaa aaaaaaaaaa aaaaa 1375

<210> 3166
<211> 311
<212> PRT
<213> Homo sapien

<400> 3166
 Met Leu Gln Phe Val Arg Ala Gly Ala Arg Ala Trp Leu Arg Pro
   1               5                  10                  15

 Thr Gly Ser Gln Gly Leu Ser Ser Leu Ala Glu Glu Ala Ala Arg
                  20                  25                  30

 Ala Thr Glu Asn Pro Glu Gln Val Ala Ser Glu Gly Leu Pro Glu
                  35                  40                  45

 Pro Val Leu Arg Lys Val Glu Leu Pro Val Pro Thr His Arg Arg
                  50                  55                  60

 Pro Val Gln Ala Trp Val Glu Ser Leu Arg Gly Phe Glu Gln Glu
                  65                  70                  75

 Arg Val Gly Leu Ala Asp Leu His Pro Asp Val Phe Ala Thr Ala
                  80                  85                  90

 Pro Arg Leu Asp Ile Leu His Gln Val Ala Met Trp Gln Lys Asn
                  95                 100                 105

 Phe Lys Arg Ile Ser Tyr Ala Lys Thr Lys Thr Arg Ala Glu Val
                 110                 115                 120

 Arg Gly Gly Gly Arg Lys Pro Trp Pro Gln Lys Gly Thr Gly Arg
                 125                 130                 135

 Ala Arg His Gly Ser Ile Arg Ser Pro Leu Trp Arg Gly Gly Gly
                 140                 145                 150

 Val Ala His Gly Pro Arg Gly Pro Thr Ser Tyr Tyr Tyr Met Leu
                 155                 160                 165

 Pro Met Lys Val Arg Ala Leu Gly Leu Lys Val Ala Leu Thr Val
                 170                 175                 180

 Lys Leu Ala Gln Asp Asp Leu His Ile Met Asp Ser Leu Glu Leu
                 185                 190                 195

 Pro Thr Gly Asp Pro Gln Tyr Leu Thr Glu Leu Ala His Tyr Arg
                 200                 205                 210

 Arg Trp Gly Asp Ser Val Leu Leu Val Asp Leu Thr His Glu Glu
                 215                 220                 225

 Met Pro Gln Ser Ile Val Glu Ala Thr Ser Arg Leu Lys Thr Phe
                 230                 235                 240

 Asn Leu Ile Pro Ala Val Gly Leu Asn Val His Ser Met Leu Lys
                 245                 250                 255

 His Gln Thr Leu Val Leu Thr Leu Pro Thr Val Ala Phe Leu Glu
                 260                 265                 270

 Asp Lys Leu Leu Trp Gln Asp Ser Arg Tyr Arg Pro Leu Tyr Pro
                 275                 280                 285

 Phe Ser Leu Pro Tyr Ser Asp Phe Pro Arg Pro Leu Pro His Ala
                 290                 295                 300

 Thr Gln Gly Pro Ala Ala Thr Pro Tyr His Cys
                 305                 310

<210> 3167
<211> 3088
<212> DNA
<213> Homo sapien

<400> 3167
 cgcgccaggg aggttgtcgg gaggggccgg cgaataaaac gagcggcgaa 50

 agaaccgaaa aaaggctcga cgctaccgtg tatgaggaac tttgatcctt 100

 gcgggccacc attccggaag tagaatttag aggaagaaaa taccggagtt 150

 gcagggtata ggtaaatttc tcaaggttat aggttggggt tcttagaact 200

 ttttgtggtg tgtgttggcc tagagcgact cagaagcgtt agtgacttca 250

 cctaaaaaag ctaacctctc tgctgagcgc gaccggtatg cggcgcagga 300

 tgagcctcag ggcttctgtt aagagtctgt ctgagaaagc cggtctgcgc 350

 tgttcctcgg tggcgacctt aattatgaga tgagctaatg ctttactgac 400

 ttaaccatgg cgcagcgggc agtgtggctc ataagccacg aaccgggaac 450

 tccactttgt ggcaccgtga gattctccag acggtatcca actgttgaaa 500

 aacgagccag agtcttcaat ggagcaagtt atgtgcctgt tcctgaagat 550

 ggtccctttc ttaaagcact gctctttgaa cttagattat tggatgatga 600

 taaagacttc gttgagagtc gtgatagctg ttcacgcatc aataaaacat 650

 ccatttatgg actcctgata ggaggtgaag aactctggcc agttgttgct 700

 tttctgaaga atgacatgat atatgcttgt gttccactag ttgaacaaac 750

 tctgtcccct cgtccgccac taattagtgt cagtggagtt tcacaaggct 800

 ttgaatttct ttttgggata caggattttc tttattcagg tcaaaaaaat 850

 gactctgagc tgaatacaaa attgagccag ttgcctgact tgcttctgca 900

 ggcttgtcca tttggtactt tattagatgc caacttacag aattcattag 950

 ataataccaa ttttgcatct gtgactcagc cacagaaaca gccagcttgg 1000

 aaaactggga cgtacaaagg aaaaccacaa gtttctattt ctatcactga 1050

 aaaggtaaaa tccatgcaat atgataaaca gggtatagca gatacatggc 1100

 aagttgttgg aacagtgact tgcaagtgtg atttggaagg aatcatgcca 1150

 aatgttacca tcagcttgag tctccccacc aatggatctc cacttcagga 1200

 tattctagtt cacccttgtg taacttctct tgactctgca attctgactt 1250

 ctagtagtat tgatgcaatg gatgactctg catttagtgg gccttacaaa 1300

 tttccattca ctccaccttt agagtcattc aacttatgct tctacacttc 1350

 ccaggtccct gccccaccaa ttttgggttt ttatcaaatg aaggaggaag 1400

 aagtacaact aagaataacc attaatttaa aacttcatga aagtgtgaaa 1450

 aataattttg aattctgtga agcccatata cctttttaca atagaggtcc 1500

 aattacacat ttggaataca aaactagttt tggccagctt gaagtatttc 1550

 gagagaaaag cttattgatc tggattattg gccagaagtt cccaaaatca 1600

 atggaaatta gtctttctgg aactgtaact tttggagcca agagccatga 1650

 gaagcagcca tttgacccaa tttgtactgg agaaacagca tatttaaagc 1700

 ttcattttag gatcttagat tacacactta ctggatgtta tgcagatcag 1750

 cattcagttc aagtttttgc atcaggaaaa ccaaaaataa gtgcacaccg 1800

 gaaactaatt tcttctgatt attacatctg gaattctaaa gcccctgctc 1850

 cagtaacata tggatcatta ttattgtaat agtctcatgt ttaaatggga 1900

 ttatataatg ataacagttt aaagaaaatc ataatcttat atttttaatg 1950

 tggatgcata taacctgtga gtgaaaaatc actgaatgat ttaattgtaa 2000

 aagtagtctt atgtggtgtt tgtagtctga tagagcttga aaggacattt 2050

 taaaagctaa tgtctccaat tttgtcaacc ttcgatttta tgccagtata 2100

 attcagaaca tagaaaagta atgattcact tgggctcatt ttagactggt 2150

 cctgggtcac cctgccacac ttgtttccta gtgtttctgt ggcagacatt 2200

 gctaatcaat tacagccctt ttctgtactg agccttggat aaagggtcag 2250

 gctccttttt agttcagaga ttcaggcagc cactcccagt gggttgtaga 2300

 taatgtgcaa gataaaaact attttctctt ccaaatctaa gtactaagct 2350

 cctagtataa ggtgttgtta cagaatacca gagaccatgt tagagacaac 2400

 tacatctctt caaaaaacag ccaacagaga caaaggaaaa gtgtttaaat 2450

 agtaagctgt tcttcttaat cagaactatc ctattgacta ataaataatc 2500

 tgcataattc tacttaaggt gtgtaatctc tgttctagag ttagttttta 2550

 agtaagcttg ttaatctgcc actttgacat tttgcttagg atgtcagtag 2600

 ccatattaag atgtgtagaa taccttcaga agatgatcat agtgttttgt 2650

 aatcatttaa tgtctgcagc caaattttta aaggtaattt agacctaata 2700

 ctgctcttgc tgtgtcttat taagttaaaa ttaatgaatg aattctggta 2750

 aaaattcaaa aggcactctg tgagtagaga gtatcattta agcttatttt 2800

 agtcacatgt agtatatatc tccttaaagc tgtcactctc actttcttac 2850

 cattctcttg atttcttcag aaaccatcta gtcatcatct ttatactcta 2900

 cctgcttctg caattatata tcatattatg ttttcagagc agttcattgt 2950

 caagttggac tttaagtgac cattcaagaa aagatgaaat ctcacgaacc 3000

 tcaaaacttc attcatgtct ttttacaaat gagaaaaaaa aatgcattaa 3050

 agattaatac tcaatttgaa aaaaaaaaaa aaaaaaaa 3088

<210> 3168
<211> 490
<212> PRT
<213> Homo sapien

<400> 3168
 Met Ala Gln Arg Ala Val Trp Leu Ile Ser His Glu Pro Gly Thr
   1               5                  10                  15

 Pro Leu Cys Gly Thr Val Arg Phe Ser Arg Arg Tyr Pro Thr Val
                  20                  25                  30

 Glu Lys Arg Ala Arg Val Phe Asn Gly Ala Ser Tyr Val Pro Val
                  35                  40                  45

 Pro Glu Asp Gly Pro Phe Leu Lys Ala Leu Leu Phe Glu Leu Arg
                  50                  55                  60

 Leu Leu Asp Asp Asp Lys Asp Phe Val Glu Ser Arg Asp Ser Cys
                  65                  70                  75

 Ser Arg Ile Asn Lys Thr Ser Ile Tyr Gly Leu Leu Ile Gly Gly
                  80                  85                  90

 Glu Glu Leu Trp Pro Val Val Ala Phe Leu Lys Asn Asp Met Ile
                  95                 100                 105

 Tyr Ala Cys Val Pro Leu Val Glu Gln Thr Leu Ser Pro Arg Pro
                 110                 115                 120

 Pro Leu Ile Ser Val Ser Gly Val Ser Gln Gly Phe Glu Phe Leu
                 125                 130                 135

 Phe Gly Ile Gln Asp Phe Leu Tyr Ser Gly Gln Lys Asn Asp Ser
                 140                 145                 150

 Glu Leu Asn Thr Lys Leu Ser Gln Leu Pro Asp Leu Leu Leu Gln
                 155                 160                 165

 Ala Cys Pro Phe Gly Thr Leu Leu Asp Ala Asn Leu Gln Asn Ser
                 170                 175                 180

 Leu Asp Asn Thr Asn Phe Ala Ser Val Thr Gln Pro Gln Lys Gln
                 185                 190                 195

 Pro Ala Trp Lys Thr Gly Thr Tyr Lys Gly Lys Pro Gln Val Ser
                 200                 205                 210

 Ile Ser Ile Thr Glu Lys Val Lys Ser Met Gln Tyr Asp Lys Gln
                 215                 220                 225

 Gly Ile Ala Asp Thr Trp Gln Val Val Gly Thr Val Thr Cys Lys
                 230                 235                 240

 Cys Asp Leu Glu Gly Ile Met Pro Asn Val Thr Ile Ser Leu Ser
                 245                 250                 255

 Leu Pro Thr Asn Gly Ser Pro Leu Gln Asp Ile Leu Val His Pro
                 260                 265                 270

 Cys Val Thr Ser Leu Asp Ser Ala Ile Leu Thr Ser Ser Ser Ile
                 275                 280                 285

 Asp Ala Met Asp Asp Ser Ala Phe Ser Gly Pro Tyr Lys Phe Pro
                 290                 295                 300

 Phe Thr Pro Pro Leu Glu Ser Phe Asn Leu Cys Phe Tyr Thr Ser
                 305                 310                 315

 Gln Val Pro Ala Pro Pro Ile Leu Gly Phe Tyr Gln Met Lys Glu
                 320                 325                 330

 Glu Glu Val Gln Leu Arg Ile Thr Ile Asn Leu Lys Leu His Glu
                 335                 340                 345

 Ser Val Lys Asn Asn Phe Glu Phe Cys Glu Ala His Ile Pro Phe
                 350                 355                 360

 Tyr Asn Arg Gly Pro Ile Thr His Leu Glu Tyr Lys Thr Ser Phe
                 365                 370                 375

 Gly Gln Leu Glu Val Phe Arg Glu Lys Ser Leu Leu Ile Trp Ile
                 380                 385                 390

 Ile Gly Gln Lys Phe Pro Lys Ser Met Glu Ile Ser Leu Ser Gly
                 395                 400                 405

 Thr Val Thr Phe Gly Ala Lys Ser His Glu Lys Gln Pro Phe Asp
                 410                 415                 420

 Pro Ile Cys Thr Gly Glu Thr Ala Tyr Leu Lys Leu His Phe Arg
                 425                 430                 435

 Ile Leu Asp Tyr Thr Leu Thr Gly Cys Tyr Ala Asp Gln His Ser
                 440                 445                 450

 Val Gln Val Phe Ala Ser Gly Lys Pro Lys Ile Ser Ala His Arg
                 455                 460                 465

 Lys Leu Ile Ser Ser Asp Tyr Tyr Ile Trp Asn Ser Lys Ala Pro
                 470                 475                 480

 Ala Pro Val Thr Tyr Gly Ser Leu Leu Leu
                 485                 490

<210> 3169
<211> 1668
<212> DNA
<213> Homo sapien

<400> 3169
 ggcgaaggag atcagcagga cgctgcgcac aacatgggca accacctgcc 50

 gctcctgcct gcagagagtg aggaagaaga tgaaatggaa gttgaagacc 100

 aggatagtaa agaagccaaa aaaccaaaca tcataaattt tgacaccagt 150

 ctgccgacat cacatacata cctaggtgct gatatggaag aatttcatgg 200

 caggactttg cacgatgacg acagctgtca ggtgattcca gttcttccac 250

 aagtgatgat gatcctgatt cccggacaga cattacctct tcagcttttt 300

 caccctcaag aagtcagtat ggtgcggaat ttaattcaga aagatagaac 350

 ctttgctgtt cttgcataca gcaatgtaca ggaaagggaa gcacagtttg 400

 gaacaacagc agagatatat gcctatcgag aagaacagga ttttggaatt 450

 gagatagtga aagtgaaagc aattggaaga caaaggttca aagtccttga 500

 gctaagaaca cagtcagatg gaatccagca agctaaagtg caaattcttc 550

 ccgaatgtgt gttgccttca accatgtctg cagttcaatt agaatccctc 600

 aataagtgcc agatatttcc ttcaaaacct gtctcaagag aagaccaatg 650

 ttcatataaa tggtggcaga aataccagaa gagaaagttt cattgtgcaa 700

 atctaacttc atggcctcgc tggctgtatt ccttatatga tgctgagacc 750

 ttaatggaca gaatcaagaa acagctacgt gaatgggatg aaaatctaaa 800

 agatgattct cttccttcaa atccaataga tttttcttac agagtagctg 850

 cttgtcttcc tattgatgat gtattgagaa ttcagctcct taaaattggc 900

 agtgctatcc agcgacttcg ctgtgaatta gacattatga ataaatgtac 950

 ttccctttgc tgtaaacaat gtcaagaaac agaaataaca accaaaaatg 1000

 aaatattcag tttatcctta tgtgggccga tggagcttat gtgaatcctc 1050

 atggatatgt gcatgagaca cttactgtgt ataaggcttg caacttgaat 1100

 ctgataggcc ggccttctac agaacacagc tggtttcctg ggtatgcctg 1150

 gactgttgcc cagtgtaaga tctgtgcaag cccatattgg atgggaagtt 1200

 tacggccacc aaaaaagaca tgtcacctca aaaattttgg ggcttaacgc 1250

 gatctgctct gttgcccacg atcccagaca ctgaagatga aataagtcca 1300

 gacaaagtaa tactttgctt gtaaacagat gtgatagaga taaagttatc 1350

 taacaaattg gttatattct aagatctgct ttggaaatta ttgcctctga 1400

 tacataccta agtaaacata acattaatac ctaagtaaac ataacattac 1450

 ttggagggtt gcagtttcta agtgaaactg tatttgaaac ttttaagtat 1500

 actttaggaa acaagcatga acggcagtct agaataccag aaacatctac 1550

 ttgggtagct tggtgccatt atcctgtgga atctgatatg tctggtagca 1600

 tgtcattgat gggacatgaa gacatctttg gaaatgatga gattatttcc 1650

 tgtgttaaaa aaaaaaaa 1668

<210> 3170
<211> 336
<212> PRT
<213> Homo sapien

<400> 3170
 Met Gly Asn His Leu Pro Leu Leu Pro Ala Glu Ser Glu Glu Glu
   1               5                  10                  15

 Asp Glu Met Glu Val Glu Asp Gln Asp Ser Lys Glu Ala Lys Lys
                  20                  25                  30

 Pro Asn Ile Ile Asn Phe Asp Thr Ser Leu Pro Thr Ser His Thr
                  35                  40                  45

 Tyr Leu Gly Ala Asp Met Glu Glu Phe His Gly Arg Thr Leu His
                  50                  55                  60

 Asp Asp Asp Ser Cys Gln Val Ile Pro Val Leu Pro Gln Val Met
                  65                  70                  75

 Met Ile Leu Ile Pro Gly Gln Thr Leu Pro Leu Gln Leu Phe His
                  80                  85                  90

 Pro Gln Glu Val Ser Met Val Arg Asn Leu Ile Gln Lys Asp Arg
                  95                 100                 105

 Thr Phe Ala Val Leu Ala Tyr Ser Asn Val Gln Glu Arg Glu Ala
                 110                 115                 120

 Gln Phe Gly Thr Thr Ala Glu Ile Tyr Ala Tyr Arg Glu Glu Gln
                 125                 130                 135

 Asp Phe Gly Ile Glu Ile Val Lys Val Lys Ala Ile Gly Arg Gln
                 140                 145                 150

 Arg Phe Lys Val Leu Glu Leu Arg Thr Gln Ser Asp Gly Ile Gln
                 155                 160                 165

 Gln Ala Lys Val Gln Ile Leu Pro Glu Cys Val Leu Pro Ser Thr
                 170                 175                 180

 Met Ser Ala Val Gln Leu Glu Ser Leu Asn Lys Cys Gln Ile Phe
                 185                 190                 195

 Pro Ser Lys Pro Val Ser Arg Glu Asp Gln Cys Ser Tyr Lys Trp
                 200                 205                 210

 Trp Gln Lys Tyr Gln Lys Arg Lys Phe His Cys Ala Asn Leu Thr
                 215                 220                 225

 Ser Trp Pro Arg Trp Leu Tyr Ser Leu Tyr Asp Ala Glu Thr Leu
                 230                 235                 240

 Met Asp Arg Ile Lys Lys Gln Leu Arg Glu Trp Asp Glu Asn Leu
                 245                 250                 255

 Lys Asp Asp Ser Leu Pro Ser Asn Pro Ile Asp Phe Ser Tyr Arg
                 260                 265                 270

 Val Ala Ala Cys Leu Pro Ile Asp Asp Val Leu Arg Ile Gln Leu
                 275                 280                 285

 Leu Lys Ile Gly Ser Ala Ile Gln Arg Leu Arg Cys Glu Leu Asp
                 290                 295                 300

 Ile Met Asn Lys Cys Thr Ser Leu Cys Cys Lys Gln Cys Gln Glu
                 305                 310                 315

 Thr Glu Ile Thr Thr Lys Asn Glu Ile Phe Ser Leu Ser Leu Cys
                 320                 325                 330

 Gly Pro Met Glu Leu Met
                 335

<210> 3171
<211> 2229
<212> DNA
<213> Homo sapien

<400> 3171
 tttcacctca gcaaggccag gggatctgca cgttgtgtta gacatggcta 50

 aagtagctga taccatcctg ttcctccttg atccactaga aggctgggac 100

 agcaccggtg attactgtct ttcctgcctc tttgctcagg gccttccgac 150

 ctatacacta gctgtccagg ggatttctgg cctcccactg aagaaacaaa 200

 tagataccag gaagaagcta agtaaagcag tggagaagcg ctttccgcat 250

 gacaaactcc tcttgttaga cactcaacag gaggcaggga tgctgcttag 300

 gcagttggct aaccagaagc aacagcatct tgcttttcga gatcggcggg 350

 cctacctatt tgcccatgct gttgattttg ttcctagtga agagaataac 400

 ttggtgggca ccttgaaaat ttcaggctat gttcgagggc agactctgaa 450

 tgtcaatagg ttgctgcata tcgttggata tggtgatttc cagatgaaac 500

 agatagatgc ccccggagac cctttccctt taaatcctag aggaattaaa 550

 ccccaaaagg acccagacat ggcaatggag atttgtgcta cggatgctgt 600

 agatgatatg gaagaaggtc ttaaagtcct aatgaaggca gacccttgta 650

 gacaggaatc cttgcaagca gaggttatcc cagatccaat ggagggagag 700

 caaacctggc ccactgagga ggagctgagc gaggcaaagg atttcttgaa 750

 ggaaagttct aaggtggtaa agaaggtccc caaaggaaca tccagttacc 800

 aagctgaatg gattttggat ggtggcagcc aaagtggtgg ggaaggagat 850

 gaatatgaat atgatgatat ggaacatgag gattttatgg aggaggaatc 900

 tcaggatgag agtagtgaag aagaggaaga atatgaaact atgactattg 950

 gggagtctgt gcatgatgat ctgtatgata agaaagtaga tgaagaagct 1000

 gaggcaaaaa tgttggagaa atataaacaa gaaagactgg aagagatgtt 1050

 tccagatgaa gtggacacgc cccgtgatgt ggctgctcga attcgatttc 1100

 agaaatacag aggccttaag agcttccgga catctccatg ggatcctaag 1150

 gaaaaccttc ctcaagatta tgctcgaata tttcagtttc agaactttac 1200

 taacactagg aaaagcatct ttaaagaggt tgaagaaaaa gaggttgaag 1250

 gagctgaggt tggctggtat gtcacacttc atgtctctga agtccccgtc 1300

 tcagtggtcg agtgcttcag gcaaggaaca cccttgattg cattttcttt 1350

 actacctcat gaacagaaga tgtcagtatt gaatatggtg gtgaggcgtg 1400

 accctggcaa cactgaacct gtgaaagcca aggaggagct catatttcac 1450

 tgtggattca ggcgcttccg agcctcacct ttattctctc agcacactgc 1500

 agcggacaaa cataaattgc agagattcct gactgctgac atggccctgg 1550

 tggcgacagt ctatgcgcca atcacttttc ctcctgcatc tgtgctgctt 1600

 ttcaagcaga aaagcaatgg aatgcacagc ctcattgcta caggccatct 1650

 tatgtcagta gatccagaca gaatggtcat caagagagtt gttctgagtg 1700

 gtcatccttt caaaattttt actaagatgg cagtagtacg ttacatgttc 1750

 ttcaacagag aggatgtgct gtggtttaaa ccagtggaac tgagaacgaa 1800

 gtggggccgg agaggacata tcaaggaacc tttaggtacc catggccaca 1850

 tgaaatgcag ctttgatggg aagctaaaat ctcaagacac agtactgatg 1900

 aacctgtata aacgagtctt ccccaaatgg acttatgatc catatgtacc 1950

 agaaccagta ccctggctga aaagtgagat ttcttcaaca gtgcctcaag 2000

 ggggcatgga gtaatggatt caaagagatt ctgtcctacc ggtgccagtc 2050

 agtactccag ggatgggagg cacaagttgt gattgggcaa agtttatttt 2100

 ctatgtcagc ctgtcagtcc actgccccat tttgcaagac ttttttttag 2150

 ccttgacaaa atgtctcagt taagtataaa agtttttcca ctacttagtc 2200

 caaaaaaaac tattaaatct taatgaaat 2229

<210> 3172
<211> 656
<212> PRT
<213> Homo sapien

<400> 3172
 Met Ala Lys Val Ala Asp Thr Ile Leu Phe Leu Leu Asp Pro Leu
   1               5                  10                  15

 Glu Gly Trp Asp Ser Thr Gly Asp Tyr Cys Leu Ser Cys Leu Phe
                  20                  25                  30

 Ala Gln Gly Leu Pro Thr Tyr Thr Leu Ala Val Gln Gly Ile Ser
                  35                  40                  45

 Gly Leu Pro Leu Lys Lys Gln Ile Asp Thr Arg Lys Lys Leu Ser
                  50                  55                  60

 Lys Ala Val Glu Lys Arg Phe Pro His Asp Lys Leu Leu Leu Leu
                  65                  70                  75

 Asp Thr Gln Gln Glu Ala Gly Met Leu Leu Arg Gln Leu Ala Asn
                  80                  85                  90

 Gln Lys Gln Gln His Leu Ala Phe Arg Asp Arg Arg Ala Tyr Leu
                  95                 100                 105

 Phe Ala His Ala Val Asp Phe Val Pro Ser Glu Glu Asn Asn Leu
                 110                 115                 120

 Val Gly Thr Leu Lys Ile Ser Gly Tyr Val Arg Gly Gln Thr Leu
                 125                 130                 135

 Asn Val Asn Arg Leu Leu His Ile Val Gly Tyr Gly Asp Phe Gln
                 140                 145                 150

 Met Lys Gln Ile Asp Ala Pro Gly Asp Pro Phe Pro Leu Asn Pro
                 155                 160                 165

 Arg Gly Ile Lys Pro Gln Lys Asp Pro Asp Met Ala Met Glu Ile
                 170                 175                 180

 Cys Ala Thr Asp Ala Val Asp Asp Met Glu Glu Gly Leu Lys Val
                 185                 190                 195

 Leu Met Lys Ala Asp Pro Cys Arg Gln Glu Ser Leu Gln Ala Glu
                 200                 205                 210

 Val Ile Pro Asp Pro Met Glu Gly Glu Gln Thr Trp Pro Thr Glu
                 215                 220                 225

 Glu Glu Leu Ser Glu Ala Lys Asp Phe Leu Lys Glu Ser Ser Lys
                 230                 235                 240

 Val Val Lys Lys Val Pro Lys Gly Thr Ser Ser Tyr Gln Ala Glu
                 245                 250                 255

 Trp Ile Leu Asp Gly Gly Ser Gln Ser Gly Gly Glu Gly Asp Glu
                 260                 265                 270

 Tyr Glu Tyr Asp Asp Met Glu His Glu Asp Phe Met Glu Glu Glu
                 275                 280                 285

 Ser Gln Asp Glu Ser Ser Glu Glu Glu Glu Glu Tyr Glu Thr Met
                 290                 295                 300

 Thr Ile Gly Glu Ser Val His Asp Asp Leu Tyr Asp Lys Lys Val
                 305                 310                 315

 Asp Glu Glu Ala Glu Ala Lys Met Leu Glu Lys Tyr Lys Gln Glu
                 320                 325                 330

 Arg Leu Glu Glu Met Phe Pro Asp Glu Val Asp Thr Pro Arg Asp
                 335                 340                 345

 Val Ala Ala Arg Ile Arg Phe Gln Lys Tyr Arg Gly Leu Lys Ser
                 350                 355                 360

 Phe Arg Thr Ser Pro Trp Asp Pro Lys Glu Asn Leu Pro Gln Asp
                 365                 370                 375

 Tyr Ala Arg Ile Phe Gln Phe Gln Asn Phe Thr Asn Thr Arg Lys
                 380                 385                 390

 Ser Ile Phe Lys Glu Val Glu Glu Lys Glu Val Glu Gly Ala Glu
                 395                 400                 405

 Val Gly Trp Tyr Val Thr Leu His Val Ser Glu Val Pro Val Ser
                 410                 415                 420

 Val Val Glu Cys Phe Arg Gln Gly Thr Pro Leu Ile Ala Phe Ser
                 425                 430                 435

 Leu Leu Pro His Glu Gln Lys Met Ser Val Leu Asn Met Val Val
                 440                 445                 450

 Arg Arg Asp Pro Gly Asn Thr Glu Pro Val Lys Ala Lys Glu Glu
                 455                 460                 465

 Leu Ile Phe His Cys Gly Phe Arg Arg Phe Arg Ala Ser Pro Leu
                 470                 475                 480

 Phe Ser Gln His Thr Ala Ala Asp Lys His Lys Leu Gln Arg Phe
                 485                 490                 495

 Leu Thr Ala Asp Met Ala Leu Val Ala Thr Val Tyr Ala Pro Ile
                 500                 505                 510

 Thr Phe Pro Pro Ala Ser Val Leu Leu Phe Lys Gln Lys Ser Asn
                 515                 520                 525

 Gly Met His Ser Leu Ile Ala Thr Gly His Leu Met Ser Val Asp
                 530                 535                 540

 Pro Asp Arg Met Val Ile Lys Arg Val Val Leu Ser Gly His Pro
                 545                 550                 555

 Phe Lys Ile Phe Thr Lys Met Ala Val Val Arg Tyr Met Phe Phe
                 560                 565                 570

 Asn Arg Glu Asp Val Leu Trp Phe Lys Pro Val Glu Leu Arg Thr
                 575                 580                 585

 Lys Trp Gly Arg Arg Gly His Ile Lys Glu Pro Leu Gly Thr His
                 590                 595                 600

 Gly His Met Lys Cys Ser Phe Asp Gly Lys Leu Lys Ser Gln Asp
                 605                 610                 615

 Thr Val Leu Met Asn Leu Tyr Lys Arg Val Phe Pro Lys Trp Thr
                 620                 625                 630

 Tyr Asp Pro Tyr Val Pro Glu Pro Val Pro Trp Leu Lys Ser Glu
                 635                 640                 645

 Ile Ser Ser Thr Val Pro Gln Gly Gly Met Glu
                 650                 655

<210> 3173
<211> 2056
<212> DNA
<213> Homo sapien

<400> 3173
 tcgcagacag ctcgggggaa cagtggcggc ttcggccggc ggtccttgcg 50

 ctccccaaca gcggcgcggg cgggtgagcc gtcggggcac agtcccggtg 100

 ctcttctgtt tctcagtctt cgcgcgaccc tcgtgcggtg ccacacgggg 150

 cgggctacga gctgctcatc cagaagttcc tcagcctgta cggcgaccag 200

 atcgacatgc accgcaaatt cgtggtgcag ctgttcgccg aggagtgggg 250

 ccagtacgtg gacttgccca agggtttcgc ggtgagcgag cgctgcaagg 300

 tgcgcctcgt gccgctgcag atccagctca ctaccctggg aaatcttaca 350

 ccttcaagca ctgtgttttt ctgctgtgat atgcaggaaa ggttcagacc 400

 agccatcaag tattttgggg atattattag cgtgggacag agattgttgc 450

 aaggggcccg gattttagga attcctgtta ttgtaacaga acaataccct 500

 aaaggtcttg ggagcacggt tcaagaaatt gatttaacag gtgtaaaact 550

 ggtacttcca aagaccaagt tttcaatggt attaccagaa gtagaagcgg 600

 cattagcaga gattcccgga gtcaggagtg ttgtattatt tggagtagaa 650

 actcatgtgt gcatccaaca aactgccctg gagctagttg gccgaggagt 700

 cgaggttcac attgttgctg atgccacctc atcaagaagc atgatggaca 750

 ggatgtttgc acgcctcacg tctcgctcga acggggatca tagtgaccac 800

 gagtgaggct gttctgcgtt cagctggtag ctgataagga cgcatcgcaa 850

 aattcaagga aattcagaat ctaattaagg acgagtgctc cagagtcggg 900

 tctgctttcc aaagtatagg acatttgaag aactggtatg ctactcactg 950

 gtgaaggaca gtcaggtgaa ggactgtaag cccacacaag ctcttcttat 1000

 ctctactaga attaaaatgt taagtcaaaa acggctcctt ttttgcgcct 1050

 cctagtgaaa cttaaccagc tagaccattt gagtaccagc atttagttac 1100

 aaacgtcaaa ggcttccggt gctgcttacc ttcctttttt gttaatgtgc 1150

 ttttatttat taaaaaaaat tacaatgaag atgcctgttt tgtctctact 1200

 gtgtactctg atcgtatctt tccaaagtgc agactcttgt gaagttttct 1250

 taaattgttc actttaaaga aaatgacgta ccaacaatga tttggctttt 1300

 atattactgt aagatgttat aatgttaatg tggatgtagt gcttttactt 1350

 tacagattga ttggaataag attattgcat atgaatttac ccacaggact 1400

 ctgaatcatg ttacccactc ccctcacaat gttgtccact tagtgagttg 1450

 cattgatcta tccgtaccaa atgatgttga ataattacat atctttcttg 1500

 actatactga tttcttattt tggtcactat tactaaatct ctgttaatat 1550

 tctctctttt aactgaaaag ggatgggata gaagggtttg caatgccata 1600

 ttattggtgg agggctgttt taacatcttt gaagtatggc ttgctgaata 1650

 tctttaccaa catcttgaat atatattcta gtgtccacaa gatttagcaa 1700

 aaagataaag cttgggtgga atatcatttt aaaatgttca tgttctgttc 1750

 tatattttct tcacctactc tccaaatatt gtaatgcaaa aagtctcagt 1800

 aatgatttgg tagtattaat tttgtggtca ttgtttctct tcgataaatt 1850

 tattttcatt aaatacttgt tagagggttt tgaaatgttt ttcaaatatg 1900

 tgaaatgtga aactgctgtc ttttatatta aagtaattaa agaaaatgta 1950

 ttgtgattga aattattttg gcctccacaa gatggctcta tgagtattct 2000

 tccagggatt ctaatattta tttaaggtaa taaaatcttg acatttataa 2050

 tctttc 2056

<210> 3174
<211> 199
<212> PRT
<213> Homo sapien

<400> 3174
 Met His Arg Lys Phe Val Val Gln Leu Phe Ala Glu Glu Trp Gly
   1               5                  10                  15

 Gln Tyr Val Asp Leu Pro Lys Gly Phe Ala Val Ser Glu Arg Cys
                  20                  25                  30

 Lys Val Arg Leu Val Pro Leu Gln Ile Gln Leu Thr Thr Leu Gly
                  35                  40                  45

 Asn Leu Thr Pro Ser Ser Thr Val Phe Phe Cys Cys Asp Met Gln
                  50                  55                  60

 Glu Arg Phe Arg Pro Ala Ile Lys Tyr Phe Gly Asp Ile Ile Ser
                  65                  70                  75

 Val Gly Gln Arg Leu Leu Gln Gly Ala Arg Ile Leu Gly Ile Pro
                  80                  85                  90

 Val Ile Val Thr Glu Gln Tyr Pro Lys Gly Leu Gly Ser Thr Val
                  95                 100                 105

 Gln Glu Ile Asp Leu Thr Gly Val Lys Leu Val Leu Pro Lys Thr
                 110                 115                 120

 Lys Phe Ser Met Val Leu Pro Glu Val Glu Ala Ala Leu Ala Glu
                 125                 130                 135

 Ile Pro Gly Val Arg Ser Val Val Leu Phe Gly Val Glu Thr His
                 140                 145                 150

 Val Cys Ile Gln Gln Thr Ala Leu Glu Leu Val Gly Arg Gly Val
                 155                 160                 165

 Glu Val His Ile Val Ala Asp Ala Thr Ser Ser Arg Ser Met Met
                 170                 175                 180

 Asp Arg Met Phe Ala Arg Leu Thr Ser Arg Ser Asn Gly Asp His
                 185                 190                 195

 Ser Asp His Glu


<210> 3175
<211> 1032
<212> DNA
<213> Homo sapien

<400> 3175
 gttatttatt gacttttgcc aaggcttggt cacaacaatc atattcacgt 50

 aattttcccc ctttggtggc agaactgtag caataggggg agaagacaag 100

 cagcggatga agcgttttct cagcttttgg aattgcttcg acctgacatc 150

 cgttgtaacc gtttgccact tcttcagata tttttataaa aaagtaccac 200

 tgagtcagtg agggccacag attggtatta atgagatacg agggttgttg 250

 ctgggtgttt gtttcctgag ctaagtgatc aagactgtag tggagttgca 300

 gctaacatgg gttaggttta aaccgtgggg gatgcaaccc ctttgcgttt 350

 catatgtagg cctactggct ttgtgtagct ggagtagttg ggttgctttg 400

 tgttaggagg atccagatca tgttggctac agggagatgc tctctttgag 450

 aggctcctgg gcattgattc catttcaatc tcattctgga tatgtgttca 500

 ttgagtaaag gaggagagac cctcatacgc tatttaaatg tcactttttt 550

 gcctatgccc cgttttttgg tcatgtttca attaattgtg aggaaggcgc 600

 agctcctctc tgcacgtaga tcatttttta aagctaatgt aagcacatct 650

 aagggaataa catgatttaa ggttgaaatg gctttagaat catttgggtt 700

 tgagggtgtg ttattttgag tcatgaatgt acaagctctg tgaatcagac 750

 cagcttaaat acccacacct ttttttcgta ggtgggcttt tcctatcaga 800

 gcttggctca taaccaaata aagttttttg aaggccatgg cttttcacac 850

 agttatttta ttttatgacg ttatctgaaa gcagactgtt aggagcagta 900

 ttgagtggct gtcacacttt gaggcaacta aaaaggcttc aaacgttttg 950

 atcagtttct tttcaggaaa cattgtgctc taacagtatg actattcttt 1000

 cccccactct taaacagtgt gatgtgtgtt at 1032

<210> 3176
<211> 57
<212> PRT
<213> Homo sapien

<400> 3176
 Met Cys Ser Leu Ser Lys Gly Gly Glu Thr Leu Ile Arg Tyr Leu
   1               5                  10                  15

 Asn Val Thr Phe Leu Pro Met Pro Arg Phe Leu Val Met Phe Gln
                  20                  25                  30

 Leu Ile Val Arg Lys Ala Gln Leu Leu Ser Ala Arg Arg Ser Phe
                  35                  40                  45

 Phe Lys Ala Asn Val Ser Thr Ser Lys Gly Ile Thr
                  50                  55

<210> 3177
<211> 11127
<212> DNA
<213> Homo sapien

<400> 3177
 gaaattttaa tttattattc cccccttttt ttcctgcatc tataggataa 50

 tattgtaaaa tagcaattga aaccaataat cattaaataa atatcaagga 100

 aaatccaagc aaagctttct ttttgttgga ctagtggtgt ggtgtttgga 150

 gacagtctct gaatgtgaac aggaaagcac ccatcagcaa aacacgatca 200

 ctctctaggg agacagctgg gggaatctga ctctggcttc tgcttttgtt 250

 ttaagggatt aacttccctg tcaagtccaa gaagacttgc gtatgagaag 300

 attacctgat ggacttaatt ctaagattag cttttttcat caagatggaa 350

 aaagatcttt aggagcagaa aaggggagtg ctaactgggg gagcgagaag 400

 ggagacgagc aaaagaaaca aaatcttgcc acgtggctct gttttgtcag 450

 caagaggatt taagactcac ccagggcaaa cactgggacc actgtaagag 500

 cgctggaaca ttctgcctct tgagtgaagg ggccttcttt ctagcctcta 550

 tggcactgag gggtgcgccg gctggtggag gagtagtccg atggagccct 600

 gcgttccccg gggacacagg gccaagcttt gaggtggaaa gtttctggtt 650

 ctgaaacaac aaggagagag tctgtttttc ttcctaaaat ttggactctt 700

 gtctgcacaa actctggtct gttttgcacg gtttgtgtgc ctttttttcc 750

 ctttatgcaa tctttttcag ctttagcagc agaaatttgt ctagttcagg 800

 aaacatgcta gagggtggct tcagaaggaa gatgatcctg tgtattctgt 850

 ctctgcatcc gaacttttga agagaaaaat tcgagctaga gggattctta 900

 aagccttaag ttacttgaaa tctatgtatt tgcaaccctt tgtctctgga 950

 atcatattac actaaactgg aatctcaggc tgaatgagaa taaccaagtg 1000

 gagtaaaaag aagaaaaccg tttcttgatc accacttaat taacgatgct 1050

 ctttctccaa aggatcagca cgttcttcct ctgagaactt gaaaatacaa 1100

 atggacccca tgttttttta agcattacct tttcttagaa gactgccatc 1150

 atcttttata gaggaatttt ttcactatgc attcagtgga tctttataaa 1200

 atactgacct tctaattaga ttcaggtcag tcttaattaa agggggaaaa 1250

 aagcaacgca agccaaccac aaaaacacat ataccaatga aagaaattgg 1300

 tttaaatttc acagcattaa cattactttt taagtaaaac agttcattga 1350

 agaaagtatg tatgcagcag tggaacatgg gcctgtgctt tgcagtgact 1400

 ccaacatcct gtgcctgtcc tggaaggggc gtgtccccaa gagtgagaag 1450

 gagaagcctg tgtgcaggag acgctactat gaggaaggct ggctggccac 1500

 gggcaacggg cgaggagtgg ttggggtgac tttcacctct agtcactgtc 1550

 gcagggacag gagtactcca cagaggataa atttcaacct ccggggccac 1600

 aatagcgagg ttgtgctggt gaggtggaat gagccctacc agaaactggc 1650

 cacgtgcgat gcggacggag gcatattcgt gtggattcag tacgagggca 1700

 ggtggtctgt ggagctggtc aacgaccgcg gggcgcaggt gagtgatttc 1750

 acgtggagcc atgatggaac tcaagcactt atttcctatc gagatgggtt 1800

 tgtcctggtt gggtctgtca gtggacaaag acactggtca tccgaaatca 1850

 acttggaaag tcaaattacg tgtggcatat ggactcctga cgaccaacag 1900

 gtgctgtttg gcacggccga tgggcaggtg attgtcatgg attgccacgg 1950

 cagaatgctg gcccacgtcc tcttgcacga gtcagacggt gtcctcggca 2000

 tgtcctggaa ctacccgatc ttcctggtgg aggacagcag cgagagcgac 2050

 acggactcag atgactacgc ccctccccaa gatggtccgg cagcatatcc 2100

 catcccagtg cagaacatca agcctctgct caccgtcagc ttcacctcgg 2150

 gagacatcag cttaatgaac aactacgatg acttgtctcc cacggtcatc 2200

 cgctcagggc tgaaagaggt ggtagcccag tggtgcacac agggggactt 2250

 gctggcagtc gctgggatgg aacggcagac ccagcttggt gagcttccca 2300

 atggtcccct tctgaagagt gccatggtca agttctacaa tgttcgtggg 2350

 gagcacatct tcacactgga cactctcgtg cagcgcccca tcatctccat 2400

 ctgctggggt caccgggatt cgaggctgtt gatggcatca ggaccagccc 2450

 tgtacgtggt gcgtgtggag caccgggtgt ccagcctgca gctgctgtgc 2500

 cagcaggcca tcgccagcac cttgcgtgag gacaaggacg tcagcaagct 2550

 gactctgccc ccccgcctct gctcctacct ctccactgcc ttcatcccca 2600

 ccatcaagcc cccaattcca gatccgaaca acatgagaga ctttgtcagc 2650

 tacccatcag ccggcaacga gcggctgcac tgcaccatga agcgcacaga 2700

 ggacgacccg gaggtgggcg gcccgtgcta cacgctctac ctggagtacc 2750

 tgggcgggct tgtgcccatc ctcaaagggc ggcgcatcag caagctgcgg 2800

 ccagagttcg tcatcatgga cccgcggaca gatagcaaac cagatgaaat 2850

 ctatgggaac agcttgattt ctactgtgat cgacagctgc aactgctcag 2900

 actccagtga cattgagctg agtgatgact gggctgccaa gaaatctccc 2950

 aaaatctcca gagctagcaa atcacccaaa ctcccaagga tcagcattga 3000

 ggcccgcaag tcacccaagc tgccccgggc tgctcaggag ctctcccggt 3050

 ccccacggtt gcccctgcgc aagccctctg tgggctcgcc cagcctgact 3100

 cggagagagt ttccttttga agacatcact cagcacaact atcttgctca 3150

 ggtcacgtct aatatctggg gaaccaaatt taagattgtg ggcttggctg 3200

 ctttcctgcc aaccaacctc ggtgcagtaa tctataaaac cagcctcctg 3250

 catctccagc cgcggcagat gaccatttat ctcccagaag ttcggaaaat 3300

 ttccatggac tatattaatt tacctgtctt caacccaaat gttttcagtg 3350

 aagatgaaga tgatttacca gtgacaggag catctggtgt ccctgagaac 3400

 agcccacctt gtaccgtgaa catccctatt gcaccgatcc acagctcggc 3450

 tcaggctatg tcccccacgc agagcatagg gctggtgcag tccctactgg 3500

 ccaatcagaa tgtgcagcta gatgtcctga ccaaccagac gacagctgta 3550

 gggacagcag aacatgcagg tgacaggtgc cacccagtaa cccaggtctc 3600

 caaccggtac tccaatcctg gacaggtgat tttcggaagc gtggaaatgg 3650

 gccgcatcat tcagaacccc cctccactgt ccctgcctcc cccgccgcag 3700

 gggcccatgc agctgtccac ggtgggccat ggagaccgag accacgaaca 3750

 cctgcagaag tcagccaagg ccctgcggcc aacaccgcag ctggcagctg 3800

 agggggacgc agtggtcttt agtgcccccc aggaggtcca ggtgacgaag 3850

 ataaaccctc cacccccgta cccaggaacc atccccgctg cccccaccac 3900

 agcagcaccc ccgccccctc tgccgccccc acagccccca gtggatgtgt 3950

 gcttgaagaa gggcgacttc tccctctacc ccacgtcagt gcactaccag 4000

 acccccctgg gctatgagag gatcaccacc ttcgacagca gtggcaacgt 4050

 ggaggaggtg tgccggcccc gcacccggat gctgtgctcc cagaacacct 4100

 acaccctccc cggcccgggt agctctgcca ccttgaggct cacggccact 4150

 gagaagaagg tccctcagcc ctgcagcagt gccaccctga accgcctgac 4200

 cgtccctcgc tactccatcc ccaccgggga cccacccccg tatcctgaaa 4250

 ttgccagcca gctggcccag gggcgggggg ctgcccagag gtccgacaat 4300

 agcctcatcc acgctaccct gcggaggaac aaccgtgagg ctacgctcaa 4350

 gatggcccag ctggccgaca gcccgcgggc ccccctgcag cccctggcca 4400

 agtccaaggg cgggcccggg ggggtggtga cacagctccc agcgcggccc 4450

 ccacctgccc tgtacacctg cagtcagtgc agtggcacag ggcccagctc 4500

 acagcccgga gcctccctgg cccataccgc cagcgcctcc ccgttggcct 4550

 cccagtcctc ctacagcctc ctgagcccac ccgacagcgc ccgcgaccgc 4600

 accgactacg tcaactcggc cttcacggag gacgaggccc tgtcccagca 4650

 ctgtcagctt gagaagccct tgaggcaccc tcccctgcct gaagctgctg 4700

 tcaccctgaa acggccaccc ccttaccagt gggaccccat gctgggtgag 4750

 gacgtttggg ttcctcaaga aaggacagca cagacttcag ggcccaaccc 4800

 cttaaaactg tcctctctga tgctgagtca gggccagcac ctggacgtgt 4850

 cccgactgcc cttcatctcc cccaagtctc ctgccagccc cactgccact 4900

 ttccaaacag gctatgggat gggagtgcca tatccaggaa gctataacaa 4950

 cccccctttg cctggagtgc aggctccctg ctctcccaaa gatgccctgt 5000

 ccccaacgca gtttgcacaa caggagcctg ctgtggtcct tcagccgctg 5050

 tacccaccca gcctctccta ttgcaccctg ccccccatgt acccaggaag 5100

 cagcacgtgc tctagtttac agctgccacc tgtcgccttg catccatgga 5150

 gttcctacag cgcctgcccg cccatgcaga acccccaggg cactctcccc 5200

 ccaaagccac acttggtggt ggagaagccc cttgtgtccc caccacctgc 5250

 cgacctccaa agccacttgg gcacagaggt gatggtagag actgcagaca 5300

 acttccagga agtcctctcc ctgaccgaaa gcccagtccc ccagcggaca 5350

 gaaaaatttg gaaagaagaa ccggaagcgc ctggacagcc gagcagaaga 5400

 aggcagcgtt caggccatca ctgagggcaa agtgaagaag gaggctagga 5450

 ctttgagtga ctttaattcc ctaatctcca gcccacacct ggggagagag 5500

 aagaagaaag tgaagagtca gaaagaccaa ctgaagtcaa agaagttgaa 5550

 taagacaaac gagttccagg acagctccga gagcgagcct gagctgttca 5600

 tcagcgggga tgagctcatg aaccagagcc agggcagcag aaagggctgg 5650

 aaaagcaagc gctccccacg ggccgccggc gagctggagg aggccaagtg 5700

 ccggcgggcc agtgagaagg aggacgggcg gctgggcagc caaggcttcg 5750

 tgtacgtgat ggccaacaag cagccgctgt ggaacgaggc cacccaggtc 5800

 taccagctgg acttcggggg gcgggtgacc caggagtccg ccaagaactt 5850

 ccagattgag ttagaggggc ggcaggtgat gcagtttgga cggattgatg 5900

 gcagtgcgta cattctagac ttccagtatc cgttctcagc cgtgcaggcc 5950

 tttgcagttg ccctggccaa cgtgactcag cgcctcaaat gaagagactg 6000

 gtgtggggag gagagagatg cagagagcct ttggaagagg tcttcggaga 6050

 tgccagagga gccctctagg ggtccgatgc ctgggaggac cagaagccaa 6100

 cagcaaaact ggaaaagccc ggcaggccca ggagagggcg ctgacctgtg 6150

 gtcgtcattt atttggttgg gttttattac cttttattgt ctgttcttct 6200

 tttcttcttt catttcagtg gcatttggaa gcaaagagtg ctaggcacct 6250

 gcagttcttt caggaaacag cttggctgtg gtaatgctct actgggccct 6300

 tcagaatgaa gacagtctgc cttagagcct gctattcttt tagacatagg 6350

 gaggatgcat tatcctgtat tctcctccaa catcaccact agcgtaaaag 6400

 caaaaagctt ttacaaaaca cagccaaaaa ttctcaagat gcaggttctt 6450

 ggggaatggg atggggacag catttgattt acactgatta tgttactccc 6500

 caaaaggtga cttaattaat aaagggcatt tgggcagaca cactgtgttg 6550

 gaccaacaaa gtaggctctt tacaggggtg ttctcaccag gtagaaatgc 6600

 gatttgctca ctgaggatgt tggggaaggg acgaagggta aagaagaaac 6650

 tgcaccgtat acacaggttc acatcactct gcagacagca atgtgactca 6700

 gcgtgtgact tgtagcagca gtacgagggc tacactcctc tgctgaggat 6750

 gtctacattg aaagcctcca ctagtttcat cgtttgtcaa gttccgtaga 6800

 tcagtgatgg tcattcagca tgactggttc tgggagaagg tgagagacaa 6850

 aaatggaaag atcctggcct gtggtagtgg tagcagtttt ctcaaataat 6900

 gtggtgacag tcactagatc ctcacatgct gagaaacagc ctctactctc 6950

 tctgcccctt ttacttttta atctggaatg cattactgta aacatgatct 7000

 ttcccatgag ataccatgtt ctatgccttc ccattctaaa agtgtggaca 7050

 acgcttgatt tgaaaccact ccttttctcc tcttggctac attaaaattc 7100

 agttgactac aaatgctttc tatcaaatta gaaatgtaac caaaaaaatg 7150

 ttaagtgttc accagggtat taaaatacag agggagtatg gtcaaatctt 7200

 ttgacaaaat tttcatgatc ttctctaaca aaaaaagttg tttattaact 7250

 gtacagactg tttactaagg agctaaacca ctgagaaaac gttattaaaa 7300

 ttgtaatacc taggtagttg gttgatcaca gtttgttaat tgtataaaaa 7350

 aaaattacct agaatatctc ttcccacttc ctcgtcctcg tgagaacctg 7400

 tgggcagtat tcaagccctg atgacaaaac ccagtgtttt ttgttgttgt 7450

 tttttgttgt tgttttttgt ttttgttttt gtttttctca gtcttacctg 7500

 tgatgttgtt taggatcagg cccctctcct gggcctgctg tgcaggagca 7550

 caggaactat ctgctggcgt tgggttccaa atttgcattt tatttggaaa 7600

 cagacaagta gaagatgcta cagaaaagta ttttcaaatt taaacgtttt 7650

 ttaatcccct gttttagtta aaaaattgga aaagaaaccg acccattttt 7700

 ttcccagatc aagatgacat gacatcactc ccaattctct ccaaacccca 7750

 gagaaatact gacgaagttt tctgatgtgg caaaggatat ttcccatcta 7800

 ataccagttt ctcatttata tttaacgtat tggacctgat atttttagtg 7850

 ggtgcattct tccagaaaga attcagcaat gttatcagaa ttaattcttt 7900

 tatatgagtt tatgtagctt gatatggtgt ttcagtgctt attggttgtg 7950

 caataatggt tatagcctgt tagataatct aaatgcaatt cccctgtttt 8000

 gtcgtttagg agataattat ttatcttgct tttcatagtg ttcttaggaa 8050

 ttattttgtt gttacgtttt ggtgagttat acccatttta tttatttaga 8100

 aaaatagtat ctttgttaac gacttacatg gtcacagtat attttgctgc 8150

 aagaaataaa gaggatatga tagaaggttt tttttttttt tttttttttt 8200

 ttttgagacg gagtcccact cttgtcgccc aactagagtg tagtggcaca 8250

 atctcggctc cccacaacct ctgactccag ggttcaggtg attattttgc 8300

 ctcagcctcc caagcagctg ggattataga cacccgccaa cacgccaggc 8350

 taatgttttt gtatttttaa tagagatggg gttttgccat gttggccagg 8400

 ctggtcttga actcctgacc tcaggtgatc cgcccgcctc ggcctcccaa 8450

 agtgctggga ttacagacgt gagccaccac tcccggccca tagaaggttt 8500

 tttgctggat aatttgtaac ttttctaatt gggaaaaaat tcctattaat 8550

 cacttaaaaa tttttttttg tattttgtgt tattgattat atacaaagga 8600

 gacttttttt ttgagataac actcaaatag tattctcttc ttttgaaaat 8650

 tttattttta tctgaaaata acagttgatc tgaaataaaa aggggagacc 8700

 tattagaatg agagtagcca aggaaagagt tactaggtaa taagcttcac 8750

 tttttgtgtt ctaattgttt ttgagatata aagaccctga aaaagcccat 8800

 tttagaacct gtttaataag agcaaatata ggggaaaatc tttgaaatga 8850

 aagctacaaa tacatgtgag aagaaaaaaa tggatttttt tagcaaataa 8900

 ttaactaagc ttctaaatgc ctagctccct cccccaaagg cgctttcccc 8950

 cgatggaggc acaggcttct gtctcggatg tttggcgcac gtgagtttgt 9000

 atgagtttgt accggagtga ccccggcagc cactgcccac ctcccctcta 9050

 cccaggggcc tgaaaagagg ggctgccctc ctgcgccaag gcagacacaa 9100

 gctgcgggct gtgcggtcct agtagtgtga cgtttcagtt aatagtggtg 9150

 gtcttatttt caactatgct ttcattcagt cagtctctgt tgactaaata 9200

 cgacgaaaat tcatacttta tgcaggagat ttctaaaaat ttaatgttta 9250

 ttaatagttt atgaatatca agatacctca ttgaatccct aaatttaaaa 9300

 gcagtccagt aaaaggttaa ctgtataaag aatctatgac tttttgaggg 9350

 aagtgtgata tattaacaaa tataaccaat tctaaatttg ttttagctct 9400

 aacctcatca aaccaaaggc acagatttgt gtacaatata cccattgaat 9450

 gtatatcctg agaaaaattg gggccaaaga agcaggaaaa tctcaaagct 9500

 ctaatggcag cataaatcaa agaatttcac aggctagtgt ttttatccat 9550

 agccattgct cccttgtcaa gtgtctcaca aggacatgga agaatgtgtt 9600

 atgttcatct tgtaatcata gcaaaaagtc tgcaaacccc agggtcaagc 9650

 ctgctctgcc acagggttgg atggtgacct tgggcaagtc cctggggctg 9700

 gctaggcctc cacttgtcca tctgtgaaat gaaaggatca gcctggacag 9750

 ccctctaaac tcccttacag ctctcagcct aagagcgcag cactgaacag 9800

 cctcatcatt ccacttttca tgggaaatat atttcacacc attgcctttg 9850

 tgtagagaaa tatttctttt cctgtgttaa tgagctatgt actgaatata 9900

 aaccagtgca tttaaagtaa tatcttttgt gcacctctaa atgtgtttgg 9950

 aattgtgttt gttctcatag aatatacaaa agtactgatt ctaggtaaga 10000

 aggagtctcc acgggtgtgc cctgctcagc tggatgtcca tgagaacagc 10050

 catgaaataa gtcactactt gtccccaaaa ccacaggaat atatacctag 10100

 gtcacctcaa attcctgagt gtgctctgcc atgttacacg gtcttcaaat 10150

 tgaaaaggtt tcttgaaaag gaaagtttgg cccagcaact ggagaaggag 10200

 tccatggtgt cgctgtgtgc ctgtatcatt tggccaagtc aatggttgta 10250

 agcaaagtta gtggagacaa aaatgtgtcc aaaatgtcgt ttgagttcct 10300

 gggatttctg taatagcaca caactcagaa ctcttcagca tttgtgtgat 10350

 tccttacctc tggctgataa aactctaatg ggttgtggct tactttgttt 10400

 ccattttctt tggctttgtg caatttttgt gtaactttac ttgtacctat 10450

 attttctgtt tacagttctt tttaagggga ggggtagggt tctaagatct 10500

 tgttgtttat tgtagataaa aattttttcg tgttgtagaa aagcatgggt 10550

 tatgcgtttg actgaaaaag acactgtatt atttaccaaa ggggtattgt 10600

 ttttgcattt gtttataaat gcattatttt ggtactgtaa atttggacat 10650

 aatttctgag tttattacta ctggcatttt ctttttccct tttttttttt 10700

 tttaaccgta agtgcacgat gcaggtgcat aggccccaga ccaaactaga 10750

 ccaccagcat gttcatgtcc agacctcggc agtggcgtgc actgcttgtg 10800

 cacctcagtt cctccagtgt tggtttgttt gttttttaat tcagcatcct 10850

 gctggtttta ctttccaagc aagatctgtt gcgactccca aatgcgtttt 10900

 aatgagctca tccttatttg cctttcttct tacgtatttt gtgtattaga 10950

 ttgtgcagga gatattctag aaggcattaa tggtttgcat tcaaaacgat 11000

 gtggtttgtc caagttattt tctgtcttta ttactgagac ggattaatct 11050

 ccttattttt ttcttgatga tttgaagttg taagagttgt ccagctattg 11100

 cttaataaaa ttttgcagat caaaaaa 11127

<210> 3178
<211> 1544
<212> PRT
<213> Homo sapien

<400> 3178
 Met Tyr Ala Ala Val Glu His Gly Pro Val Leu Cys Ser Asp Ser
   1               5                  10                  15

 Asn Ile Leu Cys Leu Ser Trp Lys Gly Arg Val Pro Lys Ser Glu
                  20                  25                  30

 Lys Glu Lys Pro Val Cys Arg Arg Arg Tyr Tyr Glu Glu Gly Trp
                  35                  40                  45

 Leu Ala Thr Gly Asn Gly Arg Gly Val Val Gly Val Thr Phe Thr
                  50                  55                  60

 Ser Ser His Cys Arg Arg Asp Arg Ser Thr Pro Gln Arg Ile Asn
                  65                  70                  75

 Phe Asn Leu Arg Gly His Asn Ser Glu Val Val Leu Val Arg Trp
                  80                  85                  90

 Asn Glu Pro Tyr Gln Lys Leu Ala Thr Cys Asp Ala Asp Gly Gly
                  95                 100                 105

 Ile Phe Val Trp Ile Gln Tyr Glu Gly Arg Trp Ser Val Glu Leu
                 110                 115                 120

 Val Asn Asp Arg Gly Ala Gln Val Ser Asp Phe Thr Trp Ser His
                 125                 130                 135

 Asp Gly Thr Gln Ala Leu Ile Ser Tyr Arg Asp Gly Phe Val Leu
                 140                 145                 150

 Val Gly Ser Val Ser Gly Gln Arg His Trp Ser Ser Glu Ile Asn
                 155                 160                 165

 Leu Glu Ser Gln Ile Thr Cys Gly Ile Trp Thr Pro Asp Asp Gln
                 170                 175                 180

 Gln Val Leu Phe Gly Thr Ala Asp Gly Gln Val Ile Val Met Asp
                 185                 190                 195

 Cys His Gly Arg Met Leu Ala His Val Leu Leu His Glu Ser Asp
                 200                 205                 210

 Gly Val Leu Gly Met Ser Trp Asn Tyr Pro Ile Phe Leu Val Glu
                 215                 220                 225

 Asp Ser Ser Glu Ser Asp Thr Asp Ser Asp Asp Tyr Ala Pro Pro
                 230                 235                 240

 Gln Asp Gly Pro Ala Ala Tyr Pro Ile Pro Val Gln Asn Ile Lys
                 245                 250                 255

 Pro Leu Leu Thr Val Ser Phe Thr Ser Gly Asp Ile Ser Leu Met
                 260                 265                 270

 Asn Asn Tyr Asp Asp Leu Ser Pro Thr Val Ile Arg Ser Gly Leu
                 275                 280                 285

 Lys Glu Val Val Ala Gln Trp Cys Thr Gln Gly Asp Leu Leu Ala
                 290                 295                 300

 Val Ala Gly Met Glu Arg Gln Thr Gln Leu Gly Glu Leu Pro Asn
                 305                 310                 315

 Gly Pro Leu Leu Lys Ser Ala Met Val Lys Phe Tyr Asn Val Arg
                 320                 325                 330

 Gly Glu His Ile Phe Thr Leu Asp Thr Leu Val Gln Arg Pro Ile
                 335                 340                 345

 Ile Ser Ile Cys Trp Gly His Arg Asp Ser Arg Leu Leu Met Ala
                 350                 355                 360

 Ser Gly Pro Ala Leu Tyr Val Val Arg Val Glu His Arg Val Ser
                 365                 370                 375

 Ser Leu Gln Leu Leu Cys Gln Gln Ala Ile Ala Ser Thr Leu Arg
                 380                 385                 390

 Glu Asp Lys Asp Val Ser Lys Leu Thr Leu Pro Pro Arg Leu Cys
                 395                 400                 405

 Ser Tyr Leu Ser Thr Ala Phe Ile Pro Thr Ile Lys Pro Pro Ile
                 410                 415                 420

 Pro Asp Pro Asn Asn Met Arg Asp Phe Val Ser Tyr Pro Ser Ala
                 425                 430                 435

 Gly Asn Glu Arg Leu His Cys Thr Met Lys Arg Thr Glu Asp Asp
                 440                 445                 450

 Pro Glu Val Gly Gly Pro Cys Tyr Thr Leu Tyr Leu Glu Tyr Leu
                 455                 460                 465

 Gly Gly Leu Val Pro Ile Leu Lys Gly Arg Arg Ile Ser Lys Leu
                 470                 475                 480

 Arg Pro Glu Phe Val Ile Met Asp Pro Arg Thr Asp Ser Lys Pro
                 485                 490                 495

 Asp Glu Ile Tyr Gly Asn Ser Leu Ile Ser Thr Val Ile Asp Ser
                 500                 505                 510

 Cys Asn Cys Ser Asp Ser Ser Asp Ile Glu Leu Ser Asp Asp Trp
                 515                 520                 525

 Ala Ala Lys Lys Ser Pro Lys Ile Ser Arg Ala Ser Lys Ser Pro
                 530                 535                 540

 Lys Leu Pro Arg Ile Ser Ile Glu Ala Arg Lys Ser Pro Lys Leu
                 545                 550                 555

 Pro Arg Ala Ala Gln Glu Leu Ser Arg Ser Pro Arg Leu Pro Leu
                 560                 565                 570

 Arg Lys Pro Ser Val Gly Ser Pro Ser Leu Thr Arg Arg Glu Phe
                 575                 580                 585

 Pro Phe Glu Asp Ile Thr Gln His Asn Tyr Leu Ala Gln Val Thr
                 590                 595                 600

 Ser Asn Ile Trp Gly Thr Lys Phe Lys Ile Val Gly Leu Ala Ala
                 605                 610                 615

 Phe Leu Pro Thr Asn Leu Gly Ala Val Ile Tyr Lys Thr Ser Leu
                 620                 625                 630

 Leu His Leu Gln Pro Arg Gln Met Thr Ile Tyr Leu Pro Glu Val
                 635                 640                 645

 Arg Lys Ile Ser Met Asp Tyr Ile Asn Leu Pro Val Phe Asn Pro
                 650                 655                 660

 Asn Val Phe Ser Glu Asp Glu Asp Asp Leu Pro Val Thr Gly Ala
                 665                 670                 675

 Ser Gly Val Pro Glu Asn Ser Pro Pro Cys Thr Val Asn Ile Pro
                 680                 685                 690

 Ile Ala Pro Ile His Ser Ser Ala Gln Ala Met Ser Pro Thr Gln
                 695                 700                 705

 Ser Ile Gly Leu Val Gln Ser Leu Leu Ala Asn Gln Asn Val Gln
                 710                 715                 720

 Leu Asp Val Leu Thr Asn Gln Thr Thr Ala Val Gly Thr Ala Glu
                 725                 730                 735

 His Ala Gly Asp Arg Cys His Pro Val Thr Gln Val Ser Asn Arg
                 740                 745                 750

 Tyr Ser Asn Pro Gly Gln Val Ile Phe Gly Ser Val Glu Met Gly
                 755                 760                 765

 Arg Ile Ile Gln Asn Pro Pro Pro Leu Ser Leu Pro Pro Pro Pro
                 770                 775                 780

 Gln Gly Pro Met Gln Leu Ser Thr Val Gly His Gly Asp Arg Asp
                 785                 790                 795

 His Glu His Leu Gln Lys Ser Ala Lys Ala Leu Arg Pro Thr Pro
                 800                 805                 810

 Gln Leu Ala Ala Glu Gly Asp Ala Val Val Phe Ser Ala Pro Gln
                 815                 820                 825

 Glu Val Gln Val Thr Lys Ile Asn Pro Pro Pro Pro Tyr Pro Gly
                 830                 835                 840

 Thr Ile Pro Ala Ala Pro Thr Thr Ala Ala Pro Pro Pro Pro Leu
                 845                 850                 855

 Pro Pro Pro Gln Pro Pro Val Asp Val Cys Leu Lys Lys Gly Asp
                 860                 865                 870

 Phe Ser Leu Tyr Pro Thr Ser Val His Tyr Gln Thr Pro Leu Gly
                 875                 880                 885

 Tyr Glu Arg Ile Thr Thr Phe Asp Ser Ser Gly Asn Val Glu Glu
                 890                 895                 900

 Val Cys Arg Pro Arg Thr Arg Met Leu Cys Ser Gln Asn Thr Tyr
                 905                 910                 915

 Thr Leu Pro Gly Pro Gly Ser Ser Ala Thr Leu Arg Leu Thr Ala
                 920                 925                 930

 Thr Glu Lys Lys Val Pro Gln Pro Cys Ser Ser Ala Thr Leu Asn
                 935                 940                 945

 Arg Leu Thr Val Pro Arg Tyr Ser Ile Pro Thr Gly Asp Pro Pro
                 950                 955                 960

 Pro Tyr Pro Glu Ile Ala Ser Gln Leu Ala Gln Gly Arg Gly Ala
                 965                 970                 975

 Ala Gln Arg Ser Asp Asn Ser Leu Ile His Ala Thr Leu Arg Arg
                 980                 985                 990

 Asn Asn Arg Glu Ala Thr Leu Lys Met Ala Gln Leu Ala Asp Ser
                 995                1000                1005

 Pro Arg Ala Pro Leu Gln Pro Leu Ala Lys Ser Lys Gly Gly Pro
                1010                1015                1020

 Gly Gly Val Val Thr Gln Leu Pro Ala Arg Pro Pro Pro Ala Leu
                1025                1030                1035

 Tyr Thr Cys Ser Gln Cys Ser Gly Thr Gly Pro Ser Ser Gln Pro
                1040                1045                1050

 Gly Ala Ser Leu Ala His Thr Ala Ser Ala Ser Pro Leu Ala Ser
                1055                1060                1065

 Gln Ser Ser Tyr Ser Leu Leu Ser Pro Pro Asp Ser Ala Arg Asp
                1070                1075                1080

 Arg Thr Asp Tyr Val Asn Ser Ala Phe Thr Glu Asp Glu Ala Leu
                1085                1090                1095

 Ser Gln His Cys Gln Leu Glu Lys Pro Leu Arg His Pro Pro Leu
                1100                1105                1110

 Pro Glu Ala Ala Val Thr Leu Lys Arg Pro Pro Pro Tyr Gln Trp
                1115                1120                1125

 Asp Pro Met Leu Gly Glu Asp Val Trp Val Pro Gln Glu Arg Thr
                1130                1135                1140

 Ala Gln Thr Ser Gly Pro Asn Pro Leu Lys Leu Ser Ser Leu Met
                1145                1150                1155

 Leu Ser Gln Gly Gln His Leu Asp Val Ser Arg Leu Pro Phe Ile
                1160                1165                1170

 Ser Pro Lys Ser Pro Ala Ser Pro Thr Ala Thr Phe Gln Thr Gly
                1175                1180                1185

 Tyr Gly Met Gly Val Pro Tyr Pro Gly Ser Tyr Asn Asn Pro Pro
                1190                1195                1200

 Leu Pro Gly Val Gln Ala Pro Cys Ser Pro Lys Asp Ala Leu Ser
                1205                1210                1215

 Pro Thr Gln Phe Ala Gln Gln Glu Pro Ala Val Val Leu Gln Pro
                1220                1225                1230

 Leu Tyr Pro Pro Ser Leu Ser Tyr Cys Thr Leu Pro Pro Met Tyr
                1235                1240                1245

 Pro Gly Ser Ser Thr Cys Ser Ser Leu Gln Leu Pro Pro Val Ala
                1250                1255                1260

 Leu His Pro Trp Ser Ser Tyr Ser Ala Cys Pro Pro Met Gln Asn
                1265                1270                1275

 Pro Gln Gly Thr Leu Pro Pro Lys Pro His Leu Val Val Glu Lys
                1280                1285                1290

 Pro Leu Val Ser Pro Pro Pro Ala Asp Leu Gln Ser His Leu Gly
                1295                1300                1305

 Thr Glu Val Met Val Glu Thr Ala Asp Asn Phe Gln Glu Val Leu
                1310                1315                1320

 Ser Leu Thr Glu Ser Pro Val Pro Gln Arg Thr Glu Lys Phe Gly
                1325                1330                1335

 Lys Lys Asn Arg Lys Arg Leu Asp Ser Arg Ala Glu Glu Gly Ser
                1340                1345                1350

 Val Gln Ala Ile Thr Glu Gly Lys Val Lys Lys Glu Ala Arg Thr
                1355                1360                1365

 Leu Ser Asp Phe Asn Ser Leu Ile Ser Ser Pro His Leu Gly Arg
                1370                1375                1380

 Glu Lys Lys Lys Val Lys Ser Gln Lys Asp Gln Leu Lys Ser Lys
                1385                1390                1395

 Lys Leu Asn Lys Thr Asn Glu Phe Gln Asp Ser Ser Glu Ser Glu
                1400                1405                1410

 Pro Glu Leu Phe Ile Ser Gly Asp Glu Leu Met Asn Gln Ser Gln
                1415                1420                1425

 Gly Ser Arg Lys Gly Trp Lys Ser Lys Arg Ser Pro Arg Ala Ala
                1430                1435                1440

 Gly Glu Leu Glu Glu Ala Lys Cys Arg Arg Ala Ser Glu Lys Glu
                1445                1450                1455

 Asp Gly Arg Leu Gly Ser Gln Gly Phe Val Tyr Val Met Ala Asn
                1460                1465                1470

 Lys Gln Pro Leu Trp Asn Glu Ala Thr Gln Val Tyr Gln Leu Asp
                1475                1480                1485

 Phe Gly Gly Arg Val Thr Gln Glu Ser Ala Lys Asn Phe Gln Ile
                1490                1495                1500

 Glu Leu Glu Gly Arg Gln Val Met Gln Phe Gly Arg Ile Asp Gly
                1505                1510                1515

 Ser Ala Tyr Ile Leu Asp Phe Gln Tyr Pro Phe Ser Ala Val Gln
                1520                1525                1530

 Ala Phe Ala Val Ala Leu Ala Asn Val Thr Gln Arg Leu Lys
                1535                1540

<210> 3179
<211> 1977
<212> DNA
<213> Homo sapien

<400> 3179
 gcccttcggg acgagctgga ggcagagcgt gagtacaaag tgatcggcct 50

 cggccgcacg tagtagcccc cctactcccc ggccaagtca gggcctccct 100

 cttcccgcgg agtcgcaacc acgggtagct cgtgtaggta acggcaggtc 150

 caggcctccg catgagcgga gggccccccg cgcgaccttg aatggcccgg 200

 gcgcgcgcgg tcgtgtggga gttgtagtcc tccgtccccg tccgcgcgga 250

 ctccgtttcc cgtggtgccc cgggcggccc gcttccggcg cagttagtta 300

 cgagtcggcg cacgcggcct cggtccggtt gactttgcgg agccatggag 350

 ggcggcttcg gctccgattt cgggggctcc ggcagcggga agctggaccc 400

 agggctcata atggagcagg tgaaagtgca gatcgccgtg gccaacgcgc 450

 aggagctgct gcagaggatg acggacaagt gtttccggaa gtgtataggg 500

 aaacctgggg gctccctgga caactccgag cagaagtgca tcgccatgtg 550

 catggaccgc tacatggacg cctggaacac cgtgtctcgc gcctacaact 600

 cgcggctgca gcgggaacga gccaacatgt gaccggcgag cgcgggccac 650

 cccaccctgt tcatttccat aaacgtgctt tgagaggcgg ggtccgcatg 700

 tacgtactgc ctgcccgggg cttaggaggg tggcaccggt gctgggacac 750

 acgggactgt gtcctcgcca ccccccgccc tgccccctgc cagccagtgc 800

 agcttggatc tcgggggtgt ggggccctgt gccttcctga agtgctggca 850

 gcccagtggc acctccttca ggcctttggg gtattcccct agtgtgccca 900

 agtcagcctc atattctggg cggacagctt gtctggactt cggagttggg 950

 ggtggtcaga caccacagga gctgtcacct cctgcggatg ggcaaataaa 1000

 ttggtggagg acggagagaa acctctttat ttccctcctg aggggtctct 1050

 gggaagaggt gacgcgtgtc cctggaaccc cagctcggag ggtctcagcc 1100

 tcccctgggt tgggagaagt ccatctttcc ccttagtgcc accgggctgc 1150

 tgagtcacga ggaatgtgtt gctgctgcca cccctgcccc aaaggctaag 1200

 ggggacagcc ttccccttgt cagggcttgc tttgaccctg cttcgttcca 1250

 ccccgggtcc tggtggagca ccaggcaggt ggtcctcgct gtgacactga 1300

 ggtgctgagc cagtgagcta gggtggaggg gctgtgttta ttggaacaaa 1350

 gggtggtacc aaaatgcatc cccatgaccc acagcccccc cacacccgtc 1400

 cttgggtagg gtacggtggg gtggggtgtt gggtggcctg ctgctcctgt 1450

 tgctttcacg tagagtctcg gcctgggcag tcacgtggtg gtcactcctg 1500

 gatgtgctgt cctatccagc ctctcacagc tgccacccgg gtatagacac 1550

 ctgggaagtg gggccggcca cagccatagc cccagctagt gaccccagtt 1600

 agcacccacc gtccagaggg ctccctgcag gccaggggtc ccccagcgtc 1650

 accctgttgg ggagagaaga aagggggttc agaggccggt acctccccta 1700

 cagcagccct tgggtcattg gcccctctag gagtgaccct agtgacttcc 1750

 cctgggagcc gcattttcac tatctggaaa atgggctcaa tgcaaaggtg 1800

 gcagacattt atggacaccc gccacgtggt cccggagtgg aacggtgcct 1850

 cccactgcag cctctgcctg ctctgccgcc gaggcccggg gatgggatgc 1900

 ggtgggttgc ccaataaacg gctgtggagt ggaaattcct ccagagccaa 1950

 aaaggcaaaa aaaaaaaaaa aaaaaaa 1977

<210> 3180
<211> 95
<212> PRT
<213> Homo sapien

<400> 3180
 Met Glu Gly Gly Phe Gly Ser Asp Phe Gly Gly Ser Gly Ser Gly
   1               5                  10                  15

 Lys Leu Asp Pro Gly Leu Ile Met Glu Gln Val Lys Val Gln Ile
                  20                  25                  30

 Ala Val Ala Asn Ala Gln Glu Leu Leu Gln Arg Met Thr Asp Lys
                  35                  40                  45

 Cys Phe Arg Lys Cys Ile Gly Lys Pro Gly Gly Ser Leu Asp Asn
                  50                  55                  60

 Ser Glu Gln Lys Cys Ile Ala Met Cys Met Asp Arg Tyr Met Asp
                  65                  70                  75

 Ala Trp Asn Thr Val Ser Arg Ala Tyr Asn Ser Arg Leu Gln Arg
                  80                  85                  90

 Glu Arg Ala Asn Met
                  95

<210> 3181
<211> 8500
<212> DNA
<213> Homo sapien

<400> 3181
 cgtcatggcc gtcagcaccg cgttcccgtc ctcttccgct tggccccaga 50

 aagtttcggt tctgcccggc ggtggaccca cgagcgcgtg ccaccatgga 100

 gtctgaccac tgctgagcag acagccaccg agggccgaaa ttctgagcct 150

 tcctctggac ccaggcagga gacatacaga caagaaaggc aaactcacca 200

 tggcctccac caatgcagag agccagctcc agagaatcat ccgagacttg 250

 caagatgctg tgacagaact aagcaaagaa tttcaggaag caggggaacc 300

 catcacggat gacagcacca gcttgcataa attttcttat aaacttgagt 350

 atctcctgca atttgatcag aaagagaagg ccaccctcct gggcaacaag 400

 aaggactact gggattactt ctgtgcctgc ctggccaagg tgaaaggagc 450

 caatgatggg atccgatttg tcaagtctat ctcagagctc cgaacatcct 500

 tggggaaagg aagagcattt attcgctact ccttggtgca ccagaggttg 550

 gcagacacct tacagcagtg cttcatgaac accaaagtga ccagtgactg 600

 gtactatgca agaagcccct ttctgcagcc aaagctgagc tcggacattg 650

 tgggccaact ctatgagctg actgaggttc agtttgacct ggcgtcgagg 700

 ggctttgact tggatgctgc ctggccaaca tttgccagga ggacgctgac 750

 cactggctct tctgcttacc tgtggaaacc ccctagccgc agctccagca 800

 tgagcagctt ggtgagcagc tacctgcaga ctcaagagat ggtgtccaac 850

 tttgacctga acagccccct aaacaacgag gcattggagg gctttgatga 900

 gatgcgacta gagctggacc agttggaggt gcgggagaag cagctacagg 950

 agcgcatgca gcagctggac agagagaacc aggagctgag ggcagctgtc 1000

 agccagcaag gggagcaact gcagacagag agggagaggg ggcgcactgc 1050

 agcggaggac aacgttcgcc tcacttgctt ggtagctgag ctccagaagc 1100

 agtgggaggt cacccaggcc acccagaaca ctgtgaagga gctgcagaca 1150

 tgcctgcagg ccctggagct aggagcagca gagaaggagg aggactacca 1200

 cacagccctg cggcggctgg agtccatgct gcagcccttg gcacaggagc 1250

 ttgaggccac acgggactca ctggacaaga aaaaccagca tttagccagc 1300

 ttcccaggct ggctagccat ggctcagcag aaggcagatt cggcatcaga 1350

 cacaaagggc cggcaagaac ctattcccag tgatgcggcc caggagatgc 1400

 aggagctagg ggagaagctt caagccctag aaagggagag aaccaaggtc 1450

 gaggaggtca acagacagca gagtgcccaa ctggaacagc tggtcaagga 1500

 gcttcagctg aaagaggatg cccgggccag cctggagcgc ctggtgaagg 1550

 agatggcccc actccaggag gagttgtctg ggaagggaca ggaggcagac 1600

 cagctctggc gacggctgca ggagttgctg gcccacacga gctcctggga 1650

 ggaggagcta gcagagttga ggcgggagaa aaaacagcaa caggaggaga 1700

 aggagctgct ggagcaggag gtcaggtctc tgacccggca gctgcagttc 1750

 ctggagaccc agctggcaca ggtgagccaa catgtgagtg acctggagga 1800

 gcagaagaag cagctcattc aggacaaaga ccacctcagc cagcaggtgg 1850

 gtatgctcga gcggcttgct gggccgcctg gcccagaact gccagtggca 1900

 ggtgagaaga atgaggccct ggtccctgtg aactccagtc tgcaagaggc 1950

 ctgggggaag ccagaggagg agcagagggg cctgcaggag gcacagttag 2000

 acgataccaa ggtgcaagag ggcagccagg aggaagagct ccggcaggcc 2050

 aacagggagc tggagaagga gctacagaat gtggtcgggc gtaaccagct 2100

 cctggagggc aagctgcaag ccctgcaggc cgattaccag gctttgcagc 2150

 agcgggaatc agccatccag ggctccttgg cctccctgga ggccgagcag 2200

 gccagcatcc ggcacttggg tgaccagatg gaggcgagct tgctggctgt 2250

 aaggaaggcc aaggaggcca tgaaagccca gatggcagag aaggaggcca 2300

 ttctacagag caaggagggc gagtgtcagc agctgcggga ggaggtggag 2350

 cagtgccagc aactggcaga agcccggcac agagagctta gggctctcga 2400

 gagccagtgc cagcagcaga cccagctgat tgaggtcctc acagcagaga 2450

 aaggccaaca gggagttggc ccacccactg acaatgaagc ccgtgagctg 2500

 gctgcccagc tagccctgtc tcaggcgcag ctggaagtcc atcaggggga 2550

 ggtccaacgg ctgcaggctc aggtggtgga cctccaggcc aagatgcggg 2600

 cagccctgga tgaccaggac aaggtgcaga gccagctaag catggctgag 2650

 gccgtcctga gggagcacaa aacccttgtg cagcagctga aggagcagaa 2700

 tgaagccctt aacagagccc atgtccagga gctgctgcaa tgctcggagc 2750

 gtgaaggggc actgcaggag gagagggccg atgaggccca gcagagggag 2800

 gaggagctgc gggccctgca ggaggagctg tcccaggcca aatgcagctc 2850

 cgaggaagca cagctggagc acgctgagct gcaagagcag ctgcaccggg 2900

 ccaacacaga cacagctgag ctgggcatcc aggtttgcgc actgaccgtg 2950

 gaaaaggagc gagtggagga ggcactggcc tgtgctgtcc aggagctcca 3000

 ggacgccaaa gaggcagcct caagggagcg agagggcctg gagcgccaag 3050

 tagctgggct gcagcaagag aaggagagct tgcaggagaa gctgaaggcg 3100

 gccaaggcag cagccggctc actgcctggc ctgcaggccc agctcgccca 3150

 ggcagagcag cgggcccaga gcctccaaga ggctgcacac caggagctca 3200

 acaccctcaa gttccagctg agtgctgaaa tcatggacta ccagagcaga 3250

 cttaagaatg ctggtgaaga gtgcaagagc ctcaggggcc agcttgagga 3300

 gcaaggccgg cagctgcagg ctgctgagga agctgtggag aagctgaagg 3350

 ccacccaagc agacatggga gagaagctga gctgcactag caaccatctt 3400

 gcagagtgcc aggcggccat gctgaggaag gacaaggagg gggctgccct 3450

 gcgtgaagac ctagaaagga cccagaagga actcgaaaaa gccacaacaa 3500

 aaatccaaga gtattacaac aaactctgcc aggaggtgac aaatcgtgag 3550

 aggaatgacc agaagatgct tgctgacctg gatgacctca acagaaccaa 3600

 gaagtatctc gaggagcggc tgatagagct gctcagggac aaggatgctc 3650

 tctggcagaa gtcagatgcc ctggaattcc agcagaagct cagtgctgag 3700

 gagagatggc tcggagacac agaggcaaac cactgcctcg actgtaagcg 3750

 ggagttcagc tggatggtgc ggcggcacca ctgcaggata tgtggccgca 3800

 tcttctgtta ctactgctgc aacaactacg tcctgagcaa gcacggtggc 3850

 aaaaaggagc gctgctgccg agcctgtttc cagaagctca gtgaaggccc 3900

 tggctcccct gatagcagtg gctcaggcac tagccaggga gagcccagcc 3950

 ctgcactgtc accagcctca cctgggcccc aggccacagg aggccaagga 4000

 gcaaatacag actacaggcc accggacgac gctgtgtttg atatcatcac 4050

 agatgaggaa ttgtgccaga tacaggagtc cggctcctct ttgcctgaaa 4100

 cacccactga aactgattct cttgacccaa atgcggctga acaggatact 4150

 acatcaacct cgctaacgcc tgaggacact gaagacatgc ccgtggggca 4200

 ggattcggaa atctgcctgc tgaagtctgg agaactgatg atcaaagtac 4250

 ccctcacagt ggatgagatc gccagcttcg gggagggtag cagggagctg 4300

 tttgtgaggt ccagcaccta cagcctgatc cccatcactg tgcccgaggc 4350

 agccctcacc atcagctggg tcttctcctc tgaccccaag agcatctcct 4400

 tcagtgtggt cttccaggag gccgaggaca caccgctgga tcagtgtaag 4450

 gtcctcattc ccacgacccg atgcaactcc cacaaggaga acatccaggg 4500

 ccagctcaag gttcgcacac ccggcatcta catgctcatc ttcgacaata 4550

 ccttctcaag gtttgtctct aaaaaggtat tttatcactt gacggttgat 4600

 cggcctgtga tctacgatgg aagtgatttc ctgtagcttc agcacctcag 4650

 taacttcact tcatccacag gaaacactgc tcttcctcac ctgtcacata 4700

 aagcattttt ttaaaaagtc agctgctcca aaatcatcaa ctcagcccct 4750

 gggctgcccc tcagaggcgg tgtctgggga ggactttgtg ctcagcactc 4800

 tgcaccggcc actcttagcc cccgaggcgt tgaagggctc aggcaatgtt 4850

 tccattaagt agagactcag ctgttgtcac acccaaaggg atgctctgcc 4900

 aaaggtttaa acacccagga gaccatcagc ctctcctggg agcacagttg 4950

 actacaggcc tcttgtggag agtttcacgg gcaggggtga ttccaacttc 5000

 tgcctgtgga gagattttct gccctgcccc accagggccc tgcatgttgg 5050

 agactgagct gggtgcactg gccataccct gtgaatcctc gggctgtgac 5100

 gccctcaggt actcctggga aaaggaggta cacagccatc atgcgagtcg 5150

 gtgccagggg accccccgga gatcctgacc agctcctcca gtcatgctct 5200

 tgtccctcac tgccccagta agctggaggc tgctccagaa ctcagcagtg 5250

 ttggaggggc ctctaagctg cactctcttt ctggcccttt tgtctggctg 5300

 attctgtcct caaataaagc ccttcactca gccagacctc tccacagctc 5350

 aaagcattgc cctaagaatc agaagtaaag ataatccaag agcaaaaccc 5400

 actgtacttg gggcctgcaa tggctgtgtg tacactacat ctaatgccca 5450

 aatgccagcc agtgtggatg ttgtgaccac agagcaggat tgtgcattgg 5500

 ctttagagct actcctcagc tgatggccca cttttgttta tataaataag 5550

 agcttctgcc ccacctgcag acatgtttac taatgatcat agccaggatt 5600

 agaaccactt tcaaacattg gggccttctt aacaaaagtc tttgataact 5650

 taagaaccaa agtaacagag taaacagagg catgatggat ccctgggccc 5700

 cactcccctc ctgacaggtt ccccaacagc ccatttgccc acttcccact 5750

 gctcagccca caccagacct ccaggagaca tccccccttg aggcagagag 5800

 atcctgttcc ctattcccag acaagaatta tttaatcttc cctgttctct 5850

 gtggtccttt tcttccccaa caacagatag ctcaccttgg acagctcttc 5900

 gtcccttgtt catggaacca gctgcctgca gtcaggcccc aggttcttcc 5950

 atgggtgaac agagcatctg acaaaaggtc ccagtttggc caggggtgag 6000

 ggagagagca ccagacaggc tatccgagaa tctgagagct gggcccggca 6050

 attcctccag ctacccttgt gacctaagtc cagtcacaca tttcccaaag 6100

 tttctctttg tcataaccct ggtctggctg gttttgaggg cttgagaatg 6150

 ggtcagggac tccaggccaa gtccaacaga gaccccaaac ccaccacaca 6200

 ccagcagcca caacctcacc accaacaaag aggacttttg tggggccaca 6250

 agtaagaggt catttctgga atggactcag acctttaaac aggagagttg 6300

 agcacttcca gtcagttttt aagcaaggca tggggaacag ggaatagaac 6350

 ctttcaaaga ggttgcccag agaaaagctg ggcctcttgc attcggcttc 6400

 cttggagcag cctcttctgg cagaaagcca tcaggtgctc aatcatcttc 6450

 tcctggccaa ggctctgacc atgcttagta ctggaataga ggtggccagg 6500

 cccccagcga ctcttcttgg cctgatgttt gtcctcacag gcatgccacg 6550

 tggcctgaga tgattcagaa caaatcatgc taactttgaa tccatccagc 6600

 cacttgcaaa tgataatcag aagtcagctt gttcactgtt agaaagaaac 6650

 taacaaaaga gaacccagag caatctagaa tctttgagtg cttggctttc 6700

 caaggatact gcggagactc tggccaagct gatgaccttc tgaagtgtca 6750

 ctggcaccat atgcaacaag aaccaccatt cactgagtag ctaatgggtt 6800

 tggggcctgg gacattccat ctgaggtcct tcctgaacat gtcactccac 6850

 agcagaggac cggttgcagc ttacccagaa ccactcctcc aggagagctg 6900

 gatgttttgc gtgcaacacc ttgagcactg actgctattg ttcaaaaaaa 6950

 gcctttgctg cattcggagg actgccccgt gccctgaggt gacttcctaa 7000

 ctatgtggtt tcattagcga atttattttt tgggctgggt ggacatttgt 7050

 attttgttag gttgctgttt aagctcaagt ttgctgtgct ctctgcagct 7100

 acaaaacatc ttggcatatt taagagtggc ttttataaat agctttattc 7150

 tgatattaat cagattccca actttactga gaattaagga ctggggtact 7200

 ttaaagaaat gcaaatagca attgaagaac cactgctgca ggtggtagcc 7250

 ctggctagac tgaattacac tagaaatcag ccagaaggaa gcgtccttgg 7300

 gatcccagat cactcttttt tttttttttt tttaaaaggg gcagcccctt 7350

 gatggctcat ctctctgaat aacagttacg tcttcatatc gataccagat 7400

 gccttcttca tcatgccact gaagccactc accaccttca agaacatgcc 7450

 aacctctgtc agattcactt acccacaaac aaggaggcac gtttggcaca 7500

 aagtgttgtc ctccaggtcc aagtggactc tacagagtgc ttgacctcaa 7550

 cacactggat tccaggtgga ctggaccaag agcaggcaaa gacacgggaa 7600

 ctgaaaaact ccacagggtt tggagaatag aaatgaaaag ccacgtcata 7650

 taactcaaga ataaatggtg ttttggaaat tttaaaatta tcatcgaagg 7700

 tggtgaaact atttcaggcc caaatgaaag gaaatcgcca gttggggatg 7750

 aaatcacaga gcctgtgttt tatgatatgg ttggatgtcc actgatgaaa 7800

 ttttaaagga gtttcatttt taaaagtgcg catgattcta catatgagaa 7850

 ttctttaggc caagaaactg tccttggctc agaggtgttg ggaattaaag 7900

 cagagagaag ccattcgtga tgcttagaac caaggatggt catgtacaca 7950

 aagaccatcg agacggccat tcttgtttac aaaacactta ccaagaaagc 8000

 actttgtagg ggaactttag taagttcttc tcatttcatt atgtttcttc 8050

 caaggaaaca ggagagactg aattaataat tctctctttc ctcttaagca 8100

 cttttaaaat aataaagtac atcttgaaat ttggggaggc atctctgatt 8150

 taaaaaaaga aaaaggctgc ttgatgtatg ttatgcagag acactctgcc 8200

 tctggtggct gcagagcaat acccaagcct catttggaag gctcaacatt 8250

 tggaattgca ctttaattga ttaatcctca attcatgtgg ccttacggga 8300

 tggtgggtct gggaccccaa ttcattctta tctgccaaag aattatctag 8350

 aagcacatca aataccagca ccccacctgc acaatggggg tggaaaactt 8400

 ttgtatccct aagcatatta ttttatagtg tctgccatgc catgtggaaa 8450

 tactttattt ttaacctcag gatttaaata aagtaaacac tatgacattt 8500

<210> 3182
<211> 1478
<212> PRT
<213> Homo sapien

<400> 3182
 Met Ala Ser Thr Asn Ala Glu Ser Gln Leu Gln Arg Ile Ile Arg
   1               5                  10                  15

 Asp Leu Gln Asp Ala Val Thr Glu Leu Ser Lys Glu Phe Gln Glu
                  20                  25                  30

 Ala Gly Glu Pro Ile Thr Asp Asp Ser Thr Ser Leu His Lys Phe
                  35                  40                  45

 Ser Tyr Lys Leu Glu Tyr Leu Leu Gln Phe Asp Gln Lys Glu Lys
                  50                  55                  60

 Ala Thr Leu Leu Gly Asn Lys Lys Asp Tyr Trp Asp Tyr Phe Cys
                  65                  70                  75

 Ala Cys Leu Ala Lys Val Lys Gly Ala Asn Asp Gly Ile Arg Phe
                  80                  85                  90

 Val Lys Ser Ile Ser Glu Leu Arg Thr Ser Leu Gly Lys Gly Arg
                  95                 100                 105

 Ala Phe Ile Arg Tyr Ser Leu Val His Gln Arg Leu Ala Asp Thr
                 110                 115                 120

 Leu Gln Gln Cys Phe Met Asn Thr Lys Val Thr Ser Asp Trp Tyr
                 125                 130                 135

 Tyr Ala Arg Ser Pro Phe Leu Gln Pro Lys Leu Ser Ser Asp Ile
                 140                 145                 150

 Val Gly Gln Leu Tyr Glu Leu Thr Glu Val Gln Phe Asp Leu Ala
                 155                 160                 165

 Ser Arg Gly Phe Asp Leu Asp Ala Ala Trp Pro Thr Phe Ala Arg
                 170                 175                 180

 Arg Thr Leu Thr Thr Gly Ser Ser Ala Tyr Leu Trp Lys Pro Pro
                 185                 190                 195

 Ser Arg Ser Ser Ser Met Ser Ser Leu Val Ser Ser Tyr Leu Gln
                 200                 205                 210

 Thr Gln Glu Met Val Ser Asn Phe Asp Leu Asn Ser Pro Leu Asn
                 215                 220                 225

 Asn Glu Ala Leu Glu Gly Phe Asp Glu Met Arg Leu Glu Leu Asp
                 230                 235                 240

 Gln Leu Glu Val Arg Glu Lys Gln Leu Gln Glu Arg Met Gln Gln
                 245                 250                 255

 Leu Asp Arg Glu Asn Gln Glu Leu Arg Ala Ala Val Ser Gln Gln
                 260                 265                 270

 Gly Glu Gln Leu Gln Thr Glu Arg Glu Arg Gly Arg Thr Ala Ala
                 275                 280                 285

 Glu Asp Asn Val Arg Leu Thr Cys Leu Val Ala Glu Leu Gln Lys
                 290                 295                 300

 Gln Trp Glu Val Thr Gln Ala Thr Gln Asn Thr Val Lys Glu Leu
                 305                 310                 315

 Gln Thr Cys Leu Gln Ala Leu Glu Leu Gly Ala Ala Glu Lys Glu
                 320                 325                 330

 Glu Asp Tyr His Thr Ala Leu Arg Arg Leu Glu Ser Met Leu Gln
                 335                 340                 345

 Pro Leu Ala Gln Glu Leu Glu Ala Thr Arg Asp Ser Leu Asp Lys
                 350                 355                 360

 Lys Asn Gln His Leu Ala Ser Phe Pro Gly Trp Leu Ala Met Ala
                 365                 370                 375

 Gln Gln Lys Ala Asp Ser Ala Ser Asp Thr Lys Gly Arg Gln Glu
                 380                 385                 390

 Pro Ile Pro Ser Asp Ala Ala Gln Glu Met Gln Glu Leu Gly Glu
                 395                 400                 405

 Lys Leu Gln Ala Leu Glu Arg Glu Arg Thr Lys Val Glu Glu Val
                 410                 415                 420

 Asn Arg Gln Gln Ser Ala Gln Leu Glu Gln Leu Val Lys Glu Leu
                 425                 430                 435

 Gln Leu Lys Glu Asp Ala Arg Ala Ser Leu Glu Arg Leu Val Lys
                 440                 445                 450

 Glu Met Ala Pro Leu Gln Glu Glu Leu Ser Gly Lys Gly Gln Glu
                 455                 460                 465

 Ala Asp Gln Leu Trp Arg Arg Leu Gln Glu Leu Leu Ala His Thr
                 470                 475                 480

 Ser Ser Trp Glu Glu Glu Leu Ala Glu Leu Arg Arg Glu Lys Lys
                 485                 490                 495

 Gln Gln Gln Glu Glu Lys Glu Leu Leu Glu Gln Glu Val Arg Ser
                 500                 505                 510

 Leu Thr Arg Gln Leu Gln Phe Leu Glu Thr Gln Leu Ala Gln Val
                 515                 520                 525

 Ser Gln His Val Ser Asp Leu Glu Glu Gln Lys Lys Gln Leu Ile
                 530                 535                 540

 Gln Asp Lys Asp His Leu Ser Gln Gln Val Gly Met Leu Glu Arg
                 545                 550                 555

 Leu Ala Gly Pro Pro Gly Pro Glu Leu Pro Val Ala Gly Glu Lys
                 560                 565                 570

 Asn Glu Ala Leu Val Pro Val Asn Ser Ser Leu Gln Glu Ala Trp
                 575                 580                 585

 Gly Lys Pro Glu Glu Glu Gln Arg Gly Leu Gln Glu Ala Gln Leu
                 590                 595                 600

 Asp Asp Thr Lys Val Gln Glu Gly Ser Gln Glu Glu Glu Leu Arg
                 605                 610                 615

 Gln Ala Asn Arg Glu Leu Glu Lys Glu Leu Gln Asn Val Val Gly
                 620                 625                 630

 Arg Asn Gln Leu Leu Glu Gly Lys Leu Gln Ala Leu Gln Ala Asp
                 635                 640                 645

 Tyr Gln Ala Leu Gln Gln Arg Glu Ser Ala Ile Gln Gly Ser Leu
                 650                 655                 660

 Ala Ser Leu Glu Ala Glu Gln Ala Ser Ile Arg His Leu Gly Asp
                 665                 670                 675

 Gln Met Glu Ala Ser Leu Leu Ala Val Arg Lys Ala Lys Glu Ala
                 680                 685                 690

 Met Lys Ala Gln Met Ala Glu Lys Glu Ala Ile Leu Gln Ser Lys
                 695                 700                 705

 Glu Gly Glu Cys Gln Gln Leu Arg Glu Glu Val Glu Gln Cys Gln
                 710                 715                 720

 Gln Leu Ala Glu Ala Arg His Arg Glu Leu Arg Ala Leu Glu Ser
                 725                 730                 735

 Gln Cys Gln Gln Gln Thr Gln Leu Ile Glu Val Leu Thr Ala Glu
                 740                 745                 750

 Lys Gly Gln Gln Gly Val Gly Pro Pro Thr Asp Asn Glu Ala Arg
                 755                 760                 765

 Glu Leu Ala Ala Gln Leu Ala Leu Ser Gln Ala Gln Leu Glu Val
                 770                 775                 780

 His Gln Gly Glu Val Gln Arg Leu Gln Ala Gln Val Val Asp Leu
                 785                 790                 795

 Gln Ala Lys Met Arg Ala Ala Leu Asp Asp Gln Asp Lys Val Gln
                 800                 805                 810

 Ser Gln Leu Ser Met Ala Glu Ala Val Leu Arg Glu His Lys Thr
                 815                 820                 825

 Leu Val Gln Gln Leu Lys Glu Gln Asn Glu Ala Leu Asn Arg Ala
                 830                 835                 840

 His Val Gln Glu Leu Leu Gln Cys Ser Glu Arg Glu Gly Ala Leu
                 845                 850                 855

 Gln Glu Glu Arg Ala Asp Glu Ala Gln Gln Arg Glu Glu Glu Leu
                 860                 865                 870

 Arg Ala Leu Gln Glu Glu Leu Ser Gln Ala Lys Cys Ser Ser Glu
                 875                 880                 885

 Glu Ala Gln Leu Glu His Ala Glu Leu Gln Glu Gln Leu His Arg
                 890                 895                 900

 Ala Asn Thr Asp Thr Ala Glu Leu Gly Ile Gln Val Cys Ala Leu
                 905                 910                 915

 Thr Val Glu Lys Glu Arg Val Glu Glu Ala Leu Ala Cys Ala Val
                 920                 925                 930

 Gln Glu Leu Gln Asp Ala Lys Glu Ala Ala Ser Arg Glu Arg Glu
                 935                 940                 945

 Gly Leu Glu Arg Gln Val Ala Gly Leu Gln Gln Glu Lys Glu Ser
                 950                 955                 960

 Leu Gln Glu Lys Leu Lys Ala Ala Lys Ala Ala Ala Gly Ser Leu
                 965                 970                 975

 Pro Gly Leu Gln Ala Gln Leu Ala Gln Ala Glu Gln Arg Ala Gln
                 980                 985                 990

 Ser Leu Gln Glu Ala Ala His Gln Glu Leu Asn Thr Leu Lys Phe
                 995                1000                1005

 Gln Leu Ser Ala Glu Ile Met Asp Tyr Gln Ser Arg Leu Lys Asn
                1010                1015                1020

 Ala Gly Glu Glu Cys Lys Ser Leu Arg Gly Gln Leu Glu Glu Gln
                1025                1030                1035

 Gly Arg Gln Leu Gln Ala Ala Glu Glu Ala Val Glu Lys Leu Lys
                1040                1045                1050

 Ala Thr Gln Ala Asp Met Gly Glu Lys Leu Ser Cys Thr Ser Asn
                1055                1060                1065

 His Leu Ala Glu Cys Gln Ala Ala Met Leu Arg Lys Asp Lys Glu
                1070                1075                1080

 Gly Ala Ala Leu Arg Glu Asp Leu Glu Arg Thr Gln Lys Glu Leu
                1085                1090                1095

 Glu Lys Ala Thr Thr Lys Ile Gln Glu Tyr Tyr Asn Lys Leu Cys
                1100                1105                1110

 Gln Glu Val Thr Asn Arg Glu Arg Asn Asp Gln Lys Met Leu Ala
                1115                1120                1125

 Asp Leu Asp Asp Leu Asn Arg Thr Lys Lys Tyr Leu Glu Glu Arg
                1130                1135                1140

 Leu Ile Glu Leu Leu Arg Asp Lys Asp Ala Leu Trp Gln Lys Ser
                1145                1150                1155

 Asp Ala Leu Glu Phe Gln Gln Lys Leu Ser Ala Glu Glu Arg Trp
                1160                1165                1170

 Leu Gly Asp Thr Glu Ala Asn His Cys Leu Asp Cys Lys Arg Glu
                1175                1180                1185

 Phe Ser Trp Met Val Arg Arg His His Cys Arg Ile Cys Gly Arg
                1190                1195                1200

 Ile Phe Cys Tyr Tyr Cys Cys Asn Asn Tyr Val Leu Ser Lys His
                1205                1210                1215

 Gly Gly Lys Lys Glu Arg Cys Cys Arg Ala Cys Phe Gln Lys Leu
                1220                1225                1230

 Ser Glu Gly Pro Gly Ser Pro Asp Ser Ser Gly Ser Gly Thr Ser
                1235                1240                1245

 Gln Gly Glu Pro Ser Pro Ala Leu Ser Pro Ala Ser Pro Gly Pro
                1250                1255                1260

 Gln Ala Thr Gly Gly Gln Gly Ala Asn Thr Asp Tyr Arg Pro Pro
                1265                1270                1275

 Asp Asp Ala Val Phe Asp Ile Ile Thr Asp Glu Glu Leu Cys Gln
                1280                1285                1290

 Ile Gln Glu Ser Gly Ser Ser Leu Pro Glu Thr Pro Thr Glu Thr
                1295                1300                1305

 Asp Ser Leu Asp Pro Asn Ala Ala Glu Gln Asp Thr Thr Ser Thr
                1310                1315                1320

 Ser Leu Thr Pro Glu Asp Thr Glu Asp Met Pro Val Gly Gln Asp
                1325                1330                1335

 Ser Glu Ile Cys Leu Leu Lys Ser Gly Glu Leu Met Ile Lys Val
                1340                1345                1350

 Pro Leu Thr Val Asp Glu Ile Ala Ser Phe Gly Glu Gly Ser Arg
                1355                1360                1365

 Glu Leu Phe Val Arg Ser Ser Thr Tyr Ser Leu Ile Pro Ile Thr
                1370                1375                1380

 Val Pro Glu Ala Ala Leu Thr Ile Ser Trp Val Phe Ser Ser Asp
                1385                1390                1395

 Pro Lys Ser Ile Ser Phe Ser Val Val Phe Gln Glu Ala Glu Asp
                1400                1405                1410

 Thr Pro Leu Asp Gln Cys Lys Val Leu Ile Pro Thr Thr Arg Cys
                1415                1420                1425

 Asn Ser His Lys Glu Asn Ile Gln Gly Gln Leu Lys Val Arg Thr
                1430                1435                1440

 Pro Gly Ile Tyr Met Leu Ile Phe Asp Asn Thr Phe Ser Arg Phe
                1445                1450                1455

 Val Ser Lys Lys Val Phe Tyr His Leu Thr Val Asp Arg Pro Val
                1460                1465                1470

 Ile Tyr Asp Gly Ser Asp Phe Leu
                1475

<210> 3183
<211> 3257
<212> DNA
<213> Homo sapien

<400> 3183
 ccgggcgcgc cacacttcct gttgatccgg ctcggccggg ggctgggccg 50

 gcgggcaggc ggcggcggcc actggccagg cgtggacgcg cgcggggccg 100

 ccgcgggcac ggagtggccg ccgcgtcgcc tgagcccaga gccggggagt 150

 gctctcggcc gccgcgtctc ctgccctctg tccttccaac ccagccctcg 200

 gctgagccgc gccgcaccat gcccgccgtg gacaagctcc tgctagagga 250

 ggcgttgcag gacagccccc agactcgctc tttactgagc gtgtttgaag 300

 aagatgctgg caccctcaca gactatacca accagctgct ccaggcaatg 350

 cagcgcgtct atggagccca gaatgagatg tgcctggcca cacaacagct 400

 ttctaagcaa ctgctggcat atgaaaaaca gaactttgct cttggcaaag 450

 gtgatgaaga agtaatttca acactccact atttttccaa agtggtggat 500

 gagcttaatc ttctccatac agagctggct aaacagttgg cagacacaat 550

 ggttctacct atcatacaat tccgagaaaa ggatctcaca gaagtaagca 600

 ctttaaagga tctatttgga ctcgctagca atgagcatga cctctcaatg 650

 gcaaaataca gcaggctgcc taagaaaaag gagaatgaga aggtgaagac 700

 cgaagtcgga aaagaggtgg ccgcggcccg gcggaagcag cacctctcct 750

 cccttcagta ctactgtgcc ctcaacgcgc tgcagtacag aaagcaaatg 800

 gccatgatgg agcccatgat aggctttgcc catggacaga ttaacttttt 850

 taagaaggga gcagagatgt tttccaaacg tatggacagc tttttatcct 900

 ccgttgcaga catggttcaa agcattcagg tagaactgga agccgaggcg 950

 gaaaagatgc gggtgtccca gcaagaatta ctttctgttg atgaatctgt 1000

 ttacactcca gactctgatg tggccgcacc acagatcaac aggaacctca 1050

 tccagaaggc tggttacctt aatcttagaa acaaaacagg gctggtcacc 1100

 accacctggg agaggcttta tttcttcacc caaggcggga atctcatgtg 1150

 tcagcccagg ggagccgtgg ctggaggttt gatccaggac ctggacaact 1200

 gctcagtgat ggccgtggat tgcgaagacc ggcgctactg cttccagatc 1250

 accacgccca atggaaaatc gggaataatc ctccaggctg agagcagaaa 1300

 ggaaaatgaa gagtggatat gtgcaataaa caacatctcc agacagatct 1350

 acctgaccga caaccctgag gcagtcgcga tcaagttgaa tcagaccgct 1400

 ctgcaagcag tgactcccat tacaagtttt ggaaaaaaac aagaaagctc 1450

 atgccccagc cagaacctga aaaattcaga gatggaaaat gaaaatgaca 1500

 agattgttcc caaagcaaca gccagtctac ctgaagcaga ggagctgatc 1550

 gcgcctggaa cgccgattca attcgatatt gtgcttcctg ctacagaatt 1600

 ccttgatcag aacagaggga gcaggcgtac caaccctttt ggtgaaactg 1650

 aggatgaatc atttccagaa gcagaagatt ctcttttgca gcagatgttt 1700

 atagttcggt ttttgggatc aatggcagtt aaaacagaca gcactactga 1750

 agtgatttat gaagcgatga gacaagtatt ggctgctcgg gctattcata 1800

 acatcttccg catgacagaa tcccatctga tggtcaccag tcaatctttg 1850

 aggttgatag atccacagac tcaagtatca agggccaatt ttgaacttac 1900

 cagtgtcaca caatttgctg ctcatcaaga aaacaagaga ctggttggtt 1950

 ttgtcatccg tgttcctgaa tccactggag aagaatctct gagtacatac 2000

 atttttgaaa gcaactcaga aggcgaaaag atatgttatg ctattaattt 2050

 gggaaaagaa attattgagg ttcagaagga tccagaagca ctggctcaat 2100

 taatgctgtc cataccacta accaatgatg gaaaatatgt actgttaaac 2150

 gatcaaccag atgacgatga tggaaatcca aatgaacata gaggcgcaga 2200

 atccgaagca taactcactt gcgcctgtgg gggaagagca aacaggaagg 2250

 agagctacct cctaagggtt ttaacgtctc tgacatacag gcacactgac 2300

 ctgatttccg aaggctgaca atcgtttgtg gaatgtaatc ttgatgcctt 2350

 gatactgaga cttgggaggg aaactaagaa atggttgaca gcgttcccac 2400

 ccatctacaa tgttatttta ggtgctttgt ggtaagtctt ttttcttaga 2450

 ttgcgctaaa atttcttaga ttgttcagcg ctcagaacaa aagtttgaaa 2500

 aatgcattgt tcatatgaat gtcatctctt ttcagtttcc agtatccttt 2550

 ttaaaaaatg gcaaaagcct agatttacaa tttgatgaac actaaatatt 2600

 tcttattaat ataatctatt tttgtatttt acttaatgag ctttaagtgc 2650

 ctgtcgttct gaaaattgtg tatttataat tcagcttatc tcacaattgg 2700

 acctaatagc atttctttgt gcagttaggt gacgagcact gctttgaggc 2750

 ccaagcacta gtagagatgc gcgatacagg tctagtttcg gtaactgttc 2800

 cagacatcaa gcaataaaaa aatgaatacc acaaaagatg tttgatttta 2850

 cagtggagcc ttactgaacc agcattcaga agtttaaggt cctcctaggt 2900

 atgagtattt ttagtagtgg atcactgtgg acagggtgca gctctaccag 2950

 ttcctgtttc ttctgagcca gaccctcttc agggaaggga ccaattaatt 3000

 ttaaaactca cttgaagcac agctggtcat ggggcttggt ataaagttcc 3050

 tatttccacc ctgatacttc caattcctgg aaccccagcc cactccccca 3100

 tccctcctcc ctatcaaact agtataatga ttttgaatcg gtacagtgtg 3150

 tttaactgta actaagttca acagactatt attatctttg taataaatta 3200

 acctagcaat aaaaattatt ctgtttcttt aaaaaaaaaa aaaaaaaaaa 3250

 aaaaaaa 3257

<210> 3184
<211> 664
<212> PRT
<213> Homo sapien

<400> 3184
 Met Pro Ala Val Asp Lys Leu Leu Leu Glu Glu Ala Leu Gln Asp
   1               5                  10                  15

 Ser Pro Gln Thr Arg Ser Leu Leu Ser Val Phe Glu Glu Asp Ala
                  20                  25                  30

 Gly Thr Leu Thr Asp Tyr Thr Asn Gln Leu Leu Gln Ala Met Gln
                  35                  40                  45

 Arg Val Tyr Gly Ala Gln Asn Glu Met Cys Leu Ala Thr Gln Gln
                  50                  55                  60

 Leu Ser Lys Gln Leu Leu Ala Tyr Glu Lys Gln Asn Phe Ala Leu
                  65                  70                  75

 Gly Lys Gly Asp Glu Glu Val Ile Ser Thr Leu His Tyr Phe Ser
                  80                  85                  90

 Lys Val Val Asp Glu Leu Asn Leu Leu His Thr Glu Leu Ala Lys
                  95                 100                 105

 Gln Leu Ala Asp Thr Met Val Leu Pro Ile Ile Gln Phe Arg Glu
                 110                 115                 120

 Lys Asp Leu Thr Glu Val Ser Thr Leu Lys Asp Leu Phe Gly Leu
                 125                 130                 135

 Ala Ser Asn Glu His Asp Leu Ser Met Ala Lys Tyr Ser Arg Leu
                 140                 145                 150

 Pro Lys Lys Lys Glu Asn Glu Lys Val Lys Thr Glu Val Gly Lys
                 155                 160                 165

 Glu Val Ala Ala Ala Arg Arg Lys Gln His Leu Ser Ser Leu Gln
                 170                 175                 180

 Tyr Tyr Cys Ala Leu Asn Ala Leu Gln Tyr Arg Lys Gln Met Ala
                 185                 190                 195

 Met Met Glu Pro Met Ile Gly Phe Ala His Gly Gln Ile Asn Phe
                 200                 205                 210

 Phe Lys Lys Gly Ala Glu Met Phe Ser Lys Arg Met Asp Ser Phe
                 215                 220                 225

 Leu Ser Ser Val Ala Asp Met Val Gln Ser Ile Gln Val Glu Leu
                 230                 235                 240

 Glu Ala Glu Ala Glu Lys Met Arg Val Ser Gln Gln Glu Leu Leu
                 245                 250                 255

 Ser Val Asp Glu Ser Val Tyr Thr Pro Asp Ser Asp Val Ala Ala
                 260                 265                 270

 Pro Gln Ile Asn Arg Asn Leu Ile Gln Lys Ala Gly Tyr Leu Asn
                 275                 280                 285

 Leu Arg Asn Lys Thr Gly Leu Val Thr Thr Thr Trp Glu Arg Leu
                 290                 295                 300

 Tyr Phe Phe Thr Gln Gly Gly Asn Leu Met Cys Gln Pro Arg Gly
                 305                 310                 315

 Ala Val Ala Gly Gly Leu Ile Gln Asp Leu Asp Asn Cys Ser Val
                 320                 325                 330

 Met Ala Val Asp Cys Glu Asp Arg Arg Tyr Cys Phe Gln Ile Thr
                 335                 340                 345

 Thr Pro Asn Gly Lys Ser Gly Ile Ile Leu Gln Ala Glu Ser Arg
                 350                 355                 360

 Lys Glu Asn Glu Glu Trp Ile Cys Ala Ile Asn Asn Ile Ser Arg
                 365                 370                 375

 Gln Ile Tyr Leu Thr Asp Asn Pro Glu Ala Val Ala Ile Lys Leu
                 380                 385                 390

 Asn Gln Thr Ala Leu Gln Ala Val Thr Pro Ile Thr Ser Phe Gly
                 395                 400                 405

 Lys Lys Gln Glu Ser Ser Cys Pro Ser Gln Asn Leu Lys Asn Ser
                 410                 415                 420

 Glu Met Glu Asn Glu Asn Asp Lys Ile Val Pro Lys Ala Thr Ala
                 425                 430                 435

 Ser Leu Pro Glu Ala Glu Glu Leu Ile Ala Pro Gly Thr Pro Ile
                 440                 445                 450

 Gln Phe Asp Ile Val Leu Pro Ala Thr Glu Phe Leu Asp Gln Asn
                 455                 460                 465

 Arg Gly Ser Arg Arg Thr Asn Pro Phe Gly Glu Thr Glu Asp Glu
                 470                 475                 480

 Ser Phe Pro Glu Ala Glu Asp Ser Leu Leu Gln Gln Met Phe Ile
                 485                 490                 495

 Val Arg Phe Leu Gly Ser Met Ala Val Lys Thr Asp Ser Thr Thr
                 500                 505                 510

 Glu Val Ile Tyr Glu Ala Met Arg Gln Val Leu Ala Ala Arg Ala
                 515                 520                 525

 Ile His Asn Ile Phe Arg Met Thr Glu Ser His Leu Met Val Thr
                 530                 535                 540

 Ser Gln Ser Leu Arg Leu Ile Asp Pro Gln Thr Gln Val Ser Arg
                 545                 550                 555

 Ala Asn Phe Glu Leu Thr Ser Val Thr Gln Phe Ala Ala His Gln
                 560                 565                 570

 Glu Asn Lys Arg Leu Val Gly Phe Val Ile Arg Val Pro Glu Ser
                 575                 580                 585

 Thr Gly Glu Glu Ser Leu Ser Thr Tyr Ile Phe Glu Ser Asn Ser
                 590                 595                 600

 Glu Gly Glu Lys Ile Cys Tyr Ala Ile Asn Leu Gly Lys Glu Ile
                 605                 610                 615

 Ile Glu Val Gln Lys Asp Pro Glu Ala Leu Ala Gln Leu Met Leu
                 620                 625                 630

 Ser Ile Pro Leu Thr Asn Asp Gly Lys Tyr Val Leu Leu Asn Asp
                 635                 640                 645

 Gln Pro Asp Asp Asp Asp Gly Asn Pro Asn Glu His Arg Gly Ala
                 650                 655                 660

 Glu Ser Glu Ala


<210> 3185
<211> 1377
<212> DNA
<213> Homo sapien

<400> 3185
 ctttgttttg cttcgagatg gctgcgggga tgtatttgga acattatctg 50

 gacagtattg aaaaccttcc ctttgaatta cagagaaact ttcagctcat 100

 gagggaccta gaccaaagaa cagaggacct gaaggctgaa attgacaagt 150

 tggccactga gtatatgagt agtgcccgca gcctgagctc cgaggaaaaa 200

 ttggcccttc tcaaacagat ccaggaagcc tatggcaagt gcaaggaatt 250

 tggtgacgac aaggtgcagc ttgccatgca gacctatgag atggtggaca 300

 aacacattcg gcggctggac acagacctgg cccgttttga ggctgatctc 350

 aaggagaaac agattgagtc aagtgactat gacagctctt ccagcaaagg 400

 caaaaagaaa ggccggactc aaaaggagaa gaaagctgct cgtgctcgtt 450

 ccaaagggaa aaactcggat gaagaagccc ccaagactgc ccagaagaag 500

 ttaaagctcg tgcgcacaag tcctgagtat gggatgccct cagtgacctt 550

 tggcagtgtc cacccctctg atgtgttgga tatgcctgtg gatcccaacg 600

 aacccaccta ttgcctttgt caccaggtct cctatggaga gatgattggc 650

 tgtgacaacc ctgattgttc cattgagtgg ttccattttg cctgtgtggg 700

 gctgacaacc aagcctcggg ggaaatggtt ttgcccacgc tgctcccaag 750

 aacggaagaa gaaatagata agggccttgg attccaacac agtttcttcc 800

 acatcccctg acttgggcta gtgggcagag gaatgcctgt gctggggcca 850

 ggggttcagg gaggagtgga tggcacagtg ctgtcatccc ttctcctccc 900

 ctctccccac tcccggtgct gaggctgcat cagaccctgg tagggagggg 950

 tgccgcagcc actaacggta tgtgctctcc ttcagccctc tccttcggag 1000

 ggacgtggtc ttgcccactg tccttttgcc tccatgctga ggtcggtgct 1050

 gtatttcaga gggagggtcc ttttcattct ccttgctttg tatttaagga 1100

 ctggggcata gcatgggggc agtcccccag acctcttcat tccccctcct 1150

 gtggtgaggg ctaggtgtga tcaacacttt tcttctccat tcccttcctg 1200

 cttttttcat ggtggggatc caccaggtca tctagctctg gccctagttg 1250

 aagggcaccc cttcctctgt gccaagagga ttcatcctgg gagagggggc 1300

 aaggtggaat gcagataact cacatgtaaa aggaacttgg gtaggtaaat 1350

 aaaagctata catgttgaaa aaaaaaa 1377

<210> 3186
<211> 249
<212> PRT
<213> Homo sapien

<400> 3186
 Met Ala Ala Gly Met Tyr Leu Glu His Tyr Leu Asp Ser Ile Glu
   1               5                  10                  15

 Asn Leu Pro Phe Glu Leu Gln Arg Asn Phe Gln Leu Met Arg Asp
                  20                  25                  30

 Leu Asp Gln Arg Thr Glu Asp Leu Lys Ala Glu Ile Asp Lys Leu
                  35                  40                  45

 Ala Thr Glu Tyr Met Ser Ser Ala Arg Ser Leu Ser Ser Glu Glu
                  50                  55                  60

 Lys Leu Ala Leu Leu Lys Gln Ile Gln Glu Ala Tyr Gly Lys Cys
                  65                  70                  75

 Lys Glu Phe Gly Asp Asp Lys Val Gln Leu Ala Met Gln Thr Tyr
                  80                  85                  90

 Glu Met Val Asp Lys His Ile Arg Arg Leu Asp Thr Asp Leu Ala
                  95                 100                 105

 Arg Phe Glu Ala Asp Leu Lys Glu Lys Gln Ile Glu Ser Ser Asp
                 110                 115                 120

 Tyr Asp Ser Ser Ser Ser Lys Gly Lys Lys Lys Gly Arg Thr Gln
                 125                 130                 135

 Lys Glu Lys Lys Ala Ala Arg Ala Arg Ser Lys Gly Lys Asn Ser
                 140                 145                 150

 Asp Glu Glu Ala Pro Lys Thr Ala Gln Lys Lys Leu Lys Leu Val
                 155                 160                 165

 Arg Thr Ser Pro Glu Tyr Gly Met Pro Ser Val Thr Phe Gly Ser
                 170                 175                 180

 Val His Pro Ser Asp Val Leu Asp Met Pro Val Asp Pro Asn Glu
                 185                 190                 195

 Pro Thr Tyr Cys Leu Cys His Gln Val Ser Tyr Gly Glu Met Ile
                 200                 205                 210

 Gly Cys Asp Asn Pro Asp Cys Ser Ile Glu Trp Phe His Phe Ala
                 215                 220                 225

 Cys Val Gly Leu Thr Thr Lys Pro Arg Gly Lys Trp Phe Cys Pro
                 230                 235                 240

 Arg Cys Ser Gln Glu Arg Lys Lys Lys
                 245

<210> 3187
<211> 2414
<212> DNA
<213> Homo sapien

<400> 3187
 cccgcgtgca tacggttgcc ggcatggcac attacaactt caagaaaatt 50

 acggtggtgc cgtccgccaa ggacttcata gacctcacgt tgtcgaagac 100

 tcaacgaaag actccaaccg ttattcataa acattaccaa atacatcgca 150

 ttagacattt ttacatgaga aaagtcaaat ttactcaaca gaattaccat 200

 gatagacttt cacaaattct aacagatttc cccaaattgg atgatattca 250

 tccgttctat gctgatttga tgaatattct ctacgacaag gatcattaca 300

 agttggctct ggggcaaata aatattgcca aaaatttagt ggacaatgtt 350

 gctaaagatt atgtgcgact gatgaagtat ggcgactctc tctaccgctg 400

 caaacagctg aagcgtgcgg ccctgggacg gatgtgcaca gtgatcaaga 450

 ggcagaagca gagtttggag tatttggagc aagtgcgtca gcatttatcc 500

 cgtttgccaa ccattgatcc gaataccagg accctgcttt tgtgtgggta 550

 cccaaatgtt gggaagtcca gcttcatcaa caaggtgacg agagcagacg 600

 tggatgtcca gccctatgcg ttcacaacca agtctctgtt tgttgggcac 650

 atggattata agtatctacg ttggcaggtt gtagacactc ctgggatcct 700

 ggaccaccct ctggaggata ggaacaccat cgagatgcag gccatcactg 750

 ccctggccca cctccgtgct gcggtcctgt atgtgatgga tttgtctgag 800

 cagtgtgggc atgggctgag ggagcagcta gaactcttcc agaacatcag 850

 acctctcttc atcaacaagc ctctcatagt tgtagccaac aaatgtgatg 900

 tgaagagaat agctgaactt tctgaagatg atcagaaaat atttacagat 950

 ttgcagtctg aaggattccc tgtaatagag accagcaccc tgactgagga 1000

 aggtgttatt aaagttaaaa cagaggcttg cgataggctt ttggctcatc 1050

 gagtggaaac caaaatgaag ggaaataaag tgaatgaggt gctgaataga 1100

 ctgcacctgg ctatcccaac caggagggac gataaggaga ggcccccttt 1150

 catccctgaa ggagtggtgg ctcgcaggaa gaggatggaa actgaggagt 1200

 ccaggaagaa gagggaacga gatcttgagc tggaaatggg agatgattat 1250

 attttggatc ttcagaagta ctgggattta atgaatttgt ctgaaaaaca 1300

 tgataagata ccagaaatct gggaaggcca taatatagct gattatattg 1350

 atccagccat catgaagaaa ttggaagaat tagaaaaaga agaagagctg 1400

 agaacagctg ctggagagta tgacagtgta tctgagagtg aagacgaaga 1450

 gatgctggaa atccgacagc tggcaaagca aattcgagag aaaaagaagt 1500

 tgaaaattct ggagtccaaa gaaaagaata cacagggacc caggatgccg 1550

 cgaactgcta agaaggttca gaggacagtt ttggagaagg agatgcgtag 1600

 tcttggtgtt gacatggacg ataaagacga tgcccattac gcagtccagg 1650

 caagaagatc ccggagcatc actaggaaaa gaaagcggga agactctgct 1700

 cccccgtcct ctgtggcccg gagtgggagt tgctctcgaa ctccacgtga 1750

 cgtttctggt cttagggatg tcaagatggt gaagaaagcc aagactatga 1800

 agaatgctca gaagaagatg aatcggttgg ggaagaaagg ggaggcggat 1850

 agacacgtgt ttgatatgaa gcccaagcac ttgctgtctg ggaagaggaa 1900

 agctggtaaa aaggacagga gatagtatcc gtttggttgg cgtggcttcg 1950

 ctagagtgtt gctgtttatt tcctggtttg gtacagtatg gtttcatgaa 2000

 attggagctc tgtacaaact gaaaaagaca aaataagtaa agcacttgtt 2050

 gctttgctga aaactatggt taaccctata taggtgtggg aaatttttgt 2100

 cactgcataa tattacaaat attttgagta gacagtgttt ccacatttaa 2150

 tggagtatca gttgcttcag attttcagaa ctgggaagat ttactggtgt 2200

 aactgggttg tttttgatgg agaaaaacct tattttcttt tgtaagagct 2250

 gggagcaaac acgtttatga gtgtgtcgga atcccgtgct taaaatacgc 2300

 tcttaaatta ttttctagtc ttattttaca atgtctcatt gtagtctgtc 2350

 ttcaactatt ttatccaaaa taaacctcca gaagaaacta aaaaaaaaaa 2400

 aaaaaaaaaa aaaa 2414

<210> 3188
<211> 633
<212> PRT
<213> Homo sapien

<400> 3188
 Met Ala His Tyr Asn Phe Lys Lys Ile Thr Val Val Pro Ser Ala
   1               5                  10                  15

 Lys Asp Phe Ile Asp Leu Thr Leu Ser Lys Thr Gln Arg Lys Thr
                  20                  25                  30

 Pro Thr Val Ile His Lys His Tyr Gln Ile His Arg Ile Arg His
                  35                  40                  45

 Phe Tyr Met Arg Lys Val Lys Phe Thr Gln Gln Asn Tyr His Asp
                  50                  55                  60

 Arg Leu Ser Gln Ile Leu Thr Asp Phe Pro Lys Leu Asp Asp Ile
                  65                  70                  75

 His Pro Phe Tyr Ala Asp Leu Met Asn Ile Leu Tyr Asp Lys Asp
                  80                  85                  90

 His Tyr Lys Leu Ala Leu Gly Gln Ile Asn Ile Ala Lys Asn Leu
                  95                 100                 105

 Val Asp Asn Val Ala Lys Asp Tyr Val Arg Leu Met Lys Tyr Gly
                 110                 115                 120

 Asp Ser Leu Tyr Arg Cys Lys Gln Leu Lys Arg Ala Ala Leu Gly
                 125                 130                 135

 Arg Met Cys Thr Val Ile Lys Arg Gln Lys Gln Ser Leu Glu Tyr
                 140                 145                 150

 Leu Glu Gln Val Arg Gln His Leu Ser Arg Leu Pro Thr Ile Asp
                 155                 160                 165

 Pro Asn Thr Arg Thr Leu Leu Leu Cys Gly Tyr Pro Asn Val Gly
                 170                 175                 180

 Lys Ser Ser Phe Ile Asn Lys Val Thr Arg Ala Asp Val Asp Val
                 185                 190                 195

 Gln Pro Tyr Ala Phe Thr Thr Lys Ser Leu Phe Val Gly His Met
                 200                 205                 210

 Asp Tyr Lys Tyr Leu Arg Trp Gln Val Val Asp Thr Pro Gly Ile
                 215                 220                 225

 Leu Asp His Pro Leu Glu Asp Arg Asn Thr Ile Glu Met Gln Ala
                 230                 235                 240

 Ile Thr Ala Leu Ala His Leu Arg Ala Ala Val Leu Tyr Val Met
                 245                 250                 255

 Asp Leu Ser Glu Gln Cys Gly His Gly Leu Arg Glu Gln Leu Glu
                 260                 265                 270

 Leu Phe Gln Asn Ile Arg Pro Leu Phe Ile Asn Lys Pro Leu Ile
                 275                 280                 285

 Val Val Ala Asn Lys Cys Asp Val Lys Arg Ile Ala Glu Leu Ser
                 290                 295                 300

 Glu Asp Asp Gln Lys Ile Phe Thr Asp Leu Gln Ser Glu Gly Phe
                 305                 310                 315

 Pro Val Ile Glu Thr Ser Thr Leu Thr Glu Glu Gly Val Ile Lys
                 320                 325                 330

 Val Lys Thr Glu Ala Cys Asp Arg Leu Leu Ala His Arg Val Glu
                 335                 340                 345

 Thr Lys Met Lys Gly Asn Lys Val Asn Glu Val Leu Asn Arg Leu
                 350                 355                 360

 His Leu Ala Ile Pro Thr Arg Arg Asp Asp Lys Glu Arg Pro Pro
                 365                 370                 375

 Phe Ile Pro Glu Gly Val Val Ala Arg Arg Lys Arg Met Glu Thr
                 380                 385                 390

 Glu Glu Ser Arg Lys Lys Arg Glu Arg Asp Leu Glu Leu Glu Met
                 395                 400                 405

 Gly Asp Asp Tyr Ile Leu Asp Leu Gln Lys Tyr Trp Asp Leu Met
                 410                 415                 420

 Asn Leu Ser Glu Lys His Asp Lys Ile Pro Glu Ile Trp Glu Gly
                 425                 430                 435

 His Asn Ile Ala Asp Tyr Ile Asp Pro Ala Ile Met Lys Lys Leu
                 440                 445                 450

 Glu Glu Leu Glu Lys Glu Glu Glu Leu Arg Thr Ala Ala Gly Glu
                 455                 460                 465

 Tyr Asp Ser Val Ser Glu Ser Glu Asp Glu Glu Met Leu Glu Ile
                 470                 475                 480

 Arg Gln Leu Ala Lys Gln Ile Arg Glu Lys Lys Lys Leu Lys Ile
                 485                 490                 495

 Leu Glu Ser Lys Glu Lys Asn Thr Gln Gly Pro Arg Met Pro Arg
                 500                 505                 510

 Thr Ala Lys Lys Val Gln Arg Thr Val Leu Glu Lys Glu Met Arg
                 515                 520                 525

 Ser Leu Gly Val Asp Met Asp Asp Lys Asp Asp Ala His Tyr Ala
                 530                 535                 540

 Val Gln Ala Arg Arg Ser Arg Ser Ile Thr Arg Lys Arg Lys Arg
                 545                 550                 555

 Glu Asp Ser Ala Pro Pro Ser Ser Val Ala Arg Ser Gly Ser Cys
                 560                 565                 570

 Ser Arg Thr Pro Arg Asp Val Ser Gly Leu Arg Asp Val Lys Met
                 575                 580                 585

 Val Lys Lys Ala Lys Thr Met Lys Asn Ala Gln Lys Lys Met Asn
                 590                 595                 600

 Arg Leu Gly Lys Lys Gly Glu Ala Asp Arg His Val Phe Asp Met
                 605                 610                 615

 Lys Pro Lys His Leu Leu Ser Gly Lys Arg Lys Ala Gly Lys Lys
                 620                 625                 630

 Asp Arg Arg


<210> 3189
<211> 2414
<212> DNA
<213> Homo sapien

<400> 3189
 cccgcgtgca tacggttgcc ggcatggcac attacaactt caagaaaatt 50

 acggtggtgc cgtccgccaa ggacttcata gacctcacgt tgtcgaagac 100

 tcaacgaaag actccaaccg ttattcataa acattaccaa atacatcgca 150

 ttagacattt ttacatgaga aaagtcaaat ttactcaaca gaattaccat 200

 gatagacttt cacaaattct aacagatttc cccaaattgg atgatattca 250

 tccgttctat gctgatttga tgaatattct ctacgacaag gatcattaca 300

 agttggctct ggggcaaata aatattgcca aaaatttagt ggacaatgtt 350

 gctaaagatt atgtgcgact gatgaagtat ggcgactctc tctaccgctg 400

 caaacagctg aagcgtgcgg ccctgggacg gatgtgcaca gtgatcaaga 450

 ggcagaagca gagtttggag tatttggagc aagtgcgtca gcatttatcc 500

 cgtttgccaa ccattgatcc gaataccagg accctgcttt tgtgtgggta 550

 cccaaatgtt gggaagtcca gcttcatcaa caaggtgacg agagcagacg 600

 tggatgtcca gccctatgcg ttcacaacca agtctctgtt tgttgggcac 650

 atggattata agtatctacg ttggcaggtt gtagacactc ctgggatcct 700

 ggaccaccct ctggaggata ggaacaccat cgagatgcag gccatcactg 750

 ccctggccca cctccgtgct gcggtcctgt atgtgatgga tttgtctgag 800

 cagtgtgggc atgggctgag ggagcagcta gaactcttcc agaacatcag 850

 acctctcttc atcaacaagc ctctcatagt tgtagccaac aaatgtgatg 900

 tgaagagaat agctgaactt tctgaagatg atcagaaaat atttacagat 950

 ttgcagtctg aaggattccc tgtaatagag accagcaccc tgactgagga 1000

 aggtgttatt aaagttaaaa cagaggcttg cgataggctt ttggctcatc 1050

 gagtggaaac caaaatgaag ggaaataaag tgaatgaggt gctgaataga 1100

 ctgcacctgg ctatcccaac caggagggac gataaggaga ggcccccttt 1150

 catccctgaa ggagtggtgg ctcgcaggaa gaggatggaa actgaggagt 1200

 ccaggaagaa gagggaacga gatcttgagc tggaaatggg agatgattat 1250

 attttggatc ttcagaagta ctgggattta atgaatttgt ctgaaaaaca 1300

 tgataagata ccagaaatct gggaaggcca taatatagct gattatattg 1350

 atccagccat catgaagaaa ttggaagaat tagaaaaaga agaagagctg 1400

 agaacagctg ctggagagta tgacagtgta tctgagagtg aagacgaaga 1450

 gatgctggaa atccgacagc tggcaaagca aattcgagag aaaaagaagt 1500

 tgaaaattct ggagtccaaa gaaaagaata cacagggacc caggatgccg 1550

 cgaactgcta agaaggttca gaggacagtt ttggagaagg agatgcgtag 1600

 tcttggtgtt gacatggacg ataaagacga tgcccattac gcagtccagg 1650

 caagaagatc ccggagcatc actaggaaaa gaaagcggga agactctgct 1700

 cccccgtcct ctgtggcccg gagtgggagt tgctctcgaa ctccacgtga 1750

 cgtttctggt cttagggatg tcaagatggt gaagaaagcc aagactatga 1800

 agaatgctca gaagaagatg aatcggttgg ggaagaaagg ggaggcggat 1850

 agacacgtgt ttgatatgaa gcccaagcac ttgctgtctg ggaagaggaa 1900

 agctggtaaa aaggacagga gatagtatcc gtttggttgg cgtggcttcg 1950

 ctagagtgtt gctgtttatt tcctggtttg gtacagtatg gtttcatgaa 2000

 attggagctc tgtacaaact gaaaaagaca aaataagtaa agcacttgtt 2050

 gctttgctga aaactatggt taaccctata taggtgtggg aaatttttgt 2100

 cactgcataa tattacaaat attttgagta gacagtgttt ccacatttaa 2150

 tggagtatca gttgcttcag attttcagaa ctgggaagat ttactggtgt 2200

 aactgggttg tttttgatgg agaaaaacct tattttcttt tgtaagagct 2250

 gggagcaaac acgtttatga gtgtgtcgga atcccgtgct taaaatacgc 2300

 tcttaaatta ttttctagtc ttattttaca atgtctcatt gtagtctgtc 2350

 ttcaactatt ttatccaaaa taaacctcca gaagaaacta aaaaaaaaaa 2400

 aaaaaaaaaa aaaa 2414

<210> 3190
<211> 633
<212> PRT
<213> Homo sapien

<400> 3190
 Met Ala His Tyr Asn Phe Lys Lys Ile Thr Val Val Pro Ser Ala
   1               5                  10                  15

 Lys Asp Phe Ile Asp Leu Thr Leu Ser Lys Thr Gln Arg Lys Thr
                  20                  25                  30

 Pro Thr Val Ile His Lys His Tyr Gln Ile His Arg Ile Arg His
                  35                  40                  45

 Phe Tyr Met Arg Lys Val Lys Phe Thr Gln Gln Asn Tyr His Asp
                  50                  55                  60

 Arg Leu Ser Gln Ile Leu Thr Asp Phe Pro Lys Leu Asp Asp Ile
                  65                  70                  75

 His Pro Phe Tyr Ala Asp Leu Met Asn Ile Leu Tyr Asp Lys Asp
                  80                  85                  90

 His Tyr Lys Leu Ala Leu Gly Gln Ile Asn Ile Ala Lys Asn Leu
                  95                 100                 105

 Val Asp Asn Val Ala Lys Asp Tyr Val Arg Leu Met Lys Tyr Gly
                 110                 115                 120

 Asp Ser Leu Tyr Arg Cys Lys Gln Leu Lys Arg Ala Ala Leu Gly
                 125                 130                 135

 Arg Met Cys Thr Val Ile Lys Arg Gln Lys Gln Ser Leu Glu Tyr
                 140                 145                 150

 Leu Glu Gln Val Arg Gln His Leu Ser Arg Leu Pro Thr Ile Asp
                 155                 160                 165

 Pro Asn Thr Arg Thr Leu Leu Leu Cys Gly Tyr Pro Asn Val Gly
                 170                 175                 180

 Lys Ser Ser Phe Ile Asn Lys Val Thr Arg Ala Asp Val Asp Val
                 185                 190                 195

 Gln Pro Tyr Ala Phe Thr Thr Lys Ser Leu Phe Val Gly His Met
                 200                 205                 210

 Asp Tyr Lys Tyr Leu Arg Trp Gln Val Val Asp Thr Pro Gly Ile
                 215                 220                 225

 Leu Asp His Pro Leu Glu Asp Arg Asn Thr Ile Glu Met Gln Ala
                 230                 235                 240

 Ile Thr Ala Leu Ala His Leu Arg Ala Ala Val Leu Tyr Val Met
                 245                 250                 255

 Asp Leu Ser Glu Gln Cys Gly His Gly Leu Arg Glu Gln Leu Glu
                 260                 265                 270

 Leu Phe Gln Asn Ile Arg Pro Leu Phe Ile Asn Lys Pro Leu Ile
                 275                 280                 285

 Val Val Ala Asn Lys Cys Asp Val Lys Arg Ile Ala Glu Leu Ser
                 290                 295                 300

 Glu Asp Asp Gln Lys Ile Phe Thr Asp Leu Gln Ser Glu Gly Phe
                 305                 310                 315

 Pro Val Ile Glu Thr Ser Thr Leu Thr Glu Glu Gly Val Ile Lys
                 320                 325                 330

 Val Lys Thr Glu Ala Cys Asp Arg Leu Leu Ala His Arg Val Glu
                 335                 340                 345

 Thr Lys Met Lys Gly Asn Lys Val Asn Glu Val Leu Asn Arg Leu
                 350                 355                 360

 His Leu Ala Ile Pro Thr Arg Arg Asp Asp Lys Glu Arg Pro Pro
                 365                 370                 375

 Phe Ile Pro Glu Gly Val Val Ala Arg Arg Lys Arg Met Glu Thr
                 380                 385                 390

 Glu Glu Ser Arg Lys Lys Arg Glu Arg Asp Leu Glu Leu Glu Met
                 395                 400                 405

 Gly Asp Asp Tyr Ile Leu Asp Leu Gln Lys Tyr Trp Asp Leu Met
                 410                 415                 420

 Asn Leu Ser Glu Lys His Asp Lys Ile Pro Glu Ile Trp Glu Gly
                 425                 430                 435

 His Asn Ile Ala Asp Tyr Ile Asp Pro Ala Ile Met Lys Lys Leu
                 440                 445                 450

 Glu Glu Leu Glu Lys Glu Glu Glu Leu Arg Thr Ala Ala Gly Glu
                 455                 460                 465

 Tyr Asp Ser Val Ser Glu Ser Glu Asp Glu Glu Met Leu Glu Ile
                 470                 475                 480

 Arg Gln Leu Ala Lys Gln Ile Arg Glu Lys Lys Lys Leu Lys Ile
                 485                 490                 495

 Leu Glu Ser Lys Glu Lys Asn Thr Gln Gly Pro Arg Met Pro Arg
                 500                 505                 510

 Thr Ala Lys Lys Val Gln Arg Thr Val Leu Glu Lys Glu Met Arg
                 515                 520                 525

 Ser Leu Gly Val Asp Met Asp Asp Lys Asp Asp Ala His Tyr Ala
                 530                 535                 540

 Val Gln Ala Arg Arg Ser Arg Ser Ile Thr Arg Lys Arg Lys Arg
                 545                 550                 555

 Glu Asp Ser Ala Pro Pro Ser Ser Val Ala Arg Ser Gly Ser Cys
                 560                 565                 570

 Ser Arg Thr Pro Arg Asp Val Ser Gly Leu Arg Asp Val Lys Met
                 575                 580                 585

 Val Lys Lys Ala Lys Thr Met Lys Asn Ala Gln Lys Lys Met Asn
                 590                 595                 600

 Arg Leu Gly Lys Lys Gly Glu Ala Asp Arg His Val Phe Asp Met
                 605                 610                 615

 Lys Pro Lys His Leu Leu Ser Gly Lys Arg Lys Ala Gly Lys Lys
                 620                 625                 630

 Asp Arg Arg


<210> 3191
<211> 4764
<212> DNA
<213> Homo sapien

<400> 3191
 ctgtcttggt acctgcggta gtagcctggc tttgctctga cggcgatctc 50

 gcggcccgag agccttttat aggttgcttt tcccggggat gtgaaggata 100

 cagaaatgac tgtgaatcaa cccatatcat caaggagctg ataatctagt 150

 ggaagagtta gacgtgtgca tacttcacta tgatatgagg cagtctctga 200

 gcttatattc tctgtggaag atgtgacata tccaggcgga acatcatgat 250

 gcagggaaac acatgtcaca gaatgtcgtt ccacccggga cgagggtgtc 300

 cccgaggacg aggaggacat ggagccagac cctcagcacc atcctttagg 350

 ccccaaaatc tgaggctgct tcaccctcag cagcctcctg tgcaatatca 400

 atatgaacct ccaagtgccc cttccaccac tttctcaaac tctccagccc 450

 ccaattttct ccctccacga ccagactttg tacccttccc cccacccatg 500

 cctccgtcag cgcaaggccc tcttcccccc tgcccaatca ggccgccttt 550

 ccccaaccac cagatgaggc accccttccc agttcctcct tgttttcctc 600

 ccatgccacc accaatgcct tgtcctaata accccccagt ccctggggca 650

 cctcctggac aaggcacttt ccccttcatg atgccccctc cctccatgcc 700

 tcatcccccg ccccctccag tcatgccgca gcaggttaat tatcagtacc 750

 ctccgggcta ttctcaccac aacttcccac ctcccagttt taatagtttc 800

 cagaacaacc ctagttcttt cctgcccagt gctaataaca gcagtagtcc 850

 tcatttcaga catctccctc catacccact cccaaaggct cccagtgaga 900

 gaaggtcccc agaaaggctg aaacactatg atgaccacag gcaccgagat 950

 cacagtcatg ggcgaggtga gaggcatcgg tccctggatc ggcgggagcg 1000

 aggccgcagt cccgacagga gaagacaaga cagccggtac agatctgatt 1050

 atgaccgagg gagaacacca tctcgccacc gcagctacga acggagcaga 1100

 gagcgagaac gggagagaca caggcatcga gacaaccgaa gatcaccatc 1150

 tctggaaagg tcctacaaaa aagagtataa gagatctgga aggagttacg 1200

 gtttatcggt tgttcctgaa cctgctggat gcacaccaga attacctggg 1250

 gagattatta aaaatacaga ttcttgggcc ccacccctgg agattgtgaa 1300

 tcatcgctcc ccaagtaggg agaagaagag agctcgttgg gaggaagaaa 1350

 aagaccgttg gagtgacaac cagagttctg gcaaagacaa gaactatacc 1400

 tcaatcaagg aaaaagagcc cgaggagacc atgcctgaca agaatgagga 1450

 ggaagaagaa gaacttctta agcctgtgtg gattcgatgc actcattcag 1500

 aaaactacta ctccagtgac cccatggatc aggtgggaga ttctacagtg 1550

 gttggaacga gtaggcttcg tgacttatat gacaaatttg aggaggagtt 1600

 ggggagcagg caagaaaagg ccaaagctgc tcggcctccg tgggaacctc 1650

 caaagacgaa gctcgatgaa gatttagaga gttccagtga atccgagtgt 1700

 gagtctgatg aggacagcac ctgttctagc agctcagact ctgaagtttt 1750

 tgacgttatt gcagaaatca aacgcaaaaa ggcccaccct gaccgacttc 1800

 atgatgaact ttggtacaac gatccaggcc agatgaatga tggaccactc 1850

 tgcaaatgca gcgcaaaggc aagacgcaca ggaattaggc acagcattta 1900

 tcctggagaa gaggccatca agccctgtcg tcctatgacc aacaatgctg 1950

 gcagactttt ccactaccgg atcacagtct ccccgcctac gaacttttta 2000

 actgacaggc caactgttat agaatacgat gatcacgagt atatctttga 2050

 aggattttct atgtttgcac atgcccccct gaccaatatt ccactgtgta 2100

 aagtaattag attcaacata gactacacga ttcatttcat tgaagagatg 2150

 atgccggaga atttttgtgt gaaagggctt gaactctttt cactgttcct 2200

 attcagagat attttggaat tatatgactg gaatcttaaa ggtcctttgt 2250

 ttgaagacag ccctccctgc tgcccaagat ttcatttcat gccacgtttt 2300

 gtaagatttc ttccagatgg aggaaaggaa gtgctgtcca tgcaccagat 2350

 tctcctgtac ttgttaaggt gcagcaaagc cctggtgcct gaggaggaga 2400

 ttgccaatat gcttcagtgg gaggagctgg agtggcagaa atatgcagaa 2450

 gaatgcaaag gcatgattgt taccaaccct gggacgaaac caagctctgt 2500

 ccgtatcgat caactggatc gtgaacagtt caaccccgat gtgattactt 2550

 ttccgattat cgtccacttt gggatacgcc ctgcacagtt gagttatgca 2600

 ggagacccac agtaccaaaa actgtggaag agttatgtga aacttcgcca 2650

 cctcctagca aatagtccca aagtcaaaca aactgacaaa cagaagctgg 2700

 cacagaggga ggaagccctc caaaaaatac ggcagaagaa tacaatgaga 2750

 cgagaagtaa cggtggagct aagtagccaa ggattctgga aaactggcat 2800

 ccgttctgat gtctgtcagc atgcaatgat gctacctgtt ctgacccatc 2850

 atatccgcta ccaccaatgc ctaatgcatt tggacaagtt gataggatat 2900

 actttccaag atcgttgtct gttgcagctg gccatgactc atccaagtca 2950

 tcatttaaat tttggaatga atcctgatca tgccaggaat tcattatcta 3000

 actgtggaat tcggcagccc aaatacggag acagaaaagt tcatcacatg 3050

 cacatgcgga agaaagggat taacaccttg ataaatatca tgtcacgcct 3100

 tggccaagat gacccaactc cctcgaggat taaccacaat gaacggttgg 3150

 aattcctggg tgatgctgtt gttgaatttc tgaccagcgt ccatttgtac 3200

 tatttgtttc ctagtctgga agaaggagga ttagcaacct atcggactgc 3250

 cattgttcag aatcagcacc ttgccatgct agcaaagaaa cttgaactgg 3300

 atccatttat gctgtatgct cacgggcctg acctttgtag agaatcggac 3350

 cttcgacatg caatggccaa ttgttttgaa gcgttaatag gagctgttta 3400

 cttggaggga agcctggagg aagccaagca gttatttgga cgcttgctct 3450

 ttaatgatcc ggacctgcgc gaagtctggc tcaattatcc tctccaccca 3500

 ctccaactac aagagccaaa tactgatcga caacttattg aaacttctcc 3550

 agttctacaa aaacttactg agtttgaaga agcaattgga gtaattttta 3600

 ctcatgttcg acttctggca agggcattca cattgagaac tgtgggattt 3650

 aaccatctga ccctaggcca caatcagaga atggaattcc taggtgactc 3700

 cataatgcaa ctggtagcca cagagtactt attcattcat ttcccagatc 3750

 atcatgaagg acacttaact ttgttgcgaa gctctttggt gaataataga 3800

 actcaggcca aggtagcgga ggagctgggc atgcaggagt acgccataac 3850

 caacgacaag accaagaggc ctgtggcgct tcgcaccaag accttggcgg 3900

 accttttgga atcatttatt gcagcgctgt acactgataa ggatttggaa 3950

 tatgttcata ctttcatgaa tgtctgcttc tttccacgat tgaaagaatt 4000

 cattttgaat caggattgga atgaccccaa atcccagctt cagcagtgtt 4050

 gcttgacact taggacagaa ggaaaagagc cagacattcc tctgtacaag 4100

 actctgcaga cagtgggccc atcccatgcc cgaacctaca ctgtggctgt 4150

 ttatttcaag ggagaaagaa taggctgtgg gaaaggacca agtattcagc 4200

 aagcggaaat gggagcagca atggatgcgc ttgaaaaata taattttccc 4250

 cagatggccc atcagaagcg gttcatcgaa cggaagtaca gacaagagtt 4300

 aaaagaaatg aggtgggaaa gagagcatca agagagagag ccagatgaga 4350

 ctgaagacat caagaaataa aggagggcat gcaagtgtgg agtatttact 4400

 tgctcagtaa ctgtgactgt tgtctattga gacctagcct agttttcctg 4450

 cagacaatga acgaagtgtg ctcattgaaa taaaatacag agtcaaatcg 4500

 ctattgttgt tttaatgatc tgtttttagc tggatggtct ttattacaaa 4550

 gtattagatt tttcttctat ttaacggaaa acttgacttt ggtgaatgtg 4600

 cattacttcc ttttattttg ctctttaaat aataaaattc aagaagcata 4650

 ttctatgtgg aatagatcct gtttttccat ctgtgtccca gattgtgacc 4700

 ctagactttc aattgacaag taaaaaattg actttactag taaaaaaaaa 4750

 aaaaaaaaaa aaaa 4764

<210> 3192
<211> 1374
<212> PRT
<213> Homo sapien

<400> 3192
 Met Met Gln Gly Asn Thr Cys His Arg Met Ser Phe His Pro Gly
   1               5                  10                  15

 Arg Gly Cys Pro Arg Gly Arg Gly Gly His Gly Ala Arg Pro Ser
                  20                  25                  30

 Ala Pro Ser Phe Arg Pro Gln Asn Leu Arg Leu Leu His Pro Gln
                  35                  40                  45

 Gln Pro Pro Val Gln Tyr Gln Tyr Glu Pro Pro Ser Ala Pro Ser
                  50                  55                  60

 Thr Thr Phe Ser Asn Ser Pro Ala Pro Asn Phe Leu Pro Pro Arg
                  65                  70                  75

 Pro Asp Phe Val Pro Phe Pro Pro Pro Met Pro Pro Ser Ala Gln
                  80                  85                  90

 Gly Pro Leu Pro Pro Cys Pro Ile Arg Pro Pro Phe Pro Asn His
                  95                 100                 105

 Gln Met Arg His Pro Phe Pro Val Pro Pro Cys Phe Pro Pro Met
                 110                 115                 120

 Pro Pro Pro Met Pro Cys Pro Asn Asn Pro Pro Val Pro Gly Ala
                 125                 130                 135

 Pro Pro Gly Gln Gly Thr Phe Pro Phe Met Met Pro Pro Pro Ser
                 140                 145                 150

 Met Pro His Pro Pro Pro Pro Pro Val Met Pro Gln Gln Val Asn
                 155                 160                 165

 Tyr Gln Tyr Pro Pro Gly Tyr Ser His His Asn Phe Pro Pro Pro
                 170                 175                 180

 Ser Phe Asn Ser Phe Gln Asn Asn Pro Ser Ser Phe Leu Pro Ser
                 185                 190                 195

 Ala Asn Asn Ser Ser Ser Pro His Phe Arg His Leu Pro Pro Tyr
                 200                 205                 210

 Pro Leu Pro Lys Ala Pro Ser Glu Arg Arg Ser Pro Glu Arg Leu
                 215                 220                 225

 Lys His Tyr Asp Asp His Arg His Arg Asp His Ser His Gly Arg
                 230                 235                 240

 Gly Glu Arg His Arg Ser Leu Asp Arg Arg Glu Arg Gly Arg Ser
                 245                 250                 255

 Pro Asp Arg Arg Arg Gln Asp Ser Arg Tyr Arg Ser Asp Tyr Asp
                 260                 265                 270

 Arg Gly Arg Thr Pro Ser Arg His Arg Ser Tyr Glu Arg Ser Arg
                 275                 280                 285

 Glu Arg Glu Arg Glu Arg His Arg His Arg Asp Asn Arg Arg Ser
                 290                 295                 300

 Pro Ser Leu Glu Arg Ser Tyr Lys Lys Glu Tyr Lys Arg Ser Gly
                 305                 310                 315

 Arg Ser Tyr Gly Leu Ser Val Val Pro Glu Pro Ala Gly Cys Thr
                 320                 325                 330

 Pro Glu Leu Pro Gly Glu Ile Ile Lys Asn Thr Asp Ser Trp Ala
                 335                 340                 345

 Pro Pro Leu Glu Ile Val Asn His Arg Ser Pro Ser Arg Glu Lys
                 350                 355                 360

 Lys Arg Ala Arg Trp Glu Glu Glu Lys Asp Arg Trp Ser Asp Asn
                 365                 370                 375

 Gln Ser Ser Gly Lys Asp Lys Asn Tyr Thr Ser Ile Lys Glu Lys
                 380                 385                 390

 Glu Pro Glu Glu Thr Met Pro Asp Lys Asn Glu Glu Glu Glu Glu
                 395                 400                 405

 Glu Leu Leu Lys Pro Val Trp Ile Arg Cys Thr His Ser Glu Asn
                 410                 415                 420

 Tyr Tyr Ser Ser Asp Pro Met Asp Gln Val Gly Asp Ser Thr Val
                 425                 430                 435

 Val Gly Thr Ser Arg Leu Arg Asp Leu Tyr Asp Lys Phe Glu Glu
                 440                 445                 450

 Glu Leu Gly Ser Arg Gln Glu Lys Ala Lys Ala Ala Arg Pro Pro
                 455                 460                 465

 Trp Glu Pro Pro Lys Thr Lys Leu Asp Glu Asp Leu Glu Ser Ser
                 470                 475                 480

 Ser Glu Ser Glu Cys Glu Ser Asp Glu Asp Ser Thr Cys Ser Ser
                 485                 490                 495

 Ser Ser Asp Ser Glu Val Phe Asp Val Ile Ala Glu Ile Lys Arg
                 500                 505                 510

 Lys Lys Ala His Pro Asp Arg Leu His Asp Glu Leu Trp Tyr Asn
                 515                 520                 525

 Asp Pro Gly Gln Met Asn Asp Gly Pro Leu Cys Lys Cys Ser Ala
                 530                 535                 540

 Lys Ala Arg Arg Thr Gly Ile Arg His Ser Ile Tyr Pro Gly Glu
                 545                 550                 555

 Glu Ala Ile Lys Pro Cys Arg Pro Met Thr Asn Asn Ala Gly Arg
                 560                 565                 570

 Leu Phe His Tyr Arg Ile Thr Val Ser Pro Pro Thr Asn Phe Leu
                 575                 580                 585

 Thr Asp Arg Pro Thr Val Ile Glu Tyr Asp Asp His Glu Tyr Ile
                 590                 595                 600

 Phe Glu Gly Phe Ser Met Phe Ala His Ala Pro Leu Thr Asn Ile
                 605                 610                 615

 Pro Leu Cys Lys Val Ile Arg Phe Asn Ile Asp Tyr Thr Ile His
                 620                 625                 630

 Phe Ile Glu Glu Met Met Pro Glu Asn Phe Cys Val Lys Gly Leu
                 635                 640                 645

 Glu Leu Phe Ser Leu Phe Leu Phe Arg Asp Ile Leu Glu Leu Tyr
                 650                 655                 660

 Asp Trp Asn Leu Lys Gly Pro Leu Phe Glu Asp Ser Pro Pro Cys
                 665                 670                 675

 Cys Pro Arg Phe His Phe Met Pro Arg Phe Val Arg Phe Leu Pro
                 680                 685                 690

 Asp Gly Gly Lys Glu Val Leu Ser Met His Gln Ile Leu Leu Tyr
                 695                 700                 705

 Leu Leu Arg Cys Ser Lys Ala Leu Val Pro Glu Glu Glu Ile Ala
                 710                 715                 720

 Asn Met Leu Gln Trp Glu Glu Leu Glu Trp Gln Lys Tyr Ala Glu
                 725                 730                 735

 Glu Cys Lys Gly Met Ile Val Thr Asn Pro Gly Thr Lys Pro Ser
                 740                 745                 750

 Ser Val Arg Ile Asp Gln Leu Asp Arg Glu Gln Phe Asn Pro Asp
                 755                 760                 765

 Val Ile Thr Phe Pro Ile Ile Val His Phe Gly Ile Arg Pro Ala
                 770                 775                 780

 Gln Leu Ser Tyr Ala Gly Asp Pro Gln Tyr Gln Lys Leu Trp Lys
                 785                 790                 795

 Ser Tyr Val Lys Leu Arg His Leu Leu Ala Asn Ser Pro Lys Val
                 800                 805                 810

 Lys Gln Thr Asp Lys Gln Lys Leu Ala Gln Arg Glu Glu Ala Leu
                 815                 820                 825

 Gln Lys Ile Arg Gln Lys Asn Thr Met Arg Arg Glu Val Thr Val
                 830                 835                 840

 Glu Leu Ser Ser Gln Gly Phe Trp Lys Thr Gly Ile Arg Ser Asp
                 845                 850                 855

 Val Cys Gln His Ala Met Met Leu Pro Val Leu Thr His His Ile
                 860                 865                 870

 Arg Tyr His Gln Cys Leu Met His Leu Asp Lys Leu Ile Gly Tyr
                 875                 880                 885

 Thr Phe Gln Asp Arg Cys Leu Leu Gln Leu Ala Met Thr His Pro
                 890                 895                 900

 Ser His His Leu Asn Phe Gly Met Asn Pro Asp His Ala Arg Asn
                 905                 910                 915

 Ser Leu Ser Asn Cys Gly Ile Arg Gln Pro Lys Tyr Gly Asp Arg
                 920                 925                 930

 Lys Val His His Met His Met Arg Lys Lys Gly Ile Asn Thr Leu
                 935                 940                 945

 Ile Asn Ile Met Ser Arg Leu Gly Gln Asp Asp Pro Thr Pro Ser
                 950                 955                 960

 Arg Ile Asn His Asn Glu Arg Leu Glu Phe Leu Gly Asp Ala Val
                 965                 970                 975

 Val Glu Phe Leu Thr Ser Val His Leu Tyr Tyr Leu Phe Pro Ser
                 980                 985                 990

 Leu Glu Glu Gly Gly Leu Ala Thr Tyr Arg Thr Ala Ile Val Gln
                 995                1000                1005

 Asn Gln His Leu Ala Met Leu Ala Lys Lys Leu Glu Leu Asp Pro
                1010                1015                1020

 Phe Met Leu Tyr Ala His Gly Pro Asp Leu Cys Arg Glu Ser Asp
                1025                1030                1035

 Leu Arg His Ala Met Ala Asn Cys Phe Glu Ala Leu Ile Gly Ala
                1040                1045                1050

 Val Tyr Leu Glu Gly Ser Leu Glu Glu Ala Lys Gln Leu Phe Gly
                1055                1060                1065

 Arg Leu Leu Phe Asn Asp Pro Asp Leu Arg Glu Val Trp Leu Asn
                1070                1075                1080

 Tyr Pro Leu His Pro Leu Gln Leu Gln Glu Pro Asn Thr Asp Arg
                1085                1090                1095

 Gln Leu Ile Glu Thr Ser Pro Val Leu Gln Lys Leu Thr Glu Phe
                1100                1105                1110

 Glu Glu Ala Ile Gly Val Ile Phe Thr His Val Arg Leu Leu Ala
                1115                1120                1125

 Arg Ala Phe Thr Leu Arg Thr Val Gly Phe Asn His Leu Thr Leu
                1130                1135                1140

 Gly His Asn Gln Arg Met Glu Phe Leu Gly Asp Ser Ile Met Gln
                1145                1150                1155

 Leu Val Ala Thr Glu Tyr Leu Phe Ile His Phe Pro Asp His His
                1160                1165                1170

 Glu Gly His Leu Thr Leu Leu Arg Ser Ser Leu Val Asn Asn Arg
                1175                1180                1185

 Thr Gln Ala Lys Val Ala Glu Glu Leu Gly Met Gln Glu Tyr Ala
                1190                1195                1200

 Ile Thr Asn Asp Lys Thr Lys Arg Pro Val Ala Leu Arg Thr Lys
                1205                1210                1215

 Thr Leu Ala Asp Leu Leu Glu Ser Phe Ile Ala Ala Leu Tyr Thr
                1220                1225                1230

 Asp Lys Asp Leu Glu Tyr Val His Thr Phe Met Asn Val Cys Phe
                1235                1240                1245

 Phe Pro Arg Leu Lys Glu Phe Ile Leu Asn Gln Asp Trp Asn Asp
                1250                1255                1260

 Pro Lys Ser Gln Leu Gln Gln Cys Cys Leu Thr Leu Arg Thr Glu
                1265                1270                1275

 Gly Lys Glu Pro Asp Ile Pro Leu Tyr Lys Thr Leu Gln Thr Val
                1280                1285                1290

 Gly Pro Ser His Ala Arg Thr Tyr Thr Val Ala Val Tyr Phe Lys
                1295                1300                1305

 Gly Glu Arg Ile Gly Cys Gly Lys Gly Pro Ser Ile Gln Gln Ala
                1310                1315                1320

 Glu Met Gly Ala Ala Met Asp Ala Leu Glu Lys Tyr Asn Phe Pro
                1325                1330                1335

 Gln Met Ala His Gln Lys Arg Phe Ile Glu Arg Lys Tyr Arg Gln
                1340                1345                1350

 Glu Leu Lys Glu Met Arg Trp Glu Arg Glu His Gln Glu Arg Glu
                1355                1360                1365

 Pro Asp Glu Thr Glu Asp Ile Lys Lys
                1370

<210> 3193
<211> 1048
<212> DNA
<213> Homo sapien

<400> 3193
 ccccgcacga aaccgagttc tggagaacgc catcagctcg ctgcttaaaa 50

 ttaaaccaca ggttccatta tgggtcgact tgatgggaaa gtcatcatcc 100

 tgacggccgc tgctcagggg attggccaag cagctgcctt agcttttgca 150

 agagaaggtg ccaaagtcat agccacagac attaatgagt ccaaacttca 200

 ggaactggaa aagtacccgg gtattcaaac tcgtgtcctt gatgtcacaa 250

 agaagaaaca aattgatcag tttgccaatg aagttgagag acttgatgtt 300

 ctctttaatg ttgctggttt tgtccatcat ggaactgtcc tggattgtga 350

 ggagaaagac tgggacttct cgatgaatct caatgtgcgc agcatgtacc 400

 tgatgatcaa ggcattcctt cctaaaatgc ttgctcagaa atctggcaat 450

 attatcaaca tgtcttctgt ggcttccagc gtcaaaggag ttgtgaacag 500

 atgtgtgtac agcacaacca aggcagccgt gattggcctc acaaaatctg 550

 tggctgcaga tttcatccag cagggcatca ggtgcaactg tgtgtgccca 600

 ggaacagttg atacgccatc tctacaagaa agaatacaag ccagaggaaa 650

 tcctgaagag gcacggaatg atttcctgaa gagacaaaag acgggaagat 700

 tcgcaactgc agaagaaata gccatgctct gcgtgtattt ggcttctgat 750

 gaatctgctt atgtaactgg taaccctgtc atcattgatg gaggctggag 800

 cttgtgattt taggatctcc atggtgggaa ggaaggcagg cccttcctat 850

 ccacagtgaa cctggttacg aagaaaactc accaatcatc tccttcctgt 900

 taatcacatg ttaatgaaaa taagctcttt ttaatgatgt cactgtttgc 950

 aagagtctga ttctttaagt atattaatct ctttgtaatc tcttctgaaa 1000

 tcattgtaaa gaaataaaaa tattgaactc ataaaaaaaa aaaaaaaa 1048

<210> 3194
<211> 245
<212> PRT
<213> Homo sapien

<400> 3194
 Met Gly Arg Leu Asp Gly Lys Val Ile Ile Leu Thr Ala Ala Ala
   1               5                  10                  15

 Gln Gly Ile Gly Gln Ala Ala Ala Leu Ala Phe Ala Arg Glu Gly
                  20                  25                  30

 Ala Lys Val Ile Ala Thr Asp Ile Asn Glu Ser Lys Leu Gln Glu
                  35                  40                  45

 Leu Glu Lys Tyr Pro Gly Ile Gln Thr Arg Val Leu Asp Val Thr
                  50                  55                  60

 Lys Lys Lys Gln Ile Asp Gln Phe Ala Asn Glu Val Glu Arg Leu
                  65                  70                  75

 Asp Val Leu Phe Asn Val Ala Gly Phe Val His His Gly Thr Val
                  80                  85                  90

 Leu Asp Cys Glu Glu Lys Asp Trp Asp Phe Ser Met Asn Leu Asn
                  95                 100                 105

 Val Arg Ser Met Tyr Leu Met Ile Lys Ala Phe Leu Pro Lys Met
                 110                 115                 120

 Leu Ala Gln Lys Ser Gly Asn Ile Ile Asn Met Ser Ser Val Ala
                 125                 130                 135

 Ser Ser Val Lys Gly Val Val Asn Arg Cys Val Tyr Ser Thr Thr
                 140                 145                 150

 Lys Ala Ala Val Ile Gly Leu Thr Lys Ser Val Ala Ala Asp Phe
                 155                 160                 165

 Ile Gln Gln Gly Ile Arg Cys Asn Cys Val Cys Pro Gly Thr Val
                 170                 175                 180

 Asp Thr Pro Ser Leu Gln Glu Arg Ile Gln Ala Arg Gly Asn Pro
                 185                 190                 195

 Glu Glu Ala Arg Asn Asp Phe Leu Lys Arg Gln Lys Thr Gly Arg
                 200                 205                 210

 Phe Ala Thr Ala Glu Glu Ile Ala Met Leu Cys Val Tyr Leu Ala
                 215                 220                 225

 Ser Asp Glu Ser Ala Tyr Val Thr Gly Asn Pro Val Ile Ile Asp
                 230                 235                 240

 Gly Gly Trp Ser Leu
                 245

<210> 3195
<211> 7136
<212> DNA
<213> Homo sapien

<400> 3195
 gcttatattt tttccagctc ccaaattccc tttattccac tttagtccct 50

 tcattttcag agatgaggaa acagattgct ttgttcaaag acagctagaa 100

 ctagaacaca ggctaatact tgctagccat gtgatatact aatgtcagcc 150

 aaatacgggc atttacactt tcagatgttt gccatatctg tgcacttact 200

 aattctgttt aatacaattt aaattgactc ctttaaataa gcttatttta 250

 aaggaaattt tttgctacta taaatagaaa accattatat cctttaaata 300

 gtaactctaa ataggaattc aaaacaaagc aacgttatta aaatttaatt 350

 taaaattaat ttaaatttaa ttgttattaa atttttaatt attgctgttc 400

 ttcgtcagaa atgtgtcaaa gcattgtttt catgtttgat gtcagttcct 450

 taattgtcta aacagaaaaa gcacagctaa tgcctctagt taagcttctg 500

 tataactttt ttaaatgaaa tgcttcttag aggggaaatg agagggcatg 550

 aatacatgtt tatatactaa agtatgattt catgtatatc agaagatctt 600

 attatatgga accaaaatta ttctttggtt gatttaattg ttcttgaaac 650

 ttcagttttt accttgaagg ttttagttag cttagcataa gtttattttt 700

 ctaaataagg aatctgattg cctcacaact cagatgtatc acagttatgg 750

 tgaaatagca atatattggt ttctgtaacc ttttaaatac cgtaatgaat 800

 taaaatctct tcagcaaaag caaatatatc tagggtgacg agaggtgttt 850

 ttagtgtatt tgaatgatgg aaatgttttt cttaaaatat ttctgaagca 900

 ttttttaaaa taattttttg aatttattga tgatagtagt tgtgtgttag 950

 tgtgaatgac tggtctaaat gtgtatgtca cttccaaggg attagtaggg 1000

 gtcagaatga tttgttttat tcattgactt ttcctttgac gtgttcttat 1050

 tcattgggct acatacattc cctgttgcct tctcaccaaa agtgccacta 1100

 cacaggctgt atttcattgt actgtagaaa aagacaagta gacctttttc 1150

 attcatgaga ttcctatgaa atctgttggt ggaggtataa aatgaggaga 1200

 cttttatggg ctagctagta ggagttttgc tgtgaaacct ttgtaacagg 1250

 tctatcagga actagggaga gaaataaatg caggaaatac ttgatcccat 1300

 taaactgagg atgaaaaaga catgataata ttttggggat tatttattgt 1350

 gtgattttcc ggctgatcag aagtgttaat tttttgttat acttgtgtca 1400

 aatacatata tatatatata ttttgaaatg gagtcttgct ctgtcaccca 1450

 ggctggagtg cagtggtgcg atctgggttc actgcaacct ctgcctccag 1500

 gttcaagtga tcctcctgcc tcagcctccc gagtagctag gactacaggc 1550

 acgtgccacc acgccctgct aatttttgta ttcttagtgg agatggggtt 1600

 tcaccatgtt ggccaggctg gtcttgaact cctgacctca agtgatcttc 1650

 ccaccttggc ctttctgaac tatttccttt acacacattt agaactacat 1700

 ctaactgtat tatagttttc actttcacca tcagacaaaa ttcagaagat 1750

 tcaagagaag gaaagtcgat tgtatttact catatttttg ctaccgtgtt 1800

 tttacatctc atattttaag gctctcttaa ttatttattt tctgtttagt 1850

 taatttcctc tagccattct ttatttatag tgggtctgct ggtaacaaat 1900

 tctctcaatt tttcctcgtc tgagaatgtc ttgacttccc ttccattttt 1950

 gtcagcacct gaaaaatact atgccactat cttctgggtt ctgtggtttc 2000

 tgatgagaac tccactgtca gtctaattgt cgttataaat gcagtgttct 2050

 ctctctctct ctgcttccag gatatttttt cttttttttt tttttttttt 2100

 tcttgagacg gagtctcact ctgtcgccca ggctggagtg cagtggcgca 2150

 attttggctc actgcaagct ctgcctcccg ggttcaagcg attactccca 2200

 ctttagcctc ccaagtagct aggactacaa ggcacaccac catgcctggc 2250

 taatttttgt atttttagta gagacggggt ttcaccatgt tgcccaggct 2300

 ggtctcgaac tcctgacatc aagtgatctt cctgcctccg cttcccaaag 2350

 tgctggaatt acaggcgtga gccactgctc ccagcctctt tattttttca 2400

 gctttactct ttcttctgtc tttttgacat gtgtgtccag tgacacacgt 2450

 gttagatttt gctatagtct cacgcacggg tctataaggc tctgtttttt 2500

 gtttcatttt gtttttccta ttttctctct attcagatcg agtaatttcc 2550

 actgttcagt tttatcatag ctgcttttaa atctttgtca ggtaattctg 2600

 tcatctaagt tttggcacct attgattatc ttttgcattg tttttgtttt 2650

 tgtttctgtt tttgttttga gatggagtct tgctctgttg cccaggttgg 2700

 agtgcagtgg cactgatctc ggctcactgc aacctcctcc tcccgggttc 2750

 aagtggttct cctgcctcaa cctccttagt agctgggatt acaggcatgt 2800

 gccaccacgc ccggctaatt ttgtattttt agtagagacc aggtttatcc 2850

 atgttggtca ggctggtctc aaactcccaa cctcaagtga tccgcctgcc 2900

 tcgacctccc aaagtgctgg gattacaggc gtgaaccact gcacccagcc 2950

 tatcttttgc attgttttaa atcttgttct tgctaggatg aatgattttc 3000

 tgttaaaact agatattttc atattatgtt cctaggctct ggatattatc 3050

 taaaccttct gtttccactg gcttttattg acactgcttt ggcaaggtca 3100

 tagggggtgc ctcattactg ccaggtggac atagaagtca agggtcccta 3150

 ctcagcctct actgatgcct caggaagagg atccttcttg ttattgctgg 3200

 gtgggggtgg aagtctagct gacacctact gaggtaggtg ctggggcatg 3250

 cccggccatc agggtgaaag tcctggctcc ctagttggcc tacttttaca 3300

 ttgccctaat agggcattgg agctcctcac tatggtttat gagctggaag 3350

 tcaaggctcc tcacttagct ttcgttggtg tgggtggtgg tggggcaaaa 3400

 ctgttttctg ggtttggctg gagtggagca gttactgtca aaagttttct 3450

 gtcttgccag gctgtccctt tcttgtttct ttggctagag agagcaagct 3500

 tttgttgtgg ctctttttgt ctgtgccagt tggcatttcc aggttgctgc 3550

 cttctttagc tccaagtctg ggatatatta ggcaaaaaga aaacccagag 3600

 aatttacacc accgtgtcat tccatgggtc ctgaggtccc ttacttagtc 3650

 tgccttctct ccacttttca cagtcttctc atgttttgta tataatgtcc 3700

 agggtcttta gttatactta gcagaaataa aagggaaaag tatgtctgct 3750

 ctatgcttct gtaagtggaa gtcttcaaat ttgcattttt gattccttta 3800

 aacagttttg taaaatatat aatcattatt gggcaaaatg tcccataaaa 3850

 tgtatatacc ttgtgatggt ttgcataata ttgtgttcaa gaggactgct 3900

 gaaaaataac atctttattt aaactgaaac gaattgttca cattattaat 3950

 gaaaactttt cccctctagg aaataatgca aaaggtgtcc caaggctcct 4000

 gaccagtgaa caaagatttg agaaagacag ccaagctcat gttttctcct 4050

 gatcaagaaa atcatccatc taaagcacca gtaaaatatg gtgaactcat 4100

 tgtcttaggc tataatgggt ctctcccaaa tggcgataga ggaaggagga 4150

 aaagtaggtt tgctttgttt aaaagaccta aggcaaatgg ggtgaagccc 4200

 agcactgtgc atattgcttg tactcctcag gctgcaaagg caataagcaa 4250

 caaagaccag catagcatat catatacttt gtctcgggcc cagactgtgg 4300

 tggttgaata tactcatgac agcaacacag atatgtttca gattggccgg 4350

 tcgactgaaa gccccattga ttttgtagta actgacacgg ttcctggaag 4400

 tcaaagtaat tctgatacac agtcagtaca aagcactata tcaagatttg 4450

 cctgcagaat catatgtgaa cggaatcctc cctttacagc acggatttat 4500

 gctgcaggat ttgactcatc aaaaaacatc tttcttgggg agaaggctgc 4550

 caaatggaag acatcagatg gacagatgga tggcttgacc actaatggtg 4600

 ttcttgtgat gcatccacgc aatgggttca cagaagactc caagcctgga 4650

 atatggagag aaatatcggt gtgtggaaat gtatttagcc tacgtgaaac 4700

 cagatcggct cagcagagag gaaaaatggt ggaaattgaa accaatcagt 4750

 tacaagatgg ctcgttaatt gacctctgtg gtgcaacatt gttatggcgt 4800

 actgcagaag gcctttccca cactcctacc gtgaagcatt tagaagcttt 4850

 aagacaggaa atcaatgcag cacgacctca gtgccctgta gggttcaaca 4900

 cactagcatt tcctagtatg aagaggaaag acgttgtaga tgaaaaacaa 4950

 ccatgggtat atctaaactg cggccatgta catggctatc ataactgggg 5000

 aaacaaagaa gaacgtgatg gaaaagatcg tgaatgtcct atgtgtaggt 5050

 ctgttggtcc ctatgttcct ctgtggcttg gatgtgaagc tggattttat 5100

 gtggacgccg gccctccaac ccatgcgttt agcccgtgtg ggcatgtgtg 5150

 ttcagaaaag acaactgcct attggtccca gatcccactt cctcatggta 5200

 ctcatacttt tcatgcagcc tgtccctttt gtgcacatca gttggctggt 5250

 gaacaaggct acatcagact tatttttcaa ggacctctag actaacagac 5300

 cattgtcttg caggactaca ttataaattt ataagctaag tgagttgggt 5350

 tttcgaacct gttgtccacg tcacagtttt tctgctctgg tcatttgcat 5400

 taagatgaag aattttttaa aacatttata ataaatagta gcaatttctg 5450

 agcaaaaatc tgggaaactc aagcaaagga atttctgaaa gtatcagtct 5500

 tctgaattct gagttttgaa aatatatttt gaggagaaaa agacatagtc 5550

 taatttgatg ccttcctttt agtgtttttg aatcacctat cctcagtgct 5600

 gaaattgttt tgtataactg agggtactgt tggttcaaac tatgttagtt 5650

 tacagtttgt tgcaaacatt gtaaaataca gcgacatgta tattaacttt 5700

 tttctattta tctttattat agaaaatacc ttagaatgtt cttgatagag 5750

 tagcatggta acgatggtgt cacacccttg gtgtgaatgg tagcttagtg 5800

 agcaacctag ctcaaggatt tgcaaagtta ggaagaagga cgagagagcc 5850

 tctctcccca ccccaatcta aatatggaat ttggtaaatt agaatacttt 5900

 gtaatttgta agaccaaatt catactaatt acccgcgtga aaggtgtttg 5950

 tttttaacaa cattgaagat aatcaggaaa gattttttct taatgtttct 6000

 ctcgagcgta gtactataac aaaaacttaa tgctaagaaa cattttatat 6050

 gctcctttgg atatgcaatt taatctagat tatctatttt tctcccatga 6100

 taactaatct gtttttagta tcagcagcat ttggcaagtt tattttttgg 6150

 atataaactg tggttcatct gttcactgtt tctagaaaaa aatcattgcc 6200

 ataagaaaaa gtataaatta gcaagaaagg agagtgactt gatttgcttt 6250

 tggaaaaaga aatgcttaat taattattct gtatttggcc ttattcgggc 6300

 attaggaaat ctagagatct aaagggttga atgacaatag tgcccccgtt 6350

 tttagcagac cagccttaac tctgggtttg aatcctaagg agattgccac 6400

 agtgagactt aaggaaatgt ttggttggca gatgagcacc aatgactgca 6450

 gcgtggagtg acgcactgca tggtctgttt attctctaat tccaatatgt 6500

 cttttgcttc cagaagcaag aaaagtttct tctctcccct ccttcccacc 6550

 cttttttcaa aggcaccaca agtatagaca gttgcactac atcaaatctt 6600

 tttttgacac ttgtagaaac cagtacactt ttagattaga cagtatcttc 6650

 ttttaatatt ttgatttgtt ttcctttagt ttgaaaagtt gtataatact 6700

 taactgactg tagcaaagtt ttatatgtgg tagcatacct ttaatttatc 6750

 ctattacaaa actgttctga attttctttt ggtttttaaa aaacaaaact 6800

 tgttgcttag aagccatgaa ttattttatt ttacttcaac tgtcgaaact 6850

 tccttgtttt aaaaaatgat catttgggtt cactcaggaa atgcatgtca 6900

 ggaaacttgt attataagtt tattagttgt gatgtatcag taactgctgt 6950

 tacccctttt tcaaagaaat gtaattgatt ttgaagtttt ctagattgtc 7000

 acatgctttg tgactaatgc aagaaagcaa gtcctgtgtt gtatttgttc 7050

 tagtcatttt tattcaggct atatattgta gcttaatttt tatttgcaat 7100

 taatttattt aaactaagta aatacttttc aaaata 7136

<210> 3196
<211> 418
<212> PRT
<213> Homo sapien

<400> 3196
 Met Phe Ser Pro Asp Gln Glu Asn His Pro Ser Lys Ala Pro Val
   1               5                  10                  15

 Lys Tyr Gly Glu Leu Ile Val Leu Gly Tyr Asn Gly Ser Leu Pro
                  20                  25                  30

 Asn Gly Asp Arg Gly Arg Arg Lys Ser Arg Phe Ala Leu Phe Lys
                  35                  40                  45

 Arg Pro Lys Ala Asn Gly Val Lys Pro Ser Thr Val His Ile Ala
                  50                  55                  60

 Cys Thr Pro Gln Ala Ala Lys Ala Ile Ser Asn Lys Asp Gln His
                  65                  70                  75

 Ser Ile Ser Tyr Thr Leu Ser Arg Ala Gln Thr Val Val Val Glu
                  80                  85                  90

 Tyr Thr His Asp Ser Asn Thr Asp Met Phe Gln Ile Gly Arg Ser
                  95                 100                 105

 Thr Glu Ser Pro Ile Asp Phe Val Val Thr Asp Thr Val Pro Gly
                 110                 115                 120

 Ser Gln Ser Asn Ser Asp Thr Gln Ser Val Gln Ser Thr Ile Ser
                 125                 130                 135

 Arg Phe Ala Cys Arg Ile Ile Cys Glu Arg Asn Pro Pro Phe Thr
                 140                 145                 150

 Ala Arg Ile Tyr Ala Ala Gly Phe Asp Ser Ser Lys Asn Ile Phe
                 155                 160                 165

 Leu Gly Glu Lys Ala Ala Lys Trp Lys Thr Ser Asp Gly Gln Met
                 170                 175                 180

 Asp Gly Leu Thr Thr Asn Gly Val Leu Val Met His Pro Arg Asn
                 185                 190                 195

 Gly Phe Thr Glu Asp Ser Lys Pro Gly Ile Trp Arg Glu Ile Ser
                 200                 205                 210

 Val Cys Gly Asn Val Phe Ser Leu Arg Glu Thr Arg Ser Ala Gln
                 215                 220                 225

 Gln Arg Gly Lys Met Val Glu Ile Glu Thr Asn Gln Leu Gln Asp
                 230                 235                 240

 Gly Ser Leu Ile Asp Leu Cys Gly Ala Thr Leu Leu Trp Arg Thr
                 245                 250                 255

 Ala Glu Gly Leu Ser His Thr Pro Thr Val Lys His Leu Glu Ala
                 260                 265                 270

 Leu Arg Gln Glu Ile Asn Ala Ala Arg Pro Gln Cys Pro Val Gly
                 275                 280                 285

 Phe Asn Thr Leu Ala Phe Pro Ser Met Lys Arg Lys Asp Val Val
                 290                 295                 300

 Asp Glu Lys Gln Pro Trp Val Tyr Leu Asn Cys Gly His Val His
                 305                 310                 315

 Gly Tyr His Asn Trp Gly Asn Lys Glu Glu Arg Asp Gly Lys Asp
                 320                 325                 330

 Arg Glu Cys Pro Met Cys Arg Ser Val Gly Pro Tyr Val Pro Leu
                 335                 340                 345

 Trp Leu Gly Cys Glu Ala Gly Phe Tyr Val Asp Ala Gly Pro Pro
                 350                 355                 360

 Thr His Ala Phe Ser Pro Cys Gly His Val Cys Ser Glu Lys Thr
                 365                 370                 375

 Thr Ala Tyr Trp Ser Gln Ile Pro Leu Pro His Gly Thr His Thr
                 380                 385                 390

 Phe His Ala Ala Cys Pro Phe Cys Ala His Gln Leu Ala Gly Glu
                 395                 400                 405

 Gln Gly Tyr Ile Arg Leu Ile Phe Gln Gly Pro Leu Asp
                 410                 415

<210> 3197
<211> 644
<212> DNA
<213> Homo sapien

<400> 3197
 gctccctggg gaacccagca ggcggcgaag atggcggaga acagcggtcg 50

 cgccggcaag agcagcggga gcggcgcggg gaagggggcg gtgtccgcag 100

 agcaggtgat tgctggcttc aaccgccttc ggcaggaaca gcgaggcctg 150

 gcatccaaag cagctgagtt ggagatggag ttgaatgagc acagcctagt 200

 gatcgataca ctgaaggagg tagatgaaac tcgtaagtgc taccgcatgg 250

 ttggaggagt gctggtggag cgaactgtca aagaggtgct gcccgctttg 300

 gagaacaaca aggagcagat acagaagatc attgagacac tgacacagca 350

 gcttcaggca aagggaaaag aactaaatga attccgggaa aagcacaaca 400

 ttcgtctcat gggagaagat gagaagccag cagccaagga aaactcagaa 450

 ggggctgggg ctaaggccag ctcagctgga gtgttggtct cctagggacc 500

 aaggcctttg catttttttc taccctgact cccacttcta atttctcttt 550

 attgttatta ttattatttt ctctgctatt gtaatatttt tttgttaatt 600

 aaatgttttg gtcagaatct taaaaaaaaa aaaaaaaaaa aaaa 644

<210> 3198
<211> 154
<212> PRT
<213> Homo sapien

<400> 3198
 Met Ala Glu Asn Ser Gly Arg Ala Gly Lys Ser Ser Gly Ser Gly
   1               5                  10                  15

 Ala Gly Lys Gly Ala Val Ser Ala Glu Gln Val Ile Ala Gly Phe
                  20                  25                  30

 Asn Arg Leu Arg Gln Glu Gln Arg Gly Leu Ala Ser Lys Ala Ala
                  35                  40                  45

 Glu Leu Glu Met Glu Leu Asn Glu His Ser Leu Val Ile Asp Thr
                  50                  55                  60

 Leu Lys Glu Val Asp Glu Thr Arg Lys Cys Tyr Arg Met Val Gly
                  65                  70                  75

 Gly Val Leu Val Glu Arg Thr Val Lys Glu Val Leu Pro Ala Leu
                  80                  85                  90

 Glu Asn Asn Lys Glu Gln Ile Gln Lys Ile Ile Glu Thr Leu Thr
                  95                 100                 105

 Gln Gln Leu Gln Ala Lys Gly Lys Glu Leu Asn Glu Phe Arg Glu
                 110                 115                 120

 Lys His Asn Ile Arg Leu Met Gly Glu Asp Glu Lys Pro Ala Ala
                 125                 130                 135

 Lys Glu Asn Ser Glu Gly Ala Gly Ala Lys Ala Ser Ser Ala Gly
                 140                 145                 150

 Val Leu Val Ser


<210> 3199
<211> 5214
<212> DNA
<213> Homo sapien

<400> 3199
 gcggccgcgc caccgccgga gagggaggcc cgagcgcagg agcctctggt 50

 ggatgggtgc agcggcggcg ggaggacgcg gaagaggagc cccgggggta 100

 gcggcggcgc gagcaggggc gcggggaccg ggctgtctga ggtgcgcgcc 150

 gcgctggggc tcgcgctcta cctgatcgcg ctgcggacgc tggtgcagct 200

 ctcgctgcag cagctcgtgc tacgcggggc cgctggacac cgcggggagt 250

 tcgacgcgct ccaagccagg gattatcttg aacacataac ctccattggc 300

 cccaggacta caggaagtcc agaaaatgaa attctgaccg tgcactacct 350

 tttggaacag attaaactga ttgaagtgca aagcaacagc cttcataaga 400

 tttcagtaga tgtacaacgg cccacaggct cttttagcat tgatttcttg 450

 ggaggtttta caagctatta tgacaacatc accaatgttg tggtaaagct 500

 ggaacccaga gatggagccc agcatgctgt cttggctaat tgtcattttg 550

 actcagtagc aaactcacca ggtgccagtg atgatgcagt tagctgctca 600

 gtgatgctgg aagtccttcg cgtcttgtca acatcttcag aagccttgca 650

 tcatgctgtc atatttctct ttaatggtgc tgaggaaaat gtcttgcaag 700

 ccagtcatgg tttcattact cagcacccct gggctagctt gattcgtgca 750

 ttcattaacc tagaggcagc aggtgtagga gggaaagaac ttgtattcca 800

 aacaggtcct gaaaatcctt ggttggttca agcttatgtt tcagcagcta 850

 aacacccttt tgcttctgtg gtggctcagg aggtttttca gagtggaatc 900

 attccttcag atactgactt tcgtatctac agggattttg ggaacattcc 950

 aggaatagac ttagctttta ttgagaatgg atacatttat cacaccaagt 1000

 atgacacagc ggacagaatt ctaacagatt ccattcagag agcaggtgac 1050

 aacattttag cagttcttaa gcatctagct acatctgata tgctggctgc 1100

 tgcttctaag tatcgacatg gaaacatggt cttctttgat gtgctgggcc 1150

 tgtttgtcat tgcctacccc tctcgtattg gctcaatcat aaactacatg 1200

 gtggtaatgg gtgttgtttt gtacctgggc aaaaaatttt tgcagcccaa 1250

 acataagact ggtaactaca agaaggactt cttgtgtgga cttggcatca 1300

 ctttgatcag ctggttcact agccttgtta ccgttctcat tatagcagtg 1350

 ttcatctctc ttattggaca gtctctctca tggtataacc acttctatgt 1400

 ctccgtttgt ctgtatggaa ctgcaactgt agccaaaata atacttatac 1450

 atactcttgc gaaaagattt tattacatga atgccagtgc ccagtatctg 1500

 ggagaagtat tttttgacat ttcgctgttt gtccattgct gttttcttgt 1550

 taccctcact taccaaggac tttgctcggc gtttattagt gctgtctggg 1600

 tagcattccc attgctcaca aagctctgtg tgcataagga cttcaagcag 1650

 catggtgccc aaggaaaatt tattgctttt taccttttgg ggatgtttat 1700

 tccttatctt tatgcattgt acctcatctg ggcagtattt gagatgttta 1750

 cccctatcct cgggagaagt ggttctgaaa tcccacctga tgttgtgctg 1800

 gcatccattt tggctggctg tacaatgatt ctctcgtcct attttattaa 1850

 cttcatctac cttgccaaga gcacaaaaaa aaccatgcta actttaactt 1900

 tggtatgtgc aattacattc ctccttgttt gcagtggaac attttttcca 1950

 tatagctcca atcctgctaa tccgaagcca aagagagtgt ttcttcagca 2000

 tatgactaga acattccatg acttggaagg aaatgcagtt aaacgggact 2050

 ctggaatatg gatcaatggg tttgattata ctggaatttc tcacataacc 2100

 cctcacattc ctgagatcaa tgatagtatc cgagctcact gtgaggagaa 2150

 tgcacctctt tgtggttttc cttggtatct tccagtgcac tttctgatca 2200

 ggaaaaactg gtatcttcct gccccagaag tttctccaag aaatcctcct 2250

 catttccgac tcatatccaa agaacagaca ccttgggatt ctataaaatt 2300

 gacttttgaa gcaacaggac caagccatat gtccttctat gttcgagccc 2350

 acaaagggtc aacactttct cagtggtctc ttggcaatgg caccccagtc 2400

 acaagtaaag gaggagacta ctttgtcttt tactcccatg gactccaggc 2450

 ctctgcatgg cagttctgga tagaagtgca ggtttcagaa gaacatcctg 2500

 aaggaatggt caccgtggcc attgctgccc actatctgtc tggggaagac 2550

 aagagatccc ctcaactgga tgctctgaag gaaaagttcc cagattggac 2600

 atttccctct gcctgggtgt gcacctacga tctctttgta ttttaatctt 2650

 gtggatgagc tctaagtaca tgcccagtgg atactccatg tgacatggtt 2700

 tatccctatg ttacgtggat gtttgtaacg taagtcaatg aattttaatg 2750

 atcatatgtt caaagagctt tctgggttaa cgcttttcag ggccaagcac 2800

 tataagggtt tagctgtggc gcagtgatgc atggcctgtt gacacttgaa 2850

 aatgccagtc ttttggcact tcagcacatg tgggtactgc cactacacac 2900

 acgtcatttt atatgacctt aaggacaaag ccaacaatcc acttcaatag 2950

 ctgccccttt aggatcaaga aagatgtaca ctgtcagagc attgttaatg 3000

 agacaaaagt tgtttccaat ttaagcccca aaaccatttg ttgtattagt 3050

 ggatggtggg taaaatatca ttcactgagg taatgattcc ccttgagaat 3100

 ataactctgt gtaggtcact ggaaagtgat tgccataggg ctgggagaga 3150

 agcattgcac tcttgaggct gtagcctgtg tcaagctgtt tcttcaggca 3200

 gcctctcaaa tgtgctttgt ctctctgtgc tgaggcctgg accctgtgct 3250

 gagctggtga ctcactgtcc tgacaagtgg acacacagat gcactgctgt 3300

 gctgctttcc tgaggtggtt ttctatgcct gttttcctct gaaacatgtc 3350

 tgttacccct ctccatctta ccaagttgaa aaggggaata tttggccaca 3400

 tacccctctg gttttcgtag gttcttttgg ttcagaatat tgtttgtgcc 3450

 agtacatgac cttaacttcc ttcctcagag cactgagctg ccatctgggc 3500

 tattctgggg tagaaggaag gctgggagtg gtgggaattt tataaatatt 3550

 tattctcttt tctttgtttc ataggagtct tgtgttatac aaggttagtc 3600

 cttcatggta taatcttact gatgcactgg gcctatcttt ttgttttcca 3650

 gccagttgaa tagattagtt tttctcagta acttactatc cagcagactg 3700

 gctttcctga gacttgaggt tgtggcttat actggaatga gaccactgta 3750

 cgtgtaggtg gttcagatcc tgcgtaatgg cagcatgagg acttaaaagg 3800

 tggttttcat tttgaagatg gctatgtagc ttgtaaggtg tatcacagca 3850

 gtacctctca tggctttttg gttccagcag tgagggcatt ggtgagatca 3900

 atggtaaact gtgcaagctt tctttttatc attaggaaat gtgaaacgtt 3950

 ggacaaattt tgagttttaa caaggacaaa aagttgaaag aaaaggcaca 4000

 gttaaaaaag ggtggctaga tttatcttgg gtgatggagg aaatgagaga 4050

 ggaatgctct tgaaaggtgg tctgtggatc tgtctgaata gaaagagcac 4100

 agtaagtatg cattgccgga gaaaacgtcc ttgaagctgc ttgtctcatg 4150

 tgtatgatgt gctttttaaa tcatgcccct cgttgcctgc ctaatctgtg 4200

 actccctaaa aactaactgg gcccatgtag atggggctgc aaccagagct 4250

 gaataacatg ttaggctcac acatgcatca gcactgcaca ctggaatcat 4300

 tgctcttcct ggactttgta gaaatcagtc tcaagtgctt caagagtctg 4350

 gctcctgcta cttttatctg tcaggtagca cataaggttt gcagggttta 4400

 tattttgtat agaatcacag ttgtggagaa aaagtaataa tttctcaatg 4450

 aattttaaaa atgggcctat tttctatccc cgtggttcat ctgatataat 4500

 tagtgttccc tgtgaattcc ccccctctat gggaaggatg cctttactct 4550

 ttatcagtaa taaattatga ctgttttcat attgccttag ggttatttcc 4600

 ctgtgtaaac cattgtcttt tgttttggtt ttctttagca ttatgaagct 4650

 ttggtattgt acaaggtcag tagtaagatg ctcactagtc tcagggcttg 4700

 tgtaatattc tgggaggtca tttaaatgcc agaaatggtc aagcaattat 4750

 acacagtatt tatgactctg ttaagcatac cgtttgtctg tcacattagt 4800

 agattctgag attaaaaaaa atttttaaag agtgatcatt taaataattt 4850

 ctaaaagggt cttttcaagc tctaacaaag tcactaacaa atgcattatt 4900

 ttctacagaa ttagatgtta gtagtacagt actgcatatt cagggaaaaa 4950

 gtgtgaggaa ttgatttcaa aatagttcgt tcttgtgttt gacctaagaa 5000

 tgattgtcgc atgaagtgtt tgtttttaca gtttagcata tataaacaaa 5050

 catgatagga ttccttaaga tgttaccacc cagggggcca caagccagcc 5100

 tgctgtctca ggaagctgta gaaggagtgt ttgtcaattt cttgtcactg 5150

 gtttgctgac ttactgagga ttaattgttg ccttacaatg ttactgaaat 5200

 aaactgttta atat 5214

<210> 3200
<211> 881
<212> PRT
<213> Homo sapien

<400> 3200
 Ala Ala Ala Pro Pro Pro Glu Arg Glu Ala Arg Ala Gln Glu Pro
   1               5                  10                  15

 Leu Val Asp Gly Cys Ser Gly Gly Gly Arg Thr Arg Lys Arg Ser
                  20                  25                  30

 Pro Gly Gly Ser Gly Gly Ala Ser Arg Gly Ala Gly Thr Gly Leu
                  35                  40                  45

 Ser Glu Val Arg Ala Ala Leu Gly Leu Ala Leu Tyr Leu Ile Ala
                  50                  55                  60

 Leu Arg Thr Leu Val Gln Leu Ser Leu Gln Gln Leu Val Leu Arg
                  65                  70                  75

 Gly Ala Ala Gly His Arg Gly Glu Phe Asp Ala Leu Gln Ala Arg
                  80                  85                  90

 Asp Tyr Leu Glu His Ile Thr Ser Ile Gly Pro Arg Thr Thr Gly
                  95                 100                 105

 Ser Pro Glu Asn Glu Ile Leu Thr Val His Tyr Leu Leu Glu Gln
                 110                 115                 120

 Ile Lys Leu Ile Glu Val Gln Ser Asn Ser Leu His Lys Ile Ser
                 125                 130                 135

 Val Asp Val Gln Arg Pro Thr Gly Ser Phe Ser Ile Asp Phe Leu
                 140                 145                 150

 Gly Gly Phe Thr Ser Tyr Tyr Asp Asn Ile Thr Asn Val Val Val
                 155                 160                 165

 Lys Leu Glu Pro Arg Asp Gly Ala Gln His Ala Val Leu Ala Asn
                 170                 175                 180

 Cys His Phe Asp Ser Val Ala Asn Ser Pro Gly Ala Ser Asp Asp
                 185                 190                 195

 Ala Val Ser Cys Ser Val Met Leu Glu Val Leu Arg Val Leu Ser
                 200                 205                 210

 Thr Ser Ser Glu Ala Leu His His Ala Val Ile Phe Leu Phe Asn
                 215                 220                 225

 Gly Ala Glu Glu Asn Val Leu Gln Ala Ser His Gly Phe Ile Thr
                 230                 235                 240

 Gln His Pro Trp Ala Ser Leu Ile Arg Ala Phe Ile Asn Leu Glu
                 245                 250                 255

 Ala Ala Gly Val Gly Gly Lys Glu Leu Val Phe Gln Thr Gly Pro
                 260                 265                 270

 Glu Asn Pro Trp Leu Val Gln Ala Tyr Val Ser Ala Ala Lys His
                 275                 280                 285

 Pro Phe Ala Ser Val Val Ala Gln Glu Val Phe Gln Ser Gly Ile
                 290                 295                 300

 Ile Pro Ser Asp Thr Asp Phe Arg Ile Tyr Arg Asp Phe Gly Asn
                 305                 310                 315

 Ile Pro Gly Ile Asp Leu Ala Phe Ile Glu Asn Gly Tyr Ile Tyr
                 320                 325                 330

 His Thr Lys Tyr Asp Thr Ala Asp Arg Ile Leu Thr Asp Ser Ile
                 335                 340                 345

 Gln Arg Ala Gly Asp Asn Ile Leu Ala Val Leu Lys His Leu Ala
                 350                 355                 360

 Thr Ser Asp Met Leu Ala Ala Ala Ser Lys Tyr Arg His Gly Asn
                 365                 370                 375

 Met Val Phe Phe Asp Val Leu Gly Leu Phe Val Ile Ala Tyr Pro
                 380                 385                 390

 Ser Arg Ile Gly Ser Ile Ile Asn Tyr Met Val Val Met Gly Val
                 395                 400                 405

 Val Leu Tyr Leu Gly Lys Lys Phe Leu Gln Pro Lys His Lys Thr
                 410                 415                 420

 Gly Asn Tyr Lys Lys Asp Phe Leu Cys Gly Leu Gly Ile Thr Leu
                 425                 430                 435

 Ile Ser Trp Phe Thr Ser Leu Val Thr Val Leu Ile Ile Ala Val
                 440                 445                 450

 Phe Ile Ser Leu Ile Gly Gln Ser Leu Ser Trp Tyr Asn His Phe
                 455                 460                 465

 Tyr Val Ser Val Cys Leu Tyr Gly Thr Ala Thr Val Ala Lys Ile
                 470                 475                 480

 Ile Leu Ile His Thr Leu Ala Lys Arg Phe Tyr Tyr Met Asn Ala
                 485                 490                 495

 Ser Ala Gln Tyr Leu Gly Glu Val Phe Phe Asp Ile Ser Leu Phe
                 500                 505                 510

 Val His Cys Cys Phe Leu Val Thr Leu Thr Tyr Gln Gly Leu Cys
                 515                 520                 525

 Ser Ala Phe Ile Ser Ala Val Trp Val Ala Phe Pro Leu Leu Thr
                 530                 535                 540

 Lys Leu Cys Val His Lys Asp Phe Lys Gln His Gly Ala Gln Gly
                 545                 550                 555

 Lys Phe Ile Ala Phe Tyr Leu Leu Gly Met Phe Ile Pro Tyr Leu
                 560                 565                 570

 Tyr Ala Leu Tyr Leu Ile Trp Ala Val Phe Glu Met Phe Thr Pro
                 575                 580                 585

 Ile Leu Gly Arg Ser Gly Ser Glu Ile Pro Pro Asp Val Val Leu
                 590                 595                 600

 Ala Ser Ile Leu Ala Gly Cys Thr Met Ile Leu Ser Ser Tyr Phe
                 605                 610                 615

 Ile Asn Phe Ile Tyr Leu Ala Lys Ser Thr Lys Lys Thr Met Leu
                 620                 625                 630

 Thr Leu Thr Leu Val Cys Ala Ile Thr Phe Leu Leu Val Cys Ser
                 635                 640                 645

 Gly Thr Phe Phe Pro Tyr Ser Ser Asn Pro Ala Asn Pro Lys Pro
                 650                 655                 660

 Lys Arg Val Phe Leu Gln His Met Thr Arg Thr Phe His Asp Leu
                 665                 670                 675

 Glu Gly Asn Ala Val Lys Arg Asp Ser Gly Ile Trp Ile Asn Gly
                 680                 685                 690

 Phe Asp Tyr Thr Gly Ile Ser His Ile Thr Pro His Ile Pro Glu
                 695                 700                 705

 Ile Asn Asp Ser Ile Arg Ala His Cys Glu Glu Asn Ala Pro Leu
                 710                 715                 720

 Cys Gly Phe Pro Trp Tyr Leu Pro Val His Phe Leu Ile Arg Lys
                 725                 730                 735

 Asn Trp Tyr Leu Pro Ala Pro Glu Val Ser Pro Arg Asn Pro Pro
                 740                 745                 750

 His Phe Arg Leu Ile Ser Lys Glu Gln Thr Pro Trp Asp Ser Ile
                 755                 760                 765

 Lys Leu Thr Phe Glu Ala Thr Gly Pro Ser His Met Ser Phe Tyr
                 770                 775                 780

 Val Arg Ala His Lys Gly Ser Thr Leu Ser Gln Trp Ser Leu Gly
                 785                 790                 795

 Asn Gly Thr Pro Val Thr Ser Lys Gly Gly Asp Tyr Phe Val Phe
                 800                 805                 810

 Tyr Ser His Gly Leu Gln Ala Ser Ala Trp Gln Phe Trp Ile Glu
                 815                 820                 825

 Val Gln Val Ser Glu Glu His Pro Glu Gly Met Val Thr Val Ala
                 830                 835                 840

 Ile Ala Ala His Tyr Leu Ser Gly Glu Asp Lys Arg Ser Pro Gln
                 845                 850                 855

 Leu Asp Ala Leu Lys Glu Lys Phe Pro Asp Trp Thr Phe Pro Ser
                 860                 865                 870

 Ala Trp Val Cys Thr Tyr Asp Leu Phe Val Phe
                 875                 880

<210> 3201
<211> 1224
<212> DNA
<213> Homo sapien

<400> 3201
 gttcggagcg ggcgagcgga gttagcaggg ctttactgca gagcgcgccg 50

 ggcactccag cgaccgtggg gatcagcgta ggtgagctgt ggccttttgc 100

 gaggtgctgc agccatagct acgtgcgttc gctacgagga ttgagcgtct 150

 ccacccagta agtgggcaag aggcggcagg aagtgggtac gcaggggcgc 200

 aaggcgcaca gcctctagac gactcgcttt ccctccggcc aacctctgaa 250

 gccgcgtcct actttgacag ctgcagggcc gcggcctggt cttctgtgct 300

 tcaccatcta cataatgaat cccagtatga agcagaaaca agaagaaatc 350

 aaagagaata taaagaatag ttctgtccca agaagaactc tgaagatgat 400

 tcagccttct gcatctggat ctcttgttgg aagagaaaat gagctgtccg 450

 caggcttgtc caaaaggaaa catcggaatg accacttaac atctacaact 500

 tccagccctg gggttattgt cccagaatct agtgaaaata aaaatcttgg 550

 aggagtcacc caggagtcat ttgatcttat gattaaagaa aatccatcct 600

 ctcagtattg gaaggaagtg gcagaaaaac ggagaaaggc gctgtatgaa 650

 gcacttaagg aaaatgagaa acttcataaa gaaattgaac aaaaggacaa 700

 tgaaattgcc cgcctgaaaa aggagaataa agaactggca gaagtagcag 750

 aacatgtaca gtatatggca gagctaatag agagactgaa tggtgaacct 800

 ctggataatt ttgaatcact ggataatcag gaatttgatt ctgaagaaga 850

 aactgttgag gattctctag tggaagactc agaaattggc acgtgtgctg 900

 aaggaactgt atcttcctct acggatgcaa agccatgtat atgaaatgca 950

 ttaatatttg actgttgaga attttactgc cgaagtttac ctccactagt 1000

 tctttgtagc agagtacata actacataat gccaactctg gaatcaaatt 1050

 tccttgtttg aatcctggga ccctattgca ttaaagtaca aatactatgt 1100

 atttttaatc tatgatggtt tatgtgaata ggattttctc agttgtcagc 1150

 catgacttat gtttattact aaataaactt caaactcctg tggaaaaaaa 1200

 aaaaaaaaaa aaaaaaaaaa aaaa 1224

<210> 3202
<211> 209
<212> PRT
<213> Homo sapien

<400> 3202
 Met Asn Pro Ser Met Lys Gln Lys Gln Glu Glu Ile Lys Glu Asn
   1               5                  10                  15

 Ile Lys Asn Ser Ser Val Pro Arg Arg Thr Leu Lys Met Ile Gln
                  20                  25                  30

 Pro Ser Ala Ser Gly Ser Leu Val Gly Arg Glu Asn Glu Leu Ser
                  35                  40                  45

 Ala Gly Leu Ser Lys Arg Lys His Arg Asn Asp His Leu Thr Ser
                  50                  55                  60

 Thr Thr Ser Ser Pro Gly Val Ile Val Pro Glu Ser Ser Glu Asn
                  65                  70                  75

 Lys Asn Leu Gly Gly Val Thr Gln Glu Ser Phe Asp Leu Met Ile
                  80                  85                  90

 Lys Glu Asn Pro Ser Ser Gln Tyr Trp Lys Glu Val Ala Glu Lys
                  95                 100                 105

 Arg Arg Lys Ala Leu Tyr Glu Ala Leu Lys Glu Asn Glu Lys Leu
                 110                 115                 120

 His Lys Glu Ile Glu Gln Lys Asp Asn Glu Ile Ala Arg Leu Lys
                 125                 130                 135

 Lys Glu Asn Lys Glu Leu Ala Glu Val Ala Glu His Val Gln Tyr
                 140                 145                 150

 Met Ala Glu Leu Ile Glu Arg Leu Asn Gly Glu Pro Leu Asp Asn
                 155                 160                 165

 Phe Glu Ser Leu Asp Asn Gln Glu Phe Asp Ser Glu Glu Glu Thr
                 170                 175                 180

 Val Glu Asp Ser Leu Val Glu Asp Ser Glu Ile Gly Thr Cys Ala
                 185                 190                 195

 Glu Gly Thr Val Ser Ser Ser Thr Asp Ala Lys Pro Cys Ile
                 200                 205

<210> 3203
<211> 4348
<212> DNA
<213> Homo sapien

<400> 3203
 gggaggccca gggagaacgg ggaagggaca tttagtttga gacggtgctg 50

 agataggatc atgaaggaag aggtgaaggg aattcctgta agagtggcgc 100

 tgcgttgtcg ccctctggtc cccaaagaga ttagcgaggg ctgccagatg 150

 tgcctttcct tcgtgcccgg agagcctcag gtggtggttg gtacagataa 200

 atccttcacc tacgattttg tatttgatcc ctctactgaa caggaagaag 250

 tcttcaatac agcagtagcg ccactcataa aaggtgtatt taaaggatat 300

 aatgcaacgg tcctggccta tgggcagact ggctctggaa aaacctattc 350

 aatgggaggt gcatatactg cagagcaaga gaatgaacca acagttgggg 400

 ttattcctag ggtaatacaa ctgctcttca aagaaattga taaaaagagt 450

 gactttgaat ttactctgaa agtgtcttac ttagagattt acaatgaaga 500

 aattttggat cttctatgtc catctcgtga gaaagctcaa ataaatatac 550

 gagaggatcc taaggaaggc ataaagattg tgggactcac tgagaagact 600

 gttttggttg ccttggatac tgtttcctgt ttggaacagg gcaacaactc 650

 taggactgtg gcctccacgg ctatgaactc ccagtcgtcc cgatctcatg 700

 ccatctttac aatctcctta gagcaaggaa agaaaagtga caagaatagc 750

 agctttcgct ccaagctgca tcttgtagac ctcgctggat cagaaagaca 800

 gaagaaaacc aaggctgaag gggatcgtct aaaagagggt attaatatta 850

 accgaggcct cctatgcttg ggaaatgtaa tcagtgctct tggagatgac 900

 aaaaagggtg gctttgcgcc ctacagagat tccaagttga ctcgactgct 950

 tcaagattct ctaggaggta atagccatac tcttatgata gcctgtgtga 1000

 gtcctgctga ctccaatcta gaggaaacat taaataccct tcgctatgct 1050

 gacagagcaa gaaaaatcaa gaacaaacct attgttaata ttgatcccca 1100

 gacagctgaa cttaatcatc taaagcaaca ggtacaacag ctacaagtct 1150

 tgttgctaca ggcccatgga ggtaccctgc ctggatctat aactgtggaa 1200

 ccatcagaga atctacaatc cctgatggag aagaatcagt ccctggtaga 1250

 ggagaatgaa aaattaagtc gtggtctgag cgaggcagct ggtcagacag 1300

 cccagatgtt ggagaggatc atttggacag agcaagcgaa tgaaaaaatg 1350

 aacgccaagc tagaagagct caggcagcat gcggcctgca aactggatct 1400

 tcaaaagcta gtggagactt tggaagacca ggaattgaaa gaaaatgtag 1450

 agataatttg taacctgcag caattgatta cccagttatc ggatgaaact 1500

 gttgcttgca tggctgcagc cattgatact gcggtggagc aagaagccca 1550

 agtagaaacc agtccagaga cgagcaggtc ttctgacgct tttaccactc 1600

 agcatgctct ccgtcaagcg cagatgtcta aggagctggt tgagttgaat 1650

 aaagcgcttg cactgaaaga ggccctggct aggaagatga ctcagaatga 1700

 cagccaactg cagcctattc agtaccaata ccaggataac ataaaagagc 1750

 cagaattaga agtcatcaat ctgcaaaagg aaaaggaaga attggttctt 1800

 gaacttcaga cagcaaagaa ggatgccaac caagccaagt tgagtgagcg 1850

 ccgccgcaaa cgtctccagg agctggaggg tcaaattgct gatctgaaga 1900

 agaaactgaa tgagcagtcc aaacttctga aactaaagga atccacagag 1950

 cgtactgtct ccaaactgaa ccaggagata cggatgatga aaaaccagcg 2000

 ggtacagtta atgcgtcaaa tgaaagaaga tgctgagaag tttagacagt 2050

 ggaagcagaa aagagacaaa gaagtaatac agttaaaaga acgagaccgt 2100

 aagaggcaat atgagctgct gaaacttgaa agaaacttcc agaaacaatc 2150

 caatgtgctc agacgtaaaa cggaggaggc agcagctgcc aacaagcgtc 2200

 tcaaggatgc tctccagaaa caacgggagg ttgcagataa gcggaaagag 2250

 actcagagcc gtggaatgga aggcactgca gctcgagtga agaattggct 2300

 tggaaacgaa attgaggtta tggtcagtac tgaggaagcc aaacgccatc 2350

 tgaatgacct ccttgaagat agaaagatcc tggctcaaga tgtggctcaa 2400

 ctcaaagaaa aaaaggaatc tggggagaat ccacctccta aactccggag 2450

 gcgtacattc tcccttactg aagtgcgtgg tcaagtttcg gagtcagaag 2500

 attctattac aaagcagatt gaaagcctag agactgaaat ggaattcagg 2550

 agtgctcaga ttgctgacct acagcagaag ctgctggatg cagaaagtga 2600

 agacagacca aaacaacgct gggagaatat tgccaccatt ctggaagcca 2650

 agtgtgccct gaaatatttg attggagagc tggtctcctc caaaatacag 2700

 gtcagcaaac ttgaaagcag cctgaaacag agcaagacca gctgtgctga 2750

 catgcagaag atgctgtttg aggaacgaaa tcattttgcc gagatagaga 2800

 cagagttaca agctgagctg gtcagaatgg agcaacagca ccaagagaag 2850

 gtgctgtacc ttctcagcca gctgcagcaa agccaaatgg cagagaagca 2900

 gttagaggaa tcagtcagtg aaaaggaaca gcagctgctg agcacactga 2950

 agtgtcagga tgaagaactt gagaaaatgc gagaagtgtg tgagcaaaat 3000

 cagcagcttc tccgagagaa tgaaatcatc aagcagaaac tgaccctcct 3050

 ccaggtagcc agcagacaga aacatcttcc taaggatacc cttctatctc 3100

 cagactcttc ttttgaatat gtccagccta agccaaaacc ttctcgtgtt 3150

 aaagaaaagt tcctggagca aagcatggac atcgaggatc taaaatattg 3200

 ttcagagcat tctgtgaatg agcatgagga tggtgatggt gatgatgatg 3250

 agggggatga cgaggaatgg aagccaacaa aattagttaa tgtgtccagg 3300

 aagaacatcc aagggtgttc ctgcaagggc tggtgtggaa acaagcaatg 3350

 tgggtgcagg aagcaaaagt cagactgtgg tgtggactgt tgctgtgacc 3400

 ccacaaagtg tcggaaccgc cagcaaggca aggatagctt gggcactgtt 3450

 gaacggaccc aggattcaga aagctccttc aaactggagg atcctaccga 3500

 ggtgacccca ggattgagct tctttaatcc cgtctgtgcc acccccaata 3550

 gcaagatcct gaaagagatg tgcgatgtgg agcaggtgct gtcaaagaag 3600

 actcccccag ctccctcccc ttttgacctc ccagagttga aacatgtagc 3650

 aacagaatac caagaaaaca aggctccagg gaagaaaaag aaacgggctc 3700

 tggccagcaa caccagcttc ttctctggct gctcccctat cgaagaagag 3750

 gcccactgaa gttggagtca tcatctctac ccccagtctg gcttgggaga 3800

 tgctttcagg ttgcagccag aaggggtttt ttaaatgact tctctggatt 3850

 tcaggtttct tgctgttgaa aaaaggaaca aagcgttact gaaaagaagg 3900

 taacctttgt tggatgtggg ccttagcctc caggtccaga ctactactct 3950

 atgttctcca gaagggtgct aagtcaccta ctgaagagag aaccaactga 4000

 ctttcctatt gactcatcag gaaccagtcc tcagtctggt caagttgttt 4050

 cttatttgtg agcagttcag gctatctcct gatggggatg aggccaaggc 4100

 tttcttatct tttggttgtc tctgcttaat ggaggagcct ggcctaggat 4150

 ggaggcctgg cttagatctt tcattccacc tcaggaatga ggttgtgatc 4200

 tttcctgtcc tgaccctctc tgaattatgt ttcaatagta ctcttgattg 4250

 tctgccatgt tgttgaagca aatgaattat ttttaaatgt taagtaagta 4300

 aataaacctt agcccgtctt tttttttttt tttttttttt tttttttt 4348

<210> 3204
<211> 1232
<212> PRT
<213> Homo sapien

<400> 3204
 Met Lys Glu Glu Val Lys Gly Ile Pro Val Arg Val Ala Leu Arg
   1               5                  10                  15

 Cys Arg Pro Leu Val Pro Lys Glu Ile Ser Glu Gly Cys Gln Met
                  20                  25                  30

 Cys Leu Ser Phe Val Pro Gly Glu Pro Gln Val Val Val Gly Thr
                  35                  40                  45

 Asp Lys Ser Phe Thr Tyr Asp Phe Val Phe Asp Pro Ser Thr Glu
                  50                  55                  60

 Gln Glu Glu Val Phe Asn Thr Ala Val Ala Pro Leu Ile Lys Gly
                  65                  70                  75

 Val Phe Lys Gly Tyr Asn Ala Thr Val Leu Ala Tyr Gly Gln Thr
                  80                  85                  90

 Gly Ser Gly Lys Thr Tyr Ser Met Gly Gly Ala Tyr Thr Ala Glu
                  95                 100                 105

 Gln Glu Asn Glu Pro Thr Val Gly Val Ile Pro Arg Val Ile Gln
                 110                 115                 120

 Leu Leu Phe Lys Glu Ile Asp Lys Lys Ser Asp Phe Glu Phe Thr
                 125                 130                 135

 Leu Lys Val Ser Tyr Leu Glu Ile Tyr Asn Glu Glu Ile Leu Asp
                 140                 145                 150

 Leu Leu Cys Pro Ser Arg Glu Lys Ala Gln Ile Asn Ile Arg Glu
                 155                 160                 165

 Asp Pro Lys Glu Gly Ile Lys Ile Val Gly Leu Thr Glu Lys Thr
                 170                 175                 180

 Val Leu Val Ala Leu Asp Thr Val Ser Cys Leu Glu Gln Gly Asn
                 185                 190                 195

 Asn Ser Arg Thr Val Ala Ser Thr Ala Met Asn Ser Gln Ser Ser
                 200                 205                 210

 Arg Ser His Ala Ile Phe Thr Ile Ser Leu Glu Gln Gly Lys Lys
                 215                 220                 225

 Ser Asp Lys Asn Ser Ser Phe Arg Ser Lys Leu His Leu Val Asp
                 230                 235                 240

 Leu Ala Gly Ser Glu Arg Gln Lys Lys Thr Lys Ala Glu Gly Asp
                 245                 250                 255

 Arg Leu Lys Glu Gly Ile Asn Ile Asn Arg Gly Leu Leu Cys Leu
                 260                 265                 270

 Gly Asn Val Ile Ser Ala Leu Gly Asp Asp Lys Lys Gly Gly Phe
                 275                 280                 285

 Ala Pro Tyr Arg Asp Ser Lys Leu Thr Arg Leu Leu Gln Asp Ser
                 290                 295                 300

 Leu Gly Gly Asn Ser His Thr Leu Met Ile Ala Cys Val Ser Pro
                 305                 310                 315

 Ala Asp Ser Asn Leu Glu Glu Thr Leu Asn Thr Leu Arg Tyr Ala
                 320                 325                 330

 Asp Arg Ala Arg Lys Ile Lys Asn Lys Pro Ile Val Asn Ile Asp
                 335                 340                 345

 Pro Gln Thr Ala Glu Leu Asn His Leu Lys Gln Gln Val Gln Gln
                 350                 355                 360

 Leu Gln Val Leu Leu Leu Gln Ala His Gly Gly Thr Leu Pro Gly
                 365                 370                 375

 Ser Ile Thr Val Glu Pro Ser Glu Asn Leu Gln Ser Leu Met Glu
                 380                 385                 390

 Lys Asn Gln Ser Leu Val Glu Glu Asn Glu Lys Leu Ser Arg Gly
                 395                 400                 405

 Leu Ser Glu Ala Ala Gly Gln Thr Ala Gln Met Leu Glu Arg Ile
                 410                 415                 420

 Ile Trp Thr Glu Gln Ala Asn Glu Lys Met Asn Ala Lys Leu Glu
                 425                 430                 435

 Glu Leu Arg Gln His Ala Ala Cys Lys Leu Asp Leu Gln Lys Leu
                 440                 445                 450

 Val Glu Thr Leu Glu Asp Gln Glu Leu Lys Glu Asn Val Glu Ile
                 455                 460                 465

 Ile Cys Asn Leu Gln Gln Leu Ile Thr Gln Leu Ser Asp Glu Thr
                 470                 475                 480

 Val Ala Cys Met Ala Ala Ala Ile Asp Thr Ala Val Glu Gln Glu
                 485                 490                 495

 Ala Gln Val Glu Thr Ser Pro Glu Thr Ser Arg Ser Ser Asp Ala
                 500                 505                 510

 Phe Thr Thr Gln His Ala Leu Arg Gln Ala Gln Met Ser Lys Glu
                 515                 520                 525

 Leu Val Glu Leu Asn Lys Ala Leu Ala Leu Lys Glu Ala Leu Ala
                 530                 535                 540

 Arg Lys Met Thr Gln Asn Asp Ser Gln Leu Gln Pro Ile Gln Tyr
                 545                 550                 555

 Gln Tyr Gln Asp Asn Ile Lys Glu Pro Glu Leu Glu Val Ile Asn
                 560                 565                 570

 Leu Gln Lys Glu Lys Glu Glu Leu Val Leu Glu Leu Gln Thr Ala
                 575                 580                 585

 Lys Lys Asp Ala Asn Gln Ala Lys Leu Ser Glu Arg Arg Arg Lys
                 590                 595                 600

 Arg Leu Gln Glu Leu Glu Gly Gln Ile Ala Asp Leu Lys Lys Lys
                 605                 610                 615

 Leu Asn Glu Gln Ser Lys Leu Leu Lys Leu Lys Glu Ser Thr Glu
                 620                 625                 630

 Arg Thr Val Ser Lys Leu Asn Gln Glu Ile Arg Met Met Lys Asn
                 635                 640                 645

 Gln Arg Val Gln Leu Met Arg Gln Met Lys Glu Asp Ala Glu Lys
                 650                 655                 660

 Phe Arg Gln Trp Lys Gln Lys Arg Asp Lys Glu Val Ile Gln Leu
                 665                 670                 675

 Lys Glu Arg Asp Arg Lys Arg Gln Tyr Glu Leu Leu Lys Leu Glu
                 680                 685                 690

 Arg Asn Phe Gln Lys Gln Ser Asn Val Leu Arg Arg Lys Thr Glu
                 695                 700                 705

 Glu Ala Ala Ala Ala Asn Lys Arg Leu Lys Asp Ala Leu Gln Lys
                 710                 715                 720

 Gln Arg Glu Val Ala Asp Lys Arg Lys Glu Thr Gln Ser Arg Gly
                 725                 730                 735

 Met Glu Gly Thr Ala Ala Arg Val Lys Asn Trp Leu Gly Asn Glu
                 740                 745                 750

 Ile Glu Val Met Val Ser Thr Glu Glu Ala Lys Arg His Leu Asn
                 755                 760                 765

 Asp Leu Leu Glu Asp Arg Lys Ile Leu Ala Gln Asp Val Ala Gln
                 770                 775                 780

 Leu Lys Glu Lys Lys Glu Ser Gly Glu Asn Pro Pro Pro Lys Leu
                 785                 790                 795

 Arg Arg Arg Thr Phe Ser Leu Thr Glu Val Arg Gly Gln Val Ser
                 800                 805                 810

 Glu Ser Glu Asp Ser Ile Thr Lys Gln Ile Glu Ser Leu Glu Thr
                 815                 820                 825

 Glu Met Glu Phe Arg Ser Ala Gln Ile Ala Asp Leu Gln Gln Lys
                 830                 835                 840

 Leu Leu Asp Ala Glu Ser Glu Asp Arg Pro Lys Gln Arg Trp Glu
                 845                 850                 855

 Asn Ile Ala Thr Ile Leu Glu Ala Lys Cys Ala Leu Lys Tyr Leu
                 860                 865                 870

 Ile Gly Glu Leu Val Ser Ser Lys Ile Gln Val Ser Lys Leu Glu
                 875                 880                 885

 Ser Ser Leu Lys Gln Ser Lys Thr Ser Cys Ala Asp Met Gln Lys
                 890                 895                 900

 Met Leu Phe Glu Glu Arg Asn His Phe Ala Glu Ile Glu Thr Glu
                 905                 910                 915

 Leu Gln Ala Glu Leu Val Arg Met Glu Gln Gln His Gln Glu Lys
                 920                 925                 930

 Val Leu Tyr Leu Leu Ser Gln Leu Gln Gln Ser Gln Met Ala Glu
                 935                 940                 945

 Lys Gln Leu Glu Glu Ser Val Ser Glu Lys Glu Gln Gln Leu Leu
                 950                 955                 960

 Ser Thr Leu Lys Cys Gln Asp Glu Glu Leu Glu Lys Met Arg Glu
                 965                 970                 975

 Val Cys Glu Gln Asn Gln Gln Leu Leu Arg Glu Asn Glu Ile Ile
                 980                 985                 990

 Lys Gln Lys Leu Thr Leu Leu Gln Val Ala Ser Arg Gln Lys His
                 995                1000                1005

 Leu Pro Lys Asp Thr Leu Leu Ser Pro Asp Ser Ser Phe Glu Tyr
                1010                1015                1020

 Val Gln Pro Lys Pro Lys Pro Ser Arg Val Lys Glu Lys Phe Leu
                1025                1030                1035

 Glu Gln Ser Met Asp Ile Glu Asp Leu Lys Tyr Cys Ser Glu His
                1040                1045                1050

 Ser Val Asn Glu His Glu Asp Gly Asp Gly Asp Asp Asp Glu Gly
                1055                1060                1065

 Asp Asp Glu Glu Trp Lys Pro Thr Lys Leu Val Asn Val Ser Arg
                1070                1075                1080

 Lys Asn Ile Gln Gly Cys Ser Cys Lys Gly Trp Cys Gly Asn Lys
                1085                1090                1095

 Gln Cys Gly Cys Arg Lys Gln Lys Ser Asp Cys Gly Val Asp Cys
                1100                1105                1110

 Cys Cys Asp Pro Thr Lys Cys Arg Asn Arg Gln Gln Gly Lys Asp
                1115                1120                1125

 Ser Leu Gly Thr Val Glu Arg Thr Gln Asp Ser Glu Ser Ser Phe
                1130                1135                1140

 Lys Leu Glu Asp Pro Thr Glu Val Thr Pro Gly Leu Ser Phe Phe
                1145                1150                1155

 Asn Pro Val Cys Ala Thr Pro Asn Ser Lys Ile Leu Lys Glu Met
                1160                1165                1170

 Cys Asp Val Glu Gln Val Leu Ser Lys Lys Thr Pro Pro Ala Pro
                1175                1180                1185

 Ser Pro Phe Asp Leu Pro Glu Leu Lys His Val Ala Thr Glu Tyr
                1190                1195                1200

 Gln Glu Asn Lys Ala Pro Gly Lys Lys Lys Lys Arg Ala Leu Ala
                1205                1210                1215

 Ser Asn Thr Ser Phe Phe Ser Gly Cys Ser Pro Ile Glu Glu Glu
                1220                1225                1230

 Ala His


<210> 3205
<211> 1763
<212> DNA
<213> Homo sapien

<400> 3205
 atcaagcagg ggcagggctg gcgctgcggc gggagatgct gtcgggccgc 50

 ggcggcgctt ggcagccagg agctctgcat tgaaggcact ggggtaaagt 100

 gaatgccgaa gacagaagat ttggatgata caccactgac tttctttgtt 150

 tggaatacac gttatgaacc ctttctggag catgtctaca agctctgtac 200

 gcaaacgatc tgaaggtgaa gagaagacat taacagggga cgtgaaaacc 250

 agtcctccac gaactgcacc aaagaaacag ctgccttcta ttcccaaaaa 300

 tgctttgccc ataactaagc ctacatctcc tgccccagca gcacagtcaa 350

 caaatggcac gcatgcgtcc tatggaccct tctacctgga atactctctt 400

 cttgcagaat ttaccttggt tgtgaagcag aagctaccag gcgtctatgt 450

 gcagccatct tatcgctctg cattaatgtg gtttggagta atattcatac 500

 ggcatggact ttaccaagat ggcgtattta agtttacagt ttacatccct 550

 gataactatc cagatggtga ctgtccacgc ttggtgttcg atattcctgt 600

 ctttcacccg ctagttgatc ccacctcagg tgagctggat gtgaagagag 650

 catttgcaaa atggaggcgg aaccataatc atatttggca ggtattaatg 700

 tatgcaagga gagttttcta caagattgat acagcaagcc ccctgaaccc 750

 agaggctgca gtactgtatg aaaaagatat tcagcttttt aaaagtaaag 800

 ttgttgacag tgttaaggtg tgcactgctc gtttgtttga ccaacctaaa 850

 atagaagacc cctatgcaat tagcttttct ccatggaatc cttctgtaca 900

 tgatgaagcc agagaaaaga tgctgactca gaaaaagcct gaagaacagc 950

 acaataaaag tgttcatgtt gctggcctgt catgggtaaa gcctggctca 1000

 gtacagcctt tcagtaaaga agagaaaaca gtggcgactt aagagatggt 1050

 gaatctggtg caccatgcac tttcctgcta gactctggcc tagttcaagc 1100

 tgaccaatgg cagaggactg cctgaagagt aaaactgtgt gaacaatgac 1150

 tgactgccag tgttttccat gtatgcatag gttctaacag cagggtttgg 1200

 aaacctgtct ctaagtaatg cattacttct gtcagaagtg tcttagggtg 1250

 gttatctagt tcagtactcc aaattattgg ggaccttgag gcttaagtaa 1300

 gtatttttct gaatataatg ctaaaggtaa gttgcattca tttaaactaa 1350

 tagagcagac agaattcagc actacttaat agtttataaa tcagtggttt 1400

 cagttgtata tatgttagga aatggagagg tatagagaga gcaggttcca 1450

 tagctcagca cttttaagtg gaagatcatt tgaatctcag tcttcagcct 1500

 gcactgattt gtagcctgca ctgtcttact gatttacaaa ctgaaatcac 1550

 tgagaaatgt ctttagttca gtgagaagaa accagaacac ttgttcctag 1600

 tgttgtgttg ttttttttaa gcaaattact tactgtattt ttatggcagg 1650

 agggagaaaa agtgttacaa cggcttctaa tgaagtccgg tatttaaatg 1700

 ataaatgact aatgtgttta gtagagacaa aataaaccaa taaatgattg 1750

 ttctttgcca ttt 1763

<210> 3206
<211> 292
<212> PRT
<213> Homo sapien

<400> 3206
 Met Asn Pro Phe Trp Ser Met Ser Thr Ser Ser Val Arg Lys Arg
   1               5                  10                  15

 Ser Glu Gly Glu Glu Lys Thr Leu Thr Gly Asp Val Lys Thr Ser
                  20                  25                  30

 Pro Pro Arg Thr Ala Pro Lys Lys Gln Leu Pro Ser Ile Pro Lys
                  35                  40                  45

 Asn Ala Leu Pro Ile Thr Lys Pro Thr Ser Pro Ala Pro Ala Ala
                  50                  55                  60

 Gln Ser Thr Asn Gly Thr His Ala Ser Tyr Gly Pro Phe Tyr Leu
                  65                  70                  75

 Glu Tyr Ser Leu Leu Ala Glu Phe Thr Leu Val Val Lys Gln Lys
                  80                  85                  90

 Leu Pro Gly Val Tyr Val Gln Pro Ser Tyr Arg Ser Ala Leu Met
                  95                 100                 105

 Trp Phe Gly Val Ile Phe Ile Arg His Gly Leu Tyr Gln Asp Gly
                 110                 115                 120

 Val Phe Lys Phe Thr Val Tyr Ile Pro Asp Asn Tyr Pro Asp Gly
                 125                 130                 135

 Asp Cys Pro Arg Leu Val Phe Asp Ile Pro Val Phe His Pro Leu
                 140                 145                 150

 Val Asp Pro Thr Ser Gly Glu Leu Asp Val Lys Arg Ala Phe Ala
                 155                 160                 165

 Lys Trp Arg Arg Asn His Asn His Ile Trp Gln Val Leu Met Tyr
                 170                 175                 180

 Ala Arg Arg Val Phe Tyr Lys Ile Asp Thr Ala Ser Pro Leu Asn
                 185                 190                 195

 Pro Glu Ala Ala Val Leu Tyr Glu Lys Asp Ile Gln Leu Phe Lys
                 200                 205                 210

 Ser Lys Val Val Asp Ser Val Lys Val Cys Thr Ala Arg Leu Phe
                 215                 220                 225

 Asp Gln Pro Lys Ile Glu Asp Pro Tyr Ala Ile Ser Phe Ser Pro
                 230                 235                 240

 Trp Asn Pro Ser Val His Asp Glu Ala Arg Glu Lys Met Leu Thr
                 245                 250                 255

 Gln Lys Lys Pro Glu Glu Gln His Asn Lys Ser Val His Val Ala
                 260                 265                 270

 Gly Leu Ser Trp Val Lys Pro Gly Ser Val Gln Pro Phe Ser Lys
                 275                 280                 285

 Glu Glu Lys Thr Val Ala Thr
                 290

<210> 3207
<211> 3697
<212> DNA
<213> Homo sapien

<400> 3207
 cccaagactg tccccgctgg aggcggtaga gggatccaga agtaatgaga 50

 tgctaatgag tcgcgaataa agcccgggcg gcgccccgcg cccctcgcgg 100

 aagcccacac tccgcgcgac tccaggcgca cgccccgggc cgccccgcat 150

 cccagcatcc ccgcccgatc tcggcgtttc cgcccccgcc cccgcccccg 200

 ccctcccacc cgctcagacc tggttgccag cccaacagga agcggcccct 250

 cccggcttcg gagccgccgc cactcgtctc tgcccagctg ctgccctccc 300

 caggaggcct ccatggcttc acctacctcc accaacccag cgcatgccca 350

 ctttgagagc ttcctgcagg cccagctgtg ccaggacgtg ctgagcagct 400

 tccaggagct gtgtggggcc ctggggctgg aacccggtgg ggggctgccc 450

 cagtaccaca agatcaagga ccagctcaac tactggagcg ccaagtcact 500

 gtggaccaag ctggacaagc gagcaggcca gcctgtctac cagcagggcc 550

 gggcctgcac cagcaccaag tgcctggtgg tgggtgctgg accttgcggg 600

 ctgcgggtcg ctgtggagct ggcgctgctg ggggcccgag tggtgctggt 650

 ggaaaagcgc accaagttct ctcgccacaa cgtgctccac ctctggccct 700

 tcaccatcca cgacctgcgg gcactcggtg ctaagaagtt ctacgggcgc 750

 ttctgcaccg gcaccctgga ccacatcagc atcaggcagc tccagctgct 800

 tctgctgaag gtagcattgc tgctgggggt ggaaattcac tggggtgtca 850

 ctttcactgg cctccagccc cctcctagga aggggagtgg ctggcgtgcc 900

 cagctccaac ccaacccccc tgcccagctg gccaactatg aatttgacgt 950

 ccttatctcg gctgcaggag gtaaattcgt ccctgaaggc ttcaaagttc 1000

 gagaaatgcg aggcaaactg gccattggca tcacagccaa ctttgtgaat 1050

 ggacgcaccg tggaggagac acaggtgccg gagatcagtg gtgtagccag 1100

 gatctacaac cagagcttct tccagagcct tctcaaagcc acaggcattg 1150

 atctggagaa cattgtgtac tacaaggacg acacccacta ctttgtgatg 1200

 acagccaaga agcagtgcct gctgcggctg ggggtgctgc gccaggactg 1250

 gccagacacc aatcggctgc tgggcagtgc caatgtggtg cccgaggctc 1300

 tgcagcgctt tacccgggca gctgctgact ttgccaccca tggcaagctc 1350

 gggaaactag agtttgccca ggatgcccat gggcagcctg atgtctctgc 1400

 ctttgacttc acgagcatga tgcgggcaga gagttctgct cgtgtgcaag 1450

 agaagcatgg cgcccgcctg ctgctgggac tggtggggga ctgcctggtg 1500

 gagcccttct ggcccctggg cactggagtg gcacggggct tcctggcagc 1550

 ctttgatgca gcctggatgg tgaagcggtg ggcagagggc gctgagtccc 1600

 tagaggtgtt ggctgagcgt gagagcctgt accagcttct gtcacagaca 1650

 tccccagaaa acatgcatcg caatgtggcc cagtatgggc tggacccagc 1700

 cacccgctac cccaacctga acctccgggc agtgaccccc aatcaggtac 1750

 gagacctgta tgatgtgcta gccaaggagc ctgtgcagag gaacaacgac 1800

 aagacagata cagggatgcc agccaccggg tcggcaggca cccaggagga 1850

 gctgctacgc tggtgccagg agcagacagc tgggtacccg ggagtccacg 1900

 tctccgattt gtcttcctcc tgggctgatg ggctagctct gtgtgccctg 1950

 gtgtaccggc tgcagcctgg cctgctggaa ccctcagagc tgcaggggct 2000

 gggagctctg gaagcaactg cttgggcact aaaggtggca gagaatgagc 2050

 tgggcatcac accggtggtg tctgcacagg ccgtggtagc agggagtgac 2100

 ccactgggcc tcattgccta cctcagccac ttccacagtg ccttcaagag 2150

 catggcccac agcccaggcc ctgtcagcca ggcctcccca gggacctcca 2200

 gtgctgtatt attccttagt aaacttcaga ggaccctgca gcgatcccgg 2250

 gccaaggaaa atgcagagga tgctggtggc aagaagctgc gcttggagat 2300

 ggaggccgag accccaagta ctgaggtgcc acctgaccca gagcctggtg 2350

 tacccctgac acccccatcc caacaccagg aggccggtgc tggggacctg 2400

 tgtgcacttt gtggggaaca cctctatgtc ctggaacgcc tctgtgtcaa 2450

 cggccatttc ttccaccgga gctgcttccg ctgccatacc tgtgaggcca 2500

 cactgtggcc aggtggctat gagcagcacc caggagatgg acatttctac 2550

 tgcctccagc acctgcccca gacagaccac aaaaaggaag gcagcgatag 2600

 aggccctgag agtccggagc tccccacacc aagtgagaat agcatgccac 2650

 caggcctctc aactcccaca gcctcgcagg agggggccgg tcctgttcca 2700

 gatcccagcc agcccacccg tcggcagatc cgcctctcca gcccggagcg 2750

 ccagcggttg tcctccctta accttacccc tgacccggaa atggagcctc 2800

 cacccaagcc tccccgcagc tgctccgcct tggcccgcca cgccctggag 2850

 agcagctttg tgggctgggg cctgccagtc cagagccctc aagctcttgt 2900

 ggccatggag aaggaggaaa aagagagtcc cttctccagt gaagaggaag 2950

 aagaagatgt gcctttggac tcagatgtgg aacaggccct gcagaccttt 3000

 gccaagacct caggcaccat gaataactac ccaacatggc gtcggactct 3050

 gctgcgccgt gcgaaggagg aggagatgaa gaggttctgc aaggcccaga 3100

 ccatccaacg gcgactaaat gagattgagg ctgccttgag ggagctagag 3150

 gccgagggcg tgaagctgga gctggccttg aggcgccaga gcagttcccc 3200

 agaacagcaa aagaaactat gggtaggaca gctgctacag ctcgttgaca 3250

 agaaaaacag cttggtggct gaggaggccg agctcatgat cacggtgcag 3300

 gaattgaatc tggaggagaa acagtggcag ctggaccagg agctacgagg 3350

 ctacatgaac cgggaagaaa acctaaagac agctgctgat cggcaggctg 3400

 aggaccaggt cctgaggaag ctggtggatt tggtcaacca gagagatgcc 3450

 ctcatccgct tccaggagga gcgcaggctc agcgagctgg ccttggggac 3500

 aggggcccag ggctagacga gggtgggccg tctgctttcg ttcccacaaa 3550

 gaaagcacct caccccagca cagtgccacc cctgttcatc tgggctgcct 3600

 ggcagagagc cttgctgttt acaattaaaa tgtttctgcc ccaaaaaaaa 3650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 3697

<210> 3208
<211> 1067
<212> PRT
<213> Homo sapien

<400> 3208
 Met Ala Ser Pro Thr Ser Thr Asn Pro Ala His Ala His Phe Glu
   1               5                  10                  15

 Ser Phe Leu Gln Ala Gln Leu Cys Gln Asp Val Leu Ser Ser Phe
                  20                  25                  30

 Gln Glu Leu Cys Gly Ala Leu Gly Leu Glu Pro Gly Gly Gly Leu
                  35                  40                  45

 Pro Gln Tyr His Lys Ile Lys Asp Gln Leu Asn Tyr Trp Ser Ala
                  50                  55                  60

 Lys Ser Leu Trp Thr Lys Leu Asp Lys Arg Ala Gly Gln Pro Val
                  65                  70                  75

 Tyr Gln Gln Gly Arg Ala Cys Thr Ser Thr Lys Cys Leu Val Val
                  80                  85                  90

 Gly Ala Gly Pro Cys Gly Leu Arg Val Ala Val Glu Leu Ala Leu
                  95                 100                 105

 Leu Gly Ala Arg Val Val Leu Val Glu Lys Arg Thr Lys Phe Ser
                 110                 115                 120

 Arg His Asn Val Leu His Leu Trp Pro Phe Thr Ile His Asp Leu
                 125                 130                 135

 Arg Ala Leu Gly Ala Lys Lys Phe Tyr Gly Arg Phe Cys Thr Gly
                 140                 145                 150

 Thr Leu Asp His Ile Ser Ile Arg Gln Leu Gln Leu Leu Leu Leu
                 155                 160                 165

 Lys Val Ala Leu Leu Leu Gly Val Glu Ile His Trp Gly Val Thr
                 170                 175                 180

 Phe Thr Gly Leu Gln Pro Pro Pro Arg Lys Gly Ser Gly Trp Arg
                 185                 190                 195

 Ala Gln Leu Gln Pro Asn Pro Pro Ala Gln Leu Ala Asn Tyr Glu
                 200                 205                 210

 Phe Asp Val Leu Ile Ser Ala Ala Gly Gly Lys Phe Val Pro Glu
                 215                 220                 225

 Gly Phe Lys Val Arg Glu Met Arg Gly Lys Leu Ala Ile Gly Ile
                 230                 235                 240

 Thr Ala Asn Phe Val Asn Gly Arg Thr Val Glu Glu Thr Gln Val
                 245                 250                 255

 Pro Glu Ile Ser Gly Val Ala Arg Ile Tyr Asn Gln Ser Phe Phe
                 260                 265                 270

 Gln Ser Leu Leu Lys Ala Thr Gly Ile Asp Leu Glu Asn Ile Val
                 275                 280                 285

 Tyr Tyr Lys Asp Asp Thr His Tyr Phe Val Met Thr Ala Lys Lys
                 290                 295                 300

 Gln Cys Leu Leu Arg Leu Gly Val Leu Arg Gln Asp Trp Pro Asp
                 305                 310                 315

 Thr Asn Arg Leu Leu Gly Ser Ala Asn Val Val Pro Glu Ala Leu
                 320                 325                 330

 Gln Arg Phe Thr Arg Ala Ala Ala Asp Phe Ala Thr His Gly Lys
                 335                 340                 345

 Leu Gly Lys Leu Glu Phe Ala Gln Asp Ala His Gly Gln Pro Asp
                 350                 355                 360

 Val Ser Ala Phe Asp Phe Thr Ser Met Met Arg Ala Glu Ser Ser
                 365                 370                 375

 Ala Arg Val Gln Glu Lys His Gly Ala Arg Leu Leu Leu Gly Leu
                 380                 385                 390

 Val Gly Asp Cys Leu Val Glu Pro Phe Trp Pro Leu Gly Thr Gly
                 395                 400                 405

 Val Ala Arg Gly Phe Leu Ala Ala Phe Asp Ala Ala Trp Met Val
                 410                 415                 420

 Lys Arg Trp Ala Glu Gly Ala Glu Ser Leu Glu Val Leu Ala Glu
                 425                 430                 435

 Arg Glu Ser Leu Tyr Gln Leu Leu Ser Gln Thr Ser Pro Glu Asn
                 440                 445                 450

 Met His Arg Asn Val Ala Gln Tyr Gly Leu Asp Pro Ala Thr Arg
                 455                 460                 465

 Tyr Pro Asn Leu Asn Leu Arg Ala Val Thr Pro Asn Gln Val Arg
                 470                 475                 480

 Asp Leu Tyr Asp Val Leu Ala Lys Glu Pro Val Gln Arg Asn Asn
                 485                 490                 495

 Asp Lys Thr Asp Thr Gly Met Pro Ala Thr Gly Ser Ala Gly Thr
                 500                 505                 510

 Gln Glu Glu Leu Leu Arg Trp Cys Gln Glu Gln Thr Ala Gly Tyr
                 515                 520                 525

 Pro Gly Val His Val Ser Asp Leu Ser Ser Ser Trp Ala Asp Gly
                 530                 535                 540

 Leu Ala Leu Cys Ala Leu Val Tyr Arg Leu Gln Pro Gly Leu Leu
                 545                 550                 555

 Glu Pro Ser Glu Leu Gln Gly Leu Gly Ala Leu Glu Ala Thr Ala
                 560                 565                 570

 Trp Ala Leu Lys Val Ala Glu Asn Glu Leu Gly Ile Thr Pro Val
                 575                 580                 585

 Val Ser Ala Gln Ala Val Val Ala Gly Ser Asp Pro Leu Gly Leu
                 590                 595                 600

 Ile Ala Tyr Leu Ser His Phe His Ser Ala Phe Lys Ser Met Ala
                 605                 610                 615

 His Ser Pro Gly Pro Val Ser Gln Ala Ser Pro Gly Thr Ser Ser
                 620                 625                 630

 Ala Val Leu Phe Leu Ser Lys Leu Gln Arg Thr Leu Gln Arg Ser
                 635                 640                 645

 Arg Ala Lys Glu Asn Ala Glu Asp Ala Gly Gly Lys Lys Leu Arg
                 650                 655                 660

 Leu Glu Met Glu Ala Glu Thr Pro Ser Thr Glu Val Pro Pro Asp
                 665                 670                 675

 Pro Glu Pro Gly Val Pro Leu Thr Pro Pro Ser Gln His Gln Glu
                 680                 685                 690

 Ala Gly Ala Gly Asp Leu Cys Ala Leu Cys Gly Glu His Leu Tyr
                 695                 700                 705

 Val Leu Glu Arg Leu Cys Val Asn Gly His Phe Phe His Arg Ser
                 710                 715                 720

 Cys Phe Arg Cys His Thr Cys Glu Ala Thr Leu Trp Pro Gly Gly
                 725                 730                 735

 Tyr Glu Gln His Pro Gly Asp Gly His Phe Tyr Cys Leu Gln His
                 740                 745                 750

 Leu Pro Gln Thr Asp His Lys Lys Glu Gly Ser Asp Arg Gly Pro
                 755                 760                 765

 Glu Ser Pro Glu Leu Pro Thr Pro Ser Glu Asn Ser Met Pro Pro
                 770                 775                 780

 Gly Leu Ser Thr Pro Thr Ala Ser Gln Glu Gly Ala Gly Pro Val
                 785                 790                 795

 Pro Asp Pro Ser Gln Pro Thr Arg Arg Gln Ile Arg Leu Ser Ser
                 800                 805                 810

 Pro Glu Arg Gln Arg Leu Ser Ser Leu Asn Leu Thr Pro Asp Pro
                 815                 820                 825

 Glu Met Glu Pro Pro Pro Lys Pro Pro Arg Ser Cys Ser Ala Leu
                 830                 835                 840

 Ala Arg His Ala Leu Glu Ser Ser Phe Val Gly Trp Gly Leu Pro
                 845                 850                 855

 Val Gln Ser Pro Gln Ala Leu Val Ala Met Glu Lys Glu Glu Lys
                 860                 865                 870

 Glu Ser Pro Phe Ser Ser Glu Glu Glu Glu Glu Asp Val Pro Leu
                 875                 880                 885

 Asp Ser Asp Val Glu Gln Ala Leu Gln Thr Phe Ala Lys Thr Ser
                 890                 895                 900

 Gly Thr Met Asn Asn Tyr Pro Thr Trp Arg Arg Thr Leu Leu Arg
                 905                 910                 915

 Arg Ala Lys Glu Glu Glu Met Lys Arg Phe Cys Lys Ala Gln Thr
                 920                 925                 930

 Ile Gln Arg Arg Leu Asn Glu Ile Glu Ala Ala Leu Arg Glu Leu
                 935                 940                 945

 Glu Ala Glu Gly Val Lys Leu Glu Leu Ala Leu Arg Arg Gln Ser
                 950                 955                 960

 Ser Ser Pro Glu Gln Gln Lys Lys Leu Trp Val Gly Gln Leu Leu
                 965                 970                 975

 Gln Leu Val Asp Lys Lys Asn Ser Leu Val Ala Glu Glu Ala Glu
                 980                 985                 990

 Leu Met Ile Thr Val Gln Glu Leu Asn Leu Glu Glu Lys Gln Trp
                 995                1000                1005

 Gln Leu Asp Gln Glu Leu Arg Gly Tyr Met Asn Arg Glu Glu Asn
                1010                1015                1020

 Leu Lys Thr Ala Ala Asp Arg Gln Ala Glu Asp Gln Val Leu Arg
                1025                1030                1035

 Lys Leu Val Asp Leu Val Asn Gln Arg Asp Ala Leu Ile Arg Phe
                1040                1045                1050

 Gln Glu Glu Arg Arg Leu Ser Glu Leu Ala Leu Gly Thr Gly Ala
                1055                1060                1065

 Gln Gly


<210> 3209
<211> 1561
<212> DNA
<213> Homo sapien

<400> 3209
 ggctgaccca cctacccgcg atcctgccca tggctgacgg gctctttcgg 50

 cgcagaccct ggggtctcga gcagattcgc ccggaccccg agtccgaagg 100

 cctgtttgac aagcctcccc cggaagaccc tcccgctgcc cgcgggccca 150

 ggtcggcgtc ggccgcgggc aagaaggctg gtcggcgcgc gggcgggagg 200

 gcgcaggggg gccgcgccgg gcagcccccg aaggccgcat cgcacccccc 250

 gcccaagaag gaggcgcctc cactggacga gggctgctat ctcgaccatt 300

 ttccgcacct ctccatcttc atctacgcag ccatcgcctt ctccatcacc 350

 tcctgcatct ttacctatat ccatttacag cttgcctgag tggccagcgc 400

 gggacggggt gggcgcagga ccgagcgggg agggaaaggg aaaacggggc 450

 tcggcatttt gtgttttaga acagcgctgc acccccttca tgtagctttc 500

 gatgcttgtt tctttccgtc tttgttgtca ctatctttgt ctatcagtac 550

 gaaagtacaa agtagctgcc ggcaatgaaa taggggtgct gtttgcacct 600

 gcaggttagg ggtggaggcg tttagaattt tggggtgtga ttgagccccg 650

 tttataatta gaatgcccct ggacccctac cactctgtga cgtgggggca 700

 cgcgcaggga tcccatcatt ttgtgtttgg ggagctcaga gtgcgcccaa 750

 tcttggaatc tttaagggat gagccagacc cagacccgcg gccttctaga 800

 gagggtccgg cagggagggt cggcgccctg gcccgggatg ggccggagcc 850

 ctgtgatgct gcatcgcccc caggaggagc cagctgtgcc ccagagttgg 900

 cgcggccgag agaggacaag agcgcgcagc aggcgaagct ggagggcggg 950

 actcgacttt gttgtcgctg cccggaggag tcgagactgg tacccggagg 1000

 agctgtctca ccaggagacc acgtcctgga agtgtccggg actcgcggga 1050

 cctgtggctg cagaccccgc cggcacgcag gcccagagct ggcgcactcc 1100

 tgaggatgag actctggggg ccctagccgg ggtccacggg agggctgtcc 1150

 ttggggactc taggatggct tcgttctggc ccggctcact tctggagctg 1200

 tgagacccaa gacaaaaggg gctgagggat ttctcattga caagagttcg 1250

 tgcgggaaaa ccacctgacc cctagggatt tgtcatctta agactcaaaa 1300

 ggcttaatac caggaaccac cttggcaaga tatttaccca ccggccatct 1350

 ctgtttactc atgaatgtta aatgttaaaa cgcagcgctc taaccctgca 1400

 tattatttac ttgcaaatgt ctgtaatctg taattgtgat gcctctgatg 1450

 gaataaatta tctttttcag tctcctctaa aaaaaaaaaa aaaaaaaaaa 1500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1550

 aaaaaaaaaa a 1561

<210> 3210
<211> 146
<212> PRT
<213> Homo sapien

<400> 3210
 Met Pro Leu Asp Pro Tyr His Ser Val Thr Trp Gly His Ala Gln
   1               5                  10                  15

 Gly Ser His His Phe Val Phe Gly Glu Leu Arg Val Arg Pro Ile
                  20                  25                  30

 Leu Glu Ser Leu Arg Asp Glu Pro Asp Pro Asp Pro Arg Pro Ser
                  35                  40                  45

 Arg Glu Gly Pro Ala Gly Arg Val Gly Ala Leu Ala Arg Asp Gly
                  50                  55                  60

 Pro Glu Pro Cys Asp Ala Ala Ser Pro Pro Gly Gly Ala Ser Cys
                  65                  70                  75

 Ala Pro Glu Leu Ala Arg Pro Arg Glu Asp Lys Ser Ala Gln Gln
                  80                  85                  90

 Ala Lys Leu Glu Gly Gly Thr Arg Leu Cys Cys Arg Cys Pro Glu
                  95                 100                 105

 Glu Ser Arg Leu Val Pro Gly Gly Ala Val Ser Pro Gly Asp His
                 110                 115                 120

 Val Leu Glu Val Ser Gly Thr Arg Gly Thr Cys Gly Cys Arg Pro
                 125                 130                 135

 Arg Arg His Ala Gly Pro Glu Leu Ala His Ser
                 140                 145

<210> 3211
<211> 722
<212> DNA
<213> Homo sapien

<400> 3211
 cagggtcagc catgtcatct gagcctcccc caccaccaca gccccccacc 50

 catcaagctt cagtcgggct gctggacacc cctcggagcc gtgagcgctc 100

 accatcccct ctgcggggca acgtggtccc aagcccactg cccactcgcc 150

 ggacgaggac cttctcggcg acggtgcggg cttcacaggt ccccgtctac 200

 aaaggagtct gcaaatgctt ctgccggtcc aagggccatg gcttcattac 250

 cccagctgat ggcggccccg acatcttcct gcacatctct gatgtggaag 300

 gggagtatgt cccagtggaa ggcgacgagg tcacctataa aatgtgctcc 350

 atcccaccca agaatgagaa gctgcaggcc gtggaggtcg tcatcactca 400

 cctggcacca ggcaccaagc atgagacctg gtctggacat gtcatcagct 450

 cctaggagat ggtggaagca ccccttgtcc tgtgcttgag gagactttgc 500

 ggggaggagg cagcagacac tggagatgac attcttccac acgagacggg 550

 gcttcagccg gggatggtcc ctctcaagta tctcctggag gaaggggtat 600

 ggggggcagg tgtggggtgt ggggtgttcc cggccatcag cacagcctat 650

 gaccattgca acaacctctc accatctgaa gagcattaaa agcatttaaa 700

 aaggaaaaaa aaaaaaaaaa aa 722

<210> 3212
<211> 147
<212> PRT
<213> Homo sapien

<400> 3212
 Met Ser Ser Glu Pro Pro Pro Pro Pro Gln Pro Pro Thr His Gln
   1               5                  10                  15

 Ala Ser Val Gly Leu Leu Asp Thr Pro Arg Ser Arg Glu Arg Ser
                  20                  25                  30

 Pro Ser Pro Leu Arg Gly Asn Val Val Pro Ser Pro Leu Pro Thr
                  35                  40                  45

 Arg Arg Thr Arg Thr Phe Ser Ala Thr Val Arg Ala Ser Gln Val
                  50                  55                  60

 Pro Val Tyr Lys Gly Val Cys Lys Cys Phe Cys Arg Ser Lys Gly
                  65                  70                  75

 His Gly Phe Ile Thr Pro Ala Asp Gly Gly Pro Asp Ile Phe Leu
                  80                  85                  90

 His Ile Ser Asp Val Glu Gly Glu Tyr Val Pro Val Glu Gly Asp
                  95                 100                 105

 Glu Val Thr Tyr Lys Met Cys Ser Ile Pro Pro Lys Asn Glu Lys
                 110                 115                 120

 Leu Gln Ala Val Glu Val Val Ile Thr His Leu Ala Pro Gly Thr
                 125                 130                 135

 Lys His Glu Thr Trp Ser Gly His Val Ile Ser Ser
                 140                 145

<210> 3213
<211> 3443
<212> DNA
<213> Homo sapien

<400> 3213
 ttgatgctct aaatgcagaa ttaatggaga cttcaatgac tgatatgtca 50

 attcttagtt tctttgaaca tttccatatt tctcctgtga agttgcattt 100

 gagtttgtct ttgggttccg gaggtgaaga atcagacaaa gaaaaacagg 150

 aaatgtttgc agttcattct gtcaacttgc tgttgaagag cataggtgct 200

 actctgactg atgtggatga ccttatattc aaacttgctt attatgaaat 250

 tcgatatcag ttctacaaga gagatcagct tatatggagt gttgttaggc 300

 attacagtga acagttcttg aaacagatgt atgtccttgt attggggtta 350

 gatgtacttg gaaacccatt tggattaatt agaggtctgt ctgaaggagt 400

 tgaagcttta ttctatgaac ccttccaggg tgctgttcaa ggccctgaag 450

 aatttgcaga ggggttagtg attggagtga gaagcctctt tggacacaca 500

 gtaggtggtg cagcaggagt tgtatctcga atcaccggtt ctgttgggaa 550

 aggtttggca gcaattacaa tggacaagga atatcagcaa aaaagaagag 600

 aagagttgag tcgacagccc agagattttg gagacagcct ggccagagga 650

 ggaaagggct ttctgcgagg agttgttggt ggagtgactg gaataataac 700

 aaaacctgtg gaaggtgcca aaaaggaagg agctgctgga ttctttaaag 750

 gaattggaaa agggcttgtg ggtgctgtgg cccgtccaac tggtggaatc 800

 gtagatatgg ccagtagtac cttccaaggc attcagaggg cagcagaatc 850

 aactgaggaa gtatctagcc tccgtccccc tcgcctgatc catgaagatg 900

 gcatcattcg tccttatgac agacaggaat ctgagggctc tgacttactt 950

 gagaatcata tcaaaaagtt ggaaggagag acttaccgat accactgtgc 1000

 tattcctgga agcaagaaga caatccttat ggttacaaat aggcgagtgt 1050

 tgtgtataaa ggaagttgaa atcctgggcc ttatgtgtgt agactggcaa 1100

 tgtccatttg aagattttgt atttcctcct agtgtcagtg aaaatgtgct 1150

 aaaaatttca gttaaggaac agggtctgtt ccacaaaaaa gacagtgcca 1200

 atcaaggctg tgttcgaaaa gtttacctga aggacaccgc cacagcagag 1250

 agagcatgta atgccattga ggatgcacag tcaacgagac agcagcaaaa 1300

 attgatgaag cagtcatcag tgagacttct cagaccccaa ttgccatctt 1350

 aatcacagac ctcaggggct ccaacaggga gaaaaaacaa tcactggtct 1400

 tgtctataag tcactctgct ttatcttgct aaagacaatt tttcaagcaa 1450

 tcctttagtt ttagttttct ggaatagcta gtattgggtt ttctagtttt 1500

 ttcacctttt agtttttact ctaattttgt aaccatgtat atgctagcag 1550

 tccacttcta cgccaccacc caaatgggtc agacccttga agaaacgtca 1600

 cttcaaactc agaatgaaat tttcattaat attaaaattg tgaagcaaag 1650

 gtcaataggc ttatatttaa ttaaagcctt actgaagaat aagaaatgag 1700

 cttagaatga ctagtgttct ttgaaaggtt tttttatttt tgtttttttg 1750

 gggttttttt tttttttttt gagaccgagt cttgctctgt cgcccaggct 1800

 ggaatgcagt ggtgcgatct tggctcactg caatctctgc ctctcgggtt 1850

 caagcggttc tactgcctca gcctcctgag tagctaggat tacaggtgtg 1900

 tgccaccacg cctgggtaat tttttttttt tttgtatttt tagtagagat 1950

 gagtttcacc atgttggtca gtctagtctc gaactcctga ccttgtgatc 2000

 cgcatgcctc agcctcccaa agtgctggga ttacaggcat gagccaccac 2050

 ggcccgccaa aaggctttaa cccatgaaca aatgttggat cctgacattt 2100

 tgtttaagag tgatttgttc aataattgaa ctgagttaac attcttggta 2150

 aaccaggtaa ttgaatgaag aaaggtcact aaagggagaa atgacatgtt 2200

 ttctattttc ttttcatgaa aacactgttt ttccccctaa taaagcatat 2250

 tttactttgg tgcttatttt tcctccttgc agtctaataa aaaaatctgg 2300

 acaatcaaac cttaaaatag ctacactctg ccctctgtaa tgtagcattc 2350

 ataaaaattt ggaagtattt acatcctctt tcaagatgag cttatatgac 2400

 acaattatta tttgctgata catgaaaata ctgcacttta agtttctcaa 2450

 gactctgaaa tatgtaaaat tcaatatttt tatattccca gaaattgttt 2500

 cttacaggtt gaaagtcttt taagggcatc acaaattaac atttactcct 2550

 aatgcacgcc tagaatgtat tttaaatact tactaagaag aatgaaaatt 2600

 ctttggttgt tttatatata aataaggcat atataatgac actgtgttct 2650

 gtgagggagc aggccctgtg agaatcaatt caggacagta tttttttttg 2700

 tcctttctcc atccttgatc agagataaac tattaaaact ttaaaaaata 2750

 ctcaaaaata tgtaagtttt ttggttgaac ctttagattt gctcataatg 2800

 tttaacataa caacatttat ttcaaatcac tgaattcatg gagatgtgga 2850

 cacgcttggt ttgctctatt tttgtttatg tgtgatagtg gttctgtcat 2900

 catcattcat gttttttaag gcctggtcat aaaactttaa attttactag 2950

 tgttacttaa tgtatattct aaaaagagaa tgcagtaact aatgccctaa 3000

 atgtttgatc tctgtttgtc attacttttt caaaattatt tttttctgta 3050

 aagtataata tataaaactt cttgcttaaa ttgaatttct atattagtgg 3100

 ttaattgcag tttattaaag ggatcattat cagtaatttc atagcaactg 3150

 ttctagtgtt ttgtgttttt aaaacagaat taggaatttg agatatctga 3200

 ttatattttt catatgaatc acagctgttg acaatgtccc atatatttaa 3250

 gaaattatat catactgata ctatttgtaa cattttgatt tgatttaatc 3300

 tccagggaca gaaataattc attggtaaag tgtaataatg cgttttttaa 3350

 aaatgctttg agaggtaatt acttgcatat gagagaaata aaacatttgg 3400

 cacattgttt acaggtgtga aaaaaaaaaa aaaaaaaaaa aaa 3443

<210> 3214
<211> 442
<212> PRT
<213> Homo sapien

<400> 3214
 Met Glu Thr Ser Met Thr Asp Met Ser Ile Leu Ser Phe Phe Glu
   1               5                  10                  15

 His Phe His Ile Ser Pro Val Lys Leu His Leu Ser Leu Ser Leu
                  20                  25                  30

 Gly Ser Gly Gly Glu Glu Ser Asp Lys Glu Lys Gln Glu Met Phe
                  35                  40                  45

 Ala Val His Ser Val Asn Leu Leu Leu Lys Ser Ile Gly Ala Thr
                  50                  55                  60

 Leu Thr Asp Val Asp Asp Leu Ile Phe Lys Leu Ala Tyr Tyr Glu
                  65                  70                  75

 Ile Arg Tyr Gln Phe Tyr Lys Arg Asp Gln Leu Ile Trp Ser Val
                  80                  85                  90

 Val Arg His Tyr Ser Glu Gln Phe Leu Lys Gln Met Tyr Val Leu
                  95                 100                 105

 Val Leu Gly Leu Asp Val Leu Gly Asn Pro Phe Gly Leu Ile Arg
                 110                 115                 120

 Gly Leu Ser Glu Gly Val Glu Ala Leu Phe Tyr Glu Pro Phe Gln
                 125                 130                 135

 Gly Ala Val Gln Gly Pro Glu Glu Phe Ala Glu Gly Leu Val Ile
                 140                 145                 150

 Gly Val Arg Ser Leu Phe Gly His Thr Val Gly Gly Ala Ala Gly
                 155                 160                 165

 Val Val Ser Arg Ile Thr Gly Ser Val Gly Lys Gly Leu Ala Ala
                 170                 175                 180

 Ile Thr Met Asp Lys Glu Tyr Gln Gln Lys Arg Arg Glu Glu Leu
                 185                 190                 195

 Ser Arg Gln Pro Arg Asp Phe Gly Asp Ser Leu Ala Arg Gly Gly
                 200                 205                 210

 Lys Gly Phe Leu Arg Gly Val Val Gly Gly Val Thr Gly Ile Ile
                 215                 220                 225

 Thr Lys Pro Val Glu Gly Ala Lys Lys Glu Gly Ala Ala Gly Phe
                 230                 235                 240

 Phe Lys Gly Ile Gly Lys Gly Leu Val Gly Ala Val Ala Arg Pro
                 245                 250                 255

 Thr Gly Gly Ile Val Asp Met Ala Ser Ser Thr Phe Gln Gly Ile
                 260                 265                 270

 Gln Arg Ala Ala Glu Ser Thr Glu Glu Val Ser Ser Leu Arg Pro
                 275                 280                 285

 Pro Arg Leu Ile His Glu Asp Gly Ile Ile Arg Pro Tyr Asp Arg
                 290                 295                 300

 Gln Glu Ser Glu Gly Ser Asp Leu Leu Glu Asn His Ile Lys Lys
                 305                 310                 315

 Leu Glu Gly Glu Thr Tyr Arg Tyr His Cys Ala Ile Pro Gly Ser
                 320                 325                 330

 Lys Lys Thr Ile Leu Met Val Thr Asn Arg Arg Val Leu Cys Ile
                 335                 340                 345

 Lys Glu Val Glu Ile Leu Gly Leu Met Cys Val Asp Trp Gln Cys
                 350                 355                 360

 Pro Phe Glu Asp Phe Val Phe Pro Pro Ser Val Ser Glu Asn Val
                 365                 370                 375

 Leu Lys Ile Ser Val Lys Glu Gln Gly Leu Phe His Lys Lys Asp
                 380                 385                 390

 Ser Ala Asn Gln Gly Cys Val Arg Lys Val Tyr Leu Lys Asp Thr
                 395                 400                 405

 Ala Thr Ala Glu Arg Ala Cys Asn Ala Ile Glu Asp Ala Gln Ser
                 410                 415                 420

 Thr Arg Gln Gln Gln Lys Leu Met Lys Gln Ser Ser Val Arg Leu
                 425                 430                 435

 Leu Arg Pro Gln Leu Pro Ser
                 440

<210> 3215
<211> 1645
<212> DNA
<213> Homo sapien

<400> 3215
 gcgggagagc gcagcgtcga ccctttgtgg acgccgagtg gcggtcgctc 50

 gccccgcccc gcgccgtcgg gcgctccttc ctcagcggcg ggaagctggc 100

 ggcagcggcg gtggcggtgg ctgagcagag gacccggcgg gcggcctcgc 150

 gggtcaggac acaatgtttg cacgaggact gaagaggaaa tgtgttggcc 200

 acgaggaaga cgtggaggga gccctggccg gcttgaagac agtgtcctca 250

 tacagcctgc agcggcagtc gctcctggac atgtctctgg tgaagttgca 300

 gctttgccac atgcttgtgg agcccaatct gtgccgctca gtcctcattg 350

 ccaacacggt ccggcagatc caagaggaga tgacgcagga tgggacgtgg 400

 cgcacagtgg caccccaggc tgcagagcgg gcgccgctcg accgcttggt 450

 ctccacggag atcctgtgcc gtgcagcgtg ggggcaagag ggggcacatc 500

 ctgctcctgg cttgggggac ggccacacac agggtccagt ttctgacctt 550

 tgcccagtca cctcagcaca ggcaccaagg cacctgcaga gcagcgcctg 600

 ggagatggat ggccctcgag aaaacagagg aagctttcac aagtcacttg 650

 atcagatatt tgaaacgctg gagactaaaa accccagctg catggaagag 700

 ctgttctcag acgtggacag cccctactac gacctggaca cagtactgac 750

 aggcatgatg gggggtgcca ggccgggccc ctgcgaaggg ctcgagggct 800

 tggctccggc caccccaggc cctagctcca gctgcaagtc cgacctgggc 850

 gagctggacc acgtggtgga gatcctggtg gagacctgag caggagccct 900

 gagtgctcac agccgcctct gacgcattga cactgagcat cactacagtc 950

 tcagtcaaca gtgtgaatgt atcatgtttt actttaaatg tgtgtgtgat 1000

 acttcttcat tatgtcctgc gctgcagtga gacctgggtg aaaatcagga 1050

 accgcacaca gccacatctt cctagaccta agagtaaatt atggaggatt 1100

 ttatttatgt ctatttatat gtaaatgtca ttgaagacaa aggtcaaata 1150

 tttgtctgtt tgtagatcac aggcaccagt tggtcttcag ggacctcata 1200

 gcccctcggt ggtgccttct caaggcagtg ttcctggagg ctcccgtcag 1250

 ggtcagccca tgcacctgcc ctgggtgagg aagtagcatt gctgctggat 1300

 gagaaacgcc tgcgctgctc tgttagactg gtgctgaaac aaaaggttaa 1350

 ggctaggttg aagtctagaa tgaaagaaat ctgaatccat gtcattcata 1400

 accccttgat ctgtagtgtc atgggtgctg ccgcaggcag ggagtgagct 1450

 gggggtgcct gcagccttcc actcctgccc cgcctcaccc cacatgctcc 1500

 ctgtttctca tgctttctct aacttcctca ccccttaacc aaaaaggtgt 1550

 gttttctttt gtgcatatag ccattcttaa atatcagtga tgtaaacctc 1600

 actttattaa aaaattatcc agcaaacaaa aaaaaaaaaa aaaaa 1645

<210> 3216
<211> 241
<212> PRT
<213> Homo sapien

<400> 3216
 Met Phe Ala Arg Gly Leu Lys Arg Lys Cys Val Gly His Glu Glu
   1               5                  10                  15

 Asp Val Glu Gly Ala Leu Ala Gly Leu Lys Thr Val Ser Ser Tyr
                  20                  25                  30

 Ser Leu Gln Arg Gln Ser Leu Leu Asp Met Ser Leu Val Lys Leu
                  35                  40                  45

 Gln Leu Cys His Met Leu Val Glu Pro Asn Leu Cys Arg Ser Val
                  50                  55                  60

 Leu Ile Ala Asn Thr Val Arg Gln Ile Gln Glu Glu Met Thr Gln
                  65                  70                  75

 Asp Gly Thr Trp Arg Thr Val Ala Pro Gln Ala Ala Glu Arg Ala
                  80                  85                  90

 Pro Leu Asp Arg Leu Val Ser Thr Glu Ile Leu Cys Arg Ala Ala
                  95                 100                 105

 Trp Gly Gln Glu Gly Ala His Pro Ala Pro Gly Leu Gly Asp Gly
                 110                 115                 120

 His Thr Gln Gly Pro Val Ser Asp Leu Cys Pro Val Thr Ser Ala
                 125                 130                 135

 Gln Ala Pro Arg His Leu Gln Ser Ser Ala Trp Glu Met Asp Gly
                 140                 145                 150

 Pro Arg Glu Asn Arg Gly Ser Phe His Lys Ser Leu Asp Gln Ile
                 155                 160                 165

 Phe Glu Thr Leu Glu Thr Lys Asn Pro Ser Cys Met Glu Glu Leu
                 170                 175                 180

 Phe Ser Asp Val Asp Ser Pro Tyr Tyr Asp Leu Asp Thr Val Leu
                 185                 190                 195

 Thr Gly Met Met Gly Gly Ala Arg Pro Gly Pro Cys Glu Gly Leu
                 200                 205                 210

 Glu Gly Leu Ala Pro Ala Thr Pro Gly Pro Ser Ser Ser Cys Lys
                 215                 220                 225

 Ser Asp Leu Gly Glu Leu Asp His Val Val Glu Ile Leu Val Glu
                 230                 235                 240

 Thr


<210> 3217
<211> 6270
<212> DNA
<213> Homo sapien

<400> 3217
 gccctgcttc cccttgcacc tgcgccgggc ggccatggac ttgtacagca 50

 ccccggccgc tgcgctggac aggttcgtgg ccagaaggct gcagccgcgg 100

 aaggagttcg tagagaaggc gcggcgcgct ctgggcgccc tggccgctgc 150

 cctgagggag cgcgggggcc gcctcggtgc tgctgccccg cgggtgctga 200

 aaactgtcaa gggaggctcc tcgggccggg gcacagctct caagggtggc 250

 tgtgattctg aacttgtcat cttcctcgac tgcttcaaga gctatgtgga 300

 ccagagggcc cgccgtgcag agatcctcag tgagatgcgg gcatcgctgg 350

 aatcctggtg gcagaaccca gtccctggtc tgagactcac gtttcctgag 400

 cagagcgtgc ctggggccct gcagttccgc ctgacatccg tagatcttga 450

 ggactggatg gatgttagcc tggtgcctgc cttcaatgtc ctgggtcagg 500

 ccggctccgc ggtcaaaccc aagccacaag tctactctac cctcctcaac 550

 agtggctgcc aagggggcga gcatgcggcc tgcttcacag agctgcggag 600

 gaactttgtg aacattcgcc cagccaagtt gaagaaccta atcttgctgg 650

 tgaagcactg gtaccaccag gtgtgcctac aggggttgtg gaaggagacg 700

 ctgcccccgg tctatgccct ggaattgctg accatcttcg cctgggagca 750

 gggctgtaag aaggatgctt tcagcctagg cgaaggcctc cgaactgtcc 800

 tgggcctgat ccaacagcat cagcacctgt gtgttttctg gactgtcaac 850

 tatggcttcg aggaccctgc agttgggcag ttcttgcagc ggcacgttaa 900

 gagacccagg cctgtgatcc tggacccagc tgaccccaca tgggacctgg 950

 ggaatggggc agcctggcac tgggatttgc atgcccagga ggcagcatcc 1000

 tgctatgacc acccatgctt tctgaggggg atgggggacc cagtgcagtc 1050

 ttggaagggg ccgggccttc cacgtgctgg atgctcaggt ttgggccacc 1100

 ccatccagct agaccctaac cagaagaccc ctgaaaacag caagagcctc 1150

 aatgctgtgt acccaagagc agggagcaaa cctccctcat gcccagctcc 1200

 tggccccact gcggagccag catcgtaccc ctctgtgccg ggaatggcct 1250

 tggacctgtc tcagatcccc accaaggagc tggaccgctt catccaggac 1300

 cacctgaagc cgagccccca gttccaggag caggtgaaaa aggccatcga 1350

 catcatcttg cgctgcctcc atgagaactg tgttcacaag gcctcaagag 1400

 tcagtaaagg gggctcattt ggccggggca cagacctaag ggatggctgt 1450

 gatgttgaac tcatcatctt cctcaactgc ttcacggact acaaggacca 1500

 ggggccccgc cgcgcagaga tccttgatga gatgcgagcg cacgtagaat 1550

 cctggtggca ggaccaggtg cccagcctga gccttcagtt tcctgagcag 1600

 aatgtgcctg aggctctgca gttccagctg gtgtccacag ccctgaagag 1650

 ctggacggat gttagcctgc tgcctgcctt cgatgctgtg gggcagctca 1700

 gttctggcac caaaccaaat ccccaggtct actcgaggct cctcaccagt 1750

 ggctgccagg agggcgagca taaggcctgc ttcgcagagc tgcggaggaa 1800

 cttcatgaac attcgccctg tcaagctgaa gaacctgatt ctgctggtga 1850

 agcactggta ccgccaggtt gcggctcaga acaaaggaaa aggaccagcc 1900

 cctgcctctc tgcccccagc ctatgccctg gagctcctca ccatctttgc 1950

 ctgggagcag ggctgcaggc aggattgttt caacatggcc caaggcttcc 2000

 ggacggtgct ggggctcgtg caacagcatc agcagctctg tgtctactgg 2050

 acggtcaact atagcactga ggacccagcc atgagaatgc accttcttgg 2100

 ccagcttcga aaacccagac ccctggtcct ggaccccgct gatcccacct 2150

 ggaacgtggg ccacggtagc tgggagctgt tggcccagga agcagcagcg 2200

 ctggggatgc aggcctgctt tctgagtaga gacgggacat ctgtgcagcc 2250

 ctgggatgtg atgccagccc tcctttacca aaccccagct ggggaccttg 2300

 acaagttcat cagtgaattt ctccagccca accgccagtt cctggcccag 2350

 gtgaacaagg ccgttgatac catctgttca tttttgaagg aaaactgctt 2400

 ccggaattct cccatcaaag tgatcaaggt ggtcaagggt ggctcttcag 2450

 ccaaaggcac agctctgcga ggccgctcag atgccgacct cgtggtgttc 2500

 ctcagctgct tcagccagtt cactgagcag ggcaacaagc gggccgagat 2550

 catctccgag atccgagccc agctggaggc atgtcaacag gagcggcagt 2600

 tcgaggtcaa gtttgaagtc tccaaatggg agaatccccg cgtgctgagc 2650

 ttctcactga catcccagac gatgctggac cagagtgtgg actttgatgt 2700

 gctgccagcc tttgacgccc taggccagct ggtctctggc tccaggccca 2750

 gctctcaagt ctacgtcgac ctcatccaca gctacagcaa tgcgggcgag 2800

 tactccacct gcttcacaga gctacaacgg gacttcatca tctctcgccc 2850

 taccaagctg aagagcctga tccggctggt gaagcactgg taccagcagt 2900

 gtaccaagat ctccaagggg agaggctccc tacccccaca gcacgggctg 2950

 gaactcctga ctgtgtatgc ctgggagcag ggcgggaagg actcccagtt 3000

 caacatggct gagggcttcc gcacggtcct ggagctggtc acccagtacc 3050

 gccagctctg tatctactgg accatcaact acaacgccaa ggacaagact 3100

 gttggagact tcctgaaaca gcagcttcag aagcccaggc ctatcatcct 3150

 ggatccggct gacccgacag gcaacctggg ccacaatgcc cgctgggacc 3200

 tgctggccaa ggaagctgca gcctgcacat ctgccctgtg ctgcatggga 3250

 cggaatggca tccccatcca gccatggcca gtgaaggctg ctgtgtgaag 3300

 ttgagaaaat cagcggtcct actggatgaa gagaagatgg acaccagccc 3350

 tcagcatgag gaaattcagg gtcccctacc agatgagaga gattgtgtac 3400

 atgtgtgtgt gagcacatgt gtgcatgtgt gtgcacacgt gtgcatgtgt 3450

 gtgttttagt gaatctgctc tcccagctca cacactcccc tgcctcccat 3500

 ggcttacaca ctaggatcca gactccatgg tttgacacca gcctgcgttt 3550

 gcagcttctc tgtcacttcc atgactctat cctcatacca ccactgctgc 3600

 ttcccaccca gctgagaatg ccccctcctc cctgactcct ctctgcccat 3650

 gcaaattagc tcacatcttt cctcctgctg caatccatcc cttcctccca 3700

 ttggcctctc cttgccaaat ctaaatactt tatataggga tggcagagag 3750

 ttcccatctc atctgtcagc cacagtcatt tggtactggc tacctggagc 3800

 cttatcttct gaagggtttt aaagaatggc caattagctg agaagaatta 3850

 tctaatcaat tagtgatgtc tgccatggat gcagtagagg aaagtggtgg 3900

 tacaagtgcc atgattgatt agcaatgtct gcactggata tggaaaaaag 3950

 aaggtgcttg caggtttaca gtgtatatgt gggctattga agagccctct 4000

 gagctcggtt gctagcagga gagcatgccc atattggctt actttgtctg 4050

 ccacagacac agacagaggg agttgggaca tgcatgctat ggggaccctc 4100

 ttgttggaca cctaattgga tgcctcttca tgagaggcct ccttttcttc 4150

 accttttatg ctgcactcct cccctagttt acacatcttg atgctgtggc 4200

 tcagtttgcc ttcctgaatt tttattgggt ccctgttttc tctcctaaca 4250

 tgctgagatt ctgcatcccc acagcctaaa ctgagccagt ggccaaacaa 4300

 ccgtgctcag cctgtttctc tctgccctct agagcaaggc ccaccaggtc 4350

 catccaggag gctctcctga cctcaagtcc aacaacagtg tccacactag 4400

 tcaaggttca gcccagaaaa cagaaagcac tctaggaatc ttaggcagaa 4450

 agggatttta tctaaatcac tggaaaggct ggaggagcag aaggcagagg 4500

 ccaccactgg actattggtt tcaatattag accactgtag ccgaatcaga 4550

 ggccagagag cagccactgc tactgctaat gccaccacta cccctgccat 4600

 cactgcccca catggacaaa actggagtcg agacctaggt tagattcctg 4650

 caaccacaaa catccatcag ggatggccag ctgccagagc tgcgggaaga 4700

 cggatcccac ctccctttct tagcagaatc taaattacag ccagacctct 4750

 ggctgcagag gagtctgaga catgtatgat tgaatgggtg ccaagtgcca 4800

 gggggcggag tccccagcag atgcatcctg gccatctgtt gcgtggatga 4850

 gggagtgggt ctatctcaga ggaaggaaca ggaaacaaag aaaggaagcc 4900

 actgaacatc ccttctctgc tccacaggag tgtcttagac agcctgactc 4950

 tccacaaacc actgttaaaa cttacctgct aggaatgcta gattgaatgg 5000

 gatgggaaga gccttccctc attattgtca ttcttggaga gaggtgagca 5050

 accaagggaa gctcctctga ttcacctaga acctgttctc tgccgtcttt 5100

 ggctcagcct acagagacta gagtaggtga agggacagag gacagggctt 5150

 ctaatacctg tgccatattg acagcctcca tccctgtccc ccatcttggt 5200

 gctgaaccaa cgctaagggc accttcttag actcacctca tcgatactgc 5250

 ctggtaatcc aaagctagaa ctctcaggac cccaaactcc acctcttgga 5300

 ttggccctgg ctgctgccac acacatatcc aagagctcag ggccagttct 5350

 ggtgggcagc agagacctgc tctgccaagt tgtccagcag cagagtggcc 5400

 ctggcctggg catcacaagc cagtgatgct cctgggaaga ccaggtggca 5450

 ggtcgcagtt gggtaccttc cattcccacc acacagactc tgggcctccc 5500

 cgcaaaatgg ctccagaatt agagtaatta tgagatggtg ggaaccagag 5550

 caactcaggt gcatgataca aggagaggtt gtcatctggg tagggcagag 5600

 aggagggctt gctcatctga acaggggtgt atttcattcc aggccctcag 5650

 tctttggcaa tggccaccct ggtgttggca tattggcccc actgtaactt 5700

 ttgggggctt cccggtctag ccacaccctc ggatggaaag acttgactgc 5750

 ataaagatgt cagttctccc tgagttgatt gataggctta atggtcaccc 5800

 taaaaacacc cacatatgct tttcgatgga accagataag ttgacgctaa 5850

 agttcttatg gaaaaataca cacgcaatag ctaggaaaac acagggaaag 5900

 aagagttctg agcagggcct agtcttagcc aatattaaaa catactatga 5950

 agcctctgat acttaaacag catggcgctg gtacgtaaat agaccaatgc 6000

 agttaggtgg ctctttccaa gactctgggg aaaaaagtag taaaaagcta 6050

 aatgcaatca atcagcaatt gaaagctaag tgagagagcc agagggcctc 6100

 cttggtggta aaagagggtt gcatttcttg cagccagaag gcagagaaag 6150

 tgaagaccaa gtccagaact gaatcctaag aaatgcagga ctgcaaagaa 6200

 attggtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtttaa tttttaaaaa 6250

 gtttttattc ggaatccgcg 6270

<210> 3218
<211> 1087
<212> PRT
<213> Homo sapien

<400> 3218
 Met Asp Leu Tyr Ser Thr Pro Ala Ala Ala Leu Asp Arg Phe Val
   1               5                  10                  15

 Ala Arg Arg Leu Gln Pro Arg Lys Glu Phe Val Glu Lys Ala Arg
                  20                  25                  30

 Arg Ala Leu Gly Ala Leu Ala Ala Ala Leu Arg Glu Arg Gly Gly
                  35                  40                  45

 Arg Leu Gly Ala Ala Ala Pro Arg Val Leu Lys Thr Val Lys Gly
                  50                  55                  60

 Gly Ser Ser Gly Arg Gly Thr Ala Leu Lys Gly Gly Cys Asp Ser
                  65                  70                  75

 Glu Leu Val Ile Phe Leu Asp Cys Phe Lys Ser Tyr Val Asp Gln
                  80                  85                  90

 Arg Ala Arg Arg Ala Glu Ile Leu Ser Glu Met Arg Ala Ser Leu
                  95                 100                 105

 Glu Ser Trp Trp Gln Asn Pro Val Pro Gly Leu Arg Leu Thr Phe
                 110                 115                 120

 Pro Glu Gln Ser Val Pro Gly Ala Leu Gln Phe Arg Leu Thr Ser
                 125                 130                 135

 Val Asp Leu Glu Asp Trp Met Asp Val Ser Leu Val Pro Ala Phe
                 140                 145                 150

 Asn Val Leu Gly Gln Ala Gly Ser Ala Val Lys Pro Lys Pro Gln
                 155                 160                 165

 Val Tyr Ser Thr Leu Leu Asn Ser Gly Cys Gln Gly Gly Glu His
                 170                 175                 180

 Ala Ala Cys Phe Thr Glu Leu Arg Arg Asn Phe Val Asn Ile Arg
                 185                 190                 195

 Pro Ala Lys Leu Lys Asn Leu Ile Leu Leu Val Lys His Trp Tyr
                 200                 205                 210

 His Gln Val Cys Leu Gln Gly Leu Trp Lys Glu Thr Leu Pro Pro
                 215                 220                 225

 Val Tyr Ala Leu Glu Leu Leu Thr Ile Phe Ala Trp Glu Gln Gly
                 230                 235                 240

 Cys Lys Lys Asp Ala Phe Ser Leu Gly Glu Gly Leu Arg Thr Val
                 245                 250                 255

 Leu Gly Leu Ile Gln Gln His Gln His Leu Cys Val Phe Trp Thr
                 260                 265                 270

 Val Asn Tyr Gly Phe Glu Asp Pro Ala Val Gly Gln Phe Leu Gln
                 275                 280                 285

 Arg His Val Lys Arg Pro Arg Pro Val Ile Leu Asp Pro Ala Asp
                 290                 295                 300

 Pro Thr Trp Asp Leu Gly Asn Gly Ala Ala Trp His Trp Asp Leu
                 305                 310                 315

 His Ala Gln Glu Ala Ala Ser Cys Tyr Asp His Pro Cys Phe Leu
                 320                 325                 330

 Arg Gly Met Gly Asp Pro Val Gln Ser Trp Lys Gly Pro Gly Leu
                 335                 340                 345

 Pro Arg Ala Gly Cys Ser Gly Leu Gly His Pro Ile Gln Leu Asp
                 350                 355                 360

 Pro Asn Gln Lys Thr Pro Glu Asn Ser Lys Ser Leu Asn Ala Val
                 365                 370                 375

 Tyr Pro Arg Ala Gly Ser Lys Pro Pro Ser Cys Pro Ala Pro Gly
                 380                 385                 390

 Pro Thr Ala Glu Pro Ala Ser Tyr Pro Ser Val Pro Gly Met Ala
                 395                 400                 405

 Leu Asp Leu Ser Gln Ile Pro Thr Lys Glu Leu Asp Arg Phe Ile
                 410                 415                 420

 Gln Asp His Leu Lys Pro Ser Pro Gln Phe Gln Glu Gln Val Lys
                 425                 430                 435

 Lys Ala Ile Asp Ile Ile Leu Arg Cys Leu His Glu Asn Cys Val
                 440                 445                 450

 His Lys Ala Ser Arg Val Ser Lys Gly Gly Ser Phe Gly Arg Gly
                 455                 460                 465

 Thr Asp Leu Arg Asp Gly Cys Asp Val Glu Leu Ile Ile Phe Leu
                 470                 475                 480

 Asn Cys Phe Thr Asp Tyr Lys Asp Gln Gly Pro Arg Arg Ala Glu
                 485                 490                 495

 Ile Leu Asp Glu Met Arg Ala His Val Glu Ser Trp Trp Gln Asp
                 500                 505                 510

 Gln Val Pro Ser Leu Ser Leu Gln Phe Pro Glu Gln Asn Val Pro
                 515                 520                 525

 Glu Ala Leu Gln Phe Gln Leu Val Ser Thr Ala Leu Lys Ser Trp
                 530                 535                 540

 Thr Asp Val Ser Leu Leu Pro Ala Phe Asp Ala Val Gly Gln Leu
                 545                 550                 555

 Ser Ser Gly Thr Lys Pro Asn Pro Gln Val Tyr Ser Arg Leu Leu
                 560                 565                 570

 Thr Ser Gly Cys Gln Glu Gly Glu His Lys Ala Cys Phe Ala Glu
                 575                 580                 585

 Leu Arg Arg Asn Phe Met Asn Ile Arg Pro Val Lys Leu Lys Asn
                 590                 595                 600

 Leu Ile Leu Leu Val Lys His Trp Tyr Arg Gln Val Ala Ala Gln
                 605                 610                 615

 Asn Lys Gly Lys Gly Pro Ala Pro Ala Ser Leu Pro Pro Ala Tyr
                 620                 625                 630

 Ala Leu Glu Leu Leu Thr Ile Phe Ala Trp Glu Gln Gly Cys Arg
                 635                 640                 645

 Gln Asp Cys Phe Asn Met Ala Gln Gly Phe Arg Thr Val Leu Gly
                 650                 655                 660

 Leu Val Gln Gln His Gln Gln Leu Cys Val Tyr Trp Thr Val Asn
                 665                 670                 675

 Tyr Ser Thr Glu Asp Pro Ala Met Arg Met His Leu Leu Gly Gln
                 680                 685                 690

 Leu Arg Lys Pro Arg Pro Leu Val Leu Asp Pro Ala Asp Pro Thr
                 695                 700                 705

 Trp Asn Val Gly His Gly Ser Trp Glu Leu Leu Ala Gln Glu Ala
                 710                 715                 720

 Ala Ala Leu Gly Met Gln Ala Cys Phe Leu Ser Arg Asp Gly Thr
                 725                 730                 735

 Ser Val Gln Pro Trp Asp Val Met Pro Ala Leu Leu Tyr Gln Thr
                 740                 745                 750

 Pro Ala Gly Asp Leu Asp Lys Phe Ile Ser Glu Phe Leu Gln Pro
                 755                 760                 765

 Asn Arg Gln Phe Leu Ala Gln Val Asn Lys Ala Val Asp Thr Ile
                 770                 775                 780

 Cys Ser Phe Leu Lys Glu Asn Cys Phe Arg Asn Ser Pro Ile Lys
                 785                 790                 795

 Val Ile Lys Val Val Lys Gly Gly Ser Ser Ala Lys Gly Thr Ala
                 800                 805                 810

 Leu Arg Gly Arg Ser Asp Ala Asp Leu Val Val Phe Leu Ser Cys
                 815                 820                 825

 Phe Ser Gln Phe Thr Glu Gln Gly Asn Lys Arg Ala Glu Ile Ile
                 830                 835                 840

 Ser Glu Ile Arg Ala Gln Leu Glu Ala Cys Gln Gln Glu Arg Gln
                 845                 850                 855

 Phe Glu Val Lys Phe Glu Val Ser Lys Trp Glu Asn Pro Arg Val
                 860                 865                 870

 Leu Ser Phe Ser Leu Thr Ser Gln Thr Met Leu Asp Gln Ser Val
                 875                 880                 885

 Asp Phe Asp Val Leu Pro Ala Phe Asp Ala Leu Gly Gln Leu Val
                 890                 895                 900

 Ser Gly Ser Arg Pro Ser Ser Gln Val Tyr Val Asp Leu Ile His
                 905                 910                 915

 Ser Tyr Ser Asn Ala Gly Glu Tyr Ser Thr Cys Phe Thr Glu Leu
                 920                 925                 930

 Gln Arg Asp Phe Ile Ile Ser Arg Pro Thr Lys Leu Lys Ser Leu
                 935                 940                 945

 Ile Arg Leu Val Lys His Trp Tyr Gln Gln Cys Thr Lys Ile Ser
                 950                 955                 960

 Lys Gly Arg Gly Ser Leu Pro Pro Gln His Gly Leu Glu Leu Leu
                 965                 970                 975

 Thr Val Tyr Ala Trp Glu Gln Gly Gly Lys Asp Ser Gln Phe Asn
                 980                 985                 990

 Met Ala Glu Gly Phe Arg Thr Val Leu Glu Leu Val Thr Gln Tyr
                 995                1000                1005

 Arg Gln Leu Cys Ile Tyr Trp Thr Ile Asn Tyr Asn Ala Lys Asp
                1010                1015                1020

 Lys Thr Val Gly Asp Phe Leu Lys Gln Gln Leu Gln Lys Pro Arg
                1025                1030                1035

 Pro Ile Ile Leu Asp Pro Ala Asp Pro Thr Gly Asn Leu Gly His
                1040                1045                1050

 Asn Ala Arg Trp Asp Leu Leu Ala Lys Glu Ala Ala Ala Cys Thr
                1055                1060                1065

 Ser Ala Leu Cys Cys Met Gly Arg Asn Gly Ile Pro Ile Gln Pro
                1070                1075                1080

 Trp Pro Val Lys Ala Ala Val
                1085

<210> 3219
<211> 2591
<212> DNA
<213> Homo sapien

<400> 3219
 gctgagcgcg ggcgcggggc cgctacgtgc gcggggagcg cggggagcgc 50

 ggggagcgcg gggctgcgct cgtgtgcgct cctgggcgct cgccgccgcc 100

 gctgccgccg cgcgcctttg agtcagcaaa ctccgcggcc cgcaagcccg 150

 gctcggcccg gccctgctct gttctgcccg gaggagccgc ccattgatcg 200

 tgtcctgtgc tgaagatgtt tccggaacaa cagaaagagg aatttgtaag 250

 tgtctgggtt cgagatccta ggattcagaa ggaggacttc tggcattctt 300

 acattgacta tgagatatgt attcatacta atagcatgtg ttttacaatg 350

 aaaacatcct gtgtacgaag aagatataga gaattcgtgt ggctgaggca 400

 gagactccaa agtaatgcgt tgctggtaca actgccagaa cttccatcta 450

 aaaacctgtt tttcaacatg aacaatcgcc agcacgtgga tcagcgtcgc 500

 cagggtctgg aagatttcct cagaaaagtc ctacagaatg cacttttgct 550

 ttcagatagc agccttcacc tcttcttaca gagccatctg aattcagaag 600

 acattgaggc gtgtgtttct gggcagacta agtactctgt ggaagaagca 650

 attcacaagt ttgccttaat gaatagacgt ttccctgaag aagatgaaga 700

 aggaaaaaaa gaaaatgata tagattatga ttcagaaagt tcatcctctg 750

 ggcttggaca cagtagtgat gacagcagtt cacatggatg taaagtaaat 800

 acagctccgc aggaatcctg aaaaataatt ctaatgttac tatcttagga 850

 atagcaaatt atgtccagtc atagagaaga aagcttcata ataatacatt 900

 cttacctaaa gctcactgtc atgatgttag gtatttaaat tcttaaagat 950

 gttgggttgt ttattagtgg tatttttatg ttgtcttatt ttaggtaagc 1000

 ttctgtgtaa agctaaaaat cctgtgaata caatactatc ctttacaggc 1050

 agacattatt ggtaaacaag atcttgccct ccaatgaaat gacttacatg 1100

 ttttaaaaaa ccgagttggt tttattgaat ttaaaaagat aggtaactaa 1150

 gtagcattta aaatcaagat agagcattcc ttcttgtatc agtggggcag 1200

 tgttaccata aacacggtgt atatgttgtt aaaccctatg aagagtaaca 1250

 gtgtagacca gactgcctct ctcagatatg tgcctgatat tttgtggata 1300

 cctcccctgc actggcaaaa cactatgctt ttgggtgtta gactgaaata 1350

 ttttaagagt atttaacctt tccagtattc tgtttcacgc ttagatggaa 1400

 atgtatctta tgaatagaga catattaaaa taatgtttac atcttagaaa 1450

 aaacatagat agtgctagta atattactta taactgtaat atatagattc 1500

 agaaatacat tttcattatc caaaatcagc ttcaacaaat ggtttctgga 1550

 gacaaataat ttgttttcat tatcattgta taatcaggtt aatgatttat 1600

 tttttgacta aatgtgcaat ttcttatcac tagataactt tcagtatcag 1650

 tggtggttac ttattactta aatcagagga aggattttat aaagattaat 1700

 aaatttaatt ttaccaataa atattcccat aatttagaaa aggatgtcga 1750

 cttgctaatt tcagaaataa ttattcattt ttaaaaagcc ccttttaaag 1800

 catctacttg aagattggta taattttcat aaaatgtctt tttttttagt 1850

 gtcccaaaga tatcttagat aaactatttt gaagttcaga tttcagatga 1900

 ggcaacattt tcttgagata attacccaag tttcatccat gttgaatggt 1950

 acaaaatatt tctgtgaaac taacaggaag atattttcag ataactagga 2000

 taacttgttg ctttgttacc cagcctaatt gaagagtggc agaggctact 2050

 acaaaaagca accttttcat tttcactaag agtttaaaag ctattgtatt 2100

 attaaaaagt ctttacaatg cttgtttcaa agaaccaaca gaaaaaaaag 2150

 ctaagaaaac tgagaactaa cattaaaaaa attaaattta gaataagaat 2200

 gatttcttta atttgtcctt tttttctttg gtctaaaaca ttattaaatt 2250

 tttgtaaata ttttgattta atgtgtctta gatcctcatt attttaatac 2300

 aggaaaagaa aagatttagt aatttcttac catgctaata tgtaaagttc 2350

 atgccatcca ggcatttaag agcgatcctc atcccttcag caatatgtat 2400

 ttgagttcac actatttctg ttttacagca gttttgaaaa acacatacta 2450

 tgccaccaat tgtcatatta tttttagatg atgtaacata gccatcaaaa 2500

 ttaatattat gtaatgccta atacttagta tgtaaatgtc acgagatcat 2550

 ttttacatta aacgtgaaaa aaaatcaaaa aaaaaaaaaa a 2591

<210> 3220
<211> 201
<212> PRT
<213> Homo sapien

<400> 3220
 Met Phe Pro Glu Gln Gln Lys Glu Glu Phe Val Ser Val Trp Val
   1               5                  10                  15

 Arg Asp Pro Arg Ile Gln Lys Glu Asp Phe Trp His Ser Tyr Ile
                  20                  25                  30

 Asp Tyr Glu Ile Cys Ile His Thr Asn Ser Met Cys Phe Thr Met
                  35                  40                  45

 Lys Thr Ser Cys Val Arg Arg Arg Tyr Arg Glu Phe Val Trp Leu
                  50                  55                  60

 Arg Gln Arg Leu Gln Ser Asn Ala Leu Leu Val Gln Leu Pro Glu
                  65                  70                  75

 Leu Pro Ser Lys Asn Leu Phe Phe Asn Met Asn Asn Arg Gln His
                  80                  85                  90

 Val Asp Gln Arg Arg Gln Gly Leu Glu Asp Phe Leu Arg Lys Val
                  95                 100                 105

 Leu Gln Asn Ala Leu Leu Leu Ser Asp Ser Ser Leu His Leu Phe
                 110                 115                 120

 Leu Gln Ser His Leu Asn Ser Glu Asp Ile Glu Ala Cys Val Ser
                 125                 130                 135

 Gly Gln Thr Lys Tyr Ser Val Glu Glu Ala Ile His Lys Phe Ala
                 140                 145                 150

 Leu Met Asn Arg Arg Phe Pro Glu Glu Asp Glu Glu Gly Lys Lys
                 155                 160                 165

 Glu Asn Asp Ile Asp Tyr Asp Ser Glu Ser Ser Ser Ser Gly Leu
                 170                 175                 180

 Gly His Ser Ser Asp Asp Ser Ser Ser His Gly Cys Lys Val Asn
                 185                 190                 195

 Thr Ala Pro Gln Glu Ser
                 200

<210> 3221
<211> 4350
<212> DNA
<213> Homo sapien

<400> 3221
 gtcggtgcct gcagggctct ccgtgcccgc tcgggagagg tgctcttcgc 50

 tcaggctccc ccggagactt gagggggtgc gcgctggcgt gcatggggcc 100

 tgttctgtcc ttggtttggg gatgctccta aggggggaga aagggatacc 150

 tcgggtgctt ggaggtcgag agacggatac gtaagtgcgc aagggccact 200

 gattagggca cgggaagggc tcgctagaat gagctcttaa actggttggg 250

 tgtaagcggt tttgggctag tctaaaccaa acaactgaga ataaacgcgg 300

 ggttcctgca ggttgagaga gtacctgtct gcaaatgtcc agtagtgatg 350

 gattgccttg taggccccag agcaatcggg gaagttagca ttcttgttca 400

 agaagctgct ggttcactta gagctataaa agaatgttgt gagtttggat 450

 tttcttccaa acgttcagga ttgaggttag ggctggtggt gagggatcat 500

 gtaaagaggt ttgagtggct cagccttagg tcccggtgtg gaaagcttat 550

 tcttttggtg tcatcacgtg gccatgggaa ttatttagaa tgtgatctgc 600

 cctcatgaga agaaaggagc tctgaagccg ttgcagttct tcctccctat 650

 gtggaaaatc gaatttctgg aaacatcctc cgtattggga gattttgcct 700

 atgtaaaggc tatccttatt ggctagcggc actaattact ttaaaagtag 750

 gatggaagta caagtatctc aagcatcatt gggtttcgag ctcacttctg 800

 tggaaaagag tttaagggag tggtctagac tttccaggga agttattgcc 850

 tggctgtgtc cctctagtcc taattttata cttaactttc ccccacctcc 900

 ttcagcctca tctgtttcaa tggtgcaact cttttcatcc ccttttggtt 950

 accagtcacc ttcaggccat tcagaggagg aaagagaggg gaatatgaag 1000

 tcagccaagc cccaagtgaa ccacagtcag catggggaaa gccagcgggc 1050

 cttgagcccc ctgcagtcta ctctgagttc tgctgcatct ccttcccaag 1100

 cgtatgagac ctatattgaa aatggactca tatgccttaa acacaaaatt 1150

 agaaacatcg agaaaaagaa gctcaaactg gaggattata aggatcgcct 1200

 gaaaagtgga gagcatctta atccagacca gttggaagct gtagagaaat 1250

 atgaagaagt gctacataat ttggaatttg ccaaggagct tcaaaaaacc 1300

 ttttctgggt tgagcctaga tctactaaaa gcgcaaaaga aggcccagag 1350

 aagggagcac atgctaaaac ttgaggctga gaagaaaaag cttcgaacta 1400

 tacttcaagt tcagtatgta ttgcagaact tgacacagga gcacgtacaa 1450

 aaagacttca aagggggttt gaatggtgca gtgtatttgc cttcaaaaga 1500

 acttgactac ctcattaagt tttcaaaact gacctgccct gaaagaaatg 1550

 aaagtctgag tgttgaagac cagatggagc agtcatcctt gtacttttgg 1600

 gaccttttgg aaggtagtga gaaagcagtg gtaggaacga catacaaaca 1650

 cttgaaggat ctactgtcta aattgctgaa ctcaggctat tttgaaagta 1700

 tcccagttcc caaaaatgcc aaggaaaagg aagtaccact ggaggaagaa 1750

 atgctaatac aatcagagaa aaaaacacaa ttatcgaaga ctgaatctgt 1800

 caaagagtca gagtctctaa tggaatttgc ccagccagag atacaaccac 1850

 aagagtttct taacagacgc tatatgacag aagtagatta ttcaaacaaa 1900

 caaggcgaag agcaaccttg ggaagcagat tatgctagaa aaccaaatct 1950

 cccaaaacgt tgggatatgc ttactgaacc agatggtcaa gagaagaaac 2000

 aggagtcctt taagtcctgg gaggcttctg gtaagcacca ggaggtatcc 2050

 aagcctgcag tttccttaga acagaggaaa caagacacct caaaactcag 2100

 gtctactctg ccggaagagc agaagaagca ggagatctcc aaatccaagc 2150

 catctcctag ccagtggaag caagatacac ctaaatccaa agcagggtat 2200

 gttcaagagg aacaaaagaa acaggagaca ccaaagctgt ggccagttca 2250

 gctgcagaaa gaacaagatc caaagaagca aactccaaag tcttggacac 2300

 cttccatgca gagcgaacag aacaccacca agtcatggac cactcccatg 2350

 tgtgaagaac aggattcaaa acagccagag actccaaaat cctgggaaaa 2400

 caatgttgag agtcaaaaac actctttaac atcacagtca cagatttctc 2450

 caaagtcctg gggagtagct acagcaagcc tcataccaaa tgaccagctg 2500

 ctgcccagga agttgaacac agaacccaaa gatgtgccta agcctgtgca 2550

 tcagcctgta ggttcttcct ctacccttcc gaaggatcca gtattgagga 2600

 aagaaaaact gcaggatctg atgactcaga ttcaaggaac ttgtaacttt 2650

 atgcaagagt ctgttcttga ctttgacaaa ccttcaagtg caattccaac 2700

 gtcacaaccg ccttcagcta ctccaggtag ccccgtagca tctaaagaac 2750

 aaaatctgtc cagtcaaagt gattttcttc aagagccgtt acaggctact 2800

 tcttctccag ttacttgtag ctcaaatgct tgcttggtta ctaccgatca 2850

 ggcttcttct ggatctgaaa cagagtttat gacctcagag actcctgagg 2900

 tatttaacgt taatgcacct ctgcctccac gaaaagaaca agaaataaaa 2950

 gaatcccctt attcacctgg ctacaatcaa agttttacca cagcaagtac 3000

 acaaacacca ccccagtgcc aactgccatc tatacatgta gaacaaactg 3050

 tccattctca agagactgca aattatcatc ctgatggaac tattcaagta 3100

 agcaatggta gccttgcctt ttacccagca cagacgaatg tatttcccag 3150

 acctactcag ccatttgtca atagccgggg atctgttaga ggatgtactc 3200

 gtggtgggag attaataacc aattcctatc ggtcccctgg tggttataaa 3250

 ggttttgata cttacagagg actcccttca atttccaatg gaaattatag 3300

 ccagctgcag ttccaagcta gagagtattc tggagcacct tattcccaaa 3350

 gggataattt ccagcagtgt tataagcgag gagggacatc tggtggtcca 3400

 cgagcaaatt cgagagcagg gtggagtgat tcttctcagg tgagcagccc 3450

 agaaagagac aacgaaacct ttaacagtgg tgactctgga caaggagact 3500

 cccgtagcat gacccctgtg gatgtgccag tgacaaatcc agcagccacc 3550

 atactgccag tacacgtcta ccctctgcct cagcagatgc gagttgcctt 3600

 ctcagcagcc agaacctcta atctggcccc tggaacttta gaccaaccta 3650

 ttgtgtttga tcttcttctg aacaacttag gagaaacttt tgatcttcag 3700

 cttggtagat ttaattgccc agtgaatggc acttacgttt tcatttttca 3750

 catgctaaag ctggcagtga atgtgccact gtatgtcaac ctcatgaaga 3800

 atgaagaggt cttggtatca gcctatgcca atgatggtgc tccagaccat 3850

 gaaactgcta gcaatcatgc aattcttcag ctcttccagg gagaccagat 3900

 atggttacgt ctgcacaggg gagcaattta tggaagtagc tggaaatatt 3950

 ctacgttttc aggctatctt ctttatcaag attgaaagtc agtacagtat 4000

 tgacaataaa aggatggtgt tctaattagt gggattgaag gaaaagtagt 4050

 ctttgccctc atgactgatt ggtttaggaa aatgtttttg ttcctagagg 4100

 gaggaggtcc ttactttttt gttttccttc ctgaggtgaa aaatcaagct 4150

 gaatgacaat tagcactaat ctggcacttt ataaattgtg atgtagcctc 4200

 gctagtcaag ctgtgaatgt atattgtttg cacttaatcc ttaactgtat 4250

 taacgttcag cttactaaac tgactgcctc aagtccaggc aagttacaat 4300

 gccttgttgt gcctcaataa aaaagttaca tgcaaaaaaa aaaaaaaaaa 4350

<210> 3222
<211> 1077
<212> PRT
<213> Homo sapien

<400> 3222
 Met Glu Val Gln Val Ser Gln Ala Ser Leu Gly Phe Glu Leu Thr
   1               5                  10                  15

 Ser Val Glu Lys Ser Leu Arg Glu Trp Ser Arg Leu Ser Arg Glu
                  20                  25                  30

 Val Ile Ala Trp Leu Cys Pro Ser Ser Pro Asn Phe Ile Leu Asn
                  35                  40                  45

 Phe Pro Pro Pro Pro Ser Ala Ser Ser Val Ser Met Val Gln Leu
                  50                  55                  60

 Phe Ser Ser Pro Phe Gly Tyr Gln Ser Pro Ser Gly His Ser Glu
                  65                  70                  75

 Glu Glu Arg Glu Gly Asn Met Lys Ser Ala Lys Pro Gln Val Asn
                  80                  85                  90

 His Ser Gln His Gly Glu Ser Gln Arg Ala Leu Ser Pro Leu Gln
                  95                 100                 105

 Ser Thr Leu Ser Ser Ala Ala Ser Pro Ser Gln Ala Tyr Glu Thr
                 110                 115                 120

 Tyr Ile Glu Asn Gly Leu Ile Cys Leu Lys His Lys Ile Arg Asn
                 125                 130                 135

 Ile Glu Lys Lys Lys Leu Lys Leu Glu Asp Tyr Lys Asp Arg Leu
                 140                 145                 150

 Lys Ser Gly Glu His Leu Asn Pro Asp Gln Leu Glu Ala Val Glu
                 155                 160                 165

 Lys Tyr Glu Glu Val Leu His Asn Leu Glu Phe Ala Lys Glu Leu
                 170                 175                 180

 Gln Lys Thr Phe Ser Gly Leu Ser Leu Asp Leu Leu Lys Ala Gln
                 185                 190                 195

 Lys Lys Ala Gln Arg Arg Glu His Met Leu Lys Leu Glu Ala Glu
                 200                 205                 210

 Lys Lys Lys Leu Arg Thr Ile Leu Gln Val Gln Tyr Val Leu Gln
                 215                 220                 225

 Asn Leu Thr Gln Glu His Val Gln Lys Asp Phe Lys Gly Gly Leu
                 230                 235                 240

 Asn Gly Ala Val Tyr Leu Pro Ser Lys Glu Leu Asp Tyr Leu Ile
                 245                 250                 255

 Lys Phe Ser Lys Leu Thr Cys Pro Glu Arg Asn Glu Ser Leu Ser
                 260                 265                 270

 Val Glu Asp Gln Met Glu Gln Ser Ser Leu Tyr Phe Trp Asp Leu
                 275                 280                 285

 Leu Glu Gly Ser Glu Lys Ala Val Val Gly Thr Thr Tyr Lys His
                 290                 295                 300

 Leu Lys Asp Leu Leu Ser Lys Leu Leu Asn Ser Gly Tyr Phe Glu
                 305                 310                 315

 Ser Ile Pro Val Pro Lys Asn Ala Lys Glu Lys Glu Val Pro Leu
                 320                 325                 330

 Glu Glu Glu Met Leu Ile Gln Ser Glu Lys Lys Thr Gln Leu Ser
                 335                 340                 345

 Lys Thr Glu Ser Val Lys Glu Ser Glu Ser Leu Met Glu Phe Ala
                 350                 355                 360

 Gln Pro Glu Ile Gln Pro Gln Glu Phe Leu Asn Arg Arg Tyr Met
                 365                 370                 375

 Thr Glu Val Asp Tyr Ser Asn Lys Gln Gly Glu Glu Gln Pro Trp
                 380                 385                 390

 Glu Ala Asp Tyr Ala Arg Lys Pro Asn Leu Pro Lys Arg Trp Asp
                 395                 400                 405

 Met Leu Thr Glu Pro Asp Gly Gln Glu Lys Lys Gln Glu Ser Phe
                 410                 415                 420

 Lys Ser Trp Glu Ala Ser Gly Lys His Gln Glu Val Ser Lys Pro
                 425                 430                 435

 Ala Val Ser Leu Glu Gln Arg Lys Gln Asp Thr Ser Lys Leu Arg
                 440                 445                 450

 Ser Thr Leu Pro Glu Glu Gln Lys Lys Gln Glu Ile Ser Lys Ser
                 455                 460                 465

 Lys Pro Ser Pro Ser Gln Trp Lys Gln Asp Thr Pro Lys Ser Lys
                 470                 475                 480

 Ala Gly Tyr Val Gln Glu Glu Gln Lys Lys Gln Glu Thr Pro Lys
                 485                 490                 495

 Leu Trp Pro Val Gln Leu Gln Lys Glu Gln Asp Pro Lys Lys Gln
                 500                 505                 510

 Thr Pro Lys Ser Trp Thr Pro Ser Met Gln Ser Glu Gln Asn Thr
                 515                 520                 525

 Thr Lys Ser Trp Thr Thr Pro Met Cys Glu Glu Gln Asp Ser Lys
                 530                 535                 540

 Gln Pro Glu Thr Pro Lys Ser Trp Glu Asn Asn Val Glu Ser Gln
                 545                 550                 555

 Lys His Ser Leu Thr Ser Gln Ser Gln Ile Ser Pro Lys Ser Trp
                 560                 565                 570

 Gly Val Ala Thr Ala Ser Leu Ile Pro Asn Asp Gln Leu Leu Pro
                 575                 580                 585

 Arg Lys Leu Asn Thr Glu Pro Lys Asp Val Pro Lys Pro Val His
                 590                 595                 600

 Gln Pro Val Gly Ser Ser Ser Thr Leu Pro Lys Asp Pro Val Leu
                 605                 610                 615

 Arg Lys Glu Lys Leu Gln Asp Leu Met Thr Gln Ile Gln Gly Thr
                 620                 625                 630

 Cys Asn Phe Met Gln Glu Ser Val Leu Asp Phe Asp Lys Pro Ser
                 635                 640                 645

 Ser Ala Ile Pro Thr Ser Gln Pro Pro Ser Ala Thr Pro Gly Ser
                 650                 655                 660

 Pro Val Ala Ser Lys Glu Gln Asn Leu Ser Ser Gln Ser Asp Phe
                 665                 670                 675

 Leu Gln Glu Pro Leu Gln Ala Thr Ser Ser Pro Val Thr Cys Ser
                 680                 685                 690

 Ser Asn Ala Cys Leu Val Thr Thr Asp Gln Ala Ser Ser Gly Ser
                 695                 700                 705

 Glu Thr Glu Phe Met Thr Ser Glu Thr Pro Glu Val Phe Asn Val
                 710                 715                 720

 Asn Ala Pro Leu Pro Pro Arg Lys Glu Gln Glu Ile Lys Glu Ser
                 725                 730                 735

 Pro Tyr Ser Pro Gly Tyr Asn Gln Ser Phe Thr Thr Ala Ser Thr
                 740                 745                 750

 Gln Thr Pro Pro Gln Cys Gln Leu Pro Ser Ile His Val Glu Gln
                 755                 760                 765

 Thr Val His Ser Gln Glu Thr Ala Asn Tyr His Pro Asp Gly Thr
                 770                 775                 780

 Ile Gln Val Ser Asn Gly Ser Leu Ala Phe Tyr Pro Ala Gln Thr
                 785                 790                 795

 Asn Val Phe Pro Arg Pro Thr Gln Pro Phe Val Asn Ser Arg Gly
                 800                 805                 810

 Ser Val Arg Gly Cys Thr Arg Gly Gly Arg Leu Ile Thr Asn Ser
                 815                 820                 825

 Tyr Arg Ser Pro Gly Gly Tyr Lys Gly Phe Asp Thr Tyr Arg Gly
                 830                 835                 840

 Leu Pro Ser Ile Ser Asn Gly Asn Tyr Ser Gln Leu Gln Phe Gln
                 845                 850                 855

 Ala Arg Glu Tyr Ser Gly Ala Pro Tyr Ser Gln Arg Asp Asn Phe
                 860                 865                 870

 Gln Gln Cys Tyr Lys Arg Gly Gly Thr Ser Gly Gly Pro Arg Ala
                 875                 880                 885

 Asn Ser Arg Ala Gly Trp Ser Asp Ser Ser Gln Val Ser Ser Pro
                 890                 895                 900

 Glu Arg Asp Asn Glu Thr Phe Asn Ser Gly Asp Ser Gly Gln Gly
                 905                 910                 915

 Asp Ser Arg Ser Met Thr Pro Val Asp Val Pro Val Thr Asn Pro
                 920                 925                 930

 Ala Ala Thr Ile Leu Pro Val His Val Tyr Pro Leu Pro Gln Gln
                 935                 940                 945

 Met Arg Val Ala Phe Ser Ala Ala Arg Thr Ser Asn Leu Ala Pro
                 950                 955                 960

 Gly Thr Leu Asp Gln Pro Ile Val Phe Asp Leu Leu Leu Asn Asn
                 965                 970                 975

 Leu Gly Glu Thr Phe Asp Leu Gln Leu Gly Arg Phe Asn Cys Pro
                 980                 985                 990

 Val Asn Gly Thr Tyr Val Phe Ile Phe His Met Leu Lys Leu Ala
                 995                1000                1005

 Val Asn Val Pro Leu Tyr Val Asn Leu Met Lys Asn Glu Glu Val
                1010                1015                1020

 Leu Val Ser Ala Tyr Ala Asn Asp Gly Ala Pro Asp His Glu Thr
                1025                1030                1035

 Ala Ser Asn His Ala Ile Leu Gln Leu Phe Gln Gly Asp Gln Ile
                1040                1045                1050

 Trp Leu Arg Leu His Arg Gly Ala Ile Tyr Gly Ser Ser Trp Lys
                1055                1060                1065

 Tyr Ser Thr Phe Ser Gly Tyr Leu Leu Tyr Gln Asp
                1070                1075

<210> 3223
<211> 1680
<212> DNA
<213> Homo sapien

<400> 3223
 gcccgctgtt gcgtgctgcc agcgggaact gtgtaggggt agattttcgc 50

 tgcagtgttc cccgagcctg ttagacgcag cgcgccggga gactgagaga 100

 ggaaaggata gaggaagtgc tgccctaggc tgcatgagtc gaagcaagcg 150

 tgtttccttc ccgccaggca agtgccctta gaaaccgggc cccgccccct 200

 tcctggcctg cattcccatc ccctctcccg gggcggaggt gaggacctct 250

 ttggttcctt tggttctgtc agtgagcccc ttccttggcc atgaagctcg 300

 tgaggaagaa catcgagaag gacaatgcgg gccaggtgac cctggtcccc 350

 gaggagcctg aggacatgtg gcacacttac aacctcgtgc aggtgggcga 400

 cagcctgcgc gcctccacca tccgcaaggt acagacagag tcctccacgg 450

 gcagcgtggg cagcaaccgg gtccgcacta ccctcactct ctgcgtggag 500

 gccatcgact tcgactctca agcctgccag ctgcgggtta aggggaccaa 550

 catccaagag aatgagtatg tcaagatggg ggcttaccac accatcgagc 600

 tggagcccaa ccgccagttc accctggcca agaagcagtg ggatagtgtg 650

 gtactggagc gcatcgagca ggcctgtgac ccagcctgga gcgctgatgt 700

 ggcggctgtg gtcatgcagg aaggcctcgc ccatatctgc ttagtcactc 750

 ccagcatgac cctcactcgg gccaaggtgg aggtgaacat ccctaggaaa 800

 aggaaaggca attgctctca gcatgaccgg gccttggagc ggttctatga 850

 acaggtggtc caggctatcc agcgccacat acactttgat gttgtaaagt 900

 gcatcctggt ggccagccca ggatttgtga gggagcagtt ctgcgactac 950

 atgtttcaac aagcagtgaa gaccgacaac aaactgctcc tggaaaaccg 1000

 gtccaaattt cttcaggtac atgcctcctc cggacacaag tactccctga 1050

 aagaggccct ttgtgaccct actgtggcta gccgcctttc agacactaaa 1100

 gctgctgggg aagtcaaagc cttggatgac ttctataaaa tgttacagca 1150

 tgaaccggat cgagctttct atggactcaa gcaggtggag aaggccaatg 1200

 aagccatggc aattgacaca ttgctcatca gcgatgagct cttcaggcat 1250

 caggatgtag ccacacggag ccggtatgtg aggctggtgg acagtgtgaa 1300

 agagaatgca ggcaccgtta ggatattctc tagtcttcac gtttctgggg 1350

 aacagctcag ccagttgact ggggtagctg ccattctccg cttccctgtt 1400

 cccgaacttt ctgaccaaga gggtgattcc agttctgaag aggattaatg 1450

 attgaaactt aaaattgaga caatcttgtg tttcctaaac tgttacagta 1500

 catttctcag catccttgtg acagaaagct gcaagaaggg cactttttga 1550

 ttcatacagg gatttcttat gtctttggct acactagata ttttgtgatt 1600

 ggcaagacat gtatttaaac ataaactaaa aggaaataaa aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1680

<210> 3224
<211> 385
<212> PRT
<213> Homo sapien

<400> 3224
 Met Lys Leu Val Arg Lys Asn Ile Glu Lys Asp Asn Ala Gly Gln
   1               5                  10                  15

 Val Thr Leu Val Pro Glu Glu Pro Glu Asp Met Trp His Thr Tyr
                  20                  25                  30

 Asn Leu Val Gln Val Gly Asp Ser Leu Arg Ala Ser Thr Ile Arg
                  35                  40                  45

 Lys Val Gln Thr Glu Ser Ser Thr Gly Ser Val Gly Ser Asn Arg
                  50                  55                  60

 Val Arg Thr Thr Leu Thr Leu Cys Val Glu Ala Ile Asp Phe Asp
                  65                  70                  75

 Ser Gln Ala Cys Gln Leu Arg Val Lys Gly Thr Asn Ile Gln Glu
                  80                  85                  90

 Asn Glu Tyr Val Lys Met Gly Ala Tyr His Thr Ile Glu Leu Glu
                  95                 100                 105

 Pro Asn Arg Gln Phe Thr Leu Ala Lys Lys Gln Trp Asp Ser Val
                 110                 115                 120

 Val Leu Glu Arg Ile Glu Gln Ala Cys Asp Pro Ala Trp Ser Ala
                 125                 130                 135

 Asp Val Ala Ala Val Val Met Gln Glu Gly Leu Ala His Ile Cys
                 140                 145                 150

 Leu Val Thr Pro Ser Met Thr Leu Thr Arg Ala Lys Val Glu Val
                 155                 160                 165

 Asn Ile Pro Arg Lys Arg Lys Gly Asn Cys Ser Gln His Asp Arg
                 170                 175                 180

 Ala Leu Glu Arg Phe Tyr Glu Gln Val Val Gln Ala Ile Gln Arg
                 185                 190                 195

 His Ile His Phe Asp Val Val Lys Cys Ile Leu Val Ala Ser Pro
                 200                 205                 210

 Gly Phe Val Arg Glu Gln Phe Cys Asp Tyr Met Phe Gln Gln Ala
                 215                 220                 225

 Val Lys Thr Asp Asn Lys Leu Leu Leu Glu Asn Arg Ser Lys Phe
                 230                 235                 240

 Leu Gln Val His Ala Ser Ser Gly His Lys Tyr Ser Leu Lys Glu
                 245                 250                 255

 Ala Leu Cys Asp Pro Thr Val Ala Ser Arg Leu Ser Asp Thr Lys
                 260                 265                 270

 Ala Ala Gly Glu Val Lys Ala Leu Asp Asp Phe Tyr Lys Met Leu
                 275                 280                 285

 Gln His Glu Pro Asp Arg Ala Phe Tyr Gly Leu Lys Gln Val Glu
                 290                 295                 300

 Lys Ala Asn Glu Ala Met Ala Ile Asp Thr Leu Leu Ile Ser Asp
                 305                 310                 315

 Glu Leu Phe Arg His Gln Asp Val Ala Thr Arg Ser Arg Tyr Val
                 320                 325                 330

 Arg Leu Val Asp Ser Val Lys Glu Asn Ala Gly Thr Val Arg Ile
                 335                 340                 345

 Phe Ser Ser Leu His Val Ser Gly Glu Gln Leu Ser Gln Leu Thr
                 350                 355                 360

 Gly Val Ala Ala Ile Leu Arg Phe Pro Val Pro Glu Leu Ser Asp
                 365                 370                 375

 Gln Glu Gly Asp Ser Ser Ser Glu Glu Asp
                 380                 385

<210> 3225
<211> 3334
<212> DNA
<213> Homo sapien

<400> 3225
 gcacgagccc cgggctgccg gcgcgggcgc cgcggcacgt ccacaggctg 50

 ggtcgcgagg tggcgatcgc tgagaggcag gagggccgag gcgggcctgg 100

 gaggcggccc ggaggtgggg cgccgctggg gccggcccgc acgggcttca 150

 tctgagggcg cacggcccgc gaccgagcgt gcggactggc ctcccaagcg 200

 tggggcgaca agctgccgga gctgcaatgg gccgcggctg gggattcttg 250

 tttggcctcc tgggcgccgt gtggctgctc agctcgggcc acggagagga 300

 gcagcccccg gagacagcgg cacagaggtg cttctgccag gttagtggtt 350

 acttggatga ttgtacctgt gatgttgaaa ccattgatag atttaataac 400

 tacaggcttt tcccaagact acaaaaactt cttgaaagtg actactttag 450

 gtattacaag gtaaacctga agaggccgtg tcctttctgg aatgacatca 500

 gccagtgtgg aagaagggac tgtgctgtca aaccatgtca atctgatgaa 550

 gttcctgatg gaattaaatc tgcgagctac aagtattctg aagaagccaa 600

 taatctcatt gaagaatgtg aacaagctga acgacttgga gcagtggatg 650

 aatctctgag tgaggaaaca cagaaggctg ttcttcagtg gaccaagcat 700

 gatgattctt cagataactt ctgtgaagct gatgacattc agtcccctga 750

 agctgaatat gtagatttgc ttcttaatcc tgagcgctac actggttaca 800

 agggaccaga tgcttggaaa atatggaatg tcatctacga agaaaactgt 850

 tttaagccac agacaattaa aagaccttta aatcctttgg cttctggtca 900

 agggacaagt gaagagaaca ctttttacag ttggctagaa ggtctctgtg 950

 tagaaaaaag agcattctac agacttatat ctggcctaca tgcaagcatt 1000

 aatgtgcatt tgagtgcaag atatctttta caagagacct ggttagaaaa 1050

 gaaatgggga cacaacatta cagaatttca acagcgattt gatggaattt 1100

 tgactgaagg agaaggtcca agaaggctta agaacttgta ttttctctac 1150

 ttaatagaac taagggcttt atccaaagtg ttaccattct tcgagcgccc 1200

 agattttcaa ctctttactg gaaataaaat tcaggatgag gaaaacaaaa 1250

 tgttacttct ggaaatactt catgaaatca agtcatttcc tttgcatttt 1300

 gatgagaatt cattttttgc tggggataaa aaagaagcac acaaactaaa 1350

 ggaggacttt cgactgcatt ttagaaatat ttcaagaatt atggattgtg 1400

 ttggttgttt taaatgtcgt ctgtggggaa agcttcagac tcagggtttg 1450

 ggcactgctc tgaagatctt attttctgag aaattgatag caaatatgcc 1500

 agaaagtgga cctagttatg aattccatct aaccagacaa gaaatagtat 1550

 cattattcaa cgcatttgga agaatttcta caagtgtgaa agaattagaa 1600

 aacttcagga acttgttaca gaatattcat taaagaaaac aagctgatat 1650

 gtgcctgttt ctggacaatg gaggcgaaag agtggaattt cattcaaagg 1700

 cataatagca atgacagtct taagccaaac attttatata aagttgcttt 1750

 tgtaaaggag aattatattg ttttaagtaa acacattttt aaaaattgtg 1800

 ttaagtctat gtataatact actgtgagta aaagtaatac tttaataatg 1850

 tggtacaaat tttaaagttt aatattgaat aaaaggagga ttatcaaatt 1900

 catatatgat aaaagtgaat gttctaagtc tctcaaacta gcgttttatg 1950

 taataatatg taatataaat aaaactatgg taaatgtgac aagcatttaa 2000

 taggaaaatg ctaaggaggc ctcataaatg acccataatt accaacgtag 2050

 aatttttcag tacatttagg gttgctggat ttagcaaata aaaataaaga 2100

 ttgcccagtt agatttgaat ttcagataaa caattagttt tttaatattt 2150

 tacatggaat atttggaaaa tacttatact aaaaaattat ttgtttgaaa 2200

 ttcacattta actgggagtc ttgtatttta tctggcaatc ctaaaataca 2250

 ttggtatgaa acaaatcact tttagaagta tattgctatt ttgattgggt 2300

 tgtttttgtg tgtagaaacg tacaataaca actcaaaggc acaggagatt 2350

 tctaaacatt gtgaaaagtt gaatagatta tatatttatt ctcataatac 2400

 tttcactaat actaaataaa atttggggaa cactttttat ttttatataa 2450

 tttccaattt acagaaaagt ttcaaaaata gtacaaagag ctctcttacc 2500

 cagattcact aattgttcat acgtgcttta tctttcatgc tttctctgta 2550

 cacacacaca cacacacaaa tttttcctca atcatttgaa agtcagttat 2600

 aggcatcatg ccccttaaac cctaaatact tcagtgtgta atactgaata 2650

 attactaaaa atgattttct cagaaaaaaa aactcccaca attctggaac 2700

 tataatactg taagccttag aataaataat actttcaagt tccaatctaa 2750

 agttcttttt gagttttgtt gcccgtttta tgcttgatgt gtatagtaat 2800

 agggtaggct atttatttta ttaaaatttt ttttagagac aaggttttgc 2850

 tgtgttgccc aagctggaac ttgaacgact gggctgaagt gatcttccca 2900

 cctcagcctc ccaagtagct gggaatacag gtgtctgcca ccatacccag 2950

 tttcattttt gttttttata cccgaagttc atttcctttg tctccctaaa 3000

 actgaactgt aattttggga ggttttcatt agtggaagct cttcatttat 3050

 aaagctattt gaaggggttt aggaatttat atcacatggt aattgtagag 3100

 aaaaagaagc tatatacctc aaaatcgtgc cctctttaca tatgtcttat 3150

 caggtataac atgttgaaat gtcacattag tagtaaagtg gggtttattt 3200

 atatagtggt taagaaatgt cagtttacac tgctgtatac ttcttcttct 3250

 gtgtccctaa ggcctggtac agtgccaagc acatacttgg tatccaataa 3300

 atatttgttg gatgaaaaaa aaaaaaaaaa aaaa 3334

<210> 3226
<211> 468
<212> PRT
<213> Homo sapien

<400> 3226
 Met Gly Arg Gly Trp Gly Phe Leu Phe Gly Leu Leu Gly Ala Val
   1               5                  10                  15

 Trp Leu Leu Ser Ser Gly His Gly Glu Glu Gln Pro Pro Glu Thr
                  20                  25                  30

 Ala Ala Gln Arg Cys Phe Cys Gln Val Ser Gly Tyr Leu Asp Asp
                  35                  40                  45

 Cys Thr Cys Asp Val Glu Thr Ile Asp Arg Phe Asn Asn Tyr Arg
                  50                  55                  60

 Leu Phe Pro Arg Leu Gln Lys Leu Leu Glu Ser Asp Tyr Phe Arg
                  65                  70                  75

 Tyr Tyr Lys Val Asn Leu Lys Arg Pro Cys Pro Phe Trp Asn Asp
                  80                  85                  90

 Ile Ser Gln Cys Gly Arg Arg Asp Cys Ala Val Lys Pro Cys Gln
                  95                 100                 105

 Ser Asp Glu Val Pro Asp Gly Ile Lys Ser Ala Ser Tyr Lys Tyr
                 110                 115                 120

 Ser Glu Glu Ala Asn Asn Leu Ile Glu Glu Cys Glu Gln Ala Glu
                 125                 130                 135

 Arg Leu Gly Ala Val Asp Glu Ser Leu Ser Glu Glu Thr Gln Lys
                 140                 145                 150

 Ala Val Leu Gln Trp Thr Lys His Asp Asp Ser Ser Asp Asn Phe
                 155                 160                 165

 Cys Glu Ala Asp Asp Ile Gln Ser Pro Glu Ala Glu Tyr Val Asp
                 170                 175                 180

 Leu Leu Leu Asn Pro Glu Arg Tyr Thr Gly Tyr Lys Gly Pro Asp
                 185                 190                 195

 Ala Trp Lys Ile Trp Asn Val Ile Tyr Glu Glu Asn Cys Phe Lys
                 200                 205                 210

 Pro Gln Thr Ile Lys Arg Pro Leu Asn Pro Leu Ala Ser Gly Gln
                 215                 220                 225

 Gly Thr Ser Glu Glu Asn Thr Phe Tyr Ser Trp Leu Glu Gly Leu
                 230                 235                 240

 Cys Val Glu Lys Arg Ala Phe Tyr Arg Leu Ile Ser Gly Leu His
                 245                 250                 255

 Ala Ser Ile Asn Val His Leu Ser Ala Arg Tyr Leu Leu Gln Glu
                 260                 265                 270

 Thr Trp Leu Glu Lys Lys Trp Gly His Asn Ile Thr Glu Phe Gln
                 275                 280                 285

 Gln Arg Phe Asp Gly Ile Leu Thr Glu Gly Glu Gly Pro Arg Arg
                 290                 295                 300

 Leu Lys Asn Leu Tyr Phe Leu Tyr Leu Ile Glu Leu Arg Ala Leu
                 305                 310                 315

 Ser Lys Val Leu Pro Phe Phe Glu Arg Pro Asp Phe Gln Leu Phe
                 320                 325                 330

 Thr Gly Asn Lys Ile Gln Asp Glu Glu Asn Lys Met Leu Leu Leu
                 335                 340                 345

 Glu Ile Leu His Glu Ile Lys Ser Phe Pro Leu His Phe Asp Glu
                 350                 355                 360

 Asn Ser Phe Phe Ala Gly Asp Lys Lys Glu Ala His Lys Leu Lys
                 365                 370                 375

 Glu Asp Phe Arg Leu His Phe Arg Asn Ile Ser Arg Ile Met Asp
                 380                 385                 390

 Cys Val Gly Cys Phe Lys Cys Arg Leu Trp Gly Lys Leu Gln Thr
                 395                 400                 405

 Gln Gly Leu Gly Thr Ala Leu Lys Ile Leu Phe Ser Glu Lys Leu
                 410                 415                 420

 Ile Ala Asn Met Pro Glu Ser Gly Pro Ser Tyr Glu Phe His Leu
                 425                 430                 435

 Thr Arg Gln Glu Ile Val Ser Leu Phe Asn Ala Phe Gly Arg Ile
                 440                 445                 450

 Ser Thr Ser Val Lys Glu Leu Glu Asn Phe Arg Asn Leu Leu Gln
                 455                 460                 465

 Asn Ile His


<210> 3227
<211> 1372
<212> DNA
<213> Homo sapien

<400> 3227
 gcacgagggc gcttttgtct ccggtgagtt ttgtggcggg aagcttctgc 50

 gctggtgctt agtaaccgac tttcctccgg actcctgcac gacctgctcc 100

 tacagccggc gatccactcc cggctgttcc cccggagggt ccagaggcct 150

 ttcagaagga gaaggcagct ctgtttctct gcagaggagt agggtccttt 200

 cagccatgaa gcatgtgttg aacctctacc tgttaggtgt ggtactgacc 250

 ctactctcca tcttcgttag agtgatggag tccctagaag gcttactaga 300

 gagcccatcg cctgggacct cctggaccac cagaagccaa ctagccaaca 350

 cagagcccac caagggcctt ccagaccatc catccagaag catgtgataa 400

 gacctccttc catactggcc atattttgga acactgacct agacatgtcc 450

 agatgggagt cccattccta gcagacaagc tgagcaccgt tgtaaccaga 500

 gaactattac taggccttga agaacctgtc taactggatg ctcattgcct 550

 gggcaaggcc tgtttaggcc ggttgcggtg gctcatgcct gtaatcctag 600

 cactttggga ggctgaggtg ggtggatcac ctgaggtcag gagttcgaga 650

 ccagcctcgc caacatggcg aaaccccatc tctactaaaa atacaaaagt 700

 tagctgggtg tggtggcaga ggcctgtaat cccagttcct tgggaggctg 750

 aggcgggaga attgcttgaa cccggggacg gaggttgcag tgaaccgaga 800

 tcgcactgct gtacccagcc tgggccacag tgcaagactc catctcaaaa 850

 aaaaaaagaa aagaaaaagc ctgtttaatg cacaggtgtg agtggattgc 900

 ttatggctat gagataggtt gatctcgccc ttaccccggg gtctggtgta 950

 tgctgtgctt tcctcagcag tatggctctg acatctctta gatgtcccaa 1000

 cttcagctgt tgggagatgg tgatattttc aaccctactt cctaaacatc 1050

 tgtctggggt tcctttagtc ttgaatgtct tatgctcaat tatttggtgt 1100

 tgagcctctc ttccacaaga gctcctccat gtttggatag cagttgaaga 1150

 ggttgtgtgg gtgggctgtt gggagtgagg atggagtgtt cagtgcccat 1200

 ttctcatttt acattttaaa gtcgttcctc caacatagtg tgtattggtc 1250

 tgaagggggt ggtgggatgc caaagcctgc tcaagttatg gacattgtgg 1300

 ccaccatgtg gcttaaatga ttttttctaa ctaataaagt ggaatatata 1350

 tttcaaaaaa aaaaaaaaaa aa 1372

<210> 3228
<211> 63
<212> PRT
<213> Homo sapien

<400> 3228
 Met Lys His Val Leu Asn Leu Tyr Leu Leu Gly Val Val Leu Thr
   1               5                  10                  15

 Leu Leu Ser Ile Phe Val Arg Val Met Glu Ser Leu Glu Gly Leu
                  20                  25                  30

 Leu Glu Ser Pro Ser Pro Gly Thr Ser Trp Thr Thr Arg Ser Gln
                  35                  40                  45

 Leu Ala Asn Thr Glu Pro Thr Lys Gly Leu Pro Asp His Pro Ser
                  50                  55                  60

 Arg Ser Met


<210> 3229
<211> 1240
<212> DNA
<213> Homo sapien

<400> 3229
 tgcgcgtgcg cagggataag agagcggtct ggacagcgcg tggccggcgc 50

 cgctgtgggg acagcatgag cggcggttgg atggcgcagg ttggagcgtg 100

 gcgaacaggg gctctgggcc tggcgctgct gctgctgctc ggcctcggac 150

 taggcctgga ggccgccgcg agcccgcttt ccaccccgac ctctgcccag 200

 gccgcaggcc ccagctcagg ctcgtgccca cccaccaagt tccagtgccg 250

 caccagtggc ttatgcgtgc ccctcacctg gcgctgcgac agggacttgg 300

 actgcagcga tggcagcgat gaggaggagt gcaggattga gccatgtacc 350

 cagaaagggc aatgcccacc gccccctggc ctcccctgcc cctgcaccgg 400

 cgtcagtgac tgctctgggg gaactgacaa gaaactgcgc aactgcagcc 450

 gcctggcctg cctagcaggc gagctccgtt gcacgctgag cgatgactgc 500

 attccactca cgtggcgctg cgacggccac ccagactgtc ccgactccag 550

 cgacgagctc ggctgtggaa ccaatgagat cctcccggaa ggggatgcca 600

 caaccatggg gccccctgtg accctggaga gtgtcacctc tctcaggaat 650

 gccacaacca tggggccccc tgtgaccctg gagagtgtcc cctctgtcgg 700

 gaatgccaca tcctcctctg ccggagacca gtctggaagc ccaactgcct 750

 atggggttat tgcagctgct gcggtgctca gtgcaagcct ggtcaccgcc 800

 accctcctcc ttttgtcctg gctccgagcc caggagcgcc tccgcccact 850

 ggggttactg gtggccatga aggagtccct gctgctgtca gaacagaaga 900

 cctcgctgcc ctgaggacaa gcacttgcca ccaccgtcac tcagccctgg 950

 gcgtagccgg acaggaggag agcagtgatg cggatgggta cccgggcaca 1000

 ccagccctca gagacctgag ctcttctggc cacgtggaac ctcgaacccg 1050

 agctcctgca gaagtggccc tggagattga gggtccctgg acactcccta 1100

 tggagatccg gggagctagg atggggaacc tgccacagcc agaactgagg 1150

 ggctggcccc aggcagctcc cagggggtag aacggccctg tgcttaagac 1200

 actcctgctg ccccgtctga gggtggcgat taaagttgct 1240

<210> 3230
<211> 282
<212> PRT
<213> Homo sapien

<400> 3230
 Met Ser Gly Gly Trp Met Ala Gln Val Gly Ala Trp Arg Thr Gly
   1               5                  10                  15

 Ala Leu Gly Leu Ala Leu Leu Leu Leu Leu Gly Leu Gly Leu Gly
                  20                  25                  30

 Leu Glu Ala Ala Ala Ser Pro Leu Ser Thr Pro Thr Ser Ala Gln
                  35                  40                  45

 Ala Ala Gly Pro Ser Ser Gly Ser Cys Pro Pro Thr Lys Phe Gln
                  50                  55                  60

 Cys Arg Thr Ser Gly Leu Cys Val Pro Leu Thr Trp Arg Cys Asp
                  65                  70                  75

 Arg Asp Leu Asp Cys Ser Asp Gly Ser Asp Glu Glu Glu Cys Arg
                  80                  85                  90

 Ile Glu Pro Cys Thr Gln Lys Gly Gln Cys Pro Pro Pro Pro Gly
                  95                 100                 105

 Leu Pro Cys Pro Cys Thr Gly Val Ser Asp Cys Ser Gly Gly Thr
                 110                 115                 120

 Asp Lys Lys Leu Arg Asn Cys Ser Arg Leu Ala Cys Leu Ala Gly
                 125                 130                 135

 Glu Leu Arg Cys Thr Leu Ser Asp Asp Cys Ile Pro Leu Thr Trp
                 140                 145                 150

 Arg Cys Asp Gly His Pro Asp Cys Pro Asp Ser Ser Asp Glu Leu
                 155                 160                 165

 Gly Cys Gly Thr Asn Glu Ile Leu Pro Glu Gly Asp Ala Thr Thr
                 170                 175                 180

 Met Gly Pro Pro Val Thr Leu Glu Ser Val Thr Ser Leu Arg Asn
                 185                 190                 195

 Ala Thr Thr Met Gly Pro Pro Val Thr Leu Glu Ser Val Pro Ser
                 200                 205                 210

 Val Gly Asn Ala Thr Ser Ser Ser Ala Gly Asp Gln Ser Gly Ser
                 215                 220                 225

 Pro Thr Ala Tyr Gly Val Ile Ala Ala Ala Ala Val Leu Ser Ala
                 230                 235                 240

 Ser Leu Val Thr Ala Thr Leu Leu Leu Leu Ser Trp Leu Arg Ala
                 245                 250                 255

 Gln Glu Arg Leu Arg Pro Leu Gly Leu Leu Val Ala Met Lys Glu
                 260                 265                 270

 Ser Leu Leu Leu Ser Glu Gln Lys Thr Ser Leu Pro
                 275                 280

<210> 3231
<211> 2644
<212> DNA
<213> Homo sapien

<400> 3231
 ggcacgaggg gccgacgcga gcgccgcgct tcgcttcagc tgctagctgg 50

 cccaagggag gcgaccgcgg agggtggcga ggggcggcca ggacccgcag 100

 ccccggggcc gggccggtcc ggaccgccag ggagggcagg tcagtgggca 150

 gatcgcgtcc gcgggattca atctctgccc gctctgataa cagtcctttt 200

 ccctggcgct cacttcgtgc ctggcacccg gctgggcgcc tcaagaccgt 250

 tgtctcttcg atcgcttctt tggacttggc gaccatttca gagatgtctt 300

 ccagaagtac caaagattta attaaaagta agtggggatc gaagcctagt 350

 aactccaaat ccgaaactac attagaaaaa ttaaagggag aaattgcaca 400

 cttaaagaca tcagtggatg aaatcacaag tgggaaagga aagctgactg 450

 ataaagagag acacagactt ttggagaaaa ttcgagtcct tgaggctgag 500

 aaggagaaga atgcttatca actcacagag aaggacaaag aaatacagcg 550

 actgagagac caactgaagg ccagatatag tactaccgca ttgcttgaac 600

 agctggaaga gacaacgaga gaaggagaaa ggagggagca ggtgttgaaa 650

 gccttatctg aagagaaaga cgtattgaaa caacagttgt ctgctgcaac 700

 ctcacgaatt gctgaacttg aaagcaaaac caatacactc cgtttatcac 750

 agactgtggc tccaaactgc ttcaactcat caataaataa tattcatgaa 800

 atggaaatac agctgaaaga tgctctggag aaaaatcagc agtggctcgt 850

 gtatgatcag cagcgggaag tctatgtaaa aggactttta gcaaagatct 900

 ttgagttgga aaagaaaacg gaaacagctg ctcattcact cccacagcag 950

 acaaaaaagc ctgaatcaga aggttatctt caagaagaga agcagaaatg 1000

 ttacaacgat ctcttggcaa gtgcaaaaaa agatcttgag gttgaacgac 1050

 aaaccataac tcagctgagt tttgaactga gtgaatttcg aagaaaatat 1100

 gaagaaaccc aaaaagaagt tcacaattta aatcagctgt tgtattcaca 1150

 aagaagggca gatgtgcaac atctggaaga tgataggcat aaaacagaga 1200

 agatacaaaa actcagggaa gagaatgata ttgctagggg aaaacttgaa 1250

 gaagagaaga agagatccga agagctctta tctcaggtcc agtttcttta 1300

 cacatctctg ctaaagcagc aagaagaaca aacaagggta gctctgttgg 1350

 aacaacagat gcaggcatgt actttagact ttgaaaatga aaaactcgac 1400

 cgtcaacatg tgcagcatca attgcttgta attcttaagg agctccgaaa 1450

 agcaagaaat caaataacac agttggaatc cttgaaacag cttcatgagt 1500

 ttgccatcac agagccatta gtcactttcc aaggagagac tgaaaacaga 1550

 gaaaaagttg ccgcctcacc aaaaagtccc actgctgcac tcaatgaaag 1600

 cctggtggaa tgtcccaagt gcaatataca gtatccagcc actgagcatc 1650

 gcgatctgct tgtccatgtg gaatactgtt caaagtagca aaataagtat 1700

 ttgttttgat attaaaagat tcaatactgt attttctgtt agcttgtggg 1750

 cattttgaat tatatatttc acattttgca taaaactgcc tatctacctt 1800

 tgacactcca gcatgctagt gaatcatgta tcttttaggc tgctgtgcat 1850

 ttctcttggc agtgatacct ccctgacatg gttcatcatc aggctgcaat 1900

 gacagaatgt ggtgagcagc gtctactgag actactaaca ttttgcactg 1950

 tcaaaatact tggtgaggaa aagatagctc aggttattgc taatgggtta 2000

 atgcaccagc aagcaaaata ttttatgttt tgggggtttg aaaaatcaaa 2050

 gataattaac caaggatctt aactgtgttc gcatttttta tccaagcact 2100

 tagaaaacct acaatcctaa ttttgatgtc cattgttaag aggtggtgat 2150

 agatactatt ttttttttca tattgtatag cggttattag aaaagttggg 2200

 gattttcttg atctttattg ctgcttacca ttgaaactta acccagctgt 2250

 gttccccaac tctgttctgc gcacgaaaca gtatctgttt gaggcataat 2300

 cttaagtggc cacacacaat gttttctctt atgttatctg gcagtaactg 2350

 taacttgaat tacattagca cattctgctt agctaaaatt gttaaaataa 2400

 actttaataa acccatgtag ccctctcatt tgattgacag tattttagtt 2450

 atttttggca ttcttaaagc tgggcaatgt aatgatcaga tctttgtttg 2500

 tctgaacagg tatttttata catgcttttt gtaaaccaaa aacttttaaa 2550

 tttcttcagg ttttctaaca tgcttaccac tgggctactg taaatgagaa 2600

 aagaataaaa ttatttaatg ttttaaaaaa aaaaaaaaaa aaaa 2644

<210> 3232
<211> 464
<212> PRT
<213> Homo sapien

<400> 3232
 Met Ser Ser Arg Ser Thr Lys Asp Leu Ile Lys Ser Lys Trp Gly
   1               5                  10                  15

 Ser Lys Pro Ser Asn Ser Lys Ser Glu Thr Thr Leu Glu Lys Leu
                  20                  25                  30

 Lys Gly Glu Ile Ala His Leu Lys Thr Ser Val Asp Glu Ile Thr
                  35                  40                  45

 Ser Gly Lys Gly Lys Leu Thr Asp Lys Glu Arg His Arg Leu Leu
                  50                  55                  60

 Glu Lys Ile Arg Val Leu Glu Ala Glu Lys Glu Lys Asn Ala Tyr
                  65                  70                  75

 Gln Leu Thr Glu Lys Asp Lys Glu Ile Gln Arg Leu Arg Asp Gln
                  80                  85                  90

 Leu Lys Ala Arg Tyr Ser Thr Thr Ala Leu Leu Glu Gln Leu Glu
                  95                 100                 105

 Glu Thr Thr Arg Glu Gly Glu Arg Arg Glu Gln Val Leu Lys Ala
                 110                 115                 120

 Leu Ser Glu Glu Lys Asp Val Leu Lys Gln Gln Leu Ser Ala Ala
                 125                 130                 135

 Thr Ser Arg Ile Ala Glu Leu Glu Ser Lys Thr Asn Thr Leu Arg
                 140                 145                 150

 Leu Ser Gln Thr Val Ala Pro Asn Cys Phe Asn Ser Ser Ile Asn
                 155                 160                 165

 Asn Ile His Glu Met Glu Ile Gln Leu Lys Asp Ala Leu Glu Lys
                 170                 175                 180

 Asn Gln Gln Trp Leu Val Tyr Asp Gln Gln Arg Glu Val Tyr Val
                 185                 190                 195

 Lys Gly Leu Leu Ala Lys Ile Phe Glu Leu Glu Lys Lys Thr Glu
                 200                 205                 210

 Thr Ala Ala His Ser Leu Pro Gln Gln Thr Lys Lys Pro Glu Ser
                 215                 220                 225

 Glu Gly Tyr Leu Gln Glu Glu Lys Gln Lys Cys Tyr Asn Asp Leu
                 230                 235                 240

 Leu Ala Ser Ala Lys Lys Asp Leu Glu Val Glu Arg Gln Thr Ile
                 245                 250                 255

 Thr Gln Leu Ser Phe Glu Leu Ser Glu Phe Arg Arg Lys Tyr Glu
                 260                 265                 270

 Glu Thr Gln Lys Glu Val His Asn Leu Asn Gln Leu Leu Tyr Ser
                 275                 280                 285

 Gln Arg Arg Ala Asp Val Gln His Leu Glu Asp Asp Arg His Lys
                 290                 295                 300

 Thr Glu Lys Ile Gln Lys Leu Arg Glu Glu Asn Asp Ile Ala Arg
                 305                 310                 315

 Gly Lys Leu Glu Glu Glu Lys Lys Arg Ser Glu Glu Leu Leu Ser
                 320                 325                 330

 Gln Val Gln Phe Leu Tyr Thr Ser Leu Leu Lys Gln Gln Glu Glu
                 335                 340                 345

 Gln Thr Arg Val Ala Leu Leu Glu Gln Gln Met Gln Ala Cys Thr
                 350                 355                 360

 Leu Asp Phe Glu Asn Glu Lys Leu Asp Arg Gln His Val Gln His
                 365                 370                 375

 Gln Leu Leu Val Ile Leu Lys Glu Leu Arg Lys Ala Arg Asn Gln
                 380                 385                 390

 Ile Thr Gln Leu Glu Ser Leu Lys Gln Leu His Glu Phe Ala Ile
                 395                 400                 405

 Thr Glu Pro Leu Val Thr Phe Gln Gly Glu Thr Glu Asn Arg Glu
                 410                 415                 420

 Lys Val Ala Ala Ser Pro Lys Ser Pro Thr Ala Ala Leu Asn Glu
                 425                 430                 435

 Ser Leu Val Glu Cys Pro Lys Cys Asn Ile Gln Tyr Pro Ala Thr
                 440                 445                 450

 Glu His Arg Asp Leu Leu Val His Val Glu Tyr Cys Ser Lys
                 455                 460

<210> 3233
<211> 3471
<212> DNA
<213> Homo sapien

<400> 3233
 gtgagccgtc tacgaagccc gggcttggcc tgggcgacac tgagcggctt 50

 taaccggcgg cgtccagccg gctccgccag cgctgccgcc gccctcgagg 100

 ctccctctga ctgaaggcgc gctgagcatc gcggcattag gggctcctgg 150

 tccctcaaac atccagggaa gccattttca gggactaggt actgaccccc 200

 gcgagccgcc acagccacag cccgcgctcc gggccgaacg cccgagctca 250

 agagctcccg agcttccgtc gggcggcggc ctcacagctg ggggccctga 300

 ggcggaaggc gcagccgctc agctgcggac cgggggcgtg gcgagggcgc 350

 acaggttctg tttttcgccg gcccggggcc gctttcggtt tcgtttcccg 400

 ccggcgtctc caccctgcga gagccgcccg ccagccagcg tccgccgccg 450

 tccgcgtcgc gccacccgcg gtccgacggg agcaggccca gcggccatgg 500

 cccaggccgg cgtcgtcggt gaggtcaccc aggtgctgtg cgcggccggg 550

 ggcgccctgg agttgcccga gctgcggcgc cgcttgcgga tgggcttgag 600

 cgccgacgcg ctggagcggc tgctgcggca gcgtgggcgc ttcgtggtgg 650

 cggtgcgggc gggcggcgca gccgcggccc cggagcgcgt ggtgctggcc 700

 gcctcgccgc tgcgcctgtg tcgcgcgcac cagggctcca agccgggctg 750

 cgtggggctc tgcgcgcagc tccacctctg caggttcatg gtctacggcg 800

 cctgcaagtt cctgagagcc gggaagaact gtaggaatag tcacagcttg 850

 acaaccgaac acaacctgag tgtgctgaga actcatggcg ttgaccacct 900

 gagctataat gagctatgcc aactcttgtt tcagaacgac ccctggcttt 950

 tgccagaaat ttgccaacat tacaacaaag gagatggacc ccacggctct 1000

 tgtgcctttc aaaagcagtg catcaagctc catatctgcc agtatttttt 1050

 acagggggaa tgcaagtttg gcactagctg taagagatcc catgatttct 1100

 ctaattctga gaatctggaa aaattggaga agttgggtat gagctcagac 1150

 ctggtgagca ggctgcctac catttataga aatgcacatg acatcaagaa 1200

 taagagctct gcccccagca gagtgcctcc tctttttgtc ccacagggga 1250

 cttctgaaag aaaagacagt tcaggttctg tgtccccaaa cactcttagc 1300

 caggaggagg gtgatcagat ctgtttgtac catatccgga aaagttgtag 1350

 ctttcaagat aagtgccata gagttcattt ccatttgccg tatcgatggc 1400

 aattcttgga tagaggcaaa tgggaggatt tggacaacat ggaacttatt 1450

 gaagaggcat attgcaatcc caaaatagaa aggatcctgt gctctgagtc 1500

 agccagtacc tttcactctc attgtctgaa ctttaacgcc atgacttacg 1550

 gtgctaccca ggctcgccgc ctctccacgg cctcctctgt caccaaacct 1600

 ccacacttca tcctcaccac tgactggatt tggtactgga gtgatgagtt 1650

 tggttcttgg caggaatatg gaagacaggg cacggtgcac cctgtgacca 1700

 ctgtcagcag tagcgacgtg gagaaggcct acctggccta ctgtacaccg 1750

 gggtctgacg gccaggcagc caccttgaag ttccaggccg gaaagcacaa 1800

 ctacgagtta gatttcaaag ccttcgttca gaaaaacctg gtctatggca 1850

 caactaaaaa ggtttgccgc agacccaaat acgtgtctcc ccaggatgtg 1900

 acgaccatgc aaacctgcaa taccaagttt ccaggcccga agagcatccc 1950

 agactattgg gactcctctg ccctgccaga cccaggcttt cagaagatca 2000

 cccttagttc ttcctcggaa gagtatcaga aggtctggaa cctctttaac 2050

 cgcacgctgc ctttttactt tgttcagaag attgagcgag tacagaacct 2100

 ggccctctgg gaagtctacc agtggcaaaa aggacagatg cagaagcaga 2150

 acggagggaa ggccgtggac gagcggcagc tgttccacgg caccagcgcc 2200

 atttttgtgg acgccatctg ccagcagaac tttgactggc gggtctgtgg 2250

 tgttcatggc acttcctacg gcaaggggag ctactttgcc cgagatgctg 2300

 catattccca ccactacagc aaatccgaca cgcagaccca cacgatgttc 2350

 ctggcccggg tgctggtggg cgagttcgtc aggggcaatg cctcctttgt 2400

 ccgtccaccg gccaaggagg gctggagcaa cgccttctat gatagctgcg 2450

 tgaacagtgt gtccgacccc tccatctttg tgatctttga gaaacaccag 2500

 gtctacccag agtatgtcat ccagtacacc acctcctcca agccctcggt 2550

 cacaccctcc atcctgctgg ccttgggctc cctgttcagc agccgacagt 2600

 gagtgcacag gagtgttcca ggcctttcac ctgctctgcc ttgaaatggc 2650

 tatttgggcc tttccttttc tttttaaaca gaaactttta atgaactgtt 2700

 ctcttaacat tgacctctca atgaagttat gttcttaatc tcttgctaat 2750

 aatgattttt acttttaagt cacttttggg ttcactagtg gactaaccag 2800

 aagtgattgt agttgagtcc agttttgctt tttaataatg tgttgaagtt 2850

 ttagttttta ctctttgttg actttgctgc ttattggcac cagggacaga 2900

 gtttctagat acaattttat ggattggttt taatttttat gagtttgtct 2950

 ctgcagtgat tcggtttctc agagtctcat ggcatcatag tttttccaga 3000

 atgacacagt agccaccggt ggatgacagc ccacgggcgg cacagtcact 3050

 tctgcctgtt gctctgacac caacccaggc agctctgctg tggcttctcc 3100

 tgggctctgg cattagttgg tctgtgtcac attgtcagaa caggtggctg 3150

 ctgtgtggtg ccatcgagtc cctgctggtt ccccttgtcc tgggagggtc 3200

 acccattgcc caaggaagtg catccacctg gcaggtgacc tggaggagta 3250

 gcttccccga ggacccccag gcttggcctg tgattgcgca aacccacatt 3300

 tcctaagcac actggacacc cttcgagtgt gggttttaac atccctgtga 3350

 gattgaatac ttgtgccaca catgtcacaa aagagtatgg aaataaaaga 3400

 aaatttatcc gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3450

 aaaaaaaaaa aaaaaaaaaa a 3471

<210> 3234
<211> 701
<212> PRT
<213> Homo sapien

<400> 3234
 Met Ala Gln Ala Gly Val Val Gly Glu Val Thr Gln Val Leu Cys
   1               5                  10                  15

 Ala Ala Gly Gly Ala Leu Glu Leu Pro Glu Leu Arg Arg Arg Leu
                  20                  25                  30

 Arg Met Gly Leu Ser Ala Asp Ala Leu Glu Arg Leu Leu Arg Gln
                  35                  40                  45

 Arg Gly Arg Phe Val Val Ala Val Arg Ala Gly Gly Ala Ala Ala
                  50                  55                  60

 Ala Pro Glu Arg Val Val Leu Ala Ala Ser Pro Leu Arg Leu Cys
                  65                  70                  75

 Arg Ala His Gln Gly Ser Lys Pro Gly Cys Val Gly Leu Cys Ala
                  80                  85                  90

 Gln Leu His Leu Cys Arg Phe Met Val Tyr Gly Ala Cys Lys Phe
                  95                 100                 105

 Leu Arg Ala Gly Lys Asn Cys Arg Asn Ser His Ser Leu Thr Thr
                 110                 115                 120

 Glu His Asn Leu Ser Val Leu Arg Thr His Gly Val Asp His Leu
                 125                 130                 135

 Ser Tyr Asn Glu Leu Cys Gln Leu Leu Phe Gln Asn Asp Pro Trp
                 140                 145                 150

 Leu Leu Pro Glu Ile Cys Gln His Tyr Asn Lys Gly Asp Gly Pro
                 155                 160                 165

 His Gly Ser Cys Ala Phe Gln Lys Gln Cys Ile Lys Leu His Ile
                 170                 175                 180

 Cys Gln Tyr Phe Leu Gln Gly Glu Cys Lys Phe Gly Thr Ser Cys
                 185                 190                 195

 Lys Arg Ser His Asp Phe Ser Asn Ser Glu Asn Leu Glu Lys Leu
                 200                 205                 210

 Glu Lys Leu Gly Met Ser Ser Asp Leu Val Ser Arg Leu Pro Thr
                 215                 220                 225

 Ile Tyr Arg Asn Ala His Asp Ile Lys Asn Lys Ser Ser Ala Pro
                 230                 235                 240

 Ser Arg Val Pro Pro Leu Phe Val Pro Gln Gly Thr Ser Glu Arg
                 245                 250                 255

 Lys Asp Ser Ser Gly Ser Val Ser Pro Asn Thr Leu Ser Gln Glu
                 260                 265                 270

 Glu Gly Asp Gln Ile Cys Leu Tyr His Ile Arg Lys Ser Cys Ser
                 275                 280                 285

 Phe Gln Asp Lys Cys His Arg Val His Phe His Leu Pro Tyr Arg
                 290                 295                 300

 Trp Gln Phe Leu Asp Arg Gly Lys Trp Glu Asp Leu Asp Asn Met
                 305                 310                 315

 Glu Leu Ile Glu Glu Ala Tyr Cys Asn Pro Lys Ile Glu Arg Ile
                 320                 325                 330

 Leu Cys Ser Glu Ser Ala Ser Thr Phe His Ser His Cys Leu Asn
                 335                 340                 345

 Phe Asn Ala Met Thr Tyr Gly Ala Thr Gln Ala Arg Arg Leu Ser
                 350                 355                 360

 Thr Ala Ser Ser Val Thr Lys Pro Pro His Phe Ile Leu Thr Thr
                 365                 370                 375

 Asp Trp Ile Trp Tyr Trp Ser Asp Glu Phe Gly Ser Trp Gln Glu
                 380                 385                 390

 Tyr Gly Arg Gln Gly Thr Val His Pro Val Thr Thr Val Ser Ser
                 395                 400                 405

 Ser Asp Val Glu Lys Ala Tyr Leu Ala Tyr Cys Thr Pro Gly Ser
                 410                 415                 420

 Asp Gly Gln Ala Ala Thr Leu Lys Phe Gln Ala Gly Lys His Asn
                 425                 430                 435

 Tyr Glu Leu Asp Phe Lys Ala Phe Val Gln Lys Asn Leu Val Tyr
                 440                 445                 450

 Gly Thr Thr Lys Lys Val Cys Arg Arg Pro Lys Tyr Val Ser Pro
                 455                 460                 465

 Gln Asp Val Thr Thr Met Gln Thr Cys Asn Thr Lys Phe Pro Gly
                 470                 475                 480

 Pro Lys Ser Ile Pro Asp Tyr Trp Asp Ser Ser Ala Leu Pro Asp
                 485                 490                 495

 Pro Gly Phe Gln Lys Ile Thr Leu Ser Ser Ser Ser Glu Glu Tyr
                 500                 505                 510

 Gln Lys Val Trp Asn Leu Phe Asn Arg Thr Leu Pro Phe Tyr Phe
                 515                 520                 525

 Val Gln Lys Ile Glu Arg Val Gln Asn Leu Ala Leu Trp Glu Val
                 530                 535                 540

 Tyr Gln Trp Gln Lys Gly Gln Met Gln Lys Gln Asn Gly Gly Lys
                 545                 550                 555

 Ala Val Asp Glu Arg Gln Leu Phe His Gly Thr Ser Ala Ile Phe
                 560                 565                 570

 Val Asp Ala Ile Cys Gln Gln Asn Phe Asp Trp Arg Val Cys Gly
                 575                 580                 585

 Val His Gly Thr Ser Tyr Gly Lys Gly Ser Tyr Phe Ala Arg Asp
                 590                 595                 600

 Ala Ala Tyr Ser His His Tyr Ser Lys Ser Asp Thr Gln Thr His
                 605                 610                 615

 Thr Met Phe Leu Ala Arg Val Leu Val Gly Glu Phe Val Arg Gly
                 620                 625                 630

 Asn Ala Ser Phe Val Arg Pro Pro Ala Lys Glu Gly Trp Ser Asn
                 635                 640                 645

 Ala Phe Tyr Asp Ser Cys Val Asn Ser Val Ser Asp Pro Ser Ile
                 650                 655                 660

 Phe Val Ile Phe Glu Lys His Gln Val Tyr Pro Glu Tyr Val Ile
                 665                 670                 675

 Gln Tyr Thr Thr Ser Ser Lys Pro Ser Val Thr Pro Ser Ile Leu
                 680                 685                 690

 Leu Ala Leu Gly Ser Leu Phe Ser Ser Arg Gln
                 695                 700

<210> 3235
<211> 1126
<212> DNA
<213> Homo sapien

<400> 3235
 agccgagacg gtgcagggcc ggagaagcac cttcactccc agcctgcgcc 50

 ccgatgctgc gcgttctgtg cctcctgcgc ccctggaggc cccttcgggc 100

 ccgcggctgc gcttccgacg gggcggccgg gggctcagag atccaagtgc 150

 gcgccctggc gggtccggac caagggatca ctgagattct gatgaacaga 200

 ccttctgccc gcaatgcctt ggggaatgtc ttcgtcagtg agctgctgga 250

 aactctggcc cagctgcggg aggaccggca agtgcgtgtc ctgctcttca 300

 gaagtggagt gaagggcgcg ttctgtgcag gtgcagacct gaaggagcgg 350

 gaacagatga gtgaagcaga ggtgggggtg tttgtccagc gactccgggg 400

 cctgatgaat gacatcgctt cctcggcagt catgggactg attgagacca 450

 cgcgagggct cctcccgggg gcaggaggga ctcagaggct gccccgttgt 500

 ctgggggtgg ccctggcgaa ggagctcatc ttcacgggcc gacgactgag 550

 tggaactgag gcccacgtac tggggctggt gaatcacgct gtggcccaga 600

 acgaggaggg ggacgccgcc taccagcggg cacgagcact ggcccaggag 650

 atcctgcccc aggcccccat tgccgtgcgg ctgggcaaag tagccattaa 700

 ccgaggaacg gaggtggaca ttgcatctgg gatggccatt gaagggatgt 750

 gctatgccca gaatattcca acccgggacc ggctagaggg catggcagcc 800

 ttcagggaga agcggactcc caaatttgtt ggcaaatgac ccccatttta 850

 accttcagca tgggagatgc atgccctgaa gagcaggatc cagaaggaag 900

 atttgtggcc agattgcctt catcatttca cctctccaga cttccatttc 950

 ttcacaagga tgatgatgga aataaaatga ctggcgtgat gcctggaacc 1000

 aaggtgctga tcctaccacc tactgctacc ttccttagct tcaccctggc 1050

 tagaaataat cacgagggtt gggtttgctt tggaaaatgc ctgtctctct 1100

 acttgaatga taaagaatta aattag 1126

<210> 3236
<211> 261
<212> PRT
<213> Homo sapien

<400> 3236
 Met Leu Arg Val Leu Cys Leu Leu Arg Pro Trp Arg Pro Leu Arg
   1               5                  10                  15

 Ala Arg Gly Cys Ala Ser Asp Gly Ala Ala Gly Gly Ser Glu Ile
                  20                  25                  30

 Gln Val Arg Ala Leu Ala Gly Pro Asp Gln Gly Ile Thr Glu Ile
                  35                  40                  45

 Leu Met Asn Arg Pro Ser Ala Arg Asn Ala Leu Gly Asn Val Phe
                  50                  55                  60

 Val Ser Glu Leu Leu Glu Thr Leu Ala Gln Leu Arg Glu Asp Arg
                  65                  70                  75

 Gln Val Arg Val Leu Leu Phe Arg Ser Gly Val Lys Gly Ala Phe
                  80                  85                  90

 Cys Ala Gly Ala Asp Leu Lys Glu Arg Glu Gln Met Ser Glu Ala
                  95                 100                 105

 Glu Val Gly Val Phe Val Gln Arg Leu Arg Gly Leu Met Asn Asp
                 110                 115                 120

 Ile Ala Ser Ser Ala Val Met Gly Leu Ile Glu Thr Thr Arg Gly
                 125                 130                 135

 Leu Leu Pro Gly Ala Gly Gly Thr Gln Arg Leu Pro Arg Cys Leu
                 140                 145                 150

 Gly Val Ala Leu Ala Lys Glu Leu Ile Phe Thr Gly Arg Arg Leu
                 155                 160                 165

 Ser Gly Thr Glu Ala His Val Leu Gly Leu Val Asn His Ala Val
                 170                 175                 180

 Ala Gln Asn Glu Glu Gly Asp Ala Ala Tyr Gln Arg Ala Arg Ala
                 185                 190                 195

 Leu Ala Gln Glu Ile Leu Pro Gln Ala Pro Ile Ala Val Arg Leu
                 200                 205                 210

 Gly Lys Val Ala Ile Asn Arg Gly Thr Glu Val Asp Ile Ala Ser
                 215                 220                 225

 Gly Met Ala Ile Glu Gly Met Cys Tyr Ala Gln Asn Ile Pro Thr
                 230                 235                 240

 Arg Asp Arg Leu Glu Gly Met Ala Ala Phe Arg Glu Lys Arg Thr
                 245                 250                 255

 Pro Lys Phe Val Gly Lys
                 260

<210> 3237
<211> 1113
<212> DNA
<213> Homo sapien

<400> 3237
 ttctcaccgc tgctatggag gcgctggcca tgggttcccg ggcgctgcgg 50

 ctctggctgg tcgcacccgg tggcgggatc aaatggagat ttatagcaac 100

 atcgccagct tctcagctgt caccgacaga attgacagaa atgcggaatg 150

 atctctttaa taaagagaaa gccaggcagt tatcattaac tccccgaact 200

 gagaagatag aagttaagca tgttgggaaa actgaccccg gtactgtctt 250

 cgtgatgaat aaaaacattt caactcccta cagttgtgcc atgcatttaa 300

 gcgagtggta ttgcaggaag tccattctgg ctctggtgga tggacagcct 350

 tgggacatgt ataagccttt aacaaagtcc tgtgaaatta aatttcttac 400

 tttcaaagat tgtgatccag gagaagtgaa taaggcatat tggcgttcct 450

 gtgctatgat gatgggctgt gtgatagaga gggcattcaa agatgaatat 500

 atggtcaatt tggtcagagc tccagaagtt cctgtaattt ctggtgcctt 550

 ctgttatgac gtagttttgg atagcaaact tgatgagtgg atgccaacaa 600

 aagagaactt acgttccttc acaaaggatg ctcatgcttt aatttataaa 650

 gatcttccat ttgaaactct ggaagttgaa gcaaaagtgg cattggaaat 700

 atttcaacac agcaagtaca aagtagattt catagaagag aaggcatctc 750

 agaaccctga gagaatagtc aagctacaca gaataggtga cttcattgat 800

 gtgagtgagg gccctcttat tccaagaaca agtatttgtt tccagtatga 850

 agtgtcagca gttcacaatc ttcaacccac ccagccaagt ctcatacgaa 900

 gattccaggg tgtgtcttta cctgttcact taagagcaca ttttacaata 950

 tgggataagc tattggaaag atctcggaaa atggtaactg aagatcaaag 1000

 taaagcaaca gaggaatgta catctaccta ataactttct aaaatttaaa 1050

 tatgtataat aaaataaatg ttttaaatat aaaaaaaaaa aaaaaaaaaa 1100

 aaaaaaaaaa aaa 1113

<210> 3238
<211> 258
<212> PRT
<213> Homo sapien

<400> 3238
 Met Asn Lys Asn Ile Ser Thr Pro Tyr Ser Cys Ala Met His Leu
   1               5                  10                  15

 Ser Glu Trp Tyr Cys Arg Lys Ser Ile Leu Ala Leu Val Asp Gly
                  20                  25                  30

 Gln Pro Trp Asp Met Tyr Lys Pro Leu Thr Lys Ser Cys Glu Ile
                  35                  40                  45

 Lys Phe Leu Thr Phe Lys Asp Cys Asp Pro Gly Glu Val Asn Glu
                  50                  55                  60

 Ala Tyr Trp Arg Ser Cys Ala Met Met Met Gly Cys Val Ile Glu
                  65                  70                  75

 Arg Ala Phe Lys Asp Glu Tyr Met Val Asn Leu Val Arg Ala Pro
                  80                  85                  90

 Glu Val Pro Val Ile Ser Gly Ala Phe Cys Tyr Asp Val Val Leu
                  95                 100                 105

 Asp Ser Lys Leu Asp Glu Trp Met Pro Thr Lys Glu Asn Leu Arg
                 110                 115                 120

 Ser Phe Thr Lys Asp Ala His Ala Leu Ile Tyr Lys Asp Leu Pro
                 125                 130                 135

 Phe Glu Thr Leu Glu Val Glu Ala Lys Val Ala Leu Glu Ile Phe
                 140                 145                 150

 Gln His Ser Lys Tyr Lys Val Asp Phe Ile Glu Glu Lys Ala Ser
                 155                 160                 165

 Gln Asn Pro Glu Arg Ile Val Lys Leu His Arg Ile Gly Asp Phe
                 170                 175                 180

 Ile Asp Val Ser Glu Gly Pro Leu Ile Pro Arg Thr Ser Ile Cys
                 185                 190                 195

 Phe Gln Tyr Glu Val Ser Ala Val His Asn Leu Gln Pro Thr Gln
                 200                 205                 210

 Pro Ser Leu Ile Arg Arg Phe Gln Gly Val Ser Leu Pro Val His
                 215                 220                 225

 Leu Arg Ala His Phe Thr Ile Trp Asp Lys Leu Leu Glu Arg Ser
                 230                 235                 240

 Arg Lys Met Val Thr Glu Asp Gln Ser Lys Ala Thr Glu Glu Cys
                 245                 250                 255

 Thr Ser Thr


<210> 3239
<211> 2058
<212> DNA
<213> Homo sapien

<400> 3239
 cggtgctagc gacacgggag tggcaaacgc atcctcttgc cgttcccggt 50

 gtttgggcct tgcctgtgac ggtgggaaaa gaaaatggcc ttgctgtgct 100

 acaaccgggg ctgcggtcag cgcttcgatc ctgagaccaa ttccgacgat 150

 gcttgcacat accacccagg tgttccggtc tttcacgatg cattaaaggg 200

 ttggtcttgc tgtaagagaa gaacaactga tttttctgat ttcttaagca 250

 ttgtaggctg tacaaaaggt agacataata gtgagaagcc acctgagcca 300

 gtcaaacctg aagtcaagac tactgagaag aaggagctat gtgaattaaa 350

 acccaaattt caggaacaca tcattcaagc ccctaagcca gtagaagcaa 400

 taaaaagacc aagcccagat gaaccaatga caaatttgga attaaaaata 450

 tctgcctccc taaaacaagc acttgataaa cttaaactgt catcagggaa 500

 tgaagaaaat aagaaagaag aagacaatga tgaaattaag attgggacct 550

 catgtaagaa tggagggtgt tcaaagacat accagggtct agagagtcta 600

 gaagaagtct gtgtatatca ttctggagta cctattttcc atgaggggat 650

 gaaatactgg agctgttgta gaagaaaaac ttctgatttt aatacattct 700

 tagcccaaga gggctgtaca aaagggaaac acatgtggac taaaaaagat 750

 gctgggaaaa aagttgttcc atgtagacat gacttgcatc agactggagg 800

 tgaagttacc atttcagtat atgctaaaaa ctcacttcca gaacttagcc 850

 gagtagaagc aaatagcaca ttgttaaatg tcattattgt atttgaagga 900

 gagaaggaat ttgatcaaaa tgtgaaatta tggggtgtga ttgatgtaaa 950

 gcgaagttat gtaactatga ctgcaacaaa gattgaaatc actatgagaa 1000

 aagctgaacc gatgcagtgg gcaagccttg aactgcctgc agctaaaaag 1050

 caggaaaaac aaaaagatga cacaacagat tgagtgggag atggaaggaa 1100

 ggctattaca ttatttccga atttttaata ctgtgtgaag tggtggcttg 1150

 ctgctgtaat cttttgtttt gttgttgtgt tactgaatgt ggcatttcag 1200

 ggttaacatt aggttcttaa aagccaaagt cagtttgtct ttttgtgcct 1250

 ctcatctttc ttttgtgtta tgtaagattg attattcatt tctccctact 1300

 ggtaggaacc atagttgtgt cctatacttg aagaggctgg aaagtagccc 1350

 ataaccataa ttgcagtatt tctttgtatt tctctgttaa gcaaagaaat 1400

 attaaggaac atttttttta tgtttttgta ttattccata attagtaaag 1450

 caagatgaaa tgtcaaattt taatcagttt tttcatggat ttgtgttctt 1500

 acagtacttg aaaatattta aggaagagat gaagctctgc agttttttct 1550

 atgtgggatg attacttttt taaggaggat taattctgag gtagtatagt 1600

 aactaaaggg gaatatatga attgtttaac aaattagaat ttgtttacaa 1650

 ctacttgaat ttttaaatta tgtcaaaact tacattactt gccaagcagt 1700

 atgatgttat aggaaacata aataagatta cagaggtatc aatttggtta 1750

 aaattcacca ttttataaga ctaagcaata atcttaacaa cctctttcct 1800

 gaatatttaa atgtgtttgt atggtgttat gactaattgt tactgattta 1850

 gagactaagc cctcttaaaa cctttagtta aatataaaaa gaaattatat 1900

 atatcttgcc tccctgatgg aaaactatat aaaattgtag acttaaaagg 1950

 tttgtggaaa tacattagga tatcagaaaa ctaaatatat ggagttgctt 2000

 tatgactatt acatgttaaa taaaaatagc ttaattgtta aaaaaaaaaa 2050

 aaaaaaaa 2058

<210> 3240
<211> 332
<212> PRT
<213> Homo sapien

<400> 3240
 Met Ala Leu Leu Cys Tyr Asn Arg Gly Cys Gly Gln Arg Phe Asp
   1               5                  10                  15

 Pro Glu Thr Asn Ser Asp Asp Ala Cys Thr Tyr His Pro Gly Val
                  20                  25                  30

 Pro Val Phe His Asp Ala Leu Lys Gly Trp Ser Cys Cys Lys Arg
                  35                  40                  45

 Arg Thr Thr Asp Phe Ser Asp Phe Leu Ser Ile Val Gly Cys Thr
                  50                  55                  60

 Lys Gly Arg His Asn Ser Glu Lys Pro Pro Glu Pro Val Lys Pro
                  65                  70                  75

 Glu Val Lys Thr Thr Glu Lys Lys Glu Leu Cys Glu Leu Lys Pro
                  80                  85                  90

 Lys Phe Gln Glu His Ile Ile Gln Ala Pro Lys Pro Val Glu Ala
                  95                 100                 105

 Ile Lys Arg Pro Ser Pro Asp Glu Pro Met Thr Asn Leu Glu Leu
                 110                 115                 120

 Lys Ile Ser Ala Ser Leu Lys Gln Ala Leu Asp Lys Leu Lys Leu
                 125                 130                 135

 Ser Ser Gly Asn Glu Glu Asn Lys Lys Glu Glu Asp Asn Asp Glu
                 140                 145                 150

 Ile Lys Ile Gly Thr Ser Cys Lys Asn Gly Gly Cys Ser Lys Thr
                 155                 160                 165

 Tyr Gln Gly Leu Glu Ser Leu Glu Glu Val Cys Val Tyr His Ser
                 170                 175                 180

 Gly Val Pro Ile Phe His Glu Gly Met Lys Tyr Trp Ser Cys Cys
                 185                 190                 195

 Arg Arg Lys Thr Ser Asp Phe Asn Thr Phe Leu Ala Gln Glu Gly
                 200                 205                 210

 Cys Thr Lys Gly Lys His Met Trp Thr Lys Lys Asp Ala Gly Lys
                 215                 220                 225

 Lys Val Val Pro Cys Arg His Asp Leu His Gln Thr Gly Gly Glu
                 230                 235                 240

 Val Thr Ile Ser Val Tyr Ala Lys Asn Ser Leu Pro Glu Leu Ser
                 245                 250                 255

 Arg Val Glu Ala Asn Ser Thr Leu Leu Asn Val Ile Ile Val Phe
                 260                 265                 270

 Glu Gly Glu Lys Glu Phe Asp Gln Asn Val Lys Leu Trp Gly Val
                 275                 280                 285

 Ile Asp Val Lys Arg Ser Tyr Val Thr Met Thr Ala Thr Lys Ile
                 290                 295                 300

 Glu Ile Thr Met Arg Lys Ala Glu Pro Met Gln Trp Ala Ser Leu
                 305                 310                 315

 Glu Leu Pro Ala Ala Lys Lys Gln Glu Lys Gln Lys Asp Asp Thr
                 320                 325                 330

 Thr Asp


<210> 3241
<211> 2794
<212> DNA
<213> Homo sapien

<400> 3241
 gaccagccgt gcaaatctct agaagatgac ggtgttcttt aaaacgcttc 50

 gaaatcactg gaagaaaact acagctgggc tctgcctgct gacctgggga 100

 ggccattggc tctatggaaa acactgtgat aacctcctaa ggagagcagc 150

 ctgtcaagaa gctcaggtgt ttggcaatca actcattcct cccaatgcac 200

 aagtgaagaa ggccactgtt tttctcaatc ctgcagcttg caaaggaaaa 250

 gctaggactc tatttgaaaa aaatgctgcc ccgattttac atttatctgg 300

 catggatgtg actattgtta agacagatta tgagggacaa gccaagaaac 350

 tcctggaact gatggaaaac acggatgtga tcattgttgc aggaggagat 400

 gggacactgc aggaggttgt tactggtgtt cttcgacgaa cagatgaggc 450

 taccttcagt aagattccca ttggatttat cccactggga gagaccagta 500

 gtttgagtca taccctcttt gccgaaagtg gaaacaaagt ccaacatatt 550

 actgatgcca cacttgccat tgtgaaagga gagacagttc cacttgatgt 600

 cttgcagatc aagggtgaaa aggaacagcc tgtatttgca atgaccggcc 650

 ttcgatgggg atctttcaga gatgctggcg tcaaagttag caagtactgg 700

 tatcttgggc ctctaaaaat caaagcagcc cactttttca gcactcttaa 750

 ggagtggcct cagactcatc aagcctctat ctcatacacg ggacctacag 800

 agagacctcc caatgaacca gaggagaccc ctgtacaaag gccttctttg 850

 tacaggagaa tattacgaag gcttgcgtcc tactgggcac aaccacagga 900

 tgccctttcc caagaggtga gcccggaggt ctggaaagat gtgcagctgt 950

 ccaccattga actgtccatc acaacacgga ataatcagct tgacccgaca 1000

 agcaaagaag attttctgaa tatctgcatt gaacctgaca ccatcagcaa 1050

 aggagacttt ataactatag gaagtcgaaa ggtgagaaac cccaagctgc 1100

 acgtggaggg cacggagtgt ctccaagcca gccagtgcac tttgcttatc 1150

 ccggagggag cagggggctc ttttagcatt gacagtgagg agtatgaagc 1200

 gatgcctgtg gaggtgaaac tgctccccag gaagctgcag ttcttctgtg 1250

 atcctaggaa gagagaacag atgctcacaa gccccaccca gtgagcagca 1300

 gaagacaagc actctgagac cacactttag gccaccggtg ggaccaaaag 1350

 ggaacaggtg cctcagccat cccaacagtg tcgtcagagg gtccccaggg 1400

 cattttcatg gcaagtaccc ctctgccccc actccagcag tgcttcccaa 1450

 agtgtgctct gtcacctgct ttgcaatcgg cttccattag cgcatgtttt 1500

 attttggtgt gacggttggc cctcctaaac acggactttc ctcaggctgg 1550

 ttcaagacgg aaaaggactt tcttctgttt tcttccaaag tgcaaccaca 1600

 gtggagagcc cacggtgggc ttagcctgcc taggcccttc catttctctt 1650

 ctttgaccgt gctaggaatt ccaggaaagt gcattcctgc cctggtgacc 1700

 ttttcctatg tctaggctcc tccacaggtg ctgctatttt gtgagctccg 1750

 gctcctgttt agcttttatt tcagttctaa cctcagtcca gaaacatatg 1800

 tgaggttgtt tccctcttca gccacggcta caataccgga aaatgctagt 1850

 ttttatttat ttttttaagt agtgcttcct aaatggtttg catgagagcc 1900

 acctggggta catgttgaaa acttatttgg ggtctacccc aaacctaata 1950

 acccaaattt ggggatgggg cccaggaata tgcattttta aaaagtcatc 2000

 tgcccttccc aggtgattct gtaagttgtc cctcaactgt acttggagaa 2050

 atcgtgtttt aaagcagtag tccacaaagt attctgctca tgtgccccca 2100

 aaagtatttt gaaaaatcat gtataccctc acccatctaa gttgatatct 2150

 aaaattttat ctaagttggt atctaaaatt tttcatggga agttaaatag 2200

 ttgacaaagt atgtatttgc tggtgtcgtg taaatattgg tattttaaaa 2250

 taaaaactgt tacatcacta ttttaaacat atccagtaca atttaaatat 2300

 cacaacaatt tgacaccctt cattcattta taaaaataaa tgagctagtt 2350

 ctttagtagt taaacatttc aaattggctt ttctccttct gtatttccat 2400

 accacttttc agccaagaat cctatcataa tgtaatctat tatgcccgac 2450

 atcttttaat cattcacccc attacttctt gtcaacaaaa aatataaatg 2500

 gaaatttttt ttttagctct tgctttaagt gtttgtttgt tatctcagtc 2550

 cagaaccaat attatcgtaa ttaattattg gtatataatg aaaacggtat 2600

 taattcttgg atgattaaaa gtttttttat tagaatgttc tttatcctaa 2650

 ttagttcatt tatccaagaa tacatgaatg tgatttacag ctgagatggg 2700

 gttcaacctc agctgtattc cttgtttctg tatagatgta agcacataaa 2750

 ttcgatggaa tagaattacg ttaacaatga aaaaaaaaaa aaaa 2794

<210> 3242
<211> 422
<212> PRT
<213> Homo sapien

<400> 3242
 Met Thr Val Phe Phe Lys Thr Leu Arg Asn His Trp Lys Lys Thr
   1               5                  10                  15

 Thr Ala Gly Leu Cys Leu Leu Thr Trp Gly Gly His Trp Leu Tyr
                  20                  25                  30

 Gly Lys His Cys Asp Asn Leu Leu Arg Arg Ala Ala Cys Gln Glu
                  35                  40                  45

 Ala Gln Val Phe Gly Asn Gln Leu Ile Pro Pro Asn Ala Gln Val
                  50                  55                  60

 Lys Lys Ala Thr Val Phe Leu Asn Pro Ala Ala Cys Lys Gly Lys
                  65                  70                  75

 Ala Arg Thr Leu Phe Glu Lys Asn Ala Ala Pro Ile Leu His Leu
                  80                  85                  90

 Ser Gly Met Asp Val Thr Ile Val Lys Thr Asp Tyr Glu Gly Gln
                  95                 100                 105

 Ala Lys Lys Leu Leu Glu Leu Met Glu Asn Thr Asp Val Ile Ile
                 110                 115                 120

 Val Ala Gly Gly Asp Gly Thr Leu Gln Glu Val Val Thr Gly Val
                 125                 130                 135

 Leu Arg Arg Thr Asp Glu Ala Thr Phe Ser Lys Ile Pro Ile Gly
                 140                 145                 150

 Phe Ile Pro Leu Gly Glu Thr Ser Ser Leu Ser His Thr Leu Phe
                 155                 160                 165

 Ala Glu Ser Gly Asn Lys Val Gln His Ile Thr Asp Ala Thr Leu
                 170                 175                 180

 Ala Ile Val Lys Gly Glu Thr Val Pro Leu Asp Val Leu Gln Ile
                 185                 190                 195

 Lys Gly Glu Lys Glu Gln Pro Val Phe Ala Met Thr Gly Leu Arg
                 200                 205                 210

 Trp Gly Ser Phe Arg Asp Ala Gly Val Lys Val Ser Lys Tyr Trp
                 215                 220                 225

 Tyr Leu Gly Pro Leu Lys Ile Lys Ala Ala His Phe Phe Ser Thr
                 230                 235                 240

 Leu Lys Glu Trp Pro Gln Thr His Gln Ala Ser Ile Ser Tyr Thr
                 245                 250                 255

 Gly Pro Thr Glu Arg Pro Pro Asn Glu Pro Glu Glu Thr Pro Val
                 260                 265                 270

 Gln Arg Pro Ser Leu Tyr Arg Arg Ile Leu Arg Arg Leu Ala Ser
                 275                 280                 285

 Tyr Trp Ala Gln Pro Gln Asp Ala Leu Ser Gln Glu Val Ser Pro
                 290                 295                 300

 Glu Val Trp Lys Asp Val Gln Leu Ser Thr Ile Glu Leu Ser Ile
                 305                 310                 315

 Thr Thr Arg Asn Asn Gln Leu Asp Pro Thr Ser Lys Glu Asp Phe
                 320                 325                 330

 Leu Asn Ile Cys Ile Glu Pro Asp Thr Ile Ser Lys Gly Asp Phe
                 335                 340                 345

 Ile Thr Ile Gly Ser Arg Lys Val Arg Asn Pro Lys Leu His Val
                 350                 355                 360

 Glu Gly Thr Glu Cys Leu Gln Ala Ser Gln Cys Thr Leu Leu Ile
                 365                 370                 375

 Pro Glu Gly Ala Gly Gly Ser Phe Ser Ile Asp Ser Glu Glu Tyr
                 380                 385                 390

 Glu Ala Met Pro Val Glu Val Lys Leu Leu Pro Arg Lys Leu Gln
                 395                 400                 405

 Phe Phe Cys Asp Pro Arg Lys Arg Glu Gln Met Leu Thr Ser Pro
                 410                 415                 420

 Thr Gln


<210> 3243
<211> 4221
<212> DNA
<213> Homo sapien

<400> 3243
 cgataacgat ttgtgttgtg agaggcgcaa gctgcgattt ctgctgaact 50

 tggaggcatt tctacgactt ttctctcagc tgaggctttt cctccgaccc 100

 tgatgctctt caattcggtg ctccgccagc cccagcttgg cgtcctgaga 150

 aatggatggt cttcacaata ccctcttcaa tcccttctga ctggttatca 200

 gtgcagtggt aatgatgaac acacttctta tggagaaaca ggagtcccag 250

 ttcctccttt tggatgtacc ttctcttctg ctcccaatat ggaacatgta 300

 ctagcagttg ccaatgaaga aggctttgtt cgattgtata acacagaatc 350

 acaaagtttc agaaagaagt gcttcaaaga atggatggct cactggaatg 400

 ccgtctttga cctggcctgg gttcctggtg aacttaaact tgttacagca 450

 gcaggtgatc aaacagccaa attttgggac gtaaaagctg gtgagctgat 500

 tggaacatgc aaaggtcatc aatgcagcct caagtcagtt gccttttcta 550

 agtttgagaa agctgtattc tgtacgggtg gaagagatgg caacattatg 600

 gtctgggata ccaggtgcaa caaaaaagat gggttttata ggcaagtgaa 650

 tcaaatcagt ggagctcaca atacctcaga caagcaaacc ccttcaaaac 700

 ccaagaagaa acagaattca aaaggacttg ctccttctgt ggatttccag 750

 caaagtgtta ctgtggtcct ctttcaagac gagaatacct tagtctcagc 800

 aggagctgtg gatgggataa tcaaagtatg ggatttacgt aagaattata 850

 ctgcttatcg acaagaaccc atagcatcca agtctttcct gtacccaggt 900

 agcagcactc gaaaacttgg atattcaagt ctgattttgg attccactgg 950

 ctctacttta tttgctaatt gcacagacga taacatctac atgtttaata 1000

 tgactgggtt gaagacttct ccagtggcta ttttcaatgg acaccagaac 1050

 tctacctttt atgtaaaatc cagccttagt ccagatgacc agtttttagt 1100

 cagtggctca agtgatgaag ctgcctacat atggaaggtc tccacaccct 1150

 ggcaacctcc tactgtgctc ctgggtcatt ctcaagaggt cacgtctgtg 1200

 tgctggtgtc catctgactt cacaaagatt gctacctgtt ctgatgacaa 1250

 tacactaaaa atctggcgct tgaatagagg cttagaggag aaaccaggag 1300

 gtgataaact ttccacggtg ggttgggcct ctcagaagaa aaaagagtca 1350

 agacctggcc tagtaacagt aacgagtagc cagagtactc ctgccaaagc 1400

 ccccagggta aagtgcaatc catccaattc ttccccgtca tccgcagctt 1450

 gtgccccaag ctgtgctgga gacctccctc ttccttcaaa tactcctacg 1500

 ttctctatta aaacctctcc tgccaaggcc cggtctccca tcaacagaag 1550

 aggctctgtc tcctccgtct ctcccaagcc accttcatct ttcaagatgt 1600

 cgattagaaa ctgggtgacc cgaacacctt cctcatcacc acccatcact 1650

 ccacctgctt cggagaccaa gatcatgtct ccgagaaaag cccttattcc 1700

 tgtgagccag aagtcatccc aagcagaggc ttgctctgag tctagaaata 1750

 gagtaaagag gaggctagac tcaagctgtc tggagagtgt gaaacaaaag 1800

 tgtgtgaaga gttgtaactg tgtgactgag cttgatggcc aagttgaaaa 1850

 tcttcatttg gatctgtgct gccttgctgg taaccaggaa gaccttagta 1900

 aggactctct aggtcctacc aaatcaagca aaattgaagg agctggtacc 1950

 agtatctcag agcctccgtc tcctatcagt ccgtatgctt cagaaagctg 2000

 tggaacgcta cctcttcctt tgagaccttg tggagaaggg tctgaaatgg 2050

 taggcaaaga gaatagttcc ccagagaata aaaactggtt gttggccatg 2100

 gcagccaaac ggaaggctga gaatccatct ccacgaagtc cgtcatccca 2150

 gacacccaat tccaggagac agagcggaaa gacattgcca agcccggtca 2200

 ccatcacgcc cagctccatg aggaaaatct gcacatactt ccatagaaag 2250

 tcccaggagg acttctgtgg tcctgaacac tcaacagaat tatagattct 2300

 aatctgagtg agttactgag ctttggtcca ctaaaacaag ctgagctttg 2350

 gtccactaaa acaagatgaa aaatacaaga gtgactctat aactctggtc 2400

 tttaagaaag ctgccttttc atttttagac aaaatctttt caacgctgaa 2450

 atgtacctaa tctggttcta ctaccataat gtatatgcag cttcccgagg 2500

 atgaatgctg tgtttaaatt tcataaagta aatttgtcac tctagcattt 2550

 tgaatgaata gtcttcactt tttaaattat tcatcttctc tataataatg 2600

 acatcccagt tcatggaggc aaaaaacaag tttcttgtta tcctgaaact 2650

 ttctatgctc agtggaaagt atctgccagc cacagcatga ggcctgtgaa 2700

 ggctgactga gaaatcctct gctgaagacc cctggttctg ttctgcctcc 2750

 aacatgtata attttatttg aaatacataa tcttttcact atgcttttgt 2800

 ggggtttttt ttaagtatgt gtaaaaatgt gatgctcaga taagtacatt 2850

 tatatcagtt cagtgttaaa atgcagtctc ttgagttaaa gtcatcttta 2900

 ttttaaatgc agtgataaat gtcaactctt cggagaaact aggagaacaa 2950

 caacagaaag ctgtgtttgt cttttttctc tcaaatatat ctcccgtatg 3000

 agatttcagg tccccatgtt ttcaccaagc aatctgctat gtcagccaac 3050

 ccaacatcac tttctacagg aggttatgat ttttgccatt tactagagga 3100

 agatgtttta tgaaatcaat ttggggtttg aattcaggtg cagtcatcag 3150

 ttctttaggg gctgcaatgt tttaaaaaaa ataagtcatc agattttaag 3200

 aaaaaagtga tgatttctta ttgatatttt tgtaacagaa tatagctctt 3250

 aactgaaaat ccagaaccag aaacataaat cttgagtttc ttttcatgta 3300

 cataaaaagc aatagccttt tagtatagat agccctgagc caaaaagtaa 3350

 tagaattttc tctagatatt taatacagag agtgtataga ctgactctaa 3400

 gttaataatg tgcaaaatat cttaaacatc cctcccctta ttcaacaatt 3450

 atgtatcagt gatcttgaac cattgtttta tatttttcac ctttgtaacc 3500

 tcatggaaag aggctttaca tactttctat gtactattta cttagaaggg 3550

 agcccccttc cagtcatgaa acttcatttg ttttatccat atccctgagg 3600

 actgtgtaga ctttatgtca gttctgtgta gactttatgt cagtttttgt 3650

 cattatttga aaatctattc tgacaacttt ttaattcctt tgatcttata 3700

 agttaaagct gtaacaactg aaattgcatg gatcaagtaa gcatagtttt 3750

 atccagggag aaaaataaaa ggaagccata gaattgctct ggtcaaaacc 3800

 aagcacacca tagccttaac tgaatattta ggaaatctgc ctaatctgct 3850

 tatatttggt gtttgttttt tgactgttgg gctttgggaa gatgttattt 3900

 atgaccaata tctgccagta acgctgttta tctcacttgc tttgaaagcc 3950

 aatgggggaa aaaaatccat gaaaaaaaaa agattgataa agtagatgat 4000

 tttgtttgta tccctaccca tctcctggca gccctactga gtgaaattgg 4050

 gatacatttg gctgtcagaa attataccga gtctactggg tataacatgt 4100

 ctcacttgga aagctagtac ttttaaatgg gtgccaaagg tcaactgtaa 4150

 tgagataatt atccctgcct gtgtccatgt cagactttga gctgatcctg 4200

 aataataaag ccttttacct t 4221

<210> 3244
<211> 730
<212> PRT
<213> Homo sapien

<400> 3244
 Met Leu Phe Asn Ser Val Leu Arg Gln Pro Gln Leu Gly Val Leu
   1               5                  10                  15

 Arg Asn Gly Trp Ser Ser Gln Tyr Pro Leu Gln Ser Leu Leu Thr
                  20                  25                  30

 Gly Tyr Gln Cys Ser Gly Asn Asp Glu His Thr Ser Tyr Gly Glu
                  35                  40                  45

 Thr Gly Val Pro Val Pro Pro Phe Gly Cys Thr Phe Ser Ser Ala
                  50                  55                  60

 Pro Asn Met Glu His Val Leu Ala Val Ala Asn Glu Glu Gly Phe
                  65                  70                  75

 Val Arg Leu Tyr Asn Thr Glu Ser Gln Ser Phe Arg Lys Lys Cys
                  80                  85                  90

 Phe Lys Glu Trp Met Ala His Trp Asn Ala Val Phe Asp Leu Ala
                  95                 100                 105

 Trp Val Pro Gly Glu Leu Lys Leu Val Thr Ala Ala Gly Asp Gln
                 110                 115                 120

 Thr Ala Lys Phe Trp Asp Val Lys Ala Gly Glu Leu Ile Gly Thr
                 125                 130                 135

 Cys Lys Gly His Gln Cys Ser Leu Lys Ser Val Ala Phe Ser Lys
                 140                 145                 150

 Phe Glu Lys Ala Val Phe Cys Thr Gly Gly Arg Asp Gly Asn Ile
                 155                 160                 165

 Met Val Trp Asp Thr Arg Cys Asn Lys Lys Asp Gly Phe Tyr Arg
                 170                 175                 180

 Gln Val Asn Gln Ile Ser Gly Ala His Asn Thr Ser Asp Lys Gln
                 185                 190                 195

 Thr Pro Ser Lys Pro Lys Lys Lys Gln Asn Ser Lys Gly Leu Ala
                 200                 205                 210

 Pro Ser Val Asp Phe Gln Gln Ser Val Thr Val Val Leu Phe Gln
                 215                 220                 225

 Asp Glu Asn Thr Leu Val Ser Ala Gly Ala Val Asp Gly Ile Ile
                 230                 235                 240

 Lys Val Trp Asp Leu Arg Lys Asn Tyr Thr Ala Tyr Arg Gln Glu
                 245                 250                 255

 Pro Ile Ala Ser Lys Ser Phe Leu Tyr Pro Gly Ser Ser Thr Arg
                 260                 265                 270

 Lys Leu Gly Tyr Ser Ser Leu Ile Leu Asp Ser Thr Gly Ser Thr
                 275                 280                 285

 Leu Phe Ala Asn Cys Thr Asp Asp Asn Ile Tyr Met Phe Asn Met
                 290                 295                 300

 Thr Gly Leu Lys Thr Ser Pro Val Ala Ile Phe Asn Gly His Gln
                 305                 310                 315

 Asn Ser Thr Phe Tyr Val Lys Ser Ser Leu Ser Pro Asp Asp Gln
                 320                 325                 330

 Phe Leu Val Ser Gly Ser Ser Asp Glu Ala Ala Tyr Ile Trp Lys
                 335                 340                 345

 Val Ser Thr Pro Trp Gln Pro Pro Thr Val Leu Leu Gly His Ser
                 350                 355                 360

 Gln Glu Val Thr Ser Val Cys Trp Cys Pro Ser Asp Phe Thr Lys
                 365                 370                 375

 Ile Ala Thr Cys Ser Asp Asp Asn Thr Leu Lys Ile Trp Arg Leu
                 380                 385                 390

 Asn Arg Gly Leu Glu Glu Lys Pro Gly Gly Asp Lys Leu Ser Thr
                 395                 400                 405

 Val Gly Trp Ala Ser Gln Lys Lys Lys Glu Ser Arg Pro Gly Leu
                 410                 415                 420

 Val Thr Val Thr Ser Ser Gln Ser Thr Pro Ala Lys Ala Pro Arg
                 425                 430                 435

 Val Lys Cys Asn Pro Ser Asn Ser Ser Pro Ser Ser Ala Ala Cys
                 440                 445                 450

 Ala Pro Ser Cys Ala Gly Asp Leu Pro Leu Pro Ser Asn Thr Pro
                 455                 460                 465

 Thr Phe Ser Ile Lys Thr Ser Pro Ala Lys Ala Arg Ser Pro Ile
                 470                 475                 480

 Asn Arg Arg Gly Ser Val Ser Ser Val Ser Pro Lys Pro Pro Ser
                 485                 490                 495

 Ser Phe Lys Met Ser Ile Arg Asn Trp Val Thr Arg Thr Pro Ser
                 500                 505                 510

 Ser Ser Pro Pro Ile Thr Pro Pro Ala Ser Glu Thr Lys Ile Met
                 515                 520                 525

 Ser Pro Arg Lys Ala Leu Ile Pro Val Ser Gln Lys Ser Ser Gln
                 530                 535                 540

 Ala Glu Ala Cys Ser Glu Ser Arg Asn Arg Val Lys Arg Arg Leu
                 545                 550                 555

 Asp Ser Ser Cys Leu Glu Ser Val Lys Gln Lys Cys Val Lys Ser
                 560                 565                 570

 Cys Asn Cys Val Thr Glu Leu Asp Gly Gln Val Glu Asn Leu His
                 575                 580                 585

 Leu Asp Leu Cys Cys Leu Ala Gly Asn Gln Glu Asp Leu Ser Lys
                 590                 595                 600

 Asp Ser Leu Gly Pro Thr Lys Ser Ser Lys Ile Glu Gly Ala Gly
                 605                 610                 615

 Thr Ser Ile Ser Glu Pro Pro Ser Pro Ile Ser Pro Tyr Ala Ser
                 620                 625                 630

 Glu Ser Cys Gly Thr Leu Pro Leu Pro Leu Arg Pro Cys Gly Glu
                 635                 640                 645

 Gly Ser Glu Met Val Gly Lys Glu Asn Ser Ser Pro Glu Asn Lys
                 650                 655                 660

 Asn Trp Leu Leu Ala Met Ala Ala Lys Arg Lys Ala Glu Asn Pro
                 665                 670                 675

 Ser Pro Arg Ser Pro Ser Ser Gln Thr Pro Asn Ser Arg Arg Gln
                 680                 685                 690

 Ser Gly Lys Thr Leu Pro Ser Pro Val Thr Ile Thr Pro Ser Ser
                 695                 700                 705

 Met Arg Lys Ile Cys Thr Tyr Phe His Arg Lys Ser Gln Glu Asp
                 710                 715                 720

 Phe Cys Gly Pro Glu His Ser Thr Glu Leu
                 725                 730

<210> 3245
<211> 1118
<212> DNA
<213> Homo sapien

<400> 3245
 ctgatgaaag tgcttccaaa ctgaaaattg gacgtgcctt tacgatggta 50

 agcgttaaca gctcccactg cttctataat gactccttta agtacacttt 100

 gtatgggtgc atgttcagca tggtgtttgt gcttgggtta gtatccaatt 150

 gtgttgccat atacattttc atctgcgtcc tcaaagtccg aaatgaaact 200

 acaacttaca tgattaactt ggcaatgtca gacttgcttt ttgtttttac 250

 tttacccttc aggatttttt acttcacaac acggaattgg ccatttggag 300

 atttactttg taagatttct gtgatgctgt tttataccaa catgtacgga 350

 agcattctgt tcttaacctg tattagtgta gatcgatttc tggcaattgt 400

 ctacccattt aagtcaaaga ctctaagaac caaaagaaat gcaaagattg 450

 tttgcactgg cgtgtggtta actgtgatcg gaggaagtgc acccgccgtt 500

 tttgttcagt ctacccactc tcagggtaac aatgcctcag aagcctgctt 550

 tgaaaatttt ccagaagcca catggaaaac atatctctca aggattgtaa 600

 ttttcatcga aatagtggga ttttttattc ctctaatttt aaatgtaact 650

 tgttctagta tggtgctaaa aactttaacc aaaccagtta cattaagtag 700

 aagcaaaata aacaaaacta aggttttaaa aatgattttt gtacatttga 750

 tcatattctg tttctgtttt gttccttaca atatcaatct tattttatat 800

 tctcttgtga gaacacaaac atttgttaat tgctcagtag tggcagcagt 850

 aaggacaatg tacccaatca ctctctgtat tgctgtttcc aactgttgtt 900

 ttgaccctat agtttactac tttacatcgg acacaattca gaattcaata 950

 aaaatgaaaa actggtctgt caggagaagt gacttcagat tctctgaagt 1000

 tcatggtgca gagaatttta ttcagcataa cctacagacc ttaaaaagta 1050

 agatatttga caatgaatct gctgcctgaa ataaaaccat taggactcac 1100

 tgggacagaa ctttcaag 1118

<210> 3246
<211> 344
<212> PRT
<213> Homo sapien

<400> 3246
 Met Val Ser Val Asn Ser Ser His Cys Phe Tyr Asn Asp Ser Phe
   1               5                  10                  15

 Lys Tyr Thr Leu Tyr Gly Cys Met Phe Ser Met Val Phe Val Leu
                  20                  25                  30

 Gly Leu Val Ser Asn Cys Val Ala Ile Tyr Ile Phe Ile Cys Val
                  35                  40                  45

 Leu Lys Val Arg Asn Glu Thr Thr Thr Tyr Met Ile Asn Leu Ala
                  50                  55                  60

 Met Ser Asp Leu Leu Phe Val Phe Thr Leu Pro Phe Arg Ile Phe
                  65                  70                  75

 Tyr Phe Thr Thr Arg Asn Trp Pro Phe Gly Asp Leu Leu Cys Lys
                  80                  85                  90

 Ile Ser Val Met Leu Phe Tyr Thr Asn Met Tyr Gly Ser Ile Leu
                  95                 100                 105

 Phe Leu Thr Cys Ile Ser Val Asp Arg Phe Leu Ala Ile Val Tyr
                 110                 115                 120

 Pro Phe Lys Ser Lys Thr Leu Arg Thr Lys Arg Asn Ala Lys Ile
                 125                 130                 135

 Val Cys Thr Gly Val Trp Leu Thr Val Ile Gly Gly Ser Ala Pro
                 140                 145                 150

 Ala Val Phe Val Gln Ser Thr His Ser Gln Gly Asn Asn Ala Ser
                 155                 160                 165

 Glu Ala Cys Phe Glu Asn Phe Pro Glu Ala Thr Trp Lys Thr Tyr
                 170                 175                 180

 Leu Ser Arg Ile Val Ile Phe Ile Glu Ile Val Gly Phe Phe Ile
                 185                 190                 195

 Pro Leu Ile Leu Asn Val Thr Cys Ser Ser Met Val Leu Lys Thr
                 200                 205                 210

 Leu Thr Lys Pro Val Thr Leu Ser Arg Ser Lys Ile Asn Lys Thr
                 215                 220                 225

 Lys Val Leu Lys Met Ile Phe Val His Leu Ile Ile Phe Cys Phe
                 230                 235                 240

 Cys Phe Val Pro Tyr Asn Ile Asn Leu Ile Leu Tyr Ser Leu Val
                 245                 250                 255

 Arg Thr Gln Thr Phe Val Asn Cys Ser Val Val Ala Ala Val Arg
                 260                 265                 270

 Thr Met Tyr Pro Ile Thr Leu Cys Ile Ala Val Ser Asn Cys Cys
                 275                 280                 285

 Phe Asp Pro Ile Val Tyr Tyr Phe Thr Ser Asp Thr Ile Gln Asn
                 290                 295                 300

 Ser Ile Lys Met Lys Asn Trp Ser Val Arg Arg Ser Asp Phe Arg
                 305                 310                 315

 Phe Ser Glu Val His Gly Ala Glu Asn Phe Ile Gln His Asn Leu
                 320                 325                 330

 Gln Thr Leu Lys Ser Lys Ile Phe Asp Asn Glu Ser Ala Ala
                 335                 340

<210> 3247
<211> 1795
<212> DNA
<213> Homo sapien

<400> 3247
 cggcgacggc cggatggctg cgtggggctg tgtggctgcg ctcggcgcgg 50

 cgcgtgggct ttgctggcgg gcggcgcgcg cggctgcggg gctccagggc 100

 cgccccgccc gcaggtgcta tgctgtgggc cccgctcaga gcccacccac 150

 ctttgggttc ctgttggaca tcgatggagt gcttgtgcgg ggccacagag 200

 tgatccctgc tgctctgaaa gccttccgaa ggctggtgaa ctcccagggg 250

 cagctgcggg tgcccgtggt ttttgttaca aatgctggga acatcttaca 300

 acacagcaaa gcccaggagc tgtcagccct gctggggtgc gaggtggatg 350

 cagaccaagt tatcctctct cacagcccca tgaagctctt ctccgagtac 400

 catgagaagc ggatgctggt gtctggacag gggcccgtga tggaaaatgc 450

 ccagggactg ggcttccgaa atgtcgtcac cgtggatgag ctgcggatgg 500

 cctttcctct gcttgacatg gtggacctgg agcggcggct aaagaccacg 550

 cccctcccga ggaatgactt cccccgcatt gaaggggtgc tcctcctagg 600

 ggagccggtc cgctgggaga ccagcctgca gctgatcatg gatgtcctcc 650

 tcagcaatgg gagccctggg gctggcctgg caacaccccc ctacccccac 700

 ctccccgtcc tagccagcaa catggatctc ctgtggatgg ctgaagccaa 750

 gatgcccagg tttggacatg gcacctttct gctgtgcctg gaaaccattt 800

 accagaaagt gacgggcaag gagctgagat acgagggcct gatgggcaaa 850

 cccagcatcc tcacttacca gtatgccgag gacctgatca ggcgacaggc 900

 ggagaggcgg ggctgggccg cccccatccg gaagctctat gctgtgggtg 950

 ataaccctat gtctgacgta tacggcgcca acctgttcca ccagtacctg 1000

 cagaaggcaa cgcatgatgg ggcgccagaa ctaggggccg ggggcacacg 1050

 gcagcaacag ccctcagcaa gccagagctg catctccatc ctggtgtgta 1100

 caggcgtcta caatcccagg aacccacagt ccacggagcc tgtccttgga 1150

 ggaggggagc ctccattcca cgggcaccga gacttatgct tcagtccagg 1200

 gctcatggag gcctcccacg tggtgaatga cgtgaatgag gctgtgcagc 1250

 tggtcttccg caaggagggc tgggctttgg agtgagggca gtgcggtgga 1300

 ggtgaggggg tgagcctgga cctgtgggcg agtcccattg gctgggctct 1350

 ggcctgatca ctgggctcag gtcagggctt ggttcccttg ccacccttct 1400

 tgctgcccca tgagtgtggc attactggtc acttggaaga agacagtgac 1450

 tctttttccc tgctgggtag cattttgtat ggaacggttg gaattttctg 1500

 ggcccagttc ccacgtgcct ttcgtggcag tctaacctca ggccattctc 1550

 ttcccctgtg tgcctcagtg tccttctcat ttcagtaggg acttctgaaa 1600

 tgggggaggc agtgtggaat actgtggatg tctgtgcaga gcctttgccg 1650

 gcactgaagg catgcagcct gtcggcagag tgtcttaaca ccagatgcta 1700

 ctttttactg tattgtagtt tattgcccgg agatgtgggg cttttttttt 1750

 aaataaaata atcataataa atgttcatga tgctgactct tgtga 1795

<210> 3248
<211> 423
<212> PRT
<213> Homo sapien

<400> 3248
 Met Ala Ala Trp Gly Cys Val Ala Ala Leu Gly Ala Ala Arg Gly
   1               5                  10                  15

 Leu Cys Trp Arg Ala Ala Arg Ala Ala Ala Gly Leu Gln Gly Arg
                  20                  25                  30

 Pro Ala Arg Arg Cys Tyr Ala Val Gly Pro Ala Gln Ser Pro Pro
                  35                  40                  45

 Thr Phe Gly Phe Leu Leu Asp Ile Asp Gly Val Leu Val Arg Gly
                  50                  55                  60

 His Arg Val Ile Pro Ala Ala Leu Lys Ala Phe Arg Arg Leu Val
                  65                  70                  75

 Asn Ser Gln Gly Gln Leu Arg Val Pro Val Val Phe Val Thr Asn
                  80                  85                  90

 Ala Gly Asn Ile Leu Gln His Ser Lys Ala Gln Glu Leu Ser Ala
                  95                 100                 105

 Leu Leu Gly Cys Glu Val Asp Ala Asp Gln Val Ile Leu Ser His
                 110                 115                 120

 Ser Pro Met Lys Leu Phe Ser Glu Tyr His Glu Lys Arg Met Leu
                 125                 130                 135

 Val Ser Gly Gln Gly Pro Val Met Glu Asn Ala Gln Gly Leu Gly
                 140                 145                 150

 Phe Arg Asn Val Val Thr Val Asp Glu Leu Arg Met Ala Phe Pro
                 155                 160                 165

 Leu Leu Asp Met Val Asp Leu Glu Arg Arg Leu Lys Thr Thr Pro
                 170                 175                 180

 Leu Pro Arg Asn Asp Phe Pro Arg Ile Glu Gly Val Leu Leu Leu
                 185                 190                 195

 Gly Glu Pro Val Arg Trp Glu Thr Ser Leu Gln Leu Ile Met Asp
                 200                 205                 210

 Val Leu Leu Ser Asn Gly Ser Pro Gly Ala Gly Leu Ala Thr Pro
                 215                 220                 225

 Pro Tyr Pro His Leu Pro Val Leu Ala Ser Asn Met Asp Leu Leu
                 230                 235                 240

 Trp Met Ala Glu Ala Lys Met Pro Arg Phe Gly His Gly Thr Phe
                 245                 250                 255

 Leu Leu Cys Leu Glu Thr Ile Tyr Gln Lys Val Thr Gly Lys Glu
                 260                 265                 270

 Leu Arg Tyr Glu Gly Leu Met Gly Lys Pro Ser Ile Leu Thr Tyr
                 275                 280                 285

 Gln Tyr Ala Glu Asp Leu Ile Arg Arg Gln Ala Glu Arg Arg Gly
                 290                 295                 300

 Trp Ala Ala Pro Ile Arg Lys Leu Tyr Ala Val Gly Asp Asn Pro
                 305                 310                 315

 Met Ser Asp Val Tyr Gly Ala Asn Leu Phe His Gln Tyr Leu Gln
                 320                 325                 330

 Lys Ala Thr His Asp Gly Ala Pro Glu Leu Gly Ala Gly Gly Thr
                 335                 340                 345

 Arg Gln Gln Gln Pro Ser Ala Ser Gln Ser Cys Ile Ser Ile Leu
                 350                 355                 360

 Val Cys Thr Gly Val Tyr Asn Pro Arg Asn Pro Gln Ser Thr Glu
                 365                 370                 375

 Pro Val Leu Gly Gly Gly Glu Pro Pro Phe His Gly His Arg Asp
                 380                 385                 390

 Leu Cys Phe Ser Pro Gly Leu Met Glu Ala Ser His Val Val Asn
                 395                 400                 405

 Asp Val Asn Glu Ala Val Gln Leu Val Phe Arg Lys Glu Gly Trp
                 410                 415                 420

 Ala Leu Glu


<210> 3249
<211> 636
<212> DNA
<213> Homo sapien

<400> 3249
 gatcgcggag tcggtgcttt agtacgccgc tggcaccttt actctcgccg 50

 gccgcgcgaa cccgtttgag ctcggtatcc tagtgcacac gcctttgcaa 100

 gcgacggcgc catgagtctg acttccagtt ccagcgtacg agttgaatgg 150

 atcgcagcag ttaccattgc tgctgggaca gctgcaattg gttatctagc 200

 ttacaaaaga ttttatgtta aagatcatcg aaataaagct atgataaacc 250

 ttcacatcca gaaagacaac cccaagatag tacatgcttt tgacatggag 300

 gatttgggag ataaagctgt gtactgccgt tgttggaggt ccaaaaagtt 350

 cccattctgt gatggggctc acacaaaaca taacgaagag actggagaca 400

 atgtgggccc tctgatcatc aagaaaaaag aaacttaaat ggacactttt 450

 gatgctgcaa atcagcttgt cgtgaagtta cctgattgtt taattagaat 500

 gactaccacc tctgtctgat tcaccttcgc tggattctaa atgtggtata 550

 ttgcaaactg cagctttcac atttatggca tttgtcttgt tgaaacatcg 600

 tggtgcacat ttgtttaaac aaaaaaaaaa aaaaaa 636

<210> 3250
<211> 108
<212> PRT
<213> Homo sapien

<400> 3250
 Met Ser Leu Thr Ser Ser Ser Ser Val Arg Val Glu Trp Ile Ala
   1               5                  10                  15

 Ala Val Thr Ile Ala Ala Gly Thr Ala Ala Ile Gly Tyr Leu Ala
                  20                  25                  30

 Tyr Lys Arg Phe Tyr Val Lys Asp His Arg Asn Lys Ala Met Ile
                  35                  40                  45

 Asn Leu His Ile Gln Lys Asp Asn Pro Lys Ile Val His Ala Phe
                  50                  55                  60

 Asp Met Glu Asp Leu Gly Asp Lys Ala Val Tyr Cys Arg Cys Trp
                  65                  70                  75

 Arg Ser Lys Lys Phe Pro Phe Cys Asp Gly Ala His Thr Lys His
                  80                  85                  90

 Asn Glu Glu Thr Gly Asp Asn Val Gly Pro Leu Ile Ile Lys Lys
                  95                 100                 105

 Lys Glu Thr


<210> 3251
<211> 5634
<212> DNA
<213> Homo sapien

<400> 3251
 gccttttccc tccggctcgg gagcgtctcg cttgcgcccc gggcccgcgg 50

 cgcccgcgcg gctgcgagcc tcgggtggcc gcgtgccggc tccaggaagc 100

 cggagagggc gcggcggcca ggatggcgcg gcacgggccg tgcggctaga 150

 cgggagccga gggaaccgcc ggctcgcgcc ctccgttctt tcccggagcc 200

 ggcttcacgc agggccggga acggccgtgc ctctgggatc cgccttcgct 250

 gacgccgggc acctacctgg acgcgagcga gcgagatgcc caaccccaaa 300

 aacagcaaag gcggccgcaa aaacaagcgc gccaacagca gcggcgacga 350

 gcaggaaaat ggagccgggg ccctggcagc ggcgggcgcg gcgggagcgg 400

 cggccggggg ggccctggcg gcggcggccg gttgcggggc ggcggcggcg 450

 ggcgcgccgg gcgccggagg cgcggcgggc gccggaggcg cggggactgg 500

 cgccgcgaac gctgcggccg ccgcgggggc tgcggccgcg ggcgatgcca 550

 aaaacgaagc cccatgtgcc actcccctga tctgcagctt cggtaggccg 600

 gtggacctgg agaaggacga ctaccagaag gtggtgtgca acaacgagca 650

 ctgcccctgc agcacctgga tgcacctgca gtgcttctac gagtgggaga 700

 gcagcatcct cgtccagttc aactgcatcg gccgcgcgcg cagctggaac 750

 gagaagcaat gccgccagaa catgtggaca aagaagggct acgacctggc 800

 cttccgcttc tgctcttgcc gctgtggcca gggccacttg aagaaggaca 850

 cagactggta tcaggtgaag cggatgcagg acgagaaaaa gaagaagtct 900

 ggctccgaga agaacacagg gaggcctcct ggtgaggcgg cggaggaggc 950

 aaaaaagtgc aggcccccaa ataagcccca gaaaggccca agccacgacc 1000

 tcccccgccg gcattccatg gaccggcaga actcccagga gaaggcagtg 1050

 ggtgccgcag cctacggtgc ccgttccccc ggtggctccc cgggccagtc 1100

 cccacccacg ggctactcca tcctctctcc tgcccacttc agcggccccc 1150

 gctcctccag atacctcggg gagttcttaa agaacgccat ccatctggag 1200

 cctcacaaga aggccatggc tgggggccat gtgttcagaa atgcccactt 1250

 tgattacagc cctgcggggt tggcagttca caggggggga cacttcgaca 1300

 cccccgtgca gttccttcgg cggctggacc tctccgaact cctcactcac 1350

 atccccaggc ataagctgaa cactttccac gtgcgcatgg aagacgatgc 1400

 ccaagtgggc cagggggaag acttgcggaa gttcattctg gccgcgctca 1450

 gtgccagcca cagaaacgtg gtaaactgtg ccctgtgcca ccgggcgctc 1500

 ccggtgttcg aacagttccc actggtggat ggaactttgt tcctaagccc 1550

 gtcgagacat gatgagatcg aatatgatgt tccttgtcac cttcaaggga 1600

 gactcatgca tctgtatgcc gtgtgcgtgg actgcctgga aggggttcac 1650

 aagatcatct gcatcaagtg taagtcacgg tgggatggca gctggcacca 1700

 gctgggcact atgtacacct acgacatcct ggctgcctct ccatgttgtc 1750

 aggcccgcct gaactgtaag cactgtggga agccggtgat cgacgtgagg 1800

 atcgggatgc agtacttctc cgaatatagc aacgtccagc agtgtccaca 1850

 ctgtgggaac ctggactacc acttcgtgaa gccattttcc tccttcaaag 1900

 ttctcgaagc ttattgatga aagctttgct ttagtaatag ctattttatt 1950

 gatattatta ctttattaca tatcttttat agggaaacat tctgtgacat 2000

 taatttcctt tctaatttaa aggagagtta ctttgttgta tgtgtgccac 2050

 taaaataggg gctgcccttg ccctgtcttg attcccgagt gttaatctgt 2100

 ggttttgacc agagcccaga tgggtaatcc tgtgcatttg ggttggggtt 2150

 cactcttacc aagaatcttt gatgcagctt taagatggtg gggaggatgg 2200

 ggtgaattta ggaaaggaat ttgtggttat aaactaagag cttgatagga 2250

 gttggaagga aactcttact aaaatgttaa ctttctaaaa accttctttt 2300

 agatcttcct tgggcctttg gaaaaatatg tgacaagtga atgtaagtct 2350

 gtgcctggag agctaatagt gcattagtct atctcagcct agtgttctgc 2400

 agcacacatg ggcaggcagt ttactcacac tgacaggtga cctgaaagtg 2450

 gcacaagtgc tgtttctatc actattgtaa tttgccagtt catttttcat 2500

 gctgaaagta atatccaaat tgtaagacat atgaaagata ttagtgttgc 2550

 aaatatgttt aggtaaactg acctataaca gaatatgtga aatgaatttg 2600

 gaaataatgc aagaaggcag aactcaatca tttaaattgt gtctttgaag 2650

 ttggtaatat agcttttaag gagaacccat gaataacctg atttgggcag 2700

 tgatgattta ttacaggttg cactgttgaa gtgtcatttg gtgtcaggtt 2750

 cttctcacag gtaaatcttt cagccacaga atctaactgg tgagcttcag 2800

 aaccaataat tgccacattt attgtcctca aaattgctta tggccatgtt 2850

 taaccaatta attctgagtt tccaaaatca aagatttgac cttaagaggg 2900

 aagggaaaaa agtgtgaaag gatgatgaag aaaataattt tactatttct 2950

 tttaaaagta tgttttggaa aatcaatgat tttaatgcat agcagtatgt 3000

 ttgaaaaata gaccattcta aaaagcccat gataccttac tgttgatgaa 3050

 aaaggatgat catatatata gaacttgatt agtcagagca ttgggcattc 3100

 caaaatacag cctttggttc agtagatttt aatgctttaa atagactgac 3150

 gtcgcatacc cttatagaat tggaatatga tttctcaaaa attaatttga 3200

 taatttcatg tatgatgtgc atatatgcta aaagaatgca gaaaatcatt 3250

 ttatgaatag ccaaatttgg ggttgatgtg aacattttat gttactcatt 3300

 tggtttatac tttttttttt ttttttttaa ctgtgtggtt tttcttttca 3350

 gaagtattta ggcaatattg cacgtgagtt tcagttcttt ttttcttttt 3400

 tttgagatgg agtctcactc ttgtcaccca ggctggagtg cagtagtgcg 3450

 atctcagctc actgcaacct ctgcctcctg gattcaagcg attctcctgt 3500

 cccagcctcc caggtagctg ggactatagg cacgtgccac cacacccggc 3550

 taattttttg tatttttagt agagacagcg tttcaccatg ttagctagga 3600

 tggtctagat ctcctgacct tgtgatctgc ctgcctcggc ctcccaaagt 3650

 gctgggatta caggcgtgag tcactgcgcc tggccaagtt tcagttctat 3700

 atgaagtatt tgatgttttg tttgaaacaa tacagcatta aagaaccaat 3750

 gttattcact aatatcattc atctttcagt ttggatgatt tggtttgctg 3800

 catctaggtc ggtgtttgat catctgaaaa aacatttcag tgggaagaaa 3850

 tgcataaaat gcctataaga agtagaaagt cattgaactg acagtgtttg 3900

 atgcaactaa aagaggattg taagcatagc tttctgcaaa cttgtcttta 3950

 atgcacaaag ctgtagtggt gaattaacta tctccttatt gattctctcc 4000

 tgtacccaga tgcaaaaagt gctaagtttc tcttgtcctc gtaataccat 4050

 ttggatttta tttctgaatt taaatagtaa aatatttatg atgctgatct 4100

 ttaacccacc taaaatttta tagtgaaacc tgctttatat tgttgttctg 4150

 aagcttacaa ttgacctata cattgcattc agcaagctcc tgaatttaga 4200

 actgccgtca gtgtagtgta tgctgtgttc catgttgcct ttttagatgg 4250

 ctttctaccc cctgaacaat aaataggatg aggttttact gtaattgggt 4300

 aaagtttact cttggacatt atttcgatgc taaagtaagg attctgtgga 4350

 tgttacttaa agagaaaagc ataagagcat gaagcatatc tgggaatatc 4400

 ttttgccttt aagacgattc attcttgtct agagggaaaa tctggctgat 4450

 ttgggaataa aatataatcg aatattcaac accatgaaga taaatcttat 4500

 tttggaaatc tactgacctt aataccccaa gcttgccctg aatactttga 4550

 ttggaattgg aatatatcaa aaaaggttag tatttttgtt gtagttagga 4600

 tactaaaagg atattagtta cccaagagat ccaatttgtt tttctgatga 4650

 atagtgttca gtaaaatgaa gcagtcttaa gagtgactaa taatttcaaa 4700

 gtgatttttc gtctattctt aatatttttt aattatttat ttttaagagt 4750

 tttatacctt gagcagatac aatgatctgc tttagtgaga ggacaatttc 4800

 tgattgattg ttttctcttc aggccatctc acctcttcat tctcttgtta 4850

 catttgaagc agttgatata atgggtttat actttaaaag atagacatgg 4900

 tgccatgaag ttggggagtt gggtgaatta tcccattcta gttacagagg 4950

 agctttcctt aaatgccctt taacttctag gttttgttca agaagttcat 5000

 tttctgagta aaagttattt tcatatatgt tgggggaaaa ttaactcatc 5050

 taaaaagaat cttattaggt atttgaactc taaaactaac agataagaca 5100

 gatatgtacc ttattagagc accagaacta atttgctaag tcttttgttt 5150

 agtcctgcaa gactgatgct taatacacag tctgttctcc tgtgtctagg 5200

 tcaggaactc cagtttgctt ttctgttttg tgtcctggta gcagctgttg 5250

 agtaactttc attggaggtt gggaaggaag tgaggagaaa gtgttcttgt 5300

 ttagtgtttt atttcctata ataggatgct gcctaaccca gttcatctct 5350

 atgtcctgtt cactgaatat tccgggtaat tgaaagaaaa tataatggat 5400

 gggctccatt aaaaccagct caaaaataaa ttcttgtcag taaagatttc 5450

 ttgtcaagat gtcttggatt gcacttttgt tgaggaaaga cagtgtaaat 5500

 agttaaagaa tgttgataaa attgaaacat ttggttgtgg aattgtgtgt 5550

 ggttttagag ggtttctgtt tgtgaaatgt atgtattaaa aataataaaa 5600

 ttccagaaac taaaaaaaaa aaaaaaaaaa aaaa 5634

<210> 3252
<211> 543
<212> PRT
<213> Homo sapien

<400> 3252
 Met Pro Asn Pro Lys Asn Ser Lys Gly Gly Arg Lys Asn Lys Arg
   1               5                  10                  15

 Ala Asn Ser Ser Gly Asp Glu Gln Glu Asn Gly Ala Gly Ala Leu
                  20                  25                  30

 Ala Ala Ala Gly Ala Ala Gly Ala Ala Ala Gly Gly Ala Leu Ala
                  35                  40                  45

 Ala Ala Ala Gly Cys Gly Ala Ala Ala Ala Gly Ala Pro Gly Ala
                  50                  55                  60

 Gly Gly Ala Ala Gly Ala Gly Gly Ala Gly Thr Gly Ala Ala Asn
                  65                  70                  75

 Ala Ala Ala Ala Ala Gly Ala Ala Ala Ala Gly Asp Ala Lys Asn
                  80                  85                  90

 Glu Ala Pro Cys Ala Thr Pro Leu Ile Cys Ser Phe Gly Arg Pro
                  95                 100                 105

 Val Asp Leu Glu Lys Asp Asp Tyr Gln Lys Val Val Cys Asn Asn
                 110                 115                 120

 Glu His Cys Pro Cys Ser Thr Trp Met His Leu Gln Cys Phe Tyr
                 125                 130                 135

 Glu Trp Glu Ser Ser Ile Leu Val Gln Phe Asn Cys Ile Gly Arg
                 140                 145                 150

 Ala Arg Ser Trp Asn Glu Lys Gln Cys Arg Gln Asn Met Trp Thr
                 155                 160                 165

 Lys Lys Gly Tyr Asp Leu Ala Phe Arg Phe Cys Ser Cys Arg Cys
                 170                 175                 180

 Gly Gln Gly His Leu Lys Lys Asp Thr Asp Trp Tyr Gln Val Lys
                 185                 190                 195

 Arg Met Gln Asp Glu Lys Lys Lys Lys Ser Gly Ser Glu Lys Asn
                 200                 205                 210

 Thr Gly Arg Pro Pro Gly Glu Ala Ala Glu Glu Ala Lys Lys Cys
                 215                 220                 225

 Arg Pro Pro Asn Lys Pro Gln Lys Gly Pro Ser His Asp Leu Pro
                 230                 235                 240

 Arg Arg His Ser Met Asp Arg Gln Asn Ser Gln Glu Lys Ala Val
                 245                 250                 255

 Gly Ala Ala Ala Tyr Gly Ala Arg Ser Pro Gly Gly Ser Pro Gly
                 260                 265                 270

 Gln Ser Pro Pro Thr Gly Tyr Ser Ile Leu Ser Pro Ala His Phe
                 275                 280                 285

 Ser Gly Pro Arg Ser Ser Arg Tyr Leu Gly Glu Phe Leu Lys Asn
                 290                 295                 300

 Ala Ile His Leu Glu Pro His Lys Lys Ala Met Ala Gly Gly His
                 305                 310                 315

 Val Phe Arg Asn Ala His Phe Asp Tyr Ser Pro Ala Gly Leu Ala
                 320                 325                 330

 Val His Arg Gly Gly His Phe Asp Thr Pro Val Gln Phe Leu Arg
                 335                 340                 345

 Arg Leu Asp Leu Ser Glu Leu Leu Thr His Ile Pro Arg His Lys
                 350                 355                 360

 Leu Asn Thr Phe His Val Arg Met Glu Asp Asp Ala Gln Val Gly
                 365                 370                 375

 Gln Gly Glu Asp Leu Arg Lys Phe Ile Leu Ala Ala Leu Ser Ala
                 380                 385                 390

 Ser His Arg Asn Val Val Asn Cys Ala Leu Cys His Arg Ala Leu
                 395                 400                 405

 Pro Val Phe Glu Gln Phe Pro Leu Val Asp Gly Thr Leu Phe Leu
                 410                 415                 420

 Ser Pro Ser Arg His Asp Glu Ile Glu Tyr Asp Val Pro Cys His
                 425                 430                 435

 Leu Gln Gly Arg Leu Met His Leu Tyr Ala Val Cys Val Asp Cys
                 440                 445                 450

 Leu Glu Gly Val His Lys Ile Ile Cys Ile Lys Cys Lys Ser Arg
                 455                 460                 465

 Trp Asp Gly Ser Trp His Gln Leu Gly Thr Met Tyr Thr Tyr Asp
                 470                 475                 480

 Ile Leu Ala Ala Ser Pro Cys Cys Gln Ala Arg Leu Asn Cys Lys
                 485                 490                 495

 His Cys Gly Lys Pro Val Ile Asp Val Arg Ile Gly Met Gln Tyr
                 500                 505                 510

 Phe Ser Glu Tyr Ser Asn Val Gln Gln Cys Pro His Cys Gly Asn
                 515                 520                 525

 Leu Asp Tyr His Phe Val Lys Pro Phe Ser Ser Phe Lys Val Leu
                 530                 535                 540

 Glu Ala Tyr


<210> 3253
<211> 6894
<212> DNA
<213> Homo sapien

<400> 3253
 tgacccggtc cgtgtgggcc agcgggaagg aagccagttg agggaagttc 50

 tccatgaatg tacgtcacaa tgatgatgac cgaccaaatc cctctggaac 100

 tgccaccatt gctgaacgga gaggtagcca tgatgcccca cttggtgaat 150

 ggagatgcag ctcagcaggt tattctcgtt caagttaatc caggtgagac 200

 tttcacaata agagcagagg atggaacact tcagtgcatt caaggacctg 250

 ctgaagttcc catgatgtca cccaatggat ccattcctcc cattcatgtg 300

 cctccaggtt atatctcaca ggtgattgaa gatagtactg gagtccgccg 350

 ggtggtggtc acaccccagt ctcctgagtg ttatccccca agctacccct 400

 cagccatgtc tccaacccat catctccctc cctatctgac tcaccatcca 450

 cattttattc ataactcaca cacggcttac tacccacctg ttaccggacc 500

 tggagatatg ccgcctcagt tttttcccca gcatcatctt ccccacacaa 550

 tatatggtga gcaagaaatt ataccatttt atggaatgtc aagctacatc 600

 acccgagaag accagtacag caagcctccg cacaaaaaac tgaaagaccg 650

 ccagatcgat cgccagaacc gactcaacag acctccttct gctatctaca 700

 aaagcagctg cacaacagta tacaatggct atgggaaggg ccatagtggt 750

 ggaagtggcg gaggcggcag cggtagtggt cccggaatta agaaaacaga 800

 gcgacgagca agaagcagcc caaagtcgaa tgattcagac ttgcaagaat 850

 atgagttgga agtaaagagg gtgcaagaca ttctttcggg aatagagaaa 900

 ccacaggttt ctaatattca ggcaagagca gttgtgttgt cctgggctcc 950

 ccctgttgga ctttcctgtg gaccccacag tggtctttcc ttcccctaca 1000

 gttacgaggt ggccttatca gacaaaggac gagatggaaa atacaagata 1050

 atttacagtg gagaagaatt agaatgtaac ctgaaagatc ttagaccagc 1100

 aacagattat catgtgaggg tgtatgccat gtacaattcc gtaaagggat 1150

 cctgctccga gcctgttagc ttcaccaccc acagctgtgc acccgagtgt 1200

 cctttccccc ctaagctggc acataggagc aaaagttcac taaccctgca 1250

 gtggaaggca ccaattgaca acggttcaaa aatcaccaac taccttttag 1300

 agtgggatga gggaaaaaga aatagtggtt tcagacagtg cttcttcggg 1350

 agccagaagc actgcaagtt gacaaagctt tgtccggcaa tggggtacac 1400

 attcaggctg gccgctcgaa acgacattgg taccagtggt tatagccaag 1450

 aggtggtgtg ctacacatta ggaaatatcc ctcagatgcc ttctgcacca 1500

 aggctggttc gagctggcat cacatgggtc acgttgcagt ggagtaagcc 1550

 agaaggctgt tcacccgagg aagtgatcac ctacaccttg gaaattcagg 1600

 aggatgaaaa tgataacctt ttccacccaa aatacactgg agaggattta 1650

 acctgtactg tgaaaaatct caaaagaagc acacagtata cattcaggct 1700

 gactgcttct aatacggaag gaaaaagctg tccaagcgaa gttcttgttt 1750

 gtacgacgag tcctgacagg cctggacctc ctaccagacc gcttgtcaaa 1800

 ggcccagtta catctcatgg ctttagtgtc aaatgggatc cccctaagga 1850

 caatggtggt tcagaaatcc tcaagtactt gctagagatt actgatggaa 1900

 attctgaagc gaatcagtgg gaagtggcct acagtgggtc ggctaccgaa 1950

 tacaccttca cccacttgaa accaggcact ttgtacaaac tccgagcatg 2000

 ctgcatcagt accggcggac acagccagtg ttctgaaagt ctccctgttc 2050

 gcacactaag cattgcacca ggtcaatgtc gaccaccgag ggttttgggt 2100

 agaccaaagc acaaagaagt ccacttagag tgggatgttc ctgcatcgga 2150

 aagtggctgt gaggtctcag agtacagcgt ggagatgacg gagcccgaag 2200

 acgtagcctc ggaagtgtac catggcccag agctggagtg caccgtcggc 2250

 aacctgcttc ctggaaccgt gtatcgcttc cgggtgaggg ctctgaatga 2300

 tggagggtat ggtccctatt ctgatgtctc agaaattacc actgctgcag 2350

 ggcctcctgg acaatgcaaa gcaccttgta tttcttgtac acctgatgga 2400

 tgtgtcttag tgggttggga gagtcctgat agttctggtg ctgacatctc 2450

 agagtacagg ttggaatggg gagaagatga agaatcctta gaactcattt 2500

 atcatgggac agacacccgt tttgaaataa gagacctgtt gcctgctgca 2550

 cagtattgct gtagactaca ggccttcaat caagcagggg cagggccgta 2600

 cagtgaactt gtcctttgcc agacgccagc gtctgcccct gaccccgtct 2650

 ccactctctg tgtcctggag gaggagcccc ttgatgccta ccctgattca 2700

 ccttctgcgt gccttgtact gaactgggaa gagccgtgca ataacggatc 2750

 tgaaatcctt gcttacacca ttgatctagg agacactagc attaccgtgg 2800

 gcaacaccac catgcatgtt atgaaagatc tccttccaga aaccacctac 2850

 cggatcagaa ttcaggctat aaatgaaatt ggagctggac catttagtca 2900

 gttcattaaa gcaaaaactc ggccattacc acccttgcct cctaggctag 2950

 aatgtgctgc tgctggtcct cagagcctga agctaaaatg gggagacagt 3000

 aactccaaga cacatgctgc tgaggacatt gtgtacacac tacagctgga 3050

 ggacagaaac aagaggttta tttcaatcta cagaggaccc agccacacct 3100

 acaaggtcca gagactgacg gaattcacat gctactcctt cagaatccag 3150

 gcagcaagcg aggctggaga agggcccttc tcagaaacct ataccttcag 3200

 cacaaccaaa agtgtccccc ccaccatcaa agcacctcga gtaacacagt 3250

 tagaaggaaa ttcatgtgaa attttatggg agacggtacc atcaatgaaa 3300

 ggtgaccctg ttaactacat tctgcaggta ttggttggaa gagaatctga 3350

 gtacaaacag gtgtacaagg gagaagaagc cacattccaa atctcaggcc 3400

 tccagaccaa cacagactac aggttccgcg tatgtgcgtg tcgtcgctgt 3450

 ttagacacct ctcaggagct aagcggagcc ttcagcccct ctgcggcttt 3500

 tgtattacaa cgaagtgagg tcatgcttac aggggacatg gggagcttag 3550

 atgatcccaa aatgaagagc atgatgccta ctgatgaaca gtttgcagcc 3600

 atcattgtgc ttggctttgc aactttgtcc attttatttg cctttatatt 3650

 acagtacttc ttaatgaagt aaacccaaca aaactagagg tatgaattaa 3700

 tgctacacat tttaatacac acatttattc agatactccc ctttttaaag 3750

 cccttttgtt ttttgattta tatactctgt tttacagatt tagctagaaa 3800

 aaaaatgtca gtgttttggt gcaccttttt gaaatgcaaa actaggaaaa 3850

 ggttaaactg gatttttttt tttaaaaaaa agaaaaaaaa agaagaaaag 3900

 tataccagat accaaaagct agctttctta tgttttcctt taaattttca 3950

 gatttacctt cattctgttt tcactgatgt cttttgcaag cctttgattt 4000

 tttttttttt gttacagttt agtaatttat attcaccagt cacttcatat 4050

 gtcttgaaca tctgtatctg taaacatgaa tcaccgtgtg tgtacttaca 4100

 gggctaggat ttcagtgttg tcagagtatt accacacagc aacagcaaca 4150

 tacagaagat atgttcactc agataagact gccctaaaca accattttgt 4200

 cactcagtta tttaactgtg tttagctcat ttaaatcaaa atgtgtactt 4250

 taatctaaaa tgttttaata atctgtattt cttataattt taacactatg 4300

 agctgcctgt ataagaaatc aagtaaccag aatgcaccta taaattatgg 4350

 agcattgtag attttaccac atcaattcat agcagtaact ttaagagggc 4400

 attgtgcaat agttagttgt tttcttgttc agctatttta aaggctgctt 4450

 taacttgttt gtttgtcttt gtatataact acttctaatc taatcactag 4500

 agttattata ttctgttatg tttgaccaga attatatgac aagaactggt 4550

 gacagtttag tgcctctgcc cattgtccat gatttacact aattgtgagc 4600

 agtcttctta tgtgtcagct cattattttt gaaacatttg cctttaggct 4650

 gttctttgag gtatcaatga agtgattgaa tttcaatacc ttaattcagt 4700

 gcacataata ctaatgtaac agcagatgaa aattgataaa acccaaaaga 4750

 gagtcatcta aatttgtagt tcctatttct gtgggtttgc ctggccatgg 4800

 ttggagaggg aatggtgttt gatggtaaac acagggtgtt tggggatcaa 4850

 ggagcctaga ttctctccct ggatctgtca ctaacttgct gcgtgacctg 4900

 aacacgtcac tttacctctc tgtgcctcag ttttcccatg catgaaaaat 4950

 aaaataaaat aaaacgggga ttctaatgtt tgtaagtgct ttgagatctt 5000

 tgaccaacag gtgctattgg agtgcaaagt gttactctta cgtgtttatt 5050

 ttgagtcatg agataatcaa ttttaaccca aagtcattgg attatttata 5100

 tgaagtccat aatgttcgag tacctcaggg acatttaaga gttggaggtg 5150

 caaatatatt ccaaaagggt gcaacagaca cagtgtatcc ccctgcttct 5200

 gtttttgtat atttttgcta cttggttttt cttgatcata gctattttgt 5250

 gcttgatctt tattgtctaa gatgcagtat cctgtactag cttataatat 5300

 tcccatacca aagtcatggg gaaacaaaca ttattttgtt tttggtttat 5350

 ttatactata ttctgcatac agtactttaa atgccaatta cagtgcaatc 5400

 tttatttatt gtaaaatttt ttaagtgtac ttatgtacta attttccctt 5450

 gtagcatgtt atatttttgt gttttatact tttgtaattt taggtcagtc 5500

 ttgttccttg gcaacatctg tagtattatt aatcttctga cattttctta 5550

 tgtttttaaa aagataagag catctagtgc attaaatgcc aaaaaaaaaa 5600

 tacattatca gtgattgaaa cgtttacatg tacccaaaaa ccataatcat 5650

 ctcttggaag aaaatgctga gatcaatgaa ttattctgtg tgcctatatt 5700

 gacgtagtga gtactagaga gttctgtatt ttattattga ctataataat 5750

 tagtttaatt agctttgcaa actgatggca tcaaggtaaa tatatttttg 5800

 ccaaagttct ggccttccaa aactcacccc cttatttaaa tgtgtgctat 5850

 gacccactat gaccacagca tctgcatttt ctaaaaaatt ccatgcaggt 5900

 gttttgggga gaggtatttt ttaagcaatg aaaattcaac tgagtacaaa 5950

 gccccctctt ggggggttgg ggaagtctct tttttgaaac acttcagaac 6000

 tgctgctata aagaaattct ctaattggtt gaattttttt tttaagtaaa 6050

 tagtacttta ggccaaaatt tatatgaata tttgatcttc ttgagatttt 6100

 catactatca tttaaccacc aggaagctga agtgtgtgaa gtacaaagct 6150

 gacagcactt tattttattg ctctccatta tttggtattc attatattcc 6200

 ttcagtcaga aaattattac tctctatggc actgtttttt atcacaaata 6250

 tgtatatgtg atattgatat ataactatat atattgccat cacacacgaa 6300

 caataaaata aagtgttcta ttaacctgat ctctttgccc ttttgctatg 6350

 tgaggagtga atgagtggcc ttctgatgct ctgactcttc tctgtatgtc 6400

 aaactcatcc ctggcacaag aaattccagt catgtgaagc aaactgccct 6450

 ttgtcctcaa agaaattgtt gaaaaagaaa actttttaaa gagatttttt 6500

 gcatattctc tgccttgttc ttatcaactt gaaatgttgg cattttctaa 6550

 ccttgttttg ttggctacaa taattcagta ttcatgtcaa aattgagaag 6600

 tgccctaatt gaatgtgttt gaatgttatc cttgcacaat tctttaaatt 6650

 gaaagataaa atgttttacc tcactgttgg acatacattc caagcttttc 6700

 aactctagga gaaaaagaaa atcatgtttt cctgtattgt aaattttaga 6750

 ctatttcata tacattgtat taaaactgcc atatcaattt taatgtatag 6800

 attttgcaaa tattatgcta tatgtaatac ctaactgtat ctgtagtgta 6850

 tatgtaatat atttatgccc aataaatgtt ttaattcttt ctga 6894

<210> 3254
<211> 1204
<212> PRT
<213> Homo sapien

<400> 3254
 Met Tyr Val Thr Met Met Met Thr Asp Gln Ile Pro Leu Glu Leu
   1               5                  10                  15

 Pro Pro Leu Leu Asn Gly Glu Val Ala Met Met Pro His Leu Val
                  20                  25                  30

 Asn Gly Asp Ala Ala Gln Gln Val Ile Leu Val Gln Val Asn Pro
                  35                  40                  45

 Gly Glu Thr Phe Thr Ile Arg Ala Glu Asp Gly Thr Leu Gln Cys
                  50                  55                  60

 Ile Gln Gly Pro Ala Glu Val Pro Met Met Ser Pro Asn Gly Ser
                  65                  70                  75

 Ile Pro Pro Ile His Val Pro Pro Gly Tyr Ile Ser Gln Val Ile
                  80                  85                  90

 Glu Asp Ser Thr Gly Val Arg Arg Val Val Val Thr Pro Gln Ser
                  95                 100                 105

 Pro Glu Cys Tyr Pro Pro Ser Tyr Pro Ser Ala Met Ser Pro Thr
                 110                 115                 120

 His His Leu Pro Pro Tyr Leu Thr His His Pro His Phe Ile His
                 125                 130                 135

 Asn Ser His Thr Ala Tyr Tyr Pro Pro Val Thr Gly Pro Gly Asp
                 140                 145                 150

 Met Pro Pro Gln Phe Phe Pro Gln His His Leu Pro His Thr Ile
                 155                 160                 165

 Tyr Gly Glu Gln Glu Ile Ile Pro Phe Tyr Gly Met Ser Ser Tyr
                 170                 175                 180

 Ile Thr Arg Glu Asp Gln Tyr Ser Lys Pro Pro His Lys Lys Leu
                 185                 190                 195

 Lys Asp Arg Gln Ile Asp Arg Gln Asn Arg Leu Asn Arg Pro Pro
                 200                 205                 210

 Ser Ala Ile Tyr Lys Ser Ser Cys Thr Thr Val Tyr Asn Gly Tyr
                 215                 220                 225

 Gly Lys Gly His Ser Gly Gly Ser Gly Gly Gly Gly Ser Gly Ser
                 230                 235                 240

 Gly Pro Gly Ile Lys Lys Thr Glu Arg Arg Ala Arg Ser Ser Pro
                 245                 250                 255

 Lys Ser Asn Asp Ser Asp Leu Gln Glu Tyr Glu Leu Glu Val Lys
                 260                 265                 270

 Arg Val Gln Asp Ile Leu Ser Gly Ile Glu Lys Pro Gln Val Ser
                 275                 280                 285

 Asn Ile Gln Ala Arg Ala Val Val Leu Ser Trp Ala Pro Pro Val
                 290                 295                 300

 Gly Leu Ser Cys Gly Pro His Ser Gly Leu Ser Phe Pro Tyr Ser
                 305                 310                 315

 Tyr Glu Val Ala Leu Ser Asp Lys Gly Arg Asp Gly Lys Tyr Lys
                 320                 325                 330

 Ile Ile Tyr Ser Gly Glu Glu Leu Glu Cys Asn Leu Lys Asp Leu
                 335                 340                 345

 Arg Pro Ala Thr Asp Tyr His Val Arg Val Tyr Ala Met Tyr Asn
                 350                 355                 360

 Ser Val Lys Gly Ser Cys Ser Glu Pro Val Ser Phe Thr Thr His
                 365                 370                 375

 Ser Cys Ala Pro Glu Cys Pro Phe Pro Pro Lys Leu Ala His Arg
                 380                 385                 390

 Ser Lys Ser Ser Leu Thr Leu Gln Trp Lys Ala Pro Ile Asp Asn
                 395                 400                 405

 Gly Ser Lys Ile Thr Asn Tyr Leu Leu Glu Trp Asp Glu Gly Lys
                 410                 415                 420

 Arg Asn Ser Gly Phe Arg Gln Cys Phe Phe Gly Ser Gln Lys His
                 425                 430                 435

 Cys Lys Leu Thr Lys Leu Cys Pro Ala Met Gly Tyr Thr Phe Arg
                 440                 445                 450

 Leu Ala Ala Arg Asn Asp Ile Gly Thr Ser Gly Tyr Ser Gln Glu
                 455                 460                 465

 Val Val Cys Tyr Thr Leu Gly Asn Ile Pro Gln Met Pro Ser Ala
                 470                 475                 480

 Pro Arg Leu Val Arg Ala Gly Ile Thr Trp Val Thr Leu Gln Trp
                 485                 490                 495

 Ser Lys Pro Glu Gly Cys Ser Pro Glu Glu Val Ile Thr Tyr Thr
                 500                 505                 510

 Leu Glu Ile Gln Glu Asp Glu Asn Asp Asn Leu Phe His Pro Lys
                 515                 520                 525

 Tyr Thr Gly Glu Asp Leu Thr Cys Thr Val Lys Asn Leu Lys Arg
                 530                 535                 540

 Ser Thr Gln Tyr Thr Phe Arg Leu Thr Ala Ser Asn Thr Glu Gly
                 545                 550                 555

 Lys Ser Cys Pro Ser Glu Val Leu Val Cys Thr Thr Ser Pro Asp
                 560                 565                 570

 Arg Pro Gly Pro Pro Thr Arg Pro Leu Val Lys Gly Pro Val Thr
                 575                 580                 585

 Ser His Gly Phe Ser Val Lys Trp Asp Pro Pro Lys Asp Asn Gly
                 590                 595                 600

 Gly Ser Glu Ile Leu Lys Tyr Leu Leu Glu Ile Thr Asp Gly Asn
                 605                 610                 615

 Ser Glu Ala Asn Gln Trp Glu Val Ala Tyr Ser Gly Ser Ala Thr
                 620                 625                 630

 Glu Tyr Thr Phe Thr His Leu Lys Pro Gly Thr Leu Tyr Lys Leu
                 635                 640                 645

 Arg Ala Cys Cys Ile Ser Thr Gly Gly His Ser Gln Cys Ser Glu
                 650                 655                 660

 Ser Leu Pro Val Arg Thr Leu Ser Ile Ala Pro Gly Gln Cys Arg
                 665                 670                 675

 Pro Pro Arg Val Leu Gly Arg Pro Lys His Lys Glu Val His Leu
                 680                 685                 690

 Glu Trp Asp Val Pro Ala Ser Glu Ser Gly Cys Glu Val Ser Glu
                 695                 700                 705

 Tyr Ser Val Glu Met Thr Glu Pro Glu Asp Val Ala Ser Glu Val
                 710                 715                 720

 Tyr His Gly Pro Glu Leu Glu Cys Thr Val Gly Asn Leu Leu Pro
                 725                 730                 735

 Gly Thr Val Tyr Arg Phe Arg Val Arg Ala Leu Asn Asp Gly Gly
                 740                 745                 750

 Tyr Gly Pro Tyr Ser Asp Val Ser Glu Ile Thr Thr Ala Ala Gly
                 755                 760                 765

 Pro Pro Gly Gln Cys Lys Ala Pro Cys Ile Ser Cys Thr Pro Asp
                 770                 775                 780

 Gly Cys Val Leu Val Gly Trp Glu Ser Pro Asp Ser Ser Gly Ala
                 785                 790                 795

 Asp Ile Ser Glu Tyr Arg Leu Glu Trp Gly Glu Asp Glu Glu Ser
                 800                 805                 810

 Leu Glu Leu Ile Tyr His Gly Thr Asp Thr Arg Phe Glu Ile Arg
                 815                 820                 825

 Asp Leu Leu Pro Ala Ala Gln Tyr Cys Cys Arg Leu Gln Ala Phe
                 830                 835                 840

 Asn Gln Ala Gly Ala Gly Pro Tyr Ser Glu Leu Val Leu Cys Gln
                 845                 850                 855

 Thr Pro Ala Ser Ala Pro Asp Pro Val Ser Thr Leu Cys Val Leu
                 860                 865                 870

 Glu Glu Glu Pro Leu Asp Ala Tyr Pro Asp Ser Pro Ser Ala Cys
                 875                 880                 885

 Leu Val Leu Asn Trp Glu Glu Pro Cys Asn Asn Gly Ser Glu Ile
                 890                 895                 900

 Leu Ala Tyr Thr Ile Asp Leu Gly Asp Thr Ser Ile Thr Val Gly
                 905                 910                 915

 Asn Thr Thr Met His Val Met Lys Asp Leu Leu Pro Glu Thr Thr
                 920                 925                 930

 Tyr Arg Ile Arg Ile Gln Ala Ile Asn Glu Ile Gly Ala Gly Pro
                 935                 940                 945

 Phe Ser Gln Phe Ile Lys Ala Lys Thr Arg Pro Leu Pro Pro Leu
                 950                 955                 960

 Pro Pro Arg Leu Glu Cys Ala Ala Ala Gly Pro Gln Ser Leu Lys
                 965                 970                 975

 Leu Lys Trp Gly Asp Ser Asn Ser Lys Thr His Ala Ala Glu Asp
                 980                 985                 990

 Ile Val Tyr Thr Leu Gln Leu Glu Asp Arg Asn Lys Arg Phe Ile
                 995                1000                1005

 Ser Ile Tyr Arg Gly Pro Ser His Thr Tyr Lys Val Gln Arg Leu
                1010                1015                1020

 Thr Glu Phe Thr Cys Tyr Ser Phe Arg Ile Gln Ala Ala Ser Glu
                1025                1030                1035

 Ala Gly Glu Gly Pro Phe Ser Glu Thr Tyr Thr Phe Ser Thr Thr
                1040                1045                1050

 Lys Ser Val Pro Pro Thr Ile Lys Ala Pro Arg Val Thr Gln Leu
                1055                1060                1065

 Glu Gly Asn Ser Cys Glu Ile Leu Trp Glu Thr Val Pro Ser Met
                1070                1075                1080

 Lys Gly Asp Pro Val Asn Tyr Ile Leu Gln Val Leu Val Gly Arg
                1085                1090                1095

 Glu Ser Glu Tyr Lys Gln Val Tyr Lys Gly Glu Glu Ala Thr Phe
                1100                1105                1110

 Gln Ile Ser Gly Leu Gln Thr Asn Thr Asp Tyr Arg Phe Arg Val
                1115                1120                1125

 Cys Ala Cys Arg Arg Cys Leu Asp Thr Ser Gln Glu Leu Ser Gly
                1130                1135                1140

 Ala Phe Ser Pro Ser Ala Ala Phe Val Leu Gln Arg Ser Glu Val
                1145                1150                1155

 Met Leu Thr Gly Asp Met Gly Ser Leu Asp Asp Pro Lys Met Lys
                1160                1165                1170

 Ser Met Met Pro Thr Asp Glu Gln Phe Ala Ala Ile Ile Val Leu
                1175                1180                1185

 Gly Phe Ala Thr Leu Ser Ile Leu Phe Ala Phe Ile Leu Gln Tyr
                1190                1195                1200

 Phe Leu Met Lys


<210> 3255
<211> 5737
<212> DNA
<213> Homo sapien

<400> 3255
 ggcacgagca gcctttcagg cagggtggca accaactata tctgaggacc 50

 agagccattt tggggcacca gagcttgtga cctctccatc tccacccagc 100

 tgggtccagg ggccactctc agcactcacc tcagcagctg acatcataaa 150

 gcagacttgg gaacctggaa gcactctgga gaacctttcc ctgagacatg 200

 gagctttggg gccgaatgct gtgggccctc ctgtctggcc cagggaggag 250

 gggaagtacc cggggctggg ccttcagctc atggcaaccc caaccacctc 300

 tggctgggtt atccagtgcc atagaactgg tcagccactg gactggggtc 350

 tttgagaaga ggggtatccc tgaggcccgg gaatccagtg agtacatcgt 400

 ggctcatgtc cttggagcca aaacatttca gagcctgagg ccggcacttt 450

 ggacccagcc cttgacctct cagcaactac agtgtatccg ggagctgagt 500

 agccgtcgat tgcagaggat gccggtgcag tacatccttg gagagtggga 550

 cttccagggg ctcagcctaa ggatggtgcc cccagtgttt attccgcggc 600

 cagaaacaga ggaactggtt gagtgggtgc tggaagaggt ggcccagagg 650

 tcccatgctg tgggatcccc aggcagcccc ctcattctgg aggtgggctg 700

 cggatcagga gccatctccc tcagcctgct gagccagctc ccccagagcc 750

 gagtcattgc tgtggataag cgggaagctg ctatctctct gacccatgag 800

 aatgctcaga ggcttcggtt gcaggacagg atttggatca tccacctcga 850

 catgacctca gaaaggagct ggacacacct gccctggggc cccatggacc 900

 tgattgtcag caaccctccc tacgtcttcc accaggacat ggagcagctg 950

 gcccctgaga tccgcagcta tgaagacccc gcggccctgg atggtgggga 1000

 ggagggcatg gacatcatta cccacattct ggccttggca ccccggctcc 1050

 tgaaagactc tggtagtatc ttcttagaag tggacccaag gcacccggag 1100

 cttgtcagca gctggcttca gagccggcct gacctgtacc ttaatcttgt 1150

 ggctgtgcgc agggacttct gtgggaggcc ccggttcctg catatccgga 1200

 ggtctgggcc atagcatggc tgccctgtgg atgccttgtc agtgccgcca 1250

 gcctgaccag aggggaggtg gatggcactt tccagagccc aggttcttat 1300

 ggcatttccc agggttctgt gatttcccca tgctctgcat ttctaggata 1350

 tttctaggac acctggattg gctccatcac atcagagtgg ctgagggcag 1400

 ttgctctgtg ttggtgaaat tgctgtgggg gtatcggggg atatggccag 1450

 taaagtattg agagactaac aaatggtgac ctaatgtttt gtccatgact 1500

 tgcaggtccc ctgaccccct tactcccagg tagcactggg gcaagggttt 1550

 ccttctgccc cagcagggct ggcccgtcag tcccctgctt ggtagtggtg 1600

 tgggggtgca gtgtggagga aggcacgtga gtcctcactc ctggccttgg 1650

 ataccatggg tcctggcata agcagctcac tcccagtgat tgattagtcc 1700

 tccactgccc tgggtgcatg cgtacacaat tccctggcca agcctggctc 1750

 gagcacagga agctcatctg cgttttggct caaggatgac tgcctgcttt 1800

 ctggagggga gggtctggag gtctttgctg cacagttcct ggtcgcacat 1850

 ccacgttcat ttaactgaag gcttgagcca gtgaggggtg tttccttttt 1900

 atccccatag cttttagcta aaacatccct cccgagttga ccccctgggg 1950

 tttcaaataa cccatgtgtc cctggttggg gctggggaga gtgagaagct 2000

 gagatactgg gcacagggtt gtggcctcca ccccagctct ggtctgtgca 2050

 gactcatggc caccaggagg cctgcagatc cagccttcct gtcaacagcg 2100

 acaggaaatc tctaggttgg tgagtgctgg tgatgtgagc ctacatcagg 2150

 gtgggtccta agaaacatgg caaaccaggc tgtctcattc cactaactgc 2200

 cccctgccac cctggcactt cccagggcct ggcagtatgg tctgatgggc 2250

 agtatggtcc aataggcagc atcctctgct gcagctggga gagctgagtt 2300

 ccagggctgt gtcctgcagt gggaccttgg gcaactcctt tccctatgag 2350

 aagctggctc ttctgagtcc agggccaacg ccaactggca acctctttac 2400

 tcttagtcaa gtggaatgtg catgctggca tctgaatgtc cattcgccag 2450

 gcatggagag caagagaagg tatgtactgc ctgaggtcac atgacagtga 2500

 ccaagtggag acagtaagtt agatccctcc ctttggggag cctatattgc 2550

 tggagtcata cccagcctaa gtgttgccct gcactatggc tggaggacat 2600

 ttggtagagg tcacactgca gctcccagtg ccccagtgtc ctgccctgtg 2650

 cccagcccca gctgcatgga ctctgagctg cccctggctt cctttaagga 2700

 ggctgctcca gaaggaacct gggtggggag ggcgaagggg gtgcacaacc 2750

 agggcaaggc tccccacttc cttagtcccc catgctcaca gacctttgcc 2800

 tgctaaggtc ctcaccagta ttgccctttc tgtctttctc cttgtgccct 2850

 ttggctcttg ctgtcttcag cagcatctca gggtagctgc cctgacctcg 2900

 gagcagtctg tcgcccccct acacctcagc cagtcctggc ttccctgatg 2950

 gtctctccct cctggcctca ggcccattcc tgaggaaggg ccttggcgag 3000

 cttgtggatg ttgcaccaga agagagtgca gtgttggaga gtgacactgt 3050

 cggggcagct ggggccacaa gcaggagccg gcctcgggca caactttctg 3100

 cccagaaaaa tgtgcagctt gactctgctg aggaaaaggt ccaagccaag 3150

 aggactggca ggcggggcct caagcctgca gccactggct tgattgggcc 3200

 ctggacgttg agcccagatg ttggagccac accagcctgg atttcaatcc 3250

 cagaatctgc ccctcaccag gatgtgacct tgggcagatg acttcacctc 3300

 actcagcctt ggcttctaag gctgagaaat gggacttaat gcttttttat 3350

 tttataggat gcatgtgagg agcccatgga atgtgcctgg cttggcacat 3400

 tgtggcattt ttccttgcct tcctcggagg gcagacacag ggaggaagga 3450

 cccagtgccc tcaggcgtcc atctgatgca tgggaccaac ataaggcagg 3500

 cagggataca aggcagtctg gaaagaaggg aaggcaggag tttcagtctt 3550

 gggctcttga ctcctcgctg ttgtctagag atggagccag caggctggta 3600

 gcctggcagc ctacatctcc cctcagcctc tcctcactat ggccccagtg 3650

 ccttgaggcc caggccaggg cagccagtgg ctctagctca gggaaagcca 3700

 ggcccacctg ccctatcccc tcccttgctc ctgaggccaa agccagagac 3750

 tcgaacagcc tccccaccac caccagcata tgtcaaggag cacttgcagg 3800

 cagaatggga ggaggacatg gagctgatgg agtccaggct gtgcaagccc 3850

 ctgaggtctt gagagatgtg cccactgccc gtgcagcctc cttcagccag 3900

 agcccagagc atagacagga gtgtaggagt ccctgtttga tgtactctgg 3950

 gagagtaatt ctatctcctc ttctgatagt tggggaaact gaggccttgt 4000

 ctcacagttg gatgcttttc ccagttgtca gtgggtttct ccatgggtct 4050

 catacagctg ccttattgaa ataggccccg aaccccctaa atgcaaaaaa 4100

 tactcttttt tgctccttta cccccacctg gaccctgggc tattggctgc 4150

 tcccaatcct tgccccaaac acttagctgg ctccccatga cttaagtgtg 4200

 ttctcttgtg tcctatggaa tccagttctg aagaggtggg ggaggacaac 4250

 tgtgggaaaa gccctggggg cccctcccaa ggccccatca gtgctctgag 4300

 taggctgtca tcagaacaaa agggctccac tgctgacaag gtttgagaac 4350

 tgctggcttg aggtgagaac ccctttaacc tctgcgggac agcatgtctt 4400

 tccctatcca ccttcgattc ttttctcttt tttttcttca ttggctcctt 4450

 cttagtggat tctcttctct actgccctgg gcttcagcct ttgtgcagta 4500

 ctctcgatgc cctgaacaca caccttccct ttgcccaggc ggtgcaaaca 4550

 atccacttct tcaagctcca acacaaatgc tgcctccttt aggatgcctg 4600

 ctctgtgctc tccctgcctc ccctagccca tacctctgct ggcaccttct 4650

 gtaccatgcc ttcagaaacc ttcttatccc cctcatctct ggggccccct 4700

 gtggatctgg catacccaag ttcagtaaat gtctatcagt aagctgatgg 4750

 tacatgcatt ttctagaata gagctgggac ttcccatgtg gcccacatct 4800

 gacctggcag cccatgtatt ccggtcatta gggatgggaa gccatgagga 4850

 cctggccttc tgcccgaccc aggcagccat tcaagttgag caatggccac 4900

 ttcgaagact caagtgcacc tgatccctgc gcaacagcca caccaggaga 4950

 acaggctgtc cttggcggca gtaggagcag gcgccaggtt tcctggagct 5000

 cttggcttca gccagccccc agccagagtc ctggctagga cagtgacctg 5050

 atctcctcct catgaccttc tgccctggac aagccccctg aactggattt 5100

 gggactgtca aagcaactct acccctgctc tggtaggctg aacagtgacc 5150

 ccccaaaatg gcagtgtctt aatcacctaa accttaacat gtgactatat 5200

 taccttcaca tagcaaaatg gactttgcag atgtgattaa ggatcttgag 5250

 atggaaggag tatcctggat ttttcaggta aactgagtat aatcacaagg 5300

 gcctctgtaa aggaggcagg agtgtcagag tgacggaaga aaatgtatgt 5350

 aacaatggaa gcagaggtca gagtgatgca attgctggag gaagagccat 5400

 gagccgagga atgcagacag cctcttctcc tctggggcct caagaagaat 5450

 gcagtcctgc caataccttg attttaagcc ctgtgaaact gatttcagat 5500

 tgctgacctc cagaacagta agatcataaa tttgtgttgt tttcacatgt 5550

 gtgaaaacac atgtgtgata atttgttaca gcagccacgg gaaacgaata 5600

 tagattgtgg tgcccaaatt agagtgctgc tgtaacacac gcctactgat 5650

 tgaagtggct ttggaattgc aacgtggaaa tgggcagagg ctggaagaat 5700

 tttgagagtc atgataaatt gccttaacca ccaaaaa 5737

<210> 3256
<211> 338
<212> PRT
<213> Homo sapien

<400> 3256
 Met Glu Leu Trp Gly Arg Met Leu Trp Ala Leu Leu Ser Gly Pro
   1               5                  10                  15

 Gly Arg Arg Gly Ser Thr Arg Gly Trp Ala Phe Ser Ser Trp Gln
                  20                  25                  30

 Pro Gln Pro Pro Leu Ala Gly Leu Ser Ser Ala Ile Glu Leu Val
                  35                  40                  45

 Ser His Trp Thr Gly Val Phe Glu Lys Arg Gly Ile Pro Glu Ala
                  50                  55                  60

 Arg Glu Ser Ser Glu Tyr Ile Val Ala His Val Leu Gly Ala Lys
                  65                  70                  75

 Thr Phe Gln Ser Leu Arg Pro Ala Leu Trp Thr Gln Pro Leu Thr
                  80                  85                  90

 Ser Gln Gln Leu Gln Cys Ile Arg Glu Leu Ser Ser Arg Arg Leu
                  95                 100                 105

 Gln Arg Met Pro Val Gln Tyr Ile Leu Gly Glu Trp Asp Phe Gln
                 110                 115                 120

 Gly Leu Ser Leu Arg Met Val Pro Pro Val Phe Ile Pro Arg Pro
                 125                 130                 135

 Glu Thr Glu Glu Leu Val Glu Trp Val Leu Glu Glu Val Ala Gln
                 140                 145                 150

 Arg Ser His Ala Val Gly Ser Pro Gly Ser Pro Leu Ile Leu Glu
                 155                 160                 165

 Val Gly Cys Gly Ser Gly Ala Ile Ser Leu Ser Leu Leu Ser Gln
                 170                 175                 180

 Leu Pro Gln Ser Arg Val Ile Ala Val Asp Lys Arg Glu Ala Ala
                 185                 190                 195

 Ile Ser Leu Thr His Glu Asn Ala Gln Arg Leu Arg Leu Gln Asp
                 200                 205                 210

 Arg Ile Trp Ile Ile His Leu Asp Met Thr Ser Glu Arg Ser Trp
                 215                 220                 225

 Thr His Leu Pro Trp Gly Pro Met Asp Leu Ile Val Ser Asn Pro
                 230                 235                 240

 Pro Tyr Val Phe His Gln Asp Met Glu Gln Leu Ala Pro Glu Ile
                 245                 250                 255

 Arg Ser Tyr Glu Asp Pro Ala Ala Leu Asp Gly Gly Glu Glu Gly
                 260                 265                 270

 Met Asp Ile Ile Thr His Ile Leu Ala Leu Ala Pro Arg Leu Leu
                 275                 280                 285

 Lys Asp Ser Gly Ser Ile Phe Leu Glu Val Asp Pro Arg His Pro
                 290                 295                 300

 Glu Leu Val Ser Ser Trp Leu Gln Ser Arg Pro Asp Leu Tyr Leu
                 305                 310                 315

 Asn Leu Val Ala Val Arg Arg Asp Phe Cys Gly Arg Pro Arg Phe
                 320                 325                 330

 Leu His Ile Arg Arg Ser Gly Pro
                 335

<210> 3257
<211> 1589
<212> DNA
<213> Homo sapien

<400> 3257
 gtctcttcct cgctccctct ctttctctcc tccctctgcc ttcccagtgc 50

 ataaagtctc tgtcgctccc ggaacttgtt ggcaatgcct attttttggc 100

 tttcccccgc gttctctaaa ctaactattt aaaggtctgc ggtcgcaaat 150

 ggtttgacta aacgtaggat gggacttaag ttgaacggca gatatatttc 200

 actgatcctc gcggtgcaaa tagcgtatct ggtgcaggcc gtgagagcag 250

 cgggcaagtg cgatgcggtc ttcaagggct tttcggactg tttgctcaag 300

 ctgggcgaca gcatggccaa ctacccgcag ggcctggacg acaagacgaa 350

 catcaagacc gtgtgcacat actgggagga tttccacagc tgcacggtca 400

 cagcccttac ggattgccag gaaggggcga aagatatgtg ggataaactg 450

 agaaaagaat ccaaaaacct caacatccaa ggcagcttat tcgaactctg 500

 cggcagcggc aacggggcgg cggggtccct gctcccggcg ttcccggtgc 550

 tcctggtgtc tctctcggca gctttagcga cctggctttc cttctgagcg 600

 tggggccagc tccccccgcg cgcccaccca cactcactcc atgctcccgg 650

 aaatcgagag gaagatccat tagttctttg gggacgttgt gattctctgt 700

 gatgctgaaa acactcatat aggattgtgg gaaatcctga ttctcttttt 750

 tatttcgttt gatttcttgt gttttatttg ccaaatgtta ccaatcagtg 800

 agcaagcaag cacagccaaa atcggacctc agctttagtc cgtcttcaca 850

 cacaaataag aaaacggcaa acccacccca ttttttaatt ttattattat 900

 taattttttt tgttggcaaa agaatctcag gaacggccct gggccaccta 950

 ctatattaat catgctagta acatgaaaaa tgatgggctc ctcctaatag 1000

 gaaggcgagg agaggagaag gccaggggaa tgaattcaag agagatgtcc 1050

 acggccgaaa catacggtga ataattcacg ctcacgtcgt tcttccacag 1100

 tatcttgttt tgatcatttc cactgcacat ttctcctcaa gaaaagcgaa 1150

 aggacagact gttggctttg tgtttggagg ataggaggga gagagggaag 1200

 gggctgagga aatctctggg gtaagagtaa aggcttccag aagacatgct 1250

 gctatggtca ctgaggggtt agctttatct gctgttgttg atgcatccgt 1300

 ccaagttcac tgcctttatt ttccctcctc cctcttgttt tagctgttac 1350

 acacacagta atacctgaat atccaacggt atagatcaca agggggggat 1400

 gttaaatgtt aatctaaaat atagctaaaa aaagattttg acataaaaga 1450

 gccttgattt taaaaaaaaa agagagagag atgtaattta aaaagtttat 1500

 tataaattaa attcagcaaa aaaagatttg ctacaaagta tagagaagta 1550

 taaaataaaa gttattgttt gaaaaaaaaa aaaaaaaaa 1589

<210> 3258
<211> 142
<212> PRT
<213> Homo sapien

<400> 3258
 Met Gly Leu Lys Leu Asn Gly Arg Tyr Ile Ser Leu Ile Leu Ala
   1               5                  10                  15

 Val Gln Ile Ala Tyr Leu Val Gln Ala Val Arg Ala Ala Gly Lys
                  20                  25                  30

 Cys Asp Ala Val Phe Lys Gly Phe Ser Asp Cys Leu Leu Lys Leu
                  35                  40                  45

 Gly Asp Ser Met Ala Asn Tyr Pro Gln Gly Leu Asp Asp Lys Thr
                  50                  55                  60

 Asn Ile Lys Thr Val Cys Thr Tyr Trp Glu Asp Phe His Ser Cys
                  65                  70                  75

 Thr Val Thr Ala Leu Thr Asp Cys Gln Glu Gly Ala Lys Asp Met
                  80                  85                  90

 Trp Asp Lys Leu Arg Lys Glu Ser Lys Asn Leu Asn Ile Gln Gly
                  95                 100                 105

 Ser Leu Phe Glu Leu Cys Gly Ser Gly Asn Gly Ala Ala Gly Ser
                 110                 115                 120

 Leu Leu Pro Ala Phe Pro Val Leu Leu Val Ser Leu Ser Ala Ala
                 125                 130                 135

 Leu Ala Thr Trp Leu Ser Phe
                 140

<210> 3259
<211> 2568
<212> DNA
<213> Homo sapien

<400> 3259
 aactacgaag atggcggttg cgcgcttggc agctgtggcg gcctgggtac 50

 cttgtcggag ctggggctgg gcagccgtcc ccttcggtcc ccaccgtggc 100

 ctcagcgtgc tgcttgcacg gatacctcag cgggcgccac ggtggctccc 150

 agcttgtaga caaaagacgt cactctcatt ccttaatcga ccagaccttc 200

 caaacctggc ttataagaag ctaaaaggca aaagtccagg aattatcttc 250

 atccctggct atctttctta tatgaatggt acaaaagcgt tggcgattga 300

 ggagttttgc aaatctctag gtcacgcctg cataaggttt gattactcag 350

 gagttggaag ttcagatggt aactcagagg aaagcacact ggggaaatgg 400

 agaaaagatg ttctttctat aattgatgac ttagctgatg ggccacagat 450

 tcttgttgga tctagcctcg gagggtggct tatgcttcat gctgcaattg 500

 cacgaccaga gaaggtcgtg gctcttattg gtgtagctac agctgcagat 550

 accttagtga caaagtttaa tcagcttcct gttgagctaa aaaaggaagt 600

 agagatgaaa ggtgtgtgga gcatgccatc aaaatactct gaagaaggag 650

 tttataacgt tcagtacagt ttcattaaag aagctgaaca tcactgcttg 700

 ttacatagcc caattcctgt gaactgcccc ataagattgc tccatggcat 750

 gaaggatgac attgtacctt ggcatacatc aatgcaggtt gccgatcgag 800

 tactcagcac agatgtggat gtcatcctcc gaaaacacag tgatcaccga 850

 atgagggaaa aagcagacat tcaacttctt gtttacacta ttgatgactt 900

 aattgataag ctctcaacta tagttaacta gtatcacatg tttagttggt 950

 atgtaaacta atgtatccag aagattggaa gagggataag aaatgaaaga 1000

 tcctgatact ttaggctttt ccctttcctc tattttgtaa atataagatg 1050

 agtattattt aatgatgtat ttgcataagt aatgcaaatt gtgaagaagg 1100

 accagctgct gtttagaaaa ttttctcctt ccttctgtcc ttgatttttt 1150

 ttcattaaag tatttccttt ttttaattca agaaaagttt acctttctta 1200

 tgcttatgtt agctatgcca gctcttaatt gcatcctttt ctaattagga 1250

 ttattaataa agcgtgaata ttttgttttt tattatagac agaaatttgt 1300

 aacattactt ctgatttgaa aatgcaattc acaaaatata gggaaatttt 1350

 tattgaataa atttgaaatg atggagaaat ttcagaagca taataaagtt 1400

 cacaataagg ataatacttt atataatgta taaagtatat ataatataat 1450

 atatatgtta tataaactgc acattatatt caaacttaaa attgagcttt 1500

 ttttttaaag gcccaaaatt gtacagtgat acaaggagct atttctaaaa 1550

 tttggcttat gtataatata tttaaatggg gaatttcatc taaagcaatg 1600

 atgtagtatt tttaatattc tgattggtaa aattaaagag gaaattaatc 1650

 tttatatatt atttcttgca gaaacattca ttattttatt aatattgccc 1700

 taagtacaac taggcaagtg attgccacct aaatcagaag acgttctaaa 1750

 gtcagtaaga aagtgtgaaa tgctagtata aaggttattt tttttctttc 1800

 ctaaataact aaagtgaggt gtagattgag ccttgatatt atttagttaa 1850

 tgttttttat taattaattt tggctggact ttatttagct tgattaggtt 1900

 attatctgtc aaacctttta agttgacaac atgactcata tatatacatg 1950

 tgtataagat gagcatgtgt caaagactta ttcgactcat taatgaggaa 2000

 accagcagat agtaaacctg gttcaaagta caattcaaga aactgagtat 2050

 ttatgggcat tgaagaaaaa atgttgagat aaaattgctg tgcagaaaaa 2100

 agtgttaatg aagccgacct gactacttaa ccttagagac ctgctttaca 2150

 aggttggccc ttgattggca tctgggaact tggagttcag ggggcttcca 2200

 ccattcccag aactgatcaa agtagcttac tatatctaaa ctgtaaaaca 2250

 atatagtttc tcctgaacac ctgctttcct tctgggagtc tggaattttg 2300

 gtatgtgcca ggcagagact acctttgtga ccagctccca gtaaaaaccc 2350

 caggcactca gtctctaaca agcttttctg gttgacagtg tttcacaagt 2400

 gctgttacaa ctggttgctg ggagaattaa gctcatcctc tgtgattcca 2450

 ctggcggagg attcttggaa gcttgcactt agtttcccct gacttcaccc 2500

 catgtgtctt ttttcctttg ctgattttgt tttgtatcct ttcactgtaa 2550

 taaatcatgg ccgtgagc 2568

<210> 3260
<211> 306
<212> PRT
<213> Homo sapien

<400> 3260
 Met Ala Val Ala Arg Leu Ala Ala Val Ala Ala Trp Val Pro Cys
   1               5                  10                  15

 Arg Ser Trp Gly Trp Ala Ala Val Pro Phe Gly Pro His Arg Gly
                  20                  25                  30

 Leu Ser Val Leu Leu Ala Arg Ile Pro Gln Arg Ala Pro Arg Trp
                  35                  40                  45

 Leu Pro Ala Cys Arg Gln Lys Thr Ser Leu Ser Phe Leu Asn Arg
                  50                  55                  60

 Pro Asp Leu Pro Asn Leu Ala Tyr Lys Lys Leu Lys Gly Lys Ser
                  65                  70                  75

 Pro Gly Ile Ile Phe Ile Pro Gly Tyr Leu Ser Tyr Met Asn Gly
                  80                  85                  90

 Thr Lys Ala Leu Ala Ile Glu Glu Phe Cys Lys Ser Leu Gly His
                  95                 100                 105

 Ala Cys Ile Arg Phe Asp Tyr Ser Gly Val Gly Ser Ser Asp Gly
                 110                 115                 120

 Asn Ser Glu Glu Ser Thr Leu Gly Lys Trp Arg Lys Asp Val Leu
                 125                 130                 135

 Ser Ile Ile Asp Asp Leu Ala Asp Gly Pro Gln Ile Leu Val Gly
                 140                 145                 150

 Ser Ser Leu Gly Gly Trp Leu Met Leu His Ala Ala Ile Ala Arg
                 155                 160                 165

 Pro Glu Lys Val Val Ala Leu Ile Gly Val Ala Thr Ala Ala Asp
                 170                 175                 180

 Thr Leu Val Thr Lys Phe Asn Gln Leu Pro Val Glu Leu Lys Lys
                 185                 190                 195

 Glu Val Glu Met Lys Gly Val Trp Ser Met Pro Ser Lys Tyr Ser
                 200                 205                 210

 Glu Glu Gly Val Tyr Asn Val Gln Tyr Ser Phe Ile Lys Glu Ala
                 215                 220                 225

 Glu His His Cys Leu Leu His Ser Pro Ile Pro Val Asn Cys Pro
                 230                 235                 240

 Ile Arg Leu Leu His Gly Met Lys Asp Asp Ile Val Pro Trp His
                 245                 250                 255

 Thr Ser Met Gln Val Ala Asp Arg Val Leu Ser Thr Asp Val Asp
                 260                 265                 270

 Val Ile Leu Arg Lys His Ser Asp His Arg Met Arg Glu Lys Ala
                 275                 280                 285

 Asp Ile Gln Leu Leu Val Tyr Thr Ile Asp Asp Leu Ile Asp Lys
                 290                 295                 300

 Leu Ser Thr Ile Val Asn
                 305

<210> 3261
<211> 2739
<212> DNA
<213> Homo sapien

<400> 3261
 cgcacgcgca gtcgtatccg tgtgatgggc gggctgttga cggcgctgcg 50

 atggctgcct gcgagggcag gagaagcgga gctctcggtt cctctcagtc 100

 ggacttcctg acgccgccag tgggcggggc cccttgggcc gtcgccacca 150

 ctgtagtcat gtacccaccg ccgccgccgc cgcctcatcg ggacttcatc 200

 tcggtgacgc tgagctttgg cgagagctat gacaacagca agagttggcg 250

 gcggcgctcg tgctggagga aatggaagca actgtcgaga ttgcagcgga 300

 atatgattct cttcctcctt gcctttctgc ttttctgtgg actcctcttc 350

 tacatcaact tggctgacca ttggaaagct ctggctttca ggctagagga 400

 agagcagaag atgaggccag aaattgctgg gttaaaacca gcaaatccac 450

 ccgtcttacc agctcctcag aaggcggaca ccgaccctga gaacttacct 500

 gagatttcgt cacagaagac acaaagacac atccagcggg gaccacctca 550

 cctgcagatt agacccccaa gccaagacct gaaggatggg acccaggagg 600

 aggccacaaa aaggcaagaa gcccctgtgg atccccgccc ggaaggagat 650

 ccgcagagga cagtcatcag ctggagggga gcggtgatcg agcctgagca 700

 gggcaccgag ctcccttcaa gaagagcaga agtgcccacc aagcctcccc 750

 tgccaccggc caggacacag ggcacaccag tgcatctgaa ctatcgccag 800

 aagggcgtga ttgacgtctt cctgcatgca tggaaaggat accgcaagtt 850

 tgcatggggc catgacgagc tgaagcctgt gtccaggtcc ttcagtgagt 900

 ggtttggcct cggtctcaca ctgatcgacg cgctggacac catgtggatc 950

 ttgggtctga ggaaagaatt tgaggaagcc aggaagtggg tgtcgaagaa 1000

 gttacacttt gaaaaggacg tggacgtcaa cctgtttgag agcacgatcc 1050

 gcatcctggg ggggctcctg agtgcctacc acctgtctgg ggacagcctc 1100

 ttcctgagga aagctgagga ttttggaaat cggctaatgc ctgccttcag 1150

 aacaccatcc aagattcctt actcggatgt gaacatcggt actggagttg 1200

 cccacccgcc acggtggacc tccgacagca ctgtggccga ggtgaccagc 1250

 attcagctgg agttccggga gctctcccgt ctcacagggg ataagaagtt 1300

 tcaggaggca gtggagaagg tgacacagca catccacggc ctgtctggga 1350

 agaaggatgg gctggtgccc atgttcatca atacccacag tggcctcttc 1400

 acccacctgg gcgtattcac gctgggcgcc agggccgaca gctactatga 1450

 gtacctgctg aagcagtgga tccagggcgg gaagcaggag acacagctgc 1500

 tggaagacta cgtggaagcc atcgagggtg tcagaacgca cctgctgcgg 1550

 cactccgagc ccagtaagct cacctttgtg ggggagcttg cccacggccg 1600

 cttcagtgcc aagatggacc acctggtgtg cttcctgcca gggacgctgg 1650

 ctctgggcgt ctaccacggc ctgcccgcca gccacatgga gctggcccag 1700

 gagctcatgg agacttgtta ccagatgaac cggcagatgg agacggggct 1750

 gagtcccgag atcgtgcact tcaaccttta cccccagccg ggccgtcggg 1800

 acgtggaggt caagccagca gacaggcaca acctgctgcg gccagagacc 1850

 gtggagagcc tgttctacct gtaccgcgtc acaggggacc gcaaatacca 1900

 ggactggggc tgggagattc tgcagagctt cagccgattc acacgggtcc 1950

 cctcgggtgg ctattcttcc atcaacaatg tccaggatcc tcagaagccc 2000

 gagcctaggg acaagatgga gagcttcttc ctgggggaga cgctcaagta 2050

 tctgttcttg ctcttctccg atgacccaaa cctgctcagc ctggacgcct 2100

 acgtgttcaa caccgaagcc caccctctgc ctatctggac ccctgcctag 2150

 ggtggatggc tgctggtgtg gggacttcgg gtgggcagag gcaccttgct 2200

 gggtctgtgg cattttccaa ggcccacgta gcaccggcaa ccgccaagtg 2250

 gcccaggctc tgaactggct ctgggctcct cctcgtctct gctttaatca 2300

 ggacaccgtg aggacaagtg aggccgtcag tcttggtgtg atgcggggtg 2350

 ggctgggccg ctggagcctc cgcctgcttc ctccagaaga cacgaatcat 2400

 gactcacgat tgctgaagcc tgagcaggtc tctgtgggcc gaccagaggg 2450

 gggcttcgag gtggtccctg gtactggggt gaccgagtgg acagcccagg 2500

 gtgcagctct gcccgggctc gtgaagcctc agrtgtcccc aatccaaggg 2550

 tctggagggg ctgccgtgac tccagaggcc tgaggctcca gggctggctc 2600

 tggtgtttac aagctggact cagggatcct cctggccgcc ccgcaggggg 2650

 cttggagggc tggacggcaa gtccgtctag ctcacgggcc cctccagtgg 2700

 aatgggtctt ttcggtggag ataaaagttg atttgctct 2739

<210> 3262
<211> 699
<212> PRT
<213> Homo sapien

<400> 3262
 Met Ala Ala Cys Glu Gly Arg Arg Ser Gly Ala Leu Gly Ser Ser
   1               5                  10                  15

 Gln Ser Asp Phe Leu Thr Pro Pro Val Gly Gly Ala Pro Trp Ala
                  20                  25                  30

 Val Ala Thr Thr Val Val Met Tyr Pro Pro Pro Pro Pro Pro Pro
                  35                  40                  45

 His Arg Asp Phe Ile Ser Val Thr Leu Ser Phe Gly Glu Ser Tyr
                  50                  55                  60

 Asp Asn Ser Lys Ser Trp Arg Arg Arg Ser Cys Trp Arg Lys Trp
                  65                  70                  75

 Lys Gln Leu Ser Arg Leu Gln Arg Asn Met Ile Leu Phe Leu Leu
                  80                  85                  90

 Ala Phe Leu Leu Phe Cys Gly Leu Leu Phe Tyr Ile Asn Leu Ala
                  95                 100                 105

 Asp His Trp Lys Ala Leu Ala Phe Arg Leu Glu Glu Glu Gln Lys
                 110                 115                 120

 Met Arg Pro Glu Ile Ala Gly Leu Lys Pro Ala Asn Pro Pro Val
                 125                 130                 135

 Leu Pro Ala Pro Gln Lys Ala Asp Thr Asp Pro Glu Asn Leu Pro
                 140                 145                 150

 Glu Ile Ser Ser Gln Lys Thr Gln Arg His Ile Gln Arg Gly Pro
                 155                 160                 165

 Pro His Leu Gln Ile Arg Pro Pro Ser Gln Asp Leu Lys Asp Gly
                 170                 175                 180

 Thr Gln Glu Glu Ala Thr Lys Arg Gln Glu Ala Pro Val Asp Pro
                 185                 190                 195

 Arg Pro Glu Gly Asp Pro Gln Arg Thr Val Ile Ser Trp Arg Gly
                 200                 205                 210

 Ala Val Ile Glu Pro Glu Gln Gly Thr Glu Leu Pro Ser Arg Arg
                 215                 220                 225

 Ala Glu Val Pro Thr Lys Pro Pro Leu Pro Pro Ala Arg Thr Gln
                 230                 235                 240

 Gly Thr Pro Val His Leu Asn Tyr Arg Gln Lys Gly Val Ile Asp
                 245                 250                 255

 Val Phe Leu His Ala Trp Lys Gly Tyr Arg Lys Phe Ala Trp Gly
                 260                 265                 270

 His Asp Glu Leu Lys Pro Val Ser Arg Ser Phe Ser Glu Trp Phe
                 275                 280                 285

 Gly Leu Gly Leu Thr Leu Ile Asp Ala Leu Asp Thr Met Trp Ile
                 290                 295                 300

 Leu Gly Leu Arg Lys Glu Phe Glu Glu Ala Arg Lys Trp Val Ser
                 305                 310                 315

 Lys Lys Leu His Phe Glu Lys Asp Val Asp Val Asn Leu Phe Glu
                 320                 325                 330

 Ser Thr Ile Arg Ile Leu Gly Gly Leu Leu Ser Ala Tyr His Leu
                 335                 340                 345

 Ser Gly Asp Ser Leu Phe Leu Arg Lys Ala Glu Asp Phe Gly Asn
                 350                 355                 360

 Arg Leu Met Pro Ala Phe Arg Thr Pro Ser Lys Ile Pro Tyr Ser
                 365                 370                 375

 Asp Val Asn Ile Gly Thr Gly Val Ala His Pro Pro Arg Trp Thr
                 380                 385                 390

 Ser Asp Ser Thr Val Ala Glu Val Thr Ser Ile Gln Leu Glu Phe
                 395                 400                 405

 Arg Glu Leu Ser Arg Leu Thr Gly Asp Lys Lys Phe Gln Glu Ala
                 410                 415                 420

 Val Glu Lys Val Thr Gln His Ile His Gly Leu Ser Gly Lys Lys
                 425                 430                 435

 Asp Gly Leu Val Pro Met Phe Ile Asn Thr His Ser Gly Leu Phe
                 440                 445                 450

 Thr His Leu Gly Val Phe Thr Leu Gly Ala Arg Ala Asp Ser Tyr
                 455                 460                 465

 Tyr Glu Tyr Leu Leu Lys Gln Trp Ile Gln Gly Gly Lys Gln Glu
                 470                 475                 480

 Thr Gln Leu Leu Glu Asp Tyr Val Glu Ala Ile Glu Gly Val Arg
                 485                 490                 495

 Thr His Leu Leu Arg His Ser Glu Pro Ser Lys Leu Thr Phe Val
                 500                 505                 510

 Gly Glu Leu Ala His Gly Arg Phe Ser Ala Lys Met Asp His Leu
                 515                 520                 525

 Val Cys Phe Leu Pro Gly Thr Leu Ala Leu Gly Val Tyr His Gly
                 530                 535                 540

 Leu Pro Ala Ser His Met Glu Leu Ala Gln Glu Leu Met Glu Thr
                 545                 550                 555

 Cys Tyr Gln Met Asn Arg Gln Met Glu Thr Gly Leu Ser Pro Glu
                 560                 565                 570

 Ile Val His Phe Asn Leu Tyr Pro Gln Pro Gly Arg Arg Asp Val
                 575                 580                 585

 Glu Val Lys Pro Ala Asp Arg His Asn Leu Leu Arg Pro Glu Thr
                 590                 595                 600

 Val Glu Ser Leu Phe Tyr Leu Tyr Arg Val Thr Gly Asp Arg Lys
                 605                 610                 615

 Tyr Gln Asp Trp Gly Trp Glu Ile Leu Gln Ser Phe Ser Arg Phe
                 620                 625                 630

 Thr Arg Val Pro Ser Gly Gly Tyr Ser Ser Ile Asn Asn Val Gln
                 635                 640                 645

 Asp Pro Gln Lys Pro Glu Pro Arg Asp Lys Met Glu Ser Phe Phe
                 650                 655                 660

 Leu Gly Glu Thr Leu Lys Tyr Leu Phe Leu Leu Phe Ser Asp Asp
                 665                 670                 675

 Pro Asn Leu Leu Ser Leu Asp Ala Tyr Val Phe Asn Thr Glu Ala
                 680                 685                 690

 His Pro Leu Pro Ile Trp Thr Pro Ala
                 695

<210> 3263
<211> 4431
<212> DNA
<213> Homo sapien

<400> 3263
 tctgttaaat gttccgaagc cactgccaaa acaactgtgg gagaccaagg 50

 agattcagtc cctgtcagga cgccctcgat cctgtgatgt tggaggtggc 100

 aatgcttttc cacataatgg tcaaaaccta ggcctctcac ccttcttggg 150

 gaccttgaac actggagggt cattgccaga tctaaccaac ctccactact 200

 cgacacccct gccagcctcc ctggacacca ccgaccacca ctttggcagt 250

 atgagtgtgg ggaatagtgt gaacaacatc ccagctgcta tgacccacct 300

 gggtataaga agctcctctg gtctccagag ttctcggagt aacccctcca 350

 tccaagccac gctcaataag actgtgcttt cctcttcctt aaataaccac 400

 ccacagacat ctgttcccaa cgcatctgct cttcaccctt cgctccgtct 450

 gttttccctt agcaacccat ctctttccac cacaaacctg agcggcccgt 500

 ctcggcgtcg gcagcctccc gtcagccctc tcacgctttc tcctggccct 550

 gaagcacatc aaggtttcag cagacagctg tcttcaacca gcccactggc 600

 cccatatcct acctcccaga tggtgtcctc agaccgaagc caactttcct 650

 ttctgcccac agaagctcaa gcccaggtgt cgccgccacc cccttaccct 700

 gcaccccagg agctcaccca gcccctcctg cagcagcccc gcgcccctga 750

 ggcccctgcc cagcagcccc aggcagcctc ctcactgcca cagtcagact 800

 ttcagcttct cccggcccag ggctcatctt tgaccaactt cttcccagat 850

 gtgggttttg accagcagtc catgaggcca ggccctgcct ttcctcaaca 900

 ggtgcctctg gtgcaacaag gttcccgaga actgcaggac tcttttcatt 950

 tgagaccaag cccgtattcc aactgcggga gtctctcgaa caccatcctg 1000

 ccagactcca gcaccagcct gttcaaagac ctcaacagtg cgctggcagg 1050

 cctgcctgag gtcagcctga acgtggacac tccatttcca ctggaagagg 1100

 agctgcagat tgaacccctg agcctggacg gactcaacat gttaagtgac 1150

 tccagcatgg gcctgctgga cccctctgtt gaagagacgt ttcgagctga 1200

 cagactgtga acagaaggca gtggaacaga agaatgtttt tctgcaacag 1250

 ccaaaataga atggaataga atgaagccag ctgataccac gggctttcgt 1300

 tatcttgaca tagaaggaag caatgccacg gctccagggt ttcagatgag 1350

 atcccatctc agacactgtg gcttcctcca gatcacacag ctttgtactg 1400

 cctctcccgc ctgtggccaa agtcgtgttg cagcaggcag gctgcttgga 1450

 gcttcccatg aactggaaag ctcacctcca ctgcatcttt ttactggcca 1500

 tccagtcagc cgatgtgtaa gagtaggaaa tactgtgtca ctggaggcct 1550

 ccgtagcatt gtgtagtgtg ctcagaacca ctgatctccg tccgcaccga 1600

 aggcgggccc ggagtgggag gctcggcctg gggcggcggc accggagagg 1650

 gcacctcgat gcctgctctg acctgaccca gagggcgagg ccctccagcg 1700

 ggggacattc ccaggctgag tggaccccac ggctctctcc cacgcctgga 1750

 ttacgacatg aagtttttac cacaagcccg agggcaggct tgagttaggc 1800

 agactgaagg ctaattttca ttttctccca gctggtttct gctgcttcag 1850

 aaaagtacac cttttcctta tggaccagag gaagaggaag accattttat 1900

 cagtcactga aaagagtccc ctggcactga tgagcctgaa gagaactgtg 1950

 ctcctcctcg ggggctgggg aaggaagaca gggactgcag gtgtctcata 2000

 ctcagtggcc tccagacaaa ctccagacaa gcacagacct ccccactaag 2050

 agcagccaga gggagctggt gaggccctaa ccccacccac cgagcaactg 2100

 agcttcccca tccctcccca gagctgtgtc tctgtgggct gggagtctaa 2150

 tgtcaccccc ctagaccgta agctccttga gggcagggac agtgccttat 2200

 cattgttgaa cccgtagcac ctaacacgtg cgtggcagca cagtcgtgtg 2250

 ctggagtgag tgctgcagaa ccgtgcgtgc agcgcatgat gaatgagtgc 2300

 gtccgccatg ccgtaaggca ggctcacctg tagctatccc cttccctgcc 2350

 agatcttctc agagctttag cttttctagc actcgtgcct atggtgaagc 2400

 atgcacttta atatgctttt aacactaggt gaccaaatca cagtgaagcc 2450

 ggacactgca ttctccttgg gctgtgctcc acgcgggtgg gtgggagctg 2500

 tcttctgagt acatccggaa gggctgagca ggtgagtgcc ctgagcatcc 2550

 tggctgggcc ccacccagga agatcttcct tctcagatcc acgtttggct 2600

 ctaaattgct tcaagtagag attcattctt tgaggttgaa aaaatagttt 2650

 atagtaaaac gaaggcctaa ttcatggaag catcattagt catcaatacc 2700

 ttctcataaa atagatgggc cagatttcca ccaccgcctg cctcctctaa 2750

 cttgggtgat gccagtaggt ttgaaggggg cagagcactg cagggggagg 2800

 ggggggtcta ggctgtgaga ggacagggtg gagaggagga gaaccctgaa 2850

 ggagagacgg aagatgccag gacctttgct tggacagcca ttgcccttcc 2900

 aggagaccct ggagtgtact gagggttgct ggactgttcc acccagagga 2950

 gcaaggctgt acaatgaggg tctggatctg gcacacctgt cccttatgta 3000

 aaaggagtcg tggtcacaag accctgggct ggttagcctc tcccgacctc 3050

 attccatttc tatcttctga ccttgcctct catctttaaa ataaccctca 3100

 tggggtgccc ctccaccttc ctctggaatc caagtattcc tgtttcacat 3150

 ttgccccaaa tctttgctgt ggaattggga aatcaaacca gagtcctcct 3200

 cgcctgattt ccagctcagg aagggcctgc tggcctgccc tgttcccagt 3250

 tacactttca gatccctttg tgctcaagat ctcagagggg gtggcttttt 3300

 gttaaagagc cttcagtcgc aatgctaccc agcaccccat gtgccaaaag 3350

 aaaccagctc ctgtgtcaaa gggcttccaa acctgatctc actctcaaca 3400

 ggcgatggtg ctgatgtttc aagaattgtg tttttataaa acagaggtct 3450

 cagcatagtc actcttcaca tagtgcctta cccatgggta tcgtcatatc 3500

 cgggtcccag ttcagtttgt ctgcacagca gccaccctgc ctggcaacag 3550

 agaccccaag acctacacag tgaaccctac tgccccaaag gcgttctcca 3600

 ggtgacttgt gaaaacagac ctccggggaa gtgatttatt gggggtgtac 3650

 actgggggca atatggttta gcactgaatt caatttgtcc ttaggtctat 3700

 gagtgagtcc gatcttttct tgtgaaaggt tttgggcatc gtacaaccca 3750

 ctctgcctag aaggtgtgga ggactcacca cgggcagggt cgccctggcc 3800

 cacagcacgt gagcctgcac tcactgcggc ctttgtaaca aaaccagttg 3850

 tggtcctcag catttgaagc agctgcatac ttcagagtaa actatttttc 3900

 attatttagt tttgtcacaa gaaatcgacc attgtactac tctcacttac 3950

 agcagttaaa cagcatagaa ctaaaaacct gtctgcattt ccattttttc 4000

 tttctgtatg gttgtgggtt ttaggacata gggggttagg agaaggggtt 4050

 tcttgatcat gtcatgaatt ctcctttgtc ctgtttctcc tgtttcattt 4100

 ctcctccgcc tgctgtatat tacctgagct ggtgttgtat cttcaagtcc 4150

 atatgcgtat ttgcagacct ttcctgttcc cactcttgtt ggctcttctg 4200

 atttatgcac agatggttcc cagcatgtgt ccagtgcttc atggatggga 4250

 ccatcccagc aactaatcag acttcctgcc agtgtcctaa cccccagggc 4300

 accctgttca accatattta aaaattggaa tttgtataaa gttgcttcca 4350

 agttttataa tgcatcattt tacatctttt gtaattaaaa gcatcacaat 4400

 gaggttgtct ctgcaaaaaa aaaaaaaaaa a 4431

<210> 3264
<211> 319
<212> PRT
<213> Homo sapien

<400> 3264
 Met Ser Val Gly Asn Ser Val Asn Asn Ile Pro Ala Ala Met Thr
   1               5                  10                  15

 His Leu Gly Ile Arg Ser Ser Ser Gly Leu Gln Ser Ser Arg Ser
                  20                  25                  30

 Asn Pro Ser Ile Gln Ala Thr Leu Asn Lys Thr Val Leu Ser Ser
                  35                  40                  45

 Ser Leu Asn Asn His Pro Gln Thr Ser Val Pro Asn Ala Ser Ala
                  50                  55                  60

 Leu His Pro Ser Leu Arg Leu Phe Ser Leu Ser Asn Pro Ser Leu
                  65                  70                  75

 Ser Thr Thr Asn Leu Ser Gly Pro Ser Arg Arg Arg Gln Pro Pro
                  80                  85                  90

 Val Ser Pro Leu Thr Leu Ser Pro Gly Pro Glu Ala His Gln Gly
                  95                 100                 105

 Phe Ser Arg Gln Leu Ser Ser Thr Ser Pro Leu Ala Pro Tyr Pro
                 110                 115                 120

 Thr Ser Gln Met Val Ser Ser Asp Arg Ser Gln Leu Ser Phe Leu
                 125                 130                 135

 Pro Thr Glu Ala Gln Ala Gln Val Ser Pro Pro Pro Pro Tyr Pro
                 140                 145                 150

 Ala Pro Gln Glu Leu Thr Gln Pro Leu Leu Gln Gln Pro Arg Ala
                 155                 160                 165

 Pro Glu Ala Pro Ala Gln Gln Pro Gln Ala Ala Ser Ser Leu Pro
                 170                 175                 180

 Gln Ser Asp Phe Gln Leu Leu Pro Ala Gln Gly Ser Ser Leu Thr
                 185                 190                 195

 Asn Phe Phe Pro Asp Val Gly Phe Asp Gln Gln Ser Met Arg Pro
                 200                 205                 210

 Gly Pro Ala Phe Pro Gln Gln Val Pro Leu Val Gln Gln Gly Ser
                 215                 220                 225

 Arg Glu Leu Gln Asp Ser Phe His Leu Arg Pro Ser Pro Tyr Ser
                 230                 235                 240

 Asn Cys Gly Ser Leu Ser Asn Thr Ile Leu Pro Asp Ser Ser Thr
                 245                 250                 255

 Ser Leu Phe Lys Asp Leu Asn Ser Ala Leu Ala Gly Leu Pro Glu
                 260                 265                 270

 Val Ser Leu Asn Val Asp Thr Pro Phe Pro Leu Glu Glu Glu Leu
                 275                 280                 285

 Gln Ile Glu Pro Leu Ser Leu Asp Gly Leu Asn Met Leu Ser Asp
                 290                 295                 300

 Ser Ser Met Gly Leu Leu Asp Pro Ser Val Glu Glu Thr Phe Arg
                 305                 310                 315

 Ala Asp Arg Leu


<210> 3265
<211> 3325
<212> DNA
<213> Homo sapien

<400> 3265
 cttacggcag tctcgcggga tttccccctc tcgcgggaat tatttgaacg 50

 ttcgagcggt aaatactccc tggggctgtc atagaagact cctcggagag 100

 cgctgcctct gggttggcgg gctggcaggc tgtagccgag cgcgggcagg 150

 actcgtcccg gcagggttcc agagccatgg gagcggaaag gaggctgctg 200

 tcgattaagg aggcctttcg gctggcgcag cagccgcacc agaaccaggc 250

 gaagctggtg gtggcgctga gccgcaccta ccgcacgatg gatgataaga 300

 cagtttttca tgaggagttc attcattacc ttaaatatgt tatggtggtc 350

 tataaacgtg aaccagctgt ggagagggta atagaatttg cagcaaagtt 400

 tgttacctca tttcaccaat cagatatgga agatgatgag gaagaggaag 450

 atggtggcct tttaaattat ttgtttactt ttctcttaaa gtctcatgaa 500

 gcaaacagca atgcagtgag atttagagtg tgcctgctca taaacaagct 550

 tttgggaagt atgccagaaa atgctcagat tgatgatgat gtgtttgata 600

 aaattaataa agccatgctt attagattga aagataagat tccaaatgtg 650

 agaatacagg cagttctggc gctttcacga cttcaggatc ccaaggatga 700

 tgaatgccca gtggttaatg catatgctac tttgattgaa aatgattcaa 750

 atccagaagt tagacgggca gtgttatcat gtattgcacc atcagcaaag 800

 actttgccaa aaattgtagg gcgcaccaag gatgtgaaag aggctgtcag 850

 aaagctggct tatcaggttt tagctgaaaa ggttcatatg agagctatgt 900

 ccattgctca gagagtaatg ctccttcaac aaggtcttaa tgacagatca 950

 gatgctgtga aacaagctat gcagaagcat cttcttcaag gctggttacg 1000

 gttctctgaa ggaaatatct tagagttgct ccatcggttg gatgtagaaa 1050

 attcttctga agtggcagtc tctgttctca atgccttgtt ttcaataact 1100

 cctctcagtg aactggtggg actctgtaaa aacaatgatg gcaggaaatt 1150

 gattccagtg gaaacattaa ctcctgaaat tgctttgtat tggtgtgccc 1200

 tttgtgaata tttgaaatca aaaggagatg aaggtgaaga atttttagag 1250

 cagattttgc cagagcctgt agtatatgca gactatttat tgagttacat 1300

 ccagagcatt ccagttgtta atgaagaaca cagaggtgat ttttcctata 1350

 ttggaaattt gatgacaaaa gaattcatag gtcaacaatt gattctaatt 1400

 attaagtctt tggataccag tgaagaagga ggaagaaaaa aactgctggc 1450

 tgttttacag gagattctta ttttacccac aatcccaata tccctggttt 1500

 cttttcttgt tgaaagacta ctccacatca ttatagatga taataagaga 1550

 acacaaattg ttacagaaat tatctcagag attcgggcgc ccattgttac 1600

 tgttggtgtt aataacgatc cagctgatgt aagaaagaaa gaactcaaga 1650

 tggctgaaat aaaagttaag cttatcgaag ccaaagaagc tttggaaaat 1700

 tgcattacct tacaggattt taatcgggca tcagaattaa aagaagaaat 1750

 aaaagcatta gaagatgcca gaataaacct tttgaaagag acagagcaac 1800

 ttgaaattaa agaagtccac atagagaaga atgatgctga aacattgcag 1850

 aaatgtctta ttttatgcta tgaactgttg aagcagatgt ccatttcaac 1900

 aggcttaagt gcaaccatga atggaatcat cgaatctttg attcttcctg 1950

 gaataataag tattcatcct gttgtaagaa acctggctgt tttatgcttg 2000

 ggatgctgtg gactacagaa tcaggatttt gcaaggaaac acttcgtatt 2050

 actattgcag gttttgcaaa ttgatgatgt cacaataaaa ataagtgctt 2100

 taaaggcaat ctttgaccaa ctgatgacgt tcgggattga accatttaaa 2150

 actaaaaaaa tcaaaacact tcattgtgaa ggtacagaaa taaacagtga 2200

 tgatgagcaa gaatcaaaag aagttgaaga gactgctaca gctaagaatg 2250

 ttctgaaact cctttctgat ttcttagata gtgaggtatc tgaacttagg 2300

 actggagctg cagaaggact agccaagctg atgttctctg ggcttttggt 2350

 cagcagcagg attctttctc gtcttatttt gttatggtac aatcctgtga 2400

 ctgaagagga tgttcaactt cgacattgcc taggcgtgtt cttccccgtg 2450

 tttgcttatg caagcaggac taatcaggaa tgctttgaag aagcttttct 2500

 tccaaccctg caaacactgg ccaatgcccc tgcatcttct cctttagctg 2550

 aaattgatat cacaaatgtt gctgagttac ttgtagattt gacaagacca 2600

 agtggattaa atcctcaggc caagacttcc caagattatc aggccttaac 2650

 agtacatgac aatttggcta tgaaaatttg caatgagatc ttaacaagtc 2700

 cgtgctcgcc agaaattcga gtctatacaa aagccttgag ttctttagaa 2750

 ctcagtagcc atcttgcaaa agatcttctg gttctattga atgagattct 2800

 ggagcaagta aaagatagga catgtctgag agctttggag aaaatcaaga 2850

 ttcagttaga aaaaggaaat aaagaatttg gtgaccaagc tgaagcagca 2900

 caggatgcca ccttgactac aactactttc caaaatgaag atgaaaagaa 2950

 taaagaagta tatatgactc cactcagggg tgtaaaagca acccaagcat 3000

 caaagtctac tcagctaaag actaacagag gacagagaaa agtgacagtt 3050

 tcagctagga cgaacaggag gtgtcagact gctgaagccg actctgaaag 3100

 tgatcatgaa gttccagaac cagaatcaga aatgaagatg agactaccaa 3150

 gacgagccaa aaccgcagca ctagaaaaaa gtaaacttaa ccttgcccaa 3200

 tttctcaatg aagatctaag ttaggaaaga cgatggaggt ggaatccttt 3250

 aagattatgt ccagttattt gctttaataa agaagaagtt acccttgtca 3300

 aaatcagaga aaaaaaaaaa aaaaa 3325

<210> 3266
<211> 1015
<212> PRT
<213> Homo sapien

<400> 3266
 Met Gly Ala Glu Arg Arg Leu Leu Ser Ile Lys Glu Ala Phe Arg
   1               5                  10                  15

 Leu Ala Gln Gln Pro His Gln Asn Gln Ala Lys Leu Val Val Ala
                  20                  25                  30

 Leu Ser Arg Thr Tyr Arg Thr Met Asp Asp Lys Thr Val Phe His
                  35                  40                  45

 Glu Glu Phe Ile His Tyr Leu Lys Tyr Val Met Val Val Tyr Lys
                  50                  55                  60

 Arg Glu Pro Ala Val Glu Arg Val Ile Glu Phe Ala Ala Lys Phe
                  65                  70                  75

 Val Thr Ser Phe His Gln Ser Asp Met Glu Asp Asp Glu Glu Glu
                  80                  85                  90

 Glu Asp Gly Gly Leu Leu Asn Tyr Leu Phe Thr Phe Leu Leu Lys
                  95                 100                 105

 Ser His Glu Ala Asn Ser Asn Ala Val Arg Phe Arg Val Cys Leu
                 110                 115                 120

 Leu Ile Asn Lys Leu Leu Gly Ser Met Pro Glu Asn Ala Gln Ile
                 125                 130                 135

 Asp Asp Asp Val Phe Asp Lys Ile Asn Lys Ala Met Leu Ile Arg
                 140                 145                 150

 Leu Lys Asp Lys Ile Pro Asn Val Arg Ile Gln Ala Val Leu Ala
                 155                 160                 165

 Leu Ser Arg Leu Gln Asp Pro Lys Asp Asp Glu Cys Pro Val Val
                 170                 175                 180

 Asn Ala Tyr Ala Thr Leu Ile Glu Asn Asp Ser Asn Pro Glu Val
                 185                 190                 195

 Arg Arg Ala Val Leu Ser Cys Ile Ala Pro Ser Ala Lys Thr Leu
                 200                 205                 210

 Pro Lys Ile Val Gly Arg Thr Lys Asp Val Lys Glu Ala Val Arg
                 215                 220                 225

 Lys Leu Ala Tyr Gln Val Leu Ala Glu Lys Val His Met Arg Ala
                 230                 235                 240

 Met Ser Ile Ala Gln Arg Val Met Leu Leu Gln Gln Gly Leu Asn
                 245                 250                 255

 Asp Arg Ser Asp Ala Val Lys Gln Ala Met Gln Lys His Leu Leu
                 260                 265                 270

 Gln Gly Trp Leu Arg Phe Ser Glu Gly Asn Ile Leu Glu Leu Leu
                 275                 280                 285

 His Arg Leu Asp Val Glu Asn Ser Ser Glu Val Ala Val Ser Val
                 290                 295                 300

 Leu Asn Ala Leu Phe Ser Ile Thr Pro Leu Ser Glu Leu Val Gly
                 305                 310                 315

 Leu Cys Lys Asn Asn Asp Gly Arg Lys Leu Ile Pro Val Glu Thr
                 320                 325                 330

 Leu Thr Pro Glu Ile Ala Leu Tyr Trp Cys Ala Leu Cys Glu Tyr
                 335                 340                 345

 Leu Lys Ser Lys Gly Asp Glu Gly Glu Glu Phe Leu Glu Gln Ile
                 350                 355                 360

 Leu Pro Glu Pro Val Val Tyr Ala Asp Tyr Leu Leu Ser Tyr Ile
                 365                 370                 375

 Gln Ser Ile Pro Val Val Asn Glu Glu His Arg Gly Asp Phe Ser
                 380                 385                 390

 Tyr Ile Gly Asn Leu Met Thr Lys Glu Phe Ile Gly Gln Gln Leu
                 395                 400                 405

 Ile Leu Ile Ile Lys Ser Leu Asp Thr Ser Glu Glu Gly Gly Arg
                 410                 415                 420

 Lys Lys Leu Leu Ala Val Leu Gln Glu Ile Leu Ile Leu Pro Thr
                 425                 430                 435

 Ile Pro Ile Ser Leu Val Ser Phe Leu Val Glu Arg Leu Leu His
                 440                 445                 450

 Ile Ile Ile Asp Asp Asn Lys Arg Thr Gln Ile Val Thr Glu Ile
                 455                 460                 465

 Ile Ser Glu Ile Arg Ala Pro Ile Val Thr Val Gly Val Asn Asn
                 470                 475                 480

 Asp Pro Ala Asp Val Arg Lys Lys Glu Leu Lys Met Ala Glu Ile
                 485                 490                 495

 Lys Val Lys Leu Ile Glu Ala Lys Glu Ala Leu Glu Asn Cys Ile
                 500                 505                 510

 Thr Leu Gln Asp Phe Asn Arg Ala Ser Glu Leu Lys Glu Glu Ile
                 515                 520                 525

 Lys Ala Leu Glu Asp Ala Arg Ile Asn Leu Leu Lys Glu Thr Glu
                 530                 535                 540

 Gln Leu Glu Ile Lys Glu Val His Ile Glu Lys Asn Asp Ala Glu
                 545                 550                 555

 Thr Leu Gln Lys Cys Leu Ile Leu Cys Tyr Glu Leu Leu Lys Gln
                 560                 565                 570

 Met Ser Ile Ser Thr Gly Leu Ser Ala Thr Met Asn Gly Ile Ile
                 575                 580                 585

 Glu Ser Leu Ile Leu Pro Gly Ile Ile Ser Ile His Pro Val Val
                 590                 595                 600

 Arg Asn Leu Ala Val Leu Cys Leu Gly Cys Cys Gly Leu Gln Asn
                 605                 610                 615

 Gln Asp Phe Ala Arg Lys His Phe Val Leu Leu Leu Gln Val Leu
                 620                 625                 630

 Gln Ile Asp Asp Val Thr Ile Lys Ile Ser Ala Leu Lys Ala Ile
                 635                 640                 645

 Phe Asp Gln Leu Met Thr Phe Gly Ile Glu Pro Phe Lys Thr Lys
                 650                 655                 660

 Lys Ile Lys Thr Leu His Cys Glu Gly Thr Glu Ile Asn Ser Asp
                 665                 670                 675

 Asp Glu Gln Glu Ser Lys Glu Val Glu Glu Thr Ala Thr Ala Lys
                 680                 685                 690

 Asn Val Leu Lys Leu Leu Ser Asp Phe Leu Asp Ser Glu Val Ser
                 695                 700                 705

 Glu Leu Arg Thr Gly Ala Ala Glu Gly Leu Ala Lys Leu Met Phe
                 710                 715                 720

 Ser Gly Leu Leu Val Ser Ser Arg Ile Leu Ser Arg Leu Ile Leu
                 725                 730                 735

 Leu Trp Tyr Asn Pro Val Thr Glu Glu Asp Val Gln Leu Arg His
                 740                 745                 750

 Cys Leu Gly Val Phe Phe Pro Val Phe Ala Tyr Ala Ser Arg Thr
                 755                 760                 765

 Asn Gln Glu Cys Phe Glu Glu Ala Phe Leu Pro Thr Leu Gln Thr
                 770                 775                 780

 Leu Ala Asn Ala Pro Ala Ser Ser Pro Leu Ala Glu Ile Asp Ile
                 785                 790                 795

 Thr Asn Val Ala Glu Leu Leu Val Asp Leu Thr Arg Pro Ser Gly
                 800                 805                 810

 Leu Asn Pro Gln Ala Lys Thr Ser Gln Asp Tyr Gln Ala Leu Thr
                 815                 820                 825

 Val His Asp Asn Leu Ala Met Lys Ile Cys Asn Glu Ile Leu Thr
                 830                 835                 840

 Ser Pro Cys Ser Pro Glu Ile Arg Val Tyr Thr Lys Ala Leu Ser
                 845                 850                 855

 Ser Leu Glu Leu Ser Ser His Leu Ala Lys Asp Leu Leu Val Leu
                 860                 865                 870

 Leu Asn Glu Ile Leu Glu Gln Val Lys Asp Arg Thr Cys Leu Arg
                 875                 880                 885

 Ala Leu Glu Lys Ile Lys Ile Gln Leu Glu Lys Gly Asn Lys Glu
                 890                 895                 900

 Phe Gly Asp Gln Ala Glu Ala Ala Gln Asp Ala Thr Leu Thr Thr
                 905                 910                 915

 Thr Thr Phe Gln Asn Glu Asp Glu Lys Asn Lys Glu Val Tyr Met
                 920                 925                 930

 Thr Pro Leu Arg Gly Val Lys Ala Thr Gln Ala Ser Lys Ser Thr
                 935                 940                 945

 Gln Leu Lys Thr Asn Arg Gly Gln Arg Lys Val Thr Val Ser Ala
                 950                 955                 960

 Arg Thr Asn Arg Arg Cys Gln Thr Ala Glu Ala Asp Ser Glu Ser
                 965                 970                 975

 Asp His Glu Val Pro Glu Pro Glu Ser Glu Met Lys Met Arg Leu
                 980                 985                 990

 Pro Arg Arg Ala Lys Thr Ala Ala Leu Glu Lys Ser Lys Leu Asn
                 995                1000                1005

 Leu Ala Gln Phe Leu Asn Glu Asp Leu Ser
                1010                1015

<210> 3267
<211> 1812
<212> DNA
<213> Homo sapien

<400> 3267
 ggcacgaggg agaggtcagg ggtcagcagg agtgaggctg gggcgtccag 50

 gtccgagagg tcaggggtca gctggagagg ggctggggcg ccggtttccc 100

 ggaggtcagg ggtcagaagg aacagggctg cagcgtcagg gtccgagagg 150

 ttaggggtcg gcagaggcgg agctggggca ctgggggtca ggggtcgggg 200

 atcagggcgg ggtcgggtgc actggtagcc tgcgcatggg cctccagctt 250

 cgcgcgctgt tgggagcctt cggacggtgg accctgcgcc tgggaccgcg 300

 tccgtcctgc tcgccgcgca tggccgggaa cgcggagccg ccgcccgccg 350

 gagccgcatg cccccaggac cggaggtcct gcagcggccg ggccgggggc 400

 gaccgcgtct gggaggacgg agaacatccg gcgaagaagc tcaagagcgg 450

 tggcgacgag gagcggcgcg agaagccgcc caagcggaag atcgtgctgc 500

 tcatggccta ttcgggcaag ggctaccacg gcatgcagag gaatgtcggg 550

 tcctcacaat tcaaaacaat tgaagatgac ttggtgtccg ccctcgtccg 600

 gtcaggctgt attcctgaaa atcatggtga ggacatgagg aaaatgtcct 650

 tccagcgctg cgcccggaca gacaagggtg tgtccgcagc cggccaggtg 700

 gtatccctga aggtgtggct gattgacgac attctagaaa agatcaacag 750

 ccaccttccc tctcacattc ggattctggg actgaagcgg gtcacgggcg 800

 ggtttaactc caagaacaga tgtgatgcca ggacctattg ctacctgctg 850

 cccacgtttg cctttgcgca caaggaccgg gacgttcagg atgagaccta 900

 ccgcctgagc gccgagacgc tgcagcaggt caacaggctc ctggcctgct 950

 acaagggcac gcacaacttc cacaatttca cctcgcagaa ggggccgcag 1000

 gatcccagtg cctgccgcta catcctggag atgtactgcg aggaaccctt 1050

 tgtgcgggag ggcctggagt ttgcggtgat cagggtgaag ggccagagct 1100

 tcatgatgca tcagatccgg aagatggtcg gcctggtggt ggccattgtg 1150

 aagggttatg cccctgagag cgtgctggag cgcagctggg gcacagagaa 1200

 ggtggacgtg cccaaggcgc ccggactcgg cctggtcctg gagagggtgc 1250

 acttcgagaa gtacaaccag cgctttggca acgatgggct gcatgagccg 1300

 ctggactggg cgcaggagga aggaaaggtc gcagccttca aggaggagca 1350

 catctacccc accatcatcg gcaccgagcg ggacgaacgc tccatggccc 1400

 agtggctgag caccttgccc atccacaact tcagtgccac cgctctcacg 1450

 gcaggtggca cgggcgccaa ggtgcccagt cccctggaag gcagtgaagg 1500

 ggacggagac actgactgag gcgatgggag ctgcccacca gagtgcctct 1550

 gagcagctca cagtgtgtgc ccagatgtgc cacccctgtg ggcagcaaga 1600

 agctgggatc gctgcagcca tgttttcccg gccatgccgg cgttgtaacc 1650

 tcaggacctt cccttgtagg aacagccttt ctcgaatctg ttttcagctc 1700

 ttgcattgca tagatgaacc tcagcatgta aagaactatt tttttaaaga 1750

 agtgattttc ttattaaaca agtacaaatt ttgcttagtc aaaaaaaaaa 1800

 aaaaaaaaaa aa 1812

<210> 3268
<211> 399
<212> PRT
<213> Homo sapien

<400> 3268
 Met Ala Gly Asn Ala Glu Pro Pro Pro Ala Gly Ala Ala Cys Pro
   1               5                  10                  15

 Gln Asp Arg Arg Ser Cys Ser Gly Arg Ala Gly Gly Asp Arg Val
                  20                  25                  30

 Trp Glu Asp Gly Glu His Pro Ala Lys Lys Leu Lys Ser Gly Gly
                  35                  40                  45

 Asp Glu Glu Arg Arg Glu Lys Pro Pro Lys Arg Lys Ile Val Leu
                  50                  55                  60

 Leu Met Ala Tyr Ser Gly Lys Gly Tyr His Gly Met Gln Arg Asn
                  65                  70                  75

 Val Gly Ser Ser Gln Phe Lys Thr Ile Glu Asp Asp Leu Val Ser
                  80                  85                  90

 Ala Leu Val Arg Ser Gly Cys Ile Pro Glu Asn His Gly Glu Asp
                  95                 100                 105

 Met Arg Lys Met Ser Phe Gln Arg Cys Ala Arg Thr Asp Lys Gly
                 110                 115                 120

 Val Ser Ala Ala Gly Gln Val Val Ser Leu Lys Val Trp Leu Ile
                 125                 130                 135

 Asp Asp Ile Leu Glu Lys Ile Asn Ser His Leu Pro Ser His Ile
                 140                 145                 150

 Arg Ile Leu Gly Leu Lys Arg Val Thr Gly Gly Phe Asn Ser Lys
                 155                 160                 165

 Asn Arg Cys Asp Ala Arg Thr Tyr Cys Tyr Leu Leu Pro Thr Phe
                 170                 175                 180

 Ala Phe Ala His Lys Asp Arg Asp Val Gln Asp Glu Thr Tyr Arg
                 185                 190                 195

 Leu Ser Ala Glu Thr Leu Gln Gln Val Asn Arg Leu Leu Ala Cys
                 200                 205                 210

 Tyr Lys Gly Thr His Asn Phe His Asn Phe Thr Ser Gln Lys Gly
                 215                 220                 225

 Pro Gln Asp Pro Ser Ala Cys Arg Tyr Ile Leu Glu Met Tyr Cys
                 230                 235                 240

 Glu Glu Pro Phe Val Arg Glu Gly Leu Glu Phe Ala Val Ile Arg
                 245                 250                 255

 Val Lys Gly Gln Ser Phe Met Met His Gln Ile Arg Lys Met Val
                 260                 265                 270

 Gly Leu Val Val Ala Ile Val Lys Gly Tyr Ala Pro Glu Ser Val
                 275                 280                 285

 Leu Glu Arg Ser Trp Gly Thr Glu Lys Val Asp Val Pro Lys Ala
                 290                 295                 300

 Pro Gly Leu Gly Leu Val Leu Glu Arg Val His Phe Glu Lys Tyr
                 305                 310                 315

 Asn Gln Arg Phe Gly Asn Asp Gly Leu His Glu Pro Leu Asp Trp
                 320                 325                 330

 Ala Gln Glu Glu Gly Lys Val Ala Ala Phe Lys Glu Glu His Ile
                 335                 340                 345

 Tyr Pro Thr Ile Ile Gly Thr Glu Arg Asp Glu Arg Ser Met Ala
                 350                 355                 360

 Gln Trp Leu Ser Thr Leu Pro Ile His Asn Phe Ser Ala Thr Ala
                 365                 370                 375

 Leu Thr Ala Gly Gly Thr Gly Ala Lys Val Pro Ser Pro Leu Glu
                 380                 385                 390

 Gly Ser Glu Gly Asp Gly Asp Thr Asp
                 395

<210> 3269
<211> 1932
<212> DNA
<213> Homo sapien

<400> 3269
 ccggactgcg gaaggatgga gctggccgcc ggaagcttct cggaggagca 50

 gttctgggag gcctgcgccg agctccagca gcccgctctg gccggggccg 100

 actggcagct cctagtggag acctcgggca tcagcatcta ccggctgctg 150

 gacaagaaga ctggacttca tgagtataaa gtctttggtg ttctggagga 200

 ctgctcacca actctactgg cagacatcta tatggactca gattacagaa 250

 aacaatggga ccagtatgtt aaagaactct atgaacaaga atgcaacgga 300

 gagactgtgg tctactggga agtgaagtac ccttttccca tgtccaacag 350

 agactatgtc taccttcggc agcggcgaga cctggacatg gaagggagga 400

 agatccatgt gatcctggcc cggagcacct ccatgcctca gcttggcgag 450

 aggtctgggg tgatccgggt gaagcaatac aagcagagcc tggcgattga 500

 gagtgacggc aagaagggga gcaaagtttt catgtattac ttcgataacc 550

 cgggtggcca aattccgtcc tggctcatta actgggccgc caagaatgga 600

 gttcctaact tcttgaaaga catggcaaga gcctgtcaga actacctcaa 650

 gaaaacctaa gaaagagaac tgggaacatt gcatccatgg gttgatgtct 700

 ctggaagtgc aaccacccaa tgtctctgga agtgccacct ggaagtgcca 750

 cctggaagtg tctctggaag agcacccacc actgttcagc cttcccctgc 800

 tgtttctgtc ttcagaggcc tacacactac cacatccttt ctaagcatgt 850

 ttgcctgaca tccagctcac tcgtctgctt cctttctcgc tccccccatc 900

 ctgggctggg ctgccttctt ctacagttca atatggggca gactagggaa 950

 acctttgctt gcttactatt aggaggggaa gtcttcagta gggaacacga 1000

 tcattccatt gtgcaatttt acggggatgg gtgggcggag ggacacaaca 1050

 aaatttaaga atgactattt gggcgggctg gctcttttgc agcttgtgat 1100

 ttcttccagc ttgggagggg ctgctggaag tggcatttcg ttcagagctg 1150

 actttcagtg cacccaaact ggatgacgtg ccaatgtcca tttgccttat 1200

 gctttgtgga gctgattagg ctgggatttg aggtgataat ccagtaagtc 1250

 tttcctcgtt cctacttgtg gaggatcagt agctgttatg atgccagacc 1300

 atttggagaa gtatcagagg cctgaccgga cacataatac gacaaccaca 1350

 tttttcctca tcatccatga ggaaatggat gatttctctt ttccatatgt 1400

 cactggggga aaggctgcct gtacctctca agctttgcat tttactggaa 1450

 actgaggcgt caagatggct gtggcagcta gcaaaagcaa agatgctttg 1500

 tgcatagcct tgtgaaaaag tatctttcta tgcaataaga tgaattttcc 1550

 tcccagaata tttagaaatg tagaagggat aacagttcac agccaggtaa 1600

 aatttaactg gtggcttaat gactctgcac ctttttctca ggaattctgc 1650

 ctaagttgtc tgccttttct accaccaaaa agacttttag ttttctatgc 1700

 tttctcctga attttggtag ggtaagtatt tctatgtcaa aggcacagcc 1750

 ttgatgatct cagggaaaaa ttttaatcac tgtgtataat gatactgaac 1800

 cttgattaat aacagaaatt caggatgtaa agccacagaa tgggatttat 1850

 taatgtggga tacctcagac tgtttgtttt ctttctggga agaaaagtgt 1900

 gttctataat gaataaatat agagtggttt tt 1932

<210> 3270
<211> 214
<212> PRT
<213> Homo sapien

<400> 3270
 Met Glu Leu Ala Ala Gly Ser Phe Ser Glu Glu Gln Phe Trp Glu
   1               5                  10                  15

 Ala Cys Ala Glu Leu Gln Gln Pro Ala Leu Ala Gly Ala Asp Trp
                  20                  25                  30

 Gln Leu Leu Val Glu Thr Ser Gly Ile Ser Ile Tyr Arg Leu Leu
                  35                  40                  45

 Asp Lys Lys Thr Gly Leu His Glu Tyr Lys Val Phe Gly Val Leu
                  50                  55                  60

 Glu Asp Cys Ser Pro Thr Leu Leu Ala Asp Ile Tyr Met Asp Ser
                  65                  70                  75

 Asp Tyr Arg Lys Gln Trp Asp Gln Tyr Val Lys Glu Leu Tyr Glu
                  80                  85                  90

 Gln Glu Cys Asn Gly Glu Thr Val Val Tyr Trp Glu Val Lys Tyr
                  95                 100                 105

 Pro Phe Pro Met Ser Asn Arg Asp Tyr Val Tyr Leu Arg Gln Arg
                 110                 115                 120

 Arg Asp Leu Asp Met Glu Gly Arg Lys Ile His Val Ile Leu Ala
                 125                 130                 135

 Arg Ser Thr Ser Met Pro Gln Leu Gly Glu Arg Ser Gly Val Ile
                 140                 145                 150

 Arg Val Lys Gln Tyr Lys Gln Ser Leu Ala Ile Glu Ser Asp Gly
                 155                 160                 165

 Lys Lys Gly Ser Lys Val Phe Met Tyr Tyr Phe Asp Asn Pro Gly
                 170                 175                 180

 Gly Gln Ile Pro Ser Trp Leu Ile Asn Trp Ala Ala Lys Asn Gly
                 185                 190                 195

 Val Pro Asn Phe Leu Lys Asp Met Ala Arg Ala Cys Gln Asn Tyr
                 200                 205                 210

 Leu Lys Lys Thr


<210> 3271
<211> 2927
<212> DNA
<213> Homo sapien

<400> 3271
 cttcgcgcac ctcatggaat cccttctgca gcacctggat cgcttttccg 50

 agcttctggc ggtctcaagc actacctacg tcagcacctg ggaccccgcc 100

 accgtgcgcc gggccttgca gtgggcgcgc tacctgcgcc acatccatcg 150

 gcgctttggt cggcatggcc ccattcgcac ggctctggag cggcggctgc 200

 acaaccagtg gaggcaagag ggcggctttg ggcggggtcc agttccggga 250

 ttagcgaact tccaggccct cggtcactgt gacgtcctgc tctctctgcg 300

 cctgctggag aaccgggccc tcggggatgc agctcgttac cacctggtgc 350

 agcaactctt tcccggcccg ggcgtccggg acgccgatga ggagacactc 400

 caagagagcc tggcccgcct tgcccgccgg cggtctgcgg tgcacatgct 450

 gcgcttcaat ggctatagag agaacccaaa tctccaggag gactctctga 500

 tgaagaccca ggcggagctg ctgctggagc gtctgcagga ggtggggaag 550

 gccgaagcgg agcgtcccgc caggtttctc agcagcctgt gggagcgctt 600

 gcctcagaac aacttcctga aggtgatagc ggtggcgctg ttgcagccgc 650

 ctttgtctcg tcggccccaa gaagagttgg aacccggcat ccacaaatca 700

 cctggagagg ggagccaagt gctagtccac tggcttctgg ggaattcgga 750

 agtctttgct gccttttgtc gcgccctccc agccgggctt ttgactttag 800

 tgactagccg ccacccagcg ctgtctcctg tctatctggg tctgctaaca 850

 gactggggtc aacgtttgca ctatgacctt cagaaaggca tttgggttgg 900

 aactgagtcc caagatgtgc cctgggagga gttgcacaat aggtttcaaa 950

 gcctctgtca ggcccctcca cctctgaaag ataaagttct aactgccctg 1000

 gagacctgta aagcgcagga tggagatttt gaagtacctg gtcttagcat 1050

 ctggacagac ctcttattag ctcttcgtag tggtgcattt aggaaaagac 1100

 aagttttggg tctcagcgca ggcctcagtt ctgtataggc aatgctgtgt 1150

 tattacttga atatagaata tatagtttac aaaatgaaaa ttacaatgtt 1200

 ctcaccaaat atatgccttc gtgtgtccaa agtataatta ttttagatgc 1250

 taattttgaa tagtttatta aacagttata aatatgcaaa gtagctggca 1300

 tgtagtgtca cggattttct ggatagagga agtgattgga agtattccac 1350

 ttaaagccat ggaattagca atagtttgct ttttaataga aggcccattt 1400

 gtaagaatgt tgaaaatatg tgtaccgttt aaagaaaaag cagctttaaa 1450

 gtgacaaaca aaataccctt tttcttttag tatggtttat ttttctaggt 1500

 tttctgtccc tccctcagta gtgaagagtt ttctttattc ctggcagtgt 1550

 caggaatatt ggtttgaaaa gctgttggcc tatctggagt ttggccttgt 1600

 taacctagta ttctaaccag ttaaccagcc ttagtatgca ttaaaattgt 1650

 attgttcaga aagtttgttt ctcattttct gcaaattctt actttgaaaa 1700

 tgaatcacca catagtatgt ccctttaaag cattgacgca cagacaaatg 1750

 tttaaagcac agtaaataca aatatatgcc tttggatact aaattaatgc 1800

 ttgatgataa aagaatcaaa cttttttttt tttgagatgg agtctcgctc 1850

 tgtcacccag tctggagtgc agtggtgtga tcactgctca gtgcaacctc 1900

 tgcctcccag gatcaagcaa ttctgactca gcctcccaag tagctgggat 1950

 tacaggtgca ggccaccatg cccggctaat tttttgtatt tttagtagag 2000

 acggggtttc accatgctgg ccaggctggt ctcaaacacc tgaccttgtg 2050

 atccgtccgc cttggcctcc caaagtgctg ggattacagg cgtgagccac 2100

 cgcgcctggc caaaacaaca ttttaagtag aagatccagg ttttagtgca 2150

 gcttctgccg ttaactaggt taataaatca caaccttggg gccacagttg 2200

 ccttatatgt aaatgaagtg tttagaataa aatagttaaa tttccttatt 2250

 tttcccttgg tggctgccct gtggaaacag tttagaatat ttgttttgtg 2300

 tgtaggaacc tagttgtgtt agtttacctg ggtgttccac agctgatagt 2350

 gattgccttg aataaattca agggcaattt attcattttt actagggaga 2400

 tagaccttta cagcaatcaa gatatttttg tccatatcca ggttagctgg 2450

 taagaggatt tttttggaga aaaaaaatga tatttagaaa gttaatttct 2500

 aattccggaa tggaataaaa acaatatgag tagtgtaatc ttgtagaaaa 2550

 agagttgtat aatcttgtag aatttctcat tctgtggtac aacccagggg 2600

 taaactatta ttccagtagt cagtacactt ttctagataa atcttgagtg 2650

 aaaaccagca atttcttttt ccttgtggtc tgattccttt ttctaatcca 2700

 tgaaggccat cttgtagatt acatttatca ttaatgcaag aataaagaca 2750

 attcctcctg tcagttgcgt gaattttttt taagaaacaa cccagtgaag 2800

 agttctacca tagcaaggcc taatgttagc tttagcttta gaaaataaca 2850

 gtttgtgaac ttacttccct atatttgcag ctgtatctca cactatgatt 2900

 tacaataaaa ttgtaaagat tgacaat 2927

<210> 3272
<211> 374
<212> PRT
<213> Homo sapien

<400> 3272
 Met Glu Ser Leu Leu Gln His Leu Asp Arg Phe Ser Glu Leu Leu
   1               5                  10                  15

 Ala Val Ser Ser Thr Thr Tyr Val Ser Thr Trp Asp Pro Ala Thr
                  20                  25                  30

 Val Arg Arg Ala Leu Gln Trp Ala Arg Tyr Leu Arg His Ile His
                  35                  40                  45

 Arg Arg Phe Gly Arg His Gly Pro Ile Arg Thr Ala Leu Glu Arg
                  50                  55                  60

 Arg Leu His Asn Gln Trp Arg Gln Glu Gly Gly Phe Gly Arg Gly
                  65                  70                  75

 Pro Val Pro Gly Leu Ala Asn Phe Gln Ala Leu Gly His Cys Asp
                  80                  85                  90

 Val Leu Leu Ser Leu Arg Leu Leu Glu Asn Arg Ala Leu Gly Asp
                  95                 100                 105

 Ala Ala Arg Tyr His Leu Val Gln Gln Leu Phe Pro Gly Pro Gly
                 110                 115                 120

 Val Arg Asp Ala Asp Glu Glu Thr Leu Gln Glu Ser Leu Ala Arg
                 125                 130                 135

 Leu Ala Arg Arg Arg Ser Ala Val His Met Leu Arg Phe Asn Gly
                 140                 145                 150

 Tyr Arg Glu Asn Pro Asn Leu Gln Glu Asp Ser Leu Met Lys Thr
                 155                 160                 165

 Gln Ala Glu Leu Leu Leu Glu Arg Leu Gln Glu Val Gly Lys Ala
                 170                 175                 180

 Glu Ala Glu Arg Pro Ala Arg Phe Leu Ser Ser Leu Trp Glu Arg
                 185                 190                 195

 Leu Pro Gln Asn Asn Phe Leu Lys Val Ile Ala Val Ala Leu Leu
                 200                 205                 210

 Gln Pro Pro Leu Ser Arg Arg Pro Gln Glu Glu Leu Glu Pro Gly
                 215                 220                 225

 Ile His Lys Ser Pro Gly Glu Gly Ser Gln Val Leu Val His Trp
                 230                 235                 240

 Leu Leu Gly Asn Ser Glu Val Phe Ala Ala Phe Cys Arg Ala Leu
                 245                 250                 255

 Pro Ala Gly Leu Leu Thr Leu Val Thr Ser Arg His Pro Ala Leu
                 260                 265                 270

 Ser Pro Val Tyr Leu Gly Leu Leu Thr Asp Trp Gly Gln Arg Leu
                 275                 280                 285

 His Tyr Asp Leu Gln Lys Gly Ile Trp Val Gly Thr Glu Ser Gln
                 290                 295                 300

 Asp Val Pro Trp Glu Glu Leu His Asn Arg Phe Gln Ser Leu Cys
                 305                 310                 315

 Gln Ala Pro Pro Pro Leu Lys Asp Lys Val Leu Thr Ala Leu Glu
                 320                 325                 330

 Thr Cys Lys Ala Gln Asp Gly Asp Phe Glu Val Pro Gly Leu Ser
                 335                 340                 345

 Ile Trp Thr Asp Leu Leu Leu Ala Leu Arg Ser Gly Ala Phe Arg
                 350                 355                 360

 Lys Arg Gln Val Leu Gly Leu Ser Ala Gly Leu Ser Ser Val
                 365                 370

<210> 3273
<211> 1226
<212> DNA
<213> Homo sapien

<400> 3273
 gctgccgcat cccaggctaa gcgccgcgcc gaaagccgtg cggagattgg 50

 aggccgcgcg ggtccctggt ctgggccatg tctggctgtg atgctgggga 100

 gggagactgt tgttcccgga gatgcggcgc gcaggacaag gagcatccaa 150

 gatacctgat cccagaactt tgcaaacagt tttaccattt aggctgggtc 200

 actgggactg gaggaggaat tagcttgaag catggcgatg aaatctacat 250

 tgctccttca ggagtgcaaa aggaacgaat tcagcctgaa gacatgtttg 300

 tttgtgatat aaatgaaaag gacataagtg gaccttcgcc atcgaagaag 350

 ctaaaaaaaa gccagtgtac tcctcttttc atgaatgctt acacaatgag 400

 aggagcaggt gcagtgattc atacccactc taaagctgct gtgatggcca 450

 cacttctctt tccaggacgg gagtttaaaa ttacacatca agagatgata 500

 aaaggaataa agaaatgtac ttccggaggg tattatagat atgatgatat 550

 gttagtggta cccattattg agaatacacc tgaggagaag accctcaaag 600

 atagaatggc tcatgcaatg aatgaatacc cagactcctg tgcagtactg 650

 gtcagacgtc atggagtata tgtgtggggg gaaacatggg agaaggccaa 700

 aaccatgtgt gagtgttatg actatttatt tgatattgcc gtatcaatga 750

 agaaagtagg acttgatcct tcacagctcc cagttggaga aaatggaatt 800

 gtctaagcca aaagaaagtc taattatata cagagataaa gctaaacgta 850

 attattattt aaatgaaagc tattttttta aatgaattga aatttttcat 900

 gatgctacta atttgccact aaatactgca aatggtcacc ctgaatctct 950

 tctgacattg gatgttattt gcttatattc ttataatttt aaatgagggc 1000

 acagtgaaat gaaaatttta tactctatgt ttctgtttat ttttaaatcc 1050

 ttaacagcaa aatatttgcc tttaatttct tttttatata tactctcgag 1100

 agaattcctc ttaattttta aagatgctgg tgataataaa attcattaga 1150

 aaatttcctc attgtggaat gagcattctc ttgttttaat gttggtgtca 1200

 gaaaataaat atgaaacatt aagtcc 1226

<210> 3274
<211> 242
<212> PRT
<213> Homo sapien

<400> 3274
 Met Ser Gly Cys Asp Ala Gly Glu Gly Asp Cys Cys Ser Arg Arg
   1               5                  10                  15

 Cys Gly Ala Gln Asp Lys Glu His Pro Arg Tyr Leu Ile Pro Glu
                  20                  25                  30

 Leu Cys Lys Gln Phe Tyr His Leu Gly Trp Val Thr Gly Thr Gly
                  35                  40                  45

 Gly Gly Ile Ser Leu Lys His Gly Asp Glu Ile Tyr Ile Ala Pro
                  50                  55                  60

 Ser Gly Val Gln Lys Glu Arg Ile Gln Pro Glu Asp Met Phe Val
                  65                  70                  75

 Cys Asp Ile Asn Glu Lys Asp Ile Ser Gly Pro Ser Pro Ser Lys
                  80                  85                  90

 Lys Leu Lys Lys Ser Gln Cys Thr Pro Leu Phe Met Asn Ala Tyr
                  95                 100                 105

 Thr Met Arg Gly Ala Gly Ala Val Ile His Thr His Ser Lys Ala
                 110                 115                 120

 Ala Val Met Ala Thr Leu Leu Phe Pro Gly Arg Glu Phe Lys Ile
                 125                 130                 135

 Thr His Gln Glu Met Ile Lys Gly Ile Lys Lys Cys Thr Ser Gly
                 140                 145                 150

 Gly Tyr Tyr Arg Tyr Asp Asp Met Leu Val Val Pro Ile Ile Glu
                 155                 160                 165

 Asn Thr Pro Glu Glu Lys Thr Leu Lys Asp Arg Met Ala His Ala
                 170                 175                 180

 Met Asn Glu Tyr Pro Asp Ser Cys Ala Val Leu Val Arg Arg His
                 185                 190                 195

 Gly Val Tyr Val Trp Gly Glu Thr Trp Glu Lys Ala Lys Thr Met
                 200                 205                 210

 Cys Glu Cys Tyr Asp Tyr Leu Phe Asp Ile Ala Val Ser Met Lys
                 215                 220                 225

 Lys Val Gly Leu Asp Pro Ser Gln Leu Pro Val Gly Glu Asn Gly
                 230                 235                 240

 Ile Val


<210> 3275
<211> 2376
<212> DNA
<213> Homo sapien

<400> 3275
 gagactgtgg gcgcgtggtg cagtccctgg agggttctca cgctttggct 50

 gtctggactt ttaagttttt ccgctttttc aggaaggcga ccggcagcct 100

 cgggcagggg agacaggact gtatgtcaga gaagagacgg cgcttggacg 150

 ccaggaatcc tctgaagcag gagactgccc tatccagaag atgactcaag 200

 accggcctct gcttgccgtg caggaggcgc tgaagaagtg cttccccgtg 250

 gtggaggagc agcagggcct gtggcagagt gccctgcggg actgccagcc 300

 cctcctgtcc tccctcagca acctggcgga acagctgcag gccgcacaga 350

 acctgcggtt tgaggatgtg ccggcgcttc gggccttccc agatttaaaa 400

 gagcggctga ggcgtaagca gctggtggct ggtgacatcg tcctggacaa 450

 gctaggggaa aggctagcca tcctcctcaa ggtgcgagac atggtcagca 500

 gccatgtgga gcgagtgttt cagatctatg agcaacacgc agacacagtt 550

 ggcattgatg ctgtcctgca gccttcagca gtgagcccct ctgtggctga 600

 catgttggaa tggttgcagg atattgagag acattatcga aagtcgtacc 650

 tgaagagaaa gtatcttctt tcgtctatcc agtggggaga cttggcaaac 700

 atacaagctt tgcccaaggc ctgggaccga atttcaaaag acgaacacca 750

 ggatcttgta caagatatcc tattgaatgt ttccttcttc ctggaagagt 800

 aaggaagcta tgcgtatctg gagaccacgg gcaccacagt tgaagactga 850

 cattctgaac cctgatgttt ctaaagaaac gtcagtattt cagtctgaca 900

 tatttgaaac atcagtgcct tgaaccttag gactgggtct tggggaggat 950

 tagcgcctag atgtctgatt ttggagctgc agcatgccag gccgtggctg 1000

 agggtatgtg agccatgcct tgcccttttc tgaggctcag ggaagtggat 1050

 ggagctagag agacaacagg aaagacggtg ctgaagaaca tagtgtcttt 1100

 cctctattgt ggacctaaag aggtggggaa gcaaggacaa gaggcaaaga 1150

 gccacactgc ccttggcatc atccaaagca ttgtctggtt gacaccaggt 1200

 cctggttttg tgtcttttgt caatacctga atccttgaca aaagaaaaag 1250

 tggttttgat gatttaaaga aataagggtg attttgacag aaaatatatt 1300

 ttaaaaattt tgaccaattg caatagttat cctcaagcca atttccagaa 1350

 cctgccacca gggggaggtg atgcagcatg aatcattctg aatgctttgt 1400

 ctttgaagtg ctcccctatt gctgttacca tctcagagga agtaactggg 1450

 catggtgaga ctcctaaaat gacaggagtt tttttggcca aagctggcat 1500

 ctgacttgcc acattcctct gagtctggag tagccgcagg ggtgggagaa 1550

 tgccagccca gagtcagtcc atcggggtta catttccaag gtctgctgcc 1600

 ttcatctatg taatggccgt gttactttca gatctttcag cttcccagag 1650

 tgttgtggga atcttggtca ttgaatgtaa agggacttag taaagggtat 1700

 agatattttt caaaaatgaa aataactttt tttcttataa gtgataagct 1750

 tttataaaga tcataggaaa actagaaaaa atgtaaaatg tagaaaattg 1800

 taaaacaaac ttcattagag atattttgat agataccttt tcagtgtcta 1850

 tttacaaatt ttttctttta atatagatag ggtctcacta tattgcccag 1900

 ctcactcctg agctcaaggg atcctcccac catagcctcc caaaatattg 1950

 gaaatacagg catgagccac tgctcctgac caattcacaa atttttttaa 2000

 agaacaaacg tgctatcatc gatacatact gttaggttgt ctttttttaa 2050

 aaaacctaat gtaatttgtt catcttttta tatctgtaaa tatagctcaa 2100

 cacagttata ttctttttgt gaatgtatta tatctacaat ttaccttttt 2150

 tcttagattt tacatgcatt ttcccaaatc tttgtgtttg cctatctgta 2200

 aaggtaatac attctgatta caaaaaatga aaatgttaca tagaaatgta 2250

 ccgttatcca tctaccagat aactattatt aataatgtgt atttattttt 2300

 ccaggaatta aaaaacatct atcatataag tattgcaaat aaaacttaaa 2350

 aagcaaaaaa aaaaaaaaaa aaaaaa 2376

<210> 3276
<211> 203
<212> PRT
<213> Homo sapien

<400> 3276
 Met Thr Gln Asp Arg Pro Leu Leu Ala Val Gln Glu Ala Leu Lys
   1               5                  10                  15

 Lys Cys Phe Pro Val Val Glu Glu Gln Gln Gly Leu Trp Gln Ser
                  20                  25                  30

 Ala Leu Arg Asp Cys Gln Pro Leu Leu Ser Ser Leu Ser Asn Leu
                  35                  40                  45

 Ala Glu Gln Leu Gln Ala Ala Gln Asn Leu Arg Phe Glu Asp Val
                  50                  55                  60

 Pro Ala Leu Arg Ala Phe Pro Asp Leu Lys Glu Arg Leu Arg Arg
                  65                  70                  75

 Lys Gln Leu Val Ala Gly Asp Ile Val Leu Asp Lys Leu Gly Glu
                  80                  85                  90

 Arg Leu Ala Ile Leu Leu Lys Val Arg Asp Met Val Ser Ser His
                  95                 100                 105

 Val Glu Arg Val Phe Gln Ile Tyr Glu Gln His Ala Asp Thr Val
                 110                 115                 120

 Gly Ile Asp Ala Val Leu Gln Pro Ser Ala Val Ser Pro Ser Val
                 125                 130                 135

 Ala Asp Met Leu Glu Trp Leu Gln Asp Ile Glu Arg His Tyr Arg
                 140                 145                 150

 Lys Ser Tyr Leu Lys Arg Lys Tyr Leu Leu Ser Ser Ile Gln Trp
                 155                 160                 165

 Gly Asp Leu Ala Asn Ile Gln Ala Leu Pro Lys Ala Trp Asp Arg
                 170                 175                 180

 Ile Ser Lys Asp Glu His Gln Asp Leu Val Gln Asp Ile Leu Leu
                 185                 190                 195

 Asn Val Ser Phe Phe Leu Glu Glu
                 200

<210> 3277
<211> 895
<212> DNA
<213> Homo sapien

<400> 3277
 gcggccgcgt cgaccggcgc ggctggagcg cagcgccgaa gggactggca 50

 gggctgaagt gtgcgggaca gcaagccccc gaatagcccc ggctgccacc 100

 tcgcaggacc caaggccacg cgcgccgggc ccagctgagc cgcctcatga 150

 agccgcccgc ggaggacctg tcggacgcgc tgtgcgagtt tgacgcggtg 200

 ctggccgact tcgcgtcgcc cttccacgag cgccacttcc actacgagga 250

 gcacctggag cgcatgaagc ggcgcagcag cgccagtgtc agcgacagca 300

 gcggcttcag cgactcggag agtgcagatt cactttatag gaacagcttc 350

 agcttcagtg atgaaaaact gaattctcca acagactcta ccccagctct 400

 tctctctgcc actgtcactc ctcagaaagc taaattagga gacacaaaag 450

 agctagaagc cttcattgct gatcttgaca aaactttagc aagtatgtga 500

 aacaagaagt tctgggtcct ttcatcataa gggagaagct tcagaaagtt 550

 ccgaggacct gctaaaatca gctactagaa tctgctgcca gaggggacaa 600

 agacgtgcac tcaaccttct accaggccac tctcaggctc accttaaaat 650

 cagcccttga tcccatttct gggcaattta gacagtgaaa ctgactttgt 700

 ttacctgctt gcagcatatt agaacagacg atccatgcta atattgtatt 750

 ttctcttaaa acatagcttt cctgtaattt aaagtgcttt tatgaaaata 800

 tttgtaatta attatatata gttggaaata gcagtaagct ttcccattat 850

 aatatatttt tgtatacaaa taaaatttga actgaacctc gtgcc 895

<210> 3278
<211> 117
<212> PRT
<213> Homo sapien

<400> 3278
 Met Lys Pro Pro Ala Glu Asp Leu Ser Asp Ala Leu Cys Glu Phe
   1               5                  10                  15

 Asp Ala Val Leu Ala Asp Phe Ala Ser Pro Phe His Glu Arg His
                  20                  25                  30

 Phe His Tyr Glu Glu His Leu Glu Arg Met Lys Arg Arg Ser Ser
                  35                  40                  45

 Ala Ser Val Ser Asp Ser Ser Gly Phe Ser Asp Ser Glu Ser Ala
                  50                  55                  60

 Asp Ser Leu Tyr Arg Asn Ser Phe Ser Phe Ser Asp Glu Lys Leu
                  65                  70                  75

 Asn Ser Pro Thr Asp Ser Thr Pro Ala Leu Leu Ser Ala Thr Val
                  80                  85                  90

 Thr Pro Gln Lys Ala Lys Leu Gly Asp Thr Lys Glu Leu Glu Ala
                  95                 100                 105

 Phe Ile Ala Asp Leu Asp Lys Thr Leu Ala Ser Met
                 110                 115

<210> 3279
<211> 2461
<212> DNA
<213> Homo sapien

<400> 3279
 atgctgggta cgctgcgcgc catggagggc gaggacgtgg aagacgacca 50

 gctgctgcag aagctcaggg ccagtcgccg ccgcttccag aggcgcatgc 100

 agcggctgat agagaagtac aaccagccct tcgaggacac cccggtggtg 150

 caaatggcca cgctgaccta cgagacgcca cagggattga gaatttgggg 200

 tggaagacta ataaaggaaa gaaacaaagg agagatccag gactcctcca 250

 tgaagcccgc ggacaggaca gatggctccg tgcaagctgc agcctggggt 300

 cctgagcttc cctcgcaccg cacagtcctg ggagccgatt caaaaagcgg 350

 tgaggtcgat gccacgtcag accaggaaga gtcagttgct tgggccttag 400

 cacctgcagt gcctcaaagc cctttgaaaa atgaattaag aaggaaatac 450

 ttgacccaag tggatatact gctacaaggt gcagagtatt ttgagtgtgc 500

 aggtaacaga gctggaaggg atgtacgtgt gactccgctg ccttcactgg 550

 cctcacctgc cgtgcctgcc cccggatact gcagtcgtat ctccggaaag 600

 agtcctggtg acccagcgaa accagcttca tctcccagag aatgggatcc 650

 tttgcatcct tcctccacag acatggcctt agtacctaga aatgacagcc 700

 tctccctaca agagaccagt agcagcagct tcttaagcag ccagcccttt 750

 gaagatgatg acatttgcaa tgtgaccatc agtgacctgt acgcagggat 800

 gctgcactcc atgagccggc tgttgagcac aaagccatca agcatcatct 850

 ccaccaaaac gttcatcatg caaaactgga actgcaggag gaggcacaga 900

 tataagagca ggatgaacaa aacatattgc aaaggagcca gacgttctca 950

 gaggagctcc aaggagaact tcataccctg ctctgagcct gtgaaaggga 1000

 caggggcatt aagagattgc aagaacgtat tagatgtttc ttgccgtaag 1050

 acaggtttaa aattggaaaa agcttttctt gaagtcaaca gaccccaaat 1100

 ccataagtta gatccaagtt ggaaggagcg caaagtgaca ccctcgaagt 1150

 attcttcctt gatttacttc gactccagtg caacatataa tcttgatgag 1200

 gaaaatagat ttaggacatt aaaatggtta atttctcctg taaaaatagt 1250

 ttccagacca acaatacgac agggccatgg agagaaccgt cagagggaga 1300

 ttgaaatccg atttgatcag cttcatcggg aatattgcct gagtcccagg 1350

 aaccagcctc gccggatgtg cctcccggac tcctgggcca tgaacatgta 1400

 cagagggggt cctgcgagtc ctggtggcct tcagggctta gaaacccgca 1450

 ggctgagttt accttccagc aaagcaaaag caaaaagttt aagtgaggct 1500

 tttgaaaacc taggcaaaag atctctggaa gcaggtaggt gcctgcccaa 1550

 gagcgattca tcttcatcac ttccaaagac caaccccaca cacagcgcaa 1600

 ctcgcccgca gcagacatct gaccttcacg ttcagggaaa tagttctgga 1650

 atatttagaa agtcagtgtc acccagcaaa actctttcag tcccagataa 1700

 agaagtgcca ggccacggaa ggaatcgtta cgatgaaatt aaagaagaat 1750

 ttgacaagct tcatcaaaag tattgcctca aatctcctgg gcagatgaca 1800

 gtgcctttat gtattggagt gtctacagat aaagcaagta tggaagttcg 1850

 atatcaaaca gaaggcttct taggaaaatt aaatccagac cctcacttcc 1900

 agggtttcca gaagttgcca tcatcacccc tggggtgcag aaaaagtcta 1950

 ctgggctcaa ctgcaattga ggctccttca tctacatgtg ttgctcgtgc 2000

 catcacgagg gatggcacga gggaccatca gttccctgca aaaagaccca 2050

 ggctatcaga accccagggc tccggacgcc agggcaattc cctgggtgcc 2100

 tcagatgggg tggacaacac cgtcagaccg ggagaccagg gcagctcttc 2150

 acagcccaac tcagaagaga gaggagagaa cacgtcttac aggatggaag 2200

 agaaaagtga tttcatgcta gaaaaattgg aaactaaaag tgtgtagcta 2250

 ggttatttcg gagtgttatt tatcttccca cttgctctct gtttgtattt 2300

 ttgttttgtt tttgattctt gagactgtga ggacttggtt gacttctctg 2350

 cccttaaagt aaatattagt gaaattggtt ccatcagaga taacctcgag 2400

 ttcttggtgt agaaattatg tgaataaagt tgctcaatta gaaaaaaaaa 2450

 aaaaaaaaaa a 2461

<210> 3280
<211> 482
<212> PRT
<213> Homo sapien

<400> 3280
 Met Leu His Ser Met Ser Arg Leu Leu Ser Thr Lys Pro Ser Ser
   1               5                  10                  15

 Ile Ile Ser Thr Lys Thr Phe Ile Met Gln Asn Trp Asn Cys Arg
                  20                  25                  30

 Arg Arg His Arg Tyr Lys Ser Arg Met Asn Lys Thr Tyr Cys Lys
                  35                  40                  45

 Gly Ala Arg Arg Ser Gln Arg Ser Ser Lys Glu Asn Phe Ile Pro
                  50                  55                  60

 Cys Ser Glu Pro Val Lys Gly Thr Gly Ala Leu Arg Asp Cys Lys
                  65                  70                  75

 Asn Val Leu Asp Val Ser Cys Arg Lys Thr Gly Leu Lys Leu Glu
                  80                  85                  90

 Lys Ala Phe Leu Glu Val Asn Arg Pro Gln Ile His Lys Leu Asp
                  95                 100                 105

 Pro Ser Trp Lys Glu Arg Lys Val Thr Pro Ser Lys Tyr Ser Ser
                 110                 115                 120

 Leu Ile Tyr Phe Asp Ser Ser Ala Thr Tyr Asn Leu Asp Glu Glu
                 125                 130                 135

 Asn Arg Phe Arg Thr Leu Lys Trp Leu Ile Ser Pro Val Lys Ile
                 140                 145                 150

 Val Ser Arg Pro Thr Ile Arg Gln Gly His Gly Glu Asn Arg Gln
                 155                 160                 165

 Arg Glu Ile Glu Ile Arg Phe Asp Gln Leu His Arg Glu Tyr Cys
                 170                 175                 180

 Leu Ser Pro Arg Asn Gln Pro Arg Arg Met Cys Leu Pro Asp Ser
                 185                 190                 195

 Trp Ala Met Asn Met Tyr Arg Gly Gly Pro Ala Ser Pro Gly Gly
                 200                 205                 210

 Leu Gln Gly Leu Glu Thr Arg Arg Leu Ser Leu Pro Ser Ser Lys
                 215                 220                 225

 Ala Lys Ala Lys Ser Leu Ser Glu Ala Phe Glu Asn Leu Gly Lys
                 230                 235                 240

 Arg Ser Leu Glu Ala Gly Arg Cys Leu Pro Lys Ser Asp Ser Ser
                 245                 250                 255

 Ser Ser Leu Pro Lys Thr Asn Pro Thr His Ser Ala Thr Arg Pro
                 260                 265                 270

 Gln Gln Thr Ser Asp Leu His Val Gln Gly Asn Ser Ser Gly Ile
                 275                 280                 285

 Phe Arg Lys Ser Val Ser Pro Ser Lys Thr Leu Ser Val Pro Asp
                 290                 295                 300

 Lys Glu Val Pro Gly His Gly Arg Asn Arg Tyr Asp Glu Ile Lys
                 305                 310                 315

 Glu Glu Phe Asp Lys Leu His Gln Lys Tyr Cys Leu Lys Ser Pro
                 320                 325                 330

 Gly Gln Met Thr Val Pro Leu Cys Ile Gly Val Ser Thr Asp Lys
                 335                 340                 345

 Ala Ser Met Glu Val Arg Tyr Gln Thr Glu Gly Phe Leu Gly Lys
                 350                 355                 360

 Leu Asn Pro Asp Pro His Phe Gln Gly Phe Gln Lys Leu Pro Ser
                 365                 370                 375

 Ser Pro Leu Gly Cys Arg Lys Ser Leu Leu Gly Ser Thr Ala Ile
                 380                 385                 390

 Glu Ala Pro Ser Ser Thr Cys Val Ala Arg Ala Ile Thr Arg Asp
                 395                 400                 405

 Gly Thr Arg Asp His Gln Phe Pro Ala Lys Arg Pro Arg Leu Ser
                 410                 415                 420

 Glu Pro Gln Gly Ser Gly Arg Gln Gly Asn Ser Leu Gly Ala Ser
                 425                 430                 435

 Asp Gly Val Asp Asn Thr Val Arg Pro Gly Asp Gln Gly Ser Ser
                 440                 445                 450

 Ser Gln Pro Asn Ser Glu Glu Arg Gly Glu Asn Thr Ser Tyr Arg
                 455                 460                 465

 Met Glu Glu Lys Ser Asp Phe Met Leu Glu Lys Leu Glu Thr Lys
                 470                 475                 480

 Ser Val


<210> 3281
<211> 2972
<212> DNA
<213> Homo sapien

<400> 3281
 tcttcggacc taggctgccc tgccgtcatg tcgcaaggga tcctttctcc 50

 gccagcgggc ttgctgtccg atgacgatgt cgtagtttct cccatgtttg 100

 agtccacagc tgcagatttg gggtctgtgg tacgcaagaa cctgctatca 150

 gactgctctg tcgtctctac ctccctagag gacaagcagc aggttccatc 200

 tgaggacagt atggagaagg tgaaagtata cttgagggtt aggcccttgt 250

 taccttcaga gttggaacga caggaagatc agggttgtgt ccgtattgag 300

 aatgtggaga cccttgttct acaagcaccc aaggactcgt ttgccctgaa 350

 gagcaatgaa cggggaattg gccaagccac acacaggttc accttttccc 400

 agatctttgg gccagaagtg ggacaggcat ccttcttcaa cctaactgtg 450

 aaggagatgg taaaggatgt actcaaaggg cagaactggc tcatctatac 500

 atatggagtc actaactcag ggaaaaccca cacgattcaa ggtaccatca 550

 aggatggagg gattctcccc cggtccctgg cgctgatctt caatagcctc 600

 caaggccaac ttcatccaac acctgatctg aagcccttgc tctccaatga 650

 ggtaatctgg ctagacagca agcagatccg acaggaggaa atgaagaagc 700

 tgtccctgct aaatggaggc ctccaagagg aggagctgtc cacttccttg 750

 aagaggagtg tctacatcga aagtcggata ggtaccagca ccagcttcga 800

 cagtggcatt gctgggctct cttctatcag tcagtgtacc agcagtagcc 850

 agctggatga aacaagtcat cgatgggcac agccagacac tgccccacta 900

 cctgtcccgg caaacattcg cttctccatc tggatctcat tctttgagat 950

 ctacaacgaa ctgctttatg acctattaga accgcctagc caacagcgca 1000

 agaggcagac tttgcggcta tgcgaggatc aaaatggcaa tccctatgtg 1050

 aaagatctca actggattca tgtgcaagat gctgaggagg cctggaagct 1100

 cctaaaagtg ggtcgtaaga accagagctt tgccagcacc cacctcaacc 1150

 agaactccag ccgcagtcac agcatcttct caatcaggat cctacacctt 1200

 cagggggaag gagatatagt ccccaagatc agcgagctgt cactctgtga 1250

 tctggctggc tcagagcgct gcaaagatca gaagagtggt gaacggttga 1300

 aggaagcagg aaacattaac acctctctac acaccctggg ccgctgtatt 1350

 gctgcccttc gtcaaaacca gcagaaccgg tcaaagcaga acctggttcc 1400

 cttccgtgac agcaagttga ctcgagtgtt ccaaggtttc ttcacaggcc 1450

 gaggccgttc ctgcatgatt gtcaatgtga atccctgtgc atctacctat 1500

 gatgaaactc ttcatgtggc caagttctca gccattgcta gccagcttgt 1550

 gcatgcccca cctatgcaac tgggattccc atccctgcac tcgttcatca 1600

 aggaacatag tcttcaggta tcccccagct tagagaaagg ggctaaggca 1650

 gacacaggcc ttgatgatga tattgaaaat gaagctgaca tctccatgta 1700

 tggcaaagag gagctcctac aagttgtgga agccatgaag acactgcttt 1750

 tgaaggaacg acaggaaaag ctacagctgg agatgcatct ccgagatgaa 1800

 atttgcaatg agatggtaga acagatgcaa cagcgggaac agtggtgcag 1850

 tgaacatttg gacacccaaa aggaactatt ggaggaaatg tatgaagaaa 1900

 aactaaatat cctcaaggag tcactgacaa gtttttacca agaagagatt 1950

 caggagcggg atgaaaagat tgaagagcta gaagctctct tgcaggaagc 2000

 cagacaacag tcagtggccc atcagcaatc agggtctgaa ttggccctac 2050

 ggcggtcaca aaggttggca gcttctgcct ccacccagca gcttcaggag 2100

 gttaaagcta aattacagca gtgcaaagca gagctaaact ctaccactga 2150

 agagttgcat aagtatcaga aaatgttaga accaccaccc tcagccaagc 2200

 ccttcaccat tgatgtggac aagaagttag aagagggcca gaagaatata 2250

 aggctgttgc ggacagagct tcagaaactt ggtgagtctc tccaatcagc 2300

 agagagagct tgttgccaca gcactggggc aggaaaactt cgtcaagcct 2350

 tgaccacttg tgatgacatc ttaatcaaac aggaccagac tctggctgaa 2400

 ctgcagaaca acatggtgct agtgaaactg gaccttcgga agaaggcagc 2450

 atgtattgct gagcagtatc atactgtgtt gaaactccaa ggccaggttt 2500

 ctgccaaaaa gcgccttggt accaaccagg aaaatcagca accaaaccaa 2550

 caaccaccag ggaagaaacc attccttcga aatttacttc cccgaacacc 2600

 aacctgccaa agctcaacag actgcagccc ttatgcccgg atcctacgct 2650

 cacggcgttc ccctttactc aaatctgggc cttttggcaa aaagtactaa 2700

 ggctgtgggg aaagagaaga gcagtcatgg ccctgaggtg ggtcagctac 2750

 tctcctgaag aaataggtct cttttatgct ttaccatata tcaggaatta 2800

 tatccaggat gcaatactca gacactagct tttttctcac ttttgtatta 2850

 taaccaccta tgtaatctca tgttgttgtt tttttttatt tacttatatg 2900

 atttctatgc acacaaaaac agttatatta aagatattat tgttcacatt 2950

 ttttattgaa aaaaaaaaaa aa 2972

<210> 3282
<211> 890
<212> PRT
<213> Homo sapien

<400> 3282
 Met Ser Gln Gly Ile Leu Ser Pro Pro Ala Gly Leu Leu Ser Asp
   1               5                  10                  15

 Asp Asp Val Val Val Ser Pro Met Phe Glu Ser Thr Ala Ala Asp
                  20                  25                  30

 Leu Gly Ser Val Val Arg Lys Asn Leu Leu Ser Asp Cys Ser Val
                  35                  40                  45

 Val Ser Thr Ser Leu Glu Asp Lys Gln Gln Val Pro Ser Glu Asp
                  50                  55                  60

 Ser Met Glu Lys Val Lys Val Tyr Leu Arg Val Arg Pro Leu Leu
                  65                  70                  75

 Pro Ser Glu Leu Glu Arg Gln Glu Asp Gln Gly Cys Val Arg Ile
                  80                  85                  90

 Glu Asn Val Glu Thr Leu Val Leu Gln Ala Pro Lys Asp Ser Phe
                  95                 100                 105

 Ala Leu Lys Ser Asn Glu Arg Gly Ile Gly Gln Ala Thr His Arg
                 110                 115                 120

 Phe Thr Phe Ser Gln Ile Phe Gly Pro Glu Val Gly Gln Ala Ser
                 125                 130                 135

 Phe Phe Asn Leu Thr Val Lys Glu Met Val Lys Asp Val Leu Lys
                 140                 145                 150

 Gly Gln Asn Trp Leu Ile Tyr Thr Tyr Gly Val Thr Asn Ser Gly
                 155                 160                 165

 Lys Thr His Thr Ile Gln Gly Thr Ile Lys Asp Gly Gly Ile Leu
                 170                 175                 180

 Pro Arg Ser Leu Ala Leu Ile Phe Asn Ser Leu Gln Gly Gln Leu
                 185                 190                 195

 His Pro Thr Pro Asp Leu Lys Pro Leu Leu Ser Asn Glu Val Ile
                 200                 205                 210

 Trp Leu Asp Ser Lys Gln Ile Arg Gln Glu Glu Met Lys Lys Leu
                 215                 220                 225

 Ser Leu Leu Asn Gly Gly Leu Gln Glu Glu Glu Leu Ser Thr Ser
                 230                 235                 240

 Leu Lys Arg Ser Val Tyr Ile Glu Ser Arg Ile Gly Thr Ser Thr
                 245                 250                 255

 Ser Phe Asp Ser Gly Ile Ala Gly Leu Ser Ser Ile Ser Gln Cys
                 260                 265                 270

 Thr Ser Ser Ser Gln Leu Asp Glu Thr Ser His Arg Trp Ala Gln
                 275                 280                 285

 Pro Asp Thr Ala Pro Leu Pro Val Pro Ala Asn Ile Arg Phe Ser
                 290                 295                 300

 Ile Trp Ile Ser Phe Phe Glu Ile Tyr Asn Glu Leu Leu Tyr Asp
                 305                 310                 315

 Leu Leu Glu Pro Pro Ser Gln Gln Arg Lys Arg Gln Thr Leu Arg
                 320                 325                 330

 Leu Cys Glu Asp Gln Asn Gly Asn Pro Tyr Val Lys Asp Leu Asn
                 335                 340                 345

 Trp Ile His Val Gln Asp Ala Glu Glu Ala Trp Lys Leu Leu Lys
                 350                 355                 360

 Val Gly Arg Lys Asn Gln Ser Phe Ala Ser Thr His Leu Asn Gln
                 365                 370                 375

 Asn Ser Ser Arg Ser His Ser Ile Phe Ser Ile Arg Ile Leu His
                 380                 385                 390

 Leu Gln Gly Glu Gly Asp Ile Val Pro Lys Ile Ser Glu Leu Ser
                 395                 400                 405

 Leu Cys Asp Leu Ala Gly Ser Glu Arg Cys Lys Asp Gln Lys Ser
                 410                 415                 420

 Gly Glu Arg Leu Lys Glu Ala Gly Asn Ile Asn Thr Ser Leu His
                 425                 430                 435

 Thr Leu Gly Arg Cys Ile Ala Ala Leu Arg Gln Asn Gln Gln Asn
                 440                 445                 450

 Arg Ser Lys Gln Asn Leu Val Pro Phe Arg Asp Ser Lys Leu Thr
                 455                 460                 465

 Arg Val Phe Gln Gly Phe Phe Thr Gly Arg Gly Arg Ser Cys Met
                 470                 475                 480

 Ile Val Asn Val Asn Pro Cys Ala Ser Thr Tyr Asp Glu Thr Leu
                 485                 490                 495

 His Val Ala Lys Phe Ser Ala Ile Ala Ser Gln Leu Val His Ala
                 500                 505                 510

 Pro Pro Met Gln Leu Gly Phe Pro Ser Leu His Ser Phe Ile Lys
                 515                 520                 525

 Glu His Ser Leu Gln Val Ser Pro Ser Leu Glu Lys Gly Ala Lys
                 530                 535                 540

 Ala Asp Thr Gly Leu Asp Asp Asp Ile Glu Asn Glu Ala Asp Ile
                 545                 550                 555

 Ser Met Tyr Gly Lys Glu Glu Leu Leu Gln Val Val Glu Ala Met
                 560                 565                 570

 Lys Thr Leu Leu Leu Lys Glu Arg Gln Glu Lys Leu Gln Leu Glu
                 575                 580                 585

 Met His Leu Arg Asp Glu Ile Cys Asn Glu Met Val Glu Gln Met
                 590                 595                 600

 Gln Gln Arg Glu Gln Trp Cys Ser Glu His Leu Asp Thr Gln Lys
                 605                 610                 615

 Glu Leu Leu Glu Glu Met Tyr Glu Glu Lys Leu Asn Ile Leu Lys
                 620                 625                 630

 Glu Ser Leu Thr Ser Phe Tyr Gln Glu Glu Ile Gln Glu Arg Asp
                 635                 640                 645

 Glu Lys Ile Glu Glu Leu Glu Ala Leu Leu Gln Glu Ala Arg Gln
                 650                 655                 660

 Gln Ser Val Ala His Gln Gln Ser Gly Ser Glu Leu Ala Leu Arg
                 665                 670                 675

 Arg Ser Gln Arg Leu Ala Ala Ser Ala Ser Thr Gln Gln Leu Gln
                 680                 685                 690

 Glu Val Lys Ala Lys Leu Gln Gln Cys Lys Ala Glu Leu Asn Ser
                 695                 700                 705

 Thr Thr Glu Glu Leu His Lys Tyr Gln Lys Met Leu Glu Pro Pro
                 710                 715                 720

 Pro Ser Ala Lys Pro Phe Thr Ile Asp Val Asp Lys Lys Leu Glu
                 725                 730                 735

 Glu Gly Gln Lys Asn Ile Arg Leu Leu Arg Thr Glu Leu Gln Lys
                 740                 745                 750

 Leu Gly Glu Ser Leu Gln Ser Ala Glu Arg Ala Cys Cys His Ser
                 755                 760                 765

 Thr Gly Ala Gly Lys Leu Arg Gln Ala Leu Thr Thr Cys Asp Asp
                 770                 775                 780

 Ile Leu Ile Lys Gln Asp Gln Thr Leu Ala Glu Leu Gln Asn Asn
                 785                 790                 795

 Met Val Leu Val Lys Leu Asp Leu Arg Lys Lys Ala Ala Cys Ile
                 800                 805                 810

 Ala Glu Gln Tyr His Thr Val Leu Lys Leu Gln Gly Gln Val Ser
                 815                 820                 825

 Ala Lys Lys Arg Leu Gly Thr Asn Gln Glu Asn Gln Gln Pro Asn
                 830                 835                 840

 Gln Gln Pro Pro Gly Lys Lys Pro Phe Leu Arg Asn Leu Leu Pro
                 845                 850                 855

 Arg Thr Pro Thr Cys Gln Ser Ser Thr Asp Cys Ser Pro Tyr Ala
                 860                 865                 870

 Arg Ile Leu Arg Ser Arg Arg Ser Pro Leu Leu Lys Ser Gly Pro
                 875                 880                 885

 Phe Gly Lys Lys Tyr
                 890

<210> 3283
<211> 4916
<212> DNA
<213> Homo sapien

<400> 3283
 agaattcgga gcgcggaaga gccagagctg cgagcgcctg gagctggatc 50

 tctctccggt cgcgcacgcc gaggccagta gggagagaag atggtggttc 100

 tccgcagcag cttggagctg cacaaccact ccgcggcctc ggccacgggc 150

 tccttggacc tgtccagtga cttcctcagt ctggagcaca tcggccggag 200

 gcggctccgc tcggccggcg cggcgcagaa gaaacccgcg gcgaccacag 250

 ccaaagcggg cgatgggtca tcagttaagg aagttgaaac ctaccaccgg 300

 acacgtgctt taagatcttt gagaaaagat gcacagaatt cttcagattc 350

 tagttttgag aagaatgtgg aaataacgga gcaacttgct aatggcaggc 400

 attttacaag gcagttggcc agacagcagg ctgataaaaa aaaagaagag 450

 cacagagaag acaaagtgat tccagttact cggtcattga gggctagaaa 500

 catcgttcaa agtacagaac acttacatga agataatggt gatgttgaag 550

 tgcgtcgaag ttgtaggatt agaagtcgtt atagtggtgt aaaccagtcc 600

 atgctgtttg acaaacttat aactaacact gctgaagctg tacttcaaaa 650

 aatggatgac atgaagaaga tgcgtagaca gcgaatgaga gaacttgaag 700

 acttgggagt gtttaatgaa acagaagaaa gcaatcttaa tatgtacaca 750

 agaggaaaac agaaagatat tcaaagaact gatgaagaaa caactgataa 800

 tcaagaaggc agtgtggagt catctgaaga gggtgaagac caagaacatg 850

 aagatgatgg tgaagatgaa gatgatgaag atgatgatga tgatgacgat 900

 gatgatgatg atgatgatga tgaagatgat gaagatgaag aagatggaga 950

 agaagagaat cagaagcgat attatcttag acagagaaaa gctactgttt 1000

 actatcaggc tccattggaa aaacctcgtc accagagaaa gcccaacata 1050

 ttttatagtg gcccagcttc tcctgcaaga ccaagatacc gattatcttc 1100

 cgcaggacca agaagtcctt actgtaaacg aatgaacagg cgaaggcatg 1150

 caatccacag tagtgactcg acttcatctt cctcctctga agatgaacag 1200

 cactttgaga ggcggaggaa aaggagtcgt aatagggcta tcaataggtg 1250

 cctcccacta aattttcgga aagatgaatt aaaaggcatt tataaagatc 1300

 gaatgaaaat tggagcaagc cttgccgatg ttgatccaat gcaactagat 1350

 tcttcagtac gatttgatag tgttggtggc ctgtctaatc atatagcagc 1400

 tctaaaagag atggtggtgt ttccattact ttatccagaa gtctttgaaa 1450

 aatttaaaat tcaaccccca agaggttgtt tgttttatgg gccacctgga 1500

 actggaaaga ctctggttgc cagagcactt gccaatgagt gcagtcaagg 1550

 ggataaaaga gtagcatttt tcatgaggaa aggtgctgat tgtctaagta 1600

 aatgggtagg agaatctgaa agacagctac gattgctgtt tgatcaggcc 1650

 tatcagatgc gcccatcaat tatttttttt gacgaaattg atggtctggc 1700

 tccagtacgg tcaagcaggc aagatcagat tcacagttct attgtttcca 1750

 ccctgctagc tcttatggat ggattggaca gcagagggga aattgtggtc 1800

 attggtgcta cgaacaggct agattctata gatcctgctt tacgaaggcc 1850

 tggtcgcttt gatagagaat tcctctttag cctgcctgat aaagaggctc 1900

 gaaaagagat tctaaagatt cacaccaggg attggaatcc caaaccactg 1950

 gacacatttt tagaagagct agcagaaaac tgtgttggat actgtggagc 2000

 agatattaaa tcaatatgtg ctgaagctgc tttatgtgct ttacgacgac 2050

 gctacccaca gatctatacc actagtgaga aactgcagtt ggatctctct 2100

 tcaattaata tctcagctaa ggatttcgag gtagctatgc aaaagatgat 2150

 accagcctcc caaagagctg tgacatcacc tgggcaggca ctgtccaccg 2200

 ttgtgaaacc actcctgcaa aacactgttg acaagatttt agaagccctg 2250

 cagagagtat ttccacatgc agaattcaga acaaataaaa cattagactc 2300

 agatatttct tgtcctctgc tagaaagtga cttggcttac agtgatgatg 2350

 atgttccatc agtttatgaa aatggacttt ctcagaaatc ttctcataag 2400

 gcaaaagaca attttaattt tcttcatttg aatagaaatg cttgttacca 2450

 acctatgtct tttcgaccaa gaatattgat agtaggagaa ccaggatttg 2500

 ggcaaggttc tcacttggca ccagctgtca ttcatgcttt ggaaaagttt 2550

 actgtatata cattagacat tcctgttctt tttggagtta gtactacatc 2600

 ccctgaagaa acatgtgccc aggtgattcg tgaagctaag agaacagcac 2650

 caagtatagt gtatgttcct catatccacg tgtggtggga aatagttgga 2700

 ccgacactta aagccacatt taccacatta ttacagaata ttccttcatt 2750

 tgctccagtt ttactacttg caacttctga caaaccccat tccgctttgc 2800

 cagaagaggt gcaagaattg tttatccgtg attatggaga gatttttaat 2850

 gtccagttac cggataaaga agaacggaca aaattttttg aagatttaat 2900

 tctaaaacaa gctgctaagc ctcctatatc aaaaaagaaa gcagttttgc 2950

 aggctttgga ggtactccca gtagcaccac cacctgagcc aagatcactg 3000

 acagcagaag aagtgaaacg actagaagaa caagaagaag atacatttag 3050

 agaactgagg attttcttaa gaaatgttac acataggctt gctattgaca 3100

 agcgattccg agtgtttact aagcctgttg accctgatga ggttcctgat 3150

 tatgtcactg taataaagca accaatggac ctttcatctg taatcagtaa 3200

 aattgatcta cacaagtatc tgactgtgaa agactatttg agagatattg 3250

 atctaatctg tagtaatgcc ttagaataca atccagatag agatcctgga 3300

 gatcgtctta ttaggcatag agcctgtgct ttaagagata ctgcctatgc 3350

 cataattaaa gaagaacttg atgaagactt tgagcagctc tgtgaagaaa 3400

 ttcaggaatc tagaaagaaa agaggttgta gctcctccaa atatgccccg 3450

 tcttactacc atgtgatgcc aaagcaaaat tccactcttg ttggtgataa 3500

 aagatcagac ccagagcaga atgaaaagct aaagacaccg agtactcctg 3550

 tggcttgcag cactcctgct cagttgaaga ggaaaattcg caaaaagtca 3600

 aactggtact taggcaccat aaaaaagcga aggaagattt cacaggcaaa 3650

 ggatgatagc cagaatgcca tagatcacaa aattgagagt gatacagagg 3700

 aaactcaaga cacaagtgta gatcataatg agaccggaaa cacaggagag 3750

 tcttcggtgg aagaaaatga aaaacagcaa aatgcctctg aaagcaaact 3800

 ggaattgaga aataattcaa atacttgtaa tatagagaat gagcttgaag 3850

 actctaggaa gactacagca tgtacagaat tgagagacaa gattgcttgt 3900

 aatggagatg cttctagctc tcagataata catatttctg atgaaaatga 3950

 aggaaaagaa atgtgtgttc tgcgaatgac tcgagctaga cgttcccagg 4000

 tagaacagca gcagctcatc actgttgaaa aggctttggc aattctttct 4050

 cagcctacac cctcacttgt tgtggatcat gagcgattaa aaaatctttt 4100

 gaagactgtt gttaaaaaaa gtcaaaacta caacatattt cagttggaaa 4150

 atttgtatgc agtaatcagc caatgtattt atcggcatcg caaggaccat 4200

 gataaaacat cacttattca gaaaatggag caagaggtag aaaacttcag 4250

 ttgttccaga tgatgatgtc atggtatcga gtattcttta tattcagttc 4300

 ctatttaagt catttttgtc atgtccgcct aattgatgta gtatgaaacc 4350

 ctgcatcttt aaggaaaaga ttaaaatagt aaaataaaag tatttaaact 4400

 ttcctgatat ttatgtacat attaagataa atgtcatgtg taagataact 4450

 gataaatatt ggaactttgc tagaacaaga ccctgtagta atagtaataa 4500

 tagttgaagt ttggccaact cttaataaag ttattttggt aactaatgtt 4550

 ttatggcact taagaataat tagcagcgtt aaattttgtt tgtattaagc 4600

 acttttaatt ttatccttcc taaaaatagt ttattgtatc tgacaagaaa 4650

 cttacttaac cattgtgtcc ttcccatctt ttttgtcatc tttgttttct 4700

 tcaaatgccc tcctcccatc tgccttgaga ttcccttgtc ttcacttaaa 4750

 agccagagtg caagtcatga tttgcgggag ggctcttgaa ccacttctgg 4800

 ctgcaccaca attctgtact tgagtatcac agtcattgtt tttgagacaa 4850

 acatttttat aattctaatt tgggttaata aagattttaa atatttaaaa 4900

 aaaaaaaaaa aaaaaa 4916

<210> 3284
<211> 1390
<212> PRT
<213> Homo sapien

<400> 3284
 Met Val Val Leu Arg Ser Ser Leu Glu Leu His Asn His Ser Ala
   1               5                  10                  15

 Ala Ser Ala Thr Gly Ser Leu Asp Leu Ser Ser Asp Phe Leu Ser
                  20                  25                  30

 Leu Glu His Ile Gly Arg Arg Arg Leu Arg Ser Ala Gly Ala Ala
                  35                  40                  45

 Gln Lys Lys Pro Ala Ala Thr Thr Ala Lys Ala Gly Asp Gly Ser
                  50                  55                  60

 Ser Val Lys Glu Val Glu Thr Tyr His Arg Thr Arg Ala Leu Arg
                  65                  70                  75

 Ser Leu Arg Lys Asp Ala Gln Asn Ser Ser Asp Ser Ser Phe Glu
                  80                  85                  90

 Lys Asn Val Glu Ile Thr Glu Gln Leu Ala Asn Gly Arg His Phe
                  95                 100                 105

 Thr Arg Gln Leu Ala Arg Gln Gln Ala Asp Lys Lys Lys Glu Glu
                 110                 115                 120

 His Arg Glu Asp Lys Val Ile Pro Val Thr Arg Ser Leu Arg Ala
                 125                 130                 135

 Arg Asn Ile Val Gln Ser Thr Glu His Leu His Glu Asp Asn Gly
                 140                 145                 150

 Asp Val Glu Val Arg Arg Ser Cys Arg Ile Arg Ser Arg Tyr Ser
                 155                 160                 165

 Gly Val Asn Gln Ser Met Leu Phe Asp Lys Leu Ile Thr Asn Thr
                 170                 175                 180

 Ala Glu Ala Val Leu Gln Lys Met Asp Asp Met Lys Lys Met Arg
                 185                 190                 195

 Arg Gln Arg Met Arg Glu Leu Glu Asp Leu Gly Val Phe Asn Glu
                 200                 205                 210

 Thr Glu Glu Ser Asn Leu Asn Met Tyr Thr Arg Gly Lys Gln Lys
                 215                 220                 225

 Asp Ile Gln Arg Thr Asp Glu Glu Thr Thr Asp Asn Gln Glu Gly
                 230                 235                 240

 Ser Val Glu Ser Ser Glu Glu Gly Glu Asp Gln Glu His Glu Asp
                 245                 250                 255

 Asp Gly Glu Asp Glu Asp Asp Glu Asp Asp Asp Asp Asp Asp Asp
                 260                 265                 270

 Asp Asp Asp Asp Asp Asp Asp Glu Asp Asp Glu Asp Glu Glu Asp
                 275                 280                 285

 Gly Glu Glu Glu Asn Gln Lys Arg Tyr Tyr Leu Arg Gln Arg Lys
                 290                 295                 300

 Ala Thr Val Tyr Tyr Gln Ala Pro Leu Glu Lys Pro Arg His Gln
                 305                 310                 315

 Arg Lys Pro Asn Ile Phe Tyr Ser Gly Pro Ala Ser Pro Ala Arg
                 320                 325                 330

 Pro Arg Tyr Arg Leu Ser Ser Ala Gly Pro Arg Ser Pro Tyr Cys
                 335                 340                 345

 Lys Arg Met Asn Arg Arg Arg His Ala Ile His Ser Ser Asp Ser
                 350                 355                 360

 Thr Ser Ser Ser Ser Ser Glu Asp Glu Gln His Phe Glu Arg Arg
                 365                 370                 375

 Arg Lys Arg Ser Arg Asn Arg Ala Ile Asn Arg Cys Leu Pro Leu
                 380                 385                 390

 Asn Phe Arg Lys Asp Glu Leu Lys Gly Ile Tyr Lys Asp Arg Met
                 395                 400                 405

 Lys Ile Gly Ala Ser Leu Ala Asp Val Asp Pro Met Gln Leu Asp
                 410                 415                 420

 Ser Ser Val Arg Phe Asp Ser Val Gly Gly Leu Ser Asn His Ile
                 425                 430                 435

 Ala Ala Leu Lys Glu Met Val Val Phe Pro Leu Leu Tyr Pro Glu
                 440                 445                 450

 Val Phe Glu Lys Phe Lys Ile Gln Pro Pro Arg Gly Cys Leu Phe
                 455                 460                 465

 Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu Val Ala Arg Ala Leu
                 470                 475                 480

 Ala Asn Glu Cys Ser Gln Gly Asp Lys Arg Val Ala Phe Phe Met
                 485                 490                 495

 Arg Lys Gly Ala Asp Cys Leu Ser Lys Trp Val Gly Glu Ser Glu
                 500                 505                 510

 Arg Gln Leu Arg Leu Leu Phe Asp Gln Ala Tyr Gln Met Arg Pro
                 515                 520                 525

 Ser Ile Ile Phe Phe Asp Glu Ile Asp Gly Leu Ala Pro Val Arg
                 530                 535                 540

 Ser Ser Arg Gln Asp Gln Ile His Ser Ser Ile Val Ser Thr Leu
                 545                 550                 555

 Leu Ala Leu Met Asp Gly Leu Asp Ser Arg Gly Glu Ile Val Val
                 560                 565                 570

 Ile Gly Ala Thr Asn Arg Leu Asp Ser Ile Asp Pro Ala Leu Arg
                 575                 580                 585

 Arg Pro Gly Arg Phe Asp Arg Glu Phe Leu Phe Ser Leu Pro Asp
                 590                 595                 600

 Lys Glu Ala Arg Lys Glu Ile Leu Lys Ile His Thr Arg Asp Trp
                 605                 610                 615

 Asn Pro Lys Pro Leu Asp Thr Phe Leu Glu Glu Leu Ala Glu Asn
                 620                 625                 630

 Cys Val Gly Tyr Cys Gly Ala Asp Ile Lys Ser Ile Cys Ala Glu
                 635                 640                 645

 Ala Ala Leu Cys Ala Leu Arg Arg Arg Tyr Pro Gln Ile Tyr Thr
                 650                 655                 660

 Thr Ser Glu Lys Leu Gln Leu Asp Leu Ser Ser Ile Asn Ile Ser
                 665                 670                 675

 Ala Lys Asp Phe Glu Val Ala Met Gln Lys Met Ile Pro Ala Ser
                 680                 685                 690

 Gln Arg Ala Val Thr Ser Pro Gly Gln Ala Leu Ser Thr Val Val
                 695                 700                 705

 Lys Pro Leu Leu Gln Asn Thr Val Asp Lys Ile Leu Glu Ala Leu
                 710                 715                 720

 Gln Arg Val Phe Pro His Ala Glu Phe Arg Thr Asn Lys Thr Leu
                 725                 730                 735

 Asp Ser Asp Ile Ser Cys Pro Leu Leu Glu Ser Asp Leu Ala Tyr
                 740                 745                 750

 Ser Asp Asp Asp Val Pro Ser Val Tyr Glu Asn Gly Leu Ser Gln
                 755                 760                 765

 Lys Ser Ser His Lys Ala Lys Asp Asn Phe Asn Phe Leu His Leu
                 770                 775                 780

 Asn Arg Asn Ala Cys Tyr Gln Pro Met Ser Phe Arg Pro Arg Ile
                 785                 790                 795

 Leu Ile Val Gly Glu Pro Gly Phe Gly Gln Gly Ser His Leu Ala
                 800                 805                 810

 Pro Ala Val Ile His Ala Leu Glu Lys Phe Thr Val Tyr Thr Leu
                 815                 820                 825

 Asp Ile Pro Val Leu Phe Gly Val Ser Thr Thr Ser Pro Glu Glu
                 830                 835                 840

 Thr Cys Ala Gln Val Ile Arg Glu Ala Lys Arg Thr Ala Pro Ser
                 845                 850                 855

 Ile Val Tyr Val Pro His Ile His Val Trp Trp Glu Ile Val Gly
                 860                 865                 870

 Pro Thr Leu Lys Ala Thr Phe Thr Thr Leu Leu Gln Asn Ile Pro
                 875                 880                 885

 Ser Phe Ala Pro Val Leu Leu Leu Ala Thr Ser Asp Lys Pro His
                 890                 895                 900

 Ser Ala Leu Pro Glu Glu Val Gln Glu Leu Phe Ile Arg Asp Tyr
                 905                 910                 915

 Gly Glu Ile Phe Asn Val Gln Leu Pro Asp Lys Glu Glu Arg Thr
                 920                 925                 930

 Lys Phe Phe Glu Asp Leu Ile Leu Lys Gln Ala Ala Lys Pro Pro
                 935                 940                 945

 Ile Ser Lys Lys Lys Ala Val Leu Gln Ala Leu Glu Val Leu Pro
                 950                 955                 960

 Val Ala Pro Pro Pro Glu Pro Arg Ser Leu Thr Ala Glu Glu Val
                 965                 970                 975

 Lys Arg Leu Glu Glu Gln Glu Glu Asp Thr Phe Arg Glu Leu Arg
                 980                 985                 990

 Ile Phe Leu Arg Asn Val Thr His Arg Leu Ala Ile Asp Lys Arg
                 995                1000                1005

 Phe Arg Val Phe Thr Lys Pro Val Asp Pro Asp Glu Val Pro Asp
                1010                1015                1020

 Tyr Val Thr Val Ile Lys Gln Pro Met Asp Leu Ser Ser Val Ile
                1025                1030                1035

 Ser Lys Ile Asp Leu His Lys Tyr Leu Thr Val Lys Asp Tyr Leu
                1040                1045                1050

 Arg Asp Ile Asp Leu Ile Cys Ser Asn Ala Leu Glu Tyr Asn Pro
                1055                1060                1065

 Asp Arg Asp Pro Gly Asp Arg Leu Ile Arg His Arg Ala Cys Ala
                1070                1075                1080

 Leu Arg Asp Thr Ala Tyr Ala Ile Ile Lys Glu Glu Leu Asp Glu
                1085                1090                1095

 Asp Phe Glu Gln Leu Cys Glu Glu Ile Gln Glu Ser Arg Lys Lys
                1100                1105                1110

 Arg Gly Cys Ser Ser Ser Lys Tyr Ala Pro Ser Tyr Tyr His Val
                1115                1120                1125

 Met Pro Lys Gln Asn Ser Thr Leu Val Gly Asp Lys Arg Ser Asp
                1130                1135                1140

 Pro Glu Gln Asn Glu Lys Leu Lys Thr Pro Ser Thr Pro Val Ala
                1145                1150                1155

 Cys Ser Thr Pro Ala Gln Leu Lys Arg Lys Ile Arg Lys Lys Ser
                1160                1165                1170

 Asn Trp Tyr Leu Gly Thr Ile Lys Lys Arg Arg Lys Ile Ser Gln
                1175                1180                1185

 Ala Lys Asp Asp Ser Gln Asn Ala Ile Asp His Lys Ile Glu Ser
                1190                1195                1200

 Asp Thr Glu Glu Thr Gln Asp Thr Ser Val Asp His Asn Glu Thr
                1205                1210                1215

 Gly Asn Thr Gly Glu Ser Ser Val Glu Glu Asn Glu Lys Gln Gln
                1220                1225                1230

 Asn Ala Ser Glu Ser Lys Leu Glu Leu Arg Asn Asn Ser Asn Thr
                1235                1240                1245

 Cys Asn Ile Glu Asn Glu Leu Glu Asp Ser Arg Lys Thr Thr Ala
                1250                1255                1260

 Cys Thr Glu Leu Arg Asp Lys Ile Ala Cys Asn Gly Asp Ala Ser
                1265                1270                1275

 Ser Ser Gln Ile Ile His Ile Ser Asp Glu Asn Glu Gly Lys Glu
                1280                1285                1290

 Met Cys Val Leu Arg Met Thr Arg Ala Arg Arg Ser Gln Val Glu
                1295                1300                1305

 Gln Gln Gln Leu Ile Thr Val Glu Lys Ala Leu Ala Ile Leu Ser
                1310                1315                1320

 Gln Pro Thr Pro Ser Leu Val Val Asp His Glu Arg Leu Lys Asn
                1325                1330                1335

 Leu Leu Lys Thr Val Val Lys Lys Ser Gln Asn Tyr Asn Ile Phe
                1340                1345                1350

 Gln Leu Glu Asn Leu Tyr Ala Val Ile Ser Gln Cys Ile Tyr Arg
                1355                1360                1365

 His Arg Lys Asp His Asp Lys Thr Ser Leu Ile Gln Lys Met Glu
                1370                1375                1380

 Gln Glu Val Glu Asn Phe Ser Cys Ser Arg
                1385                1390

<210> 3285
<211> 2085
<212> DNA
<213> Homo sapien

<400> 3285
 ggctgcagtt acagagtgct gccatcacca agtatgtggc ggacgtcctg 50

 ccggggaaga atcaaagagc agagagcatg gccagtgcag cgagggaact 100

 ggttatccag cggttgagtc tggtgaggag tctttgcgag agcgaggagc 150

 agcggttact ggaacaggtg catggcgaag aggagcgggc ccaccagagc 200

 atcctgacac agcgggtgca ctgggccgag gcgctgcaga aacttgacac 250

 catccgcact ggcctggtgg gcatgcttac tcacctggat gacctccagc 300

 tgattcagaa ggagcaagag attttcgaga ggaccgaaga agcagagggc 350

 attttggatc cccaggagtc ggaaatgtta aactttaatg agaagtgcac 400

 tcggagccca ctactgaccc aactctgggc aacggcggtt cttgggtctc 450

 tctcaggcac agaggacata cggatcgatg agaggacagt cagccccttc 500

 ctgcaattgt cagatgatcg aaagaccctg accttcagca ccaagaagtc 550

 aaaggcctgt gcagatggcc cggagcgctt cgaccactgg cccaatgccc 600

 tggctgccac ctccttccag aatgggctcc atgcctggat ggtgaatgtc 650

 cagaacagtt gtgcctataa ggtgggcgtg gcttcaggcc acctgccccg 700

 caagggttct ggcagtgact gccgtctggg ccacaatgcc ttctcctggg 750

 tcttctctcg ctatgatcag gagtttcgtt tctcacacaa tgggcagcac 800

 gagcccctgg ggctgctgcg gggcccagcc cagctgggtg tagtgctgga 850

 cttgcaggtt caggagctgc tcttctatga gccagcctcc ggcatagtgc 900

 tctgtgccca tcatgtgtcc ttcccggggc ccctcttccc agtctttgct 950

 gtggccgatc agaccatttc tatcgtccgc tgacctctgg ccacaggaag 1000

 ccaggtccac cgcccaccac cctttcaggc catgtttcta ctcagtgtgc 1050

 ttttcccaaa tgatgtgtgt ggtgtttcta agagaaacag ggcccataac 1100

 cagtgggcag ctttaggagg gatggggatc tgtttcagat ctaggcataa 1150

 cctgtaaatc acaggtgtcc aaacttttgg cttccctggg ccacatttga 1200

 agaagaattt tcttgggcca cataaaatac actaacgata gctgatgagc 1250

 taaaaaaaaa aaaaaaagtc tgtgtataat ttttgtgata tctgccacca 1300

 cagataagca aaaaagtcct tgcattcaaa gggttggaga ttgctgcttt 1350

 gagtgctggg tacctgtggg gaacctacta ctccctgggc cttagtctcc 1400

 caaatccacc atgcatctgc ccctctgagg gtgtcttcac tttgtctctg 1450

 gcatctagca tggtgcctgg tgcatagtga gcatgcaata aatatttggc 1500

 aggtgagtgg atggatagat ggataggtga atgtaggtgg acaggtgact 1550

 gggtggatgt tgtggtctct ggagaagcac tgccattcag cctcctgctc 1600

 cagctgttca catgcagaaa tgctctcttc acaggcagag aagcctgtgg 1650

 ctaaagtttc cacatcccat taactcagtg cttttgtctt tttcatgaca 1700

 tggcacatag agaaaatatt tttttctagc acacaagagc aacctgaaag 1750

 gctgctcctg gctaggggac tctgtcccgg gggaccgtgt cctcccccat 1800

 gtcctgccta ggccctcaga ggaccagggg atcatgtctc caggtaaccc 1850

 gactgtagcc cctgctggct gagctccagc ctgtgcccac tgataatagc 1900

 agggacggcc tttctcttag agcagctgat aagtttccct acctgatggc 1950

 cccctctgac ataaactgca cacctggggt gatggcttaa agccagaaag 2000

 agctgaggga gttaagaggg ccaaccttag ggcacgtggg cattattaaa 2050

 ggtcttaaaa gcattaaaaa aaaaaaaaaa aaaaa 2085

<210> 3286
<211> 301
<212> PRT
<213> Homo sapien

<400> 3286
 Met Ala Ser Ala Ala Arg Glu Leu Val Ile Gln Arg Leu Ser Leu
   1               5                  10                  15

 Val Arg Ser Leu Cys Glu Ser Glu Glu Gln Arg Leu Leu Glu Gln
                  20                  25                  30

 Val His Gly Glu Glu Glu Arg Ala His Gln Ser Ile Leu Thr Gln
                  35                  40                  45

 Arg Val His Trp Ala Glu Ala Leu Gln Lys Leu Asp Thr Ile Arg
                  50                  55                  60

 Thr Gly Leu Val Gly Met Leu Thr His Leu Asp Asp Leu Gln Leu
                  65                  70                  75

 Ile Gln Lys Glu Gln Glu Ile Phe Glu Arg Thr Glu Glu Ala Glu
                  80                  85                  90

 Gly Ile Leu Asp Pro Gln Glu Ser Glu Met Leu Asn Phe Asn Glu
                  95                 100                 105

 Lys Cys Thr Arg Ser Pro Leu Leu Thr Gln Leu Trp Ala Thr Ala
                 110                 115                 120

 Val Leu Gly Ser Leu Ser Gly Thr Glu Asp Ile Arg Ile Asp Glu
                 125                 130                 135

 Arg Thr Val Ser Pro Phe Leu Gln Leu Ser Asp Asp Arg Lys Thr
                 140                 145                 150

 Leu Thr Phe Ser Thr Lys Lys Ser Lys Ala Cys Ala Asp Gly Pro
                 155                 160                 165

 Glu Arg Phe Asp His Trp Pro Asn Ala Leu Ala Ala Thr Ser Phe
                 170                 175                 180

 Gln Asn Gly Leu His Ala Trp Met Val Asn Val Gln Asn Ser Cys
                 185                 190                 195

 Ala Tyr Lys Val Gly Val Ala Ser Gly His Leu Pro Arg Lys Gly
                 200                 205                 210

 Ser Gly Ser Asp Cys Arg Leu Gly His Asn Ala Phe Ser Trp Val
                 215                 220                 225

 Phe Ser Arg Tyr Asp Gln Glu Phe Arg Phe Ser His Asn Gly Gln
                 230                 235                 240

 His Glu Pro Leu Gly Leu Leu Arg Gly Pro Ala Gln Leu Gly Val
                 245                 250                 255

 Val Leu Asp Leu Gln Val Gln Glu Leu Leu Phe Tyr Glu Pro Ala
                 260                 265                 270

 Ser Gly Ile Val Leu Cys Ala His His Val Ser Phe Pro Gly Pro
                 275                 280                 285

 Leu Phe Pro Val Phe Ala Val Ala Asp Gln Thr Ile Ser Ile Val
                 290                 295                 300

 Arg


<210> 3287
<211> 1812
<212> DNA
<213> Homo sapien

<400> 3287
 gttcccaatc agtttccagc caacaccagg gtgtcctagt ccgcagaggt 50

 gtgggggaca cactccataa tctctacttt tctttttgtg cagctgagtc 100

 atggagcttt cagccccagc acatggctcc tccttaactg cgtctgctca 150

 acctccctca gccctgtgaa cagcatcccc gcacacagac gcagagcagg 200

 actctctctg ctgccacttc accttcctga gagaggacca gcggccagag 250

 cctcagtgac tgccaccctg gaggacaggg cacaacaacc gtttctggag 300

 agaatgggag gattccagag gggcaaatat ggaactatgg ctgaaggtag 350

 atcagaagat aacttgtctg caacaccacc ggcattgagg attatcctag 400

 tgggcaaaac aggctgcggg aaaagtgcca cagggaacag catccttggc 450

 cagcccgtgt ttgagtccaa gctgagggcc cagtcagtga ccaggacgtg 500

 ccaggtgaaa acaggaacat ggaacgggag gaaagtcctg gtggttgaca 550

 cgccctccat ctttgagtca caggccgata cccaagagct gtacaagaac 600

 atcggggact gctacctgct ctctgccccg gggccccacg tcctgcttct 650

 ggtgatccag ctggggcgtt tcactgctca ggacacagtg gccatcagga 700

 aggtgaaaga ggtctttggg acaggggcca tgagacatgt ggtcatcctc 750

 ttcacccaca aagaggactt agggggccag gccctggatg actatgtagc 800

 aaacacggac aactgcagcc tgaaagacct ggtgcgggag tgtgagagaa 850

 ggtactgtgc cttcaacaac tggggctctg tggaggagca gaggcagcag 900

 caggcagagc tcctggctgt gattgagagg ctggggaggg agcgagaggg 950

 ctccttccac agcaatgacc tcttcttgga tgcccagctg ctccaaagaa 1000

 ctggagctgg ggcctgccag gaagactaca ggcagtacca ggccaaagtg 1050

 gaatggcagg tggagaagca caagcaagag ctgagggaga acgagagtaa 1100

 ctgggcatac aaggcgctcc tcagagtcaa acacttgatg cttttgcatt 1150

 atgagatttt tgtttttcta ttgttgtgca gcatactttt tttcattatt 1200

 tttctgttca tctttcatta catttaaatc tctggaccct ggagcacttc 1250

 taatgtatca ccccatggag tcattgttct aataatcacc aattcagact 1300

 cagatcctcg tggtctatgg agcatgctgc ttgctgtctg tgcagctccc 1350

 atttcccctt cttcctgata gacttggagc tgtgtgcctc cactccaagg 1400

 ctgcctgcct gctgtaaaca ctattccact ctgtctgcca acaactgctt 1450

 caggaatggg cctgagatcc catgcaggtc cctgagaagt gagtaaaagt 1500

 ccgcagaggt ggggatggaa gatctctcct tagatagaac ctgtcttcct 1550

 ccctggcatt gtggggtctg ggcgtgacac tgggactctc agcagctttg 1600

 tgctgccaac ctgagattga aggcagtgcc tcagagcagc acagagagtt 1650

 ggggccccct gagccctgag ccaccagccc tgcagcctgc cctatctccg 1700

 catttccagt tgtattagcc aatagatttc ctacttattt aagctatttg 1750

 agctccgggt ctcttctacc tgcattctaa aacattcaaa gtaataaaaa 1800

 tttctccaca tt 1812

<210> 3288
<211> 307
<212> PRT
<213> Homo sapien

<400> 3288
 Met Gly Gly Phe Gln Arg Gly Lys Tyr Gly Thr Met Ala Glu Gly
   1               5                  10                  15

 Arg Ser Glu Asp Asn Leu Ser Ala Thr Pro Pro Ala Leu Arg Ile
                  20                  25                  30

 Ile Leu Val Gly Lys Thr Gly Cys Gly Lys Ser Ala Thr Gly Asn
                  35                  40                  45

 Ser Ile Leu Gly Gln Pro Val Phe Glu Ser Lys Leu Arg Ala Gln
                  50                  55                  60

 Ser Val Thr Arg Thr Cys Gln Val Lys Thr Gly Thr Trp Asn Gly
                  65                  70                  75

 Arg Lys Val Leu Val Val Asp Thr Pro Ser Ile Phe Glu Ser Gln
                  80                  85                  90

 Ala Asp Thr Gln Glu Leu Tyr Lys Asn Ile Gly Asp Cys Tyr Leu
                  95                 100                 105

 Leu Ser Ala Pro Gly Pro His Val Leu Leu Leu Val Ile Gln Leu
                 110                 115                 120

 Gly Arg Phe Thr Ala Gln Asp Thr Val Ala Ile Arg Lys Val Lys
                 125                 130                 135

 Glu Val Phe Gly Thr Gly Ala Met Arg His Val Val Ile Leu Phe
                 140                 145                 150

 Thr His Lys Glu Asp Leu Gly Gly Gln Ala Leu Asp Asp Tyr Val
                 155                 160                 165

 Ala Asn Thr Asp Asn Cys Ser Leu Lys Asp Leu Val Arg Glu Cys
                 170                 175                 180

 Glu Arg Arg Tyr Cys Ala Phe Asn Asn Trp Gly Ser Val Glu Glu
                 185                 190                 195

 Gln Arg Gln Gln Gln Ala Glu Leu Leu Ala Val Ile Glu Arg Leu
                 200                 205                 210

 Gly Arg Glu Arg Glu Gly Ser Phe His Ser Asn Asp Leu Phe Leu
                 215                 220                 225

 Asp Ala Gln Leu Leu Gln Arg Thr Gly Ala Gly Ala Cys Gln Glu
                 230                 235                 240

 Asp Tyr Arg Gln Tyr Gln Ala Lys Val Glu Trp Gln Val Glu Lys
                 245                 250                 255

 His Lys Gln Glu Leu Arg Glu Asn Glu Ser Asn Trp Ala Tyr Lys
                 260                 265                 270

 Ala Leu Leu Arg Val Lys His Leu Met Leu Leu His Tyr Glu Ile
                 275                 280                 285

 Phe Val Phe Leu Leu Leu Cys Ser Ile Leu Phe Phe Ile Ile Phe
                 290                 295                 300

 Leu Phe Ile Phe His Tyr Ile
                 305

<210> 3289
<211> 2764
<212> DNA
<213> Homo sapien

<400> 3289
 agacgcgcaa gggcgccgat ggaggcagac tcgccagcgg gccccggcgc 50

 cccagagccc ctcgcggagg gagcggcggc cgagttctcc agcctgctgc 100

 gcaggataaa aggcaaactc ttcacctgga atattttgaa aacaattgcc 150

 ctgggtcaga cgttgtcctt gtgtatatgt gggacagcca tcaccagcca 200

 gtatttggca gaaagataca aagtgaacac ccccatgctt cagagcttta 250

 tcaattattg cttgctgttc ctaatttata cagtgatgct ggcatttcga 300

 tcaggcagtg ataacctttt agtaatcttg aaaagaaaat ggtggaagta 350

 catcctgctg ggactagcag atgtggaagc taattatgtg atcgtcagag 400

 cctaccagta cacaactcta accagtgtcc agcttttgga ttgctttggg 450

 attcctgtgt tgatggctct gtcatggttt attcttcatg caagatacag 500

 agtgatccac ttcatcgccg tggctgtctg tctgttgggt gtaggaacca 550

 tggttggtgc agacatacta gcagggaggg aagacaattc agggagtgat 600

 gtattgattg gtgacatctt ggtccttctt ggggcttccc tctatgccat 650

 ttcaaatgtt tgtgaggaat acatcgtgaa gaagctgagc agacaggagt 700

 ttttaggaat ggtgggcctg tttggaacaa ttatcagtgg tatacagcta 750

 ttgattgtgg aatataagga tattgccagc attcattggg actggaaaat 800

 tgccctgctg ttcgtggcat ttgccctgtg tatgttttgc ctgtacagct 850

 tcatgccatt ggtgattaaa gtcactagtg ccacttccgt caacctgggc 900

 atcctgacag cggacctcta cagccttttt gttggactct ttctgtttgg 950

 ctataagttt tcaggactct acatcctgtc cttcactgtc atcatggtgg 1000

 ggtttatcct gtactgctcc acccctactc gcacggccga gccggctgaa 1050

 agcagcgtgc ctccagtcac cagcattggg attgacaacc tggggctgaa 1100

 gctggaggag aacctccagg agacccactc tgctgtcttg tagctggaga 1150

 agatggcgca cccatccccc accaggataa agcagagcct gctgcctgct 1200

 gaggggacac ttggggaaat agcagactca gaatggacac tctacaaccc 1250

 tgggttggat ccagtggtta ggttttagaa aggaacactg aacaaagttc 1300

 aaaagtagaa ataccaaaat agagcagaaa ccaagctaag agtgtgtttc 1350

 tgtgtttgag gaccaatatc tgttcgtgtt gaggagatga ggtgcagact 1400

 ccacactggg gtcttagagg caccggtggg aaagcaggac tggggagaga 1450

 tccaggactg agccagcctc aggccagggc gggaaagcag gctgtccagg 1500

 ctgggcttgg tggtcaggaa caggggcagc tcacggtggc tctggagtac 1550

 gtttcctctg tcagatgctt caaggttttt tttttttttt ttttttgctg 1600

 aggcagttat tgtccacagg cctttgggta cagatgaggc ctcggggctg 1650

 actgcatgtg gcagaaaacg ggtgggtcag cccttgaaaa gtcttgagat 1700

 ataagtgtga gtactataca agcattaaac tggagtgcag taaacctagg 1750

 aaccttccca caattgtttt tttgtttgtt tgagatgcag agtctagagt 1800

 gcagtggtgc aagctcagct tactgtaacc tctgcctcct ggattcaagt 1850

 gttagtagct gggattacaa aagcatgtgg ccccacgccc agctaagttt 1900

 tgtattttta gtagacatgg ggtttcacca tgttgcccag gctggtcttg 1950

 acctcccgac ctcaagtgat ctgcctgccc cgacctccca aagtgctggg 2000

 attacaggct tgagccaccg tgccaggcct gttttgtttg tttttgtaga 2050

 gagatggggt ttcgccatgt tgcccaggct aatctcaaat tcctgagcta 2100

 aagcgatctg cccacctcgg cctccgaaag tgctaggatt acagatgtga 2150

 accactgtgc ctggcctgtt tgtttgtttg tttaaaacat ttctccatca 2200

 ctcattccag gtcccagagc aaactctctc tgctctcgga gcctgtgaca 2250

 ctggctatgt gctccacagt ttcagtccca ggtcatactc tccaacagtt 2300

 ttcagagctc catatatatg tagatgccat cctttctaaa aacttctcac 2350

 gacctcctgg aatattccta ttgatctcat tttatttagc atcagctcaa 2400

 gaaactaagt cttagtgcac agtatcacaa caaagaaaaa gctttgtttt 2450

 tataactggt aaaaacaaga aaagattctc atcaaaatga aaatataaaa 2500

 ttaatcattt ctcaccaaag agtatgcctg ggagcctcca gctgttaaaa 2550

 gacaatgcta ttactacttc ttatcaaaaa tctgtaatgc cctgtgattt 2600

 ttatgatact tcttcaatac aaagtgttaa tatgtgtcat cagtataata 2650

 acaaccaaca aaatgccact ttcagaaaac tgtatgtaaa ttttttgtaa 2700

 caatgtaaaa aagaaatggg gagtaagtgt tcacatcatt aaaaggcttt 2750

 gaattcatgg aaat 2764

<210> 3290
<211> 374
<212> PRT
<213> Homo sapien

<400> 3290
 Met Glu Ala Asp Ser Pro Ala Gly Pro Gly Ala Pro Glu Pro Leu
   1               5                  10                  15

 Ala Glu Gly Ala Ala Ala Glu Phe Ser Ser Leu Leu Arg Arg Ile
                  20                  25                  30

 Lys Gly Lys Leu Phe Thr Trp Asn Ile Leu Lys Thr Ile Ala Leu
                  35                  40                  45

 Gly Gln Thr Leu Ser Leu Cys Ile Cys Gly Thr Ala Ile Thr Ser
                  50                  55                  60

 Gln Tyr Leu Ala Glu Arg Tyr Lys Val Asn Thr Pro Met Leu Gln
                  65                  70                  75

 Ser Phe Ile Asn Tyr Cys Leu Leu Phe Leu Ile Tyr Thr Val Met
                  80                  85                  90

 Leu Ala Phe Arg Ser Gly Ser Asp Asn Leu Leu Val Ile Leu Lys
                  95                 100                 105

 Arg Lys Trp Trp Lys Tyr Ile Leu Leu Gly Leu Ala Asp Val Glu
                 110                 115                 120

 Ala Asn Tyr Val Ile Val Arg Ala Tyr Gln Tyr Thr Thr Leu Thr
                 125                 130                 135

 Ser Val Gln Leu Leu Asp Cys Phe Gly Ile Pro Val Leu Met Ala
                 140                 145                 150

 Leu Ser Trp Phe Ile Leu His Ala Arg Tyr Arg Val Ile His Phe
                 155                 160                 165

 Ile Ala Val Ala Val Cys Leu Leu Gly Val Gly Thr Met Val Gly
                 170                 175                 180

 Ala Asp Ile Leu Ala Gly Arg Glu Asp Asn Ser Gly Ser Asp Val
                 185                 190                 195

 Leu Ile Gly Asp Ile Leu Val Leu Leu Gly Ala Ser Leu Tyr Ala
                 200                 205                 210

 Ile Ser Asn Val Cys Glu Glu Tyr Ile Val Lys Lys Leu Ser Arg
                 215                 220                 225

 Gln Glu Phe Leu Gly Met Val Gly Leu Phe Gly Thr Ile Ile Ser
                 230                 235                 240

 Gly Ile Gln Leu Leu Ile Val Glu Tyr Lys Asp Ile Ala Ser Ile
                 245                 250                 255

 His Trp Asp Trp Lys Ile Ala Leu Leu Phe Val Ala Phe Ala Leu
                 260                 265                 270

 Cys Met Phe Cys Leu Tyr Ser Phe Met Pro Leu Val Ile Lys Val
                 275                 280                 285

 Thr Ser Ala Thr Ser Val Asn Leu Gly Ile Leu Thr Ala Asp Leu
                 290                 295                 300

 Tyr Ser Leu Phe Val Gly Leu Phe Leu Phe Gly Tyr Lys Phe Ser
                 305                 310                 315

 Gly Leu Tyr Ile Leu Ser Phe Thr Val Ile Met Val Gly Phe Ile
                 320                 325                 330

 Leu Tyr Cys Ser Thr Pro Thr Arg Thr Ala Glu Pro Ala Glu Ser
                 335                 340                 345

 Ser Val Pro Pro Val Thr Ser Ile Gly Ile Asp Asn Leu Gly Leu
                 350                 355                 360

 Lys Leu Glu Glu Asn Leu Gln Glu Thr His Ser Ala Val Leu
                 365                 370

<210> 3291
<211> 3082
<212> DNA
<213> Homo sapien

<400> 3291
 catttgcctt ctcgttttgg cctaaggata gagtaatgat aaaccgctta 50

 gacaacatct gtgaagcagt gttgaaaggc aaatggccag taaataggcg 100

 ccagatgttt gatttccaag gcctcatccc aggttacaca cccaccacag 150

 tggacagccc cttgcagaag aggagctttg ctgagctctc catggtcggc 200

 caagccagca ttagtgggag tgaggacatc actacgtctc ctcagttgtc 250

 aaaggaagat gccctcaacc tctctgtccc tcgccagcgg aggaggagga 300

 ggagaaaaat cgaaattgag gccgaaagag ctgccaagag gcgaaatctc 350

 atggagatgg ttgcccagct tcgagagtct caggtggtct cagaaaatgg 400

 acaagaaaaa gttgtagatt tatcaaaggc ctcaagagag gcaacaagct 450

 ctacctcaaa tttttcatct ctttcttcaa agtttatctt gcctaatgtc 500

 tcaacaccag tgtctgatgc ctttaagact caaatggaac tgctccaagc 550

 aggcctttcg cgcacaccca caaggcatct ccttaatggc tccctagtgg 600

 atggagagcc tcccatgaag aggaggcggg gaaggaggaa aaatgtggag 650

 ggacttgatc tgcttttcat gagccacaaa cggacgtcat tgagtgcaga 700

 ggatgctgag gtgaccaaag cttttgaaga agatatagag accccaccaa 750

 caagaaacat tccttctccc ggacagctgg acccagacac acggatccct 800

 gttatcaatc ttgaagatgg gactaggctg gtgggggaag atgctcctaa 850

 aaataaggat ttagttgaat ggctgaagct gcaccctact tacactgttg 900

 atatgccaag ttatgtacca aagaatgcag atgtgctgtt ttcctcattt 950

 cagaaaccga aacagaaacg acatagatgt cgaaacccta ataaattgga 1000

 tataaacact ttgacaggag aagaaagggt gcctgttgtc aataaacgaa 1050

 atgggaagaa gatgggtgga gctatggcgc ctccaatgaa ggatctaccc 1100

 aggtggctgg aagaaaatcc tgaatttgca gttgctccag actggactga 1150

 tatagttaag cagtctggtt ttgttcctga gtcgatgttt gaccgccttc 1200

 tcactgggcc tgtagtgcgg ggagagggag cgagcagaag aggaagaagg 1250

 cccaaaagtg agatcgccag agcagccgcg gccgccgctg ctgtggcctc 1300

 cacgtcaggg atcaaccctt tgctggtgaa cagcctgttt gctggaatgg 1350

 acctgacgag ccttcagaat ctccagaatc tccagtcgct ccagctggca 1400

 ggcctcatgg gcttccctcc aggactggca acagctgcca ccgccggagg 1450

 cgatgcgaag aaccctgctg ctgtgctgcc cctgatgctg ccaggaatgg 1500

 cgggcctgcc caacgtgttt ggcttgggcg ggctgttgaa taaccctctg 1550

 tcagctgcta ctggaaacac cactactgct tctagtcaag gagaaccgga 1600

 agacagcact tcaaaaggag aggagaaagg aaatgagaat gaagacgaga 1650

 acaaagactc tgagaaaagc acagatgctg tttcggctgc tgactctgcg 1700

 aatggatctg ttggtgctgc tactgccccg gctggattgc cctcaaaccc 1750

 gctagccttc aaccctttcc tcctgtccac aatggccccg ggcctcttct 1800

 acccatccat gtttctacct ccaggactgg ggggattgac gctgcctggg 1850

 ttcccagcat tggcaggact tcagaatgcc gtgggctcca gcgaagaaaa 1900

 ggctgctgac aaggctgagg gaggaccctt taaagatgga gagacccttg 1950

 aaggcagcga tgccgaggag agcctggata agactgcaga gtcctccctc 2000

 ttagaagacg aaatagcaca gggtgaagag ctagactcac ttgatggggg 2050

 ggatgaaata gaaaacaatg aaaatgatga ataaccagta ccagttccag 2100

 ttcaagtgtt taaaactttt gacaagtggt agtcctactg tttacactca 2150

 cagttaatgt tcatacctag ttttataagc tgttctgtaa catagtgtag 2200

 caaaaaaaaa agttcaagtc atgttataca ggtgtgtcaa aaggtatctt 2250

 ggtcattaag tattgtgcag tgcattattt attatcccta ggagagatga 2300

 aatttgagag gtgatcatgt ctttttaagg aaacttacat aatgctctgc 2350

 tttttttttt tctcttggta ccattggtat tataataaag agcaatttgt 2400

 aactgagtgg cactaatgga agaaagtgct gctcaaagga agtatgaagt 2450

 tatatattta attttttaat tttaattttt aatttttttg ctgtgaaggt 2500

 caagctgaaa tttaccatac atatcatact tgctcatttg tttccctttt 2550

 tgactgtatg ggggttccca cactcgtgca tacacacaca tccatacact 2600

 ctgacaatct ccacgctagt gtgaacgcct ctgtcccgag gcgcagcaat 2650

 aataaggcag ctgttgaatg tgaagggtcc ctttggaaaa ttaacctact 2700

 gggagggttc ttgccagaca gaactacagt tccattgtct cgtggtcttg 2750

 taatgcactg gtaaaaacaa aataaataga tgaataaata aagagtgaga 2800

 gaagagagaa tcaggtacct tttttaaatt aaaggacttt gttactttag 2850

 ccacaaagct aaaacagcat tacctcagct ctaaactagc cttgaagttt 2900

 acagacatga ctttgtaaat gtattgtttt tctttgttgt gatgtccttt 2950

 tatttttttc tctgaaaact gctatcatgt aagataaaat gtaaattgct 3000

 gccaactgta gtaatgatgc ttttaataaa agtgacccat gatatgcaga 3050

 gatgtaaaaa aaaaaaaaaa aaaaaaaaaa aa 3082

<210> 3292
<211> 682
<212> PRT
<213> Homo sapien

<400> 3292
 Met Ile Asn Arg Leu Asp Asn Ile Cys Glu Ala Val Leu Lys Gly
   1               5                  10                  15

 Lys Trp Pro Val Asn Arg Arg Gln Met Phe Asp Phe Gln Gly Leu
                  20                  25                  30

 Ile Pro Gly Tyr Thr Pro Thr Thr Val Asp Ser Pro Leu Gln Lys
                  35                  40                  45

 Arg Ser Phe Ala Glu Leu Ser Met Val Gly Gln Ala Ser Ile Ser
                  50                  55                  60

 Gly Ser Glu Asp Ile Thr Thr Ser Pro Gln Leu Ser Lys Glu Asp
                  65                  70                  75

 Ala Leu Asn Leu Ser Val Pro Arg Gln Arg Arg Arg Arg Arg Arg
                  80                  85                  90

 Lys Ile Glu Ile Glu Ala Glu Arg Ala Ala Lys Arg Arg Asn Leu
                  95                 100                 105

 Met Glu Met Val Ala Gln Leu Arg Glu Ser Gln Val Val Ser Glu
                 110                 115                 120

 Asn Gly Gln Glu Lys Val Val Asp Leu Ser Lys Ala Ser Arg Glu
                 125                 130                 135

 Ala Thr Ser Ser Thr Ser Asn Phe Ser Ser Leu Ser Ser Lys Phe
                 140                 145                 150

 Ile Leu Pro Asn Val Ser Thr Pro Val Ser Asp Ala Phe Lys Thr
                 155                 160                 165

 Gln Met Glu Leu Leu Gln Ala Gly Leu Ser Arg Thr Pro Thr Arg
                 170                 175                 180

 His Leu Leu Asn Gly Ser Leu Val Asp Gly Glu Pro Pro Met Lys
                 185                 190                 195

 Arg Arg Arg Gly Arg Arg Lys Asn Val Glu Gly Leu Asp Leu Leu
                 200                 205                 210

 Phe Met Ser His Lys Arg Thr Ser Leu Ser Ala Glu Asp Ala Glu
                 215                 220                 225

 Val Thr Lys Ala Phe Glu Glu Asp Ile Glu Thr Pro Pro Thr Arg
                 230                 235                 240

 Asn Ile Pro Ser Pro Gly Gln Leu Asp Pro Asp Thr Arg Ile Pro
                 245                 250                 255

 Val Ile Asn Leu Glu Asp Gly Thr Arg Leu Val Gly Glu Asp Ala
                 260                 265                 270

 Pro Lys Asn Lys Asp Leu Val Glu Trp Leu Lys Leu His Pro Thr
                 275                 280                 285

 Tyr Thr Val Asp Met Pro Ser Tyr Val Pro Lys Asn Ala Asp Val
                 290                 295                 300

 Leu Phe Ser Ser Phe Gln Lys Pro Lys Gln Lys Arg His Arg Cys
                 305                 310                 315

 Arg Asn Pro Asn Lys Leu Asp Ile Asn Thr Leu Thr Gly Glu Glu
                 320                 325                 330

 Arg Val Pro Val Val Asn Lys Arg Asn Gly Lys Lys Met Gly Gly
                 335                 340                 345

 Ala Met Ala Pro Pro Met Lys Asp Leu Pro Arg Trp Leu Glu Glu
                 350                 355                 360

 Asn Pro Glu Phe Ala Val Ala Pro Asp Trp Thr Asp Ile Val Lys
                 365                 370                 375

 Gln Ser Gly Phe Val Pro Glu Ser Met Phe Asp Arg Leu Leu Thr
                 380                 385                 390

 Gly Pro Val Val Arg Gly Glu Gly Ala Ser Arg Arg Gly Arg Arg
                 395                 400                 405

 Pro Lys Ser Glu Ile Ala Arg Ala Ala Ala Ala Ala Ala Ala Val
                 410                 415                 420

 Ala Ser Thr Ser Gly Ile Asn Pro Leu Leu Val Asn Ser Leu Phe
                 425                 430                 435

 Ala Gly Met Asp Leu Thr Ser Leu Gln Asn Leu Gln Asn Leu Gln
                 440                 445                 450

 Ser Leu Gln Leu Ala Gly Leu Met Gly Phe Pro Pro Gly Leu Ala
                 455                 460                 465

 Thr Ala Ala Thr Ala Gly Gly Asp Ala Lys Asn Pro Ala Ala Val
                 470                 475                 480

 Leu Pro Leu Met Leu Pro Gly Met Ala Gly Leu Pro Asn Val Phe
                 485                 490                 495

 Gly Leu Gly Gly Leu Leu Asn Asn Pro Leu Ser Ala Ala Thr Gly
                 500                 505                 510

 Asn Thr Thr Thr Ala Ser Ser Gln Gly Glu Pro Glu Asp Ser Thr
                 515                 520                 525

 Ser Lys Gly Glu Glu Lys Gly Asn Glu Asn Glu Asp Glu Asn Lys
                 530                 535                 540

 Asp Ser Glu Lys Ser Thr Asp Ala Val Ser Ala Ala Asp Ser Ala
                 545                 550                 555

 Asn Gly Ser Val Gly Ala Ala Thr Ala Pro Ala Gly Leu Pro Ser
                 560                 565                 570

 Asn Pro Leu Ala Phe Asn Pro Phe Leu Leu Ser Thr Met Ala Pro
                 575                 580                 585

 Gly Leu Phe Tyr Pro Ser Met Phe Leu Pro Pro Gly Leu Gly Gly
                 590                 595                 600

 Leu Thr Leu Pro Gly Phe Pro Ala Leu Ala Gly Leu Gln Asn Ala
                 605                 610                 615

 Val Gly Ser Ser Glu Glu Lys Ala Ala Asp Lys Ala Glu Gly Gly
                 620                 625                 630

 Pro Phe Lys Asp Gly Glu Thr Leu Glu Gly Ser Asp Ala Glu Glu
                 635                 640                 645

 Ser Leu Asp Lys Thr Ala Glu Ser Ser Leu Leu Glu Asp Glu Ile
                 650                 655                 660

 Ala Gln Gly Glu Glu Leu Asp Ser Leu Asp Gly Gly Asp Glu Ile
                 665                 670                 675

 Glu Asn Asn Glu Asn Asp Glu
                 680

<210> 3293
<211> 1520
<212> DNA
<213> Homo sapien

<400> 3293
 ggcacgaggc cgagcctagt gcctcccacg cccggcggcc gcgagccggg 50

 gtccgcgagg gcggagtggg gcgcggcagc caggaacccg actacgaatc 100

 ccagggtgcg ggcgggcgga gcgaggaggg acgctgggcc tgcccggtgc 150

 gcacgggggc ggggaccggc aaggcgggac catttcccgg cataggctcc 200

 ggtgcccctg cccggctccc gccgggaagt tctaggccgc cgcacagaaa 250

 gccctgccct ccacgccggg tctctggagc gccctgggtt gcccggccgg 300

 tccctgccgc tgacttgttg acactgcgag cactcagtcc ctcccgcgcg 350

 cctcctcccc gcccgccccg ccgctcctcc tccctgtaac atgccatagt 400

 gcgcctgcga ccacacggcc ggggcgctag cgttcgcctt cagccaccat 450

 ggggaatggg atgaacaaga tcctgcccgg cctgtacatc ggcaacttca 500

 aagatgccag agacgcggaa caattgagca agaacaaggt gacacatatt 550

 ctgtctgtcc atgatagtgc caggcctatg ttggagggag ttaaatacct 600

 gtgcatccca gcagcggatt caccatctca aaacctgaca agacatttca 650

 aagaaagtat taaattcatt cacgagtgcc ggctccgcgg tgagagctgc 700

 cttgtacact gcctggccgg ggtctccagg agcgtgacac tggtgatcgc 750

 atacatcatg accgtcactg actttggctg ggaggatgcc ctgcacaccg 800

 tgcgtgctgg gagatcctgt gccaacccca acgtgggctt ccagagacag 850

 ctccaggagt ttgagaagca tgaggtccat cagtatcggc agtggctgaa 900

 ggaagaatat ggagagagcc ctttgcagga tgcagaagaa gccaaaaaca 950

 ttctggccgc tccaggaatt ctgaagttct gggcctttct cagaagactg 1000

 taatgtacct gaagtttctg aaatattgca aacccacaga gtttaggctg 1050

 gtgctgccaa aaagaaaagc aacatagagt ttaagtatcc agtagtgatt 1100

 tgtaaacttg tttttcattt gaagctgaat atatacgtag tcatgtttat 1150

 gttgagaact aaggatattc tttagcaaga gaaaatattt tccccttatc 1200

 cccactgctg tggaggtttc tgtacctcgc ttggatgcct gtaaggatcc 1250

 cgggagcctt gccgcactgc cttgtgggtg gcttggcgct cgtgattgct 1300

 tcctgtgaac gcctcccaag gacgagccca gtgtagttgt gtggcgtgaa 1350

 ctctgcccgt gtgttctcaa attccccagc ttgggaaata gcccttggtg 1400

 tgggttttat ctctggtttg tgttctccgt ggtggaattg accgaaagct 1450

 ctatgttttc gttaataaag ggcaacttag ccaagtttaa aaaaaaaaaa 1500

 aaaaaaaaaa aaaaaaaaaa 1520

<210> 3294
<211> 184
<212> PRT
<213> Homo sapien

<400> 3294
 Met Gly Asn Gly Met Asn Lys Ile Leu Pro Gly Leu Tyr Ile Gly
   1               5                  10                  15

 Asn Phe Lys Asp Ala Arg Asp Ala Glu Gln Leu Ser Lys Asn Lys
                  20                  25                  30

 Val Thr His Ile Leu Ser Val His Asp Ser Ala Arg Pro Met Leu
                  35                  40                  45

 Glu Gly Val Lys Tyr Leu Cys Ile Pro Ala Ala Asp Ser Pro Ser
                  50                  55                  60

 Gln Asn Leu Thr Arg His Phe Lys Glu Ser Ile Lys Phe Ile His
                  65                  70                  75

 Glu Cys Arg Leu Arg Gly Glu Ser Cys Leu Val His Cys Leu Ala
                  80                  85                  90

 Gly Val Ser Arg Ser Val Thr Leu Val Ile Ala Tyr Ile Met Thr
                  95                 100                 105

 Val Thr Asp Phe Gly Trp Glu Asp Ala Leu His Thr Val Arg Ala
                 110                 115                 120

 Gly Arg Ser Cys Ala Asn Pro Asn Val Gly Phe Gln Arg Gln Leu
                 125                 130                 135

 Gln Glu Phe Glu Lys His Glu Val His Gln Tyr Arg Gln Trp Leu
                 140                 145                 150

 Lys Glu Glu Tyr Gly Glu Ser Pro Leu Gln Asp Ala Glu Glu Ala
                 155                 160                 165

 Lys Asn Ile Leu Ala Ala Pro Gly Ile Leu Lys Phe Trp Ala Phe
                 170                 175                 180

 Leu Arg Arg Leu


<210> 3295
<211> 5227
<212> DNA
<213> Homo sapien

<400> 3295
 gctgttggct gggctcggga gggaacgctc caggtaaagc gctgggggag 50

 gaagcgacgc cgaggagcta cggtttcctc cagaggtctc cgcccctctg 100

 cccctatatt cccagagctc gagtctgatc cgggccttgc cgggcaccct 150

 ggaaaggcgg gggtgatagt acagatggag acgcaactgc agagcatttt 200

 cgaagaggtg gtgaaaacgg aagttataga agaggctttt cctggcatgt 250

 ttatggatac tcctgaagat gagaaaacaa aactaattag ctgtttgggg 300

 gccttcagac agttttgggg tggtctttct caggagtctc atgaacagtg 350

 tatccagtgg attgttaagt ttattcatgg tcagcatagt cctaaaagaa 400

 tttcttttct ttatgactgc ttagcaatgg cagttgagac tggtctcctt 450

 ccacccaggc tggtttgtga atccctgata aactctgaca ctcttgagtg 500

 ggaaagaaca cagctttggg ccttaacatt taaactggtt cggaaaataa 550

 ttgggggagt ggattacaag ggtgttcgag atctcttaaa agtgattttg 600

 gagaagattt tgacaattcc taatacagtg agctctgctg ttgtacagca 650

 gcttctggca gcaagagagg ttatagcata tatcttggaa agaaatgcct 700

 gcttattacc agcctatttt gcagtcactg agatcaggaa actgtatcct 750

 gaaggcaaac ttccacactg gttacttgga aacctagtat cagactttgt 800

 ggataccttc aggcccacag caaggataaa ctccatttgt ggtcgctgta 850

 gtcttctgcc agttgtaaat aattcgggtg ccatttgtaa ttcatggaaa 900

 ctggatcctg ctactcttcg ttttcctttg aaaggccttt tgccatatga 950

 taaggatctg tttgaaccac agactgcttt gttgagatat gtattggagc 1000

 agccttattc cagggatatg gtctgcaata tgctaggttt aaataagcag 1050

 cacaagcagc gctgccctgt gctggaggac cagttggtgg atctggttgt 1100

 ttatgccatg gagcgatctg agaccgagga gaagtttgac gatgggggaa 1150

 caagccaact cctgtggcag catctctcaa gtcagctcat tttctttgtg 1200

 cttttccagt ttgcaagttt tccacatatg gtgctttctc ttcatcagaa 1250

 gttagcaggg cgaggactga ttaaaggcag agatcatctt atgtgggttc 1300

 tcctgcaatt catttctgga agtattcaga aaaatgcact agctgatttt 1350

 ctccctgtga tgaagctctt cgacttgcta tacccagaaa aagaatatat 1400

 cccagttcct gatattaaca aaccccagtc aacccatgcc tttgcaatga 1450

 cctgtatttg gattcatctc aatagaaaag ctcaaaatga caactccaag 1500

 ctacagattc caatacctca ttccctaaga cttcaccatg agttcctgca 1550

 gcagagtcta agaaataaaa gtttacagat gaatgactat aagattgctc 1600

 tattgtgtaa tgcatactct acaaattcag aatgttttac attacccatg 1650

 ggagctctgg tagaaactat ttatggaaat ggaattatga ggatacctct 1700

 ccctggaaca aactgtatgg cttcaggatc tattaccccc ttacctatga 1750

 acctcctgga ttcactgaca gttcatgcca aaatgagcct tattcacagc 1800

 attgcaacca gggtgataaa acttgctcat gcaaagtcca gtgtggcctt 1850

 ggctccagcc ctagtggaaa cttacagtcg tttattggtc tatatggaaa 1900

 tagagtcttt gggcatcaaa ggatttatca gtcagctttt gccaactgtt 1950

 ttcaaatcac atgcatgggg gatcttacac acactccttg agatgtttag 2000

 ctaccggatg catcatattc agcctcatta cagagttcag ctcctgagtc 2050

 atcttcatac tttggctgca gttgcacaaa caaaccagaa ccagctccat 2100

 ctttgtgtcg agagcactgc tctcaggctt ataacagcat taggtagctc 2150

 agaggtacaa ccgcagttta cacgcttcct tagtgatccc aaaacagtgc 2200

 tctcagcaga atctgaagaa ctgaaccgag ccttgatatt gaccttggct 2250

 agagcaactc atgtaacaga tttttttaca ggctctgatt caattcaggg 2300

 aacttggtgt aaagacatac ttcagaccat catgagtttc actcctcata 2350

 attgggcttc acacaccctg agctgttttc caggcccact acaggcattc 2400

 ttcaaacaaa ataatgtgcc tcaggaaagc cgttttaatc tgaaaaaaaa 2450

 tgtggaggag gagtatagga agtggaagtc aatgagcaac gaaaacgaca 2500

 ttattaccca cttctctatg cagggctccc ctcctctctt tctttgtctt 2550

 ctctggaaaa tgctcttgga aacagatcat attaatcaga ttggctatag 2600

 agtattagag agaattggag ccagggcctt ggtagcccat gtgaggacat 2650

 ttgcagattt cctggtatat gagttttcta catcagcagg gggtcagcaa 2700

 ctcaataaat gcattgaaat tcttaatgac atggtatgga agtataacat 2750

 tgttacactg gacagattaa ttctctgcct ggccatgcgt agtcacgaag 2800

 gaaatgaagc ccaggtttgt tatttcataa ttcagttgct gttactcaaa 2850

 ccaaacgatt ttagaaatcg agtaagtgac tttgtgaagg aaaattcccc 2900

 agagcactgg ttacagaatg actggcacac caagcacatg aattatcaca 2950

 agaaatatcc agagaagttg tattttgagg gcctcgcgga acaggtggat 3000

 cctcctgtac agatccagtc tccctatctg cccatctatt ttgggaatgt 3050

 gtgtcttcga ttccttccag tatttgatat agtaatccac agatttttag 3100

 agttgcttcc ggtatccaaa tcactggaga ctctactgga tcatctagga 3150

 ggcttatata aatttcatga tcgtccagtg acttatctgt ataacactct 3200

 gcactattat gaaatgcacc tgagagaccg cgcatttctc aaacgaaaac 3250

 tcgtccatgc gatcattggc tctctgaagg ataatcgacc gcagggctgg 3300

 tgtctaagtg acacttacct gaaatgcgct atgaatgcac gagaggaaaa 3350

 tccttgggtt ccagatgaca cctactattg cagattgatt ggcagactag 3400

 tcgatacgat ggctggcaaa tctcctggtc cctttccaaa ctgtgactgg 3450

 agattcaatg agtttcccaa cccagctgcc catgctctcc atgttacttg 3500

 tgtggagctc atggccttgg cagtttcagg caaagaagtt gggaatgccc 3550

 ttctaaatgt tgtcctaaaa agtcagcctt tagtgccaag agagaacatt 3600

 acagcatgga tgaatgcaat tggtttgatc atcactgccc taccagagcc 3650

 atattggatt gttcttcatg atcgaattgt gagtgtcatc agcagcccca 3700

 gcttgacgtc tgaaacagag tgggttggct atccattccg cctctttgat 3750

 ttcactgcct gtcatcagtc ctactctgag atgagttgta gctatacgtt 3800

 agctcttgca catgctgtgt ggcaccattc tagcatcgga caactttctc 3850

 tcattccaaa gtttcttact gaagtacttc ttcctatagt gaagaccgaa 3900

 ttccagttgc tttatgtata ccatcttgtt ggaccatttt tacaaagatt 3950

 tcagcaagag agaactcgtt gtatgataga gattggtgtg gcgttttatg 4000

 acatgctgct gaatgttgac cagtgtagca cccatttaaa ttacatggat 4050

 cccatctgtg acttcctcta tcacatgaag tatatgttta ctggtgacag 4100

 cgtgaaagag caagtagaga agattatctg taacttaaaa ccagctttaa 4150

 aacttcgtct tcgattcatc acacacatta gcaagatgga gccagctgca 4200

 gtgcctccac aagccatgaa cagtgggtct ccagcacctc agtctaatca 4250

 ggtgcccgtg tctttaccag taactcagtg aagccagact gtactgtgga 4300

 gaaagtagaa atatatccgt ctttgagagt ggactcaaac cttttaaatc 4350

 tgaatgcgat cacactgtag tgatatagta gaagcagtga tgatattcag 4400

 attgttttat tttgattcaa atgatgaatc tgttgacacc ttataactcc 4450

 catctcccta tctatatttt tgtctctaag agatcaagta agatacatgt 4500

 tgttcatatt cataacaact tattagagct atgtaggaac atagaggtat 4550

 ctgtgatcaa atgacttgtc attggcactt tcagtctttc ctattctagc 4600

 cgttgttttt gtttgtattt tttattatta atgacatatt tagtcttcag 4650

 atatattatt ttaaaggcac cacacatgta aaacagttat tacaaatatt 4700

 ttatacataa atctcttggt agattttcag aataatagag atttatatca 4750

 agaaaaggaa tctagatttt gttgcattgt aggagcaaac aaggcttcat 4800

 attcttttta aaatgacttg aaattttatt ataaatttcc atagtttcta 4850

 tcaaggtcaa ctggcagttt tattaccttt gctatggact tgaacttact 4900

 gtataaaatt agttggaagc catgtaagaa aataacatct gaaaattctt 4950

 gaacttaaaa tcatgcttaa atggttgatt ctccaatttc tttttttaaa 5000

 aataagttaa ttgcttttgc aggttgacac tctcacctga cagatgatgt 5050

 aattcttcaa tttttataat cttaaaattt ttaaatttta tatttgtaaa 5100

 tacagtacac attttatttc ttggattttg agagacattg ttaattttgg 5150

 gggaattggc attgcgaaag acttgaaaac taatgagtaa agtctgctga 5200

 atgaataaac cgtgtgattg tttcccg 5227

<210> 3296
<211> 1368
<212> PRT
<213> Homo sapien

<400> 3296
 Met Glu Thr Gln Leu Gln Ser Ile Phe Glu Glu Val Val Lys Thr
   1               5                  10                  15

 Glu Val Ile Glu Glu Ala Phe Pro Gly Met Phe Met Asp Thr Pro
                  20                  25                  30

 Glu Asp Glu Lys Thr Lys Leu Ile Ser Cys Leu Gly Ala Phe Arg
                  35                  40                  45

 Gln Phe Trp Gly Gly Leu Ser Gln Glu Ser His Glu Gln Cys Ile
                  50                  55                  60

 Gln Trp Ile Val Lys Phe Ile His Gly Gln His Ser Pro Lys Arg
                  65                  70                  75

 Ile Ser Phe Leu Tyr Asp Cys Leu Ala Met Ala Val Glu Thr Gly
                  80                  85                  90

 Leu Leu Pro Pro Arg Leu Val Cys Glu Ser Leu Ile Asn Ser Asp
                  95                 100                 105

 Thr Leu Glu Trp Glu Arg Thr Gln Leu Trp Ala Leu Thr Phe Lys
                 110                 115                 120

 Leu Val Arg Lys Ile Ile Gly Gly Val Asp Tyr Lys Gly Val Arg
                 125                 130                 135

 Asp Leu Leu Lys Val Ile Leu Glu Lys Ile Leu Thr Ile Pro Asn
                 140                 145                 150

 Thr Val Ser Ser Ala Val Val Gln Gln Leu Leu Ala Ala Arg Glu
                 155                 160                 165

 Val Ile Ala Tyr Ile Leu Glu Arg Asn Ala Cys Leu Leu Pro Ala
                 170                 175                 180

 Tyr Phe Ala Val Thr Glu Ile Arg Lys Leu Tyr Pro Glu Gly Lys
                 185                 190                 195

 Leu Pro His Trp Leu Leu Gly Asn Leu Val Ser Asp Phe Val Asp
                 200                 205                 210

 Thr Phe Arg Pro Thr Ala Arg Ile Asn Ser Ile Cys Gly Arg Cys
                 215                 220                 225

 Ser Leu Leu Pro Val Val Asn Asn Ser Gly Ala Ile Cys Asn Ser
                 230                 235                 240

 Trp Lys Leu Asp Pro Ala Thr Leu Arg Phe Pro Leu Lys Gly Leu
                 245                 250                 255

 Leu Pro Tyr Asp Lys Asp Leu Phe Glu Pro Gln Thr Ala Leu Leu
                 260                 265                 270

 Arg Tyr Val Leu Glu Gln Pro Tyr Ser Arg Asp Met Val Cys Asn
                 275                 280                 285

 Met Leu Gly Leu Asn Lys Gln His Lys Gln Arg Cys Pro Val Leu
                 290                 295                 300

 Glu Asp Gln Leu Val Asp Leu Val Val Tyr Ala Met Glu Arg Ser
                 305                 310                 315

 Glu Thr Glu Glu Lys Phe Asp Asp Gly Gly Thr Ser Gln Leu Leu
                 320                 325                 330

 Trp Gln His Leu Ser Ser Gln Leu Ile Phe Phe Val Leu Phe Gln
                 335                 340                 345

 Phe Ala Ser Phe Pro His Met Val Leu Ser Leu His Gln Lys Leu
                 350                 355                 360

 Ala Gly Arg Gly Leu Ile Lys Gly Arg Asp His Leu Met Trp Val
                 365                 370                 375

 Leu Leu Gln Phe Ile Ser Gly Ser Ile Gln Lys Asn Ala Leu Ala
                 380                 385                 390

 Asp Phe Leu Pro Val Met Lys Leu Phe Asp Leu Leu Tyr Pro Glu
                 395                 400                 405

 Lys Glu Tyr Ile Pro Val Pro Asp Ile Asn Lys Pro Gln Ser Thr
                 410                 415                 420

 His Ala Phe Ala Met Thr Cys Ile Trp Ile His Leu Asn Arg Lys
                 425                 430                 435

 Ala Gln Asn Asp Asn Ser Lys Leu Gln Ile Pro Ile Pro His Ser
                 440                 445                 450

 Leu Arg Leu His His Glu Phe Leu Gln Gln Ser Leu Arg Asn Lys
                 455                 460                 465

 Ser Leu Gln Met Asn Asp Tyr Lys Ile Ala Leu Leu Cys Asn Ala
                 470                 475                 480

 Tyr Ser Thr Asn Ser Glu Cys Phe Thr Leu Pro Met Gly Ala Leu
                 485                 490                 495

 Val Glu Thr Ile Tyr Gly Asn Gly Ile Met Arg Ile Pro Leu Pro
                 500                 505                 510

 Gly Thr Asn Cys Met Ala Ser Gly Ser Ile Thr Pro Leu Pro Met
                 515                 520                 525

 Asn Leu Leu Asp Ser Leu Thr Val His Ala Lys Met Ser Leu Ile
                 530                 535                 540

 His Ser Ile Ala Thr Arg Val Ile Lys Leu Ala His Ala Lys Ser
                 545                 550                 555

 Ser Val Ala Leu Ala Pro Ala Leu Val Glu Thr Tyr Ser Arg Leu
                 560                 565                 570

 Leu Val Tyr Met Glu Ile Glu Ser Leu Gly Ile Lys Gly Phe Ile
                 575                 580                 585

 Ser Gln Leu Leu Pro Thr Val Phe Lys Ser His Ala Trp Gly Ile
                 590                 595                 600

 Leu His Thr Leu Leu Glu Met Phe Ser Tyr Arg Met His His Ile
                 605                 610                 615

 Gln Pro His Tyr Arg Val Gln Leu Leu Ser His Leu His Thr Leu
                 620                 625                 630

 Ala Ala Val Ala Gln Thr Asn Gln Asn Gln Leu His Leu Cys Val
                 635                 640                 645

 Glu Ser Thr Ala Leu Arg Leu Ile Thr Ala Leu Gly Ser Ser Glu
                 650                 655                 660

 Val Gln Pro Gln Phe Thr Arg Phe Leu Ser Asp Pro Lys Thr Val
                 665                 670                 675

 Leu Ser Ala Glu Ser Glu Glu Leu Asn Arg Ala Leu Ile Leu Thr
                 680                 685                 690

 Leu Ala Arg Ala Thr His Val Thr Asp Phe Phe Thr Gly Ser Asp
                 695                 700                 705

 Ser Ile Gln Gly Thr Trp Cys Lys Asp Ile Leu Gln Thr Ile Met
                 710                 715                 720

 Ser Phe Thr Pro His Asn Trp Ala Ser His Thr Leu Ser Cys Phe
                 725                 730                 735

 Pro Gly Pro Leu Gln Ala Phe Phe Lys Gln Asn Asn Val Pro Gln
                 740                 745                 750

 Glu Ser Arg Phe Asn Leu Lys Lys Asn Val Glu Glu Glu Tyr Arg
                 755                 760                 765

 Lys Trp Lys Ser Met Ser Asn Glu Asn Asp Ile Ile Thr His Phe
                 770                 775                 780

 Ser Met Gln Gly Ser Pro Pro Leu Phe Leu Cys Leu Leu Trp Lys
                 785                 790                 795

 Met Leu Leu Glu Thr Asp His Ile Asn Gln Ile Gly Tyr Arg Val
                 800                 805                 810

 Leu Glu Arg Ile Gly Ala Arg Ala Leu Val Ala His Val Arg Thr
                 815                 820                 825

 Phe Ala Asp Phe Leu Val Tyr Glu Phe Ser Thr Ser Ala Gly Gly
                 830                 835                 840

 Gln Gln Leu Asn Lys Cys Ile Glu Ile Leu Asn Asp Met Val Trp
                 845                 850                 855

 Lys Tyr Asn Ile Val Thr Leu Asp Arg Leu Ile Leu Cys Leu Ala
                 860                 865                 870

 Met Arg Ser His Glu Gly Asn Glu Ala Gln Val Cys Tyr Phe Ile
                 875                 880                 885

 Ile Gln Leu Leu Leu Leu Lys Pro Asn Asp Phe Arg Asn Arg Val
                 890                 895                 900

 Ser Asp Phe Val Lys Glu Asn Ser Pro Glu His Trp Leu Gln Asn
                 905                 910                 915

 Asp Trp His Thr Lys His Met Asn Tyr His Lys Lys Tyr Pro Glu
                 920                 925                 930

 Lys Leu Tyr Phe Glu Gly Leu Ala Glu Gln Val Asp Pro Pro Val
                 935                 940                 945

 Gln Ile Gln Ser Pro Tyr Leu Pro Ile Tyr Phe Gly Asn Val Cys
                 950                 955                 960

 Leu Arg Phe Leu Pro Val Phe Asp Ile Val Ile His Arg Phe Leu
                 965                 970                 975

 Glu Leu Leu Pro Val Ser Lys Ser Leu Glu Thr Leu Leu Asp His
                 980                 985                 990

 Leu Gly Gly Leu Tyr Lys Phe His Asp Arg Pro Val Thr Tyr Leu
                 995                1000                1005

 Tyr Asn Thr Leu His Tyr Tyr Glu Met His Leu Arg Asp Arg Ala
                1010                1015                1020

 Phe Leu Lys Arg Lys Leu Val His Ala Ile Ile Gly Ser Leu Lys
                1025                1030                1035

 Asp Asn Arg Pro Gln Gly Trp Cys Leu Ser Asp Thr Tyr Leu Lys
                1040                1045                1050

 Cys Ala Met Asn Ala Arg Glu Glu Asn Pro Trp Val Pro Asp Asp
                1055                1060                1065

 Thr Tyr Tyr Cys Arg Leu Ile Gly Arg Leu Val Asp Thr Met Ala
                1070                1075                1080

 Gly Lys Ser Pro Gly Pro Phe Pro Asn Cys Asp Trp Arg Phe Asn
                1085                1090                1095

 Glu Phe Pro Asn Pro Ala Ala His Ala Leu His Val Thr Cys Val
                1100                1105                1110

 Glu Leu Met Ala Leu Ala Val Ser Gly Lys Glu Val Gly Asn Ala
                1115                1120                1125

 Leu Leu Asn Val Val Leu Lys Ser Gln Pro Leu Val Pro Arg Glu
                1130                1135                1140

 Asn Ile Thr Ala Trp Met Asn Ala Ile Gly Leu Ile Ile Thr Ala
                1145                1150                1155

 Leu Pro Glu Pro Tyr Trp Ile Val Leu His Asp Arg Ile Val Ser
                1160                1165                1170

 Val Ile Ser Ser Pro Ser Leu Thr Ser Glu Thr Glu Trp Val Gly
                1175                1180                1185

 Tyr Pro Phe Arg Leu Phe Asp Phe Thr Ala Cys His Gln Ser Tyr
                1190                1195                1200

 Ser Glu Met Ser Cys Ser Tyr Thr Leu Ala Leu Ala His Ala Val
                1205                1210                1215

 Trp His His Ser Ser Ile Gly Gln Leu Ser Leu Ile Pro Lys Phe
                1220                1225                1230

 Leu Thr Glu Val Leu Leu Pro Ile Val Lys Thr Glu Phe Gln Leu
                1235                1240                1245

 Leu Tyr Val Tyr His Leu Val Gly Pro Phe Leu Gln Arg Phe Gln
                1250                1255                1260

 Gln Glu Arg Thr Arg Cys Met Ile Glu Ile Gly Val Ala Phe Tyr
                1265                1270                1275

 Asp Met Leu Leu Asn Val Asp Gln Cys Ser Thr His Leu Asn Tyr
                1280                1285                1290

 Met Asp Pro Ile Cys Asp Phe Leu Tyr His Met Lys Tyr Met Phe
                1295                1300                1305

 Thr Gly Asp Ser Val Lys Glu Gln Val Glu Lys Ile Ile Cys Asn
                1310                1315                1320

 Leu Lys Pro Ala Leu Lys Leu Arg Leu Arg Phe Ile Thr His Ile
                1325                1330                1335

 Ser Lys Met Glu Pro Ala Ala Val Pro Pro Gln Ala Met Asn Ser
                1340                1345                1350

 Gly Ser Pro Ala Pro Gln Ser Asn Gln Val Pro Val Ser Leu Pro
                1355                1360                1365

 Val Thr Gln


<210> 3297
<211> 3216
<212> DNA
<213> Homo sapien

<400> 3297
 gcggacggtg agtggggatg gactggagtt gaagagctcg agatgaaggg 50

 cttgagggcg tgtgttattt gttttcttca agcatttggt cgagattaag 100

 aattaaaaat gtcatccaaa caagaaataa tgagtgacca gcggtttaga 150

 cgggttgcaa aggacccgag attttgggaa atgccagaaa aggatcgaaa 200

 agtcaaaatt gacaagagat ttcgagccat gtttcatgac aagaagttca 250

 agttgaacta tgccgtggat aaaagagggc gccccattag ccatagcact 300

 acagaggatt tgaagcgttt ttacgacctt tcagattctg attccaatct 350

 ctctggtgaa gatagcaaag cattgagtca aaagaaaata aagaagaaaa 400

 aaacccagac taaaaaagaa atcgattcaa aaaatctagt tgagaaaaag 450

 aaagaaacca agaaggctaa tcacaagggt tctgaaaata aaactgattt 500

 agataattct ataggaatta aaaaaatgaa aacctcatgt aaatttaaga 550

 tagattcaaa cataagtccg aagaaggata gcaaagaatt tacacaaaaa 600

 aataagaaag agaaaaaaaa cattgttcaa catactacag actcttctct 650

 cgaagaaaaa caaaggacat tagactcagg cacctctgaa attgtgaaat 700

 ctcccagaat cgagtgttct aagacaagaa gagaaatgca atcagtggtt 750

 caactcataa tgacaagaga cagtgatggt tatgaaaact caacagatgg 800

 tgaaatgtgt gacaaagatg ctctggagga agattcagaa agcgttagtg 850

 aaataggaag tgatgaggaa tctgaaaatg aaattacaag tgttggtaga 900

 gcttcaggtg atgacgatgg aagtgaagat gatgaagagg aggatgaaga 950

 tgaagaggag gatgaagatg aggatagtga ggatgatgat aaaagtgaca 1000

 gtggccctga tcttgcaagg ggtaaaggaa atatagaaac tagttctgaa 1050

 gatgaagatg atacggcaga tttgtttcca gaagaatctg gttttgagca 1100

 tgcttggaga gaattagata aagatgctcc tcgtgctgat gagattacac 1150

 gtcgattagc agtttgtaac atggactggg atagattaaa ggcaaaagat 1200

 ttgctggctc tgttcaattc atttaaaccc aaaggaggtg taatattttc 1250

 cgtcaagata tatccttcag aatttggaaa ggagaggatg aaggaagagc 1300

 aagttcaagg accagtagag ctattaagta ttcctgaaga tgccccagaa 1350

 aaagactgga cgtctagaga aaaattgaga gattatcaat tcaaacgact 1400

 gaagtactat tatgcagtag tagactgtga ttctccggaa acagctagta 1450

 aaatttatga ggattgtgat ggcctggaat ttgaaagtag ttgttctttc 1500

 atagatctaa ggtttatacc agatgatatt acttttgatg atgagcctaa 1550

 ggatgtagcc tcagaagtga atttaacagc atataaacca aaatatttca 1600

 cttctgctgc aatgggaaca tcaacggtgg aaatcacttg ggatgagact 1650

 gatcatgaaa gaattacaat gctcaacagg aagtttaaaa aggaagagct 1700

 tttggacatg gattttcaag cctacttagc ttcctctagt gaagatgaag 1750

 aggagataga agaggagcta caaggtgatg atggagtcaa tgtagaagaa 1800

 gatgggaaaa caaagaaaag tcagaaggat gatgaagaac aaattgctaa 1850

 atacaggcag ctcttgcagg ttattcaaga aaaagaaaag aaaggcaaag 1900

 aaaatgatat ggaaatggaa attaaatggg ttccaggtct taaagaaagt 1950

 gcagaagaga tggtcaaaaa caaattggaa ggaaaggata aactgacccc 2000

 ttgggaacaa tttttagaga agaagaaaga gaaaaaaaga ctgaaaagga 2050

 aacagaaggc tcttgctgaa gaggccagtg aagaggaact tccctctgat 2100

 gttgatttga atgacccata ctttgctgaa gaagttaaac aaataggtat 2150

 aaataaaaaa tcggtaaaat ctgcaaaaga tggcacatct ccagaagaag 2200

 aaattgaaat agaaagacaa aaggctgaaa tggctttgct tatgatggat 2250

 gaggacgagg acagtaagaa acacttcaat tacaacaaga ttgtggagca 2300

 ccagaatctg agcaaaaaga agaaaaagca gctcatgaaa aagaaggaat 2350

 taatagagga tgactttgag gtaaatgtta acgatgcacg gtttcaggca 2400

 atgtacactt cccacttgtt caatttggac ccctcagatc ccaatttcaa 2450

 gaaaacaaaa gctatggaaa aaatccttga ggagaaggcc cggcaaagag 2500

 aacggaaaga acaagaactt actcaggcaa taaagaaaaa agagagtgag 2550

 attgaaaagg aatcacaaag gaagtccatt gatcctgctt tgtcaatgtt 2600

 gattaaatct ataaaaacca aaacagagca gtttcaagca agaaaaaagc 2650

 aaaaagtcaa ataactggat gttacttatt tttgaactga atacatcttt 2700

 tcctaaaatg tacaaaaata ataggaggga atatttattg ggaacaaagc 2750

 tatctttcaa gaacatgaat aaaatctttt tctggacata gtaaaatttt 2800

 tctccataaa taattgtact taattgtgga tgactgacaa atttttattg 2850

 tatattccta cagatcagtc ataattaaat tacctgcatt atagggttta 2900

 taaaattttt atattttaca atgttcagtt ctaactagtg gaaagttact 2950

 ctagcttttt aaaaggctgt ttacaattct gtgtaaaaat agagcagtat 3000

 ctactcaagt ttgtgtaaat gttagggata atttgaaaaa tatatatatt 3050

 taatacatta atttctctgg aagcaggagg catgtttaaa taactattaa 3100

 aataatttat ttttctagcc ataaaggatg gaagtcaaga actttttgtt 3150

 gtttagtcat gttaagtata gtttatgaaa ttaacttgta aataaaagtg 3200

 taaaatattt tcatta 3216

<210> 3298
<211> 851
<212> PRT
<213> Homo sapien

<400> 3298
 Met Ser Ser Lys Gln Glu Ile Met Ser Asp Gln Arg Phe Arg Arg
   1               5                  10                  15

 Val Ala Lys Asp Pro Arg Phe Trp Glu Met Pro Glu Lys Asp Arg
                  20                  25                  30

 Lys Val Lys Ile Asp Lys Arg Phe Arg Ala Met Phe His Asp Lys
                  35                  40                  45

 Lys Phe Lys Leu Asn Tyr Ala Val Asp Lys Arg Gly Arg Pro Ile
                  50                  55                  60

 Ser His Ser Thr Thr Glu Asp Leu Lys Arg Phe Tyr Asp Leu Ser
                  65                  70                  75

 Asp Ser Asp Ser Asn Leu Ser Gly Glu Asp Ser Lys Ala Leu Ser
                  80                  85                  90

 Gln Lys Lys Ile Lys Lys Lys Lys Thr Gln Thr Lys Lys Glu Ile
                  95                 100                 105

 Asp Ser Lys Asn Leu Val Glu Lys Lys Lys Glu Thr Lys Lys Ala
                 110                 115                 120

 Asn His Lys Gly Ser Glu Asn Lys Thr Asp Leu Asp Asn Ser Ile
                 125                 130                 135

 Gly Ile Lys Lys Met Lys Thr Ser Cys Lys Phe Lys Ile Asp Ser
                 140                 145                 150

 Asn Ile Ser Pro Lys Lys Asp Ser Lys Glu Phe Thr Gln Lys Asn
                 155                 160                 165

 Lys Lys Glu Lys Lys Asn Ile Val Gln His Thr Thr Asp Ser Ser
                 170                 175                 180

 Leu Glu Glu Lys Gln Arg Thr Leu Asp Ser Gly Thr Ser Glu Ile
                 185                 190                 195

 Val Lys Ser Pro Arg Ile Glu Cys Ser Lys Thr Arg Arg Glu Met
                 200                 205                 210

 Gln Ser Val Val Gln Leu Ile Met Thr Arg Asp Ser Asp Gly Tyr
                 215                 220                 225

 Glu Asn Ser Thr Asp Gly Glu Met Cys Asp Lys Asp Ala Leu Glu
                 230                 235                 240

 Glu Asp Ser Glu Ser Val Ser Glu Ile Gly Ser Asp Glu Glu Ser
                 245                 250                 255

 Glu Asn Glu Ile Thr Ser Val Gly Arg Ala Ser Gly Asp Asp Asp
                 260                 265                 270

 Gly Ser Glu Asp Asp Glu Glu Glu Asp Glu Asp Glu Glu Glu Asp
                 275                 280                 285

 Glu Asp Glu Asp Ser Glu Asp Asp Asp Lys Ser Asp Ser Gly Pro
                 290                 295                 300

 Asp Leu Ala Arg Gly Lys Gly Asn Ile Glu Thr Ser Ser Glu Asp
                 305                 310                 315

 Glu Asp Asp Thr Ala Asp Leu Phe Pro Glu Glu Ser Gly Phe Glu
                 320                 325                 330

 His Ala Trp Arg Glu Leu Asp Lys Asp Ala Pro Arg Ala Asp Glu
                 335                 340                 345

 Ile Thr Arg Arg Leu Ala Val Cys Asn Met Asp Trp Asp Arg Leu
                 350                 355                 360

 Lys Ala Lys Asp Leu Leu Ala Leu Phe Asn Ser Phe Lys Pro Lys
                 365                 370                 375

 Gly Gly Val Ile Phe Ser Val Lys Ile Tyr Pro Ser Glu Phe Gly
                 380                 385                 390

 Lys Glu Arg Met Lys Glu Glu Gln Val Gln Gly Pro Val Glu Leu
                 395                 400                 405

 Leu Ser Ile Pro Glu Asp Ala Pro Glu Lys Asp Trp Thr Ser Arg
                 410                 415                 420

 Glu Lys Leu Arg Asp Tyr Gln Phe Lys Arg Leu Lys Tyr Tyr Tyr
                 425                 430                 435

 Ala Val Val Asp Cys Asp Ser Pro Glu Thr Ala Ser Lys Ile Tyr
                 440                 445                 450

 Glu Asp Cys Asp Gly Leu Glu Phe Glu Ser Ser Cys Ser Phe Ile
                 455                 460                 465

 Asp Leu Arg Phe Ile Pro Asp Asp Ile Thr Phe Asp Asp Glu Pro
                 470                 475                 480

 Lys Asp Val Ala Ser Glu Val Asn Leu Thr Ala Tyr Lys Pro Lys
                 485                 490                 495

 Tyr Phe Thr Ser Ala Ala Met Gly Thr Ser Thr Val Glu Ile Thr
                 500                 505                 510

 Trp Asp Glu Thr Asp His Glu Arg Ile Thr Met Leu Asn Arg Lys
                 515                 520                 525

 Phe Lys Lys Glu Glu Leu Leu Asp Met Asp Phe Gln Ala Tyr Leu
                 530                 535                 540

 Ala Ser Ser Ser Glu Asp Glu Glu Glu Ile Glu Glu Glu Leu Gln
                 545                 550                 555

 Gly Asp Asp Gly Val Asn Val Glu Glu Asp Gly Lys Thr Lys Lys
                 560                 565                 570

 Ser Gln Lys Asp Asp Glu Glu Gln Ile Ala Lys Tyr Arg Gln Leu
                 575                 580                 585

 Leu Gln Val Ile Gln Glu Lys Glu Lys Lys Gly Lys Glu Asn Asp
                 590                 595                 600

 Met Glu Met Glu Ile Lys Trp Val Pro Gly Leu Lys Glu Ser Ala
                 605                 610                 615

 Glu Glu Met Val Lys Asn Lys Leu Glu Gly Lys Asp Lys Leu Thr
                 620                 625                 630

 Pro Trp Glu Gln Phe Leu Glu Lys Lys Lys Glu Lys Lys Arg Leu
                 635                 640                 645

 Lys Arg Lys Gln Lys Ala Leu Ala Glu Glu Ala Ser Glu Glu Glu
                 650                 655                 660

 Leu Pro Ser Asp Val Asp Leu Asn Asp Pro Tyr Phe Ala Glu Glu
                 665                 670                 675

 Val Lys Gln Ile Gly Ile Asn Lys Lys Ser Val Lys Ser Ala Lys
                 680                 685                 690

 Asp Gly Thr Ser Pro Glu Glu Glu Ile Glu Ile Glu Arg Gln Lys
                 695                 700                 705

 Ala Glu Met Ala Leu Leu Met Met Asp Glu Asp Glu Asp Ser Lys
                 710                 715                 720

 Lys His Phe Asn Tyr Asn Lys Ile Val Glu His Gln Asn Leu Ser
                 725                 730                 735

 Lys Lys Lys Lys Lys Gln Leu Met Lys Lys Lys Glu Leu Ile Glu
                 740                 745                 750

 Asp Asp Phe Glu Val Asn Val Asn Asp Ala Arg Phe Gln Ala Met
                 755                 760                 765

 Tyr Thr Ser His Leu Phe Asn Leu Asp Pro Ser Asp Pro Asn Phe
                 770                 775                 780

 Lys Lys Thr Lys Ala Met Glu Lys Ile Leu Glu Glu Lys Ala Arg
                 785                 790                 795

 Gln Arg Glu Arg Lys Glu Gln Glu Leu Thr Gln Ala Ile Lys Lys
                 800                 805                 810

 Lys Glu Ser Glu Ile Glu Lys Glu Ser Gln Arg Lys Ser Ile Asp
                 815                 820                 825

 Pro Ala Leu Ser Met Leu Ile Lys Ser Ile Lys Thr Lys Thr Glu
                 830                 835                 840

 Gln Phe Gln Ala Arg Lys Lys Gln Lys Val Lys
                 845                 850

<210> 3299
<211> 796
<212> DNA
<213> Homo sapien

<400> 3299
 gggagctgcc gggagttgga gcctgcggag ttcgagacca tgctgctgtt 50

 ctgccccggc tgcgggaacg ggctgatcgt ggaggaggga caacgctgcc 100

 accgcttcgc ctgcaacacg tgcccctacg tgcacaacat cacccgcaag 150

 gtaacaaatc ggaagtaccc aaaactgaaa gaagtggatg atgtgcttgg 200

 tggagcagct gcctgggaga atgttgactc tactgcagag tcgtgtccca 250

 aatgcgaaca tcctcgtgct tacttcatgc agcttcagac ccgctctgca 300

 gatgagccga tgaccacctt ctacaagtgc tgcaatgctc agtgtggaca 350

 ccgctggagg gattagggcc aggatggccc agctgcccta gtgtgtgctt 400

 gccttgtccc tcggggtaga tgcttagctg gcagtatgag ttgtgtgtcc 450

 tgagggtctt tgctagtgtg gtggaaagat aaaccttttg aggtgaagag 500

 ccagggggtc aggaaatatg gcctatctgc caggcagggt ggatgaagtc 550

 atgaatgtct gggagttttt ctgtgtgggg aggagacaga gacccataac 600

 taaatatgct ctgtgtaaag tcctattctt tcatcttcca ctttattggc 650

 agttgacatt cccttactcc caatcaacac tcttaaatat ttgtactgtt 700

 tgtaaaactt agtacatgtc cctaaatatt taactgttac ttgtaaactt 750

 gtgtaattta ttatttattt taatcaaaat tctgaatatt tcattt 796

<210> 3300
<211> 108
<212> PRT
<213> Homo sapien

<400> 3300
 Met Leu Leu Phe Cys Pro Gly Cys Gly Asn Gly Leu Ile Val Glu
   1               5                  10                  15

 Glu Gly Gln Arg Cys His Arg Phe Ala Cys Asn Thr Cys Pro Tyr
                  20                  25                  30

 Val His Asn Ile Thr Arg Lys Val Thr Asn Arg Lys Tyr Pro Lys
                  35                  40                  45

 Leu Lys Glu Val Asp Asp Val Leu Gly Gly Ala Ala Ala Trp Glu
                  50                  55                  60

 Asn Val Asp Ser Thr Ala Glu Ser Cys Pro Lys Cys Glu His Pro
                  65                  70                  75

 Arg Ala Tyr Phe Met Gln Leu Gln Thr Arg Ser Ala Asp Glu Pro
                  80                  85                  90

 Met Thr Thr Phe Tyr Lys Cys Cys Asn Ala Gln Cys Gly His Arg
                  95                 100                 105

 Trp Arg Asp


<210> 3301
<211> 1706
<212> DNA
<213> Homo sapien

<400> 3301
 cgtttttgtt gaaagagtca ttaacggagt taggagttga tggcagtttc 50

 aataacaggt cattgccgag aaaaggatag cactataata tgcagaaatc 100

 tacaaattct gatacttccg tggaaacact gaattctacc cgccaaggca 150

 caggagctgt gcaaatgaga atcaaaaatg ccaacagcca ccatgacagg 200

 ctcagccaaa gtaaatccat gatcctcacc gatgtcggga aggtcactga 250

 acctatatcc agacacagaa ggaatcattc acagcatatc ttgaaagatg 300

 tcattcctcc attggaacaa ctgatggttg aaaaagaagg ttatctgcaa 350

 aaagctaaaa ttgcagatgg aggaaagaaa ctaaggaaaa actggtctac 400

 ttcctggatt gttctttcta gtcgaagaat tgaattttac aaagaatcca 450

 agcaacaggc tctgtccaat atgaaaactg ggcacaaacc agaaagtgtg 500

 gatttgtgtg gagcacacat tgaatgggcc aaggaaaaat cgagcagaaa 550

 gaatgtcttt cagatcacaa cagtatcagg aaatgagttc cttctacagt 600

 cagatattga cttcatcata ttggattggt tccacgctat caaaaatgca 650

 attgacagat tgccaaagga ttcaagttgt ccatcaagaa acctggaatt 700

 attcaaaatc caaagatcct ctagcactga attgctaagt cactatgaca 750

 gtgatataaa agaacagaaa ccagagcaca gaaaatcttt aatgttcaga 800

 ctgcatcaca gtgcttccga tacaagcgac aaaaatcgag ttaaaagcag 850

 attaaagaag tttattaccc gaagaccttc cctgaaaact ctgcaagaaa 900

 aaggacttat taaagatcaa atttttggct ctcatctgca caaagtgtgt 950

 gaacgtgaaa attccacagt tccgtggttt gtaaagcaat gcattgaagc 1000

 tgttgagaaa agaggtctag atgtggatgc aatatatcga gttagtggca 1050

 atctgcaaac aatacagaag ttaagattta ttgtcaacca agaagagaag 1100

 ctgaatttgg acgacagcca gtgggaggac atccacgttg tcaccggagc 1150

 actgaagatg tttttccggg agctgcctga gccgctcttc ccttacagtt 1200

 tctttgagca gtttgtggaa gcgatcaaaa agcaagacaa caacacaaga 1250

 attgaagctg taaaatctct tgtacaaaaa ctccctccgc caaatcgtga 1300

 caccatgaaa gtcctctttg gacatctaac taagatagtg gccaaagcct 1350

 ccaagaacct catgtccacg caaagcttgg ggattgtatt tggacctacc 1400

 cttctgcgag ctgaaaatga aacaggaaac atggcgatcc acatggtcta 1450

 ccagaaccag atagctgagc tcatgctgag tgagtacagt aagatcttcg 1500

 gctcagagga agactgacag acaagacaag ctactgaata cgttcacatc 1550

 tgtcttgatg cctaatattt ttacatttct gtaaacatat ttctgaaata 1600

 ttttttgcct ttcaagcgac agatgcctca ttttgtgaaa acttaatgat 1650

 gattttgtgt ttaagttcca aacatttgaa taaaataatt gacaataaaa 1700

 aaaaaa 1706

<210> 3302
<211> 475
<212> PRT
<213> Homo sapien

<400> 3302
 Met Gln Lys Ser Thr Asn Ser Asp Thr Ser Val Glu Thr Leu Asn
   1               5                  10                  15

 Ser Thr Arg Gln Gly Thr Gly Ala Val Gln Met Arg Ile Lys Asn
                  20                  25                  30

 Ala Asn Ser His His Asp Arg Leu Ser Gln Ser Lys Ser Met Ile
                  35                  40                  45

 Leu Thr Asp Val Gly Lys Val Thr Glu Pro Ile Ser Arg His Arg
                  50                  55                  60

 Arg Asn His Ser Gln His Ile Leu Lys Asp Val Ile Pro Pro Leu
                  65                  70                  75

 Glu Gln Leu Met Val Glu Lys Glu Gly Tyr Leu Gln Lys Ala Lys
                  80                  85                  90

 Ile Ala Asp Gly Gly Lys Lys Leu Arg Lys Asn Trp Ser Thr Ser
                  95                 100                 105

 Trp Ile Val Leu Ser Ser Arg Arg Ile Glu Phe Tyr Lys Glu Ser
                 110                 115                 120

 Lys Gln Gln Ala Leu Ser Asn Met Lys Thr Gly His Lys Pro Glu
                 125                 130                 135

 Ser Val Asp Leu Cys Gly Ala His Ile Glu Trp Ala Lys Glu Lys
                 140                 145                 150

 Ser Ser Arg Lys Asn Val Phe Gln Ile Thr Thr Val Ser Gly Asn
                 155                 160                 165

 Glu Phe Leu Leu Gln Ser Asp Ile Asp Phe Ile Ile Leu Asp Trp
                 170                 175                 180

 Phe His Ala Ile Lys Asn Ala Ile Asp Arg Leu Pro Lys Asp Ser
                 185                 190                 195

 Ser Cys Pro Ser Arg Asn Leu Glu Leu Phe Lys Ile Gln Arg Ser
                 200                 205                 210

 Ser Ser Thr Glu Leu Leu Ser His Tyr Asp Ser Asp Ile Lys Glu
                 215                 220                 225

 Gln Lys Pro Glu His Arg Lys Ser Leu Met Phe Arg Leu His His
                 230                 235                 240

 Ser Ala Ser Asp Thr Ser Asp Lys Asn Arg Val Lys Ser Arg Leu
                 245                 250                 255

 Lys Lys Phe Ile Thr Arg Arg Pro Ser Leu Lys Thr Leu Gln Glu
                 260                 265                 270

 Lys Gly Leu Ile Lys Asp Gln Ile Phe Gly Ser His Leu His Lys
                 275                 280                 285

 Val Cys Glu Arg Glu Asn Ser Thr Val Pro Trp Phe Val Lys Gln
                 290                 295                 300

 Cys Ile Glu Ala Val Glu Lys Arg Gly Leu Asp Val Asp Ala Ile
                 305                 310                 315

 Tyr Arg Val Ser Gly Asn Leu Gln Thr Ile Gln Lys Leu Arg Phe
                 320                 325                 330

 Ile Val Asn Gln Glu Glu Lys Leu Asn Leu Asp Asp Ser Gln Trp
                 335                 340                 345

 Glu Asp Ile His Val Val Thr Gly Ala Leu Lys Met Phe Phe Arg
                 350                 355                 360

 Glu Leu Pro Glu Pro Leu Phe Pro Tyr Ser Phe Phe Glu Gln Phe
                 365                 370                 375

 Val Glu Ala Ile Lys Lys Gln Asp Asn Asn Thr Arg Ile Glu Ala
                 380                 385                 390

 Val Lys Ser Leu Val Gln Lys Leu Pro Pro Pro Asn Arg Asp Thr
                 395                 400                 405

 Met Lys Val Leu Phe Gly His Leu Thr Lys Ile Val Ala Lys Ala
                 410                 415                 420

 Ser Lys Asn Leu Met Ser Thr Gln Ser Leu Gly Ile Val Phe Gly
                 425                 430                 435

 Pro Thr Leu Leu Arg Ala Glu Asn Glu Thr Gly Asn Met Ala Ile
                 440                 445                 450

 His Met Val Tyr Gln Asn Gln Ile Ala Glu Leu Met Leu Ser Glu
                 455                 460                 465

 Tyr Ser Lys Ile Phe Gly Ser Glu Glu Asp
                 470                 475

<210> 3303
<211> 2082
<212> DNA
<213> Homo sapien

<400> 3303
 gacaggtctg tgaagcaggc aggttgctca gctgcccccg gagcggttcc 50

 tccacctgag gcagactcca cgtcggctgg catgagccgg cgcccctgca 100

 gctgcgccct acggccaccc cgctgctcct gcagcgccag ccccagcgca 150

 gtgacagccg ccgggcgccc tcgaccctcg gatagttgta aagaagaaag 200

 ttctaccctt tctgtcaaaa tgaagtgtga ttttaattgt aaccatgttc 250

 attccggact taaactggta aaacctgatg acattggaag actagtttcc 300

 tacacccctg catatttgga aggttcctgt aaagactgca ttaaagacta 350

 tgaaaggctg tcatgtattg ggtcaccgat tgtgagccct aggattgtac 400

 aacttgaaac tgaaagcaag cgcttgcata acaaggaaaa tcaacatgtg 450

 caacagacac ttaatagtac aaatgaaata gaagcactag agaccagtag 500

 actttatgaa gacagtggct attcctcatt ttctctacaa agtggcctca 550

 gtgaacatga agaaggtagc ctcctggagg agaatttcgg tgacagtcta 600

 caatcctgcc tgctacaaat acaaagccca gaccaatatc ccaacaaaaa 650

 cttgctgcca gttcttcatt ttgaaaaagt ggtttgttca acattaaaaa 700

 agaatgcaaa acgaaatcct aaagtagatc gggagatgct gaaggaaatt 750

 atagccagag gaaattttag actgcagaat ataattggca gaaaaatggg 800

 cctagaatgt gtagatattc tcagcgaact ctttcgaagg ggactcagac 850

 atgtcttagc aactatttta gcacaactca gtgacatgga cttaatcaat 900

 gtgtctaaag tgagcacaac ttggaagaag atcctagaag atgataaggg 950

 ggcattccag ttgtacagta aagcaataca aagagttacc gaaaacaaca 1000

 ataaattttc acctcatgct tcaaccagag aatatgttat gttcagaacc 1050

 ccactggctt ctgttcagaa atcagcagcc cagacttctc tcaaaaaaga 1100

 tgctcaaacc aagttatcca atcaaggtga tcagaaaggt tctacttata 1150

 gtcgacacaa tgaattctct gaggttgcca agacattgaa aaagaacgaa 1200

 agcctcaaag cctgtattcg ctgtaattca cctgcaaaat atgattgcta 1250

 tttacaacgg gcaacctgca aacgagaagg ctgtggattt gattattgta 1300

 cgaagtgtct ctgtaattat catactacta aagactgttc agatggcaag 1350

 ctcctcaaag ccagttgtaa aataggtccc ctgcctggta caaagaaaag 1400

 caaaaagaat ttacgaagat tgtgatctct tattaaatca attgttactg 1450

 atcatgaatg ttagttagaa aatgttaggt tttaacttaa aaaaaattgt 1500

 attgtgattt tcaattttat gttgaaatcg gtgtagtatc ctgaggtttt 1550

 tttcccccca gaagataaag aggatagaca acctcttaaa atatttttac 1600

 aatttaatga gaaaaagttt aaaattctca atacaaatca aacaatttaa 1650

 atattttaag aaaaaaggaa aagtagatag tgatactgag ggtaaaaaaa 1700

 aaattgattc aattttatgg taaaggaaac ccatgcaatt ttacctagac 1750

 agtcttaaat atgtctggtt ttccatctgt tagcatttca gacattttat 1800

 gttcctctta ctcaattgat accaacagaa atatcaactt ctggagtcta 1850

 ttaaatgtgt tgtcaccttt ctaaagcttt ttttcattgt gtgtatttcc 1900

 caagaaagta tcctttgtaa aaacttgctt gttttcctta tttctgaaat 1950

 ctgttttaat atttttgtat acatgtaaat atttctgtat tttttatatg 2000

 tcaaagaata tgtctcttgt atgtacatat aaaaataaat tttgctcaat 2050

 aaaattgtaa gcttaaaaaa aaaaaaaaaa aa 2082

<210> 3304
<211> 447
<212> PRT
<213> Homo sapien

<400> 3304
 Met Ser Arg Arg Pro Cys Ser Cys Ala Leu Arg Pro Pro Arg Cys
   1               5                  10                  15

 Ser Cys Ser Ala Ser Pro Ser Ala Val Thr Ala Ala Gly Arg Pro
                  20                  25                  30

 Arg Pro Ser Asp Ser Cys Lys Glu Glu Ser Ser Thr Leu Ser Val
                  35                  40                  45

 Lys Met Lys Cys Asp Phe Asn Cys Asn His Val His Ser Gly Leu
                  50                  55                  60

 Lys Leu Val Lys Pro Asp Asp Ile Gly Arg Leu Val Ser Tyr Thr
                  65                  70                  75

 Pro Ala Tyr Leu Glu Gly Ser Cys Lys Asp Cys Ile Lys Asp Tyr
                  80                  85                  90

 Glu Arg Leu Ser Cys Ile Gly Ser Pro Ile Val Ser Pro Arg Ile
                  95                 100                 105

 Val Gln Leu Glu Thr Glu Ser Lys Arg Leu His Asn Lys Glu Asn
                 110                 115                 120

 Gln His Val Gln Gln Thr Leu Asn Ser Thr Asn Glu Ile Glu Ala
                 125                 130                 135

 Leu Glu Thr Ser Arg Leu Tyr Glu Asp Ser Gly Tyr Ser Ser Phe
                 140                 145                 150

 Ser Leu Gln Ser Gly Leu Ser Glu His Glu Glu Gly Ser Leu Leu
                 155                 160                 165

 Glu Glu Asn Phe Gly Asp Ser Leu Gln Ser Cys Leu Leu Gln Ile
                 170                 175                 180

 Gln Ser Pro Asp Gln Tyr Pro Asn Lys Asn Leu Leu Pro Val Leu
                 185                 190                 195

 His Phe Glu Lys Val Val Cys Ser Thr Leu Lys Lys Asn Ala Lys
                 200                 205                 210

 Arg Asn Pro Lys Val Asp Arg Glu Met Leu Lys Glu Ile Ile Ala
                 215                 220                 225

 Arg Gly Asn Phe Arg Leu Gln Asn Ile Ile Gly Arg Lys Met Gly
                 230                 235                 240

 Leu Glu Cys Val Asp Ile Leu Ser Glu Leu Phe Arg Arg Gly Leu
                 245                 250                 255

 Arg His Val Leu Ala Thr Ile Leu Ala Gln Leu Ser Asp Met Asp
                 260                 265                 270

 Leu Ile Asn Val Ser Lys Val Ser Thr Thr Trp Lys Lys Ile Leu
                 275                 280                 285

 Glu Asp Asp Lys Gly Ala Phe Gln Leu Tyr Ser Lys Ala Ile Gln
                 290                 295                 300

 Arg Val Thr Glu Asn Asn Asn Lys Phe Ser Pro His Ala Ser Thr
                 305                 310                 315

 Arg Glu Tyr Val Met Phe Arg Thr Pro Leu Ala Ser Val Gln Lys
                 320                 325                 330

 Ser Ala Ala Gln Thr Ser Leu Lys Lys Asp Ala Gln Thr Lys Leu
                 335                 340                 345

 Ser Asn Gln Gly Asp Gln Lys Gly Ser Thr Tyr Ser Arg His Asn
                 350                 355                 360

 Glu Phe Ser Glu Val Ala Lys Thr Leu Lys Lys Asn Glu Ser Leu
                 365                 370                 375

 Lys Ala Cys Ile Arg Cys Asn Ser Pro Ala Lys Tyr Asp Cys Tyr
                 380                 385                 390

 Leu Gln Arg Ala Thr Cys Lys Arg Glu Gly Cys Gly Phe Asp Tyr
                 395                 400                 405

 Cys Thr Lys Cys Leu Cys Asn Tyr His Thr Thr Lys Asp Cys Ser
                 410                 415                 420

 Asp Gly Lys Leu Leu Lys Ala Ser Cys Lys Ile Gly Pro Leu Pro
                 425                 430                 435

 Gly Thr Lys Lys Ser Lys Lys Asn Leu Arg Arg Leu
                 440                 445

<210> 3305
<211> 1780
<212> DNA
<213> Homo sapien

<400> 3305
 ggcgctcgca gagccggaaa gaagtgctgt aagggacgct cgggggacgc 50

 tgttcctgag gtgtcgccgc ctccctgtcc tcgccctccg cggtggggga 100

 gaaacccagg agcgaagccc agagcccgcg gcgcggccgg cggacgaacg 150

 agcgcgcagc agccggtgcg cggccgcggc gagggcgggg gaagaaaaac 200

 accctgtttc ctctccggcc cccaccgcgg atcatgtacc aggattatcc 250

 cgggaacttt gacacctcgt cccggggcag cagcggctct cctgcgcacg 300

 ccgagtccta ctccagcggc ggcggcggcc agcagaaatt ccgggtagat 350

 atgcctggct caggcagtgc attcatcccc accatcaacg ccatcacgac 400

 cagccaggac ctgcagtgga tggtgcagcc cacagtgatc acctccatgt 450

 ccaacccata ccctcgctcg cacccctaca gccccctgcc gggcctggcc 500

 tctgtccctg gacacatggc cctcccaaga cctggcgtga tcaagaccat 550

 tggcaccacc gtgggccgca ggaggagaga tgagcagctg tctcctgaag 600

 aggaggagaa gcgtcgcatc cggcgggaga ggaacaagct ggctgcagcc 650

 aagtgccgga accgacgccg ggagctgaca gagaagctgc aggcggagac 700

 agaggagctg gaggaggaga agtcaggcct gcagaaggag attgctgagc 750

 tgcagaagga gaaggagaag ctggagttca tgttggtggc tcacggccca 800

 gtgtgcaaga ttagccccga ggagcgccga tcgcccccag cccctgggct 850

 gcagcccatg cgcagtgggg gtggctcggt gggcgctgta gtggtgaaac 900

 aggagcccct ggaagaggac agcccctcgt cctcgtcggc ggggctggac 950

 aaggcccagc gctctgtcat caagcccatc agcattgctg ggggcttcta 1000

 cggtgaggag cccctgcaca cccccatcgt ggtgacctcc acacctgctg 1050

 tcactccggg cacctcgaac ctcgtcttca cctatcctag cgtcctggag 1100

 caggagtcac ccgcatctcc ctccgaatcc tgctccaagg ctcaccgcag 1150

 aagcagtagc agcggggacc aatcatcaga ctccttgaac tcccccactc 1200

 tgctggctct gtaacccagt gcacctccct ccccagctcc ggagggggtc 1250

 ctcctcgctc ctccttccca gggaccagca ccttcaagcg ctccagggcc 1300

 gtgagggcaa gagggggacc tgccaccagg gagcttcctg gctctggggg 1350

 acccaggtgg gacttagcag tgagtattgg aagacttggg ttgatctctt 1400

 agaagccatg ggacctcctc cctcattcat cttgcaagca aatcccattt 1450

 cttgaaaagc cttggagaac tcggtttggt agacttggac atctctctgg 1500

 cttctgaaga gcctgaagct ggcctggacc attcctgtcc ctttgttacc 1550

 atactgtctc tggagtgatg gtgtccttcc ctgccccacc acgcatgctc 1600

 agtgcctttt ggtttcacct tccctcgact tgaccctttc ctcccccagc 1650

 gtcagtttca ctccctcttg gtttttatca aatttgccat gacatttcat 1700

 ctgggtggtc tgaatattaa agctcttcat ttctggaaaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1780

<210> 3306
<211> 326
<212> PRT
<213> Homo sapien

<400> 3306
 Met Tyr Gln Asp Tyr Pro Gly Asn Phe Asp Thr Ser Ser Arg Gly
   1               5                  10                  15

 Ser Ser Gly Ser Pro Ala His Ala Glu Ser Tyr Ser Ser Gly Gly
                  20                  25                  30

 Gly Gly Gln Gln Lys Phe Arg Val Asp Met Pro Gly Ser Gly Ser
                  35                  40                  45

 Ala Phe Ile Pro Thr Ile Asn Ala Ile Thr Thr Ser Gln Asp Leu
                  50                  55                  60

 Gln Trp Met Val Gln Pro Thr Val Ile Thr Ser Met Ser Asn Pro
                  65                  70                  75

 Tyr Pro Arg Ser His Pro Tyr Ser Pro Leu Pro Gly Leu Ala Ser
                  80                  85                  90

 Val Pro Gly His Met Ala Leu Pro Arg Pro Gly Val Ile Lys Thr
                  95                 100                 105

 Ile Gly Thr Thr Val Gly Arg Arg Arg Arg Asp Glu Gln Leu Ser
                 110                 115                 120

 Pro Glu Glu Glu Glu Lys Arg Arg Ile Arg Arg Glu Arg Asn Lys
                 125                 130                 135

 Leu Ala Ala Ala Lys Cys Arg Asn Arg Arg Arg Glu Leu Thr Glu
                 140                 145                 150

 Lys Leu Gln Ala Glu Thr Glu Glu Leu Glu Glu Glu Lys Ser Gly
                 155                 160                 165

 Leu Gln Lys Glu Ile Ala Glu Leu Gln Lys Glu Lys Glu Lys Leu
                 170                 175                 180

 Glu Phe Met Leu Val Ala His Gly Pro Val Cys Lys Ile Ser Pro
                 185                 190                 195

 Glu Glu Arg Arg Ser Pro Pro Ala Pro Gly Leu Gln Pro Met Arg
                 200                 205                 210

 Ser Gly Gly Gly Ser Val Gly Ala Val Val Val Lys Gln Glu Pro
                 215                 220                 225

 Leu Glu Glu Asp Ser Pro Ser Ser Ser Ser Ala Gly Leu Asp Lys
                 230                 235                 240

 Ala Gln Arg Ser Val Ile Lys Pro Ile Ser Ile Ala Gly Gly Phe
                 245                 250                 255

 Tyr Gly Glu Glu Pro Leu His Thr Pro Ile Val Val Thr Ser Thr
                 260                 265                 270

 Pro Ala Val Thr Pro Gly Thr Ser Asn Leu Val Phe Thr Tyr Pro
                 275                 280                 285

 Ser Val Leu Glu Gln Glu Ser Pro Ala Ser Pro Ser Glu Ser Cys
                 290                 295                 300

 Ser Lys Ala His Arg Arg Ser Ser Ser Ser Gly Asp Gln Ser Ser
                 305                 310                 315

 Asp Ser Leu Asn Ser Pro Thr Leu Leu Ala Leu
                 320                 325

<210> 3307
<211> 1820
<212> DNA
<213> Homo sapien

<400> 3307
 tgacatttca tctgggtggt ctgaatatta aagctcttca tttctggaga 50

 tggggcagca ggtggctctt ctgctggggc tgacttgtcc agaaggggac 100

 aaagtgcaat acagagcctt ccctaccctg acgcctccca gtcatcatct 150

 ccagaactcc cagcggggct ccctgagctc tcaaggagat gctgccatca 200

 ctgggaggct cagaggaccc ttcctgccca ccttcggaga cggcttctgg 250

 aggaacggct tggccagaag acagggtgtg agtgagacag tggggcacag 300

 gttgggtttg ccaaacgcct aattaccagg ccaggaagca tgccaacaaa 350

 gccacacggg tgtcctagcc agcttccctt cacctggtgt cttgagtagg 400

 gcgtctcctg taattactgc cttgccattc tgcccctgga cccttctctc 450

 cggaccaggg aggcgtccct ccctatgagc cacacattat actccaagtc 500

 cctgccgggc tccgcctttc ccccaccctg gctctcaggg tgacgccacc 550

 cacagagatt taatgagcgt gggcctggac cttccccaga tgctgccagg 600

 cagcccctcc ccaagcctca aagaagcatt tgctgaggat ggagaggcag 650

 gggagggagg cgggaggccg tcactggagt ggcgtctgca gcagctgctg 700

 ccccagcacc cgctcagcct gtcctggctg ctcacctccc cgcagggcac 750

 cgggcctttc ctgccctctg tggtcatctg ccacctgctg gatcaagtgc 800

 tttctctttt acactcccct gtccccaccc cagtgcactc ttctggccca 850

 ggcagcaagc aagctgtgaa cagctggcct gagctgtcgc tgtggcttgt 900

 ggctcatgcg ccattcctgg ttgtctgttg aatctttctg gctgctggaa 950

 ttggagatag gatgttttgc ttcccactgc aggagagctg ccccctttca 1000

 cggggttggg gaagggtccc cctggcctcc agcaggagca cagctcagca 1050

 gggtccctgc tgcccacccc tctgagcctt ttctccccag ggtatggctc 1100

 ctgctgagtt tcttgtccag cagggccttg acaggaatcc agggagtagc 1150

 tcctggccag aaccagcctc tgcggggctt gtgctctgca aagactctgc 1200

 tgctggggat tcagctctag aggtcacagt atcctcgttt gaaagataat 1250

 taagatcccc cgtggagaaa gcagtgacac attcacacag ctgttccctc 1300

 gcatgttatt tcatgaacat gacctgtttt cgtgcactag acacacagag 1350

 tggaacagcc gtatgcttaa agtacatggg ccagtgggac tggaagtgac 1400

 ctgtacaagt gatgcagaaa ggagggtttc aaagaaaaag gattttgttt 1450

 aaaatacttt aaaaatgtta tttcctgcat cccttggctg tgatgcccct 1500

 ctcccgattt cccaggggct ctgggaggga cccttctaag aagattgggc 1550

 agttgggttt ctggcttgag atgaatccaa gcagcagaat gagccaggag 1600

 tagcaggaga tgggcaaaga aaactggggt gcactcagct ctcacagggg 1650

 taatcatctc aagtggtatt tgtagccaag tgggagctat tttctttttt 1700

 gtgcatatag atatttctta aatgaaaaaa aaaaaaaaaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaaaaaaaaa aaaaaaaaaa 1820

<210> 3308
<211> 122
<212> PRT
<213> Homo sapien

<400> 3308
 Met Ser Val Gly Leu Asp Leu Pro Gln Met Leu Pro Gly Ser Pro
   1               5                  10                  15

 Ser Pro Ser Leu Lys Glu Ala Phe Ala Glu Asp Gly Glu Ala Gly
                  20                  25                  30

 Glu Gly Gly Gly Arg Pro Ser Leu Glu Trp Arg Leu Gln Gln Leu
                  35                  40                  45

 Leu Pro Gln His Pro Leu Ser Leu Ser Trp Leu Leu Thr Ser Pro
                  50                  55                  60

 Gln Gly Thr Gly Pro Phe Leu Pro Ser Val Val Ile Cys His Leu
                  65                  70                  75

 Leu Asp Gln Val Leu Ser Leu Leu His Ser Pro Val Pro Thr Pro
                  80                  85                  90

 Val His Ser Ser Gly Pro Gly Ser Lys Gln Ala Val Asn Ser Trp
                  95                 100                 105

 Pro Glu Leu Ser Leu Trp Leu Val Ala His Ala Pro Phe Leu Val
                 110                 115                 120

 Val Cys


<210> 3309
<211> 1554
<212> DNA
<213> Homo sapien

<400> 3309
 aattatatat ttttactcta tgtttctcta catgtttttt tctttccgtt 50

 gctggcggaa gaggcacgtg cgctgctgaa tggagctggt cgctggttgc 100

 tacgagcagg tcctctttgg gttcgctgta cacccggagc ccaaggcttg 150

 cggcgaccac gagcaatgga ctcttgtggc tgacttcact caccatgctc 200

 acactgcctc cttgtcagca gtagctgtaa atagtcgttt tgtggtcact 250

 gggagcaaag atgaaacaat tcacatttat gacatgaaaa agaagattga 300

 gcatggggct ctagtgcatc acagtggtac aataacttgc ctgaaattct 350

 atggcaacag gcatttaatc agtggagcgg aagatggact catctgtatc 400

 tgggatgcaa agaaatggga atgcctgaag tcaattaaag ctcacaaagg 450

 acaggtgacc ttcctttcta ttcacccatc tggcaagttg gccctgtcgg 500

 ttggtacaga taaaacttta agaacgtgga atcttgtaga aggaagatca 550

 gcattcataa aaaatataaa acaaaatgct cacatagtag aatggtcccc 600

 aagaggagag cagtatgtag ttatcataca gaataaaata gacatctatc 650

 agcttgacac tgcatccatt agtggcacca tcacaaatga aaagagaatt 700

 tcctctgtta aatttctttc agagtctgtc cttgcagtgg ctggagatga 750

 agaagttata aggttttttg actgtgattc actagtgtgc ctctgcgaat 800

 ttaaagctca tgaaaacagg gtaaaggaca tgttcagttt tgaaattcca 850

 gagcatcatg ttattgtttc agcatcgagt gatggtttca tcaaaatgtg 900

 gaagcttaag caggataaga aagttccccc atctttactc tgtgaaataa 950

 acactaatgc caggctgacg tgtcttggag tgtggctaga caaagtggca 1000

 gacatgaaaa gccttcctcc agctgcagag ccttctcctg taagtaaaga 1050

 acagtccaaa attggcaaaa aggagcctgg tgacacagtg cacaaagaag 1100

 aaaagcggtc aaaacctaac acaaagaaac gcggtttaac aggtgacagt 1150

 aagaaagcaa caaaagaaag tggcctgata tcaaccaaga agaggaaaat 1200

 ggtagaaatg ttggaaaaga agaggaaaaa gaagaaaata aaaacaatgc 1250

 agtgaatcac agatgtctcc tgaaagaact cttttagatg aaatcattct 1300

 actcaaatgt accttaattt ttttttttcc ctgagtaaaa gcaagaaatt 1350

 tcttcctttg gaaaaaatat atatattaaa aaaccacttt tagatggttt 1400

 tttttaaaaa aaaaaaaaaa actggtaaaa ttacttttgg cagacagtgt 1450

 tttatgaatt atgtatcatg ttgatatata atatgttaat gtgtcatgta 1500

 atttttactt tgtacaaagc aaataaagat ctttctcaaa aaaaaaaaaa 1550

 aaaa 1554

<210> 3310
<211> 391
<212> PRT
<213> Homo sapien

<400> 3310
 Met Glu Leu Val Ala Gly Cys Tyr Glu Gln Val Leu Phe Gly Phe
   1               5                  10                  15

 Ala Val His Pro Glu Pro Lys Ala Cys Gly Asp His Glu Gln Trp
                  20                  25                  30

 Thr Leu Val Ala Asp Phe Thr His His Ala His Thr Ala Ser Leu
                  35                  40                  45

 Ser Ala Val Ala Val Asn Ser Arg Phe Val Val Thr Gly Ser Lys
                  50                  55                  60

 Asp Glu Thr Ile His Ile Tyr Asp Met Lys Lys Lys Ile Glu His
                  65                  70                  75

 Gly Ala Leu Val His His Ser Gly Thr Ile Thr Cys Leu Lys Phe
                  80                  85                  90

 Tyr Gly Asn Arg His Leu Ile Ser Gly Ala Glu Asp Gly Leu Ile
                  95                 100                 105

 Cys Ile Trp Asp Ala Lys Lys Trp Glu Cys Leu Lys Ser Ile Lys
                 110                 115                 120

 Ala His Lys Gly Gln Val Thr Phe Leu Ser Ile His Pro Ser Gly
                 125                 130                 135

 Lys Leu Ala Leu Ser Val Gly Thr Asp Lys Thr Leu Arg Thr Trp
                 140                 145                 150

 Asn Leu Val Glu Gly Arg Ser Ala Phe Ile Lys Asn Ile Lys Gln
                 155                 160                 165

 Asn Ala His Ile Val Glu Trp Ser Pro Arg Gly Glu Gln Tyr Val
                 170                 175                 180

 Val Ile Ile Gln Asn Lys Ile Asp Ile Tyr Gln Leu Asp Thr Ala
                 185                 190                 195

 Ser Ile Ser Gly Thr Ile Thr Asn Glu Lys Arg Ile Ser Ser Val
                 200                 205                 210

 Lys Phe Leu Ser Glu Ser Val Leu Ala Val Ala Gly Asp Glu Glu
                 215                 220                 225

 Val Ile Arg Phe Phe Asp Cys Asp Ser Leu Val Cys Leu Cys Glu
                 230                 235                 240

 Phe Lys Ala His Glu Asn Arg Val Lys Asp Met Phe Ser Phe Glu
                 245                 250                 255

 Ile Pro Glu His His Val Ile Val Ser Ala Ser Ser Asp Gly Phe
                 260                 265                 270

 Ile Lys Met Trp Lys Leu Lys Gln Asp Lys Lys Val Pro Pro Ser
                 275                 280                 285

 Leu Leu Cys Glu Ile Asn Thr Asn Ala Arg Leu Thr Cys Leu Gly
                 290                 295                 300

 Val Trp Leu Asp Lys Val Ala Asp Met Lys Ser Leu Pro Pro Ala
                 305                 310                 315

 Ala Glu Pro Ser Pro Val Ser Lys Glu Gln Ser Lys Ile Gly Lys
                 320                 325                 330

 Lys Glu Pro Gly Asp Thr Val His Lys Glu Glu Lys Arg Ser Lys
                 335                 340                 345

 Pro Asn Thr Lys Lys Arg Gly Leu Thr Gly Asp Ser Lys Lys Ala
                 350                 355                 360

 Thr Lys Glu Ser Gly Leu Ile Ser Thr Lys Lys Arg Lys Met Val
                 365                 370                 375

 Glu Met Leu Glu Lys Lys Arg Lys Lys Lys Lys Ile Lys Thr Met
                 380                 385                 390

 Gln


<210> 3311
<211> 3653
<212> DNA
<213> Homo sapien

<400> 3311
 acgcggcgct cgcgctccct ccttaaatga gcctgggcgc cccgcgcccg 50

 ccacttcagt ggatcccgcg ccggggccgc gggcggagct gcctgccggt 100

 cccgcgccgc gcgtccgcac tcctcggccc tcgggcggtc gatgggacgg 150

 ggcgccgcgg agcaggaggc ggcgcccgtc ggggtgctcg ggccgcgcgg 200

 gagcccactg tggggctcgg gcatggcggg ccgcaggacc tgagctctcc 250

 tcaggggagc ggggaggcag ctgctggccg gcgatgggga cggagtgggg 300

 ccgtcgccgc cgcgccgagc cgtgagcgcc gagccaccgc cgccgctacc 350

 tcagcccttc gcgaagcgcc gggcagctcg ggaacatggc cctggagcgg 400

 ctctgctcgg tcctcaaagt gttgttaata acagtactgg tagtggaagg 450

 gattgccgtg gcccaaaaaa cccaagatgg acaaaatatt ggaatcaagc 500

 atattcctgc aacccagtgt ggcatttggg ttcgaaccag caatggaggt 550

 cattttgctt cgccaaatta tcctgactca tatccaccaa acaaggagtg 600

 tatctacatt ttggaagctg ctccacgtca aagaatagag ttgacctttg 650

 atgaacatta ttatatagaa ccatcatttg agtgtcggtt tgatcacttg 700

 gaagttcgag atgggccatt tggtttctct cctcttatag atcgttactg 750

 tggcgtgaaa agccctccat taattagatc aacagggaga ttcatgtgga 800

 ttaagtttag ttctgatgaa gagcttgaag gactgggatt tcgagcaaaa 850

 tattcattta ttccagatcc agactttact tacctaggag gtattttaaa 900

 tcccattcca gattgtcagt tcgagctctc gggagctgat ggaatagtgc 950

 gctctagtca ggtagaacaa gaggagaaaa caaaaccagg ccaagccgtt 1000

 gattgcatct ggaccattaa agccactcca aaagctaaga tttatttgag 1050

 gttcctagat tatcaaatgg agcactcaaa tgaatgcaag agaaacttcg 1100

 ttgcagtcta tgatggaagc agttctattg aaaacctgaa ggccaagttt 1150

 tgcagcactg tggccaatga tgtaatgctt aaaacaggaa ttggagtgat 1200

 tcgaatgtgg gcagatgaag gtagtcggct tagcaggttt cgaatgctct 1250

 ttacttcctt tgtggagcct ccctgcacaa gcagcacttt cttttgccat 1300

 agcaacatgt gcatcaataa ttctttagtc tgtaatggtg tccaaaattg 1350

 tgcataccct tgggatgaaa atcattgtaa agaaaagaaa aaagcaggag 1400

 tatttgaaca aatcactaag actcatggaa caattattgg cattacttca 1450

 gggattgtct tggtccttct cattatttct attttagtac aagtgaaaca 1500

 gcctcgaaaa aaggtcatgg cttgcaaaac cgcttttaat aaaaccgggt 1550

 tccaagaagt gtttgatcct cctcattatg aactgttttc actaagggac 1600

 aaagagattt ctgcagacct ggcagacttg tcggaagaat tggacaacta 1650

 ccagaagatg cggcgctcct ccaccgcctc ccgctgcatc cacgaccacc 1700

 actgtgggtc gcaggcctcc agcgtcaaac aaagcaggac caacctcagt 1750

 tccatggaac ttcctttccg aaatgacttt gcacaaccac agccaatgaa 1800

 aacatttaat agcaccttca agaaaagtag ttacactttc aaacagggac 1850

 atgagtgccc tgagcaggcc ctggaagacc gagtaatgga ggagattccc 1900

 tgtgaaattt atgtcagggg gcgagaagat tctgcacaag catccatatc 1950

 cattgacttc taatcttctg ctaatggtga tgtgaattct tagggtgtgt 2000

 acgtacgcag cctccagggc accatactgt ttccagcagc caaccctttt 2050

 ctcccatcac aactacgaag accttgattt accgttaacc tattgtatgg 2100

 tgatgttttt attctctcag gcagtctata tatgttaaac caatcaagga 2150

 acttactcta ttcagtggaa acaataatca tctctattgc ttggtgtcat 2200

 ttataggaag cactgccagt taaagagcat tagaagaggt ggttggatgg 2250

 agccaggctc aggctgcctc ttcgttttag caacaagaag actgctcttg 2300

 actgataaca gctctgtcaa tattttgatg ccacaataaa cttgattttt 2350

 ctttacattc cttttatttt tcctttctct aaatttaatt tgttttataa 2400

 gcctatcgtt ttaccatttc attttcttac ataagtacaa gtggttaatg 2450

 taccacatac ttcagtatag gcatttgttc ttgagtgtgt caaaatacag 2500

 ctagttactg tgccaattaa gacccagttg tatttcaccc atctgtttct 2550

 tcttggctaa tctctgtact tctgcctttt aattactggg cccttattcc 2600

 ttattttctg tgagaaataa tagatgatat gatttattac ctttcaatta 2650

 tatttttctc agttatacta gaaaatttca taatcctggg atatatgtac 2700

 cattgtcagc tatgactaaa aatttgaaaa agataaaaat ttctagcaag 2750

 cctttgaagt ttaccaagta tagtcacatt cagtgacagc ccattcattc 2800

 cagtaaagaa tcatttcatt cactttggga gaggcctata attacattta 2850

 tttgcaatgt ttctcttcgc tagattgtta catagctccc attctgttgg 2900

 ttttgcttac agcatatggt aaccaaggtt agatgccagt taaaattcct 2950

 tagaaattgg atgagccttg agattgcttc ttaactggga catgacattt 3000

 ttctagctct tatcaagaat aacaacttcc actttttttt aaactgcact 3050

 tttgactttt tttatggtat aaaaacaata atttataaac ataaaagctc 3100

 attgtgtttt ttagactttt gatattattt gatactgtac aaactttatt 3150

 aaatcaagat gaaagaccta caggacagat tcctttcagt gttcacatca 3200

 gtggctttgt atgcaaatat gctgtgttgg acctggacgc tataacttat 3250

 tgtaaagacc ttggaaatgt ggacataagc tctttctttc cttttgttac 3300

 tgtatttagt ttgtgataaa tttttcactg tgtgatattt atgctctaaa 3350

 tcactacaca aatcccatat taaaatatac attgtacctg accctttaat 3400

 catgttattt atgccaccaa ggttgtggat cttaaggtat gtatggaaag 3450

 gaactcattt atcaaattgt aagtaataca gacatgccat ttaaaagagg 3500

 taaattcttg ttttctatat tttgttagta aattctcaat gaaataagtt 3550

 gaagtttcac tggatttcat taacttttaa atattacata tatgtgtttt 3600

 ctcagattag tgaaaattgt gaccttaaat ttaatacaca tatactgcct 3650

 cag 3653

<210> 3312
<211> 525
<212> PRT
<213> Homo sapien

<400> 3312
 Met Ala Leu Glu Arg Leu Cys Ser Val Leu Lys Val Leu Leu Ile
   1               5                  10                  15

 Thr Val Leu Val Val Glu Gly Ile Ala Val Ala Gln Lys Thr Gln
                  20                  25                  30

 Asp Gly Gln Asn Ile Gly Ile Lys His Ile Pro Ala Thr Gln Cys
                  35                  40                  45

 Gly Ile Trp Val Arg Thr Ser Asn Gly Gly His Phe Ala Ser Pro
                  50                  55                  60

 Asn Tyr Pro Asp Ser Tyr Pro Pro Asn Lys Glu Cys Ile Tyr Ile
                  65                  70                  75

 Leu Glu Ala Ala Pro Arg Gln Arg Ile Glu Leu Thr Phe Asp Glu
                  80                  85                  90

 His Tyr Tyr Ile Glu Pro Ser Phe Glu Cys Arg Phe Asp His Leu
                  95                 100                 105

 Glu Val Arg Asp Gly Pro Phe Gly Phe Ser Pro Leu Ile Asp Arg
                 110                 115                 120

 Tyr Cys Gly Val Lys Ser Pro Pro Leu Ile Arg Ser Thr Gly Arg
                 125                 130                 135

 Phe Met Trp Ile Lys Phe Ser Ser Asp Glu Glu Leu Glu Gly Leu
                 140                 145                 150

 Gly Phe Arg Ala Lys Tyr Ser Phe Ile Pro Asp Pro Asp Phe Thr
                 155                 160                 165

 Tyr Leu Gly Gly Ile Leu Asn Pro Ile Pro Asp Cys Gln Phe Glu
                 170                 175                 180

 Leu Ser Gly Ala Asp Gly Ile Val Arg Ser Ser Gln Val Glu Gln
                 185                 190                 195

 Glu Glu Lys Thr Lys Pro Gly Gln Ala Val Asp Cys Ile Trp Thr
                 200                 205                 210

 Ile Lys Ala Thr Pro Lys Ala Lys Ile Tyr Leu Arg Phe Leu Asp
                 215                 220                 225

 Tyr Gln Met Glu His Ser Asn Glu Cys Lys Arg Asn Phe Val Ala
                 230                 235                 240

 Val Tyr Asp Gly Ser Ser Ser Ile Glu Asn Leu Lys Ala Lys Phe
                 245                 250                 255

 Cys Ser Thr Val Ala Asn Asp Val Met Leu Lys Thr Gly Ile Gly
                 260                 265                 270

 Val Ile Arg Met Trp Ala Asp Glu Gly Ser Arg Leu Ser Arg Phe
                 275                 280                 285

 Arg Met Leu Phe Thr Ser Phe Val Glu Pro Pro Cys Thr Ser Ser
                 290                 295                 300

 Thr Phe Phe Cys His Ser Asn Met Cys Ile Asn Asn Ser Leu Val
                 305                 310                 315

 Cys Asn Gly Val Gln Asn Cys Ala Tyr Pro Trp Asp Glu Asn His
                 320                 325                 330

 Cys Lys Glu Lys Lys Lys Ala Gly Val Phe Glu Gln Ile Thr Lys
                 335                 340                 345

 Thr His Gly Thr Ile Ile Gly Ile Thr Ser Gly Ile Val Leu Val
                 350                 355                 360

 Leu Leu Ile Ile Ser Ile Leu Val Gln Val Lys Gln Pro Arg Lys
                 365                 370                 375

 Lys Val Met Ala Cys Lys Thr Ala Phe Asn Lys Thr Gly Phe Gln
                 380                 385                 390

 Glu Val Phe Asp Pro Pro His Tyr Glu Leu Phe Ser Leu Arg Asp
                 395                 400                 405

 Lys Glu Ile Ser Ala Asp Leu Ala Asp Leu Ser Glu Glu Leu Asp
                 410                 415                 420

 Asn Tyr Gln Lys Met Arg Arg Ser Ser Thr Ala Ser Arg Cys Ile
                 425                 430                 435

 His Asp His His Cys Gly Ser Gln Ala Ser Ser Val Lys Gln Ser
                 440                 445                 450

 Arg Thr Asn Leu Ser Ser Met Glu Leu Pro Phe Arg Asn Asp Phe
                 455                 460                 465

 Ala Gln Pro Gln Pro Met Lys Thr Phe Asn Ser Thr Phe Lys Lys
                 470                 475                 480

 Ser Ser Tyr Thr Phe Lys Gln Gly His Glu Cys Pro Glu Gln Ala
                 485                 490                 495

 Leu Glu Asp Arg Val Met Glu Glu Ile Pro Cys Glu Ile Tyr Val
                 500                 505                 510

 Arg Gly Arg Glu Asp Ser Ala Gln Ala Ser Ile Ser Ile Asp Phe
                 515                 520                 525

<210> 3313
<211> 2111
<212> DNA
<213> Homo sapien

<400> 3313
 ccagagatgt taaaaacatt tttatgccta agaatcaagg aagtagaagt 50

 gaaaaaagat acagaagaca ttaataaacc aaaaaaattt atgactttca 100

 aagaaaagag aaaatctcta tcaagaatgc agagaaagtg gaagaaagca 150

 gaagagaaac tagagcgaga gcttcgagag gcagaagctt cagagagtac 200

 tgagaaaaaa cttaaactgc acacagagac tctgaatatt gtgtttgtaa 250

 cctacttcag aatattgaag aaggcccaga ggtcacctct cctgccagca 300

 gttctagaag gtcttgccaa gtttgctcac cttataaatg tggaattttt 350

 tgatgatctg ttagtagttc ttcatactct cattgagtct ggtgacctaa 400

 gctatcaaga aagtcttcac tgtgtccaga ctgcttttca tattctttct 450

 ggacaaggtg atgttctgaa tattgatcca ttgaaattct acacacatct 500

 ctacaaaaca ctgttcaaat tacatgcagg tgctaccaat gaaggtgttg 550

 agattgtact ccagtgcctt gatgtcatgc taactaagcg cagaaagcaa 600

 gtttctcagc agcgagctct tgccttcatc aaacgccttt gtacccttgc 650

 tcttcatgtt cttccaaatt caagtattgg cattttagca actaccagaa 700

 tattaatgca tactttcccc aaaacagatc tactgcttga cagtgaatct 750

 cagggaagtg gagttttcct tcctgaactg gatgagcctg agtactgcaa 800

 tgctcagaac actgctctgt gggaactgca tgctctgcgg aggcattatc 850

 atcccatagt gcagagattt gcagcccacc tgatcgctgg agcaccttct 900

 gaaggctctg gagcactcaa accagagttg agtcgaagat ctgctactga 950

 actttttgag gcatatagca tggcagaaat gacattcaat cctcctgttg 1000

 aatcttcaaa ccccaaaata aagggtaaat ttttacaagg ggattcattt 1050

 ttgaatgaag atttaaatca gctaatcaaa agatactcca gtgaagttgc 1100

 tactgaatcg cctctggatt tcacgaaata tttgaaaaca tcactacact 1150

 agtagaggaa tgaagtcagt ggactttctt gtatatttgt gtgtgcagat 1200

 gtacataaag atgagttgtt aacttaggat cttttctttt tatacaagga 1250

 aagcttccta agaatgtcta ggaagaagag gaagaatgac cctttgcatg 1300

 gcacagggtt ctgcccctat tctgaatatg tcattccatc aaggagatca 1350

 aaagcctttt tttctcccca gtatttggaa attactttct tgatgatgct 1400

 gccttttaaa agcttcacgt acattatagt tttttaaaaa aatctttgga 1450

 ctggatctta ctgaagtgca gttgctatat taaaattagg gcatagagca 1500

 cagaaaaatc aagaccatga gaagacattt taccatttag ctacttttta 1550

 taactaaata ctctttaaat atttttattt caatactgtg gatggaaatg 1600

 agaagcattc taaatttgag ttaatatatt tttatgaaga tatttgagaa 1650

 aagaaaaaaa tagcttgtat tcaggttcat tggcttttgc tggatgatcc 1700

 acctaaagaa gttacctaat ttggcctttt aaaaaaggtg ttagtgttta 1750

 ttatagctac tttcaaggaa agtttgaata tgattctagt ctctaaagtt 1800

 cttcacgttt tctgacattc cctggagggt gactggggaa gaattgctcc 1850

 agggtagaag aaccaggccc aagactttac cattctgatc tagagacaaa 1900

 ggatactcaa tgaggagctt ttttcccctc ttggaacagg taaaatgctt 1950

 tttcttatta atataattat aaaacagtat tttatgtaac agctattccc 2000

 atattctagg agtggcctaa gaaatgcgtg tttcagtgac tagattataa 2050

 atattctcta ttgtgaatag ttgaataaaa cagctgtttt tttctgcaaa 2100

 aaaaaaaaaa a 2111

<210> 3314
<211> 381
<212> PRT
<213> Homo sapien

<400> 3314
 Met Leu Lys Thr Phe Leu Cys Leu Arg Ile Lys Glu Val Glu Val
   1               5                  10                  15

 Lys Lys Asp Thr Glu Asp Ile Asn Lys Pro Lys Lys Phe Met Thr
                  20                  25                  30

 Phe Lys Glu Lys Arg Lys Ser Leu Ser Arg Met Gln Arg Lys Trp
                  35                  40                  45

 Lys Lys Ala Glu Glu Lys Leu Glu Arg Glu Leu Arg Glu Ala Glu
                  50                  55                  60

 Ala Ser Glu Ser Thr Glu Lys Lys Leu Lys Leu His Thr Glu Thr
                  65                  70                  75

 Leu Asn Ile Val Phe Val Thr Tyr Phe Arg Ile Leu Lys Lys Ala
                  80                  85                  90

 Gln Arg Ser Pro Leu Leu Pro Ala Val Leu Glu Gly Leu Ala Lys
                  95                 100                 105

 Phe Ala His Leu Ile Asn Val Glu Phe Phe Asp Asp Leu Leu Val
                 110                 115                 120

 Val Leu His Thr Leu Ile Glu Ser Gly Asp Leu Ser Tyr Gln Glu
                 125                 130                 135

 Ser Leu His Cys Val Gln Thr Ala Phe His Ile Leu Ser Gly Gln
                 140                 145                 150

 Gly Asp Val Leu Asn Ile Asp Pro Leu Lys Phe Tyr Thr His Leu
                 155                 160                 165

 Tyr Lys Thr Leu Phe Lys Leu His Ala Gly Ala Thr Asn Glu Gly
                 170                 175                 180

 Val Glu Ile Val Leu Gln Cys Leu Asp Val Met Leu Thr Lys Arg
                 185                 190                 195

 Arg Lys Gln Val Ser Gln Gln Arg Ala Leu Ala Phe Ile Lys Arg
                 200                 205                 210

 Leu Cys Thr Leu Ala Leu His Val Leu Pro Asn Ser Ser Ile Gly
                 215                 220                 225

 Ile Leu Ala Thr Thr Arg Ile Leu Met His Thr Phe Pro Lys Thr
                 230                 235                 240

 Asp Leu Leu Leu Asp Ser Glu Ser Gln Gly Ser Gly Val Phe Leu
                 245                 250                 255

 Pro Glu Leu Asp Glu Pro Glu Tyr Cys Asn Ala Gln Asn Thr Ala
                 260                 265                 270

 Leu Trp Glu Leu His Ala Leu Arg Arg His Tyr His Pro Ile Val
                 275                 280                 285

 Gln Arg Phe Ala Ala His Leu Ile Ala Gly Ala Pro Ser Glu Gly
                 290                 295                 300

 Ser Gly Ala Leu Lys Pro Glu Leu Ser Arg Arg Ser Ala Thr Glu
                 305                 310                 315

 Leu Phe Glu Ala Tyr Ser Met Ala Glu Met Thr Phe Asn Pro Pro
                 320                 325                 330

 Val Glu Ser Ser Asn Pro Lys Ile Lys Gly Lys Phe Leu Gln Gly
                 335                 340                 345

 Asp Ser Phe Leu Asn Glu Asp Leu Asn Gln Leu Ile Lys Arg Tyr
                 350                 355                 360

 Ser Ser Glu Val Ala Thr Glu Ser Pro Leu Asp Phe Thr Lys Tyr
                 365                 370                 375

 Leu Lys Thr Ser Leu His
                 380

<210> 3315
<211> 2912
<212> DNA
<213> Homo sapien

<400> 3315
 aaggcgcggg ccccggcgcg gcggggaggg ctcggccgga ggggaggctg 50

 cggcgcgcgg ccggtcgctg cgggcccggg ccccaagccg tgccgctccg 100

 ctcgcccggg cccagccgag gccgctgcgc ccccgcctcc tcgcgggagg 150

 actcgctcca aactccctga acttcgggga cagtcccccg aagcggcgaa 200

 actctcaggg ttggcaaccc tgcccaggga cccccatccc gggcggcgct 250

 ccggacgccc tcccctcacc gcgcccccgc agacacgtgc ctggactccg 300

 agggcttctg gagccaccgg ccgggccacg atgctcatga ggaaagtgcc 350

 cggcttcgtc ccggcctccc cgtgggggct gcggctgccg cagaagttcc 400

 tcttcctcct cttcctctcg ggcctggtca ccctgtgctt cggggccctc 450

 ttcctgctgc cccactcctc tcgcctcaag cgcctcttcc tggccccccg 500

 gacccagcag cctggtctgg aagtggtggc tgaaatcgcc ggccatgccc 550

 cggcccgcga gcaggagccg cctcccaacc cggcccccgc cgcgccggcc 600

 ccgggcgagg atgaccccag cagctgggcc agtccccgcc gcaggaaagg 650

 ggggctgcgg cgcacccgcc ccactggacc ccgcgaggag gccacggcgg 700

 cccggggcaa tagcatcccg gcctccaggc ccggggacga gggcgtccct 750

 ttccgctttg acttcaacgc attccggagc cgtctccgcc acccggtcct 800

 gggaacgagg gccgatgaga gtcaggagcc ccagagccaa gtgcgagccc 850

 agcgggagaa aatcaaggag atgatgcagt ttgcttggca gagctataag 900

 cgttatgcaa tggggaaaaa cgaactccgt ccactaacaa aagatggcta 950

 cgagggtaac atgttcggag gcctcagcgg ggcaacagtc attgactccc 1000

 tcgataccct ctacctcatg gagctgaagg aggagttcca ggaggccaag 1050

 gcctgggtgg gagagagctt ccacctgaac gtgagcggag aagcatcctt 1100

 gtttgaggtg aacatccgct acatcggggg actcctctca gccttctacc 1150

 tgacaggaga agaggtgttc cgaataaagg ccatcaggct gggagagaag 1200

 ctcctgccgg cgttcaacac ccccacggga atcccaaagg gcgtggtgag 1250

 cttcaaaagt gggaactggg gctgggccac agccggcagc agcagcatct 1300

 tggcggagtt tggatccctg cacttggaat tcttacacct cactgaactc 1350

 tctggcaacc aggtcttcgc tgaaaaggtc aggaacatcc gcaaggtcct 1400

 caggaagatc gaaaagccct ttggcctcta ccccaacttc ctcagcccag 1450

 tgagtgggaa ctgggtgcaa caccatgtct cagttggagg actcggggac 1500

 agtttttatg aatatttgat caaatcctgg ttgatgtcgg gcaagacaga 1550

 tatggaggct aaaaatatgt actacgaagc cttggaggcg atagagacct 1600

 acttgctgaa tgtctctccc ggggggctga cctacattgc cgagtggcga 1650

 ggggggattc tggaccacaa gatggggcac ctggcctgtt tctccggggg 1700

 catgatcgcc cttggcgccg aggatgccaa ggaagaaaag agggcccact 1750

 accgagagct cgcagcccag atcaccaaga cgtgtcacga gtcatacgcc 1800

 cgctcagaca ccaaacttgg gcctgaggcc ttctggttta actccggcag 1850

 agaggccgtg gccacccagc tgagcgagag ctactacatc ctccggccag 1900

 aggtggtgga gagctacatg tacctgtggc gacagaccca caaccccatc 1950

 tacagggagt ggggctggga ggtggtgctg gccttggaga aatactgtcg 2000

 gacagaagcc ggtttctctg ggatccaaga cgtgtacagt agcaccccca 2050

 accacgacaa caagcagcag agcttctttc tagcggagac actaaagtat 2100

 ctctatcttc tgttctctga agatgacttg ctctccctgg aagactgggt 2150

 gttcaacacc gaggcccacc cactcccggt gaaccactca gacagctccg 2200

 gcagagcctg gggcagacac tgaccccatc tcctgccgcc gccctggggc 2250

 cgccgcaggg atgccttgcc ttttcaggat ttgagactgt tctcaaaggg 2300

 attgggaacg aaggccccat ctcgggcaga cccccagcag atgtgtcgga 2350

 caagcaactt cttttcctct gtgaggagac aagacttgga gactcagcga 2400

 tgtcaggcca gggccatggc cacactggcc cacacattcc tttctacaga 2450

 gaatttctat gaagcccact cacttgccat tccagggcca aaggaccgga 2500

 ggtttgcata tccgcccctt gtatttgatt tgcttccttt tggtttcttg 2550

 gtttttgttt ttgcttgatt ttgtcttttc tctacagttt agttttgtca 2600

 caattacaca tatagttttc aaaatcatgc actttctaaa atggtgtcat 2650

 cctgaaaaac aaaacccagt gtttgcacac acacaaaatc ttgaccccgt 2700

 tatctatatt ttaaatgctt tttgcccaac actgacccta tgttcaactt 2750

 tgtgtcattt accttataat ttgaggaggg gtttcccttt gggcctcagt 2800

 gttacaaatt actagtgcta ttttcattat tattgtaatg gaaaaatctg 2850

 tggactagaa taaaagagtt tattgaataa gaaaaaaaaa aaaaaaaaaa 2900

 aaaaaaaaaa aa 2912

<210> 3316
<211> 630
<212> PRT
<213> Homo sapien

<400> 3316
 Met Leu Met Arg Lys Val Pro Gly Phe Val Pro Ala Ser Pro Trp
   1               5                  10                  15

 Gly Leu Arg Leu Pro Gln Lys Phe Leu Phe Leu Leu Phe Leu Ser
                  20                  25                  30

 Gly Leu Val Thr Leu Cys Phe Gly Ala Leu Phe Leu Leu Pro His
                  35                  40                  45

 Ser Ser Arg Leu Lys Arg Leu Phe Leu Ala Pro Arg Thr Gln Gln
                  50                  55                  60

 Pro Gly Leu Glu Val Val Ala Glu Ile Ala Gly His Ala Pro Ala
                  65                  70                  75

 Arg Glu Gln Glu Pro Pro Pro Asn Pro Ala Pro Ala Ala Pro Ala
                  80                  85                  90

 Pro Gly Glu Asp Asp Pro Ser Ser Trp Ala Ser Pro Arg Arg Arg
                  95                 100                 105

 Lys Gly Gly Leu Arg Arg Thr Arg Pro Thr Gly Pro Arg Glu Glu
                 110                 115                 120

 Ala Thr Ala Ala Arg Gly Asn Ser Ile Pro Ala Ser Arg Pro Gly
                 125                 130                 135

 Asp Glu Gly Val Pro Phe Arg Phe Asp Phe Asn Ala Phe Arg Ser
                 140                 145                 150

 Arg Leu Arg His Pro Val Leu Gly Thr Arg Ala Asp Glu Ser Gln
                 155                 160                 165

 Glu Pro Gln Ser Gln Val Arg Ala Gln Arg Glu Lys Ile Lys Glu
                 170                 175                 180

 Met Met Gln Phe Ala Trp Gln Ser Tyr Lys Arg Tyr Ala Met Gly
                 185                 190                 195

 Lys Asn Glu Leu Arg Pro Leu Thr Lys Asp Gly Tyr Glu Gly Asn
                 200                 205                 210

 Met Phe Gly Gly Leu Ser Gly Ala Thr Val Ile Asp Ser Leu Asp
                 215                 220                 225

 Thr Leu Tyr Leu Met Glu Leu Lys Glu Glu Phe Gln Glu Ala Lys
                 230                 235                 240

 Ala Trp Val Gly Glu Ser Phe His Leu Asn Val Ser Gly Glu Ala
                 245                 250                 255

 Ser Leu Phe Glu Val Asn Ile Arg Tyr Ile Gly Gly Leu Leu Ser
                 260                 265                 270

 Ala Phe Tyr Leu Thr Gly Glu Glu Val Phe Arg Ile Lys Ala Ile
                 275                 280                 285

 Arg Leu Gly Glu Lys Leu Leu Pro Ala Phe Asn Thr Pro Thr Gly
                 290                 295                 300

 Ile Pro Lys Gly Val Val Ser Phe Lys Ser Gly Asn Trp Gly Trp
                 305                 310                 315

 Ala Thr Ala Gly Ser Ser Ser Ile Leu Ala Glu Phe Gly Ser Leu
                 320                 325                 330

 His Leu Glu Phe Leu His Leu Thr Glu Leu Ser Gly Asn Gln Val
                 335                 340                 345

 Phe Ala Glu Lys Val Arg Asn Ile Arg Lys Val Leu Arg Lys Ile
                 350                 355                 360

 Glu Lys Pro Phe Gly Leu Tyr Pro Asn Phe Leu Ser Pro Val Ser
                 365                 370                 375

 Gly Asn Trp Val Gln His His Val Ser Val Gly Gly Leu Gly Asp
                 380                 385                 390

 Ser Phe Tyr Glu Tyr Leu Ile Lys Ser Trp Leu Met Ser Gly Lys
                 395                 400                 405

 Thr Asp Met Glu Ala Lys Asn Met Tyr Tyr Glu Ala Leu Glu Ala
                 410                 415                 420

 Ile Glu Thr Tyr Leu Leu Asn Val Ser Pro Gly Gly Leu Thr Tyr
                 425                 430                 435

 Ile Ala Glu Trp Arg Gly Gly Ile Leu Asp His Lys Met Gly His
                 440                 445                 450

 Leu Ala Cys Phe Ser Gly Gly Met Ile Ala Leu Gly Ala Glu Asp
                 455                 460                 465

 Ala Lys Glu Glu Lys Arg Ala His Tyr Arg Glu Leu Ala Ala Gln
                 470                 475                 480

 Ile Thr Lys Thr Cys His Glu Ser Tyr Ala Arg Ser Asp Thr Lys
                 485                 490                 495

 Leu Gly Pro Glu Ala Phe Trp Phe Asn Ser Gly Arg Glu Ala Val
                 500                 505                 510

 Ala Thr Gln Leu Ser Glu Ser Tyr Tyr Ile Leu Arg Pro Glu Val
                 515                 520                 525

 Val Glu Ser Tyr Met Tyr Leu Trp Arg Gln Thr His Asn Pro Ile
                 530                 535                 540

 Tyr Arg Glu Trp Gly Trp Glu Val Val Leu Ala Leu Glu Lys Tyr
                 545                 550                 555

 Cys Arg Thr Glu Ala Gly Phe Ser Gly Ile Gln Asp Val Tyr Ser
                 560                 565                 570

 Ser Thr Pro Asn His Asp Asn Lys Gln Gln Ser Phe Phe Leu Ala
                 575                 580                 585

 Glu Thr Leu Lys Tyr Leu Tyr Leu Leu Phe Ser Glu Asp Asp Leu
                 590                 595                 600

 Leu Ser Leu Glu Asp Trp Val Phe Asn Thr Glu Ala His Pro Leu
                 605                 610                 615

 Pro Val Asn His Ser Asp Ser Ser Gly Arg Ala Trp Gly Arg His
                 620                 625                 630

<210> 3317
<211> 1695
<212> DNA
<213> Homo sapien

<400> 3317
 gttgccgctg cgcacctggc tcaggtgagc tgccccgccc ccgcccggcg 50

 cgagccccag gtcctggcag cagcccctga cctgtccagg tgccctgtcc 100

 agctgactgc aaggacagag aggagtcctg cccagctctt ggatcagtct 150

 gctggccgag gagcccggtg gagccagggg tgaccctgga gcccagcctg 200

 ccccgaggag gccccggctc agagccatgc caggtgtctg tgatagggcc 250

 cctgacttcc tctccccgtc tgaagaccag gtgctgaggc ctgccttggg 300

 cagctcagtg gctctgaact gcacggcttg ggtagtctct gggccccact 350

 gctccctgcc ttcagtccag tggctgaaag acgggcttcc attgggaatt 400

 gggggccact acagcctcca cgagtactcc tgggtcaagg ccaacctgtc 450

 agaggtgctt gtgtccagtg tcctgggggt caacgtgacc agcactgaag 500

 tctatggggc cttcacctgc tccatccaga acatcagctt ctcctccttc 550

 actcttcaga gagctggccc tacaagccac gtggctgcgg tgctggcctc 600

 cctcctggtc ctgctggccc tgctgctggc cgccctgctc tatgtcaagt 650

 gccgtctcaa cgtgctgctc tggtaccagg acgcgtatgg ggaggtggag 700

 ataaacgacg ggaagctcta cgacgcctac gtctcctaca gcgactgccc 750

 cgaggaccgc aagttcgtga acttcatcct aaagccgcag ctggagcggc 800

 gtcggggcta caagctcttc ctggacgacc gcgacctcct gccgcgcgct 850

 gagccctccg ccgacctctt ggtgaacctg agccgctgcc gacgcctcat 900

 cgtggtgctt tcggacgcct tcctgagccg ggcctggtgc agccacagct 950

 tccgggaggg cctgtgccgg ctgctggagc tcacccgcag acccatcttc 1000

 atcaccttcg agggccagag gcgcgacccc gcgcacccgg cgctccgcct 1050

 gctgcgccag caccgccacc tggtgacctt gctgctctgg aggcccggct 1100

 ccgtgactcc ttcctccgat ttttggaaag aagtgcagct ggcgctgccg 1150

 cggaaggtgc ggtacaggcc ggtggaagga gacccccaga cgcagctgca 1200

 ggacgacaag gaccccatgc tgattcttcg aggccgagtc cctgagggcc 1250

 gggccctgga ctcagaggtg gacccggacc ctgagggcga cctgggtgtc 1300

 cgggggcctg tttttggaga gccatcagct ccaccgcaca ccagtggggt 1350

 ctcgctggga gagagccgga gcagcgaagt ggacgtctcg gatctcggct 1400

 cgcgaaacta cagtgcccgc acagacttct actgcctggt gtccaaggat 1450

 gatatgtagc tcccacccca gagtgcagga tcatagggac agcgggggcc 1500

 agggcagcgg cgtcgctcct ctgctcaaca ggaccacaac ccctgccagc 1550

 agccctggga ccctgccagc agccctggga aaaggctgtg gcctcagggc 1600

 gcctcccagt gccagaaaat aaagtccttt tggattctga aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1695

<210> 3318
<211> 410
<212> PRT
<213> Homo sapien

<400> 3318
 Met Pro Gly Val Cys Asp Arg Ala Pro Asp Phe Leu Ser Pro Ser
   1               5                  10                  15

 Glu Asp Gln Val Leu Arg Pro Ala Leu Gly Ser Ser Val Ala Leu
                  20                  25                  30

 Asn Cys Thr Ala Trp Val Val Ser Gly Pro His Cys Ser Leu Pro
                  35                  40                  45

 Ser Val Gln Trp Leu Lys Asp Gly Leu Pro Leu Gly Ile Gly Gly
                  50                  55                  60

 His Tyr Ser Leu His Glu Tyr Ser Trp Val Lys Ala Asn Leu Ser
                  65                  70                  75

 Glu Val Leu Val Ser Ser Val Leu Gly Val Asn Val Thr Ser Thr
                  80                  85                  90

 Glu Val Tyr Gly Ala Phe Thr Cys Ser Ile Gln Asn Ile Ser Phe
                  95                 100                 105

 Ser Ser Phe Thr Leu Gln Arg Ala Gly Pro Thr Ser His Val Ala
                 110                 115                 120

 Ala Val Leu Ala Ser Leu Leu Val Leu Leu Ala Leu Leu Leu Ala
                 125                 130                 135

 Ala Leu Leu Tyr Val Lys Cys Arg Leu Asn Val Leu Leu Trp Tyr
                 140                 145                 150

 Gln Asp Ala Tyr Gly Glu Val Glu Ile Asn Asp Gly Lys Leu Tyr
                 155                 160                 165

 Asp Ala Tyr Val Ser Tyr Ser Asp Cys Pro Glu Asp Arg Lys Phe
                 170                 175                 180

 Val Asn Phe Ile Leu Lys Pro Gln Leu Glu Arg Arg Arg Gly Tyr
                 185                 190                 195

 Lys Leu Phe Leu Asp Asp Arg Asp Leu Leu Pro Arg Ala Glu Pro
                 200                 205                 210

 Ser Ala Asp Leu Leu Val Asn Leu Ser Arg Cys Arg Arg Leu Ile
                 215                 220                 225

 Val Val Leu Ser Asp Ala Phe Leu Ser Arg Ala Trp Cys Ser His
                 230                 235                 240

 Ser Phe Arg Glu Gly Leu Cys Arg Leu Leu Glu Leu Thr Arg Arg
                 245                 250                 255

 Pro Ile Phe Ile Thr Phe Glu Gly Gln Arg Arg Asp Pro Ala His
                 260                 265                 270

 Pro Ala Leu Arg Leu Leu Arg Gln His Arg His Leu Val Thr Leu
                 275                 280                 285

 Leu Leu Trp Arg Pro Gly Ser Val Thr Pro Ser Ser Asp Phe Trp
                 290                 295                 300

 Lys Glu Val Gln Leu Ala Leu Pro Arg Lys Val Arg Tyr Arg Pro
                 305                 310                 315

 Val Glu Gly Asp Pro Gln Thr Gln Leu Gln Asp Asp Lys Asp Pro
                 320                 325                 330

 Met Leu Ile Leu Arg Gly Arg Val Pro Glu Gly Arg Ala Leu Asp
                 335                 340                 345

 Ser Glu Val Asp Pro Asp Pro Glu Gly Asp Leu Gly Val Arg Gly
                 350                 355                 360

 Pro Val Phe Gly Glu Pro Ser Ala Pro Pro His Thr Ser Gly Val
                 365                 370                 375

 Ser Leu Gly Glu Ser Arg Ser Ser Glu Val Asp Val Ser Asp Leu
                 380                 385                 390

 Gly Ser Arg Asn Tyr Ser Ala Arg Thr Asp Phe Tyr Cys Leu Val
                 395                 400                 405

 Ser Lys Asp Asp Met
                 410

<210> 3319
<211> 1066
<212> DNA
<213> Homo sapien

<400> 3319
 ggcagttagt cggctgcaat ggcgccggtg aggcggtccg cgaagtggcg 50

 gcctggtggt attgaggcgc gtggtgaagg ggtttccact gtcgggtaca 100

 ggaataagaa tgtgagacag aagacatggc ggcctaacca cccgcaagcc 150

 ttcgtgggga gcgttcgcga gggacaaggc tttgcttttc gaagaaaact 200

 gaaaatacag caaagttaca agaaattgct acggaaggaa aagaaggctc 250

 aaacgtcact ggaatctcaa ttcacagatc gatacccaga taatctgaaa 300

 catctctatt tagctgaaga ggaaagacat aggaagcaag caagaaaagt 350

 cgaccatcct ttgtcagaac aagttcacca gccgttgctt gaagaacagt 400

 gtagcattga cgagccttta tttgaagatc agtgtagctt tgaccagcct 450

 cagccagaag aacaatgtat taaaacagta aactccttta caatttcaaa 500

 gaaaaataaa aagaaaacat caaatcaaaa agcacaagaa gaatatgaac 550

 agatacaagc caaacgtgct gctaagaaac aagaattcga gaggagaaaa 600

 caggagagag aagaagccca aaggcagtac aaaaagaaga aaatggaagt 650

 gtttaaaata ctgaacaaaa agactaaaaa gggccaacca aacttgaatg 700

 tacaaatgga gtaccttctt caaaaaatac aagaaaaatg ttaaacattt 750

 tgttcctaca ggttaaaata tctgctgcct attaggttct tctgtgacat 800

 gtgcctccca gcagtgaact aaatttgtcg acataaactg gattgctaaa 850

 ctatgctaaa tataagatgt tcacatattt ttattatggt aaaaaatttt 900

 ctaaatatgt tctacatgtt tcttatttat ttgcctctga aggaaggttg 950

 gcctgaagaa ctgaaagaac ctcttatttt gcaagacagg cccaagcatg 1000

 taatactttt gtaccatatg agatttatat gaaataaatt ttttaaaaat 1050

 aaggaaaaaa aaaaaa 1066

<210> 3320
<211> 241
<212> PRT
<213> Homo sapien

<400> 3320
 Met Ala Pro Val Arg Arg Ser Ala Lys Trp Arg Pro Gly Gly Ile
   1               5                  10                  15

 Glu Ala Arg Gly Glu Gly Val Ser Thr Val Gly Tyr Arg Asn Lys
                  20                  25                  30

 Asn Val Arg Gln Lys Thr Trp Arg Pro Asn His Pro Gln Ala Phe
                  35                  40                  45

 Val Gly Ser Val Arg Glu Gly Gln Gly Phe Ala Phe Arg Arg Lys
                  50                  55                  60

 Leu Lys Ile Gln Gln Ser Tyr Lys Lys Leu Leu Arg Lys Glu Lys
                  65                  70                  75

 Lys Ala Gln Thr Ser Leu Glu Ser Gln Phe Thr Asp Arg Tyr Pro
                  80                  85                  90

 Asp Asn Leu Lys His Leu Tyr Leu Ala Glu Glu Glu Arg His Arg
                  95                 100                 105

 Lys Gln Ala Arg Lys Val Asp His Pro Leu Ser Glu Gln Val His
                 110                 115                 120

 Gln Pro Leu Leu Glu Glu Gln Cys Ser Ile Asp Glu Pro Leu Phe
                 125                 130                 135

 Glu Asp Gln Cys Ser Phe Asp Gln Pro Gln Pro Glu Glu Gln Cys
                 140                 145                 150

 Ile Lys Thr Val Asn Ser Phe Thr Ile Ser Lys Lys Asn Lys Lys
                 155                 160                 165

 Lys Thr Ser Asn Gln Lys Ala Gln Glu Glu Tyr Glu Gln Ile Gln
                 170                 175                 180

 Ala Lys Arg Ala Ala Lys Lys Gln Glu Phe Glu Arg Arg Lys Gln
                 185                 190                 195

 Glu Arg Glu Glu Ala Gln Arg Gln Tyr Lys Lys Lys Lys Met Glu
                 200                 205                 210

 Val Phe Lys Ile Leu Asn Lys Lys Thr Lys Lys Gly Gln Pro Asn
                 215                 220                 225

 Leu Asn Val Gln Met Glu Tyr Leu Leu Gln Lys Ile Gln Glu Lys
                 230                 235                 240

 Cys


<210> 3321
<211> 4372
<212> DNA
<213> Homo sapien

<400> 3321
 tagttattaa agttcctatg cagctccgcc tcgcgtccgg cctcatttcc 50

 tcggaaaatc cctgctttcc ccgctcgcca cgccctcctc ctacccggct 100

 ttaaagctag tgaggcacag cctgcgggga acgtagctag ctgcaagcag 150

 aggccggcat gaccaccgag cagcgacgca gcctgcaagc cttccaggat 200

 tatatccgga agaccctgga ccctacctac atcctgagct acatggcccc 250

 ctggtttagg gaggaagagg tgcagtatat tcaggctgag aaaaacaaca 300

 agggcccaat ggaggctgcc acactttttc tcaagttcct gttggagctc 350

 caggaggaag gctggttccg tggctttttg gatgccctag accatgcagg 400

 ttattctgga ctttatgaag ccattgaaag ttgggatttc aaaaaaattg 450

 aaaagttgga ggagtataga ttacttttaa aacgtttaca accagaattt 500

 aaaaccagaa ttatcccaac cgatatcatt tctgatctgt ctgaatgttt 550

 aattaatcag gaatgtgaag aaattctaca gatttgctct actaagggga 600

 tgatggcagg tgcagagaaa ttggtggaat gccttctcag atcagacaag 650

 gaaaactggc ccaaaacttt gaaacttgct ttggagaaag aaaggaacaa 700

 gttcagtgaa ctgtggattg tagagaaagg tataaaagat gttgaaacag 750

 aagatcttga ggataagatg gaaacttctg acatacagat tttctaccaa 800

 gaagatccag aatgccagaa tcttagtgag aattcatgtc caccttcaga 850

 agtgtctgat acaaacttgt acagcccatt taaaccaaga aattaccaat 900

 tagagcttgc tttgcctgct atgaaaggaa aaaacacaat aatatgtgct 950

 cctacaggtt gtggaaaaac ctttgtttca ctgcttatat gtgaacatca 1000

 tcttaaaaaa ttcccacaag gacaaaaggg gaaagttgtc ttttttgcga 1050

 atcagatccc agtgtatgaa cagcagaaat ctgtattctc aaaatacttt 1100

 gaaagacatg ggtatagagt tacaggcatt tctggagcaa cagctgagaa 1150

 tgtcccagtg gaacagattg ttgagaacaa tgacatcatc attttaactc 1200

 cacagattct tgtgaacaac cttaaaaagg gaacgattcc atcactatcc 1250

 atctttactt tgatgatatt tgatgaatgc cacaacacta gtaaacaaca 1300

 cccgtacaat atgatcatgt ttaattatct agatcagaaa cttggaggat 1350

 cttcaggccc actgccccag gtcattgggc tgactgcctc ggttggtgtt 1400

 ggggatgcca aaaacacaga tgaagccttg gattatatct gcaagctgtg 1450

 tgcttctctt gatgcgtcag tgatagcaac agtcaaacac aatctggagg 1500

 aactggagca agttgtttat aagccccaga agtttttcag gaaagtggaa 1550

 tcacggatta gcgacaaatt taaatacatc atagctcagc tgatgaggga 1600

 cacagagagt ctggcaaaga gaatctgcaa agacctcgaa aacttatctc 1650

 aaattcaaaa tagggaattt ggaacacaga aatatgaaca atggattgtt 1700

 acagttcaga aagcatgcat ggtgttccag atgccagaca aagatgaaga 1750

 gagcaggatt tgtaaagccc tgtttttata cacttcacat ttgcggaaat 1800

 ataatgatgc cctcattatc agtgagcatg cacgaatgaa agatgctctg 1850

 gattacttga aagacttctt cagcaatgtc cgagcagcag gattcgatga 1900

 gattgagcaa gatcttactc agagatttga agaaaagctg caggaactag 1950

 aaagtgtttc cagggatccc agcaatgaga atcctaaact tgaagacctc 2000

 tgcttcatct tacaagaaga gtaccactta aacccagaga caataacaat 2050

 tctctttgtg aaaaccagag cacttgtgga cgctttaaaa aattggattg 2100

 aaggaaatcc taaactcagt tttctaaaac ctggcatatt gactggacgt 2150

 ggcaaaacaa atcagaacac aggaatgacc ctcccggcac agaagtgtat 2200

 attggatgca ttcaaagcca gtggagatca caatattctg attgccacct 2250

 cagttgctga tgaaggcatt gacattgcac agtgcaatct tgtcatcctt 2300

 tatgagtatg tgggcaatgt catcaaaatg atccaaacca gaggcagagg 2350

 aagagcaaga ggtagcaagt gcttccttct gactagtaat gctggtgtaa 2400

 ttgaaaaaga acaaataaac atgtacaaag aaaaaatgat gaatgactct 2450

 attttacgcc ttcagacatg ggacgaagca gtatttaggg aaaagattct 2500

 gcatatacag actcatgaaa aattcatcag agatagtcaa gaaaaaccaa 2550

 aacctgtacc tgataaggaa aataaaaaac tgctctgcag aaagtgcaaa 2600

 gccttggcat gttacacagc tgacgtaaga gtgatagagg aatgccatta 2650

 cactgtgctt ggagatgctt ttaaggaatg ctttgtgagt agaccacatc 2700

 ccaagccaaa gcagttttca agttttgaaa aaagagcaaa gatattctgt 2750

 gcccgacaga actgcagcca tgactgggga atccatgtga agtacaagac 2800

 atttgagatt ccagttataa aaattgaaag ttttgtggtg gaggatattg 2850

 caactggagt tcagacactg tactcgaagt ggaaggactt tcattttgag 2900

 aagataccat ttgatccagc agaaatgtcc aaatgatatc aggtcctcaa 2950

 tcttcagcta cagggaatga gtaactttga gtggagaaga aacaaacata 3000

 gtgggtataa tcatggatcg cttgtacccc tgtgaaaata tattttttaa 3050

 aaatatcttt agcagtttgt actatattat atatgcaaag cacaaatgag 3100

 tgaatcacag cactgagtat tttgtaggcc aacagagctc atagtacttg 3150

 ggaaaaatta aaaagcctca tttctagcct tctttttaga gtcaactgcc 3200

 aacaaacaca cagtaatcac tctgtacaca ctgggataga tgaatgaatg 3250

 gaatgttggg aatttttatc tccctttgtc tccttaacct actgtaaact 3300

 ggcttttgcc cttaacaatc tactgaaatt gttcttttga aggttaccag 3350

 tgactctggt tgccaaatcc actgggcact tcttaacctt ctatttgacc 3400

 tctgcgcatt tggccctgtt gagcactctt cttgaagctc tccctgggct 3450

 tctctctctt ctagttctat tctagtcttt ttttattgag tcctcctctt 3500

 tgctgatccc ttccaagggt tcaatatata tacatgtata tactgtacat 3550

 atgtatatgt aactaatata catacataca ggtatgtata tgtaatggtt 3600

 atatgtactc atgttcctgg tgtagcaacg tgtggtatgg ctacacagag 3650

 aacatgagaa cataaagcca tttttatgct tactactaaa agctgtccac 3700

 tgtagagttg ctgtatgtag caatgtgtat ccactctaca gtggtcagct 3750

 tttagtagag agcataaaaa tgataaaata cttcttgaaa acttagttta 3800

 ctatacatct tgccctatta atatgttctc ttaacgtgtg ccattgttct 3850

 ctttgaccat tttcctataa tgatgttgat gttcaacacc tggactgaat 3900

 gtctgttctc agatcccttg gatgttacag atgaggcagt ctgactgtcc 3950

 tttctacttg aaagattaga atatgtatcc aaatggcatt cacgtgtcac 4000

 ttagcaaggt ttgctgatgc ttcaaagagc ttagtttgcg gtttcctgga 4050

 cgtggaaaca agtatctgag ttccctggag atcaacggga tgaggtgtta 4100

 cagctgcctc cctcttcatg caatctggtg agcagtggtg caggcgggga 4150

 gccagagaaa cttgccagtt atataacttc tctttggctt ttcttcatct 4200

 gtaaaacaag gataatactg aactgtaagg gttagtggag agtttttaat 4250

 taaaagaatg tgtgaaaagt acatgacaca gtagttgctt gataatagtt 4300

 actagtagta gtattcttac taagacccaa tacaaatgga ttatttaaac 4350

 caaaaaaaaa aaaaaaaaaa aa 4372

<210> 3322
<211> 925
<212> PRT
<213> Homo sapien

<400> 3322
 Met Thr Thr Glu Gln Arg Arg Ser Leu Gln Ala Phe Gln Asp Tyr
   1               5                  10                  15

 Ile Arg Lys Thr Leu Asp Pro Thr Tyr Ile Leu Ser Tyr Met Ala
                  20                  25                  30

 Pro Trp Phe Arg Glu Glu Glu Val Gln Tyr Ile Gln Ala Glu Lys
                  35                  40                  45

 Asn Asn Lys Gly Pro Met Glu Ala Ala Thr Leu Phe Leu Lys Phe
                  50                  55                  60

 Leu Leu Glu Leu Gln Glu Glu Gly Trp Phe Arg Gly Phe Leu Asp
                  65                  70                  75

 Ala Leu Asp His Ala Gly Tyr Ser Gly Leu Tyr Glu Ala Ile Glu
                  80                  85                  90

 Ser Trp Asp Phe Lys Lys Ile Glu Lys Leu Glu Glu Tyr Arg Leu
                  95                 100                 105

 Leu Leu Lys Arg Leu Gln Pro Glu Phe Lys Thr Arg Ile Ile Pro
                 110                 115                 120

 Thr Asp Ile Ile Ser Asp Leu Ser Glu Cys Leu Ile Asn Gln Glu
                 125                 130                 135

 Cys Glu Glu Ile Leu Gln Ile Cys Ser Thr Lys Gly Met Met Ala
                 140                 145                 150

 Gly Ala Glu Lys Leu Val Glu Cys Leu Leu Arg Ser Asp Lys Glu
                 155                 160                 165

 Asn Trp Pro Lys Thr Leu Lys Leu Ala Leu Glu Lys Glu Arg Asn
                 170                 175                 180

 Lys Phe Ser Glu Leu Trp Ile Val Glu Lys Gly Ile Lys Asp Val
                 185                 190                 195

 Glu Thr Glu Asp Leu Glu Asp Lys Met Glu Thr Ser Asp Ile Gln
                 200                 205                 210

 Ile Phe Tyr Gln Glu Asp Pro Glu Cys Gln Asn Leu Ser Glu Asn
                 215                 220                 225

 Ser Cys Pro Pro Ser Glu Val Ser Asp Thr Asn Leu Tyr Ser Pro
                 230                 235                 240

 Phe Lys Pro Arg Asn Tyr Gln Leu Glu Leu Ala Leu Pro Ala Met
                 245                 250                 255

 Lys Gly Lys Asn Thr Ile Ile Cys Ala Pro Thr Gly Cys Gly Lys
                 260                 265                 270

 Thr Phe Val Ser Leu Leu Ile Cys Glu His His Leu Lys Lys Phe
                 275                 280                 285

 Pro Gln Gly Gln Lys Gly Lys Val Val Phe Phe Ala Asn Gln Ile
                 290                 295                 300

 Pro Val Tyr Glu Gln Gln Lys Ser Val Phe Ser Lys Tyr Phe Glu
                 305                 310                 315

 Arg His Gly Tyr Arg Val Thr Gly Ile Ser Gly Ala Thr Ala Glu
                 320                 325                 330

 Asn Val Pro Val Glu Gln Ile Val Glu Asn Asn Asp Ile Ile Ile
                 335                 340                 345

 Leu Thr Pro Gln Ile Leu Val Asn Asn Leu Lys Lys Gly Thr Ile
                 350                 355                 360

 Pro Ser Leu Ser Ile Phe Thr Leu Met Ile Phe Asp Glu Cys His
                 365                 370                 375

 Asn Thr Ser Lys Gln His Pro Tyr Asn Met Ile Met Phe Asn Tyr
                 380                 385                 390

 Leu Asp Gln Lys Leu Gly Gly Ser Ser Gly Pro Leu Pro Gln Val
                 395                 400                 405

 Ile Gly Leu Thr Ala Ser Val Gly Val Gly Asp Ala Lys Asn Thr
                 410                 415                 420

 Asp Glu Ala Leu Asp Tyr Ile Cys Lys Leu Cys Ala Ser Leu Asp
                 425                 430                 435

 Ala Ser Val Ile Ala Thr Val Lys His Asn Leu Glu Glu Leu Glu
                 440                 445                 450

 Gln Val Val Tyr Lys Pro Gln Lys Phe Phe Arg Lys Val Glu Ser
                 455                 460                 465

 Arg Ile Ser Asp Lys Phe Lys Tyr Ile Ile Ala Gln Leu Met Arg
                 470                 475                 480

 Asp Thr Glu Ser Leu Ala Lys Arg Ile Cys Lys Asp Leu Glu Asn
                 485                 490                 495

 Leu Ser Gln Ile Gln Asn Arg Glu Phe Gly Thr Gln Lys Tyr Glu
                 500                 505                 510

 Gln Trp Ile Val Thr Val Gln Lys Ala Cys Met Val Phe Gln Met
                 515                 520                 525

 Pro Asp Lys Asp Glu Glu Ser Arg Ile Cys Lys Ala Leu Phe Leu
                 530                 535                 540

 Tyr Thr Ser His Leu Arg Lys Tyr Asn Asp Ala Leu Ile Ile Ser
                 545                 550                 555

 Glu His Ala Arg Met Lys Asp Ala Leu Asp Tyr Leu Lys Asp Phe
                 560                 565                 570

 Phe Ser Asn Val Arg Ala Ala Gly Phe Glu Glu Ile Glu Gln Asp
                 575                 580                 585

 Leu Thr Gln Arg Phe Glu Glu Lys Leu Gln Glu Leu Glu Ser Val
                 590                 595                 600

 Ser Arg Asp Pro Ser Asn Glu Asn Pro Lys Leu Glu Asp Leu Cys
                 605                 610                 615

 Phe Ile Leu Gln Glu Glu Tyr His Leu Asn Pro Glu Thr Ile Thr
                 620                 625                 630

 Ile Leu Phe Val Lys Thr Arg Ala Leu Val Asp Ala Leu Lys Asn
                 635                 640                 645

 Trp Ile Glu Gly Asn Pro Lys Leu Ser Phe Leu Lys Pro Gly Ile
                 650                 655                 660

 Leu Thr Gly Arg Gly Lys Thr Asn Gln Asn Thr Gly Met Thr Leu
                 665                 670                 675

 Pro Ala Gln Lys Cys Ile Leu Asp Ala Phe Lys Ala Ser Gly Asp
                 680                 685                 690

 His Asn Ile Leu Ile Ala Thr Ser Val Ala Asp Glu Gly Ile Asp
                 695                 700                 705

 Ile Ala Gln Cys Asn Leu Val Ile Leu Tyr Glu Tyr Val Gly Asn
                 710                 715                 720

 Val Ile Lys Met Ile Gln Thr Arg Gly Arg Gly Arg Ala Arg Gly
                 725                 730                 735

 Ser Lys Cys Phe Leu Leu Thr Ser Asn Ala Gly Val Ile Glu Lys
                 740                 745                 750

 Glu Gln Ile Asn Met Tyr Lys Glu Lys Met Met Asn Asp Ser Ile
                 755                 760                 765

 Leu Arg Leu Gln Thr Trp Asp Glu Ala Val Phe Arg Glu Lys Ile
                 770                 775                 780

 Leu His Ile Gln Thr His Glu Lys Phe Ile Arg Asp Ser Gln Glu
                 785                 790                 795

 Lys Pro Lys Pro Val Pro Asp Lys Glu Asn Lys Lys Leu Leu Cys
                 800                 805                 810

 Arg Lys Cys Lys Ala Leu Ala Cys Tyr Thr Ala Asp Val Arg Val
                 815                 820                 825

 Ile Glu Glu Cys His Tyr Thr Val Leu Gly Asp Ala Phe Lys Glu
                 830                 835                 840

 Cys Phe Val Ser Arg Pro His Pro Lys Pro Lys Gln Phe Ser Ser
                 845                 850                 855

 Phe Glu Lys Arg Ala Lys Ile Phe Cys Ala Arg Gln Asn Cys Ser
                 860                 865                 870

 His Asp Trp Gly Ile His Val Lys Tyr Lys Thr Phe Glu Ile Pro
                 875                 880                 885

 Val Ile Lys Ile Glu Ser Phe Val Val Glu Asp Ile Ala Thr Gly
                 890                 895                 900

 Val Gln Thr Leu Tyr Ser Lys Trp Lys Asp Phe His Phe Glu Lys
                 905                 910                 915

 Ile Pro Phe Asp Pro Ala Glu Met Ser Lys
                 920                 925

<210> 3323
<211> 1203
<212> DNA
<213> Homo sapien

<400> 3323
 catctggtgt attgactgtg gccagtctta aagctagttt ttgctatgtg 50

 gaacatgctg ctctaattca gatttaaaga gtttcttcct gttaattcga 100

 agctcactgt gcctcttgtt tccgagggaa gaaggactga ttaagtcatc 150

 taaatggatg caatactgaa ttacaggtca gaagatactg aagattacta 200

 cacattactg ggatgtgatg aactatcttc ggttgaacaa atcctggcag 250

 aatttaaagt cagagctctg gaatgtcacc cagacaagca tcctgaaaac 300

 cccaaagctg tggagacttt tcagaaactg cagaaggcaa aggagattct 350

 gaccaatgaa gagagtcgag cccgctatga ccactggcga aggagccaga 400

 tgtcgatgcc attccagcag tgggaagctt tgaatgactc agtgaagacg 450

 tcaatgcact gggttgtcag aggtaaaaaa gacctgatgc tggaagaatc 500

 tgacaagact cataccacca agatggaaaa tgaggaatgt aatgagcaaa 550

 gagaaagaaa gaaagaggag ctggcttcaa ccgcagagaa aacggagcag 600

 aaagaaccca agcccctaga gaagtcagtc tccccgcaaa attcagattc 650

 ttcaggtttt gcagatgtga atggttggca ccttcgtttc cgctggtcca 700

 aggatgctcc ctcagaactc ctgaggaagt tcagaaacta tgaaatatga 750

 aatatctctg cttcaaaaaa tgaggaagag caagactgtc ccctatgctg 800

 ccaacatgca gtctttgttt atgtcttaaa aatgtcatgt ttatgtcatg 850

 tctgtgaatt gctgagtact aattgattcc tccatccttg aatcagttct 900

 cataatgctt tttaaataag aaaaattcag aagatgaatt tcttccaata 950

 tttgaataaa ttaaagctct tagatacaga gtagattgta ttatatgctt 1000

 tttcctatta atactactta tagaaatcca ttaaaaagca atctctgtac 1050

 agtgtattta aatatttcat tgacatactg tgatctctat tagtgatgga 1100

 tgtacaaaaa atgttttctt acccttgact tacaatgaaa tgtgaaatta 1150

 cttgtctgaa ccccgtgggg agaaataaat aattttccca aagttcaaaa 1200

 aaa 1203

<210> 3324
<211> 198
<212> PRT
<213> Homo sapien

<400> 3324
 Met Asp Ala Ile Leu Asn Tyr Arg Ser Glu Asp Thr Glu Asp Tyr
   1               5                  10                  15

 Tyr Thr Leu Leu Gly Cys Asp Glu Leu Ser Ser Val Glu Gln Ile
                  20                  25                  30

 Leu Ala Glu Phe Lys Val Arg Ala Leu Glu Cys His Pro Asp Lys
                  35                  40                  45

 His Pro Glu Asn Pro Lys Ala Val Glu Thr Phe Gln Lys Leu Gln
                  50                  55                  60

 Lys Ala Lys Glu Ile Leu Thr Asn Glu Glu Ser Arg Ala Arg Tyr
                  65                  70                  75

 Asp His Trp Arg Arg Ser Gln Met Ser Met Pro Phe Gln Gln Trp
                  80                  85                  90

 Glu Ala Leu Asn Asp Ser Val Lys Thr Ser Met His Trp Val Val
                  95                 100                 105

 Arg Gly Lys Lys Asp Leu Met Leu Glu Glu Ser Asp Lys Thr His
                 110                 115                 120

 Thr Thr Lys Met Glu Asn Glu Glu Cys Asn Glu Gln Arg Glu Arg
                 125                 130                 135

 Lys Lys Glu Glu Leu Ala Ser Thr Ala Glu Lys Thr Glu Gln Lys
                 140                 145                 150

 Glu Pro Lys Pro Leu Glu Lys Ser Val Ser Pro Gln Asn Ser Asp
                 155                 160                 165

 Ser Ser Gly Phe Ala Asp Val Asn Gly Trp His Leu Arg Phe Arg
                 170                 175                 180

 Trp Ser Lys Asp Ala Pro Ser Glu Leu Leu Arg Lys Phe Arg Asn
                 185                 190                 195

 Tyr Glu Ile


<210> 3325
<211> 600
<212> DNA
<213> Homo sapien

<400> 3325
 agtcttggcg gaggtgacca aagccacgta atgtccgtag ttcgctcatc 50

 cgtccatgcc agatggattg tggggaaggt gattgggaca aaaatgcaaa 100

 agactgctaa agtgagagtg accaggcttg ttctggatcc ctatttatta 150

 aagtatttta ataagcggaa aacctacttt gctcacgatg cccttcagca 200

 gtgcacagtt ggggatattg tgcttctcag agctttacct gttccacgag 250

 caaagcatgt gaaacatgaa ctggctgaga tcgttttcaa agttggaaaa 300

 gtcatagatc cagtgacagg aaagccctgt gctggaacta cctacctgga 350

 gagtccgttg agttcggaaa ccacccagct aagcaaaaat ctggaagaac 400

 tcaatatctc ttcagcacag tgaagcggga gtggaagaag gatctaaagg 450

 gaaaaactga catgtttatg ttatggaaaa agaaattttt ctaagtttca 500

 tcacaaactg tgtccagttt ctctgtggtg tttatgaaat agctaaaagc 550

 aaatgaagta aagggcatac tatggttttt cacaaaaaaa aaaaaaaaaa 600

<210> 3326
<211> 130
<212> PRT
<213> Homo sapien

<400> 3326
 Met Ser Val Val Arg Ser Ser Val His Ala Arg Trp Ile Val Gly
   1               5                  10                  15

 Lys Val Ile Gly Thr Lys Met Gln Lys Thr Ala Lys Val Arg Val
                  20                  25                  30

 Thr Arg Leu Val Leu Asp Pro Tyr Leu Leu Lys Tyr Phe Asn Lys
                  35                  40                  45

 Arg Lys Thr Tyr Phe Ala His Asp Ala Leu Gln Gln Cys Thr Val
                  50                  55                  60

 Gly Asp Ile Val Leu Leu Arg Ala Leu Pro Val Pro Arg Ala Lys
                  65                  70                  75

 His Val Lys His Glu Leu Ala Glu Ile Val Phe Lys Val Gly Lys
                  80                  85                  90

 Val Ile Asp Pro Val Thr Gly Lys Pro Cys Ala Gly Thr Thr Tyr
                  95                 100                 105

 Leu Glu Ser Pro Leu Ser Ser Glu Thr Thr Gln Leu Ser Lys Asn
                 110                 115                 120

 Leu Glu Glu Leu Asn Ile Ser Ser Ala Gln
                 125                 130

<210> 3327
<211> 6036
<212> DNA
<213> Homo sapien

<400> 3327
 agcgggctgg gtcctaggcc aggtctgggg taacctggaa cttccacctg 50

 ggctctgcgc taggtctctg tttcactccc tccccgcggg gcgcgcagct 100

 cgcgggtctt tggacaccac cggtcctgag tccgcggact gccattttca 150

 ttaagaactg ccacttagag gtaccaaaat aaagggtatt tgctaccttt 200

 aatacttgcc agttcaggtt ggaggcacag gcagcagcaa gaatggaaag 250

 aaatgttctt acaacatttt cacaggaaat gtcccagtta attttgaatg 300

 aaatgccaaa agctgaatat tccagtttat tcaatgattt tgttgaatct 350

 gaattttttt tgattgatgg ggattcatta cttatcacat gtatctgtga 400

 gatatcattt aagcctgggc agaacctcca tttcttctat ctggttgaac 450

 gctatcttgt ggatcttatt agcaaaggag gacaattcac catagttttc 500

 ttcaaggatg ccgagtatgc gtatttcaac ttccctgaac ttctttcttt 550

 gagaactgct ttaattcttc atcttcagaa gaataccacc attgatgttc 600

 gaacaacatt ttcgagatgc ttatcaaaag agtggggaag tttcttggaa 650

 gagagttacc catatttcct gatagttgca gacgaaggcc tgaacgatct 700

 acaaacacag cttttcaact ttttaatcat tcattcttgg gcaaggaagg 750

 tcaacgttgt actttcctca gggcaagaat ctgatgttct ttgcctttat 800

 gcataccttc ttccaagcat gtacagacac cagatttttt cctggaagaa 850

 taagcagaac attaaagatg cttatacaac cctgcttaac cagttggaaa 900

 gatttaagct ttcagcatta gcacctcttt ttggaagttt aaaatggaat 950

 aatattacgg aagaggcaca caagactgta tctctgctta cacaagtctg 1000

 gccagaagga tctgacattc ggcgtgtctt ttgtgttact tcatgctcat 1050

 tatctttgag aatgtaccat cgctttttag gaaacagaga gccctcctct 1100

 ggtcaggaaa ctgagatcca acaggtgaac agtaattgct taaccctgca 1150

 ggagatggaa gatttgtgta aactgcattg tctcactgtg gtttttctac 1200

 tccatctgcc tctttctcaa agagcttgtg ctagagtcat cacttcacat 1250

 tgggctgagg acatgaagcc tttattacaa atgaaaaagt ggtgtgaata 1300

 tttcatctta agaaatatac atacttttga attttggaat ctgaatttaa 1350

 ttcacctttc tgacttaaat gatgagcttt tgttgaagaa tattgctttt 1400

 tactatgaaa atgaaaatgt aaaaggccta catttgaatt tgggagatac 1450

 cattatgaaa gattatgaat atctctggaa taccgtatca aagttggtca 1500

 gagactttga ggttggacag ccatttcctc tgagaacaac aaaagtttgt 1550

 tttcttggaa agaaaccatc accaatcaaa gacagctcca atgaaatggt 1600

 gcccaatttg ggttttattc caacgtcatc ttttgtggtt gataaatttg 1650

 ctggagatat tttgaaagat ttgccttttc taaagagtga tgatcctatt 1700

 gttacttcac tggttaaaca aaaggaattt gatgaacttg tgcactggca 1750

 ttctcataaa cccctgagtg atgattatga caggtccagg tgtcagtttg 1800

 atgaaaaatc tagagaccct cgtgttctta gatctgtgca aaagtatcat 1850

 gttttccaac ggttttatgg gaattcatta gaaacagtct cttcgaaaat 1900

 catcgtgact caaactatta agtcaaagaa ggattttagt gggcccaaga 1950

 gcaaaaaggc acacgagacc aaggctgaaa taattgctag agagaataag 2000

 aaaaggttat ttgccaggga agaacaaaag gaagagcaaa agtggaatgc 2050

 tttgtcattt tctattgaag agcaattgaa agaaaattta cactctggaa 2100

 taaagagcct ggaagatttt ttgaaatcct gtaaaagtag ctgtgtgaaa 2150

 cttcaggttg aaatggtggg gttaactgct tgcttgaaag cctggaaaga 2200

 acattgccga agtgaagaag gtaaaaccac gaaagattta agtatagctg 2250

 ttcaggtgat gaaaaggatc cactccttga tggaaaaata ctcagaactt 2300

 ttacaagaag atgatcggca actcatagcc agatgcctta agtatttagg 2350

 atttgatgag ttggcaagtt ctttacatcc agcccaggat gcagaaaatg 2400

 atgtaaaagt gaagaaaagg aataaatatt caattggcat tgggccagct 2450

 cggttccaac tgcaatacat gggccattat ttgatacgag atgagagaaa 2500

 agacccagat cccagggtcc aggattttat tcccgacaca tggcagcgag 2550

 agctccttga tgttgtggat aagaatgagt cagcagtgat tgttgcccca 2600

 acgtcctcag gcaaaacata tgcctcctac tactgtatgg agaaagtgct 2650

 gaaggagagc gacgacgggg tggtcgtgta cgttgcaccc acaaaggccc 2700

 ttgttaatca agtggcagca actgttcaga atcgttttac gaaaaatctg 2750

 ccaagtggtg aagttctctg tggtgttttc accagggagt atcgtcatga 2800

 tgccttaaac tgtcaggtac ttattacagt gcctgcctgc tttgaaattc 2850

 tgctgcttgc tcctcatcgc caaaactggg tgaaaaagat cagatatgtt 2900

 atatttgatg aggttcattg tcttggtgga gaaattggag cagaaatctg 2950

 ggaacatctc cttgtcatga tccgatgtcc ctttttggct ctttcagcta 3000

 ccataagtaa tcctgaacat ctcaccgagt ggctacaatc ggtaaaatgg 3050

 tactggaaac aagaagacaa aataattgaa aataataccg cttctaaaag 3100

 acatgtgggt cgtcaggccg gctttcccaa agactacttg caagtaaaac 3150

 aatcgtataa agttagactt gtgctctatg gagagaggta taatgatcta 3200

 gagaagcatg tatgttcaat aaaacatggt gacattcatt ttgatcattt 3250

 tcacccatgt gctgcactaa caacagatca tattgaaagg tatggattcc 3300

 ctcctgatct taccctttca cctcgagaaa gcatccagct gtatgatgcc 3350

 atgtttcaaa tttggaaaag ttggcctcgg gcccaggaac tgtgcccaga 3400

 aaacttcatt cattttaaca ataaattagt cattaaaaag atggatgcta 3450

 ggaaatatga agagagtcta aaggcagaat taacaagttg gattaaaaat 3500

 ggcaacgtag agcaggccag aatggtactt cagaatctta gtcctgaagc 3550

 agatttgagt ccagaaaaca tgatcaccat gtttccactt ctagttgaaa 3600

 aactaaggaa aatggagaag ttacctgcac tatttttttt attcaagtta 3650

 ggagctgtag aaaacgcagc tgaaagtgtg agcactttcc taaagaaaaa 3700

 gcaggagaca aaaaggcctc ccaaagctga taaagaagcc catgtcatgg 3750

 ctaacaaact tcgaaaagtt aaaaaatcca tagagaaaca aaagatcata 3800

 gatgaaaaga gccagaaaaa aaccagaaat gtggatcaaa gcctaataca 3850

 tgaagctgaa catgataatc tagtgaagtg tctagagaag aacctggaaa 3900

 tcccacagga ctgcacatat gctgatcaaa aagcagtgga cactgagact 3950

 ttgcagaagg tatttggtcg agtaaaattt gaaagaaaag gtgaagaatt 4000

 gaaagccttg gcagaaaggg gtattggata tcatcacagt gctatgagtt 4050

 tcaaagaaaa acaattagtt gaaatcctct ttagaaaagg atatcttagg 4100

 gtggtgacag ctactggaac acttgcttta ggtgtcaaca tgccttgtaa 4150

 atctgtggtt tttgctcaaa actcagtcta tctggatgcg ttgaattata 4200

 gacagatgtc tggccgtgct ggaagaagag gtcaagacct gatgggagat 4250

 gtatatttct ttgatattcc attccccaaa ataggaaaac tcataaaatc 4300

 caatgttcct gagctgagag gacacttccc tctcagcata accctggtcc 4350

 tgcgactcat gctgctggct tccaagggag atgacccaga ggataccaag 4400

 gcaaaggtgc tatcagtgct aaagcattca ttgctgtcct tcaagcaacc 4450

 cagagtcatg gacatgttaa aactttactt cctgttttct ttgcagttcc 4500

 tggtgaaaga gggctattta gatcaagaag gtaatcctat ggggtttgct 4550

 ggacttgtat cacatttgca ttatcatgaa ccttctaatc ttgtttttgt 4600

 cagttttctt gtaaatggac tcttccatga tctctgtcag ccaaccagga 4650

 aaggctcaaa acatttttct caagacgtta tggaaaagct agtattagta 4700

 ttggcacatc tctttggaag aagatatttt ccaccaaagt tccaagatgc 4750

 acacttcgag ttttatcaat caaaggtgtt ccttgatgat ctccctgagg 4800

 attttagtga tgctttagat gaatataaca tgaaaattat ggaggacttt 4850

 accactttcc tacgaattgt ttccaaactg gctgatatga atcaggaata 4900

 tcaactccca ttgtcaaaaa tcaaattcac aggtaaagaa tgtgaagact 4950

 ctcaactcgt atctcatttg atgagctgca aggaaggaag agtagcaatt 5000

 tcaccatttg tttgtctgtc tgggaacttt gatgatgatt tgcttcgact 5050

 agaaactcca aaccatgtta ctctaggcac aatcggtgtc aatcgctctc 5100

 aggctccagt gctgttgtca cagaaatttg ataaccgagg aaggaaaatg 5150

 tcgcttaatg cctatgcact ggatttctac aaacatggtt ccttgatagg 5200

 attagtccag gataacagga tgaatgaagg agatgcttat tatttgttga 5250

 aggattttgc actcaccatt aaatctatca gtgtttcctt gcgtgagcta 5300

 tgtgaaaatg aagacgacaa cgttgtctta gcctttgaac aactgagtac 5350

 aactttttgg gaaaagttaa acaaagtcta aaaacaaagt ctatgcaaac 5400

 cacttaaaaa taattccata gtagtttttc aggtcacgtt tttgattctt 5450

 atgcttcttg ccagaaatac attatgataa agtggaaata cattacgatg 5500

 aagtggaaag agcaaacact ttggaatcaa acagagttgc aatcaaacct 5550

 gcaatgttct gtcatgaata ctcacaaatt atttagtata cctgaatctt 5600

 ggtttctttt tataactgag taataatggt tacatctcag gtagtttgag 5650

 gattgactaa aaaaatgcga gaatgttgta tgtgactgaa taacaatttt 5700

 tactctgcga agccaaagta aatataatat tatcagtaac tttatcccca 5750

 gtgtcagtat ttataaaatg tttattaagg ctagaaaaaa tgaatacaat 5800

 atcctgaagg tgaaatatat tctcttcaat tagcataaat atgatttaca 5850

 taagttagct atacagctat tgagatagta ctttctagta aacttaaact 5900

 actttttaaa catacatttt gtgatgattt aacaaaaata tagagaatga 5950

 tttgctttat tgtaattgta tataagtgac tggaaaagca caaagaaata 6000

 aagtgggttc gatctgttaa ataaaaaaaa aaaaaa 6036

<210> 3328
<211> 391
<212> PRT
<213> Homo sapien

<400> 3328
 Met Ser Gly Arg Ala Gly Arg Arg Gly Gln Asp Leu Met Gly Asp
   1               5                  10                  15

 Val Tyr Phe Phe Asp Ile Pro Phe Pro Lys Ile Gly Lys Leu Ile
                  20                  25                  30

 Lys Ser Asn Val Pro Glu Leu Arg Gly His Phe Pro Leu Ser Ile
                  35                  40                  45

 Thr Leu Val Leu Arg Leu Met Leu Leu Ala Ser Lys Gly Asp Asp
                  50                  55                  60

 Pro Glu Asp Ala Lys Ala Lys Val Leu Ser Val Leu Lys His Ser
                  65                  70                  75

 Leu Leu Ser Phe Lys Gln Pro Arg Val Met Asp Met Leu Lys Leu
                  80                  85                  90

 Tyr Phe Leu Phe Ser Leu Gln Phe Leu Val Lys Glu Gly Tyr Leu
                  95                 100                 105

 Asp Gln Glu Gly Asn Pro Met Gly Phe Ala Gly Leu Val Ser His
                 110                 115                 120

 Leu His Tyr His Glu Pro Ser Asn Leu Val Phe Val Ser Phe Leu
                 125                 130                 135

 Val Asn Gly Leu Phe His Asp Leu Cys Gln Pro Thr Arg Lys Gly
                 140                 145                 150

 Ser Lys His Phe Ser Gln Asp Val Met Glu Lys Leu Val Leu Val
                 155                 160                 165

 Leu Ala His Leu Phe Gly Arg Arg Tyr Phe Pro Pro Lys Phe Gln
                 170                 175                 180

 Asp Ala His Phe Glu Phe Tyr Gln Ser Lys Val Phe Leu Asp Asp
                 185                 190                 195

 Leu Pro Glu Asp Phe Ser Asp Ala Leu Asp Glu Tyr Asn Met Lys
                 200                 205                 210

 Ile Met Glu Asp Phe Thr Thr Phe Leu Arg Ile Val Ser Lys Leu
                 215                 220                 225

 Ala Asp Met Asn Gln Glu Tyr Gln Leu Pro Leu Ser Lys Ile Lys
                 230                 235                 240

 Phe Thr Gly Lys Glu Cys Glu Asp Ser Gln Leu Val Ser His Leu
                 245                 250                 255

 Met Ser Cys Lys Glu Gly Arg Val Ala Ile Ser Pro Phe Val Cys
                 260                 265                 270

 Leu Ser Gly Asn Phe Asp Asp Asp Leu Leu Arg Leu Glu Thr Pro
                 275                 280                 285

 Asn His Val Thr Leu Gly Thr Ile Gly Val Asn Arg Ser Gln Ala
                 290                 295                 300

 Pro Val Leu Leu Ser Gln Lys Phe Asp Asn Arg Gly Arg Lys Met
                 305                 310                 315

 Ser Leu Asn Ala Tyr Ala Leu Asp Phe Tyr Lys His Gly Ser Leu
                 320                 325                 330

 Ile Gly Leu Val Gln Asp Asn Arg Met Asn Glu Gly Asp Ala Tyr
                 335                 340                 345

 Tyr Leu Leu Lys Asp Phe Ala Leu Thr Ile Lys Ser Ile Ser Val
                 350                 355                 360

 Ser Leu Arg Glu Leu Cys Glu Asn Glu Asp Asp Asn Val Val Leu
                 365                 370                 375

 Ala Phe Glu Gln Leu Ser Thr Thr Phe Trp Glu Lys Leu Asn Lys
                 380                 385                 390

 Val


<210> 3329
<211> 2952
<212> DNA
<213> Homo sapien

<400> 3329
 aactgatcgc ggcctagtcc cgacgcgtgt gtgctagtga gccggagccg 50

 gcgacggcgg cagtggcggc ccggcctgca ggagcccgac ggggtctctg 100

 ccatggggga gtgacgcgcc tgcacccgct gttccgcggc agcggcgaga 150

 catgaggaga ccccgcgaca ggggcagcgg cggcggctcg tgagccccgg 200

 gatggaggag aaatacggcg gggacgtgct ggccggcccc ggcggcggcg 250

 gcggccttgg gccggtggac gtacccagcg ctcgattaac aaaatatatt 300

 gtgttactat gtttcactaa atttttgaag gctgtgggac ttttcgaatc 350

 atatgatctc ctaaaagctg ttcacattgt tcagttcatt tttatattaa 400

 aacttgggac tgcatttttt atggttttgt ttcaaaagcc attttcttct 450

 gggaaaacta ttaccaaaca ccagtggatc aaaatattta aacatgcagt 500

 tgctgggtgt attatttcac tcttgtggtt ttttggcctc actctttgtg 550

 gaccactaag gactttgctg ctatttgagc acagtgatat tgttgtcatt 600

 tcactactca gtgttttgtt caccagttct ggaggaggac cagcaaagac 650

 aaggggagct gcttttttca ttattgctgt gatctgttta ttgctttttg 700

 acaatgatga tctcatggct aaaatggctg aacaccctga aggacatcat 750

 gacagtgctc taactcatat gctttacaca gccattgcct tcttaggtgt 800

 ggcagatcac aagggtggag tattattgct agtactggct ttgtgttgta 850

 aagttggttt tcatacagct tccagaaagc tctctgtcga cgttggtgga 900

 gctaaacgtc ttcaagcttt atctcatctt gtttctgtgc ttctcttgtg 950

 cccatgggtc attgttcttt ctgtgacaac tgagagtaaa gtggagtctt 1000

 ggttttctct cattatgcct tttgcaacgg ttatcttttt tgtcatgatc 1050

 ctggatttct acgtggattc catttgttca gtcaaaatgg aagtttccaa 1100

 atgtgctcgt tatggatcct ttcccatttt tattagtgct ctcctttttg 1150

 gaaatttttg gacacatcca ataacagacc agcttcgggc tatgaacaaa 1200

 gcagcacacc aggagagcac tgaacacgtc ctgtctggag gagtggtagt 1250

 gagtgctata ttcttcattt tgtctgccaa tatcttatca tctccctcta 1300

 agagaggaca aaaaggtacc cttattggat attctcctga aggaacacct 1350

 ctttataact tcatgggtga tgcttttcag catagctctc aatcgatccc 1400

 taggtttatt aaggaatcac taaaacaaat tcttgaggag agtgactcta 1450

 ggcagatctt ttacttcttg tgcttgaatc tgctttttac ctttgtggaa 1500

 ttattctatg gcgtgctgac caatagtctg ggcctgatct cggatggatt 1550

 ccacatgctt tttgactgct ctgctttagt catgggactt tttgctgccc 1600

 tgatgagtag gtggaaagcc actcggattt tctcctatgg gtacggccga 1650

 atagaaattc tgtctggatt tattaatgga ctttttctaa tagtaatagc 1700

 gttttttgtg tttatggagt cagtggctag attgattgat cctccagaat 1750

 tagacactca catgttaaca ccagtctcag ttggagggct gatagtaaac 1800

 cttattggta tctgtgcctt tagccatgcc catagccatg cccatggagc 1850

 ttctcaagga agctgtcact catctgatca cagccattca caccatatgc 1900

 atggacacag tgaccatggg catggtcaca gccacggatc tgcgggtgga 1950

 ggcatgaatg ctaacatgag gggtgtattt ctacatgttt tggcagatac 2000

 tcttggcagc attggtgtga tcgtatccac agttcttata gagcagtttg 2050

 gatggttcat cgctgaccca ctctgttctc tttttattgc tatattaata 2100

 tttctcagtg ttgttccact gattaaagat gcctgccagg ttctactcct 2150

 gagattgcca ccagaatatg aaaaagaact acatattgct ttagaaaaga 2200

 tacagaaaat tgaaggatta atatcatacc gagaccctca tttttggcgt 2250

 cattctgcta gtattgtggc aggaacaatt catatacagg tgacatctga 2300

 tgtgctagaa caaagaatag tacagcaggt tacaggaata cttaaagatg 2350

 ctggagtaaa caatttaaca attcaagtgg aaaaggaggc atactttcaa 2400

 catatgtctg gcctaagtac tggatttcat gatgttctgg ctatgacaaa 2450

 acaaatggaa tccatgaaat actgcaaaga tggtacttac atcatgtgag 2500

 ataactcaag aattacccct ggagaataaa caatgaagat taaatgactc 2550

 agtatttgta atattgccag aaggataaaa attacacatt aactgtacag 2600

 aaacagagtt ccctactact ggatcaagga atctttcttg aaggaaattt 2650

 aaatacagaa tgaaacatta atggtaaaag tggagtaatt atttaaatta 2700

 tgtgtataaa aggaatcaaa ttttgagtaa acatgatgta ttacatcatc 2750

 ttcgaaaata gatatgatgg attctagtga agaccaaaat tacttctgtt 2800

 tactttctat caggaagcat ctccattgta aatatgtatt tacatgttta 2850

 ttacaaagac ccaaatgaaa aatttttagt ccattttttg catagcctaa 2900

 agataaaata ggaataaaag ttctatattt atggaaaaaa aaaaaaaaaa 2950

 aa 2952

<210> 3330
<211> 765
<212> PRT
<213> Homo sapien

<400> 3330
 Met Glu Glu Lys Tyr Gly Gly Asp Val Leu Ala Gly Pro Gly Gly
   1               5                  10                  15

 Gly Gly Gly Leu Gly Pro Val Asp Val Pro Ser Ala Arg Leu Thr
                  20                  25                  30

 Lys Tyr Ile Val Leu Leu Cys Phe Thr Lys Phe Leu Lys Ala Val
                  35                  40                  45

 Gly Leu Phe Glu Ser Tyr Asp Leu Leu Lys Ala Val His Ile Val
                  50                  55                  60

 Gln Phe Ile Phe Ile Leu Lys Leu Gly Thr Ala Phe Phe Met Val
                  65                  70                  75

 Leu Phe Gln Lys Pro Phe Ser Ser Gly Lys Thr Ile Thr Lys His
                  80                  85                  90

 Gln Trp Ile Lys Ile Phe Lys His Ala Val Ala Gly Cys Ile Ile
                  95                 100                 105

 Ser Leu Leu Trp Phe Phe Gly Leu Thr Leu Cys Gly Pro Leu Arg
                 110                 115                 120

 Thr Leu Leu Leu Phe Glu His Ser Asp Ile Val Val Ile Ser Leu
                 125                 130                 135

 Leu Ser Val Leu Phe Thr Ser Ser Gly Gly Gly Pro Ala Lys Thr
                 140                 145                 150

 Arg Gly Ala Ala Phe Phe Ile Ile Ala Val Ile Cys Leu Leu Leu
                 155                 160                 165

 Phe Asp Asn Asp Asp Leu Met Ala Lys Met Ala Glu His Pro Glu
                 170                 175                 180

 Gly His His Asp Ser Ala Leu Thr His Met Leu Tyr Thr Ala Ile
                 185                 190                 195

 Ala Phe Leu Gly Val Ala Asp His Lys Gly Gly Val Leu Leu Leu
                 200                 205                 210

 Val Leu Ala Leu Cys Cys Lys Val Gly Phe His Thr Ala Ser Arg
                 215                 220                 225

 Lys Leu Ser Val Asp Val Gly Gly Ala Lys Arg Leu Gln Ala Leu
                 230                 235                 240

 Ser His Leu Val Ser Val Leu Leu Leu Cys Pro Trp Val Ile Val
                 245                 250                 255

 Leu Ser Val Thr Thr Glu Ser Lys Val Glu Ser Trp Phe Ser Leu
                 260                 265                 270

 Ile Met Pro Phe Ala Thr Val Ile Phe Phe Val Met Ile Leu Asp
                 275                 280                 285

 Phe Tyr Val Asp Ser Ile Cys Ser Val Lys Met Glu Val Ser Lys
                 290                 295                 300

 Cys Ala Arg Tyr Gly Ser Phe Pro Ile Phe Ile Ser Ala Leu Leu
                 305                 310                 315

 Phe Gly Asn Phe Trp Thr His Pro Ile Thr Asp Gln Leu Arg Ala
                 320                 325                 330

 Met Asn Lys Ala Ala His Gln Glu Ser Thr Glu His Val Leu Ser
                 335                 340                 345

 Gly Gly Val Val Val Ser Ala Ile Phe Phe Ile Leu Ser Ala Asn
                 350                 355                 360

 Ile Leu Ser Ser Pro Ser Lys Arg Gly Gln Lys Gly Thr Leu Ile
                 365                 370                 375

 Gly Tyr Ser Pro Glu Gly Thr Pro Leu Tyr Asn Phe Met Gly Asp
                 380                 385                 390

 Ala Phe Gln His Ser Ser Gln Ser Ile Pro Arg Phe Ile Lys Glu
                 395                 400                 405

 Ser Leu Lys Gln Ile Leu Glu Glu Ser Asp Ser Arg Gln Ile Phe
                 410                 415                 420

 Tyr Phe Leu Cys Leu Asn Leu Leu Phe Thr Phe Val Glu Leu Phe
                 425                 430                 435

 Tyr Gly Val Leu Thr Asn Ser Leu Gly Leu Ile Ser Asp Gly Phe
                 440                 445                 450

 His Met Leu Phe Asp Cys Ser Ala Leu Val Met Gly Leu Phe Ala
                 455                 460                 465

 Ala Leu Met Ser Arg Trp Lys Ala Thr Arg Ile Phe Ser Tyr Gly
                 470                 475                 480

 Tyr Gly Arg Ile Glu Ile Leu Ser Gly Phe Ile Asn Gly Leu Phe
                 485                 490                 495

 Leu Ile Val Ile Ala Phe Phe Val Phe Met Glu Ser Val Ala Arg
                 500                 505                 510

 Leu Ile Asp Pro Pro Glu Leu Asp Thr His Met Leu Thr Pro Val
                 515                 520                 525

 Ser Val Gly Gly Leu Ile Val Asn Leu Ile Gly Ile Cys Ala Phe
                 530                 535                 540

 Ser His Ala His Ser His Ala His Gly Ala Ser Gln Gly Ser Cys
                 545                 550                 555

 His Ser Ser Asp His Ser His Ser His His Met His Gly His Ser
                 560                 565                 570

 Asp His Gly His Gly His Ser His Gly Ser Ala Gly Gly Gly Met
                 575                 580                 585

 Asn Ala Asn Met Arg Gly Val Phe Leu His Val Leu Ala Asp Thr
                 590                 595                 600

 Leu Gly Ser Ile Gly Val Ile Val Ser Thr Val Leu Ile Glu Gln
                 605                 610                 615

 Phe Gly Trp Phe Ile Ala Asp Pro Leu Cys Ser Leu Phe Ile Ala
                 620                 625                 630

 Ile Leu Ile Phe Leu Ser Val Val Pro Leu Ile Lys Asp Ala Cys
                 635                 640                 645

 Gln Val Leu Leu Leu Arg Leu Pro Pro Glu Tyr Glu Lys Glu Leu
                 650                 655                 660

 His Ile Ala Leu Glu Lys Ile Gln Lys Ile Glu Gly Leu Ile Ser
                 665                 670                 675

 Tyr Arg Asp Pro His Phe Trp Arg His Ser Ala Ser Ile Val Ala
                 680                 685                 690

 Gly Thr Ile His Ile Gln Val Thr Ser Asp Val Leu Glu Gln Arg
                 695                 700                 705

 Ile Val Gln Gln Val Thr Gly Ile Leu Lys Asp Ala Gly Val Asn
                 710                 715                 720

 Asn Leu Thr Ile Gln Val Glu Lys Glu Ala Tyr Phe Gln His Met
                 725                 730                 735

 Ser Gly Leu Ser Thr Gly Phe His Asp Val Leu Ala Met Thr Lys
                 740                 745                 750

 Gln Met Glu Ser Met Lys Tyr Cys Lys Asp Gly Thr Tyr Ile Met
                 755                 760                 765

<210> 3331
<211> 1680
<212> DNA
<213> Homo sapien

<400> 3331
 agagagctgt ttactaggca cgactgcgaa ggcaaggggg caccagctca 50

 ggactgcatc tgcctgccat ttcccttcca ctcctccttt ctggagtctg 100

 acattagaaa gccagcgaga aggaagattc aaacaaccaa ccctgatttc 150

 ctgcttctcc ttttcatgag tgttcctgtg gtctctgcac ctcctttctg 200

 tcccccggca gagggcagta gagatggccg gcccaaggcc tcggtggcgc 250

 gaccagctgc tgttcatgag catcatagtc ctcgtgattg tggtcatctg 300

 cctgatgtta tacgctcttc tctgggaggc tggcaacctc actgacctgc 350

 ccaacctgag aatcggcttc tataacttct gcctgtggaa tgaggacacc 400

 agcaccctac agtgtcacca gttccctgag ctggaagccc tgggggtgcc 450

 tcgggttggc ctgggcctgg ccaggcttgg cgtgtacggg tccctggtcc 500

 tcaccctctt tgccccccag cctctcctcc tagcccagtg caacagtgat 550

 gagagagcgt ggcggctggc agtgggcttc ctggctgtgt cctctgtgct 600

 gctggcaggc ggcctgggcc tcttcctctc ctatgtgtgg aagtgggtca 650

 ggctctccct cccggggcct gggtttctag ctctgggcag cgcccaggcc 700

 ttactcatcc tcttgcttat agccatggct gtgttccctc tgagggctga 750

 gagggctgag agcaagcttg agagctgcta aaggcttacg tgattgcaag 800

 ggttcagttc caaccatagt cagaggtggc acatctgctc agccatctca 850

 ttttacagct aacgctgatc tccagctcca gcgatggaac ccactacaga 900

 ggaggtgggg cccctgtgtc aaagaggccg aggggcagca agggcagcca 950

 gggcacctgt gacttcttag tacaagattg tctgtccttc aggacttcca 1000

 aggctcccaa agactcccta aaccatgcag ctcattgtca caccaattcc 1050

 tgctttaatt aatggatctg agcaaatctt cctctagctt caggagggtg 1100

 gggagggagt gattgccgtc atggggccag acttccaggc tgatttgcca 1150

 aatgccaaaa tgaaacctag caaagaactt acggcaacaa acgaggacat 1200

 taaaagagcg agcacctcag tgtctctggg gacatggtta aggagcttcc 1250

 actcagccca ccatagtgag tgggccgcca taagccatca ctggaactcc 1300

 aaccccagag gtccaggagt gatctctgag tgactcaaca aagacaggac 1350

 acatggggta caaagacaag gcttgactgc ttcaaagctt ccctggacct 1400

 gaagccagac agggcagagg cgtccgctga caaatcactc ccatgatgag 1450

 accctggagg actccaaatc ctcgctgtga acaggactgg acggttgcgc 1500

 acaaacaaac gctgccaccc tccacttccc aacccagaac ttggaaagac 1550

 attagcacaa cttacgcatt ggggaattgt gtgtattttc tagcacttgt 1600

 gtattggaaa acctgtatgg cagtgattta ttcatatatt cctgtccaaa 1650

 gccacactga aaacagaggc agagacatgt 1680

<210> 3332
<211> 185
<212> PRT
<213> Homo sapien

<400> 3332
 Met Ala Gly Pro Arg Pro Arg Trp Arg Asp Gln Leu Leu Phe Met
   1               5                  10                  15

 Ser Ile Ile Val Leu Val Ile Val Val Ile Cys Leu Met Leu Tyr
                  20                  25                  30

 Ala Leu Leu Trp Glu Ala Gly Asn Leu Thr Asp Leu Pro Asn Leu
                  35                  40                  45

 Arg Ile Gly Phe Tyr Asn Phe Cys Leu Trp Asn Glu Asp Thr Ser
                  50                  55                  60

 Thr Leu Gln Cys His Gln Phe Pro Glu Leu Glu Ala Leu Gly Val
                  65                  70                  75

 Pro Arg Val Gly Leu Gly Leu Ala Arg Leu Gly Val Tyr Gly Ser
                  80                  85                  90

 Leu Val Leu Thr Leu Phe Ala Pro Gln Pro Leu Leu Leu Ala Gln
                  95                 100                 105

 Cys Asn Ser Asp Glu Arg Ala Trp Arg Leu Ala Val Gly Phe Leu
                 110                 115                 120

 Ala Val Ser Ser Val Leu Leu Ala Gly Gly Leu Gly Leu Phe Leu
                 125                 130                 135

 Ser Tyr Val Trp Lys Trp Val Arg Leu Ser Leu Pro Gly Pro Gly
                 140                 145                 150

 Phe Leu Ala Leu Gly Ser Ala Gln Ala Leu Leu Ile Leu Leu Leu
                 155                 160                 165

 Ile Ala Met Ala Val Phe Pro Leu Arg Ala Glu Arg Ala Glu Ser
                 170                 175                 180

 Lys Leu Glu Ser Cys
                 185

<210> 3333
<211> 725
<212> DNA
<213> Homo sapien

<400> 3333
 gctccgggtg tcccgagagt tgtcctgcgc cggtgttccc acgtgcggcc 50

 tgaacctgag cgcataatgt tatgaggaga tgggagcact agtgattcgc 100

 ggtatcagga atttcaacct agagaaccga gcggaacggg aaatcagcaa 150

 gatgaagccc tctgtcgctc ccagacaccc ctctaccaac agcctcctgc 200

 gagagcagat tagtctctat ccagaagtta aaggagagat tgctcgtaaa 250

 gatgaaaagc tgctgtcgtt tctaaaagat gtgtatgttg attccaaaga 300

 tcctgtgtct tccttgcagg taaaagctgc tgaaacatgt caagagccga 350

 aggaattcag attgccgaaa gaccatcatt ttgatatgat aaatattaag 400

 agcattccca aaggcaaaat ttccattgta gaagcattga cacttctcaa 450

 taatcataag cttttcccag aaacctggac tgctgagaaa ataatgcaag 500

 aataccagtt agaacagaaa gatgtgaatt ctcttcttaa atattttgtt 550

 acttttgaag tcgaaatctt ccctcctgaa gacaagaaag caatacgatc 600

 aaaatgaaga aaatcacaga aatttcctat gtgtactcct catccctcct 650

 gctgtatatt ttctcatttt ttgcgtaata aattatgtta attaccaaaa 700

 aaaaaaaaaa aaaaaaaaaa aaaaa 725

<210> 3334
<211> 175
<212> PRT
<213> Homo sapien

<400> 3334
 Met Gly Ala Leu Val Ile Arg Gly Ile Arg Asn Phe Asn Leu Glu
   1               5                  10                  15

 Asn Arg Ala Glu Arg Glu Ile Ser Lys Met Lys Pro Ser Val Ala
                  20                  25                  30

 Pro Arg His Pro Ser Thr Asn Ser Leu Leu Arg Glu Gln Ile Ser
                  35                  40                  45

 Leu Tyr Pro Glu Val Lys Gly Glu Ile Ala Arg Lys Asp Glu Lys
                  50                  55                  60

 Leu Leu Ser Phe Leu Lys Asp Val Tyr Val Asp Ser Lys Asp Pro
                  65                  70                  75

 Val Ser Ser Leu Gln Val Lys Ala Ala Glu Thr Cys Gln Glu Pro
                  80                  85                  90

 Lys Glu Phe Arg Leu Pro Lys Asp His His Phe Asp Met Ile Asn
                  95                 100                 105

 Ile Lys Ser Ile Pro Lys Gly Lys Ile Ser Ile Val Glu Ala Leu
                 110                 115                 120

 Thr Leu Leu Asn Asn His Lys Leu Phe Pro Glu Thr Trp Thr Ala
                 125                 130                 135

 Glu Lys Ile Met Gln Glu Tyr Gln Leu Glu Gln Lys Asp Val Asn
                 140                 145                 150

 Ser Leu Leu Lys Tyr Phe Val Thr Phe Glu Val Glu Ile Phe Pro
                 155                 160                 165

 Pro Glu Asp Lys Lys Ala Ile Arg Ser Lys
                 170                 175

<210> 3335
<211> 760
<212> DNA
<213> Homo sapien

<400> 3335
 gagttttcat ttgtggtgag attctctccc aggccacaag acatttcctg 50

 ctcggaacct tgtttactaa tttccactgc ttttaaggcc ctgcactgaa 100

 aatgcaagct caggcgccgg tggtcgttgt gacccaacct ggagtcggtc 150

 ccggtccggc cccccagaac tccaactggc agacaggcat gtgtgactgt 200

 ttcagcgact gcggagtctg tctctgtggc acattttgtt tcccgtgcct 250

 tgggtgtcaa gttgcagctg atatgaatga atgctgtctg tgtggaacaa 300

 gcgtcgcaat gaggactctc tacaggaccc gatatggcat ccctggatct 350

 atttgtgatg actatatggc aactctttgc tgtcctcatt gtactctttg 400

 ccaaatcaag agagatatca acagaaggag agccatgcgt actttctaaa 450

 aactgatggt gaaaagctct taccgaagca acaaaattca gcagacacct 500

 cttcagcttg agttcttcac catcttttgc aactgaaata tgatggatat 550

 gcttaagtac aactgatggc atgaaaaaaa tcaaattttt gatttattat 600

 aaatgaatgt tgtccctgaa cttagctaaa tggtgcaact tagtttctcc 650

 ttgctttcat attatcgaat ttcctggctt ataaactttt taaattacat 700

 ttgaaatata aaccaaatga aatattttaa ctgataaaaa aaaaaaaaaa 750

 aaataaaaaa 760

<210> 3336
<211> 115
<212> PRT
<213> Homo sapien

<400> 3336
 Met Gln Ala Gln Ala Pro Val Val Val Val Thr Gln Pro Gly Val
   1               5                  10                  15

 Gly Pro Gly Pro Ala Pro Gln Asn Ser Asn Trp Gln Thr Gly Met
                  20                  25                  30

 Cys Asp Cys Phe Ser Asp Cys Gly Val Cys Leu Cys Gly Thr Phe
                  35                  40                  45

 Cys Phe Pro Cys Leu Gly Cys Gln Val Ala Ala Asp Met Asn Glu
                  50                  55                  60

 Cys Cys Leu Cys Gly Thr Ser Val Ala Met Arg Thr Leu Tyr Arg
                  65                  70                  75

 Thr Arg Tyr Gly Ile Pro Gly Ser Ile Cys Asp Asp Tyr Met Ala
                  80                  85                  90

 Thr Leu Cys Cys Pro His Cys Thr Leu Cys Gln Ile Lys Arg Asp
                  95                 100                 105

 Ile Asn Arg Arg Arg Ala Met Arg Thr Phe
                 110                 115

<210> 3337
<211> 2221
<212> DNA
<213> Homo sapien

<400> 3337
 gtgaccggag gcgagaaacc ccgcctcggc accctgacgc agcgcaggac 50

 ccgccccgcg cgtgacgcca gcgtcaggcc agccccggca tgctctgcgg 100

 ccgcccgcgg tccagctccg acaacaggaa ttttctccga gagcgggccg 150

 ggctcagttc agctgctgtc cagacccgga tcggcaacag tgccgcctcc 200

 agacgttctc ctgccgctcg cccgcccgtc ccagcgcccc cagccctccc 250

 gcgagggcgc cccgggacgg aaggatccac cagtctgtcg gcgcccgccg 300

 ttctcgtggt cgccgtcgcc gtcgtcgtgg tggtagtctc cgccgtcgcc 350

 tgggccatgg ccaattacat ccacgtccct cccggctccc cggaggtgcc 400

 caagctgaac gtcaccgttc aggatcagga ggagcatcgc tgccgggagg 450

 gggccctgag cctcctgcaa cacctgcggc ctcactggga cccccaggag 500

 gtgaccctgc agctcttcac agatggaatc acaaataaac ttattggctg 550

 ttacgtggga aacaccatgg aggatgtagt cctggtgaga atttatggca 600

 ataagactga gttattagtc gatcgagatg aggaagtaaa gagttttcga 650

 gtgttgcagg ctcatgggtg tgcaccacaa ctctactgta ccttcaataa 700

 tggactatgc tatgaattta tacaaggaga agcactggat ccaaagcatg 750

 tctgcaaccc agccattttc aggctaatag ctcgtcagct tgctaaaatc 800

 catgctattc atgcacacaa tggctggatc cccaaatcta atctttggct 850

 aaagatggga aagtatttct ctctcattcc cacaggattt gcagatgaag 900

 acattaataa aaggttccta agtgatatcc caagctctca gattctccag 950

 gaagagatga cttggatgaa ggagattctt tccaacctgg gctcacctgt 1000

 tgtgctttgc cataatgacc tattgtgtaa gaatataatc tacaatgaga 1050

 aacaaggtga tgtacagttc attgattatg aatattctgg atacaactac 1100

 ctggcatatg atattggaaa tcatttcaat gaatttgcag gtgtgagtga 1150

 tgtagactat agtctgtatc cagatagaga actacagagt cagtggctgc 1200

 gtgcttacct tgaagcctac aaagaattta agggctttgg gactgaagtt 1250

 actgaaaagg aggtagaaat actcttcatt caagtcaatc agtttgcatt 1300

 ggcttctcat ttcttttggg gattgtgggc tttgattcaa gccaaatact 1350

 ccactattga gtttgatttc cttgggtatg caattgttcg ttttaaccag 1400

 tactttaaaa tgaagcctga ggttactgca ttaaaagtgc ctgagtaaag 1450

 aagagattta attattctcc agtagctgag caatgcttgt gaatcttttc 1500

 ttaagaaatc ccaaaaagcc aatattagtt aaaattctgt tgtttaattt 1550

 ggttatcttg ctttataaat tatgcctcta aacaatcaaa tctatttttg 1600

 aaatagactg aatgatgtca agaaatatac ctactgctat ccgtatgtgg 1650

 tggattagaa atgtgttaaa tctgcaaaag gtataaagat gtcagtttaa 1700

 tttctttgat aatttaacct atgttgtatg tgaattattt attataaact 1750

 tagcacgatt ctgtgactgt ttttctctgt ttcacgttcg ttgagtgtaa 1800

 gcaatgaaaa tgtcccaaat aagtttttta agttttactt taataagatt 1850

 aatttcagta aacattctag ttgttcagtg taaccttttt atcttgatgc 1900

 attgtaagta aaatgaatca tttactcttg aaatgccagt cattgactga 1950

 tgtagataat ttaggatttt catataaaaa tagctgttta ggaaggtgaa 2000

 atacattcac tgtctctgtt ggtggtacat cttgttgaat tcaatattag 2050

 aaagtatttc tttttggggt aatataactt agaattaaat ccctgtttct 2100

 ctatgtagtc tggcagtata aatataaata tttaccatat aatcttggaa 2150

 taagtattag ttaatgttac caaaatctgt attaaataat gttttcaaat 2200

 gctaaaaaaa aaaaaaaaaa a 2221

<210> 3338
<211> 452
<212> PRT
<213> Homo sapien

<400> 3338
 Met Leu Cys Gly Arg Pro Arg Ser Ser Ser Asp Asn Arg Asn Phe
   1               5                  10                  15

 Leu Arg Glu Arg Ala Gly Leu Ser Ser Ala Ala Val Gln Thr Arg
                  20                  25                  30

 Ile Gly Asn Ser Ala Ala Ser Arg Arg Ser Pro Ala Ala Arg Pro
                  35                  40                  45

 Pro Val Pro Ala Pro Pro Ala Leu Pro Arg Gly Arg Pro Gly Thr
                  50                  55                  60

 Glu Gly Ser Thr Ser Leu Ser Ala Pro Ala Val Leu Val Val Ala
                  65                  70                  75

 Val Ala Val Val Val Val Val Val Ser Ala Val Ala Trp Ala Met
                  80                  85                  90

 Ala Asn Tyr Ile His Val Pro Pro Gly Ser Pro Glu Val Pro Lys
                  95                 100                 105

 Leu Asn Val Thr Val Gln Asp Gln Glu Glu His Arg Cys Arg Glu
                 110                 115                 120

 Gly Ala Leu Ser Leu Leu Gln His Leu Arg Pro His Trp Asp Pro
                 125                 130                 135

 Gln Glu Val Thr Leu Gln Leu Phe Thr Asp Gly Ile Thr Asn Lys
                 140                 145                 150

 Leu Ile Gly Cys Tyr Val Gly Asn Thr Met Glu Asp Val Val Leu
                 155                 160                 165

 Val Arg Ile Tyr Gly Asn Lys Thr Glu Leu Leu Val Asp Arg Asp
                 170                 175                 180

 Glu Glu Val Lys Ser Phe Arg Val Leu Gln Ala His Gly Cys Ala
                 185                 190                 195

 Pro Gln Leu Tyr Cys Thr Phe Asn Asn Gly Leu Cys Tyr Glu Phe
                 200                 205                 210

 Ile Gln Gly Glu Ala Leu Asp Pro Lys His Val Cys Asn Pro Ala
                 215                 220                 225

 Ile Phe Arg Leu Ile Ala Arg Gln Leu Ala Lys Ile His Ala Ile
                 230                 235                 240

 His Ala His Asn Gly Trp Ile Pro Lys Ser Asn Leu Trp Leu Lys
                 245                 250                 255

 Met Gly Lys Tyr Phe Ser Leu Ile Pro Thr Gly Phe Ala Asp Glu
                 260                 265                 270

 Asp Ile Asn Lys Arg Phe Leu Ser Asp Ile Pro Ser Ser Gln Ile
                 275                 280                 285

 Leu Gln Glu Glu Met Thr Trp Met Lys Glu Ile Leu Ser Asn Leu
                 290                 295                 300

 Gly Ser Pro Val Val Leu Cys His Asn Asp Leu Leu Cys Lys Asn
                 305                 310                 315

 Ile Ile Tyr Asn Glu Lys Gln Gly Asp Val Gln Phe Ile Asp Tyr
                 320                 325                 330

 Glu Tyr Ser Gly Tyr Asn Tyr Leu Ala Tyr Asp Ile Gly Asn His
                 335                 340                 345

 Phe Asn Glu Phe Ala Gly Val Ser Asp Val Asp Tyr Ser Leu Tyr
                 350                 355                 360

 Pro Asp Arg Glu Leu Gln Ser Gln Trp Leu Arg Ala Tyr Leu Glu
                 365                 370                 375

 Ala Tyr Lys Glu Phe Lys Gly Phe Gly Thr Glu Val Thr Glu Lys
                 380                 385                 390

 Glu Val Glu Ile Leu Phe Ile Gln Val Asn Gln Phe Ala Leu Ala
                 395                 400                 405

 Ser His Phe Phe Trp Gly Leu Trp Ala Leu Ile Gln Ala Lys Tyr
                 410                 415                 420

 Ser Thr Ile Glu Phe Asp Phe Leu Gly Tyr Ala Ile Val Arg Phe
                 425                 430                 435

 Asn Gln Tyr Phe Lys Met Lys Pro Glu Val Thr Ala Leu Lys Val
                 440                 445                 450

 Pro Glu


<210> 3339
<211> 1308
<212> DNA
<213> Homo sapien

<400> 3339
 ggaagaaaac ctgaaaaaga ccccaaagaa gaatatgaaa atggtaactg 50

 gagccgtagc gtcggtgctg gaagacgagg ccacagacac ttctgatagt 100

 gaaggaagct gtggatcgga aaaggaccac ttttattctg atgatgacgc 150

 aatagaagct gacagtgagg gtgatgctga gccctgtgac aaagaaaatg 200

 aaaatgatgg agaatcaagt gttgggacta atatgggctg ggcagatgct 250

 atggctaaag tcctcaacaa gaaaactcct gaaagtaaac ctactattct 300

 ggtcaaaaat aagaagctgg aaaaggaaaa agaaaagtta aagcaagaaa 350

 gactagagaa aataaaacag cgtgataaga ggctggagtg ggaaatgatg 400

 tgcagagtaa agccagatgt tgtccaagac aaagagacag agagaaatct 450

 tcagagaatt gcaacaaggg gtgtggtgca attatttaat gctgttcaga 500

 aacatcaaaa gaatgttgat gaaaaggtta aggaagctgg aagttctatg 550

 agaaagcgtg ctaagttgat atcaactgtt tccaagaaag atttcatcag 600

 tgttttgaga gggatggatg gaagtacaaa tgagactgct tcaagcagga 650

 agaaaccaaa agccaaacag actgaagtga aatcagaaga aggcccaggt 700

 tggacgatcc tacgtgatga tttcatgatg ggagcatcta tgaaagactg 750

 ggacaaggaa agtgatgggc cagatgacag cagaccagaa tctgcaagtg 800

 actctgatac ataaagcatc ataggaaata caattgcagt cgttttattt 850

 tttctagaaa aatatgtcat cctctgatag ttggggaatt ataaggatac 900

 catttgtaag aaagccaaaa gacttttgcc agatttcata tttccccttt 950

 tcatgtacac tttatatata cttcattaaa attatatttt aaacccttgt 1000

 ataattttaa gcattgttcc tcagaacatt tgtaaaagga tatatttctg 1050

 cttgaccagc gagatgtgca ttttgccagg atcatattgg tcatgtctat 1100

 tggtgtatta tttcagtatc accaatgttt tcagaaatac agtactaatt 1150

 catcattaaa ctctttgaag ttaatatttt tctgccttct aacttataga 1200

 ctcaactatg tatctgtagt ttttgggaat ggttggtgtt ttttgctttg 1250

 tgttgggaag ttattgagaa aacctatata ataaaattta aaattatagt 1300

 ttttcaaa 1308

<210> 3340
<211> 259
<212> PRT
<213> Homo sapien

<400> 3340
 Met Lys Met Val Thr Gly Ala Val Ala Ser Val Leu Glu Asp Glu
   1               5                  10                  15

 Ala Thr Asp Thr Ser Asp Ser Glu Gly Ser Cys Gly Ser Glu Lys
                  20                  25                  30

 Asp His Phe Tyr Ser Asp Asp Asp Ala Ile Glu Ala Asp Ser Glu
                  35                  40                  45

 Gly Asp Ala Glu Pro Cys Asp Lys Glu Asn Glu Asn Asp Gly Glu
                  50                  55                  60

 Ser Ser Val Gly Thr Asn Met Gly Trp Ala Asp Ala Met Ala Lys
                  65                  70                  75

 Val Leu Asn Lys Lys Thr Pro Glu Ser Lys Pro Thr Ile Leu Val
                  80                  85                  90

 Lys Asn Lys Lys Leu Glu Lys Glu Lys Glu Lys Leu Lys Gln Glu
                  95                 100                 105

 Arg Leu Glu Lys Ile Lys Gln Arg Asp Lys Arg Leu Glu Trp Glu
                 110                 115                 120

 Met Met Cys Arg Val Lys Pro Asp Val Val Gln Asp Lys Glu Thr
                 125                 130                 135

 Glu Arg Asn Leu Gln Arg Ile Ala Thr Arg Gly Val Val Gln Leu
                 140                 145                 150

 Phe Asn Ala Val Gln Lys His Gln Lys Asn Val Asp Glu Lys Val
                 155                 160                 165

 Lys Glu Ala Gly Ser Ser Met Arg Lys Arg Ala Lys Leu Ile Ser
                 170                 175                 180

 Thr Val Ser Lys Lys Asp Phe Ile Ser Val Leu Arg Gly Met Asp
                 185                 190                 195

 Gly Ser Thr Asn Glu Thr Ala Ser Ser Arg Lys Lys Pro Lys Ala
                 200                 205                 210

 Lys Gln Thr Glu Val Lys Ser Glu Glu Gly Pro Gly Trp Thr Ile
                 215                 220                 225

 Leu Arg Asp Asp Phe Met Met Gly Ala Ser Met Lys Asp Trp Asp
                 230                 235                 240

 Lys Glu Ser Asp Gly Pro Asp Asp Ser Arg Pro Glu Ser Ala Ser
                 245                 250                 255

 Asp Ser Asp Thr


<210> 3341
<211> 2211
<212> DNA
<213> Homo sapien

<400> 3341
 atttgggagc ggccccgaga cgcgcctggc gcggatccta aatcccgaca 50

 gctttataga gcccaggcct ggcaggctcc cagaacttga agccaccaga 100

 ccccacatgg aaccaaaggc ctcctgtcca gctgctgcac ccttgatgga 150

 gagaaaattc catgttcttg tgggtgtcac ggggagtgtc gcagccctga 200

 agttgcctct tctggtgtca aagcttttgg acattcctgg gctggaagta 250

 tcagtggtca caactgagag agccaaacat ttctacagcc cccaggacat 300

 tcctgtcacc ctctacagcg acgctgatga atgggagatg tggaagagcc 350

 gctctgaccc agttctgcac attgacctgc ggaggtgggc agacctcctg 400

 ctggtggctc ctcttgatgc caacactctg gggaaggtgg ccagtggcat 450

 ctgtgacaac ttgcttacct gcgtcatgcg ggcctgggac cgcagcaagc 500

 ccctgctctt ctgcccggcc atgaacaccg ccatgtggga gcacccgatc 550

 acagcgcagc aggtagacca gctcaaggcc tttggctatg tcgagatccc 600

 ctgtgtggcc aagaagctgg tgtgcggaga tgaaggtctc ggggccatgg 650

 ctgaagtggg gaccatcgtg gacaaagtga aagaagtcct cttccagcac 700

 agtggcttcc agcagagttg acctgggatt tctgtcatgg gtgtccctct 750

 gtactcagaa tgggttcagg ccaagtcggt gaagatggat gttggcaaaa 800

 taggaggata ccctcatttg ctgaatgggg gacctgctct gagcctgccc 850

 aggggccagg cctgctccag gttaaactgg acggaaggcc caggtctcag 900

 tttctttcaa ccaggagagg ccgctgccta gagcccctcc ccaccttttc 950

 ctggatgggt gaggcaagcc aggagagcaa gcagtgttgt cctcacggga 1000

 ggaggactga gcgactggga aaactcggct ctacatctca cccagaacgg 1050

 cttttagaaa caccacagct ggagagtcct ggctgagcct tgggagtttc 1100

 agctctttgg cggggtgccc aggtgccatg cgatcagcga agcctgcgag 1150

 ttggcaggac tctgaggttt cctgcagacc atgccatgag attgaaggtg 1200

 cggggaaata aagaaaaatc accatttagg agactccatt ctttccctac 1250

 aacccagctg tggtcccaga gatcaggggg tgttgccagg tgtggctggg 1300

 gaagggtctg ggttcacaac tcaccggcac tctttagtcc ccgtataaca 1350

 tggtggttaa ggataaagat ctgaagccag acagccccta gttccaatcc 1400

 cagctctgcc gcttactagc agtggcagtt tggttcagga cttagccttc 1450

 ctgaccttca cttacctcag ctatcttgtt atcctaccct cagggagttg 1500

 ttgagaggat tcagtgaaat tttgtgtgca gaatacccat gccactgagt 1550

 gcctggaacg tagtaaatgt caaatcaatg gaagttaaaa ctaggcatgc 1600

 atatatgcca gagagctttc ctagcattta ctgcaatgcc ctgtctcatt 1650

 ttgggaaaaa ggaaatcctg gatgctaagt tgacacatcc ctttatgcaa 1700

 gtgacaggta agcagccagg agggttgacc ctgccctggg tcccaggcct 1750

 cttgcctgct tcttggtttc ctctgttctc atcctttcag ctttgctgga 1800

 cctgaggcag gggcctgggt gtctgtgcct ccctaccccc cagtacacat 1850

 gaccaaggga agtagatcca gagacaccat gcactctggc ccagaaaccc 1900

 tctgctaccc agcttttgac ttaattgcca tttggtgtgg ctgcagcggg 1950

 gagggcttgt ctgcgtattt ggagctgagg ctgaggctgg cttcctgccc 2000

 tctggcttcc aggccaggtg tgagggacat cccatgtggg ctctgagagc 2050

 actgagagta gaggtgcctt gaggggacca ggaagcctac tggctggaat 2100

 cagtgctcca gcagcctcca cagcctttat ctcaacagca cttgacttca 2150

 ccaggtgacc ctttgggata aaattgcctt agggtatgaa ataaactata 2200

 actaaaatgg t 2211

<210> 3342
<211> 204
<212> PRT
<213> Homo sapien

<400> 3342
 Met Glu Pro Lys Ala Ser Cys Pro Ala Ala Ala Pro Leu Met Glu
   1               5                  10                  15

 Arg Lys Phe His Val Leu Val Gly Val Thr Gly Ser Val Ala Ala
                  20                  25                  30

 Leu Lys Leu Pro Leu Leu Val Ser Lys Leu Leu Asp Ile Pro Gly
                  35                  40                  45

 Leu Glu Val Ser Val Val Thr Thr Glu Arg Ala Lys His Phe Tyr
                  50                  55                  60

 Ser Pro Gln Asp Ile Pro Val Thr Leu Tyr Ser Asp Ala Asp Glu
                  65                  70                  75

 Trp Glu Met Trp Lys Ser Arg Ser Asp Pro Val Leu His Ile Asp
                  80                  85                  90

 Leu Arg Arg Trp Ala Asp Leu Leu Leu Val Ala Pro Leu Asp Ala
                  95                 100                 105

 Asn Thr Leu Gly Lys Val Ala Ser Gly Ile Cys Asp Asn Leu Leu
                 110                 115                 120

 Thr Cys Val Met Arg Ala Trp Asp Arg Ser Lys Pro Leu Leu Phe
                 125                 130                 135

 Cys Pro Ala Met Asn Thr Ala Met Trp Glu His Pro Ile Thr Ala
                 140                 145                 150

 Gln Gln Val Asp Gln Leu Lys Ala Phe Gly Tyr Val Glu Ile Pro
                 155                 160                 165

 Cys Val Ala Lys Lys Leu Val Cys Gly Asp Glu Gly Leu Gly Ala
                 170                 175                 180

 Met Ala Glu Val Gly Thr Ile Val Asp Lys Val Lys Glu Val Leu
                 185                 190                 195

 Phe Gln His Ser Gly Phe Gln Gln Ser
                 200

<210> 3343
<211> 3938
<212> DNA
<213> Homo sapien

<400> 3343
 tgagcctgtc aggctgggcg ggtccatatc cgggtggacc gggtgggtga 50

 ggctgcccct ccctccaggt cccgaggtgg ataaggggtg gggagtgacg 100

 tgcagagatt ccctttcgcc ccttcggatc caagagaggg tggcagaagg 150

 aatgcgtggg tgacttggcg tggatttagg gcgtgcccac cctgcagatc 200

 ggcctcctag agtgtcccga gggcctgaga ggccgcaggg acacgaagga 250

 agagaaggca tttcccgggg atttggagca ggcacgcgcg gcccgggcgt 300

 ccggagctgt agcagcagca gcagccgccg tgccggggcc gccaccgcgg 350

 cgggcacccg cgtcccgggc gcccacggac catggagagg gcagtccagg 400

 gcacagacgg cggcgggggt agcaacagca gcagccgcag cagcagccgt 450

 gctacctcgg cgggctcctc gccctcctgc tctctggcgg gccggggggt 500

 ctccagccgg tcggcggcgg ccgggctcgg cggcggggga agccgcagca 550

 gcccgggctc tgtggccgct agcccgtccg ggggaggcgg ccgcaggagg 600

 gagccggcgc tcgagggcgt gctcagcaaa tacaccaacc tcctccaggg 650

 ctggcagaac aggtacttcg tactggattt cgaggctggc atcctgcagt 700

 attttgtgaa tgagcaaagc aaacaccaga agcctcgagg agtcctgtct 750

 ttatctggag ccatagtgtc cctgagcgat gaagctcccc acatgctggt 800

 ggtgtactct gctaatggag agatgtttaa actgagagct gctgatgcaa 850

 aagagaaaca attctgggtg actcagcttc gagcttgtgc caaataccac 900

 atggaaatga attctaagag tgctccaagc tcccgaagcc gaagtctcac 950

 tttgctccca catggaacac ccaattctgc gtctccctgt agccagagac 1000

 acctcagtgt gggggccccc ggtgttgtca caatcacgca tcacaagtcg 1050

 cctgcagccg cccgaagagc caagagtcag tattccggcc agcttcacga 1100

 agtcagagag atgatgaacc aggtggaagg gcagcagaag aaccttgtgc 1150

 acgccattga gtccctgcca gggtccggcc ccctcactgc cttggaccag 1200

 gacctgctgc tcctgaaagc tacctctgct gccaccctca gctgccttgg 1250

 ggagtgcctc aacttgttac agcagagtgt gcaccaggcg ggccagccca 1300

 gccagaagcc aggagcctcg gaaaacatcc tgggatggca cgggtccaag 1350

 tcacattcca cagagcagct gaaaaatggg acacttggct ctttgccatc 1400

 agccagtgcc aacataacct gggcaatttt accaaactct gctgaagacg 1450

 aacaaacctc acagccagag ccagagccaa actcaggctc tgaattggtt 1500

 ttgtctgaag atgaaaaaag tgacaatgaa gataaggaag agacggaatt 1550

 gggcgtcatg gaggatcagc gtagtataat tcttcatctc atttcacaac 1600

 tcaaacttgg aatggatttg accaaggtgg tgcttcccac ctttatcctg 1650

 gagaagcgat ctttgctgga gatgtatgca gatttcatgg cgcacccaga 1700

 cctactgctg gccatcaccg ctggggccac accagaggag agagtcattt 1750

 gcttcgttga gtattatctc acagcctttc acgagggccg caagggcgct 1800

 ttagccaaga agccctacaa ccccatcata ggcgagacat ttcactgctc 1850

 ctgggaagtt cccaaggaca gggtcaagcc taagaggact gcttcccgct 1900

 ctcctgccag ctgtcacgaa cacccaatgg ccgatgaccc ttccaaaagc 1950

 tacaaactaa ggtttgtggc tgagcaagtg tcccatcacc cacccatctc 2000

 ctgcttctac tgtgagtgcg aggagaagag actgtgcgtc aacactcatg 2050

 tatggaccaa aagcaagttc atgggcatgt ccgtgggggt ctctatgata 2100

 ggggaaggtg tgttgaggct cctggaacac ggggaggagt acgtattcac 2150

 cctgcctagt gcctacgccc ggtccattct caccatcccg tgggtggagc 2200

 tcggaggaaa agtcagcatc aactgtgcca agactgggta ctcagcgaca 2250

 gtgatattcc acacgaagcc tttctatgga gggaaagtcc acagggttac 2300

 cgcagaagtg aagcacaacc caaccaacac cattgtttgt aaagcccatg 2350

 gggaatggaa tggtacttta gagttcacct acaacaatgg agaaaccaaa 2400

 gtcatcgaca caaccacact gccagtgtat cccaagaaga tcagacctct 2450

 tgagaagcag ggacccatgg agtccaggaa cctctggcgg gaggtgaccc 2500

 gatacctgcg gctgggggac attgacgcag ccaccgagca gaagcggcac 2550

 ctggaggaga agcaacgggt ggaggaacgg aagcgcgaga acctccgcac 2600

 accatggaag cccaaatatt ttatccagga gggcgatggc tgggtatact 2650

 tcaatcccct ctggaaagca cactgatggg gtggaggtgc agagctttcc 2700

 agtatagccc tgtttttgta ggaatattaa agtagtagag tatcagggtt 2750

 ttgttggcat tcactgagac cttgtattag catccaagaa atgatgagag 2800

 agagagaaat tatatactat gaaaagtgca cccccacact ctgctagagg 2850

 aatgaattta ttcaagagcc attcggggca cgtgtgtgta cacaccgtat 2900

 acgttcacac acatgcacta tgtaaacatc tgagtatgat tacacattta 2950

 aatactgcac tcaccaaggt taaagtgggt aatcataagc tcctttttat 3000

 caatgaagtt tgaagttttt ctatttttca ctttgccaaa aatgttttac 3050

 actcacaaag atattctcac ttagtcaact cctgtcaaaa tgaaggtgaa 3100

 ctggcatggc ccgatcactg tccataaggg agaaagtggc tcattcctgg 3150

 tagaagtatg ggtggttatc atttcaaaat tattgtgatt ctcacctccc 3200

 tccccacctc agtgttttgt ctgtccgcgc ccaagaaaga taagcaagta 3250

 tttcctgctg gatgggggtt ggcaggaagc tgttaaagat ttatgccaga 3300

 gccttgcagg atggagcacc tctgggacaa ctaagagcca aggcccacca 3350

 aggagttttc cacccgtctc tcatggtcac agcgctagtc attcattttt 3400

 gagaagttgc ttcttttaca tcagaaaacc agtcaatcat atggagactt 3450

 cttttgtgat gaaaaagggc tttagaagtt aaatacatgc atgcacatga 3500

 aaacatgcac aaccacagcc tcaatcttgt atttagtttg gggaaagaga 3550

 agagaatttc ctgtggatta ttttttcctc aagtgcacct ctctggttaa 3600

 cccaaactct gcaagaaagc actgtgacta aaacatacat aacgcctgca 3650

 taaatattcc atggtttcag ttaaatttca gtttttagcc tttacacatg 3700

 aggtcaaagg agtgacgaaa atacaaagca aggaaaaaat gaaatatctg 3750

 gtttttgctg aatgcttaat ttatttttta ctgtgccact ccaatattta 3800

 tcaaatccaa atagcatgaa tgcttctctg tagtaatact aattttgtgc 3850

 cttttgtctg ctttcttaag accagttgtt cacactttgt agatattaga 3900

 caaatatatt tcgattgaat acaaaaaaaa aaaaaaaa 3938

<210> 3344
<211> 764
<212> PRT
<213> Homo sapien

<400> 3344
 Met Glu Arg Ala Val Gln Gly Thr Asp Gly Gly Gly Gly Ser Asn
   1               5                  10                  15

 Ser Ser Ser Arg Ser Ser Ser Arg Ala Thr Ser Ala Gly Ser Ser
                  20                  25                  30

 Pro Ser Cys Ser Leu Ala Gly Arg Gly Val Ser Ser Arg Ser Ala
                  35                  40                  45

 Ala Ala Gly Leu Gly Gly Gly Gly Ser Arg Ser Ser Pro Gly Ser
                  50                  55                  60

 Val Ala Ala Ser Pro Ser Gly Gly Gly Gly Arg Arg Arg Glu Pro
                  65                  70                  75

 Ala Leu Glu Gly Val Leu Ser Lys Tyr Thr Asn Leu Leu Gln Gly
                  80                  85                  90

 Trp Gln Asn Arg Tyr Phe Val Leu Asp Phe Glu Ala Gly Ile Leu
                  95                 100                 105

 Gln Tyr Phe Val Asn Glu Gln Ser Lys His Gln Lys Pro Arg Gly
                 110                 115                 120

 Val Leu Ser Leu Ser Gly Ala Ile Val Ser Leu Ser Asp Glu Ala
                 125                 130                 135

 Pro His Met Leu Val Val Tyr Ser Ala Asn Gly Glu Met Phe Lys
                 140                 145                 150

 Leu Arg Ala Ala Asp Ala Lys Glu Lys Gln Phe Trp Val Thr Gln
                 155                 160                 165

 Leu Arg Ala Cys Ala Lys Tyr His Met Glu Met Asn Ser Lys Ser
                 170                 175                 180

 Ala Pro Ser Ser Arg Ser Arg Ser Leu Thr Leu Leu Pro His Gly
                 185                 190                 195

 Thr Pro Asn Ser Ala Ser Pro Cys Ser Gln Arg His Leu Ser Val
                 200                 205                 210

 Gly Ala Pro Gly Val Val Thr Ile Thr His His Lys Ser Pro Ala
                 215                 220                 225

 Ala Ala Arg Arg Ala Lys Ser Gln Tyr Ser Gly Gln Leu His Glu
                 230                 235                 240

 Val Arg Glu Met Met Asn Gln Val Glu Gly Gln Gln Lys Asn Leu
                 245                 250                 255

 Val His Ala Ile Glu Ser Leu Pro Gly Ser Gly Pro Leu Thr Ala
                 260                 265                 270

 Leu Asp Gln Asp Leu Leu Leu Leu Lys Ala Thr Ser Ala Ala Thr
                 275                 280                 285

 Leu Ser Cys Leu Gly Glu Cys Leu Asn Leu Leu Gln Gln Ser Val
                 290                 295                 300

 His Gln Ala Gly Gln Pro Ser Gln Lys Pro Gly Ala Ser Glu Asn
                 305                 310                 315

 Ile Leu Gly Trp His Gly Ser Lys Ser His Ser Thr Glu Gln Leu
                 320                 325                 330

 Lys Asn Gly Thr Leu Gly Ser Leu Pro Ser Ala Ser Ala Asn Ile
                 335                 340                 345

 Thr Trp Ala Ile Leu Pro Asn Ser Ala Glu Asp Glu Gln Thr Ser
                 350                 355                 360

 Gln Pro Glu Pro Glu Pro Asn Ser Gly Ser Glu Leu Val Leu Ser
                 365                 370                 375

 Glu Asp Glu Lys Ser Asp Asn Glu Asp Lys Glu Glu Thr Glu Leu
                 380                 385                 390

 Gly Val Met Glu Asp Gln Arg Ser Ile Ile Leu His Leu Ile Ser
                 395                 400                 405

 Gln Leu Lys Leu Gly Met Asp Leu Thr Lys Val Val Leu Pro Thr
                 410                 415                 420

 Phe Ile Leu Glu Lys Arg Ser Leu Leu Glu Met Tyr Ala Asp Phe
                 425                 430                 435

 Met Ala His Pro Asp Leu Leu Leu Ala Ile Thr Ala Gly Ala Thr
                 440                 445                 450

 Pro Glu Glu Arg Val Ile Cys Phe Val Glu Tyr Tyr Leu Thr Ala
                 455                 460                 465

 Phe His Glu Gly Arg Lys Gly Ala Leu Ala Lys Lys Pro Tyr Asn
                 470                 475                 480

 Pro Ile Ile Gly Glu Thr Phe His Cys Ser Trp Glu Val Pro Lys
                 485                 490                 495

 Asp Arg Val Lys Pro Lys Arg Thr Ala Ser Arg Ser Pro Ala Ser
                 500                 505                 510

 Cys His Glu His Pro Met Ala Asp Asp Pro Ser Lys Ser Tyr Lys
                 515                 520                 525

 Leu Arg Phe Val Ala Glu Gln Val Ser His His Pro Pro Ile Ser
                 530                 535                 540

 Cys Phe Tyr Cys Glu Cys Glu Glu Lys Arg Leu Cys Val Asn Thr
                 545                 550                 555

 His Val Trp Thr Lys Ser Lys Phe Met Gly Met Ser Val Gly Val
                 560                 565                 570

 Ser Met Ile Gly Glu Gly Val Leu Arg Leu Leu Glu His Gly Glu
                 575                 580                 585

 Glu Tyr Val Phe Thr Leu Pro Ser Ala Tyr Ala Arg Ser Ile Leu
                 590                 595                 600

 Thr Ile Pro Trp Val Glu Leu Gly Gly Lys Val Ser Ile Asn Cys
                 605                 610                 615

 Ala Lys Thr Gly Tyr Ser Ala Thr Val Ile Phe His Thr Lys Pro
                 620                 625                 630

 Phe Tyr Gly Gly Lys Val His Arg Val Thr Ala Glu Val Lys His
                 635                 640                 645

 Asn Pro Thr Asn Thr Ile Val Cys Lys Ala His Gly Glu Trp Asn
                 650                 655                 660

 Gly Thr Leu Glu Phe Thr Tyr Asn Asn Gly Glu Thr Lys Val Ile
                 665                 670                 675

 Asp Thr Thr Thr Leu Pro Val Tyr Pro Lys Lys Ile Arg Pro Leu
                 680                 685                 690

 Glu Lys Gln Gly Pro Met Glu Ser Arg Asn Leu Trp Arg Glu Val
                 695                 700                 705

 Thr Arg Tyr Leu Arg Leu Gly Asp Ile Asp Ala Ala Thr Glu Gln
                 710                 715                 720

 Lys Arg His Leu Glu Glu Lys Gln Arg Val Glu Glu Arg Lys Arg
                 725                 730                 735

 Glu Asn Leu Arg Thr Pro Trp Lys Pro Lys Tyr Phe Ile Gln Glu
                 740                 745                 750

 Gly Asp Gly Trp Val Tyr Phe Asn Pro Leu Trp Lys Ala His
                 755                 760

<210> 3345
<211> 1361
<212> DNA
<213> Homo sapien

<400> 3345
 ggggaggtag cccgcagtgc aggggcagcg cggcgcgggg ccaccgacgg 50

 gacgcggctc cgggaacatg gctcgcttcg ctctgactgt tgtccggcat 100

 ggagaaacaa gatttaacaa ggagaaaata atccaaggac aaggagtaga 150

 tgaacctctt tcagaaactg gatttaaaca agcagcagct gctggtatat 200

 ttctgaataa tgtgaagttt actcatgctt tctccagtga tctcatgagg 250

 acaaagcaga ccatgcatgg aattttggag agaagcaaat tttgcaaaga 300

 tatgacggta aagtatgact caagacttcg ggaaaggaaa tacggggttg 350

 tagaaggcaa agcgctaagt gagctgaggg ccatggccaa agcagccagg 400

 gaagagtgcc ctgtgtttac accgcccgga ggagagacgc tggaccaggt 450

 gaaaatgcgt ggaatagact tttttgaatt tctttgtcaa ctaatcctga 500

 aagaagcgga tcaaaaagaa cagttttccc aaggatctcc aagcaactgt 550

 ctggaaactt ctttggcaga gatatttcct ttaggaaaaa atcacagctc 600

 taaagttaat tcagacagcg gtattccagg attagcagcc agtgtcttag 650

 ttgtgagtca cggtgcttac atgagaagtc tgtttgatta ttttctgact 700

 gaccttaagt gttccttacc agccactctg agcagatctg aacttatgtc 750

 agtcactccc aatacaggga tgagtctctt tatcataaac tttgaggaag 800

 gaagagaagt taaaccaacg gttcagtgta tttgtatgaa cctacaggat 850

 catctaaatg gactgactga aactcgctaa ggttaaatct gcatcaaaat 900

 ctaaccaatt tgagcctctg aagggagtgc cattggcttt atttacttct 950

 ctcctctgct agtcctgatt tggaaacagt taaaagccaa tttttagctc 1000

 cagtggaacc atagccacat aaaactttaa tggacaacca tatagaatta 1050

 acttattttg tccaagtaca gttggcattt tccagaataa ttttaccacc 1100

 ctgctagatg tcatctctgg attgcacatg gatgatgaag gaactcagca 1150

 ttgaaagttg ggggattagt aaccttgtta caacggtttc tttttcattt 1200

 tagcctattt taatggctat tggtaagata ctgtatgttt ttagtatctc 1250

 atccagtgct tagaagaaag aatggtttat aattcccagt acatgtttat 1300

 attgactgtg ttatattttt aaatccttta aataaaaaat ccttataagt 1350

 ttatgtaaag c 1361

<210> 3346
<211> 270
<212> PRT
<213> Homo sapien

<400> 3346
 Met Ala Arg Phe Ala Leu Thr Val Val Arg His Gly Glu Thr Arg
   1               5                  10                  15

 Phe Asn Lys Glu Lys Ile Ile Gln Gly Gln Gly Val Asp Glu Pro
                  20                  25                  30

 Leu Ser Glu Thr Gly Phe Lys Gln Ala Ala Ala Ala Gly Ile Phe
                  35                  40                  45

 Leu Asn Asn Val Lys Phe Thr His Ala Phe Ser Ser Asp Leu Met
                  50                  55                  60

 Arg Thr Lys Gln Thr Met His Gly Ile Leu Glu Arg Ser Lys Phe
                  65                  70                  75

 Cys Lys Asp Met Thr Val Lys Tyr Asp Ser Arg Leu Arg Glu Arg
                  80                  85                  90

 Lys Tyr Gly Val Val Glu Gly Lys Ala Leu Ser Glu Leu Arg Ala
                  95                 100                 105

 Met Ala Lys Ala Ala Arg Glu Glu Cys Pro Val Phe Thr Pro Pro
                 110                 115                 120

 Gly Gly Glu Thr Leu Asp Gln Val Lys Met Arg Gly Ile Asp Phe
                 125                 130                 135

 Phe Glu Phe Leu Cys Gln Leu Ile Leu Lys Glu Ala Asp Gln Lys
                 140                 145                 150

 Glu Gln Phe Ser Gln Gly Ser Pro Ser Asn Cys Leu Glu Thr Ser
                 155                 160                 165

 Leu Ala Glu Ile Phe Pro Leu Gly Lys Asn His Ser Ser Lys Val
                 170                 175                 180

 Asn Ser Asp Ser Gly Ile Pro Gly Leu Ala Ala Ser Val Leu Val
                 185                 190                 195

 Val Ser His Gly Ala Tyr Met Arg Ser Leu Phe Asp Tyr Phe Leu
                 200                 205                 210

 Thr Asp Leu Lys Cys Ser Leu Pro Ala Thr Leu Ser Arg Ser Glu
                 215                 220                 225

 Leu Met Ser Val Thr Pro Asn Thr Gly Met Ser Leu Phe Ile Ile
                 230                 235                 240

 Asn Phe Glu Glu Gly Arg Glu Val Lys Pro Thr Val Gln Cys Ile
                 245                 250                 255

 Cys Met Asn Leu Gln Asp His Leu Asn Gly Leu Thr Glu Thr Arg
                 260                 265                 270

<210> 3347
<211> 1460
<212> DNA
<213> Homo sapien

<400> 3347
 ggcacgaggc agccaactgc tcctgcgccg ggcggggtcg tcgccgccag 50

 cggctccgag cgccggaagg gccaggtcgc agggctcctg gagctgcagg 100

 cggcgggagg ggctacaaat gcttgactca gtgatgcaga acctttcaga 150

 gttagctgga agccacagcc ctgcctcttg atgcagcctg gatccagccg 200

 gtgtgaagag gagacccctt ccctcttgtg gggtttggat cctgtgtttc 250

 tagcctttgc aaaactctac atcagggata tcctggacat gaaggagtcc 300

 cgccaggtgc caggtgtatt tttgtacaat ggacatccaa taaaacaggt 350

 agatgtcttg ggaactgtca ttggagtgag agaaagagat gctttctaca 400

 gttatggagt ggatgacagc actggagtta taaactgcat ctgctggaaa 450

 aagttgaata ctgagtctgt atcagctgct cctagtgcag caagagagct 500

 cagcttaacc tcacaactta agaagctaca agagaccatt gagcagaaaa 550

 caaagataga gatcggggac acgatccgag tcagaggcag tatccgcaca 600

 tacagagaag agcgagagat tcatgccacc gcttactata aagtggacga 650

 cccagtgtgg aacattcaaa ttgcaaggat gcttgagctg cccactatct 700

 acaggaaagt ttatgaccag ccttttcaca gctcagccct agagaaagaa 750

 gaggcactaa gcaatccagg cgccctggac ctccccagtc tcacgagttt 800

 gctgagtgaa aaagccaaag aattcctcat ggagaacaga gtgcagagct 850

 tttaccagca ggagctggaa atggtggagt ctttgctgtc ccttgccaat 900

 cagcctgtga ttcacagtgc ctgctccgac caagtgaatt ttaagaagga 950

 caccacttcc aaggcaattc atagtatatt taagaatgct atacaactgc 1000

 tgcaggaaaa aggacttgtt ttccagaaag atgatggttt tgataaccta 1050

 tactatgtaa ccagagaaga caaagacctg cacagaaaga tccaccggat 1100

 cattcagcag gactgccaga aaccaaatca catggagaag ggctgtcact 1150

 tcctgcacat cttggcctgt gctcgcctga gcatccgccc gggcctgagc 1200

 gaggctgtgc tgcagcaagt tctggagctc ctggaggacc agagtgacat 1250

 tgtcagcaca atggagcact actacacagc gttctgagca gagacacgca 1300

 gaccagctga ggaggacaaa gataaggtgg cattcacccc caggctctga 1350

 ctttcagcat catgcagggg cttatctgtc tggaggcagt tacctcataa 1400

 taaactataa aatatagtca tcttgggaaa aaaaaaaaaa aaaaaaaaaa 1450

 aaaaaaaaaa 1460

<210> 3348
<211> 368
<212> PRT
<213> Homo sapien

<400> 3348
 Met Gln Pro Gly Ser Ser Arg Cys Glu Glu Glu Thr Pro Ser Leu
   1               5                  10                  15

 Leu Trp Gly Leu Asp Pro Val Phe Leu Ala Phe Ala Lys Leu Tyr
                  20                  25                  30

 Ile Arg Asp Ile Leu Asp Met Lys Glu Ser Arg Gln Val Pro Gly
                  35                  40                  45

 Val Phe Leu Tyr Asn Gly His Pro Ile Lys Gln Val Asp Val Leu
                  50                  55                  60

 Gly Thr Val Ile Gly Val Arg Glu Arg Asp Ala Phe Tyr Ser Tyr
                  65                  70                  75

 Gly Val Asp Asp Ser Thr Gly Val Ile Asn Cys Ile Cys Trp Lys
                  80                  85                  90

 Lys Leu Asn Thr Glu Ser Val Ser Ala Ala Pro Ser Ala Ala Arg
                  95                 100                 105

 Glu Leu Ser Leu Thr Ser Gln Leu Lys Lys Leu Gln Glu Thr Ile
                 110                 115                 120

 Glu Gln Lys Thr Lys Ile Glu Ile Gly Asp Thr Ile Arg Val Arg
                 125                 130                 135

 Gly Ser Ile Arg Thr Tyr Arg Glu Glu Arg Glu Ile His Ala Thr
                 140                 145                 150

 Ala Tyr Tyr Lys Val Asp Asp Pro Val Trp Asn Ile Gln Ile Ala
                 155                 160                 165

 Arg Met Leu Glu Leu Pro Thr Ile Tyr Arg Lys Val Tyr Asp Gln
                 170                 175                 180

 Pro Phe His Ser Ser Ala Leu Glu Lys Glu Glu Ala Leu Ser Asn
                 185                 190                 195

 Pro Gly Ala Leu Asp Leu Pro Ser Leu Thr Ser Leu Leu Ser Glu
                 200                 205                 210

 Lys Ala Lys Glu Phe Leu Met Glu Asn Arg Val Gln Ser Phe Tyr
                 215                 220                 225

 Gln Gln Glu Leu Glu Met Val Glu Ser Leu Leu Ser Leu Ala Asn
                 230                 235                 240

 Gln Pro Val Ile His Ser Ala Cys Ser Asp Gln Val Asn Phe Lys
                 245                 250                 255

 Lys Asp Thr Thr Ser Lys Ala Ile His Ser Ile Phe Lys Asn Ala
                 260                 265                 270

 Ile Gln Leu Leu Gln Glu Lys Gly Leu Val Phe Gln Lys Asp Asp
                 275                 280                 285

 Gly Phe Asp Asn Leu Tyr Tyr Val Thr Arg Glu Asp Lys Asp Leu
                 290                 295                 300

 His Arg Lys Ile His Arg Ile Ile Gln Gln Asp Cys Gln Lys Pro
                 305                 310                 315

 Asn His Met Glu Lys Gly Cys His Phe Leu His Ile Leu Ala Cys
                 320                 325                 330

 Ala Arg Leu Ser Ile Arg Pro Gly Leu Ser Glu Ala Val Leu Gln
                 335                 340                 345

 Gln Val Leu Glu Leu Leu Glu Asp Gln Ser Asp Ile Val Ser Thr
                 350                 355                 360

 Met Glu His Tyr Tyr Thr Ala Phe
                 365

<210> 3349
<211> 1021
<212> DNA
<213> Homo sapien

<400> 3349
 ccgctgttat acgtcacttc cacggctcag cgtcagggag gagagagaat 50

 gtcttttcga ggcggaggtc gtggaggctt taatcgaggt ggtggaggtg 100

 gcggcttcaa ccgaggcggc agcagcaacc acttccgagg tggaggcggc 150

 ggtggaggcg gcggcaattt cagaggcggc ggcaggggag gatttggacg 200

 agggggtggc cgcggaggct ttaacaaagg ccaagaccaa ggacctccag 250

 aacgtgtagt cttattagga gagttcctgc atccctgtga agatgacata 300

 gtttgtaaat gtaccacaga tgaaaataag gtgccttatt tcaatgctcc 350

 tgtttactta gaaaacaaag aacaaattgg aaaagtggat gaaatatttg 400

 gacaactcag agatttttat ttttcagtta agttgtcaga aaacatgaag 450

 gcttcatcct ttaaaaaact acagaagttt tatatagacc catataagct 500

 gctgccactg cagaggtttt tacctcgacc tccaggtgag aaaggacctc 550

 caagaggtgg tggcagggga ggccgaggag gaggaagagg aggaggtggc 600

 agaggtggtg gcagaggcgg tggttttaga ggtggaagag gaggtggagg 650

 tgggggcttc agaggaggaa gaggtggtgg tttcagaggg agaggacatt 700

 aagtgaaaca gttgacagac atcaccagtt gacttctgca ttaacctgca 750

 tgatctgttt ctactatgga ttggaaactt gtttcttgaa caagtcttga 800

 agatcttggt cattttatga caatggatct aaaatgtcag catcatgcaa 850

 agtgcaacgg aatagtgaat tttgctctaa aagagcatga acaagtcttt 900

 ctaatgtttt gtacagtgcc tggcactctg tgggtgctca ataaatggat 950

 aggagttttc atttgaagca tatttgaatt tttaaaataa agtgttttat 1000

 tcccttaaaa aaaaaaaaaa a 1021

<210> 3350
<211> 217
<212> PRT
<213> Homo sapien

<400> 3350
 Met Ser Phe Arg Gly Gly Gly Arg Gly Gly Phe Asn Arg Gly Gly
   1               5                  10                  15

 Gly Gly Gly Gly Phe Asn Arg Gly Gly Ser Ser Asn His Phe Arg
                  20                  25                  30

 Gly Gly Gly Gly Gly Gly Gly Gly Gly Asn Phe Arg Gly Gly Gly
                  35                  40                  45

 Arg Gly Gly Phe Gly Arg Gly Gly Gly Arg Gly Gly Phe Asn Lys
                  50                  55                  60

 Gly Gln Asp Gln Gly Pro Pro Glu Arg Val Val Leu Leu Gly Glu
                  65                  70                  75

 Phe Leu His Pro Cys Glu Asp Asp Ile Val Cys Lys Cys Thr Thr
                  80                  85                  90

 Asp Glu Asn Lys Val Pro Tyr Phe Asn Ala Pro Val Tyr Leu Glu
                  95                 100                 105

 Asn Lys Glu Gln Ile Gly Lys Val Asp Glu Ile Phe Gly Gln Leu
                 110                 115                 120

 Arg Asp Phe Tyr Phe Ser Val Lys Leu Ser Glu Asn Met Lys Ala
                 125                 130                 135

 Ser Ser Phe Lys Lys Leu Gln Lys Phe Tyr Ile Asp Pro Tyr Lys
                 140                 145                 150

 Leu Leu Pro Leu Gln Arg Phe Leu Pro Arg Pro Pro Gly Glu Lys
                 155                 160                 165

 Gly Pro Pro Arg Gly Gly Gly Arg Gly Gly Arg Gly Gly Gly Arg
                 170                 175                 180

 Gly Gly Gly Gly Arg Gly Gly Gly Arg Gly Gly Gly Phe Arg Gly
                 185                 190                 195

 Gly Arg Gly Gly Gly Gly Gly Gly Phe Arg Gly Gly Arg Gly Gly
                 200                 205                 210

 Gly Phe Arg Gly Arg Gly His
                 215

<210> 3351
<211> 727
<212> DNA
<213> Homo sapien

<400> 3351
 gaacgagggt cctagctgcc gccacccgaa cagcctgtcc tggtgccccg 50

 gctccctgcc ccgcgcccag tcatgaccct gcgcccctca ctcctcccgc 100

 tccatctgct gctgctgctg ctgctcagtg cggcggtgtg ccgggctgag 150

 gctgggctcg aaaccgaaag tcccgtccgg accctccaag tggagaccct 200

 ggtggagccc ccagaaccat gtgccgagcc cgctgctttt ggagacacgc 250

 ttcacataca ctacacggga agcttggtag atggacgtat tattgacacc 300

 tccctgacca gagaccctct ggttatagaa cttggccaaa agcaggtgat 350

 tccaggtctg gagcagagtc ttctcgacat gtgtgtggga gagaagcgaa 400

 gggcaatcat tccttctcac ttggcctatg gaaaacgggg atttccacca 450

 tctgtcccag cggatgcagt ggtgcagtat gacgtggagc tgattgcact 500

 aatccgagcc aactactggc taaagctggt gaagggcatt ttgcctctgg 550

 tagggatggc catggtgcca gccctcctgg gcctcattgg gtatcaccta 600

 tacagaaagg ccaatagacc caaagtctcc aaaaagaagc tcaaggaaga 650

 gaaacgaaac aagagcaaaa agaaataata aataataaat tttaaaaaac 700

 ttaaaaaaaa aaaaaaaaaa aaaaaaa 727

<210> 3352
<211> 201
<212> PRT
<213> Homo sapien

<400> 3352
 Met Thr Leu Arg Pro Ser Leu Leu Pro Leu His Leu Leu Leu Leu
   1               5                  10                  15

 Leu Leu Leu Ser Ala Ala Val Cys Arg Ala Glu Ala Gly Leu Glu
                  20                  25                  30

 Thr Glu Ser Pro Val Arg Thr Leu Gln Val Glu Thr Leu Val Glu
                  35                  40                  45

 Pro Pro Glu Pro Cys Ala Glu Pro Ala Ala Phe Gly Asp Thr Leu
                  50                  55                  60

 His Ile His Tyr Thr Gly Ser Leu Val Asp Gly Arg Ile Ile Asp
                  65                  70                  75

 Thr Ser Leu Thr Arg Asp Pro Leu Val Ile Glu Leu Gly Gln Lys
                  80                  85                  90

 Gln Val Ile Pro Gly Leu Glu Gln Ser Leu Leu Asp Met Cys Val
                  95                 100                 105

 Gly Glu Lys Arg Arg Ala Ile Ile Pro Ser His Leu Ala Tyr Gly
                 110                 115                 120

 Lys Arg Gly Phe Pro Pro Ser Val Pro Ala Asp Ala Val Val Gln
                 125                 130                 135

 Tyr Asp Val Glu Leu Ile Ala Leu Ile Arg Ala Asn Tyr Trp Leu
                 140                 145                 150

 Lys Leu Val Lys Gly Ile Leu Pro Leu Val Gly Met Ala Met Val
                 155                 160                 165

 Pro Ala Leu Leu Gly Leu Ile Gly Tyr His Leu Tyr Arg Lys Ala
                 170                 175                 180

 Asn Arg Pro Lys Val Ser Lys Lys Lys Leu Lys Glu Glu Lys Arg
                 185                 190                 195

 Asn Lys Ser Lys Lys Lys
                 200

<210> 3353
<211> 1899
<212> DNA
<213> Homo sapien

<400> 3353
 agcgcgcgac tttttgaaag ccaggagggt tcgaattgca acggcagctg 50

 ccgggcgtat gtgttggtgc tagaggcagc tgcagggtct cgctgggggc 100

 cgctcgggac caattttgaa gaggtacttg gccacgactt attttcacct 150

 ccgacctttc cttccaggcg gtgagactct ggactgagag tggctttcac 200

 aatggaaggg atcagtaatt tcaagacacc aagcaaatta tcagaaaaaa 250

 agaaatctgt attatgttca actccaacta taaatatccc ggcctctccg 300

 tttatgcaga agcttggctt tggtactggg gtaaatgtgt acctaatgaa 350

 aagatctcca agaggtttgt ctcattctcc ttgggctgta aaaaagatta 400

 atcctatatg taatgatcat tatcgaagtg tgtatcaaaa gagactaatg 450

 gatgaagcta agattttgaa aagccttcat catccaaaca ttgttggtta 500

 tcgtgctttt actgaagcca atgatggcag tctgtgtctt gctatggaat 550

 atggaggtga aaagtctcta aatgacttaa tagaagaacg atataaagcc 600

 agccaagatc cttttccagc agccataatt ttaaaagttg ctttgaatat 650

 ggcaagaggg ttaaagtatc tgcaccaaga aaagaaactg cttcatggag 700

 acataaagtc ttcaaatgtt gtaattaaag gcgattttga aacaattaaa 750

 atctgtgatg taggagtctc tctaccactg gatgaaaata tgactgtgac 800

 tgaccctgag gcttgttaca ttggcacaga gccatggaaa cccaaagaag 850

 ctgtggagga gaatggtgtt attactgaca aggcagacat atttgccttt 900

 ggccttactt tgtgggaaat gatgacttta tcgattccac acattaatct 950

 ttcaaatgat gatgatgatg aagataaaac ttttgatgaa agtgattttg 1000

 atgatgaagc atactatgca gcgttgggaa ctaggccacc tattaatatg 1050

 gaagaactgg atgaatcata ccagaaagta attgaactct tctctgtatg 1100

 cactaatgaa gaccctaaag atcgtccttc tgctgcacac attgttgaag 1150

 ctctggaaac agatgtctag tgatcatctc agctgaagtg tggcttgcgt 1200

 aaataactgt ttattccaaa atatttacat agttactatc agtagttatt 1250

 agactctaaa attggcatat ttgaggacca tagtttcttg ttaacatatg 1300

 gataactatt tctaatatga aatatgctta tattggctat aagcacttgg 1350

 aattgtactg ggttttctgt aaagttttag aaactagcta cataagtact 1400

 ttgatactgc tcatgctgac ttaaaacact agcagtaaaa cgctgtaaac 1450

 tgtaacatta aattgaatga ccattacttt tattaatgat ctttcttaaa 1500

 tattctatat tttaatggat ctactgacat tagcactttg tacagtacaa 1550

 aataaagtct acatttgttt aaaacactga accttttgct gatgtgttta 1600

 tcaaatgata actggaagct gaggagaata tgcctcaaaa agagtagctc 1650

 cttggatact tcagactctg gttacagatt gtcttgatct cttggatctc 1700

 ctcagatctt tggtttttgc tttaatttat taaatgtatt ttccatactg 1750

 agtttaaaat ttattaattt gtaccttaag catttcccag ctgtgtaaaa 1800

 acaataaaac tcaaatagga tgataaagaa taaaggacac tttgggtacc 1850

 agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1899

<210> 3354
<211> 322
<212> PRT
<213> Homo sapien

<400> 3354
 Met Glu Gly Ile Ser Asn Phe Lys Thr Pro Ser Lys Leu Ser Glu
   1               5                  10                  15

 Lys Lys Lys Ser Val Leu Cys Ser Thr Pro Thr Ile Asn Ile Pro
                  20                  25                  30

 Ala Ser Pro Phe Met Gln Lys Leu Gly Phe Gly Thr Gly Val Asn
                  35                  40                  45

 Val Tyr Leu Met Lys Arg Ser Pro Arg Gly Leu Ser His Ser Pro
                  50                  55                  60

 Trp Ala Val Lys Lys Ile Asn Pro Ile Cys Asn Asp His Tyr Arg
                  65                  70                  75

 Ser Val Tyr Gln Lys Arg Leu Met Asp Glu Ala Lys Ile Leu Lys
                  80                  85                  90

 Ser Leu His His Pro Asn Ile Val Gly Tyr Arg Ala Phe Thr Glu
                  95                 100                 105

 Ala Asn Asp Gly Ser Leu Cys Leu Ala Met Glu Tyr Gly Gly Glu
                 110                 115                 120

 Lys Ser Leu Asn Asp Leu Ile Glu Glu Arg Tyr Lys Ala Ser Gln
                 125                 130                 135

 Asp Pro Phe Pro Ala Ala Ile Ile Leu Lys Val Ala Leu Asn Met
                 140                 145                 150

 Ala Arg Gly Leu Lys Tyr Leu His Gln Glu Lys Lys Leu Leu His
                 155                 160                 165

 Gly Asp Ile Lys Ser Ser Asn Val Val Ile Lys Gly Asp Phe Glu
                 170                 175                 180

 Thr Ile Lys Ile Cys Asp Val Gly Val Ser Leu Pro Leu Asp Glu
                 185                 190                 195

 Asn Met Thr Val Thr Asp Pro Glu Ala Cys Tyr Ile Gly Thr Glu
                 200                 205                 210

 Pro Trp Lys Pro Lys Glu Ala Val Glu Glu Asn Gly Val Ile Thr
                 215                 220                 225

 Asp Lys Ala Asp Ile Phe Ala Phe Gly Leu Thr Leu Trp Glu Met
                 230                 235                 240

 Met Thr Leu Ser Ile Pro His Ile Asn Leu Ser Asn Asp Asp Asp
                 245                 250                 255

 Asp Glu Asp Lys Thr Phe Asp Glu Ser Asp Phe Asp Asp Glu Ala
                 260                 265                 270

 Tyr Tyr Ala Ala Leu Gly Thr Arg Pro Pro Ile Asn Met Glu Glu
                 275                 280                 285

 Leu Asp Glu Ser Tyr Gln Lys Val Ile Glu Leu Phe Ser Val Cys
                 290                 295                 300

 Thr Asn Glu Asp Pro Lys Asp Arg Pro Ser Ala Ala His Ile Val
                 305                 310                 315

 Glu Ala Leu Glu Thr Asp Val
                 320

<210> 3355
<211> 1124
<212> DNA
<213> Homo sapien

<400> 3355
 atgctgctga aagagtaccg gatctgcatg ccgctcaccg tagacgagta 50

 caaaattgga cagctgtaca tgatcagcaa acacagccat gaacagagtg 100

 accggggaga aggggtggag gtcgtccaga atgagccctt tgaggaccct 150

 caccatggca atgggcagtt caccgagaag cgggtgtatc tcaacagcaa 200

 actgcctagt tgggctagag ctgttgtccc caaaatattt tatgtgacag 250

 agaaggcttg gaactattat ccctacacaa ttacagaata cacatgttcc 300

 tttctgccga aattctccat tcatatagaa accaagtatg aggacaacaa 350

 aggaagcaat gacaccattt tcgacagtga agccaaagac gtggagagag 400

 aagtttgctt tattgatatt gcctgcgatg aaattccaga gcgctactac 450

 aaagaatccg aggatcctaa gcacttcaag tcagagaaga caggacgggg 500

 acagttgagg gaaggctgga gagatagtca tcagcctatc atgtgctcct 550

 acaagctggt gactgtgaag tctgaggtct gggggcttca gaccagagtg 600

 gaacaatttg tacacaaggt ggtccgagac attctgctga ttggacatag 650

 acaggctttt gcatgggttg atgagtggta tgacatgaca atggatgaag 700

 tccgagaatt tgaacgagcc actcaggaag ccaccaacaa gaaaatcggc 750

 attttcccac ctgcaatttc tatctccagc atccccctgc tgccttcttc 800

 cgtccgcagt gcgccttcta gtgctccatc cacccctctc tccacagacg 850

 cacccgaatt tctgtccgtt cccaaagatc ggccccggaa aaagtctgcc 900

 ccagaaactc tcacacttcc agaccctgag aaaaaagcca ccctgaattt 950

 acccggcatg cactcttcag ataagccatg tcggcccaaa tctgagtaac 1000

 tttatataaa tatctcatgg ggttttatat tttcatttgt tgttgttgtt 1050

 tttttttaag aatcttctga tagagaaaaa gactgctttg tcactcaaac 1100

 atgttccttc gacctttcag tgtg 1124

<210> 3356
<211> 332
<212> PRT
<213> Homo sapien

<400> 3356
 Met Leu Leu Lys Glu Tyr Arg Ile Cys Met Pro Leu Thr Val Asp
   1               5                  10                  15

 Glu Tyr Lys Ile Gly Gln Leu Tyr Met Ile Ser Lys His Ser His
                  20                  25                  30

 Glu Gln Ser Asp Arg Gly Glu Gly Val Glu Val Val Gln Asn Glu
                  35                  40                  45

 Pro Phe Glu Asp Pro His His Gly Asn Gly Gln Phe Thr Glu Lys
                  50                  55                  60

 Arg Val Tyr Leu Asn Ser Lys Leu Pro Ser Trp Ala Arg Ala Val
                  65                  70                  75

 Val Pro Lys Ile Phe Tyr Val Thr Glu Lys Ala Trp Asn Tyr Tyr
                  80                  85                  90

 Pro Tyr Thr Ile Thr Glu Tyr Thr Cys Ser Phe Leu Pro Lys Phe
                  95                 100                 105

 Ser Ile His Ile Glu Thr Lys Tyr Glu Asp Asn Lys Gly Ser Asn
                 110                 115                 120

 Asp Thr Ile Phe Asp Ser Glu Ala Lys Asp Val Glu Arg Glu Val
                 125                 130                 135

 Cys Phe Ile Asp Ile Ala Cys Asp Glu Ile Pro Glu Arg Tyr Tyr
                 140                 145                 150

 Lys Glu Ser Glu Asp Pro Lys His Phe Lys Ser Glu Lys Thr Gly
                 155                 160                 165

 Arg Gly Gln Leu Arg Glu Gly Trp Arg Asp Ser His Gln Pro Ile
                 170                 175                 180

 Met Cys Ser Tyr Lys Leu Val Thr Val Lys Ser Glu Val Trp Gly
                 185                 190                 195

 Leu Gln Thr Arg Val Glu Gln Phe Val His Lys Val Val Arg Asp
                 200                 205                 210

 Ile Leu Leu Ile Gly His Arg Gln Ala Phe Ala Trp Val Asp Glu
                 215                 220                 225

 Trp Tyr Asp Met Thr Met Asp Glu Val Arg Glu Phe Glu Arg Ala
                 230                 235                 240

 Thr Gln Glu Ala Thr Asn Lys Lys Ile Gly Ile Phe Pro Pro Ala
                 245                 250                 255

 Ile Ser Ile Ser Ser Ile Pro Leu Leu Pro Ser Ser Val Arg Ser
                 260                 265                 270

 Ala Pro Ser Ser Ala Pro Ser Thr Pro Leu Ser Thr Asp Ala Pro
                 275                 280                 285

 Glu Phe Leu Ser Val Pro Lys Asp Arg Pro Arg Lys Lys Ser Ala
                 290                 295                 300

 Pro Glu Thr Leu Thr Leu Pro Asp Pro Glu Lys Lys Ala Thr Leu
                 305                 310                 315

 Asn Leu Pro Gly Met His Ser Ser Asp Lys Pro Cys Arg Pro Lys
                 320                 325                 330

 Ser Glu


<210> 3357
<211> 5566
<212> DNA
<213> Homo sapien

<400> 3357
 atttttggct gcctctgtcg gtctgttcag ttaccacgtg aaccgccgac 50

 ggagacccgt agtgggggag gcggcggcag cgttaagtga gaaaggaaaa 100

 aagacaacga ggaaaaagga ggtgtccggg tagggcaacg cggcgacacc 150

 cgaggcctgg tggtggcggc ggatcgagat attcaaggct gaagcagcta 200

 cggaacggca gcggcggcgg tcggacaaac tgactgaccg agccgggtgg 250

 tggcgggagc agcgggagca gccggaacga tgccggccgt gagcctcccg 300

 cccaaggaga atgcgctctt caagcggatc ttgaggtgtt atgaacataa 350

 acagtataga aatggattga aattctgtaa acaaatactt tctaatccca 400

 aatttgcaga gcatggagaa accttggcta tgaaaggatt aacattgaac 450

 tgtttgggga aaaaggaaga agcttatgaa ttggttcgta gaggtttgag 500

 aaatgacttg aagagtcatg tgtgttggca cgtttatggc cttcttcaga 550

 ggtcagacaa gaagtatgat gaagccatta agtgttacag aaatgcacta 600

 aaatgggata aagacaatct tcaaatctta agggaccttt ccttactaca 650

 gattcaaatg cgagatcttg agggttacag ggaaacgagg tatcagttac 700

 ttcagcttcg acctgcgcag agagcatcat ggattggtta tgctattgct 750

 taccatttat tagaagatta tgaaatggca gcaaagattt tagaagaatt 800

 taggaaaaca caacagacat cccctgacaa ggtggattat gaatatagtg 850

 aactactctt atatcagaat caagttcttc gggaagcagg tctctataga 900

 gaagctttgg aacatctttg tacctatgaa aagcagattt gtgataaact 950

 tgctgtagaa gaaaccaaag gggaacttct gttgcaacta tgtcgtttgg 1000

 aagatgctgc agatgtttat agaggattgc aagagagaaa tcctgaaaac 1050

 tgggcctatt acaaaggctt ggaaaaagca ctcaagccag ctaatatgtt 1100

 agaacggcta aaaatttatg aggaagcctg gactaaatat cccaggggac 1150

 tggtgccaag aaggctgccg ttaaactttt tatctggtga gaagtttaaa 1200

 gaatgtttgg ataagttcct aaggatgaat ttcagcaagg gttgcccacc 1250

 agtcttcaat actttaagat cattatacaa agacaaagaa aaggtggcaa 1300

 tcatagaaga gttagtagta ggttatgaaa cctctctaaa aagctgccgg 1350

 ttatttaacc ccaatgatga tggaaaggag gaaccaccaa ccacattact 1400

 ttgggtccag tactacttgg cacaacatta tgacaaaatt ggtcagccat 1450

 ctattgcttt ggagtacata aatactgcta ttgaaagtac acctacatta 1500

 atagaactct ttctcgtgaa agctaaaatc tataagcatg ctggaaatat 1550

 taaagaagct gcaaggtgga tggatgaggc ccaggccttg gacacagcag 1600

 acagatttat caactccaaa tgtgcaaaat acatgctaaa agccaacctg 1650

 attaaagaag ctgaagaaat gtgctcaaag tttacaaggg aaggaacatc 1700

 agcggtagag aatttgaatg aaatgcagtg catgtggttc caaacagaat 1750

 gtgcccaggc ttataaagca atgaataaat ttggtgaagc acttaagaaa 1800

 tgtcatgaga ttgagagaaa atcactgatg accagtttga ctttcataca 1850

 tactgtatga ggaagattac ccttagatca tatgtggact tattaaaact 1900

 agaagatgta cttcgacagc atccatttta cttcaaggca gcaagaattg 1950

 ctatagagat ctatttgaag cttcatgaca acccccttac agatgagaat 2000

 aaagaacacg aagctgatac agcaaacatg tctgacaaag agctaaagaa 2050

 gctacgtaat aaacaaagaa gagctcaaaa gaaagcccag atagaagaag 2100

 agaaaaaaaa tgcagaaaaa gaaaagcagc agagaaatca gaaaaagaag 2150

 aaggatgatg atgatgagga gataggaggt ccaaaagaag aacttattcc 2200

 agagaaactg gccaaggttg aaactccatt ggaagaagct attaaatttt 2250

 taacaccgtt gaagaacttg gtgaagaaca agatagagac tcatcttttt 2300

 gcctttgaga tttactttag gaaagaaaag tttcttttga tgctacaatc 2350

 agtaaagagg gcatttgcta ttgattctag tcatccctgg cttcatgagt 2400

 gtatgattcg tctctttaat actgcagtgt gtgaaagtaa agatttatct 2450

 gatacagtta gaacagtatt aaaacaagaa atgaatcgtc tttttggagc 2500

 aacgaatcca aagaatttta atgaaacttt tctgaaaagg aattctgatt 2550

 cattgccaca cagattatca gctgccaaaa tggtatatta cttagatcct 2600

 tctagtcaga agcgagctat agagttggca acaacacttg atgaatctct 2650

 cactaacaga aacctccaga catgtatgga ggtattggaa gccttgtatg 2700

 atggtagcct aggagactgt aaagaagctg ctgaaattta tagagcaaat 2750

 tgtcataagc ttttccctta tgctttggct ttcatgcctc ctggatatga 2800

 agaggatatg aagatcacag ttaatggaga tagttctgca gaagctgaag 2850

 aactggccaa tgaaatttga acatcactaa acaagcaaat ggaatgactt 2900

 tggaccatat ctagtatata atatttttgt cacgcacctg ctgcattgct 2950

 ctaacttaca cagaatgaga ggagtaaatg ttcttgcctt caaatagtgt 3000

 tttacgtttt ttatcctgct gaaaaagtat atataaaata tctaacatta 3050

 caggatagag gttcagtttc ttaaaaaatt aaagctgcta aaattgagtg 3100

 gttaaaaaag ataccttatc ctattcctcc ccacccaccc atgtttttaa 3150

 actaatttat ataaaatctg gaggctgtta cagctaacaa agcaggtgtg 3200

 tggcagaaat attactttaa atttgtcttg tgagatttta ctatatctca 3250

 gacagcataa atgctgtttt agcactggat tctttcactg agcacaaaga 3300

 gttgttgggg ctttagcatc tgactgattt tgttacgggg ttgattctga 3350

 ccataggaag tatgcaatgt gaatcactat ttacagagaa acctacaaca 3400

 gatgcttgat gttgtagaaa ctgggacata tagataccaa gcaaaattat 3450

 aagaaaccta taaggtgttc aatacgcttg tgtttccaaa attcactgta 3500

 catgatcagt ttggtgttct tgtaccacag tttttaactg aaggaaccag 3550

 ttgtaacagt ctcaatttta actaaaactt gaagaactaa aacaacaatg 3600

 caaacctttc agcattgttt ggccaaactt gttaaaactg taatgcaaga 3650

 accaaatgca ctgtgatgtg gcaccaacta attagcaagc atgaattttt 3700

 cacccaagag tgaaaaaagg aaaatctacc atggcttgaa gttaaagagc 3750

 agaactcctg actaccattc tatgactgat caaaagacta atagttaaaa 3800

 acctcagcag gccttgttca cgatatgcag aaaaaaaagt gctgcagttt 3850

 agatacctct ggaatttttc cacagtgtca caggtttgta atacttgaag 3900

 ccctacattt ctaagaatat atttcttgct cagttgtttc aggcaagccc 3950

 aagactttgt aatttttaaa gggcccaaga tttttttttt tttttttttt 4000

 tcaaataaca gaccagcttc tttttcttgc agttacagat gtaatttcct 4050

 ttttgttgtc aaacataagg taccaaatat gatgcaataa attgttttga 4100

 aaaacagttg tgtgaatatt tcaactaatc tgtgttgggc ttctgtgaaa 4150

 tacacaggtg gaaacagagg tgcaagccag aggcaatgta atatgctgta 4200

 aggctagtgc agatgggagc tttttagaag gggctaagtg ctggtgtcag 4250

 ggaaattcca taatgaagta gaatgctgct cctgcattaa gatttcattg 4300

 agggcaaggc tggtggcagg tactatgaat gtaattcata atttaaaagg 4350

 aaaactaaaa actattttga tttgggaaaa tgagccttaa tttgttaaac 4400

 ctatacactg agaactagcc tcaggcttaa tattctcatt gcatttgcaa 4450

 gatctgagca aataagatta agtaaaacaa atcaattgta tatataattg 4500

 acctttttgt ggaacatgta gtttatagaa agtatactct aaagggaatt 4550

 tgccgaagac cttttactga ttgaacagtt gtgctacaat caacttttca 4600

 tagtacatga cctgcattcc acatctcagt ctaacagttt agtagtgatg 4650

 taaagagaag tacaaaccga actccagtgc tttgttatgt tttattaact 4700

 ggccctgtct caggaacatc ttaacagatg gcaaaaaaac aaaaactttt 4750

 tttcaactcc tatgagtggc aactgaagtt cttattgttg ggaaagaaca 4800

 ctagtcctac ctctgccact aatgaggtgt ttggaggagg taccagccat 4850

 ataatagggg gtgtatgtgt gaattttgtt taaactctac tgtatattga 4900

 aatgaaattc atttatttgt cttgacaatg ttcaaatgat gtagattgtc 4950

 ttagaatgaa tattcataag tactcagaac tcttaagatg cagatgccac 5000

 ccgtgaggag ctaaattcct aatgtgtatt gtattccaac ccaattttac 5050

 tggaactatt gaataaatct tttattttct ttcaggttta cttgatagtg 5100

 gatacattgg tgtcagagga ccttgactgg gttcatttta tgtccagaca 5150

 tcacccctga aacactgtac tgtactatct tgctctgagt agtatcaact 5200

 ggatcgtctc atatttgcct cattcatcct attaatttca aatgatactg 5250

 tgggggaaaa acagggttag aaaaacaagt ggaaaaaatg gagtgatgtt 5300

 gtaatctaaa caagtgcctt atgtttattg ctaagaactg gtgttaccaa 5350

 cccttttgag aagaaagggt ctcttgacct gtattaacat aggaaagtaa 5400

 agttcttttt gtttttcttt ataagctact cttgtcattt ctcgttgaaa 5450

 aactaaaatc tgactaggtt agtttactca gctttaatta gatagttgag 5500

 tcatatattt tcaacatttt tctgtatcgt atttattatg cacaaaaata 5550

 aagtgtgatc tctaat 5566

<210> 3358
<211> 526
<212> PRT
<213> Homo sapien

<400> 3358
 Met Pro Ala Val Ser Leu Pro Pro Lys Glu Asn Ala Leu Phe Lys
   1               5                  10                  15

 Arg Ile Leu Arg Cys Tyr Glu His Lys Gln Tyr Arg Asn Gly Leu
                  20                  25                  30

 Lys Phe Cys Lys Gln Ile Leu Ser Asn Pro Lys Phe Ala Glu His
                  35                  40                  45

 Gly Glu Thr Leu Ala Met Lys Gly Leu Thr Leu Asn Cys Leu Gly
                  50                  55                  60

 Lys Lys Glu Glu Ala Tyr Glu Leu Val Arg Arg Gly Leu Arg Asn
                  65                  70                  75

 Asp Leu Lys Ser His Val Cys Trp His Val Tyr Gly Leu Leu Gln
                  80                  85                  90

 Arg Ser Asp Lys Lys Tyr Asp Glu Ala Ile Lys Cys Tyr Arg Asn
                  95                 100                 105

 Ala Leu Lys Trp Asp Lys Asp Asn Leu Gln Ile Leu Arg Asp Leu
                 110                 115                 120

 Ser Leu Leu Gln Ile Gln Met Arg Asp Leu Glu Gly Tyr Arg Glu
                 125                 130                 135

 Thr Arg Tyr Gln Leu Leu Gln Leu Arg Pro Ala Gln Arg Ala Ser
                 140                 145                 150

 Trp Ile Gly Tyr Ala Ile Ala Tyr His Leu Leu Glu Asp Tyr Glu
                 155                 160                 165

 Met Ala Ala Lys Ile Leu Glu Glu Phe Arg Lys Thr Gln Gln Thr
                 170                 175                 180

 Ser Pro Asp Lys Val Asp Tyr Glu Tyr Ser Glu Leu Leu Leu Tyr
                 185                 190                 195

 Gln Asn Gln Val Leu Arg Glu Ala Gly Leu Tyr Arg Glu Ala Leu
                 200                 205                 210

 Glu His Leu Cys Thr Tyr Glu Lys Gln Ile Cys Asp Lys Leu Ala
                 215                 220                 225

 Val Glu Glu Thr Lys Gly Glu Leu Leu Leu Gln Leu Cys Arg Leu
                 230                 235                 240

 Glu Asp Ala Ala Asp Val Tyr Arg Gly Leu Gln Glu Arg Asn Pro
                 245                 250                 255

 Glu Asn Trp Ala Tyr Tyr Lys Gly Leu Glu Lys Ala Leu Lys Pro
                 260                 265                 270

 Ala Asn Met Leu Glu Arg Leu Lys Ile Tyr Glu Glu Ala Trp Thr
                 275                 280                 285

 Lys Tyr Pro Arg Gly Leu Val Pro Arg Arg Leu Pro Leu Asn Phe
                 290                 295                 300

 Leu Ser Gly Glu Lys Phe Lys Glu Cys Leu Asp Lys Phe Leu Arg
                 305                 310                 315

 Met Asn Phe Ser Lys Gly Cys Pro Pro Val Phe Asn Thr Leu Arg
                 320                 325                 330

 Ser Leu Tyr Lys Asp Lys Glu Lys Val Ala Ile Ile Glu Glu Leu
                 335                 340                 345

 Val Val Gly Tyr Glu Thr Ser Leu Lys Ser Cys Arg Leu Phe Asn
                 350                 355                 360

 Pro Asn Asp Asp Gly Lys Glu Glu Pro Pro Thr Thr Leu Leu Trp
                 365                 370                 375

 Val Gln Tyr Tyr Leu Ala Gln His Tyr Asp Lys Ile Gly Gln Pro
                 380                 385                 390

 Ser Ile Ala Leu Glu Tyr Ile Asn Thr Ala Ile Glu Ser Thr Pro
                 395                 400                 405

 Thr Leu Ile Glu Leu Phe Leu Val Lys Ala Lys Ile Tyr Lys His
                 410                 415                 420

 Ala Gly Asn Ile Lys Glu Ala Ala Arg Trp Met Asp Glu Ala Gln
                 425                 430                 435

 Ala Leu Asp Thr Ala Asp Arg Phe Ile Asn Ser Lys Cys Ala Lys
                 440                 445                 450

 Tyr Met Leu Lys Ala Asn Leu Ile Lys Glu Ala Glu Glu Met Cys
                 455                 460                 465

 Ser Lys Phe Thr Arg Glu Gly Thr Ser Ala Val Glu Asn Leu Asn
                 470                 475                 480

 Glu Met Gln Cys Met Trp Phe Gln Thr Glu Cys Ala Gln Ala Tyr
                 485                 490                 495

 Lys Ala Met Asn Lys Phe Gly Glu Ala Leu Lys Lys Cys His Glu
                 500                 505                 510

 Ile Glu Arg Lys Ser Leu Met Thr Ser Leu Thr Phe Ile His Thr
                 515                 520                 525

 Val


<210> 3359
<211> 1844
<212> DNA
<213> Homo sapien

<400> 3359
 agagtcgggt agacggcagc gggagcggtg gcgtctcccc gccttccctc 50

 cctcccgggc ctgggcgccc agccggacag gtgagcggca gccaggtgag 100

 cgcgcccacc tgcgcctctc cgcgcggccc gccctccccg gcgccgggct 150

 cctctccgcg cccctgtcgg cgcggaaccc tggcctcgtc cgcggcccag 200

 ctccctggag cctcgcatca gcgggggcgc ccccgcgagc tgcgctctcc 250

 ccggccggag cgctcctcct ccagccccca gcccgcaggg tactttgccc 300

 tcggagcgaa ggaggctcca gaactggtag agccgggcca tcgggctggg 350

 cacctccccg cggcgcccgc agcgcggagt ccactgaccg gctcaaaggt 400

 atggcgttga cggtggatgt ggccgggcca gcgccctggg gcttccgtat 450

 cacagggggc agggatttcc acacgcccat catggtgact aaggtggccg 500

 agcggggcaa agccaaggac gctgacctcc ggcctggaga cataatcgtg 550

 gccatcaacg gggaaagcgc ggagggcatg ctgcatgccg aggcccagag 600

 caagatccgc cagagcccct cgcccctgcg gctgcagctg gaccggtctc 650

 aggctacgtc tccagggcag accaatgggg acagctcctt ggaagtgctg 700

 gcgactcgct tccagggctc cgtgaggaca tacactgaga gtcagtcctc 750

 cttaaggtcc tcctactcca gcccaacctc cctcagcccg agggccggca 800

 gccccttctc accaccaccc tctagcagct ccctcactgg agaggcggcc 850

 atcagccgca gcttccagag tctggcatgt tccccgggcc tccccgctgc 900

 tgaccgcctg tcctactcag gccgccctgg aagccgacag gccggcctcg 950

 gccgcgctgg cgactcggcg gtgctggtgc tgccgccttc cccgggccct 1000

 cgttcctcca ggcccagcat ggactcggaa gggggaagcc tcctcctgga 1050

 cgaggactcg gaagtcttca agatgctgca ggaaaatcgc gagggacggg 1100

 cggccccccg acagtccagc tcctttcggc tcttgcagga agccctggag 1150

 gctgaggaga gaggtggcac gccagccttc ttgcccagct cactgagccc 1200

 ccagtcctcc ctgcccgcct ccagggccct ggccacccct cccaagctcc 1250

 acacttgtga gaagtgcagt accagcatcg cgaaccaggc tgtgcgcatc 1300

 caggagggcc ggtaccgcca ccccggctgc tacacctgtg ccgactgtgg 1350

 gctgaacctg aagatgcgcg ggcacttctg ggtgggtgac gagctgtact 1400

 gtgagaagca tgcccgccag cgctactccg cacctgccac cctcagctct 1450

 cgggcctgag cccgccatgc cctcagcctg cctcactgct gggccagggt 1500

 catgcctata taagttggca tggcagggac aatggtgggc agttgctctt 1550

 acatgagcta agtttggaga cctgaggccc ctttgtcctc gctgggtggg 1600

 ccaaggtctg ggacctgtct tggactgtgg gagactcacc ctcaccttgc 1650

 caggcctctc ccctgcagga ctggcattgc actagtctga ggtggccact 1700

 gcctttgatc aacctttgtg tgcgagggtc taagtagggt cgaacacaga 1750

 agtgggaagg agaggggtgg gccaggggct aatggtgtca ctgtgtaaag 1800

 tttttgacat actagctcta taaatatatg aatatggaca aaat 1844

<210> 3360
<211> 352
<212> PRT
<213> Homo sapien

<400> 3360
 Met Ala Leu Thr Val Asp Val Ala Gly Pro Ala Pro Trp Gly Phe
   1               5                  10                  15

 Arg Ile Thr Gly Gly Arg Asp Phe His Thr Pro Ile Met Val Thr
                  20                  25                  30

 Lys Val Ala Glu Arg Gly Lys Ala Lys Asp Ala Asp Leu Arg Pro
                  35                  40                  45

 Gly Asp Ile Ile Val Ala Ile Asn Gly Glu Ser Ala Glu Gly Met
                  50                  55                  60

 Leu His Ala Glu Ala Gln Ser Lys Ile Arg Gln Ser Pro Ser Pro
                  65                  70                  75

 Leu Arg Leu Gln Leu Asp Arg Ser Gln Ala Thr Ser Pro Gly Gln
                  80                  85                  90

 Thr Asn Gly Asp Ser Ser Leu Glu Val Leu Ala Thr Arg Phe Gln
                  95                 100                 105

 Gly Ser Val Arg Thr Tyr Thr Glu Ser Gln Ser Ser Leu Arg Ser
                 110                 115                 120

 Ser Tyr Ser Ser Pro Thr Ser Leu Ser Pro Arg Ala Gly Ser Pro
                 125                 130                 135

 Phe Ser Pro Pro Pro Ser Ser Ser Ser Leu Thr Gly Glu Ala Ala
                 140                 145                 150

 Ile Ser Arg Ser Phe Gln Ser Leu Ala Cys Ser Pro Gly Leu Pro
                 155                 160                 165

 Ala Ala Asp Arg Leu Ser Tyr Ser Gly Arg Pro Gly Ser Arg Gln
                 170                 175                 180

 Ala Gly Leu Gly Arg Ala Gly Asp Ser Ala Val Leu Val Leu Pro
                 185                 190                 195

 Pro Ser Pro Gly Pro Arg Ser Ser Arg Pro Ser Met Asp Ser Glu
                 200                 205                 210

 Gly Gly Ser Leu Leu Leu Asp Glu Asp Ser Glu Val Phe Lys Met
                 215                 220                 225

 Leu Gln Glu Asn Arg Glu Gly Arg Ala Ala Pro Arg Gln Ser Ser
                 230                 235                 240

 Ser Phe Arg Leu Leu Gln Glu Ala Leu Glu Ala Glu Glu Arg Gly
                 245                 250                 255

 Gly Thr Pro Ala Phe Leu Pro Ser Ser Leu Ser Pro Gln Ser Ser
                 260                 265                 270

 Leu Pro Ala Ser Arg Ala Leu Ala Thr Pro Pro Lys Leu His Thr
                 275                 280                 285

 Cys Glu Lys Cys Ser Thr Ser Ile Ala Asn Gln Ala Val Arg Ile
                 290                 295                 300

 Gln Glu Gly Arg Tyr Arg His Pro Gly Cys Tyr Thr Cys Ala Asp
                 305                 310                 315

 Cys Gly Leu Asn Leu Lys Met Arg Gly His Phe Trp Val Gly Asp
                 320                 325                 330

 Glu Leu Tyr Cys Glu Lys His Ala Arg Gln Arg Tyr Ser Ala Pro
                 335                 340                 345

 Ala Thr Leu Ser Ser Arg Ala
                 350

<210> 3361
<211> 1530
<212> DNA
<213> Homo sapien

<400> 3361
 agttcccagc tgtccgaaag gtcttcggaa cttcggctct aaagcgttcc 50

 tcagcgccat ccgcccggaa acacgagcga cagagaaaag gtccgcgagg 100

 ccggcagact ccagagtggc tgggtccgag cgcggggcgg gttgccgaag 150

 ggcctcggcc tgggctgcgt gctggagagc ggggacgggg ccgactcacc 200

 agaggctgca gcaacaggtc cactttgctc tccagtctct ttctccgaca 250

 ccgctgaggc ggtttcccac cgacttcctt tccatacagc accggcaggc 300

 accggggtga agggtcataa aaatggcgct ggccgctcgt ttgctacccc 350

 agttcctgca ctctcggtcg ctgccctgcg gggccgtccg actccggact 400

 cctgctgtgg ccgaggtgag gctgccgtcg gccacacttt gctacttctg 450

 ccgctgtcgc ctcggcttgg gagcggcgtt atttccacga agcgctaggg 500

 ccttggcagc ctcggcgcta cctgcccagg gctcccggtg gccagtgctc 550

 agcagcccgg gactccccgc agccttcgct tctttccctg cctgccctca 600

 gcgcagctac agcacggagg agaagcccca gcagcaccag aaaaccaaga 650

 tgatcgtcct gggattctcc aaccccatca actgggttag gactcgaatt 700

 aaggccttcc ttatctgggc ctatttcgac aaagagttca gcatcacaga 750

 gttctccgag ggagcgaagc aggcttttgc tcatgtatcc aagttgctgt 800

 cacagtgtaa atttgatctg ttggaagaac ttgtggccaa agaggtgcta 850

 catgcattga aagaaaaggt tacttcacta cctgacaacc ataaaaatgc 900

 ccttgctgct aacatagatg aaattgtatt tacatcaaca ggaggcatct 950

 ccatttacta tgatgagaaa ggaaggaagt ttgttaacat cctgatgtgc 1000

 ttttggtatc taaccagtgc caacatcccc agtgaaactt taagaggagc 1050

 cagtgtattc caggttaagt tggggaatca gaatgtggaa actaaacaac 1100

 ttcttagtgc aagctatgag tttcagaggg agttcacaca aggagtaaag 1150

 cctgactgga ccattgcacg gattgaacac tcaaaattat tagaataatt 1200

 ttcttggaaa aatcagctta tggactttag cagttgctgt gaaaaactaa 1250

 ggaagaaaaa ttttggggtc atttgatctt cacttaatct aagtctgtga 1300

 attactttta tattattttg aaatactcct tgcagtatat tggcatgata 1350

 cagtaaaagc attttccaca gattgttatc accttcttta aaagaagtca 1400

 aaatttaaaa aatacaatag cacgttgttg gtgtcatatt caataacatt 1450

 tccaatgcta catataattt tatagacata ataaagaagg tattgaaaaa 1500

 actaaaaaaa aaaaaaaaaa aaaaaaaaaa 1530

<210> 3362
<211> 291
<212> PRT
<213> Homo sapien

<400> 3362
 Met Ala Leu Ala Ala Arg Leu Leu Pro Gln Phe Leu His Ser Arg
   1               5                  10                  15

 Ser Leu Pro Cys Gly Ala Val Arg Leu Arg Thr Pro Ala Val Ala
                  20                  25                  30

 Glu Val Arg Leu Pro Ser Ala Thr Leu Cys Tyr Phe Cys Arg Cys
                  35                  40                  45

 Arg Leu Gly Leu Gly Ala Ala Leu Phe Pro Arg Ser Ala Arg Ala
                  50                  55                  60

 Leu Ala Ala Ser Ala Leu Pro Ala Gln Gly Ser Arg Trp Pro Val
                  65                  70                  75

 Leu Ser Ser Pro Gly Leu Pro Ala Ala Phe Ala Ser Phe Pro Ala
                  80                  85                  90

 Cys Pro Gln Arg Ser Tyr Ser Thr Glu Glu Lys Pro Gln Gln His
                  95                 100                 105

 Gln Lys Thr Lys Met Ile Val Leu Gly Phe Ser Asn Pro Ile Asn
                 110                 115                 120

 Trp Val Arg Thr Arg Ile Lys Ala Phe Leu Ile Trp Ala Tyr Phe
                 125                 130                 135

 Asp Lys Glu Phe Ser Ile Thr Glu Phe Ser Glu Gly Ala Lys Gln
                 140                 145                 150

 Ala Phe Ala His Val Ser Lys Leu Leu Ser Gln Cys Lys Phe Asp
                 155                 160                 165

 Leu Leu Glu Glu Leu Val Ala Lys Glu Val Leu His Ala Leu Lys
                 170                 175                 180

 Glu Lys Val Thr Ser Leu Pro Asp Asn His Lys Asn Ala Leu Ala
                 185                 190                 195

 Ala Asn Ile Asp Glu Ile Val Phe Thr Ser Thr Gly Gly Ile Ser
                 200                 205                 210

 Ile Tyr Tyr Asp Glu Lys Gly Arg Lys Phe Val Asn Ile Leu Met
                 215                 220                 225

 Cys Phe Trp Tyr Leu Thr Ser Ala Asn Ile Pro Ser Glu Thr Leu
                 230                 235                 240

 Arg Gly Ala Ser Val Phe Gln Val Lys Leu Gly Asn Gln Asn Val
                 245                 250                 255

 Glu Thr Lys Gln Leu Leu Ser Ala Ser Tyr Glu Phe Gln Arg Glu
                 260                 265                 270

 Phe Thr Gln Gly Val Lys Pro Asp Trp Thr Ile Ala Arg Ile Glu
                 275                 280                 285

 His Ser Lys Leu Leu Glu
                 290

<210> 3363
<211> 3837
<212> DNA
<213> Homo sapien

<400> 3363
 gtcgaatggt ttgttggcag ggtgtcctgg tggattggtt tctgtaagtt 50

 cagattctca taaatcgtgt gagcgtcgcc gacacctctg agataaaagg 100

 gcccctttcg actagcctct gctgaaagga cctagaagaa tcccttagga 150

 tgaagctgag tcttaccaag gtagttaatg gctgtcgcct aggaaaaata 200

 aaaaacctgg gcaaaacagg ggaccacacc atggatattc caggctgcct 250

 tctgtatacc aagactggct ccgccccaca cctcacccat cacacgctgc 300

 ataatatcca cggggttcct gccatggctc agcttacgct gtcatcccta 350

 gcagaacatc atgaagtctt gacagaatat aaagaaggag ttggaaagtt 400

 tataggcatg ccagaatcac tcttgtactg ctccctgcac gatccagtca 450

 gcccctgccc ggctggttat gtaacaaaca agtctgtgtc tgtgtggagt 500

 gttgcaggac gagtggaaat gactgtttcc aagttcatgg caattcagaa 550

 ggcccttcag ccagactggt tccagtgcct ctccgatgga gaagtatctt 600

 gtaaggaagc aacttccata aaaagggtca gaaagtctgt tgaccgatca 650

 cttcttttct tggataactg tctgcggctg caggaagagt cagaggttct 700

 tcagaagagt gtgatcattg gagtgattga aggtggagat gtgatggaag 750

 agaggctgag gtcagcacga gagacagcca agcggcctgt gggtggcttc 800

 cttctggatg gttttcaagg aaatccaaca accctggagg ctagactacg 850

 cttgctgtca tcagtcactg cagagctgcc ggaggacaag ccaaggctca 900

 tatctggtgt tagtcggcca gatgaggtgc tcgagtgtat tgaaagagga 950

 gtggacttat ttgagagttt tttcccttat caagtaacag agcggggatg 1000

 tgccctgact ttcagttttg attaccagcc gaatcctgaa gagacactac 1050

 tacaacaaaa tggaacacaa gaagaaataa aatgtatgga tcaaataaag 1100

 aaaattgaaa caactggttg caaccaagaa ataacatcat ttgaaattaa 1150

 tctgaaggaa aaaaagtacc aggaggactt taacccgctg gtgagaggat 1200

 gttcctgtta ctgctgtaag aatcacactc gggcatacat ccaccatctg 1250

 ctggtgacca atgagctgct ggccggagtc ctgcttatga tgcacaactt 1300

 tgaacactac tttgggtttt tccattacat ccgggaagca ctaaaaagtg 1350

 acaaactggc acagttgaaa gagctcatcc acaggcaagc atcttgagat 1400

 cttgcaaata caagtctcac tcttcacact gagcctgtac cactgttgta 1450

 acatgggaag acgtgaagaa gaaataatct gagctttaat tatttatatt 1500

 tggatataag gtctgcttaa ataaagaatc tttgtaccaa actgcccaca 1550

 tgagggtgaa gagatttcct caaaagactt aaatgacctg gattgatcag 1600

 agagaattga actgtgacct ttaaaacttc tagactaatt cttttagttg 1650

 atagagattc atttagtcaa agacaaaagc tttaactgtg agggcacagc 1700

 cttgaagtgg gagtgatgag attctgaggg acccatgaat tggattgagg 1750

 cttgagggga aatggtgtga gacgaatggg ctctggacat atgcctgttg 1800

 atttgagaag aaatctggct ggtttgaggg tttcctttag ttcaccctca 1850

 tactctcagg agactcttct ggatactttt gtcttccacc ctgccctggc 1900

 agtgcagcca atcagaaatg gctcttgtga cttaactggg cttggatatc 1950

 cctggaatgt ggggcttgaa cattgctcct gtgatgatca tctgtcccag 2000

 gtcacactcc ttcatttgac cacatggcct atttgcaact tctttttaga 2050

 gccaatgtaa ttgcctgtta ggagccagaa gtttgcccag ctgctttctt 2100

 ctggttgtac agatccattg tggtctgcct tccaggctca ttaatagtct 2150

 aactacgtaa taactgaaga cctatctctt gtgaagattc attctcaatg 2200

 tgttcacttg gacagagccc tgcctggcct aacgattaga gggttagtct 2250

 ccatcctgct cagatatgac tcctgggcaa ttcacttaac ttctccatgg 2300

 ctgcttcctg ctgaataaat agggacaggc ataatggata ggaatgaatg 2350

 aacttttaag atactgtcta gctctaaaat tggaagaaca aaaagtttta 2400

 gattagagtc atagccttaa tagccctagt tgtcatcctg ggagacaggc 2450

 aacagtagag atatttgaga gcctaaagag aggtttggcc tgtgggtttt 2500

 taagtggtta ttgaattggt atcaggagat cctgaggctg gtaggggaag 2550

 gtaattcttt ctaagttacc tctgtatttt tcaagttttc tataaggaat 2600

 acacatacac ccacatgcac acaccatagt ttttatacaa acagcaataa 2650

 caaaaccaaa aagatgcccc tttttttgta gggataagaa atacatttgt 2700

 tttatacttc tatgctatat tttgctattc aaaatttagt gggcattact 2750

 taacattgtt tctaattatt ttgtggctgc tgtatgtttt atgtgttggg 2800

 agcccattgt attaggccgt tcttggattg ctataaagaa atacctgaga 2850

 ctgggtaatt tggttttttg gttttttggg gttttttttg agacggagcc 2900

 ttgctctgtc gcccaggctg gagtgcagtg gcgcgatctc ggctctatgc 2950

 aacctccacc tcctgggttc atgccattct cctgcctcag cctcccgagt 3000

 agctgggact acaggcgccc gccaccatgc ctggctaatt ttttatattt 3050

 ttagtagaga tggggtttca ccgtatgagc caggatggtc tcgatctcct 3100

 gacctcatga tccacaagac tgggtaatct gtaaagaaaa gaggtttaat 3150

 tggctcatgg ctctgcaggc tttacaggaa gcatggtact ggcgtctgct 3200

 tggtttctgg ggaggcctcc ggaagcttat agtcatggca gaaggtgaag 3250

 ggggagcagg cacatcacat gacaaaagca ggaacaagac tcagagcaag 3300

 aagtcactta tcaccaaggg gatggcccag gccattcatg agggatccac 3350

 ctttgtgctc caaacacctc ccaccaggcc ccacctccag tattggggat 3400

 tacatttcaa cttgaggttt gggcgggaac aaatagtcaa attatattac 3450

 ccatctacat ggttttcttt ttcttagtat gggagtgtcc atgaataaat 3500

 tcatgggcat cctcataact cttccatgaa tggcaagggg tacttatgga 3550

 aaacagtttt ccaaagatct gattgttttg aaatgtgtta gattggactt 3600

 gttcaaatgt tcatattttt gttctatgct aaatgcatcg ttaggggagt 3650

 agtggtaaat attccagaat ccatatgaaa ttcatgagtt tatttatgtc 3700

 taaaacactg aaaactgtgt ccaatatcgt tcagtttcct gggtcttttt 3750

 cttattagca catttgagaa aaatattcct ttcctttatt gtagtaaatc 3800

 tattaaaggc aatagccaat aaaacatttt taatttt 3837

<210> 3364
<211> 415
<212> PRT
<213> Homo sapien

<400> 3364
 Met Lys Leu Ser Leu Thr Lys Val Val Asn Gly Cys Arg Leu Gly
   1               5                  10                  15

 Lys Ile Lys Asn Leu Gly Lys Thr Gly Asp His Thr Met Asp Ile
                  20                  25                  30

 Pro Gly Cys Leu Leu Tyr Thr Lys Thr Gly Ser Ala Pro His Leu
                  35                  40                  45

 Thr His His Thr Leu His Asn Ile His Gly Val Pro Ala Met Ala
                  50                  55                  60

 Gln Leu Thr Leu Ser Ser Leu Ala Glu His His Glu Val Leu Thr
                  65                  70                  75

 Glu Tyr Lys Glu Gly Val Gly Lys Phe Ile Gly Met Pro Glu Ser
                  80                  85                  90

 Leu Leu Tyr Cys Ser Leu His Asp Pro Val Ser Pro Cys Pro Ala
                  95                 100                 105

 Gly Tyr Val Thr Asn Lys Ser Val Ser Val Trp Ser Val Ala Gly
                 110                 115                 120

 Arg Val Glu Met Thr Val Ser Lys Phe Met Ala Ile Gln Lys Ala
                 125                 130                 135

 Leu Gln Pro Asp Trp Phe Gln Cys Leu Ser Asp Gly Glu Val Ser
                 140                 145                 150

 Cys Lys Glu Ala Thr Ser Ile Lys Arg Val Arg Lys Ser Val Asp
                 155                 160                 165

 Arg Ser Leu Leu Phe Leu Asp Asn Cys Leu Arg Leu Gln Glu Glu
                 170                 175                 180

 Ser Glu Val Leu Gln Lys Ser Val Ile Ile Gly Val Ile Glu Gly
                 185                 190                 195

 Gly Asp Val Met Glu Glu Arg Leu Arg Ser Ala Arg Glu Thr Ala
                 200                 205                 210

 Lys Arg Pro Val Gly Gly Phe Leu Leu Asp Gly Phe Gln Gly Asn
                 215                 220                 225

 Pro Thr Thr Leu Glu Ala Arg Leu Arg Leu Leu Ser Ser Val Thr
                 230                 235                 240

 Ala Glu Leu Pro Glu Asp Lys Pro Arg Leu Ile Ser Gly Val Ser
                 245                 250                 255

 Arg Pro Asp Glu Val Leu Glu Cys Ile Glu Arg Gly Val Asp Leu
                 260                 265                 270

 Phe Glu Ser Phe Phe Pro Tyr Gln Val Thr Glu Arg Gly Cys Ala
                 275                 280                 285

 Leu Thr Phe Ser Phe Asp Tyr Gln Pro Asn Pro Glu Glu Thr Leu
                 290                 295                 300

 Leu Gln Gln Asn Gly Thr Gln Glu Glu Ile Lys Cys Met Asp Gln
                 305                 310                 315

 Ile Lys Lys Ile Glu Thr Thr Gly Cys Asn Gln Glu Ile Thr Ser
                 320                 325                 330

 Phe Glu Ile Asn Leu Lys Glu Lys Lys Tyr Gln Glu Asp Phe Asn
                 335                 340                 345

 Pro Leu Val Arg Gly Cys Ser Cys Tyr Cys Cys Lys Asn His Thr
                 350                 355                 360

 Arg Ala Tyr Ile His His Leu Leu Val Thr Asn Glu Leu Leu Ala
                 365                 370                 375

 Gly Val Leu Leu Met Met His Asn Phe Glu His Tyr Phe Gly Phe
                 380                 385                 390

 Phe His Tyr Ile Arg Glu Ala Leu Lys Ser Asp Lys Leu Ala Gln
                 395                 400                 405

 Leu Lys Glu Leu Ile His Arg Gln Ala Ser
                 410                 415

<210> 3365
<211> 3221
<212> DNA
<213> Homo sapien

<400> 3365
 tgtcaaaagc ctgcacacga gacccccgtg ggccaggact gacttcctcc 50

 ccacacaggg ctgggcgggg caagcaggaa ggagcctgtt acagtcaagg 100

 tgacgcatcc ttgccgggcc agcccgaaca gcagctgggt cggcaagcga 150

 caggagcacg ggtcatcttt tccccagagg cgtcggaatg gacctgtgcc 200

 acccagagcc cgcggagctg agcagcgggg agacggaaga gttacagagg 250

 atcaagtggc accgaaagca gctcctggag gacatccaga agctgaagga 300

 tgagattgca gatgtgtttg cccaaatcga ctgcttcgag agtgcggagg 350

 agagccggat ggcccagaag gagaaggagc tgtgtattgg gcgcaagaag 400

 ttcaacatgg accccgccaa gggtatccag tatttcattg agcacaagct 450

 gctgacccct gacgtccagg acattgcacg gttcctgtat aaaggcgagg 500

 gcctcaacaa gacagccatt ggtacctacc tgggggagag ggatcccatc 550

 aacctgcagg tcctccaggc cttcgtggac tgccacgagt tcgccaacct 600

 caacctcgtc caggccctca ggcagttcct gtggagcttc cggctgccgg 650

 gcgaggccca gaagatagac cggatgatgg aggcctttgc cactcgatac 700

 tgcctctgca acccaggcgt cttccagtcc acagacacct gctacgtgtt 750

 gtccttctcc atcatcatgc tcaacaccag cctccacaat cccaacgtcc 800

 gggacaggcc gcctttcgag cgctttgtgt ccatgaaccg cggcatcaac 850

 aatggtagcg acctgcccga ggaccagctg cggaacctct tcgacagcat 900

 caagagtgag ccattctcca tccctgagga cgacggcaat gacctcactc 950

 acaccttctt caatccagac cgggagggtt ggctgctcaa gctagggggc 1000

 cgcgtgaaga cgtggaaacg gcgctggttc atcctgaccg acaactgcct 1050

 ctactacttc gagttcacca ctgacaagga gccacgggga attatacctc 1100

 ttgagaacct ctcggtgcag aaggtggatg accccaagaa gccattctgc 1150

 ctggagctct acaaccctag ctgccgaggc cagaaaatca aggcctgcaa 1200

 gaccgatggc gacggcaggg tggtggaggg caagcacgaa tcgtaccgca 1250

 tctcagccac cagtgccgag gaacgtgacc agtggatcga gtccatccga 1300

 gccagcatca cccgtgtccc cttctacgac ctggtctcta ctcggaagaa 1350

 gaagattgcc agcaagcagt gagattcctg gaggtggcac tgggggctgg 1400

 tcaccctgag agtcccatcg cctgcagcac ctggagaccc acctcccacc 1450

 ccagtgcact cttttgggcc acagacatca ttgctgttcc ccgttacctc 1500

 gagctgactc tagaggggaa ggcagagctc aggagggtgg gtgggagctg 1550

 cagtgggctc agagtccagc aatgaggccc cctggcctgg gcacccagct 1600

 gcaggcccct gccctacgtg cactacagga aggggtgagg agagcagcca 1650

 gaggaaaacc agccccagaa tgctgcaact tctcttctct ctggacttcg 1700

 gtgtcctcgg ctctgaaggc gctctctgca cttagatgct gtcagccctc 1750

 aacgtaggag gggccgtggg gtccctaagt gattcttctc cctggcaagg 1800

 ctcttccttt tcagggatat ctctgccaac ccttcccctg tcctcgggtt 1850

 gggcttggcc ctctctgcct gagagagctc agcacacaca cagctcagac 1900

 ccacggacag gaccccggga cagaaccccg ggagcactgc cctaggagcc 1950

 tggaccccac gagctcagtc ccagctctgc ctctgactcg ctgtgtaccc 2000

 tctgccaagt catgcccatt ctctagttct tgcaaaactg cagtgtttgg 2050

 actagaaacg tattggcccc tgctagccct gtgctccagc ttccagctgg 2100

 agatggcagc cgttatttgc ggagcccagg ctgactccgg attcaacgtt 2150

 gctggggaga gaaaagcagt atagactcca ccttccagga tgtccatttc 2200

 ggggagagga gcaggtggga ccctcaagaa aatgacggag aacatcccag 2250

 acagatggga ctcaagcagg atgggtgcta tatccaagaa gccaagaagg 2300

 gagagtttcg tgcactgtgg ttaacaggag ggccgcctgg aggcagtggc 2350

 tgagccagaa agtaacacag agctcatgct tggagagata gagtcttggc 2400

 catggctttc ctgcaagacc actgacgagc agtcccatgg tgataaaggg 2450

 cagcccggcg ggtcccagca tctcgagacc ctctgcagaa gtattatcag 2500

 agtagagctg acttccagta cccgggcagc cagctctgtc tccagggagg 2550

 cctggcctgg aggaggagtc cactaacagg aaacacttct caccccctca 2600

 cacaggccca ggggagcccc tggagggaaa ttccttggca ggggaacagg 2650

 aaatgtggtc gcctctgccc cactgccagc ctgagtgggc aaggaagcag 2700

 gtggatcccc cagaaggaac cgcagctcgc gaggcacctc tcctcgtccc 2750

 cacccacccc cacatttgca caccttccac agggtcagga tggagtagct 2800

 gccttgcgag gtggtgagac tcctgtctct ggaggtctgc aagcactggt 2850

 agtgatattg cagcagacaa ggtctgggtt gggcgtctgc aggaggagac 2900

 cttgtgggac atctgaggac atccgcagat tcttgtcagc ctgtgaacta 2950

 ggccctgcct ctgtcacctc attggtccat gaaggagcag ccaggggtgg 3000

 tggaaggagc actgggctag gggtcagggg tcagagattc tgtcctgctc 3050

 ctgggatgca ctggctactc ccttagtcta ctcccttccc ctctctggtc 3100

 ctcagcttcc tccatcatgg aggagatggg atcatggatt ttctgggcat 3150

 aagtggctgt tctgggagtc attccaaaga gagaataaaa ctcctgatcc 3200

 aaaaaaaaaa aaaaaaaaaa a 3221

<210> 3366
<211> 394
<212> PRT
<213> Homo sapien

<400> 3366
 Met Asp Leu Cys His Pro Glu Pro Ala Glu Leu Ser Ser Gly Glu
   1               5                  10                  15

 Thr Glu Glu Leu Gln Arg Ile Lys Trp His Arg Lys Gln Leu Leu
                  20                  25                  30

 Glu Asp Ile Gln Lys Leu Lys Asp Glu Ile Ala Asp Val Phe Ala
                  35                  40                  45

 Gln Ile Asp Cys Phe Glu Ser Ala Glu Glu Ser Arg Met Ala Gln
                  50                  55                  60

 Lys Glu Lys Glu Leu Cys Ile Gly Arg Lys Lys Phe Asn Met Asp
                  65                  70                  75

 Pro Ala Lys Gly Ile Gln Tyr Phe Ile Glu His Lys Leu Leu Thr
                  80                  85                  90

 Pro Asp Val Gln Asp Ile Ala Arg Phe Leu Tyr Lys Gly Glu Gly
                  95                 100                 105

 Leu Asn Lys Thr Ala Ile Gly Thr Tyr Leu Gly Glu Arg Asp Pro
                 110                 115                 120

 Ile Asn Leu Gln Val Leu Gln Ala Phe Val Asp Cys His Glu Phe
                 125                 130                 135

 Ala Asn Leu Asn Leu Val Gln Ala Leu Arg Gln Phe Leu Trp Ser
                 140                 145                 150

 Phe Arg Leu Pro Gly Glu Ala Gln Lys Ile Asp Arg Met Met Glu
                 155                 160                 165

 Ala Phe Ala Thr Arg Tyr Cys Leu Cys Asn Pro Gly Val Phe Gln
                 170                 175                 180

 Ser Thr Asp Thr Cys Tyr Val Leu Ser Phe Ser Ile Ile Met Leu
                 185                 190                 195

 Asn Thr Ser Leu His Asn Pro Asn Val Arg Asp Arg Pro Pro Phe
                 200                 205                 210

 Glu Arg Phe Val Ser Met Asn Arg Gly Ile Asn Asn Gly Ser Asp
                 215                 220                 225

 Leu Pro Glu Asp Gln Leu Arg Asn Leu Phe Asp Ser Ile Lys Ser
                 230                 235                 240

 Glu Pro Phe Ser Ile Pro Glu Asp Asp Gly Asn Asp Leu Thr His
                 245                 250                 255

 Thr Phe Phe Asn Pro Asp Arg Glu Gly Trp Leu Leu Lys Leu Gly
                 260                 265                 270

 Gly Arg Val Lys Thr Trp Lys Arg Arg Trp Phe Ile Leu Thr Asp
                 275                 280                 285

 Asn Cys Leu Tyr Tyr Phe Glu Phe Thr Thr Asp Lys Glu Pro Arg
                 290                 295                 300

 Gly Ile Ile Pro Leu Glu Asn Leu Ser Val Gln Lys Val Asp Asp
                 305                 310                 315

 Pro Lys Lys Pro Phe Cys Leu Glu Leu Tyr Asn Pro Ser Cys Arg
                 320                 325                 330

 Gly Gln Lys Ile Lys Ala Cys Lys Thr Asp Gly Asp Gly Arg Val
                 335                 340                 345

 Val Glu Gly Lys His Glu Ser Tyr Arg Ile Ser Ala Thr Ser Ala
                 350                 355                 360

 Glu Glu Arg Asp Gln Trp Ile Glu Ser Ile Arg Ala Ser Ile Thr
                 365                 370                 375

 Arg Val Pro Phe Tyr Asp Leu Val Ser Thr Arg Lys Lys Lys Ile
                 380                 385                 390

 Ala Ser Lys Gln


<210> 3367
<211> 2206
<212> DNA
<213> Homo sapien

<400> 3367
 cgcggggcca gggcggcggc ccccagggag ttggcaggat ggcagagggc 50

 aaggcaggcg gcgcggccgg cctcttcgcc aagcaggtgc agaagaagtt 100

 tagcagggcc caggagaagg tgctgcagaa attggggaaa gctgtagaaa 150

 ccaaagatga acgatttgaa caaagcgcta acaacttcta ccaacaacag 200

 gcagaaggcc acaagctgta caaggacctg aagaacttcc ttagtgcagt 250

 caaagtgatg catgaaagtt caaaaagagt gtcagaaacc ctgcaggaga 300

 tctacagcag cgagtgggat ggtcatgagg agctgaaggc catcgtatgg 350

 aataatgatc tcctttggga agactacgag gagaaactgg ctgaccaggc 400

 tgtaaggacc atggaaatct atgttgccca gttcagtgaa attaaggaga 450

 gaattgccaa gcggggtcgg aaactcgtgg actatgacag tgcccgacac 500

 cacctggagg cagtgcagaa tgccaagaag aaagatgagg ccaagactgc 550

 caaggcagag gaagagttca acaaagccca gactgtgttt gaagatctga 600

 accaagaact actagaggag ctgcctattc tttataatag tcgtattggc 650

 tgctatgtga ccatcttcca aaacatttcc aacttgaggg atgtcttcta 700

 cagggaaatg agcaagctga accacaatct ctacgaggtg atgagcaaac 750

 tggagaagca acattccaat aaagtctttg tggtgaaggg actgtcaagc 800

 agcagcaggc gctctttagt catttctccc ccagttcgaa cagctacagt 850

 ctccagtcct cttacctcac ctactagtcc ctctacactt tccttgaaga 900

 gtgagagtga atctgtctca gcaactgaag atctggcacc tgatgcagcc 950

 caaggggaag acaattctga gatcaaggag ctcttagaag aggaggaaat 1000

 agagaaggaa ggatctgaag caagctcctc tgaggaagat gagcctctac 1050

 cagcctgcaa tggccccgcc caggcccagc cctctcctac cactgaaagg 1100

 gccaagtccc aggaggaagt tctccccagc tccacaactc catcaccagg 1150

 cggagccctg agcccttcag ggcagccttc atcatctgcc acagaagtag 1200

 tcctccgaac ccgcaccgca agtgaaggat ctgaacaacc aaagaagaga 1250

 gcctctatcc agaggacctc agcaccccct agtaggcctc ctccacccag 1300

 agccactgca agccccaggc cctcctcagg gaacatacct tccagcccta 1350

 cagcctctgg agggggttca cccaccagcc ctagggcctc cttggggact 1400

 gggactgcaa gtcctaggac ctccctagag gtctctccta atccagaacc 1450

 accagagaag ccagtaagaa ctcctgaggc caaagaaaat gaaaacatcc 1500

 acaatcagaa ccctgaagaa ctttgtactt cccccacctt aatgacatct 1550

 caggttgctt cagagcctgg agaggcaaag aagatggaag acaaggaaaa 1600

 ggataataag cttatctcag ctgactcctc ggagggccaa gaccagcttc 1650

 aagtctccat ggtaccagaa aacaacaacc tcacagcacc tgaacctcaa 1700

 gaagaggtat ccacaagtga aaatccacaa ctctgaagag aaactaccaa 1750

 gactcctcct gccccaaacc tcgccagaga agctcttcaa ccagagggta 1800

 taggtcagag ggatataaga gccagcatcc atccctgggt tctcagtagg 1850

 aatgctggtg ctgtctaaag acctggcatt aatggaggcg gaggagcagc 1900

 cttacgggag ggatggaggg aggcaggctg gggagaagag aacattagac 1950

 tcagggaata tttaattctg gttttagcat tattagaata agactttata 2000

 cattaactaa agtggagctt taatcactat aaaaagcaaa agtatctata 2050

 gacacagaca cttgcctata cagagacata accacacaca ctcagaggat 2100

 agtgaacaaa tctgtctttg acttacgacc cattttgcaa gacttaaagc 2150

 cggaagaaca cattttcaga ttgttaaata aagtctgatt ctgactaaaa 2200

 aaaaaa 2206

<210> 3368
<211> 565
<212> PRT
<213> Homo sapien

<400> 3368
 Met Ala Glu Gly Lys Ala Gly Gly Ala Ala Gly Leu Phe Ala Lys
   1               5                  10                  15

 Gln Val Gln Lys Lys Phe Ser Arg Ala Gln Glu Lys Val Leu Gln
                  20                  25                  30

 Lys Leu Gly Lys Ala Val Glu Thr Lys Asp Glu Arg Phe Glu Gln
                  35                  40                  45

 Ser Ala Asn Asn Phe Tyr Gln Gln Gln Ala Glu Gly His Lys Leu
                  50                  55                  60

 Tyr Lys Asp Leu Lys Asn Phe Leu Ser Ala Val Lys Val Met His
                  65                  70                  75

 Glu Ser Ser Lys Arg Val Ser Glu Thr Leu Gln Glu Ile Tyr Ser
                  80                  85                  90

 Ser Glu Trp Asp Gly His Glu Glu Leu Lys Ala Ile Val Trp Asn
                  95                 100                 105

 Asn Asp Leu Leu Trp Glu Asp Tyr Glu Glu Lys Leu Ala Asp Gln
                 110                 115                 120

 Ala Val Arg Thr Met Glu Ile Tyr Val Ala Gln Phe Ser Glu Ile
                 125                 130                 135

 Lys Glu Arg Ile Ala Lys Arg Gly Arg Lys Leu Val Asp Tyr Asp
                 140                 145                 150

 Ser Ala Arg His His Leu Glu Ala Val Gln Asn Ala Lys Lys Lys
                 155                 160                 165

 Asp Glu Ala Lys Thr Ala Lys Ala Glu Glu Glu Phe Asn Lys Ala
                 170                 175                 180

 Gln Thr Val Phe Glu Asp Leu Asn Gln Glu Leu Leu Glu Glu Leu
                 185                 190                 195

 Pro Ile Leu Tyr Asn Ser Arg Ile Gly Cys Tyr Val Thr Ile Phe
                 200                 205                 210

 Gln Asn Ile Ser Asn Leu Arg Asp Val Phe Tyr Arg Glu Met Ser
                 215                 220                 225

 Lys Leu Asn His Asn Leu Tyr Glu Val Met Ser Lys Leu Glu Lys
                 230                 235                 240

 Gln His Ser Asn Lys Val Phe Val Val Lys Gly Leu Ser Ser Ser
                 245                 250                 255

 Ser Arg Arg Ser Leu Val Ile Ser Pro Pro Val Arg Thr Ala Thr
                 260                 265                 270

 Val Ser Ser Pro Leu Thr Ser Pro Thr Ser Pro Ser Thr Leu Ser
                 275                 280                 285

 Leu Lys Ser Glu Ser Glu Ser Val Ser Ala Thr Glu Asp Leu Ala
                 290                 295                 300

 Pro Asp Ala Ala Gln Gly Glu Asp Asn Ser Glu Ile Lys Glu Leu
                 305                 310                 315

 Leu Glu Glu Glu Glu Ile Glu Lys Glu Gly Ser Glu Ala Ser Ser
                 320                 325                 330

 Ser Glu Glu Asp Glu Pro Leu Pro Ala Cys Asn Gly Pro Ala Gln
                 335                 340                 345

 Ala Gln Pro Ser Pro Thr Thr Glu Arg Ala Lys Ser Gln Glu Glu
                 350                 355                 360

 Val Leu Pro Ser Ser Thr Thr Pro Ser Pro Gly Gly Ala Leu Ser
                 365                 370                 375

 Pro Ser Gly Gln Pro Ser Ser Ser Ala Thr Glu Val Val Leu Arg
                 380                 385                 390

 Thr Arg Thr Ala Ser Glu Gly Ser Glu Gln Pro Lys Lys Arg Ala
                 395                 400                 405

 Ser Ile Gln Arg Thr Ser Ala Pro Pro Ser Arg Pro Pro Pro Pro
                 410                 415                 420

 Arg Ala Thr Ala Ser Pro Arg Pro Ser Ser Gly Asn Ile Pro Ser
                 425                 430                 435

 Ser Pro Thr Ala Ser Gly Gly Gly Ser Pro Thr Ser Pro Arg Ala
                 440                 445                 450

 Ser Leu Gly Thr Gly Thr Ala Ser Pro Arg Thr Ser Leu Glu Val
                 455                 460                 465

 Ser Pro Asn Pro Glu Pro Pro Glu Lys Pro Val Arg Thr Pro Glu
                 470                 475                 480

 Ala Lys Glu Asn Glu Asn Ile His Asn Gln Asn Pro Glu Glu Leu
                 485                 490                 495

 Cys Thr Ser Pro Thr Leu Met Thr Ser Gln Val Ala Ser Glu Pro
                 500                 505                 510

 Gly Glu Ala Lys Lys Met Glu Asp Lys Glu Lys Asp Asn Lys Leu
                 515                 520                 525

 Ile Ser Ala Asp Ser Ser Glu Gly Gln Asp Gln Leu Gln Val Ser
                 530                 535                 540

 Met Val Pro Glu Asn Asn Asn Leu Thr Ala Pro Glu Pro Gln Glu
                 545                 550                 555

 Glu Val Ser Thr Ser Glu Asn Pro Gln Leu
                 560                 565

<210> 3369
<211> 3434
<212> DNA
<213> Homo sapien

<400> 3369
 gccccgctgc ccacctgccc gcctgcccac ctgcccaggt gcgagtgcag 50

 ccccgcgcgc cggcctgaga gccctgtgga caacctcgtc attgtcaggc 100

 acagagcggt agaccctgct tctctaagtg ggcagcggac agcggcacgc 150

 acatttcacc tgtcccgcag acaacagcac catctgcttg ggagaaccct 200

 ctcccttctc tgagaaagaa agatgtcgaa tgggtattcc acagacgaga 250

 atttccgcta tctcatctcg tgcttcaggg ccagggtgaa aatgtacatc 300

 caggtggagc ctgtgctgga ctacctgacc tttctgcctg cagaggtgaa 350

 ggagcagatt cagaggacag tcgccacctc cgggaacatg caggcagttg 400

 aactgctgct gagcaccttg gagaagggag tctggcacct tggttggact 450

 cgggaattcg tggaggccct ccggagaacc ggcagccctc tggccgcccg 500

 ctacatgaac cctgagctca cggacttgcc ctctccatcg tttgagaacg 550

 ctcatgatga atatctccaa ctgctgaacc tccttcagcc cactctggtg 600

 gacaagcttc tagttagaga cgtcttggat aagtgcatgg aggaggaact 650

 gttgacaatt gaagacagaa accggattgc tgctgcagaa aacaatggaa 700

 atgaatcagg tgtaagagag ctactaaaaa ggattgtgca gaaagaaaac 750

 tggttctctg catttctgaa tgttcttcgt caaacaggaa acaatgaact 800

 tgtccaagag ttaacaggct ctgattgctc agaaagcaat gcagagattg 850

 agaatttatc acaagttgat ggtcctcaag tggaagagca acttctttca 900

 accacagttc agccaaatct ggagaaggag gtctggggca tggagaataa 950

 ctcatcagaa tcatcttttg cagattcttc tgtagtttca gaatcagaca 1000

 caagtttggc agaaggaagt gtcagctgct tagatgaaag tcttggacat 1050

 aacagcaaca tgggcagtga ttcaggcacc atgggaagtg attcagatga 1100

 agagaatgtg gcagcaagag catccccgga gccagaactc cagctcaggc 1150

 cttaccaaat ggaagttgcc cagccagcct tggaagggaa gaatatcatc 1200

 atctgcctcc ctacagggag tggaaaaacc agagtggctg tttacattgc 1250

 caaggatcac ttagacaaga agaaaaaagc atctgagcct ggaaaagtta 1300

 tagttcttgt caataaggta ctgctagttg aacagctctt ccgcaaggag 1350

 ttccaaccat ttttgaagaa atggtatcgt gttattggat taagtggtga 1400

 tacccaactg aaaatatcat ttccagaagt tgtcaagtcc tgtgatatta 1450

 ttatcagtac agctcaaatc cttgaaaact ccctcttaaa cttggaaaat 1500

 ggagaagatg ctggtgttca attgtcagac ttttccctca ttatcattga 1550

 tgaatgtcat cacaccaaca aagaagcagt gtataataac atcatgaggc 1600

 attatttgat gcagaagttg aaaaacaata gactcaagaa agaaaacaaa 1650

 ccagtgattc cccttcctca gatactggga ctaacagctt cacctggtgt 1700

 tggaggggcc acgaagcaag ccaaagctga agaacacatt ttaaaactat 1750

 gtgccaatct tgatgcattt actattaaaa ctgttaaaga aaaccttgat 1800

 caactgaaaa accaaataca ggagccatgc aagaagtttg ccattgcaga 1850

 tgcaaccaga gaagatccat ttaaagagaa acttctagaa ataatgacaa 1900

 ggattcaaac ttattgtcaa atgagtccaa tgtcagattt tggaactcaa 1950

 ccctatgaac aatgggccat tcaaatggaa aaaaaagctg caaaagaagg 2000

 aaatcgcaaa gaacgtgttt gtgcagaaca tttgaggaag tacaatgagg 2050

 ccctacaaat taatgacaca attcgaatga tagatgcgta tactcatctt 2100

 gaaactttct ataatgaaga gaaagataag aagtttgcag tcatagaaga 2150

 tgatagtgat gagggtggtg atgatgagta ttgtgatggt gatgaagatg 2200

 aggatgattt aaagaaacct ttgaaactgg atgaaacaga tagatttctc 2250

 atgactttat tttttgaaaa caataaaatg ttgaaaaggc tggctgaaaa 2300

 cccagaatat gaaaatgaaa agctgaccaa attaagaaat accataatgg 2350

 agcaatatac taggactgag gaatcagcac gaggaataat ctttacaaaa 2400

 acacgacaga gtgcatatgc gctttcccag tggattactg aaaatgaaaa 2450

 atttgctgaa gtaggagtca aagcccacca tctgattgga gctggacaca 2500

 gcagtgagtt caaacccatg acacagaatg aacaaaaaga agtcattagt 2550

 aaatttcgca ctggaaaaat aaatctgctt atcgctacca cagtggcaga 2600

 agaaggtctg gatattaaag aatgtaacat tgttatccgt tatggtctcg 2650

 tcaccaatga aatagccatg gtccaggccc gtggtcgagc cagagctgat 2700

 gagagcacct acgtcctggt tgctcacagt ggttcaggag ttatcgaaca 2750

 tgagacagtt aatgatttcc gagagaagat gatgtataaa gctatacatt 2800

 gtgttcaaaa tatgaaacca gaggagtatg ctcataagat tttggaatta 2850

 cagatgcaaa gtataatgga aaagaaaatg aaaaccaaga gaaatattgc 2900

 caagcattac aagaataacc catcactaat aactttcctt tgcaaaaact 2950

 gcagtgtgct agcctgttct ggggaagata tccatgtaat tgagaaaatg 3000

 catcacgtca atatgacccc agaattcaag gaactttaca ttgtaagaga 3050

 aaacaaagca ctgcaaaaga agtgtgccga ctatcaaata aatggtgaaa 3100

 tcatctgcaa atgtggccag gcttggggaa caatgatggt gcacaaaggc 3150

 ttagatttgc cttgtctcaa aataaggaat tttgtagtgg ttttcaaaaa 3200

 taattcaaca aagaaacaat acaaaaagtg ggtagaatta cctatcacat 3250

 ttcccaatct tgactattca gaatgctgtt tatttagtga tgaggattag 3300

 cacttgattg aagattcttt taaaatacta tcagttaaac atttaatatg 3350

 attatgatta atgtattcat tatgctacag aactgacata agaatcaata 3400

 aaatgattgt tttactctgc aaaaaaaaaa aaaa 3434

<210> 3370
<211> 1025
<212> PRT
<213> Homo sapien

<400> 3370
 Met Ser Asn Gly Tyr Ser Thr Asp Glu Asn Phe Arg Tyr Leu Ile
   1               5                  10                  15

 Ser Cys Phe Arg Ala Arg Val Lys Met Tyr Ile Gln Val Glu Pro
                  20                  25                  30

 Val Leu Asp Tyr Leu Thr Phe Leu Pro Ala Glu Val Lys Glu Gln
                  35                  40                  45

 Ile Gln Arg Thr Val Ala Thr Ser Gly Asn Met Gln Ala Val Glu
                  50                  55                  60

 Leu Leu Leu Ser Thr Leu Glu Lys Gly Val Trp His Leu Gly Trp
                  65                  70                  75

 Thr Arg Glu Phe Val Glu Ala Leu Arg Arg Thr Gly Ser Pro Leu
                  80                  85                  90

 Ala Ala Arg Tyr Met Asn Pro Glu Leu Thr Asp Leu Pro Ser Pro
                  95                 100                 105

 Ser Phe Glu Asn Ala His Asp Glu Tyr Leu Gln Leu Leu Asn Leu
                 110                 115                 120

 Leu Gln Pro Thr Leu Val Asp Lys Leu Leu Val Arg Asp Val Leu
                 125                 130                 135

 Asp Lys Cys Met Glu Glu Glu Leu Leu Thr Ile Glu Asp Arg Asn
                 140                 145                 150

 Arg Ile Ala Ala Ala Glu Asn Asn Gly Asn Glu Ser Gly Val Arg
                 155                 160                 165

 Glu Leu Leu Lys Arg Ile Val Gln Lys Glu Asn Trp Phe Ser Ala
                 170                 175                 180

 Phe Leu Asn Val Leu Arg Gln Thr Gly Asn Asn Glu Leu Val Gln
                 185                 190                 195

 Glu Leu Thr Gly Ser Asp Cys Ser Glu Ser Asn Ala Glu Ile Glu
                 200                 205                 210

 Asn Leu Ser Gln Val Asp Gly Pro Gln Val Glu Glu Gln Leu Leu
                 215                 220                 225

 Ser Thr Thr Val Gln Pro Asn Leu Glu Lys Glu Val Trp Gly Met
                 230                 235                 240

 Glu Asn Asn Ser Ser Glu Ser Ser Phe Ala Asp Ser Ser Val Val
                 245                 250                 255

 Ser Glu Ser Asp Thr Ser Leu Ala Glu Gly Ser Val Ser Cys Leu
                 260                 265                 270

 Asp Glu Ser Leu Gly His Asn Ser Asn Met Gly Ser Asp Ser Gly
                 275                 280                 285

 Thr Met Gly Ser Asp Ser Asp Glu Glu Asn Val Ala Ala Arg Ala
                 290                 295                 300

 Ser Pro Glu Pro Glu Leu Gln Leu Arg Pro Tyr Gln Met Glu Val
                 305                 310                 315

 Ala Gln Pro Ala Leu Glu Gly Lys Asn Ile Ile Ile Cys Leu Pro
                 320                 325                 330

 Thr Gly Ser Gly Lys Thr Arg Val Ala Val Tyr Ile Ala Lys Asp
                 335                 340                 345

 His Leu Asp Lys Lys Lys Lys Ala Ser Glu Pro Gly Lys Val Ile
                 350                 355                 360

 Val Leu Val Asn Lys Val Leu Leu Val Glu Gln Leu Phe Arg Lys
                 365                 370                 375

 Glu Phe Gln Pro Phe Leu Lys Lys Trp Tyr Arg Val Ile Gly Leu
                 380                 385                 390

 Ser Gly Asp Thr Gln Leu Lys Ile Ser Phe Pro Glu Val Val Lys
                 395                 400                 405

 Ser Cys Asp Ile Ile Ile Ser Thr Ala Gln Ile Leu Glu Asn Ser
                 410                 415                 420

 Leu Leu Asn Leu Glu Asn Gly Glu Asp Ala Gly Val Gln Leu Ser
                 425                 430                 435

 Asp Phe Ser Leu Ile Ile Ile Asp Glu Cys His His Thr Asn Lys
                 440                 445                 450

 Glu Ala Val Tyr Asn Asn Ile Met Arg His Tyr Leu Met Gln Lys
                 455                 460                 465

 Leu Lys Asn Asn Arg Leu Lys Lys Glu Asn Lys Pro Val Ile Pro
                 470                 475                 480

 Leu Pro Gln Ile Leu Gly Leu Thr Ala Ser Pro Gly Val Gly Gly
                 485                 490                 495

 Ala Thr Lys Gln Ala Lys Ala Glu Glu His Ile Leu Lys Leu Cys
                 500                 505                 510

 Ala Asn Leu Asp Ala Phe Thr Ile Lys Thr Val Lys Glu Asn Leu
                 515                 520                 525

 Asp Gln Leu Lys Asn Gln Ile Gln Glu Pro Cys Lys Lys Phe Ala
                 530                 535                 540

 Ile Ala Asp Ala Thr Arg Glu Asp Pro Phe Lys Glu Lys Leu Leu
                 545                 550                 555

 Glu Ile Met Thr Arg Ile Gln Thr Tyr Cys Gln Met Ser Pro Met
                 560                 565                 570

 Ser Asp Phe Gly Thr Gln Pro Tyr Glu Gln Trp Ala Ile Gln Met
                 575                 580                 585

 Glu Lys Lys Ala Ala Lys Lys Gly Asn Arg Lys Glu Arg Val Cys
                 590                 595                 600

 Ala Glu His Leu Arg Lys Tyr Asn Glu Ala Leu Gln Ile Asn Asp
                 605                 610                 615

 Thr Ile Arg Met Ile Asp Ala Tyr Thr His Leu Glu Thr Phe Tyr
                 620                 625                 630

 Asn Glu Glu Lys Asp Lys Lys Phe Ala Val Ile Glu Asp Asp Ser
                 635                 640                 645

 Asp Glu Gly Gly Asp Asp Glu Tyr Cys Asp Gly Asp Glu Asp Glu
                 650                 655                 660

 Asp Asp Leu Lys Lys Pro Leu Lys Leu Asp Glu Thr Asp Arg Phe
                 665                 670                 675

 Leu Met Thr Leu Phe Phe Glu Asn Asn Lys Met Leu Lys Arg Leu
                 680                 685                 690

 Ala Glu Asn Pro Glu Tyr Glu Asn Glu Lys Leu Thr Lys Leu Arg
                 695                 700                 705

 Asn Thr Ile Met Glu Gln Tyr Thr Arg Thr Glu Glu Ser Ala Arg
                 710                 715                 720

 Gly Ile Ile Phe Thr Lys Thr Arg Gln Ser Ala Tyr Ala Leu Ser
                 725                 730                 735

 Gln Trp Ile Thr Glu Asn Glu Lys Phe Ala Glu Val Gly Val Lys
                 740                 745                 750

 Ala His His Leu Ile Gly Ala Gly His Ser Ser Glu Phe Lys Pro
                 755                 760                 765

 Met Thr Gln Asn Glu Gln Lys Glu Val Ile Ser Lys Phe Arg Thr
                 770                 775                 780

 Gly Lys Ile Asn Leu Leu Ile Ala Thr Thr Val Ala Glu Glu Gly
                 785                 790                 795

 Leu Asp Ile Lys Glu Cys Asn Ile Val Ile Arg Tyr Gly Leu Val
                 800                 805                 810

 Thr Asn Glu Ile Ala Met Val Gln Ala Arg Gly Arg Ala Arg Ala
                 815                 820                 825

 Asp Glu Ser Thr Tyr Val Leu Val Ala His Ser Gly Ser Gly Val
                 830                 835                 840

 Ile Glu His Glu Thr Val Asn Asp Phe Arg Glu Lys Met Met Tyr
                 845                 850                 855

 Lys Ala Ile His Cys Val Gln Asn Met Lys Pro Glu Glu Tyr Ala
                 860                 865                 870

 His Lys Ile Leu Glu Leu Gln Met Gln Ser Ile Met Glu Lys Lys
                 875                 880                 885

 Met Lys Thr Lys Arg Asn Ile Ala Lys His Tyr Lys Asn Asn Pro
                 890                 895                 900

 Ser Leu Ile Thr Phe Leu Cys Lys Asn Cys Ser Val Leu Ala Cys
                 905                 910                 915

 Ser Gly Glu Asp Ile His Val Ile Glu Lys Met His His Val Asn
                 920                 925                 930

 Met Thr Pro Glu Phe Lys Glu Leu Tyr Ile Val Arg Glu Asn Lys
                 935                 940                 945

 Ala Leu Gln Lys Lys Cys Ala Asp Tyr Gln Ile Asn Gly Glu Ile
                 950                 955                 960

 Ile Cys Lys Cys Gly Gln Ala Trp Gly Thr Met Met Val His Lys
                 965                 970                 975

 Gly Leu Asp Leu Pro Cys Leu Lys Ile Arg Asn Phe Val Val Val
                 980                 985                 990

 Phe Lys Asn Asn Ser Thr Lys Lys Gln Tyr Lys Lys Trp Val Glu
                 995                1000                1005

 Leu Pro Ile Thr Phe Pro Asn Leu Asp Tyr Ser Glu Cys Cys Leu
                1010                1015                1020

 Phe Ser Asp Glu Asp
                1025

<210> 3371
<211> 1265
<212> DNA
<213> Homo sapien

<400> 3371
 attggcgggc acgccccctc gcccgcggcc ccctccccgc ctctctccac 50

 cgcctcctct ggctccccgg tcagagggcc ggagcgagaa gatggcgaag 100

 acgtacgatt atctcttcaa gctcctgctg atcggcgact cgggggtagg 150

 caagacctgc ctcctgttcc gcttctcaga ggacgccttc aacaccacct 200

 tcatctccac catcggaatt gattttaaaa ttagaacgat agaactagat 250

 ggaaagaaaa ttaagcttca gatatgggac acagcgggtc aggaaagatt 300

 ccgaacaatc acgacagcgt actacagagg agccatgggc attatgctgg 350

 tctatgacat cacaaatgaa aaatcctttg acaatattaa aaattggatc 400

 agaaacattg aagagcatgc ctcttccgat gtcgaaagaa tgatcctggg 450

 taacaaatgt gatatgaatg acaaaagaca agtgtcaaaa gaaagagggg 500

 agaagctagc aattgactat gggattaaat tcttggagac aagcgcaaaa 550

 tccagtgcaa atgtagaaga ggcatttttt acacttgcac gagatataat 600

 gacaaaactc aacagaaaaa tgaatgacag caattcagca ggagcaggtg 650

 gaccagtgaa aataacagaa aaccgatcaa agaagaccag tttctttcgt 700

 tgctcgctac tttgatgaac tctttctgag agactgcagc acacctagag 750

 ggccctttcc tgcttctctg aaagcacagg tcacccagcc tcagaatcac 800

 acctcccggc tgctgctgag agcaccactg aacttagacc tctcaacaca 850

 gtatgccaag tggattccag cctcatggcc tagcaaaaga acagactccc 900

 tttttcaaac atggaagcaa tgaagtggag acacatgcag gacctaactc 950

 gttttttcct tgttttatta cctgttgcag aagcggttat ctttcttttt 1000

 tactttgcac atcagtgtta gcctttccct atttcagcac aatcttagac 1050

 tcatatttgc acacttttgt gtcgtgaagt tctagacaaa tttgtacatg 1100

 tggcaatgtt aaaagagcat ttacagcaga ggttaatata ctaaaattaa 1150

 agggtatttg gtctggttca tatggtcaaa tattactgcc ttggtagcat 1200

 ttatttaagg gctttttctt aaataagaat cattaaagtc attaaaaaat 1250

 ttactgaaat gccca 1265

<210> 3372
<211> 207
<212> PRT
<213> Homo sapien

<400> 3372
 Met Ala Lys Thr Tyr Asp Tyr Leu Phe Lys Leu Leu Leu Ile Gly
   1               5                  10                  15

 Asp Ser Gly Val Gly Lys Thr Cys Leu Leu Phe Arg Phe Ser Glu
                  20                  25                  30

 Asp Ala Phe Asn Thr Thr Phe Ile Ser Thr Ile Gly Ile Asp Phe
                  35                  40                  45

 Lys Ile Arg Thr Ile Glu Leu Asp Gly Lys Lys Ile Lys Leu Gln
                  50                  55                  60

 Ile Trp Asp Thr Ala Gly Gln Glu Arg Phe Arg Thr Ile Thr Thr
                  65                  70                  75

 Ala Tyr Tyr Arg Gly Ala Met Gly Ile Met Leu Val Tyr Asp Ile
                  80                  85                  90

 Thr Asn Glu Lys Ser Phe Asp Asn Ile Lys Asn Trp Ile Arg Asn
                  95                 100                 105

 Ile Glu Glu His Ala Ser Ser Asp Val Glu Arg Met Ile Leu Gly
                 110                 115                 120

 Asn Lys Cys Asp Met Asn Asp Lys Arg Gln Val Ser Lys Glu Arg
                 125                 130                 135

 Gly Glu Lys Leu Ala Ile Asp Tyr Gly Ile Lys Phe Leu Glu Thr
                 140                 145                 150

 Ser Ala Lys Ser Ser Ala Asn Val Glu Glu Ala Phe Phe Thr Leu
                 155                 160                 165

 Ala Arg Asp Ile Met Thr Lys Leu Asn Arg Lys Met Asn Asp Ser
                 170                 175                 180

 Asn Ser Ala Gly Ala Gly Gly Pro Val Lys Ile Thr Glu Asn Arg
                 185                 190                 195

 Ser Lys Lys Thr Ser Phe Phe Arg Cys Ser Leu Leu
                 200                 205

<210> 3373
<211> 1924
<212> DNA
<213> Homo sapien

<400> 3373
 cgcccgggca ggttagaatt cagcgaccgc ttaattctag gctcagtccc 50

 gacgtggaac tcagcagcgg aggctggacg cttgcatggc gcttgagaga 100

 ttccatcgtg cctggctcac ataagcgctt cctggaagtg aagtcgtgct 150

 gtcctgaacg cgggccaggc agctgcggcc tgggggtttt ggagtgatca 200

 cgaatgagca aggcgtttgg gctcctgagg caaatctgtc agtccatcct 250

 ggctgagtcc tcgcagtccc cggcagatct tgaagaaaag aaggaagaag 300

 acagcaacat gaagagagag cagcccagag agcgtcccag ggcctgggac 350

 taccctcatg gcctggttgg tttacacaac attggacaga cctgctgcct 400

 taactccttg attcaggtgt tcgtaatgaa tgtggacttc accaggatat 450

 tgaagaggat cacggtgccc aggggagctg acgagcagag gagaagcgtc 500

 cctttccaga tgcttctgct gctggagaag atgcaggaca gccggcagaa 550

 agcagtgcgg cccctggagc tggcctactg cctgcagaag tgcaacgtgc 600

 ccttgtttgt ccaacatgat gctgcccaac tgtacctcaa actctggaac 650

 ctgattaagg accagatcac tgatgtgcac ttggtggaga gactgcaggc 700

 cctgtatacg atccgggtga aggactcctt gatttgcgtt gactgtgcca 750

 tggagagtag cagaaacagc agcatgctca ccctcccact ttctcttttt 800

 gatgtggact caaagcccct gaagacactg gaggacgccc tgcactgctt 850

 cttccagccc agggagttat caagcaaaag caagtgcttc tgtgagaact 900

 gtgggaagaa gacccgtggg aaacaggtct tgaagctgac ccatttgccc 950

 cagaccctga caatccacct catgcgattc tccatcagga attcacagac 1000

 gagaaagatc tgccactccc tgtacttccc ccagagcttg gatttcagcc 1050

 agatccttcc aatgaagcga gagtcttgtg atgctgagga gcagtctgga 1100

 gggcagtatg agctttttgc tgtgattgcg cacgtgggaa tggcagactc 1150

 cggtcattac tgtgtctaca tccggaatgc tgtggatgga aaatggtctt 1200

 gcttcaatga ctccaatatt tgcttggtgt cctgggaaga catccagtgt 1250

 acctacggaa atcctaacta ccactggcag gaaactgcat atcttctggt 1300

 ttacatgaag atggagtgct aatggaaatg cccaaaacct tcagagattg 1350

 acacgctgtc attttccatt tccgttcctg gatctacgga gtcttctaag 1400

 agattttgca atgaggagaa gcattgtttt caaactatat aactgacctt 1450

 atttataatt agggatatta tcaaaatatg taaccatgag gcccctcagg 1500

 tcctgatcag tcagaatgga tgctttcacc agcagacccg gccatgtggc 1550

 tgctcggtcc tgggtgctcg ctgctgtgca agacattagc cctttagtta 1600

 tgagcctgtg ggaacttcag gggttcccag tggggagagc agtggcagtg 1650

 ggaggcatct gggggccaaa ggtcagtggc agggggtatt tcagtattat 1700

 acaactgctg tgaccagact tgtatactgg ctgaatatca gtgctgtttg 1750

 taatttttca ctttgagaac caacattaat tccatatgaa tcaagtgttt 1800

 tgtaactgct attcatttat tcagcaaata tttattgagc atctcttctc 1850

 cataagatag tgtgataaac acggtcatga ataaagttat tttccccgaa 1900

 aaaaaaaaaa aaaaaaaaaa aaaa 1924

<210> 3374
<211> 372
<212> PRT
<213> Homo sapien

<400> 3374
 Met Ser Lys Ala Phe Gly Leu Leu Arg Gln Ile Cys Gln Ser Ile
   1               5                  10                  15

 Leu Ala Glu Ser Ser Gln Ser Pro Ala Asp Leu Glu Glu Lys Lys
                  20                  25                  30

 Glu Glu Asp Ser Asn Met Lys Arg Glu Gln Pro Arg Glu Arg Pro
                  35                  40                  45

 Arg Ala Trp Asp Tyr Pro His Gly Leu Val Gly Leu His Asn Ile
                  50                  55                  60

 Gly Gln Thr Cys Cys Leu Asn Ser Leu Ile Gln Val Phe Val Met
                  65                  70                  75

 Asn Val Asp Phe Thr Arg Ile Leu Lys Arg Ile Thr Val Pro Arg
                  80                  85                  90

 Gly Ala Asp Glu Gln Arg Arg Ser Val Pro Phe Gln Met Leu Leu
                  95                 100                 105

 Leu Leu Glu Lys Met Gln Asp Ser Arg Gln Lys Ala Val Arg Pro
                 110                 115                 120

 Leu Glu Leu Ala Tyr Cys Leu Gln Lys Cys Asn Val Pro Leu Phe
                 125                 130                 135

 Val Gln His Asp Ala Ala Gln Leu Tyr Leu Lys Leu Trp Asn Leu
                 140                 145                 150

 Ile Lys Asp Gln Ile Thr Asp Val His Leu Val Glu Arg Leu Gln
                 155                 160                 165

 Ala Leu Tyr Thr Ile Arg Val Lys Asp Ser Leu Ile Cys Val Asp
                 170                 175                 180

 Cys Ala Met Glu Ser Ser Arg Asn Ser Ser Met Leu Thr Leu Pro
                 185                 190                 195

 Leu Ser Leu Phe Asp Val Asp Ser Lys Pro Leu Lys Thr Leu Glu
                 200                 205                 210

 Asp Ala Leu His Cys Phe Phe Gln Pro Arg Glu Leu Ser Ser Lys
                 215                 220                 225

 Ser Lys Cys Phe Cys Glu Asn Cys Gly Lys Lys Thr Arg Gly Lys
                 230                 235                 240

 Gln Val Leu Lys Leu Thr His Leu Pro Gln Thr Leu Thr Ile His
                 245                 250                 255

 Leu Met Arg Phe Ser Ile Arg Asn Ser Gln Thr Arg Lys Ile Cys
                 260                 265                 270

 His Ser Leu Tyr Phe Pro Gln Ser Leu Asp Phe Ser Gln Ile Leu
                 275                 280                 285

 Pro Met Lys Arg Glu Ser Cys Asp Ala Glu Glu Gln Ser Gly Gly
                 290                 295                 300

 Gln Tyr Glu Leu Phe Ala Val Ile Ala His Val Gly Met Ala Asp
                 305                 310                 315

 Ser Gly His Tyr Cys Val Tyr Ile Arg Asn Ala Val Asp Gly Lys
                 320                 325                 330

 Trp Ser Cys Phe Asn Asp Ser Asn Ile Cys Leu Val Ser Trp Glu
                 335                 340                 345

 Asp Ile Gln Cys Thr Tyr Gly Asn Pro Asn Tyr His Trp Gln Glu
                 350                 355                 360

 Thr Ala Tyr Leu Leu Val Tyr Met Lys Met Glu Cys
                 365                 370

<210> 3375
<211> 1719
<212> DNA
<213> Homo sapien

<400> 3375
 ggcacgaggc ttttattcaa ctgaggtgtc agtttcttcc actgaaaatg 50

 ctgtcagttc tgacctccgg gcaggggatg tacctgtttt atctttgagt 100

 aatagcagtg agaatgccgc ctctgtgatc agctacagtg gctctgcacc 150

 ctcggtcatt gtacacagca gccagttttc atcggtgatc atgcacagca 200

 atgccattgc tgccatgacc agcagcaacc acagagcctt ttcagaccca 250

 gctgtcagtc agtccctgaa agatgacagt aagcccgagc cagataaagt 300

 gggtaggttt gcaagcagac ccaaaagcat taaggagaaa aagaaaacta 350

 catcacatac caggggagaa ataccggagg agtcaaacta tgttgctgat 400

 cctggaggat cactgagcaa aaccacaaat attgctgaag aaaccagcaa 450

 aattgaaacc tacattgcaa aacctgctct gccgggaacc tccacaaata 500

 gtaatgttgc acccctttgc caaataacag tgaaaattgg aaacgaagcc 550

 attgtgaaaa ggcacattct aggatctaaa ttgttttata aaagagggag 600

 aagacccaag tatcagatgc aggaggagcc tttgccacag gggaatgacc 650

 cagaacccag tggagacagc ccactcgggc tttgccaatc cgagtgcatg 700

 gagatgagtg aagtgttcga tgacgcaagt gaccaggatt ccactgacaa 750

 accgtggcgc ccttactaca actacaaacc caaaaagaaa tccagacagt 800

 tgaaaaaaat gaggaaagtc aactggagga aggagcacgg aaacaggagc 850

 ccgagccata aatgtaaata cccagcagaa ctggattgcg ccgtggggaa 900

 ggctcctcag gataaaccct ttgaggaaga agaaactaaa gagatgccca 950

 agctgcagtg tgaactctgt gatggagaca aagcagtggg ggctggaaac 1000

 caaggaaggc cccaccgaca tcttacttct cggccatatg cctgcgagct 1050

 ctgcgccaag cagttccaga gcccttccac actcaaaatg cacatgagat 1100

 gtcacaccgg ggagaagcca taccagtgca agacctgcgg acggtgcttt 1150

 tcggtgcaag gaaacttaca gaaacatgaa cgcatccacc tgggcttgaa 1200

 ggagttcgtc tgtcagtatt gcaacaaggc attcaccttg aatgagaccc 1250

 tcaaaatcca tgaaagaatc catactggag aaaagcgtta ccactgtcag 1300

 ttctgctttc agagattttt gtatctctcc accaaaagga atcacgagca 1350

 gaggcatatt cgggagcata atgggaaggg ctatgcctgc ttccagtgcc 1400

 ccaaaatttg caaaacagct gctgcccttg gaatgcacca aaagaaacac 1450

 ttattcaaaa gcccaagtca gcaggagaaa ataggtgacg tgtgccacga 1500

 aaactcaaat cccttggaga atcaacattt cattggttca gaagacaatg 1550

 accaaaagga taacatacaa accggtgtgg aaaatgttgt cctttgagtg 1600

 gcaagaatta gaaaaatctt caaaaatata gttggtggtt ttttttagtt 1650

 atgatttaag tttagtttca ttttgtccat gtgacagtca tgaaggagtg 1700

 aaaaaaaaaa aaaaaaaaa 1719

<210> 3376
<211> 326
<212> PRT
<213> Homo sapien

<400> 3376
 Met Gln Glu Glu Pro Leu Pro Gln Gly Asn Asp Pro Glu Pro Ser
   1               5                  10                  15

 Gly Asp Ser Pro Leu Gly Leu Cys Gln Ser Glu Cys Met Glu Met
                  20                  25                  30

 Ser Glu Val Phe Asp Asp Ala Ser Asp Gln Asp Ser Thr Asp Lys
                  35                  40                  45

 Pro Trp Arg Pro Tyr Tyr Asn Tyr Lys Pro Lys Lys Lys Ser Arg
                  50                  55                  60

 Gln Leu Lys Lys Met Arg Lys Val Asn Trp Arg Lys Glu His Gly
                  65                  70                  75

 Asn Arg Ser Pro Ser His Lys Cys Lys Tyr Pro Ala Glu Leu Asp
                  80                  85                  90

 Cys Ala Val Gly Lys Ala Pro Gln Asp Lys Pro Phe Glu Glu Glu
                  95                 100                 105

 Glu Thr Lys Glu Met Pro Lys Leu Gln Cys Glu Leu Cys Asp Gly
                 110                 115                 120

 Asp Lys Ala Val Gly Ala Gly Asn Gln Gly Arg Pro His Arg His
                 125                 130                 135

 Leu Thr Ser Arg Pro Tyr Ala Cys Glu Leu Cys Ala Lys Gln Phe
                 140                 145                 150

 Gln Ser Pro Ser Thr Leu Lys Met His Met Arg Cys His Thr Gly
                 155                 160                 165

 Glu Lys Pro Tyr Gln Cys Lys Thr Cys Gly Arg Cys Phe Ser Val
                 170                 175                 180

 Gln Gly Asn Leu Gln Lys His Glu Arg Ile His Leu Gly Leu Lys
                 185                 190                 195

 Glu Phe Val Cys Gln Tyr Cys Asn Lys Ala Phe Thr Leu Asn Glu
                 200                 205                 210

 Thr Leu Lys Ile His Glu Arg Ile His Thr Gly Glu Lys Arg Tyr
                 215                 220                 225

 His Cys Gln Phe Cys Phe Gln Arg Phe Leu Tyr Leu Ser Thr Lys
                 230                 235                 240

 Arg Asn His Glu Gln Arg His Ile Arg Glu His Asn Gly Lys Gly
                 245                 250                 255

 Tyr Ala Cys Phe Gln Cys Pro Lys Ile Cys Lys Thr Ala Ala Ala
                 260                 265                 270

 Leu Gly Met His Gln Lys Lys His Leu Phe Lys Ser Pro Ser Gln
                 275                 280                 285

 Gln Glu Lys Ile Gly Asp Val Cys His Glu Asn Ser Asn Pro Leu
                 290                 295                 300

 Glu Asn Gln His Phe Ile Gly Ser Glu Asp Asn Asp Gln Lys Asp
                 305                 310                 315

 Asn Ile Gln Thr Gly Val Glu Asn Val Val Leu
                 320                 325

<210> 3377
<211> 1196
<212> DNA
<213> Homo sapien

<400> 3377
 acctttgagc gatggcggcg tctggggaac cccagaggca gtggcaagag 50

 gaggtggcgg cggtggtagt ggtgggctcc tgcatgaccg acctggtcag 100

 tcttacttct cgtttgccaa aaactggaga aaccatccat ggacataagt 150

 tttttattgg ctttggaggg aaaggtgcca accagtgtgt ccaagctgct 200

 cggcttggag caatgacgtc catggtgtgt aaggttggca aagattcttt 250

 tggcaatgat tatatagaaa acttaaaaca gaatgatatt tctacagaat 300

 ttacatatca gactaaagat gctgctacag gaactgcttc tataattgtc 350

 aataatgaag gccagaatat cattgtcata gtggctggag caaatttact 400

 tttgaatacg gaggatctga gggcagcagc caatgtcatt agcagagcca 450

 aagtcatggt ctgccagctc gaaataactc cagcaacttc tttggaagcc 500

 ctaacaatgg cccgcaggag tggagtgaaa accttgttca atccagcccc 550

 tgccattgct gacctggatc cccagttcta caccctctca gatgtgttct 600

 gctgcaatga aagtgaggct gagattttaa ctggcctcac ggtgggcagc 650

 gctgcagatg ctggggaggc tgcattagtg ctcttgaaaa ggggctgcca 700

 ggtggtaatc attaccttag gggctgaagg atgtgtggtg ctgtcacaga 750

 cagaacctga gccaaagcac attcccacag agaaagtcaa ggctgtggat 800

 accacgggtg ctggtgacag ctttgtggga gctctggcct tctacctggc 850

 ttactatcca aatctgtcct tggaagacat gctcaacaga tccaatttca 900

 ttgcagcagt cagtgtccag gctgcaggaa cacagtcatc ttacccttac 950

 aaaaaagacc ttccgcttac tctgttttga ttgctattag tcccaaaata 1000

 aatatacctg ggaataaaat gtacttgggg gtggctgctc ctggctaatg 1050

 cttattagaa aatgtcctcg tcccctttct ttgcaaatat tagttctttt 1100

 acgaagtcat cctcaagctt caatttattt ataacgatga ttcttttgct 1150

 ttccatgcat ttgcacaaaa caaccagaat taaagattcc acaacc 1196

<210> 3378
<211> 322
<212> PRT
<213> Homo sapien

<400> 3378
 Met Ala Ala Ser Gly Glu Pro Gln Arg Gln Trp Gln Glu Glu Val
   1               5                  10                  15

 Ala Ala Val Val Val Val Gly Ser Cys Met Thr Asp Leu Val Ser
                  20                  25                  30

 Leu Thr Ser Arg Leu Pro Lys Thr Gly Glu Thr Ile His Gly His
                  35                  40                  45

 Lys Phe Phe Ile Gly Phe Gly Gly Lys Gly Ala Asn Gln Cys Val
                  50                  55                  60

 Gln Ala Ala Arg Leu Gly Ala Met Thr Ser Met Val Cys Lys Val
                  65                  70                  75

 Gly Lys Asp Ser Phe Gly Asn Asp Tyr Ile Glu Asn Leu Lys Gln
                  80                  85                  90

 Asn Asp Ile Ser Thr Glu Phe Thr Tyr Gln Thr Lys Asp Ala Ala
                  95                 100                 105

 Thr Gly Thr Ala Ser Ile Ile Val Asn Asn Glu Gly Gln Asn Ile
                 110                 115                 120

 Ile Val Ile Val Ala Gly Ala Asn Leu Leu Leu Asn Thr Glu Asp
                 125                 130                 135

 Leu Arg Ala Ala Ala Asn Val Ile Ser Arg Ala Lys Val Met Val
                 140                 145                 150

 Cys Gln Leu Glu Ile Thr Pro Ala Thr Ser Leu Glu Ala Leu Thr
                 155                 160                 165

 Met Ala Arg Arg Ser Gly Val Lys Thr Leu Phe Asn Pro Ala Pro
                 170                 175                 180

 Ala Ile Ala Asp Leu Asp Pro Gln Phe Tyr Thr Leu Ser Asp Val
                 185                 190                 195

 Phe Cys Cys Asn Glu Ser Glu Ala Glu Ile Leu Thr Gly Leu Thr
                 200                 205                 210

 Val Gly Ser Ala Ala Asp Ala Gly Glu Ala Ala Leu Val Leu Leu
                 215                 220                 225

 Lys Arg Gly Cys Gln Val Val Ile Ile Thr Leu Gly Ala Glu Gly
                 230                 235                 240

 Cys Val Val Leu Ser Gln Thr Glu Pro Glu Pro Lys His Ile Pro
                 245                 250                 255

 Thr Glu Lys Val Lys Ala Val Asp Thr Thr Gly Ala Gly Asp Ser
                 260                 265                 270

 Phe Val Gly Ala Leu Ala Phe Tyr Leu Ala Tyr Tyr Pro Asn Leu
                 275                 280                 285

 Ser Leu Glu Asp Met Leu Asn Arg Ser Asn Phe Ile Ala Ala Val
                 290                 295                 300

 Ser Val Gln Ala Ala Gly Thr Gln Ser Ser Tyr Pro Tyr Lys Lys
                 305                 310                 315

 Asp Leu Pro Leu Thr Leu Phe
                 320

<210> 3379
<211> 2740
<212> DNA
<213> Homo sapien

<400> 3379
 ggcggcggcg gcggcggcga agaactgttc cttccacctc ttcagccccg 50

 gcaggacggg ggcggccgcc gcgaacccgg ggcggggaca gcacgcagcc 100

 tcgaggcgcg cacccccgcc cggcagcggc cccgacaccc ggggcgagcg 150

 ggaaaacggc aacggcggcg gcggcggcgg cggcggggga aggatgcagg 200

 ggaagaagcc gggcggttcg tcgggcggcg gccggagcgg cgagctgcag 250

 ggggacgagg cgcagaggaa caagaaaaag aaaaagaagg tgtcctgctt 300

 ttccaacatc aagatcttcc tggtgtccga gtgcgccctg atgctggcgc 350

 agggcacggt gggcgcctac ctggtgagcg tcctgaccac cctggagcgt 400

 aggttcaacc tgcagagcgc tgacgtgggt gtgatcgcta gcagcttcga 450

 gatcgggaac ctggcgctca tcctcttcgt gagctacttc ggggcacgcg 500

 ggcaccggcc gcgcctgatc ggctgcggcg gcatcgtcat ggcgctgggc 550

 gcgctgctgt cggcgctgcc cgagttcctg acccaccagt acaagtacga 600

 ggcgggcgag atccgctggg gcgccgaggg ccgcgacgtc tgcgcagcca 650

 acggctcggg cggcgacgag gggcccgacc ccgacctcat ctgccgcaac 700

 cggacggcta ccaacatgat gtacttgctg ctcattgggg cccaggtgct 750

 cctgggcatc ggtgctaccc ctgtgcagcc cctgggcgtc tcctactacg 800

 acgaccacgt gcggaggaag gactcctcgc tctatatagg aatcctgttc 850

 acgatgctgg tatttggacc agcctgcggg tttatcctgg gctctttctg 900

 taccaaaatc tacgtggatg cggtcttcat tgacacaagt aacctggaca 950

 tcactccgga cgacccccgc tggatcggag cctggtgggg tggctttctg 1000

 ctctgcggtg ccttactctt cttctcttcc ctcttgatgt ttgggtttcc 1050

 acagtccctg cccccgcact cagaccccgc catggaaagc gagcaggcca 1100

 tgctctccga aagagaatac gagagaccca agcccagcaa cggggtcctg 1150

 aggcaccccc tggagccaga cagcagtgcc tcctgtttcc agcagctgag 1200

 agtgatcccg aaggtcacca agcacctgct ctcaaaccct gtgttcacct 1250

 gcatcatcct ggccgcctgc atggagattg cagtggtggc tggcttcgct 1300

 gcctttttgg ggaagtacct ggagcagcag tttaacctca ccacctcttc 1350

 tgccaaccag ctgcttggga tgactgcgat cccgtgtgct tgtctgggta 1400

 tcttcctggg aggtcttttg gtgaagaagc tcagcctgtc tgccctgggg 1450

 gccattcgga tggccatgct cgtcaacctg gtgtccactg cttgctacgt 1500

 ctccttcctc ttcctgggct gcgacactgg ccctgtggct ggggttactg 1550

 ttccctatgg aaacagcaca gcacctggct cagccctgga cccctactcg 1600

 ccctgcaata ataactgtga atgccaaacc gattccttca ctccagtgtg 1650

 tggggcagat ggcatcacct acctgtctgc ctgctttgct ggctgcaaca 1700

 gcacgaatct cacgggctgt gcgtgcctca ccaccgtccc tgctgagaac 1750

 gcaaccgtgg ttcctggaaa atgccccagt cctgggtgcc aagaggcctt 1800

 cctcactttc ctctgtgtga tgtgtatctg cagcctgatc ggtgccatgg 1850

 cacagacacc ctcagtcatc atcctcatca ggacagtcag ccctgaactc 1900

 aagtcttacg ctttgggagt tctttttctc ctccttcgtt tgttgggctt 1950

 catccctcca cccctcatct tcggggctgg catcgactcc acctgcctgt 2000

 tctggagcac gttctgtggg gagcaaggcg cctgcgtcct ctacgacaat 2050

 gtggtctacc gatacctgta tgtcagcatc gccatcgcgc tcaaatcctt 2100

 cgccttcatc ctgtacacca ccacgtggca gtgcctgagg aaaaactata 2150

 aacgctacat caaaaaccac gagggcgggc tgagcaccag tgagttcttt 2200

 gcctctactc tgaccctaga caacctgggg agggaccctg tgcccgcaaa 2250

 ccagacacat aggacaaagt ttatctataa cctggaagac catgagtggt 2300

 gtgaaaacat ggagtccgtt ttatagtgac taaaggaggg ctgaactctg 2350

 tattagtaat ccaagggtca tttttttctt aaaaaaagaa aaaaaggttc 2400

 caaaaaaaac caaaactcag tacacacaca caggcacaga tgcacacaca 2450

 cgcagacaga cacaccgact ttgtcctttt tctcagcatc agagccagac 2500

 aggattcaga ataaggagag aatgacatcg tgcggcaggg tcctggaggc 2550

 cactcgcgcg gctgggccac agagtctact ttgaaggcac ctcatggttt 2600

 tcaggatgct gacagctgca agcaacaggc actgccaaat tcagggaaca 2650

 gtggtggcca gcttggagga tggacatttc tggatacaca tacacataca 2700

 aaacagaaaa cattttttaa aagaagtttc ctaaaataaa 2740

<210> 3380
<211> 710
<212> PRT
<213> Homo sapien

<400> 3380
 Met Gln Gly Lys Lys Pro Gly Gly Ser Ser Gly Gly Gly Arg Ser
   1               5                  10                  15

 Gly Glu Leu Gln Gly Asp Glu Ala Gln Arg Asn Lys Lys Lys Lys
                  20                  25                  30

 Lys Lys Val Ser Cys Phe Ser Asn Ile Lys Ile Phe Leu Val Ser
                  35                  40                  45

 Glu Cys Ala Leu Met Leu Ala Gln Gly Thr Val Gly Ala Tyr Leu
                  50                  55                  60

 Val Ser Val Leu Thr Thr Leu Glu Arg Arg Phe Asn Leu Gln Ser
                  65                  70                  75

 Ala Asp Val Gly Val Ile Ala Ser Ser Phe Glu Ile Gly Asn Leu
                  80                  85                  90

 Ala Leu Ile Leu Phe Val Ser Tyr Phe Gly Ala Arg Gly His Arg
                  95                 100                 105

 Pro Arg Leu Ile Gly Cys Gly Gly Ile Val Met Ala Leu Gly Ala
                 110                 115                 120

 Leu Leu Ser Ala Leu Pro Glu Phe Leu Thr His Gln Tyr Lys Tyr
                 125                 130                 135

 Glu Ala Gly Glu Ile Arg Trp Gly Ala Glu Gly Arg Asp Val Cys
                 140                 145                 150

 Ala Ala Asn Gly Ser Gly Gly Asp Glu Gly Pro Asp Pro Asp Leu
                 155                 160                 165

 Ile Cys Arg Asn Arg Thr Ala Thr Asn Met Met Tyr Leu Leu Leu
                 170                 175                 180

 Ile Gly Ala Gln Val Leu Leu Gly Ile Gly Ala Thr Pro Val Gln
                 185                 190                 195

 Pro Leu Gly Val Ser Tyr Tyr Asp Asp His Val Arg Arg Lys Asp
                 200                 205                 210

 Ser Ser Leu Tyr Ile Gly Ile Leu Phe Thr Met Leu Val Phe Gly
                 215                 220                 225

 Pro Ala Cys Gly Phe Ile Leu Gly Ser Phe Cys Thr Lys Ile Tyr
                 230                 235                 240

 Val Asp Ala Val Phe Ile Asp Thr Ser Asn Leu Asp Ile Thr Pro
                 245                 250                 255

 Asp Asp Pro Arg Trp Ile Gly Ala Trp Trp Gly Gly Phe Leu Leu
                 260                 265                 270

 Cys Gly Ala Leu Leu Phe Phe Ser Ser Leu Leu Met Phe Gly Phe
                 275                 280                 285

 Pro Gln Ser Leu Pro Pro His Ser Asp Pro Ala Met Glu Ser Glu
                 290                 295                 300

 Gln Ala Met Leu Ser Glu Arg Glu Tyr Glu Arg Pro Lys Pro Ser
                 305                 310                 315

 Asn Gly Val Leu Arg His Pro Leu Glu Pro Asp Ser Ser Ala Ser
                 320                 325                 330

 Cys Phe Gln Gln Leu Arg Val Ile Pro Lys Val Thr Lys His Leu
                 335                 340                 345

 Leu Ser Asn Pro Val Phe Thr Cys Ile Ile Leu Ala Ala Cys Met
                 350                 355                 360

 Glu Ile Ala Val Val Ala Gly Phe Ala Ala Phe Leu Gly Lys Tyr
                 365                 370                 375

 Leu Glu Gln Gln Phe Asn Leu Thr Thr Ser Ser Ala Asn Gln Leu
                 380                 385                 390

 Leu Gly Met Thr Ala Ile Pro Cys Ala Cys Leu Gly Ile Phe Leu
                 395                 400                 405

 Gly Gly Leu Leu Val Lys Lys Leu Ser Leu Ser Ala Leu Gly Ala
                 410                 415                 420

 Ile Arg Met Ala Met Leu Val Asn Leu Val Ser Thr Ala Cys Tyr
                 425                 430                 435

 Val Ser Phe Leu Phe Leu Gly Cys Asp Thr Gly Pro Val Ala Gly
                 440                 445                 450

 Val Thr Val Pro Tyr Gly Asn Ser Thr Ala Pro Gly Ser Ala Leu
                 455                 460                 465

 Asp Pro Tyr Ser Pro Cys Asn Asn Asn Cys Glu Cys Gln Thr Asp
                 470                 475                 480

 Ser Phe Thr Pro Val Cys Gly Ala Asp Gly Ile Thr Tyr Leu Ser
                 485                 490                 495

 Ala Cys Phe Ala Gly Cys Asn Ser Thr Asn Leu Thr Gly Cys Ala
                 500                 505                 510

 Cys Leu Thr Thr Val Pro Ala Glu Asn Ala Thr Val Val Pro Gly
                 515                 520                 525

 Lys Cys Pro Ser Pro Gly Cys Gln Glu Ala Phe Leu Thr Phe Leu
                 530                 535                 540

 Cys Val Met Cys Ile Cys Ser Leu Ile Gly Ala Met Ala Gln Thr
                 545                 550                 555

 Pro Ser Val Ile Ile Leu Ile Arg Thr Val Ser Pro Glu Leu Lys
                 560                 565                 570

 Ser Tyr Ala Leu Gly Val Leu Phe Leu Leu Leu Arg Leu Leu Gly
                 575                 580                 585

 Phe Ile Pro Pro Pro Leu Ile Phe Gly Ala Gly Ile Asp Ser Thr
                 590                 595                 600

 Cys Leu Phe Trp Ser Thr Phe Cys Gly Glu Gln Gly Ala Cys Val
                 605                 610                 615

 Leu Tyr Asp Asn Val Val Tyr Arg Tyr Leu Tyr Val Ser Ile Ala
                 620                 625                 630

 Ile Ala Leu Lys Ser Phe Ala Phe Ile Leu Tyr Thr Thr Thr Trp
                 635                 640                 645

 Gln Cys Leu Arg Lys Asn Tyr Lys Arg Tyr Ile Lys Asn His Glu
                 650                 655                 660

 Gly Gly Leu Ser Thr Ser Glu Phe Phe Ala Ser Thr Leu Thr Leu
                 665                 670                 675

 Asp Asn Leu Gly Arg Asp Pro Val Pro Ala Asn Gln Thr His Arg
                 680                 685                 690

 Thr Lys Phe Ile Tyr Asn Leu Glu Asp His Glu Trp Cys Glu Asn
                 695                 700                 705

 Met Glu Ser Val Leu
                 710

<210> 3381
<211> 2770
<212> DNA
<213> Homo sapien

<400> 3381
 gagtctggcc gcagtcgcgg cagtggtggc ttcccatccc caaaaggcgc 50

 cctccgactc cttgcgccgc actgctcgcc gggccagtcc ggaaacgggt 100

 cgtggagctc cgcaccactc ccgctggttc ccgaaggcag atcccttctc 150

 ccgagagttg cgagaaactt tcccttgtcc ccgacgctgc agcggctcgg 200

 gtaccgtggc agccgcaggt ttctgaaccc cgggccacgc tccccgcgcc 250

 tcggcttcgc gctcgtgtag atcgttccct ctctggttgc acgctgggga 300

 tcccggacct cgattctgcg ggcgagatgc ccctgggaca catcatgagg 350

 ctggacctgg agaaaattgc cctggagtac atcgtgccct gtctgcacga 400

 ggtgggcttc tgctacctgg acaacttcct gggcgaggtg gtgggcgact 450

 gcgtcctgga gcgcgtcaag cagctgcact gcaccggggc cctgcgggac 500

 ggccagctgg cggggccgcg cgccggcgtc tccaagcgac acctgcgggg 550

 cgaccagatc acgtggatcg ggggcaacga ggagggctgc gaggccatca 600

 gcttcctcct gtccctcatc gacaggctgg tcctctactg cgggagccgg 650

 ctgggcaaat actacgtcaa ggagaggtct aaggcaatgg tggcttgcta 700

 tccgggaaat ggaacaggtt atgttcgcca cgtggacaac cccaacggtg 750

 atggtcgctg catcacctgc atctactatc tgaacaagaa ttgggatgcc 800

 aagctacatg gtgggatcct gcggatattt ccagagggga aatcattcat 850

 agcagatgtg gagcccattt ttgacagact cctgttcttc tggtcagatc 900

 gtaggaaccc acacgaagtg cagccctctt acgcaaccag atatgctatg 950

 actgtctggt actttgatgc tgaagaaagg gcagaagcca aaaagaaatt 1000

 caggaattta actaggaaaa ctgaatctgc cctcactgaa gactgaccgt 1050

 gctctgaaat ctgctggcct tgttcatttt agtaacggtt cctgaattct 1100

 cttaaattct ttgagatcca aagatggcct cttcagtgac aacaatctcc 1150

 ctgctacttc ttgcatcctt cacatccctg tcttgtgtgt ggtacttcat 1200

 gttttcttgc caagactgtg ttgatcttca gatactctct ttgccagatg 1250

 aagttatttg ctaactccag aaattcctgc agacatccta ctcggccagc 1300

 ggtttacctg atagattcgg taatactatc aagagaagag cctaggagca 1350

 cagcgaggga atgaacctta cttgcacttt atgtatactt cctgatttga 1400

 aaggaggagg tttgaaaaga aaaaaatgga ggtggtagat gccacagaga 1450

 ggcatcacgg aagccttaac agcaggaaac agagaaattt gtgtcatctg 1500

 aacaatttcc agatgttctt aatccagggc tgttggggtt tctggagaat 1550

 tatcacaacc taatgacatt aatacctcta gaaagggctg ctgtcatagt 1600

 gaacaattta taagtgtccc atggggcaga cactcctttt ttcccagtcc 1650

 tgcaacctgg attttctgcc tcagctccat tttgctgaaa ataatgactt 1700

 tctgaataaa gatggcaaca caattttttc tccattttca gttcttacct 1750

 gggaacctaa ttccccagaa gctaaaaaac tagacattag ttgttttggt 1800

 tgctttgttg gaatggaatt taaatttaaa tgaaaggaaa aatatatccc 1850

 tggtagtttt gtgttaacca ctgataactg tggaaagagc taggtctact 1900

 gatatacaat aaacatgtgt gcatcttgaa caatttgaga ggggaggtgg 1950

 agttggaaat gtgggtgttc ctgttttttt tttttttttt tttttttttt 2000

 agttttcctt tttaatgagc tcacccttta acacaaaaaa agcagggtga 2050

 tgtattttaa aaaaggaagt ggaaataaaa aaatctcaaa gctatttgag 2100

 ttctcgtctg tccctagcag tctttcttca gctcacttgg ctctctagat 2150

 ccactgtggt tggcagtatg accagaatca tggaacttgc tagaactgtg 2200

 gaagcttcta ctcctgcagt aagcacagat cgcactgcct caataacttg 2250

 gtattgagca cgtattttgc aaaagctact tttcctagtt ttcagtatta 2300

 ctttcatgtt ttaaaaatcc ctttaatttc ttgcttgaaa atcccatgaa 2350

 cattaaagag ccagaaatat tttcctttgt tatgtacgga tatatatata 2400

 tatatagtct tccaagatag aagtttactt tttcctcttc tggttttgga 2450

 aaatttccag ataagacatg tcaccattaa ttctcaacga ctgctctatt 2500

 ttgttgtacg gtaatagtta tcaccttcta aattactatg taatttactc 2550

 acttattatg tttattgtct tgtatccttt ctctggagtg taagcacaat 2600

 gaagacagga attttgtata tttttaacca atgcaacata ctctcagcac 2650

 ctaaaatagt gccgggaaca tagtaagggc tcagtaaata cttgttgaat 2700

 aaactcagtc tcctacatta gcattctaaa aaaaaaaaaa aaaaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaag 2770

<210> 3382
<211> 239
<212> PRT
<213> Homo sapien

<400> 3382
 Met Pro Leu Gly His Ile Met Arg Leu Asp Leu Glu Lys Ile Ala
   1               5                  10                  15

 Leu Glu Tyr Ile Val Pro Cys Leu His Glu Val Gly Phe Cys Tyr
                  20                  25                  30

 Leu Asp Asn Phe Leu Gly Glu Val Val Gly Asp Cys Val Leu Glu
                  35                  40                  45

 Arg Val Lys Gln Leu His Cys Thr Gly Ala Leu Arg Asp Gly Gln
                  50                  55                  60

 Leu Ala Gly Pro Arg Ala Gly Val Ser Lys Arg His Leu Arg Gly
                  65                  70                  75

 Asp Gln Ile Thr Trp Ile Gly Gly Asn Glu Glu Gly Cys Glu Ala
                  80                  85                  90

 Ile Ser Phe Leu Leu Ser Leu Ile Asp Arg Leu Val Leu Tyr Cys
                  95                 100                 105

 Gly Ser Arg Leu Gly Lys Tyr Tyr Val Lys Glu Arg Ser Lys Ala
                 110                 115                 120

 Met Val Ala Cys Tyr Pro Gly Asn Gly Thr Gly Tyr Val Arg His
                 125                 130                 135

 Val Asp Asn Pro Asn Gly Asp Gly Arg Cys Ile Thr Cys Ile Tyr
                 140                 145                 150

 Tyr Leu Asn Lys Asn Trp Asp Ala Lys Leu His Gly Gly Ile Leu
                 155                 160                 165

 Arg Ile Phe Pro Glu Gly Lys Ser Phe Ile Ala Asp Val Glu Pro
                 170                 175                 180

 Ile Phe Asp Arg Leu Leu Phe Phe Trp Ser Asp Arg Arg Asn Pro
                 185                 190                 195

 His Glu Val Gln Pro Ser Tyr Ala Thr Arg Tyr Ala Met Thr Val
                 200                 205                 210

 Trp Tyr Phe Asp Ala Glu Glu Arg Ala Glu Ala Lys Lys Lys Phe
                 215                 220                 225

 Arg Asn Leu Thr Arg Lys Thr Glu Ser Ala Leu Thr Glu Asp
                 230                 235

<210> 3383
<211> 1983
<212> DNA
<213> Homo sapien

<400> 3383
 gtttctcaac atcctggctt agtattgtgt gcaaaatcag agaggggtgc 50

 aagatcctga tttttcagga gttcaagcga caatggcagc ccaatacggc 100

 agtatgagct tcaaccccag cacaccaggg gccagttatg ggcctggaag 150

 gcaagagccc agaaattccc aattgagaat tgtgttagtg ggtaaaaccg 200

 gagcaggaaa aagtgcaaca ggaaacagca tccttggccg gaaagtgttt 250

 cattctggca ctgcagcaaa atccattacc aagaagtgtg agaaacgcag 300

 cagctcatgg aaggaaacag aacttgtcgt agttgacaca ccaggcattt 350

 tcgacacaga ggtgcccaat gctgaaacgt ccaaggagat tattcgctgc 400

 attcttctga cctccccagg gcctcatgct ctgcttctgg tggttccact 450

 gggccgttac actgaggaag agcacaaagc cacagagaag atcctgaaaa 500

 tgtttggaga gagggctaga agtttcatga ttctcatatt cacccggaaa 550

 gatgacttag gtgacaccaa tttgcatgac tacttaaggg aagctccaga 600

 agacattcaa gacttgatgg acattttcgg tgaccgctac tgtgcgttaa 650

 acaacaaggc aacaggcgct gagcaggagg cccagagggc acagttgctg 700

 ggcctgatcc agcgcgtggt gagggagaac aaggaaggct gctacactaa 750

 taggatgtac caaagggcgg aggaggagat ccagaagcaa acacaagcaa 800

 tgcaagaact ccacagagtg gagctggaga gagagaaagc gcggataaga 850

 gaggagtatg aagagaaaat cagaaagctg gaagataaag tggagcagga 900

 aaagagaaag aagcaaatgg agaagaaact agcagaacag gaggctcact 950

 atgctgtaag gcagcaaagg gcaagaacgg aagtggagag taaggatggg 1000

 atacttgaat taatcatgac agcgttacag attgcttcct ttattttgtt 1050

 acgtctgttc gcggaagatt aaacttaatg aaaatctgtt tgtattttct 1100

 gcatattctc tggcaacctt gccccatact tacttattta gcatagtcga 1150

 gtgctctagt ttctgtctct caggcactcg taactaagga ccaccattgg 1200

 ccattggtag atgtttgatt gacttaacaa gagagggaca aattttcaat 1250

 ttgtgaaact ccaaagcaga aagtattggt gcttgctacc ttgtgaattc 1300

 ttccttagac atgcagagaa aatgtatgca agagaccaaa aagatggctc 1350

 caagctatgt catgttacct gtaataaaat cttttcttct agattctttc 1400

 tatgttggca gataatctcc ccttgtagct tccactcact tattcttgca 1450

 ttcagagtca caatgatcat cttacccatg tggtttttga gaaagaaaga 1500

 tcaattcttt gtttgcagta ggtaatctta gagatggaga tgattgtaga 1550

 attattccta gatgagtgtc aatttattta attccattgt catataagga 1600

 gtcaaattgt ttcttatcat ttgttcattg aagaacagag acctgtctgg 1650

 aaaatcgatc tctacaaatt caattaaata atgatcccca aatgctgaaa 1700

 aagtgaaata cagcaattca acagataata gagcaatgtt tagtatattc 1750

 agctgtatct gtagaaactc tttgacgaac ctcaatttaa ccaatttgat 1800

 gaatacccag ttctcttctt ttctagagaa agatagttgc aacctcacct 1850

 ccctcactca acactttgaa tacttattgt ttggcaggtc atccacacac 1900

 ttctgccccc actgcattga attttttgct tatgttgttt ataataaaac 1950

 ttttcaatta tctcaaaaaa aaaaaaaaaa aaa 1983

<210> 3384
<211> 329
<212> PRT
<213> Homo sapien

<400> 3384
 Met Ala Ala Gln Tyr Gly Ser Met Ser Phe Asn Pro Ser Thr Pro
   1               5                  10                  15

 Gly Ala Ser Tyr Gly Pro Gly Arg Gln Glu Pro Arg Asn Ser Gln
                  20                  25                  30

 Leu Arg Ile Val Leu Val Gly Lys Thr Gly Ala Gly Lys Ser Ala
                  35                  40                  45

 Thr Gly Asn Ser Ile Leu Gly Arg Lys Val Phe His Ser Gly Thr
                  50                  55                  60

 Ala Ala Lys Ser Ile Thr Lys Lys Cys Glu Lys Arg Ser Ser Ser
                  65                  70                  75

 Trp Lys Glu Thr Glu Leu Val Val Val Asp Thr Pro Gly Ile Phe
                  80                  85                  90

 Asp Thr Glu Val Pro Asn Ala Glu Thr Ser Lys Glu Ile Ile Arg
                  95                 100                 105

 Cys Ile Leu Leu Thr Ser Pro Gly Pro His Ala Leu Leu Leu Val
                 110                 115                 120

 Val Pro Leu Gly Arg Tyr Thr Glu Glu Glu His Lys Ala Thr Glu
                 125                 130                 135

 Lys Ile Leu Lys Met Phe Gly Glu Arg Ala Arg Ser Phe Met Ile
                 140                 145                 150

 Leu Ile Phe Thr Arg Lys Asp Asp Leu Gly Asp Thr Asn Leu His
                 155                 160                 165

 Asp Tyr Leu Arg Glu Ala Pro Glu Asp Ile Gln Asp Leu Met Asp
                 170                 175                 180

 Ile Phe Gly Asp Arg Tyr Cys Ala Leu Asn Asn Lys Ala Thr Gly
                 185                 190                 195

 Ala Glu Gln Glu Ala Gln Arg Ala Gln Leu Leu Gly Leu Ile Gln
                 200                 205                 210

 Arg Val Val Arg Glu Asn Lys Glu Gly Cys Tyr Thr Asn Arg Met
                 215                 220                 225

 Tyr Gln Arg Ala Glu Glu Glu Ile Gln Lys Gln Thr Gln Ala Met
                 230                 235                 240

 Gln Glu Leu His Arg Val Glu Leu Glu Arg Glu Lys Ala Arg Ile
                 245                 250                 255

 Arg Glu Glu Tyr Glu Glu Lys Ile Arg Lys Leu Glu Asp Lys Val
                 260                 265                 270

 Glu Gln Glu Lys Arg Lys Lys Gln Met Glu Lys Lys Leu Ala Glu
                 275                 280                 285

 Gln Glu Ala His Tyr Ala Val Arg Gln Gln Arg Ala Arg Thr Glu
                 290                 295                 300

 Val Glu Ser Lys Asp Gly Ile Leu Glu Leu Ile Met Thr Ala Leu
                 305                 310                 315

 Gln Ile Ala Ser Phe Ile Leu Leu Arg Leu Phe Ala Glu Asp
                 320                 325

<210> 3385
<211> 2077
<212> DNA
<213> Homo sapien

<400> 3385
 agcgcagcgt gcgggtggcc tggatcccgc gcagtggccc ggcgatgtcg 50

 ctcgtgctgc taagcctggc cgcgctgtgc aggagcgccg taccccgaga 100

 gccgaccgtt caatgtggct ctgaaactgg gccatctcca gagtggatgc 150

 tacaacatga tctaatcccc ggagacttga gggacctccg agtagaacct 200

 gttacaacta gtgttgcaac aggggactat tcaattttga tgaatgtaag 250

 ctgggtactc cgggcagatg ccagcatccg cttgttgaag gccaccaaga 300

 tttgtgtgac gggcaaaagc aacttccagt cctacagctg tgtgaggtgc 350

 aattacacag aggccttcca gactcagacc agaccctctg gtggtaaatg 400

 gacattttcc tacatcggct tccctgtaga gctgaacaca gtctatttca 450

 ttggggccca taatattcct aatgcaaata tgaatgaaga tggcccttcc 500

 atgtctgtga atttcacctc accaggctgc ctagaccaca taatgaaata 550

 taaaaaaaag tgtgtcaagg ccggaagcct gtgggatccg aacatcactg 600

 cttgtaagaa gaatgaggag acagtagaag tgaacttcac aaccactccc 650

 ctgggaaaca gatacatggc tcttatccaa cacagcacta tcatcgggtt 700

 ttctcaggtg tttgagccac accagaagaa acaaacgcga gcttcagtgg 750

 tgattccagt gactggggat agtgaaggtg ctacggtgca gctgactcca 800

 tattttccta cttgtggcag cgactgcatc cgacataaag gaacagttgt 850

 gctctgccca caaacaggcg tccctttccc tctggataac aacaaaagca 900

 agccgggagg ctggctgcct ctcctcctgc tgtctctgct ggtggccaca 950

 tgggtgctgg tggcagggat ctatctaatg tggaggcacg aaaggatcaa 1000

 gaagacttcc ttttctacca ccacactact gccccccatt aaggttcttg 1050

 tggtttaccc atctgaaata tgtttccatc acacaatttg ttacttcact 1100

 gaatttcttc aaaaccattg cagaagtgag gtcatccttg aaaagtggca 1150

 gaaaaagaaa atagcagaga tgggtccagt gcagtggctt gccactcaaa 1200

 agaaggcagc agacaaagtc gtcttccttc tttccaatga cgtcaacagt 1250

 gtgtgcgatg gtacctgtgg caagagcgag ggcagtccca gtgagaactc 1300

 tcaagacctc ttcccccttg cctttaacct tttctgcagt gatctaagaa 1350

 gccagattca tctgcacaaa tacgtggtgg tctactttag agagattgat 1400

 acaaaagacg attacaatgc tctcagtgtc tgccccaagt accacctcat 1450

 gaaggatgcc actgctttct gtgcagaact tctccatgtc aagcagcagg 1500

 tgtcagcagg aaaaagatca caagcctgcc acgatggctg ctgctccttg 1550

 tagcccaccc atgagaagca agagacctta aaggcttcct atcccaccaa 1600

 ttacagggaa aaaacgtgtg atgatcctga agcttactat gcagcctaca 1650

 aacagcctta gtaattaaaa cattttatac caataaaatt ttcaaatatt 1700

 gctaactaat gtagcattaa ctaacgattg gaaactacat ttacaacttc 1750

 aaagctgttt tatacataga aatcaattac agttttaatt gaaaactata 1800

 accattttga taatgcaaca ataaagcatc ttcagccaaa catctagtct 1850

 tccatagacc atgcattgca gtgtacccag aactgtttag ctaatattct 1900

 atgtttaatt aatgaatact aactctaaga acccctcact gattcactca 1950

 atagcatctt aagtgaaaaa ccttctatta catgcaaaaa atcattgttt 2000

 ttaagataac aaaagtaggg aataaacaag ctgaacccac ttttaaaaaa 2050

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 2077

<210> 3386
<211> 502
<212> PRT
<213> Homo sapien

<400> 3386
 Met Ser Leu Val Leu Leu Ser Leu Ala Ala Leu Cys Arg Ser Ala
   1               5                  10                  15

 Val Pro Arg Glu Pro Thr Val Gln Cys Gly Ser Glu Thr Gly Pro
                  20                  25                  30

 Ser Pro Glu Trp Met Leu Gln His Asp Leu Ile Pro Gly Asp Leu
                  35                  40                  45

 Arg Asp Leu Arg Val Glu Pro Val Thr Thr Ser Val Ala Thr Gly
                  50                  55                  60

 Asp Tyr Ser Ile Leu Met Asn Val Ser Trp Val Leu Arg Ala Asp
                  65                  70                  75

 Ala Ser Ile Arg Leu Leu Lys Ala Thr Lys Ile Cys Val Thr Gly
                  80                  85                  90

 Lys Ser Asn Phe Gln Ser Tyr Ser Cys Val Arg Cys Asn Tyr Thr
                  95                 100                 105

 Glu Ala Phe Gln Thr Gln Thr Arg Pro Ser Gly Gly Lys Trp Thr
                 110                 115                 120

 Phe Ser Tyr Ile Gly Phe Pro Val Glu Leu Asn Thr Val Tyr Phe
                 125                 130                 135

 Ile Gly Ala His Asn Ile Pro Asn Ala Asn Met Asn Glu Asp Gly
                 140                 145                 150

 Pro Ser Met Ser Val Asn Phe Thr Ser Pro Gly Cys Leu Asp His
                 155                 160                 165

 Ile Met Lys Tyr Lys Lys Lys Cys Val Lys Ala Gly Ser Leu Trp
                 170                 175                 180

 Asp Pro Asn Ile Thr Ala Cys Lys Lys Asn Glu Glu Thr Val Glu
                 185                 190                 195

 Val Asn Phe Thr Thr Thr Pro Leu Gly Asn Arg Tyr Met Ala Leu
                 200                 205                 210

 Ile Gln His Ser Thr Ile Ile Gly Phe Ser Gln Val Phe Glu Pro
                 215                 220                 225

 His Gln Lys Lys Gln Thr Arg Ala Ser Val Val Ile Pro Val Thr
                 230                 235                 240

 Gly Asp Ser Glu Gly Ala Thr Val Gln Leu Thr Pro Tyr Phe Pro
                 245                 250                 255

 Thr Cys Gly Ser Asp Cys Ile Arg His Lys Gly Thr Val Val Leu
                 260                 265                 270

 Cys Pro Gln Thr Gly Val Pro Phe Pro Leu Asp Asn Asn Lys Ser
                 275                 280                 285

 Lys Pro Gly Gly Trp Leu Pro Leu Leu Leu Leu Ser Leu Leu Val
                 290                 295                 300

 Ala Thr Trp Val Leu Val Ala Gly Ile Tyr Leu Met Trp Arg His
                 305                 310                 315

 Glu Arg Ile Lys Lys Thr Ser Phe Ser Thr Thr Thr Leu Leu Pro
                 320                 325                 330

 Pro Ile Lys Val Leu Val Val Tyr Pro Ser Glu Ile Cys Phe His
                 335                 340                 345

 His Thr Ile Cys Tyr Phe Thr Glu Phe Leu Gln Asn His Cys Arg
                 350                 355                 360

 Ser Glu Val Ile Leu Glu Lys Trp Gln Lys Lys Lys Ile Ala Glu
                 365                 370                 375

 Met Gly Pro Val Gln Trp Leu Ala Thr Gln Lys Lys Ala Ala Asp
                 380                 385                 390

 Lys Val Val Phe Leu Leu Ser Asn Asp Val Asn Ser Val Cys Asp
                 395                 400                 405

 Gly Thr Cys Gly Lys Ser Glu Gly Ser Pro Ser Glu Asn Ser Gln
                 410                 415                 420

 Asp Leu Phe Pro Leu Ala Phe Asn Leu Phe Cys Ser Asp Leu Arg
                 425                 430                 435

 Ser Gln Ile His Leu His Lys Tyr Val Val Val Tyr Phe Arg Glu
                 440                 445                 450

 Ile Asp Thr Lys Asp Asp Tyr Asn Ala Leu Ser Val Cys Pro Lys
                 455                 460                 465

 Tyr His Leu Met Lys Asp Ala Thr Ala Phe Cys Ala Glu Leu Leu
                 470                 475                 480

 His Val Lys Gln Gln Val Ser Ala Gly Lys Arg Ser Gln Ala Cys
                 485                 490                 495

 His Asp Gly Cys Cys Ser Leu
                 500

<210> 3387
<211> 1077
<212> DNA
<213> Homo sapien

<400> 3387
 gtgttttctg cgtgagagga aaagatgcta gaaccacagg agaatggcgt 50

 gattgaccta ccagattatg agcatgtaga agatgaaact tttcctcctt 100

 tcccacctcc agcctctcca gagagacaag atggtgaagg aactgagcct 150

 gatgaagagt caggaaatgg agcacctgtt cctgtacctc caaagagaac 200

 agttaaaaga aatataccca agctggatgc tcagagatta atttcagaga 250

 gaggacttcc agccttaagg catgtatttg ataaggcaaa attcaaaggt 300

 aaaggtcatg aggctgaaga cttgaagatg ctaatcagac acatggagca 350

 ctgggcacat aggctattcc ctaaactgca gtttgaggat tttattgaca 400

 gagttgaata cctgggaagt aaaaaggaag ttcagacctg tttaaaacga 450

 attcgacttg atctccctat tttacatgaa gattttgtta gcaataatga 500

 tgaagttgcg gagaataatg aacatgatgt cacttctact gaattagatc 550

 cctttctgac aaacttatct gaaagtgaga tgtttgcttc tgagttaagt 600

 agaagcctaa cagaagagca acaacgaaga attgagagaa ataaacaact 650

 ggccttggaa agaaggcagg caaagctgct gagtaatagt cagaccctag 700

 gaaatgatat gttaatgaat acacccaggg cacacacggt tgaagaggtt 750

 aatactgatg aggatcaaaa ggaggagtca aatggattaa acgaagacat 800

 tctggacaat ccatgtaatg atgctattgc caatacttta aatgaagagg 850

 aaacactgct ggaccagtct tttaaaaatg tgcaacagca acttgatgct 900

 acatccagaa atattactga agctagataa gtttccatta agagaaaatg 950

 tatctgttaa gtcatcgtcc tgcaagcttg gcgttactat gtattttttc 1000

 ttcttggagt gaaaatcctt agatagtaaa actgttatag attattgttt 1050

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 1077

<210> 3388
<211> 301
<212> PRT
<213> Homo sapien

<400> 3388
 Met Leu Glu Pro Gln Glu Asn Gly Val Ile Asp Leu Pro Asp Tyr
   1               5                  10                  15

 Glu His Val Glu Asp Glu Thr Phe Pro Pro Phe Pro Pro Pro Ala
                  20                  25                  30

 Ser Pro Glu Arg Gln Asp Gly Glu Gly Thr Glu Pro Asp Glu Glu
                  35                  40                  45

 Ser Gly Asn Gly Ala Pro Val Pro Val Pro Pro Lys Arg Thr Val
                  50                  55                  60

 Lys Arg Asn Ile Pro Lys Leu Asp Ala Gln Arg Leu Ile Ser Glu
                  65                  70                  75

 Arg Gly Leu Pro Ala Leu Arg His Val Phe Asp Lys Ala Lys Phe
                  80                  85                  90

 Lys Gly Lys Gly His Glu Ala Glu Asp Leu Lys Met Leu Ile Arg
                  95                 100                 105

 His Met Glu His Trp Ala His Arg Leu Phe Pro Lys Leu Gln Phe
                 110                 115                 120

 Glu Asp Phe Ile Asp Arg Val Glu Tyr Leu Gly Ser Lys Lys Glu
                 125                 130                 135

 Val Gln Thr Cys Leu Lys Arg Ile Arg Leu Asp Leu Pro Ile Leu
                 140                 145                 150

 His Glu Asp Phe Val Ser Asn Asn Asp Glu Val Ala Glu Asn Asn
                 155                 160                 165

 Glu His Asp Val Thr Ser Thr Glu Leu Asp Pro Phe Leu Thr Asn
                 170                 175                 180

 Leu Ser Glu Ser Glu Met Phe Ala Ser Glu Leu Ser Arg Ser Leu
                 185                 190                 195

 Thr Glu Glu Gln Gln Arg Arg Ile Glu Arg Asn Lys Gln Leu Ala
                 200                 205                 210

 Leu Glu Arg Arg Gln Ala Lys Leu Leu Ser Asn Ser Gln Thr Leu
                 215                 220                 225

 Gly Asn Asp Met Leu Met Asn Thr Pro Arg Ala His Thr Val Glu
                 230                 235                 240

 Glu Val Asn Thr Asp Glu Asp Gln Lys Glu Glu Ser Asn Gly Leu
                 245                 250                 255

 Asn Glu Asp Ile Leu Asp Asn Pro Cys Asn Asp Ala Ile Ala Asn
                 260                 265                 270

 Thr Leu Asn Glu Glu Glu Thr Leu Leu Asp Gln Ser Phe Lys Asn
                 275                 280                 285

 Val Gln Gln Gln Leu Asp Ala Thr Ser Arg Asn Ile Thr Glu Ala
                 290                 295                 300

 Arg


<210> 3389
<211> 3257
<212> DNA
<213> Homo sapien

<400> 3389
 ggcatgatgg gcacctggag ggccgcactc ccgttccagc caggctgagc 50

 cttctgtccc ctgcctctgg ggcctgggaa ccccccttct tctttctcct 100

 gaatggcacc cccgccctag aatccagaca ccgagtttcc cactgtggct 150

 ggttcaaggg tatgtgagag ctccctggtg acagtctgtg gctgagcatg 200

 gccctcccag ccctgggcct ggacccctgg agcctcctgg gccttttcct 250

 cttccaactg cttcagctgc tgctgccgac gacgaccgcg gggggaggcg 300

 ggcaggggcc catgcccagg gtcagatact atgcagggga tgaacgtagg 350

 gcacttagct tcttccacca gaagggcctc caggattttg acactctgct 400

 cctgagtggt gatggaaata ctctctacgt gggggctcga gaagccattc 450

 tggccttgga tatccaggat ccaggggtcc ccaggctaaa gaacatgata 500

 ccgtggccag ccagtgacag aaaaaagagt gaatgtgcct ttaagaagaa 550

 gagcaatgag acacagtgtt tcaacttcat ccgtgtcctg gtttcttaca 600

 atgtcaccca tctctacacc tgcggcacct tcgccttcag ccctgcttgt 650

 accttcattg aacttcaaga ttcctacctg ttgcccatct cggaggacaa 700

 ggtcatggag ggaaaaggcc aaagcccctt tgaccccgct cacaagcata 750

 cggctgtctt ggtggatggg atgctctatt ctggtactat gaacaacttc 800

 ctgggcagtg agcccatcct gatgcgcaca ctgggatccc agcctgtcct 850

 caagaccgac aacttcctcc gctggctgca tcatgacgcc tcctttgtgg 900

 cagccatccc ttcgacccag gtcgtctact tcttcttcga ggagacagcc 950

 agcgagtttg acttctttga gaggctccac acatcgcggg tggctagagt 1000

 ctgcaagaat gacgtgggcg gcgaaaagct gctgcagaag aagtggacca 1050

 ccttcctgaa ggcccagctg ctctgcaccc agccggggca gctgcccttc 1100

 aacgtcatcc gccacgcggt cctgctcccc gccgattctc ccacagctcc 1150

 ccacatctac gcagtcttca cctcccagtg gcaggttggc gggaccagga 1200

 gctctgcggt ttgtgccttc tctctcttgg acattgaacg tgtctttaag 1250

 gggaaataca aagagttgaa caaagaaact tcacgctgga ctacttatag 1300

 gggccctgag accaaccccc ggccaggcag ttgctcagtg ggcccctcct 1350

 ctgataaggc cctgaccttc atgaaggacc atttcctgat ggatgagcaa 1400

 gtggtgggga cgcccctgct ggtgaaatct ggcgtggagt atacacggct 1450

 tgcagtggag acagcccagg gccttgatgg gcacagccat cttgtcatgt 1500

 acctgggaac caccacaggg tcgctccaca aggctgtggt aagtggggac 1550

 agcagtgctc atctggtgga agagattcag ctgttccctg accctgaacc 1600

 tgttcgcaac ctgcagctgg cccccaccca gggtgcagtg tttgtaggct 1650

 tctcaggagg tgtctggagg gtgccccgag ccaactgtag tgtctatgag 1700

 agctgtgtgg actgtgtcct tgcccgggac ccccactgtg cctgggaccc 1750

 tgagtcccga acctgttgcc tcctgtctgc ccccaacctg aactcctgga 1800

 agcaggacat ggagcggggg aacccagagt gggcatgtgc cagtggcccc 1850

 atgagcagga gccttcggcc tcagagccgc ccgcaaatca ttaaagaagt 1900

 cctggctgtc cctaactcca tcctggagct cccctgcccc cacctgtcag 1950

 ccttggcctc ttattattgg agtcatggcc cagcagcagt cccagaagcc 2000

 tcttccactg tctacaatgg ctccctcttg ctgatagtgc aggatggagt 2050

 tgggggtctc taccagtgct gggcaactga gaatggcttt tcataccctg 2100

 tgatctccta ctgggtggac agccaggacc agaccctggc cctggatcct 2150

 gaactggcag gcatcccccg ggagcatgtg aaggtcccgt tgaccagggt 2200

 cagtggtggg gccgccctgg ctgcccagca gtcctactgg ccccactttg 2250

 tcactgtcac tgtcctcttt gccttagtgc tttcaggagc cctcatcatc 2300

 ctcgtggcct ccccattgag agcactccgg gctcggggca aggttcaggg 2350

 ctgtgagacc ctgcgccctg gggagaaggc cccgttaagc agagagcaac 2400

 acctccagtc tcccaaggaa tgcaggacct ctgccagtga tgtggacgct 2450

 gacaacaact gcctaggcac tgaggtagct taaactctag gcacaggccg 2500

 gggctgcggt gcaggcacct ggccatgctg gctgggcggc ccaagcacag 2550

 ccctgactag gatgacagca gcacaaaaga ccacctttct cccctgagag 2600

 gagcttctgc tactctgcat cactgatgac actcagcagg gtgatgcaca 2650

 gcagtctgcc tcccctatgg gactcccttc taccaagcac atgagctctc 2700

 taacagggtg ggggctaccc ccagacctgc tcctacactg atattgaaga 2750

 acctggagag gatccttcag ttctggccat tccagggacc ctccagaaac 2800

 acagtgtttc aagagaccct aaaaaacctg cctgtcccag gaccctatgg 2850

 taatgaacac caaacatcta aacaatcata tgctaacatg ccactcctgg 2900

 aaactccact ctgaagctgc cgctttggac accaacactc ccttctccca 2950

 gggtcatgca gggatctgct ccctcctgct tcccttacca gtcgtgcacc 3000

 gctgactccc aggaagtctt tcctgaagtc tgaccacctt tcttcttgct 3050

 tcagttgggg cagactctga tcccttctgc cctggcagaa tggcaggggt 3100

 aatctgagcc ttcttcactc ctttacccta gctgacccct tcacctctcc 3150

 ccctcccttt tcctttgttt tgggattcag aaaactgctt gtcagagact 3200

 gtttattttt tattaaaaat ataaggctta aaaaaaaaaa aaaaaaaaaa 3250

 aaaaaaa 3257

<210> 3390
<211> 761
<212> PRT
<213> Homo sapien

<400> 3390
 Met Ala Leu Pro Ala Leu Gly Leu Asp Pro Trp Ser Leu Leu Gly
   1               5                  10                  15

 Leu Phe Leu Phe Gln Leu Leu Gln Leu Leu Leu Pro Thr Thr Thr
                  20                  25                  30

 Ala Gly Gly Gly Gly Gln Gly Pro Met Pro Arg Val Arg Tyr Tyr
                  35                  40                  45

 Ala Gly Asp Glu Arg Arg Ala Leu Ser Phe Phe His Gln Lys Gly
                  50                  55                  60

 Leu Gln Asp Phe Asp Thr Leu Leu Leu Ser Gly Asp Gly Asn Thr
                  65                  70                  75

 Leu Tyr Val Gly Ala Arg Glu Ala Ile Leu Ala Leu Asp Ile Gln
                  80                  85                  90

 Asp Pro Gly Val Pro Arg Leu Lys Asn Met Ile Pro Trp Pro Ala
                  95                 100                 105

 Ser Asp Arg Lys Lys Ser Glu Cys Ala Phe Lys Lys Lys Ser Asn
                 110                 115                 120

 Glu Thr Gln Cys Phe Asn Phe Ile Arg Val Leu Val Ser Tyr Asn
                 125                 130                 135

 Val Thr His Leu Tyr Thr Cys Gly Thr Phe Ala Phe Ser Pro Ala
                 140                 145                 150

 Cys Thr Phe Ile Glu Leu Gln Asp Ser Tyr Leu Leu Pro Ile Ser
                 155                 160                 165

 Glu Asp Lys Val Met Glu Gly Lys Gly Gln Ser Pro Phe Asp Pro
                 170                 175                 180

 Ala His Lys His Thr Ala Val Leu Val Asp Gly Met Leu Tyr Ser
                 185                 190                 195

 Gly Thr Met Asn Asn Phe Leu Gly Ser Glu Pro Ile Leu Met Arg
                 200                 205                 210

 Thr Leu Gly Ser Gln Pro Val Leu Lys Thr Asp Asn Phe Leu Arg
                 215                 220                 225

 Trp Leu His His Asp Ala Ser Phe Val Ala Ala Ile Pro Ser Thr
                 230                 235                 240

 Gln Val Val Tyr Phe Phe Phe Glu Glu Thr Ala Ser Glu Phe Asp
                 245                 250                 255

 Phe Phe Glu Arg Leu His Thr Ser Arg Val Ala Arg Val Cys Lys
                 260                 265                 270

 Asn Asp Val Gly Gly Glu Lys Leu Leu Gln Lys Lys Trp Thr Thr
                 275                 280                 285

 Phe Leu Lys Ala Gln Leu Leu Cys Thr Gln Pro Gly Gln Leu Pro
                 290                 295                 300

 Phe Asn Val Ile Arg His Ala Val Leu Leu Pro Ala Asp Ser Pro
                 305                 310                 315

 Thr Ala Pro His Ile Tyr Ala Val Phe Thr Ser Gln Trp Gln Val
                 320                 325                 330

 Gly Gly Thr Arg Ser Ser Ala Val Cys Ala Phe Ser Leu Leu Asp
                 335                 340                 345

 Ile Glu Arg Val Phe Lys Gly Lys Tyr Lys Glu Leu Asn Lys Glu
                 350                 355                 360

 Thr Ser Arg Trp Thr Thr Tyr Arg Gly Pro Glu Thr Asn Pro Arg
                 365                 370                 375

 Pro Gly Ser Cys Ser Val Gly Pro Ser Ser Asp Lys Ala Leu Thr
                 380                 385                 390

 Phe Met Lys Asp His Phe Leu Met Asp Glu Gln Val Val Gly Thr
                 395                 400                 405

 Pro Leu Leu Val Lys Ser Gly Val Glu Tyr Thr Arg Leu Ala Val
                 410                 415                 420

 Glu Thr Ala Gln Gly Leu Asp Gly His Ser His Leu Val Met Tyr
                 425                 430                 435

 Leu Gly Thr Thr Thr Gly Ser Leu His Lys Ala Val Val Ser Gly
                 440                 445                 450

 Asp Ser Ser Ala His Leu Val Glu Glu Ile Gln Leu Phe Pro Asp
                 455                 460                 465

 Pro Glu Pro Val Arg Asn Leu Gln Leu Ala Pro Thr Gln Gly Ala
                 470                 475                 480

 Val Phe Val Gly Phe Ser Gly Gly Val Trp Arg Val Pro Arg Ala
                 485                 490                 495

 Asn Cys Ser Val Tyr Glu Ser Cys Val Asp Cys Val Leu Ala Arg
                 500                 505                 510

 Asp Pro His Cys Ala Trp Asp Pro Glu Ser Arg Thr Cys Cys Leu
                 515                 520                 525

 Leu Ser Ala Pro Asn Leu Asn Ser Trp Lys Gln Asp Met Glu Arg
                 530                 535                 540

 Gly Asn Pro Glu Trp Ala Cys Ala Ser Gly Pro Met Ser Arg Ser
                 545                 550                 555

 Leu Arg Pro Gln Ser Arg Pro Gln Ile Ile Lys Glu Val Leu Ala
                 560                 565                 570

 Val Pro Asn Ser Ile Leu Glu Leu Pro Cys Pro His Leu Ser Ala
                 575                 580                 585

 Leu Ala Ser Tyr Tyr Trp Ser His Gly Pro Ala Ala Val Pro Glu
                 590                 595                 600

 Ala Ser Ser Thr Val Tyr Asn Gly Ser Leu Leu Leu Ile Val Gln
                 605                 610                 615

 Asp Gly Val Gly Gly Leu Tyr Gln Cys Trp Ala Thr Glu Asn Gly
                 620                 625                 630

 Phe Ser Tyr Pro Val Ile Ser Tyr Trp Val Asp Ser Gln Asp Gln
                 635                 640                 645

 Thr Leu Ala Leu Asp Pro Glu Leu Ala Gly Ile Pro Arg Glu His
                 650                 655                 660

 Val Lys Val Pro Leu Thr Arg Val Ser Gly Gly Ala Ala Leu Ala
                 665                 670                 675

 Ala Gln Gln Ser Tyr Trp Pro His Phe Val Thr Val Thr Val Leu
                 680                 685                 690

 Phe Ala Leu Val Leu Ser Gly Ala Leu Ile Ile Leu Val Ala Ser
                 695                 700                 705

 Pro Leu Arg Ala Leu Arg Ala Arg Gly Lys Val Gln Gly Cys Glu
                 710                 715                 720

 Thr Leu Arg Pro Gly Glu Lys Ala Pro Leu Ser Arg Glu Gln His
                 725                 730                 735

 Leu Gln Ser Pro Lys Glu Cys Arg Thr Ser Ala Ser Asp Val Asp
                 740                 745                 750

 Ala Asp Asn Asn Cys Leu Gly Thr Glu Val Ala
                 755                 760

<210> 3391
<211> 2605
<212> DNA
<213> Homo sapien

<400> 3391
 atacctttga gtcttgcaga agagaaacta ccaacaggca ttaatcctct 50

 cactctacac atcatgagaa ggacaaaaga atatgtaagt aatgacgcgg 100

 cacagtcaga tgatgaagag aagttacagt ctcagccaac agatactgat 150

 ggtggaaggt taaaacagaa aacgactcaa ctaaagaagt ttcttggaaa 200

 atcagtaaag agagcaaagc accttgctga ggaatatggt gaacgtgcta 250

 taaataaagt taaaagtgtt agagatgaag tgtttcatac tgatcaagat 300

 gatccttcat caagtgatga tgaaggaatg ccatacacaa gaccagttaa 350

 attcaaagca gcacacggtt tcaaaggacc ttatgatttt gatcagatca 400

 aagtggtgca agatcttagt ggtgaacata tgggagctgt ttggaccatg 450

 aaattttctc actgtggccg attacttgcc tcagctggac aagacaatgt 500

 agtgagaata tgggctttaa aaaatgcttt tgactatttc aacaatatgc 550

 gaatgaaata caatactgaa ggacgtgtgt ccccatcacc ctctcaggaa 600

 agtctaagtt catcaaaatc ggatacagat acaggggtat gcagtggaac 650

 tgatgaagac cctgatgata aaaacgcacc ctttcggcaa cggccatttt 700

 gcaaatataa aggacatact gctgatctcc ttgatctttc atggtctaaa 750

 aactactttc ttctttcttc ttcaatggat aaaacagtca gattatggca 800

 catttctcga agagaatgcc tttgctgttt tcaacatata gatactgcca 850

 tagcttttca tccaagagat gacaggtatt ttctaagtgg gtctttggat 900

 ggaaagctcc gcctttggaa catacctgac aaaaaagtgg ctttgtggaa 950

 tgaagtagat ggtcagacaa aattgatcac agctgcaaat ttctgtcaga 1000

 atggcaaata tgcagtgatt gggacatatg atggcagatg tattttctat 1050

 gatacagagc atttgaaata ccatacacaa atacatgtcc gatctactag 1100

 agggcgcaac aaggttggaa gaaaaattac tggcattgag cctttacctg 1150

 gagaaaataa gatattggta acctcaaatg actccagaat cagactatat 1200

 gatttgagag atttgtcact atccatgaag tataagggtt acgtcaatag 1250

 cagcagccag atcaagcaag tttcagccat gattttactt acctcgttag 1300

 tggttcagaa gataagtatg tttatatctg gagtacctac catgacctaa 1350

 gcaagtttac ttcagtcagg agagatcgta atgacttctg ggaaggtatt 1400

 aaagcccaca atgcagttgt tacatcagcc atctttgcac caaacccaag 1450

 tttgatgtta tctttggatg tgcaatctga aaaatcagaa gggaacgaga 1500

 aaagtgaaga tgctgaagtt ttggatgcca caccttctgg tattatgaag 1550

 acagataaca cagaagttct tctctctgct gacttcactg gagcaatcaa 1600

 agtgtttgtt aataaaagaa aaaatgtatc ttaatttgaa atggcattta 1650

 aaataaacat atcagtaagt ttctatatgt atcaaaactg aaaaaatagt 1700

 gttccaggct aacatacttt tttaattttt attgaaagtt gttcaaatat 1750

 aatatattct ttgagaggca gtgttaatga tctaggaaac cctgggctga 1800

 tagagtagaa aggaatatgg ctagaataac attgccaaac attaggcttt 1850

 atgttttgtt atgtttgtgt tttcgttgta taattatgaa catgcacaag 1900

 tttctgcatg aaaagatatt aatatattaa tcacatgtat gtgccttttg 1950

 gttacatgca ttaaatctaa cagagttaaa ttatttcagt ggctcttttg 2000

 gcctcttact aggggggata gtcttgtttc tagcttaaac aatttttttt 2050

 ttgcacaaaa tttcattttt aataaaagtg gtatcttttg actgagttat 2100

 tgttttgaaa atggtatata ggtttccagt aggtcaacaa ccatatgtaa 2150

 atggttttta taaatttctc aatttgggga caagattttt ttgtggtcta 2200

 aattgtgggc ttaagattct tttctttata tgtgtacata taattttttt 2250

 ttctttgcca cactggagca caatgtttct atgtaaagaa ttattttcat 2300

 tctttatcca tgagcaccag gctttgctca cttaaaaaaa aattaagcca 2350

 cattaaggag tgagtcttct tttttacaat aatgtaaaaa ttaaactgtt 2400

 tacatttttt taaagcattg tagtttttaa aaattaagct gttttgtttt 2450

 gtgttgttga atttgaaagc ctttgtaaat atcaatataa tgtaccaatg 2500

 aaataacatc tggggcaatg aaaccctgat catgttgttg atggttagca 2550

 tatgtttctg aaaattaaat atgtattatt aaaagttggt ctccaacact 2600

 tgttt 2605

<210> 3392
<211> 428
<212> PRT
<213> Homo sapien

<400> 3392
 Met Arg Arg Thr Lys Glu Tyr Val Ser Asn Asp Ala Ala Gln Ser
   1               5                  10                  15

 Asp Asp Glu Glu Lys Leu Gln Ser Gln Pro Thr Asp Thr Asp Gly
                  20                  25                  30

 Gly Arg Leu Lys Gln Lys Thr Thr Gln Leu Lys Lys Phe Leu Gly
                  35                  40                  45

 Lys Ser Val Lys Arg Ala Lys His Leu Ala Glu Glu Tyr Gly Glu
                  50                  55                  60

 Arg Ala Ile Asn Lys Val Lys Ser Val Arg Asp Glu Val Phe His
                  65                  70                  75

 Thr Asp Gln Asp Asp Pro Ser Ser Ser Asp Asp Glu Gly Met Pro
                  80                  85                  90

 Tyr Thr Arg Pro Val Lys Phe Lys Ala Ala His Gly Phe Lys Gly
                  95                 100                 105

 Pro Tyr Asp Phe Asp Gln Ile Lys Val Val Gln Asp Leu Ser Gly
                 110                 115                 120

 Glu His Met Gly Ala Val Trp Thr Met Lys Phe Ser His Cys Gly
                 125                 130                 135

 Arg Leu Leu Ala Ser Ala Gly Gln Asp Asn Val Val Arg Ile Trp
                 140                 145                 150

 Ala Leu Lys Asn Ala Phe Asp Tyr Phe Asn Asn Met Arg Met Lys
                 155                 160                 165

 Tyr Asn Thr Glu Gly Arg Val Ser Pro Ser Pro Ser Gln Glu Ser
                 170                 175                 180

 Leu Ser Ser Ser Lys Ser Asp Thr Asp Thr Gly Val Cys Ser Gly
                 185                 190                 195

 Thr Asp Glu Asp Pro Asp Asp Lys Asn Ala Pro Phe Arg Gln Arg
                 200                 205                 210

 Pro Phe Cys Lys Tyr Lys Gly His Thr Ala Asp Leu Leu Asp Leu
                 215                 220                 225

 Ser Trp Ser Lys Asn Tyr Phe Leu Leu Ser Ser Ser Met Asp Lys
                 230                 235                 240

 Thr Val Arg Leu Trp His Ile Ser Arg Arg Glu Cys Leu Cys Cys
                 245                 250                 255

 Phe Gln His Ile Asp Thr Ala Ile Ala Phe His Pro Arg Asp Asp
                 260                 265                 270

 Arg Tyr Phe Leu Ser Gly Ser Leu Asp Gly Lys Leu Arg Leu Trp
                 275                 280                 285

 Asn Ile Pro Asp Lys Lys Val Ala Leu Trp Asn Glu Val Asp Gly
                 290                 295                 300

 Gln Thr Lys Leu Ile Thr Ala Ala Asn Phe Cys Gln Asn Gly Lys
                 305                 310                 315

 Tyr Ala Val Ile Gly Thr Tyr Asp Gly Arg Cys Ile Phe Tyr Asp
                 320                 325                 330

 Thr Glu His Leu Lys Tyr His Thr Gln Ile His Val Arg Ser Thr
                 335                 340                 345

 Arg Gly Arg Asn Lys Val Gly Arg Lys Ile Thr Gly Ile Glu Pro
                 350                 355                 360

 Leu Pro Gly Glu Asn Lys Ile Leu Val Thr Ser Asn Asp Ser Arg
                 365                 370                 375

 Ile Arg Leu Tyr Asp Leu Arg Asp Leu Ser Leu Ser Met Lys Tyr
                 380                 385                 390

 Lys Gly Tyr Val Asn Ser Ser Ser Gln Ile Lys Gln Val Ser Ala
                 395                 400                 405

 Met Ile Leu Leu Thr Ser Leu Val Val Gln Lys Ile Ser Met Phe
                 410                 415                 420

 Ile Ser Gly Val Pro Thr Met Thr
                 425

<210> 3393
<211> 1870
<212> DNA
<213> Homo sapien

<400> 3393
 aaaaaacaac catttcctct ctgctgagag ccagggaagg cgagctctgc 50

 gcacacgggc gtccctgcag cagccactct gctttccagg accggccaac 100

 tgccctggag gcatccacac aggggcccag gcagcacaga ggagctgtga 150

 acccgctcca caccggccac cctgcccgga gcctggcact cacagcaggc 200

 cggtgctaag gagtgtggcg cgggctcgac tcccactgct gccggcctcc 250

 cgagtgactc tgttttccac tgctgcaggc gagaagaggc acgcgcggca 300

 caggccggcc tccgcttccc gggaagacgg cgcactcctg gccctgggtt 350

 cttgctgctg cccaccctct gctccctggg atgggccccg aggcgagcag 400

 cttcagcaca ggcctggccc tgctccaggt gcaggaagga ggataaggcc 450

 gggccgagag gcggcacacc tggaccatcc catgggcctc cgcccgcgcc 500

 gccccgagga tgagtggtga tgtcctctag ccacccctag cagcgtcggc 550

 tctccctgga cgtgcggccg cggactggga cttggctttc tccggataag 600

 cggcggcacc ggcgtcagcg atgaccgtgc agagactcgt ggccgcggcc 650

 gtgctggtgg ccctggtctc actcatcctc aacaacgtgg cggccttcac 700

 ctccaactgg gtgtgccaga cgctggagga tgggcgcagg cgcagcgtgg 750

 ggctgtggag gtcctgctgg ctggtggaca ggacccgggg agggccgagc 800

 cctggggcca gagccggcca ggtggacgca catgactgtg aggcgctggg 850

 ctggggctcc gaggcagccg gcttccagga gtcccgaggc accgtcaaac 900

 tgcagttcga catgatgcgc gcctgcaacc tggtggccac ggccgcgctc 950

 accgcaggcc agctcacctt cctcctgggg ctggtgggcc tgcccctgct 1000

 gtcacccgac gccccgtgct gggaggaggc catggccgct gcattccaac 1050

 tggcgagttt tgtcctggtc atcgggctcg tgactttcta cagaattggc 1100

 catacaccaa cctgtcctgg tcctgctacc tgaacattgg cgcctgcctt 1150

 ctggccacgc tggcggcagc catgctcatc tggaacattc tccacaagag 1200

 ggaggactgc atggcccccc gggtgattgt catcagccgc tccctgacag 1250

 cgcgctttcg ccgtgggctg gacaatgact acgtggagtc accatgctga 1300

 gtcgcccttc tcagcgttcc atcgatgcac acctgctatc gtggaacagc 1350

 ctagaaacca agggactcca ccaccaagtc acttcccctg ctcgtgcaga 1400

 ggcacgggat gagtctgggt gacctctgcg ccatgcgtgc gagacacgtg 1450

 tgcgtttact gttatgtcgg tcatatgtct gtacgtgtcg tgggccaacc 1500

 tcgttctgcc tccagctttc ctggttagcg caacgcggct ccacgaccac 1550

 acgcacttca gggtggaagc tggaagctga gacacaggtt aggtggcgcg 1600

 aggctgccct gcgctccgct ttgctttggg attaatttat tctgcatctg 1650

 ctgagagggg caccccagcc atatcttaca ctttggtaaa gcagaaaacc 1700

 aggaaaattt tcttaaaata tccacaatat tccttgagtg agtcagaatc 1750

 tatagccggt tagtgatggt ttcaggcaga atcgtgttcg tgtctgtttt 1800

 gctcgattcc tttcctaagt taaataaatg caagcctctg aacttctgtc 1850

 tataaaaaaa aaaaaaaaaa 1870

<210> 3394
<211> 170
<212> PRT
<213> Homo sapien

<400> 3394
 Met Thr Val Gln Arg Leu Val Ala Ala Ala Val Leu Val Ala Leu
   1               5                  10                  15

 Val Ser Leu Ile Leu Asn Asn Val Ala Ala Phe Thr Ser Asn Trp
                  20                  25                  30

 Val Cys Gln Thr Leu Glu Asp Gly Arg Arg Arg Ser Val Gly Leu
                  35                  40                  45

 Trp Arg Ser Cys Trp Leu Val Asp Arg Thr Arg Gly Gly Pro Ser
                  50                  55                  60

 Pro Gly Ala Arg Ala Gly Gln Val Asp Ala His Asp Cys Glu Ala
                  65                  70                  75

 Leu Gly Trp Gly Ser Glu Ala Ala Gly Phe Gln Glu Ser Arg Gly
                  80                  85                  90

 Thr Val Lys Leu Gln Phe Asp Met Met Arg Ala Cys Asn Leu Val
                  95                 100                 105

 Ala Thr Ala Ala Leu Thr Ala Gly Gln Leu Thr Phe Leu Leu Gly
                 110                 115                 120

 Leu Val Gly Leu Pro Leu Leu Ser Pro Asp Ala Pro Cys Trp Glu
                 125                 130                 135

 Glu Ala Met Ala Ala Ala Phe Gln Leu Ala Ser Phe Val Leu Val
                 140                 145                 150

 Ile Gly Leu Val Thr Phe Tyr Arg Ile Gly His Thr Pro Thr Cys
                 155                 160                 165

 Pro Gly Pro Ala Thr
                 170

<210> 3395
<211> 1542
<212> DNA
<213> Homo sapien

<400> 3395
 gggcttctgg ctcggcgcag caggttccat tcacgccaag tctgttggca 50

 gtggcagttg tagggccaag ggcggttgta ggacccggag cagccggaca 100

 tggaacaacc gtggccgcct ccgggaccct ggagcctccc tcgggccggg 150

 ggtgaggctg aggaagagag tgacttcgac gtgttcccca gttctccccg 200

 ctgcccgcag ctgccaggcg gcggcgccca gatgtatagc catggaattg 250

 aattggcttg ccaaaagcag aaagagtttg tgaagagctc tgtggcgtgc 300

 aaatggaatc ttgctgaagc tcaacagaaa cttggtagct tagcactgca 350

 taattctgag tccttggatc aggagcatgc caaagcacaa acagcagtat 400

 cagaactgag gcaacgggaa gaagagtggc gacagaaaga agaagctcta 450

 gtacaaagag agaagatgtg tctgtggagc acggatgcca ttagcaagga 500

 tgtttttaat aagagtttta ttaatcaaga taaaagaaaa gacacagaag 550

 atgaagataa atcagaatca tttatgcaaa aatatgagca aaaaatcaga 600

 cattttggta tgttgagtcg atgggatgat agccagagat ttttgtctga 650

 ccatccatac cttgtatgtg aagaaactgc taaatatctt attttatggt 700

 gttttcacct ggaagctgag aagaaagggg ctttaatgga acaaatagca 750

 catcaagctg ttgtaatgca gtttattatg gaaatggcca aaaactgtaa 800

 tgtggatcca agagggtgtt ttcgtttatt tttccagaaa gccaaagcag 850

 aggaagaagg ttattttgaa gcattcaaaa atgaacttga agctttcaag 900

 tcaagagtaa gactttattc tcaatcacaa agttttcaac ctatgacagt 950

 tcagaatcat gttccccatt ctggtgttgg atctataggt ttattagaat 1000

 ccttaccaca gagtccagat tatcttcagt attctatcag tacagctctc 1050

 tgcagcttaa actcggtggt acataaagaa gatgatgaac ccaaaatgat 1100

 ggacactgta taatttggtt aagactgctg aggccaagtg ctattttgtt 1150

 acaagaaagg aagaacttgg ctattttctt gacactttta tgggtgctgc 1200

 actttatttt tgtttggttt ttgatgggag ggaaagagta ctgaaatgtt 1250

 ttgtaaattt tttttaatgt gctgctaggt tttttgtttt gttttgttct 1300

 gaagagaaga gtggtaccat atgttgcagg aagtcaaact ggactttttg 1350

 tggctactaa atttgccttt aatcttattg ttctcaattt tggaatcaag 1400

 tatgaaaatc tgcacaaatg caatgtttac aagaactggt tgattctggg 1450

 aggcatctgc tacagtctct ttttatatgg atatgtacat gtcctattct 1500

 acaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1542

<210> 3396
<211> 337
<212> PRT
<213> Homo sapien

<400> 3396
 Met Glu Gln Pro Trp Pro Pro Pro Gly Pro Trp Ser Leu Pro Arg
   1               5                  10                  15

 Ala Gly Gly Glu Ala Glu Glu Glu Ser Asp Phe Asp Val Phe Pro
                  20                  25                  30

 Ser Ser Pro Arg Cys Pro Gln Leu Pro Gly Gly Gly Ala Gln Met
                  35                  40                  45

 Tyr Ser His Gly Ile Glu Leu Ala Cys Gln Lys Gln Lys Glu Phe
                  50                  55                  60

 Val Lys Ser Ser Val Ala Cys Lys Trp Asn Leu Ala Glu Ala Gln
                  65                  70                  75

 Gln Lys Leu Gly Ser Leu Ala Leu His Asn Ser Glu Ser Leu Asp
                  80                  85                  90

 Gln Glu His Ala Lys Ala Gln Thr Ala Val Ser Glu Leu Arg Gln
                  95                 100                 105

 Arg Glu Glu Glu Trp Arg Gln Lys Glu Glu Ala Leu Val Gln Arg
                 110                 115                 120

 Glu Lys Met Cys Leu Trp Ser Thr Asp Ala Ile Ser Lys Asp Val
                 125                 130                 135

 Phe Asn Lys Ser Phe Ile Asn Gln Asp Lys Arg Lys Asp Thr Glu
                 140                 145                 150

 Asp Glu Asp Lys Ser Glu Ser Phe Met Gln Lys Tyr Glu Gln Lys
                 155                 160                 165

 Ile Arg His Phe Gly Met Leu Ser Arg Trp Asp Asp Ser Gln Arg
                 170                 175                 180

 Phe Leu Ser Asp His Pro Tyr Leu Val Cys Glu Glu Thr Ala Lys
                 185                 190                 195

 Tyr Leu Ile Leu Trp Cys Phe His Leu Glu Ala Glu Lys Lys Gly
                 200                 205                 210

 Ala Leu Met Glu Gln Ile Ala His Gln Ala Val Val Met Gln Phe
                 215                 220                 225

 Ile Met Glu Met Ala Lys Asn Cys Asn Val Asp Pro Arg Gly Cys
                 230                 235                 240

 Phe Arg Leu Phe Phe Gln Lys Ala Lys Ala Glu Glu Glu Gly Tyr
                 245                 250                 255

 Phe Glu Ala Phe Lys Asn Glu Leu Glu Ala Phe Lys Ser Arg Val
                 260                 265                 270

 Arg Leu Tyr Ser Gln Ser Gln Ser Phe Gln Pro Met Thr Val Gln
                 275                 280                 285

 Asn His Val Pro His Ser Gly Val Gly Ser Ile Gly Leu Leu Glu
                 290                 295                 300

 Ser Leu Pro Gln Ser Pro Asp Tyr Leu Gln Tyr Ser Ile Ser Thr
                 305                 310                 315

 Ala Leu Cys Ser Leu Asn Ser Val Val His Lys Glu Asp Asp Glu
                 320                 325                 330

 Pro Lys Met Met Asp Thr Val
                 335

<210> 3397
<211> 2010
<212> DNA
<213> Homo sapien

<400> 3397
 gtcgactacc agaaaatact ttcaacataa atgaactctc caacttatta 50

 aacttttata tagatagagg aagacagctc tttcgggata accacctgat 100

 acctgcagaa acccccagtc ctgttatttt cagtgatttt ccatttatct 150

 ttaattcgct atccaaaatt aaattattgc aagctgattc acatataaag 200

 atgcagatgt cagaaaagaa agcatacatg cttatgcatg aaacaattct 250

 gcaaaaaaag gatgaatttc ctccatcacc cagatttata cttagagtca 300

 gacgaagtcg cctggttaaa gatgctctgc gtcaattaag tcaagctgaa 350

 gctactgact tctgcaaagt attagtggtt gaatttatta atgaaatttg 400

 tcctgagtct ggaggggtta gttcagagtt cttccactgt atgtttgaag 450

 agatgaccaa gccagaatat ggaatgttca tgtatcctga aatgtgttcc 500

 tgcatgtggt ttcctgccaa gcctaaacct gagaagaaaa gatatttcct 550

 ctttggaatg ctgtgtggac tctccttatt caatttaaat gttgctaacc 600

 ttcctttccc actggctctg tataaaaaac ttctggacca aaagccatca 650

 ttggaagatt taaaagaact cagtcctcgg ttggggaaga gtttgcaaga 700

 agttctagat gatgctgctg atgacattgg agatgcgctc tgcatacgct 750

 tttctataca ctgggaccaa aatgatgttg acttaattcc aaatgggatc 800

 tccatacctg tggaccaaac caacaagaga gactatgttt ctaagtatat 850

 tgattacatt ttcaacgtct ctgtaaaagc agtttatgag gaatttcaga 900

 gaggatttta tagagtctgt gagaaggaga tacttagaca tttctaccct 950

 gaagaactaa tgacagcaat cattggaaat actgattatg actggaaaca 1000

 gtttgaacag aattcaaagt atgagcaagg ataccaaaaa tcacatccta 1050

 ctatacagtt gttttggaag gctttccaca agctaacctt ggatgaaaag 1100

 aaaaaattcc tctttttcct tacaggacgt gataggctgc atgcaagagg 1150

 catacagaaa atggaaatag tatttcgctg tcctgaaact ttcagtgaaa 1200

 gagatcaccc aacatcaata acttgtcata atattctctc cctccctaag 1250

 tattctacaa tggaaagaat ggaggaagca ctccaagtag ccatcaacaa 1300

 caacagagga tttgtctcac ccatgctcac acagtcataa tcacctctga 1350

 gagactcagg gtgggctttc tcacacttgg atccttctgt tcttccttac 1400

 acctaaataa tacaagagat taatgaatag tggttagaag tagttgaggg 1450

 agagattggg ggaatgggga gatgatgatg atggtcaaag ggtgcaaaat 1500

 ctcacacaag actgaggcag gagaataggg tacagagata gggatctaag 1550

 gatgacttgg acacactccc tggcactgaa gagtctgaac actggcctgt 1600

 gattggtcca ttccaggacc ttcatttgca taaggtatca aaccacatca 1650

 gcctctgatt ggccatgggc cagacctgca ctctggccaa tgattggttc 1700

 attccaggac attcatttgc ataaggagtc aaaccacacc agtcttggat 1750

 tggctgtgag ccaattcacc tcagtctcta attggctgtg agtcagtctt 1800

 tcatttacat agggtgtaac catcaagaaa cctctacagg gtacttaagc 1850

 cccagaagat tttgctacca gggctcttga gccacttgct ctagcccact 1900

 cccaccctgt ggaatgtact ttcacttttg ctgcttcact gccttgtgct 1950

 ccaataaatc cactccttca ccacccaaaa aaaaaaaaaa aaaaaaaaaa 2000

 aaaaaaaaaa 2010

<210> 3398
<211> 379
<212> PRT
<213> Homo sapien

<400> 3398
 Met Gln Met Ser Glu Lys Lys Ala Tyr Met Leu Met His Glu Thr
   1               5                  10                  15

 Ile Leu Gln Lys Lys Asp Glu Phe Pro Pro Ser Pro Arg Phe Ile
                  20                  25                  30

 Leu Arg Val Arg Arg Ser Arg Leu Val Lys Asp Ala Leu Arg Gln
                  35                  40                  45

 Leu Ser Gln Ala Glu Ala Thr Asp Phe Cys Lys Val Leu Val Val
                  50                  55                  60

 Glu Phe Ile Asn Glu Ile Cys Pro Glu Ser Gly Gly Val Ser Ser
                  65                  70                  75

 Glu Phe Phe His Cys Met Phe Glu Glu Met Thr Lys Pro Glu Tyr
                  80                  85                  90

 Gly Met Phe Met Tyr Pro Glu Met Cys Ser Cys Met Trp Phe Pro
                  95                 100                 105

 Ala Lys Pro Lys Pro Glu Lys Lys Arg Tyr Phe Leu Phe Gly Met
                 110                 115                 120

 Leu Cys Gly Leu Ser Leu Phe Asn Leu Asn Val Ala Asn Leu Pro
                 125                 130                 135

 Phe Pro Leu Ala Leu Tyr Lys Lys Leu Leu Asp Gln Lys Pro Ser
                 140                 145                 150

 Leu Glu Asp Leu Lys Glu Leu Ser Pro Arg Leu Gly Lys Ser Leu
                 155                 160                 165

 Gln Glu Val Leu Asp Asp Ala Ala Asp Asp Ile Gly Asp Ala Leu
                 170                 175                 180

 Cys Ile Arg Phe Ser Ile His Trp Asp Gln Asn Asp Val Asp Leu
                 185                 190                 195

 Ile Pro Asn Gly Ile Ser Ile Pro Val Asp Gln Thr Asn Lys Arg
                 200                 205                 210

 Asp Tyr Val Ser Lys Tyr Ile Asp Tyr Ile Phe Asn Val Ser Val
                 215                 220                 225

 Lys Ala Val Tyr Glu Glu Phe Gln Arg Gly Phe Tyr Arg Val Cys
                 230                 235                 240

 Glu Lys Glu Ile Leu Arg His Phe Tyr Pro Glu Glu Leu Met Thr
                 245                 250                 255

 Ala Ile Ile Gly Asn Thr Asp Tyr Asp Trp Lys Gln Phe Glu Gln
                 260                 265                 270

 Asn Ser Lys Tyr Glu Gln Gly Tyr Gln Lys Ser His Pro Thr Ile
                 275                 280                 285

 Gln Leu Phe Trp Lys Ala Phe His Lys Leu Thr Leu Asp Glu Lys
                 290                 295                 300

 Lys Lys Phe Leu Phe Phe Leu Thr Gly Arg Asp Arg Leu His Ala
                 305                 310                 315

 Arg Gly Ile Gln Lys Met Glu Ile Val Phe Arg Cys Pro Glu Thr
                 320                 325                 330

 Phe Ser Glu Arg Asp His Pro Thr Ser Ile Thr Cys His Asn Ile
                 335                 340                 345

 Leu Ser Leu Pro Lys Tyr Ser Thr Met Glu Arg Met Glu Glu Ala
                 350                 355                 360

 Leu Gln Val Ala Ile Asn Asn Asn Arg Gly Phe Val Ser Pro Met
                 365                 370                 375

 Leu Thr Gln Ser


<210> 3399
<211> 1197
<212> DNA
<213> Homo sapien

<400> 3399
 tttcttcgcg gctgctcaag atgaaccgac tcttcgggaa agcgaaaccc 50

 aaggctccgc cgcccagcct gactgactgc attggcacgg tggacagtag 100

 agcagaatcc attgacaaga agatttctcg attggatgct gagctagtga 150

 agtataagga tcagatcaag aagatgagag agggtcctgc aaagaatatg 200

 gtcaagcaga aagccttgcg agttttaaag caaaagagga tgtatgagca 250

 gcagcgggac aatcttgccc aacagtcatt caacatggaa caagccaatt 300

 ataccatcca gtctttgaag gacaccaaga ccacggttga tgctatgaaa 350

 ctgggagtaa aggaaatgaa gaaggcatac aagcaagtga agatcgacca 400

 gattgaggat ttacaagacc agctagagga tatgatggaa gatgcaaatg 450

 aaatccaaga agcactgagt cgcagttatg gcaccccaga actggatgaa 500

 gatgatttag aagcagagtt ggatgcacta ggtgatgagc ttctggctga 550

 tgaagacagt tcttatttgg atgaggcagc atctgcacct gcaattccag 600

 aaggtgttcc cactgataca aaaaacaagg atggagttct ggtggatgaa 650

 tttggattgc cacagatccc tgcttcatag atttgcatca ttcaagcata 700

 tcttgtaaaa caaacacata ttatgggact aggaaatatt tatctttcca 750

 aatttgccat aacagattta ggtttctttc ctttctttga aggaaagttt 800

 aattacattg ctcttttatt ttttccatta agagactcat tgcttgggaa 850

 atgctttctt cgtactaaaa tttgattcct ttttttctta tgaaaaacga 900

 actcagttta aaagtatttt tagctcgtat gacttgtttt cattcattaa 950

 taataatttg aaataaaact aaggaaatgg aatcttaaaa gtctatgaca 1000

 gtgtaactct acagtcctca aaatgaccct gtaaatttgg ataagaccaa 1050

 agatgagatt attggggctg gtcatattat gattcagaat ccatttctat 1100

 tgtgggtatt atagggttgg gttaaaggtg atggcccttt ttgatgggtt 1150

 ttgttgtgtc ttgtgaacaa gtcgttactg tgtccattat tggaatg 1197

<210> 3400
<211> 219
<212> PRT
<213> Homo sapien

<400> 3400
 Met Asn Arg Leu Phe Gly Lys Ala Lys Pro Lys Ala Pro Pro Pro
   1               5                  10                  15

 Ser Leu Thr Asp Cys Ile Gly Thr Val Asp Ser Arg Ala Glu Ser
                  20                  25                  30

 Ile Asp Lys Lys Ile Ser Arg Leu Asp Ala Glu Leu Val Lys Tyr
                  35                  40                  45

 Lys Asp Gln Ile Lys Lys Met Arg Glu Gly Pro Ala Lys Asn Met
                  50                  55                  60

 Val Lys Gln Lys Ala Leu Arg Val Leu Lys Gln Lys Arg Met Tyr
                  65                  70                  75

 Glu Gln Gln Arg Asp Asn Leu Ala Gln Gln Ser Phe Asn Met Glu
                  80                  85                  90

 Gln Ala Asn Tyr Thr Ile Gln Ser Leu Lys Asp Thr Lys Thr Thr
                  95                 100                 105

 Val Asp Ala Met Lys Leu Gly Val Lys Glu Met Lys Lys Ala Tyr
                 110                 115                 120

 Lys Gln Val Lys Ile Asp Gln Ile Glu Asp Leu Gln Asp Gln Leu
                 125                 130                 135

 Glu Asp Met Met Glu Asp Ala Asn Glu Ile Gln Glu Ala Leu Ser
                 140                 145                 150

 Arg Ser Tyr Gly Thr Pro Glu Leu Asp Glu Asp Asp Leu Glu Ala
                 155                 160                 165

 Glu Leu Asp Ala Leu Gly Asp Glu Leu Leu Ala Asp Glu Asp Ser
                 170                 175                 180

 Ser Tyr Leu Asp Glu Ala Ala Ser Ala Pro Ala Ile Pro Glu Gly
                 185                 190                 195

 Val Pro Thr Asp Thr Lys Asn Lys Asp Gly Val Leu Val Asp Glu
                 200                 205                 210

 Phe Gly Leu Pro Gln Ile Pro Ala Ser
                 215

<210> 3401
<211> 3874
<212> DNA
<213> Homo sapien

<400> 3401
 gtattctccg ccgcccccac gccctcgagg tccccgccac cgaaccagcg 50

 gcggagcccg cccgcgcctc ccgcggcatt cccgcaccgg atcgctcctc 100

 gctggggcgg gacctggcct ggcggctctg gtcactatga gtgaaacatc 150

 tttcaaccta atatcagaaa aatgtgacat tctatccatt cttcgggacc 200

 atcctgaaaa caggatttac cggaggaaaa tcgaggaact cagcaaaagg 250

 ttcaccgcca tccgcaagac caaaggggat gggaactgct tctacagggc 300

 cttgggctat tcctacctgg agtccctgct ggggaagagc agggagatct 350

 tcaagttcaa agaacgcgta ctgcagaccc caaatgacct tctggctgct 400

 ggctttgagg agcacaagtt cagaaacttc ttcaatgctt tttacagtgt 450

 ggtggaactg gtagagaagg acggctcagt gtccagcctg ctgaaggtgt 500

 tcaacgacca gagtgcctcg gaccacatcg tgcagttcct gcgcctgctc 550

 acgtcggcct tcatcaggaa ccgagcagac ttcttccggc acttcattga 600

 tgaggagatg gacatcaaag acttctgcac tcacgaagta gagcccatgg 650

 ccacggagtg tgaccacatc cagatcacgg cgttgtcgca ggccctgagc 700

 attgccctgc aagtggagta cgtggacgag atggataccg ccctgaacca 750

 ccacgtgttc cctgaggccg ccaccccttc cgtttacctg ctctataaaa 800

 catcccacta caacatcctt tatgcagccg ataaacattg attaatttta 850

 ggccatgcag tggaacctgt cacctaatgg gactgcattc tgaatggaac 900

 attccggctc ttcaattttt taagcaattt agactgtagc aagaaaatgt 950

 gcagcctttt gggcaaagcc cctgggaacg aggcctaccc actatggact 1000

 atggtaactt ggtaggattt ttagtattta ttttaatgga gggacaaatg 1050

 ctttctaact gggcccccga ctccgcaccc cagttcgcag tgaggccctg 1100

 ggtgggtcac ctgccctctc tggacttgtt tcttcaactg gaggaggtcc 1150

 ctgcctatgc tgacattcca ttgtagaaaa atggggcctc tggtgtctct 1200

 ttaccagggg cagtgcctct ctgcggggga ggaaaagctc aaggttagct 1250

 gtcttaaccc aagtgactta ccaggcctac aaaagagtcc agtccagtca 1300

 cttgttggac tgggctctga cagatggcct attgaggtca acttgaatgt 1350

 gagggctgcg gtgtggtttc aaacattcat gatggatgta ttttcctacc 1400

 cctaacttaa ggagaaaaaa aaaaagactt cctttttttg ccaaagtcca 1450

 gaaaggggcc tttagccttt agtaggagct caaattgttg gggcccctct 1500

 acctctctca gggctagaac tgcctgactc ttggtggacg agcccttcag 1550

 ggttctgctt tcagccccac ctggacagag gcttacaaga ctagggtctg 1600

 gaccagaatc tgtgtatttc tgtctgggac caggaagctg cagctgtccc 1650

 atcatcccca gcaaatccta gaagtggagt ctggatactt caaggataga 1700

 agtgttggca cgcacagcca tggacccagc tgagcagagc agacgctttg 1750

 caggctgccc ctggcttctt cctccctttc ccgcttctgc tctctttatg 1800

 gactggtcag agggtaggtg ggaaagaaca gacaagccat ggaagttggc 1850

 agtggggaga tttccactgt ggaaaccgcc tgggaattcc ggccagcagc 1900

 ttcctccttc agccacctgg ccatacccct taaataagcc cctcaccttg 1950

 ctgcctcagg accttcaaga ttccatctgt gggctggccg gcaagatggc 2000

 accagtgggg acccacaccc tggctgggca gaggtgctgc tagcaacccc 2050

 tcttcctcta taagaggaaa tggaaaatgc agggtgtgga attgcccttt 2100

 ggggtccttc cttaattgaa ggccaccttc tcacaggttt cattctgcag 2150

 ggatttactg gaatctattg gtgctgctgc atgagtctgc tgacaacctg 2200

 actgcacaag gactgggtag cagactcctc agagtcctct tgacacaaat 2250

 gtcagatttg tgtcactctt ctgccttcgt gaaaagccaa tagcactctc 2300

 agatatcagg ggattttagt tccaagcagg gaccctggtt tccatactgc 2350

 cctcagctgg agtttggatc caaaggctct ggctaagtca ttatgtcact 2400

 ttctcacagg aatgtaaatt tgactgtcac ctctgaattt gttcagtgtc 2450

 ccaccatggt ctatgagaag tacactggaa gcgtgggggg aacacatgac 2500

 atgatttgtg aatatcatca tctttgccag acaagtctcc aggggatccc 2550

 tgtttcccaa ctgaaaggtg tgaacggaca cacacacagc ctggatgacg 2600

 ccttggctgt tctaaggggc tgtaaggtgg gctctgggcc ttccagctag 2650

 gctctcaagc acagcagaag cctcactggg ctgctatgtc tctgtatttg 2700

 tggcttgtgt ggtagcctca gaagcagagc tgtttggcag actggctgga 2750

 gaaattccct ctaggagact tgcctgtgct gtgcttccag gtcacagagc 2800

 cccccggaaa ctcacagggg ccctcttccc agaaaagaat ctattctatc 2850

 acttcagaat caggacactc aagctctggc agaggaaggc caagttactt 2900

 tcatggtctt accctctgct tttccccttt ttgcaaaaaa ccactggcca 2950

 aatccgaacc attgcccttg tttcccccac gttctctctc agatctttgt 3000

 ctcgaaggga aaacatagtg gatgaaaagg tgtggcaggc tttggcacct 3050

 tgttaaaatt tctagtcatc tgtggatgtt accttgcttg tccacagcag 3100

 ccagtcaccc tggccagtcc cacttcctgg ataattctct accctcaccc 3150

 cacagagcca tctctctcca gaccaaaagc tggaaggaga gttgctttga 3200

 gagcttgttt ttacaactgc atgtttatta tgatactttc tctccaaagg 3250

 aaacttttaa atcaatggga acaattagca acagaaagag cacagtccct 3300

 gcttttgact gggttcctat tttaagcaca aatgagagct ctggagccag 3350

 aatgccaggg ttctaacttc agcattcact tactagctgt atgatcttgg 3400

 ccaagtcact tcacctccct gagccccaat tcccaagttt gtgaaatggc 3450

 aacaatacct atgtgtcact ggattattgg ttaaaacaga atgagattcc 3500

 ttgtgtgaaa atagctatta tacctgacac actcatcgta tgggctctgc 3550

 aaagggatat tccccaacct gtccttcccg acaggaagca tagggcactg 3600

 cagatgggga agcatgtcac cttggcagtg actcggtggc ttcccaagca 3650

 ggagtgtcag gggaaccatg agagagagtc taggagccaa acacatcacc 3700

 accctgagca gatacaggag tggggagggg gctgtaactc agtgagtggc 3750

 ttccaggggc cccaggccct gctggatgtg ggccaagccc tacagcttcc 3800

 ctaggcagta agtaaaaaca ttctcctagc attaaaatgg tttccataaa 3850

 aaaaaaaaaa aaaaaaaaaa aaaa 3874

<210> 3402
<211> 234
<212> PRT
<213> Homo sapien

<400> 3402
 Met Ser Glu Thr Ser Phe Asn Leu Ile Ser Glu Lys Cys Asp Ile
   1               5                  10                  15

 Leu Ser Ile Leu Arg Asp His Pro Glu Asn Arg Ile Tyr Arg Arg
                  20                  25                  30

 Lys Ile Glu Glu Leu Ser Lys Arg Phe Thr Ala Ile Arg Lys Thr
                  35                  40                  45

 Lys Gly Asp Gly Asn Cys Phe Tyr Arg Ala Leu Gly Tyr Ser Tyr
                  50                  55                  60

 Leu Glu Ser Leu Leu Gly Lys Ser Arg Glu Ile Phe Lys Phe Lys
                  65                  70                  75

 Glu Arg Val Leu Gln Thr Pro Asn Asp Leu Leu Ala Ala Gly Phe
                  80                  85                  90

 Glu Glu His Lys Phe Arg Asn Phe Phe Asn Ala Phe Tyr Ser Val
                  95                 100                 105

 Val Glu Leu Val Glu Lys Asp Gly Ser Val Ser Ser Leu Leu Lys
                 110                 115                 120

 Val Phe Asn Asp Gln Ser Ala Ser Asp His Ile Val Gln Phe Leu
                 125                 130                 135

 Arg Leu Leu Thr Ser Ala Phe Ile Arg Asn Arg Ala Asp Phe Phe
                 140                 145                 150

 Arg His Phe Ile Asp Glu Glu Met Asp Ile Lys Asp Phe Cys Thr
                 155                 160                 165

 His Glu Val Glu Pro Met Ala Thr Glu Cys Asp His Ile Gln Ile
                 170                 175                 180

 Thr Ala Leu Ser Gln Ala Leu Ser Ile Ala Leu Gln Val Glu Tyr
                 185                 190                 195

 Val Asp Glu Met Asp Thr Ala Leu Asn His His Val Phe Pro Glu
                 200                 205                 210

 Ala Ala Thr Pro Ser Val Tyr Leu Leu Tyr Lys Thr Ser His Tyr
                 215                 220                 225

 Asn Ile Leu Tyr Ala Ala Asp Lys His
                 230

<210> 3403
<211> 3197
<212> DNA
<213> Homo sapien

<400> 3403
 ggaccacagc tcctcccgtg catccactcg gcctgggagg ttctggattt 50

 tggctgtcga gggagtttgc ctgcctctcc agagaaagat ggtcatgagg 100

 cccctgtgga gtctgcttct ctgggaagcc ctacttccca ttacagttac 150

 tggtgcccaa gtgctgagca aagtcggggg ctcggtgctg ctggtggcag 200

 cgcgtccccc tggcttccaa gtccgtgagg ctatctggcg atctctctgg 250

 ccttcagaag agctcctggc cacgtttttc cgaggctccc tggagactct 300

 gtaccattcc cgcttcctgg gccgagccca gctacacagc aacctcagcc 350

 tggagctcgg gccgctggag tctggagaca gcggcaactt ctccgtgttg 400

 atggtggaca caaggggcca gccctggacc cagaccctcc agctcaaggt 450

 gtacgatgca gtgcccaggc ccgtggtaca agtgttcatt gctgtagaaa 500

 gggatgctca gccctccaag acctgccagg ttttcttgtc ctgttgggcc 550

 cccaacatca gcgaaataac ctatagctgg cgacgggaga caaccatgga 600

 ctttggtatg gaaccacaca gcctcttcac agacggacag gtgctgagca 650

 tttccctggg accaggagac agagatgtgg cctattcctg cattgtctcc 700

 aaccctgtca gctgggactt ggccacagtc acgccctggg atagctgtca 750

 tcatgaggca gcaccaggga aggcctccta caaagatgtg ctgctggtgg 800

 tggtgcctgt ctcgctgctc ctgatgctgg ttactctctt ctctgcctgg 850

 cactggtgcc cctgctcagg gaaaaagaaa aaggatgtcc atgctgacag 900

 agtgggtcca gagacagaga acccccttgt gcaggatctg ccataaagga 950

 caatatgaac tgatgcctgg actatcagta accccactgc acaggcacac 1000

 gatgctctgg gacataactg gtgcctggaa atcaccatgg tcctcatatc 1050

 tcccatggga atcctgtcct gcctcgaagg agcagcctgg gcagccatca 1100

 caccacgagg acaggaagca ccagcacgtt tcacacctcc cccttccctc 1150

 tcccatcttc tcatatcctg gctcttctct gggcaagatg agccaagcag 1200

 aacattccat ccaggacact ggaagttctc caggatccag atccatgggg 1250

 acattaatag tccaaggcat tccctccccc accactattc ataaagtatt 1300

 aaccaactgg caccaaggaa ttgcctccag cctgagtcct aggctctaaa 1350

 agatattaca tatttgaact aatagaggaa ctctgagtca cccatgccag 1400

 catcagcttc agccccagac cctgcagttt gagatctgat gcttcctgag 1450

 ggccaaggca ttgctgtaag aaaaggtcta gaaataggtg aaagtgagag 1500

 gtgggggaca ggggtttctc tttctggcct aaggactttc aggtaatcag 1550

 agttcatggg ccctcaaagg taaattgcag ttgtagacac cgaggatggt 1600

 tgacaaccca tggttgagat gggcaccgtt ttgcaggaaa caccatatta 1650

 atagacatcc tcaccatctc catccgctct cacgcctcct gcaggatctg 1700

 ggagtgaggg tggagagtct ttcctcacgc tccagcacag tggccaggaa 1750

 aagaaatact gaatttgccc cagccaacag gacgttcttg cacaacttca 1800

 agaaaagcag ctcagctcag gatgagtctt cctgcctgaa actgagagag 1850

 tgaagaacca taaaacgcta tgcagaagga acattatgga gagaaagggt 1900

 actgaggcac tctagaatct gccacattca ttttcaaatg caaatgcaga 1950

 agacttacct tagttcaagg ggaggggaca aagaccccac agcccaacag 2000

 caggactgta gaggtcactc tgactccatc aaacttttta ttgtggccat 2050

 cttaggaaaa tacattctgc ccctgaatga ttctgtctag aaaagctctg 2100

 gagtattgat cactactgga aaaacactta aggagctaaa cttaccttcg 2150

 gggattatta gctgataagg ttcacagttt ctctcaccca ggtgtaactg 2200

 gattttttct ggggcctcaa tccagtcttg ataacagcga ggaaagaggt 2250

 attgaagaaa caggggtggg tttgaagtac tattttcccc agggtggctt 2300

 caatctcccc acctaggatg tcagccctgt ccaaggacct tccctcttct 2350

 cccccagttc cctgggcaat cacttcacct tggacaaagg atcagcacag 2400

 ctggcctcca gatccacatc accactcttc cactcgattg ttcccagatc 2450

 ctccctgcct ggcctgctca gaggttccct gttggtaacc tggctttatc 2500

 aaattctcat ccctttccca cacccacttc tctcctatca ccttccccca 2550

 agattacctg aacagggtcc atggccactc aacctgtcag cttgcaccat 2600

 ccccacctgc cacctacagt caggccacat gcctggtcac tgaatcatgc 2650

 aaaactggcc tcagtcccta aaaatgatgt ggaaaggaaa gcccaggatc 2700

 tgacaatgag ccctggtgga tttgtgggga aaaaatacac agcactcccc 2750

 acctttcttt cgttcatctc cagggcccca cctcagatca aagcagctct 2800

 ggatgagatg ggacctgcag ctctccctcc acaaggtgac tcttagcaac 2850

 ctcatttcga cagtggtttg tagcgtggtg caccagggcc ttgttgaaca 2900

 gatccacact gctctaataa agttcccatc cttaatgact cacttgtcaa 2950

 ctagtggact aattaaccct ccaccaaaaa aacacaaagt gcttctgtga 3000

 gaccaatttt gtgctaatga gcattgagac tgatgctttg taagtcacac 3050

 cacaacaaat attgattgag ggcgctgcat gtgctgggta catttcttgg 3100

 cacttgggaa tcagtagtca agcgaaaccc ttgcctttga gagtttatgg 3150

 tctggataat ataaataaac aagtaagcat aaaaaaaaaa aaaaaaa 3197

<210> 3404
<211> 285
<212> PRT
<213> Homo sapien

<400> 3404
 Met Val Met Arg Pro Leu Trp Ser Leu Leu Leu Trp Glu Ala Leu
   1               5                  10                  15

 Leu Pro Ile Thr Val Thr Gly Ala Gln Val Leu Ser Lys Val Gly
                  20                  25                  30

 Gly Ser Val Leu Leu Val Ala Ala Arg Pro Pro Gly Phe Gln Val
                  35                  40                  45

 Arg Glu Ala Ile Trp Arg Ser Leu Trp Pro Ser Glu Glu Leu Leu
                  50                  55                  60

 Ala Thr Phe Phe Arg Gly Ser Leu Glu Thr Leu Tyr His Ser Arg
                  65                  70                  75

 Phe Leu Gly Arg Ala Gln Leu His Ser Asn Leu Ser Leu Glu Leu
                  80                  85                  90

 Gly Pro Leu Glu Ser Gly Asp Ser Gly Asn Phe Ser Val Leu Met
                  95                 100                 105

 Val Asp Thr Arg Gly Gln Pro Trp Thr Gln Thr Leu Gln Leu Lys
                 110                 115                 120

 Val Tyr Asp Ala Val Pro Arg Pro Val Val Gln Val Phe Ile Ala
                 125                 130                 135

 Val Glu Arg Asp Ala Gln Pro Ser Lys Thr Cys Gln Val Phe Leu
                 140                 145                 150

 Ser Cys Trp Ala Pro Asn Ile Ser Glu Ile Thr Tyr Ser Trp Arg
                 155                 160                 165

 Arg Glu Thr Thr Met Asp Phe Gly Met Glu Pro His Ser Leu Phe
                 170                 175                 180

 Thr Asp Gly Gln Val Leu Ser Ile Ser Leu Gly Pro Gly Asp Arg
                 185                 190                 195

 Asp Val Ala Tyr Ser Cys Ile Val Ser Asn Pro Val Ser Trp Asp
                 200                 205                 210

 Leu Ala Thr Val Thr Pro Trp Asp Ser Cys His His Glu Ala Ala
                 215                 220                 225

 Pro Gly Lys Ala Ser Tyr Lys Asp Val Leu Leu Val Val Val Pro
                 230                 235                 240

 Val Ser Leu Leu Leu Met Leu Val Thr Leu Phe Ser Ala Trp His
                 245                 250                 255

 Trp Cys Pro Cys Ser Gly Lys Lys Lys Lys Asp Val His Ala Asp
                 260                 265                 270

 Arg Val Gly Pro Glu Thr Glu Asn Pro Leu Val Gln Asp Leu Pro
                 275                 280                 285

<210> 3405
<211> 1665
<212> DNA
<213> Homo sapien

<400> 3405
 cgggccctgc gggcgcgggg ctgaaggcgg aaccacgacg ggcagagagc 50

 acggagccgg gaagcccctg ggcgcccgtc ggagggctat ggagcagcgg 100

 ccgcggggct gcgcggcggt ggcggcggcg ctcctcctgg tgctgctggg 150

 ggcccgggcc cagggcggca ctcgtagccc caggtgtgac tgtgccggtg 200

 acttccacaa gaagattggt ctgttttgtt gcagaggctg cccagcgggg 250

 cactacctga aggccccttg cacggagccc tgcggcaact ccacctgcct 300

 tgtgtgtccc caagacacct tcttggcctg ggagaaccac cataattctg 350

 aatgtgcccg ctgccaggcc tgtgatgagc aggcctccca ggtggcgctg 400

 gagaactgtt cagcagtggc cgacacccgc tgtggctgta agccaggctg 450

 gtttgtggag tgccaggtca gccaatgtgt cagcagttca cccttctact 500

 gccaaccatg cctagactgc ggggccctgc accgccacac acggctactc 550

 tgttcccgca gagatactga ctgtgggacc tgcctgcctg gcttctatga 600

 acatggcgat ggctgcgtgt cctgccccac gccacccccg tcccttgcag 650

 gagcaccctg gggagctgtc cagagcgctg tgccgctgtc tgtggctgga 700

 ggcagagtag gtgtgttctg ggtccaggtg ctcctggctg gccttgtggt 750

 ccccctcctg cttggggcca ccctgaccta cacataccgc cactgctggc 800

 ctcacaagcc cctggttact gcagatgaag ctgggatgga ggctctgacc 850

 ccaccaccgg ccacccatct gtcacccttg gacagcgccc acacccttct 900

 agcacctcct gacagcagtg agaagatctg caccgtccag ttggtgggta 950

 acagctggac ccctggctac cccgagaccc aggaggcgct ctgcccgcag 1000

 gtgacatggt cctgggacca gttgcccagc agagctcttg gccccgctgc 1050

 tgcgcccaca ctctcgccag agtccccagc cggctcgcca gccatgatgc 1100

 tgcagccggg cccgcagctc tacgacgtga tggacgcggt cccagcgcgg 1150

 cgctggaagg agttcgtgcg cacgctgggg ctgcgcgagg cagagatcga 1200

 agccgtggag gtggagatcg gccgcttccg agaccagcag tacgagatgc 1250

 tcaagcgctg gcgccagcag cagcccgcgg gcctcggagc cgtttacgcg 1300

 gccctggagc gcatggggct ggacggctgc gtggaagact tgcgcagccg 1350

 cctgcagcgc ggcccgtgac acggcgccca cttgccacct aggcgctctg 1400

 gtggcccttg cagaagccct aagtacggtt acttatgcgt gtagacattt 1450

 tatgtcactt attaagccgc tggcacggcc ctgcgtagca gcaccagccg 1500

 gccccacccc tgctcgcccc tatcgctcca gccaaggcga agaagcacga 1550

 acgaatgtcg agagggggtg aagacatttc tcaacttctc ggccggagtt 1600

 tggctgagat cgcggtatta aatctgtgaa agaaaacaaa acaaaacaaa 1650

 aaaaaaaaaa aaaaa 1665

<210> 3406
<211> 426
<212> PRT
<213> Homo sapien

<400> 3406
 Met Glu Gln Arg Pro Arg Gly Cys Ala Ala Val Ala Ala Ala Leu
   1               5                  10                  15

 Leu Leu Val Leu Leu Gly Ala Arg Ala Gln Gly Gly Thr Arg Ser
                  20                  25                  30

 Pro Arg Cys Asp Cys Ala Gly Asp Phe His Lys Lys Ile Gly Leu
                  35                  40                  45

 Phe Cys Cys Arg Gly Cys Pro Ala Gly His Tyr Leu Lys Ala Pro
                  50                  55                  60

 Cys Thr Glu Pro Cys Gly Asn Ser Thr Cys Leu Val Cys Pro Gln
                  65                  70                  75

 Asp Thr Phe Leu Ala Trp Glu Asn His His Asn Ser Glu Cys Ala
                  80                  85                  90

 Arg Cys Gln Ala Cys Asp Glu Gln Ala Ser Gln Val Ala Leu Glu
                  95                 100                 105

 Asn Cys Ser Ala Val Ala Asp Thr Arg Cys Gly Cys Lys Pro Gly
                 110                 115                 120

 Trp Phe Val Glu Cys Gln Val Ser Gln Cys Val Ser Ser Ser Pro
                 125                 130                 135

 Phe Tyr Cys Gln Pro Cys Leu Asp Cys Gly Ala Leu His Arg His
                 140                 145                 150

 Thr Arg Leu Leu Cys Ser Arg Arg Asp Thr Asp Cys Gly Thr Cys
                 155                 160                 165

 Leu Pro Gly Phe Tyr Glu His Gly Asp Gly Cys Val Ser Cys Pro
                 170                 175                 180

 Thr Pro Pro Pro Ser Leu Ala Gly Ala Pro Trp Gly Ala Val Gln
                 185                 190                 195

 Ser Ala Val Pro Leu Ser Val Ala Gly Gly Arg Val Gly Val Phe
                 200                 205                 210

 Trp Val Gln Val Leu Leu Ala Gly Leu Val Val Pro Leu Leu Leu
                 215                 220                 225

 Gly Ala Thr Leu Thr Tyr Thr Tyr Arg His Cys Trp Pro His Lys
                 230                 235                 240

 Pro Leu Val Thr Ala Asp Glu Ala Gly Met Glu Ala Leu Thr Pro
                 245                 250                 255

 Pro Pro Ala Thr His Leu Ser Pro Leu Asp Ser Ala His Thr Leu
                 260                 265                 270

 Leu Ala Pro Pro Asp Ser Ser Glu Lys Ile Cys Thr Val Gln Leu
                 275                 280                 285

 Val Gly Asn Ser Trp Thr Pro Gly Tyr Pro Glu Thr Gln Glu Ala
                 290                 295                 300

 Leu Cys Pro Gln Val Thr Trp Ser Trp Asp Gln Leu Pro Ser Arg
                 305                 310                 315

 Ala Leu Gly Pro Ala Ala Ala Pro Thr Leu Ser Pro Glu Ser Pro
                 320                 325                 330

 Ala Gly Ser Pro Ala Met Met Leu Gln Pro Gly Pro Gln Leu Tyr
                 335                 340                 345

 Asp Val Met Asp Ala Val Pro Ala Arg Arg Trp Lys Glu Phe Val
                 350                 355                 360

 Arg Thr Leu Gly Leu Arg Glu Ala Glu Ile Glu Ala Val Glu Val
                 365                 370                 375

 Glu Ile Gly Arg Phe Arg Asp Gln Gln Tyr Glu Met Leu Lys Arg
                 380                 385                 390

 Trp Arg Gln Gln Gln Pro Ala Gly Leu Gly Ala Val Tyr Ala Ala
                 395                 400                 405

 Leu Glu Arg Met Gly Leu Asp Gly Cys Val Glu Asp Leu Arg Ser
                 410                 415                 420

 Arg Leu Gln Arg Gly Pro
                 425

<210> 3407
<211> 1149
<212> DNA
<213> Homo sapien

<400> 3407
 ccgcagccat gaccccgcag cttctcctgg cccttgtcct ctgggccagc 50

 tgcccgccct gcagtggaag gaaagggccc ccagcagctc tgacactgcc 100

 ccgggtgcaa tgccgagcct ctcggtaccc gatcgccgtg gattgctcct 150

 ggaccctgcc gcctgctcca aactccacca gccccgtgtc cttcattgcc 200

 acgtacaggc tcggcatggc tgcccggggc cacagctggc cctgcctgca 250

 gcagacgcca acgtccacca gctgcaccat cacggatgtc cagctgttct 300

 ccatggctcc ctacgtgctc aatgtcaccg ccgtccaccc ctggggctcc 350

 agcagcagct tcgtgccttt cataacagag cacatcatca agcccgaccc 400

 tccagaaggc gtgcgcctaa gccccctcgc tgagcgccag ctacaggtgc 450

 agtgggagcc tcccgggtcc tggcccttcc cagagatctt ctcactgaag 500

 tactggatcc gttacaagcg tcagggagct gcgcgcttcc accgggtggg 550

 gcccattgaa gccacgtcct tcatcctcag ggctgtgcgg ccccgagcca 600

 ggtactacgt ccaagtggcg gctcaggacc tcacagacta cggggaactg 650

 agtgactgga gtctccccgc cactgccaca atgagcctgg gcaagtagca 700

 agggcttccc gctgcctcca gacagcacct gggtcctcgc caccctaagc 750

 cccgggacac ctgttggagg gcggatggga tctgcctagc ctgggctgga 800

 gtccttgctt tgctgctgct gagctgccgg gcaacctcag atgaccgact 850

 tttccctttg agcctcagtt tctctagctg agaaatggag atgtactact 900

 ctctccttta cctttacctt taccacagtg cagggctgac tgaactgtca 950

 ctgtgagata ttttttattg tttaattaga aaagaattgt tgttgggctg 1000

 ggcgcagtgg atcgcacctg taatcccagt cactgggaag ccgacgtggg 1050

 agggtagctt gaggccagga gctcgaaacc agtccgggcc acacagcaag 1100

 accccatctc taaaaaatta atataaatat aaaataaaaa aaaaaaaaa 1149

<210> 3408
<211> 229
<212> PRT
<213> Homo sapien

<400> 3408
 Met Thr Pro Gln Leu Leu Leu Ala Leu Val Leu Trp Ala Ser Cys
   1               5                  10                  15

 Pro Pro Cys Ser Gly Arg Lys Gly Pro Pro Ala Ala Leu Thr Leu
                  20                  25                  30

 Pro Arg Val Gln Cys Arg Ala Ser Arg Tyr Pro Ile Ala Val Asp
                  35                  40                  45

 Cys Ser Trp Thr Leu Pro Pro Ala Pro Asn Ser Thr Ser Pro Val
                  50                  55                  60

 Ser Phe Ile Ala Thr Tyr Arg Leu Gly Met Ala Ala Arg Gly His
                  65                  70                  75

 Ser Trp Pro Cys Leu Gln Gln Thr Pro Thr Ser Thr Ser Cys Thr
                  80                  85                  90

 Ile Thr Asp Val Gln Leu Phe Ser Met Ala Pro Tyr Val Leu Asn
                  95                 100                 105

 Val Thr Ala Val His Pro Trp Gly Ser Ser Ser Ser Phe Val Pro
                 110                 115                 120

 Phe Ile Thr Glu His Ile Ile Lys Pro Asp Pro Pro Glu Gly Val
                 125                 130                 135

 Arg Leu Ser Pro Leu Ala Glu Arg Gln Leu Gln Val Gln Trp Glu
                 140                 145                 150

 Pro Pro Gly Ser Trp Pro Phe Pro Glu Ile Phe Ser Leu Lys Tyr
                 155                 160                 165

 Trp Ile Arg Tyr Lys Arg Gln Gly Ala Ala Arg Phe His Arg Val
                 170                 175                 180

 Gly Pro Ile Glu Ala Thr Ser Phe Ile Leu Arg Ala Val Arg Pro
                 185                 190                 195

 Arg Ala Arg Tyr Tyr Val Gln Val Ala Ala Gln Asp Leu Thr Asp
                 200                 205                 210

 Tyr Gly Glu Leu Ser Asp Trp Ser Leu Pro Ala Thr Ala Thr Met
                 215                 220                 225

 Ser Leu Gly Lys


<210> 3409
<211> 1700
<212> DNA
<213> Homo sapien

<400> 3409
 cggaattggt gggttcttgg tctcactgag ttctagaatg aagctgcaga 50

 ccctcgcagt gagtgttaca gctcttaagg ctctctgact gccacccctg 100

 cctgcctgcc cggccctgca caacatgcag ccctccggcc tcgagggtcc 150

 cggcacgttt ggtcggtggc ctctgctgag tctgctgctc ctgctgctgc 200

 tgctccagcc tgtaacctgt gcctacacca cgccaggccc ccccagagcc 250

 ctcaccacgc tgggcgcccc cagagcccac accatgccgg gcacctacgc 300

 tccctcgacc acactcagta gtcccagcac ccagggcctg caagagcagg 350

 cacgggccct gatgcgggac ttcccgctcg tggacggcca caacgacctg 400

 cccctggtcc taaggcaggt ttaccagaaa gggctacagg atgttaacct 450

 gcgcaatttc agctacggcc agaccagcct ggacaggctt agagatggcc 500

 tcgtgggcgc ccagttctgg tcagcctatg tgccatgcca gacccaggac 550

 cgggatgccc tgcgcctcac cctggagcag attgacctca tacgccgcat 600

 gtgtgcctcc tattctgagc tggagcttgt gacctcggct aaagctctga 650

 acgacactca gaaattggcc tgcctcatcg gtgtagaggg tggccactcg 700

 ctggacaata gcctctccat cttacgtacc ttctacatgc tgggagtgcg 750

 ctacctgacg ctcacccaca cctgcaacac accctgggca gagagctccg 800

 ctaagggcgt ccactccttc tacaacaaca tcagcgggct gactgacttt 850

 ggtgagaagg tggtggcaga aatgaaccgc ctgggcatga tggtagactt 900

 atcccatgtc tcagatgctg tggcacggcg ggccctggaa gtgtcacagg 950

 cacctgtgat cttctcccac tcggctgccc ggggtgtgtg caacagtgct 1000

 cggaatgttc ctgatgacat cctgcagctt ctgaagaaga acggtggcgt 1050

 cgtgatggtg tctttgtcca tgggagtaat acagtgcaac ccatcagcca 1100

 atgtgtccac tgtggcagat cacttcgacc acatcaaggc tgtcattgga 1150

 tccaagttca tcgggattgg tggagattat gatggggccg gcaaattccc 1200

 tcaggggctg gaagacgtgt ccacataccc ggtcctgata gaggagttgc 1250

 tgagtcgtgg ctggagtgag gaagagcttc agggtgtcct tcgtggaaac 1300

 ctgctgcggg tcttcagaca agtggaaaag gtacaggaag aaaacaaatg 1350

 gcaaagcccc ttggaggaca agttcccgga tgagcagctg agcagttcct 1400

 gccactccga cctctcacgt ctgcgtcaga gacagagtct gacttcaggc 1450

 caggaactca ctgagattcc catacactgg acagccaagt taccagccaa 1500

 gtggtcagtc tcagagtcct ccccccacat ggccccagtc cttgcagttg 1550

 tggccacctt cccagtcctt attctgtggc tctgatgacc cagttagtcc 1600

 tgccagatgt cactgtagca agccacagac accccacaaa gttcccctgt 1650

 tgtgcaggca caaatatttc ttgaaataaa tgttttggac atagaaaaaa 1700

<210> 3410
<211> 486
<212> PRT
<213> Homo sapien

<400> 3410
 Met Gln Pro Ser Gly Leu Glu Gly Pro Gly Thr Phe Gly Arg Trp
   1               5                  10                  15

 Pro Leu Leu Ser Leu Leu Leu Leu Leu Leu Leu Leu Gln Pro Val
                  20                  25                  30

 Thr Cys Ala Tyr Thr Thr Pro Gly Pro Pro Arg Ala Leu Thr Thr
                  35                  40                  45

 Leu Gly Ala Pro Arg Ala His Thr Met Pro Gly Thr Tyr Ala Pro
                  50                  55                  60

 Ser Thr Thr Leu Ser Ser Pro Ser Thr Gln Gly Leu Gln Glu Gln
                  65                  70                  75

 Ala Arg Ala Leu Met Arg Asp Phe Pro Leu Val Asp Gly His Asn
                  80                  85                  90

 Asp Leu Pro Leu Val Leu Arg Gln Val Tyr Gln Lys Gly Leu Gln
                  95                 100                 105

 Asp Val Asn Leu Arg Asn Phe Ser Tyr Gly Gln Thr Ser Leu Asp
                 110                 115                 120

 Arg Leu Arg Asp Gly Leu Val Gly Ala Gln Phe Trp Ser Ala Tyr
                 125                 130                 135

 Val Pro Cys Gln Thr Gln Asp Arg Asp Ala Leu Arg Leu Thr Leu
                 140                 145                 150

 Glu Gln Ile Asp Leu Ile Arg Arg Met Cys Ala Ser Tyr Ser Glu
                 155                 160                 165

 Leu Glu Leu Val Thr Ser Ala Lys Ala Leu Asn Asp Thr Gln Lys
                 170                 175                 180

 Leu Ala Cys Leu Ile Gly Val Glu Gly Gly His Ser Leu Asp Asn
                 185                 190                 195

 Ser Leu Ser Ile Leu Arg Thr Phe Tyr Met Leu Gly Val Arg Tyr
                 200                 205                 210

 Leu Thr Leu Thr His Thr Cys Asn Thr Pro Trp Ala Glu Ser Ser
                 215                 220                 225

 Ala Lys Gly Val His Ser Phe Tyr Asn Asn Ile Ser Gly Leu Thr
                 230                 235                 240

 Asp Phe Gly Glu Lys Val Val Ala Glu Met Asn Arg Leu Gly Met
                 245                 250                 255

 Met Val Asp Leu Ser His Val Ser Asp Ala Val Ala Arg Arg Ala
                 260                 265                 270

 Leu Glu Val Ser Gln Ala Pro Val Ile Phe Ser His Ser Ala Ala
                 275                 280                 285

 Arg Gly Val Cys Asn Ser Ala Arg Asn Val Pro Asp Asp Ile Leu
                 290                 295                 300

 Gln Leu Leu Lys Lys Asn Gly Gly Val Val Met Val Ser Leu Ser
                 305                 310                 315

 Met Gly Val Ile Gln Cys Asn Pro Ser Ala Asn Val Ser Thr Val
                 320                 325                 330

 Ala Asp His Phe Asp His Ile Lys Ala Val Ile Gly Ser Lys Phe
                 335                 340                 345

 Ile Gly Ile Gly Gly Asp Tyr Asp Gly Ala Gly Lys Phe Pro Gln
                 350                 355                 360

 Gly Leu Glu Asp Val Ser Thr Tyr Pro Val Leu Ile Glu Glu Leu
                 365                 370                 375

 Leu Ser Arg Gly Trp Ser Glu Glu Glu Leu Gln Gly Val Leu Arg
                 380                 385                 390

 Gly Asn Leu Leu Arg Val Phe Arg Gln Val Glu Lys Val Gln Glu
                 395                 400                 405

 Glu Asn Lys Trp Gln Ser Pro Leu Glu Asp Lys Phe Pro Asp Glu
                 410                 415                 420

 Gln Leu Ser Ser Ser Cys His Ser Asp Leu Ser Arg Leu Arg Gln
                 425                 430                 435

 Arg Gln Ser Leu Thr Ser Gly Gln Glu Leu Thr Glu Ile Pro Ile
                 440                 445                 450

 His Trp Thr Ala Lys Leu Pro Ala Lys Trp Ser Val Ser Glu Ser
                 455                 460                 465

 Ser Pro His Met Ala Pro Val Leu Ala Val Val Ala Thr Phe Pro
                 470                 475                 480

 Val Leu Ile Leu Trp Leu
                 485

<210> 3411
<211> 2793
<212> DNA
<213> Homo sapien

<400> 3411
 caggtccccc agaccatccg aaccagccgc ccatgatgac ctgcgagaga 50

 ctcccatgcc ccactgcagg cctgggcccc ctcagggagg aagcgatgaa 100

 gccaggggca gcctccagtc ccttgcagca ggtccccgcc ccgccactgc 150

 ctgcgaagaa gaaccttccc actgcccctc ccagacgccg cgtttccgag 200

 agggtgtcct tagaagacca aagtccgggg atggcggcag agggggacca 250

 gctcagcctg cctccccaag ggacctcaga cggccctgag gacacgcccc 300

 gggagagcac ggagcaaggc caggacacag aggtgaaagc cagcgatcct 350

 cacagcatgc cagagctgcc caggacagcc aaacaacccc cagtcccgcc 400

 ccccaggaaa aaacggatct ctcgacaact ggcctcgacc ctcccagctc 450

 ccttagagaa cgctgagctc tgcacacagg cgatggcctt ggagacaccc 500

 acgccgggtc cacccagaga gggccaaagc cctgcttctc aggctgggac 550

 tcagcaccct cctgcccagg ccactgccca ttcccagagc tctccagagt 600

 tcaagggctc cctggcctcc ctctcagaca gcttgggggt gtctgtcatg 650

 gccaccgacc aggactccta ctccaccagc agcacggagg aggagctgga 700

 gcagttcagc agccccagcg tgaagaagaa gccctccatg atcctgggca 750

 aggctcggca ccggctgagc tttgccagtt tcagcagcat gttccacgct 800

 ttcctctcca acaaccgcaa gctgtacaag aaggtggtgg agctggcgca 850

 ggacaagggc tcgtactttg gcagcctggt gcaggactac aaggtgtaca 900

 gcctggagat gatggcgcgc cagacctcca gcacggagat gctgcaggag 950

 attcgcacca tgatgaccca gctcaagagc tacctgctgc agagcaccga 1000

 gctcaaggcc ctggtggacc ccgccctgca ctccgaggag gagctcgaag 1050

 caattgtaga gtctgccttg tacaaatgtg tcctgaagcc cctgaaggaa 1100

 gccatcaact catgcctgca tcagatccac agcaaggatg gttcgctgca 1150

 gcagctcaag gagaaccagt tagtgatcct ggccaccacc accactgacc 1200

 taggtgtgac caccagcgtg ccggaggtgc ccatgatgga gaagttcctg 1250

 cagaagttca ccagcatgca caaggcctac tcacctgaga agaagatctc 1300

 catcctgctc aagacctgca aactcatcta cgactccatg gccctcggca 1350

 acccagggaa gccctatggg gcggatgact tcctgcctgt gctcatgtat 1400

 gtgctggccc gcagcaacct cacggagatg cttctcaatg tggagtacat 1450

 gatggagctc atggaccccg ccctgcagct gggggagggt tcctactatc 1500

 tgaccaccac ctacggggcc ctggagcaca tcaagagcta cgacaagatc 1550

 acggtgaccc ggcagctgag tgtggaggtg caggactcca tccaccgctg 1600

 ggagcgccgg cgtactctca acaaggcccg ggcctcccgc tcctccgtac 1650

 aggacttcat ctgcgtgtcg tacctggagc ccgagcagca ggcgcggacg 1700

 ctggcgtcgc gggcggacac ccaggcccag gcgctgtgcg cgcagtgcgc 1750

 ggagaagttc gcggtggagc ggccgcaggc gcaccggctg ttcgtgctgg 1800

 tggacgggcg ctgcttccag ctggcggacg acgcgctgcc gcactgcatc 1850

 aagggctacc tgctgcgcag cgagcccaag cgcgacttcc actttgtcta 1900

 ccggcccctg gacggtggtg gcggcggcgg cgggagcccg ccctgcctgg 1950

 tggtgcggga gcccaacttc ctgtgaggcc ctcccggggc gcctcccctc 2000

 acccccaggc gcacgtctgg ccccgcctct ggctgcgcac tcccgaccgc 2050

 gacgtccacg cagcagaggg acatgggcca ttccatgacg tgcccaggcc 2100

 aacgtcgcag gacagttgtg aaaataacat gacgctcgtc caaggccact 2150

 tcctgagggc aagtcctaat agccctgaga caccgagacg gcatgttctt 2200

 cattagacgg aaagggaaac tgaggctcag gagagaggcg ctccaggccg 2250

 ctgcagccaa caaaccggcg ccctcttcac acgtagctcc tcaggccatt 2300

 ccccatgagt cccccacacc caccccatcc tcggtctttg caaagaaggg 2350

 cccgagctta gtttccccag gactggccta ggaaggagca ccggccacag 2400

 ctgctccccg tgccactcag ggtggaccca gcatctcagg agcacctcag 2450

 ggtgtcggtt aagagacagg cctccacccc tgcaccagag cctgctctta 2500

 gctcccggtg cccccagacc ccgcagctct gtgcccggca agaagcagct 2550

 agacacacgc cagggcgcca agcacggcca gctccgcgga cccatggaca 2600

 agcccagccc cgcctcaggg aaaacagggc ctttccctac aggacacgcc 2650

 ccagagctgt ggcagattgc aggagccatc gtgtggggag aatttaataa 2700

 aagccctttt gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2793

<210> 3412
<211> 497
<212> PRT
<213> Homo sapien

<400> 3412
 Met Ala Leu Glu Thr Pro Thr Pro Gly Pro Pro Arg Glu Gly Gln
   1               5                  10                  15

 Ser Pro Ala Ser Gln Ala Gly Thr Gln His Pro Pro Ala Gln Ala
                  20                  25                  30

 Thr Ala His Ser Gln Ser Ser Pro Glu Phe Lys Gly Ser Leu Ala
                  35                  40                  45

 Ser Leu Ser Asp Ser Leu Gly Val Ser Val Met Ala Thr Asp Gln
                  50                  55                  60

 Asp Ser Tyr Ser Thr Ser Ser Thr Glu Glu Glu Leu Glu Gln Phe
                  65                  70                  75

 Ser Ser Pro Ser Val Lys Lys Lys Pro Ser Met Ile Leu Gly Lys
                  80                  85                  90

 Ala Arg His Arg Leu Ser Phe Ala Ser Phe Ser Ser Met Phe His
                  95                 100                 105

 Ala Phe Leu Ser Asn Asn Arg Lys Leu Tyr Lys Lys Val Val Glu
                 110                 115                 120

 Leu Ala Gln Asp Lys Gly Ser Tyr Phe Gly Ser Leu Val Gln Asp
                 125                 130                 135

 Tyr Lys Val Tyr Ser Leu Glu Met Met Ala Arg Gln Thr Ser Ser
                 140                 145                 150

 Thr Glu Met Leu Gln Glu Ile Arg Thr Met Met Thr Gln Leu Lys
                 155                 160                 165

 Ser Tyr Leu Leu Gln Ser Thr Glu Leu Lys Ala Leu Val Asp Pro
                 170                 175                 180

 Ala Leu His Ser Glu Glu Glu Leu Glu Ala Ile Val Glu Ser Ala
                 185                 190                 195

 Leu Tyr Lys Cys Val Leu Lys Pro Leu Lys Glu Ala Ile Asn Ser
                 200                 205                 210

 Cys Leu His Gln Ile His Ser Lys Asp Gly Ser Leu Gln Gln Leu
                 215                 220                 225

 Lys Glu Asn Gln Leu Val Ile Leu Ala Thr Thr Thr Thr Asp Leu
                 230                 235                 240

 Gly Val Thr Thr Ser Val Pro Glu Val Pro Met Met Glu Lys Phe
                 245                 250                 255

 Leu Gln Lys Phe Thr Ser Met His Lys Ala Tyr Ser Pro Glu Lys
                 260                 265                 270

 Lys Ile Ser Ile Leu Leu Lys Thr Cys Lys Leu Ile Tyr Asp Ser
                 275                 280                 285

 Met Ala Leu Gly Asn Pro Gly Lys Pro Tyr Gly Ala Asp Asp Phe
                 290                 295                 300

 Leu Pro Val Leu Met Tyr Val Leu Ala Arg Ser Asn Leu Thr Glu
                 305                 310                 315

 Met Leu Leu Asn Val Glu Tyr Met Met Glu Leu Met Asp Pro Ala
                 320                 325                 330

 Leu Gln Leu Gly Glu Gly Ser Tyr Tyr Leu Thr Thr Thr Tyr Gly
                 335                 340                 345

 Ala Leu Glu His Ile Lys Ser Tyr Asp Lys Ile Thr Val Thr Arg
                 350                 355                 360

 Gln Leu Ser Val Glu Val Gln Asp Ser Ile His Arg Trp Glu Arg
                 365                 370                 375

 Arg Arg Thr Leu Asn Lys Ala Arg Ala Ser Arg Ser Ser Val Gln
                 380                 385                 390

 Asp Phe Ile Cys Val Ser Tyr Leu Glu Pro Glu Gln Gln Ala Arg
                 395                 400                 405

 Thr Leu Ala Ser Arg Ala Asp Thr Gln Ala Gln Ala Leu Cys Ala
                 410                 415                 420

 Gln Cys Ala Glu Lys Phe Ala Val Glu Arg Pro Gln Ala His Arg
                 425                 430                 435

 Leu Phe Val Leu Val Asp Gly Arg Cys Phe Gln Leu Ala Asp Asp
                 440                 445                 450

 Ala Leu Pro His Cys Ile Lys Gly Tyr Leu Leu Arg Ser Glu Pro
                 455                 460                 465

 Lys Arg Asp Phe His Phe Val Tyr Arg Pro Leu Asp Gly Gly Gly
                 470                 475                 480

 Gly Gly Gly Gly Ser Pro Pro Cys Leu Val Val Arg Glu Pro Asn
                 485                 490                 495

 Phe Leu


<210> 3413
<211> 2793
<212> DNA
<213> Homo sapien

<400> 3413
 caggtccccc agaccatccg aaccagccgc ccatgatgac ctgcgagaga 50

 ctcccatgcc ccactgcagg cctgggcccc ctcagggagg aagcgatgaa 100

 gccaggggca gcctccagtc ccttgcagca ggtccccgcc ccgccactgc 150

 ctgcgaagaa gaaccttccc actgcccctc ccagacgccg cgtttccgag 200

 agggtgtcct tagaagacca aagtccgggg atggcggcag agggggacca 250

 gctcagcctg cctccccaag ggacctcaga cggccctgag gacacgcccc 300

 gggagagcac ggagcaaggc caggacacag aggtgaaagc cagcgatcct 350

 cacagcatgc cagagctgcc caggacagcc aaacaacccc cagtcccgcc 400

 ccccaggaaa aaacggatct ctcgacaact ggcctcgacc ctcccagctc 450

 ccttagagaa cgctgagctc tgcacacagg cgatggcctt ggagacaccc 500

 acgccgggtc cacccagaga gggccaaagc cctgcttctc aggctgggac 550

 tcagcaccct cctgcccagg ccactgccca ttcccagagc tctccagagt 600

 tcaagggctc cctggcctcc ctctcagaca gcttgggggt gtctgtcatg 650

 gccaccgacc aggactccta ctccaccagc agcacggagg aggagctgga 700

 gcagttcagc agccccagcg tgaagaagaa gccctccatg atcctgggca 750

 aggctcggca ccggctgagc tttgccagtt tcagcagcat gttccacgct 800

 ttcctctcca acaaccgcaa gctgtacaag aaggtggtgg agctggcgca 850

 ggacaagggc tcgtactttg gcagcctggt gcaggactac aaggtgtaca 900

 gcctggagat gatggcgcgc cagacctcca gcacggagat gctgcaggag 950

 attcgcacca tgatgaccca gctcaagagc tacctgctgc agagcaccga 1000

 gctcaaggcc ctggtggacc ccgccctgca ctccgaggag gagctcgaag 1050

 caattgtaga gtctgccttg tacaaatgtg tcctgaagcc cctgaaggaa 1100

 gccatcaact catgcctgca tcagatccac agcaaggatg gttcgctgca 1150

 gcagctcaag gagaaccagt tagtgatcct ggccaccacc accactgacc 1200

 taggtgtgac caccagcgtg ccggaggtgc ccatgatgga gaagttcctg 1250

 cagaagttca ccagcatgca caaggcctac tcacctgaga agaagatctc 1300

 catcctgctc aagacctgca aactcatcta cgactccatg gccctcggca 1350

 acccagggaa gccctatggg gcggatgact tcctgcctgt gctcatgtat 1400

 gtgctggccc gcagcaacct cacggagatg cttctcaatg tggagtacat 1450

 gatggagctc atggaccccg ccctgcagct gggggagggt tcctactatc 1500

 tgaccaccac ctacggggcc ctggagcaca tcaagagcta cgacaagatc 1550

 acggtgaccc ggcagctgag tgtggaggtg caggactcca tccaccgctg 1600

 ggagcgccgg cgtactctca acaaggcccg ggcctcccgc tcctccgtac 1650

 aggacttcat ctgcgtgtcg tacctggagc ccgagcagca ggcgcggacg 1700

 ctggcgtcgc gggcggacac ccaggcccag gcgctgtgcg cgcagtgcgc 1750

 ggagaagttc gcggtggagc ggccgcaggc gcaccggctg ttcgtgctgg 1800

 tggacgggcg ctgcttccag ctggcggacg acgcgctgcc gcactgcatc 1850

 aagggctacc tgctgcgcag cgagcccaag cgcgacttcc actttgtcta 1900

 ccggcccctg gacggtggtg gcggcggcgg cgggagcccg ccctgcctgg 1950

 tggtgcggga gcccaacttc ctgtgaggcc ctcccggggc gcctcccctc 2000

 acccccaggc gcacgtctgg ccccgcctct ggctgcgcac tcccgaccgc 2050

 gacgtccacg cagcagaggg acatgggcca ttccatgacg tgcccaggcc 2100

 aacgtcgcag gacagttgtg aaaataacat gacgctcgtc caaggccact 2150

 tcctgagggc aagtcctaat agccctgaga caccgagacg gcatgttctt 2200

 cattagacgg aaagggaaac tgaggctcag gagagaggcg ctccaggccg 2250

 ctgcagccaa caaaccggcg ccctcttcac acgtagctcc tcaggccatt 2300

 ccccatgagt cccccacacc caccccatcc tcggtctttg caaagaaggg 2350

 cccgagctta gtttccccag gactggccta ggaaggagca ccggccacag 2400

 ctgctccccg tgccactcag ggtggaccca gcatctcagg agcacctcag 2450

 ggtgtcggtt aagagacagg cctccacccc tgcaccagag cctgctctta 2500

 gctcccggtg cccccagacc ccgcagctct gtgcccggca agaagcagct 2550

 agacacacgc cagggcgcca agcacggcca gctccgcgga cccatggaca 2600

 agcccagccc cgcctcaggg aaaacagggc ctttccctac aggacacgcc 2650

 ccagagctgt ggcagattgc aggagccatc gtgtggggag aatttaataa 2700

 aagccctttt gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2793

<210> 3414
<211> 497
<212> PRT
<213> Homo sapien

<400> 3414
 Met Ala Leu Glu Thr Pro Thr Pro Gly Pro Pro Arg Glu Gly Gln
   1               5                  10                  15

 Ser Pro Ala Ser Gln Ala Gly Thr Gln His Pro Pro Ala Gln Ala
                  20                  25                  30

 Thr Ala His Ser Gln Ser Ser Pro Glu Phe Lys Gly Ser Leu Ala
                  35                  40                  45

 Ser Leu Ser Asp Ser Leu Gly Val Ser Val Met Ala Thr Asp Gln
                  50                  55                  60

 Asp Ser Tyr Ser Thr Ser Ser Thr Glu Glu Glu Leu Glu Gln Phe
                  65                  70                  75

 Ser Ser Pro Ser Val Lys Lys Lys Pro Ser Met Ile Leu Gly Lys
                  80                  85                  90

 Ala Arg His Arg Leu Ser Phe Ala Ser Phe Ser Ser Met Phe His
                  95                 100                 105

 Ala Phe Leu Ser Asn Asn Arg Lys Leu Tyr Lys Lys Val Val Glu
                 110                 115                 120

 Leu Ala Gln Asp Lys Gly Ser Tyr Phe Gly Ser Leu Val Gln Asp
                 125                 130                 135

 Tyr Lys Val Tyr Ser Leu Glu Met Met Ala Arg Gln Thr Ser Ser
                 140                 145                 150

 Thr Glu Met Leu Gln Glu Ile Arg Thr Met Met Thr Gln Leu Lys
                 155                 160                 165

 Ser Tyr Leu Leu Gln Ser Thr Glu Leu Lys Ala Leu Val Asp Pro
                 170                 175                 180

 Ala Leu His Ser Glu Glu Glu Leu Glu Ala Ile Val Glu Ser Ala
                 185                 190                 195

 Leu Tyr Lys Cys Val Leu Lys Pro Leu Lys Glu Ala Ile Asn Ser
                 200                 205                 210

 Cys Leu His Gln Ile His Ser Lys Asp Gly Ser Leu Gln Gln Leu
                 215                 220                 225

 Lys Glu Asn Gln Leu Val Ile Leu Ala Thr Thr Thr Thr Asp Leu
                 230                 235                 240

 Gly Val Thr Thr Ser Val Pro Glu Val Pro Met Met Glu Lys Phe
                 245                 250                 255

 Leu Gln Lys Phe Thr Ser Met His Lys Ala Tyr Ser Pro Glu Lys
                 260                 265                 270

 Lys Ile Ser Ile Leu Leu Lys Thr Cys Lys Leu Ile Tyr Asp Ser
                 275                 280                 285

 Met Ala Leu Gly Asn Pro Gly Lys Pro Tyr Gly Ala Asp Asp Phe
                 290                 295                 300

 Leu Pro Val Leu Met Tyr Val Leu Ala Arg Ser Asn Leu Thr Glu
                 305                 310                 315

 Met Leu Leu Asn Val Glu Tyr Met Met Glu Leu Met Asp Pro Ala
                 320                 325                 330

 Leu Gln Leu Gly Glu Gly Ser Tyr Tyr Leu Thr Thr Thr Tyr Gly
                 335                 340                 345

 Ala Leu Glu His Ile Lys Ser Tyr Asp Lys Ile Thr Val Thr Arg
                 350                 355                 360

 Gln Leu Ser Val Glu Val Gln Asp Ser Ile His Arg Trp Glu Arg
                 365                 370                 375

 Arg Arg Thr Leu Asn Lys Ala Arg Ala Ser Arg Ser Ser Val Gln
                 380                 385                 390

 Asp Phe Ile Cys Val Ser Tyr Leu Glu Pro Glu Gln Gln Ala Arg
                 395                 400                 405

 Thr Leu Ala Ser Arg Ala Asp Thr Gln Ala Gln Ala Leu Cys Ala
                 410                 415                 420

 Gln Cys Ala Glu Lys Phe Ala Val Glu Arg Pro Gln Ala His Arg
                 425                 430                 435

 Leu Phe Val Leu Val Asp Gly Arg Cys Phe Gln Leu Ala Asp Asp
                 440                 445                 450

 Ala Leu Pro His Cys Ile Lys Gly Tyr Leu Leu Arg Ser Glu Pro
                 455                 460                 465

 Lys Arg Asp Phe His Phe Val Tyr Arg Pro Leu Asp Gly Gly Gly
                 470                 475                 480

 Gly Gly Gly Gly Ser Pro Pro Cys Leu Val Val Arg Glu Pro Asn
                 485                 490                 495

 Phe Leu


<210> 3415
<211> 4223
<212> DNA
<213> Homo sapien

<400> 3415
 agtgcatcgg ccccgggtct gtccgggcgt tgcgggattg gggcctggga 50

 acgctcggcc cccggcagcc gagaagcccg tgactgggct gagcagcacc 100

 atcccagccc tggggcctgc tgactgccca gtcccggctt cacctgcagc 150

 gaacccggag cgttgctatc ctccaccgga ctgtcaggct ctgcgcgccc 200

 cgcggaggtc ggcggcgacc agcagcgact gcggagcgac ggcgggcggc 250

 cccgggcatg tacgcccccg gaggcgcagg gctgcccggc gggcgccggc 300

 ggaggagccc gggaggcagc gctctgccca agcagccgga gcgtagcctg 350

 gcctcggccc tgcctggcgc cctgtctatc acggcgctgt gcactgccct 400

 cgccgagccc gcctggttgc acatccacgg aggcacctgt tcgcgccagg 450

 agctgggggt ctccgacgtg ttgggctatg tgcacccgga cctgctgaaa 500

 gatttctgca tgaatcccca gacagtgctg ctcctgcggg tcatcgccgc 550

 cttctgtttc ctgggcatcc tgtgtagtct ctccgctttc cttctggatg 600

 tctttgggcc gaagcatcct gctctgaaga tcactcgtcg ctatgccttc 650

 gcccatatcc taacggttct gcagtgtgcc accgtcattg gcttttctta 700

 ttgggcttct gaactcatct tggcccagca gcagcagcat aagaagtacc 750

 atggatccca ggtctatgtc accttcgccg ttagcttcta cctggtggca 800

 ggagctggtg gagcctcaat cctggccacg gcagccaacc tcctgcgcca 850

 ctaccccaca gaggaagagg agcaggcgct ggagctgctc tcagagatgg 900

 aagagaacga gccctacccg gcggaatatg aggtcatcaa ccagttccag 950

 ccaccccctg cttacacacc ctaatgccag ccctgggctc tcttcctcgg 1000

 cagcccctcc ctcaactctg cagctcctct cgcacccaga ggagctcctt 1050

 tccccagcag gcctcactgg taggatcctg accatcttct ccaaaccttc 1100

 cccaggagag actctgcctt tagggtcatc caagtatccc tgctctcaga 1150

 accggaggtc cactggtttt ctataatgta ctctttccct cctgccacat 1200

 cctgccccct tcacattcac gagtcattac cagccaggga aggtcatcca 1250

 agtttcctcc agcatgggcg atatctttgg gaccgagact ttccttggag 1300

 agctgctgag agcggacagt cccaaaaaca agtgtcaaag ggcccaaggg 1350

 aaaggggact gtgccctgga ggctcacttc acagggatca gtgtttgctc 1400

 cacagctgta gctctgggct gacgcccccc agaccccttc cttctcggag 1450

 tgacccgccc ccaggccacc tgctccgggg agttctgtgc actttactct 1500

 ttggacttct cctcacgtgt gccctggttt tatggggaga gggaatcgct 1550

 gttgggaagg cagagcagtt gcaaccctct ctgcccttgc ttcatgtggc 1600

 tggagcccag gcaaggagag caggagccag cgtgagactg aggccccctg 1650

 gtgcctatca aggaccagag tgaaggggac tacatctccc agcccttcac 1700

 cttttaaata tgagtggttt taaaaggaaa aaagtgaaac caggcaacag 1750

 caacaatatt ctgtttttaa aatagggaca agactgttgt cactttttag 1800

 acatgtatcc cattcctttt ggctctgcaa tatttggggc tgtagctcct 1850

 tccaagccca tggtagtccc tccccgagtc tctcccagta gaatgcagcc 1900

 tcccttccct ggccccttcc ctctcagtga cggtgactcc ctggggcctt 1950

 ctcgtggaac ccagaggggc tgaggactgt ggcctggctg gcgggccagc 2000

 gtggtgctcc tcaggactgc agcactgaga tggaacctgg cctcagttta 2050

 ggaacagggg ccacaacagg gcaggaaccc accaccctcc acataggaat 2100

 acaaccagtg gggccacatc atgtgaggca tcagacccac actgtcagcc 2150

 cagcaggccg ggctgtgtcc ttcagaccct gtgctgccct agactctgac 2200

 tcgggactcc agcttgccac gtgccctctc ccctcttgaa tgtactctgg 2250

 tcttgcagtg tgctgctggg acttccttgc tcagccatca ctctggtcac 2300

 cttgtttgct ctgggtctgg ctgaattttc tgccctgaga tctgggcata 2350

 aagtggatga aacttgaaag accttcagtg tagatccaga tggccaacct 2400

 gtccttgtta agttacttgc ttcttgggaa tcagtgtccc ctgctgagct 2450

 gaaaaggaaa tggattccaa tctcttccaa cctttaaggt gatagatagt 2500

 ttgagcaaga ctggagaatg gacaacacta tgaagctgtg gctagaaagg 2550

 gactgtcatg tcccatcctt tggccagatt gactggggat gtccggacag 2600

 atgcctgcat gggtggtgag ggccacatct gcacacgagc cagtggctgc 2650

 ttgcagttca ctgctgtgat gccagagtgt gttcaaaggt gactctcctg 2700

 ctcttctgga ctcttctctc aggcaagaaa ggctgcaggc tgcctgctat 2750

 gtgatgcctg agcacaaagc caaggaactg aactaagtct ttctgttaag 2800

 tcctgagttt gtcattggca ggtttacttg tggccagctc tctctgccct 2850

 tgggtgtctg agcaggcaga ccagaagacc aggcactgga cctgcatgcc 2900

 aaagggactg gtcatctcct gaggacctgt acatgaccct gtggactgtt 2950

 ccgcacgatc cggaacccac tttttattca ctccccatgt ctttggcctt 3000

 cctcttcttt ctctttccct ctgccatcct gacactgata gtttgtcata 3050

 taaattcccc gggttgtgtt tttttttcta gaaaaaaatt aaaagggaaa 3100

 acaaaaccaa aaaaaccaga aaccacgaat aagaatggaa atgacaatgg 3150

 ctgcctgtca tttttctgtc acgattttcc tgatttggtt tgttcccttt 3200

 gtctcagaga agcaggagat gttgatgagg ctgtattttt ttttcttttt 3250

 cttgtttttg agacaagagt ctcgctctgt cacccgggct ggagtgtaac 3300

 gtggcatgat ctcagctcac tgcaacctct gcctcctggg ttcaagcgat 3350

 tatcctgcct cagcctcctg agtagctggg attacaggca tgcgccacta 3400

 tgcccagata atttttttgt atttttagta gagacagggt ttcaccatgt 3450

 tggccaggct ggtctggaac tcctaacctc aggttatcca cccaccttgg 3500

 cctcccaaag tgctgggatt ataggcatga accaccgtgc ctggccaaag 3550

 atgtaattta aaatagttag gagggacttg gcatgggcca gctccgtgca 3600

 tggcattttc acccccagag cttcctaatc ctgttttcac acaggaagtt 3650

 tctaggtctt tctagaacag ctagaaatag tagctgactc ccgcccaagg 3700

 cccaaccttc aaaccctgag ctcttcaggc tgcatcctct ggtgagctat 3750

 agaggagaac gtggctccta aactctagcc atcctgtggg aggaaataga 3800

 cttctttggg ctgtggcttg cagaacaaac tacacttttt ttccctctat 3850

 tgtttaaatt ttatttaata atttgtgtgt ttttctgtct ttattttctg 3900

 tatttcacgt gttccttcac tccctagaaa ctgcactttc tttgaaacca 3950

 taggtaatga atcttactag gagaggcatg gggatagaga cagttctggg 4000

 agtgtgacct gtaagcctcc tgtagggcag tgccaggcct tgattgccca 4050

 cgttctctcc gttccttctt ccttcataca tttgaccaca cagcctacac 4100

 ccagccccga gtgtgcatca cggtaaaaga gctgagggct ctcttcaggg 4150

 agcagcccat ttaggtctct tttgttgttg ttagggagaa tacacatctt 4200

 tcttggaaaa aaaaaaaaaa aaa 4223

<210> 3416
<211> 238
<212> PRT
<213> Homo sapien

<400> 3416
 Met Tyr Ala Pro Gly Gly Ala Gly Leu Pro Gly Gly Arg Arg Arg
   1               5                  10                  15

 Arg Ser Pro Gly Gly Ser Ala Leu Pro Lys Gln Pro Glu Arg Ser
                  20                  25                  30

 Leu Ala Ser Ala Leu Pro Gly Ala Leu Ser Ile Thr Ala Leu Cys
                  35                  40                  45

 Thr Ala Leu Ala Glu Pro Ala Trp Leu His Ile His Gly Gly Thr
                  50                  55                  60

 Cys Ser Arg Gln Glu Leu Gly Val Ser Asp Val Leu Gly Tyr Val
                  65                  70                  75

 His Pro Asp Leu Leu Lys Asp Phe Cys Met Asn Pro Gln Thr Val
                  80                  85                  90

 Leu Leu Leu Arg Val Ile Ala Ala Phe Cys Phe Leu Gly Ile Leu
                  95                 100                 105

 Cys Ser Leu Ser Ala Phe Leu Leu Asp Val Phe Gly Pro Lys His
                 110                 115                 120

 Pro Ala Leu Lys Ile Thr Arg Arg Tyr Ala Phe Ala His Ile Leu
                 125                 130                 135

 Thr Val Leu Gln Cys Ala Thr Val Ile Gly Phe Ser Tyr Trp Ala
                 140                 145                 150

 Ser Glu Leu Ile Leu Ala Gln Gln Gln Gln His Lys Lys Tyr His
                 155                 160                 165

 Gly Ser Gln Val Tyr Val Thr Phe Ala Val Ser Phe Tyr Leu Val
                 170                 175                 180

 Ala Gly Ala Gly Gly Ala Ser Ile Leu Ala Thr Ala Ala Asn Leu
                 185                 190                 195

 Leu Arg His Tyr Pro Thr Glu Glu Glu Glu Gln Ala Leu Glu Leu
                 200                 205                 210

 Leu Ser Glu Met Glu Glu Asn Glu Pro Tyr Pro Ala Glu Tyr Glu
                 215                 220                 225

 Val Ile Asn Gln Phe Gln Pro Pro Pro Ala Tyr Thr Pro
                 230                 235

<210> 3417
<211> 2082
<212> DNA
<213> Homo sapien

<400> 3417
 cttggctgga acctgagacg gattcgctcc caaatgatgc tccagtggct 50

 ggagcaactc aagttcatca ttgtcctgag agagaggagc agcgcggttc 100

 tcggccggga cagcagaacg ccaggggacc ctcacctggg cgcgccgggg 150

 cacgggcttt gattgtcctg gggtcgcgga gacccgcgcg cctgccctgc 200

 acgccgggcg gcaacctttg cagtcgcgtt ggctgctgcg atcggccggc 250

 gggtccctgc cgaaggctcg gctgcttctg tccacctctt acacttcttc 300

 atttatcggt ggatcatttc gagagtccgt cttgtaaatg tttggcactt 350

 tgctacttta ttgcttcttt ctggcgacag ttccagcact cgccgagacc 400

 ggcggagaaa ggcagctgag cccggagaag agcgaaatat ggggacccgg 450

 gctaaaagca gacgtcgtcc ttcccgcccg ctatttctat attcaggcag 500

 tggatacatc agggaataaa ttcacatctt ctccaggcga aaaggtcttc 550

 caggtgaaag tctcagcacc agaggagcaa ttcactagag ttggagtcca 600

 ggttttagac cgaaaagatg ggtccttcat agtaagatac agaatgtatg 650

 caagctacaa aaatctgaag gtggaagtta aattccaagg gcaacatgtg 700

 gccaaatccc catatatttt aaaagggccg gtttaccatg agaactgtga 750

 ctgtcctctg caagatagtg cagcctggct acgggagatg aactgccctg 800

 aaaccattgc tcagattcag agagatctgg cacatttccc tgctgtggat 850

 ccagaaaaga ttgcagtaga aatcccaaaa agatttggac agaggcagag 900

 cctatgtcac tacaccttaa aggataacaa ggtttatatc aagactcatg 950

 gtgaacatgt aggttttaga attttcatgg atgccatact actttctttg 1000

 actagaaagg tgaagatgcc agatgtggag ctctttgtta atttgggaga 1050

 ctggcctttg gaaaaaaaga aatccaattc aaacatccat ccgatctttt 1100

 cctggtgtgg ctccacagat tccaaggata tcgtgatgcc tacgtacgat 1150

 ttgactgatt ctgttctgga aaccatgggc cgggtaagtc tggatatgat 1200

 gtccgtgcaa gctaacacgg gtcctccctg ggaaagcaaa aattccactg 1250

 ccgtctggag agggcgagac agccgcaaag agagactcga gctggttaaa 1300

 ctcagtagaa aacacccaga actcatagac gctgctttca ccaacttttt 1350

 cttctttaaa cacgatgaaa acctgtatgg tcccattgtg aaacatattt 1400

 cattttttga tttcttcaag cataagtatc aaataaatat cgatggcact 1450

 gtagcagctt atcgcctgcc atatttgcta gttggtgaca gtgttgtgct 1500

 gaagcaggat tccatctact atgaacattt ttacaatgag ctgcagccct 1550

 ggaaacacta cattccagtt aagagcaacc tgagcgatct gctagaaaaa 1600

 cttaaatggg cgaaagatca cgatgaagag gccaaaaaga tagcaaaagc 1650

 aggacaagaa tttgcaagaa ataatctcat gggcgatgac atattctgtt 1700

 attatttcaa acttttccag gaatatgcca atttacaagt gagtgagccc 1750

 caaatccgag agggcatgaa aagggtagaa ccacagactg aggacgacct 1800

 cttcccttgt acttgccata ggaaaaagac caaagatgaa ctctgatatg 1850

 caaaataact tctattagaa taatggtgct ctgaagactc ttcttaacta 1900

 aaaagaagaa tttttttaag tattaattcc atggacaata taaaatctgt 1950

 gtgattgttt gcagtatgaa gacacatttc tacttatgca gtattctcat 2000

 gactgtactt taaagtacat ttttagaatt ttataataaa accaccttta 2050

 ttttaaagga aaaaaaaaaa aaaaaaaaaa aa 2082

<210> 3418
<211> 502
<212> PRT
<213> Homo sapien

<400> 3418
 Met Phe Gly Thr Leu Leu Leu Tyr Cys Phe Phe Leu Ala Thr Val
   1               5                  10                  15

 Pro Ala Leu Ala Glu Thr Gly Gly Glu Arg Gln Leu Ser Pro Glu
                  20                  25                  30

 Lys Ser Glu Ile Trp Gly Pro Gly Leu Lys Ala Asp Val Val Leu
                  35                  40                  45

 Pro Ala Arg Tyr Phe Tyr Ile Gln Ala Val Asp Thr Ser Gly Asn
                  50                  55                  60

 Lys Phe Thr Ser Ser Pro Gly Glu Lys Val Phe Gln Val Lys Val
                  65                  70                  75

 Ser Ala Pro Glu Glu Gln Phe Thr Arg Val Gly Val Gln Val Leu
                  80                  85                  90

 Asp Arg Lys Asp Gly Ser Phe Ile Val Arg Tyr Arg Met Tyr Ala
                  95                 100                 105

 Ser Tyr Lys Asn Leu Lys Val Glu Val Lys Phe Gln Gly Gln His
                 110                 115                 120

 Val Ala Lys Ser Pro Tyr Ile Leu Lys Gly Pro Val Tyr His Glu
                 125                 130                 135

 Asn Cys Asp Cys Pro Leu Gln Asp Ser Ala Ala Trp Leu Arg Glu
                 140                 145                 150

 Met Asn Cys Pro Glu Thr Ile Ala Gln Ile Gln Arg Asp Leu Ala
                 155                 160                 165

 His Phe Pro Ala Val Asp Pro Glu Lys Ile Ala Val Glu Ile Pro
                 170                 175                 180

 Lys Arg Phe Gly Gln Arg Gln Ser Leu Cys His Tyr Thr Leu Lys
                 185                 190                 195

 Asp Asn Lys Val Tyr Ile Lys Thr His Gly Glu His Val Gly Phe
                 200                 205                 210

 Arg Ile Phe Met Asp Ala Ile Leu Leu Ser Leu Thr Arg Lys Val
                 215                 220                 225

 Lys Met Pro Asp Val Glu Leu Phe Val Asn Leu Gly Asp Trp Pro
                 230                 235                 240

 Leu Glu Lys Lys Lys Ser Asn Ser Asn Ile His Pro Ile Phe Ser
                 245                 250                 255

 Trp Cys Gly Ser Thr Asp Ser Lys Asp Ile Val Met Pro Thr Tyr
                 260                 265                 270

 Asp Leu Thr Asp Ser Val Leu Glu Thr Met Gly Arg Val Ser Leu
                 275                 280                 285

 Asp Met Met Ser Val Gln Ala Asn Thr Gly Pro Pro Trp Glu Ser
                 290                 295                 300

 Lys Asn Ser Thr Ala Val Trp Arg Gly Arg Asp Ser Arg Lys Glu
                 305                 310                 315

 Arg Leu Glu Leu Val Lys Leu Ser Arg Lys His Pro Glu Leu Ile
                 320                 325                 330

 Asp Ala Ala Phe Thr Asn Phe Phe Phe Phe Lys His Asp Glu Asn
                 335                 340                 345

 Leu Tyr Gly Pro Ile Val Lys His Ile Ser Phe Phe Asp Phe Phe
                 350                 355                 360

 Lys His Lys Tyr Gln Ile Asn Ile Asp Gly Thr Val Ala Ala Tyr
                 365                 370                 375

 Arg Leu Pro Tyr Leu Leu Val Gly Asp Ser Val Val Leu Lys Gln
                 380                 385                 390

 Asp Ser Ile Tyr Tyr Glu His Phe Tyr Asn Glu Leu Gln Pro Trp
                 395                 400                 405

 Lys His Tyr Ile Pro Val Lys Ser Asn Leu Ser Asp Leu Leu Glu
                 410                 415                 420

 Lys Leu Lys Trp Ala Lys Asp His Asp Glu Glu Ala Lys Lys Ile
                 425                 430                 435

 Ala Lys Ala Gly Gln Glu Phe Ala Arg Asn Asn Leu Met Gly Asp
                 440                 445                 450

 Asp Ile Phe Cys Tyr Tyr Phe Lys Leu Phe Gln Glu Tyr Ala Asn
                 455                 460                 465

 Leu Gln Val Ser Glu Pro Gln Ile Arg Glu Gly Met Lys Arg Val
                 470                 475                 480

 Glu Pro Gln Thr Glu Asp Asp Leu Phe Pro Cys Thr Cys His Arg
                 485                 490                 495

 Lys Lys Thr Lys Asp Glu Leu
                 500

<210> 3419
<211> 3224
<212> DNA
<213> Homo sapien

<400> 3419
 agcggtaaat ttgaaatggc tgacgggtcg ctgacgggcg gcggtctgga 50

 ggcagcggcc atggcgccgg agcgcacggg ctgggcggtg gagcaggagc 100

 tggcgtctct ggagaaaggt ttgttccaag atgaagattc atgcagtgat 150

 tgtagctacc gtgataaacc aggttctagt ttacaaagtt ttatgccaga 200

 aggaaaaacc tttttcccag aaattttcca aacaaatcaa cttttgttct 250

 atgagcgatt cagagcctat caagattaca ttttagctga ctgcaaggcc 300

 tctgaggtac aggaattcac agctgagttc ttggagaagg tccttgagcc 350

 atctggatgg cgggcagtct ggcacactaa tgtgttcaag gtgctggttg 400

 agatcacaga tgtggacttt gcagccttga aggcagtggt gaggcttgct 450

 gaaccatacc tctgtgactc tcaagtgagc acttttacca tggagtgcat 500

 gaaggagctc cttgatctga aggagcatcg gttgcccctg caggagctgt 550

 gggtggtgtt tgatgattca ggagtgtttg accagacagc ccttgcaatt 600

 gagcatgtca gatttttcta ccaaaacatt tggaggagtt gggatgaaga 650

 agaggaggat gaatacgatt attttgtcag atgtgttgaa cctcgattaa 700

 gattgcatta tgacattctt gaagaccgag ttccatcagg acttattgtt 750

 gactaccaca atctgttgtc tcaatgtgag gagagttaca ggaaattttt 800

 aaatctgaga agcagtttgt caaattgtaa ctctgattcc gagcaggaaa 850

 atatctccat ggtggaaggg ttaaaattgt attcggagat ggaacagttg 900

 aaacaaaagc tgaaactcat tgagaatcct ttgttgaggt atgtgtttgg 950

 ttatcagaag aattctaaca tccaagcaaa gggtgtccgt tccagcggtc 1000

 agaagatcac tcatgtggtc tcctccacca tgatggctgg tctcctgcgg 1050

 tccctgctta cggacaggct ttgccaggag cctggtgagg aagaaagaga 1100

 aattcagttc catagtgatc cattgtctgc tataaatgcc tgcttcgaag 1150

 gtgacactgt tattgtttgt cctggccatt atgtggtaca tggcactttc 1200

 tccattgctg actccattga gttggaagga tatggcctac cagatgacat 1250

 tgtgatagaa aagaggggca aaggcgacac ttttgtggac tgcactggtg 1300

 ctgatattaa aatctcaggc ataaaatttg ttcagcatga tgctgtagag 1350

 ggaatcttaa ttgttcaccg tggtaagact acgctggaaa actgtgtgct 1400

 gcagtgtgag acgaccggag tcacagtgcg gacatcagca gagtttctaa 1450

 tgaagaactc ggatttatat ggcgccaagg gtgctggtat agaaatctac 1500

 cctgggagtc agtgcaccct gagtgacaat gggatccatc actgcaagga 1550

 agggatcctc attaaggact tcttagatga acattatgac attcccaaga 1600

 tatccatggt gaataatata atacataata atgaaggtta tggtgttgtc 1650

 ttggtgaaac ctacaatctt ctctgacctg caagaaagtg ctgaagatgg 1700

 aactgaagaa aataaagcgc ttaaaattca gacaagtgga gagccagatg 1750

 tggctgaaag agtggatcta gaagagctga ttgagtgtgc aactggtaaa 1800

 atggagcttt gtgcaagaac tgacccttct gagcaagtcg agggaaattg 1850

 tgaaattgta aatgaactaa ttgctgcctc cacacagaaa ggccagataa 1900

 agaagaaaag gttgagtgaa ctggggatca cgcaagctga tgacaactta 1950

 atgtcacagg agatgtttgt tgggattgtg gggaaccagt tcaagtggaa 2000

 tgggaaaggt agttttggca catttctttt ctgactacag tgatgtaagt 2050

 agatagcaaa atactggatt ttgcacatgc tgccctaaga atcactgctg 2100

 ccattgtagt ttgctgtatt gtctgtattt tatatttgat tatttgggct 2150

 tgagtgaaag gtagatttat ttccatttgc aggtgttgca cataaaacac 2200

 tccctcttta taagaaaaat cataaatgca tataaaatag aaaatatttg 2250

 gagattgctt atctgaaagt cttgctttct tatacacatg gttctctcat 2300

 attaagcctg gtggtaactt tttagtgtaa ttacctttag cacttcaaag 2350

 acgaggaagt aaggaaggga atgcaagact agtgcataaa aatgcaatag 2400

 gtgtcatatg tacagcattc ttcttagagt tgccttttca tcccaattac 2450

 agtgagtctg atttccatcc tgtatttgca taatacttgt cttaaaataa 2500

 aagcttttat gattgggaat ttatctgcct aatcagactt attattgaga 2550

 cgtcaatggg acgcattttt ctgttgagct atgcagtcgt caaaacagcg 2600

 atagacagca taggaggttt gaagcagaaa tgaaatgtgt tattcagagc 2650

 caatgttgta catagagcat tttcactatt gctgaatggg aatgattaaa 2700

 aacaaggtat ttttcgggcc aggcggtggc tcacgcttgt aatcgcagca 2750

 ctttgggagg ctgaggcagg aggatcactt gagcccagga gttcaagact 2800

 agcctaggca acatagtgag accctgtctc tactaaaaat aaatttaaaa 2850

 aaaattagct gagtgtggtg gtgcatgcat gtagttccag ctactcagga 2900

 ggctgaggct agaggatcct tgagcccagg aggttgaggc tgcagtgagg 2950

 tgtgattgcg ccactgcatt ccagcttggg cgacagagcg agacccagtc 3000

 tcaaaaaaaa aaaaagtatt tttctcttac cgttacagta ttctgattat 3050

 attactgaca cagtcaaaat gattaactgt acaacctgta tctgctgggt 3100

 gttcttgtta tcatattgta aaacagcttt aaaaatattt atattttaaa 3150

 aactgtatgt gacattaata tgcctaatga ttaaaattat agtgatgaaa 3200

 taacaaagaa aaaaaaaaaa aaaa 3224

<210> 3420
<211> 672
<212> PRT
<213> Homo sapien

<400> 3420
 Met Ala Asp Gly Ser Leu Thr Gly Gly Gly Leu Glu Ala Ala Ala
   1               5                  10                  15

 Met Ala Pro Glu Arg Thr Gly Trp Ala Val Glu Gln Glu Leu Ala
                  20                  25                  30

 Ser Leu Glu Lys Gly Leu Phe Gln Asp Glu Asp Ser Cys Ser Asp
                  35                  40                  45

 Cys Ser Tyr Arg Asp Lys Pro Gly Ser Ser Leu Gln Ser Phe Met
                  50                  55                  60

 Pro Glu Gly Lys Thr Phe Phe Pro Glu Ile Phe Gln Thr Asn Gln
                  65                  70                  75

 Leu Leu Phe Tyr Glu Arg Phe Arg Ala Tyr Gln Asp Tyr Ile Leu
                  80                  85                  90

 Ala Asp Cys Lys Ala Ser Glu Val Gln Glu Phe Thr Ala Glu Phe
                  95                 100                 105

 Leu Glu Lys Val Leu Glu Pro Ser Gly Trp Arg Ala Val Trp His
                 110                 115                 120

 Thr Asn Val Phe Lys Val Leu Val Glu Ile Thr Asp Val Asp Phe
                 125                 130                 135

 Ala Ala Leu Lys Ala Val Val Arg Leu Ala Glu Pro Tyr Leu Cys
                 140                 145                 150

 Asp Ser Gln Val Ser Thr Phe Thr Met Glu Cys Met Lys Glu Leu
                 155                 160                 165

 Leu Asp Leu Lys Glu His Arg Leu Pro Leu Gln Glu Leu Trp Val
                 170                 175                 180

 Val Phe Asp Asp Ser Gly Val Phe Asp Gln Thr Ala Leu Ala Ile
                 185                 190                 195

 Glu His Val Arg Phe Phe Tyr Gln Asn Ile Trp Arg Ser Trp Asp
                 200                 205                 210

 Glu Glu Glu Glu Asp Glu Tyr Asp Tyr Phe Val Arg Cys Val Glu
                 215                 220                 225

 Pro Arg Leu Arg Leu His Tyr Asp Ile Leu Glu Asp Arg Val Pro
                 230                 235                 240

 Ser Gly Leu Ile Val Asp Tyr His Asn Leu Leu Ser Gln Cys Glu
                 245                 250                 255

 Glu Ser Tyr Arg Lys Phe Leu Asn Leu Arg Ser Ser Leu Ser Asn
                 260                 265                 270

 Cys Asn Ser Asp Ser Glu Gln Glu Asn Ile Ser Met Val Glu Gly
                 275                 280                 285

 Leu Lys Leu Tyr Ser Glu Met Glu Gln Leu Lys Gln Lys Leu Lys
                 290                 295                 300

 Leu Ile Glu Asn Pro Leu Leu Arg Tyr Val Phe Gly Tyr Gln Lys
                 305                 310                 315

 Asn Ser Asn Ile Gln Ala Lys Gly Val Arg Ser Ser Gly Gln Lys
                 320                 325                 330

 Ile Thr His Val Val Ser Ser Thr Met Met Ala Gly Leu Leu Arg
                 335                 340                 345

 Ser Leu Leu Thr Asp Arg Leu Cys Gln Glu Pro Gly Glu Glu Glu
                 350                 355                 360

 Arg Glu Ile Gln Phe His Ser Asp Pro Leu Ser Ala Ile Asn Ala
                 365                 370                 375

 Cys Phe Glu Gly Asp Thr Val Ile Val Cys Pro Gly His Tyr Val
                 380                 385                 390

 Val His Gly Thr Phe Ser Ile Ala Asp Ser Ile Glu Leu Glu Gly
                 395                 400                 405

 Tyr Gly Leu Pro Asp Asp Ile Val Ile Glu Lys Arg Gly Lys Gly
                 410                 415                 420

 Asp Thr Phe Val Asp Cys Thr Gly Ala Asp Ile Lys Ile Ser Gly
                 425                 430                 435

 Ile Lys Phe Val Gln His Asp Ala Val Glu Gly Ile Leu Ile Val
                 440                 445                 450

 His Arg Gly Lys Thr Thr Leu Glu Asn Cys Val Leu Gln Cys Glu
                 455                 460                 465

 Thr Thr Gly Val Thr Val Arg Thr Ser Ala Glu Phe Leu Met Lys
                 470                 475                 480

 Asn Ser Asp Leu Tyr Gly Ala Lys Gly Ala Gly Ile Glu Ile Tyr
                 485                 490                 495

 Pro Gly Ser Gln Cys Thr Leu Ser Asp Asn Gly Ile His His Cys
                 500                 505                 510

 Lys Glu Gly Ile Leu Ile Lys Asp Phe Leu Asp Glu His Tyr Asp
                 515                 520                 525

 Ile Pro Lys Ile Ser Met Val Asn Asn Ile Ile His Asn Asn Glu
                 530                 535                 540

 Gly Tyr Gly Val Val Leu Val Lys Pro Thr Ile Phe Ser Asp Leu
                 545                 550                 555

 Gln Glu Ser Ala Glu Asp Gly Thr Glu Glu Asn Lys Ala Leu Lys
                 560                 565                 570

 Ile Gln Thr Ser Gly Glu Pro Asp Val Ala Glu Arg Val Asp Leu
                 575                 580                 585

 Glu Glu Leu Ile Glu Cys Ala Thr Gly Lys Met Glu Leu Cys Ala
                 590                 595                 600

 Arg Thr Asp Pro Ser Glu Gln Val Glu Gly Asn Cys Glu Ile Val
                 605                 610                 615

 Asn Glu Leu Ile Ala Ala Ser Thr Gln Lys Gly Gln Ile Lys Lys
                 620                 625                 630

 Lys Arg Leu Ser Glu Leu Gly Ile Thr Gln Ala Asp Asp Asn Leu
                 635                 640                 645

 Met Ser Gln Glu Met Phe Val Gly Ile Val Gly Asn Gln Phe Lys
                 650                 655                 660

 Trp Asn Gly Lys Gly Ser Phe Gly Thr Phe Leu Phe
                 665                 670

<210> 3421
<211> 3947
<212> DNA
<213> Homo sapien

<400> 3421
 ttgggaaacc cctacctgtc tgtacctgta ggtcttttct ctggggtctg 50

 gaagaagaat ccttcaatat cttgccttct ggtaatctga gagcagggcg 100

 agaaaaggaa gatcagagtt ccacccttaa atctgtaggt tttcactccc 150

 ccactctcct ttgcagtccc gtggagtctc catctgagcc ctttcctagt 200

 ccaggcatcc cgatgttggt ggatggccca tctgagcggc cagccctgtg 250

 cttcttgctg ttggctgtgg caatgtcttt cttcggctca gctctatcca 300

 tagatgaaac acgggcgcat ctgttgttga aagaaaagat gatgcggctg 350

 ggggggcggc tggtgctgaa taccaaggag gagctggcca atgagaggct 400

 catgacgctc aaaatcgctg agatgaagga ggccatgagg accctgatat 450

 tcccacccag catgcacttt ttccaggcca agcatctcat tgagagaagt 500

 caagtgttta atattctaag gatgatgcca aaaggggctg ccttgcacct 550

 ccatgacatt ggcatcgtga ctatggactg gctggtgagg aatgtcacct 600

 acaggcctca ctgccacatc tgtttcaccc caagggggat catgcagttc 650

 agatttgctc acccaactcc ccgtccatca gaaaaatgtt ccaagtggat 700

 tctgctggag gattatcgga agcgggtgca gaacgtcact gagtttgatg 750

 acagcttgct gaggaatttc actctggtga cccagcaccc ggaggtgatt 800

 tacacaaacc aaaatgttgt ctggtcgaaa tttgaaacca tcttcttcac 850

 catctctggt ctcatccatt acgcaccagt gttcagagac tatgtcttcc 900

 ggagcatgca ggagttctac gaggacaacg tgctctacat ggagatcaga 950

 gccaggctgc tgccggtgta tgagctcagt ggagagcacc atgacgaaga 1000

 gtggtcagtg aagacttacc aggaagtagc tcagaagttt gtggaaactc 1050

 accctgagtt tattggaatc aaaatcattt attcggatca cagatccaaa 1100

 gatgtggctg tcatcgcaga atccatccga atggccatgg ggctccgaat 1150

 caagttcccc acggtggtgg cagggtttga cctggtgggg catgaggaca 1200

 ctggccactc cttgcatgac tacaaggaag ctctgatgat ccccgccaag 1250

 gatggcgtta agctgcctta cttcttccac gccggagaaa cagactggca 1300

 gggtacttcc atagacagga acattctgga tgctctgatg ctgaacacta 1350

 ccagaatcgg ccatggattt gctttgagca aacaccccgc agtcaggact 1400

 tactcctgga aaaaggacat ccccatagaa gtctgtccca tctctaacca 1450

 ggtgctgaaa ctggtgtctg acttgaggaa ccaccctgta gccactctga 1500

 tggccactgg gcaccccatg gtgatcagct ctgatgaccc agctatgttt 1550

 ggtgccaaag gcttgtccta tgatttctat gaggtcttca tgggcattgg 1600

 ggggatgaag gctgacctga ggaccctcaa acagctggcc atgaactcta 1650

 tcaagtacag taccctgttg gagagtgaga aaaatacttt catggaaatc 1700

 tggaagaaga gatgggataa gttcatagca gatgtggcta caaagtgagg 1750

 agaagctagc cagccctcta caagctgtct tcttgcacac gctgtcactt 1800

 cctctcactc gttcttgaat cagctccatg tgcccatgaa atcaatggcc 1850

 tctgtatgga gcgaccctgt gagaagcact tggctggctg agcaaattca 1900

 tcctctggaa atattctctc tcagccacag tgacattgac cctcttggtt 1950

 ttctcctgtc tctggccatt tcttccagtt tccctatttc agagtcttct 2000

 cctctctctg atctctgtgc tgtttcctca ggactcagtc ctgggctctc 2050

 ttctattctg gtctctttat ttttttattt ttgtattttt tcgagatgga 2100

 gttttgctct tgttgcccag gctggagtac aatggtgcga tctcagctca 2150

 gtgcaacctc cgccacccgg gttcaggcaa ttctcttgca tcagcctcgc 2200

 gagtagttgg aattataggc atgtgccacc acacccagct gatttttgca 2250

 tttttagtag agacaggttt tcaccatgtt ggcgaggctg gtatccaact 2300

 cttgacctca ggtgatccac tcgccccttg gctcccaaag tgctggaatt 2350

 acaggcatta gccaccatgc ctggcctatt ctggtctctt taactctctc 2400

 ctctttattt ctcttctctc tctgtacact tttcctgggt ggtctcatcc 2450

 attcctttgc tttttcatac catttatttg ttaatgattc ccacatttat 2500

 ttatgcactt ggagagctca caggaatctc agaaactgat gaggtacaat 2550

 tctgaaccct cagtctcttc cctttaaacc tttctttttc tctactttaa 2600

 tttttctaaa gagtgtcttg ctatgttgcc caggctggtc tccaactcaa 2650

 gtgatcctcc tgccgcagtc tcccgaagtg ctgggattac tgacatgagc 2700

 caccacactc agccctttaa acctttccct ggcctttccc atagctggtg 2750

 aaggacacct ccatccattc cacgcagttg ctcaaagcag aaattttcag 2800

 tgcaagtctt gatgctgcgc cgtcccccac tccctacatc agaacgcatc 2850

 cctcatctgg actccagcgg tggcttcttg atgctgcgcg gtcccccact 2900

 ccctacatca gaatgcatcc cgcatccaga ctccagcggt ggtgctctac 2950

 ctgcacgctg ttgccaagtc caagctacca tactcctgcc tgagctatga 3000

 caacagcctc ctcactgatc tcccctttct tccctttgcc tcctccagct 3050

 catttttcac agtgtagaat gacattttgt ttgtttgttt tgttttgttt 3100

 gagatggagt ctcgctctgt tgcccagggt ggagtgcagc ggtgcgatct 3150

 cggctcactg caacctccac ctcccgggtt caagcggatt ctcgtgcctc 3200

 agcctcctga gtagctggga ttacaggcat gcaccaccat gcccggataa 3250

 tttttgtatt tttagtagag atggggtttc actatgttgg ccaggctggt 3300

 ctcgaacacc tgacctcgtg gtccacccgc ctcggcctcc caaagcactg 3350

 ggattacagg cgtgagccac ccggcctggc ctagaatgac ttttaaaaga 3400

 tcaaattaaa tcaggtcact cctttgctta caacgcagtg cgtttagagg 3450

 tacaccccat gtctccacag ggcatacagc atccgattta atctggatcc 3500

 attccggcgc cttcctctcc cagtcaccca gagggcccca accccggcgg 3550

 ccctttcttc ctcaaatgtc ctcggctcta taccgtgcct gggtcttttc 3600

 tctttctctc tgcctggaag attccttctt tccccttttg tcttgcccac 3650

 tcctgtttac ccttcaagtt tcaagttcat gtcactgtct cagagaggtt 3700

 ttcctgtgct cgccctgttt ctctcaggaa gccttgctct tttccatcat 3750

 gcctctaatc acagcttata atcggatatt tatttctgtg tctacagtct 3800

 tgccctgcca gactgtatgc cccatgtggg caggcgctca tgattgtttc 3850

 tgattgtttc acgcatgctg ctaacccaga gcctgggccc aaagctagtt 3900

 agtactcaat aaacaatgca ttgaatgcat tgaaaaaaaa aaaaaaa 3947

<210> 3422
<211> 511
<212> PRT
<213> Homo sapien

<400> 3422
 Met Leu Val Asp Gly Pro Ser Glu Arg Pro Ala Leu Cys Phe Leu
   1               5                  10                  15

 Leu Leu Ala Val Ala Met Ser Phe Phe Gly Ser Ala Leu Ser Ile
                  20                  25                  30

 Asp Glu Thr Arg Ala His Leu Leu Leu Lys Glu Lys Met Met Arg
                  35                  40                  45

 Leu Gly Gly Arg Leu Val Leu Asn Thr Lys Glu Glu Leu Ala Asn
                  50                  55                  60

 Glu Arg Leu Met Thr Leu Lys Ile Ala Glu Met Lys Glu Ala Met
                  65                  70                  75

 Arg Thr Leu Ile Phe Pro Pro Ser Met His Phe Phe Gln Ala Lys
                  80                  85                  90

 His Leu Ile Glu Arg Ser Gln Val Phe Asn Ile Leu Arg Met Met
                  95                 100                 105

 Pro Lys Gly Ala Ala Leu His Leu His Asp Ile Gly Ile Val Thr
                 110                 115                 120

 Met Asp Trp Leu Val Arg Asn Val Thr Tyr Arg Pro His Cys His
                 125                 130                 135

 Ile Cys Phe Thr Pro Arg Gly Ile Met Gln Phe Arg Phe Ala His
                 140                 145                 150

 Pro Thr Pro Arg Pro Ser Glu Lys Cys Ser Lys Trp Ile Leu Leu
                 155                 160                 165

 Glu Asp Tyr Arg Lys Arg Val Gln Asn Val Thr Glu Phe Asp Asp
                 170                 175                 180

 Ser Leu Leu Arg Asn Phe Thr Leu Val Thr Gln His Pro Glu Val
                 185                 190                 195

 Ile Tyr Thr Asn Gln Asn Val Val Trp Ser Lys Phe Glu Thr Ile
                 200                 205                 210

 Phe Phe Thr Ile Ser Gly Leu Ile His Tyr Ala Pro Val Phe Arg
                 215                 220                 225

 Asp Tyr Val Phe Arg Ser Met Gln Glu Phe Tyr Glu Asp Asn Val
                 230                 235                 240

 Leu Tyr Met Glu Ile Arg Ala Arg Leu Leu Pro Val Tyr Glu Leu
                 245                 250                 255

 Ser Gly Glu His His Asp Glu Glu Trp Ser Val Lys Thr Tyr Gln
                 260                 265                 270

 Glu Val Ala Gln Lys Phe Val Glu Thr His Pro Glu Phe Ile Gly
                 275                 280                 285

 Ile Lys Ile Ile Tyr Ser Asp His Arg Ser Lys Asp Val Ala Val
                 290                 295                 300

 Ile Ala Glu Ser Ile Arg Met Ala Met Gly Leu Arg Ile Lys Phe
                 305                 310                 315

 Pro Thr Val Val Ala Gly Phe Asp Leu Val Gly His Glu Asp Thr
                 320                 325                 330

 Gly His Ser Leu His Asp Tyr Lys Glu Ala Leu Met Ile Pro Ala
                 335                 340                 345

 Lys Asp Gly Val Lys Leu Pro Tyr Phe Phe His Ala Gly Glu Thr
                 350                 355                 360

 Asp Trp Gln Gly Thr Ser Ile Asp Arg Asn Ile Leu Asp Ala Leu
                 365                 370                 375

 Met Leu Asn Thr Thr Arg Ile Gly His Gly Phe Ala Leu Ser Lys
                 380                 385                 390

 His Pro Ala Val Arg Thr Tyr Ser Trp Lys Lys Asp Ile Pro Ile
                 395                 400                 405

 Glu Val Cys Pro Ile Ser Asn Gln Val Leu Lys Leu Val Ser Asp
                 410                 415                 420

 Leu Arg Asn His Pro Val Ala Thr Leu Met Ala Thr Gly His Pro
                 425                 430                 435

 Met Val Ile Ser Ser Asp Asp Pro Ala Met Phe Gly Ala Lys Gly
                 440                 445                 450

 Leu Ser Tyr Asp Phe Tyr Glu Val Phe Met Gly Ile Gly Gly Met
                 455                 460                 465

 Lys Ala Asp Leu Arg Thr Leu Lys Gln Leu Ala Met Asn Ser Ile
                 470                 475                 480

 Lys Tyr Ser Thr Leu Leu Glu Ser Glu Lys Asn Thr Phe Met Glu
                 485                 490                 495

 Ile Trp Lys Lys Arg Trp Asp Lys Phe Ile Ala Asp Val Ala Thr
                 500                 505                 510

 Lys


<210> 3423
<211> 7603
<212> DNA
<213> Homo sapien

<400> 3423
 ttttcttgct tttcttccct tttttttctt tttgcaaaca aaacaaaaaa 50

 cagcatagaa gaaagagcaa aataaagaag aagaagagga ggaagagagg 100

 gaaagagagg aagggaaaaa aaacaccaac ccgggcagag gaggaggtgc 150

 ggcggcggcg gcggcggcgg cagcggcggc agcggcgcgg cggcggctcg 200

 gaccccctcc cccggctccc cccatcagtg cagctctccg ggcgatgcca 250

 gaatagatgc cggggcaatg tcccgccgca aacagggcaa cccgcagcac 300

 ttgtcccaga gggagctcat caccccagag gctgaccatg tggaggccgc 350

 catcctcgaa gaagacgagg gtctggagat agaggagcca agtggcctgg 400

 ggctgatggt gggtggcccc gaccctgacc tgctcacctg tggccagtgt 450

 caaatgaact tccccttggg ggacatcctg gtttttatag agcacaaaag 500

 gaagcagtgt ggcggcagct tgggtgcctg ctatgacaag gccctggaca 550

 aggacagccc gccaccctcc tcacgctccg agctcaggaa agtgtccgag 600

 ccggtggaga tcgggatcca agtcaccccc gacgaagatg accacctgct 650

 ctcacccacg aaaggcatct gtcccaagca ggagaacatt gcaggtaaag 700

 atgagccttc cagctacatt tgcacaacat gcaagcagcc cttcaacagc 750

 gcgtggttcc tgctgcagca cgcgcagaac acgcacggct tccgcatcta 800

 cctggagccc gggccggcca gcagctcgct cacgccgcgg ctcaccatcc 850

 cgccgccgct cgggccggag gccgtggcgc agtccccgct catgaatttc 900

 ctgggcgaca gcaacccctt caacctgctg cgcatgacgg gccccatcct 950

 gcgggaccac ccgggcttcg gcgagggccg cctgccgggc acgccgcctc 1000

 tcttcagtcc cccgccgcgc caccacctgg acccgcaccg cctcagtgcc 1050

 gaggagatgg ggctcgtcgc ccagcacccc agtgccttcg accgagtcat 1100

 gcgcctgaac cccatggcca tcgactcgcc cgccatggac ttctcgcggc 1150

 ggctccgcga gctggcgggc aacagctcca cgccgccgcc cgtgtccccg 1200

 ggccgcggca accctatgca ccggctcctg aaccccttcc agcccagccc 1250

 caagtccccg ttcctgagca cgccgccgct gccgcccatg ccccctggcg 1300

 gcacgccgcc cccgcagccg ccagccaaga gcaagtcgtg cgagttctgc 1350

 ggcaagacct tcaagttcca gagcaatctc atcgtgcacc ggcgcagtca 1400

 cacgggcgag aagccctaca agtgccagct gtgcgaccac gcgtgctcgc 1450

 aggccagcaa gctcaagcgc cacatgaaga cgcacatgca caaggccggc 1500

 tcgctggccg gccgctccga cgacgggctc tcggccgcca gctcccccga 1550

 gcccggcacc agcgagctgg cgggcgaggg cctcaaggcg gccgacggtg 1600

 acttccgcca ccacgagagc gacccgtcgc tgggccacga gccggaggag 1650

 gaggacgagg aggaggagga ggaggaggag gagctgctac tggagaacga 1700

 gagccggccc gagtcgagct tcagcatgga ctcggagctg agccgcaacc 1750

 gcgagaacgg cggtggtggg gtgcccgggg tcccgggcgc ggggggcggc 1800

 gcggccaagg cgctggctga cgagaaggcg ctggtgctgg gcaaggtcat 1850

 ggagaacgtg ggcctaggcg cactgccgca gtacggcgag ctcctggccg 1900

 acaagcagaa gcgcggcgcc ttcctgaagc gtgcggcggg cggcggggac 1950

 gcgggcgacg acgacgacgc gggcggctgc ggggacgcgg gcgcgggcgg 2000

 cgcggtcaac gggcgcgggg gcggcttcgc gccaggcacc gagcccttcc 2050

 ccgggctctt cccgcgcaag cccgcgccgc tgcccagccc cgggctcaac 2100

 agcgccgcca agcgcatcaa ggtggagaag gacctggagc tgccgcccgc 2150

 cgcgctcatc ccgtccgaga acgtgtactc gcagtggctg gtgggctacg 2200

 cggcgtcgcg gcacttcatg aaggacccct tcctgggctt cacggacgca 2250

 cgacagtcgc ccttcgccac gtcgtccgag cactcgtccg agaacggcag 2300

 cctgcgcttc tccacgccgc ccggggacct gctggacggc ggcctctcgg 2350

 gccgcagcgg cacggccagc ggaggcagca ccccgcacct gggcggcccg 2400

 ggccccgggc ggcccagctc caaggagggc cgccgcagcg acacgtgcga 2450

 gtactgcggc aaggtgttca agaactgcag caacttgacg gtgcaccggc 2500

 ggagccacac cggcgagcgg ccttacaagt gcgagctgtg caactacgcg 2550

 tgcgcgcaga gcagcaagct cacgcgccac atgaagacgc acgggcagat 2600

 cggcaaggag gtgtaccgct gcgacatctg ccagatgccc ttcagcgtct 2650

 acagcaccct ggagaaacac atgaaaaagt ggcacggcga gcacttgctg 2700

 actaacgacg tcaaaatcga gcaggccgag aggagctaag cgcgcgggcc 2750

 ccggcgcccc gcacctgtac agtggaaccg ttgccaaccg agagaatgct 2800

 gacctgactt gcctccgtgt caccgccacc ccgcaccccg cgtgtccccg 2850

 gggcccaggg gaggcggcac tccaacctaa cctgtgtctg cgaagtccta 2900

 tggaaacccg agggttgatt aaggcagtac aaattgtgga gccttttaac 2950

 tgtgcaataa tttctgtatt tattgggttt tgtaattttt ttggcatgtg 3000

 caggtacttt ttattattat tttttctgtt tgaattcctt taagagattt 3050

 tgttgggtat ccatcccttc tttgtttttt ttttaacccg gtagtagcct 3100

 gagcaatgac tcgcaagcaa tgttagaggg gaagcatatc ttttaaatta 3150

 taatttgggg ggaggggtgg tgctgctttt ttgaaattta agctaagcat 3200

 gtgtaatttc ttgtgaagaa gccaacactc aaatgacttt taaagttgtt 3250

 tactttttca ttccttcctt ttttttgtcc tgaaataaaa agtggcatgc 3300

 agtttttttt ttaattattt tttaattttt tttttggttt ttgtttttgg 3350

 ggtggggggt gtggatgtac agcggataac aatctttcaa gtcgtagcac 3400

 tttgtttcag aactggaatg gagatgtagc actcatgtcg tcccgagtca 3450

 agcggccttt tctgtgttga tttcggcttt catattacat aagggaaacc 3500

 ttgagtggtg gtgctggggg aggcacccca cagactcagc gccgccagag 3550

 atagggtttt tggagggctc ctctgggaaa tggcccgaca gcattctgag 3600

 gttgtgcatg accagcagat actatcctgt tggtgtgccc tggggtgcca 3650

 tggctgctat tcgctgtaga ttaggctaca taaaatgggc tgagggtacc 3700

 tttttgggga gatggggtgg cctgcagtga cacagaaagg aagaaactag 3750

 cggtgttctt ttaggcgttt tctggcttga cggcttctct ctttttttaa 3800

 atcaccccca ccacataaat ctcaaatcct atgttgctac aaggggtcat 3850

 ccatcatttc ccaagcagac gaatgcccta attaattgaa gttagtgttc 3900

 tctcatttaa tgcacactga tgatattgta gggatgggtg gggtggggat 3950

 cttgcaaatt tctattctct tttactgaaa aagcagggga tgagttccat 4000

 cagaaggtgc ccagcgctac ttcccaggtt tttatttttt ttttcctatc 4050

 tcattaggtt ggaaggtact aaatattgaa ctgttaagat tagacatttg 4100

 aattctgttg acccgcactt taaagctttt gtttgcattt aaattaaatg 4150

 gcttctaaac aagaaattgc agcatattct tctctttggc ccagaggtgg 4200

 gttaaactgt aagggacagc tgagattgag tgtcagtatt gctaagcgtg 4250

 gcattcacaa tactggcact ataaagaaca aaataaaata ataatttata 4300

 ggacagtttt tctactgcca ttcaatttga tgtgagtgcc ttgaaaactg 4350

 atcttcctat ttgagtctct tgagacaaat gcaaaacttt ttttttgaaa 4400

 tgaaaagact ttttaaaaaa gtaaaacaag aaaagtacat tctttagaaa 4450

 ctaacaaagc cacatttact ttaagtaaaa aaaaaaaaaa ttctggttga 4500

 agatagagga tatgaaatgc cataagaccc aatcaaatga agaaataaac 4550

 ccagcacaac cttggacatc cattagctga attatcctca gccccttttg 4600

 tttttgggac aacgctgctt agatatggag tggaggtgat ttactgctga 4650

 attaaaactc aagtgacaca agttacaagt tgatatcgtt gaatgaaaag 4700

 caaaacaaaa acaattcagg aacaacggct aattttttct aaagttaaat 4750

 ttagtgcact ctgtcttaaa aatacgttta cagtattggg tacatacaag 4800

 ggtaaaaaaa aaattgtgtg tatgtgtgtt ggagcgatct ttttttttca 4850

 aagtttgctt aataggttat acaaaaatgc cacagtggcc gcgtgtatat 4900

 tgttttcttt tggtgacggg gttttagtat atattatata tattaaaatt 4950

 tcttgattac tgtaaaagtg gaccagtatt tgtaataatc gagaatgcct 5000

 gggcatttta caaaacaaga aaaaaaatac ccttttcttt tccttgaaaa 5050

 tgttgcagta aaatttaaat ggtgggtcta taaatttgtt cttgttacag 5100

 taactgtaaa gtcggagttt tagtaaattt ttttctgcct tgggtgttga 5150

 atttttattt caaaaaaaat gtatagaaac ttgtatttgg ggattcaaag 5200

 gggattgcta caccatgtag aaaaagtatg tagaaaaaaa gtgcttaata 5250

 ttgttattgc tttgcagaaa aaaaaaaaat cacatttctg acctgtactt 5300

 atttttctct tcccgcctcc ctctggaatg gatatattgg ttggttcata 5350

 tgatgtaggc acttgctgta tttttactgg agctcgtaat tttttaactg 5400

 taagcttgtc cttttaaagg gatttaatgt acctttttgt tagtgaattt 5450

 ggaaataaaa agaaaaaaaa aacaaaaaca aacaggctgc cataatatat 5500

 ttttttaatt tggcaggata aaatattgca aaaaaaacac atttgtatgt 5550

 taagtcctat tgtacaggag aaaaagggtt gtttgacaac ctttgagaaa 5600

 aagaaacaaa aggaagtagt taaatgcttt ggttcacaaa tcatttagtt 5650

 gtatatattt tttgtcggaa ttggcctaca cagagaaccg ttcgtgttgg 5700

 gcttctctct gaacgccccg aaccttgcat caaggctcct tggtgtggcc 5750

 acagcagacc agatgggaaa ttatttgtgt tgagtggaaa aaaatcagtt 5800

 tttgtaaaga tgtcagtaac attccacatc gtcctccctt tctctaagag 5850

 gccatctcta agatgtcaga tgtagaggag agagagcgag agaacatctt 5900

 ccttctctac catcactcct gtggcggtca ccaccaccac ctctcccgcc 5950

 cttaccagca gaaagcaatg caaactgagc tgctttagtc cttgagaaat 6000

 tgtgaaacaa acacaaatat cataaaagga gctggtgatt cagctgggtc 6050

 caggtgaagt gacctgctgt tgagaccggt acaaattgga tttcaggaag 6100

 gagactccat cacagccagg acctttcgtg ccatggagag tgttggcctc 6150

 ttgtctttct tccctgcttt gctgctttgc tctctgaaac ctacattccg 6200

 tcagtttccg aatgcgaggg cctgggatga atttggtgcc tttccatatc 6250

 tcgttctctc tccttcccct gcgtttcctc tccatccttc atcctccatt 6300

 ggtccttttt ttttctttca ttttttattt aatttctttt cttcctgtct 6350

 gttcctcccc taatcctcta ttttattttt attttttgta aagccaagta 6400

 gctttaagat aaagtggtgg tcttttggat gagggaataa tgcattttta 6450

 aataaaatac caatatcagg aagccatttt ttatttcagg aaatgtaaga 6500

 aaccattatt tcaggttatg aaagtataac caagcatcct tttgggcaat 6550

 tccttaccaa atgcagaagc ttttctgttc gatgcactct ttcctccttg 6600

 ccacttacct ttgcaaagtt aaaaaaaagg ggggagggaa tgggagagaa 6650

 agctgagatt tcagtttcct actgcagttt cctacctgca gatccagggg 6700

 ctgctgttgc ctttggatgc cccactgagg tcctagagtg cctccagggt 6750

 ggtcttcctg tagtcataac agctagccag tgctcaccag cttaccagat 6800

 tgccaggact aagccatccc aaagcacaag cattgtgtgt ctctgtgact 6850

 gcagagaaga gagaattttg cttctgtttt gtgtttaaaa aaccaacacg 6900

 gaagcagatg atcccgagag agaggcctct agcatgggtg acccagccga 6950

 cctcaggccg gtttccgcac tgccacaact ttgttcaaag ttgcccccaa 7000

 ttggaacctg ccacttggca ttagagggtc tttcatgggg agagaaggag 7050

 actgaattac tctaagcaaa atgtgaaaag taaggaaatc agcctttcat 7100

 cccggtccta agtaaccgtc agccgaaggt ctcgtggaac acaggcaaac 7150

 ccgtgatttt ggtgctcctt gtaactcagc cctgcaaagc aaagtcccat 7200

 tgatttaagt tgtttgcatt tgtactggca aggcaaaata tttttattac 7250

 cttttctatt acttattgta tgagcttttg ttgtttactt ggaggttttg 7300

 tcttttacta caagtttgga actatttatt attgcttggt atttgtgctc 7350

 tgtttaagaa acaggcactt ttttttatta tggataaaat gttgagatga 7400

 caggaggtca tttcaatatg gcttagtaaa atatttattg ttcctttatt 7450

 ctctgtacaa gattttgggc ctcttttttt ccttaatgtc acaatgttga 7500

 gttcagcatg tgtctgccat ttcatttgta cgcttgttca aaaccaagtt 7550

 tgttctggtt tcaagttata aaaataaatt ggacatttaa cttgatctcc 7600

 aaa 7603

<210> 3424
<211> 823
<212> PRT
<213> Homo sapien

<400> 3424
 Met Ser Arg Arg Lys Gln Gly Asn Pro Gln His Leu Ser Gln Arg
   1               5                  10                  15

 Glu Leu Ile Thr Pro Glu Ala Asp His Val Glu Ala Ala Ile Leu
                  20                  25                  30

 Glu Glu Asp Glu Gly Leu Glu Ile Glu Glu Pro Ser Gly Leu Gly
                  35                  40                  45

 Leu Met Val Gly Gly Pro Asp Pro Asp Leu Leu Thr Cys Gly Gln
                  50                  55                  60

 Cys Gln Met Asn Phe Pro Leu Gly Asp Ile Leu Val Phe Ile Glu
                  65                  70                  75

 His Lys Arg Lys Gln Cys Gly Gly Ser Leu Gly Ala Cys Tyr Asp
                  80                  85                  90

 Lys Ala Leu Asp Lys Asp Ser Pro Pro Pro Ser Ser Arg Ser Glu
                  95                 100                 105

 Leu Arg Lys Val Ser Glu Pro Val Glu Ile Gly Ile Gln Val Thr
                 110                 115                 120

 Pro Asp Glu Asp Asp His Leu Leu Ser Pro Thr Lys Gly Ile Cys
                 125                 130                 135

 Pro Lys Gln Glu Asn Ile Ala Gly Lys Asp Glu Pro Ser Ser Tyr
                 140                 145                 150

 Ile Cys Thr Thr Cys Lys Gln Pro Phe Asn Ser Ala Trp Phe Leu
                 155                 160                 165

 Leu Gln His Ala Gln Asn Thr His Gly Phe Arg Ile Tyr Leu Glu
                 170                 175                 180

 Pro Gly Pro Ala Ser Ser Ser Leu Thr Pro Arg Leu Thr Ile Pro
                 185                 190                 195

 Pro Pro Leu Gly Pro Glu Ala Val Ala Gln Ser Pro Leu Met Asn
                 200                 205                 210

 Phe Leu Gly Asp Ser Asn Pro Phe Asn Leu Leu Arg Met Thr Gly
                 215                 220                 225

 Pro Ile Leu Arg Asp His Pro Gly Phe Gly Glu Gly Arg Leu Pro
                 230                 235                 240

 Gly Thr Pro Pro Leu Phe Ser Pro Pro Pro Arg His His Leu Asp
                 245                 250                 255

 Pro His Arg Leu Ser Ala Glu Glu Met Gly Leu Val Ala Gln His
                 260                 265                 270

 Pro Ser Ala Phe Asp Arg Val Met Arg Leu Asn Pro Met Ala Ile
                 275                 280                 285

 Asp Ser Pro Ala Met Asp Phe Ser Arg Arg Leu Arg Glu Leu Ala
                 290                 295                 300

 Gly Asn Ser Ser Thr Pro Pro Pro Val Ser Pro Gly Arg Gly Asn
                 305                 310                 315

 Pro Met His Arg Leu Leu Asn Pro Phe Gln Pro Ser Pro Lys Ser
                 320                 325                 330

 Pro Phe Leu Ser Thr Pro Pro Leu Pro Pro Met Pro Pro Gly Gly
                 335                 340                 345

 Thr Pro Pro Pro Gln Pro Pro Ala Lys Ser Lys Ser Cys Glu Phe
                 350                 355                 360

 Cys Gly Lys Thr Phe Lys Phe Gln Ser Asn Leu Ile Val His Arg
                 365                 370                 375

 Arg Ser His Thr Gly Glu Lys Pro Tyr Lys Cys Gln Leu Cys Asp
                 380                 385                 390

 His Ala Cys Ser Gln Ala Ser Lys Leu Lys Arg His Met Lys Thr
                 395                 400                 405

 His Met His Lys Ala Gly Ser Leu Ala Gly Arg Ser Asp Asp Gly
                 410                 415                 420

 Leu Ser Ala Ala Ser Ser Pro Glu Pro Gly Thr Ser Glu Leu Ala
                 425                 430                 435

 Gly Glu Gly Leu Lys Ala Ala Asp Gly Asp Phe Arg His His Glu
                 440                 445                 450

 Ser Asp Pro Ser Leu Gly His Glu Pro Glu Glu Glu Asp Glu Glu
                 455                 460                 465

 Glu Glu Glu Glu Glu Glu Glu Leu Leu Leu Glu Asn Glu Ser Arg
                 470                 475                 480

 Pro Glu Ser Ser Phe Ser Met Asp Ser Glu Leu Ser Arg Asn Arg
                 485                 490                 495

 Glu Asn Gly Gly Gly Gly Val Pro Gly Val Pro Gly Ala Gly Gly
                 500                 505                 510

 Gly Ala Ala Lys Ala Leu Ala Asp Glu Lys Ala Leu Val Leu Gly
                 515                 520                 525

 Lys Val Met Glu Asn Val Gly Leu Gly Ala Leu Pro Gln Tyr Gly
                 530                 535                 540

 Glu Leu Leu Ala Asp Lys Gln Lys Arg Gly Ala Phe Leu Lys Arg
                 545                 550                 555

 Ala Ala Gly Gly Gly Asp Ala Gly Asp Asp Asp Asp Ala Gly Gly
                 560                 565                 570

 Cys Gly Asp Ala Gly Ala Gly Gly Ala Val Asn Gly Arg Gly Gly
                 575                 580                 585

 Gly Phe Ala Pro Gly Thr Glu Pro Phe Pro Gly Leu Phe Pro Arg
                 590                 595                 600

 Lys Pro Ala Pro Leu Pro Ser Pro Gly Leu Asn Ser Ala Ala Lys
                 605                 610                 615

 Arg Ile Lys Val Glu Lys Asp Leu Glu Leu Pro Pro Ala Ala Leu
                 620                 625                 630

 Ile Pro Ser Glu Asn Val Tyr Ser Gln Trp Leu Val Gly Tyr Ala
                 635                 640                 645

 Ala Ser Arg His Phe Met Lys Asp Pro Phe Leu Gly Phe Thr Asp
                 650                 655                 660

 Ala Arg Gln Ser Pro Phe Ala Thr Ser Ser Glu His Ser Ser Glu
                 665                 670                 675

 Asn Gly Ser Leu Arg Phe Ser Thr Pro Pro Gly Asp Leu Leu Asp
                 680                 685                 690

 Gly Gly Leu Ser Gly Arg Ser Gly Thr Ala Ser Gly Gly Ser Thr
                 695                 700                 705

 Pro His Leu Gly Gly Pro Gly Pro Gly Arg Pro Ser Ser Lys Glu
                 710                 715                 720

 Gly Arg Arg Ser Asp Thr Cys Glu Tyr Cys Gly Lys Val Phe Lys
                 725                 730                 735

 Asn Cys Ser Asn Leu Thr Val His Arg Arg Ser His Thr Gly Glu
                 740                 745                 750

 Arg Pro Tyr Lys Cys Glu Leu Cys Asn Tyr Ala Cys Ala Gln Ser
                 755                 760                 765

 Ser Lys Leu Thr Arg His Met Lys Thr His Gly Gln Ile Gly Lys
                 770                 775                 780

 Glu Val Tyr Arg Cys Asp Ile Cys Gln Met Pro Phe Ser Val Tyr
                 785                 790                 795

 Ser Thr Leu Glu Lys His Met Lys Lys Trp His Gly Glu His Leu
                 800                 805                 810

 Leu Thr Asn Asp Val Lys Ile Glu Gln Ala Glu Arg Ser
                 815                 820

<210> 3425
<211> 792
<212> DNA
<213> Homo sapien

<400> 3425
 ccaagctcca gctgtttgtc aaggcgagtg aggacgggga gagcgtgggt 50

 cactgcccct cctgccagcg gtcttcatgg tcctgctcct caagggcgta 100

 cctttcaccc tcaccacggt ggacacgcgc aggtccccgg acgtgctgaa 150

 ggacttcgcc cccggctcgc agctgcccat cctgctctat gacagcgacg 200

 ccaagacaga cacgctgcag atcgaggact ttctggagga gacgctgggg 250

 ccgcccgact tccccagcct ggcgcctcgt tacagggagt ccaacaccgc 300

 cggcaacgac gttttccaca agttctccgc gttcatcaag aacccggtgc 350

 ccgcgcagga cgaagccctg taccagcagc tgctgcgcgc cctcgccagg 400

 ctggacagct acctgcgcgc gcccctggag cacgagctgg cgggggagcc 450

 gcagctgcgc gagtcccgcc gccgcttcct ggacggcgac aggctcacgc 500

 tggccgactg cagcctcctg cccaagctgc acatcgtcga cacggtgtgc 550

 gcgcacttcc gccaggcgcc catccccgcg gagctgcgcg gcgtacgccg 600

 ctacctggac agcgcgatgc aggagaaaga gttcaaatac acgtgtccgc 650

 acagcgccga gatcctggcg gcctaccggc ccgccgtgca cccccgctag 700

 cgccccaccc cgcgtctgtc gcccaataaa ggcatctttg tcgggaaaaa 750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 792

<210> 3426
<211> 207
<212> PRT
<213> Homo sapien

<400> 3426
 Met Val Leu Leu Leu Lys Gly Val Pro Phe Thr Leu Thr Thr Val
   1               5                  10                  15

 Asp Thr Arg Arg Ser Pro Asp Val Leu Lys Asp Phe Ala Pro Gly
                  20                  25                  30

 Ser Gln Leu Pro Ile Leu Leu Tyr Asp Ser Asp Ala Lys Thr Asp
                  35                  40                  45

 Thr Leu Gln Ile Glu Asp Phe Leu Glu Glu Thr Leu Gly Pro Pro
                  50                  55                  60

 Asp Phe Pro Ser Leu Ala Pro Arg Tyr Arg Glu Ser Asn Thr Ala
                  65                  70                  75

 Gly Asn Asp Val Phe His Lys Phe Ser Ala Phe Ile Lys Asn Pro
                  80                  85                  90

 Val Pro Ala Gln Asp Glu Ala Leu Tyr Gln Gln Leu Leu Arg Ala
                  95                 100                 105

 Leu Ala Arg Leu Asp Ser Tyr Leu Arg Ala Pro Leu Glu His Glu
                 110                 115                 120

 Leu Ala Gly Glu Pro Gln Leu Arg Glu Ser Arg Arg Arg Phe Leu
                 125                 130                 135

 Asp Gly Asp Arg Leu Thr Leu Ala Asp Cys Ser Leu Leu Pro Lys
                 140                 145                 150

 Leu His Ile Val Asp Thr Val Cys Ala His Phe Arg Gln Ala Pro
                 155                 160                 165

 Ile Pro Ala Glu Leu Arg Gly Val Arg Arg Tyr Leu Asp Ser Ala
                 170                 175                 180

 Met Gln Glu Lys Glu Phe Lys Tyr Thr Cys Pro His Ser Ala Glu
                 185                 190                 195

 Ile Leu Ala Ala Tyr Arg Pro Ala Val His Pro Arg
                 200                 205

<210> 3427
<211> 2992
<212> DNA
<213> Homo sapien

<400> 3427
 ctcgtctttc tcccgggaac cttgacgacg ccttccgctt ggccctgcct 50

 tctgccgcat ccccgccgcc gcggcgcctt gaggagcagg agaagacgca 100

 gccgggccgc cgccgttaga ggggttcccg gccgccgctc gccccgtcgg 150

 ccgccaccgc ctccggggtc agccctctct ctgggtctcc gctttctcct 200

 gccgccagcg cccgctcatc gccgcgatgg ggctcctgga ctcggagccg 250

 ggtagtgtcc taaacgtagt gtccacggca ctcaacgaca cggtagagtt 300

 ctaccgctgg acctggtcca tcgcagataa gcgtgtggaa aattggcctc 350

 tgatgcagtc tccttggcct acactaagta taagcactct ttatctcctg 400

 tttgtgtggc tgggtccaaa atggatgaag gaccgagaac cttttcagat 450

 gcgtctagtg ctcattatct ataattttgg gatggttttg cttaacctct 500

 ttatcttcag agagttattc atgggatcat ataatgcggg atatagctat 550

 atttgccaga gtgtggatta ttctaataat gttcatgaag tcaggatagc 600

 tgctgctctg tggtggtact ttgtatctaa aggagttgag tatttggaca 650

 cagtgttttt tattctgaga aagaaaaaca accaagtttc tttccttcat 700

 gtgtatcatc actgtacgat gtttaccttg tggtggattg gaattaagtg 750

 ggttgcagga ggacaagcat tttttggagc ccagttgaat tcctttatcc 800

 atgtgattat gtactcatac tatgggttaa ctgcatttgg cccatggatt 850

 cagaaatatc tttggtggaa acgatacctg actatgttgc aactgattca 900

 attccatgtg accattgggc acacggcact gtctctttac actgactgcc 950

 ccttccccaa atggatgcac tgggctctaa ttgcctatgc aatcagcttc 1000

 atatttctct ttcttaactt ctacattcgg acatacaaag agcctaagaa 1050

 accaaaagct ggaaaaacag ccatgaatgg tatttcagca aatggtgtga 1100

 gcaaatcaga aaaacaactc atgatagaaa atggaaaaaa gcagaaaaat 1150

 ggaaaagcaa aaggagatta aattgaactg ggccttaact gttgttgaca 1200

 gtgaggaaaa actcccatat catataaaat ttcagggaaa acagaagcaa 1250

 aggagagctt gggggtgggg agaaaagaca aatgtgctct atgtcctagt 1300

 aactcttaga ctgagtaaag tgttaatacc atacccagat gttttattta 1350

 tgaagttttt attttaaaca ttttttttaa aaattagcct tgatattctc 1400

 cagaccaaag caatcattaa gtgactttgg ggattctccc cctgttcaca 1450

 tccagttgtc taaaggatga gatttttcat gtatcttata gtcactcatt 1500

 cttcggtctg aattttagac gatcacagaa acggtcttta tgaattattt 1550

 tgataaatta ctaattatct tatctactga ctgaaatcag tggtgttaca 1600

 ttttcttgtc caaagctgaa aatgtgtata cacttaaact tgcacatttg 1650

 aattcatttg ctgaccggaa tggtcaaatc tctccacctc tagtcagagt 1700

 ataattttgg ttgtaattaa atttttaaaa tctgctgatc tctgtagaat 1750

 cttagaggct tgatgatgat ggtgttggtg aaaataagaa agaattgcag 1800

 taaagtcttg tctggtgacc cagagatcac catgacttga ggcacaaatc 1850

 actgtgggga aacaattttt tgtgatgaaa aggcagcatt tgaatactcc 1900

 tgttagtagc agaaatatat tatgaaaatt aagattattg tctgattgaa 1950

 acatgaaaca actcatgtct ttattagtaa catcataaga tagttacatt 2000

 tatgtgctgt tagaatatgt tgatttttat caggctttcc ttgttttgat 2050

 ttatggctgt tcctgatttt tcatatgtgg aaatatacct acctcttccg 2100

 ttggaaagaa catttaaaat taaataaatt ttaattaaaa aatcaaggag 2150

 tcttctaatg taaattttaa tgttaacttt caaatccact agtatttttt 2200

 ttgcttttat gacaaatagc atacaccaaa catttctgtg aaactatcct 2250

 tctctttcaa tgtgtttaat tttggagtaa cgttttcctt gtgactaagt 2300

 tgcaagatct tatttattaa ctaggtatga agtataaacc cattttggtg 2350

 caatattctt gactccttgg tgctaaagat tgttaaattc aatgcttgat 2400

 gttacaaggt gttgttaaaa cacaaaatga ataaaagtga gagtagtcag 2450

 aactataaca ttcaatttgc tatttacaaa tgaagtattt catgtaatat 2500

 aagtgaacaa ctggaaataa agtaggaaag aatttgtatc atgttttact 2550

 acataggtta attttttaag ggatgttgca aagggattac tagagaaaga 2600

 caaaatgtga ccaaaaaaaa gcatgaatat ttcttaagta tctcaacaac 2650

 atgtcaaagc tgcatgtgta ggatgtatgc tgtttgtaca aactatttca 2700

 gaatattttg taagctataa catatttatt gtgcattaaa attaaatact 2750

 ttttccccaa aggcatgcag tcatgagaat tacagaaaat ttgcaacata 2800

 taaagtagtt tgatctaaga ggattcaaca cctttgtttt gttgctcagt 2850

 gtgtaatgac tgagatttgt aaatctttgt gaacattctg tactggttcc 2900

 caagagctat tcattccctg ctacctgatt tcagcacaat aaatatactt 2950

 ctgctgtggg aaaaataaaa aaaaaaaaaa aaaaaaaaaa aa 2992

<210> 3428
<211> 314
<212> PRT
<213> Homo sapien

<400> 3428
 Met Gly Leu Leu Asp Ser Glu Pro Gly Ser Val Leu Asn Val Val
   1               5                  10                  15

 Ser Thr Ala Leu Asn Asp Thr Val Glu Phe Tyr Arg Trp Thr Trp
                  20                  25                  30

 Ser Ile Ala Asp Lys Arg Val Glu Asn Trp Pro Leu Met Gln Ser
                  35                  40                  45

 Pro Trp Pro Thr Leu Ser Ile Ser Thr Leu Tyr Leu Leu Phe Val
                  50                  55                  60

 Trp Leu Gly Pro Lys Trp Met Lys Asp Arg Glu Pro Phe Gln Met
                  65                  70                  75

 Arg Leu Val Leu Ile Ile Tyr Asn Phe Gly Met Val Leu Leu Asn
                  80                  85                  90

 Leu Phe Ile Phe Arg Glu Leu Phe Met Gly Ser Tyr Asn Ala Gly
                  95                 100                 105

 Tyr Ser Tyr Ile Cys Gln Ser Val Asp Tyr Ser Asn Asn Val His
                 110                 115                 120

 Glu Val Arg Ile Ala Ala Ala Leu Trp Trp Tyr Phe Val Ser Lys
                 125                 130                 135

 Gly Val Glu Tyr Leu Asp Thr Val Phe Phe Ile Leu Arg Lys Lys
                 140                 145                 150

 Asn Asn Gln Val Ser Phe Leu His Val Tyr His His Cys Thr Met
                 155                 160                 165

 Phe Thr Leu Trp Trp Ile Gly Ile Lys Trp Val Ala Gly Gly Gln
                 170                 175                 180

 Ala Phe Phe Gly Ala Gln Leu Asn Ser Phe Ile His Val Ile Met
                 185                 190                 195

 Tyr Ser Tyr Tyr Gly Leu Thr Ala Phe Gly Pro Trp Ile Gln Lys
                 200                 205                 210

 Tyr Leu Trp Trp Lys Arg Tyr Leu Thr Met Leu Gln Leu Ile Gln
                 215                 220                 225

 Phe His Val Thr Ile Gly His Thr Ala Leu Ser Leu Tyr Thr Asp
                 230                 235                 240

 Cys Pro Phe Pro Lys Trp Met His Trp Ala Leu Ile Ala Tyr Ala
                 245                 250                 255

 Ile Ser Phe Ile Phe Leu Phe Leu Asn Phe Tyr Ile Arg Thr Tyr
                 260                 265                 270

 Lys Glu Pro Lys Lys Pro Lys Ala Gly Lys Thr Ala Met Asn Gly
                 275                 280                 285

 Ile Ser Ala Asn Gly Val Ser Lys Ser Glu Lys Gln Leu Met Ile
                 290                 295                 300

 Glu Asn Gly Lys Lys Gln Lys Asn Gly Lys Ala Lys Gly Asp
                 305                 310

<210> 3429
<211> 3205
<212> DNA
<213> Homo sapien

<400> 3429
 agcgggagtc tttcgttctg ggaggcccag gcggcttcgc gttctgagaa 50

 taaacagaac ctctgttgct ctgcgacttg caggcactgg gagattcgta 100

 gctaagacgc cagggcatcc cggaagctgg gaaatgggac tgttgacatt 150

 cagggatgtg gccgtagaat tctctttgga ggagtgggaa cacctggaac 200

 cagctcagaa gaatttgtat cagaatgtga tgttagaaaa ctacagaaac 250

 ctggtctctc tgggtcttgt tgtctctaag ccggacctga tcaccttttt 300

 ggaacaaagg aaagagcctt ggaatgtgaa gagtgaggag acagtagcca 350

 tccagccaga tgtgttttcg cattataaca aggacctgtt gacagagcac 400

 tgcacagaag cttcattcca aaaagtgata tcgaggagac atgggagctg 450

 tgatcttgag aatttacatt taagaaaaag gtggaaaagg gaggagtgtg 500

 aagggcacaa tggatgttat gatgaaaaga cttttaaata tgatcaattt 550

 gatgaatcct ctgttgaaag tttgtttcac cagcaaatac tttcttcttg 600

 tgccaaaagc tataactttg atcaatatag gaaggtcttt actcattcat 650

 cattgcttaa tcaacaagag gaaatagata tttggggaaa acatcacata 700

 tatgataaaa cttcagtgtt atttaggcag gtctctactc taaatagtta 750

 ccgaaatgtt tttattggag agaaaaatta tcattgcaat aattctgaaa 800

 aaaccttgaa ccaaagctca agccctaaaa atcatcagga aaattatttt 850

 ctagaaaaac aatacaaatg taaagaattt gaggaagtct ttcttcagag 900

 tatgcatggg caagagaaac aagaacagtc ttacaaatgt aataaatgtg 950

 tagaagtttg tacccagtca ttaaaacata ttcaacatca gaccatccat 1000

 atcagagaaa actcatatag ctataacaaa tatgataaag atcttagtca 1050

 gtcatcaaat cttagaaagc agataatcca taatgaagag aaaccataca 1100

 aatgtgaaaa atgtggggat agcttaaacc atagtttgca ccttactcaa 1150

 catcagatca ttcctaccga agagaaaccc tataaatgga aagaatgtgg 1200

 caaggtcttt aaccttaact gtagtttata ccttactaaa cagcagcaaa 1250

 ttgatactgg agaaaacctt tacaaatgta aagcatgtag caaatctttt 1300

 actcgttcct ccaatcttat tgtgcatcag agaattcaca ctggagagaa 1350

 accatacaaa tgtaaagaat gtggcaaagc ctttcgctgt agttcatacc 1400

 ttactaaaca taagcgaatt catactggag agaaacctta taaatgtaaa 1450

 gaatgtggaa aagcttttaa ccgtagttca tgccttactc aacatcagac 1500

 aactcataca ggagaaaaac tttacaaatg taaagtatgt agcaaatctt 1550

 atgctcgttc ttcaaatctt attatgcatc agagagttca tactggagag 1600

 aagccttata aatgtaaaga atgtggcaaa gtctttagcc gtagttcttg 1650

 ccttactcaa catcggaaaa ttcatactgg agaaaatctt tacaaatgca 1700

 aagtatgtgc taaacctttt acttgtttct caaatcttat tgtgcatgag 1750

 agaattcata ctggagagaa accctataaa tgtaaagaat gtggcaaagc 1800

 ctttccttat agttcacacc ttattcgaca tcatcgaatt catactggag 1850

 aaaaaccata caaatgtaaa gcatgtagca aatcttttag tgactcctca 1900

 ggtcttactg tgcatcggcg aactcatact ggagagaaac cctatacatg 1950

 taaagaatgt ggcaaagcct ttagttatag ttcagatgtt attcagcatc 2000

 ggagaattca tactggccag agaccctaca aatgtgaaga atgtggcaaa 2050

 gccttcaact ataggtcata cctcactaca catcagagaa gtcatactgg 2100

 agagagaccc tacaaatgtg aagaatgtgg caaagccttc aactctaggt 2150

 catacctcac tacacatcgg agaagacata ctggagagag accctacaaa 2200

 tgtgatgaat gtggtaaagc cttcagctat aggtcatacc tcactacaca 2250

 tcggagaagt catagtggag agagacccta caaatgtgaa gaatgtggca 2300

 aagcctttaa ctctaggtca tacctcattg cacatcagag aagtcatact 2350

 agagaaaaac tttaaaaatg taaaacatgg agcagatttt ttacttgtta 2400

 cccatgtctt attgtgcatc agataattta tatgggagtg aaaccctaca 2450

 aatgttaaga atgtggcata acctttaact attttcaagc cttacacaat 2500

 agcagagaat ataaactgaa aaaatccata caaatattaa aaatgtggca 2550

 aattatttta aactgtgctc aacccttact caagataatc catactagag 2600

 aaacactata gatgtaaaaa tgtgaaaagt tttattcaaa atatcaaact 2650

 tatgagtcac ctaggggttc atagaaaaag gaagtttgca gatgcaataa 2700

 atgtgaggaa gtatttaata aaaaatgaag tctaaatgtg tcagagaatt 2750

 tatgtgagaa aggactaaag cacagacact ttcagccttt atactaaata 2800

 agagtatttt ttgtacagaa taatctaaag gcaaaataat tagataattt 2850

 atttgcttat atgttttaaa gtagcaagaa cattgatgtt ttgacaggta 2900

 tatttcatag atacttcatt tgtatttaca gtatttgagg tttttggaaa 2950

 gcaaatatta tttatataat tcagctttca aatctgttgc tgcttttcct 3000

 taatccgtgg tgttcatgtg aaaatatgtg ttctgttttt ttttctgcat 3050

 cagaacaatg tgaggtcatt ctacgttaat atcattaata tcagcatttt 3100

 tcatggaagt ttaatgccaa atgtaaaaca catgaaaatt tttaaaaata 3150

 tgctctttgt gtttgaataa agtagtaatg cacgtaaaca aaaaaaaaaa 3200

 aaaaa 3205

<210> 3430
<211> 743
<212> PRT
<213> Homo sapien

<400> 3430
 Met Gly Leu Leu Thr Phe Arg Asp Val Ala Val Glu Phe Ser Leu
   1               5                  10                  15

 Glu Glu Trp Glu His Leu Glu Pro Ala Gln Lys Asn Leu Tyr Gln
                  20                  25                  30

 Asn Val Met Leu Glu Asn Tyr Arg Asn Leu Val Ser Leu Gly Leu
                  35                  40                  45

 Val Val Ser Lys Pro Asp Leu Ile Thr Phe Leu Glu Gln Arg Lys
                  50                  55                  60

 Glu Pro Trp Asn Val Lys Ser Glu Glu Thr Val Ala Ile Gln Pro
                  65                  70                  75

 Asp Val Phe Ser His Tyr Asn Lys Asp Leu Leu Thr Glu His Cys
                  80                  85                  90

 Thr Glu Ala Ser Phe Gln Lys Val Ile Ser Arg Arg His Gly Ser
                  95                 100                 105

 Cys Asp Leu Glu Asn Leu His Leu Arg Lys Arg Trp Lys Arg Glu
                 110                 115                 120

 Glu Cys Glu Gly His Asn Gly Cys Tyr Asp Glu Lys Thr Phe Lys
                 125                 130                 135

 Tyr Asp Gln Phe Asp Glu Ser Ser Val Glu Ser Leu Phe His Gln
                 140                 145                 150

 Gln Ile Leu Ser Ser Cys Ala Lys Ser Tyr Asn Phe Asp Gln Tyr
                 155                 160                 165

 Arg Lys Val Phe Thr His Ser Ser Leu Leu Asn Gln Gln Glu Glu
                 170                 175                 180

 Ile Asp Ile Trp Gly Lys His His Ile Tyr Asp Lys Thr Ser Val
                 185                 190                 195

 Leu Phe Arg Gln Val Ser Thr Leu Asn Ser Tyr Arg Asn Val Phe
                 200                 205                 210

 Ile Gly Glu Lys Asn Tyr His Cys Asn Asn Ser Glu Lys Thr Leu
                 215                 220                 225

 Asn Gln Ser Ser Ser Pro Lys Asn His Gln Glu Asn Tyr Phe Leu
                 230                 235                 240

 Glu Lys Gln Tyr Lys Cys Lys Glu Phe Glu Glu Val Phe Leu Gln
                 245                 250                 255

 Ser Met His Gly Gln Glu Lys Gln Glu Gln Ser Tyr Lys Cys Asn
                 260                 265                 270

 Lys Cys Val Glu Val Cys Thr Gln Ser Leu Lys His Ile Gln His
                 275                 280                 285

 Gln Thr Ile His Ile Arg Glu Asn Ser Tyr Ser Tyr Asn Lys Tyr
                 290                 295                 300

 Asp Lys Asp Leu Ser Gln Ser Ser Asn Leu Arg Lys Gln Ile Ile
                 305                 310                 315

 His Asn Glu Glu Lys Pro Tyr Lys Cys Glu Lys Cys Gly Asp Ser
                 320                 325                 330

 Leu Asn His Ser Leu His Leu Thr Gln His Gln Ile Ile Pro Thr
                 335                 340                 345

 Glu Glu Lys Pro Tyr Lys Trp Lys Glu Cys Gly Lys Val Phe Asn
                 350                 355                 360

 Leu Asn Cys Ser Leu Tyr Leu Thr Lys Gln Gln Gln Ile Asp Thr
                 365                 370                 375

 Gly Glu Asn Leu Tyr Lys Cys Lys Ala Cys Ser Lys Ser Phe Thr
                 380                 385                 390

 Arg Ser Ser Asn Leu Ile Val His Gln Arg Ile His Thr Gly Glu
                 395                 400                 405

 Lys Pro Tyr Lys Cys Lys Glu Cys Gly Lys Ala Phe Arg Cys Ser
                 410                 415                 420

 Ser Tyr Leu Thr Lys His Lys Arg Ile His Thr Gly Glu Lys Pro
                 425                 430                 435

 Tyr Lys Cys Lys Glu Cys Gly Lys Ala Phe Asn Arg Ser Ser Cys
                 440                 445                 450

 Leu Thr Gln His Gln Thr Thr His Thr Gly Glu Lys Leu Tyr Lys
                 455                 460                 465

 Cys Lys Val Cys Ser Lys Ser Tyr Ala Arg Ser Ser Asn Leu Ile
                 470                 475                 480

 Met His Gln Arg Val His Thr Gly Glu Lys Pro Tyr Lys Cys Lys
                 485                 490                 495

 Glu Cys Gly Lys Val Phe Ser Arg Ser Ser Cys Leu Thr Gln His
                 500                 505                 510

 Arg Lys Ile His Thr Gly Glu Asn Leu Tyr Lys Cys Lys Val Cys
                 515                 520                 525

 Ala Lys Pro Phe Thr Cys Phe Ser Asn Leu Ile Val His Glu Arg
                 530                 535                 540

 Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Glu Cys Gly Lys
                 545                 550                 555

 Ala Phe Pro Tyr Ser Ser His Leu Ile Arg His His Arg Ile His
                 560                 565                 570

 Thr Gly Glu Lys Pro Tyr Lys Cys Lys Ala Cys Ser Lys Ser Phe
                 575                 580                 585

 Ser Asp Ser Ser Gly Leu Thr Val His Arg Arg Thr His Thr Gly
                 590                 595                 600

 Glu Lys Pro Tyr Thr Cys Lys Glu Cys Gly Lys Ala Phe Ser Tyr
                 605                 610                 615

 Ser Ser Asp Val Ile Gln His Arg Arg Ile His Thr Gly Gln Arg
                 620                 625                 630

 Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Tyr Arg Ser
                 635                 640                 645

 Tyr Leu Thr Thr His Gln Arg Ser His Thr Gly Glu Arg Pro Tyr
                 650                 655                 660

 Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Ser Arg Ser Tyr Leu
                 665                 670                 675

 Thr Thr His Arg Arg Arg His Thr Gly Glu Arg Pro Tyr Lys Cys
                 680                 685                 690

 Asp Glu Cys Gly Lys Ala Phe Ser Tyr Arg Ser Tyr Leu Thr Thr
                 695                 700                 705

 His Arg Arg Ser His Ser Gly Glu Arg Pro Tyr Lys Cys Glu Glu
                 710                 715                 720

 Cys Gly Lys Ala Phe Asn Ser Arg Ser Tyr Leu Ile Ala His Gln
                 725                 730                 735

 Arg Ser His Thr Arg Glu Lys Leu
                 740

<210> 3431
<211> 1196
<212> DNA
<213> Homo sapien

<400> 3431
 agccgagggc tgcacaaaga ccttcctggc ctgccccaga cagagctgag 50

 gacccctggc cgtgggcttg ggcctcggct tcacaggatg gggctgccag 100

 tgtcctgggc ccctcctgcc ctctgggttc tagggtgctg cgccctgctc 150

 ctctcgctgt gggcgctgtg cacagcctgc cgcaggcccg aggacgctgt 200

 agcccccagg aagagggcgc ggaggcagcg ggcgaggctg cagggcagtg 250

 cgacggcggc ggaagcgtcc ctactgaggc ggacccacct ctgctccctc 300

 agcaagtcgg acaccagact gcacgagctg caccggggcc cgcgcagcag 350

 cagggccctg cggcctgcca gcatggatct cctgcgccca cactggctgg 400

 aggtgtccag ggacatcacc ggaccgcagg cagccccctc tgccttccca 450

 caccaggagc tgccccgggc tctgccggca gctgcagcca ccgcagggtg 500

 cgctggcctc gaggccacct attccaacgt ggggctggcg gcccttcccg 550

 gggtcagcct ggcggccagc cctgtggtgg ccgagtatgc ccgcgtccag 600

 aagcgcaaag ggacccatcg cagtccccaa gagccacagc aggggaagac 650

 tgaggtgacc ccggccgctc aggtggacgt cctgtactcc agggtctgca 700

 agcctaaaag gagggaccca ggacccacca cagacccgct ggaccccaag 750

 ggccagggag cgattctggc cctggcgggt gacctggcct accagaccct 800

 cccgctcagg gccctggatg tgggcagcgg ccccctggaa aacgtgtatg 850

 agagcatccg ggagctgggg gaccctgctg gcaggagcag cacgtgcggg 900

 gctgggacgc cccctgcttc cagctgcccc agcctaggga ggggctggag 950

 acccctccct gcctccctgc cctgaacact caaggacctg tgctccttcc 1000

 tccagagtga ggcccgtccc ccgccccgcc ccgcctcaca gctgacagcg 1050

 ccagtcccag gtccccgggc tgccagcccg tgaggtccgt gaggtcctgg 1100

 ccgctctgac agccgcggcc tccccgggct ccagagaagg cccgcgtcta 1150

 aataaagcgc cagcgcagga tgaaagcgaa aaaaaaaaaa aaaaaa 1196

<210> 3432
<211> 295
<212> PRT
<213> Homo sapien

<400> 3432
 Met Gly Leu Pro Val Ser Trp Ala Pro Pro Ala Leu Trp Val Leu
   1               5                  10                  15

 Gly Cys Cys Ala Leu Leu Leu Ser Leu Trp Ala Leu Cys Thr Ala
                  20                  25                  30

 Cys Arg Arg Pro Glu Asp Ala Val Ala Pro Arg Lys Arg Ala Arg
                  35                  40                  45

 Arg Gln Arg Ala Arg Leu Gln Gly Ser Ala Thr Ala Ala Glu Ala
                  50                  55                  60

 Ser Leu Leu Arg Arg Thr His Leu Cys Ser Leu Ser Lys Ser Asp
                  65                  70                  75

 Thr Arg Leu His Glu Leu His Arg Gly Pro Arg Ser Ser Arg Ala
                  80                  85                  90

 Leu Arg Pro Ala Ser Met Asp Leu Leu Arg Pro His Trp Leu Glu
                  95                 100                 105

 Val Ser Arg Asp Ile Thr Gly Pro Gln Ala Ala Pro Ser Ala Phe
                 110                 115                 120

 Pro His Gln Glu Leu Pro Arg Ala Leu Pro Ala Ala Ala Ala Thr
                 125                 130                 135

 Ala Gly Cys Ala Gly Leu Glu Ala Thr Tyr Ser Asn Val Gly Leu
                 140                 145                 150

 Ala Ala Leu Pro Gly Val Ser Leu Ala Ala Ser Pro Val Val Ala
                 155                 160                 165

 Glu Tyr Ala Arg Val Gln Lys Arg Lys Gly Thr His Arg Ser Pro
                 170                 175                 180

 Gln Glu Pro Gln Gln Gly Lys Thr Glu Val Thr Pro Ala Ala Gln
                 185                 190                 195

 Val Asp Val Leu Tyr Ser Arg Val Cys Lys Pro Lys Arg Arg Asp
                 200                 205                 210

 Pro Gly Pro Thr Thr Asp Pro Leu Asp Pro Lys Gly Gln Gly Ala
                 215                 220                 225

 Ile Leu Ala Leu Ala Gly Asp Leu Ala Tyr Gln Thr Leu Pro Leu
                 230                 235                 240

 Arg Ala Leu Asp Val Gly Ser Gly Pro Leu Glu Asn Val Tyr Glu
                 245                 250                 255

 Ser Ile Arg Glu Leu Gly Asp Pro Ala Gly Arg Ser Ser Thr Cys
                 260                 265                 270

 Gly Ala Gly Thr Pro Pro Ala Ser Ser Cys Pro Ser Leu Gly Arg
                 275                 280                 285

 Gly Trp Arg Pro Leu Pro Ala Ser Leu Pro
                 290                 295

<210> 3433
<211> 1414
<212> DNA
<213> Homo sapien

<400> 3433
 ggcacgaggc acctcgctcg cagcctcccc agcgcagcag cccggctgtg 50

 ggcctgcggc agccgggtct tcctggtccc cacctcctgg ggccgacggg 100

 cggcaggaag gggctcggcg ggacgcgccg tcagggacct gaggaggaac 150

 aacggaacgc gttcggaacg gcctggactc ccgagactca cccgactcgt 200

 ggccacaccg ggagaactga agcggcagta gccggcggag acgcccgacc 250

 cgaaggccgg ctgctaggga gcagacagct gaaccgcttg ccagacgccg 300

 aaacccagtg acgccctcca ccgctccacc gtgctcccgg ctccccgccc 350

 ccgccgcccg cgggccccaa ggcgcatgcg ccgcctgtcc tggaggggcc 400

 catttccgtc cgtcgtgggg ggaggcacag tgagtccact ggggcacggc 450

 agcgtctaag ccacaagccg agcacataag ccaggtccta acggagccta 500

 tgtgtaagtc cactactggt gcaaggttgc acacttctaa gaagagcggc 550

 gtggggggct cggcgacctt cgcttcagtc gctcccccgt gcagtcccct 600

 gtgcccaaga cacagcctga tgcttgtgct ccggtgggcg gagcttggag 650

 gcggcgggaa ctgcaattgg tggctttgaa ggcgcggcga gcgggaacag 700

 ctcttgagga gtgagactgc aggagatgtg ggccgtgcca aagagatgga 750

 tgagactgtt gctgagttca tcaagaggac catcttgaaa atccccatga 800

 atgaactgac aacaatcctg aaggcctggg attttttgtc tgaaaatcaa 850

 ctgcagactg taaatttccg acagagaaag gaatctgtag ttcagcactt 900

 gatccatctg tgtgaggaaa agcgtgcaag tatcagtgat gctgccctgt 950

 tagacatcat ttatatgcaa tttcatcagc accagaaagt ttgggatgtt 1000

 tttcagatga gtaaaggacc aggtgaagat gttgaccttt ttgatatgaa 1050

 acaatttaaa aattcgttca agaaaattct tcagagagca ttaaaaaatg 1100

 tgacagtcag cttcagagaa actgaggaga atgcagtctg gattcgaatt 1150

 gcctggggaa cacagtacac aaagccaaac cagtacaaac ctacctacgt 1200

 ggtgtactac tcccagactc cgtacgcctt cacgtcctcc tccatgctga 1250

 ggcgcaatac accgcttctg ggtcaggagt tagaagctac tgggaaaatc 1300

 tacctccgac aagaggagat cattttagat attaccgaaa tgaagaaagc 1350

 ttgcaattag tgaacatgaa aggaaaataa aaattcctca cagtcaaaaa 1400

 aaaaaaaaaa aaaa 1414

<210> 3434
<211> 204
<212> PRT
<213> Homo sapien

<400> 3434
 Met Asp Glu Thr Val Ala Glu Phe Ile Lys Arg Thr Ile Leu Lys
   1               5                  10                  15

 Ile Pro Met Asn Glu Leu Thr Thr Ile Leu Lys Ala Trp Asp Phe
                  20                  25                  30

 Leu Ser Glu Asn Gln Leu Gln Thr Val Asn Phe Arg Gln Arg Lys
                  35                  40                  45

 Glu Ser Val Val Gln His Leu Ile His Leu Cys Glu Glu Lys Arg
                  50                  55                  60

 Ala Ser Ile Ser Asp Ala Ala Leu Leu Asp Ile Ile Tyr Met Gln
                  65                  70                  75

 Phe His Gln His Gln Lys Val Trp Asp Val Phe Gln Met Ser Lys
                  80                  85                  90

 Gly Pro Gly Glu Asp Val Asp Leu Phe Asp Met Lys Gln Phe Lys
                  95                 100                 105

 Asn Ser Phe Lys Lys Ile Leu Gln Arg Ala Leu Lys Asn Val Thr
                 110                 115                 120

 Val Ser Phe Arg Glu Thr Glu Glu Asn Ala Val Trp Ile Arg Ile
                 125                 130                 135

 Ala Trp Gly Thr Gln Tyr Thr Lys Pro Asn Gln Tyr Lys Pro Thr
                 140                 145                 150

 Tyr Val Val Tyr Tyr Ser Gln Thr Pro Tyr Ala Phe Thr Ser Ser
                 155                 160                 165

 Ser Met Leu Arg Arg Asn Thr Pro Leu Leu Gly Gln Glu Leu Glu
                 170                 175                 180

 Ala Thr Gly Lys Ile Tyr Leu Arg Gln Glu Glu Ile Ile Leu Asp
                 185                 190                 195

 Ile Thr Glu Met Lys Lys Ala Cys Asn
                 200

<210> 3435
<211> 1508
<212> DNA
<213> Homo sapien

<400> 3435
 gctggaggag cctcgaggct gaggctgccg gggggctgtg ggctaccggg 50

 ccgccggcgc ctcagcgatg ttttactcag ggctcctcac tgagggcggc 100

 cgcaaggaga ccgacatgcg ggaggcggcg tcactgcgac agcagcgccg 150

 gatgaagcag gcggtgcagt tcatccacaa ggactccgcc gacctgctgc 200

 ccctggacgg cctcaagaag ctgggctcgt ccaaggacat gcaacctcat 250

 aatattctgc agaggcgcct catggaaacc aacctgtcta agctccgaag 300

 cggtccccgt gtcccttggg cctctaagac gaacaaactc aatcaggcta 350

 agtctgaggg gctaaagaag tctgaggagg atgacatgat tttggtttct 400

 tgccagtgtg ctggaaagga tgtgaaagcc ttggttgaca caggctgcct 450

 atataatctc atctctttgg cctgtgtgga cagattggga ctcaaggagc 500

 atgtcaaatc ccacaagcat gaaggagaaa agctttctct accccggcat 550

 ctcaaagtag tgggccagat tgagcaccta gtgatcacac tgggctccct 600

 ccgcctggac tgcccagcag ctgtggttga tgacaatgag aaaaacttgt 650

 cccttggtct acagactctc cgatctctga agtgcatcat aaacttggat 700

 aagcaccggc tgatcatggg gaagacagac aaggaagaaa tcccttttgt 750

 ggagacagtc tctttgaatg aagacaacac ttcagaagca taactacagc 800

 ctgcagcatg tctgcacgtg tgcatgcata cacaccgggt tgacagattg 850

 agaaaactgg gtttgaacca aatgccgtag tgacttgctg tggaccaagt 900

 ccttccatct aatagaagct ccaggggctc cttcccattc agacctctct 950

 agactatagt ctatgcttag agatcttgtc tggttatggc cattgttttt 1000

 tactactttg atcacttaac ttatagacct tttttgacac tgccagtctc 1050

 acttgtggcc tatttctctg cttcttccag gaatttgctt ttattagtca 1100

 agtatagggg ctgccaggtt ctgtgtctcc atagatatat gtgcttcttt 1150

 tcctatagct aaatgtataa taaacaggaa cctgaccttt acctcctttc 1200

 agctgtttca aacaggtgcc aggataccta tgtcttagaa ttagagtttc 1250

 ttcaaattga ttcattgatt tctcaagtat ggattatgtg aaagagccca 1300

 gggacattat ccattacagt ctaactcttt catttaaagg tccagagagg 1350

 caagtgaatt gtctaagttc atatattagg tcagtgactg aagggaccaa 1400

 gaacgcagac ctgatttcca agccaagact cccatgctgc ctcatttgta 1450

 ttcaagcctt taacaggagg gcaaagaggt gagaatgtgt taaaaaaaaa 1500

 aaaaaaaa 1508

<210> 3436
<211> 241
<212> PRT
<213> Homo sapien

<400> 3436
 Met Phe Tyr Ser Gly Leu Leu Thr Glu Gly Gly Arg Lys Glu Thr
   1               5                  10                  15

 Asp Met Arg Glu Ala Ala Ser Leu Arg Gln Gln Arg Arg Met Lys
                  20                  25                  30

 Gln Ala Val Gln Phe Ile His Lys Asp Ser Ala Asp Leu Leu Pro
                  35                  40                  45

 Leu Asp Gly Leu Lys Lys Leu Gly Ser Ser Lys Asp Met Gln Pro
                  50                  55                  60

 His Asn Ile Leu Gln Arg Arg Leu Met Glu Thr Asn Leu Ser Lys
                  65                  70                  75

 Leu Arg Ser Gly Pro Arg Val Pro Trp Ala Ser Lys Thr Asn Lys
                  80                  85                  90

 Leu Asn Gln Ala Lys Ser Glu Gly Leu Lys Lys Ser Glu Glu Asp
                  95                 100                 105

 Asp Met Ile Leu Val Ser Cys Gln Cys Ala Gly Lys Asp Val Lys
                 110                 115                 120

 Ala Leu Val Asp Thr Gly Cys Leu Tyr Asn Leu Ile Ser Leu Ala
                 125                 130                 135

 Cys Val Asp Arg Leu Gly Leu Lys Glu His Val Lys Ser His Lys
                 140                 145                 150

 His Glu Gly Glu Lys Leu Ser Leu Pro Arg His Leu Lys Val Val
                 155                 160                 165

 Gly Gln Ile Glu His Leu Val Ile Thr Leu Gly Ser Leu Arg Leu
                 170                 175                 180

 Asp Cys Pro Ala Ala Val Val Asp Asp Asn Glu Lys Asn Leu Ser
                 185                 190                 195

 Leu Gly Leu Gln Thr Leu Arg Ser Leu Lys Cys Ile Ile Asn Leu
                 200                 205                 210

 Asp Lys His Arg Leu Ile Met Gly Lys Thr Asp Lys Glu Glu Ile
                 215                 220                 225

 Pro Phe Val Glu Thr Val Ser Leu Asn Glu Asp Asn Thr Ser Glu
                 230                 235                 240

 Ala


<210> 3437
<211> 1150
<212> DNA
<213> Homo sapien

<400> 3437
 atgaaaaact ggagcacaac cacacttaca ttcaatggct tttccccctg 50

 agagaacaag gcttgaactt ctatgccaaa gaactaacta catatgaaat 100

 tgaggaattc aaaaaaacaa aagaagcaat tagaagattc ctcctggctt 150

 ataaaatgat gctagaattt tttggaataa aactgactga taaaactgga 200

 aatgttgctc gggctgttaa ctggcaggaa agatttcagc atctgaatga 250

 gtcccagcac aactatttaa gaatcactcg tattcttaaa agccttggtg 300

 agcttggata tgaaagtttt aaatctcctc ttgtaaaatt tattcttcat 350

 gaagctcttg tggagaatac tattcccaat attaagcaga gtgctctaga 400

 gtattttgtt tatacaatta gagacagaag agaaaggaga aagctcctgc 450

 ggttcgccca gaaacactac acgccttcag agaactttat ctggggaccg 500

 cctcgaaaag aacagtcgga gggaagcaaa gcccagaaaa tgtcttcccc 550

 tctcgcctcc agtcataaca gtcaaacttc tatgcacaaa aaagccaagg 600

 actccaaaaa ttcctcctca gctgttcatt taaatagcaa aacagctgaa 650

 gacaaaaaag tggcaccaaa agagcctgtg gaagagacag acaggcccag 700

 cccagagccc agcaatgaag ctgccaagcc aagaaataca gagaaggaca 750

 gtaatgctga gaacatgaat tctcaacctg agaaaacagt tactactccc 800

 acagaaaaaa aggagagtgt atctcctgag aataacgaag aaggtggaaa 850

 tgataaccaa gacaatgaaa atcctggaaa tacaaattgc catgatgttg 900

 tactagtaca gtgaattatc agaaaaccca gaagccagtt taggctagag 950

 aggaaaaaac tactgtatca tttatcctaa agaacagaga tgaggtcaat 1000

 ttcaaatttt agccatctgt ttgtgatttc tgtcataagc attttgttgt 1050

 ttgttttttt attttggatg acaatgaatt gaatatctaa taaggagatt 1100

 taagataaga cccaataaat gaatgtattc tgtaaaaaaa aaaaaaaaaa 1150

<210> 3438
<211> 252
<212> PRT
<213> Homo sapien

<400> 3438
 Met Met Leu Glu Phe Phe Gly Ile Lys Leu Thr Asp Lys Thr Gly
   1               5                  10                  15

 Asn Val Ala Arg Ala Val Asn Trp Gln Glu Arg Phe Gln His Leu
                  20                  25                  30

 Asn Glu Ser Gln His Asn Tyr Leu Arg Ile Thr Arg Ile Leu Lys
                  35                  40                  45

 Ser Leu Gly Glu Leu Gly Tyr Glu Ser Phe Lys Ser Pro Leu Val
                  50                  55                  60

 Lys Phe Ile Leu His Glu Ala Leu Val Glu Asn Thr Ile Pro Asn
                  65                  70                  75

 Ile Lys Gln Ser Ala Leu Glu Tyr Phe Val Tyr Thr Ile Arg Asp
                  80                  85                  90

 Arg Arg Glu Arg Arg Lys Leu Leu Arg Phe Ala Gln Lys His Tyr
                  95                 100                 105

 Thr Pro Ser Glu Asn Phe Ile Trp Gly Pro Pro Arg Lys Glu Gln
                 110                 115                 120

 Ser Glu Gly Ser Lys Ala Gln Lys Met Ser Ser Pro Leu Ala Ser
                 125                 130                 135

 Ser His Asn Ser Gln Thr Ser Met His Lys Lys Ala Lys Asp Ser
                 140                 145                 150

 Lys Asn Ser Ser Ser Ala Val His Leu Asn Ser Lys Thr Ala Glu
                 155                 160                 165

 Asp Lys Lys Val Ala Pro Lys Glu Pro Val Glu Glu Thr Asp Arg
                 170                 175                 180

 Pro Ser Pro Glu Pro Ser Asn Glu Ala Ala Lys Pro Arg Asn Thr
                 185                 190                 195

 Glu Lys Asp Ser Asn Ala Glu Asn Met Asn Ser Gln Pro Glu Lys
                 200                 205                 210

 Thr Val Thr Thr Pro Thr Glu Lys Lys Glu Ser Val Ser Pro Glu
                 215                 220                 225

 Asn Asn Glu Glu Gly Gly Asn Asp Asn Gln Asp Asn Glu Asn Pro
                 230                 235                 240

 Gly Asn Thr Asn Cys His Asp Val Val Leu Val Gln
                 245                 250

<210> 3439
<211> 3270
<212> DNA
<213> Homo sapien

<400> 3439
 ctaagacagg tgcagacgta tgtcggcttt ggcgtatcca tcaagcttta 50

 tattgctttg attatgattt ggaggaaagt ggagaaatta aagatatgtt 100

 acttgagtgc ttcataaata ttaattatat caagaaagaa gagggaagaa 150

 gatttcttag ttgtctcttc aactggaata tcaacttcat caaaatgatc 200

 cacgggacca ttaaaaacca gttacaggga ttacaaaagt ctttgatggt 250

 atacattgca gaaatttatt tcagagcttg gaaaaaggct tcagggaaaa 300

 tactggaggc gattgaaaat gattgcatcc aggacttcat gtttcacggg 350

 atacaccttc cgaggaggtc tccagtgcat tccaaagtgc gggaggttct 400

 gagttacttt caccatcaaa agaaagttcg gcagggagtg gaagagatgc 450

 tttatagatt atataagccc atcctttgga gaggattaaa ggccagaaac 500

 tctgaagttc gatcaaatgc tgcattgttg tttgttgaag catttcctat 550

 tagggatcca aaccttcatg ctattgaaat ggatagtgaa atccagaaac 600

 agtttgaaga gctctatagc cttttagaag atccttaccc gatggtccgt 650

 tccacaggga tccttggtgt ttgtaaaata acttctaagt actgggaaat 700

 gatgcccccg accattctta ttgacctcct gaagaaggtg actggggaac 750

 tggcatttga cacgagctca gctgatgttc gttgttctgt ctttaagtgt 800

 ctgccaatga ttttggacaa caaactgagc cacccattgt tagagcagct 850

 ccttccagct ctcagataca gtctccacga caattcggag aaagtgaggg 900

 tagcttttgt ggacatgctg ttgaagatca aagctgtgag ggctgctaag 950

 ttttggaaaa tatgtcccat ggagcacatt ctggttcgtc tggaaactga 1000

 ttctcgacct gtgtctcggc gcctggtgag cctcatcttt aattctttcc 1050

 tgcctgtgaa tcagccggag gaggtctggt gcgagcgctg tgtcaccctg 1100

 gtgcagatga accacgccgc tgccaggagg ttctatcagt acgcccacga 1150

 acacaccgcc tgcaccaaca tagcaaagct gattcacgtt attcgtcatt 1200

 gcttaaatgc ctgtatccag agggcagtga gagagcctcc agaggacgag 1250

 gaggaagagg acggaaggga gaaggagaat gtgactgttc tggacaaaac 1300

 actgtcagta aacgatgttg catgcatggc aggtttacta gaaatcattg 1350

 tgattctctg gaaaagtatt gacagaagta tggaaaataa taaagaggcc 1400

 aaactttaca cgattaacaa gtttgcctct gtgcttccag agtatctgaa 1450

 agtatttaag gatgatcgct gcaagatccc tttattcatg ctaatgtcct 1500

 ttatgccggc ctctgctgtc cccccattca gctgtggtgt gatttccacg 1550

 ctgagaagcc gggaggaggg cgctgtggac aagagctact gcactttgtt 1600

 ggattgcctc tgctcctggg ggcaagtggg gcacattctg gagcttgttg 1650

 acaactggct gcccacagag catgcccagg ccaagagcaa cacagcttct 1700

 aaaggtaggg tgcagatcca tgacacacgc ccagtcaaac ctgaattggc 1750

 attggtctac attgagtatc tgctgactca tccaaagaac cgcgagtgct 1800

 tgctctctgc tcctcggaag aaacttaacc atcttttgaa agcccttgaa 1850

 acgtcaaagg cagatctgga gtcacttctg cagacaccgg gtgggaagcc 1900

 tcgtggcttc agtgaagcag ctgccccgcg agcctttggt ctccactgtc 1950

 gcctgagcat ccatcttcag cacaagttct gctcagaagg aaaggtgtat 2000

 ttgtccatgt tggaagacac tggcttttgg ttagaaagca aaattttatc 2050

 ttttattcaa gatcaagaag aagactacct gaagcttcat agggtcattt 2100

 atcagcaaat tatccagacc tacctgactg tgtgtaaaga tgttgttatg 2150

 gtaggccttg gtgaccatca gtttcagatg caactcttac agcggagtct 2200

 tggaatcatg caaacagtga agggattttt ttatgtttca ttacttcttg 2250

 acattctgaa agagataact ggaagttcct tgattcagaa aacagattca 2300

 gatgaagaag ttgcaatgct gttggacaca gtccagaaag tatttcagaa 2350

 aatgttggaa tgtattgcac ggagcttcag gaagcagccg gaagaaggcc 2400

 tgcggctgct ttattctgtt cagaggcctc ttcatgagtt cattactgct 2450

 gttcagtctc ggcacacaga cacccctgtg caccggggtg tactttctac 2500

 tctgatcgct gggcctgtgg ttgagataag tcaccagcta cggaaggttt 2550

 ctgacgtaga agagcttacc cctccagagc atctttctga tcttccacca 2600

 ttttcaaggt gtttaatagg aataataata aagtcttcga atgtggtcag 2650

 gtcatttttg gatgaattaa aggcatgtgt ggcttctaat gatattgaag 2700

 gcattgtgtg cctcacggct gctgtgcata ttatcctggt tattaatgca 2750

 ggtaaacata aaagctcaaa agtgagggag gttgcagcca ctgttcacag 2800

 aaaactaaag acattcatgg aaattacttt ggaagaggat agcattgaaa 2850

 gatttctcta tgaatcatca tcaagaactc tgggagaact tttgaattca 2900

 taaccaagcc aacatctcca gacatgtaaa aatagggaaa agtgattcaa 2950

 attgaaatgc ctgtgtattt tcctattgtt tttaatgtta ataacccata 3000

 taatagggaa agggtgggat ttttttgtgg gaatgtggga aggtgggggt 3050

 tatggaggag ataactcaaa acttcttcaa ttttgcctag tgcctgcgta 3100

 aataatatat ttaatataaa ggactccagg tataaatggt gtagaaatcc 3150

 atgattccaa gaaaaaacac ttttctagca aacctggttg tttttaaaat 3200

 gacttttata tatgtaatat tgcttggaaa ctatgagtaa taaagcaatg 3250

 acaacaaaaa aaaaaaaaaa 3270

<210> 3440
<211> 935
<212> PRT
<213> Homo sapien

<400> 3440
 Met Leu Leu Glu Cys Phe Ile Asn Ile Asn Tyr Ile Lys Lys Glu
   1               5                  10                  15

 Glu Gly Arg Arg Phe Leu Ser Cys Leu Phe Asn Trp Asn Ile Asn
                  20                  25                  30

 Phe Ile Lys Met Ile His Gly Thr Ile Lys Asn Gln Leu Gln Gly
                  35                  40                  45

 Leu Gln Lys Ser Leu Met Val Tyr Ile Ala Glu Ile Tyr Phe Arg
                  50                  55                  60

 Ala Trp Lys Lys Ala Ser Gly Lys Ile Leu Glu Ala Ile Glu Asn
                  65                  70                  75

 Asp Cys Ile Gln Asp Phe Met Phe His Gly Ile His Leu Pro Arg
                  80                  85                  90

 Arg Ser Pro Val His Ser Lys Val Arg Glu Val Leu Ser Tyr Phe
                  95                 100                 105

 His His Gln Lys Lys Val Arg Gln Gly Val Glu Glu Met Leu Tyr
                 110                 115                 120

 Arg Leu Tyr Lys Pro Ile Leu Trp Arg Gly Leu Lys Ala Arg Asn
                 125                 130                 135

 Ser Glu Val Arg Ser Asn Ala Ala Leu Leu Phe Val Glu Ala Phe
                 140                 145                 150

 Pro Ile Arg Asp Pro Asn Leu His Ala Ile Glu Met Asp Ser Glu
                 155                 160                 165

 Ile Gln Lys Gln Phe Glu Glu Leu Tyr Ser Leu Leu Glu Asp Pro
                 170                 175                 180

 Tyr Pro Met Val Arg Ser Thr Gly Ile Leu Gly Val Cys Lys Ile
                 185                 190                 195

 Thr Ser Lys Tyr Trp Glu Met Met Pro Pro Thr Ile Leu Ile Asp
                 200                 205                 210

 Leu Leu Lys Lys Val Thr Gly Glu Leu Ala Phe Asp Thr Ser Ser
                 215                 220                 225

 Ala Asp Val Arg Cys Ser Val Phe Lys Cys Leu Pro Met Ile Leu
                 230                 235                 240

 Asp Asn Lys Leu Ser His Pro Leu Leu Glu Gln Leu Leu Pro Ala
                 245                 250                 255

 Leu Arg Tyr Ser Leu His Asp Asn Ser Glu Lys Val Arg Val Ala
                 260                 265                 270

 Phe Val Asp Met Leu Leu Lys Ile Lys Ala Val Arg Ala Ala Lys
                 275                 280                 285

 Phe Trp Lys Ile Cys Pro Met Glu His Ile Leu Val Arg Leu Glu
                 290                 295                 300

 Thr Asp Ser Arg Pro Val Ser Arg Arg Leu Val Ser Leu Ile Phe
                 305                 310                 315

 Asn Ser Phe Leu Pro Val Asn Gln Pro Glu Glu Val Trp Cys Glu
                 320                 325                 330

 Arg Cys Val Thr Leu Val Gln Met Asn His Ala Ala Ala Arg Arg
                 335                 340                 345

 Phe Tyr Gln Tyr Ala His Glu His Thr Ala Cys Thr Asn Ile Ala
                 350                 355                 360

 Lys Leu Ile His Val Ile Arg His Cys Leu Asn Ala Cys Ile Gln
                 365                 370                 375

 Arg Ala Val Arg Glu Pro Pro Glu Asp Glu Glu Glu Glu Asp Gly
                 380                 385                 390

 Arg Glu Lys Glu Asn Val Thr Val Leu Asp Lys Thr Leu Ser Val
                 395                 400                 405

 Asn Asp Val Ala Cys Met Ala Gly Leu Leu Glu Ile Ile Val Ile
                 410                 415                 420

 Leu Trp Lys Ser Ile Asp Arg Ser Met Glu Asn Asn Lys Glu Ala
                 425                 430                 435

 Lys Leu Tyr Thr Ile Asn Lys Phe Ala Ser Val Leu Pro Glu Tyr
                 440                 445                 450

 Leu Lys Val Phe Lys Asp Asp Arg Cys Lys Ile Pro Leu Phe Met
                 455                 460                 465

 Leu Met Ser Phe Met Pro Ala Ser Ala Val Pro Pro Phe Ser Cys
                 470                 475                 480

 Gly Val Ile Ser Thr Leu Arg Ser Arg Glu Glu Gly Ala Val Asp
                 485                 490                 495

 Lys Ser Tyr Cys Thr Leu Leu Asp Cys Leu Cys Ser Trp Gly Gln
                 500                 505                 510

 Val Gly His Ile Leu Glu Leu Val Asp Asn Trp Leu Pro Thr Glu
                 515                 520                 525

 His Ala Gln Ala Lys Ser Asn Thr Ala Ser Lys Gly Arg Val Gln
                 530                 535                 540

 Ile His Asp Thr Arg Pro Val Lys Pro Glu Leu Ala Leu Val Tyr
                 545                 550                 555

 Ile Glu Tyr Leu Leu Thr His Pro Lys Asn Arg Glu Cys Leu Leu
                 560                 565                 570

 Ser Ala Pro Arg Lys Lys Leu Asn His Leu Leu Lys Ala Leu Glu
                 575                 580                 585

 Thr Ser Lys Ala Asp Leu Glu Ser Leu Leu Gln Thr Pro Gly Gly
                 590                 595                 600

 Lys Pro Arg Gly Phe Ser Glu Ala Ala Ala Pro Arg Ala Phe Gly
                 605                 610                 615

 Leu His Cys Arg Leu Ser Ile His Leu Gln His Lys Phe Cys Ser
                 620                 625                 630

 Glu Gly Lys Val Tyr Leu Ser Met Leu Glu Asp Thr Gly Phe Trp
                 635                 640                 645

 Leu Glu Ser Lys Ile Leu Ser Phe Ile Gln Asp Gln Glu Glu Asp
                 650                 655                 660

 Tyr Leu Lys Leu His Arg Val Ile Tyr Gln Gln Ile Ile Gln Thr
                 665                 670                 675

 Tyr Leu Thr Val Cys Lys Asp Val Val Met Val Gly Leu Gly Asp
                 680                 685                 690

 His Gln Phe Gln Met Gln Leu Leu Gln Arg Ser Leu Gly Ile Met
                 695                 700                 705

 Gln Thr Val Lys Gly Phe Phe Tyr Val Ser Leu Leu Leu Asp Ile
                 710                 715                 720

 Leu Lys Glu Ile Thr Gly Ser Ser Leu Ile Gln Lys Thr Asp Ser
                 725                 730                 735

 Asp Glu Glu Val Ala Met Leu Leu Asp Thr Val Gln Lys Val Phe
                 740                 745                 750

 Gln Lys Met Leu Glu Cys Ile Ala Arg Ser Phe Arg Lys Gln Pro
                 755                 760                 765

 Glu Glu Gly Leu Arg Leu Leu Tyr Ser Val Gln Arg Pro Leu His
                 770                 775                 780

 Glu Phe Ile Thr Ala Val Gln Ser Arg His Thr Asp Thr Pro Val
                 785                 790                 795

 His Arg Gly Val Leu Ser Thr Leu Ile Ala Gly Pro Val Val Glu
                 800                 805                 810

 Ile Ser His Gln Leu Arg Lys Val Ser Asp Val Glu Glu Leu Thr
                 815                 820                 825

 Pro Pro Glu His Leu Ser Asp Leu Pro Pro Phe Ser Arg Cys Leu
                 830                 835                 840

 Ile Gly Ile Ile Ile Lys Ser Ser Asn Val Val Arg Ser Phe Leu
                 845                 850                 855

 Asp Glu Leu Lys Ala Cys Val Ala Ser Asn Asp Ile Glu Gly Ile
                 860                 865                 870

 Val Cys Leu Thr Ala Ala Val His Ile Ile Leu Val Ile Asn Ala
                 875                 880                 885

 Gly Lys His Lys Ser Ser Lys Val Arg Glu Val Ala Ala Thr Val
                 890                 895                 900

 His Arg Lys Leu Lys Thr Phe Met Glu Ile Thr Leu Glu Glu Asp
                 905                 910                 915

 Ser Ile Glu Arg Phe Leu Tyr Glu Ser Ser Ser Arg Thr Leu Gly
                 920                 925                 930

 Glu Leu Leu Asn Ser
                 935

<210> 3441
<211> 750
<212> DNA
<213> Homo sapien

<400> 3441
 ggctcccggg gctgaggtgg agccgcggga cgccggcagg gttgtggcgc 50

 agcagtctcc ttcctgcgcg cgcgcctgaa gtcggcgtgg gcgtttgaag 100

 aagctgggat acagcattta atggcattta atgaaaaatt tatgcttaag 150

 aagtaaaaat ggcaggcttc ctagataatt ttcgttggcc agaatgtgaa 200

 tgtattgact ggagtgagag aagaaatgct gtggcatctg ttgtcgcagg 250

 tatattgttt tttacaggct ggtggataat gattgatgca gctgtggtgt 300

 atcctaagcc agaacagttg aaccatgcct ttcacacatg tggtgtattt 350

 tccacattgg ctttcttcat gataaatgct gtatccaatg ctcaggtgag 400

 aggtgatagc tatgaaagcg gctgtttagg aagaacaggt gctcgagttt 450

 ggcttttcat tggtttcatg ttgatgtttg ggtcacttat tgcttccatg 500

 tggattcttt ttggtgcata tgttacccaa aatactgatg tttatccggg 550

 actagctgtg ttttttcaaa atgcacttat attttttagc actctgatct 600

 acaaatttgg aagaaccgaa gagctatgga cctgagatca cttcttaagt 650

 cacattttcc ttttgttata ttctgtttgt agataggttt tttatctctc 700

 agtacacatt gccaaatgga gtagattgta cattaaatgt tttgtttctt 750

<210> 3442
<211> 158
<212> PRT
<213> Homo sapien

<400> 3442
 Met Ala Gly Phe Leu Asp Asn Phe Arg Trp Pro Glu Cys Glu Cys
   1               5                  10                  15

 Ile Asp Trp Ser Glu Arg Arg Asn Ala Val Ala Ser Val Val Ala
                  20                  25                  30

 Gly Ile Leu Phe Phe Thr Gly Trp Trp Ile Met Ile Asp Ala Ala
                  35                  40                  45

 Val Val Tyr Pro Lys Pro Glu Gln Leu Asn His Ala Phe His Thr
                  50                  55                  60

 Cys Gly Val Phe Ser Thr Leu Ala Phe Phe Met Ile Asn Ala Val
                  65                  70                  75

 Ser Asn Ala Gln Val Arg Gly Asp Ser Tyr Glu Ser Gly Cys Leu
                  80                  85                  90

 Gly Arg Thr Gly Ala Arg Val Trp Leu Phe Ile Gly Phe Met Leu
                  95                 100                 105

 Met Phe Gly Ser Leu Ile Ala Ser Met Trp Ile Leu Phe Gly Ala
                 110                 115                 120

 Tyr Val Thr Gln Asn Thr Asp Val Tyr Pro Gly Leu Ala Val Phe
                 125                 130                 135

 Phe Gln Asn Ala Leu Ile Phe Phe Ser Thr Leu Ile Tyr Lys Phe
                 140                 145                 150

 Gly Arg Thr Glu Glu Leu Trp Thr
                 155

<210> 3443
<211> 2432
<212> DNA
<213> Homo sapien

<400> 3443
 agctgtttcc ctgtgggtcg ggttggactg acttttgaca gtcagccttc 50

 ggctgcggag ggggctcggc ggcggccggc ggagaaagtt gctccgagaa 100

 gaggctgggt cgagctgggc cgagccgggc gcgcagggcg ggcgtcgcgg 150

 gcgtcccggg cggacgcggc gcggagactg ccggcgcgtc ccgggggttc 200

 cgatttgaag accttgcttc tcatcaccca ctggattatg ccccaggctt 250

 ccctacccaa tgatcctctt gcaacacgcc gtgcttcctc cacctaagca 300

 gccctcaccc tcgcctccta tgtcagtggc caccaggtct acaggaacct 350

 tgcagcttcc accacagaag ccttttgggc aggaggcttc cttgcctctt 400

 gcaggggaag aagagttatc gaagggaggg gagcaagact gtgccctgga 450

 ggagctatgt aagcccctgt actgcaaact ctgcaatgtc accttgaact 500

 ctgcacagca agcccaggct cattatcagg gtaaaaatca tggtaagaaa 550

 ctccgaaatt actatgcagc aaatagctgt cctcctcctg ctagaatgag 600

 caatgtggtc gagcctgcag ctactccagt tgttccagtc cctccgcaga 650

 tgggctcctt taagccagga ggccgagtga tcctggccac ggagaatgat 700

 tactgtaagc tctgtgatgc ctccttcagt tccccagctg tggctcaggc 750

 tcactatcaa gggaagaatc atgccaagag gctgcggctg gcggaagctc 800

 agagtaactc attctcggaa tcctcagagc tgggtcaacg gcgggccagg 850

 aaagaaggga atgagtttaa gatgatgcct aacaggagaa atatgtatac 900

 agtacagaat aattcagcag gtccttactt caatccccgc tctcggcaga 950

 gaattccacg tgatctggcc atgtgtgtta ctccaagtgg ccagttttac 1000

 tgctcaatgt gtaatgttgg agctggcgaa gagatggaat tccggcagca 1050

 tttagagagc aagcaacata agagcaaggt gtctgaacag cggtacagga 1100

 atgagatgga gaatctggga tatgtatagt gattatcata ttaagataga 1150

 gcagcttttc ctgcctgttg tttgcctttt gtcaacttgc cctgctttgt 1200

 ggtctttttg atatgagtac attcctctgc ttaatgttaa tacatgtaac 1250

 ccacagtggt accatgagat gtcaaaacct gggggcccgg gggcggggcg 1300

 gggggaggtg ggtgtgaaga acgtgcttct taggtcataa cgcttttgca 1350

 gggtcaatgg tgttgagccg ctcatagcat gtgacctacc taccccatca 1400

 gaaataactt tttatcttgc tcaagttctg gtcaactagt agcctgacgg 1450

 cttagaactt tgactattta aaagtttcat tttcttttgc aattttagtt 1500

 ttatgtactg ttaaagaatt gtactgaatt ctttttagat cacagtaaaa 1550

 ataggttggc agagatttca gtttcccagg gcttaaccag aaccgccacc 1600

 tcaatgcatt gtcagtagaa tacattatta gaaactgtta aggtctttcc 1650

 cgggacattt ttttctgcca ttttcttttg caattgtagt tttatgtact 1700

 gttaaagaat tgtattgaat tctttttaga tcaaagtaaa aataggtcag 1750

 cagagatttc agtttcccag ggcttaacca gaaccgccac ctcaatgcat 1800

 tgtcagtagg atacattatt agaaactgtt agggtctttc ccaggacatt 1850

 tttttttctg tatcatgtct ccccatcatt gaagcgcaaa ttttcttgaa 1900

 ttcaaatact cccaatgagc ttgtatactt ccaaacagct aaacttgatt 1950

 tccagttgtg gatttcacac atataattgc cgccttcttc cctcctcttt 2000

 tttcccccct agttgaatca gcttgtctaa caagcccatt ttcatgcccc 2050

 agctgtgctg tgggttttcc aagcctcata tttgaatatt caatgagttt 2100

 aagatggata tgatttcaaa aaatagggcc gggcgcggtg gctcacgcct 2150

 gtaatcccag cactttggga ggccgaagca ggcggatcac gaggtcagga 2200

 ggtcgagatc atcctggcta acacagtgaa accccatctc tactaaaaat 2250

 acaaaacatt agccgggcgt ggtggtgggt gcctgtagtc ccagctactc 2300

 tggaggctga ggcaggagaa tggcgtgaac ccgggaggcg gagcttgcag 2350

 tgagccgaga tcgcgccact gcactccagc ctgggtgaca gagcgagact 2400

 ccgtctcaaa aaaaaaaaaa aaaaaaaaaa aa 2432

<210> 3444
<211> 289
<212> PRT
<213> Homo sapien

<400> 3444
 Met Ile Leu Leu Gln His Ala Val Leu Pro Pro Pro Lys Gln Pro
   1               5                  10                  15

 Ser Pro Ser Pro Pro Met Ser Val Ala Thr Arg Ser Thr Gly Thr
                  20                  25                  30

 Leu Gln Leu Pro Pro Gln Lys Pro Phe Gly Gln Glu Ala Ser Leu
                  35                  40                  45

 Pro Leu Ala Gly Glu Glu Glu Leu Ser Lys Gly Gly Glu Gln Asp
                  50                  55                  60

 Cys Ala Leu Glu Glu Leu Cys Lys Pro Leu Tyr Cys Lys Leu Cys
                  65                  70                  75

 Asn Val Thr Leu Asn Ser Ala Gln Gln Ala Gln Ala His Tyr Gln
                  80                  85                  90

 Gly Lys Asn His Gly Lys Lys Leu Arg Asn Tyr Tyr Ala Ala Asn
                  95                 100                 105

 Ser Cys Pro Pro Pro Ala Arg Met Ser Asn Val Val Glu Pro Ala
                 110                 115                 120

 Ala Thr Pro Val Val Pro Val Pro Pro Gln Met Gly Ser Phe Lys
                 125                 130                 135

 Pro Gly Gly Arg Val Ile Leu Ala Thr Glu Asn Asp Tyr Cys Lys
                 140                 145                 150

 Leu Cys Asp Ala Ser Phe Ser Ser Pro Ala Val Ala Gln Ala His
                 155                 160                 165

 Tyr Gln Gly Lys Asn His Ala Lys Arg Leu Arg Leu Ala Glu Ala
                 170                 175                 180

 Gln Ser Asn Ser Phe Ser Glu Ser Ser Glu Leu Gly Gln Arg Arg
                 185                 190                 195

 Ala Arg Lys Glu Gly Asn Glu Phe Lys Met Met Pro Asn Arg Arg
                 200                 205                 210

 Asn Met Tyr Thr Val Gln Asn Asn Ser Ala Gly Pro Tyr Phe Asn
                 215                 220                 225

 Pro Arg Ser Arg Gln Arg Ile Pro Arg Asp Leu Ala Met Cys Val
                 230                 235                 240

 Thr Pro Ser Gly Gln Phe Tyr Cys Ser Met Cys Asn Val Gly Ala
                 245                 250                 255

 Gly Glu Glu Met Glu Phe Arg Gln His Leu Glu Ser Lys Gln His
                 260                 265                 270

 Lys Ser Lys Val Ser Glu Gln Arg Tyr Arg Asn Glu Met Glu Asn
                 275                 280                 285

 Leu Gly Tyr Val


<210> 3445
<211> 1534
<212> DNA
<213> Homo sapien

<400> 3445
 tttgcgctcg gggaattaaa agaggggaaa aaaagcccga agaaaactca 50

 cgccccaaac aaaacgcaag gagaggaggg cgcgcggcct gcagccctcg 100

 cccgcgtccc cggccgcggc gtgatgcgcg cggaccagcc cgcgacgccc 150

 gggctgccgc tgtccccgca cctggacgct ggcgcggtgg ccgcgcccca 200

 gcctcgatcg ctcgccgcgg cgactcggcc ccaggcttcc ggcgccggtg 250

 ggggccctcg ctctccatgg ggctgaggga ctggctgaga accgtgtgct 300

 gctgctgccg gtgcgagtgc ttggaggagc gcgccctgcc tgagaaggag 350

 cccctcgtca gtgataacaa tccatattcc tcatttggag caactctggt 400

 gagggatgat gagaagaatt tatggagtat gccccatgat gtgtcccaca 450

 cagaggcaga cgacgacaga accctgtaca atttgatagt cattcgtaat 500

 cagcaggcca aagactcaga ggagtggcag aagctcaact atgatatcca 550

 taccctgcgg caggttcgaa gggaagtaag aaacagatgg aagtgcatct 600

 tagaagattt aggttttcaa aaggaagctg actctttgtt gtcagtgact 650

 aaactcagca ccatcagtga ttctaaaaac acaaggaaag ctcgagagat 700

 gttgttaaaa ctggctgaag aaaccagtat tttcccaaca agttgggagc 750

 tctcagagag atatctcttt gttgtggacc gtctcattgc acttgatgct 800

 gcagaagagt tctttaagct tgctcgtcga acttacccca agaagcctgg 850

 ggttccatgc ctggcagatg gccagaaaga actgcacctg tggggggacc 900

 tctcatgcag acttgcacat atgcagggag tattgcactg aagatctttg 950

 ctggaccttc ttctcttcag aagataattt tcaaaaggga gcaatgctgt 1000

 gaatgcagct tgcttctctc tacagattga gaagtccagc ttcaaaagtt 1050

 acttgccact taagcaagga acttgtcaag agatcatggt tcatgttact 1100

 gaaaagactt taaggatttg taaggttaat ccatagattg ctgagaacaa 1150

 tggaaatatt tttattttta cagattttgc acttctgaat tcaggttaaa 1200

 aactaacttg tatttagtct gcttagagga ctgtgacttg aaaattttta 1250

 tataccaatg agctttttgg tagcgtccac aatgtttaaa atatttcata 1300

 ggcgagatcc gtgttctcca tttattaatg cattgtagac caatttaact 1350

 gctgtgtttc aggaaaattc ttcctagttt aataagcaag ctaaaagttt 1400

 tattttttat atttagtgct taatctttgc ctcatgttat gtaaaattag 1450

 cctgcagata ttttctctca attctgtaga ctctcgcaag ataaacattc 1500

 aaacagtgaa acaaacaata aaataaataa acct 1534

<210> 3446
<211> 224
<212> PRT
<213> Homo sapien

<400> 3446
 Met Gly Leu Arg Asp Trp Leu Arg Thr Val Cys Cys Cys Cys Arg
   1               5                  10                  15

 Cys Glu Cys Leu Glu Glu Arg Ala Leu Pro Glu Lys Glu Pro Leu
                  20                  25                  30

 Val Ser Asp Asn Asn Pro Tyr Ser Ser Phe Gly Ala Thr Leu Val
                  35                  40                  45

 Arg Asp Asp Glu Lys Asn Leu Trp Ser Met Pro His Asp Val Ser
                  50                  55                  60

 His Thr Glu Ala Asp Asp Asp Arg Thr Leu Tyr Asn Leu Ile Val
                  65                  70                  75

 Ile Arg Asn Gln Gln Ala Lys Asp Ser Glu Glu Trp Gln Lys Leu
                  80                  85                  90

 Asn Tyr Asp Ile His Thr Leu Arg Gln Val Arg Arg Glu Val Arg
                  95                 100                 105

 Asn Arg Trp Lys Cys Ile Leu Glu Asp Leu Gly Phe Gln Lys Glu
                 110                 115                 120

 Ala Asp Ser Leu Leu Ser Val Thr Lys Leu Ser Thr Ile Ser Asp
                 125                 130                 135

 Ser Lys Asn Thr Arg Lys Ala Arg Glu Met Leu Leu Lys Leu Ala
                 140                 145                 150

 Glu Glu Thr Ser Ile Phe Pro Thr Ser Trp Glu Leu Ser Glu Arg
                 155                 160                 165

 Tyr Leu Phe Val Val Asp Arg Leu Ile Ala Leu Asp Ala Ala Glu
                 170                 175                 180

 Glu Phe Phe Lys Leu Ala Arg Arg Thr Tyr Pro Lys Lys Pro Gly
                 185                 190                 195

 Val Pro Cys Leu Ala Asp Gly Gln Lys Glu Leu His Leu Trp Gly
                 200                 205                 210

 Asp Leu Ser Cys Arg Leu Ala His Met Gln Gly Val Leu His
                 215                 220

<210> 3447
<211> 1026
<212> DNA
<213> Homo sapien

<400> 3447
 gagagctggc tgcgccgagc cccctgcgcg ctgcacatgg ggcgcctgac 50

 ggaagcggcg gcagcgggca gcggctctcg ggctgcaggc tgggcagggt 100

 cccctcccac gctcctgccg ctgtctccca cgtcccccag gtgcgcggcc 150

 accatggcgt ccagcgacga ggacggcacc aacggcggcg cctcggaggc 200

 cggcgaggac cgggaggctc ccggcaagcg gaggcgcctg gggttcttgg 250

 ccaccgcctg gctcaccttc tacgacatcg ccatgaccgc ggggtggttg 300

 gttctagcta ttgccatggt acgtttttat atggaaaaag gaacacacag 350

 aggtttatat aaaagtattc agaagacact taaatttttc cagacatttg 400

 ccttgcttga gatagttcac tgtttaattg gaattgtacc tacttctgtg 450

 attgtgactg gggtccaagt gagttcaaga atctttatgg tgtggctcat 500

 tactcacagt ataaaaccaa tccagaatga agagagtgtg gtgctttttc 550

 tggtcgcgtg gactgtgaca gagatcactc gctattcctt ctacacattc 600

 agccttcttg accacttgcc atacttcatt aaatgggcca gatataattt 650

 ttttatcatc ttatatcctg ttggagttgc tggtgaactt cttacaatat 700

 acgctgcctt gccgcatgtg aagaaaacag gaatgttttc aataagactt 750

 cctaacaaat acaatgtctc ttttgactac tattattttc ttcttataac 800

 catggcatca tatatacctt tgtttccaca actctatttt catatgttac 850

 gtcaaagaag aaaggtgctt catggagagg tgattgtaga aaaggatgat 900

 taaatgatct ctgcaaacaa ggtgcttttt ccagaataac caagattacc 950

 tgagtccaag ttttaataac aagaataaac aactttgtga aatatcaaaa 1000

 aaaaaaaaaa aaaaaaaaaa aaaaaa 1026

<210> 3448
<211> 288
<212> PRT
<213> Homo sapien

<400> 3448
 Met Gly Arg Leu Thr Glu Ala Ala Ala Ala Gly Ser Gly Ser Arg
   1               5                  10                  15

 Ala Ala Gly Trp Ala Gly Ser Pro Pro Thr Leu Leu Pro Leu Ser
                  20                  25                  30

 Pro Thr Ser Pro Arg Cys Ala Ala Thr Met Ala Ser Ser Asp Glu
                  35                  40                  45

 Asp Gly Thr Asn Gly Gly Ala Ser Glu Ala Gly Glu Asp Arg Glu
                  50                  55                  60

 Ala Pro Gly Lys Arg Arg Arg Leu Gly Phe Leu Ala Thr Ala Trp
                  65                  70                  75

 Leu Thr Phe Tyr Asp Ile Ala Met Thr Ala Gly Trp Leu Val Leu
                  80                  85                  90

 Ala Ile Ala Met Val Arg Phe Tyr Met Glu Lys Gly Thr His Arg
                  95                 100                 105

 Gly Leu Tyr Lys Ser Ile Gln Lys Thr Leu Lys Phe Phe Gln Thr
                 110                 115                 120

 Phe Ala Leu Leu Glu Ile Val His Cys Leu Ile Gly Ile Val Pro
                 125                 130                 135

 Thr Ser Val Ile Val Thr Gly Val Gln Val Ser Ser Arg Ile Phe
                 140                 145                 150

 Met Val Trp Leu Ile Thr His Ser Ile Lys Pro Ile Gln Asn Glu
                 155                 160                 165

 Glu Ser Val Val Leu Phe Leu Val Ala Trp Thr Val Thr Glu Ile
                 170                 175                 180

 Thr Arg Tyr Ser Phe Tyr Thr Phe Ser Leu Leu Asp His Leu Pro
                 185                 190                 195

 Tyr Phe Ile Lys Trp Ala Arg Tyr Asn Phe Phe Ile Ile Leu Tyr
                 200                 205                 210

 Pro Val Gly Val Ala Gly Glu Leu Leu Thr Ile Tyr Ala Ala Leu
                 215                 220                 225

 Pro His Val Lys Lys Thr Gly Met Phe Ser Ile Arg Leu Pro Asn
                 230                 235                 240

 Lys Tyr Asn Val Ser Phe Asp Tyr Tyr Tyr Phe Leu Leu Ile Thr
                 245                 250                 255

 Met Ala Ser Tyr Ile Pro Leu Phe Pro Gln Leu Tyr Phe His Met
                 260                 265                 270

 Leu Arg Gln Arg Arg Lys Val Leu His Gly Glu Val Ile Val Glu
                 275                 280                 285

 Lys Asp Asp


<210> 3449
<211> 1971
<212> DNA
<213> Homo sapien

<400> 3449
 aggataggaa ctggagttat tgttaatgtt acaggaagaa cacattctca 50

 aaggagaggg gggtggtggg aaactttgat tttcataggg ttttcagttt 100

 cctctcaaat gggaggatgc agcagtgccg ctacttaact gaacgtctcg 150

 acagtctgat ggggcggccc tcagccttcc ggagcagcag tgggactgac 200

 ctgtccagtg aggaagaaac actgaaccag atggaatggc ctttggggat 250

 ggaaaaaccc cagtttacgc tcatctcttc tctcagctaa cttttgtgga 300

 gccctgttcc caaactggcc tgggccagag caccgtggag gggtatttgt 350

 tgtaaatgga aggtttcgag gcccgcctgg aaatcctgaa gggtgagacc 400

 tgcagtgggc tcaggagtct gcatttgtgg gtgaccgagg gggcctcccc 450

 tccctctaga gtccacactg tggagagcat caggaaggga aaggcctgca 500

 tcttgtgctc agtgagctca tcgtctagtg aggaaggcat gtgtgaatct 550

 ctggacaagg cagcgctgag ctgttgtgga ctagtggtgc aggcaaggga 600

 ttacttctga ccaaggatgg tgagaaggtt tcccatacag actgacgtct 650

 ggattgagct ttgaagaaga aagccaggac tggagcagac gacgaggagg 700

 gaagagtttg accagatata ccatctggca tctccagcct cccctccaaa 750

 ttacatgtat aatcctatca agacattaaa gaccaatacg attgggacat 800

 taaacatgtt ggggctggca aaacgagtcg gtgcccgtct gctcctggcc 850

 tccacatcgg aggtgtatgg agatcctgaa gtccaccctc aaagtgagga 900

 ttactggggc cacgtgaatc caataggacc tcgggcctgc tacgatgaag 950

 gcaaacgtgt tgcagagacc atgtgctatg cctacatgaa gcaggaaggc 1000

 gtggaagtgc gagtggccag aatcttcaac acctttgggc cacgcatgca 1050

 catgaacgat gggcgagtag tcagcaactt catcctgcag gcgctccagg 1100

 gggagccact cacggtatac ggatccgggt ctcagacaag ggcgttccag 1150

 tacgtcagcg atctagtgaa tggcctcgtg gctctcatga acagcaacgt 1200

 cagcagcccg gtcaacctgg ggaacccaga agaacacaca atcctagaat 1250

 ttgctcagtt aattaaaaac cttgttggta gcggaagtga aattcagttt 1300

 ctctccgaag cccaggatga cccacagaaa agaaaaccag acatcaaaaa 1350

 agcaaagctg atgctggggt gggagcccgt ggtcccgctg gaggaaggtt 1400

 taaacaaagc aattcactac ttccgtaaag aactcgagta ccaggcaaat 1450

 aatcagtaca tccccaaacc aaagcctgcc agaataaaga aaggacggac 1500

 tcgccacagc tgaactcctc acttttagga cacaagacta ccattgtaca 1550

 cttgatggga tgtatttttg gctttttttt gttgtcgttt aaagaaagac 1600

 tttaacaggt gtcatgaaga acaaactgga atttcattct gaagcttgct 1650

 ttaatgaaat ggatgtgcct aaaagctccc ctcaaaaaac tgcagatttt 1700

 gccttgcact ttttgaatct ctctttttat gtaaaatagc gtagatgcat 1750

 ctctgcgtat tttcaagttt ttttatcttg ctgtgagagc atatgttgtg 1800

 actgtcgttg acagttttat ttactggttt ctttgtgaag ctgaaaagga 1850

 acattaagcg ggacaaaaaa tgccgatttt atttataaaa gtgggtactt 1900

 aataaatgag tcgttatact atgaaaaaaa aaaaaaaaaa aaaaaaaaaa 1950

 aaaaaaaaaa aaaaaaaaaa a 1971

<210> 3450
<211> 252
<212> PRT
<213> Homo sapien

<400> 3450
 Met Tyr Asn Pro Ile Lys Thr Leu Lys Thr Asn Thr Ile Gly Thr
   1               5                  10                  15

 Leu Asn Met Leu Gly Leu Ala Lys Arg Val Gly Ala Arg Leu Leu
                  20                  25                  30

 Leu Ala Ser Thr Ser Glu Val Tyr Gly Asp Pro Glu Val His Pro
                  35                  40                  45

 Gln Ser Glu Asp Tyr Trp Gly His Val Asn Pro Ile Gly Pro Arg
                  50                  55                  60

 Ala Cys Tyr Asp Glu Gly Lys Arg Val Ala Glu Thr Met Cys Tyr
                  65                  70                  75

 Ala Tyr Met Lys Gln Glu Gly Val Glu Val Arg Val Ala Arg Ile
                  80                  85                  90

 Phe Asn Thr Phe Gly Pro Arg Met His Met Asn Asp Gly Arg Val
                  95                 100                 105

 Val Ser Asn Phe Ile Leu Gln Ala Leu Gln Gly Glu Pro Leu Thr
                 110                 115                 120

 Val Tyr Gly Ser Gly Ser Gln Thr Arg Ala Phe Gln Tyr Val Ser
                 125                 130                 135

 Asp Leu Val Asn Gly Leu Val Ala Leu Met Asn Ser Asn Val Ser
                 140                 145                 150

 Ser Pro Val Asn Leu Gly Asn Pro Glu Glu His Thr Ile Leu Glu
                 155                 160                 165

 Phe Ala Gln Leu Ile Lys Asn Leu Val Gly Ser Gly Ser Glu Ile
                 170                 175                 180

 Gln Phe Leu Ser Glu Ala Gln Asp Asp Pro Gln Lys Arg Lys Pro
                 185                 190                 195

 Asp Ile Lys Lys Ala Lys Leu Met Leu Gly Trp Glu Pro Val Val
                 200                 205                 210

 Pro Leu Glu Glu Gly Leu Asn Lys Ala Ile His Tyr Phe Arg Lys
                 215                 220                 225

 Glu Leu Glu Tyr Gln Ala Asn Asn Gln Tyr Ile Pro Lys Pro Lys
                 230                 235                 240

 Pro Ala Arg Ile Lys Lys Gly Arg Thr Arg His Ser
                 245                 250

<210> 3451
<211> 1014
<212> DNA
<213> Homo sapien

<400> 3451
 ttcctcagaa acgagcaaac ctgaaagcta ctctctcagc ttcagaggga 50

 aaaaatggtt gtagatttct ggacttggga gcagacattt caagaactaa 100

 tccaagaggc aaaaccccgg gccacatgga cgctgaagtt ggatggcaac 150

 cttcagctag actgcctggc tcaagggtgg aagcaatacc aacagagagc 200

 atttggctgg ttccggtgtt cctcctgcca gcgaagttgg gcttccgcca 250

 agttgcagat tctgtgccac acgtactggg agcactggac atcccagggt 300

 caggtgcgta tgaggctctt tggccaaagg tgccagaagt gctcctggtc 350

 ccaatatgag atgcctgagt tctcctcgga tagcaccatg aggattctga 400

 gcaacctggt gcagcatata ctgaagaaat actatggaaa tggcatgagg 450

 aagtctccag aaatgccagt aatcctggaa gtgtccctgg aaggatccca 500

 tgacacagcc aattgtgagg catgcacttt gggcatatgt ggacagggct 550

 taaaaagcta catgacaaag ccgtccaaat ccctactccc ccacctaaag 600

 actgggaatt cctcacctgg aattggtgct gtgtacctcg caaaccaagc 650

 caagaaccag tcagatgagg caaaagaggc taaggggagt gggtatgaga 700

 aattagggcc cagtcgagac ccagatccac tgaacatctg tgtctttatt 750

 ttgctgcttg tatttattgt agtcaaatgc tttacatcag aatgatgaaa 800

 ataggcttgc cactttctct tattttaatt ccatggtagt caatgaactg 850

 gctgccactt taatataact gaaaattcat tttgagacca agcaggatca 900

 agtttgtaga ataaacactg gtttcctagc tatcctctga aaacagtatg 950

 aaacatgacc aagtacataa tggatttagt aataaatatt gtcgaattgc 1000

 taaaaaaaaa aaaa 1014

<210> 3452
<211> 246
<212> PRT
<213> Homo sapien

<400> 3452
 Met Val Val Asp Phe Trp Thr Trp Glu Gln Thr Phe Gln Glu Leu
   1               5                  10                  15

 Ile Gln Glu Ala Lys Pro Arg Ala Thr Trp Thr Leu Lys Leu Asp
                  20                  25                  30

 Gly Asn Leu Gln Leu Asp Cys Leu Ala Gln Gly Trp Lys Gln Tyr
                  35                  40                  45

 Gln Gln Arg Ala Phe Gly Trp Phe Arg Cys Ser Ser Cys Gln Arg
                  50                  55                  60

 Ser Trp Ala Ser Ala Lys Leu Gln Ile Leu Cys His Thr Tyr Trp
                  65                  70                  75

 Glu His Trp Thr Ser Gln Gly Gln Val Arg Met Arg Leu Phe Gly
                  80                  85                  90

 Gln Arg Cys Gln Lys Cys Ser Trp Ser Gln Tyr Glu Met Pro Glu
                  95                 100                 105

 Phe Ser Ser Asp Ser Thr Met Arg Ile Leu Ser Asn Leu Val Gln
                 110                 115                 120

 His Ile Leu Lys Lys Tyr Tyr Gly Asn Gly Met Arg Lys Ser Pro
                 125                 130                 135

 Glu Met Pro Val Ile Leu Glu Val Ser Leu Glu Gly Ser His Asp
                 140                 145                 150

 Thr Ala Asn Cys Glu Ala Cys Thr Leu Gly Ile Cys Gly Gln Gly
                 155                 160                 165

 Leu Lys Ser Tyr Met Thr Lys Pro Ser Lys Ser Leu Leu Pro His
                 170                 175                 180

 Leu Lys Thr Gly Asn Ser Ser Pro Gly Ile Gly Ala Val Tyr Leu
                 185                 190                 195

 Ala Asn Gln Ala Lys Asn Gln Ser Asp Glu Ala Lys Glu Ala Lys
                 200                 205                 210

 Gly Ser Gly Tyr Glu Lys Leu Gly Pro Ser Arg Asp Pro Asp Pro
                 215                 220                 225

 Leu Asn Ile Cys Val Phe Ile Leu Leu Leu Val Phe Ile Val Val
                 230                 235                 240

 Lys Cys Phe Thr Ser Glu
                 245

<210> 3453
<211> 2035
<212> DNA
<213> Homo sapien

<400> 3453
 attaacctcc agctttttaa gcagtttatc gatggtcgac tggcaaaact 50

 aaatgcagga aggggtttct ctgatgtatt tgaagaagag atcacttcag 100

 gtggcttttg tggagggaac ccgaggtcat atcaacaatg ggtgcataca 150

 gtcaagaaag gaggtgcact gttcaacaca gcaatgacca aagcaacccc 200

 tgctgtacgg acagcatata aatttgcaaa aaatcatgca aagctgggac 250

 taaaggaagt gaagagtaaa ctaaaacaca aggaaaatga agaagattat 300

 gggacctgtt ctagttctgt acaatataca ccagtttaca aattacacaa 350

 tgaaaaggga ggaaactcag aaaagcgtaa gcttgctcag gcacgcttaa 400

 aaaggcctct taagagcctt gatggtgctc tatatgatga tgaagatgat 450

 gatgacattg aaagagcaag caagttatct tctgaagatg gtgaagaagc 500

 ttctgcttat ctctatgaga gtgatgactc tgttgaaaca agagtgaaga 550

 ctccttactc aggtgaaatg gacttactag gagagattct tgatacattg 600

 agcacacaca gctcagatca ggggaagctg gcagctgcaa agagcttgga 650

 tttctttaga tcaatggatg acattgatta caaacctacg aataaatcta 700

 atgctcctag tgagaataac ctggctttcc tctgtggtgg ttctggtgac 750

 caagcagagt ggaatcttgg gcaagacgat agtgccctcc atggcaaaca 800

 cctccctcca tctcctagga agcgggtttc ctctagtggt ttgacagatt 850

 ctctgtttat cctgagagag gaaaacagta acaagcacct cggtgctgac 900

 aatgtgagtg accctacttc aggactggat ttccaactca cttcccctga 950

 agtttcccag actgataaag gaaaaacaga aaagagggaa acactaagcc 1000

 agatttcaga tgatctgctt atacccggtc ttgggcggca ttcatcgact 1050

 tttgttcctt gggagaaaga agggaaagaa gccaaagaga cttcagaaga 1100

 tattggactg ctccatgaag tagtgtcatt atgtcatatg acatctgact 1150

 tccaacaaag cttgaacatt tcagacaaaa acacaaatgg aaaccaaact 1200

 taaatcttgc atccaagctt ctatggagac attttgagat tcaatgcaat 1250

 ctgtataata aacagaatta tttgtaggaa tggcaactca tactatttaa 1300

 attttttttt gcatttgcaa catttttctc acttgttcat ttcgaggata 1350

 tatgaaatgc attgattttt aaatataaag cgaattctac tgtgctttta 1400

 aatcaggtac tagtttgtat gtatgtttaa agtatgtatt gaccatgaga 1450

 tttcccagtg tttggtgctt aatgccgttt attttattta agctaagaat 1500

 gcatatgtaa cccatgcaca taaccagtag ctactatact aatctggttg 1550

 agcatgaact gatcaagata tcaaaactta tcaaaactag cctgaagctg 1600

 atgaaactgt taacccacta attgccttaa tcttaaagct gttttttaag 1650

 catacttaaa taatgtatga aagtatgtat aaagtttgaa ggataagtta 1700

 ttagtgttct gcagagcaat aatgcctttt tctattcatc aaatcaaggt 1750

 caaaattcat cttttcaaga ttaaaaagct ctcttaatgg aaatatttaa 1800

 tttgcttata taaagcacta tagccatgtt ttccaaaaag tataaaatat 1850

 acacttacct ttcattcagt gaaatatagg aagtgctgaa ttacaatgtg 1900

 aagttaatga cttctgttta caaatgagac actctaacga gttttcagtc 1950

 tctctgtatg cctttgctat ttaggggtcc accccaagaa agccaaatac 2000

 aacataaacc gtcctgacaa aaaaaaaaaa aaaaa 2035

<210> 3454
<211> 339
<212> PRT
<213> Homo sapien

<400> 3454
 Met Thr Lys Ala Thr Pro Ala Val Arg Thr Ala Tyr Lys Phe Ala
   1               5                  10                  15

 Lys Asn His Ala Lys Leu Gly Leu Lys Glu Val Lys Ser Lys Leu
                  20                  25                  30

 Lys His Lys Glu Asn Glu Glu Asp Tyr Gly Thr Cys Ser Ser Ser
                  35                  40                  45

 Val Gln Tyr Thr Pro Val Tyr Lys Leu His Asn Glu Lys Gly Gly
                  50                  55                  60

 Asn Ser Glu Lys Arg Lys Leu Ala Gln Ala Arg Leu Lys Arg Pro
                  65                  70                  75

 Leu Lys Ser Leu Asp Gly Ala Leu Tyr Asp Asp Glu Asp Asp Asp
                  80                  85                  90

 Asp Ile Glu Arg Ala Ser Lys Leu Ser Ser Glu Asp Gly Glu Glu
                  95                 100                 105

 Ala Ser Ala Tyr Leu Tyr Glu Ser Asp Asp Ser Val Glu Thr Arg
                 110                 115                 120

 Val Lys Thr Pro Tyr Ser Gly Glu Met Asp Leu Leu Gly Glu Ile
                 125                 130                 135

 Leu Asp Thr Leu Ser Thr His Ser Ser Asp Gln Gly Lys Leu Ala
                 140                 145                 150

 Ala Ala Lys Ser Leu Asp Phe Phe Arg Ser Met Asp Asp Ile Asp
                 155                 160                 165

 Tyr Lys Pro Thr Asn Lys Ser Asn Ala Pro Ser Glu Asn Asn Leu
                 170                 175                 180

 Ala Phe Leu Cys Gly Gly Ser Gly Asp Gln Ala Glu Trp Asn Leu
                 185                 190                 195

 Gly Gln Asp Asp Ser Ala Leu His Gly Lys His Leu Pro Pro Ser
                 200                 205                 210

 Pro Arg Lys Arg Val Ser Ser Ser Gly Leu Thr Asp Ser Leu Phe
                 215                 220                 225

 Ile Leu Arg Glu Glu Asn Ser Asn Lys His Leu Gly Ala Asp Asn
                 230                 235                 240

 Val Ser Asp Pro Thr Ser Gly Leu Asp Phe Gln Leu Thr Ser Pro
                 245                 250                 255

 Glu Val Ser Gln Thr Asp Lys Gly Lys Thr Glu Lys Arg Glu Thr
                 260                 265                 270

 Leu Ser Gln Ile Ser Asp Asp Leu Leu Ile Pro Gly Leu Gly Arg
                 275                 280                 285

 His Ser Ser Thr Phe Val Pro Trp Glu Lys Glu Gly Lys Glu Ala
                 290                 295                 300

 Lys Glu Thr Ser Glu Asp Ile Gly Leu Leu His Glu Val Val Ser
                 305                 310                 315

 Leu Cys His Met Thr Ser Asp Phe Gln Gln Ser Leu Asn Ile Ser
                 320                 325                 330

 Asp Lys Asn Thr Asn Gly Asn Gln Thr
                 335

<210> 3455
<211> 6140
<212> DNA
<213> Homo sapien

<400> 3455
 gcggccgcag cctgagccag ggccccctcc ctcgtcagga ccggggcagc 50

 aagcaggccg ggggcaggtc cgggcaccca ccatgcgagg cgagctctgg 100

 ctcctggtgc tggtgctcag ggaggctgcc cgggcgctga gcccccagcc 150

 cggagcaggt cacgatgagg gcccaggctc tggatgggct gccaaaggga 200

 ccgtgcgggg ctggaaccgg agagcccgag agagccctgg gcatgtgtca 250

 gagccggaca ggacccagct gagccaggac ctgggtgggg gcaccctggc 300

 catggacacg ctgccagata acaggaccag ggtggtggag gacaaccaca 350

 gctattatgt gtcccgtctc tatggcccca gcgagcccca cagccgggaa 400

 ctgtgggtag atgtggccga ggccaaccgg agccaagtga agatccacac 450

 aatactctcc aacacccacc ggcaggcttc gagagtggtc ttgtcctttg 500

 atttcccttt ctacgggcat cctctgcggc agatcaccat agcaactgga 550

 ggcttcatct tcatggggga cgtgatccat cggatgctca cagctactca 600

 gtatgtggcg cccctgatgg ccaacttcaa ccctggctac tccgacaact 650

 ccacagttgt ttactttgac aatgggacag tctttgtggt tcagtgggac 700

 cacgtttatc tccaaggctg ggaagacaag ggcagtttca ccttccaggc 750

 agctctgcac catgacggcc gcattgtctt tgcctataaa gagatcccta 800

 tgtctgtccc ggaaatcagc tcctcccagc atcctgtcaa aaccggccta 850

 tcggatgcct tcatgattct caatccatcc ccggatgtgc cagaatctcg 900

 gcgaaggagc atctttgaat accaccgcat agagctggac cccagcaagg 950

 tcaccagcat gtcggccgtg gagttcaccc cattgccgac ctgcctgcag 1000

 cataggagct gtgacgcctg catgtcctca gacctgacct tcaactgcag 1050

 ctggtgccat gtcctccaga gatgctccag tggctttgac cgctatcgcc 1100

 aggagtggat ggactatggc tgtgcacagg aggcagaggg caggatgtgc 1150

 gaggacttcc aggatgagga ccacgactca gcctcccctg acacttcctt 1200

 cagcccctat gatggagacc tcaccactac ctcctcctcc ctcttcatcg 1250

 acagcctcac cacagaagat gacaccaagt tgaatcccta tgcaggagga 1300

 gacggccttc agaacaacct gtcccccaag acaaagggca ctcctgtgca 1350

 cctgggcacc atcgtgggca tcgtgctggc agtcctcctc gtggcggcca 1400

 tcatcctggc tggaatttac atcaatggcc accccacatc caatgctgcg 1450

 ctcttcttca tcgagcgtag acctcaccac tggccagcca tgaagtttcg 1500

 cagccaccct gaccattcca cctatgcgga ggtggagccc tcgggccatg 1550

 agaaggaggg cttcatggag gctgagcagt gctgagaaca ccaagtctcc 1600

 cctttgaaga ctttgaggcc acagaaaaga cagttaaagc aaagaagaga 1650

 agtgactttt cctggcctct cccagcatgc cctgggctga gatgagatgg 1700

 tggtttatgg ctccagagct gctgttcgct tcgtcagcac accccgaata 1750

 ttgaagaggg ggccaaaaaa caaccacatg gattttttat aggaacaaca 1800

 acctaatctc atcctgtttt gatgcaaggg ttctcttctg tgtcttgtaa 1850

 ccatgaaaca gcagaagaac taacataact aactccattt ttgtttaagg 1900

 ggcctttacc tattcctgca cctaggctag gataacttta gagcactgac 1950

 ataaaacgca aaaacaggaa tcatgccgtt tgcaaaacta actctgggat 2000

 taaaggggaa gcatgtaaac agctaactgt ttttgttaaa gatttatagg 2050

 aatgaggagg tttggctatt gtcacatgac agactgttag ccaaggacaa 2100

 agaagttctg caaacctccc ctggaccctt gctggtgtcc agatgtctgc 2150

 ggttgtcagc cccttccttt cccccgacct aaacataaaa gacaaggcaa 2200

 agcccgcata attttaagac ggttctttag gacattagtc caccatcttc 2250

 ttggtttgct ggctctccga aataaagtcc ctttccttgc tccaactcct 2300

 tgtctctcaa cgtattggct atgacgcagc aagcagaatg aatttggact 2350

 cagttacagg ctgtcaatgg tctgctctgt agcagtctca gagcctcccc 2400

 gacccactac ctggagatag ccagatagcc agatgccctg ctcctggcca 2450

 cctttaaagc ccctgcatat gacacaggtt aactaaagtc aagattgggg 2500

 ctgctgcatt ccaggttccc tagactcaca agctggtcct tggccaggtg 2550

 cagtggctca cgcctgtaat cccagcactt tgggaggctg aggcaggcgg 2600

 atcacctgaa gtcagaagtt tgagaccagc ctggccaaca taattaaaat 2650

 gtctctacta aaaatacaaa aaattagctg ggtgtggtga cgcttgcctg 2700

 tatcccagct actcaggaag ctgagacacg agaatcactt gaacctggga 2750

 ggcagaggtt gcagtgagct cagatagtgc cactgcactc cagcctgggt 2800

 gacagagcga gactccgtct caaaaaaaaa aaaagaaagc agaacctcat 2850

 ggctatagag ttggcatttt agccccagct tctgtagctc tgaaagccta 2900

 aagaaggtat tctctccatc tgttaaacac agtatagtgg ctctcagccc 2950

 ttggggcatg ttatcatggg agggaagtca aataagagga gagaaaagaa 3000

 ctcaaggggg aaactgcatt tttaggcttt gctctcttac cttgcccttt 3050

 ctactcagaa ccaataactt ctgcatcaaa acatgttaca gcctgcatca 3100

 agggctttac cccaacctgc agcccagcct tccctgggtg agcttgctat 3150

 gcgcagccac atttaccatg tggggctccc tattctgatg gcctgttcgg 3200

 tgccgggttt actcactgcc ctgttctgat gtcagtgcct gtacatacct 3250

 ccaaaggcag gacttgcctg ataaatattt ttcctcctct gaactggatt 3300

 ttataggcat taaagacaag tcgggtggct agagggctcc ttgagacata 3350

 cctagcaggg aactgcaggt ggattctgtt gagaggcaaa gcacctgagt 3400

 ggttgggaca caggcagctg gcatgggagg gacttttttt gagacagggt 3450

 ctcactgtgt cgcccagggc aaggatgccc aaagacacca ggttggagag 3500

 gcacctgcca actacttgct ttccctggag cctgcatgtg cctgtggggt 3550

 ggggaggcgt aggggtctac ggctgcctga gatgggtgtg cacagtgtgt 3600

 gaagtaccta cctccttgcc ttgctggact gtcagccagt cgcagggccg 3650

 gccacaagac ccatgtctcc atctggtcat actccatagc taccaagtta 3700

 acctgctcta aactttggag aactggatct gtccaataaa cgcttatttg 3750

 gccaagcctg atggctcgtg cctgtactcc cagcactttg ggaggctgag 3800

 gtgggagggt tgcttgagcc caggggtttg agaccagctt gggcaacaac 3850

 aacaaaaatg ccaggtgtgg tggggtgcac ctgtagtccc agctactagg 3900

 gaggctgagc caggaggatc acttgagccc gggaggttga ggctgcagtg 3950

 gggggtcata atcatgccac tgtactccag cctgggtgac agagtgagac 4000

 cctgtctccg aaaaaaaaaa aaaaaaaaga acggaaaaag aaatgcttac 4050

 attgtcaggg atcctgtaga caatcattaa ctctatgaga tgcttggttc 4100

 tatttttttg ggagactttg tccaagtgtt ttggcttaag aaatccatag 4150

 gcctctcttg gtgacacatc tctagtactt tttgtcataa acaaacaggc 4200

 catctgccgc caaatacatc cactccccat gccactgaca tcctatgggt 4250

 cagccaggct tgctttgact gaggccgagg catctggaac tttctctgcc 4300

 tgcaggggct agcagcagag gcttcaccgc atcaccaccc cttcctccac 4350

 tcctgacatt ctttcccttc agggatccaa aatggttggc cgagctccca 4400

 gtgggaaaac gtgtgctaga gttggggagt gagatgagtg gtgctgtcca 4450

 tggaatcagg ccacagcagg aactgcccca ctggccattt gagacacaca 4500

 caggtggtaa atgctctgct ggtgggctgt gcttccctca ttcagagagc 4550

 tctgttacag cccactgtgt cctttagaag cttgaaagga acccaactct 4600

 ttgctgcact gtcctttttc ttcctcaaat tcagaccctc cttccaccgg 4650

 caccccccta ctccaccctc agctcttcct tgcctggttt atcaagcaga 4700

 gctgaggccc cacgtttcca actctgattg tcacttgcat cttcacaaag 4750

 gataaaccac ggagcaactg gaaaaccatc agccaagcgt tcggatgagt 4800

 ctggttattg gtccaccccc gaccagattc ccttacactt aactcacttc 4850

 tttctttggc aatgaccctc atgacatgta taaatgggta tgactaagaa 4900

 gaggctgtga tctaacattt atttgctgcc attttttact ctggggagaa 4950

 gcagccccaa ctcatcactg ggaaagaact ccccctgcaa accagctaaa 5000

 tttgataatt taaaccccct gcccctaaaa cttctcacag agctggggag 5050

 ttggtggcaa ctttccaagt caaggtcttg cttagaaagt ccttcactac 5100

 atggccaggt gcagtggctc acgcctgtag tcccaggtac ttgggagcct 5150

 gaggcaggag gattgcttga gctcaggagt tcaaggctgc agagagctat 5200

 gatcatccca ctgcatttgt ttaaaaataa atttttaaaa tttgtgtgtt 5250

 ttatcagggg tctcctgtac agtgtatctg tgtatgtttg tgtgtgtgtt 5300

 tgtatacagc cttgtttaat gttttgagca ataagatatg cacacacagg 5350

 tattttgttg ctaaagagat tggacaaggt tgtagctgtg ctcaggcttc 5400

 agcttggttt gttaaattga gagataaaca atgacaagag ctgccagcca 5450

 accacactat tcaaaaagca aagtgttcac cactaaagct aaccattcat 5500

 ctggttgcag gcaaggctaa ggctctctct cctctagttc ctggaacaga 5550

 ctcacagatt ggcatgaagc actgatcagg ggctgcactc agactccctg 5600

 gccaagcaaa cctacaccag aagagtcagt gtcacagata tgatgcggcc 5650

 aatctctgtc tccaaaaacc tacctgaact taatggtaga attcaaagat 5700

 ctggggactg agggcaccca gccttctaaa acacaatgta ttcatgtgtt 5750

 tagtgtaaac tctctgcatg gattctcagt gttaataata aaaggaagca 5800

 ttcttttaca actcctgctg tgtgcaaaag aaagtgcaaa ggatttggag 5850

 tggcattccg aagatcacca cacatacctt ggttctgatg gctgctgaac 5900

 tccgacttct tcgctgagac atgactgtgg gaacagcctc cagctatctg 5950

 ctcatcagag gtgctttcct caacctcctg caccacctcc aagagaaaca 6000

 gcctaaaaag aaaccccagc tgtttactta tattggtctg taaatccctg 6050

 gaagtaaacc ccatgcattt ttatctactg tctgaggaca tacaataaat 6100

 ctgagaaagt ctatgctgtc aaaaaaaaaa aaaaaaaaaa 6140

<210> 3456
<211> 500
<212> PRT
<213> Homo sapien

<400> 3456
 Met Arg Gly Glu Leu Trp Leu Leu Val Leu Val Leu Arg Glu Ala
   1               5                  10                  15

 Ala Arg Ala Leu Ser Pro Gln Pro Gly Ala Gly His Asp Glu Gly
                  20                  25                  30

 Pro Gly Ser Gly Trp Ala Ala Lys Gly Thr Val Arg Gly Trp Asn
                  35                  40                  45

 Arg Arg Ala Arg Glu Ser Pro Gly His Val Ser Glu Pro Asp Arg
                  50                  55                  60

 Thr Gln Leu Ser Gln Asp Leu Gly Gly Gly Thr Leu Ala Met Asp
                  65                  70                  75

 Thr Leu Pro Asp Asn Arg Thr Arg Val Val Glu Asp Asn His Ser
                  80                  85                  90

 Tyr Tyr Val Ser Arg Leu Tyr Gly Pro Ser Glu Pro His Ser Arg
                  95                 100                 105

 Glu Leu Trp Val Asp Val Ala Glu Ala Asn Arg Ser Gln Val Lys
                 110                 115                 120

 Ile His Thr Ile Leu Ser Asn Thr His Arg Gln Ala Ser Arg Val
                 125                 130                 135

 Val Leu Ser Phe Asp Phe Pro Phe Tyr Gly His Pro Leu Arg Gln
                 140                 145                 150

 Ile Thr Ile Ala Thr Gly Gly Phe Ile Phe Met Gly Asp Val Ile
                 155                 160                 165

 His Arg Met Leu Thr Ala Thr Gln Tyr Val Ala Pro Leu Met Ala
                 170                 175                 180

 Asn Phe Asn Pro Gly Tyr Ser Asp Asn Ser Thr Val Val Tyr Phe
                 185                 190                 195

 Asp Asn Gly Thr Val Phe Val Val Gln Trp Asp His Val Tyr Leu
                 200                 205                 210

 Gln Gly Trp Glu Asp Lys Gly Ser Phe Thr Phe Gln Ala Ala Leu
                 215                 220                 225

 His His Asp Gly Arg Ile Val Phe Ala Tyr Lys Glu Ile Pro Met
                 230                 235                 240

 Ser Val Pro Glu Ile Ser Ser Ser Gln His Pro Val Lys Thr Gly
                 245                 250                 255

 Leu Ser Asp Ala Phe Met Ile Leu Asn Pro Ser Pro Asp Val Pro
                 260                 265                 270

 Glu Ser Arg Arg Arg Ser Ile Phe Glu Tyr His Arg Ile Glu Leu
                 275                 280                 285

 Asp Pro Ser Lys Val Thr Ser Met Ser Ala Val Glu Phe Thr Pro
                 290                 295                 300

 Leu Pro Thr Cys Leu Gln His Arg Ser Cys Asp Ala Cys Met Ser
                 305                 310                 315

 Ser Asp Leu Thr Phe Asn Cys Ser Trp Cys His Val Leu Gln Arg
                 320                 325                 330

 Cys Ser Ser Gly Phe Asp Arg Tyr Arg Gln Glu Trp Met Asp Tyr
                 335                 340                 345

 Gly Cys Ala Gln Glu Ala Glu Gly Arg Met Cys Glu Asp Phe Gln
                 350                 355                 360

 Asp Glu Asp His Asp Ser Ala Ser Pro Asp Thr Ser Phe Ser Pro
                 365                 370                 375

 Tyr Asp Gly Asp Leu Thr Thr Thr Ser Ser Ser Leu Phe Ile Asp
                 380                 385                 390

 Ser Leu Thr Thr Glu Asp Asp Thr Lys Leu Asn Pro Tyr Ala Gly
                 395                 400                 405

 Gly Asp Gly Leu Gln Asn Asn Leu Ser Pro Lys Thr Lys Gly Thr
                 410                 415                 420

 Pro Val His Leu Gly Thr Ile Val Gly Ile Val Leu Ala Val Leu
                 425                 430                 435

 Leu Val Ala Ala Ile Ile Leu Ala Gly Ile Tyr Ile Asn Gly His
                 440                 445                 450

 Pro Thr Ser Asn Ala Ala Leu Phe Phe Ile Glu Arg Arg Pro His
                 455                 460                 465

 His Trp Pro Ala Met Lys Phe Arg Ser His Pro Asp His Ser Thr
                 470                 475                 480

 Tyr Ala Glu Val Glu Pro Ser Gly His Glu Lys Glu Gly Phe Met
                 485                 490                 495

 Glu Ala Glu Gln Cys
                 500

<210> 3457
<211> 4669
<212> DNA
<213> Homo sapien

<400> 3457
 tttttattat tgctgttatt gaggttgagg gagaagagat cggtctaaat 50

 tctggctggg taagtggggg gattctcggc gatgagaaac gggggactta 100

 gaagccggag gaaaatcagc agccccacat ctccacttct ccagtccgcc 150

 ctactctcca cccgtgacct ccagtggaga ccccaggcgg cagcatcagt 200

 atttgatcgg cccttcgtca gcacgctgcc agccctggcc ggctgggttc 250

 gccaggcatc acccgctcgg ctctgaagcg gacgcctggc cctgcaccgg 300

 gctttggaag gaccctctct gcgctcgccc cctccccagg gtggctccgc 350

 tttcgagccc gggcgcggcg cccaccatgc gcggctgcct gcggctcgcg 400

 ctgctctgcg cgctgccctg gctcctgctg gcggcgtcgc ccgggcaccc 450

 ggcgaaatcc cccaggcagc ccccggcacc gcgccgcgac cccttcgacg 500

 ctgccagggg cgccgatttc gatcatgtct acagcggggt ggtgaacctc 550

 agcaccgaga acatctactc tttcaactac accagccagc ccgaccaggt 600

 gacagccgtg agggtgtatg tgaacagttc ctctgagaat ctcaactacc 650

 cggtccttgt tgtggttcgc cagcagaaag aggtgctgtc ctggcaggtt 700

 cctctgctct tccaaggact ataccagagg agctacaatt atcaagaagt 750

 gagccgcacc ttatgtccct cagaagcaac caatgagacg ggacccttgc 800

 agcaactgat atttgtagat gtcgcatcca tggcacccct gggtgctcag 850

 tacaaactgc tagttaccaa gctgaagcac ttccagctcc ggacaaatgt 900

 tgcctttcac tttactgcca gcccctctca acctcagtat tttctataca 950

 agtttcccaa agacgtggac tcagttatca ttaaagtggt gtctgaaatg 1000

 gcttatccat gttctgttgt ctcagtccag aatatcatgt gcccggtgta 1050

 tgatctcgac cacaatgtgg aatttaatgg tgtctatcag tccatgacca 1100

 agaaagctgc catcacgcta cagaagaagg attttccagg cgagcagttc 1150

 ttcgtggtat ttgtgataaa gcctgaagat tatgcctgtg gaggatcttt 1200

 cttcatccag gaaaaggaaa accagacctg gaatctacag cgaaaaaaga 1250

 accttgaagt gaccattgtc ccttccatta aagaatctgt ttatgtgaaa 1300

 tccagtcttt tcagtgtctt catcttcctg tccttctact tgggatgcct 1350

 tcttgttggg tttgttcatt atctgaggtt tcagagaaaa tccattgatg 1400

 gaagctttgg gtccaatgat ggctctggaa atatggtggc atctcatccc 1450

 attgctgcca gcacacccga agggagcaat tatgggacaa tagatgagtc 1500

 aagctccagt cctggaaggc agatgtcctc ctccgatggt gggccaccgg 1550

 gccagtcaga cacagacagc tccgtggagg agagcgactt cgacaccatg 1600

 ccagacattg agagtgataa aaacatcatc cggaccaaga tgttccttta 1650

 cctgtcagat ttgtccagga aggaccggag aattgtcagc aaaaaatata 1700

 aaatttattt ttggaacatc atcaccattg ctgtgtttta cgcgctgccc 1750

 gtgatccagc tggtcattac ctatcagaca gtggtaaatg tcactggcaa 1800

 ccaggacatc tgttactaca acttcctctg tgctcacccc ttgggcgtcc 1850

 tgagtgcctt caacaacatt ctcagcaatc tgggccacgt gcttctgggc 1900

 ttcctcttcc tgctgatagt cttgcgccgc gacatcctcc atcggagagc 1950

 cctggaagcc aaggacatct ttgctgtgga gtacgggatt cccaaacact 2000

 ttggtctctt ctacgctatg ggcattgcat tgatgatgga aggggtgctc 2050

 agtgcttgct accatgtctg ccctaattat tccaacttcc gattcgacac 2100

 ctccttcatg tacatgatcg ctggcctgtg catgctgaag ctctatcaga 2150

 cccgccaccc agacatcaat gccagcgcct actctgccta tgcctccttt 2200

 gctgtggtca tcatggtcac cgtccttgga gtggtgtttg gaaaaaatga 2250

 cgtatggttc tgggtcatct tctctgcaat ccacgttctg gcctcgctag 2300

 ccctcagcac ccagatatat tatatgggtc gtttcaagat agatttggga 2350

 attttccggc gggctgccat ggtgttctac acagactgta tccagcagtg 2400

 tagccgacct ctatatatgg atagaatggt gttgctggtt gtggggaatc 2450

 tggttaactg gtccttcgcc ctctttggat tgatataccg ccccagggac 2500

 tttgcttcct acatgctggg catcttcatc tgtaaccttt tgctgtacct 2550

 ggccttttac atcatcatga agctccgcag ctctgaaaag gtcctcccag 2600

 tcccgctctt ctgcatcgtg gccaccgctg tgatgtgggc tgccgcccta 2650

 tattttttct tccagaatct cagcagctgg gagggaactc cggccgaatc 2700

 ccgggagaag aaccgcgagt gcattctgct ggatttcttc gatgaccatg 2750

 acatctggca cttcctctct gctactgctc tgtttttctc attcttggtt 2800

 ttgttaactt tggatgatga ccttgatgtg gttcggagag accagatccc 2850

 tgtcttctga acctccaaca ttaagagagg ggagggagcg atcaatcttg 2900

 gtgctgtttc acaaaaatta cagtgaccac agcaaagtaa ccactgccag 2950

 atgctccact caccctctgt agagccaact ctgcattcac acaggaagga 3000

 gaggggctgc gggagattta aacctgcaag aaaggaggca gaaggggagc 3050

 catgttttga ggacagacgc aaacctgagg agctgagaaa cacttgctcc 3100

 ttccatctgc agctttggga gtgcaacagg gataggcact gcatccaagt 3150

 caactcacca tcttggggtc cctcccaccc tcacggagac ttgccagcaa 3200

 tggcagaatg ctgctgcaca cttccctcca gttgtcaccc tgcccagaaa 3250

 ggccagcagc ttggacttcc tgcccagaaa ctgtgttggc ccccttcaca 3300

 cctctgcaac acctgctgct ccagcaagag gatgtgattc tttagaatat 3350

 ggcggggagg tgaccccagg ccctgcccta ctgggataga tgttttaatg 3400

 gcaccagcta gtcacctccc agaagaaact ctgtacattt cccccaggtt 3450

 tctgatgcca tcagaagggc tcaggagtgg ggtttgtcac acattcctct 3500

 taacaagtaa ctgtcactgg gaccgagtcc tgggtgctta catattcctt 3550

 cgtgtcttca tctcactgac ctgtgtggac ctcatcactc tgactctgcc 3600

 ttcttggaaa ggccctgtca ctccacagat gtctggccag cttcaaggca 3650

 gaaggaaaaa caggaaaagc tcttttaaca gcagcaggaa caagagaaat 3700

 gactaaccat actaaaagac tggtaacagc agcagcagcc agacaggcct 3750

 caccttaagg acttgggctg ccagagcaaa ttcagcagag cttatttggc 3800

 ctcccattca cacagctcag ttctgtgccc acatcacctt tggggaagaa 3850

 atcagcattc taatcaggga cactacttca ggagtcctcc acagcgagtc 3900

 cgtcatctgt cactttatgt agatcagggt tctagacttc ttccctgagg 3950

 ttctcagaag cagctctcag gatgaacgta ttgtcctctt cccctcttct 4000

 tgcaaagtgc acagctaatc taatgttgtc tctcggttgc acctgacatt 4050

 ctctccccag taaggtgttg gcaagctcag catctgggtt ccactctcac 4100

 actgtctggc agctctgtgt ctgagaagtt ctacattgac caggccccct 4150

 tgttgcctgg agtatgacgt aatcagaaaa tagacgtata aatgtgcaca 4200

 tgcgtatgta tttgcttgtg aaattaaagt cacctcttgc ctctgctttc 4250

 ctgatcattc gttagagaaa tggatcaggc atttttttaa attattattc 4300

 tttctctaaa ctatttgcat tgtgttcaaa aacccatttt agaagtttga 4350

 acagcaagct tttcctgatt ttaaaaacac aaagttgctt tcaatgaaat 4400

 attttgtgat ttttttaaag tccccaaatg tgtacttagc cttctgttat 4450

 tccttattct ttaagcagtg ttggcttcca ttgaccatat gaaggccacc 4500

 aattaaatgg ttgtgttaat ccaacatgta aaaaactttt tggcagggca 4550

 cagtggctca cgcctgtaat cccaaagtgc tggaatttac aggtaggacc 4600

 accacacttg gtccacttac ttataataaa cattgatttg gtcgttaaaa 4650

 aaaaaaaaaa aaaaaaaaa 4669

<210> 3458
<211> 827
<212> PRT
<213> Homo sapien

<400> 3458
 Met Arg Gly Cys Leu Arg Leu Ala Leu Leu Cys Ala Leu Pro Trp
   1               5                  10                  15

 Leu Leu Leu Ala Ala Ser Pro Gly His Pro Ala Lys Ser Pro Arg
                  20                  25                  30

 Gln Pro Pro Ala Pro Arg Arg Asp Pro Phe Asp Ala Ala Arg Gly
                  35                  40                  45

 Ala Asp Phe Asp His Val Tyr Ser Gly Val Val Asn Leu Ser Thr
                  50                  55                  60

 Glu Asn Ile Tyr Ser Phe Asn Tyr Thr Ser Gln Pro Asp Gln Val
                  65                  70                  75

 Thr Ala Val Arg Val Tyr Val Asn Ser Ser Ser Glu Asn Leu Asn
                  80                  85                  90

 Tyr Pro Val Leu Val Val Val Arg Gln Gln Lys Glu Val Leu Ser
                  95                 100                 105

 Trp Gln Val Pro Leu Leu Phe Gln Gly Leu Tyr Gln Arg Ser Tyr
                 110                 115                 120

 Asn Tyr Gln Glu Val Ser Arg Thr Leu Cys Pro Ser Glu Ala Thr
                 125                 130                 135

 Asn Glu Thr Gly Pro Leu Gln Gln Leu Ile Phe Val Asp Val Ala
                 140                 145                 150

 Ser Met Ala Pro Leu Gly Ala Gln Tyr Lys Leu Leu Val Thr Lys
                 155                 160                 165

 Leu Lys His Phe Gln Leu Arg Thr Asn Val Ala Phe His Phe Thr
                 170                 175                 180

 Ala Ser Pro Ser Gln Pro Gln Tyr Phe Leu Tyr Lys Phe Pro Lys
                 185                 190                 195

 Asp Val Asp Ser Val Ile Ile Lys Val Val Ser Glu Met Ala Tyr
                 200                 205                 210

 Pro Cys Ser Val Val Ser Val Gln Asn Ile Met Cys Pro Val Tyr
                 215                 220                 225

 Asp Leu Asp His Asn Val Glu Phe Asn Gly Val Tyr Gln Ser Met
                 230                 235                 240

 Thr Lys Lys Ala Ala Ile Thr Leu Gln Lys Lys Asp Phe Pro Gly
                 245                 250                 255

 Glu Gln Phe Phe Val Val Phe Val Ile Lys Pro Glu Asp Tyr Ala
                 260                 265                 270

 Cys Gly Gly Ser Phe Phe Ile Gln Glu Lys Glu Asn Gln Thr Trp
                 275                 280                 285

 Asn Leu Gln Arg Lys Lys Asn Leu Glu Val Thr Ile Val Pro Ser
                 290                 295                 300

 Ile Lys Glu Ser Val Tyr Val Lys Ser Ser Leu Phe Ser Val Phe
                 305                 310                 315

 Ile Phe Leu Ser Phe Tyr Leu Gly Cys Leu Leu Val Gly Phe Val
                 320                 325                 330

 His Tyr Leu Arg Phe Gln Arg Lys Ser Ile Asp Gly Ser Phe Gly
                 335                 340                 345

 Ser Asn Asp Gly Ser Gly Asn Met Val Ala Ser His Pro Ile Ala
                 350                 355                 360

 Ala Ser Thr Pro Glu Gly Ser Asn Tyr Gly Thr Ile Asp Glu Ser
                 365                 370                 375

 Ser Ser Ser Pro Gly Arg Gln Met Ser Ser Ser Asp Gly Gly Pro
                 380                 385                 390

 Pro Gly Gln Ser Asp Thr Asp Ser Ser Val Glu Glu Ser Asp Phe
                 395                 400                 405

 Asp Thr Met Pro Asp Ile Glu Ser Asp Lys Asn Ile Ile Arg Thr
                 410                 415                 420

 Lys Met Phe Leu Tyr Leu Ser Asp Leu Ser Arg Lys Asp Arg Arg
                 425                 430                 435

 Ile Val Ser Lys Lys Tyr Lys Ile Tyr Phe Trp Asn Ile Ile Thr
                 440                 445                 450

 Ile Ala Val Phe Tyr Ala Leu Pro Val Ile Gln Leu Val Ile Thr
                 455                 460                 465

 Tyr Gln Thr Val Val Asn Val Thr Gly Asn Gln Asp Ile Cys Tyr
                 470                 475                 480

 Tyr Asn Phe Leu Cys Ala His Pro Leu Gly Val Leu Ser Ala Phe
                 485                 490                 495

 Asn Asn Ile Leu Ser Asn Leu Gly His Val Leu Leu Gly Phe Leu
                 500                 505                 510

 Phe Leu Leu Ile Val Leu Arg Arg Asp Ile Leu His Arg Arg Ala
                 515                 520                 525

 Leu Glu Ala Lys Asp Ile Phe Ala Val Glu Tyr Gly Ile Pro Lys
                 530                 535                 540

 His Phe Gly Leu Phe Tyr Ala Met Gly Ile Ala Leu Met Met Glu
                 545                 550                 555

 Gly Val Leu Ser Ala Cys Tyr His Val Cys Pro Asn Tyr Ser Asn
                 560                 565                 570

 Phe Arg Phe Asp Thr Ser Phe Met Tyr Met Ile Ala Gly Leu Cys
                 575                 580                 585

 Met Leu Lys Leu Tyr Gln Thr Arg His Pro Asp Ile Asn Ala Ser
                 590                 595                 600

 Ala Tyr Ser Ala Tyr Ala Ser Phe Ala Val Val Ile Met Val Thr
                 605                 610                 615

 Val Leu Gly Val Val Phe Gly Lys Asn Asp Val Trp Phe Trp Val
                 620                 625                 630

 Ile Phe Ser Ala Ile His Val Leu Ala Ser Leu Ala Leu Ser Thr
                 635                 640                 645

 Gln Ile Tyr Tyr Met Gly Arg Phe Lys Ile Asp Leu Gly Ile Phe
                 650                 655                 660

 Arg Arg Ala Ala Met Val Phe Tyr Thr Asp Cys Ile Gln Gln Cys
                 665                 670                 675

 Ser Arg Pro Leu Tyr Met Asp Arg Met Val Leu Leu Val Val Gly
                 680                 685                 690

 Asn Leu Val Asn Trp Ser Phe Ala Leu Phe Gly Leu Ile Tyr Arg
                 695                 700                 705

 Pro Arg Asp Phe Ala Ser Tyr Met Leu Gly Ile Phe Ile Cys Asn
                 710                 715                 720

 Leu Leu Leu Tyr Leu Ala Phe Tyr Ile Ile Met Lys Leu Arg Ser
                 725                 730                 735

 Ser Glu Lys Val Leu Pro Val Pro Leu Phe Cys Ile Val Ala Thr
                 740                 745                 750

 Ala Val Met Trp Ala Ala Ala Leu Tyr Phe Phe Phe Gln Asn Leu
                 755                 760                 765

 Ser Ser Trp Glu Gly Thr Pro Ala Glu Ser Arg Glu Lys Asn Arg
                 770                 775                 780

 Glu Cys Ile Leu Leu Asp Phe Phe Asp Asp His Asp Ile Trp His
                 785                 790                 795

 Phe Leu Ser Ala Thr Ala Leu Phe Phe Ser Phe Leu Val Leu Leu
                 800                 805                 810

 Thr Leu Asp Asp Asp Leu Asp Val Val Arg Arg Asp Gln Ile Pro
                 815                 820                 825

 Val Phe


<210> 3459
<211> 2091
<212> DNA
<213> Homo sapien

<400> 3459
 gtacattttg aggaagcagc aactgctaag gagagatcaa aggtagctaa 50

 aattggtgct ttctgctgtg gccttagttt atgtaaccag cacacaataa 100

 tactctatgt tttgtgcata ataccttgga ttctctttca acttttaaaa 150

 aagaaggaac tctccctggg ctctttgttg aagttgagcc tgtacttctc 200

 tgctggtttg ctgccctatg tccaccttcc catctcatct taccttaatc 250

 acgcccggtg gacctgggga gaccagacaa cactgcaagg atttttgaca 300

 cattttctca gggaagaata tggaaccttc agcctggcca aatctgaaat 350

 aggatccagt atgtctgaaa tactgctttc tcaagtaaca aatatgagga 400

 ccgaactctc attcaacatc caagcccttg cagtttgtgc aaatatatgt 450

 ttagcaacaa aggacagaca gaatccatca ttagtatggc tttttactgg 500

 aatgttttgc atttattcat tggtctttgc ttggagagca aatttagata 550

 tttcaaaacc acttttcatg ggtgtggtgg aacgattctg gatgcagagc 600

 aatgcagtag tggccgtcct cgctggcatt ggtttggctg cagttgtgtc 650

 tgagactaac cgagtgctga atagcaatgg gcttcagtgt ctggaatggc 700

 tttctgcaac tctttttgta gtttaccaaa tatattctaa ttacagtgtt 750

 tgtgaccaaa ggaccaacta tgtgattgat aagttcgcaa agaaccttct 800

 cacctctatg cctcatgatg caattatctt actcagagga gatttgccag 850

 gaaattctct ccgttacatg cattactgtg aggggttgag gcctgacatt 900

 tcattagtgg atcaggaaat gatgacttac gagtggtatt tacccaagat 950

 ggcaaagcac ttgccaggtg tcaactttcc tgggaaccgg tggaatcctg 1000

 tggaaggaat attacctagt ggaatggtca catttaatct ttatcatttt 1050

 cttgaagtaa ataaacaaaa agaaacattt gtttgcatag gaattcatga 1100

 aggcgaccca acctggaaaa agaactattc actttggcca tgggggtctt 1150

 gtgacaaatt agttcctttg gagattgtat tcaaccctga ggaatggatt 1200

 aaacttacaa aaagtatcta taactggacc gaagaatatg gaaggtttga 1250

 tccatcttct tgggaatctg tggccaatga agaaatgtgg caagcgagga 1300

 tgaaaacacc gttcttcatc tttaacctgg cagaaactgc tcacatgcct 1350

 tcaaaagtga aagctcaact ctacgctcaa gcatatgacc tttataagga 1400

 gattgtctat ttacaaaagg agcacccagt gaattggcac aagaactatg 1450

 ccatcgcctg tgagcggatg ctgcgtcttc aggcaagaga tgcagatcct 1500

 gaagtgctgt tatcggaaac catcagacat ttccgtctgt actctcagaa 1550

 agcaccgaat gacccacagc aagctgatat tttaggtgct ctaaagcacc 1600

 taagaaaaga actgcaaagt ctgagaaata ggaaaaatgt ctgagacagc 1650

 aaaatatgaa aaacctgctc atcgttcagc ttccaaaatt ctgaagtctg 1700

 gaagtttttc cttcaagaaa agaaactgca taaaaaattt aaaactaagt 1750

 catctcccag atataagtat catggtccag cagtactgtt taatggggta 1800

 ttcagtgact aaggtctgct atttatgcaa aattctgttt atcccgtgtt 1850

 accaaattac catttcagtg agaagctttt gaaaagtctt ctgacttcca 1900

 gtctttcacc agatgactgc actggattag attccagaag agaatgaacc 1950

 attttcatat aactaaatat tggtcatgaa ctgtgtaagg gccatgctta 2000

 ttgggatcag ttttaaagtt aaattctttt gatattaata ccagaccaaa 2050

 gacattttct gtttcctgga aaaaaaaaaa aaaaaaaaaa a 2091

<210> 3460
<211> 427
<212> PRT
<213> Homo sapien

<400> 3460
 Met Ser Glu Ile Leu Leu Ser Gln Val Thr Asn Met Arg Thr Glu
   1               5                  10                  15

 Leu Ser Phe Asn Ile Gln Ala Leu Ala Val Cys Ala Asn Ile Cys
                  20                  25                  30

 Leu Ala Thr Lys Asp Arg Gln Asn Pro Ser Leu Val Trp Leu Phe
                  35                  40                  45

 Thr Gly Met Phe Cys Ile Tyr Ser Leu Val Phe Ala Trp Arg Ala
                  50                  55                  60

 Asn Leu Asp Ile Ser Lys Pro Leu Phe Met Gly Val Val Glu Arg
                  65                  70                  75

 Phe Trp Met Gln Ser Asn Ala Val Val Ala Val Leu Ala Gly Ile
                  80                  85                  90

 Gly Leu Ala Ala Val Val Ser Glu Thr Asn Arg Val Leu Asn Ser
                  95                 100                 105

 Asn Gly Leu Gln Cys Leu Glu Trp Leu Ser Ala Thr Leu Phe Val
                 110                 115                 120

 Val Tyr Gln Ile Tyr Ser Asn Tyr Ser Val Cys Asp Gln Arg Thr
                 125                 130                 135

 Asn Tyr Val Ile Asp Lys Phe Ala Lys Asn Leu Leu Thr Ser Met
                 140                 145                 150

 Pro His Asp Ala Ile Ile Leu Leu Arg Gly Asp Leu Pro Gly Asn
                 155                 160                 165

 Ser Leu Arg Tyr Met His Tyr Cys Glu Gly Leu Arg Pro Asp Ile
                 170                 175                 180

 Ser Leu Val Asp Gln Glu Met Met Thr Tyr Glu Trp Tyr Leu Pro
                 185                 190                 195

 Lys Met Ala Lys His Leu Pro Gly Val Asn Phe Pro Gly Asn Arg
                 200                 205                 210

 Trp Asn Pro Val Glu Gly Ile Leu Pro Ser Gly Met Val Thr Phe
                 215                 220                 225

 Asn Leu Tyr His Phe Leu Glu Val Asn Lys Gln Lys Glu Thr Phe
                 230                 235                 240

 Val Cys Ile Gly Ile His Glu Gly Asp Pro Thr Trp Lys Lys Asn
                 245                 250                 255

 Tyr Ser Leu Trp Pro Trp Gly Ser Cys Asp Lys Leu Val Pro Leu
                 260                 265                 270

 Glu Ile Val Phe Asn Pro Glu Glu Trp Ile Lys Leu Thr Lys Ser
                 275                 280                 285

 Ile Tyr Asn Trp Thr Glu Glu Tyr Gly Arg Phe Asp Pro Ser Ser
                 290                 295                 300

 Trp Glu Ser Val Ala Asn Glu Glu Met Trp Gln Ala Arg Met Lys
                 305                 310                 315

 Thr Pro Phe Phe Ile Phe Asn Leu Ala Glu Thr Ala His Met Pro
                 320                 325                 330

 Ser Lys Val Lys Ala Gln Leu Tyr Ala Gln Ala Tyr Asp Leu Tyr
                 335                 340                 345

 Lys Glu Ile Val Tyr Leu Gln Lys Glu His Pro Val Asn Trp His
                 350                 355                 360

 Lys Asn Tyr Ala Ile Ala Cys Glu Arg Met Leu Arg Leu Gln Ala
                 365                 370                 375

 Arg Asp Ala Asp Pro Glu Val Leu Leu Ser Glu Thr Ile Arg His
                 380                 385                 390

 Phe Arg Leu Tyr Ser Gln Lys Ala Pro Asn Asp Pro Gln Gln Ala
                 395                 400                 405

 Asp Ile Leu Gly Ala Leu Lys His Leu Arg Lys Glu Leu Gln Ser
                 410                 415                 420

 Leu Arg Asn Arg Lys Asn Val
                 425

<210> 3461
<211> 2170
<212> DNA
<213> Homo sapien

<400> 3461
 tcattttacc tctcttggtc atcagaaaat aatgaaaaga ggcaagaaat 50

 cgtatgaagg taagaatttt gagaacatct ttactctgag ctcatcgctt 100

 aatgaaaacc agagaaatct ccctggagag aaacaatata gatgtactga 150

 atgtggcaaa tgcttcaaac ggaactcttc tcttgttttg catcaccgaa 200

 ctcacaccgg agagaagcct tatacttgta atgagtgtgg aaagtccttc 250

 tccaagaact acaacctgat tgtgcatcaa agaatccaca caggagagaa 300

 gccctatgaa tgcagtaaat gtgggaaagc tttcagtgat ggctcagctc 350

 tgacacagca ccagagaatt cacacaggcg agaaacctta tgaatgccta 400

 gagtgtggaa aaaccttcaa ccgaaattca tccttaattt tgcaccaaag 450

 aactcataca ggggaaaaac catatagatg taacgaatgt gggaaaccct 500

 tcactgacat ctcccacctt acagtgcatc tcagaatcca caccggtgag 550

 aagccctatg agtgtagcaa atgtggaaag gctttccggg acggctcgta 600

 cctcacccag catgagagga ctcacactgg agaaaagccc tttgagtgtg 650

 cagagtgcgg gaaatccttc aacagaaact ctcacctcat tgtgcatcaa 700

 aagatccatt ctggggagaa accctatgaa tgtaaagaat gtggcaagac 750

 tttcatcgag agtgcgtacc tcatcaggca tcagaggatt catactggcg 800

 agaagcccta tggctgcaac cagtgtcaga aacttttcag gaatatcgct 850

 ggcctcatta ggcaccagag gactcatact ggtgagaagc cctatgagtg 900

 taatcagtgt ggcaaagcct tcagggacag ctcctgtctg accaagcacc 950

 agagaattca cactaaggag accccatatc agtgtccaga atgtgggaag 1000

 tccttcaagc agaactctca cctggcagta catcagagac tccatagcag 1050

 ggagggtccc agccggtgtc ctcagtgtgg aaaaatgttc caaaagagct 1100

 catcccttgt tcgacatcaa agagcacacc tgggagagca acccatggaa 1150

 acataatggt tgggggccac atgagtcttc cagttcactc tcactcctgt 1200

 gtttaggagg cgtgtcttag atctgactcc tctctggtca gtagaaaaga 1250

 atcctttaag ctatccagtg aattgatgaa tgtgagacat tgctgagcca 1300

 cactgttaag tctgctcatt ggggaactcc agagacaact taggatgagg 1350

 gcagaaaagt ctttggggat gattcagtct gtaccagaca tgacaacaca 1400

 cacactggaa tgaaatgtgc aaacatgggg gtgacaccac agagagaacc 1450

 tgtgaatgca ttcagaacat gattggaatg aagagccctg tagtagggag 1500

 tttccacctt gtacgtaagc aaacactgaa tcaacttttt tttttttttc 1550

 ggacagagtc tcactgtgca gtggcatgat ctccactcac agcaacctct 1600

 gcctcccagg ttcaagcagt tctcctgcct cagcctggcc agcatggtga 1650

 aaccccatct ctaccaaaaa tacaggaaat tatctgggca tagtagtgtg 1700

 tgcctgtaat cccagctact tgggaagctg aggcaggaga attgcttgaa 1750

 cctgggaggt ggaggttgca gtgagctaag atcgcaccac tgcactccag 1800

 cctgggtgac agagcgagac tccatttcaa aaaaaaagac tgaaacaagc 1850

 ttgtgctaag atggaaaggg ctgcttctaa cagatgtggt ttgttgcttt 1900

 agttgttgaa gcaaaaatac tgagttgtta tgtttatgtt atcaccccac 1950

 cactacctcc atggttgttc atttaggatg cttctaattc agccactgtg 2000

 aaccattata aaggttttat tgccatgttg aaaatgttta taatatggca 2050

 aaaaggggca tcaaatagaa gatttactat tattccagcc atgtaaaaat 2100

 atgtgcacat atggatgtat gttgaaagtg gatgatggag aaataaaatg 2150

 tggttttctt tggggactgg 2170

<210> 3462
<211> 374
<212> PRT
<213> Homo sapien

<400> 3462
 Met Lys Arg Gly Lys Lys Ser Tyr Glu Gly Lys Asn Phe Glu Asn
   1               5                  10                  15

 Ile Phe Thr Leu Ser Ser Ser Leu Asn Glu Asn Gln Arg Asn Leu
                  20                  25                  30

 Pro Gly Glu Lys Gln Tyr Arg Cys Thr Glu Cys Gly Lys Cys Phe
                  35                  40                  45

 Lys Arg Asn Ser Ser Leu Val Leu His His Arg Thr His Thr Gly
                  50                  55                  60

 Glu Lys Pro Tyr Thr Cys Asn Glu Cys Gly Lys Ser Phe Ser Lys
                  65                  70                  75

 Asn Tyr Asn Leu Ile Val His Gln Arg Ile His Thr Gly Glu Lys
                  80                  85                  90

 Pro Tyr Glu Cys Ser Lys Cys Gly Lys Ala Phe Ser Asp Gly Ser
                  95                 100                 105

 Ala Leu Thr Gln His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr
                 110                 115                 120

 Glu Cys Leu Glu Cys Gly Lys Thr Phe Asn Arg Asn Ser Ser Leu
                 125                 130                 135

 Ile Leu His Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Arg Cys
                 140                 145                 150

 Asn Glu Cys Gly Lys Pro Phe Thr Asp Ile Ser His Leu Thr Val
                 155                 160                 165

 His Leu Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Ser Lys
                 170                 175                 180

 Cys Gly Lys Ala Phe Arg Asp Gly Ser Tyr Leu Thr Gln His Glu
                 185                 190                 195

 Arg Thr His Thr Gly Glu Lys Pro Phe Glu Cys Ala Glu Cys Gly
                 200                 205                 210

 Lys Ser Phe Asn Arg Asn Ser His Leu Ile Val His Gln Lys Ile
                 215                 220                 225

 His Ser Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Thr
                 230                 235                 240

 Phe Ile Glu Ser Ala Tyr Leu Ile Arg His Gln Arg Ile His Thr
                 245                 250                 255

 Gly Glu Lys Pro Tyr Gly Cys Asn Gln Cys Gln Lys Leu Phe Arg
                 260                 265                 270

 Asn Ile Ala Gly Leu Ile Arg His Gln Arg Thr His Thr Gly Glu
                 275                 280                 285

 Lys Pro Tyr Glu Cys Asn Gln Cys Gly Lys Ala Phe Arg Asp Ser
                 290                 295                 300

 Ser Cys Leu Thr Lys His Gln Arg Ile His Thr Lys Glu Thr Pro
                 305                 310                 315

 Tyr Gln Cys Pro Glu Cys Gly Lys Ser Phe Lys Gln Asn Ser His
                 320                 325                 330

 Leu Ala Val His Gln Arg Leu His Ser Arg Glu Gly Pro Ser Arg
                 335                 340                 345

 Cys Pro Gln Cys Gly Lys Met Phe Gln Lys Ser Ser Ser Leu Val
                 350                 355                 360

 Arg His Gln Arg Ala His Leu Gly Glu Gln Pro Met Glu Thr
                 365                 370

<210> 3463
<211> 2428
<212> DNA
<213> Homo sapien

<400> 3463
 gaaaacattt tgctgaaaat ataagcaaac atcggccttg tcctccttgt 50

 gttcatacac tgtggaagct tttctctgcc tcctccgtga gagtgcgtgg 100

 ccgggagacc agaaacgtgg tcctttctct tgcctgtgag ctggtgcaga 150

 gatggaggaa gaagaatatg aacaaattcc ccaggagaat cccccagaag 200

 agctgtccca ggatcctgtg ctggagctgt caggaggtct aagggagaaa 250

 gaacagaaga ccccaaggag actgaggctc attctcatgg ggaaaacagg 300

 gagtgggaag agtgcaacag gaaacagcat cctcggcagg gacgtcttcg 350

 agtctaaact cagcaccaga cccgtgacca agacctccca gagacggagc 400

 cgagagtggg ctgggaagga gcttgaggtg attgacacac ccaacattct 450

 gtccccccag gtctcgccag aggtggcaga cgctatctgc caagccatcg 500

 tcttatccgc cccagggccc cacgccgtgc tcctggtgac acaactgggc 550

 cggttcacgg atgaggatca gcaggtggtc aggcgcctgc aggaggtctt 600

 tggagtgggg gttctgggtc acaccatcct ggtgttcacc cggaaggaag 650

 acctggctgg cagctccctg gaagactatg tgcgagagac caacaaccag 700

 gcccttgcct ggctggatgt gacccttgca cggcgccatt gcggcttcaa 750

 caacagggca cagggggagg agcaggaggc ccaactgcga gagctcatgg 800

 agaaagttga agccattatg tgggaaaacg aaggagatta ttacagcaac 850

 aaggcttacc aatataccca gcaaaacttt cggctgaaag aactacagga 900

 aaggcaagta agccagggcc aaggctctga ggacgtgcct ggtgaggagt 950

 cttggctgga aggactgtcc cagatccaga aggaatctga ggaagcccac 1000

 agatgcctgc tggggaaggc tgacctttga gcctgtgctg gacttgagcc 1050

 aaggacacca tcagcctttg cacccccctg tgtccagccc tctgtttctc 1100

 tttccatccc atggagtgct tcccagtctc caggtcatga cgtctggtgt 1150

 aggaagaggg gcatggggct tgaggacagg gtccagcatg cccagatcac 1200

 attccagttc cttcattcct tcttccagaa catctgggtc ctccctcctc 1250

 tgtgccccaa cagcacgctg tcttcctatt ggaccttcta tctcattggc 1300

 attgcctttc atgagttact tgtctatact ctgatagaac caaagtttct 1350

 tgagggcagg cctgtatctt ttacttctgt gtaacttcca cagcttttga 1400

 ctgcattgga gtcatgcagt cacgtttggt gcggcaactc catgcaagct 1450

 gttgaccaga tgacttctca tctctcccca caccatgatg gtttaaggtg 1500

 cctgttgtgt ctggtggaga cagtgctggg agatgatcag aaatctcagg 1550

 gcacagcctc aggtctacct ggacactcat ccactgttgg agatgctcaa 1600

 cagctagaca cagatgctca cagccgacct gtggcctctt gctctgaagc 1650

 catcccccat cttccctaga cacagcagac atctgagaaa gcttcagcat 1700

 ttctcttgct aacagattca gaaaagtgtc tcaaagcaga gcacagagtt 1750

 atttggtgtt tgctgaagac agcctttgtg ccacaatcac ttattaaata 1800

 agcgatcaat ttcccattga actgaacatg caacatttat catacattca 1850

 gttctcattc acactcctta agatttggtc agaattttta tttctgttca 1900

 tgtcttctac ttttctactc ctgtatgaat aaaatattga tttgattaca 1950

 gtggctttga ctataatgtg ggagccaatt tttgcctcag tcttcatttt 2000

 tatatttacc ttgttattct caggcatttt tttcttctat gtgagagtta 2050

 aaatcattct gtaatttccc cccaaaatca tattggtatt ctagttggca 2100

 atgtcttaca tttatgttaa gtttgaggga attggtagtt caagtataag 2150

 ttaattaagg ccattttatt tctaagtgaa cagacttgaa actccagagc 2200

 tactgaagta aaagttagaa tcatttgcat tttcattcag ataggagata 2250

 attttgtaaa ttttgatgct attattttaa ctctattagc ttaagtaatg 2300

 tcataataga aaacacaagc atttgaccaa atgagatcca ttcagcgact 2350

 aactggcaag gcactcaaaa catgtcattc attaaatgtt gtttttattt 2400

 acctcaaaaa aaaaaaaaaa aaaaaaaa 2428

<210> 3464
<211> 292
<212> PRT
<213> Homo sapien

<400> 3464
 Met Glu Glu Glu Glu Tyr Glu Gln Ile Pro Gln Glu Asn Pro Pro
   1               5                  10                  15

 Glu Glu Leu Ser Gln Asp Pro Val Leu Glu Leu Ser Gly Gly Leu
                  20                  25                  30

 Arg Glu Lys Glu Gln Lys Thr Pro Arg Arg Leu Arg Leu Ile Leu
                  35                  40                  45

 Met Gly Lys Thr Gly Ser Gly Lys Ser Ala Thr Gly Asn Ser Ile
                  50                  55                  60

 Leu Gly Arg Asp Val Phe Glu Ser Lys Leu Ser Thr Arg Pro Val
                  65                  70                  75

 Thr Lys Thr Ser Gln Arg Arg Ser Arg Glu Trp Ala Gly Lys Glu
                  80                  85                  90

 Leu Glu Val Ile Asp Thr Pro Asn Ile Leu Ser Pro Gln Val Ser
                  95                 100                 105

 Pro Glu Val Ala Asp Ala Ile Cys Gln Ala Ile Val Leu Ser Ala
                 110                 115                 120

 Pro Gly Pro His Ala Val Leu Leu Val Thr Gln Leu Gly Arg Phe
                 125                 130                 135

 Thr Asp Glu Asp Gln Gln Val Val Arg Arg Leu Gln Glu Val Phe
                 140                 145                 150

 Gly Val Gly Val Leu Gly His Thr Ile Leu Val Phe Thr Arg Lys
                 155                 160                 165

 Glu Asp Leu Ala Gly Ser Ser Leu Glu Asp Tyr Val Arg Glu Thr
                 170                 175                 180

 Asn Asn Gln Ala Leu Ala Trp Leu Asp Val Thr Leu Ala Arg Arg
                 185                 190                 195

 His Cys Gly Phe Asn Asn Arg Ala Gln Gly Glu Glu Gln Glu Ala
                 200                 205                 210

 Gln Leu Arg Glu Leu Met Glu Lys Val Glu Ala Ile Met Trp Glu
                 215                 220                 225

 Asn Glu Gly Asp Tyr Tyr Ser Asn Lys Ala Tyr Gln Tyr Thr Gln
                 230                 235                 240

 Gln Asn Phe Arg Leu Lys Glu Leu Gln Glu Arg Gln Val Ser Gln
                 245                 250                 255

 Gly Gln Gly Ser Glu Asp Val Pro Gly Glu Glu Ser Trp Leu Glu
                 260                 265                 270

 Gly Leu Ser Gln Ile Gln Lys Glu Ser Glu Glu Ala His Arg Cys
                 275                 280                 285

 Leu Leu Gly Lys Ala Asp Leu
                 290

<210> 3465
<211> 3916
<212> DNA
<213> Homo sapien

<400> 3465
 agagtgctga tttagaagaa tacaaatcat ggctgaaaat agtgtattaa 50

 catccactac tgggaggact agcttggcag actcttccat ttttgattct 100

 aaagttactg agatttccaa ggaaaactta cttattggat ctacttcata 150

 tgtagaagaa gagatgcctc agattgaaac aagagtgata ttggttcaag 200

 aagctggaaa acaagaagaa cttataaaag ccttaaagga cattaaagtg 250

 ggctttgtaa agatggagtc agtggaagaa tttgaaggtt tggattctcc 300

 ggaatttgaa aatgtatttg tagtcacgga ctttcaggat tctgtcttta 350

 atgacctcta caaggctgat tgtagagtta ttggaccacc agttgtatta 400

 aattgttcac aaaaaggaga gcctttgcca ttttcatgtc gcccgttgta 450

 ttgtacaagt atgatgaatc tagtactatg ctttactgga tttaggaaaa 500

 aagaagaact agtcaggttg gtgacattgg tccatcacat gggtggagtt 550

 attcgaaaag actttaattc aaaagttaca catttggtgg caaattgtac 600

 acaaggagaa aaattcaggg ttgctgtgag tctaggtact ccaattatga 650

 agccagaatg gatttataaa gcttgggaaa ggcggaatga acaggatttc 700

 tatgcagcag ttgatgactt tagaaatgaa tttaaagttc ctccatttca 750

 agattgtatt ttaagtttcc tgggattttc agatgaagag aaaaccaata 800

 tggaagaaat gactgaaatg caaggaggta aatatttacc gcttggagat 850

 gaaagatgca ctcaccttgt agttgaagag aatatagtaa aagatcttcc 900

 ctttgaacct tcaaagaaac tttatgttgt caagcaagag tggttctggg 950

 gaagcattca aatggatgcc cgagctggag aaactatgta tttatatgaa 1000

 aaggcaaata ctcctgagct caagaaatca gtgtcaatgc tttctctaaa 1050

 tacccctaac agcaatcgca aacgacgtcg tttaaaagaa acacttgctc 1100

 agctttcaag agagacagac gtgtcaccat ttccaccccg taagcgccca 1150

 tcagctgagc attccctttc catagggtca ctcctagata tctccaacac 1200

 accagagtct agcattaact atggagacac cccaaagtct tgtactaagt 1250

 cttctaaaag ctccactcca gttccttcaa agcagtcagc aaggtggcaa 1300

 gttgcaaaag agctttatca aactgaaagt aattatgtta atatattggc 1350

 aacaattatt cagttatttc aagtaccatt ggaagaggaa ggacaacgtg 1400

 gtggacctat ccttgcacca gaggagatta agactatttt tggtagcatc 1450

 ccagatatct ttgatgtaca cactaagata aaggatgatc ttgaagacct 1500

 tatagttaat tgggatgaga gcaaaagcat tggtgacatt tttctgaaat 1550

 attcaaaaga tttggtaaaa acctaccctc cctttgtaaa cttctttgaa 1600

 atgagcaagg aaacaattat taaatgtgaa aaacagaaac caagatttca 1650

 tgcttttctc aagataaacc aagcaaaacc agaatgtgga cggcagagcc 1700

 ttgttgaact tcttatccga ccagtacaga ggttacccag tgttgcatta 1750

 cttttaaatg atcttaagaa gcatacagct gatgaaaatc cagacaaaag 1800

 cactttagaa aaagctattg gatcactgaa ggaagtaatg acgcatatta 1850

 atgaggataa gagaaaaaca gaagctcaaa agcaaatttt tgatgttgtt 1900

 tatgaagtag atggatgccc agctaatctt ttatcttctc accgaagctt 1950

 agtacagcgg gttgaaacaa tttctctagg tgagcacccc tgtgacagag 2000

 gagaacaagt aactctcttc ctcttcaatg attgcctaga gatagcaaga 2050

 aaacggcaca aggttattgg cacttttagg agtcctcatg gccaaacccg 2100

 acccccagct tctcttaagc atattcacct aatgcctctt tctcagatta 2150

 agaaggtatt ggacataaga gagacagaag attgccataa tgcttttgcc 2200

 ttgcttgtga ggccaccaac agagcaggca aatgtgctac tcagtttcca 2250

 gatgacatca gatgaacttc caaaagaaaa ctggctaaag atgctgtgtc 2300

 gacatgtagc taacaccatt tgtaaagcag atgctgagaa tcttatttat 2350

 actgctgatc cagaatcctt tgaagtaaat acaaaagata tggacagtac 2400

 attgagtaga gcatcaagag caataaaaaa gacttcaaaa aaggttacaa 2450

 gagcattctc tttctccaaa actccaaaaa gagctcttcg aagggctctt 2500

 atgacatccc acggctcagt ggagggaaga agtccttcca gcaatgataa 2550

 gcatgtaatg agtcgtcttt ctagcacatc atcattagca ggtatccctt 2600

 ctccctccct tgtcagcctt ccttccttct ttgaaaggag aagtcatacg 2650

 ttaagtagat ctacaactca tttgatatga agcgttacca aaatcttaaa 2700

 ttatagaaat gtatagacac ctcatactca aataagaaac tgacttaaat 2750

 ggtacttgta attagcactt ggtgaaagct ggaaggaaga taaataacac 2800

 taaactatgc tatttgattt ttcttcttga aagagtaagg tttacctgtt 2850

 acattttcaa gttaattcat gtaaaaaatg atagtgattt tgatgtaatt 2900

 tatctcttgt ttgaatctgt cattcaaagg ccaataattt aagttgctat 2950

 cagctgatat tagtagcttt gcaaccctga tagagtaaat aaattttatg 3000

 ggcgggtgcc aaatactgct gtgaatctat ttgtatagta tccatgaatg 3050

 aatttatgga aatagatatt tgtgcagctc aatttatgca gagattaaat 3100

 gacatcataa tactggatga aaacttgcat agaattctga ttaaatagtg 3150

 ggtctgtttc acatgtgcag tttgaagtat ttaaataacc actcctttca 3200

 cagtttattt tcttctcaag cgttttcaag atctagcatg tggattttaa 3250

 aagatttgcc ctcattaaca agaataacat ttaaaggaga ttgtttcaaa 3300

 atatttttgc aaattgagat aaggacagaa agattgagaa acattgtata 3350

 ttttgcaaaa acaagatgtt tgtagctgtt tcagagagag tacggtatat 3400

 ttatggtaat tttatccact agcaaatctt gatttagttt gatagtgtgt 3450

 ggaattttat tttgaaggat aagaccatgg gaaaattgtg gtaaagactg 3500

 tttgtaccct tcatgaaata attctgaagt tgccatcagt tttactaatc 3550

 ttctgtgaaa tgcatagata tgcgcatgtt caacttttta ttgtggtctt 3600

 ataattaaat gtaaaattga aaattcattt gctgtttcaa agtgtgatat 3650

 ctttcacaat agccttttta tagtcagtaa ttcagaataa tcaagttcat 3700

 atggataaat gcatttttat ttcctatttc tttagggagt gctacaaatg 3750

 tttgtcactt aaatttcaag tttctgtttt aatagttaac tgactataga 3800

 ttgttttcta tgccatgtat gtgccacttc tgagagtagt aaatgactct 3850

 ttgctacatt ttaaaagcaa ttgtattagt aagaactttg taaataaata 3900

 cctaaaaccc aagtgt 3916

<210> 3466
<211> 883
<212> PRT
<213> Homo sapien

<400> 3466
 Met Ala Glu Asn Ser Val Leu Thr Ser Thr Thr Gly Arg Thr Ser
   1               5                  10                  15

 Leu Ala Asp Ser Ser Ile Phe Asp Ser Lys Val Thr Glu Ile Ser
                  20                  25                  30

 Lys Glu Asn Leu Leu Ile Gly Ser Thr Ser Tyr Val Glu Glu Glu
                  35                  40                  45

 Met Pro Gln Ile Glu Thr Arg Val Ile Leu Val Gln Glu Ala Gly
                  50                  55                  60

 Lys Gln Glu Glu Leu Ile Lys Ala Leu Lys Asp Ile Lys Val Gly
                  65                  70                  75

 Phe Val Lys Met Glu Ser Val Glu Glu Phe Glu Gly Leu Asp Ser
                  80                  85                  90

 Pro Glu Phe Glu Asn Val Phe Val Val Thr Asp Phe Gln Asp Ser
                  95                 100                 105

 Val Phe Asn Asp Leu Tyr Lys Ala Asp Cys Arg Val Ile Gly Pro
                 110                 115                 120

 Pro Val Val Leu Asn Cys Ser Gln Lys Gly Glu Pro Leu Pro Phe
                 125                 130                 135

 Ser Cys Arg Pro Leu Tyr Cys Thr Ser Met Met Asn Leu Val Leu
                 140                 145                 150

 Cys Phe Thr Gly Phe Arg Lys Lys Glu Glu Leu Val Arg Leu Val
                 155                 160                 165

 Thr Leu Val His His Met Gly Gly Val Ile Arg Lys Asp Phe Asn
                 170                 175                 180

 Ser Lys Val Thr His Leu Val Ala Asn Cys Thr Gln Gly Glu Lys
                 185                 190                 195

 Phe Arg Val Ala Val Ser Leu Gly Thr Pro Ile Met Lys Pro Glu
                 200                 205                 210

 Trp Ile Tyr Lys Ala Trp Glu Arg Arg Asn Glu Gln Asp Phe Tyr
                 215                 220                 225

 Ala Ala Val Asp Asp Phe Arg Asn Glu Phe Lys Val Pro Pro Phe
                 230                 235                 240

 Gln Asp Cys Ile Leu Ser Phe Leu Gly Phe Ser Asp Glu Glu Lys
                 245                 250                 255

 Thr Asn Met Glu Glu Met Thr Glu Met Gln Gly Gly Lys Tyr Leu
                 260                 265                 270

 Pro Leu Gly Asp Glu Arg Cys Thr His Leu Val Val Glu Glu Asn
                 275                 280                 285

 Ile Val Lys Asp Leu Pro Phe Glu Pro Ser Lys Lys Leu Tyr Val
                 290                 295                 300

 Val Lys Gln Glu Trp Phe Trp Gly Ser Ile Gln Met Asp Ala Arg
                 305                 310                 315

 Ala Gly Glu Thr Met Tyr Leu Tyr Glu Lys Ala Asn Thr Pro Glu
                 320                 325                 330

 Leu Lys Lys Ser Val Ser Met Leu Ser Leu Asn Thr Pro Asn Ser
                 335                 340                 345

 Asn Arg Lys Arg Arg Arg Leu Lys Glu Thr Leu Ala Gln Leu Ser
                 350                 355                 360

 Arg Glu Thr Asp Val Ser Pro Phe Pro Pro Arg Lys Arg Pro Ser
                 365                 370                 375

 Ala Glu His Ser Leu Ser Ile Gly Ser Leu Leu Asp Ile Ser Asn
                 380                 385                 390

 Thr Pro Glu Ser Ser Ile Asn Tyr Gly Asp Thr Pro Lys Ser Cys
                 395                 400                 405

 Thr Lys Ser Ser Lys Ser Ser Thr Pro Val Pro Ser Lys Gln Ser
                 410                 415                 420

 Ala Arg Trp Gln Val Ala Lys Glu Leu Tyr Gln Thr Glu Ser Asn
                 425                 430                 435

 Tyr Val Asn Ile Leu Ala Thr Ile Ile Gln Leu Phe Gln Val Pro
                 440                 445                 450

 Leu Glu Glu Glu Gly Gln Arg Gly Gly Pro Ile Leu Ala Pro Glu
                 455                 460                 465

 Glu Ile Lys Thr Ile Phe Gly Ser Ile Pro Asp Ile Phe Asp Val
                 470                 475                 480

 His Thr Lys Ile Lys Asp Asp Leu Glu Asp Leu Ile Val Asn Trp
                 485                 490                 495

 Asp Glu Ser Lys Ser Ile Gly Asp Ile Phe Leu Lys Tyr Ser Lys
                 500                 505                 510

 Asp Leu Val Lys Thr Tyr Pro Pro Phe Val Asn Phe Phe Glu Met
                 515                 520                 525

 Ser Lys Glu Thr Ile Ile Lys Cys Glu Lys Gln Lys Pro Arg Phe
                 530                 535                 540

 His Ala Phe Leu Lys Ile Asn Gln Ala Lys Pro Glu Cys Gly Arg
                 545                 550                 555

 Gln Ser Leu Val Glu Leu Leu Ile Arg Pro Val Gln Arg Leu Pro
                 560                 565                 570

 Ser Val Ala Leu Leu Leu Asn Asp Leu Lys Lys His Thr Ala Asp
                 575                 580                 585

 Glu Asn Pro Asp Lys Ser Thr Leu Glu Lys Ala Ile Gly Ser Leu
                 590                 595                 600

 Lys Glu Val Met Thr His Ile Asn Glu Asp Lys Arg Lys Thr Glu
                 605                 610                 615

 Ala Gln Lys Gln Ile Phe Asp Val Val Tyr Glu Val Asp Gly Cys
                 620                 625                 630

 Pro Ala Asn Leu Leu Ser Ser His Arg Ser Leu Val Gln Arg Val
                 635                 640                 645

 Glu Thr Ile Ser Leu Gly Glu His Pro Cys Asp Arg Gly Glu Gln
                 650                 655                 660

 Val Thr Leu Phe Leu Phe Asn Asp Cys Leu Glu Ile Ala Arg Lys
                 665                 670                 675

 Arg His Lys Val Ile Gly Thr Phe Arg Ser Pro His Gly Gln Thr
                 680                 685                 690

 Arg Pro Pro Ala Ser Leu Lys His Ile His Leu Met Pro Leu Ser
                 695                 700                 705

 Gln Ile Lys Lys Val Leu Asp Ile Arg Glu Thr Glu Asp Cys His
                 710                 715                 720

 Asn Ala Phe Ala Leu Leu Val Arg Pro Pro Thr Glu Gln Ala Asn
                 725                 730                 735

 Val Leu Leu Ser Phe Gln Met Thr Ser Asp Glu Leu Pro Lys Glu
                 740                 745                 750

 Asn Trp Leu Lys Met Leu Cys Arg His Val Ala Asn Thr Ile Cys
                 755                 760                 765

 Lys Ala Asp Ala Glu Asn Leu Ile Tyr Thr Ala Asp Pro Glu Ser
                 770                 775                 780

 Phe Glu Val Asn Thr Lys Asp Met Asp Ser Thr Leu Ser Arg Ala
                 785                 790                 795

 Ser Arg Ala Ile Lys Lys Thr Ser Lys Lys Val Thr Arg Ala Phe
                 800                 805                 810

 Ser Phe Ser Lys Thr Pro Lys Arg Ala Leu Arg Arg Ala Leu Met
                 815                 820                 825

 Thr Ser His Gly Ser Val Glu Gly Arg Ser Pro Ser Ser Asn Asp
                 830                 835                 840

 Lys His Val Met Ser Arg Leu Ser Ser Thr Ser Ser Leu Ala Gly
                 845                 850                 855

 Ile Pro Ser Pro Ser Leu Val Ser Leu Pro Ser Phe Phe Glu Arg
                 860                 865                 870

 Arg Ser His Thr Leu Ser Arg Ser Thr Thr His Leu Ile
                 875                 880

<210> 3467
<211> 3141
<212> DNA
<213> Homo sapien

<400> 3467
 cgaaaagctg cggttaagga gagtccggtt taaccgtcac cgggaagcgc 50

 gctcgttcgg gatcgccgag ggggctgaga tagtgaattc ctaagaagaa 100

 aataatggat tgcatattag ttgttctcta agtggactca acagtgtgca 150

 agcttgttgg aaaagccaaa agaagatggc aactccttat gtcccagttc 200

 ctatgcccat aggaaactct gcttccagtt ttacaacaaa cagaaatcaa 250

 agaagttctt cttttggcag tgtctcaaca agctcaaatt cttctaaggg 300

 ccagttagaa gactcaaata tgggtaattt taaacagaca agtgttcctg 350

 atcaaatgga taatacttca tctgtctgta gcagtcccct cattaggact 400

 aaatttacag gtacagcttc ttccattgag tattctacta gaccaagaga 450

 cactgaagaa caaaatccgg aaacagtgaa ttgggaagat agaccatcta 500

 cacctactat actgggttat gaagtgatgg aagaaagagc taaatttact 550

 gtatataaaa tactagtaaa gaaaacccca gaagaaagct gggtagtttt 600

 cagaagatac actgacttct ctaggcttaa tgacaaatta aaagagatgt 650

 ttccaggttt tcgactagca cttcctccaa aacgctggtt taaagataat 700

 tacaatgctg actttttaga agacagacaa ttaggattac aagcgtttct 750

 tcaaaattta gtagctcaca aggacattgc taactgcctt gcagtgagag 800

 aatttctttg tttggatgat ccaccgggtc catttgatag cctagaggaa 850

 agcagggcat tctgtgaaac tttagaagag acaaactacc gcttacagaa 900

 agaactactt gaaaaacaaa aggagatgga atcactaaag aaactgctca 950

 gtgagaagca acttcatata gacactttag agaacagaat cagaacattg 1000

 tctttagaac ctgaagaatc actggatgtg tcagaaacag aaggtgaaca 1050

 gatcctaaag gtggagtcct ctgcacttga ggttgatcaa gatgtcctgg 1100

 atgaagaatc tagagctgat aataaaccat gcttaagttt tagtgaacct 1150

 gaaaatgctg tatcagagat agaagtagca gaagtggcat atgatgctga 1200

 agaagactaa tgtatcacaa gcagttccct ccatttagac tattcaaaaa 1250

 tttagaagag tggcaaatac tattttaaaa gaagaaccaa gaactgtaaa 1300

 acatatagaa aagagcaaga atgcacatgt ataaagttta cataaagaag 1350

 tttttttaag ttattgagat aggaaatata ttcactgctg cttttaattg 1400

 tattttatcc aattacattt aatacactaa aaaaaatctt gttggaattc 1450

 tgttatcaag gcccacattc ttaaatactg tgcataaatt attatggtgt 1500

 tttgcctata tattgctcca aactactgtg tatatatgta tgtgtgttaa 1550

 atcaccaatt atattaatca aatggaaatt aattgcatgt tactatctgg 1600

 gtgatatatt cttctttata tctctgacat gacatatttt cattaatagt 1650

 ttaaatcagt gaccatcata ataaagataa aatttagttg agtttttaat 1700

 gtttacatgt ttacatcttt aaataaaatt tgcttatttg aaatgttaat 1750

 gctctttaga aaaatgactt tctagtacca aaggaaaact acttgaaaga 1800

 gctgtaatca tatagctaaa gtgataagat agccttgatt ttaaaagctg 1850

 attcattaat atcaaaatac tttaataagt gtcacagtta ttaatatgtt 1900

 acatttgttt agtttccacg taatctttat ctctacctag atttagtgag 1950

 tttgcctctt tcagaatact acctcctttt gttaaggcat attctttcga 2000

 aaatatagat tctaaataaa taggggctta tacaaaaaag aaaataaaaa 2050

 gccatatata ctgcaaagtt cctaactggc ttgactcctg acattgcatt 2100

 tttatttcta tttgtgtgaa gatgttgtta tactgtatta tggctgattt 2150

 tctttttaat atatttagcc aagtgatgca ctttatgata attaaactct 2200

 tttgtgccaa gtttaattgg tggatttttt tagtaagtag agttaggaga 2250

 aagaattatg tagtgccttt actatttcac tttctacaaa agtctcctag 2300

 ggtctttgag tcagctttat gaaaaaatgt ttgtttattt cagctttgtg 2350

 tacagtcatt aaaagtgcct tgtttcattt ttataggatg aagttattta 2400

 ttttctattt tcactgtttt gcatattgct gttaataagc attgtaatca 2450

 tgctggcatt ttgcaatccc agtcggtatg ctttctaaaa actgagggaa 2500

 acttactggg gaaatagaat aacaatctcc atttttttct ttactatcta 2550

 aaagtttatc ggtatcttga tgtatatata tattaaggtg tggctgttta 2600

 aaattctaat gacatatatc aacacattca atggctgttg ttaacctttg 2650

 aagtaaaaag gagatcactt tttaccaaat aaccaaaaat ttttagtctt 2700

 tgtcaaagtg cacaggtatg ttctcagaac atttttcaca atgtgtatca 2750

 gaaatatgtt tgctatcctt agagacagaa atgaatataa caaattgatc 2800

 tgcttattta ttaaaattat tattctagac ttacaaaagg cttaaaaaga 2850

 acaatcattt aatcagtacc attctgtatc ttatataaca gatctttgcc 2900

 aaattctaga tattatagtg ttgcctgtct gttctaaagc gaaccagcca 2950

 ctttttcaat ctggcttttt ggaagattgt atttaaagtt cttcaaggat 3000

 gaagaaaaaa atctgttaat taggtaaacc actattattt atatttataa 3050

 tttacttttt tttactttta taatgcattt tactcccagt attatgttca 3100

 tttaataaat tattttttca ctacaaaaaa aaaaaaaaaa a 3141

<210> 3468
<211> 344
<212> PRT
<213> Homo sapien

<400> 3468
 Met Ala Thr Pro Tyr Val Pro Val Pro Met Pro Ile Gly Asn Ser
   1               5                  10                  15

 Ala Ser Ser Phe Thr Thr Asn Arg Asn Gln Arg Ser Ser Ser Phe
                  20                  25                  30

 Gly Ser Val Ser Thr Ser Ser Asn Ser Ser Lys Gly Gln Leu Glu
                  35                  40                  45

 Asp Ser Asn Met Gly Asn Phe Lys Gln Thr Ser Val Pro Asp Gln
                  50                  55                  60

 Met Asp Asn Thr Ser Ser Val Cys Ser Ser Pro Leu Ile Arg Thr
                  65                  70                  75

 Lys Phe Thr Gly Thr Ala Ser Ser Ile Glu Tyr Ser Thr Arg Pro
                  80                  85                  90

 Arg Asp Thr Glu Glu Gln Asn Pro Glu Thr Val Asn Trp Glu Asp
                  95                 100                 105

 Arg Pro Ser Thr Pro Thr Ile Leu Gly Tyr Glu Val Met Glu Glu
                 110                 115                 120

 Arg Ala Lys Phe Thr Val Tyr Lys Ile Leu Val Lys Lys Thr Pro
                 125                 130                 135

 Glu Glu Ser Trp Val Val Phe Arg Arg Tyr Thr Asp Phe Ser Arg
                 140                 145                 150

 Leu Asn Asp Lys Leu Lys Glu Met Phe Pro Gly Phe Arg Leu Ala
                 155                 160                 165

 Leu Pro Pro Lys Arg Trp Phe Lys Asp Asn Tyr Asn Ala Asp Phe
                 170                 175                 180

 Leu Glu Asp Arg Gln Leu Gly Leu Gln Ala Phe Leu Gln Asn Leu
                 185                 190                 195

 Val Ala His Lys Asp Ile Ala Asn Cys Leu Ala Val Arg Glu Phe
                 200                 205                 210

 Leu Cys Leu Asp Asp Pro Pro Gly Pro Phe Asp Ser Leu Glu Glu
                 215                 220                 225

 Ser Arg Ala Phe Cys Glu Thr Leu Glu Glu Thr Asn Tyr Arg Leu
                 230                 235                 240

 Gln Lys Glu Leu Leu Glu Lys Gln Lys Glu Met Glu Ser Leu Lys
                 245                 250                 255

 Lys Leu Leu Ser Glu Lys Gln Leu His Ile Asp Thr Leu Glu Asn
                 260                 265                 270

 Arg Ile Arg Thr Leu Ser Leu Glu Pro Glu Glu Ser Leu Asp Val
                 275                 280                 285

 Ser Glu Thr Glu Gly Glu Gln Ile Leu Lys Val Glu Ser Ser Ala
                 290                 295                 300

 Leu Glu Val Asp Gln Asp Val Leu Asp Glu Glu Ser Arg Ala Asp
                 305                 310                 315

 Asn Lys Pro Cys Leu Ser Phe Ser Glu Pro Glu Asn Ala Val Ser
                 320                 325                 330

 Glu Ile Glu Val Ala Glu Val Ala Tyr Asp Ala Glu Glu Asp
                 335                 340

<210> 3469
<211> 1279
<212> DNA
<213> Homo sapien

<400> 3469
 ggcacgaggg gaagtggctg tttggctgct gacaacatga agacttcctg 50

 cgatgagaac agaggcacag gtgccggccc tgcagccccc agaacctgga 100

 ctggaggggg ccatggggca ccggaccctg gtcctgccct gggtgctgct 150

 gaccttgtgt gtcactgcgg ggaccccgga ggtgtgggtt caagttcgga 200

 tggaggccac cgagctctcg tccttcacca tccgttgtgg gttcctgggg 250

 tctggctcca tctccctggt gactgtgagc tgggggggcc ccgacggtgc 300

 tggggggacc acgctggctg tgttgcaccc agaacgtggc atccggcaat 350

 gggcccctgc tcgccaggcc cgctgggaaa cccagagcag catctctctc 400

 atcctggaag gctctggggc cagcagcccc tgcgccaaca ccaccttctg 450

 ctgcaagttt gcgtccttcc ctgagggctc ctgggaggcc tgtgggagcc 500

 tcccgcccag ctcagaccca gggctctctg ccccgccgac tcctgccccc 550

 attctgcggg cagacctggc cgggatcttg ggggtctcag gagtcctcct 600

 ctttggctgt gtctacctcc ttcatctgct gcgccgacat aagcaccgcc 650

 ctgcccctag gctccagccg tcccgcacca gcccccaggc accgagagca 700

 cgagcatggg caccaagcca ggcctcccag gctgctcttc acgtccctta 750

 tgccactatc aacaccagct gccgcccagc tactttggac acagctcacc 800

 cccatggggg gccgtcctgg tgggcgtcac tccccaccca cgctgcacac 850

 cggccccagg gccctgccgc ctgggcctcc acacccatcc ctgcacgtgg 900

 cagctttgtc tctgttgaga atggactcta cgctcaggca ggggagaggc 950

 ctcctcacac tggtcccggc ctcactcttt tccctgaccc tcgggggccc 1000

 agggccatgg aaggaccctt aggagttcga tgagagagac catgaggcca 1050

 ctgggctttc cccctcccag gcctcctggg tgtcatcccc ttactttaat 1100

 tcttgggcct ccaataagtg tcccataggt gtctggccag gcccacctgc 1150

 tgcggatgtg gtctgtgtgc gtgtgtgggc acaggtgtga gtgtgtgagt 1200

 gacagttacc ccatttcagt catttcctgc tgcaactaag tcagcaacac 1250

 agtttctctg aaaaaaaaaa aaaaaaaaa 1279

<210> 3470
<211> 326
<212> PRT
<213> Homo sapien

<400> 3470
 Met Arg Thr Glu Ala Gln Val Pro Ala Leu Gln Pro Pro Glu Pro
   1               5                  10                  15

 Gly Leu Glu Gly Ala Met Gly His Arg Thr Leu Val Leu Pro Trp
                  20                  25                  30

 Val Leu Leu Thr Leu Cys Val Thr Ala Gly Thr Pro Glu Val Trp
                  35                  40                  45

 Val Gln Val Arg Met Glu Ala Thr Glu Leu Ser Ser Phe Thr Ile
                  50                  55                  60

 Arg Cys Gly Phe Leu Gly Ser Gly Ser Ile Ser Leu Val Thr Val
                  65                  70                  75

 Ser Trp Gly Gly Pro Asp Gly Ala Gly Gly Thr Thr Leu Ala Val
                  80                  85                  90

 Leu His Pro Glu Arg Gly Ile Arg Gln Trp Ala Pro Ala Arg Gln
                  95                 100                 105

 Ala Arg Trp Glu Thr Gln Ser Ser Ile Ser Leu Ile Leu Glu Gly
                 110                 115                 120

 Ser Gly Ala Ser Ser Pro Cys Ala Asn Thr Thr Phe Cys Cys Lys
                 125                 130                 135

 Phe Ala Ser Phe Pro Glu Gly Ser Trp Glu Ala Cys Gly Ser Leu
                 140                 145                 150

 Pro Pro Ser Ser Asp Pro Gly Leu Ser Ala Pro Pro Thr Pro Ala
                 155                 160                 165

 Pro Ile Leu Arg Ala Asp Leu Ala Gly Ile Leu Gly Val Ser Gly
                 170                 175                 180

 Val Leu Leu Phe Gly Cys Val Tyr Leu Leu His Leu Leu Arg Arg
                 185                 190                 195

 His Lys His Arg Pro Ala Pro Arg Leu Gln Pro Ser Arg Thr Ser
                 200                 205                 210

 Pro Gln Ala Pro Arg Ala Arg Ala Trp Ala Pro Ser Gln Ala Ser
                 215                 220                 225

 Gln Ala Ala Leu His Val Pro Tyr Ala Thr Ile Asn Thr Ser Cys
                 230                 235                 240

 Arg Pro Ala Thr Leu Asp Thr Ala His Pro His Gly Gly Pro Ser
                 245                 250                 255

 Trp Trp Ala Ser Leu Pro Thr His Ala Ala His Arg Pro Gln Gly
                 260                 265                 270

 Pro Ala Ala Trp Ala Ser Thr Pro Ile Pro Ala Arg Gly Ser Phe
                 275                 280                 285

 Val Ser Val Glu Asn Gly Leu Tyr Ala Gln Ala Gly Glu Arg Pro
                 290                 295                 300

 Pro His Thr Gly Pro Gly Leu Thr Leu Phe Pro Asp Pro Arg Gly
                 305                 310                 315

 Pro Arg Ala Met Glu Gly Pro Leu Gly Val Arg
                 320                 325

<210> 3471
<211> 3438
<212> DNA
<213> Homo sapien

<400> 3471
 gccgcggaga aggagccgga ccccttgggc ggagcgccca atgtgtggtc 50

 cctcacgccg tcccgcacct tgctttttag ggttcttttt ccgctttctg 100

 agccctttta taccttacgt ttagaagggg aaaatcatcc tcccacacct 150

 tctccccgac tttttgcctt ttttgtcttg aagttaccca aaggcctgtg 200

 tattgttctc aatggtccca agaattactc taatatagtt gtttttctga 250

 gggaggatgg atggagataa ctatcctgat cccaatgtca ctttttaagg 300

 cattcgcttc aagagacaag cagtttagaa tcaggcagaa ctggattgca 350

 aaatttatgg gcagaccgag aaaatgctgc tgtgaagacc caattaaagc 400

 tttcacataa atgaagctac agctatcatg atttagtgcc cccaaaagga 450

 agaacttcag tggacaagaa aggacatttc tgggggtagt agaatgcttg 500

 aggcctggaa tttaaacctg agccactatc tgaaggttta atatatcttt 550

 gccaagtcca agggtacaaa gattttctcc tgtgttttct tctagaagtt 600

 ttatcatttg atagtctgtg atccatttca agttgatttg ctatctggtg 650

 tgagctatta aataatagaa gaaaatggaa ttgaatatga tgtcagcatg 700

 gaacaatcta atgattcatt aagagtcaac cataatgacg gtgaagagtc 750

 aaaaaccagt gctcaagtat ttgagcatct aatctgtatg gactccaggg 800

 attcttcctt tggacaaaat gattctccta cagttttgcc catcactact 850

 cgtgaagcaa ataattcact catatcacag aatataccag ggcccctgac 900

 tcagacacag actctttctg cagagcaatt ccatctagtg gaccaaaatg 950

 ggcaggctat tcaatatgaa cttcagtcat tgggggaatc caatgcacaa 1000

 atgatgatcg ttgccagccc aacagaaaat ggacaggtac ttcgtgtaat 1050

 tccacctacc cagacaggaa tggcacaagt gattatacct caggggcaac 1100

 ttgtggatgt gaatagtcct cgggatgtcc ctgaagagaa acccagtaac 1150

 agaaacttac caactgtaag agtggatact ctagcagaca ataccagcaa 1200

 ttacattctt catcctcaaa catccttccc attgcccaaa aagtcagtga 1250

 ccggaatgct ggaagaaccc cttctggggc ctcttcagcc actttcttct 1300

 aatacaccta tatgggcctg ccgtcttagg agctgtgaga aaattggaga 1350

 ttcataccgt ggctactgtg taagtgagac tgaattagaa agtgtcctaa 1400

 catttcacaa gcagcaaaca cagagtgttt gggggacccg tcagtctcca 1450

 agcccagcca agcctgctac acgcttgatg tggaaatccc agtatgttcc 1500

 atatgatgga atcccatttg ttaatgcagg gagtagagct gtggtaatgg 1550

 agtgtcagta tgggccaaga agaaaaggtt tccagttaaa aaaagtcagt 1600

 gagcaggaaa gcaggtcttg tcagctctac aaagccactt gtccagctcg 1650

 gatttacatt aaaaaggtac agaagtttcc tgaatataga gttcctacag 1700

 accccaaaat tgacaagaaa attatcagaa tggagcagga gaaagctttt 1750

 aacatgctaa agaagaactt ggtagatgct ggtggtgttc ttaggtggta 1800

 tgtacagtta cctacacagc aagctcatca gtatcatgaa ttagagactc 1850

 cctgcctcac tttgtcacct tctccttttc ctgtgtcttc tcttgaagaa 1900

 gaggaaactg cagttagaga tgagaattgt gcattaccct cacgtttaca 1950

 tcctcaagta gcacataaga ttcaagaatt agtatcacag ggaatagaac 2000

 aagtgtatgc agtaaggaaa cagctaagaa aatttgtgga aagggaactg 2050

 ttcaaacccg atgaggtacc tgaaagacat aatttatctt tttttccaac 2100

 tgtaaatgat ataaaaaatc acatccatga ggtacagaaa tccttgagaa 2150

 atggagatac ggtatataac tcagagatta ttccagcaac gcttcaatgg 2200

 actacagaca gtgggaatat tctcaaagag accatgacag ttacatttgc 2250

 agaaggaaat tcaccaggag aatcaattac caccaaagtg gaaacaaatc 2300

 agaccagggg ttctttgtct cctgagccaa cccacttgct ctcctcactc 2350

 tcctcatttc agcccaaaat atttacacaa ctacagggtt tgcagttaca 2400

 accaaggtac acctctcctg atgaatcacc agctgtggta tcagtaaata 2450

 accagccgtc ctctagtcct tcaggacttc tggatacaat aggaagtgct 2500

 gtaatgaata ataattctct actgcttggt caaagtcata gccttcaaag 2550

 agatacatgc ttaacccaaa acaatagtac tgcctccacc atgggtaacc 2600

 ttccagaacc agatcaaaat ctagttgcaa tggacgagct ggtagaagtt 2650

 ggagatgttg aggatacagg gaatctggaa ggaactgttc atcggattct 2700

 gttgggagat gtgcagacta ttccaataca gattatagac aaccactcag 2750

 ctcttattga agaaaatcca gaaagtacca tttctgtgag ccaagttaaa 2800

 caagaaccca aagaaccagc attgtctatg gaagcaaaaa actgtggact 2850

 ataagaaatt atctgctaca taaattattg aagcttttca gaatttacaa 2900

 ctctggtgac ttctgatgtc ttagaaagga aggtgaatat agtcaaagcg 2950

 tggcattgag ataattggac tgaagaccag tttgatgaga agcttttatt 3000

 taaaactgat atatttgttg ccagttccat atttttacct tccttaagag 3050

 atgttttact cttcttattt tgtataattt ttatgctctt tgattatcta 3100

 ataaggccag tatttcaaaa gctgttctga atttatccac agtaatatag 3150

 tctgaacaca aatagtttac ttaacttatc cttggaaata ttcaattttg 3200

 gttattacaa aacagaaaag aacaacagca acaaaaacat tgtgtgaata 3250

 tatgtttgta tgtgtgtatg tatatcatga attttttttt taagttctga 3300

 aaaagaactt gttctctcct taaagttgtg aagaaattgt taattgccag 3350

 acaggtaaga aaatgtttat aatctatctc attaagaaag atgaagtatt 3400

 agattttaca tcataacaca aagtccagca gctacatc 3438

<210> 3472
<211> 718
<212> PRT
<213> Homo sapien

<400> 3472
 Met Glu Gln Ser Asn Asp Ser Leu Arg Val Asn His Asn Asp Gly
   1               5                  10                  15

 Glu Glu Ser Lys Thr Ser Ala Gln Val Phe Glu His Leu Ile Cys
                  20                  25                  30

 Met Asp Ser Arg Asp Ser Ser Phe Gly Gln Asn Asp Ser Pro Thr
                  35                  40                  45

 Val Leu Pro Ile Thr Thr Arg Glu Ala Asn Asn Ser Leu Ile Ser
                  50                  55                  60

 Gln Asn Ile Pro Gly Pro Leu Thr Gln Thr Gln Thr Leu Ser Ala
                  65                  70                  75

 Glu Gln Phe His Leu Val Asp Gln Asn Gly Gln Ala Ile Gln Tyr
                  80                  85                  90

 Glu Leu Gln Ser Leu Gly Glu Ser Asn Ala Gln Met Met Ile Val
                  95                 100                 105

 Ala Ser Pro Thr Glu Asn Gly Gln Val Leu Arg Val Ile Pro Pro
                 110                 115                 120

 Thr Gln Thr Gly Met Ala Gln Val Ile Ile Pro Gln Gly Gln Leu
                 125                 130                 135

 Val Asp Val Asn Ser Pro Arg Asp Val Pro Glu Glu Lys Pro Ser
                 140                 145                 150

 Asn Arg Asn Leu Pro Thr Val Arg Val Asp Thr Leu Ala Asp Asn
                 155                 160                 165

 Thr Ser Asn Tyr Ile Leu His Pro Gln Thr Ser Phe Pro Leu Pro
                 170                 175                 180

 Lys Lys Ser Val Thr Gly Met Leu Glu Glu Pro Leu Leu Gly Pro
                 185                 190                 195

 Leu Gln Pro Leu Ser Ser Asn Thr Pro Ile Trp Ala Cys Arg Leu
                 200                 205                 210

 Arg Ser Cys Glu Lys Ile Gly Asp Ser Tyr Arg Gly Tyr Cys Val
                 215                 220                 225

 Ser Glu Thr Glu Leu Glu Ser Val Leu Thr Phe His Lys Gln Gln
                 230                 235                 240

 Thr Gln Ser Val Trp Gly Thr Arg Gln Ser Pro Ser Pro Ala Lys
                 245                 250                 255

 Pro Ala Thr Arg Leu Met Trp Lys Ser Gln Tyr Val Pro Tyr Asp
                 260                 265                 270

 Gly Ile Pro Phe Val Asn Ala Gly Ser Arg Ala Val Val Met Glu
                 275                 280                 285

 Cys Gln Tyr Gly Pro Arg Arg Lys Gly Phe Gln Leu Lys Lys Val
                 290                 295                 300

 Ser Glu Gln Glu Ser Arg Ser Cys Gln Leu Tyr Lys Ala Thr Cys
                 305                 310                 315

 Pro Ala Arg Ile Tyr Ile Lys Lys Val Gln Lys Phe Pro Glu Tyr
                 320                 325                 330

 Arg Val Pro Thr Asp Pro Lys Ile Asp Lys Lys Ile Ile Arg Met
                 335                 340                 345

 Glu Gln Glu Lys Ala Phe Asn Met Leu Lys Lys Asn Leu Val Asp
                 350                 355                 360

 Ala Gly Gly Val Leu Arg Trp Tyr Val Gln Leu Pro Thr Gln Gln
                 365                 370                 375

 Ala His Gln Tyr His Glu Leu Glu Thr Pro Cys Leu Thr Leu Ser
                 380                 385                 390

 Pro Ser Pro Phe Pro Val Ser Ser Leu Glu Glu Glu Glu Thr Ala
                 395                 400                 405

 Val Arg Asp Glu Asn Cys Ala Leu Pro Ser Arg Leu His Pro Gln
                 410                 415                 420

 Val Ala His Lys Ile Gln Glu Leu Val Ser Gln Gly Ile Glu Gln
                 425                 430                 435

 Val Tyr Ala Val Arg Lys Gln Leu Arg Lys Phe Val Glu Arg Glu
                 440                 445                 450

 Leu Phe Lys Pro Asp Glu Val Pro Glu Arg His Asn Leu Ser Phe
                 455                 460                 465

 Phe Pro Thr Val Asn Asp Ile Lys Asn His Ile His Glu Val Gln
                 470                 475                 480

 Lys Ser Leu Arg Asn Gly Asp Thr Val Tyr Asn Ser Glu Ile Ile
                 485                 490                 495

 Pro Ala Thr Leu Gln Trp Thr Thr Asp Ser Gly Asn Ile Leu Lys
                 500                 505                 510

 Glu Thr Met Thr Val Thr Phe Ala Glu Gly Asn Ser Pro Gly Glu
                 515                 520                 525

 Ser Ile Thr Thr Lys Val Glu Thr Asn Gln Thr Arg Gly Ser Leu
                 530                 535                 540

 Ser Pro Glu Pro Thr His Leu Leu Ser Ser Leu Ser Ser Phe Gln
                 545                 550                 555

 Pro Lys Ile Phe Thr Gln Leu Gln Gly Leu Gln Leu Gln Pro Arg
                 560                 565                 570

 Tyr Thr Ser Pro Asp Glu Ser Pro Ala Val Val Ser Val Asn Asn
                 575                 580                 585

 Gln Pro Ser Ser Ser Pro Ser Gly Leu Leu Asp Thr Ile Gly Ser
                 590                 595                 600

 Ala Val Met Asn Asn Asn Ser Leu Leu Leu Gly Gln Ser His Ser
                 605                 610                 615

 Leu Gln Arg Asp Thr Cys Leu Thr Gln Asn Asn Ser Thr Ala Ser
                 620                 625                 630

 Thr Met Gly Asn Leu Pro Glu Pro Asp Gln Asn Leu Val Ala Met
                 635                 640                 645

 Asp Glu Leu Val Glu Val Gly Asp Val Glu Asp Thr Gly Asn Leu
                 650                 655                 660

 Glu Gly Thr Val His Arg Ile Leu Leu Gly Asp Val Gln Thr Ile
                 665                 670                 675

 Pro Ile Gln Ile Ile Asp Asn His Ser Ala Leu Ile Glu Glu Asn
                 680                 685                 690

 Pro Glu Ser Thr Ile Ser Val Ser Gln Val Lys Gln Glu Pro Lys
                 695                 700                 705

 Glu Pro Ala Leu Ser Met Glu Ala Lys Asn Cys Gly Leu
                 710                 715

<210> 3473
<211> 1420
<212> DNA
<213> Homo sapien

<400> 3473
 cccaaatata tatttaatct tgtggttcaa ataagctttt ggctcacatc 50

 taagcacatc ataaagaacg ctgtagaaga ggtgacatga tgaggcggga 100

 agacgaggaa gaggagggaa caatgatgaa ggcaaaaggg gacttagaga 150

 tgaaggagga ggaagagatt agtgagacag gagaactggt tggccctttt 200

 gtgagtgcta tgcccactcc aatgccccac aacaagggca cccggttctc 250

 tgaggcatgg gaatatttcc acctagctcc tgctcgtgct gggcaccatc 300

 ccaaccagta tgccacctgc cgcctgtgtg gcaggcaggt gagccgtggc 350

 cctggggtca acgtgggcac cactgcactg tggaagcatc tgaaaagcat 400

 gcacagagag gagctggaga agagtggcca tggtcaggct gggcagcgcc 450

 aggatccaag gccccacggg ccccagctcc ccacaggcat tgagggtaac 500

 tggggtaggc tcctggagca ggtgggcacc atggctttgt gggccagcca 550

 aagggaaaag gaggtgctta ggagggaaag ggcagtggaa tggcgggaga 600

 gggctgtgga aaaaagggag cgagccctgg aggaggtgga aagggccatc 650

 ctggagatga agtggaaggt gagggctgag aaggaggcat gccagcggga 700

 gaaagagctg cctgcagcag tacatccctt ccattttgtt taaattgggc 750

 ttggagaatc tattctgaaa acattgactc tagacttgta gaaaagagcc 800

 attttagttt caactcaaat gtaaagcaaa gtagtttggt gacattttgc 850

 ttttatgtga aatagtgcac agtatgagtt aatctgagca ggtctgaatt 900

 gaccaaatgc ttatctacga ggttcctaga gctctgctga cccttggccg 950

 aaactctaaa atgtacctat taaagataaa tgcttctacc aaagtaaaac 1000

 tctgtgagtt gtttcagggc agaatgtacc agccagtcag cgttgtttaa 1050

 caaaataatc agatttttgc ctagcactcg gttttggtgg agctgacgat 1100

 tttgagggct gaggctggtt aggtagctgg aatgtgccta tgtgaccagc 1150

 tcacttgcag acaccctgcc ggaagcagag cttaatcttc ctaggactga 1200

 ggtcttagca catgtactgg tggagtttcc agaccaccag tatgaataaa 1250

 agcttgttct gtgtgaccca gcaagtggaa ggacaaagaa ctgtgagcct 1300

 cagatctttg gacctttcca atgcgtctct ttctcctgtt attgctgcaa 1350

 tgtattttct tgcttatatt aaagttgttt catcagtaaa aaaaaaaaaa 1400

 aaaaaaaaaa aaaaaaaaaa 1420

<210> 3474
<211> 217
<212> PRT
<213> Homo sapien

<400> 3474
 Met Arg Arg Glu Asp Glu Glu Glu Glu Gly Thr Met Met Lys Ala
   1               5                  10                  15

 Lys Gly Asp Leu Glu Met Lys Glu Glu Glu Glu Ile Ser Glu Thr
                  20                  25                  30

 Gly Glu Leu Val Gly Pro Phe Val Ser Ala Met Pro Thr Pro Met
                  35                  40                  45

 Pro His Asn Lys Gly Thr Arg Phe Ser Glu Ala Trp Glu Tyr Phe
                  50                  55                  60

 His Leu Ala Pro Ala Arg Ala Gly His His Pro Asn Gln Tyr Ala
                  65                  70                  75

 Thr Cys Arg Leu Cys Gly Arg Gln Val Ser Arg Gly Pro Gly Val
                  80                  85                  90

 Asn Val Gly Thr Thr Ala Leu Trp Lys His Leu Lys Ser Met His
                  95                 100                 105

 Arg Glu Glu Leu Glu Lys Ser Gly His Gly Gln Ala Gly Gln Arg
                 110                 115                 120

 Gln Asp Pro Arg Pro His Gly Pro Gln Leu Pro Thr Gly Ile Glu
                 125                 130                 135

 Gly Asn Trp Gly Arg Leu Leu Glu Gln Val Gly Thr Met Ala Leu
                 140                 145                 150

 Trp Ala Ser Gln Arg Glu Lys Glu Val Leu Arg Arg Glu Arg Ala
                 155                 160                 165

 Val Glu Trp Arg Glu Arg Ala Val Glu Lys Arg Glu Arg Ala Leu
                 170                 175                 180

 Glu Glu Val Glu Arg Ala Ile Leu Glu Met Lys Trp Lys Val Arg
                 185                 190                 195

 Ala Glu Lys Glu Ala Cys Gln Arg Glu Lys Glu Leu Pro Ala Ala
                 200                 205                 210

 Val His Pro Phe His Phe Val
                 215

<210> 3475
<211> 2891
<212> DNA
<213> Homo sapien

<400> 3475
 tcctgaaggc cgaaggtggc tctagcgcat cctttgtcgc gccgtgacct 50

 gcaggtactg acagatccgt agggaggaca ccgtgacttc ccggacgctg 100

 ggaaatggac tcagtctcct ttgaggatgt ggccgtgaac ttcaccctgg 150

 aggagtgggc tttgctggat tcttcacaga aaaagctcta tgaagatgtg 200

 atgcaggaga ccttcaaaaa cctggtttgt ctaggaaaaa agtgggaaga 250

 ccaggacatt gaagatgacc acagaaacca ggggaaaaat cgaagatgtc 300

 atatggttga gagactctgt gaaagtagaa gaggtagcaa atgtggagaa 350

 accactagcc agatgccaaa tgttaatatc aacaaggaaa cttttactgg 400

 agcaaaacca catgaatgca gcttttgtgg aagagacttc attcatcatt 450

 cgtcccttaa taggcacatg agatctcaca ctggacagaa accaaatgag 500

 tatcaggaat atgaaaagca accatgtaaa tgtaaagcag ttgggaaaac 550

 cttcagttat caccactgct ttcgcaaaca tgaaagaact cacactggag 600

 tgaagcccta tgaatgtaaa cagtgtggga aagcctttat atattaccag 650

 ccatttcaaa gacatgaaag gactcatgct ggacagaaac cctatgaatg 700

 taagcaatgt ggaaaaacct ttatatatta ccagtctttt caaaaacatg 750

 ctcatactgg aaagaaaccc tatgaatgta aacagtgtgg gaaagccttt 800

 atatgttacc aatcttttca aagacacaaa aggactcaca ctggagagaa 850

 accctatgaa tgtaagcaat gtggtaaggc tttcagttgt cccacatact 900

 ttcgaactca tgaaagaact cactctggag aaaaacccta caaatgtaaa 950

 gaatgtggta aagccttcag ttttctcagt tcttttcgaa ggcataaaag 1000

 gactcatagt ggagagaaac cctatgaatg taaagaatgt ggaaaagcct 1050

 tcttttattc tgcaagcttt cgagcacatg taataataca cactggggct 1100

 cgaccttata aatgtaaaga atgtgggaaa gccttcaact cttctaattc 1150

 ctgtcgagtg catgaaagaa ctcatattgg agaaaaacca tatgaatgta 1200

 aacgatgtgg caaatcattc agttggtcca tttctcttcg attgcatgaa 1250

 agaactcata ctggagagaa accttatgag tgtaaacagt gtcataaaac 1300

 cttcagtttt tcaagttccc ttcgagaaca cgaaacaact cacactggag 1350

 agaaacccta tgaatgtaaa caatgtggta aaaccttcag tttttcaagt 1400

 tcccttcaaa gacatgaaag gactcacaat gcagagaaac cctatgaatg 1450

 taaacagtgt gggaaagcct tcaggtgttc aagttatttt cgaattcatg 1500

 aaaggtcaca cactggagag aaaccctatg aatgtaaaca gtgtggaaaa 1550

 gttttcattc gttccagttc ctttcgactg catgaaagaa cacacactgg 1600

 agagaaaccc tatgaatgta aactatgcgg taaaaccttc agtttttcaa 1650

 gttcccttcg agaacatgaa aaaattcaca ctggaaataa gccttttgag 1700

 tgtaagcaat gtggtaaggc cttccttcgt tccagtcaaa ttcgattgca 1750

 tgaaaggact cacactggag agaaaccgta tcaatgtaaa caatgtggaa 1800

 aagccttcat ttcttccagt aaatttcgaa tgcatgagag aactcacacg 1850

 ggagagaaac cctatcgatg taaacaatgt gggaaagcct tcagattttc 1900

 aagttctgtt cgaattcatg aaaggtctca cactggagag aaaccttatg 1950

 aatgcaaaca atgtggaaaa gccttcattt cttccagtca ctttcgactg 2000

 catgaaagga ctcatatggg agagaaagtc taagaatata agcaacattc 2050

 tgaagccttc ggttgttcca gctccttctg aatacacaaa agagttcata 2100

 ctggacagaa gctgtgtgaa tacaaacatt gttctaaagc ccttgattgt 2150

 tccagtttct tttgagcacg aaagaattcc cactggtgag aaacagtatg 2200

 aatgtaaaca ttgtgattaa gccttcagtt gacctaattc atttcaaaga 2250

 caggactcgt gctgcagtga aatctgtttt gttttttgtt ttttgttttt 2300

 ttaaaaaagg ccaagcttgt tggctcatgc ctatagtccc agcactttgg 2350

 gaggccaagg tgcaaggcgg gcagatcatt tgaggtcaga aattcgagac 2400

 cagcgtggtc aacatggtgt aaccccatct ctactaaaaa ttaccaaaaa 2450

 atgaaccagg catggtagtg catgcctcta atcccagcta ctcaggaggc 2500

 taaggcagga gaatcacttg aacctggaga cagaggttgc agtgagctga 2550

 gatcacgcca ctgcattcca gcctgtgcga cagaatgaga cactgtctca 2600

 agaaaaaata aaagtgggaa aatcttccaa ctgtcctcta gagtgtgaat 2650

 atatgaaagg agtcagagtg gggtgaaagt ctataaatgt aagacatttg 2700

 ggaaagcctt cacacagcct tttgagcaca catgagaatg tatactggag 2750

 agaaacccta taaatattaa gaatgtggga aattcttcat cctagttctt 2800

 ttgttgttgt tgatgataca aaaataattt catttaataa agattgtcag 2850

 gttatattta ataagaaaga aagtatcatg taaacagccc a 2891

<210> 3476
<211> 642
<212> PRT
<213> Homo sapien

<400> 3476
 Met Asp Ser Val Ser Phe Glu Asp Val Ala Val Asn Phe Thr Leu
   1               5                  10                  15

 Glu Glu Trp Ala Leu Leu Asp Ser Ser Gln Lys Lys Leu Tyr Glu
                  20                  25                  30

 Asp Val Met Gln Glu Thr Phe Lys Asn Leu Val Cys Leu Gly Lys
                  35                  40                  45

 Lys Trp Glu Asp Gln Asp Ile Glu Asp Asp His Arg Asn Gln Gly
                  50                  55                  60

 Lys Asn Arg Arg Cys His Met Val Glu Arg Leu Cys Glu Ser Arg
                  65                  70                  75

 Arg Gly Ser Lys Cys Gly Glu Thr Thr Ser Gln Met Pro Asn Val
                  80                  85                  90

 Asn Ile Asn Lys Glu Thr Phe Thr Gly Ala Lys Pro His Glu Cys
                  95                 100                 105

 Ser Phe Cys Gly Arg Asp Phe Ile His His Ser Ser Leu Asn Arg
                 110                 115                 120

 His Met Arg Ser His Thr Gly Gln Lys Pro Asn Glu Tyr Gln Glu
                 125                 130                 135

 Tyr Glu Lys Gln Pro Cys Lys Cys Lys Ala Val Gly Lys Thr Phe
                 140                 145                 150

 Ser Tyr His His Cys Phe Arg Lys His Glu Arg Thr His Thr Gly
                 155                 160                 165

 Val Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala Phe Ile Tyr
                 170                 175                 180

 Tyr Gln Pro Phe Gln Arg His Glu Arg Thr His Ala Gly Gln Lys
                 185                 190                 195

 Pro Tyr Glu Cys Lys Gln Cys Gly Lys Thr Phe Ile Tyr Tyr Gln
                 200                 205                 210

 Ser Phe Gln Lys His Ala His Thr Gly Lys Lys Pro Tyr Glu Cys
                 215                 220                 225

 Lys Gln Cys Gly Lys Ala Phe Ile Cys Tyr Gln Ser Phe Gln Arg
                 230                 235                 240

 His Lys Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln
                 245                 250                 255

 Cys Gly Lys Ala Phe Ser Cys Pro Thr Tyr Phe Arg Thr His Glu
                 260                 265                 270

 Arg Thr His Ser Gly Glu Lys Pro Tyr Lys Cys Lys Glu Cys Gly
                 275                 280                 285

 Lys Ala Phe Ser Phe Leu Ser Ser Phe Arg Arg His Lys Arg Thr
                 290                 295                 300

 His Ser Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala
                 305                 310                 315

 Phe Phe Tyr Ser Ala Ser Phe Arg Ala His Val Ile Ile His Thr
                 320                 325                 330

 Gly Ala Arg Pro Tyr Lys Cys Lys Glu Cys Gly Lys Ala Phe Asn
                 335                 340                 345

 Ser Ser Asn Ser Cys Arg Val His Glu Arg Thr His Ile Gly Glu
                 350                 355                 360

 Lys Pro Tyr Glu Cys Lys Arg Cys Gly Lys Ser Phe Ser Trp Ser
                 365                 370                 375

 Ile Ser Leu Arg Leu His Glu Arg Thr His Thr Gly Glu Lys Pro
                 380                 385                 390

 Tyr Glu Cys Lys Gln Cys His Lys Thr Phe Ser Phe Ser Ser Ser
                 395                 400                 405

 Leu Arg Glu His Glu Thr Thr His Thr Gly Glu Lys Pro Tyr Glu
                 410                 415                 420

 Cys Lys Gln Cys Gly Lys Thr Phe Ser Phe Ser Ser Ser Leu Gln
                 425                 430                 435

 Arg His Glu Arg Thr His Asn Ala Glu Lys Pro Tyr Glu Cys Lys
                 440                 445                 450

 Gln Cys Gly Lys Ala Phe Arg Cys Ser Ser Tyr Phe Arg Ile His
                 455                 460                 465

 Glu Arg Ser His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys
                 470                 475                 480

 Gly Lys Val Phe Ile Arg Ser Ser Ser Phe Arg Leu His Glu Arg
                 485                 490                 495

 Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Leu Cys Gly Lys
                 500                 505                 510

 Thr Phe Ser Phe Ser Ser Ser Leu Arg Glu His Glu Lys Ile His
                 515                 520                 525

 Thr Gly Asn Lys Pro Phe Glu Cys Lys Gln Cys Gly Lys Ala Phe
                 530                 535                 540

 Leu Arg Ser Ser Gln Ile Arg Leu His Glu Arg Thr His Thr Gly
                 545                 550                 555

 Glu Lys Pro Tyr Gln Cys Lys Gln Cys Gly Lys Ala Phe Ile Ser
                 560                 565                 570

 Ser Ser Lys Phe Arg Met His Glu Arg Thr His Thr Gly Glu Lys
                 575                 580                 585

 Pro Tyr Arg Cys Lys Gln Cys Gly Lys Ala Phe Arg Phe Ser Ser
                 590                 595                 600

 Ser Val Arg Ile His Glu Arg Ser His Thr Gly Glu Lys Pro Tyr
                 605                 610                 615

 Glu Cys Lys Gln Cys Gly Lys Ala Phe Ile Ser Ser Ser His Phe
                 620                 625                 630

 Arg Leu His Glu Arg Thr His Met Gly Glu Lys Val
                 635                 640

<210> 3477
<211> 3246
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2530
<223> Unknown base

<400> 3477
 agtgtggttt tagtttttcc taagaagtgg cgtggtttgg ggctttatat 50

 ccgggaggag catatgtacg caaatcctgg ggcgtttgca aacccggatc 100

 cggggcgtct ggccccatgc ccggccgggc gtttgagggc tactgccacg 150

 cagcgtttct ggagcctgcc ggctggtgcc ctggtggcct ttatctctgt 200

 ccccctttgt cctctttatc tcaggctctc caggaggccg gggggcccac 250

 tccgcctatc gctcccctcg gctacgctgc cactccaatg ccccgcaggt 300

 cgcgagctgc tgttctttcg aaggcgccgg agaaccaggg gcgtcccgcg 350

 ccacctctga ctcggagcag cgccgagcac tgacgctccc gcccttgggc 400

 aaggacgcca gtgcgcccgc gcgcgtccct ctgcgcggca gcccgtcgcg 450

 ggccctcaag gggaagccca ggccaggatg gccccgggtc gcgcggtggc 500

 cgggctcctg ttgctggcgg ccgccggcct cggaggagtg gcggaggggc 550

 cagggctagc cttcagcgag gatgtgctga gcgtgttcgg cgcgaatctg 600

 agcctgtcgg cggcgcagct ccagcacttg ctggagcaga tgggagccgc 650

 ctcccgcgtg ggcgtcccgg agcctggcca gctgcacttc aaccagtgtt 700

 taactgctga agagatcttt tcccttcatg gcttttcaaa tgctacccaa 750

 ataaccagct ccaaattctc tgtcatctgt ccagcagtct tacagcaatt 800

 gaactttcac ccatgtgagg atcggcccaa gcacaaaaca agaccaagtc 850

 attcagaagt ttggggatat ggattcctgt cagtgacgat tattaatctg 900

 gcatctctcc tcggattgat tttgactcca ctgataaaga aatcttattt 950

 cccaaagatt ttgacctttt ttgtggggct ggctattggg actctttttt 1000

 caaatgcaat tttccaactt attccagagg catttggatt tgatcccaaa 1050

 gtcgacagtt atgttgagaa ggcagttgct gtgtttggtg gattttacct 1100

 acttttcttt tttgaaagaa tgctaaagat gttattaaag acatatggtc 1150

 agaatggtca tacccacttt ggaaatgata actttggtcc tcaagaaaaa 1200

 actcatcaac ctaaagcatt acctgccatc aatggtgtga catgctatgc 1250

 aaatcctgct gtcacagaag ctaatggaca tatccatttt gataatgtca 1300

 gtgtggtatc tctacaggat ggaaaaaaag agccaagttc atgtacctgt 1350

 ttgaaggggc ccaaactgtc agaaataggg acgattgcct ggatgataac 1400

 gctctgcgat gccctccaca atttcatcga tggcctggcg attggggctt 1450

 cctgcacctt gtctctcctt cagggactca gtacttccat agcaatccta 1500

 tgtgaggagt ttccccacga gttaggagac tttgtgatcc tactcaatgc 1550

 agggatgagc actcgacaag ccttgctatt caacttcctt tctgcatgtt 1600

 cctgctatgt tgggctagct tttggcattt tggtgggcaa caatttcgct 1650

 ccaaatatta tatttgcact tgctggaggc atgttcctct atatttctct 1700

 ggcagatatg tttccagaga tgaatgatat gctgagagaa aaggtaactg 1750

 gaagaaaaac cgatttcacc ttcttcatga ttcagaatgc tggaatgtta 1800

 actggattca cagccattct actcattacc ttgtatgcag gagaaatcga 1850

 attggagtaa tagaaaatgg aagatggtgt tgttaataaa ggcatttaat 1900

 agataaaaac atctccaaaa aggattttga agctgatcct atttagttaa 1950

 aaagataatt ttgctttcaa ctgtaggtcc agaaaactaa ttattggcat 2000

 cagtctgtga aatagtccat tatttgttgt taaaaatgct tcaaaaggtt 2050

 ttcagtgtca gtctgagatg cctggtatat aggagccttt gggaaatact 2100

 tatttttcag tattccatgc atattagata tcaccatgaa gcaagagaca 2150

 tgcattctat aatcatgtag acactcagac tcaggggaaa atacaagtta 2200

 tatcctgaaa gcctttaaaa ctctatggta ggatcaaaga ttcaaatggt 2250

 ttcagagagg ttttatttca attaatttgt tctagtgctt tcaagagcaa 2300

 gtacatcaaa atgtagaagg taaaatgtat gcaacactaa tataaattat 2350

 tccaagtctt taaggagcca aagaaaaaaa agatttctca cagctttttg 2400

 ttctgttttg tatttcaatt aggaacttgc agtattattt tgaaaaccat 2450

 tctaaaataa taggagttag gaaataaata aagttttgct agccctgcta 2500

 agttcaggct tagaggctta tcgctaagtn taaacttcac cagattccac 2550

 gaaaagctgg atagcttttt ttctgactta tgttgtggtt gcacccctca 2600

 caaatggcag aacagtatgt aaagctggta acacctcggt ttcagtgcac 2650

 catgtgtttg ctttgtgaag gtgaagaata tgttggttta gagaaagaaa 2700

 ttggatgtaa ttttatgcaa tttactttta aagacaaaca taactattta 2750

 gcagagaata ttttaataaa tgcaaaacaa cagctggact gctgtacatc 2800

 aaggacagat taactggaaa acatatgttc cttatgtgtg attgagagcc 2850

 attcagaaaa gacttccttt gtgttcagcc tatacttttc catatggtat 2900

 accttgaaaa aaattagcac accatggtta tttttctacc ttttataaaa 2950

 gacagagcct gtttactcat ttagaagata gagaaaattg gtctaaaatt 3000

 gaacatccta gattcacact cccaagtcac ttaaggtgat ttgatggtga 3050

 ggaaaatgat tgacaaagcc caacaatgat ctcaggaatt acattttcca 3100

 acagaccaaa aaatgttttc atgtagcagc aatgcagatt tggtgaatat 3150

 ttaatatata ttttagtatg tatttcactt tatgactgac aattaaaaaa 3200

 tattgtttgg ccaaatagta aacacccttt tgaaaccatg aaaaaa 3246

<210> 3478
<211> 460
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2530
<223> Unknown amino acid

<400> 3478
 Met Ala Pro Gly Arg Ala Val Ala Gly Leu Leu Leu Leu Ala Ala
   1               5                  10                  15

 Ala Gly Leu Gly Gly Val Ala Glu Gly Pro Gly Leu Ala Phe Ser
                  20                  25                  30

 Glu Asp Val Leu Ser Val Phe Gly Ala Asn Leu Ser Leu Ser Ala
                  35                  40                  45

 Ala Gln Leu Gln His Leu Leu Glu Gln Met Gly Ala Ala Ser Arg
                  50                  55                  60

 Val Gly Val Pro Glu Pro Gly Gln Leu His Phe Asn Gln Cys Leu
                  65                  70                  75

 Thr Ala Glu Glu Ile Phe Ser Leu His Gly Phe Ser Asn Ala Thr
                  80                  85                  90

 Gln Ile Thr Ser Ser Lys Phe Ser Val Ile Cys Pro Ala Val Leu
                  95                 100                 105

 Gln Gln Leu Asn Phe His Pro Cys Glu Asp Arg Pro Lys His Lys
                 110                 115                 120

 Thr Arg Pro Ser His Ser Glu Val Trp Gly Tyr Gly Phe Leu Ser
                 125                 130                 135

 Val Thr Ile Ile Asn Leu Ala Ser Leu Leu Gly Leu Ile Leu Thr
                 140                 145                 150

 Pro Leu Ile Lys Lys Ser Tyr Phe Pro Lys Ile Leu Thr Phe Phe
                 155                 160                 165

 Val Gly Leu Ala Ile Gly Thr Leu Phe Ser Asn Ala Ile Phe Gln
                 170                 175                 180

 Leu Ile Pro Glu Ala Phe Gly Phe Asp Pro Lys Val Asp Ser Tyr
                 185                 190                 195

 Val Glu Lys Ala Val Ala Val Phe Gly Gly Phe Tyr Leu Leu Phe
                 200                 205                 210

 Phe Phe Glu Arg Met Leu Lys Met Leu Leu Lys Thr Tyr Gly Gln
                 215                 220                 225

 Asn Gly His Thr His Phe Gly Asn Asp Asn Phe Gly Pro Gln Glu
                 230                 235                 240

 Lys Thr His Gln Pro Lys Ala Leu Pro Ala Ile Asn Gly Val Thr
                 245                 250                 255

 Cys Tyr Ala Asn Pro Ala Val Thr Glu Ala Asn Gly His Ile His
                 260                 265                 270

 Phe Asp Asn Val Ser Val Val Ser Leu Gln Asp Gly Lys Lys Glu
                 275                 280                 285

 Pro Ser Ser Cys Thr Cys Leu Lys Gly Pro Lys Leu Ser Glu Ile
                 290                 295                 300

 Gly Thr Ile Ala Trp Met Ile Thr Leu Cys Asp Ala Leu His Asn
                 305                 310                 315

 Phe Ile Asp Gly Leu Ala Ile Gly Ala Ser Cys Thr Leu Ser Leu
                 320                 325                 330

 Leu Gln Gly Leu Ser Thr Ser Ile Ala Ile Leu Cys Glu Glu Phe
                 335                 340                 345

 Pro His Glu Leu Gly Asp Phe Val Ile Leu Leu Asn Ala Gly Met
                 350                 355                 360

 Ser Thr Arg Gln Ala Leu Leu Phe Asn Phe Leu Ser Ala Cys Ser
                 365                 370                 375

 Cys Tyr Val Gly Leu Ala Phe Gly Ile Leu Val Gly Asn Asn Phe
                 380                 385                 390

 Ala Pro Asn Ile Ile Phe Ala Leu Ala Gly Gly Met Phe Leu Tyr
                 395                 400                 405

 Ile Ser Leu Ala Asp Met Phe Pro Glu Met Asn Asp Met Leu Arg
                 410                 415                 420

 Glu Lys Val Thr Gly Arg Lys Thr Asp Phe Thr Phe Phe Met Ile
                 425                 430                 435

 Gln Asn Ala Gly Met Leu Thr Gly Phe Thr Ala Ile Leu Leu Ile
                 440                 445                 450

 Thr Leu Tyr Ala Gly Glu Ile Glu Leu Glu
                 455                 460

<210> 3479
<211> 2423
<212> DNA
<213> Homo sapien

<400> 3479
 taagaaactg aaagaattga accaacgcat tgggaagaca gagtgcagaa 50

 ataagcatga aggaatagct gataaacttt tggcaaaaat agcaaaactt 100

 caaagacgta ttaaaacagt attattattt caaaggaatt gtttgaaacc 150

 aaacatgtta tccagtaatg gagcctctaa ggttgcaaat tcagaggcta 200

 tgattttgga taagaatctt gagtcagtta atagtccaat tgaaaagtct 250

 tctgtgaatt atgagccttc taacccttcc gaaaaaggaa gtaaaaaaat 300

 taatttgtca tcagatcaaa ataagtctgt ttctgaaagt aacaatgatg 350

 atgttatgtt gatttctgtg gaaagtccta atttgacaac tccaactaca 400

 tcaaatccaa cagataccag aaaaattaca tcaggaaatt ctagcaattc 450

 tcccaatgct gaagttatgg ctgtacagaa gaaacttgat tctataattg 500

 atttgacaaa agaaggccta tccaactgca atacagaaag tccagtatcc 550

 cccctggagt cacattcgaa agctgcttca aactcaaagg aaacaacccc 600

 attggcacaa aatgcagtcc aggttcctga gtcctttgag cacctgccac 650

 ctctcccaga accaccagca ccactacctg aattagtaga caaaacccga 700

 gacacacttc ctccccagaa gcctgagctc aaagtgaaac gggttttcag 750

 accaaatggc attgccctga cttggaatat aaccaaaatc aatcccaagt 800

 gtgctcctgt agaaagctac cacctcttcc tgtgtcatga gaactctaat 850

 aataagttga tttggaagaa gattggagaa attaaagctt taccactccc 900

 catggcctgt actttatctc agtttttagc ttccaacaga tactatttta 950

 ccgtccaatc aaaagatatt tttggacgat atggaccatt ctgtgatata 1000

 aaatctatcc ctgggttttc tgaaaatctt acgtaaaagg tgtttaataa 1050

 tgatatacta cttttttttt catatttgtt tgtttgcaat gttactgtaa 1100

 tactatttgc cattgtaaaa ggccagctca gattgtgagc cctttctatt 1150

 gggacagtcc tcttctatat gttttaagtg gccagtaatt taatgaattt 1200

 ctggtttgta ttaaatatgt ccttccaatg gataagttct aaaacatacg 1250

 ctatcattgg cccatgttgc tgaggtgcat tgtgaacaat acctttagtg 1300

 actgtggaac tgctgcttct atcagaagac ctaggataca agcagccact 1350

 gtttcctccg ttaacaatca gcttttagta acctgctgtg gtcagcatag 1400

 ctacaggaaa agtcagccct tgactgaggg ccagatcatc cctggagtgc 1450

 acctctacta agattttatg aaaagatgac atgttgggct gcatgataaa 1500

 agttaattat aaaaattaaa agattttttt ttttgagatg gaatattgct 1550

 ctgttgccca ggctggagta cagtggtcac tgcaacctcc atctccctgg 1600

 ctcaagcaat tctcctatgt cagcctccca agtagctggg actatagtca 1650

 cttgccacca tgcccggcta atttattttt agtagagatg aggtttcacc 1700

 ttgttggtca ggctggtctc aaactcctga cctcagggga tccacccgcc 1750

 tcggcttccc gaagtgctgg gattataggc gtaagccacc atgcctggcc 1800

 aaaaattaaa agattttatg aaacgaaatg gcttcccatt ctttctattc 1850

 agcttctaag tgggctattc atttgtgctc tcctcttttt tgtttgtttt 1900

 gcactttgtc aatcatttgg ggaaatagcc tggaggtctt tcctgaatct 1950

 gtttgtagac ataataaaat ttgtgtgctg tgtacacaaa aacataatgt 2000

 atcttatgaa agcattaccc aacctgtttg agttgagaat gcatttgtcc 2050

 acctttgatt tgaggcttta gtttgctgat ttcctaaatg ctaccctttg 2100

 atcatttcct ggccaccatc acaatactaa ggggctcaga tgtgtcttgt 2150

 gcccacctct tcctgagaag agatggaagt ggagctgtga ctagtacaag 2200

 cagcccaaga aactctgaac gggacccaat ggaggcaaac ttgagcaaat 2250

 aattgggatg ataagaaaca aaaataatcc caactgtttg aaagttcgaa 2300

 agaggggcat tcttttctgg tacatggtga gagttcaggc tccagagact 2350

 caaaacggaa tggttttcct tggcattttg taaatgctct cacatctgta 2400

 gcaataaagc tgttattttc tgc 2423

<210> 3480
<211> 293
<212> PRT
<213> Homo sapien

<400> 3480
 Met Leu Ser Ser Asn Gly Ala Ser Lys Val Ala Asn Ser Glu Ala
   1               5                  10                  15

 Met Ile Leu Asp Lys Asn Leu Glu Ser Val Asn Ser Pro Ile Glu
                  20                  25                  30

 Lys Ser Ser Val Asn Tyr Glu Pro Ser Asn Pro Ser Glu Lys Gly
                  35                  40                  45

 Ser Lys Lys Ile Asn Leu Ser Ser Asp Gln Asn Lys Ser Val Ser
                  50                  55                  60

 Glu Ser Asn Asn Asp Asp Val Met Leu Ile Ser Val Glu Ser Pro
                  65                  70                  75

 Asn Leu Thr Thr Pro Thr Thr Ser Asn Pro Thr Asp Thr Arg Lys
                  80                  85                  90

 Ile Thr Ser Gly Asn Ser Ser Asn Ser Pro Asn Ala Glu Val Met
                  95                 100                 105

 Ala Val Gln Lys Lys Leu Asp Ser Ile Ile Asp Leu Thr Lys Glu
                 110                 115                 120

 Gly Leu Ser Asn Cys Asn Thr Glu Ser Pro Val Ser Pro Leu Glu
                 125                 130                 135

 Ser His Ser Lys Ala Ala Ser Asn Ser Lys Glu Thr Thr Pro Leu
                 140                 145                 150

 Ala Gln Asn Ala Val Gln Val Pro Glu Ser Phe Glu His Leu Pro
                 155                 160                 165

 Pro Leu Pro Glu Pro Pro Ala Pro Leu Pro Glu Leu Val Asp Lys
                 170                 175                 180

 Thr Arg Asp Thr Leu Pro Pro Gln Lys Pro Glu Leu Lys Val Lys
                 185                 190                 195

 Arg Val Phe Arg Pro Asn Gly Ile Ala Leu Thr Trp Asn Ile Thr
                 200                 205                 210

 Lys Ile Asn Pro Lys Cys Ala Pro Val Glu Ser Tyr His Leu Phe
                 215                 220                 225

 Leu Cys His Glu Asn Ser Asn Asn Lys Leu Ile Trp Lys Lys Ile
                 230                 235                 240

 Gly Glu Ile Lys Ala Leu Pro Leu Pro Met Ala Cys Thr Leu Ser
                 245                 250                 255

 Gln Phe Leu Ala Ser Asn Arg Tyr Tyr Phe Thr Val Gln Ser Lys
                 260                 265                 270

 Asp Ile Phe Gly Arg Tyr Gly Pro Phe Cys Asp Ile Lys Ser Ile
                 275                 280                 285

 Pro Gly Phe Ser Glu Asn Leu Thr
                 290

<210> 3481
<211> 2349
<212> DNA
<213> Homo sapien

<400> 3481
 ggaattagcc tcctcaatga aaaagaaaga gggggaggaa gaggaagaga 50

 aaagaagaag aaaaccctga acatggtttc attggatatt cacccgaact 100

 gctacagaac aacacgctgc ccgattacag cccgggggaa tcttttttca 150

 ctgtctttgg ggttttcttc ccagcggcta caggagtcat ggccggttca 200

 acatgggggg cgacctcagg gagcctgccg ccagcattcc cctgggctcc 250

 ctggcagctg ttggcatctc gtggtttctg tacatcgtct tcgtcttcct 300

 cctgggcgcc atctgcactc gagaggccct tcgctatgac ttcctgatag 350

 cggaaaaggt atccctcatg ggcttcctgt tccttttggg cttatacatc 400

 tcgtccctgg cttcctgcat gggaggactt tatggagctc cccgcatcct 450

 gcagtgcatt gcccaggaga aagtgatccc tgcacttgcc tgtctgggac 500

 aagggaaggg gccaaacaaa acacccgtgg ctgccatctg cctgaccagc 550

 ttggtgacca tggcctttgt ttttgtgggt caagtgaacg ttctggcccc 600

 catcgtcacc atcaacttca tgcttgacat acgttgcagt ggactactct 650

 tacttctccc tgtccatgtg ttcctgcagc ctgaccccgg tgcctgagcc 700

 ggtgctcagg gagggcgcag aaggcctcca ctgctctgag cacctgctct 750

 tagagaaagc tcccagttac ggctctgagg gacctgccca aagagtcttg 800

 gagggcacgc tactggaatt caccaaggac atggatcagc tcctccagct 850

 aaccaggaag cttgagagta gccagcccag gcaaggagat ggtaacagga 900

 ccccagaaag tcagaagagg aaaagcaaga aggccaccaa gcagacccta 950

 caagatagct tcctcttgga cctcaaatcc cctccttctt tccctgtcga 1000

 gatctctgac aggttgcccg ctgcctcctg ggaggggcag gagtcctgct 1050

 ggaacaagca gacttccaag agcgaaggga ctcagcctga gggaacatat 1100

 ggagagcaac ttgttcctga gctgtgcaac caatcagagt ccagtggaga 1150

 agatttcttc ctgaagtcca ggctccaaga acaagatgtc tggagaagat 1200

 ccacttcttt ctatacccac atgtgcaacc cctgggtctc cctgttgggg 1250

 gctgttgggt cccttctcat catgtttgtg atacagtggg tgtataccct 1300

 ggttaacatg ggtgttgctg ccatcgtgta tttctacatt ggccgggcca 1350

 gtccagggct tcaccttgga tcagcctcca acttcagctt tttccggtgg 1400

 atgaggtctc tcttgctccc ctcctgcagg agcttgcagt ccccccagga 1450

 gcagatcatc ttggcgccgt ccctggctaa ggttgacatg gagatgactc 1500

 agctcaccca ggagaatgca gacttcgcca ctcgggatcg ctaccaccac 1550

 tcctccctcg tgaaccggga gcagctgatg cctcactact agatgcagtg 1600

 ctgggacctt cctcttttgg agctgtccca tgtacagtgg acccaagccc 1650

 aggaccttcg tggagctgct tctccaacct gagaaactca agacccatcc 1700

 tcccgctgtc actttggaca atggaaatct acattttctt ttcccttttt 1750

 ttttttttga gacagagtct cgccttgtca cccaggctgg agtccagtgg 1800

 cacaatcttg gctcactgca acctctgctt cccgagttca agcaattctc 1850

 ctgcctcagc tctgagtagc tgggattata ggcatgcacc accaccaccc 1900

 agctattttt tgtattttta ctggagacag ggtttcacca tgttggccag 1950

 gctggtctcg aactcctgac ctcgtgatcc acccgtctca gcctcccaaa 2000

 gtactgggat tacaggcgtg agccaccatg cctggccaga aatctatgtt 2050

 ttcttagaac atgtggaaga aggaaaaaga caaaaaggaa gtctggattc 2100

 tgaggaccac gtctcaccca gggtgacatc aggaatggtg ctagcctctg 2150

 caacacgaca cccagtttga agagctctat acaggtacta agactagcag 2200

 gggacaccaa gactctgcac aaccagattg cttgtgcaga gggccacaat 2250

 aagtgtatgt tttatatttt attgtattat ttattcaaaa ataaataata 2300

 cactcacatg tttccacacc caaaaaaaaa aaaaaaaaaa aaaaaaaaa 2349

<210> 3482
<211> 308
<212> PRT
<213> Homo sapien

<400> 3482
 Met Cys Ser Cys Ser Leu Thr Pro Val Pro Glu Pro Val Leu Arg
   1               5                  10                  15

 Glu Gly Ala Glu Gly Leu His Cys Ser Glu His Leu Leu Leu Glu
                  20                  25                  30

 Lys Ala Pro Ser Tyr Gly Ser Glu Gly Pro Ala Gln Arg Val Leu
                  35                  40                  45

 Glu Gly Thr Leu Leu Glu Phe Thr Lys Asp Met Asp Gln Leu Leu
                  50                  55                  60

 Gln Leu Thr Arg Lys Leu Glu Ser Ser Gln Pro Arg Gln Gly Asp
                  65                  70                  75

 Gly Asn Arg Thr Pro Glu Ser Gln Lys Arg Lys Ser Lys Lys Ala
                  80                  85                  90

 Thr Lys Gln Thr Leu Gln Asp Ser Phe Leu Leu Asp Leu Lys Ser
                  95                 100                 105

 Pro Pro Ser Phe Pro Val Glu Ile Ser Asp Arg Leu Pro Ala Ala
                 110                 115                 120

 Ser Trp Glu Gly Gln Glu Ser Cys Trp Asn Lys Gln Thr Ser Lys
                 125                 130                 135

 Ser Glu Gly Thr Gln Pro Glu Gly Thr Tyr Gly Glu Gln Leu Val
                 140                 145                 150

 Pro Glu Leu Cys Asn Gln Ser Glu Ser Ser Gly Glu Asp Phe Phe
                 155                 160                 165

 Leu Lys Ser Arg Leu Gln Glu Gln Asp Val Trp Arg Arg Ser Thr
                 170                 175                 180

 Ser Phe Tyr Thr His Met Cys Asn Pro Trp Val Ser Leu Leu Gly
                 185                 190                 195

 Ala Val Gly Ser Leu Leu Ile Met Phe Val Ile Gln Trp Val Tyr
                 200                 205                 210

 Thr Leu Val Asn Met Gly Val Ala Ala Ile Val Tyr Phe Tyr Ile
                 215                 220                 225

 Gly Arg Ala Ser Pro Gly Leu His Leu Gly Ser Ala Ser Asn Phe
                 230                 235                 240

 Ser Phe Phe Arg Trp Met Arg Ser Leu Leu Leu Pro Ser Cys Arg
                 245                 250                 255

 Ser Leu Gln Ser Pro Gln Glu Gln Ile Ile Leu Ala Pro Ser Leu
                 260                 265                 270

 Ala Lys Val Asp Met Glu Met Thr Gln Leu Thr Gln Glu Asn Ala
                 275                 280                 285

 Asp Phe Ala Thr Arg Asp Arg Tyr His His Ser Ser Leu Val Asn
                 290                 295                 300

 Arg Glu Gln Leu Met Pro His Tyr
                 305

<210> 3483
<211> 1444
<212> DNA
<213> Homo sapien

<400> 3483
 ggggggggcg gggcgcccag cgggatgcgg tgaagggcga gcggcgcggc 50

 ggctgcgatg agtgcctctg cggccaccgg ggtcttcgtg ctgtccctct 100

 cggccatccc ggtcacctat gtcttcaacc acctggcggc ccagcatgat 150

 tcctggacta ttgtaggggt tgctgccctc atcctgttcc tggtagcact 200

 gctggctcgt gtcctcgtca aaagaaaacc accccgggac ccactgttct 250

 atgtgtatgc agtttttgga tttaccagcg tggtgaacct catcatagga 300

 ctggagcaag atggaatcat tgacgggttc atgacacact acttgagaga 350

 gggtgaaccg tatctgaaca ccgcatatgg gcacatgatc tgctactggg 400

 atggctctgc tcattatctg atgtacctgg tgatggtggc agccatagca 450

 tgggaggaaa cttatagaac cattggccta tattgggttg gatctattat 500

 tatgagtgtt gttgtttttg tgccaggaaa cattgtaggg aagtatggaa 550

 cacgaatttg ccctgctttt ttcttaagca taccatatac ttgtcttcct 600

 gtctgggctg gtttcagaat ctataatcag ccatcagaaa attataatta 650

 cccctcaaag gttattcaag aagcccaagc gaaagacctg ctgagaagac 700

 catttgattt aatgttggtt gtgtgtctcc tcctggcaac tggattttgc 750

 ctgttcagag gtttgattgc tttggattgc ccatctgagc tctgccgatt 800

 atatacgcaa tttcaagagc cctatctaaa ggatcctgct gcttatccta 850

 aaattcagat gctggcatat atgttctatt ctgttcctta ctttgtgact 900

 gcactgtatg gcttagtggt tcctggatgt tcctggatgc ctgacatcac 950

 attgatacat gctggaggtc tggctcaggc tcagttttct cacattggtg 1000

 catctcttca tgctagaact gcttatgtct acagagtccc tgaagaagca 1050

 aaaatccttt ttttagcatt aaacatagta tatggagttc ttcctcagct 1100

 cttggcctat cgttgtatct acaaaccaga gttcttcata aaaacaaagg 1150

 cagaagaaaa agtggaataa aaatattact tcatgttcct cctttctaaa 1200

 ttactaactt ttgttatact ggtactgata ttttgtccca tttcactctc 1250

 ttctcatacg tgagtactta agaatatgta cattcttgct ctgcactgta 1300

 tgtgtgagct atatggtatt gtgtaaattt tttttgaagg aaaatggaaa 1350

 ttcttgagaa acagtttgtt taaagaaata tattcaaaat catttgtgaa 1400

 taaacttgat catccatctc aaaaaaaaaa aaaaaaaaaa aaaa 1444

<210> 3484
<211> 370
<212> PRT
<213> Homo sapien

<400> 3484
 Met Ser Ala Ser Ala Ala Thr Gly Val Phe Val Leu Ser Leu Ser
   1               5                  10                  15

 Ala Ile Pro Val Thr Tyr Val Phe Asn His Leu Ala Ala Gln His
                  20                  25                  30

 Asp Ser Trp Thr Ile Val Gly Val Ala Ala Leu Ile Leu Phe Leu
                  35                  40                  45

 Val Ala Leu Leu Ala Arg Val Leu Val Lys Arg Lys Pro Pro Arg
                  50                  55                  60

 Asp Pro Leu Phe Tyr Val Tyr Ala Val Phe Gly Phe Thr Ser Val
                  65                  70                  75

 Val Asn Leu Ile Ile Gly Leu Glu Gln Asp Gly Ile Ile Asp Gly
                  80                  85                  90

 Phe Met Thr His Tyr Leu Arg Glu Gly Glu Pro Tyr Leu Asn Thr
                  95                 100                 105

 Ala Tyr Gly His Met Ile Cys Tyr Trp Asp Gly Ser Ala His Tyr
                 110                 115                 120

 Leu Met Tyr Leu Val Met Val Ala Ala Ile Ala Trp Glu Glu Thr
                 125                 130                 135

 Tyr Arg Thr Ile Gly Leu Tyr Trp Val Gly Ser Ile Ile Met Ser
                 140                 145                 150

 Val Val Val Phe Val Pro Gly Asn Ile Val Gly Lys Tyr Gly Thr
                 155                 160                 165

 Arg Ile Cys Pro Ala Phe Phe Leu Ser Ile Pro Tyr Thr Cys Leu
                 170                 175                 180

 Pro Val Trp Ala Gly Phe Arg Ile Tyr Asn Gln Pro Ser Glu Asn
                 185                 190                 195

 Tyr Asn Tyr Pro Ser Lys Val Ile Gln Glu Ala Gln Ala Lys Asp
                 200                 205                 210

 Leu Leu Arg Arg Pro Phe Asp Leu Met Leu Val Val Cys Leu Leu
                 215                 220                 225

 Leu Ala Thr Gly Phe Cys Leu Phe Arg Gly Leu Ile Ala Leu Asp
                 230                 235                 240

 Cys Pro Ser Glu Leu Cys Arg Leu Tyr Thr Gln Phe Gln Glu Pro
                 245                 250                 255

 Tyr Leu Lys Asp Pro Ala Ala Tyr Pro Lys Ile Gln Met Leu Ala
                 260                 265                 270

 Tyr Met Phe Tyr Ser Val Pro Tyr Phe Val Thr Ala Leu Tyr Gly
                 275                 280                 285

 Leu Val Val Pro Gly Cys Ser Trp Met Pro Asp Ile Thr Leu Ile
                 290                 295                 300

 His Ala Gly Gly Leu Ala Gln Ala Gln Phe Ser His Ile Gly Ala
                 305                 310                 315

 Ser Leu His Ala Arg Thr Ala Tyr Val Tyr Arg Val Pro Glu Glu
                 320                 325                 330

 Ala Lys Ile Leu Phe Leu Ala Leu Asn Ile Val Tyr Gly Val Leu
                 335                 340                 345

 Pro Gln Leu Leu Ala Tyr Arg Cys Ile Tyr Lys Pro Glu Phe Phe
                 350                 355                 360

 Ile Lys Thr Lys Ala Glu Glu Lys Val Glu
                 365                 370

<210> 3485
<211> 2750
<212> DNA
<213> Homo sapien

<400> 3485
 ggctgccggg gaggccagag cgtggagcgc tgcgcggcgc ggcggccggg 50

 ccctcgagac ggggacggac acaccagccc ctcagatacc acttggccac 100

 tcccgctgag gccactccca ctgcgtggct gaagcctcga ggtcaccagg 150

 cggaggcgcg gagatgcccc tgcatcagct gggggacaag ccgctcacct 200

 tccccagccc caactcagcc atggaaaacg ggcttgacca caccccaccc 250

 agcaggaggg catccccggg cacacccctg agccccggct ccctccgctc 300

 cgctgcccat agccccctgg acaccagcaa gcagcccctc tgccagctct 350

 gggccgagaa gcatggcgcc cgggggaccc atgaggtgcg gtacatctcg 400

 gccgggcaga gcgtggcgtg cggctggtgg gccttcgcac cgccgtgcct 450

 gcaggtcctc aacacgccca agggcatcct gttcttcctg tgtgcggccg 500

 cattcctgca ggggatgact gtgaatggct tcatcaacac agtcatcacc 550

 tccctggagc gccgctatga cctgcacagc taccagagcg ggctcatcgc 600

 cagctcctac gacattgccg cctgcctctg cctcaccttc gtcagctact 650

 tcgggggctc agggcacaag ccgcgctggc tgggctgggg cgtgctgctt 700

 atgggcacgg gttcgctggt gttcgcgctg ccccacttca cggctggccg 750

 ctatgaggtg gagttggacg cgggtgtcag gacgtgccct gccaaccccg 800

 gcgcggtgtg tgcggacagc acctcgggcc tgtcccgcta ccagctggtc 850

 ttcatgctgg gccagttcct gcatggcgtg ggtgccacac ccctctacac 900

 gctgggcgtc acctacctgg atgagaacgt caagtccagc tgctcgcccg 950

 tctacattgc catcttctac acagcggcca tcctgggccc agctgccggc 1000

 tacctgattg gaggtgccct gctgaatatc tacacggaaa tgggccgacg 1050

 gacggagctg accaccgaga gcccactgtg ggtcggcgcc tggtgggtcg 1100

 gcttcctggg ctctggggcc gctgctttct tcaccgccgt tcccatcctt 1150

 ggttaccctc ggcagctgcc aggctcccag cgctacgcgg tcatgagagc 1200

 ggcggaaatg caccagttga aggacagcag ccgtggggag gcgagcaacc 1250

 cggactttgg gaaaaccatc agagacctgc ctctctccat ctggctcctg 1300

 ctgaagaacc ccacgttcat cctgctctgc ctggccgggg ccaccgaggc 1350

 cactctcatc accggcatgt ccacgttcag ccccaagttc ttggagtccc 1400

 agttcagcct gagtgcctca gaagctgcca ccttgtttgg gtacctggtg 1450

 gtgccagcgg gtggtggcgg caccttcctg ggcggcttct ttgtgaacaa 1500

 gctcaggctc cggggctccg cggtcatcaa gttctgcctg ttctgcaccg 1550

 ttgtcagcct gctgggcatc ctcgtcttct cactgcactg ccccagtgtg 1600

 cccatggcgg gcgtcacagc cagctacggc gggagcctcc tgcccgaagg 1650

 ccacctgaac ctaacggctc cctgcaacgc tgcctgcagc tgccagccag 1700

 aacactacag ccctgtgtgc ggctcggacg gcctcatgta cttctcactg 1750

 tgccacgcag ggtgccctgc agccacggag acgaatgtgg acggccagaa 1800

 ggtgtaccga gactgtagct gtatccctca gaatctttcc tctggttttg 1850

 gccatgccac tgcagggaaa tgcacttcaa cttgtcagag aaagcccctc 1900

 cttctggttt tcatattcgt tgtaattttc tttacattcc tcagcagcat 1950

 tcctgcacta acggcaactc tacgatgtgt ccgtgaccct cagagatcct 2000

 ttgccctggg aatccagtgg attgtagtta gaatactagg gggcatcccg 2050

 gggcccatcg ccttcggctg ggtgatcgac aaggcctgtc tgctgtggca 2100

 ggaccagtgt ggccagcagg gctcctgctt ggtgtaccag aattcggcca 2150

 tgagccgcta catactcatc atggggctcc tgtacaaggt gctgggcgtc 2200

 ctcttctttg ccatagcctg cttcttatac aagcccctgt cggagtcttc 2250

 agatggcctg gaaacttgtc tgcccagcca gtcctcagcc cctgacagtg 2300

 ccacagatag ccagctccag agcagcgtct gaccaccgcc cgcgcccacc 2350

 cggccacggc gggcactcag catttcctga tgacagaaca gtgccgttgg 2400

 gtgatgcaat cacacgggaa cttctatttg acctgcaacc ttctacttaa 2450

 cctgtggttt aaagtcggct gtgacctcct gtccccagag ctgtacggcc 2500

 ctgcagtggg tgggaggaac ttgcataaat atatatttat ggacacacag 2550

 tttgcatcag aacgtgttta tagaatgtgt tttatacccg atcgtgtgtg 2600

 gtgtgcgtga ggacaaactc cgcaggggct gtgaatccca ctgggagggc 2650

 ggcgggcctg cagcccgagg aaggcttgtg tgtcctcagt taaaactgtg 2700

 catatcgaaa tatattttgt tatttaagcc tgaaaaaaaa aaaaaaaaaa 2750

<210> 3486
<211> 722
<212> PRT
<213> Homo sapien

<400> 3486
 Met Pro Leu His Gln Leu Gly Asp Lys Pro Leu Thr Phe Pro Ser
   1               5                  10                  15

 Pro Asn Ser Ala Met Glu Asn Gly Leu Asp His Thr Pro Pro Ser
                  20                  25                  30

 Arg Arg Ala Ser Pro Gly Thr Pro Leu Ser Pro Gly Ser Leu Arg
                  35                  40                  45

 Ser Ala Ala His Ser Pro Leu Asp Thr Ser Lys Gln Pro Leu Cys
                  50                  55                  60

 Gln Leu Trp Ala Glu Lys His Gly Ala Arg Gly Thr His Glu Val
                  65                  70                  75

 Arg Tyr Ile Ser Ala Gly Gln Ser Val Ala Cys Gly Trp Trp Ala
                  80                  85                  90

 Phe Ala Pro Pro Cys Leu Gln Val Leu Asn Thr Pro Lys Gly Ile
                  95                 100                 105

 Leu Phe Phe Leu Cys Ala Ala Ala Phe Leu Gln Gly Met Thr Val
                 110                 115                 120

 Asn Gly Phe Ile Asn Thr Val Ile Thr Ser Leu Glu Arg Arg Tyr
                 125                 130                 135

 Asp Leu His Ser Tyr Gln Ser Gly Leu Ile Ala Ser Ser Tyr Asp
                 140                 145                 150

 Ile Ala Ala Cys Leu Cys Leu Thr Phe Val Ser Tyr Phe Gly Gly
                 155                 160                 165

 Ser Gly His Lys Pro Arg Trp Leu Gly Trp Gly Val Leu Leu Met
                 170                 175                 180

 Gly Thr Gly Ser Leu Val Phe Ala Leu Pro His Phe Thr Ala Gly
                 185                 190                 195

 Arg Tyr Glu Val Glu Leu Asp Ala Gly Val Arg Thr Cys Pro Ala
                 200                 205                 210

 Asn Pro Gly Ala Val Cys Ala Asp Ser Thr Ser Gly Leu Ser Arg
                 215                 220                 225

 Tyr Gln Leu Val Phe Met Leu Gly Gln Phe Leu His Gly Val Gly
                 230                 235                 240

 Ala Thr Pro Leu Tyr Thr Leu Gly Val Thr Tyr Leu Asp Glu Asn
                 245                 250                 255

 Val Lys Ser Ser Cys Ser Pro Val Tyr Ile Ala Ile Phe Tyr Thr
                 260                 265                 270

 Ala Ala Ile Leu Gly Pro Ala Ala Gly Tyr Leu Ile Gly Gly Ala
                 275                 280                 285

 Leu Leu Asn Ile Tyr Thr Glu Met Gly Arg Arg Thr Glu Leu Thr
                 290                 295                 300

 Thr Glu Ser Pro Leu Trp Val Gly Ala Trp Trp Val Gly Phe Leu
                 305                 310                 315

 Gly Ser Gly Ala Ala Ala Phe Phe Thr Ala Val Pro Ile Leu Gly
                 320                 325                 330

 Tyr Pro Arg Gln Leu Pro Gly Ser Gln Arg Tyr Ala Val Met Arg
                 335                 340                 345

 Ala Ala Glu Met His Gln Leu Lys Asp Ser Ser Arg Gly Glu Ala
                 350                 355                 360

 Ser Asn Pro Asp Phe Gly Lys Thr Ile Arg Asp Leu Pro Leu Ser
                 365                 370                 375

 Ile Trp Leu Leu Leu Lys Asn Pro Thr Phe Ile Leu Leu Cys Leu
                 380                 385                 390

 Ala Gly Ala Thr Glu Ala Thr Leu Ile Thr Gly Met Ser Thr Phe
                 395                 400                 405

 Ser Pro Lys Phe Leu Glu Ser Gln Phe Ser Leu Ser Ala Ser Glu
                 410                 415                 420

 Ala Ala Thr Leu Phe Gly Tyr Leu Val Val Pro Ala Gly Gly Gly
                 425                 430                 435

 Gly Thr Phe Leu Gly Gly Phe Phe Val Asn Lys Leu Arg Leu Arg
                 440                 445                 450

 Gly Ser Ala Val Ile Lys Phe Cys Leu Phe Cys Thr Val Val Ser
                 455                 460                 465

 Leu Leu Gly Ile Leu Val Phe Ser Leu His Cys Pro Ser Val Pro
                 470                 475                 480

 Met Ala Gly Val Thr Ala Ser Tyr Gly Gly Ser Leu Leu Pro Glu
                 485                 490                 495

 Gly His Leu Asn Leu Thr Ala Pro Cys Asn Ala Ala Cys Ser Cys
                 500                 505                 510

 Gln Pro Glu His Tyr Ser Pro Val Cys Gly Ser Asp Gly Leu Met
                 515                 520                 525

 Tyr Phe Ser Leu Cys His Ala Gly Cys Pro Ala Ala Thr Glu Thr
                 530                 535                 540

 Asn Val Asp Gly Gln Lys Val Tyr Arg Asp Cys Ser Cys Ile Pro
                 545                 550                 555

 Gln Asn Leu Ser Ser Gly Phe Gly His Ala Thr Ala Gly Lys Cys
                 560                 565                 570

 Thr Ser Thr Cys Gln Arg Lys Pro Leu Leu Leu Val Phe Ile Phe
                 575                 580                 585

 Val Val Ile Phe Phe Thr Phe Leu Ser Ser Ile Pro Ala Leu Thr
                 590                 595                 600

 Ala Thr Leu Arg Cys Val Arg Asp Pro Gln Arg Ser Phe Ala Leu
                 605                 610                 615

 Gly Ile Gln Trp Ile Val Val Arg Ile Leu Gly Gly Ile Pro Gly
                 620                 625                 630

 Pro Ile Ala Phe Gly Trp Val Ile Asp Lys Ala Cys Leu Leu Trp
                 635                 640                 645

 Gln Asp Gln Cys Gly Gln Gln Gly Ser Cys Leu Val Tyr Gln Asn
                 650                 655                 660

 Ser Ala Met Ser Arg Tyr Ile Leu Ile Met Gly Leu Leu Tyr Lys
                 665                 670                 675

 Val Leu Gly Val Leu Phe Phe Ala Ile Ala Cys Phe Leu Tyr Lys
                 680                 685                 690

 Pro Leu Ser Glu Ser Ser Asp Gly Leu Glu Thr Cys Leu Pro Ser
                 695                 700                 705

 Gln Ser Ser Ala Pro Asp Ser Ala Thr Asp Ser Gln Leu Gln Ser
                 710                 715                 720

 Ser Val


<210> 3487
<211> 10434
<212> DNA
<213> Homo sapien

<400> 3487
 atggcgaacc ggcgagtggg gcgaggctgc tgggaagtga gcccgaccga 50

 gcggaggccg cccgcggggc tgcggggccc cgcggccgag gaggaggcgt 100

 cttccccgcc ggtcctgtct ctcagccact tctgcaggtc tcctttcctt 150

 tgcttcgggg acgttctcct gggagcctca cggacgctgt ctctggccct 200

 agacaaccct aacgaggagg tggcagaagt gaagatctcc cacttcccgg 250

 ccgcggacct gggcttcagt gtgtcgcagc gctgtttcgt gttgcagcct 300

 aaagagaaaa ttgttatttc tgttaactgg acaccactca aagaaggccg 350

 agtaagagag attatgacat ttcttgtaaa tgatgttctg aaacaccaag 400

 ctatattact aggaaatgca gaagagcaga aaaagaaaaa gaggagtctt 450

 tgggatacca ttaaaaagaa gaaaatttca gcctctacaa gtcacaacag 500

 aagggtttca aatattcaga atgttaataa aacatttagt gtttcccaaa 550

 aagttgacag agttaggagc ccactacaag cttgtgaaaa cttggctatg 600

 aatgaaggcg gtcccccaac agaaaacaat tctttaatac ttgaagaaaa 650

 taaaataccc atatcaccta ttagccctgc tttcaatgaa tgccatggtg 700

 caacttgctt gccactctct gtacgtcgat ctactaccta ctcatctctt 750

 catgcatcag aaaataggga actattaaat gtacacagtg ccaacgtttc 800

 aaaagtttct tttaatgaga aagctgtaac tgaaacttcc tttaattctg 850

 taaatgttaa tggccaaaga ggagagaata gtaaacttag tcttaccccc 900

 aactgttctt caactttgaa cattacacaa agccaaatac attttctaag 950

 tccagattct tttgtaaata atagtcatgg agctaataat gaactagaat 1000

 tagtaacatg tctttcatca gatatgttta tgaaagataa ttcacagcct 1050

 gtgcatttgg aatcaacaat tgcacatgaa atttatcaga aaattttaag 1100

 tccagattct ttcataaaag ataattatgg actaaatcag gatctagaat 1150

 cagagtcagt taatcctatt ttatccccta atcaattttt aaaagataac 1200

 atggcatata tgtgtacatc tcagcaaaca tgtaaagtac cattatcaaa 1250

 tgaaaattct caagtcccac agtctcctga agattggaga aaaagtgaag 1300

 tttcgccacg tattcctgaa tgtcagggtt caaaatctcc caaagctatt 1350

 tttgaagaac tagtagaaat gaagtcaaat tactacagtt ttataaaaca 1400

 aaataatcct aaattttctg cagttcagga tatttctagt catagccaca 1450

 ataaacaacc taagagacgt ccaatacttt ctgccactgt tactaaaagg 1500

 aaggccacct gtaccagaga aaaccaaact gagattaata aaccaaaagc 1550

 aaaaagatgt ctcaacagtg cagtgggtga acatgaaaaa gtaataaata 1600

 atcaaaagga aaaagaagat tttcattctt atcttccaat tatagatcca 1650

 atattaagta aatctaagag ttataaaaac gaggtaacac cctcttcgac 1700

 aacagcttca gttgctcgga aaagaaagag cgatggaagc atggaagatg 1750

 caaatgtgag agttgcaatt acagaacata cagaagtgcg agaaatcaaa 1800

 agaatccatt tttctccctc agagcctaaa acatcagctg ttaagaaaac 1850

 aaaaaatgtg acaacaccca tctcaaaacg tattagcaac agagagaaat 1900

 taaacctgaa gaagaaaact gatttatcaa tattcagaac tccaatttct 1950

 aaaacaaaca aaaggacaaa acccattatc gctgtggcac agtccagttt 2000

 gaccttcata aaaccattaa aaacagatat tcccagacac ccgatgccat 2050

 ttgctgcaaa aaacatgttt tatgatgaac gctggaagga aaagcaggaa 2100

 cagggcttca cttggtggtt aaattttata ttaacccctg atgacttcac 2150

 tgtaaaaaca aatatttctg aagtaaatgc tgctactctt cttttgggaa 2200

 tagagaatca acataaaata agtgttccta gagcacctac aaaagaggaa 2250

 atgtctctca gagcttatac tgctcggtgt aggttaaaca gactacgtcg 2300

 tgcagcatgc cgtttgttta cttctgaaaa aatggttaaa gctattaaaa 2350

 agcttgaaat tgaaattgaa gctaggcggt taattgttcg aaaagataga 2400

 cacctatgga aagatgtggg agaacgtcag aaagtcctga attggctgtt 2450

 gtcctacaat cctttgtggc ttcgaattgg tctagagaca acttatggag 2500

 aactcatatc tttggaagat aacagtgatg tcacagggtt ggctatgttt 2550

 attctgaatc gcctactttg gaatcctgat atagcagctg agtatagaca 2600

 ccccactgtt cctcacctgt atagagatgg tcatgaagaa gctttgtcca 2650

 agtttacatt gaaaaagtta ttgttgttgg tctgttttct tgattatgct 2700

 aaaatttcca gactcattga tcatgatcct tgtctcttct gtaaagatgc 2750

 cgaattcaag gctagtaaag aaatcctttt ggctttttca cgagatttcc 2800

 taagtggtga aggtgacctt tcccgtcacc ttggcttatt gggattacct 2850

 gttaaccatg ttcagacacc atttgatgaa tttgattttg ccgttacaaa 2900

 tcttgccgta gacttgcaat gtggagtgcg ccttgtgcga accatggaac 2950

 ttctcacaca gaactgggac ctctcaaaga aactcaggat tccggcaata 3000

 agtcgtcttc aaaagatgca caatgttgac attgttcttc aagttcttaa 3050

 atcacgagga attgaattaa gtgatgagca tggaaataca attctatcta 3100

 aggatattgt ggataggcac agagaaaaaa ctctcaggtt gctttggaaa 3150

 atagcgtttg cttttcaggt ggatatttcc cttaacttag atcaattaaa 3200

 ggaagaaatt gcctttctaa aacacacaaa gagtataaag aaaacaatat 3250

 ctctactatc atgccattct gatgatctta ttaataagaa aaaaggcaaa 3300

 agggatagtg gttcctttga acaatatagt gaaaacataa agttattgat 3350

 ggattgggta aatgctgttt gtgccttcta taataaaaag gtggagaatt 3400

 ttacagtgtc tttctcagac ggccgtgtgt tatgttacct gatccaccat 3450

 taccatcctt gctatgtgcc atttgacgct atatgtcagc gtactactca 3500

 aactgtggaa tgtacgcaaa ctggttcagt ggtattaaat tcatcatctg 3550

 aatctgatga cagttctctg gatatgtcac ttaaagcatt tgatcatgaa 3600

 aatacttcag agctatacaa agagctccta gaaaatgaaa agaaaaattt 3650

 tcacttggtt aggtctgcag ttagagacct tggtggaata cctgctatga 3700

 ttaatcattc agatatgtca aatacaattc cagatgaaaa ggtggttatt 3750

 acctatttgt catttctttg tgcaaggctt ttggatcttc gtaaagaaat 3800

 aagagctgct cgactcatac aaacaacatg gagaaaatat aaactaaaaa 3850

 cagatctcaa acgccatcag gagagagaga aagctgcaag aattattcaa 3900

 ttggctgtaa tcaattttct agcaaaacaa agattgagaa aaagagttaa 3950

 tgcagcactc gtcattcaga aatattggcg aagagtctta gcacagagaa 4000

 aattattaat gttaaaaaag gaaaagctgg aaaaagttca aaataaagca 4050

 gcatcactta ttcagggata ttggagaaga tattccacta gacaaagatt 4100

 tctgaaattg aaatattatt caatcatcct gcaatctagg ataagaatga 4150

 taattgctgt tacatcttat aaacgatatc tttgggctac agttacaatt 4200

 cagaggcatt ggcgtgctta tttaagaaga aaacaagatc aacaaagata 4250

 tgaaatgcta aaatcatcaa ctcttataat ccaatctatg ttcagaaaat 4300

 ggaagcaacg taaaatgcaa tcacaagtaa aagctacagt aatattgcaa 4350

 agagctttta gagaatggca tttaagaaaa caagctaaag aagaaaattc 4400

 tgctattatc atacaatcat ggtatagaat gcataaagaa ttacggaagt 4450

 atatttatat tagatcttgt gttgttatca ttcagaaaag atttcggtgc 4500

 tttcaagccc aaaagttata taaaagaaga aaagagtcca tactaaccat 4550

 ccagaagtac tacaaagcat atctgaaagg aaagattgag cgcaccaact 4600

 atttgcagaa acgagctgca gccattcaat tacaagctgc ttttaggaga 4650

 ctgaaagctc ataatttatg tagacaaatt agagctgctt gtgttattca 4700

 gtcatactgg agaatgagac aagacagagt tcgattttta aaccttaaga 4750

 agactattat caaatttcag gcacatgtaa gaaaacatca acaacgacag 4800

 aaatataaga agatgaagaa agcagctgtt ataattcaga ctcatttccg 4850

 agcttatatt tttgccatga aagttctagc atcttaccag aaaacacgct 4900

 ctgctgtcat tgtgctgcag tctgcatata gagggatgca agccaggaaa 4950

 atgtatattc acatcctcac atctgttata aagattcaat catattatcg 5000

 tgcttatgtt tctaaaaagg aatttttgag cctaaaaaat gctacaataa 5050

 aattgcagtc aactgttaag atgaaacaaa cacgtaaaca atatttgcat 5100

 ttaagagcag ctgcactatt tatccagcaa tgttaccgtt ccaaaaaaat 5150

 agctgcacaa aagagagaag agtatatgca gatgcgggaa tcttgtatca 5200

 aactgcaagc atttgttaga ggataccttg tccgaaagca gatgaggtta 5250

 caaagaaaag ctgttatttc actacagtct tatttcagaa tgagaaaggc 5300

 tcggcagtat tatctgaaaa tgtataaagc aattattgtc attcagaatt 5350

 actatcatgc atacaaagca caggtcaatc agaggaagaa cttcttgcaa 5400

 gtcaaaaaag cagctacttg cttgcaagca gcttacagag gttataaagt 5450

 acgccagcta atcaaacaac aatctatagc tgctcttaaa attcagtctg 5500

 cttttagagg ctataataaa agggtaaaat atcaatctgt gcttcaatct 5550

 ataataaaga ttcagagatg gtacagggcg tacaagactc ttcatgatac 5600

 aagaacacat tttttgaaga caaaggcagc tgtgatttcc ctccagtctg 5650

 cttatcgtgg ctggaaggtt cggaaacaga ttagaaggga acatcaagct 5700

 gccttgaaga ttcagtctgc ttttagaatg gccaaggccc agaaacagtt 5750

 tagattgttt aaaacagcag cattagtcat ccagcaaaat ttcagagcat 5800

 ggactgcagg aaggaagcaa tgtatggagt atattgaact ccgtcatgcg 5850

 gtactggtgc ttcaatctat gtggaaggga aaaacactga gaagacagct 5900

 tcaaaggcaa cataaatgtg ctatcatcat acagtcatac tatagaatgc 5950

 atgtgcaaca aaagaagtgg aaaatcatga aaaaagctgc tcttctgatt 6000

 caaaagtatt atagggctta cagtattgga agagaacaga atcatttata 6050

 tttgaaaaca aaagcagctg tagtaacttt acagtcagct tatcgtggta 6100

 tgaaagtgag aaaaagaata aaggattgca acaaagcagc agtcactata 6150

 cagtctaaat acagagctta caaaaccaaa aagaaatatg caacctatag 6200

 agcttcagct attataattc agagatggta tcgaggtatt aaaattacaa 6250

 accatcagca taaggagtat cttaatttga agaagacagc aattaaaatc 6300

 caatctgttt atagaggtat tagagttaga agacatattc aacacatgca 6350

 cagggcagcc acttttatta aagccatgtt taaaatgcat cagtcaagaa 6400

 taagttacca tacaatgaga aaagcagcta ttgttattca agtaagatgt 6450

 agagcatatt atcaaggtaa aatgcagcgt gaaaagtacc tgacaatttt 6500

 gaaagctgtt aaagtccttc aggcaagttt tagaggagta agagttagac 6550

 ggactcttag aaagatgcag actgcagcaa cactcattca gtcaaactac 6600

 agaagataca gacagcaaac atactttaat aagttaaaga aaataacaaa 6650

 aacagtacag caaagatact gggcaatgaa agaaagaaac atacaatttc 6700

 aaaggtataa caaactgagg cattctgtaa tatacattca ggctattttt 6750

 aggggaaaga aagctagaag acatttaaaa atgatgcata tagccgcaac 6800

 tctcattcag aggagattta gaactctaat gatgagaaga agattcctct 6850

 ctctcaagaa aactgctatt ttgattcaga gaaaatatcg ggcacatctt 6900

 tgtacaaagc atcacttaca gttccttcag gtacaaaatg cagttattaa 6950

 aatccagtca tcatacagaa gatggatgat aaggaaaagg atgcgagaga 7000

 tgcacagggc tgctactttc atccagtcta ctttcagaat gcacagatta 7050

 catatgagat atcgagcttt gaaacaggcc tccgttgtga tccaacagca 7100

 ataccaagca aatagagctg caaaactgca gaggcagcat tatctcagac 7150

 aaagacactc tgctgtgatc cttcaggctg cattcagggg tatgaaaact 7200

 agaagacatt tgaagagtat gcattcctct gcaaccctta ttcagagtag 7250

 gtttagatca ttactggtga ggagaagatt catttccctc aaaaaagcta 7300

 ctatttttgt tcagaggaaa tatcgagcca ccatttgtgc caaacataaa 7350

 ttgtaccaat tcttgcactt aagaaaggca gccattacaa tacagtcatc 7400

 ttacagaaga ctgatggtaa agaagaagtt acaagaaatg caaagggctg 7450

 cagttctcat tcaggctact ttcaggatgc acagaacata tattacattt 7500

 cagacttgga aacatgcttc aattctaatt cagcaacatt atcgaacata 7550

 tagagctgca aaattgcaaa gagaaaatta tatcagacaa tggcattctg 7600

 ctgtggttat tcaggctgca tataaaggaa tgaaagcaag acaactttta 7650

 agggaaaaac acaaagcttc tatcgtaata caaagcacct acagaatgta 7700

 taggcagtat tgtttctacc aaaagcttca gtgggctaca aaaatcatac 7750

 aagaaaaata tagagcaaat aaaaagaaac agaaagtatt tcaacacaat 7800

 gaacttaaga aagagacttg tgttcaggca ggttttcagg acatgaacat 7850

 aaaaaaacag attcaggaac agcaccaggc tgccattatt attcagaagc 7900

 attgtaaagc ctttaaaata aggaagcatt atctccacct tagagcaaca 7950

 gtagtttcta ttcaaagaag atacagaaaa ctaactgcag tgcgtaccca 8000

 agcagttatt tgtatacagt cttattacag aggctttaaa gtacgaaagg 8050

 atattcaaaa tatgcaccgg gctgccacac taattcagtc attctatcga 8100

 atgcacaggg ccaaagttga ttatgaaaca aagaaaactg caattgtggt 8150

 tatacagaat tattataggt tgtatgttag agtaaaaaca gaaagaaaaa 8200

 actttttagc agttcagaaa tctgtacgaa ctattcaggc tgcttttaga 8250

 ggcatgaaag ttagacaaaa attgaaaaat gtatcagagg aaaagatggc 8300

 agccattgtt aaccaatctg cactctgctg ttacagaagt aaaactcagt 8350

 atgaagctgt tcaaagtgaa ggtgttatga ttcaagagtg gtataaagct 8400

 tctggccttg cttgttcaca ggaagcagag tatcattctc aaagtagggc 8450

 tgcagtaaca attcaaaaag ctttttgtag aatggtcaca agaaaactgg 8500

 aaacacagaa atgtgctgcc ctacggattc agttcttcct tcagatggct 8550

 gtgtatcgga gaagatttgt tcagcagaaa agagctgcta tcactttaca 8600

 gcattatttt aggacgtggc aaaccagaaa acagttttta ctatatagaa 8650

 aagcagcagt ggttttacaa aatcactaca gagcatttct gtctgcaaaa 8700

 catcaaagac aagtctattt acagatcaga agcagtgtta tcattattca 8750

 agctagaagt aaaggattta tacagaaacg gaagtttcag gaaattaaaa 8800

 atagcaccat aaaaattcag gctatgtgga ggagatatag agccaagaaa 8850

 tatttatgta aagtgaaagc tgcctgcaag attcaagcct ggtatagatg 8900

 ttggagagca cacaaagaat atctagctat attaaaagct gttaaaatta 8950

 ttcaaggttg cttctatacc aaactagaga gaacacggtt tttgaatgtg 9000

 agagcatcag caattatcat tcagagaaaa tggagagcta tacttcctgc 9050

 aaagatagct catgaacact tcttaatgat aaaaagacat cgagctgctt 9100

 gtttgatcca agcacattat agaggatata aaggaaggca ggtctttctt 9150

 cggcagaaat ctgctgcttt gatcatacaa aaatatatac gagccaggga 9200

 ggctggaaag catgaaagga taaaatatat tgaatttaaa aaatctacag 9250

 ttatcctaca agcactggtg cgtggttggc tagtacgaaa aagattttta 9300

 gaacagagag ccaaaattcg acttcttcac ttcactgcag ctgcatatta 9350

 tcacctgaat gctgttagaa ttcaaagagc ctataaactt tacctggctg 9400

 tgaagaatgc taacaagcag gttaattcag tcatctgtat tcagagatgg 9450

 tttcgagcaa gattacaaga aaagagattt attcagaaat atcatagcat 9500

 caaaaagatt gagcatgaag gtcaagaatg tctgagccag cgaaataggg 9550

 ctgcatcagt aatacagaaa gcagtgcgcc attttctcct ccgtaaaaag 9600

 caggaaaaat tcactagtgg aatcattaaa attcaggcat tatggagagg 9650

 ctattcttgg aggaagaaaa atgattgtac aaaaattaaa gctatacgac 9700

 taagtcttca agttgttaat agggagattc gagaagaaaa caaactctac 9750

 aaaagaactg cacttgcact tcattacctt ttgacatata agcacctttc 9800

 tgccattctt gaggccttaa aacacctaga ggtagttact agattgtctc 9850

 cactttgttg tgagaacatg gcccagagtg gagcaatttc taaaatattt 9900

 gttttgatcc gaagttgtaa tcgcagtatt ccttgtatgg aagtcatcag 9950

 atatgctgtg caagtcttgc ttaatgtatc taagtatgag aaaactactt 10000

 cagcagttta tgatgtagaa aattgtatag atatactatt ggagcttttg 10050

 cagatatacc gagaaaagcc tggtaataaa gttgcagaca aaggcggaag 10100

 catttttaca aaaacttgtt gtttgttggc tattttactg aagacaacaa 10150

 atagagcctc tgatgtacga agtaggtcca aagttgttga ccgtatttac 10200

 agtctctaca aacttacagc tcataaacat aaaatgaata ctgaaagaat 10250

 actttacaag caaaagaaga attcttctat aagcattcct tttatcccag 10300

 aaacacctgt aaggaccaga atagtttcaa gacttaagcc agattgggtt 10350

 ttgagaagag ataacatgga agaaatcaca aatcccctgc aagctattca 10400

 aatggtgatg gatacgcttg gcattcctta ttag 10434

<210> 3488
<211> 2000
<212> PRT
<213> Homo sapien

<400> 3488
 Met Ala Asn Arg Arg Val Gly Arg Gly Cys Trp Glu Val Ser Pro
   1               5                  10                  15

 Thr Glu Arg Arg Pro Pro Ala Gly Leu Arg Gly Pro Ala Ala Glu
                  20                  25                  30

 Glu Glu Ala Ser Ser Pro Pro Val Leu Ser Leu Ser His Phe Cys
                  35                  40                  45

 Arg Ser Pro Phe Leu Cys Phe Gly Asp Val Leu Leu Gly Ala Ser
                  50                  55                  60

 Arg Thr Leu Ser Leu Ala Leu Asp Asn Pro Asn Glu Glu Val Ala
                  65                  70                  75

 Glu Val Lys Ile Ser His Phe Pro Ala Ala Asp Leu Gly Phe Ser
                  80                  85                  90

 Val Ser Gln Arg Cys Phe Val Leu Gln Pro Lys Glu Lys Ile Val
                  95                 100                 105

 Ile Ser Val Asn Trp Thr Pro Leu Lys Glu Gly Arg Val Arg Glu
                 110                 115                 120

 Ile Met Thr Phe Leu Val Asn Asp Val Leu Lys His Gln Ala Ile
                 125                 130                 135

 Leu Leu Gly Asn Ala Glu Glu Gln Lys Lys Lys Lys Arg Ser Leu
                 140                 145                 150

 Trp Asp Thr Ile Lys Lys Lys Lys Ile Ser Ala Ser Thr Ser His
                 155                 160                 165

 Asn Arg Arg Val Ser Asn Ile Gln Asn Val Asn Lys Thr Phe Ser
                 170                 175                 180

 Val Ser Gln Lys Val Asp Arg Val Arg Ser Pro Leu Gln Ala Cys
                 185                 190                 195

 Glu Asn Leu Ala Met Asn Glu Gly Gly Pro Pro Thr Glu Asn Asn
                 200                 205                 210

 Ser Leu Ile Leu Glu Glu Asn Lys Ile Pro Ile Ser Pro Ile Ser
                 215                 220                 225

 Pro Ala Phe Asn Glu Cys His Gly Ala Thr Cys Leu Pro Leu Ser
                 230                 235                 240

 Val Arg Arg Ser Thr Thr Tyr Ser Ser Leu His Ala Ser Glu Asn
                 245                 250                 255

 Arg Glu Leu Leu Asn Val His Ser Ala Asn Val Ser Lys Val Ser
                 260                 265                 270

 Phe Asn Glu Lys Ala Val Thr Glu Thr Ser Phe Asn Ser Val Asn
                 275                 280                 285

 Val Asn Gly Gln Arg Gly Glu Asn Ser Lys Leu Ser Leu Thr Pro
                 290                 295                 300

 Asn Cys Ser Ser Thr Leu Asn Ile Thr Gln Ser Gln Ile His Phe
                 305                 310                 315

 Leu Ser Pro Asp Ser Phe Val Asn Asn Ser His Gly Ala Asn Asn
                 320                 325                 330

 Glu Leu Glu Leu Val Thr Cys Leu Ser Ser Asp Met Phe Met Lys
                 335                 340                 345

 Asp Asn Ser Gln Pro Val His Leu Glu Ser Thr Ile Ala His Glu
                 350                 355                 360

 Ile Tyr Gln Lys Ile Leu Ser Pro Asp Ser Phe Ile Lys Asp Asn
                 365                 370                 375

 Tyr Gly Leu Asn Gln Asp Leu Glu Ser Glu Ser Val Asn Pro Ile
                 380                 385                 390

 Leu Ser Pro Asn Gln Phe Leu Lys Asp Asn Met Ala Tyr Met Cys
                 395                 400                 405

 Thr Ser Gln Gln Thr Cys Lys Val Pro Leu Ser Asn Glu Asn Ser
                 410                 415                 420

 Gln Val Pro Gln Ser Pro Glu Asp Trp Arg Lys Ser Glu Val Ser
                 425                 430                 435

 Pro Arg Ile Pro Glu Cys Gln Gly Ser Lys Ser Pro Lys Ala Ile
                 440                 445                 450

 Phe Glu Glu Leu Val Glu Met Lys Ser Asn Tyr Tyr Ser Phe Ile
                 455                 460                 465

 Lys Gln Asn Asn Pro Lys Phe Ser Ala Val Gln Asp Ile Ser Ser
                 470                 475                 480

 His Ser His Asn Lys Gln Pro Lys Arg Arg Pro Ile Leu Ser Ala
                 485                 490                 495

 Thr Val Thr Lys Arg Lys Ala Thr Cys Thr Arg Glu Asn Gln Thr
                 500                 505                 510

 Glu Ile Asn Lys Pro Lys Ala Lys Arg Cys Leu Asn Ser Ala Val
                 515                 520                 525

 Gly Glu His Glu Lys Val Ile Asn Asn Gln Lys Glu Lys Glu Asp
                 530                 535                 540

 Phe His Ser Tyr Leu Pro Ile Ile Asp Pro Ile Leu Ser Lys Ser
                 545                 550                 555

 Lys Ser Tyr Lys Asn Glu Val Thr Pro Ser Ser Thr Thr Ala Ser
                 560                 565                 570

 Val Ala Arg Lys Arg Lys Ser Asp Gly Ser Met Glu Asp Ala Asn
                 575                 580                 585

 Val Arg Val Ala Ile Thr Glu His Thr Glu Val Arg Glu Ile Lys
                 590                 595                 600

 Arg Ile His Phe Ser Pro Ser Glu Pro Lys Thr Ser Ala Val Lys
                 605                 610                 615

 Lys Thr Lys Asn Val Thr Thr Pro Ile Ser Lys Arg Ile Ser Asn
                 620                 625                 630

 Arg Glu Lys Leu Asn Leu Lys Lys Lys Thr Asp Leu Ser Ile Phe
                 635                 640                 645

 Arg Thr Pro Ile Ser Lys Thr Asn Lys Arg Thr Lys Pro Ile Ile
                 650                 655                 660

 Ala Val Ala Gln Ser Ser Leu Thr Phe Ile Lys Pro Leu Lys Thr
                 665                 670                 675

 Asp Ile Pro Arg His Pro Met Pro Phe Ala Ala Lys Asn Met Phe
                 680                 685                 690

 Tyr Asp Glu Arg Trp Lys Glu Lys Gln Glu Gln Gly Phe Thr Trp
                 695                 700                 705

 Trp Leu Asn Phe Ile Leu Thr Pro Asp Asp Phe Thr Val Lys Thr
                 710                 715                 720

 Asn Ile Ser Glu Val Asn Ala Ala Thr Leu Leu Leu Gly Ile Glu
                 725                 730                 735

 Asn Gln His Lys Ile Ser Val Pro Arg Ala Pro Thr Lys Glu Glu
                 740                 745                 750

 Met Ser Leu Arg Ala Tyr Thr Ala Arg Cys Arg Leu Asn Arg Leu
                 755                 760                 765

 Arg Arg Ala Ala Cys Arg Leu Phe Thr Ser Glu Lys Met Val Lys
                 770                 775                 780

 Ala Ile Lys Lys Leu Glu Ile Glu Ile Glu Ala Arg Arg Leu Ile
                 785                 790                 795

 Val Arg Lys Asp Arg His Leu Trp Lys Asp Val Gly Glu Arg Gln
                 800                 805                 810

 Lys Val Leu Asn Trp Leu Leu Ser Tyr Asn Pro Leu Trp Leu Arg
                 815                 820                 825

 Ile Gly Leu Glu Thr Thr Tyr Gly Glu Leu Ile Ser Leu Glu Asp
                 830                 835                 840

 Asn Ser Asp Val Thr Gly Leu Ala Met Phe Ile Leu Asn Arg Leu
                 845                 850                 855

 Leu Trp Asn Pro Asp Ile Ala Ala Glu Tyr Arg His Pro Thr Val
                 860                 865                 870

 Pro His Leu Tyr Arg Asp Gly His Glu Glu Ala Leu Ser Lys Phe
                 875                 880                 885

 Thr Leu Lys Lys Leu Leu Leu Leu Val Cys Phe Leu Asp Tyr Ala
                 890                 895                 900

 Lys Ile Ser Arg Leu Ile Asp His Asp Pro Cys Leu Phe Cys Lys
                 905                 910                 915

 Asp Ala Glu Phe Lys Ala Ser Lys Glu Ile Leu Leu Ala Phe Ser
                 920                 925                 930

 Arg Asp Phe Leu Ser Gly Glu Gly Asp Leu Ser Arg His Leu Gly
                 935                 940                 945

 Leu Leu Gly Leu Pro Val Asn His Val Gln Thr Pro Phe Asp Glu
                 950                 955                 960

 Phe Asp Phe Ala Val Thr Asn Leu Ala Val Asp Leu Gln Cys Gly
                 965                 970                 975

 Val Arg Leu Val Arg Thr Met Glu Leu Leu Thr Gln Asn Trp Asp
                 980                 985                 990

 Leu Ser Lys Lys Leu Arg Ile Pro Ala Ile Ser Arg Leu Gln Lys
                 995                1000                1005

 Met His Asn Val Asp Ile Val Leu Gln Val Leu Lys Ser Arg Gly
                1010                1015                1020

 Ile Glu Leu Ser Asp Glu His Gly Asn Thr Ile Leu Ser Lys Asp
                1025                1030                1035

 Ile Val Asp Arg His Arg Glu Lys Thr Leu Arg Leu Leu Trp Lys
                1040                1045                1050

 Ile Ala Phe Ala Phe Gln Val Asp Ile Ser Leu Asn Leu Asp Gln
                1055                1060                1065

 Leu Lys Glu Glu Ile Ala Phe Leu Lys His Thr Lys Ser Ile Lys
                1070                1075                1080

 Lys Thr Ile Ser Leu Leu Ser Cys His Ser Asp Asp Leu Ile Asn
                1085                1090                1095

 Lys Lys Lys Gly Lys Arg Asp Ser Gly Ser Phe Glu Gln Tyr Ser
                1100                1105                1110

 Glu Asn Ile Lys Leu Leu Met Asp Trp Val Asn Ala Val Cys Ala
                1115                1120                1125

 Phe Tyr Asn Lys Lys Val Glu Asn Phe Thr Val Ser Phe Ser Asp
                1130                1135                1140

 Gly Arg Val Leu Cys Tyr Leu Ile His His Tyr His Pro Cys Tyr
                1145                1150                1155

 Val Pro Phe Asp Ala Ile Cys Gln Arg Thr Thr Gln Thr Val Glu
                1160                1165                1170

 Cys Thr Gln Thr Gly Ser Val Val Leu Asn Ser Ser Ser Glu Ser
                1175                1180                1185

 Asp Asp Ser Ser Leu Asp Met Ser Leu Lys Ala Phe Asp His Glu
                1190                1195                1200

 Asn Thr Ser Glu Leu Tyr Lys Glu Leu Leu Glu Asn Glu Lys Lys
                1205                1210                1215

 Asn Phe His Leu Val Arg Ser Ala Val Arg Asp Leu Gly Gly Ile
                1220                1225                1230

 Pro Ala Met Ile Asn His Ser Asp Met Ser Asn Thr Ile Pro Asp
                1235                1240                1245

 Glu Lys Val Val Ile Thr Tyr Leu Ser Phe Leu Cys Ala Arg Leu
                1250                1255                1260

 Leu Asp Leu Arg Lys Glu Ile Arg Ala Ala Arg Leu Ile Gln Thr
                1265                1270                1275

 Thr Trp Arg Lys Tyr Lys Leu Lys Thr Asp Leu Lys Arg His Gln
                1280                1285                1290

 Glu Arg Glu Lys Ala Ala Arg Ile Ile Gln Leu Ala Val Ile Asn
                1295                1300                1305

 Phe Leu Ala Lys Gln Arg Leu Arg Lys Arg Val Asn Ala Ala Leu
                1310                1315                1320

 Val Ile Gln Lys Tyr Trp Arg Arg Val Leu Ala Gln Arg Lys Leu
                1325                1330                1335

 Leu Met Leu Lys Lys Glu Lys Leu Glu Lys Val Gln Asn Lys Ala
                1340                1345                1350

 Ala Ser Leu Ile Gln Gly Tyr Trp Arg Arg Tyr Ser Thr Arg Gln
                1355                1360                1365

 Arg Phe Leu Lys Leu Lys Tyr Tyr Ser Ile Ile Leu Gln Ser Arg
                1370                1375                1380

 Ile Arg Met Ile Ile Ala Val Thr Ser Tyr Lys Arg Tyr Leu Trp
                1385                1390                1395

 Ala Thr Val Thr Ile Gln Arg His Trp Arg Ala Tyr Leu Arg Arg
                1400                1405                1410

 Lys Gln Asp Gln Gln Arg Tyr Glu Met Leu Lys Ser Ser Thr Leu
                1415                1420                1425

 Ile Ile Gln Ser Met Phe Arg Lys Trp Lys Gln Arg Lys Met Gln
                1430                1435                1440

 Ser Gln Val Lys Ala Thr Val Ile Leu Gln Arg Ala Phe Arg Glu
                1445                1450                1455

 Trp His Leu Arg Lys Gln Ala Lys Glu Glu Asn Ser Ala Ile Ile
                1460                1465                1470

 Ile Gln Ser Trp Tyr Arg Met His Lys Glu Leu Arg Lys Tyr Ile
                1475                1480                1485

 Tyr Ile Arg Ser Cys Val Val Ile Ile Gln Lys Arg Phe Arg Cys
                1490                1495                1500

 Phe Gln Ala Gln Lys Leu Tyr Lys Arg Arg Lys Glu Ser Ile Leu
                1505                1510                1515

 Thr Ile Gln Lys Tyr Tyr Lys Ala Tyr Leu Lys Gly Lys Ile Glu
                1520                1525                1530

 Arg Thr Asn Tyr Leu Gln Lys Arg Ala Ala Ala Ile Gln Leu Gln
                1535                1540                1545

 Ala Ala Phe Arg Arg Leu Lys Ala His Asn Leu Cys Arg Gln Ile
                1550                1555                1560

 Arg Ala Ala Cys Val Ile Gln Ser Tyr Trp Arg Met Arg Gln Asp
                1565                1570                1575

 Arg Val Arg Phe Leu Asn Leu Lys Lys Thr Ile Ile Lys Phe Gln
                1580                1585                1590

 Ala His Val Arg Lys His Gln Gln Arg Gln Lys Tyr Lys Lys Met
                1595                1600                1605

 Lys Lys Ala Ala Val Ile Ile Gln Thr His Phe Arg Ala Tyr Ile
                1610                1615                1620

 Phe Ala Met Lys Val Leu Ala Ser Tyr Gln Lys Thr Arg Ser Ala
                1625                1630                1635

 Val Ile Val Leu Gln Ser Ala Tyr Arg Gly Met Gln Ala Arg Lys
                1640                1645                1650

 Met Tyr Ile His Ile Leu Thr Ser Val Ile Lys Ile Gln Ser Tyr
                1655                1660                1665

 Tyr Arg Ala Tyr Val Ser Lys Lys Glu Phe Leu Ser Leu Lys Asn
                1670                1675                1680

 Ala Thr Ile Lys Leu Gln Ser Thr Val Lys Met Lys Gln Thr Arg
                1685                1690                1695

 Lys Gln Tyr Leu His Leu Arg Ala Ala Ala Leu Phe Ile Gln Gln
                1700                1705                1710

 Cys Tyr Arg Ser Lys Lys Ile Ala Ala Gln Lys Arg Glu Glu Tyr
                1715                1720                1725

 Met Gln Met Arg Glu Ser Cys Ile Lys Leu Gln Ala Phe Val Arg
                1730                1735                1740

 Gly Tyr Leu Val Arg Lys Gln Met Arg Leu Gln Arg Lys Ala Val
                1745                1750                1755

 Ile Ser Leu Gln Ser Tyr Phe Arg Met Arg Lys Ala Arg Gln Tyr
                1760                1765                1770

 Tyr Leu Lys Met Tyr Lys Ala Ile Ile Val Ile Gln Asn Tyr Tyr
                1775                1780                1785

 His Ala Tyr Lys Ala Gln Val Asn Gln Arg Lys Asn Phe Leu Gln
                1790                1795                1800

 Val Lys Lys Ala Ala Thr Cys Leu Gln Ala Ala Tyr Arg Gly Tyr
                1805                1810                1815

 Lys Val Arg Gln Leu Ile Lys Gln Gln Ser Ile Ala Ala Leu Lys
                1820                1825                1830

 Ile Gln Ser Ala Phe Arg Gly Tyr Asn Lys Arg Val Lys Tyr Gln
                1835                1840                1845

 Ser Val Leu Gln Ser Ile Ile Lys Ile Gln Arg Trp Tyr Arg Ala
                1850                1855                1860

 Tyr Lys Thr Leu His Asp Thr Arg Thr His Phe Leu Lys Thr Lys
                1865                1870                1875

 Ala Ala Val Ile Ser Leu Gln Ser Ala Tyr Arg Gly Trp Lys Val
                1880                1885                1890

 Arg Lys Gln Ile Arg Arg Glu His Gln Ala Ala Leu Lys Ile Gln
                1895                1900                1905

 Ser Ala Phe Arg Met Ala Lys Ala Gln Lys Gln Phe Arg Leu Phe
                1910                1915                1920

 Lys Thr Ala Ala Leu Val Ile Gln Gln Asn Phe Arg Ala Trp Thr
                1925                1930                1935

 Ala Gly Arg Lys Gln Cys Met Glu Tyr Ile Glu Leu Arg His Ala
                1940                1945                1950

 Val Leu Val Leu Gln Ser Met Trp Lys Gly Lys Thr Leu Arg Arg
                1955                1960                1965

 Gln Leu Gln Arg Gln His Lys Cys Ala Ile Ile Ile Gln Ser Tyr
                1970                1975                1980

 Tyr Arg Met His Val Gln Gln Lys Lys Trp Lys Ile Met Lys Lys
                1985                1990                1995

 Ala Ala Leu Leu Ile
                2000

<210> 3489
<211> 1152
<212> DNA
<213> Homo sapien

<400> 3489
 aaggctatta ttaccaccac tgagtggctt aaataatcct gtcaacagca 50

 atcgcccatt tccaaagcca tggtgaaaca tctctgtgct aatttctttt 100

 gttttgtttc ctaatttttt ttttttggca ggtggtggga aataatcttt 150

 gtcttctttg gagtaaacct tcaacaccgg attttttctt ttaattatgg 200

 atgtaaaccc caatatcccc ataatttaca ttgggtctcg accaattgcc 250

 taattataag aggatatatt taggctctta tttcatccac acaaaaactt 300

 gtgtaacagg tagttggaaa catctgaggc accactttga ttctgttttg 350

 gatggtcatg ttttttctcc tccgtttccc cagcatgtct gccaccatcc 400

 tcatgcactg cttccaagtg cctgggagcc tttatgagcg tccctaaacc 450

 taaaagaatc cagaggcggg gctcggatga accctcgaga taagcaagtg 500

 agccgcttct cccctctaaa ggatgtttac acgtgggtgg cactcgctgg 550

 aatccagcgc tcgggcagcc ctgggaggac gcgctcagct gcgaggagga 600

 tggagagcaa tacatcatca tctttggaga atttagcgac ggcgcctgtg 650

 aaccagatcc aagaaacaat ttctgataat tgtgtggtga ttttctcaaa 700

 aacatcctgt tcttactgta caatggcaaa aaagcttttc catgacatga 750

 atgttaacta taaagtggtg gaactggacc tgcttgaata tggaaaccag 800

 ttccaagatg ctctttacaa aatgactggt gaaagaactg ttccaagaat 850

 atttgtcaat ggtactttta ttggaggtgc aactgacact cataggcttc 900

 acaaagaagg aaaattgctc ccactagttc atcagtgtta tttaaaaaaa 950

 agtaagagga aagaatttca gtgatgttta tactaataag tttgctagta 1000

 cagtgtcagt tatttaaagt ggtaatgccc gataatgtct tttaaatgtt 1050

 tgaggatgtt ttaaatacat gcattgtctt cacgaagaag atgtaaaaat 1100

 aatgaacaat aaattgcggt ggaaacctaa aaaaaaaaaa aaaaaaaaaa 1150

 aa 1152

<210> 3490
<211> 165
<212> PRT
<213> Homo sapien

<400> 3490
 Met Asn Pro Arg Asp Lys Gln Val Ser Arg Phe Ser Pro Leu Lys
   1               5                  10                  15

 Asp Val Tyr Thr Trp Val Ala Leu Ala Gly Ile Gln Arg Ser Gly
                  20                  25                  30

 Ser Pro Gly Arg Thr Arg Ser Ala Ala Arg Arg Met Glu Ser Asn
                  35                  40                  45

 Thr Ser Ser Ser Leu Glu Asn Leu Ala Thr Ala Pro Val Asn Gln
                  50                  55                  60

 Ile Gln Glu Thr Ile Ser Asp Asn Cys Val Val Ile Phe Ser Lys
                  65                  70                  75

 Thr Ser Cys Ser Tyr Cys Thr Met Ala Lys Lys Leu Phe His Asp
                  80                  85                  90

 Met Asn Val Asn Tyr Lys Val Val Glu Leu Asp Leu Leu Glu Tyr
                  95                 100                 105

 Gly Asn Gln Phe Gln Asp Ala Leu Tyr Lys Met Thr Gly Glu Arg
                 110                 115                 120

 Thr Val Pro Arg Ile Phe Val Asn Gly Thr Phe Ile Gly Gly Ala
                 125                 130                 135

 Thr Asp Thr His Arg Leu His Lys Glu Gly Lys Leu Leu Pro Leu
                 140                 145                 150

 Val His Gln Cys Tyr Leu Lys Lys Ser Lys Arg Lys Glu Phe Gln
                 155                 160                 165

<210> 3491
<211> 1708
<212> DNA
<213> Homo sapien

<400> 3491
 aatcgcagcc atggcgtcgt tactgtgggg aggcgacgca ggggcggcgg 50

 agagcgagcg gctgaacagc cacttttcaa acctcagcca accccggaag 100

 aacctttggg gtattaagag tactgcagtc cgaaacatag atggttctat 150

 taataacatc aatgaagatg atgaagaaga tgtagtggat ttggcagcta 200

 attcactctt aaacaagtta atccatcaat ccttagtaga atccagtcac 250

 cgtgtggaag ttttacagaa ggatcccagc tctccacttt actcagtaaa 300

 gacatttgaa gagctgcggc taaaggaaga gttactaaaa ggaatctatg 350

 caatgggatt taataggcca tctaaaatcc aagagatggc tctccctatg 400

 atgctggcac atccacccca gaacctcata gcacagagcc agtctggaac 450

 aggaaagaca gcggcatttg tgttggcaat gttaagcaga gttaatgcct 500

 tggaattgtt cccacagtgc ctctgcctag ctcctactta tgaattggct 550

 ctgcaaactg gccgtgtggt tgagcagatg ggaaaattct gtgtggatgt 600

 tcaagtgatg tatgccattc gagggaatcg aattcccaga ggcaccgaca 650

 tcactaaaca gattataatt ggcactcctg ggactgtcct agattggtgt 700

 tttaaactaa aattgattga tttgactaag attcgtgtgt ttgtcctgga 750

 tgaagcagat gtgatgattg acactcaagg attctcagat catagtattc 800

 gtattcaaag agctctaccc tccgaatgcc aaatgctcct cttttcagca 850

 acctttgagg actctgtgtg gcactttgct gagcgaatca tccctgaccc 900

 taatgttatc aagttacgca aagaggagct cacactgaac aacatccggc 950

 aatattacgt gctgtgtgag cacaggaaag acaaatacca agctctgtgc 1000

 aacatttatg gcagcatcac cattggtcag gccatcatct tctgccagac 1050

 tcgtcgaaac gctaagtggt tgaccgtgga gatgatacag gatggccacc 1100

 aggtgtcttt gttaagcggg gagctgaccg tggagcagcg agcttccatc 1150

 attcagaggt ttcgggatgg gaaagagaag gttctcataa caactaatgt 1200

 ttgtgcccga gggattgatg tgaagcaggt cacaattgtt gtgaactttg 1250

 atctccctgt aaaacaagga gaggagccgg actatgagac ctacctccac 1300

 cgcatagggc ggacggggcg ctttgggaaa aaaggccttg ccttcaacat 1350

 gattgaagta gatgagctgc cctcgctcat gaaaatccag gaccacttta 1400

 acagcagtat taagcaactc aacgctgaag acatggatga aattgaaaag 1450

 attgactatt gaagaaagaa ctttattgtt tgtgcagtat cctagtttat 1500

 gtgagaatgt ctcagtgggt tttgaaggta atttttttat gttgaggctt 1550

 tttcgacgtg aaactgtcac agatggcaaa ataaatgtca cggtacttag 1600

 ttttaagaca tgaggtcttt ttgaagccaa attgatgtga agcttgtgat 1650

 ccttttgaat aaaaaaaagg caagattatt tcttattcta aaaaaaaaaa 1700

 aaaaaaaa 1708

<210> 3492
<211> 369
<212> PRT
<213> Homo sapien

<400> 3492
 Met Gly Phe Asn Arg Pro Ser Lys Ile Gln Glu Met Ala Leu Pro
   1               5                  10                  15

 Met Met Leu Ala His Pro Pro Gln Asn Leu Ile Ala Gln Ser Gln
                  20                  25                  30

 Ser Gly Thr Gly Lys Thr Ala Ala Phe Val Leu Ala Met Leu Ser
                  35                  40                  45

 Arg Val Asn Ala Leu Glu Leu Phe Pro Gln Cys Leu Cys Leu Ala
                  50                  55                  60

 Pro Thr Tyr Glu Leu Ala Leu Gln Thr Gly Arg Val Val Glu Gln
                  65                  70                  75

 Met Gly Lys Phe Cys Val Asp Val Gln Val Met Tyr Ala Ile Arg
                  80                  85                  90

 Gly Asn Arg Ile Pro Arg Gly Thr Asp Ile Thr Lys Gln Ile Ile
                  95                 100                 105

 Ile Gly Thr Pro Gly Thr Val Leu Asp Trp Cys Phe Lys Leu Lys
                 110                 115                 120

 Leu Ile Asp Leu Thr Lys Ile Arg Val Phe Val Leu Asp Glu Ala
                 125                 130                 135

 Asp Val Met Ile Asp Thr Gln Gly Phe Ser Asp His Ser Ile Arg
                 140                 145                 150

 Ile Gln Arg Ala Leu Pro Ser Glu Cys Gln Met Leu Leu Phe Ser
                 155                 160                 165

 Ala Thr Phe Glu Asp Ser Val Trp His Phe Ala Glu Arg Ile Ile
                 170                 175                 180

 Pro Asp Pro Asn Val Ile Lys Leu Arg Lys Glu Glu Leu Thr Leu
                 185                 190                 195

 Asn Asn Ile Arg Gln Tyr Tyr Val Leu Cys Glu His Arg Lys Asp
                 200                 205                 210

 Lys Tyr Gln Ala Leu Cys Asn Ile Tyr Gly Ser Ile Thr Ile Gly
                 215                 220                 225

 Gln Ala Ile Ile Phe Cys Gln Thr Arg Arg Asn Ala Lys Trp Leu
                 230                 235                 240

 Thr Val Glu Met Ile Gln Asp Gly His Gln Val Ser Leu Leu Ser
                 245                 250                 255

 Gly Glu Leu Thr Val Glu Gln Arg Ala Ser Ile Ile Gln Arg Phe
                 260                 265                 270

 Arg Asp Gly Lys Glu Lys Val Leu Ile Thr Thr Asn Val Cys Ala
                 275                 280                 285

 Arg Gly Ile Asp Val Lys Gln Val Thr Ile Val Val Asn Phe Asp
                 290                 295                 300

 Leu Pro Val Lys Gln Gly Glu Glu Pro Asp Tyr Glu Thr Tyr Leu
                 305                 310                 315

 His Arg Ile Gly Arg Thr Gly Arg Phe Gly Lys Lys Gly Leu Ala
                 320                 325                 330

 Phe Asn Met Ile Glu Val Asp Glu Leu Pro Ser Leu Met Lys Ile
                 335                 340                 345

 Gln Asp His Phe Asn Ser Ser Ile Lys Gln Leu Asn Ala Glu Asp
                 350                 355                 360

 Met Asp Glu Ile Glu Lys Ile Asp Tyr
                 365

<210> 3493
<211> 1599
<212> DNA
<213> Homo sapien

<400> 3493
 agatgcggtg gtggccgccg agcgcctgga aggagctgct ggacaggccg 50

 agggagcctc cgcccgagac cgcgcagccg ccgccgccat ggctacaaaa 100

 gaccccacag ctgtagagag agcaaacttg ttaaacatgg ctaaactgag 150

 tatcaaagga ctcattgaat ctgctctgag ctttggccgc actttggatt 200

 ctgactatcc ccccttgcag caattctttg ttgttatgga acattgcctg 250

 aaacacggtc ttaaagtaag aaaatcattt ttgagttaca acaaaaccat 300

 ctggggccct ttggaactgg tggagaagct gtaccccgaa gcagaggaaa 350

 taggagctag tgtccgggat ctacctggtc tgaagacccc tctgggtcga 400

 gcaagagcgt ggcttcgatt agccctcatg cagaaaaaaa tggccgatta 450

 cttacgttgc ttaattattc agagggatct cttgagtgag ttttatgagt 500

 atcacgcact aatgatggaa gaagaaggag cagtaattgt tgggctgctg 550

 gttggcctga atgtgatcga tgctaatctg tgtgtgaagg gagaggattt 600

 agactcacga gttggagtga ttgatttttc tatgtattta aagaatgaag 650

 aagatattgg aaataaagaa aggtatgatt ttcataagtt atttcacata 700

 ttgggttttt tatatagctc tttacaaatc attataagat ccatctattt 750

 acagtgtggt tttattttgt tgttttcccc cctgtgactt cttcatttca 800

 ttttcacttc cattacaagc tttacaaagc agattatgga aaatcactta 850

 ggagaaggag gttttattaa tagtatgaag tgggaccttt ggttatacct 900

 gtagttactg agacccattt taatagtggt tttttggaat aaaagagatg 950

 aaagcttatt attcacaagt ttgcaaatac tggggaggct gaggcaggag 1000

 aatcgcttga acccgggaag cagaggttgc agtgagccga gatcgcacca 1050

 ctgcactcca acctgggtga cagagcaaga ctccatctca aaaacaaaga 1100

 aacactgaac agttatccta tctgatcttt ttatatgcag gatagtgatt 1150

 aaatcactct acaaccactt tcctctaatt tctcctcata agcctaatca 1200

 aatgtatttg ccttacttcc taccattctg ttgaagattc tccgaaaatt 1250

 ggagaaagca ctaaatatgg taggaagatt ctcttgaagt tcctgtgatc 1300

 ttttgaaact gcattcctga gttctatcct tacttcctta aagcagcatg 1350

 cacttttggt ttgttgttaa tcaggggtct cctgtgcttg gtgtgtgggg 1400

 taggaaggca ggtgatcacc tgcaacaatt cttcacagat tggaagttaa 1450

 acatgaaaag cccccggaga ccccacgaac tagatgccag aaagttctgc 1500

 agtcattgac tgttaactgc aattccaact atacggtcag ccctccatat 1550

 ccatgggttc catatccgtg gattcaacca acatggattg aaatattcc 1599

<210> 3494
<211> 232
<212> PRT
<213> Homo sapien

<400> 3494
 Met Ala Thr Lys Asp Pro Thr Ala Val Glu Arg Ala Asn Leu Leu
   1               5                  10                  15

 Asn Met Ala Lys Leu Ser Ile Lys Gly Leu Ile Glu Ser Ala Leu
                  20                  25                  30

 Ser Phe Gly Arg Thr Leu Asp Ser Asp Tyr Pro Pro Leu Gln Gln
                  35                  40                  45

 Phe Phe Val Val Met Glu His Cys Leu Lys His Gly Leu Lys Val
                  50                  55                  60

 Arg Lys Ser Phe Leu Ser Tyr Asn Lys Thr Ile Trp Gly Pro Leu
                  65                  70                  75

 Glu Leu Val Glu Lys Leu Tyr Pro Glu Ala Glu Glu Ile Gly Ala
                  80                  85                  90

 Ser Val Arg Asp Leu Pro Gly Leu Lys Thr Pro Leu Gly Arg Ala
                  95                 100                 105

 Arg Ala Trp Leu Arg Leu Ala Leu Met Gln Lys Lys Met Ala Asp
                 110                 115                 120

 Tyr Leu Arg Cys Leu Ile Ile Gln Arg Asp Leu Leu Ser Glu Phe
                 125                 130                 135

 Tyr Glu Tyr His Ala Leu Met Met Glu Glu Glu Gly Ala Val Ile
                 140                 145                 150

 Val Gly Leu Leu Val Gly Leu Asn Val Ile Asp Ala Asn Leu Cys
                 155                 160                 165

 Val Lys Gly Glu Asp Leu Asp Ser Arg Val Gly Val Ile Asp Phe
                 170                 175                 180

 Ser Met Tyr Leu Lys Asn Glu Glu Asp Ile Gly Asn Lys Glu Arg
                 185                 190                 195

 Tyr Asp Phe His Lys Leu Phe His Ile Leu Gly Phe Leu Tyr Ser
                 200                 205                 210

 Ser Leu Gln Ile Ile Ile Arg Ser Ile Tyr Leu Gln Cys Gly Phe
                 215                 220                 225

 Ile Leu Leu Phe Ser Pro Leu
                 230

<210> 3495
<211> 2887
<212> DNA
<213> Homo sapien

<400> 3495
 gaagcagcag gtaccccctc cacatcccta gggctctgtg atgtaggcag 50

 aggcccgtgg gagtcagcat gccgcgtggc tgggccgccc ccttgctcct 100

 gctgctgctc cagggaggct ggggctgccc cgacctcgtc tgctacaccg 150

 attacctcca gacggtcatc tgcatcctgg aaatgtggaa cctccacccc 200

 agcacgctca cccttacctg gcaagaccag tatgaagagc tgaaggacga 250

 ggccacctcc tgcagcctcc acaggtcggc ccacaatgcc acgcatgcca 300

 cctacacctg ccacatggat gtattccact tcatggccga cgacattttc 350

 agtgtcaaca tcacagacca gtctggcaac tactcccagg agtgtggcag 400

 ctttctcctg gctgagagca tcaagccggc tccccctttc aacgtgactg 450

 tgaccttctc aggacagtat aatatctcct ggcgctcaga ttacgaagac 500

 cctgccttct acatgctgaa gggcaagctt cagtatgagc tgcagtacag 550

 gaaccgggga gacccctggg ctgtgagtcc gaggagaaag ctgatctcag 600

 tggactcaag aagtgtctcc ctcctccccc tggagttccg caaagactcg 650

 agctatgagc tgcaggtgcg ggcagggccc atgcctggct cctcctacca 700

 ggggacctgg agtgaatgga gtgacccggt catctttcag acccagtcag 750

 aggagttaaa ggaaggctgg aaccctcacc tgctgcttct cctcctgctt 800

 gtcatagtct tcattcctgc cttctggagc ctgaagaccc atccattgtg 850

 gaggctatgg aagaagatat gggccgtccc cagccctgag cggttcttca 900

 tgcccctgta caagggctgc agcggagact tcaagaaatg ggtgggtgca 950

 cccttcactg gctccagcct ggagctggga ccctggagcc cagaggtgcc 1000

 ctccaccctg gaggtgtaca gctgccaccc accacggagc ccggccaaga 1050

 ggctgcagct cacggagcta caagaaccag cagagctggt ggagtctgac 1100

 ggtgtgccca agcccagctt ctggccgaca gcccagaact cggggggctc 1150

 agcttacagt gaggagaggg atcggccata cggcctggtg tccattgaca 1200

 cagtgactgt gctagatgca gaggggccat gcacctggcc ctgcagctgt 1250

 gaggatgacg gctacccagc cctggacctg gatgctggcc tggagcccag 1300

 cccaggccta gaggacccac tcttggatgc agggaccaca gtcctgtcct 1350

 gtggctgtgt ctcagctggc agccctgggc taggagggcc cctgggaagc 1400

 ctcctggaca gactaaagcc accccttgca gatggggagg actgggctgg 1450

 gggactgccc tggggtggcc ggtcacctgg aggggtctca gagagtgagg 1500

 cgggctcacc cctggccggc ctggatatgg acacgtttga cagtggcttt 1550

 gtgggctctg actgcagcag ccctgtggag tgtgacttca ccagccccgg 1600

 ggacgaagga cccccccgga gctacctccg ccagtgggtg gtcattcctc 1650

 cgccactttc gagccctgga ccccaggcca gctaatgagg ctgactggat 1700

 gtccagagct ggccaggcca ctgggccctg agccagagac aaggtcacct 1750

 gggctgtgat gtgaagacac ctgcagcctt tggtctcctg gatgggcctt 1800

 tgagcctgat gtttacagtg tctgtgtgtg tgtgtgcata tgtgtgtgtg 1850

 tgcatatgca tgtgtgtgtg tgtgtgtgtc ttaggtgcgc agtggcatgt 1900

 ccacgtgtgt gtgtgattgc acgtgcctgt gggcctggga taatgcccat 1950

 ggtactccat gcattcacct gccctgtgca tgtctggact cacggagctc 2000

 acccatgtgc acaagtgtgc acagtaaacg tgtttgtggt caacagatga 2050

 caacagccgt cctccctcct agggtcttgt gttgcaagtt ggtccacagc 2100

 atctccgggg ctttgtggga tcagggcatt gcctgtgact gaggcggagc 2150

 ccagccctcc agcgtctgcc tccaggagct gcaagaagtc catattgttc 2200

 cttatcacct gccaacagga agcgaaaggg gatggagtga gcccatggtg 2250

 acctcgggaa tggcaatttt ttgggcggcc cctggacgaa ggtctgaatc 2300

 ccgactctga taccttctgg ctgtgctacc tgagccaagt cgcctcccct 2350

 ctctgggcta gagtttcctt atccagacag tggggaaggc atgacacacc 2400

 tgggggaaat tggcgatgtc acccgtgtac ggtacgcagc ccagagcaga 2450

 ccctcaataa acgtcagctt ccttccttct gcggccagag ccgaggcggg 2500

 cgggggtgag aacatcaatc gtcagcgaca gcctgggcac ccgcggggcc 2550

 gtcccgcctg cagagggcca ctcggggggg tttccaggct taaaatcagt 2600

 ccgtttcgtc tcttggaaac agctccccac caaccaagat ttctttttct 2650

 aacttctgct actaagtttt taaaaattcc ctttatgcac ccaagagata 2700

 tttattaaac accaattacg tagcaggcca tggctcatgg gacccacccc 2750

 ccgtggcact catggagggg gctgcaggtt ggaactatgc agtgtgctcc 2800

 ggccacacat cctgctgggc cccctaccct gccccaattc aatcctgcca 2850

 ataaatcctg tcttatttgt tcatcctgga gaattga 2887

<210> 3496
<211> 538
<212> PRT
<213> Homo sapien

<400> 3496
 Met Pro Arg Gly Trp Ala Ala Pro Leu Leu Leu Leu Leu Leu Gln
   1               5                  10                  15

 Gly Gly Trp Gly Cys Pro Asp Leu Val Cys Tyr Thr Asp Tyr Leu
                  20                  25                  30

 Gln Thr Val Ile Cys Ile Leu Glu Met Trp Asn Leu His Pro Ser
                  35                  40                  45

 Thr Leu Thr Leu Thr Trp Gln Asp Gln Tyr Glu Glu Leu Lys Asp
                  50                  55                  60

 Glu Ala Thr Ser Cys Ser Leu His Arg Ser Ala His Asn Ala Thr
                  65                  70                  75

 His Ala Thr Tyr Thr Cys His Met Asp Val Phe His Phe Met Ala
                  80                  85                  90

 Asp Asp Ile Phe Ser Val Asn Ile Thr Asp Gln Ser Gly Asn Tyr
                  95                 100                 105

 Ser Gln Glu Cys Gly Ser Phe Leu Leu Ala Glu Ser Ile Lys Pro
                 110                 115                 120

 Ala Pro Pro Phe Asn Val Thr Val Thr Phe Ser Gly Gln Tyr Asn
                 125                 130                 135

 Ile Ser Trp Arg Ser Asp Tyr Glu Asp Pro Ala Phe Tyr Met Leu
                 140                 145                 150

 Lys Gly Lys Leu Gln Tyr Glu Leu Gln Tyr Arg Asn Arg Gly Asp
                 155                 160                 165

 Pro Trp Ala Val Ser Pro Arg Arg Lys Leu Ile Ser Val Asp Ser
                 170                 175                 180

 Arg Ser Val Ser Leu Leu Pro Leu Glu Phe Arg Lys Asp Ser Ser
                 185                 190                 195

 Tyr Glu Leu Gln Val Arg Ala Gly Pro Met Pro Gly Ser Ser Tyr
                 200                 205                 210

 Gln Gly Thr Trp Ser Glu Trp Ser Asp Pro Val Ile Phe Gln Thr
                 215                 220                 225

 Gln Ser Glu Glu Leu Lys Glu Gly Trp Asn Pro His Leu Leu Leu
                 230                 235                 240

 Leu Leu Leu Leu Val Ile Val Phe Ile Pro Ala Phe Trp Ser Leu
                 245                 250                 255

 Lys Thr His Pro Leu Trp Arg Leu Trp Lys Lys Ile Trp Ala Val
                 260                 265                 270

 Pro Ser Pro Glu Arg Phe Phe Met Pro Leu Tyr Lys Gly Cys Ser
                 275                 280                 285

 Gly Asp Phe Lys Lys Trp Val Gly Ala Pro Phe Thr Gly Ser Ser
                 290                 295                 300

 Leu Glu Leu Gly Pro Trp Ser Pro Glu Val Pro Ser Thr Leu Glu
                 305                 310                 315

 Val Tyr Ser Cys His Pro Pro Arg Ser Pro Ala Lys Arg Leu Gln
                 320                 325                 330

 Leu Thr Glu Leu Gln Glu Pro Ala Glu Leu Val Glu Ser Asp Gly
                 335                 340                 345

 Val Pro Lys Pro Ser Phe Trp Pro Thr Ala Gln Asn Ser Gly Gly
                 350                 355                 360

 Ser Ala Tyr Ser Glu Glu Arg Asp Arg Pro Tyr Gly Leu Val Ser
                 365                 370                 375

 Ile Asp Thr Val Thr Val Leu Asp Ala Glu Gly Pro Cys Thr Trp
                 380                 385                 390

 Pro Cys Ser Cys Glu Asp Asp Gly Tyr Pro Ala Leu Asp Leu Asp
                 395                 400                 405

 Ala Gly Leu Glu Pro Ser Pro Gly Leu Glu Asp Pro Leu Leu Asp
                 410                 415                 420

 Ala Gly Thr Thr Val Leu Ser Cys Gly Cys Val Ser Ala Gly Ser
                 425                 430                 435

 Pro Gly Leu Gly Gly Pro Leu Gly Ser Leu Leu Asp Arg Leu Lys
                 440                 445                 450

 Pro Pro Leu Ala Asp Gly Glu Asp Trp Ala Gly Gly Leu Pro Trp
                 455                 460                 465

 Gly Gly Arg Ser Pro Gly Gly Val Ser Glu Ser Glu Ala Gly Ser
                 470                 475                 480

 Pro Leu Ala Gly Leu Asp Met Asp Thr Phe Asp Ser Gly Phe Val
                 485                 490                 495

 Gly Ser Asp Cys Ser Ser Pro Val Glu Cys Asp Phe Thr Ser Pro
                 500                 505                 510

 Gly Asp Glu Gly Pro Pro Arg Ser Tyr Leu Arg Gln Trp Val Val
                 515                 520                 525

 Ile Pro Pro Pro Leu Ser Ser Pro Gly Pro Gln Ala Ser
                 530                 535

<210> 3497
<211> 1323
<212> DNA
<213> Homo sapien

<400> 3497
 atgatcatcc cctctctaga ggagctggac tccctcaagt acagtgacct 50

 gcagaactta gccaagagtc tgggtctccg ggccaacctg agggcaacca 100

 agttgttaaa agccttgaaa ggctacatta aacatgaggc aagaaaagga 150

 aatgagaatc aggatgaaag tcaaacttct gcatcctctt gtgatgagac 200

 tgagatacag atcagcaacc aggaagaagc tgagagacag ccacttggcc 250

 atgtcaccaa aacaaggaga aggtgcaaga ctgtccgtgt ggaccctgac 300

 tcacagcaga atcattcaga gataaaaata agtaatccca ctgaattcca 350

 gaatcatgaa aagcaggaaa gccaggatct cagagctact gcaaaagttc 400

 cttctccacc agacgagcac caagaagctg agaatgctgt ttcctcaggt 450

 aacagagatt caaaggtacc ttcagaagga aagaaatctc tctacacaga 500

 tgagtcatcc aaacctggaa aaaataaaag aactgcaatc actactccaa 550

 actttaagaa gcttcatgaa gctcatttta aggaaatgga gtccattgat 600

 caatatattg agagaaaaaa gaaacatttt gaagaacaca attccatgaa 650

 tgaactgaag cagcccatca ataagggagg ggtcaggact ccagtacctc 700

 caagaggaag actctctgtg gcttctactc ccatcagcca acgacgctcg 750

 caaggccggt cttgtggccc tgcaagtcag agtaccttgg gtctgaaggg 800

 gtcactcaag cgctctgcta tctctgcagc taaaacgggt gtcaggtttt 850

 cagctgctac taaagataat gagcataagc gttcactgac caagactcca 900

 gccagaaagt ctgcacatgt gaccgtgtct gggggcaccc caaaaggcga 950

 ggctgtgctt gggacacaca aattaaagac catcacgggg aattctgctg 1000

 ctgttattac cccattcaag ttgacaactg aggcaacgca gactccagtc 1050

 tccaataaga aaccagtgtt tgatcttaaa gcaagtttgt ctcgtcccct 1100

 caactatgaa ccacacaaag gaaagctaaa accatggggg caatctaaag 1150

 aaaataatta tctaaatcaa catgtcaaca gaattaactt ctacaagaaa 1200

 acttacaaac aaccccatct ccagacaaag gaagagcaac ggaagaaacg 1250

 cgagcaagaa cgaaaggaga agaaagcaaa ggttttggga atgcgaaggg 1300

 gcctcatttt ggctgaagat taa 1323

<210> 3498
<211> 440
<212> PRT
<213> Homo sapien

<400> 3498
 Met Ile Ile Pro Ser Leu Glu Glu Leu Asp Ser Leu Lys Tyr Ser
   1               5                  10                  15

 Asp Leu Gln Asn Leu Ala Lys Ser Leu Gly Leu Arg Ala Asn Leu
                  20                  25                  30

 Arg Ala Thr Lys Leu Leu Lys Ala Leu Lys Gly Tyr Ile Lys His
                  35                  40                  45

 Glu Ala Arg Lys Gly Asn Glu Asn Gln Asp Glu Ser Gln Thr Ser
                  50                  55                  60

 Ala Ser Ser Cys Asp Glu Thr Glu Ile Gln Ile Ser Asn Gln Glu
                  65                  70                  75

 Glu Ala Glu Arg Gln Pro Leu Gly His Val Thr Lys Thr Arg Arg
                  80                  85                  90

 Arg Cys Lys Thr Val Arg Val Asp Pro Asp Ser Gln Gln Asn His
                  95                 100                 105

 Ser Glu Ile Lys Ile Ser Asn Pro Thr Glu Phe Gln Asn His Glu
                 110                 115                 120

 Lys Gln Glu Ser Gln Asp Leu Arg Ala Thr Ala Lys Val Pro Ser
                 125                 130                 135

 Pro Pro Asp Glu His Gln Glu Ala Glu Asn Ala Val Ser Ser Gly
                 140                 145                 150

 Asn Arg Asp Ser Lys Val Pro Ser Glu Gly Lys Lys Ser Leu Tyr
                 155                 160                 165

 Thr Asp Glu Ser Ser Lys Pro Gly Lys Asn Lys Arg Thr Ala Ile
                 170                 175                 180

 Thr Thr Pro Asn Phe Lys Lys Leu His Glu Ala His Phe Lys Glu
                 185                 190                 195

 Met Glu Ser Ile Asp Gln Tyr Ile Glu Arg Lys Lys Lys His Phe
                 200                 205                 210

 Glu Glu His Asn Ser Met Asn Glu Leu Lys Gln Pro Ile Asn Lys
                 215                 220                 225

 Gly Gly Val Arg Thr Pro Val Pro Pro Arg Gly Arg Leu Ser Val
                 230                 235                 240

 Ala Ser Thr Pro Ile Ser Gln Arg Arg Ser Gln Gly Arg Ser Cys
                 245                 250                 255

 Gly Pro Ala Ser Gln Ser Thr Leu Gly Leu Lys Gly Ser Leu Lys
                 260                 265                 270

 Arg Ser Ala Ile Ser Ala Ala Lys Thr Gly Val Arg Phe Ser Ala
                 275                 280                 285

 Ala Thr Lys Asp Asn Glu His Lys Arg Ser Leu Thr Lys Thr Pro
                 290                 295                 300

 Ala Arg Lys Ser Ala His Val Thr Val Ser Gly Gly Thr Pro Lys
                 305                 310                 315

 Gly Glu Ala Val Leu Gly Thr His Lys Leu Lys Thr Ile Thr Gly
                 320                 325                 330

 Asn Ser Ala Ala Val Ile Thr Pro Phe Lys Leu Thr Thr Glu Ala
                 335                 340                 345

 Thr Gln Thr Pro Val Ser Asn Lys Lys Pro Val Phe Asp Leu Lys
                 350                 355                 360

 Ala Ser Leu Ser Arg Pro Leu Asn Tyr Glu Pro His Lys Gly Lys
                 365                 370                 375

 Leu Lys Pro Trp Gly Gln Ser Lys Glu Asn Asn Tyr Leu Asn Gln
                 380                 385                 390

 His Val Asn Arg Ile Asn Phe Tyr Lys Lys Thr Tyr Lys Gln Pro
                 395                 400                 405

 His Leu Gln Thr Lys Glu Glu Gln Arg Lys Lys Arg Glu Gln Glu
                 410                 415                 420

 Arg Lys Glu Lys Lys Ala Lys Val Leu Gly Met Arg Arg Gly Leu
                 425                 430                 435

 Ile Leu Ala Glu Asp
                 440

<210> 3499
<211> 2316
<212> DNA
<213> Homo sapien

<400> 3499
 ggataaaagc aagtttaaaa caaaaattag gaggttgtat gatatagcta 50

 atgttctgag tagcctggat cttatcaaga aagttcatgt tacagaggaa 100

 agaggccgaa aaccagcttt caaatggacc ggcccagaaa tcagtccaaa 150

 taccagtggc tccagcccag tcattcattt tactccctct gatttggagg 200

 tgagacggtc ttcaaaagag aactgtgcca aaaacctctt ttccacacgt 250

 gggaaaccaa actttactcg acacccatct cttatcaaat tggtaaagag 300

 tatagaaagt gatcggagaa agataaattc tgcgcccagt agccctatca 350

 agaccaacaa agctgagagt tctcagaatt ctgcaccctt cccaagtaaa 400

 atggctcagc tcgcagctat ttgtaaaatg cagttagaag agcaatcaag 450

 tgaatccaga cagaaagtga gagtacagct ggcaagatct ggaccctgca 500

 aaccagtagc ccctctggac cccccagtga atgctgagat ggagctgaca 550

 gcaccgtccc tcatccagcc cctgggaatg gttcccctga tccccagccc 600

 cttgtcatca gcagtgcccc tgatcctacc tcaggcccct tcaggcccat 650

 cctatgccat ctacctgcag cccactcaag cccaccaaag tgtgacgcca 700

 ccccaaggcc tgagcccaac ggtgtgcacc acccactctt ctaaagctac 750

 tggctcaaaa gactccacag atgccaccac tgagaaggca gccaatgata 800

 cctcaaaggc cagtgcctct accaggcctg gaagcttgct gccagcacca 850

 gagaggcaag gggcaaagag ccgaaccagg gagccagctg gagaaagagg 900

 ctcaaagagg gcaagcatgc tcgaggacag tggttccaaa aagaaattta 950

 aagaggacct aaaaggactt gaaaatgtct ccgcaacctt gttcccatca 1000

 ggatacctaa tccctctcac gcagtgctca tccctggggg cagagtccat 1050

 tttgtctggt aaagaaaact caagtgctct ttccccaaac cacaggattt 1100

 acagctcccc aattgcaggt gttattccag tgacatcatc tgaactcact 1150

 gctgttaatt ttccctcttt tcatgtaaca ccgttgaagc taatggtctc 1200

 accaacttcc gtggcagccg tacctgtcgg gaacagcccg gctctcgctt 1250

 caagccaccc tgttcccatc cagaacccaa gctcagccat tgtaaacttc 1300

 accctgcagc acctgggact catctcaccc aatgtgcagt tgtctgccag 1350

 ccctgggtct ggaatcgttc ctgtgtctcc aagaatagag tctgttaatg 1400

 tcgcaccaga aaatgcaggc actcagcaag gaagggccac caactatgac 1450

 tcaccagtcc caggccagag ccagccaaat ggacaatcag ttgctgtgac 1500

 aggggcacaa cagcctgttc ctgtgacacc caaagggtca caattagtgg 1550

 ccgaaagttt cttccgtacc ccaggtggac ccaccaagcc aaccagctca 1600

 tcctgcatgg attttgaggg tgctaataaa acctccttag gaactctctt 1650

 tgtcccacag cgaaaactgg aagtctcaac agaggatgtc cattaatcaa 1700

 cagatgttgg cttagtttaa ttttctaaag agttgtttaa tagagaaaat 1750

 gtacacagac tgatttggag aacacattct ctgaaaatac tgtaaatacg 1800

 ttggggattt gttcaatgtg aaatcagata gttgttttca tacatatata 1850

 tatatacaca cacacacaca cacacacaca cacacatata tttgtataaa 1900

 gctaagttta gctttcaatc ctacaaaata aaagtaaaat gttgaactct 1950

 aagatatatt aacttctagg gggaaaaatc cattatttta gctatgccta 2000

 tactattatg caaagtaact gtattaaagt ttacttccct ctaagcaaat 2050

 atgcttgaca tgcctaacac agcattccct taaacatttt gcacaaagaa 2100

 aatgctgtgt gatgtataat gttgtatttt taaatagggg tatagctata 2150

 ttttttgtaa tttctttaat ctgttgttgc agtgtatctt tttgtaaagt 2200

 ttgcaacaat cctcaatcaa gtctatggaa aaattattta taaaatgtat 2250

 ttttaatcat aagttgttca aattaaaact tttctaaaaa ataaaaaaaa 2300

 aaaaaaaaaa aaaaaa 2316

<210> 3500
<211> 431
<212> PRT
<213> Homo sapien

<400> 3500
 Met Ala Gln Leu Ala Ala Ile Cys Lys Met Gln Leu Glu Glu Gln
   1               5                  10                  15

 Ser Ser Glu Ser Arg Gln Lys Val Arg Val Gln Leu Ala Arg Ser
                  20                  25                  30

 Gly Pro Cys Lys Pro Val Ala Pro Leu Asp Pro Pro Val Asn Ala
                  35                  40                  45

 Glu Met Glu Leu Thr Ala Pro Ser Leu Ile Gln Pro Leu Gly Met
                  50                  55                  60

 Val Pro Leu Ile Pro Ser Pro Leu Ser Ser Ala Val Pro Leu Ile
                  65                  70                  75

 Leu Pro Gln Ala Pro Ser Gly Pro Ser Tyr Ala Ile Tyr Leu Gln
                  80                  85                  90

 Pro Thr Gln Ala His Gln Ser Val Thr Pro Pro Gln Gly Leu Ser
                  95                 100                 105

 Pro Thr Val Cys Thr Thr His Ser Ser Lys Ala Thr Gly Ser Lys
                 110                 115                 120

 Asp Ser Thr Asp Ala Thr Thr Glu Lys Ala Ala Asn Asp Thr Ser
                 125                 130                 135

 Lys Ala Ser Ala Ser Thr Arg Pro Gly Ser Leu Leu Pro Ala Pro
                 140                 145                 150

 Glu Arg Gln Gly Ala Lys Ser Arg Thr Arg Glu Pro Ala Gly Glu
                 155                 160                 165

 Arg Gly Ser Lys Arg Ala Ser Met Leu Glu Asp Ser Gly Ser Lys
                 170                 175                 180

 Lys Lys Phe Lys Glu Asp Leu Lys Gly Leu Glu Asn Val Ser Ala
                 185                 190                 195

 Thr Leu Phe Pro Ser Gly Tyr Leu Ile Pro Leu Thr Gln Cys Ser
                 200                 205                 210

 Ser Leu Gly Ala Glu Ser Ile Leu Ser Gly Lys Glu Asn Ser Ser
                 215                 220                 225

 Ala Leu Ser Pro Asn His Arg Ile Tyr Ser Ser Pro Ile Ala Gly
                 230                 235                 240

 Val Ile Pro Val Thr Ser Ser Glu Leu Thr Ala Val Asn Phe Pro
                 245                 250                 255

 Ser Phe His Val Thr Pro Leu Lys Leu Met Val Ser Pro Thr Ser
                 260                 265                 270

 Val Ala Ala Val Pro Val Gly Asn Ser Pro Ala Leu Ala Ser Ser
                 275                 280                 285

 His Pro Val Pro Ile Gln Asn Pro Ser Ser Ala Ile Val Asn Phe
                 290                 295                 300

 Thr Leu Gln His Leu Gly Leu Ile Ser Pro Asn Val Gln Leu Ser
                 305                 310                 315

 Ala Ser Pro Gly Ser Gly Ile Val Pro Val Ser Pro Arg Ile Glu
                 320                 325                 330

 Ser Val Asn Val Ala Pro Glu Asn Ala Gly Thr Gln Gln Gly Arg
                 335                 340                 345

 Ala Thr Asn Tyr Asp Ser Pro Val Pro Gly Gln Ser Gln Pro Asn
                 350                 355                 360

 Gly Gln Ser Val Ala Val Thr Gly Ala Gln Gln Pro Val Pro Val
                 365                 370                 375

 Thr Pro Lys Gly Ser Gln Leu Val Ala Glu Ser Phe Phe Arg Thr
                 380                 385                 390

 Pro Gly Gly Pro Thr Lys Pro Thr Ser Ser Ser Cys Met Asp Phe
                 395                 400                 405

 Glu Gly Ala Asn Lys Thr Ser Leu Gly Thr Leu Phe Val Pro Gln
                 410                 415                 420

 Arg Lys Leu Glu Val Ser Thr Glu Asp Val His
                 425                 430

<210> 3501
<211> 1586
<212> DNA
<213> Homo sapien

<400> 3501
 agtccctctt gcgtcgaggc tgcaaaatgg ttccattcgc caggagacgc 50

 tcctgagaga agggcgcgcg cggcacagag gccttccttg cacctcggag 100

 caaagcagct cggatagcgc cacacgtctg cgcgctgcgt gggaagggca 150

 gggctgacag cacttcctcc ccggggcagc gacctggagc ccgggtgcgg 200

 cagtctgcac cgcgcgtcgc tttcccggcc ggagtctcgc cgccttcccg 250

 cgccccgcag cgccccgcag agcagtcgag atgggtgagt caagtgaaga 300

 catagaccaa atgttcagca ctttgctggg agagatggat cttctgactc 350

 agagtttagg agttgacact ctccctcctc ctgaccctaa tccacccaga 400

 gctgaattta actacagtgt ggggtttaaa gatttaaatg agtccttaaa 450

 tgcactggaa gaccaagatt tagatgctct catggcagat ctggtagcag 500

 acataagtga ggctgagcag aggacaatcc aggcacagaa agagtccttg 550

 cagaatcaac atcattcagc atctctacaa gcatcaattt tcagtggtgc 600

 agcctctctt ggttatggaa caaatgttgc tgccactggt atcagccaat 650

 atgaggatga cttaccacct ccaccagccg atcctgtgtt agaccttcca 700

 ctgccaccac cacctcctga acctctctct caggaagagg aagaagccca 750

 agccaaggct gataaaatta agctggcgct ggaaaaactg aaggaggcca 800

 aggttaagaa gctcgtcgtc aaggtgcaca tgaatgataa cagcacaaag 850

 tcactgatgg tggatgagcg gcagctggcc cgagatgttc tggacaacct 900

 tttcgagaaa actcattgtg actgcaatgt agactggtgt ctttatgaaa 950

 tctacccgga actacaaatt gagaggtttt ttgaagacca tgaaaatgtt 1000

 gttgaagtct tatcagactg gacaagagac acagaaaata aaatactatt 1050

 tttggagaaa gaattcagaa ggagtcccag tatatcaagt atctctgctg 1100

 tgatgacaca agaaccctta accagtgggt catgggaata cggatagcca 1150

 agtatgggaa gactttctat gataactacc agcgggctgt ggcaaaggct 1200

 ggacttgcct ctcggtggac aaacttgggg acagtcaatg cagctgcacc 1250

 agctcagcca tctacaggac ctaaaacagg caccacccag cccaatggac 1300

 agattcccca ggctacacat tctgtcagtg ctgttctcca agaggcccag 1350

 agacatgctg aaacatcgaa ggtaaaacca gcaagcagct gacccctata 1400

 agccatgttc taaaccattc acattattcc agtaactgct cttttaaaaa 1450

 gagaaaataa gctgagtgca gtagctcaca cctgtagtcc cggaactttg 1500

 ggaggctgag gcaggaggat cacttgagct tcagtttgag accagactgg 1550

 acaatatagc gagagcttgt ctctactaaa aaaaaa 1586

<210> 3502
<211> 288
<212> PRT
<213> Homo sapien

<400> 3502
 Met Gly Glu Ser Ser Glu Asp Ile Asp Gln Met Phe Ser Thr Leu
   1               5                  10                  15

 Leu Gly Glu Met Asp Leu Leu Thr Gln Ser Leu Gly Val Asp Thr
                  20                  25                  30

 Leu Pro Pro Pro Asp Pro Asn Pro Pro Arg Ala Glu Phe Asn Tyr
                  35                  40                  45

 Ser Val Gly Phe Lys Asp Leu Asn Glu Ser Leu Asn Ala Leu Glu
                  50                  55                  60

 Asp Gln Asp Leu Asp Ala Leu Met Ala Asp Leu Val Ala Asp Ile
                  65                  70                  75

 Ser Glu Ala Glu Gln Arg Thr Ile Gln Ala Gln Lys Glu Ser Leu
                  80                  85                  90

 Gln Asn Gln His His Ser Ala Ser Leu Gln Ala Ser Ile Phe Ser
                  95                 100                 105

 Gly Ala Ala Ser Leu Gly Tyr Gly Thr Asn Val Ala Ala Thr Gly
                 110                 115                 120

 Ile Ser Gln Tyr Glu Asp Asp Leu Pro Pro Pro Pro Ala Asp Pro
                 125                 130                 135

 Val Leu Asp Leu Pro Leu Pro Pro Pro Pro Pro Glu Pro Leu Ser
                 140                 145                 150

 Gln Glu Glu Glu Glu Ala Gln Ala Lys Ala Asp Lys Ile Lys Leu
                 155                 160                 165

 Ala Leu Glu Lys Leu Lys Glu Ala Lys Val Lys Lys Leu Val Val
                 170                 175                 180

 Lys Val His Met Asn Asp Asn Ser Thr Lys Ser Leu Met Val Asp
                 185                 190                 195

 Glu Arg Gln Leu Ala Arg Asp Val Leu Asp Asn Leu Phe Glu Lys
                 200                 205                 210

 Thr His Cys Asp Cys Asn Val Asp Trp Cys Leu Tyr Glu Ile Tyr
                 215                 220                 225

 Pro Glu Leu Gln Ile Glu Arg Phe Phe Glu Asp His Glu Asn Val
                 230                 235                 240

 Val Glu Val Leu Ser Asp Trp Thr Arg Asp Thr Glu Asn Lys Ile
                 245                 250                 255

 Leu Phe Leu Glu Lys Glu Phe Arg Arg Ser Pro Ser Ile Ser Ser
                 260                 265                 270

 Ile Ser Ala Val Met Thr Gln Glu Pro Leu Thr Ser Gly Ser Trp
                 275                 280                 285

 Glu Tyr Gly


<210> 3503
<211> 2844
<212> DNA
<213> Homo sapien

<400> 3503
 acccaaccct gtcattattt cccctccgac tgggccggtg ccatcggaaa 50

 ccggagtgac cagaggaggg acacgcatcc aatttcactg ggctgcaaga 100

 tatcaataag ccttgcctct ttaaactact tatgtacaaa taaaagtgat 150

 ggtgagaacc tggctcagga aatgcagtag caggccatat tgcatccaaa 200

 ggaattactc acagctgtgc tgtgtgcatt ctctgtgggc ctagcaggga 250

 aggggacagc cctgtggcaa tgggcatgac acggatgctc ctggaatgca 300

 gtctcagtga caagttgtgt gtcatccagg agaagcagta tgaagtgatt 350

 atcgtcccaa ctttgttggt tactatcttc ctcatccttc ttggggtcat 400

 cctgtggctt tttatcagag aacaaagaac tcaacagcag cgttctggac 450

 ctcaaggcat tgcccctgtt cctccaccta gggacctaag ctgggaagca 500

 ggacatggag gaaatgtggc tttgccactt aaggagacat ccgtggaaaa 550

 ctttctggga gctaccacac ctgccctggc taagctgcag gtgccgcggg 600

 agcaactctc tgaagttctg gagcagattt gcagtggtag ctgtgggccc 650

 atctttcgag ccaatatgaa cactggggac ccttctaagc ccaagagtgt 700

 tattctcaag gctttaaaag aaccagctgg gctccatgag gtacaagatt 750

 tcttagggcg aatccaattc catcaatacc tggggaaaca caaaaacctg 800

 gtgcagctgg aaggctgctg cactgaaaag ctgccactct atatggtgtt 850

 ggaggatgtg gcccaggggg acctgctcgg ctttctctgg acctgtcggc 900

 gggatgtgat gactatggat ggtcttctct atgatctcac agaaaaacaa 950

 gtatatcaca tcggaaagca ggtccttttg gcgctggaat tcctgcagga 1000

 gaagcatttg ttccatgggg atgtggcagc caggaatatt ctgatgcaaa 1050

 gtgatctcac tgctaagctc tgtggattag gcctggctta tgaagtttac 1100

 acccgagggg ccatctcctc tactcaaacc atacctctca agtggcttgc 1150

 cccagaacgg cttctcctga gacctgctag catcagagca gatgtctggt 1200

 cttttgggat cctgctctat gagatggtga ctctaggagc accaccgtat 1250

 cctgaagtcc ctcctaccag catcctagag catctccaaa gaaggaaaat 1300

 catgaagaga cccagtagct gcacacatac catgtacagt atcatgaagt 1350

 cctgctggcg ctggcgtgag gctgaccgcc cctcacctag agagctgcgc 1400

 ttgcgcctag aagctgccat taaaactgca gatgacgagg ctgtgttaca 1450

 agtaccagag ttggtggtac ctgaactgta tgcagctgtg gccggcatca 1500

 gagtggagag cctcttctac aactatagca tgctttgaag agtctcgggc 1550

 aagaaacatt catgcatgag tatatgttct tggaatcaat tcctctaaga 1600

 acagagaatg gtctttccca gggacacaaa gggagaaatg ggacatggat 1650

 tcttgatctt cctttacaca tttctcggga aatctgaaat gatgctggat 1700

 gggactctac acatcctgag ctaagacata ctgtcagtct cacttctgct 1750

 gtcccagtcc tagaaatcct gggtagaagt ggtggacctg tgcaaaggag 1800

 gttttagaac tctgcagtat ttgttggggc atggcacaaa taagctcatc 1850

 cctcccgtcc gaggctagtt tcctctggaa ccacattttt atctagatga 1900

 aaatttggaa tgaaatgaag gaatagaaat ccaataaaag agttgaaggg 1950

 aaagaaaatt taaggttctt cttgctcagg attacagata tggaccaaca 2000

 cctccttcaa gaaaaggtgg taggacacaa agttcttcag tcctgagccc 2050

 tacatgtggg gttggaggag aactataacg gaaaaacctc tgagtttcac 2100

 cttaggtata gataaaagaa agatggtccc cttttatctg attctgagac 2150

 aggtaaattc tgtttgttac tacgtttaat tagaaggtgg aggagtcatt 2200

 tcatgattaa gaacattcaa catgtattgt tcattaagct agcttcctag 2250

 ttccgattag actaaggaga ctaagcctag agagtcaatg ttagaacagt 2300

 gaaaagaatt ctgtgtgtgt gtgtgtgtgt gtgcacaata aataggaaat 2350

 gtagaaacca agcaagaagg cttagtagct cagtctttaa caagggctag 2400

 aaaagaatgt aatctgatat ggaaggatag cagcttctaa ttttcaatca 2450

 tctgttgata tactgtgaaa cttattttat taaattaata tttattaaat 2500

 ggaaatatgc ttttctggtt tataactact aaaaatatca tagggaggat 2550

 aaaagtaaat aagtgaaagt taatgccaat agaaaaattc aagagataat 2600

 gtacaatgtc agaaaaggga ttctttatgt gtaaatgggg ataataccta 2650

 tttcacaagg ttgttctgag gattgatacg ttttgagtat gtatttgtac 2700

 actatctggc acatatgcgc tcaataaacg tgtttctcct tttaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 2844

<210> 3504
<211> 422
<212> PRT
<213> Homo sapien

<400> 3504
 Met Gly Met Thr Arg Met Leu Leu Glu Cys Ser Leu Ser Asp Lys
   1               5                  10                  15

 Leu Cys Val Ile Gln Glu Lys Gln Tyr Glu Val Ile Ile Val Pro
                  20                  25                  30

 Thr Leu Leu Val Thr Ile Phe Leu Ile Leu Leu Gly Val Ile Leu
                  35                  40                  45

 Trp Leu Phe Ile Arg Glu Gln Arg Thr Gln Gln Gln Arg Ser Gly
                  50                  55                  60

 Pro Gln Gly Ile Ala Pro Val Pro Pro Pro Arg Asp Leu Ser Trp
                  65                  70                  75

 Glu Ala Gly His Gly Gly Asn Val Ala Leu Pro Leu Lys Glu Thr
                  80                  85                  90

 Ser Val Glu Asn Phe Leu Gly Ala Thr Thr Pro Ala Leu Ala Lys
                  95                 100                 105

 Leu Gln Val Pro Arg Glu Gln Leu Ser Glu Val Leu Glu Gln Ile
                 110                 115                 120

 Cys Ser Gly Ser Cys Gly Pro Ile Phe Arg Ala Asn Met Asn Thr
                 125                 130                 135

 Gly Asp Pro Ser Lys Pro Lys Ser Val Ile Leu Lys Ala Leu Lys
                 140                 145                 150

 Glu Pro Ala Gly Leu His Glu Val Gln Asp Phe Leu Gly Arg Ile
                 155                 160                 165

 Gln Phe His Gln Tyr Leu Gly Lys His Lys Asn Leu Val Gln Leu
                 170                 175                 180

 Glu Gly Cys Cys Thr Glu Lys Leu Pro Leu Tyr Met Val Leu Glu
                 185                 190                 195

 Asp Val Ala Gln Gly Asp Leu Leu Gly Phe Leu Trp Thr Cys Arg
                 200                 205                 210

 Arg Asp Val Met Thr Met Asp Gly Leu Leu Tyr Asp Leu Thr Glu
                 215                 220                 225

 Lys Gln Val Tyr His Ile Gly Lys Gln Val Leu Leu Ala Leu Glu
                 230                 235                 240

 Phe Leu Gln Glu Lys His Leu Phe His Gly Asp Val Ala Ala Arg
                 245                 250                 255

 Asn Ile Leu Met Gln Ser Asp Leu Thr Ala Lys Leu Cys Gly Leu
                 260                 265                 270

 Gly Leu Ala Tyr Glu Val Tyr Thr Arg Gly Ala Ile Ser Ser Thr
                 275                 280                 285

 Gln Thr Ile Pro Leu Lys Trp Leu Ala Pro Glu Arg Leu Leu Leu
                 290                 295                 300

 Arg Pro Ala Ser Ile Arg Ala Asp Val Trp Ser Phe Gly Ile Leu
                 305                 310                 315

 Leu Tyr Glu Met Val Thr Leu Gly Ala Pro Pro Tyr Pro Glu Val
                 320                 325                 330

 Pro Pro Thr Ser Ile Leu Glu His Leu Gln Arg Arg Lys Ile Met
                 335                 340                 345

 Lys Arg Pro Ser Ser Cys Thr His Thr Met Tyr Ser Ile Met Lys
                 350                 355                 360

 Ser Cys Trp Arg Trp Arg Glu Ala Asp Arg Pro Ser Pro Arg Glu
                 365                 370                 375

 Leu Arg Leu Arg Leu Glu Ala Ala Ile Lys Thr Ala Asp Asp Glu
                 380                 385                 390

 Ala Val Leu Gln Val Pro Glu Leu Val Val Pro Glu Leu Tyr Ala
                 395                 400                 405

 Ala Val Ala Gly Ile Arg Val Glu Ser Leu Phe Tyr Asn Tyr Ser
                 410                 415                 420

 Met Leu


<210> 3505
<211> 4155
<212> DNA
<213> Homo sapien

<400> 3505
 gggagctggt ggcgcggcgc aggtcccggc cgagtgtggc gcagcagtgg 50

 cggcgcttcc cattcgccat gcgccggggg tgggtgcccg aaggttgcat 100

 gatggaattt gaacattact tcaagaggtt ttgtattttg gattagttaa 150

 ttgggtttgt cctctgctga ctgtttcttc ggatgcattt tttggtgtgc 200

 tcttgaggga ttaaatgcaa agagatcaca ccatggacta caaggaaagc 250

 tgcccaagtg taagcattcc cagctccgat gaacacagag agaaaaagaa 300

 gaggtttact gtttataaag ttctggtttc agtgggaaga agtgaatggt 350

 ttgtcttcag gagatatgca gagtttgata aactttataa cactttaaaa 400

 aaacagtttc ctgctatggc cctgaagatt cctgccaaga gaatatttgg 450

 tgataatttt gatccagatt ttattaaaca aagacgagca ggactaaacg 500

 aattcattca gaacctagtt aggtatccag aactttataa ccatccagat 550

 gtcagagcat tccttcaaat ggacagtcca aaacaccagt cagatccatc 600

 tgaagatgag gatgaaagaa gttctcagaa gctacactct acctcacaga 650

 acatcaacct gggaccgtct ggaaatcctc atgccaaacc aactgacttt 700

 gatttcttaa aagttattgg aaaaggcagc tttggcaagg ttcttcttgc 750

 aaaacggaaa ctggatggaa aattttatgc tgtcaaagtg ttacagaaaa 800

 aaatagttct caacagaaaa gagcaaaaac atattatggc tgaacgtaat 850

 gtgctcttga aaaatgtgaa acatccgttt ttggttggat tgcattattc 900

 cttccaaaca actgaaaagc tttattttgt tctggatttt gttaatggag 950

 gggagctttt tttccactta caaagagaac ggtcctttcc tgagcacaga 1000

 gctaggtttt acgctgctga aattgctagt gcattgggtt acttacattc 1050

 catcaaaata gtatacagag acttgaaacc agaaaatatt cttttggatt 1100

 cagtaggaca tgttgtctta acagattttg ggctttgtaa agaaggaatt 1150

 gctatttctg acaccactac cacattttgt gggacaccag agtatcttgc 1200

 acctgaagta attagaaaac agccctatga caatactgta gattggtggt 1250

 gccttggggc tgttctgtat gaaatgctgt atggattgcc tcctttttat 1300

 tgccgagatg ttgctgaaat gtatgacaat atccttcaca aacccctaag 1350

 tttgaggcca ggagtgagtc ttacagcctg gtccattctg gaagaactcc 1400

 tagaaaaaga caggcaaaat cgacttggtg ccaaggaaga ctttcttgaa 1450

 attcagaatc atcctttttt tgaatcactc agctgggctg accttgtaca 1500

 aaagaagatt ccaccaccat ttaatcctaa tgtggctgga ccagatgata 1550

 tcagaaactt tgacacagca tttacagaag aaacagttcc atattctgtg 1600

 tgtgtatctt ctgactattc tatagtgaat gccagtgtat tggaggcaga 1650

 tgatgcattc gttggtttct cttatgcacc tccttcagaa gacttatttt 1700

 tgtgagcagt ttgccattca gaaaccattg agcaaaataa gtctatagat 1750

 gggactgaaa cttctatttg tgtgaatata ttcaaatatg tataactagt 1800

 gcctcatttt tatatgtaat gatgaaaact atgaaaaaat gtattttctt 1850

 ctatgtgcaa gaaaaatagg gcatttcaaa gagctgtttt gattaaaatt 1900

 tatattcttg tttaataagc ttatttttaa acaatttaaa agctattatt 1950

 cttagcatta acctattttt aaagaaacct tttttgctat tgactgtttt 2000

 ttccctctaa gtttacacta acatctaccc aagatagact gttttttaac 2050

 agtcaatttc agttcagcta acatatatta atacctttgt aactctttgc 2100

 tatggctttt gttatcacac caaaactatg caattggtac atggttgttt 2150

 aagaagaaac cgtatttttc catgataaat cactgtttga aatatttggt 2200

 tcatggtatg atcgaaatgt aaaagcataa ttaacacatt ggctgctagt 2250

 taacaattgg aataacttta ttctgcagat catttaagaa gtaacaggcc 2300

 gggcgcggtg gctcacgcct gtaatcccag cactttggga ggctgaggcg 2350

 ggcagatcac ctgaggtcag gagttggaga ccagcctgac caacatggac 2400

 aaaccccgtc tctactaaaa atacaaaatt ggcagggtgt ggtggcacat 2450

 gcctataatc ccagctactt gggaggctaa ggcaggagaa tcgcttgaac 2500

 ccgggaggcg gaggttgcag tgagccgaga tcgcaccatt gcactcctgc 2550

 ctgggcaaca agagtgaaac tccatctcca aaaaaaaaaa gaaaaagtaa 2600

 caaaaggaaa ttatttgttt ttgaaatacc agttcaactt tgtggattat 2650

 ttttcctctg aaggaaaaga aaaggcttaa tggttaggat ttttaagtat 2700

 tcccaaagat ctgaagggta ataaaatgta ctggattttt taaggtggta 2750

 ccaaaaatga atgtctgtca tatatttata ttacaaatac attatattta 2800

 tgttctattc atcttttgaa tgtttagtat gctattaagt cattctgaat 2850

 ctttgtattt gcttttgcaa ataggtattt caaagctctt ttcctaactg 2900

 gttaagtaaa ataaaaaatt gagctttcta gaatatttgc ctaattggga 2950

 attaaaaagt aaaataatag gccaggcatg gtggctcatg cctataagca 3000

 ccctgggagg ccgaggcagg cagattattt gagctcagga gtttgagacc 3050

 atcctgggca acatggcgaa accctatctc tacaaaaaat acaaaaatta 3100

 gccagacatg gtggcacatg cctttagtcc cagctactct ggaggctgaa 3150

 gttggaggat ggcttgagcc cacgagatgg aagttgcagt gaactgaaat 3200

 tgtgccactg cacttttcag cctgggtgcc acagcgagac cctagttaag 3250

 agaaaaaaaa agtaaaaaca aattgtgggt caaagtaaat gtatacagtt 3300

 ttattacaat gtaacaaaag ttgaaaatca ggcagatgtg tattcagtat 3350

 ccaattcaat atatcttaga aaaagcacag gaaacagacc ttaaaattgt 3400

 aacctaccaa ctaacttaca tgcttataaa agtaaaggag aataactggc 3450

 cgggcacggt ggctcatgcc tataaaattc cagcactttg ggaggccaag 3500

 gcaggaggat cacttgagcc tatgagttca agaccagcct aggcaatgta 3550

 gtgacacctc atttctattt attttaaaaa aaagagagag taactacaga 3600

 agaactttaa aaaataaaaa ataagcttac cttggattct tggcttagag 3650

 tagaggtttt ttttaagtta tggaggaaac atttttgtaa aagtttaatg 3700

 acccacttta gatgctccaa gaacaagcat cccttccatg tatgtcttga 3750

 gaaagaaatc acagaagcat ttctcaccaa tactctttgg cttaaaatgt 3800

 tcagcagaat tgggcagtgg gggtgacttt tcttatatta ataatattta 3850

 catccaatac actgaatctt cctttagagg taagacttta atatctatac 3900

 tgtaaatatt tggtttattt ggcactactg taagttttgt ttttcacaaa 3950

 gctcttatta tgaagcaaaa taaaaattct agtttcttgt atgatttttt 4000

 gtactcattc attcctgtta agctgccaaa aattaaagtg caatattgta 4050

 tatttttaag aacaaattta aaatagaatt ttgatgtttc tcagatcaca 4100

 agaaatacaa atctatatag tataataaaa tcagcaaaaa gatcaaaaaa 4150

 aaaaa 4155

<210> 3506
<211> 429
<212> PRT
<213> Homo sapien

<400> 3506
 Met Ala Leu Lys Ile Pro Ala Lys Arg Ile Phe Gly Asp Asn Phe
   1               5                  10                  15

 Asp Pro Asp Phe Ile Lys Gln Arg Arg Ala Gly Leu Asn Glu Phe
                  20                  25                  30

 Ile Gln Asn Leu Val Arg Tyr Pro Glu Leu Tyr Asn His Pro Asp
                  35                  40                  45

 Val Arg Ala Phe Leu Gln Met Asp Ser Pro Lys His Gln Ser Asp
                  50                  55                  60

 Pro Ser Glu Asp Glu Asp Glu Arg Ser Ser Gln Lys Leu His Ser
                  65                  70                  75

 Thr Ser Gln Asn Ile Asn Leu Gly Pro Ser Gly Asn Pro His Ala
                  80                  85                  90

 Lys Pro Thr Asp Phe Asp Phe Leu Lys Val Ile Gly Lys Gly Ser
                  95                 100                 105

 Phe Gly Lys Val Leu Leu Ala Lys Arg Lys Leu Asp Gly Lys Phe
                 110                 115                 120

 Tyr Ala Val Lys Val Leu Gln Lys Lys Ile Val Leu Asn Arg Lys
                 125                 130                 135

 Glu Gln Lys His Ile Met Ala Glu Arg Asn Val Leu Leu Lys Asn
                 140                 145                 150

 Val Lys His Pro Phe Leu Val Gly Leu His Tyr Ser Phe Gln Thr
                 155                 160                 165

 Thr Glu Lys Leu Tyr Phe Val Leu Asp Phe Val Asn Gly Gly Glu
                 170                 175                 180

 Leu Phe Phe His Leu Gln Arg Glu Arg Ser Phe Pro Glu His Arg
                 185                 190                 195

 Ala Arg Phe Tyr Ala Ala Glu Ile Ala Ser Ala Leu Gly Tyr Leu
                 200                 205                 210

 His Ser Ile Lys Ile Val Tyr Arg Asp Leu Lys Pro Glu Asn Ile
                 215                 220                 225

 Leu Leu Asp Ser Val Gly His Val Val Leu Thr Asp Phe Gly Leu
                 230                 235                 240

 Cys Lys Glu Gly Ile Ala Ile Ser Asp Thr Thr Thr Thr Phe Cys
                 245                 250                 255

 Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val Ile Arg Lys Gln Pro
                 260                 265                 270

 Tyr Asp Asn Thr Val Asp Trp Trp Cys Leu Gly Ala Val Leu Tyr
                 275                 280                 285

 Glu Met Leu Tyr Gly Leu Pro Pro Phe Tyr Cys Arg Asp Val Ala
                 290                 295                 300

 Glu Met Tyr Asp Asn Ile Leu His Lys Pro Leu Ser Leu Arg Pro
                 305                 310                 315

 Gly Val Ser Leu Thr Ala Trp Ser Ile Leu Glu Glu Leu Leu Glu
                 320                 325                 330

 Lys Asp Arg Gln Asn Arg Leu Gly Ala Lys Glu Asp Phe Leu Glu
                 335                 340                 345

 Ile Gln Asn His Pro Phe Phe Glu Ser Leu Ser Trp Ala Asp Leu
                 350                 355                 360

 Val Gln Lys Lys Ile Pro Pro Pro Phe Asn Pro Asn Val Ala Gly
                 365                 370                 375

 Pro Asp Asp Ile Arg Asn Phe Asp Thr Ala Phe Thr Glu Glu Thr
                 380                 385                 390

 Val Pro Tyr Ser Val Cys Val Ser Ser Asp Tyr Ser Ile Val Asn
                 395                 400                 405

 Ala Ser Val Leu Glu Ala Asp Asp Ala Phe Val Gly Phe Ser Tyr
                 410                 415                 420

 Ala Pro Pro Ser Glu Asp Leu Phe Leu
                 425

<210> 3507
<211> 4485
<212> DNA
<213> Homo sapien

<400> 3507
 gtagacagat ccaggctcac cagtcctgtg ccactgggct tttggcgttc 50

 tgcacaaggc ctacccgcag atgccatgcc tgctccccca gcctaatggg 100

 ctttgatggg ggaagagggt ggttcagcct ctcacgatga ggaggaaaga 150

 gcaagtgtcc tcctcggaca ttctccgggt tgtgaaatgt gctcgcagga 200

 ggcttttcag gcacagagga gccagctggt cgagctgctg gtctcagggt 250

 ccctggaagg cttcgagagt gtcctggact ggctgctgtc ctgggaggtc 300

 ctctcctggg aggactacga gggcttccac ctcctgggcc agcctctctc 350

 ccacttggcc aggcgccttc tggacaccgt ctggaataag ggtacttggg 400

 cctgtcagaa gctcatcgcg gctgcccaag aagcccaggc cgacagccag 450

 tcccccaagc tgcatggctg ctgggacccc cactcgctcc acccagcccg 500

 agacctgcag agtcaccggc cagccattgt caggaggctc cacagccatg 550

 tggagaacat gctggacctg gcatgggagc ggggtttcgt cagccagtat 600

 gaatgtgatg aaatcaggtt gccgatcttc acaccgtccc agagggcaag 650

 aaggctgctt gatcttgcca cggtgaaagc gaatggattg gctgccttcc 700

 ttctacaaca tgttcaggaa ttaccagtcc cattggccct gcctttggaa 750

 gctgccacat gcaagaagta tatggccaag ctgaggacca cggtgtctgc 800

 tcagtctcgc ttcctcagta cctatgatgg agcagagacg ctctgcctgg 850

 aggacatata cacagagaat gtcctggagg tctgggcaga tgtgggcatg 900

 gctggacccc cgcagaagag cccagccacc ctgggcctgg aggagctctt 950

 cagcacccct ggccacctca atgacgatgc ggacactgtg ctggtggtgg 1000

 gtgaggcggg cagtggcaag agcacgctcc tgcagcggct gcacttgctg 1050

 tgggctgcag ggcaagactt ccaggaattt ctctttgtct tcccattcag 1100

 ctgccggcag ctgcagtgca tggccaaacc actctctgtg cggactctac 1150

 tctttgagca ctgctgttgg cctgatgttg gtcaagaaga catcttccag 1200

 ttactccttg accaccctga ccgtgtcctg ttaacctttg atggctttga 1250

 cgagttcaag ttcaggttca cggatcgtga acgccactgc tccccgaccg 1300

 accccacctc tgtccagacc ctgctcttca accttctgca gggcaacctg 1350

 ctgaagaatg cccgcaaggt ggtgaccagc cgtccggccg ctgtgtcggc 1400

 gttcctcagg aagtacatcc gcaccgagtt caacctcaag ggcttctctg 1450

 aacagggcat cgagctgtac ctgaggaagc gccatcatga gcccggggtg 1500

 gcggaccgcc tcatccgcct gctccaagag acctcagccc tgcacggttt 1550

 gtgccacctg cctgtcttct catggatggt gtccaaatgc caccaggaac 1600

 tgttgctgca ggaggggggg tccccaaaga ccactacaga tatgtacctg 1650

 ctgattctgc agcattttct gctgcatgcc acccccccag actcagcttc 1700

 ccaaggtctg ggacccagtc ttcttcgggg ccgcctcccc accctcctgc 1750

 acctgggcag actggctctg tggggcctgg gcatgtgctg ctacgtgttc 1800

 tcagcccagc agctccaggc agcacaggtc agccctgatg acatttctct 1850

 tggcttcctg gtgcgtgcca aaggtgtcgt gccagggagt acggcgcccc 1900

 tggaattcct tcacatcact ttccagtgct tctttgccgc gttctacctg 1950

 gcactcagtg ctgatgtgcc accagctttg ctcagacacc tcttcaattg 2000

 tggcaggcca ggcaactcac caatggccag gctcctgccc acgatgtgca 2050

 tccaggcctc ggagggaaag gacagcagcg tggcagcttt gctgcagaag 2100

 gccgagccgc acaaccttca gatcacagca gccttcctgg cagggctgtt 2150

 gtcccgggag cactggggcc tgctggctga gtgccagaca tctgagaagg 2200

 ccctgctccg gcgccaggcc tgtgcccgct ggtgtctggc ccgcagcctc 2250

 cgcaagcact tccactccat cccgccagct gcaccgggtg aggccaagag 2300

 cgtgcatgcc atgcccgggt tcatctggct catccggagc ctgtacgaga 2350

 tgcaggagga gcggctggct cggaaggctg cacgtggcct gaatgttggg 2400

 cacctcaagt tgacattttg cagtgtgggc cccactgagt gtgctgccct 2450

 ggcctttgtg ctgcagcacc tccggcggcc cgtggccctg cagctggact 2500

 acaactctgt gggtgacatt ggcgtggagc agctgctgcc ttgccttggt 2550

 gtctgcaagg ctctgtattt gcgcgataac aatatctcag accgaggcat 2600

 ctgcaagctc attgaatgtg ctcttcactg cgagcaattg cagaagttag 2650

 ctctattcaa caacaaattg actgacggct gtgcacactc catggctaag 2700

 ctccttgcat gcaggcagaa cttcttggca ttgaggctgg ggaataacta 2750

 catcactgcc gcgggagccc aagtgctggc cgaggggctc cgaggcaaca 2800

 cctccttgca gttcctggga ttctggggca acagagtggg tgacgagggg 2850

 gcccaggccc tggctgaagc cttgggtgat caccagagct tgaggtggct 2900

 cagcctggtg gggaacaaca ttggcagtgt gggtgcccaa gccttggcac 2950

 tgatgctggc aaagaacgtc atgctagaag aactctgcct ggaggagaac 3000

 catctccagg atgaaggtgt atgttctctc gcagaaggac tgaagaaaaa 3050

 ttcaagtttg aaaatcctga agttgtccaa taactgcatc acctacctag 3100

 gggcagaagc cctcctgcag gcccttgaaa ggaatgacac catcctggaa 3150

 gtctggctcc gagggaacac tttctctcta gaggaggttg acaagctcgg 3200

 ctgcagggac accagactct tgctttgaag tctccgggag gatgttcgtc 3250

 tcagtttgtt tgtgagcagg ctgtgagttt gggccccaga ggctgggtga 3300

 catgtgttgg cagcctcttc aaaatgagcc ctgtcctgcc taaggctgaa 3350

 cttgttttct gggaacacca taggtcacct ttattctggc agaggaggga 3400

 gcatcagtgc cctccaggat agacttttcc caagcctact tttgccattg 3450

 acttcttccc aagattcaat cccaggatgt acaaggacag cccctcctcc 3500

 atagtatggg actggcctct gctgatcctc ccaggcttcc gtgtgggtca 3550

 gtggggccca tggatgtgct tgttaactga gtgccttttg gtggagaggc 3600

 ccggcctctc acaaaagacc ccttaccact gctctgatga agaggagtac 3650

 acagaacaca taattcagga agcagctttc cccatgtctc gactcatcca 3700

 tccaggccat tccccgtctc tggttcctcc cctcctcctg gactcctgca 3750

 cacgctcctt cctctgaggc tgaaattcag aatattagtg acctcagctt 3800

 tgatatttca cttacagcac ccccaaccct ggcacccagg gtgggaaggg 3850

 ctacacctta gcctgccctc ctttccggtg tttaagacat ttttggaagg 3900

 ggacacgtga cagccgtttg ttccccaaga cattctaggt ttgcaagaaa 3950

 aatatgacca cactccagct gggatcacat gtggactttt atttccagtg 4000

 aaatcagtta ctcttcagtt aagcctttgg aaacagctcg actttaaaaa 4050

 gctccaaatg cagctttaaa aaattaatct gggccagaat ttcaaacggc 4100

 ctcactaggc ttctggttga tgcctgtgaa ctgaactctg acaacagact 4150

 tctgaaatag acccacaaga ggcagttcca tttcatttgt gccagaatgc 4200

 tttaggatgt acagttatgg attgaaagtt tacaggaaaa aaaattaggc 4250

 cgttccttca aagcaaatgt cttcctggat tattcaaaat gatgtatgtt 4300

 gaagcctttg taaattgtca gatgctgtgc aaatgttatt attttaaaca 4350

 ttatgatgtg tgaaaactgg ttaatattta taggtcactt tgttttactg 4400

 tcttaagttt atactcttat agacaacatg gccgtgaact ttatgctgta 4450

 aataatcaga ggggaataaa ctgttgagtc aaaac 4485

<210> 3508
<211> 1040
<212> PRT
<213> Homo sapien

<400> 3508
 Met Gly Glu Glu Gly Gly Ser Ala Ser His Asp Glu Glu Glu Arg
   1               5                  10                  15

 Ala Ser Val Leu Leu Gly His Ser Pro Gly Cys Glu Met Cys Ser
                  20                  25                  30

 Gln Glu Ala Phe Gln Ala Gln Arg Ser Gln Leu Val Glu Leu Leu
                  35                  40                  45

 Val Ser Gly Ser Leu Glu Gly Phe Glu Ser Val Leu Asp Trp Leu
                  50                  55                  60

 Leu Ser Trp Glu Val Leu Ser Trp Glu Asp Tyr Glu Gly Phe His
                  65                  70                  75

 Leu Leu Gly Gln Pro Leu Ser His Leu Ala Arg Arg Leu Leu Asp
                  80                  85                  90

 Thr Val Trp Asn Lys Gly Thr Trp Ala Cys Gln Lys Leu Ile Ala
                  95                 100                 105

 Ala Ala Gln Glu Ala Gln Ala Asp Ser Gln Ser Pro Lys Leu His
                 110                 115                 120

 Gly Cys Trp Asp Pro His Ser Leu His Pro Ala Arg Asp Leu Gln
                 125                 130                 135

 Ser His Arg Pro Ala Ile Val Arg Arg Leu His Ser His Val Glu
                 140                 145                 150

 Asn Met Leu Asp Leu Ala Trp Glu Arg Gly Phe Val Ser Gln Tyr
                 155                 160                 165

 Glu Cys Asp Glu Ile Arg Leu Pro Ile Phe Thr Pro Ser Gln Arg
                 170                 175                 180

 Ala Arg Arg Leu Leu Asp Leu Ala Thr Val Lys Ala Asn Gly Leu
                 185                 190                 195

 Ala Ala Phe Leu Leu Gln His Val Gln Glu Leu Pro Val Pro Leu
                 200                 205                 210

 Ala Leu Pro Leu Glu Ala Ala Thr Cys Lys Lys Tyr Met Ala Lys
                 215                 220                 225

 Leu Arg Thr Thr Val Ser Ala Gln Ser Arg Phe Leu Ser Thr Tyr
                 230                 235                 240

 Asp Gly Ala Glu Thr Leu Cys Leu Glu Asp Ile Tyr Thr Glu Asn
                 245                 250                 255

 Val Leu Glu Val Trp Ala Asp Val Gly Met Ala Gly Pro Pro Gln
                 260                 265                 270

 Lys Ser Pro Ala Thr Leu Gly Leu Glu Glu Leu Phe Ser Thr Pro
                 275                 280                 285

 Gly His Leu Asn Asp Asp Ala Asp Thr Val Leu Val Val Gly Glu
                 290                 295                 300

 Ala Gly Ser Gly Lys Ser Thr Leu Leu Gln Arg Leu His Leu Leu
                 305                 310                 315

 Trp Ala Ala Gly Gln Asp Phe Gln Glu Phe Leu Phe Val Phe Pro
                 320                 325                 330

 Phe Ser Cys Arg Gln Leu Gln Cys Met Ala Lys Pro Leu Ser Val
                 335                 340                 345

 Arg Thr Leu Leu Phe Glu His Cys Cys Trp Pro Asp Val Gly Gln
                 350                 355                 360

 Glu Asp Ile Phe Gln Leu Leu Leu Asp His Pro Asp Arg Val Leu
                 365                 370                 375

 Leu Thr Phe Asp Gly Phe Asp Glu Phe Lys Phe Arg Phe Thr Asp
                 380                 385                 390

 Arg Glu Arg His Cys Ser Pro Thr Asp Pro Thr Ser Val Gln Thr
                 395                 400                 405

 Leu Leu Phe Asn Leu Leu Gln Gly Asn Leu Leu Lys Asn Ala Arg
                 410                 415                 420

 Lys Val Val Thr Ser Arg Pro Ala Ala Val Ser Ala Phe Leu Arg
                 425                 430                 435

 Lys Tyr Ile Arg Thr Glu Phe Asn Leu Lys Gly Phe Ser Glu Gln
                 440                 445                 450

 Gly Ile Glu Leu Tyr Leu Arg Lys Arg His His Glu Pro Gly Val
                 455                 460                 465

 Ala Asp Arg Leu Ile Arg Leu Leu Gln Glu Thr Ser Ala Leu His
                 470                 475                 480

 Gly Leu Cys His Leu Pro Val Phe Ser Trp Met Val Ser Lys Cys
                 485                 490                 495

 His Gln Glu Leu Leu Leu Gln Glu Gly Gly Ser Pro Lys Thr Thr
                 500                 505                 510

 Thr Asp Met Tyr Leu Leu Ile Leu Gln His Phe Leu Leu His Ala
                 515                 520                 525

 Thr Pro Pro Asp Ser Ala Ser Gln Gly Leu Gly Pro Ser Leu Leu
                 530                 535                 540

 Arg Gly Arg Leu Pro Thr Leu Leu His Leu Gly Arg Leu Ala Leu
                 545                 550                 555

 Trp Gly Leu Gly Met Cys Cys Tyr Val Phe Ser Ala Gln Gln Leu
                 560                 565                 570

 Gln Ala Ala Gln Val Ser Pro Asp Asp Ile Ser Leu Gly Phe Leu
                 575                 580                 585

 Val Arg Ala Lys Gly Val Val Pro Gly Ser Thr Ala Pro Leu Glu
                 590                 595                 600

 Phe Leu His Ile Thr Phe Gln Cys Phe Phe Ala Ala Phe Tyr Leu
                 605                 610                 615

 Ala Leu Ser Ala Asp Val Pro Pro Ala Leu Leu Arg His Leu Phe
                 620                 625                 630

 Asn Cys Gly Arg Pro Gly Asn Ser Pro Met Ala Arg Leu Leu Pro
                 635                 640                 645

 Thr Met Cys Ile Gln Ala Ser Glu Gly Lys Asp Ser Ser Val Ala
                 650                 655                 660

 Ala Leu Leu Gln Lys Ala Glu Pro His Asn Leu Gln Ile Thr Ala
                 665                 670                 675

 Ala Phe Leu Ala Gly Leu Leu Ser Arg Glu His Trp Gly Leu Leu
                 680                 685                 690

 Ala Glu Cys Gln Thr Ser Glu Lys Ala Leu Leu Arg Arg Gln Ala
                 695                 700                 705

 Cys Ala Arg Trp Cys Leu Ala Arg Ser Leu Arg Lys His Phe His
                 710                 715                 720

 Ser Ile Pro Pro Ala Ala Pro Gly Glu Ala Lys Ser Val His Ala
                 725                 730                 735

 Met Pro Gly Phe Ile Trp Leu Ile Arg Ser Leu Tyr Glu Met Gln
                 740                 745                 750

 Glu Glu Arg Leu Ala Arg Lys Ala Ala Arg Gly Leu Asn Val Gly
                 755                 760                 765

 His Leu Lys Leu Thr Phe Cys Ser Val Gly Pro Thr Glu Cys Ala
                 770                 775                 780

 Ala Leu Ala Phe Val Leu Gln His Leu Arg Arg Pro Val Ala Leu
                 785                 790                 795

 Gln Leu Asp Tyr Asn Ser Val Gly Asp Ile Gly Val Glu Gln Leu
                 800                 805                 810

 Leu Pro Cys Leu Gly Val Cys Lys Ala Leu Tyr Leu Arg Asp Asn
                 815                 820                 825

 Asn Ile Ser Asp Arg Gly Ile Cys Lys Leu Ile Glu Cys Ala Leu
                 830                 835                 840

 His Cys Glu Gln Leu Gln Lys Leu Ala Leu Phe Asn Asn Lys Leu
                 845                 850                 855

 Thr Asp Gly Cys Ala His Ser Met Ala Lys Leu Leu Ala Cys Arg
                 860                 865                 870

 Gln Asn Phe Leu Ala Leu Arg Leu Gly Asn Asn Tyr Ile Thr Ala
                 875                 880                 885

 Ala Gly Ala Gln Val Leu Ala Glu Gly Leu Arg Gly Asn Thr Ser
                 890                 895                 900

 Leu Gln Phe Leu Gly Phe Trp Gly Asn Arg Val Gly Asp Glu Gly
                 905                 910                 915

 Ala Gln Ala Leu Ala Glu Ala Leu Gly Asp His Gln Ser Leu Arg
                 920                 925                 930

 Trp Leu Ser Leu Val Gly Asn Asn Ile Gly Ser Val Gly Ala Gln
                 935                 940                 945

 Ala Leu Ala Leu Met Leu Ala Lys Asn Val Met Leu Glu Glu Leu
                 950                 955                 960

 Cys Leu Glu Glu Asn His Leu Gln Asp Glu Gly Val Cys Ser Leu
                 965                 970                 975

 Ala Glu Gly Leu Lys Lys Asn Ser Ser Leu Lys Ile Leu Lys Leu
                 980                 985                 990

 Ser Asn Asn Cys Ile Thr Tyr Leu Gly Ala Glu Ala Leu Leu Gln
                 995                1000                1005

 Ala Leu Glu Arg Asn Asp Thr Ile Leu Glu Val Trp Leu Arg Gly
                1010                1015                1020

 Asn Thr Phe Ser Leu Glu Glu Val Asp Lys Leu Gly Cys Arg Asp
                1025                1030                1035

 Thr Arg Leu Leu Leu
                1040

<210> 3509
<211> 1842
<212> DNA
<213> Homo sapien

<400> 3509
 gcgcgccacg gcaggaaagg gcggtcctgc gctgtggccc acgctcgctc 50

 ccgctgtcgg actctgggcc tggaccgcgc gtggccggcg ccaaaagcga 100

 gaggcatgag cgcgcgcccg ggccagtgaa ctgctcgggg atggactgcg 150

 gctcggtcgg cggccagagg acccagcgcc tgcccggccg ccagcggctt 200

 ctcttcttgc ccgtgggcct cagcggaaga ccgggcggca gcgaaacctc 250

 agcacgccgc tgcccctctg cgctctccga cggtctgggg gcgctgcgcc 300

 ctcgcgcccc ggcggcccgc ggcggcgtgt cacgtgcctc accgctgctc 350

 ctcctcctgc tagtgccctc cccgcgcttg gccgccgcag ccccgcgccg 400

 gcagctcggg gactgggagc gctcgcgcct cgggtatgcc gcacccccgg 450

 ccgggcgcag cggcgcgtgg aggtgctcac cgggcgtcgc cgctgccgcc 500

 ggcgcccttc cccagtacca cggcccggcg cctgcactcg tttcctgcag 550

 gagagagcta agcttgtctg ctggatccct gcagctggag cgcaaaagga 600

 gagatttcac ctcttctggg agcaggaaac tctacttcga cactcatgcc 650

 ttagtgtgct tactggaaga caatgaatct cactctttca tccaggctgg 700

 agtgcagtgg cacagtcttg gcctactgca acccccacct cccggtttca 750

 agcgatcctc ccacctcatc ctcctgagta gctgggatta caggcatgca 800

 ccaccacacc tggataattt ttctgtattt ttactagaga cggggtttca 850

 ccatgttggc caggctggtc tcaaactgct gacctcaagt gatccaccca 900

 ccttggcctc ctaaagtgct gggattacag gcgtgaacca ctgtgtccag 950

 ttgccaaacc taattatgtt taaacatgaa ctcttttttt aattaaaatt 1000

 ttttaaaatt ttatttacat taaaatggag atgggatcac tatgttgccc 1050

 atgctggttc tgaactcctg ggctcaaaga tcctcccgcc ttggtctccc 1100

 agagtgttag gattacaggc gtgagccacc acacccagcc agtgaactct 1150

 tcttaataaa actttaaaat ttggcaaaag tttagtttga gtttttaaaa 1200

 actaggaaga cagacgagaa aaaagaaaac agagtcagag ctaaacaatg 1250

 ttaacatttt gggtttgcta ctcaacaagc agaaatcatt gtgtctgcat 1300

 tggtcaagat cctggaggcc aacatggaca tcgtctacaa agatatggtc 1350

 accaagatgc agcaggaaat cacttttcag caagtaatgt ctcagattgc 1400

 gaatgtgaaa aaggatatga ttattttgga gaagagtgaa ttttcagccc 1450

 tcagagcaga aaatgagaaa ataaaactcg aactacatca gttaaaacaa 1500

 caagtaatgg atgaagtgat caaagtccga acagatacca aattagactt 1550

 caacctagaa aagagcagag taaaagaatt gtattcattg aacgaaaaga 1600

 agctgctgga attgagaaca gaaatagtgg cattgcatgc ccagcaagat 1650

 cgggccctta cccagacaga caggaagatc gaaactgagg ttgctggcct 1700

 caaaaccatg cttgagtcac acaagcttga taatattaaa tatttagcag 1750

 ggtctatatt tacgtgccta acagtagctc tgggatttta tcgcctgtgg 1800

 atctaataaa gtgtctattt aaagtgaaaa aaaaaaaaaa aa 1842

<210> 3510
<211> 257
<212> PRT
<213> Homo sapien

<400> 3510
 Met Asp Cys Gly Ser Val Gly Gly Gln Arg Thr Gln Arg Leu Pro
   1               5                  10                  15

 Gly Arg Gln Arg Leu Leu Phe Leu Pro Val Gly Leu Ser Gly Arg
                  20                  25                  30

 Pro Gly Gly Ser Glu Thr Ser Ala Arg Arg Cys Pro Ser Ala Leu
                  35                  40                  45

 Ser Asp Gly Leu Gly Ala Leu Arg Pro Arg Ala Pro Ala Ala Arg
                  50                  55                  60

 Gly Gly Val Ser Arg Ala Ser Pro Leu Leu Leu Leu Leu Leu Val
                  65                  70                  75

 Pro Ser Pro Arg Leu Ala Ala Ala Ala Pro Arg Arg Gln Leu Gly
                  80                  85                  90

 Asp Trp Glu Arg Ser Arg Leu Gly Tyr Ala Ala Pro Pro Ala Gly
                  95                 100                 105

 Arg Ser Gly Ala Trp Arg Cys Ser Pro Gly Val Ala Ala Ala Ala
                 110                 115                 120

 Gly Ala Leu Pro Gln Tyr His Gly Pro Ala Pro Ala Leu Val Ser
                 125                 130                 135

 Cys Arg Arg Glu Leu Ser Leu Ser Ala Gly Ser Leu Gln Leu Glu
                 140                 145                 150

 Arg Lys Arg Arg Asp Phe Thr Ser Ser Gly Ser Arg Lys Leu Tyr
                 155                 160                 165

 Phe Asp Thr His Ala Leu Val Cys Leu Leu Glu Asp Asn Glu Ser
                 170                 175                 180

 His Ser Phe Ile Gln Ala Gly Val Gln Trp His Ser Leu Gly Leu
                 185                 190                 195

 Leu Gln Pro Pro Pro Pro Gly Phe Lys Arg Ser Ser His Leu Ile
                 200                 205                 210

 Leu Leu Ser Ser Trp Asp Tyr Arg His Ala Pro Pro His Leu Asp
                 215                 220                 225

 Asn Phe Ser Val Phe Leu Leu Glu Thr Gly Phe His His Val Gly
                 230                 235                 240

 Gln Ala Gly Leu Lys Leu Leu Thr Ser Ser Asp Pro Pro Thr Leu
                 245                 250                 255

 Ala Ser


<210> 3511
<211> 1960
<212> DNA
<213> Homo sapien

<400> 3511
 gccgtcatct ctaagaaaca accataccac tgaatgctac tgtgtactta 50

 caaaccacac tcatattcgt cacgtcattt catcttcacc cccacctcca 100

 aatgaggctt gaaatgagat gagatgttcc tccctcccct ttcaaccatg 150

 gacctcacac tgtggacttc ctcttagagc ctctgagtta ggtacccaag 200

 ccaaggcaca atgtccctgc cccccataag actgcccagc ccctatggct 250

 ctgatcggct ggtacagcta gcagccaggc tccggccagc actctgtgat 300

 actctgatca ccgtagggag ccaggagttc cccgcccaca gcctggtgct 350

 agcaggtgtc agccagcagc tgggccgcag gggccagtgg gctctgggag 400

 aaggcatcag cccttctacc tttgcccagc tcctgaactt tgtgtatggg 450

 gagagtgtag agctgcagcc tggagagcta aggccccttc aggaggcggc 500

 cagggccttg ggagtgcagt ccctggaaga ggcatgctgg agggctcgag 550

 gggacagggc taaaaagcca gatccaggcc tgaagaaaca tcaggaggag 600

 ccagagaaac cctcaaggaa tcctgagaga gaactggggg accctggaga 650

 gaagcagaaa ccagaacagg tttctagaac tggtgggaga gaacaggaga 700

 tgttgcacaa gcactcgcca ccaagaggca gacccgagat ggcaggagca 750

 acgcaggagg ctcagcagga acagaccagg tcaaaggaga aacgcctcca 800

 agcccctgtt ggccaaaggg gagcagatgg gaagcatgga gtgctcacgt 850

 ggttgaggga aaatccaggg ggctctgagg aaagtctgcg caagctccct 900

 ggcccccttc ccccagcagg ctccctgcaa accagcgtca cccctaggcc 950

 ctcgtgggct gaggcccctt ggttggtggg gggccagcct gccctgtgga 1000

 gcatcctgct gatgccgccc agatatggca ttcccttcta ccatagcacc 1050

 cccaccactg gagcctggca ggaggtctgg cgggaacaga ggatcccact 1100

 gtccctaaat gcccccaaag ggctctggag ccagaaccag ttggcctcct 1150

 ccagccctac cccaggttcc ctcccccagg gccccgcaca gctcagccct 1200

 ggggagatgg aagagtctga tcaggggcac acaggcgcac ttgcaacctg 1250

 tgcgggtcat gaggacaagg caggctgccc acctcgcccg caccctcccc 1300

 cggcccctcc tgctcggtct cggccctatg cgtgctctgt ctgtggaaag 1350

 aggttttcac tcaagcatca gatggagacg cactaccgag tccacacagg 1400

 agagaagccc ttctcctgta gcctttgtcc tcagcgctcc cgggacttct 1450

 cggccatgac caagcacctg cggacacacg gggccgctcc gtaccgctgc 1500

 tccctgtgcg gggccggctg tcccagcctg gcctccatgc aggcgcacat 1550

 gcgcggtcac tcgcccagcc aactcccgcc cggatggacc atccgctcca 1600

 ccttcctcta ctcctcctcg aggccgtctc ggccctcgac ctctccctgt 1650

 tgtccttctt cctccaccac ctgacggggt gtcggtagcg tcttagccaa 1700

 gagtccaatt aaagaacgaa aagcgggccg gctcggcttc tgacctggca 1750

 ccgctgctac ggcggcctag caaattccgc cccagaagcg ccccaggaag 1800

 ggcgccgagt gccctctcct ggacgatcgc gggtcgcaga agcccaggcc 1850

 agcgagccct acagagtgag gacactgaag tgtgcaggag cgaaggttaa 1900

 cagtagggga gattgtcgat ctcatcacca taataaagag tttcctgtgc 1950

 cctcccttca 1960

<210> 3512
<211> 487
<212> PRT
<213> Homo sapien

<400> 3512
 Met Ser Leu Pro Pro Ile Arg Leu Pro Ser Pro Tyr Gly Ser Asp
   1               5                  10                  15

 Arg Leu Val Gln Leu Ala Ala Arg Leu Arg Pro Ala Leu Cys Asp
                  20                  25                  30

 Thr Leu Ile Thr Val Gly Ser Gln Glu Phe Pro Ala His Ser Leu
                  35                  40                  45

 Val Leu Ala Gly Val Ser Gln Gln Leu Gly Arg Arg Gly Gln Trp
                  50                  55                  60

 Ala Leu Gly Glu Gly Ile Ser Pro Ser Thr Phe Ala Gln Leu Leu
                  65                  70                  75

 Asn Phe Val Tyr Gly Glu Ser Val Glu Leu Gln Pro Gly Glu Leu
                  80                  85                  90

 Arg Pro Leu Gln Glu Ala Ala Arg Ala Leu Gly Val Gln Ser Leu
                  95                 100                 105

 Glu Glu Ala Cys Trp Arg Ala Arg Gly Asp Arg Ala Lys Lys Pro
                 110                 115                 120

 Asp Pro Gly Leu Lys Lys His Gln Glu Glu Pro Glu Lys Pro Ser
                 125                 130                 135

 Arg Asn Pro Glu Arg Glu Leu Gly Asp Pro Gly Glu Lys Gln Lys
                 140                 145                 150

 Pro Glu Gln Val Ser Arg Thr Gly Gly Arg Glu Gln Glu Met Leu
                 155                 160                 165

 His Lys His Ser Pro Pro Arg Gly Arg Pro Glu Met Ala Gly Ala
                 170                 175                 180

 Thr Gln Glu Ala Gln Gln Glu Gln Thr Arg Ser Lys Glu Lys Arg
                 185                 190                 195

 Leu Gln Ala Pro Val Gly Gln Arg Gly Ala Asp Gly Lys His Gly
                 200                 205                 210

 Val Leu Thr Trp Leu Arg Glu Asn Pro Gly Gly Ser Glu Glu Ser
                 215                 220                 225

 Leu Arg Lys Leu Pro Gly Pro Leu Pro Pro Ala Gly Ser Leu Gln
                 230                 235                 240

 Thr Ser Val Thr Pro Arg Pro Ser Trp Ala Glu Ala Pro Trp Leu
                 245                 250                 255

 Val Gly Gly Gln Pro Ala Leu Trp Ser Ile Leu Leu Met Pro Pro
                 260                 265                 270

 Arg Tyr Gly Ile Pro Phe Tyr His Ser Thr Pro Thr Thr Gly Ala
                 275                 280                 285

 Trp Gln Glu Val Trp Arg Glu Gln Arg Ile Pro Leu Ser Leu Asn
                 290                 295                 300

 Ala Pro Lys Gly Leu Trp Ser Gln Asn Gln Leu Ala Ser Ser Ser
                 305                 310                 315

 Pro Thr Pro Gly Ser Leu Pro Gln Gly Pro Ala Gln Leu Ser Pro
                 320                 325                 330

 Gly Glu Met Glu Glu Ser Asp Gln Gly His Thr Gly Ala Leu Ala
                 335                 340                 345

 Thr Cys Ala Gly His Glu Asp Lys Ala Gly Cys Pro Pro Arg Pro
                 350                 355                 360

 His Pro Pro Pro Ala Pro Pro Ala Arg Ser Arg Pro Tyr Ala Cys
                 365                 370                 375

 Ser Val Cys Gly Lys Arg Phe Ser Leu Lys His Gln Met Glu Thr
                 380                 385                 390

 His Tyr Arg Val His Thr Gly Glu Lys Pro Phe Ser Cys Ser Leu
                 395                 400                 405

 Cys Pro Gln Arg Ser Arg Asp Phe Ser Ala Met Thr Lys His Leu
                 410                 415                 420

 Arg Thr His Gly Ala Ala Pro Tyr Arg Cys Ser Leu Cys Gly Ala
                 425                 430                 435

 Gly Cys Pro Ser Leu Ala Ser Met Gln Ala His Met Arg Gly His
                 440                 445                 450

 Ser Pro Ser Gln Leu Pro Pro Gly Trp Thr Ile Arg Ser Thr Phe
                 455                 460                 465

 Leu Tyr Ser Ser Ser Arg Pro Ser Arg Pro Ser Thr Ser Pro Cys
                 470                 475                 480

 Cys Pro Ser Ser Ser Thr Thr
                 485

<210> 3513
<211> 2478
<212> DNA
<213> Homo sapien

<400> 3513
 tttgtgttcc ctcaaatggc ggtgtgaaga gagttcgcct gagccagatc 50

 ccaggtttca ctgaagaaac ttcttagagg ttcattgcac ttctgagatt 100

 taatgtttac aacttggagt tgtcgacctt cttataagat acattttgga 150

 agtcaaaatg aaagttttct gtgaagtttt agaagagtta tacaagaagg 200

 tacttcttgg agccacactt gaaaatgaca gccatgatta catcttttat 250

 ctcaacccag cagtttcaga tcaagattgt tctacagcca cctccttaga 300

 atgggcaaac acctgtggta tccagggcag gcatcagccc atctctgttg 350

 gtgtggctcc cattgctgta gcacctgtgt gtttgaagac caactctcag 400

 atgagcggtt ccagagaagt aatgctcctt cagttaacag tgatcaaagt 450

 gatgacaacc cggatattgt ctgtcaaaac cgagttccat gcaaaggagc 500

 agtacagaga tgtaattaaa attctcttag aatcagccaa agtcgattct 550

 aaattaatct gcatgttcca aaattcagat aaattgttat ctcacatggc 600

 tgcacagtgc cttgcattgc ttctatattt ccaattgaga gaaaagataa 650

 ccttaagtaa ttcctggatt gctttttgcc agaaaaatct ttctgaatac 700

 tctgagagta ataaagcaat atactgcctc tggactctta cagcaataat 750

 aaaagaaatc tttaaagatt catgttcaca gaaaacagaa attctaaagc 800

 agttcctgac tcatttcgac accatttttg aagtgtttta caattcctta 850

 ttctctcagc attttgaaaa ctgccgggat acttctaaaa tagtaaacat 900

 cctgatgtgt ttcctggatt tgcttgagct tctcatcgcc tccagaatcc 950

 acctgaagtt acatttcact tgccagagga ttttattttt gaaaccatct 1000

 tgcatgctag aagttattac ctggcctatt caggcttttg ttaaaaggaa 1050

 ggtcatcata ttcctcaaaa agtgccttct ctgtaaagtg ggtgaagacc 1100

 tctgtcgtgg atctgtgcct gccttaatgc cgccagacca tcatgtagcg 1150

 gtggacatgc tggctttagc taatgctgtt ttgcaagctg tgaattcggg 1200

 gttgttgaag acactgtctg tttatgaaaa acattccttt tttggaggtg 1250

 atgaagttca acctgaatgt gaacttatca ctagtccaga tcatgtgatc 1300

 cttagagcag caagcttagt tataatgaaa tccttagaaa tcaagtttca 1350

 aaattattct tcagcaagtg aaatgaaagg tgcgtgacca tggcccactg 1400

 cagccctgac cccccttcgg cccatgctat tcctcctgtc ccaacctggg 1450

 aggtcctggc ctgggagatc aaggctacag tgagccgcga cccatcgcac 1500

 acctgcactc cagtcctggt gcaacagatg gagatccttt cagggagaga 1550

 gagagagaga gaggagaaga cagagagatt aaagaaaaat atgttcactc 1600

 ccacttatgt gtttattgtt attattgttt gttgttattt ctttgttatt 1650

 gttgtgttta ctgtttattt attttgaggc agggtcttgc tctgtctccc 1700

 aggctcactg cagcctcaac gttttgagct gaagtgatcc tctcgcctct 1750

 gcttccccac cccatttgta ttaatccttc atacaattag tgtttctact 1800

 aatgtagatt attgaaaatt agatattgaa ttaaagctaa tatatgagaa 1850

 gttatattga caaagaaatt gttacatata taatttccag aatagtaact 1900

 caggagttca aagtcttcca ttttacttga gaaaaatgaa tagtaaatgt 1950

 ctctaaacag gcagcataca gattcagtga aaagtttgaa ttgtgagcaa 2000

 tgacatcact gaattgcttt ggatataatt tagcttttaa taactacaca 2050

 ttagttataa ttctgtgcag ttttaattta taacactaga tggcacctgt 2100

 tatataattc agttttaaat tgtagttcaa actacctaaa acgttttttt 2150

 atttttgtgc ttaataatag tacttctatg ctttaaacaa acaaaaaata 2200

 tgtttttctg ttattttgaa gacaaaatta tttttgcttg gttgcattct 2250

 tggacagaca gctctggcat ccgatgaagt gatcttagtt gtctgctcat 2300

 ttatttatct gcttttagca agaaatcaca taacttttat ttctaagaga 2350

 cagttgttag gcagttgttg caaatagatg atgtagctgt acattttaaa 2400

 tgtatgctct ggaatgagtc actttttttc cctgagcctc agtgtcctca 2450

 tttgccaaat aaagatgctt cctaactg 2478

<210> 3514
<211> 409
<212> PRT
<213> Homo sapien

<400> 3514
 Met Lys Val Phe Cys Glu Val Leu Glu Glu Leu Tyr Lys Lys Val
   1               5                  10                  15

 Leu Leu Gly Ala Thr Leu Glu Asn Asp Ser His Asp Tyr Ile Phe
                  20                  25                  30

 Tyr Leu Asn Pro Ala Val Ser Asp Gln Asp Cys Ser Thr Ala Thr
                  35                  40                  45

 Ser Leu Glu Trp Ala Asn Thr Cys Gly Ile Gln Gly Arg His Gln
                  50                  55                  60

 Pro Ile Ser Val Gly Val Ala Pro Ile Ala Val Ala Pro Val Cys
                  65                  70                  75

 Leu Lys Thr Asn Ser Gln Met Ser Gly Ser Arg Glu Val Met Leu
                  80                  85                  90

 Leu Gln Leu Thr Val Ile Lys Val Met Thr Thr Arg Ile Leu Ser
                  95                 100                 105

 Val Lys Thr Glu Phe His Ala Lys Glu Gln Tyr Arg Asp Val Ile
                 110                 115                 120

 Lys Ile Leu Leu Glu Ser Ala Lys Val Asp Ser Lys Leu Ile Cys
                 125                 130                 135

 Met Phe Gln Asn Ser Asp Lys Leu Leu Ser His Met Ala Ala Gln
                 140                 145                 150

 Cys Leu Ala Leu Leu Leu Tyr Phe Gln Leu Arg Glu Lys Ile Thr
                 155                 160                 165

 Leu Ser Asn Ser Trp Ile Ala Phe Cys Gln Lys Asn Leu Ser Glu
                 170                 175                 180

 Tyr Ser Glu Ser Asn Lys Ala Ile Tyr Cys Leu Trp Thr Leu Thr
                 185                 190                 195

 Ala Ile Ile Lys Glu Ile Phe Lys Asp Ser Cys Ser Gln Lys Thr
                 200                 205                 210

 Glu Ile Leu Lys Gln Phe Leu Thr His Phe Asp Thr Ile Phe Glu
                 215                 220                 225

 Val Phe Tyr Asn Ser Leu Phe Ser Gln His Phe Glu Asn Cys Arg
                 230                 235                 240

 Asp Thr Ser Lys Ile Val Asn Ile Leu Met Cys Phe Leu Asp Leu
                 245                 250                 255

 Leu Glu Leu Leu Ile Ala Ser Arg Ile His Leu Lys Leu His Phe
                 260                 265                 270

 Thr Cys Gln Arg Ile Leu Phe Leu Lys Pro Ser Cys Met Leu Glu
                 275                 280                 285

 Val Ile Thr Trp Pro Ile Gln Ala Phe Val Lys Arg Lys Val Ile
                 290                 295                 300

 Ile Phe Leu Lys Lys Cys Leu Leu Cys Lys Val Gly Glu Asp Leu
                 305                 310                 315

 Cys Arg Gly Ser Val Pro Ala Leu Met Pro Pro Asp His His Val
                 320                 325                 330

 Ala Val Asp Met Leu Ala Leu Ala Asn Ala Val Leu Gln Ala Val
                 335                 340                 345

 Asn Ser Gly Leu Leu Lys Thr Leu Ser Val Tyr Glu Lys His Ser
                 350                 355                 360

 Phe Phe Gly Gly Asp Glu Val Gln Pro Glu Cys Glu Leu Ile Thr
                 365                 370                 375

 Ser Pro Asp His Val Ile Leu Arg Ala Ala Ser Leu Val Ile Met
                 380                 385                 390

 Lys Ser Leu Glu Ile Lys Phe Gln Asn Tyr Ser Ser Ala Ser Glu
                 395                 400                 405

 Met Lys Gly Ala


<210> 3515
<211> 850
<212> DNA
<213> Homo sapien

<400> 3515
 gaattccggc aaaatgcatg acagtaacaa tgtggagaaa gacattacac 50

 catctgaatt gcctgcaaac ccaggttgtc tgcattcaaa agagcattct 100

 attaaagcta ccttaatttg gcgcttattt ttcttaatca tgtttctgac 150

 aatcatagtg tgtggaatgg ttgctgcttt aagcgcaata agagctaact 200

 gccatcaaga gccatcagta tgtcttcaag ctgcatgccc agaaagctgg 250

 attggttttc aaagaaagtg tttctatttt tctgatgaca ccaagaactg 300

 gacatcaagt cagaggtttt gtgactcaca agatgctgat cttgctcagg 350

 ttgaaagctt ccaggaactg aatttcctgt tgagatataa aggcccatct 400

 gatcactgga ttgggctgag cagagaacaa ggccaaccat ggaaatggat 450

 aaatggtact gaatggacaa gacagtttcc tatcctggga gcaggagagt 500

 gtgcctattt gaatgacaaa ggtgccagta gtgccaggca ctacacagag 550

 aggaagtgga tttgttccaa atcagatata catgtctaga tgttacagca 600

 aagccccaac taatctttag aagcatattg gaactgataa ctccatttta 650

 aaatgagcaa agaatttatt tcttatacca acaggtatat gaaaatatgc 700

 tcaatatcac taataactgg gaaaatacaa atcaaaatca tagtaaaata 750

 ttacctgttt tcatggtgct aatattacct gttctcccac tgctaatgac 800

 atacccgaga atgagtaatt tataaataaa agagatttaa ttgaaaaaaa 850

<210> 3516
<211> 191
<212> PRT
<213> Homo sapien

<400> 3516
 Met His Asp Ser Asn Asn Val Glu Lys Asp Ile Thr Pro Ser Glu
   1               5                  10                  15

 Leu Pro Ala Asn Pro Gly Cys Leu His Ser Lys Glu His Ser Ile
                  20                  25                  30

 Lys Ala Thr Leu Ile Trp Arg Leu Phe Phe Leu Ile Met Phe Leu
                  35                  40                  45

 Thr Ile Ile Val Cys Gly Met Val Ala Ala Leu Ser Ala Ile Arg
                  50                  55                  60

 Ala Asn Cys His Gln Glu Pro Ser Val Cys Leu Gln Ala Ala Cys
                  65                  70                  75

 Pro Glu Ser Trp Ile Gly Phe Gln Arg Lys Cys Phe Tyr Phe Ser
                  80                  85                  90

 Asp Asp Thr Lys Asn Trp Thr Ser Ser Gln Arg Phe Cys Asp Ser
                  95                 100                 105

 Gln Asp Ala Asp Leu Ala Gln Val Glu Ser Phe Gln Glu Leu Asn
                 110                 115                 120

 Phe Leu Leu Arg Tyr Lys Gly Pro Ser Asp His Trp Ile Gly Leu
                 125                 130                 135

 Ser Arg Glu Gln Gly Gln Pro Trp Lys Trp Ile Asn Gly Thr Glu
                 140                 145                 150

 Trp Thr Arg Gln Phe Pro Ile Leu Gly Ala Gly Glu Cys Ala Tyr
                 155                 160                 165

 Leu Asn Asp Lys Gly Ala Ser Ser Ala Arg His Tyr Thr Glu Arg
                 170                 175                 180

 Lys Trp Ile Cys Ser Lys Ser Asp Ile His Val
                 185                 190

<210> 3517
<211> 2970
<212> DNA
<213> Homo sapien

<400> 3517
 tgggatatgg gatattgtaa tgggagagca ggaaatttaa ggtcggaggt 50

 atttgtttag gatacctcag tattctagag ctatgggatt tattttgctt 100

 tgaagtccag aggtatttag ctttattcta aaagcgatga agttcctctt 150

 aattaaagac gctcctggaa aaaaaaaaag gaaaaattta atgctgtctt 200

 ttaaaaggaa acatgccaaa ggccaggatt tgtttgatca gattgtgtac 250

 cacttggacc ttgtggaaac agattacttt ggcctccagt tcctcgactc 300

 tgcccaggtt gcgcactggc tggatcatgc caaacccata aaaaagcaga 350

 tgaaaattgg acctgcttat gctttacact ttcgagttaa atactattct 400

 tcagaaccaa acaaccttcg tgaggagttt acaaggtacc tgtttgtttt 450

 acaactcagg catgacattc tttctggaaa attgaaatgc ccttatgaaa 500

 cagctgtgga attagctgct ctctgtctac aagcggagct tggggagtgc 550

 gagcttccag aacacacacc agagcttgtg tctgagtttc ggttcattcc 600

 aaatcagaca gaagcaatgg aatttgatat cttccagaga tggaaagagt 650

 gcaggggaaa gagccctgcc caggcggaac tctcctatct gaataaagcg 700

 aagtggctgg aaatgtatgg ggtagacatg cacgttgtca ggggaagaga 750

 tggctgtgaa tattctcttg gactgacccc gacaggcata ttaatctttg 800

 aaggagctaa caaaataggc ttattctttt ggcctaaaat taccaaaatg 850

 gattttaaaa agagcaaatt gacactcgtg gtggtcgagg atgatgatca 900

 gggacgtgag caagagcaca cgtttgtgtt ccggttagac agtgccagga 950

 cctgcaaaca cctttggaag tgtgcagttg agcaccacgc attcttccga 1000

 ctgcggacgc caggaaacag caaatccaat agatccgact ttatcaggct 1050

 gggctctcgc ttcagattta gtgggcggac agaatatcaa gctacacatg 1100

 gctccaggtt acgaagaacc agcacctttg agaggaagcc tagtaaacgt 1150

 tatccatccc ggagacattc aacgttcaaa gcaagcaacc cagtgatagc 1200

 agcccagctc tgctctaaaa caaatccaga agtccataat taccagcctc 1250

 aatatcatcc taatatccat cccagccagc cccggtggca tcctcactct 1300

 ccaaatgtca ggccatcctt tcaggatgac aggtcgcatt ggaaagcatc 1350

 ggccagtgga gatgacagcc attttgatta tgtccacgac cagaaccaga 1400

 agaacttagg agggatgcaa agtatgatgt atcgagataa actcatgact 1450

 gcactttgag agactgaagc atctctcttc cattcacctt catagtttca 1500

 ttgcattcca tgaaaagtgt cttggcctca gatggatgga tgtgtttgga 1550

 cgagtgtctt taaggagtag tcctgaaagg tgtttttggt gtccatgtaa 1600

 atatttgaag ataaaaccac tatagcttgt cataatttac tgttgactgc 1650

 attctcatta aaatgaaggt aaaggctcag gaatcatatt gatgttctga 1700

 ttttaaaatt ggagtcaaag tctatgttta tcattttact atgttcctga 1750

 tgttctttgt tatttaatta atgggagcaa ataaaaccag aagagcttgg 1800

 gaagattgct cagcatatat tcctgtcgta gaagttgaga ttgctagggt 1850

 ccagtttccc tagtgtggcc tggacgagtc atttcccctt cattgacctc 1900

 attttcccca tctgaaaaga gagggttgga ctaagtgatc tccaaggtcc 1950

 tttccaactc taaaattctg caatttgtta acatttcatt ttgtttaggt 2000

 tgaggacata cattcaaact aattttatca caaggaaaac tgcaataccc 2050

 acttccttga cagagttact cctttcagaa gctaaataaa gtatataact 2100

 tattagatgt tatatagata cagggggact ttgaatttca catcttaaag 2150

 cagttgagct actttgaatt taagcagtcg tactaatctt aaattgcata 2200

 gcatttgttt tgatcgaatt tgctgctcaa gtatgggaat aatttttaat 2250

 gtcttaatga ttggtgctgc taacttgcgt gatttcagaa gacataattg 2300

 tgaatacaca ctgtcagaat tgggggattg gtttttaccc tagacttcac 2350

 tcttaaaaag caacgtgcaa tcaagatcat ttatggctca aatgaaagca 2400

 tataaggttt tcttgaagtt gtgccaaagc attctgtaga gtaggatgag 2450

 atggttgttg ccctagtctg ttggtagaac cagaaatcaa tatgttgtct 2500

 tttaggttaa agcttgtacc aaaatattta tttcccccat ttcaagccct 2550

 gagtcaaaca tttttttctc ttaataatag acctgaaatg ttttattagt 2600

 atttctgtga aatcagttga ttcttgtgcc atttttgtat atgtaattgt 2650

 aattttgccc atgttaggcc ctctaaaaaa tgtttgacat cctttgagat 2700

 attttattac taaaatctga tcttttttgg ctactgcaaa aatctattca 2750

 gcaagaaggt atcagctgca taccttgcac agtggagctg actacctata 2800

 aactctccct aaggcatttg tttacaggtg tattccattt tagcagacgt 2850

 tctgatgctc agtgtatgtg ctgcatacaa ataaatgtgt tctgaatctt 2900

 ttcatcttat tgatagcatt tttacaaatg tgtttccaag gaataaagat 2950

 tattcttgct ttaaaaaaaa 2970

<210> 3518
<211> 440
<212> PRT
<213> Homo sapien

<400> 3518
 Met Lys Phe Leu Leu Ile Lys Asp Ala Pro Gly Lys Lys Lys Arg
   1               5                  10                  15

 Lys Asn Leu Met Leu Ser Phe Lys Arg Lys His Ala Lys Gly Gln
                  20                  25                  30

 Asp Leu Phe Asp Gln Ile Val Tyr His Leu Asp Leu Val Glu Thr
                  35                  40                  45

 Asp Tyr Phe Gly Leu Gln Phe Leu Asp Ser Ala Gln Val Ala His
                  50                  55                  60

 Trp Leu Asp His Ala Lys Pro Ile Lys Lys Gln Met Lys Ile Gly
                  65                  70                  75

 Pro Ala Tyr Ala Leu His Phe Arg Val Lys Tyr Tyr Ser Ser Glu
                  80                  85                  90

 Pro Asn Asn Leu Arg Glu Glu Phe Thr Arg Tyr Leu Phe Val Leu
                  95                 100                 105

 Gln Leu Arg His Asp Ile Leu Ser Gly Lys Leu Lys Cys Pro Tyr
                 110                 115                 120

 Glu Thr Ala Val Glu Leu Ala Ala Leu Cys Leu Gln Ala Glu Leu
                 125                 130                 135

 Gly Glu Cys Glu Leu Pro Glu His Thr Pro Glu Leu Val Ser Glu
                 140                 145                 150

 Phe Arg Phe Ile Pro Asn Gln Thr Glu Ala Met Glu Phe Asp Ile
                 155                 160                 165

 Phe Gln Arg Trp Lys Glu Cys Arg Gly Lys Ser Pro Ala Gln Ala
                 170                 175                 180

 Glu Leu Ser Tyr Leu Asn Lys Ala Lys Trp Leu Glu Met Tyr Gly
                 185                 190                 195

 Val Asp Met His Val Val Arg Gly Arg Asp Gly Cys Glu Tyr Ser
                 200                 205                 210

 Leu Gly Leu Thr Pro Thr Gly Ile Leu Ile Phe Glu Gly Ala Asn
                 215                 220                 225

 Lys Ile Gly Leu Phe Phe Trp Pro Lys Ile Thr Lys Met Asp Phe
                 230                 235                 240

 Lys Lys Ser Lys Leu Thr Leu Val Val Val Glu Asp Asp Asp Gln
                 245                 250                 255

 Gly Arg Glu Gln Glu His Thr Phe Val Phe Arg Leu Asp Ser Ala
                 260                 265                 270

 Arg Thr Cys Lys His Leu Trp Lys Cys Ala Val Glu His His Ala
                 275                 280                 285

 Phe Phe Arg Leu Arg Thr Pro Gly Asn Ser Lys Ser Asn Arg Ser
                 290                 295                 300

 Asp Phe Ile Arg Leu Gly Ser Arg Phe Arg Phe Ser Gly Arg Thr
                 305                 310                 315

 Glu Tyr Gln Ala Thr His Gly Ser Arg Leu Arg Arg Thr Ser Thr
                 320                 325                 330

 Phe Glu Arg Lys Pro Ser Lys Arg Tyr Pro Ser Arg Arg His Ser
                 335                 340                 345

 Thr Phe Lys Ala Ser Asn Pro Val Ile Ala Ala Gln Leu Cys Ser
                 350                 355                 360

 Lys Thr Asn Pro Glu Val His Asn Tyr Gln Pro Gln Tyr His Pro
                 365                 370                 375

 Asn Ile His Pro Ser Gln Pro Arg Trp His Pro His Ser Pro Asn
                 380                 385                 390

 Val Arg Pro Ser Phe Gln Asp Asp Arg Ser His Trp Lys Ala Ser
                 395                 400                 405

 Ala Ser Gly Asp Asp Ser His Phe Asp Tyr Val His Asp Gln Asn
                 410                 415                 420

 Gln Lys Asn Leu Gly Gly Met Gln Ser Met Met Tyr Arg Asp Lys
                 425                 430                 435

 Leu Met Thr Ala Leu
                 440

<210> 3519
<211> 2468
<212> DNA
<213> Homo sapien

<400> 3519
 accgggcacc ggacggctcg ggtactttcg ttcttaatta ggtcatgccc 50

 gtgtgagcca ggaaagggct gtgtttatgg gaagccagta acactgtggc 100

 ctactatctc ttccgtggtg ccatctacat ttttgggact cgggaattat 150

 gaggtagagg tggaggcgga gccggatgtc agaggtcctg aaatagtcac 200

 catgggggaa aatgatccgc ctgctgttga agcccccttc tcattccgat 250

 cgctttttgg ccttgatgat ttgaaaataa gtcctgttgc accagatgca 300

 gatgctgttg ctgcacagat cctgtcactg ctgccattga agttttttcc 350

 aatcatcgtc attgggatca ttgcattgat attagcactg gccattggtc 400

 tgggcatcca cttcgactgc tcagggaagt acagatgtcg ctcatccttt 450

 aagtgtatcg agctgatagc tcgatgtgac ggagtctcgg attgcaaaga 500

 cggggaggac gagtaccgct gtgtccgggt gggtggtcag aatgccgtgc 550

 tccaggtgtt cacagctgct tcgtggaaga ccatgtgctc cgatgactgg 600

 aagggtcact acgcaaatgt tgcctgtgcc caactgggtt tcccaagcta 650

 tgtgagttca gataacctca gagtgagctc gctggagggg cagttccggg 700

 aggagtttgt gtccatcgat cacctcttgc cagatgacaa ggtgactgca 750

 ttacaccact cagtatatgt gagggaggga tgtgcctctg gccacgtggt 800

 taccttgcag tgcacagcct gtggtcatag aaggggctac agctcacgca 850

 tcgtgggtgg aaacatgtcc ttgctctcgc agtggccctg gcaggccagc 900

 cttcagttcc agggctacca cctgtgcggg ggctctgtca tcacgcccct 950

 gtggatcatc actgctgcac actgtgttta tgacttgtac ctccccaagt 1000

 catggaccat ccaggtgggt ctagtttccc tgttggacaa tccagcccca 1050

 tcccacttgg tggagaagat tgtctaccac agcaagtaca agccaaagag 1100

 gctgggcaat gacatcgccc ttatgaagct ggccgggcca ctcacgttca 1150

 atgaaatgat ccagcctgtg tgcctgccca actctgaaga gaacttcccc 1200

 gatggaaaag tgtgctggac gtcaggatgg ggggccacag aggatggagc 1250

 aggtgacgcc tcccctgtcc tgaaccacgc ggccgtccct ttgatttcca 1300

 acaagatctg caaccacagg gacgtgtacg gtggcatcat ctccccctcc 1350

 atgctctgcg cgggctacct gacgggtggc gtggacagct gccaggggga 1400

 cagcgggggg cccctggtgt gtcaagagag gaggctgtgg aagttagtgg 1450

 gagcgaccag ctttggcatc ggctgcgcag aggtgaacaa gcctggggtg 1500

 tacacccgtg tcacctcctt cctggactgg atccacgagc agatggagag 1550

 agacctaaaa acctgaagag gaaggggaca agtagccacc tgagttcctg 1600

 aggtgatgaa gacagcccga tcctcccctg gactcccgtg taggaacctg 1650

 cacacgagca gacacccttg gagctctgag ttccggcacc agtagcaggc 1700

 ccgaaagagg cacccttcca tctgattcca gcacaacctt caagctgctt 1750

 tttgtttttt gtttttttga ggtggagtct cgctctgttg cccaggctgg 1800

 agtgcagtgg cgaaatccct gctcactgca gcctccgctt ccctggttca 1850

 agcgattctc ttgcctcagc ttccccagta gctgggacca caggtgcccg 1900

 ccaccacacc caactaattt ttgtattttt agtagagaca gggtttcacc 1950

 atgttggcca ggctgctctc aaacccctga cctcaaatga tgtgcctgct 2000

 tcagcctccc acagtgctgg gattacaggc atgggccacc acgcctagcc 2050

 tcacgctcct ttctgatctt cactaagaac aaaagaagca gcaacttgca 2100

 agggcggcct ttcccactgg tccatctggt tttctctcca ggggtcttgc 2150

 aaaattcctg acgagataag cagttatgtg acctcacgtg caaagccacc 2200

 aacagccact cagaaaagac gcaccagccc agaagtgcag aactgcagtc 2250

 actgcacgtt ttcatctcta gggaccagaa ccaaacccac cctttctact 2300

 tccaagactt attttcacat gtggggaggt taatctagga atgactcgtt 2350

 taaggcctat tttcatgatt tctttgtagc atttggtgct tgacgtatta 2400

 ttgtcctttg attccaaata atatgtttcc ttccctcaaa aaaaaaaaaa 2450

 aaaaaaaaaa aaaaaaaa 2468

<210> 3520
<211> 454
<212> PRT
<213> Homo sapien

<400> 3520
 Met Gly Glu Asn Asp Pro Pro Ala Val Glu Ala Pro Phe Ser Phe
   1               5                  10                  15

 Arg Ser Leu Phe Gly Leu Asp Asp Leu Lys Ile Ser Pro Val Ala
                  20                  25                  30

 Pro Asp Ala Asp Ala Val Ala Ala Gln Ile Leu Ser Leu Leu Pro
                  35                  40                  45

 Leu Lys Phe Phe Pro Ile Ile Val Ile Gly Ile Ile Ala Leu Ile
                  50                  55                  60

 Leu Ala Leu Ala Ile Gly Leu Gly Ile His Phe Asp Cys Ser Gly
                  65                  70                  75

 Lys Tyr Arg Cys Arg Ser Ser Phe Lys Cys Ile Glu Leu Ile Ala
                  80                  85                  90

 Arg Cys Asp Gly Val Ser Asp Cys Lys Asp Gly Glu Asp Glu Tyr
                  95                 100                 105

 Arg Cys Val Arg Val Gly Gly Gln Asn Ala Val Leu Gln Val Phe
                 110                 115                 120

 Thr Ala Ala Ser Trp Lys Thr Met Cys Ser Asp Asp Trp Lys Gly
                 125                 130                 135

 His Tyr Ala Asn Val Ala Cys Ala Gln Leu Gly Phe Pro Ser Tyr
                 140                 145                 150

 Val Ser Ser Asp Asn Leu Arg Val Ser Ser Leu Glu Gly Gln Phe
                 155                 160                 165

 Arg Glu Glu Phe Val Ser Ile Asp His Leu Leu Pro Asp Asp Lys
                 170                 175                 180

 Val Thr Ala Leu His His Ser Val Tyr Val Arg Glu Gly Cys Ala
                 185                 190                 195

 Ser Gly His Val Val Thr Leu Gln Cys Thr Ala Cys Gly His Arg
                 200                 205                 210

 Arg Gly Tyr Ser Ser Arg Ile Val Gly Gly Asn Met Ser Leu Leu
                 215                 220                 225

 Ser Gln Trp Pro Trp Gln Ala Ser Leu Gln Phe Gln Gly Tyr His
                 230                 235                 240

 Leu Cys Gly Gly Ser Val Ile Thr Pro Leu Trp Ile Ile Thr Ala
                 245                 250                 255

 Ala His Cys Val Tyr Asp Leu Tyr Leu Pro Lys Ser Trp Thr Ile
                 260                 265                 270

 Gln Val Gly Leu Val Ser Leu Leu Asp Asn Pro Ala Pro Ser His
                 275                 280                 285

 Leu Val Glu Lys Ile Val Tyr His Ser Lys Tyr Lys Pro Lys Arg
                 290                 295                 300

 Leu Gly Asn Asp Ile Ala Leu Met Lys Leu Ala Gly Pro Leu Thr
                 305                 310                 315

 Phe Asn Glu Met Ile Gln Pro Val Cys Leu Pro Asn Ser Glu Glu
                 320                 325                 330

 Asn Phe Pro Asp Gly Lys Val Cys Trp Thr Ser Gly Trp Gly Ala
                 335                 340                 345

 Thr Glu Asp Gly Ala Gly Asp Ala Ser Pro Val Leu Asn His Ala
                 350                 355                 360

 Ala Val Pro Leu Ile Ser Asn Lys Ile Cys Asn His Arg Asp Val
                 365                 370                 375

 Tyr Gly Gly Ile Ile Ser Pro Ser Met Leu Cys Ala Gly Tyr Leu
                 380                 385                 390

 Thr Gly Gly Val Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro Leu
                 395                 400                 405

 Val Cys Gln Glu Arg Arg Leu Trp Lys Leu Val Gly Ala Thr Ser
                 410                 415                 420

 Phe Gly Ile Gly Cys Ala Glu Val Asn Lys Pro Gly Val Tyr Thr
                 425                 430                 435

 Arg Val Thr Ser Phe Leu Asp Trp Ile His Glu Gln Met Glu Arg
                 440                 445                 450

 Asp Leu Lys Thr


<210> 3521
<211> 2115
<212> DNA
<213> Homo sapien

<400> 3521
 tccaaagaat gttgctacag agacacaatt gaaaggtggt cagcattctc 50

 aagctgctcc agtgaaatgg attttccaag ataatctaca gccttttacg 100

 ccatctcttg ttcctgttaa gtcttcaaat aatgtggctt caaagatttt 150

 aaaaactttt gtagatagga aaaatttggg agataatact ataaatatgc 200

 caccattgag taccatcgat cctagtggga cgcgatccaa aaatatgcct 250

 attaaagata atgctttggt tatgtttaat gggaaagtct atctgttggc 300

 taaaaagggg acagatgttc tgccatcaca aattgaccaa cagaattctg 350

 tttctcctga tactccagta agaaaagaca cgttacagac agtgagttca 400

 agtccagtca cagaaatatc cagagaggtt gtaaatattg ttttggctaa 450

 aagtaaatct tcccagatgg agacaaaatc actttccaat acccagcttg 500

 cttccatggc caatctaagg gcagagaaga ataaagtgga gaaaccatct 550

 ccttctacca caaatccaca tatgaaccaa tccagtaact acttaaaaca 600

 gagtaagact ttattcacaa atccaatctt tccagttgga tttagtacag 650

 gacacaatgc ccccagaaaa gtaacagccg tcatttatgc tagaaaagga 700

 agtgtcctcc agagcataga gaaaataagt tcctctgttg atgcaacaac 750

 tgttacttca caacagtgtg ttttcagaga ccaagaacca aagatccata 800

 atgagatggc atcaacatca gataaaggtg cccaaggaag aaatgacaag 850

 aaagattctc aaggaagaag taataaggca ttacatctga agagtgatgc 900

 tgaatttaaa aagatatttg gccttactaa ggatttgaga gtgtgcctta 950

 ctcgaattcc tgaccatttg acctctggag aaggtttcga ttcctttagc 1000

 agtttggtaa agagtggtac ttacaaagag acagagttta tggtgaagga 1050

 aggagagaga aaacagcaga attttgataa gaaaagaaaa gcaaaaacta 1100

 ataagaagat ggatcacata aagaagagaa aaacagagaa tgcttataac 1150

 gcaatcataa atggggaagc taatgtcacc ggttcccaac tccagtattt 1200

 taccaacttc agatgtgtca caacataaca ttctcacgag tcacagcaaa 1250

 accagacaag aaaagagaac tgagatggaa tactataccc atgagaagca 1300

 agagaaaggc actttgaatt caaatgcagc ttatgaacaa agtcatttct 1350

 tcaataaaaa ttataccgaa gatattttcc cagtgacacc accggagtta 1400

 gaagaaacca ttcgagatga aaaaataaga agacttaagc aggtgctgag 1450

 agagaaagaa gcagctcttg aagaaatgcg taagaagatg caccaaaaat 1500

 aaaatctcct gtaaagactt cagtgaaata gctgtttttt aaaatatact 1550

 tcagcattaa taagttaatt gtaggtgtgt tctgaaagtg tctttgaata 1600

 tgaagcttgt tttttcatca gtcgattgta caactttaag gaatacagaa 1650

 aaggttgatt cacatatgac ttgtgaataa tttacatggg gtatctatac 1700

 ctttgtctta gatacctttt tttggaagga taaattttat atttttctat 1750

 tattttaact agaattctcc aagtttgaat atttgggcag ggtttttgtt 1800

 attgtttgta tctttaccta aattgctcag gcattattcc agcagtagat 1850

 agtgactgtg tattactgaa attttacaat tcaagagagg aaatcagctc 1900

 caaacttagc ttttccagtg gatttgtata tgtacttgct ttatctcttt 1950

 acccttaaaa tgatgatacc ttgtattcac cattgttttt tttaatgtcg 2000

 tgaaataata tgtattatgg caacattatt taaacattca aacatttctc 2050

 aagaatgagc aacatttgta actttacaat gtaattttat ataatccaaa 2100

 ggtattttag aattc 2115

<210> 3522
<211> 343
<212> PRT
<213> Homo sapien

<400> 3522
 Met Pro Pro Leu Ser Thr Ile Asp Pro Ser Gly Thr Arg Ser Lys
   1               5                  10                  15

 Asn Met Pro Ile Lys Asp Asn Ala Leu Val Met Phe Asn Gly Lys
                  20                  25                  30

 Val Tyr Leu Leu Ala Lys Lys Gly Thr Asp Val Leu Pro Ser Gln
                  35                  40                  45

 Ile Asp Gln Gln Asn Ser Val Ser Pro Asp Thr Pro Val Arg Lys
                  50                  55                  60

 Asp Thr Leu Gln Thr Val Ser Ser Ser Pro Val Thr Glu Ile Ser
                  65                  70                  75

 Arg Glu Val Val Asn Ile Val Leu Ala Lys Ser Lys Ser Ser Gln
                  80                  85                  90

 Met Glu Thr Lys Ser Leu Ser Asn Thr Gln Leu Ala Ser Met Ala
                  95                 100                 105

 Asn Leu Arg Ala Glu Lys Asn Lys Val Glu Lys Pro Ser Pro Ser
                 110                 115                 120

 Thr Thr Asn Pro His Met Asn Gln Ser Ser Asn Tyr Leu Lys Gln
                 125                 130                 135

 Ser Lys Thr Leu Phe Thr Asn Pro Ile Phe Pro Val Gly Phe Ser
                 140                 145                 150

 Thr Gly His Asn Ala Pro Arg Lys Val Thr Ala Val Ile Tyr Ala
                 155                 160                 165

 Arg Lys Gly Ser Val Leu Gln Ser Ile Glu Lys Ile Ser Ser Ser
                 170                 175                 180

 Val Asp Ala Thr Thr Val Thr Ser Gln Gln Cys Val Phe Arg Asp
                 185                 190                 195

 Gln Glu Pro Lys Ile His Asn Glu Met Ala Ser Thr Ser Asp Lys
                 200                 205                 210

 Gly Ala Gln Gly Arg Asn Asp Lys Lys Asp Ser Gln Gly Arg Ser
                 215                 220                 225

 Asn Lys Ala Leu His Leu Lys Ser Asp Ala Glu Phe Lys Lys Ile
                 230                 235                 240

 Phe Gly Leu Thr Lys Asp Leu Arg Val Cys Leu Thr Arg Ile Pro
                 245                 250                 255

 Asp His Leu Thr Ser Gly Glu Gly Phe Asp Ser Phe Ser Ser Leu
                 260                 265                 270

 Val Lys Ser Gly Thr Tyr Lys Glu Thr Glu Phe Met Val Lys Glu
                 275                 280                 285

 Gly Glu Arg Lys Gln Gln Asn Phe Asp Lys Lys Arg Lys Ala Lys
                 290                 295                 300

 Thr Asn Lys Lys Met Asp His Ile Lys Lys Arg Lys Thr Glu Asn
                 305                 310                 315

 Ala Tyr Asn Ala Ile Ile Asn Gly Glu Ala Asn Val Thr Gly Ser
                 320                 325                 330

 Gln Leu Gln Tyr Phe Thr Asn Phe Arg Cys Val Thr Thr
                 335                 340

<210> 3523
<211> 1673
<212> DNA
<213> Homo sapien

<400> 3523
 ctctcctcgc ccgctgggtg ctgaagttgg gcggatggca gcaaaccggc 50

 tccgctagag gaccgagccg cccagccccg ctcccccgga cccatcggcg 100

 cgctgcccac acctccaggc gaccggccaa ctgggtcctg aagtagctga 150

 aatgcgaaaa aggcagcagt cccaaaatga aggaacacct gccgtgtctc 200

 aagctcctgg aaaccagagg cccaacaaca cctgttgctt ttgttggtgc 250

 tgttgttgca gctgctcctg cctcactgtg aggaatgaag aaagagggga 300

 aaatgcggga agacccacac acactacaaa aatggagagt atccaggtcc 350

 tagaggaatg ccaaaacccc actgcagagg aagtcttgtc ctggtctcaa 400

 aattttgaca agatgatgaa ggccccagca ggaagaaacc ttttcagaga 450

 gttcctccga acagaataca gtgaagagaa cctacttttc tggcttgctt 500

 gtgaagactt aaagaaggag cagaacaaaa aagtaattga agaaaaggct 550

 aggatgatat atgaagatta catttctata ctatcaccaa aagaggtcag 600

 tcttgattct cgagttagag aggtgatcaa tagaaatctg ttggatccca 650

 atcctcacat gtatgaagat gcccaacttc agatatatac tttaatgcac 700

 agagattctt ttccaaggtt tttgaactct caaatttata agtcatttgt 750

 tgaaagtact gctggctctt cttctgaatc ttaatgttca tttaaaaaca 800

 atcattttgg agggctgaga tgggaaataa aagtagttaa ataacatcag 850

 aaactgagtt cctggagaac tacagtttag cattcctcag gctactgtga 900

 aaacacaacc gttatggtct ttgtctccat ttttatcaag gttttccatg 950

 gttaagtttg gagaaaatac cacacaaaac aatgaattgc caaattgttt 1000

 gttttattca agactcattc tacttgcaag caaagtgtat ttgtagtcct 1050

 atgaacagtc tcctcgtgta tctccagaga ctgcatgtgc aaagtaaaat 1100

 gcttcatttg ccacatagtt gttgtaatat ttaatccagt agcataactt 1150

 atatctgtat ttaaggactt ttgtgcaata tggtcttaag aaataattgc 1200

 caaaaaaatc ggccatggtt ctgcattttt aacataatct aagacagaaa 1250

 aaaagcaatt tttactatgt aacaatggta ttcaacattc tatatactgt 1300

 gtttagtaca ctaattttga agccaatatt tctgtacatg aaaaagagct 1350

 atttatctct gtttgttgga aaatcctaat ggggattcct ctggttgttc 1400

 actgccaaaa ctgtggcatt ttcattacag gagagtttac tatgctaaaa 1450

 gcaaaaaaca aaaaaaaaaa aaaagggaag aaggaaaaaa gcaaaaaaca 1500

 atttgaagat atcctatctc aatgacaaat caaaagagtg atattgcttt 1550

 taactgtaat agaagaaaat gaatttatgt atatatcaga tgtccaatac 1600

 tgtaattaat ttattaaaga ctggctctcc agttttaaaa aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaaa aaa 1673

<210> 3524
<211> 210
<212> PRT
<213> Homo sapien

<400> 3524
 Met Arg Lys Arg Gln Gln Ser Gln Asn Glu Gly Thr Pro Ala Val
   1               5                  10                  15

 Ser Gln Ala Pro Gly Asn Gln Arg Pro Asn Asn Thr Cys Cys Phe
                  20                  25                  30

 Cys Trp Cys Cys Cys Cys Ser Cys Ser Cys Leu Thr Val Arg Asn
                  35                  40                  45

 Glu Glu Arg Gly Glu Asn Ala Gly Arg Pro Thr His Thr Thr Lys
                  50                  55                  60

 Met Glu Ser Ile Gln Val Leu Glu Glu Cys Gln Asn Pro Thr Ala
                  65                  70                  75

 Glu Glu Val Leu Ser Trp Ser Gln Asn Phe Asp Lys Met Met Lys
                  80                  85                  90

 Ala Pro Ala Gly Arg Asn Leu Phe Arg Glu Phe Leu Arg Thr Glu
                  95                 100                 105

 Tyr Ser Glu Glu Asn Leu Leu Phe Trp Leu Ala Cys Glu Asp Leu
                 110                 115                 120

 Lys Lys Glu Gln Asn Lys Lys Val Ile Glu Glu Lys Ala Arg Met
                 125                 130                 135

 Ile Tyr Glu Asp Tyr Ile Ser Ile Leu Ser Pro Lys Glu Val Ser
                 140                 145                 150

 Leu Asp Ser Arg Val Arg Glu Val Ile Asn Arg Asn Leu Leu Asp
                 155                 160                 165

 Pro Asn Pro His Met Tyr Glu Asp Ala Gln Leu Gln Ile Tyr Thr
                 170                 175                 180

 Leu Met His Arg Asp Ser Phe Pro Arg Phe Leu Asn Ser Gln Ile
                 185                 190                 195

 Tyr Lys Ser Phe Val Glu Ser Thr Ala Gly Ser Ser Ser Glu Ser
                 200                 205                 210

<210> 3525
<211> 980
<212> DNA
<213> Homo sapien

<400> 3525
 ggggcagacg tgggacggga aggacggctg ccgggactgg cgcgcgggga 50

 cactgggccg acgcgtggag tagcggggag agcgggaagc ctgagggggc 100

 ggggccggcg cgaggccgtg ggtgcggcac gaggatgccg gcggcgggac 150

 agcgcccgta ggcagcccca cgggcagggc gcgcgggcgg ggcggggcgg 200

 gccgggccag aggagctccc ggcatgtcgc aagggctccc ggccgccggc 250

 agcgtcctgc agaggagcgt cgcggcgccc gggaaccagc cgcagccgca 300

 gccgcagcag cagagccctg aggatgatga caggaaggtc cgaaggagag 350

 aaaaaaaccg agttgctgct cagagaagtc ggaagaagca gacccagaag 400

 gctgacaagc tccatgagga atatgagagc ctggagcaag aaaacaccat 450

 gctgcggaga gagatcggga agctgacaga ggagctgaag cacctgacag 500

 aggcactgaa ggagcacgag aagatgtgcc cgctgctgct ctgccctatg 550

 aactttgtgc cagtgcctcc ccggccggac cctgtggccg gctgcttgcc 600

 ccgatgaagc cggggacact cctctgccca gcaaggagcc ttggtcattt 650

 tcatacctgg gaggaaggct tttccttcac aattgtatac agggggcacc 700

 tgtggccagg cctcctcctg ggagctccag gaccagccag ctgtgttccc 750

 tgcagactgg gctcagcccg acatccaaca ggcgccaaac tcacagagcc 800

 cttgtgcaga tccagcatgg aggccaccct caggagtgac ttctcatcca 850

 ccctggcagc tagtaggttc tgctgttatg cagagccatt tcctctagaa 900

 tttggataat aaagatgctt attgtctctc ccttctccag ttctgggaat 950

 ttacaggcac aatacacttc cttttcctgg 980

<210> 3526
<211> 127
<212> PRT
<213> Homo sapien

<400> 3526
 Met Ser Gln Gly Leu Pro Ala Ala Gly Ser Val Leu Gln Arg Ser
   1               5                  10                  15

 Val Ala Ala Pro Gly Asn Gln Pro Gln Pro Gln Pro Gln Gln Gln
                  20                  25                  30

 Ser Pro Glu Asp Asp Asp Arg Lys Val Arg Arg Arg Glu Lys Asn
                  35                  40                  45

 Arg Val Ala Ala Gln Arg Ser Arg Lys Lys Gln Thr Gln Lys Ala
                  50                  55                  60

 Asp Lys Leu His Glu Glu Tyr Glu Ser Leu Glu Gln Glu Asn Thr
                  65                  70                  75

 Met Leu Arg Arg Glu Ile Gly Lys Leu Thr Glu Glu Leu Lys His
                  80                  85                  90

 Leu Thr Glu Ala Leu Lys Glu His Glu Lys Met Cys Pro Leu Leu
                  95                 100                 105

 Leu Cys Pro Met Asn Phe Val Pro Val Pro Pro Arg Pro Asp Pro
                 110                 115                 120

 Val Ala Gly Cys Leu Pro Arg
                 125

<210> 3527
<211> 2071
<212> DNA
<213> Homo sapien

<400> 3527
 catcaccctt tttaacattg tttacacatc actgcctgtt ttagccatgg 50

 ggatttttga ccaggatgtg agtgaccaga acagcgtgga ctgtccccag 100

 ctctacaaac caggacagct gaatctgctt tttaacaagc gtaaattttc 150

 catttgcgtg ttgcatggaa tctacacctc attagtcctt ttcttcatcc 200

 cctatggggc cttttacaac gtggctggag aagatgggca acatattgct 250

 gactaccagt cctctgcagt tacatggcca catctttggt cattgtggtc 300

 agtgtgcaga tagccttgga taccagttac tggactttca ttaatcacgt 350

 cttcatctgg gggagcattg ccatttattt ctccatttta tttacaatgc 400

 acagtaatgg catctttggc atcttcccaa accagtttcc atttgttggt 450

 aatgcacgac attccctgac ccagaagtgc atctggcttg taattctctt 500

 aacaacagtg gcttcagtta tgccagtggt ggcattcaga tttttgaagg 550

 tggatttata cccaaccctg agtgatcaga tccgccggtg gcagaaggct 600

 caaaagaagg caaggcctcc aagtagccga aggcctcgga cccgcaggtc 650

 aagctcaaga aggtctggat atgcttttgc tcaccaagaa ggctatggag 700

 agcttatcac atctggaaaa aatatgcgag ctaaaaatcc acccccaaca 750

 tcagggctgg aaaagacaca ttataatagc actagctgga ttgaaaattt 800

 atgtaagaaa accacagaca ccgtgagcag ctttagccag gataaaacag 850

 tgaaactgtg agtcaatatg aatttaaacc acgtagttat cttttcactt 900

 caggtggagc tgaaattctg ctggctccag agtttgagat ttgaggcaag 950

 aggtggggca ggcagattgc ctcacttaac ttaaatctgc ggcagacaac 1000

 tgccagtgcc catcaaacag gagtgtgcgc tatggaaaac caggccagag 1050

 ggtcactgtc tggtttgtga tttggtggac aaaacactcg ctgttacaag 1100

 tacagatttt tttttttttt aaatcaacct agataccaat tgacctgaac 1150

 tttagaatct tatttatgga gaaaaacttg taaagctgca tattcactga 1200

 atggatcctc aggcggataa aagggtgcat tttaaaggta tatatccaag 1250

 ctgaaaagca tgcctattga cagataaaca tgtatctgta agatcagcct 1300

 ttcccaaggt atacttttaa aatttaaagc gtgtactgtg ttgctttcag 1350

 actgagttgc atgtcactct ttagtcttga tatctacctg tctgttcagc 1400

 caggacaaca aatggcttcc aagcctgaag aatacaaaag tgtgcttgtg 1450

 tttctcattt ttataccagt ctagggacaa aggagactga acatctttgc 1500

 agcaggatag gctggtaatt tgatcaaatt tattcaaaaa gctctcagtc 1550

 tgtgtcatgt aaggacatgc ttatgaaatg tgagagaggc tcgccactaa 1600

 gtattctaaa tacttttcaa tggcttttct aacaacctca gtagtaattt 1650

 gctgagcatc atccagacca ttaatagaat cagcaaagca ctggaatttc 1700

 acactttaat gataatattc cacatagtct atgggcaaat attttcaaca 1750

 tttccaattt ttaaagcttc agaattgaag ccaaacaaat taataaataa 1800

 ttgttttaat tactatttaa aaactcaggt ttagattgtt taaaattagt 1850

 tgcttttgat actcagctgt catgtttata attcaaacat gtagtaaaca 1900

 tatgtaggta aggttgtttt tttggagatg ttgcagctca aatttcagtc 1950

 cacatatgaa tcatcagtgt attttccata aagtgattcg ggcatatttg 2000

 tgtgaaaacc tcagttctgt cacttcttac ctctataaac ttggacgata 2050

 atgaaaaaaa aaaaaaaaaa a 2071

<210> 3528
<211> 195
<212> PRT
<213> Homo sapien

<400> 3528
 Met Ala Thr Ser Leu Val Ile Val Val Ser Val Gln Ile Ala Leu
   1               5                  10                  15

 Asp Thr Ser Tyr Trp Thr Phe Ile Asn His Val Phe Ile Trp Gly
                  20                  25                  30

 Ser Ile Ala Ile Tyr Phe Ser Ile Leu Phe Thr Met His Ser Asn
                  35                  40                  45

 Gly Ile Phe Gly Ile Phe Pro Asn Gln Phe Pro Phe Val Gly Asn
                  50                  55                  60

 Ala Arg His Ser Leu Thr Gln Lys Cys Ile Trp Leu Val Ile Leu
                  65                  70                  75

 Leu Thr Thr Val Ala Ser Val Met Pro Val Val Ala Phe Arg Phe
                  80                  85                  90

 Leu Lys Val Asp Leu Tyr Pro Thr Leu Ser Asp Gln Ile Arg Arg
                  95                 100                 105

 Trp Gln Lys Ala Gln Lys Lys Ala Arg Pro Pro Ser Ser Arg Arg
                 110                 115                 120

 Pro Arg Thr Arg Arg Ser Ser Ser Arg Arg Ser Gly Tyr Ala Phe
                 125                 130                 135

 Ala His Gln Glu Gly Tyr Gly Glu Leu Ile Thr Ser Gly Lys Asn
                 140                 145                 150

 Met Arg Ala Lys Asn Pro Pro Pro Thr Ser Gly Leu Glu Lys Thr
                 155                 160                 165

 His Tyr Asn Ser Thr Ser Trp Ile Glu Asn Leu Cys Lys Lys Thr
                 170                 175                 180

 Thr Asp Thr Val Ser Ser Phe Ser Gln Asp Lys Thr Val Lys Leu
                 185                 190                 195

<210> 3529
<211> 2487
<212> DNA
<213> Homo sapien

<400> 3529
 ggcgagcttc ttggcctaag ggcaggaaga gatggcagcg ggggagacgc 50

 agctctacgc caaggtctcc aacaagctca agagccgcag cagcccctcg 100

 ctcctggagc ccctcctggc catgggcttc ccggtgcaca ccgcgctgaa 150

 agcgttggca gccacgggga ggaagacggc ggaggaggcc ttggcctggc 200

 tgcatgatca ttgcaatgac ccttccctag acgaccccat cccccaggag 250

 tatgcccttt tcctctgtcc aacggggccc ctgctggaaa aacttcaaga 300

 gttctggaga gagagcaagc gccagtgtgc aaagaacaga gctcatgagg 350

 tcttcccaca cgtgacactc tgtgacttct tcacgtgtga agaccagaag 400

 gtggaatgcc tgtacgaggc gctgaagaga gctggagaca ggctcctggg 450

 ctccttcccc acggccgtgc ctctggctct ccactcctcc atcagctacc 500

 tcggcttctt cgtcagtggc agccccgcag acgtcatccg ggaattcgcc 550

 atgaccttcg ccacggaagc atctctctta gcaggcactt ccgtttcccg 600

 cttctggatt ttcagccagg tgcctggaca tggccctaac ctgaggctga 650

 gcaatttaac tagagcctcc ttcgtgagcc actacatcct tcaaaaatac 700

 tgctccgtga agccttgcac caaacagctg catctgacct tggcccacaa 750

 gttctacccc caccaccaga ggacgctgga gcagctggcc agagccatcc 800

 ccctgggcca cagctgccag tggaccgcag cactctactc ccgagacatg 850

 cgctttgtgc actaccagac cctgagagcc ctattccagt acaaacccca 900

 gaacgtggat gagctgacgc taagtcctgg tgactacatc tttgtggacc 950

 ccacgcagca ggacgaagcc agcgagggct gggtgattgg gatctcacag 1000

 cggacgggct gccggggctt cctgccggaa aactacacgg atcgagccag 1050

 tgagtctgac acgtgggtga agcacaggat gtacaccttc agtctagcca 1100

 cagacctgaa ctccagaaag gatggtgaag ccagcagcag atgcagcggg 1150

 gaatttcttc cacaaacggc aaggagtctt agcagcttac aggccttgca 1200

 ggctaccgtt gcaaggaaga gcgtgctggt ggttcgccac ggggagagag 1250

 tggatcagat cttcgggaag gcatggctgc agcaatgctc cactcctgat 1300

 gggaaatact acaggccaga cctgaatttc ccctgcagtc tgccaagacg 1350

 gagtcgtggg atcaaagact ttgaaaacga tcccccatta tcatcgtgtg 1400

 gcattttcca gtccagaatt gcaggggacg cgctactgga cagtggtatc 1450

 agaatcagct ctgtgtttgc ctccccagcc ctccgctgtg tgcagacggc 1500

 caaactcatc ctggaagaac tcaaactgga gaaaaaaatc aagatacgag 1550

 tggaacctgg aatctttgaa tggacaaaat gggaagctgg caaaaccacc 1600

 ccaaccctca tgagcctgga agagctgaaa gaggcaaatt tcaacattga 1650

 cactgattac aggcccgcgt ttcccctgtc cgccctcatg ccggccgaga 1700

 gctaccagga gtacatggac aggtgcacgg cgagcatggt gcaaatcgtc 1750

 aacacctgtc cacaggacac gggtgtcatc ctaattgtga gtcacggctc 1800

 cactctggac tcctgcacgc ggccactgct cgggctgccg ccccgggaat 1850

 gtggggattt tgcccaactc gtgagaaaga tcccttccct gggcatgtgc 1900

 ttctgtgaag aaaataaaga ggaaggaaaa tgggagttgg tgaacccacc 1950

 ggtgaagacc ctgacccacg gggcgaacgc agcatttaac tggaggaact 2000

 ggatctcagg caactgagag ccacggtgat gttgtcataa cctcagagtg 2050

 gagaggcaga aaccatgtgc agaggctggg agatgctgct gtttccagag 2100

 gcgtcttagt ctcacccaat gtgatttgta gaagcacgag acgcactttt 2150

 atatcccgga atatttccct ccggctttcg cctttgtaac tcccatctgt 2200

 ggacccatcg tccaccagcc cagctgcggg gagcacaggg caggtggctg 2250

 ggtgaggatg ccgccctgca gcatgtacac cgagtgtctg cagctgggga 2300

 cacaactgcc cgggactcta acttccagga attaaagact caccacacac 2350

 gaaggatcta accacttcat tttccatggt ctaatcatta aattcccaat 2400

 cgttttttct ttttctgggt ccatcactct ttagccatat ccacatgggc 2450

 taaaacaggt gtaatagtca ataaaatggt cccagaa 2487

<210> 3530
<211> 661
<212> PRT
<213> Homo sapien

<400> 3530
 Met Ala Ala Gly Glu Thr Gln Leu Tyr Ala Lys Val Ser Asn Lys
   1               5                  10                  15

 Leu Lys Ser Arg Ser Ser Pro Ser Leu Leu Glu Pro Leu Leu Ala
                  20                  25                  30

 Met Gly Phe Pro Val His Thr Ala Leu Lys Ala Leu Ala Ala Thr
                  35                  40                  45

 Gly Arg Lys Thr Ala Glu Glu Ala Leu Ala Trp Leu His Asp His
                  50                  55                  60

 Cys Asn Asp Pro Ser Leu Asp Asp Pro Ile Pro Gln Glu Tyr Ala
                  65                  70                  75

 Leu Phe Leu Cys Pro Thr Gly Pro Leu Leu Glu Lys Leu Gln Glu
                  80                  85                  90

 Phe Trp Arg Glu Ser Lys Arg Gln Cys Ala Lys Asn Arg Ala His
                  95                 100                 105

 Glu Val Phe Pro His Val Thr Leu Cys Asp Phe Phe Thr Cys Glu
                 110                 115                 120

 Asp Gln Lys Val Glu Cys Leu Tyr Glu Ala Leu Lys Arg Ala Gly
                 125                 130                 135

 Asp Arg Leu Leu Gly Ser Phe Pro Thr Ala Val Pro Leu Ala Leu
                 140                 145                 150

 His Ser Ser Ile Ser Tyr Leu Gly Phe Phe Val Ser Gly Ser Pro
                 155                 160                 165

 Ala Asp Val Ile Arg Glu Phe Ala Met Thr Phe Ala Thr Glu Ala
                 170                 175                 180

 Ser Leu Leu Ala Gly Thr Ser Val Ser Arg Phe Trp Ile Phe Ser
                 185                 190                 195

 Gln Val Pro Gly His Gly Pro Asn Leu Arg Leu Ser Asn Leu Thr
                 200                 205                 210

 Arg Ala Ser Phe Val Ser His Tyr Ile Leu Gln Lys Tyr Cys Ser
                 215                 220                 225

 Val Lys Pro Cys Thr Lys Gln Leu His Leu Thr Leu Ala His Lys
                 230                 235                 240

 Phe Tyr Pro His His Gln Arg Thr Leu Glu Gln Leu Ala Arg Ala
                 245                 250                 255

 Ile Pro Leu Gly His Ser Cys Gln Trp Thr Ala Ala Leu Tyr Ser
                 260                 265                 270

 Arg Asp Met Arg Phe Val His Tyr Gln Thr Leu Arg Ala Leu Phe
                 275                 280                 285

 Gln Tyr Lys Pro Gln Asn Val Asp Glu Leu Thr Leu Ser Pro Gly
                 290                 295                 300

 Asp Tyr Ile Phe Val Asp Pro Thr Gln Gln Asp Glu Ala Ser Glu
                 305                 310                 315

 Gly Trp Val Ile Gly Ile Ser Gln Arg Thr Gly Cys Arg Gly Phe
                 320                 325                 330

 Leu Pro Glu Asn Tyr Thr Asp Arg Ala Ser Glu Ser Asp Thr Trp
                 335                 340                 345

 Val Lys His Arg Met Tyr Thr Phe Ser Leu Ala Thr Asp Leu Asn
                 350                 355                 360

 Ser Arg Lys Asp Gly Glu Ala Ser Ser Arg Cys Ser Gly Glu Phe
                 365                 370                 375

 Leu Pro Gln Thr Ala Arg Ser Leu Ser Ser Leu Gln Ala Leu Gln
                 380                 385                 390

 Ala Thr Val Ala Arg Lys Ser Val Leu Val Val Arg His Gly Glu
                 395                 400                 405

 Arg Val Asp Gln Ile Phe Gly Lys Ala Trp Leu Gln Gln Cys Ser
                 410                 415                 420

 Thr Pro Asp Gly Lys Tyr Tyr Arg Pro Asp Leu Asn Phe Pro Cys
                 425                 430                 435

 Ser Leu Pro Arg Arg Ser Arg Gly Ile Lys Asp Phe Glu Asn Asp
                 440                 445                 450

 Pro Pro Leu Ser Ser Cys Gly Ile Phe Gln Ser Arg Ile Ala Gly
                 455                 460                 465

 Asp Ala Leu Leu Asp Ser Gly Ile Arg Ile Ser Ser Val Phe Ala
                 470                 475                 480

 Ser Pro Ala Leu Arg Cys Val Gln Thr Ala Lys Leu Ile Leu Glu
                 485                 490                 495

 Glu Leu Lys Leu Glu Lys Lys Ile Lys Ile Arg Val Glu Pro Gly
                 500                 505                 510

 Ile Phe Glu Trp Thr Lys Trp Glu Ala Gly Lys Thr Thr Pro Thr
                 515                 520                 525

 Leu Met Ser Leu Glu Glu Leu Lys Glu Ala Asn Phe Asn Ile Asp
                 530                 535                 540

 Thr Asp Tyr Arg Pro Ala Phe Pro Leu Ser Ala Leu Met Pro Ala
                 545                 550                 555

 Glu Ser Tyr Gln Glu Tyr Met Asp Arg Cys Thr Ala Ser Met Val
                 560                 565                 570

 Gln Ile Val Asn Thr Cys Pro Gln Asp Thr Gly Val Ile Leu Ile
                 575                 580                 585

 Val Ser His Gly Ser Thr Leu Asp Ser Cys Thr Arg Pro Leu Leu
                 590                 595                 600

 Gly Leu Pro Pro Arg Glu Cys Gly Asp Phe Ala Gln Leu Val Arg
                 605                 610                 615

 Lys Ile Pro Ser Leu Gly Met Cys Phe Cys Glu Glu Asn Lys Glu
                 620                 625                 630

 Glu Gly Lys Trp Glu Leu Val Asn Pro Pro Val Lys Thr Leu Thr
                 635                 640                 645

 His Gly Ala Asn Ala Ala Phe Asn Trp Arg Asn Trp Ile Ser Gly
                 650                 655                 660

 Asn


<210> 3531
<211> 1696
<212> DNA
<213> Homo sapien

<400> 3531
 agaacagacg tttgaacaga gcaggcttct gaggtctcca aaatgcctgt 50

 cccagcctcc tggccccatc ctcctggtcc tttcctgctt ctgactctac 100

 tgctgggact tacagaagtg gcaggtgagg aggagctaca gatgattcag 150

 cctgagaagc tcctgttggt cacagttgga aagacagcca ctctgcactg 200

 cactgtgacc tccctgcttc ccgtgggacc cgtcctgtgg ttcagaggag 250

 ttggaccagg ccgagaatta atctacaatc aaaaagaagg ccacttcccc 300

 agggtaacaa cagtttcaga cctcacaaag agaaacaaca tggacttttc 350

 catccgcatc agtagcatca ccccagcaga tgtcggcaca tactactgtg 400

 tgaagtttcg aaaagggagc cctgagaacg tggagtttaa gtctggacca 450

 ggcactgaga tggctttggg tgccaaaccc tctgcccccg tggtattggg 500

 ccctgcggcg aggaccacac ctgagcatac agtgagtttc acctgtgagt 550

 cccatggctt ctctcccaga gacatcaccc tgaaatggtt caaaaatggg 600

 aatgagctct cagacttcca gaccaacgtg gaccccacag gacagagtgt 650

 ggcctacagc atccgcagca cagccagggt ggtactggac ccctgggacg 700

 ttcgctctca ggtcatctgc gaggtggccc atgtcacctt gcagggggac 750

 cctcttcgtg ggactgccaa cttgtctgag gccatccgag ttccacccac 800

 cttggaggtt actcaacagc ccatgagggc ggggaaccag gtaaacgtca 850

 cctgccaggt gaggaagttc tacccccaga gcctacagct gacctggttg 900

 gagaatggaa acgtgtgcca gagagaaaca gcctcgaccc ttacagagaa 950

 caaggatggt acctacaact ggacaagctg gttcctggtg aacatatctg 1000

 accaaaggga tgatgtggtc ctcacctgcc aggtgaagca tgatgggcag 1050

 ctggcggtca gcaaacgcct tgccctggag gtcacagtcc accagaagga 1100

 ccagagctca gatgctaccc ctggcccggc atcatctctt actgcgctgc 1150

 tcctcatagc tgtcctcctg ggccccatct atgtcccctg gaagcagaag 1200

 acctgactct ccttccttcc tcccctgcca cgtgggaccc tcatctctgc 1250

 tgcctccttc ctttcctgag aggctcagct tgagagaatg agccagtgag 1300

 aagcttctct agacttggct ccaaacatct cccctcccaa gacatctgcc 1350

 tgcccacagg ctcctgttgc tccttcacac agacctggat gccccagagc 1400

 aaggtcttca ttcatggtcc tgagcagggg ccatgggatt gggctctggg 1450

 cactgactta acggcacctc cctagaaggc gagaaacatg ccaaatctaa 1500

 acacaccagg actcccatcc atcgccttga gactgaccgt aaaccacaga 1550

 cgctctccag gttctcaaga gttatcctgc cttccagatt cctgcctatc 1600

 ccaactcccc agccttgttg aggttctcta ttgcctcttg aatacaaatg 1650

 cactcccaaa gtggttttaa gaaaataaaa agattatcct tccaaa 1696

<210> 3532
<211> 354
<212> PRT
<213> Homo sapien

<400> 3532
 Met Ile Gln Pro Glu Lys Leu Leu Leu Val Thr Val Gly Lys Thr
   1               5                  10                  15

 Ala Thr Leu His Cys Thr Val Thr Ser Leu Leu Pro Val Gly Pro
                  20                  25                  30

 Val Leu Trp Phe Arg Gly Val Gly Pro Gly Arg Glu Leu Ile Tyr
                  35                  40                  45

 Asn Gln Lys Glu Gly His Phe Pro Arg Val Thr Thr Val Ser Asp
                  50                  55                  60

 Leu Thr Lys Arg Asn Asn Met Asp Phe Ser Ile Arg Ile Ser Ser
                  65                  70                  75

 Ile Thr Pro Ala Asp Val Gly Thr Tyr Tyr Cys Val Lys Phe Arg
                  80                  85                  90

 Lys Gly Ser Pro Glu Asn Val Glu Phe Lys Ser Gly Pro Gly Thr
                  95                 100                 105

 Glu Met Ala Leu Gly Ala Lys Pro Ser Ala Pro Val Val Leu Gly
                 110                 115                 120

 Pro Ala Ala Arg Thr Thr Pro Glu His Thr Val Ser Phe Thr Cys
                 125                 130                 135

 Glu Ser His Gly Phe Ser Pro Arg Asp Ile Thr Leu Lys Trp Phe
                 140                 145                 150

 Lys Asn Gly Asn Glu Leu Ser Asp Phe Gln Thr Asn Val Asp Pro
                 155                 160                 165

 Thr Gly Gln Ser Val Ala Tyr Ser Ile Arg Ser Thr Ala Arg Val
                 170                 175                 180

 Val Leu Asp Pro Trp Asp Val Arg Ser Gln Val Ile Cys Glu Val
                 185                 190                 195

 Ala His Val Thr Leu Gln Gly Asp Pro Leu Arg Gly Thr Ala Asn
                 200                 205                 210

 Leu Ser Glu Ala Ile Arg Val Pro Pro Thr Leu Glu Val Thr Gln
                 215                 220                 225

 Gln Pro Met Arg Ala Gly Asn Gln Val Asn Val Thr Cys Gln Val
                 230                 235                 240

 Arg Lys Phe Tyr Pro Gln Ser Leu Gln Leu Thr Trp Leu Glu Asn
                 245                 250                 255

 Gly Asn Val Cys Gln Arg Glu Thr Ala Ser Thr Leu Thr Glu Asn
                 260                 265                 270

 Lys Asp Gly Thr Tyr Asn Trp Thr Ser Trp Phe Leu Val Asn Ile
                 275                 280                 285

 Ser Asp Gln Arg Asp Asp Val Val Leu Thr Cys Gln Val Lys His
                 290                 295                 300

 Asp Gly Gln Leu Ala Val Ser Lys Arg Leu Ala Leu Glu Val Thr
                 305                 310                 315

 Val His Gln Lys Asp Gln Ser Ser Asp Ala Thr Pro Gly Pro Ala
                 320                 325                 330

 Ser Ser Leu Thr Ala Leu Leu Leu Ile Ala Val Leu Leu Gly Pro
                 335                 340                 345

 Ile Tyr Val Pro Trp Lys Gln Lys Thr
                 350

<210> 3533
<211> 2747
<212> DNA
<213> Homo sapien

<400> 3533
 attgattaaa aagagattgc cctgcaaggt aaatcagtta aaaccaacct 50

 ctcctgccct gagtggatag gtagggttag ggttgccaga tgtcacgaag 100

 ttacaggatg ctcagtttta aggtatatcc cttatactat aagggttata 150

 gtaaaaaata ttcattatgt gaaattcaaa tataactggg tatcaggtat 200

 tctatgtggc aaccctaggt aggggagcac aggttaggca agcgattaga 250

 agatttgcag cctccaaagt ttctgcacct cgatgggaca ctagaacagg 300

 aaggctcctg ggcctttctg gctctgggaa tgaagcgtgg aaaaccctcc 350

 ttaggcgggc gcagtgcttc aagtagccaa gctctgactt ccgagggaag 400

 aaaggaggcc atgggcctct gccagagcca tgctctgcac tctggggtca 450

 gcagagttca aaacgacctg caacgtctgg cgcttagctc ctaaagaggt 500

 ctccagtcca gcgccgacgg ccagcggcta gaggccgtcc gcccgactcc 550

 aagatggcgc ccgccacagc tgccaggtgt taagatggcg gcgcggggcc 600

 gcgcccgcgc tcccaggctc tcctccccca gccttcctcc ggctggcagc 650

 acgactcgcg tagccgtgcg ccgattgcct ctcggcctgg gcaatggtcc 700

 cggctgccgg tcgacgaccg ccccgcgtca tgcggctcct cggctggtgg 750

 caagtattgc tgtgggtgct gggacttccc gtccgcggcg tggaggttgc 800

 agaggaaagt ggtcgcttat ggtcggagga gcagcctgct caccctctcc 850

 aggtgggggc tgtgtacctg ggtgaggagg agctcctgca tgacccgatg 900

 ggccaggaca gggcagcaga agaggccaat gcggtgctgg ggctgggcac 950

 ccaaggcgat cacatggtga tgctgtctgt gattcctggg gaagctgagg 1000

 acaaagtgag ttcagagcct agcggcgtca cctgtggtgc tggaggagcg 1050

 gaggactcaa ggtgcaacgt ccgagagagc cttttctctc tggatggcgc 1100

 tggagcacac ttccctgaca gagaagagga gtattacaca gagccagaag 1150

 tggcggaatc tgacgcagcc ccgacagagg actccaataa cactgaaagt 1200

 ctgaaatccc caaaggtgaa ctgtgaggag agaaacatta caggattaga 1250

 aaatttcact ctgaaaattt taaatatgtc acaggacctt atggattttc 1300

 tgaacccaaa cggtagtgac tgtactctag tcctgtttta caccccgtgg 1350

 tgccgctttt ctgccagttt ggcccctcac tttaactctc tgccccgggc 1400

 atttccagct cttcactttt tggcactgga tgcatctcag cacagcagcc 1450

 tttctaccag gtttggcacc gtagctgttc ctaatatttt attatttcaa 1500

 ggagctaaac caatggccag atttaatcat acagatcgaa cactggaaac 1550

 actgaaaatc ttcattttta atcagacagg tatagaagcc aagaagaatg 1600

 tggtggtaac tcaagccgac caaataggcc ctcttcccag cactttgata 1650

 aaaagtgtgg actggttgct tgtattttcc ttattctttt taattagttt 1700

 tattatgtat gctaccattc gaactgagag tattcggtgg ctaattccag 1750

 gacaagagca ggaacatgtg gagtagtgat ggtctgaaag aagttggaaa 1800

 gaggaacttc aatccttcgt ttcagaaatt agtgctacag tttcatacat 1850

 tttctccagt gacgtgttga cttgaaactt caggcagatt aaaagaatca 1900

 tttgttgaac aactgaatgt ataaaaaaaa ttataaactg gtgttttaac 1950

 tagtattgca ataagcaaat gcaaaaatat tcaatagatg cactattctt 2000

 gtttttactg catgaacgta atccagtatt tggaaagtaa tccagtttga 2050

 aatgtgaaga tgtattccgg cagaatagtg agtagaatga catgcttact 2100

 atacagaagg caaaaatagg actctcaggt aatagtttaa ggaaaccctt 2150

 gattccttat atatgtttaa gaaggttagc tttctgtttc tttgcagttt 2200

 ttcttctaga gtccatagca ggaaagtatg taaccagaat tggttagtgt 2250

 gaccccctca agtagcaagt gatggaaaat aagagtcaaa taccttgatg 2300

 tttgtgatct ctaactcaaa aaatttgaag tgttttaagt tgtttctggg 2350

 taagggagat gttaggagaa aggaaatgct gtaactaaag ctcaattatt 2400

 atcagttcta tgctaacgta tacattttaa tcatagttac ctaagcagca 2450

 tgcattaatt gaaccttaaa atgttcccag caggctggtc tcaaactgct 2500

 gacttcaggt gatccacccg cctcggcctc ccaaggtgtt gggattgcag 2550

 gtgtgagcca ctgcgcctgg cctaaacaaa ctttttgaaa agctgtttct 2600

 aaaagattcc ttaaattcag atatgacagc taattacctc atcataaatt 2650

 acttttatac taattgtttc cagggtttta gagtagttga atgtttattt 2700

 cacaaggcac cctaaattct atagaaataa aacctcagat gagtctc 2747

<210> 3534
<211> 360
<212> PRT
<213> Homo sapien

<400> 3534
 Met Val Pro Ala Ala Gly Arg Arg Pro Pro Arg Val Met Arg Leu
   1               5                  10                  15

 Leu Gly Trp Trp Gln Val Leu Leu Trp Val Leu Gly Leu Pro Val
                  20                  25                  30

 Arg Gly Val Glu Val Ala Glu Glu Ser Gly Arg Leu Trp Ser Glu
                  35                  40                  45

 Glu Gln Pro Ala His Pro Leu Gln Val Gly Ala Val Tyr Leu Gly
                  50                  55                  60

 Glu Glu Glu Leu Leu His Asp Pro Met Gly Gln Asp Arg Ala Ala
                  65                  70                  75

 Glu Glu Ala Asn Ala Val Leu Gly Leu Gly Thr Gln Gly Asp His
                  80                  85                  90

 Met Val Met Leu Ser Val Ile Pro Gly Glu Ala Glu Asp Lys Val
                  95                 100                 105

 Ser Ser Glu Pro Ser Gly Val Thr Cys Gly Ala Gly Gly Ala Glu
                 110                 115                 120

 Asp Ser Arg Cys Asn Val Arg Glu Ser Leu Phe Ser Leu Asp Gly
                 125                 130                 135

 Ala Gly Ala His Phe Pro Asp Arg Glu Glu Glu Tyr Tyr Thr Glu
                 140                 145                 150

 Pro Glu Val Ala Glu Ser Asp Ala Ala Pro Thr Glu Asp Ser Asn
                 155                 160                 165

 Asn Thr Glu Ser Leu Lys Ser Pro Lys Val Asn Cys Glu Glu Arg
                 170                 175                 180

 Asn Ile Thr Gly Leu Glu Asn Phe Thr Leu Lys Ile Leu Asn Met
                 185                 190                 195

 Ser Gln Asp Leu Met Asp Phe Leu Asn Pro Asn Gly Ser Asp Cys
                 200                 205                 210

 Thr Leu Val Leu Phe Tyr Thr Pro Trp Cys Arg Phe Ser Ala Ser
                 215                 220                 225

 Leu Ala Pro His Phe Asn Ser Leu Pro Arg Ala Phe Pro Ala Leu
                 230                 235                 240

 His Phe Leu Ala Leu Asp Ala Ser Gln His Ser Ser Leu Ser Thr
                 245                 250                 255

 Arg Phe Gly Thr Val Ala Val Pro Asn Ile Leu Leu Phe Gln Gly
                 260                 265                 270

 Ala Lys Pro Met Ala Arg Phe Asn His Thr Asp Arg Thr Leu Glu
                 275                 280                 285

 Thr Leu Lys Ile Phe Ile Phe Asn Gln Thr Gly Ile Glu Ala Lys
                 290                 295                 300

 Lys Asn Val Val Val Thr Gln Ala Asp Gln Ile Gly Pro Leu Pro
                 305                 310                 315

 Ser Thr Leu Ile Lys Ser Val Asp Trp Leu Leu Val Phe Ser Leu
                 320                 325                 330

 Phe Phe Leu Ile Ser Phe Ile Met Tyr Ala Thr Ile Arg Thr Glu
                 335                 340                 345

 Ser Ile Arg Trp Leu Ile Pro Gly Gln Glu Gln Glu His Val Glu
                 350                 355                 360

<210> 3535
<211> 1327
<212> DNA
<213> Homo sapien

<400> 3535
 tcctagggcg atgttgacag acagacagag gggcggatgc agcctacctc 50

 ctgggcagtg agctgcggtc tgaggcccct gcccagctgg aaaccacagg 100

 gaggggaagg gaggggagga gaggagagga gaggaaccgt catggggcct 150

 tggagtcgag tcagggttgc caaatgccag atgctggtca cctgcttctt 200

 tatcttgctg ctgggcctct ctgtggccac catggtgact cttacctact 250

 tcggggccca ctttgctgtc atccgccgag cgtccctgga gaagaacccg 300

 taccaggctg tgcaccaatg ggccttctct gcggggttga gcctggtggg 350

 cctcctgact ctgggagccg tgctgagcgc tgcagccacc gtgagggagg 400

 cccagggcct catggcaggg ggcttcctgt gcttctccct ggcgttctgc 450

 gcacaggtgc aggtggtgtt ctggagactc cacagcccca cccaggtgga 500

 ggacgccatg ctggacacct acgacctggt atatgagcag gcgatgaaag 550

 gtacgtccca cgtccggcgg caggagctgg cggccatcca ggacgtgttt 600

 ctgtgctgtg ggaagaagtc tcctttcagc cgtctgggga gcacagaggc 650

 tgacctgtgt cagggagagg aggcggcgag agaggactgc cttcagggca 700

 tccggagctt cctgaggaca caccagcagg tcgcctccag cctgaccagc 750

 atcggcctgg ccctcacggt gtccgccttg ctcttcagct ccttcctgtg 800

 gtttgccatc cgctgtggct gcagcttgga ccgcaagggc aaatacaccc 850

 tgaccccacg agcatgtggc cgccagcccc aggagcccag cctcttgaga 900

 tgctcccagg gtggacccac acattgtctc cactccgaag cagttgctat 950

 tggtccaaga ggatgctcgg gtagtcttcg gtggctgcag gagagcgatg 1000

 ctgcgcctct gcccctctcc tgccacctgg ctgcccacag agctctccag 1050

 ggcagaagtc gcggtgggct cagtgggtgc cctgagcggg gtctctcaga 1100

 ctgacgtcag gccttggtgg gctgcactct cacctggagg ctccggggaa 1150

 gcatctgcct ccaggaccat tcaggctgtt gacaagtcaa ctcctcatgg 1200

 ctgtaggact gaggttccca agtccttgtc cctggtcctg tggtccctcc 1250

 accttcaaac cagcaatggt gcattgagca aattgtggtc aaatatacat 1300

 cacatcaaat ttaccatctt aaaaaaa 1327

<210> 3536
<211> 320
<212> PRT
<213> Homo sapien

<400> 3536
 Met Gly Pro Trp Ser Arg Val Arg Val Ala Lys Cys Gln Met Leu
   1               5                  10                  15

 Val Thr Cys Phe Phe Ile Leu Leu Leu Gly Leu Ser Val Ala Thr
                  20                  25                  30

 Met Val Thr Leu Thr Tyr Phe Gly Ala His Phe Ala Val Ile Arg
                  35                  40                  45

 Arg Ala Ser Leu Glu Lys Asn Pro Tyr Gln Ala Val His Gln Trp
                  50                  55                  60

 Ala Phe Ser Ala Gly Leu Ser Leu Val Gly Leu Leu Thr Leu Gly
                  65                  70                  75

 Ala Val Leu Ser Ala Ala Ala Thr Val Arg Glu Ala Gln Gly Leu
                  80                  85                  90

 Met Ala Gly Gly Phe Leu Cys Phe Ser Leu Ala Phe Cys Ala Gln
                  95                 100                 105

 Val Gln Val Val Phe Trp Arg Leu His Ser Pro Thr Gln Val Glu
                 110                 115                 120

 Asp Ala Met Leu Asp Thr Tyr Asp Leu Val Tyr Glu Gln Ala Met
                 125                 130                 135

 Lys Gly Thr Ser His Val Arg Arg Gln Glu Leu Ala Ala Ile Gln
                 140                 145                 150

 Asp Val Phe Leu Cys Cys Gly Lys Lys Ser Pro Phe Ser Arg Leu
                 155                 160                 165

 Gly Ser Thr Glu Ala Asp Leu Cys Gln Gly Glu Glu Ala Ala Arg
                 170                 175                 180

 Glu Asp Cys Leu Gln Gly Ile Arg Ser Phe Leu Arg Thr His Gln
                 185                 190                 195

 Gln Val Ala Ser Ser Leu Thr Ser Ile Gly Leu Ala Leu Thr Val
                 200                 205                 210

 Ser Ala Leu Leu Phe Ser Ser Phe Leu Trp Phe Ala Ile Arg Cys
                 215                 220                 225

 Gly Cys Ser Leu Asp Arg Lys Gly Lys Tyr Thr Leu Thr Pro Arg
                 230                 235                 240

 Ala Cys Gly Arg Gln Pro Gln Glu Pro Ser Leu Leu Arg Cys Ser
                 245                 250                 255

 Gln Gly Gly Pro Thr His Cys Leu His Ser Glu Ala Val Ala Ile
                 260                 265                 270

 Gly Pro Arg Gly Cys Ser Gly Ser Leu Arg Trp Leu Gln Glu Ser
                 275                 280                 285

 Asp Ala Ala Pro Leu Pro Leu Ser Cys His Leu Ala Ala His Arg
                 290                 295                 300

 Ala Leu Gln Gly Arg Ser Arg Gly Gly Leu Ser Gly Cys Pro Glu
                 305                 310                 315

 Arg Gly Leu Ser Asp
                 320

<210> 3537
<211> 2444
<212> DNA
<213> Homo sapien

<400> 3537
 ggctccgggg gtggcggtcg gacagtgtct agcacgctca gtccgggctt 50

 ggggccccgc ggcggagaag gaggtagagg gggcggcggc ggcggcggcg 100

 gtggtggcgg caccatgttt cttcactcag ttaatctctg gaacctggcg 150

 ttttatgtct tcatggtctt tctggcaacc ctggggctgt gggatgtctt 200

 cttcggcttc gaggagaata agtgcagtat gagctacatg tttgagtacc 250

 cggagtatca gaaaatagaa cttccaaaga aactggcaaa acgctatccc 300

 gcatatgagt tgtatcttta tggagaggga tcctatgctg aagaacacaa 350

 aattctccct ttgacgggta ttccagttct ctttcttcct ggtaatgctg 400

 gaagttataa gcaagttcgt tctattggct ccattgcact tagaaaagca 450

 gaggacattg acttcaagta ccactttgac ttctttagtg tgaacttcaa 500

 tgaagaactg gtggctttgt atggtggaag tcttcagaag cagaccaagt 550

 ttgtacatga atgtattaaa acaattctca aactctataa gggtcaagaa 600

 tttgctccaa aaagtgtggc aataattggt cattctatgg gtggccttgt 650

 tgcaagagca ttgcttacac tgaaaaattt taagcatgat ctgataaatc 700

 ttcttattac acaagccaca cctcatgttg ctcctgtgat gccattagat 750

 cgtttcatta cagattttta tacgactgta aacaactatt ggattctaaa 800

 tgctcgacac ataaatttaa ccacactttc tgtagctgga ggattccggg 850

 attaccaagt tcgttcagga ttgacttttc taccaaaatt aagccatcat 900

 accagtgcct tatctgttgt gagttcagca gtgcctaaga cctgggtctc 950

 aacagaccac ctctccattg tgtggtgtaa acaattgcag ttgactacag 1000

 ttcgagcatt ctttgatctt attggtgctg atactaaaca aataactcaa 1050

 aattccaaga agaaactgtc agttttgtat caccacttta taagacaccc 1100

 atcaaaacat tttgaggaaa atccagctat aatttctgac ttaacaggga 1150

 catctatgtg ggttctagta aaagtgtcca aatggaccta tgtagcttac 1200

 aacgaatctg agaagatata ttttacattt cctcttgaaa atcatagaaa 1250

 aatctacact catgtctatt gtcagagcac tatgctggat acaaatagtt 1300

 ggatttttgc ttgcataaac agcacttcta tgtgcctgca aggggttgat 1350

 ttatcatgga aagctgaact gctgccaaca attaagtatc tgacattaag 1400

 acttcaagac tatccatctt tgtctcatct tgttgtttat gtaccatctg 1450

 ttcgtggaag taagtttgtt gtagattgtg aattctttaa aaaagagaaa 1500

 agatacatac agcttcctgt aactcatctt ttttcctttg gattgtcttc 1550

 aaggaaagtg gtgttaaata caaatggcct atactacaat ctagagcttc 1600

 tgaactttgg acagatatac caagctttta aaatcaacgt ggtaagcaag 1650

 tgctcagcag tcaaagaaga aataaccagt atctatagac ttcatattcc 1700

 ttggtcttat gaagattcac taaccattgc acaggctcca tcttccacag 1750

 aaatttctct gaaactccat attgctcaac cagaaaacaa tacccatgtg 1800

 gcattattta aaatgtacac gtcatcagac tgtcggtacg aggtgacagt 1850

 taagacttcc ttttcacaaa tacttggaca ggttgttgct tagaatatgc 1900

 taccatgttg gataaagaag ccaaaccata caaagttgat ccttttgtaa 1950

 ttatcattaa gtttctgttg gggtaagttt tattatctgt gataatgatt 2000

 ttaattgtgt tttacatgta acattatatt tggttccata atgcaatata 2050

 aattttcata cagatttggc agttgacttg tttcattaaa tgaggttttt 2100

 ttttttctct taggcaaagg tctaataagt atatcaatgt ctacttcaat 2150

 agtatcattt caaaagtaat tattcacttt atgtatatca gtctaaactt 2200

 agactgcctt taatgtttgt aaataggtgt atatggtcca tgatctgtga 2250

 gtatcctaga ttcaaacgca aatcattaca gggtattgat gaaacagtgc 2300

 ctctctgatc acttttaaaa gtatatttta gacctctcta ccctagttaa 2350

 cattccattc ttaatttagt cacattttca gatttttggt taagcatcaa 2400

 tatgtagatc tttttttcca tcattacaac taacttggct ttct 2444

<210> 3538
<211> 592
<212> PRT
<213> Homo sapien

<400> 3538
 Met Phe Leu His Ser Val Asn Leu Trp Asn Leu Ala Phe Tyr Val
   1               5                  10                  15

 Phe Met Val Phe Leu Ala Thr Leu Gly Leu Trp Asp Val Phe Phe
                  20                  25                  30

 Gly Phe Glu Glu Asn Lys Cys Ser Met Ser Tyr Met Phe Glu Tyr
                  35                  40                  45

 Pro Glu Tyr Gln Lys Ile Glu Leu Pro Lys Lys Leu Ala Lys Arg
                  50                  55                  60

 Tyr Pro Ala Tyr Glu Leu Tyr Leu Tyr Gly Glu Gly Ser Tyr Ala
                  65                  70                  75

 Glu Glu His Lys Ile Leu Pro Leu Thr Gly Ile Pro Val Leu Phe
                  80                  85                  90

 Leu Pro Gly Asn Ala Gly Ser Tyr Lys Gln Val Arg Ser Ile Gly
                  95                 100                 105

 Ser Ile Ala Leu Arg Lys Ala Glu Asp Ile Asp Phe Lys Tyr His
                 110                 115                 120

 Phe Asp Phe Phe Ser Val Asn Phe Asn Glu Glu Leu Val Ala Leu
                 125                 130                 135

 Tyr Gly Gly Ser Leu Gln Lys Gln Thr Lys Phe Val His Glu Cys
                 140                 145                 150

 Ile Lys Thr Ile Leu Lys Leu Tyr Lys Gly Gln Glu Phe Ala Pro
                 155                 160                 165

 Lys Ser Val Ala Ile Ile Gly His Ser Met Gly Gly Leu Val Ala
                 170                 175                 180

 Arg Ala Leu Leu Thr Leu Lys Asn Phe Lys His Asp Leu Ile Asn
                 185                 190                 195

 Leu Leu Ile Thr Gln Ala Thr Pro His Val Ala Pro Val Met Pro
                 200                 205                 210

 Leu Asp Arg Phe Ile Thr Asp Phe Tyr Thr Thr Val Asn Asn Tyr
                 215                 220                 225

 Trp Ile Leu Asn Ala Arg His Ile Asn Leu Thr Thr Leu Ser Val
                 230                 235                 240

 Ala Gly Gly Phe Arg Asp Tyr Gln Val Arg Ser Gly Leu Thr Phe
                 245                 250                 255

 Leu Pro Lys Leu Ser His His Thr Ser Ala Leu Ser Val Val Ser
                 260                 265                 270

 Ser Ala Val Pro Lys Thr Trp Val Ser Thr Asp His Leu Ser Ile
                 275                 280                 285

 Val Trp Cys Lys Gln Leu Gln Leu Thr Thr Val Arg Ala Phe Phe
                 290                 295                 300

 Asp Leu Ile Gly Ala Asp Thr Lys Gln Ile Thr Gln Asn Ser Lys
                 305                 310                 315

 Lys Lys Leu Ser Val Leu Tyr His His Phe Ile Arg His Pro Ser
                 320                 325                 330

 Lys His Phe Glu Glu Asn Pro Ala Ile Ile Ser Asp Leu Thr Gly
                 335                 340                 345

 Thr Ser Met Trp Val Leu Val Lys Val Ser Lys Trp Thr Tyr Val
                 350                 355                 360

 Ala Tyr Asn Glu Ser Glu Lys Ile Tyr Phe Thr Phe Pro Leu Glu
                 365                 370                 375

 Asn His Arg Lys Ile Tyr Thr His Val Tyr Cys Gln Ser Thr Met
                 380                 385                 390

 Leu Asp Thr Asn Ser Trp Ile Phe Ala Cys Ile Asn Ser Thr Ser
                 395                 400                 405

 Met Cys Leu Gln Gly Val Asp Leu Ser Trp Lys Ala Glu Leu Leu
                 410                 415                 420

 Pro Thr Ile Lys Tyr Leu Thr Leu Arg Leu Gln Asp Tyr Pro Ser
                 425                 430                 435

 Leu Ser His Leu Val Val Tyr Val Pro Ser Val Arg Gly Ser Lys
                 440                 445                 450

 Phe Val Val Asp Cys Glu Phe Phe Lys Lys Glu Lys Arg Tyr Ile
                 455                 460                 465

 Gln Leu Pro Val Thr His Leu Phe Ser Phe Gly Leu Ser Ser Arg
                 470                 475                 480

 Lys Val Val Leu Asn Thr Asn Gly Leu Tyr Tyr Asn Leu Glu Leu
                 485                 490                 495

 Leu Asn Phe Gly Gln Ile Tyr Gln Ala Phe Lys Ile Asn Val Val
                 500                 505                 510

 Ser Lys Cys Ser Ala Val Lys Glu Glu Ile Thr Ser Ile Tyr Arg
                 515                 520                 525

 Leu His Ile Pro Trp Ser Tyr Glu Asp Ser Leu Thr Ile Ala Gln
                 530                 535                 540

 Ala Pro Ser Ser Thr Glu Ile Ser Leu Lys Leu His Ile Ala Gln
                 545                 550                 555

 Pro Glu Asn Asn Thr His Val Ala Leu Phe Lys Met Tyr Thr Ser
                 560                 565                 570

 Ser Asp Cys Arg Tyr Glu Val Thr Val Lys Thr Ser Phe Ser Gln
                 575                 580                 585

 Ile Leu Gly Gln Val Val Ala
                 590

<210> 3539
<211> 2125
<212> DNA
<213> Homo sapien

<400> 3539
 aatgaaggcc catgtagcaa aatactgatt caatgtaaag caaactttga 50

 aaataagcta atagtcctta aagaaaaact tatttcagat agcaaaagac 100

 aagccaatga actcattagt tttaaaaacc aaagtcaaga aaggctgaat 150

 aagaaaaaga cagattatga aaaagaatta ttggaaaaaa gccggaagtt 200

 ggctttaact gtaaagggca aagaattgag tgaggaagag ttacatgaga 250

 aattcaatca actttggaaa aagtgggtgt gtgatgtatc cacaactctc 300

 ccgcaagtta cagagcctga cattgatttg gattctgaaa acatcctttg 350

 ggagtatttc aaaaacaaga cgaatgtcgt gggtctactg acaaattctg 400

 cagagaagtt tcaaatcaat tatgataaac atatcaaggt gaataagaaa 450

 tataaccata tcccaatgac attaacagtc tttgagaaag agttcattaa 500

 tatgactact gactacattg tttcaagatt taataaaatt attaacaaca 550

 tgtggaaaca acagtgtggt tacaatccaa attatttcca tgagattcta 600

 aagacaatag aagaagaagt gaaatctgcc tctactcaga agagatacac 650

 atttacaaat acatttatca ttgacttatg tgtgtgttta tttcaaagag 700

 caagagagaa ttttaaggaa atgcacaggg cattcaagag agcaaatgat 750

 cctgtaaact acctagaaag taagaaagat gatttcttca cgagttttaa 800

 gatctcctgt caaggagcaa cctccatcaa aacatttgtt gatattctgt 850

 ggtataagct cactcctgca gtctccacta ctatatggga ggacatgacc 900

 tttaaaattg cgggggacat gcgagctacc tgccctgcgt tcaatggaaa 950

 caggactaac ctggagaaac acattctctt ctctctggca gaagaagaaa 1000

 actttgataa ttactgggaa taccttcata attcaaaatc gttttttagg 1050

 agttacatca aaaatcatat taaaagatat tgttcagaca atggaggtga 1100

 aaaaatgaag actttttttg aaaaaagctt aattgatatc aagaatacca 1150

 tcctctctgc catccatgaa tccacatcag tagctaaaga taaaagcagc 1200

 actgcttctg agtggttgga tttattctgt gattgcctgg ggtgcaactt 1250

 gatctttcca cgaagggact tgataagcat tgaacaccag gagataaaac 1300

 atactgaatt tcttaaagaa gccatgagtg cagctttgga tctcacaatg 1350

 aagaaaatag aacagaatta ttcaagtaag cctatagaag caatggtttc 1400

 taaaattgag aaaatgctct ctgaacatct ctgtggctgc tggaaacagt 1450

 gtcccagctg tggagcaatt tgtacaaaca caattcctac acatgaagga 1500

 gaccatagtg ttcccttcca ccgtcctcag gctgtcaatg gggaggaatg 1550

 gtatgaaaca gatgattttg tcattgattg ctgtactagt ttggttgcaa 1600

 gtgattgttt gttggttttg agggatggca ggaatttccc atttaagaac 1650

 tatcgacaag caggagggga ttatgccatg tggagcatca ccccagatac 1700

 ctccatccag ctatactgga aatggtttgt ctctcacttc agatcaaatc 1750

 tagaagaaaa atatcagaaa aaatttgcag gtaaaggtaa aatccccaat 1800

 gcatgggcca aaatcacaaa gcaagatgtg cttgaagact tgaaaaaaca 1850

 gtaatactca gtgaccacaa aagagcccca gtgtctgaag aaaagaggca 1900

 gtgtacctga acaatccaaa aacaactact cattacaatt agaaccttca 1950

 tcatttccat gtttaaaatg aaatgtgtaa aaatcaatca attaacacat 2000

 taagagatga aaatttccag taaaaggact tcatttctct ctgcctcaat 2050

 tcctctagtt taaaaacaac ttactaaaat ctgttaatat atgatgaaat 2100

 caaataacat tcattttaga aacct 2125

<210> 3540
<211> 462
<212> PRT
<213> Homo sapien

<400> 3540
 Met Thr Leu Thr Val Phe Glu Lys Glu Phe Ile Asn Met Thr Thr
   1               5                  10                  15

 Asp Tyr Ile Val Ser Arg Phe Asn Lys Ile Ile Asn Asn Met Trp
                  20                  25                  30

 Lys Gln Gln Cys Gly Tyr Asn Pro Asn Tyr Phe His Glu Ile Leu
                  35                  40                  45

 Lys Thr Ile Glu Glu Glu Val Lys Ser Ala Ser Thr Gln Lys Arg
                  50                  55                  60

 Tyr Thr Phe Thr Asn Thr Phe Ile Ile Asp Leu Cys Val Cys Leu
                  65                  70                  75

 Phe Gln Arg Ala Arg Glu Asn Phe Lys Glu Met His Arg Ala Phe
                  80                  85                  90

 Lys Arg Ala Asn Asp Pro Val Asn Tyr Leu Glu Ser Lys Lys Asp
                  95                 100                 105

 Asp Phe Phe Thr Ser Phe Lys Ile Ser Cys Gln Gly Ala Thr Ser
                 110                 115                 120

 Ile Lys Thr Phe Val Asp Ile Leu Trp Tyr Lys Leu Thr Pro Ala
                 125                 130                 135

 Val Ser Thr Thr Ile Trp Glu Asp Met Thr Phe Lys Ile Ala Gly
                 140                 145                 150

 Asp Met Arg Ala Thr Cys Pro Ala Phe Asn Gly Asn Arg Thr Asn
                 155                 160                 165

 Leu Glu Lys His Ile Leu Phe Ser Leu Ala Glu Glu Glu Asn Phe
                 170                 175                 180

 Asp Asn Tyr Trp Glu Tyr Leu His Asn Ser Lys Ser Phe Phe Arg
                 185                 190                 195

 Ser Tyr Ile Lys Asn His Ile Lys Arg Tyr Cys Ser Asp Asn Gly
                 200                 205                 210

 Gly Glu Lys Met Lys Thr Phe Phe Glu Lys Ser Leu Ile Asp Ile
                 215                 220                 225

 Lys Asn Thr Ile Leu Ser Ala Ile His Glu Ser Thr Ser Val Ala
                 230                 235                 240

 Lys Asp Lys Ser Ser Thr Ala Ser Glu Trp Leu Asp Leu Phe Cys
                 245                 250                 255

 Asp Cys Leu Gly Cys Asn Leu Ile Phe Pro Arg Arg Asp Leu Ile
                 260                 265                 270

 Ser Ile Glu His Gln Glu Ile Lys His Thr Glu Phe Leu Lys Glu
                 275                 280                 285

 Ala Met Ser Ala Ala Leu Asp Leu Thr Met Lys Lys Ile Glu Gln
                 290                 295                 300

 Asn Tyr Ser Ser Lys Pro Ile Glu Ala Met Val Ser Lys Ile Glu
                 305                 310                 315

 Lys Met Leu Ser Glu His Leu Cys Gly Cys Trp Lys Gln Cys Pro
                 320                 325                 330

 Ser Cys Gly Ala Ile Cys Thr Asn Thr Ile Pro Thr His Glu Gly
                 335                 340                 345

 Asp His Ser Val Pro Phe His Arg Pro Gln Ala Val Asn Gly Glu
                 350                 355                 360

 Glu Trp Tyr Glu Thr Asp Asp Phe Val Ile Asp Cys Cys Thr Ser
                 365                 370                 375

 Leu Val Ala Ser Asp Cys Leu Leu Val Leu Arg Asp Gly Arg Asn
                 380                 385                 390

 Phe Pro Phe Lys Asn Tyr Arg Gln Ala Gly Gly Asp Tyr Ala Met
                 395                 400                 405

 Trp Ser Ile Thr Pro Asp Thr Ser Ile Gln Leu Tyr Trp Lys Trp
                 410                 415                 420

 Phe Val Ser His Phe Arg Ser Asn Leu Glu Glu Lys Tyr Gln Lys
                 425                 430                 435

 Lys Phe Ala Gly Lys Gly Lys Ile Pro Asn Ala Trp Ala Lys Ile
                 440                 445                 450

 Thr Lys Gln Asp Val Leu Glu Asp Leu Lys Lys Gln
                 455                 460

<210> 3541
<211> 1817
<212> DNA
<213> Homo sapien

<400> 3541
 gtgcggagcc gcccgtaaga tgctctgacc tttgaccctg ccgttcagct 50

 ctagggcccg tgcaggccac accatgaaca cctccccagg cacggtgggc 100

 agtgacccgg tcatcctggc cactgcaggc tacgaccaca ccgtgcgctt 150

 ctggcaggcc cacagcggca tctgcacccg gacggtgcag caccaggact 200

 cccaggtgaa tgccttggag gtcacaccgg accgcagcat gattgctgct 250

 gcaggttacc agcacatccg catgtatgat ctcaactcca ataaccctaa 300

 ccccatcatc agctacgacg gcgtcaacaa gaacatcgcg tctgtgggct 350

 tccacgaaga cggccgctgg atgtacacgg gcggcgagga ctgcacagcc 400

 aggatctggg acctcaggtc ccggaacctg cagtgccagc ggatcttcca 450

 ggtgaacgca cccattaact gcgtgtgcct gcacccgaac caggcagagc 500

 tcatcgtggg tgaccagagc ggggctatcc acatctggga cttgaaaaca 550

 gaccacaacg agcagctgat ccctgagccc gaggtctcca tcacgtccgc 600

 ccacatcgat cccgacgcca gctacatggc agctgtcaat agcaccggaa 650

 actgctatgt ctggaatctg acggggggca ttggtgacga ggtgacccag 700

 ctcatcccca agactaagat ccctgcccac acgcgctacg ccctgcagtg 750

 tcgcttcagc cccgactcca cgctcctcgc cacctgctcg gctgatcaga 800

 cgtgcaagat ctggaggacg tccaacttct ccctgatgac ggagctgagc 850

 atcaagagcg gcaaccccgg ggagtcctcc cgcggctgga tgtggggctg 900

 cgccttctcg ggggactccc agtacatcgt cactggtgag ccccgccctg 950

 gcctccccca tccctggccc ccggcgctgg cctccagagc cagcccacct 1000

 cggctgcagc ttcccctctg ctggggccgc ctgcttggcc tgcacctgcg 1050

 ctcttagccc tgcacaatct ccccctccag cttcctcgga caacctggcc 1100

 cggctctggt gtgtggagac tggagagatc aagagagagt atggcggcca 1150

 ccagaaggct gttgtctgcc tggccttcaa tgacagtgtg ctgggctagc 1200

 ctgtgacccc tcgggactgc ctggtgcagg tggtggcagc tggagggacc 1250

 catgcagcac ccaggtcaga gcagaccctc ccctgccggc ctgcgccagc 1300

 tggacctgat ggccccctgt ggcgccttga cctgctgggc caggctgccc 1350

 tgggactctc agcccccagt tgcttatcca gatgtgacag agctcgaccc 1400

 aagccaggct gcacactcct ggactgggct agcctgcact gcctgggaaa 1450

 gtcggccgag ggcccaaagc tgctgagggg tctgaggctg gtgcccaccc 1500

 ccaagctagt gcgttctctg cccctccctg cccgcgtttc agggcctcgg 1550

 tccatagaga acaccaccac catggccagg tggaagggtt tattagtccc 1600

 tgccagcagc tgtcctccct ggtgcaggtg gcctggccag cccactggat 1650

 tggggacggg ccaggctggg ccaggtcggg ggctcagtct gggaggtaat 1700

 aaaagcagac cgacacgcag atgttgctcg ggaaaaaaaa aaaaaaaaaa 1750

 aaaaaaacca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaaaaaaaaa aaaaaaa 1817

<210> 3542
<211> 327
<212> PRT
<213> Homo sapien

<400> 3542
 Met Asn Thr Ser Pro Gly Thr Val Gly Ser Asp Pro Val Ile Leu
   1               5                  10                  15

 Ala Thr Ala Gly Tyr Asp His Thr Val Arg Phe Trp Gln Ala His
                  20                  25                  30

 Ser Gly Ile Cys Thr Arg Thr Val Gln His Gln Asp Ser Gln Val
                  35                  40                  45

 Asn Ala Leu Glu Val Thr Pro Asp Arg Ser Met Ile Ala Ala Ala
                  50                  55                  60

 Gly Tyr Gln His Ile Arg Met Tyr Asp Leu Asn Ser Asn Asn Pro
                  65                  70                  75

 Asn Pro Ile Ile Ser Tyr Asp Gly Val Asn Lys Asn Ile Ala Ser
                  80                  85                  90

 Val Gly Phe His Glu Asp Gly Arg Trp Met Tyr Thr Gly Gly Glu
                  95                 100                 105

 Asp Cys Thr Ala Arg Ile Trp Asp Leu Arg Ser Arg Asn Leu Gln
                 110                 115                 120

 Cys Gln Arg Ile Phe Gln Val Asn Ala Pro Ile Asn Cys Val Cys
                 125                 130                 135

 Leu His Pro Asn Gln Ala Glu Leu Ile Val Gly Asp Gln Ser Gly
                 140                 145                 150

 Ala Ile His Ile Trp Asp Leu Lys Thr Asp His Asn Glu Gln Leu
                 155                 160                 165

 Ile Pro Glu Pro Glu Val Ser Ile Thr Ser Ala His Ile Asp Pro
                 170                 175                 180

 Asp Ala Ser Tyr Met Ala Ala Val Asn Ser Thr Gly Asn Cys Tyr
                 185                 190                 195

 Val Trp Asn Leu Thr Gly Gly Ile Gly Asp Glu Val Thr Gln Leu
                 200                 205                 210

 Ile Pro Lys Thr Lys Ile Pro Ala His Thr Arg Tyr Ala Leu Gln
                 215                 220                 225

 Cys Arg Phe Ser Pro Asp Ser Thr Leu Leu Ala Thr Cys Ser Ala
                 230                 235                 240

 Asp Gln Thr Cys Lys Ile Trp Arg Thr Ser Asn Phe Ser Leu Met
                 245                 250                 255

 Thr Glu Leu Ser Ile Lys Ser Gly Asn Pro Gly Glu Ser Ser Arg
                 260                 265                 270

 Gly Trp Met Trp Gly Cys Ala Phe Ser Gly Asp Ser Gln Tyr Ile
                 275                 280                 285

 Val Thr Gly Glu Pro Arg Pro Gly Leu Pro His Pro Trp Pro Pro
                 290                 295                 300

 Ala Leu Ala Ser Arg Ala Ser Pro Pro Arg Leu Gln Leu Pro Leu
                 305                 310                 315

 Cys Trp Gly Arg Leu Leu Gly Leu His Leu Arg Ser
                 320                 325

<210> 3543
<211> 4215
<212> DNA
<213> Homo sapien

<400> 3543
 gggcgacacc cgggccgtgc cgccagcgtc cgtcgggaga gtgaaggctc 50

 gcaacgcctt gcccggggga aggtaacgcg ccgcgcccgg ggctgcgcgg 100

 tttgcaccgc caggccgagg gctgggggcc agaagacaag agagacggcg 150

 aggcgcgctc cctgcccggc agcgactcgg aggtaggtga tgctctgatg 200

 ctgctgcctc ttatgaattg acgacaggtg cagagagaga ataaactgtg 250

 tctaagactg gaccagagag tgagtgtgct ggaagccacc ataggaacaa 300

 gcgacctgtt tggcaaggaa tacagcatcc ttctgagagc ctcttctcga 350

 cactatccca cagaccagga cttcctcatg ggaaagagca cttaggatct 400

 tgctatcagc tgccctaaac ttttgctgag ccaaaataag actttgatgc 450

 agaactgaac aagatatttc atttttgtgt gttttaatct tcctggttgc 500

 agtcttagtt gttcagccct gagaattttg agccacattt gttgctatta 550

 tttttgcatg cacttttcaa aatgattgac ttaagcttcc tgactgaaga 600

 ggaacaagag gccatcatga aggttttgca gcgggatgct gctctgaaga 650

 gggccgaaga agagagagtc agacatttgc ctgaaaaaat taaggatgac 700

 cagcagctga agaatatgag tggccaatgg ttttatgaag ccaaggcaaa 750

 aaggcacagg gacaaaatcc atggcgcaga tatcatcaga gcatctatga 800

 gaaagaagag gccccagata gcagctgagc agagtaaaga cagagaaaat 850

 ggggcaaagg aaagctgggt gaataatgtc aacaaagatg ctttccttcc 900

 tccagagctg gctggcgttg tagaagagcc agaagaagat gcagcaccag 950

 caagcccgag ttccagtgtg gtaaatccag cttccagtgt gattgatatg 1000

 tcccaggaaa acacaaggaa accaaatgtg tctccagaga agaggaagaa 1050

 tccgtttaat agctccaagt tgccagaagg tcactcatca caacaaacta 1100

 aaaatgaaca gtcaaaaaat ggaagaactg gtttatttca gacttcaaaa 1150

 gaggatgaat tgtcagagtc aaaagaaaag tcaactgtcg cagatacttc 1200

 aatccaaaag ttagagaaat caaagcagac tttgccaggc ctttcaaatg 1250

 ggtcccaaat caaggctcca atccccaaag ccaggaagat gatctacaaa 1300

 tcaactgatt taaacaaaga tgataaccag tcttttccta gacaaaggac 1350

 agactccctg aaagcgagag gggctccgag agggatcctc aagcgcaact 1400

 ccagttccag tagcacagac tcagaaaccc ttcgttataa tcacaacttt 1450

 gaacccaaaa gcaaaattgt gtcacctggc ctaaccatcc atgagagaat 1500

 ttctgagaag gagcattctt tagaagacaa ctcttcccca aactccctgg 1550

 agccattaaa gcatgtgaga ttctctgcag tgaaggatga gcttccacag 1600

 agtcctgggc taatccatgg tcgggaagta ggagaattta gtgttttaga 1650

 atctgacaga ttgaaaaatg gaatggaaga tgcaggggac acagaagagt 1700

 ttcagagtga ccctaagcct tctcaataca gaaagccttc gctttttcat 1750

 caatcaacct caagcccata tgtatcaaaa agtgaaacac atcagccaat 1800

 gacttctggt tcttttccaa ttaatgggct gcattctcat tcagaagttt 1850

 taactgcaag accacagtct atggagaatt caccaaccat caatgaaccc 1900

 aaagataaat catcagaatt aacaaggctt gaatctgtat tacccagaag 1950

 ccctgctgat gaactgtctc attgtgttga gcctgagcca tctcaggtgc 2000

 caggtggcag ttctagagac cgtcagcaag gttcagaaga agaacccagt 2050

 cctgttttga aaactttgga aaggagtgcc gctaggaaaa tgccttccaa 2100

 aagtctagaa gacatttcat cagattcatc aaatcaagca aaagtagata 2150

 atcagccaga agaattagtg cgtagtgctg aagatgatga gaaaccagat 2200

 cagaagccag ttacaaatga atgcgtacca agaatttcca cagtgcctac 2250

 acaacctgat aatccatttt ctcaccctga caaactcaaa aggatgagca 2300

 agtctgttcc agcatttctc caagatgagg tgagtggcag tgtgatgagt 2350

 gtttatagtg gagactttgg caatctggaa gttaaaggaa atattcagtt 2400

 tgcaattgaa tatgtggagt cactgaagga gttgcatgtt tttgtggccc 2450

 agtgtaagga cttagcagca gcggatgtaa aaaaacagcg ttcagaccca 2500

 tatgtaaagg cctatttgct accagacaaa ggcaaaatgg gcaagaagaa 2550

 aacactcgta gtgaagaaaa ccttgaatcc tgtgtataac gaaatactgc 2600

 ggtataaaat tgaaaaacaa atcttaaaga cacagaaatt gaacctgtcc 2650

 atttggcatc gggatacatt taagcgcaat agtttcctag gggaggtgga 2700

 acttgatttg gaaacatggg actgggataa caaacagaat aaacaattga 2750

 gatggtaccc tctgaagcgg aagacagcac cagttgccct tgaagcagaa 2800

 aacagaggtg aaatgaaact agctctccag tatgtcccag agccagtccc 2850

 tggtaaaaag cttcctacaa ctggagaagt gcacatctgg gtgaaggaat 2900

 gccttgatct accactgcta aggggaagtc atctaaattc ttttgttaaa 2950

 tgtaccatcc ttccagatac aagtaggaaa agtcgccaga agacaagagc 3000

 tgtagggaaa accaccaacc ctatcttcaa ccacactatg gtgtatgatg 3050

 ggttcaggcc tgaagatctg atggaagcct gtgtagagct tactgtctgg 3100

 gaccattaca aattaaccaa ccaatttttg ggaggtcttc gtattggctt 3150

 tggaacaggt aaaagttatg ggactgaagt ggactggatg gactctactt 3200

 cagaggaagt tgctctctgg gagaagatgg taaactcccc caatacttgg 3250

 attgaagcaa cactgcctct cagaatgctt ttgattgcca agatttccaa 3300

 atgagcccaa attccactgg ctcctccact gaaaactact aaaccggtgg 3350

 aatctgatct tgaaaatctg agtaggtgga caaatatcct cactttctat 3400

 ctattgcacc taaggaatac tacacagcat gtaaaagtca atctgcatgt 3450

 gcttctttga ttacaaggcc caagggattt aaatataaca aaatgtgtaa 3500

 tttgtgactc taatattaaa taagatattt gaacaagcta ggaaaattga 3550

 atttctgctg ctgcttcaaa gaaaaagctg ccccagagca ttaaacatgg 3600

 ggtattgtta agaagcaaaa tgttcttgtt tgccatcatg tgtttcacac 3650

 cacaattctg tgccacagtt aagagggtct ggtacccttg caggaccttt 3700

 gtaggttgtg ggaaaaagtc gcagaaagat actcaaagtg gagcagggaa 3750

 tggagacaga catcagtgat gataaaaaaa aaaatggacc ttaagaaact 3800

 atttactctg taatctctaa taaaatatgg aattccatat tagggcaatg 3850

 agactgaaac tactggtgtt tttctgcctt gagaaaacaa acagttaaaa 3900

 caagcctcaa atgtatttta gtgccaccca ctggccatag gtacaattca 3950

 gttgttggct tgttttgact taattctaaa ataggtctca agcctgtatt 4000

 tttatgagtt tattttttta aaaccctgca tatatatgat tgtttttctt 4050

 ataactttac tatatgaaag cagcataaga gtagtcacaa acatgttttg 4100

 caacaaagtt ttaattagaa tgtaagttgc tcagttatac tgttcttctt 4150

 atgtatgtaa aattttcgta ttttgtaaaa acccttagaa taaattatca 4200

 tttgatttaa attgt 4215

<210> 3544
<211> 910
<212> PRT
<213> Homo sapien

<400> 3544
 Met Ile Asp Leu Ser Phe Leu Thr Glu Glu Glu Gln Glu Ala Ile
   1               5                  10                  15

 Met Lys Val Leu Gln Arg Asp Ala Ala Leu Lys Arg Ala Glu Glu
                  20                  25                  30

 Glu Arg Val Arg His Leu Pro Glu Lys Ile Lys Asp Asp Gln Gln
                  35                  40                  45

 Leu Lys Asn Met Ser Gly Gln Trp Phe Tyr Glu Ala Lys Ala Lys
                  50                  55                  60

 Arg His Arg Asp Lys Ile His Gly Ala Asp Ile Ile Arg Ala Ser
                  65                  70                  75

 Met Arg Lys Lys Arg Pro Gln Ile Ala Ala Glu Gln Ser Lys Asp
                  80                  85                  90

 Arg Glu Asn Gly Ala Lys Glu Ser Trp Val Asn Asn Val Asn Lys
                  95                 100                 105

 Asp Ala Phe Leu Pro Pro Glu Leu Ala Gly Val Val Glu Glu Pro
                 110                 115                 120

 Glu Glu Asp Ala Ala Pro Ala Ser Pro Ser Ser Ser Val Val Asn
                 125                 130                 135

 Pro Ala Ser Ser Val Ile Asp Met Ser Gln Glu Asn Thr Arg Lys
                 140                 145                 150

 Pro Asn Val Ser Pro Glu Lys Arg Lys Asn Pro Phe Asn Ser Ser
                 155                 160                 165

 Lys Leu Pro Glu Gly His Ser Ser Gln Gln Thr Lys Asn Glu Gln
                 170                 175                 180

 Ser Lys Asn Gly Arg Thr Gly Leu Phe Gln Thr Ser Lys Glu Asp
                 185                 190                 195

 Glu Leu Ser Glu Ser Lys Glu Lys Ser Thr Val Ala Asp Thr Ser
                 200                 205                 210

 Ile Gln Lys Leu Glu Lys Ser Lys Gln Thr Leu Pro Gly Leu Ser
                 215                 220                 225

 Asn Gly Ser Gln Ile Lys Ala Pro Ile Pro Lys Ala Arg Lys Met
                 230                 235                 240

 Ile Tyr Lys Ser Thr Asp Leu Asn Lys Asp Asp Asn Gln Ser Phe
                 245                 250                 255

 Pro Arg Gln Arg Thr Asp Ser Leu Lys Ala Arg Gly Ala Pro Arg
                 260                 265                 270

 Gly Ile Leu Lys Arg Asn Ser Ser Ser Ser Ser Thr Asp Ser Glu
                 275                 280                 285

 Thr Leu Arg Tyr Asn His Asn Phe Glu Pro Lys Ser Lys Ile Val
                 290                 295                 300

 Ser Pro Gly Leu Thr Ile His Glu Arg Ile Ser Glu Lys Glu His
                 305                 310                 315

 Ser Leu Glu Asp Asn Ser Ser Pro Asn Ser Leu Glu Pro Leu Lys
                 320                 325                 330

 His Val Arg Phe Ser Ala Val Lys Asp Glu Leu Pro Gln Ser Pro
                 335                 340                 345

 Gly Leu Ile His Gly Arg Glu Val Gly Glu Phe Ser Val Leu Glu
                 350                 355                 360

 Ser Asp Arg Leu Lys Asn Gly Met Glu Asp Ala Gly Asp Thr Glu
                 365                 370                 375

 Glu Phe Gln Ser Asp Pro Lys Pro Ser Gln Tyr Arg Lys Pro Ser
                 380                 385                 390

 Leu Phe His Gln Ser Thr Ser Ser Pro Tyr Val Ser Lys Ser Glu
                 395                 400                 405

 Thr His Gln Pro Met Thr Ser Gly Ser Phe Pro Ile Asn Gly Leu
                 410                 415                 420

 His Ser His Ser Glu Val Leu Thr Ala Arg Pro Gln Ser Met Glu
                 425                 430                 435

 Asn Ser Pro Thr Ile Asn Glu Pro Lys Asp Lys Ser Ser Glu Leu
                 440                 445                 450

 Thr Arg Leu Glu Ser Val Leu Pro Arg Ser Pro Ala Asp Glu Leu
                 455                 460                 465

 Ser His Cys Val Glu Pro Glu Pro Ser Gln Val Pro Gly Gly Ser
                 470                 475                 480

 Ser Arg Asp Arg Gln Gln Gly Ser Glu Glu Glu Pro Ser Pro Val
                 485                 490                 495

 Leu Lys Thr Leu Glu Arg Ser Ala Ala Arg Lys Met Pro Ser Lys
                 500                 505                 510

 Ser Leu Glu Asp Ile Ser Ser Asp Ser Ser Asn Gln Ala Lys Val
                 515                 520                 525

 Asp Asn Gln Pro Glu Glu Leu Val Arg Ser Ala Glu Asp Asp Glu
                 530                 535                 540

 Lys Pro Asp Gln Lys Pro Val Thr Asn Glu Cys Val Pro Arg Ile
                 545                 550                 555

 Ser Thr Val Pro Thr Gln Pro Asp Asn Pro Phe Ser His Pro Asp
                 560                 565                 570

 Lys Leu Lys Arg Met Ser Lys Ser Val Pro Ala Phe Leu Gln Asp
                 575                 580                 585

 Glu Val Ser Gly Ser Val Met Ser Val Tyr Ser Gly Asp Phe Gly
                 590                 595                 600

 Asn Leu Glu Val Lys Gly Asn Ile Gln Phe Ala Ile Glu Tyr Val
                 605                 610                 615

 Glu Ser Leu Lys Glu Leu His Val Phe Val Ala Gln Cys Lys Asp
                 620                 625                 630

 Leu Ala Ala Ala Asp Val Lys Lys Gln Arg Ser Asp Pro Tyr Val
                 635                 640                 645

 Lys Ala Tyr Leu Leu Pro Asp Lys Gly Lys Met Gly Lys Lys Lys
                 650                 655                 660

 Thr Leu Val Val Lys Lys Thr Leu Asn Pro Val Tyr Asn Glu Ile
                 665                 670                 675

 Leu Arg Tyr Lys Ile Glu Lys Gln Ile Leu Lys Thr Gln Lys Leu
                 680                 685                 690

 Asn Leu Ser Ile Trp His Arg Asp Thr Phe Lys Arg Asn Ser Phe
                 695                 700                 705

 Leu Gly Glu Val Glu Leu Asp Leu Glu Thr Trp Asp Trp Asp Asn
                 710                 715                 720

 Lys Gln Asn Lys Gln Leu Arg Trp Tyr Pro Leu Lys Arg Lys Thr
                 725                 730                 735

 Ala Pro Val Ala Leu Glu Ala Glu Asn Arg Gly Glu Met Lys Leu
                 740                 745                 750

 Ala Leu Gln Tyr Val Pro Glu Pro Val Pro Gly Lys Lys Leu Pro
                 755                 760                 765

 Thr Thr Gly Glu Val His Ile Trp Val Lys Glu Cys Leu Asp Leu
                 770                 775                 780

 Pro Leu Leu Arg Gly Ser His Leu Asn Ser Phe Val Lys Cys Thr
                 785                 790                 795

 Ile Leu Pro Asp Thr Ser Arg Lys Ser Arg Gln Lys Thr Arg Ala
                 800                 805                 810

 Val Gly Lys Thr Thr Asn Pro Ile Phe Asn His Thr Met Val Tyr
                 815                 820                 825

 Asp Gly Phe Arg Pro Glu Asp Leu Met Glu Ala Cys Val Glu Leu
                 830                 835                 840

 Thr Val Trp Asp His Tyr Lys Leu Thr Asn Gln Phe Leu Gly Gly
                 845                 850                 855

 Leu Arg Ile Gly Phe Gly Thr Gly Lys Ser Tyr Gly Thr Glu Val
                 860                 865                 870

 Asp Trp Met Asp Ser Thr Ser Glu Glu Val Ala Leu Trp Glu Lys
                 875                 880                 885

 Met Val Asn Ser Pro Asn Thr Trp Ile Glu Ala Thr Leu Pro Leu
                 890                 895                 900

 Arg Met Leu Leu Ile Ala Lys Ile Ser Lys
                 905                 910

<210> 3545
<211> 1834
<212> DNA
<213> Homo sapien

<400> 3545
 gaaaaatcct tgtggttaac agcagaggct tcagagtgta acctgtactc 50

 gggcctagaa attatttaaa atggcgactg atacgtctca aggtgaactc 100

 gtccatccta aggcactccc acttatagta ggagctcagc tgatccacgc 150

 ggacaagtta ggtgagaagg tagaagatag caccatgccg attcgtcgaa 200

 ctgtgaattc tacccgggaa actcctccca aaagcaagct tgctgaaggg 250

 gaggaagaaa agccagaacc agacataagt tcagaggaat ctgtctccac 300

 tgtagaagaa caagagaatg aaactccacc tgctacttcg agtgaggcag 350

 agcagccaaa gggggaacct gagaatgaag agaaggaaga aaataagtct 400

 tctgaggaaa ccaaaaagga tgagaaagat cagtctaaag aaaaggagaa 450

 gaaagtgaaa aaaacaattc cttcctgggc taccctttct gccagccagc 500

 tagccagggc ccagaaacaa acaccgatgg cttcttcccc acgtcccaag 550

 atggatgcaa tcttaactga ggccattaag gcatgcttcc agaagagtgg 600

 tgcatcagtg gttgctattc gaaaatacat catccataag tatccttctc 650

 tggagctgga gagaaggggt tatctcctta aacaagcact gaaaagagaa 700

 ttaaatagag gagtcatcaa acaggttaaa ggaaaaggtg cttcttggaa 750

 gttttgttgt ggttcagaaa tcaagaaaaa acacctcaga aatccagaaa 800

 acagaaagaa taggagctct gcagtggatc cagaaccaca agtaaaattg 850

 gaggatggtc tcccactggc ctttactcgc ctttgtgaac ctaaagaagc 900

 ttcctacagt ctcatcagga aatatgtgtc tcagtattat cctaagctta 950

 gagtggacat caggcctcag ctgttgaaga acgctctgca gagagcagta 1000

 gagaggggcc agttagaaca gataactggc aaaggtgctt cggggacatt 1050

 ccagctgaag aaatcagggg agaaacccct gcttggtgga agcctgatgg 1100

 aatatgcaat cttgtctgcc attgctgcca tgaatgagcc gaagacctgc 1150

 tctaccactg ctctgaagaa gtatgtccta gagaatcacc caggaaccaa 1200

 ttctaactat caaatgcatt tgctgaaaaa aaccctgcag aaatgcgaaa 1250

 agaatgggtg gatggaacag atctctggga aagggttcag tggcaccttc 1300

 cagctctgtt ttccctatta tcccagccca ggagttctgt ttccgaagaa 1350

 agagccagat gattctagag atgaggatga agatgaagat gagtcatcag 1400

 aagaagactc tgaggatgaa gagccgccac ctaagagaag gttgcagaag 1450

 aaaaccccag ccaagtcccc agggaaggcc gcatctgtga agcagagagg 1500

 gtccaaacct gcacctaaag tctcagctgc ccagcggggg aaagctaggc 1550

 ccttgcctaa gaaagcacct cctaaggcca aaacgcctgc caagaagacc 1600

 agaccctcat ccacagtcat caagaaacct agtggtggct cctcaaagaa 1650

 gcctgcaacc agtgcaagaa aggaagtaaa attgccgggc aagggcaaat 1700

 ccaccatgaa gaagtctttc agagtgaaaa agtaaatttt ataggaaaaa 1750

 agggtatgat gatgaaattc aaaatcttat tttctaagca cttttgatat 1800

 caagcaagtg gcttcctttt tgagatatta aaac 1834

<210> 3546
<211> 554
<212> PRT
<213> Homo sapien

<400> 3546
 Met Ala Thr Asp Thr Ser Gln Gly Glu Leu Val His Pro Lys Ala
   1               5                  10                  15

 Leu Pro Leu Ile Val Gly Ala Gln Leu Ile His Ala Asp Lys Leu
                  20                  25                  30

 Gly Glu Lys Val Glu Asp Ser Thr Met Pro Ile Arg Arg Thr Val
                  35                  40                  45

 Asn Ser Thr Arg Glu Thr Pro Pro Lys Ser Lys Leu Ala Glu Gly
                  50                  55                  60

 Glu Glu Glu Lys Pro Glu Pro Asp Ile Ser Ser Glu Glu Ser Val
                  65                  70                  75

 Ser Thr Val Glu Glu Gln Glu Asn Glu Thr Pro Pro Ala Thr Ser
                  80                  85                  90

 Ser Glu Ala Glu Gln Pro Lys Gly Glu Pro Glu Asn Glu Glu Lys
                  95                 100                 105

 Glu Glu Asn Lys Ser Ser Glu Glu Thr Lys Lys Asp Glu Lys Asp
                 110                 115                 120

 Gln Ser Lys Glu Lys Glu Lys Lys Val Lys Lys Thr Ile Pro Ser
                 125                 130                 135

 Trp Ala Thr Leu Ser Ala Ser Gln Leu Ala Arg Ala Gln Lys Gln
                 140                 145                 150

 Thr Pro Met Ala Ser Ser Pro Arg Pro Lys Met Asp Ala Ile Leu
                 155                 160                 165

 Thr Glu Ala Ile Lys Ala Cys Phe Gln Lys Ser Gly Ala Ser Val
                 170                 175                 180

 Val Ala Ile Arg Lys Tyr Ile Ile His Lys Tyr Pro Ser Leu Glu
                 185                 190                 195

 Leu Glu Arg Arg Gly Tyr Leu Leu Lys Gln Ala Leu Lys Arg Glu
                 200                 205                 210

 Leu Asn Arg Gly Val Ile Lys Gln Val Lys Gly Lys Gly Ala Ser
                 215                 220                 225

 Trp Lys Phe Cys Cys Gly Ser Glu Ile Lys Lys Lys His Leu Arg
                 230                 235                 240

 Asn Pro Glu Asn Arg Lys Asn Arg Ser Ser Ala Val Asp Pro Glu
                 245                 250                 255

 Pro Gln Val Lys Leu Glu Asp Gly Leu Pro Leu Ala Phe Thr Arg
                 260                 265                 270

 Leu Cys Glu Pro Lys Glu Ala Ser Tyr Ser Leu Ile Arg Lys Tyr
                 275                 280                 285

 Val Ser Gln Tyr Tyr Pro Lys Leu Arg Val Asp Ile Arg Pro Gln
                 290                 295                 300

 Leu Leu Lys Asn Ala Leu Gln Arg Ala Val Glu Arg Gly Gln Leu
                 305                 310                 315

 Glu Gln Ile Thr Gly Lys Gly Ala Ser Gly Thr Phe Gln Leu Lys
                 320                 325                 330

 Lys Ser Gly Glu Lys Pro Leu Leu Gly Gly Ser Leu Met Glu Tyr
                 335                 340                 345

 Ala Ile Leu Ser Ala Ile Ala Ala Met Asn Glu Pro Lys Thr Cys
                 350                 355                 360

 Ser Thr Thr Ala Leu Lys Lys Tyr Val Leu Glu Asn His Pro Gly
                 365                 370                 375

 Thr Asn Ser Asn Tyr Gln Met His Leu Leu Lys Lys Thr Leu Gln
                 380                 385                 390

 Lys Cys Glu Lys Asn Gly Trp Met Glu Gln Ile Ser Gly Lys Gly
                 395                 400                 405

 Phe Ser Gly Thr Phe Gln Leu Cys Phe Pro Tyr Tyr Pro Ser Pro
                 410                 415                 420

 Gly Val Leu Phe Pro Lys Lys Glu Pro Asp Asp Ser Arg Asp Glu
                 425                 430                 435

 Asp Glu Asp Glu Asp Glu Ser Ser Glu Glu Asp Ser Glu Asp Glu
                 440                 445                 450

 Glu Pro Pro Pro Lys Arg Arg Leu Gln Lys Lys Thr Pro Ala Lys
                 455                 460                 465

 Ser Pro Gly Lys Ala Ala Ser Val Lys Gln Arg Gly Ser Lys Pro
                 470                 475                 480

 Ala Pro Lys Val Ser Ala Ala Gln Arg Gly Lys Ala Arg Pro Leu
                 485                 490                 495

 Pro Lys Lys Ala Pro Pro Lys Ala Lys Thr Pro Ala Lys Lys Thr
                 500                 505                 510

 Arg Pro Ser Ser Thr Val Ile Lys Lys Pro Ser Gly Gly Ser Ser
                 515                 520                 525

 Lys Lys Pro Ala Thr Ser Ala Arg Lys Glu Val Lys Leu Pro Gly
                 530                 535                 540

 Lys Gly Lys Ser Thr Met Lys Lys Ser Phe Arg Val Lys Lys
                 545                 550

<210> 3547
<211> 4619
<212> DNA
<213> Homo sapien

<400> 3547
 gaaggcgtcc cggcatcggc caagattcta cattgctcat ctgggcatct 50

 gagcctcctt cgaagtttcc tgtcacaact gtcctcttga cagcatggat 100

 gaggaggaag acaatctgtc tctgctgacc gcactgctgg aagaaaatga 150

 gtcagccttg gattgtaatt cagaagaaaa taacttcttg acgcgggaaa 200

 atggcgagcc cgacgcattt gatgagctct ttgatgccga cggcgacggt 250

 gaatcttata cagaagaggc tgatgatgga gaaacaggag agacaagaga 300

 cgaaaaggaa aatctggcca ctctctttgg agatatggag gacttaacag 350

 atgaagaaga agttcccgca tcacagtcaa ctgaaaatag ggtcctccct 400

 gctcctgccc ccaggcgaga gaaaacgaat gaagagttgc aagaggaatt 450

 aaggaatttg caagagcaaa tgaaggcctt acaagagcag ctaaaagtaa 500

 caacaattaa acagacagca agcccagccc gtctgcaaaa atcccctgag 550

 aagtctcccc ggccacctct taaggagagg agagttcaga gaattcagga 600

 gtcaacatgc ttttctgcgg agcttgatgt ccctgcgcta ccaagaacca 650

 agagggtggc tcgaacacca aagccttcac ctccagatcc caaaagctca 700

 tcttcaagga tgacaagtgc accctcccaa cccctacaga cgatttctcg 750

 gaacaaacct agtgggataa ctagaggtca aattgtgggg accccaggaa 800

 gttctgggga aacgactcaa cccatctgtg tggaagcctt ctctggtctg 850

 cggctcaggc ggcctcgagt atcctccaca gaaatgaaca agaaaatgac 900

 cggccgaaaa ctgatcagac tgtctcagat caaggaaaag atggccagag 950

 agaagctgga agaaatagat tgggtgacat ttggggttat attgaagaag 1000

 gttacgccac agagtgtgaa tagtggaaaa accttcagca tatggaaact 1050

 gaatgatctt cgtgacctga cacaatgtgt gtccttgttc ttatttggag 1100

 aagttcacaa agcgctctgg aagacggagc aggggactgt cgtagggatc 1150

 ctcaatgcca accccatgaa gcccaaggat ggttcagagg aggtgtgttt 1200

 atctatcgat catcctcaga aggtcttaat tatgggtgaa gctcttgacc 1250

 tgggaacctg taaagccaag aagaagaatg gagagccgtg cacgcagact 1300

 gtgaatttgc gtgactgtga gtactgtcag taccatgtcc aggctcagta 1350

 caagaagctc agtgcaaagc gtgcggatct gcagtccacc ttctctggag 1400

 gacgaattcc aaagaagttt gcccgcagag gcaccagcct caaagaacgg 1450

 ctgtgccaag atggctttta ctacggaggg gtttcttctg cctcgtatgc 1500

 agcttcaatt gcagcagctg tggctcctaa gaagaagatt caaaccactc 1550

 tgagtaatct ggttgttaag ggcacaaact tgatcatcca ggaaacacgg 1600

 caaaaactcg gaatacccca gaagagcctg tcttgctctg aggagttcaa 1650

 ggaactgatg gacctgccga cgtgtggagc caggaactta aaacaacatt 1700

 tagccaaagc ctcagcttca gggattatgg ggagcccaaa accagccatc 1750

 aagtccatct cggcctcagc actcttgaag caacagaagc agcggatgtt 1800

 ggagatgagg agaaggaaat cagaagaaat acagaagcga tttctgcaga 1850

 gctcaagtga agttgagagc ccagctgtgc catcttcatc aagacagccc 1900

 cctgctcagc ctccacggac aggatccgag ttccccaggc tggagggagc 1950

 cccggccaca atgacgccca agctggggcg aggtgtcttg gaaggagatg 2000

 atgttctctt ttatgatgag tcaccaccac caagaccaaa actgagtgct 2050

 ttagcagaag ccaaaaagtt agctgctatc accaaattaa gggcaaaagg 2100

 ccaggttctt acaaaaacaa acccaaacag cattaagaag aaacaaaagg 2150

 accctcagga catcctggag gtgaaggaac gtgtagaaaa aaacaccatg 2200

 ttttcttctc aagctgagga tgaattggag cctgccagga aaaaaaggag 2250

 agaacaactt gcctatctgg aatctgagga atttcagaaa atcctaaaag 2300

 caaaatcaaa acacacaggc atcctgaaag aggccgaggc tgagatgcag 2350

 gagcgctact ttgagccact ggtgaaaaaa gaacaaatgg aagaaaagat 2400

 gagaaacatc agagaagtga agtgccgtgt cgtgacatgc aagacgtgcg 2450

 cctataccca cttcaagctg ctggagacct gcgtcagtga gcagcatgaa 2500

 taccactggc atgatggtgt gaagaggttt ttcaaatgtc cctgtggaaa 2550

 cagaagcatc tccttggaca gactcccgaa caagcactgc agtaactgtg 2600

 gcctctacaa atgggaacgg gacggaatgc taaaggtatg ccatttgcgt 2650

 actaattttt gactcctttt agtgacccat gctaataatg tggaaccatc 2700

 tcctattaaa atattttcat ttttctagga aaagactggt ccaaagatag 2750

 gaggagaaac tctgttacca agaggagaag aacatgctaa atttctgaac 2800

 agccttaaat aacccgaact tcagacattt tcccacagac ttcctggcct 2850

 cctgtgactc tggaaagcaa aggattggct gtgtattgtc cattgattcc 2900

 tgattgacgc cgtcaaaaac aaatgcttgt taagcccata agctttgcct 2950

 gcttactttc tgccattggg ttggtttgat accacattta acattgacat 3000

 ttaagtggaa aaccaagtta tcattgtctt ttctaagctc agtgtggatg 3050

 attgcattac ttcattcact gaagtttttg cccaaaaatt ggaaggtaaa 3100

 cagagagcta tgtttctgta tcttttggtt atagagtgtt cacttcttta 3150

 tcataacaaa attctagtgt ttatacgaac acccagaggc aaaagaattt 3200

 ggcttaattc tcactccagg taagtagctt aacttctggg cttcagtttt 3250

 ctcatctgta aaatcaggaa gattggacta agtgatcctg aaatgtattt 3300

 tttagcactg gatttctaca aataataaaa ctttcccatc tagataatga 3350

 tgatcacata gtcttgatgt acggacatta aaagccagat ttcttcattc 3400

 aattctgtta tctctgtttt actctttgaa attgatcaag ccactgaatc 3450

 actttgcatt tcagtttata tatagagaga gaaagaaggc tgtctgctct 3500

 tacattattg tggagccctg tgatagaaat atgtaaaatc tcatattatt 3550

 ttttttttaa tttttttatt ttttatgaca gggtctcact atgtcaccct 3600

 ggctggagtg cagtagtgcg atcgcggcac actgcagcct tggcttccct 3650

 gggctcaagc agtcctccca cctcagtctc ccaaatagct aggactacag 3700

 gcgtgcgtga ccaagcccag ctaatttttg cattttttgt agagatgggg 3750

 ttttgccatg ttgctcaggc tggtctcaaa ctcctgagca ctagcaatcc 3800

 acccacctct gtttccaaaa aaaaaaaaaa aatgaaaggt caacccctat 3850

 gcaaattacc acagcaaagg tttcattcag gagattcttc catctgggca 3900

 acctggtttt ccaaatatca tttgacctaa gtgaatgttg atactagcta 3950

 aagattgggt aaattggttg aattattgta ttgaagcttg agctgtagct 4000

 aaaagtaatt taggtttccc ctaagatgtt attatgttag ggacataaca 4050

 cttttgggag gttgttgtgg gagatggttg atttaggttt tcaaaagcta 4100

 gaaataaaat ttacatgcct tagatttcat aaaattctgc tctaattggg 4150

 tggaaggtgc tgtatctaac ttgtgttcct cctaaggtta tgtcctaata 4200

 actattcttt taggagtata cttctacttt atagaaggtt gcttttcttt 4250

 ttaatttttt ctaacaaaga aaagaataaa gtatttatta ataagaacca 4300

 gaaagcactt gaaactgatg tttttaatgg ctcatttagg gtagatttat 4350

 ttatctcatt aacttaaaac agctatgtgt atgaaatagg tcacaacaga 4400

 acttgaacac caggttggtg tctgagcaat ccctttctta tgggaaaaac 4450

 aatgttcttg tttgaacaga gggtatcatt gcagtcagta ttcacgtgta 4500

 tattgttata taagttgtat aatatgcttg taaaggctga gggtgagctg 4550

 tatctggatg cctttttaca atttgatttt aacttttaaa ataaatttaa 4600

 aacataaaaa aaaaaaaaa 4619

<210> 3548
<211> 855
<212> PRT
<213> Homo sapien

<400> 3548
 Met Asp Glu Glu Glu Asp Asn Leu Ser Leu Leu Thr Ala Leu Leu
   1               5                  10                  15

 Glu Glu Asn Glu Ser Ala Leu Asp Cys Asn Ser Glu Glu Asn Asn
                  20                  25                  30

 Phe Leu Thr Arg Glu Asn Gly Glu Pro Asp Ala Phe Asp Glu Leu
                  35                  40                  45

 Phe Asp Ala Asp Gly Asp Gly Glu Ser Tyr Thr Glu Glu Ala Asp
                  50                  55                  60

 Asp Gly Glu Thr Gly Glu Thr Arg Asp Glu Lys Glu Asn Leu Ala
                  65                  70                  75

 Thr Leu Phe Gly Asp Met Glu Asp Leu Thr Asp Glu Glu Glu Val
                  80                  85                  90

 Pro Ala Ser Gln Ser Thr Glu Asn Arg Val Leu Pro Ala Pro Ala
                  95                 100                 105

 Pro Arg Arg Glu Lys Thr Asn Glu Glu Leu Gln Glu Glu Leu Arg
                 110                 115                 120

 Asn Leu Gln Glu Gln Met Lys Ala Leu Gln Glu Gln Leu Lys Val
                 125                 130                 135

 Thr Thr Ile Lys Gln Thr Ala Ser Pro Ala Arg Leu Gln Lys Ser
                 140                 145                 150

 Pro Glu Lys Ser Pro Arg Pro Pro Leu Lys Glu Arg Arg Val Gln
                 155                 160                 165

 Arg Ile Gln Glu Ser Thr Cys Phe Ser Ala Glu Leu Asp Val Pro
                 170                 175                 180

 Ala Leu Pro Arg Thr Lys Arg Val Ala Arg Thr Pro Lys Pro Ser
                 185                 190                 195

 Pro Pro Asp Pro Lys Ser Ser Ser Ser Arg Met Thr Ser Ala Pro
                 200                 205                 210

 Ser Gln Pro Leu Gln Thr Ile Ser Arg Asn Lys Pro Ser Gly Ile
                 215                 220                 225

 Thr Arg Gly Gln Ile Val Gly Thr Pro Gly Ser Ser Gly Glu Thr
                 230                 235                 240

 Thr Gln Pro Ile Cys Val Glu Ala Phe Ser Gly Leu Arg Leu Arg
                 245                 250                 255

 Arg Pro Arg Val Ser Ser Thr Glu Met Asn Lys Lys Met Thr Gly
                 260                 265                 270

 Arg Lys Leu Ile Arg Leu Ser Gln Ile Lys Glu Lys Met Ala Arg
                 275                 280                 285

 Glu Lys Leu Glu Glu Ile Asp Trp Val Thr Phe Gly Val Ile Leu
                 290                 295                 300

 Lys Lys Val Thr Pro Gln Ser Val Asn Ser Gly Lys Thr Phe Ser
                 305                 310                 315

 Ile Trp Lys Leu Asn Asp Leu Arg Asp Leu Thr Gln Cys Val Ser
                 320                 325                 330

 Leu Phe Leu Phe Gly Glu Val His Lys Ala Leu Trp Lys Thr Glu
                 335                 340                 345

 Gln Gly Thr Val Val Gly Ile Leu Asn Ala Asn Pro Met Lys Pro
                 350                 355                 360

 Lys Asp Gly Ser Glu Glu Val Cys Leu Ser Ile Asp His Pro Gln
                 365                 370                 375

 Lys Val Leu Ile Met Gly Glu Ala Leu Asp Leu Gly Thr Cys Lys
                 380                 385                 390

 Ala Lys Lys Lys Asn Gly Glu Pro Cys Thr Gln Thr Val Asn Leu
                 395                 400                 405

 Arg Asp Cys Glu Tyr Cys Gln Tyr His Val Gln Ala Gln Tyr Lys
                 410                 415                 420

 Lys Leu Ser Ala Lys Arg Ala Asp Leu Gln Ser Thr Phe Ser Gly
                 425                 430                 435

 Gly Arg Ile Pro Lys Lys Phe Ala Arg Arg Gly Thr Ser Leu Lys
                 440                 445                 450

 Glu Arg Leu Cys Gln Asp Gly Phe Tyr Tyr Gly Gly Val Ser Ser
                 455                 460                 465

 Ala Ser Tyr Ala Ala Ser Ile Ala Ala Ala Val Ala Pro Lys Lys
                 470                 475                 480

 Lys Ile Gln Thr Thr Leu Ser Asn Leu Val Val Lys Gly Thr Asn
                 485                 490                 495

 Leu Ile Ile Gln Glu Thr Arg Gln Lys Leu Gly Ile Pro Gln Lys
                 500                 505                 510

 Ser Leu Ser Cys Ser Glu Glu Phe Lys Glu Leu Met Asp Leu Pro
                 515                 520                 525

 Thr Cys Gly Ala Arg Asn Leu Lys Gln His Leu Ala Lys Ala Ser
                 530                 535                 540

 Ala Ser Gly Ile Met Gly Ser Pro Lys Pro Ala Ile Lys Ser Ile
                 545                 550                 555

 Ser Ala Ser Ala Leu Leu Lys Gln Gln Lys Gln Arg Met Leu Glu
                 560                 565                 570

 Met Arg Arg Arg Lys Ser Glu Glu Ile Gln Lys Arg Phe Leu Gln
                 575                 580                 585

 Ser Ser Ser Glu Val Glu Ser Pro Ala Val Pro Ser Ser Ser Arg
                 590                 595                 600

 Gln Pro Pro Ala Gln Pro Pro Arg Thr Gly Ser Glu Phe Pro Arg
                 605                 610                 615

 Leu Glu Gly Ala Pro Ala Thr Met Thr Pro Lys Leu Gly Arg Gly
                 620                 625                 630

 Val Leu Glu Gly Asp Asp Val Leu Phe Tyr Asp Glu Ser Pro Pro
                 635                 640                 645

 Pro Arg Pro Lys Leu Ser Ala Leu Ala Glu Ala Lys Lys Leu Ala
                 650                 655                 660

 Ala Ile Thr Lys Leu Arg Ala Lys Gly Gln Val Leu Thr Lys Thr
                 665                 670                 675

 Asn Pro Asn Ser Ile Lys Lys Lys Gln Lys Asp Pro Gln Asp Ile
                 680                 685                 690

 Leu Glu Val Lys Glu Arg Val Glu Lys Asn Thr Met Phe Ser Ser
                 695                 700                 705

 Gln Ala Glu Asp Glu Leu Glu Pro Ala Arg Lys Lys Arg Arg Glu
                 710                 715                 720

 Gln Leu Ala Tyr Leu Glu Ser Glu Glu Phe Gln Lys Ile Leu Lys
                 725                 730                 735

 Ala Lys Ser Lys His Thr Gly Ile Leu Lys Glu Ala Glu Ala Glu
                 740                 745                 750

 Met Gln Glu Arg Tyr Phe Glu Pro Leu Val Lys Lys Glu Gln Met
                 755                 760                 765

 Glu Glu Lys Met Arg Asn Ile Arg Glu Val Lys Cys Arg Val Val
                 770                 775                 780

 Thr Cys Lys Thr Cys Ala Tyr Thr His Phe Lys Leu Leu Glu Thr
                 785                 790                 795

 Cys Val Ser Glu Gln His Glu Tyr His Trp His Asp Gly Val Lys
                 800                 805                 810

 Arg Phe Phe Lys Cys Pro Cys Gly Asn Arg Ser Ile Ser Leu Asp
                 815                 820                 825

 Arg Leu Pro Asn Lys His Cys Ser Asn Cys Gly Leu Tyr Lys Trp
                 830                 835                 840

 Glu Arg Asp Gly Met Leu Lys Val Cys His Leu Arg Thr Asn Phe
                 845                 850                 855

<210> 3549
<211> 2426
<212> DNA
<213> Homo sapien

<400> 3549
 acgcggggat tctgtgtaat tcctatccac agtcacttct gttcattttt 50

 aatgaaaacc tattgctgtt attttctatt atgagttaac ggtgatgtgt 100

 gttttttaaa ttttgtatac ttgctctcac cctaaaatat accttaagag 150

 acttttcccc tgtttttctt tctgctttcc aagactccag gaaaaacagc 200

 ttccatggca cattttgtac agggcacatc tagaatgatt gccgcagaaa 250

 gttctacgga gcataaagag tgtgctgaac catcaacaag aaagaacttg 300

 atgaattctc ttgaacaaaa gataaggtgt ttggaaaaac aaagaaaaga 350

 gctcctggaa gttaaccagc aatgggatca gcaatttaga agtatgaaag 400

 agttatatga aagaaaggta gcagagctga agacgaaact ggacgccgcg 450

 gaaagattcc tcagcacgcg ggagaaggat ccgcatcaga ggcagagaaa 500

 ggacgacagg cagagagagg acgacaggca gcgcgacctg acccgggacc 550

 ggctgcagcg ggaggagaag gaaaaggaac gcctaaatga agaattacat 600

 gaattgaaag aagagaataa acttttaaag ggaaaaaata ctcttgcgaa 650

 caaggaaaag gaacattacg aatgtgaaat aaaacgcctc aataaggctc 700

 ttcaggatgc cttgaatatc aagtgttcat tttccgagga ctgtttgagg 750

 aagtctcgag tggaattctg ccatgaggag atgagaacag aaatggaagt 800

 tctgaagcag caggtgcaaa tatacgaaga agacttcaaa aaggaacgat 850

 cggatcgaga gagacttaat caagagaaag aggagctaca gcaaattaat 900

 gaaacttccc aatcccagtt gaacaggctg aattcccaga taaaagcttg 950

 tcagatggag aaagaaaaac tagaaaagca attaaaacag atgtattgcc 1000

 caccctgtaa ctgcggcttg gttttccacc tgcaagatcc atgggtacca 1050

 acaggccctg gagctgtgca gaagcaacgg gagcacccac cagactgtca 1100

 gtggtatgct cttgaccagc ttccgccaga tgtacaacac aaggcaaatg 1150

 gtttatcctc agtaaagaaa gtccatccgt agaagtacac actaacagag 1200

 agagacaaca ggcaacgagg gagcgtggct gaggaccctc ttctttgttt 1250

 atactgaggc ttgtttctgc cacaaaggca catcatctac cctgttattt 1300

 gtgcctggtc atgttttcct ttggtatgaa tacaggaaaa ggcttctgac 1350

 agctaagatc ctgatcaaat tggaggagcc agttattata caaccaaata 1400

 caacttccag tttccttgaa atgagacttg gcagatggat gatgcacgac 1450

 tccctgaaaa tctcttcagc atattgctgt tggatgcaca aaaatgattc 1500

 tatgatttag gcaactcagt gtttgctgca gggatattgt atgttgattt 1550

 aaagtgcata tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tttcctgggg 1600

 taaaaatttc tgcagttgta aacgtttaac attgctccca ttcttcttcc 1650

 acagggcctt agttctttag ctatttgact acatattgtt gacctcagtg 1700

 atcctaaacg tagaattgaa gaggtgtata tacctcgtta aattaaataa 1750

 gtggttcaat ctgaataaga tggttaattg gaagctattc cttagacaga 1800

 tcatttcttt aagatggtga gaaattgtgc gcctgcatca caagacttga 1850

 ttatgaaaga taaagtcttg ggctgggtgc agtggctcat gcctataatc 1900

 ccagcacttt gggaggctga ggcaggtgga ttgctttgag gccaggagtt 1950

 ctagaccagc ctggccagca tggtgaaacc ccatctctac tataaataca 2000

 aaaattagcc aggctcgtgg cacacaccta taaacccagc tactcaggag 2050

 gcttgaggcg ggaggatcac ttgagcccag ggaggcagag gttgctgtaa 2100

 gttgagatcg ccactgcact ccagcctggg aaatagagtg agcaagactc 2150

 agtgccccct acccacccac tccacaccac caaaaaaaaa aaaaaaaaaa 2200

 aaaggaagac aaagtcctga tgggatgatg atggctatat ggctatgctg 2250

 tgtccatata tacttacaga aatatttcag acatatggat ttatagttaa 2300

 atctgtgttt ttccttccta tggatttgat taattttaat gaaaaactta 2350

 attctgactc ctcaagccaa ttaaaatgaa aatggaattt atttaaaaaa 2400

 aaaaaaaaaa aaaaaaaaaa aaaaaa 2426

<210> 3550
<211> 325
<212> PRT
<213> Homo sapien

<400> 3550
 Met Ala His Phe Val Gln Gly Thr Ser Arg Met Ile Ala Ala Glu
   1               5                  10                  15

 Ser Ser Thr Glu His Lys Glu Cys Ala Glu Pro Ser Thr Arg Lys
                  20                  25                  30

 Asn Leu Met Asn Ser Leu Glu Gln Lys Ile Arg Cys Leu Glu Lys
                  35                  40                  45

 Gln Arg Lys Glu Leu Leu Glu Val Asn Gln Gln Trp Asp Gln Gln
                  50                  55                  60

 Phe Arg Ser Met Lys Glu Leu Tyr Glu Arg Lys Val Ala Glu Leu
                  65                  70                  75

 Lys Thr Lys Leu Asp Ala Ala Glu Arg Phe Leu Ser Thr Arg Glu
                  80                  85                  90

 Lys Asp Pro His Gln Arg Gln Arg Lys Asp Asp Arg Gln Arg Glu
                  95                 100                 105

 Asp Asp Arg Gln Arg Asp Leu Thr Arg Asp Arg Leu Gln Arg Glu
                 110                 115                 120

 Glu Lys Glu Lys Glu Arg Leu Asn Glu Glu Leu His Glu Leu Lys
                 125                 130                 135

 Glu Glu Asn Lys Leu Leu Lys Gly Lys Asn Thr Leu Ala Asn Lys
                 140                 145                 150

 Glu Lys Glu His Tyr Glu Cys Glu Ile Lys Arg Leu Asn Lys Ala
                 155                 160                 165

 Leu Gln Asp Ala Leu Asn Ile Lys Cys Ser Phe Ser Glu Asp Cys
                 170                 175                 180

 Leu Arg Lys Ser Arg Val Glu Phe Cys His Glu Glu Met Arg Thr
                 185                 190                 195

 Glu Met Glu Val Leu Lys Gln Gln Val Gln Ile Tyr Glu Glu Asp
                 200                 205                 210

 Phe Lys Lys Glu Arg Ser Asp Arg Glu Arg Leu Asn Gln Glu Lys
                 215                 220                 225

 Glu Glu Leu Gln Gln Ile Asn Glu Thr Ser Gln Ser Gln Leu Asn
                 230                 235                 240

 Arg Leu Asn Ser Gln Ile Lys Ala Cys Gln Met Glu Lys Glu Lys
                 245                 250                 255

 Leu Glu Lys Gln Leu Lys Gln Met Tyr Cys Pro Pro Cys Asn Cys
                 260                 265                 270

 Gly Leu Val Phe His Leu Gln Asp Pro Trp Val Pro Thr Gly Pro
                 275                 280                 285

 Gly Ala Val Gln Lys Gln Arg Glu His Pro Pro Asp Cys Gln Trp
                 290                 295                 300

 Tyr Ala Leu Asp Gln Leu Pro Pro Asp Val Gln His Lys Ala Asn
                 305                 310                 315

 Gly Leu Ser Ser Val Lys Lys Val His Pro
                 320                 325

<210> 3551
<211> 6792
<212> DNA
<213> Homo sapien

<400> 3551
 ctccagtccg catgctcagt agctgctgcc ggccgggctg cggggcggcg 50

 tccgctgcgc gcctacgggc tgcggtggcg gccgccgcgg cacccggcag 100

 ggcccgccag tccccgcttc cctgctccag agccgccgcc tgggccgggg 150

 cagggcgggc ccggggctcc tccatgctgc cagccgccgg gctgcggagc 200

 cgaccaagtg gctcctgcga tggcggcgga agaggaggct gcggcgggag 250

 gtaaagtgtt gagagaggag aaccagtgca ttgctcctgt ggtttccagc 300

 cgcgtgagtc cagggacaag accaacagct atggggtctt tcagctcaca 350

 catgacagag tttccacgaa aacgcaaagg aagtgattca gacccatccc 400

 aagtggaaga tggtgaacac caagttaaaa tgaaggcctt cagagaagct 450

 catagccaaa ctgaaaagcg gaggagagat aaaatgaata acctgattga 500

 agaactgtct gcaatgatcc ctcagtgcaa ccccatggcg cgtaaactgg 550

 acaaacttac agttttaaga atggctgttc aacacttgag atctttaaaa 600

 ggcttgacaa attcttatgt gggaagtaat tatagaccat catttcttca 650

 ggataatgag ctcagacatt taatccttaa gactgcagaa ggcttcttat 700

 ttgtggttgg atgtgaaaga ggaaaaattc tcttcgtttc taagtcagtc 750

 tccaaaatac ttaattatga tcaggctagt ttgactggac aaagcttatt 800

 tgacttctta catccaaaag atgttgccaa agtaaaggaa caactttctt 850

 cttttgatat ttcaccaaga gaaaagctaa tagatgccaa aactggtttg 900

 caagttcaca gtaatctcca cgctggaagg acacgtgtgt attctggctc 950

 aagacgatct tttttctgtc ggataaagag ttgtaaaatc tctgtcaaag 1000

 aagagcatgg atgcttaccc aactcaaaga agaaagagca cagaaaattc 1050

 tatactatcc attgcactgg ttacttgaga agctggcctc caaatattgt 1100

 tggaatggaa gaagaaagga acagtaagaa agacaacagt aattttacct 1150

 gccttgtggc cattggaaga ttacagccat atattgttcc acagaacagt 1200

 ggagagatta atgtgaaacc aactgaattt ataacccggt ttgcagtgaa 1250

 tggaaaattt gtctatgtag atcaaagggc aacagcgatt ttaggatatc 1300

 tgcctcagga acttttggga acttcttgtt atgaatattt tcatcaagat 1350

 gaccacaata atttgactga caagcacaaa gcagttctac agagtaagga 1400

 gaaaatactt acagattcct acaaattcag agcaaaagat ggctcttttg 1450

 taactttaaa aagccaatgg tttagtttca caaatccttg gacaaaagaa 1500

 ctggaatata ttgtatctgt caacacttta gttttgggac atagtgagcc 1550

 tggagaagca tcatttttac cttgtagctc tcaatcatca gaagaatcct 1600

 ctagacagtc ctgtatgagt gtacctggaa tgtctactgg aacagtactt 1650

 ggtgctggta gtattggaac agatattgca aatgaaattc tggatttaca 1700

 gaggttacag tcttcttcat accttgatga ttcgagtcca acaggtttaa 1750

 tgaaagatac tcatactgta aactgcagga gtatgtcaaa taaggagttg 1800

 tttccaccaa gtccttctga aatgggggag ctagaggcta ccaggcaaaa 1850

 ccagagtact gttgctgtcc acagccatga gccactcctc agtgatggtg 1900

 cacagttgga tttcgatgcc ctatgtgaca atgatgacac agccatggct 1950

 gcatttatga attacttaga agcagagggg ggcctgggag accctgggga 2000

 cttcagtgac atccagtgga ccctctagcc tttgattttt aactccaaaa 2050

 atgagaaaca ttttaaagca ttatttacga aaaaactgtc tcaactattc 2100

 ttaagtactg tattgatatt gtttgtatct tttattaatg ttctaccact 2150

 ttttatagat ttgcatcttc ctgtcacagg gatgtgggga aatacgtttt 2200

 cctcccaaga gaaccaagtt tattatagac tcctttattc agtgaaatgg 2250

 cttataatcc actagttgcc atatttttgc taaaatattt ctaaccaaga 2300

 atactactta catattgttt tggctttgtt ttatttttga tgcagttttt 2350

 tttagttgag gtaatgtaat atattgatgt tttcctttgt gtctaagatt 2400

 gatttataat agtaggtttg tataatttgg aacattttcc atgccttgcg 2450

 aatttcctta attgaggata gggcttacac actttaagaa aacagtgagt 2500

 acttgaacat ttaaagggac agtgcaattt atagtcataa tcacattgaa 2550

 tactgtattt gatctttgga gacttaggca agcacagagc tgggatattt 2600

 atgctcagtt gagcacttta agatgaattt taagtgagat gatttcttgc 2650

 ttaaaactca gaaagtcaaa agagtttcag ctttccttac agaaaaggaa 2700

 ggatcttggg ccctagatct tggggattaa cctctgcata taagatttac 2750

 tcttaatagg ccagacgtgg tgctcacgcc tgtaatccca gtactttggg 2800

 aggctgagac gggcagatca cttgaggtca ggagttcaag accagcctgg 2850

 ccaatatggt gaaaccccgt ttctactaaa aatacaaaaa aaattaccca 2900

 ggcactcact cttgaggtaa ctaaccaact cccacgataa tgacagtcca 2950

 ttcatgagcg caaaggcctc atgacctaat ggcacacacc tgtaatccca 3000

 actgcttggg aggctgaggc gagaggattg cttgaacctg ggaggcagag 3050

 gttgcagtga gccgagatcg caccactgca ctccagtctg ggcaacagag 3100

 tgagacttca tctcaaaaaa agtaaaaaaa aagatttaat ataatcactg 3150

 aagatctcta ttatagatag attaggtttt tgacattgga aacatactta 3200

 gggatagatt tgtcctaaag gaaaaaagta ggcccgggca gattaaatgt 3250

 cttgtgtaaa gtcacacatt aaattcagtc acacattaaa ttcatagagt 3300

 tttaaatgtt taatgtatat aaaccagttt ctttatacac atttgggaaa 3350

 acattggtct cacagattaa atgattaact aactgaccca ggaactagtt 3400

 gtagctttct aagtaattag gcaattacag ttattgcctg taaccaaagg 3450

 taataaaaca aaatgacaag tacatgttta aaattatgag gcaatgagaa 3500

 ataatttaaa aaccaatttt ctagttataa tttaaaattt ggagagcatt 3550

 tttaacagta attaatccag aggtggctca aattgagtat aagaattaag 3600

 attatttaaa atactgcatg tctaccttct cggggatcat actttataac 3650

 actttctgct tcagtagctc ttcatagctt gccaagtatg ctcccatatt 3700

 ttctctctcg tgcctcgcaa atgaaagtca gataggctgg gaactcatgg 3750

 ggcagccctc agacttcaat gtgggcttca aatccagttt cctgttctat 3800

 atggtgctac atctttccag aaaatttccc tcagagcccc tcgccaaaac 3850

 aaagcattat tttgaccctg catgctattt ctttagctgt aggtgataga 3900

 ttagaacttc tgtcagacat gttaatgaca aacataccaa cagacaataa 3950

 ccaaagcaaa tgtttccttc aagtgtgaaa tgtgcagggg ctcgtgggca 4000

 aggatgtatt ggcacactgt cctcttgaac tgatagtgtc ccagcaatgt 4050

 tggaggttgg caccattcct ggtccgacac ttgaggacct gagagacatc 4100

 aggtttagaa tgagccaaag aaatcctaca agatggggag aattggtgtg 4150

 cagcagccta agtgttatag ttaagtctaa agaagtatga aagatcccct 4200

 gtgttctcta aattgagcag aggggcctgc ctaccaatat cactttttag 4250

 gggactgaac cattgcaggt tagacttggc ttccaaagag tctgcctaag 4300

 ccaggggtgg cagggtaggc catcatagct ggatggcctc aaaagcagat 4350

 gggggcagac ttgccctcgt gatgccagga tttgagaggc agagtttcta 4400

 gagggagacc agtgctgcct ctcacagtgg cagttttttc tctttgcaag 4450

 aggaggggct gttcaattcc atagaccagt gggcagatag ccagttgaat 4500

 actctgtgca tggtttgatc ctttattagt tcgctctaat atttttctgt 4550

 agatcctttt gtcctggact caaaatctaa tccatgcatt gtatgatacc 4600

 gtagctctcc taaggtttgt gtttccttca aaatgtttta gttttcttca 4650

 actaaatttg atttttgctg ttagaagtga catattttta tggtatacac 4700

 tatgttcctt ttttctactg cgagtcaatt ttttgaattt tcgtgagaaa 4750

 gaatatatct acaaattgca cgaaagtatc ataaaaacag tactctagag 4800

 cagcgctgtc caatagaaat ataatctgag ccacatgtat aattttattt 4850

 tcttctagcc acattaaaga agtaaaaaga tacaagtaga actaatttta 4900

 atgttttaat tcagtatatc caaaatatca tttgaacatg taattaatat 4950

 aaaattatta atgtgatatt ttacattctt ttggtaatac tagtcttcaa 5000

 aatctggtat gtatcttaca ttgatagcac atctcacttt gtactagcca 5050

 cattgcaagt gctcagtagc cacatgtggc tagtggctac tgcactggac 5100

 agcacagttc taggttccac cctaacaccc aagtcctgtg gattagaatc 5150

 ccagaatcag agctggaagt aaacatagag atcaaacctc cttttaaaaa 5200

 tgaggacgct gaggcacaga gtttaaatgg cttgcatgag gtcatacagc 5250

 taaattcagc ctcaacaggg tcttctgatt ccaggcactc ttcccactcc 5300

 actacattac tgtagtggta attcttaggg ttaaaaaaag tgtagagtag 5350

 gccgggcgca gtggctcatg cctgtaatcc cagcactttg ggaggccgaa 5400

 gtgggcggat cacgaggtca ggagatcgag accatcctgg ccaacatggt 5450

 gaaaccccgt ctctactgaa aatacaaagc aaaattagcc aggtgtggtg 5500

 gcgggcgcct gtggtcccag ctgctctgga ggctgaggca gaatggcgtg 5550

 aacccaggag gcagagatgg cagtgagcca agatcgcgcc actgcacccc 5600

 agcctgggcg acagagcgag actccatctc aaaaaaaaaa aaaaaaaaaa 5650

 aagaaaagaa aagaaaagtc tagagaacat tatattaagt ggttattatt 5700

 gaagtagacc aaagtttata ccataaggat atttttcctt aaataccatg 5750

 tttgaagaac aattatttat tgatccttga atctgtaaga tcaaataaca 5800

 agtctctatc catgttacca aatttaacct tttgaaaata ataaacttta 5850

 aaatatcaga tgtgttatta caggatgata cttggaatca agtgaaatga 5900

 gttatatggt catcactaaa tttagaaatc tattgtgaaa caaagacaaa 5950

 caggaaagta cagaatagag acttttagta aataaatgga atttaaaaga 6000

 aagtgtttat ttacagtgtc acgacagaaa aggatgtctt tgttgtcata 6050

 gtctttgagg gatctccgta aaatctgggg cacaggtaca agaaatagcc 6100

 aatatttagt tcccagacca tgtttagtag tgtccagttt cagatcatgc 6150

 tgccaagagg tatctccccc tcaggtgggt catcactgag ccctggaatt 6200

 ggagactcat acttgcccag cacaatgtta cgggcagaca ggccgacatc 6250

 tatgattagc tagaagccat aaagaaaagc tgctaagtgg ccactaggtg 6300

 ccacttttct gtttttgtaa tgctttcatt agcagatctt ttttttccaa 6350

 gctccatggg gcctatgaga ggcatttatg atttttgtgc ctacaataag 6400

 tcagcctgtc tggtgtgagt tgttttatga gaaatgcttt ccaagggagg 6450

 tctaggaaga tcctgacaca taagaacttt ggcttagaga gctttccagg 6500

 tgtagtgcca ataaaaactg acctggaaag aaaacctgcc cagcacggaa 6550

 catgctttct gaactcactt gagagtgtat ggtgtatgtc acttctcata 6600

 tattcttgag tttagatttg tcttttatac aatttttagc tcttttccag 6650

 ttcacttgtg ctcgtctgta tattggtatt tttaaatttt tgtggtaaat 6700

 aatgaaaaga gtgaaattat attttataat tactcatttg tagttttttt 6750

 ttttaattta ataaacttcc tccaaaaagt gctcccttaa aa 6792

<210> 3552
<211> 602
<212> PRT
<213> Homo sapien

<400> 3552
 Met Ala Ala Glu Glu Glu Ala Ala Ala Gly Gly Lys Val Leu Arg
   1               5                  10                  15

 Glu Glu Asn Gln Cys Ile Ala Pro Val Val Ser Ser Arg Val Ser
                  20                  25                  30

 Pro Gly Thr Arg Pro Thr Ala Met Gly Ser Phe Ser Ser His Met
                  35                  40                  45

 Thr Glu Phe Pro Arg Lys Arg Lys Gly Ser Asp Ser Asp Pro Ser
                  50                  55                  60

 Gln Val Glu Asp Gly Glu His Gln Val Lys Met Lys Ala Phe Arg
                  65                  70                  75

 Glu Ala His Ser Gln Thr Glu Lys Arg Arg Arg Asp Lys Met Asn
                  80                  85                  90

 Asn Leu Ile Glu Glu Leu Ser Ala Met Ile Pro Gln Cys Asn Pro
                  95                 100                 105

 Met Ala Arg Lys Leu Asp Lys Leu Thr Val Leu Arg Met Ala Val
                 110                 115                 120

 Gln His Leu Arg Ser Leu Lys Gly Leu Thr Asn Ser Tyr Val Gly
                 125                 130                 135

 Ser Asn Tyr Arg Pro Ser Phe Leu Gln Asp Asn Glu Leu Arg His
                 140                 145                 150

 Leu Ile Leu Lys Thr Ala Glu Gly Phe Leu Phe Val Val Gly Cys
                 155                 160                 165

 Glu Arg Gly Lys Ile Leu Phe Val Ser Lys Ser Val Ser Lys Ile
                 170                 175                 180

 Leu Asn Tyr Asp Gln Ala Ser Leu Thr Gly Gln Ser Leu Phe Asp
                 185                 190                 195

 Phe Leu His Pro Lys Asp Val Ala Lys Val Lys Glu Gln Leu Ser
                 200                 205                 210

 Ser Phe Asp Ile Ser Pro Arg Glu Lys Leu Ile Asp Ala Lys Thr
                 215                 220                 225

 Gly Leu Gln Val His Ser Asn Leu His Ala Gly Arg Thr Arg Val
                 230                 235                 240

 Tyr Ser Gly Ser Arg Arg Ser Phe Phe Cys Arg Ile Lys Ser Cys
                 245                 250                 255

 Lys Ile Ser Val Lys Glu Glu His Gly Cys Leu Pro Asn Ser Lys
                 260                 265                 270

 Lys Lys Glu His Arg Lys Phe Tyr Thr Ile His Cys Thr Gly Tyr
                 275                 280                 285

 Leu Arg Ser Trp Pro Pro Asn Ile Val Gly Met Glu Glu Glu Arg
                 290                 295                 300

 Asn Ser Lys Lys Asp Asn Ser Asn Phe Thr Cys Leu Val Ala Ile
                 305                 310                 315

 Gly Arg Leu Gln Pro Tyr Ile Val Pro Gln Asn Ser Gly Glu Ile
                 320                 325                 330

 Asn Val Lys Pro Thr Glu Phe Ile Thr Arg Phe Ala Val Asn Gly
                 335                 340                 345

 Lys Phe Val Tyr Val Asp Gln Arg Ala Thr Ala Ile Leu Gly Tyr
                 350                 355                 360

 Leu Pro Gln Glu Leu Leu Gly Thr Ser Cys Tyr Glu Tyr Phe His
                 365                 370                 375

 Gln Asp Asp His Asn Asn Leu Thr Asp Lys His Lys Ala Val Leu
                 380                 385                 390

 Gln Ser Lys Glu Lys Ile Leu Thr Asp Ser Tyr Lys Phe Arg Ala
                 395                 400                 405

 Lys Asp Gly Ser Phe Val Thr Leu Lys Ser Gln Trp Phe Ser Phe
                 410                 415                 420

 Thr Asn Pro Trp Thr Lys Glu Leu Glu Tyr Ile Val Ser Val Asn
                 425                 430                 435

 Thr Leu Val Leu Gly His Ser Glu Pro Gly Glu Ala Ser Phe Leu
                 440                 445                 450

 Pro Cys Ser Ser Gln Ser Ser Glu Glu Ser Ser Arg Gln Ser Cys
                 455                 460                 465

 Met Ser Val Pro Gly Met Ser Thr Gly Thr Val Leu Gly Ala Gly
                 470                 475                 480

 Ser Ile Gly Thr Asp Ile Ala Asn Glu Ile Leu Asp Leu Gln Arg
                 485                 490                 495

 Leu Gln Ser Ser Ser Tyr Leu Asp Asp Ser Ser Pro Thr Gly Leu
                 500                 505                 510

 Met Lys Asp Thr His Thr Val Asn Cys Arg Ser Met Ser Asn Lys
                 515                 520                 525

 Glu Leu Phe Pro Pro Ser Pro Ser Glu Met Gly Glu Leu Glu Ala
                 530                 535                 540

 Thr Arg Gln Asn Gln Ser Thr Val Ala Val His Ser His Glu Pro
                 545                 550                 555

 Leu Leu Ser Asp Gly Ala Gln Leu Asp Phe Asp Ala Leu Cys Asp
                 560                 565                 570

 Asn Asp Asp Thr Ala Met Ala Ala Phe Met Asn Tyr Leu Glu Ala
                 575                 580                 585

 Glu Gly Gly Leu Gly Asp Pro Gly Asp Phe Ser Asp Ile Gln Trp
                 590                 595                 600

 Thr Leu


<210> 3553
<211> 2589
<212> DNA
<213> Homo sapien

<400> 3553
 cggcccgctg gagaggaagc ccgagagctg ccgcgcgcct gccggacgag 50

 ggcgtagaag ccaggcgtca gagcccgggc tccggtgggg tcccccaccc 100

 ggccctcggg tcccccgccc cctgctccct gcccatccca gcccacgcga 150

 ccctctcgcg cgcggagggg cgggtcctcg acggctacgg gaaggtgcca 200

 gcccgccccg gatgggcatc gtggagccgg gttgcggaga catgctgacg 250

 ggcaccgagc cgatgccggg gagcgacgag ggccgggcgc ctggcgccga 300

 cccgcagcac cgctacttct acccggagcc gggcgcgcag gacgcggacg 350

 agcgtcgcgg gggcggcagc ctggggtctc cctacccggg gggcgccttg 400

 gtgcccgccc cgccgagccg cttccttgga gcctacgcct acccgccgcg 450

 accccaggcg gccggcttcc ccggcgcggg cgagtccttc ccgccgcccg 500

 cggacgccga gggctaccag ccgggcgagg gctacgccgc cccggacccg 550

 cgcgccgggc tctacccggg gccgcgtgag gactacgcgc tacccgcggg 600

 actggaggtg tcggggaaac tgagggtcgc gctcaacaac cacctgttgt 650

 ggtccaagtt taatcagcac cagacagaga tgatcatcac caagcaggga 700

 cggcggatgt tcccattcct gtcatttact gtggccgggc tggagcccac 750

 cagccactac aggatgtttg tggacgtggt cttggtggac cagcaccact 800

 ggcggtacca gagcggcaag tgggtgcagt gtggaaaggc cgagggcagc 850

 atgccaggaa accgcctgta cgtccacccg gactccccca acacaggagc 900

 gcactggatg cgccaggaag tttcatttgg gaaactaaag ctcacaaaca 950

 acaagggggc gtccaacaat gtgacccaga tgattgtgct ccagtccctc 1000

 cataagtacc agccccggct gcatatcgtt gaggtgaacg acggagagcc 1050

 agaggcagcc tgcaacgctt ccaacacgca tatctttact ttccaagaaa 1100

 cccagttcat tgccgtgact gcctaccaga atgccgagat tactcagctg 1150

 aaaattgata ataacccctt tgccaaagga ttccgggaga actttgagtc 1200

 catgtacaca tctgttgaca ccagcatccc ctccccgcct ggacccaact 1250

 gtcaattcct tgggggagat cactactctc ctctcctacc caaccagtat 1300

 cctgttccca gccgcttcta ccccgacctt cctggccagg cgaaggatgt 1350

 ggttccccag gcttactggc tgggggcccc ccgggaccac agctatgagg 1400

 ctgagtttcg agcagtcagc atgaagcctg cattcttgcc ctctgcccct 1450

 gggcccacca tgtcctacta ccgaggccag gaggtcctgg cacctggagc 1500

 tggctggcct gtggcacccc agtaccctcc caagatgggc ccggccagct 1550

 ggttccgccc tatgcggact ctgcccatgg aacccggccc tggaggctca 1600

 gagggacggg gaccagagga ccagggtccc cccttggtgt ggactgagat 1650

 tgcccccatc cggccggaat ccagtgattc aggactgggc gaaggagact 1700

 ctaagaggag gcgcgtgtcc ccctatcctt ccagtggtga cagctcctcc 1750

 cctgctgggg ccccttctcc ttttgataag gaagctgaag gacagtttta 1800

 taactatttt cccaactgag cagatgacat gatgaaagga acagaaacag 1850

 tgttattagg ttggaggaca ccgactaatt tgggaaacgg atgaaggact 1900

 gagaaggccc ccgctccctc tggcccttct ctgtttagta gttggttggg 1950

 gaagtggggc tcaagaagga ttttggggtt caccagatgc ttcctggccc 2000

 acgatgaaac ctgagagggg tgtccccttg ccccatcctc tgccctaact 2050

 acagtcgttt acctggtgct gcgtcttgct tttggtttcc agctggagaa 2100

 aagaagacaa gaaagtcttg ggcatgaagg agctttttgc atctagtggg 2150

 tgggaggggt caggtgtggg acatgggagc aggagactcc actttcttcc 2200

 tttgtacagt aactttcaac cttttcgttg gcatgtgtgt taatccctga 2250

 tccaaaaaga acaaatacac gtatgttata accatcagcc cgccagggtc 2300

 agggaaagga ctcacctgac tttggacagc tggcctgggc tccccctgct 2350

 caaacacagt ggggatcaga gaaaaggggc tggaaagggg ggaatggccc 2400

 acatctcaag aagcaagata ttgtttgtgg tggttgtgtg tgggtgtgtg 2450

 ttttttcttt ttctttcttt ttattttttt tgaatggggg aggctattta 2500

 ttgtactgag agtggtgtct ggatatattc cttttgtctt catcactttc 2550

 tgaaaataaa cataaaactg ttaaaaaaaa aaaaaaaaa 2589

<210> 3554
<211> 535
<212> PRT
<213> Homo sapien

<400> 3554
 Met Gly Ile Val Glu Pro Gly Cys Gly Asp Met Leu Thr Gly Thr
   1               5                  10                  15

 Glu Pro Met Pro Gly Ser Asp Glu Gly Arg Ala Pro Gly Ala Asp
                  20                  25                  30

 Pro Gln His Arg Tyr Phe Tyr Pro Glu Pro Gly Ala Gln Asp Ala
                  35                  40                  45

 Asp Glu Arg Arg Gly Gly Gly Ser Leu Gly Ser Pro Tyr Pro Gly
                  50                  55                  60

 Gly Ala Leu Val Pro Ala Pro Pro Ser Arg Phe Leu Gly Ala Tyr
                  65                  70                  75

 Ala Tyr Pro Pro Arg Pro Gln Ala Ala Gly Phe Pro Gly Ala Gly
                  80                  85                  90

 Glu Ser Phe Pro Pro Pro Ala Asp Ala Glu Gly Tyr Gln Pro Gly
                  95                 100                 105

 Glu Gly Tyr Ala Ala Pro Asp Pro Arg Ala Gly Leu Tyr Pro Gly
                 110                 115                 120

 Pro Arg Glu Asp Tyr Ala Leu Pro Ala Gly Leu Glu Val Ser Gly
                 125                 130                 135

 Lys Leu Arg Val Ala Leu Asn Asn His Leu Leu Trp Ser Lys Phe
                 140                 145                 150

 Asn Gln His Gln Thr Glu Met Ile Ile Thr Lys Gln Gly Arg Arg
                 155                 160                 165

 Met Phe Pro Phe Leu Ser Phe Thr Val Ala Gly Leu Glu Pro Thr
                 170                 175                 180

 Ser His Tyr Arg Met Phe Val Asp Val Val Leu Val Asp Gln His
                 185                 190                 195

 His Trp Arg Tyr Gln Ser Gly Lys Trp Val Gln Cys Gly Lys Ala
                 200                 205                 210

 Glu Gly Ser Met Pro Gly Asn Arg Leu Tyr Val His Pro Asp Ser
                 215                 220                 225

 Pro Asn Thr Gly Ala His Trp Met Arg Gln Glu Val Ser Phe Gly
                 230                 235                 240

 Lys Leu Lys Leu Thr Asn Asn Lys Gly Ala Ser Asn Asn Val Thr
                 245                 250                 255

 Gln Met Ile Val Leu Gln Ser Leu His Lys Tyr Gln Pro Arg Leu
                 260                 265                 270

 His Ile Val Glu Val Asn Asp Gly Glu Pro Glu Ala Ala Cys Asn
                 275                 280                 285

 Ala Ser Asn Thr His Ile Phe Thr Phe Gln Glu Thr Gln Phe Ile
                 290                 295                 300

 Ala Val Thr Ala Tyr Gln Asn Ala Glu Ile Thr Gln Leu Lys Ile
                 305                 310                 315

 Asp Asn Asn Pro Phe Ala Lys Gly Phe Arg Glu Asn Phe Glu Ser
                 320                 325                 330

 Met Tyr Thr Ser Val Asp Thr Ser Ile Pro Ser Pro Pro Gly Pro
                 335                 340                 345

 Asn Cys Gln Phe Leu Gly Gly Asp His Tyr Ser Pro Leu Leu Pro
                 350                 355                 360

 Asn Gln Tyr Pro Val Pro Ser Arg Phe Tyr Pro Asp Leu Pro Gly
                 365                 370                 375

 Gln Ala Lys Asp Val Val Pro Gln Ala Tyr Trp Leu Gly Ala Pro
                 380                 385                 390

 Arg Asp His Ser Tyr Glu Ala Glu Phe Arg Ala Val Ser Met Lys
                 395                 400                 405

 Pro Ala Phe Leu Pro Ser Ala Pro Gly Pro Thr Met Ser Tyr Tyr
                 410                 415                 420

 Arg Gly Gln Glu Val Leu Ala Pro Gly Ala Gly Trp Pro Val Ala
                 425                 430                 435

 Pro Gln Tyr Pro Pro Lys Met Gly Pro Ala Ser Trp Phe Arg Pro
                 440                 445                 450

 Met Arg Thr Leu Pro Met Glu Pro Gly Pro Gly Gly Ser Glu Gly
                 455                 460                 465

 Arg Gly Pro Glu Asp Gln Gly Pro Pro Leu Val Trp Thr Glu Ile
                 470                 475                 480

 Ala Pro Ile Arg Pro Glu Ser Ser Asp Ser Gly Leu Gly Glu Gly
                 485                 490                 495

 Asp Ser Lys Arg Arg Arg Val Ser Pro Tyr Pro Ser Ser Gly Asp
                 500                 505                 510

 Ser Ser Ser Pro Ala Gly Ala Pro Ser Pro Phe Asp Lys Glu Ala
                 515                 520                 525

 Glu Gly Gln Phe Tyr Asn Tyr Phe Pro Asn
                 530                 535

<210> 3555
<211> 1185
<212> DNA
<213> Homo sapien

<400> 3555
 accgtcttcc gccgcacgtg gattcagcgc gatgcccaaa tccaagcgcg 50

 acaagaaagt ctccttaacc aaaactgcca agaaaggctt ggaattgaaa 100

 caaaacctga tagaagagct tcggaaatgt gtggacacct acaagtacct 150

 tttcatcttc tctgtggcca acatgaggaa cagcaagctg aaggacatcc 200

 ggaacgcctg gaagcacagc cggatgttct ttggcaaaaa caaggtgatg 250

 atggtggcct tgggtcggag cccatctgat gaatacaaag acaacctgca 300

 ccaggtcagc aaaaggttga ggggtgaggt gggtctcctg ttcaccaacc 350

 gcacaaagga agaggtgaat gagtggttca cgaaatacac agaaatggac 400

 tacgcccgag ctggtaacaa agcagctttc actgtgagcc tggatccagg 450

 gcccctggag cagttccccc actccatgga gccacagctc aggcagctgg 500

 gcctgcccac cgccctcaag agaggtgtgg tgactctgct gtctgactac 550

 gaggtgtgca aggagggcga tgtgctgacc ccagagcagg ctcgcgtcct 600

 gaagcttttt gggtatgaga tggctgaatt caaggtgacc atcaaataca 650

 tgtgggattc acagtcggga aggttccagc agatgggaga cgacttgcca 700

 gagagcgcat ctgagtccac agaagagtca gactcagaag atgatgactg 750

 aaagggactc gggactgaag gtctcctgga agcttctggg tctcactgga 800

 ccatcaggac tgctgccgcc cctctggaga gagcagcttt ttatttgtct 850

 gtagacaggg aacatgatgg gcactgacct cctgtaaaga ataaaactgt 900

 gggccgggcg cggtggctca cgcctggaat cccagcactt tgggaagccg 950

 aggtgggcag atcataaggt caggagatta agaccatcct ggctaacacg 1000

 gtgaaacccc gtctctacta aaaatagaaa aaaaaactag ttgggcatag 1050

 tggcatgtgc ctgtagtccc agctactcag gaggctgagg caggagaatc 1100

 acttgaaccc gggaggtgga ggttgccgtg agttgagatt ggaccactgc 1150

 tctccagcct gggcaacaga gtaaaactct gtccc 1185

<210> 3556
<211> 239
<212> PRT
<213> Homo sapien

<400> 3556
 Met Pro Lys Ser Lys Arg Asp Lys Lys Val Ser Leu Thr Lys Thr
   1               5                  10                  15

 Ala Lys Lys Gly Leu Glu Leu Lys Gln Asn Leu Ile Glu Glu Leu
                  20                  25                  30

 Arg Lys Cys Val Asp Thr Tyr Lys Tyr Leu Phe Ile Phe Ser Val
                  35                  40                  45

 Ala Asn Met Arg Asn Ser Lys Leu Lys Asp Ile Arg Asn Ala Trp
                  50                  55                  60

 Lys His Ser Arg Met Phe Phe Gly Lys Asn Lys Val Met Met Val
                  65                  70                  75

 Ala Leu Gly Arg Ser Pro Ser Asp Glu Tyr Lys Asp Asn Leu His
                  80                  85                  90

 Gln Val Ser Lys Arg Leu Arg Gly Glu Val Gly Leu Leu Phe Thr
                  95                 100                 105

 Asn Arg Thr Lys Glu Glu Val Asn Glu Trp Phe Thr Lys Tyr Thr
                 110                 115                 120

 Glu Met Asp Tyr Ala Arg Ala Gly Asn Lys Ala Ala Phe Thr Val
                 125                 130                 135

 Ser Leu Asp Pro Gly Pro Leu Glu Gln Phe Pro His Ser Met Glu
                 140                 145                 150

 Pro Gln Leu Arg Gln Leu Gly Leu Pro Thr Ala Leu Lys Arg Gly
                 155                 160                 165

 Val Val Thr Leu Leu Ser Asp Tyr Glu Val Cys Lys Glu Gly Asp
                 170                 175                 180

 Val Leu Thr Pro Glu Gln Ala Arg Val Leu Lys Leu Phe Gly Tyr
                 185                 190                 195

 Glu Met Ala Glu Phe Lys Val Thr Ile Lys Tyr Met Trp Asp Ser
                 200                 205                 210

 Gln Ser Gly Arg Phe Gln Gln Met Gly Asp Asp Leu Pro Glu Ser
                 215                 220                 225

 Ala Ser Glu Ser Thr Glu Glu Ser Asp Ser Glu Asp Asp Asp
                 230                 235

<210> 3557
<211> 1330
<212> DNA
<213> Homo sapien

<400> 3557
 tttttttttt cctgtgtcag caagatcagt cttcatgaaa tcctgctaaa 50

 ttccctgtga aatataataa gcttaagaca ttttagagaa ccaaatgctg 100

 tttatgatac agtttagtag agttgtaata tatttcagca cagaatttta 150

 gaatactatg ggggctgatt ttcaattttg taagagaaat tatgagcata 200

 gtttatatag tcttttattt gtaattgttt acgtgatttc agaagtaata 250

 tgcttaagtt attctaatgt ttttaaagct agagagtctg aaaagaggga 300

 agaagaaaga aaagtgttta aattgatctc ttttgaattt aaaatgcata 350

 ttaagtataa ctagaacata aaatgaagaa tttaaattct catcttattc 400

 ctagaattat acctataata tgtatcatta cttataacaa ttcatatttt 450

 aattttgcat ggcacataat ctcttctgtg agttggattt ttaggtggtg 500

 ggaatttaag cataaattct cataactttc ttggggtcaa tttaatatta 550

 ataagtgtag taagtaataa tacccagctt gagacctcat gtacttgttg 600

 catttggatt taaagctcat ttcctataga agagctgtag aaatcagtca 650

 tgtagtttca taaactcctt catgcttgtt aataattttc aagaatctta 700

 aaataaatta caggaatatt gttatgaagt agtagaagca gtatggtata 750

 ggggagaaag tgattgtagt tgggatctga ggatagtctt tactttgcta 800

 ttaactagct gtgtgacctt gggcaagttg cttatctctg cttcagttcc 850

 ataaactaag aattacagag ctgaaccgga tcttggaagc aatctagtac 900

 aaacctctca ttttacagat gaggaagcag ataatttgca caggctttca 950

 ctgtaagaca gttgggccca aaattcagtt ttctgactct caggttggtt 1000

 ttttttttcc attatacttt acagcctctt ttcatctgta aaatgagagc 1050

 attggattag aggctctcaa aggtctcttc cagctcaaaa atattgtcat 1100

 tcctgtgaca ttagtcgtaa tataatttat taggggaaag tttgtagctt 1150

 ttatttattg gtgaaagaaa tgtttcttga agaggcagta taacctttgc 1200

 aaggttatat tttgtttttt taagagaata tcatcaggcg aggtgctatg 1250

 tctcaggcct gtaatcccag ctttgggaga ccaaggcaag aggattgctt 1300

 gagtccagga gtttgagact agcctgatcc 1330

<210> 3558
<211> 68
<212> PRT
<213> Homo sapien

<400> 3558
 Met Gly Ala Asp Phe Gln Phe Cys Lys Arg Asn Tyr Glu His Ser
   1               5                  10                  15

 Leu Tyr Ser Leu Leu Phe Val Ile Val Tyr Val Ile Ser Glu Val
                  20                  25                  30

 Ile Cys Leu Ser Tyr Ser Asn Val Phe Lys Ala Arg Glu Ser Glu
                  35                  40                  45

 Lys Arg Glu Glu Glu Arg Lys Val Phe Lys Leu Ile Ser Phe Glu
                  50                  55                  60

 Phe Lys Met His Ile Lys Tyr Asn
                  65

<210> 3559
<211> 2000
<212> DNA
<213> Homo sapien

<400> 3559
 acaaaagata ggaagaacct taaaaatata gatgcctttt atgcagtgat 50

 aaaatgtcta gatatttata ctgtggtgat tattaggaat atgtgcaaag 100

 attggctatt aggatgttca ttacagtgtt gtttaataat tataaaagga 150

 cagaaagcaa tgtggactca aaaataggaa aagaatttaa ataaatccta 200

 gtgtacccgt tatacatgaa attatggaaa tatgaccctg agcatggaaa 250

 tatgtacatg agaatgtcta aaagctagtt cattttgaaa aacaaaataa 300

 tgtcacctca tattatttat agtatataaa gatgatttta agagtggcag 350

 tgtctgggat tataggtgat tgtatttctt cccttttgca catctatgtt 400

 ctctcatttg tattgtgtgg ggagaagtga ctttttttat aaaaagaaaa 450

 aggtatatgc atcccagcag agaagcactg gctccaccca gtacctgcct 500

 cctcatgcca ccctctcaag ccaaaagccg ggggaagccc aggcaccttg 550

 accatgaccg cccgagactc acacttcttc tttctcatca gggaaggaaa 600

 gcccccctgt aagcgatact ccagatgagg gcgatgagcc catgccgatc 650

 cccgaggacc tctccaccac ctcgggagga cagcaaagct ccaagagtga 700

 cagagtcgtg ggtaagtggg tcaccagcgg cctctgtgcc tgtgaaacct 750

 ttatctcttt gtatttttcc aagacagtga tgaagggatg caagtcattt 800

 tatccattgt gttccctcaa ctggcatatt aaagaaatat ggcacaaaga 850

 tcagcaggat gggggtcctc tggtgtgtgg gaggatggac actcacaggc 900

 cagcatggcc gtgagagcca cacaccccgc aaaatgtcca agttgaggag 950

 caatcctgcc cagggacgcg tctctgtcac tgtcctctgt cctcactgca 1000

 cttgcaggaa tatcaaatgt tatggattgt agatcgtgaa aattacacac 1050

 ttacgtgttt tggcaacagt gcttttcagt gtttggggtt agaacaagcc 1100

 acatctggcc attttatgtt atccctctaa tctctagttc ttaaatttca 1150

 gatttaactg aaaatagaaa gtttcataaa tggtaatttt taaatgttag 1200

 aaaaaaatca aagcacacat ttacatacct tttccataaa aaagtgtgtg 1250

 tgaaaccatc tgcaactcca ctggttaact tacacatgcg acagtttgtg 1300

 tttggaaaac ttcacccacc ctctttattt caagaaacca aagacggaga 1350

 gaagttcagt gaattaacca aggtgaaatg acagagtcag aattgaactg 1400

 aatttctgac tgaaaaacta gttctcgctc cattatacca tgttctaatg 1450

 agctaatgag tcaacagttc cctggaatac ctgttttctt ctttaaaaag 1500

 agaaagagct gtgatactga gagctaccta ttggcataaa agaatatgaa 1550

 ggacatacag gtaaaatgag gtagactgga tcaatgtggg tcagctacat 1600

 aagcccccat agccaaggag ggaacatgta tgtaaaattc tcaggcttat 1650

 gagaatcaca actgtatgtc tataggacat cctaatgcaa taatgggaaa 1700

 atgtgataac tgaattttat ctacatgtat agaaaacata ttttgggccg 1750

 ggcatggtgg ctcaagcttg taatcccagc actttgggag gccgaggctg 1800

 gcggatcaca aggtcaggaa atcgagacca tcctggctaa cacggtgaaa 1850

 ccctgtctct actaaaaata caaaaaatta gccgggcgta gtggtgggcg 1900

 cctgtagtcc cagctactcg ggaggctgag gcaggagaat ggcgtgaacc 1950

 cggcaggcgg agcttgcagt gagccgagat tgcgccactg cactccagcc 2000

<210> 3560
<211> 90
<212> PRT
<213> Homo sapien

<400> 3560
 Met Pro Ile Pro Glu Asp Leu Ser Thr Thr Ser Gly Gly Gln Gln
   1               5                  10                  15

 Ser Ser Lys Ser Asp Arg Val Val Gly Lys Trp Val Thr Ser Gly
                  20                  25                  30

 Leu Cys Ala Cys Glu Thr Phe Ile Ser Leu Tyr Phe Ser Lys Thr
                  35                  40                  45

 Val Met Lys Gly Cys Lys Ser Phe Tyr Pro Leu Cys Ser Leu Asn
                  50                  55                  60

 Trp His Ile Lys Glu Ile Trp His Lys Asp Gln Gln Asp Gly Gly
                  65                  70                  75

 Pro Leu Val Cys Gly Arg Met Asp Thr His Arg Pro Ala Trp Pro
                  80                  85                  90

<210> 3561
<211> 4826
<212> DNA
<213> Homo sapien

<400> 3561
 gggtcgaggt cgacggtatc gataagtttt tttttttttt tttttttttt 50

 ttttcctttc ccctccccct ccctctccaa gccggagggg tcctgaggtg 100

 acagcgcctg caactgaaat ttcagcagcg ggagaagatg gacaagagaa 150

 agctcgggcg acggccatct tcatccgaaa tcatcacaga aggaaaaagg 200

 aaaaagtcat cttctgattt atcggagata agaaagatgt taaatgcaaa 250

 accagaggat gtccatgttc aatcaccact gtccaaattc agaagctcag 300

 aacgctggac tctccctttg cagtgggaaa gaagcctaag gaataaagtc 350

 atctctctag accataaaaa taaaaaacat atccgagggt gtcctgttac 400

 ttccaggtca tcaccagaaa ggatacccag agttatattg acgaatgtcc 450

 tgggaacgga gttaggaaga aaatacataa ggaccccacc tgtaactgag 500

 ggaagtttga gtgatacaga caacttgcaa tcagagcaac tttcttcatc 550

 atctgatggc agcctagaat cttatcaaaa tctaaaccct cacaagagct 600

 gttatttatc tgaaaggggc tcacaacgaa gtaagacagt agatgacaat 650

 tctgcaaagc agactgcgca caataaagaa aaacgaagaa aggatgatgg 700

 catttctctt ttaatatctg atactcagcc tgaagacctt aacagtggaa 750

 gtagaggttg tgatcatctc gaacaggaaa gcagaaacaa ggatgttaaa 800

 tattctgatt caaaagtgga actcactctg atttccagga agacaaagag 850

 aaggcttaga aataatttac ctgattctca atattgtact tctttggata 900

 agtcaacaga acagacaaaa aaacaagaag atgactcaac aatatccact 950

 gagtttgaaa ggccaagtga aaactatcat caggatccaa aactgcctga 1000

 agaaattaca actaaaccta caaaaagtga ttttactaag ctatcctcac 1050

 ttaacagtca ggagttgact ttgagtaatg ccaccaaaag tgcctctgcc 1100

 ggttcaacca ctgaaaccgt tgagtactct aattccattg atattgtggg 1150

 gatttcttcc ctggttgaga aggatgagaa tgagttgaat accatagaaa 1200

 agcctattct aagaggacat aatgaaggga accaatcact gatctcagct 1250

 gaaccaattg ttgtttccag tgatgaagaa ggacctgttg aacataaaag 1300

 ttcagaaatt cttaagttac aatctaagca agaccgtgag acaactaatg 1350

 aaaatgagag tacttctgaa tcagcattgt tagaactacc attgattaca 1400

 tgtgaatctg tacagatgtc atctgaatta tgcccatata atcctgtcat 1450

 ggagaacatt tccagtatta tgcctagtaa tgagatggat ctacaactgg 1500

 attttatatt tacttctgtt tatattggta aaataaaagg agcttctaaa 1550

 ggttgtgtta caatcacaaa aaaatatatt aagatcccat ttcaagtgtc 1600

 cctgaatgag atttcattgc tagtggatac cacacattta aagcggtttg 1650

 ggttatggaa aagtaaggat gataatcaca gtaaaaggag tcatgctatt 1700

 cttttcttct gggtctcttc agattatctt caagagattc agacccaatt 1750

 agaacactct gtattaagcc agcaatcaaa atctagtgaa ttcattttcc 1800

 ttgaactaca caatcctgtt tcacagagag aagaattgaa gctgaaagat 1850

 attatgacgg aaataagtat aatcagtgga gaattagagc tttcttaccc 1900

 gttgtcttgg gttcaggcat ttcctttgtt tcagaacctc tcttcaaaag 1950

 aaagttcttt tattcattat tactgtgttt caacttgttc tttccctgct 2000

 ggtgttgctg ttgctgaaga aatgaagctg aaatcagtat ctcagccctc 2050

 aaacacagat gcggccaagc ctacttacac cttcctgcag aagcaaagta 2100

 gcggttgcta ctccctttct attacatcta atccagatga agaatggcgg 2150

 gaagtcaggc acactggact tgttcagaag ttgattgtat atcctccacc 2200

 acctactaag gggggattgg gagtaactaa tgaagatctg gagtgtttag 2250

 aagaaggaga gtttcttaat gatgtaatca ttgattttta ccttaagtat 2300

 cttatattgg agaaggcatc agatgaactt gttgaacgaa gtcacatttt 2350

 tagtagcttt ttctataaat gcttgacaag aaaggaaaat aatttaacag 2400

 aagataatcc aaatctttca atggcacaga gaagacataa aagagtaaga 2450

 acatggactc gtcacataaa catttttaat aaagattaca tctttgtacc 2500

 tgtaaatgag tcgtctcact ggtatctcgc agtcatttgt tttccatggt 2550

 tagaagaagc tgtgtatgaa gattttccac aaactgtatc ccagcagtcc 2600

 caggctcagc agtcccaaag tgacaacaaa acaatagata atgatctacg 2650

 tactacttcg acactgtctt tgagtgcaga ggattcccaa agtaccgagt 2700

 cgaatatgtc agtaccaaag aaaatgtgta aaaggccatg tattcttata 2750

 ctagactcct tgaaagctgc ttctgtacga aacacagttc agaatttacg 2800

 agagtattta gaggtagagt gggaagttaa actaaaaact catcgtcaat 2850

 tcagcaaaac aaacatggtg gatctatgcc ctaaagttcc taaacaggac 2900

 aatagcagtg attgtggagt atatttattg cagtatgtgg aaagcttctt 2950

 caaggatcct attgttaact ttgaacttcc aattcatttg gagaagtggt 3000

 ttcctcgtca tgtaataaag accaaacggg aagatattcg agagctcatc 3050

 ttgaaacttc atttacagca acagaagggc agcagtagct agttaatctg 3100

 tacaaacatg acacagatgt tctctaagat tactggaaag ccccttacca 3150

 gcatttgtgt tagccagctc acagagaaga aaataacttg cagtagtttt 3200

 ataataagtc attggaacat tatttaaaat atgtaggaca cattattaga 3250

 attgttggga tctcatagat ggaatgggaa tgggggtgat atagataaac 3300

 ttactagata taaattaaaa ttttataaat atttcatatt tttctgagta 3350

 aatatgattg gattatgcaa cagcatatgt aatatgggaa tgttttgtag 3400

 ataataaaac ttacatgatc tgtacttcca cgtgactggg tgctgagggg 3450

 agttaaagcc tccctggtgc cagccccagt gcttgtcaaa tttgctgaca 3500

 ggtcacatca tattgtaatt ctattctttg cagctcaagc atgcagtatg 3550

 aatactgtgt attttttaaa aaaataattt agtatcaagg cttcagaaaa 3600

 tgccatttac ggcatccctt ctgtatgtaa caaaaagaca ttcataatgt 3650

 taggaagatg ataaaaattc gctcttttaa agtgcagctt attattctca 3700

 attgctaaat acgattactc tgcttttttt ttttcatttc ttttgatgtc 3750

 atatgtgagt atcttataat ttagttcatt tgttcagggt aaaatttgaa 3800

 acaaaaaatt ttacctgtgc aaaatagttt tttaaaaatt atacatgtag 3850

 ctcaacttga ggtactgcta tataaatatt cactcacatt atcacggaat 3900

 ttatgtatag tttctctaat atagaagata aaattggtgt cctcataact 3950

 ttaacaaaga aaaccctcag tcctatttat taatgggtag aattaaatat 4000

 ataattttat agctcagttt acccagtatt catctgcaaa gccagattgc 4050

 tctcattgct tttatatttt taaattgtag cttttagaga cctatgatcc 4100

 tcatggaact taatttttta ttaaatattc aggtaacagt tctgaattca 4150

 tgtgataatg gtggcattat atatgattaa acacttcaga actttctaat 4200

 gttatcagga gtattttgag ggagatatga ttatattgta ttttctcaga 4250

 taagaaaaat gttttttaac aatattattt taatctgttt taagcatctc 4300

 ttagatttac attataacta cataaagcag tgaagcaaag gcaaattaag 4350

 ataaagctag aaagtctgaa cattttattt caaaatcata cgaatcgggg 4400

 tcagttaagc ctcagtattc ttagcttttg ttgattttgg cactatcttt 4450

 atattattaa atatatttgt tgtttggata tttcatataa agatggctat 4500

 aattacatat ttcattccca atttgtgtgt gttggggggt acttttaaag 4550

 gtgactattg ttttgtacat ctaattttgg gaaaccaagt ctataagaca 4600

 tcttgtgatt tcttaatgtt tttgtttgta tgtttttcaa agatatcact 4650

 gtcctttatc atgttttgaa gattgtttaa aattcatttt cctaaattaa 4700

 tgtgcaagta atgttttgag gatatcggtg ttttatatta aacatatttc 4750

 caattcaaaa aaaaaaaaaa aaaaacttat cgataccgtc gacctcgatg 4800

 atgatgatga tgatgatgat gtcgac 4826

<210> 3562
<211> 984
<212> PRT
<213> Homo sapien

<400> 3562
 Met Asp Lys Arg Lys Leu Gly Arg Arg Pro Ser Ser Ser Glu Ile
   1               5                  10                  15

 Ile Thr Glu Gly Lys Arg Lys Lys Ser Ser Ser Asp Leu Ser Glu
                  20                  25                  30

 Ile Arg Lys Met Leu Asn Ala Lys Pro Glu Asp Val His Val Gln
                  35                  40                  45

 Ser Pro Leu Ser Lys Phe Arg Ser Ser Glu Arg Trp Thr Leu Pro
                  50                  55                  60

 Leu Gln Trp Glu Arg Ser Leu Arg Asn Lys Val Ile Ser Leu Asp
                  65                  70                  75

 His Lys Asn Lys Lys His Ile Arg Gly Cys Pro Val Thr Ser Arg
                  80                  85                  90

 Ser Ser Pro Glu Arg Ile Pro Arg Val Ile Leu Thr Asn Val Leu
                  95                 100                 105

 Gly Thr Glu Leu Gly Arg Lys Tyr Ile Arg Thr Pro Pro Val Thr
                 110                 115                 120

 Glu Gly Ser Leu Ser Asp Thr Asp Asn Leu Gln Ser Glu Gln Leu
                 125                 130                 135

 Ser Ser Ser Ser Asp Gly Ser Leu Glu Ser Tyr Gln Asn Leu Asn
                 140                 145                 150

 Pro His Lys Ser Cys Tyr Leu Ser Glu Arg Gly Ser Gln Arg Ser
                 155                 160                 165

 Lys Thr Val Asp Asp Asn Ser Ala Lys Gln Thr Ala His Asn Lys
                 170                 175                 180

 Glu Lys Arg Arg Lys Asp Asp Gly Ile Ser Leu Leu Ile Ser Asp
                 185                 190                 195

 Thr Gln Pro Glu Asp Leu Asn Ser Gly Ser Arg Gly Cys Asp His
                 200                 205                 210

 Leu Glu Gln Glu Ser Arg Asn Lys Asp Val Lys Tyr Ser Asp Ser
                 215                 220                 225

 Lys Val Glu Leu Thr Leu Ile Ser Arg Lys Thr Lys Arg Arg Leu
                 230                 235                 240

 Arg Asn Asn Leu Pro Asp Ser Gln Tyr Cys Thr Ser Leu Asp Lys
                 245                 250                 255

 Ser Thr Glu Gln Thr Lys Lys Gln Glu Asp Asp Ser Thr Ile Ser
                 260                 265                 270

 Thr Glu Phe Glu Arg Pro Ser Glu Asn Tyr His Gln Asp Pro Lys
                 275                 280                 285

 Leu Pro Glu Glu Ile Thr Thr Lys Pro Thr Lys Ser Asp Phe Thr
                 290                 295                 300

 Lys Leu Ser Ser Leu Asn Ser Gln Glu Leu Thr Leu Ser Asn Ala
                 305                 310                 315

 Thr Lys Ser Ala Ser Ala Gly Ser Thr Thr Glu Thr Val Glu Tyr
                 320                 325                 330

 Ser Asn Ser Ile Asp Ile Val Gly Ile Ser Ser Leu Val Glu Lys
                 335                 340                 345

 Asp Glu Asn Glu Leu Asn Thr Ile Glu Lys Pro Ile Leu Arg Gly
                 350                 355                 360

 His Asn Glu Gly Asn Gln Ser Leu Ile Ser Ala Glu Pro Ile Val
                 365                 370                 375

 Val Ser Ser Asp Glu Glu Gly Pro Val Glu His Lys Ser Ser Glu
                 380                 385                 390

 Ile Leu Lys Leu Gln Ser Lys Gln Asp Arg Glu Thr Thr Asn Glu
                 395                 400                 405

 Asn Glu Ser Thr Ser Glu Ser Ala Leu Leu Glu Leu Pro Leu Ile
                 410                 415                 420

 Thr Cys Glu Ser Val Gln Met Ser Ser Glu Leu Cys Pro Tyr Asn
                 425                 430                 435

 Pro Val Met Glu Asn Ile Ser Ser Ile Met Pro Ser Asn Glu Met
                 440                 445                 450

 Asp Leu Gln Leu Asp Phe Ile Phe Thr Ser Val Tyr Ile Gly Lys
                 455                 460                 465

 Ile Lys Gly Ala Ser Lys Gly Cys Val Thr Ile Thr Lys Lys Tyr
                 470                 475                 480

 Ile Lys Ile Pro Phe Gln Val Ser Leu Asn Glu Ile Ser Leu Leu
                 485                 490                 495

 Val Asp Thr Thr His Leu Lys Arg Phe Gly Leu Trp Lys Ser Lys
                 500                 505                 510

 Asp Asp Asn His Ser Lys Arg Ser His Ala Ile Leu Phe Phe Trp
                 515                 520                 525

 Val Ser Ser Asp Tyr Leu Gln Glu Ile Gln Thr Gln Leu Glu His
                 530                 535                 540

 Ser Val Leu Ser Gln Gln Ser Lys Ser Ser Glu Phe Ile Phe Leu
                 545                 550                 555

 Glu Leu His Asn Pro Val Ser Gln Arg Glu Glu Leu Lys Leu Lys
                 560                 565                 570

 Asp Ile Met Thr Glu Ile Ser Ile Ile Ser Gly Glu Leu Glu Leu
                 575                 580                 585

 Ser Tyr Pro Leu Ser Trp Val Gln Ala Phe Pro Leu Phe Gln Asn
                 590                 595                 600

 Leu Ser Ser Lys Glu Ser Ser Phe Ile His Tyr Tyr Cys Val Ser
                 605                 610                 615

 Thr Cys Ser Phe Pro Ala Gly Val Ala Val Ala Glu Glu Met Lys
                 620                 625                 630

 Leu Lys Ser Val Ser Gln Pro Ser Asn Thr Asp Ala Ala Lys Pro
                 635                 640                 645

 Thr Tyr Thr Phe Leu Gln Lys Gln Ser Ser Gly Cys Tyr Ser Leu
                 650                 655                 660

 Ser Ile Thr Ser Asn Pro Asp Glu Glu Trp Arg Glu Val Arg His
                 665                 670                 675

 Thr Gly Leu Val Gln Lys Leu Ile Val Tyr Pro Pro Pro Pro Thr
                 680                 685                 690

 Lys Gly Gly Leu Gly Val Thr Asn Glu Asp Leu Glu Cys Leu Glu
                 695                 700                 705

 Glu Gly Glu Phe Leu Asn Asp Val Ile Ile Asp Phe Tyr Leu Lys
                 710                 715                 720

 Tyr Leu Ile Leu Glu Lys Ala Ser Asp Glu Leu Val Glu Arg Ser
                 725                 730                 735

 His Ile Phe Ser Ser Phe Phe Tyr Lys Cys Leu Thr Arg Lys Glu
                 740                 745                 750

 Asn Asn Leu Thr Glu Asp Asn Pro Asn Leu Ser Met Ala Gln Arg
                 755                 760                 765

 Arg His Lys Arg Val Arg Thr Trp Thr Arg His Ile Asn Ile Phe
                 770                 775                 780

 Asn Lys Asp Tyr Ile Phe Val Pro Val Asn Glu Ser Ser His Trp
                 785                 790                 795

 Tyr Leu Ala Val Ile Cys Phe Pro Trp Leu Glu Glu Ala Val Tyr
                 800                 805                 810

 Glu Asp Phe Pro Gln Thr Val Ser Gln Gln Ser Gln Ala Gln Gln
                 815                 820                 825

 Ser Gln Ser Asp Asn Lys Thr Ile Asp Asn Asp Leu Arg Thr Thr
                 830                 835                 840

 Ser Thr Leu Ser Leu Ser Ala Glu Asp Ser Gln Ser Thr Glu Ser
                 845                 850                 855

 Asn Met Ser Val Pro Lys Lys Met Cys Lys Arg Pro Cys Ile Leu
                 860                 865                 870

 Ile Leu Asp Ser Leu Lys Ala Ala Ser Val Arg Asn Thr Val Gln
                 875                 880                 885

 Asn Leu Arg Glu Tyr Leu Glu Val Glu Trp Glu Val Lys Leu Lys
                 890                 895                 900

 Thr His Arg Gln Phe Ser Lys Thr Asn Met Val Asp Leu Cys Pro
                 905                 910                 915

 Lys Val Pro Lys Gln Asp Asn Ser Ser Asp Cys Gly Val Tyr Leu
                 920                 925                 930

 Leu Gln Tyr Val Glu Ser Phe Phe Lys Asp Pro Ile Val Asn Phe
                 935                 940                 945

 Glu Leu Pro Ile His Leu Glu Lys Trp Phe Pro Arg His Val Ile
                 950                 955                 960

 Lys Thr Lys Arg Glu Asp Ile Arg Glu Leu Ile Leu Lys Leu His
                 965                 970                 975

 Leu Gln Gln Gln Lys Gly Ser Ser Ser
                 980

<210> 3563
<211> 3204
<212> DNA
<213> Homo sapien

<400> 3563
 agcgggtgct gggaaacatg gcgaccgagg gaatgatcct tactaaccac 50

 gaccatcaaa tccgtgtcgg agtccttaca gtgagtgata gttgcttcag 100

 gaatcttgca gaagaccgca gtgggataaa tctcaaagat ctcgtacaag 150

 atccttcttt gttgggtggg actatatcag catacaagat agtaccagat 200

 gaaatagaag aaatcaagga aaccctgata gattggtgtg atgaaaagga 250

 acttaatttg atattaacaa ctggaggaac aggatttgca ccacgagatg 300

 tcactccaga ggccacaaaa gaagtaatag aacgggaagc accagggatg 350

 gccctggcaa tgctgatggg atcacttaat gttacacctc tgggcatgct 400

 ctctaggcct gtatgtggaa tcagagggaa aacgcttata attaacctgc 450

 caggtagcaa gaaaggatct caggaatgct ttcaattcat actgccagct 500

 ctacctcatg ccattgacct tttacgtgat gccattgtaa aagtaaagga 550

 ggtgcatgat gaacttgaag atttgccttc cccacctccc cctctttccc 600

 ctcctcctac taccagcccc cataaacaga cagaagacaa aggagttcaa 650

 tgtgaggaag aggaagaaga gaagaaagac agtggtgttg cttcaacaga 700

 agatagttcc tcatcacata taactgcagc agccattgct gccaagaagc 750

 atccattcta caccagtcct gctgttgtca tggcacacgg tgaacagccc 800

 atccctggtc tcatcaatta ttcccatcat tcaacagatg aacggattcc 850

 agactccatc atttctcgtg gtgttcaggt gctcccacga gacacagcct 900

 ccctcagcac tactccttca gaatcgcctc gtgctcaggc tacatctcgc 950

 ctctctacag cttcctgccc aacaccaaaa gtccagtcca ggtgcagcag 1000

 caaggagaac attctcagag ccagtcacag tgctgtcgat atcaccaagg 1050

 tggctagaag acatcgcatg tctccttttc ctctgacatc tatggacaaa 1100

 gcctttatca cagtcctgga gatgactccg gtgcttggga cagaaatcat 1150

 caattaccga gatggaatgg ggcgagtcct tgctcaagat gtatatgcaa 1200

 aagacaattt accccccttc ccagcatcag taaaagatgg ctatgctgtc 1250

 cgagctgctg atggcccagg agatcgtttc atcattgggg aatcccaagc 1300

 tggtgaacag ccaactcaga cagtaatgcc aggacaagtc atgcgggtta 1350

 caacaggtgc tccaataccc tgcggtgctg atgcagtagt acaagtggaa 1400

 gataccgaac ttatcaggga atcagatgat ggcactgaag aacttgaagt 1450

 gcgaattctg gtgcaagctc ggccaggcca agatatcagg cccatcggcc 1500

 atgacattaa aagaggggaa tgtgttttgg ccaaaggaac ccacatgggc 1550

 ccctcagaga ttggtcttct ggcaactgta ggtgtcacag aggttgaagt 1600

 taataagttt ccagtggttg cagtcatgtc aacagggaat gagctgctaa 1650

 atcctgaaga tgacctctta ccagggaaga ttcgagacag caatcgttca 1700

 actcttctag caacaattca ggaacatggt taccccacga tcaacttggg 1750

 tattgtagga gacaacccag atgacttact caatgccttg aatgagggta 1800

 tcagtcgtgc tgatgtcatc atcacatcag ggggtgtatc catgggggaa 1850

 aaggactatc tcaagcaggt gctggacatt gatcttcatg ctcagatcca 1900

 ttttggcagg gtttttatga aaccaggctt gccaacaaca tttgcaactt 1950

 tggatattga tggtgtaaga aaaataatct ttgcactacc tgggaatcct 2000

 gtatcggctg tggtcacctg caatctcttt gttgtgcctg cactgaggaa 2050

 aatgcagggc atcttggatc ctcggccaac catcatcaaa gcaaggttat 2100

 catgtgatgt aaaacttgat cctcgtccag aataccatcg gtgtatacta 2150

 acttggcatc accaagaacc actaccttgg gcacagagta caggtaatca 2200

 aatgagcagc cgtctgatga gcatgcgcag tgccaatgga ttgttgatgc 2250

 tacctccaaa gacagaacag tacgtggagc tccacaaagg cgaggtggtg 2300

 gatgtcatgg tcattggacg gctatgatgg tcaccagcag gagaaagctt 2350

 tgatgcatgt ccacatatca ttgactgtat cctgtaatat gcaacggcac 2400

 agctagtttt cccgatttgg ataaaagttg atctgtatag tcaacatctt 2450

 gaactatatt tcaaatgaat ttaaatatct tttaaagaaa aaaacaccta 2500

 aaaataaatc ttaacagaaa attctgttct gattatatca aggcaaattt 2550

 ttcctttctt gcaaattgct ttgtgtgttc aatgctaggt ctgatagcga 2600

 tagcttttag tagacagcgg taggtgcctg cagaacttgt gtttttctca 2650

 tctttaaaat acaactactt atgctcttaa atcaaggctg tctgcttatt 2700

 tatactagcg taggcaacac ttggatttcc cttcttagta tgcttcataa 2750

 ctgctttaca gagagctttt gcttgttctt tctcatgtat ctcgtgttta 2800

 tgtgcacagt gccaaaagaa gactgactgg gtggaggctc tgccttgcct 2850

 caagaaccat cccctgcaga gcatccaggg aggtttctcg ccccaatagc 2900

 ctcacggcac agtactcttg ggcagtaact ggacaccttt tatttgaaga 2950

 aacaaactga agaaaaaatg cttccttaag tgctgacagc ctttttaacc 3000

 aatacattta aaattgtaca gaacaaaaaa ataaaatcaa agactgatct 3050

 tgtacagata ttagtgttac cagcattcat gtggaagtca agagcaaaga 3100

 caaaataatg ttaaacaatt ctgtaccata acattttctg taatgatact 3150

 gaaacttaat gaataaaaaa attccttgat cattatttaa aaaaaaaaaa 3200

 aaaa 3204

<210> 3564
<211> 769
<212> PRT
<213> Homo sapien

<400> 3564
 Met Ala Thr Glu Gly Met Ile Leu Thr Asn His Asp His Gln Ile
   1               5                  10                  15

 Arg Val Gly Val Leu Thr Val Ser Asp Ser Cys Phe Arg Asn Leu
                  20                  25                  30

 Ala Glu Asp Arg Ser Gly Ile Asn Leu Lys Asp Leu Val Gln Asp
                  35                  40                  45

 Pro Ser Leu Leu Gly Gly Thr Ile Ser Ala Tyr Lys Ile Val Pro
                  50                  55                  60

 Asp Glu Ile Glu Glu Ile Lys Glu Thr Leu Ile Asp Trp Cys Asp
                  65                  70                  75

 Glu Lys Glu Leu Asn Leu Ile Leu Thr Thr Gly Gly Thr Gly Phe
                  80                  85                  90

 Ala Pro Arg Asp Val Thr Pro Glu Ala Thr Lys Glu Val Ile Glu
                  95                 100                 105

 Arg Glu Ala Pro Gly Met Ala Leu Ala Met Leu Met Gly Ser Leu
                 110                 115                 120

 Asn Val Thr Pro Leu Gly Met Leu Ser Arg Pro Val Cys Gly Ile
                 125                 130                 135

 Arg Gly Lys Thr Leu Ile Ile Asn Leu Pro Gly Ser Lys Lys Gly
                 140                 145                 150

 Ser Gln Glu Cys Phe Gln Phe Ile Leu Pro Ala Leu Pro His Ala
                 155                 160                 165

 Ile Asp Leu Leu Arg Asp Ala Ile Val Lys Val Lys Glu Val His
                 170                 175                 180

 Asp Glu Leu Glu Asp Leu Pro Ser Pro Pro Pro Pro Leu Ser Pro
                 185                 190                 195

 Pro Pro Thr Thr Ser Pro His Lys Gln Thr Glu Asp Lys Gly Val
                 200                 205                 210

 Gln Cys Glu Glu Glu Glu Glu Glu Lys Lys Asp Ser Gly Val Ala
                 215                 220                 225

 Ser Thr Glu Asp Ser Ser Ser Ser His Ile Thr Ala Ala Ala Ile
                 230                 235                 240

 Ala Ala Lys Lys His Pro Phe Tyr Thr Ser Pro Ala Val Val Met
                 245                 250                 255

 Ala His Gly Glu Gln Pro Ile Pro Gly Leu Ile Asn Tyr Ser His
                 260                 265                 270

 His Ser Thr Asp Glu Arg Ile Pro Asp Ser Ile Ile Ser Arg Gly
                 275                 280                 285

 Val Gln Val Leu Pro Arg Asp Thr Ala Ser Leu Ser Thr Thr Pro
                 290                 295                 300

 Ser Glu Ser Pro Arg Ala Gln Ala Thr Ser Arg Leu Ser Thr Ala
                 305                 310                 315

 Ser Cys Pro Thr Pro Lys Val Gln Ser Arg Cys Ser Ser Lys Glu
                 320                 325                 330

 Asn Ile Leu Arg Ala Ser His Ser Ala Val Asp Ile Thr Lys Val
                 335                 340                 345

 Ala Arg Arg His Arg Met Ser Pro Phe Pro Leu Thr Ser Met Asp
                 350                 355                 360

 Lys Ala Phe Ile Thr Val Leu Glu Met Thr Pro Val Leu Gly Thr
                 365                 370                 375

 Glu Ile Ile Asn Tyr Arg Asp Gly Met Gly Arg Val Leu Ala Gln
                 380                 385                 390

 Asp Val Tyr Ala Lys Asp Asn Leu Pro Pro Phe Pro Ala Ser Val
                 395                 400                 405

 Lys Asp Gly Tyr Ala Val Arg Ala Ala Asp Gly Pro Gly Asp Arg
                 410                 415                 420

 Phe Ile Ile Gly Glu Ser Gln Ala Gly Glu Gln Pro Thr Gln Thr
                 425                 430                 435

 Val Met Pro Gly Gln Val Met Arg Val Thr Thr Gly Ala Pro Ile
                 440                 445                 450

 Pro Cys Gly Ala Asp Ala Val Val Gln Val Glu Asp Thr Glu Leu
                 455                 460                 465

 Ile Arg Glu Ser Asp Asp Gly Thr Glu Glu Leu Glu Val Arg Ile
                 470                 475                 480

 Leu Val Gln Ala Arg Pro Gly Gln Asp Ile Arg Pro Ile Gly His
                 485                 490                 495

 Asp Ile Lys Arg Gly Glu Cys Val Leu Ala Lys Gly Thr His Met
                 500                 505                 510

 Gly Pro Ser Glu Ile Gly Leu Leu Ala Thr Val Gly Val Thr Glu
                 515                 520                 525

 Val Glu Val Asn Lys Phe Pro Val Val Ala Val Met Ser Thr Gly
                 530                 535                 540

 Asn Glu Leu Leu Asn Pro Glu Asp Asp Leu Leu Pro Gly Lys Ile
                 545                 550                 555

 Arg Asp Ser Asn Arg Ser Thr Leu Leu Ala Thr Ile Gln Glu His
                 560                 565                 570

 Gly Tyr Pro Thr Ile Asn Leu Gly Ile Val Gly Asp Asn Pro Asp
                 575                 580                 585

 Asp Leu Leu Asn Ala Leu Asn Glu Gly Ile Ser Arg Ala Asp Val
                 590                 595                 600

 Ile Ile Thr Ser Gly Gly Val Ser Met Gly Glu Lys Asp Tyr Leu
                 605                 610                 615

 Lys Gln Val Leu Asp Ile Asp Leu His Ala Gln Ile His Phe Gly
                 620                 625                 630

 Arg Val Phe Met Lys Pro Gly Leu Pro Thr Thr Phe Ala Thr Leu
                 635                 640                 645

 Asp Ile Asp Gly Val Arg Lys Ile Ile Phe Ala Leu Pro Gly Asn
                 650                 655                 660

 Pro Val Ser Ala Val Val Thr Cys Asn Leu Phe Val Val Pro Ala
                 665                 670                 675

 Leu Arg Lys Met Gln Gly Ile Leu Asp Pro Arg Pro Thr Ile Ile
                 680                 685                 690

 Lys Ala Arg Leu Ser Cys Asp Val Lys Leu Asp Pro Arg Pro Glu
                 695                 700                 705

 Tyr His Arg Cys Ile Leu Thr Trp His His Gln Glu Pro Leu Pro
                 710                 715                 720

 Trp Ala Gln Ser Thr Gly Asn Gln Met Ser Ser Arg Leu Met Ser
                 725                 730                 735

 Met Arg Ser Ala Asn Gly Leu Leu Met Leu Pro Pro Lys Thr Glu
                 740                 745                 750

 Gln Tyr Val Glu Leu His Lys Gly Glu Val Val Asp Val Met Val
                 755                 760                 765

 Ile Gly Arg Leu


<210> 3565
<211> 2616
<212> DNA
<213> Homo sapien

<400> 3565
 gaagagtggt gtttttttct tcttcttctt cttttgtggt ttcacatagc 50

 aaatgagtga cagtctctac ttacagacaa agtgagacgt caggcattga 100

 gacatagctc catagaattc agtttctgag aaccagccag aagcatgcag 150

 tgacattgca caatctgcct ctgaagctgg agatactagc tgcagagctc 200

 aggggagctg ctccacatca ccgacatgaa gggaacaggc atcatggact 250

 gtgcgcccaa ggcactcctg gccagggcac tttatgacaa ctgccctgac 300

 tgctctgacg agctggcttt cagcagaggg gacatcctga ccattctgga 350

 gcaacacgtg ccagaaagcg agggttggtg gaagtgtttg ctccatggga 400

 ggcaaggcct ggcccctgcc aaccgcctcc aaatcctcac ggaggtcgct 450

 gcagacaggc cgtgcccccc attcctgaga ggcctggaag aagctcctgc 500

 cagctcagag gagacctatc aggtgcccac tctaccccgc cctcccactc 550

 caggccccgt ttatgagcag atgaggagtt gggcggaggg gccccagccc 600

 cctactgccc aagtctatga attccccgac cctcccacca gtgccagaat 650

 catctgtgaa aagactctca gctttccaaa acaggccatc ctcacgcttc 700

 ccagacctgt ccgggcctca ctgccgactc tgccttccca ggtgtatgac 750

 gtgcctaccc agcaccgggg ccccgtggtc ctgaaggagc cagagaagca 800

 gcagttatat gacataccag ccagccccaa gaaggcagga ctccatcccc 850

 cagacagcca agcaagtggg cagggtgttc ccctgatatc agtgactacc 900

 ttaagaagag gcggttacag cacattacca aatcctcaga aatcggaatg 950

 gatttatgac actccagtgt ctccaggaaa ggccagcgtc agaaacacgc 1000

 ctctcaccag ctttgcggaa gaatcaaggc cccacgctct ccccagttcc 1050

 agctccactt tctacaatcc tccaagtggc agatccaggt ccctcactcc 1100

 acaactgaat aacaatgtgc ccatgcagaa aaaactcagc cttccagaaa 1150

 ttccttctta tggctttctt gtacccagag gcacatttcc tttggatgaa 1200

 gatgtcagca acaaggttcc ttcaagcttc tctgattccc cgagtggaca 1250

 gcagaacacc aagcccaata tagacatccc taaagcaacg tcgagtgttt 1300

 ctcaggctgg gaaggagctg gagaaagcca aggaggtgtc agagaattcc 1350

 gcgggccata attcctcatg gttctccaga cggacaactt ccccatctcc 1400

 tgaaccggac agattatcag gttccagttc tgacagcaga gctagcatcg 1450

 tttcctcgtg ctccaccaca tccaccgacg actcctccag ctcttcctcg 1500

 gaggagtcag caaaggagct ctccttggac ctggatgtgg ccaaggagac 1550

 agtgatggct ctgcagcaca aggtggtcag ctctgtcgct ggcctgatgc 1600

 tctttgtcag caggaagtgg agattccgag actatctgga ggccaacatt 1650

 gatgcaatcc acaggtccac tgatcacata gaagcctctg taagagaatt 1700

 tctggatttt gcccgaggag tccatgggac tgcctgtaac ctcactgaca 1750

 gtaaccttca gaacagaatt cgggaccaga tgcagaccat ctccaactcc 1800

 taccgcatcc tgcttgaaac aaaggaaagc ttggataatc gcaattggcc 1850

 tctggaagtt cttgtgactg acagtgtcca gaacagccca gatgaccttg 1900

 agaggtttgt catggtggca cggatgcttc cagaagacat caagaggttt 1950

 gcctccattg tcattgccaa tggaaggctc ctttttaagc ggaactgtga 2000

 aaaggaagag actgtgcagt tgaccccaaa tgcagaattt aagtgtgaaa 2050

 aatacatcca gcctccccaa agagaaactg aatcacacca aaagagtacc 2100

 ccttccacta agcaaaggga agatgaacac tcttctgaac tattaaagaa 2150

 aaatagagca aatatctgtg gacagaatcc tggccctctt atacctcagc 2200

 cttcgagtca acagactcct gagaggaaac cccgcttatc tgaacactgc 2250

 cggctgtact ttggggcgct cttcaaagcc atcagcgcat ttcacggcag 2300

 cctcagcagc agccagcccg cggagatcat cactcagagc aagctggtca 2350

 tcatggtggg acagaagctg gtggacacgc tgtgcatgga gacccaggag 2400

 agggacgtgc gcaatgagat cctccgcggc agcagtcacc tctgcagcct 2450

 gctcaaggac gtagcgctgg ccactaagaa tgccgtgctc acatacccca 2500

 gccctgccgc gctggggcac ctccaggcgg aggctgagaa gctggagcaa 2550

 cacacgcggc agttcagagg gacactggga tgaggactgt ctacctccct 2600

 tcctcctctg ctcacc 2616

<210> 3566
<211> 785
<212> PRT
<213> Homo sapien

<400> 3566
 Met Lys Gly Thr Gly Ile Met Asp Cys Ala Pro Lys Ala Leu Leu
   1               5                  10                  15

 Ala Arg Ala Leu Tyr Asp Asn Cys Pro Asp Cys Ser Asp Glu Leu
                  20                  25                  30

 Ala Phe Ser Arg Gly Asp Ile Leu Thr Ile Leu Glu Gln His Val
                  35                  40                  45

 Pro Glu Ser Glu Gly Trp Trp Lys Cys Leu Leu His Gly Arg Gln
                  50                  55                  60

 Gly Leu Ala Pro Ala Asn Arg Leu Gln Ile Leu Thr Glu Val Ala
                  65                  70                  75

 Ala Asp Arg Pro Cys Pro Pro Phe Leu Arg Gly Leu Glu Glu Ala
                  80                  85                  90

 Pro Ala Ser Ser Glu Glu Thr Tyr Gln Val Pro Thr Leu Pro Arg
                  95                 100                 105

 Pro Pro Thr Pro Gly Pro Val Tyr Glu Gln Met Arg Ser Trp Ala
                 110                 115                 120

 Glu Gly Pro Gln Pro Pro Thr Ala Gln Val Tyr Glu Phe Pro Asp
                 125                 130                 135

 Pro Pro Thr Ser Ala Arg Ile Ile Cys Glu Lys Thr Leu Ser Phe
                 140                 145                 150

 Pro Lys Gln Ala Ile Leu Thr Leu Pro Arg Pro Val Arg Ala Ser
                 155                 160                 165

 Leu Pro Thr Leu Pro Ser Gln Val Tyr Asp Val Pro Thr Gln His
                 170                 175                 180

 Arg Gly Pro Val Val Leu Lys Glu Pro Glu Lys Gln Gln Leu Tyr
                 185                 190                 195

 Asp Ile Pro Ala Ser Pro Lys Lys Ala Gly Leu His Pro Pro Asp
                 200                 205                 210

 Ser Gln Ala Ser Gly Gln Gly Val Pro Leu Ile Ser Val Thr Thr
                 215                 220                 225

 Leu Arg Arg Gly Gly Tyr Ser Thr Leu Pro Asn Pro Gln Lys Ser
                 230                 235                 240

 Glu Trp Ile Tyr Asp Thr Pro Val Ser Pro Gly Lys Ala Ser Val
                 245                 250                 255

 Arg Asn Thr Pro Leu Thr Ser Phe Ala Glu Glu Ser Arg Pro His
                 260                 265                 270

 Ala Leu Pro Ser Ser Ser Ser Thr Phe Tyr Asn Pro Pro Ser Gly
                 275                 280                 285

 Arg Ser Arg Ser Leu Thr Pro Gln Leu Asn Asn Asn Val Pro Met
                 290                 295                 300

 Gln Lys Lys Leu Ser Leu Pro Glu Ile Pro Ser Tyr Gly Phe Leu
                 305                 310                 315

 Val Pro Arg Gly Thr Phe Pro Leu Asp Glu Asp Val Ser Asn Lys
                 320                 325                 330

 Val Pro Ser Ser Phe Ser Asp Ser Pro Ser Gly Gln Gln Asn Thr
                 335                 340                 345

 Lys Pro Asn Ile Asp Ile Pro Lys Ala Thr Ser Ser Val Ser Gln
                 350                 355                 360

 Ala Gly Lys Glu Leu Glu Lys Ala Lys Glu Val Ser Glu Asn Ser
                 365                 370                 375

 Ala Gly His Asn Ser Ser Trp Phe Ser Arg Arg Thr Thr Ser Pro
                 380                 385                 390

 Ser Pro Glu Pro Asp Arg Leu Ser Gly Ser Ser Ser Asp Ser Arg
                 395                 400                 405

 Ala Ser Ile Val Ser Ser Cys Ser Thr Thr Ser Thr Asp Asp Ser
                 410                 415                 420

 Ser Ser Ser Ser Ser Glu Glu Ser Ala Lys Glu Leu Ser Leu Asp
                 425                 430                 435

 Leu Asp Val Ala Lys Glu Thr Val Met Ala Leu Gln His Lys Val
                 440                 445                 450

 Val Ser Ser Val Ala Gly Leu Met Leu Phe Val Ser Arg Lys Trp
                 455                 460                 465

 Arg Phe Arg Asp Tyr Leu Glu Ala Asn Ile Asp Ala Ile His Arg
                 470                 475                 480

 Ser Thr Asp His Ile Glu Ala Ser Val Arg Glu Phe Leu Asp Phe
                 485                 490                 495

 Ala Arg Gly Val His Gly Thr Ala Cys Asn Leu Thr Asp Ser Asn
                 500                 505                 510

 Leu Gln Asn Arg Ile Arg Asp Gln Met Gln Thr Ile Ser Asn Ser
                 515                 520                 525

 Tyr Arg Ile Leu Leu Glu Thr Lys Glu Ser Leu Asp Asn Arg Asn
                 530                 535                 540

 Trp Pro Leu Glu Val Leu Val Thr Asp Ser Val Gln Asn Ser Pro
                 545                 550                 555

 Asp Asp Leu Glu Arg Phe Val Met Val Ala Arg Met Leu Pro Glu
                 560                 565                 570

 Asp Ile Lys Arg Phe Ala Ser Ile Val Ile Ala Asn Gly Arg Leu
                 575                 580                 585

 Leu Phe Lys Arg Asn Cys Glu Lys Glu Glu Thr Val Gln Leu Thr
                 590                 595                 600

 Pro Asn Ala Glu Phe Lys Cys Glu Lys Tyr Ile Gln Pro Pro Gln
                 605                 610                 615

 Arg Glu Thr Glu Ser His Gln Lys Ser Thr Pro Ser Thr Lys Gln
                 620                 625                 630

 Arg Glu Asp Glu His Ser Ser Glu Leu Leu Lys Lys Asn Arg Ala
                 635                 640                 645

 Asn Ile Cys Gly Gln Asn Pro Gly Pro Leu Ile Pro Gln Pro Ser
                 650                 655                 660

 Ser Gln Gln Thr Pro Glu Arg Lys Pro Arg Leu Ser Glu His Cys
                 665                 670                 675

 Arg Leu Tyr Phe Gly Ala Leu Phe Lys Ala Ile Ser Ala Phe His
                 680                 685                 690

 Gly Ser Leu Ser Ser Ser Gln Pro Ala Glu Ile Ile Thr Gln Ser
                 695                 700                 705

 Lys Leu Val Ile Met Val Gly Gln Lys Leu Val Asp Thr Leu Cys
                 710                 715                 720

 Met Glu Thr Gln Glu Arg Asp Val Arg Asn Glu Ile Leu Arg Gly
                 725                 730                 735

 Ser Ser His Leu Cys Ser Leu Leu Lys Asp Val Ala Leu Ala Thr
                 740                 745                 750

 Lys Asn Ala Val Leu Thr Tyr Pro Ser Pro Ala Ala Leu Gly His
                 755                 760                 765

 Leu Gln Ala Glu Ala Glu Lys Leu Glu Gln His Thr Arg Gln Phe
                 770                 775                 780

 Arg Gly Thr Leu Gly
                 785

<210> 3567
<211> 2229
<212> DNA
<213> Homo sapien

<400> 3567
 ggcacgaggg ccaggaacgc cagccgttca cgcgttcggt cctccttggc 50

 tgactcaccg ccctcgccgc cgcaccatgg acgcccccag gcaggtggtc 100

 aactttgggc ctggtcccgc caagctgccg cactcagtgt tgttagagat 150

 acaaaaggaa ttattagact acaaaggagt tggcattagt gttcttgaaa 200

 tgagtcacag gtcatcagat tttgccaaga ttattaacaa tacagagaat 250

 cttgtgcggg aattgctagc tgttccagac aactataagg tgatttttct 300

 gcaaggaggt gggtgcggcc agttcagtgc tgtcccctta aacctcattg 350

 gcttgaaagc aggaaggtgt gcggactatg tggtgacagg agcttggtca 400

 gctaaggccg cagaagaagc caagaagttt gggactataa atatcgttca 450

 ccctaaactt gggagttata caaaaattcc agatccaagc acctggaacc 500

 tcaacccaga tgcctcctac gtgtattatt gcgcaaatga gacggtgcat 550

 ggtgtggagt ttgactttat acccgatgtc aagggagcag tactggtttg 600

 tgacatgtcc tcaaacttcc tgtccaagcc agtggatgtt tccaagtttg 650

 gtgtgatttt tgctggtgcc cagaagaatg ttggctctgc tggggtcacc 700

 gtggtgattg tccgtgatga cctgctgggg tttgccctcc gagagtgccc 750

 ctcggtcctg gaatacaagg tgcaggctgg aaacagctcc ttgtacaaca 800

 cgcctccatg tttcagcatc tacgtcatgg gcttggttct ggagtggatt 850

 aaaaacaatg gaggtgccgc ggccatggag aagcttagct ccatcaaatc 900

 tcaaacaatt tatgagatta ttgataattc tcaaggattc tacgtttgtc 950

 cagtggagcc ccaaaataga agcaagatga atattccatt ccgcattggc 1000

 aatgccaaag gagatgatgc tttagaaaaa agatttcttg ataaagctct 1050

 tgaactcaat atgttgtcct tgaaagggca taggtctgtg ggaggcatcc 1100

 gggcctctct gtataatgct gtcacaattg aagacgttca gaagctggcc 1150

 gccttcatga aaaaattttt ggagatgcat cagctatgaa cacatcctaa 1200

 ccaggatata ctctgttctt gaacaacata caaagtttaa agtaacttgg 1250

 ggatggctac aaaaagttaa cacagtattt ttctcaaatg aacatgttta 1300

 ttgcagattc ttcttttttg aaagaacaac agcaaaacat ccacaactct 1350

 gtaaagctgg tgggacctaa tgtcacctta attctgactt gaactggaag 1400

 cattttaaga aatcttgttg cttttctaac aaattcccgc gtattttgcc 1450

 tttgctgcta ctttttctag ttagatttca aacttgcctg tggacttaat 1500

 aatgcaagtt gcgattaatt atttctggag tcatgggaac acacagcaca 1550

 gagggtaggg gggccctcta ggtgctgaat ctacacatct gtggggtctc 1600

 ctgggttcag cggctgttga ttcaaggtca acattgacca ttggaggagt 1650

 ggtttaagag tgccaggcga agggcaaact gtagatcgat ctttatgctg 1700

 ttattacagg agaagtgaca tactttatat atgtttatat tagcaaggtc 1750

 tgtttttaat accatatact ttatatttct atacatttat atttctaata 1800

 atacagttat cactgatata tgtagacact tttagaattt attaaatcct 1850

 tgaccttgtg cattatagca ttccattagc aagagttgta ccccctcccc 1900

 agtcttcgcc ttcctctttt taagctgttt tatgaaaaag acctagaagt 1950

 tcttgattca tttttaccat tctttccata ggtagaagag aaagttgatt 2000

 ggttggttgt ttttcaatta tgccattaaa ctaaacattt ctgttaaatt 2050

 accctatcct ttgttctcta ctgttttctt tgtaatgtat gactacgaga 2100

 gtgatacttt gctgaaaagt ctttccccta ttgtttatct attgtcagta 2150

 ttttatgttg aatatgtaaa gaacattaaa gtcctaaaac atctaaaaaa 2200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2229

<210> 3568
<211> 370
<212> PRT
<213> Homo sapien

<400> 3568
 Met Asp Ala Pro Arg Gln Val Val Asn Phe Gly Pro Gly Pro Ala
   1               5                  10                  15

 Lys Leu Pro His Ser Val Leu Leu Glu Ile Gln Lys Glu Leu Leu
                  20                  25                  30

 Asp Tyr Lys Gly Val Gly Ile Ser Val Leu Glu Met Ser His Arg
                  35                  40                  45

 Ser Ser Asp Phe Ala Lys Ile Ile Asn Asn Thr Glu Asn Leu Val
                  50                  55                  60

 Arg Glu Leu Leu Ala Val Pro Asp Asn Tyr Lys Val Ile Phe Leu
                  65                  70                  75

 Gln Gly Gly Gly Cys Gly Gln Phe Ser Ala Val Pro Leu Asn Leu
                  80                  85                  90

 Ile Gly Leu Lys Ala Gly Arg Cys Ala Asp Tyr Val Val Thr Gly
                  95                 100                 105

 Ala Trp Ser Ala Lys Ala Ala Glu Glu Ala Lys Lys Phe Gly Thr
                 110                 115                 120

 Ile Asn Ile Val His Pro Lys Leu Gly Ser Tyr Thr Lys Ile Pro
                 125                 130                 135

 Asp Pro Ser Thr Trp Asn Leu Asn Pro Asp Ala Ser Tyr Val Tyr
                 140                 145                 150

 Tyr Cys Ala Asn Glu Thr Val His Gly Val Glu Phe Asp Phe Ile
                 155                 160                 165

 Pro Asp Val Lys Gly Ala Val Leu Val Cys Asp Met Ser Ser Asn
                 170                 175                 180

 Phe Leu Ser Lys Pro Val Asp Val Ser Lys Phe Gly Val Ile Phe
                 185                 190                 195

 Ala Gly Ala Gln Lys Asn Val Gly Ser Ala Gly Val Thr Val Val
                 200                 205                 210

 Ile Val Arg Asp Asp Leu Leu Gly Phe Ala Leu Arg Glu Cys Pro
                 215                 220                 225

 Ser Val Leu Glu Tyr Lys Val Gln Ala Gly Asn Ser Ser Leu Tyr
                 230                 235                 240

 Asn Thr Pro Pro Cys Phe Ser Ile Tyr Val Met Gly Leu Val Leu
                 245                 250                 255

 Glu Trp Ile Lys Asn Asn Gly Gly Ala Ala Ala Met Glu Lys Leu
                 260                 265                 270

 Ser Ser Ile Lys Ser Gln Thr Ile Tyr Glu Ile Ile Asp Asn Ser
                 275                 280                 285

 Gln Gly Phe Tyr Val Cys Pro Val Glu Pro Gln Asn Arg Ser Lys
                 290                 295                 300

 Met Asn Ile Pro Phe Arg Ile Gly Asn Ala Lys Gly Asp Asp Ala
                 305                 310                 315

 Leu Glu Lys Arg Phe Leu Asp Lys Ala Leu Glu Leu Asn Met Leu
                 320                 325                 330

 Ser Leu Lys Gly His Arg Ser Val Gly Gly Ile Arg Ala Ser Leu
                 335                 340                 345

 Tyr Asn Ala Val Thr Ile Glu Asp Val Gln Lys Leu Ala Ala Phe
                 350                 355                 360

 Met Lys Lys Phe Leu Glu Met His Gln Leu
                 365                 370

<210> 3569
<211> 1499
<212> DNA
<213> Homo sapien

<400> 3569
 tttaaactgc tagaaaggaa gagccgaata tttggctgga gtgattttta 50

 gacatttctc taccttaggg caccagagag gttcacttgc ccagggttcc 100

 atagctggtt ggtgccagag tccgaacgag aaaccaggtc ttctcagctc 150

 ctgtcaccca cagttttgca gacactgaat ttatgaggtg gattccattc 200

 aagcatgcac ataactagca gacacttctc ctaatcctcc tcaattcccc 250

 tttgcattgc tcagatacca caatcctttg caggttaaat cccttcacct 300

 tgtgaactca ttaggcaggg caatgtatat gaatccctga gtccttaaga 350

 acgtccttag gctgtgttag aaatgcagtt gccataggag taaccggccc 400

 ctgctgtcat ttggatgttc tctcttcccc aaaatccagc accaccttgg 450

 ttaagcaccc accatgtgcc tgcccacctg gctccttagg caatgttaca 500

 attaaccagg ttggttttga tgagggtcta gggcaaaatt tgaaccacca 550

 caacagccaa tgtgcacatc catgcagagg gttcagagat ggcctcggcc 600

 aaggatgcca ggcttcagct ctggaaggag ccctgggagg tgggagatct 650

 ttgtataaaa attggaaccc aaactataat tcccattagg gatatatatg 700

 ctcacatcac tcctgattca aagctcagaa gtggcctctc aggagaaata 750

 aaggtctctc tctctctctc tctctatctc acacacacac acacacacac 800

 acacacacag agagagagag agagagagag agagagagag agagagaggc 850

 cagcattcaa aattcccatg cttagggaat ccattgggac ttctccccag 900

 gatgtactga attcaaggaa gctttctcta ggtgtagcag aaactgctgc 950

 tgtcatgtct ctgctcacca ggacgtagct tctctctaca gacctttatt 1000

 tctttccctg gaggcttcag tccatgttga agtgtaaact ccactcagct 1050

 ccaggaggaa tcgtgttttc tttatcacca ggggcttctt ctacgagttg 1100

 cctttgatag ggaggccagg aggaagatag gcccaagctc aggggtggga 1150

 tcggggagca ggaagcctgt gggctttaga atcgaggtat tggtttctcc 1200

 ctgtcaccgt catccaccac ctgtgtgaac ttgagccatt tatcgaacct 1250

 cacggagccc caagtttctc atctgtaaac aaggggaatg agccctactt 1300

 tgtatggttg tcaagaggat ttgagacaat atgtataaag caatggacac 1350

 gcagaggaag tcaataagta caaggtaact ctgaaaatgc caccaaaggg 1400

 aggctaggga caggaaagcc atctccgcca acctcaagaa cgtggccccg 1450

 aagctgttcc aggaactggg catgtatgaa gataaaaaaa aaaaaaaaa 1499

<210> 3570
<211> 129
<212> PRT
<213> Homo sapien

<400> 3570
 Met Ala Ser Ala Lys Asp Ala Arg Leu Gln Leu Trp Lys Glu Pro
   1               5                  10                  15

 Trp Glu Val Gly Asp Leu Cys Ile Lys Ile Gly Thr Gln Thr Ile
                  20                  25                  30

 Ile Pro Ile Arg Asp Ile Tyr Ala His Ile Thr Pro Asp Ser Lys
                  35                  40                  45

 Leu Arg Ser Gly Leu Ser Gly Glu Ile Lys Val Ser Leu Ser Leu
                  50                  55                  60

 Ser Leu Tyr Leu Thr His Thr His Thr His Thr His Thr Gln Arg
                  65                  70                  75

 Glu Arg Glu Arg Glu Arg Glu Arg Glu Arg Glu Arg Pro Ala Phe
                  80                  85                  90

 Lys Ile Pro Met Leu Arg Glu Ser Ile Gly Thr Ser Pro Gln Asp
                  95                 100                 105

 Val Leu Asn Ser Arg Lys Leu Ser Leu Gly Val Ala Glu Thr Ala
                 110                 115                 120

 Ala Val Met Ser Leu Leu Thr Arg Thr
                 125

<210> 3571
<211> 2264
<212> DNA
<213> Homo sapien

<400> 3571
 gggatcaggc tcgtgaacat attcggcaaa acctagaaag tttcataaga 50

 caggactttc caggaactaa attgagcctg tttggctcct ccaaaaatgg 100

 atttgggttc aaacagagtg accttgacgt ctgtatgaca attaatgggc 150

 ttgaaactgc tgagggattg gactgtgtca gaactattga agaattagca 200

 agagtcctca gaaaacattc aggcctgaga aacatcttac ctattacaac 250

 agcaaaggtg ccaattgtga agttcttcca tttgagaagt ggtctggaag 300

 tagatatcag tttgtataac acattggccc ttcataacac aaggctttta 350

 tctgcttatt ccgccattga tcccagagtg aagtatttgt gctataccat 400

 gaaagtattt acaaagatat acaaaggtga aaagaaacct gaaatatttg 450

 ttgatggctg gaatatttat ttttttgatc aaatagatga actgcctacc 500

 tattggtcag aatgtggaaa aaatacagaa tctgttgggc agttatggtt 550

 gggccttctt cgtttctaca cagaggaatt tgattttaaa gaacatgtta 600

 ttagcatcag gagaaaaagt ctgcttacaa cttttaagaa acagtggacc 650

 tcaaaataca ttgttattga agatcccttt gatttgaatc ataatcttgg 700

 agctggatta tcaaggaaaa tgacaaattt tataatgaag gcttttatca 750

 atggtagaag agtatttggt attcctgtca agggatttcc aaaggactac 800

 ccctcaaaaa tggaatactt ttttgatcca gatgtgttaa ctgaaggaga 850

 gctggcccca aatgatagat gttgtcgaat ttgtggaaaa atcggacact 900

 tcatgaagga ctgtcctatg aggagaaaag taagacggcg gcgagatcag 950

 gaagatgccc tgaaccaaag ataccctgag aacaaggaaa aaagaagcaa 1000

 agaggacaaa gaaattcaca acaagtacac agaaagggag gtgtcaacaa 1050

 aagaagataa gcccatacag tgcacacctc agaaagccaa gccaatgcgg 1100

 gcagctgctg acctggggag ggagaagatc ctcaggccac cagtagaaaa 1150

 atggaagaga caggatgaca aagacttaag agaaaaacgt tgttttattt 1200

 gtggaagaga agggcacatt aaaaaggaat gcccacagtt taaaggctct 1250

 tcaggtagcc tttccagtaa atatatgact cagggaaaag cctcagcgaa 1300

 gaggacccag caggaatcat gagggaagga aaatgcagca ctctaaatgg 1350

 ccactcaggc gttcctattc actcggaaaa ttaggttcat ttcacaggac 1400

 acagcagtgt agatcaggct tcaacttaac atttaaggga aatgtcagat 1450

 ttttttttaa tttaatgaaa ttgttaatga ggaaaaattt ttaatatagt 1500

 cttatctacc acacatcccc atagatttaa ggattttaat agaaagtcat 1550

 gatgtatgta tttaagccac gttaaaagaa aaaatataac tatggaccgg 1600

 tattcagtga atacagtttc atggttttta attctttcaa agcacattaa 1650

 aaatggtgtg ctgataaacc ccaagtaaat taaccctttt tccgtataaa 1700

 tccatttttt gttttgaaga ggggaaatta tacttattgt tgtttactga 1750

 atcctggtgt gaaagcatat cagatatgta tgaactgcta ctgctgtact 1800

 tccgatttac ggacatcatt ttattgctat ttgtagacgt gataacatga 1850

 acatgagtac ctatttatgt gggccttcag tggatgggca gtgccactca 1900

 ggtctctggg gtttccctct ctaattttaa gtaaattgac atataactac 1950

 tatgcttata aaaatgaagt aaggaaaaca agtagtcctg tttgccacta 2000

 aaaacatttt caaaggaaaa ataaaatgaa agtacttttt actttttatg 2050

 atactcagaa attaggatga agaactttta aaattgctga aggtcaaaga 2100

 ggttatctct gccagtcaca agtgtggctg gtgtcattct gggtctgact 2150

 ggagccctcc tggactgttt ctttaatttc aaaagccctg cagacatagt 2200

 acctggtcag aactatgcct cggtttattt atcattttga aataaaatca 2250

 aaatttcaac ctgt 2264

<210> 3572
<211> 395
<212> PRT
<213> Homo sapien

<400> 3572
 Met Thr Ile Asn Gly Leu Glu Thr Ala Glu Gly Leu Asp Cys Val
   1               5                  10                  15

 Arg Thr Ile Glu Glu Leu Ala Arg Val Leu Arg Lys His Ser Gly
                  20                  25                  30

 Leu Arg Asn Ile Leu Pro Ile Thr Thr Ala Lys Val Pro Ile Val
                  35                  40                  45

 Lys Phe Phe His Leu Arg Ser Gly Leu Glu Val Asp Ile Ser Leu
                  50                  55                  60

 Tyr Asn Thr Leu Ala Leu His Asn Thr Arg Leu Leu Ser Ala Tyr
                  65                  70                  75

 Ser Ala Ile Asp Pro Arg Val Lys Tyr Leu Cys Tyr Thr Met Lys
                  80                  85                  90

 Val Phe Thr Lys Ile Tyr Lys Gly Glu Lys Lys Pro Glu Ile Phe
                  95                 100                 105

 Val Asp Gly Trp Asn Ile Tyr Phe Phe Asp Gln Ile Asp Glu Leu
                 110                 115                 120

 Pro Thr Tyr Trp Ser Glu Cys Gly Lys Asn Thr Glu Ser Val Gly
                 125                 130                 135

 Gln Leu Trp Leu Gly Leu Leu Arg Phe Tyr Thr Glu Glu Phe Asp
                 140                 145                 150

 Phe Lys Glu His Val Ile Ser Ile Arg Arg Lys Ser Leu Leu Thr
                 155                 160                 165

 Thr Phe Lys Lys Gln Trp Thr Ser Lys Tyr Ile Val Ile Glu Asp
                 170                 175                 180

 Pro Phe Asp Leu Asn His Asn Leu Gly Ala Gly Leu Ser Arg Lys
                 185                 190                 195

 Met Thr Asn Phe Ile Met Lys Ala Phe Ile Asn Gly Arg Arg Val
                 200                 205                 210

 Phe Gly Ile Pro Val Lys Gly Phe Pro Lys Asp Tyr Pro Ser Lys
                 215                 220                 225

 Met Glu Tyr Phe Phe Asp Pro Asp Val Leu Thr Glu Gly Glu Leu
                 230                 235                 240

 Ala Pro Asn Asp Arg Cys Cys Arg Ile Cys Gly Lys Ile Gly His
                 245                 250                 255

 Phe Met Lys Asp Cys Pro Met Arg Arg Lys Val Arg Arg Arg Arg
                 260                 265                 270

 Asp Gln Glu Asp Ala Leu Asn Gln Arg Tyr Pro Glu Asn Lys Glu
                 275                 280                 285

 Lys Arg Ser Lys Glu Asp Lys Glu Ile His Asn Lys Tyr Thr Glu
                 290                 295                 300

 Arg Glu Val Ser Thr Lys Glu Asp Lys Pro Ile Gln Cys Thr Pro
                 305                 310                 315

 Gln Lys Ala Lys Pro Met Arg Ala Ala Ala Asp Leu Gly Arg Glu
                 320                 325                 330

 Lys Ile Leu Arg Pro Pro Val Glu Lys Trp Lys Arg Gln Asp Asp
                 335                 340                 345

 Lys Asp Leu Arg Glu Lys Arg Cys Phe Ile Cys Gly Arg Glu Gly
                 350                 355                 360

 His Ile Lys Lys Glu Cys Pro Gln Phe Lys Gly Ser Ser Gly Ser
                 365                 370                 375

 Leu Ser Ser Lys Tyr Met Thr Gln Gly Lys Ala Ser Ala Lys Arg
                 380                 385                 390

 Thr Gln Gln Glu Ser
                 395

<210> 3573
<211> 1858
<212> DNA
<213> Homo sapien

<400> 3573
 ctgacctgct gggctgggac agcacaggac ccacagatat ctgctgccat 50

 ccacactctc cagattggtg tcctgggacc acgtggggat gctgctgtgg 100

 cttcttgtct tctctgctct gggtatccag gcctggggtg attcctcctg 150

 gaacaaaaca caagctaaac aggtatcaga ggggctccag tacctatttg 200

 agaacatctc ccagctcact gaaaaagatg tctccaccac ggtctctcgc 250

 aaggcatggg gggcagaagc tgttggctgc agtattcagc tgaccacgcc 300

 agtgaatgtc cttgttatac accatgtccc tggactggag tgtcacgacc 350

 agacagtctg cagccagaga ctgcgggaac tgcaggccca tcatgtccac 400

 aacaacagtg ggtgtgatgt ggcctacaac ttcctggttg gggatgatgg 450

 cagggtgtat gaaggtgttg gctggaatat ccaaggagtg cacacccaag 500

 gctacaacaa catctccctg ggctttgcct tcttcggcac taagaaaggc 550

 cacagtccca gccctgctgc cctgtcggcc atggaaaacc taatcaccta 600

 tgctgtccag aagggccacc tgtcatccag ttatgttcag ccacttcttg 650

 ggaaaggcga gaactgcctg gcccctcggc agaagacaag cctgaagaag 700

 cttgccccgg cattgtccca cggtctgtgt ggggagccag ggagaccact 750

 gtccaggatg actctcccag cgaagtatgg catcattatc cacactgccg 800

 ggaggacctg caacatttct gatgagtgcc gcctgctggt ccgggacatc 850

 cagtctttct acatagacag gctcaagtca tgcgacattg gttataactt 900

 cctggtgggc caggatggcg ccatttatga aggggtgggc tggaatgtcc 950

 aaggctcctc cacccctggc tacgatgaca ttgccctggg cattaccttc 1000

 atgggcacct tcacaggtat accacccaat gctgcagcac tagaggcagc 1050

 ccaagacctg atccagtgtg ccatggtcaa agggtacctg actcccaact 1100

 acctgctggt gggccacagt gatgtggccc gaaccttgtc tcctgggcag 1150

 gctttgtaca acatcatcag cacctggcct catttcaaac actgagagaa 1200

 gccccaggtc cttctgagac tgctttccct cccctgtcag gtctctcctg 1250

 tcctaaccat ccagcttggc tcaacacctt ttgccctcct cccctgccac 1300

 acagtcctgt gcctcctttt tcaggttggg atgatcatgc ctctcctgcc 1350

 aacatcctcc aagggcctcc aaactcatag ctggacattc acagccctct 1400

 gagtctgagt ccagatttct tctctcctta cttcctctcc cttggaaacc 1450

 caactcctca gccaggtgag acaatgggct ggttcttgtt tcatttctct 1500

 ctctctctcc attcccctct gcctggtgag ccttcccctg gtgtctgcct 1550

 ggcagccccc accacccacc tatcacccct cacccataac tcaggtcaac 1600

 gtgaccaacc ttccttgctt acacataaac ttgtatatat ttggatgtag 1650

 cccttattta atggctgtca ttatttatag atatgtctat ccttgctact 1700

 tggttgtgag tttctccagg ggaggaactg tgttttattc atctctatgt 1750

 cctctgtttc tcagcagtgt ctgaaattta atgggttcta ctgatgttta 1800

 ttagagaaat ggatgaataa atgaatgaag agatccaaaa aaaaaaaaaa 1850

 aaaaaaaa 1858

<210> 3574
<211> 368
<212> PRT
<213> Homo sapien

<400> 3574
 Met Leu Leu Trp Leu Leu Val Phe Ser Ala Leu Gly Ile Gln Ala
   1               5                  10                  15

 Trp Gly Asp Ser Ser Trp Asn Lys Thr Gln Ala Lys Gln Val Ser
                  20                  25                  30

 Glu Gly Leu Gln Tyr Leu Phe Glu Asn Ile Ser Gln Leu Thr Glu
                  35                  40                  45

 Lys Asp Val Ser Thr Thr Val Ser Arg Lys Ala Trp Gly Ala Glu
                  50                  55                  60

 Ala Val Gly Cys Ser Ile Gln Leu Thr Thr Pro Val Asn Val Leu
                  65                  70                  75

 Val Ile His His Val Pro Gly Leu Glu Cys His Asp Gln Thr Val
                  80                  85                  90

 Cys Ser Gln Arg Leu Arg Glu Leu Gln Ala His His Val His Asn
                  95                 100                 105

 Asn Ser Gly Cys Asp Val Ala Tyr Asn Phe Leu Val Gly Asp Asp
                 110                 115                 120

 Gly Arg Val Tyr Glu Gly Val Gly Trp Asn Ile Gln Gly Val His
                 125                 130                 135

 Thr Gln Gly Tyr Asn Asn Ile Ser Leu Gly Phe Ala Phe Phe Gly
                 140                 145                 150

 Thr Lys Lys Gly His Ser Pro Ser Pro Ala Ala Leu Ser Ala Met
                 155                 160                 165

 Glu Asn Leu Ile Thr Tyr Ala Val Gln Lys Gly His Leu Ser Ser
                 170                 175                 180

 Ser Tyr Val Gln Pro Leu Leu Gly Lys Gly Glu Asn Cys Leu Ala
                 185                 190                 195

 Pro Arg Gln Lys Thr Ser Leu Lys Lys Leu Ala Pro Ala Leu Ser
                 200                 205                 210

 His Gly Leu Cys Gly Glu Pro Gly Arg Pro Leu Ser Arg Met Thr
                 215                 220                 225

 Leu Pro Ala Lys Tyr Gly Ile Ile Ile His Thr Ala Gly Arg Thr
                 230                 235                 240

 Cys Asn Ile Ser Asp Glu Cys Arg Leu Leu Val Arg Asp Ile Gln
                 245                 250                 255

 Ser Phe Tyr Ile Asp Arg Leu Lys Ser Cys Asp Ile Gly Tyr Asn
                 260                 265                 270

 Phe Leu Val Gly Gln Asp Gly Ala Ile Tyr Glu Gly Val Gly Trp
                 275                 280                 285

 Asn Val Gln Gly Ser Ser Thr Pro Gly Tyr Asp Asp Ile Ala Leu
                 290                 295                 300

 Gly Ile Thr Phe Met Gly Thr Phe Thr Gly Ile Pro Pro Asn Ala
                 305                 310                 315

 Ala Ala Leu Glu Ala Ala Gln Asp Leu Ile Gln Cys Ala Met Val
                 320                 325                 330

 Lys Gly Tyr Leu Thr Pro Asn Tyr Leu Leu Val Gly His Ser Asp
                 335                 340                 345

 Val Ala Arg Thr Leu Ser Pro Gly Gln Ala Leu Tyr Asn Ile Ile
                 350                 355                 360

 Ser Thr Trp Pro His Phe Lys His
                 365

<210> 3575
<211> 2065
<212> DNA
<213> Homo sapien

<400> 3575
 gggacgcgag cgggatccaa acttccggtg cctgcagagc tcggagcggc 50

 ggaggcagag accgaggctg caccggcaga ggctgcgggg cggacgcgcg 100

 ggccggcgca gccatggtga agattagctt ccagcccgcc gtggctggca 150

 tcaagggcga caaggctgac aaggcgtcgg cgtcggcccc tgcgccggcc 200

 tcggccaccg agatcctgct gacgccggct agggaggagc agcccccaca 250

 acatcgatcc aagagggggg gctcagtggg cggcgtgtgc tacctgtcga 300

 tgggcatggt cgtgctgctc atgggcctcg tgttcgcctc tgtctacatc 350

 tacagatact tcttccttgc gcagctggcc cgagataact tcttccgctg 400

 tggtgtgctg tatgaggact ccctgtcctc ccaggtccgg actcagatgg 450

 agctggaaga ggatgtgaaa atctacctcg acgagaacta cgagcgcatc 500

 aacgtgcctg tgccccagtt tggcggcggt gaccctgcag acatcatcca 550

 tgacttccag cggggtctga ctgcgtacca tgatatctcc ctggacaagt 600

 gctatgtcat cgaactcaac accaccattg tgctgccccc tcgcaacttc 650

 tgggagctcc tcatgaacgt gaagaggggg acctacctgc cgcagacgta 700

 catcatccag gaggagatgg tggtcacgga gcatgtcagt gacaaggagg 750

 ccctggggtc cttcatctac cacctgtgca acgggaaaga cacctaccgg 800

 ctccggcgcc gggcaacgcg gaggcggatc aacaagcgtg gggccaagaa 850

 ctgcaatgcc atccgccact tcgagaacac cttcgtggtg gagacgctca 900

 tctgcggggt ggtgtgaggc cctcctcccc cagaaccccc tgccgtgttc 950

 ctcttttctt ctttccggct gctctctggc cctcctcctt ccccctgctt 1000

 agcttgtact ttggacgcgt ttctatagag gtgacatgtc tctccattcc 1050

 tctccaaccc tgcccacctc cctgtaccag agctgtgatc tctcggtggg 1100

 gggcccatct ctgctgacct gggtgtggcg gagggagagg cgatgctgca 1150

 aagtgttttc tgtgtcccac tgtcttgaag ctgggcctgc caaagcctgg 1200

 gcccacagct gcaccggcag cccaagggga aggaccggtt gggggagccg 1250

 ggcatgtgag gccctgggca aggggatggg gctgtggggg cggggcggca 1300

 tgggcttcag aagtatctgc acaattagaa aagtcctcag aagctttttc 1350

 ttggagggta cactttcttc actgtcccta ttcctagacc tggggcttga 1400

 gctgaggatg ggacgatgtg cccagggagg gacccaccag agcacaagag 1450

 aaggtggcta cctgggggtg tcccagggac tctgtcagtg ccttcagccc 1500

 accagcagga gcttggagtt tggggagtgg ggatgagtcc gtcaagcaca 1550

 actgttctct gagtggaacc aaagaagcaa ggagctagga cccccagtcc 1600

 tgccccccag gagcacaagc agggtcccct cagtcaaggc agtgggatgg 1650

 gcggctgagg aacggggcag gcaaggtcac tgctcagtca cgtccacggg 1700

 ggacgagccg tgggttctgc tgagtaggtg gagctcattg ctttctccaa 1750

 gcttggaact gttttgaaag ataacacaga gggaaaggga gagccacctg 1800

 gtacttgtcc accctgcctc ctctgttctg aaattccatc cccctcagct 1850

 taggggaatg cacctttttc cctttccttc tcacttttgc atgtttttac 1900

 tgatcattcg atatgctaac cgttctcagc cctgagcctt ggagaggagg 1950

 gctgtaacgc cttcagtcag tctctgggga tgaaactctt aaatgctttg 2000

 tatattttct caattagatc tcttttcaga agtgtctata gaacaataaa 2050

 aatcttttac ttctg 2065

<210> 3576
<211> 267
<212> PRT
<213> Homo sapien

<400> 3576
 Met Val Lys Ile Ser Phe Gln Pro Ala Val Ala Gly Ile Lys Gly
   1               5                  10                  15

 Asp Lys Ala Asp Lys Ala Ser Ala Ser Ala Pro Ala Pro Ala Ser
                  20                  25                  30

 Ala Thr Glu Ile Leu Leu Thr Pro Ala Arg Glu Glu Gln Pro Pro
                  35                  40                  45

 Gln His Arg Ser Lys Arg Gly Gly Ser Val Gly Gly Val Cys Tyr
                  50                  55                  60

 Leu Ser Met Gly Met Val Val Leu Leu Met Gly Leu Val Phe Ala
                  65                  70                  75

 Ser Val Tyr Ile Tyr Arg Tyr Phe Phe Leu Ala Gln Leu Ala Arg
                  80                  85                  90

 Asp Asn Phe Phe Arg Cys Gly Val Leu Tyr Glu Asp Ser Leu Ser
                  95                 100                 105

 Ser Gln Val Arg Thr Gln Met Glu Leu Glu Glu Asp Val Lys Ile
                 110                 115                 120

 Tyr Leu Asp Glu Asn Tyr Glu Arg Ile Asn Val Pro Val Pro Gln
                 125                 130                 135

 Phe Gly Gly Gly Asp Pro Ala Asp Ile Ile His Asp Phe Gln Arg
                 140                 145                 150

 Gly Leu Thr Ala Tyr His Asp Ile Ser Leu Asp Lys Cys Tyr Val
                 155                 160                 165

 Ile Glu Leu Asn Thr Thr Ile Val Leu Pro Pro Arg Asn Phe Trp
                 170                 175                 180

 Glu Leu Leu Met Asn Val Lys Arg Gly Thr Tyr Leu Pro Gln Thr
                 185                 190                 195

 Tyr Ile Ile Gln Glu Glu Met Val Val Thr Glu His Val Ser Asp
                 200                 205                 210

 Lys Glu Ala Leu Gly Ser Phe Ile Tyr His Leu Cys Asn Gly Lys
                 215                 220                 225

 Asp Thr Tyr Arg Leu Arg Arg Arg Ala Thr Arg Arg Arg Ile Asn
                 230                 235                 240

 Lys Arg Gly Ala Lys Asn Cys Asn Ala Ile Arg His Phe Glu Asn
                 245                 250                 255

 Thr Phe Val Val Glu Thr Leu Ile Cys Gly Val Val
                 260                 265

<210> 3577
<211> 2840
<212> DNA
<213> Homo sapien

<400> 3577
 ggtggggttg cgctcacaag gggcgaccgt cgccacggtg gcggccactg 50

 catcgcgtcc cacctccgcg gccctgggcg ccgtggtgtc gacgggcccc 100

 gagcctatga cgggccaggg ccagtcggcg tccgggtcgt cggcgtggag 150

 cacggtattc cgccacgtcc ggtatgagaa cctgatagcg ggcgtgagcg 200

 gcggcgtctt atccaacctt gcgctgcatc cgctcgacct cgtgaagatc 250

 cgcttcgccg tgagtgatgg attggaactg agaccgaaat ataatggaat 300

 tttacattgc ttgactacca tttggaaact tgatggacta cggggacttt 350

 atcaaggagt aaccccaaat atatggggtg caggtttatc ctggggactc 400

 tactttttct tttacaatgc catcaagtca tataaaacag aaggaagagc 450

 tgaacgttta gaggcaacag aataccttgt ctcagctgct gaagctggag 500

 ccatgaccct ctgcattaca aacccattat gggtaacaaa aactcgcctt 550

 atgttacagt atgatgctgt tgttaactcc ccacaccgac aatataaagg 600

 aatgtttgat acacttgtga aaatatataa gtatgaaggt gtgcgtggat 650

 tatataaggg atttgttcct gggctgtttg gaacatcgca tggtgccctt 700

 cagtttatgg catatgaatt gctgaagttg aagtacaacc agcatatcaa 750

 tagattacca gaagcccagt tgagcacagt agaatatata tctgttgcag 800

 cactatccaa aatatttgct gtcgcagcaa catacccata tcaagtcgta 850

 agagctcgtc ttcaggatca acacatgttt tacagtggtg taatagatgt 900

 aatcacaaag acatggagga aagaaggcgt cggtggattt tacaagggaa 950

 ttgctcctaa tttgattaga gtgactccag cctgctgtat tacctttgtg 1000

 gtatatgaaa acgtctcaca ttttttactt gaccttagag aaaagagaaa 1050

 gtaagctcaa agaggacaat tccagtatat ctgcccaagg cagcaacaag 1100

 ctcttttgtg tttaaggcat aaaagaagaa ttctgcatag aaacatggct 1150

 catattcgaa attgctctat agtcattaga agccagagaa ctgctaagtc 1200

 tcctgcaatg tttttctgct ttttgccttc cccatatata tggaacttgg 1250

 ctacctctgc ctgaaatggc tgccatcaac acaatgttaa aactgacacg 1300

 aaggatagag tttcacagat ttctacgttt tattggtgga agctgatttg 1350

 caacatttgc taaatggatt agatgaatgt acttcttttt gtgagcttac 1400

 ttgcctggat tgctttaaaa ttaacctttg tgcaatacca agaaaatagc 1450

 tctttaaaag aatgtctttg tatgtctcaa ggtaaattaa ggatttactg 1500

 aataaggtgt tgaccaaatc cagaccattt tattttattt ttttatttat 1550

 ttattttttg agatggagtc ttgctttgtc gcccaggctg gagtgcagtg 1600

 gcgtgatctc agctcactgc aacctccacc tcccgggttc acgccattct 1650

 cctgcctcag cctcctgagt agctgggact acaggcacct gccaccacgc 1700

 ctggctaact tttttttata ttttgagtag aaatggggtt tcaccatgtt 1750

 agccaggatg gtctcaatct cctgaccttg tgatccgcct gccttggcct 1800

 cccaaagtgc tgggattaca ggcgtgagcc actgcgcctg gccagaccat 1850

 tttagaattg ggaaatttta gtgagaaaaa atgcactgta aatatgcttt 1900

 agttttaatt cagttgggat gcactaccta gcgaaaattg agaaactata 1950

 tacttctcag agaaatatct gacatctatt gtcattccat tgctattttt 2000

 tttccccaga gacttccata atttaaaata aaatcctaga tccagttctt 2050

 gttttttggc ataaatactt aatctatttt aaatttataa aatctgagct 2100

 tctaggatcc agctgtgtca acctttattt agcatatata actataaatc 2150

 acttattaca gatgctaaat agatcacctt ttacagatgc tgaaatgttt 2200

 gggatatgtt tgttgacaag gtaaatggaa atgagaaact ttatacttca 2250

 gttttcagat atatggatct agatcccaaa taaatgatta atcttcattg 2300

 gtttctcaaa ttcaggttga aatacaaatt aatagccttt attgatttta 2350

 cttttatgag tcattgtaga catctataaa tataaaaggg cctgtaccca 2400

 aaggatgcca gaatactagt atttttattt atcgtaaaca tccacgagtg 2450

 ctgttgcact accatctatt tgttgtaaat aaaagtgttg ttttcaaagc 2500

 catctttaaa tagttcttta aaaataggtc ttttttttat attttggaaa 2550

 aggcattgtt tttaaagtaa agataaaatg gtaagtacct aattgtattt 2600

 actgtaatat cttataacat gcagatgaat gctttataag ttaaatatga 2650

 tgtatttttt catacttctg gattatacta taattcatat gaaatcttga 2700

 tattagtccc cacacggaaa aagtgaactg cagttgatat ttggtgttta 2750

 agatagcacc attgtttaaa taccgcctat gtactcccaa atgaataaaa 2800

 cataattctt gtcctctgag agcataaaaa aaaaaaaaaa 2840

<210> 3578
<211> 315
<212> PRT
<213> Homo sapien

<400> 3578
 Met Thr Gly Gln Gly Gln Ser Ala Ser Gly Ser Ser Ala Trp Ser
   1               5                  10                  15

 Thr Val Phe Arg His Val Arg Tyr Glu Asn Leu Ile Ala Gly Val
                  20                  25                  30

 Ser Gly Gly Val Leu Ser Asn Leu Ala Leu His Pro Leu Asp Leu
                  35                  40                  45

 Val Lys Ile Arg Phe Ala Val Ser Asp Gly Leu Glu Leu Arg Pro
                  50                  55                  60

 Lys Tyr Asn Gly Ile Leu His Cys Leu Thr Thr Ile Trp Lys Leu
                  65                  70                  75

 Asp Gly Leu Arg Gly Leu Tyr Gln Gly Val Thr Pro Asn Ile Trp
                  80                  85                  90

 Gly Ala Gly Leu Ser Trp Gly Leu Tyr Phe Phe Phe Tyr Asn Ala
                  95                 100                 105

 Ile Lys Ser Tyr Lys Thr Glu Gly Arg Ala Glu Arg Leu Glu Ala
                 110                 115                 120

 Thr Glu Tyr Leu Val Ser Ala Ala Glu Ala Gly Ala Met Thr Leu
                 125                 130                 135

 Cys Ile Thr Asn Pro Leu Trp Val Thr Lys Thr Arg Leu Met Leu
                 140                 145                 150

 Gln Tyr Asp Ala Val Val Asn Ser Pro His Arg Gln Tyr Lys Gly
                 155                 160                 165

 Met Phe Asp Thr Leu Val Lys Ile Tyr Lys Tyr Glu Gly Val Arg
                 170                 175                 180

 Gly Leu Tyr Lys Gly Phe Val Pro Gly Leu Phe Gly Thr Ser His
                 185                 190                 195

 Gly Ala Leu Gln Phe Met Ala Tyr Glu Leu Leu Lys Leu Lys Tyr
                 200                 205                 210

 Asn Gln His Ile Asn Arg Leu Pro Glu Ala Gln Leu Ser Thr Val
                 215                 220                 225

 Glu Tyr Ile Ser Val Ala Ala Leu Ser Lys Ile Phe Ala Val Ala
                 230                 235                 240

 Ala Thr Tyr Pro Tyr Gln Val Val Arg Ala Arg Leu Gln Asp Gln
                 245                 250                 255

 His Met Phe Tyr Ser Gly Val Ile Asp Val Ile Thr Lys Thr Trp
                 260                 265                 270

 Arg Lys Glu Gly Val Gly Gly Phe Tyr Lys Gly Ile Ala Pro Asn
                 275                 280                 285

 Leu Ile Arg Val Thr Pro Ala Cys Cys Ile Thr Phe Val Val Tyr
                 290                 295                 300

 Glu Asn Val Ser His Phe Leu Leu Asp Leu Arg Glu Lys Arg Lys
                 305                 310                 315

<210> 3579
<211> 446
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 180-181
<223> Unknown base

<400> 3579
 gattgccatt aaagcagaaa ttataaggtt gcaacaatat ttgtttctaa 50

 tcactggctt tctcaagagt atggattgac atattgtgtt atgaatgcac 100

 atctctcaga tgtgttgaag catccattgc atccattttt tattattttc 150

 ttagttttgt tcttggacaa atttaaacan nttaaaagat tattcaagat 200

 gaatttaaaa gtcaaccctt cacacagttt ccctactgta tgtagaatcc 250

 aggtgctgaa accaagtgtt tcttttccca tgctctttgt taaactccaa 300

 ttatagataa tttttccagt cttaagctct gtccaccttc aagtcaattc 350

 ataaccaagt ttttgaacgc tgctatgaat tgcactgtga aaagcactct 400

 tccctctcag ttttcgttca tcctgagcca gaatcaaaaa aaaaaa 446

<210> 3580
<211> 71
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 30-31
<223> unknown amino acid

<220>
<221> Unsure
<222> 180-181
<223> Unknown amino acid

<400> 3580
 Met Asn Ala His Leu Ser Asp Val Leu Lys His Pro Leu His Pro
   1               5                  10                  15

 Phe Phe Ile Ile Phe Leu Val Leu Phe Leu Asp Lys Phe Lys Xaa
                  20                  25                  30

 Xaa Lys Arg Leu Phe Lys Met Asn Leu Lys Val Asn Pro Ser His
                  35                  40                  45

 Ser Phe Pro Thr Val Cys Arg Ile Gln Val Leu Lys Pro Ser Val
                  50                  55                  60

 Ser Phe Pro Met Leu Phe Val Lys Leu Gln Leu
                  65                  70

<210> 3581
<211> 2071
<212> DNA
<213> Homo sapien

<400> 3581
 ggcacgaggc ctgggtcccg tcacatcctt cttgctcaac cactgggtgc 50

 acaggatgga aacttctatt ccctctctgg aagacagcgc gtggcttggc 100

 ttcacagagt tgtggctgga gaccgaagca gcccctttct caggcttact 150

 gtcaccagtc tgtctgtgtt aggggagagg ggagtccgct ctgtcctgaa 200

 ggcccagaga tggaaggaca agtggtaggc cgggtgttca ggctcttcca 250

 acgccgactg cttcaactcc gagcaggacc accccaggac aattcagggg 300

 aagctttaaa ggaaccagaa agggcccagg agcactcttt gcccaacttt 350

 gctggggggc agcacttctt tgaatacctt cttgtggttt ctctcaaaaa 400

 gaagcgttca gaggatgatt acgagcctat aatcacctac caatttccca 450

 agcgggagaa cctgcttcgg ggtcagcagg aggaggagga gcggctgctc 500

 aaagctatcc ccttgttctg cttcccagat gggaatgagt gggcatcact 550

 caccgagtat cccagggaga ccttctcctt cgttctgacc aatgtggatg 600

 ggagcagaaa gattggatac tgcaggcgcc tcttgcctgc cggccctggc 650

 cctcgccttc ccaaagtgta ctgcatcatc agctgcatcg gctgcttcgg 700

 cttgttctcc aagatcctgg atgaagtgga gaagagacat cagatctcca 750

 tggctgtcat ctacccgttc atgcagggcc tccgagaggc agccttccct 800

 gctcctggga agactgtcac tctcaagagc ttcatccccg actcaggcac 850

 tgagttcatt tcactgacac ggcccctgga ctcccaccta gaacatgtgg 900

 attttagttc tctattgcac tgtctcagtt ttgaacagat acttcagatc 950

 tttgcctctg ccgtgctgga gagaaaaatc atcttcctgg cggaaggtct 1000

 cagcaccttg tctcagtgca tccatgctgc tgccgcactg ctctacccct 1050

 tcagctgggc gcacacctac atccctgttg tccctgagag ccttctggcc 1100

 accgtctgct gccccacccc cttcatggtt ggagtacaaa tgcgcttcca 1150

 gcaggaggtc atggacagcc ctatggaaga ggtcctgctg gtcaatcttt 1200

 gtgaaggaac cttcttaatg tcggttggtg atgaaaaaga catcctgcca 1250

 ccgaagcttc aggatgacat cttagactct cttggtcagg ggatcaatga 1300

 gttaaagact gcagaacaaa tcaacgagca tgtttcaggc ccctttgtgc 1350

 agttctttgt caagattgtg ggccattatg cttcctatat caagcgggag 1400

 gcaaatgggc aaggccactt ccaagaaaga tccttctgta aggctctgac 1450

 ctccaagacc aaccgccgat ttgtgaagaa gtttgtgaag acacagctct 1500

 tctcactttt catccaggaa gccgagaaga gcaagaatcc tcctgcaggc 1550

 tatttccaac agaaaatact tgaatatgag gaacagaaga aacagaagaa 1600

 accaagggaa aaaactgtga aataagagct gtggtgaata agaatgacta 1650

 gagctacaca ccatttctgg acttcagccc ctgccagtgt ggcaggatca 1700

 gcaaaactgt cagctcccaa aatccatatc ctcactctga gtcttggtat 1750

 ccaggtattg cttcaaactg gtgtctgaga tttggatccc tggtattgat 1800

 ttctcaggac tttggagggc tctgacacca tgctcacaga actgggctca 1850

 gagctccatt ttttgcagag gtgacacagg taggaaacag tagtacatgt 1900

 gttgtagaca cttggttaga agctgctgca actgccctct cccatcatta 1950

 taacatcttc aacacagaac acactttgtg gtcgaaaggc tcagcctctc 2000

 tacatgaagt ctgtggacat gtaaggacga gagtaaagag gaaaatctta 2050

 taaaaaaaaa aaaaaaaaaa a 2071

<210> 3582
<211> 471
<212> PRT
<213> Homo sapien

<400> 3582
 Met Glu Gly Gln Val Val Gly Arg Val Phe Arg Leu Phe Gln Arg
   1               5                  10                  15

 Arg Leu Leu Gln Leu Arg Ala Gly Pro Pro Gln Asp Asn Ser Gly
                  20                  25                  30

 Glu Ala Leu Lys Glu Pro Glu Arg Ala Gln Glu His Ser Leu Pro
                  35                  40                  45

 Asn Phe Ala Gly Gly Gln His Phe Phe Glu Tyr Leu Leu Val Val
                  50                  55                  60

 Ser Leu Lys Lys Lys Arg Ser Glu Asp Asp Tyr Glu Pro Ile Ile
                  65                  70                  75

 Thr Tyr Gln Phe Pro Lys Arg Glu Asn Leu Leu Arg Gly Gln Gln
                  80                  85                  90

 Glu Glu Glu Glu Arg Leu Leu Lys Ala Ile Pro Leu Phe Cys Phe
                  95                 100                 105

 Pro Asp Gly Asn Glu Trp Ala Ser Leu Thr Glu Tyr Pro Arg Glu
                 110                 115                 120

 Thr Phe Ser Phe Val Leu Thr Asn Val Asp Gly Ser Arg Lys Ile
                 125                 130                 135

 Gly Tyr Cys Arg Arg Leu Leu Pro Ala Gly Pro Gly Pro Arg Leu
                 140                 145                 150

 Pro Lys Val Tyr Cys Ile Ile Ser Cys Ile Gly Cys Phe Gly Leu
                 155                 160                 165

 Phe Ser Lys Ile Leu Asp Glu Val Glu Lys Arg His Gln Ile Ser
                 170                 175                 180

 Met Ala Val Ile Tyr Pro Phe Met Gln Gly Leu Arg Glu Ala Ala
                 185                 190                 195

 Phe Pro Ala Pro Gly Lys Thr Val Thr Leu Lys Ser Phe Ile Pro
                 200                 205                 210

 Asp Ser Gly Thr Glu Phe Ile Ser Leu Thr Arg Pro Leu Asp Ser
                 215                 220                 225

 His Leu Glu His Val Asp Phe Ser Ser Leu Leu His Cys Leu Ser
                 230                 235                 240

 Phe Glu Gln Ile Leu Gln Ile Phe Ala Ser Ala Val Leu Glu Arg
                 245                 250                 255

 Lys Ile Ile Phe Leu Ala Glu Gly Leu Ser Thr Leu Ser Gln Cys
                 260                 265                 270

 Ile His Ala Ala Ala Ala Leu Leu Tyr Pro Phe Ser Trp Ala His
                 275                 280                 285

 Thr Tyr Ile Pro Val Val Pro Glu Ser Leu Leu Ala Thr Val Cys
                 290                 295                 300

 Cys Pro Thr Pro Phe Met Val Gly Val Gln Met Arg Phe Gln Gln
                 305                 310                 315

 Glu Val Met Asp Ser Pro Met Glu Glu Val Leu Leu Val Asn Leu
                 320                 325                 330

 Cys Glu Gly Thr Phe Leu Met Ser Val Gly Asp Glu Lys Asp Ile
                 335                 340                 345

 Leu Pro Pro Lys Leu Gln Asp Asp Ile Leu Asp Ser Leu Gly Gln
                 350                 355                 360

 Gly Ile Asn Glu Leu Lys Thr Ala Glu Gln Ile Asn Glu His Val
                 365                 370                 375

 Ser Gly Pro Phe Val Gln Phe Phe Val Lys Ile Val Gly His Tyr
                 380                 385                 390

 Ala Ser Tyr Ile Lys Arg Glu Ala Asn Gly Gln Gly His Phe Gln
                 395                 400                 405

 Glu Arg Ser Phe Cys Lys Ala Leu Thr Ser Lys Thr Asn Arg Arg
                 410                 415                 420

 Phe Val Lys Lys Phe Val Lys Thr Gln Leu Phe Ser Leu Phe Ile
                 425                 430                 435

 Gln Glu Ala Glu Lys Ser Lys Asn Pro Pro Ala Gly Tyr Phe Gln
                 440                 445                 450

 Gln Lys Ile Leu Glu Tyr Glu Glu Gln Lys Lys Gln Lys Lys Pro
                 455                 460                 465

 Arg Glu Lys Thr Val Lys
                 470

<210> 3583
<211> 2098
<212> DNA
<213> Homo sapien

<400> 3583
 gcaggagcac gtggagaggc cgggtagcca cagcggcagc tccagcccgg 50

 cccggcagcg acatggaaga tatacaaaca aatgcggaac tgaaaagcac 100

 tcaggagcag tctgtgcccg cagaaagtgc agcggttttg aatgactaca 150

 gtttaaccaa atctcatgaa atggaaaatg tggacagtgg agaaggccca 200

 gccaatgaag atgaagacat aggagatgat tcaatgaaag tgaaagatga 250

 atacagtgaa agagatgaga atgttttaaa gtcagaaccc atgggaaatg 300

 cagaagagcc tgaaatccct tacagctatt caagagaata taatgaatat 350

 gaaaacatta agttggagag acatgttgtc tcattcgata gtagcaggcc 400

 aaccagtgga aagatgaact gcgatgtgtg tggattatcc tgcatcagct 450

 tcaatgtctt aatggttcat aagcgaagcc atactggtga acgcccattc 500

 cagtgtaatc agtgtggggc atcttttact cagaaaggta acctcctccg 550

 ccacattaaa ctgcacacag gggaaaaacc ttttaagtgt cacctctgca 600

 actatgcatg ccaaagaaga gatgcgctca cggggcatct taggacacat 650

 tctgtggaga aaccctacaa atgtgagttt tgtggaagga gttacaagca 700

 gagaagttcc cttgaggagc acaaggagcg ctgccgtaca tttcttcaga 750

 gcactgaccc aggggacact gcaagtgcgg aggcaagaca catcaaagca 800

 gagatgggaa gtgaaagagc tctcgtactg gacagattag caagcaatgt 850

 ggcaaaacga aaaagctcaa tgcctcagaa attcattggt gagaagcgcc 900

 actgctttga tgtcaactat aattcaagtt acatgtatga gaaagagagt 950

 gagctcatac agacccgcat gatggaccaa gccatcaata acgccatcag 1000

 ctatcttggc gccgaagccc tgtgcccctt ggtccagaca ccgcctgctc 1050

 ccacctcgga gatggttcca gttatcagca gcatgtatcc catagccctc 1100

 acccgggctg agatgtcaaa cggtgcccct caagagctgg aaaggaaaag 1150

 catcctcctt ccagagaaga gcgtgccttc tgagagaggc ctctctccca 1200

 acaatagtgg ccacgactcc acggacactg acagcaacca tgaagaacgc 1250

 cagaatcaca tctatcagca aaatcacatg gtcctgtctc gggcccgcaa 1300

 tgggatgcca cttctgaagg aggttccccg ctcttacgaa ctcctcaagc 1350

 ccccgcccat ctgcccaaga gactctgtca aagtgatcga caaggaaggg 1400

 gaggtgatgg atgtgtatcg gtgtgaccac tgccgcgtcc tcttcctgga 1450

 ctatgtgatg ttcacgattc acatgggctg ccacggcttc cgtgaccctt 1500

 tcgagtgtaa catgtgtgga gatcgaagcc atgatcggta tgaattctcg 1550

 tctcacatag ccagaggaga acacagaagc ctgctgaagt gaatatctgg 1600

 tctcagggat tgctcctatg tattcagcat cgtttctaaa aacagttgac 1650

 ctcgcctaac agattgctct caaaacatac tcagttccaa acttcttttc 1700

 ataccatttt tagctgtgtt cacaggggta gccagagaaa cactgtcttc 1750

 cttcagaaat tattcgcagg tctagcatat tattactttt gtgaaacctt 1800

 tgttttccca tcagggactt gaattttatg gaatttaaaa gccaaaaagg 1850

 tatttggtca ttatcttcta cagcagtgga atgagtggtc ccggagatgt 1900

 gctatatgaa acattctttc tgagatatat caaccacacg tggaaaagcc 1950

 tttcagtcat acatgcaaat ccacaaagag gaagagctga ccagctgacc 2000

 ttgctgggaa gcctcaccct tctgcccttc acaggctgaa gggttaagat 2050

 ctaatctccc taatctaaat gacagtctaa gagtaagtaa aagaacag 2098

<210> 3584
<211> 509
<212> PRT
<213> Homo sapien

<400> 3584
 Met Glu Asp Ile Gln Thr Asn Ala Glu Leu Lys Ser Thr Gln Glu
   1               5                  10                  15

 Gln Ser Val Pro Ala Glu Ser Ala Ala Val Leu Asn Asp Tyr Ser
                  20                  25                  30

 Leu Thr Lys Ser His Glu Met Glu Asn Val Asp Ser Gly Glu Gly
                  35                  40                  45

 Pro Ala Asn Glu Asp Glu Asp Ile Gly Asp Asp Ser Met Lys Val
                  50                  55                  60

 Lys Asp Glu Tyr Ser Glu Arg Asp Glu Asn Val Leu Lys Ser Glu
                  65                  70                  75

 Pro Met Gly Asn Ala Glu Glu Pro Glu Ile Pro Tyr Ser Tyr Ser
                  80                  85                  90

 Arg Glu Tyr Asn Glu Tyr Glu Asn Ile Lys Leu Glu Arg His Val
                  95                 100                 105

 Val Ser Phe Asp Ser Ser Arg Pro Thr Ser Gly Lys Met Asn Cys
                 110                 115                 120

 Asp Val Cys Gly Leu Ser Cys Ile Ser Phe Asn Val Leu Met Val
                 125                 130                 135

 His Lys Arg Ser His Thr Gly Glu Arg Pro Phe Gln Cys Asn Gln
                 140                 145                 150

 Cys Gly Ala Ser Phe Thr Gln Lys Gly Asn Leu Leu Arg His Ile
                 155                 160                 165

 Lys Leu His Thr Gly Glu Lys Pro Phe Lys Cys His Leu Cys Asn
                 170                 175                 180

 Tyr Ala Cys Gln Arg Arg Asp Ala Leu Thr Gly His Leu Arg Thr
                 185                 190                 195

 His Ser Val Glu Lys Pro Tyr Lys Cys Glu Phe Cys Gly Arg Ser
                 200                 205                 210

 Tyr Lys Gln Arg Ser Ser Leu Glu Glu His Lys Glu Arg Cys Arg
                 215                 220                 225

 Thr Phe Leu Gln Ser Thr Asp Pro Gly Asp Thr Ala Ser Ala Glu
                 230                 235                 240

 Ala Arg His Ile Lys Ala Glu Met Gly Ser Glu Arg Ala Leu Val
                 245                 250                 255

 Leu Asp Arg Leu Ala Ser Asn Val Ala Lys Arg Lys Ser Ser Met
                 260                 265                 270

 Pro Gln Lys Phe Ile Gly Glu Lys Arg His Cys Phe Asp Val Asn
                 275                 280                 285

 Tyr Asn Ser Ser Tyr Met Tyr Glu Lys Glu Ser Glu Leu Ile Gln
                 290                 295                 300

 Thr Arg Met Met Asp Gln Ala Ile Asn Asn Ala Ile Ser Tyr Leu
                 305                 310                 315

 Gly Ala Glu Ala Leu Cys Pro Leu Val Gln Thr Pro Pro Ala Pro
                 320                 325                 330

 Thr Ser Glu Met Val Pro Val Ile Ser Ser Met Tyr Pro Ile Ala
                 335                 340                 345

 Leu Thr Arg Ala Glu Met Ser Asn Gly Ala Pro Gln Glu Leu Glu
                 350                 355                 360

 Arg Lys Ser Ile Leu Leu Pro Glu Lys Ser Val Pro Ser Glu Arg
                 365                 370                 375

 Gly Leu Ser Pro Asn Asn Ser Gly His Asp Ser Thr Asp Thr Asp
                 380                 385                 390

 Ser Asn His Glu Glu Arg Gln Asn His Ile Tyr Gln Gln Asn His
                 395                 400                 405

 Met Val Leu Ser Arg Ala Arg Asn Gly Met Pro Leu Leu Lys Glu
                 410                 415                 420

 Val Pro Arg Ser Tyr Glu Leu Leu Lys Pro Pro Pro Ile Cys Pro
                 425                 430                 435

 Arg Asp Ser Val Lys Val Ile Asp Lys Glu Gly Glu Val Met Asp
                 440                 445                 450

 Val Tyr Arg Cys Asp His Cys Arg Val Leu Phe Leu Asp Tyr Val
                 455                 460                 465

 Met Phe Thr Ile His Met Gly Cys His Gly Phe Arg Asp Pro Phe
                 470                 475                 480

 Glu Cys Asn Met Cys Gly Asp Arg Ser His Asp Arg Tyr Glu Phe
                 485                 490                 495

 Ser Ser His Ile Ala Arg Gly Glu His Arg Ser Leu Leu Lys
                 500                 505

<210> 3585
<211> 1047
<212> DNA
<213> Homo sapien

<400> 3585
 ctgtgagtga cacacgctga gtggggtgaa gggaaatgct ggtgaatttc 50

 attttgaggt gtgggttgct gttagtcact ctgtctcttg ccattgccaa 100

 gcacaagcaa tcttccttca ccaaaagttg ttacccaagg ggaacattgt 150

 cccaagctgt tgacgctctc tatatcaaag cagcatggct caaagcaacg 200

 attccagaag accgcataaa aaatatacga ttattaaaaa agaaaacaaa 250

 aaagcagttt atgaaaaact gtcaatttca agaacagctt ctgtccttct 300

 tcatggaaga cgtttttggt caactgcaat tgcaaggctg caagaaaata 350

 cgctttgtgg aggactttca tagccttagg cagaaattga gccactgtat 400

 ttcctgtgct tcatcagcta gagagatgaa atccattacc aggatgaaaa 450

 gaatatttta taggattgga aacaaaggaa tctacaaagc catcagtgaa 500

 ctggatattc ttctttcctg gattaaaaaa ttattggaaa gcagtcagta 550

 aaccaaagcc aagtacattg attttacagt tattttgaaa tacaataaga 600

 actgctagaa atatgtttat aacagtctat ttcttttaaa aactttttaa 650

 cataatactg acggcatgtt aggtgattca gaatagacaa gaaggattta 700

 gtaaattaac gttttggata taagttgtca ctaatttgca cattttctgt 750

 gttttcaaat aatgtttcca ttctgaacat gttttgtcat tcacaagtac 800

 attgtgtcaa cttaatttaa agtatgtaac ctgaattaac tcgtgtaata 850

 tttgtgtgtg gagtgggatg tggggggtgg agggggaatg acagatttct 900

 ggaatgcaat gtaatgttac tgagacttaa atagatgtta tgtatatgat 950

 tgtctgttta agtgtttgaa aattgttaat tatgcccagt gtgaacttag 1000

 tacttaacac attttgattt taattaaata aattgggttt ccttctc 1047

<210> 3586
<211> 171
<212> PRT
<213> Homo sapien

<400> 3586
 Met Leu Val Asn Phe Ile Leu Arg Cys Gly Leu Leu Leu Val Thr
   1               5                  10                  15

 Leu Ser Leu Ala Ile Ala Lys His Lys Gln Ser Ser Phe Thr Lys
                  20                  25                  30

 Ser Cys Tyr Pro Arg Gly Thr Leu Ser Gln Ala Val Asp Ala Leu
                  35                  40                  45

 Tyr Ile Lys Ala Ala Trp Leu Lys Ala Thr Ile Pro Glu Asp Arg
                  50                  55                  60

 Ile Lys Asn Ile Arg Leu Leu Lys Lys Lys Thr Lys Lys Gln Phe
                  65                  70                  75

 Met Lys Asn Cys Gln Phe Gln Glu Gln Leu Leu Ser Phe Phe Met
                  80                  85                  90

 Glu Asp Val Phe Gly Gln Leu Gln Leu Gln Gly Cys Lys Lys Ile
                  95                 100                 105

 Arg Phe Val Glu Asp Phe His Ser Leu Arg Gln Lys Leu Ser His
                 110                 115                 120

 Cys Ile Ser Cys Ala Ser Ser Ala Arg Glu Met Lys Ser Ile Thr
                 125                 130                 135

 Arg Met Lys Arg Ile Phe Tyr Arg Ile Gly Asn Lys Gly Ile Tyr
                 140                 145                 150

 Lys Ala Ile Ser Glu Leu Asp Ile Leu Leu Ser Trp Ile Lys Lys
                 155                 160                 165

 Leu Leu Glu Ser Ser Gln
                 170

<210> 3587
<211> 2035
<212> DNA
<213> Homo sapien

<400> 3587
 tccctgtcct gcgcccgcgc gccccgggag cctacccagc acgcgctccg 50

 cgcccactgg ttccctccag ccgccgccgt ccagccgagt ccccactccg 100

 gagtcgccgc tgccgcgggg acatggtcct ctgcgttcag ggacctcgtc 150

 ctttgctggc tgtggagcgg actgggcagc ggcccctgtg ggccccgtcc 200

 ctggaactgc ccaagccagt catgcagccc ttgcctgctg gggccttcct 250

 cgaggaggtg gcagagggta ccccagccca gacagagagt gagccaaagg 300

 tgctggaccc agaggaggat ctgctgtgca tagccaagac cttctcctac 350

 cttcgggaat ctggctggta ttggggttcc attacggcca gcgaggcccg 400

 acaacacctg cagaagatgc cagaaggcac gttcttagta cgtgacagca 450

 cgcaccccag ctacctgttc acgctgtcag tgaaaaccac tcgtggcccc 500

 accaatgtac gcattgagta tgccgactcc agcttccgtc tggactccaa 550

 ctgcttgtcc aggccacgca tcctggcctt tccggatgtg gtcagccttg 600

 tgcagcacta tgtggcctcc tgcactgctg atacccgaag cgacagcccc 650

 gatcctgctc ccaccccggc cctgcctatg cctaaggagg atgcgcctag 700

 tgacccagca ctgcctgctc ctccaccagc cactgctgta cacctaaaac 750

 tggtgcagcc ctttgtacgc agaagcagtg cccgcagcct gcaacacctg 800

 tgccgccttg tcatcaaccg tctggtggcc gacgtggact gcctgccact 850

 gccccggcgc atggccgact acctccgaca gtaccccttc cagctctgac 900

 tgtacggggc aatctgccca ccctcaccca gtcgcaccct ggaggggaca 950

 tcagccccag ctggacttgg gcccccactg tccctcctcc aggcatcctg 1000

 gtgcctgcat acctctggca gctggcccag gaagagccag caagagcaag 1050

 gcatgggaga ggggaggtgt cacacaactt ggaggtaaat gcccccaggc 1100

 cgcatgtggc ttcattatac tgagccatgt gtcagaggat ggggagacag 1150

 gcaggacctt gtctcacctg tgggctgggc ccagacctcc actcgcttgc 1200

 ctgccctggc cacctgaact gtatgggcac tctcagccct ggtttttcaa 1250

 tccccagggt cgggtaggac ccctactggc agccagcctc tgtttctggg 1300

 aggatgacat gcagaggaac tgagatcgac agtgactagt gaccccttgt 1350

 tgaggggtaa gccaggctag gggactgcac aattatacac tatttattta 1400

 tttattctcc ttggggttgg tgtcaggggc gagccaaccc cacctctatg 1450

 ccctgagccc tggtagtcca gagaccccaa ctctgccctg gcttctctgg 1500

 ttcttccctg tggaaagccc atcctgagac atcttgctgg aaccaaggca 1550

 atcctggatg tcctggtact gacccacccg tctgtgaatg tgtccactct 1600

 cttctgcccc cagccatatt tggggaggat ggacaactac aataggtaag 1650

 aaaatgcagc cggagcctca gtccccagca gagcctgtgt ctcaccccct 1700

 cacaggacag agctgtatct gcatagagct ggtctcactg tggcgcaggc 1750

 cccgggggga gtgcctgtgc tgtcaggaag agggggtgct ggtttgaggg 1800

 ccaccactgc agttctgcta ggtctgcttc ctgcccagga aggtgcctgc 1850

 acatgagagg agagaaatac acgtctgata agacttcatg aaataataat 1900

 tatagcaaag aacagtttgg tggtcttttc tcttccactg atttttctgt 1950

 aatgacatta tacctttatt acctctttat tttattacct ctataataaa 2000

 atgatacctt tttcatgtaa aaaaaaaaaa aaaaa 2035

<210> 3588
<211> 258
<212> PRT
<213> Homo sapien

<400> 3588
 Met Val Leu Cys Val Gln Gly Pro Arg Pro Leu Leu Ala Val Glu
   1               5                  10                  15

 Arg Thr Gly Gln Arg Pro Leu Trp Ala Pro Ser Leu Glu Leu Pro
                  20                  25                  30

 Lys Pro Val Met Gln Pro Leu Pro Ala Gly Ala Phe Leu Glu Glu
                  35                  40                  45

 Val Ala Glu Gly Thr Pro Ala Gln Thr Glu Ser Glu Pro Lys Val
                  50                  55                  60

 Leu Asp Pro Glu Glu Asp Leu Leu Cys Ile Ala Lys Thr Phe Ser
                  65                  70                  75

 Tyr Leu Arg Glu Ser Gly Trp Tyr Trp Gly Ser Ile Thr Ala Ser
                  80                  85                  90

 Glu Ala Arg Gln His Leu Gln Lys Met Pro Glu Gly Thr Phe Leu
                  95                 100                 105

 Val Arg Asp Ser Thr His Pro Ser Tyr Leu Phe Thr Leu Ser Val
                 110                 115                 120

 Lys Thr Thr Arg Gly Pro Thr Asn Val Arg Ile Glu Tyr Ala Asp
                 125                 130                 135

 Ser Ser Phe Arg Leu Asp Ser Asn Cys Leu Ser Arg Pro Arg Ile
                 140                 145                 150

 Leu Ala Phe Pro Asp Val Val Ser Leu Val Gln His Tyr Val Ala
                 155                 160                 165

 Ser Cys Thr Ala Asp Thr Arg Ser Asp Ser Pro Asp Pro Ala Pro
                 170                 175                 180

 Thr Pro Ala Leu Pro Met Pro Lys Glu Asp Ala Pro Ser Asp Pro
                 185                 190                 195

 Ala Leu Pro Ala Pro Pro Pro Ala Thr Ala Val His Leu Lys Leu
                 200                 205                 210

 Val Gln Pro Phe Val Arg Arg Ser Ser Ala Arg Ser Leu Gln His
                 215                 220                 225

 Leu Cys Arg Leu Val Ile Asn Arg Leu Val Ala Asp Val Asp Cys
                 230                 235                 240

 Leu Pro Leu Pro Arg Arg Met Ala Asp Tyr Leu Arg Gln Tyr Pro
                 245                 250                 255

 Phe Gln Leu


<210> 3589
<211> 9120
<212> DNA
<213> Homo sapien

<400> 3589
 gcggccgccg ccctcgccac cccgcctgcc cactcccgcc gccgccccgc 50

 tctcgctttc cccccggcct cccctcgccc cttcccctcc cccttcccgg 100

 cgcactcggg gggctgggaa cgagctgcca tgtgatgcgc gtcccctccg 150

 cgagctttcg gtgacccacg aactgcccac ctcgccggct gccgggaggg 200

 ggctgcgagc cgggaagacg cggggaagag gaggcggaaa aggacgcaaa 250

 gttctccggc gagcgcattc attcacatag ctcccagttt taacatttcg 300

 ccacctactg aagacatcat ttgggaccaa gctgatgagc ccttgaagca 350

 cagcagataa gagtgttgct gttgatcatc tttgcctggg aagttgaatg 400

 ataaagccag aagaaagcat gctttctgat catttgcagc tgtctgcttc 450

 agaaagtgag ggctccagga atgaggagaa tcttcaagaa cttcctcgca 500

 ctgtgacatg tctgatccct tgctcccatc cctgcagcat gaacaaggtg 550

 gacactcact gacctgtcac aaggttgccc cacaaaactt tggggtccat 600

 gtctgaatgg attgccagag ccttctcatc tctcccttcg cccagttccc 650

 tgcatcctaa gactcgaagg cagcacagga cctggaaaaa ttacatggtg 700

 tgaacggcat gtctgtggat gagaagcctg actcccccat gtatgtgtat 750

 gagtccacag tccactgcac caacatcctc ctgggcctca atgaccagcg 800

 gaaaaaggat attctctgtg acgtgacttt gatcgtggag aggaaggagt 850

 tccgggccca ccgggctgtg ctggccgcat gcagtgaata tttttggcag 900

 gcgctggttg gacagacaaa aaatgatttg gtggtcagct tgcctgagga 950

 ggtcacagcc aggggctttg ggccgctgtt acagtttgcc tacactgcca 1000

 agctgttact cagcagagaa aacatccgcg aggtcatccg ctgtgctgag 1050

 ttcctgcgca tgcacaacct ggaggactcc tgcttcagct tcctgcagac 1100

 ccagctcctg aacagtgagg atggcctgtt tgtgtgccgg aaggatgctg 1150

 cgtgccagcg cccacacgag gactgcgaga actctgcagg agaggaggag 1200

 gatgaagagg aggagacgat ggattcagag acggccaaga tggcttgccc 1250

 cagggaccag atgcttccag agcccatcag ctttgaggcc gccgccatcc 1300

 ccgtagcaga gaaggaagaa gccctgctgc ccgagcctga cgtgcccaca 1350

 gacaccaagg agagctcaga aaaggacgcg ttaacgcagt accccagata 1400

 caagaaatac cagcttgcat gtaccaagaa tgtctataat gcatcatcac 1450

 acagtacctc aggttttgca agcacattcc gggaagataa ctctagcaac 1500

 agcctcaagc cggggcttgc cagggggcag attaaaagtg agccgcccag 1550

 tgaagagaat gaggaagaga gcatcacgct ctgcctgtct ggagatgagc 1600

 ctgacgccaa ggacagagcg ggggatgtcg agatggaccg gaaacagccc 1650

 agccctgccc ctacccccac ggccccagct ggggccgcct gcctggagag 1700

 atccaggagc gtggcctcgc cctcctgctt aaggtctctg ttcagcataa 1750

 cgaaaagtgt ggagctgtct ggcctgccca gtacatctca gcagcacttt 1800

 gccaggagtc cagcctgccc ttttgacaag gggatcactc agggtgacct 1850

 taaaactgac tacacccctt tcacagggaa ttatggacag ccccacgtgg 1900

 gccagaagga ggtgtccaac ttcaccatgg ggtcgcccct cagggggcct 1950

 gggttggagg ctctctgtaa acaggaggga gagctggacc ggaggagcgt 2000

 gatcttctcc tccagcgctt gtgaccaagt gagcacctcg gtgcattctt 2050

 attctggggt gagcagtttg gacaaagacc tctctgagcc ggtgccaaag 2100

 ggtctgtggg tgggagccgg ccagtccctc cccagctcgc aggcctactc 2150

 ccacggtggg ctgatggccg accacttgcc aggaaggatg cggcccaaca 2200

 ccagctgccc ggtgccaatc aaagtctgcc ctcgctcacc ccccttggag 2250

 accaggacca ggacttccag ctcctgctct tcctattcct acgcggagga 2300

 cgggagcggg ggctcaccct gcagcctccc tctctgtgag ttctcctcct 2350

 cgccctgttc ccagggagcc agattccttg ccacagaaca tcaggaacca 2400

 ggcctgatgg gagatggaat gtacaaccaa gtgcggcccc aaattaaatg 2450

 tgagcagtct tatggaacca actccagtga cgaatccgga tcgttctcgg 2500

 aagcagacag tgagtcgtgt cctgtgcagg acaggggcca ggaggtaaaa 2550

 cttccttttc ctgtagatca aatcacagat cttccaagga acgatttcca 2600

 gatgatgatt aaaatgcaca agctaacctc agaacagtta gagtttattc 2650

 atgatgtccg acggcgcagc aagaaccgca tcgcggccca gcgctgccgc 2700

 aaaaggaaac tggactgtat tcagaattta gaatgtgaaa tccgcaaatt 2750

 ggtgtgtgag aaagagaaac tgttgtcaga gaggaatcaa ctgaaagcat 2800

 gcatggggga actgttggac aacttctcct gcctttccca ggaagtttgc 2850

 cgagacatcc agagccccga gcagatccag gccctgcatc ggtattgccc 2900

 tgtcctcaga cccatggact tgcccacggc ctccagtatt aaccctgcgc 2950

 ccttgggtgc tgagcagaac attgcggcct cccaatgcgc agtgggggaa 3000

 aacgtgccct gctgcttgga gccaggcgcg gctccccccg gacccccctg 3050

 ggcacccagc aacacctccg agaattgtac ctctgggagg agactagaag 3100

 gcactgaccc gggaaccttc tcagagagag gacctcctct tgaacccagg 3150

 agccaaacag tgaccgtgga cttctgccag gaaatgactg ataagtgtac 3200

 aactgacgaa cagcccagga aagattatac ctagtgactc ggctctgcct 3250

 cccagtccgc acacctctcc catccaggcg ttcttcagtc agcctgtggc 3300

 actgttcatc tgctgtcccg aagaaaccga gaacacattt ggtgcacact 3350

 acagcggtct tagcagcaat actgttccga agtatcctct cctcttctcg 3400

 agcaggagtg atagttacct tcacaatggt gctacccctt gcccaggcaa 3450

 ggaaagacag cagtgatgac actgtctgtc tgtggctcaa tttcagtctt 3500

 cacagggata gactacaaca cctctaggcc ccaaccacgg attttttttc 3550

 tcagtggccc atgtcacaaa ccctatctca ggaatttctt ctgaatgttc 3600

 aatttttttc attgaagaca gcttctatac acatcaaagt tttatagcta 3650

 gactgtacat attatatata atatatatat aaaaaatata tatatatata 3700

 tatatccata tgcaaaagtc ctgcatgcct caactttctc atcctaaaac 3750

 tggaaactta tttctcattt agaaacaggt tccaacattc ctcttctttt 3800

 gtctctgatg ctagaactag tttggtaact gttaacgtgg tcatttttct 3850

 tgcttcacag ttcaattttc aattcgtact tatttatgga caaaattcag 3900

 tgttggaagc tttttcccaa ggttttattt cagatttctt tttcgtttgg 3950

 tttggttttg gcacctccaa gtggtgtcat ttgagcattg taggtttgtt 4000

 ttttgtttgt ttggggggtt ttgtttgttt ttgtttttgt ttttgttttc 4050

 cttgcagata ctgtacagta atggtcaact ttgccacttg cactgagttt 4100

 tgggtcaaac ctattttctt aaatgaagtt gtaacttcgg tataactcaa 4150

 gtatactgta tattctttgc ttttagttaa aaaagtaaaa cattttagct 4200

 aattaaaaag cactcaggtg ataattatgt aggaaaaaca atcttgccaa 4250

 ataatgaatt catcctagga tgtgtagaca ataatctgct tgaatatttt 4300

 tatatttcac ctcctcccca cctttcccta agcaaagttt aaacgcagat 4350

 agagagttca gagttgatgc tggatgttca gattcctaag tggggagaga 4400

 gtttggacat ctcactcaaa agtacatcag aaaaacagga atccgtgatt 4450

 ttataccaga actcagcagg cattggctcc tagaaatcaa gttagaaagt 4500

 tttcacccag ggagtaagtc ccattcattt caacacgtcc tgaggcctcg 4550

 gcttgctctt ggaagtggtg tgcagtagga cctgctcccc tgaaggacgg 4600

 ggccaaccag ccactggctt tcctgcccag gcttggcctc ccaggacatc 4650

 tggcctgagg ggatttgaat cacagccccg aaggtcctgc cttcacccca 4700

 ttgggagaga gcagggcatc ctggcatctg cgatccatcc ctgacacagg 4750

 ctgacacatt ctttctcctt tccttctcca aaggcttgga gttttcttct 4800

 gaggtttttc tgccagtgtc ttgtctgaag gcagacttca ttctgaggct 4850

 ttggacaagc tattcaccgg gaaccctccc tgtccccttc ccgaatcaca 4900

 cacataccct accctcacct gatgataatt ttctcttctt gctgcaaaac 4950

 tggttggctt gcaacccaga gagagcagct tcccttggct ctgggggccg 5000

 tgttggcccc agccacgttt acaggaaggt gtgccccaga ggaggaggaa 5050

 tcagctccct cgctccagtg gccttgggtc cgggtctcac tgagcagccc 5100

 gagggccact ccagcccggc tggggaagag agtcctgaac ggtttgatgt 5150

 ggggatgggg tggtgggcag tggggaatag atggttgact ttgtttcttt 5200

 atttgtgcca ttgtttggac aatattaaag ctgcatgtaa aaggggaaat 5250

 tagtatatga tgtaggctaa aagtgaaatc atagtaacat atgttttagt 5300

 attattaact tttttctgta caaatattag cactaaatgt ttaaatatgt 5350

 atgaatgcca gaaatttgtc agttcatgca gtaggataaa aaaaaaaaaa 5400

 aaaaaaaaag ggcttttctt tttaaacagt tccactttta aaacctgcct 5450

 ctgggttttt gttttttctt gtttgtgtgt gtgtgtgtgt gtgtgtgtgt 5500

 gtgtgtgtgt gtgtgtgtgt gtctgaaaca gatcttgata aagctctgtg 5550

 ttggagctgc tggtttttgt tatggttgtt ggaatttctt ggcctactag 5600

 gacagttctg tgcttcacca tgaggtttgc ctttgtggaa aactcgtggg 5650

 tgacagtgag aatataaact caatgtgaat cacgtgatac ttcggcaggc 5700

 gtgtgttaca gtggagtcag ctgacagtat tttgcttttt aactctattg 5750

 ttgcctttcc aagtgacctc tcctcttctt ttaaaaaaag aacactttct 5800

 gctcatatca taaccaggtc caacccagct tcttggcatg aggtttaccc 5850

 tggtaacaac tcatgtgcaa ctggtagtct tgaccacatt ccatccattt 5900

 cctcaggttt ctgtggttca gtagcccaga cctgtttggc agccatttct 5950

 agcaggggcg gggcctcttt atttctctcc accctaactc agacctcacc 6000

 ttcctcccac ccacccctgc cttgcttttc ttcctcttcc cccaacctaa 6050

 cttctgccat gggaactggt taaaaacact gctctaaaaa ccatcttcca 6100

 atttcataga gatttctcac aagttatttc attcataatc caccatgaac 6150

 agtgactagc ttcgtgcagt tgttcatgtg atgtgtgtgt gtcttttcct 6200

 attcagaact atgtgcttgt caaaattatt tctgggttga ttcaaaggga 6250

 ggacttgctg gggaccagaa tccaaacggc ctcaagtgga attttaaaac 6300

 ctagcctgtc tcttttccct gggatccctc tgtcaacccc acgcctttta 6350

 ggaaaaagaa aagtgagtga acagcaagga agagtgtttg cacagtacag 6400

 taacatttgg ttgttcttaa ggctcttttc ttacaaaaat aagagaccct 6450

 ccaaccacgg gctgtttagg aggatgcctg cttgggtctc caaatggctg 6500

 gggtaggaat ggttgttggg gcagagccag tggaggtgag tgaccctgag 6550

 actaatgaac atcccaccta aatccagtcc tccccttgga tctgcctttg 6600

 tcctgcttgt gtatccaggc aacctctttt caagttggtc aggctttgga 6650

 caggtgagtg atttgctgta tgtgtttgtt tctctgcgtt acctgggggt 6700

 gccttgatta aaatcgaact ttattacata ctgattctgg aacaaaacag 6750

 ttagaaaaac tttaaacttt aaaaaaaaaa aaaccgacaa agttacgagg 6800

 ccatcctgct atttatcttc tgagttccca gcaatgactc aggcatcaga 6850

 gatgatgctg cagtggaaaa cctgactctg tgtgtctgca actgaatgtt 6900

 gtgcgagtaa tttattaact gtctttctaa aggtttgctg cttttaagat 6950

 gcactataat tcgggatgta atccttacat tgcttttcca aggaagggaa 7000

 caaaagtcta gtgattagta tgccaactgc cactactcct tcaaaaggag 7050

 ccaggaccag cgacaagact catgagagga ctggctaaag tgaagtgtgc 7100

 acagtgtgaa gtttaatgct gttgtcaaga ggcctaaacc cacattttct 7150

 cttttaatat tttatgattg ccatcaaaga agaagaaaaa gaaggaacag 7200

 acaaaggttt gaaaatgata agcctgttaa gacaccaaaa actcctgtcc 7250

 cgtgaagctg cttgacatcc tgtggagtag cataatcctc tcaaaatgag 7300

 gaagagctgc ctgcaaagct ttctcaagtc cctatttggc tacctacttc 7350

 tctacattat gccccattta aactaggagc tgtcttagaa atgacttcaa 7400

 actgcttcac tattgcttac agtttaggag gagtctcaga tccagaagga 7450

 gcaagaatca agtttggtcc tcaaatgact gtaaatagac taaagaacaa 7500

 ggtgtttttt gtttttgttt ttgttttcta agaataaagc tgttcgttgt 7550

 atcatgagtt agtgtttctt ccccaaactg aagactgtgt tggaagtgca 7600

 atttctggtg agtcagtcca caatacaatg ccctgtgtgg agttggtatt 7650

 catacaggaa atctgtgtgc acgaggcatt gtgtgttgaa agtgtatgtt 7700

 tatagtactg cctgagccat ctcatgaccc cagcgtccaa aaccgatgct 7750

 gtagaacaga acatatctgt cacaaatagg tgtgtgcaaa tagcatttgt 7800

 acatagaaaa gtctcattgt ggcagattga gcataaatta ttcaactgac 7850

 ggtgcaaaaa cattacttgc aaagaaaagt ttatagtatt ttcctacact 7900

 ccaccctggg agatgatatt tctatcaaat gaatatcagt gcattttaaa 7950

 tgtaatatga aaacgatgct gccattttgt gaagaatacc cacttggttg 8000

 cagaggccaa ctttcatagc tttgatttaa tgttgtgaca cggtgtatgc 8050

 attttgctgt caagcaatgg ataaacagct ctgactttca ttctcattcc 8100

 agtttattga cctcagataa aacactggcc cttcttagaa gcagaagtgt 8150

 gcaccaagac cattcatttc aggtagactc acattcagtg ccaagtgctc 8200

 ccatgggaat aatcagacgc atatgttgcg aaagagtgaa gggacttgga 8250

 caaagagggg ttttcctaca gatggatgct cagtcttcta ccaaaacatg 8300

 tttggaggca gaactatgac ctccccttaa gtcctaacaa tgtattttgt 8350

 gtgtgcaaat cctgggatgc ccgtttcacg ctctgacata aagacatggc 8400

 acctctagtg agtgatcagg aagattccat atgcatttgg gagcttcagg 8450

 tgcttgttag acacagtgag ccattcaagg caagcaccac ctttgctagt 8500

 gaggccaaga gagcctgtga caatttgaca atttgttcca gaaccagtct 8550

 gatgcaagtg cacctctaat atatgcctta caaactccag aggccatatt 8600

 caaaacaggg tcttctcagt gtatgcaagg ggctgcagcc cctcttctct 8650

 tcctccccag gttgaacaat acggacagtt ttcacacata tctacctgta 8700

 taaccctctg tacctctcat aactggtcaa cgactgtaac aggttacatc 8750

 aggtgttttt ctacatactt tttacacaga ttctatgcga ttaatgtaat 8800

 ttaattcaat gcatcatttt attgtactag ttcttaggct tgtccttatt 8850

 tttttctaag tgattgtggt ttttctcgtg gtttttattg taaaaaatga 8900

 aaggctgttg atgcttattc tctgtaacta agaattttac cttttggggg 8950

 aaaaaagcat tgctatgaac taatggaatt ggaacttcat ttactcattg 9000

 taaatacact attgtgcaaa aaaagttttc actcaattga attgctagtg 9050

 ttaactgaat tttgtctaga caccatttct gttgatgaaa taaagacata 9100

 tcattatgca ttgtaaactg 9120

<210> 3590
<211> 841
<212> PRT
<213> Homo sapien

<400> 3590
 Met Ser Val Asp Glu Lys Pro Asp Ser Pro Met Tyr Val Tyr Glu
   1               5                  10                  15

 Ser Thr Val His Cys Thr Asn Ile Leu Leu Gly Leu Asn Asp Gln
                  20                  25                  30

 Arg Lys Lys Asp Ile Leu Cys Asp Val Thr Leu Ile Val Glu Arg
                  35                  40                  45

 Lys Glu Phe Arg Ala His Arg Ala Val Leu Ala Ala Cys Ser Glu
                  50                  55                  60

 Tyr Phe Trp Gln Ala Leu Val Gly Gln Thr Lys Asn Asp Leu Val
                  65                  70                  75

 Val Ser Leu Pro Glu Glu Val Thr Ala Arg Gly Phe Gly Pro Leu
                  80                  85                  90

 Leu Gln Phe Ala Tyr Thr Ala Lys Leu Leu Leu Ser Arg Glu Asn
                  95                 100                 105

 Ile Arg Glu Val Ile Arg Cys Ala Glu Phe Leu Arg Met His Asn
                 110                 115                 120

 Leu Glu Asp Ser Cys Phe Ser Phe Leu Gln Thr Gln Leu Leu Asn
                 125                 130                 135

 Ser Glu Asp Gly Leu Phe Val Cys Arg Lys Asp Ala Ala Cys Gln
                 140                 145                 150

 Arg Pro His Glu Asp Cys Glu Asn Ser Ala Gly Glu Glu Glu Asp
                 155                 160                 165

 Glu Glu Glu Glu Thr Met Asp Ser Glu Thr Ala Lys Met Ala Cys
                 170                 175                 180

 Pro Arg Asp Gln Met Leu Pro Glu Pro Ile Ser Phe Glu Ala Ala
                 185                 190                 195

 Ala Ile Pro Val Ala Glu Lys Glu Glu Ala Leu Leu Pro Glu Pro
                 200                 205                 210

 Asp Val Pro Thr Asp Thr Lys Glu Ser Ser Glu Lys Asp Ala Leu
                 215                 220                 225

 Thr Gln Tyr Pro Arg Tyr Lys Lys Tyr Gln Leu Ala Cys Thr Lys
                 230                 235                 240

 Asn Val Tyr Asn Ala Ser Ser His Ser Thr Ser Gly Phe Ala Ser
                 245                 250                 255

 Thr Phe Arg Glu Asp Asn Ser Ser Asn Ser Leu Lys Pro Gly Leu
                 260                 265                 270

 Ala Arg Gly Gln Ile Lys Ser Glu Pro Pro Ser Glu Glu Asn Glu
                 275                 280                 285

 Glu Glu Ser Ile Thr Leu Cys Leu Ser Gly Asp Glu Pro Asp Ala
                 290                 295                 300

 Lys Asp Arg Ala Gly Asp Val Glu Met Asp Arg Lys Gln Pro Ser
                 305                 310                 315

 Pro Ala Pro Thr Pro Thr Ala Pro Ala Gly Ala Ala Cys Leu Glu
                 320                 325                 330

 Arg Ser Arg Ser Val Ala Ser Pro Ser Cys Leu Arg Ser Leu Phe
                 335                 340                 345

 Ser Ile Thr Lys Ser Val Glu Leu Ser Gly Leu Pro Ser Thr Ser
                 350                 355                 360

 Gln Gln His Phe Ala Arg Ser Pro Ala Cys Pro Phe Asp Lys Gly
                 365                 370                 375

 Ile Thr Gln Gly Asp Leu Lys Thr Asp Tyr Thr Pro Phe Thr Gly
                 380                 385                 390

 Asn Tyr Gly Gln Pro His Val Gly Gln Lys Glu Val Ser Asn Phe
                 395                 400                 405

 Thr Met Gly Ser Pro Leu Arg Gly Pro Gly Leu Glu Ala Leu Cys
                 410                 415                 420

 Lys Gln Glu Gly Glu Leu Asp Arg Arg Ser Val Ile Phe Ser Ser
                 425                 430                 435

 Ser Ala Cys Asp Gln Val Ser Thr Ser Val His Ser Tyr Ser Gly
                 440                 445                 450

 Val Ser Ser Leu Asp Lys Asp Leu Ser Glu Pro Val Pro Lys Gly
                 455                 460                 465

 Leu Trp Val Gly Ala Gly Gln Ser Leu Pro Ser Ser Gln Ala Tyr
                 470                 475                 480

 Ser His Gly Gly Leu Met Ala Asp His Leu Pro Gly Arg Met Arg
                 485                 490                 495

 Pro Asn Thr Ser Cys Pro Val Pro Ile Lys Val Cys Pro Arg Ser
                 500                 505                 510

 Pro Pro Leu Glu Thr Arg Thr Arg Thr Ser Ser Ser Cys Ser Ser
                 515                 520                 525

 Tyr Ser Tyr Ala Glu Asp Gly Ser Gly Gly Ser Pro Cys Ser Leu
                 530                 535                 540

 Pro Leu Cys Glu Phe Ser Ser Ser Pro Cys Ser Gln Gly Ala Arg
                 545                 550                 555

 Phe Leu Ala Thr Glu His Gln Glu Pro Gly Leu Met Gly Asp Gly
                 560                 565                 570

 Met Tyr Asn Gln Val Arg Pro Gln Ile Lys Cys Glu Gln Ser Tyr
                 575                 580                 585

 Gly Thr Asn Ser Ser Asp Glu Ser Gly Ser Phe Ser Glu Ala Asp
                 590                 595                 600

 Ser Glu Ser Cys Pro Val Gln Asp Arg Gly Gln Glu Val Lys Leu
                 605                 610                 615

 Pro Phe Pro Val Asp Gln Ile Thr Asp Leu Pro Arg Asn Asp Phe
                 620                 625                 630

 Gln Met Met Ile Lys Met His Lys Leu Thr Ser Glu Gln Leu Glu
                 635                 640                 645

 Phe Ile His Asp Val Arg Arg Arg Ser Lys Asn Arg Ile Ala Ala
                 650                 655                 660

 Gln Arg Cys Arg Lys Arg Lys Leu Asp Cys Ile Gln Asn Leu Glu
                 665                 670                 675

 Cys Glu Ile Arg Lys Leu Val Cys Glu Lys Glu Lys Leu Leu Ser
                 680                 685                 690

 Glu Arg Asn Gln Leu Lys Ala Cys Met Gly Glu Leu Leu Asp Asn
                 695                 700                 705

 Phe Ser Cys Leu Ser Gln Glu Val Cys Arg Asp Ile Gln Ser Pro
                 710                 715                 720

 Glu Gln Ile Gln Ala Leu His Arg Tyr Cys Pro Val Leu Arg Pro
                 725                 730                 735

 Met Asp Leu Pro Thr Ala Ser Ser Ile Asn Pro Ala Pro Leu Gly
                 740                 745                 750

 Ala Glu Gln Asn Ile Ala Ala Ser Gln Cys Ala Val Gly Glu Asn
                 755                 760                 765

 Val Pro Cys Cys Leu Glu Pro Gly Ala Ala Pro Pro Gly Pro Pro
                 770                 775                 780

 Trp Ala Pro Ser Asn Thr Ser Glu Asn Cys Thr Ser Gly Arg Arg
                 785                 790                 795

 Leu Glu Gly Thr Asp Pro Gly Thr Phe Ser Glu Arg Gly Pro Pro
                 800                 805                 810

 Leu Glu Pro Arg Ser Gln Thr Val Thr Val Asp Phe Cys Gln Glu
                 815                 820                 825

 Met Thr Asp Lys Cys Thr Thr Asp Glu Gln Pro Arg Lys Asp Tyr
                 830                 835                 840

 Thr


<210> 3591
<211> 2712
<212> DNA
<213> Homo sapien

<400> 3591
 gtcatgttct tcgcgccctg gtgtggacac tgccagcggc tgcagccgac 50

 ttggaatgac ctgggagaca aatacaacag catggaagat gccaaagtct 100

 atgtggctaa agtggactgc acggcccact ccgacgtgtg ctccgcccag 150

 ggggtgcgag gataccccac cttaaagctt ttcaagccag gccaagaagc 200

 tgtgaagtac cagggtcctc gggacttcca gacactggaa aactggatgc 250

 tgcagacact gaacgaggag ccagtgacac cagagccgga agtggaaccg 300

 cccagtgccc ccgagctcaa gcaagggctg tatgagctct cagcaagcaa 350

 ctttgagctg cacgttgcac aaggcgacca ctttatcaag ttcttcgctc 400

 cgtggtgtgg tcactgcaaa gccctggctc caacctggga gcagctggct 450

 ctgggccttg aacattccga aactgtcaag attggcaagg ttgattgtac 500

 acagcactat gaactctgct ccggaaacca ggttcgtggc tatcccactc 550

 ttctctggtt ccgagatggg aaaaaggtgg atcagtacaa gggaaagcgg 600

 gatttggagt cactgaggga gtacgtggag tcgcagctgc agcgcacaga 650

 gactggagcg acggagaccg tcacgccctc agaggccccg gtgctggcag 700

 ctgagcccga ggctgacaag ggcactgtgt tggcactcac tgaaaataac 750

 ttcgatgaca ccattgcaga aggaataacc ttcatcaagt tttatgctcc 800

 atggtgtggt cattgtaaga ctctggctcc tacttgggag gaactctcta 850

 aaaaggaatt ccctggtctg gcgggggtca agatcgccga agtagactgc 900

 actgctgaac ggaatatctg cagcaagtat tcggtacgag gctaccccac 950

 gttattgctt ttccgaggag ggaagaaagt cagtgagcac agtggaggca 1000

 gagaccttga ctcgttacac cgctttgtcc tgagccaagc gaaagacgaa 1050

 ctttaggaac acagttggag gtcacctctc ctgcccagct cccgcaccct 1100

 gcgtttagga gttcagtccc acagaggcca ctgggttccc agtggtggct 1150

 gttcagaaag cagaacatac taagcgtgag gtatcttctt tgtgtgtgtg 1200

 ttttccaagc caacacactc tacagattct ttattaaatg tgtaactcat 1250

 ggtcactgtg taaacatttt cagtggcgat atatcccctt tgaccttctc 1300

 ttgatgaaat ttacatggtt tcctttgaga ctaaaatagc gttgagggaa 1350

 atgaaattgc tggactattt gtggctcctg agttgagtga ttttggtgaa 1400

 agaaagcaca tccaaagcat agtttacctg cccacgagtt ctggaaaggt 1450

 ggccttgtgg cagtattgac gttcctctga tcttaaggtc acagttgact 1500

 caatactgtg ttggtccgta gcatggagca gattgaaatg caaaaaccca 1550

 cacctctgga agataccttc acggccgctg ctggagcttc tgttgctgtg 1600

 aatacttctc tcagtgtgag aggttagccg tgatgaaagc agcgttactt 1650

 ctgaccgtgc ctgagtaaga gaatgctgat gccataactt tatgtgtcga 1700

 tacttgtcaa atcagttact gttcagggga tccttctgtt tctcacgggg 1750

 tgaaacatgt ctttagttcc tcatgttaac acgaagccag agcccacatg 1800

 aactgttgga tgtcttcctt agaaagggta ggcatggaaa attccacgag 1850

 gctcattctc agtatctcat taactcattg aaagattcca gttgtatttg 1900

 tcacctgggg tgacaagacc agacaggctt tcccaggcct gggtatccag 1950

 ggaggctctg cagccctgct gaagggccct aactagagtt ctagagtttc 2000

 tgattctgtt tctcagtagt ccttttagag gcttgctata cttggtctgc 2050

 ttcaaggagg tcgaccttct aatgtatgaa gaatgggatg catttgatct 2100

 caagaccaaa gacagatgtc agtgggctgc tctggccctg gtgtgcacgg 2150

 ctgtggcagc tgttgatgcc agtgtcctct aactcatgct gtccttgtga 2200

 ttaaacacct ctatctccct tgggaataag cacatacagg cttaagctct 2250

 aagatagata ggtgtttgtc cttttaccat cgagctactt cccataataa 2300

 ccactttgca tccaacactc ttcacccacc tcccatacgc aaggggatgt 2350

 ggatacttgg cccaaagtaa ctggtggtag gaatcttaga aacaagacca 2400

 cttatactgt ctgtctgagg cagaagataa cagcagcatc tcgaccagcc 2450

 tctgccttaa aggaaatctt tattaatcac gtatggttca cagataattc 2500

 tttttttaaa aaaacccaac ctcctagaga agcacaactg tcaagagtct 2550

 tgtacacaca acttcagctt tgcatcacga gtcttgtatt ccaagaaaat 2600

 caaagtggta caatttgttt gtttacacta tgatactttc taaataaact 2650

 cttttttttt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2700

 aaaaaaaaaa ac 2712

<210> 3592
<211> 324
<212> PRT
<213> Homo sapien

<400> 3592
 Met Glu Asp Ala Lys Val Tyr Val Ala Lys Val Asp Cys Thr Ala
   1               5                  10                  15

 His Ser Asp Val Cys Ser Ala Gln Gly Val Arg Gly Tyr Pro Thr
                  20                  25                  30

 Leu Lys Leu Phe Lys Pro Gly Gln Glu Ala Val Lys Tyr Gln Gly
                  35                  40                  45

 Pro Arg Asp Phe Gln Thr Leu Glu Asn Trp Met Leu Gln Thr Leu
                  50                  55                  60

 Asn Glu Glu Pro Val Thr Pro Glu Pro Glu Val Glu Pro Pro Ser
                  65                  70                  75

 Ala Pro Glu Leu Lys Gln Gly Leu Tyr Glu Leu Ser Ala Ser Asn
                  80                  85                  90

 Phe Glu Leu His Val Ala Gln Gly Asp His Phe Ile Lys Phe Phe
                  95                 100                 105

 Ala Pro Trp Cys Gly His Cys Lys Ala Leu Ala Pro Thr Trp Glu
                 110                 115                 120

 Gln Leu Ala Leu Gly Leu Glu His Ser Glu Thr Val Lys Ile Gly
                 125                 130                 135

 Lys Val Asp Cys Thr Gln His Tyr Glu Leu Cys Ser Gly Asn Gln
                 140                 145                 150

 Val Arg Gly Tyr Pro Thr Leu Leu Trp Phe Arg Asp Gly Lys Lys
                 155                 160                 165

 Val Asp Gln Tyr Lys Gly Lys Arg Asp Leu Glu Ser Leu Arg Glu
                 170                 175                 180

 Tyr Val Glu Ser Gln Leu Gln Arg Thr Glu Thr Gly Ala Thr Glu
                 185                 190                 195

 Thr Val Thr Pro Ser Glu Ala Pro Val Leu Ala Ala Glu Pro Glu
                 200                 205                 210

 Ala Asp Lys Gly Thr Val Leu Ala Leu Thr Glu Asn Asn Phe Asp
                 215                 220                 225

 Asp Thr Ile Ala Glu Gly Ile Thr Phe Ile Lys Phe Tyr Ala Pro
                 230                 235                 240

 Trp Cys Gly His Cys Lys Thr Leu Ala Pro Thr Trp Glu Glu Leu
                 245                 250                 255

 Ser Lys Lys Glu Phe Pro Gly Leu Ala Gly Val Lys Ile Ala Glu
                 260                 265                 270

 Val Asp Cys Thr Ala Glu Arg Asn Ile Cys Ser Lys Tyr Ser Val
                 275                 280                 285

 Arg Gly Tyr Pro Thr Leu Leu Leu Phe Arg Gly Gly Lys Lys Val
                 290                 295                 300

 Ser Glu His Ser Gly Gly Arg Asp Leu Asp Ser Leu His Arg Phe
                 305                 310                 315

 Val Leu Ser Gln Ala Lys Asp Glu Leu
                 320

<210> 3593
<211> 3379
<212> DNA
<213> Homo sapien

<400> 3593
 ctggcctggg cctgaagtga gtgagaggca catgaagaga agtattcaag 50

 tatttataca gataggaatc aagataatca acaatgtctg tcactgagga 100

 agacctgtgc caccatatga aagtagtagt tcgtgtacgt ccggaaaaca 150

 ctaaagaaaa agcagctgga tttcataaag tggttcatgt tgtggataaa 200

 catatcctag tttttgatcc caaacaagaa gaagtcagtt ttttccatgg 250

 aaagaaaact acaaatcaaa atgttataaa gaaacaaaat aaggatctta 300

 aatttgtatt tgatgctgtt tttgatgaaa cgtcaactca gtcagaagtt 350

 tttgaacaca ctactaagcc aattcttcgt agttttttga atggatataa 400

 ttgcacagta cttgcctatg gtgccactgg tgctgggaag acccacacta 450

 tgctaggatc agctgatgaa cctggagtga tgtatctaac aatgttacac 500

 ctttacaaat gcatggatga gattaaagaa gagaaaatat gtagtactgc 550

 agtttcatat ctggaggtat ataatgaaca gattcgtgat ctcttagtaa 600

 attcagggcc acttgctgtc cgggaagata cccaaaaagg ggtggtcgtt 650

 catggactta ctttacacca gcccaaatcc tcagaagaaa ttttacattt 700

 attggataat ggaaacaaaa acaggacaca acatcccact gatatgaatg 750

 ccacatcttc tcgttctcat gctgttttcc aaatttactt gcgacaacaa 800

 gacaaaacag caagtatcaa tcaaaatgtc cgtattgcca agatgtcact 850

 cattgacctg gcaggatctg agcgagcaag tacttccggt gctaagggga 900

 cccgatttgt agaaggcaca aatattaata gatcactttt agctcttggg 950

 aatgtcatca atgccttagc agattcaaag agaaagaatc agcatatccc 1000

 ttacagaaat agtaagctta ctcgcttgtt aaaggattct cttggaggaa 1050

 actgtcaaac tataatgata gctgctgtta gtccttcctc tgtattctac 1100

 gatgacacat ataacactct taagtatgct aaccgggcaa aggacattaa 1150

 atcttctttg aagagcaatg ttcttaatgt caataatcat ataactcaat 1200

 atgtaaagat ctgtaatgag cagaaggcag agattttatt gttaaaagaa 1250

 aaactaaaag cctatgaaga acagaaagcc ttcactaatg aaaatgacca 1300

 agcaaagtta atgatttcaa accctcagga aaaagaaatc gaaaggtttc 1350

 aagaaatcct gaactgcttg ttccagaatc gagaagaaat tagacaagaa 1400

 tatctgaagt tggaaatgtt acttaaagaa aatgaactta aatcattcta 1450

 ccaacaacag tgccataaac aaatagaaat gatgtgttct gaagacaaag 1500

 tagaaaaggc cactggaaaa cgagatcata gacttgcaat gttgaaaact 1550

 cgtcgctcct acctggagaa aaggagggag gaggaattga agcaatttga 1600

 tgagaatact aattggctcc atcgtgtcga aaaagaaatg ggactcttaa 1650

 gtcaaaacgg tcatattcca aaggaactca agaaagatct tcattgtcac 1700

 catttgcacc tccagaacaa agatttgaaa gcacaaatta gacatatgat 1750

 ggatctagct tgtcttcagg aacagcaaca caggcagact gaagcagtat 1800

 tgaatgcttt acttccaacc ctaagaaaac aatattgcac attaaaagaa 1850

 gccggcctgt caaatgctgc ttttgaatct gacttcaaag agatcgaaca 1900

 tttggtagag aggaaaaaag tggtagtttg ggctgaccaa actggcgaac 1950

 aaccaaagca aaacgatcta cccgggattt ctgttcttat gaccttttca 2000

 caacttggac cagttcagcc tattccttgt tgctcatctt caggtggaac 2050

 taatctggtt aagattccta cagaaaaaag aactcggaga aaactaatgc 2100

 catctccctt gaaaggacag catactctaa agtctccacc atctcaaagt 2150

 gtgcagctca atgattctct tagcaaagaa cttcagccta ttgtatatac 2200

 accagaagac tgtagaaaag cttttcaaaa tccgtctaca gtaaccttaa 2250

 tgaaaccatc atcatttact acaagttttc aggctatcag ctcaaacata 2300

 aacagtgata attgtctgaa aatgttgtgt gaagtagcta tccctcataa 2350

 tagaagaaaa gaatgtggac aggaggactt ggactctaca tttactatat 2400

 gtgaagacat caagagctcg aagtgtaaat tacccgaaca agaatcacta 2450

 ccaaatgata acaaagacat tttacaacgg cttgatcctt cttcattctc 2500

 aactaagcat tctatgcctg taccaagcat ggtgccatcc tacatggcaa 2550

 tgactactgc tgccaaaagg aaacggaaat taacaagttc tacatcaaac 2600

 agttcgttaa ctgcagacgt aaattctgga tttgccaaac gtgttcgaca 2650

 agataattca agtgagaagc acttacaaga aaacaaacca acaatggaac 2700

 ataaaagaaa catctgtaaa ataaatccaa gcatggttag aaaatttgga 2750

 agaaatattt caaaaggaaa tctaagataa atcacttcaa aaccaagcaa 2800

 aatgaagttg atcaaatctg cttttcaaag tttatccaat accctttcaa 2850

 aaatatattt aaaatctttg aaagaagacc catcttaaag ctaagtttac 2900

 ccaagtactt tcagcaagca gaaaaatgaa actctttgtt ttcttctttt 2950

 gtgttctaaa aaaataaaat ttcaaaagaa aaggttgtct tttaagtttt 3000

 ttaaatattt gttgcctttt aaaatccctg agtgtaagtt accatggtgg 3050

 cagcttagtt ttactatgcc acaacaagtt gactaggaca ttttagtaaa 3100

 tggtagtgag ttaaattatc tttattattt tttaaaaata agaatttaga 3150

 agtggtaaaa ttatggccca agatgtattt ggttctctat tatgttttga 3200

 tacattattt taatcatata tatgactttc cttttcaaaa atactttaat 3250

 gtacaagtgt aaatatatgt gcccataaaa tcattgtaaa tattatttag 3300

 tcatcacaaa taaaatattg tcccttgcta cttgatatat taaagatgta 3350

 gattttaaag tgaaaaaaaa aaaaaaaaa 3379

<210> 3594
<211> 898
<212> PRT
<213> Homo sapien

<400> 3594
 Met Ser Val Thr Glu Glu Asp Leu Cys His His Met Lys Val Val
   1               5                  10                  15

 Val Arg Val Arg Pro Glu Asn Thr Lys Glu Lys Ala Ala Gly Phe
                  20                  25                  30

 His Lys Val Val His Val Val Asp Lys His Ile Leu Val Phe Asp
                  35                  40                  45

 Pro Lys Gln Glu Glu Val Ser Phe Phe His Gly Lys Lys Thr Thr
                  50                  55                  60

 Asn Gln Asn Val Ile Lys Lys Gln Asn Lys Asp Leu Lys Phe Val
                  65                  70                  75

 Phe Asp Ala Val Phe Asp Glu Thr Ser Thr Gln Ser Glu Val Phe
                  80                  85                  90

 Glu His Thr Thr Lys Pro Ile Leu Arg Ser Phe Leu Asn Gly Tyr
                  95                 100                 105

 Asn Cys Thr Val Leu Ala Tyr Gly Ala Thr Gly Ala Gly Lys Thr
                 110                 115                 120

 His Thr Met Leu Gly Ser Ala Asp Glu Pro Gly Val Met Tyr Leu
                 125                 130                 135

 Thr Met Leu His Leu Tyr Lys Cys Met Asp Glu Ile Lys Glu Glu
                 140                 145                 150

 Lys Ile Cys Ser Thr Ala Val Ser Tyr Leu Glu Val Tyr Asn Glu
                 155                 160                 165

 Gln Ile Arg Asp Leu Leu Val Asn Ser Gly Pro Leu Ala Val Arg
                 170                 175                 180

 Glu Asp Thr Gln Lys Gly Val Val Val His Gly Leu Thr Leu His
                 185                 190                 195

 Gln Pro Lys Ser Ser Glu Glu Ile Leu His Leu Leu Asp Asn Gly
                 200                 205                 210

 Asn Lys Asn Arg Thr Gln His Pro Thr Asp Met Asn Ala Thr Ser
                 215                 220                 225

 Ser Arg Ser His Ala Val Phe Gln Ile Tyr Leu Arg Gln Gln Asp
                 230                 235                 240

 Lys Thr Ala Ser Ile Asn Gln Asn Val Arg Ile Ala Lys Met Ser
                 245                 250                 255

 Leu Ile Asp Leu Ala Gly Ser Glu Arg Ala Ser Thr Ser Gly Ala
                 260                 265                 270

 Lys Gly Thr Arg Phe Val Glu Gly Thr Asn Ile Asn Arg Ser Leu
                 275                 280                 285

 Leu Ala Leu Gly Asn Val Ile Asn Ala Leu Ala Asp Ser Lys Arg
                 290                 295                 300

 Lys Asn Gln His Ile Pro Tyr Arg Asn Ser Lys Leu Thr Arg Leu
                 305                 310                 315

 Leu Lys Asp Ser Leu Gly Gly Asn Cys Gln Thr Ile Met Ile Ala
                 320                 325                 330

 Ala Val Ser Pro Ser Ser Val Phe Tyr Asp Asp Thr Tyr Asn Thr
                 335                 340                 345

 Leu Lys Tyr Ala Asn Arg Ala Lys Asp Ile Lys Ser Ser Leu Lys
                 350                 355                 360

 Ser Asn Val Leu Asn Val Asn Asn His Ile Thr Gln Tyr Val Lys
                 365                 370                 375

 Ile Cys Asn Glu Gln Lys Ala Glu Ile Leu Leu Leu Lys Glu Lys
                 380                 385                 390

 Leu Lys Ala Tyr Glu Glu Gln Lys Ala Phe Thr Asn Glu Asn Asp
                 395                 400                 405

 Gln Ala Lys Leu Met Ile Ser Asn Pro Gln Glu Lys Glu Ile Glu
                 410                 415                 420

 Arg Phe Gln Glu Ile Leu Asn Cys Leu Phe Gln Asn Arg Glu Glu
                 425                 430                 435

 Ile Arg Gln Glu Tyr Leu Lys Leu Glu Met Leu Leu Lys Glu Asn
                 440                 445                 450

 Glu Leu Lys Ser Phe Tyr Gln Gln Gln Cys His Lys Gln Ile Glu
                 455                 460                 465

 Met Met Cys Ser Glu Asp Lys Val Glu Lys Ala Thr Gly Lys Arg
                 470                 475                 480

 Asp His Arg Leu Ala Met Leu Lys Thr Arg Arg Ser Tyr Leu Glu
                 485                 490                 495

 Lys Arg Arg Glu Glu Glu Leu Lys Gln Phe Asp Glu Asn Thr Asn
                 500                 505                 510

 Trp Leu His Arg Val Glu Lys Glu Met Gly Leu Leu Ser Gln Asn
                 515                 520                 525

 Gly His Ile Pro Lys Glu Leu Lys Lys Asp Leu His Cys His His
                 530                 535                 540

 Leu His Leu Gln Asn Lys Asp Leu Lys Ala Gln Ile Arg His Met
                 545                 550                 555

 Met Asp Leu Ala Cys Leu Gln Glu Gln Gln His Arg Gln Thr Glu
                 560                 565                 570

 Ala Val Leu Asn Ala Leu Leu Pro Thr Leu Arg Lys Gln Tyr Cys
                 575                 580                 585

 Thr Leu Lys Glu Ala Gly Leu Ser Asn Ala Ala Phe Glu Ser Asp
                 590                 595                 600

 Phe Lys Glu Ile Glu His Leu Val Glu Arg Lys Lys Val Val Val
                 605                 610                 615

 Trp Ala Asp Gln Thr Gly Glu Gln Pro Lys Gln Asn Asp Leu Pro
                 620                 625                 630

 Gly Ile Ser Val Leu Met Thr Phe Ser Gln Leu Gly Pro Val Gln
                 635                 640                 645

 Pro Ile Pro Cys Cys Ser Ser Ser Gly Gly Thr Asn Leu Val Lys
                 650                 655                 660

 Ile Pro Thr Glu Lys Arg Thr Arg Arg Lys Leu Met Pro Ser Pro
                 665                 670                 675

 Leu Lys Gly Gln His Thr Leu Lys Ser Pro Pro Ser Gln Ser Val
                 680                 685                 690

 Gln Leu Asn Asp Ser Leu Ser Lys Glu Leu Gln Pro Ile Val Tyr
                 695                 700                 705

 Thr Pro Glu Asp Cys Arg Lys Ala Phe Gln Asn Pro Ser Thr Val
                 710                 715                 720

 Thr Leu Met Lys Pro Ser Ser Phe Thr Thr Ser Phe Gln Ala Ile
                 725                 730                 735

 Ser Ser Asn Ile Asn Ser Asp Asn Cys Leu Lys Met Leu Cys Glu
                 740                 745                 750

 Val Ala Ile Pro His Asn Arg Arg Lys Glu Cys Gly Gln Glu Asp
                 755                 760                 765

 Leu Asp Ser Thr Phe Thr Ile Cys Glu Asp Ile Lys Ser Ser Lys
                 770                 775                 780

 Cys Lys Leu Pro Glu Gln Glu Ser Leu Pro Asn Asp Asn Lys Asp
                 785                 790                 795

 Ile Leu Gln Arg Leu Asp Pro Ser Ser Phe Ser Thr Lys His Ser
                 800                 805                 810

 Met Pro Val Pro Ser Met Val Pro Ser Tyr Met Ala Met Thr Thr
                 815                 820                 825

 Ala Ala Lys Arg Lys Arg Lys Leu Thr Ser Ser Thr Ser Asn Ser
                 830                 835                 840

 Ser Leu Thr Ala Asp Val Asn Ser Gly Phe Ala Lys Arg Val Arg
                 845                 850                 855

 Gln Asp Asn Ser Ser Glu Lys His Leu Gln Glu Asn Lys Pro Thr
                 860                 865                 870

 Met Glu His Lys Arg Asn Ile Cys Lys Ile Asn Pro Ser Met Val
                 875                 880                 885

 Arg Lys Phe Gly Arg Asn Ile Ser Lys Gly Asn Leu Arg
                 890                 895

<210> 3595
<211> 1397
<212> DNA
<213> Homo sapien

<400> 3595
 ggctgctgtc tggggcggta gctggggggg cgctctcccc cctgcccgcg 50

 actcggagca cccccacccc tcccctgccg ggccaggccg ggcggcgttg 100

 ttggcggggg ccccggtgga ggcccggcct gggcggcgcc cgccatgaat 150

 gggctgtcgc tgagtgagct ctgctgcctc ttctgctgcc cgccctgccc 200

 cggccgcatc gctgccaagc tcgccttcct gccgccggag gccacctact 250

 ccctggtgcc tgagcccgag ccggggcctg gtggggccgg ggccgccccc 300

 ttggggaccc tgagagcctc ctcgggcgca cccgggcgct ggaagctgca 350

 cctgacggag cgtgccgact tccagtacag ccagcgcgag ctggacacca 400

 tcgaggtctt ccccaccaag agcgcccgcg gcaaccacgt ctcctgcatg 450

 tatgttcgct gcgtgcctgg tgccaggtac acggtcctct tctcgcacgg 500

 caatgccgtg gacctgggcc agatgagcag cttctacatt ggcctgggct 550

 cccgcctcca ctgcaacatc ttctcctacg actactccgg ctacggtgcc 600

 agctcgggca ggccttccga gaggaacctc tatgccgaca tcgacgccgc 650

 ctggcaggcc ctgcgcacca ggtacggcat cagcccggac agcatcatcc 700

 tgtacgggca gagcatcggc acggtgccca ccgtggacct ggcctcgcgc 750

 tacgagtgtg ccgcggtggt gctgcactcg ccgctcacct cgggcatgcg 800

 cgtcgccttc cccgacacca agaagaccta ctgcttcgac gccttcccta 850

 agtgagcggc ccgggcgggg acgggggcgg ggcggggccc gggccgggcg 900

 cgaagtctca ccggctccac gaccctcccg cagcatcgag aaggtgtcca 950

 agatcacgtc tcccgtgctc atcatccacg gcacggagga cgaggtgatc 1000

 gacttctcgc acgggctggc gctctacgag cgctgcccca aggcggtgga 1050

 gccgctgtgg gtggagggcg ccgggcacaa cgacatcgag ctctacagcc 1100

 agtacctgga gcgcctgcgt cgcttcatct cccaggagct gcccagccag 1150

 cgcgcctagc ggcggcccca accggccgga cctcagcaat aaggcggccc 1200

 ccggacctca ccccgcgccg gcccccaccc aggggctgca tgtggacccc 1250

 ccgggcggcc caggggaccc cgccccgacc caggggctgt ggacgatgta 1300

 caggcaacag agctacgcac tcctttcctt ttggaagcaa gaagaaaata 1350

 cgtgaaaacg gaaattaaag atttaaaatt ttaaaaaaaa aaaaaaa 1397

<210> 3596
<211> 236
<212> PRT
<213> Homo sapien

<400> 3596
 Met Asn Gly Leu Ser Leu Ser Glu Leu Cys Cys Leu Phe Cys Cys
   1               5                  10                  15

 Pro Pro Cys Pro Gly Arg Ile Ala Ala Lys Leu Ala Phe Leu Pro
                  20                  25                  30

 Pro Glu Ala Thr Tyr Ser Leu Val Pro Glu Pro Glu Pro Gly Pro
                  35                  40                  45

 Gly Gly Ala Gly Ala Ala Pro Leu Gly Thr Leu Arg Ala Ser Ser
                  50                  55                  60

 Gly Ala Pro Gly Arg Trp Lys Leu His Leu Thr Glu Arg Ala Asp
                  65                  70                  75

 Phe Gln Tyr Ser Gln Arg Glu Leu Asp Thr Ile Glu Val Phe Pro
                  80                  85                  90

 Thr Lys Ser Ala Arg Gly Asn His Val Ser Cys Met Tyr Val Arg
                  95                 100                 105

 Cys Val Pro Gly Ala Arg Tyr Thr Val Leu Phe Ser His Gly Asn
                 110                 115                 120

 Ala Val Asp Leu Gly Gln Met Ser Ser Phe Tyr Ile Gly Leu Gly
                 125                 130                 135

 Ser Arg Leu His Cys Asn Ile Phe Ser Tyr Asp Tyr Ser Gly Tyr
                 140                 145                 150

 Gly Ala Ser Ser Gly Arg Pro Ser Glu Arg Asn Leu Tyr Ala Asp
                 155                 160                 165

 Ile Asp Ala Ala Trp Gln Ala Leu Arg Thr Arg Tyr Gly Ile Ser
                 170                 175                 180

 Pro Asp Ser Ile Ile Leu Tyr Gly Gln Ser Ile Gly Thr Val Pro
                 185                 190                 195

 Thr Val Asp Leu Ala Ser Arg Tyr Glu Cys Ala Ala Val Val Leu
                 200                 205                 210

 His Ser Pro Leu Thr Ser Gly Met Arg Val Ala Phe Pro Asp Thr
                 215                 220                 225

 Lys Lys Thr Tyr Cys Phe Asp Ala Phe Pro Lys
                 230                 235

<210> 3597
<211> 642
<212> DNA
<213> Homo sapien

<400> 3597
 gctgaagtga aaacgagacc aaggtctagc tctactgttg gtacttatga 50

 gatccagtcc tggcaacatg gagaggattg tcatctgtct gatggtcatc 100

 ttcttgggga cactggtcca caaatcaagc tcccaaggtc aagatcgcca 150

 catgattaga atgcgtcaac ttatagatat tgttgatcag ctgaaaaatt 200

 atgtgaatga cttggtccct gaatttctgc cagctccaga agatgtagag 250

 acaaactgtg agtggtcagc tttttcctgt tttcagaagg cccaactaaa 300

 gtcagcaaat acaggaaaca atgaaaggat aatcaatgta tcaattaaaa 350

 agctgaagag gaaaccacct tccacaaatg cagggagaag acagaaacac 400

 agactaacat gcccttcatg tgattcttat gagaaaaaac cacccaaaga 450

 attcctagaa agattcaaat cacttctcca aaagatgatt catcagcatc 500

 tgtcctctag aacacacgga agtgaagatt cctgaggatc taacttgcag 550

 ttggacacta tgttacatac tctaatatag tagtgaaagt catttctttg 600

 tattccaagt ggaggagccc tattaaatta tataaagaaa ta 642

<210> 3598
<211> 162
<212> PRT
<213> Homo sapien

<400> 3598
 Met Arg Ser Ser Pro Gly Asn Met Glu Arg Ile Val Ile Cys Leu
   1               5                  10                  15

 Met Val Ile Phe Leu Gly Thr Leu Val His Lys Ser Ser Ser Gln
                  20                  25                  30

 Gly Gln Asp Arg His Met Ile Arg Met Arg Gln Leu Ile Asp Ile
                  35                  40                  45

 Val Asp Gln Leu Lys Asn Tyr Val Asn Asp Leu Val Pro Glu Phe
                  50                  55                  60

 Leu Pro Ala Pro Glu Asp Val Glu Thr Asn Cys Glu Trp Ser Ala
                  65                  70                  75

 Phe Ser Cys Phe Gln Lys Ala Gln Leu Lys Ser Ala Asn Thr Gly
                  80                  85                  90

 Asn Asn Glu Arg Ile Ile Asn Val Ser Ile Lys Lys Leu Lys Arg
                  95                 100                 105

 Lys Pro Pro Ser Thr Asn Ala Gly Arg Arg Gln Lys His Arg Leu
                 110                 115                 120

 Thr Cys Pro Ser Cys Asp Ser Tyr Glu Lys Lys Pro Pro Lys Glu
                 125                 130                 135

 Phe Leu Glu Arg Phe Lys Ser Leu Leu Gln Lys Met Ile His Gln
                 140                 145                 150

 His Leu Ser Ser Arg Thr His Gly Ser Glu Asp Ser
                 155                 160

<210> 3599
<211> 2025
<212> DNA
<213> Homo sapien

<400> 3599
 cttctgtgtg tgcacatgtg taatacatat ctgggatcaa agctatctat 50

 ataaagtcct tgattctgtg tgggttcaaa cacatttcaa agcttcagga 100

 tcctgaaagg ttttgctcta cttcctgaag acctgaacac cgctcccata 150

 aagccatggc ttgccttgga tttcagcggc acaaggctca gctgaacctg 200

 gctaccagga cctggccctg cactctcctg ttttttcttc tcttcatccc 250

 tgtcttctgc aaagcaatgc acgtggccca gcctgctgtg gtactggcca 300

 gcagccgagg catcgccagc tttgtgtgtg agtatgcatc tccaggcaaa 350

 gccactgagg tccgggtgac agtgcttcgg caggctgaca gccaggtgac 400

 tgaagtctgt gcggcaacct acatgatggg gaatgagttg accttcctag 450

 atgattccat ctgcacgggc acctccagtg gaaatcaagt gaacctcact 500

 atccaaggac tgagggccat ggacacggga ctctacatct gcaaggtgga 550

 gctcatgtac ccaccgccat actacctggg cataggcaac ggaacccaga 600

 tttatgtaat tgatccagaa ccgtgcccag attctgactt cctcctctgg 650

 atccttgcag cagttagttc ggggttgttt ttttatagct ttctcctcac 700

 agctgtttct ttgagcaaaa tgctaaagaa aagaagccct cttacaacag 750

 gggtctatgt gaaaatgccc ccaacagagc cagaatgtga aaagcaattt 800

 cagccttatt ttattcccat caattgagaa accattatga agaagagagt 850

 ccatatttca atttccaaga gctgaggcaa ttctaacttt tttgctatcc 900

 agctattttt atttgtttgt gcatttgggg ggaattcatc tctctttaat 950

 ataaagttgg atgcggaacc caaattacgt gtactacaat ttaaagcaaa 1000

 ggagtagaaa gacagagctg ggatgtttct gtcacatcag ctccactttc 1050

 agtgaaagca tcacttggga ttaatatggg gatgcagcat tatgatgtgg 1100

 gtcaaggaat taagttaggg aatggcacag cccaaagaag gaaaaggcag 1150

 ggagcgaggg agaagactat attgtacaca ccttatattt acgtatgaga 1200

 cgtttatagc cgaaatgatc ttttcaagtt aaattttatg ccttttattt 1250

 cttaaacaaa tgtatgatta catcaaggct tcaaaaatac tcacatggct 1300

 atgttttagc cagtgatgct aaaggttgta ttgcatatat acatatatat 1350

 atatatatat atatatatat atatatatat atatatatat tttaatttga 1400

 tagtattgtg catagagcca cgtatgtttt tgtgtatttg ttaatggttt 1450

 gaatataaac actatatggc agtgtctttc caccttgggt cccagggaag 1500

 ttttgtggag gagctcagga cactaataca ccaggtagaa cacaaggtca 1550

 tttgctaact agcttggaaa ctggatgagg tcatagcagt gcttgattgc 1600

 gtggaattgt gctgagttgg tgttgacatg tgctttgggg cttttacacc 1650

 agttcctttc aatggtttgc aaggaagcca cagctggtgg tatctgagtt 1700

 gacttgacag aacactgtct tgaagacaat ggcttactcc aggagaccca 1750

 caggtatgac cttctaggaa gctccagttc gatgggccca attcttacaa 1800

 acatgtggtt aatgccatgg acagaagaag gcagcaggtg gcagaatggg 1850

 gtgcatgaag gtttctgaaa attaacactg cttgtgtttt taactcaata 1900

 ttttccatga aaatgcaaca acatgtataa tatttttaat taaataaaaa 1950

 tctgtggtgg tcgttttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2000

 aaaaaaaaaa aaaaaaaaaa aaaaa 2025

<210> 3600
<211> 223
<212> PRT
<213> Homo sapien

<400> 3600
 Met Ala Cys Leu Gly Phe Gln Arg His Lys Ala Gln Leu Asn Leu
   1               5                  10                  15

 Ala Thr Arg Thr Trp Pro Cys Thr Leu Leu Phe Phe Leu Leu Phe
                  20                  25                  30

 Ile Pro Val Phe Cys Lys Ala Met His Val Ala Gln Pro Ala Val
                  35                  40                  45

 Val Leu Ala Ser Ser Arg Gly Ile Ala Ser Phe Val Cys Glu Tyr
                  50                  55                  60

 Ala Ser Pro Gly Lys Ala Thr Glu Val Arg Val Thr Val Leu Arg
                  65                  70                  75

 Gln Ala Asp Ser Gln Val Thr Glu Val Cys Ala Ala Thr Tyr Met
                  80                  85                  90

 Met Gly Asn Glu Leu Thr Phe Leu Asp Asp Ser Ile Cys Thr Gly
                  95                 100                 105

 Thr Ser Ser Gly Asn Gln Val Asn Leu Thr Ile Gln Gly Leu Arg
                 110                 115                 120

 Ala Met Asp Thr Gly Leu Tyr Ile Cys Lys Val Glu Leu Met Tyr
                 125                 130                 135

 Pro Pro Pro Tyr Tyr Leu Gly Ile Gly Asn Gly Thr Gln Ile Tyr
                 140                 145                 150

 Val Ile Asp Pro Glu Pro Cys Pro Asp Ser Asp Phe Leu Leu Trp
                 155                 160                 165

 Ile Leu Ala Ala Val Ser Ser Gly Leu Phe Phe Tyr Ser Phe Leu
                 170                 175                 180

 Leu Thr Ala Val Ser Leu Ser Lys Met Leu Lys Lys Arg Ser Pro
                 185                 190                 195

 Leu Thr Thr Gly Val Tyr Val Lys Met Pro Pro Thr Glu Pro Glu
                 200                 205                 210

 Cys Glu Lys Gln Phe Gln Pro Tyr Phe Ile Pro Ile Asn
                 215                 220

<210> 3601
<211> 1632
<212> DNA
<213> Homo sapien

<400> 3601
 atagatacta gattgtattg aattctgttt taattattct ctaggtaagt 50

 atgttttagg attaaatacc ttttacagat actgaaagtg cctccttttg 100

 tggtgtaaaa aacaaattat ggtgcaaaaa gtaatcacta gattgaaata 150

 catgaaggtt ttttgctttt tgacatacga aaatgtcaag agaaaggcca 200

 aagatttgta ctttttcact tacaaagcac tcctttttcc cttaaacttc 250

 tttctgtcaa attagattta atgagagagt actattttta aggagctatc 300

 tgtttatgta gaatgatttt gttaagagta atgtaaacta ttattgagta 350

 gaggcctaaa gaggactgtg ccatttttgc tatttaaagg aatcacaaat 400

 gatcatactt aagtgagcaa aaatgacaag ttttactagc taagtagaga 450

 aataaatctc aaatgcagcg ctacaatttt cattatctta agtacattgt 500

 acatttctac agaacctgtg attattctcg catgataagg atggtacttg 550

 catatggtga attactactg ttgacagttt ccgcagaaat cctatttcag 600

 tggaccaaca ttgtggcatg gcagcaaatg ccaacatttt gtggaatagc 650

 agcaaatcta caagagaccc tggttggttt ttcgttttgt tttctttgtt 700

 ttttccccct tctcctgaat cagcagggat ggaaggaggg tagggaagtt 750

 atgaattact ccttccagta gtagctctga agtgtcacat ttaatatcag 800

 ttttttttaa acatgattct agttaaatgt agaagagaga agaaagagga 850

 agtgttcact tttttaatac actgatttag aaatttgatg tcttatatca 900

 gtagttctga ggtattgata gcttgcttta tttctgcctt tacgttgaca 950

 gtgttgaagc agggtgaata actagggcat atattttttt ttttttttgt 1000

 aagctgtttc atgatgtttt ctttggaatt tccggataag ttcaggaaaa 1050

 cattctgcat gttgtatcta gtctgatgta cttatccatc tcattacaaa 1100

 caaaaacaca cagaactgca tttgtagctc tgtaatcctt gaatacggaa 1150

 gtaaattttc ttctttcctg actttgacat tgtagctata ctgtttccat 1200

 ttttgttttt acaaatcctt tgggtctaat tctgtgagcc tacctatagc 1250

 actggattaa aatgtctgca tcatttcttt agttatccag ttaactttaa 1300

 aactgttgta aaagtgtaaa ccagcccatg acaggttttt gtacatgtta 1350

 aagaacttca ttgttcagtt ttcatgatta ttgtgtaagg aagactgatg 1400

 tagatgttct gtgctgtcct ggaccatgtt aattacactt acgacgtatt 1450

 ttagttccac atcacaatga tttgtcccca gtgacccttt tatcctttct 1500

 aggcacattt cttgttgttg ttgttgttgc agttcccctt tgcattgtat 1550

 tgctttgaca actgtaattt gaatcagatc tgaaagaggt ccagaataaa 1600

 atatattttg atattaaaaa aagaaaaaaa at 1632

<210> 3602
<211> 102
<212> PRT
<213> Homo sapien

<400> 3602
 Met Gln Arg Tyr Asn Phe His Tyr Leu Lys Tyr Ile Val His Phe
   1               5                  10                  15

 Tyr Arg Thr Cys Asp Tyr Ser Arg Met Ile Arg Met Val Leu Ala
                  20                  25                  30

 Tyr Gly Glu Leu Leu Leu Leu Thr Val Ser Ala Glu Ile Leu Phe
                  35                  40                  45

 Gln Trp Thr Asn Ile Val Ala Trp Gln Gln Met Pro Thr Phe Cys
                  50                  55                  60

 Gly Ile Ala Ala Asn Leu Gln Glu Thr Leu Val Gly Phe Ser Phe
                  65                  70                  75

 Cys Phe Leu Cys Phe Phe Pro Leu Leu Leu Asn Gln Gln Gly Trp
                  80                  85                  90

 Lys Glu Gly Arg Glu Val Met Asn Tyr Ser Phe Gln
                  95                 100

<210> 3603
<211> 442
<212> DNA
<213> Homo sapien

<400> 3603
 ggccattatg gccggggaag gtgctttagt ctgaagatgg cggcctcagc 50

 agcgcgaggt gctgcggcgc tgcgtagaag tatcaatcag ccggttgctt 100

 ttgtgagaag aattccttgg actgcggcgt cgagtcagct gaaagaacac 150

 tttgcacagt tcggccatgt cagaaggtgc attttacctt ttgacaagga 200

 gactggcttt cacagaggtt tgggttgggt tcagttttct tcagaagaag 250

 gacttcggaa tgcactacaa caggaaaatc atattataga tggagtaaag 300

 gtccaggttc acactagaag gccaaaactt ccgcaaacat ctgatgatga 350

 aaagaaagat ttttgagact gcagcctatt aataaagtta acataactga 400

 gaaaaaaaaa aaaaacaaaa aaaaaaaaaa aaaaaaaaaa aa 442

<210> 3604
<211> 109
<212> PRT
<213> Homo sapien

<400> 3604
 Met Ala Ala Ser Ala Ala Arg Gly Ala Ala Ala Leu Arg Arg Ser
   1               5                  10                  15

 Ile Asn Gln Pro Val Ala Phe Val Arg Arg Ile Pro Trp Thr Ala
                  20                  25                  30

 Ala Ser Ser Gln Leu Lys Glu His Phe Ala Gln Phe Gly His Val
                  35                  40                  45

 Arg Arg Cys Ile Leu Pro Phe Asp Lys Glu Thr Gly Phe His Arg
                  50                  55                  60

 Gly Leu Gly Trp Val Gln Phe Ser Ser Glu Glu Gly Leu Arg Asn
                  65                  70                  75

 Ala Leu Gln Gln Glu Asn His Ile Ile Asp Gly Val Lys Val Gln
                  80                  85                  90

 Val His Thr Arg Arg Pro Lys Leu Pro Gln Thr Ser Asp Asp Glu
                  95                 100                 105

 Lys Lys Asp Phe


<210> 3605
<211> 3330
<212> DNA
<213> Homo sapien

<400> 3605
 gcatccgtgc gtctgtggaa ggctgcgttt ccggcctgag aaaccgtcat 50

 gtttctgggg agtcacctca gctggcagtt accaccgtgt tagaaagcag 100

 cctcaggacc ggccacctcc atcactggcg tcaccatggg ggctgtgctg 150

 ggtgtcttct ccctcgccag ctgggttcca tgcctctgca gcggtgcctc 200

 atgtttgctg tgtagttgct gtcctaacag taagaattcc acggtgactc 250

 gcctcattta tgctttcatt ctcctcctga gcactgtcgt atcctatatc 300

 atgcagagaa aagagatgga aacttacttg aagaagattc ctggattttg 350

 tgaaggggga tttaaaatcc atgaggctga tataaatgca gataaagatt 400

 gtgatgtgct ggttggttat aaagctgtgt atcggatcag ctttgccatg 450

 gccatctttt tctttgtctt ttctctgctc atgttcaaag taaaaacaag 500

 taaagatctc cgagcggcag tacacaatgg gttttggttc ttcaaaattg 550

 ctgcccttat tggaatcatg gttggctctt tctacatccc tgggggctat 600

 ttcagctcag tctggtttgt tgttggcatg ataggggccg ccctcttcat 650

 cctcattcag ctggtgctgc tggtagattt tgctcattct tggaatgaat 700

 catgggtaaa tcgaatggaa gaaggaaacc caaggttgtg gtatgctgct 750

 ttactgtctt tcacaagcgc cttttatatc ctgtcaatca tctgtgtcgg 800

 gctgctctat acatattaca ccaaaccaga tggctgcaca gaaaacaagt 850

 tcttcatcag tattaacctg atcctttgcg ttgtggcttc tattatatcg 900

 atccacccaa aaattcagga acaccagcct cgctccggcc tcttgcagtc 950

 ctccctcatc accctctaca ctatgtacct cacctggtca gccatgtcca 1000

 atgaacctga tcgttcctgc aatcccaacc tgatgagctt tattacacgc 1050

 ataactgcac caaccctggc tcctggaaat tcaactgctg tggtccctac 1100

 ccctactcca ccatcaaaga gtgggtcttt actggattca gataatttta 1150

 ttggactgtt tgtctttgtt ctctgcctct tgtattctag catccgcact 1200

 tccactaata gccaagtaga caagctgacc ctgtcaggga gtgacagcgt 1250

 catccttggt gatacaacta ccagtggtgc cagtgatgaa gaagatggac 1300

 agcctcggcg ggctgtggac aacgagaaag agggagtgca gtatagctac 1350

 tccttattcc acctcatgct ctgcttggct tccttgtaca tcatgatgac 1400

 cctgaccagc tggtacagcc ctgatgcaaa gtttcagagc atgaccagca 1450

 agtggccagc tgtgtgggtc aagatcagct ccagctgggt ctgcctcctg 1500

 ctttacgtct ggacccttgt ggctccactt gtcctcacca gtcgggactt 1550

 cagctgaacc tctgagtgcc aaggacacca ctggaactca caaaggtctc 1600

 cttcaccgaa aacccatata ccttttaagt ttgtttcaac taaaatatta 1650

 agtgaatgct ttgcaagttt gactgtatgc aggtttatat cagaaggtga 1700

 gattgaataa tgcttgatgc agaatcgaaa cttctcattt atctgtatat 1750

 tatgtttact tctaaggata tagcacaaag ggaacatttt ttgtttaaag 1800

 tgaactacag ctgtgctgtg aagagagttc tttataaagc ctgtaggttc 1850

 ttttaacttt ggtttaaaat gtaagatagg aaaatgttgg atatttgagg 1900

 ccatgcttaa tatatttata ttgcagtatc ctttaaaagc aaaaaaaaaa 1950

 aaatgcattt atattacagt tttcctctat gaaagtcctt acttatatga 2000

 tacaagcact gtgttttgtg cttaaactct tcagcggggt agcatcaaag 2050

 ttcttgggga aggatcgtat atgtgggtcc cttccctaga agaatggttg 2100

 ctgatatggc tactgcttct acatcttgag ttttttaatt tacttttttt 2150

 acactgtagc attgagactg cttgattcaa gtctggtgct ttgccagatg 2200

 tattaatttc cataaatgct ttgtgagttt ggttaaaatg aagattcact 2250

 tgggaaaaca ctgcagcttt agtctgtgtt actatcttgt tatgagtatg 2300

 taaaagtaaa atgcatgtga atttatcata tttgcactat gaaggtattt 2350

 ggttaaaata caaagacttt taagatttta aggccctttc ttccaacagc 2400

 ttttatagtt agcagccatt ctttattttc tggatagcca ggttttatca 2450

 cgcttctagt caggatgctc ctattccttc taaaaattac ggtctgacta 2500

 gtgagcaaag tcttgaattt attcaaaagt cctaaatacc ttctctaggt 2550

 aagacacttg gtagatgaga gacggaaggc attgtcaaga accattttca 2600

 tgagaggtgg tgtgcaaaaa ggtagaataa aagagttctt tcaacaaaga 2650

 tttactgtct attctgtact agaccctgta ggttttgggg tacagtgtta 2700

 aacatgatag aggctctgcc gtcttggact ttaatagctt agagaagaga 2750

 gcaaatgagc tgacaggtgg ttataatgtg aattagtgct gtggtttagg 2800

 aattggagag aactcaaagg agaggtattt ggtgtaatgg taggctttct 2850

 ggagaaaatg atatttaagc caagaactct tagaagttag ctaagagaga 2900

 gatgggaaaa tgagacgaca ttgctggagt agataaaact gcatgttaaa 2950

 ggcaggaaga tggggaaaaa aagttcagta aagctggaat ggggaaatgt 3000

 agtcagggac tgaattttaa agggctttat caacctcagt aaagagtttg 3050

 gaccttatgt tgagggtggc tgaaaacata ttcatagtgt catgaacaaa 3100

 ttttatcttc agtcacttgg gctgatatat agagaatgga tttagagaga 3150

 tgagaccagg tgcagtccat atgagatgtg aaatagagaa gtggaatcgt 3200

 agggacgggg agaaattgac aggtgagggc tacttagcaa ttagaatttt 3250

 ttttcagtcc accctcaaca taaggtccaa actctttact gaggttgata 3300

 aagcccttta aaattcagta cctgactaca 3330

<210> 3606
<211> 473
<212> PRT
<213> Homo sapien

<400> 3606
 Met Gly Ala Val Leu Gly Val Phe Ser Leu Ala Ser Trp Val Pro
   1               5                  10                  15

 Cys Leu Cys Ser Gly Ala Ser Cys Leu Leu Cys Ser Cys Cys Pro
                  20                  25                  30

 Asn Ser Lys Asn Ser Thr Val Thr Arg Leu Ile Tyr Ala Phe Ile
                  35                  40                  45

 Leu Leu Leu Ser Thr Val Val Ser Tyr Ile Met Gln Arg Lys Glu
                  50                  55                  60

 Met Glu Thr Tyr Leu Lys Lys Ile Pro Gly Phe Cys Glu Gly Gly
                  65                  70                  75

 Phe Lys Ile His Glu Ala Asp Ile Asn Ala Asp Lys Asp Cys Asp
                  80                  85                  90

 Val Leu Val Gly Tyr Lys Ala Val Tyr Arg Ile Ser Phe Ala Met
                  95                 100                 105

 Ala Ile Phe Phe Phe Val Phe Ser Leu Leu Met Phe Lys Val Lys
                 110                 115                 120

 Thr Ser Lys Asp Leu Arg Ala Ala Val His Asn Gly Phe Trp Phe
                 125                 130                 135

 Phe Lys Ile Ala Ala Leu Ile Gly Ile Met Val Gly Ser Phe Tyr
                 140                 145                 150

 Ile Pro Gly Gly Tyr Phe Ser Ser Val Trp Phe Val Val Gly Met
                 155                 160                 165

 Ile Gly Ala Ala Leu Phe Ile Leu Ile Gln Leu Val Leu Leu Val
                 170                 175                 180

 Asp Phe Ala His Ser Trp Asn Glu Ser Trp Val Asn Arg Met Glu
                 185                 190                 195

 Glu Gly Asn Pro Arg Leu Trp Tyr Ala Ala Leu Leu Ser Phe Thr
                 200                 205                 210

 Ser Ala Phe Tyr Ile Leu Ser Ile Ile Cys Val Gly Leu Leu Tyr
                 215                 220                 225

 Thr Tyr Tyr Thr Lys Pro Asp Gly Cys Thr Glu Asn Lys Phe Phe
                 230                 235                 240

 Ile Ser Ile Asn Leu Ile Leu Cys Val Val Ala Ser Ile Ile Ser
                 245                 250                 255

 Ile His Pro Lys Ile Gln Glu His Gln Pro Arg Ser Gly Leu Leu
                 260                 265                 270

 Gln Ser Ser Leu Ile Thr Leu Tyr Thr Met Tyr Leu Thr Trp Ser
                 275                 280                 285

 Ala Met Ser Asn Glu Pro Asp Arg Ser Cys Asn Pro Asn Leu Met
                 290                 295                 300

 Ser Phe Ile Thr Arg Ile Thr Ala Pro Thr Leu Ala Pro Gly Asn
                 305                 310                 315

 Ser Thr Ala Val Val Pro Thr Pro Thr Pro Pro Ser Lys Ser Gly
                 320                 325                 330

 Ser Leu Leu Asp Ser Asp Asn Phe Ile Gly Leu Phe Val Phe Val
                 335                 340                 345

 Leu Cys Leu Leu Tyr Ser Ser Ile Arg Thr Ser Thr Asn Ser Gln
                 350                 355                 360

 Val Asp Lys Leu Thr Leu Ser Gly Ser Asp Ser Val Ile Leu Gly
                 365                 370                 375

 Asp Thr Thr Thr Ser Gly Ala Ser Asp Glu Glu Asp Gly Gln Pro
                 380                 385                 390

 Arg Arg Ala Val Asp Asn Glu Lys Glu Gly Val Gln Tyr Ser Tyr
                 395                 400                 405

 Ser Leu Phe His Leu Met Leu Cys Leu Ala Ser Leu Tyr Ile Met
                 410                 415                 420

 Met Thr Leu Thr Ser Trp Tyr Ser Pro Asp Ala Lys Phe Gln Ser
                 425                 430                 435

 Met Thr Ser Lys Trp Pro Ala Val Trp Val Lys Ile Ser Ser Ser
                 440                 445                 450

 Trp Val Cys Leu Leu Leu Tyr Val Trp Thr Leu Val Ala Pro Leu
                 455                 460                 465

 Val Leu Thr Ser Arg Asp Phe Ser
                 470

<210> 3607
<211> 2018
<212> DNA
<213> Rattus norvegicus

<400> 3607
 cctttccgtc tggcggcagc catcaggtaa gccaagatgg gtgcatacaa 50

 gtacatccag gagctatgga gaaagaagca gtctgatgtc atgcgctttc 100

 ttctgagggt ccgctgctgg cagtaccgcc agctctctgc tctccacagg 150

 gctccccgcc ccacccggcc tgataaagcg cgccgactgg gctacaaggc 200

 caagcaaggt tacgttatat ataggattcg tgttcgccgt ggtggccgaa 250

 aacgcccagt tcctaagggt gcaacttacg gcaagcctgt ccatcatggt 300

 gttaaccagc taaagtttgc tcgaagcctt cagtccgttg cagaggagcg 350

 agctggacgc cactgtgggg ctctgagagt cctgaattct tactgggttg 400

 gtgaagattc cacatacaaa ttttttgagg ttatcctcat tgatccattc 450

 cataaagcta tcagaagaaa tcctgacacc cagtggatca ccaaaccagt 500

 ccacaagcac agggagatgc gtgggctgac atctgcaggc cgaaagagcc 550

 gtggccttgg aaagggccac aagttccacc acactattgg tggctctcgc 600

 cgggcagctt ggagaaggcg caatactctc cagctccacc gttaccgcta 650

 atataagtaa agtttgtaaa attcatactt aataaacaat ttaggacagt 700

 catgtctgct tacaggtgtt atttgtctgt taaaactagt ctgcagatgt 750

 ttcttgaatg ctttgtcaaa ttaagaaagt taaagtgcaa taatgtttga 800

 agacaataag tggtggtgta tcttgtttct aataagataa acttttttgt 850

 ctttgcttta tcttattagg gagttgtatg tcagtgtata aaacatactg 900

 tgtggtataa caggcttaat aaattcttta aaaggagaga actgaaacta 950

 gccctgtaga tttgtctggt gcatgtgatg aaacctgcag ctttatcgga 1000

 gtgatggcaa tgctctgctg gtttattttc aagtggctgc gtttttttta 1050

 gtttggcagg tgtagacttt ttaagttggg ctttagaaaa tctgggttag 1100

 cctgaagaaa attgcctcag cctccacagt accattttaa attcacataa 1150

 aaggtgaaag ctcctggttc agtgccatgg cttcatggca ttcagtgatt 1200

 agtggtaatg gtaaacactg gtgtgttttg aagttgaatg tgcgataaaa 1250

 ttattagcct taagattggt aagctagcaa tgaatgctag ggtgggaagc 1300

 tggtgagcca gtggccatta gataaatacc tttcaagtgt gagcttagac 1350

 gtcaacccta aaatacttaa ccgtaatgct aattgtgatc attatgaatc 1400

 ccttcagtca cattaggggg aaagtagttg gctataagta cgtcattctt 1450

 agtccagtca gtcttaaaaa catcttgggt tacccactct gtccactccc 1500

 ataggctaca gaaaaagtca caagcgcatg gtttccaacc atatgtgttt 1550

 tctgcagtta tttctcttgt tctggccaaa caaccctaaa aatccttacc 1600

 attccacaaa gttggaccat cacttgtgca cccactttga ctatgagtat 1650

 accaccacat tgcatttctg tttgcaccat gtcttccagg agactagact 1700

 actgttgtcc agggtcaatt tgagtgtaaa gaaaatgtag acaaggaatt 1750

 gcccaatttt aaattctgac tttgctgact taatttaaat gctcgttctg 1800

 aaccaatttt ctcctatctt ctctaggggt ttcaaaagac tcagttaatt 1850

 gatttccagg aagtactcat agcaagttca taaaagttct tgagacctaa 1900

 atttcttcac aaaaaaagaa aagatcttaa gtcatacatt ttaattgtgt 1950

 agaggttgtt caactgaagg aataaatgtc tattaaacta aaaaaaaaaa 2000

 aaaaaaaaaa aaaaaaaa 2018

<210> 3608
<211> 204
<212> PRT
<213> Rattus norvegicus

<400> 3608
 Met Gly Ala Tyr Lys Tyr Ile Gln Glu Leu Trp Arg Lys Lys Gln
   1               5                  10                  15

 Ser Asp Val Met Arg Phe Leu Leu Arg Val Arg Cys Trp Gln Tyr
                  20                  25                  30

 Arg Gln Leu Ser Ala Leu His Arg Ala Pro Arg Pro Thr Arg Pro
                  35                  40                  45

 Asp Lys Ala Arg Arg Leu Gly Tyr Lys Ala Lys Gln Gly Tyr Val
                  50                  55                  60

 Ile Tyr Arg Ile Arg Val Arg Arg Gly Gly Arg Lys Arg Pro Val
                  65                  70                  75

 Pro Lys Gly Ala Thr Tyr Gly Lys Pro Val His His Gly Val Asn
                  80                  85                  90

 Gln Leu Lys Phe Ala Arg Ser Leu Gln Ser Val Ala Glu Glu Arg
                  95                 100                 105

 Ala Gly Arg His Cys Gly Ala Leu Arg Val Leu Asn Ser Tyr Trp
                 110                 115                 120

 Val Gly Glu Asp Ser Thr Tyr Lys Phe Phe Glu Val Ile Leu Ile
                 125                 130                 135

 Asp Pro Phe His Lys Ala Ile Arg Arg Asn Pro Asp Thr Gln Trp
                 140                 145                 150

 Ile Thr Lys Pro Val His Lys His Arg Glu Met Arg Gly Leu Thr
                 155                 160                 165

 Ser Ala Gly Arg Lys Ser Arg Gly Leu Gly Lys Gly His Lys Phe
                 170                 175                 180

 His His Thr Ile Gly Gly Ser Arg Arg Ala Ala Trp Arg Arg Arg
                 185                 190                 195

 Asn Thr Leu Gln Leu His Arg Tyr Arg
                 200

<210> 3609
<211> 1337
<212> DNA
<213> Homo sapien

<400> 3609
 gcggcggact cggcttgttg tgttgctgcc tgagtgccgg agacggtcct 50

 gctgctgccg cagtcctgcc agctgtccga cgatgtcgtc ccacctagtc 100

 gagccgccgc cgcccctgca caacaacaac aacaactgcg aggaaaatga 150

 gcagtctctg cccccgccgg ccggcctcaa cagttcctgg gtggagctac 200

 ccatgaacag cagcaatggc aatgataatg gcaatgggaa aaatgggggg 250

 ctggaacacg taccatcctc atcctccatc cacaatggag acatggagaa 300

 gattcttttg gatgcacaac atgaatcagg acagagtagt tccagaggca 350

 gttctcactg tgacagccct tcgccacaag aagatgggca gatcatgttt 400

 gatgtggaaa tgcacaccag cagggaccat agctctcagt cagaagaaga 450

 agttgtagaa ggagagaagg aagtcgaggc tttgaagaaa agtgcggact 500

 gggtatcaga ctggtccagt agacccgaaa acattccacc caaggagttc 550

 cacttcagac accctaaacg ttctgtgtct ttaagcatga ggaaaagtgg 600

 agccatgaag aaagggggta ttttctccgc agaatttctg aaggtgttca 650

 ttccatctct cttcctttct catgttttgg ctttggggct aggcatctat 700

 attggaaagc gactgagcac accctctgcc agcacctact gagggaaagg 750

 aaaagcccct ggaaatgcgt gtgacctgtg aagtggtgta ttgtcacagt 800

 agcttatttg aacttgagac cattgtaagc atgacccaac ctaccaccct 850

 gtttttacat atccaattcc agtaaccctc aaattcaata ttttattcaa 900

 actctgttga ggcattttac taaccttata ccctttttgg cctgaagaca 950

 ttttagaatt tcctaacaga gtttactgtt gtttagaaat ttgcaagggc 1000

 ttcttttccg caaatgccac cagcagatta taattttgtc ggcaatgcta 1050

 ttatctctaa ttagtgccac cagactagac ctgtatcatt catggtataa 1100

 attttactct tccaacataa ctaccatctc tctcttaaaa cgagatcagg 1150

 ttagcaaatg atgtaaaaga agctttattg tctagttgtt ttttttcccc 1200

 caagacaaag gcaagtttcc ctaagtttga gttgatagtt attaaaaaga 1250

 aaacaaaaca aaaaaaaaag gcaaggcaca acaaaaaaat atcctgggca 1300

 ataaaaaaaa tattttaaac caaaaaaaaa aaaaaaa 1337

<210> 3610
<211> 219
<212> PRT
<213> Homo sapien

<400> 3610
 Met Ser Ser His Leu Val Glu Pro Pro Pro Pro Leu His Asn Asn
   1               5                  10                  15

 Asn Asn Asn Cys Glu Glu Asn Glu Gln Ser Leu Pro Pro Pro Ala
                  20                  25                  30

 Gly Leu Asn Ser Ser Trp Val Glu Leu Pro Met Asn Ser Ser Asn
                  35                  40                  45

 Gly Asn Asp Asn Gly Asn Gly Lys Asn Gly Gly Leu Glu His Val
                  50                  55                  60

 Pro Ser Ser Ser Ser Ile His Asn Gly Asp Met Glu Lys Ile Leu
                  65                  70                  75

 Leu Asp Ala Gln His Glu Ser Gly Gln Ser Ser Ser Arg Gly Ser
                  80                  85                  90

 Ser His Cys Asp Ser Pro Ser Pro Gln Glu Asp Gly Gln Ile Met
                  95                 100                 105

 Phe Asp Val Glu Met His Thr Ser Arg Asp His Ser Ser Gln Ser
                 110                 115                 120

 Glu Glu Glu Val Val Glu Gly Glu Lys Glu Val Glu Ala Leu Lys
                 125                 130                 135

 Lys Ser Ala Asp Trp Val Ser Asp Trp Ser Ser Arg Pro Glu Asn
                 140                 145                 150

 Ile Pro Pro Lys Glu Phe His Phe Arg His Pro Lys Arg Ser Val
                 155                 160                 165

 Ser Leu Ser Met Arg Lys Ser Gly Ala Met Lys Lys Gly Gly Ile
                 170                 175                 180

 Phe Ser Ala Glu Phe Leu Lys Val Phe Ile Pro Ser Leu Phe Leu
                 185                 190                 195

 Ser His Val Leu Ala Leu Gly Leu Gly Ile Tyr Ile Gly Lys Arg
                 200                 205                 210

 Leu Ser Thr Pro Ser Ala Ser Thr Tyr
                 215

<210> 3611
<211> 4646
<212> DNA
<213> Homo sapien

<400> 3611
 gggaggcggt ggccgaggcc caggcggtgg cggcggcggc ccaggaggcg 50

 gcggacgggg agctgcggga gcaggcccgg gcctggctct ctagcggccg 100

 cctggctgca gcatgcgcgc ccgccggggg ctgctgcggc tgccgcgccg 150

 ctcgctgctc gccgcgctct tcttcttttc tctctcgtcc tcgctgctgt 200

 acttcgtcta tgtggcgccc ggcatagtga acacctacct cttcatgatg 250

 caagcccaag gcattctgat ccgggacaac gtgagaacaa tcggtgctca 300

 ggtttatgag caggtgcttc ggagtgctta tgccaagagg aacagcagtg 350

 taaatgactc agattatcct cttgacttga accacagtga aaccttcctg 400

 caaactacaa catttcttcc tgaagacttc acctactttg caaaccatac 450

 ctgccctgaa agactccctt ccatgaaggg cccaatagac ataaacatga 500

 gtgaaattgg aatggattac attcatgaac tcttctccaa agacccaacc 550

 atcaagctcg gaggtcactg gaagccttct gattgcatgc ctcggtggaa 600

 ggtggcgatc cttatcccct tccggaaccg ccacgagcac ctcccagtcc 650

 tgttcagaca cctgcttccc atgctccagc gccagcgctt gcagtttgca 700

 ttttatgtgg ttgaacaagt tggtacccaa ccctttaatc gagccatgct 750

 tttcaacgtt ggctttcaag aggcaatgaa agacttggat tgggactgtt 800

 tgatttttca tgatgtagat cacataccgg aaagtgatcg caactattat 850

 ggatgtggac agatgccgag gcattttgca accaaattgg ataagtatat 900

 gtatctgctt ccttataccg agttctttgg cggagtgagt ggcttaacag 950

 tggaacaatt tcggaaaatc aatggctttc ctaatgcttt ctggggttgg 1000

 ggtggagaag atgacgacct ctggaacaga gtacagaatg caggctattc 1050

 tgtgagccgg ccagagggtg acacaggaaa gtacaagtcc attcctcatc 1100

 accatcgagg agaagtccag tttcttggaa ggtatgctct gctgaggaag 1150

 tcaaaagaac ggcaagggct ggatggcctc aacaacctga actactttgc 1200

 aaacatcaca tacgacgcct tgtataaaaa cataactgtc aacctgacac 1250

 ccgagctggc tcaggtgaac gagtactgag aggagagaat gtacgtttgc 1300

 tttacccacc gccaccaaga aagcagtccg atgagatttt tttttggagg 1350

 ggggagggtc tacacagcaa gagaacagaa atactgtgtc tcatgaagga 1400

 tcacagagtt cagggggaaa atgtgacagc acacgcacaa acgccttcac 1450

 tggatcagcc gctggaactg agggagtgag cttggggact tccttcgtca 1500

 gcactggctt tctgttttca caagacagac gtctgtcccg ctgctctctc 1550

 cccatctcct accccacatc ctgtcttagc cgcagtctcc agaacccatg 1600

 atgaactgtg atctgccgtg gtcctgccgt ggtcctgccg tggagcctgt 1650

 ccctacacat gaccttggag cctcttggcc ttcagagcag aggcaaaccc 1700

 accacagggc agctgcgttt taggaagagc aaatgaaact ccacaccatt 1750

 cttctagatc tctggtgttc tctttggttt cattttttta aaaaattacc 1800

 ttctttgggt ggggattgag ggtggagggg agggtgtttg ggaaagataa 1850

 atagacataa atatataaca atcacttctt gaagaagtat aattgtaaat 1900

 aagccatgta aaatgccttt ttaaaattta attttctagc tggctccaat 1950

 tcaaattgag gatttatgta ttaggccact tacttggttg gcaagtgcag 2000

 gaactcagtt aaaatgcagt tgaagaatgt catctcccga attgctgtca 2050

 ctttggcgag ggagtggata tagggcatgt cacaaaagaa caaaataacc 2100

 cgacctttat tgctgggagc tggcttctgt ccctttcttc ccccccccac 2150

 gagtcttgcc cttgacttct gctctggatt cactcttccc tgtcggccgc 2200

 gcatgtgctc atcccactct ccgctaagcg ggaggctgct gttagagcag 2250

 gctgcttcct gcctaaagca ggcccttcgg ggctcgctgc acacacatct 2300

 ctggctctcc aggcttcgtg ttctgtcttt tcatcagcat ggcggggcgg 2350

 ggggcggggg gcgggggtgt gtatgggaat ccctccccct cttacttttt 2400

 ctcttgtgga acttggccac agtttctgaa caatgtgcct acattaccag 2450

 ctggcttcag tgattcctct gtgtcccttt ttggtttctg gaaagattct 2500

 ttgtcaacat tagtaactga tacatagaac caaggagcac tcaaataggg 2550

 agccaggagc cagggagctg gtgacacttg tgtgctgtgg ggcagctggg 2600

 atccaggtaa gaccggattg aagctttgaa attagactaa caaagctcca 2650

 gacagcaaga gcccaggtgc actgctcaca cccccacctg cattttgaag 2700

 tcatattatt ttttgttttg ttttttaaga cggtctggct ctgtcgccta 2750

 agctggagtg tggtggcacg atcacagctc actgcagcct ccatctccta 2800

 ggctcaagcc attttcccac ctcagcctcc cgagtagctg ggactacagg 2850

 tgcacaccac cacacctggc taattttttg tatttttagt agagacaggg 2900

 gtttcttcca tgttgcccag gctggtctcg aactcctgga ctcaagcaat 2950

 ccgcccacct tgacttccca aagtgctggg attatgggcg ggtgtgagcc 3000

 attgcgccca gccttgaagt catgttctaa attgtatttg aatttgtgcc 3050

 tctttgtttt tccccaaacc aaagccctca aattgtagtc tctgtcggct 3100

 tctgcagaat tctggaaaat gccagttttc ctcccccgcc cttgttttcc 3150

 ataaaacata tttatatatt gtgatgagga gtactttctg aagagtactt 3200

 cgtatttttt tttaattgcc ttgtttgcct tcaacttcct tgattttcat 3250

 agtttacatg ggtgtgtgta ggggtgtgtg tgtgtatgtg tgtgggttag 3300

 ggcttttttc gttgcatgtg atggttctgt ggacatatga tccccacaaa 3350

 ctgtgggagt gattggccag gccttgtttt gtttgtttgt ttgtttgtgt 3400

 ttttgttctt ttgaagaata gagtggtatt tagaaaataa attgcattgc 3450

 aaagctctta tcggctcata tgagagagca ggttcctgcc cttgaaaatg 3500

 ccggtaagct atagcatatg ttttttaaga cttaagcatt tcatgcttta 3550

 aaataccttc acaagtgaac attacacaca gaagttcatt tggttttcct 3600

 ttgttttatg gtgcatatag caataaagac ccccctccac cctgcaaccc 3650

 ccatccccca ccgggccttt gtccctgcct tggcttttct ccccttctca 3700

 ttctcctctc ccctttcctc actgaaggct gtgagttgct ttcaatgtga 3750

 caacactatg atgtcatttg gaaggatttg ccaggacaga ctgattctga 3800

 gtcctgggtg ccgtatgtgt atgcggcagt gttgtcaggc gatcttgttt 3850

 gaagctctat gttgccataa ttaccatcaa gtacacactg ttggcaaaag 3900

 gctaacacct gactttagaa aatgctgatt tgagaacaaa aggaaaggtc 3950

 ttttttcact gcttaaagtg gggtcacttt gatacctttg cggtcatgtc 4000

 tgtgtctgat gagtgtagaa tctctggatg tgcactgtca gtcatgtgtc 4050

 caccaggcct cgaatatcat atgggaaatg tcatagttaa aaacgtacag 4100

 ccaggcccgt gtgctgttaa tagtgtgaaa ttgtcatgtt aaaaaaaaaa 4150

 acaggaacca aatgtgacct tgtgcatata ttggtagctg aaaatcttca 4200

 aggctactga tgggtggccc cttaatcttg tctttgattg ctgtgtgcag 4250

 ggaaaggtgt ccccgtttgt tcatgctgtt ttggggggtg ggggggtatt 4300

 tgcaagaata ctcattttga cataataggt cctcttgtca gagatcctct 4350

 accacagaca ttaatagctg agcaggagcc acatggattg attgtatcca 4400

 ctcaccattg acgatggcat tgagcgtagc tagcttattt ccatcactac 4450

 gtgtttttga gcttgctctt acgttttaag aggtgccagg ggtacatttt 4500

 tgcactgaaa tctaaagatg ttttaaaaaa cacttttcac aaaaatagtc 4550

 ctttgtcatt acattattta ctcatgtgtt tgtacatttt tgtatgttaa 4600

 tttatgaatg attttttcag taaaaaatac atattcaaga accaaa 4646

<210> 3612
<211> 388
<212> PRT
<213> Homo sapien

<400> 3612
 Met Arg Ala Arg Arg Gly Leu Leu Arg Leu Pro Arg Arg Ser Leu
   1               5                  10                  15

 Leu Ala Ala Leu Phe Phe Phe Ser Leu Ser Ser Ser Leu Leu Tyr
                  20                  25                  30

 Phe Val Tyr Val Ala Pro Gly Ile Val Asn Thr Tyr Leu Phe Met
                  35                  40                  45

 Met Gln Ala Gln Gly Ile Leu Ile Arg Asp Asn Val Arg Thr Ile
                  50                  55                  60

 Gly Ala Gln Val Tyr Glu Gln Val Leu Arg Ser Ala Tyr Ala Lys
                  65                  70                  75

 Arg Asn Ser Ser Val Asn Asp Ser Asp Tyr Pro Leu Asp Leu Asn
                  80                  85                  90

 His Ser Glu Thr Phe Leu Gln Thr Thr Thr Phe Leu Pro Glu Asp
                  95                 100                 105

 Phe Thr Tyr Phe Ala Asn His Thr Cys Pro Glu Arg Leu Pro Ser
                 110                 115                 120

 Met Lys Gly Pro Ile Asp Ile Asn Met Ser Glu Ile Gly Met Asp
                 125                 130                 135

 Tyr Ile His Glu Leu Phe Ser Lys Asp Pro Thr Ile Lys Leu Gly
                 140                 145                 150

 Gly His Trp Lys Pro Ser Asp Cys Met Pro Arg Trp Lys Val Ala
                 155                 160                 165

 Ile Leu Ile Pro Phe Arg Asn Arg His Glu His Leu Pro Val Leu
                 170                 175                 180

 Phe Arg His Leu Leu Pro Met Leu Gln Arg Gln Arg Leu Gln Phe
                 185                 190                 195

 Ala Phe Tyr Val Val Glu Gln Val Gly Thr Gln Pro Phe Asn Arg
                 200                 205                 210

 Ala Met Leu Phe Asn Val Gly Phe Gln Glu Ala Met Lys Asp Leu
                 215                 220                 225

 Asp Trp Asp Cys Leu Ile Phe His Asp Val Asp His Ile Pro Glu
                 230                 235                 240

 Ser Asp Arg Asn Tyr Tyr Gly Cys Gly Gln Met Pro Arg His Phe
                 245                 250                 255

 Ala Thr Lys Leu Asp Lys Tyr Met Tyr Leu Leu Pro Tyr Thr Glu
                 260                 265                 270

 Phe Phe Gly Gly Val Ser Gly Leu Thr Val Glu Gln Phe Arg Lys
                 275                 280                 285

 Ile Asn Gly Phe Pro Asn Ala Phe Trp Gly Trp Gly Gly Glu Asp
                 290                 295                 300

 Asp Asp Leu Trp Asn Arg Val Gln Asn Ala Gly Tyr Ser Val Ser
                 305                 310                 315

 Arg Pro Glu Gly Asp Thr Gly Lys Tyr Lys Ser Ile Pro His His
                 320                 325                 330

 His Arg Gly Glu Val Gln Phe Leu Gly Arg Tyr Ala Leu Leu Arg
                 335                 340                 345

 Lys Ser Lys Glu Arg Gln Gly Leu Asp Gly Leu Asn Asn Leu Asn
                 350                 355                 360

 Tyr Phe Ala Asn Ile Thr Tyr Asp Ala Leu Tyr Lys Asn Ile Thr
                 365                 370                 375

 Val Asn Leu Thr Pro Glu Leu Ala Gln Val Asn Glu Tyr
                 380                 385

<210> 3613
<211> 2307
<212> DNA
<213> Homo sapien

<400> 3613
 gtgactgtgg agtttgaatt gggtggcggt tgactgtaga gccgctctct 50

 ctcactggca cagcgaggtt ttgctcagcc cttgtctcgg gaccgcagcc 100

 tccgccgagc gccatggctc ctaggaaggg cagtagtcgg gtggccaaga 150

 ccaactcctt acggaggcgg aagctcgcct cctttctgaa agacttcgac 200

 cgtgaagtgg aaatacgaat caagcaaatt gagtcagaca ggcagaacct 250

 cctcaaggag gtggataacc tctacaacat cgagatcctg cggctcccca 300

 aggctctgcg cgagatgaac tggcttgact acttcgccct tggaggaaac 350

 aaacaggccc tggaagaggc ggcaacagct gacctggata tcaccgaaat 400

 aaacaaacta acagcagaag ctattcagac acccctgaaa tctgccaaaa 450

 cacgaaaggt aatacaggta gatgaaatga tagtggaaga ggaagaagaa 500

 gaagaaaatg aacgtaagaa tcttcaaact gcaagagtca aaaggtgtcc 550

 tccatccaag aagagaactc agtccataca aggaaaagga aaagggaaaa 600

 ggtcaagccg tgctaacact gttaccccag ccgtgggccg attggaggtg 650

 tccatggtca aaccaactcc aggcctgaca cccaggtttg actcaagggt 700

 cttcaagacc cctggcctgc gtactccagc agcaggagag cggatttaca 750

 acatctcagg gaatggcagc cctcttgctg acagcaaaga gatcttcctc 800

 actgtgccag tgggcggcgg agagagcctg cgattattgg ccagtgactt 850

 gcagaggcac agtattgccc agctggatcc agaggccttg ggaaacatta 900

 agaagctctc caaccgtctc gcccaaatct gcagcagcat acggacccac 950

 aaatgagaca ccaaagttga caggatggac ttttaatggg cacttctggg 1000

 accctgaaga gacttcttcc cttcaggctt attgtttgag tgtgaagttc 1050

 cagagcaagg agccatgttc ctctaaggga attcaggaat tcagacgtgc 1100

 tagtcccaca ccagttaggt agagctgtct gttcaccctc ccatcccagc 1150

 tgatcccagt cactgcttgc tggggccatg ccatggaagc ttcccatcag 1200

 tctcccagct gaatcctccc tgctctctga gctgctgcct tttgcctcct 1250

 gcaactcaac atcctcttca ccctgccctg cctgcagttg agggggcgaa 1300

 gaagaaccct gtgttctcag gaagactgcc tccaccaccg ctacccagag 1350

 aacctctgca tctggcattt ctgctctcta tgcttgagac cgggaggttt 1400

 aggctcagat aagtgagctc tgggccatga gagggtaggt ccagaaggtg 1450

 gggggaactg tacagatcag cagagcagga cagttggcag cagtgacctc 1500

 agtagggaac atgtccgtct accctctcgc actcatgaca cctcccccta 1550

 ccagccctcc tcttcctcct cctcctcctc ctgtgggagg tggtcagtgg 1600

 gacttaggga tctttcacct gctgtgccca gtagttctga agtctgcttg 1650

 tggagcagtg ttttatgttt atccctgttt actgaagacc aaatactggt 1700

 ttggagacaa cttccatgtc ttgctcttct acctccctag ttagtggaaa 1750

 tttggataag ggaactgtag ggcccagatt ctggaggttt tatgtcattg 1800

 gccacagaat aactgtctct aagctatcca tggtccagtg gtccctgcca 1850

 agtctgtaga cttcagagag cacttctctc ttatggggtt catgggaaca 1900

 ggggcgggtg tgacttgctt ggtggcctca ttccatgtgt gcctgtgcct 1950

 ggggcatgga ctttgttaag cagagtcagc agtgaggtcc tcattctcca 2000

 gccagcctct ctgccctgga gaatcatgtg ctatgttcta agaatttgag 2050

 aactagagtc ctcatcccca ggcttgaagg cacatggctt tctcatgtag 2100

 ggctctctgt ggtatttgtt attattttgc aacaagacca ttttagtaaa 2150

 acagtcctgt tcaagttgta ttcttttaag ttcttttatt ctcctttccc 2200

 tgagattttt gtatatattg ttctgagtaa tggtatcttt gagctgattg 2250

 ttctaatcag agctggtacc tactttcaat aaattctggt tttgtgtttt 2300

 cttctgt 2307

<210> 3614
<211> 280
<212> PRT
<213> Homo sapien

<400> 3614
 Met Ala Pro Arg Lys Gly Ser Ser Arg Val Ala Lys Thr Asn Ser
   1               5                  10                  15

 Leu Arg Arg Arg Lys Leu Ala Ser Phe Leu Lys Asp Phe Asp Arg
                  20                  25                  30

 Glu Val Glu Ile Arg Ile Lys Gln Ile Glu Ser Asp Arg Gln Asn
                  35                  40                  45

 Leu Leu Lys Glu Val Asp Asn Leu Tyr Asn Ile Glu Ile Leu Arg
                  50                  55                  60

 Leu Pro Lys Ala Leu Arg Glu Met Asn Trp Leu Asp Tyr Phe Ala
                  65                  70                  75

 Leu Gly Gly Asn Lys Gln Ala Leu Glu Glu Ala Ala Thr Ala Asp
                  80                  85                  90

 Leu Asp Ile Thr Glu Ile Asn Lys Leu Thr Ala Glu Ala Ile Gln
                  95                 100                 105

 Thr Pro Leu Lys Ser Ala Lys Thr Arg Lys Val Ile Gln Val Asp
                 110                 115                 120

 Glu Met Ile Val Glu Glu Glu Glu Glu Glu Glu Asn Glu Arg Lys
                 125                 130                 135

 Asn Leu Gln Thr Ala Arg Val Lys Arg Cys Pro Pro Ser Lys Lys
                 140                 145                 150

 Arg Thr Gln Ser Ile Gln Gly Lys Gly Lys Gly Lys Arg Ser Ser
                 155                 160                 165

 Arg Ala Asn Thr Val Thr Pro Ala Val Gly Arg Leu Glu Val Ser
                 170                 175                 180

 Met Val Lys Pro Thr Pro Gly Leu Thr Pro Arg Phe Asp Ser Arg
                 185                 190                 195

 Val Phe Lys Thr Pro Gly Leu Arg Thr Pro Ala Ala Gly Glu Arg
                 200                 205                 210

 Ile Tyr Asn Ile Ser Gly Asn Gly Ser Pro Leu Ala Asp Ser Lys
                 215                 220                 225

 Glu Ile Phe Leu Thr Val Pro Val Gly Gly Gly Glu Ser Leu Arg
                 230                 235                 240

 Leu Leu Ala Ser Asp Leu Gln Arg His Ser Ile Ala Gln Leu Asp
                 245                 250                 255

 Pro Glu Ala Leu Gly Asn Ile Lys Lys Leu Ser Asn Arg Leu Ala
                 260                 265                 270

 Gln Ile Cys Ser Ser Ile Arg Thr His Lys
                 275                 280

<210> 3615
<211> 1453
<212> DNA
<213> Homo sapien

<400> 3615
 ggccacgaag gccggccccc accccgggac ccccgccgtc cccgggccgg 50

 ccggccggtg ggcacgatga gccaggtgct ggggaagccg cagccgcagg 100

 acgaggacga cgcggaggag gaggaggagg aggatgagct ggtggggcta 150

 gcggactacg gagacgggcc cgactcctcc gacgccgatc cggacagcgg 200

 cacagaggag ggagttctgg acttcagtga ccccttcagc actgaagtga 250

 agccgagaat cctgctcatg ggcctgagga gaagcggcaa gtcgtctatt 300

 cagaaagttg tctttcacaa aatgtctccc aacgaaactc tgttcttgga 350

 gagcactaat aagatatgcc gggaagatgt ttccaacagc tcctttgtca 400

 attttcagat ttgggacttc ccaggacaga ttgacttttt tgaccctaca 450

 tttgactatg agatgatctt ccggggaaca ggagcactga tatttgtcat 500

 tgactcacag gatgattaca tggaagccct ggccaggctc cacctcacgg 550

 tgaccagggc ctacaaagtg aatactgaca tcaacttcga ggtgtttatt 600

 cataaagtgg atggtctgtc agatgaccac aaaattgaaa cccaaagaga 650

 tattcaccag agggcaaacg atgaccttgc agatgctgga ttagaaaaaa 700

 ttcacctcag cttttatctg acaagcatat atgatcattc aatatttgaa 750

 gcttttagca aagttgttca gaaactgatt ccacaactcc caactctgga 800

 gaatttgctg aacatcttta tctcaaattc tggaattgaa aaggcatttc 850

 tatttgatgt ggtcagtaaa atttatattg caactgatag tactccggtg 900

 gatatgcaaa cctatgagct ctgctgtgat atgatagatg tggttattga 950

 catctcttgt atttatggtc tcaaagaaga tggagcagga accccctatg 1000

 acaaggaatc cacagccatc ataaagctta ataatacaac cgtgctttat 1050

 ttaaaagagg tgacaaagtt cctggctctc gtttgctttg tcagagagga 1100

 aagctttgaa agaaaagggc taattgacta taattttcat tgcttccgga 1150

 aggccattca tgaagttttt gaggtgagaa tgaaagtagt aaaatctcga 1200

 aaggttcaga atcggctgca gaagaaaaag agagccaccc ctaatgggac 1250

 ccctagagtg ctgctgtagg tgaggtttca ggaatgtctt ttgaaatcag 1300

 accttatcca tgaggctgct gcgccatgtt gcactaaagg aagaggaaga 1350

 aggagattgg gacacatacc attgatttgt tgttaaaaaa aaaaaaattc 1400

 ctgcaaccct cttgatcttc tcttttataa ttaaagtcag cacttgaagc 1450

 ggg 1453

<210> 3616
<211> 400
<212> PRT
<213> Homo sapien

<400> 3616
 Met Ser Gln Val Leu Gly Lys Pro Gln Pro Gln Asp Glu Asp Asp
   1               5                  10                  15

 Ala Glu Glu Glu Glu Glu Glu Asp Glu Leu Val Gly Leu Ala Asp
                  20                  25                  30

 Tyr Gly Asp Gly Pro Asp Ser Ser Asp Ala Asp Pro Asp Ser Gly
                  35                  40                  45

 Thr Glu Glu Gly Val Leu Asp Phe Ser Asp Pro Phe Ser Thr Glu
                  50                  55                  60

 Val Lys Pro Arg Ile Leu Leu Met Gly Leu Arg Arg Ser Gly Lys
                  65                  70                  75

 Ser Ser Ile Gln Lys Val Val Phe His Lys Met Ser Pro Asn Glu
                  80                  85                  90

 Thr Leu Phe Leu Glu Ser Thr Asn Lys Ile Cys Arg Glu Asp Val
                  95                 100                 105

 Ser Asn Ser Ser Phe Val Asn Phe Gln Ile Trp Asp Phe Pro Gly
                 110                 115                 120

 Gln Ile Asp Phe Phe Asp Pro Thr Phe Asp Tyr Glu Met Ile Phe
                 125                 130                 135

 Arg Gly Thr Gly Ala Leu Ile Phe Val Ile Asp Ser Gln Asp Asp
                 140                 145                 150

 Tyr Met Glu Ala Leu Ala Arg Leu His Leu Thr Val Thr Arg Ala
                 155                 160                 165

 Tyr Lys Val Asn Thr Asp Ile Asn Phe Glu Val Phe Ile His Lys
                 170                 175                 180

 Val Asp Gly Leu Ser Asp Asp His Lys Ile Glu Thr Gln Arg Asp
                 185                 190                 195

 Ile His Gln Arg Ala Asn Asp Asp Leu Ala Asp Ala Gly Leu Glu
                 200                 205                 210

 Lys Ile His Leu Ser Phe Tyr Leu Thr Ser Ile Tyr Asp His Ser
                 215                 220                 225

 Ile Phe Glu Ala Phe Ser Lys Val Val Gln Lys Leu Ile Pro Gln
                 230                 235                 240

 Leu Pro Thr Leu Glu Asn Leu Leu Asn Ile Phe Ile Ser Asn Ser
                 245                 250                 255

 Gly Ile Glu Lys Ala Phe Leu Phe Asp Val Val Ser Lys Ile Tyr
                 260                 265                 270

 Ile Ala Thr Asp Ser Thr Pro Val Asp Met Gln Thr Tyr Glu Leu
                 275                 280                 285

 Cys Cys Asp Met Ile Asp Val Val Ile Asp Ile Ser Cys Ile Tyr
                 290                 295                 300

 Gly Leu Lys Glu Asp Gly Ala Gly Thr Pro Tyr Asp Lys Glu Ser
                 305                 310                 315

 Thr Ala Ile Ile Lys Leu Asn Asn Thr Thr Val Leu Tyr Leu Lys
                 320                 325                 330

 Glu Val Thr Lys Phe Leu Ala Leu Val Cys Phe Val Arg Glu Glu
                 335                 340                 345

 Ser Phe Glu Arg Lys Gly Leu Ile Asp Tyr Asn Phe His Cys Phe
                 350                 355                 360

 Arg Lys Ala Ile His Glu Val Phe Glu Val Arg Met Lys Val Val
                 365                 370                 375

 Lys Ser Arg Lys Val Gln Asn Arg Leu Gln Lys Lys Lys Arg Ala
                 380                 385                 390

 Thr Pro Asn Gly Thr Pro Arg Val Leu Leu
                 395                 400

<210> 3617
<211> 895
<212> DNA
<213> Homo sapien

<400> 3617
 gcggagcgag gctggaggcg cgggagggca gcgagaggtt cgcgggtgca 50

 gcgcacagga gaccatgtcc gggggcagca gctgcagcca gaccccaagc 100

 cgggccatcc ccgccactcg ccgggtggtg ctcggcgacg gcgtgcagct 150

 cccgcccggg gactacagca cgacccccgg cggcacgctc ttcagcacca 200

 ccccgggagg taccaggatc atctatgacc ggaaattcct gatggagtgt 250

 cggaactcac ctgtgaccaa aacaccccca agggatctgc ccaccattcc 300

 gggggtcacc agcccttcca gtgatgagcc ccccatggaa gccagccaga 350

 gccacctgcg caatagccca gaagataagc gggcgggcgg tgaagagtca 400

 cagtttgaga tggacattta aagcaccagc catcgtgtgg agcactacca 450

 aggggcccct cagggccttc ctgggaggag tcccaccagc caggccttat 500

 gaaagtgatc atactgggca ggcgttggcg tggggtcgga caccccagcc 550

 ctttctccct cactcagggc acctgccccc tcctcttcgt gaacaccagc 600

 agatacctcc ttgtgcctcc actgatgcag gagctgccac cccaagggga 650

 gtgacccctg ccagcacacc ctgcagccaa gggccaggaa gtggacaaga 700

 acgaaccctt ccttccgaat gatcagcagt tccagcccct cgctgctggg 750

 ggcgcaacca ccccttcctt aggttgatgt gcttgggaaa gctccctccc 800

 cctccttccc caagagagga aataaaagcc accttcgccc taggaaaaaa 850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 895

<210> 3618
<211> 118
<212> PRT
<213> Homo sapien

<400> 3618
 Met Ser Gly Gly Ser Ser Cys Ser Gln Thr Pro Ser Arg Ala Ile
   1               5                  10                  15

 Pro Ala Thr Arg Arg Val Val Leu Gly Asp Gly Val Gln Leu Pro
                  20                  25                  30

 Pro Gly Asp Tyr Ser Thr Thr Pro Gly Gly Thr Leu Phe Ser Thr
                  35                  40                  45

 Thr Pro Gly Gly Thr Arg Ile Ile Tyr Asp Arg Lys Phe Leu Met
                  50                  55                  60

 Glu Cys Arg Asn Ser Pro Val Thr Lys Thr Pro Pro Arg Asp Leu
                  65                  70                  75

 Pro Thr Ile Pro Gly Val Thr Ser Pro Ser Ser Asp Glu Pro Pro
                  80                  85                  90

 Met Glu Ala Ser Gln Ser His Leu Arg Asn Ser Pro Glu Asp Lys
                  95                 100                 105

 Arg Ala Gly Gly Glu Glu Ser Gln Phe Glu Met Asp Ile
                 110                 115

<210> 3619
<211> 2121
<212> DNA
<213> Homo sapien

<400> 3619
 ggcacgaggg cccggcggca ggtcccagcc cggggctaga gaccgagggc 50

 cggggtccgg gcccggcggc gggacccagg cggttgaggc tggtcaggag 100

 tcagccagcc tgaaagagca ggatggatct tgatgtggtt aacatgtttg 150

 tgattgcggg cggcacgctg gccatcccaa tcctggcatt tgtggcttca 200

 tttcttctgt ggccttcagc actgataaga atctattatt ggtactggcg 250

 gaggacattg ggcatgcaag tccgctatgt tcaccatgaa gactatcagt 300

 tctgttattc cttccggggc aggcctgggc acaaaccctc catcctcatg 350

 ctccacggat tctctgccca caaggatatg tggctcagtg tggtcaagtt 400

 ccttccaaag aacctgcact tggtctgcgt ggacatgcca ggacatgagg 450

 gcaccacccg ctcctccctg gatgacctgt ccatagatgg gcaagttaag 500

 aggatacacc agtttgtaga atgcctgaag ctgaacaaaa aacctttcca 550

 cctggtaggc acctccatgg gtggccaggt ggctggggtg tatgctgctt 600

 actacccatc ggatgtctcc agcctgtgtc tcgtgtgtcc tgctggcctg 650

 cagtactcaa ctgacaatca atttgtacaa cggctcaaag aactgcaggg 700

 ctctgccgcc gtggagaaga ttcccttgat cccgtctacc ccagaagaga 750

 tgagtgaaat gcttcagctc tgctcctatg tccgcttcaa ggtgccccag 800

 cagatcctgc aaggccttgt cgatgtccgc atccctcata acaacttcta 850

 ccgaaagttg tttttggaaa tcgtcagtga gaagtccaga tactctctcc 900

 atcagaacat ggacaagatc aaggttccga cgcagatcat ctgggggaaa 950

 caagaccagg tgctggatgt gtctggggca gacatgttgg ccaagtcaat 1000

 tgccaactgc caggtggagc ttctggaaaa ctgtgggcac tcagtagtga 1050

 tggaaagacc caggaagaca gccaagctca taatcgactt tttagcttct 1100

 gtgcacaaca cagacaacaa caagaagctg gactgaggcc ccgactgcag 1150

 cctgcattct gcacacagca tctgctccca tcccccaagt ctgacgcagc 1200

 caccactctc agggatcctg ccccaaatgc ggtcggagcg ccagtgaccc 1250

 tgaggaagcc cgtcccttat ccctggtatc cacggttccc cagagctttg 1300

 gggaccacgc gaaaacctcc aagatatttt tcacaaaata gaaactcata 1350

 tggaacaaaa taagaaaccc cagccatgaa atctaccatg aagtcttcaa 1400

 gttcatgtca ctgagaagct tgtgcaaagc agccaccttg gaccataatt 1450

 aaatcaagga cattttcttt gagacattcc ttatagttgg agactcaaga 1500

 tatttttgtt gcatcaggtg tattcccttg catgggcagt ggcttttata 1550

 ggagcattag tcctcattcg ctgaaccctg ttgtttaggt ctaatttaag 1600

 ttttacatag agacccatgt atgactgcag cccattggct gcaagaccag 1650

 ggaggaaagt ggcaagctgt agaaaatgtt tacacgcatg gaggggcatt 1700

 gctctagccc tcagagcgtc cggagcagca gggtacatgg gtgggaggtt 1750

 cattcagcac ccaccagtca ggtatgttct gagtgaaccc acagcagtcg 1800

 cagaatgagc acctggcagg gtgggtttcc taggaataat ttattatttt 1850

 taaaaatagg cctaataaag caataatgtt ctagacatct gtctaagtaa 1900

 tcagactcag gttccacaca caagcaacaa ctcgtgggcc tcttttctat 1950

 ttcaatgtgc tactaagaac ccttggatgt aacatactag ttagttaatg 2000

 aattctgtga attctgtgaa gagtaatgtg attgaaaata agtctaaaca 2050

 gctgtaaaag tgaccacaat gacatgaaat aaatttaata agtctagatc 2100

 agcaaaaaaa aaaaaaaaaa a 2121

<210> 3620
<211> 337
<212> PRT
<213> Homo sapien

<400> 3620
 Met Asp Leu Asp Val Val Asn Met Phe Val Ile Ala Gly Gly Thr
   1               5                  10                  15

 Leu Ala Ile Pro Ile Leu Ala Phe Val Ala Ser Phe Leu Leu Trp
                  20                  25                  30

 Pro Ser Ala Leu Ile Arg Ile Tyr Tyr Trp Tyr Trp Arg Arg Thr
                  35                  40                  45

 Leu Gly Met Gln Val Arg Tyr Val His His Glu Asp Tyr Gln Phe
                  50                  55                  60

 Cys Tyr Ser Phe Arg Gly Arg Pro Gly His Lys Pro Ser Ile Leu
                  65                  70                  75

 Met Leu His Gly Phe Ser Ala His Lys Asp Met Trp Leu Ser Val
                  80                  85                  90

 Val Lys Phe Leu Pro Lys Asn Leu His Leu Val Cys Val Asp Met
                  95                 100                 105

 Pro Gly His Glu Gly Thr Thr Arg Ser Ser Leu Asp Asp Leu Ser
                 110                 115                 120

 Ile Asp Gly Gln Val Lys Arg Ile His Gln Phe Val Glu Cys Leu
                 125                 130                 135

 Lys Leu Asn Lys Lys Pro Phe His Leu Val Gly Thr Ser Met Gly
                 140                 145                 150

 Gly Gln Val Ala Gly Val Tyr Ala Ala Tyr Tyr Pro Ser Asp Val
                 155                 160                 165

 Ser Ser Leu Cys Leu Val Cys Pro Ala Gly Leu Gln Tyr Ser Thr
                 170                 175                 180

 Asp Asn Gln Phe Val Gln Arg Leu Lys Glu Leu Gln Gly Ser Ala
                 185                 190                 195

 Ala Val Glu Lys Ile Pro Leu Ile Pro Ser Thr Pro Glu Glu Met
                 200                 205                 210

 Ser Glu Met Leu Gln Leu Cys Ser Tyr Val Arg Phe Lys Val Pro
                 215                 220                 225

 Gln Gln Ile Leu Gln Gly Leu Val Asp Val Arg Ile Pro His Asn
                 230                 235                 240

 Asn Phe Tyr Arg Lys Leu Phe Leu Glu Ile Val Ser Glu Lys Ser
                 245                 250                 255

 Arg Tyr Ser Leu His Gln Asn Met Asp Lys Ile Lys Val Pro Thr
                 260                 265                 270

 Gln Ile Ile Trp Gly Lys Gln Asp Gln Val Leu Asp Val Ser Gly
                 275                 280                 285

 Ala Asp Met Leu Ala Lys Ser Ile Ala Asn Cys Gln Val Glu Leu
                 290                 295                 300

 Leu Glu Asn Cys Gly His Ser Val Val Met Glu Arg Pro Arg Lys
                 305                 310                 315

 Thr Ala Lys Leu Ile Ile Asp Phe Leu Ala Ser Val His Asn Thr
                 320                 325                 330

 Asp Asn Asn Lys Lys Leu Asp
                 335

<210> 3621
<211> 2241
<212> DNA
<213> Homo sapien

<400> 3621
 tgggacttat agaagggaga ggagcgaaca tggcagcgcg ttggcggttt 50

 tggtgtgtct ctgtgaccat ggtggtggcg ctgctcatcg tttgcgacgt 100

 tccctcagcc tctgcccaaa gaaagaagga gatggtgtta tcagaaaagg 150

 ttagtcagct gatggaatgg actaacaaaa gacctgtaat aagaatgaat 200

 ggagacaagt tccgtcgcct tgtgaaagcc ccaccgagaa attactccgt 250

 tatcgtcatg ttcactgctc tccaactgca tagacagtgt gtcgtttgca 300

 agcaagctga tgaagaattc cagatcctgg caaactcctg gcgatactcc 350

 agtgcattca ccaacaggat attttttgcc atggtggatt ttgatgaagg 400

 ctctgatgta tttcagatgc taaacatgaa ttcagctcca actttcatca 450

 actttcctgc aaaagggaaa cccaaacggg gtgatacata tgagttacag 500

 gtgcggggtt tttcagctga gcagattgcc cggtggatcg ccgacagaac 550

 tgatgtcaat attagagtga ttagaccccc aaattatgct ggtcccctta 600

 tgttgggatt gcttttggct gttattggtg gacttgtgta tcttcgaaga 650

 agtaatatgg aatttctctt taataaaact ggatgggctt ttgcagcttt 700

 gtgttttgtg cttgctatga catctggtca aatgtggaac catataagag 750

 gaccaccata tgcccataag aatccccaca cgggacatgt gaattatatc 800

 catggaagca gtcaagccca gtttgtagct gaaacacaca ttgttcttct 850

 gtttaatggt ggagttacct taggaatggt gcttttgtgt gaagctgcta 900

 cctctgacat ggatattgga aagcgaaaga taatgtgtgt ggctggtatt 950

 ggacttgttg tattattctt cagttggatg ctctctattt ttagatctaa 1000

 atatcatggc tacccataca gctttctgat gagttaaaaa ggtcccagag 1050

 atatatagac actggagtac tggaaattga aaaacgaaaa tcgtgtgtgt 1100

 ttgaaaagaa gaatgcaact tgtatattct gtattacctc tttttttcaa 1150

 gtgatttaaa tagttaatca tttaaccaaa gaagatgtgt agtgccttaa 1200

 caagcaatcc tctgtcaaaa tctgaggtat ttgaaaataa ttatcctctt 1250

 aaccttctct tcccagtgaa ctttatggaa catttaattt agtacaatta 1300

 agtatattat aaaaattgta aaactactac tttgttttag ttagaacaaa 1350

 gctcaaaact actttagtta acttggtcat ctgatcttat attgccttat 1400

 ccaaagatgg ggaaagtaag tcctgaccag gtgttcccac atatgcctgt 1450

 tacagataac tacattagga attcattctt agcttcttca tctttgtgtg 1500

 gatgtgtata ctttacgcat ctttcctttt gagtagagaa attatgtgtg 1550

 tcatgtggtc ttctgaaaat ggaacaccat tcttcagagc acacgtctag 1600

 ccctcagcaa gacagttgtt tctcctcctc cttgcatatt tcctactgcg 1650

 ctccagcctg agtgatagag tgagactctg tctcaaaaaa aaagtatctc 1700

 taaatacagg attataattt ctgcttgagt atggtgttaa ctaccttgta 1750

 tttagaaaga tttcagattc attccatctc cttagttttc ttttaaggtg 1800

 acccatctgt gataaaaata tagcttagtg ctaaaatcag tgtaacttat 1850

 acatggccta aaatgtttct acaaattaga gtttgtcact tattccattt 1900

 gtacctaaga gaaaaatagg ctcagttaga aaaggactcc ctggccaggc 1950

 gcagtgactt acgcctgtaa tctcagcact ttgggaggcc aaggcaggca 2000

 gatcacgagg tcaggagttc gagaccatcc tggccaacat ggtgaaaccc 2050

 cgtctctact aaaaatataa aaattagctg ggtgtggtgg caggagcctg 2100

 taatcccagc tgcacaggag gctgaggcac gagaatcact tgaactcagg 2150

 agatggaggt ttcagtgagc cgagatcacg ccactgcact ccagcctggc 2200

 aacagagcga gactccatct caaaaaaaaa aaaaaaaaaa a 2241

<210> 3622
<211> 335
<212> PRT
<213> Homo sapien

<400> 3622
 Met Ala Ala Arg Trp Arg Phe Trp Cys Val Ser Val Thr Met Val
   1               5                  10                  15

 Val Ala Leu Leu Ile Val Cys Asp Val Pro Ser Ala Ser Ala Gln
                  20                  25                  30

 Arg Lys Lys Glu Met Val Leu Ser Glu Lys Val Ser Gln Leu Met
                  35                  40                  45

 Glu Trp Thr Asn Lys Arg Pro Val Ile Arg Met Asn Gly Asp Lys
                  50                  55                  60

 Phe Arg Arg Leu Val Lys Ala Pro Pro Arg Asn Tyr Ser Val Ile
                  65                  70                  75

 Val Met Phe Thr Ala Leu Gln Leu His Arg Gln Cys Val Val Cys
                  80                  85                  90

 Lys Gln Ala Asp Glu Glu Phe Gln Ile Leu Ala Asn Ser Trp Arg
                  95                 100                 105

 Tyr Ser Ser Ala Phe Thr Asn Arg Ile Phe Phe Ala Met Val Asp
                 110                 115                 120

 Phe Asp Glu Gly Ser Asp Val Phe Gln Met Leu Asn Met Asn Ser
                 125                 130                 135

 Ala Pro Thr Phe Ile Asn Phe Pro Ala Lys Gly Lys Pro Lys Arg
                 140                 145                 150

 Gly Asp Thr Tyr Glu Leu Gln Val Arg Gly Phe Ser Ala Glu Gln
                 155                 160                 165

 Ile Ala Arg Trp Ile Ala Asp Arg Thr Asp Val Asn Ile Arg Val
                 170                 175                 180

 Ile Arg Pro Pro Asn Tyr Ala Gly Pro Leu Met Leu Gly Leu Leu
                 185                 190                 195

 Leu Ala Val Ile Gly Gly Leu Val Tyr Leu Arg Arg Ser Asn Met
                 200                 205                 210

 Glu Phe Leu Phe Asn Lys Thr Gly Trp Ala Phe Ala Ala Leu Cys
                 215                 220                 225

 Phe Val Leu Ala Met Thr Ser Gly Gln Met Trp Asn His Ile Arg
                 230                 235                 240

 Gly Pro Pro Tyr Ala His Lys Asn Pro His Thr Gly His Val Asn
                 245                 250                 255

 Tyr Ile His Gly Ser Ser Gln Ala Gln Phe Val Ala Glu Thr His
                 260                 265                 270

 Ile Val Leu Leu Phe Asn Gly Gly Val Thr Leu Gly Met Val Leu
                 275                 280                 285

 Leu Cys Glu Ala Ala Thr Ser Asp Met Asp Ile Gly Lys Arg Lys
                 290                 295                 300

 Ile Met Cys Val Ala Gly Ile Gly Leu Val Val Leu Phe Phe Ser
                 305                 310                 315

 Trp Met Leu Ser Ile Phe Arg Ser Lys Tyr His Gly Tyr Pro Tyr
                 320                 325                 330

 Ser Phe Leu Met Ser
                 335

<210> 3623
<211> 3084
<212> DNA
<213> Homo sapien

<400> 3623
 aagatctaaa aacggacatc tccaccgtgg gtggctcctt tttctttttc 50

 tttttttccc acccttcagg aagtggacgt ttcgttatct tctgatcctt 100

 gcaccttctt ttggggaaac ggggcccttc tgcccagatc ccctctcttt 150

 tctcggaaaa caaactacta agtcggcatc cggggtaact acagtggaga 200

 gggtttccgc ggagacgcgc cgccggaccc tcctctgcac tttggggagg 250

 cgtgctccct ccagaaccgg cgttctccgc gcgcaaatcc cggcgacgcg 300

 gggtcgcggg gtggccgccg gggcagcctc gtctagcgcg cgccgcgcag 350

 acgcccccgg agtcgccagc taccgcagcc ctcgccgccc agtgcccttc 400

 ggcctcgggg cgggcgcctg cgtcggtctc cgcgaagcgg gaaagcgcgg 450

 cggccgccgg gattcgggcg ccgcggcagc tgctccggct gccggccggc 500

 ggccccgcgc tcgcccgccc cgcttccgcc cgctgtcctg ctgcacgaac 550

 ccttccaact ctcctttcct cccccaccct tgagttaccc ctctgtcttt 600

 cctgctgttg cgcgggtgct cccacagcgg agcggagatt acagagccgc 650

 cgggatgccc caactctccg gaggaggtgg cggcggcggg ggggacccgg 700

 aactctgcgc cacggacgag atgatcccct tcaaggacga gggcgatcct 750

 cagaaggaaa agatcttcgc cgagatcagt catcccgaag aggaaggcga 800

 tttagctgac atcaagtctt ccttggtgaa cgagtctgaa atcatcccgg 850

 ccagcaacgg acacgaggtg gccagacaag cacaaacctc tcaggagccc 900

 taccacgaca aggccagaga acaccccgat gacggaaagc atccagatgg 950

 aggcctctac aacaagggac cctcctactc gagttattcc gggtacataa 1000

 tgatgccaaa tatgaataac gacccataca tgtcaaatgg atctctttct 1050

 ccacccatcc cgagaacatc aaataaagtg cccgtggtgc agccatccca 1100

 tgcggtccat cctctcaccc ccctcatcac ttacagtgac gagcactttt 1150

 ctccaggatc acacccgtca cacatcccat cagatgtcaa ctccaaacaa 1200

 ggcatgtcca gacatcctcc agctcctgat atccctactt tttatccctt 1250

 gtctccgggt ggtgttggac agatcacccc acctcttggc tggcaaggtc 1300

 agcctgtata tcccatcacg ggtggattca ggcaacccta cccatcctca 1350

 ctgtcagtcg acacttccat gtccaggttt tcccatcata tgattcccgg 1400

 tcctcctggt ccccacacaa ctggcatccc tcatccagct attgtaacac 1450

 ctcaggtcaa acaggaacat ccccacactg acagtgacct aatgcacgtg 1500

 aagcctcagc atgaacagag aaaggagcag gagccaaaaa gacctcacat 1550

 taagaagcct ctgaatgctt ttatgttata catgaaagaa atgagagcga 1600

 atgtcgttgc tgagtgtact ctaaaagaaa gtgcagctat caaccagatt 1650

 cttggcagaa ggtggcatgc cctctcccgt gaagagcagg ctaaatatta 1700

 tgaattagca cggaaagaaa gacagctaca tatgcagctt tatccaggct 1750

 ggtctgcaag agacaattat ggtaagaaaa agaagaggaa gagagagaaa 1800

 ctacaggaat ctgcatcagg tacaggtcca agaatgacag ctgcctacat 1850

 ctgaaacatg gtggaaaacg aagctcattc ccaacgtgca aagccaaggc 1900

 agcgacccca ggacctcttc tggagatgga agcttgttga aaacccagac 1950

 tgtctccacg gcctgcccag tcgacgccaa aggaacactg acatcaattt 2000

 taccctgagg tcactgctag agacgctgat ccataaagac aatcactgcc 2050

 aacccctctt tcgtctactg caagagccaa gttccaaaat aaagcataaa 2100

 aaggtttttt aaaaggaaat gtaaaagcac atgagaatgc tagcaggctg 2150

 tggggcagct gagcagcttt tctcccccca tatctgcgtg cacttcccag 2200

 agcatcttgc atccaaacct gtaacctttc ggcaaggacg gtaacttggc 2250

 tgcatttgcc tgtcatgcgc aactggagcc agcaaccagc tatccatcag 2300

 caccccagtg gaggagttca tggaagagtt ccctctttgt ttctgcttca 2350

 tttttctttc ttttcttttc tcctaaagct tttatttaac agtgcaaaag 2400

 gatcgttttt ttttgctttt ttaaacttga atttttttaa tttacacttt 2450

 ttagttttaa ttttcttgta tattttgcta gctatgagct tttaaataaa 2500

 attgaaagtt ctggaaaagt ttgaaataat gacataaaaa gaagccttct 2550

 ttttctgaga cagcttgtct ggtaagtggc ttctctgtga attgcctgta 2600

 acacatagtg gcttctccgc ccttgtaagg tgttcagtag agctaaataa 2650

 atgtaatagc caaaccccac tctgttggta gcaattggca gccctatttc 2700

 agtttatttt ttcttctgtt ttcttctttt ctttttttaa acagtaaacc 2750

 ttaacagatg cgttcagcag actggtttgc agtgaatttt catttctttc 2800

 cttatcaccc ccttgttgta aaaagcccag cacttgaatt gttattactt 2850

 taaatgttct gtatttgtat ctgtttttat tagccaatta gtgggatttt 2900

 atgccagttg ttaaaatgag cattgatgta cccatttttt aaaaaagcaa 2950

 gcacagcctt tgcccaaaac tgtcatccta acgtttgtca ttccagtttg 3000

 agttaatgtg ctgagcattt ttttaaaaga agctttgtaa taaaacattt 3050

 ttaaaaattg tcatttaaaa aaaaaaaaaa aaaa 3084

<210> 3624
<211> 399
<212> PRT
<213> Homo sapien

<400> 3624
 Met Pro Gln Leu Ser Gly Gly Gly Gly Gly Gly Gly Gly Asp Pro
   1               5                  10                  15

 Glu Leu Cys Ala Thr Asp Glu Met Ile Pro Phe Lys Asp Glu Gly
                  20                  25                  30

 Asp Pro Gln Lys Glu Lys Ile Phe Ala Glu Ile Ser His Pro Glu
                  35                  40                  45

 Glu Glu Gly Asp Leu Ala Asp Ile Lys Ser Ser Leu Val Asn Glu
                  50                  55                  60

 Ser Glu Ile Ile Pro Ala Ser Asn Gly His Glu Val Ala Arg Gln
                  65                  70                  75

 Ala Gln Thr Ser Gln Glu Pro Tyr His Asp Lys Ala Arg Glu His
                  80                  85                  90

 Pro Asp Asp Gly Lys His Pro Asp Gly Gly Leu Tyr Asn Lys Gly
                  95                 100                 105

 Pro Ser Tyr Ser Ser Tyr Ser Gly Tyr Ile Met Met Pro Asn Met
                 110                 115                 120

 Asn Asn Asp Pro Tyr Met Ser Asn Gly Ser Leu Ser Pro Pro Ile
                 125                 130                 135

 Pro Arg Thr Ser Asn Lys Val Pro Val Val Gln Pro Ser His Ala
                 140                 145                 150

 Val His Pro Leu Thr Pro Leu Ile Thr Tyr Ser Asp Glu His Phe
                 155                 160                 165

 Ser Pro Gly Ser His Pro Ser His Ile Pro Ser Asp Val Asn Ser
                 170                 175                 180

 Lys Gln Gly Met Ser Arg His Pro Pro Ala Pro Asp Ile Pro Thr
                 185                 190                 195

 Phe Tyr Pro Leu Ser Pro Gly Gly Val Gly Gln Ile Thr Pro Pro
                 200                 205                 210

 Leu Gly Trp Gln Gly Gln Pro Val Tyr Pro Ile Thr Gly Gly Phe
                 215                 220                 225

 Arg Gln Pro Tyr Pro Ser Ser Leu Ser Val Asp Thr Ser Met Ser
                 230                 235                 240

 Arg Phe Ser His His Met Ile Pro Gly Pro Pro Gly Pro His Thr
                 245                 250                 255

 Thr Gly Ile Pro His Pro Ala Ile Val Thr Pro Gln Val Lys Gln
                 260                 265                 270

 Glu His Pro His Thr Asp Ser Asp Leu Met His Val Lys Pro Gln
                 275                 280                 285

 His Glu Gln Arg Lys Glu Gln Glu Pro Lys Arg Pro His Ile Lys
                 290                 295                 300

 Lys Pro Leu Asn Ala Phe Met Leu Tyr Met Lys Glu Met Arg Ala
                 305                 310                 315

 Asn Val Val Ala Glu Cys Thr Leu Lys Glu Ser Ala Ala Ile Asn
                 320                 325                 330

 Gln Ile Leu Gly Arg Arg Trp His Ala Leu Ser Arg Glu Glu Gln
                 335                 340                 345

 Ala Lys Tyr Tyr Glu Leu Ala Arg Lys Glu Arg Gln Leu His Met
                 350                 355                 360

 Gln Leu Tyr Pro Gly Trp Ser Ala Arg Asp Asn Tyr Gly Lys Lys
                 365                 370                 375

 Lys Lys Arg Lys Arg Glu Lys Leu Gln Glu Ser Ala Ser Gly Thr
                 380                 385                 390

 Gly Pro Arg Met Thr Ala Ala Tyr Ile
                 395

<210> 3625
<211> 1881
<212> DNA
<213> Homo sapien

<400> 3625
 ggcacgaggg ttagattagt ctgaagccgc caccagcccc aggcccccgt 50

 gcagaagaaa agcgggaggg aacggcggag gccgccgctg ccctgcaccg 100

 ccctcctgga ggccacttgg agagtccggc cccgaggagg ccatggccac 150

 aagtgcccac agctggcccc aggttgccag cgtcgctaca gcccagacca 200

 aggcagaata atctccggat gagctggtgg caccgctgag cctttggtct 250

 caccagggct tcctgttgct ggcaggcggg gtggagcgga gctgctggga 300

 ggctgctgga taggagaggg gtcacggctg cggaagagga ggttcttcgg 350

 gacacccgtg gatggacacg gcaaggaaac accaggccaa ccacagctgg 400

 ggataaaata gcacaaccac accctgccgt ccagcgcctc ccagcctgtg 450

 ccccttccta gtaccaccag caaccatcaa tcccgtctcc tcctgcctcc 500

 tctcctgcaa tccaccccgc cacgactatc gccatggcag ccctgatcgc 550

 agagaacttc cgcttcctgt cacttttctt caagagcaag gatgtgatga 600

 ttttcaacgg cctggtggca ctgggcacgg tgggcagcca ggagctgttc 650

 tctgtggtgg ccttccactg cccctgctcg ccggcccgga actacctgta 700

 cgggctggcg gccatcggcg tgcccgccct ggtgctcttc atcattggca 750

 tcatcctcaa caaccacacc tggaacctcg tggccgagtg ccagcaccgg 800

 aggaccaaga actgctccgc cgcccccacc ttcctccttc taagctccat 850

 cctgggacgt gcggctgtgg cccctgtcac ctggtctgtc atctccctgc 900

 tgcgtggtga ggcttatgtc tgtgctctca gtgagttcgt ggacccttcc 950

 tcactcacgg ccagggaaga gcacttccca tcagcccacg ccactgaaat 1000

 cctggccagg ttcccctgca aggagaaccc tgacaacctg tcagacttcc 1050

 gggaggaggt cagccgcagg ctcaggtatg agtcccagct ctttggatgg 1100

 ctgctcatcg gcgtggtggc catcctggtg ttcctgacca agtgcctcaa 1150

 gcattactgc tcaccactca gctaccgcca ggaggcctac tgggcgcagt 1200

 accgcgccaa tgaggaccag ctgttccagc gcacggccga ggtgcactct 1250

 cgggtgctcg ctgccaacaa tgtgcgccgc ttctttggct ttgtggcgct 1300

 caacaaggat gatgaggaac tgattgccaa cttcccagtg gaaggcacgc 1350

 agccacggcc acagtggaat gccatcaccg gcgtctactt gtaccgtgag 1400

 aaccagggcc tcccactcta cagccgcctg cacaagtggg cccagggtct 1450

 ggcaggcaac ggcgcggccc ctgacaacgt ggagatggcc ctgctcccct 1500

 cctaaggagg tgcttcccat gctctttgta aatggcacta cttggtccca 1550

 aactgaaccc cactgcttgc tcacatccat atcagaaggg gatttttaaa 1600

 aaactgttat cttcttggcc aggggaaagg accacaaggc aatctggggt 1650

 gtggacagac ccagtagaca atggaagccc agccagcagg gccaggtgac 1700

 agtgaagctc accagtgggc tcctttatgg tactctatgc agttaacatg 1750

 tatctagctg catagggaca cccagcgcag cagtgcacca ctgggaagtg 1800

 gcctccagtg cagcctctgg ccttatttta tatatttaaa tttttgataa 1850

 agtttttctt actaaaaaaa aaaaaaaaaa a 1881

<210> 3626
<211> 323
<212> PRT
<213> Homo sapien

<400> 3626
 Met Ala Ala Leu Ile Ala Glu Asn Phe Arg Phe Leu Ser Leu Phe
   1               5                  10                  15

 Phe Lys Ser Lys Asp Val Met Ile Phe Asn Gly Leu Val Ala Leu
                  20                  25                  30

 Gly Thr Val Gly Ser Gln Glu Leu Phe Ser Val Val Ala Phe His
                  35                  40                  45

 Cys Pro Cys Ser Pro Ala Arg Asn Tyr Leu Tyr Gly Leu Ala Ala
                  50                  55                  60

 Ile Gly Val Pro Ala Leu Val Leu Phe Ile Ile Gly Ile Ile Leu
                  65                  70                  75

 Asn Asn His Thr Trp Asn Leu Val Ala Glu Cys Gln His Arg Arg
                  80                  85                  90

 Thr Lys Asn Cys Ser Ala Ala Pro Thr Phe Leu Leu Leu Ser Ser
                  95                 100                 105

 Ile Leu Gly Arg Ala Ala Val Ala Pro Val Thr Trp Ser Val Ile
                 110                 115                 120

 Ser Leu Leu Arg Gly Glu Ala Tyr Val Cys Ala Leu Ser Glu Phe
                 125                 130                 135

 Val Asp Pro Ser Ser Leu Thr Ala Arg Glu Glu His Phe Pro Ser
                 140                 145                 150

 Ala His Ala Thr Glu Ile Leu Ala Arg Phe Pro Cys Lys Glu Asn
                 155                 160                 165

 Pro Asp Asn Leu Ser Asp Phe Arg Glu Glu Val Ser Arg Arg Leu
                 170                 175                 180

 Arg Tyr Glu Ser Gln Leu Phe Gly Trp Leu Leu Ile Gly Val Val
                 185                 190                 195

 Ala Ile Leu Val Phe Leu Thr Lys Cys Leu Lys His Tyr Cys Ser
                 200                 205                 210

 Pro Leu Ser Tyr Arg Gln Glu Ala Tyr Trp Ala Gln Tyr Arg Ala
                 215                 220                 225

 Asn Glu Asp Gln Leu Phe Gln Arg Thr Ala Glu Val His Ser Arg
                 230                 235                 240

 Val Leu Ala Ala Asn Asn Val Arg Arg Phe Phe Gly Phe Val Ala
                 245                 250                 255

 Leu Asn Lys Asp Asp Glu Glu Leu Ile Ala Asn Phe Pro Val Glu
                 260                 265                 270

 Gly Thr Gln Pro Arg Pro Gln Trp Asn Ala Ile Thr Gly Val Tyr
                 275                 280                 285

 Leu Tyr Arg Glu Asn Gln Gly Leu Pro Leu Tyr Ser Arg Leu His
                 290                 295                 300

 Lys Trp Ala Gln Gly Leu Ala Gly Asn Gly Ala Ala Pro Asp Asn
                 305                 310                 315

 Val Glu Met Ala Leu Leu Pro Ser
                 320

<210> 3627
<211> 1411
<212> DNA
<213> Homo sapien

<400> 3627
 ggcacgaggg agaggcagga ggacaccgag ttccccgtgt tggcctccag 50

 gtcctgtgct tgcggagccg tccggcggct gggatcgagc cccgacaatg 100

 ggcaacgcgc aggagcggcc gtcagagact atcgaccgcg agcggaaacg 150

 cctggtcgag acgctgcagg cggactcggg actgctgttg gacgcgctgc 200

 tggcgcgggg cgtgctcacc gggccagagt acgaggcatt ggatgcactg 250

 cctgatgccg agcgcagggt gcgccgccta ctgctgctgg tgcagggcaa 300

 gggcgaggcc gcctgccagg agctgctacg ctgtgcccag cgtaccgcgg 350

 gcgcgccgga ccccgcttgg gactggcagc acgtgggtcc gggctaccgg 400

 gaccgcagct atgaccctcc atgcccaggc cactggacgc cggaggcacc 450

 cggctcgggg accacatgcc ccgggttgcc cagagcttca gaccctgacg 500

 aggccggggg ccctgagggc tccgaggcgg tgcaatccgg gaccccggag 550

 gagccagagc cagagctgga agctgaggcc tctaaagagg ctgaaccgga 600

 gccggagcca gagccagagc tggaacccga ggctgaagca gaaccagagc 650

 cggaactgga gccagaaccg gacccagagc ccgagcccga cttcgaggaa 700

 agggacgagt ccgaagattc ctgaaggcca gagctctgac aggcggtgcc 750

 ccgcccatgc tggataggac ctgggatgct gctggagctg aatcggatgc 800

 caccaaggct cggtccagcc cagtaccgct ggaagtgaat aaactccgga 850

 gggtcggacg ggacctgggc tctctccacg attctggctg tttgcccagg 900

 aacttagggt gggtacctct gagtcccagg gacctgggca ggcccaagcc 950

 caccacgagc atcatccagt cctcagccct aatctgccct taggagtcca 1000

 ggctgcaccc tggagatccc aaacctagcc ccctagtggg acaaggacct 1050

 gaccctcctg cccgcataca caacccattt cccctggtga gccacttggc 1100

 agcatatgta ggtaccagct caaccccacg caagttcctg agctgaacat 1150

 ggagcaaggg gagggtgact tctctccaca tagggagggc ttagagctca 1200

 cagccttggg aagtgagact agaagagggg agcagaaagg gaccttgagt 1250

 agacaaaggc cacacacatc attgtcatta ctgttttaat tgtctggctt 1300

 ctctctggac tgggagctca gtgaggattc tgaccagtga cttacacaaa 1350

 aggcgctcta tacatattat aatatattcg cttactaaat gaaaaaaaaa 1400

 aaaaaaaaaa a 1411

<210> 3628
<211> 208
<212> PRT
<213> Homo sapien

<400> 3628
 Met Gly Asn Ala Gln Glu Arg Pro Ser Glu Thr Ile Asp Arg Glu
   1               5                  10                  15

 Arg Lys Arg Leu Val Glu Thr Leu Gln Ala Asp Ser Gly Leu Leu
                  20                  25                  30

 Leu Asp Ala Leu Leu Ala Arg Gly Val Leu Thr Gly Pro Glu Tyr
                  35                  40                  45

 Glu Ala Leu Asp Ala Leu Pro Asp Ala Glu Arg Arg Val Arg Arg
                  50                  55                  60

 Leu Leu Leu Leu Val Gln Gly Lys Gly Glu Ala Ala Cys Gln Glu
                  65                  70                  75

 Leu Leu Arg Cys Ala Gln Arg Thr Ala Gly Ala Pro Asp Pro Ala
                  80                  85                  90

 Trp Asp Trp Gln His Val Gly Pro Gly Tyr Arg Asp Arg Ser Tyr
                  95                 100                 105

 Asp Pro Pro Cys Pro Gly His Trp Thr Pro Glu Ala Pro Gly Ser
                 110                 115                 120

 Gly Thr Thr Cys Pro Gly Leu Pro Arg Ala Ser Asp Pro Asp Glu
                 125                 130                 135

 Ala Gly Gly Pro Glu Gly Ser Glu Ala Val Gln Ser Gly Thr Pro
                 140                 145                 150

 Glu Glu Pro Glu Pro Glu Leu Glu Ala Glu Ala Ser Lys Glu Ala
                 155                 160                 165

 Glu Pro Glu Pro Glu Pro Glu Pro Glu Leu Glu Pro Glu Ala Glu
                 170                 175                 180

 Ala Glu Pro Glu Pro Glu Leu Glu Pro Glu Pro Asp Pro Glu Pro
                 185                 190                 195

 Glu Pro Asp Phe Glu Glu Arg Asp Glu Ser Glu Asp Ser
                 200                 205

<210> 3629
<211> 1977
<212> DNA
<213> Homo sapien

<400> 3629
 ggcacgagga tttcctcatc gtcaagcttt gttcctcgtg ggggctagaa 50

 atctctttcc agttccagat tgtgaagggt tcctgagtaa gcagcgtgtc 100

 tccatccccc tctctagggg ctcttggatg gaccttgcac tctagaaggg 150

 acaatggact tctggctttg gccactttac ttcctgccag tatcgggggc 200

 cctgaggatc ctcccagaag taaaggtaga gggggagctg ggcggatcag 250

 ttaccatcaa gtgcccactt cctgaaatgc atgtgaggat atatctgtgc 300

 cgggagatgg ctggatctgg aacatgtggt accgtggtat ccaccaccaa 350

 cttcatcaag gcagaataca agggccgagt tactctgaag caatacccac 400

 gcaagaatct gttcctagtg gaggtaacac agctgacaga aagtgacagc 450

 ggagtctatg cctgcggagc gggcatgaac acagaccggg gaaagaccca 500

 gaaagtcacc ctgaatgtcc acagtgaata cgagccatca tgggaagagc 550

 agccaatgcc tgagactcca aaatggtttc atctgcccta tttgttccag 600

 atgcctgcat atgccagttc ttccaaattc gtaaccagag ttaccacacc 650

 agctcaaagg ggcaaggtcc ctccagttca ccactcctcc cccaccaccc 700

 aaatcaccca ccgccctcga gtgtccagag catcttcagt agcaggtgac 750

 aagccccgaa ccttcctgcc atccactaca gcctcaaaaa tctcagctct 800

 ggaggggctg ctcaagcccc agacgcccag ctacaaccac cacaccaggc 850

 tgcacaggca gagagcactg gactatggct cacagtctgg gagggaaggc 900

 caaggatttc acatcctgat cccgaccatc ctgggccttt tcctgctggc 950

 acttctgggg ctggtggtga aaagggccgt tgaaaggagg aaagccctct 1000

 ccaggcgggc ccgccgactg gccgtgagga tgcgcgccct ggagagctcc 1050

 cagaggcccc gcgggtcgcc gcgaccgcgc tcccaaaaca acatctacag 1100

 cgcctgcccg cggcgcgctc gtggagcgga cgctgcaggc acaggggagg 1150

 cccccgttcc cggccccgga gcgccgttgc cccccgcccc gctgcaggtg 1200

 tctgaatctc cctggctcca tgccccatct ctgaagacca gctgtgaata 1250

 cgtgagcctc taccaccagc ctgccgccat gatggaggac agtgattcag 1300

 atgactacat caatgttcct gcctgacaac tccccagcta tcccccaacc 1350

 ccaggctcgg actgtggtgc caaggagtct catctatctg ctgatgtcca 1400

 atacctgctt catgtgttct cagagccctc atcacttccc atgccccatc 1450

 tcgactccca tccccatcta tctgtgccct gagcatggct ctgcccccag 1500

 gtcgtcttgc acaccttggc agccccctgt agttgacagg taagctgtag 1550

 gcatgtagag caattgtccc aatgccactt gcttcctttc caagccgtcg 1600

 aacagactgt gggatttgca gagtgtttct tccatgtctt tgaccacagg 1650

 gttgttgctg cccaggctct agatcacatg gcatcaggct ggggcagagg 1700

 catagctatt gtctcgggca tccttcccag ggttgggtct tacacaaata 1750

 gaaggctctt gctctgagtt atgtgacatg cctcagcccc atggactaag 1800

 caggggtctg gtataaaaac actcctggaa acgcctttgc cctgatccaa 1850

 atgttagcac ttgctagtga acgtctactt atctcaagtt ctatgctaaa 1900

 ggcaatttat cttgatgtga tgataaacca aacttattag caagatatgc 1950

 atatatatca aaaaaaaaaa aaaaaaa 1977

<210> 3630
<211> 390
<212> PRT
<213> Homo sapien

<400> 3630
 Met Asp Phe Trp Leu Trp Pro Leu Tyr Phe Leu Pro Val Ser Gly
   1               5                  10                  15

 Ala Leu Arg Ile Leu Pro Glu Val Lys Val Glu Gly Glu Leu Gly
                  20                  25                  30

 Gly Ser Val Thr Ile Lys Cys Pro Leu Pro Glu Met His Val Arg
                  35                  40                  45

 Ile Tyr Leu Cys Arg Glu Met Ala Gly Ser Gly Thr Cys Gly Thr
                  50                  55                  60

 Val Val Ser Thr Thr Asn Phe Ile Lys Ala Glu Tyr Lys Gly Arg
                  65                  70                  75

 Val Thr Leu Lys Gln Tyr Pro Arg Lys Asn Leu Phe Leu Val Glu
                  80                  85                  90

 Val Thr Gln Leu Thr Glu Ser Asp Ser Gly Val Tyr Ala Cys Gly
                  95                 100                 105

 Ala Gly Met Asn Thr Asp Arg Gly Lys Thr Gln Lys Val Thr Leu
                 110                 115                 120

 Asn Val His Ser Glu Tyr Glu Pro Ser Trp Glu Glu Gln Pro Met
                 125                 130                 135

 Pro Glu Thr Pro Lys Trp Phe His Leu Pro Tyr Leu Phe Gln Met
                 140                 145                 150

 Pro Ala Tyr Ala Ser Ser Ser Lys Phe Val Thr Arg Val Thr Thr
                 155                 160                 165

 Pro Ala Gln Arg Gly Lys Val Pro Pro Val His His Ser Ser Pro
                 170                 175                 180

 Thr Thr Gln Ile Thr His Arg Pro Arg Val Ser Arg Ala Ser Ser
                 185                 190                 195

 Val Ala Gly Asp Lys Pro Arg Thr Phe Leu Pro Ser Thr Thr Ala
                 200                 205                 210

 Ser Lys Ile Ser Ala Leu Glu Gly Leu Leu Lys Pro Gln Thr Pro
                 215                 220                 225

 Ser Tyr Asn His His Thr Arg Leu His Arg Gln Arg Ala Leu Asp
                 230                 235                 240

 Tyr Gly Ser Gln Ser Gly Arg Glu Gly Gln Gly Phe His Ile Leu
                 245                 250                 255

 Ile Pro Thr Ile Leu Gly Leu Phe Leu Leu Ala Leu Leu Gly Leu
                 260                 265                 270

 Val Val Lys Arg Ala Val Glu Arg Arg Lys Ala Leu Ser Arg Arg
                 275                 280                 285

 Ala Arg Arg Leu Ala Val Arg Met Arg Ala Leu Glu Ser Ser Gln
                 290                 295                 300

 Arg Pro Arg Gly Ser Pro Arg Pro Arg Ser Gln Asn Asn Ile Tyr
                 305                 310                 315

 Ser Ala Cys Pro Arg Arg Ala Arg Gly Ala Asp Ala Ala Gly Thr
                 320                 325                 330

 Gly Glu Ala Pro Val Pro Gly Pro Gly Ala Pro Leu Pro Pro Ala
                 335                 340                 345

 Pro Leu Gln Val Ser Glu Ser Pro Trp Leu His Ala Pro Ser Leu
                 350                 355                 360

 Lys Thr Ser Cys Glu Tyr Val Ser Leu Tyr His Gln Pro Ala Ala
                 365                 370                 375

 Met Met Glu Asp Ser Asp Ser Asp Asp Tyr Ile Asn Val Pro Ala
                 380                 385                 390

<210> 3631
<211> 1977
<212> DNA
<213> Homo sapien

<400> 3631
 ggcacgagga tttcctcatc gtcaagcttt gttcctcgtg ggggctagaa 50

 atctctttcc agttccagat tgtgaagggt tcctgagtaa gcagcgtgtc 100

 tccatccccc tctctagggg ctcttggatg gaccttgcac tctagaaggg 150

 acaatggact tctggctttg gccactttac ttcctgccag tatcgggggc 200

 cctgaggatc ctcccagaag taaaggtaga gggggagctg ggcggatcag 250

 ttaccatcaa gtgcccactt cctgaaatgc atgtgaggat atatctgtgc 300

 cgggagatgg ctggatctgg aacatgtggt accgtggtat ccaccaccaa 350

 cttcatcaag gcagaataca agggccgagt tactctgaag caatacccac 400

 gcaagaatct gttcctagtg gaggtaacac agctgacaga aagtgacagc 450

 ggagtctatg cctgcggagc gggcatgaac acagaccggg gaaagaccca 500

 gaaagtcacc ctgaatgtcc acagtgaata cgagccatca tgggaagagc 550

 agccaatgcc tgagactcca aaatggtttc atctgcccta tttgttccag 600

 atgcctgcat atgccagttc ttccaaattc gtaaccagag ttaccacacc 650

 agctcaaagg ggcaaggtcc ctccagttca ccactcctcc cccaccaccc 700

 aaatcaccca ccgccctcga gtgtccagag catcttcagt agcaggtgac 750

 aagccccgaa ccttcctgcc atccactaca gcctcaaaaa tctcagctct 800

 ggaggggctg ctcaagcccc agacgcccag ctacaaccac cacaccaggc 850

 tgcacaggca gagagcactg gactatggct cacagtctgg gagggaaggc 900

 caaggatttc acatcctgat cccgaccatc ctgggccttt tcctgctggc 950

 acttctgggg ctggtggtga aaagggccgt tgaaaggagg aaagccctct 1000

 ccaggcgggc ccgccgactg gccgtgagga tgcgcgccct ggagagctcc 1050

 cagaggcccc gcgggtcgcc gcgaccgcgc tcccaaaaca acatctacag 1100

 cgcctgcccg cggcgcgctc gtggagcgga cgctgcaggc acaggggagg 1150

 cccccgttcc cggccccgga gcgccgttgc cccccgcccc gctgcaggtg 1200

 tctgaatctc cctggctcca tgccccatct ctgaagacca gctgtgaata 1250

 cgtgagcctc taccaccagc ctgccgccat gatggaggac agtgattcag 1300

 atgactacat caatgttcct gcctgacaac tccccagcta tcccccaacc 1350

 ccaggctcgg actgtggtgc caaggagtct catctatctg ctgatgtcca 1400

 atacctgctt catgtgttct cagagccctc atcacttccc atgccccatc 1450

 tcgactccca tccccatcta tctgtgccct gagcatggct ctgcccccag 1500

 gtcgtcttgc acaccttggc agccccctgt agttgacagg taagctgtag 1550

 gcatgtagag caattgtccc aatgccactt gcttcctttc caagccgtcg 1600

 aacagactgt gggatttgca gagtgtttct tccatgtctt tgaccacagg 1650

 gttgttgctg cccaggctct agatcacatg gcatcaggct ggggcagagg 1700

 catagctatt gtctcgggca tccttcccag ggttgggtct tacacaaata 1750

 gaaggctctt gctctgagtt atgtgacatg cctcagcccc atggactaag 1800

 caggggtctg gtataaaaac actcctggaa acgcctttgc cctgatccaa 1850

 atgttagcac ttgctagtga acgtctactt atctcaagtt ctatgctaaa 1900

 ggcaatttat cttgatgtga tgataaacca aacttattag caagatatgc 1950

 atatatatca aaaaaaaaaa aaaaaaa 1977

<210> 3632
<211> 390
<212> PRT
<213> Homo sapien

<400> 3632
 Met Asp Phe Trp Leu Trp Pro Leu Tyr Phe Leu Pro Val Ser Gly
   1               5                  10                  15

 Ala Leu Arg Ile Leu Pro Glu Val Lys Val Glu Gly Glu Leu Gly
                  20                  25                  30

 Gly Ser Val Thr Ile Lys Cys Pro Leu Pro Glu Met His Val Arg
                  35                  40                  45

 Ile Tyr Leu Cys Arg Glu Met Ala Gly Ser Gly Thr Cys Gly Thr
                  50                  55                  60

 Val Val Ser Thr Thr Asn Phe Ile Lys Ala Glu Tyr Lys Gly Arg
                  65                  70                  75

 Val Thr Leu Lys Gln Tyr Pro Arg Lys Asn Leu Phe Leu Val Glu
                  80                  85                  90

 Val Thr Gln Leu Thr Glu Ser Asp Ser Gly Val Tyr Ala Cys Gly
                  95                 100                 105

 Ala Gly Met Asn Thr Asp Arg Gly Lys Thr Gln Lys Val Thr Leu
                 110                 115                 120

 Asn Val His Ser Glu Tyr Glu Pro Ser Trp Glu Glu Gln Pro Met
                 125                 130                 135

 Pro Glu Thr Pro Lys Trp Phe His Leu Pro Tyr Leu Phe Gln Met
                 140                 145                 150

 Pro Ala Tyr Ala Ser Ser Ser Lys Phe Val Thr Arg Val Thr Thr
                 155                 160                 165

 Pro Ala Gln Arg Gly Lys Val Pro Pro Val His His Ser Ser Pro
                 170                 175                 180

 Thr Thr Gln Ile Thr His Arg Pro Arg Val Ser Arg Ala Ser Ser
                 185                 190                 195

 Val Ala Gly Asp Lys Pro Arg Thr Phe Leu Pro Ser Thr Thr Ala
                 200                 205                 210

 Ser Lys Ile Ser Ala Leu Glu Gly Leu Leu Lys Pro Gln Thr Pro
                 215                 220                 225

 Ser Tyr Asn His His Thr Arg Leu His Arg Gln Arg Ala Leu Asp
                 230                 235                 240

 Tyr Gly Ser Gln Ser Gly Arg Glu Gly Gln Gly Phe His Ile Leu
                 245                 250                 255

 Ile Pro Thr Ile Leu Gly Leu Phe Leu Leu Ala Leu Leu Gly Leu
                 260                 265                 270

 Val Val Lys Arg Ala Val Glu Arg Arg Lys Ala Leu Ser Arg Arg
                 275                 280                 285

 Ala Arg Arg Leu Ala Val Arg Met Arg Ala Leu Glu Ser Ser Gln
                 290                 295                 300

 Arg Pro Arg Gly Ser Pro Arg Pro Arg Ser Gln Asn Asn Ile Tyr
                 305                 310                 315

 Ser Ala Cys Pro Arg Arg Ala Arg Gly Ala Asp Ala Ala Gly Thr
                 320                 325                 330

 Gly Glu Ala Pro Val Pro Gly Pro Gly Ala Pro Leu Pro Pro Ala
                 335                 340                 345

 Pro Leu Gln Val Ser Glu Ser Pro Trp Leu His Ala Pro Ser Leu
                 350                 355                 360

 Lys Thr Ser Cys Glu Tyr Val Ser Leu Tyr His Gln Pro Ala Ala
                 365                 370                 375

 Met Met Glu Asp Ser Asp Ser Asp Asp Tyr Ile Asn Val Pro Ala
                 380                 385                 390

<210> 3633
<211> 2734
<212> DNA
<213> Homo sapien

<400> 3633
 cccgctcccc gcaggggtgg agcctgagcg aggagcccgc gagctctcct 50

 ctctcctctg gtctccgcgg atgacgagtg gctggataac atggagtcgg 100

 gcaagatggc gcctcccaag aacgctccga gagatgcctt ggtgatggca 150

 cagatcctga aggatatggg aatcacagag tatgaaccaa gggttataaa 200

 tcaaatgttg gaatttgctt tccgttatgt gactacaatt ctggatgatg 250

 caaaaattta ttcgagccat gctaagaaac ctaatgttga tgcagatgat 300

 gtgagactgg caatccagtg tcgtgctgac caatctttta cctctcctcc 350

 cccaagagat tttttactgg atatcgcaag gcagaaaaat caaacccctt 400

 tgccactgat taagccatat gcaggaccta gactgccacc tgatagatac 450

 tgcttaacag ctccaaacta taggctgaag tccttaatta aaaagggacc 500

 taaccaaggg agactagttc cacgattaag tgttggtgct gttagtagca 550

 aacctactac tcctactata gcaaccccac aaacggtgtc tgtcccaaat 600

 aaagttgcaa ctccaatgtc agtgacaagc caaagattta cggtgcagat 650

 tccaccttct cagtccacac ctgtcaaacc agttcctgca acaactgcag 700

 ttcaaaatgt tctgattaat ccttcaatga ttgggcccaa aaatattctt 750

 attaccacca acatggtttc gtcacagaac acagccaatg aagcaaaccc 800

 actgaagaga aaacatgaag atgatgatga caatgatatt atgtaaggaa 850

 tatagtctag tctagatgca tttcaaaagg aaagttggtt ttgagcccag 900

 tatactgaac tagaatattc tagatcttgt tttaccttaa aagactgaaa 950

 tgtagctgca gtatttttcg tcagttaaaa ctgttagatc tctttagtaa 1000

 acatacaaat gtgtttttca gtaggcttca attacaaaca gttaagtact 1050

 tgtttcttaa tagtttcatt aatgttgagt cctaatatgg caattctgtt 1100

 tttgagacac ttttctgcct tctatcactg atagtagcat ttaagtttca 1150

 gattctacag cctagtcagc agatttatct ttgacagcat aatttctgat 1200

 ctacatttaa atactacttt attttataag gtaatatagt tacttactgt 1250

 cactagctaa tttttttttt ttaccaaatc tctcaatata ggaaacattt 1300

 tttggaaagg atggatttag aggagagatt ctaaatccat tttggatgta 1350

 tttgtttctt tgacttcctt aacttccaaa ctcaactccc tttctagatc 1400

 ccattcattt tctgcacctc ccccataggc ttgtttctct ccattgctat 1450

 taaatgtaga aggccatacc tggaatttta aaaatattat tcctggtaat 1500

 acagctcagt gtcattttcc tatttttaaa acatgctcta catgcctaat 1550

 gtttcgtgat tcactttaac ctgatggttt gcatttgctg tttttcactc 1600

 ttatgtcaga gcagttgggt tttacccctt agtttttatg cctgttaagc 1650

 tttactgtgc ttttgacagg tagttttggg tcagttatat tcagttttag 1700

 tattgtattc caagttgata actcttccat gtttcacatt tctaaattta 1750

 acagagatgc tgtagcttaa aacatgtttt gataagtaat tacactggac 1800

 ctaggcaaaa ccactgaaga acaagtgttc ctttttacca catacatatt 1850

 atgttttgat cactgctgct tgagccccgc tattggtata attcagatca 1900

 tattagcttg ttgctgagga tgtcacatat aagacaggat caaacctgaa 1950

 agacactaat ggttcatcct ctataaggcc aacaaagaaa acaaattaat 2000

 gtgatgtaac ttgcatttat gtgcactctg cataggtttc ccaataatac 2050

 tgtaatgttg ctgaacacct ttccctgttt tccatttata cacatattaa 2100

 agtcatattg ggaaagatgg caaagctttt gagaatataa acacacctgt 2150

 tttgtttttc ttaagttcaa catacttttg tagaatttgt aaaataaatg 2200

 ttcgtatcat aattgagaat ttatagccaa ggatcctcaa aacagaagtt 2250

 tcatcttagg atagtgtttg atatatctaa gaaagtccag taacagagaa 2300

 gaaatgtctc aaatgtctcg tatcagtttt agtgtttttc agtattaggg 2350

 aaaggtaata taaaaacagg taaaatgtat aaaaatagac ctgatcaaca 2400

 tcataggaga taaatattca ttatatagca taggatatta ttacttgaat 2450

 gttctcaggg aggcagcaag tcagaaggcc taggttctag tcctagctcc 2500

 atcatttacc aactgtgtga ccttacttca cctcttagcc ttgttctcct 2550

 cactagcagt aggaaagtaa cacctaccct gcctacctca cagggctgtt 2600

 gtgagggttc aattggtata tgtgaaaatt ctttcagaat tgtaaaatgc 2650

 tatatgactg taaggaatta ttgcatttgt tccaaggtta ataaaaattt 2700

 gagcttaaaa aaaaaaaaaa aaaaaaaaaa aaaa 2734

<210> 3634
<211> 251
<212> PRT
<213> Homo sapien

<400> 3634
 Met Glu Ser Gly Lys Met Ala Pro Pro Lys Asn Ala Pro Arg Asp
   1               5                  10                  15

 Ala Leu Val Met Ala Gln Ile Leu Lys Asp Met Gly Ile Thr Glu
                  20                  25                  30

 Tyr Glu Pro Arg Val Ile Asn Gln Met Leu Glu Phe Ala Phe Arg
                  35                  40                  45

 Tyr Val Thr Thr Ile Leu Asp Asp Ala Lys Ile Tyr Ser Ser His
                  50                  55                  60

 Ala Lys Lys Pro Asn Val Asp Ala Asp Asp Val Arg Leu Ala Ile
                  65                  70                  75

 Gln Cys Arg Ala Asp Gln Ser Phe Thr Ser Pro Pro Pro Arg Asp
                  80                  85                  90

 Phe Leu Leu Asp Ile Ala Arg Gln Lys Asn Gln Thr Pro Leu Pro
                  95                 100                 105

 Leu Ile Lys Pro Tyr Ala Gly Pro Arg Leu Pro Pro Asp Arg Tyr
                 110                 115                 120

 Cys Leu Thr Ala Pro Asn Tyr Arg Leu Lys Ser Leu Ile Lys Lys
                 125                 130                 135

 Gly Pro Asn Gln Gly Arg Leu Val Pro Arg Leu Ser Val Gly Ala
                 140                 145                 150

 Val Ser Ser Lys Pro Thr Thr Pro Thr Ile Ala Thr Pro Gln Thr
                 155                 160                 165

 Val Ser Val Pro Asn Lys Val Ala Thr Pro Met Ser Val Thr Ser
                 170                 175                 180

 Gln Arg Phe Thr Val Gln Ile Pro Pro Ser Gln Ser Thr Pro Val
                 185                 190                 195

 Lys Pro Val Pro Ala Thr Thr Ala Val Gln Asn Val Leu Ile Asn
                 200                 205                 210

 Pro Ser Met Ile Gly Pro Lys Asn Ile Leu Ile Thr Thr Asn Met
                 215                 220                 225

 Val Ser Ser Gln Asn Thr Ala Asn Glu Ala Asn Pro Leu Lys Arg
                 230                 235                 240

 Lys His Glu Asp Asp Asp Asp Asn Asp Ile Met
                 245                 250

<210> 3635
<211> 1954
<212> DNA
<213> Homo sapien

<400> 3635
 acaccctctg ccgactccaa gacgctgcct cttcctgcgg gcgaggcgcg 50

 cggtctggta ctcgtgcgtc ttttatcgcc tgagtttccc tccgccgact 100

 agcgcgcggg gcccggttct ccatcgcgcg cacggcagcc tagcgcaatg 150

 aggcgggcac cctgcgttcg agataagttg cgggagatag taggagcatc 200

 cacaaactgg agagaccatg tgaaggcaat ggaagaaagg aaattacttc 250

 atagtttctt ggctaaatca caggatggac tgcctcctag gagaatgaag 300

 gacagttata ttgaagttct cttgcctttg ggcagtgagc ctgaattacg 350

 agagaaatat ttgactgttc aaaacaccgt aagatttggc aggattcttg 400

 aggatcttga cagcttggga gttcttattt gttacatgca caacaaaatc 450

 cactccgcca agatgtctcc tttatcgata gttacagccc tggtggataa 500

 gattgatatg tgtaagaaga gcttgagccc agaacaggac attaagttca 550

 gtggccatgt tagctgggtc gggaagacat ccatggaagt gaagatgcaa 600

 atgttccagt tacatggtga tgaattttgt cctgttttgg atgcaacatt 650

 tgtaatggtg gctcgtgatt ctgaaaataa agggccggca tttgtaaatc 700

 cactcatccc tgaaagccca gaggaagagg agctctttag acaaggggaa 750

 ttgaacaagg ggagaagaat tgccttcagc tccacgtcgt tactgaaaat 800

 ggcccccagc gctgaggaga ggaccaccat acatgagatg tttctcagca 850

 cactggatcc aaagactata agttttcgga gtcgagtttt accctctaat 900

 gcagtgtgga tggagaattc aaaactgaag agtttggaaa tttgccaccc 950

 tcaggagcgg aacattttca atcggatctt tggtggtttc cttatgagga 1000

 aggcatatga acttgcgtgg gctactgctt gtagctttgg tggttctcga 1050

 ccgtttgtgg tagcagtaga tgacatcatg tttcagaaac ctgttgaggt 1100

 tggctcattg ctctttcttt cttcacaggt atgctttact cagaataatt 1150

 atattcaagt cagagtacac agtgaagtgg cctccctgca ggagaagcag 1200

 catacaacca ccaatgtctt tcatttcacg ttcatgtcgg aaaaagaagt 1250

 gccattggtt ttcccaaaaa catatggaga gtccatgttg tacttagatg 1300

 ggcagcggca tttcaactcc atgagtggcc cagcgacctt gagaaaggac 1350

 taccttgtgg agccctaaga acaccacatt tgttgaaaac tagcactcta 1400

 cccacagtga cgtggtatct gatgaagacc tgatcgagtg tattgatttt 1450

 agtattgctt cgtgtcctcc acacaggagg aggatgtatt cagcctttag 1500

 gatgatcaga aaagcagaaa gagagagtgg ccggatgggg ctgaggggag 1550

 aaagaattat taaacaataa atactttcaa gacaatttta attgtgaacc 1600

 taccatgttg cctcccatct tctgaaaaaa caaaaaaatt ataggcatga 1650

 gccactgcac ccggccggtg gaaagcattt ttaacaaaaa atttttaggc 1700

 caggcacagt ggtggctcat gcctgtaatc ccagcacttt gggagactga 1750

 gatgggagga tcgcttgaga ccagcctggg gaacatagtg agaccctttc 1800

 tctacaaaaa gttaaaaaat tatctgagca tggtggtgtg cacctgtagt 1850

 cccagttagg aggctgaggt gagtggattg cttgagtccg ggagtttgag 1900

 tctgcagtga gctatgatca tgccactgca ctccagtctg ggtgacagca 1950

 agac 1954

<210> 3636
<211> 406
<212> PRT
<213> Homo sapien

<400> 3636
 Met Arg Arg Ala Pro Cys Val Arg Asp Lys Leu Arg Glu Ile Val
   1               5                  10                  15

 Gly Ala Ser Thr Asn Trp Arg Asp His Val Lys Ala Met Glu Glu
                  20                  25                  30

 Arg Lys Leu Leu His Ser Phe Leu Ala Lys Ser Gln Asp Gly Leu
                  35                  40                  45

 Pro Pro Arg Arg Met Lys Asp Ser Tyr Ile Glu Val Leu Leu Pro
                  50                  55                  60

 Leu Gly Ser Glu Pro Glu Leu Arg Glu Lys Tyr Leu Thr Val Gln
                  65                  70                  75

 Asn Thr Val Arg Phe Gly Arg Ile Leu Glu Asp Leu Asp Ser Leu
                  80                  85                  90

 Gly Val Leu Ile Cys Tyr Met His Asn Lys Ile His Ser Ala Lys
                  95                 100                 105

 Met Ser Pro Leu Ser Ile Val Thr Ala Leu Val Asp Lys Ile Asp
                 110                 115                 120

 Met Cys Lys Lys Ser Leu Ser Pro Glu Gln Asp Ile Lys Phe Ser
                 125                 130                 135

 Gly His Val Ser Trp Val Gly Lys Thr Ser Met Glu Val Lys Met
                 140                 145                 150

 Gln Met Phe Gln Leu His Gly Asp Glu Phe Cys Pro Val Leu Asp
                 155                 160                 165

 Ala Thr Phe Val Met Val Ala Arg Asp Ser Glu Asn Lys Gly Pro
                 170                 175                 180

 Ala Phe Val Asn Pro Leu Ile Pro Glu Ser Pro Glu Glu Glu Glu
                 185                 190                 195

 Leu Phe Arg Gln Gly Glu Leu Asn Lys Gly Arg Arg Ile Ala Phe
                 200                 205                 210

 Ser Ser Thr Ser Leu Leu Lys Met Ala Pro Ser Ala Glu Glu Arg
                 215                 220                 225

 Thr Thr Ile His Glu Met Phe Leu Ser Thr Leu Asp Pro Lys Thr
                 230                 235                 240

 Ile Ser Phe Arg Ser Arg Val Leu Pro Ser Asn Ala Val Trp Met
                 245                 250                 255

 Glu Asn Ser Lys Leu Lys Ser Leu Glu Ile Cys His Pro Gln Glu
                 260                 265                 270

 Arg Asn Ile Phe Asn Arg Ile Phe Gly Gly Phe Leu Met Arg Lys
                 275                 280                 285

 Ala Tyr Glu Leu Ala Trp Ala Thr Ala Cys Ser Phe Gly Gly Ser
                 290                 295                 300

 Arg Pro Phe Val Val Ala Val Asp Asp Ile Met Phe Gln Lys Pro
                 305                 310                 315

 Val Glu Val Gly Ser Leu Leu Phe Leu Ser Ser Gln Val Cys Phe
                 320                 325                 330

 Thr Gln Asn Asn Tyr Ile Gln Val Arg Val His Ser Glu Val Ala
                 335                 340                 345

 Ser Leu Gln Glu Lys Gln His Thr Thr Thr Asn Val Phe His Phe
                 350                 355                 360

 Thr Phe Met Ser Glu Lys Glu Val Pro Leu Val Phe Pro Lys Thr
                 365                 370                 375

 Tyr Gly Glu Ser Met Leu Tyr Leu Asp Gly Gln Arg His Phe Asn
                 380                 385                 390

 Ser Met Ser Gly Pro Ala Thr Leu Arg Lys Asp Tyr Leu Val Glu
                 395                 400                 405

 Pro


<210> 3637
<211> 2887
<212> DNA
<213> Homo sapien

<400> 3637
 gaagcagcag gtaccccctc cacatcccta gggctctgtg atgtaggcag 50

 aggcccgtgg gagtcagcat gccgcgtggc tgggccgccc ccttgctcct 100

 gctgctgctc cagggaggct ggggctgccc cgacctcgtc tgctacaccg 150

 attacctcca gacggtcatc tgcatcctgg aaatgtggaa cctccacccc 200

 agcacgctca cccttacctg gcaagaccag tatgaagagc tgaaggacga 250

 ggccacctcc tgcagcctcc acaggtcggc ccacaatgcc acgcatgcca 300

 cctacacctg ccacatggat gtattccact tcatggccga cgacattttc 350

 agtgtcaaca tcacagacca gtctggcaac tactcccagg agtgtggcag 400

 ctttctcctg gctgagagca tcaagccggc tccccctttc aacgtgactg 450

 tgaccttctc aggacagtat aatatctcct ggcgctcaga ttacgaagac 500

 cctgccttct acatgctgaa gggcaagctt cagtatgagc tgcagtacag 550

 gaaccgggga gacccctggg ctgtgagtcc gaggagaaag ctgatctcag 600

 tggactcaag aagtgtctcc ctcctccccc tggagttccg caaagactcg 650

 agctatgagc tgcaggtgcg ggcagggccc atgcctggct cctcctacca 700

 ggggacctgg agtgaatgga gtgacccggt catctttcag acccagtcag 750

 aggagttaaa ggaaggctgg aaccctcacc tgctgcttct cctcctgctt 800

 gtcatagtct tcattcctgc cttctggagc ctgaagaccc atccattgtg 850

 gaggctatgg aagaagatat gggccgtccc cagccctgag cggttcttca 900

 tgcccctgta caagggctgc agcggagact tcaagaaatg ggtgggtgca 950

 cccttcactg gctccagcct ggagctggga ccctggagcc cagaggtgcc 1000

 ctccaccctg gaggtgtaca gctgccaccc accacggagc ccggccaaga 1050

 ggctgcagct cacggagcta caagaaccag cagagctggt ggagtctgac 1100

 ggtgtgccca agcccagctt ctggccgaca gcccagaact cggggggctc 1150

 agcttacagt gaggagaggg atcggccata cggcctggtg tccattgaca 1200

 cagtgactgt gctagatgca gaggggccat gcacctggcc ctgcagctgt 1250

 gaggatgacg gctacccagc cctggacctg gatgctggcc tggagcccag 1300

 cccaggccta gaggacccac tcttggatgc agggaccaca gtcctgtcct 1350

 gtggctgtgt ctcagctggc agccctgggc taggagggcc cctgggaagc 1400

 ctcctggaca gactaaagcc accccttgca gatggggagg actgggctgg 1450

 gggactgccc tggggtggcc ggtcacctgg aggggtctca gagagtgagg 1500

 cgggctcacc cctggccggc ctggatatgg acacgtttga cagtggcttt 1550

 gtgggctctg actgcagcag ccctgtggag tgtgacttca ccagccccgg 1600

 ggacgaagga cccccccgga gctacctccg ccagtgggtg gtcattcctc 1650

 cgccactttc gagccctgga ccccaggcca gctaatgagg ctgactggat 1700

 gtccagagct ggccaggcca ctgggccctg agccagagac aaggtcacct 1750

 gggctgtgat gtgaagacac ctgcagcctt tggtctcctg gatgggcctt 1800

 tgagcctgat gtttacagtg tctgtgtgtg tgtgtgcata tgtgtgtgtg 1850

 tgcatatgca tgtgtgtgtg tgtgtgtgtc ttaggtgcgc agtggcatgt 1900

 ccacgtgtgt gtgtgattgc acgtgcctgt gggcctggga taatgcccat 1950

 ggtactccat gcattcacct gccctgtgca tgtctggact cacggagctc 2000

 acccatgtgc acaagtgtgc acagtaaacg tgtttgtggt caacagatga 2050

 caacagccgt cctccctcct agggtcttgt gttgcaagtt ggtccacagc 2100

 atctccgggg ctttgtggga tcagggcatt gcctgtgact gaggcggagc 2150

 ccagccctcc agcgtctgcc tccaggagct gcaagaagtc catattgttc 2200

 cttatcacct gccaacagga agcgaaaggg gatggagtga gcccatggtg 2250

 acctcgggaa tggcaatttt ttgggcggcc cctggacgaa ggtctgaatc 2300

 ccgactctga taccttctgg ctgtgctacc tgagccaagt cgcctcccct 2350

 ctctgggcta gagtttcctt atccagacag tggggaaggc atgacacacc 2400

 tgggggaaat tggcgatgtc acccgtgtac ggtacgcagc ccagagcaga 2450

 ccctcaataa acgtcagctt ccttccttct gcggccagag ccgaggcggg 2500

 cgggggtgag aacatcaatc gtcagcgaca gcctgggcac ccgcggggcc 2550

 gtcccgcctg cagagggcca ctcggggggg tttccaggct taaaatcagt 2600

 ccgtttcgtc tcttggaaac agctccccac caaccaagat ttctttttct 2650

 aacttctgct actaagtttt taaaaattcc ctttatgcac ccaagagata 2700

 tttattaaac accaattacg tagcaggcca tggctcatgg gacccacccc 2750

 ccgtggcact catggagggg gctgcaggtt ggaactatgc agtgtgctcc 2800

 ggccacacat cctgctgggc cccctaccct gccccaattc aatcctgcca 2850

 ataaatcctg tcttatttgt tcatcctgga gaattga 2887

<210> 3638
<211> 538
<212> PRT
<213> Homo sapien

<400> 3638
 Met Pro Arg Gly Trp Ala Ala Pro Leu Leu Leu Leu Leu Leu Gln
   1               5                  10                  15

 Gly Gly Trp Gly Cys Pro Asp Leu Val Cys Tyr Thr Asp Tyr Leu
                  20                  25                  30

 Gln Thr Val Ile Cys Ile Leu Glu Met Trp Asn Leu His Pro Ser
                  35                  40                  45

 Thr Leu Thr Leu Thr Trp Gln Asp Gln Tyr Glu Glu Leu Lys Asp
                  50                  55                  60

 Glu Ala Thr Ser Cys Ser Leu His Arg Ser Ala His Asn Ala Thr
                  65                  70                  75

 His Ala Thr Tyr Thr Cys His Met Asp Val Phe His Phe Met Ala
                  80                  85                  90

 Asp Asp Ile Phe Ser Val Asn Ile Thr Asp Gln Ser Gly Asn Tyr
                  95                 100                 105

 Ser Gln Glu Cys Gly Ser Phe Leu Leu Ala Glu Ser Ile Lys Pro
                 110                 115                 120

 Ala Pro Pro Phe Asn Val Thr Val Thr Phe Ser Gly Gln Tyr Asn
                 125                 130                 135

 Ile Ser Trp Arg Ser Asp Tyr Glu Asp Pro Ala Phe Tyr Met Leu
                 140                 145                 150

 Lys Gly Lys Leu Gln Tyr Glu Leu Gln Tyr Arg Asn Arg Gly Asp
                 155                 160                 165

 Pro Trp Ala Val Ser Pro Arg Arg Lys Leu Ile Ser Val Asp Ser
                 170                 175                 180

 Arg Ser Val Ser Leu Leu Pro Leu Glu Phe Arg Lys Asp Ser Ser
                 185                 190                 195

 Tyr Glu Leu Gln Val Arg Ala Gly Pro Met Pro Gly Ser Ser Tyr
                 200                 205                 210

 Gln Gly Thr Trp Ser Glu Trp Ser Asp Pro Val Ile Phe Gln Thr
                 215                 220                 225

 Gln Ser Glu Glu Leu Lys Glu Gly Trp Asn Pro His Leu Leu Leu
                 230                 235                 240

 Leu Leu Leu Leu Val Ile Val Phe Ile Pro Ala Phe Trp Ser Leu
                 245                 250                 255

 Lys Thr His Pro Leu Trp Arg Leu Trp Lys Lys Ile Trp Ala Val
                 260                 265                 270

 Pro Ser Pro Glu Arg Phe Phe Met Pro Leu Tyr Lys Gly Cys Ser
                 275                 280                 285

 Gly Asp Phe Lys Lys Trp Val Gly Ala Pro Phe Thr Gly Ser Ser
                 290                 295                 300

 Leu Glu Leu Gly Pro Trp Ser Pro Glu Val Pro Ser Thr Leu Glu
                 305                 310                 315

 Val Tyr Ser Cys His Pro Pro Arg Ser Pro Ala Lys Arg Leu Gln
                 320                 325                 330

 Leu Thr Glu Leu Gln Glu Pro Ala Glu Leu Val Glu Ser Asp Gly
                 335                 340                 345

 Val Pro Lys Pro Ser Phe Trp Pro Thr Ala Gln Asn Ser Gly Gly
                 350                 355                 360

 Ser Ala Tyr Ser Glu Glu Arg Asp Arg Pro Tyr Gly Leu Val Ser
                 365                 370                 375

 Ile Asp Thr Val Thr Val Leu Asp Ala Glu Gly Pro Cys Thr Trp
                 380                 385                 390

 Pro Cys Ser Cys Glu Asp Asp Gly Tyr Pro Ala Leu Asp Leu Asp
                 395                 400                 405

 Ala Gly Leu Glu Pro Ser Pro Gly Leu Glu Asp Pro Leu Leu Asp
                 410                 415                 420

 Ala Gly Thr Thr Val Leu Ser Cys Gly Cys Val Ser Ala Gly Ser
                 425                 430                 435

 Pro Gly Leu Gly Gly Pro Leu Gly Ser Leu Leu Asp Arg Leu Lys
                 440                 445                 450

 Pro Pro Leu Ala Asp Gly Glu Asp Trp Ala Gly Gly Leu Pro Trp
                 455                 460                 465

 Gly Gly Arg Ser Pro Gly Gly Val Ser Glu Ser Glu Ala Gly Ser
                 470                 475                 480

 Pro Leu Ala Gly Leu Asp Met Asp Thr Phe Asp Ser Gly Phe Val
                 485                 490                 495

 Gly Ser Asp Cys Ser Ser Pro Val Glu Cys Asp Phe Thr Ser Pro
                 500                 505                 510

 Gly Asp Glu Gly Pro Pro Arg Ser Tyr Leu Arg Gln Trp Val Val
                 515                 520                 525

 Ile Pro Pro Pro Leu Ser Ser Pro Gly Pro Gln Ala Ser
                 530                 535

<210> 3639
<211> 936
<212> DNA
<213> Homo sapien

<400> 3639
 gagggcgcga tcctggcgtc ccccgacggc ctggggcccc aatccagagg 50

 cctgggtggg aggggaccaa gggtgtagta aggaagcgcc ttttgctgga 100

 gggcaacgga ccggggcggg gagtcgggag accagagtgg gaggaaggcg 150

 gggagtccag gttccgcccc ggagccgact tcctcctggt cggcggctgc 200

 agcggggtga gcggcggcag cggccgggga tcctggagcc atggggcgcg 250

 cgcgcgacgc catcctggat gcgctggaga acctgaccgc cgaggagctc 300

 aagaagttca agctgaagct gctgtcggtg ccgctgcgcg agggctacgg 350

 gcgcatcccg cggggcgcgc tgctgtccat ggacgccttg gacctcaccg 400

 acaagctggt cagcttctac ctggagacct acggcgccga gctcaccgct 450

 aacgtgctgc gcgacatggg cctgcaggag atggccgggc agctgcaggc 500

 ggccacgcac cagggctctg gagccgcgcc agctgggatc caggcccctc 550

 ctcagtcggc agccaagcca ggcctgcact ttatagacca gcaccgggct 600

 gcgcttatcg cgagggtcac aaacgttgag tggctgctgg atgctctgta 650

 cgggaaggtc ctgacggatg agcagtacca ggcagtgcgg gccgagccca 700

 ccaacccaag caagatgcgg aagctcttca gtttcacacc agcctggaac 750

 tggacctgca aggacttgct cctccaggcc ctaagggagt cccagtccta 800

 cctggtggag gacctggagc ggagctgagg ctccttccca gcaacactcc 850

 ggtcagcccc tggcaatccc accaaatcat cctgaatctg atctttttat 900

 acacaatata cgaaaagcca gcttgaaaaa aaaaaa 936

<210> 3640
<211> 195
<212> PRT
<213> Homo sapien

<400> 3640
 Met Gly Arg Ala Arg Asp Ala Ile Leu Asp Ala Leu Glu Asn Leu
   1               5                  10                  15

 Thr Ala Glu Glu Leu Lys Lys Phe Lys Leu Lys Leu Leu Ser Val
                  20                  25                  30

 Pro Leu Arg Glu Gly Tyr Gly Arg Ile Pro Arg Gly Ala Leu Leu
                  35                  40                  45

 Ser Met Asp Ala Leu Asp Leu Thr Asp Lys Leu Val Ser Phe Tyr
                  50                  55                  60

 Leu Glu Thr Tyr Gly Ala Glu Leu Thr Ala Asn Val Leu Arg Asp
                  65                  70                  75

 Met Gly Leu Gln Glu Met Ala Gly Gln Leu Gln Ala Ala Thr His
                  80                  85                  90

 Gln Gly Ser Gly Ala Ala Pro Ala Gly Ile Gln Ala Pro Pro Gln
                  95                 100                 105

 Ser Ala Ala Lys Pro Gly Leu His Phe Ile Asp Gln His Arg Ala
                 110                 115                 120

 Ala Leu Ile Ala Arg Val Thr Asn Val Glu Trp Leu Leu Asp Ala
                 125                 130                 135

 Leu Tyr Gly Lys Val Leu Thr Asp Glu Gln Tyr Gln Ala Val Arg
                 140                 145                 150

 Ala Glu Pro Thr Asn Pro Ser Lys Met Arg Lys Leu Phe Ser Phe
                 155                 160                 165

 Thr Pro Ala Trp Asn Trp Thr Cys Lys Asp Leu Leu Leu Gln Ala
                 170                 175                 180

 Leu Arg Glu Ser Gln Ser Tyr Leu Val Glu Asp Leu Glu Arg Ser
                 185                 190                 195

<210> 3641
<211> 3828
<212> DNA
<213> Homo sapien

<400> 3641
 cagtgccagg ctggaggcgg cagcggttgg aggcttcgcc cggctttgca 50

 gcggggactt cggcggcggc gcctcaggca cctcggcccg gacacgatga 100

 ggcgagtggt acgacagagc aagtttcggc atgtatttgg gcaagcggtg 150

 aaaaatgacc agtgctatga tgacatccgg gtttctcgtg tgacctggga 200

 tagttccttt tgtgctgtca atcccagatt tgttgccata atcatagagg 250

 caagtggggg aggagcgttc cttgtcctcc ctctgcacaa gactggtcga 300

 attgacaaat cttaccctac agtatgtggc cacacaggac cagtgctgga 350

 catagactgg tgcccacata acgatcaggt cattgccagc ggttcagagg 400

 actgcacggt catggtatgg cagatcccag aaaatggact caccctttcc 450

 ctgactgaac ctgtggtgat tttggaaggc cactcaaaga gagtcggcat 500

 cgtggcttgg catccaacgg cccgcaatgt gcttcttagt gcaggctgtg 550

 ataatgccat tatcatctgg aatgtgggaa caggggaagc ccttataaac 600

 ttggacgata tgcattcaga catgatttac aatgtgagct ggaaccggaa 650

 tggcagtctg atctgcacag cttccaaaga caagaaagtg agagtcattg 700

 atcccaggaa acaagagatt gttgctgaga aggagaaagc acatgaagga 750

 gcaagaccca tgagagccat cttcctggcc gatggcaatg tcttcaccac 800

 tgggttcagc cgcatgagcg agcggcagct ggctctctgg aatccgaaaa 850

 atatgcagga accaattgct cttcatgaga tggacactag caatggggtg 900

 ttgctgcctt tctatgaccc tgacaccagc atcatttact tatgtggaaa 950

 gggtgacagc agtattcgct attttgagat cacggatgaa tccccgtacg 1000

 tccactacct caacacattc agcagcaagg agcctcagag agggatgggt 1050

 tacatgccca agaggggact tgatgttaac aaatgtgaga ttgccagatt 1100

 cttcaaactt catgagagaa agtgtgaacc tattattatg actgttccca 1150

 ggaagtctga ccttttccaa gatgacctgt atcctgacac agcggggcca 1200

 gaggccgcgc tggaggcaga agagtggttc gaaggcaaga atgcagaccc 1250

 aatcctcatc tccttgaagc acgggtacat tccaggcaaa aacagggatc 1300

 tcaaggtggt caagaagaac attctggata gcaagcccac tgcaaacaag 1350

 aagtgcgacc tgatcagcat ccccaagaaa accacagaca cggccagtgt 1400

 gcaaaatgaa gccaagttgg atgagatttt aaaagagatc aaatctataa 1450

 aagacacaat ctgcaatcaa gatgagcgta tttccaagtt agaacagcag 1500

 atggcaaaga tagcagcctg aaggtcccac ccccacccct acagaaaaaa 1550

 tgggagcaag aacttgtgct tgggagctgg ttattggtgt ggtcctaggg 1600

 agggcggaaa gggaggcact gccatttgga gacattccat ttcagatttg 1650

 tcaaccagcg ataggccaca ttccagtaag aactcaattt gtctcccaaa 1700

 tttgcagaaa caaaacgtga tttaaaagct gagcttttta tcagaaagct 1750

 tttttgatgt tttaagtgtt atgtgacttg ttgaactttt taaaaagtgc 1800

 tacttttaaa atcccagata ctctgaattt tagaaaacaa actaattctg 1850

 attgtgtcgt gcccaagtac cctttttttt ttaatgaata gggaccaatg 1900

 ccacattgct ttttatattt ctttcttttt taatgttgcc aaaaccaaaa 1950

 gtagctttgt tttcctttgt attttgctac tttgcagtat ttgtgtgtgt 2000

 ggtttttttt ccttaatttg aaagggacag cactgtgtat gtttataaac 2050

 taaatgaaga taagatatta ttttgtataa acattcatct gagaacaatc 2100

 aaagcagtag ccacatggtg ctggctcctt tgcagcacaa acctggtcat 2150

 tttgatgact gtacaacagg aagacttgaa aaatcacgtg gattcatatt 2200

 accaccgctc tcatttcatg gagtcttctg atcaaaaaag ctcacgtcgt 2250

 atttcttctt ttcctttctc ttttctagaa attgggtgtt tgtaccagaa 2300

 tggaattttg cttctcggtt atcctgtgct tcagatgatt ataatctaac 2350

 ccaaactagc atgtgtttct gcagtttgtt acacacctag gatcatattg 2400

 cattcatcac tttaaacatc atgtttcagg ttttggtcaa tacttgacaa 2450

 gggtgcccag gacaggaaga cgtgtactgc tgagtgttcc ttcttgccct 2500

 tttcagcagc ttgcccagct cttgagtaca gtggtgggga ctaaaaatgt 2550

 gggcatgtgg agaggggtat ttgccctggg tgatcctgtt tccctgtgct 2600

 gtccccatgc tgtgttggag gaggaagtgg ctctccttcc accaacaaag 2650

 ctcctgctct accctcttcc tcacatgtgc tgcgacctct ctcagggctc 2700

 ccccagccat tccttctttc cttcctgcct tttagctcta accacattaa 2750

 gctaagacaa ggccagaggg tgcgattgaa tgagtattga gactgaggag 2800

 aatgatagag agtgaagcag aaacaggagc acagacctct gctgtagctt 2850

 taatgcatac aaacatgtcc ctccgcacaa ctaacctgcc ctgcctctcc 2900

 atctctcacc aaggctgcgt caaagcacag aggctccccg gactcggagg 2950

 gggccagaga ctgagctctg gtcacctgtt cattcctcgg ttagctggaa 3000

 ctttgccccg tttccagttt cttatagtgc atgcttggga aacaagattt 3050

 aaggagcctc tgttttggaa gggctgtctg tgattgaacg tgaaatgtgt 3100

 agtgccattg ggaccacgaa gggaattctt gcacatgctc gtgctggtgt 3150

 gggcatggga ctggctggaa acgtctgtat gcagggagcc agggtgaggg 3200

 cagagtgtgg tgacagccga acttggagta atgtccgtgt agaaaaagga 3250

 ccatgttctt atccagccaa tactgggagt gctgtctcca caatttcagg 3300

 gcatctgaat gtttgatgtg gttttgtgtg tgtgtatgta tgtgtttaat 3350

 attgaagtgg atcatgagat gtaaagaaaa caataatggc aatgacttat 3400

 attcaaatct gtatttgttt ctttatcaat gtaatctgct gaggaccttt 3450

 tgtctaagat tcagtagtgt tttaaggttc tgatatcgaa ttaatgaagt 3500

 aaagttgttg atggtggtga aacaccgtag ggcatgtggt tcaaagagaa 3550

 gcaggagggc aagggaaagt taccctgatc ttagtttgta gcttatgact 3600

 tatttaatga atggatgccc agccaagctc agagtaggcg cccaaagcat 3650

 tgtggattat tttcctgttt tgtctttttt tttttttttt tttaagccat 3700

 gacatcccag aagaggacag tgaattactc ctaggtcggc tcttatagag 3750

 tggccatagt gttctgtcaa aacacttgct tccattttca gagataaaaa 3800

 tcattgatta caaaaaaaaa aaaaaaaa 3828

<210> 3642
<211> 474
<212> PRT
<213> Homo sapien

<400> 3642
 Met Arg Arg Val Val Arg Gln Ser Lys Phe Arg His Val Phe Gly
   1               5                  10                  15

 Gln Ala Val Lys Asn Asp Gln Cys Tyr Asp Asp Ile Arg Val Ser
                  20                  25                  30

 Arg Val Thr Trp Asp Ser Ser Phe Cys Ala Val Asn Pro Arg Phe
                  35                  40                  45

 Val Ala Ile Ile Ile Glu Ala Ser Gly Gly Gly Ala Phe Leu Val
                  50                  55                  60

 Leu Pro Leu His Lys Thr Gly Arg Ile Asp Lys Ser Tyr Pro Thr
                  65                  70                  75

 Val Cys Gly His Thr Gly Pro Val Leu Asp Ile Asp Trp Cys Pro
                  80                  85                  90

 His Asn Asp Gln Val Ile Ala Ser Gly Ser Glu Asp Cys Thr Val
                  95                 100                 105

 Met Val Trp Gln Ile Pro Glu Asn Gly Leu Thr Leu Ser Leu Thr
                 110                 115                 120

 Glu Pro Val Val Ile Leu Glu Gly His Ser Lys Arg Val Gly Ile
                 125                 130                 135

 Val Ala Trp His Pro Thr Ala Arg Asn Val Leu Leu Ser Ala Gly
                 140                 145                 150

 Cys Asp Asn Ala Ile Ile Ile Trp Asn Val Gly Thr Gly Glu Ala
                 155                 160                 165

 Leu Ile Asn Leu Asp Asp Met His Ser Asp Met Ile Tyr Asn Val
                 170                 175                 180

 Ser Trp Asn Arg Asn Gly Ser Leu Ile Cys Thr Ala Ser Lys Asp
                 185                 190                 195

 Lys Lys Val Arg Val Ile Asp Pro Arg Lys Gln Glu Ile Val Ala
                 200                 205                 210

 Glu Lys Glu Lys Ala His Glu Gly Ala Arg Pro Met Arg Ala Ile
                 215                 220                 225

 Phe Leu Ala Asp Gly Asn Val Phe Thr Thr Gly Phe Ser Arg Met
                 230                 235                 240

 Ser Glu Arg Gln Leu Ala Leu Trp Asn Pro Lys Asn Met Gln Glu
                 245                 250                 255

 Pro Ile Ala Leu His Glu Met Asp Thr Ser Asn Gly Val Leu Leu
                 260                 265                 270

 Pro Phe Tyr Asp Pro Asp Thr Ser Ile Ile Tyr Leu Cys Gly Lys
                 275                 280                 285

 Gly Asp Ser Ser Ile Arg Tyr Phe Glu Ile Thr Asp Glu Ser Pro
                 290                 295                 300

 Tyr Val His Tyr Leu Asn Thr Phe Ser Ser Lys Glu Pro Gln Arg
                 305                 310                 315

 Gly Met Gly Tyr Met Pro Lys Arg Gly Leu Asp Val Asn Lys Cys
                 320                 325                 330

 Glu Ile Ala Arg Phe Phe Lys Leu His Glu Arg Lys Cys Glu Pro
                 335                 340                 345

 Ile Ile Met Thr Val Pro Arg Lys Ser Asp Leu Phe Gln Asp Asp
                 350                 355                 360

 Leu Tyr Pro Asp Thr Ala Gly Pro Glu Ala Ala Leu Glu Ala Glu
                 365                 370                 375

 Glu Trp Phe Glu Gly Lys Asn Ala Asp Pro Ile Leu Ile Ser Leu
                 380                 385                 390

 Lys His Gly Tyr Ile Pro Gly Lys Asn Arg Asp Leu Lys Val Val
                 395                 400                 405

 Lys Lys Asn Ile Leu Asp Ser Lys Pro Thr Ala Asn Lys Lys Cys
                 410                 415                 420

 Asp Leu Ile Ser Ile Pro Lys Lys Thr Thr Asp Thr Ala Ser Val
                 425                 430                 435

 Gln Asn Glu Ala Lys Leu Asp Glu Ile Leu Lys Glu Ile Lys Ser
                 440                 445                 450

 Ile Lys Asp Thr Ile Cys Asn Gln Asp Glu Arg Ile Ser Lys Leu
                 455                 460                 465

 Glu Gln Gln Met Ala Lys Ile Ala Ala
                 470

<210> 3643
<211> 1491
<212> DNA
<213> Homo sapien

<400> 3643
 gccgggtcgg ggcggggcgg cttttctgtc ggaggacgcg aaccggcacg 50

 ctgcgccttt aaggagtccg gctgggctgg gcgccggagc tgggagccgc 100

 gcgggtagga gcccggcggc aggtcccagc ccggggctag agaccgaggg 150

 ccggggtccg ggcccggcgg cgggacccag gcggttgagg ctggtcagaa 200

 tctcattttc aggacccagg cggttgaggc tggtcaggag tcagccagcc 250

 tgaaagagca ggatggatct tgatgtggtt aacatgtttg tgattgcggg 300

 cggcacgctg gccatcccaa tcctggcatt tgtggcttca tttcttctgt 350

 ggccttcagc actgataaga atctattatt ggtactggcg gaggacattg 400

 ggcatgcaag tccgctatgt tcaccatgaa gactatcagt tctgttattc 450

 cttccggggc aggcctgggc acaaaccctc catcctcatg ctccacggat 500

 tctctgccca caaggatatg tggctcagtg tggtcaagtt ccttccaaag 550

 aacctgcact tggtctgcgt ggacatgcca ggacatgagg gcaccacccg 600

 ctcctccctg gatgacctgt ccatagatgg gcaagttaag aggatacacc 650

 agtttgtaga atgcctgaag ctgaacaaaa aacctttcca cctggtaggc 700

 acctccatgg gtggccaggt ggctggggtg tatgctgctt actacccatc 750

 ggatgtctcc agcctgtgtc tcgtgtgtcc tgctggcctg cagtactcaa 800

 ctgacaatca atttgtacaa cggctcaaag aactgcaggg ctctgccgcc 850

 gtggagaaga ttcccttgat cccgtctacc ccagaagaga tgagtgaaat 900

 gcttcagctc tgctcctatg tccgcttcaa ggtgccccag cagatcctgc 950

 aaggccttgt cgatgtccgc atccctcata acaacttcta ccgaaagttg 1000

 tttttggaaa tcgtcagtga gaagtccaga tactctctcc atcagaacat 1050

 ggacaagatc aaggttccga cgcagatcat ctgggggaaa caagaccagg 1100

 tgctggatgt gtctggggca gacaatgttg gccaagtcaa ttgccaactg 1150

 ccaggtggag cttctggaaa actgtgggca ctcagtagtg atggaaaaaa 1200

 cccaggaaga cagccaagct cataatcgac tttttagctt ctgtgcaaaa 1250

 cacagacaaa caacaagaag ctggacttga aggcccccaa ctgcagcctg 1300

 gaatttttga acacagcatt ctgcttccca ttcccccaag ttttgacgca 1350

 gccaaccatt tttaagggat tcctgcccca aattgcggtt ggaagcgcca 1400

 attgacccct ggaggaaagc ccgtcccctt attccccggg tatccacggt 1450

 tccccagagc tttggggacc acggcgaaaa cctccaagat a 1491

<210> 3644
<211> 320
<212> PRT
<213> Homo sapien

<400> 3644
 Met Asp Leu Asp Val Val Asn Met Phe Val Ile Ala Gly Gly Thr
   1               5                  10                  15

 Leu Ala Ile Pro Ile Leu Ala Phe Val Ala Ser Phe Leu Leu Trp
                  20                  25                  30

 Pro Ser Ala Leu Ile Arg Ile Tyr Tyr Trp Tyr Trp Arg Arg Thr
                  35                  40                  45

 Leu Gly Met Gln Val Arg Tyr Val His His Glu Asp Tyr Gln Phe
                  50                  55                  60

 Cys Tyr Ser Phe Arg Gly Arg Pro Gly His Lys Pro Ser Ile Leu
                  65                  70                  75

 Met Leu His Gly Phe Ser Ala His Lys Asp Met Trp Leu Ser Val
                  80                  85                  90

 Val Lys Phe Leu Pro Lys Asn Leu His Leu Val Cys Val Asp Met
                  95                 100                 105

 Pro Gly His Glu Gly Thr Thr Arg Ser Ser Leu Asp Asp Leu Ser
                 110                 115                 120

 Ile Asp Gly Gln Val Lys Arg Ile His Gln Phe Val Glu Cys Leu
                 125                 130                 135

 Lys Leu Asn Lys Lys Pro Phe His Leu Val Gly Thr Ser Met Gly
                 140                 145                 150

 Gly Gln Val Ala Gly Val Tyr Ala Ala Tyr Tyr Pro Ser Asp Val
                 155                 160                 165

 Ser Ser Leu Cys Leu Val Cys Pro Ala Gly Leu Gln Tyr Ser Thr
                 170                 175                 180

 Asp Asn Gln Phe Val Gln Arg Leu Lys Glu Leu Gln Gly Ser Ala
                 185                 190                 195

 Ala Val Glu Lys Ile Pro Leu Ile Pro Ser Thr Pro Glu Glu Met
                 200                 205                 210

 Ser Glu Met Leu Gln Leu Cys Ser Tyr Val Arg Phe Lys Val Pro
                 215                 220                 225

 Gln Gln Ile Leu Gln Gly Leu Val Asp Val Arg Ile Pro His Asn
                 230                 235                 240

 Asn Phe Tyr Arg Lys Leu Phe Leu Glu Ile Val Ser Glu Lys Ser
                 245                 250                 255

 Arg Tyr Ser Leu His Gln Asn Met Asp Lys Ile Lys Val Pro Thr
                 260                 265                 270

 Gln Ile Ile Trp Gly Lys Gln Asp Gln Val Leu Asp Val Ser Gly
                 275                 280                 285

 Ala Asp Asn Val Gly Gln Val Asn Cys Gln Leu Pro Gly Gly Ala
                 290                 295                 300

 Ser Gly Lys Leu Trp Ala Leu Ser Ser Asp Gly Lys Asn Pro Gly
                 305                 310                 315

 Arg Gln Pro Ser Ser
                 320

<210> 3645
<211> 2367
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1555
<223> Unknown base

<400> 3645
 gatgatccca atagcagtga tgaatctaat ggcaatgatg atgctaattc 50

 agaaagtgac aataacagca gtagccgagg agatgcttct tataactctg 100

 atgaatcaaa agataatggc aatggcagtg actcaaaagg agcagaagat 150

 gatgacagtg atagcacatc agacactaat aatagtgaca gtaatggcaa 200

 tggtaacaat gggaatgatg acaatgacaa atcagacagt ggcaaaggta 250

 aatcagatag cagtgacagt gatagtagtg atagcagcaa tagcagtgat 300

 agtagtgaca gcagtgacag tgacagcagt gatagcaaca gtagcagtga 350

 tagtgacagc agtgacagtg acagcagtga tagcagtgac agtgatagta 400

 gtgatagcag caatagcagt gacagtagtg acagcagtga tagcagtgac 450

 agtagtgata gtagtgacag cagtgacagc aagtcagaca gcagcaaatc 500

 agagagcgac agcagtgata gtgacagtaa gtcagacagc agtgacagca 550

 acagcagtga cagtagtgac aacagtgata gcagcgacag cagcaatagc 600

 agtaacagca gtgatagtag tgacagcagt gatagcagtg acagcagcag 650

 tagcagcgac agcagcaaca gcagtgatag tagtgacagt agtgacagca 700

 gcaatagcag tgagagcagt gatagtagtg acagcagtga tagtgacagc 750

 agtgatagta gtgacagcag taatagtaac agcagcgaca gtgacagcag 800

 caacagcagc gatagcagtg acagcagcaa cagcagtgac agcagtgata 850

 gcagtgacag cagcaacagc agtgacagta gcgatagcag tgacagcagc 900

 aacagcagtg acagcagtga tagcagtgac agcagtgata gtagtgacag 950

 cagcaacagc agtgatagca acgacagcag caatagcagt gacagcagtg 1000

 atagcagcga cagcagtgat agcagcaaca gcagtgatag cagtgatagc 1050

 agtgacagca gtgatagcga cagcagcaat agcagtgaca gcagtaatag 1100

 tagtgacagc agcgatagct gcaacagcag tgatagcagc gacagcagcg 1150

 atagcagtga cggcagtgat agcgacagca gcaatagaag tgacagtagt 1200

 aatagtagtg acagcagcga tagcagtgac agcagcaaca gcagtgacag 1250

 cagtgatagc agtgacagca acgaaagcag caatagcagt gacagcagtg 1300

 atagcagcaa cagcagtgac agtgacagca gtgatagcag caacagcagt 1350

 gacagcagtg atagcagcaa cagcagtgat agcagtgaaa gcagtaatag 1400

 tagtgacaac agcaatagca gtgacagcag caacagcagt gacagcagtg 1450

 atagcagtga cagcagtaat agtagtgaca gcagcaatag cagtgacagc 1500

 agcaacagca gtgacagcag tgatagcaat agcagcgaca gcagtgacag 1550

 cagcnacagc agcgatagca gtgacagcag tgatagcagt gacagcagtg 1600

 acagcagtga tagcagcgac agcagtgata gcagtgacag cagtgacagc 1650

 agtgatagca gtaatagtag tgacagcggc aacagcagtg acagcagcga 1700

 tagcagtgac agcagcgata gcagtgacag cagcgatagc agtgacagca 1750

 gtgacagcag caatagcagt gacagcagtg acagcagcga cagcagtgat 1800

 agcagtgaca gcagtgacag cagcgacagc agtgatagca gtgaaagcag 1850

 tgatagcagc gatagcagtg acagcagcga cagcagtgac agcagtgaca 1900

 gcagtgaaag cagcaacagc agtgacagca gcgacagcag tgacagcagc 1950

 gatagcagcg acagcagcga cagcagcgat agcagtgaca gcagcaatag 2000

 aagtgatagc agcgacagca gtgatagcag tgacagcagc gacagcagcg 2050

 atagcagcga cagcagcgat agtagtgata gcagtgacag cagtgacagc 2100

 agcgacagca gtgacagcag cgacagcagt gacagcagcg acagcagtga 2150

 cagcaatgaa agcagcgaca gcagtgacag cagcgatagc agtgacagca 2200

 gcaacagcag tgacagcagc gacagcagtg atagcagtga cagcacatct 2250

 gacagcaatg atgagagcga cagccagagc aagtctggta acggtaacaa 2300

 caatggaagt gacagtgaca gtgacagtga aggcagtgac agtaaccact 2350

 caaccagtga tgattag 2367

<210> 3646
<211> 2561
<212> DNA
<213> Homo sapien

<400> 3646
 gggggactcg agagctagct gagcgaatgg gccggcgact gtggagttag 50

 cgtcctcaat gtggacgccc tgagctccca ttaggagccg ctggctgcgg 100

 cagcagggga ctagcgtgaa agttggctaa aaaaaagaaa agaacatgga 150

 ggcagatata atcacaaatc ttcgatgcag gctcaaagag gctgaagaag 200

 agcgactaaa agctgcacag tatggtttac aactagtaga gagtcaaaat 250

 gaattacaga atcaattgga taaatgtcgt aatgaaatga tgaccatgac 300

 tgagagttat gaacaagaaa aatataccct tcaaagagaa gttgaactca 350

 agagtcgaat gttagaaagt ttgagctgcg aatgtgaagc tattaaacaa 400

 caacaaaaaa tgcacctgga gaaattggaa gaacaactaa gcagaagcca 450

 tggacaggaa gtgaatgaac taaaaactaa gatagaaaaa ctgaaagtgg 500

 aattagatga agccaggctt agtgaaaagc agctgaagca ccaagtagat 550

 catcagaagg aactcctctc ttgtaaatca gaggaactgc gcgtaatgtc 600

 tgaacgtgtg caggaaagca tgtcttcaga gatgctggct cttcaaattg 650

 agctgacaga aatggagagt atgaagacca ccctcaaaga agaagtgaat 700

 gaactacaat acagacaaga acagctagaa cttcttatta ctaacctaat 750

 gcgccaggta gaccggctta aagaggaaaa agaggagcga gagaaagaag 800

 cagtttctta ctataatgcc ctagagaaag ctcgtgtagc aaatcaagat 850

 cttcaggtac agttggacca ggcactccag caagccttgg atcccaatag 900

 taaaggcaac tctttgtttg cagaggtgga agatcgaagg gcagcaatgg 950

 aacgtcagct tatcagtatg aaagtcaagt atcagtcact aaagaagcaa 1000

 aatgtattta acagagaaca gatgcagaga atgaagttac aaattgccac 1050

 gttgctacag atgaaagggt ctcaaactga atttgagcag caggaacggt 1100

 tgcttgccat gttggagcag aagaatggtg aaataaaaca tcttttaggt 1150

 gaaattagaa atctggagaa atttaagaat ttatatgaca gtatggaatc 1200

 taagccttca gtcgactctg gtactctgga agataacacc tattatacag 1250

 atttacttca gatgaagctg gataacttaa acaaagaaat tgaaagcact 1300

 aaaggtgaat tgtccataca gcgaatgaaa gcattatttg agagccagcg 1350

 ggctctagat attgagcgaa aactttttgc aaatgaaaga tgcctccagc 1400

 tttcagaaag tgaaaatatg aaactgagag ctaaactaga tgaattgaaa 1450

 ctaaaatatg aacctgaaga gacagttgaa gtgcctgtac tgaaaaagag 1500

 gcgtgaggtg ctccctgtgg atataaccac cgctaaagat gcatgtgtca 1550

 acaacagtgc tctcggggga gaagtttatc gattaccgcc tcagaaagag 1600

 gagacacagt cctgccctaa cagtttagaa gataacaact tgcaattaga 1650

 aaaatcagtt tctatacaca caccagtagt cagtctctct cctcacaaaa 1700

 atctgcccgt ggatatgcag ctgaagaagg aaaagaaatg tgtgaaactc 1750

 ataggagttc ccgctgacgc tgaggcctta agtgaaagaa gtggaaacac 1800

 ccctaactct cccaggttag ctgctgaatc aaagcttcaa acagaagtta 1850

 aagaaggaaa agaaacttca agcaaattgg aaaaagaaac ttgtaagaaa 1900

 tcacacccta ttctatatgt gtcttctaaa tctactccag agacccagtg 1950

 ccctcaacag taaagacttt tctttaataa gagtacggtg ccacttgcct 2000

 caaaagttac tatggtgctt aagattgtct tgatctgaca tatatcacct 2050

 tctgggttat ttactcattg tgccaggacc tggcattttc atgtgccttt 2100

 gaccaagtgt tcagaatttg cttgactcta acctggagag cttcttaagt 2150

 gatgcccctt catggagctt ctatgacagt gaataaacta ttaattgaag 2200

 gaaaatgtta taattaatgt atctatttgc tgcattgtat atggattaaa 2250

 tgataaaaaa caagtaatct accctcagag ccatgtattt gagaatgctt 2300

 caatcatatt ttcctatgta ctttttttta taaacttagt tttagactat 2350

 gttgtaaaaa tgggaaggtt gtaaactatg ttgtaaaaat aggaaatgtg 2400

 gcttaaaata tatacattat attgtttcag gattttgtca gtgtttaaag 2450

 aaccaatgtt catctttgta tttatataca tgatttaaat tttgtctaaa 2500

 attttaaata aaactgcagt gatttatccg taaaaaaaaa aaaaaaaaaa 2550

 aaaaaaaaaa a 2561

<210> 3647
<211> 605
<212> PRT
<213> Homo sapien

<400> 3647
 Met Glu Ala Asp Ile Ile Thr Asn Leu Arg Cys Arg Leu Lys Glu
   1               5                  10                  15

 Ala Glu Glu Glu Arg Leu Lys Ala Ala Gln Tyr Gly Leu Gln Leu
                  20                  25                  30

 Val Glu Ser Gln Asn Glu Leu Gln Asn Gln Leu Asp Lys Cys Arg
                  35                  40                  45

 Asn Glu Met Met Thr Met Thr Glu Ser Tyr Glu Gln Glu Lys Tyr
                  50                  55                  60

 Thr Leu Gln Arg Glu Val Glu Leu Lys Ser Arg Met Leu Glu Ser
                  65                  70                  75

 Leu Ser Cys Glu Cys Glu Ala Ile Lys Gln Gln Gln Lys Met His
                  80                  85                  90

 Leu Glu Lys Leu Glu Glu Gln Leu Ser Arg Ser His Gly Gln Glu
                  95                 100                 105

 Val Asn Glu Leu Lys Thr Lys Ile Glu Lys Leu Lys Val Glu Leu
                 110                 115                 120

 Asp Glu Ala Arg Leu Ser Glu Lys Gln Leu Lys His Gln Val Asp
                 125                 130                 135

 His Gln Lys Glu Leu Leu Ser Cys Lys Ser Glu Glu Leu Arg Val
                 140                 145                 150

 Met Ser Glu Arg Val Gln Glu Ser Met Ser Ser Glu Met Leu Ala
                 155                 160                 165

 Leu Gln Ile Glu Leu Thr Glu Met Glu Ser Met Lys Thr Thr Leu
                 170                 175                 180

 Lys Glu Glu Val Asn Glu Leu Gln Tyr Arg Gln Glu Gln Leu Glu
                 185                 190                 195

 Leu Leu Ile Thr Asn Leu Met Arg Gln Val Asp Arg Leu Lys Glu
                 200                 205                 210

 Glu Lys Glu Glu Arg Glu Lys Glu Ala Val Ser Tyr Tyr Asn Ala
                 215                 220                 225

 Leu Glu Lys Ala Arg Val Ala Asn Gln Asp Leu Gln Val Gln Leu
                 230                 235                 240

 Asp Gln Ala Leu Gln Gln Ala Leu Asp Pro Asn Ser Lys Gly Asn
                 245                 250                 255

 Ser Leu Phe Ala Glu Val Glu Asp Arg Arg Ala Ala Met Glu Arg
                 260                 265                 270

 Gln Leu Ile Ser Met Lys Val Lys Tyr Gln Ser Leu Lys Lys Gln
                 275                 280                 285

 Asn Val Phe Asn Arg Glu Gln Met Gln Arg Met Lys Leu Gln Ile
                 290                 295                 300

 Ala Thr Leu Leu Gln Met Lys Gly Ser Gln Thr Glu Phe Glu Gln
                 305                 310                 315

 Gln Glu Arg Leu Leu Ala Met Leu Glu Gln Lys Asn Gly Glu Ile
                 320                 325                 330

 Lys His Leu Leu Gly Glu Ile Arg Asn Leu Glu Lys Phe Lys Asn
                 335                 340                 345

 Leu Tyr Asp Ser Met Glu Ser Lys Pro Ser Val Asp Ser Gly Thr
                 350                 355                 360

 Leu Glu Asp Asn Thr Tyr Tyr Thr Asp Leu Leu Gln Met Lys Leu
                 365                 370                 375

 Asp Asn Leu Asn Lys Glu Ile Glu Ser Thr Lys Gly Glu Leu Ser
                 380                 385                 390

 Ile Gln Arg Met Lys Ala Leu Phe Glu Ser Gln Arg Ala Leu Asp
                 395                 400                 405

 Ile Glu Arg Lys Leu Phe Ala Asn Glu Arg Cys Leu Gln Leu Ser
                 410                 415                 420

 Glu Ser Glu Asn Met Lys Leu Arg Ala Lys Leu Asp Glu Leu Lys
                 425                 430                 435

 Leu Lys Tyr Glu Pro Glu Glu Thr Val Glu Val Pro Val Leu Lys
                 440                 445                 450

 Lys Arg Arg Glu Val Leu Pro Val Asp Ile Thr Thr Ala Lys Asp
                 455                 460                 465

 Ala Cys Val Asn Asn Ser Ala Leu Gly Gly Glu Val Tyr Arg Leu
                 470                 475                 480

 Pro Pro Gln Lys Glu Glu Thr Gln Ser Cys Pro Asn Ser Leu Glu
                 485                 490                 495

 Asp Asn Asn Leu Gln Leu Glu Lys Ser Val Ser Ile His Thr Pro
                 500                 505                 510

 Val Val Ser Leu Ser Pro His Lys Asn Leu Pro Val Asp Met Gln
                 515                 520                 525

 Leu Lys Lys Glu Lys Lys Cys Val Lys Leu Ile Gly Val Pro Ala
                 530                 535                 540

 Asp Ala Glu Ala Leu Ser Glu Arg Ser Gly Asn Thr Pro Asn Ser
                 545                 550                 555

 Pro Arg Leu Ala Ala Glu Ser Lys Leu Gln Thr Glu Val Lys Glu
                 560                 565                 570

 Gly Lys Glu Thr Ser Ser Lys Leu Glu Lys Glu Thr Cys Lys Lys
                 575                 580                 585

 Ser His Pro Ile Leu Tyr Val Ser Ser Lys Ser Thr Pro Glu Thr
                 590                 595                 600

 Gln Cys Pro Gln Gln
                 605

<210> 3648
<211> 1347
<212> DNA
<213> Homo sapien

<400> 3648
 ggggcctggt gtgattccgt cctgcgcggt tgttctctgg agcagcgttc 50

 ttttatctcc gtccgccttc tctcctacct aagtgcgtgc cgccacccga 100

 tggaagattc gatggacatg gacatgagcc ccctgaggcc ccagaactat 150

 cttttcggtt gtgaactaaa ggccgacaaa gattatcact ttaaggtgga 200

 taatgatgaa aatgagcacc agttatcttt aagaacggtc agtttagggg 250

 ctggtgcaaa ggatgagttg cacattgttg aagcagaggc aatgaattac 300

 gaaggcagtc caattaaagt aacactggca actttgaaaa tgtctgtaca 350

 gccaacggtt tcccttgggg gctttgaaat aacaccacca gtggtcttaa 400

 ggttgaagtg tggttcaggg ccagtgcata ttagtggaca gcacttagta 450

 gctgtggagg aagatgcaga gtcagaagat gaagaggagg aggatgtgaa 500

 actcttaagt atatctggaa agcggtctgc ccctggaggt ggtagcaagg 550

 ttccacagaa aaaagtaaaa cttgctgctg atgaagatga tgacgatgat 600

 gatgaagagg atgatgatga agatgatgat gatgatgatt ttgatgatga 650

 ggaagctgaa gaaaaagcgc cagtgaagaa atctatacga gatactccag 700

 ccaaaaatgc acaaaagtca aatcagaatg gaaaagactc aaaaccatca 750

 tcaacaccaa gatcaaaagg acaagaatcc ttcaagaaac aggaaaaaac 800

 tcctaaaaca ccaaaaggac ctagttctgt agaagacatt aaagcaaaaa 850

 tgcaagcaag tatagaaaaa ggtggttctc ttcccaaagt ggaagccaaa 900

 ttcatcaatt atgtgaagaa ttgcttccgg atgactgacc aagaggctat 950

 tcaagatctc tggcagtgga ggaagtctct ttaagaaaat agtttaaaca 1000

 atttgttaaa aaattttccg tcttatttca tttctgtaac agttgatatc 1050

 tggctgtcct ttttataatg cagagtgaga actttcccta ccgtgtttga 1100

 taaatgttgt ccaggttcta ttgccaagaa tgtgttgtcc aaaatgcctg 1150

 tttagttttt aaagatggaa ctccaccctt tgcttggttt taagtatgta 1200

 tggaatgtta tgataggaca tagtagtagc ggtggtcaga catggaaatg 1250

 gtggggagac aaaaatacac atgtgaaata aaactcagta ttttaataaa 1300

 gtaaaaaaaa aaaaaaccaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 1347

<210> 3649
<211> 294
<212> PRT
<213> Homo sapien

<400> 3649
 Met Glu Asp Ser Met Asp Met Asp Met Ser Pro Leu Arg Pro Gln
   1               5                  10                  15

 Asn Tyr Leu Phe Gly Cys Glu Leu Lys Ala Asp Lys Asp Tyr His
                  20                  25                  30

 Phe Lys Val Asp Asn Asp Glu Asn Glu His Gln Leu Ser Leu Arg
                  35                  40                  45

 Thr Val Ser Leu Gly Ala Gly Ala Lys Asp Glu Leu His Ile Val
                  50                  55                  60

 Glu Ala Glu Ala Met Asn Tyr Glu Gly Ser Pro Ile Lys Val Thr
                  65                  70                  75

 Leu Ala Thr Leu Lys Met Ser Val Gln Pro Thr Val Ser Leu Gly
                  80                  85                  90

 Gly Phe Glu Ile Thr Pro Pro Val Val Leu Arg Leu Lys Cys Gly
                  95                 100                 105

 Ser Gly Pro Val His Ile Ser Gly Gln His Leu Val Ala Val Glu
                 110                 115                 120

 Glu Asp Ala Glu Ser Glu Asp Glu Glu Glu Glu Asp Val Lys Leu
                 125                 130                 135

 Leu Ser Ile Ser Gly Lys Arg Ser Ala Pro Gly Gly Gly Ser Lys
                 140                 145                 150

 Val Pro Gln Lys Lys Val Lys Leu Ala Ala Asp Glu Asp Asp Asp
                 155                 160                 165

 Asp Asp Asp Glu Glu Asp Asp Asp Glu Asp Asp Asp Asp Asp Asp
                 170                 175                 180

 Phe Asp Asp Glu Glu Ala Glu Glu Lys Ala Pro Val Lys Lys Ser
                 185                 190                 195

 Ile Arg Asp Thr Pro Ala Lys Asn Ala Gln Lys Ser Asn Gln Asn
                 200                 205                 210

 Gly Lys Asp Ser Lys Pro Ser Ser Thr Pro Arg Ser Lys Gly Gln
                 215                 220                 225

 Glu Ser Phe Lys Lys Gln Glu Lys Thr Pro Lys Thr Pro Lys Gly
                 230                 235                 240

 Pro Ser Ser Val Glu Asp Ile Lys Ala Lys Met Gln Ala Ser Ile
                 245                 250                 255

 Glu Lys Gly Gly Ser Leu Pro Lys Val Glu Ala Lys Phe Ile Asn
                 260                 265                 270

 Tyr Val Lys Asn Cys Phe Arg Met Thr Asp Gln Glu Ala Ile Gln
                 275                 280                 285

 Asp Leu Trp Gln Trp Arg Lys Ser Leu
                 290

<210> 3650
<211> 2844
<212> DNA
<213> Homo sapien

<400> 3650
 acccaaccct gtcattattt cccctccgac tgggccggtg ccatcggaaa 50

 ccggagtgac cagaggaggg acacgcatcc aatttcactg ggctgcaaga 100

 tatcaataag ccttgcctct ttaaactact tatgtacaaa taaaagtgat 150

 ggtgagaacc tggctcagga aatgcagtag caggccatat tgcatccaaa 200

 ggaattactc acagctgtgc tgtgtgcatt ctctgtgggc ctagcaggga 250

 aggggacagc cctgtggcaa tgggcatgac acggatgctc ctggaatgca 300

 gtctcagtga caagttgtgt gtcatccagg agaagcagta tgaagtgatt 350

 atcgtcccaa ctttgttggt tactatcttc ctcatccttc ttggggtcat 400

 cctgtggctt tttatcagag aacaaagaac tcaacagcag cgttctggac 450

 ctcaaggcat tgcccctgtt cctccaccta gggacctaag ctgggaagca 500

 ggacatggag gaaatgtggc tttgccactt aaggagacat ccgtggaaaa 550

 ctttctggga gctaccacac ctgccctggc taagctgcag gtgccgcggg 600

 agcaactctc tgaagttctg gagcagattt gcagtggtag ctgtgggccc 650

 atctttcgag ccaatatgaa cactggggac ccttctaagc ccaagagtgt 700

 tattctcaag gctttaaaag aaccagctgg gctccatgag gtacaagatt 750

 tcttagggcg aatccaattc catcaatacc tggggaaaca caaaaacctg 800

 gtgcagctgg aaggctgctg cactgaaaag ctgccactct atatggtgtt 850

 ggaggatgtg gcccaggggg acctgctcgg ctttctctgg acctgtcggc 900

 gggatgtgat gactatggat ggtcttctct atgatctcac agaaaaacaa 950

 gtatatcaca tcggaaagca ggtccttttg gcgctggaat tcctgcagga 1000

 gaagcatttg ttccatgggg atgtggcagc caggaatatt ctgatgcaaa 1050

 gtgatctcac tgctaagctc tgtggattag gcctggctta tgaagtttac 1100

 acccgagggg ccatctcctc tactcaaacc atacctctca agtggcttgc 1150

 cccagaacgg cttctcctga gacctgctag catcagagca gatgtctggt 1200

 cttttgggat cctgctctat gagatggtga ctctaggagc accaccgtat 1250

 cctgaagtcc ctcctaccag catcctagag catctccaaa gaaggaaaat 1300

 catgaagaga cccagtagct gcacacatac catgtacagt atcatgaagt 1350

 cctgctggcg ctggcgtgag gctgaccgcc cctcacctag agagctgcgc 1400

 ttgcgcctag aagctgccat taaaactgca gatgacgagg ctgtgttaca 1450

 agtaccagag ttggtggtac ctgaactgta tgcagctgtg gccggcatca 1500

 gagtggagag cctcttctac aactatagca tgctttgaag agtctcgggc 1550

 aagaaacatt catgcatgag tatatgttct tggaatcaat tcctctaaga 1600

 acagagaatg gtctttccca gggacacaaa gggagaaatg ggacatggat 1650

 tcttgatctt cctttacaca tttctcggga aatctgaaat gatgctggat 1700

 gggactctac acatcctgag ctaagacata ctgtcagtct cacttctgct 1750

 gtcccagtcc tagaaatcct gggtagaagt ggtggacctg tgcaaaggag 1800

 gttttagaac tctgcagtat ttgttggggc atggcacaaa taagctcatc 1850

 cctcccgtcc gaggctagtt tcctctggaa ccacattttt atctagatga 1900

 aaatttggaa tgaaatgaag gaatagaaat ccaataaaag agttgaaggg 1950

 aaagaaaatt taaggttctt cttgctcagg attacagata tggaccaaca 2000

 cctccttcaa gaaaaggtgg taggacacaa agttcttcag tcctgagccc 2050

 tacatgtggg gttggaggag aactataacg gaaaaacctc tgagtttcac 2100

 cttaggtata gataaaagaa agatggtccc cttttatctg attctgagac 2150

 aggtaaattc tgtttgttac tacgtttaat tagaaggtgg aggagtcatt 2200

 tcatgattaa gaacattcaa catgtattgt tcattaagct agcttcctag 2250

 ttccgattag actaaggaga ctaagcctag agagtcaatg ttagaacagt 2300

 gaaaagaatt ctgtgtgtgt gtgtgtgtgt gtgcacaata aataggaaat 2350

 gtagaaacca agcaagaagg cttagtagct cagtctttaa caagggctag 2400

 aaaagaatgt aatctgatat ggaaggatag cagcttctaa ttttcaatca 2450

 tctgttgata tactgtgaaa cttattttat taaattaata tttattaaat 2500

 ggaaatatgc ttttctggtt tataactact aaaaatatca tagggaggat 2550

 aaaagtaaat aagtgaaagt taatgccaat agaaaaattc aagagataat 2600

 gtacaatgtc agaaaaggga ttctttatgt gtaaatgggg ataataccta 2650

 tttcacaagg ttgttctgag gattgatacg ttttgagtat gtatttgtac 2700

 actatctggc acatatgcgc tcaataaacg tgtttctcct tttaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 2844

<210> 3651
<211> 422
<212> PRT
<213> Homo sapien

<400> 3651
 Met Gly Met Thr Arg Met Leu Leu Glu Cys Ser Leu Ser Asp Lys
   1               5                  10                  15

 Leu Cys Val Ile Gln Glu Lys Gln Tyr Glu Val Ile Ile Val Pro
                  20                  25                  30

 Thr Leu Leu Val Thr Ile Phe Leu Ile Leu Leu Gly Val Ile Leu
                  35                  40                  45

 Trp Leu Phe Ile Arg Glu Gln Arg Thr Gln Gln Gln Arg Ser Gly
                  50                  55                  60

 Pro Gln Gly Ile Ala Pro Val Pro Pro Pro Arg Asp Leu Ser Trp
                  65                  70                  75

 Glu Ala Gly His Gly Gly Asn Val Ala Leu Pro Leu Lys Glu Thr
                  80                  85                  90

 Ser Val Glu Asn Phe Leu Gly Ala Thr Thr Pro Ala Leu Ala Lys
                  95                 100                 105

 Leu Gln Val Pro Arg Glu Gln Leu Ser Glu Val Leu Glu Gln Ile
                 110                 115                 120

 Cys Ser Gly Ser Cys Gly Pro Ile Phe Arg Ala Asn Met Asn Thr
                 125                 130                 135

 Gly Asp Pro Ser Lys Pro Lys Ser Val Ile Leu Lys Ala Leu Lys
                 140                 145                 150

 Glu Pro Ala Gly Leu His Glu Val Gln Asp Phe Leu Gly Arg Ile
                 155                 160                 165

 Gln Phe His Gln Tyr Leu Gly Lys His Lys Asn Leu Val Gln Leu
                 170                 175                 180

 Glu Gly Cys Cys Thr Glu Lys Leu Pro Leu Tyr Met Val Leu Glu
                 185                 190                 195

 Asp Val Ala Gln Gly Asp Leu Leu Gly Phe Leu Trp Thr Cys Arg
                 200                 205                 210

 Arg Asp Val Met Thr Met Asp Gly Leu Leu Tyr Asp Leu Thr Glu
                 215                 220                 225

 Lys Gln Val Tyr His Ile Gly Lys Gln Val Leu Leu Ala Leu Glu
                 230                 235                 240

 Phe Leu Gln Glu Lys His Leu Phe His Gly Asp Val Ala Ala Arg
                 245                 250                 255

 Asn Ile Leu Met Gln Ser Asp Leu Thr Ala Lys Leu Cys Gly Leu
                 260                 265                 270

 Gly Leu Ala Tyr Glu Val Tyr Thr Arg Gly Ala Ile Ser Ser Thr
                 275                 280                 285

 Gln Thr Ile Pro Leu Lys Trp Leu Ala Pro Glu Arg Leu Leu Leu
                 290                 295                 300

 Arg Pro Ala Ser Ile Arg Ala Asp Val Trp Ser Phe Gly Ile Leu
                 305                 310                 315

 Leu Tyr Glu Met Val Thr Leu Gly Ala Pro Pro Tyr Pro Glu Val
                 320                 325                 330

 Pro Pro Thr Ser Ile Leu Glu His Leu Gln Arg Arg Lys Ile Met
                 335                 340                 345

 Lys Arg Pro Ser Ser Cys Thr His Thr Met Tyr Ser Ile Met Lys
                 350                 355                 360

 Ser Cys Trp Arg Trp Arg Glu Ala Asp Arg Pro Ser Pro Arg Glu
                 365                 370                 375

 Leu Arg Leu Arg Leu Glu Ala Ala Ile Lys Thr Ala Asp Asp Glu
                 380                 385                 390

 Ala Val Leu Gln Val Pro Glu Leu Val Val Pro Glu Leu Tyr Ala
                 395                 400                 405

 Ala Val Ala Gly Ile Arg Val Glu Ser Leu Phe Tyr Asn Tyr Ser
                 410                 415                 420

 Met Leu


<210> 3652
<211> 2738
<212> DNA
<213> Homo sapien

<400> 3652
 gtcacgtgtc ccccccgcgg ggggcggccc ttgagggcgg cgcttccggt 50

 cggcggagcc tggtggccgc agcggcggtg gcgacgacgg ccgagacgtg 100

 gggatggcgg gcgccgggag cgaagcccgg ttcgccgggc tgtcgctggt 150

 gcagctcaac gagctgctgg aggacgaggg ccagctgacg gagatggtgc 200

 agaagatgga ggagacacag aatgttcagc ttaacaaaga aatgacactt 250

 gccagcaacc ggagcctggc agaaggaaac cttttgtacc agccccagct 300

 ggacacgttg aaagcacgct tgacccagaa ataccaggaa ctccaggttc 350

 tctttgaagc ctatcagata aagaagacca aattagacag acagtctagc 400

 agtgcttcct tggagaccct gttagcactt cttcaggcag aaggggccaa 450

 gattgaggaa gacactgaga acatggcaga gaagtttctg gatggagaac 500

 ttcctctgga ttccttcatt gatgtctatc agagcaaacg gaaactggcc 550

 cacatgcgac gggtgaaaat cgagaagctc caggagatgg tcctaaaggg 600

 gcagagactc ccacaggccc tggccccgct gccccccagg ctgcccgaac 650

 tggcacctac cgcccccctt ccctaccctg ccccagaggc cagtgggcct 700

 cctgccgttg cacctcggcg catccccccc ccaccacccc cggtgcctgc 750

 gggacgctta gccaccccgt ttactgcggc catgagttcg ggacaggccg 800

 tgccgtaccc aggattacag tgcccgcccc tgcccccccg cgtgggcctc 850

 cccactcagc aaggattctc ttcgcagttc gtgtccccat atccgccacc 900

 tctccctcag agacccccgc cccggctccc tccacaccag ccgggtttca 950

 tcctccagtg agcgccggcg cggtccttcc cgggagactt cttccacctg 1000

 gcgtgttgtg ctctgctcac gggaaggagg ctggaggtcc gctctgtgcc 1050

 aagggctctg gggccctggg ccagcgtgtc tgtctgattt tagaactgta 1100

 ggtcagtggt gagtagtagg agcccaggct ttgggcatca aggcagttgt 1150

 gtgtgccggg ttacagcctg acacctgtgc gttgcatcgg tttgcattat 1200

 ccgtgtgatt tctaagtatc ttagcgttga tgaactcatg tttgggaaga 1250

 aataggcctc tcccccagtc ccatttagaa tcgtggtcct tctgttgcag 1300

 ctttatttaa tgagcatggt tcatgatact tattttattt tcgaaagaca 1350

 gtcctatgtg tctcacccac cggccactgc agccctggtg agggcgggtg 1400

 ggcgccggcc ggcctggaag agcgccgtgg ctgggccacc acctgtggct 1450

 gcgttgttgc tcactgaatc tgttggggag aggtcaccat agtcaccgcc 1500

 tgacctggct gctgctcttg cttcagagcc acaagcaaag tttgcactgg 1550

 gcccactgcc gagtccagag gccggagaac ggccactggt gtgggagggg 1600

 agcgcacgag tgggactttg cacagcaaat tgtgtcccca gctcctcctc 1650

 tcccgcctgc ctggagccgg ccctgaaggt ttctatgaag aaataatccc 1700

 ccaatatttt tactacgtgt gtgattttcc tgttttatat tgaaaaaact 1750

 tttttgacac tcccaagacc attcagggaa attttataaa aaatgcagat 1800

 actgtcttga gcagatcgaa atgccgatga agtggatgca atttcctttt 1850

 gtgcaagcag tgcacggtgc ccccccctcg ggtgtccgtg ctgtgcctta 1900

 gcttccccag gtgccgggac tcacacctgc taggggctgg gcaaggcccc 1950

 ggctctgctt tctctgaagg gcttgtccaa gttcattgcc ctgttacagg 2000

 tggtcaagac gtccggccgc cttgacccag gctaccctta gccaatatcc 2050

 tctgcccctg ggtggctggt ggctgggcct cagggtgggc aacgttaggg 2100

 gtttggcgaa agcccgcccc atgggattga gggacggggc tgcactccaa 2150

 ccgtctgcac ctgctcttcc cccacccctg tgggacctca tcttcacgtg 2200

 ccatgtgtgc tgaaggccca gggcccagca gggggcagtg gcacctgttg 2250

 acggaaaagg ccgaggtgct taccagtgga ccttctggcc cgcccctccc 2300

 ctgtcacttg tcgggcatcc agggccccga cctgtgccta gccgccaggg 2350

 tgacagaagg cagaactgaa gcggggtctg ggccacgggc caggccactg 2400

 ccttttgtcc tcagtgacca tacattcctg ctctcggact tgaactctac 2450

 tgtaactgtt ttcttgaaat gaagctgtac aggacgattc actgccatgc 2500

 cagtcaggcg ggcttgccat gttctgtgaa tctcgagtga gcggtgccac 2550

 ccgcccccat acctccgcca ccggccgctg tcggggatgc cacagcctgc 2600

 cacggtcgca gccagacgtg agcttggcat tgaagttgca aagcggcccc 2650

 tggccgggct cgccgtcgct gtccagggcc gtgtccggtg ctgtggctgt 2700

 aaagctgtag gacccttttt aataaataga gaattatt 2738

<210> 3653
<211> 285
<212> PRT
<213> Homo sapien

<400> 3653
 Met Ala Gly Ala Gly Ser Glu Ala Arg Phe Ala Gly Leu Ser Leu
   1               5                  10                  15

 Val Gln Leu Asn Glu Leu Leu Glu Asp Glu Gly Gln Leu Thr Glu
                  20                  25                  30

 Met Val Gln Lys Met Glu Glu Thr Gln Asn Val Gln Leu Asn Lys
                  35                  40                  45

 Glu Met Thr Leu Ala Ser Asn Arg Ser Leu Ala Glu Gly Asn Leu
                  50                  55                  60

 Leu Tyr Gln Pro Gln Leu Asp Thr Leu Lys Ala Arg Leu Thr Gln
                  65                  70                  75

 Lys Tyr Gln Glu Leu Gln Val Leu Phe Glu Ala Tyr Gln Ile Lys
                  80                  85                  90

 Lys Thr Lys Leu Asp Arg Gln Ser Ser Ser Ala Ser Leu Glu Thr
                  95                 100                 105

 Leu Leu Ala Leu Leu Gln Ala Glu Gly Ala Lys Ile Glu Glu Asp
                 110                 115                 120

 Thr Glu Asn Met Ala Glu Lys Phe Leu Asp Gly Glu Leu Pro Leu
                 125                 130                 135

 Asp Ser Phe Ile Asp Val Tyr Gln Ser Lys Arg Lys Leu Ala His
                 140                 145                 150

 Met Arg Arg Val Lys Ile Glu Lys Leu Gln Glu Met Val Leu Lys
                 155                 160                 165

 Gly Gln Arg Leu Pro Gln Ala Leu Ala Pro Leu Pro Pro Arg Leu
                 170                 175                 180

 Pro Glu Leu Ala Pro Thr Ala Pro Leu Pro Tyr Pro Ala Pro Glu
                 185                 190                 195

 Ala Ser Gly Pro Pro Ala Val Ala Pro Arg Arg Ile Pro Pro Pro
                 200                 205                 210

 Pro Pro Pro Val Pro Ala Gly Arg Leu Ala Thr Pro Phe Thr Ala
                 215                 220                 225

 Ala Met Ser Ser Gly Gln Ala Val Pro Tyr Pro Gly Leu Gln Cys
                 230                 235                 240

 Pro Pro Leu Pro Pro Arg Val Gly Leu Pro Thr Gln Gln Gly Phe
                 245                 250                 255

 Ser Ser Gln Phe Val Ser Pro Tyr Pro Pro Pro Leu Pro Gln Arg
                 260                 265                 270

 Pro Pro Pro Arg Leu Pro Pro His Gln Pro Gly Phe Ile Leu Gln
                 275                 280                 285

<210> 3654
<211> 10156
<212> DNA
<213> Homo sapien

<400> 3654
 gcggccgctc ccccggagcg gctaaagcgg cggcgaccga ggcgagcaat 50

 gggcacggca gtctcggcag agcacaggcg cttcaccgcg gctgctcggg 100

 ctccgcgctg acctgcccgg gcggccgcct attgtctttc tccgcggcga 150

 aggtgaagag ttgtcccagc tcggcccgcg ggggagcccc gggagccgca 200

 cgtgtcctgg gtcatgaaac ttaatccaca gcaagctccc ttatatggtg 250

 attgtgttgt tacagtgctg cttgctgaag aggacaaagc tgaagatgat 300

 gtagtgtttt acttggtatt tttgggttcc accctccgtc actgtacaag 350

 tactcggaag gtcagttctg atacattgga gaccattgct cctggtcatg 400

 attgttgtga aacagtgaag gtgcagctct gtgcttccaa agagggcctt 450

 cccgtgtttg tggtggctga agaagacttt catttcgtcc aggatgaagc 500

 gtatgatgca gctcaattcc tagcaaccag tgctggaaat cagcaggctt 550

 tgaactttac ccgttttctt gaccagtcag gacccccatc tggggatgtg 600

 aattcccttg ataagaagtt ggtgctggca ttcaggcacc tgaagctgcc 650

 cacggagtgg aatgtattgg ggacagatca gagtttgcat gatgctggcc 700

 cgcgagagac attgatgcat tttgctgtgc ggctgggact gctgaggttg 750

 acgtggttcc tgttgcagaa gccaggtggc cgcggagctc tcagtatcca 800

 caaccaggaa ggggcgacgc ctgtgagctt ggccttggag cgaggctatc 850

 acaagctgca ccagcttcta accgaggaga atgctggaga accagactcc 900

 tggagcagtt tatcctatga aataccgtat ggagactgtt ctgtgaggca 950

 tcatcgagag ttggacatct atacattaac ctctgagtct gattcacatc 1000

 atgaacaccc atttcctgga gacggttgca ctggaccaat ttttaaactt 1050

 atgaacatcc aacagcaact aatgaaaaca aacctcaagc agatggacag 1100

 tcttatgccc ttaatgatga cagcacagga tccttccagt gccccagaga 1150

 cagatggcca gtttcttccc tgtgcaccgg agcccacgga ccctcagcga 1200

 ctttcttctt ctgaagagac tgagagcact cagtgctgcc cagggagccc 1250

 tgttgcacag actgaaagtc cctgtgattt gtcaagcata gttgaggagg 1300

 agaatacaga ccgttcctgt aggaagaaaa ataaaggcgt ggaaagaaaa 1350

 ggggaagagg tggagccagc acctattgtg gactctggaa ctgtatctga 1400

 tcaagacagc tgccttcaga gcttgcctga ttgtggagta aagggcacgg 1450

 aaggcctttc gtcctgtgga aacagaaatg aagaaactgg aacaaaatct 1500

 tctggaatgc ccacagacca ggagtccctg agcagtggag atgctgtgct 1550

 tcagagagac ttggtcatgg agccaggcac agcccagtat tcctctggag 1600

 gtgaactggg aggcatttca acaacaaatg tcagtacccc agacactgca 1650

 ggggaaatgg aacatgggct catgaaccca gatgccactg tttggaagaa 1700

 tgtgcttcag ggaggggaaa gtacaaagga aagatttgag aactctaata 1750

 ttggcacagc tggagcctct gacgtgcacg tcacaagtaa gcctgtggat 1800

 aaaatcagtg ttccaaactg tgcccctgct gccagttccc tggatggtaa 1850

 caaacctgct gagtcttcac ttgcatttag taatgaagaa acctccactg 1900

 aaaaaacagc agaaacggaa acttcacgaa gtcgtgagga gagtgctgat 1950

 gctccagtag atcagaattc tgtggtgatt ccagctgctg caaaagacaa 2000

 gatttcagat ggattagaac cttatactct cttagcagca ggcataggtg 2050

 aggcaatgtc accctcagat ttagcccttc ttgggctgga agaagatgta 2100

 atgccacacc agaactcaga aacaaattca tctcatgctc aaagccaaaa 2150

 gggcaaatcc tcacccattt gttctacaac tggagacgat aaactttgtg 2200

 cagactctgc atgtcaacag aacacagtga cttctagtgg cgatttggtt 2250

 gcaaaactgt gtgataacat agttagcgag tccgaaagca ccacagcaag 2300

 gcaacccagc tcacaagatc cacccgatgc ctcccactgt gaagacccac 2350

 aggctcatac agtcacctct gaccctgtaa gggataccca ggaacgtgcg 2400

 gatttttgtc ctttcaaagt ggtggataac aaaggccaac gaaaagatgt 2450

 gaaactagat aaacctttaa caaatatgct tgaggtggtt tcacatccac 2500

 atccagttgt ccctaaaatg gagaaagaac tggtgccaga ccaggcagta 2550

 atatcagaca gtactttctc tctggcaaac agtccaggca gtgaatcagt 2600

 aaccaaggat gacgcacttt cttttgtccc ctcccagaaa gaaaagggaa 2650

 cagcaactcc tgaactacat acagctacag attatagaga tggcccagat 2700

 ggaaattcga atgagcctga tacgcggcca ctagaagaca gggcagtagg 2750

 cctgtccaca tcctccactg ctgcagagct tcagcacggg atggggaata 2800

 ccagtctcac aggacttggt ggagagcatg agggtcccgc ccctccagca 2850

 atcccagaag ctctgaatat caaggggaac actgactctt ccctgcaaag 2900

 tgtgggtaag gccactttgg ctttagattc agttttgact gaagaaggaa 2950

 aacttctggt ggtttcagaa agctctgcag ctcaggaaca agataaggat 3000

 aaagcggtga cctgttcctc tattaaggaa aatgctctct cttcaggaac 3050

 tttgcaggaa gagcagagaa caccacctcc tggacaagat actcaacaat 3100

 ttcatgaaaa atcaatctca gctgactgtg ccaaggacaa agcacttcag 3150

 ctaagtaatt caccgggtgc atcctctgcc tttcttaagg cagaaactga 3200

 acataacaag gaagtggccc cacaagtctc actgctgact caaggtgggg 3250

 ctgcccagag cctggtgcca ccaggagcaa gtctggccac agagtcaagg 3300

 caggaagcct tgggggcaga gcacaacagc tccgctctgt tgccatgtct 3350

 gttgccagat gggtctgatg ggtccgatgc tcttaactgc agtcagcctt 3400

 ctcctctgga tgttggagtg aagaacactc aatcccaggg aaaaactagt 3450

 gcctgtgagg tgagtggaga tgtgacggtg gatgttacag gggttaatgc 3500

 tctacaaggt atggctgagc ccagaagaga gaatatatca cacaacaccc 3550

 aagacatcct gattccaaac gtcttgttga gccaagagaa gaatgccgtt 3600

 ctaggtttgc cagtggctct acaggacaaa gctgtgactg acccacaggg 3650

 agttggaacc ccagagatga tacctcttga ttgggagaaa gggaagctgg 3700

 agggagcaga ccacagctgt accatgggtg acgctgagga agcccaaata 3750

 gacgatgaag cacatcctgt cctactgcag cctgttgcca aggagctccc 3800

 cacagacatg gagctctcag cccatgatga tggggcccca gctggtgtga 3850

 gggaagtcat gcgagccccg ccttcaggca gggaaaggag cactccctct 3900

 ctaccttgca tggtctctgc ccaggacgca cctctgccta agggggcaga 3950

 cttgatagag gaggctgcca gccgtatagt ggatgctgtc atcgaacaag 4000

 tcaaggccgc tggagcactg cttactgagg gggaggcctg tcacatgtca 4050

 ctgtccagcc ctgagttggg tcctctcact aaaggactag agagtgcttt 4100

 tacagaaaaa gtgagtactt tcccacctgg ggagagccta ccaatgggca 4150

 gtactcctga ggaagccacg gggagccttg caggatgttt tgctggaagg 4200

 gaggagccag agaagatcat tttacctgtc caggggcctg agccagcagc 4250

 agaaatgcca gacgtgaaag ctgaagatga agtggatttt agagcaagtt 4300

 caatttctga agaagtggct gtagggagca tagctgctac actgaagatg 4350

 aagcaaggcc caatgaccca ggcgataaac cgagaaaact ggtgtacaat 4400

 agagccatgc cctgatgcag catctcttct ggcttccaag cagagcccag 4450

 aatgtgagaa cttcctggat gttggactgg gcagagagtg tacctcaaaa 4500

 caaggtgtac ttaaaagaga atctgggagt gattctgacc tctttcactc 4550

 acccagtgat gacatggaca gcatcatctt cccaaagcca gaggaagagc 4600

 atttggcctg tgatatcacc ggatccagtt catccaccga tgacacggct 4650

 tcactggacc gacattcttc tcatggcagt gatgtgtctc tctcccagat 4700

 tttaaagcca aacaggtcaa gagatcggca aagccttgat ggattctaca 4750

 gccatgggat gggagctgag ggtcgagaaa gtgagagtga gcctgctgac 4800

 ccaggcgacg tggaggagga ggagatggac agtatcactg aagtgcctgc 4850

 aaactgctct gtcctaagga gctccatgcg ctctctttct cccttccgga 4900

 ggcacagctg ggggcctggg aaaaatgcag ccagcgatgc agaaatgaac 4950

 caccggagtt caatgcgagt tcttggggat gttgtcagga gacctcccat 5000

 tcataggaga agtttcagtc tagaaggctt gacaggagga gctggtgtcg 5050

 gaaacaagcc atcctcatct ctagaagtaa gctctgcaaa tgccgaagag 5100

 ctcagacacc cattcagtgg tgaggaacgg gttgactctt tggtgtcact 5150

 ttcagaagag gatctggagt cagaccagag agaacatagg atgtttgatc 5200

 agcagatatg tcacagatct aagcagcagg gatttaatta ctgtacatca 5250

 gccatttcct ctccattgac aaaatccatc tcattaatga caatcagcca 5300

 tcctggattg gacaattcac ggcccttcca cagtaccttc cacaatacca 5350

 gtgctaatct gactgagagt ataacagaag agaactataa tttcctgcca 5400

 catagcccct ccaagaaaga ttctgaatgg aagagtggaa caaaagtcag 5450

 tcgtacattc agctacatca agaataaaat gtctagcagc aagaagagca 5500

 aagaaaagga aaaagaaaaa gataagatta aggagaagga gaaagattct 5550

 aaagacaagg agaaagataa gaagactgtc aacgggcaca ctttcagttc 5600

 cattcctgtt gtgggtccca tcagctgtag ccagtgtatg aagcccttca 5650

 ccaacaaaga tgcctatact tgtgcaaatt gcagtgcttt tgtccacaaa 5700

 ggctgccgag aaagtctagc ctcctgtgca aaggtcaaaa tgaagcagcc 5750

 caaagggagc cttcaggcac atgacacatc atcactgccc acggtcatta 5800

 tgagaaacaa gccctcacag cccaaggagc gtcctcggtc cgcagtcctc 5850

 ctggtggatg aaaccgctac caccccaata tttgccaata gacgatccca 5900

 gcagagtgtc tcgctctcca aaagtgtctc catacagaac attactggag 5950

 ttggcaatga tgagaacatg tcaaacacct ggaaattcct gtctcattca 6000

 acagactcac taaataaaat cagcaaggtc aatgagtcaa cagaatcact 6050

 tactgatgag ggagtaggta cagacatgaa tgaaggacaa ctactgggag 6100

 actttgagat tgagtccaaa cagctggaag cagagtcttg gagtcggata 6150

 atagacagca agtttctaaa acagcaaaag aaagatgtgg tcaaacggca 6200

 agaagtaata tatgagttga tgcagacaga gtttcatcat gtccgcactc 6250

 tcaagatcat gagtggtgtg tacagccagg ggatgatggc ggatctgctt 6300

 tttgagcagc agatggtaga aaagctgttc ccctgtttgg atgagctgat 6350

 cagtatccat agccaattct tccagaggat tctggagcgg aagaaggagt 6400

 ctctggtgga taaaagtgaa aagaactttc tcatcaagag gataggggat 6450

 gtgcttgtaa atcagttttc aggtgagaat gcagaacgtt taaagaagac 6500

 atatggcaag ttttgtgggc aacataacca gtctgtaaac tacttcaaag 6550

 acctttatgc caaggataag cgttttcaag cctttgtaaa gaagaagatg 6600

 agcagttcag ttgttagaag gcttggaatt ccagagtgca tattgcttgt 6650

 aactcagcgg attaccaagt acccagtttt attccaaaga atattgcagt 6700

 gtaccaaaga caatgaagtg gagcaggaag atctagcaca gtccttgagc 6750

 ctggtgaagg atgtgattgg agctgtagac agcaaagtgg caagttatga 6800

 aaagaaagtg cgtctcaatg agatttatac aaagacagat agcaagtcaa 6850

 tcatgaggat gaagagtggt cagatgtttg ccaaggaaga tttgaaacgg 6900

 aagaagcttg tacgtgatgg gagtgtgttt ctgaagaatg cagcaggaag 6950

 gttgaaagag gttcaagcag ttcttctcac tgacatttta gttttccttc 7000

 aagaaaaaga ccagaagtac atctttgcat cattggacca gaagtcaaca 7050

 gtgatctctt taaagaagct gattgtgaga gaagtggcac atgaggagaa 7100

 aggtttattc ctgatcagca tggggatgac agatccagag atggtagaag 7150

 tccatgccag ctccaaagag gaacgaaaca gctggattca gatcattcag 7200

 gacacaatca acaccctgaa cagagatgaa gatgaaggaa ttcctagtga 7250

 gaatgaggaa gaaaagaaaa tgttggacac cagagcccga gaattaaaag 7300

 aacaacttca ccagaaggac caaaaaatcc tactcttgtt ggaagagaag 7350

 gagatgattt tccgggacat ggctgagtgc agcacccctc tcccagagga 7400

 ttgctcccca acacatagcc ctagagttct cttccgctcc aacacagaag 7450

 aggctctcaa aggaggacct ttaatgaaaa gtgcaataaa tgaggtggag 7500

 atccttcagg gtttggtgag tggaaatctg ggaggcacac ttgggccgac 7550

 tgtcagcagc cccattgagc aagatgtggt cggtcccgtt tccctgcccc 7600

 ggagagcaga gacctttgga ggatttgaca gccatcagat gaatgcttca 7650

 aaaggaggcg agaaggaaga gggagatgat ggccaagatc ttaggagaac 7700

 ggaatcagat agtggcctaa aaaagggtgg aaatgctaac ctggtattta 7750

 tgcttaaaag aaacagtgag caggttgtcc agagcgttgt tcatctctac 7800

 gagctcctca gcgctctgca gggtgtggtg ctgcagcagg acagctacat 7850

 tgaggaccag aaactggtgc tgagcgagag ggcgctcact cgcagcttgt 7900

 cccgcccgag ctccctcatt gagcaggaga agcagcgcag cctggagaag 7950

 cagcgccagg acctggccaa cctgcagaag cagcaggccc agtacctcga 8000

 ggagaagcgc aggcgcgagc gtgagtggga agctcgtgag agggagctgc 8050

 gggagcggga ggccctcctg gcccagcgcg aggaggaggt gcagcagggg 8100

 cagcaggacc tggaaaagga gcgggaggag ctccagcaga agaagggcac 8150

 ataccagtat gacctggagc gactgcgtgc tgcccagaaa cagcttgaga 8200

 gggaacagga gcagctgcgc cgggaggcag agcggctcag ccagcggcag 8250

 acagaacggg acctgtgtca ggtttcccat ccacatacca agctgatgag 8300

 gatcccatcg ttcttcccca gtcctgagga gcccccctcg ccatctgcac 8350

 cttccatagc caaatcaggg tcattggact cagaactttc agtgtcccca 8400

 aaaaggaaca gcatctctcg gacacacaaa gataaggggc cttttcacat 8450

 actgagttca accagccaga caaacaaagg accagaaggg cagagccagg 8500

 cccctgcgtc cacctctgcc tctacccgcc tgtttgggtt aacaaagcca 8550

 aaggaaaaga aggagaaaaa aaagaagaac aaaaccagcc gctctcagcc 8600

 cggtgatggt cccgcgtcag aagtatcagc agagggtgaa gagatcttct 8650

 gctgaccctc ttcctctctg ctgaggcagc tgcctcctga tcctggccag 8700

 cccacctctc ctgctgtccc cgcgtgcaca agtctcttac actggacgcc 8750

 cactgctcct cagcgtccag tcctcctggg cggccccagg tcctggacaa 8800

 taagcaacag atgatattga gtgtcgggtg gggaaggagg cccagactct 8850

 gcttcggcca tgatttgtga ctgcccagga ctctcaggtt gggctggccc 8900

 tactcaggat tacactgaaa gtaatggcct cgtaagtaca ggtgatggtt 8950

 ttggacacgt caggaattcc taaaggctga aagagtgtat ccaagtaagg 9000

 tctgaacctc cgactgcctt ttatttgggg gaacacaaaa ccaaacagca 9050

 gatgttttgg acttgatctg tgtacgtaca tggggacctg tctgcatata 9100

 cacacgggga atgccagaag aaggcccagt ctgcaccagg cgtctggtca 9150

 acttagcaca agggcagtgc ctggacggac ccggagcccc cgcatatcag 9200

 cagttcaccc agtactcctc agagactggt ttccctctaa acccatcccg 9250

 ggcacatacc acccctgttt tgcatgtatt tctcatttca ttttagggat 9300

 gacaaacatt tgtgaaacca gtgagagaag gcttgatgtg tataaaagac 9350

 gtgatgtgca ccacctcgat ctcggtgttt caggcactaa agcaacaaaa 9400

 caacccatag tatctcattt tgtcatcaga tccagaagaa atatcctggt 9450

 tttccagcat gtttacccac atgttttggg catggataaa gtgaagaggc 9500

 ctactcacca ttatccctgc agcgtgacac cttttgattg tcactgacca 9550

 ctcagaaggg gccacggcct cctggctgtg ttcctgagcc cccgtcgtgc 9600

 ctctcccaga cagcagctgt ctggcccttg ctgggtgagg gcacaccact 9650

 gccaggggtc agcctcgcac ccaggccagg cagaagctgt gctctgaagc 9700

 taggacagct ggctgagaag tgggttcagg cgaagggtga agccatgtgt 9750

 agcagttcct gccagtgcag atctggagag gagctggccc ggaaggcgtg 9800

 gttgtgaaag cgcccttctt atgttaggag gccttggcaa aattggattt 9850

 cttcaaaaat acatgtaaag gtctgttgtt gaattgtact ctgcccctgg 9900

 aagcagatac agatggctgc ctgctgctcg gctttgcttt tgcttttccc 9950

 accgtgtttt catctttgtt cacttgaggc tttccccagc tggtgtgtgc 10000

 aggacagttc atggtaatgt tgccctctga ggccccgtac accagaaggg 10050

 aggccctgga aaattttgtg cttccaacgt ggccttcaat tcttgctttt 10100

 ttgcccctcg gaagcatggg gcttttgagc acacttaaaa aaaaaaaccg 10150

 gaattc 10156

<210> 3655
<211> 2813
<212> PRT
<213> Homo sapien

<400> 3655
 Met Lys Leu Asn Pro Gln Gln Ala Pro Leu Tyr Gly Asp Cys Val
   1               5                  10                  15

 Val Thr Val Leu Leu Ala Glu Glu Asp Lys Ala Glu Asp Asp Val
                  20                  25                  30

 Val Phe Tyr Leu Val Phe Leu Gly Ser Thr Leu Arg His Cys Thr
                  35                  40                  45

 Ser Thr Arg Lys Val Ser Ser Asp Thr Leu Glu Thr Ile Ala Pro
                  50                  55                  60

 Gly His Asp Cys Cys Glu Thr Val Lys Val Gln Leu Cys Ala Ser
                  65                  70                  75

 Lys Glu Gly Leu Pro Val Phe Val Val Ala Glu Glu Asp Phe His
                  80                  85                  90

 Phe Val Gln Asp Glu Ala Tyr Asp Ala Ala Gln Phe Leu Ala Thr
                  95                 100                 105

 Ser Ala Gly Asn Gln Gln Ala Leu Asn Phe Thr Arg Phe Leu Asp
                 110                 115                 120

 Gln Ser Gly Pro Pro Ser Gly Asp Val Asn Ser Leu Asp Lys Lys
                 125                 130                 135

 Leu Val Leu Ala Phe Arg His Leu Lys Leu Pro Thr Glu Trp Asn
                 140                 145                 150

 Val Leu Gly Thr Asp Gln Ser Leu His Asp Ala Gly Pro Arg Glu
                 155                 160                 165

 Thr Leu Met His Phe Ala Val Arg Leu Gly Leu Leu Arg Leu Thr
                 170                 175                 180

 Trp Phe Leu Leu Gln Lys Pro Gly Gly Arg Gly Ala Leu Ser Ile
                 185                 190                 195

 His Asn Gln Glu Gly Ala Thr Pro Val Ser Leu Ala Leu Glu Arg
                 200                 205                 210

 Gly Tyr His Lys Leu His Gln Leu Leu Thr Glu Glu Asn Ala Gly
                 215                 220                 225

 Glu Pro Asp Ser Trp Ser Ser Leu Ser Tyr Glu Ile Pro Tyr Gly
                 230                 235                 240

 Asp Cys Ser Val Arg His His Arg Glu Leu Asp Ile Tyr Thr Leu
                 245                 250                 255

 Thr Ser Glu Ser Asp Ser His His Glu His Pro Phe Pro Gly Asp
                 260                 265                 270

 Gly Cys Thr Gly Pro Ile Phe Lys Leu Met Asn Ile Gln Gln Gln
                 275                 280                 285

 Leu Met Lys Thr Asn Leu Lys Gln Met Asp Ser Leu Met Pro Leu
                 290                 295                 300

 Met Met Thr Ala Gln Asp Pro Ser Ser Ala Pro Glu Thr Asp Gly
                 305                 310                 315

 Gln Phe Leu Pro Cys Ala Pro Glu Pro Thr Asp Pro Gln Arg Leu
                 320                 325                 330

 Ser Ser Ser Glu Glu Thr Glu Ser Thr Gln Cys Cys Pro Gly Ser
                 335                 340                 345

 Pro Val Ala Gln Thr Glu Ser Pro Cys Asp Leu Ser Ser Ile Val
                 350                 355                 360

 Glu Glu Glu Asn Thr Asp Arg Ser Cys Arg Lys Lys Asn Lys Gly
                 365                 370                 375

 Val Glu Arg Lys Gly Glu Glu Val Glu Pro Ala Pro Ile Val Asp
                 380                 385                 390

 Ser Gly Thr Val Ser Asp Gln Asp Ser Cys Leu Gln Ser Leu Pro
                 395                 400                 405

 Asp Cys Gly Val Lys Gly Thr Glu Gly Leu Ser Ser Cys Gly Asn
                 410                 415                 420

 Arg Asn Glu Glu Thr Gly Thr Lys Ser Ser Gly Met Pro Thr Asp
                 425                 430                 435

 Gln Glu Ser Leu Ser Ser Gly Asp Ala Val Leu Gln Arg Asp Leu
                 440                 445                 450

 Val Met Glu Pro Gly Thr Ala Gln Tyr Ser Ser Gly Gly Glu Leu
                 455                 460                 465

 Gly Gly Ile Ser Thr Thr Asn Val Ser Thr Pro Asp Thr Ala Gly
                 470                 475                 480

 Glu Met Glu His Gly Leu Met Asn Pro Asp Ala Thr Val Trp Lys
                 485                 490                 495

 Asn Val Leu Gln Gly Gly Glu Ser Thr Lys Glu Arg Phe Glu Asn
                 500                 505                 510

 Ser Asn Ile Gly Thr Ala Gly Ala Ser Asp Val His Val Thr Ser
                 515                 520                 525

 Lys Pro Val Asp Lys Ile Ser Val Pro Asn Cys Ala Pro Ala Ala
                 530                 535                 540

 Ser Ser Leu Asp Gly Asn Lys Pro Ala Glu Ser Ser Leu Ala Phe
                 545                 550                 555

 Ser Asn Glu Glu Thr Ser Thr Glu Lys Thr Ala Glu Thr Glu Thr
                 560                 565                 570

 Ser Arg Ser Arg Glu Glu Ser Ala Asp Ala Pro Val Asp Gln Asn
                 575                 580                 585

 Ser Val Val Ile Pro Ala Ala Ala Lys Asp Lys Ile Ser Asp Gly
                 590                 595                 600

 Leu Glu Pro Tyr Thr Leu Leu Ala Ala Gly Ile Gly Glu Ala Met
                 605                 610                 615

 Ser Pro Ser Asp Leu Ala Leu Leu Gly Leu Glu Glu Asp Val Met
                 620                 625                 630

 Pro His Gln Asn Ser Glu Thr Asn Ser Ser His Ala Gln Ser Gln
                 635                 640                 645

 Lys Gly Lys Ser Ser Pro Ile Cys Ser Thr Thr Gly Asp Asp Lys
                 650                 655                 660

 Leu Cys Ala Asp Ser Ala Cys Gln Gln Asn Thr Val Thr Ser Ser
                 665                 670                 675

 Gly Asp Leu Val Ala Lys Leu Cys Asp Asn Ile Val Ser Glu Ser
                 680                 685                 690

 Glu Ser Thr Thr Ala Arg Gln Pro Ser Ser Gln Asp Pro Pro Asp
                 695                 700                 705

 Ala Ser His Cys Glu Asp Pro Gln Ala His Thr Val Thr Ser Asp
                 710                 715                 720

 Pro Val Arg Asp Thr Gln Glu Arg Ala Asp Phe Cys Pro Phe Lys
                 725                 730                 735

 Val Val Asp Asn Lys Gly Gln Arg Lys Asp Val Lys Leu Asp Lys
                 740                 745                 750

 Pro Leu Thr Asn Met Leu Glu Val Val Ser His Pro His Pro Val
                 755                 760                 765

 Val Pro Lys Met Glu Lys Glu Leu Val Pro Asp Gln Ala Val Ile
                 770                 775                 780

 Ser Asp Ser Thr Phe Ser Leu Ala Asn Ser Pro Gly Ser Glu Ser
                 785                 790                 795

 Val Thr Lys Asp Asp Ala Leu Ser Phe Val Pro Ser Gln Lys Glu
                 800                 805                 810

 Lys Gly Thr Ala Thr Pro Glu Leu His Thr Ala Thr Asp Tyr Arg
                 815                 820                 825

 Asp Gly Pro Asp Gly Asn Ser Asn Glu Pro Asp Thr Arg Pro Leu
                 830                 835                 840

 Glu Asp Arg Ala Val Gly Leu Ser Thr Ser Ser Thr Ala Ala Glu
                 845                 850                 855

 Leu Gln His Gly Met Gly Asn Thr Ser Leu Thr Gly Leu Gly Gly
                 860                 865                 870

 Glu His Glu Gly Pro Ala Pro Pro Ala Ile Pro Glu Ala Leu Asn
                 875                 880                 885

 Ile Lys Gly Asn Thr Asp Ser Ser Leu Gln Ser Val Gly Lys Ala
                 890                 895                 900

 Thr Leu Ala Leu Asp Ser Val Leu Thr Glu Glu Gly Lys Leu Leu
                 905                 910                 915

 Val Val Ser Glu Ser Ser Ala Ala Gln Glu Gln Asp Lys Asp Lys
                 920                 925                 930

 Ala Val Thr Cys Ser Ser Ile Lys Glu Asn Ala Leu Ser Ser Gly
                 935                 940                 945

 Thr Leu Gln Glu Glu Gln Arg Thr Pro Pro Pro Gly Gln Asp Thr
                 950                 955                 960

 Gln Gln Phe His Glu Lys Ser Ile Ser Ala Asp Cys Ala Lys Asp
                 965                 970                 975

 Lys Ala Leu Gln Leu Ser Asn Ser Pro Gly Ala Ser Ser Ala Phe
                 980                 985                 990

 Leu Lys Ala Glu Thr Glu His Asn Lys Glu Val Ala Pro Gln Val
                 995                1000                1005

 Ser Leu Leu Thr Gln Gly Gly Ala Ala Gln Ser Leu Val Pro Pro
                1010                1015                1020

 Gly Ala Ser Leu Ala Thr Glu Ser Arg Gln Glu Ala Leu Gly Ala
                1025                1030                1035

 Glu His Asn Ser Ser Ala Leu Leu Pro Cys Leu Leu Pro Asp Gly
                1040                1045                1050

 Ser Asp Gly Ser Asp Ala Leu Asn Cys Ser Gln Pro Ser Pro Leu
                1055                1060                1065

 Asp Val Gly Val Lys Asn Thr Gln Ser Gln Gly Lys Thr Ser Ala
                1070                1075                1080

 Cys Glu Val Ser Gly Asp Val Thr Val Asp Val Thr Gly Val Asn
                1085                1090                1095

 Ala Leu Gln Gly Met Ala Glu Pro Arg Arg Glu Asn Ile Ser His
                1100                1105                1110

 Asn Thr Gln Asp Ile Leu Ile Pro Asn Val Leu Leu Ser Gln Glu
                1115                1120                1125

 Lys Asn Ala Val Leu Gly Leu Pro Val Ala Leu Gln Asp Lys Ala
                1130                1135                1140

 Val Thr Asp Pro Gln Gly Val Gly Thr Pro Glu Met Ile Pro Leu
                1145                1150                1155

 Asp Trp Glu Lys Gly Lys Leu Glu Gly Ala Asp His Ser Cys Thr
                1160                1165                1170

 Met Gly Asp Ala Glu Glu Ala Gln Ile Asp Asp Glu Ala His Pro
                1175                1180                1185

 Val Leu Leu Gln Pro Val Ala Lys Glu Leu Pro Thr Asp Met Glu
                1190                1195                1200

 Leu Ser Ala His Asp Asp Gly Ala Pro Ala Gly Val Arg Glu Val
                1205                1210                1215

 Met Arg Ala Pro Pro Ser Gly Arg Glu Arg Ser Thr Pro Ser Leu
                1220                1225                1230

 Pro Cys Met Val Ser Ala Gln Asp Ala Pro Leu Pro Lys Gly Ala
                1235                1240                1245

 Asp Leu Ile Glu Glu Ala Ala Ser Arg Ile Val Asp Ala Val Ile
                1250                1255                1260

 Glu Gln Val Lys Ala Ala Gly Ala Leu Leu Thr Glu Gly Glu Ala
                1265                1270                1275

 Cys His Met Ser Leu Ser Ser Pro Glu Leu Gly Pro Leu Thr Lys
                1280                1285                1290

 Gly Leu Glu Ser Ala Phe Thr Glu Lys Val Ser Thr Phe Pro Pro
                1295                1300                1305

 Gly Glu Ser Leu Pro Met Gly Ser Thr Pro Glu Glu Ala Thr Gly
                1310                1315                1320

 Ser Leu Ala Gly Cys Phe Ala Gly Arg Glu Glu Pro Glu Lys Ile
                1325                1330                1335

 Ile Leu Pro Val Gln Gly Pro Glu Pro Ala Ala Glu Met Pro Asp
                1340                1345                1350

 Val Lys Ala Glu Asp Glu Val Asp Phe Arg Ala Ser Ser Ile Ser
                1355                1360                1365

 Glu Glu Val Ala Val Gly Ser Ile Ala Ala Thr Leu Lys Met Lys
                1370                1375                1380

 Gln Gly Pro Met Thr Gln Ala Ile Asn Arg Glu Asn Trp Cys Thr
                1385                1390                1395

 Ile Glu Pro Cys Pro Asp Ala Ala Ser Leu Leu Ala Ser Lys Gln
                1400                1405                1410

 Ser Pro Glu Cys Glu Asn Phe Leu Asp Val Gly Leu Gly Arg Glu
                1415                1420                1425

 Cys Thr Ser Lys Gln Gly Val Leu Lys Arg Glu Ser Gly Ser Asp
                1430                1435                1440

 Ser Asp Leu Phe His Ser Pro Ser Asp Asp Met Asp Ser Ile Ile
                1445                1450                1455

 Phe Pro Lys Pro Glu Glu Glu His Leu Ala Cys Asp Ile Thr Gly
                1460                1465                1470

 Ser Ser Ser Ser Thr Asp Asp Thr Ala Ser Leu Asp Arg His Ser
                1475                1480                1485

 Ser His Gly Ser Asp Val Ser Leu Ser Gln Ile Leu Lys Pro Asn
                1490                1495                1500

 Arg Ser Arg Asp Arg Gln Ser Leu Asp Gly Phe Tyr Ser His Gly
                1505                1510                1515

 Met Gly Ala Glu Gly Arg Glu Ser Glu Ser Glu Pro Ala Asp Pro
                1520                1525                1530

 Gly Asp Val Glu Glu Glu Glu Met Asp Ser Ile Thr Glu Val Pro
                1535                1540                1545

 Ala Asn Cys Ser Val Leu Arg Ser Ser Met Arg Ser Leu Ser Pro
                1550                1555                1560

 Phe Arg Arg His Ser Trp Gly Pro Gly Lys Asn Ala Ala Ser Asp
                1565                1570                1575

 Ala Glu Met Asn His Arg Ser Ser Met Arg Val Leu Gly Asp Val
                1580                1585                1590

 Val Arg Arg Pro Pro Ile His Arg Arg Ser Phe Ser Leu Glu Gly
                1595                1600                1605

 Leu Thr Gly Gly Ala Gly Val Gly Asn Lys Pro Ser Ser Ser Leu
                1610                1615                1620

 Glu Val Ser Ser Ala Asn Ala Glu Glu Leu Arg His Pro Phe Ser
                1625                1630                1635

 Gly Glu Glu Arg Val Asp Ser Leu Val Ser Leu Ser Glu Glu Asp
                1640                1645                1650

 Leu Glu Ser Asp Gln Arg Glu His Arg Met Phe Asp Gln Gln Ile
                1655                1660                1665

 Cys His Arg Ser Lys Gln Gln Gly Phe Asn Tyr Cys Thr Ser Ala
                1670                1675                1680

 Ile Ser Ser Pro Leu Thr Lys Ser Ile Ser Leu Met Thr Ile Ser
                1685                1690                1695

 His Pro Gly Leu Asp Asn Ser Arg Pro Phe His Ser Thr Phe His
                1700                1705                1710

 Asn Thr Ser Ala Asn Leu Thr Glu Ser Ile Thr Glu Glu Asn Tyr
                1715                1720                1725

 Asn Phe Leu Pro His Ser Pro Ser Lys Lys Asp Ser Glu Trp Lys
                1730                1735                1740

 Ser Gly Thr Lys Val Ser Arg Thr Phe Ser Tyr Ile Lys Asn Lys
                1745                1750                1755

 Met Ser Ser Ser Lys Lys Ser Lys Glu Lys Glu Lys Glu Lys Asp
                1760                1765                1770

 Lys Ile Lys Glu Lys Glu Lys Asp Ser Lys Asp Lys Glu Lys Asp
                1775                1780                1785

 Lys Lys Thr Val Asn Gly His Thr Phe Ser Ser Ile Pro Val Val
                1790                1795                1800

 Gly Pro Ile Ser Cys Ser Gln Cys Met Lys Pro Phe Thr Asn Lys
                1805                1810                1815

 Asp Ala Tyr Thr Cys Ala Asn Cys Ser Ala Phe Val His Lys Gly
                1820                1825                1830

 Cys Arg Glu Ser Leu Ala Ser Cys Ala Lys Val Lys Met Lys Gln
                1835                1840                1845

 Pro Lys Gly Ser Leu Gln Ala His Asp Thr Ser Ser Leu Pro Thr
                1850                1855                1860

 Val Ile Met Arg Asn Lys Pro Ser Gln Pro Lys Glu Arg Pro Arg
                1865                1870                1875

 Ser Ala Val Leu Leu Val Asp Glu Thr Ala Thr Thr Pro Ile Phe
                1880                1885                1890

 Ala Asn Arg Arg Ser Gln Gln Ser Val Ser Leu Ser Lys Ser Val
                1895                1900                1905

 Ser Ile Gln Asn Ile Thr Gly Val Gly Asn Asp Glu Asn Met Ser
                1910                1915                1920

 Asn Thr Trp Lys Phe Leu Ser His Ser Thr Asp Ser Leu Asn Lys
                1925                1930                1935

 Ile Ser Lys Val Asn Glu Ser Thr Glu Ser Leu Thr Asp Glu Gly
                1940                1945                1950

 Val Gly Thr Asp Met Asn Glu Gly Gln Leu Leu Gly Asp Phe Glu
                1955                1960                1965

 Ile Glu Ser Lys Gln Leu Glu Ala Glu Ser Trp Ser Arg Ile Ile
                1970                1975                1980

 Asp Ser Lys Phe Leu Lys Gln Gln Lys Lys Asp Val Val Lys Arg
                1985                1990                1995

 Gln Glu Val Ile Tyr Glu Leu Met Gln Thr Glu Phe His His Val
                2000                2005                2010

 Arg Thr Leu Lys Ile Met Ser Gly Val Tyr Ser Gln Gly Met Met
                2015                2020                2025

 Ala Asp Leu Leu Phe Glu Gln Gln Met Val Glu Lys Leu Phe Pro
                2030                2035                2040

 Cys Leu Asp Glu Leu Ile Ser Ile His Ser Gln Phe Phe Gln Arg
                2045                2050                2055

 Ile Leu Glu Arg Lys Lys Glu Ser Leu Val Asp Lys Ser Glu Lys
                2060                2065                2070

 Asn Phe Leu Ile Lys Arg Ile Gly Asp Val Leu Val Asn Gln Phe
                2075                2080                2085

 Ser Gly Glu Asn Ala Glu Arg Leu Lys Lys Thr Tyr Gly Lys Phe
                2090                2095                2100

 Cys Gly Gln His Asn Gln Ser Val Asn Tyr Phe Lys Asp Leu Tyr
                2105                2110                2115

 Ala Lys Asp Lys Arg Phe Gln Ala Phe Val Lys Lys Lys Met Ser
                2120                2125                2130

 Ser Ser Val Val Arg Arg Leu Gly Ile Pro Glu Cys Ile Leu Leu
                2135                2140                2145

 Val Thr Gln Arg Ile Thr Lys Tyr Pro Val Leu Phe Gln Arg Ile
                2150                2155                2160

 Leu Gln Cys Thr Lys Asp Asn Glu Val Glu Gln Glu Asp Leu Ala
                2165                2170                2175

 Gln Ser Leu Ser Leu Val Lys Asp Val Ile Gly Ala Val Asp Ser
                2180                2185                2190

 Lys Val Ala Ser Tyr Glu Lys Lys Val Arg Leu Asn Glu Ile Tyr
                2195                2200                2205

 Thr Lys Thr Asp Ser Lys Ser Ile Met Arg Met Lys Ser Gly Gln
                2210                2215                2220

 Met Phe Ala Lys Glu Asp Leu Lys Arg Lys Lys Leu Val Arg Asp
                2225                2230                2235

 Gly Ser Val Phe Leu Lys Asn Ala Ala Gly Arg Leu Lys Glu Val
                2240                2245                2250

 Gln Ala Val Leu Leu Thr Asp Ile Leu Val Phe Leu Gln Glu Lys
                2255                2260                2265

 Asp Gln Lys Tyr Ile Phe Ala Ser Leu Asp Gln Lys Ser Thr Val
                2270                2275                2280

 Ile Ser Leu Lys Lys Leu Ile Val Arg Glu Val Ala His Glu Glu
                2285                2290                2295

 Lys Gly Leu Phe Leu Ile Ser Met Gly Met Thr Asp Pro Glu Met
                2300                2305                2310

 Val Glu Val His Ala Ser Ser Lys Glu Glu Arg Asn Ser Trp Ile
                2315                2320                2325

 Gln Ile Ile Gln Asp Thr Ile Asn Thr Leu Asn Arg Asp Glu Asp
                2330                2335                2340

 Glu Gly Ile Pro Ser Glu Asn Glu Glu Glu Lys Lys Met Leu Asp
                2345                2350                2355

 Thr Arg Ala Arg Glu Leu Lys Glu Gln Leu His Gln Lys Asp Gln
                2360                2365                2370

 Lys Ile Leu Leu Leu Leu Glu Glu Lys Glu Met Ile Phe Arg Asp
                2375                2380                2385

 Met Ala Glu Cys Ser Thr Pro Leu Pro Glu Asp Cys Ser Pro Thr
                2390                2395                2400

 His Ser Pro Arg Val Leu Phe Arg Ser Asn Thr Glu Glu Ala Leu
                2405                2410                2415

 Lys Gly Gly Pro Leu Met Lys Ser Ala Ile Asn Glu Val Glu Ile
                2420                2425                2430

 Leu Gln Gly Leu Val Ser Gly Asn Leu Gly Gly Thr Leu Gly Pro
                2435                2440                2445

 Thr Val Ser Ser Pro Ile Glu Gln Asp Val Val Gly Pro Val Ser
                2450                2455                2460

 Leu Pro Arg Arg Ala Glu Thr Phe Gly Gly Phe Asp Ser His Gln
                2465                2470                2475

 Met Asn Ala Ser Lys Gly Gly Glu Lys Glu Glu Gly Asp Asp Gly
                2480                2485                2490

 Gln Asp Leu Arg Arg Thr Glu Ser Asp Ser Gly Leu Lys Lys Gly
                2495                2500                2505

 Gly Asn Ala Asn Leu Val Phe Met Leu Lys Arg Asn Ser Glu Gln
                2510                2515                2520

 Val Val Gln Ser Val Val His Leu Tyr Glu Leu Leu Ser Ala Leu
                2525                2530                2535

 Gln Gly Val Val Leu Gln Gln Asp Ser Tyr Ile Glu Asp Gln Lys
                2540                2545                2550

 Leu Val Leu Ser Glu Arg Ala Leu Thr Arg Ser Leu Ser Arg Pro
                2555                2560                2565

 Ser Ser Leu Ile Glu Gln Glu Lys Gln Arg Ser Leu Glu Lys Gln
                2570                2575                2580

 Arg Gln Asp Leu Ala Asn Leu Gln Lys Gln Gln Ala Gln Tyr Leu
                2585                2590                2595

 Glu Glu Lys Arg Arg Arg Glu Arg Glu Trp Glu Ala Arg Glu Arg
                2600                2605                2610

 Glu Leu Arg Glu Arg Glu Ala Leu Leu Ala Gln Arg Glu Glu Glu
                2615                2620                2625

 Val Gln Gln Gly Gln Gln Asp Leu Glu Lys Glu Arg Glu Glu Leu
                2630                2635                2640

 Gln Gln Lys Lys Gly Thr Tyr Gln Tyr Asp Leu Glu Arg Leu Arg
                2645                2650                2655

 Ala Ala Gln Lys Gln Leu Glu Arg Glu Gln Glu Gln Leu Arg Arg
                2660                2665                2670

 Glu Ala Glu Arg Leu Ser Gln Arg Gln Thr Glu Arg Asp Leu Cys
                2675                2680                2685

 Gln Val Ser His Pro His Thr Lys Leu Met Arg Ile Pro Ser Phe
                2690                2695                2700

 Phe Pro Ser Pro Glu Glu Pro Pro Ser Pro Ser Ala Pro Ser Ile
                2705                2710                2715

 Ala Lys Ser Gly Ser Leu Asp Ser Glu Leu Ser Val Ser Pro Lys
                2720                2725                2730

 Arg Asn Ser Ile Ser Arg Thr His Lys Asp Lys Gly Pro Phe His
                2735                2740                2745

 Ile Leu Ser Ser Thr Ser Gln Thr Asn Lys Gly Pro Glu Gly Gln
                2750                2755                2760

 Ser Gln Ala Pro Ala Ser Thr Ser Ala Ser Thr Arg Leu Phe Gly
                2765                2770                2775

 Leu Thr Lys Pro Lys Glu Lys Lys Glu Lys Lys Lys Lys Asn Lys
                2780                2785                2790

 Thr Ser Arg Ser Gln Pro Gly Asp Gly Pro Ala Ser Glu Val Ser
                2795                2800                2805

 Ala Glu Gly Glu Glu Ile Phe Cys
                2810

<210> 3656
<211> 4224
<212> DNA
<213> Homo sapien

<400> 3656
 caaggggcat tccaactggt ggaggagatc cggaaccacg tgctgagaga 50

 cagctctggg atcaggagct tggaggagtt gtgtctgcaa gtgaccgacc 100

 tgctgccagg ccttaggaag ctcaggaacc tactccctga gcatggatgc 150

 ctgctgctgt cccctgggaa cttctggcag aatgactggg aacgcttcca 200

 tgctgatcct gacatcattg ggaccatcca ccagcacgag cctaaaaccc 250

 tgcagacttc agccacactc aaagacttgt tatttggtgt tcctgggaag 300

 tacagcgggg tgagcctcta caccaggaag aggatggtct cctacaccat 350

 caccctggtc ttccagcact accatgccaa gttcctgggc agcctgcgtg 400

 cccgcctgat gcttctgcac cccagcccca actgcagcct tcgggcggag 450

 agcctggtcc acgtgcactt caaggaggag attggtgtcg ctcgaacgac 500

 caagagggtg ttcgactgct agagccgagc gaagcgatgc ctaaatcaaa 550

 ggaacttgtt tcttcaagct cttctggcag tgattctgac agtgaggttg 600

 acaaaaagtt aaagaggaaa aagcaagttg ctccagaaaa acctgtaaag 650

 aaacaaaaga caggtgagac ttcgagagcc ctgtcatctt ctaaacagag 700

 cagcagcagc agagatgata acatgtttca gattgggaaa atgaggtacg 750

 ttagtgttcg cgattttaaa ggcaaagtgc taattgatat tagagaatat 800

 tggatggatc ctgaaggtga aatgaaacca ggaagaaaag gtatttcttt 850

 aaatccagaa caatggagcc agctgaagga acagatttct gacattgatg 900

 atgcagtaag aaaactgtaa aattcgagcc atataaataa aacctgtact 950

 gttctagttg ttttaatctg tctttttaca ttggcttttg ttttctaaat 1000

 gttctccaag ctattgtatg tttggattgc agaagaattt gtaagatgaa 1050

 tacttttttt taatgtgcat tattaaaaat attgagtgaa gctaattgtc 1100

 aactttatta aggattactt tgtctgccca ccacctagtg taaaataaaa 1150

 tcaagtaata caatcttaac tgttgtggcc ttttttgatc ataagagttg 1200

 gtactgttta aggccaaaag taacagtttt tatagatctt ttagtttcaa 1250

 ctcagctttt acaataaaaa ggatttgtat tgcattgagt ttataaactt 1300

 ttggtttgtg aacttcatat ttgatctttt ctcttccaat caaatgtcta 1350

 ggcttgtttg acttccaccc ccaatggttt ttcactcttt ttatttactt 1400

 cattttcctt taataactta atctcttcat gttcagtttt tacttcactc 1450

 tttattcttt tctttgatta tggtatgctt atttggaaag tcagtgaaac 1500

 tgtcaaaatg ttatctcaat aagatactta tatgagaact acaatcaccg 1550

 aatctactgt attcaatatt agcagatcta atttgataaa caacatggct 1600

 tgtgtgaaaa ctgagcaggt gtttgtttac ccatagtgtt ctgtgtagtt 1650

 attgcttagt ctgcagaaaa taatgactta gatgagatgt ctgacttgct 1700

 ttcacttatt aaacatgttc accatgggat gatgtctgta acatcagata 1750

 ttgttcaact agactaggat ttaataaaaa ttgtgaaagc ttactggcct 1800

 aacattttat tttataatat tgggtatgaa ttatatgtag ccagagatgt 1850

 cattaagctt tactgttata gtaggtaata tggttagttt gtagggaaaa 1900

 gagcatatga gcacatgctt gtgtattttg gcctttgccc cagtagaaca 1950

 gaccaatggc attctagact tgatgatact aagttttagc agacactagt 2000

 aagtggtttg tatttaacca tactgatgaa gcagacagat tgaggcacag 2050

 attttagtgg ctttgtggca ataaataggg catggtgtgc cttaggaaaa 2100

 gaatgtttat aaagggaatt ataactgaaa ttaaaggagg cggcagtgaa 2150

 gaggaaataa ttctcttcta tctaaatgat atacatatga tattttgaga 2200

 tttttataac agcagtggaa cacaattcta ggtagagtag aaaaaggaaa 2250

 gttttaaaga catataaaag attcttgttg acaaattatt tttggtagca 2300

 aatctcaaat ggttacctgc tattaaggtc tgccatatta gagttttgca 2350

 ctattttgct accaagtttg attcatacat ctaaaacatt ttgtagttac 2400

 ttgtcaagga cttaatttga aaatcatttg ccaggccaca tagttatcaa 2450

 tttttttttc tatcagctat tctgttgtat ttctaaaaca ttttttagat 2500

 gactttttaa agtatattta gcagtaacct tatgaggttc aaattggtaa 2550

 atctcttgta atttagcctt catcgaataa taggtaccag tgtattaaaa 2600

 atgtgtattt tttgcagccc cttgaaccag agtaggttca gagaaactcc 2650

 caaagtttgt actttagaca catcaagctt gattggtaac ttccctcctt 2700

 ttttggggaa catgtttgtg tcctattaac ttaattggat agatttttaa 2750

 atatttctta tttttggcac acggaaaggg tagttcgagt acagaacttt 2800

 gatttttggt gtagatgcag agggaatgat gggtaaattt cctaggttta 2850

 tgtgaattta gggggtgtat gcattttgaa acaatctact aacagatggt 2900

 gctgaaatct attacctaca tgttttctag ttgttcagca ttatgttaat 2950

 gaagcctcca tataaggagt gtttctctgg cacagttggt aagttgactg 3000

 ctaacttcat ttaaatgtgt tactggatat gcagtatact gaaattatta 3050

 atcagtttgt gtataggaaa agagaactgg gttaaaagca aattaacttg 3100

 ttctgaaaag aaagtataga ttaattttgt tttctgttta aattttatct 3150

 ccttggtaaa gatttttttt tcctgggcag aaaacttggc atttttaggc 3200

 gtagatacct taccttacaa tgccaaaatg aatttaattc cagtactcag 3250

 gtttttccct ttaacagact ctatgtgtat cagggctttc taatgggttt 3300

 ttcctcttcg tttttaaaat gtgagtagca tttgaccaat ttccagtgct 3350

 cttagcattt tacttaaaga acaaccacta caaaagaaaa tctttgtaat 3400

 ttgattgtct tttgctttgc ttcattaatg cctaagaact taagaatact 3450

 cctacctcat tagctactca agatgctgtg acgatcaaat ctattctaca 3500

 taatgcgttt agaaacaaag acttgggtga aaaatgaaat aagtatattc 3550

 tgacttggct attgagggga aaattcagta ttaagtgttc ctcacaggag 3600

 atatgttagc agaatactat aaaagtttga aatttttaaa aagtaaaagt 3650

 acttaaattt aggtatctct cctgaaattc tttgcagttc attttttatg 3700

 gcagttaatc cagtgaaaca ctcaaaagtt tttttttttt taaaagtgtt 3750

 tttccagata aactgtaggg tgaacattca cataatcaca aatatgtaat 3800

 tctgtaattg tggaatgctt gtatgctttg ttttcgtaca tcttccatgg 3850

 agatgtctga atataatact ccatctgtga atattttaaa tgtggcattt 3900

 attgtggatg cattttcaca atatatgtta atgggagcga tccattatca 3950

 gtgaaaagta tcaagtgttt ataaaatttt taggaatggc agattcacag 4000

 aacatgctag tcagctggca gtttaacctc gtaaagataa cagagaatta 4050

 tagtcaaacc agtaaacaag gaatttactt ttcaaaagtt ttgaattagg 4100

 cctatggtaa ggtaacattg ctttgttgta cttttgaaca agagctcctc 4150

 ctgatcacta ttacatattt ttctagaaaa tctaaagttc agaagagaat 4200

 gtatcactgc tgacttttat tcca 4224

<210> 3657
<211> 173
<212> PRT
<213> Homo sapien

<400> 3657
 Gln Gly Ala Phe Gln Leu Val Glu Glu Ile Arg Asn His Val Leu
   1               5                  10                  15

 Arg Asp Ser Ser Gly Ile Arg Ser Leu Glu Glu Leu Cys Leu Gln
                  20                  25                  30

 Val Thr Asp Leu Leu Pro Gly Leu Arg Lys Leu Arg Asn Leu Leu
                  35                  40                  45

 Pro Glu His Gly Cys Leu Leu Leu Ser Pro Gly Asn Phe Trp Gln
                  50                  55                  60

 Asn Asp Trp Glu Arg Phe His Ala Asp Pro Asp Ile Ile Gly Thr
                  65                  70                  75

 Ile His Gln His Glu Pro Lys Thr Leu Gln Thr Ser Ala Thr Leu
                  80                  85                  90

 Lys Asp Leu Leu Phe Gly Val Pro Gly Lys Tyr Ser Gly Val Ser
                  95                 100                 105

 Leu Tyr Thr Arg Lys Arg Met Val Ser Tyr Thr Ile Thr Leu Val
                 110                 115                 120

 Phe Gln His Tyr His Ala Lys Phe Leu Gly Ser Leu Arg Ala Arg
                 125                 130                 135

 Leu Met Leu Leu His Pro Ser Pro Asn Cys Ser Leu Arg Ala Glu
                 140                 145                 150

 Ser Leu Val His Val His Phe Lys Glu Glu Ile Gly Val Ala Arg
                 155                 160                 165

 Thr Thr Lys Arg Val Phe Asp Cys
                 170

<210> 3658
<211> 2427
<212> DNA
<213> Homo sapien

<400> 3658
 cggacgcgtg gggagaggct gtttaccaga acagcataac aagggcaggt 50

 ctgactgcaa ggctgggact gggaggcaga gccgccgcca agggggcctc 100

 ggttaaacac tggtcgttca atcacctgca agacgaagga ggcaaggatg 150

 ctgttggcct gggtacaagc attcctcgtc agcaacatgc tcctagcaga 200

 agcctatgga tctggaggct gtttctggga caacggccac ctgtaccggg 250

 aggaccagac ctcccccgcg ccgggcctcc gctgcctcaa ctggctggac 300

 gcgcagagcg ggctggcctc ggcccccgtg tcgggggccg gcaatcacag 350

 ttactgccga aacccggacg aggacccgcg cgggccctgg tgctacgtca 400

 gtggcgaggc cggcgtccct gagaaacggc cttgcgagga cctgcgctgt 450

 ccagagacca cctcccaggc cctgccagcc ttcacgacag aaatccagga 500

 agcgtctgaa gggccaggtg cagatgaggt gcaggtgttc gctcctgcca 550

 acgccctgcc cgctcggagt gaggcggcag ctgtgcagcc agtgattggg 600

 atcagccagc gggtgcggat gaactccaag gagaaaaagg acctgggaac 650

 tctgggctac gtgctgggca ttaccatgat ggtgatcatc attgccatcg 700

 gagctggcat catcttgggc tactcctaca agagggggaa ggatttgaaa 750

 gaacagcatg atcagaaagt atgtgagagg gagatgcagc gaatcactct 800

 gcccttgtct gccttcacca accccacctg tgagattgtg gatgagaaga 850

 ctgtcgtggt ccacaccagc cagactccag ttgaccctca ggagggcagc 900

 acccccctta tgggccaggc cgggactcct ggggcctgag cccccccagt 950

 gggcaggagc ccatgcagac actggtgcag gacagcccac cctcctacag 1000

 ctaggaggaa ctaccacttt gtgttctggt taaaacccta ccactccccc 1050

 gcttttttgg cgaatcctag taagagtgac agaagcaggt ggccctgtgg 1100

 gctgagggta aggctgggta gggtcctaac agtgctcctt gtccatccct 1150

 tggagcagat tttgtctgtg gatggagaca gtggcagctc ccacagtgat 1200

 gctgctgcta agggcttcca aacattgcct gcacccctgg aactgaacca 1250

 gggatagacg gggagctccc ccaggctcct ctgtgcttta ctaagatggc 1300

 ctcagtctcc actgtgggct tgagtggcat acactgttat tcatggttaa 1350

 ggtaaagcag gtcaagggat ggcattgaaa aaatatattt agtttttaaa 1400

 atatttggga tggaactccc tactgacctc tgagaactgg aaacgagttt 1450

 gtacagaagt cagaactttg ggttgggaat gagatctagg ttgtggctgc 1500

 tggtatgctt cagcttgctg gcaatgatgt gccttgacaa ccgtgggcca 1550

 ggcctgggcc cagggactct tcctgtttca taaggaaagg aagaattgca 1600

 ctgagcattc cacttaggaa gaggatagag aaggatctgc tccgcctttg 1650

 gccacaggag cagaggcaga cctgggatgc cccagtttct cttcagggat 1700

 ggatagtgac ctgtcttcat tttgcacagg taagagagta gttagctaac 1750

 ctatgggaat tatactgtgg ggccttgtga gctgcttcta agaggctaac 1800

 ctggaaacta agctcagagg caaggtaata aagcacttca gggcttgctc 1850

 cccaagtggg cctgatttag caggtggtcc tgcgggcgtc caggtcagca 1900

 ccttcctgta gggcactggg gctagggtca cagcccctaa ctcataaagc 1950

 aatcaaagaa ccattagaaa gggctcatta agccttttgg acacaggacc 2000

 ccagagagga aaaagtgact tgcccaaggt cgtaagcaag ctactggcat 2050

 ggcaagagcc cagcttcctg acggagcgca acatttctcc actgcactgt 2100

 gctagcagct cagcagggcc tctaacctgt gatgtcacac tcaagaggcc 2150

 ttggcagctc ctagccatag agcttccttt ccagaaccct tccactgccc 2200

 aatgtggaga caggggttag tggggctttc tatggagcca tctgctttgg 2250

 ggacctagac ctcaggtggt ctcttggtgt tagtgatgct ggagaagaga 2300

 atattactgg tttctacttt tctataaagg catttctcta tatacatgtt 2350

 ttatatacct cattctgaca cctgcatata gtgtgggaaa ttgctctgca 2400

 tttgacttaa ttaaaaaaaa aaaaaaa 2427

<210> 3659
<211> 263
<212> PRT
<213> Homo sapien

<400> 3659
 Met Leu Leu Ala Trp Val Gln Ala Phe Leu Val Ser Asn Met Leu
   1               5                  10                  15

 Leu Ala Glu Ala Tyr Gly Ser Gly Gly Cys Phe Trp Asp Asn Gly
                  20                  25                  30

 His Leu Tyr Arg Glu Asp Gln Thr Ser Pro Ala Pro Gly Leu Arg
                  35                  40                  45

 Cys Leu Asn Trp Leu Asp Ala Gln Ser Gly Leu Ala Ser Ala Pro
                  50                  55                  60

 Val Ser Gly Ala Gly Asn His Ser Tyr Cys Arg Asn Pro Asp Glu
                  65                  70                  75

 Asp Pro Arg Gly Pro Trp Cys Tyr Val Ser Gly Glu Ala Gly Val
                  80                  85                  90

 Pro Glu Lys Arg Pro Cys Glu Asp Leu Arg Cys Pro Glu Thr Thr
                  95                 100                 105

 Ser Gln Ala Leu Pro Ala Phe Thr Thr Glu Ile Gln Glu Ala Ser
                 110                 115                 120

 Glu Gly Pro Gly Ala Asp Glu Val Gln Val Phe Ala Pro Ala Asn
                 125                 130                 135

 Ala Leu Pro Ala Arg Ser Glu Ala Ala Ala Val Gln Pro Val Ile
                 140                 145                 150

 Gly Ile Ser Gln Arg Val Arg Met Asn Ser Lys Glu Lys Lys Asp
                 155                 160                 165

 Leu Gly Thr Leu Gly Tyr Val Leu Gly Ile Thr Met Met Val Ile
                 170                 175                 180

 Ile Ile Ala Ile Gly Ala Gly Ile Ile Leu Gly Tyr Ser Tyr Lys
                 185                 190                 195

 Arg Gly Lys Asp Leu Lys Glu Gln His Asp Gln Lys Val Cys Glu
                 200                 205                 210

 Arg Glu Met Gln Arg Ile Thr Leu Pro Leu Ser Ala Phe Thr Asn
                 215                 220                 225

 Pro Thr Cys Glu Ile Val Asp Glu Lys Thr Val Val Val His Thr
                 230                 235                 240

 Ser Gln Thr Pro Val Asp Pro Gln Glu Gly Ser Thr Pro Leu Met
                 245                 250                 255

 Gly Gln Ala Gly Thr Pro Gly Ala
                 260

<210> 3660
<211> 2427
<212> DNA
<213> Homo sapien

<400> 3660
 cggacgcgtg gggagaggct gtttaccaga acagcataac aagggcaggt 50

 ctgactgcaa ggctgggact gggaggcaga gccgccgcca agggggcctc 100

 ggttaaacac tggtcgttca atcacctgca agacgaagga ggcaaggatg 150

 ctgttggcct gggtacaagc attcctcgtc agcaacatgc tcctagcaga 200

 agcctatgga tctggaggct gtttctggga caacggccac ctgtaccggg 250

 aggaccagac ctcccccgcg ccgggcctcc gctgcctcaa ctggctggac 300

 gcgcagagcg ggctggcctc ggcccccgtg tcgggggccg gcaatcacag 350

 ttactgccga aacccggacg aggacccgcg cgggccctgg tgctacgtca 400

 gtggcgaggc cggcgtccct gagaaacggc cttgcgagga cctgcgctgt 450

 ccagagacca cctcccaggc cctgccagcc ttcacgacag aaatccagga 500

 agcgtctgaa gggccaggtg cagatgaggt gcaggtgttc gctcctgcca 550

 acgccctgcc cgctcggagt gaggcggcag ctgtgcagcc agtgattggg 600

 atcagccagc gggtgcggat gaactccaag gagaaaaagg acctgggaac 650

 tctgggctac gtgctgggca ttaccatgat ggtgatcatc attgccatcg 700

 gagctggcat catcttgggc tactcctaca agagggggaa ggatttgaaa 750

 gaacagcatg atcagaaagt atgtgagagg gagatgcagc gaatcactct 800

 gcccttgtct gccttcacca accccacctg tgagattgtg gatgagaaga 850

 ctgtcgtggt ccacaccagc cagactccag ttgaccctca ggagggcagc 900

 acccccctta tgggccaggc cgggactcct ggggcctgag cccccccagt 950

 gggcaggagc ccatgcagac actggtgcag gacagcccac cctcctacag 1000

 ctaggaggaa ctaccacttt gtgttctggt taaaacccta ccactccccc 1050

 gcttttttgg cgaatcctag taagagtgac agaagcaggt ggccctgtgg 1100

 gctgagggta aggctgggta gggtcctaac agtgctcctt gtccatccct 1150

 tggagcagat tttgtctgtg gatggagaca gtggcagctc ccacagtgat 1200

 gctgctgcta agggcttcca aacattgcct gcacccctgg aactgaacca 1250

 gggatagacg gggagctccc ccaggctcct ctgtgcttta ctaagatggc 1300

 ctcagtctcc actgtgggct tgagtggcat acactgttat tcatggttaa 1350

 ggtaaagcag gtcaagggat ggcattgaaa aaatatattt agtttttaaa 1400

 atatttggga tggaactccc tactgacctc tgagaactgg aaacgagttt 1450

 gtacagaagt cagaactttg ggttgggaat gagatctagg ttgtggctgc 1500

 tggtatgctt cagcttgctg gcaatgatgt gccttgacaa ccgtgggcca 1550

 ggcctgggcc cagggactct tcctgtttca taaggaaagg aagaattgca 1600

 ctgagcattc cacttaggaa gaggatagag aaggatctgc tccgcctttg 1650

 gccacaggag cagaggcaga cctgggatgc cccagtttct cttcagggat 1700

 ggatagtgac ctgtcttcat tttgcacagg taagagagta gttagctaac 1750

 ctatgggaat tatactgtgg ggccttgtga gctgcttcta agaggctaac 1800

 ctggaaacta agctcagagg caaggtaata aagcacttca gggcttgctc 1850

 cccaagtggg cctgatttag caggtggtcc tgcgggcgtc caggtcagca 1900

 ccttcctgta gggcactggg gctagggtca cagcccctaa ctcataaagc 1950

 aatcaaagaa ccattagaaa gggctcatta agccttttgg acacaggacc 2000

 ccagagagga aaaagtgact tgcccaaggt cgtaagcaag ctactggcat 2050

 ggcaagagcc cagcttcctg acggagcgca acatttctcc actgcactgt 2100

 gctagcagct cagcagggcc tctaacctgt gatgtcacac tcaagaggcc 2150

 ttggcagctc ctagccatag agcttccttt ccagaaccct tccactgccc 2200

 aatgtggaga caggggttag tggggctttc tatggagcca tctgctttgg 2250

 ggacctagac ctcaggtggt ctcttggtgt tagtgatgct ggagaagaga 2300

 atattactgg tttctacttt tctataaagg catttctcta tatacatgtt 2350

 ttatatacct cattctgaca cctgcatata gtgtgggaaa ttgctctgca 2400

 tttgacttaa ttaaaaaaaa aaaaaaa 2427

<210> 3661
<211> 263
<212> PRT
<213> Homo sapien

<400> 3661
 Met Leu Leu Ala Trp Val Gln Ala Phe Leu Val Ser Asn Met Leu
   1               5                  10                  15

 Leu Ala Glu Ala Tyr Gly Ser Gly Gly Cys Phe Trp Asp Asn Gly
                  20                  25                  30

 His Leu Tyr Arg Glu Asp Gln Thr Ser Pro Ala Pro Gly Leu Arg
                  35                  40                  45

 Cys Leu Asn Trp Leu Asp Ala Gln Ser Gly Leu Ala Ser Ala Pro
                  50                  55                  60

 Val Ser Gly Ala Gly Asn His Ser Tyr Cys Arg Asn Pro Asp Glu
                  65                  70                  75

 Asp Pro Arg Gly Pro Trp Cys Tyr Val Ser Gly Glu Ala Gly Val
                  80                  85                  90

 Pro Glu Lys Arg Pro Cys Glu Asp Leu Arg Cys Pro Glu Thr Thr
                  95                 100                 105

 Ser Gln Ala Leu Pro Ala Phe Thr Thr Glu Ile Gln Glu Ala Ser
                 110                 115                 120

 Glu Gly Pro Gly Ala Asp Glu Val Gln Val Phe Ala Pro Ala Asn
                 125                 130                 135

 Ala Leu Pro Ala Arg Ser Glu Ala Ala Ala Val Gln Pro Val Ile
                 140                 145                 150

 Gly Ile Ser Gln Arg Val Arg Met Asn Ser Lys Glu Lys Lys Asp
                 155                 160                 165

 Leu Gly Thr Leu Gly Tyr Val Leu Gly Ile Thr Met Met Val Ile
                 170                 175                 180

 Ile Ile Ala Ile Gly Ala Gly Ile Ile Leu Gly Tyr Ser Tyr Lys
                 185                 190                 195

 Arg Gly Lys Asp Leu Lys Glu Gln His Asp Gln Lys Val Cys Glu
                 200                 205                 210

 Arg Glu Met Gln Arg Ile Thr Leu Pro Leu Ser Ala Phe Thr Asn
                 215                 220                 225

 Pro Thr Cys Glu Ile Val Asp Glu Lys Thr Val Val Val His Thr
                 230                 235                 240

 Ser Gln Thr Pro Val Asp Pro Gln Glu Gly Ser Thr Pro Leu Met
                 245                 250                 255

 Gly Gln Ala Gly Thr Pro Gly Ala
                 260

<210> 3662
<211> 7480
<212> DNA
<213> Homo sapien

<400> 3662
 ctccacagta cctgaatgga gagcgaaaga taatgatcta cgattactgc 50

 tgacaaatgg aagaataatt aaagatgaaa ggcagccctt tgcagatcaa 100

 agtctttata cagcagatag tgaaaatgaa gaggataaaa gaaggacaaa 150

 aaaggcaaaa atgaagatag aagagagttc aggagtagag ggagtggaac 200

 atgaagaatc tcaaaaacca ctgaatgggt tttttacaag tgtgaaatca 250

 gaactcagga gtagatcatc aggatattct gatatttctg agtcagaaga 300

 ctccggaccc gagtgcactg cactgaaaag tatctttacc actgaagagt 350

 ctgaaagttc aggtgatgaa aagaaacaag aaataacatc caactttaag 400

 gaggaatcta atgtgatgag gaacttcctt caaaagagcc agaagccatc 450

 tagaagtgaa attccaatta aaagggaatg tcctacctcg acgagcacag 500

 aggaagaagc tattcagggc atgctgtcta tggcagggtt gcactattcc 550

 acgtgtttac aaaggcaaat acaaagcaca gactgcagtg gtgaaagaaa 600

 ctctctccag gatcccagca gctgccatgg cagtaaccat gaggttaggc 650

 agttgtatcg ctatgataaa ccagtggaat gtggatacca tgtcaagact 700

 gaagatccag acttgaggac ttcctcctgg attaaacagt ttgatacttc 750

 cagatttcat cctcaggatc taagtagaag ccagaaatgc atcagaaagg 800

 aaggttcatc agaaattagt cagagggtac aaagtaggaa ttatgtggac 850

 agcagcggct caagccttca gaatggaaag tatatgcaga attcaaacct 900

 gacttcgggg gcgtgccaga taagtaatgg cagtctaagc ccagaaaggc 950

 cagttggtga aacttccttc tcggtgcccc ttcaccccac caagagaccg 1000

 gcatcaaatc caccacctat cagcaaccag gcaacaaaag gtaaacgtcc 1050

 aaaaaaagga atggcaacag ccaaacaacg tcttgggaag atccttaagt 1100

 tgaacagaaa tggccatgca cgtttctttg tgtgacagag ctgctgttgc 1150

 agccattctt ccctttggag accagtctag gggtgcagga gcctggagct 1200

 tccgctgtcc ccctgcctgg agcagtttgt gtgtatagta agaacactgc 1250

 ccgaagaaca gaatgaacct gatgctgcat tttcactgtg ccacacccac 1300

 tcagcaataa ccattttgga cctggtgggg gagaggaaga aggagggtag 1350

 aaccttaaaa agagaccttg aactggaaag ggtctcttgt cagggcttga 1400

 attttatttt gttgttggta gtgtcttgat gtattttcag tggtagggta 1450

 aagaattatc aataatttat ttaacagatt tttttttaaa gttaacagct 1500

 tttaaattct ttttttaaag ctatttattt ggaagatttc tggagaaata 1550

 tctcactaat ttagatgtaa gaatgtgaag gtttttaaat tatttttgat 1600

 agtgtgtgtg ttacatgtgg ggaagggcca cagtaacagt aactagtctg 1650

 gactcttaaa tttgatattc aggttaaagt cttaaacagg gatttgatgc 1700

 attaattatt ttaaattaag atgtatatga aaatcatttt attttatata 1750

 tttcatgtgt tttttataag ctattagctt cgcttttgct aacatccaag 1800

 gtgcatactg ttatccaggt tgattacctt atatcccacc ttccctctgc 1850

 actccccatc attttgtgat gacccagtaa gactcttctc tttgcaggga 1900

 aacactttcg tagccaatgt gtaagaactc catgaaagat ccctcatttc 1950

 tcatttcgtt tgacattgtg attttcttct caacattaaa aaaaataggc 2000

 ttttgcattt tcatttctgc tgatgatatc tgggtcccaa agagagcagc 2050

 tttaatatat ttttcctact tgtgggaaaa gtattataag tttggttaaa 2100

 ttgtcatgtt tatagttttt ccaagtacat ttgtaactac agcaggcctt 2150

 cttcgtactg ctgctgttgg acaacaggac tggcacctgc tgcagaggtt 2200

 ataccttatg atacttttat gctccatacc tgatttgttg ggaaatgtta 2250

 tttaggatat tcaaatctgc atcataagcc gtaatataat aggattaata 2300

 ctacattaag ttgtatagaa gcaagcatgt tggaatagat cttttgtgtg 2350

 tatttacttt ttttatttct taattttcta aagaattact taagatatgg 2400

 atttggagta aaatgggtgc ttttggcagt ttcttccatc tatcctaacc 2450

 tgaccagtac atattgaggt taagtatctg gttaaacttt aaggtattca 2500

 tttatctcct ttatgtatga tttttactaa atgccagttt tcatttgctt 2550

 atagtagctt ctattttccc ttttttccat ccatggcata aaaataagtg 2600

 atttctgggg gtggggcaga aatgttccca agtctgacaa tagagcattt 2650

 tacaaattcc tacaaagaaa atataggcaa atagataaaa tttattttta 2700

 tggagaagaa atatggccat attatggatt tgtctttttt ttactcagca 2750

 agatagcagg acttaccctt ctctattaag tatcacttga attgctaaga 2800

 agaaaaaagt ctgtaccatc atctttcatg gttgcattca aatgtatatt 2850

 ttcaaagaga aatacttctt gtgtccccat tccaaaatgt catgggataa 2900

 atatgaaata gtttatgaag tagcctttct ggttcagagt gactggacca 2950

 aagtctgaat cttatctggg tatcaggaaa aagaattttt atggaaatcc 3000

 ttagtgtcta taaacaaccc gtgtaaaccc tgtctacact atgccaaaac 3050

 cagtggaaag atgggtagag tcatcttatc tcaggatgtc aaaaatctgg 3100

 gtttgactga ttcccctacc ttcccacaca gtatattctt gtgatttttg 3150

 cttttctgta gatcctgagt cggtgttaca atagtcatgt ttttattttg 3200

 ggttaagaaa tacgaggtgt aagagctata atttcctttt cgtgttatat 3250

 catgatctgg gttttctttt ttcctttacg tttttcacag ctcttgagta 3300

 ttttctattt ttttctttag tcacaaaaat taaaattaaa ctttattttt 3350

 atgaattaaa atgaaattta atttattttt atgaattaaa attgtggcca 3400

 gtatccactg tgtccttagg ctgagaagta ctaatttgga gtagcccgtg 3450

 tgtggaattc taaagtgaag gtactgtgga ttcattttta gtagttttag 3500

 ccccttaata agtggctaag ttagaaaact ttcagcgagg taatagaacc 3550

 acttgaatag aatccatgtg tctttttctg aattggtgaa aattcggcca 3600

 ctgatccagt gactcctggt caaacgtctt ataacattac tggccataat 3650

 gcatcccttt atctcatgga aatggctgaa ctttgtggta gctgctgcga 3700

 gtacctgggc ttaacagtaa tagagaacct catttatacc atacagacac 3750

 agcaacttag gaagacagca ctgatagcat ttagctagtt gtaaccaaat 3800

 acaaatatgt aaaattgaga attatgatta acatatgcaa ctttagtaat 3850

 aggaatagat gataattttc ctgtattgtt tcaaataagt gactgttcag 3900

 ctgggatcca ttggattata atttacaatg tcacataata ttatgctttt 3950

 caatattgat gagtgatgta aacaatataa agttggcagt ttgtagtagt 4000

 tcagtatcct agaaatacat tgaacttcat aagtatcagt tcatttttaa 4050

 gcatacagaa ttgaagattc tgactgaaat cataaactca gaggaaacaa 4100

 gcccatcttt atcactaatt acttagcttg aatacttttc tatttttaaa 4150

 taatcctaat tattgccttt tcaatatagt ctactgtatt tatttatatg 4200

 ggatcaacag gtatttatca aacatctact gtgtgcccag cactacctag 4250

 tactgttggg gaacatcaat ttgcagttgt ggtctctgcc cttgaaggta 4300

 tcttctccag gaaattagca gtattatttt cacttctaag caaacatgag 4350

 caaaagagga cctgttcatt aaaaaacatg ctgacttttt tagtttcaac 4400

 tgagatatgc cactgtagaa gtgaaagtaa tttcacaatt aaagaaatgc 4450

 ttcaacttgg taattaatat ggtcatacag ggacttggtg tagcatgcaa 4500

 ggaagcagaa gacctgggct tttgtcgaag ttctgccatt taggtatcag 4550

 ctgtgtaacc ttgaataagt cacttaactc tttctcttag ttttctcatt 4600

 tgtaaatttg gattaaagtg tttattatga taatcaatta agaaaatctc 4650

 ttaacacttc atacatacag agaacttatc attaagttaa aactggcaat 4700

 taatgcacct ttatatatat ttttaaatga aaactaatac tattcatgat 4750

 gtttatttta tatcaaatat atgcccaggg catgctactt taaaaatccg 4800

 aggaatctcc aacaaggtgc tggattaaaa tcagattttg tgcttgaagt 4850

 ggaagaaaaa tgaagttgtt tatggataag agagtgagaa tgtgtatcct 4900

 caagtacgtt aagatgattt aactgaaaga tggctttagg tttttcttga 4950

 agaattagga aagtaccatc cccacagatt cagcatactc ttcaggtact 5000

 agataaaggt gaaggaagtc atggaattaa aatgacttag caactcccca 5050

 gggaacttgt ggggagaatg aggtggttag aaaggtgaga atgcacaaag 5100

 acagctctgg gttgggtacc aacagtttgc ttggtagaaa gaaaccagtg 5150

 taggaaagga gacgccacca gacatcttca acagacaaga ttctttctgc 5200

 ctttttcaaa agatgctctc tgcagcagta agactataga tagagttgat 5250

 tggaatatca tgtgacccag tatgctactg ctaggcataa ttatcaaaaa 5300

 ttcatttttc tcattaaata ttgttaattg ctcgccacat aaagagaagc 5350

 tagagctcac cagtcttggt ggtgtcctag accttcctct aaagcagtct 5400

 tgggaagctg gatcatcaga tctttagcct agacagagtg tcgctggtaa 5450

 ataaaggaga cacaggtaac ccagagtgga cagtgatttg cgtggggaga 5500

 cacagtggat ctggggcctc tgatactttg cttcctaaaa cagcccccag 5550

 ttttcggctt gccctatgag atgatgttca tgtgcttcct tgaaaccagg 5600

 tggaaagaaa ggggaagaat taattttctc attctgttgc tgttgaacgt 5650

 aatgtaatct taatactgta gccttcctag aagcccttcc ctctttttca 5700

 tgctgtaaag tcaaatattt gatatcctta acataaattt taaaaattaa 5750

 ggtcattagg aagcaaatgt ctatttccaa agcaatgagc ttgttgtgac 5800

 tgtgatttta ttcttctata gtattttttt cctcatttta attgagagga 5850

 gaaaataata ctcttttgca atatccttag gttctcccct tccccctggt 5900

 gccccttcta gtgtcttaag actttgtctt aacaagtata acattacatt 5950

 ttgttgttaa aacctttcga aactgtattc agtgattctt ccaagtttat 6000

 ctgctctgca ctatttcact aataaaccct ggctaccacg tagcccttga 6050

 tctccaagta gtttacctat gcaagacctg tgacactctg aattcacttc 6100

 tctttctttc agaaagtagt cataaatgga gcttaattat aaaggtaaaa 6150

 cttgtctcca accagtttca ttttggccat ttctttttca aaatgtcagc 6200

 tgttttcctc caagattttt caccaaaaca atgatcataa gtgctggaat 6250

 atataatact ttgcaggcat aaaataaccc agacatactc tcatatttct 6300

 ttggtgtatt ttggttggta aaacttacca gcattaaatg taaaatataa 6350

 tgaggagtta attccttacc tagaactatt tcttcctttt aagattcata 6400

 agtaaccttt tatttttaca gagctacgta taacttccac attacagtca 6450

 gggacctgag gtgtaactta ctaagtgaac cccaaggtta ttttatcttg 6500

 caaaagaaac ctaaaccaaa ctaagggcct tacagtttat ggttagactg 6550

 aatcaaaagc tataacctca atttttccaa aaacagcttc tgactgcaaa 6600

 agcaagtcat acagttgtta ggtatgaaat agcactgatc aggaaatgca 6650

 tcttcgcaga tggtatttcc ttcagaaaag acttttctac ttttaatata 6700

 aattaagcca taacagtttc atgctgtgga aagagggtga aaaggttcat 6750

 tttaagagat tatataatat gaactttcac atttactgtg aaatgtctaa 6800

 ctttgccagt gcttcagcaa gtttttttgg ggggtgatgg ggaggggtag 6850

 tattggtttt agaggtttca aatctgtgaa ctttggagag gggacagttg 6900

 ttggctctgg tatttactag ttttgtagta acgttttgct agcctgactg 6950

 acttttctta ctggttttta tgcccacggt ccgaggggac tgttcttctt 7000

 gtttggggtg tctgcggaat agcgtctcgt cttgtttgta taggcagtca 7050

 atgtgtgtga catgtgtgtc ctttcagtcc ggaagcccac tgtgtgacaa 7100

 tggcgtgggg tgtggctggg aggtggggtg ctgaagcttg aagagcattt 7150

 ctttgctgat tcataacagt atttcccatc ttttgcctgc aggcagggaa 7200

 agtgtacagt atttattttg tttctgtttt actttaaatt tgtaagtctt 7250

 taagtagctt acattgatta ttatagggga ggacaagtga cttgtttaaa 7300

 gttgtattta gtattctttc caatttctgt attttaaaat attgaaatta 7350

 aaattgtatt acttctgttt tgattttttt agcactcagt gtattttttg 7400

 ctcattttgt ttgaaagtat aaatgttgaa aattgtataa aatgcgtcct 7450

 tgaaagaaaa agaatctgaa ttctatatcc 7480

<210> 3663
<211> 377
<212> PRT
<213> Homo sapien

<400> 3663
 Ser Thr Val Pro Glu Trp Arg Ala Lys Asp Asn Asp Leu Arg Leu
   1               5                  10                  15

 Leu Leu Thr Asn Gly Arg Ile Ile Lys Asp Glu Arg Gln Pro Phe
                  20                  25                  30

 Ala Asp Gln Ser Leu Tyr Thr Ala Asp Ser Glu Asn Glu Glu Asp
                  35                  40                  45

 Lys Arg Arg Thr Lys Lys Ala Lys Met Lys Ile Glu Glu Ser Ser
                  50                  55                  60

 Gly Val Glu Gly Val Glu His Glu Glu Ser Gln Lys Pro Leu Asn
                  65                  70                  75

 Gly Phe Phe Thr Ser Val Lys Ser Glu Leu Arg Ser Arg Ser Ser
                  80                  85                  90

 Gly Tyr Ser Asp Ile Ser Glu Ser Glu Asp Ser Gly Pro Glu Cys
                  95                 100                 105

 Thr Ala Leu Lys Ser Ile Phe Thr Thr Glu Glu Ser Glu Ser Ser
                 110                 115                 120

 Gly Asp Glu Lys Lys Gln Glu Ile Thr Ser Asn Phe Lys Glu Glu
                 125                 130                 135

 Ser Asn Val Met Arg Asn Phe Leu Gln Lys Ser Gln Lys Pro Ser
                 140                 145                 150

 Arg Ser Glu Ile Pro Ile Lys Arg Glu Cys Pro Thr Ser Thr Ser
                 155                 160                 165

 Thr Glu Glu Glu Ala Ile Gln Gly Met Leu Ser Met Ala Gly Leu
                 170                 175                 180

 His Tyr Ser Thr Cys Leu Gln Arg Gln Ile Gln Ser Thr Asp Cys
                 185                 190                 195

 Ser Gly Glu Arg Asn Ser Leu Gln Asp Pro Ser Ser Cys His Gly
                 200                 205                 210

 Ser Asn His Glu Val Arg Gln Leu Tyr Arg Tyr Asp Lys Pro Val
                 215                 220                 225

 Glu Cys Gly Tyr His Val Lys Thr Glu Asp Pro Asp Leu Arg Thr
                 230                 235                 240

 Ser Ser Trp Ile Lys Gln Phe Asp Thr Ser Arg Phe His Pro Gln
                 245                 250                 255

 Asp Leu Ser Arg Ser Gln Lys Cys Ile Arg Lys Glu Gly Ser Ser
                 260                 265                 270

 Glu Ile Ser Gln Arg Val Gln Ser Arg Asn Tyr Val Asp Ser Ser
                 275                 280                 285

 Gly Ser Ser Leu Gln Asn Gly Lys Tyr Met Gln Asn Ser Asn Leu
                 290                 295                 300

 Thr Ser Gly Ala Cys Gln Ile Ser Asn Gly Ser Leu Ser Pro Glu
                 305                 310                 315

 Arg Pro Val Gly Glu Thr Ser Phe Ser Val Pro Leu His Pro Thr
                 320                 325                 330

 Lys Arg Pro Ala Ser Asn Pro Pro Pro Ile Ser Asn Gln Ala Thr
                 335                 340                 345

 Lys Gly Lys Arg Pro Lys Lys Gly Met Ala Thr Ala Lys Gln Arg
                 350                 355                 360

 Leu Gly Lys Ile Leu Lys Leu Asn Arg Asn Gly His Ala Arg Phe
                 365                 370                 375

 Phe Val


<210> 3664
<211> 5048
<212> DNA
<213> Homo sapien

<400> 3664
 tatctgtaag gacacattac aggcgtcaaa gagaaattcc tttggttcag 50

 aatgggccca ggccttgaag cctgctaaga ataccaaagc cagaagaaca 100

 ctaaagttct caaggtccct caatgatgtg ggtgagaagg cgcaggatac 150

 ttcagaaagt tttgcctatg tggaaagaac ttgttctgaa gggaaattaa 200

 tactccctca agatacgtgt ctcagaacta acaggtttca tcataaagaa 250

 aaaagaaccc tgaaccacaa acctcttggc aattccaaac attcttgtgt 300

 ttcatgcctt tctgccggtc gctcaactgc ctcagaggtg gaagctggca 350

 aggggggcag gcccggcctg ctgctggaag agaaggcgga tggtgaggcc 400

 acgtcccgaa gccggcaact gctccagtac ctgttctcac tctcgcacgg 450

 cttgagcgcc agcagcctgc acaggttcca tgagctggag agctgcgctg 500

 ctcgcctgca cactgccaag tcctccagcg ggctggcagg gagtatgggc 550

 ttctgctctg acgagatggg agacgacgat gtctttgagg acagcacatc 600

 tgcaaaactg aagagtaggg ttctgcgggc gcccctctgc tccacggaaa 650

 aggacagcga cctggattgt ccttctccct tctctgaaaa attacccccc 700

 atatctcccg tgtccacgtc aggggatgtc tgcaggatct gccactgtga 750

 aggagatgat gagagccccc tgatcacccc ctgccactgc acaggaagcc 800

 tccacttcgt gcaccaggcc tgcctgcagc agtggatcaa gagctccgac 850

 acgcgctgct gcgagctctg caagtatgag ttcatcatgg agaccaagct 900

 gaagccactg agaaaatggg agaagttgca gatgacgtcc agcgagcgca 950

 ggaagatcat gtgctcagtg acattccacg tcattgccat cacatgtgtg 1000

 gtctggtcct tgtatgtgct cattgaccgt actgctgagg agatcaagca 1050

 ggggcaggca acaggaatcc tagaatggcc cttttggact aaattggtgg 1100

 ttgtggccat cggcttcacc ggaggacttc tttttatgta tgttcagtgt 1150

 aaagtgtatg tgcaattgtg gaagagactc aaggcctata atagagtgat 1200

 ctatgttcaa aactgtccag aaacaagcaa aaagaatatt tttgaaaaat 1250

 ctccactaac agagcccaac tttgaaaata aacatggata tggaatctgt 1300

 cattccgaca caaactcttc ttgttgcaca gagcctgaag acaccggagc 1350

 agaaatcatt cacgtctgat tgtgtgcggg ttgtcatttt cctggacatc 1400

 catgaagagc tgaaggaaat tgtttactgc caattgtata cctttcttat 1450

 gtcctttaat agcatagact ggacaggtga ctatttatag tggcttctct 1500

 ttttctaaac cctccttagt ctcctagaaa accttcctgt gggccaggca 1550

 tgcctgggtc ctgcctctgc ctggcagctc tgtgggaaag tggaagaccc 1600

 catgatgaca tcatggggag ccagcagagt tcctgcccat ggtcttgagc 1650

 tgaatgagag aataaaatgc caatcccaag ggaagaggag gagcaggggt 1700

 gcccaggccc tgatacccag ccgcctccag cttgcagtgg tccccagcct 1750

 ggagcagagc attggggagt gtctagccat gacgagaaga ttccctctgc 1800

 atcacggcga accccaggag atggtattga aacagacccc caaacacaga 1850

 ctcctgcctg ccctctgccg atgctgcctc ctccatgctc ttgagcaggt 1900

 ggagccatgg tgctctgtgg tggcgcatga ttcactgagc aaacagcact 1950

 ttacagaaga aaatctttat tttgtaatat gtgtgtccag cgggattgac 2000

 actcaaaaaa agtctcactt agaaatcttc ccttccttac ctttgtatct 2050

 cctttacatc atgagagatc aaaaatccat tttgccttac atatgctaag 2100

 aagcgtggca ttctttctgt tcataaaaca gactcatgac ttttaagaca 2150

 ggacaagcag gccagaggct ttttttttaa tcacagatct catgggaatt 2200

 agtggatgct aaatggcaat taaagcatga ttcctatgct tttgagcctg 2250

 ttttatgaca aggtgttact ttgtaggcct ggcccataca tttctttttt 2300

 gtcaacactg aaaaagaaca gtttctgaga tcgaaatgga aggaaaggaa 2350

 gtgagtaatg acaacaaaac tgaatattta aaaaatattc ctttatagtt 2400

 aaatctctcc agttggtgtt ggcttcacat tgaaagagca gccatgtgcc 2450

 accctggccg gggtgtgtgc actgcatgca ggttctccct tgcatgcaag 2500

 atgggtgctg gcccactgtg aggcttctgc tcggggaagt tctgtggagt 2550

 cactaccagg gccaagaggc aggtgggctg gctctgggac gagggccagg 2600

 tgtgagcaaa ctgccagggt ccgctgtgcc actgctcccc ggccacatgc 2650

 ccgcccagct gtcgccttaa ccagactgaa cagacaggat ccttcagggc 2700

 ccttggcccc actctcagtg cattctgtca tcagggatta ccacctgtac 2750

 cattttcata aaacaaaacc aaaatcacta ccatcaaatg gccttgtccc 2800

 tctaaaaagt ctgcttaaaa ttctgttttt aaaacccagt ttcctagttt 2850

 tccaggcaaa tagttacctc cgggaaagtt gctggggggg cctgaagcac 2900

 aatgtagcgc agatgcttcc tttccaggcc attctctcac ccagcctgca 2950

 cggaggagat gggagatgct gggggtcctg ccctcagtct ttttgggcct 3000

 taggcgtttc gttcatcctg ctaaggggat gaagcaaaca cgaggtgatt 3050

 cctttgcctt tcagagtgga agccctggag tttgttttga aggccaggag 3100

 gctgaaggat ctctaagcta cggtgtgggc ttaatagcag caggctttgt 3150

 cctcctgtct cctccaagcc agtgtctgat tccttggcaa cacaggtctt 3200

 agtctgtgga gtggctctgc tgtggccttc ctctggccgg gcaggcactg 3250

 tccagccata gccagctcct gagaataggt cagcctctcc tttctgtctc 3300

 ccagggcaca tccagcccgt gcctgtgttc actgtgcccc gaagtgcaat 3350

 tacccatacc ccttctcagc ctggggaccc caggcaacca cagactgtcc 3400

 actcagggga gctgaatccc aggtcagccc tgccaatgtc ccttaggaac 3450

 tgcccaggca aggcccctgg ttttgtatac ttgttcctgc cacccagcag 3500

 tagatgagtg tttcaggtga agaccaggat agattttcta agtgtgaatc 3550

 cccacttcac atatggaacc ccttatgctg aacttgaaaa gcaccaagac 3600

 ttcctgtaga caagaaagtg cttaggtagg gacagcccct gggcatccca 3650

 cccaatgtag ctggcacccc actatggcaa aggtgccttg ataactgagc 3700

 cctgtatccc tcccatgccc agccagattc tcatgggaag ccctctccct 3750

 tcttttctgc ctaacaccat ctcatcgttt ctggcctcac tgtggacaat 3800

 ccacacacat tcttctttcc tctcctggcg gggcacagag ccaccccctt 3850

 gccttttctt ttcttgaagg ttctagttca gctcctgatt catcagaccc 3900

 ttctagcccc ctgcatctag cagtgaagca tgaagcctgg tggggatgtg 3950

 gtactcccat ctggtgtggc caccagctct gccaatgttc ctgtagcctt 4000

 ggaaaacttg ctctctcggt tcttttgggt gctgtgtact ccccagcttc 4050

 cccccttccc cccccatttt gcacctgggt ttagtgaaag gatggcattt 4100

 ggttgaccca tatagaaacc cagaatgagg tctcagggcc aggaggcctg 4150

 gtatttgtag gccagggaag gggaagaggc aagtggtctg gggtatcacc 4200

 agccagccct ctctgatttg gcctctactc cccataagtc acagtaccat 4250

 aagcaggctt ctggcctcag caatttggtc tttgtgccca agtttattgt 4300

 gagaatttcc tgaaaactct ataaaaggtc tcttcctact gtaggcctct 4350

 aatgtttctc ccctttttgc ttcagtccac tcttcagtct tgtaggccta 4400

 gttttcaaac ctgcacatgt gtcctacctg gccacaggca tgcaggcctc 4450

 aggcagctgg gccagtttgg gagcctcggg tgatgtctgc acgatctggg 4500

 gctgcctctg cacccctgct gtgggcttca gggttggaga agggctggga 4550

 ccaaccgggt gagatccaca agtctctgga tgtggctgaa ggcaaataca 4600

 caattgaagt actttctgtt ttgaagtgct ttcccttttg aatctggttt 4650

 gaaacatgca gcttctgtct ctagcccaag gaaagaccaa aacataggga 4700

 aataaaagca tttatctttg tcttggaagt aattgttgaa gttgtgcagt 4750

 tgatcagtgc acagttagat gcaatgttta tagaaattga ttgttaaacc 4800

 aaatttacac tggcatgtgt ggtgtagttt ctaaaaggca cttcacattt 4850

 gaaatttttc ttaccttaga aagtttctag tgatctaaat gtctagtttt 4900

 gtattctttt gtgtgtgttc actgtttctc agtattacca cttgaataat 4950

 tctctgtaca ggggggtttg tgctatacac tgggatgtct aattgcagca 5000

 ataaagcctt tctttaaaaa gcaaaaaaaa aaaaaaaaaa aaaaaaaa 5048

<210> 3665
<211> 455
<212> PRT
<213> Homo sapien

<400> 3665
 Ile Cys Lys Asp Thr Leu Gln Ala Ser Lys Arg Asn Ser Phe Gly
   1               5                  10                  15

 Ser Glu Trp Ala Gln Ala Leu Lys Pro Ala Lys Asn Thr Lys Ala
                  20                  25                  30

 Arg Arg Thr Leu Lys Phe Ser Arg Ser Leu Asn Asp Val Gly Glu
                  35                  40                  45

 Lys Ala Gln Asp Thr Ser Glu Ser Phe Ala Tyr Val Glu Arg Thr
                  50                  55                  60

 Cys Ser Glu Gly Lys Leu Ile Leu Pro Gln Asp Thr Cys Leu Arg
                  65                  70                  75

 Thr Asn Arg Phe His His Lys Glu Lys Arg Thr Leu Asn His Lys
                  80                  85                  90

 Pro Leu Gly Asn Ser Lys His Ser Cys Val Ser Cys Leu Ser Ala
                  95                 100                 105

 Gly Arg Ser Thr Ala Ser Glu Val Glu Ala Gly Lys Gly Gly Arg
                 110                 115                 120

 Pro Gly Leu Leu Leu Glu Glu Lys Ala Asp Gly Glu Ala Thr Ser
                 125                 130                 135

 Arg Ser Arg Gln Leu Leu Gln Tyr Leu Phe Ser Leu Ser His Gly
                 140                 145                 150

 Leu Ser Ala Ser Ser Leu His Arg Phe His Glu Leu Glu Ser Cys
                 155                 160                 165

 Ala Ala Arg Leu His Thr Ala Lys Ser Ser Ser Gly Leu Ala Gly
                 170                 175                 180

 Ser Met Gly Phe Cys Ser Asp Glu Met Gly Asp Asp Asp Val Phe
                 185                 190                 195

 Glu Asp Ser Thr Ser Ala Lys Leu Lys Ser Arg Val Leu Arg Ala
                 200                 205                 210

 Pro Leu Cys Ser Thr Glu Lys Asp Ser Asp Leu Asp Cys Pro Ser
                 215                 220                 225

 Pro Phe Ser Glu Lys Leu Pro Pro Ile Ser Pro Val Ser Thr Ser
                 230                 235                 240

 Gly Asp Val Cys Arg Ile Cys His Cys Glu Gly Asp Asp Glu Ser
                 245                 250                 255

 Pro Leu Ile Thr Pro Cys His Cys Thr Gly Ser Leu His Phe Val
                 260                 265                 270

 His Gln Ala Cys Leu Gln Gln Trp Ile Lys Ser Ser Asp Thr Arg
                 275                 280                 285

 Cys Cys Glu Leu Cys Lys Tyr Glu Phe Ile Met Glu Thr Lys Leu
                 290                 295                 300

 Lys Pro Leu Arg Lys Trp Glu Lys Leu Gln Met Thr Ser Ser Glu
                 305                 310                 315

 Arg Arg Lys Ile Met Cys Ser Val Thr Phe His Val Ile Ala Ile
                 320                 325                 330

 Thr Cys Val Val Trp Ser Leu Tyr Val Leu Ile Asp Arg Thr Ala
                 335                 340                 345

 Glu Glu Ile Lys Gln Gly Gln Ala Thr Gly Ile Leu Glu Trp Pro
                 350                 355                 360

 Phe Trp Thr Lys Leu Val Val Val Ala Ile Gly Phe Thr Gly Gly
                 365                 370                 375

 Leu Leu Phe Met Tyr Val Gln Cys Lys Val Tyr Val Gln Leu Trp
                 380                 385                 390

 Lys Arg Leu Lys Ala Tyr Asn Arg Val Ile Tyr Val Gln Asn Cys
                 395                 400                 405

 Pro Glu Thr Ser Lys Lys Asn Ile Phe Glu Lys Ser Pro Leu Thr
                 410                 415                 420

 Glu Pro Asn Phe Glu Asn Lys His Gly Tyr Gly Ile Cys His Ser
                 425                 430                 435

 Asp Thr Asn Ser Ser Cys Cys Thr Glu Pro Glu Asp Thr Gly Ala
                 440                 445                 450

 Glu Ile Ile His Val
                 455

<210> 3666
<211> 2239
<212> DNA
<213> Homo sapien

<400> 3666
 cgctccggct cctggggctc cccgcagacg ctgcttttct tgctccactg 50

 ggggtgcctc ttcctgggcg cccgccgcct gcatcctgct cgccctgtct 100

 gggaatgggg ccgcccccgg gcttgggccg gcccggctgg ggcccccgag 150

 gcgcttccgc cccgtagtga ccgcctggtg ccgccccccc ccaggatgaa 200

 gggcggcgag ggggacgcgg gcgagcaggc cccgctgaac cctgagggcg 250

 agagccctgc aggctcggcc acgtaccggg agttcgtgca ccgcggctac 300

 ctggacctca tgggggccag tcagcactcg ctgcgggcgc tcagctggcg 350

 ccgcctctac ctcagccggg ccaagctcaa agcttccagc cgcacgtctg 400

 ccttgctctc gggcttcgcc atggtggcca tggtggaggt gcagctggag 450

 agtgaccacg agtacccacc aggcctgctg gtggccttca gtgcctgcac 500

 caccgtgctg gtggctgtgc acctctttgc actcatggtc tccacgtgtc 550

 tgctgcccca cattgaagct gtgagcaaca tccacaacct caactctgtc 600

 caccagtcgc cacaccagag actgcaccgc tacgtggagc tggcctgggg 650

 cttctccact gccctgggca cctttctctt ccttgctgaa gttgtcctgg 700

 ttggttgggt caagtttgtg cccattgggg ctcccttgga cacaccgacc 750

 cccatggtgc ccacatcccg ggtgcccggg actctggcac cagtggctac 800

 ctcccttagt ccagcttcca atctcccacg gtcctctgcg tctgcagcac 850

 cgtcccaggc tgagccagcc tgcccacccc ggcaagcctg tggtggtggt 900

 ggggcccatg ggccaggctg gcaagcagcc atggcctcca cagccatcat 950

 ggtacccgtg gggctcgtgt ttgtggcctt tgccctgcat ttctaccgct 1000

 ccttggtggc acacaagaca gaccgctaca agcaggaact agaggaactg 1050

 aatcgcctgc agggggagct gcaggctgtg tgagactggt gttagccacc 1100

 gctcactgca agcactgcct ccctccgggg tctgtaagag gccgcagggg 1150

 cctacagacc tcatcccccc atcccctggc tggagccact tccagtggcc 1200

 actctcaggc agagttcaga ttcctgcccg cagggtcctc tgggctgggc 1250

 cttggggcag ctcccacatt cccagggatt ttccccatca gtctgtccct 1300

 tgggttttgc aagctactct gcacctgggc tggcctcagt tgaaggatca 1350

 tgcagtagat agaggggagg cagggagagc ttgtgggacc ttcagtgctg 1400

 actttagcca ccatttccat tcctatacag gatgtgaagg tcagaaggca 1450

 gccaattgtt ggtttaattt tttttttttt tgagacagtc tgtttcccag 1500

 gctggagtgt agtgatacag tcacagctca ctgtagcctc gaccttccag 1550

 gctcaaaaga tgctcccacc acagcctccc aggtagtgag tagctggtac 1600

 tacaggtgtg tgctgccaca cccgactaat ttttttgtag agacggggtt 1650

 tcgctgttcc caggctggtc tcaaactcct gggctcaagt gaacctcccg 1700

 cctcggcctc ccaaagtgct gggattcctt tctttatttc tgtagaatct 1750

 attttatggt tggcattttg ggggaagatt tcgatgggtt ccacattctt 1800

 gctttagttg ttgtagaggg atttgggtgt ttctacccaa ggcattggtc 1850

 tagcttttcc tacaatgaac ctatctttgg aggtttaagc tccccacctt 1900

 cccccactgt ggtgacctgt ggccacttgc agaagggatg gtgcctgacc 1950

 cactgcccta gccccacgct atgcaccaaa cttgttctcc ccgtcctggt 2000

 ccagggctgg ggtctttaga gactgacagc ctctgcccca ggcctgagtc 2050

 cttagcaagg gttgggtaag gaggttttaa gggagaaggt ccagtcctta 2100

 gcccttgaaa tacaaagctc ttctgacact gaatttggat gcaccttgtt 2150

 ttatataata aatcgtgttt cacagaaaaa aaaaaaaaaa aaaaaaaaaa 2200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2239

<210> 3667
<211> 295
<212> PRT
<213> Homo sapien

<400> 3667
 Met Lys Gly Gly Glu Gly Asp Ala Gly Glu Gln Ala Pro Leu Asn
   1               5                  10                  15

 Pro Glu Gly Glu Ser Pro Ala Gly Ser Ala Thr Tyr Arg Glu Phe
                  20                  25                  30

 Val His Arg Gly Tyr Leu Asp Leu Met Gly Ala Ser Gln His Ser
                  35                  40                  45

 Leu Arg Ala Leu Ser Trp Arg Arg Leu Tyr Leu Ser Arg Ala Lys
                  50                  55                  60

 Leu Lys Ala Ser Ser Arg Thr Ser Ala Leu Leu Ser Gly Phe Ala
                  65                  70                  75

 Met Val Ala Met Val Glu Val Gln Leu Glu Ser Asp His Glu Tyr
                  80                  85                  90

 Pro Pro Gly Leu Leu Val Ala Phe Ser Ala Cys Thr Thr Val Leu
                  95                 100                 105

 Val Ala Val His Leu Phe Ala Leu Met Val Ser Thr Cys Leu Leu
                 110                 115                 120

 Pro His Ile Glu Ala Val Ser Asn Ile His Asn Leu Asn Ser Val
                 125                 130                 135

 His Gln Ser Pro His Gln Arg Leu His Arg Tyr Val Glu Leu Ala
                 140                 145                 150

 Trp Gly Phe Ser Thr Ala Leu Gly Thr Phe Leu Phe Leu Ala Glu
                 155                 160                 165

 Val Val Leu Val Gly Trp Val Lys Phe Val Pro Ile Gly Ala Pro
                 170                 175                 180

 Leu Asp Thr Pro Thr Pro Met Val Pro Thr Ser Arg Val Pro Gly
                 185                 190                 195

 Thr Leu Ala Pro Val Ala Thr Ser Leu Ser Pro Ala Ser Asn Leu
                 200                 205                 210

 Pro Arg Ser Ser Ala Ser Ala Ala Pro Ser Gln Ala Glu Pro Ala
                 215                 220                 225

 Cys Pro Pro Arg Gln Ala Cys Gly Gly Gly Gly Ala His Gly Pro
                 230                 235                 240

 Gly Trp Gln Ala Ala Met Ala Ser Thr Ala Ile Met Val Pro Val
                 245                 250                 255

 Gly Leu Val Phe Val Ala Phe Ala Leu His Phe Tyr Arg Ser Leu
                 260                 265                 270

 Val Ala His Lys Thr Asp Arg Tyr Lys Gln Glu Leu Glu Glu Leu
                 275                 280                 285

 Asn Arg Leu Gln Gly Glu Leu Gln Ala Val
                 290                 295

<210> 3668
<211> 3033
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 712-736
<223> Unknown base

<400> 3668
 gcgagacgtc attttgcgtc gcctcgggca gggtagccag cggctgcatc 50

 tgaggcggac gccgcagtgt agggcacacc ctgagggtag cgagagacgt 100

 gacaggaccg agcagctggg ggctgcagcc tgctctgtcc ccaccgatcc 150

 cagagagagg ctgtgagtct ggatctgggc gttcgcaccc tgagagaggg 200

 ggtcaaagct cccctgcggc cccgaggaag aagagcaagg ttgaggacag 250

 cctcgggtca ccagagtagt ttggaggcag gcctgcaggc gcgtccccgc 300

 tcctcagctc caagctgacg tatctacacc tgccggcggg cattaagatg 350

 gctggttatg ccactactcc cagccccatg cagacccttc aggaggaagc 400

 ggtgtgtgcc atctgcttgg attacttcaa ggaccccgtg tccatcagct 450

 gtgggcacaa cttctgccga gggtgtgtga cccagctgtg gagtaaggag 500

 gacgaggagg accagaacga ggaggaagat gaatgggagg aggaggagga 550

 cgaggaagcg gtgggggcca tggatggatg ggacggctcc attcgagagg 600

 tgttgtatcg ggggaatgct gacgaagagt tgttccaaga ccaagatgac 650

 gatgaactct ggctcggtga cagtggtata actaattggg acaacgtaga 700

 ctatatgtgg gnnnnnnnnn nnnnnnnnnn nnnnnntcag gactattacc 750

 taggaggctt gagacctgac ctgagaattg atgtctaccg agaagaagaa 800

 atactggaag catacgatga ggacgaagat gaagagctgt atcctgacat 850

 ccacccgcct ccttccttgc cccttccagg gcagttcacc tgcccccagt 900

 gccgaaagag ctttacacgt cgcagctttc gtcccaactt gcagctggcc 950

 aacatggtcc agataattcg ccagatgtgc cccactcctt atcggggaaa 1000

 ccggagtaat gatcagggca tgtgctttaa acaccaggaa gccctgaaac 1050

 tcttctgtga ggtggacaaa gaggccatct gtgtggtgtg ccgagaatcc 1100

 aggagccaca aataaattaa ggaattccag aatttcttca tctactttct 1150

 gcacgtcttg actctgagat taatgagctg tgatatatcc aacttcagat 1200

 tctttaaaaa catcaagctc gcaaagaggc tgaggcacgg agaatgacat 1250

 gaacctggga aggcggaggc ttgcagtaaa gccgaggagc tgaggcccct 1300

 gcaactccag cctgggcaat agagcacaga gctccatttc caaaaaaaaa 1350

 aaaaatcggc tcatctttta ttgctgttgg ttgagatgaa tctactgatg 1400

 aagaaaactg tactttgctt acattcagaa taaggctttc aaaactgtgg 1450

 gtgtgctgtt ttcgtgagcc ttctacttga ccaccaaaga cagtattttt 1500

 gcagctgtat caaatgaacc gagttggagg aaattgtata ggagtatatc 1550

 ttaatggcac tacagcaaac tgtgttaaat ttgggttttt ggcaaagatt 1600

 gaagaaaact ggtattcaag atgtactgca gctgtcacca ccaagcatga 1650

 actttcactg attacccata acctactgga aatcttcagc cttgctgtca 1700

 gcatagacca ctgtgagaaa cagtacattc cattccagtt tgccctgctt 1750

 tttgaagatc taaatgccat tccatgtttt ctgttacata ttgaagtttc 1800

 ttggttgcca aagaaaaacg gattctgctg aacttgtgga cagaacaacc 1850

 ccaaggttgg aagaacaatg aaaaataatc tatacttgaa catttcaaaa 1900

 gttaaaattt tcaacagagt tttaacacac tgaagcttaa aatacattga 1950

 cactgaaatg tcaatgggca aacaccaatt tcgccgttca ttatgaaata 2000

 catcaaacaa aacttgccaa aaatacaacc ataaaaatat agcaaatgta 2050

 tgtatgagca aactaatgct aaaaatgtct aattttcttg gctagtcttt 2100

 caaggaccag attcatgagt gttatttgaa gggaaaaagt gaaatacttg 2150

 gaattatttt gagtgatgtg ctcctgagct tgttcttaaa atctaccagt 2200

 ggtagctttt ggaaagaatg tgtttcatac cgatgtgcag gcctcactgg 2250

 aagagcttca agaggagttt gtgaaactca aagtctaatg gttttgatta 2300

 gaaacttcca ggcaaatact ccagagaaac ttgggtgtaa aatgactaaa 2350

 cagatgaaaa ggctttatcc actattccat ttgctcctta caccttaaaa 2400

 agctttttta ttttttaatg ttttgatata tctagctttg gggagaaagc 2450

 agtgcaagag tgttattaaa agcagcttgt gttttcttgc acctttcaca 2500

 ccacccagga aagaaaagtt caggcttaac agtgacatgg ctatcacatc 2550

 atctgaataa attttttcct tctaaaatta ctactgcttt cattaatttc 2600

 aatcatgata cttaattttg aaattgtaaa tggaggggca aatgtgagat 2650

 tttcaggtat atgaaaagta gaagtgtggg ttacaaaaac attgaggaaa 2700

 aacatacagc tcacctgttt attgaatgtc ttccctatta ggttcagctg 2750

 ttcactgctg tatcacaagt cagactgttt aaacttgttc ctctacttct 2800

 gtggctgtac cctggatctc atcttcagat tggctacaca tctgaaatca 2850

 actcccattg cactatgacc ttagctctta gccttccaat acacttaagc 2900

 acactccaat tacacctgcc cttcagcttt agggagccca ctgtttcact 2950

 gactccatat tttttccttc ccaatttatc agacatttaa cagccttact 3000

 atcctactga gcctagactg catgattcat ttt 3033

<210> 3669
<211> 255
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 122-130
<223> unknown amino acid

<220>
<221> Unsure
<222> 712-736
<223> Unknown amino acid

<400> 3669
 Met Ala Gly Tyr Ala Thr Thr Pro Ser Pro Met Gln Thr Leu Gln
   1               5                  10                  15

 Glu Glu Ala Val Cys Ala Ile Cys Leu Asp Tyr Phe Lys Asp Pro
                  20                  25                  30

 Val Ser Ile Ser Cys Gly His Asn Phe Cys Arg Gly Cys Val Thr
                  35                  40                  45

 Gln Leu Trp Ser Lys Glu Asp Glu Glu Asp Gln Asn Glu Glu Glu
                  50                  55                  60

 Asp Glu Trp Glu Glu Glu Glu Asp Glu Glu Ala Val Gly Ala Met
                  65                  70                  75

 Asp Gly Trp Asp Gly Ser Ile Arg Glu Val Leu Tyr Arg Gly Asn
                  80                  85                  90

 Ala Asp Glu Glu Leu Phe Gln Asp Gln Asp Asp Asp Glu Leu Trp
                  95                 100                 105

 Leu Gly Asp Ser Gly Ile Thr Asn Trp Asp Asn Val Asp Tyr Met
                 110                 115                 120

 Trp Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Gln Asp Tyr Tyr Leu
                 125                 130                 135

 Gly Gly Leu Arg Pro Asp Leu Arg Ile Asp Val Tyr Arg Glu Glu
                 140                 145                 150

 Glu Ile Leu Glu Ala Tyr Asp Glu Asp Glu Asp Glu Glu Leu Tyr
                 155                 160                 165

 Pro Asp Ile His Pro Pro Pro Ser Leu Pro Leu Pro Gly Gln Phe
                 170                 175                 180

 Thr Cys Pro Gln Cys Arg Lys Ser Phe Thr Arg Arg Ser Phe Arg
                 185                 190                 195

 Pro Asn Leu Gln Leu Ala Asn Met Val Gln Ile Ile Arg Gln Met
                 200                 205                 210

 Cys Pro Thr Pro Tyr Arg Gly Asn Arg Ser Asn Asp Gln Gly Met
                 215                 220                 225

 Cys Phe Lys His Gln Glu Ala Leu Lys Leu Phe Cys Glu Val Asp
                 230                 235                 240

 Lys Glu Ala Ile Cys Val Val Cys Arg Glu Ser Arg Ser His Lys
                 245                 250                 255

<210> 3670
<211> 817
<212> DNA
<213> Homo sapien

<400> 3670
 aaattgcaga agttacttat tcttttaaga ggtctgcctg gttctgggaa 50

 aacaacattg tctcgaattc tgcttggtca gaatcgtgat ggcattgtgt 100

 tcagcactga tgactatttt caccatcaag atgggtacag gtataatgtt 150

 aatcaacttg gtgatgccca tgactggaac cagaacagag gtttgttttg 200

 ggctaagtgt cccaggatag aatatttggc taggagtcaa aagacctaga 250

 ttttattttc agcttaggtt tttaccagct gaatgactgt aggcaagccg 300

 tttaaatagc tttgagacct aatttctcca tctgttagag gtggtgataa 350

 ttatacttgc cctacctgat cagggttttt gtgaaaagca gagaatttag 400

 ataaaacgct ttgtaaactg taaatagttt atcagtataa gctggtaaaa 450

 taatagcagc atgggatatt ttaagaggct ttattttata cttgatgagt 500

 aaattcagag aactttgaat ctgtaccatt gttatgtagt cccaaagtta 550

 tttccccgag aataatgcta atgttttcca aggcttaata tactggttgt 600

 gaatattaaa agtttttctc attgatattg ctctacaaga aacctactta 650

 atacattttt tagcggacat gggtcaattt ctgtttatca ttaatagggg 700

 ttcttaacct gggctacact tttgaatttc ttggggactt taaaaaaaag 750

 caaaaaaatc tatgtcgggt gcggagaaag aggtaatgaa atggcagaat 800

 tcgatagcaa gcttatc 817

<210> 3671
<211> 82
<212> PRT
<213> Homo sapien

<400> 3671
 Lys Leu Gln Lys Leu Leu Ile Leu Leu Arg Gly Leu Pro Gly Ser
   1               5                  10                  15

 Gly Lys Thr Thr Leu Ser Arg Ile Leu Leu Gly Gln Asn Arg Asp
                  20                  25                  30

 Gly Ile Val Phe Ser Thr Asp Asp Tyr Phe His His Gln Asp Gly
                  35                  40                  45

 Tyr Arg Tyr Asn Val Asn Gln Leu Gly Asp Ala His Asp Trp Asn
                  50                  55                  60

 Gln Asn Arg Gly Leu Phe Trp Ala Lys Cys Pro Arg Ile Glu Tyr
                  65                  70                  75

 Leu Ala Arg Ser Gln Lys Thr
                  80

<210> 3672
<211> 5414
<212> DNA
<213> Homo sapien

<400> 3672
 ttgagaaacg aggtctaggg ttggcaggca atacaataca actcttgatg 50

 cctctcattc ctctgtcagg ctccacaagg acactttaag gactaatttg 100

 atttaaatca attcattaaa aaatatctat agcttttagc tagaagaacc 150

 ccaaggagtg attattttgc aatagggctg agttgggccg ggcatggtgg 200

 ctcacacctg taatcccagc actttggggg ccgcgcgtcg gagtttcccc 250

 ctttctaggg tgaggatggt tctacacagc cacccggagt tccttagttg 300

 aaaggtgcgc cctgctgtga cagcatggac accacgttgc tgaaaacatg 350

 ctttgggact gccactgaat ttatcttttg cggttttatg acaaagttat 400

 tagtagtttc ccttttttga attagtattt tgaagttaat atcacaatga 450

 gttcaggctt atggagccaa gaaaaagtca cttcacccta ctgggaagag 500

 cggatttttt acttgcttct tcaagaatgc agcgttacag acaaacaaac 550

 acaaaagctc cttaaagtac cgaagggaag tataggacag tatattcaag 600

 atcgttctgt ggggcattca aggattcctt ctgcaaaagg caagaaaaat 650

 cagattggat taaaaattct agagcaacct catgcagttc tctttgttga 700

 tgaaaaggat gttgtagaga taaatgaaaa gttcacagag ttacttttgg 750

 caattaccaa ttgtgaggag aggttcagcc tgtttaaaaa cagaaacaga 800

 ctaagtaaag gcctccaaat agacgtgggc tgtcctgtga aagtacagct 850

 gagatctggg gaagaaaaat ttcctggagt tgtacgcttc agaggacccc 900

 tgttagcaga gaggacagtc tccggaatat tctttggagt tgaattgctg 950

 gaagaaggtc gtggtcaagg tttcactgac ggggtgtacc aagggaaaca 1000

 gctttttcag tgtgatgaag attgtggcgt gtttgttgca ttggacaagc 1050

 tagaactcat agaagatgat gacactgcat tggaaagtga ttacgcaggt 1100

 cctggggaca caatgcaggt cgaacttcct cctttggaaa taaactccag 1150

 agtttctttg aaggttggag aaacaataga atctggaaca gttatattct 1200

 gtgatgtttt gccaggaaaa gaaagcttag gatattttgt tggtgtggac 1250

 atggataacc ctattggcaa ctgggatgga agatttgatg gagtgcagct 1300

 ttgtagtttt gcgtgtgttg aaagtacaat tctattgcac atcaatgata 1350

 tcatcccaga gagtgtgacg caggaaagga ggcctcccaa acttgccttt 1400

 atgtcaagag gtgttgggga caaaggttca tccagtcata ataaaccaaa 1450

 ggctacagga tctacctcag accctggaaa tagaaacaga tctgaattat 1500

 tttatacctt aaatgggtct tctgttgact cacaaccaca atccaaatca 1550

 aaaaatacat ggtacattga tgaagttgca gaagaccctg caaaatctct 1600

 tacagagata tctacagact ttgaccgttc ttcaccacca ctccagcctc 1650

 ctcctgtgaa ctcactgacc accgagaaca gattccactc tttaccattc 1700

 agtctcacca agatgcccaa taccaatgga agtattggcc acagtccact 1750

 ttctctgtca gcccagtctg taatggaaga gctaaacact gcacccgtcc 1800

 aagagagtcc acccttggcc atgcctcctg ggaactcaca tggtctagaa 1850

 gtgggctcat tggctgaagt taaggagaac cctcctttct atggggtaat 1900

 ccgttggatc ggtcagccac caggactgaa tgaagtgctc gctggactgg 1950

 aactggaaga tgagtgtgca ggctgtacgg atggaacctt cagaggcact 2000

 cggtatttca cctgtgccct gaagaaggcg ctgtttgtga aactgaagag 2050

 ctgcaggcct gactctaggt ttgcatcatt gcagccggtt tccaatcaga 2100

 ttgagcgctg taactcttta gcatttggag gctacttaag tgaagtagta 2150

 gaagaaaata ctccaccaaa aatggaaaaa gaaggcttgg agataatgat 2200

 tgggaagaag aaaggcatcc agggtcatta caattcttgt tacttagact 2250

 caaccttatt ctgcttattt gcttttagtt ctgttctgga cactgtgtta 2300

 cttagaccca aagaaaagaa cgatgtagaa tattatagtg aaacccaaga 2350

 gctactgagg acagaaattg ttaatcctct gagaatatat ggatatgtgt 2400

 gtgccacaaa aattatgaaa ctgaggaaaa tacttgaaaa ggtggaggct 2450

 gcatcaggat ttacctctga agaaaaagat cctgaggaat tcttgaatat 2500

 tctgtttcat catattttaa gggtagaacc tttgctaaaa ataagatcag 2550

 caggtcaaaa ggtacaagat tgttacttct atcaaatttt tatggaaaaa 2600

 aatgagaaag ttggcgttcc cacaattcag cagttgttag aatggtcttt 2650

 tatcaacagt aacctgaaat ttgcagaggc accatcatgt ctgattattc 2700

 agatgcctcg atttggaaaa gactttaaac tatttaaaaa aatttttcct 2750

 tctctggaat taaatataac agatttactt gaagacactc ccagacagtg 2800

 ccggatatgt ggagggcttg caatgtatga gtgtagagaa tgctacgacg 2850

 atccggacat ctcagctgga aaaatcaagc agttttgtaa aacctgcaac 2900

 actcaagtcc accttcatcc gaagaggctg aatcataaat ataacccagt 2950

 gtcacttccc aaagacttac ccgactggga ctggagacac ggctgcatcc 3000

 cttgccagaa tatggagtta tttgctgttc tctgcataga aacaagccac 3050

 tatgttgctt ttgtgaagta tgggaaggac gattctgcct ggctcttctt 3100

 tgacagcatg gccgatcggg atggtggtca gaatggcttc aacattcctc 3150

 aagtcacccc atgcccagaa gtaggagagt acttgaagat gtctctggaa 3200

 gacctgcatt ccttggactc caggagaatc caaggctgtg cacgaagact 3250

 gctttgtgat gcatatatgt gcatgtacca gagtccaaca atgagtttgt 3300

 acaaataact ggggtcatcg ggaaaggcaa agaaactgaa ggcagagtcc 3350

 taacgttgca tcttattcga gctggcagtt ctgttcacgt ccattgccgg 3400

 caatggatgt ctttgtggtg atgatccttc agaaaaggat gcctctgttt 3450

 aaaaacaaat tgcttttgtg tccctgaagt atttaataag aagcattttg 3500

 cactctagaa agtatgtttg tgttggtttt ttaagaagtc taaatgaagt 3550

 tattaatacc tgaagcttta agttaagtgc attgatcata tgatattttt 3600

 ggaagcatac aattttaatt gtggaagttt aaagcctctt ttagtccatt 3650

 gagaatgtaa ataaatgtgt cttctttatg gaccaaggat atgaaatcat 3700

 ttttcttttg tagctaacgg ttgccttgag gaagaaataa tttggtttta 3750

 ttaagagtct actctcaatc cagttattag agatgtactg agtttgattt 3800

 gttaatcctt tctatatact gctgatcttg catgtctaca atctgctcag 3850

 tttttctgtg tttctgcaat agtggtcaga aaaatactta aattccctta 3900

 atggtgttgt tttctatttg ttctggtttt gagataaatg agtgattctg 3950

 tccccaaatg tccatttttg aagtgatttt cctggaggat tagggtattt 4000

 agcagttgaa gctcttcatt catagtagtt actgtcagct aacaggtttt 4050

 ttaaggcttt taactattaa tattttatgg aatggggcaa agtaaattga 4100

 tgaaagaatt ggagtgataa tagtccttta caaacataca gtccataaga 4150

 aaatgaattt ggcatataga attattacaa tttcctggga gagatggata 4200

 tttaaacctc tattatttta gacaagactg tctagaactt aagtttgatc 4250

 tgtcagccag tactcccatt aaattcagtg tagtttcact tgatagaatc 4300

 agatatgtta tcgaaatgtt agcagcagct tcatcctcct tctgattaaa 4350

 gtaagtagaa atgggatgtt ttgtttaata acagccatag tgtgtgttta 4400

 gaccacagcg gatgttgtag accaggacca tagatgatac atgtcagtgc 4450

 tgtggaatgt gcattctctg agtgttgttt tgtggtatca ttgtctttcc 4500

 tgaatgactt tctaactgtg cagaaaggca gaaaagtcat catatgtata 4550

 tgtcatatga ctttataaaa tatttaatgt gacaaaaagt ggaaagaatc 4600

 tttacaaacc ctgcaattac ttttttaaag gcacttttac tctttggttt 4650

 tatcattcca ttttgctaat atttactagc tttataaatt acagtaaggt 4700

 acaaaaactc atcttgtaat attttcattt ttgaagtgaa aaagtacata 4750

 tattttgcac aaggttttat actgctaagt gcttggttgg ggtggtgaga 4800

 tgatgattag atcaggggtg aggctgagag actctgggtt tagggctagc 4850

 cctgcctcca tctcccttgg gtaaaatgaa gggtgtgggg taaaagatgc 4900

 ataaggcctt ttctagctct gacagcctag aagtccaatc accctgtaat 4950

 aaatatgtgt tgaatgaaga aatgggtgaa tgagcttgtc aatgtgattt 5000

 taaaaaattg actacctgga ggaatgatta ggaatctaaa tgaagccagc 5050

 cctcggtatc tgcaggtttc tcatccatgg attcaaccaa ctgcaaatgg 5100

 aaaatacgat tttttttaaa aaaaggatgg ttacatccgt attgaacatg 5150

 tacagacttt tttcttgtca ttattctctg aacaatacaa gaactcttta 5200

 tgtagcattt acatttatta ggtattataa gtaatctaga gattatttaa 5250

 ttaaaatata caggaggatg tgtgtcagtt atatgcaaat tctgtaccat 5300

 tttgtatcag ggaattgagc atcttcagat gttggtatct gcagggatcc 5350

 tggaaccaaa cccctgcaga tactaagggc tgacgatcta ggtaagactg 5400

 gatttaacag ttgg 5414

<210> 3673
<211> 926
<212> DNA
<213> Homo sapien

<400> 3673
 ctgaattacg aaggcagtcc aattaaagta acactggcaa ctttgaaaat 50

 gtctgtacag ccaacggttt cccttggggg ctttgaaata acaccaccag 100

 tggtcttaag gttgaagtgt ggttcagggc cagtgcatat tagtggacag 150

 cacttagtag ctgtggagga agatgcagag tcagaagatg aagaggagga 200

 ggatgtgaaa ctcttaagta tatctggaaa gcggtctgcc cctggaggtg 250

 gtagcaaggt tccacagaaa aaagtaaaac ttgctgctga tgaagatgat 300

 gacgatgatg atgaagagga tgatgatgaa gatgatgatg atgatgattt 350

 tgatgatgag gaagctgaag aaaaagcgcc agtgaagaaa tctatacgag 400

 atactccagc caaaaatgca caaaagtcaa atcagaatgg aaaagactca 450

 aaaccatcat caacaccaag atcaaaagga caagaatcct tcaagaaaca 500

 ggaaaaaact cctaaaacac caaaaggacc tagttctgta gaagacatta 550

 aagcaaaaat gcaagcaagt atagaaaaag cgcattgaac agtcctgggc 600

 actacatgta aattaagccc aaagatgggg agaaaggaaa aggagagaca 650

 aatatagtcc atactgagtg tcatcaacaa tccagactga agtcttctat 700

 tttaatctca atcccctttt ctgatttgcc acccatgcct cttcaggctg 750

 gaaacaatct cttggttccc taaagcactt tcttctgact gctgtgattc 800

 agtgaacctt gccctttgct ttctattact tgtgcatttg cctcacctga 850

 caatgtttta aatcgccttt gtatctcctt agctgctcaa taaatatttg 900

 aatgcatcaa aaaaaaaaaa aaaaaa 926

<210> 3674
<211> 179
<212> PRT
<213> Homo sapien

<400> 3674
 Met Ser Val Gln Pro Thr Val Ser Leu Gly Gly Phe Glu Ile Thr
   1               5                  10                  15

 Pro Pro Val Val Leu Arg Leu Lys Cys Gly Ser Gly Pro Val His
                  20                  25                  30

 Ile Ser Gly Gln His Leu Val Ala Val Glu Glu Asp Ala Glu Ser
                  35                  40                  45

 Glu Asp Glu Glu Glu Glu Asp Val Lys Leu Leu Ser Ile Ser Gly
                  50                  55                  60

 Lys Arg Ser Ala Pro Gly Gly Gly Ser Lys Val Pro Gln Lys Lys
                  65                  70                  75

 Val Lys Leu Ala Ala Asp Glu Asp Asp Asp Asp Asp Asp Glu Glu
                  80                  85                  90

 Asp Asp Asp Glu Asp Asp Asp Asp Asp Asp Phe Asp Asp Glu Glu
                  95                 100                 105

 Ala Glu Glu Lys Ala Pro Val Lys Lys Ser Ile Arg Asp Thr Pro
                 110                 115                 120

 Ala Lys Asn Ala Gln Lys Ser Asn Gln Asn Gly Lys Asp Ser Lys
                 125                 130                 135

 Pro Ser Ser Thr Pro Arg Ser Lys Gly Gln Glu Ser Phe Lys Lys
                 140                 145                 150

 Gln Glu Lys Thr Pro Lys Thr Pro Lys Gly Pro Ser Ser Val Glu
                 155                 160                 165

 Asp Ile Lys Ala Lys Met Gln Ala Ser Ile Glu Lys Ala His
                 170                 175

<210> 3675
<211> 3492
<212> DNA
<213> Homo sapien

<400> 3675
 aagccgtgcg ctcccgggct gcgaggtctg gctaggctac gggccacgcg 50

 ccgccgccgc tgccgccgcc actgtcctct tcggaggcgc gggcccgacg 100

 gaaaccatgt ttgtggctcg cagcatcgcg gcggaccaca aggatctcat 150

 ccacgatgtc tctttcgact tccacgggcg gcggatggca acctgctcca 200

 gcgatcagag cgttaaggtc tgggataaaa gtgaaagtgg tgattggcat 250

 tgtacagcta gctggaagac acatagtgga tctgtatggc gtgtgacatg 300

 ggcccatcct gaatttgggc aagttttggc ttcctgttct tttgaccgaa 350

 cagctgctgt atgggaagaa atagtaggag aatcaaatga taaactgcga 400

 ggacagagcc actgggttaa aaggacaact ctggtggata gcagaacatc 450

 tgttactgat gtgaagtttg ctcccaagca catgggtctt atgttagcaa 500

 cctgttccgc agatggtata gtaagaatct atgaggcacc agatgttatg 550

 aatctcagcc agtggtcttt gcagcatgag atctcatgta agctaagctg 600

 tagttgcatt tcttggaacc cttcaagctc tcgtgctcat tcccccatga 650

 tcgccgtagg aagtgatgac agtagcccca acgcaatggc caaggttcag 700

 atttttgaat ataatgaaaa caccaggaaa tatgcaaaag ctgaaactct 750

 tatgacagtc actgatcctg ttcatgatat tgcattcgct ccaaatttgg 800

 gaagatcttt ccatattcta gcaatagcga ccaaagatgt gagaattttt 850

 acattaaagc ctgtgaggaa agaactgact tcctctggtg ggccaacaaa 900

 gtttgaaatc catatagtgg ctcagttcga taatcataat tctcaggtct 950

 ggcgagtgag ttggaatata acaggaacgg tgctagcatc ttcaggagat 1000

 gatgggtgtg taagattgtg gaaagctaat tatatggaca attggaagtg 1050

 tactggtatt ttgaaaggta atgggagccc agtcaatggg agttctcagc 1100

 agggaacctc aaatccttcc ctaggttcaa atattccaag tcttcagaat 1150

 tcattaaatg gatcttctgc tggcagaaag cacagctgag acaagctaac 1200

 tggagtaact ttgctgtttt gctgcttgtt gcatgcacac tggaatggaa 1250

 agcgagctcc cttttcccct tccccagcgc cgtttgacct ctcccaagga 1300

 tacaccagca gcctgcttac tactaaacgc aatccaaaag gcctttaaaa 1350

 atacagtgta tattttttgt actagtcagt ttattgacac tatttgaaac 1400

 ttttgaaata taaacggaga ggctttctgt tgagacattg tcaccaaaac 1450

 aattttttga aatgttcctg aaactaattt gggtttaaag attaaaaggg 1500

 ttgttaccat tcttatctga gtagttggga ggaggggaat accactttag 1550

 ttcatttgga aaatatagac atatttcttt tgctttctta aaacagctta 1600

 aaatgatgaa cttttataat tttaatttga agattgaata aatatttttt 1650

 ataaagattg ttttgagtgc tgatttgttt actttttgta gatttgcttt 1700

 atccatgata ttcagtacaa ctctgtcatt tctttgtaat atttaaaaaa 1750

 tattagtaaa ggagtgaatt aataaagtag taatagtaaa atgaaaggaa 1800

 cttgactgta cagtttgtag cccaggttaa ggcatttggg tattgtttca 1850

 tttaaccaat ttggggacta agatgggaaa cacttttttt attaagtttt 1900

 taattcatag tcactaaaga gataaatgtt tcttatatac atttgtgtat 1950

 ttttatggtg ttatttattc catggcttag cttccttcaa atcaaaattt 2000

 ggacacacac tattaagaga agccattaaa attttactaa aattgtgcat 2050

 gtaaattaat tgtcagcatt ccatgtctca agattttctt aatttagttc 2100

 gctgtttaaa ttaattcatg tcctgtaaag ttctgacctt gataacaaag 2150

 ctataaatat ttaagtttgc taatatgcgt aagtattatc ggtaagttac 2200

 aagatggaag aagaataaca gtagggcaca gtcattctgt gaatcctttt 2250

 acttatcaaa atttggtagc tattctaagg cttttgcaga aaaataagtg 2300

 ttcaatgttt gtagttcttc aaaagcatgt tgcagtagcc agccatacta 2350

 tgtgtattcc cagtatcatg tacgcactaa aaaaaatgtg tgcttgctgc 2400

 tgctgtgagt gaaccattgc ttaagataaa aaacttaact agatctgtaa 2450

 atgtacagaa tagcatcaga tgtttctgag agattaggaa aatgttttga 2500

 atttataaaa ttaatgtttt tctttgtaac atttatatat attttttaac 2550

 attttaagtt taacagattg tattcctttc aagtttctat acttgcttaa 2600

 gcaatcttga tttgagtaag ggtcttgatt tgtgctatta tgttctgtta 2650

 gttttggcat gaatatacta aagctttttt tttttttttt agcatgtgtt 2700

 ttctcctctt tggttctctt tgtatttact acttttctct ttttcttgtg 2750

 tttttttttt cctgtttttg ttttgtttgg tgttttgttc ctgtcttcat 2800

 tgtttcaggt atttctttac ccctctggat tccccacggg ctggatcgag 2850

 atggtccagt tatgcccagc tccttcctcc tcctcctcct cctctggtag 2900

 agcactcttg cgatgctgac actgccaacc tccagtatcc tcaccctcgc 2950

 agacgatatc tctctcggcc tcttaatccc ttacctgaga atgaagggat 3000

 ttaaaacact gatttaacat tgaaaggcct tattcaagtg cttgtaaatg 3050

 ctttcatttc tggctgcttt ttgtttttca ttttctttca gaagattttt 3100

 ctaacttagg gtctgtcttg catgtattac aaccagaata cagtgtttgg 3150

 aacctaaatc tgtttgtgcg tctgcatcaa aggaacattt gcttcactgg 3200

 gtgataacct ttgatgaaat gagatatgtc caagtaacgt taactgtgaa 3250

 gttacacaca gtagctgact tcaaagtgcc tgttcctgta aattttattt 3300

 taaactgtta ccatagtctt aagttgttta tgctttatca gactggctaa 3350

 tgtgaaagca taatattatg aagtttattc tgccttatga gaccttaaaa 3400

 aatggatttc attttacagg ctaatgttgt aactgactag tatgtaaaat 3450

 aaatcattcc tgtgtataaa gcagcaaaac ctaaaaaaaa aa 3492

<210> 3676
<211> 360
<212> PRT
<213> Homo sapien

<400> 3676
 Met Phe Val Ala Arg Ser Ile Ala Ala Asp His Lys Asp Leu Ile
   1               5                  10                  15

 His Asp Val Ser Phe Asp Phe His Gly Arg Arg Met Ala Thr Cys
                  20                  25                  30

 Ser Ser Asp Gln Ser Val Lys Val Trp Asp Lys Ser Glu Ser Gly
                  35                  40                  45

 Asp Trp His Cys Thr Ala Ser Trp Lys Thr His Ser Gly Ser Val
                  50                  55                  60

 Trp Arg Val Thr Trp Ala His Pro Glu Phe Gly Gln Val Leu Ala
                  65                  70                  75

 Ser Cys Ser Phe Asp Arg Thr Ala Ala Val Trp Glu Glu Ile Val
                  80                  85                  90

 Gly Glu Ser Asn Asp Lys Leu Arg Gly Gln Ser His Trp Val Lys
                  95                 100                 105

 Arg Thr Thr Leu Val Asp Ser Arg Thr Ser Val Thr Asp Val Lys
                 110                 115                 120

 Phe Ala Pro Lys His Met Gly Leu Met Leu Ala Thr Cys Ser Ala
                 125                 130                 135

 Asp Gly Ile Val Arg Ile Tyr Glu Ala Pro Asp Val Met Asn Leu
                 140                 145                 150

 Ser Gln Trp Ser Leu Gln His Glu Ile Ser Cys Lys Leu Ser Cys
                 155                 160                 165

 Ser Cys Ile Ser Trp Asn Pro Ser Ser Ser Arg Ala His Ser Pro
                 170                 175                 180

 Met Ile Ala Val Gly Ser Asp Asp Ser Ser Pro Asn Ala Met Ala
                 185                 190                 195

 Lys Val Gln Ile Phe Glu Tyr Asn Glu Asn Thr Arg Lys Tyr Ala
                 200                 205                 210

 Lys Ala Glu Thr Leu Met Thr Val Thr Asp Pro Val His Asp Ile
                 215                 220                 225

 Ala Phe Ala Pro Asn Leu Gly Arg Ser Phe His Ile Leu Ala Ile
                 230                 235                 240

 Ala Thr Lys Asp Val Arg Ile Phe Thr Leu Lys Pro Val Arg Lys
                 245                 250                 255

 Glu Leu Thr Ser Ser Gly Gly Pro Thr Lys Phe Glu Ile His Ile
                 260                 265                 270

 Val Ala Gln Phe Asp Asn His Asn Ser Gln Val Trp Arg Val Ser
                 275                 280                 285

 Trp Asn Ile Thr Gly Thr Val Leu Ala Ser Ser Gly Asp Asp Gly
                 290                 295                 300

 Cys Val Arg Leu Trp Lys Ala Asn Tyr Met Asp Asn Trp Lys Cys
                 305                 310                 315

 Thr Gly Ile Leu Lys Gly Asn Gly Ser Pro Val Asn Gly Ser Ser
                 320                 325                 330

 Gln Gln Gly Thr Ser Asn Pro Ser Leu Gly Ser Asn Ile Pro Ser
                 335                 340                 345

 Leu Gln Asn Ser Leu Asn Gly Ser Ser Ala Gly Arg Lys His Ser
                 350                 355                 360

<210> 3677
<211> 4559
<212> DNA
<213> Homo sapien

<400> 3677
 ggaagagaaa tcccaaagct tttgcaattc agtctgctgt ggggatggct 50

 tgatcctttc acaggactca ggatttgaag acaaaaaagc atcatattcc 100

 agtggttgat cagactccac tagagccgcc accaatagtg atagtggtga 150

 cggggcctcc aaaagttgga aagagcactt tgatataatg cctcattggg 200

 aacttcaccc agcagaagtt gaccgagatc agaggccctg tgatgatcgt 250

 gtcaggtaaa aagctccgac tcaccattat tgaatgtggg tgtgacatta 300

 acatgatgat tgatctggct gaagtagcag atctggttgc caagctgttc 350

 tacctttctg gaatggtgca tggagaatat caagaccaag aaatccacaa 400

 tctgggccat tttattacag ttatgaagtt taggcctctc acatggcaga 450

 cgtctcatcc ttatatcctg gcagacaggt aaaaagtgat tgtaagcttt 500

 tatttcctag accatatatt tcaaagctaa aaaggctaga aaaagaacag 550

 tgataggatt tattttgtgc ctatttgaat agtgggggta gaagtgtagt 600

 tgatggaaaa tgtctactta tatcattgct caaagatgct gtgcctttgg 650

 gagtaaatta attatgagat gtttaggaaa atgggaggac ttggaagcat 700

 ttaaagctac aggatatggc cccatcctat gttcagcctc agttttcagt 750

 gatgctgcct tcgtgcccgg gtgcttgagt cctttatgtg tgccttcagt 800

 ttccttcctt tgtgctcttc tttgtgctgt ggttttctca gcctggaata 850

 ccctttttcc acctgccaga atccaagcca cagtacaaat cccagagcac 900

 aggctcaccc tcttccagaa agggattttc tgaatatgtt cttcactctt 950

 ccctgacccc aggtggacgt catctccctg tctggtgtct tacggaatga 1000

 atgtcacttt cagcctagag acacagttgt gtgcctgccc cttttcctct 1050

 ggtgggtggt gaatggtgct tccttatttc tgtattttct agttttctaa 1100

 acgacatgct tagtggacaa gagtgtgatg agtcattgac acatgaaagg 1150

 acgtatagga actttggcat tcatttctgc tgtatgattg agtttatttt 1200

 tctaggatgg aagatttgaa aaacccagag gatatctgaa caaaatgtga 1250

 ctggcaggtg tcactttatg gttatttaag aggagcacac ttgaaaaata 1300

 aaagccaaat tcacatgcca ggtattctct tgttgtagaa catactagaa 1350

 tcacacatag gattcttggg atggcttctt ttctcaggaa aactgaaaaa 1400

 tgaccaaaca agggaagatg gctttggtgg aggttttaaa agtaagccag 1450

 ctatgtgtag gcctgtaaag gtgttattga atcccctctt ctctgacctt 1500

 ttgtcttata gctagaggag cactgttcca gtgtggcaca atactcttct 1550

 ttatggtcat gggttaagcc cttggactgt gcatcgtttt ttttttgttt 1600

 tgttattggt gactgacccc atgagtcatg ctctttacaa agcatgcatt 1650

 tggatgtttc tttctttttt ttattattat actttaagtt ctagggtaca 1700

 tgtgcacaat gtgcaggttt gttacatatg tatacatgtg ccgtgttggt 1750

 gtgctgcacc tgtcaactcg agatttacat taaatatatc tcccagtgct 1800

 atccctcccc actcccccac cccacgacag gcgctggtgt gtgatgttcc 1850

 ccaaaaataa ataaattaat taattaaata atagaaattc tcggctgctt 1900

 tttatagctg tagaaaaaaa aatgaaatct tattttaaac ttttcttttt 1950

 tttttttttt tttgagacag agtctcactt tgtctcccgg cctggagtgc 2000

 agtggcgcga actcggctca ctgcaagctc cgcctcctgg gttcacccca 2050

 ttctcctgtt tcagcctccc gagtaactgg gactacaggg gcctgctacc 2100

 acgcccggct aattttttgt atttttagta gagatggggt ttcaccatgt 2150

 taaccaggat ggtctcgatc tcctgacctc gtgatccgcc cgcctccacc 2200

 tcccaaagtg ctaggattac aggtgtgagc caccacgccc ggcgaagctg 2250

 acttttccca ttatttttaa cggtaattca taaaatcctt gttaggtttg 2300

 atgacaggta ccatattaag ggcagcattt tataacccat atcttaaaca 2350

 tcatctctgg aagttgagag cctccaatgg gttttctata gagtgcacat 2400

 gataccacac tcaggcagtt catggagtgt aagacatatc ttagtgcttt 2450

 gtcatttgac attttaactg agaaaaaaat atactttgat aagtttgact 2500

 tacacttccc ttccccttca ggtatctact gagcgtttca gtcaacaata 2550

 cagctcgtgt tcgacaatat tccttgatgg cagcacagcc agccagcatt 2600

 atcttataat gacaataata tctgtgacct tggagataca tcatcatatc 2650

 acggaaagag atgcagatag atctttgacc atacttgatg aacagttata 2700

 ctcatttgcg ttttccaccg tgcacattac gaagaaaaga aatggaggtg 2750

 ggagtttaaa taactattcc tcctccattc cattgactcc cagcaccagc 2800

 caggaggacc tttatttcag tgttcctccc actgccaaca cacccacgcc 2850

 catttgcaag cagtccatgg gctggtccaa cctgtttaca tctgagaaag 2900

 ggagtgaccc agacaaaggg aggaaagccc tggagagtca cgctgacacc 2950

 atcgggagcg gcagagccat ccccattaaa cagggcatgc tcttaaagcg 3000

 aagtgggaaa tggctgaaga catggaaaaa gaaatatgtc accctgtgtt 3050

 ccaatggcgt gctcacctat tattcaagct taggtgatta tatgaagaat 3100

 attcataaaa aagagattga ccttcggaca tctaccatca aagtcccagg 3150

 aaagtggcca tccctagcca catcggcctg cgcacccatc tccagctcta 3200

 aaagcaatgg cctatccaag gacatggaag ctctgcatat gtcagccaat 3250

 tcagacatcg ggctgggtga ctccatatgc ttcagcccca gtatctccag 3300

 caccaccagc cccaagctca acctgccccc ctcccctcat gccaataaaa 3350

 agaaacacct aaagaagaaa agcaccaaca acttaaaaga tgatggcctg 3400

 tccagcactg ctgaggaaga agaagaaaag tttatgattg tgtccgtcac 3450

 tggccaaacg tgccacttta aagccacgac gtatgaggag cgggatgcct 3500

 gggtccaagc catccagagc cagatcctgg ccagcctgca gtcatgcgag 3550

 agcagtaaaa gcaagtccca gctgaccagc cagagtgagg ccatggccct 3600

 gcagtcgatc caaaacatgc gtgggaactc ccactgcgtg gactgtgaga 3650

 cccagaatcc taagtgggcc agtttgaact tgggagtcct catgtgtatt 3700

 gaatgttcag gaatccaccg cagtcttggc acccgccttt cccgtgtgcg 3750

 atctctggag ctggatgact ggccagttga gctcaggaag gttatgtcat 3800

 ctattggcaa tgacctagcc aacagcatct gggaagggag cagccagggg 3850

 cagacgaaac cctcaataga gtcaacgagg gaagagaagg aacggtggat 3900

 ccgttccaaa tatgagcata agctctttct ggccccacta ccctgcactg 3950

 agctgtccct gggccagcac ctgctgcggg ccaccgctga tgaggacctg 4000

 cggacagcca tcctgctgct ggcacatggc tcccgtgagg aggtgaacga 4050

 gacctgtggg gagggagacg gctgcacggc gctccatctg gcctgccgca 4100

 aggggaatgt ggtcctggcg cagctcctga tctggtacgg ggtggacgtc 4150

 atggcccgag atgcccacgg gaacacagcg ctgacctacg cccggcaggc 4200

 ctccagccag gagtgcatca acgtgcttct gcagtacggc tgccccgacg 4250

 agtgcgtgta gtatctgttt tatttgactg cagtctcctt ggtgtaaaaa 4300

 caaaatggga aaaataagga taactcagaa tttcaaaagg aaatcacaaa 4350

 ttcagctaat aatagcattt tcagtacttt tcgtaaacta agtaaataca 4400

 caaaatgttg atttttctga ccataagaca tattttatgt ccttttgccg 4450

 aggtgggtgt gttagtctca ggccctcctg gccacattgc ccaagtcaca 4500

 caggcttctg tattatgtat ttagataaga tgtgtgaaaa tatatttgaa 4550

 aaaaagttc 4559

<210> 3678
<211> 597
<212> PRT
<213> Homo sapien

<400> 3678
 Leu Arg Lys Lys Tyr Thr Leu Ile Ser Leu Thr Tyr Thr Ser Leu
   1               5                  10                  15

 Pro Leu Gln Val Ser Thr Glu Arg Phe Ser Gln Gln Tyr Ser Ser
                  20                  25                  30

 Cys Ser Thr Ile Phe Leu Asp Gly Ser Thr Ala Ser Gln His Tyr
                  35                  40                  45

 Leu Ile Met Thr Ile Ile Ser Val Thr Leu Glu Ile His His His
                  50                  55                  60

 Ile Thr Glu Arg Asp Ala Asp Arg Ser Leu Thr Ile Leu Asp Glu
                  65                  70                  75

 Gln Leu Tyr Ser Phe Ala Phe Ser Thr Val His Ile Thr Lys Lys
                  80                  85                  90

 Arg Asn Gly Gly Gly Ser Leu Asn Asn Tyr Ser Ser Ser Ile Pro
                  95                 100                 105

 Leu Thr Pro Ser Thr Ser Gln Glu Asp Leu Tyr Phe Ser Val Pro
                 110                 115                 120

 Pro Thr Ala Asn Thr Pro Thr Pro Ile Cys Lys Gln Ser Met Gly
                 125                 130                 135

 Trp Ser Asn Leu Phe Thr Ser Glu Lys Gly Ser Asp Pro Asp Lys
                 140                 145                 150

 Gly Arg Lys Ala Leu Glu Ser His Ala Asp Thr Ile Gly Ser Gly
                 155                 160                 165

 Arg Ala Ile Pro Ile Lys Gln Gly Met Leu Leu Lys Arg Ser Gly
                 170                 175                 180

 Lys Trp Leu Lys Thr Trp Lys Lys Lys Tyr Val Thr Leu Cys Ser
                 185                 190                 195

 Asn Gly Val Leu Thr Tyr Tyr Ser Ser Leu Gly Asp Tyr Met Lys
                 200                 205                 210

 Asn Ile His Lys Lys Glu Ile Asp Leu Arg Thr Ser Thr Ile Lys
                 215                 220                 225

 Val Pro Gly Lys Trp Pro Ser Leu Ala Thr Ser Ala Cys Ala Pro
                 230                 235                 240

 Ile Ser Ser Ser Lys Ser Asn Gly Leu Ser Lys Asp Met Glu Ala
                 245                 250                 255

 Leu His Met Ser Ala Asn Ser Asp Ile Gly Leu Gly Asp Ser Ile
                 260                 265                 270

 Cys Phe Ser Pro Ser Ile Ser Ser Thr Thr Ser Pro Lys Leu Asn
                 275                 280                 285

 Leu Pro Pro Ser Pro His Ala Asn Lys Lys Lys His Leu Lys Lys
                 290                 295                 300

 Lys Ser Thr Asn Asn Leu Lys Asp Asp Gly Leu Ser Ser Thr Ala
                 305                 310                 315

 Glu Glu Glu Glu Glu Lys Phe Met Ile Val Ser Val Thr Gly Gln
                 320                 325                 330

 Thr Cys His Phe Lys Ala Thr Thr Tyr Glu Glu Arg Asp Ala Trp
                 335                 340                 345

 Val Gln Ala Ile Gln Ser Gln Ile Leu Ala Ser Leu Gln Ser Cys
                 350                 355                 360

 Glu Ser Ser Lys Ser Lys Ser Gln Leu Thr Ser Gln Ser Glu Ala
                 365                 370                 375

 Met Ala Leu Gln Ser Ile Gln Asn Met Arg Gly Asn Ser His Cys
                 380                 385                 390

 Val Asp Cys Glu Thr Gln Asn Pro Lys Trp Ala Ser Leu Asn Leu
                 395                 400                 405

 Gly Val Leu Met Cys Ile Glu Cys Ser Gly Ile His Arg Ser Leu
                 410                 415                 420

 Gly Thr Arg Leu Ser Arg Val Arg Ser Leu Glu Leu Asp Asp Trp
                 425                 430                 435

 Pro Val Glu Leu Arg Lys Val Met Ser Ser Ile Gly Asn Asp Leu
                 440                 445                 450

 Ala Asn Ser Ile Trp Glu Gly Ser Ser Gln Gly Gln Thr Lys Pro
                 455                 460                 465

 Ser Ile Glu Ser Thr Arg Glu Glu Lys Glu Arg Trp Ile Arg Ser
                 470                 475                 480

 Lys Tyr Glu His Lys Leu Phe Leu Ala Pro Leu Pro Cys Thr Glu
                 485                 490                 495

 Leu Ser Leu Gly Gln His Leu Leu Arg Ala Thr Ala Asp Glu Asp
                 500                 505                 510

 Leu Arg Thr Ala Ile Leu Leu Leu Ala His Gly Ser Arg Glu Glu
                 515                 520                 525

 Val Asn Glu Thr Cys Gly Glu Gly Asp Gly Cys Thr Ala Leu His
                 530                 535                 540

 Leu Ala Cys Arg Lys Gly Asn Val Val Leu Ala Gln Leu Leu Ile
                 545                 550                 555

 Trp Tyr Gly Val Asp Val Met Ala Arg Asp Ala His Gly Asn Thr
                 560                 565                 570

 Ala Leu Thr Tyr Ala Arg Gln Ala Ser Ser Gln Glu Cys Ile Asn
                 575                 580                 585

 Val Leu Leu Gln Tyr Gly Cys Pro Asp Glu Cys Val
                 590                 595

<210> 3679
<211> 958
<212> DNA
<213> Homo sapien

<400> 3679
 aagacagata aggaacaact agagggagaa gccaaggcag gcgtgtgtgg 50

 taacacatag gaactgaggg agaggacatt tcaagatggt ggggatgcca 100

 tacaacagga ctatgtgatg gtttttggct gtgtccatag gaagtcacaa 150

 caggcaaggg aaagaaacca gaacccagtc atggagttaa gaagtgagtc 200

 agagagtaga tgggtaggga cagtgaggta aggcctcttt ctaaggaagt 250

 ttggctgaag gatagactag ctggacacat gctggctgtg tggggtagag 300

 ggaggaatga tggagggtag gagagccttg agcctgcgag aagagtctct 350

 tagaatagag aagctgaagt taaagttgtg gaagagagtg gggataactg 400

 agtgacagat aatcaggaga agaaaaggag atccagactc atgacagaga 450

 gatgaccttt gccaagagca cagccgtctt tcacggtcac agagaggtag 500

 gacaaaatga gtggtgttca agaattggtt tgtagcacaa tatttcaact 550

 atgtccttta aaaagtttct ccacagacac tacccaaagc agtgcttcac 600

 tacagtggca gacagacctg aaaattttca tctgaagcag cagagtgaac 650

 tgcagaggca ggtcaccaac cagtgtggag gctaaaagcg ggcctctttg 700

 gggattccag gtggaagtgt tggacatctg tagtattcct ggtctcgaat 750

 catcctgata ttcttcattt tgttattcac attggactag gcaggaacaa 800

 agatcaccac aactggctcg ccttcaacta tgttagatgg caacttgcct 850

 tcagtatggt gaaacacatc agttaagacc ggggttgtgc atggcaggac 900

 tttctacaag gacacccagt ctccttaata aacatgagat gctctctttc 950

 ccgaaaaa 958

<210> 3680
<211> 19
<212> PRT
<213> Homo sapien

<400> 3680
 Lys Thr Asp Lys Glu Gln Leu Glu Gly Glu Ala Lys Ala Gly Val
   1               5                  10                  15

 Cys Gly Asn Thr


<210> 3681
<211> 1706
<212> DNA
<213> Homo sapien

<400> 3681
 gttgtgagct gcggcagaga ctggtggctg gaggagacgc cggcgctgga 50

 gagtgcgctg cgccgcccgc cgctgaggga ccgcggggtt agccactgct 100

 ggctgcttcc agtgttcgcc gagaggtacc gggggtgaca gctccgggac 150

 cggccgaaag gcgaggaacc ggtgtggaaa ttaaaagaac acacatattt 200

 tgactggggc tttgatcaac caaatgctaa aaagccacac aaagaagatc 250

 cctaatagtc atttctcaac aattatatag tcaactgatg taacaatggt 300

 actaatattg ggacgcagac taaacagaga ggatcttggg gtgcgtgatt 350

 ccccagcaac taagcgaaaa gtttttgaaa tggaccccaa atctctgaca 400

 ggtcatgagt tttttgactt ctcttcagga tcatcccatg ccgaaaacat 450

 actccagata tttaatgaat ttcgtgatag ccgcttattc acagatgtta 500

 tcatttgtgt ggaaggaaaa gaatttcctt gccatagagc tgtgctctca 550

 gcctgtagca gctacttcag agctatgttt tgtaatgacc acagggaaag 600

 ccgagaaatg ttggttgaga tcaatggtat tttagctgaa gctatggaat 650

 gttttttgca gtatgtttat actggaaagg tgaagatcac tacagagaat 700

 gtacagtatc tctttgagac atcaagcctc tttcagatta gtgttctccg 750

 tgatgcatgt gccaagttct tggaggagca acttgatcct tgtaattgct 800

 taggaatcca gcgctttgct gatacccatt cactcaaaac actcttcaca 850

 aaatgcaaaa attttgcgtt acagactttt gaggatgtat cccagcacga 900

 agaatttctt gagcttgaca aagatgaact ttatgttgtc ggtggctatg 950

 atgggcaaaa cagacttagc agcgtagaat gttatgattc cttttcaaat 1000

 cgatggactg aagttgctcc ccttaaggaa gccgtgagtt ctcctgcagt 1050

 gactagctgt gtaggcaaac tgtttgtgat tggtggagga cctgatgata 1100

 atacttgttc tgataaggtt caatcttatg atccagaaac caattcttgg 1150

 ctacttcgtg cagctatccc aattgccaaa aggtgtataa cagctgtatc 1200

 cctaaacaac ctgatctatg ttgccggtgg actgaccaag gcaatatgct 1250

 gttacgatcc agttgaagat tactggatgc acgtacagaa tacattcagc 1300

 cgtcaggaaa actgtggtat gtctgtgtgt aatggtaaaa tatatatcct 1350

 gggcggaaga cgggaaaatg gagaagccac agacactatt ctctgttatg 1400

 atcctgcaac aagtatcatc acaggggtag ctgcaatgcc caggccagtg 1450

 tcctatcatg gctgtgtgac tattcataga tacaatgaga aatgctttaa 1500

 actctgaaga caggatacct caccgaagaa gccacactga tccaagatgg 1550

 gaggttttaa aaactctaca gtgggaactt cacatatctc ctttgtgcca 1600

 tatgcaaaaa atagtaaaaa taataatttg gtgcctttct cctcaaaata 1650

 tcaatctttc aaactataat aaagcctttc ctataattga aaaaaaaaaa 1700

 aaaaaa 1706

<210> 3682
<211> 403
<212> PRT
<213> Homo sapien

<400> 3682
 Met Val Leu Ile Leu Gly Arg Arg Leu Asn Arg Glu Asp Leu Gly
   1               5                  10                  15

 Val Arg Asp Ser Pro Ala Thr Lys Arg Lys Val Phe Glu Met Asp
                  20                  25                  30

 Pro Lys Ser Leu Thr Gly His Glu Phe Phe Asp Phe Ser Ser Gly
                  35                  40                  45

 Ser Ser His Ala Glu Asn Ile Leu Gln Ile Phe Asn Glu Phe Arg
                  50                  55                  60

 Asp Ser Arg Leu Phe Thr Asp Val Ile Ile Cys Val Glu Gly Lys
                  65                  70                  75

 Glu Phe Pro Cys His Arg Ala Val Leu Ser Ala Cys Ser Ser Tyr
                  80                  85                  90

 Phe Arg Ala Met Phe Cys Asn Asp His Arg Glu Ser Arg Glu Met
                  95                 100                 105

 Leu Val Glu Ile Asn Gly Ile Leu Ala Glu Ala Met Glu Cys Phe
                 110                 115                 120

 Leu Gln Tyr Val Tyr Thr Gly Lys Val Lys Ile Thr Thr Glu Asn
                 125                 130                 135

 Val Gln Tyr Leu Phe Glu Thr Ser Ser Leu Phe Gln Ile Ser Val
                 140                 145                 150

 Leu Arg Asp Ala Cys Ala Lys Phe Leu Glu Glu Gln Leu Asp Pro
                 155                 160                 165

 Cys Asn Cys Leu Gly Ile Gln Arg Phe Ala Asp Thr His Ser Leu
                 170                 175                 180

 Lys Thr Leu Phe Thr Lys Cys Lys Asn Phe Ala Leu Gln Thr Phe
                 185                 190                 195

 Glu Asp Val Ser Gln His Glu Glu Phe Leu Glu Leu Asp Lys Asp
                 200                 205                 210

 Glu Leu Tyr Val Val Gly Gly Tyr Asp Gly Gln Asn Arg Leu Ser
                 215                 220                 225

 Ser Val Glu Cys Tyr Asp Ser Phe Ser Asn Arg Trp Thr Glu Val
                 230                 235                 240

 Ala Pro Leu Lys Glu Ala Val Ser Ser Pro Ala Val Thr Ser Cys
                 245                 250                 255

 Val Gly Lys Leu Phe Val Ile Gly Gly Gly Pro Asp Asp Asn Thr
                 260                 265                 270

 Cys Ser Asp Lys Val Gln Ser Tyr Asp Pro Glu Thr Asn Ser Trp
                 275                 280                 285

 Leu Leu Arg Ala Ala Ile Pro Ile Ala Lys Arg Cys Ile Thr Ala
                 290                 295                 300

 Val Ser Leu Asn Asn Leu Ile Tyr Val Ala Gly Gly Leu Thr Lys
                 305                 310                 315

 Ala Ile Cys Cys Tyr Asp Pro Val Glu Asp Tyr Trp Met His Val
                 320                 325                 330

 Gln Asn Thr Phe Ser Arg Gln Glu Asn Cys Gly Met Ser Val Cys
                 335                 340                 345

 Asn Gly Lys Ile Tyr Ile Leu Gly Gly Arg Arg Glu Asn Gly Glu
                 350                 355                 360

 Ala Thr Asp Thr Ile Leu Cys Tyr Asp Pro Ala Thr Ser Ile Ile
                 365                 370                 375

 Thr Gly Val Ala Ala Met Pro Arg Pro Val Ser Tyr His Gly Cys
                 380                 385                 390

 Val Thr Ile His Arg Tyr Asn Glu Lys Cys Phe Lys Leu
                 395                 400

<210> 3683
<211> 2477
<212> DNA
<213> Homo sapien

<400> 3683
 gcagaggtgc ggccggggag gcgcgcggag gctggagctg gaggcgcggc 50

 gccggtgagc tgagaaccat gtgtgctcag tattgcatct cctttgctga 100

 tgttgaaaaa gctcatatca acattcgaga ttctatccac ctcacaccag 150

 tgctaacaag ctccattttg aatcaactaa cagggcgcaa tcttttcttc 200

 aaatgtgaac tcttccagaa aacaggatct tttaagattc gtggtgctct 250

 caatgccgtc agaagcttgg ttcctgatgc tttagaaagg aagccgaaag 300

 ctgttgttac tcacagcagt ggaaaccatg gccaggctct cacctatgct 350

 gccaaattgg aaggaattcc tgcttatatt gtggtgcccc agacagctcc 400

 agactgtaaa aaacttgcaa tacaagccta cggagcgtca attgtatact 450

 gtgaacctag tgatgagtcc agagaaaatg ttgcaaaaag agttacagaa 500

 gaaacagaag gcatcatggt acatcccaac caggagcctg cagtgatagc 550

 tggacaaggg acaattgccc tggaagtgct gaaccaggtt cctttggtgg 600

 atgcactggt ggtacctgta ggtggaggag gaatgcttgc tggaatagca 650

 attacagtta aggctctgaa acctagtgtg aaggtatatg ctgctgaacc 700

 ctcaaatgca gatgactgct accagtccaa gctgaagggg aaactgatgc 750

 ccaatcttta tcctccagaa accatagcag atggtgtcaa atccagcatt 800

 ggcttgaaca cctggcctat tatcagggac cttgtggatg atatcttcac 850

 tgtcacagag gatgaaatta agtgtgcaac ccagctggtg tgggagagga 900

 tgaaactact cattgaacct acagctggtg ttggagtggc tgctgtgctg 950

 tctcaacatt ttcaaactgt ttccccagaa gtaaagaaca tttgtattgt 1000

 gctcagtggt ggaaatgtag acttaacctc ctccataact tgggtgaagc 1050

 aggctgaaag gccagcttct tatcagtctg tttctgttta atttacagaa 1100

 aaggaaatgg tgggaattca gtgtctttag atactgaaga cattttgttt 1150

 cctagtattg tcaactctta gttatcagat tcttaatgga gagtggctat 1200

 ttcattaaga tttaatagtt ttttttggac taagtagtgg aaaaactttt 1250

 atacttaact gagacatttt gtcaaggcta aaaaaaagtc ttgcaaaatg 1300

 gggcagtgga ctgacaggct gacatagaaa ataaactttg cccaatcaca 1350

 acttgtgcct cccatccctg gagtactgac tggcaccggt aagacagaat 1400

 ctctctgaat ccattactcc atgccccctt gaggcactgt tgaagaaatc 1450

 tcacttttca gccagggtac tggttctggt acatatggat cataagtcca 1500

 tttggggaag actcgtttat acaggttcat cagtactgtg tcttgagatt 1550

 ttagcttccc atcaaagctg catttcatgt ggccatgggt acctagaaag 1600

 acatcagaac aagtcggtca aattaaaagt agaaaatttt aaagcaatga 1650

 cttccaaccc aacagtcatt tagcaacact gcagaaatgc agacatggtc 1700

 tcaaatcccg tgtttcctta cctaaaggtt ccttgatatg tcctctccgg 1750

 ccccacttcg ttctcagttc cactggttta aaccacagca catcctctta 1800

 gaatcaaaca cattaaagac caagatgaaa catttaccca caaaatgtaa 1850

 acccaacctt tataccacaa aggcaatcag atcccatcct cctccttcat 1900

 acccacctct gttgaagaac atgtaacgta ctactgccat cttagtaaaa 1950

 attttgaaag gatgaccact cagaacaact ctcttgatga ccattctgtc 2000

 tggatctact gacataagat ggcctgtagc aatgaggctg tgcattccta 2050

 aaggacaaaa gcaaagaagc tatttaggaa tttacaggcc aaagtcttca 2100

 tttattgccc agtccattta aagacccatg caagagcctg gtttgtcatc 2150

 cctgccctag cccaatctga ggctaagatt ggtaaactgt aagcccacac 2200

 ttaaccttgt caataggttc ttgaaaactt gtacttcaag agaaatgatg 2250

 tataacaaaa ccatactttt tctcatcagt tgttacaagg aaaggatgtt 2300

 gaacaaaagg cagttatttg aggactggct atacactgtt tcacgtaaaa 2350

 gttggagttt tcattgttct attaacaatg ttaaatgaag acttactgta 2400

 ttttgaaaac catcattacc ttctccatac catttggctc ccaaatttaa 2450

 ataaacaaga gaaaacggtg ttcatct 2477

<210> 3684
<211> 340
<212> PRT
<213> Homo sapien

<400> 3684
 Met Cys Ala Gln Tyr Cys Ile Ser Phe Ala Asp Val Glu Lys Ala
   1               5                  10                  15

 His Ile Asn Ile Arg Asp Ser Ile His Leu Thr Pro Val Leu Thr
                  20                  25                  30

 Ser Ser Ile Leu Asn Gln Leu Thr Gly Arg Asn Leu Phe Phe Lys
                  35                  40                  45

 Cys Glu Leu Phe Gln Lys Thr Gly Ser Phe Lys Ile Arg Gly Ala
                  50                  55                  60

 Leu Asn Ala Val Arg Ser Leu Val Pro Asp Ala Leu Glu Arg Lys
                  65                  70                  75

 Pro Lys Ala Val Val Thr His Ser Ser Gly Asn His Gly Gln Ala
                  80                  85                  90

 Leu Thr Tyr Ala Ala Lys Leu Glu Gly Ile Pro Ala Tyr Ile Val
                  95                 100                 105

 Val Pro Gln Thr Ala Pro Asp Cys Lys Lys Leu Ala Ile Gln Ala
                 110                 115                 120

 Tyr Gly Ala Ser Ile Val Tyr Cys Glu Pro Ser Asp Glu Ser Arg
                 125                 130                 135

 Glu Asn Val Ala Lys Arg Val Thr Glu Glu Thr Glu Gly Ile Met
                 140                 145                 150

 Val His Pro Asn Gln Glu Pro Ala Val Ile Ala Gly Gln Gly Thr
                 155                 160                 165

 Ile Ala Leu Glu Val Leu Asn Gln Val Pro Leu Val Asp Ala Leu
                 170                 175                 180

 Val Val Pro Val Gly Gly Gly Gly Met Leu Ala Gly Ile Ala Ile
                 185                 190                 195

 Thr Val Lys Ala Leu Lys Pro Ser Val Lys Val Tyr Ala Ala Glu
                 200                 205                 210

 Pro Ser Asn Ala Asp Asp Cys Tyr Gln Ser Lys Leu Lys Gly Lys
                 215                 220                 225

 Leu Met Pro Asn Leu Tyr Pro Pro Glu Thr Ile Ala Asp Gly Val
                 230                 235                 240

 Lys Ser Ser Ile Gly Leu Asn Thr Trp Pro Ile Ile Arg Asp Leu
                 245                 250                 255

 Val Asp Asp Ile Phe Thr Val Thr Glu Asp Glu Ile Lys Cys Ala
                 260                 265                 270

 Thr Gln Leu Val Trp Glu Arg Met Lys Leu Leu Ile Glu Pro Thr
                 275                 280                 285

 Ala Gly Val Gly Val Ala Ala Val Leu Ser Gln His Phe Gln Thr
                 290                 295                 300

 Val Ser Pro Glu Val Lys Asn Ile Cys Ile Val Leu Ser Gly Gly
                 305                 310                 315

 Asn Val Asp Leu Thr Ser Ser Ile Thr Trp Val Lys Gln Ala Glu
                 320                 325                 330

 Arg Pro Ala Ser Tyr Gln Ser Val Ser Val
                 335                 340

<210> 3685
<211> 2275
<212> DNA
<213> Homo sapien

<400> 3685
 gcgcagttgt cgtctcttgc ggtgccgttg ctggttctca caccttttag 50

 gtctgttctc gtcttccgtt ccgactctct ctttttcgtt gcagccactg 100

 aagatcctgg tgtcgccatg ggccgccgcc ccgcccgttg gtgagtcttg 150

 aatccgtgta ctttcactgc tgggaaacgg gcggggaaag aagtgcctat 200

 ggccgctgaa aacaattgtg gggtggagcc tcccccgtgc ggcggccctg 250

 tcttgggaac tgaccctatg ttttacacct cccggctatt ttttagtctg 300

 caatattact gtctgttcct tcgttcccgt gtcggtgtgg aagcgacggt 350

 tccctcgtat ctctgcctgt gtcctgcaag ctcaccgcat tttcgggcgc 400

 tagatacgct cttggggcct ttgtgtgcgt tctctgtctt atttccgggc 450

 gacgtgccgc gtgcgttgtc ggacgtgaag ggcagtccgg gaaaaacggg 500

 tgcggccgcc tcctgtgtcc tacagggggc gccagacgca tttccactcg 550

 gcttggaggt ggatttagtg ccacgtgccc gaaagtctta aattgggtga 600

 cctgagctgt gcaatgataa tgcggcgatt ttgtagtacg cagtgtcttg 650

 aagagagaat ttttaactag gaaagtttgt tgcaaagtgt ttataggaag 700

 cgtaagacaa agtaacggaa gatggtgtct gttgtttcta gtcttgggtg 750

 ttctctgtgt tgcagcagcc aactgttgct ttgtagttta tttccccgaa 800

 tggaaacggt ttagaagtgg acgtgcattc cccacccttt tcccgtccct 850

 cgtttgggtt gttccttgag gggcaaagtg cctgttgggc tttctgtgaa 900

 cctcacctaa cctgtgtttt ttcactcccc tgcagttacc ggtattgtaa 950

 gaacaagccg tacccaaagt ctcgcttctg ccgaggtgtc cctgatgcca 1000

 agattcgcat ttttgacctg gggcggaaaa aggcaaaagt ggatgagttt 1050

 ccgctttgtg gccacatggt gtcagatgaa tatgagcagc tgtcctctga 1100

 agccctggag gctgcccgaa tttgtgccaa taagtacatg gtaaaaagtt 1150

 gtggcaaaga tggcttccat atccgggtgc ggctccaccc cttccacgtc 1200

 atccgcatca acaagatgtt gtcctgtgct ggggctgaca ggtgagcttg 1250

 gtctgggcct tttaaggcag ttggagtctc tacattatta ggcttgcatt 1300

 attttatcag agcatagagg tggccccagt gactcagcca ctatggctac 1350

 tagaaaagcc aggctggcaa gtgactttca gtggtcactc aggacccctt 1400

 cctgcagata caaacaaagc atgagtaagt cttagcaagc tcttccccac 1450

 aggttagggg aaacactggt gatgggagta gctcttcttg cttttagctg 1500

 aatgacaacc atcttgccag caggtagctg aagctggcag aggagcccag 1550

 tggcgccttt tcagtggttc ttgggatgct ccgcagccaa ttaagccgac 1600

 tgagttcctt tcctcatggg gacccagtgt gcgatggctg cacacagcag 1650

 cttccttggt agtgtacgca gcctgttggt tgtatgggtt gctctaaggg 1700

 accttggaga caggcctttc aggtggatgt tcatgtttct gaccttgcac 1750

 taccccaatg taggctccaa acaggcatgc gaggtgcctt tggaaagccc 1800

 cagggcactg tggccagggt tcacattggc caagttatca tgtccatccg 1850

 caccaagctg cagaacaagg agcatgtgat tgaggccctg cgcagggcca 1900

 agttcaagtt tcctggccgc cagaaggtat gtagtgctgc agcccccttc 1950

 tcccaccttt gccccaggcc tcctgactca gttctttcca ttgctcctta 2000

 gatccacatc tcaaagaagt ggggcttcac caagttcaat gctgatgaat 2050

 ttgaagacat ggtggctgaa aagcggctca tcccagatgg ctgtggggtc 2100

 aagtacatcc ccagtcgtgg ccctctggac aagtggcggg ccctgcactc 2150

 atgagggctt ccaatgtgct gcccccctct taatactcac caataaattc 2200

 tacttcctgt ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2250

 aaaaaaaaaa aaaaaaaaaa aaaaa 2275

<210> 3686
<211> 130
<212> PRT
<213> Homo sapien

<400> 3686
 Met Ala Ala Glu Asn Asn Cys Gly Val Glu Pro Pro Pro Cys Gly
   1               5                  10                  15

 Gly Pro Val Leu Gly Thr Asp Pro Met Phe Tyr Thr Ser Arg Leu
                  20                  25                  30

 Phe Phe Ser Leu Gln Tyr Tyr Cys Leu Phe Leu Arg Ser Arg Val
                  35                  40                  45

 Gly Val Glu Ala Thr Val Pro Ser Tyr Leu Cys Leu Cys Pro Ala
                  50                  55                  60

 Ser Ser Pro His Phe Arg Ala Leu Asp Thr Leu Leu Gly Pro Leu
                  65                  70                  75

 Cys Ala Phe Ser Val Leu Phe Pro Gly Asp Val Pro Arg Ala Leu
                  80                  85                  90

 Ser Asp Val Lys Gly Ser Pro Gly Lys Thr Gly Ala Ala Ala Ser
                  95                 100                 105

 Cys Val Leu Gln Gly Ala Pro Asp Ala Phe Pro Leu Gly Leu Glu
                 110                 115                 120

 Val Asp Leu Val Pro Arg Ala Arg Lys Ser
                 125                 130

<210> 3687
<211> 789
<212> DNA
<213> Homo sapien

<400> 3687
 tccacacgga tcacttccga aacacttggc ttcagcccct gcctcggcca 50

 gaggtttcat ttttaactga atatttacga aagctgaaag cgtgcgaggg 100

 gggtggggtg gaaatagcgg ctgcttcttt tccaaggatt tatttaatgg 150

 ggatgtgttc aaggcaagac cgaattcaga aggatatcga cgtcgtgatc 200

 cagaagtcca gagctgagga ctgcctgttt gcagggcccg cctggcagga 250

 cgactgagca agtccttgga aaaccagaga tattagagcg gtgaatcgcg 300

 ctggtcacgt tggacacctg cgcgttagga gattctggag ccagagggag 350

 agaccccaga aactccccgg tcggcgaccc agcccgagac gcctggggtc 400

 ccaagggaag ctgaacgccc gcagaatggg gaaatggaga gagaacctga 450

 aagagcccca aactcgagga cctattgctc cccaagaata acatcttcca 500

 gaactagaca gaaaactagg cgtctgggaa ccctgaaatc cttggaggag 550

 tagatcatca tgaccctctg tgttcctttt ggcaaatgac ttgcttccat 600

 tgtttgttca attgtctgtt tgttaaataa ataaaaccct ttttatgtat 650

 ctttaaaatt acattggttc tattatttta tgattacaaa cgatgctgca 700

 gtcatcattc ttgtacactt ctcattggtc actggtgtat ttctataggg 750

 tggggcctgg agagtagttg ttccagcata gtgttacat 789

<210> 3688
<211> 84
<212> PRT
<213> Homo sapien

<400> 3688
 His Thr Asp His Phe Arg Asn Thr Trp Leu Gln Pro Leu Pro Arg
   1               5                  10                  15

 Pro Glu Val Ser Phe Leu Thr Glu Tyr Leu Arg Lys Leu Lys Ala
                  20                  25                  30

 Cys Glu Gly Gly Gly Val Glu Ile Ala Ala Ala Ser Phe Pro Arg
                  35                  40                  45

 Ile Tyr Leu Met Gly Met Cys Ser Arg Gln Asp Arg Ile Gln Lys
                  50                  55                  60

 Asp Ile Asp Val Val Ile Gln Lys Ser Arg Ala Glu Asp Cys Leu
                  65                  70                  75

 Phe Ala Gly Pro Ala Trp Gln Asp Asp
                  80

<210> 3689
<211> 9618
<212> DNA
<213> Homo sapien

<400> 3689
 gcggccgctc ccccggagcg gctaaagcgg cggcgaccga ggcgagcaat 50

 gggcacggca gtctcggcag agcacaggcg cttcaccgcg gctgctcggg 100

 ctccgcgctg acctgcccgg gcggccgcct attgtctttc tccgcggcga 150

 aggtgaagag ttgtcccagc tcggcccgcg ggggagcccc gggagccgca 200

 cgtgtcctgg gtcatgaaac ttaatccaca gcaagctccc ttatatggtg 250

 attgtgttgt tacagtgctg cttgctgaag aggacaaagc tgaagatgat 300

 gtagtgtttt acttggtatt tttgggttcc accctccgtc actgtacaag 350

 tactcggaag gtcagttctg atacattgga gaccattgct cctggtcatg 400

 attgttgtga aacagtgaag gtgcagctct gtgcttccaa agagggcctt 450

 cccgtgtttg tggtggctga agaagacttt catttcgtcc aggatgaagc 500

 gtatgatgca gctcaattcc tagcaaccag tgctggaaat cagcaggctt 550

 tgaactttac ccgttttctt gaccagtcag gacccccatc tggggatgtg 600

 aattcccttg ataagaagtt ggtgctggca ttcaggcacc tgaagctgcc 650

 cacggagtgg aatgtattgg ggacagatca gagtttgcat gatgctggcc 700

 cgcgagagac attgatgcat tttgctgtgc ggctgggact gctgaggttg 750

 acgtggttcc tgttgcagaa gccaggtggc cgcggagctc tcagtatcca 800

 caaccaggaa ggggcgacgc ctgtgagctt ggccttggag cgaggctatc 850

 acaagctgca ccagcttcta accgaggaga atgctggaga accagactcc 900

 tggagcagtt tatcctatga aataccgtat ggagactgtt ctgtgaggca 950

 tcatcgagag ttggacatct atacattaac ctctgagtct gattcacatc 1000

 atgaacaccc atttcctgga gacggttgca ctggaccaat ttttaaactt 1050

 atgaacatcc aacagcaact aatgaaaaca aacctcaagc agatggacag 1100

 tcttatgccc ttaatgatga cagcacagga tccttccagt gccccagaga 1150

 cagatggcca gtttcttccc tgtgcaccgg agcccacgga ccctcagcga 1200

 ctttcttctt ctgaagagac tgagagcact cagtgctgcc cagggagccc 1250

 tgttgcacag actgaaagtc cctgtgattt gtcaagcata gttgaggagg 1300

 agaatacaga ccgttcctgt aggaagaaaa ataaaggcgt ggaaagaaaa 1350

 ggggaagagg tggagccagc acctattgtg gactctggaa ctgtatctga 1400

 tcaagacagc tgccttcaga gcttgcctga ttgtggagta aagggcacgg 1450

 aaggcctttc gtcctgtgga aacagaaatg aagaaactgg aacaaaatct 1500

 tctggaatgc ccacagacca ggagtccctg agcagtggag atgctgtgct 1550

 tcagagagac ttggtcatgg agccaggcac agcccagtat tcctctggag 1600

 gtgaactggg aggcatttca acaacaaatg tcagtacccc agacactgca 1650

 ggggaaatgg aacatgggct catgaaccca gatgccactg tttggaagaa 1700

 tgtgcttcag ggaggggaaa gtacaaagga aagatttgag aactctaata 1750

 ttggcacagc tggagcctct gacgtgcacg tcacaagtaa gcctgtggat 1800

 aaaatcagtg ttccaaactg tgcccctgct gccagttccc tggatggtaa 1850

 caaacctgct gagtcttcac ttgcatttag taatgaagaa acctccactg 1900

 aaaaaacagc agaaacggaa acttcacgaa gtcgtgagga gagtgctgat 1950

 gctccagtag atcagaattc tgtggtgatt ccagctgctg caaaagacaa 2000

 gatttcagat ggattagaac cttatactct cttagcagca ggcataggtg 2050

 aggcaatgtc accctcagat ttagcccttc ttgggctgga agaagatgta 2100

 atgccacacc agaactcaga aacaaattca tctcatgctc aaagccaaaa 2150

 gggcaaatcc tcacccattt gttctacaac tggagacgat aaactttgtg 2200

 cagactctgc atgtcaacag aacacagtga cttctagtgg cgatttggtt 2250

 gcaaaactgt gtgataacat agttagcgag tccgaaagca ccacagcaag 2300

 gcaacccagc tcacaagatc cacccgatgc ctcccactgt gaagacccac 2350

 aggctcatac agtcacctct gaccctgtaa gggataccca ggaacgtgcg 2400

 gatttttgtc ctttcaaagt ggtggataac aaaggccaac gaaaagatgt 2450

 gaaactagat aaacctttaa caaatatgct tgaggtggtt tcacatccac 2500

 atccagttgt ccctaaaatg gagaaagaac tggtgccaga ccaggcagta 2550

 atatcagaca gtactttctc tctggcaaac agtccaggca gtgaatcagt 2600

 aaccaaggat gacgcacttt cttttgtccc ctcccagaaa gaaaagggaa 2650

 cagcaactcc tgaactacat acagctacag attatagaga tggcccagat 2700

 ggaaattcga atgagcctga tacgcggcca ctagaagaca gggcagtagg 2750

 cctgtccaca tcctccactg ctgcagagct tcagcacggg atggggaata 2800

 ccagtctcac aggacttggt ggagagcatg aaggtcccgc ccctccagca 2850

 atcccagaag ctctgaatat caaggggaac actgactctt ccctgcaaag 2900

 tgtgggtaag gccactttgg ctttagattc agttttgact gaagaaggaa 2950

 aacttctggt ggtttcagaa agctctgcag ctcaggaaca agataaggat 3000

 aaagcggtga cctgttcctc tattaaggaa aatgctctct cttcaggaac 3050

 tttgcaggaa gagcagagaa caccacctcc tggacaagat actcaacaat 3100

 ttcatgaaaa atcaatctca gctgactgtg ccaaggacaa agcacttcag 3150

 ctaagtaatt caccgggtgc atcctctgcc tttcttaagg cagaaactga 3200

 acataacaag gaagtggccc cacaagtctc actgctgact caaggtgggg 3250

 ctgcccagag cctggtgcca ccaggagcaa gtctggccac agagtcaagg 3300

 caggaagcct tgggggcaga gcacaacagc tctgctctgt tgccatgtct 3350

 gttgccagat gggtctgatg ggtccgatgc tcttaactgc agtcagcctt 3400

 ctcctctgga tgttggagtg aagaacactc aatcccaggg aaaaactagt 3450

 gcctgtgagg tgagtggaga tgtgacggtg gatgttacag gggttaatgc 3500

 tctacaaggt atggctgagc ccagaagaga gaatatatca cacaacaccc 3550

 aagacatcct gattccaaac gtcttgttga gccaagagaa gaatgccgtt 3600

 ctaggtttgc cagtggctct acaggacaaa gctgtgactg acccacaggg 3650

 agttggaacc ccagagatga tacctcttga ttgggagaaa gggaagctgg 3700

 agggagcaga ccacagctgt accatgggtg acgctgagga agcccaaata 3750

 gacgatgaag cacatcctgt cctactgcag cctgttgcca aggagctccc 3800

 cacagacatg gagctctcag cccatgatga tggggcccca gctggtgtga 3850

 gggaagtcat gcgagccccg ccttcaggca gggaaaggag cactccctct 3900

 ctaccttgca tggtctctgc ccaggacgca cctctgccta agggggcaga 3950

 cttgatagag gaggctgcca gccgtatagt ggatgctgtc atcgaacaag 4000

 tcaaggccgc tggagcactg cttactgagg gggaggcctg tcacatgtca 4050

 ctgtccagcc ctgagttggg tcctctcact aaaggactag agagtgcttt 4100

 tacagaaaaa gtgagtactt tcccacctgg ggagagccta ccaatgggca 4150

 gtactcctga ggaagccacg gggagccttg caggatgttt tgctggaagg 4200

 gaggagccag agaagatcat tttacctgtc caggggcctg agccagcagc 4250

 agaaatgcca gacgtgaaag ctgaagatga agtggatttt agagcaagtt 4300

 caatttctga agaagtggct gtagggagca tagctgctac actgaagatg 4350

 aagcaaggcc caatgaccca ggcgataaac cgagaaaact ggtgtacaat 4400

 agagccatgc cctgatgcag catctcttct ggcttccaag cagagcccag 4450

 aatgtgagaa cttcctggat gttggactgg gcagagagtg tacctcaaaa 4500

 caaggtgtac ttaaaagaga atctgggagt gattctgacc tctttcactc 4550

 acccagtgat gacatggaca gcatcatctt cccaaagcca gaggaagagc 4600

 atttggcctg tgatatcacc ggatccagtt catccaccga tgacacggct 4650

 tcactggacc gacattcttc tcatggcagt gatgtgtctc tctcccagat 4700

 tttaaagcca aacaggtcaa gagatcggca aagccttgat ggattctaca 4750

 gccatgggat gggagctgag ggtcgagaaa gtgagagtga gcctgctgac 4800

 ccaggcgacg tggaggagga ggagatggac agtatcactg aagtgcctgc 4850

 aaactgctct gtcctaagga gctccatgcg ctctctttct cccttccgga 4900

 ggcacagctg ggggcctggg aaaaatgcag ccagcgatgc agaaatgaac 4950

 caccggagta tgagctggtg cccctctggt gtgcagtact ctgctggcct 5000

 gagtgctgac tttaattaca gaagtttcag tctagaaggc ttgacaggag 5050

 gagctggtgt cggaaacaag ccatcctcat ctctagaagt aagctctgca 5100

 aatgccgaag agctcagaca cccattcagt ggtgaggaac gggttgactc 5150

 tttggtgtca ctttcagaag aggatctgga gtcagaccag agagaacata 5200

 ggatgtttga tcagcagata tgtcacagat ctaagcagca gggatttaat 5250

 tactgtacat cagccatttc ctctccattg acaaaatcca tctcattaat 5300

 gacaatcagc catcctggat tggacaattc acggcccttc cacagtacct 5350

 tccacaatac cagtgctaat ctgactgaga gtataacaga agagaactat 5400

 aatttcctgc cacatagccc ctccaagaaa gattctgaat ggaagagtgg 5450

 aacaaaagtc agtcgtacat tcagctacat caagaataaa atgtctagca 5500

 gcaagaagag caaagaaaag gaaaaagaaa aagataagat taaggagaag 5550

 gagaaagatt ctaaagacaa ggagaaagat aagaagactg tcaacgggca 5600

 cactttcagt tccattcctg ttgtgggtcc catcagctgt agccagtgta 5650

 tgaagccctt caccaacaaa gatgcctata cttgtgcaaa ttgcagtgct 5700

 tttgtccaca aaggctgccg agaaagtcta gcctcctgtg caaaggtcaa 5750

 aatgaagcag cccaaaggga gccttcaggc acatgacaca tcatcactgc 5800

 ccacggtcat tatgagaaac aagccctcac agcccaagga gcgtcctcgg 5850

 tccgcagtcc tcctggtgga tgaaaccgct accaccccaa tatttgccaa 5900

 tagacgatcc cagcagagtg tctcgctctc caaaagtgtc tccatacaga 5950

 acattactgg agttggcaat gatgagaaca tgtcaaacac ctggaaattc 6000

 ctgtctcatt caacagactc actaaataaa atcagcaagg tcaatgagtc 6050

 aacagaatca cttactgatg agggagtagg tacagacatg aatgaaggac 6100

 aactactggg agactttgag attgagtcca aacagctgga agcagagtct 6150

 tggagtcgga taatagacag caagtttcta aaacagcaaa agaaagatgt 6200

 ggtcaaacgg caagaagtaa tatatgagtt gatgcagaca gagtttcatc 6250

 atgtccgcac tctcaagatc atgagtggtg tgtacagcca ggggatgatg 6300

 gcggatctgc tttttgagca gcagatggta gaaaagctgt tcccctgttt 6350

 ggatgagctg atcagtatcc atagccaatt cttccagagg attctggagc 6400

 ggaagaagga gtctctggtg gataaaagtg aaaagaactt tctcatcaag 6450

 aggatagggg atgtgcttgt aaatcagttt tcaggtgaga atgcagaacg 6500

 tttaaagaag acatatggca agttttgtgg gcaacataac cagtctgtaa 6550

 actacttcaa agacctttat gccaaggata agcgttttca agcctttgta 6600

 aagaagaaga tgagcagttc agttgttaga aggcttggaa ttccagagtg 6650

 catattgctt gtaactcagc ggattaccaa gtacccagtt ttattccaaa 6700

 gaatattgca gtgtaccaaa gacaatgaag tggagcagga agatctagca 6750

 cagtccttga gcctggtgaa ggatgtgatt ggagctgtag acagcaaagt 6800

 ggcaagttat gaaaagaaag tgcgtctcaa tgagatttat acaaagacag 6850

 atagcaagtc aatcatgagg atgaagagtg gtcagatgtt tgccaaggaa 6900

 gatttgaaac ggaagaagct tgtacgtgat gggagtgtgt ttctgaagaa 6950

 tgcagcagga aggttgaaag aggttcaagc agttcttctc actgacattt 7000

 tagttttcct tcaagaaaaa gaccagaagt acatctttgc atcattggac 7050

 cagaagtcaa cagtgatctc tttaaagaag ctgattgtga gagaagtggc 7100

 acatgaggag aaaggtttat tcctgatcag catggggatg acagatccag 7150

 agatggtaga agtccatgcc agctccaaag aggaacgaaa cagctggatt 7200

 cagatcattc aggacacaat caacaccctg aacagagatg aagatgaagg 7250

 aattcctagt gagaatgagg aagaaaagaa aatgttggac accagagccc 7300

 gagaattaaa agaacaactt caccagaagg accaaaaaat cctactcttg 7350

 ttggaagaga aggagatgat tttccgggac atggctgagt gcagcacccc 7400

 tctcccagag gattgctccc caacacatag ccctagagtt ctcttccgct 7450

 ccaacacaga agaggctctc aaaggaggac ctttaatgaa aagtgcaata 7500

 aatgaggtgg agatccttca gggtttggtg agtggaaatc tgggaggcac 7550

 acttgggccg actgtcagca gccccattga gcaagatgtg gtcagtcccg 7600

 tttccctgcc ccggagagca gagacctttg gaggatttga cagccatcag 7650

 atgaatgctt caaaaggagg cgagaaggaa gagggagatg atggccaaga 7700

 tcttaggaga acggaatcag atagtggcct aaaaaagggt ggaaatgcta 7750

 acctggtatt tatgcttaaa agaaacagtg agcaggttgt ccagagcgtt 7800

 gttcatctct acgagctcct cagcgctctg cagggtgtgg tgctgcagca 7850

 ggacagctac attgaggacc agaaactggt gctgagcgag agggcgctca 7900

 ctcgcagctt gtcccgcccg agctccctca ttgagcagga gaagcagcgc 7950

 agcctggaga agcagcgcca ggacctggcc aacctgcaga agcagcaggc 8000

 ccagtacctc gaggagaagc gcaggcgcga gcgtgagtgg gaagctcgtg 8050

 agagggagct gcgggagcgg gaggccctcc tggcccagcg cgaggaggag 8100

 gtgcagcagg ggcagcagga cctggaaaag gagcgggagg agctccagca 8150

 gaagaagggc acataccagt atgacctgga gcgactgcgt gctgcccaga 8200

 aacagcttga gagggaacag gagcagctgc gccgggaggc agagcggctc 8250

 agccagcggc agacagaacg ggacctgtgt caggtttccc atccacatac 8300

 caagctgatg aggatcccat cgttcttccc cagtcctgag gagcccccct 8350

 cgccatctgc accttccata gccaaatcag ggtcattgga ctcagaactt 8400

 tcagtgtccc caaaaaggaa cagcatctct cggacacaca aagataaggg 8450

 gccttttcac atactgagtt caaccagcca gacaaacaaa ggaccagaag 8500

 ggcagagcca ggcccctgcg tccacctctg cctctacccg cctgtttggg 8550

 ttaacaaagc caaaggaaaa gaaggagaaa aaaaagaaga acaaaaccag 8600

 ccgctctcag cccggtgatg gtcccgcgtc agaagtatca gcagagggtg 8650

 aagagatctt ctgctgaccc tcttcctctc tgctgaggca gctgcctcct 8700

 gatcctggcc agcccacctc tcctgctgtc cccgcgtgca caagtctctt 8750

 acactggacg cccactgctc ctcagcgtcc agtcctcctg ggcggcccca 8800

 ggtcctggac aataagcaac agatgatatt gagtgtcggg tggggaagga 8850

 ggcccagact ctgcttcggc catgatttgt gactgcccag gactctcagg 8900

 ttgggctggc cctactcagg attacactga aagtaatggc ctcgtaagta 8950

 caggtgatgg ttttggacac gtcaggaatt cctaaaggct gaaagagtgt 9000

 atccaagtaa ggtctgaacc tccgactgcc ttttatttgg gggaacacaa 9050

 aaccaaacag cagatgtttt ggacttgatc tgtgtacgta catggggacc 9100

 tgtctgcata tacacacggg gaatgccaga agaaggccca gtctgcacca 9150

 ggcgtctggt caacttagca caagggcagt gcctggacgg acccggagcc 9200

 cccgcatatc agcagttcac ccagtactcc tcagagactg gtttccctct 9250

 aaacccatcc cgggcacata ccacccctgt tttgcatgta tttctcattt 9300

 cattttaggg atgacaaaca tttgtgaaac cagtgagaga aggcttgatg 9350

 tgtataaaag acgtgatgtg caccacctcg atctcggtgt ttcaggcact 9400

 aaagcaacaa aacaacccat agtatctcat tttgtcatca gatccagaag 9450

 aaatatcctg gttttccagc atgtttaccc acatgttttg ggcatggata 9500

 aagtgaagag gcctactcac cattatccct gcagcgtgac accttttgat 9550

 tgtcactgac cactcagaag gggccacggc ctcctggctg tgttcctgag 9600

 aaaaaaaaaa aaaaaaaa 9618

<210> 3690
<211> 2817
<212> PRT
<213> Homo sapien

<400> 3690
 Met Lys Leu Asn Pro Gln Gln Ala Pro Leu Tyr Gly Asp Cys Val
   1               5                  10                  15

 Val Thr Val Leu Leu Ala Glu Glu Asp Lys Ala Glu Asp Asp Val
                  20                  25                  30

 Val Phe Tyr Leu Val Phe Leu Gly Ser Thr Leu Arg His Cys Thr
                  35                  40                  45

 Ser Thr Arg Lys Val Ser Ser Asp Thr Leu Glu Thr Ile Ala Pro
                  50                  55                  60

 Gly His Asp Cys Cys Glu Thr Val Lys Val Gln Leu Cys Ala Ser
                  65                  70                  75

 Lys Glu Gly Leu Pro Val Phe Val Val Ala Glu Glu Asp Phe His
                  80                  85                  90

 Phe Val Gln Asp Glu Ala Tyr Asp Ala Ala Gln Phe Leu Ala Thr
                  95                 100                 105

 Ser Ala Gly Asn Gln Gln Ala Leu Asn Phe Thr Arg Phe Leu Asp
                 110                 115                 120

 Gln Ser Gly Pro Pro Ser Gly Asp Val Asn Ser Leu Asp Lys Lys
                 125                 130                 135

 Leu Val Leu Ala Phe Arg His Leu Lys Leu Pro Thr Glu Trp Asn
                 140                 145                 150

 Val Leu Gly Thr Asp Gln Ser Leu His Asp Ala Gly Pro Arg Glu
                 155                 160                 165

 Thr Leu Met His Phe Ala Val Arg Leu Gly Leu Leu Arg Leu Thr
                 170                 175                 180

 Trp Phe Leu Leu Gln Lys Pro Gly Gly Arg Gly Ala Leu Ser Ile
                 185                 190                 195

 His Asn Gln Glu Gly Ala Thr Pro Val Ser Leu Ala Leu Glu Arg
                 200                 205                 210

 Gly Tyr His Lys Leu His Gln Leu Leu Thr Glu Glu Asn Ala Gly
                 215                 220                 225

 Glu Pro Asp Ser Trp Ser Ser Leu Ser Tyr Glu Ile Pro Tyr Gly
                 230                 235                 240

 Asp Cys Ser Val Arg His His Arg Glu Leu Asp Ile Tyr Thr Leu
                 245                 250                 255

 Thr Ser Glu Ser Asp Ser His His Glu His Pro Phe Pro Gly Asp
                 260                 265                 270

 Gly Cys Thr Gly Pro Ile Phe Lys Leu Met Asn Ile Gln Gln Gln
                 275                 280                 285

 Leu Met Lys Thr Asn Leu Lys Gln Met Asp Ser Leu Met Pro Leu
                 290                 295                 300

 Met Met Thr Ala Gln Asp Pro Ser Ser Ala Pro Glu Thr Asp Gly
                 305                 310                 315

 Gln Phe Leu Pro Cys Ala Pro Glu Pro Thr Asp Pro Gln Arg Leu
                 320                 325                 330

 Ser Ser Ser Glu Glu Thr Glu Ser Thr Gln Cys Cys Pro Gly Ser
                 335                 340                 345

 Pro Val Ala Gln Thr Glu Ser Pro Cys Asp Leu Ser Ser Ile Val
                 350                 355                 360

 Glu Glu Glu Asn Thr Asp Arg Ser Cys Arg Lys Lys Asn Lys Gly
                 365                 370                 375

 Val Glu Arg Lys Gly Glu Glu Val Glu Pro Ala Pro Ile Val Asp
                 380                 385                 390

 Ser Gly Thr Val Ser Asp Gln Asp Ser Cys Leu Gln Ser Leu Pro
                 395                 400                 405

 Asp Cys Gly Val Lys Gly Thr Glu Gly Leu Ser Ser Cys Gly Asn
                 410                 415                 420

 Arg Asn Glu Glu Thr Gly Thr Lys Ser Ser Gly Met Pro Thr Asp
                 425                 430                 435

 Gln Glu Ser Leu Ser Ser Gly Asp Ala Val Leu Gln Arg Asp Leu
                 440                 445                 450

 Val Met Glu Pro Gly Thr Ala Gln Tyr Ser Ser Gly Gly Glu Leu
                 455                 460                 465

 Gly Gly Ile Ser Thr Thr Asn Val Ser Thr Pro Asp Thr Ala Gly
                 470                 475                 480

 Glu Met Glu His Gly Leu Met Asn Pro Asp Ala Thr Val Trp Lys
                 485                 490                 495

 Asn Val Leu Gln Gly Gly Glu Ser Thr Lys Glu Arg Phe Glu Asn
                 500                 505                 510

 Ser Asn Ile Gly Thr Ala Gly Ala Ser Asp Val His Val Thr Ser
                 515                 520                 525

 Lys Pro Val Asp Lys Ile Ser Val Pro Asn Cys Ala Pro Ala Ala
                 530                 535                 540

 Ser Ser Leu Asp Gly Asn Lys Pro Ala Glu Ser Ser Leu Ala Phe
                 545                 550                 555

 Ser Asn Glu Glu Thr Ser Thr Glu Lys Thr Ala Glu Thr Glu Thr
                 560                 565                 570

 Ser Arg Ser Arg Glu Glu Ser Ala Asp Ala Pro Val Asp Gln Asn
                 575                 580                 585

 Ser Val Val Ile Pro Ala Ala Ala Lys Asp Lys Ile Ser Asp Gly
                 590                 595                 600

 Leu Glu Pro Tyr Thr Leu Leu Ala Ala Gly Ile Gly Glu Ala Met
                 605                 610                 615

 Ser Pro Ser Asp Leu Ala Leu Leu Gly Leu Glu Glu Asp Val Met
                 620                 625                 630

 Pro His Gln Asn Ser Glu Thr Asn Ser Ser His Ala Gln Ser Gln
                 635                 640                 645

 Lys Gly Lys Ser Ser Pro Ile Cys Ser Thr Thr Gly Asp Asp Lys
                 650                 655                 660

 Leu Cys Ala Asp Ser Ala Cys Gln Gln Asn Thr Val Thr Ser Ser
                 665                 670                 675

 Gly Asp Leu Val Ala Lys Leu Cys Asp Asn Ile Val Ser Glu Ser
                 680                 685                 690

 Glu Ser Thr Thr Ala Arg Gln Pro Ser Ser Gln Asp Pro Pro Asp
                 695                 700                 705

 Ala Ser His Cys Glu Asp Pro Gln Ala His Thr Val Thr Ser Asp
                 710                 715                 720

 Pro Val Arg Asp Thr Gln Glu Arg Ala Asp Phe Cys Pro Phe Lys
                 725                 730                 735

 Val Val Asp Asn Lys Gly Gln Arg Lys Asp Val Lys Leu Asp Lys
                 740                 745                 750

 Pro Leu Thr Asn Met Leu Glu Val Val Ser His Pro His Pro Val
                 755                 760                 765

 Val Pro Lys Met Glu Lys Glu Leu Val Pro Asp Gln Ala Val Ile
                 770                 775                 780

 Ser Asp Ser Thr Phe Ser Leu Ala Asn Ser Pro Gly Ser Glu Ser
                 785                 790                 795

 Val Thr Lys Asp Asp Ala Leu Ser Phe Val Pro Ser Gln Lys Glu
                 800                 805                 810

 Lys Gly Thr Ala Thr Pro Glu Leu His Thr Ala Thr Asp Tyr Arg
                 815                 820                 825

 Asp Gly Pro Asp Gly Asn Ser Asn Glu Pro Asp Thr Arg Pro Leu
                 830                 835                 840

 Glu Asp Arg Ala Val Gly Leu Ser Thr Ser Ser Thr Ala Ala Glu
                 845                 850                 855

 Leu Gln His Gly Met Gly Asn Thr Ser Leu Thr Gly Leu Gly Gly
                 860                 865                 870

 Glu His Glu Gly Pro Ala Pro Pro Ala Ile Pro Glu Ala Leu Asn
                 875                 880                 885

 Ile Lys Gly Asn Thr Asp Ser Ser Leu Gln Ser Val Gly Lys Ala
                 890                 895                 900

 Thr Leu Ala Leu Asp Ser Val Leu Thr Glu Glu Gly Lys Leu Leu
                 905                 910                 915

 Val Val Ser Glu Ser Ser Ala Ala Gln Glu Gln Asp Lys Asp Lys
                 920                 925                 930

 Ala Val Thr Cys Ser Ser Ile Lys Glu Asn Ala Leu Ser Ser Gly
                 935                 940                 945

 Thr Leu Gln Glu Glu Gln Arg Thr Pro Pro Pro Gly Gln Asp Thr
                 950                 955                 960

 Gln Gln Phe His Glu Lys Ser Ile Ser Ala Asp Cys Ala Lys Asp
                 965                 970                 975

 Lys Ala Leu Gln Leu Ser Asn Ser Pro Gly Ala Ser Ser Ala Phe
                 980                 985                 990

 Leu Lys Ala Glu Thr Glu His Asn Lys Glu Val Ala Pro Gln Val
                 995                1000                1005

 Ser Leu Leu Thr Gln Gly Gly Ala Ala Gln Ser Leu Val Pro Pro
                1010                1015                1020

 Gly Ala Ser Leu Ala Thr Glu Ser Arg Gln Glu Ala Leu Gly Ala
                1025                1030                1035

 Glu His Asn Ser Ser Ala Leu Leu Pro Cys Leu Leu Pro Asp Gly
                1040                1045                1050

 Ser Asp Gly Ser Asp Ala Leu Asn Cys Ser Gln Pro Ser Pro Leu
                1055                1060                1065

 Asp Val Gly Val Lys Asn Thr Gln Ser Gln Gly Lys Thr Ser Ala
                1070                1075                1080

 Cys Glu Val Ser Gly Asp Val Thr Val Asp Val Thr Gly Val Asn
                1085                1090                1095

 Ala Leu Gln Gly Met Ala Glu Pro Arg Arg Glu Asn Ile Ser His
                1100                1105                1110

 Asn Thr Gln Asp Ile Leu Ile Pro Asn Val Leu Leu Ser Gln Glu
                1115                1120                1125

 Lys Asn Ala Val Leu Gly Leu Pro Val Ala Leu Gln Asp Lys Ala
                1130                1135                1140

 Val Thr Asp Pro Gln Gly Val Gly Thr Pro Glu Met Ile Pro Leu
                1145                1150                1155

 Asp Trp Glu Lys Gly Lys Leu Glu Gly Ala Asp His Ser Cys Thr
                1160                1165                1170

 Met Gly Asp Ala Glu Glu Ala Gln Ile Asp Asp Glu Ala His Pro
                1175                1180                1185

 Val Leu Leu Gln Pro Val Ala Lys Glu Leu Pro Thr Asp Met Glu
                1190                1195                1200

 Leu Ser Ala His Asp Asp Gly Ala Pro Ala Gly Val Arg Glu Val
                1205                1210                1215

 Met Arg Ala Pro Pro Ser Gly Arg Glu Arg Ser Thr Pro Ser Leu
                1220                1225                1230

 Pro Cys Met Val Ser Ala Gln Asp Ala Pro Leu Pro Lys Gly Ala
                1235                1240                1245

 Asp Leu Ile Glu Glu Ala Ala Ser Arg Ile Val Asp Ala Val Ile
                1250                1255                1260

 Glu Gln Val Lys Ala Ala Gly Ala Leu Leu Thr Glu Gly Glu Ala
                1265                1270                1275

 Cys His Met Ser Leu Ser Ser Pro Glu Leu Gly Pro Leu Thr Lys
                1280                1285                1290

 Gly Leu Glu Ser Ala Phe Thr Glu Lys Val Ser Thr Phe Pro Pro
                1295                1300                1305

 Gly Glu Ser Leu Pro Met Gly Ser Thr Pro Glu Glu Ala Thr Gly
                1310                1315                1320

 Ser Leu Ala Gly Cys Phe Ala Gly Arg Glu Glu Pro Glu Lys Ile
                1325                1330                1335

 Ile Leu Pro Val Gln Gly Pro Glu Pro Ala Ala Glu Met Pro Asp
                1340                1345                1350

 Val Lys Ala Glu Asp Glu Val Asp Phe Arg Ala Ser Ser Ile Ser
                1355                1360                1365

 Glu Glu Val Ala Val Gly Ser Ile Ala Ala Thr Leu Lys Met Lys
                1370                1375                1380

 Gln Gly Pro Met Thr Gln Ala Ile Asn Arg Glu Asn Trp Cys Thr
                1385                1390                1395

 Ile Glu Pro Cys Pro Asp Ala Ala Ser Leu Leu Ala Ser Lys Gln
                1400                1405                1410

 Ser Pro Glu Cys Glu Asn Phe Leu Asp Val Gly Leu Gly Arg Glu
                1415                1420                1425

 Cys Thr Ser Lys Gln Gly Val Leu Lys Arg Glu Ser Gly Ser Asp
                1430                1435                1440

 Ser Asp Leu Phe His Ser Pro Ser Asp Asp Met Asp Ser Ile Ile
                1445                1450                1455

 Phe Pro Lys Pro Glu Glu Glu His Leu Ala Cys Asp Ile Thr Gly
                1460                1465                1470

 Ser Ser Ser Ser Thr Asp Asp Thr Ala Ser Leu Asp Arg His Ser
                1475                1480                1485

 Ser His Gly Ser Asp Val Ser Leu Ser Gln Ile Leu Lys Pro Asn
                1490                1495                1500

 Arg Ser Arg Asp Arg Gln Ser Leu Asp Gly Phe Tyr Ser His Gly
                1505                1510                1515

 Met Gly Ala Glu Gly Arg Glu Ser Glu Ser Glu Pro Ala Asp Pro
                1520                1525                1530

 Gly Asp Val Glu Glu Glu Glu Met Asp Ser Ile Thr Glu Val Pro
                1535                1540                1545

 Ala Asn Cys Ser Val Leu Arg Ser Ser Met Arg Ser Leu Ser Pro
                1550                1555                1560

 Phe Arg Arg His Ser Trp Gly Pro Gly Lys Asn Ala Ala Ser Asp
                1565                1570                1575

 Ala Glu Met Asn His Arg Ser Met Ser Trp Cys Pro Ser Gly Val
                1580                1585                1590

 Gln Tyr Ser Ala Gly Leu Ser Ala Asp Phe Asn Tyr Arg Ser Phe
                1595                1600                1605

 Ser Leu Glu Gly Leu Thr Gly Gly Ala Gly Val Gly Asn Lys Pro
                1610                1615                1620

 Ser Ser Ser Leu Glu Val Ser Ser Ala Asn Ala Glu Glu Leu Arg
                1625                1630                1635

 His Pro Phe Ser Gly Glu Glu Arg Val Asp Ser Leu Val Ser Leu
                1640                1645                1650

 Ser Glu Glu Asp Leu Glu Ser Asp Gln Arg Glu His Arg Met Phe
                1655                1660                1665

 Asp Gln Gln Ile Cys His Arg Ser Lys Gln Gln Gly Phe Asn Tyr
                1670                1675                1680

 Cys Thr Ser Ala Ile Ser Ser Pro Leu Thr Lys Ser Ile Ser Leu
                1685                1690                1695

 Met Thr Ile Ser His Pro Gly Leu Asp Asn Ser Arg Pro Phe His
                1700                1705                1710

 Ser Thr Phe His Asn Thr Ser Ala Asn Leu Thr Glu Ser Ile Thr
                1715                1720                1725

 Glu Glu Asn Tyr Asn Phe Leu Pro His Ser Pro Ser Lys Lys Asp
                1730                1735                1740

 Ser Glu Trp Lys Ser Gly Thr Lys Val Ser Arg Thr Phe Ser Tyr
                1745                1750                1755

 Ile Lys Asn Lys Met Ser Ser Ser Lys Lys Ser Lys Glu Lys Glu
                1760                1765                1770

 Lys Glu Lys Asp Lys Ile Lys Glu Lys Glu Lys Asp Ser Lys Asp
                1775                1780                1785

 Lys Glu Lys Asp Lys Lys Thr Val Asn Gly His Thr Phe Ser Ser
                1790                1795                1800

 Ile Pro Val Val Gly Pro Ile Ser Cys Ser Gln Cys Met Lys Pro
                1805                1810                1815

 Phe Thr Asn Lys Asp Ala Tyr Thr Cys Ala Asn Cys Ser Ala Phe
                1820                1825                1830

 Val His Lys Gly Cys Arg Glu Ser Leu Ala Ser Cys Ala Lys Val
                1835                1840                1845

 Lys Met Lys Gln Pro Lys Gly Ser Leu Gln Ala His Asp Thr Ser
                1850                1855                1860

 Ser Leu Pro Thr Val Ile Met Arg Asn Lys Pro Ser Gln Pro Lys
                1865                1870                1875

 Glu Arg Pro Arg Ser Ala Val Leu Leu Val Asp Glu Thr Ala Thr
                1880                1885                1890

 Thr Pro Ile Phe Ala Asn Arg Arg Ser Gln Gln Ser Val Ser Leu
                1895                1900                1905

 Ser Lys Ser Val Ser Ile Gln Asn Ile Thr Gly Val Gly Asn Asp
                1910                1915                1920

 Glu Asn Met Ser Asn Thr Trp Lys Phe Leu Ser His Ser Thr Asp
                1925                1930                1935

 Ser Leu Asn Lys Ile Ser Lys Val Asn Glu Ser Thr Glu Ser Leu
                1940                1945                1950

 Thr Asp Glu Gly Val Gly Thr Asp Met Asn Glu Gly Gln Leu Leu
                1955                1960                1965

 Gly Asp Phe Glu Ile Glu Ser Lys Gln Leu Glu Ala Glu Ser Trp
                1970                1975                1980

 Ser Arg Ile Ile Asp Ser Lys Phe Leu Lys Gln Gln Lys Lys Asp
                1985                1990                1995

 Val Val Lys Arg Gln Glu Val Ile Tyr Glu Leu Met Gln Thr Glu
                2000                2005                2010

 Phe His His Val Arg Thr Leu Lys Ile Met Ser Gly Val Tyr Ser
                2015                2020                2025

 Gln Gly Met Met Ala Asp Leu Leu Phe Glu Gln Gln Met Val Glu
                2030                2035                2040

 Lys Leu Phe Pro Cys Leu Asp Glu Leu Ile Ser Ile His Ser Gln
                2045                2050                2055

 Phe Phe Gln Arg Ile Leu Glu Arg Lys Lys Glu Ser Leu Val Asp
                2060                2065                2070

 Lys Ser Glu Lys Asn Phe Leu Ile Lys Arg Ile Gly Asp Val Leu
                2075                2080                2085

 Val Asn Gln Phe Ser Gly Glu Asn Ala Glu Arg Leu Lys Lys Thr
                2090                2095                2100

 Tyr Gly Lys Phe Cys Gly Gln His Asn Gln Ser Val Asn Tyr Phe
                2105                2110                2115

 Lys Asp Leu Tyr Ala Lys Asp Lys Arg Phe Gln Ala Phe Val Lys
                2120                2125                2130

 Lys Lys Met Ser Ser Ser Val Val Arg Arg Leu Gly Ile Pro Glu
                2135                2140                2145

 Cys Ile Leu Leu Val Thr Gln Arg Ile Thr Lys Tyr Pro Val Leu
                2150                2155                2160

 Phe Gln Arg Ile Leu Gln Cys Thr Lys Asp Asn Glu Val Glu Gln
                2165                2170                2175

 Glu Asp Leu Ala Gln Ser Leu Ser Leu Val Lys Asp Val Ile Gly
                2180                2185                2190

 Ala Val Asp Ser Lys Val Ala Ser Tyr Glu Lys Lys Val Arg Leu
                2195                2200                2205

 Asn Glu Ile Tyr Thr Lys Thr Asp Ser Lys Ser Ile Met Arg Met
                2210                2215                2220

 Lys Ser Gly Gln Met Phe Ala Lys Glu Asp Leu Lys Arg Lys Lys
                2225                2230                2235

 Leu Val Arg Asp Gly Ser Val Phe Leu Lys Asn Ala Ala Gly Arg
                2240                2245                2250

 Leu Lys Glu Val Gln Ala Val Leu Leu Thr Asp Ile Leu Val Phe
                2255                2260                2265

 Leu Gln Glu Lys Asp Gln Lys Tyr Ile Phe Ala Ser Leu Asp Gln
                2270                2275                2280

 Lys Ser Thr Val Ile Ser Leu Lys Lys Leu Ile Val Arg Glu Val
                2285                2290                2295

 Ala His Glu Glu Lys Gly Leu Phe Leu Ile Ser Met Gly Met Thr
                2300                2305                2310

 Asp Pro Glu Met Val Glu Val His Ala Ser Ser Lys Glu Glu Arg
                2315                2320                2325

 Asn Ser Trp Ile Gln Ile Ile Gln Asp Thr Ile Asn Thr Leu Asn
                2330                2335                2340

 Arg Asp Glu Asp Glu Gly Ile Pro Ser Glu Asn Glu Glu Glu Lys
                2345                2350                2355

 Lys Met Leu Asp Thr Arg Ala Arg Glu Leu Lys Glu Gln Leu His
                2360                2365                2370

 Gln Lys Asp Gln Lys Ile Leu Leu Leu Leu Glu Glu Lys Glu Met
                2375                2380                2385

 Ile Phe Arg Asp Met Ala Glu Cys Ser Thr Pro Leu Pro Glu Asp
                2390                2395                2400

 Cys Ser Pro Thr His Ser Pro Arg Val Leu Phe Arg Ser Asn Thr
                2405                2410                2415

 Glu Glu Ala Leu Lys Gly Gly Pro Leu Met Lys Ser Ala Ile Asn
                2420                2425                2430

 Glu Val Glu Ile Leu Gln Gly Leu Val Ser Gly Asn Leu Gly Gly
                2435                2440                2445

 Thr Leu Gly Pro Thr Val Ser Ser Pro Ile Glu Gln Asp Val Val
                2450                2455                2460

 Ser Pro Val Ser Leu Pro Arg Arg Ala Glu Thr Phe Gly Gly Phe
                2465                2470                2475

 Asp Ser His Gln Met Asn Ala Ser Lys Gly Gly Glu Lys Glu Glu
                2480                2485                2490

 Gly Asp Asp Gly Gln Asp Leu Arg Arg Thr Glu Ser Asp Ser Gly
                2495                2500                2505

 Leu Lys Lys Gly Gly Asn Ala Asn Leu Val Phe Met Leu Lys Arg
                2510                2515                2520

 Asn Ser Glu Gln Val Val Gln Ser Val Val His Leu Tyr Glu Leu
                2525                2530                2535

 Leu Ser Ala Leu Gln Gly Val Val Leu Gln Gln Asp Ser Tyr Ile
                2540                2545                2550

 Glu Asp Gln Lys Leu Val Leu Ser Glu Arg Ala Leu Thr Arg Ser
                2555                2560                2565

 Leu Ser Arg Pro Ser Ser Leu Ile Glu Gln Glu Lys Gln Arg Ser
                2570                2575                2580

 Leu Glu Lys Gln Arg Gln Asp Leu Ala Asn Leu Gln Lys Gln Gln
                2585                2590                2595

 Ala Gln Tyr Leu Glu Glu Lys Arg Arg Arg Glu Arg Glu Trp Glu
                2600                2605                2610

 Ala Arg Glu Arg Glu Leu Arg Glu Arg Glu Ala Leu Leu Ala Gln
                2615                2620                2625

 Arg Glu Glu Glu Val Gln Gln Gly Gln Gln Asp Leu Glu Lys Glu
                2630                2635                2640

 Arg Glu Glu Leu Gln Gln Lys Lys Gly Thr Tyr Gln Tyr Asp Leu
                2645                2650                2655

 Glu Arg Leu Arg Ala Ala Gln Lys Gln Leu Glu Arg Glu Gln Glu
                2660                2665                2670

 Gln Leu Arg Arg Glu Ala Glu Arg Leu Ser Gln Arg Gln Thr Glu
                2675                2680                2685

 Arg Asp Leu Cys Gln Val Ser His Pro His Thr Lys Leu Met Arg
                2690                2695                2700

 Ile Pro Ser Phe Phe Pro Ser Pro Glu Glu Pro Pro Ser Pro Ser
                2705                2710                2715

 Ala Pro Ser Ile Ala Lys Ser Gly Ser Leu Asp Ser Glu Leu Ser
                2720                2725                2730

 Val Ser Pro Lys Arg Asn Ser Ile Ser Arg Thr His Lys Asp Lys
                2735                2740                2745

 Gly Pro Phe His Ile Leu Ser Ser Thr Ser Gln Thr Asn Lys Gly
                2750                2755                2760

 Pro Glu Gly Gln Ser Gln Ala Pro Ala Ser Thr Ser Ala Ser Thr
                2765                2770                2775

 Arg Leu Phe Gly Leu Thr Lys Pro Lys Glu Lys Lys Glu Lys Lys
                2780                2785                2790

 Lys Lys Asn Lys Thr Ser Arg Ser Gln Pro Gly Asp Gly Pro Ala
                2795                2800                2805

 Ser Glu Val Ser Ala Glu Gly Glu Glu Ile Phe Cys
                2810                2815

<210> 3691
<211> 2967
<212> DNA
<213> Homo sapien

<400> 3691
 cccagccagc cctgcacccc agagctccct gcagggccta gagcccttca 50

 agaggagagt ctggggatgg aggcccaggt ggagagggcc atggaaggga 100

 actcttcaga ccaggagcag tccccagagg atgaggatga aggcccagct 150

 gaggaggttc caacccagat gccagagcag aaccccacac atgcactgcc 200

 agagtcccct cgcctgaccc tgcagcccaa gccagtcgtg ggccacttct 250

 cagcacggga actggatggg gaccgttcta agcagttggc cctaaaggtg 300

 ctgtgcgttg cccagcggca gtactccctg ctccaagcag ccaacctcct 350

 gacgcccgac atgatcacag agtttgagac cctacagcag ctggtgcaag 400

 aggaaaaaat tgagcctggg gcagaggcct tgaggacttc aggcctggcc 450

 aggggggcac ctctggctca ggagctgtgt tcagagtcaa tccctgtgcc 500

 gtctcctctc tgcccagagc ctccaggata cactggccct gtgacccgga 550

 ctatggcgag gcgactgagt ggccccctgc acaccctggg aatcccgcct 600

 ggacccaact gcaccccagc ccaggggtcc cgatggccca tggagaagaa 650

 gaggaggaga ccaagcgcct tggaggcaga cagtcccatg gccccaaagc 700

 ggggcaccaa gcgccagcgc cagtccttcc tgccctgcct aaggagaggg 750

 tctctgcctg acacccaacc ttcacagggg cccagcaccc ccaaaggaga 800

 aagggcctcc tccccctgcc attcccctcg cgtttgccca gccacagtca 850

 tcaaaagccg ggtgcccctg ggcccttccg ccatgcagaa ctgctccacc 900

 ccgctggctc tgcccactcg agacctcaat gccacctttg atctctctga 950

 ggagcctccc tcaaagccca gtttccatga atgcattggc tgggacaaaa 1000

 taccccagga gctgagcagg ctggaccagc ccttcatccc cagggcacct 1050

 gtgcccctgt tcaccatgaa gggccccaag ccaacatctt ccctccctgg 1100

 gacctctgcc tgcaagaaga agcgcgttgc gagttcctca gtctcccatg 1150

 gccgcagccg catcgcccgc ctccccagca gcactttgaa gaggccagct 1200

 gggccccttg tactcccagg tgactggcac tagggacagg gatagcctgg 1250

 gccatggagg ccgatgaaga caagaaggag gaggggacgg ggagctgaga 1300

 cccagaagaa aggagggcct agggtattgc caagcatctc agggatgctg 1350

 ctgatgagac aggtgggagg tgggctggag gacggggaca gagcgtcact 1400

 ttccttcctc gctgcactcc ccgccaccca tccaactggc ctgcagagct 1450

 gcccttgagt cccctgtgcc ctagcaaccg gaggaatgga aaggacctca 1500

 tcagggtggg gagagcactc tcagcaggga acggcgtcac caaggtgtcc 1550

 tgaccgccag aatgtcctga ccaccaaggt gtcctaacct accggcccct 1600

 ctgctggata cccctcttgg acctgtagcc acctgcacca ggagctggac 1650

 ctgccttcct tacctgggag caattagtgc caacacacct ttgctgtatt 1700

 aacatccctc cccagacatc catcctgcta ctcaccctct gttaatctcc 1750

 tgttacactc agcttcttgg catgtacata ttcatttgtg agtgttaatg 1800

 tgctgctgtt ttttgttttt tggtggtttt tgttttttgt tttttttgtt 1850

 ttgagatgga gtcttactct gtcgcccagg ctggagtgca gtggtacgat 1900

 cttggctcac tgcaacctcc gcctcctggg ttcaagtaat tctcctgcct 1950

 cagctttcca agtagctggg attacaggca cccatcacca cacccagcta 2000

 attttcgtct ttttaataga gagggggttt ttccatgttg gccaggctgg 2050

 tcttgaactc ctgacctcag gtgatccgcc tgcctcagct tcccaaagtg 2100

 ctgagattac aggcatgagc taccacgcct ggcccgtgtt gctgttttaa 2150

 aggtgctgcc atgttccccc atcttttttt tttttgagat ggagtctcgc 2200

 tctgtcgccc aggctggagt gcagtggtgg cgatcttggc tcactgcaag 2250

 ctccgcctcc caggttcaca ccattctcct gcctcagcct cccaagtagc 2300

 tgggactaca ggcgcccacc accacgcccg gctaattttt tgtattttta 2350

 gtagagatgg ggtttcaccg tgttagccag gctggtctcg atctgacctc 2400

 atgatccacc cgcctcggcc tcccaaagtg ctgggattac aggcgtgagc 2450

 cactgcgccc ggcctcccct ctcatttatg atgccctctg tgcaggcaga 2500

 cggctcttgg gctcttttcc ccacctgtct ctaacacagg ccccacggtg 2550

 atggccacag gcagtagagg aggaatgagg atgggttggg gagcggggag 2600

 tcgcggcttg gctcttcctg gtttctgaga gggacatctt catccctact 2650

 ccccttggtc cccaaccaca gtcctggtga agatgtggat gataatggtg 2700

 ccttgatttc caaatgaaga cagctttatt gcttaactct attgtacata 2750

 ggatacacgt tcagtgtaaa ataaagtgta aaggggaatt caggcttaat 2800

 gctgcaccta gatataaatg ctaatgatac ttgggtttat agccttctga 2850

 tcctttattt ctgcatatat atatagatat atacatatat ttttggtata 2900

 acaataaacc gtctccatca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2950

 aaaaaaaaaa aaaaaaa 2967

<210> 3692
<211> 410
<212> PRT
<213> Homo sapien

<400> 3692
 Pro Ser Gln Pro Cys Thr Pro Glu Leu Pro Ala Gly Pro Arg Ala
   1               5                  10                  15

 Leu Gln Glu Glu Ser Leu Gly Met Glu Ala Gln Val Glu Arg Ala
                  20                  25                  30

 Met Glu Gly Asn Ser Ser Asp Gln Glu Gln Ser Pro Glu Asp Glu
                  35                  40                  45

 Asp Glu Gly Pro Ala Glu Glu Val Pro Thr Gln Met Pro Glu Gln
                  50                  55                  60

 Asn Pro Thr His Ala Leu Pro Glu Ser Pro Arg Leu Thr Leu Gln
                  65                  70                  75

 Pro Lys Pro Val Val Gly His Phe Ser Ala Arg Glu Leu Asp Gly
                  80                  85                  90

 Asp Arg Ser Lys Gln Leu Ala Leu Lys Val Leu Cys Val Ala Gln
                  95                 100                 105

 Arg Gln Tyr Ser Leu Leu Gln Ala Ala Asn Leu Leu Thr Pro Asp
                 110                 115                 120

 Met Ile Thr Glu Phe Glu Thr Leu Gln Gln Leu Val Gln Glu Glu
                 125                 130                 135

 Lys Ile Glu Pro Gly Ala Glu Ala Leu Arg Thr Ser Gly Leu Ala
                 140                 145                 150

 Arg Gly Ala Pro Leu Ala Gln Glu Leu Cys Ser Glu Ser Ile Pro
                 155                 160                 165

 Val Pro Ser Pro Leu Cys Pro Glu Pro Pro Gly Tyr Thr Gly Pro
                 170                 175                 180

 Val Thr Arg Thr Met Ala Arg Arg Leu Ser Gly Pro Leu His Thr
                 185                 190                 195

 Leu Gly Ile Pro Pro Gly Pro Asn Cys Thr Pro Ala Gln Gly Ser
                 200                 205                 210

 Arg Trp Pro Met Glu Lys Lys Arg Arg Arg Pro Ser Ala Leu Glu
                 215                 220                 225

 Ala Asp Ser Pro Met Ala Pro Lys Arg Gly Thr Lys Arg Gln Arg
                 230                 235                 240

 Gln Ser Phe Leu Pro Cys Leu Arg Arg Gly Ser Leu Pro Asp Thr
                 245                 250                 255

 Gln Pro Ser Gln Gly Pro Ser Thr Pro Lys Gly Glu Arg Ala Ser
                 260                 265                 270

 Ser Pro Cys His Ser Pro Arg Val Cys Pro Ala Thr Val Ile Lys
                 275                 280                 285

 Ser Arg Val Pro Leu Gly Pro Ser Ala Met Gln Asn Cys Ser Thr
                 290                 295                 300

 Pro Leu Ala Leu Pro Thr Arg Asp Leu Asn Ala Thr Phe Asp Leu
                 305                 310                 315

 Ser Glu Glu Pro Pro Ser Lys Pro Ser Phe His Glu Cys Ile Gly
                 320                 325                 330

 Trp Asp Lys Ile Pro Gln Glu Leu Ser Arg Leu Asp Gln Pro Phe
                 335                 340                 345

 Ile Pro Arg Ala Pro Val Pro Leu Phe Thr Met Lys Gly Pro Lys
                 350                 355                 360

 Pro Thr Ser Ser Leu Pro Gly Thr Ser Ala Cys Lys Lys Lys Arg
                 365                 370                 375

 Val Ala Ser Ser Ser Val Ser His Gly Arg Ser Arg Ile Ala Arg
                 380                 385                 390

 Leu Pro Ser Ser Thr Leu Lys Arg Pro Ala Gly Pro Leu Val Leu
                 395                 400                 405

 Pro Gly Asp Trp His
                 410

<210> 3693
<211> 2794
<212> DNA
<213> Homo sapien

<400> 3693
 gaccagccgt gcaaatctct agaagatgac ggtgttcttt aaaacgcttc 50

 gaaatcactg gaagaaaact acagctgggc tctgcctgct gacctgggga 100

 ggccattggc tctatggaaa acactgtgat aacctcctaa ggagagcagc 150

 ctgtcaagaa gctcaggtgt ttggcaatca actcattcct cccaatgcac 200

 aagtgaagaa ggccactgtt tttctcaatc ctgcagcttg caaaggaaaa 250

 gctaggactc tatttgaaaa aaatgctgcc ccgattttac atttatctgg 300

 catggatgtg actattgtta agacagatta tgagggacaa gccaagaaac 350

 tcctggaact gatggaaaac acggatgtga tcattgttgc aggaggagat 400

 gggacactgc aggaggttgt tactggtgtt cttcgacgaa cagatgaggc 450

 taccttcagt aagattccca ttggatttat cccactggga gagaccagta 500

 gtttgagtca taccctcttt gccgaaagtg gaaacaaagt ccaacatatt 550

 actgatgcca cacttgccat tgtgaaagga gagacagttc cacttgatgt 600

 cttgcagatc aagggtgaaa aggaacagcc tgtatttgca atgaccggcc 650

 ttcgatgggg atctttcaga gatgctggcg tcaaagttag caagtactgg 700

 tatcttgggc ctctaaaaat caaagcagcc cactttttca gcactcttaa 750

 ggagtggcct cagactcatc aagcctctat ctcatacacg ggacctacag 800

 agagacctcc caatgaacca gaggagaccc ctgtacaaag gccttctttg 850

 tacaggagaa tattacgaag gcttgcgtcc tactgggcac aaccacagga 900

 tgccctttcc caagaggtga gcccggaggt ctggaaagat gtgcagctgt 950

 ccaccattga actgtccatc acaacacgga ataatcagct tgacccgaca 1000

 agcaaagaag attttctgaa tatctgcatt gaacctgaca ccatcagcaa 1050

 aggagacttt ataactatag gaagtcgaaa ggtgagaaac cccaagctgc 1100

 acgtggaggg cacggagtgt ctccaagcca gccagtgcac tttgcttatc 1150

 ccggagggag cagggggctc ttttagcatt gacagtgagg agtatgaagc 1200

 gatgcctgtg gaggtgaaac tgctccccag gaagctgcag ttcttctgtg 1250

 atcctaggaa gagagaacag atgctcacaa gccccaccca gtgagcagca 1300

 gaagacaagc actctgagac cacactttag gccaccggtg ggaccaaaag 1350

 ggaacaggtg cctcagccat cccaacagtg tcgtcagagg gtccccaggg 1400

 cattttcatg gcaagtaccc ctctgccccc actccagcag tgcttcccaa 1450

 agtgtgctct gtcacctgct ttgcaatcgg cttccattag cgcatgtttt 1500

 attttggtgt gacggttggc cctcctaaac acggactttc ctcaggctgg 1550

 ttcaagacgg aaaaggactt tcttctgttt tcttccaaag tgcaaccaca 1600

 gtggagagcc cacggtgggc ttagcctgcc taggcccttc catttctctt 1650

 ctttgaccgt gctaggaatt ccaggaaagt gcattcctgc cctggtgacc 1700

 ttttcctatg tctaggctcc tccacaggtg ctgctatttt gtgagctccg 1750

 gctcctgttt agcttttatt tcagttctaa cctcagtcca gaaacatatg 1800

 tgaggttgtt tccctcttca gccacggcta caataccgga aaatgctagt 1850

 ttttatttat ttttttaagt agtgcttcct aaatggtttg catgagagcc 1900

 acctggggta catgttgaaa acttatttgg ggtctacccc aaacctaata 1950

 acccaaattt ggggatgggg cccaggaata tgcattttta aaaagtcatc 2000

 tgcccttccc aggtgattct gtaagttgtc cctcaactgt acttggagaa 2050

 atcgtgtttt aaagcagtag tccacaaagt attctgctca tgtgccccca 2100

 aaagtatttt gaaaaatcat gtataccctc acccatctaa gttgatatct 2150

 aaaattttat ctaagttggt atctaaaatt tttcatggga agttaaatag 2200

 ttgacaaagt atgtatttgc tggtgtcgtg taaatattgg tattttaaaa 2250

 taaaaactgt tacatcacta ttttaaacat atccagtaca atttaaatat 2300

 cacaacaatt tgacaccctt cattcattta taaaaataaa tgagctagtt 2350

 ctttagtagt taaacatttc aaattggctt ttctccttct gtatttccat 2400

 accacttttc agccaagaat cctatcataa tgtaatctat tatgcccgac 2450

 atcttttaat cattcacccc attacttctt gtcaacaaaa aatataaatg 2500

 gaaatttttt ttttagctct tgctttaagt gtttgtttgt tatctcagtc 2550

 cagaaccaat attatcgtaa ttaattattg gtatataatg aaaacggtat 2600

 taattcttgg atgattaaaa gtttttttat tagaatgttc tttatcctaa 2650

 ttagttcatt tatccaagaa tacatgaatg tgatttacag ctgagatggg 2700

 gttcaacctc agctgtattc cttgtttctg tatagatgta agcacataaa 2750

 ttcgatggaa tagaattacg ttaacaatga aaaaaaaaaa aaaa 2794

<210> 3694
<211> 422
<212> PRT
<213> Homo sapien

<400> 3694
 Met Thr Val Phe Phe Lys Thr Leu Arg Asn His Trp Lys Lys Thr
   1               5                  10                  15

 Thr Ala Gly Leu Cys Leu Leu Thr Trp Gly Gly His Trp Leu Tyr
                  20                  25                  30

 Gly Lys His Cys Asp Asn Leu Leu Arg Arg Ala Ala Cys Gln Glu
                  35                  40                  45

 Ala Gln Val Phe Gly Asn Gln Leu Ile Pro Pro Asn Ala Gln Val
                  50                  55                  60

 Lys Lys Ala Thr Val Phe Leu Asn Pro Ala Ala Cys Lys Gly Lys
                  65                  70                  75

 Ala Arg Thr Leu Phe Glu Lys Asn Ala Ala Pro Ile Leu His Leu
                  80                  85                  90

 Ser Gly Met Asp Val Thr Ile Val Lys Thr Asp Tyr Glu Gly Gln
                  95                 100                 105

 Ala Lys Lys Leu Leu Glu Leu Met Glu Asn Thr Asp Val Ile Ile
                 110                 115                 120

 Val Ala Gly Gly Asp Gly Thr Leu Gln Glu Val Val Thr Gly Val
                 125                 130                 135

 Leu Arg Arg Thr Asp Glu Ala Thr Phe Ser Lys Ile Pro Ile Gly
                 140                 145                 150

 Phe Ile Pro Leu Gly Glu Thr Ser Ser Leu Ser His Thr Leu Phe
                 155                 160                 165

 Ala Glu Ser Gly Asn Lys Val Gln His Ile Thr Asp Ala Thr Leu
                 170                 175                 180

 Ala Ile Val Lys Gly Glu Thr Val Pro Leu Asp Val Leu Gln Ile
                 185                 190                 195

 Lys Gly Glu Lys Glu Gln Pro Val Phe Ala Met Thr Gly Leu Arg
                 200                 205                 210

 Trp Gly Ser Phe Arg Asp Ala Gly Val Lys Val Ser Lys Tyr Trp
                 215                 220                 225

 Tyr Leu Gly Pro Leu Lys Ile Lys Ala Ala His Phe Phe Ser Thr
                 230                 235                 240

 Leu Lys Glu Trp Pro Gln Thr His Gln Ala Ser Ile Ser Tyr Thr
                 245                 250                 255

 Gly Pro Thr Glu Arg Pro Pro Asn Glu Pro Glu Glu Thr Pro Val
                 260                 265                 270

 Gln Arg Pro Ser Leu Tyr Arg Arg Ile Leu Arg Arg Leu Ala Ser
                 275                 280                 285

 Tyr Trp Ala Gln Pro Gln Asp Ala Leu Ser Gln Glu Val Ser Pro
                 290                 295                 300

 Glu Val Trp Lys Asp Val Gln Leu Ser Thr Ile Glu Leu Ser Ile
                 305                 310                 315

 Thr Thr Arg Asn Asn Gln Leu Asp Pro Thr Ser Lys Glu Asp Phe
                 320                 325                 330

 Leu Asn Ile Cys Ile Glu Pro Asp Thr Ile Ser Lys Gly Asp Phe
                 335                 340                 345

 Ile Thr Ile Gly Ser Arg Lys Val Arg Asn Pro Lys Leu His Val
                 350                 355                 360

 Glu Gly Thr Glu Cys Leu Gln Ala Ser Gln Cys Thr Leu Leu Ile
                 365                 370                 375

 Pro Glu Gly Ala Gly Gly Ser Phe Ser Ile Asp Ser Glu Glu Tyr
                 380                 385                 390

 Glu Ala Met Pro Val Glu Val Lys Leu Leu Pro Arg Lys Leu Gln
                 395                 400                 405

 Phe Phe Cys Asp Pro Arg Lys Arg Glu Gln Met Leu Thr Ser Pro
                 410                 415                 420

 Thr Gln


<210> 3695
<211> 4520
<212> DNA
<213> Homo sapien

<400> 3695
 atctttgaag aggcactagc atcagacctc aaggcttttg tcccaccaaa 50

 gatagtgggg gagtttttga acccttgtgg gagcctggtc caggtgaatt 100

 gtgttcctcc ccattggaat gcaaaaatag gctgactcat tggagctagc 150

 ctgaagcaga aaaaggcacc ttttaagtcc aaacaggaaa accaggcagc 200

 atgagcagga atgtggctcg tcattgtata cgggttcaaa aactccccca 250

 ctatctttga agaggcacta gcatcagacc tcaaggcttt tgtcccacca 300

 aatgacaagt gtgtattgtt acaatacatt ggtgatcttt tgtttgcggc 350

 acctaccgag gaagattgct tccagggcac caaagatctc cttcgccttc 400

 tatggaaggc aggttacaag atgtctaagg aaaaagctca ggtctgtgca 450

 aaaagagtaa gatatctagg tttcctagta gcccaagggc agcgtgaact 500

 cggcagtggg cagaaggaag ccatatgtgc gctccccact cctgtcaccc 550

 ggcgacaagt aagggagttt ttaggggcag caggcttttg ctgtacttca 600

 atgccaaact tttcactcac ggcaaagcca ttgtatgaag ccacaaagtg 650

 ggggagaaaa agagcccctc ctctggggta atgagcagaa gaaggccttt 700

 aatgagatca aaaaggcctt aagccaagct cgagccctgg gattgccaga 750

 cctgactaag cctttctttt tctatgtcca tgaaagaaaa ggaatgacta 800

 caggagtttc agttcaaaca gtaggatcat ggtattgacc agtagcctat 850

 ttatcaaagc ggttagacct tgtggccctg ggtggccccc ctgcttaaaa 900

 gcattagctg ccactgccat gctggcagaa aatgctggaa gctgacacta 950

 ggacaaaagc taataatacg ggtgccacac acagtgatca ccttaatgga 1000

 gcaaagagga tatatcactg gctatctaat ccaagaatgt taagatatca 1050

 ggggctctta tgtggaaatc catacgtaac tttaaaaacc gcgaataccc 1100

 tcaacccggc taccctgttg cctgtagaaa tgccgaagtt gcaagaccgg 1150

 tttccccaac gctattgcgt agacgtagta gatgaggtgt tctcaagccg 1200

 gaaagactta agagaccaac cctttaagga cccagacgct gaatatttca 1250

 cagagggaag caggtttgta tcagaagggg tctgcagagc cgggtatgca 1300

 gggtgactct aaattcagta gccaaggcac aggccctccc taccaggacc 1350

 tcagcacaaa aagcagaata gctctaaata gagcactact agtagccaaa 1400

 ggaaggacag ttaacatcta tactgattca aagtatgctt ttgctacatt 1450

 acatgcccat ggagccattt acaaagaaag gggactctta actgctggag 1500

 ggaaagaaat taaagaagaa atcttacaac tcttagaagc tgtgtgggcc 1550

 ccagacaagg tggccgttat tcactgtaaa ggacatcaga caagaggcgg 1600

 catagaagca aaaggaaata ggaaggcaga cagagaagcc agacaagcag 1650

 ctatgtccaa ctcaagtact aaaaagaaaa ccccaaccct gctgcttcta 1700

 ctagaacctt ccttacctga aaccccaagc tactctccca atgaaaaagc 1750

 ttggtttgaa caagagagcg gaagttacat acaaggaggc aggtggaagt 1800

 tctcagatgg gaggctagct attccggaag caatagcccc ccaatttatg 1850

 aagcagtttc atcagggaac acacatggga aagactgcat tagaaactct 1900

 tgtaggatgg catttctatg tgccatgcct tactgccatc actcgagccg 1950

 tttgtgagca atgtttaacc tgcgcccaga acaatccatg gcaagtgcca 2000

 actcagcccc cagggattca agagaccgga gctacaccct gtgaaaactt 2050

 gcttgtggac tttaccgaac tgccccgagc acggggttat cagtacatgc 2100

 tagtgtttgt ttgcactttc tcagggtggg tcgaggcatt ccctaccagg 2150

 atagagaaag cccaagaagt aaccagactg ttgctaaaag acattattcc 2200

 taggtttgga ctgcctctaa ctttaggatc agataatggc ccagcattca 2250

 tggctgaagt agttcagcag ctgtcgcagc tgctaaagat aaagtggaaa 2300

 ctgcacatag tctaccaccc acagagctca ggaaaggtac aatggatgaa 2350

 ccagacacta aaacatctgc tgaagttttg tcaagaacct catcttaggt 2400

 gggatcaggt cttgcccatg gcctttctcc aagtcaggtg tacccttacc 2450

 aaattgactg ggctttcacc ctgtgaaatt gtgttcggcc gaccaccccc 2500

 gattataaat caggtaaaag gtgatctgtg ggaactaggg gaactaactt 2550

 taaaaaggca aatgcaagct ttaggattag ctatgcaaaa gattcatggc 2600

 tgggtacgag aaaaattgcc tataagccta acagacccag ttcacccctt 2650

 tacacctggg gacttggttt gggttaagaa atggaaccca accacactag 2700

 ggcccatatg ggatgggccc acactgtaat cttgtctact cccactgctg 2750

 ttaaagttgc aggtatcaca ccttggattc atcacagtcg actgaagctg 2800

 gctgcgcagg accagtgaac cagtcaacaa gactcagacc atccaacatg 2850

 actaatcctg tggcaaaacc acgacaccac tgagaaagtc aaccaccctg 2900

 ctgtgatcac tctggaggct ggtcagtcta cgcacaactg aagcttgaga 2950

 agtcaaaccc tgctgtagtc acacactgga agctgactag tctacgcatg 3000

 gccaaagctt gaggagtctt cactagataa gtaaatgtgg atagaactta 3050

 taagcctagt agtgatctta gtaatactga ttatcttatt attatgttac 3100

 tgtttttgtt caggaaaagg cctatattgg atctgtggag cacaggcata 3150

 tcagcaactg ccagctaaat ggacaagagc atgtgtatta ggaacaatca 3200

 agccatcctt ctttctaatt cctctaaagc aaggggaact cttaggataa 3250

 ccagtctata atgagaataa aagaactaaa aggagcatga tctcaaaaat 3300

 aaatataaat atcaaaaaag acatagacat aggagactag aaaaataatc 3350

 aatggcctcc tgaaaaaatc attaaatagt atgggccagc tacctaggca 3400

 caaaataggt aatggggata ccacacccca atttatatgc tcaactgtat 3450

 cataaggtta caggctgttc ttgaaataat aacctatgaa acatcaagag 3500

 ctttttgatg aacctatgaa catcaagatt tactagctgt acaagctaca 3550

 cagataagga atgccatata tcaaaacagg ctggcactag attacctcct 3600

 agcctcagaa ggaggagtat gtgggaagtt taatctaaca aactgctgtt 3650

 tagacgtaga caataggcga gctgtcatgg gaattactgc caggatgtgg 3700

 aagttagccc aagttccagt tcaaacctgg tcaggttggt ctccagattc 3750

 tctctttgaa ggatggtttt caacctttag tgggttcaaa accttaatag 3800

 gtgggttcct gcttatcaca ggtgcctgcc taattcttcc ttgtctccta 3850

 cctcttctca tcagaagtgt tcagtcaact atagaggcag ttgtggccaa 3900

 atacactact actcaaataa tggcattgac taagtattgc cccaagaata 3950

 atatgtaccg actcaagaaa aaataaacaa ctgtggtgct attaaccaac 4000

 atttatatag agcaccaaag gggggaatga agtggaaaat taaaatagga 4050

 taatagcata agtaataata gtaaaattat agtaacagaa ataatagctc 4100

 atagaatgaa ttgctgtacc aaccaaggct aaaaagaatt taagtagccc 4150

 ccctgaagtt agagttaaag aaggatatta actgccagtc ccaagaaaca 4200

 ttaaccatat ctgcccttca ggtattttgt aggctctgta agctcgtgtt 4250

 ttcttccctc cttgtacagc tgcaaggtca caagacagat aagcataagc 4300

 tgcatactaa gttttcccag agatgtaaga catgttgcaa aagtgtcaca 4350

 agataattaa tggactttgt tcttgcttct gtaagcctgc ttcctgcttc 4400

 acgtaattcc tgcctcaaaa tgcttaaaag acattcgttt tctttgatct 4450

 atgcttagat tttctggatg caattccact gagccgatgt acacctaaaa 4500

 ataaaaactt tcctgcatcc 4520

<210> 3696
<211> 505
<212> PRT
<213> Homo sapien

<400> 3696
 Glu Thr Asn Pro Leu Arg Thr Gln Thr Leu Asn Ile Ser Gln Arg
   1               5                  10                  15

 Glu Ala Gly Leu Tyr Gln Lys Gly Ser Ala Glu Pro Gly Met Gln
                  20                  25                  30

 Gly Asp Ser Lys Phe Ser Ser Gln Gly Thr Gly Pro Pro Tyr Gln
                  35                  40                  45

 Asp Leu Ser Thr Lys Ser Arg Ile Ala Leu Asn Arg Ala Leu Leu
                  50                  55                  60

 Val Ala Lys Gly Arg Thr Val Asn Ile Tyr Thr Asp Ser Lys Tyr
                  65                  70                  75

 Ala Phe Ala Thr Leu His Ala His Gly Ala Ile Tyr Lys Glu Arg
                  80                  85                  90

 Gly Leu Leu Thr Ala Gly Gly Lys Glu Ile Lys Glu Glu Ile Leu
                  95                 100                 105

 Gln Leu Leu Glu Ala Val Trp Ala Pro Asp Lys Val Ala Val Ile
                 110                 115                 120

 His Cys Lys Gly His Gln Thr Arg Gly Gly Ile Glu Ala Lys Gly
                 125                 130                 135

 Asn Arg Lys Ala Asp Arg Glu Ala Arg Gln Ala Ala Met Ser Asn
                 140                 145                 150

 Ser Ser Thr Lys Lys Lys Thr Pro Thr Leu Leu Leu Leu Leu Glu
                 155                 160                 165

 Pro Ser Leu Pro Glu Thr Pro Ser Tyr Ser Pro Asn Glu Lys Ala
                 170                 175                 180

 Trp Phe Glu Gln Glu Ser Gly Ser Tyr Ile Gln Gly Gly Arg Trp
                 185                 190                 195

 Lys Phe Ser Asp Gly Arg Leu Ala Ile Pro Glu Ala Ile Ala Pro
                 200                 205                 210

 Gln Phe Met Lys Gln Phe His Gln Gly Thr His Met Gly Lys Thr
                 215                 220                 225

 Ala Leu Glu Thr Leu Val Gly Trp His Phe Tyr Val Pro Cys Leu
                 230                 235                 240

 Thr Ala Ile Thr Arg Ala Val Cys Glu Gln Cys Leu Thr Cys Ala
                 245                 250                 255

 Gln Asn Asn Pro Trp Gln Val Pro Thr Gln Pro Pro Gly Ile Gln
                 260                 265                 270

 Glu Thr Gly Ala Thr Pro Cys Glu Asn Leu Leu Val Asp Phe Thr
                 275                 280                 285

 Glu Leu Pro Arg Ala Arg Gly Tyr Gln Tyr Met Leu Val Phe Val
                 290                 295                 300

 Cys Thr Phe Ser Gly Trp Val Glu Ala Phe Pro Thr Arg Ile Glu
                 305                 310                 315

 Lys Ala Gln Glu Val Thr Arg Leu Leu Leu Lys Asp Ile Ile Pro
                 320                 325                 330

 Arg Phe Gly Leu Pro Leu Thr Leu Gly Ser Asp Asn Gly Pro Ala
                 335                 340                 345

 Phe Met Ala Glu Val Val Gln Gln Leu Ser Gln Leu Leu Lys Ile
                 350                 355                 360

 Lys Trp Lys Leu His Ile Val Tyr His Pro Gln Ser Ser Gly Lys
                 365                 370                 375

 Val Gln Trp Met Asn Gln Thr Leu Lys His Leu Leu Lys Phe Cys
                 380                 385                 390

 Gln Glu Pro His Leu Arg Trp Asp Gln Val Leu Pro Met Ala Phe
                 395                 400                 405

 Leu Gln Val Arg Cys Thr Leu Thr Lys Leu Thr Gly Leu Ser Pro
                 410                 415                 420

 Cys Glu Ile Val Phe Gly Arg Pro Pro Pro Ile Ile Asn Gln Val
                 425                 430                 435

 Lys Gly Asp Leu Trp Glu Leu Gly Glu Leu Thr Leu Lys Arg Gln
                 440                 445                 450

 Met Gln Ala Leu Gly Leu Ala Met Gln Lys Ile His Gly Trp Val
                 455                 460                 465

 Arg Glu Lys Leu Pro Ile Ser Leu Thr Asp Pro Val His Pro Phe
                 470                 475                 480

 Thr Pro Gly Asp Leu Val Trp Val Lys Lys Trp Asn Pro Thr Thr
                 485                 490                 495

 Leu Gly Pro Ile Trp Asp Gly Pro Thr Leu
                 500                 505

<210> 3697
<211> 3474
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 541
<223> Unknown base

<400> 3697
 gatcattcta gctatcccag aagccttttg gaaaaagccc cacatgtctt 50

 ctttctttgg tgttcaagct gaccttccta cctctttgcc attgataatt 100

 aggggcagaa ttaagtattg taagttgtta ttctaagttt aaatagcttc 150

 ctgtggtttt tagaacaagc aggatatctt tggagatgca aaaagctctt 200

 gaattggatc tgtctttgtg agatccttat gaacaatata acctgataac 250

 ttgagaatca gaaaaacact gcatcttctg gataagttaa ccattgttag 300

 ttttctgtag ctactgatgt tcatttgtac tatatgttgc ctttcagaat 350

 gtggtaattg taatctttaa cattttcatg taaaacatat ttcctgatca 400

 tctttccatt gtcttcatgg aaaattgata aatatttgtg ccttccaact 450

 ctcgtcttgg ttgaatgact tcatcttaat acaagcattt tgatttcctt 500

 tctttttaca gcatggacac cacgttgctg aaaacatgct ntgggactgc 550

 cactgaattt atcttttgcg gttttatgac aaagttatta gtagtttccc 600

 ttttttgaat tagtattttc gaagttaata tcacaatgag ttcaggctta 650

 tggagccaag aaaaagtcac ttcaccctac tgggaagagc ggatttttta 700

 cttgcttctt caagaatgca gcgttacaga caaacaaaca caaaagctcc 750

 ttaaagtacc gaagggaagt ataggacagt atattcaaga tcgttctgtg 800

 gggcattcaa ggattccttc tgcaaaaggc aagaaaaatc agatcggatt 850

 acaacattct agagcaagct catgcagttc tcttggtgat gacaaggatg 900

 tcgtagagat aaatgaaaag ttcacagagt tacttttggc aattaccaat 950

 tgtgaggaga ggtcagcctg tttaaaaaca gaaacagact aagtaaaggc 1000

 ctccaaatag acgtgggctg tcctgtgaaa gtacagctga gatctgggga 1050

 agaaaaattt cctggagttg tacgcttcag aggacccctg ttagcagaga 1100

 ggacagtctc cggaatattc tttggagttg aattgctgga agaaggtcgt 1150

 ggtcaaggtt tcactgacgg ggtgtaccaa gggaaacagc tttttcagtg 1200

 tgatgaagat tgtggcgtgt ttgttgcatt ggacaagcta gaactcatag 1250

 aagatgatga cactgcattg gaaagtgatt acgcaggtcc tggggacaca 1300

 atgcaggtcg aacttcctcc tttggaaata aactccagag tttctttgaa 1350

 ggttggagaa acaatagaat ctggaacagt tatattctgt gatgttttgc 1400

 caggaaaaga aagcttagga tattttgttg gtgtggacat ggataaccct 1450

 attggcaact gggatggaag atttgatgga gtgcagcttt gtagttttgc 1500

 gtgtgttgaa agtacaattc tattgcacat caatgatatc atcccagaga 1550

 gtgtgacgca ggaaaggagg cctcccaaac ttgcctttat gtcaagaggt 1600

 gttggggaca aaggttcatc cagtcataat aaaccaaagg ctacaggatc 1650

 tacctcagac cctggaaata gaaacagatc tgaattattt tataccttaa 1700

 atgggtcttc tgttgactca caaccacaat ccaaatcaaa aaatacatgg 1750

 tacattgatg aagttgcaga agaccctgca aaatctctta cagagatatc 1800

 tacagacttt gaccgttctt caccaccact ccagcctcct cctgtgaact 1850

 cactgaccac cgagaacaga ttccactctt taccattcag tctcaccaag 1900

 atgcccaata ccaatggaag tattggccac agtccacttt ctctgtcagc 1950

 ccagtctgta atggaagagc taaacactgc acccgtccaa gagagtccac 2000

 ccttggccat gcctcctggg aactcacatg gtctagaagt gggctcattg 2050

 gctgaagtta aggagaaccc tcctttctat ggggtaatcc gttggatcgg 2100

 tcagccacca ggactgaatg aagtgctcgc tggactggaa ctggaagatg 2150

 agtgtgcagg ctgtacggat ggaaccttca gaggcactcg gtatttcacc 2200

 tgtgccctga agaaggcgct gtttgtgaaa ctgaagagct gcaggcctga 2250

 ctctaggttt gcatcattgc agccggtttc caatcagatt gagcgctgta 2300

 actctttagc atttggaggc tacttaagtg aagtagtaga agaaaatact 2350

 ccaccaaaaa tggaaaaaga aggcttggag ataatgattg ggaagaagaa 2400

 aggcatccag ggtcattaca attcttgtta cttagactca accttattct 2450

 gcttatttgc ttttagttct gttctggaca ctgtgttact tagacccaaa 2500

 gaaaagaacg atgtagaata ttatagtgaa acccaagagc tactgaggac 2550

 agaaattgtt aatcctctga gaatatatgg atatgtgtgt gccacaaaaa 2600

 ttatgaaact gaggaaaata cttgaaaagg tggaggctgc atcaggattt 2650

 acctctgaag aaaaaggtga ccatcttaac ttatatgcgt taaaaataac 2700

 tgaagagcat attcacatgt caaagtatta gctgaaatgt gtgtctgtgt 2750

 agttgggggg ttttctttta aattagaaat ttctttttat gtgatatatg 2800

 gttagctcct ctttttgtaa attcttcctc tcttctaaaa gtgattgatg 2850

 atgtggaata atgaactcct ttaagaagct ggctggttct agtatattaa 2900

 atgcttaaat aaaaagtcct ttcctttcca cctagcaatg atattctcag 2950

 ttgtttctct cttgtggtgc agagttgcat tgggttttct acattttccc 3000

 actgagtctt ccctgttgta aaagggagtt agaaagctgc taactaggat 3050

 taagtttata gtcagggaac agtgttataa tctcttccta gctaatgggc 3100

 ttactcaaag attcaccacc tgactttgaa tttgtcagca gcatactgta 3150

 aacagctgta atgttcagag gcttgcagga aaaaacagag catacttcag 3200

 attgtactcc atttacctta acccctccaa aggaaataac agctatttca 3250

 ttatgtgcaa tgtgttacac cctttcaaat gtaataaact cacaacaaaa 3300

 ttgaaacata atacttgatt ataacttatt aaatgtcttt tatgtttttc 3350

 ctttgtcagg aaaacttgaa aactgtgctt ttaattgaaa taatattgga 3400

 tgaatgaaac tgaattcagt attaaaattt gactgttaga aatgaaaaat 3450

 aaaatgattt aaaaatttaa aaaa 3474

<210> 3698
<211> 698
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 541
<223> Unknown amino acid

<400> 3698
 Met Ser Ser Gly Leu Trp Ser Gln Glu Lys Val Thr Ser Pro Tyr
   1               5                  10                  15

 Trp Glu Glu Arg Ile Phe Tyr Leu Leu Leu Gln Glu Cys Ser Val
                  20                  25                  30

 Thr Asp Lys Gln Thr Gln Lys Leu Leu Lys Val Pro Lys Gly Ser
                  35                  40                  45

 Ile Gly Gln Tyr Ile Gln Asp Arg Ser Val Gly His Ser Arg Ile
                  50                  55                  60

 Pro Ser Ala Lys Gly Lys Lys Asn Gln Ile Gly Leu Gln His Ser
                  65                  70                  75

 Arg Ala Ser Ser Cys Ser Ser Leu Gly Asp Asp Lys Asp Val Val
                  80                  85                  90

 Glu Ile Asn Glu Lys Phe Thr Glu Leu Leu Leu Ala Ile Thr Asn
                  95                 100                 105

 Cys Glu Gly Glu Val Ser Leu Phe Lys Asn Arg Asn Arg Leu Ser
                 110                 115                 120

 Lys Gly Leu Gln Ile Asp Val Gly Cys Pro Val Lys Val Gln Leu
                 125                 130                 135

 Arg Ser Gly Glu Glu Lys Phe Pro Gly Val Val Arg Phe Arg Gly
                 140                 145                 150

 Pro Leu Leu Ala Glu Arg Thr Val Ser Gly Ile Phe Phe Gly Val
                 155                 160                 165

 Glu Leu Leu Glu Glu Gly Arg Gly Gln Gly Phe Thr Asp Gly Val
                 170                 175                 180

 Tyr Gln Gly Lys Gln Leu Phe Gln Cys Asp Glu Asp Cys Gly Val
                 185                 190                 195

 Phe Val Ala Leu Asp Lys Leu Glu Leu Ile Glu Asp Asp Asp Thr
                 200                 205                 210

 Ala Leu Glu Ser Asp Tyr Ala Gly Pro Gly Asp Thr Met Gln Val
                 215                 220                 225

 Glu Leu Pro Pro Leu Glu Ile Asn Ser Arg Val Ser Leu Lys Val
                 230                 235                 240

 Gly Glu Thr Ile Glu Ser Gly Thr Val Ile Phe Cys Asp Val Leu
                 245                 250                 255

 Pro Gly Lys Glu Ser Leu Gly Tyr Phe Val Gly Val Asp Met Asp
                 260                 265                 270

 Asn Pro Ile Gly Asn Trp Asp Gly Arg Phe Asp Gly Val Gln Leu
                 275                 280                 285

 Cys Ser Phe Ala Cys Val Glu Ser Thr Ile Leu Leu His Ile Asn
                 290                 295                 300

 Asp Ile Ile Pro Glu Ser Val Thr Gln Glu Arg Arg Pro Pro Lys
                 305                 310                 315

 Leu Ala Phe Met Ser Arg Gly Val Gly Asp Lys Gly Ser Ser Ser
                 320                 325                 330

 His Asn Lys Pro Lys Ala Thr Gly Ser Thr Ser Asp Pro Gly Asn
                 335                 340                 345

 Arg Asn Arg Ser Glu Leu Phe Tyr Thr Leu Asn Gly Ser Ser Val
                 350                 355                 360

 Asp Ser Gln Pro Gln Ser Lys Ser Lys Asn Thr Trp Tyr Ile Asp
                 365                 370                 375

 Glu Val Ala Glu Asp Pro Ala Lys Ser Leu Thr Glu Ile Ser Thr
                 380                 385                 390

 Asp Phe Asp Arg Ser Ser Pro Pro Leu Gln Pro Pro Pro Val Asn
                 395                 400                 405

 Ser Leu Thr Thr Glu Asn Arg Phe His Ser Leu Pro Phe Ser Leu
                 410                 415                 420

 Thr Lys Met Pro Asn Thr Asn Gly Ser Ile Gly His Ser Pro Leu
                 425                 430                 435

 Ser Leu Ser Ala Gln Ser Val Met Glu Glu Leu Asn Thr Ala Pro
                 440                 445                 450

 Val Gln Glu Ser Pro Pro Leu Ala Met Pro Pro Gly Asn Ser His
                 455                 460                 465

 Gly Leu Glu Val Gly Ser Leu Ala Glu Val Lys Glu Asn Pro Pro
                 470                 475                 480

 Phe Tyr Gly Val Ile Arg Trp Ile Gly Gln Pro Pro Gly Leu Asn
                 485                 490                 495

 Glu Val Leu Ala Gly Leu Glu Leu Glu Asp Glu Cys Ala Gly Cys
                 500                 505                 510

 Thr Asp Gly Thr Phe Arg Gly Thr Arg Tyr Phe Thr Cys Ala Leu
                 515                 520                 525

 Lys Lys Ala Leu Phe Val Lys Leu Lys Ser Cys Arg Pro Asp Ser
                 530                 535                 540

 Arg Phe Ala Ser Leu Gln Pro Val Ser Asn Gln Ile Glu Arg Cys
                 545                 550                 555

 Asn Ser Leu Ala Phe Gly Gly Tyr Leu Ser Glu Val Val Glu Glu
                 560                 565                 570

 Asn Thr Pro Pro Lys Met Glu Lys Glu Gly Leu Glu Ile Met Ile
                 575                 580                 585

 Gly Lys Lys Lys Gly Ile Gln Gly His Tyr Asn Ser Cys Tyr Leu
                 590                 595                 600

 Asp Ser Thr Leu Phe Cys Leu Phe Ala Phe Ser Ser Val Leu Asp
                 605                 610                 615

 Thr Val Leu Leu Arg Pro Lys Glu Lys Asn Asp Val Glu Tyr Tyr
                 620                 625                 630

 Ser Glu Thr Gln Glu Leu Leu Arg Thr Glu Ile Val Asn Pro Leu
                 635                 640                 645

 Arg Ile Tyr Gly Tyr Val Cys Ala Thr Lys Ile Met Lys Leu Arg
                 650                 655                 660

 Lys Ile Leu Glu Lys Val Glu Ala Ala Ser Gly Phe Thr Ser Glu
                 665                 670                 675

 Glu Lys Gly Asp His Leu Asn Leu Tyr Ala Leu Lys Ile Thr Glu
                 680                 685                 690

 Glu His Ile His Met Ser Lys Tyr
                 695

<210> 3699
<211> 3907
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 266-400, 2897-3191
<223> Unknown base

<400> 3699
 ggggaccctc gggaagccgc tgcagccccg gatctgctct gtctccttcc 50

 tcctgtgctg caggaggggg tcagctgctc ttcctgaacc tgtttgcacc 100

 tctacagtct tgagagagat cttttaaaaa tcaaaataga acagaacttc 150

 aaaggaataa tcctagaaag ttgtgattat ttcaaagatg ttgctttcac 200

 tgttcaaaat attttatttt taaacttgtt ttaaaaaata ttcttttcag 250

 ggctgagcac agtgannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 tggattgttg aattcaatgc ttgggtcacc tccagattca ttttcacagt 450

 ctttcatgtt ttggtcatat gacattgtat tttgctgcca tatgactgat 500

 ctttttttgt taaatgtgag atacttgtta aaaaatgttt agcaatgaat 550

 tgaggcctag tagcatgtta tcttgctgca gaagagatgg gagtctactt 600

 ctgggggatg gtcaggggtc ctccatacag gctgcaattg aagtcgtcgg 650

 tgcaggctca gtccctacaa aggccagggt atttcctgtc cacctttatt 700

 ctgatgcatg actcttctgg gtctcaacca gagccagtgg acttcagtat 750

 gggtcgcttt cattggcaga ccctcaatcc acttgttttc catctaatcc 800

 cacgcatgtg tgcaaaagct gctgtgcttc tttgcatctc agtagttcct 850

 tctggaattc agcaatgaaa ctcagggaaa tgggttccaa atgcgaggct 900

 gactttcgtc ctgggtttcc ttcttctcca tcttcacctc atgtctgttt 950

 actgccatgt tagcaatttg atgtattcaa tcatgggttt tatattctgt 1000

 ttggtgtccc ccattgttct catcggagat cagaagcttc agatgcactt 1050

 atgtcaactc aagagtagaa tgcttcctta gcttccctcc agagtcaggt 1100

 tttgtgtttc tagttcccaa gtgcacagca ggagtagtga tgtcctcact 1150

 ggcttctcat ttgcattaag ctgtgagctt ctttagcgtg gggacaggac 1200

 cctgctccca ttgcattctc agcaccacac cacacactcc ttgtttgagg 1250

 ccactccaga cagcatgtgc tgaaggatgc cttgtggtca gaaacaagtt 1300

 cattaacttt ctctttgaag tgttttcgcc cctgtttcct agcgttctgg 1350

 gaattttaca catccttcct ataaaaccaa gtatcaggtg agatccttag 1400

 gatcaggacc atgaatcaag tggagtgagg gcaacacagc aaacttaccc 1450

 tttttaggcc gtttcctttt tctgccctca atctctgtga actgaacctt 1500

 gttaaagtca gtcaacacca gggtggatgg tttgccgttg tcacctattt 1550

 tcaggacata acaccctgac ttaggagcca ttccgatcat ttctaattca 1600

 atagatgcgc ccagcattca gattgccttt tctctcaacc aggatcttta 1650

 aagtcgatga caagagttcc agtcctgaat catggcaaag tgcagtagtg 1700

 aactgcgggg ttattctgga aggatctctc tatggctgat ggtctcagtt 1750

 ccggcatcag cctctgactg agaatcaggt ctcacacagg aggagtcaga 1800

 tgaggagcaa tcctctgctt ccgatggagt tagttgtgat gaattggtga 1850

 ggtctggttt ttcacactga actaaaatga gctttcgctg tgtcaagcac 1900

 aagactgacc ccagagacac acatagtgca cctcatagaa gcttttaata 1950

 gtctttatat ttactaaaga ataggactaa ctatggaact atgaagatga 2000

 gctggaaatg acaggtgact tgccagcagg ccagagtgtg actttttttt 2050

 gtccctcaat gggaggtgtc aattctccct tcggttgtga gaatcagttg 2100

 gttcatttgt gggaaggttg caggggggat ctttgaatca cagccttcag 2150

 atgccagaag ggcagaggga atcccacacg ggctggtgga tcatgtgtgt 2200

 gcatttctct cccttctaat ctgaggaaac taagcgtgaa agaatgtgag 2250

 catgcagaaa aggagaggca ggtatcagag gcagaggaaa atgggaaatt 2300

 ggatatgaaa gaaatacaca cctacaagtg agttcagaaa ctgaacccca 2350

 ccctcctggg aaacgcccat tggagtgttg tttttaacct ttgtacagta 2400

 tttagaccca gtaaatgcag aaatagaaac aaacggtcag aagacatatc 2450

 gtgagagaga gcgagagaga gttcacaaaa cagaaaacaa agtaccttaa 2500

 tatttaccag tgaccaaaag atgtgaagta gcaaaacgtc tcctgacccc 2550

 attgccagct agactgtgtg gaaactcggt tcataccagc cattctaggg 2600

 gtggggtgag ttgttgtcat ccttaggaaa gtgtgttgtt gtaggatcaa 2650

 ccacatcctt caaaaggact atgcctgttt ataagcccag ctgtttctgc 2700

 cctgtgaaac acggtaagga tattaataca aagagaatac agctttatga 2750

 taaaagatgc tcaatgaagg atgaattagg gatgtactga gaatggggaa 2800

 ggaaactatc atctcagaag tcagcaggca gtaagcaaga ggaggaatca 2850

 atacagcaac agtttggatc agactgtaca gtttttttgt ttttgtnnnn 2900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3050

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3100

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3150

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngactgtact 3200

 cttctagcca tctgaaatac gttttctagg tagagataga ttgtgtaagg 3250

 gtacagttgt gaggataaca gaaacatggc agattattta aaatcatcct 3300

 gaaagtggtg ctttatctga tgaaagtgat tgtaatccat aggaaaatgt 3350

 ttcaacgtgc gcaagagttg cggcggcgag cagaggacta ccacaaatgc 3400

 aaaatccccc cttctgcaag aaaggctctt tgcaactggg tcagaatggc 3450

 ggcagcggag catcgtcatt cttcaggatt gccctactgg ccctacctca 3500

 cagctgaaac tttaaaaaac aggatgggcc accagccacc tcctccaact 3550

 caacaacatt ctataactga taactccctg agcctcaaga cacctcccga 3600

 gtgtctgctc actccccttc caccctcagc ggatgataat ctcaagacac 3650

 ctcccgagtg tgtgctcact ccccttccac cctcagcgga tgataatctc 3700

 aagacacctc ccgagtgtgt gctcactccc cttccaccct cagcggatga 3750

 taatctcaag acacctcctg agtgtctgct cactcccctt ccaacctcag 3800

 cggatgataa tctcaagaca cctcccgagt gtctgctcac tccccttcca 3850

 ccctcagctc taccctcagc ggatgataat ctcaagaaac taaggaagaa 3900

 taaataa 3907

<210> 3700
<211> 195
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 266-400, 2897-3191
<223> Unknown amino acid

<400> 3700
 Met Lys Val Ile Val Ile His Arg Lys Met Phe Gln Arg Ala Gln
   1               5                  10                  15

 Glu Leu Arg Arg Arg Ala Glu Asp Tyr His Lys Cys Lys Ile Pro
                  20                  25                  30

 Pro Ser Ala Arg Lys Ala Leu Cys Asn Trp Val Arg Met Ala Ala
                  35                  40                  45

 Ala Glu His Arg His Ser Ser Gly Leu Pro Tyr Trp Pro Tyr Leu
                  50                  55                  60

 Thr Ala Glu Thr Leu Lys Asn Arg Met Gly His Gln Pro Pro Pro
                  65                  70                  75

 Pro Thr Gln Gln His Ser Ile Thr Asp Asn Ser Leu Ser Leu Lys
                  80                  85                  90

 Thr Pro Pro Glu Cys Leu Leu Thr Pro Leu Pro Pro Ser Ala Asp
                  95                 100                 105

 Asp Asn Leu Lys Thr Pro Pro Glu Cys Val Leu Thr Pro Leu Pro
                 110                 115                 120

 Pro Ser Ala Asp Asp Asn Leu Lys Thr Pro Pro Glu Cys Val Leu
                 125                 130                 135

 Thr Pro Leu Pro Pro Ser Ala Asp Asp Asn Leu Lys Thr Pro Pro
                 140                 145                 150

 Glu Cys Leu Leu Thr Pro Leu Pro Thr Ser Ala Asp Asp Asn Leu
                 155                 160                 165

 Lys Thr Pro Pro Glu Cys Leu Leu Thr Pro Leu Pro Pro Ser Ala
                 170                 175                 180

 Leu Pro Ser Ala Asp Asp Asn Leu Lys Lys Leu Arg Lys Asn Lys
                 185                 190                 195

<210> 3701
<211> 1236
<212> DNA
<213> Homo sapien

<400> 3701
 ataatcttca ttcctgggtt ctccacttca atagtcgtgg cagtgctgct 50

 gaatttgcag tttttcacat catgaccagg attctggaag ctacaaacag 100

 tttgttttta cctctgcctc ctggttttca tactctgcac accatcctcg 150

 gggtccagtg tctccctttg cataacctgc tgcattgcat tgacagtgga 200

 gtgttgcttc tcactgaaac agctgtcata aggctcatga aagatctgga 250

 taatacagag aaaaatgaaa aactgaaatt cagtatcatt gtgcggcttc 300

 ctccgcttat tgggcagaag atttgtagac tttgggatca tcctatgagt 350

 tctaacatca tttcgcggaa ccacgtgacg cgactgcttc agaactataa 400

 gaaacagcct cggaattcta tgattaacaa gtcatcgttc agtgtagaat 450

 ttctgcctct gaactacttc attgaaattc tgacagatat agagtcctcc 500

 aatcaagccc tgtatccttt tgaaggacat gacaatgtgg atgcagaatt 550

 tgtagaggaa gcagctctga aacacaccgc gatgctttta ggcttatgaa 600

 aaagaaaacg caattggatc tgctgctgcc attttaatct tgctcattaa 650

 ccttactcct ctgagaattc tttaacaata tttaaaattg gtaacaaaaa 700

 tagtttagcc ataattgttt agccatgtga gtttcaggtt ggtacacgtt 750

 cagacagaac tgctgtatca cattccaatt ttgaatagcc agtgagcaat 800

 caagtgtaga gaaatgataa atggcctaag aaggcataca gtggcataaa 850

 cgatgctctt cctagtagct taataggccc acaagctagt ttctgttgca 900

 ctctgaaata aaatatgctt taaaaatgta gggaacagtg cttagaaaag 950

 caaaaactag gtgtgtcatt gaaataatag gcataaaaat taaatgttac 1000

 ataagaacac tatttggaaa gagggtcctt ttaaaaactg aatttgtact 1050

 aaatcagatt tgccatgtcc agtacagaat aatttgtact tagtatttgc 1100

 agcagggttt gtctttgtga attcagatga aacatattta ttttttttta 1150

 tttataaaag gttgatttag gaatattttg tcagtcatta aaaaacctga 1200

 aaacataaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 1236

<210> 3702
<211> 1853
<212> DNA
<213> Homo sapien

<400> 3702
 ggcacgaggg tccctgggcc ggacggcggt gtcccggcgt ggcgggaagc 50

 cggcactgga gcgggagcgc actgggcgcg ggaccgggag gcgcagggac 100

 cggacggctc ccgagtcgcc cacctgacgc tagaagaagt cttcacttcc 150

 caggagagcc aaagcgtgtc tggccctagg tgggaaaaga actggctgtg 200

 acctttgccc tgacctggaa gggcccagcc ttgggctgaa tggcagcacc 250

 cacgcccgcc cgtccggtgc tgacccacct gctggtggct ctcttcggca 300

 tgggctcctg ggctgcggtc aatgggatct gggtggagct acctgtggtg 350

 gtcaaagagc ttccagaggg ttggagcctc ccctcttacg tctctgtgct 400

 tgtggctctg gggaacctgg gtctgctggt ggtgaccctc tggaggaggc 450

 tggccccagg aaaggacgag caggtcccca tccgggtggt gcaggtgctg 500

 ggcatggtgg gcacagccct gctggcctct ctgtggcacc atgtggcccc 550

 agtggcagga cagttgcatt ctgtggcctt cttagcactg gcctttgtgc 600

 tggcactggc atgctgtgcc tcgaatgtca ctttcctgcc cttcttgagc 650

 cacctgccac ctcgcttctt acggtcattc ttcctgggtc aaggcctgag 700

 tgccctgctg ccctgcgtgc tggccctagt gcagggtgtg ggccgcctcg 750

 agtgcccgcc agcccccatc aacggcaccc ctggcccccc gctcgacttc 800

 cttgagcgtt ttcccgccag caccttcttc tgggcactga ctgcccttct 850

 ggtcgcttca gctgctgcct tccagggtct tctgctgctg ttgccgccac 900

 caccatctgt acccacaggg gagttaggat caggcctcca ggtgggagcc 950

 ccaggagcag aggaagaggt ggaagagtcc tcaccactgc aagagccacc 1000

 aagccaggca gcaggcacca cccctggtcc agaccctaag gcctatcagc 1050

 ttctatcagc ccgcagtgcc tgcctgctgg gcctgttggc cgccaccaac 1100

 gcgctgacca atggcgtgct gcctgccgtg cagagctttt cctgcttacc 1150

 ctacgggcgt ctggcctacc acctggctgt ggtgctgggc agtgctgcca 1200

 atcccctggc ctgcttcctg gccatgggtg tgctgtgcag gtccttggca 1250

 gggctgggcg gcctctctct gctgggcgtg ttctgtgggg gctacctgat 1300

 ggcgctggca gtcctgagcc cctgcccgcc cctggtgggc acctcggcgg 1350

 gggtggtcct cgtggtgctg tcgtgggtgc tgtgtcttgg cgtgttctcc 1400

 tacgtgaagg tggcagccag ctccctgctg catggcgggg gccggccggc 1450

 attgctggca gccggcgtgg ccatccaggt gggctctctg ctcggcgctg 1500

 ttgctatgtt ccccccgacc agcatctatc acgtgttcca cagcagaaag 1550

 gactgtgcag acccctgtga ctcctgagcc tgggcaggtg gggaccccgc 1600

 tccccaacac ctgtctttcc ctcaatgctg ccaccatgcc tgagtgcctg 1650

 cagcccagga ggcccgcaca ccggtacact cgtggacacc tacacactcc 1700

 ataggagatc ctggctttcc agggtgggca agggcaagga gcaggcttgg 1750

 agccagggac cagtgggggc tgtagggtaa gcccctgagc ctgggaccta 1800

 catgtggttt gcgtaataaa acatttgtat ttaaaaaaaa aaaaaaaaaa 1850

 aaa 1853

<210> 3703
<211> 445
<212> PRT
<213> Homo sapien

<400> 3703
 Met Ala Ala Pro Thr Pro Ala Arg Pro Val Leu Thr His Leu Leu
   1               5                  10                  15

 Val Ala Leu Phe Gly Met Gly Ser Trp Ala Ala Val Asn Gly Ile
                  20                  25                  30

 Trp Val Glu Leu Pro Val Val Val Lys Glu Leu Pro Glu Gly Trp
                  35                  40                  45

 Ser Leu Pro Ser Tyr Val Ser Val Leu Val Ala Leu Gly Asn Leu
                  50                  55                  60

 Gly Leu Leu Val Val Thr Leu Trp Arg Arg Leu Ala Pro Gly Lys
                  65                  70                  75

 Asp Glu Gln Val Pro Ile Arg Val Val Gln Val Leu Gly Met Val
                  80                  85                  90

 Gly Thr Ala Leu Leu Ala Ser Leu Trp His His Val Ala Pro Val
                  95                 100                 105

 Ala Gly Gln Leu His Ser Val Ala Phe Leu Ala Leu Ala Phe Val
                 110                 115                 120

 Leu Ala Leu Ala Cys Cys Ala Ser Asn Val Thr Phe Leu Pro Phe
                 125                 130                 135

 Leu Ser His Leu Pro Pro Arg Phe Leu Arg Ser Phe Phe Leu Gly
                 140                 145                 150

 Gln Gly Leu Ser Ala Leu Leu Pro Cys Val Leu Ala Leu Val Gln
                 155                 160                 165

 Gly Val Gly Arg Leu Glu Cys Pro Pro Ala Pro Ile Asn Gly Thr
                 170                 175                 180

 Pro Gly Pro Pro Leu Asp Phe Leu Glu Arg Phe Pro Ala Ser Thr
                 185                 190                 195

 Phe Phe Trp Ala Leu Thr Ala Leu Leu Val Ala Ser Ala Ala Ala
                 200                 205                 210

 Phe Gln Gly Leu Leu Leu Leu Leu Pro Pro Pro Pro Ser Val Pro
                 215                 220                 225

 Thr Gly Glu Leu Gly Ser Gly Leu Gln Val Gly Ala Pro Gly Ala
                 230                 235                 240

 Glu Glu Glu Val Glu Glu Ser Ser Pro Leu Gln Glu Pro Pro Ser
                 245                 250                 255

 Gln Ala Ala Gly Thr Thr Pro Gly Pro Asp Pro Lys Ala Tyr Gln
                 260                 265                 270

 Leu Leu Ser Ala Arg Ser Ala Cys Leu Leu Gly Leu Leu Ala Ala
                 275                 280                 285

 Thr Asn Ala Leu Thr Asn Gly Val Leu Pro Ala Val Gln Ser Phe
                 290                 295                 300

 Ser Cys Leu Pro Tyr Gly Arg Leu Ala Tyr His Leu Ala Val Val
                 305                 310                 315

 Leu Gly Ser Ala Ala Asn Pro Leu Ala Cys Phe Leu Ala Met Gly
                 320                 325                 330

 Val Leu Cys Arg Ser Leu Ala Gly Leu Gly Gly Leu Ser Leu Leu
                 335                 340                 345

 Gly Val Phe Cys Gly Gly Tyr Leu Met Ala Leu Ala Val Leu Ser
                 350                 355                 360

 Pro Cys Pro Pro Leu Val Gly Thr Ser Ala Gly Val Val Leu Val
                 365                 370                 375

 Val Leu Ser Trp Val Leu Cys Leu Gly Val Phe Ser Tyr Val Lys
                 380                 385                 390

 Val Ala Ala Ser Ser Leu Leu His Gly Gly Gly Arg Pro Ala Leu
                 395                 400                 405

 Leu Ala Ala Gly Val Ala Ile Gln Val Gly Ser Leu Leu Gly Ala
                 410                 415                 420

 Val Ala Met Phe Pro Pro Thr Ser Ile Tyr His Val Phe His Ser
                 425                 430                 435

 Arg Lys Asp Cys Ala Asp Pro Cys Asp Ser
                 440                 445

<210> 3704
<211> 2952
<212> DNA
<213> Homo sapien

<400> 3704
 acaaactact ccctgagatc ctacaatccg cttcatttct aactgctaat 50

 ggggccttgt atatggcttt cttttgcatt ttaaggaaga tacttggaaa 100

 attctactca tggactcctg gctttggtgc cgctctgcca gcatcttatg 150

 tggccattct cattgaaaga aaaagcagga gagggctgct cacaatttat 200

 atggccaact tggtcctttt gttttgcatc acagctgcca tgtacatgtt 250

 ctttttcagg tgcaaggatg gcttgaaagg atttacattt tctgcactta 300

 ggttcattgt agggaaggaa gaaattccca cacattcttt ttcaccagag 350

 gcagcatatg caaaagtgga acaaaagaga gagcaacatg aggaaaaacc 400

 cagaagaatg aatatgattg gtctagtcag gaaatttgtg gattcaatat 450

 gcaaacatgg accaaggcat agatgttgca aacattatga agataattgc 500

 atctcttatt gcattaaagg tttcatcaga atgtttagcg tggggtactt 550

 gatccagtgc tgcctccgaa tcccttctgc atttaggcat ctgtttacac 600

 agccatctcg gctactttct ctcttctaca ataaagaaaa cttccagctt 650

 ggagcttttc ttggctcttt tgttagtata tacaagggta ctagttgctt 700

 cctgcgctgg atcagaaact tagatgatga actacatgct attatagctg 750

 gatttttggc aggtacatca atgatgtttt ataaaagcac aacaatttcc 800

 atgtatttag cgtccaaatt ggtagagaca atgtatttca aaggcattga 850

 agcagggaag gttccctatt ttcctcatgc agatactatc atctattcca 900

 tctctacagc aatttgcttc caggcagctg tcatggaagt tcagactttg 950

 agaccatctt actggaagtt ccttttaaga ctcaccaagg gcaaatttgc 1000

 tgtcatgaac cgaaaagtcc ttgatgtttt tggtactggt gcatctaaac 1050

 actttcagga tttcatcccc aggttggatc caagatacac aactgtaaca 1100

 ccagagttgc ccacagagtt ttcctgaaga tgactgtaac ttattaatgt 1150

 gactaaatgt ttcatcttga agagttaatt atgttgaaca caaaggaggg 1200

 ggcccaagct cgaacttcag tgttatttca gttagagata ctcttttcat 1250

 ttgttttgtt tttcttatga atcagaaatt cagaagcttt ttaggaagat 1300

 gttgcttaat aattaagctt cctccatagc cagaataaga ttctggatca 1350

 ctgtagtgac tgacattata tattattgat caaattatgt ccacaagcaa 1400

 tattatataa tctacgtaga agtgtaataa caaacaagag tacacttaaa 1450

 attactttaa aagatgtctt tagttcattc caatataatt cttgattaaa 1500

 attaggatta tttctacatt ttaggattta caaaggatca cgggtacatg 1550

 ggtttggtct atatattttt ttaaagtttt gaattggtat ctgtagtagt 1600

 ggaatgttat agatttgaag taactctcca cggacagtgc tgctttcgtg 1650

 tagagcaatt taattggaga agtggccatt cttacttcag ggatgcaaag 1700

 atgggtctca taccatttgg ataaatgtcg tggtatccat gctttttttc 1750

 aactaataac atcatctctc ttcatgacca gttaattggg ctatttggca 1800

 gcccagtgaa cctatgtact aatggcaagt taggggcaaa tggaaatgga 1850

 cacatccgtt aaagttgaaa tgtatgtttt aatctttcac agaagtatta 1900

 cacttgaata tttaaaaaca aaacttttaa acttcctata ggtttatgat 1950

 gtttgttttc atttatatgg acataatcct tcatagctca gtttatatgc 2000

 cattgttgta ttagaaggga tcaaaatcct atggaacaaa gtagtcttgg 2050

 caagttggca gtttgtgtcc tctcagctgt ttaacttatg taatggatgt 2100

 tttgcacctg aaaacactat aaaaatccag tggttgttta aaaagtccat 2150

 ttgtcactaa ttccattcag gttctccaac cttcttcttg aatatcattg 2200

 tcaccattta tactgttaga ataaagaggt gacaccataa agtcctgctg 2250

 ataatgagag tagttcagga cagctgtgat tgaaatatgg tcgctattta 2300

 cagtttttca gggaaaagtt atacttttct atgttaataa agagctgaag 2350

 tggtctacag ttaatgtgac atgtagggat gatgatattt ttaaaataca 2400

 ttttgttgct aaaaagttgt taggccagtg caaattatgc agtagaactt 2450

 gtgttgcaaa aggaattata acccatactt taaaaatgct taatccctca 2500

 tattcaattt catcaagcct tgtatacttc tgcttaaatg taattcaatc 2550

 cttggttgtt atggcaaaca gaaacccaac aaaaagacag actctggtac 2600

 tatggtaaca gagccacttt atcatttggt caaaatttga cattatgatt 2650

 agctttgtag aactgacctg tttatttggc aatgctgtta aaggatcatt 2700

 tcggtttcag acttcaaagt tgattaataa atttaatctt aactttttat 2750

 tcactggaat caaaacgatg gttggtactg tgtttactgt ttaaaatgaa 2800

 gtactaaagc cctgagaact gcacctcatt ttctttatcc agaaattgtg 2850

 cttatatatt ttcctgtcag gtttaaaaag atgttttaat tcataaatta 2900

 ttgttttcat tgacattaaa ggactgtgat attgaaaaaa aaaaaaaaaa 2950

 aa 2952

<210> 3705
<211> 354
<212> PRT
<213> Homo sapien

<400> 3705
 Met Ala Phe Phe Cys Ile Leu Arg Lys Ile Leu Gly Lys Phe Tyr
   1               5                  10                  15

 Ser Trp Thr Pro Gly Phe Gly Ala Ala Leu Pro Ala Ser Tyr Val
                  20                  25                  30

 Ala Ile Leu Ile Glu Arg Lys Ser Arg Arg Gly Leu Leu Thr Ile
                  35                  40                  45

 Tyr Met Ala Asn Leu Val Leu Leu Phe Cys Ile Thr Ala Ala Met
                  50                  55                  60

 Tyr Met Phe Phe Phe Arg Cys Lys Asp Gly Leu Lys Gly Phe Thr
                  65                  70                  75

 Phe Ser Ala Leu Arg Phe Ile Val Gly Lys Glu Glu Ile Pro Thr
                  80                  85                  90

 His Ser Phe Ser Pro Glu Ala Ala Tyr Ala Lys Val Glu Gln Lys
                  95                 100                 105

 Arg Glu Gln His Glu Glu Lys Pro Arg Arg Met Asn Met Ile Gly
                 110                 115                 120

 Leu Val Arg Lys Phe Val Asp Ser Ile Cys Lys His Gly Pro Arg
                 125                 130                 135

 His Arg Cys Cys Lys His Tyr Glu Asp Asn Cys Ile Ser Tyr Cys
                 140                 145                 150

 Ile Lys Gly Phe Ile Arg Met Phe Ser Val Gly Tyr Leu Ile Gln
                 155                 160                 165

 Cys Cys Leu Arg Ile Pro Ser Ala Phe Arg His Leu Phe Thr Gln
                 170                 175                 180

 Pro Ser Arg Leu Leu Ser Leu Phe Tyr Asn Lys Glu Asn Phe Gln
                 185                 190                 195

 Leu Gly Ala Phe Leu Gly Ser Phe Val Ser Ile Tyr Lys Gly Thr
                 200                 205                 210

 Ser Cys Phe Leu Arg Trp Ile Arg Asn Leu Asp Asp Glu Leu His
                 215                 220                 225

 Ala Ile Ile Ala Gly Phe Leu Ala Gly Thr Ser Met Met Phe Tyr
                 230                 235                 240

 Lys Ser Thr Thr Ile Ser Met Tyr Leu Ala Ser Lys Leu Val Glu
                 245                 250                 255

 Thr Met Tyr Phe Lys Gly Ile Glu Ala Gly Lys Val Pro Tyr Phe
                 260                 265                 270

 Pro His Ala Asp Thr Ile Ile Tyr Ser Ile Ser Thr Ala Ile Cys
                 275                 280                 285

 Phe Gln Ala Ala Val Met Glu Val Gln Thr Leu Arg Pro Ser Tyr
                 290                 295                 300

 Trp Lys Phe Leu Leu Arg Leu Thr Lys Gly Lys Phe Ala Val Met
                 305                 310                 315

 Asn Arg Lys Val Leu Asp Val Phe Gly Thr Gly Ala Ser Lys His
                 320                 325                 330

 Phe Gln Asp Phe Ile Pro Arg Leu Asp Pro Arg Tyr Thr Thr Val
                 335                 340                 345

 Thr Pro Glu Leu Pro Thr Glu Phe Ser
                 350

<210> 3706
<211> 2430
<212> DNA
<213> Homo sapien

<400> 3706
 cacacccgca ctcctcccgg gtttctgctc tccgcccgtg tggagtggtg 50

 ggggcctggg tgggaatggg cgtgtgccag cgcacgcgcg ctccctggaa 100

 ggagaagtct cagctagaac gagcggccct aggttttcgg aagggaggat 150

 cagggatgtt tgcgagcggc tggaaccaga cggtgccgat agaggaagcg 200

 ggctccatgg ctgccctcct gctgctgccc ctgctgctgt tgctaccgct 250

 gctgctgctg aagctacacc tctggccgca gttgcgctgg cttccggcgg 300

 acttggcctt tgcggtgcga gctctgtgct gcaaaagggc tcttcgagct 350

 cgcgccctgg ccgcggctgc cgccgacccg gaaggtcccg aggggggctg 400

 cagcctggcc tggcgcctcg cggaactggc ccagcagcgc gccgcgcaca 450

 cctttctcat tcacggctcg cggcgcttta gctactcaga ggcggagcgc 500

 gagagtaaca gggctgcacg cgccttccta cgtgcgctag gctgggactg 550

 gggacccgac ggcggcgaca gcggcgaggg gagcgctgga gaaggcgagc 600

 gggcagcgcc gggagccgga gatgcagcgg ccggaagcgg cgcggagttt 650

 gccggagggg acggtgccgc cagaggtgga ggagccgccg cccctctgtc 700

 acctggagca actgtggcgc tgctcctccc cgctggccca gagtttctgt 750

 ggctctggtt cgggctggcc aaggccggcc tgcgcactgc ctttgtgccc 800

 accgccctgc gccggggccc cctgctgcac tgcctccgca gctgcggcgc 850

 gcgcgcgctg gtgctggcgc cagagtttct ggagtccctg gagccggacc 900

 tgcccgccct gagagccatg gggctccacc tgtgggctgc aggcccagga 950

 acccaccctg ctggaattag cgatttgctg gctgaagtgt ccgctgaagt 1000

 ggatgggcca gtgccaggat acctctcttc cccccagagc ataacagaca 1050

 cgtgcctgta catcttcacc tctggcacca cgggcctccc caaggctgct 1100

 cggatcagtc atctgaagat cctgcaatgc cagggcttct atcagctgtg 1150

 tggtgtccac caggaagatg tgatctacct cgccctccca ctctaccaca 1200

 tgtccggttc cctgctgggc atcgtgggct gcatgggcat tggggccaca 1250

 gtggtgctga aatccaagtt ctcggctggt cagttctggg aagattgcca 1300

 gcagcacagg gtgacggtgt tccagtacat tggggagctg tgccgatacc 1350

 ttgtcaacca gcccccgagc aaggcagaac gtggccataa ggtccggctg 1400

 gcagtgggca gcgggctgcg cccagatacc tgggagcgtt ttgtgcggcg 1450

 cttcgggccc ctgcaggtgc tggagacata tggactgaca gagggcaacg 1500

 tggccaccat caactacaca ggacagcggg gcgctgtggg gcgtgcttcc 1550

 tggctttaca agcatatctt ccccttctcc ttgattcgct atgatgtcac 1600

 cacaggagag ccaattcggg acccccaggg gcactgtatg gccacatctc 1650

 caggtgagcc agggctgctg gtggccccgg taagccagca gtccccattc 1700

 ctgggctatg ctggcgggcc agagctggcc caggggaagt tgctaaagga 1750

 tgtcttccgg cctggggatg ttttcttcaa cactggggac ctgctggtct 1800

 gcgatgacca aggttttctc cgcttccatg atcgtactgg agacaccttc 1850

 aggtggaagg gggagaatgt ggccacaacc gaggtggcag aggtcttcga 1900

 ggccctagat tttcttcagg aggtgaacgt ctatggagtc actgtgccag 1950

 ggcatgaagg cagggctgga atggcagccc tagttctgcg tcccccccac 2000

 gctttggacc ttatgcagct ctacacccac gtgtctgaga acttgccacc 2050

 ttatgcccgg ccccgattcc tcaggctcca ggagtctttg gccaccacag 2100

 agaccttcaa acagcagaaa gttcggatgg caaatgaggg cttcgacccc 2150

 agcaccctgt ctgacccact gtacgttctg gaccaggctg taggtgccta 2200

 cctgcccctc acaactgccc ggtacagcgc cctcctggca ggaaaccttc 2250

 gaatctgaga acttccacac ctgaggcacc tgagagagga actctgtggg 2300

 gtgggggccg ttgcaggtgt actgggctgt cagggatctt ttctatacca 2350

 gaactgcggt cactattttg taataaatgt ggctggagct gatccagctg 2400

 tctctgacct acaaaaaaaa aaaaaaaaaa 2430

<210> 3707
<211> 730
<212> PRT
<213> Homo sapien

<400> 3707
 Met Gly Val Cys Gln Arg Thr Arg Ala Pro Trp Lys Glu Lys Ser
   1               5                  10                  15

 Gln Leu Glu Arg Ala Ala Leu Gly Phe Arg Lys Gly Gly Ser Gly
                  20                  25                  30

 Met Phe Ala Ser Gly Trp Asn Gln Thr Val Pro Ile Glu Glu Ala
                  35                  40                  45

 Gly Ser Met Ala Ala Leu Leu Leu Leu Pro Leu Leu Leu Leu Leu
                  50                  55                  60

 Pro Leu Leu Leu Leu Lys Leu His Leu Trp Pro Gln Leu Arg Trp
                  65                  70                  75

 Leu Pro Ala Asp Leu Ala Phe Ala Val Arg Ala Leu Cys Cys Lys
                  80                  85                  90

 Arg Ala Leu Arg Ala Arg Ala Leu Ala Ala Ala Ala Ala Asp Pro
                  95                 100                 105

 Glu Gly Pro Glu Gly Gly Cys Ser Leu Ala Trp Arg Leu Ala Glu
                 110                 115                 120

 Leu Ala Gln Gln Arg Ala Ala His Thr Phe Leu Ile His Gly Ser
                 125                 130                 135

 Arg Arg Phe Ser Tyr Ser Glu Ala Glu Arg Glu Ser Asn Arg Ala
                 140                 145                 150

 Ala Arg Ala Phe Leu Arg Ala Leu Gly Trp Asp Trp Gly Pro Asp
                 155                 160                 165

 Gly Gly Asp Ser Gly Glu Gly Ser Ala Gly Glu Gly Glu Arg Ala
                 170                 175                 180

 Ala Pro Gly Ala Gly Asp Ala Ala Ala Gly Ser Gly Ala Glu Phe
                 185                 190                 195

 Ala Gly Gly Asp Gly Ala Ala Arg Gly Gly Gly Ala Ala Ala Pro
                 200                 205                 210

 Leu Ser Pro Gly Ala Thr Val Ala Leu Leu Leu Pro Ala Gly Pro
                 215                 220                 225

 Glu Phe Leu Trp Leu Trp Phe Gly Leu Ala Lys Ala Gly Leu Arg
                 230                 235                 240

 Thr Ala Phe Val Pro Thr Ala Leu Arg Arg Gly Pro Leu Leu His
                 245                 250                 255

 Cys Leu Arg Ser Cys Gly Ala Arg Ala Leu Val Leu Ala Pro Glu
                 260                 265                 270

 Phe Leu Glu Ser Leu Glu Pro Asp Leu Pro Ala Leu Arg Ala Met
                 275                 280                 285

 Gly Leu His Leu Trp Ala Ala Gly Pro Gly Thr His Pro Ala Gly
                 290                 295                 300

 Ile Ser Asp Leu Leu Ala Glu Val Ser Ala Glu Val Asp Gly Pro
                 305                 310                 315

 Val Pro Gly Tyr Leu Ser Ser Pro Gln Ser Ile Thr Asp Thr Cys
                 320                 325                 330

 Leu Tyr Ile Phe Thr Ser Gly Thr Thr Gly Leu Pro Lys Ala Ala
                 335                 340                 345

 Arg Ile Ser His Leu Lys Ile Leu Gln Cys Gln Gly Phe Tyr Gln
                 350                 355                 360

 Leu Cys Gly Val His Gln Glu Asp Val Ile Tyr Leu Ala Leu Pro
                 365                 370                 375

 Leu Tyr His Met Ser Gly Ser Leu Leu Gly Ile Val Gly Cys Met
                 380                 385                 390

 Gly Ile Gly Ala Thr Val Val Leu Lys Ser Lys Phe Ser Ala Gly
                 395                 400                 405

 Gln Phe Trp Glu Asp Cys Gln Gln His Arg Val Thr Val Phe Gln
                 410                 415                 420

 Tyr Ile Gly Glu Leu Cys Arg Tyr Leu Val Asn Gln Pro Pro Ser
                 425                 430                 435

 Lys Ala Glu Arg Gly His Lys Val Arg Leu Ala Val Gly Ser Gly
                 440                 445                 450

 Leu Arg Pro Asp Thr Trp Glu Arg Phe Val Arg Arg Phe Gly Pro
                 455                 460                 465

 Leu Gln Val Leu Glu Thr Tyr Gly Leu Thr Glu Gly Asn Val Ala
                 470                 475                 480

 Thr Ile Asn Tyr Thr Gly Gln Arg Gly Ala Val Gly Arg Ala Ser
                 485                 490                 495

 Trp Leu Tyr Lys His Ile Phe Pro Phe Ser Leu Ile Arg Tyr Asp
                 500                 505                 510

 Val Thr Thr Gly Glu Pro Ile Arg Asp Pro Gln Gly His Cys Met
                 515                 520                 525

 Ala Thr Ser Pro Gly Glu Pro Gly Leu Leu Val Ala Pro Val Ser
                 530                 535                 540

 Gln Gln Ser Pro Phe Leu Gly Tyr Ala Gly Gly Pro Glu Leu Ala
                 545                 550                 555

 Gln Gly Lys Leu Leu Lys Asp Val Phe Arg Pro Gly Asp Val Phe
                 560                 565                 570

 Phe Asn Thr Gly Asp Leu Leu Val Cys Asp Asp Gln Gly Phe Leu
                 575                 580                 585

 Arg Phe His Asp Arg Thr Gly Asp Thr Phe Arg Trp Lys Gly Glu
                 590                 595                 600

 Asn Val Ala Thr Thr Glu Val Ala Glu Val Phe Glu Ala Leu Asp
                 605                 610                 615

 Phe Leu Gln Glu Val Asn Val Tyr Gly Val Thr Val Pro Gly His
                 620                 625                 630

 Glu Gly Arg Ala Gly Met Ala Ala Leu Val Leu Arg Pro Pro His
                 635                 640                 645

 Ala Leu Asp Leu Met Gln Leu Tyr Thr His Val Ser Glu Asn Leu
                 650                 655                 660

 Pro Pro Tyr Ala Arg Pro Arg Phe Leu Arg Leu Gln Glu Ser Leu
                 665                 670                 675

 Ala Thr Thr Glu Thr Phe Lys Gln Gln Lys Val Arg Met Ala Asn
                 680                 685                 690

 Glu Gly Phe Asp Pro Ser Thr Leu Ser Asp Pro Leu Tyr Val Leu
                 695                 700                 705

 Asp Gln Ala Val Gly Ala Tyr Leu Pro Leu Thr Thr Ala Arg Tyr
                 710                 715                 720

 Ser Ala Leu Leu Ala Gly Asn Leu Arg Ile
                 725                 730

<210> 3708
<211> 2270
<212> DNA
<213> Homo sapien

<400> 3708
 agtgtaagca gtgtgcaaac aaggtgttac agcacatgaa ggccgtgcag 50

 gcagatcagg agcgggagag gcagcggcgg ctggaagtag aacgtgaggc 100

 agagaagaag cgtgaggcta agcagcgagc taaggaagct caggagcggg 150

 aactgcggaa gcgggagaag gcggaagaga aggagcgccg gagaaaggag 200

 tatgatgccc tcaaagcagc caagcgggag caggagaaga aacctaagaa 250

 ggaagcaaat caggccccga aatctaagtc tggctcccgt ccccgcaagc 300

 caccaccccg gaagcacact cgttcctggg ctgtgctgaa gctgctgctg 350

 ctgctgctgc tatttggtgt ggcgggaggg ctggttgctt gtcgggtgac 400

 agagctgcag cagcagcccc tctgcaccag cgtgaacacc atctatgaca 450

 atgcggtcca gggtctacgc cgccatgaga tcctccagtg ggtccttcag 500

 accgactctc agcagtgagc ttgttcccag cacctgctgc ctcccagcct 550

 tggagtttgg attcctatgg aattgggttc tgctggacac aacctctttt 600

 tagcatcaga cctacctgcc atcatcaaat ggctgcagat tggtacatga 650

 gacctcctct ttgtaggact tcttcattcc ttagtcaggg ttccctgaag 700

 gaatgaggag aaatgggagg tggcgggggg gcgtgggggg cagttacctg 750

 catgcctaaa ggagtaggct tgggggtggg gagagagaaa acatagcctt 800

 ttctagttgt tatataaagc tgtgtaaagg caaggctcgt ttctactaaa 850

 tggtcagctg tcactacatt tatacttttg tatgccacaa accctttcat 900

 tcctccctgg gaatcagggt agatcaggag gaactggggg ggactagaac 950

 accacgctca gtaaatccag tctaaactgg gaggtagggg tattcctgtt 1000

 ttctttagga cctcagagat gtaagcattt tagcagccac acaaaatctc 1050

 tggctatgaa agggacttca tgaccatcca gtccaatata acacttgcag 1100

 acagagaaac tgaggtcttc catgacttgc ctagtctccc agctagtttg 1150

 aggcaaaact ggattcccac tctggtattc tttcttccct ttacatcatt 1200

 ttccctcctt tataatgtcc tgagagacca gaactcacac cagaatcgat 1250

 tattcctcag gtgaagcata gactctttca tggtagacag atttcacgac 1300

 tcagagatag aaatctcttg ctatcatcag gtcacgggca gctcctgtgg 1350

 agtcctgccc aacttatgtg gcttccataa aatggcaaca gtccaggctc 1400

 cttgcctaat tttagagcat taactcccta attgccagta agcaaggagg 1450

 tggatctctg caaacctaca ctgtctatga cagctctagt tgtacttggt 1500

 gtgactaaat acctcaaagg caacctgctt ctgcaggttt tgaagtgtca 1550

 gcttcataag acactgaggt ttagaattgt ttgattctag accataactg 1600

 aagggcataa atggaaacag gatatgaagg gaaacaagta gcatcatgga 1650

 gctgaaaagt ggtgcatcac ccaatggcta gcacaaacaa ggatcacact 1700

 gtccattctc ttgtctgcta aattaagcat tttcttgcct cctttgcttc 1750

 atcttttcac aacagctgga tagagggatc agaaatgact gtgtcatggt 1800

 gctcattcac tgcaaactcc cagttgcaag ctccttggct cccccggagg 1850

 gagcaagaat ctcatagttc agagacacag agggcctttt agccctaatg 1900

 accttttgga tgggactgca actcatgact atcctgatat tggaagaaag 1950

 gactttgtta atcttctccc ccatagctct gctgcgtagg tctacatctt 2000

 actcagaatc actacacatt cctttagtct tcctccaagc tccagagcca 2050

 ttggtacaaa tgctttattg aaactaaata cataatacac acaatgagat 2100

 gaagacaata tagaagtccg catagtcatc ataatcccgt tccttggccg 2150

 gttgaggcag ctcagtggct gagcccagtc aagccaaccc gcagcttcac 2200

 tcacgacttc aagatttgat gctaattctt ttggatttct acagttatta 2250

 aataagtgtc tgagtggaca 2270

<210> 3709
<211> 160
<212> PRT
<213> Homo sapien

<400> 3709
 Met Lys Ala Val Gln Ala Asp Gln Glu Arg Glu Arg Gln Arg Arg
   1               5                  10                  15

 Leu Glu Val Glu Arg Glu Ala Glu Lys Lys Arg Glu Ala Lys Gln
                  20                  25                  30

 Arg Ala Lys Glu Ala Gln Glu Arg Glu Leu Arg Lys Arg Glu Lys
                  35                  40                  45

 Ala Glu Glu Lys Glu Arg Arg Arg Lys Glu Tyr Asp Ala Leu Lys
                  50                  55                  60

 Ala Ala Lys Arg Glu Gln Glu Lys Lys Pro Lys Lys Glu Ala Asn
                  65                  70                  75

 Gln Ala Pro Lys Ser Lys Ser Gly Ser Arg Pro Arg Lys Pro Pro
                  80                  85                  90

 Pro Arg Lys His Thr Arg Ser Trp Ala Val Leu Lys Leu Leu Leu
                  95                 100                 105

 Leu Leu Leu Leu Phe Gly Val Ala Gly Gly Leu Val Ala Cys Arg
                 110                 115                 120

 Val Thr Glu Leu Gln Gln Gln Pro Leu Cys Thr Ser Val Asn Thr
                 125                 130                 135

 Ile Tyr Asp Asn Ala Val Gln Gly Leu Arg Arg His Glu Ile Leu
                 140                 145                 150

 Gln Trp Val Leu Gln Thr Asp Ser Gln Gln
                 155                 160

<210> 3710
<211> 390
<212> DNA
<213> Homo sapien

<400> 3710
 cttttttttt tttttttttt gagacagagt cttgctctgt tgctgaggct 50

 ggagtgcagt ggtgtgatct tggctcactg aaatctccgc ctccgggttc 100

 aagtgattct cctgcctcag cctcccgagt agctgggatt acaggcatgc 150

 accatcatac tcagctaatt tttgtatttt tagtagagac aggttcacat 200

 atgcagctgt ctgactcgac tctagtgatc accactgctc aaaatgctaa 250

 gattacagct agagcaccac gcgatctttt tttttttttt tttttttttt 300

 tttgagacag agtctgctct gttgtcgagg tcggagtgca gtggtgtgat 350

 ctggctcact gaatctcgct cggttcagtg atctcgctca 390

<210> 3711
<211> 100
<212> PRT
<213> Homo sapien

<400> 3711
 Phe Phe Phe Phe Phe Phe Glu Thr Glu Ser Cys Ser Val Ala Glu
   1               5                  10                  15

 Ala Gly Val Gln Trp Cys Asp Leu Gly Ser Leu Lys Ser Pro Pro
                  20                  25                  30

 Pro Gly Ser Ser Asp Ser Pro Ala Ser Ala Ser Arg Val Ala Gly
                  35                  40                  45

 Ile Thr Gly Met His His His Thr Gln Leu Ile Phe Val Phe Leu
                  50                  55                  60

 Val Glu Thr Gly Ser His Met Gln Leu Ser Asp Ser Thr Leu Val
                  65                  70                  75

 Ile Thr Thr Ala Gln Asn Ala Lys Ile Thr Ala Arg Ala Pro Arg
                  80                  85                  90

 Asp Leu Phe Phe Phe Phe Phe Phe Phe Phe
                  95                 100

<210> 3712
<211> 1676
<212> DNA
<213> Homo sapien

<400> 3712
 ccgacaacag gaattttctc cgagagcggg ccgggctcag ttcagctgct 50

 gtccagaccc ggatcggcaa cagtgccgcc tccagacgtt ctcctgccgc 100

 tcgcccgccc gtcccagcgc ccccagccct cccgcgaggg cgccccggga 150

 cggaaggatc caccagtctg tcggcgcccg ccgttctcgt ggtcgccgtc 200

 gccgtcgtcg tggtggtagt ctccgccgtc gcctgggcca tggccaatta 250

 catccacgtc cctcccggct ccccggaggt gcccaagctg aacgtcaccg 300

 ttcaggatca ggaggagcat cgctgccggg agggggccct gagcctcctg 350

 caacacctgc ggcctcactg ggacccccag gaggtgaccc tgcagctctt 400

 cacagatgga atcacaaata aacttattgg ctgttacgtg ggaaacacca 450

 tggaggatgt agtcctggtg agaatttatg gcaataagac tgagttatta 500

 gtcgatcgag atgaggaagt aaagagtttt cgagtgttgc aggctcatgg 550

 ggtgcaccac aactctactg taccttcaat aatggactat gctatgaatt 600

 tatacaagga gaagcactgg atccaaagca tgtctgcaac ccagccattt 650

 tcaggctaat agctcgtcag cttgctaaaa tccatgctat tcatgcacac 700

 aatggctgga tccccaaatc taatctttgg ctaaagatgg gaaagtattt 750

 ctctctcatt cccacaggat ttgcagatga agacattaat aaaaggttcc 800

 taagtgatat cccaagctct cagattctcc aggaagagat gacttggatg 850

 aaggagattc tttccaacct gggctcacct gttgtgcttt gccataatga 900

 cctattgtgt aagaatataa tctacaatga gaaacaaggt gatgtacagt 950

 tcattgatta tgaatattct ggatacaact acctggcata tgatattgga 1000

 aatcatttca atgaatttgc aggtgtgagt gatgtagact atagtctgta 1050

 tccagataga gaactacaga gtcagtggct gcgtgcttac cttgaagcct 1100

 acaaagaatt taagggcttt gggactgaag ttactgaaaa ggaggtagaa 1150

 atactcttca ttcaagtcaa tcagtttgca ttgggtgaaa acttgaattt 1200

 tatcattggc aacaaatatt gtcagttatt ttcactgaaa tggcttctca 1250

 tttcttttgg ggattgtggg ctttgattca agccaaatac tccactattg 1300

 agtttgattt ccttgggtat gcaattgttc gttttaacca gtactttaaa 1350

 atgaagcctg aggttactgc attaaaagtg cctgagtaaa gaagagattt 1400

 aattattctc cagtagctga gcaatgcttg tgaatctttt cttaagaaat 1450

 cccaaaaagc caatattagt taaaattctg ttgtttaatt tggttatctt 1500

 gctttataaa ttatgcctct aaacaatcaa atctattttt gaaatagact 1550

 gaatgatgtc aagaaatata cctactgcta tccgtatgtg gtggattaga 1600

 aatgtgttaa atctgcaaaa ggtataaaga tgtcagttta atttctttga 1650

 taatttaaaa aaaaaaaaaa aaaaaa 1676

<210> 3713
<211> 218
<212> PRT
<213> Homo sapien

<400> 3713
 Asp Asn Arg Asn Phe Leu Arg Glu Arg Ala Gly Leu Ser Ser Ala
   1               5                  10                  15

 Ala Val Gln Thr Arg Ile Gly Asn Ser Ala Ala Ser Arg Arg Ser
                  20                  25                  30

 Pro Ala Ala Arg Pro Pro Val Pro Ala Pro Pro Ala Leu Pro Arg
                  35                  40                  45

 Gly Arg Pro Gly Thr Glu Gly Ser Thr Ser Leu Ser Ala Pro Ala
                  50                  55                  60

 Val Leu Val Val Ala Val Ala Val Val Val Val Val Val Ser Ala
                  65                  70                  75

 Val Ala Trp Ala Met Ala Asn Tyr Ile His Val Pro Pro Gly Ser
                  80                  85                  90

 Pro Glu Val Pro Lys Leu Asn Val Thr Val Gln Asp Gln Glu Glu
                  95                 100                 105

 His Arg Cys Arg Glu Gly Ala Leu Ser Leu Leu Gln His Leu Arg
                 110                 115                 120

 Pro His Trp Asp Pro Gln Glu Val Thr Leu Gln Leu Phe Thr Asp
                 125                 130                 135

 Gly Ile Thr Asn Lys Leu Ile Gly Cys Tyr Val Gly Asn Thr Met
                 140                 145                 150

 Glu Asp Val Val Leu Val Arg Ile Tyr Gly Asn Lys Thr Glu Leu
                 155                 160                 165

 Leu Val Asp Arg Asp Glu Glu Val Lys Ser Phe Arg Val Leu Gln
                 170                 175                 180

 Ala His Gly Val His His Asn Ser Thr Val Pro Ser Ile Met Asp
                 185                 190                 195

 Tyr Ala Met Asn Leu Tyr Lys Glu Lys His Trp Ile Gln Ser Met
                 200                 205                 210

 Ser Ala Thr Gln Pro Phe Ser Gly
                 215

<210> 3714
<211> 1222
<212> DNA
<213> Homo sapien

<400> 3714
 ttgatgccac caatgatgag tttagtgtac ttaatctttt gcctctttga 50

 cttttttttt tcttttttaa gatgaatgat ttcggaatca agaatatgga 100

 ccaggtagcc cctgtggcta acagttacag agggacactc aaggtgagtg 150

 ggcaagtctt aatttttttt tttaattgga aaactcgatc tctaggagga 200

 aagaaaaaaa aggcctgggt cccagaaaac tggttgtagc cctagcttct 250

 taatttattg gccatgtgac tatagactat ttgcttactc gctctggtcc 300

 tcagttttct ggtctgcaga atgggtatct tgatgtgtgt tgttcttctc 350

 ctccacgata tgaaaccaaa ggcctttata gcttgttttc tgaggctcct 400

 tccaggtgaa aatcctataa ctcccaataa aacagctgga gaggctgtct 450

 ctactgcctt ttctgtctac ccaggagttt ccttggttga tgggaagctg 500

 tttaagaact gaaatgagag agaagaggca gacagaccca accgctacag 550

 ctcctatcag aaagggcagc gcccgtggaa ttgtaggtag cctgttactg 600

 gctcagagaa caagcaggcc tacttatgtt aaaccaaaaa ccagatgaaa 650

 aatgaaagcg ccctctctgc tgcataaaca ttttatgtag cttctatcat 700

 cattcctttt gggaacattc tttagtagca caaactggta atctcccact 750

 tgtcttctcc aaatatgaca gcaagatttg attgttttca gtattatgta 800

 gtaaacatgt ttcagaagca tgattttaaa attggcctcc tcaaagttta 850

 gcgtcttgca taatgatgat gtacgtctct ggcatattac attttccttt 900

 gtatatcatt attgaggtta tttgtctgat atgacccaaa gaggcaaaac 950

 tcagcacagt cctttctgca gtattctaaa ggtcatcaaa cttcagccta 1000

 gtgagtctgc ttgtttgatt tggccggaca ttttaagcat ggcagaagtg 1050

 gtacaagaaa tcatggtatt aagttgaaac cacacccctt agaaaaatcc 1100

 ttctattaat tcaaataatt tgacgatgct tatgcggttt ctgaaaagaa 1150

 gcagtcgttg ctgaaattga tgtgttgaaa taggaagcac agatttgtat 1200

 tgtcttttgg cttcctggct tt 1222

<210> 3715
<211> 24
<212> PRT
<213> Homo sapien

<400> 3715
 Leu Met Pro Pro Met Met Ser Leu Val Tyr Leu Ile Phe Cys Leu
   1               5                  10                  15

 Phe Asp Phe Phe Phe Ser Phe Leu Arg
                  20

<210> 3716
<211> 973
<212> DNA
<213> Homo sapien

<400> 3716
 gggattacag gcgtgagcca ctgtgcctga cccactcacc tgtcattgta 50

 gtacttaaga tgccttgttc atttattgtg cctgtgcaat aaatacacct 100

 tgatttgagt ttacaaagat tctcagcagt tggtggtcat cctcatctcc 150

 tgggcggggg cctcctggtg tggccagtat ctgaattagt ctcataactc 200

 atgttcactt tttaaaatcg gagcttccca gacctcagtt ttgttttgtt 250

 attttccatt atctgcagct gtctcctttc ccctctctca cctatactct 300

 actgatcagt gactgctggc tcctttgtta cccatccttc tctttctcca 350

 cattttttct cttctcatcc ctttcagttc tggactgttt ccttcttcct 400

 ccctgtcttt catttagtca ttcattgaat gtacttacta agcacatata 450

 gcataatcag gctgtgttgg gtaggcatcc cgagttctat gagataaaga 500

 aagaatggga tatgattacc aattttaaga agcatctaaa acaacctgtt 550

 atgttttagc aaattgcccc caaaggaccc attagggagg aaaacgttca 600

 tgtccttttt gcgtatcatc tcaagcagta cccatgatgg ctgggatccc 650

 agaacccacc tttgagaatg ctgccgtatt tgcgtgtggt tgacaaggtt 700

 gggccagaca ctcaggaaat agggttgtcg tcctacctcc cccactaact 750

 tcctgtaaga acttcagccc ctctcaggac ctttttcttt accaataaaa 800

 ttcagaaatt gggctcaatc agtaattccc aagttatttt ccaaagaaca 850

 tgaattttgt ggaactttaa tagatatcat gcaaaaaaaa atgtgggagg 900

 gattgttcca tggtcaaatg gtcttggaaa taactcgttt aaacaaaaat 950

 aaaactgttt ctttacccac aaa 973

<210> 3717
<211> 31
<212> PRT
<213> Homo sapien

<400> 3717
 Met Gln Lys Lys Met Trp Glu Gly Leu Phe His Gly Gln Met Val
   1               5                  10                  15

 Leu Glu Ile Thr Arg Leu Asn Lys Asn Lys Thr Val Ser Leu Pro
                  20                  25                  30

 Thr


<210> 3718
<211> 1540
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 867-1008
<223> Unknown base

<400> 3718
 aattatgtaa caaagtttac ataagggtct ctgacagaag aagcattttc 50

 ccacattgca tagtgacagc caaaatctta ataggtacaa taattaaagt 100

 tatgaaagaa ttgctattga atgaagaaaa tatttgtctt tagtgcttta 150

 ctttagatta ttttgagagg actatagtgt atagctaaga agcaatcatt 200

 caactcaggg taggtgggtt aggtttaaga aaatctgatg actccattga 250

 gaattgtatt aaagctcagc caagagagct gagctgtaac aatatttaat 300

 ttgccacatt gcagtttcat ccatctagaa gtgtaggaaa ttcaggtttt 350

 caggttcact caggatatga attgttaact tcctcttagc agagataata 400

 tattactatt taccagataa tcttaatact ctaacttata tttttacttc 450

 agaagttttt ctagaattta tctaggttac ttttagataa gtaaatcagg 500

 ccatttgttt gtatttatta ttggtatatt tctgtataat ttccttatgc 550

 ctgtgtagat cgtggagttc ttttgaagtc aatttcaagt caagattata 600

 tttatgtaca tgattttttt ctcatatttc tcactttccc accatatgat 650

 ctaggtttgc tacatcagaa ttggagagtg acatttaact tagtgtttcc 700

 ggaataaaga atctggagct tttactaccc cataagtaat ctattttagc 750

 ctttctaagt ctgcagcttc ctttcacttt gctttccaat ctagcatttc 800

 acctctagtt ttaccccagt tatgctttat agattaaacc tctgaaatgt 850

 gtttaatctg tatgaannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1000

 nnnnnnnnaa ataaataact aacagtaacc ttaaaatgaa attatggttc 1050

 ttaatgatag tggcttgtta catctcttat agccccacat aggttagatt 1100

 tttcaatata aaattagagg ataggcacat tctttctttt tagatgctta 1150

 agaaattacc tcacataaac attttaccat ttaaaaaatg atgtttacca 1200

 gtccatttca gttcttcaac tgaggtccat tataaaatat actacttttg 1250

 ctgtatacca agctacagtt gtagatattg attcaagtaa aggtgatact 1300

 tcctcttcca gttgattttt atactcttaa tttgtgtata catacatttt 1350

 cacacatgaa tatgtgtgtg taagagacag agtgcattca tttgcaccca 1400

 gggttggagg aaagaagaga aagaaatgag aatatgtata ttggagatac 1450

 ttggctattt gtacctcacc tgcccatgaa ggctaaaaat ggatggttaa 1500

 acacctgtct ctgtgctcat gatgaaaatg acctttgcac 1540

<210> 3719
<211> 46
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 867-1008
<223> Unknown amino acid

<400> 3719
 Leu Cys Asn Lys Val Tyr Ile Arg Val Ser Asp Arg Arg Ser Ile
   1               5                  10                  15

 Phe Pro His Cys Ile Val Thr Ala Lys Ile Leu Ile Gly Thr Ile
                  20                  25                  30

 Ile Lys Val Met Lys Glu Leu Leu Leu Asn Glu Glu Asn Ile Cys
                  35                  40                  45

 Leu


<210> 3720
<211> 3655
<212> DNA
<213> Homo sapien

<400> 3720
 agcgatccga ggcccggccc cggccccgcc ccgcgccgcg ccgcgccgct 50

 tgccgccggg ctagcactga cgtgtctctc ggcggagctg ctgtgcagtg 100

 gaacgcgctg ggccgcgggc agcgtcgcct cacgcggagc agagctgagc 150

 tgaagcggga cccggagccc gagcagccgc cgccatggca atcaaatttc 200

 tggaagtcat caagcccttc tgtgtcatcc tgccggaaat tcagaagcca 250

 gagaggaaga ttcagtttaa ggagaaagtg ctgtggaccg ctatcaccct 300

 ctttatcttc ttagtgtgct gccagattcc cctgtttggg atcatgtctt 350

 cagattcagc tgaccctttc tattggatga gagtgattct agcctctaac 400

 agaggcacat tgatggagct agggatctct cctattgtca cgtctggcct 450

 tataatgcaa ctcttggctg gcgccaagat aattgaagtt ggtgacaccc 500

 caaaagaccg agctctcttc aacggagccc aaaagttatt tggcatgatc 550

 attactatcg gccagtctat cgtgtatgtg atgaccggga tgtatgggga 600

 cccttctgaa atgggtgctg gaatttgcct gctaatcacc attcagctct 650

 ttgttgctgg cttaattgtc ctacttttgg atgaactcct gcaaaaagga 700

 tatggccttg gctctggtat ttctctcttc attgcaacta acatctgtga 750

 aaccatcgta tggaaggcat tcagccccac tactgtcaac actggccgag 800

 gaatggaatt tgaaggtgct atcatcgcac ttttccatct gctggccaca 850

 cgcacagaca aggtccgagc ccttcgggag gcgttctacc gccagaatct 900

 tcccaacctc atgaatctca tcgccaccat ctttgtcttt gcagtggtca 950

 tctatttcca gggcttccga gtggacctgc caatcaagtc ggcccgctac 1000

 cgtggccagt acaacaccta tcccatcaag ctcttctata cgtccaacat 1050

 ccccatcatc ctgcagtctg ccctggtgtc caacctttat gtcatctccc 1100

 aaatgctctc agctcgcttc agtggcaact tgctggtcag cctgctgggc 1150

 acctggtcgg acacgtcttc tgggggccca gcacgtgctt atccagttgg 1200

 tggcctttgc tattacctgt cccctccaga atcttttggc tccgtgttag 1250

 aagacccggt ccatgcagtt gtatacatag tgttcatgct gggctcctgt 1300

 gcattcttct ccaaaacgtg gattgaggtc tcaggttcct ctgccaaaga 1350

 tgttgcaaag cagctgaagg agcagcagat ggtgatgaga ggccaccgag 1400

 agacctccat ggtccatgaa ctcaaccggt acatccccac agccgcggcc 1450

 tttggtgggc tgtgcatcgg ggccctctcg gtcctggctg acttcctagg 1500

 cgccattggg tctggaaccg ggatcctgct cgcagtcaca atcatctacc 1550

 agtactttga gatcttcgtt aaggagcaaa gcgaggttgg cagcatgggg 1600

 gccctgctct tctgagcccg tctcccggac aggttgagga agctgctcca 1650

 gaagcgcctc ggaaggggag ctctcatcat ggcgcgtgct gctgcggcat 1700

 atggactttt aataatgttt ttgaatttcg tattctttca ttccactgtg 1750

 taaagtgcta gacattttcc aatttaaaat tttgcttttt atcctggcac 1800

 tggcaaaaag aactgtgaaa gtgaaatttt attcagccga ctgccagaga 1850

 agtgggaatg gtataggatt gtccccaagt gtccatgtaa cttttgtttt 1900

 aacctttgca ccttctcagt gctgtatgcg gctgcagccg tctcacctgt 1950

 ttccccacaa agggaatttc tcactctggt tggaagcaca aacactgaaa 2000

 tgtctacgtt tcattttggc agtagggtgt gaagctggga gcagatcatg 2050

 tatttcccgg agacgtggga ccttgctggc atgtctcctt cacaatcagg 2100

 cgtgggaata tctggcttag gactgtttct ctctaagaca ccattgtttt 2150

 cccttatttt aaaagtgatt tttttaagga cagaacttct tccaaaagag 2200

 agggatggct ttcccagaag acactcctgg ccatctgtgg atttgtctgt 2250

 gcacctattg gctcttctag ctgactcttc tggttgggct tagagtctgc 2300

 ctgtttctgc tagctccgtg tttagtccac ttgggtcatc agctctgcca 2350

 agctgagcct ggccaagcta ggtggacaga cccttgcagt gatgtccgtt 2400

 tgtccagatt ctgccagtca tcactggaca cgtctcctcg cagctgccct 2450

 agcaagggga gacattgtgg tagctatcag acatggacag aaactgactt 2500

 agtgctcaca agcccctaca ccttctgggc tgaagatcac ccagctgtgt 2550

 tcagaatttt cttactgtgc ttaggactgc acgcaagtga gcagacacca 2600

 ccgacttcct ttctgcgtca ccagtgtcgt cagcagagag aggacagcac 2650

 aggctcaagg ttggtagtga agtcaggttc ggggtgcatg ggctgtggtg 2700

 gtgttgatca gttgctccag tgtttgaaat aagaagactc atgtttatgt 2750

 ctggaataag ttctgtttgt gctgacaggt ggcctaggtc ctggagatga 2800

 gcaccctctc tctggccttt agggagtccc ctcttaggac aggcactgcc 2850

 cagcagcaag ggcagcagag ttgggtgcta agatcctgag gagctcgagg 2900

 tttcgagctg gctttagaca ttggtgggac caaggatgtt ttgcaggatg 2950

 ccctgatcct aagaaggggg cctgggggtg cgtgcagcct gtcggggaga 3000

 ccccactctg acagtgggca cacggcagcc tgcaaagcac agggccaccg 3050

 ccacagcccg gcagaggggc acactctgga gaccttgctg gcagtgctag 3100

 ccaggaaaca gagtgaccaa gggacaagaa gggacttgcc taaagccacc 3150

 cagcaactca gcagcagaac caagatgggc cccaggctcc tccatatggc 3200

 ccagggctta ccaccctatc acacgtggcc ttgtctagac ccagtcctga 3250

 gcaggggaga ggctcttgag acctgatgcc ctcctaccca catggttctc 3300

 ccactgccct gtctgctctg ctgctacaga ggggcagggc ctcccccagc 3350

 ccacgcttag gaatgcttgc ctctggcagg caggcagctg tacccaagct 3400

 ggtgggcagg gggctggaag gcaccaggcc tcaggaggag ccccatagtc 3450

 ccgcctgcag cctgtaacca tcggctgggc cctgcaaggc ccacactcac 3500

 gccctgtggg tgatggtcac ggtgggtggg tgggggctga ccccagcttc 3550

 caggggactg tcactgtgga cgccaaaatg gcataactga gataaggtga 3600

 ataagtgaca aataaagcca gttttttaca aggtaaaaaa aaaaaaaaaa 3650

 aaaaa 3655

<210> 3721
<211> 476
<212> PRT
<213> Homo sapien

<400> 3721
 Met Ala Ile Lys Phe Leu Glu Val Ile Lys Pro Phe Cys Val Ile
   1               5                  10                  15

 Leu Pro Glu Ile Gln Lys Pro Glu Arg Lys Ile Gln Phe Lys Glu
                  20                  25                  30

 Lys Val Leu Trp Thr Ala Ile Thr Leu Phe Ile Phe Leu Val Cys
                  35                  40                  45

 Cys Gln Ile Pro Leu Phe Gly Ile Met Ser Ser Asp Ser Ala Asp
                  50                  55                  60

 Pro Phe Tyr Trp Met Arg Val Ile Leu Ala Ser Asn Arg Gly Thr
                  65                  70                  75

 Leu Met Glu Leu Gly Ile Ser Pro Ile Val Thr Ser Gly Leu Ile
                  80                  85                  90

 Met Gln Leu Leu Ala Gly Ala Lys Ile Ile Glu Val Gly Asp Thr
                  95                 100                 105

 Pro Lys Asp Arg Ala Leu Phe Asn Gly Ala Gln Lys Leu Phe Gly
                 110                 115                 120

 Met Ile Ile Thr Ile Gly Gln Ser Ile Val Tyr Val Met Thr Gly
                 125                 130                 135

 Met Tyr Gly Asp Pro Ser Glu Met Gly Ala Gly Ile Cys Leu Leu
                 140                 145                 150

 Ile Thr Ile Gln Leu Phe Val Ala Gly Leu Ile Val Leu Leu Leu
                 155                 160                 165

 Asp Glu Leu Leu Gln Lys Gly Tyr Gly Leu Gly Ser Gly Ile Ser
                 170                 175                 180

 Leu Phe Ile Ala Thr Asn Ile Cys Glu Thr Ile Val Trp Lys Ala
                 185                 190                 195

 Phe Ser Pro Thr Thr Val Asn Thr Gly Arg Gly Met Glu Phe Glu
                 200                 205                 210

 Gly Ala Ile Ile Ala Leu Phe His Leu Leu Ala Thr Arg Thr Asp
                 215                 220                 225

 Lys Val Arg Ala Leu Arg Glu Ala Phe Tyr Arg Gln Asn Leu Pro
                 230                 235                 240

 Asn Leu Met Asn Leu Ile Ala Thr Ile Phe Val Phe Ala Val Val
                 245                 250                 255

 Ile Tyr Phe Gln Gly Phe Arg Val Asp Leu Pro Ile Lys Ser Ala
                 260                 265                 270

 Arg Tyr Arg Gly Gln Tyr Asn Thr Tyr Pro Ile Lys Leu Phe Tyr
                 275                 280                 285

 Thr Ser Asn Ile Pro Ile Ile Leu Gln Ser Ala Leu Val Ser Asn
                 290                 295                 300

 Leu Tyr Val Ile Ser Gln Met Leu Ser Ala Arg Phe Ser Gly Asn
                 305                 310                 315

 Leu Leu Val Ser Leu Leu Gly Thr Trp Ser Asp Thr Ser Ser Gly
                 320                 325                 330

 Gly Pro Ala Arg Ala Tyr Pro Val Gly Gly Leu Cys Tyr Tyr Leu
                 335                 340                 345

 Ser Pro Pro Glu Ser Phe Gly Ser Val Leu Glu Asp Pro Val His
                 350                 355                 360

 Ala Val Val Tyr Ile Val Phe Met Leu Gly Ser Cys Ala Phe Phe
                 365                 370                 375

 Ser Lys Thr Trp Ile Glu Val Ser Gly Ser Ser Ala Lys Asp Val
                 380                 385                 390

 Ala Lys Gln Leu Lys Glu Gln Gln Met Val Met Arg Gly His Arg
                 395                 400                 405

 Glu Thr Ser Met Val His Glu Leu Asn Arg Tyr Ile Pro Thr Ala
                 410                 415                 420

 Ala Ala Phe Gly Gly Leu Cys Ile Gly Ala Leu Ser Val Leu Ala
                 425                 430                 435

 Asp Phe Leu Gly Ala Ile Gly Ser Gly Thr Gly Ile Leu Leu Ala
                 440                 445                 450

 Val Thr Ile Ile Tyr Gln Tyr Phe Glu Ile Phe Val Lys Glu Gln
                 455                 460                 465

 Ser Glu Val Gly Ser Met Gly Ala Leu Leu Phe
                 470                 475

<210> 3722
<211> 1890
<212> DNA
<213> Homo sapien

<400> 3722
 ccgctccgct ccgctcggcc ccgcgccgcc cgtcaacatg atccgctgcg 50

 gcctggcctg cgagcgctgc cgctggatcc tgcccctgct cctactcagc 100

 gccatcgcct tcgacatcat cgcgctggcc ggccgcggct ggttgcagtc 150

 tagcgaccac ggccagacgt cctcgctgtg gtggaaatgc tcccaagagg 200

 gcggcggcag cgggtcctac gaggagggct gtcagagcct catggagtac 250

 gcgtggggta gagcagcggc tgccatgctc ttctgtggct tcatcatcct 300

 ggtgatctgt ttcatcctct ccttcttcgc cctctgtgga ccccagatgc 350

 ttgtcttcct gagagtgatt ggaggtctcc ttgccttggc tgctgtgttc 400

 cagatcatct ccctggtaat ttaccccgtg aagtacaccc agaccttcac 450

 ccttcatgcc aaccstgctg tcacttacat ctataactgg gcctacggct 500

 ttgggtgggc agccacgatt atcctgatyg gctgtgcctt cttcttctgc 550

 tgcctcccca actacgaaga tgaccttctg ggcaatgcca agcccaggta 600

 cttctacaca tctgcctaac ttgggaatga atgtgggaga aaatcgctgc 650

 tgctgagatg gactccagaa gaagaaactg tttctccagg cgactttgaa 700

 cccatttttt ggcagtgttc atattattaa actagtcaaa aatgctaaaa 750

 taatttggga gaaaatattt tttaagtagt gttatagttt catgtttatc 800

 ttttattatg ttttgtgaag ttgtgtcttt tcactaatta cctatactat 850

 gccaatattt ccttatatct atccataaca tttatactac atttgtaaga 900

 gaatatgcac gtgaaactta acactttata aggtaaaaat gaggtttcca 950

 agatttaata atctgatcaa gttcttgtta tttccaaata gaatggactc 1000

 ggtctgttaa gggctaagga gaagaggaag ataaggttaa aagttgttaa 1050

 tgaccaaaca ttctaaaaga aatgcaaaaa aaaagtttat tttcaagcct 1100

 tcgaactatt taaggaaagc aaaatcattt cctaaatgca tatcatttgt 1150

 gagaatttct cattaatatc ctgaatcatt catttcagct aaggcttcat 1200

 gttgactcga tatgtcatct aggaaagtac tatttcatgg tccaaacctg 1250

 ttgccatagt tggtaaggct ttcctttaag tgtgaaatat ttagatgaaa 1300

 ttttctcttt taaagttctt tatagggtta gggtgtggga aaatgctata 1350

 ttaataaatc tgtagtgttt tgtgtttata tgttcagaac cagagtagac 1400

 tggattgaaa gatggactgg gtctaattta tcatgactga tagatctggt 1450

 taagttgtgt agtaaagcat taggagggtc attcttgtca caaaagtgcc 1500

 actaaaacag cctcaggaga ataaatgact tgcttttcta aatctcaggt 1550

 ttatctgggc tctatcatat agacaggctt ctgatagttt gcaactgtaa 1600

 gcagaaacct acatatagtt aaaatcctgg tctttcttgg taaacagatt 1650

 ttaaatgtct gatataaaac atgccacagg agaattcggg gatttgagtt 1700

 tctctgaata gcatatatat gatgcatcgg ataggtcatt atgatttttt 1750

 accatttcga cttacataat gaaaaccaat tcattttaaa tatcagatta 1800

 ttattttgta agttgtggaa aaagctaatt gtagttttca ttatgaagtt 1850

 ttcccaataa accaggtatt ctaaaaaaaa aaaaaaaaaa 1890

<210> 3723
<211> 193
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 143, 164
<223> unknown amino acid

<400> 3723
 Met Ile Arg Cys Gly Leu Ala Cys Glu Arg Cys Arg Trp Ile Leu
   1               5                  10                  15

 Pro Leu Leu Leu Leu Ser Ala Ile Ala Phe Asp Ile Ile Ala Leu
                  20                  25                  30

 Ala Gly Arg Gly Trp Leu Gln Ser Ser Asp His Gly Gln Thr Ser
                  35                  40                  45

 Ser Leu Trp Trp Lys Cys Ser Gln Glu Gly Gly Gly Ser Gly Ser
                  50                  55                  60

 Tyr Glu Glu Gly Cys Gln Ser Leu Met Glu Tyr Ala Trp Gly Arg
                  65                  70                  75

 Ala Ala Ala Ala Met Leu Phe Cys Gly Phe Ile Ile Leu Val Ile
                  80                  85                  90

 Cys Phe Ile Leu Ser Phe Phe Ala Leu Cys Gly Pro Gln Met Leu
                  95                 100                 105

 Val Phe Leu Arg Val Ile Gly Gly Leu Leu Ala Leu Ala Ala Val
                 110                 115                 120

 Phe Gln Ile Ile Ser Leu Val Ile Tyr Pro Val Lys Tyr Thr Gln
                 125                 130                 135

 Thr Phe Thr Leu His Ala Asn Xaa Ala Val Thr Tyr Ile Tyr Asn
                 140                 145                 150

 Trp Ala Tyr Gly Phe Gly Trp Ala Ala Thr Ile Ile Leu Xaa Gly
                 155                 160                 165

 Cys Ala Phe Phe Phe Cys Cys Leu Pro Asn Tyr Glu Asp Asp Leu
                 170                 175                 180

 Leu Gly Asn Ala Lys Pro Arg Tyr Phe Tyr Thr Ser Ala
                 185                 190

<210> 3724
<211> 1689
<212> DNA
<213> Homo sapien

<400> 3724
 cgggagcgtg gggtatctcg aggtgccggg ttgcaggcgc tcaggggcgc 50

 tagggtttga ggcctgcttt ctgctcgcgc cagcagagca ctacctgagg 100

 cagcgaggcg cagcgagcct agcctccccg cgccctgggc agtgtggcca 150

 tggagaatca ggtgttgacg ccgcatgtct actgggctca gcgacaccgc 200

 gagctatatc tgcgcgtgga gctgagtgac gtacagaacc ctgccatcag 250

 catcactgaa aacgtgctgc atttcaaagc tcaaggacat ggtgccaaag 300

 gagacaatgt ctatgaattt cacctggagt tcttagacct tgtgaaacca 350

 gagcctgttt acaaactgac ccagaggcag gtaaacatta cagtacagaa 400

 gaaagtgagt cagtggtggg agagactcac aaagcaggaa aagcgaccac 450

 tgtttttggc tcctgacttt gatcgttggc tggatgaatc tgatgcggaa 500

 atggagctca gagctaagga agaagagcgc ctaaataaac tccgactgga 550

 aagcgaaggc tctcctgaaa ctcttacaaa cttaaggaaa ggatacctgt 600

 ttatgtataa tcttgtgcaa ttcttgggat tctcctggat ctttgtcaac 650

 ctgactgtgc gattctgtat cttgggaaaa gagtcctttt atgacacatt 700

 ccatactgtg gctgacatga tgtatttctg ccagatgctg gcagttgtgg 750

 aaactatcaa tgcagcaatt ggagtcacta cgtcaccggt gctgccttct 800

 ctgatccagc ttcttggaag aaattttatt ttgtttatca tctttggcac 850

 catggaagaa atgcagaaca aagctgtggt tttctttgtg ttttatttgt 900

 ggagtgcaat tgaaattttc aggtactctt tctacatgct gacgtgcatt 950

 gacatggatt ggaaggtgct cacatggctt cgttacactc tgtggattcc 1000

 cttatatcca ctgggatgtt tggtggaagc tgtctcagtg attcagtcca 1050

 ttccaatatt caatgagacc ggacgattca gtttcacatt gccatatcca 1100

 gtgaaaatca aagttagatt ttcctttttt cttcagattt atcttataat 1150

 gatattttta ggtttataca taaattttcg tcacctttat aaacagcgca 1200

 gacggcgcta tggaaaaaaa agaaaaagat ccactaaaaa gaaagattta 1250

 gatggcttct tgccagtttg agcctaatct gattcttaca gttttacctt 1300

 cttgaaccaa tgtaaaagtt tttttaatgt taaatgatta aattctcagt 1350

 gaggctatct tccttttccc cagtaacatt cctgaattta ctgttatctt 1400

 attgtagtac ttgcatgaca tggattcctg atatctgatg agaggttcat 1450

 tcttgtgtat tcagttaatg acaccaaaag gctcagccca ccccaaccct 1500

 atctcatgtt cagtctgtct aatacatgcc agagattttt ttttcaaaaa 1550

 gtgctttatc cctacaatgt actgacagtt cttacagttg aggatttggt 1600

 tcttttcagc taattgcttg gtggattaaa aaaagcaaga ctaatgtcaa 1650

 ctctaatgga aggctggtta aaagtggact caggcaagg 1689

<210> 3725
<211> 373
<212> PRT
<213> Homo sapien

<400> 3725
 Met Glu Asn Gln Val Leu Thr Pro His Val Tyr Trp Ala Gln Arg
   1               5                  10                  15

 His Arg Glu Leu Tyr Leu Arg Val Glu Leu Ser Asp Val Gln Asn
                  20                  25                  30

 Pro Ala Ile Ser Ile Thr Glu Asn Val Leu His Phe Lys Ala Gln
                  35                  40                  45

 Gly His Gly Ala Lys Gly Asp Asn Val Tyr Glu Phe His Leu Glu
                  50                  55                  60

 Phe Leu Asp Leu Val Lys Pro Glu Pro Val Tyr Lys Leu Thr Gln
                  65                  70                  75

 Arg Gln Val Asn Ile Thr Val Gln Lys Lys Val Ser Gln Trp Trp
                  80                  85                  90

 Glu Arg Leu Thr Lys Gln Glu Lys Arg Pro Leu Phe Leu Ala Pro
                  95                 100                 105

 Asp Phe Asp Arg Trp Leu Asp Glu Ser Asp Ala Glu Met Glu Leu
                 110                 115                 120

 Arg Ala Lys Glu Glu Glu Arg Leu Asn Lys Leu Arg Leu Glu Ser
                 125                 130                 135

 Glu Gly Ser Pro Glu Thr Leu Thr Asn Leu Arg Lys Gly Tyr Leu
                 140                 145                 150

 Phe Met Tyr Asn Leu Val Gln Phe Leu Gly Phe Ser Trp Ile Phe
                 155                 160                 165

 Val Asn Leu Thr Val Arg Phe Cys Ile Leu Gly Lys Glu Ser Phe
                 170                 175                 180

 Tyr Asp Thr Phe His Thr Val Ala Asp Met Met Tyr Phe Cys Gln
                 185                 190                 195

 Met Leu Ala Val Val Glu Thr Ile Asn Ala Ala Ile Gly Val Thr
                 200                 205                 210

 Thr Ser Pro Val Leu Pro Ser Leu Ile Gln Leu Leu Gly Arg Asn
                 215                 220                 225

 Phe Ile Leu Phe Ile Ile Phe Gly Thr Met Glu Glu Met Gln Asn
                 230                 235                 240

 Lys Ala Val Val Phe Phe Val Phe Tyr Leu Trp Ser Ala Ile Glu
                 245                 250                 255

 Ile Phe Arg Tyr Ser Phe Tyr Met Leu Thr Cys Ile Asp Met Asp
                 260                 265                 270

 Trp Lys Val Leu Thr Trp Leu Arg Tyr Thr Leu Trp Ile Pro Leu
                 275                 280                 285

 Tyr Pro Leu Gly Cys Leu Val Glu Ala Val Ser Val Ile Gln Ser
                 290                 295                 300

 Ile Pro Ile Phe Asn Glu Thr Gly Arg Phe Ser Phe Thr Leu Pro
                 305                 310                 315

 Tyr Pro Val Lys Ile Lys Val Arg Phe Ser Phe Phe Leu Gln Ile
                 320                 325                 330

 Tyr Leu Ile Met Ile Phe Leu Gly Leu Tyr Ile Asn Phe Arg His
                 335                 340                 345

 Leu Tyr Lys Gln Arg Arg Arg Arg Tyr Gly Lys Lys Arg Lys Arg
                 350                 355                 360

 Ser Thr Lys Lys Lys Asp Leu Asp Gly Phe Leu Pro Val
                 365                 370

<210> 3726
<211> 3221
<212> DNA
<213> Homo sapien

<400> 3726
 actgcgcagg cgcggcccgg gagcgtgggg tatctcgagg tgccgggttg 50

 caggcgctca ggagcgctag ggtttgaggc ctgctttctg ctcgcgccag 100

 cagagcacta cctgaggcag cgaggcgcag cgagcctagc ctccccgcgc 150

 cctgggcagt gtggccatgg agaatcaggt gttgacgccg catgtctact 200

 gggctcagcg acaccgcgag ctatatctgc gcgtggagct gagtgacgta 250

 cagaaccctg ccatcagcat cactgaaaac gtgctgcatt tcaaagctca 300

 aggacatggt gccaaaggag acaatgtcta tgaatttcac ctggagttct 350

 tagaccttgt gaaaccagag cctgtttaca aactgaccca gaggcaggta 400

 aacattacag tacagaagaa agtgagtcag tggtgggaga gactcacaaa 450

 gcaggaaaag cgaccactgt ttttggctcc tgactttgat cgttggctgg 500

 atgaatctga tgcggaaatg gagctcagag ctaaggaaga agagcgccta 550

 aataaactcc gactggaaag cgaaggctct cctgaaactc ttacaaactt 600

 aaggaaagga tacctgttta tgtataatct tgtgcaattc ttgggattct 650

 cctggatctt tgtcaacctg actgtgcgat tctgtatctt gggaaaagag 700

 tccttttatg acacattcca tactgtggct gacatgatgt atttctgcca 750

 gatgctggca gttgtggaaa ctatcaatgc agcgattgga gtcactacgt 800

 caccggtgct gccttctctg atccagcttc ttggaagaaa ttttattttg 850

 tttatcatct ttggcaccat ggaggaaatg cagaacaaag ctgtggttat 900

 ctttgtgttt tatttgtgga gtgcaattga aattttcagg tactctttct 950

 acatgctgac gtgcattgac atggattgga aggtgctcac atggcttcgt 1000

 tacactctgt ggattccctt atatccactg ggatgtttgg cggaagctgt 1050

 ctcagtgatt cagtccattc caatattcaa tgagaccgga cgattcagtt 1100

 tcacattgcc atatccagtg aaaatcaaag ttagattttc cttttttctt 1150

 cagatttatc ttataatgat atttttaggt ttatacataa attttcgtca 1200

 cctttataaa cagcgcagac ggcgctatgg acaaaaaaag aaaaagatcc 1250

 actaaaaaga aagatttaga tggcttcttg ccagtttgag cctaatctga 1300

 ttcttacagt tttaccttct tgaaccaatg taaaagtttt tttaatgtta 1350

 aatgattaaa ttctcagtga ggctatcttc cttttcccca gtaacattcc 1400

 tgaatttact gttatcttat tgtagtactt gcatgacatg gattcctgat 1450

 atctgatgag aggttcattc ttgtgtattc agttaatgac accaaaaggc 1500

 tcagcccacc ccaaccctat ctcatgttca gtctgtctaa tacatgccag 1550

 agattttttt ttcaaaaagt gctttatccc tacaatgtac tgacagttct 1600

 tacagttgag atttgttctt ttcagctatt gcttgtgaaa aaaagcaaga 1650

 ctatgtcact ctatagaagg ctgttaaagt gactcaggca ggaattaatt 1700

 attctgtacc taaggggtta cttgtttaat gggatggcat tgactttttg 1750

 aaaatcaagt ggactgagtc attgataaaa catttctaag agtggggcta 1800

 gagaacatac tttacatctg acatcctttg gcctaacaac atctattatt 1850

 atagtgctca gcagtgtggg cattgaagag gcgcagaatg ctttgaaaga 1900

 aactaatcag aatcttggaa catcatgatc atgccattct taagtaaatc 1950

 aactattttc aacactgaag aaaaatgaaa cattatttag aaaacaatga 2000

 gattacaagt tccaaactca gccaggaatg tggctcacac ctgtaatccc 2050

 agcactttgg gacacctagg tgggagcatc gcttgaagcc aggagttcaa 2100

 gaccagcttg ggcaacgtag tgagacccct atctctacaa aaaataaaaa 2150

 aattagctgg gtgtgatggc acacacctgt tgtcccagct actcaagaag 2200

 ctgagatggg aggatcctga gctcaggagg tcaaggctgc agtgagccga 2250

 gattgtgcca ctgcactgca gctggggtga cagtgcaaga ccctgtctca 2300

 aaccaaacca aaccacacac acacaaacac acatacacac acacacacac 2350

 gaggtccaaa tggtagcagg gatccaaagg gaacacagta tgtaggtcaa 2400

 actggcagta acagtgtaca gcctttgaca aactagaaat attagagtag 2450

 gccaaacaca cctccaaact gtaaggctgt gcacaaacat aaaaaatggc 2500

 agccttccat ctcctgcact ggctgagtcc atttacttgt gtacttgttc 2550

 tagtgagtgg tgggactgta catttttgaa tagacctcaa aaatacttca 2600

 ttctgctgct gttcagttgg ctttttaaac ctgtctgcag taggacactg 2650

 aaaacagcaa gaacttcggg gtgaacaccc gctgatcctt taacaaggat 2700

 ttctggcagg aaactcacaa aaaggagaac tgaaaattta gacatacagt 2750

 tggccattgt aaaaaacatc agtttcctct catacattcc aagtaaacca 2800

 agtaaaataa gtgttggagt aacacttgca taaaagaatt taaggagtga 2850

 tagctctttc tgttctgcca ttcccaacat tcctggggga aaggagactc 2900

 aatgagttaa tactatttca ctgagcccaa gatggaaact tggtttgacc 2950

 taaaacatct gattaatata ggctagctga tttcttaaaa attcgttgca 3000

 ttgaaggata ttttgcatgt ctgtaacacc tgtcaatact tgtttgtatt 3050

 gatttctgat attcttgcag ctgactacgt gtaattgggc agatcagctt 3100

 tgcagtagat tatgctgcat cctcgtggca aaattctgta ttcttagtga 3150

 ttgttacaaa cccctttatt gctgtctgag aaagtgaaag attgtgtatt 3200

 tctattaaaa catttacaat c 3221

<210> 3727
<211> 362
<212> PRT
<213> Homo sapien

<400> 3727
 Met Glu Asn Gln Val Leu Thr Pro His Val Tyr Trp Ala Gln Arg
   1               5                  10                  15

 His Arg Glu Leu Tyr Leu Arg Val Glu Leu Ser Asp Val Gln Asn
                  20                  25                  30

 Pro Ala Ile Ser Ile Thr Glu Asn Val Leu His Phe Lys Ala Gln
                  35                  40                  45

 Gly His Gly Ala Lys Gly Asp Asn Val Tyr Glu Phe His Leu Glu
                  50                  55                  60

 Phe Leu Asp Leu Val Lys Pro Glu Pro Val Tyr Lys Leu Thr Gln
                  65                  70                  75

 Arg Gln Val Asn Ile Thr Val Gln Lys Lys Val Ser Gln Trp Trp
                  80                  85                  90

 Glu Arg Leu Thr Lys Gln Glu Lys Arg Pro Leu Phe Leu Ala Pro
                  95                 100                 105

 Asp Phe Asp Arg Trp Leu Asp Glu Ser Asp Ala Glu Met Glu Leu
                 110                 115                 120

 Arg Ala Lys Glu Glu Glu Arg Leu Asn Lys Leu Arg Leu Glu Ser
                 125                 130                 135

 Glu Gly Ser Pro Glu Thr Leu Thr Asn Leu Arg Lys Gly Tyr Leu
                 140                 145                 150

 Phe Met Tyr Asn Leu Val Gln Phe Leu Gly Phe Ser Trp Ile Phe
                 155                 160                 165

 Val Asn Leu Thr Val Arg Phe Cys Ile Leu Gly Lys Glu Ser Phe
                 170                 175                 180

 Tyr Asp Thr Phe His Thr Val Ala Asp Met Met Tyr Phe Cys Gln
                 185                 190                 195

 Met Leu Ala Val Val Glu Thr Ile Asn Ala Ala Ile Gly Val Thr
                 200                 205                 210

 Thr Ser Pro Val Leu Pro Ser Leu Ile Gln Leu Leu Gly Arg Asn
                 215                 220                 225

 Phe Ile Leu Phe Ile Ile Phe Gly Thr Met Glu Glu Met Gln Asn
                 230                 235                 240

 Lys Ala Val Val Ile Phe Val Phe Tyr Leu Trp Ser Ala Ile Glu
                 245                 250                 255

 Ile Phe Arg Tyr Ser Phe Tyr Met Leu Thr Cys Ile Asp Met Asp
                 260                 265                 270

 Trp Lys Val Leu Thr Trp Leu Arg Tyr Thr Leu Trp Ile Pro Leu
                 275                 280                 285

 Tyr Pro Leu Gly Cys Leu Ala Glu Ala Val Ser Val Ile Gln Ser
                 290                 295                 300

 Ile Pro Ile Phe Asn Glu Thr Gly Arg Phe Ser Phe Thr Leu Pro
                 305                 310                 315

 Tyr Pro Val Lys Ile Lys Val Arg Phe Ser Phe Phe Leu Gln Ile
                 320                 325                 330

 Tyr Leu Ile Met Ile Phe Leu Gly Leu Tyr Ile Asn Phe Arg His
                 335                 340                 345

 Leu Tyr Lys Gln Arg Arg Arg Arg Tyr Gly Gln Lys Lys Lys Lys
                 350                 355                 360

 Ile His


<210> 3728
<211> 3828
<212> DNA
<213> Homo sapien

<400> 3728
 cagtgccagg ctggaggcgg cagcggttgg aggcttcgcc cggctttgca 50

 gcggggactt cggcggcggc gcctcaggca cctcggcccg gacacgatga 100

 ggcgagtggt acgacagagc aagtttcggc atgtatttgg gcaagcggtg 150

 aaaaatgacc agtgctatga tgacatccgg gtttctcgtg tgacctggga 200

 tagttccttt tgtgctgtca atcccagatt tgttgccata atcatagagg 250

 caagtggggg aggagcgttc cttgtcctcc ctctgcacaa gactggtcga 300

 attgacaaat cttaccctac agtatgtggc cacacaggac cagtgctgga 350

 catagactgg tgcccacata acgatcaggt cattgccagc ggttcagagg 400

 actgcacggt catggtatgg cagatcccag aaaatggact caccctttcc 450

 ctgactgaac ctgtggtgat tttggaaggc cactcaaaga gagtcggcat 500

 cgtggcttgg catccaacgg cccgcaatgt gcttcttagt gcaggctgtg 550

 ataatgccat tatcatctgg aatgtgggaa caggggaagc ccttataaac 600

 ttggacgata tgcattcaga catgatttac aatgtgagct ggaaccggaa 650

 tggcagtctg atctgcacag cttccaaaga caagaaagtg agagtcattg 700

 atcccaggaa acaagagatt gttgctgaga aggagaaagc acatgaagga 750

 gcaagaccca tgagagccat cttcctggcc gatggcaatg tcttcaccac 800

 tgggttcagc cgcatgagcg agcggcagct ggctctctgg aatccgaaaa 850

 atatgcagga accaattgct cttcatgaga tggacactag caatggggtg 900

 ttgctgcctt tctatgaccc tgacaccagc atcatttact tatgtggaaa 950

 gggtgacagc agtattcgct attttgagat cacggatgaa tccccgtacg 1000

 tccactacct caacacattc agcagcaagg agcctcagag agggatgggt 1050

 tacatgccca agaggggact tgatgttaac aaatgtgaga ttgccagatt 1100

 cttcaaactt catgagagaa agtgtgaacc tattattatg actgttccca 1150

 ggaagtctga ccttttccaa gatgacctgt atcctgacac agcggggcca 1200

 gaggccgcgc tggaggcaga agagtggttc gaaggcaaga atgcagaccc 1250

 aatcctcatc tccttgaagc acgggtacat tccaggcaaa aacagggatc 1300

 tcaaggtggt caagaagaac attctggata gcaagcccac tgcaaacaag 1350

 aagtgcgacc tgatcagcat ccccaagaaa accacagaca cggccagtgt 1400

 gcaaaatgaa gccaagttgg atgagatttt aaaagagatc aaatctataa 1450

 aagacacaat ctgcaatcaa gatgagcgta tttccaagtt agaacagcag 1500

 atggcaaaga tagcagcctg aaggtcccac ccccacccct acagaaaaaa 1550

 tgggagcaag aacttgtgct tgggagctgg ttattggtgt ggtcctaggg 1600

 agggcggaaa gggaggcact gccatttgga gacattccat ttcagatttg 1650

 tcaaccagcg ataggccaca ttccagtaag aactcaattt gtctcccaaa 1700

 tttgcagaaa caaaacgtga tttaaaagct gagcttttta tcagaaagct 1750

 tttttgatgt tttaagtgtt atgtgacttg ttgaactttt taaaaagtgc 1800

 tacttttaaa atcccagata ctctgaattt tagaaaacaa actaattctg 1850

 attgtgtcgt gcccaagtac cctttttttt ttaatgaata gggaccaatg 1900

 ccacattgct ttttatattt ctttcttttt taatgttgcc aaaaccaaaa 1950

 gtagctttgt tttcctttgt attttgctac tttgcagtat ttgtgtgtgt 2000

 ggtttttttt ccttaatttg aaagggacag cactgtgtat gtttataaac 2050

 taaatgaaga taagatatta ttttgtataa acattcatct gagaacaatc 2100

 aaagcagtag ccacatggtg ctggctcctt tgcagcacaa acctggtcat 2150

 tttgatgact gtacaacagg aagacttgaa aaatcacgtg gattcatatt 2200

 accaccgctc tcatttcatg gagtcttctg atcaaaaaag ctcacgtcgt 2250

 atttcttctt ttcctttctc ttttctagaa attgggtgtt tgtaccagaa 2300

 tggaattttg cttctcggtt atcctgtgct tcagatgatt ataatctaac 2350

 ccaaactagc atgtgtttct gcagtttgtt acacacctag gatcatattg 2400

 cattcatcac tttaaacatc atgtttcagg ttttggtcaa tacttgacaa 2450

 gggtgcccag gacaggaaga cgtgtactgc tgagtgttcc ttcttgccct 2500

 tttcagcagc ttgcccagct cttgagtaca gtggtgggga ctaaaaatgt 2550

 gggcatgtgg agaggggtat ttgccctggg tgatcctgtt tccctgtgct 2600

 gtccccatgc tgtgttggag gaggaagtgg ctctccttcc accaacaaag 2650

 ctcctgctct accctcttcc tcacatgtgc tgcgacctct ctcagggctc 2700

 ccccagccat tccttctttc cttcctgcct tttagctcta accacattaa 2750

 gctaagacaa ggccagaggg tgcgattgaa tgagtattga gactgaggag 2800

 aatgatagag agtgaagcag aaacaggagc acagacctct gctgtagctt 2850

 taatgcatac aaacatgtcc ctccgcacaa ctaacctgcc ctgcctctcc 2900

 atctctcacc aaggctgcgt caaagcacag aggctccccg gactcggagg 2950

 gggccagaga ctgagctctg gtcacctgtt cattcctcgg ttagctggaa 3000

 ctttgccccg tttccagttt cttatagtgc atgcttggga aacaagattt 3050

 aaggagcctc tgttttggaa gggctgtctg tgattgaacg tgaaatgtgt 3100

 agtgccattg ggaccacgaa gggaattctt gcacatgctc gtgctggtgt 3150

 gggcatggga ctggctggaa acgtctgtat gcagggagcc agggtgaggg 3200

 cagagtgtgg tgacagccga acttggagta atgtccgtgt agaaaaagga 3250

 ccatgttctt atccagccaa tactgggagt gctgtctcca caatttcagg 3300

 gcatctgaat gtttgatgtg gttttgtgtg tgtgtatgta tgtgtttaat 3350

 attgaagtgg atcatgagat gtaaagaaaa caataatggc aatgacttat 3400

 attcaaatct gtatttgttt ctttatcaat gtaatctgct gaggaccttt 3450

 tgtctaagat tcagtagtgt tttaaggttc tgatatcgaa ttaatgaagt 3500

 aaagttgttg atggtggtga aacaccgtag ggcatgtggt tcaaagagaa 3550

 gcaggagggc aagggaaagt taccctgatc ttagtttgta gcttatgact 3600

 tatttaatga atggatgccc agccaagctc agagtaggcg cccaaagcat 3650

 tgtggattat tttcctgttt tgtctttttt tttttttttt tttaagccat 3700

 gacatcccag aagaggacag tgaattactc ctaggtcggc tcttatagag 3750

 tggccatagt gttctgtcaa aacacttgct tccattttca gagataaaaa 3800

 tcattgatta caaaaaaaaa aaaaaaaa 3828

<210> 3729
<211> 474
<212> PRT
<213> Homo sapien

<400> 3729
 Met Arg Arg Val Val Arg Gln Ser Lys Phe Arg His Val Phe Gly
   1               5                  10                  15

 Gln Ala Val Lys Asn Asp Gln Cys Tyr Asp Asp Ile Arg Val Ser
                  20                  25                  30

 Arg Val Thr Trp Asp Ser Ser Phe Cys Ala Val Asn Pro Arg Phe
                  35                  40                  45

 Val Ala Ile Ile Ile Glu Ala Ser Gly Gly Gly Ala Phe Leu Val
                  50                  55                  60

 Leu Pro Leu His Lys Thr Gly Arg Ile Asp Lys Ser Tyr Pro Thr
                  65                  70                  75

 Val Cys Gly His Thr Gly Pro Val Leu Asp Ile Asp Trp Cys Pro
                  80                  85                  90

 His Asn Asp Gln Val Ile Ala Ser Gly Ser Glu Asp Cys Thr Val
                  95                 100                 105

 Met Val Trp Gln Ile Pro Glu Asn Gly Leu Thr Leu Ser Leu Thr
                 110                 115                 120

 Glu Pro Val Val Ile Leu Glu Gly His Ser Lys Arg Val Gly Ile
                 125                 130                 135

 Val Ala Trp His Pro Thr Ala Arg Asn Val Leu Leu Ser Ala Gly
                 140                 145                 150

 Cys Asp Asn Ala Ile Ile Ile Trp Asn Val Gly Thr Gly Glu Ala
                 155                 160                 165

 Leu Ile Asn Leu Asp Asp Met His Ser Asp Met Ile Tyr Asn Val
                 170                 175                 180

 Ser Trp Asn Arg Asn Gly Ser Leu Ile Cys Thr Ala Ser Lys Asp
                 185                 190                 195

 Lys Lys Val Arg Val Ile Asp Pro Arg Lys Gln Glu Ile Val Ala
                 200                 205                 210

 Glu Lys Glu Lys Ala His Glu Gly Ala Arg Pro Met Arg Ala Ile
                 215                 220                 225

 Phe Leu Ala Asp Gly Asn Val Phe Thr Thr Gly Phe Ser Arg Met
                 230                 235                 240

 Ser Glu Arg Gln Leu Ala Leu Trp Asn Pro Lys Asn Met Gln Glu
                 245                 250                 255

 Pro Ile Ala Leu His Glu Met Asp Thr Ser Asn Gly Val Leu Leu
                 260                 265                 270

 Pro Phe Tyr Asp Pro Asp Thr Ser Ile Ile Tyr Leu Cys Gly Lys
                 275                 280                 285

 Gly Asp Ser Ser Ile Arg Tyr Phe Glu Ile Thr Asp Glu Ser Pro
                 290                 295                 300

 Tyr Val His Tyr Leu Asn Thr Phe Ser Ser Lys Glu Pro Gln Arg
                 305                 310                 315

 Gly Met Gly Tyr Met Pro Lys Arg Gly Leu Asp Val Asn Lys Cys
                 320                 325                 330

 Glu Ile Ala Arg Phe Phe Lys Leu His Glu Arg Lys Cys Glu Pro
                 335                 340                 345

 Ile Ile Met Thr Val Pro Arg Lys Ser Asp Leu Phe Gln Asp Asp
                 350                 355                 360

 Leu Tyr Pro Asp Thr Ala Gly Pro Glu Ala Ala Leu Glu Ala Glu
                 365                 370                 375

 Glu Trp Phe Glu Gly Lys Asn Ala Asp Pro Ile Leu Ile Ser Leu
                 380                 385                 390

 Lys His Gly Tyr Ile Pro Gly Lys Asn Arg Asp Leu Lys Val Val
                 395                 400                 405

 Lys Lys Asn Ile Leu Asp Ser Lys Pro Thr Ala Asn Lys Lys Cys
                 410                 415                 420

 Asp Leu Ile Ser Ile Pro Lys Lys Thr Thr Asp Thr Ala Ser Val
                 425                 430                 435

 Gln Asn Glu Ala Lys Leu Asp Glu Ile Leu Lys Glu Ile Lys Ser
                 440                 445                 450

 Ile Lys Asp Thr Ile Cys Asn Gln Asp Glu Arg Ile Ser Lys Leu
                 455                 460                 465

 Glu Gln Gln Met Ala Lys Ile Ala Ala
                 470

<210> 3730
<211> 2944
<212> DNA
<213> Homo sapien

<400> 3730
 atatgatccg ctcggcttcc tgggtctggc tgctgccgcc cgccggtgtc 50

 cgcccgtgtc gcgccggggc accaaggagc cgttggaggg tccgggcgga 100

 ggcccgctcg tgtggaagtc gtcgacgccg ccgctcgtcc gtcctcccgt 150

 ccgttctcgc tcccggccgc catcatgctg gcgctcatct cccgcctgct 200

 ggactggttc cgttcgctct tctggaagga agagatggag ctgacgctcg 250

 tggggctgca gtactcgggc aagaccacct tcgtcaatgt catcgcgtca 300

 ggtcaattca gtgaagatat gatacccaca gtgggcttca acatgaggaa 350

 ggtaactaaa ggtaacgtca caataaagat ctgggacata ggaggacaac 400

 cccgatttcg aagcatgtgg gagcggtatt gcagaggagt caatgctatt 450

 gtttacatga tagatgctgc agatcgtgaa aagatagaag cttcccgaaa 500

 tgagctacat aatcttctag ataaaccaca gttacaagga attccagtgc 550

 tagtgcttgg aaacaagaga gatcttccta atgccttgga tgagaaacag 600

 ctaattgaaa aaatgaatct gtctgctatt caggatagag aaatttgctg 650

 ctattcaatt tcttgcaaag aaaaggataa tatagatatc acacttcagt 700

 ggcttattca gcattcaaaa tctagaagaa gctgaagcat ctcttgaagt 750

 cttccagtcc ttcttggcta taatcctaga attattgtcc gttcctctga 800

 agtaattccc agaatacggt ccttcctaaa ccccagaaat tgcctttttc 850

 agagtctatt tctcatgtgc actgctgaag atgaatatcc ctaatccttc 900

 ataaagaatc agctagagtt gtcatgataa agtcagcaca cacaaaaagg 950

 cttcttacac ataccaaaaa aaatgtctta aaccatgtgt agagctttaa 1000

 aaacagaaaa aaaaccccat atacttatga ccatcttaaa tcaagaaaat 1050

 tgcatatttc cattctggtc tttctgggcc agatttttat attggttttc 1100

 agtaaatgtc tatctataat atttcattat agagtccagt agcttaatac 1150

 tgacactgac ttgatacagc acgaagtttc tagtgccaca cacagtattt 1200

 agaaaacctt taggcgtgaa tgactcatgt gggatatatg taaacataat 1250

 gtttatttta tctcacaaat gcatgtgaaa tgtataatta catcttagga 1300

 atccaaaatg gtctgcagag agtgagcgga ggcaccagat caatgttggt 1350

 tctttgcact ggtgagattc tgcctgatga atattaaaga tatcctgctt 1400

 tctgagaact ctatcaccag atggcagttg ggatatggga ggaactaaag 1450

 catcctgttt tgtatctgtc cagatcatta tttctgtctc ttgttttttc 1500

 ttcctggttc aggatacttt tttaaggggt tgagaattga agattttcca 1550

 aaagcgttca tgaatttaga gcattccacc caatataata aaacctgtta 1600

 agaatgtcag tctttgttca aacatctgtt tgttctatct ccagtcatta 1650

 aatcagtgct gctgcatgac actcttaact cctgactttt tatatccagt 1700

 cataaagttg actttcagca caaaagatac ttataaacaa ataaaaaatt 1750

 tttatttttc tctcttactg atgtaagctt tggcactctt ttgactggtg 1800

 ccattagaca tcttgattat tgtgacaact ctagacctgc ctgctttatc 1850

 taatgtaatc atgctcaatg tctacaggtt gtttaataat cagtcacaca 1900

 gagaactgag gaactgatgc tgtttgtttg cttctatgat acagagatgt 1950

 ctaaaaactt caaatggaca tgttttgtag tttagcgact tccgtataca 2000

 taaagggaca tattaatact ggttcatttg taaattatta ttcatataga 2050

 ccactgtagt agataaaact ctatggtaca cctgcttatg tgttgcctca 2100

 cactgtgtgt gattttgttt cttttgttaa gcagcactta tgtagactgc 2150

 atttccaaat gtgttgagca ctcggagtgt agtcaacagt aagttctttt 2200

 aatgaatatc agttttaatt tatagactgc catggcctta aaaatattct 2250

 gtacaatata ctgcactgtg ttgcacagac actacttgct tttctccatt 2300

 catattttta tgagtagaat ctgggctttt aaatttctct tcttattctt 2350

 tgaagcatgt tgcatactac cctggtggga tggatggttc tgtaaatgaa 2400

 gggatattta aacttgctac tgttgttcaa caccattaat ggtcagtgtg 2450

 aaccattaca aagaatgtgg caacttgctt gtgcctaaaa ggaggaattg 2500

 gaactagaat gtgtgactct gtggggactg cataggtttg ttaattgacc 2550

 tatagctaaa ccttaatgtg tttgtgtgtc tatacattgc tttccgcatt 2600

 tcaagacatc cagacgctat taccaacatt ttcctgtgca ttaacctctg 2650

 catgtgaaaa cttttaacag ttactgaact atgtaaatat gtgaattttt 2700

 ttatttaggt ggatgcattt tttgtctgtt tactgctctt ctcagcttta 2750

 ttcaataaac ttgcatttta agggttgtat tggcaatttt aacttaaaat 2800

 gtgcatcatg atggaaggtg cagacttttt tggaagtttc cgagaggagg 2850

 gtctatagac catttgtcag aaatcagatc agccctcaaa gaatggggtc 2900

 tgtgggctag ttaaaataga aataaacttt taaaatatcc acag 2944

<210> 3731
<211> 186
<212> PRT
<213> Homo sapien

<400> 3731
 Met Leu Ala Leu Ile Ser Arg Leu Leu Asp Trp Phe Arg Ser Leu
   1               5                  10                  15

 Phe Trp Lys Glu Glu Met Glu Leu Thr Leu Val Gly Leu Gln Tyr
                  20                  25                  30

 Ser Gly Lys Thr Thr Phe Val Asn Val Ile Ala Ser Gly Gln Phe
                  35                  40                  45

 Ser Glu Asp Met Ile Pro Thr Val Gly Phe Asn Met Arg Lys Val
                  50                  55                  60

 Thr Lys Gly Asn Val Thr Ile Lys Ile Trp Asp Ile Gly Gly Gln
                  65                  70                  75

 Pro Arg Phe Arg Ser Met Trp Glu Arg Tyr Cys Arg Gly Val Asn
                  80                  85                  90

 Ala Ile Val Tyr Met Ile Asp Ala Ala Asp Arg Glu Lys Ile Glu
                  95                 100                 105

 Ala Ser Arg Asn Glu Leu His Asn Leu Leu Asp Lys Pro Gln Leu
                 110                 115                 120

 Gln Gly Ile Pro Val Leu Val Leu Gly Asn Lys Arg Asp Leu Pro
                 125                 130                 135

 Asn Ala Leu Asp Glu Lys Gln Leu Ile Glu Lys Met Asn Leu Ser
                 140                 145                 150

 Ala Ile Gln Asp Arg Glu Ile Cys Cys Tyr Ser Ile Ser Cys Lys
                 155                 160                 165

 Glu Lys Asp Asn Ile Asp Ile Thr Leu Gln Trp Leu Ile Gln His
                 170                 175                 180

 Ser Lys Ser Arg Arg Ser
                 185

<210> 3732
<211> 2787
<212> DNA
<213> Homo sapien

<400> 3732
 gcacagacga gatctcgatc gaaggcgaga tggcggacgt gctagatctt 50

 cacgaggctg ggggcgaaga tttcgccatg gatgaggatg gggacgagag 100

 cattcacaaa ctgaaagaaa aagcgaagaa acggaagggt cgcggctttg 150

 gctccgaaga ggggtcccga gcgcggatgc gtgaggatta tgacagcgtg 200

 gagcaggatg gcgatgaacc cggaccacaa cgctctgttg aaggctggat 250

 tctctttgta actggagtcc atgaggaagc caccgaagaa gacatacacg 300

 acaaattcgc agaatatggg gaaattaaaa acattcatct caacctcgac 350

 aggcgaacag gatatctgaa ggggtatact ctagttgaat atgaaacata 400

 caaggaagcc caggctgcta tggagggact caatggccag gatttgatgg 450

 gacagcccat cagcgttgac tggtgttttg ttcggggtcc accaaaaggc 500

 aagaggagag gtggccgaag acgcagcaga agtccagacc ggagacgtcg 550

 ctgacaggtc ctctgttgtc caggtgttct cttcaagatt ccatttgacc 600

 atgcagcctt ggacaaatag gactggggtg gaacttgctg tgtttatatt 650

 taatctctta ccgtatatgc gtagtatttg agttgcgaat aaatgttcca 700

 tttttgtttt ctacatttaa tgttactttc ctgtcctaaa attgaaagtt 750

 ctaaagcata gcaaggctgt atggatcatt gtgaagatac ttctagggac 800

 tgaactctat gtatttcttt tttttctttt ttttgagata gagtcttgct 850

 gtgttaccca gggtggattg cagctgatca tagctcactg cagcttcaaa 900

 ctcttgggct caagccatcc ttctgcctca ctgtccctag tagttgggat 950

 tacaggcaca tgccaccatg cccagctaaa tttttaatat ttttgtagag 1000

 atggggtctt gctgtgttac ctgggctagt tatgtgagtt tctatattag 1050

 acatagtctc aagtttcagg tagggtttaa agtagagaca ctggtcagta 1100

 tttctttttt ggggggaact aggagagcag gagtagaagt gagatgttaa 1150

 gatcttatgg cactaaagac ttactattct gttcctacat actctgttag 1200

 gatcagatag atgttataga aatgcctttt gtttctcctg cccttcttga 1250

 tgtcacagtt ttttgtactt ccagctgtct aaaggcatga atctcctctt 1300

 ggagcattct cccagaccct tctttagaag agtctatact aagttcttgg 1350

 tgccctcttc ggcagccaag ggtgaaggcc ccatagagga gaggatccaa 1400

 aggagcattg aggaggccca agaggaaaag gatgtggctc aggctgggag 1450

 ggacttcagt tagcatggtg ggggagaacc agtaccacat acccagtagg 1500

 taataaggtg tccagcagag gatgaaggtc agcaagataa gcagggccag 1550

 tctcagggcc cggagacgaa cacggggaca attgtcaaag gagcggggga 1600

 gggcaaattc accagcaggg gctaggaatt tagaaaatat actgtaattc 1650

 agacactcag cttctgatct gagtataggg tgaattgatg gaggggcata 1700

 gctagtgaga cagagctcgc ctcctacaag gaggagaatg ttgcaaaccg 1750

 ttttcccctt cccaacctgg gactatatga tttcttaccc ccagggatta 1800

 tgatagaaat atgaagccac caagtctaga cttgatggtg ttcaagaata 1850

 aataatactg attgcctccc tagtccttgt ccagctaact cagctgttta 1900

 taattgaagg gattcaacaa aattatctct agcatcaggt gctagacatg 1950

 gttagaatct caccatggtt tagtgactgg tagatagcta ttaggtaggt 2000

 agataaataa atgatgctag aggcaacagg tctagggtta aggattaagg 2050

 cctgggaatt ggagtctcac catggctccc cttccttgtc tggggcctgg 2100

 acacactgag gacaatgcgg ctatagcaga tggccatggc agtcagtggc 2150

 agcagaaaga ggcagcagaa ggtgaagagg ttataggtgg tctcttgcca 2200

 ttgagccttg aagctgcctt tggtgacaca ctgagtgaaa gggactgggc 2250

 cagctcagtg gaccgtgtgg aacaggaaca gctggagtgg agttgaggac 2300

 tattagaact ggttcccctc accacccaac ctacccacct atgtcatact 2350

 gtctcctccc aattcatcct taattccaag tgaagcagca cagtgctgag 2400

 aaacagttca tccatggtgc catgttaaag aagttggaaa tatatcttga 2450

 aaatcctatc ttccttttag gcttgaatat gatgctgaac agtaagtttg 2500

 ttaaatcttg gaacttaaaa caatcctgct ttctcaagta ctattctaac 2550

 attgcgcttt ataagggatg atatttctac cacctcactc atatttttag 2600

 ctgaaatgat tttcctggta tgtctgttat tttgtggaaa aagaaatatt 2650

 gtgtaaaatg ggtgctgcca aaattccagg ccattttgca gggactctga 2700

 agtgaccttt agtagtaata gtcttatgtg cagtaactat aatggtaaag 2750

 aatgttaaat aataaaattt aacattttcc aaatgct 2787

<210> 3733
<211> 174
<212> PRT
<213> Homo sapien

<400> 3733
 Met Ala Asp Val Leu Asp Leu His Glu Ala Gly Gly Glu Asp Phe
   1               5                  10                  15

 Ala Met Asp Glu Asp Gly Asp Glu Ser Ile His Lys Leu Lys Glu
                  20                  25                  30

 Lys Ala Lys Lys Arg Lys Gly Arg Gly Phe Gly Ser Glu Glu Gly
                  35                  40                  45

 Ser Arg Ala Arg Met Arg Glu Asp Tyr Asp Ser Val Glu Gln Asp
                  50                  55                  60

 Gly Asp Glu Pro Gly Pro Gln Arg Ser Val Glu Gly Trp Ile Leu
                  65                  70                  75

 Phe Val Thr Gly Val His Glu Glu Ala Thr Glu Glu Asp Ile His
                  80                  85                  90

 Asp Lys Phe Ala Glu Tyr Gly Glu Ile Lys Asn Ile His Leu Asn
                  95                 100                 105

 Leu Asp Arg Arg Thr Gly Tyr Leu Lys Gly Tyr Thr Leu Val Glu
                 110                 115                 120

 Tyr Glu Thr Tyr Lys Glu Ala Gln Ala Ala Met Glu Gly Leu Asn
                 125                 130                 135

 Gly Gln Asp Leu Met Gly Gln Pro Ile Ser Val Asp Trp Cys Phe
                 140                 145                 150

 Val Arg Gly Pro Pro Lys Gly Lys Arg Arg Gly Gly Arg Arg Arg
                 155                 160                 165

 Ser Arg Ser Pro Asp Arg Arg Arg Arg
                 170

<210> 3734
<211> 3655
<212> DNA
<213> Homo sapien

<400> 3734
 ggcacgaggc gctaggtaga gcgccgggac ctgtgacagg gctggtagca 50

 gcgcacagga aaggcggctt ttagccaggt atttcagtgt ctgtagacaa 100

 gatggaatca tctccattta atagacggca atggacctca ctatcattga 150

 gggtaacagc caaagaactt tctcttgtca acaagaacaa gtcatcggct 200

 attgtggaaa tattctccaa gtaccagaaa gcagctgaag aaacaaacat 250

 ggagaagaag agaagtaaca ccgaaaatct ctcccagcac tttagaaagg 300

 ggaccctgac tgtgttaaag aagaagtggg agaacccagg gctgggagca 350

 gagtctcaca cagactctct acggaacagc agcactgaga ttaggcacag 400

 agcagaccat cctcctgctg aagtgacaag ccacgctgct tctggagcca 450

 aagctgacca agaagaacaa atccacccca gatctagact caggtcacct 500

 cctgaagccc tcgttcaggg tcgatatccc cacatcaagg acggtgagga 550

 tcttaaagac cactcaacag aaagtaaaaa aatggaaaat tgtctaggag 600

 aatccaggca tgaagtagaa aaatcagaaa tcagtgaaaa cacagatgct 650

 tcgggcaaaa tagagaaata taatgttccg ctgaacaggc ttaagatgat 700

 gtttgagaaa ggtgaaccaa ctcaaactaa gattctccgg gcccaaagcc 750

 gaagtgcaag tggaaggaag atctctgaaa acagctattc tctagatgac 800

 ctggaaatag gcccaggtca gttgtcatct tctacatttg actcggagaa 850

 aaatgagagt agacgaaatc tggaacttcc acgcctctca gaaacctcta 900

 taaaggatcg aatggccaag taccaggcag ctgtgtccaa acaaagcagc 950

 tcaaccaact atacaaatga gctgaaagcc agtggtggcg aaatcaaaat 1000

 tcataaaatg gagcaaaagg agaatgtgcc cccaggtcct gaggtctgca 1050

 tcacccatca ggaaggggaa aagatttctg caaatgagaa tagcctggca 1100

 gtccgttcca cccctgccga agatgactcc cgtgactccc aggttaagag 1150

 tgaggttcaa cagcctgtcc atcccaagcc actaagtcca gattccagag 1200

 cctccagtct ttctgaaagt tctcctccca aagcaatgaa gaagtttcag 1250

 gcacctgcaa gagagacctg cgtggaatgt cagaagacag tctatccaat 1300

 ggagcgtctc ttggccaacc agcaggtgtt tcacatcagc tgcttccgtt 1350

 gctcctattg caacaacaaa ctcagtctag gaacatatgc atctttacat 1400

 ggaagaatct attgtaagcc tcacttcaat caactcttta aatctaaggg 1450

 caactatgat gaaggctttg ggcacagacc acacaaggat ctatgggcaa 1500

 gcaaaaatga aaacgaagag attttggaga gaccagccca gcttgcaaat 1550

 gcaagggaga cccctcacag cccaggggta gaagatgccc ctattgctaa 1600

 ggtgggtgtc ctggctgcaa gtatggaagc caaggcctcc tctcagcagg 1650

 agaaggaaga caagccagct gaaaccaaga agctgaggat cgcctggcca 1700

 ccccccactg aacttggaag ttcaggaagt gccttggagg aagggatcaa 1750

 aatgtcaaag cccaaatggc ctcctgaaga cgaaatcagc aagcccgaag 1800

 ttcctgagga tgtcgatcta gatctgaaga agctaagacg atcttcttca 1850

 ctgaaggaaa gaagccgccc attcactgta gcagcttcat ttcaaagcac 1900

 ctctgtcaag agcccaaaaa ctgtgtcccc acctatcagg aaaggctgga 1950

 gcatgtcaga gcagagtgaa gaatctgtgg gtggaagagt tgcagaaagg 2000

 aaacaagtgg aaaatgccaa ggcttctaag aagaatggga atgtgggaaa 2050

 aacaacctgg caaaacaaag aatctaaagg agagacaggg aagagaagta 2100

 aggaaggtca tagtttggag atggagaatg agaatcttgt agaaaatggt 2150

 gcagactccg atgaagatga taacagcttc ctcaaacaac aatctccaca 2200

 agaacccaag tctctgaatt ggtcgagttt tgtagacaac acctttgctg 2250

 aagaattcac tactcagaat cagaaatccc aggatgtgga actctgggag 2300

 ggagaagtgg tcaaagagct ctctgtggaa gaacagataa agagaaatcg 2350

 gtattatgat gaggatgagg atgaagagtg acaaattgca atgatgctgg 2400

 gccttaaatt catgttagtg ttagcgagcc actgcccttt gtcaaaatgt 2450

 gatgcacata agcaggtatc ccagcatgaa atgtaattta cttggaagta 2500

 actttggaaa agaattcctt cttaaaatca aaaacaaaac aaaaaaacac 2550

 aaaaaacaca ttctaaatac tagagataac tttacttaaa ttcttcattt 2600

 tagcagtgat gatatgcata agtgctgtaa ggcttgtaac tggggaaata 2650

 ttccacctga taatagccca gattctactg tattcccaaa aggcaatatt 2700

 aaggtagata gatgattagt agtatattgt tacacactat tttggaatta 2750

 gagaacatac agaaggaatt taggggctta aacattacga ctgaatgcac 2800

 tttagtataa agggcacagt ttgtatattt ttaaatgaat accaatttaa 2850

 ttttttagta tttacctgtt aagagattat ttagtcttta aattttttag 2900

 gttaattttc ttgctgtgat atatatgagg aatttactac tttatgtcct 2950

 gctctctaaa ctacatcctg aactcgacgt cctgaggtat aatacaacag 3000

 agcacttttt gaggcaattg aaaaaccaac ctacactctt cggtgcttag 3050

 agagatctgc tgtctcccaa ataagctttt gtatctgcca gtgaatttac 3100

 tgtactccaa atgattgctt tcttttctgg tgatatctgt gcttctcata 3150

 attactgaaa gctgcaatat tttagtaata ccttcgggat cactgtcccc 3200

 catcttccgt gttagagcaa agtgaagagt ttaaaggagg aagaagaaag 3250

 aactgtctta caccacttga gctcagacct ctaaaccctg tatttccctt 3300

 atgatgtccc ctttttgaga cactaatttt taaatactta ctagctctga 3350

 aatatattga tttttatcac agtattctca gggtgaaatt aaaccaacta 3400

 taggcctttt tcttgggatg attttctagt cttaaggttt ggggacatta 3450

 taaacttgag tacatttgtt gtacacagtt gatattccaa attgtatgga 3500

 tgggagggag aggtgtctta agctgtaggc ttttctttgt actgcattta 3550

 tagagattta gctttaatat tttttagaga tgtaaaacat tctgctttct 3600

 tagtcttacc tagtctgaaa catttttatt caataaagat tttaattaaa 3650

 atttg 3655

<210> 3735
<211> 759
<212> PRT
<213> Homo sapien

<400> 3735
 Met Glu Ser Ser Pro Phe Asn Arg Arg Gln Trp Thr Ser Leu Ser
   1               5                  10                  15

 Leu Arg Val Thr Ala Lys Glu Leu Ser Leu Val Asn Lys Asn Lys
                  20                  25                  30

 Ser Ser Ala Ile Val Glu Ile Phe Ser Lys Tyr Gln Lys Ala Ala
                  35                  40                  45

 Glu Glu Thr Asn Met Glu Lys Lys Arg Ser Asn Thr Glu Asn Leu
                  50                  55                  60

 Ser Gln His Phe Arg Lys Gly Thr Leu Thr Val Leu Lys Lys Lys
                  65                  70                  75

 Trp Glu Asn Pro Gly Leu Gly Ala Glu Ser His Thr Asp Ser Leu
                  80                  85                  90

 Arg Asn Ser Ser Thr Glu Ile Arg His Arg Ala Asp His Pro Pro
                  95                 100                 105

 Ala Glu Val Thr Ser His Ala Ala Ser Gly Ala Lys Ala Asp Gln
                 110                 115                 120

 Glu Glu Gln Ile His Pro Arg Ser Arg Leu Arg Ser Pro Pro Glu
                 125                 130                 135

 Ala Leu Val Gln Gly Arg Tyr Pro His Ile Lys Asp Gly Glu Asp
                 140                 145                 150

 Leu Lys Asp His Ser Thr Glu Ser Lys Lys Met Glu Asn Cys Leu
                 155                 160                 165

 Gly Glu Ser Arg His Glu Val Glu Lys Ser Glu Ile Ser Glu Asn
                 170                 175                 180

 Thr Asp Ala Ser Gly Lys Ile Glu Lys Tyr Asn Val Pro Leu Asn
                 185                 190                 195

 Arg Leu Lys Met Met Phe Glu Lys Gly Glu Pro Thr Gln Thr Lys
                 200                 205                 210

 Ile Leu Arg Ala Gln Ser Arg Ser Ala Ser Gly Arg Lys Ile Ser
                 215                 220                 225

 Glu Asn Ser Tyr Ser Leu Asp Asp Leu Glu Ile Gly Pro Gly Gln
                 230                 235                 240

 Leu Ser Ser Ser Thr Phe Asp Ser Glu Lys Asn Glu Ser Arg Arg
                 245                 250                 255

 Asn Leu Glu Leu Pro Arg Leu Ser Glu Thr Ser Ile Lys Asp Arg
                 260                 265                 270

 Met Ala Lys Tyr Gln Ala Ala Val Ser Lys Gln Ser Ser Ser Thr
                 275                 280                 285

 Asn Tyr Thr Asn Glu Leu Lys Ala Ser Gly Gly Glu Ile Lys Ile
                 290                 295                 300

 His Lys Met Glu Gln Lys Glu Asn Val Pro Pro Gly Pro Glu Val
                 305                 310                 315

 Cys Ile Thr His Gln Glu Gly Glu Lys Ile Ser Ala Asn Glu Asn
                 320                 325                 330

 Ser Leu Ala Val Arg Ser Thr Pro Ala Glu Asp Asp Ser Arg Asp
                 335                 340                 345

 Ser Gln Val Lys Ser Glu Val Gln Gln Pro Val His Pro Lys Pro
                 350                 355                 360

 Leu Ser Pro Asp Ser Arg Ala Ser Ser Leu Ser Glu Ser Ser Pro
                 365                 370                 375

 Pro Lys Ala Met Lys Lys Phe Gln Ala Pro Ala Arg Glu Thr Cys
                 380                 385                 390

 Val Glu Cys Gln Lys Thr Val Tyr Pro Met Glu Arg Leu Leu Ala
                 395                 400                 405

 Asn Gln Gln Val Phe His Ile Ser Cys Phe Arg Cys Ser Tyr Cys
                 410                 415                 420

 Asn Asn Lys Leu Ser Leu Gly Thr Tyr Ala Ser Leu His Gly Arg
                 425                 430                 435

 Ile Tyr Cys Lys Pro His Phe Asn Gln Leu Phe Lys Ser Lys Gly
                 440                 445                 450

 Asn Tyr Asp Glu Gly Phe Gly His Arg Pro His Lys Asp Leu Trp
                 455                 460                 465

 Ala Ser Lys Asn Glu Asn Glu Glu Ile Leu Glu Arg Pro Ala Gln
                 470                 475                 480

 Leu Ala Asn Ala Arg Glu Thr Pro His Ser Pro Gly Val Glu Asp
                 485                 490                 495

 Ala Pro Ile Ala Lys Val Gly Val Leu Ala Ala Ser Met Glu Ala
                 500                 505                 510

 Lys Ala Ser Ser Gln Gln Glu Lys Glu Asp Lys Pro Ala Glu Thr
                 515                 520                 525

 Lys Lys Leu Arg Ile Ala Trp Pro Pro Pro Thr Glu Leu Gly Ser
                 530                 535                 540

 Ser Gly Ser Ala Leu Glu Glu Gly Ile Lys Met Ser Lys Pro Lys
                 545                 550                 555

 Trp Pro Pro Glu Asp Glu Ile Ser Lys Pro Glu Val Pro Glu Asp
                 560                 565                 570

 Val Asp Leu Asp Leu Lys Lys Leu Arg Arg Ser Ser Ser Leu Lys
                 575                 580                 585

 Glu Arg Ser Arg Pro Phe Thr Val Ala Ala Ser Phe Gln Ser Thr
                 590                 595                 600

 Ser Val Lys Ser Pro Lys Thr Val Ser Pro Pro Ile Arg Lys Gly
                 605                 610                 615

 Trp Ser Met Ser Glu Gln Ser Glu Glu Ser Val Gly Gly Arg Val
                 620                 625                 630

 Ala Glu Arg Lys Gln Val Glu Asn Ala Lys Ala Ser Lys Lys Asn
                 635                 640                 645

 Gly Asn Val Gly Lys Thr Thr Trp Gln Asn Lys Glu Ser Lys Gly
                 650                 655                 660

 Glu Thr Gly Lys Arg Ser Lys Glu Gly His Ser Leu Glu Met Glu
                 665                 670                 675

 Asn Glu Asn Leu Val Glu Asn Gly Ala Asp Ser Asp Glu Asp Asp
                 680                 685                 690

 Asn Ser Phe Leu Lys Gln Gln Ser Pro Gln Glu Pro Lys Ser Leu
                 695                 700                 705

 Asn Trp Ser Ser Phe Val Asp Asn Thr Phe Ala Glu Glu Phe Thr
                 710                 715                 720

 Thr Gln Asn Gln Lys Ser Gln Asp Val Glu Leu Trp Glu Gly Glu
                 725                 730                 735

 Val Val Lys Glu Leu Ser Val Glu Glu Gln Ile Lys Arg Asn Arg
                 740                 745                 750

 Tyr Tyr Asp Glu Asp Glu Asp Glu Glu
                 755

<210> 3736
<211> 4113
<212> DNA
<213> Homo sapien

<400> 3736
 tgaggcgcgg gaggcccgcg ccccgcggct cgctgtgcgt gggagggcgc 50

 gagcgaacgc gggcgaggag cggccgagcc gctgaagagg agctgggcgc 100

 cggccgcccg gccgcgctcg gcccgcggat cgcctccgcc cggtcttcgc 150

 cggccccggc ccctggcgag atgccgtgtg gggaggattg gctcagccac 200

 ccgctgggaa tcgtgcaggg attcttcgcc caaaatggag ttaatcctga 250

 ctgggagaag aaagtaattg agtattttaa ggaaaagctg aaggaaaata 300

 atgctcctaa gtgggtacca tcactgaacg aagttcccct tcattatttg 350

 aaacctaata gttttgtgaa atttcgttgc atgattcagg atatgtttga 400

 ccctgagttt tacatgggag tttatgaaac ggttaaccaa aacacaaaag 450

 cacatgttct tcattttgga aaatatagag atgtagcaga gtgtgggcct 500

 caacaagaac ttgatttaaa ctctccacga aataccactt tggaaagaca 550

 gactttctat tgtgttccgg tgcctgggga atctacgtgg gtaaaagaag 600

 cctatgttaa tgcaaaccaa gctcgagtca gtccctcaac atcctacact 650

 cctagtcgcc acaagaggag ttatgaagat gatgacgata tggacctaca 700

 gcccaataag cagaaagacc aacatgcagg tgccagacaa gcagggagtg 750

 ttggtggtct tcaatggtgt ggagagccaa aacgtttaga aactgaagct 800

 tctactgggc aacagctgaa ctctctgaac ttgtcttctc cttttgattt 850

 gaattttcca ttgccaggag agaagggccc tgcatgcctt gtgaaggttt 900

 atgaagattg ggattgtttc aaagtaaatg acattcttga gctatatggc 950

 atactgtctg tggatcctgt gctgagtata ctgaataatg atgaaaggga 1000

 tgcctctgca ctgctggatc cgatggagtg cacagacaca gcagaggagc 1050

 agagagtaca cagtcctcct gcttcattag tgccgagaat tcatgtgatc 1100

 ttagcccaga agttgcaaca catcaaccca ttattgcctg cctgccttaa 1150

 caaagaggag agcaaaacct gtaagtttgt ttcaagtttc atgtccgaat 1200

 tgtctccagt cagagcagaa cttcttgggt tccttactca tgcccttctg 1250

 ggggatagtt tggctgctga ataccttata ttacatctca tctccacagt 1300

 atatacaaga agagatgtcc ttccactagg aaaatttaca gttaacttga 1350

 gtggttgccc acggaatagt accttcacag aacacttgta tcgaattatt 1400

 caacatcttg ttccagcatc ttttcgtctg cagatgacta tagagaacat 1450

 gaaccatttg aaattcattc cccacaaaga ctacacagcc aatcgcttgg 1500

 tcagtgggct cctccagctg cccagcaata cttcccttgt aatcgatgag 1550

 actctcctgg aacaggggca gctggatacc ccaggtgttc ataatgtgac 1600

 agccctgagc aacctcataa cgtggcagaa ggtggattat gacttcagct 1650

 accatcagat ggaattcccc tgcaatatta acgttttcat tacttcggag 1700

 gggaggtcac tcctcccggc agactgccag attcacttac agccccagct 1750

 aattccacca aacatggagg agtacatgaa cagccttctc tcagcggtgc 1800

 tgccttccgt gctgaacaaa ttccgcattt atctaactct tttgagattc 1850

 ttggaatata gcatatctga tgaaataacc aaggcagttg aagatgactt 1900

 tgtggaaatg cggaagaacg accctcagag catcactgct gatgatcttc 1950

 accagctgct cgtggtggct cggtgtctgt ctctcagtgc tggtcagaca 2000

 acgctgtcaa gagaacgatg gctgagagca aagcagctag agtctttaag 2050

 aagaacgagg cttcagcagc aaaaatgtgt gaatggaaat gaactttaaa 2100

 gatgtaatac ctatgaagag taatgggcaa actgtagcca cataattgta 2150

 aaattcagat attcatttat accacattgt tttataggta atttctatca 2200

 caaaccagtg acatttcctg aaatcaagcc tggtaacacc tgatgtttat 2250

 atgatattca gtaaggactt ttaccttact gatttcatgg agcttttgaa 2300

 gtttgtttta taataattat ataaattagt aatgatgtaa aaaaagtatt 2350

 tgatattaaa agtttaatat tgataatgtt gctgattgta ccatttcctt 2400

 agcttcagct gagtcatagg ccagactgtt gaaatgctga aatgaagaag 2450

 gttgttgcag tttcaaagtc agaggaatcg tgcttcggat ttcttatgtt 2500

 ttctagttct ctgtttttcc agttcacagt gggttggggt gcattcagta 2550

 gtccatcttt ggggaacgga ggcgtacttg ccattgattc acatgactac 2600

 atgaaattct gtactgtcat ttcccagatg tttggccaca gaaacttttt 2650

 cccacttaac atttgttaac agcctgcaaa actaaacttg tacatggcag 2700

 tggttcccag acttttgtat tttatggacc ggtagtaata tttccaaaaa 2750

 tctggggtac tataaggttg ccaatttacc ttgccaagta atccgaataa 2800

 atcactgtat tatcaccatt tttttcataa aaggaaagga caatctatct 2850

 ctgaataaga ggagtccttt aaacggaatg aatgtggctt ttgggggcaa 2900

 aagaaaccaa gacactacat tgtctttatt ttctcctatc ccagtgcatt 2950

 tgagaaccat gcataaggga atgctgtgct acaaagctgt gcccaaatat 3000

 gaaaacaaaa taggaaactt aaaaagcaat acccccttta gaaagttttt 3050

 attttcttaa atgtcattga gttgctttga ttctattgga tttttggcat 3100

 tttttatggg atcatcagtt ggttccaagt atgttagatc agctaacatc 3150

 tgctactcca gtaacagcct cgtacaactg caggtaggtt ttctccagac 3200

 caattagttt taatagagca aactaacaac agactgtagt agcatggtta 3250

 tggcaaccag aatcttcaga aaggttagga cattactttt taagctgtca 3300

 gtggtatcaa ataacttacc tagttggagg cagataaagg atcccttacg 3350

 ttttttccta taaggcctaa attgaaattg ttaaccaagg aaacagggtc 3400

 agccttgaaa aatcaaggaa ttcattgtac ctaataactg aagtaaaaat 3450

 aactagttgt tcaacttttc ctaaactcaa atctattttt ataaacaaat 3500

 gtaaataatg tttatattag agttgaactg gttttcattt ttataactgg 3550

 tagactagac cttccttaaa cttttagaaa taaaatgaag gcttcactgg 3600

 atttgtgagg ataaaataca ttttctttaa ttgtcctaga gcaaagtaca 3650

 ttagtcacca tgtgtttttt gtgccaatgt aacttgtaat ttaccaaaga 3700

 aaaatacata cattgcttgg tcttgcagaa aagttccctt gaaagaacct 3750

 ttccaataaa taaaacgtcc caaattagca gtaccttggg ctgtttttca 3800

 tgagtaagaa gattcaccat cccatgtgat ctgtgtggaa aaagaccatg 3850

 tcctcttggt ggaagacatg agagagctga actgaagtgg aggaggtggt 3900

 gcaagaggga ccttcctgct caaggcccgc ccaggcagcg gaatagagtg 3950

 cagtgcttgg ctgcagaaac cctttgtccc tcacctatat atacacggac 4000

 agtcaagttt gttgctctaa cgtaaggcac agcgttaatc ctgtatggcc 4050

 aggaaactga gtagactcct gtgtaaccct gtttggaact ttgccttctt 4100

 aaaatgattt ttc 4113

<210> 3737
<211> 642
<212> PRT
<213> Homo sapien

<400> 3737
 Met Pro Cys Gly Glu Asp Trp Leu Ser His Pro Leu Gly Ile Val
   1               5                  10                  15

 Gln Gly Phe Phe Ala Gln Asn Gly Val Asn Pro Asp Trp Glu Lys
                  20                  25                  30

 Lys Val Ile Glu Tyr Phe Lys Glu Lys Leu Lys Glu Asn Asn Ala
                  35                  40                  45

 Pro Lys Trp Val Pro Ser Leu Asn Glu Val Pro Leu His Tyr Leu
                  50                  55                  60

 Lys Pro Asn Ser Phe Val Lys Phe Arg Cys Met Ile Gln Asp Met
                  65                  70                  75

 Phe Asp Pro Glu Phe Tyr Met Gly Val Tyr Glu Thr Val Asn Gln
                  80                  85                  90

 Asn Thr Lys Ala His Val Leu His Phe Gly Lys Tyr Arg Asp Val
                  95                 100                 105

 Ala Glu Cys Gly Pro Gln Gln Glu Leu Asp Leu Asn Ser Pro Arg
                 110                 115                 120

 Asn Thr Thr Leu Glu Arg Gln Thr Phe Tyr Cys Val Pro Val Pro
                 125                 130                 135

 Gly Glu Ser Thr Trp Val Lys Glu Ala Tyr Val Asn Ala Asn Gln
                 140                 145                 150

 Ala Arg Val Ser Pro Ser Thr Ser Tyr Thr Pro Ser Arg His Lys
                 155                 160                 165

 Arg Ser Tyr Glu Asp Asp Asp Asp Met Asp Leu Gln Pro Asn Lys
                 170                 175                 180

 Gln Lys Asp Gln His Ala Gly Ala Arg Gln Ala Gly Ser Val Gly
                 185                 190                 195

 Gly Leu Gln Trp Cys Gly Glu Pro Lys Arg Leu Glu Thr Glu Ala
                 200                 205                 210

 Ser Thr Gly Gln Gln Leu Asn Ser Leu Asn Leu Ser Ser Pro Phe
                 215                 220                 225

 Asp Leu Asn Phe Pro Leu Pro Gly Glu Lys Gly Pro Ala Cys Leu
                 230                 235                 240

 Val Lys Val Tyr Glu Asp Trp Asp Cys Phe Lys Val Asn Asp Ile
                 245                 250                 255

 Leu Glu Leu Tyr Gly Ile Leu Ser Val Asp Pro Val Leu Ser Ile
                 260                 265                 270

 Leu Asn Asn Asp Glu Arg Asp Ala Ser Ala Leu Leu Asp Pro Met
                 275                 280                 285

 Glu Cys Thr Asp Thr Ala Glu Glu Gln Arg Val His Ser Pro Pro
                 290                 295                 300

 Ala Ser Leu Val Pro Arg Ile His Val Ile Leu Ala Gln Lys Leu
                 305                 310                 315

 Gln His Ile Asn Pro Leu Leu Pro Ala Cys Leu Asn Lys Glu Glu
                 320                 325                 330

 Ser Lys Thr Cys Lys Phe Val Ser Ser Phe Met Ser Glu Leu Ser
                 335                 340                 345

 Pro Val Arg Ala Glu Leu Leu Gly Phe Leu Thr His Ala Leu Leu
                 350                 355                 360

 Gly Asp Ser Leu Ala Ala Glu Tyr Leu Ile Leu His Leu Ile Ser
                 365                 370                 375

 Thr Val Tyr Thr Arg Arg Asp Val Leu Pro Leu Gly Lys Phe Thr
                 380                 385                 390

 Val Asn Leu Ser Gly Cys Pro Arg Asn Ser Thr Phe Thr Glu His
                 395                 400                 405

 Leu Tyr Arg Ile Ile Gln His Leu Val Pro Ala Ser Phe Arg Leu
                 410                 415                 420

 Gln Met Thr Ile Glu Asn Met Asn His Leu Lys Phe Ile Pro His
                 425                 430                 435

 Lys Asp Tyr Thr Ala Asn Arg Leu Val Ser Gly Leu Leu Gln Leu
                 440                 445                 450

 Pro Ser Asn Thr Ser Leu Val Ile Asp Glu Thr Leu Leu Glu Gln
                 455                 460                 465

 Gly Gln Leu Asp Thr Pro Gly Val His Asn Val Thr Ala Leu Ser
                 470                 475                 480

 Asn Leu Ile Thr Trp Gln Lys Val Asp Tyr Asp Phe Ser Tyr His
                 485                 490                 495

 Gln Met Glu Phe Pro Cys Asn Ile Asn Val Phe Ile Thr Ser Glu
                 500                 505                 510

 Gly Arg Ser Leu Leu Pro Ala Asp Cys Gln Ile His Leu Gln Pro
                 515                 520                 525

 Gln Leu Ile Pro Pro Asn Met Glu Glu Tyr Met Asn Ser Leu Leu
                 530                 535                 540

 Ser Ala Val Leu Pro Ser Val Leu Asn Lys Phe Arg Ile Tyr Leu
                 545                 550                 555

 Thr Leu Leu Arg Phe Leu Glu Tyr Ser Ile Ser Asp Glu Ile Thr
                 560                 565                 570

 Lys Ala Val Glu Asp Asp Phe Val Glu Met Arg Lys Asn Asp Pro
                 575                 580                 585

 Gln Ser Ile Thr Ala Asp Asp Leu His Gln Leu Leu Val Val Ala
                 590                 595                 600

 Arg Cys Leu Ser Leu Ser Ala Gly Gln Thr Thr Leu Ser Arg Glu
                 605                 610                 615

 Arg Trp Leu Arg Ala Lys Gln Leu Glu Ser Leu Arg Arg Thr Arg
                 620                 625                 630

 Leu Gln Gln Gln Lys Cys Val Asn Gly Asn Glu Leu
                 635                 640

<210> 3738
<211> 1723
<212> DNA
<213> Homo sapien

<400> 3738
 aagtttgcat tttcctctgt tcttgagccc agcttcttct cgtctcccac 50

 cccagcttcc cggcattgga agaagggacc gtcctcttcc ttgtcttggc 100

 cacccaaatc ctggtatcga aagggttgaa cggaccggaa gtgtgcagca 150

 gcgacgggtc cccagctaat cgacgccgga agtagcaatt actagacaag 200

 cattccgccg ccggcttcgc tatggcggca attcccccag attcctggca 250

 gccacccaac gtttacttgg agaccagcat gggaatcatt gtgctggagc 300

 tgtactggaa gcatgctcca aagacctgta agaactttgc tgagttggct 350

 cgtcgaggtt actacaatgg cacaaaattc cacagaatta tcaaagactt 400

 catgatccaa ggaggtgacc caacagggac aggtcgaggt ggtgcatcta 450

 tctatggcaa acagtttgaa gatgaacttc atccagactt gaaattcacg 500

 ggggctggaa ttctcgcaat ggccaatgcg gggccagata ccaatggcag 550

 ccagttcttt gtgaccctcg cccccaccca gtggcttgac ggcaaacaca 600

 ccatttttgg ccgagtgtgt cagggcatag gaatggtgaa tcgcgtggga 650

 atggtagaaa caaactccca ggaccgccct gtggacgacg tgaagatcat 700

 taaggcatac ccttctgggt agacttgcta ccctcttgag cagctcttct 750

 gagatggccc cagtgaacca gcttctagat gacatagaat gacatgtaat 800

 gctaaatttc attttggctt tgcaagtcat gaagcttagg aggcctggca 850

 tcttgggtga gttagagatg gaagtacatt ttaataggat gcttcttttc 900

 tcttccccca gtgcctaggt tgccagagca tttgcacaaa tgcccctgtt 950

 tatcaatagg tgactactta ctacacatga accataatgc tgcttcttgt 1000

 gcatgtctgc tctgatatac gtcgaacaat gtagcagcca ctgtcatttc 1050

 tcagtggttt tgcctaacca aacttcttcc taaggagatt tatattctgg 1100

 cctacacagc agtccttgat ggctgacagc cacagaattc caaaccaagt 1150

 agtgtctgtc agccctctta actctgtgca cgccctattt cagtctttta 1200

 catttgttct tctagggaat gtatgcatct ctatatatat tttccctctc 1250

 aaaaccagaa catcaacagt gctgtttctg acacttcaga catcccacgc 1300

 aaagccacat tgaatttttg ccaaatgaaa aacacatcca acaatcaagt 1350

 ttctaagaag gtgtcaagtg gggaataata ataatgtata ataatcaaga 1400

 aattagttta ttaaaaggaa gcagaagcat tgaccatttt ttcccagaga 1450

 agaggagaaa tctgtagtga gcaaaggaca gaccatgaat cctccttgag 1500

 aagtagtact ctcagaaagg agaagcgcca ctcaagttct tttaacccaa 1550

 gactttagag aaattaggtc caagattttt atatgttcag ttgtttatgt 1600

 ataaaaataa ctttctggat tttgtgggga ggagcaggag aggaaggaag 1650

 ttaataccta tgtaatacat agaaacttcc acaataaaat gccattgatg 1700

 gttgaaaaaa aaaaaaaaaa aaa 1723

<210> 3739
<211> 166
<212> PRT
<213> Homo sapien

<400> 3739
 Met Ala Ala Ile Pro Pro Asp Ser Trp Gln Pro Pro Asn Val Tyr
   1               5                  10                  15

 Leu Glu Thr Ser Met Gly Ile Ile Val Leu Glu Leu Tyr Trp Lys
                  20                  25                  30

 His Ala Pro Lys Thr Cys Lys Asn Phe Ala Glu Leu Ala Arg Arg
                  35                  40                  45

 Gly Tyr Tyr Asn Gly Thr Lys Phe His Arg Ile Ile Lys Asp Phe
                  50                  55                  60

 Met Ile Gln Gly Gly Asp Pro Thr Gly Thr Gly Arg Gly Gly Ala
                  65                  70                  75

 Ser Ile Tyr Gly Lys Gln Phe Glu Asp Glu Leu His Pro Asp Leu
                  80                  85                  90

 Lys Phe Thr Gly Ala Gly Ile Leu Ala Met Ala Asn Ala Gly Pro
                  95                 100                 105

 Asp Thr Asn Gly Ser Gln Phe Phe Val Thr Leu Ala Pro Thr Gln
                 110                 115                 120

 Trp Leu Asp Gly Lys His Thr Ile Phe Gly Arg Val Cys Gln Gly
                 125                 130                 135

 Ile Gly Met Val Asn Arg Val Gly Met Val Glu Thr Asn Ser Gln
                 140                 145                 150

 Asp Arg Pro Val Asp Asp Val Lys Ile Ile Lys Ala Tyr Pro Ser
                 155                 160                 165

 Gly


<210> 3740
<211> 2112
<212> DNA
<213> Homo sapien

<400> 3740
 ggtcgggacc ggcaagatgg cggcgcggac agcgttcggt gctgtgtgcc 50

 ggcgcctctg gcagggattg gggaattttt ctgtaaacac ttctaagggc 100

 aatacagcca aaaatggtgg cttgcttctc agtaccaata tgaagtgggt 150

 acagttttca aacctacacg ttgatgttcc aaaggatttg accaaacctg 200

 tggtaacaat ctctgatgaa ccagacatat tatataagcg cctctcggtt 250

 ttggtgaaag gtcacgataa ggctgtattg gacagttatg aatattttgc 300

 tgtgcttgct gctaaagaac ttggtatctc tattaaagta catgaacctc 350

 caaggaaaat agagcgattt actcttctcc aatcagtgca tatttacaag 400

 aagcacagag ttcagtatga aatgagaaca ctttacagat gtttagagtt 450

 agaacatcta actggaagca cagcagatgt ctacttggaa tatattcagc 500

 gaaacttacc tgaaggggtt gccatggaag taacaaagac acaattagaa 550

 cagttaccag aacacatcaa ggagccaatc tgggaaacac tatcagaaga 600

 aaaagaagaa agcaagtcat aaagcctcag ggaggccatt tttgcctaaa 650

 tttgaaatga gggtgggcca gatgagtatg tttaagtgga gagtgcttcc 700

 agctgagatg atttgagtct gtcctaactg ctccattgag ttctcgtgcc 750

 ctcatcagct gagggcaggg aatggaactt taatggaaga accactttta 800

 tctattcttt ttattcattg tttcagttct gatttcagca aacatgagca 850

 aaccactttg actgaaagca gaaagagtga aaattctatt ttgttacgct 900

 actggtgttc aattattagt ttgtaccatt tttaatttat gtcagttgat 950

 gcatctgaaa ataagtgctt ggagtgttcg tacccttatt tttttttaag 1000

 attcctagaa ggaatctttg gttaattcag attgagcagt taaagttttt 1050

 gctatttacc tttgtgcagg ctggcatatg ctaatttggg ggtggtaacc 1100

 aaccgatttt atctcatgta agcattacat tttgaagact gaatatactt 1150

 cacagcagat caaacacatt tatggcatgc actgacctct tcttggagcc 1200

 cagaacttta tagagttgcc taccagggtt actgtaatgg aatttatgat 1250

 cttaagaaat tactagttgt attatttatc ctatgattca ttcattcaat 1300

 aagcttttac tgcataaact ttacatccag cactgtagtt aagtacccaa 1350

 aattgaatag aaataatggc ttttgaaaat tgcacaaagc aggccaggca 1400

 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcaggcgg 1450

 atcacgaggt caagagatcc agaccatcct ggctaacacg gtgaaacccc 1500

 gtctctaata aaaatacaaa aattagctgg acatggtggc acgtgcctgt 1550

 aatcccagct actcaggagg ctgaggcagg agaatcgcgt gaacccgggc 1600

 ccggtggagg ctgcagtgag acgagatcgc gccactgcac tccagcctgg 1650

 cgacagagcg agacaccgtc tcaaaaaaaa aaaaaaagaa aattgtgcaa 1700

 agcataggta aatatttttc tttattaagc ttctcactga gaagccctct 1750

 ttattttggt aaatgtcact ctgtttgtta ggagatgtct gcttttccat 1800

 gaaatgaaat agtggctaaa gccctgaaag aggcaagact acaatgggct 1850

 gaaacagttg gtatagcaac cccagagaag tgcttcattt tctttttata 1900

 gtagaagcag gtccatgtct tttgtggttt cctgcacatc tttggagtag 1950

 ttatgacttc tcagtttttc cccccttaaa ctgcattgcc tattcttttt 2000

 tcctgacatg ctatcaggta tcagtgtgtt gaatacataa tgcttgtgta 2050

 tcagacttac gttactgtca tcaccattaa aagaattgca gccttgtgcc 2100

 ccatgacctt ca 2112

<210> 3741
<211> 201
<212> PRT
<213> Homo sapien

<400> 3741
 Met Ala Ala Arg Thr Ala Phe Gly Ala Val Cys Arg Arg Leu Trp
   1               5                  10                  15

 Gln Gly Leu Gly Asn Phe Ser Val Asn Thr Ser Lys Gly Asn Thr
                  20                  25                  30

 Ala Lys Asn Gly Gly Leu Leu Leu Ser Thr Asn Met Lys Trp Val
                  35                  40                  45

 Gln Phe Ser Asn Leu His Val Asp Val Pro Lys Asp Leu Thr Lys
                  50                  55                  60

 Pro Val Val Thr Ile Ser Asp Glu Pro Asp Ile Leu Tyr Lys Arg
                  65                  70                  75

 Leu Ser Val Leu Val Lys Gly His Asp Lys Ala Val Leu Asp Ser
                  80                  85                  90

 Tyr Glu Tyr Phe Ala Val Leu Ala Ala Lys Glu Leu Gly Ile Ser
                  95                 100                 105

 Ile Lys Val His Glu Pro Pro Arg Lys Ile Glu Arg Phe Thr Leu
                 110                 115                 120

 Leu Gln Ser Val His Ile Tyr Lys Lys His Arg Val Gln Tyr Glu
                 125                 130                 135

 Met Arg Thr Leu Tyr Arg Cys Leu Glu Leu Glu His Leu Thr Gly
                 140                 145                 150

 Ser Thr Ala Asp Val Tyr Leu Glu Tyr Ile Gln Arg Asn Leu Pro
                 155                 160                 165

 Glu Gly Val Ala Met Glu Val Thr Lys Thr Gln Leu Glu Gln Leu
                 170                 175                 180

 Pro Glu His Ile Lys Glu Pro Ile Trp Glu Thr Leu Ser Glu Glu
                 185                 190                 195

 Lys Glu Glu Ser Lys Ser
                 200

<210> 3742
<211> 5008
<212> DNA
<213> Homo sapien

<400> 3742
 ggcgcgggga ccgggctgtc tgaggtgcgc gccgcgctgg ggctcgcgct 50

 ctacctgatc gcgctgcgga cgctggtgca gctctcgctg cagcagctcg 100

 tgctacgcgg ggccgctgga caccgcgggg agttcgacgc gctccaagcc 150

 agggattatc ttgaacacat aacctccatt ggccccagga ctacaggaag 200

 tccagaaaat gaaattctga ccgtgcacta ccttttggaa cagattaaac 250

 tgattgaagt gcaaagcaac agccttcata agatttcagt agatgtacaa 300

 cggcccacag gctcttttag cattgatttc ttgggaggtt ttacaagcta 350

 ttatgacaac atcaccaatg ttgtggtaaa gctggaaccc agagatggag 400

 cccagcatgc tgtcttggct aattgtcatt ttgactcagt agcaaactca 450

 ccaggccagt catggtttca ttactcagca cccctgggct agcttgattc 500

 gtgcattcat taacctagag gcagcaggtg taggagggaa agaacttgta 550

 ttccaaacag gtcctgaaaa tccttggttg gttcaagctt atgtttcagc 600

 agctaaacac ccttttgctt ctgtggtggc tcaggaggtt tttcagagtg 650

 gaatcattcc ttcagatact gactttcgta tctacaggga ttttgggaac 700

 attccaggaa tagacttagc ttttattgag aatggataca tttatcacac 750

 caagtatgac acagcggaca gaattctaac agattccatt cagagagcag 800

 gtgacaacat tttagcagtt cttaagcatc tagctacatc tgatatgctg 850

 gctgctgctt ctaagtatcg acatggaaac atggtcttct ttgatgtgct 900

 gggcctgttt gtcattgcct acccctctcg tattggctca atcataaact 950

 acatggtggt aatgggtgtt gttttgtacc tgggcaaaaa atttttgcag 1000

 cccaaacata agactggtaa ctacaagaag gacttcttgt gtggacttgg 1050

 catcactttg atcagctggt tcactagcct tgttaccgtt ctcattatag 1100

 cagtgttcat ctctcttatt ggacagtctc tctcatggta taaccacttc 1150

 tatgtctccg tttgtctgta tggaactgca actgtagcca aaataatact 1200

 tatacatact cttgcgaaaa gattttatta catgaatgcc agtgcccagt 1250

 atctgggaga agtatttttt gacatttcgc tgtttgtcca ttgctgtttt 1300

 cttgttaccc tcacttacca aggactttgc tcggcgttta ttagtgctgt 1350

 ctgggtagca ttcccattgc tcacaaagct ctgtgtgcat aaggacttca 1400

 agcagcatgg tgcccaagga aaatttattg ctttttacct tttggggatg 1450

 tttattcctt atctttatgc attgtacctc atctgggcag tatttgagat 1500

 gtttacccct atcctcggga gaagtggttc tgaaatccca cctgatgttg 1550

 tgctggcatc cattttggct ggctgtacaa tgattctctc gtcctatttt 1600

 attaacttca tctaccttgc caagagcaca aaaaaaacca tgctaacttt 1650

 aactttggta tgtgcaatta cattcctcct tgtttgcagt ggaacatttt 1700

 ttccatatag ctccaatcct gctaatccga agccaaagag agtgtttctt 1750

 cagcatatga ctagaacatt ccatgacttg gaaggaaatg cagttaaacg 1800

 ggactctgga atatggatca atgggtttga ttatactgga atttctcaca 1850

 taacccctca cattcctgag atcaatgata gtatccgagc tcactgtgag 1900

 gagaatgcac ctctttgtgg ttttccttgg tatcttccag tgcactttct 1950

 gatcaggaaa aactggtatc ttcctgcccc agaagtttct ccaagaaatc 2000

 ctcctcattt ccgactcata tccaaagaac agacaccttg ggattctata 2050

 aaattgactt ttgaagcaac aggaccaagc catatgtcct tctatgttcg 2100

 agcccacaaa gggtcaacac tttctcagtg gtctcttggc aatggcaccc 2150

 cagtcacaag taaaggagga gactactttg tcttttactc ccatggactc 2200

 caggcctctg catggcagtt ctggatagaa gtgcaggttt cagaagaaca 2250

 tcctgaagga atggtcaccg tggccattgc tgcccactat ctgtctgggg 2300

 aagacaagag atcccctcaa ctggatgctc tgaaggaaaa gttcccagat 2350

 tggacatttc cctctgcctg ggtgtgcacc tacgatctct ttgtatttta 2400

 atcttgtgga tgagctctaa gtacatgccc agtggatact ccatgtgaca 2450

 tggtttctcc ctatgttacg tggatgtttg taacgtaagt caatgaattt 2500

 taatgatcat atgttcaaag agctttctgg gttaacgctt ttcagggcca 2550

 agcactataa gggtttagct gtggcgcagt gatgcatggc ctgttgacac 2600

 ttgaaaatgc cagtcttttg gcacttcagc acatgtgggt actgccacta 2650

 cacacacgtc attttatatg accttaagga caaagccaac aatccacttc 2700

 aatagctgcc cctttaggat caagaaagat gtacactgtc agagcattgt 2750

 taatgagaca aaagttgttt ccaatttaag ccccaaaacc atttgttgta 2800

 ttagtggatg gtgggtaaaa tatcattcac tgaggtaatg attccccttg 2850

 agaatataac tctgtgtagg tcactggaaa gtgattgcca tagggctggg 2900

 agagaagcat tgcactcttg aggctgtagc ctgtgtcaag ctgtttcttc 2950

 aggcagcctc tcaaatgtgc tttgtctctc tgtgctgagg cctggaccct 3000

 gtgctgagct ggtgactcac tgtcctgaca agtggacaca cagatgcact 3050

 gctgtgctgc tttcctgagg tggttttcta tgcctgtttt cctctgaaac 3100

 atgtctgtta cccctctcca tcttaccaag ttgaaaaggg gaatatttgg 3150

 ccacataccc ctctggtttt cgtaggttct tttggttcag aatattgttt 3200

 gtgccagtac atgaccttaa cttccttcct cagagcactg agctgccatc 3250

 tgggctattc tggggtagaa ggaaggctgg gagtggtggg aattttataa 3300

 atatttattc tcttttcttt gtttcatagg agtcttgtgt tatacaaggt 3350

 tagtccttca tggtataatc ttactgatgc actgggccta tctttttgtt 3400

 ttccagccag ttgaatagat tagtttttct cagtaactta ctatccagca 3450

 gactggcttt cctgagactt gaggttgtgg cttatactgg aatgagacca 3500

 ctgtacgtgt aggtggttca gatcctgcgt aatggcagca tgaggactta 3550

 aaaggtggtt ttcattttga agatggctat gtagcttgta aggtgtatca 3600

 cagcagtacc tctcatggct ttttggttcc agcagtgagg gcattggtga 3650

 gatcaatggt aaactgtgca agctttcttt ttatcattag gaaatgtgaa 3700

 acgttggaca aattttgagt tttaacaagg acaaaaagtt gaaagaaaag 3750

 gcacagttaa caaaaaaggg tggctagatt tatcttgggt gatggaggaa 3800

 atgagagagg aatgctcttg aaaggtggtc tgtggatctg tctgaataga 3850

 aagagcacag taagtatgca ttgccggaga aaacgtcctt gaagctgctt 3900

 gtctcatgtg tatgatgtgc tttttaaatc atgcccctcg ttgcctgcct 3950

 aatctgtgac tccctaaaaa ctaactgggc ccatgtagat ggggctgcaa 4000

 ccagagctga ataacatgtt aggctcacac atgcatcagc actgcacact 4050

 ggaatcattg ctcttcctgg actttgtaga aatcagtctc aagtgcttca 4100

 agagtctggc tcctgctact tttatctgtc aggtagcaca taaggtttgc 4150

 agggtttata ttttgtatag aatcacagtt gtggagaaaa agtaataatt 4200

 tctcaatgaa ttttaaaaat gggcctattt tctatccccg tggttcatct 4250

 gatataatta gtgttccctg tgaattcccc ccctctatgg gaaggatgcc 4300

 tttactcttt atcagtaata aattatgact gttttcatat tgccttaggg 4350

 ttatttccct gtgtaaacca ttgtcttttg ttttggtttt ctttagcatt 4400

 atgaagcttt ggtattgtac aaggtcagta gtaagatgct cactagtctc 4450

 agggcttgtg taatattctg ggaggtcatt taaatgccag aaatggtcaa 4500

 gcaattatac acagtattta tgactctgtt aagcataccg tttgtctgtc 4550

 acattagtag attctgagat taaaaaaaat ttttaaagag tgatcattta 4600

 aataatttct aaaagggtct tttcaagctc taacaaagtc actaacaaat 4650

 gcattatttt ctacagaatt agatgttagt agtacagtac tgcatattca 4700

 gggaaaaagt gtgaggaatt gatttcaaaa tagttcgttc ttgtgtttga 4750

 cctaagaatg attgtcgcat gaagtgtttg tttttacagt ttagcatata 4800

 taaacaaaca tgataggatt ccttaagatg ttaccaccca gggggccaca 4850

 agccagcctg ctgtctcagg aagctgtaga aggagtgttt gtcaatttct 4900

 tgtcactggt ttgctgactt actgaggatt aattgttgcc ttacaatgtt 4950

 actgaaataa actgtttaat ataaaaaaaa aaaaaaaaaa aaaaaaaaaa 5000

 aaaaaaaa 5008

<210> 3743
<211> 799
<212> PRT
<213> Homo sapien

<400> 3743
 Gly Ala Gly Thr Gly Leu Ser Glu Val Arg Ala Ala Leu Gly Leu
   1               5                  10                  15

 Ala Leu Tyr Leu Ile Ala Leu Arg Thr Leu Val Gln Leu Ser Leu
                  20                  25                  30

 Gln Gln Leu Val Leu Arg Gly Ala Ala Gly His Arg Gly Glu Phe
                  35                  40                  45

 Asp Ala Leu Gln Ala Arg Asp Tyr Leu Glu His Ile Thr Ser Ile
                  50                  55                  60

 Gly Pro Arg Thr Thr Gly Ser Pro Glu Asn Glu Ile Leu Thr Val
                  65                  70                  75

 His Tyr Leu Leu Glu Gln Ile Lys Leu Ile Glu Val Gln Ser Asn
                  80                  85                  90

 Ser Leu His Lys Ile Ser Val Asp Val Gln Arg Pro Thr Gly Ser
                  95                 100                 105

 Phe Ser Ile Asp Phe Leu Gly Gly Phe Thr Ser Tyr Tyr Asp Asn
                 110                 115                 120

 Ile Thr Asn Val Val Val Lys Leu Glu Pro Arg Asp Gly Ala Gln
                 125                 130                 135

 His Ala Val Leu Ala Asn Cys His Phe Asp Ser Val Ala Asn Ser
                 140                 145                 150

 Pro Gly Gln Ser Trp Phe His Tyr Ser Ala Pro Leu Gly Ser Leu
                 155                 160                 165

 Ile Arg Ala Phe Ile Asn Leu Glu Ala Ala Gly Val Gly Gly Lys
                 170                 175                 180

 Glu Leu Val Phe Gln Thr Gly Pro Glu Asn Pro Trp Leu Val Gln
                 185                 190                 195

 Ala Tyr Val Ser Ala Ala Lys His Pro Phe Ala Ser Val Val Ala
                 200                 205                 210

 Gln Glu Val Phe Gln Ser Gly Ile Ile Pro Ser Asp Thr Asp Phe
                 215                 220                 225

 Arg Ile Tyr Arg Asp Phe Gly Asn Ile Pro Gly Ile Asp Leu Ala
                 230                 235                 240

 Phe Ile Glu Asn Gly Tyr Ile Tyr His Thr Lys Tyr Asp Thr Ala
                 245                 250                 255

 Asp Arg Ile Leu Thr Asp Ser Ile Gln Arg Ala Gly Asp Asn Ile
                 260                 265                 270

 Leu Ala Val Leu Lys His Leu Ala Thr Ser Asp Met Leu Ala Ala
                 275                 280                 285

 Ala Ser Lys Tyr Arg His Gly Asn Met Val Phe Phe Asp Val Leu
                 290                 295                 300

 Gly Leu Phe Val Ile Ala Tyr Pro Ser Arg Ile Gly Ser Ile Ile
                 305                 310                 315

 Asn Tyr Met Val Val Met Gly Val Val Leu Tyr Leu Gly Lys Lys
                 320                 325                 330

 Phe Leu Gln Pro Lys His Lys Thr Gly Asn Tyr Lys Lys Asp Phe
                 335                 340                 345

 Leu Cys Gly Leu Gly Ile Thr Leu Ile Ser Trp Phe Thr Ser Leu
                 350                 355                 360

 Val Thr Val Leu Ile Ile Ala Val Phe Ile Ser Leu Ile Gly Gln
                 365                 370                 375

 Ser Leu Ser Trp Tyr Asn His Phe Tyr Val Ser Val Cys Leu Tyr
                 380                 385                 390

 Gly Thr Ala Thr Val Ala Lys Ile Ile Leu Ile His Thr Leu Ala
                 395                 400                 405

 Lys Arg Phe Tyr Tyr Met Asn Ala Ser Ala Gln Tyr Leu Gly Glu
                 410                 415                 420

 Val Phe Phe Asp Ile Ser Leu Phe Val His Cys Cys Phe Leu Val
                 425                 430                 435

 Thr Leu Thr Tyr Gln Gly Leu Cys Ser Ala Phe Ile Ser Ala Val
                 440                 445                 450

 Trp Val Ala Phe Pro Leu Leu Thr Lys Leu Cys Val His Lys Asp
                 455                 460                 465

 Phe Lys Gln His Gly Ala Gln Gly Lys Phe Ile Ala Phe Tyr Leu
                 470                 475                 480

 Leu Gly Met Phe Ile Pro Tyr Leu Tyr Ala Leu Tyr Leu Ile Trp
                 485                 490                 495

 Ala Val Phe Glu Met Phe Thr Pro Ile Leu Gly Arg Ser Gly Ser
                 500                 505                 510

 Glu Ile Pro Pro Asp Val Val Leu Ala Ser Ile Leu Ala Gly Cys
                 515                 520                 525

 Thr Met Ile Leu Ser Ser Tyr Phe Ile Asn Phe Ile Tyr Leu Ala
                 530                 535                 540

 Lys Ser Thr Lys Lys Thr Met Leu Thr Leu Thr Leu Val Cys Ala
                 545                 550                 555

 Ile Thr Phe Leu Leu Val Cys Ser Gly Thr Phe Phe Pro Tyr Ser
                 560                 565                 570

 Ser Asn Pro Ala Asn Pro Lys Pro Lys Arg Val Phe Leu Gln His
                 575                 580                 585

 Met Thr Arg Thr Phe His Asp Leu Glu Gly Asn Ala Val Lys Arg
                 590                 595                 600

 Asp Ser Gly Ile Trp Ile Asn Gly Phe Asp Tyr Thr Gly Ile Ser
                 605                 610                 615

 His Ile Thr Pro His Ile Pro Glu Ile Asn Asp Ser Ile Arg Ala
                 620                 625                 630

 His Cys Glu Glu Asn Ala Pro Leu Cys Gly Phe Pro Trp Tyr Leu
                 635                 640                 645

 Pro Val His Phe Leu Ile Arg Lys Asn Trp Tyr Leu Pro Ala Pro
                 650                 655                 660

 Glu Val Ser Pro Arg Asn Pro Pro His Phe Arg Leu Ile Ser Lys
                 665                 670                 675

 Glu Gln Thr Pro Trp Asp Ser Ile Lys Leu Thr Phe Glu Ala Thr
                 680                 685                 690

 Gly Pro Ser His Met Ser Phe Tyr Val Arg Ala His Lys Gly Ser
                 695                 700                 705

 Thr Leu Ser Gln Trp Ser Leu Gly Asn Gly Thr Pro Val Thr Ser
                 710                 715                 720

 Lys Gly Gly Asp Tyr Phe Val Phe Tyr Ser His Gly Leu Gln Ala
                 725                 730                 735

 Ser Ala Trp Gln Phe Trp Ile Glu Val Gln Val Ser Glu Glu His
                 740                 745                 750

 Pro Glu Gly Met Val Thr Val Ala Ile Ala Ala His Tyr Leu Ser
                 755                 760                 765

 Gly Glu Asp Lys Arg Ser Pro Gln Leu Asp Ala Leu Lys Glu Lys
                 770                 775                 780

 Phe Pro Asp Trp Thr Phe Pro Ser Ala Trp Val Cys Thr Tyr Asp
                 785                 790                 795

 Leu Phe Val Phe


<210> 3744
<211> 3455
<212> DNA
<213> Homo sapien

<400> 3744
 tgtgaagtca actttatccc agacagttcc atccaaggga gaattaagta 50

 gagaaatttg tctgcaatct caatctaaag acaaatctac gacaccagga 100

 ggaacaggaa ttaagccttt cctggaacgc tttggagagc gttgtcaaga 150

 acatagcaaa gaaagtccag ctcgtagcac accccacaga acccccatta 200

 ttactccaaa tacaaaggcc atccaagaaa gattattcaa gcaagacaca 250

 tcttcatcta ctacccattt agcacaacag ctcaagcagg aacgtcaaaa 300

 agaactagca tgtcttcgtg gccgatttga caagggcaat atatggagtg 350

 cagaaaaagg cggaaactca aaaagcaaac aactagaaac caaacaggaa 400

 actcactgtc agagcactcc cctcaaaaaa caccaaggtg tttcaaaaac 450

 tcagtcactt ccagtaacag aaaaggtgac cgaaaaccag ataccagcca 500

 aaaattctag tacagaacct aaagaagtga tacgtgaaat tgagatgagt 550

 gtggatgatg atgatatcaa tagttcgaaa gtaattaatg acctcttcag 600

 tgatgtccta gaggaaggtg aactagatat ggagaagagc caagaggaga 650

 tggatcaagc attagcagaa agcagcgaag aacaggaaga tgcactgaat 700

 atctcctcaa tgtctttact tgcaccattg gcacaaacag ttggtgtggt 750

 aagtccagag agttcagtgt ccacacctag actggaattg aaagacacca 800

 gcagaagtga tgaaagtcca aaaccaggaa aattccaaag aactcgtgtc 850

 cctcgagctg aatctggtga tagccttggt tctgaagatc gtgatcttct 900

 ttacagcatt gatgcatata gatctcaaag attcaaagaa acagaacgtc 950

 catcaataaa gcaggtgatt gttcggaagg aagatgttac ttcaaaactg 1000

 gatgaaaaaa ataatgcctt tccttgtcaa gttaatatca aacagaaaat 1050

 gcaggaactc aataacgaaa taaatatgca acagacagtg atctatcaag 1100

 ctagccaggc tcttaactgc tgtgttgatg aagaacatgg aaaagggtcc 1150

 ctagaagaag ctgaagcaga aagacttctt ctaattgcaa ctgggaagag 1200

 aacacttttg attgatgaat tgaataaatt gaagaacgaa ggacctcaga 1250

 ggaagaataa ggctagtccc caaagtgaat ttatgccatc caaaggatca 1300

 gttactttgt cagaaatccg cttgcctcta aaagcagatt ttgtctgcag 1350

 tacggttcag aaaccagatg cagcaaatta ctattactta attatactaa 1400

 aagcaggagc tgaaaatatg gtagccacac cattagcaag tacttcaaac 1450

 tctcttaacg gtgatgctct gacattcact actacattta ctctgcaaga 1500

 tgtatccaat gactttgaaa taaatattga agtttacagc ttggtgcaaa 1550

 agaaagatcc ctcaggcctt gataagaaga aaaaaacatc caagtccaag 1600

 gctattactc caaagcgact cctcacatct ataaccacaa aaagcaacat 1650

 tcattcttca gtcatggcca gtccaggagg tcttagtgct gtgcgaacca 1700

 gcaacttcgc ccttgttgga tcttacacat tatcattgtc ttcagtagga 1750

 aatactaagt ttgttctgga caaggtcccc tttttatctt ctttggaagg 1800

 tcatatttat ttaaaaataa aatgtcaagt gaattccagt gttgaagaaa 1850

 gaggttttct aaccatattt gaagatgtta gtggttttgg tgcctggcat 1900

 cgaagatggt gtgttctttc tggaaactgt atatcttatt ggacttatcc 1950

 agatgatgag aaacgcaaga atcccatagg aaggataaat ctggctaatt 2000

 gtaccagtcg tcagatagaa ccagccaaca gagaattttg tgcaagacgc 2050

 aacacttttg aattaattac tgtccgacca caaagagaag atgaccggga 2100

 gactcttgtc agccaatgca gggacacact ctgtgttacc aagaactggc 2150

 tgtctgcaga tactaaagaa gagcgggatc tctggatgca aaaactcaat 2200

 caagttcttg ttgatattcg cctctggcaa cctgatgctt gctacaaacc 2250

 tattggaaag ccttaaaccg ggaaatttcc atgctatcta gaggtttttg 2300

 atgtcatctt aagaaacaca cttaagagca tcagatttac tgattgcatt 2350

 ttatgcttta agtacgaaag ggtttgtgcc aatattcact acgtattatg 2400

 cagtatttat atcttttgta tgtaaaactt taactgattt ctgtcattca 2450

 tcaatgagta gaagtaaata cattatagtt gattttgcta aatcttaatt 2500

 taaaagcctc attttcctag aaatctaatt attcagttat tcatgacaat 2550

 atttttttaa aagtaagaaa ttctgagttg tcttcttgga gctgtaggtc 2600

 ttgaagcagc aacgtctttc aggggttgga gacagaaacc cattctccaa 2650

 tctcagtagt tttttcgaaa ggctgtgatc atttattgat cgtgatatga 2700

 cttgttacta gggtactgaa aaaaatgtct aaggccttta cagaaacatt 2750

 tttagtaatg aggatgagaa ctttttcaaa tagcaaatat atattggctt 2800

 aaagcatgag gctgtcttca gaaaagtgat gtggacatag gaggcaatgt 2850

 gtgagacttg ggggttcaat attttatata gaagagttaa taagcacatg 2900

 gtttacattt actcagctac tatatatgca gtgtggtgca cattttcaca 2950

 gaattctggc ttcattaaga tcattatttt tgctgcgtag cttacagact 3000

 tagcatatta gttttttcta ctcctacaag tgtaaattga aaaatcttta 3050

 tattaaaaaa gtaaactgtt atgaagctgc tatgtactaa taatactttg 3100

 cttgccaaag tgtttgggtt ttgttgttgt ttgtttgttt gtttgttttt 3150

 ggttcatgaa caacagtgtc tagaaaccca ttttgaaagt ggaaaattat 3200

 taagtcacct atcaccttta aacgcctttt tttaaaatta taaaatattg 3250

 taaagcaggg tctcaacttt taaatacact ttgaacttct tctctgaatt 3300

 attaaagttc tttatgacct catttataaa cactaaattc tgtcacctcc 3350

 tgtcatttta ttttttattc attcaaatgt attttttctt gtgcatatta 3400

 taaaaatata ttttatgagc tcttactcaa ataaatacct gtaaatgtct 3450

 aaagg 3455

<210> 3745
<211> 573
<212> PRT
<213> Homo sapien

<400> 3745
 Met Ser Val Asp Asp Asp Asp Ile Asn Ser Ser Lys Val Ile Asn
   1               5                  10                  15

 Asp Leu Phe Ser Asp Val Leu Glu Glu Gly Glu Leu Asp Met Glu
                  20                  25                  30

 Lys Ser Gln Glu Glu Met Asp Gln Ala Leu Ala Glu Ser Ser Glu
                  35                  40                  45

 Glu Gln Glu Asp Ala Leu Asn Ile Ser Ser Met Ser Leu Leu Ala
                  50                  55                  60

 Pro Leu Ala Gln Thr Val Gly Val Val Ser Pro Glu Ser Ser Val
                  65                  70                  75

 Ser Thr Pro Arg Leu Glu Leu Lys Asp Thr Ser Arg Ser Asp Glu
                  80                  85                  90

 Ser Pro Lys Pro Gly Lys Phe Gln Arg Thr Arg Val Pro Arg Ala
                  95                 100                 105

 Glu Ser Gly Asp Ser Leu Gly Ser Glu Asp Arg Asp Leu Leu Tyr
                 110                 115                 120

 Ser Ile Asp Ala Tyr Arg Ser Gln Arg Phe Lys Glu Thr Glu Arg
                 125                 130                 135

 Pro Ser Ile Lys Gln Val Ile Val Arg Lys Glu Asp Val Thr Ser
                 140                 145                 150

 Lys Leu Asp Glu Lys Asn Asn Ala Phe Pro Cys Gln Val Asn Ile
                 155                 160                 165

 Lys Gln Lys Met Gln Glu Leu Asn Asn Glu Ile Asn Met Gln Gln
                 170                 175                 180

 Thr Val Ile Tyr Gln Ala Ser Gln Ala Leu Asn Cys Cys Val Asp
                 185                 190                 195

 Glu Glu His Gly Lys Gly Ser Leu Glu Glu Ala Glu Ala Glu Arg
                 200                 205                 210

 Leu Leu Leu Ile Ala Thr Gly Lys Arg Thr Leu Leu Ile Asp Glu
                 215                 220                 225

 Leu Asn Lys Leu Lys Asn Glu Gly Pro Gln Arg Lys Asn Lys Ala
                 230                 235                 240

 Ser Pro Gln Ser Glu Phe Met Pro Ser Lys Gly Ser Val Thr Leu
                 245                 250                 255

 Ser Glu Ile Arg Leu Pro Leu Lys Ala Asp Phe Val Cys Ser Thr
                 260                 265                 270

 Val Gln Lys Pro Asp Ala Ala Asn Tyr Tyr Tyr Leu Ile Ile Leu
                 275                 280                 285

 Lys Ala Gly Ala Glu Asn Met Val Ala Thr Pro Leu Ala Ser Thr
                 290                 295                 300

 Ser Asn Ser Leu Asn Gly Asp Ala Leu Thr Phe Thr Thr Thr Phe
                 305                 310                 315

 Thr Leu Gln Asp Val Ser Asn Asp Phe Glu Ile Asn Ile Glu Val
                 320                 325                 330

 Tyr Ser Leu Val Gln Lys Lys Asp Pro Ser Gly Leu Asp Lys Lys
                 335                 340                 345

 Lys Lys Thr Ser Lys Ser Lys Ala Ile Thr Pro Lys Arg Leu Leu
                 350                 355                 360

 Thr Ser Ile Thr Thr Lys Ser Asn Ile His Ser Ser Val Met Ala
                 365                 370                 375

 Ser Pro Gly Gly Leu Ser Ala Val Arg Thr Ser Asn Phe Ala Leu
                 380                 385                 390

 Val Gly Ser Tyr Thr Leu Ser Leu Ser Ser Val Gly Asn Thr Lys
                 395                 400                 405

 Phe Val Leu Asp Lys Val Pro Phe Leu Ser Ser Leu Glu Gly His
                 410                 415                 420

 Ile Tyr Leu Lys Ile Lys Cys Gln Val Asn Ser Ser Val Glu Glu
                 425                 430                 435

 Arg Gly Phe Leu Thr Ile Phe Glu Asp Val Ser Gly Phe Gly Ala
                 440                 445                 450

 Trp His Arg Arg Trp Cys Val Leu Ser Gly Asn Cys Ile Ser Tyr
                 455                 460                 465

 Trp Thr Tyr Pro Asp Asp Glu Lys Arg Lys Asn Pro Ile Gly Arg
                 470                 475                 480

 Ile Asn Leu Ala Asn Cys Thr Ser Arg Gln Ile Glu Pro Ala Asn
                 485                 490                 495

 Arg Glu Phe Cys Ala Arg Arg Asn Thr Phe Glu Leu Ile Thr Val
                 500                 505                 510

 Arg Pro Gln Arg Glu Asp Asp Arg Glu Thr Leu Val Ser Gln Cys
                 515                 520                 525

 Arg Asp Thr Leu Cys Val Thr Lys Asn Trp Leu Ser Ala Asp Thr
                 530                 535                 540

 Lys Glu Glu Arg Asp Leu Trp Met Gln Lys Leu Asn Gln Val Leu
                 545                 550                 555

 Val Asp Ile Arg Leu Trp Gln Pro Asp Ala Cys Tyr Lys Pro Ile
                 560                 565                 570

 Gly Lys Pro


<210> 3746
<211> 1510
<212> DNA
<213> Homo sapien

<400> 3746
 gcggcaatca tggcgccacc tgtgagatac tgcatccccg gcgaacgtct 50

 gtgtaacttg gaggagggca gcccgggcag cggcacctac acccgccacg 100

 gctacatctt ttcgtcgctt gccggctgtc tgatgaagag cagcgagaat 150

 ggcgcgcttc cagtggtgtc tgtagtgaga gaaacagagt cccagttact 200

 gccagatgtg ggagctattg taacctgtaa ggtctctagc atcaattcac 250

 gctttgccaa agtacacatc ctgtatgtgg ggtccatgcc tcttaagaac 300

 tcttttcgag gaactatccg caaggaagat gtccgagcaa ctgaaaaaga 350

 caaggttgaa atttataaga gtttccgccc aggtgacatt gtcttggcca 400

 aagtgatctc cttaggtgat gcacagtcca actacctgct aaccaccgcc 450

 gagaacgagc tgggagtggt ggtagcccac agtgagtcag gtatccagat 500

 ggttcccatc agctggtgtg agatgcagtg ccctaagacc cacactaaag 550

 aattccggaa agtagcccga gtacaacccg aattcttgca gacctaagaa 600

 gccacttttt accctatgga agggggtaag ctgttcctga gtataacacc 650

 aagatgctgc tgtctttatt caaacacctg gcgtcggcca acagccactt 700

 ccagaaaaat cttccagttt acgctgtaga tggaacatgt ttctgtgaac 750

 ctatcagtgg atttcattct cttgagtaat aaatcttatc ttttcaaggc 800

 accaacaaac aaaactgtga tattggaaat agcctatccc tcctgacagt 850

 ccttataaat acatattttt tgctatgata aaactttttt actaaaagga 900

 tgttatagag tctgttgtct taagcagaga aagacatcta aatggtgtca 950

 ggacatttca gtacttctgc ttattgagta cttactgtgc taggcactga 1000

 gtcaggtgct ttacatacgt ccccttcatt taggtacatt gtgatttaat 1050

 gaaaatttga ggacacgtgg tgatacagat agcatgtgag gcaggcatgg 1100

 tggctcatgt ttgtaaatcc cagcactttg ggaaggccga gttggttttg 1150

 aactcctggc ctcccaaggt gctgatagta caggcatgaa ccactgtgct 1200

 tggcctttta aaattttgta gagatgcagt cttactatgt tgcccaggct 1250

 gtctcaaact cctggcctca agtggtcctc ctgccttggc ctcccaaaat 1300

 gttgcaatta caggcatgag cactgtgctt ggcaagctaa ggaggatttt 1350

 cactagcagt ttcatttgac aataccaatc tagaggtgag cttctcaatc 1400

 tttaatgtgt atccaaatca cctggggaat agatgccgat tctgaaacag 1450

 gtctggagtg agacctgagg ttctgcatgt ataacaagct cccagggggt 1500

 ccagctgtca 1510

<210> 3747
<211> 195
<212> PRT
<213> Homo sapien

<400> 3747
 Met Ala Pro Pro Val Arg Tyr Cys Ile Pro Gly Glu Arg Leu Cys
   1               5                  10                  15

 Asn Leu Glu Glu Gly Ser Pro Gly Ser Gly Thr Tyr Thr Arg His
                  20                  25                  30

 Gly Tyr Ile Phe Ser Ser Leu Ala Gly Cys Leu Met Lys Ser Ser
                  35                  40                  45

 Glu Asn Gly Ala Leu Pro Val Val Ser Val Val Arg Glu Thr Glu
                  50                  55                  60

 Ser Gln Leu Leu Pro Asp Val Gly Ala Ile Val Thr Cys Lys Val
                  65                  70                  75

 Ser Ser Ile Asn Ser Arg Phe Ala Lys Val His Ile Leu Tyr Val
                  80                  85                  90

 Gly Ser Met Pro Leu Lys Asn Ser Phe Arg Gly Thr Ile Arg Lys
                  95                 100                 105

 Glu Asp Val Arg Ala Thr Glu Lys Asp Lys Val Glu Ile Tyr Lys
                 110                 115                 120

 Ser Phe Arg Pro Gly Asp Ile Val Leu Ala Lys Val Ile Ser Leu
                 125                 130                 135

 Gly Asp Ala Gln Ser Asn Tyr Leu Leu Thr Thr Ala Glu Asn Glu
                 140                 145                 150

 Leu Gly Val Val Val Ala His Ser Glu Ser Gly Ile Gln Met Val
                 155                 160                 165

 Pro Ile Ser Trp Cys Glu Met Gln Cys Pro Lys Thr His Thr Lys
                 170                 175                 180

 Glu Phe Arg Lys Val Ala Arg Val Gln Pro Glu Phe Leu Gln Thr
                 185                 190                 195

<210> 3748
<211> 1041
<212> DNA
<213> Homo sapien

<400> 3748
 gggcggcgat ggcggcggcg gaggccggtg gcgacgacgc ccgctgcgtg 50

 cggctgagcg ccgagcgggc acaggcgctg ctggccgacg tggacacgct 100

 gctgttcgac tgcgacggcg tgctgtggcg cggggagacc gccgtgcctg 150

 gcgcgcccga ggccctgcgg gcgctgcgag cccgcggcaa gcgcctgggc 200

 ttcatcacca acaacagcag caagacccgc gctgcctacg ccgagaagct 250

 gcggcgcctg ggcttcggcg gccccgcggg gcccggcgcc agcctggagg 300

 tcttcggcac ggcctactgc accgcgctct acctgcgcca gcgcctggcc 350

 ggcgcccccg cgcccaaggc ctacgtgctg ggcagcccag ccctggccgc 400

 ggagctggag gccgtgggcg tcgccagcgt gggcgtgggg cccgagccac 450

 tgcagggcga gggtcccggc gactggctgc acgcgccgct ggagcccgac 500

 gtgcgcgcgg tggtggtggg ctttgacccg cacttcagct acatgaagct 550

 caccaaggcc ctgcgctacc tgcagcagcc cggctgcctg ctcgtgggca 600

 ccaacatgga caaccggctt ccgcttgaga acggccgctt catcgcgggt 650

 accgggtgtc tggtccgagc cgtggagatg gccgcccagc gccaggccga 700

 catcatcggg aagcccagcc gcttcatttt cgactgcgtg tcccaggaat 750

 acggcatcaa ccccgagcgc accgtcatgg tgggagaccg cctggacaca 800

 gacatcctcc taggcgccac ctgtggcctg aagaccatcc tgaccctcac 850

 cggagtctcc actctagggg atgtgaagaa taatcaggaa agtgactgcg 900

 tgtctaagaa gaaaatggtc cctgacttct atgttgacag catagccgac 950

 cttttgcctg cccttcaagg ttaaagattg agtgtcttta atctgcagaa 1000

 taaaaaaaaa gaaattgaaa aaaaaaaaaa aaaaaaaaaa a 1041

<210> 3749
<211> 321
<212> PRT
<213> Homo sapien

<400> 3749
 Met Ala Ala Ala Glu Ala Gly Gly Asp Asp Ala Arg Cys Val Arg
   1               5                  10                  15

 Leu Ser Ala Glu Arg Ala Gln Ala Leu Leu Ala Asp Val Asp Thr
                  20                  25                  30

 Leu Leu Phe Asp Cys Asp Gly Val Leu Trp Arg Gly Glu Thr Ala
                  35                  40                  45

 Val Pro Gly Ala Pro Glu Ala Leu Arg Ala Leu Arg Ala Arg Gly
                  50                  55                  60

 Lys Arg Leu Gly Phe Ile Thr Asn Asn Ser Ser Lys Thr Arg Ala
                  65                  70                  75

 Ala Tyr Ala Glu Lys Leu Arg Arg Leu Gly Phe Gly Gly Pro Ala
                  80                  85                  90

 Gly Pro Gly Ala Ser Leu Glu Val Phe Gly Thr Ala Tyr Cys Thr
                  95                 100                 105

 Ala Leu Tyr Leu Arg Gln Arg Leu Ala Gly Ala Pro Ala Pro Lys
                 110                 115                 120

 Ala Tyr Val Leu Gly Ser Pro Ala Leu Ala Ala Glu Leu Glu Ala
                 125                 130                 135

 Val Gly Val Ala Ser Val Gly Val Gly Pro Glu Pro Leu Gln Gly
                 140                 145                 150

 Glu Gly Pro Gly Asp Trp Leu His Ala Pro Leu Glu Pro Asp Val
                 155                 160                 165

 Arg Ala Val Val Val Gly Phe Asp Pro His Phe Ser Tyr Met Lys
                 170                 175                 180

 Leu Thr Lys Ala Leu Arg Tyr Leu Gln Gln Pro Gly Cys Leu Leu
                 185                 190                 195

 Val Gly Thr Asn Met Asp Asn Arg Leu Pro Leu Glu Asn Gly Arg
                 200                 205                 210

 Phe Ile Ala Gly Thr Gly Cys Leu Val Arg Ala Val Glu Met Ala
                 215                 220                 225

 Ala Gln Arg Gln Ala Asp Ile Ile Gly Lys Pro Ser Arg Phe Ile
                 230                 235                 240

 Phe Asp Cys Val Ser Gln Glu Tyr Gly Ile Asn Pro Glu Arg Thr
                 245                 250                 255

 Val Met Val Gly Asp Arg Leu Asp Thr Asp Ile Leu Leu Gly Ala
                 260                 265                 270

 Thr Cys Gly Leu Lys Thr Ile Leu Thr Leu Thr Gly Val Ser Thr
                 275                 280                 285

 Leu Gly Asp Val Lys Asn Asn Gln Glu Ser Asp Cys Val Ser Lys
                 290                 295                 300

 Lys Lys Met Val Pro Asp Phe Tyr Val Asp Ser Ile Ala Asp Leu
                 305                 310                 315

 Leu Pro Ala Leu Gln Gly
                 320

<210> 3750
<211> 2064
<212> DNA
<213> Homo sapien

<400> 3750
 ctgttccaaa ccacgtggac gcgtctgggc tgctggaggc agcccgagcc 50

 gccgccgtcg gtgtcgccgc caccaccacc atcggagtca cgagtcccgc 100

 gtctgtccga agtcgccgct ctcgggctgc tcacgtctct tcggagagcg 150

 cgcacatggc gactcaggcg tactccctca gctacgcagg gtgcaacttc 200

 ttgcgccaac gtctggtcct gtctaccctg agcgggcgcc ccgtcaaaat 250

 ccgaaagatt cgggccagag acgacaaccc gggcctccga gattttgaag 300

 ccagcttcat aaggctattg gacaaaataa cgaatggttc tcgaattgaa 350

 ataaaccaaa caggaacaac cttatattat cagcctggcc tcctgtatgg 400

 tggatctgtg gaacatgact gtagcgtcct tcgtggcatt gggtattacc 450

 tggagagtct tctttgcttg gctccattta tgaagcaccc gttaaaaata 500

 gttctacgag gagtgaccaa tgatcaggtt gacccttcag ttgatgttct 550

 taaggcaaca gcactccctt tgttgaaaca atttgggatt gatggtgaat 600

 catttgaact gaatattgtg cgacggggaa tgcctcccgg aggaggaggc 650

 gaagtggttt tctcatgtcc tgtgaggaag gtcttgaagc ccattcaact 700

 cacagatcca ggaaaaatca aacgtattag aggaatggcg tactctgtac 750

 gtgtgtcacc tcagatggcg aaccggattg tggattctgc gaggagcatc 800

 ctcaacaagt tcatacctga tatctatatt tacacagatc acatgaaagg 850

 agtcaactct gggaagtctc cgggctttgg gttgtcactg gttgctgaga 900

 ccaccagtgg caccttcctc agtgctgaac tggcctccaa cccccagggc 950

 cagggagcag cagtacttcc agaggacctt ggcaggaact gtgcccggct 1000

 gctgctggag gaaatctaca ggggtggatg cgtagactcg accaaccaaa 1050

 gcctggcgct actactcatg acccttggac agcaggatgt ttccaaagtc 1100

 ctgctaggcc ctctctctcc ctacacgata gaatttttgc ggcatttgaa 1150

 gagctttttc cagattatgt ttaaaattga aaccaagcca tgtggtgaag 1200

 aactcaaggg tggggataaa gtgctgatga cctgtgttgg cattggtttc 1250

 tccaacctta gcaagaccct caagtgataa ccatcacaag ataaggcccc 1300

 agtgcctaca gacaaagcag aagctgccac ggacaccaat gggaccaagt 1350

 ccaaatggat taatccagga cagaatagcc acttgcttaa ttttctgtga 1400

 agaaatatca atatacaaat aaaagacatc cctgtagcat atggtttcca 1450

 gctgtttctc cagtggcatt gccattgccc aggaggggcc cagtcaccat 1500

 gagagctccc ttgccttacc tggaggaaga atgtgccttc aggccacagt 1550

 cgtgctgcta gaacagtctc atagctgcag ttcagctgtg cttcctcagc 1600

 ctactatcat aggcttcctc agccctctgt catatggctg ttttgcaaac 1650

 ctgtggagtc tgttactgtt ctttctgcaa ggactcacct ccttgagcct 1700

 tggtttttgt tgtagggatt aaatgagata atatgagtgg cagctcttca 1750

 tgagtcctgc agtgctaagc aaatgtcaga aattggtgta ttagactatt 1800

 tatctttgat cttctgaatg gattgctgtc atggacacgg acacggatct 1850

 tcatctggtt cattgtattt atatgtgagg gatggatggc tgcggggctc 1900

 caagtaagtt attgggatgt tttttatatt ccaggtgtgc tgtacattct 1950

 tattttattt tcacaacagc tctgtgatgt aaatgctatc tccatgagaa 2000

 aattcataaa gggtgttttg ttcctttgaa atgtataatg taaagacatt 2050

 aaatctcctc attt 2064

<210> 3751
<211> 373
<212> PRT
<213> Homo sapien

<400> 3751
 Met Ala Thr Gln Ala Tyr Ser Leu Ser Tyr Ala Gly Cys Asn Phe
   1               5                  10                  15

 Leu Arg Gln Arg Leu Val Leu Ser Thr Leu Ser Gly Arg Pro Val
                  20                  25                  30

 Lys Ile Arg Lys Ile Arg Ala Arg Asp Asp Asn Pro Gly Leu Arg
                  35                  40                  45

 Asp Phe Glu Ala Ser Phe Ile Arg Leu Leu Asp Lys Ile Thr Asn
                  50                  55                  60

 Gly Ser Arg Ile Glu Ile Asn Gln Thr Gly Thr Thr Leu Tyr Tyr
                  65                  70                  75

 Gln Pro Gly Leu Leu Tyr Gly Gly Ser Val Glu His Asp Cys Ser
                  80                  85                  90

 Val Leu Arg Gly Ile Gly Tyr Tyr Leu Glu Ser Leu Leu Cys Leu
                  95                 100                 105

 Ala Pro Phe Met Lys His Pro Leu Lys Ile Val Leu Arg Gly Val
                 110                 115                 120

 Thr Asn Asp Gln Val Asp Pro Ser Val Asp Val Leu Lys Ala Thr
                 125                 130                 135

 Ala Leu Pro Leu Leu Lys Gln Phe Gly Ile Asp Gly Glu Ser Phe
                 140                 145                 150

 Glu Leu Asn Ile Val Arg Arg Gly Met Pro Pro Gly Gly Gly Gly
                 155                 160                 165

 Glu Val Val Phe Ser Cys Pro Val Arg Lys Val Leu Lys Pro Ile
                 170                 175                 180

 Gln Leu Thr Asp Pro Gly Lys Ile Lys Arg Ile Arg Gly Met Ala
                 185                 190                 195

 Tyr Ser Val Arg Val Ser Pro Gln Met Ala Asn Arg Ile Val Asp
                 200                 205                 210

 Ser Ala Arg Ser Ile Leu Asn Lys Phe Ile Pro Asp Ile Tyr Ile
                 215                 220                 225

 Tyr Thr Asp His Met Lys Gly Val Asn Ser Gly Lys Ser Pro Gly
                 230                 235                 240

 Phe Gly Leu Ser Leu Val Ala Glu Thr Thr Ser Gly Thr Phe Leu
                 245                 250                 255

 Ser Ala Glu Leu Ala Ser Asn Pro Gln Gly Gln Gly Ala Ala Val
                 260                 265                 270

 Leu Pro Glu Asp Leu Gly Arg Asn Cys Ala Arg Leu Leu Leu Glu
                 275                 280                 285

 Glu Ile Tyr Arg Gly Gly Cys Val Asp Ser Thr Asn Gln Ser Leu
                 290                 295                 300

 Ala Leu Leu Leu Met Thr Leu Gly Gln Gln Asp Val Ser Lys Val
                 305                 310                 315

 Leu Leu Gly Pro Leu Ser Pro Tyr Thr Ile Glu Phe Leu Arg His
                 320                 325                 330

 Leu Lys Ser Phe Phe Gln Ile Met Phe Lys Ile Glu Thr Lys Pro
                 335                 340                 345

 Cys Gly Glu Glu Leu Lys Gly Gly Asp Lys Val Leu Met Thr Cys
                 350                 355                 360

 Val Gly Ile Gly Phe Ser Asn Leu Ser Lys Thr Leu Lys
                 365                 370

<210> 3752
<211> 1843
<212> DNA
<213> Homo sapien

<400> 3752
 ggcccttgaa ttccgcggaa cgaggtggtg ccaacgctgt gtttcaaccc 50

 ggtcactaaa catccgcgag catcctgtca gagctctcag ctcattggcg 100

 aaagtaaaac gccaaggaaa agcacctccc tttttgggcg tggaaagatg 150

 gcggtaaaag ccacaatgcg caggcgtcat cgctcacttc tcccctcccg 200

 gcttctgctc cacctgacgc ctgcgcagta agtaagcctg ccagacacgc 250

 tgtggcggct gcctgaagct agtgagtcgc ggcgccgcgc acttgtggtt 300

 gggtcagtgc cgcgcgccgc tcggtcgtta ccgcgaggcg ctggtggcct 350

 tcaggctgga cggcgcgggt cagccctggt ttgccggctt ctgggtcttt 400

 gaacagccgc gatgtcgatc ttcaccccca ccaaccagat ccgcctaacc 450

 aatgtggccg tggtacggat gaagcgcgcc aggaagcgct tcgaaatcgc 500

 ctgctacaga aacaaggtcg tcggctggcg gagcggcttg gaaaaagacc 550

 ttgatgaagt tctgcagacc cactcagtgt ttgtaaatgt ttcctaaggt 600

 caggttgcca agaaggaaga tctcatcagt gcgtttggaa cagatgacca 650

 aactgaaatc tattttgact aaaggagaag ttcaagtatc agataaagac 700

 acacacaact ggagcagatg tttagggaca ttgcaattat tgtggcagac 750

 aaatgtgtga ctcctgaaac aaagagacca tacaccgtga tccttattga 800

 gagagccatg aaggacatcc actatttggt gaaaaccaac aggagtacaa 850

 aacagcaggc tttggaagtg ataaagcagt taaaagagaa aatgaagata 900

 gaacgtgctc acatgaggct tcagttcatc cttccagtga atgaaggcaa 950

 gaagctgaaa gaaaagctca agccactgat caaggtcata gaaagtaaag 1000

 attatggcca acagttagaa atcgtatgtc tgattgacct gggctgcttc 1050

 cgagaaattg atgagctaat aaaaaaggaa accaaaggca aaggctcttt 1100

 ggaagtactc aatctgaaag atttgaagaa ggagatgaga aatttgaatg 1150

 acacccatca gtctcttcac ctctaaaaca ctaaagtgtt ttcgtttcca 1200

 acagcactgt ttcatgtctg tggtctgcca aatacttgct caaactattt 1250

 gacattttct atctttgtgt taacagtgga cacagcaagg ctttcctaca 1300

 taagtataat aatgtgggaa tgatttggtt ttaattataa actggggtct 1350

 aaatcctaaa gcaaaattga aactccagga tgcaaaatcc agagtggcat 1400

 tttgctactc tgtctcatgc cttgatagct ttccaaaatg aaagttactt 1450

 gaggcagctc ttgtgggtga aaagtttttt gtacagtaga gtaagattat 1500

 taggggtatg tctatacgac aaaagggggg tctttcctaa aaaagaaaac 1550

 atgatgcttc atttctactt aatggaactt gtgttctgag ggtcattatg 1600

 gtatcgtaat ataaagcttg gatgatgttc ctgattatct gagaaacaga 1650

 tatagaaaaa ttgtgtcgga cttaaataat tttcgttgaa catgctgcca 1700

 taacttagat tattcttggt taaaaaataa aagtcactta tttctaattc 1750

 ttaaagttta taatatatat taatatagct aaaattgtat gtaatcaata 1800

 aaaccactct tatgtttatt aaactatggc ttgtgtttct aga 1843

<210> 3753
<211> 122
<212> PRT
<213> Homo sapien

<400> 3753
 Met Lys Asp Ile His Tyr Leu Val Lys Thr Asn Arg Ser Thr Lys
   1               5                  10                  15

 Gln Gln Ala Leu Glu Val Ile Lys Gln Leu Lys Glu Lys Met Lys
                  20                  25                  30

 Ile Glu Arg Ala His Met Arg Leu Gln Phe Ile Leu Pro Val Asn
                  35                  40                  45

 Glu Gly Lys Lys Leu Lys Glu Lys Leu Lys Pro Leu Ile Lys Val
                  50                  55                  60

 Ile Glu Ser Lys Asp Tyr Gly Gln Gln Leu Glu Ile Val Cys Leu
                  65                  70                  75

 Ile Asp Leu Gly Cys Phe Arg Glu Ile Asp Glu Leu Ile Lys Lys
                  80                  85                  90

 Glu Thr Lys Gly Lys Gly Ser Leu Glu Val Leu Asn Leu Lys Asp
                  95                 100                 105

 Leu Lys Lys Glu Met Arg Asn Leu Asn Asp Thr His Gln Ser Leu
                 110                 115                 120

 His Leu


<210> 3754
<211> 3333
<212> DNA
<213> Homo sapien

<400> 3754
 cggcgccagc ggccgcacgc cgcggagcag gggctcggag gtcccgggat 50

 tacggtgctc gagcacgctg gtgggaaagg acccgggact tgaacagtgt 100

 tgtgcggcgc catgcaggtc tccagcctca atgaggtgaa gatttacagc 150

 ctcagctgcg gcaagtccct tcctgagtgg ctttctgata ggaagaagag 200

 agcgctacag aagaaagatg tagatgtccg taggagaatt gaacttattc 250

 aggactttga aatgcctact gtgtgtacca ctattaaggt gtcaaaagat 300

 ggacagtaca ttttagcaac tggaacatat aaacctcggg ttcgatgtta 350

 tgacacctat caattatcct tgaagtttga aaggtgttta gattcagaag 400

 ttgtcacctt tgaaattttg tctgatgact actcaaagat tgtcttctta 450

 cataatgata gatacattga atttcattcg caatcaggtt tttactacaa 500

 aaccagaata ccaaagtttg ggagagattt ctcttaccac tatccatcct 550

 gtgacttgta ctttgttggt gcaagttctg aagtttatag gttaaactta 600

 gaacaaggac gatacctgaa tcctctacaa actgatgctg cggagaataa 650

 tgtttgtgac ataaattcag tgcatggctt gtttgccaca ggaaccatag 700

 agggtagagt ggagtgctgg gacccaagaa ctcgaaacag agttggcctg 750

 ttagactgcg ccttaaacag tgtcacagca gattcagaga taaacagttt 800

 accaacaatc tctgctttga aatttaatgg tgccttgacc atggcagttg 850

 gaacaaccac agggcaggga aaaatattta cttccttgga gccagagcat 900

 gaccttaatg atgtttgtct ctaccccaac tcaggcatgc tcctgacggc 950

 caatgaaacc cccaagatgg gcatctatta cattccagtt ttgggtcctg 1000

 ctcctcggtg gtgttccttc ttagacaact tgaccgaaga attagaagag 1050

 aatccagaaa gcacagtcta tgatgattat aaatttgtca ccaagaaaga 1100

 ccttgaaaat ttagggctca cccacctcat tggatctcct ttcctccggg 1150

 catatatgca tgggtttttc atggatataa gactctatca caaggtgaaa 1200

 ctgatggtaa atccatttgc ttatgaagaa tataggaaag ataaaatacg 1250

 acagaaaata gaagaaacac gtgcacagag agtccagtta aagaaattgc 1300

 caaaagttaa caaagagctg gcacttaaat taattgagga agaagaggag 1350

 aagcagaaat ctacatggaa aaagaaagtt aagagtcttc ctaatattct 1400

 caccgatgat cgatttaaag ttatgtttga gaaccctgac ctccaagtag 1450

 atgaagagag tgaagaattt aggcttctga atccacttgt ttcaaaaatt 1500

 agtgaaaaaa ggaagaagaa actaagactc ttagagcaac aagaacttcg 1550

 tgaaaaagaa gaggaggaag agccggaagg aaaaccaagt gatgcagaaa 1600

 gttcggagag ttcagatgat gaaaaagcct gggttgaaga ggtcaggaag 1650

 caacgcagac tcctccagcg ggaggaaaaa gtgaagcggc aggaacgact 1700

 caaggaggac cagcagacag tcctaaagcc ccagttttat gagatcaaag 1750

 caggagaaga atttagaagc ttcaaagatt ctgccacaaa gcagaaactg 1800

 atgaacaaaa cccttgaaga tcgtttgaaa attgaagcaa aaaatgggac 1850

 attgagtgta tccgacacca ccgttggcag caaacaattg acattcacgt 1900

 taaagaggtc tgaacagcag aagaagcaac aggaggctga gaaactacat 1950

 cgacaagaaa ggaaaagact ccgtcgttcg gccggacacc tgaagtcaag 2000

 acacaaaaga ggacggtcgt ttcattgatt tgggaagtgg tcctacctgt 2050

 gattagggag gggtacgtct cccccaaact gatcatcgtt agggtgttaa 2100

 acacagacga ggaaacacac gtttttaaag ttcatgtacg ttcttgtaca 2150

 cagaggtaaa gatttgaaaa cctgtgcctt gtgggttgga ctttgaagct 2200

 ggccccgccg acggccaccg cacagcccca ggggtgtact tgcaagtcgt 2250

 tgctccctgg gaacattgtc ctttccccac ggctttaatc atgaaaacca 2300

 ggttggggtt ttttttttaa tattgtgaaa tgtacaccat gaaatgaaag 2350

 gtttatcctg tgccagaaac caaggtttat catgctctag gaactttttt 2400

 cttacactgc ctaccgccat tcatgattaa accatccaga aataccatcc 2450

 ctgttttacc tggtgtctgt gtattgcctg tgtttgtgtt tataagttta 2500

 tgctgatagg tttgttcggc ttgtttatgt attagtttgg gatttgtttt 2550

 taaataattt ataccaagag agtataatct aatggtgcag gttgagagca 2600

 tcccaaatcc gaaaatctaa aactgtttga gcactgtatt tatctgttct 2650

 tgcactgcta taaagaacta cctgaaactg ggtaatttat aagtaaagaa 2700

 aagaggttta attgactcac agttctacag gtgatacagg aagcatggct 2750

 gtggaggccc tgggaagctt acaatcgtgg cggaaggtga agcggaagca 2800

 ggtatgtcct gcgtggctag agccagagga ggagggcaaa ggggcagatg 2850

 ctgcacactt tcaaacacca gatctccaag aactcactaa cacagaatag 2900

 caagggggaa gtctgccccc atgtttcagt cacctccctc caggcccctc 2950

 ctccaacacc gaagattaca atttgacatg agatttgtgt ggggacacag 3000

 agcaaaacca tatcaagcac tgacatgaca ctggaggaaa atgctcatta 3050

 gagcttttca ggttttggat tttcggattt gggatacttg actagtaaat 3100

 ataatacaga tattccaaaa cacacaaaaa aaccaaagtc taaaagactt 3150

 ctggtcccaa gcatttcaga taagggatac ccaacctgta ataatgggaa 3200

 acaagcagta gaggctgttg gttaatcttg gcacaagttt aattacaggt 3250

 tttttttttt cctgtttctt aagtacagtc aaacataaac ttactggagg 3300

 aaacatttat aaaaataaat atactttcat ttg 3333

<210> 3755
<211> 638
<212> PRT
<213> Homo sapien

<400> 3755
 Met Gln Val Ser Ser Leu Asn Glu Val Lys Ile Tyr Ser Leu Ser
   1               5                  10                  15

 Cys Gly Lys Ser Leu Pro Glu Trp Leu Ser Asp Arg Lys Lys Arg
                  20                  25                  30

 Ala Leu Gln Lys Lys Asp Val Asp Val Arg Arg Arg Ile Glu Leu
                  35                  40                  45

 Ile Gln Asp Phe Glu Met Pro Thr Val Cys Thr Thr Ile Lys Val
                  50                  55                  60

 Ser Lys Asp Gly Gln Tyr Ile Leu Ala Thr Gly Thr Tyr Lys Pro
                  65                  70                  75

 Arg Val Arg Cys Tyr Asp Thr Tyr Gln Leu Ser Leu Lys Phe Glu
                  80                  85                  90

 Arg Cys Leu Asp Ser Glu Val Val Thr Phe Glu Ile Leu Ser Asp
                  95                 100                 105

 Asp Tyr Ser Lys Ile Val Phe Leu His Asn Asp Arg Tyr Ile Glu
                 110                 115                 120

 Phe His Ser Gln Ser Gly Phe Tyr Tyr Lys Thr Arg Ile Pro Lys
                 125                 130                 135

 Phe Gly Arg Asp Phe Ser Tyr His Tyr Pro Ser Cys Asp Leu Tyr
                 140                 145                 150

 Phe Val Gly Ala Ser Ser Glu Val Tyr Arg Leu Asn Leu Glu Gln
                 155                 160                 165

 Gly Arg Tyr Leu Asn Pro Leu Gln Thr Asp Ala Ala Glu Asn Asn
                 170                 175                 180

 Val Cys Asp Ile Asn Ser Val His Gly Leu Phe Ala Thr Gly Thr
                 185                 190                 195

 Ile Glu Gly Arg Val Glu Cys Trp Asp Pro Arg Thr Arg Asn Arg
                 200                 205                 210

 Val Gly Leu Leu Asp Cys Ala Leu Asn Ser Val Thr Ala Asp Ser
                 215                 220                 225

 Glu Ile Asn Ser Leu Pro Thr Ile Ser Ala Leu Lys Phe Asn Gly
                 230                 235                 240

 Ala Leu Thr Met Ala Val Gly Thr Thr Thr Gly Gln Gly Lys Ile
                 245                 250                 255

 Phe Thr Ser Leu Glu Pro Glu His Asp Leu Asn Asp Val Cys Leu
                 260                 265                 270

 Tyr Pro Asn Ser Gly Met Leu Leu Thr Ala Asn Glu Thr Pro Lys
                 275                 280                 285

 Met Gly Ile Tyr Tyr Ile Pro Val Leu Gly Pro Ala Pro Arg Trp
                 290                 295                 300

 Cys Ser Phe Leu Asp Asn Leu Thr Glu Glu Leu Glu Glu Asn Pro
                 305                 310                 315

 Glu Ser Thr Val Tyr Asp Asp Tyr Lys Phe Val Thr Lys Lys Asp
                 320                 325                 330

 Leu Glu Asn Leu Gly Leu Thr His Leu Ile Gly Ser Pro Phe Leu
                 335                 340                 345

 Arg Ala Tyr Met His Gly Phe Phe Met Asp Ile Arg Leu Tyr His
                 350                 355                 360

 Lys Val Lys Leu Met Val Asn Pro Phe Ala Tyr Glu Glu Tyr Arg
                 365                 370                 375

 Lys Asp Lys Ile Arg Gln Lys Ile Glu Glu Thr Arg Ala Gln Arg
                 380                 385                 390

 Val Gln Leu Lys Lys Leu Pro Lys Val Asn Lys Glu Leu Ala Leu
                 395                 400                 405

 Lys Leu Ile Glu Glu Glu Glu Glu Lys Gln Lys Ser Thr Trp Lys
                 410                 415                 420

 Lys Lys Val Lys Ser Leu Pro Asn Ile Leu Thr Asp Asp Arg Phe
                 425                 430                 435

 Lys Val Met Phe Glu Asn Pro Asp Leu Gln Val Asp Glu Glu Ser
                 440                 445                 450

 Glu Glu Phe Arg Leu Leu Asn Pro Leu Val Ser Lys Ile Ser Glu
                 455                 460                 465

 Lys Arg Lys Lys Lys Leu Arg Leu Leu Glu Gln Gln Glu Leu Arg
                 470                 475                 480

 Glu Lys Glu Glu Glu Glu Glu Pro Glu Gly Lys Pro Ser Asp Ala
                 485                 490                 495

 Glu Ser Ser Glu Ser Ser Asp Asp Glu Lys Ala Trp Val Glu Glu
                 500                 505                 510

 Val Arg Lys Gln Arg Arg Leu Leu Gln Arg Glu Glu Lys Val Lys
                 515                 520                 525

 Arg Gln Glu Arg Leu Lys Glu Asp Gln Gln Thr Val Leu Lys Pro
                 530                 535                 540

 Gln Phe Tyr Glu Ile Lys Ala Gly Glu Glu Phe Arg Ser Phe Lys
                 545                 550                 555

 Asp Ser Ala Thr Lys Gln Lys Leu Met Asn Lys Thr Leu Glu Asp
                 560                 565                 570

 Arg Leu Lys Ile Glu Ala Lys Asn Gly Thr Leu Ser Val Ser Asp
                 575                 580                 585

 Thr Thr Val Gly Ser Lys Gln Leu Thr Phe Thr Leu Lys Arg Ser
                 590                 595                 600

 Glu Gln Gln Lys Lys Gln Gln Glu Ala Glu Lys Leu His Arg Gln
                 605                 610                 615

 Glu Arg Lys Arg Leu Arg Arg Ser Ala Gly His Leu Lys Ser Arg
                 620                 625                 630

 His Lys Arg Gly Arg Ser Phe His
                 635

<210> 3756
<211> 6334
<212> DNA
<213> Homo sapien

<400> 3756
 cttaagggcg ggagtctcgg tttgtggtgg cttcgctgag gcagtggtgg 50

 ccgcactata ccgttagaaa ctcaatttcc cggaggttgt gaggcccttt 100

 gaggcgaaat cgctctgggc gtgaaaggag caggcgttgg caatggaagg 150

 accaccgcga cctcaggctg accgtaggga gggatcttga gggccctccg 200

 agtcccctgg gcttgcgctt tctttctttg cagccaccgt gcctaccgcg 250

 aggatgagct cggcctcggt caccgctttc gagaaggagc atctctggat 300

 gtatctgcag gcgctcggct tcgagccagg cccggcaacc attgcctgcg 350

 gaaagatcgt gtcgcacacg cacctcggag tgaacatgtt tgacaagctg 400

 aaccgtgatg cctttcatat aatttcttat tttttgtttc aagttctgga 450

 ccagtctctc accaaagaag ttttcaaatt ttgttggccc ccatttgacc 500

 aaaaaagtga cactgaattc cgaaaacatt gctgtgaatg gataaaaagg 550

 atttctggtg aatgtggaag tagctttcct caagttgttg gttcactatt 600

 tctttctcct ggtggtccta agtttattca tctgatgtat cattttgcaa 650

 gatttgttgc aatgaaatat attaaatcca attctaaaaa ttcttctcat 700

 cattttgtag agacatttaa cataaaacca caggacttgc acaaatgcat 750

 tgccagatgc catttcgcac gtagcagatt tttacaaatt ttgcaaagac 800

 aagattgtgt tacccaaaaa tatcaggaaa atgcacaatt atcagttaag 850

 caggtacgaa acttgagatc tgaatgtata ggattggaaa accaaataaa 900

 gaaaatggaa ccctatgatg accacagtaa tatggaagaa aaaattcaaa 950

 aggttcggtc tttgtgggct tcagtgaatg aaacgctcat gtttttggaa 1000

 aaagagagag aagttgttag ttcggtcctt agtcttgtta accaatatgc 1050

 tttagatgga actaatgttg ctattaatat tccaaggctc ttacttgaca 1100

 aaattgagaa acaaatgttt cagttgcaca taggaaatgt ttatgaggct 1150

 ggaaaactga acctcttaac agttattcag ttattaaatg aagtcttgaa 1200

 ggtgatgaaa tatgaacgtt gtcaggctga tcaagcaaga ttgacggtag 1250

 accttcacta ccttgaaaaa gagaccaaat ttcagaagga aagattatca 1300

 gatctgaaac atatgaggta tagaataaaa gatgatctca caactataag 1350

 acattctgtt gttgaaaagc aaggagaatg gcataaaaag tggaaagaat 1400

 ttcttggttt gtctcctttc agtctaatta aaggttggac tccatctgta 1450

 gatcttttac caccaatgtc tccgctttcg tttgatcctg cctcagaaga 1500

 agtgtatgca aagagtattc tttgtcagta tcctgcttca cttccagatg 1550

 cacataagca acataaccaa gaaaatggtt gcagaggaga cagtgatacc 1600

 ttgggagcgc tacatgatct agccaacagc cctgcctctt tcttgtcgca 1650

 gtcagtttca tcatcagata gaaacagtgt tacagtactt gaaaaggaca 1700

 caaagatggg aactcccaaa gaaaaaaatg aagcaatttc taagaaaata 1750

 ccagaatttg aagtggaaaa ttctccattg tcagatgttg caaagaatac 1800

 agagagtagt gcatttggag ggtctttgcc agctaaaaaa agtgatccat 1850

 ttcaaaaaga gcaagatcat ctggtagaag aggttgccag agcagtttta 1900

 tctgattcac cacagctctc tgaaggaaaa gaaataaaat tagaggaact 1950

 aattgactct ctgggttcta accccttctt aacaaggaat cagattcccc 2000

 gtactccaga aaacttgata actgaaatta ggagctcatg gagaaaagct 2050

 attgaaatgg aagaaaacag aactaaagaa ccaattcaaa tggatgctga 2100

 acatagagaa gtattgccag aatcattacc tgtgttgcac aatcaaagag 2150

 aatttagcat ggctgatttt ctcttagaaa ccactgtatc agattttggc 2200

 cagtctcatt tgactgaaga gaaagttatt tcagattgcg agtgtgtgcc 2250

 tcagaaacat gtgctgacca gtcacataga tgaaccacca acacaaaatc 2300

 agtcagattt gttaaataag aaagtaattt gcaagcaaga tttggaatgt 2350

 ttagccttca ccaagctttc agaaactagc cgaatggaga cattctcccc 2400

 tgctgtcggc aataggatag atgtgatggg tggcagtgaa gaggagttta 2450

 tgaaaatatt ggaccactta gaagtttctt gtaacaaacc ttccacaaat 2500

 aaaactatgt tgtggaattc ttttcagata tcaagtggaa ttagttctaa 2550

 gagttttaaa gataatgatt ttggcatatt acacgaaact ctcccggaag 2600

 aagttggtca tctaagtttt aatagttcca gtagttcaga ggccaatttt 2650

 aaactggagc caaatagtcc tatgcatggt ggcactcttc tagaagatgt 2700

 tgtgggaggg agacagacta ctccagaatc agactttaat ttacaggctc 2750

 ttcgcagtag atacgaggct ctgaagaaat ctctttccaa gaaaagggaa 2800

 gaatcttacc tctcgaattc ccaaacaccc gaaagacaca aaccagaatt 2850

 gagccctact ccccaaaatg tacaaacaga tgatacgctt aactttttgg 2900

 acacctgtga tttgcatact gagcatataa agccatcttt acgcacgtcc 2950

 atcggtgaaa gaaaacggtc tctttcacca ctaattaagt tttctccagt 3000

 ggaacaaaga ttgagaacca caatagcatg tagtcttgga gaactaccta 3050

 atttaaagga agaagacatt ttgaataaga gccttgatgc aaaagaacca 3100

 ccgtctgact tgacaagatg aagacgtacc catttaatat aactatgatg 3150

 cacttaaatt gaagctatgc cacaggatag aaaatgaatt acaacttaaa 3200

 tacatgttgg aagtgtaaca ctgtttttca aggtttaaaa aaattcctaa 3250

 tgccttttag ccttctttaa tatttttagg taaggaaagt atgtttggat 3300

 tttttcctct ttgtaggtat atgagattga aatgtgaagt atttggacaa 3350

 caaacgtcaa gcaatgggaa gccattttga tttcttgagt aatcttgtaa 3400

 gcattaagtg aatgacaaag tagtagtgta acttatttct tatgttataa 3450

 cttcagtcaa ttaatataag gatagttttt gttgtatgtt cactaaatgg 3500

 ttaatataat agccattgaa tatactaatc tttcatctta gagaactata 3550

 caacttttat tgtttcttaa tggaacattc tggctaacca gaaaaagtga 3600

 gaaaagtagt accttgggat gtgtagtcaa gatgacaaat tttaagactg 3650

 gaaaagctct aaacaggctt aatgattctt caggtagaat gatcctgaga 3700

 agtgatgttt gatggaataa agtgcatgtg atgattaagt gaagactggg 3750

 gcagaatgat ttaaaaaaag gaaaaagatg gaagatgagt agacacttgc 3800

 aaggaacact gtcaaactat aaatccattc agtgggttgt ataacattta 3850

 tatttagtct aatttagact ttgataattt aatgctactt ttatatttta 3900

 acaaaaatat aaattaaaat tttcattagt ctgttttgtt gttgggtttt 3950

 tttgtgaggt actccctgtt gggggaaagg aacaaggaac aaccatcaga 4000

 atcccccagt ccctacagaa tagcctcaca gtaacttgag aaaactgaac 4050

 ttggggttaa ataacttgtc acacttgcag tctcctgcct cactccttca 4100

 ggtgccctgc ctagaaaaag acttgtgtct agcatccaag tgaacacata 4150

 ctattgccct ctgtgaacca ggaggaatgg aacaggcaat ggaagggtga 4200

 tagtacctac aatacccttt gtagacccca tctcactacc atcaaaatct 4250

 tgtccactag cccccaaaaa actggcaagg aaagaaggtg gaggggaaat 4300

 ttatggaagt agatggctta atagttattt cttttatctt gggctgcctt 4350

 tctctaagtt ggttgtcctg tcccagtgtg aagacccatc tttttgtgag 4400

 aaaagacaaa agaaagcaca tgtaactacc ttctttgcaa tggaaaagga 4450

 gaaagaaaaa atcttctcct aagttgctgt tttcttttat tagttaataa 4500

 aacaaatcag ggactatgca ggtctatggg gaaaccttta gtctgcttta 4550

 agaaaactca gtatctgaaa atcttaactt agcatgtgat actgtcttat 4600

 cagcatctgc agaagtgcca aagccactgc tagacactta atgtgtatta 4650

 tttcatttaa ttatatttta aatgtgcttc cttggtaatt cttaagctcg 4700

 agaaagagtt tgagaactgc tgctaggaaa tagagattca catttaaccc 4750

 tgtggtactt ttaagaagca ggtacgttgt tgcatatata cttgggtaga 4800

 gattggtaac tatctgatag ggaagctcaa gttggccacc caagtctgag 4850

 aaacccttaa ttactgagaa tcaaaagagc agaatgtctg tagacatttt 4900

 ggatttgtaa aaatcacatt gttgagttat acctgtgatg ggctgaaagt 4950

 ttttggcatt ctttcctgtt cttcatatgc cagtaccata aacaaaaagt 5000

 atctcagatc tgtcactttc ttctcctaaa ccaatgtgat tgcagctttt 5050

 tgccttcagc cttttcccta tccagtatct cctacatagt taccttttga 5100

 tcttaaggaa ctgttttgat tgggtcactt ccttgcctaa aattccattg 5150

 attgttcatt gttaattcta aaatagagtt caaatttaaa ggcatgtaag 5200

 ttcccctgta acggatttcc tctactcccc cttccgctgt aatctcccat 5250

 ttttttactg aaatgcttca gtgagcatgg gtctttagag gtcttgatat 5300

 acaattttcc tgaagcagga ataccttgct ttcctctact agtttaccac 5350

 aattacagct ctcttttaag cctcagaaaa aaatctcact tccgtcttga 5400

 agtcttaatc cacgcttttt atatccatgt gcctactcct tctctgaaat 5450

 ctcctatggt ttatcttttt attcatttaa tatcccacga attgatttta 5500

 ttatatattt tttatggttg catgtggtct ttctagttat agcaatatac 5550

 acatacatgc ataaatacat atacacctat gtaaatgtgt gttgggagta 5600

 tgtattcaca cacatacata taccccaagg ccatgtgtca tctttatcaa 5650

 tatttaagtt ttggaattgt tttgtttgcc tcctatatca tggaataaat 5700

 ggtaaagagg gctaatttat tactctaagt ggatttctta ttacattaat 5750

 atcagacata tagaatgtac tttgttttac tatttgtaag atacaaaggt 5800

 atataaactg acatacatca gcttgaaacc tgagataatg ctaaaatgtt 5850

 ctaattattt taaatgttta aagaggacaa ccatgtaatg ttgctaaaca 5900

 tgaaaaatgt catcaagtgg aataaagaat agctgaagtt aacatttggg 5950

 ggaaattgag ctgaaaacaa aaatatgagt attttgatac cttttcttta 6000

 ccatgagact cttgactatg aagtcaaatt tatctaaagg aaaaacagga 6050

 attctggaga cctgtgtaaa agcagactat tatcttccta ctgtgagagt 6100

 actaaaatta aaatacgttt aatgacgttt tcctcaatgt aaaagcattg 6150

 aagtaaatgt ttcttttatg ttgcagatac atagttgctc tagagatcac 6200

 ctttttcttt atgcattgtg aatagcagtc tgcatcctaa gtttaaaata 6250

 tttgagaatc ctctatggga ctctctgtaa atgttttaaa tactgttgtt 6300

 ttcaataaat attttatact aaaaaaaaaa aaaa 6334

<210> 3757
<211> 955
<212> PRT
<213> Homo sapien

<400> 3757
 Met Ser Ser Ala Ser Val Thr Ala Phe Glu Lys Glu His Leu Trp
   1               5                  10                  15

 Met Tyr Leu Gln Ala Leu Gly Phe Glu Pro Gly Pro Ala Thr Ile
                  20                  25                  30

 Ala Cys Gly Lys Ile Val Ser His Thr His Leu Gly Val Asn Met
                  35                  40                  45

 Phe Asp Lys Leu Asn Arg Asp Ala Phe His Ile Ile Ser Tyr Phe
                  50                  55                  60

 Leu Phe Gln Val Leu Asp Gln Ser Leu Thr Lys Glu Val Phe Lys
                  65                  70                  75

 Phe Cys Trp Pro Pro Phe Asp Gln Lys Ser Asp Thr Glu Phe Arg
                  80                  85                  90

 Lys His Cys Cys Glu Trp Ile Lys Arg Ile Ser Gly Glu Cys Gly
                  95                 100                 105

 Ser Ser Phe Pro Gln Val Val Gly Ser Leu Phe Leu Ser Pro Gly
                 110                 115                 120

 Gly Pro Lys Phe Ile His Leu Met Tyr His Phe Ala Arg Phe Val
                 125                 130                 135

 Ala Met Lys Tyr Ile Lys Ser Asn Ser Lys Asn Ser Ser His His
                 140                 145                 150

 Phe Val Glu Thr Phe Asn Ile Lys Pro Gln Asp Leu His Lys Cys
                 155                 160                 165

 Ile Ala Arg Cys His Phe Ala Arg Ser Arg Phe Leu Gln Ile Leu
                 170                 175                 180

 Gln Arg Gln Asp Cys Val Thr Gln Lys Tyr Gln Glu Asn Ala Gln
                 185                 190                 195

 Leu Ser Val Lys Gln Val Arg Asn Leu Arg Ser Glu Cys Ile Gly
                 200                 205                 210

 Leu Glu Asn Gln Ile Lys Lys Met Glu Pro Tyr Asp Asp His Ser
                 215                 220                 225

 Asn Met Glu Glu Lys Ile Gln Lys Val Arg Ser Leu Trp Ala Ser
                 230                 235                 240

 Val Asn Glu Thr Leu Met Phe Leu Glu Lys Glu Arg Glu Val Val
                 245                 250                 255

 Ser Ser Val Leu Ser Leu Val Asn Gln Tyr Ala Leu Asp Gly Thr
                 260                 265                 270

 Asn Val Ala Ile Asn Ile Pro Arg Leu Leu Leu Asp Lys Ile Glu
                 275                 280                 285

 Lys Gln Met Phe Gln Leu His Ile Gly Asn Val Tyr Glu Ala Gly
                 290                 295                 300

 Lys Leu Asn Leu Leu Thr Val Ile Gln Leu Leu Asn Glu Val Leu
                 305                 310                 315

 Lys Val Met Lys Tyr Glu Arg Cys Gln Ala Asp Gln Ala Arg Leu
                 320                 325                 330

 Thr Val Asp Leu His Tyr Leu Glu Lys Glu Thr Lys Phe Gln Lys
                 335                 340                 345

 Glu Arg Leu Ser Asp Leu Lys His Met Arg Tyr Arg Ile Lys Asp
                 350                 355                 360

 Asp Leu Thr Thr Ile Arg His Ser Val Val Glu Lys Gln Gly Glu
                 365                 370                 375

 Trp His Lys Lys Trp Lys Glu Phe Leu Gly Leu Ser Pro Phe Ser
                 380                 385                 390

 Leu Ile Lys Gly Trp Thr Pro Ser Val Asp Leu Leu Pro Pro Met
                 395                 400                 405

 Ser Pro Leu Ser Phe Asp Pro Ala Ser Glu Glu Val Tyr Ala Lys
                 410                 415                 420

 Ser Ile Leu Cys Gln Tyr Pro Ala Ser Leu Pro Asp Ala His Lys
                 425                 430                 435

 Gln His Asn Gln Glu Asn Gly Cys Arg Gly Asp Ser Asp Thr Leu
                 440                 445                 450

 Gly Ala Leu His Asp Leu Ala Asn Ser Pro Ala Ser Phe Leu Ser
                 455                 460                 465

 Gln Ser Val Ser Ser Ser Asp Arg Asn Ser Val Thr Val Leu Glu
                 470                 475                 480

 Lys Asp Thr Lys Met Gly Thr Pro Lys Glu Lys Asn Glu Ala Ile
                 485                 490                 495

 Ser Lys Lys Ile Pro Glu Phe Glu Val Glu Asn Ser Pro Leu Ser
                 500                 505                 510

 Asp Val Ala Lys Asn Thr Glu Ser Ser Ala Phe Gly Gly Ser Leu
                 515                 520                 525

 Pro Ala Lys Lys Ser Asp Pro Phe Gln Lys Glu Gln Asp His Leu
                 530                 535                 540

 Val Glu Glu Val Ala Arg Ala Val Leu Ser Asp Ser Pro Gln Leu
                 545                 550                 555

 Ser Glu Gly Lys Glu Ile Lys Leu Glu Glu Leu Ile Asp Ser Leu
                 560                 565                 570

 Gly Ser Asn Pro Phe Leu Thr Arg Asn Gln Ile Pro Arg Thr Pro
                 575                 580                 585

 Glu Asn Leu Ile Thr Glu Ile Arg Ser Ser Trp Arg Lys Ala Ile
                 590                 595                 600

 Glu Met Glu Glu Asn Arg Thr Lys Glu Pro Ile Gln Met Asp Ala
                 605                 610                 615

 Glu His Arg Glu Val Leu Pro Glu Ser Leu Pro Val Leu His Asn
                 620                 625                 630

 Gln Arg Glu Phe Ser Met Ala Asp Phe Leu Leu Glu Thr Thr Val
                 635                 640                 645

 Ser Asp Phe Gly Gln Ser His Leu Thr Glu Glu Lys Val Ile Ser
                 650                 655                 660

 Asp Cys Glu Cys Val Pro Gln Lys His Val Leu Thr Ser His Ile
                 665                 670                 675

 Asp Glu Pro Pro Thr Gln Asn Gln Ser Asp Leu Leu Asn Lys Lys
                 680                 685                 690

 Val Ile Cys Lys Gln Asp Leu Glu Cys Leu Ala Phe Thr Lys Leu
                 695                 700                 705

 Ser Glu Thr Ser Arg Met Glu Thr Phe Ser Pro Ala Val Gly Asn
                 710                 715                 720

 Arg Ile Asp Val Met Gly Gly Ser Glu Glu Glu Phe Met Lys Ile
                 725                 730                 735

 Leu Asp His Leu Glu Val Ser Cys Asn Lys Pro Ser Thr Asn Lys
                 740                 745                 750

 Thr Met Leu Trp Asn Ser Phe Gln Ile Ser Ser Gly Ile Ser Ser
                 755                 760                 765

 Lys Ser Phe Lys Asp Asn Asp Phe Gly Ile Leu His Glu Thr Leu
                 770                 775                 780

 Pro Glu Glu Val Gly His Leu Ser Phe Asn Ser Ser Ser Ser Ser
                 785                 790                 795

 Glu Ala Asn Phe Lys Leu Glu Pro Asn Ser Pro Met His Gly Gly
                 800                 805                 810

 Thr Leu Leu Glu Asp Val Val Gly Gly Arg Gln Thr Thr Pro Glu
                 815                 820                 825

 Ser Asp Phe Asn Leu Gln Ala Leu Arg Ser Arg Tyr Glu Ala Leu
                 830                 835                 840

 Lys Lys Ser Leu Ser Lys Lys Arg Glu Glu Ser Tyr Leu Ser Asn
                 845                 850                 855

 Ser Gln Thr Pro Glu Arg His Lys Pro Glu Leu Ser Pro Thr Pro
                 860                 865                 870

 Gln Asn Val Gln Thr Asp Asp Thr Leu Asn Phe Leu Asp Thr Cys
                 875                 880                 885

 Asp Leu His Thr Glu His Ile Lys Pro Ser Leu Arg Thr Ser Ile
                 890                 895                 900

 Gly Glu Arg Lys Arg Ser Leu Ser Pro Leu Ile Lys Phe Ser Pro
                 905                 910                 915

 Val Glu Gln Arg Leu Arg Thr Thr Ile Ala Cys Ser Leu Gly Glu
                 920                 925                 930

 Leu Pro Asn Leu Lys Glu Glu Asp Ile Leu Asn Lys Ser Leu Asp
                 935                 940                 945

 Ala Lys Glu Pro Pro Ser Asp Leu Thr Arg
                 950                 955

<210> 3758
<211> 5498
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3395-3416, 4332-4374, 5476, 5479-5481, 5483-5484, 5486
<223> Unknown base

<400> 3758
 ctcgagccga attcggctcg agcgcctggg cggcggcggc ggcggcgtga 50

 tggctccggc cgcggaccga gagggctact ggggccccac gacctccacg 100

 ctggactggt gcgaggagaa ctactccgtg acctggtaca tcgccgagtt 150

 ctggaataca gtgagtaacc tgatcatgat tatacctcca atgttcggtg 200

 caattcagag tgttagagac ggtctggaaa aacggtacat tgcttcttat 250

 ttagcactca cagtggtagg aatgggatcc tggtgcttcc acatgactct 300

 gaaatatgaa atgcagctat tggatgaact cccaatgata tacagctgtt 350

 gcatatttgt gtactgcatg tttgaatgtt tcaagatcaa gaactcagta 400

 aactaccatc tgctttttac cttagttcta ttcagtttaa tagtaaccac 450

 agtttacctt aaggtaaaag agccaatatt ccatcaggtc atgtatggaa 500

 tgttggtctt tacattagta cttcgatcta tttatattgt tacatgggtt 550

 tatccatggc ttagaggact gggttataca tcattgggta tatttttatt 600

 gggattttta ttttggaata tagataacat attttgtgag tcactgagga 650

 actttcgaaa gaaggtacca cctatcatag gtattaccac acaatttcat 700

 gcatggtggc atattttaac tggccttggt tcctatcttc acatcctttt 750

 cagtttgtat acaagaacac tttacctgag atataggcca aaagtgaagt 800

 ttctctttgg aatctggcca gtgatcctgt ttgagcctct caggaagcat 850

 tgatgaatca ttccaccaag aaaacaaaca agcacctacc atagacctgg 900

 cagaataaat aaggaaatcc ttaaagatct acaagttcaa atatgtcatg 950

 accatcacag cagaggagtg actttctgac taatgctgcc acccacacag 1000

 agaataagga gtagggcctg ctgggtgttt agctcatggc tttatcttat 1050

 ttgtccccct cctcctttca cgctccagtt tataaagaaa cagagatgat 1100

 gtgtgtgtat gcctcaaatg cagaaacagt tgggcttttc ttaacaggtt 1150

 aacagtttgt gctggttata agaaattaac cttcttttct ttttgccaag 1200

 ggttgcatgt gaattatacc tttcttaata tttgattaaa taatgcagtc 1250

 agctaagagc caacaaaacc ccatatccag atagttagct gtgagccagc 1300

 actcagctgt gtcagatttg attaatattg tattaatctc atggatggtt 1350

 ctcaaaggta aaaaaagaga gagaaagaga gagagctagc tgtgggattc 1400

 tgtgtagttc ttcactatct gttccagggc tagtcggagg atcataagca 1450

 agctcagacc tgcccccagt tcagtacttg accacatccc aggatttatg 1500

 gtgtctgtct atggccacag ccaaccagaa tgagtgggtc atcttataac 1550

 ctttctgaag ctccatgagg acatgtatag aatgctgcac cttcagccag 1600

 ctctgctctg atctttgcag atctttaagt tgtcactgtt tctacggcta 1650

 gacaaatatg actggtggtc tagactaccc atagttcatc ctcctcacat 1700

 aacttatttg aagttgtcag ggaatgtcat tacactctga tttttaaaat 1750

 tatgcagtat tttccagttc tcagagaggt catggttgta cccagggaag 1800

 tgtgttgcat taactaaagc taaaattatc agaatcctat ttacataaag 1850

 catattaaaa tatctgctcc ttaattttct gaaggaaata gatgtaagtt 1900

 tctgctactt gaaacctaca gaaccgacaa aaattagggt gctaaaaaaa 1950

 tgacagtgaa atctcatcgt aaggcagcta gttctaattt gcatttgaat 2000

 gtataacaaa ttgcatcact tttcacaaac ttaacacctg cctggagtaa 2050

 aaatctgatt tgacccctct gctcatgttt catcatattt gtagctctgc 2100

 atcatttagc atttttatga ctttttttgc tttatataaa ttattgtaaa 2150

 atccagattg tttttaccac atgatgacgt gactcaggat taaatcctga 2200

 gctacagttt caaaaggaaa atcatttttt tcttatgcaa agatggtaaa 2250

 acactgttgt cattttttcc agtattcaat aagtagcctt tgtacaaatt 2300

 taaaaccaaa aactattctg ttgtttttct tcacctacta gccttagttt 2350

 ttaaccaagt atccaaggat gtcaacttga catccttccc ttagcatgcc 2400

 aacaagccat tagactgatt cttccaccta tttttatgaa cctccaggaa 2450

 gaaaaacact tgccaaaaca ttaagagaac tttgattctg ccttaagagg 2500

 gtataaaact aaaccatttg aaggcacagc ccataagact atacttgatt 2550

 ttgccccaag attctgactt ctggctacat ttcacctgca gttacctggg 2600

 ctatcggccg tgatacattt tttaattcat ttgttttcca ccattatatt 2650

 tttatacttt tcagttagat atacttctgc ataaagagta tatatacagt 2700

 gtaggataaa ggcatatcgt acatggcaat gctgttaaac atggtaagac 2750

 tgaggttctg caggattaaa gtcagattaa gggtacagaa agcacacctt 2800

 gatactgagg ccatttagag caatttgttt aatgagtggt tcagccatca 2850

 ccaccagtgg ccacctgttc aataaaattg cctagcacca cagtggagag 2900

 tcatctacac cccaaggtga gctgtaagac tggccaattc tttgaagacc 2950

 tttttttctg ttgggagaat ggaaagcaga aagggaagcc aggctcttta 3000

 atgttccaag tcagctgtgc ctcacacaag gctctctttt tagctactaa 3050

 gtaacatact caagactttg tatctgtgca gcattttatg gaaatcactg 3100

 gtgacctata ggatattact aaattatttc aatagcttta tttttttcct 3150

 acttggattc taggtggaca ttacagagtt gaattcctca ctaccccctc 3200

 ccgctgtcat ttgttttatt ggaaaacttc atgttaacta gagtgtacaa 3250

 aaagtctgtt tcctgctgag ccaatagtga tttgtttgca tatcacctaa 3300

 tgtgaaaagt gctcatctgt gaactctata gcaaattata ttttagaaaa 3350

 tactttgtga ggccgggcat ggtggcagag cgagactccg tctcnnnnnn 3400

 nnnnnnnnnn nnnnnnctct ataaggatgt aaaagaagca atttgcttgc 3450

 acatctgaat atccttcttg tgtctccatt ttcactcttg aaaactgaaa 3500

 gcaatttgac ttttattttt gtttttctaa agaacagcta ggtgaaagga 3550

 ggttaagctg attgtcactc tgcctgccca ctacctactc cccaccatgg 3600

 tgtttcatga aacatcccca ccacctgaag tgatcttttt aatccttgtg 3650

 atagtaaatg cattgataat taacaggaaa aacatgtttt taaataatct 3700

 acaaatgaga acccaaatgg tagtgttttg tttgacagaa gtaaatcaaa 3750

 tattatggtt taaatataat gcaaaatttc aggacagtta atttgggctt 3800

 cccttaccct aagagggttt ttcttataat aaggagaaga ggtgtggttc 3850

 aaagaaaatt aagagacaaa accttcaggt acataatgca tgaaaatctt 3900

 taaatgcctg caaaaattaa gttctgttat aataccagcc aattctgaat 3950

 tagccaatgc cctaaaagca tctaacaatt taaggttatc ttatgagtcc 4000

 tatgaaaaca attatttgtt gctaaatttg agttttagct accaacgcca 4050

 tgtttacgtg acaagaaatt gttttggccc tgtggtttat gacgtgctgc 4100

 tggataagca tttatgtaaa actgagtatt tcaaagagaa ccatttacaa 4150

 ttggaatttc cacctgtgtg gctgtttgca gacctacctc tgtcttccat 4200

 tttgcatcct gtcagtgcta taattagttt gatcactttg tcttgttttt 4250

 cagtgtctac aattatagct tattcactat gttctaacta tttaaaaata 4300

 atgggccggg cgcggtggct catgcctgtg gnnnnnnnnn nnnnnnnnnn 4350

 nnnnnnnnnn nnnnnnnnnn nnnntggttt ttacatttta aaaacgttta 4400

 gagaaagaag aatatgcaac agaaactgta tgtagcctgc aaagcctaaa 4450

 atgtttactc tctggcttgg gagtttgtct cccctgctct agactgtcag 4500

 caagtggtac agtggtacag tacagtggta ctgcccaact gcacttctct 4550

 gcaaggtgat tctagtgtgc acttgtcaga atgaaaatat gttattcatt 4600

 taagacatct catgtctttg aatgtaatca catgatttgt atttaatatt 4650

 tacatgacct aattattttt tcacgtcagt ttttctagat tggcaatagc 4700

 ctgttgcaaa gtgcctaaac ctttgagaaa aattactatg agcaaggtcc 4750

 atgatttagt tttcaatata aagggaattc cattctatac tgtaaaatcc 4800

 aaaaatgcta gttgccctca gcttttgagt tgacttccag aaagttgaga 4850

 tcttttgacc attttttctc gtgtcatata aaatgtgcca catggtagtt 4900

 gtcaagctgt ggtagtcatg tacacttttt tctttttttt aactttctaa 4950

 aaggaaaagt tcaaagtcct ttccacagtt agtcttcgct tcttttggat 5000

 ttttcttttt agagctaaat tattcatacc aatgaataag tgagtctgtt 5050

 ctaagatata ggggccatta tctatttttg cttaatggac tcatgtggca 5100

 ttgttcacta tcatgccttt ccatacttgt aatatttctg agtcacttat 5150

 taatgtgacc aacagataaa ctgttcaagc taatacagca tttcctaact 5200

 tcatagttgt cgcagatgtt tgttctagta gcgattattt aataaacata 5250

 cattgtactg aatcttacta gcaactaact attttcaggt aatctcagtc 5300

 tgcttattca ctttttccat ttgatttgct aatgccacaa tcatttttct 5350

 agaaaatagt aggataatgt attttttcct gtctgctata atggagacta 5400

 tatttctgca ttcattacct ctcataggtg aaaatattaa attaaataat 5450

 attgttttga ataagaaaaa aaaaanaann nannanaaaa aaagggcg 5498

<210> 3759
<211> 283
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3395-3416, 4332-4374, 5476, 5479-5481, 5483-5484, 5486
<223> Unknown amino acid

<400> 3759
 Ser Ser Arg Ile Arg Leu Glu Arg Leu Gly Gly Gly Gly Gly Gly
   1               5                  10                  15

 Val Met Ala Pro Ala Ala Asp Arg Glu Gly Tyr Trp Gly Pro Thr
                  20                  25                  30

 Thr Ser Thr Leu Asp Trp Cys Glu Glu Asn Tyr Ser Val Thr Trp
                  35                  40                  45

 Tyr Ile Ala Glu Phe Trp Asn Thr Val Ser Asn Leu Ile Met Ile
                  50                  55                  60

 Ile Pro Pro Met Phe Gly Ala Ile Gln Ser Val Arg Asp Gly Leu
                  65                  70                  75

 Glu Lys Arg Tyr Ile Ala Ser Tyr Leu Ala Leu Thr Val Val Gly
                  80                  85                  90

 Met Gly Ser Trp Cys Phe His Met Thr Leu Lys Tyr Glu Met Gln
                  95                 100                 105

 Leu Leu Asp Glu Leu Pro Met Ile Tyr Ser Cys Cys Ile Phe Val
                 110                 115                 120

 Tyr Cys Met Phe Glu Cys Phe Lys Ile Lys Asn Ser Val Asn Tyr
                 125                 130                 135

 His Leu Leu Phe Thr Leu Val Leu Phe Ser Leu Ile Val Thr Thr
                 140                 145                 150

 Val Tyr Leu Lys Val Lys Glu Pro Ile Phe His Gln Val Met Tyr
                 155                 160                 165

 Gly Met Leu Val Phe Thr Leu Val Leu Arg Ser Ile Tyr Ile Val
                 170                 175                 180

 Thr Trp Val Tyr Pro Trp Leu Arg Gly Leu Gly Tyr Thr Ser Leu
                 185                 190                 195

 Gly Ile Phe Leu Leu Gly Phe Leu Phe Trp Asn Ile Asp Asn Ile
                 200                 205                 210

 Phe Cys Glu Ser Leu Arg Asn Phe Arg Lys Lys Val Pro Pro Ile
                 215                 220                 225

 Ile Gly Ile Thr Thr Gln Phe His Ala Trp Trp His Ile Leu Thr
                 230                 235                 240

 Gly Leu Gly Ser Tyr Leu His Ile Leu Phe Ser Leu Tyr Thr Arg
                 245                 250                 255

 Thr Leu Tyr Leu Arg Tyr Arg Pro Lys Val Lys Phe Leu Phe Gly
                 260                 265                 270

 Ile Trp Pro Val Ile Leu Phe Glu Pro Leu Arg Lys His
                 275                 280

<210> 3760
<211> 2568
<212> DNA
<213> Homo sapien

<400> 3760
 aactacgaag atggcggttg cgcgcttggc agctgtggcg gcctgggtac 50

 cttgtcggag ctggggctgg gcagccgtcc ccttcggtcc ccaccgtggc 100

 ctcagcgtgc tgcttgcacg gatacctcag cgggcgccac ggtggctccc 150

 agcttgtaga caaaagacgt cactctcatt ccttaatcga ccagaccttc 200

 caaacctggc ttataagaag ctaaaaggca aaagtccagg aattatcttc 250

 atccctggct atctttctta tatgaatggt acaaaagcgt tggcgattga 300

 ggagttttgc aaatctctag gtcacgcctg cataaggttt gattactcag 350

 gagttggaag ttcagatggt aactcagagg aaagcacact ggggaaatgg 400

 agaaaagatg ttctttctat aattgatgac ttagctgatg ggccacagat 450

 tcttgttgga tctagcctcg gagggtggct tatgcttcat gctgcaattg 500

 cacgaccaga gaaggtcgtg gctcttattg gtgtagctac agctgcagat 550

 accttagtga caaagtttaa tcagcttcct gttgagctaa aaaaggaagt 600

 agagatgaaa ggtgtgtgga gcatgccatc aaaatactct gaagaaggag 650

 tttataacgt tcagtacagt ttcattaaag aagctgaaca tcactgcttg 700

 ttacatagcc caattcctgt gaactgcccc ataagattgc tccatggcat 750

 gaaggatgac attgtacctt ggcatacatc aatgcaggtt gccgatcgag 800

 tactcagcac agatgtggat gtcatcctcc gaaaacacag tgatcaccga 850

 atgagggaaa aagcagacat tcaacttctt gtttacacta ttgatgactt 900

 aattgataag ctctcaacta tagttaacta gtatcacatg tttagttggt 950

 atgtaaacta atgtatccag aagattggaa gagggataag aaatgaaaga 1000

 tcctgatact ttaggctttt ccctttcctc tattttgtaa atataagatg 1050

 agtattattt aatgatgtat ttgcataagt aatgcaaatt gtgaagaagg 1100

 accagctgct gtttagaaaa ttttctcctt ccttctgtcc ttgatttttt 1150

 ttcattaaag tatttccttt ttttaattca agaaaagttt acctttctta 1200

 tgcttatgtt agctatgcca gctcttaatt gcatcctttt ctaattagga 1250

 ttattaataa agcgtgaata ttttgttttt tattatagac agaaatttgt 1300

 aacattactt ctgatttgaa aatgcaattc acaaaatata gggaaatttt 1350

 tattgaataa atttgaaatg atggagaaat ttcagaagca taataaagtt 1400

 cacaataagg ataatacttt atataatgta taaagtatat ataatataat 1450

 atatatgtta tataaactgc acattatatt caaacttaaa attgagcttt 1500

 ttttttaaag gcccaaaatt gtacagtgat acaaggagct atttctaaaa 1550

 tttggcttat gtataatata tttaaatggg gaatttcatc taaagcaatg 1600

 atgtagtatt tttaatattc tgattggtaa aattaaagag gaaattaatc 1650

 tttatatatt atttcttgca gaaacattca ttattttatt aatattgccc 1700

 taagtacaac taggcaagtg attgccacct aaatcagaag acgttctaaa 1750

 gtcagtaaga aagtgtgaaa tgctagtata aaggttattt tttttctttc 1800

 ctaaataact aaagtgaggt gtagattgag ccttgatatt atttagttaa 1850

 tgttttttat taattaattt tggctggact ttatttagct tgattaggtt 1900

 attatctgtc aaacctttta agttgacaac atgactcata tatatacatg 1950

 tgtataagat gagcatgtgt caaagactta ttcgactcat taatgaggaa 2000

 accagcagat agtaaacctg gttcaaagta caattcaaga aactgagtat 2050

 ttatgggcat tgaagaaaaa atgttgagat aaaattgctg tgcagaaaaa 2100

 agtgttaatg aagccgacct gactacttaa ccttagagac ctgctttaca 2150

 aggttggccc ttgattggca tctgggaact tggagttcag ggggcttcca 2200

 ccattcccag aactgatcaa agtagcttac tatatctaaa ctgtaaaaca 2250

 atatagtttc tcctgaacac ctgctttcct tctgggagtc tggaattttg 2300

 gtatgtgcca ggcagagact acctttgtga ccagctccca gtaaaaaccc 2350

 caggcactca gtctctaaca agcttttctg gttgacagtg tttcacaagt 2400

 gctgttacaa ctggttgctg ggagaattaa gctcatcctc tgtgattcca 2450

 ctggcggagg attcttggaa gcttgcactt agtttcccct gacttcaccc 2500

 catgtgtctt ttttcctttg ctgattttgt tttgtatcct ttcactgtaa 2550

 taaatcatgg ccgtgagc 2568

<210> 3761
<211> 306
<212> PRT
<213> Homo sapien

<400> 3761
 Met Ala Val Ala Arg Leu Ala Ala Val Ala Ala Trp Val Pro Cys
   1               5                  10                  15

 Arg Ser Trp Gly Trp Ala Ala Val Pro Phe Gly Pro His Arg Gly
                  20                  25                  30

 Leu Ser Val Leu Leu Ala Arg Ile Pro Gln Arg Ala Pro Arg Trp
                  35                  40                  45

 Leu Pro Ala Cys Arg Gln Lys Thr Ser Leu Ser Phe Leu Asn Arg
                  50                  55                  60

 Pro Asp Leu Pro Asn Leu Ala Tyr Lys Lys Leu Lys Gly Lys Ser
                  65                  70                  75

 Pro Gly Ile Ile Phe Ile Pro Gly Tyr Leu Ser Tyr Met Asn Gly
                  80                  85                  90

 Thr Lys Ala Leu Ala Ile Glu Glu Phe Cys Lys Ser Leu Gly His
                  95                 100                 105

 Ala Cys Ile Arg Phe Asp Tyr Ser Gly Val Gly Ser Ser Asp Gly
                 110                 115                 120

 Asn Ser Glu Glu Ser Thr Leu Gly Lys Trp Arg Lys Asp Val Leu
                 125                 130                 135

 Ser Ile Ile Asp Asp Leu Ala Asp Gly Pro Gln Ile Leu Val Gly
                 140                 145                 150

 Ser Ser Leu Gly Gly Trp Leu Met Leu His Ala Ala Ile Ala Arg
                 155                 160                 165

 Pro Glu Lys Val Val Ala Leu Ile Gly Val Ala Thr Ala Ala Asp
                 170                 175                 180

 Thr Leu Val Thr Lys Phe Asn Gln Leu Pro Val Glu Leu Lys Lys
                 185                 190                 195

 Glu Val Glu Met Lys Gly Val Trp Ser Met Pro Ser Lys Tyr Ser
                 200                 205                 210

 Glu Glu Gly Val Tyr Asn Val Gln Tyr Ser Phe Ile Lys Glu Ala
                 215                 220                 225

 Glu His His Cys Leu Leu His Ser Pro Ile Pro Val Asn Cys Pro
                 230                 235                 240

 Ile Arg Leu Leu His Gly Met Lys Asp Asp Ile Val Pro Trp His
                 245                 250                 255

 Thr Ser Met Gln Val Ala Asp Arg Val Leu Ser Thr Asp Val Asp
                 260                 265                 270

 Val Ile Leu Arg Lys His Ser Asp His Arg Met Arg Glu Lys Ala
                 275                 280                 285

 Asp Ile Gln Leu Leu Val Tyr Thr Ile Asp Asp Leu Ile Asp Lys
                 290                 295                 300

 Leu Ser Thr Ile Val Asn
                 305

<210> 3762
<211> 1493
<212> DNA
<213> Homo sapien

<400> 3762
 ctacagatac tgccgtgtga gagtacctga ggggctcctg aaagacctac 50

 tgccaggacc agtgaccctg gtgatggaac gctcggagga gctcaacaag 100

 gacctaaacc cttttacgcc tcttgtaggc attcggattc ctgatcatgc 150

 ttttatgcaa gacttggctc agatgtttga gggtccgctt gctctcacta 200

 gtgccaacct cagctcccag gccagttctc tgaatgtcga ggagttccag 250

 gatctctggc ctcagttgtc cttggttatt gatgggggac aaattgggga 300

 tggccagagc cccgagtgtc gccttggctc aactgtggtt gatttgtctg 350

 tgcccggaaa gtttggcatc attcgtccag gctgtgccct ggaaagtact 400

 acagccatcc tccaacagaa gtacggactg ctcccctcac atgcgtccta 450

 cctgtgaaac tctgggaagc aggaaggccc aagacctggt gctggatact 500

 atgtgtctgt ccactgacga ctgtcaaggc ctcatttgca gaggccaccg 550

 gagctagggc actagcctga cttttaaggc agtgtgtctt tctgagcact 600

 gtagaccaag cccttggagc tgctggttta gccttgcacc tggggaaagg 650

 atgtatttat ttgtattttc atatatcagc caaaagctga atggaaaagt 700

 taagaacatt cctaggtggc cttattctaa taagtttctt ctgtctgttt 750

 tgtttttcaa ttgaaaagta attaaataac agatttagaa tctagtgaga 800

 gcctcctctc tggtgggtgg tggcatttaa ggttcaaacc agccagaagt 850

 gctggtgctg tttaaaaagt ctcaggtggc tgcgtgtggt ggctcatgcc 900

 tgtaatccca acattctggg aggcccaggc gggagaactg cttgagccca 950

 ggagttcaga atcagcctgg gcaacatagc aatactccgt ctcataaaaa 1000

 ttaataaata aaaagtctca ggtgaccaaa ggctcctgaa gctagaacca 1050

 ggtttggata aagattgaag agccacaggc cactcttccc tctgagccat 1100

 tgggcctagt ggtgtcatgt attgtaattg ctcgcaggga gagcagtctt 1150

 tttggtgtaa tagtgggatg tctgcttagt tggcaggggt tcagtccaaa 1200

 tggaagaata ttgggaaata aacctccact atcctttata gccagggact 1250

 tttttcttat ttattcataa aataaattat agttaattat acccataaca 1300

 cctttattta aatccagtgt tctccgcagc cttttgtcta tttatatgtg 1350

 taccaagtgt taaacataat tattattggg catttgaact ttgtttttct 1400

 ttaaagaaat gctgctatta aacatatttg taaatggaaa aaaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1493

<210> 3763
<211> 127
<212> PRT
<213> Homo sapien

<400> 3763
 Met Glu Arg Ser Glu Glu Leu Asn Lys Asp Leu Asn Pro Phe Thr
   1               5                  10                  15

 Pro Leu Val Gly Ile Arg Ile Pro Asp His Ala Phe Met Gln Asp
                  20                  25                  30

 Leu Ala Gln Met Phe Glu Gly Pro Leu Ala Leu Thr Ser Ala Asn
                  35                  40                  45

 Leu Ser Ser Gln Ala Ser Ser Leu Asn Val Glu Glu Phe Gln Asp
                  50                  55                  60

 Leu Trp Pro Gln Leu Ser Leu Val Ile Asp Gly Gly Gln Ile Gly
                  65                  70                  75

 Asp Gly Gln Ser Pro Glu Cys Arg Leu Gly Ser Thr Val Val Asp
                  80                  85                  90

 Leu Ser Val Pro Gly Lys Phe Gly Ile Ile Arg Pro Gly Cys Ala
                  95                 100                 105

 Leu Glu Ser Thr Thr Ala Ile Leu Gln Gln Lys Tyr Gly Leu Leu
                 110                 115                 120

 Pro Ser His Ala Ser Tyr Leu
                 125

<210> 3764
<211> 2798
<212> DNA
<213> Homo sapien

<400> 3764
 cccttctcaa gatggcgctg cactcaatgc ggaaagcgcg tgagcgctgg 50

 agcttcatcc gggcacttca taagggatcc gcagctgctc ccgctctcca 100

 gaaagacagc aagaagcgag tattttccgg cattcaacct acaggaatcc 150

 tccacctgag caattacctg ggagccattg agagctgggt gaggttacag 200

 gatgaatatg actctgtatt atacagcatt gttgacctcc actccattac 250

 tgtcccccaa gacccagctg tccttcggca gagcatcctg gacatgactg 300

 ctgttcttct tgcctgtggc ataaacccgg aaaaaagcat ccttttccaa 350

 caatctcagg tgtctgaaca cacacaatta agttggatcc tttcctgcat 400

 ggtcagacta cctcgattac aacatttaca tcagtggaag gcaaagacta 450

 ccaagcagaa gcacgatggc acggtgggcc tgctcacata cccagtactc 500

 caggcagccg acattctgtt gtacaagtcc acacacgttc ctgttgggga 550

 ggatcaagtc cagcacatgg aactagttca ggatctagca caaggtttca 600

 acaagaagta tggggagttc tttccagtgc ccgagtccat tctcacatcc 650

 atgaagaagg taaaatccct acgtgatcct tctgccaaaa tgtcgaaatc 700

 agaccctgac aaactggcca ccgtccgaat aacagacagc ccagaggaga 750

 tagtgcagaa attccgcaag gctgtgacag acttcacctc ggaggtcacc 800

 tatgacccgg ctggccgcgc tggcgtgtcc aacatagtgg cggtgcatgc 850

 cgcggtgacg gggctctccg tggaggaagt ggtgcgccgc agcgcgggca 900

 tgaacactgc tcgctacaag ctggccgtgg cagatgctgt gattgagaag 950

 tttgccccaa ttaagcgtga aattgaaaaa ctgaagctgg acaaggacca 1000

 tttagagaag gttttacaaa ttggatcagc aaaagccaaa gaattagcat 1050

 acactgtgtg ccaggaggtg aagaaattgg tgggttttct ataggaagtt 1100

 tcaacgaatc acagcaaggc ttttgtgcct tgcactccat gcattctgat 1150

 aacggcagct ttcctaaaaa gaaaaagtta tagttttggg acatttaatt 1200

 tggtatagct gattattggc tttatttgat gaatattgct ttgtagcttt 1250

 gaaatacgac agtgttccaa atcccatcaa caaaatgctg tgaacaacaa 1300

 caacaaaaaa taaatcaaga aggcatagct gtctgaatcc cgaattattg 1350

 aggcacactc cttggcctgc agaaatgtga ttgaagtaag gagtaatttg 1400

 ggaaatggag tatcatttgt gcttctctct ggagtactta ctgtaacaga 1450

 tgcacacgtt atctacttca acccttttat aaagcaatat atagaggtct 1500

 tagatgtata atccttgaga tgccatttga tcagatgcca atttgtattc 1550

 agagctcata aaaacaagtc cattcttata gtttgtttgt cactgagacg 1600

 gtgcctgatt taatatattt aagctgctta acttgttttc caagagataa 1650

 caccaactgt tccagcaata atttgttttt taattcagag atatgggata 1700

 tgatcttcta aggaggttgc attattttga cctgatttat ttattgtaca 1750

 agagcccaag tccctgaatt atattcttaa taagtgcttt cttgcattca 1800

 tttcagttta gtctcaccaa cccactatga attaggagaa ttattgtcat 1850

 tttacacatg aggaaagtga ggctgagaga atccaattag cttgtacgat 1900

 atcactccat aagagaagca aatctgagag taaaaccctt accccttatt 1950

 cttaagaata gtgcttgttt attcagtaca aaaaaaatgc tgaaaggcag 2000

 cgttttttag actctaaaca ttctgatttt gaaggtgggt attggaacga 2050

 ctgatgatgt tttttatatc atcaattcag ccaatggatg cgaacttaaa 2100

 atctggattc acagaaccgt ggtcacattt ccccatcaaa atccccaagg 2150

 cgggtcccaa gttctctcct ctacgctcat tgcagaaata ctttgaaata 2200

 ggttctgcca gtctacaata gcagtgaaga ctgacaaatc agatattccc 2250

 aatgactgac agcttctcat cttgcctcta cctcagttaa gtaatgtcac 2300

 cctgaaacct agcttttctg cacttccatt tctgacacct gaaaatgaaa 2350

 atgataatcc taacttatac accaagacct gttagcaaga tcgattttgt 2400

 aacagaaatt gcttataagt tttttatcag taaggaccat gatcaccatt 2450

 tgtacataca taactaggtt gttgagcaaa gcatttttgc tcatgtttct 2500

 taaggaagta gagtagtcct tgtgtcagaa cacatgttaa tccacaaaac 2550

 gccgcatccc agattccaaa ttaaaacatc gtttttagga ttcttggagc 2600

 tagcctggat catgggtaaa ggaaacattt tgccttttgt atcttatact 2650

 ggaatgggat gtctgtaagt cctagaacct ctttgagcat atttcttaca 2700

 agcctctgtt ttttcccctt taaaggaaac tttgaaagga ttgtgaatac 2750

 tggaaaatga caaaactaaa ggtagatcta ccaaaaaaaa aaaaaaaa 2798

<210> 3765
<211> 360
<212> PRT
<213> Homo sapien

<400> 3765
 Met Ala Leu His Ser Met Arg Lys Ala Arg Glu Arg Trp Ser Phe
   1               5                  10                  15

 Ile Arg Ala Leu His Lys Gly Ser Ala Ala Ala Pro Ala Leu Gln
                  20                  25                  30

 Lys Asp Ser Lys Lys Arg Val Phe Ser Gly Ile Gln Pro Thr Gly
                  35                  40                  45

 Ile Leu His Leu Ser Asn Tyr Leu Gly Ala Ile Glu Ser Trp Val
                  50                  55                  60

 Arg Leu Gln Asp Glu Tyr Asp Ser Val Leu Tyr Ser Ile Val Asp
                  65                  70                  75

 Leu His Ser Ile Thr Val Pro Gln Asp Pro Ala Val Leu Arg Gln
                  80                  85                  90

 Ser Ile Leu Asp Met Thr Ala Val Leu Leu Ala Cys Gly Ile Asn
                  95                 100                 105

 Pro Glu Lys Ser Ile Leu Phe Gln Gln Ser Gln Val Ser Glu His
                 110                 115                 120

 Thr Gln Leu Ser Trp Ile Leu Ser Cys Met Val Arg Leu Pro Arg
                 125                 130                 135

 Leu Gln His Leu His Gln Trp Lys Ala Lys Thr Thr Lys Gln Lys
                 140                 145                 150

 His Asp Gly Thr Val Gly Leu Leu Thr Tyr Pro Val Leu Gln Ala
                 155                 160                 165

 Ala Asp Ile Leu Leu Tyr Lys Ser Thr His Val Pro Val Gly Glu
                 170                 175                 180

 Asp Gln Val Gln His Met Glu Leu Val Gln Asp Leu Ala Gln Gly
                 185                 190                 195

 Phe Asn Lys Lys Tyr Gly Glu Phe Phe Pro Val Pro Glu Ser Ile
                 200                 205                 210

 Leu Thr Ser Met Lys Lys Val Lys Ser Leu Arg Asp Pro Ser Ala
                 215                 220                 225

 Lys Met Ser Lys Ser Asp Pro Asp Lys Leu Ala Thr Val Arg Ile
                 230                 235                 240

 Thr Asp Ser Pro Glu Glu Ile Val Gln Lys Phe Arg Lys Ala Val
                 245                 250                 255

 Thr Asp Phe Thr Ser Glu Val Thr Tyr Asp Pro Ala Gly Arg Ala
                 260                 265                 270

 Gly Val Ser Asn Ile Val Ala Val His Ala Ala Val Thr Gly Leu
                 275                 280                 285

 Ser Val Glu Glu Val Val Arg Arg Ser Ala Gly Met Asn Thr Ala
                 290                 295                 300

 Arg Tyr Lys Leu Ala Val Ala Asp Ala Val Ile Glu Lys Phe Ala
                 305                 310                 315

 Pro Ile Lys Arg Glu Ile Glu Lys Leu Lys Leu Asp Lys Asp His
                 320                 325                 330

 Leu Glu Lys Val Leu Gln Ile Gly Ser Ala Lys Ala Lys Glu Leu
                 335                 340                 345

 Ala Tyr Thr Val Cys Gln Glu Val Lys Lys Leu Val Gly Phe Leu
                 350                 355                 360

<210> 3766
<211> 2721
<212> DNA
<213> Homo sapien

<400> 3766
 gccggcgcgg aggagcgggc ggccgcggct gtgccctctc ctactcctca 50

 ccgcgcgagc gcggggaacc agtagccgcg gctgcttcgg ttgccgcggt 100

 cggtggtcgt tatggattct ccatgggacg agttggctct ggccttctcc 150

 cgcacgtcca tgtttccctt ttttgacatc gcgcactatc tagtgtcagt 200

 gatggcggtg aaacgtcagc cgggagcagc tgcattggca tggaagaatc 250

 ctatttcaag ctggtttact gctatgctcc actgttttgg tggaggaatt 300

 ttatcctgtc tactgcttgc agagcctcca ttgaagtttc ttgcaaacca 350

 cactaacata ttactggcat cttcaatctg gtatattaca tttttttgcc 400

 cgcatgacct agtttcccag ggctattcat atctacctgt tcaactactg 450

 gcttcgggaa tgaaggaagt gaccagaact tggaaaatag taggtggagt 500

 cacacatgct aatagctatt acaaaaatgg ctggatagtc atgatagcta 550

 ttggatgggc ccgaggtgca ggtggtacca ttataacgaa ttttgagagg 600

 ttggtaaaag gagattggaa accagaaggt gatgaatggc tgaagatgtc 650

 ataccctgcc aaggtaaccc tgctggggtc agttatcttc acattccagc 700

 acacccagca tctggcaata tcaaagcata atcttatgtt cctttatacc 750

 atctttattg tggccacaaa gataaccatg atgactacac agacttctac 800

 tatgacattt gctccttttg aggatacatt gagttggatg ctatttggct 850

 ggcagcagcc gttttcatca tgtgagaaga aaagtgaagc aaagtcacct 900

 tccaatggcg ttgggtcatt ggcctcaaag ccggtagatg ttgcctcaga 950

 taatgttaaa aagaaacata ctaagaagaa tgaataaatt tacgtgatga 1000

 gctctacaag gccaaaaatt ttttttctta tctacctgtt atattgtgct 1050

 aatttttcta tgtatgtgat gtgaaatgaa gactatatat atggaatgga 1100

 ggtgacagaa agaaagaaat tctttgtttg agggagactt cccctttctg 1150

 gattgtattt gtagagtgtt acgagtgtat catgtgatta tgctttaccg 1200

 gtataagaga ttctgttgtg attatttgaa tagttttata ttaataaaag 1250

 aagacaaaat tttttaaatg ttagaaaaag cagatctgtc attgcaaagt 1300

 aacaaaaatt ttaagctttt aaaaatgtag atttttcata tttttaaaat 1350

 ttgaatctat ttgagcttta gttcagcaga attaaatttt tacttgacat 1400

 tatcattaaa attgctaggt atggagaaca attcctattt tattttgaac 1450

 actgagaaga gtaaactttt cctaaaacac tttatattat aaatgaaaat 1500

 aaattgctag tttatatttt agatataaac atcatatttt ttattaatac 1550

 ctacatcaaa tggaaaatat ctgaaatttt ttttccatag caggtatttt 1600

 ctactagaag tagttttact acttttcatt tagaacagag tatgagtctt 1650

 aatctgaagt ctttttcatg cccttgtttt aaaaaaacta ctttttttgg 1700

 cctcaaaaaa atcaagggtg taatttttaa taaattgtta atcctatgtt 1750

 ttgtaatttt cattttagga gcttgactta tttttttctc tctcataaaa 1800

 acacatttgt tttaattgta ggagaaattt tctcagcatt ttgcatgttc 1850

 tttctaatct ttgttggtct gaatatattg gtagtaatta ctgtaattat 1900

 tcaacaaaaa gcatatccgt tcaaaaattt ttccactatg tcttttttct 1950

 agtggctact gttttagttt tctagttgaa tatctctgac aagctttcgt 2000

 atggttttgt tatattttca tctacatgta atgtgttatt aattttatta 2050

 aatgaaaact aatcaccttc atgtggaaat gctctgagaa ttgtccttag 2100

 gcatttggta gtaaccagct aaccaagaag aaacagagaa accagaactt 2150

 catatggcag tccatttaga tgaagaatga tgatataaaa tctggttcct 2200

 tcttagcaaa ataaaaaaca aacaagaaaa gatactaaat gatgttaatt 2250

 ttcttacttt atgatttaga agtccagtta taatattaaa actctgtgac 2300

 atagtttctt ttaccaaaac catgaaccta ctccccgtat caggtatttt 2350

 cgatggttta gaagtactca agtcacatca cattcaagtt agaagttttt 2400

 tttttgttgt tgttatttta aatttttaac aaatataaac accagcagat 2450

 actattactt gcttaaaaaa ttgggagggg gcacttttca tagtcttgga 2500

 atgctaagaa gttttatttt taatattgtg acagaaagct ttaagtattt 2550

 aagagctctg tattatattt gatactctta cagttaaaaa cttttcaaaa 2600

 ttaatacatt gttaattatt gaccagtttt gaagtttggg tttaactgta 2650

 gttgaaatgg aaggactctt gttttacact tgtattaaag ataaatttat 2700

 taaaataagt tatttagcac c 2721

<210> 3767
<211> 291
<212> PRT
<213> Homo sapien

<400> 3767
 Met Asp Ser Pro Trp Asp Glu Leu Ala Leu Ala Phe Ser Arg Thr
   1               5                  10                  15

 Ser Met Phe Pro Phe Phe Asp Ile Ala His Tyr Leu Val Ser Val
                  20                  25                  30

 Met Ala Val Lys Arg Gln Pro Gly Ala Ala Ala Leu Ala Trp Lys
                  35                  40                  45

 Asn Pro Ile Ser Ser Trp Phe Thr Ala Met Leu His Cys Phe Gly
                  50                  55                  60

 Gly Gly Ile Leu Ser Cys Leu Leu Leu Ala Glu Pro Pro Leu Lys
                  65                  70                  75

 Phe Leu Ala Asn His Thr Asn Ile Leu Leu Ala Ser Ser Ile Trp
                  80                  85                  90

 Tyr Ile Thr Phe Phe Cys Pro His Asp Leu Val Ser Gln Gly Tyr
                  95                 100                 105

 Ser Tyr Leu Pro Val Gln Leu Leu Ala Ser Gly Met Lys Glu Val
                 110                 115                 120

 Thr Arg Thr Trp Lys Ile Val Gly Gly Val Thr His Ala Asn Ser
                 125                 130                 135

 Tyr Tyr Lys Asn Gly Trp Ile Val Met Ile Ala Ile Gly Trp Ala
                 140                 145                 150

 Arg Gly Ala Gly Gly Thr Ile Ile Thr Asn Phe Glu Arg Leu Val
                 155                 160                 165

 Lys Gly Asp Trp Lys Pro Glu Gly Asp Glu Trp Leu Lys Met Ser
                 170                 175                 180

 Tyr Pro Ala Lys Val Thr Leu Leu Gly Ser Val Ile Phe Thr Phe
                 185                 190                 195

 Gln His Thr Gln His Leu Ala Ile Ser Lys His Asn Leu Met Phe
                 200                 205                 210

 Leu Tyr Thr Ile Phe Ile Val Ala Thr Lys Ile Thr Met Met Thr
                 215                 220                 225

 Thr Gln Thr Ser Thr Met Thr Phe Ala Pro Phe Glu Asp Thr Leu
                 230                 235                 240

 Ser Trp Met Leu Phe Gly Trp Gln Gln Pro Phe Ser Ser Cys Glu
                 245                 250                 255

 Lys Lys Ser Glu Ala Lys Ser Pro Ser Asn Gly Val Gly Ser Leu
                 260                 265                 270

 Ala Ser Lys Pro Val Asp Val Ala Ser Asp Asn Val Lys Lys Lys
                 275                 280                 285

 His Thr Lys Lys Asn Glu
                 290

<210> 3768
<211> 4916
<212> DNA
<213> Homo sapien

<400> 3768
 agaattcgga gcgcggaaga gccagagctg cgagcgcctg gagctggatc 50

 tctctccggt cgcgcacgcc gaggccagta gggagagaag atggtggttc 100

 tccgcagcag cttggagctg cacaaccact ccgcggcctc ggccacgggc 150

 tccttggacc tgtccagtga cttcctcagt ctggagcaca tcggccggag 200

 gcggctccgc tcggccggcg cggcgcagaa gaaacccgcg gcgaccacag 250

 ccaaagcggg cgatgggtca tcagttaagg aagttgaaac ctaccaccgg 300

 acacgtgctt taagatcttt gagaaaagat gcacagaatt cttcagattc 350

 tagttttgag aagaatgtgg aaataacgga gcaacttgct aatggcaggc 400

 attttacaag gcagttggcc agacagcagg ctgataaaaa aaaagaagag 450

 cacagagaag acaaagtgat tccagttact cggtcattga gggctagaaa 500

 catcgttcaa agtacagaac acttacatga agataatggt gatgttgaag 550

 tgcgtcgaag ttgtaggatt agaagtcgtt atagtggtgt aaaccagtcc 600

 atgctgtttg acaaacttat aactaacact gctgaagctg tacttcaaaa 650

 aatggatgac atgaagaaga tgcgtagaca gcgaatgaga gaacttgaag 700

 acttgggagt gtttaatgaa acagaagaaa gcaatcttaa tatgtacaca 750

 agaggaaaac agaaagatat tcaaagaact gatgaagaaa caactgataa 800

 tcaagaaggc agtgtggagt catctgaaga gggtgaagac caagaacatg 850

 aagatgatgg tgaagatgaa gatgatgaag atgatgatga tgatgacgat 900

 gatgatgatg atgatgatga tgaagatgat gaagatgaag aagatggaga 950

 agaagagaat cagaagcgat attatcttag acagagaaaa gctactgttt 1000

 actatcaggc tccattggaa aaacctcgtc accagagaaa gcccaacata 1050

 ttttatagtg gcccagcttc tcctgcaaga ccaagatacc gattatcttc 1100

 cgcaggacca agaagtcctt actgtaaacg aatgaacagg cgaaggcatg 1150

 caatccacag tagtgactcg acttcatctt cctcctctga agatgaacag 1200

 cactttgaga ggcggaggaa aaggagtcgt aatagggcta tcaataggtg 1250

 cctcccacta aattttcgga aagatgaatt aaaaggcatt tataaagatc 1300

 gaatgaaaat tggagcaagc cttgccgatg ttgatccaat gcaactagat 1350

 tcttcagtac gatttgatag tgttggtggc ctgtctaatc atatagcagc 1400

 tctaaaagag atggtggtgt ttccattact ttatccagaa gtctttgaaa 1450

 aatttaaaat tcaaccccca agaggttgtt tgttttatgg gccacctgga 1500

 actggaaaga ctctggttgc cagagcactt gccaatgagt gcagtcaagg 1550

 ggataaaaga gtagcatttt tcatgaggaa aggtgctgat tgtctaagta 1600

 aatgggtagg agaatctgaa agacagctac gattgctgtt tgatcaggcc 1650

 tatcagatgc gcccatcaat tatttttttt gacgaaattg atggtctggc 1700

 tccagtacgg tcaagcaggc aagatcagat tcacagttct attgtttcca 1750

 ccctgctagc tcttatggat ggattggaca gcagagggga aattgtggtc 1800

 attggtgcta cgaacaggct agattctata gatcctgctt tacgaaggcc 1850

 tggtcgcttt gatagagaat tcctctttag cctgcctgat aaagaggctc 1900

 gaaaagagat tctaaagatt cacaccaggg attggaatcc caaaccactg 1950

 gacacatttt tagaagagct agcagaaaac tgtgttggat actgtggagc 2000

 agatattaaa tcaatatgtg ctgaagctgc tttatgtgct ttacgacgac 2050

 gctacccaca gatctatacc actagtgaga aactgcagtt ggatctctct 2100

 tcaattaata tctcagctaa ggatttcgag gtagctatgc aaaagatgat 2150

 accagcctcc caaagagctg tgacatcacc tgggcaggca ctgtccaccg 2200

 ttgtgaaacc actcctgcaa aacactgttg acaagatttt agaagccctg 2250

 cagagagtat ttccacatgc agaattcaga acaaataaaa cattagactc 2300

 agatatttct tgtcctctgc tagaaagtga cttggcttac agtgatgatg 2350

 atgttccatc agtttatgaa aatggacttt ctcagaaatc ttctcataag 2400

 gcaaaagaca attttaattt tcttcatttg aatagaaatg cttgttacca 2450

 acctatgtct tttcgaccaa gaatattgat agtaggagaa ccaggatttg 2500

 ggcaaggttc tcacttggca ccagctgtca ttcatgcttt ggaaaagttt 2550

 actgtatata cattagacat tcctgttctt tttggagtta gtactacatc 2600

 ccctgaagaa acatgtgccc aggtgattcg tgaagctaag agaacagcac 2650

 caagtatagt gtatgttcct catatccacg tgtggtggga aatagttgga 2700

 ccgacactta aagccacatt taccacatta ttacagaata ttccttcatt 2750

 tgctccagtt ttactacttg caacttctga caaaccccat tccgctttgc 2800

 cagaagaggt gcaagaattg tttatccgtg attatggaga gatttttaat 2850

 gtccagttac cggataaaga agaacggaca aaattttttg aagatttaat 2900

 tctaaaacaa gctgctaagc ctcctatatc aaaaaagaaa gcagttttgc 2950

 aggctttgga ggtactccca gtagcaccac cacctgagcc aagatcactg 3000

 acagcagaag aagtgaaacg actagaagaa caagaagaag atacatttag 3050

 agaactgagg attttcttaa gaaatgttac acataggctt gctattgaca 3100

 agcgattccg agtgtttact aagcctgttg accctgatga ggttcctgat 3150

 tatgtcactg taataaagca accaatggac ctttcatctg taatcagtaa 3200

 aattgatcta cacaagtatc tgactgtgaa agactatttg agagatattg 3250

 atctaatctg tagtaatgcc ttagaataca atccagatag agatcctgga 3300

 gatcgtctta ttaggcatag agcctgtgct ttaagagata ctgcctatgc 3350

 cataattaaa gaagaacttg atgaagactt tgagcagctc tgtgaagaaa 3400

 ttcaggaatc tagaaagaaa agaggttgta gctcctccaa atatgccccg 3450

 tcttactacc atgtgatgcc aaagcaaaat tccactcttg ttggtgataa 3500

 aagatcagac ccagagcaga atgaaaagct aaagacaccg agtactcctg 3550

 tggcttgcag cactcctgct cagttgaaga ggaaaattcg caaaaagtca 3600

 aactggtact taggcaccat aaaaaagcga aggaagattt cacaggcaaa 3650

 ggatgatagc cagaatgcca tagatcacaa aattgagagt gatacagagg 3700

 aaactcaaga cacaagtgta gatcataatg agaccggaaa cacaggagag 3750

 tcttcggtgg aagaaaatga aaaacagcaa aatgcctctg aaagcaaact 3800

 ggaattgaga aataattcaa atacttgtaa tatagagaat gagcttgaag 3850

 actctaggaa gactacagca tgtacagaat tgagagacaa gattgcttgt 3900

 aatggagatg cttctagctc tcagataata catatttctg atgaaaatga 3950

 aggaaaagaa atgtgtgttc tgcgaatgac tcgagctaga cgttcccagg 4000

 tagaacagca gcagctcatc actgttgaaa aggctttggc aattctttct 4050

 cagcctacac cctcacttgt tgtggatcat gagcgattaa aaaatctttt 4100

 gaagactgtt gttaaaaaaa gtcaaaacta caacatattt cagttggaaa 4150

 atttgtatgc agtaatcagc caatgtattt atcggcatcg caaggaccat 4200

 gataaaacat cacttattca gaaaatggag caagaggtag aaaacttcag 4250

 ttgttccaga tgatgatgtc atggtatcga gtattcttta tattcagttc 4300

 ctatttaagt catttttgtc atgtccgcct aattgatgta gtatgaaacc 4350

 ctgcatcttt aaggaaaaga ttaaaatagt aaaataaaag tatttaaact 4400

 ttcctgatat ttatgtacat attaagataa atgtcatgtg taagataact 4450

 gataaatatt ggaactttgc tagaacaaga ccctgtagta atagtaataa 4500

 tagttgaagt ttggccaact cttaataaag ttattttggt aactaatgtt 4550

 ttatggcact taagaataat tagcagcgtt aaattttgtt tgtattaagc 4600

 acttttaatt ttatccttcc taaaaatagt ttattgtatc tgacaagaaa 4650

 cttacttaac cattgtgtcc ttcccatctt ttttgtcatc tttgttttct 4700

 tcaaatgccc tcctcccatc tgccttgaga ttcccttgtc ttcacttaaa 4750

 agccagagtg caagtcatga tttgcgggag ggctcttgaa ccacttctgg 4800

 ctgcaccaca attctgtact tgagtatcac agtcattgtt tttgagacaa 4850

 acatttttat aattctaatt tgggttaata aagattttaa atatttaaaa 4900

 aaaaaaaaaa aaaaaa 4916

<210> 3769
<211> 1390
<212> PRT
<213> Homo sapien

<400> 3769
 Met Val Val Leu Arg Ser Ser Leu Glu Leu His Asn His Ser Ala
   1               5                  10                  15

 Ala Ser Ala Thr Gly Ser Leu Asp Leu Ser Ser Asp Phe Leu Ser
                  20                  25                  30

 Leu Glu His Ile Gly Arg Arg Arg Leu Arg Ser Ala Gly Ala Ala
                  35                  40                  45

 Gln Lys Lys Pro Ala Ala Thr Thr Ala Lys Ala Gly Asp Gly Ser
                  50                  55                  60

 Ser Val Lys Glu Val Glu Thr Tyr His Arg Thr Arg Ala Leu Arg
                  65                  70                  75

 Ser Leu Arg Lys Asp Ala Gln Asn Ser Ser Asp Ser Ser Phe Glu
                  80                  85                  90

 Lys Asn Val Glu Ile Thr Glu Gln Leu Ala Asn Gly Arg His Phe
                  95                 100                 105

 Thr Arg Gln Leu Ala Arg Gln Gln Ala Asp Lys Lys Lys Glu Glu
                 110                 115                 120

 His Arg Glu Asp Lys Val Ile Pro Val Thr Arg Ser Leu Arg Ala
                 125                 130                 135

 Arg Asn Ile Val Gln Ser Thr Glu His Leu His Glu Asp Asn Gly
                 140                 145                 150

 Asp Val Glu Val Arg Arg Ser Cys Arg Ile Arg Ser Arg Tyr Ser
                 155                 160                 165

 Gly Val Asn Gln Ser Met Leu Phe Asp Lys Leu Ile Thr Asn Thr
                 170                 175                 180

 Ala Glu Ala Val Leu Gln Lys Met Asp Asp Met Lys Lys Met Arg
                 185                 190                 195

 Arg Gln Arg Met Arg Glu Leu Glu Asp Leu Gly Val Phe Asn Glu
                 200                 205                 210

 Thr Glu Glu Ser Asn Leu Asn Met Tyr Thr Arg Gly Lys Gln Lys
                 215                 220                 225

 Asp Ile Gln Arg Thr Asp Glu Glu Thr Thr Asp Asn Gln Glu Gly
                 230                 235                 240

 Ser Val Glu Ser Ser Glu Glu Gly Glu Asp Gln Glu His Glu Asp
                 245                 250                 255

 Asp Gly Glu Asp Glu Asp Asp Glu Asp Asp Asp Asp Asp Asp Asp
                 260                 265                 270

 Asp Asp Asp Asp Asp Asp Asp Glu Asp Asp Glu Asp Glu Glu Asp
                 275                 280                 285

 Gly Glu Glu Glu Asn Gln Lys Arg Tyr Tyr Leu Arg Gln Arg Lys
                 290                 295                 300

 Ala Thr Val Tyr Tyr Gln Ala Pro Leu Glu Lys Pro Arg His Gln
                 305                 310                 315

 Arg Lys Pro Asn Ile Phe Tyr Ser Gly Pro Ala Ser Pro Ala Arg
                 320                 325                 330

 Pro Arg Tyr Arg Leu Ser Ser Ala Gly Pro Arg Ser Pro Tyr Cys
                 335                 340                 345

 Lys Arg Met Asn Arg Arg Arg His Ala Ile His Ser Ser Asp Ser
                 350                 355                 360

 Thr Ser Ser Ser Ser Ser Glu Asp Glu Gln His Phe Glu Arg Arg
                 365                 370                 375

 Arg Lys Arg Ser Arg Asn Arg Ala Ile Asn Arg Cys Leu Pro Leu
                 380                 385                 390

 Asn Phe Arg Lys Asp Glu Leu Lys Gly Ile Tyr Lys Asp Arg Met
                 395                 400                 405

 Lys Ile Gly Ala Ser Leu Ala Asp Val Asp Pro Met Gln Leu Asp
                 410                 415                 420

 Ser Ser Val Arg Phe Asp Ser Val Gly Gly Leu Ser Asn His Ile
                 425                 430                 435

 Ala Ala Leu Lys Glu Met Val Val Phe Pro Leu Leu Tyr Pro Glu
                 440                 445                 450

 Val Phe Glu Lys Phe Lys Ile Gln Pro Pro Arg Gly Cys Leu Phe
                 455                 460                 465

 Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu Val Ala Arg Ala Leu
                 470                 475                 480

 Ala Asn Glu Cys Ser Gln Gly Asp Lys Arg Val Ala Phe Phe Met
                 485                 490                 495

 Arg Lys Gly Ala Asp Cys Leu Ser Lys Trp Val Gly Glu Ser Glu
                 500                 505                 510

 Arg Gln Leu Arg Leu Leu Phe Asp Gln Ala Tyr Gln Met Arg Pro
                 515                 520                 525

 Ser Ile Ile Phe Phe Asp Glu Ile Asp Gly Leu Ala Pro Val Arg
                 530                 535                 540

 Ser Ser Arg Gln Asp Gln Ile His Ser Ser Ile Val Ser Thr Leu
                 545                 550                 555

 Leu Ala Leu Met Asp Gly Leu Asp Ser Arg Gly Glu Ile Val Val
                 560                 565                 570

 Ile Gly Ala Thr Asn Arg Leu Asp Ser Ile Asp Pro Ala Leu Arg
                 575                 580                 585

 Arg Pro Gly Arg Phe Asp Arg Glu Phe Leu Phe Ser Leu Pro Asp
                 590                 595                 600

 Lys Glu Ala Arg Lys Glu Ile Leu Lys Ile His Thr Arg Asp Trp
                 605                 610                 615

 Asn Pro Lys Pro Leu Asp Thr Phe Leu Glu Glu Leu Ala Glu Asn
                 620                 625                 630

 Cys Val Gly Tyr Cys Gly Ala Asp Ile Lys Ser Ile Cys Ala Glu
                 635                 640                 645

 Ala Ala Leu Cys Ala Leu Arg Arg Arg Tyr Pro Gln Ile Tyr Thr
                 650                 655                 660

 Thr Ser Glu Lys Leu Gln Leu Asp Leu Ser Ser Ile Asn Ile Ser
                 665                 670                 675

 Ala Lys Asp Phe Glu Val Ala Met Gln Lys Met Ile Pro Ala Ser
                 680                 685                 690

 Gln Arg Ala Val Thr Ser Pro Gly Gln Ala Leu Ser Thr Val Val
                 695                 700                 705

 Lys Pro Leu Leu Gln Asn Thr Val Asp Lys Ile Leu Glu Ala Leu
                 710                 715                 720

 Gln Arg Val Phe Pro His Ala Glu Phe Arg Thr Asn Lys Thr Leu
                 725                 730                 735

 Asp Ser Asp Ile Ser Cys Pro Leu Leu Glu Ser Asp Leu Ala Tyr
                 740                 745                 750

 Ser Asp Asp Asp Val Pro Ser Val Tyr Glu Asn Gly Leu Ser Gln
                 755                 760                 765

 Lys Ser Ser His Lys Ala Lys Asp Asn Phe Asn Phe Leu His Leu
                 770                 775                 780

 Asn Arg Asn Ala Cys Tyr Gln Pro Met Ser Phe Arg Pro Arg Ile
                 785                 790                 795

 Leu Ile Val Gly Glu Pro Gly Phe Gly Gln Gly Ser His Leu Ala
                 800                 805                 810

 Pro Ala Val Ile His Ala Leu Glu Lys Phe Thr Val Tyr Thr Leu
                 815                 820                 825

 Asp Ile Pro Val Leu Phe Gly Val Ser Thr Thr Ser Pro Glu Glu
                 830                 835                 840

 Thr Cys Ala Gln Val Ile Arg Glu Ala Lys Arg Thr Ala Pro Ser
                 845                 850                 855

 Ile Val Tyr Val Pro His Ile His Val Trp Trp Glu Ile Val Gly
                 860                 865                 870

 Pro Thr Leu Lys Ala Thr Phe Thr Thr Leu Leu Gln Asn Ile Pro
                 875                 880                 885

 Ser Phe Ala Pro Val Leu Leu Leu Ala Thr Ser Asp Lys Pro His
                 890                 895                 900

 Ser Ala Leu Pro Glu Glu Val Gln Glu Leu Phe Ile Arg Asp Tyr
                 905                 910                 915

 Gly Glu Ile Phe Asn Val Gln Leu Pro Asp Lys Glu Glu Arg Thr
                 920                 925                 930

 Lys Phe Phe Glu Asp Leu Ile Leu Lys Gln Ala Ala Lys Pro Pro
                 935                 940                 945

 Ile Ser Lys Lys Lys Ala Val Leu Gln Ala Leu Glu Val Leu Pro
                 950                 955                 960

 Val Ala Pro Pro Pro Glu Pro Arg Ser Leu Thr Ala Glu Glu Val
                 965                 970                 975

 Lys Arg Leu Glu Glu Gln Glu Glu Asp Thr Phe Arg Glu Leu Arg
                 980                 985                 990

 Ile Phe Leu Arg Asn Val Thr His Arg Leu Ala Ile Asp Lys Arg
                 995                1000                1005

 Phe Arg Val Phe Thr Lys Pro Val Asp Pro Asp Glu Val Pro Asp
                1010                1015                1020

 Tyr Val Thr Val Ile Lys Gln Pro Met Asp Leu Ser Ser Val Ile
                1025                1030                1035

 Ser Lys Ile Asp Leu His Lys Tyr Leu Thr Val Lys Asp Tyr Leu
                1040                1045                1050

 Arg Asp Ile Asp Leu Ile Cys Ser Asn Ala Leu Glu Tyr Asn Pro
                1055                1060                1065

 Asp Arg Asp Pro Gly Asp Arg Leu Ile Arg His Arg Ala Cys Ala
                1070                1075                1080

 Leu Arg Asp Thr Ala Tyr Ala Ile Ile Lys Glu Glu Leu Asp Glu
                1085                1090                1095

 Asp Phe Glu Gln Leu Cys Glu Glu Ile Gln Glu Ser Arg Lys Lys
                1100                1105                1110

 Arg Gly Cys Ser Ser Ser Lys Tyr Ala Pro Ser Tyr Tyr His Val
                1115                1120                1125

 Met Pro Lys Gln Asn Ser Thr Leu Val Gly Asp Lys Arg Ser Asp
                1130                1135                1140

 Pro Glu Gln Asn Glu Lys Leu Lys Thr Pro Ser Thr Pro Val Ala
                1145                1150                1155

 Cys Ser Thr Pro Ala Gln Leu Lys Arg Lys Ile Arg Lys Lys Ser
                1160                1165                1170

 Asn Trp Tyr Leu Gly Thr Ile Lys Lys Arg Arg Lys Ile Ser Gln
                1175                1180                1185

 Ala Lys Asp Asp Ser Gln Asn Ala Ile Asp His Lys Ile Glu Ser
                1190                1195                1200

 Asp Thr Glu Glu Thr Gln Asp Thr Ser Val Asp His Asn Glu Thr
                1205                1210                1215

 Gly Asn Thr Gly Glu Ser Ser Val Glu Glu Asn Glu Lys Gln Gln
                1220                1225                1230

 Asn Ala Ser Glu Ser Lys Leu Glu Leu Arg Asn Asn Ser Asn Thr
                1235                1240                1245

 Cys Asn Ile Glu Asn Glu Leu Glu Asp Ser Arg Lys Thr Thr Ala
                1250                1255                1260

 Cys Thr Glu Leu Arg Asp Lys Ile Ala Cys Asn Gly Asp Ala Ser
                1265                1270                1275

 Ser Ser Gln Ile Ile His Ile Ser Asp Glu Asn Glu Gly Lys Glu
                1280                1285                1290

 Met Cys Val Leu Arg Met Thr Arg Ala Arg Arg Ser Gln Val Glu
                1295                1300                1305

 Gln Gln Gln Leu Ile Thr Val Glu Lys Ala Leu Ala Ile Leu Ser
                1310                1315                1320

 Gln Pro Thr Pro Ser Leu Val Val Asp His Glu Arg Leu Lys Asn
                1325                1330                1335

 Leu Leu Lys Thr Val Val Lys Lys Ser Gln Asn Tyr Asn Ile Phe
                1340                1345                1350

 Gln Leu Glu Asn Leu Tyr Ala Val Ile Ser Gln Cys Ile Tyr Arg
                1355                1360                1365

 His Arg Lys Asp His Asp Lys Thr Ser Leu Ile Gln Lys Met Glu
                1370                1375                1380

 Gln Glu Val Glu Asn Phe Ser Cys Ser Arg
                1385                1390

<210> 3770
<211> 2085
<212> DNA
<213> Homo sapien

<400> 3770
 ggctgcagtt acagagtgct gccatcacca agtatgtggc ggacgtcctg 50

 ccggggaaga atcaaagagc agagagcatg gccagtgcag cgagggaact 100

 ggttatccag cggttgagtc tggtgaggag tctttgcgag agcgaggagc 150

 agcggttact ggaacaggtg catggcgaag aggagcgggc ccaccagagc 200

 atcctgacac agcgggtgca ctgggccgag gcgctgcaga aacttgacac 250

 catccgcact ggcctggtgg gcatgcttac tcacctggat gacctccagc 300

 tgattcagaa ggagcaagag attttcgaga ggaccgaaga agcagagggc 350

 attttggatc cccaggagtc ggaaatgtta aactttaatg agaagtgcac 400

 tcggagccca ctactgaccc aactctgggc aacggcggtt cttgggtctc 450

 tctcaggcac agaggacata cggatcgatg agaggacagt cagccccttc 500

 ctgcaattgt cagatgatcg aaagaccctg accttcagca ccaagaagtc 550

 aaaggcctgt gcagatggcc cggagcgctt cgaccactgg cccaatgccc 600

 tggctgccac ctccttccag aatgggctcc atgcctggat ggtgaatgtc 650

 cagaacagtt gtgcctataa ggtgggcgtg gcttcaggcc acctgccccg 700

 caagggttct ggcagtgact gccgtctggg ccacaatgcc ttctcctggg 750

 tcttctctcg ctatgatcag gagtttcgtt tctcacacaa tgggcagcac 800

 gagcccctgg ggctgctgcg gggcccagcc cagctgggtg tagtgctgga 850

 cttgcaggtt caggagctgc tcttctatga gccagcctcc ggcatagtgc 900

 tctgtgccca tcatgtgtcc ttcccggggc ccctcttccc agtctttgct 950

 gtggccgatc agaccatttc tatcgtccgc tgacctctgg ccacaggaag 1000

 ccaggtccac cgcccaccac cctttcaggc catgtttcta ctcagtgtgc 1050

 ttttcccaaa tgatgtgtgt ggtgtttcta agagaaacag ggcccataac 1100

 cagtgggcag ctttaggagg gatggggatc tgtttcagat ctaggcataa 1150

 cctgtaaatc acaggtgtcc aaacttttgg cttccctggg ccacatttga 1200

 agaagaattt tcttgggcca cataaaatac actaacgata gctgatgagc 1250

 taaaaaaaaa aaaaaaagtc tgtgtataat ttttgtgata tctgccacca 1300

 cagataagca aaaaagtcct tgcattcaaa gggttggaga ttgctgcttt 1350

 gagtgctggg tacctgtggg gaacctacta ctccctgggc cttagtctcc 1400

 caaatccacc atgcatctgc ccctctgagg gtgtcttcac tttgtctctg 1450

 gcatctagca tggtgcctgg tgcatagtga gcatgcaata aatatttggc 1500

 aggtgagtgg atggatagat ggataggtga atgtaggtgg acaggtgact 1550

 gggtggatgt tgtggtctct ggagaagcac tgccattcag cctcctgctc 1600

 cagctgttca catgcagaaa tgctctcttc acaggcagag aagcctgtgg 1650

 ctaaagtttc cacatcccat taactcagtg cttttgtctt tttcatgaca 1700

 tggcacatag agaaaatatt tttttctagc acacaagagc aacctgaaag 1750

 gctgctcctg gctaggggac tctgtcccgg gggaccgtgt cctcccccat 1800

 gtcctgccta ggccctcaga ggaccagggg atcatgtctc caggtaaccc 1850

 gactgtagcc cctgctggct gagctccagc ctgtgcccac tgataatagc 1900

 agggacggcc tttctcttag agcagctgat aagtttccct acctgatggc 1950

 cccctctgac ataaactgca cacctggggt gatggcttaa agccagaaag 2000

 agctgaggga gttaagaggg ccaaccttag ggcacgtggg cattattaaa 2050

 ggtcttaaaa gcattaaaaa aaaaaaaaaa aaaaa 2085

<210> 3771
<211> 301
<212> PRT
<213> Homo sapien

<400> 3771
 Met Ala Ser Ala Ala Arg Glu Leu Val Ile Gln Arg Leu Ser Leu
   1               5                  10                  15

 Val Arg Ser Leu Cys Glu Ser Glu Glu Gln Arg Leu Leu Glu Gln
                  20                  25                  30

 Val His Gly Glu Glu Glu Arg Ala His Gln Ser Ile Leu Thr Gln
                  35                  40                  45

 Arg Val His Trp Ala Glu Ala Leu Gln Lys Leu Asp Thr Ile Arg
                  50                  55                  60

 Thr Gly Leu Val Gly Met Leu Thr His Leu Asp Asp Leu Gln Leu
                  65                  70                  75

 Ile Gln Lys Glu Gln Glu Ile Phe Glu Arg Thr Glu Glu Ala Glu
                  80                  85                  90

 Gly Ile Leu Asp Pro Gln Glu Ser Glu Met Leu Asn Phe Asn Glu
                  95                 100                 105

 Lys Cys Thr Arg Ser Pro Leu Leu Thr Gln Leu Trp Ala Thr Ala
                 110                 115                 120

 Val Leu Gly Ser Leu Ser Gly Thr Glu Asp Ile Arg Ile Asp Glu
                 125                 130                 135

 Arg Thr Val Ser Pro Phe Leu Gln Leu Ser Asp Asp Arg Lys Thr
                 140                 145                 150

 Leu Thr Phe Ser Thr Lys Lys Ser Lys Ala Cys Ala Asp Gly Pro
                 155                 160                 165

 Glu Arg Phe Asp His Trp Pro Asn Ala Leu Ala Ala Thr Ser Phe
                 170                 175                 180

 Gln Asn Gly Leu His Ala Trp Met Val Asn Val Gln Asn Ser Cys
                 185                 190                 195

 Ala Tyr Lys Val Gly Val Ala Ser Gly His Leu Pro Arg Lys Gly
                 200                 205                 210

 Ser Gly Ser Asp Cys Arg Leu Gly His Asn Ala Phe Ser Trp Val
                 215                 220                 225

 Phe Ser Arg Tyr Asp Gln Glu Phe Arg Phe Ser His Asn Gly Gln
                 230                 235                 240

 His Glu Pro Leu Gly Leu Leu Arg Gly Pro Ala Gln Leu Gly Val
                 245                 250                 255

 Val Leu Asp Leu Gln Val Gln Glu Leu Leu Phe Tyr Glu Pro Ala
                 260                 265                 270

 Ser Gly Ile Val Leu Cys Ala His His Val Ser Phe Pro Gly Pro
                 275                 280                 285

 Leu Phe Pro Val Phe Ala Val Ala Asp Gln Thr Ile Ser Ile Val
                 290                 295                 300

 Arg


<210> 3772
<211> 3857
<212> DNA
<213> Homo sapien

<400> 3772
 agtaacgcct tctccaagtg gatggcgggg tggacacgcg tcccggcgcc 50

 ccgggctccc tgggatatgt agttcgcgac aggacgagcg gaaatactgc 100

 caggatttta ccacctctcg cccatttatt tacttctcgg tcaccgcttt 150

 cgggggacag ataaacacca cagatgccca tcaaaggggc gcacgggtct 200

 ggaggcgcag ctcaggtttt tgcgttggtc accctgccct ccgcacgtgg 250

 agagggcagg cataaagcac cttgaaagga aggtgctgtc aatgctatcc 300

 gacgacctgt cgccgggcac cgcagcatcc tcgctcgctc cgatgggacg 350

 agggacgccg gccccagggt aacaggaggc gcctcgccgg ccgcgcgctg 400

 gatgctgtga tccaggtccg gagccgggtt ccgccgcggc cgcagcgacc 450

 cgaccccacc cgacaggcca gaggaatcag tttagacttg aaattcagtt 500

 tttcctgaaa ctgatcagaa gttagtgaca ccttgattgg atccgttttt 550

 ctgtcaggag ctcattttgc agctctcaag cttttatagc atgctgtaaa 600

 caattgtcaa agttgtttat caagaaacag atagagttgc aacttgtttc 650

 tagtaataga aacttttaca ctgcattcaa tgcctaacgt tgcagaaaca 700

 gaaaggtcaa atgattctgg aaatggtgag cacaaatctg agagaaagtc 750

 acctgaagag aatctacaag gtgctgtaaa atctttctgc acaagtgcct 800

 caggagcacc cttgggtccc aaaggagatg gtcattatcc atggagttgt 850

 ccagtgactc atacacggga aaaaatttat gccatctgtt cggactatgc 900

 ctttctcaac caggcgacct caatctataa aactccaaat ccatcccgct 950

 ctccttgcct ccctgatagt acctctttat ctgctggaaa taattcatca 1000

 agatacattg gtatcccgac tagtacatcg gaaattatct acaatgaaga 1050

 aaatagcttg gaaaacttat ccaacagcct gggcaagcta cctctcgcat 1100

 gggaaattga taaatctgaa tttgatgggg tgaccacaaa ttcgaaacac 1150

 aaatcaggca atgcaaagaa acaagtttcc aagagaaaaa cttcagataa 1200

 aaagggaaga tatcagaagg aatgtcctca gcattctcct cttgaagata 1250

 ttaaacagcg gaaagtatta gacctcagac gatggtactg cataagccga 1300

 ccacagtata agacttcttg tggcatctct tcattaattt cttgttggaa 1350

 tttcttatac agcacaatgg gagctggaaa ccttccacct attacccaag 1400

 aagaagcttt acatattctg ggctttcaac ctccatttga agatattagg 1450

 tttggtcctt tcacggggaa tacaacactt atgaggtggt ttagacaaat 1500

 taatgaccac ttccatgtaa aaggatgctc ttatgttcta tataagcctc 1550

 atgggaagaa taaaacagca ggagaaactg cttcaggggc cctgtcaaag 1600

 ttaacccgtg gattgaaaga tgaatcgctg gcttatatct atcattgcca 1650

 aaatcattat ttttgtccaa ttggcttcga agcaacccct gttaaagcta 1700

 ataaagcatt cagcagggga cctctctcac cacaggaagt tgaatattgg 1750

 atcttaattg gagaatcaag tagaaaacat cctgccattc actgtaaaaa 1800

 atgggcagat attgttactg atctaaacac tcaaaatcca gaatacctgg 1850

 atatccggca cttagagagg ggactgcagt atagaaaaac aaagaaggtt 1900

 gggggaaatt tgcattgcat catagcattc cagagactta actggcaaag 1950

 atttggcctt tggaactttc catttggaac cattagacaa gaatcacaac 2000

 ctccaacaca tgcccaggga attgccaaat ctgagagtga agacaatatt 2050

 tccaagaagc agcatgggcg tctgggccgg tctttcagtg ctagtttcca 2100

 tcaggactcg gcatggaaaa agatgtctag tatccatgag agaaggaaca 2150

 gtggttacca gggttacagt gattacgatg ggaatgattg actatgcttg 2200

 ctactgaaca gctggcatta tatatgaaac tgctatatac aggactgtat 2250

 aaagacagta gaagatttta gtaagcctac attaaatagg agcagatctt 2300

 gtggtataaa aaataacctt gtagttctcc agatactaag cttgtatatg 2350

 attatggtgg gtgatttcag atatataagc agataagcac agattattgt 2400

 cctttcaagt taagagtata taatctggac agaaaatttc acaaaattca 2450

 ataaaattac aactgttgtc taaataagtg aaacacaaat tcacttaata 2500

 gcatcaagat ttgaaatact taagcatgaa gtgactttta taatgactcg 2550

 atccctagac atttgttaca gatagtttta tgcctaagac caagatgtaa 2600

 agtaccatct gcccttaaaa aaaattgggg ctgtcaattt ctagttttca 2650

 ctcatggtta acacgcattt aaaattattt catgagtcta gtagttcttt 2700

 gatttatagc aggatcttgc ttgcctcatt tgtttcctgg ttatgttctt 2750

 aggattctga ctaagaggca aaagagaaaa gactcaagaa actgatcctg 2800

 gagatcgaga ccatcctggc taacatggtg aaaccccgtc tctactaaac 2850

 atacaaaaaa ttagccgggt gtagtggtgg gcacctgtag tcctagctac 2900

 tcgagaggct gaggcaggag aatggcgtga acccgggagg tggagcttgc 2950

 agtgagcgga gatcgcgcca ctgcactcca gcctgggcga cagggcaaga 3000

 ctctgtctca aaaaaaaaaa aaaaaaaaaa gacggatcct tttttttggt 3050

 gcaaatgggt gacttagtgc attgattcag atttttaaaa tttcttgatg 3100

 tggtttgtaa taatcaaata ttgacaagaa ccttaggtct cgaaagactt 3150

 ttataagtct agatgacgtt tgccttaggg gtaaagtaaa agaacaattg 3200

 gcaccttaag tttctatacc caaggttatc tgtgaaatga gatctcctga 3250

 tatttgattg ctttctcagt atggagtcat atgttgataa cagtactgaa 3300

 gatgcataag aaatgcccaa gtcactcaga ggacaactac ccatattcca 3350

 gactctgagc tgtttccttt ttaaaaatca tatagacaat tagctgtttg 3400

 aagtgagtat taaatatttc agaagtgtga atttcatgta tttgagctcc 3450

 tctagttgct gttggttttt cttctgctgc caacctgtga ctcacaaatg 3500

 actaggatct cttgttcttt aattttaggg tcttgttcca ggactcaaat 3550

 cagtaacttg gtgattacaa ggtgctgaat gtgttggtaa ccatatcgca 3600

 atacacctca aggaaaaggt tcagattttt atttttaaaa tattttcatt 3650

 tttttcttga attttatatc cgtttgttca ctcgtacatg cctagcctac 3700

 agaaggggat atatattatg aaatggtcat ttttctgaag agaatatttt 3750

 gcttgaaatg caaaggactg aaagagattt gtaggttgtt gattttgtta 3800

 cttcatactg gaacttttaa aaagatttca tcaaataaag ttttgttttc 3850

 tactttt 3857

<210> 3773
<211> 503
<212> PRT
<213> Homo sapien

<400> 3773
 Met Pro Asn Val Ala Glu Thr Glu Arg Ser Asn Asp Ser Gly Asn
   1               5                  10                  15

 Gly Glu His Lys Ser Glu Arg Lys Ser Pro Glu Glu Asn Leu Gln
                  20                  25                  30

 Gly Ala Val Lys Ser Phe Cys Thr Ser Ala Ser Gly Ala Pro Leu
                  35                  40                  45

 Gly Pro Lys Gly Asp Gly His Tyr Pro Trp Ser Cys Pro Val Thr
                  50                  55                  60

 His Thr Arg Glu Lys Ile Tyr Ala Ile Cys Ser Asp Tyr Ala Phe
                  65                  70                  75

 Leu Asn Gln Ala Thr Ser Ile Tyr Lys Thr Pro Asn Pro Ser Arg
                  80                  85                  90

 Ser Pro Cys Leu Pro Asp Ser Thr Ser Leu Ser Ala Gly Asn Asn
                  95                 100                 105

 Ser Ser Arg Tyr Ile Gly Ile Pro Thr Ser Thr Ser Glu Ile Ile
                 110                 115                 120

 Tyr Asn Glu Glu Asn Ser Leu Glu Asn Leu Ser Asn Ser Leu Gly
                 125                 130                 135

 Lys Leu Pro Leu Ala Trp Glu Ile Asp Lys Ser Glu Phe Asp Gly
                 140                 145                 150

 Val Thr Thr Asn Ser Lys His Lys Ser Gly Asn Ala Lys Lys Gln
                 155                 160                 165

 Val Ser Lys Arg Lys Thr Ser Asp Lys Lys Gly Arg Tyr Gln Lys
                 170                 175                 180

 Glu Cys Pro Gln His Ser Pro Leu Glu Asp Ile Lys Gln Arg Lys
                 185                 190                 195

 Val Leu Asp Leu Arg Arg Trp Tyr Cys Ile Ser Arg Pro Gln Tyr
                 200                 205                 210

 Lys Thr Ser Cys Gly Ile Ser Ser Leu Ile Ser Cys Trp Asn Phe
                 215                 220                 225

 Leu Tyr Ser Thr Met Gly Ala Gly Asn Leu Pro Pro Ile Thr Gln
                 230                 235                 240

 Glu Glu Ala Leu His Ile Leu Gly Phe Gln Pro Pro Phe Glu Asp
                 245                 250                 255

 Ile Arg Phe Gly Pro Phe Thr Gly Asn Thr Thr Leu Met Arg Trp
                 260                 265                 270

 Phe Arg Gln Ile Asn Asp His Phe His Val Lys Gly Cys Ser Tyr
                 275                 280                 285

 Val Leu Tyr Lys Pro His Gly Lys Asn Lys Thr Ala Gly Glu Thr
                 290                 295                 300

 Ala Ser Gly Ala Leu Ser Lys Leu Thr Arg Gly Leu Lys Asp Glu
                 305                 310                 315

 Ser Leu Ala Tyr Ile Tyr His Cys Gln Asn His Tyr Phe Cys Pro
                 320                 325                 330

 Ile Gly Phe Glu Ala Thr Pro Val Lys Ala Asn Lys Ala Phe Ser
                 335                 340                 345

 Arg Gly Pro Leu Ser Pro Gln Glu Val Glu Tyr Trp Ile Leu Ile
                 350                 355                 360

 Gly Glu Ser Ser Arg Lys His Pro Ala Ile His Cys Lys Lys Trp
                 365                 370                 375

 Ala Asp Ile Val Thr Asp Leu Asn Thr Gln Asn Pro Glu Tyr Leu
                 380                 385                 390

 Asp Ile Arg His Leu Glu Arg Gly Leu Gln Tyr Arg Lys Thr Lys
                 395                 400                 405

 Lys Val Gly Gly Asn Leu His Cys Ile Ile Ala Phe Gln Arg Leu
                 410                 415                 420

 Asn Trp Gln Arg Phe Gly Leu Trp Asn Phe Pro Phe Gly Thr Ile
                 425                 430                 435

 Arg Gln Glu Ser Gln Pro Pro Thr His Ala Gln Gly Ile Ala Lys
                 440                 445                 450

 Ser Glu Ser Glu Asp Asn Ile Ser Lys Lys Gln His Gly Arg Leu
                 455                 460                 465

 Gly Arg Ser Phe Ser Ala Ser Phe His Gln Asp Ser Ala Trp Lys
                 470                 475                 480

 Lys Met Ser Ser Ile His Glu Arg Arg Asn Ser Gly Tyr Gln Gly
                 485                 490                 495

 Tyr Ser Asp Tyr Asp Gly Asn Asp
                 500

<210> 3774
<211> 1192
<212> DNA
<213> Homo sapien

<400> 3774
 agagcgtgcg ttcggtggcc cataggggaa gatggcggct gctcctttgg 50

 aggagcggga ttgagaggat cggggtgggg agaccaaaca agagagacat 100

 ttctggctct gaaggcgaac gcttcgctgg ccatttagga gctctgctca 150

 aagccagacg tatcctagaa ggaaaacatc accatggcta cagaaattgg 200

 ttctcctcct cgttttttcc atatgccaag gttccagcac caggcacctc 250

 gacagctgtt ttataagcga cctgattttg cacaacagca agcaatgcaa 300

 cagcttactt ttgatggaaa acgaatgaga aaagctgtga accgaaaaac 350

 catagactac aatccatctg taattaagta tttggagaac agaatatggc 400

 aaagagacca gagagatatg cgggcaattc agcctgatgc aggttattac 450

 aatgatctgg tcccacctat aggaatgttg aataatccta tgaatgcagt 500

 aacaacaaaa tttgttcgga catcaacaaa taaagtaaag tgtcctgtat 550

 ttgttgttag gtggactcca gaaggaagac gcttggtcac tggagcttct 600

 agtggggagt ttaccctgtg gaatggactc actttcaatt ttgaaacaat 650

 attacaggct cacgacagcc cagtgagggc catgacgtgg tcacataatg 700

 acatgtggat gttgacagca gaccacggag gatatgtgaa atattggcag 750

 tcgaacatga acaacgtcaa gatgttccag gcacataagg aggcgattag 800

 agaggccagg tttatacaca atataccatt ttctgtagtc cctattgtca 850

 tggttaaatt attctctaag tgtattctgg gtgcagagat gcatgggctc 900

 tgtcagtttc tgggaaactt tctgcaccct ataaacacaa tatttttctt 950

 tgttttcaca cattcaccat tttgctggca cctttctgaa gtagtgttgt 1000

 cccggtatca gcctttgcaa tatgttagag atgtactgtc tgccgcattt 1050

 tgcactggtt ttctcttttc atttatgatt aataatgtgt atacgttatc 1100

 cctttttatt atctactgtg taagacaaga atatttcatt ccaaataaag 1150

 aattcagtct tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1192

<210> 3775
<211> 335
<212> PRT
<213> Homo sapien

<400> 3775
 Met Ala Thr Glu Ile Gly Ser Pro Pro Arg Phe Phe His Met Pro
   1               5                  10                  15

 Arg Phe Gln His Gln Ala Pro Arg Gln Leu Phe Tyr Lys Arg Pro
                  20                  25                  30

 Asp Phe Ala Gln Gln Gln Ala Met Gln Gln Leu Thr Phe Asp Gly
                  35                  40                  45

 Lys Arg Met Arg Lys Ala Val Asn Arg Lys Thr Ile Asp Tyr Asn
                  50                  55                  60

 Pro Ser Val Ile Lys Tyr Leu Glu Asn Arg Ile Trp Gln Arg Asp
                  65                  70                  75

 Gln Arg Asp Met Arg Ala Ile Gln Pro Asp Ala Gly Tyr Tyr Asn
                  80                  85                  90

 Asp Leu Val Pro Pro Ile Gly Met Leu Asn Asn Pro Met Asn Ala
                  95                 100                 105

 Val Thr Thr Lys Phe Val Arg Thr Ser Thr Asn Lys Val Lys Cys
                 110                 115                 120

 Pro Val Phe Val Val Arg Trp Thr Pro Glu Gly Arg Arg Leu Val
                 125                 130                 135

 Thr Gly Ala Ser Ser Gly Glu Phe Thr Leu Trp Asn Gly Leu Thr
                 140                 145                 150

 Phe Asn Phe Glu Thr Ile Leu Gln Ala His Asp Ser Pro Val Arg
                 155                 160                 165

 Ala Met Thr Trp Ser His Asn Asp Met Trp Met Leu Thr Ala Asp
                 170                 175                 180

 His Gly Gly Tyr Val Lys Tyr Trp Gln Ser Asn Met Asn Asn Val
                 185                 190                 195

 Lys Met Phe Gln Ala His Lys Glu Ala Ile Arg Glu Ala Arg Phe
                 200                 205                 210

 Ile His Asn Ile Pro Phe Ser Val Val Pro Ile Val Met Val Lys
                 215                 220                 225

 Leu Phe Ser Lys Cys Ile Leu Gly Ala Glu Met His Gly Leu Cys
                 230                 235                 240

 Gln Phe Leu Gly Asn Phe Leu His Pro Ile Asn Thr Ile Phe Phe
                 245                 250                 255

 Phe Val Phe Thr His Ser Pro Phe Cys Trp His Leu Ser Glu Val
                 260                 265                 270

 Val Leu Ser Arg Tyr Gln Pro Leu Gln Tyr Val Arg Asp Val Leu
                 275                 280                 285

 Ser Ala Ala Phe Cys Thr Gly Phe Leu Phe Ser Phe Met Ile Asn
                 290                 295                 300

 Asn Val Tyr Thr Leu Ser Leu Phe Ile Ile Tyr Cys Val Arg Gln
                 305                 310                 315

 Glu Tyr Phe Ile Pro Asn Lys Glu Phe Ser Leu Glu Lys Lys Lys
                 320                 325                 330

 Lys Lys Lys Lys Lys
                 335

<210> 3776
<211> 3653
<212> DNA
<213> Homo sapien

<400> 3776
 acgcggcgct cgcgctccct ccttaaatga gcctgggcgc cccgcgcccg 50

 ccacttcagt ggatcccgcg ccggggccgc gggcggagct gcctgccggt 100

 cccgcgccgc gcgtccgcac tcctcggccc tcgggcggtc gatgggacgg 150

 ggcgccgcgg agcaggaggc ggcgcccgtc ggggtgctcg ggccgcgcgg 200

 gagcccactg tggggctcgg gcatggcggg ccgcaggacc tgagctctcc 250

 tcaggggagc ggggaggcag ctgctggccg gcgatgggga cggagtgggg 300

 ccgtcgccgc cgcgccgagc cgtgagcgcc gagccaccgc cgccgctacc 350

 tcagcccttc gcgaagcgcc gggcagctcg ggaacatggc cctggagcgg 400

 ctctgctcgg tcctcaaagt gttgttaata acagtactgg tagtggaagg 450

 gattgccgtg gcccaaaaaa cccaagatgg acaaaatatt ggaatcaagc 500

 atattcctgc aacccagtgt ggcatttggg ttcgaaccag caatggaggt 550

 cattttgctt cgccaaatta tcctgactca tatccaccaa acaaggagtg 600

 tatctacatt ttggaagctg ctccacgtca aagaatagag ttgacctttg 650

 atgaacatta ttatatagaa ccatcatttg agtgtcggtt tgatcacttg 700

 gaagttcgag atgggccatt tggtttctct cctcttatag atcgttactg 750

 tggcgtgaaa agccctccat taattagatc aacagggaga ttcatgtgga 800

 ttaagtttag ttctgatgaa gagcttgaag gactgggatt tcgagcaaaa 850

 tattcattta ttccagatcc agactttact tacctaggag gtattttaaa 900

 tcccattcca gattgtcagt tcgagctctc gggagctgat ggaatagtgc 950

 gctctagtca ggtagaacaa gaggagaaaa caaaaccagg ccaagccgtt 1000

 gattgcatct ggaccattaa agccactcca aaagctaaga tttatttgag 1050

 gttcctagat tatcaaatgg agcactcaaa tgaatgcaag agaaacttcg 1100

 ttgcagtcta tgatggaagc agttctattg aaaacctgaa ggccaagttt 1150

 tgcagcactg tggccaatga tgtaatgctt aaaacaggaa ttggagtgat 1200

 tcgaatgtgg gcagatgaag gtagtcggct tagcaggttt cgaatgctct 1250

 ttacttcctt tgtggagcct ccctgcacaa gcagcacttt cttttgccat 1300

 agcaacatgt gcatcaataa ttctttagtc tgtaatggtg tccaaaattg 1350

 tgcataccct tgggatgaaa atcattgtaa agaaaagaaa aaagcaggag 1400

 tatttgaaca aatcactaag actcatggaa caattattgg cattacttca 1450

 gggattgtct tggtccttct cattatttct attttagtac aagtgaaaca 1500

 gcctcgaaaa aaggtcatgg cttgcaaaac cgcttttaat aaaaccgggt 1550

 tccaagaagt gtttgatcct cctcattatg aactgttttc actaagggac 1600

 aaagagattt ctgcagacct ggcagacttg tcggaagaat tggacaacta 1650

 ccagaagatg cggcgctcct ccaccgcctc ccgctgcatc cacgaccacc 1700

 actgtgggtc gcaggcctcc agcgtcaaac aaagcaggac caacctcagt 1750

 tccatggaac ttcctttccg aaatgacttt gcacaaccac agccaatgaa 1800

 aacatttaat agcaccttca agaaaagtag ttacactttc aaacagggac 1850

 atgagtgccc tgagcaggcc ctggaagacc gagtaatgga ggagattccc 1900

 tgtgaaattt atgtcagggg gcgagaagat tctgcacaag catccatatc 1950

 cattgacttc taatcttctg ctaatggtga tgtgaattct tagggtgtgt 2000

 acgtacgcag cctccagggc accatactgt ttccagcagc caaccctttt 2050

 ctcccatcac aactacgaag accttgattt accgttaacc tattgtatgg 2100

 tgatgttttt attctctcag gcagtctata tatgttaaac caatcaagga 2150

 acttactcta ttcagtggaa acaataatca tctctattgc ttggtgtcat 2200

 ttataggaag cactgccagt taaagagcat tagaagaggt ggttggatgg 2250

 agccaggctc aggctgcctc ttcgttttag caacaagaag actgctcttg 2300

 actgataaca gctctgtcaa tattttgatg ccacaataaa cttgattttt 2350

 ctttacattc cttttatttt tcctttctct aaatttaatt tgttttataa 2400

 gcctatcgtt ttaccatttc attttcttac ataagtacaa gtggttaatg 2450

 taccacatac ttcagtatag gcatttgttc ttgagtgtgt caaaatacag 2500

 ctagttactg tgccaattaa gacccagttg tatttcaccc atctgtttct 2550

 tcttggctaa tctctgtact tctgcctttt aattactggg cccttattcc 2600

 ttattttctg tgagaaataa tagatgatat gatttattac ctttcaatta 2650

 tatttttctc agttatacta gaaaatttca taatcctggg atatatgtac 2700

 cattgtcagc tatgactaaa aatttgaaaa agataaaaat ttctagcaag 2750

 cctttgaagt ttaccaagta tagtcacatt cagtgacagc ccattcattc 2800

 cagtaaagaa tcatttcatt cactttggga gaggcctata attacattta 2850

 tttgcaatgt ttctcttcgc tagattgtta catagctccc attctgttgg 2900

 ttttgcttac agcatatggt aaccaaggtt agatgccagt taaaattcct 2950

 tagaaattgg atgagccttg agattgcttc ttaactggga catgacattt 3000

 ttctagctct tatcaagaat aacaacttcc actttttttt aaactgcact 3050

 tttgactttt tttatggtat aaaaacaata atttataaac ataaaagctc 3100

 attgtgtttt ttagactttt gatattattt gatactgtac aaactttatt 3150

 aaatcaagat gaaagaccta caggacagat tcctttcagt gttcacatca 3200

 gtggctttgt atgcaaatat gctgtgttgg acctggacgc tataacttat 3250

 tgtaaagacc ttggaaatgt ggacataagc tctttctttc cttttgttac 3300

 tgtatttagt ttgtgataaa tttttcactg tgtgatattt atgctctaaa 3350

 tcactacaca aatcccatat taaaatatac attgtacctg accctttaat 3400

 catgttattt atgccaccaa ggttgtggat cttaaggtat gtatggaaag 3450

 gaactcattt atcaaattgt aagtaataca gacatgccat ttaaaagagg 3500

 taaattcttg ttttctatat tttgttagta aattctcaat gaaataagtt 3550

 gaagtttcac tggatttcat taacttttaa atattacata tatgtgtttt 3600

 ctcagattag tgaaaattgt gaccttaaat ttaatacaca tatactgcct 3650

 cag 3653

<210> 3777
<211> 525
<212> PRT
<213> Homo sapien

<400> 3777
 Met Ala Leu Glu Arg Leu Cys Ser Val Leu Lys Val Leu Leu Ile
   1               5                  10                  15

 Thr Val Leu Val Val Glu Gly Ile Ala Val Ala Gln Lys Thr Gln
                  20                  25                  30

 Asp Gly Gln Asn Ile Gly Ile Lys His Ile Pro Ala Thr Gln Cys
                  35                  40                  45

 Gly Ile Trp Val Arg Thr Ser Asn Gly Gly His Phe Ala Ser Pro
                  50                  55                  60

 Asn Tyr Pro Asp Ser Tyr Pro Pro Asn Lys Glu Cys Ile Tyr Ile
                  65                  70                  75

 Leu Glu Ala Ala Pro Arg Gln Arg Ile Glu Leu Thr Phe Asp Glu
                  80                  85                  90

 His Tyr Tyr Ile Glu Pro Ser Phe Glu Cys Arg Phe Asp His Leu
                  95                 100                 105

 Glu Val Arg Asp Gly Pro Phe Gly Phe Ser Pro Leu Ile Asp Arg
                 110                 115                 120

 Tyr Cys Gly Val Lys Ser Pro Pro Leu Ile Arg Ser Thr Gly Arg
                 125                 130                 135

 Phe Met Trp Ile Lys Phe Ser Ser Asp Glu Glu Leu Glu Gly Leu
                 140                 145                 150

 Gly Phe Arg Ala Lys Tyr Ser Phe Ile Pro Asp Pro Asp Phe Thr
                 155                 160                 165

 Tyr Leu Gly Gly Ile Leu Asn Pro Ile Pro Asp Cys Gln Phe Glu
                 170                 175                 180

 Leu Ser Gly Ala Asp Gly Ile Val Arg Ser Ser Gln Val Glu Gln
                 185                 190                 195

 Glu Glu Lys Thr Lys Pro Gly Gln Ala Val Asp Cys Ile Trp Thr
                 200                 205                 210

 Ile Lys Ala Thr Pro Lys Ala Lys Ile Tyr Leu Arg Phe Leu Asp
                 215                 220                 225

 Tyr Gln Met Glu His Ser Asn Glu Cys Lys Arg Asn Phe Val Ala
                 230                 235                 240

 Val Tyr Asp Gly Ser Ser Ser Ile Glu Asn Leu Lys Ala Lys Phe
                 245                 250                 255

 Cys Ser Thr Val Ala Asn Asp Val Met Leu Lys Thr Gly Ile Gly
                 260                 265                 270

 Val Ile Arg Met Trp Ala Asp Glu Gly Ser Arg Leu Ser Arg Phe
                 275                 280                 285

 Arg Met Leu Phe Thr Ser Phe Val Glu Pro Pro Cys Thr Ser Ser
                 290                 295                 300

 Thr Phe Phe Cys His Ser Asn Met Cys Ile Asn Asn Ser Leu Val
                 305                 310                 315

 Cys Asn Gly Val Gln Asn Cys Ala Tyr Pro Trp Asp Glu Asn His
                 320                 325                 330

 Cys Lys Glu Lys Lys Lys Ala Gly Val Phe Glu Gln Ile Thr Lys
                 335                 340                 345

 Thr His Gly Thr Ile Ile Gly Ile Thr Ser Gly Ile Val Leu Val
                 350                 355                 360

 Leu Leu Ile Ile Ser Ile Leu Val Gln Val Lys Gln Pro Arg Lys
                 365                 370                 375

 Lys Val Met Ala Cys Lys Thr Ala Phe Asn Lys Thr Gly Phe Gln
                 380                 385                 390

 Glu Val Phe Asp Pro Pro His Tyr Glu Leu Phe Ser Leu Arg Asp
                 395                 400                 405

 Lys Glu Ile Ser Ala Asp Leu Ala Asp Leu Ser Glu Glu Leu Asp
                 410                 415                 420

 Asn Tyr Gln Lys Met Arg Arg Ser Ser Thr Ala Ser Arg Cys Ile
                 425                 430                 435

 His Asp His His Cys Gly Ser Gln Ala Ser Ser Val Lys Gln Ser
                 440                 445                 450

 Arg Thr Asn Leu Ser Ser Met Glu Leu Pro Phe Arg Asn Asp Phe
                 455                 460                 465

 Ala Gln Pro Gln Pro Met Lys Thr Phe Asn Ser Thr Phe Lys Lys
                 470                 475                 480

 Ser Ser Tyr Thr Phe Lys Gln Gly His Glu Cys Pro Glu Gln Ala
                 485                 490                 495

 Leu Glu Asp Arg Val Met Glu Glu Ile Pro Cys Glu Ile Tyr Val
                 500                 505                 510

 Arg Gly Arg Glu Asp Ser Ala Gln Ala Ser Ile Ser Ile Asp Phe
                 515                 520                 525

<210> 3778
<211> 6461
<212> DNA
<213> Homo sapien

<400> 3778
 agcggacggc ggccgcgcgc tccaggccgg tcgctccacg ccccggctcc 50

 cgggactgtg gactccacga ccctgtcctc ggccctgtcc gcgccgaagc 100

 agcccgggac tgcgcagcgc cccgcgtgcc gatcttttcc taattcagca 150

 gcgatttaac caagagcctg gaatatttta aggagtaata agagacattt 200

 acaaactatt ctctctgaag cctgctacct ggaggcatca tctagataat 250

 cagaaccttg gcttccacat cctcctccct tgtcttaact acaaacattt 300

 ctttctgctg acttcaactc ctcagacatg ggaaagtctc tttctcattt 350

 gcctttgcat tcaagcaaag aagatgctta tgatggagtc acatctgaaa 400

 acatgaggaa tggactggtt aatagtgaag tccataatga agatggaaga 450

 aatggagatg tctctcagtt tccatatgtg gaatttacag gaagagatag 500

 tgtcacctgc cctacttgtc agggaacagg aagaattcct agggggcaag 550

 aaaaccaact ggtggcattg attccatata gtgatcagag attaaggcca 600

 agaagaacaa agctgtatgt gatggcttct gtgtttgtct gtctactcct 650

 ttctggattg gctgtgtttt tccttttccc tcgctctatc gacgtgaaat 700

 acattggtgt aaaatcagcc tatgtcagtt atgatgttca gaagcgtaca 750

 atttatttaa atatcacaaa cacactaaat ataacaaaca ataactatta 800

 ctctgtcgaa gttgaaaaca tcactgccca agttcaattt tcaaaaacag 850

 ttattggaaa ggcacgctta aacaacataa ccattattgg tccacttgat 900

 atgaaacaaa ttgattacac agtacctacc gttatagcag aggaaatgag 950

 ttatatgtat gatttctgta ctctgatatc catcaaagtg cataacatag 1000

 tactcatgat gcaagttact gtgacaacaa catactttgg ccactctgaa 1050

 cagatatccc aggagaggta tcagtatgtc gactgtggaa gaaacacaac 1100

 ttatcagttg gggcagtctg aatatttaaa tgtacttcag ccacaacagt 1150

 aaaaactgga agagatggat ttaaagaaga aatatctatt gatatttcct 1200

 atactctcaa tgaagaggta tttcctaata ggagacctta aattgaacaa 1250

 acctaaagtt tacacttcta agagtacagt taaaagtatg tggacctgca 1300

 gttcttgtaa ctctccactc tgtgttaatg atatatttgt actaggatct 1350

 tttacttgaa tctaaattta ctggttgatt tccttctcca gcctatcccc 1400

 tacagggaaa agctgatact tcccctatag tacaataaat aattatttaa 1450

 aagtcatagc tccagtcact actgaaaaca taattttggt gataaacata 1500

 atttgagaaa cttaatttct gaatgttttt atagaaaatt actgaaagtc 1550

 tattactcat ggaagacttt taaagaataa ccttttttcc tgttttataa 1600

 attcccattg ttatatggta gtatttcagc tacacaatat tttagctttt 1650

 agctagacat ttatagcttt tcatttgttg aaatggtaat catctgcatg 1700

 tttttgtcac ttatttcagg ttagtgattg cctaacactt ataagccaaa 1750

 ataatccttg caaaattcca tacctaaaat tttgaaagcc cctaatgttt 1800

 tcacacatct ttctgtatta gttatagttt tgtgaaatct ttgtgtgatc 1850

 ttcaaacatt atcatttaat gtacaatact gtaaataaac tgtgcatggc 1900

 ttttatacag ctttagtaaa tgtcaaataa agtggtacag actcattaca 1950

 acaagtttct cataaaaata caataaatag gaaaatgaaa ttcagaaacc 2000

 catagactgg gaataggttc cagttacagc ttggatctgg cataaaataa 2050

 atttgaaata aaatattttg atgctccatt tttttatgtt gcttttcata 2100

 ctaaagaatg gtgtagacat gttttgcaac tgttaggtac ccagttatca 2150

 attttatcaa tgttttagag gaggaaatta tttttttggt agaaattgtt 2200

 caagaaatcc ttaattgaat gtcattaaat gatggtggcc aaaataaaac 2250

 ctatttagaa atttaatcac tttgcacatc acttggaata tgatgcctct 2300

 agtagttact tttttatagt tttctacttt tggttttatt taaaattgtt 2350

 ttcaaatata gattattgac ttattcaact ttgctgtttt atattttcag 2400

 tatcattttt catttttttt tttttttttt tttgtctttt cacttaccaa 2450

 gttctaggga catttaaaat atgtactaag tgtaggagtg gttatgatac 2500

 caaaaaatgt agctgggttg agattaattt cgttctgttt tctcatgaca 2550

 gaaatcaggt ttccctttcc ccacccctaa gtgcctaact taggtctgaa 2600

 acagcctgtt tattagtctg actctctcaa ccataaaaca taagctttat 2650

 ttaattctgc ctttaaacac actcaggttt ccccttaatt ttcatattat 2700

 tttctgcaag ttttcttgag tatcttcaat tcgttgaatg tggtttttgg 2750

 tttttttttg ttttaacact agtcttccct taattcattg ctaactcaag 2800

 ccatccttac tattaaaccc aaatcagtcc tttaagttca ttatggcctt 2850

 tctagtattt aaaaaaaaaa aaatcatttt catttttctt ctgctacgtt 2900

 tcctgactac tactgcatac ttctctgata caggttctgt ttgtattttt 2950

 tatatcattc tcattttctc atttgacatg atctatgtct atatatgata 3000

 taggtcccct tttgtctcaa aatttttaat tatgtgactt caaaaatcac 3050

 ctgtatctgt agtagggctt ccaaatctgc ttctccatat gtgaccagtc 3100

 acctgtctgc tttcacattt agctagtgaa ctacacattt actaaaatgt 3150

 gtaaatttta cacatttagt gactgtgtaa aataaaaaaa aagttatttt 3200

 atcatatcct ttctattatg ttcccatcct gtcctcatgt cccatttact 3250

 ttattatcac aattcatttc ttcaaaatta tcttttagat acgctcatac 3300

 aaaaatcaat ccttgttttc ttgcttgtgt cttttaacct tggaaaatta 3350

 catcgtgtaa attaaacaga tttttctgat gatctgtgct tcttatatac 3400

 tattagagtg catgatagta tctcctgaaa aggatggaaa gtagaagcat 3450

 ttgcttttag tcacttaatt ttgaatcttt tttcttcatc ttttgaatta 3500

 atttttttta ttatatctac ttttagtgga gtttgagtca gaaaaaaaca 3550

 agaatttgaa acaagtaaaa agatagaaga gaaataaaga tggtatgtga 3600

 ctactttcag agagagttaa gtaactgtca gaataagcct ggaacaaaac 3650

 aggctgtaaa ttaataaaac tacaaacaca cattcaggtg aagcagaagt 3700

 atagccataa aacatctaga aagagtgaat gaggctttta gcttttctta 3750

 ggtcaatgtc cagtgtgctt ttttccatgg gaataggata ggtattaata 3800

 cgcttttcta aactgctctc agaccttatc cagaggacat ggtaaagata 3850

 tgttacagaa atttttctga tacttcctgg aataacttta agttacaccc 3900

 tagtagactg gtcattctaa taaaatccag tactataaca aacctctgta 3950

 tgttgatagc acattggccc tttttagagt tctttcctat gtttttctta 4000

 cgtgatttcc cacagttcca tgagtccaac aaaggagagt gataggctcc 4050

 ttatctttta gaagaggaag gaaaggcatg aagaagttga gggactggct 4100

 gaagatcacg tacttactaa gtagtacaac tggagcaaga tcaagtatct 4150

 ctgtctccca tatctgtgtt ctatcattta aaatatatat tggaaatccc 4200

 tgctgactca gattggtatg attaaaaatg agaggaaagt tcaaatagtt 4250

 agtagtgaca aactaatact gctggactaa gattttggta gcattgtttt 4300

 ctaaaatatt ttaaatggag aatgaacact tataaaatgc tttggaacat 4350

 aatctttagc ttaattttct gttaaaattt agtacccctt catcattcca 4400

 ataaagataa gactgatcca ttgtctaagg aaattattta taaataatag 4450

 agattaattt atttgagatt tgaaataaga atagtatgaa aatattagat 4500

 accacataaa ttgtttgaaa ttactgaata accatcttaa gtatggaaca 4550

 tttaaatggc tatattttat ttgtgtacag tttttctgtg ccttgttagg 4600

 ccagtgaagc aattattttc tctaagaaaa tgacaataaa atataacaca 4650

 cttcagattg tctgatttac agtttggaaa ggacaccgca atgttcaaat 4700

 aggtaggaga ccatcaaaaa cacaattaaa gtaacatatt aggagacttg 4750

 aaacttcagc ctaataaatc cttcatggtt cttagcctta ttattgtgat 4800

 ataattctag atattttctt ggagggcatg tgcccaactc tcccgcaccc 4850

 cattttgttt gtcttttaaa gttcttagaa taaacagttc tttatataat 4900

 aattatattt tatttaagaa aatagtttgt taggtacttt ttaaaagatg 4950

 taaattttta aatttacaaa tacatatggg tctttgataa gcaataggaa 5000

 ttgaattaca agttactagg gttataagca aaaggttgct taccataatg 5050

 tcattaggtc acgattttta gctcacatct ggaagcagca actacttggc 5100

 tcaagtacat ataagagtaa ttagttttat tctctctttt ttataaaatc 5150

 gggtttcaga tgagatgttt atcttagact attttaggga aaaattttac 5200

 atgtttgaga tggtggagta aaaagactgt taaacatttc ttttaaaaaa 5250

 ttatttttac attacaacaa tatatttatg atgtgttcag atcaaaaatt 5300

 taacttctgt gtcccagatc tactttcaaa gtgagatttt cacttgtcag 5350

 cttaaatttc tgactagaac taacatttgt gtatttttgt gcttagtcgg 5400

 aatacaaatt tcacagtgga tttttgaagt ttgtccttaa attggataaa 5450

 atcaagtgat taaagttact aaagagataa aaatggtaat ttccattttt 5500

 aaaagtaatt tggttgtgtt tatagttatt tgtacaagta tttatcacag 5550

 actctaaatt gaaaaatgta gtatgatcta tatttgaccc taaaaatgtt 5600

 ggattaattt aacaaatatg gcagattttt cataactaag tcttaagtct 5650

 tctaaaagga agctgttacc cttctgtttt taattacatt aattgaaatg 5700

 tgttttaaga gatacaattt cagcatattt tatatattaa aaaacaaaaa 5750

 aggattagta ttgagccagt ggccaaaagg taatattact accatgtaga 5800

 ctgttatagt tcaaattgtc ccacttcacc cagaatttta gaaactagaa 5850

 gtctgggagg tactatatca gctgtagttg ggtaattcca agtgctgata 5900

 gtactattca tcttttttat tattgtgtca gatgaaacaa atgccaagtt 5950

 gcaaaatatg cagattttta ttatataatg gttttaggca taaattatta 6000

 acaagccatg ccttatgtgt ttcatcttat atttttcttt agaactaaac 6050

 tataacagat tttggaaaat gatttgatgt gcttgctcac ttgattgact 6100

 tggtcagata tttgaatgat ggtattacct agattctaat ccttgattct 6150

 agttatataa taaataatat agaatatgaa aatatgtttg ggcatttact 6200

 gtttatatta tgtagtagcc tccatcatga cacacttact acatttatga 6250

 attgagcagt tctgtaattg taattattat tgctgttcat gtaacaaaac 6300

 atgcttatga taatagcaaa caaatagaaa tgcccccaaa atgctatttt 6350

 tttaattcag ttataactgt tactcttgta gttgtgtatg acgcaataaa 6400

 atttgtaaaa aaatttcagc atgaaaaata aaatttgtat cacctaaaaa 6450

 aaaaaaaaaa a 6461

<210> 3779
<211> 274
<212> PRT
<213> Homo sapien

<400> 3779
 Met Gly Lys Ser Leu Ser His Leu Pro Leu His Ser Ser Lys Glu
   1               5                  10                  15

 Asp Ala Tyr Asp Gly Val Thr Ser Glu Asn Met Arg Asn Gly Leu
                  20                  25                  30

 Val Asn Ser Glu Val His Asn Glu Asp Gly Arg Asn Gly Asp Val
                  35                  40                  45

 Ser Gln Phe Pro Tyr Val Glu Phe Thr Gly Arg Asp Ser Val Thr
                  50                  55                  60

 Cys Pro Thr Cys Gln Gly Thr Gly Arg Ile Pro Arg Gly Gln Glu
                  65                  70                  75

 Asn Gln Leu Val Ala Leu Ile Pro Tyr Ser Asp Gln Arg Leu Arg
                  80                  85                  90

 Pro Arg Arg Thr Lys Leu Tyr Val Met Ala Ser Val Phe Val Cys
                  95                 100                 105

 Leu Leu Leu Ser Gly Leu Ala Val Phe Phe Leu Phe Pro Arg Ser
                 110                 115                 120

 Ile Asp Val Lys Tyr Ile Gly Val Lys Ser Ala Tyr Val Ser Tyr
                 125                 130                 135

 Asp Val Gln Lys Arg Thr Ile Tyr Leu Asn Ile Thr Asn Thr Leu
                 140                 145                 150

 Asn Ile Thr Asn Asn Asn Tyr Tyr Ser Val Glu Val Glu Asn Ile
                 155                 160                 165

 Thr Ala Gln Val Gln Phe Ser Lys Thr Val Ile Gly Lys Ala Arg
                 170                 175                 180

 Leu Asn Asn Ile Thr Ile Ile Gly Pro Leu Asp Met Lys Gln Ile
                 185                 190                 195

 Asp Tyr Thr Val Pro Thr Val Ile Ala Glu Glu Met Ser Tyr Met
                 200                 205                 210

 Tyr Asp Phe Cys Thr Leu Ile Ser Ile Lys Val His Asn Ile Val
                 215                 220                 225

 Leu Met Met Gln Val Thr Val Thr Thr Thr Tyr Phe Gly His Ser
                 230                 235                 240

 Glu Gln Ile Ser Gln Glu Arg Tyr Gln Tyr Val Asp Cys Gly Arg
                 245                 250                 255

 Asn Thr Thr Tyr Gln Leu Gly Gln Ser Glu Tyr Leu Asn Val Leu
                 260                 265                 270

 Gln Pro Gln Gln


<210> 3780
<211> 2026
<212> DNA
<213> Homo sapien

<400> 3780
 attgataata cttttaatgt gttggtaatg atgtttaaaa ttgaaagatt 50

 tttaaaataa aaatgataga ttttcttact aaaaatgttt ttattaacct 100

 tgcttttatt ggaaaaaatc aagcaatatt tctttttctt ttgtgttata 150

 ttgtacttta ctgattcatt tactggtgat acatatgttt ttatggattt 200

 tccagtttaa tttgcatata caaatgaatg caatggtcta ttggtgagca 250

 ttgagcaaca ctgtataaag ttttaaaaat gtaaacactt tttaatctac 300

 tttcctctaa aaatcaataa tattctatta tttctaatcc ttttccactt 350

 gggaaataac aatgaagaat ctgagaattt gacatctata actttacaga 400

 ttcatttttc catttaaatt tcagtttctt ggatcactga atatgggaag 450

 ggagagcttc actaattaga cgcagcttct taagaactta tattctcttt 500

 gacatacatc tctattgtag ttttttgttt tgttttgttt tttgagatgg 550

 agtcttgctc tgtcacccag gctggagtgc agtggtgcaa tctcagctca 600

 ctgcaacctc tgcctcctgg gttcaagtga ttctcgtacc tcagactccc 650

 gagtagttgg gattacaggt gcccaccacc acacccgact aatttttgta 700

 tttttagtag ccatgtggtt ttgccatgtt ggccaggctg gtttcgaact 750

 cctgacctca ggtgatccac ccacctcagc ctcccaaagt gctgggatta 800

 caggtgtgag ccaccgttcc cggcctattg tagattttct taactacttg 850

 ctaaggaaat catatccttt tacatgaact acaggtttag aacttggttt 900

 taagacaact gctatggcca gaaggtaaat gggaattgcc ttattgaagg 950

 taacattgat tgcctaataa gaaaatgaat tgtttgccac agagttgaat 1000

 ttaatttgag ttagatagtt cagaatgtag cacttgccct ataaatgaat 1050

 cagatttgtt ctatttatat aatattagaa ttaatatatt atcatgtaag 1100

 tgggaatttt attttgttaa gtggactctc aaattttaga acttgtgtga 1150

 aatatctccc agaaaacaca aaaggtttca aggtatcacc caaagctagg 1200

 gaatcaacga acgtacttta ttaatgcaag accacaattt aagccccagg 1250

 caggaatcca acagtaacat ttttccttta ggttaagcag taattttttt 1300

 gaattgtcat ttttaatggg tctcacacat gcatattgct aatatcattc 1350

 atgtttgagg ttttcaacaa agaaccaatt tgttaatata atgtacaaaa 1400

 atagttggtt cattttctga attcagtctt tgaaataaaa ctccttgttt 1450

 tggccgtgtt tctgaatgta ttggtgattc acccccaagc taatttttta 1500

 aagtcatttt tgaagttggg aagtctcatg agagatgttg aagtatgtat 1550

 ttaatcaaga gtcatgattt caaactagtt ttacatatta agcagttggt 1600

 gttctaattt aatgggtaaa tgtgtgtttg gataaatatc tgaaaatttt 1650

 atccttaagt atatataatt atttgcctct tatatgtctt aaagctattt 1700

 aaacaaggtg ttaaatgagc caaaacaatt aagtaattag aacagtacat 1750

 ttttatcaga gtgtctgtca tatgcaatga atgtatgtaa tactaaaaaa 1800

 tcatgactac ttttatcaaa gaaaaaccac acattaatcc tattaatcat 1850

 gaaagcgtag cattgtaaat taaaggtttt ctttgaggct cttgaaagtg 1900

 atcccattgc tttcctgttt taaaaatatt ttatgctctt tatttccact 1950

 tctgtgaatg tgatatttct attttgtgat tatgttactg aataaacaaa 2000

 cttgctacat aaaattctta gcaatt 2026

<210> 3781
<211> 5574
<212> DNA
<213> Homo sapien

<400> 3781
 ttttggctgc ctctgtcggt ctgttcagtt accacgtgaa ccgccgacgg 50

 agacccgtag tgggggaggc ggcggcagcg ttaagtgaga aaggaaaaaa 100

 gacaacgagg aaaaaggagg tgtccgggta gggcaacgcg gcgacacccg 150

 aggcctggtg gtggcggcgg atcgagatat tcaaggctga agcagctacg 200

 gaacggcagc ggcggcggtc ggacaaactg actgaccgag ccgggtggtg 250

 gcgggagcag cgggagcagc cggaacgatg ccggccgtga gcctcccgcc 300

 caaggagaat gcgctcttca agcggatctt gaggtgttat gaacataaac 350

 agtatagaaa tggattgaaa ttctgtaaac aaatactttc taatcccaaa 400

 tttgcagagc atggagaaac cttggctatg aaaggattaa cattgaactg 450

 tttggggaaa aaggaagaag cttatgaatt ggttcgtaga ggtttgagaa 500

 atgacttgaa gagtcatgtg tgttggcacg tttatggcct tcttcagagg 550

 tcagacaaga agtatgatga agccattaag tgttacagaa atgcactaaa 600

 atgggataaa gacaatcttc aaatcttaag ggacctttcc ttactacaga 650

 ttcaaatgcg agatcttgag ggttacaggg aaacgaggta tcagttactt 700

 cagcttcgac ctgcgcagag agcatcatgg attggttatg ctattgctta 750

 ccatttatta gaagattatg aaatggcagc aaagatttta gaagaattta 800

 ggaaaacaca acagacatcc cctgacaagg tggattatga atatagtgaa 850

 ctactcttat atcagaatca agttcttcgg gaagcaggtc tctatagaga 900

 agctttggaa catctttgta cctatgaaaa gcagatttgt gataaacttg 950

 ctgtagaaga aaccaaaggg gaacttctgt tgcaactatg tcgtttggaa 1000

 gatgctgcag atgtttatag aggattgcaa gagagaaatc ctgaaaactg 1050

 ggcctattac aaaggcttgg aaaaagcact caagccagct aatatgttag 1100

 aacggctaaa aatttatgag gaagcctgga ctaaatatcc caggggactg 1150

 gtgccaagaa ggctgccgtt aaacttttta tctggtgaga agtttaaaga 1200

 atgtttggat aagttcctaa ggatgaattt cagcaagggt tgcccaccag 1250

 tcttcaatac tttaagatca ttatacaaag acaaagaaaa ggtggcaatc 1300

 atagaagagt tagtagtagg ttatgaaacc tctctaaaaa gctgccggtt 1350

 atttaacccc aatgatgatg gaaaggagga accaccaacc acattacttt 1400

 gggtccagta ctacttggca caacattatg acaaaattgg tcagccatct 1450

 attgctttgg agtacataaa tactgctatt gaaagtacac ctacattaat 1500

 agaactcttt ctcgtgaaag ctaaaatcta taagcatgct ggaaatatta 1550

 aagaagctgc aaggtggatg gatgaggccc aggccttgga cacagcagac 1600

 agatttatca actccaaatg tgcaaaatac atgctaaaag ccaacctgat 1650

 taaagaagct gaagaaatgt gctcaaagtt tacaagggaa ggaacatcag 1700

 cggtagagaa tttgaatgaa atgcagtgca tgtggttcca aacagaatgt 1750

 gcccaggctt ataaagcaat gaataaattt ggtgaagcac ttaagaaatg 1800

 tcatgagatt gagagacatt ttatagaaat cactgatgac cagtttgact 1850

 ttcatacata ctgtatgagg aagattaccc ttagatcata tgtggactta 1900

 ttaaaactag aagatgtact tcgacagcat ccattttact tcaaggcagc 1950

 aagaattgct atagagatct atttgaagct tcatgacaac ccccttacag 2000

 atgagaataa agaacacgaa gctgatacag caaacatgtc tgacaaagag 2050

 ctaaagaagc tacgtaataa acaaagaaga gctcaaaaga aagcccagat 2100

 agaagaagag aaaaaaaatg cagaaaaaga aaagcagcag agaaatcaga 2150

 aaaagaagaa ggatgatgat gatgaggaga taggaggtcc aaaagaagaa 2200

 cttattccag agaaactggc caaggttgaa actccattgg aagaagctat 2250

 taaattttta acaccgttga agaacttggt gaagaacaag atagagactc 2300

 atctttttgc ctttgagatt tactttagga aagaaaagtt tcttttgatg 2350

 ctacaatcag taaagagggc atttgctatt gattctagtc atccctggct 2400

 tcatgagtgt atgattcgtc tctttaatac tgcagtgtgt gaaagtaaag 2450

 atttatctga tacagttaga acagtattaa aacaagaaat gaatcgtctt 2500

 tttggagcaa cgaatccaaa gaattttaat gaaacttttc tgaaaaggaa 2550

 ttctgattca ttgccacaca gattatcagc tgccaaaatg gtatattact 2600

 tagatccttc tagtcagaag cgagctatag agttggcaac aacacttgat 2650

 gaatctctca ctaacagaaa cctccagaca tgtatggagg tattggaagc 2700

 cttgtatgat ggtagcctag gagactgtaa agaagctgct gaaatttata 2750

 gagcaaattg tcataagctt ttcccttatg ctttggcttt catgcctcct 2800

 ggatatgaag aggatatgaa gatcacagtt aatggagata gttctgcaga 2850

 agctgaagaa ctggccaatg aaatttgaac atcactaaac aagcaaatgg 2900

 aatgactttg gaccatatct agtatataat atttttgtca cgcacctgct 2950

 gcattgctct aacttacaca gaatgagagg agtaaatgtt cttgccttca 3000

 aatagtgttt tacgtttttt atcctgctga aaaagtatat ataaaatatc 3050

 taacattaca ggatagaggt tcagtttctt aaaaaattaa agctgctaaa 3100

 attgagtggt taaaaaagat accttatcct attcctcccc acccacccat 3150

 gtttttaaac taatttatat aaaatctgga ggctgttaca gctaacaaag 3200

 caggtgtgtg gcagaaatat tactttaaat ttgtcttgtg agattttact 3250

 atatctcaga cagcataaat gctgttttag cactggattc tttcactgag 3300

 cacaaagagt tgttggggct ttagcatctg actgattttg ttacggggtt 3350

 gattctgacc ataggaagta tgcaatgtga atcactattt acagagaaac 3400

 ctacaacaga tgcttgatgt tgtagaaact gggacatata gataccaagc 3450

 aaaattataa gaaacctata aggtgttcaa tacgcttgtg tttccaaaat 3500

 tcactgtaca tgatcagttt ggtgttcttg taccacagtt tttaactgaa 3550

 ggaaccagtt gtaacagtct caattttaac taaaacttga agaactaaaa 3600

 caacaatgca aacctttcag cattgtttgg ccaaacttgt taaaactgta 3650

 atgcaagaac caaatgcact gtgatgtggc accaactaat tagcaagcat 3700

 gaatttttca cccaagagtg aaaaaaggaa aatctaccat ggcttgaagt 3750

 taaagagcag aactcctgac taccattcta tgactgatca aaagactaat 3800

 agttaaaaac ctcagcaggc cttgttcacg atatgcagaa aaaaaagtgc 3850

 tgcagtttag atacctctgg aatttttcca cagtgtcaca ggtttgtaat 3900

 acttgaagcc ctacatttct aagaatatat ttcttgctca gttgtttcag 3950

 gcaagcccaa gactttgtaa tttttaaagg gcccaagatt tttttttttt 4000

 tttttttttc aaataacaga ccagcttctt tttcttgcag ttacagatgt 4050

 aatttccttt ttgttgtcaa acataaggta ccaaatatga tgcaataaat 4100

 tgttttgaaa aacagttgtg tgaatatttc aactaatctg tgttgggctt 4150

 ctgtgaaata cacaggtgga aacagaggtg caagccagag gcaatgtaat 4200

 atgctgtaag gctagtgcag atgggagctt tttagaaggg gctaagtgct 4250

 ggtgtcaggg aaattccata atgaagtaga atgctgctcc tgcattaaga 4300

 tttcattgag ggcaaggctg gtggcaggta ctatgaatgt aattcataat 4350

 ttaaaaggaa aactaaaaac tattttgatt tgggaaaatg agccttaatt 4400

 tgttaaacct atacactgag aactagcctc aggcttaata ttctcattgc 4450

 atttgcaaga tctgagcaaa taagattaag taaaacaaat caattgtata 4500

 tataattgac ctttttgtgg aacatgtagt ttatagaaag tatactctaa 4550

 agggaatttg ccgaagacct tttactgatt gaacagttgt gctacaatca 4600

 acttttcata gtacatgacc tgcattccac atctcagtct aacagtttag 4650

 tagtgatgta aagagaagta caaaccgaac tccagtgctt tgttatgttt 4700

 tattaactgg ccctgtctca ggaacatctt aacagatggc aaaaaaacaa 4750

 aaactttttt tcaactccta tgagtggcaa ctgaagttct tattgttggg 4800

 aaagaacact agtcctacct ctgccactaa tgaggtgttt ggaggaggta 4850

 ccagccatat aatagggggt gtatgtgtga attttgttta aactctactg 4900

 tatattgaaa tgaaattcat ttatttgtct tgacaatgtt caaatgatgt 4950

 agattgtctt agaatgaata ttcataagta ctcagaactc ttaagatgca 5000

 gatgccaccc gtgaggagct aaattcctaa tgtgtattgt attccaaccc 5050

 aattttactg gaactattga ataaatcttt tattttcttt caggtttact 5100

 tgatagtgga tacattggtg tcagaggacc ttgactgggt tcattttatg 5150

 tccagacatc acccctgaaa cactgtactg tactatcttg ctctgagtag 5200

 tatcaactgg atcgtctcat atttgcctca ttcatcctat taatttcaaa 5250

 tgatactgtg ggggaaaaac agggttagaa aaacaagtgg aaaaaatgga 5300

 gtgatgttgt aatctaaaca agtgccttat gtttattgct aagaactggt 5350

 gttaccaacc cttttgagaa gaaagggtct cttgacctgt attaacatag 5400

 gaaagtaaag ttctttttgt ttttctttat aagctactct tgtcatttct 5450

 cgttgaaaaa ctaaaatctg actaggttag tttactcagc tttaattaga 5500

 tagttgagtc atatattttc aacatttttc tgtatcgtat ttattatgca 5550

 caaaaataaa gtgtgatctc taat 5574

<210> 3782
<211> 866
<212> PRT
<213> Homo sapien

<400> 3782
 Met Pro Ala Val Ser Leu Pro Pro Lys Glu Asn Ala Leu Phe Lys
   1               5                  10                  15

 Arg Ile Leu Arg Cys Tyr Glu His Lys Gln Tyr Arg Asn Gly Leu
                  20                  25                  30

 Lys Phe Cys Lys Gln Ile Leu Ser Asn Pro Lys Phe Ala Glu His
                  35                  40                  45

 Gly Glu Thr Leu Ala Met Lys Gly Leu Thr Leu Asn Cys Leu Gly
                  50                  55                  60

 Lys Lys Glu Glu Ala Tyr Glu Leu Val Arg Arg Gly Leu Arg Asn
                  65                  70                  75

 Asp Leu Lys Ser His Val Cys Trp His Val Tyr Gly Leu Leu Gln
                  80                  85                  90

 Arg Ser Asp Lys Lys Tyr Asp Glu Ala Ile Lys Cys Tyr Arg Asn
                  95                 100                 105

 Ala Leu Lys Trp Asp Lys Asp Asn Leu Gln Ile Leu Arg Asp Leu
                 110                 115                 120

 Ser Leu Leu Gln Ile Gln Met Arg Asp Leu Glu Gly Tyr Arg Glu
                 125                 130                 135

 Thr Arg Tyr Gln Leu Leu Gln Leu Arg Pro Ala Gln Arg Ala Ser
                 140                 145                 150

 Trp Ile Gly Tyr Ala Ile Ala Tyr His Leu Leu Glu Asp Tyr Glu
                 155                 160                 165

 Met Ala Ala Lys Ile Leu Glu Glu Phe Arg Lys Thr Gln Gln Thr
                 170                 175                 180

 Ser Pro Asp Lys Val Asp Tyr Glu Tyr Ser Glu Leu Leu Leu Tyr
                 185                 190                 195

 Gln Asn Gln Val Leu Arg Glu Ala Gly Leu Tyr Arg Glu Ala Leu
                 200                 205                 210

 Glu His Leu Cys Thr Tyr Glu Lys Gln Ile Cys Asp Lys Leu Ala
                 215                 220                 225

 Val Glu Glu Thr Lys Gly Glu Leu Leu Leu Gln Leu Cys Arg Leu
                 230                 235                 240

 Glu Asp Ala Ala Asp Val Tyr Arg Gly Leu Gln Glu Arg Asn Pro
                 245                 250                 255

 Glu Asn Trp Ala Tyr Tyr Lys Gly Leu Glu Lys Ala Leu Lys Pro
                 260                 265                 270

 Ala Asn Met Leu Glu Arg Leu Lys Ile Tyr Glu Glu Ala Trp Thr
                 275                 280                 285

 Lys Tyr Pro Arg Gly Leu Val Pro Arg Arg Leu Pro Leu Asn Phe
                 290                 295                 300

 Leu Ser Gly Glu Lys Phe Lys Glu Cys Leu Asp Lys Phe Leu Arg
                 305                 310                 315

 Met Asn Phe Ser Lys Gly Cys Pro Pro Val Phe Asn Thr Leu Arg
                 320                 325                 330

 Ser Leu Tyr Lys Asp Lys Glu Lys Val Ala Ile Ile Glu Glu Leu
                 335                 340                 345

 Val Val Gly Tyr Glu Thr Ser Leu Lys Ser Cys Arg Leu Phe Asn
                 350                 355                 360

 Pro Asn Asp Asp Gly Lys Glu Glu Pro Pro Thr Thr Leu Leu Trp
                 365                 370                 375

 Val Gln Tyr Tyr Leu Ala Gln His Tyr Asp Lys Ile Gly Gln Pro
                 380                 385                 390

 Ser Ile Ala Leu Glu Tyr Ile Asn Thr Ala Ile Glu Ser Thr Pro
                 395                 400                 405

 Thr Leu Ile Glu Leu Phe Leu Val Lys Ala Lys Ile Tyr Lys His
                 410                 415                 420

 Ala Gly Asn Ile Lys Glu Ala Ala Arg Trp Met Asp Glu Ala Gln
                 425                 430                 435

 Ala Leu Asp Thr Ala Asp Arg Phe Ile Asn Ser Lys Cys Ala Lys
                 440                 445                 450

 Tyr Met Leu Lys Ala Asn Leu Ile Lys Glu Ala Glu Glu Met Cys
                 455                 460                 465

 Ser Lys Phe Thr Arg Glu Gly Thr Ser Ala Val Glu Asn Leu Asn
                 470                 475                 480

 Glu Met Gln Cys Met Trp Phe Gln Thr Glu Cys Ala Gln Ala Tyr
                 485                 490                 495

 Lys Ala Met Asn Lys Phe Gly Glu Ala Leu Lys Lys Cys His Glu
                 500                 505                 510

 Ile Glu Arg His Phe Ile Glu Ile Thr Asp Asp Gln Phe Asp Phe
                 515                 520                 525

 His Thr Tyr Cys Met Arg Lys Ile Thr Leu Arg Ser Tyr Val Asp
                 530                 535                 540

 Leu Leu Lys Leu Glu Asp Val Leu Arg Gln His Pro Phe Tyr Phe
                 545                 550                 555

 Lys Ala Ala Arg Ile Ala Ile Glu Ile Tyr Leu Lys Leu His Asp
                 560                 565                 570

 Asn Pro Leu Thr Asp Glu Asn Lys Glu His Glu Ala Asp Thr Ala
                 575                 580                 585

 Asn Met Ser Asp Lys Glu Leu Lys Lys Leu Arg Asn Lys Gln Arg
                 590                 595                 600

 Arg Ala Gln Lys Lys Ala Gln Ile Glu Glu Glu Lys Lys Asn Ala
                 605                 610                 615

 Glu Lys Glu Lys Gln Gln Arg Asn Gln Lys Lys Lys Lys Asp Asp
                 620                 625                 630

 Asp Asp Glu Glu Ile Gly Gly Pro Lys Glu Glu Leu Ile Pro Glu
                 635                 640                 645

 Lys Leu Ala Lys Val Glu Thr Pro Leu Glu Glu Ala Ile Lys Phe
                 650                 655                 660

 Leu Thr Pro Leu Lys Asn Leu Val Lys Asn Lys Ile Glu Thr His
                 665                 670                 675

 Leu Phe Ala Phe Glu Ile Tyr Phe Arg Lys Glu Lys Phe Leu Leu
                 680                 685                 690

 Met Leu Gln Ser Val Lys Arg Ala Phe Ala Ile Asp Ser Ser His
                 695                 700                 705

 Pro Trp Leu His Glu Cys Met Ile Arg Leu Phe Asn Thr Ala Val
                 710                 715                 720

 Cys Glu Ser Lys Asp Leu Ser Asp Thr Val Arg Thr Val Leu Lys
                 725                 730                 735

 Gln Glu Met Asn Arg Leu Phe Gly Ala Thr Asn Pro Lys Asn Phe
                 740                 745                 750

 Asn Glu Thr Phe Leu Lys Arg Asn Ser Asp Ser Leu Pro His Arg
                 755                 760                 765

 Leu Ser Ala Ala Lys Met Val Tyr Tyr Leu Asp Pro Ser Ser Gln
                 770                 775                 780

 Lys Arg Ala Ile Glu Leu Ala Thr Thr Leu Asp Glu Ser Leu Thr
                 785                 790                 795

 Asn Arg Asn Leu Gln Thr Cys Met Glu Val Leu Glu Ala Leu Tyr
                 800                 805                 810

 Asp Gly Ser Leu Gly Asp Cys Lys Glu Ala Ala Glu Ile Tyr Arg
                 815                 820                 825

 Ala Asn Cys His Lys Leu Phe Pro Tyr Ala Leu Ala Phe Met Pro
                 830                 835                 840

 Pro Gly Tyr Glu Glu Asp Met Lys Ile Thr Val Asn Gly Asp Ser
                 845                 850                 855

 Ser Ala Glu Ala Glu Glu Leu Ala Asn Glu Ile
                 860                 865

<210> 3783
<211> 1669
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 446
<223> Unknown base

<400> 3783
 ctgtcatggc ggcggccgcc cccaatgccg gaggctcggc ccctgagaca 50

 gcgggttccg ccgaagctcc gctgcagtac agcctgctcc tgcagtacct 100

 ggtgggtgac aagcgtcagc cccggctcct ggagcctggg agcctgggcg 150

 ggatcccaag tccagccaag agtgaggagc agaagatgat cgagaaggcg 200

 atggaaagct gcgctttcaa ggctgcgctg gcctgcgtgg gaggatttgt 250

 cttaggaggt gcatttgggg tgtttaccgc tggcatcgat accaacgtgg 300

 gctttgaccc taaggatcct taccgtacac cgactgcaaa agaagtgctg 350

 aaagaacatg ggcagagagg aatgtcctat gccaaaaatt tcgccattgt 400

 gggagccatg ttttcttgta cctggtgttt gatagaatct taccgnggaa 450

 catcagactt gaagaacagt gtcatcagtg gctgcatcac gggaggagcc 500

 tattggttca gagctggctt aaaggctggg gcccttttgt gtggaggttt 550

 tgctgctttc tctgctgcga ttgattatta cctccggtga gagtaattgc 600

 ctgcagggaa ggatgatgcc agccccggat ccgggctgct ctctggagga 650

 cagtttctgt accacaccag ggccttgctt cagggcctga agacattcat 700

 tttccctcat gtcgttggta ttctgaggga gctgcctggc ttctctgcct 750

 ccagcctttg gggtagccac actttgctgc tcctggactc cagccagcct 800

 tcacagagga cgtcccgtgc cagattctct cacagcagat cgggagacag 850

 gatgttgaca tataggaatt cagctccaca aagcttcagg cctgaccaca 900

 gctggccctc taggttgttt ggtgttgtgg gcacagaggt gacagtgtct 950

 ctgcaggcac tcaggaagct gttctacctt ggaactccat gcaactatcc 1000

 gtctcgaata ccagggcagg gcaaggcgga ctgatgccgt ccaaccaatt 1050

 atctcacttg ttttgtgttc tgtcatcctt gttttttttt taaaaataca 1100

 ctcccctccc ccaccgccac acaccttaca gttcaaaagg ttggtttatt 1150

 tgtattttat tttcaaattc cctattccaa aaatagtgcc gggtggccca 1200

 aagataacat ctgaagggaa agaatgagaa agctcccagg gaagyggggg 1250

 atggggcgct gaggcagggt tgttagagga ctgtgtcatc ctcaccaagc 1300

 tcattacatc tgccagggcc tgcctcaaga agcccagccc agccttttcc 1350

 tgggatgcag tgaaatccca tccatgaact cgatgggccc ctcctgtgcc 1400

 ggccgagagg cacacactgc cttcacgacg tgactgctgg acctggccga 1450

 gcttgaggcc acatgtgaag ggtcctgctg tggtcatctt ggtgactcgg 1500

 tcacagcagc tactggccaa gatcagacgt cgctgagggg ctgttcacca 1550

 ccatcctcgt tctccagggt caaggaagtg ttttaacatg tcgtgttttc 1600

 gacttgacct tgtggtattt ttcttggcct agttgtgtgc catggatatt 1650

 taaaaaaaaa aaaaaaaaa 1669

<210> 3784
<211> 194
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 446
<223> Unknown amino acid

<400> 3784
 Met Ala Ala Ala Ala Pro Asn Ala Gly Gly Ser Ala Pro Glu Thr
   1               5                  10                  15

 Ala Gly Ser Ala Glu Ala Pro Leu Gln Tyr Ser Leu Leu Leu Gln
                  20                  25                  30

 Tyr Leu Val Gly Asp Lys Arg Gln Pro Arg Leu Leu Glu Pro Gly
                  35                  40                  45

 Ser Leu Gly Gly Ile Pro Ser Pro Ala Lys Ser Glu Glu Gln Lys
                  50                  55                  60

 Met Ile Glu Lys Ala Met Glu Ser Cys Ala Phe Lys Ala Ala Leu
                  65                  70                  75

 Ala Cys Val Gly Gly Phe Val Leu Gly Gly Ala Phe Gly Val Phe
                  80                  85                  90

 Thr Ala Gly Ile Asp Thr Asn Val Gly Phe Asp Pro Lys Asp Pro
                  95                 100                 105

 Tyr Arg Thr Pro Thr Ala Lys Glu Val Leu Lys Glu His Gly Gln
                 110                 115                 120

 Arg Gly Met Ser Tyr Ala Lys Asn Phe Ala Ile Val Gly Ala Met
                 125                 130                 135

 Phe Ser Cys Thr Trp Cys Leu Ile Glu Ser Tyr Arg Gly Thr Ser
                 140                 145                 150

 Asp Leu Lys Asn Ser Val Ile Ser Gly Cys Ile Thr Gly Gly Ala
                 155                 160                 165

 Tyr Trp Phe Arg Ala Gly Leu Lys Ala Gly Ala Leu Leu Cys Gly
                 170                 175                 180

 Gly Phe Ala Ala Phe Ser Ala Ala Ile Asp Tyr Tyr Leu Arg
                 185                 190

<210> 3785
<211> 3076
<212> DNA
<213> Homo sapien

<400> 3785
 cgggtggatt acctgagaac ctctaaaatg cagacctcca gctctagatc 50

 tgtgcacctg agtgaatggc agaagaatta cttcgcaatt acatctggca 100

 tatgtaccgg accgaagcag atgcataccg tgcacagata ttacgcattc 150

 agtatgcatg ggcaaactct gagatttccc aggatctcaa caaacagata 200

 gtgacaagtg gcagtctgga ttgtcaataa ataatgtttt caaaatgagt 250

 agtgtacaga agatgatgca agctggcaaa aaattcaaag actctctgtt 300

 ggaacctgct cttgcatcag tggtaatcca taaggaggcc actgtctttg 350

 atcttcctaa atttagtgtt tgtggtagtt ctcaagagag tgactcatta 400

 cctaactcag ctcatgatcg agaccggacc caagacttcc cggagagcaa 450

 tcgtttgaaa ctccttcaga atgcccagcc acctatggtg actaacactg 500

 ctaggacttg tcctacattc tcagcacctg taggtgagtc agctactgca 550

 aaattccatg tcacaccatt gtttggaaat gtcaaaaagg aaaatcacag 600

 ctctgcaaaa gaaaacatag gacttaatgt gttcttatct aaccagtctt 650

 gttttcctgc tgcctgtgaa aatccacaga ggaagtcttt ttatggttct 700

 ggcaccattg atgcactttc caatccaata ctgaataagg cttgtagtaa 750

 aacagaagat aatggcccaa aggaggatag cagcctgcct acatttaaaa 800

 ctgcaaaaga acaattatgg gtagatcagc aaaaaaagta ccaccaacct 850

 cagcgtgcat cagggtcttc atatggtggt gtaaaaaagt ctctaggagc 900

 tagtagatcc cgagggatac ttggaaagtt tgttcctcct atacccaagc 950

 aagatggggg agagcagaat ggaggaatgc aatgtaagcc ttatggggca 1000

 ggacctacag aaccagcaca tccagttgat gagcgtctga agaacttgga 1050

 gccaaagatg attgaactta ttatgaatga gattatggat catggacctc 1100

 cagtaaattg ggaagatatt gcaggagtag aatttgctaa agccaccata 1150

 aaggaaatag ttgtgtggcc catgttgagg ccagacatct ttactggttt 1200

 aaggggaccc cctaaaggaa ttttgctctt tggtcctcct gggactggta 1250

 aaactctaat tggcaagtgc attgctagtc agtctggggc aacattcttt 1300

 agcatctctg cttcatcctt aacttctaaa tgggtaggtg agggggagaa 1350

 aatggtccgt gcattgtttg ctgttgcaag gtgtcagcaa ccagctgtga 1400

 tatttattga cgaaattgat tccttgttat ctcaacgggg agatggtgag 1450

 catgaatctt ctagaaggat aaaaacagaa tttttagttc aattagatgg 1500

 agcaacaaca tcttctgaag atcgtatcct agtggtggga gcaacaaatc 1550

 ggccacaaga aattgatgag gctgcccgga gaagattggt gaaaaggctt 1600

 tatattcccc tcccagaagc ttcagccagg aaacagatag taattaatct 1650

 aatgtccaaa gagcagtgtt gcctcagtga agaagaaatt gaacagattg 1700

 tacagcagtc tgatgcgttt tcaggagcag acatgacaca gctttgcagg 1750

 gaggcttctc ttggtcctat tcgcagttta caaactgctg acattgctac 1800

 cataacaccg gatcaagttc gacccatagc ttacattgat tttgaaaatg 1850

 cttttagaac tgtgcgacct agtgtttctc caaaagattt agagctttat 1900

 gaaaactgga acaaaacttt tggttgtgga aagtaagtgg gatacttgga 1950

 atcaaggcat ctctgtatta cagtcttctt tattttttag catagaaagt 2000

 tggggatgtg ttaattgtat ttttaagaat atattctaaa ttctgtactt 2050

 caaataatag cacagatttt acatctgatt gacatagtgt atgttaatgt 2100

 aagttttgct ttccagtgat tacctgatac gtaagcctat ttgaacaaag 2150

 tgagaatgaa cttttgtttc taagaagtct ttatcttgaa gctatataac 2200

 atgaaaagtg agctcaaatt ttttttagtt gaagattaca tataaagttg 2250

 tgtctgatta atattcatct tttattgaag aaagtgcctt ctgatggcca 2300

 cataattctt aatgtcagct agtataatgg tttacatttg gacaaagtat 2350

 tgcttagtgt tatttaagta gatttaagat ctcaaagcta aagtgccaat 2400

 ttttactttc ttcagccaat ttgttacctc ttttatggtt tttaattttt 2450

 atcaggacta acattttcag aaatagcaag gtgtgatcta gtattagatt 2500

 cacagaactg aaaggttaat taagaatgtt ggttattttc acgggagcgt 2550

 gtgatattta acattaatat tttatttgac actacagcct gtaatactgc 2600

 tctctttcaa aagcaagttt tcagattttt ataacagacc cattttgttt 2650

 tatgaaacat gttcattaca gaaacatgag aaaatagaga taagtaaaaa 2700

 gaataaaagt cactattatc ctaccacttt gcgggacaca ctattaatat 2750

 ttaagcatag attcttccag atgttttgtt ttatacagca gtaggattgt 2800

 gtaatgtatt ctctcttgta gcctattctt caaagcgtat cttcactttc 2850

 catgttaaca taaatgtcct tttatgattg tctaggattc catggatgga 2900

 tggaatataa ttgagtcatc tggtagagcg catataggac aggacgctag 2950

 gttgtttatc ttttgtttat tgtaaaggaa ctatgtggga tgcatttggt 3000

 gatcttttta aaaaatgtat aaatttcttg agtaattcct ggattaaaga 3050

 atatgcactt tttaaaaaaa aaaaaa 3076

<210> 3786
<211> 563
<212> PRT
<213> Homo sapien

<400> 3786
 Met Ser Ser Val Gln Lys Met Met Gln Ala Gly Lys Lys Phe Lys
   1               5                  10                  15

 Asp Ser Leu Leu Glu Pro Ala Leu Ala Ser Val Val Ile His Lys
                  20                  25                  30

 Glu Ala Thr Val Phe Asp Leu Pro Lys Phe Ser Val Cys Gly Ser
                  35                  40                  45

 Ser Gln Glu Ser Asp Ser Leu Pro Asn Ser Ala His Asp Arg Asp
                  50                  55                  60

 Arg Thr Gln Asp Phe Pro Glu Ser Asn Arg Leu Lys Leu Leu Gln
                  65                  70                  75

 Asn Ala Gln Pro Pro Met Val Thr Asn Thr Ala Arg Thr Cys Pro
                  80                  85                  90

 Thr Phe Ser Ala Pro Val Gly Glu Ser Ala Thr Ala Lys Phe His
                  95                 100                 105

 Val Thr Pro Leu Phe Gly Asn Val Lys Lys Glu Asn His Ser Ser
                 110                 115                 120

 Ala Lys Glu Asn Ile Gly Leu Asn Val Phe Leu Ser Asn Gln Ser
                 125                 130                 135

 Cys Phe Pro Ala Ala Cys Glu Asn Pro Gln Arg Lys Ser Phe Tyr
                 140                 145                 150

 Gly Ser Gly Thr Ile Asp Ala Leu Ser Asn Pro Ile Leu Asn Lys
                 155                 160                 165

 Ala Cys Ser Lys Thr Glu Asp Asn Gly Pro Lys Glu Asp Ser Ser
                 170                 175                 180

 Leu Pro Thr Phe Lys Thr Ala Lys Glu Gln Leu Trp Val Asp Gln
                 185                 190                 195

 Gln Lys Lys Tyr His Gln Pro Gln Arg Ala Ser Gly Ser Ser Tyr
                 200                 205                 210

 Gly Gly Val Lys Lys Ser Leu Gly Ala Ser Arg Ser Arg Gly Ile
                 215                 220                 225

 Leu Gly Lys Phe Val Pro Pro Ile Pro Lys Gln Asp Gly Gly Glu
                 230                 235                 240

 Gln Asn Gly Gly Met Gln Cys Lys Pro Tyr Gly Ala Gly Pro Thr
                 245                 250                 255

 Glu Pro Ala His Pro Val Asp Glu Arg Leu Lys Asn Leu Glu Pro
                 260                 265                 270

 Lys Met Ile Glu Leu Ile Met Asn Glu Ile Met Asp His Gly Pro
                 275                 280                 285

 Pro Val Asn Trp Glu Asp Ile Ala Gly Val Glu Phe Ala Lys Ala
                 290                 295                 300

 Thr Ile Lys Glu Ile Val Val Trp Pro Met Leu Arg Pro Asp Ile
                 305                 310                 315

 Phe Thr Gly Leu Arg Gly Pro Pro Lys Gly Ile Leu Leu Phe Gly
                 320                 325                 330

 Pro Pro Gly Thr Gly Lys Thr Leu Ile Gly Lys Cys Ile Ala Ser
                 335                 340                 345

 Gln Ser Gly Ala Thr Phe Phe Ser Ile Ser Ala Ser Ser Leu Thr
                 350                 355                 360

 Ser Lys Trp Val Gly Glu Gly Glu Lys Met Val Arg Ala Leu Phe
                 365                 370                 375

 Ala Val Ala Arg Cys Gln Gln Pro Ala Val Ile Phe Ile Asp Glu
                 380                 385                 390

 Ile Asp Ser Leu Leu Ser Gln Arg Gly Asp Gly Glu His Glu Ser
                 395                 400                 405

 Ser Arg Arg Ile Lys Thr Glu Phe Leu Val Gln Leu Asp Gly Ala
                 410                 415                 420

 Thr Thr Ser Ser Glu Asp Arg Ile Leu Val Val Gly Ala Thr Asn
                 425                 430                 435

 Arg Pro Gln Glu Ile Asp Glu Ala Ala Arg Arg Arg Leu Val Lys
                 440                 445                 450

 Arg Leu Tyr Ile Pro Leu Pro Glu Ala Ser Ala Arg Lys Gln Ile
                 455                 460                 465

 Val Ile Asn Leu Met Ser Lys Glu Gln Cys Cys Leu Ser Glu Glu
                 470                 475                 480

 Glu Ile Glu Gln Ile Val Gln Gln Ser Asp Ala Phe Ser Gly Ala
                 485                 490                 495

 Asp Met Thr Gln Leu Cys Arg Glu Ala Ser Leu Gly Pro Ile Arg
                 500                 505                 510

 Ser Leu Gln Thr Ala Asp Ile Ala Thr Ile Thr Pro Asp Gln Val
                 515                 520                 525

 Arg Pro Ile Ala Tyr Ile Asp Phe Glu Asn Ala Phe Arg Thr Val
                 530                 535                 540

 Arg Pro Ser Val Ser Pro Lys Asp Leu Glu Leu Tyr Glu Asn Trp
                 545                 550                 555

 Asn Lys Thr Phe Gly Cys Gly Lys
                 560

<210> 3787
<211> 4877
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4105-4123, 4128
<223> Unknown base

<400> 3787
 attggcgggc acgccccctc gcccgcggcc ccctccccgc ctctctccac 50

 cgcctcctct ggctccccgg tcagagggcc ggagcgagaa gatggcgaag 100

 acgtacgatt atctcttcaa gctcctgctg atcggcgact cgggggtagg 150

 caagacctgc ctcctgttcc gcttctcaga ggacgccttc aacaccacct 200

 tcatctccac catcggaatt gattttaaaa ttagaacgat agaactagat 250

 ggaaagaaaa ttaagcttca gatatgggac acagcgggtc aggaaagatt 300

 ccgaacaatc acgacagcgt actacagagg agccatgggc attatgctgg 350

 tctatgacat cacaaatgaa aaatcctttg acaatattaa aaattggatc 400

 agaaacattg aagagcatgc ctcttccgat gtcgaaagaa tgatcctggg 450

 taacaaatgt gatatgaatg acaaaagaca agtgtcaaaa gaaagagggg 500

 agaagctagc aattgactat gggattaaat tcttggagac aagcgcaaaa 550

 tccagtgcaa atgtagaaga ggcatttttt acacttgcac gagatataat 600

 gacaaaactc aacagaaaaa tgaatgacag caattcagca ggagcaggtg 650

 gaccagtgaa aataacagaa aaccgatcaa agaagaccag tttctttcgt 700

 tgctcgctac tttgatgaac tctttctgag agactgcagc acacctagag 750

 ggccctttcc tgcttctctg aaagcacagg tcacccagcc tcagaatcac 800

 acctcccggc tgctgctgag agcaccactg aacttagacc tctcaacaca 850

 gtatgccaag tggattccag cctcatggcc tagcaaaaga acagactccc 900

 tttttcaaac atggaagcaa tgaagtggag acacatgcag gacctaactc 950

 gttttttcct tgttttatta cctgttgcag aagcggttat ctttcttttt 1000

 tactttgcac atcagtgtta gcctttccct atttcagcac aatcttagac 1050

 tcatatttgc acacttttgt gtcgtgaagt tctagacaaa tttgtacatg 1100

 tggcaatgtt aaaagagcat ttacagcaga ggttaatata ctaaaattaa 1150

 agggtatttg gtctggttca tatggtcaaa tattactgcc ttggtagcat 1200

 ttatttaagg gctttttctt aaataagaat cattaaagtc attaaaaaaa 1250

 tttactgaaa tgcccatctt gtcatcaaag gccacaattt ctttatttct 1300

 tcagattaag agctttgcct catccccgac ctgttttcca gagtctgggt 1350

 agctgaatga atcactttaa aatgattacc tctgcctaat ctatagaaac 1400

 tgcatttgga aatcaccata atctcatttt tccctggggt ttgtatttgc 1450

 tattctttcc catgtttgac ttaagtgtaa tcactcttaa gtaatatttg 1500

 aacattatta tctgtttcta tttgtgaact tcttgagctg aaattttacg 1550

 tgggctgaga gatataccat ttagggtttt agtgcagcat ctaactgtga 1600

 ttctgtcaat aaggatatgt aatatatttt ttcttaggtt cactccttag 1650

 ctggctggtt tagttgtaat accaaattcc taccataatc cctgtctaca 1700

 aaagttaggt ttagatttta gtttgcggaa accttcccta tatagagaca 1750

 gattaacttg ttgatataaa tttaatagag ctagctcttg gtaatggtga 1800

 aaataatgag ttttggttgg ttttatttgg cagatgtttt tagaaataaa 1850

 agtacttaga cctagtgcag cctctaggaa aagtcttgcc ttttcattag 1900

 agaaaacagg accaaggttt cagttttcaa acagctgttg ttgaatgtgt 1950

 agaacccagt tccatctgtt ttggttcatt gttacagaac ttagtccagt 2000

 catttgggct aaagccaacc aaaagcttag ttgcctttct caacaaacac 2050

 tggtactggt atacttttgt agatgaaacc atcacaaggt atttagtgtt 2100

 aacttgtgtg ccaaattcag atcactatgt cgttgttgct ctagccttca 2150

 gtgtcataac acagggggga taaaacagag gggatgaggg aaatgaattc 2200

 tgttaataat tattcttcct ggtatgcctg ttttgcttca caaaggctac 2250

 tatcatgctg gatagataag aacaggagat ggcagtggaa agggattgct 2300

 tgttaccaca gagaattctc ttcaaattaa gatatgtcat tagaatgctt 2350

 ggaccagtca atcttttgta cttatttgaa aatataggaa caatttagca 2400

 gctgcaaata tgcccaagct atttttaata gatatactaa acttattgtt 2450

 gacaaatttc agcctcctta attttttttt tttttggtaa ttacctatag 2500

 gcttaaaagt cattcgttgc tgttctagta taattagtag ttccgtgatt 2550

 gaaagtttat ggtaattcta ctatcttcaa attagataca ttttcaaaag 2600

 gaaaagataa ttttttagaa acatcttaat attcactatt tcctgaaaaa 2650

 atccaagcag ttaacgcttt ctggatggta acaaagtacc ttctaaaaga 2700

 taagtgctat gacaccatgt atgaatgtaa ttctcttagt aatttacctc 2750

 tgactatttg gtgtcttaac gctttggttt atataatctc aggggttgtc 2800

 tgcaaaccaa aactgacata ttctgtggtt agcttttatt actttttttt 2850

 ttaacagaat gctttgcttt ggttatattt cttctttctt cttttgtctt 2900

 atatggatta ataactagtc tccatgaact tcacttgaaa gagcctgtaa 2950

 aagttagatg agtctaaaag tgctctttga agtagcagca aattgggagt 3000

 atatgctctg ttatatagaa ataaattgtc cttgctattt tcttacattt 3050

 agctttgcta gattgtatat acattgagct aagaccttag gaaattcact 3100

 ttctgcatga taaaatgacc caataaatat tccactttgc ttaataatgt 3150

 acatacagtg cattattttt tctatttgta gatgaattta atgacagata 3200

 attgtctgtt ccccgctgaa actgaagaaa tctagttttt ttgtgaacat 3250

 ttttgtggtc ttatggataa ggtacatgaa gatttttgca gcagtattag 3300

 tggttcagtg gctgcacttt attaatcagt gtgttaattt ttgacagtga 3350

 ttggactaga ccttttcaaa tagagtctga gggtatcaga cagtgaaaat 3400

 gtgctgtaac taagtagcat gtaaatcagt tgattgtaaa acgtttcgct 3450

 gggaacttat tttagctata ttttacttca gacagattat gatacaataa 3500

 tctacctgtg catcagttag taggtgctgc agggtttctt actatttaca 3550

 gaaacatttt gtgcagtctt tgttataaat tttcagaaga ctatactctt 3600

 tactttgaag gtctattttt taattatacc tcatttagct aactagtatt 3650

 ctaatacctg gtagaaaaac agtgagccag cctttaagca tctaacaaaa 3700

 tttagactct ttgttttgtt ttgaactgaa gacatcattg ggaaaggtag 3750

 gaaatattag tttaggatag agcatacatg tcatatccag tagcataaaa 3800

 aaagtattat ctccctgtct ccattaataa atttagctgt gcaatatagg 3850

 tgcgtttttg cagaagtttc tagtaagaga ttataactcc attttacagg 3900

 ttctgaatgc tcagagtcta tattaaggct tataaagttt ttcctgtgat 3950

 cagtaagtga cacatttaag cagacattct tttcaagttc atgacttaga 4000

 ttcctttaca aatttagttc tcaatcttta aaaaccacat ttcattatgt 4050

 tggttaatta ttataaattt taagcactca tttctgcaat caggtttctc 4100

 agaannnnnn nnnnnnnnnn nnnggggnca ttcctttttc cttgttacat 4150

 ccaagggggg cacaggggtg ggtggaaagg aatgtctaaa aatgaaatcc 4200

 cttgatatag agggacctag acggacagga tatgctaaaa taatttcaaa 4250

 ttctagcaca attttagagt agaataagtc atttttttag actaataaaa 4300

 ttaatggctg tcatgttcac tctgaaaaaa atctaaatga ctgaaatgta 4350

 cagaaataaa aattagcaaa caattattct agggatattt tcagatttta 4400

 cttcatttct tgaaatgcgt gtgccatatg caattgcatt tcttgtgcca 4450

 agaaactaat agaacttatt tcactttacc tttttttaaa atgtgaattt 4500

 agttattata gttcaatttt atggccttac agatggcttt tattttgttt 4550

 gcagctgaca ctgcagttcc tttcatgcaa aataccataa actgtttgat 4600

 gaaaatcatg cccctaatgg aaactctcta gtttttccat ataactatcc 4650

 tactgtacat gtttaaacat attttatttt tgctccaatg gcttaatgtg 4700

 aaaagctcct gcagataagt ggacctgtca tgtggttaat cttgtttaag 4750

 ccaattcatt aactgtgtac tgatactgat gctatgtttt ttttaaatgg 4800

 attttattcc aggtgaactt tttttttata ataatgttcg tctaaaataa 4850

 aaactacata atgaaaatga aaatgct 4877

<210> 3788
<211> 237
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4105-4123, 4128
<223> Unknown amino acid

<400> 3788
 Leu Ala Gly Thr Pro Pro Arg Pro Arg Pro Pro Pro Arg Leu Ser
   1               5                  10                  15

 Pro Pro Pro Pro Leu Ala Pro Arg Ser Glu Gly Arg Ser Glu Lys
                  20                  25                  30

 Met Ala Lys Thr Tyr Asp Tyr Leu Phe Lys Leu Leu Leu Ile Gly
                  35                  40                  45

 Asp Ser Gly Val Gly Lys Thr Cys Leu Leu Phe Arg Phe Ser Glu
                  50                  55                  60

 Asp Ala Phe Asn Thr Thr Phe Ile Ser Thr Ile Gly Ile Asp Phe
                  65                  70                  75

 Lys Ile Arg Thr Ile Glu Leu Asp Gly Lys Lys Ile Lys Leu Gln
                  80                  85                  90

 Ile Trp Asp Thr Ala Gly Gln Glu Arg Phe Arg Thr Ile Thr Thr
                  95                 100                 105

 Ala Tyr Tyr Arg Gly Ala Met Gly Ile Met Leu Val Tyr Asp Ile
                 110                 115                 120

 Thr Asn Glu Lys Ser Phe Asp Asn Ile Lys Asn Trp Ile Arg Asn
                 125                 130                 135

 Ile Glu Glu His Ala Ser Ser Asp Val Glu Arg Met Ile Leu Gly
                 140                 145                 150

 Asn Lys Cys Asp Met Asn Asp Lys Arg Gln Val Ser Lys Glu Arg
                 155                 160                 165

 Gly Glu Lys Leu Ala Ile Asp Tyr Gly Ile Lys Phe Leu Glu Thr
                 170                 175                 180

 Ser Ala Lys Ser Ser Ala Asn Val Glu Glu Ala Phe Phe Thr Leu
                 185                 190                 195

 Ala Arg Asp Ile Met Thr Lys Leu Asn Arg Lys Met Asn Asp Ser
                 200                 205                 210

 Asn Ser Ala Gly Ala Gly Gly Pro Val Lys Ile Thr Glu Asn Arg
                 215                 220                 225

 Ser Lys Lys Thr Ser Phe Phe Arg Cys Ser Leu Leu
                 230                 235

<210> 3789
<211> 1707
<212> DNA
<213> Homo sapien

<400> 3789
 ggcacgagga ggcgccctcc gactccttgc gccgcactgc tcgccgggcc 50

 agtccggaaa cgggtcgtgg agctccgcac cactcccgct ggttcccgaa 100

 ggcagatccc ttctcccgag agttgcgaga aactttccct tgtccccgac 150

 gctgcagcgg ctcgggtacc gtggcagccg caggtttctg aaccccgggc 200

 cacgctcccc gcgcctcggc ttcgcgctcg tgtagatcgt tccctctctg 250

 gttgcacgct ggggatcccg gacctcgatt ctgcgggcga gatgcccctg 300

 ggacacatca tgaggctgga cctggagaaa attgccctgg agtacatcgt 350

 gccctgtctg cacgaggtgg gcttctgcta cctggacaac ttcctgggcg 400

 aggtggtggg cgactgcgtc ctggagcgcg tcaagcagct gcactgcacc 450

 ggggccctgc gggacggcca gctggcgggg ccgcgcgccg gcgtctccaa 500

 gcgacacctg cggggcgacc agatcacgtg gatcgggggc aacgaggagg 550

 gctgcgaggc catcagcttc ctcctgtccc tcatcgacag gctggtcctc 600

 tactgcggga gccggctggg caaatactac gtcaaggaga ggtctaaggc 650

 aatggtggct tgctatccgg gaaatggaac aggttatgtt cgccacgtgg 700

 acaaccccaa cggtgatggt cgctgcatca cctgcatcta ctatctgaac 750

 aagaattggg atgccaagct acatggtggg atcctgcgga tatttccaga 800

 ggggaaatca ttcatagcag atgtggagcc catttttgac agactcctgt 850

 tcttctggtc agatcgtagg aacccacacg aagtgcagcc ctcttacgca 900

 accagatatg ctatgactgt ctggtacttt gatgctgaag aaagggcaga 950

 agccaaaaag aaattcagga atttaactag gaaaactgaa tctgccctca 1000

 ctgaagactg accgtgctct gaaatctgct ggccttgttc attttagtaa 1050

 cggttcctga attctcttaa attctttgag atccaaagat ggcctcttca 1100

 gtgacaacaa tctccctgct acttcttgca tccttcacat ccctgtcttg 1150

 tgtgtggtac ttcatgtttt cttgccaaga ctgtgttgat cttcagatac 1200

 tctctttgcc agatgaagtt atttgctaac tccagaaatt cctgcagaca 1250

 tcctactcgg ccagcggttt acctgataga ttcggtaata ctatcaagag 1300

 aagagcctag gagcacagcg agggaatgaa ccttacttgc actttatgta 1350

 tacttcctga tttgaaagga ggaggtttga aaagaaaaaa atggaggtgg 1400

 tagatgccac agagaggcat cacggaagcc ttaacagcag gaaacagaga 1450

 aatttgtgtc atctgaacaa tttccagatg ttcttaatcc agggctgttg 1500

 gggtttctgg agaattatca caacctaatg acattaatac ctctagaaag 1550

 ggctgctgtc atagtgaaca atttataagt gtcccatggg gcagacactc 1600

 cttttttccc agtcctgcaa cctggatttt ctgcctcagc tccattttgc 1650

 tgaaaataat gactttctga ataaagatgg caacacaaaa aaaaaaaaaa 1700

 aaaaaaa 1707

<210> 3790
<211> 239
<212> PRT
<213> Homo sapien

<400> 3790
 Met Pro Leu Gly His Ile Met Arg Leu Asp Leu Glu Lys Ile Ala
   1               5                  10                  15

 Leu Glu Tyr Ile Val Pro Cys Leu His Glu Val Gly Phe Cys Tyr
                  20                  25                  30

 Leu Asp Asn Phe Leu Gly Glu Val Val Gly Asp Cys Val Leu Glu
                  35                  40                  45

 Arg Val Lys Gln Leu His Cys Thr Gly Ala Leu Arg Asp Gly Gln
                  50                  55                  60

 Leu Ala Gly Pro Arg Ala Gly Val Ser Lys Arg His Leu Arg Gly
                  65                  70                  75

 Asp Gln Ile Thr Trp Ile Gly Gly Asn Glu Glu Gly Cys Glu Ala
                  80                  85                  90

 Ile Ser Phe Leu Leu Ser Leu Ile Asp Arg Leu Val Leu Tyr Cys
                  95                 100                 105

 Gly Ser Arg Leu Gly Lys Tyr Tyr Val Lys Glu Arg Ser Lys Ala
                 110                 115                 120

 Met Val Ala Cys Tyr Pro Gly Asn Gly Thr Gly Tyr Val Arg His
                 125                 130                 135

 Val Asp Asn Pro Asn Gly Asp Gly Arg Cys Ile Thr Cys Ile Tyr
                 140                 145                 150

 Tyr Leu Asn Lys Asn Trp Asp Ala Lys Leu His Gly Gly Ile Leu
                 155                 160                 165

 Arg Ile Phe Pro Glu Gly Lys Ser Phe Ile Ala Asp Val Glu Pro
                 170                 175                 180

 Ile Phe Asp Arg Leu Leu Phe Phe Trp Ser Asp Arg Arg Asn Pro
                 185                 190                 195

 His Glu Val Gln Pro Ser Tyr Ala Thr Arg Tyr Ala Met Thr Val
                 200                 205                 210

 Trp Tyr Phe Asp Ala Glu Glu Arg Ala Glu Ala Lys Lys Lys Phe
                 215                 220                 225

 Arg Asn Leu Thr Arg Lys Thr Glu Ser Ala Leu Thr Glu Asp
                 230                 235

<210> 3791
<211> 1794
<212> DNA
<213> Homo sapien

<400> 3791
 cacatataat aatagcaact cctggtcgac tgattgacca cttgaaacct 50

 ttcgtatttt ccaagtgctg gcaagcgctt cctgcgcagg ccgaggcgac 100

 ctggagtttg tgacgctgtg atggtctaga ggctggagat tcaagatctg 150

 ggtgccatca ttttctggtt ctgttgatga ccctcttcca ggttacatac 200

 agcttacatc ttgcatcctc aagcgttttt cttataaggc taaaaattca 250

 caaagcatat atcaatgaat caggaggatc tagatccgga tagtactaca 300

 gatgtgggag atgttacaaa tactgaagaa gaacttatta gagaatgtga 350

 agaaatgtgg aaagatatgg aagaatgtca gaataaatta tcacttattg 400

 gaactgaaac actcaccgat tcaaatgctc agctatcatt gttaattatg 450

 caagtaaaat gtttaaccgc tgaactcagt caatggcaga aaaaaacacc 500

 tgaaacaatt cccttgactg aagacgttct cataacatta ggaaaagaag 550

 agttccaaaa gctgagacaa gatcttgaaa tggtactgtc cactaaggag 600

 tcaaagaatg aaaagttaaa ggaagactta gaaagggaac aacggtggtt 650

 ggatgaacag caacagataa tggaatctct taatgtacta cacagtgaat 700

 tgaaaaataa ggttgaaaca ttttctgaat caagaatctt taatgaactg 750

 aaaactaaaa tgcttaatat aaaagaatat aaggagaaac tcttgagtac 800

 cttgggcgag tttctagaag accattttcc tctgcctgat agaagtgtta 850

 aaaagaaaaa gaaaaacatt caagaatcat ctgtaaacct gataacactg 900

 catgaaatgt tagagattct tataaataga ttatttgatg ttccacatga 950

 tccatatgtc aaaattagtg attccttttg gccaccttat gttgagctgc 1000

 tgctgcgtaa tggaattgcc ttgagacatc cagaagatcc aacccgaata 1050

 agattagaag ctttccatca gtaaaaggat gttttctttt ttcacacagt 1100

 aaaaattctt atcattcaag gatattggaa ccacaggact atttggataa 1150

 aaaacattat ttgcaaatta atgcgcatag tacttttatt gcaaaatggc 1200

 atgtgctgcc atctattatt catttttaaa tggtcatttc ttattcagtg 1250

 agtgctttag tgttttaaac tatatggata agaatgcagg tagataatat 1300

 tctaggcata aaacatttaa tgtaccttac ctcatgcaat attctttgga 1350

 ttctttgttg atttatgata ttgctaatat aatattttct taaaatatat 1400

 aacaatatct tttatgcatt tgagttccag ctggtgcttc tttatattta 1450

 gaaattataa tgggaaggtc atttaattta cagatggttt taaaattgag 1500

 gtaatatctg aggtggcata atttaaaaat atttagcaaa tttgtttcat 1550

 atatactgtc ttatttctag atttgtttaa aattggaata tgaaaaacta 1600

 atggataaag ctagcataaa attgatattt tagtttgtat tattaatata 1650

 tcatgttacc ttatatatta atctactctt gattctgcta attattacca 1700

 acaaaattgt attcatgaca ttttattaat cctctgtgaa ttttctgtaa 1750

 ataaaattat ttctgaaaat ctctaaaaaa aaaaaaaaaa aaaa 1794

<210> 3792
<211> 269
<212> PRT
<213> Homo sapien

<400> 3792
 Met Asn Gln Glu Asp Leu Asp Pro Asp Ser Thr Thr Asp Val Gly
   1               5                  10                  15

 Asp Val Thr Asn Thr Glu Glu Glu Leu Ile Arg Glu Cys Glu Glu
                  20                  25                  30

 Met Trp Lys Asp Met Glu Glu Cys Gln Asn Lys Leu Ser Leu Ile
                  35                  40                  45

 Gly Thr Glu Thr Leu Thr Asp Ser Asn Ala Gln Leu Ser Leu Leu
                  50                  55                  60

 Ile Met Gln Val Lys Cys Leu Thr Ala Glu Leu Ser Gln Trp Gln
                  65                  70                  75

 Lys Lys Thr Pro Glu Thr Ile Pro Leu Thr Glu Asp Val Leu Ile
                  80                  85                  90

 Thr Leu Gly Lys Glu Glu Phe Gln Lys Leu Arg Gln Asp Leu Glu
                  95                 100                 105

 Met Val Leu Ser Thr Lys Glu Ser Lys Asn Glu Lys Leu Lys Glu
                 110                 115                 120

 Asp Leu Glu Arg Glu Gln Arg Trp Leu Asp Glu Gln Gln Gln Ile
                 125                 130                 135

 Met Glu Ser Leu Asn Val Leu His Ser Glu Leu Lys Asn Lys Val
                 140                 145                 150

 Glu Thr Phe Ser Glu Ser Arg Ile Phe Asn Glu Leu Lys Thr Lys
                 155                 160                 165

 Met Leu Asn Ile Lys Glu Tyr Lys Glu Lys Leu Leu Ser Thr Leu
                 170                 175                 180

 Gly Glu Phe Leu Glu Asp His Phe Pro Leu Pro Asp Arg Ser Val
                 185                 190                 195

 Lys Lys Lys Lys Lys Asn Ile Gln Glu Ser Ser Val Asn Leu Ile
                 200                 205                 210

 Thr Leu His Glu Met Leu Glu Ile Leu Ile Asn Arg Leu Phe Asp
                 215                 220                 225

 Val Pro His Asp Pro Tyr Val Lys Ile Ser Asp Ser Phe Trp Pro
                 230                 235                 240

 Pro Tyr Val Glu Leu Leu Leu Arg Asn Gly Ile Ala Leu Arg His
                 245                 250                 255

 Pro Glu Asp Pro Thr Arg Ile Arg Leu Glu Ala Phe His Gln
                 260                 265

<210> 3793
<211> 4075
<212> DNA
<213> Homo sapien

<400> 3793
 acatgccgga ggaggcgggc ttcccgccgg ccaagagatt ccggccaggc 50

 tctggacctc cgagccgcgc tgggtccttc cctcccggga ggcaagtggt 100

 gatgctgctg actgcgggca gcggcggcag aggaggagga ggaggccgga 150

 ggcagcagcc gcccctggcc cagccctcgg ccagtcccta ccctgaagct 200

 gtggagctgc agcgccggag tctgcccatc ttccaagcgc gggggcaact 250

 gttggcccag ctccgaaacc tggacaacgc ggtcctcatc ggggaaactg 300

 gctctgggaa gacaactcag atccctcagt acctgtatga aggagggatc 350

 agccgccagg gcatcattgc tgtgacccag cctcgtcgag tagctgccat 400

 ctctcttgct actagagtct cagatgagaa gagaactgaa cttgggaagc 450

 tggttggcta tacagtgcgc tttgatgatg tcacctcaga agacaccagg 500

 atcaagtttc tgacagatgg catgcttctg cgtgaagcaa tttcagactc 550

 tttgcttcgg aaatacagct gtgtcatttt ggatgaagct cacgaacgga 600

 ctatccacac agatgtgctc tttggagtgg tgaaagctgc acagaagagg 650

 agaaaggaac tcgggaaact tcctctgaaa gtgattgtga tgtcagctac 700

 gatggatgtg gacctgttct ctcagtattt caatggcgcc cccgtcctct 750

 acctagaggg tcggcagcat ccgatccagg tgttttacac caaacagcct 800

 cagaatgatt acctgcacgc cgcgcttgtc tccgtcttcc agatccacca 850

 ggaagcccct tcttcacagg acatcctggt gttcctcact gggcaggagg 900

 agatcgaagc catgagcaag acgtgccgag acattgcaaa gcacctccca 950

 gacggctgcc ctgcgatgct ggtccttcct ctgtacgcct ccctgcccta 1000

 tgcacagcag ctccgagtct tccaaggggc cccaaagggc tatcgcaaag 1050

 tgatcatttc aaccaacatc gctgaaacct ccataaccat tacaggaata 1100

 aaatatgtag ttgacacggg catggttaaa gcaaagaagt ataaccctga 1150

 cagtggtctt gaggtgttag cagtgcagcg ggtatcgaag acgcaggctt 1200

 ggcagcgcac agggagggct ggcagagagg acagtggcat ctgctaccgg 1250

 ctctacacgg aggacgagtt tgagaagttt gataagatga ccgtgccaga 1300

 gatccagagg tgtaacctgg ccagtgtgat gcttcagctt ctagcaatga 1350

 aagtcccaaa tgtgctcacc tttgacttca tgtcgaagcc atctccagat 1400

 cacattcagg cggccattgc ccaactggac ctgttaggtg ctcttgaaca 1450

 taaggatgac cagcttaccc tgactccaat gggaagaaag atggcagcat 1500

 ttcctttaga acccaaattt gccaaaacca tcctcatgtc ccccaaattc 1550

 cactgtacag aggagatcct gaccattgtc tccctgctgt ctgtggacag 1600

 cgtcctccac aaccctcctt cccggcgaga ggaagtgcaa ggggtccgca 1650

 agaagttcat atccagcgag ggggatcaca tgaccctgct caatatctat 1700

 cggaccttca aaaacctagg cggaaataag gattggtgca aagagaattt 1750

 tgtcaacagc aagaatatga cgctggtagc agaagtcaga gcacagctga 1800

 gggacatctg cttaaagatg tcaatgccaa tcgcatcatc ccgaggagac 1850

 gtggagagtg tccgccgctg cctggctcac agcctcttca tgagcaccgc 1900

 cgagcttcag ccagatggca cctatgccac cacggacacc caccagccag 1950

 tggccatcca cccgtcgtct gtcctcttcc actgcaagcc ggcctgcgtc 2000

 gtgtacactg agctgctcta caccaacaag tgctacatgc gggacctctg 2050

 cgtcatagat gcacagtggc tgtacgaggc tgcccctgag tactttagga 2100

 ggaagctgag aaccgccaga aactgagccg ccccaggatg ccgccagaat 2150

 cactggtccc tgggagcttg gactacagtt gtccttacag caggcttcca 2200

 ggttggcgct tagagaagcc ttggaatcag ctgaaggtgc ctgacttcca 2250

 ggagcgtgaa agcatctttg ctcaactcct gggactgaac catatagaca 2300

 tggacatatc atttgtacct ggaaacctca aaattatgct tttggttctt 2350

 actgggtgac tttgacttaa tttaacacct gagcctcagt tttctcatct 2400

 gccaaatggg agtaataata ataatcctta taaaattggg ttcataaagt 2450

 ttagagaaaa ggaatggaaa gtacccagaa ctatgcctgg agcacgcacg 2500

 acacacgtac agtgagttgg gagccgttag gctgaatgtt actgcttgcc 2550

 atatgatgtg aagtacagca atatcccaag ttcttgtgac tgagggagat 2600

 tttctggaag ggccacagga ggttgcggag cttggatgtt gcccttagtt 2650

 cttgtttaat gtctctctga atgcagtttt aaaatagaaa acaaaactga 2700

 cttctgtaga agtttccaga gggaggtgct gttatctcgt acctcctggg 2750

 atggcgatcc ctactgaacg cttgtgtctc agggtggacc actctgtgtc 2800

 tgtctccaag cagagaccag taaaggagcc tcctggtcct cagtgcgtga 2850

 ccctgtcagt gctttcagga gacatgtaag cttcctgggt gaaggttgat 2900

 ttgtaccttc tgaatcctgt cacgtgtaga catgggaaac tgacctatca 2950

 gtgttttgtg tgtgtaggtg actcccacat acacagttgc catttttctc 3000

 tctaactggg caccagtgaa catgcgggca tgaggagtga ctgtgtacca 3050

 tttcagctgt ttcttttcgg gcagtcccct ggtcagaggg ggtgggggtg 3100

 ggggagggga gaggggtacc tagaacccag agaacattgg cttatgccag 3150

 ataccacacc acatctgggc ttacattctt gtatcttttt tggtgtgtgg 3200

 gcgggggggg tggggggcag ttcagtgaag tctagaagac ctgctggaca 3250

 aattctaaaa gagctagagc tgtaacactt attcttgcat cttattaatt 3300

 ttctatgata ttttttcctt cttcgtaggg acttgggaca atctggcttt 3350

 gctgctttct actgctaggc acctctctct aaccctcatt gtcagaggga 3400

 attggaggat atccacagtc tgttcctgtt ctgatattct gagcagagaa 3450

 aaggcactaa cggttcctct tagctattta attatcagaa gcaagtaatc 3500

 tttccccaga taatattttg ccctagaaga agccgtgatt tagctctttt 3550

 attgtgctta cttggtccaa atacatctgt ggggtgtttt gtcatttctt 3600

 aatgaatgaa tcatagttat aaccaggggc caagctgccc aagaggctct 3650

 tcagagatca tggatgctct ctttctggaa gctgtggcct gatggagcag 3700

 ccccattcca gggtcccatc tgtccggagt tgtgtatgtc aagtccggct 3750

 cagtctttat ttccaacact agccgtggtc ctgtgcagtc aagctctcag 3800

 ctagtgttta gggctgtctg tcagaaatgg ttatacgtgg gcaaaagaag 3850

 atctgacagc tcctatatac cttatcttac tgaattctta aactttgaac 3900

 cagttcttcc acttactgac ttgttaccac tgctgacttt ctgaaaagtt 3950

 ttccagtttt tgttttttgt tttttgtttt ccagtagggg attagaatgt 4000

 ttagtcctac ttagtaagaa aaatattgta tttttaatca ttcatagtgc 4050

 tggtaaaaaa aaaaaaaaaa aaaaa 4075

<210> 3794
<211> 707
<212> PRT
<213> Homo sapien

<400> 3794
 Met Pro Glu Glu Ala Gly Phe Pro Pro Ala Lys Arg Phe Arg Pro
   1               5                  10                  15

 Gly Ser Gly Pro Pro Ser Arg Ala Gly Ser Phe Pro Pro Gly Arg
                  20                  25                  30

 Gln Val Val Met Leu Leu Thr Ala Gly Ser Gly Gly Arg Gly Gly
                  35                  40                  45

 Gly Gly Gly Arg Arg Gln Gln Pro Pro Leu Ala Gln Pro Ser Ala
                  50                  55                  60

 Ser Pro Tyr Pro Glu Ala Val Glu Leu Gln Arg Arg Ser Leu Pro
                  65                  70                  75

 Ile Phe Gln Ala Arg Gly Gln Leu Leu Ala Gln Leu Arg Asn Leu
                  80                  85                  90

 Asp Asn Ala Val Leu Ile Gly Glu Thr Gly Ser Gly Lys Thr Thr
                  95                 100                 105

 Gln Ile Pro Gln Tyr Leu Tyr Glu Gly Gly Ile Ser Arg Gln Gly
                 110                 115                 120

 Ile Ile Ala Val Thr Gln Pro Arg Arg Val Ala Ala Ile Ser Leu
                 125                 130                 135

 Ala Thr Arg Val Ser Asp Glu Lys Arg Thr Glu Leu Gly Lys Leu
                 140                 145                 150

 Val Gly Tyr Thr Val Arg Phe Asp Asp Val Thr Ser Glu Asp Thr
                 155                 160                 165

 Arg Ile Lys Phe Leu Thr Asp Gly Met Leu Leu Arg Glu Ala Ile
                 170                 175                 180

 Ser Asp Ser Leu Leu Arg Lys Tyr Ser Cys Val Ile Leu Asp Glu
                 185                 190                 195

 Ala His Glu Arg Thr Ile His Thr Asp Val Leu Phe Gly Val Val
                 200                 205                 210

 Lys Ala Ala Gln Lys Arg Arg Lys Glu Leu Gly Lys Leu Pro Leu
                 215                 220                 225

 Lys Val Ile Val Met Ser Ala Thr Met Asp Val Asp Leu Phe Ser
                 230                 235                 240

 Gln Tyr Phe Asn Gly Ala Pro Val Leu Tyr Leu Glu Gly Arg Gln
                 245                 250                 255

 His Pro Ile Gln Val Phe Tyr Thr Lys Gln Pro Gln Asn Asp Tyr
                 260                 265                 270

 Leu His Ala Ala Leu Val Ser Val Phe Gln Ile His Gln Glu Ala
                 275                 280                 285

 Pro Ser Ser Gln Asp Ile Leu Val Phe Leu Thr Gly Gln Glu Glu
                 290                 295                 300

 Ile Glu Ala Met Ser Lys Thr Cys Arg Asp Ile Ala Lys His Leu
                 305                 310                 315

 Pro Asp Gly Cys Pro Ala Met Leu Val Leu Pro Leu Tyr Ala Ser
                 320                 325                 330

 Leu Pro Tyr Ala Gln Gln Leu Arg Val Phe Gln Gly Ala Pro Lys
                 335                 340                 345

 Gly Tyr Arg Lys Val Ile Ile Ser Thr Asn Ile Ala Glu Thr Ser
                 350                 355                 360

 Ile Thr Ile Thr Gly Ile Lys Tyr Val Val Asp Thr Gly Met Val
                 365                 370                 375

 Lys Ala Lys Lys Tyr Asn Pro Asp Ser Gly Leu Glu Val Leu Ala
                 380                 385                 390

 Val Gln Arg Val Ser Lys Thr Gln Ala Trp Gln Arg Thr Gly Arg
                 395                 400                 405

 Ala Gly Arg Glu Asp Ser Gly Ile Cys Tyr Arg Leu Tyr Thr Glu
                 410                 415                 420

 Asp Glu Phe Glu Lys Phe Asp Lys Met Thr Val Pro Glu Ile Gln
                 425                 430                 435

 Arg Cys Asn Leu Ala Ser Val Met Leu Gln Leu Leu Ala Met Lys
                 440                 445                 450

 Val Pro Asn Val Leu Thr Phe Asp Phe Met Ser Lys Pro Ser Pro
                 455                 460                 465

 Asp His Ile Gln Ala Ala Ile Ala Gln Leu Asp Leu Leu Gly Ala
                 470                 475                 480

 Leu Glu His Lys Asp Asp Gln Leu Thr Leu Thr Pro Met Gly Arg
                 485                 490                 495

 Lys Met Ala Ala Phe Pro Leu Glu Pro Lys Phe Ala Lys Thr Ile
                 500                 505                 510

 Leu Met Ser Pro Lys Phe His Cys Thr Glu Glu Ile Leu Thr Ile
                 515                 520                 525

 Val Ser Leu Leu Ser Val Asp Ser Val Leu His Asn Pro Pro Ser
                 530                 535                 540

 Arg Arg Glu Glu Val Gln Gly Val Arg Lys Lys Phe Ile Ser Ser
                 545                 550                 555

 Glu Gly Asp His Met Thr Leu Leu Asn Ile Tyr Arg Thr Phe Lys
                 560                 565                 570

 Asn Leu Gly Gly Asn Lys Asp Trp Cys Lys Glu Asn Phe Val Asn
                 575                 580                 585

 Ser Lys Asn Met Thr Leu Val Ala Glu Val Arg Ala Gln Leu Arg
                 590                 595                 600

 Asp Ile Cys Leu Lys Met Ser Met Pro Ile Ala Ser Ser Arg Gly
                 605                 610                 615

 Asp Val Glu Ser Val Arg Arg Cys Leu Ala His Ser Leu Phe Met
                 620                 625                 630

 Ser Thr Ala Glu Leu Gln Pro Asp Gly Thr Tyr Ala Thr Thr Asp
                 635                 640                 645

 Thr His Gln Pro Val Ala Ile His Pro Ser Ser Val Leu Phe His
                 650                 655                 660

 Cys Lys Pro Ala Cys Val Val Tyr Thr Glu Leu Leu Tyr Thr Asn
                 665                 670                 675

 Lys Cys Tyr Met Arg Asp Leu Cys Val Ile Asp Ala Gln Trp Leu
                 680                 685                 690

 Tyr Glu Ala Ala Pro Glu Tyr Phe Arg Arg Lys Leu Arg Thr Ala
                 695                 700                 705

 Arg Asn


<210> 3795
<211> 671
<212> DNA
<213> Homo sapien

<400> 3795
 cttttgccct ctagaaagca actgagccac cgcacccggc cttcattcac 50

 tttctttaaa tgcctccaag ttgattattc tcctagctca tatctccttg 100

 atgtgcatga gggagcactg ggtctaattt ttgggggctg agaaggtaag 150

 aaggtgaggt cagtttttcc caggagtcct aaaaaattct ggtaccttac 200

 attgagggtg tgggagaaag ggtgtcatag ttctgaaaat aggcagtagc 250

 atgaagcacc agacctgtct cattccttat tagatgtcta tctcaaatga 300

 cagagtttga aaaatattgg ttttatcatt tgatatttcc atgcctgact 350

 cgggaaaata acattttctg acttttttct attttcttgc cctgcacaga 400

 ccctacctgg tacaattttc tatttcttag ctcaaagtgt ctatacaatg 450

 ggttgcctgg tatgtcagct gccctcactc ttgtgtaata gaaatatatt 500

 gccaggctgg ggacgtggag gagacgaact ggattcctcc ctcctcctgt 550

 tgccaggcct ctctgcattg gcactttatc ctttcagtgt ttctggctgt 600

 gttgggttca tttgtgagac tgatgtaaca ataaagtgaa atcttcccct 650

 ctgaaaaaaa aaaaaaaagg g 671

<210> 3796
<211> 46
<212> PRT
<213> Homo sapien

<400> 3796
 Leu Leu Pro Ser Arg Lys Gln Leu Ser His Arg Thr Arg Pro Ser
   1               5                  10                  15

 Phe Thr Phe Phe Lys Cys Leu Gln Val Asp Tyr Ser Pro Ser Ser
                  20                  25                  30

 Tyr Leu Leu Asp Val His Glu Gly Ala Leu Gly Leu Ile Phe Gly
                  35                  40                  45

 Gly


<210> 3797
<211> 2794
<212> DNA
<213> Homo sapien

<400> 3797
 aggagcctac tttattctga taaaacaggt ctatgcagct accaggacaa 50

 tggaatctac gttgacttta gcaacggaac aacctgttaa gaagaacact 100

 cttaagaaat ataaaatagc ttgcattgtt cttcttgctt tgctggtgat 150

 catgtcactt ggattaggcc tggggcttgg actcaggaaa ctggaaaagc 200

 aaggcagctg caggaagaag tgctttgatg catcatttag aggactggag 250

 aactgccggt gtgatgtggc atgtaaagac cgaggtgatt gctgctggga 300

 ttttgaagac acctgtgtgg aatcaactcg aatatggatg tgcaataaat 350

 ttcgttgtgg agagaccaga ttagaggcca gcctttgctc ttgttcagat 400

 gactgtttgc agaagaaaga ttgctgtgct gactataaga gtgtttgcca 450

 aggagaaacc tcatggctgg aagaaaactg tgacacagcc cagcagtctc 500

 agtgcccaga agggtttgac ctgccaccag ttatcttgtt ttctatggat 550

 ggatttagag ctgaatattt atacacatgg gatactttaa tgccaaatat 600

 caataaactg aaaacatgtg gaattcattc aaaatacatg agagctatgt 650

 atcctaccaa aaccttccca aatcattaca ccattgtcac gggcttgtat 700

 ccagagtcac atggcatcat tgacaataat atgtatgatg taaatctcaa 750

 caagaatttt tcactttctt caaaggaaca aaataatcca gcctggtggc 800

 atgggcaacc aatgtggctg acagcaatgt atcaaggttt aaaagccgct 850

 acctactttt ggcccggatc agaagtggct ataaatggct cctttccttc 900

 catatacatg ccttacaacg gaagtgtccc atttgaagag aggatttcta 950

 cactgttaaa atggctggac ctgcccaaag ctgaaagacc caggttttat 1000

 accatgtatt ttgaagaacc tgattcctct ggacatgcag gtggaccagt 1050

 cagtgccaga gtaattaaag ccttacaggt agtagatcat gcttttggga 1100

 tgttgatgga aggcctgaag cagcggaatt tgcacaactg tgtcaatatc 1150

 atccttctgg ctgaccatgg aatggaccag acttattgta acaagatgga 1200

 atacatgact gattattttc ccagaataaa cttcttctac atgtacgaag 1250

 ggcctgcccc ccgcatccga gctcataata tacctcatga cttttttagt 1300

 tttaattctg aggaaattgt tagaaacctc agttgccgaa aacctgatca 1350

 gcatttcaag ccctatttga ctcctgattt gccaaagcga ctgcactatg 1400

 ccaagaacgt cagaatcgac aaagttcatc tctttgtgga tcaacagtgg 1450

 ctggctgtta ggagtaaatc aaatacaaat tgtggaggag gcaaccatgg 1500

 ttataacaat gagtttagga gcatggaggc tatctttctg gcacatggac 1550

 ccagttttaa agagaagact gaagttgaac catttgaaaa tattgaagtc 1600

 tataacctaa tgtgtgatct tctacgcatt caaccagcac caaacaatgg 1650

 aacccatggt agtttaaacc atcttctgaa ggtgcctttt tatgagccat 1700

 cccatgcaga ggaggtgtca aagttttctg tttgtggctt tgctaatcca 1750

 ttgcccacag agtctcttga ctgtttctgc cctcacctac aaaatagtac 1800

 tcagctggaa caagtgaatc agatgctaaa tctcacccaa gaagaaataa 1850

 cagcaacagt gaaagtaaat ttgccatttg ggaggcctag ggtactgcag 1900

 aagaacgtgg accactgtct cctttaccac agggaatatg tcagtggatt 1950

 tggaaaagct atgaggatgc ccatgtggag ttcatacaca gtcccccagt 2000

 tgggagacac atcgcctctg cctcccactg tcccagactg tctgcgggct 2050

 gatgtcaggg ttcctccttc tgagagccaa aaatgttcct tctatttagc 2100

 agacaagaat atcacccacg gcttcctcta tcctcctgcc agcaatagaa 2150

 catcagatag ccaatatgat gctttaatta ctagcaattt ggtacctatg 2200

 tatgaagaat tcagaaaaat gtgggactac ttccacagtg ttcttcttat 2250

 aaaacatgcc acagaaagaa atggagtaaa tgtggttagt ggaccaatat 2300

 ttgattataa ttatgatggc cattttgatg ctccagatga aattaccaaa 2350

 catttagcca acactgatgt tcccatccca acacactact ttgtggtgct 2400

 gaccagttgt aaaaacaaga gccacacacc ggaaaactgc cctgggtggc 2450

 tggatgtcct accctttatc atccctcacc gacctaccaa cgtggagagc 2500

 tgtcctgaag gtaaaccaga agctctttgg gttgaagaaa gatttacagc 2550

 tcacattgcc cgggtccgtg atgtagaact tctcactggg cttgacttct 2600

 atcaggataa agtgcagcct gtctctgaaa ttttgcaact aaagacatat 2650

 ttaccaacat ttgaaaccac tatttaactt aataatgtct acttaatata 2700

 taatttactg tataaagtaa ttttggcaaa atataagtga tttttttctg 2750

 gagaattgta aaataaagtt ttctattttt ccttaaaaaa aaaa 2794

<210> 3798
<211> 875
<212> PRT
<213> Homo sapien

<400> 3798
 Met Glu Ser Thr Leu Thr Leu Ala Thr Glu Gln Pro Val Lys Lys
   1               5                  10                  15

 Asn Thr Leu Lys Lys Tyr Lys Ile Ala Cys Ile Val Leu Leu Ala
                  20                  25                  30

 Leu Leu Val Ile Met Ser Leu Gly Leu Gly Leu Gly Leu Gly Leu
                  35                  40                  45

 Arg Lys Leu Glu Lys Gln Gly Ser Cys Arg Lys Lys Cys Phe Asp
                  50                  55                  60

 Ala Ser Phe Arg Gly Leu Glu Asn Cys Arg Cys Asp Val Ala Cys
                  65                  70                  75

 Lys Asp Arg Gly Asp Cys Cys Trp Asp Phe Glu Asp Thr Cys Val
                  80                  85                  90

 Glu Ser Thr Arg Ile Trp Met Cys Asn Lys Phe Arg Cys Gly Glu
                  95                 100                 105

 Thr Arg Leu Glu Ala Ser Leu Cys Ser Cys Ser Asp Asp Cys Leu
                 110                 115                 120

 Gln Lys Lys Asp Cys Cys Ala Asp Tyr Lys Ser Val Cys Gln Gly
                 125                 130                 135

 Glu Thr Ser Trp Leu Glu Glu Asn Cys Asp Thr Ala Gln Gln Ser
                 140                 145                 150

 Gln Cys Pro Glu Gly Phe Asp Leu Pro Pro Val Ile Leu Phe Ser
                 155                 160                 165

 Met Asp Gly Phe Arg Ala Glu Tyr Leu Tyr Thr Trp Asp Thr Leu
                 170                 175                 180

 Met Pro Asn Ile Asn Lys Leu Lys Thr Cys Gly Ile His Ser Lys
                 185                 190                 195

 Tyr Met Arg Ala Met Tyr Pro Thr Lys Thr Phe Pro Asn His Tyr
                 200                 205                 210

 Thr Ile Val Thr Gly Leu Tyr Pro Glu Ser His Gly Ile Ile Asp
                 215                 220                 225

 Asn Asn Met Tyr Asp Val Asn Leu Asn Lys Asn Phe Ser Leu Ser
                 230                 235                 240

 Ser Lys Glu Gln Asn Asn Pro Ala Trp Trp His Gly Gln Pro Met
                 245                 250                 255

 Trp Leu Thr Ala Met Tyr Gln Gly Leu Lys Ala Ala Thr Tyr Phe
                 260                 265                 270

 Trp Pro Gly Ser Glu Val Ala Ile Asn Gly Ser Phe Pro Ser Ile
                 275                 280                 285

 Tyr Met Pro Tyr Asn Gly Ser Val Pro Phe Glu Glu Arg Ile Ser
                 290                 295                 300

 Thr Leu Leu Lys Trp Leu Asp Leu Pro Lys Ala Glu Arg Pro Arg
                 305                 310                 315

 Phe Tyr Thr Met Tyr Phe Glu Glu Pro Asp Ser Ser Gly His Ala
                 320                 325                 330

 Gly Gly Pro Val Ser Ala Arg Val Ile Lys Ala Leu Gln Val Val
                 335                 340                 345

 Asp His Ala Phe Gly Met Leu Met Glu Gly Leu Lys Gln Arg Asn
                 350                 355                 360

 Leu His Asn Cys Val Asn Ile Ile Leu Leu Ala Asp His Gly Met
                 365                 370                 375

 Asp Gln Thr Tyr Cys Asn Lys Met Glu Tyr Met Thr Asp Tyr Phe
                 380                 385                 390

 Pro Arg Ile Asn Phe Phe Tyr Met Tyr Glu Gly Pro Ala Pro Arg
                 395                 400                 405

 Ile Arg Ala His Asn Ile Pro His Asp Phe Phe Ser Phe Asn Ser
                 410                 415                 420

 Glu Glu Ile Val Arg Asn Leu Ser Cys Arg Lys Pro Asp Gln His
                 425                 430                 435

 Phe Lys Pro Tyr Leu Thr Pro Asp Leu Pro Lys Arg Leu His Tyr
                 440                 445                 450

 Ala Lys Asn Val Arg Ile Asp Lys Val His Leu Phe Val Asp Gln
                 455                 460                 465

 Gln Trp Leu Ala Val Arg Ser Lys Ser Asn Thr Asn Cys Gly Gly
                 470                 475                 480

 Gly Asn His Gly Tyr Asn Asn Glu Phe Arg Ser Met Glu Ala Ile
                 485                 490                 495

 Phe Leu Ala His Gly Pro Ser Phe Lys Glu Lys Thr Glu Val Glu
                 500                 505                 510

 Pro Phe Glu Asn Ile Glu Val Tyr Asn Leu Met Cys Asp Leu Leu
                 515                 520                 525

 Arg Ile Gln Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn
                 530                 535                 540

 His Leu Leu Lys Val Pro Phe Tyr Glu Pro Ser His Ala Glu Glu
                 545                 550                 555

 Val Ser Lys Phe Ser Val Cys Gly Phe Ala Asn Pro Leu Pro Thr
                 560                 565                 570

 Glu Ser Leu Asp Cys Phe Cys Pro His Leu Gln Asn Ser Thr Gln
                 575                 580                 585

 Leu Glu Gln Val Asn Gln Met Leu Asn Leu Thr Gln Glu Glu Ile
                 590                 595                 600

 Thr Ala Thr Val Lys Val Asn Leu Pro Phe Gly Arg Pro Arg Val
                 605                 610                 615

 Leu Gln Lys Asn Val Asp His Cys Leu Leu Tyr His Arg Glu Tyr
                 620                 625                 630

 Val Ser Gly Phe Gly Lys Ala Met Arg Met Pro Met Trp Ser Ser
                 635                 640                 645

 Tyr Thr Val Pro Gln Leu Gly Asp Thr Ser Pro Leu Pro Pro Thr
                 650                 655                 660

 Val Pro Asp Cys Leu Arg Ala Asp Val Arg Val Pro Pro Ser Glu
                 665                 670                 675

 Ser Gln Lys Cys Ser Phe Tyr Leu Ala Asp Lys Asn Ile Thr His
                 680                 685                 690

 Gly Phe Leu Tyr Pro Pro Ala Ser Asn Arg Thr Ser Asp Ser Gln
                 695                 700                 705

 Tyr Asp Ala Leu Ile Thr Ser Asn Leu Val Pro Met Tyr Glu Glu
                 710                 715                 720

 Phe Arg Lys Met Trp Asp Tyr Phe His Ser Val Leu Leu Ile Lys
                 725                 730                 735

 His Ala Thr Glu Arg Asn Gly Val Asn Val Val Ser Gly Pro Ile
                 740                 745                 750

 Phe Asp Tyr Asn Tyr Asp Gly His Phe Asp Ala Pro Asp Glu Ile
                 755                 760                 765

 Thr Lys His Leu Ala Asn Thr Asp Val Pro Ile Pro Thr His Tyr
                 770                 775                 780

 Phe Val Val Leu Thr Ser Cys Lys Asn Lys Ser His Thr Pro Glu
                 785                 790                 795

 Asn Cys Pro Gly Trp Leu Asp Val Leu Pro Phe Ile Ile Pro His
                 800                 805                 810

 Arg Pro Thr Asn Val Glu Ser Cys Pro Glu Gly Lys Pro Glu Ala
                 815                 820                 825

 Leu Trp Val Glu Glu Arg Phe Thr Ala His Ile Ala Arg Val Arg
                 830                 835                 840

 Asp Val Glu Leu Leu Thr Gly Leu Asp Phe Tyr Gln Asp Lys Val
                 845                 850                 855

 Gln Pro Val Ser Glu Ile Leu Gln Leu Lys Thr Tyr Leu Pro Thr
                 860                 865                 870

 Phe Glu Thr Thr Ile
                 875

<210> 3799
<211> 2657
<212> DNA
<213> Homo sapien

<400> 3799
 tatatcaata caccagtggc tgaaattatc atgaaaccaa atgttggaca 50

 aggcagcaca agtgtgcaaa cagctatgga aagtgaactc ggagagtcta 100

 gtgccacaat caataaaaga ctctgcaaaa gtacaataga actttcagaa 150

 aattctttac ttccagcttc ttctatgttg actggcacac aaagtaaggc 200

 tgttgctttc aatgcatgca atattaactt tgagtgttta ctaactctgt 250

 gttttgctta cctggctttt cttccttgaa gttgcttttt tttttcctcc 300

 aagaggaatt atttaaaaag actttagtct gtgacataac caagatttat 350

 tctgtttacc taaggaactt attttctttt ttgcaatttc atttattctg 400

 agtcacttta tttgtaataa gtgaagaatt ttaatactta gaaataagtt 450

 gtaaagaaaa taatgagaat cttaccatgc tttagaggaa cgtaatttct 500

 agaaatagtt aaaagatgaa atactaagat attattttac cttctttata 550

 tagctgtata tactggtagt atgaaagcaa ctagtgtcat tgatgatttt 600

 ttgggggggt atttttgtat tctaggcttg ctgcaacctc atttagagag 650

 ggttgccatc gatgctctac agttatgttg tttgttactt cccccaccaa 700

 atcgtagaaa gcttcaactt ttaatgcgta tgatttcccg aatgagtcaa 750

 aatgttgata tgcccaaact tcatgatgca atgggtacga ggtcactgat 800

 gatacatacc ttttctcgat gtgtgttatg ctgtgctgaa gaagtggatc 850

 ttgatgagct tcttgctgga agattagttt ctttcttaat ggatcatcat 900

 caggaaattc ttcaagtacc ctcttactta cagactgcag tggaaaaaca 950

 tcttgactac ttaaaaaagg gacatattga aaatcctgga gatggactat 1000

 ttgctccttt gccaacttac tcatactgta agcagattag tgctcaggag 1050

 tttgatgagc aaaaagtttc tacctctcaa gctgcaattg cagaactttt 1100

 agaaaatatt attaaaaaca ggagtttacc tctaaaggag aaaagaaaaa 1150

 aactaaaaca gtttcagaag gaatatcctt tgatatatca gaaaagattt 1200

 ccaaccacgg agagtgaagc agcacttttt ggtgacaaac ctacaatcaa 1250

 gcaaccaatg ctgattttaa gaaaaccaaa gttccgtagt ctaagataac 1300

 taactgaatt aaaaattatg taatacttgt ggaactttga taaatgaagc 1350

 catatctgag aatgtagcta ctcaaaagga agtctgtcat taataaggta 1400

 tttctaaata aacacattat gtaaggaagt gccaaaatag ttatcaatgt 1450

 gagactctta ggaaactaac tagatctcaa ttgagagcac ataacaatag 1500

 atgataccaa atactttttg tttttaacac agctatccag taaggctatc 1550

 atgatgtgtg ctaaaatttt atttacttga attttgaaaa ctgagctgtg 1600

 ttagggatta aactataatt ctgttcttaa aagaaaattt atctgcaaat 1650

 gtgcaagttc tgagatatta gctaatgaat tagttgtttg gggttacttc 1700

 tttgtttcta agtataagaa tgtgaagaat atttgaaaac tcaatggaat 1750

 aattctcagc tgccaaatgt tgcactcttt tatatattct ttttccactt 1800

 ttgatctatt tatatatatg tatgtgtttt taaaatatgt gtatatttta 1850

 tcagatttgg ttttgcctta aatattatcc ccaattgctt cagtcattca 1900

 tttgttcagt atatatattt tgaattctag ttttcataat ctattagaag 1950

 atggggatat aaaagaagta taaggcaatc atatattcat tcaaaagata 2000

 tttatttagc aactgctatg tgcctttcgt tgttccagat atgcagagac 2050

 aatgataaat aaaacatata atctcttcca taaggtattt attttttaat 2100

 caagggagat acacctatca gatgtttaaa ataacaacac tacccactga 2150

 aatcagggca tatagaatca ttcagctaaa gagtgacttc tatgatgatg 2200

 gaacaggtct ctaagctagt ggttttcaaa ctggtacaca ttagactcac 2250

 ccgaggaatt ttaaaacagc ctatatgccc agggcctaac ttacactaat 2300

 taaatctgaa ttttggggat gttgtatagg gattagtatt ttttttaatc 2350

 taggtgattc caatattcag ccaactgtga gaatcaatgg cctaaatgct 2400

 ttttataaac atttttataa gtgtcaagat aatggcacat tgactttatt 2450

 ttttcattgg aagaaaatgc ctgccaagta taaatgactc tcatcttaaa 2500

 acaaggttct tcaggtttct gcttgattga cttggtacaa acttgaagca 2550

 agttgccttc taatttttac tccaagattg tttcatatct attccttaag 2600

 tgtaaagaaa tatataatgc atggtttgta ataaaatctt aatgtttaat 2650

 gactgtt 2657

<210> 3800
<211> 242
<212> PRT
<213> Homo sapien

<400> 3800
 Met Lys Ala Thr Ser Val Ile Asp Asp Phe Leu Gly Gly Tyr Phe
   1               5                  10                  15

 Cys Ile Leu Gly Leu Leu Gln Pro His Leu Glu Arg Val Ala Ile
                  20                  25                  30

 Asp Ala Leu Gln Leu Cys Cys Leu Leu Leu Pro Pro Pro Asn Arg
                  35                  40                  45

 Arg Lys Leu Gln Leu Leu Met Arg Met Ile Ser Arg Met Ser Gln
                  50                  55                  60

 Asn Val Asp Met Pro Lys Leu His Asp Ala Met Gly Thr Arg Ser
                  65                  70                  75

 Leu Met Ile His Thr Phe Ser Arg Cys Val Leu Cys Cys Ala Glu
                  80                  85                  90

 Glu Val Asp Leu Asp Glu Leu Leu Ala Gly Arg Leu Val Ser Phe
                  95                 100                 105

 Leu Met Asp His His Gln Glu Ile Leu Gln Val Pro Ser Tyr Leu
                 110                 115                 120

 Gln Thr Ala Val Glu Lys His Leu Asp Tyr Leu Lys Lys Gly His
                 125                 130                 135

 Ile Glu Asn Pro Gly Asp Gly Leu Phe Ala Pro Leu Pro Thr Tyr
                 140                 145                 150

 Ser Tyr Cys Lys Gln Ile Ser Ala Gln Glu Phe Asp Glu Gln Lys
                 155                 160                 165

 Val Ser Thr Ser Gln Ala Ala Ile Ala Glu Leu Leu Glu Asn Ile
                 170                 175                 180

 Ile Lys Asn Arg Ser Leu Pro Leu Lys Glu Lys Arg Lys Lys Leu
                 185                 190                 195

 Lys Gln Phe Gln Lys Glu Tyr Pro Leu Ile Tyr Gln Lys Arg Phe
                 200                 205                 210

 Pro Thr Thr Glu Ser Glu Ala Ala Leu Phe Gly Asp Lys Pro Thr
                 215                 220                 225

 Ile Lys Gln Pro Met Leu Ile Leu Arg Lys Pro Lys Phe Arg Ser
                 230                 235                 240

 Leu Arg


<210> 3801
<211> 2974
<212> DNA
<213> Homo sapien

<400> 3801
 ggaggaagcg gtggctgctg cggatgtcgg tgtgagcgag cggcgcctga 50

 acacacggcg gctgccgagc gcctgacccg ggcctgcgcc agagcctgca 100

 ccgagctccg gggccccaca cccgctacgg tggccctgcg cccgttgcta 150

 ctgaggcggc gtgctctgca ttcttcgctg tccaggcctg ccggctctgg 200

 tgtctgctgg ctcctccttg ctcgcctgct ccctcctgct tgcctgagtc 250

 accgccgccg ccgccgccac agccatggcc gagagtggtg aaagcggcgg 300

 tcctccgggc tcccaggata gcgccgccgg agccgaaggt gctggcgccc 350

 ccgcggccgc tgcctccgcg gagcccaaaa tcatgaaagt caccgtgaag 400

 accccgaagg aaaaggagga attcgccgtg cccgagaata gctccgtcca 450

 gcagtttaag gaagaaatct ctaaacgttt taaatcacat actgaccaac 500

 ttgtgttgat atttgctgga aaaattttga aagatcaaga taccttgagt 550

 cagcatggaa ttcatgatgg acttactgtt caccttgtca ttaaaacaca 600

 aaacaggcct caggatcatt cagctcagca aacaaataca gctggaagca 650

 atgttactac atcatcaact cctaatagta actctacatc tggttctgct 700

 actagcaacc cttttggttt aggtggcctt gggggacttg caggtctgag 750

 tagcttgggt ttgaatacta ccaacttctc tgaactacag agtcagatgc 800

 agcgacaact tttgtctaac cctgaaatga tggtccagat catggaaaat 850

 ccctttgttc agagcatgct ctcaaatcct gacctgatga gacagttaat 900

 tatggccaat ccacaaatgc agcagttgat acagagaaat ccagaaatta 950

 gtcatatgtt gaataatcca gatataatga gacaaacgtt ggaacttgcc 1000

 aggaatccag caatgatgca ggagatgatg aggaaccagg accgagcttt 1050

 gagcaaccta gaaagcatcc cagggggata taatgcttta aggcgcatgt 1100

 acacagatat tcaggaacca atgctgagtg ctgcacaaga gcagtttggt 1150

 ggtaatccat ttgcttcctt ggtgagcaat acatcctctg gtgaaggtag 1200

 tcaaccttcc cgtacagaaa atagagatcc actacccaat ccatgggctc 1250

 cacagacttc ccagagttca tcagcttcca gcggcactgc cagcactgtg 1300

 ggtggcacta ctggtagtac tgccagtggc acttctgggc agagtactac 1350

 tgcgccaaat ttggtgcctg gagtaggagc tagtatgttc aacacaccag 1400

 gaatgcagag cttgttgcaa caaataactg aaaacccaca actgatgcaa 1450

 aacatgttgt ctgcccccta catgagaagc atgatgcagt cactaagcca 1500

 gaatcctgac cttgctgcac agatgatgct gaataatccc ctatttgctg 1550

 gaaatcctca gcttcaagaa caaatgagac aacagctccc aactttcctc 1600

 caacaaatgc agaatcctga tacactatca gcaatgtcaa accctagagc 1650

 aatgcaggcc ttgttacaga ttcagcaggg tttacagaca ttagcaacgg 1700

 aagccccggg cctcatccca gggtttactc ctggcttggg ggcattagga 1750

 agcactggag gctcttcggg aactaatgga tctaacgcca cacctagtga 1800

 aaacacaagt cccacagcag gaaccactga acctggacat cagcagttta 1850

 ttcagcagat gctgcaggct cttgctggag taaatcctca gctacagaat 1900

 ccagaagtca gatttcagca acaactggaa caactcagtg caatgggatt 1950

 tttgaaccgt gaagcaaact tgcaagctct aatagcaaca ggaggtgata 2000

 tcaatgcagc tattgaaagg ttactgggct cccagccatc atagcagcat 2050

 ttctgtatct tgaaaaaatg taatttattt ttgataacgg ctcttaaact 2100

 ttaaaatacc tgctttattt cattttgact cttggaattc tgtgctgtta 2150

 taaacaaacc caatatgatg cattttaagg tggagtacag taagatgtgt 2200

 gggtttttct gtatttttct tttctggaac agtgggaatt aaggctactg 2250

 catgcatcac ttctgcattt attgtaattt tttaaaaaca tcacctttta 2300

 tagttgggtg accagatttt gtcctgcatc tgtccagttt atttgctttt 2350

 taaacattag cctatggtag taatttatgt agaataaaag cattaaaaag 2400

 aagcaaatca tttgcactct ataatttgtg gtacagtatt gcttattgtg 2450

 actttggcat gcatttttgc aaacaatgct gtaagattta tactactgat 2500

 aattttgttt tatttgtata caatatagag tatgcacatt tgggactgca 2550

 tttctggaaa catactgcaa taggctctct gagcaaaaca cctgtaacta 2600

 aaaaagtgaa gataagaaaa tactcttaaa gctgagtatt tcctaattgt 2650

 atagaatctt acagcatctt tgacaaacat ctcccagcaa aagtgccggt 2700

 tagtcaggtt tgttgaaaat acagtagaaa agctgattct ggttatctct 2750

 ttaaggacaa ttaattgtac agacacataa tgtaacattg tctcaacatt 2800

 cattcacaga ttgactgtaa attaccttaa tctttgtgca gactgaagga 2850

 acactgtagt ataccccaaa gtgcatttgc ctaggacttc tcagcttctc 2900

 ccataggtag tttaacaggc attaaaattt gtaattgaaa tgttgctttc 2950

 actcaaaaaa aaaaaaaaaa aaaa 2974

<210> 3802
<211> 589
<212> PRT
<213> Homo sapien

<400> 3802
 Met Ala Glu Ser Gly Glu Ser Gly Gly Pro Pro Gly Ser Gln Asp
   1               5                  10                  15

 Ser Ala Ala Gly Ala Glu Gly Ala Gly Ala Pro Ala Ala Ala Ala
                  20                  25                  30

 Ser Ala Glu Pro Lys Ile Met Lys Val Thr Val Lys Thr Pro Lys
                  35                  40                  45

 Glu Lys Glu Glu Phe Ala Val Pro Glu Asn Ser Ser Val Gln Gln
                  50                  55                  60

 Phe Lys Glu Glu Ile Ser Lys Arg Phe Lys Ser His Thr Asp Gln
                  65                  70                  75

 Leu Val Leu Ile Phe Ala Gly Lys Ile Leu Lys Asp Gln Asp Thr
                  80                  85                  90

 Leu Ser Gln His Gly Ile His Asp Gly Leu Thr Val His Leu Val
                  95                 100                 105

 Ile Lys Thr Gln Asn Arg Pro Gln Asp His Ser Ala Gln Gln Thr
                 110                 115                 120

 Asn Thr Ala Gly Ser Asn Val Thr Thr Ser Ser Thr Pro Asn Ser
                 125                 130                 135

 Asn Ser Thr Ser Gly Ser Ala Thr Ser Asn Pro Phe Gly Leu Gly
                 140                 145                 150

 Gly Leu Gly Gly Leu Ala Gly Leu Ser Ser Leu Gly Leu Asn Thr
                 155                 160                 165

 Thr Asn Phe Ser Glu Leu Gln Ser Gln Met Gln Arg Gln Leu Leu
                 170                 175                 180

 Ser Asn Pro Glu Met Met Val Gln Ile Met Glu Asn Pro Phe Val
                 185                 190                 195

 Gln Ser Met Leu Ser Asn Pro Asp Leu Met Arg Gln Leu Ile Met
                 200                 205                 210

 Ala Asn Pro Gln Met Gln Gln Leu Ile Gln Arg Asn Pro Glu Ile
                 215                 220                 225

 Ser His Met Leu Asn Asn Pro Asp Ile Met Arg Gln Thr Leu Glu
                 230                 235                 240

 Leu Ala Arg Asn Pro Ala Met Met Gln Glu Met Met Arg Asn Gln
                 245                 250                 255

 Asp Arg Ala Leu Ser Asn Leu Glu Ser Ile Pro Gly Gly Tyr Asn
                 260                 265                 270

 Ala Leu Arg Arg Met Tyr Thr Asp Ile Gln Glu Pro Met Leu Ser
                 275                 280                 285

 Ala Ala Gln Glu Gln Phe Gly Gly Asn Pro Phe Ala Ser Leu Val
                 290                 295                 300

 Ser Asn Thr Ser Ser Gly Glu Gly Ser Gln Pro Ser Arg Thr Glu
                 305                 310                 315

 Asn Arg Asp Pro Leu Pro Asn Pro Trp Ala Pro Gln Thr Ser Gln
                 320                 325                 330

 Ser Ser Ser Ala Ser Ser Gly Thr Ala Ser Thr Val Gly Gly Thr
                 335                 340                 345

 Thr Gly Ser Thr Ala Ser Gly Thr Ser Gly Gln Ser Thr Thr Ala
                 350                 355                 360

 Pro Asn Leu Val Pro Gly Val Gly Ala Ser Met Phe Asn Thr Pro
                 365                 370                 375

 Gly Met Gln Ser Leu Leu Gln Gln Ile Thr Glu Asn Pro Gln Leu
                 380                 385                 390

 Met Gln Asn Met Leu Ser Ala Pro Tyr Met Arg Ser Met Met Gln
                 395                 400                 405

 Ser Leu Ser Gln Asn Pro Asp Leu Ala Ala Gln Met Met Leu Asn
                 410                 415                 420

 Asn Pro Leu Phe Ala Gly Asn Pro Gln Leu Gln Glu Gln Met Arg
                 425                 430                 435

 Gln Gln Leu Pro Thr Phe Leu Gln Gln Met Gln Asn Pro Asp Thr
                 440                 445                 450

 Leu Ser Ala Met Ser Asn Pro Arg Ala Met Gln Ala Leu Leu Gln
                 455                 460                 465

 Ile Gln Gln Gly Leu Gln Thr Leu Ala Thr Glu Ala Pro Gly Leu
                 470                 475                 480

 Ile Pro Gly Phe Thr Pro Gly Leu Gly Ala Leu Gly Ser Thr Gly
                 485                 490                 495

 Gly Ser Ser Gly Thr Asn Gly Ser Asn Ala Thr Pro Ser Glu Asn
                 500                 505                 510

 Thr Ser Pro Thr Ala Gly Thr Thr Glu Pro Gly His Gln Gln Phe
                 515                 520                 525

 Ile Gln Gln Met Leu Gln Ala Leu Ala Gly Val Asn Pro Gln Leu
                 530                 535                 540

 Gln Asn Pro Glu Val Arg Phe Gln Gln Gln Leu Glu Gln Leu Ser
                 545                 550                 555

 Ala Met Gly Phe Leu Asn Arg Glu Ala Asn Leu Gln Ala Leu Ile
                 560                 565                 570

 Ala Thr Gly Gly Asp Ile Asn Ala Ala Ile Glu Arg Leu Leu Gly
                 575                 580                 585

 Ser Gln Pro Ser


<210> 3803
<211> 1511
<212> DNA
<213> Homo sapien

<400> 3803
 ctcattcgtt cccagcaggc cctgcgcgcg gcaacatggc ggggtccagg 50

 tggaggtctt gaggctatca gatcggtatg gcattggcgt ccgggcccgc 100

 aaggcgggcg ctagctggct ccgggcagct cggccttggg ggcttcgggg 150

 ccccgagacg cggggcgtat gagtggggcg tgcgctccac gcggaagtcg 200

 gagcctcctc ccctggatag ggtgtacgag atccctggac tggagcccat 250

 cacctttgcg gggaagatgc acttcgtgcc ctggctggcg cggccgatct 300

 ttccgccctg ggaccgcggc tacaaggacc caaggttcta ccgctcgccc 350

 cctcttcacg agcatccgct gtacaaagac caggcctgct atatctttca 400

 ccaccgttgc cgccttctcg agggtgtaaa gcaggccctc tggctcacca 450

 agaccaagtt aatagaaggc cttcccgaga aagtgcttag ccttgttgat 500

 gatccaagga accacataga gaaccaagac gagtgcgttc tgaatgtgat 550

 ctctcacgcc cgtctctggc agaccactga ggaaatcccc aagagagaga 600

 cctactgccc ggtcatcgtg gacaacctaa tacagctgtg taaatctcag 650

 attctcaagc atccttctct ggccaggagg atctgtgtcc aaaactccac 700

 gttttctgct acctggaacc gagagtctct tctccttcaa gtccgtggtt 750

 ctggtggagc ccgactgagc actaaggatc ctctgcccac catcgcctcc 800

 agagaggaga ttgaagctac taagaatcat gttctagaga ccttctaccc 850

 catatcaccc atcatcgatc ttcatgaatg caatatttat gatgtgaaaa 900

 atgacacagg attccaggaa ggctatcctt acccctatcc ccataccctg 950

 tacttactgg acaaagccaa tttacgacca caccgccttc aaccagatca 1000

 gctgcgggcc aagatgatcc tgtttgcttt tggcagtgcc ctggctcagg 1050

 cccggctcct ctatgggaat gatgccaagg tcttggagca gcccgtggtg 1100

 gtgcagagcg tgggcacgga tggacgtgtc ttccatttcc tagtgtttca 1150

 actgaatacc acagacctgg actgtaacga gggtgtcaag aatttggcct 1200

 gggtggactc agaccagctc ctctatcagc atttttggtg tctcccagtg 1250

 atcaaaaaga gagtggttgt ggaacctgtt gggccagttg gtttcaagcc 1300

 agagacattc agaaagtttt tagctctata tttgcatggt gctgcgtgag 1350

 cggaggaccc ctctgaatcc tgaaacccct cttgcctctc ttccacggaa 1400

 gagggcctgg gccccgtgga gcctcagtgc ccgtttggcc tgctgctctc 1450

 gctgacaata aagagccctt gcgttgcaaa aaaaaaaaaa aaaaaaaaaa 1500

 aaaaaaaaaa a 1511

<210> 3804
<211> 423
<212> PRT
<213> Homo sapien

<400> 3804
 Met Ala Leu Ala Ser Gly Pro Ala Arg Arg Ala Leu Ala Gly Ser
   1               5                  10                  15

 Gly Gln Leu Gly Leu Gly Gly Phe Gly Ala Pro Arg Arg Gly Ala
                  20                  25                  30

 Tyr Glu Trp Gly Val Arg Ser Thr Arg Lys Ser Glu Pro Pro Pro
                  35                  40                  45

 Leu Asp Arg Val Tyr Glu Ile Pro Gly Leu Glu Pro Ile Thr Phe
                  50                  55                  60

 Ala Gly Lys Met His Phe Val Pro Trp Leu Ala Arg Pro Ile Phe
                  65                  70                  75

 Pro Pro Trp Asp Arg Gly Tyr Lys Asp Pro Arg Phe Tyr Arg Ser
                  80                  85                  90

 Pro Pro Leu His Glu His Pro Leu Tyr Lys Asp Gln Ala Cys Tyr
                  95                 100                 105

 Ile Phe His His Arg Cys Arg Leu Leu Glu Gly Val Lys Gln Ala
                 110                 115                 120

 Leu Trp Leu Thr Lys Thr Lys Leu Ile Glu Gly Leu Pro Glu Lys
                 125                 130                 135

 Val Leu Ser Leu Val Asp Asp Pro Arg Asn His Ile Glu Asn Gln
                 140                 145                 150

 Asp Glu Cys Val Leu Asn Val Ile Ser His Ala Arg Leu Trp Gln
                 155                 160                 165

 Thr Thr Glu Glu Ile Pro Lys Arg Glu Thr Tyr Cys Pro Val Ile
                 170                 175                 180

 Val Asp Asn Leu Ile Gln Leu Cys Lys Ser Gln Ile Leu Lys His
                 185                 190                 195

 Pro Ser Leu Ala Arg Arg Ile Cys Val Gln Asn Ser Thr Phe Ser
                 200                 205                 210

 Ala Thr Trp Asn Arg Glu Ser Leu Leu Leu Gln Val Arg Gly Ser
                 215                 220                 225

 Gly Gly Ala Arg Leu Ser Thr Lys Asp Pro Leu Pro Thr Ile Ala
                 230                 235                 240

 Ser Arg Glu Glu Ile Glu Ala Thr Lys Asn His Val Leu Glu Thr
                 245                 250                 255

 Phe Tyr Pro Ile Ser Pro Ile Ile Asp Leu His Glu Cys Asn Ile
                 260                 265                 270

 Tyr Asp Val Lys Asn Asp Thr Gly Phe Gln Glu Gly Tyr Pro Tyr
                 275                 280                 285

 Pro Tyr Pro His Thr Leu Tyr Leu Leu Asp Lys Ala Asn Leu Arg
                 290                 295                 300

 Pro His Arg Leu Gln Pro Asp Gln Leu Arg Ala Lys Met Ile Leu
                 305                 310                 315

 Phe Ala Phe Gly Ser Ala Leu Ala Gln Ala Arg Leu Leu Tyr Gly
                 320                 325                 330

 Asn Asp Ala Lys Val Leu Glu Gln Pro Val Val Val Gln Ser Val
                 335                 340                 345

 Gly Thr Asp Gly Arg Val Phe His Phe Leu Val Phe Gln Leu Asn
                 350                 355                 360

 Thr Thr Asp Leu Asp Cys Asn Glu Gly Val Lys Asn Leu Ala Trp
                 365                 370                 375

 Val Asp Ser Asp Gln Leu Leu Tyr Gln His Phe Trp Cys Leu Pro
                 380                 385                 390

 Val Ile Lys Lys Arg Val Val Val Glu Pro Val Gly Pro Val Gly
                 395                 400                 405

 Phe Lys Pro Glu Thr Phe Arg Lys Phe Leu Ala Leu Tyr Leu His
                 410                 415                 420

 Gly Ala Ala


<210> 3805
<211> 2165
<212> DNA
<213> Homo sapien

<400> 3805
 ggcggctgag aggcgggcgg gccgggggcg ccgggcgcgg ggccgccatg 50

 tggagcggcc gcagctcctt caccagcttg gtggtgggcg tgttcgtggt 100

 ctacgtggtg cacacctgct gggtcatgta cggcatcgtc tacacccgcc 150

 cgtgctccgg cgacgccaac tgcatccagc cctacctggc gcggcggccc 200

 aagctgcagc tgagcgtgta caccacgacg aggtcccacc tgggtgctga 250

 gaacaacatc gacctggtct tgaatgtgga agactttgat gtggagtcca 300

 aatttgaaag gacagttaat gtttctgtac caaagaaaac gagaaacaat 350

 gggacgctgt atgcctacat cttcctccat cacgctgggg tcctgccgtg 400

 gcacgacggg aagcaggtgc acctggtcag tcctctgacc acctacatgg 450

 tccccaagcc agaagaaatc aacctgctca ccggggagtc tgatacacag 500

 cagatcgagg cggagaagaa gccgacgagt gccctggatg agccagtgtc 550

 ccactggcga ccgcggctgg cgctgaacgt gatggcggac aactttgtct 600

 ttgacgggtc ctccctgcct gccgatgtgc atcggtacat gaagatgatc 650

 cagctgggga aaaccgtgca ttacctgccc atcctgttca tcgaccagct 700

 cagcaaccgc gtgaaggacc tgatggtcat aaaccgctcc accaccgagc 750

 tgcccctcac cgtgtcctac gacaaggtct cactggggcg gctgcgcttc 800

 tggatccaca tgcaggacgc cgtgtactcc ctgcagcagt tcgggttttc 850

 agagaaagat gctgatgagg tgaaaggaat ttttgtagat accaacttat 900

 acttcctggc gctgaccttc tttgtcgcag cgttccatct tctctttgat 950

 ttcctggcct ttaaaaatga catcagtttc tggaagaaga agaagagcat 1000

 gatcggcatg tccaccaagg cagtgctctg gcgctgcttc agcaccgtgg 1050

 tcatctttct gttcctgctg gacgagcaga cgagcctgct ggtgctggtc 1100

 ccggcgggtg ttggagccgc cattgagctg tggaaagtga agaaggcatt 1150

 gaagatgact attttttgga gaggcctgat gcccgaattt cagtttggca 1200

 cttacagcga atctgagagg aaaaccgagg agtacgatac tcaggccatg 1250

 aagtacttgt catacctgct gtaccctctc tgtgtcgggg gtgctgtcta 1300

 ttcactcctg aatatcaaat ataagagctg gtactcctgg ttaatcaaca 1350

 gcttcgtcaa cggggtctat gcctttggtt tcctcttcat gctgccccag 1400

 ctctttgtga actacaagtt gaagtcagtg gcacatctgc cctggaaggc 1450

 cttcacctac aaggctttca acaccttcat tgatgacgtc tttgccttca 1500

 tcatcaccat gcccacgtct caccggctgg cctgcttccg ggacgacgtg 1550

 gtgtttctgg tctacctgta ccagcggtgg ctttatcctg tggataaacg 1600

 cagagtgaac gagtttgggg agtcctacga ggagaaggcc acgcgggcgc 1650

 cccacacgga ctgaaggccg cccgggctgc cgccagccaa gtgcaacttg 1700

 aattgtcaat gagtattttt ggaagcattt ggaggaattc ctagacattg 1750

 cgttttctgt gttgccaaaa tcccttcgga catttctcag acatctccca 1800

 agttcccatc acgtcagatt tggagctggt agcgcttacg atgcccccac 1850

 gtgtgaacat ctgtcttggt cacagagctg ggtgctgccg gtcaccttga 1900

 gctgtggtgg ctcccggcac acgagtgtcc ggggttcggc catgtcctca 1950

 cgcgggcagg ggtgggagcc ctcacaggca agggggctgt tggatttcca 2000

 tttcaggtgg ttttctaagt gctccttatg tgaatttcaa acacgtatgg 2050

 aattcattcc gcatggactc tgggatcaaa ggctctttcc tcttttgttt 2100

 gagagttggt tgttttaaag cttaatgtat gtttctattt taaaataaaa 2150

 aaaaaaaaaa aaaaa 2165

<210> 3806
<211> 538
<212> PRT
<213> Homo sapien

<400> 3806
 Met Trp Ser Gly Arg Ser Ser Phe Thr Ser Leu Val Val Gly Val
   1               5                  10                  15

 Phe Val Val Tyr Val Val His Thr Cys Trp Val Met Tyr Gly Ile
                  20                  25                  30

 Val Tyr Thr Arg Pro Cys Ser Gly Asp Ala Asn Cys Ile Gln Pro
                  35                  40                  45

 Tyr Leu Ala Arg Arg Pro Lys Leu Gln Leu Ser Val Tyr Thr Thr
                  50                  55                  60

 Thr Arg Ser His Leu Gly Ala Glu Asn Asn Ile Asp Leu Val Leu
                  65                  70                  75

 Asn Val Glu Asp Phe Asp Val Glu Ser Lys Phe Glu Arg Thr Val
                  80                  85                  90

 Asn Val Ser Val Pro Lys Lys Thr Arg Asn Asn Gly Thr Leu Tyr
                  95                 100                 105

 Ala Tyr Ile Phe Leu His His Ala Gly Val Leu Pro Trp His Asp
                 110                 115                 120

 Gly Lys Gln Val His Leu Val Ser Pro Leu Thr Thr Tyr Met Val
                 125                 130                 135

 Pro Lys Pro Glu Glu Ile Asn Leu Leu Thr Gly Glu Ser Asp Thr
                 140                 145                 150

 Gln Gln Ile Glu Ala Glu Lys Lys Pro Thr Ser Ala Leu Asp Glu
                 155                 160                 165

 Pro Val Ser His Trp Arg Pro Arg Leu Ala Leu Asn Val Met Ala
                 170                 175                 180

 Asp Asn Phe Val Phe Asp Gly Ser Ser Leu Pro Ala Asp Val His
                 185                 190                 195

 Arg Tyr Met Lys Met Ile Gln Leu Gly Lys Thr Val His Tyr Leu
                 200                 205                 210

 Pro Ile Leu Phe Ile Asp Gln Leu Ser Asn Arg Val Lys Asp Leu
                 215                 220                 225

 Met Val Ile Asn Arg Ser Thr Thr Glu Leu Pro Leu Thr Val Ser
                 230                 235                 240

 Tyr Asp Lys Val Ser Leu Gly Arg Leu Arg Phe Trp Ile His Met
                 245                 250                 255

 Gln Asp Ala Val Tyr Ser Leu Gln Gln Phe Gly Phe Ser Glu Lys
                 260                 265                 270

 Asp Ala Asp Glu Val Lys Gly Ile Phe Val Asp Thr Asn Leu Tyr
                 275                 280                 285

 Phe Leu Ala Leu Thr Phe Phe Val Ala Ala Phe His Leu Leu Phe
                 290                 295                 300

 Asp Phe Leu Ala Phe Lys Asn Asp Ile Ser Phe Trp Lys Lys Lys
                 305                 310                 315

 Lys Ser Met Ile Gly Met Ser Thr Lys Ala Val Leu Trp Arg Cys
                 320                 325                 330

 Phe Ser Thr Val Val Ile Phe Leu Phe Leu Leu Asp Glu Gln Thr
                 335                 340                 345

 Ser Leu Leu Val Leu Val Pro Ala Gly Val Gly Ala Ala Ile Glu
                 350                 355                 360

 Leu Trp Lys Val Lys Lys Ala Leu Lys Met Thr Ile Phe Trp Arg
                 365                 370                 375

 Gly Leu Met Pro Glu Phe Gln Phe Gly Thr Tyr Ser Glu Ser Glu
                 380                 385                 390

 Arg Lys Thr Glu Glu Tyr Asp Thr Gln Ala Met Lys Tyr Leu Ser
                 395                 400                 405

 Tyr Leu Leu Tyr Pro Leu Cys Val Gly Gly Ala Val Tyr Ser Leu
                 410                 415                 420

 Leu Asn Ile Lys Tyr Lys Ser Trp Tyr Ser Trp Leu Ile Asn Ser
                 425                 430                 435

 Phe Val Asn Gly Val Tyr Ala Phe Gly Phe Leu Phe Met Leu Pro
                 440                 445                 450

 Gln Leu Phe Val Asn Tyr Lys Leu Lys Ser Val Ala His Leu Pro
                 455                 460                 465

 Trp Lys Ala Phe Thr Tyr Lys Ala Phe Asn Thr Phe Ile Asp Asp
                 470                 475                 480

 Val Phe Ala Phe Ile Ile Thr Met Pro Thr Ser His Arg Leu Ala
                 485                 490                 495

 Cys Phe Arg Asp Asp Val Val Phe Leu Val Tyr Leu Tyr Gln Arg
                 500                 505                 510

 Trp Leu Tyr Pro Val Asp Lys Arg Arg Val Asn Glu Phe Gly Glu
                 515                 520                 525

 Ser Tyr Glu Glu Lys Ala Thr Arg Ala Pro His Thr Asp
                 530                 535

<210> 3807
<211> 4200
<212> DNA
<213> Homo sapien

<400> 3807
 ccagcggctg ggcctgagcg tcgagactcg gggccgaggc ggaggagcgg 50

 ccgccgcgcc ggggcccagc cggagccgcc gccctcgccc ttgcctttgc 100

 ctgcgcggct cagaatcacc atccgcggcg cgggagacga gccggccgtc 150

 ccgggccggg ggacccgccc gccatggcca ccaaggctcg ggttatgtat 200

 gattttgctg ctgaacctgg aaataatgaa ctgacggtta atgaaggaga 250

 aatcatcaca atcacaaatc cggatgtagg tggaggatgg ctggaaggaa 300

 gaaacatcaa aggagaacga gggctggttc ccacagacta cgttgaaatt 350

 ttacccagtg atggaaaaga tcaattttct tgtggaaatt cagtggctga 400

 ccaagccttc cttgattctc tctcagccag cacagctcag gccagttcgt 450

 cggctgccag caacaatcac caggttggca gtggcaatga cccctggtca 500

 gcctggagtg cctccaaatc tgggaactgg gaaagctcag aaggctgggg 550

 ggcccagcca gagggggctg gagcccaaag aaacacaaac actcccaaca 600

 actgggacac tgccttcggc cacccccagg cctaccaagg accagcaact 650

 ggtgatgatg atgactggga tgaagactgg gatgggccca aatcctcttc 700

 ctactttaag gattcagagt cagctgatgc aggcggcgct cagcgaggaa 750

 acagtcgtgc tagttcctca tccatgaaaa ttccccttaa caaatttcct 800

 ggatttgcga aacctggcac ggaacagtat ttgttggcca aacaactagc 850

 aaaacccaaa gagaaaattc ccatcattgt tggagattat ggcccaatgt 900

 gggtttatcc tacctctact tttgactgtg tggtagcaga tcccaggaaa 950

 ggctccaaaa tgtatggtct aaagagctac atcgaatatc agctaacacc 1000

 tactaacact aatcgatctg taaaccacag gtataagcac tttgactggt 1050

 tatatgagcg tctcctggtt aagtttgggt cagccattcc aatcccttct 1100

 cttccagaca aacaagtcac aggccgcttt gaagaggaat ttatcaaaat 1150

 gcgcatggag agacttcagg cctggatgac caggatgtgt cgccatccag 1200

 taatctcaga aagtgaagtt ttccagcagt tcctaaattt ccgagatgag 1250

 aaggaatgga aaactggaaa gaggaaggcc gagagagatg agctggcggg 1300

 agtcatgata ttttccacca tggaaccaga ggcacctgac ttggacttag 1350

 tagaaataga gcagaagtgc gaggctgtgg ggaagttcac caaggccatg 1400

 gatgacggcg tgaaggagct gctgacggtg gggcaggagc actggaagcg 1450

 ctgcacgggc ccattaccca aggaatatca gaagatagga aaggccttgc 1500

 agagtttggc cacagtgttc agttccagtg gctatcaagg tgaaacagat 1550

 ctcaatgatg caataacaga agcaggaaag acttatgaag aaattgccag 1600

 tctcgtggca gaacagccaa agaaagatct ccatttcctg atggaatgta 1650

 atcacgagta taaaggtttt cttggctgct tccctgacat cattggcact 1700

 cacaagggag caatagaaaa agtgaaagaa agtgacaaac tagttgcaac 1750

 aagtaaaatc accctacaag acaaacagaa catggtgaag agagtcagca 1800

 tcatgtctta cgcgttgcaa gctgagatga atcactttca cagtaaccgg 1850

 atctatgatt acaacagtgt catccgcctg tacctggagc agcaagtgca 1900

 attttacgaa acgattgcag aaaagctgag gcaggccctc agccgctttc 1950

 cagtgatgta ggacagaacg ggccttgaag agaatgccgc gtgctttctc 2000

 ctgacttggg gcaatgcaat tcaaaacttt ttttccccta ttattcagaa 2050

 aaaaaaggaa acaaaaccaa aaagaaagag ttgcaaaaaa ctgcatttat 2100

 tttattagcc accctaaatg cgtcagttat ttagggatgg tcttttgttc 2150

 atttccgcat ccattattta aaccagtgga aattgtctct atttttggaa 2200

 agtacttaaa agttaccaga attttcaatg gaaaatgagg ggtttctccc 2250

 cactgatatt ttacatagag tcataattta tatgtcttat aaattataag 2300

 tcttatataa tttataagtc tcccacaatc ttccagttct tacccagtgt 2350

 cagataatta attactaatt actttcttaa aaacatgaac tatgccagaa 2400

 taaaaaatat ctatgtttgt atatttttat aactcctttc agtcctctgg 2450

 ggctcctgtc attgagggaa gtcgttacgc ctttcactgc cacagttaca 2500

 gctcaagtgc ttacacttca agagggagga cgctgggggc ccctggggct 2550

 gctagtgcca tcgtggtgtg tggcaggtgg gccatcccat gtccctccag 2600

 ggggacccca cagcctggca gatgagcaga tacccctggc cacccatgtc 2650

 ctcagcgaca tttctgatgt gctgctctta tgtgaggacc agtgctttct 2700

 ctctttgcac ttccttccta atcttggtta aggcatgttt tatgccatga 2750

 agaatacatt agaagaattg agggactttg tagagaattt tgtggctttg 2800

 gtccaacggg tgagtggctg tgcggaggcc tgtgttcggg agggcctggg 2850

 agaaggaggg cacccagcac cccggcgtct ctggcccttt cttattcttt 2900

 ggctcctcat ccaccgtgat gagaagcgct gctgtggcca cggcacactg 2950

 cttggcttgg gtggcgggtt catggccagt tggtgtcatc agcaaagaga 3000

 aaaagcacag gttagctccc cattagatgg aaaagtgtag ggactgagaa 3050

 gggctgcagc ctcagcagtg tacagagtcc ccggcgctct gaggttggag 3100

 agaaagaaca gaccagcgcc cttcccgact acatccgaaa cttcacacag 3150

 ggtgtttctg agcaccagca cttccagcgc ttcacttaac ggcataaagc 3200

 aaaacaggac cttggcacac cgtcagctcg aactcaacac tggcagccac 3250

 cgtctcaccc ctgcggagga gcgctcccgt ctcccacagg tgccttaccg 3300

 cgttccctcc cgctgctttc atttttctga cctaataatt acgggaaatg 3350

 gaaagtctgg gccagcatca ataaaatgac accaaaaata agtagatgaa 3400

 atcaaatgaa tatgagaaca tcttgttctt caatatcacg ggtttttgtt 3450

 aatgtttcat aagtaattct ccccacttga tttttcttct ataaaatccc 3500

 atagaacaat gtttatgcta tagccattta atatatgtac aaattgtaaa 3550

 gaatatgtat aaatgtttta cacgaatgta agagcatgta gaagccaaca 3600

 tataaataaa ttgtttaaaa aaactgtaca gtaaattctc aaagcacttt 3650

 ttcaaaacac tttttggact ttgtgtgtga tttttgttgt tgttgttaag 3700

 tactttttat tccagctgct gaaaatggtc caggtaatga attcttcccc 3750

 aaatcctatt tcttctgaca tgaattcatc atttcagttc cgtaggtcag 3800

 tgttgcggtc cgggaagcgt atcataacca cctgggagtt gccaagaagc 3850

 agacagtctc ccagtgtctg actctcggat atttggattt gactggtgtg 3900

 aggcaaagtg aaaaagggat gggggaaatg gagatggcac gggctcctca 3950

 gagcgtggta gccgactgtg aggaaaagca gagggaatgt gaaagaaaat 4000

 aagagaatcc acgggatttg atgcctggaa gattctcctt caagtggcaa 4050

 catggcatat atatccttct ccggggagtc acatgcacca tttggttctt 4100

 agatacgttg atgttttgat ttttaatgat ttgtatcaac ctgtaggtac 4150

 cacagaagag ctgtagtcat acaatcacat aacttttaca aatatagtgg 4200

<210> 3808
<211> 595
<212> PRT
<213> Homo sapien

<400> 3808
 Met Ala Thr Lys Ala Arg Val Met Tyr Asp Phe Ala Ala Glu Pro
   1               5                  10                  15

 Gly Asn Asn Glu Leu Thr Val Asn Glu Gly Glu Ile Ile Thr Ile
                  20                  25                  30

 Thr Asn Pro Asp Val Gly Gly Gly Trp Leu Glu Gly Arg Asn Ile
                  35                  40                  45

 Lys Gly Glu Arg Gly Leu Val Pro Thr Asp Tyr Val Glu Ile Leu
                  50                  55                  60

 Pro Ser Asp Gly Lys Asp Gln Phe Ser Cys Gly Asn Ser Val Ala
                  65                  70                  75

 Asp Gln Ala Phe Leu Asp Ser Leu Ser Ala Ser Thr Ala Gln Ala
                  80                  85                  90

 Ser Ser Ser Ala Ala Ser Asn Asn His Gln Val Gly Ser Gly Asn
                  95                 100                 105

 Asp Pro Trp Ser Ala Trp Ser Ala Ser Lys Ser Gly Asn Trp Glu
                 110                 115                 120

 Ser Ser Glu Gly Trp Gly Ala Gln Pro Glu Gly Ala Gly Ala Gln
                 125                 130                 135

 Arg Asn Thr Asn Thr Pro Asn Asn Trp Asp Thr Ala Phe Gly His
                 140                 145                 150

 Pro Gln Ala Tyr Gln Gly Pro Ala Thr Gly Asp Asp Asp Asp Trp
                 155                 160                 165

 Asp Glu Asp Trp Asp Gly Pro Lys Ser Ser Ser Tyr Phe Lys Asp
                 170                 175                 180

 Ser Glu Ser Ala Asp Ala Gly Gly Ala Gln Arg Gly Asn Ser Arg
                 185                 190                 195

 Ala Ser Ser Ser Ser Met Lys Ile Pro Leu Asn Lys Phe Pro Gly
                 200                 205                 210

 Phe Ala Lys Pro Gly Thr Glu Gln Tyr Leu Leu Ala Lys Gln Leu
                 215                 220                 225

 Ala Lys Pro Lys Glu Lys Ile Pro Ile Ile Val Gly Asp Tyr Gly
                 230                 235                 240

 Pro Met Trp Val Tyr Pro Thr Ser Thr Phe Asp Cys Val Val Ala
                 245                 250                 255

 Asp Pro Arg Lys Gly Ser Lys Met Tyr Gly Leu Lys Ser Tyr Ile
                 260                 265                 270

 Glu Tyr Gln Leu Thr Pro Thr Asn Thr Asn Arg Ser Val Asn His
                 275                 280                 285

 Arg Tyr Lys His Phe Asp Trp Leu Tyr Glu Arg Leu Leu Val Lys
                 290                 295                 300

 Phe Gly Ser Ala Ile Pro Ile Pro Ser Leu Pro Asp Lys Gln Val
                 305                 310                 315

 Thr Gly Arg Phe Glu Glu Glu Phe Ile Lys Met Arg Met Glu Arg
                 320                 325                 330

 Leu Gln Ala Trp Met Thr Arg Met Cys Arg His Pro Val Ile Ser
                 335                 340                 345

 Glu Ser Glu Val Phe Gln Gln Phe Leu Asn Phe Arg Asp Glu Lys
                 350                 355                 360

 Glu Trp Lys Thr Gly Lys Arg Lys Ala Glu Arg Asp Glu Leu Ala
                 365                 370                 375

 Gly Val Met Ile Phe Ser Thr Met Glu Pro Glu Ala Pro Asp Leu
                 380                 385                 390

 Asp Leu Val Glu Ile Glu Gln Lys Cys Glu Ala Val Gly Lys Phe
                 395                 400                 405

 Thr Lys Ala Met Asp Asp Gly Val Lys Glu Leu Leu Thr Val Gly
                 410                 415                 420

 Gln Glu His Trp Lys Arg Cys Thr Gly Pro Leu Pro Lys Glu Tyr
                 425                 430                 435

 Gln Lys Ile Gly Lys Ala Leu Gln Ser Leu Ala Thr Val Phe Ser
                 440                 445                 450

 Ser Ser Gly Tyr Gln Gly Glu Thr Asp Leu Asn Asp Ala Ile Thr
                 455                 460                 465

 Glu Ala Gly Lys Thr Tyr Glu Glu Ile Ala Ser Leu Val Ala Glu
                 470                 475                 480

 Gln Pro Lys Lys Asp Leu His Phe Leu Met Glu Cys Asn His Glu
                 485                 490                 495

 Tyr Lys Gly Phe Leu Gly Cys Phe Pro Asp Ile Ile Gly Thr His
                 500                 505                 510

 Lys Gly Ala Ile Glu Lys Val Lys Glu Ser Asp Lys Leu Val Ala
                 515                 520                 525

 Thr Ser Lys Ile Thr Leu Gln Asp Lys Gln Asn Met Val Lys Arg
                 530                 535                 540

 Val Ser Ile Met Ser Tyr Ala Leu Gln Ala Glu Met Asn His Phe
                 545                 550                 555

 His Ser Asn Arg Ile Tyr Asp Tyr Asn Ser Val Ile Arg Leu Tyr
                 560                 565                 570

 Leu Glu Gln Gln Val Gln Phe Tyr Glu Thr Ile Ala Glu Lys Leu
                 575                 580                 585

 Arg Gln Ala Leu Ser Arg Phe Pro Val Met
                 590                 595

<210> 3809
<211> 4200
<212> DNA
<213> Homo sapien

<400> 3809
 ccagcggctg ggcctgagcg tcgagactcg gggccgaggc ggaggagcgg 50

 ccgccgcgcc ggggcccagc cggagccgcc gccctcgccc ttgcctttgc 100

 ctgcgcggct cagaatcacc atccgcggcg cgggagacga gccggccgtc 150

 ccgggccggg ggacccgccc gccatggcca ccaaggctcg ggttatgtat 200

 gattttgctg ctgaacctgg aaataatgaa ctgacggtta atgaaggaga 250

 aatcatcaca atcacaaatc cggatgtagg tggaggatgg ctggaaggaa 300

 gaaacatcaa aggagaacga gggctggttc ccacagacta cgttgaaatt 350

 ttacccagtg atggaaaaga tcaattttct tgtggaaatt cagtggctga 400

 ccaagccttc cttgattctc tctcagccag cacagctcag gccagttcgt 450

 cggctgccag caacaatcac caggttggca gtggcaatga cccctggtca 500

 gcctggagtg cctccaaatc tgggaactgg gaaagctcag aaggctgggg 550

 ggcccagcca gagggggctg gagcccaaag aaacacaaac actcccaaca 600

 actgggacac tgccttcggc cacccccagg cctaccaagg accagcaact 650

 ggtgatgatg atgactggga tgaagactgg gatgggccca aatcctcttc 700

 ctactttaag gattcagagt cagctgatgc aggcggcgct cagcgaggaa 750

 acagtcgtgc tagttcctca tccatgaaaa ttccccttaa caaatttcct 800

 ggatttgcga aacctggcac ggaacagtat ttgttggcca aacaactagc 850

 aaaacccaaa gagaaaattc ccatcattgt tggagattat ggcccaatgt 900

 gggtttatcc tacctctact tttgactgtg tggtagcaga tcccaggaaa 950

 ggctccaaaa tgtatggtct aaagagctac atcgaatatc agctaacacc 1000

 tactaacact aatcgatctg taaaccacag gtataagcac tttgactggt 1050

 tatatgagcg tctcctggtt aagtttgggt cagccattcc aatcccttct 1100

 cttccagaca aacaagtcac aggccgcttt gaagaggaat ttatcaaaat 1150

 gcgcatggag agacttcagg cctggatgac caggatgtgt cgccatccag 1200

 taatctcaga aagtgaagtt ttccagcagt tcctaaattt ccgagatgag 1250

 aaggaatgga aaactggaaa gaggaaggcc gagagagatg agctggcggg 1300

 agtcatgata ttttccacca tggaaccaga ggcacctgac ttggacttag 1350

 tagaaataga gcagaagtgc gaggctgtgg ggaagttcac caaggccatg 1400

 gatgacggcg tgaaggagct gctgacggtg gggcaggagc actggaagcg 1450

 ctgcacgggc ccattaccca aggaatatca gaagatagga aaggccttgc 1500

 agagtttggc cacagtgttc agttccagtg gctatcaagg tgaaacagat 1550

 ctcaatgatg caataacaga agcaggaaag acttatgaag aaattgccag 1600

 tctcgtggca gaacagccaa agaaagatct ccatttcctg atggaatgta 1650

 atcacgagta taaaggtttt cttggctgct tccctgacat cattggcact 1700

 cacaagggag caatagaaaa agtgaaagaa agtgacaaac tagttgcaac 1750

 aagtaaaatc accctacaag acaaacagaa catggtgaag agagtcagca 1800

 tcatgtctta cgcgttgcaa gctgagatga atcactttca cagtaaccgg 1850

 atctatgatt acaacagtgt catccgcctg tacctggagc agcaagtgca 1900

 attttacgaa acgattgcag aaaagctgag gcaggccctc agccgctttc 1950

 cagtgatgta ggacagaacg ggccttgaag agaatgccgc gtgctttctc 2000

 ctgacttggg gcaatgcaat tcaaaacttt ttttccccta ttattcagaa 2050

 aaaaaaggaa acaaaaccaa aaagaaagag ttgcaaaaaa ctgcatttat 2100

 tttattagcc accctaaatg cgtcagttat ttagggatgg tcttttgttc 2150

 atttccgcat ccattattta aaccagtgga aattgtctct atttttggaa 2200

 agtacttaaa agttaccaga attttcaatg gaaaatgagg ggtttctccc 2250

 cactgatatt ttacatagag tcataattta tatgtcttat aaattataag 2300

 tcttatataa tttataagtc tcccacaatc ttccagttct tacccagtgt 2350

 cagataatta attactaatt actttcttaa aaacatgaac tatgccagaa 2400

 taaaaaatat ctatgtttgt atatttttat aactcctttc agtcctctgg 2450

 ggctcctgtc attgagggaa gtcgttacgc ctttcactgc cacagttaca 2500

 gctcaagtgc ttacacttca agagggagga cgctgggggc ccctggggct 2550

 gctagtgcca tcgtggtgtg tggcaggtgg gccatcccat gtccctccag 2600

 ggggacccca cagcctggca gatgagcaga tacccctggc cacccatgtc 2650

 ctcagcgaca tttctgatgt gctgctctta tgtgaggacc agtgctttct 2700

 ctctttgcac ttccttccta atcttggtta aggcatgttt tatgccatga 2750

 agaatacatt agaagaattg agggactttg tagagaattt tgtggctttg 2800

 gtccaacggg tgagtggctg tgcggaggcc tgtgttcggg agggcctggg 2850

 agaaggaggg cacccagcac cccggcgtct ctggcccttt cttattcttt 2900

 ggctcctcat ccaccgtgat gagaagcgct gctgtggcca cggcacactg 2950

 cttggcttgg gtggcgggtt catggccagt tggtgtcatc agcaaagaga 3000

 aaaagcacag gttagctccc cattagatgg aaaagtgtag ggactgagaa 3050

 gggctgcagc ctcagcagtg tacagagtcc ccggcgctct gaggttggag 3100

 agaaagaaca gaccagcgcc cttcccgact acatccgaaa cttcacacag 3150

 ggtgtttctg agcaccagca cttccagcgc ttcacttaac ggcataaagc 3200

 aaaacaggac cttggcacac cgtcagctcg aactcaacac tggcagccac 3250

 cgtctcaccc ctgcggagga gcgctcccgt ctcccacagg tgccttaccg 3300

 cgttccctcc cgctgctttc atttttctga cctaataatt acgggaaatg 3350

 gaaagtctgg gccagcatca ataaaatgac accaaaaata agtagatgaa 3400

 atcaaatgaa tatgagaaca tcttgttctt caatatcacg ggtttttgtt 3450

 aatgtttcat aagtaattct ccccacttga tttttcttct ataaaatccc 3500

 atagaacaat gtttatgcta tagccattta atatatgtac aaattgtaaa 3550

 gaatatgtat aaatgtttta cacgaatgta agagcatgta gaagccaaca 3600

 tataaataaa ttgtttaaaa aaactgtaca gtaaattctc aaagcacttt 3650

 ttcaaaacac tttttggact ttgtgtgtga tttttgttgt tgttgttaag 3700

 tactttttat tccagctgct gaaaatggtc caggtaatga attcttcccc 3750

 aaatcctatt tcttctgaca tgaattcatc atttcagttc cgtaggtcag 3800

 tgttgcggtc cgggaagcgt atcataacca cctgggagtt gccaagaagc 3850

 agacagtctc ccagtgtctg actctcggat atttggattt gactggtgtg 3900

 aggcaaagtg aaaaagggat gggggaaatg gagatggcac gggctcctca 3950

 gagcgtggta gccgactgtg aggaaaagca gagggaatgt gaaagaaaat 4000

 aagagaatcc acgggatttg atgcctggaa gattctcctt caagtggcaa 4050

 catggcatat atatccttct ccggggagtc acatgcacca tttggttctt 4100

 agatacgttg atgttttgat ttttaatgat ttgtatcaac ctgtaggtac 4150

 cacagaagag ctgtagtcat acaatcacat aacttttaca aatatagtgg 4200

<210> 3810
<211> 595
<212> PRT
<213> Homo sapien

<400> 3810
 Met Ala Thr Lys Ala Arg Val Met Tyr Asp Phe Ala Ala Glu Pro
   1               5                  10                  15

 Gly Asn Asn Glu Leu Thr Val Asn Glu Gly Glu Ile Ile Thr Ile
                  20                  25                  30

 Thr Asn Pro Asp Val Gly Gly Gly Trp Leu Glu Gly Arg Asn Ile
                  35                  40                  45

 Lys Gly Glu Arg Gly Leu Val Pro Thr Asp Tyr Val Glu Ile Leu
                  50                  55                  60

 Pro Ser Asp Gly Lys Asp Gln Phe Ser Cys Gly Asn Ser Val Ala
                  65                  70                  75

 Asp Gln Ala Phe Leu Asp Ser Leu Ser Ala Ser Thr Ala Gln Ala
                  80                  85                  90

 Ser Ser Ser Ala Ala Ser Asn Asn His Gln Val Gly Ser Gly Asn
                  95                 100                 105

 Asp Pro Trp Ser Ala Trp Ser Ala Ser Lys Ser Gly Asn Trp Glu
                 110                 115                 120

 Ser Ser Glu Gly Trp Gly Ala Gln Pro Glu Gly Ala Gly Ala Gln
                 125                 130                 135

 Arg Asn Thr Asn Thr Pro Asn Asn Trp Asp Thr Ala Phe Gly His
                 140                 145                 150

 Pro Gln Ala Tyr Gln Gly Pro Ala Thr Gly Asp Asp Asp Asp Trp
                 155                 160                 165

 Asp Glu Asp Trp Asp Gly Pro Lys Ser Ser Ser Tyr Phe Lys Asp
                 170                 175                 180

 Ser Glu Ser Ala Asp Ala Gly Gly Ala Gln Arg Gly Asn Ser Arg
                 185                 190                 195

 Ala Ser Ser Ser Ser Met Lys Ile Pro Leu Asn Lys Phe Pro Gly
                 200                 205                 210

 Phe Ala Lys Pro Gly Thr Glu Gln Tyr Leu Leu Ala Lys Gln Leu
                 215                 220                 225

 Ala Lys Pro Lys Glu Lys Ile Pro Ile Ile Val Gly Asp Tyr Gly
                 230                 235                 240

 Pro Met Trp Val Tyr Pro Thr Ser Thr Phe Asp Cys Val Val Ala
                 245                 250                 255

 Asp Pro Arg Lys Gly Ser Lys Met Tyr Gly Leu Lys Ser Tyr Ile
                 260                 265                 270

 Glu Tyr Gln Leu Thr Pro Thr Asn Thr Asn Arg Ser Val Asn His
                 275                 280                 285

 Arg Tyr Lys His Phe Asp Trp Leu Tyr Glu Arg Leu Leu Val Lys
                 290                 295                 300

 Phe Gly Ser Ala Ile Pro Ile Pro Ser Leu Pro Asp Lys Gln Val
                 305                 310                 315

 Thr Gly Arg Phe Glu Glu Glu Phe Ile Lys Met Arg Met Glu Arg
                 320                 325                 330

 Leu Gln Ala Trp Met Thr Arg Met Cys Arg His Pro Val Ile Ser
                 335                 340                 345

 Glu Ser Glu Val Phe Gln Gln Phe Leu Asn Phe Arg Asp Glu Lys
                 350                 355                 360

 Glu Trp Lys Thr Gly Lys Arg Lys Ala Glu Arg Asp Glu Leu Ala
                 365                 370                 375

 Gly Val Met Ile Phe Ser Thr Met Glu Pro Glu Ala Pro Asp Leu
                 380                 385                 390

 Asp Leu Val Glu Ile Glu Gln Lys Cys Glu Ala Val Gly Lys Phe
                 395                 400                 405

 Thr Lys Ala Met Asp Asp Gly Val Lys Glu Leu Leu Thr Val Gly
                 410                 415                 420

 Gln Glu His Trp Lys Arg Cys Thr Gly Pro Leu Pro Lys Glu Tyr
                 425                 430                 435

 Gln Lys Ile Gly Lys Ala Leu Gln Ser Leu Ala Thr Val Phe Ser
                 440                 445                 450

 Ser Ser Gly Tyr Gln Gly Glu Thr Asp Leu Asn Asp Ala Ile Thr
                 455                 460                 465

 Glu Ala Gly Lys Thr Tyr Glu Glu Ile Ala Ser Leu Val Ala Glu
                 470                 475                 480

 Gln Pro Lys Lys Asp Leu His Phe Leu Met Glu Cys Asn His Glu
                 485                 490                 495

 Tyr Lys Gly Phe Leu Gly Cys Phe Pro Asp Ile Ile Gly Thr His
                 500                 505                 510

 Lys Gly Ala Ile Glu Lys Val Lys Glu Ser Asp Lys Leu Val Ala
                 515                 520                 525

 Thr Ser Lys Ile Thr Leu Gln Asp Lys Gln Asn Met Val Lys Arg
                 530                 535                 540

 Val Ser Ile Met Ser Tyr Ala Leu Gln Ala Glu Met Asn His Phe
                 545                 550                 555

 His Ser Asn Arg Ile Tyr Asp Tyr Asn Ser Val Ile Arg Leu Tyr
                 560                 565                 570

 Leu Glu Gln Gln Val Gln Phe Tyr Glu Thr Ile Ala Glu Lys Leu
                 575                 580                 585

 Arg Gln Ala Leu Ser Arg Phe Pro Val Met
                 590                 595

<210> 3811
<211> 1217
<212> DNA
<213> Homo sapien

<400> 3811
 caactcatgg cggcggcggc ggcggcggca gctgcttggg cgcggtgcgg 50

 tggtgactga gctacgagcc tggcggcggg tgtgcgccga gccccggccc 100

 ggcccggccc tcgcgtgcct cccaggctcc gcacccctga tgctgcgcgg 150

 gtgctgagcc cgcttcggcc gggacgatgg tgaagtattt cctgggccag 200

 agcgtgctcc ggagttcctg ggaccaagtg ttcgccgcct tctggcagcg 250

 gtacccgaat ccctatagca aacatgtctt gacggaagac atagtacacc 300

 gggaggtgac ccctgaccag aaactgctgt cccggcgact cctgaccaag 350

 accaacagga tgccacgctg ggccgagcga ctatttcctg ccaatgttgc 400

 tcactcggtg tacgtcctgg aggactctat tgtggaccca cagaatcaga 450

 ccatgactac cttcacctgg aacatcaacc acgcccggct gatggtggtg 500

 gaggaacgat gtgtttactg tgtgaactct gacaacagtg gctggactga 550

 aatccgccgg gaagcctggg tctcctctag cttatttggt gtctccagag 600

 ctgtccagga atttggtctt gcccggttca aaagcaacgt gaccaagact 650

 atgaagggtt ttgaatatat cttggctaag ctgcaaggcg aggccccttc 700

 caaaacactt gttgagacag ccaaggaagc caaggagaag gcaaaggaga 750

 cggcactggc agctacagag aaggccaagg acctcgccag caaggcggcc 800

 accaagaagc agcagcagca gcaacagttt gtgtagccag tctaccacca 850

 ccacagcacc ccagacagct aggcttagcc cctctgccct cccttcattg 900

 tactttatca ttaaaaatca acttccagcc ctgtctgctg tctacgtggt 950

 gggttgtggg gatgcagttt ggcatctgca gtacaccaag cacatgattc 1000

 atgtctgagc caggtctgct tattctccca ttgggcagct gaggaccgag 1050

 gcacagaggt gcggtgactt gcccggggct ccaggtagcc tgcaggttaa 1100

 ctggcggtaa gtgctagact gtaagcccga caagggcagg gcttttggtt 1150

 ttgttctctg atgtgtctca gtatctagca cataatagac actcaataaa 1200

 tacttgttga attcaaa 1217

<210> 3812
<211> 219
<212> PRT
<213> Homo sapien

<400> 3812
 Met Val Lys Tyr Phe Leu Gly Gln Ser Val Leu Arg Ser Ser Trp
   1               5                  10                  15

 Asp Gln Val Phe Ala Ala Phe Trp Gln Arg Tyr Pro Asn Pro Tyr
                  20                  25                  30

 Ser Lys His Val Leu Thr Glu Asp Ile Val His Arg Glu Val Thr
                  35                  40                  45

 Pro Asp Gln Lys Leu Leu Ser Arg Arg Leu Leu Thr Lys Thr Asn
                  50                  55                  60

 Arg Met Pro Arg Trp Ala Glu Arg Leu Phe Pro Ala Asn Val Ala
                  65                  70                  75

 His Ser Val Tyr Val Leu Glu Asp Ser Ile Val Asp Pro Gln Asn
                  80                  85                  90

 Gln Thr Met Thr Thr Phe Thr Trp Asn Ile Asn His Ala Arg Leu
                  95                 100                 105

 Met Val Val Glu Glu Arg Cys Val Tyr Cys Val Asn Ser Asp Asn
                 110                 115                 120

 Ser Gly Trp Thr Glu Ile Arg Arg Glu Ala Trp Val Ser Ser Ser
                 125                 130                 135

 Leu Phe Gly Val Ser Arg Ala Val Gln Glu Phe Gly Leu Ala Arg
                 140                 145                 150

 Phe Lys Ser Asn Val Thr Lys Thr Met Lys Gly Phe Glu Tyr Ile
                 155                 160                 165

 Leu Ala Lys Leu Gln Gly Glu Ala Pro Ser Lys Thr Leu Val Glu
                 170                 175                 180

 Thr Ala Lys Glu Ala Lys Glu Lys Ala Lys Glu Thr Ala Leu Ala
                 185                 190                 195

 Ala Thr Glu Lys Ala Lys Asp Leu Ala Ser Lys Ala Ala Thr Lys
                 200                 205                 210

 Lys Gln Gln Gln Gln Gln Gln Phe Val
                 215

<210> 3813
<211> 5231
<212> DNA
<213> Homo sapien

<400> 3813
 agctgtcgtg cctcgtggtc ccgggactgc agtggtgtgc gctctcggcg 50

 cgtggcgcta ggcatggcga tggatcaagt aaacgcgctg tgcgagcagc 100

 tggtgaaagc ggtgacggtc atgatggacc ccaactccac ccagcgctac 150

 cggctggaag ccctcaagtt ttgtgaggag tttaaagaaa agtgtcctat 200

 ctgtgtcccc tgtggcttga ggttggctga gaaaacacaa gttgccatcg 250

 tcagacattt tggccttcag atcctggaac acgttgtcaa gtttcggtgg 300

 aacggcatgt ctcgattgga gaaggtgtat ctgaagaaca gtgtcatgga 350

 gctgattgca aatggaacat tgaacatttt ggaagaggag aaccatatta 400

 aagatgctct gtctcgaatt gtagtggaaa tgatcaagcg agagtggcca 450

 cagcattggc ctgacatgct aatagaattg gacactcttt ccaaacaagg 500

 ggaaacacag acagaattgg tgatgtttat ccttttgcga ctggcagagg 550

 atgtagtgac ttttcagaca cttccccctc aaagaagaag ggacatccag 600

 caaacattaa cccagaacat ggaaaggatc ttcagttttc tgcttaacac 650

 acttcaagaa aatgtaaaca agtatcagca agtgaagaca gatacttctc 700

 aggagtcaaa ggcgcaagca aactgtcgag taggagttgc agcactgaat 750

 actctagcag gctatattga ctgggtgtct atgagtcaca tcactgctga 800

 aaactgtaaa ctcctggaga tactgtgttt gctgttgaat gaacaggaac 850

 ttcagttggg agccgctgag tgtcttctca ttgcagtcag cagaaaaggc 900

 aagttggaag accggaagcc cttgatggtc ttatttggag atgttgccat 950

 gcattatata ctctccgccg cacagactgc tgatggagga ggtttggtag 1000

 aaaaacacta cgtctttctg aagaggctct gtcaggtgtt gtgtgcgctg 1050

 ggcaatcagc tgtgtgcatt gctgggtgca gattctgatg tagaaacacc 1100

 atcaaacttt ggaaaatacc tggaatcttt tcttgctttc acaacccatc 1150

 caagtcagtt tctacgctct tcaactcaga tgacttgggg agccctcttc 1200

 aggcatgaaa tcctgtcccg tgatcctttg ctattagcaa taataccaaa 1250

 atatcttcgt gcttccatga ctaacttggt caagatgggc tttccttcta 1300

 aaacagacag ccctagctgt gaatattctc ggtttgattt tgatagcgat 1350

 gaggacttca atgctttctt caactcctcc cgagcacaac aaggagaggt 1400

 gatgaggttg gcatgtcgtt tggatcccaa aactagcttc cagatggctg 1450

 gggagtggct aaagtatcaa ctatcaactt ttcttgatgc tggttctgtg 1500

 aattcttgtt ctgcagttgg aactggagaa ggaagcctct gttccgtctt 1550

 ctcaccttca ttcgtgcagt gggaagccat gactcttttt ttggaaagtg 1600

 ttatcaccca gatgtttcga acactaaata gagaagaaat tcctgttaat 1650

 gatggaatag agctattgca gatggttctg aactttgata ccaaggatcc 1700

 cctcatcctg tcctgcgtcc ttactaatgt ctctgcactc tttccatttg 1750

 tcacctacag accagagttc ctgccccagg tcttctctaa gctattttca 1800

 tctgtcactt ttgaaactgt tgaagaaagt aaggccccca gaacccgggc 1850

 agtgaggaat gtgaggaggc atgcttgttc ctccatcatc aagatgtgtc 1900

 gtgactaccc ccagcttgtg ctgcccaatt ttgacatgct ttataaccat 1950

 gtgaagcaac tcctctccaa tgagctactc ctgacacaaa tggagaagtg 2000

 tgccctcatg gaagccctgg ttctcattag caaccaattt aagaactacg 2050

 agcgtcagaa ggtgttccta gaggagctga tggcaccagt ggccagcatc 2100

 tggctttctc aagacatgca cagagtgctg tcagatgttg atgctttcat 2150

 tgcgtatgtg ggtacagatc agaagagctg tgacccaggc ctggaggatc 2200

 cgtgtggctt aaaccgtgca cgaatgagct tttgtgtata cagcattctg 2250

 ggtgtggtga aacgaacttg ctggcccact gacctagaag aggccaaagc 2300

 tgggggattt gtggtgggtt atacatccag tggaaatcca atcttccgta 2350

 acccctgcac agagcagatt ctgaaacttc ttgacaattt gcttgcgctt 2400

 ataagaaccc acaatacatt atatgcacca gaaatgctag ccaaaatggc 2450

 agagcctttc accaaggctc tggatatgct tgacgcggaa aaatctgcta 2500

 tattaggatt acctcaacct ctcttggaac tcaatgactc tcctgtcttc 2550

 aaaaccgtct tggaaagaat gcagcgtttc ttctctaccc tctatgaaaa 2600

 ctgttttcat atcctaggga aggcaggccc ttccatgcag caagacttct 2650

 atactgtgga ggaccttgct acccagcttc tcagctcagc ctttgtcaac 2700

 ttgaacaata ttcctgacta ccgactcaga cccatgcttc gtgtctttgt 2750

 aaagcctctg gtgctcttct gtcccccaga gcactatgaa gccctggtat 2800

 cccccatcct cggacctctt ttcacctacc tccatatgag gctttctcag 2850

 aaatggcaag ttatcaacca aaggagcctg ctgtgtggag aagatgaggc 2900

 tgcagatgaa aacccagagt ctcaagagat gctggaggag caactggtga 2950

 ggatgttaac ccgagaagtc atggacctaa tcacggtttg ctgtgtttca 3000

 aagaagggtg ctgaccacag tagtgctccc ccagcagatg gagacgatga 3050

 agaaatgatg gccacagagg tcaccccctc agctatggca gagcttacag 3100

 acctgggcaa atgtctgatg aagcatgagg atgtttgtac agcgctatta 3150

 attacagcct tcaattccct ggcctggaaa gatactctgt cctgccagag 3200

 gacaacctca cagctctgct ggcctctcct caaacaagtg ctgtcaggga 3250

 cactgctcgc agatgcagtt acgtggcttt tcaccagtgt gctgaaaggc 3300

 ttacagatgc acgggcagca cgacgggtgc atggcttccc tggtccatct 3350

 ggccttccag atatatgagg cactgcgccc caggtacctg gagataagag 3400

 ctgtaatgga gcaaatccct gaaatacaga aggactcact ggaccagttt 3450

 gactgcaagc ttttaaaccc ctccctgcag aaagtggctg acaagcgccg 3500

 aaaggaccaa ttcaaacgcc tcattgctgg ttgcattggg aaacccttgg 3550

 gagagcagtt ccgaaaagaa gttcacatta agaatcttcc ctcacttttc 3600

 aaaaaaacaa agccaatgct ggagacggag gtgctggaca atgatggggg 3650

 tggcctggcc accatctttg aaccctgaat caagcttttg ggcatccttc 3700

 ctcggccttt cttgtcatct cttctttccc tttgtagccg atctctaggc 3750

 ccttcttgca ctgccacctc actttccacc actgtcagcc tggaaagaga 3800

 tccaggtctg gagctggaga gaacaggccc tgtgcaggac cagaagtaat 3850

 tatactaaag tatcaagaaa gggagttagg gcttaaacta ttctgtctag 3900

 atgtcccaga tagttcccat tctacttgga gatttggctt ttccaagaaa 3950

 agctagagca gagcagccct tctcccacaa gccctcccac ccccgtgcag 4000

 ccacatacct gtacagaatg gtaactaagg gtgctgtgcc caaccctgcg 4050

 actagcaagg ctcgcagcaa gagcacagcc ctcaactact tgtgccagag 4100

 tttctcttgg accactccaa ctcccactga gcccttttgc tgctgggctg 4150

 gcaggaaact ttccccactc cctaaggggc atgtctgggt taggtgctaa 4200

 gtgctgaaga gaacttggtc agttctctca actttgcttt gggcaagaat 4250

 ctggtcacct gatgggatcc atggtacagg ctactgctaa acttggcaca 4300

 gtatcaagta tagtacctcc aaggaccagg gctgggaagt ctttagtgct 4350

 aacatcccct ttagagttca cacatcttgc ccttccatga atgacccctc 4400

 agtctggcct ccccagcctc aaggtccact caggcacaag agccacagta 4450

 ccctagatag tgtcacatga caccgttgtc atccaaggat aatacagacc 4500

 aactaggcta catctgtgat gagcagctag caaagccgct ggtcttctcc 4550

 taggactaag tccaggtgcc ttccacaatc tcatggtctt tcaggtccct 4600

 ggttactttt ctcaaaggcc atttccaaaa gaatacatgc cttcacatca 4650

 caacctgtac tgtgagtcca ttctagaggt cactgaaagg ccctgtaaag 4700

 agaggacatg gatacgggac ctggccctga ggttattact ggccgtaagg 4750

 cagagttaat ccatacagaa accagtgtgt ccatgtgctc tgcacaaaaa 4800

 cagacctgtt gtccatccag tccactgaca agagggtttc cccgagagcc 4850

 gaagtggact gaagctacag tttttagctg gtgcgggcca caggcagggt 4900

 cagattgaga agaagcaaag ctggggaagc agaagttggg agtcttgtgt 4950

 tgctccctct tcctgtgtgg tgctctgggt ttctgtggat cgtgaaggcg 5000

 atctcaagag tgtttccctc caaacctgat agctgcctat tcctgtctgg 5050

 ttggggctgt ggaggatgta gttgtattta ttgcattgta atatttttaa 5100

 catcctgtga cttcatgcta gaaattttct attgtttata gaaacttttt 5150

 gtagaaacat taactctaaa gcacatctgc atgtcagtaa aaatctcagt 5200

 ttcgtacaga aaaaaaaaaa aaaaaaaaaa a 5231

<210> 3814
<211> 1204
<212> PRT
<213> Homo sapien

<400> 3814
 Met Ala Met Asp Gln Val Asn Ala Leu Cys Glu Gln Leu Val Lys
   1               5                  10                  15

 Ala Val Thr Val Met Met Asp Pro Asn Ser Thr Gln Arg Tyr Arg
                  20                  25                  30

 Leu Glu Ala Leu Lys Phe Cys Glu Glu Phe Lys Glu Lys Cys Pro
                  35                  40                  45

 Ile Cys Val Pro Cys Gly Leu Arg Leu Ala Glu Lys Thr Gln Val
                  50                  55                  60

 Ala Ile Val Arg His Phe Gly Leu Gln Ile Leu Glu His Val Val
                  65                  70                  75

 Lys Phe Arg Trp Asn Gly Met Ser Arg Leu Glu Lys Val Tyr Leu
                  80                  85                  90

 Lys Asn Ser Val Met Glu Leu Ile Ala Asn Gly Thr Leu Asn Ile
                  95                 100                 105

 Leu Glu Glu Glu Asn His Ile Lys Asp Ala Leu Ser Arg Ile Val
                 110                 115                 120

 Val Glu Met Ile Lys Arg Glu Trp Pro Gln His Trp Pro Asp Met
                 125                 130                 135

 Leu Ile Glu Leu Asp Thr Leu Ser Lys Gln Gly Glu Thr Gln Thr
                 140                 145                 150

 Glu Leu Val Met Phe Ile Leu Leu Arg Leu Ala Glu Asp Val Val
                 155                 160                 165

 Thr Phe Gln Thr Leu Pro Pro Gln Arg Arg Arg Asp Ile Gln Gln
                 170                 175                 180

 Thr Leu Thr Gln Asn Met Glu Arg Ile Phe Ser Phe Leu Leu Asn
                 185                 190                 195

 Thr Leu Gln Glu Asn Val Asn Lys Tyr Gln Gln Val Lys Thr Asp
                 200                 205                 210

 Thr Ser Gln Glu Ser Lys Ala Gln Ala Asn Cys Arg Val Gly Val
                 215                 220                 225

 Ala Ala Leu Asn Thr Leu Ala Gly Tyr Ile Asp Trp Val Ser Met
                 230                 235                 240

 Ser His Ile Thr Ala Glu Asn Cys Lys Leu Leu Glu Ile Leu Cys
                 245                 250                 255

 Leu Leu Leu Asn Glu Gln Glu Leu Gln Leu Gly Ala Ala Glu Cys
                 260                 265                 270

 Leu Leu Ile Ala Val Ser Arg Lys Gly Lys Leu Glu Asp Arg Lys
                 275                 280                 285

 Pro Leu Met Val Leu Phe Gly Asp Val Ala Met His Tyr Ile Leu
                 290                 295                 300

 Ser Ala Ala Gln Thr Ala Asp Gly Gly Gly Leu Val Glu Lys His
                 305                 310                 315

 Tyr Val Phe Leu Lys Arg Leu Cys Gln Val Leu Cys Ala Leu Gly
                 320                 325                 330

 Asn Gln Leu Cys Ala Leu Leu Gly Ala Asp Ser Asp Val Glu Thr
                 335                 340                 345

 Pro Ser Asn Phe Gly Lys Tyr Leu Glu Ser Phe Leu Ala Phe Thr
                 350                 355                 360

 Thr His Pro Ser Gln Phe Leu Arg Ser Ser Thr Gln Met Thr Trp
                 365                 370                 375

 Gly Ala Leu Phe Arg His Glu Ile Leu Ser Arg Asp Pro Leu Leu
                 380                 385                 390

 Leu Ala Ile Ile Pro Lys Tyr Leu Arg Ala Ser Met Thr Asn Leu
                 395                 400                 405

 Val Lys Met Gly Phe Pro Ser Lys Thr Asp Ser Pro Ser Cys Glu
                 410                 415                 420

 Tyr Ser Arg Phe Asp Phe Asp Ser Asp Glu Asp Phe Asn Ala Phe
                 425                 430                 435

 Phe Asn Ser Ser Arg Ala Gln Gln Gly Glu Val Met Arg Leu Ala
                 440                 445                 450

 Cys Arg Leu Asp Pro Lys Thr Ser Phe Gln Met Ala Gly Glu Trp
                 455                 460                 465

 Leu Lys Tyr Gln Leu Ser Thr Phe Leu Asp Ala Gly Ser Val Asn
                 470                 475                 480

 Ser Cys Ser Ala Val Gly Thr Gly Glu Gly Ser Leu Cys Ser Val
                 485                 490                 495

 Phe Ser Pro Ser Phe Val Gln Trp Glu Ala Met Thr Leu Phe Leu
                 500                 505                 510

 Glu Ser Val Ile Thr Gln Met Phe Arg Thr Leu Asn Arg Glu Glu
                 515                 520                 525

 Ile Pro Val Asn Asp Gly Ile Glu Leu Leu Gln Met Val Leu Asn
                 530                 535                 540

 Phe Asp Thr Lys Asp Pro Leu Ile Leu Ser Cys Val Leu Thr Asn
                 545                 550                 555

 Val Ser Ala Leu Phe Pro Phe Val Thr Tyr Arg Pro Glu Phe Leu
                 560                 565                 570

 Pro Gln Val Phe Ser Lys Leu Phe Ser Ser Val Thr Phe Glu Thr
                 575                 580                 585

 Val Glu Glu Ser Lys Ala Pro Arg Thr Arg Ala Val Arg Asn Val
                 590                 595                 600

 Arg Arg His Ala Cys Ser Ser Ile Ile Lys Met Cys Arg Asp Tyr
                 605                 610                 615

 Pro Gln Leu Val Leu Pro Asn Phe Asp Met Leu Tyr Asn His Val
                 620                 625                 630

 Lys Gln Leu Leu Ser Asn Glu Leu Leu Leu Thr Gln Met Glu Lys
                 635                 640                 645

 Cys Ala Leu Met Glu Ala Leu Val Leu Ile Ser Asn Gln Phe Lys
                 650                 655                 660

 Asn Tyr Glu Arg Gln Lys Val Phe Leu Glu Glu Leu Met Ala Pro
                 665                 670                 675

 Val Ala Ser Ile Trp Leu Ser Gln Asp Met His Arg Val Leu Ser
                 680                 685                 690

 Asp Val Asp Ala Phe Ile Ala Tyr Val Gly Thr Asp Gln Lys Ser
                 695                 700                 705

 Cys Asp Pro Gly Leu Glu Asp Pro Cys Gly Leu Asn Arg Ala Arg
                 710                 715                 720

 Met Ser Phe Cys Val Tyr Ser Ile Leu Gly Val Val Lys Arg Thr
                 725                 730                 735

 Cys Trp Pro Thr Asp Leu Glu Glu Ala Lys Ala Gly Gly Phe Val
                 740                 745                 750

 Val Gly Tyr Thr Ser Ser Gly Asn Pro Ile Phe Arg Asn Pro Cys
                 755                 760                 765

 Thr Glu Gln Ile Leu Lys Leu Leu Asp Asn Leu Leu Ala Leu Ile
                 770                 775                 780

 Arg Thr His Asn Thr Leu Tyr Ala Pro Glu Met Leu Ala Lys Met
                 785                 790                 795

 Ala Glu Pro Phe Thr Lys Ala Leu Asp Met Leu Asp Ala Glu Lys
                 800                 805                 810

 Ser Ala Ile Leu Gly Leu Pro Gln Pro Leu Leu Glu Leu Asn Asp
                 815                 820                 825

 Ser Pro Val Phe Lys Thr Val Leu Glu Arg Met Gln Arg Phe Phe
                 830                 835                 840

 Ser Thr Leu Tyr Glu Asn Cys Phe His Ile Leu Gly Lys Ala Gly
                 845                 850                 855

 Pro Ser Met Gln Gln Asp Phe Tyr Thr Val Glu Asp Leu Ala Thr
                 860                 865                 870

 Gln Leu Leu Ser Ser Ala Phe Val Asn Leu Asn Asn Ile Pro Asp
                 875                 880                 885

 Tyr Arg Leu Arg Pro Met Leu Arg Val Phe Val Lys Pro Leu Val
                 890                 895                 900

 Leu Phe Cys Pro Pro Glu His Tyr Glu Ala Leu Val Ser Pro Ile
                 905                 910                 915

 Leu Gly Pro Leu Phe Thr Tyr Leu His Met Arg Leu Ser Gln Lys
                 920                 925                 930

 Trp Gln Val Ile Asn Gln Arg Ser Leu Leu Cys Gly Glu Asp Glu
                 935                 940                 945

 Ala Ala Asp Glu Asn Pro Glu Ser Gln Glu Met Leu Glu Glu Gln
                 950                 955                 960

 Leu Val Arg Met Leu Thr Arg Glu Val Met Asp Leu Ile Thr Val
                 965                 970                 975

 Cys Cys Val Ser Lys Lys Gly Ala Asp His Ser Ser Ala Pro Pro
                 980                 985                 990

 Ala Asp Gly Asp Asp Glu Glu Met Met Ala Thr Glu Val Thr Pro
                 995                1000                1005

 Ser Ala Met Ala Glu Leu Thr Asp Leu Gly Lys Cys Leu Met Lys
                1010                1015                1020

 His Glu Asp Val Cys Thr Ala Leu Leu Ile Thr Ala Phe Asn Ser
                1025                1030                1035

 Leu Ala Trp Lys Asp Thr Leu Ser Cys Gln Arg Thr Thr Ser Gln
                1040                1045                1050

 Leu Cys Trp Pro Leu Leu Lys Gln Val Leu Ser Gly Thr Leu Leu
                1055                1060                1065

 Ala Asp Ala Val Thr Trp Leu Phe Thr Ser Val Leu Lys Gly Leu
                1070                1075                1080

 Gln Met His Gly Gln His Asp Gly Cys Met Ala Ser Leu Val His
                1085                1090                1095

 Leu Ala Phe Gln Ile Tyr Glu Ala Leu Arg Pro Arg Tyr Leu Glu
                1100                1105                1110

 Ile Arg Ala Val Met Glu Gln Ile Pro Glu Ile Gln Lys Asp Ser
                1115                1120                1125

 Leu Asp Gln Phe Asp Cys Lys Leu Leu Asn Pro Ser Leu Gln Lys
                1130                1135                1140

 Val Ala Asp Lys Arg Arg Lys Asp Gln Phe Lys Arg Leu Ile Ala
                1145                1150                1155

 Gly Cys Ile Gly Lys Pro Leu Gly Glu Gln Phe Arg Lys Glu Val
                1160                1165                1170

 His Ile Lys Asn Leu Pro Ser Leu Phe Lys Lys Thr Lys Pro Met
                1175                1180                1185

 Leu Glu Thr Glu Val Leu Asp Asn Asp Gly Gly Gly Leu Ala Thr
                1190                1195                1200

 Ile Phe Glu Pro


<210> 3815
<211> 5231
<212> DNA
<213> Homo sapien

<400> 3815
 agctgtcgtg cctcgtggtc ccgggactgc agtggtgtgc gctctcggcg 50

 cgtggcgcta ggcatggcga tggatcaagt aaacgcgctg tgcgagcagc 100

 tggtgaaagc ggtgacggtc atgatggacc ccaactccac ccagcgctac 150

 cggctggaag ccctcaagtt ttgtgaggag tttaaagaaa agtgtcctat 200

 ctgtgtcccc tgtggcttga ggttggctga gaaaacacaa gttgccatcg 250

 tcagacattt tggccttcag atcctggaac acgttgtcaa gtttcggtgg 300

 aacggcatgt ctcgattgga gaaggtgtat ctgaagaaca gtgtcatgga 350

 gctgattgca aatggaacat tgaacatttt ggaagaggag aaccatatta 400

 aagatgctct gtctcgaatt gtagtggaaa tgatcaagcg agagtggcca 450

 cagcattggc ctgacatgct aatagaattg gacactcttt ccaaacaagg 500

 ggaaacacag acagaattgg tgatgtttat ccttttgcga ctggcagagg 550

 atgtagtgac ttttcagaca cttccccctc aaagaagaag ggacatccag 600

 caaacattaa cccagaacat ggaaaggatc ttcagttttc tgcttaacac 650

 acttcaagaa aatgtaaaca agtatcagca agtgaagaca gatacttctc 700

 aggagtcaaa ggcgcaagca aactgtcgag taggagttgc agcactgaat 750

 actctagcag gctatattga ctgggtgtct atgagtcaca tcactgctga 800

 aaactgtaaa ctcctggaga tactgtgttt gctgttgaat gaacaggaac 850

 ttcagttggg agccgctgag tgtcttctca ttgcagtcag cagaaaaggc 900

 aagttggaag accggaagcc cttgatggtc ttatttggag atgttgccat 950

 gcattatata ctctccgccg cacagactgc tgatggagga ggtttggtag 1000

 aaaaacacta cgtctttctg aagaggctct gtcaggtgtt gtgtgcgctg 1050

 ggcaatcagc tgtgtgcatt gctgggtgca gattctgatg tagaaacacc 1100

 atcaaacttt ggaaaatacc tggaatcttt tcttgctttc acaacccatc 1150

 caagtcagtt tctacgctct tcaactcaga tgacttgggg agccctcttc 1200

 aggcatgaaa tcctgtcccg tgatcctttg ctattagcaa taataccaaa 1250

 atatcttcgt gcttccatga ctaacttggt caagatgggc tttccttcta 1300

 aaacagacag ccctagctgt gaatattctc ggtttgattt tgatagcgat 1350

 gaggacttca atgctttctt caactcctcc cgagcacaac aaggagaggt 1400

 gatgaggttg gcatgtcgtt tggatcccaa aactagcttc cagatggctg 1450

 gggagtggct aaagtatcaa ctatcaactt ttcttgatgc tggttctgtg 1500

 aattcttgtt ctgcagttgg aactggagaa ggaagcctct gttccgtctt 1550

 ctcaccttca ttcgtgcagt gggaagccat gactcttttt ttggaaagtg 1600

 ttatcaccca gatgtttcga acactaaata gagaagaaat tcctgttaat 1650

 gatggaatag agctattgca gatggttctg aactttgata ccaaggatcc 1700

 cctcatcctg tcctgcgtcc ttactaatgt ctctgcactc tttccatttg 1750

 tcacctacag accagagttc ctgccccagg tcttctctaa gctattttca 1800

 tctgtcactt ttgaaactgt tgaagaaagt aaggccccca gaacccgggc 1850

 agtgaggaat gtgaggaggc atgcttgttc ctccatcatc aagatgtgtc 1900

 gtgactaccc ccagcttgtg ctgcccaatt ttgacatgct ttataaccat 1950

 gtgaagcaac tcctctccaa tgagctactc ctgacacaaa tggagaagtg 2000

 tgccctcatg gaagccctgg ttctcattag caaccaattt aagaactacg 2050

 agcgtcagaa ggtgttccta gaggagctga tggcaccagt ggccagcatc 2100

 tggctttctc aagacatgca cagagtgctg tcagatgttg atgctttcat 2150

 tgcgtatgtg ggtacagatc agaagagctg tgacccaggc ctggaggatc 2200

 cgtgtggctt aaaccgtgca cgaatgagct tttgtgtata cagcattctg 2250

 ggtgtggtga aacgaacttg ctggcccact gacctagaag aggccaaagc 2300

 tgggggattt gtggtgggtt atacatccag tggaaatcca atcttccgta 2350

 acccctgcac agagcagatt ctgaaacttc ttgacaattt gcttgcgctt 2400

 ataagaaccc acaatacatt atatgcacca gaaatgctag ccaaaatggc 2450

 agagcctttc accaaggctc tggatatgct tgacgcggaa aaatctgcta 2500

 tattaggatt acctcaacct ctcttggaac tcaatgactc tcctgtcttc 2550

 aaaaccgtct tggaaagaat gcagcgtttc ttctctaccc tctatgaaaa 2600

 ctgttttcat atcctaggga aggcaggccc ttccatgcag caagacttct 2650

 atactgtgga ggaccttgct acccagcttc tcagctcagc ctttgtcaac 2700

 ttgaacaata ttcctgacta ccgactcaga cccatgcttc gtgtctttgt 2750

 aaagcctctg gtgctcttct gtcccccaga gcactatgaa gccctggtat 2800

 cccccatcct cggacctctt ttcacctacc tccatatgag gctttctcag 2850

 aaatggcaag ttatcaacca aaggagcctg ctgtgtggag aagatgaggc 2900

 tgcagatgaa aacccagagt ctcaagagat gctggaggag caactggtga 2950

 ggatgttaac ccgagaagtc atggacctaa tcacggtttg ctgtgtttca 3000

 aagaagggtg ctgaccacag tagtgctccc ccagcagatg gagacgatga 3050

 agaaatgatg gccacagagg tcaccccctc agctatggca gagcttacag 3100

 acctgggcaa atgtctgatg aagcatgagg atgtttgtac agcgctatta 3150

 attacagcct tcaattccct ggcctggaaa gatactctgt cctgccagag 3200

 gacaacctca cagctctgct ggcctctcct caaacaagtg ctgtcaggga 3250

 cactgctcgc agatgcagtt acgtggcttt tcaccagtgt gctgaaaggc 3300

 ttacagatgc acgggcagca cgacgggtgc atggcttccc tggtccatct 3350

 ggccttccag atatatgagg cactgcgccc caggtacctg gagataagag 3400

 ctgtaatgga gcaaatccct gaaatacaga aggactcact ggaccagttt 3450

 gactgcaagc ttttaaaccc ctccctgcag aaagtggctg acaagcgccg 3500

 aaaggaccaa ttcaaacgcc tcattgctgg ttgcattggg aaacccttgg 3550

 gagagcagtt ccgaaaagaa gttcacatta agaatcttcc ctcacttttc 3600

 aaaaaaacaa agccaatgct ggagacggag gtgctggaca atgatggggg 3650

 tggcctggcc accatctttg aaccctgaat caagcttttg ggcatccttc 3700

 ctcggccttt cttgtcatct cttctttccc tttgtagccg atctctaggc 3750

 ccttcttgca ctgccacctc actttccacc actgtcagcc tggaaagaga 3800

 tccaggtctg gagctggaga gaacaggccc tgtgcaggac cagaagtaat 3850

 tatactaaag tatcaagaaa gggagttagg gcttaaacta ttctgtctag 3900

 atgtcccaga tagttcccat tctacttgga gatttggctt ttccaagaaa 3950

 agctagagca gagcagccct tctcccacaa gccctcccac ccccgtgcag 4000

 ccacatacct gtacagaatg gtaactaagg gtgctgtgcc caaccctgcg 4050

 actagcaagg ctcgcagcaa gagcacagcc ctcaactact tgtgccagag 4100

 tttctcttgg accactccaa ctcccactga gcccttttgc tgctgggctg 4150

 gcaggaaact ttccccactc cctaaggggc atgtctgggt taggtgctaa 4200

 gtgctgaaga gaacttggtc agttctctca actttgcttt gggcaagaat 4250

 ctggtcacct gatgggatcc atggtacagg ctactgctaa acttggcaca 4300

 gtatcaagta tagtacctcc aaggaccagg gctgggaagt ctttagtgct 4350

 aacatcccct ttagagttca cacatcttgc ccttccatga atgacccctc 4400

 agtctggcct ccccagcctc aaggtccact caggcacaag agccacagta 4450

 ccctagatag tgtcacatga caccgttgtc atccaaggat aatacagacc 4500

 aactaggcta catctgtgat gagcagctag caaagccgct ggtcttctcc 4550

 taggactaag tccaggtgcc ttccacaatc tcatggtctt tcaggtccct 4600

 ggttactttt ctcaaaggcc atttccaaaa gaatacatgc cttcacatca 4650

 caacctgtac tgtgagtcca ttctagaggt cactgaaagg ccctgtaaag 4700

 agaggacatg gatacgggac ctggccctga ggttattact ggccgtaagg 4750

 cagagttaat ccatacagaa accagtgtgt ccatgtgctc tgcacaaaaa 4800

 cagacctgtt gtccatccag tccactgaca agagggtttc cccgagagcc 4850

 gaagtggact gaagctacag tttttagctg gtgcgggcca caggcagggt 4900

 cagattgaga agaagcaaag ctggggaagc agaagttggg agtcttgtgt 4950

 tgctccctct tcctgtgtgg tgctctgggt ttctgtggat cgtgaaggcg 5000

 atctcaagag tgtttccctc caaacctgat agctgcctat tcctgtctgg 5050

 ttggggctgt ggaggatgta gttgtattta ttgcattgta atatttttaa 5100

 catcctgtga cttcatgcta gaaattttct attgtttata gaaacttttt 5150

 gtagaaacat taactctaaa gcacatctgc atgtcagtaa aaatctcagt 5200

 ttcgtacaga aaaaaaaaaa aaaaaaaaaa a 5231

<210> 3816
<211> 1204
<212> PRT
<213> Homo sapien

<400> 3816
 Met Ala Met Asp Gln Val Asn Ala Leu Cys Glu Gln Leu Val Lys
   1               5                  10                  15

 Ala Val Thr Val Met Met Asp Pro Asn Ser Thr Gln Arg Tyr Arg
                  20                  25                  30

 Leu Glu Ala Leu Lys Phe Cys Glu Glu Phe Lys Glu Lys Cys Pro
                  35                  40                  45

 Ile Cys Val Pro Cys Gly Leu Arg Leu Ala Glu Lys Thr Gln Val
                  50                  55                  60

 Ala Ile Val Arg His Phe Gly Leu Gln Ile Leu Glu His Val Val
                  65                  70                  75

 Lys Phe Arg Trp Asn Gly Met Ser Arg Leu Glu Lys Val Tyr Leu
                  80                  85                  90

 Lys Asn Ser Val Met Glu Leu Ile Ala Asn Gly Thr Leu Asn Ile
                  95                 100                 105

 Leu Glu Glu Glu Asn His Ile Lys Asp Ala Leu Ser Arg Ile Val
                 110                 115                 120

 Val Glu Met Ile Lys Arg Glu Trp Pro Gln His Trp Pro Asp Met
                 125                 130                 135

 Leu Ile Glu Leu Asp Thr Leu Ser Lys Gln Gly Glu Thr Gln Thr
                 140                 145                 150

 Glu Leu Val Met Phe Ile Leu Leu Arg Leu Ala Glu Asp Val Val
                 155                 160                 165

 Thr Phe Gln Thr Leu Pro Pro Gln Arg Arg Arg Asp Ile Gln Gln
                 170                 175                 180

 Thr Leu Thr Gln Asn Met Glu Arg Ile Phe Ser Phe Leu Leu Asn
                 185                 190                 195

 Thr Leu Gln Glu Asn Val Asn Lys Tyr Gln Gln Val Lys Thr Asp
                 200                 205                 210

 Thr Ser Gln Glu Ser Lys Ala Gln Ala Asn Cys Arg Val Gly Val
                 215                 220                 225

 Ala Ala Leu Asn Thr Leu Ala Gly Tyr Ile Asp Trp Val Ser Met
                 230                 235                 240

 Ser His Ile Thr Ala Glu Asn Cys Lys Leu Leu Glu Ile Leu Cys
                 245                 250                 255

 Leu Leu Leu Asn Glu Gln Glu Leu Gln Leu Gly Ala Ala Glu Cys
                 260                 265                 270

 Leu Leu Ile Ala Val Ser Arg Lys Gly Lys Leu Glu Asp Arg Lys
                 275                 280                 285

 Pro Leu Met Val Leu Phe Gly Asp Val Ala Met His Tyr Ile Leu
                 290                 295                 300

 Ser Ala Ala Gln Thr Ala Asp Gly Gly Gly Leu Val Glu Lys His
                 305                 310                 315

 Tyr Val Phe Leu Lys Arg Leu Cys Gln Val Leu Cys Ala Leu Gly
                 320                 325                 330

 Asn Gln Leu Cys Ala Leu Leu Gly Ala Asp Ser Asp Val Glu Thr
                 335                 340                 345

 Pro Ser Asn Phe Gly Lys Tyr Leu Glu Ser Phe Leu Ala Phe Thr
                 350                 355                 360

 Thr His Pro Ser Gln Phe Leu Arg Ser Ser Thr Gln Met Thr Trp
                 365                 370                 375

 Gly Ala Leu Phe Arg His Glu Ile Leu Ser Arg Asp Pro Leu Leu
                 380                 385                 390

 Leu Ala Ile Ile Pro Lys Tyr Leu Arg Ala Ser Met Thr Asn Leu
                 395                 400                 405

 Val Lys Met Gly Phe Pro Ser Lys Thr Asp Ser Pro Ser Cys Glu
                 410                 415                 420

 Tyr Ser Arg Phe Asp Phe Asp Ser Asp Glu Asp Phe Asn Ala Phe
                 425                 430                 435

 Phe Asn Ser Ser Arg Ala Gln Gln Gly Glu Val Met Arg Leu Ala
                 440                 445                 450

 Cys Arg Leu Asp Pro Lys Thr Ser Phe Gln Met Ala Gly Glu Trp
                 455                 460                 465

 Leu Lys Tyr Gln Leu Ser Thr Phe Leu Asp Ala Gly Ser Val Asn
                 470                 475                 480

 Ser Cys Ser Ala Val Gly Thr Gly Glu Gly Ser Leu Cys Ser Val
                 485                 490                 495

 Phe Ser Pro Ser Phe Val Gln Trp Glu Ala Met Thr Leu Phe Leu
                 500                 505                 510

 Glu Ser Val Ile Thr Gln Met Phe Arg Thr Leu Asn Arg Glu Glu
                 515                 520                 525

 Ile Pro Val Asn Asp Gly Ile Glu Leu Leu Gln Met Val Leu Asn
                 530                 535                 540

 Phe Asp Thr Lys Asp Pro Leu Ile Leu Ser Cys Val Leu Thr Asn
                 545                 550                 555

 Val Ser Ala Leu Phe Pro Phe Val Thr Tyr Arg Pro Glu Phe Leu
                 560                 565                 570

 Pro Gln Val Phe Ser Lys Leu Phe Ser Ser Val Thr Phe Glu Thr
                 575                 580                 585

 Val Glu Glu Ser Lys Ala Pro Arg Thr Arg Ala Val Arg Asn Val
                 590                 595                 600

 Arg Arg His Ala Cys Ser Ser Ile Ile Lys Met Cys Arg Asp Tyr
                 605                 610                 615

 Pro Gln Leu Val Leu Pro Asn Phe Asp Met Leu Tyr Asn His Val
                 620                 625                 630

 Lys Gln Leu Leu Ser Asn Glu Leu Leu Leu Thr Gln Met Glu Lys
                 635                 640                 645

 Cys Ala Leu Met Glu Ala Leu Val Leu Ile Ser Asn Gln Phe Lys
                 650                 655                 660

 Asn Tyr Glu Arg Gln Lys Val Phe Leu Glu Glu Leu Met Ala Pro
                 665                 670                 675

 Val Ala Ser Ile Trp Leu Ser Gln Asp Met His Arg Val Leu Ser
                 680                 685                 690

 Asp Val Asp Ala Phe Ile Ala Tyr Val Gly Thr Asp Gln Lys Ser
                 695                 700                 705

 Cys Asp Pro Gly Leu Glu Asp Pro Cys Gly Leu Asn Arg Ala Arg
                 710                 715                 720

 Met Ser Phe Cys Val Tyr Ser Ile Leu Gly Val Val Lys Arg Thr
                 725                 730                 735

 Cys Trp Pro Thr Asp Leu Glu Glu Ala Lys Ala Gly Gly Phe Val
                 740                 745                 750

 Val Gly Tyr Thr Ser Ser Gly Asn Pro Ile Phe Arg Asn Pro Cys
                 755                 760                 765

 Thr Glu Gln Ile Leu Lys Leu Leu Asp Asn Leu Leu Ala Leu Ile
                 770                 775                 780

 Arg Thr His Asn Thr Leu Tyr Ala Pro Glu Met Leu Ala Lys Met
                 785                 790                 795

 Ala Glu Pro Phe Thr Lys Ala Leu Asp Met Leu Asp Ala Glu Lys
                 800                 805                 810

 Ser Ala Ile Leu Gly Leu Pro Gln Pro Leu Leu Glu Leu Asn Asp
                 815                 820                 825

 Ser Pro Val Phe Lys Thr Val Leu Glu Arg Met Gln Arg Phe Phe
                 830                 835                 840

 Ser Thr Leu Tyr Glu Asn Cys Phe His Ile Leu Gly Lys Ala Gly
                 845                 850                 855

 Pro Ser Met Gln Gln Asp Phe Tyr Thr Val Glu Asp Leu Ala Thr
                 860                 865                 870

 Gln Leu Leu Ser Ser Ala Phe Val Asn Leu Asn Asn Ile Pro Asp
                 875                 880                 885

 Tyr Arg Leu Arg Pro Met Leu Arg Val Phe Val Lys Pro Leu Val
                 890                 895                 900

 Leu Phe Cys Pro Pro Glu His Tyr Glu Ala Leu Val Ser Pro Ile
                 905                 910                 915

 Leu Gly Pro Leu Phe Thr Tyr Leu His Met Arg Leu Ser Gln Lys
                 920                 925                 930

 Trp Gln Val Ile Asn Gln Arg Ser Leu Leu Cys Gly Glu Asp Glu
                 935                 940                 945

 Ala Ala Asp Glu Asn Pro Glu Ser Gln Glu Met Leu Glu Glu Gln
                 950                 955                 960

 Leu Val Arg Met Leu Thr Arg Glu Val Met Asp Leu Ile Thr Val
                 965                 970                 975

 Cys Cys Val Ser Lys Lys Gly Ala Asp His Ser Ser Ala Pro Pro
                 980                 985                 990

 Ala Asp Gly Asp Asp Glu Glu Met Met Ala Thr Glu Val Thr Pro
                 995                1000                1005

 Ser Ala Met Ala Glu Leu Thr Asp Leu Gly Lys Cys Leu Met Lys
                1010                1015                1020

 His Glu Asp Val Cys Thr Ala Leu Leu Ile Thr Ala Phe Asn Ser
                1025                1030                1035

 Leu Ala Trp Lys Asp Thr Leu Ser Cys Gln Arg Thr Thr Ser Gln
                1040                1045                1050

 Leu Cys Trp Pro Leu Leu Lys Gln Val Leu Ser Gly Thr Leu Leu
                1055                1060                1065

 Ala Asp Ala Val Thr Trp Leu Phe Thr Ser Val Leu Lys Gly Leu
                1070                1075                1080

 Gln Met His Gly Gln His Asp Gly Cys Met Ala Ser Leu Val His
                1085                1090                1095

 Leu Ala Phe Gln Ile Tyr Glu Ala Leu Arg Pro Arg Tyr Leu Glu
                1100                1105                1110

 Ile Arg Ala Val Met Glu Gln Ile Pro Glu Ile Gln Lys Asp Ser
                1115                1120                1125

 Leu Asp Gln Phe Asp Cys Lys Leu Leu Asn Pro Ser Leu Gln Lys
                1130                1135                1140

 Val Ala Asp Lys Arg Arg Lys Asp Gln Phe Lys Arg Leu Ile Ala
                1145                1150                1155

 Gly Cys Ile Gly Lys Pro Leu Gly Glu Gln Phe Arg Lys Glu Val
                1160                1165                1170

 His Ile Lys Asn Leu Pro Ser Leu Phe Lys Lys Thr Lys Pro Met
                1175                1180                1185

 Leu Glu Thr Glu Val Leu Asp Asn Asp Gly Gly Gly Leu Ala Thr
                1190                1195                1200

 Ile Phe Glu Pro


<210> 3817
<211> 3301
<212> DNA
<213> Homo sapien

<400> 3817
 gagagccctc ctcaggggct gtctctgcct tcccttcttc ccatgtgtat 50

 ctggggcagc tgaggcaggg ctaggagaag agcccaggtt cctcctgcca 100

 cctccaagcg atgaagcagc cctgggccaa ctccagcatt ctcgtgtgaa 150

 ctgcagagga gccctgcgct tccagctact tgcagccaga cagcccacct 200

 gaggatattg accataagga ctcatatctc attacaagaa gcatcatggc 250

 cgagccagac tacatagaag atgacaatcc tgaactcatt aggcctcaga 300

 aactgatcaa tcctgtaaaa acctcccgga accatcaaga tcttcacaga 350

 gaacttctta tgaatcaaaa aaggggtctt gctcctcaga acaaaccaga 400

 attgcagaag gtgatggaaa aaagaaaacg agaccaagta ataaagcaga 450

 aggaagaaga agcacagaag aagaaatctg acttggaaat agagctatta 500

 aaacggcagc agaagttgga gcagcttgaa cttgagaagc agaaattgca 550

 agaagagcaa gaaaatgccc ccgagtttgt gaaggtgaaa ggcaatctca 600

 ggagaacagg ccaagaagtc gcccaagccc aggagtccta ggctgaggct 650

 gcaccaagac ctcgtgtgtc accccacaga gctgtctgtg ggtgccttct 700

 caatctcagg gcaaaagccc ctggagaata tttcagccag cagagaattt 750

 tgacttgcag taggatttgg tttgattttc ctacgatctg ggtggatgcc 800

 ttgcctgtga cagttgcagt tcctattcgc caaatgaagg gcagtgcccc 850

 gcacgtaagt tggaatgatg gacctgtgtt cagagactta acagaaccaa 900

 caagcaaaac aagtgagaac aggaaaaagg aagaggacac tggaatcaat 950

 tcttgagagt tgcactactt ggtttttctt ccattccaag tttcgtggga 1000

 cccagagcct tttttctttt aaaagctaaa aaacaagtgt ttaattcctc 1050

 tttttgttat ctgttagata attgagatca cctagaaatg cgtttaatct 1100

 gttcactcac tgtaaatttt gaggacccag aattgtcttg tttaatttat 1150

 actttcaccc ctgttgcagt taacaccaga gaaggaacgt gaatgtcgag 1200

 cacagccact acccttgttg gcacttaatt tagaaatagg gtgagaagtt 1250

 taaaagccca tcttgatttt attttcattc cttttggttc tctgtgtaat 1300

 aatagcaggc tacatagtga cattccagtt ccaagaaggt acatcctgtc 1350

 cattcattaa ttgctttgat tactaggagg gtttctgttc agttttgttt 1400

 ttaaatgtct tgctgatcta gttctttcag atggaataac cttccagtcc 1450

 cttagagagt ggaactagtc catataaccc agcttcagta gcaaaagtag 1500

 aagccgccac atcttttcat ttctccaaga ggagagtggg gaaggttccc 1550

 atgaccagct gggcagtcag gatttctcta ggcattctaa tgtgaaataa 1600

 gtgtagactg ctgtcaagga ggcttcatca gaagatgtat agcatttgaa 1650

 tgtctaatga taatgcatat cattagaatc caagctttga aaatttctga 1700

 ttaatgctca tgtatttctt tatctttgtt tttccttgtg aagaaagact 1750

 ttcaccactg tctgagtgat gatgctgttg ataaggatga tgtcgatgac 1800

 tactatattg catctctcag gaacagctga tgggaaggga ggggctgctg 1850

 agttcccttg ttctagctag cagcacgctc ctcagagagg gggccgagtt 1900

 acagacagca gccgcattct catgcaaaat tagttttaaa ctgctagtgt 1950

 gggcatcggt accttttgcc tgggtgatac cgaagaattg ttgaggattt 2000

 agtatgctcc gtagagacag ttcagccagt catttctgca ttggagagac 2050

 ttctcatact ttctttgaag actcatagaa agctggatct agagcttttg 2100

 aatccttaat tagcacagta gaaattagct ttctatggga atgctttagt 2150

 gttagcagtt gacaattagg cccatattca atctgaatgg gaacaaaagt 2200

 aaatgcaatg ataatatact gctagttaga gaaacatgtt agttgattat 2250

 acctgaaatg gattatttat ctcatcagca agtattattt gaataaaatg 2300

 agaaatgctt aagaaaaatt gttgctctac agtaatttgg tttcgaagaa 2350

 tggaatggta actatttttt cccatcgttc ttttgagaga aggaagtgtg 2400

 atgactgatg atcttgaaaa gcccatttct gattgcacgt tgactggaat 2450

 tctttctttg tgtctgtgga ctagcgatgc tgtttgtaaa atgaagattc 2500

 gggactggct catatctttt tatctaacta gatgtcagat cttgaaatct 2550

 gtattctcga agcaattctg ccacttgatc gtattcacag gggccctggt 2600

 aggctccttt agaaggacca tttctgttcc tagagcttaa ctagaattca 2650

 ttcttcactg aaaaaaaaaa aagttactta agaaagcatt tctttcctaa 2700

 tctcactcaa atctgcagaa ttatttgtaa ttagtaatac aaaatctggc 2750

 caaaaggaga cttgtaaata gcgtaaagtg gtgtcttatg ctaaacggtg 2800

 gaatgtatag gcagagaagc tctttgaagt tgtcagatga gctgggctca 2850

 caagcctgat tcaaacaggc tgtcggtctc ctctcacccc ttaatactgt 2900

 gcagcccaaa ctcctaggac tcttgaacat ctgagcagtt ttgtgctttg 2950

 agccactttt tgacaaaaat ggctccattt ttccacagcg tggttttctt 3000

 aaaatagttt aatgttttat agtctcatag tagtagtgtt gctttctaag 3050

 ctataacagt cgactttatt cttctactct gaaaaatctt gacttgtttg 3100

 agtgtatata atatatataa agggagcctt aatggattgg ttttcataat 3150

 ttaatatttt ttgtatttgc tcttgtataa ttgtttttaa cggaaagtat 3200

 taaagaattg agggtggaat tcttagaacc aaagttattc ttaataaaaa 3250

 tcaccacatg cttggaccat gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3300

 a 3301

<210> 3818
<211> 131
<212> PRT
<213> Homo sapien

<400> 3818
 Met Ala Glu Pro Asp Tyr Ile Glu Asp Asp Asn Pro Glu Leu Ile
   1               5                  10                  15

 Arg Pro Gln Lys Leu Ile Asn Pro Val Lys Thr Ser Arg Asn His
                  20                  25                  30

 Gln Asp Leu His Arg Glu Leu Leu Met Asn Gln Lys Arg Gly Leu
                  35                  40                  45

 Ala Pro Gln Asn Lys Pro Glu Leu Gln Lys Val Met Glu Lys Arg
                  50                  55                  60

 Lys Arg Asp Gln Val Ile Lys Gln Lys Glu Glu Glu Ala Gln Lys
                  65                  70                  75

 Lys Lys Ser Asp Leu Glu Ile Glu Leu Leu Lys Arg Gln Gln Lys
                  80                  85                  90

 Leu Glu Gln Leu Glu Leu Glu Lys Gln Lys Leu Gln Glu Glu Gln
                  95                 100                 105

 Glu Asn Ala Pro Glu Phe Val Lys Val Lys Gly Asn Leu Arg Arg
                 110                 115                 120

 Thr Gly Gln Glu Val Ala Gln Ala Gln Glu Ser
                 125                 130

<210> 3819
<211> 2091
<212> DNA
<213> Homo sapien

<400> 3819
 ggcacgaggg ccaggaacgc cagccgttca cgcgttcggt cctccttggc 50

 tgactcaccg ccctcgccgc cgcaccatgg acgcccccag gcaggtggtc 100

 aactttgggc ctggtcccgc caagctgccg cactcagtgt tgttagagat 150

 acaaaaggaa ttattagact acaaaggagt tggcattagt gttcttgaaa 200

 tgagtcacag gtcatcagat tttgccaaga ttattaacaa tacagagaat 250

 cttgtgcggg aattgctagc tgttccagac aactataagg tgatttttct 300

 gcaaggaggt gggtgcggcc agttcagtgc tgtcccctta aacctcattg 350

 gcttgaaagc aggaaggtgt gcggactatg tggtgacagg agcttggtca 400

 gctaaggccg cagaagaagc caagaagttt gggactataa atatcgttca 450

 ccctaaactt gggagttata caaaaattcc agatccaagc acctggaacc 500

 tcaacccaga tgcctcctac gtgtattatt gcgcaaatga gacggtgcat 550

 ggtgtggagt ttgactttat acccgatgtc aagggagcag tactggtttg 600

 tgacatgtcc tcaaacttcc tgtccaagcc agtggatgtt tccaagtttg 650

 gtgtgatttt tgctggtgcc cagaagaatg ttggctctgc tggggtcacc 700

 gtggtgattg tccgtgatga cctgctgggg tttgccctcc gagagtgccc 750

 ctcggtcctg gaatacaagg tgcaggctgg aaacagctcc ttgtacaaca 800

 cgcctccatg tttcagcatc tacgtcatgg gcttggttct ggagtggatt 850

 aaaaacaatg gaggtgccgc ggccatggag aagcttagct ccatcaaatc 900

 tcaaacaatt tatgagatta ttgataattc tcaaggattc tacgtgtctg 950

 tgggaggcat ccgggcctct ctgtataatg ctgtcacaat tgaagacgtt 1000

 cagaagctgg ccgccttcat gaaaaaattt ttggagatgc atcagctatg 1050

 aacacatcct aaccaggata tactctgttc ttgaacaaca tacaaagttt 1100

 aaagtaactt ggggatggct acaaaaagtt aacacagtat ttttctcaaa 1150

 tgaacatgtt tattgcagat tcttcttttt tgaaagaaca acagcaaaac 1200

 atccacaact ctgtaaagct ggtgggacct aatgtcacct taattctgac 1250

 ttgaactgga agcattttaa gaaatcttgt tgcttttcta acaaattccc 1300

 gcgtattttg cctttgctgc tactttttct agttagattt caaacttgcc 1350

 tgtggactta ataatgcaag ttgcgattaa ttatttctgg agtcatggga 1400

 acacacagca cagagggtag gggggccctc taggtgctga atctacacat 1450

 ctgtggggtc tcctgggttc agcggctgtt gattcaaggt caacattgac 1500

 cattggagga gtggtttaag agtgccaggc gaagggcaaa ctgtagatcg 1550

 atctttatgc tgttattaca ggagaagtga catactttat atatgtttat 1600

 attagcaagg tctgttttta ataccatata ctttatattt ctatacattt 1650

 atatttctaa taatacagtt atcactgata tatgtagaca cttttagaat 1700

 ttattaaatc cttgaccttg tgcattatag cattccatta gcaagagttg 1750

 taccccctcc ccagtcttcg ccttcctctt tttaagctgt tttatgaaaa 1800

 agacctagaa gttcttgatt catttttacc attctttcca taggtagaag 1850

 agaaagttga ttggttggtt gtttttcaat tatgccatta aactaaacat 1900

 ttctgttaaa ttaccctatc ctttgttctc tactgttttc tttgtaatgt 1950

 atgactacga gagtgatact ttgctgaaaa gtctttcccc tattgtttat 2000

 ctattgtcag tattttatgt tgaatatgta aagaacatta aagtcctaaa 2050

 acatctaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 2091

<210> 3820
<211> 324
<212> PRT
<213> Homo sapien

<400> 3820
 Met Asp Ala Pro Arg Gln Val Val Asn Phe Gly Pro Gly Pro Ala
   1               5                  10                  15

 Lys Leu Pro His Ser Val Leu Leu Glu Ile Gln Lys Glu Leu Leu
                  20                  25                  30

 Asp Tyr Lys Gly Val Gly Ile Ser Val Leu Glu Met Ser His Arg
                  35                  40                  45

 Ser Ser Asp Phe Ala Lys Ile Ile Asn Asn Thr Glu Asn Leu Val
                  50                  55                  60

 Arg Glu Leu Leu Ala Val Pro Asp Asn Tyr Lys Val Ile Phe Leu
                  65                  70                  75

 Gln Gly Gly Gly Cys Gly Gln Phe Ser Ala Val Pro Leu Asn Leu
                  80                  85                  90

 Ile Gly Leu Lys Ala Gly Arg Cys Ala Asp Tyr Val Val Thr Gly
                  95                 100                 105

 Ala Trp Ser Ala Lys Ala Ala Glu Glu Ala Lys Lys Phe Gly Thr
                 110                 115                 120

 Ile Asn Ile Val His Pro Lys Leu Gly Ser Tyr Thr Lys Ile Pro
                 125                 130                 135

 Asp Pro Ser Thr Trp Asn Leu Asn Pro Asp Ala Ser Tyr Val Tyr
                 140                 145                 150

 Tyr Cys Ala Asn Glu Thr Val His Gly Val Glu Phe Asp Phe Ile
                 155                 160                 165

 Pro Asp Val Lys Gly Ala Val Leu Val Cys Asp Met Ser Ser Asn
                 170                 175                 180

 Phe Leu Ser Lys Pro Val Asp Val Ser Lys Phe Gly Val Ile Phe
                 185                 190                 195

 Ala Gly Ala Gln Lys Asn Val Gly Ser Ala Gly Val Thr Val Val
                 200                 205                 210

 Ile Val Arg Asp Asp Leu Leu Gly Phe Ala Leu Arg Glu Cys Pro
                 215                 220                 225

 Ser Val Leu Glu Tyr Lys Val Gln Ala Gly Asn Ser Ser Leu Tyr
                 230                 235                 240

 Asn Thr Pro Pro Cys Phe Ser Ile Tyr Val Met Gly Leu Val Leu
                 245                 250                 255

 Glu Trp Ile Lys Asn Asn Gly Gly Ala Ala Ala Met Glu Lys Leu
                 260                 265                 270

 Ser Ser Ile Lys Ser Gln Thr Ile Tyr Glu Ile Ile Asp Asn Ser
                 275                 280                 285

 Gln Gly Phe Tyr Val Ser Val Gly Gly Ile Arg Ala Ser Leu Tyr
                 290                 295                 300

 Asn Ala Val Thr Ile Glu Asp Val Gln Lys Leu Ala Ala Phe Met
                 305                 310                 315

 Lys Lys Phe Leu Glu Met His Gln Leu
                 320

<210> 3821
<211> 1591
<212> DNA
<213> Homo sapien

<400> 3821
 agcctggggc ggccggccag gaaccacccg ttaaggtgtc ttctctttag 50

 ggatggtgag gttggaaaaa ggctcctgta accctcctcc aggatgaacc 100

 acctgccaga agacatggag aacgctctca ccgggagcca gagctcccat 150

 gcttctctgc gcaatatcca ttccatcaac cccacacaac tcatggccag 200

 gattgagtcc tatgaaggaa gggaaaagaa aggcatatct gatgtcagga 250

 ggactttctg tttgtttgtc acctttgacc tcttattcgt aacattactg 300

 tggataatag agttaaatgt gaatggaggc attgagaaca cattagagaa 350

 ggaggtgatg cagtatgact actattcttc atattttgat atatttcttc 400

 tggcagtttt tcgatttaaa gtgttaatac ttgcatatgc tgtgtgcaga 450

 ctgcgccatt ggtgggcaat agcgttgaca acggcagtga ccagtgcctt 500

 tttactagca aaagtgatcc tttcgaagct tttctctcaa ggggcttttg 550

 gctatgtgct gcccatcatt tcattcatcc ttgcctggat tgagacgtgg 600

 ttcctggatt tcaaagtgtt acctcaagaa gcagaagaag aaaacagact 650

 cctgatagtt caggatgctt cagagagggc agcacttata cctggtggtc 700

 tttctgatgg tcagttttat tcccctcctg aatccgaagc aggatctgaa 750

 gaagctgaag aaaaacagga cagtgagaaa ccacttttag aactatgagt 800

 actacttttg ttaaatgtga aaaaccctca cagaaagtca tcgaggcaaa 850

 aagaggcagg cagtggagtc tccctgtcga cagtaaagtt gaaatggtga 900

 cgtccactgc tggctttatt gaacagctaa taaagattta tttattgtaa 950

 tacctcacag acgttgcacc atatccatgc acatttagtt gcctgcctgt 1000

 ggctggtaag gtaatgtcat gattcatcct ctcttcagtg agactgagcc 1050

 tgatgtgtta acaaataggt gaagaaagtc ttgtgctgta ttcctaatca 1100

 aaagacttaa tatattgaag taacactttt ttagtaagca agataccttt 1150

 ttatttcaat tcacagaatg gaattttttt gtttcatgtc tcagatttat 1200

 tttgtatttc ttttttaaca ctctacattt cccttgtttt ttaactcatg 1250

 cacatgtgct ctttgtacag ttttaaaaag tgtaataaaa tctgacatgt 1300

 caatgtggct agttttattt ttcttgtttt gcattatgtg tatggcctga 1350

 agtgttggac ttgcaaaagg ggaagaaagg aattgcgaat acatgtaaaa 1400

 tgtcaccaga catttgtatt atttttatca tgaaatcatg tttttctctg 1450

 attgttctga aatgttctaa atactcttat tttgaatgca caaaatgact 1500

 taaaccattc atatcatgtt tcctttgcgt tcagccaatt tcaattaaaa 1550

 tgaactaaat taaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1591

<210> 3822
<211> 234
<212> PRT
<213> Homo sapien

<400> 3822
 Met Asn His Leu Pro Glu Asp Met Glu Asn Ala Leu Thr Gly Ser
   1               5                  10                  15

 Gln Ser Ser His Ala Ser Leu Arg Asn Ile His Ser Ile Asn Pro
                  20                  25                  30

 Thr Gln Leu Met Ala Arg Ile Glu Ser Tyr Glu Gly Arg Glu Lys
                  35                  40                  45

 Lys Gly Ile Ser Asp Val Arg Arg Thr Phe Cys Leu Phe Val Thr
                  50                  55                  60

 Phe Asp Leu Leu Phe Val Thr Leu Leu Trp Ile Ile Glu Leu Asn
                  65                  70                  75

 Val Asn Gly Gly Ile Glu Asn Thr Leu Glu Lys Glu Val Met Gln
                  80                  85                  90

 Tyr Asp Tyr Tyr Ser Ser Tyr Phe Asp Ile Phe Leu Leu Ala Val
                  95                 100                 105

 Phe Arg Phe Lys Val Leu Ile Leu Ala Tyr Ala Val Cys Arg Leu
                 110                 115                 120

 Arg His Trp Trp Ala Ile Ala Leu Thr Thr Ala Val Thr Ser Ala
                 125                 130                 135

 Phe Leu Leu Ala Lys Val Ile Leu Ser Lys Leu Phe Ser Gln Gly
                 140                 145                 150

 Ala Phe Gly Tyr Val Leu Pro Ile Ile Ser Phe Ile Leu Ala Trp
                 155                 160                 165

 Ile Glu Thr Trp Phe Leu Asp Phe Lys Val Leu Pro Gln Glu Ala
                 170                 175                 180

 Glu Glu Glu Asn Arg Leu Leu Ile Val Gln Asp Ala Ser Glu Arg
                 185                 190                 195

 Ala Ala Leu Ile Pro Gly Gly Leu Ser Asp Gly Gln Phe Tyr Ser
                 200                 205                 210

 Pro Pro Glu Ser Glu Ala Gly Ser Glu Glu Ala Glu Glu Lys Gln
                 215                 220                 225

 Asp Ser Glu Lys Pro Leu Leu Glu Leu
                 230

<210> 3823
<211> 5539
<212> DNA
<213> Homo sapien

<400> 3823
 ggagggaggc cgggcaggcg gctgagcggc gcggctctca acgtgacggg 50

 gaagtggttc gggcggccgc ggcttactac cccagggcga acggacggac 100

 gacggaggcg ggagccggta gccgagccgg gcgacctaga gaacgagcgg 150

 gtcaggctca gcgtcggcca ctctgtcggt ccgctgaatg aagtgcccgc 200

 ccctctaagc ccggagcccg gcgctttccc cgcaagatgg acggtttcgc 250

 cggcagtctc gatgatagta tttctgctgc aagtacttct gatgttcaag 300

 atcgcctgtc agctcttgag tcacgagttc agcaacaaga agatgaaatc 350

 actgtgctaa aggcggcttt ggctgatgtt ttgaggcgtc ttgcaatctc 400

 tgaagatcat gtggcctcag tgaaaaaatc agtctcaagt aaaggccaac 450

 caagccctcg agcagttatt cccatgtcct gtataaccaa tggaagtggt 500

 gcaaacagaa aaccaagtca taccagtgct gtctcaattg caggaaaaga 550

 aactctttca tctgctgcta aaagtggtac agaaaaaaag aaagaaaaac 600

 cacaaggaca gagagaaaaa aaagaggaat ctcattctaa tgatcaaagt 650

 ccacaaattc gagcatcacc ttctccccag ccctcttcac aacctctcca 700

 aatacacaga caaactccag aaagcaagaa tgctactccc accaaaagca 750

 taaaacgacc atcaccagct gaaaagtcac ataattcttg ggaaaattca 800

 gatgatagcc gtaataaatt gtcgaaaata ccttcaacac ccaaattaat 850

 accaaaagtt accaaaactg cagacaagca taaagatgtc atcatcaacc 900

 aagaaggaga atatattaaa atgtttatgc gcggtcggcc aattaccatg 950

 ttcattcctt ccgatgttga caactatgat gacatcagaa cggaactgcc 1000

 tcctgagaag ctcaaactgg agtgggcata tggttatcga ggaaaggact 1050

 gtagagctaa tgtttacctt cttccgaccg gggaaatagt ttatttcatt 1100

 gcatcagtag tagtactatt taattatgag gagagaactc agcgacacta 1150

 cctgggccat acagactgtg tgaaatgcct tgctatacat cctgacaaaa 1200

 ttaggattgc aactggacag atagctggcg tggataaaga tggaaggcct 1250

 ctacaacccc acgtcagagt gtgggattct gttactctat ccacactgca 1300

 gattattgga cttggcactt ttgagcgtgg agtaggatgc ctggattttt 1350

 caaaagcaga ttcaggtgtt catttatgtg ttattgatga ctccaatgag 1400

 catatgctta ctgtatggga ctggcagaag aaagcaaaag gagcagaaat 1450

 aaagacaaca aatgaagttg ttttggctgt ggagtttcac ccaacagatg 1500

 caaataccat aattacatgc ggtaaatctc atattttctt ctggacctgg 1550

 agcggcaatt cactaacaag aaaacaggga atttttggga aatatgaaaa 1600

 gccaaaattt gtgcagtgtt tagcattctt ggggaatgga gatgttctta 1650

 ctggagactc aggtggagtc atgcttatat ggagcaaaac tactgtagag 1700

 cccacacctg ggaaaggacc taaaggtgta tatcaaatca gcaaacaaat 1750

 caaagctcat gatggcagtg tgttcacact ttgtcagatg agaaatggga 1800

 tgttattaac tggaggaggg aaagacagaa aaataattct gtgggatcat 1850

 gatctgaatc ctgaaagaga aatagaggtt cctgatcagt atggcacaat 1900

 cagagctgta gcagaaggaa aggcagatca atttttagta ggcacatcac 1950

 gaaactttat tttacgagga acatttaatg atggcttcca aatagaagta 2000

 cagggtcata cagatgagct ttggggtctt gccacacatc ccttcaaaga 2050

 tttgctcttg acatgtgctc aggacaggca ggtgtgcctg tggaactcaa 2100

 tggaacacag gctggaatgg accaggctgg tagatgaacc aggacactgt 2150

 gcagattttc atccaagtgg cacagtggtg gccataggaa cgcactcagg 2200

 caggtggttt gttctggatg cagaaaccag agatctagtt tctatccaca 2250

 cagacgggaa tgaacagctc tctgtgatgc gctactcaat agatggtacc 2300

 ttcctggctg taggatctca tgacaacttt atttacctct atgtagtctc 2350

 tgaaaatgga agaaaatata gcagatatgg aaggtgcact ggacattcca 2400

 gctacatcac acaccttgac tggtccccag acaacaagta tataatgtct 2450

 aactcgggag actatgaaat attgtactgg gacattccaa atggctgcaa 2500

 actaatcagg aatcgatcgg attgtaagga cattgattgg acgacatata 2550

 cctgtgtgct aggatttcaa gtatttggtg tctggccaga aggatctgat 2600

 gggacagata tcaatgcact ggtgcgatcc cacaatagaa aggtgatagc 2650

 tgttgccgat gacttttgta aagtccatct gtttcagtat ccctgctcca 2700

 aagcaaaggc tcccagtcac aagtacagtg cccacagcag ccatgtcacc 2750

 aatgtcagtt ttactcacaa tgacagtcac ctgatatcaa ctggtggaaa 2800

 agacatgagc atcattcagt ggaaacttgt ggaaaagtta tctttgcctc 2850

 agaatgagac tgtagcggat actactctaa ccaaagcccc cgtctcttcc 2900

 actgaaagtg tcatccaatc taatactccc acaccgcctc cttctcagcc 2950

 cttaaatgag acagctgaag aggaaagtag aataagcagt tctcccacac 3000

 ttctggagaa cagcctggaa caaactgtgg agccaagtga agaccacagc 3050

 gaggaggaga gtgaagaggg cagcggagac cttggtgagc ctctttatga 3100

 agagccatgc aacgagataa gcaaggagca ggccaaagcc acccttctgg 3150

 aggaccagca agacccttcg ccctcgtcct aacaccctgg cttcagtgca 3200

 actcttttcc ttcagctgca tgtgattttg tgataaagtt caggtaacag 3250

 gatgggcagt gatggagaat cactgttgat tgagattttg gtttccatgt 3300

 gatttgtttt cttcaatagt cttattttca gtctctcaaa tacagccaac 3350

 ttaaagtttt agtttggtgt ttattgaaaa ttaaccaaac ttaatactag 3400

 gagaagactg aatcattaat gatgtctcac aaattactgt gtacctaagt 3450

 ggtgtgatgt aaatactgga aacaaaaaca gcagttgcat tgattttgaa 3500

 aacaaacccc cttgttatct gaacatgttt tcttcaggaa caaccagagg 3550

 tatcacaaac actgttactc atctactggc tcagactgta ctactttttt 3600

 tttttttttt cctgaaaaag aaaccagaaa aaaatgtact cttactgaga 3650

 taccctctca ccccaaatgt gtaatggaaa atttttaatt aagaaaaact 3700

 tcagttttgc caagtgcaat ggtgttgcct tctttaaaaa atgccgtttt 3750

 cttacactac cagtggatgt ccagacatgc tcttagtcta ctagagaggt 3800

 gctgcctttt ctaagtcata atgaggaaca gtcccttaat ttcttgtgtg 3850

 caactctgtt ttatcctaga actaagagag cattggtttg ttaaagagct 3900

 ttcaatgtat attaaaacct tcaatactca gaaatgatgg attcctccaa 3950

 ggagtccttt actagcctaa acattctcaa atgtttgaga ttcaagtgaa 4000

 tggaaggaaa accacatgcc tttaaaacta aactgtaata attacctggc 4050

 taatttcagc taagccttca tcataatttg ttccctcagt aataggagaa 4100

 atataaatac agtaagttta gattattgaa ttggtgcttg aaatttattg 4150

 gttttgttgt aattttatac agattatatg agggataaga tactcatcaa 4200

 attgcaaatt ctttttttta cagaagtgtg ggtaacagtc acagcagttt 4250

 tttttaccaa cagcatactt aacagacttg ctgtgtagca gtttttttct 4300

 ggtggagttg ctgtaagtct tgtaagtcta atgtggctat cctactcttt 4350

 tgggcaatgc atgtattatg cattggaaag gtattttttt taagttctgt 4400

 tggctagcta tggttttcag tacatttcct actttaagag taattactga 4450

 caaatatgta tttcctatat gtttatactt tgattataaa aaagtatttt 4500

 gttttgattt tttaacttgc tgcattgttt tgatactttc tatttttttg 4550

 gtcaaatcat gtttagaaac tttggatgag ttaagaagtc ttaagtatgc 4600

 aggcgtttac gtgattgtgc cattccaaag tgcatcagaa ctgtcattcc 4650

 cttctaatat cttctcagga gtaatacaaa tcaggtattt catcatcatt 4700

 tggtaatatg aaaactccag tgaactccca aggacattta caacatttat 4750

 attcacacgc tgtatggaag ggtgtgggtg tgtgtgaagg ggcgagtgga 4800

 gacactgtgt gtatctctag ataagaagat atgcaccacg ttgaaaatac 4850

 tcagtgtaga tctctatgtg tataggtatc tgtatatctt tccttttgtt 4900

 tacaactgtt aaaaaacctc aaaatagttc tcttcaaaag aagagagatt 4950

 ccaagcaacc catctttctt cagtatgtat gttctgtaca tacttatcgg 5000

 agcgcgccag taagtatcag gcatatatat ctgtctgtta gcaatgatta 5050

 ttacatcatc agatcagcat gtgctatact ccctgcaaga aatatactga 5100

 catgaacagg cagttcttgg agaagaaaga gcatttcttt aagtacctgg 5150

 ggaatacagc tctcagtgat cagcagggag tttatttgag gacatcagtc 5200

 acctttgggg ttgccatgta caatgagatt tataatcatg atactcttcg 5250

 gtggtagttt caaaagacac tactaatacg caggaagcgt tccagctatt 5300

 taatgctggc aactactgtt taatggtcag ttaaatctgt gataatggtt 5350

 ggaagtgggt ggggttatga aattgtagat gtttttagaa aaacttgtga 5400

 atgaaaatga atccaagtgt ttcatgtgaa gatgttgagc cattgctatc 5450

 atgcattcct gtctcatggc agaaaatttt gaagattaaa aaataaaata 5500

 atcaaaatgt ttcctctttc taaaaaaaaa aaaaaaaaa 5539

<210> 3824
<211> 981
<212> PRT
<213> Homo sapien

<400> 3824
 Met Asp Gly Phe Ala Gly Ser Leu Asp Asp Ser Ile Ser Ala Ala
   1               5                  10                  15

 Ser Thr Ser Asp Val Gln Asp Arg Leu Ser Ala Leu Glu Ser Arg
                  20                  25                  30

 Val Gln Gln Gln Glu Asp Glu Ile Thr Val Leu Lys Ala Ala Leu
                  35                  40                  45

 Ala Asp Val Leu Arg Arg Leu Ala Ile Ser Glu Asp His Val Ala
                  50                  55                  60

 Ser Val Lys Lys Ser Val Ser Ser Lys Gly Gln Pro Ser Pro Arg
                  65                  70                  75

 Ala Val Ile Pro Met Ser Cys Ile Thr Asn Gly Ser Gly Ala Asn
                  80                  85                  90

 Arg Lys Pro Ser His Thr Ser Ala Val Ser Ile Ala Gly Lys Glu
                  95                 100                 105

 Thr Leu Ser Ser Ala Ala Lys Ser Gly Thr Glu Lys Lys Lys Glu
                 110                 115                 120

 Lys Pro Gln Gly Gln Arg Glu Lys Lys Glu Glu Ser His Ser Asn
                 125                 130                 135

 Asp Gln Ser Pro Gln Ile Arg Ala Ser Pro Ser Pro Gln Pro Ser
                 140                 145                 150

 Ser Gln Pro Leu Gln Ile His Arg Gln Thr Pro Glu Ser Lys Asn
                 155                 160                 165

 Ala Thr Pro Thr Lys Ser Ile Lys Arg Pro Ser Pro Ala Glu Lys
                 170                 175                 180

 Ser His Asn Ser Trp Glu Asn Ser Asp Asp Ser Arg Asn Lys Leu
                 185                 190                 195

 Ser Lys Ile Pro Ser Thr Pro Lys Leu Ile Pro Lys Val Thr Lys
                 200                 205                 210

 Thr Ala Asp Lys His Lys Asp Val Ile Ile Asn Gln Glu Gly Glu
                 215                 220                 225

 Tyr Ile Lys Met Phe Met Arg Gly Arg Pro Ile Thr Met Phe Ile
                 230                 235                 240

 Pro Ser Asp Val Asp Asn Tyr Asp Asp Ile Arg Thr Glu Leu Pro
                 245                 250                 255

 Pro Glu Lys Leu Lys Leu Glu Trp Ala Tyr Gly Tyr Arg Gly Lys
                 260                 265                 270

 Asp Cys Arg Ala Asn Val Tyr Leu Leu Pro Thr Gly Glu Ile Val
                 275                 280                 285

 Tyr Phe Ile Ala Ser Val Val Val Leu Phe Asn Tyr Glu Glu Arg
                 290                 295                 300

 Thr Gln Arg His Tyr Leu Gly His Thr Asp Cys Val Lys Cys Leu
                 305                 310                 315

 Ala Ile His Pro Asp Lys Ile Arg Ile Ala Thr Gly Gln Ile Ala
                 320                 325                 330

 Gly Val Asp Lys Asp Gly Arg Pro Leu Gln Pro His Val Arg Val
                 335                 340                 345

 Trp Asp Ser Val Thr Leu Ser Thr Leu Gln Ile Ile Gly Leu Gly
                 350                 355                 360

 Thr Phe Glu Arg Gly Val Gly Cys Leu Asp Phe Ser Lys Ala Asp
                 365                 370                 375

 Ser Gly Val His Leu Cys Val Ile Asp Asp Ser Asn Glu His Met
                 380                 385                 390

 Leu Thr Val Trp Asp Trp Gln Lys Lys Ala Lys Gly Ala Glu Ile
                 395                 400                 405

 Lys Thr Thr Asn Glu Val Val Leu Ala Val Glu Phe His Pro Thr
                 410                 415                 420

 Asp Ala Asn Thr Ile Ile Thr Cys Gly Lys Ser His Ile Phe Phe
                 425                 430                 435

 Trp Thr Trp Ser Gly Asn Ser Leu Thr Arg Lys Gln Gly Ile Phe
                 440                 445                 450

 Gly Lys Tyr Glu Lys Pro Lys Phe Val Gln Cys Leu Ala Phe Leu
                 455                 460                 465

 Gly Asn Gly Asp Val Leu Thr Gly Asp Ser Gly Gly Val Met Leu
                 470                 475                 480

 Ile Trp Ser Lys Thr Thr Val Glu Pro Thr Pro Gly Lys Gly Pro
                 485                 490                 495

 Lys Gly Val Tyr Gln Ile Ser Lys Gln Ile Lys Ala His Asp Gly
                 500                 505                 510

 Ser Val Phe Thr Leu Cys Gln Met Arg Asn Gly Met Leu Leu Thr
                 515                 520                 525

 Gly Gly Gly Lys Asp Arg Lys Ile Ile Leu Trp Asp His Asp Leu
                 530                 535                 540

 Asn Pro Glu Arg Glu Ile Glu Val Pro Asp Gln Tyr Gly Thr Ile
                 545                 550                 555

 Arg Ala Val Ala Glu Gly Lys Ala Asp Gln Phe Leu Val Gly Thr
                 560                 565                 570

 Ser Arg Asn Phe Ile Leu Arg Gly Thr Phe Asn Asp Gly Phe Gln
                 575                 580                 585

 Ile Glu Val Gln Gly His Thr Asp Glu Leu Trp Gly Leu Ala Thr
                 590                 595                 600

 His Pro Phe Lys Asp Leu Leu Leu Thr Cys Ala Gln Asp Arg Gln
                 605                 610                 615

 Val Cys Leu Trp Asn Ser Met Glu His Arg Leu Glu Trp Thr Arg
                 620                 625                 630

 Leu Val Asp Glu Pro Gly His Cys Ala Asp Phe His Pro Ser Gly
                 635                 640                 645

 Thr Val Val Ala Ile Gly Thr His Ser Gly Arg Trp Phe Val Leu
                 650                 655                 660

 Asp Ala Glu Thr Arg Asp Leu Val Ser Ile His Thr Asp Gly Asn
                 665                 670                 675

 Glu Gln Leu Ser Val Met Arg Tyr Ser Ile Asp Gly Thr Phe Leu
                 680                 685                 690

 Ala Val Gly Ser His Asp Asn Phe Ile Tyr Leu Tyr Val Val Ser
                 695                 700                 705

 Glu Asn Gly Arg Lys Tyr Ser Arg Tyr Gly Arg Cys Thr Gly His
                 710                 715                 720

 Ser Ser Tyr Ile Thr His Leu Asp Trp Ser Pro Asp Asn Lys Tyr
                 725                 730                 735

 Ile Met Ser Asn Ser Gly Asp Tyr Glu Ile Leu Tyr Trp Asp Ile
                 740                 745                 750

 Pro Asn Gly Cys Lys Leu Ile Arg Asn Arg Ser Asp Cys Lys Asp
                 755                 760                 765

 Ile Asp Trp Thr Thr Tyr Thr Cys Val Leu Gly Phe Gln Val Phe
                 770                 775                 780

 Gly Val Trp Pro Glu Gly Ser Asp Gly Thr Asp Ile Asn Ala Leu
                 785                 790                 795

 Val Arg Ser His Asn Arg Lys Val Ile Ala Val Ala Asp Asp Phe
                 800                 805                 810

 Cys Lys Val His Leu Phe Gln Tyr Pro Cys Ser Lys Ala Lys Ala
                 815                 820                 825

 Pro Ser His Lys Tyr Ser Ala His Ser Ser His Val Thr Asn Val
                 830                 835                 840

 Ser Phe Thr His Asn Asp Ser His Leu Ile Ser Thr Gly Gly Lys
                 845                 850                 855

 Asp Met Ser Ile Ile Gln Trp Lys Leu Val Glu Lys Leu Ser Leu
                 860                 865                 870

 Pro Gln Asn Glu Thr Val Ala Asp Thr Thr Leu Thr Lys Ala Pro
                 875                 880                 885

 Val Ser Ser Thr Glu Ser Val Ile Gln Ser Asn Thr Pro Thr Pro
                 890                 895                 900

 Pro Pro Ser Gln Pro Leu Asn Glu Thr Ala Glu Glu Glu Ser Arg
                 905                 910                 915

 Ile Ser Ser Ser Pro Thr Leu Leu Glu Asn Ser Leu Glu Gln Thr
                 920                 925                 930

 Val Glu Pro Ser Glu Asp His Ser Glu Glu Glu Ser Glu Glu Gly
                 935                 940                 945

 Ser Gly Asp Leu Gly Glu Pro Leu Tyr Glu Glu Pro Cys Asn Glu
                 950                 955                 960

 Ile Ser Lys Glu Gln Ala Lys Ala Thr Leu Leu Glu Asp Gln Gln
                 965                 970                 975

 Asp Pro Ser Pro Ser Ser
                 980

<210> 3825
<211> 5539
<212> DNA
<213> Homo sapien

<400> 3825
 ggagggaggc cgggcaggcg gctgagcggc gcggctctca acgtgacggg 50

 gaagtggttc gggcggccgc ggcttactac cccagggcga acggacggac 100

 gacggaggcg ggagccggta gccgagccgg gcgacctaga gaacgagcgg 150

 gtcaggctca gcgtcggcca ctctgtcggt ccgctgaatg aagtgcccgc 200

 ccctctaagc ccggagcccg gcgctttccc cgcaagatgg acggtttcgc 250

 cggcagtctc gatgatagta tttctgctgc aagtacttct gatgttcaag 300

 atcgcctgtc agctcttgag tcacgagttc agcaacaaga agatgaaatc 350

 actgtgctaa aggcggcttt ggctgatgtt ttgaggcgtc ttgcaatctc 400

 tgaagatcat gtggcctcag tgaaaaaatc agtctcaagt aaaggccaac 450

 caagccctcg agcagttatt cccatgtcct gtataaccaa tggaagtggt 500

 gcaaacagaa aaccaagtca taccagtgct gtctcaattg caggaaaaga 550

 aactctttca tctgctgcta aaagtggtac agaaaaaaag aaagaaaaac 600

 cacaaggaca gagagaaaaa aaagaggaat ctcattctaa tgatcaaagt 650

 ccacaaattc gagcatcacc ttctccccag ccctcttcac aacctctcca 700

 aatacacaga caaactccag aaagcaagaa tgctactccc accaaaagca 750

 taaaacgacc atcaccagct gaaaagtcac ataattcttg ggaaaattca 800

 gatgatagcc gtaataaatt gtcgaaaata ccttcaacac ccaaattaat 850

 accaaaagtt accaaaactg cagacaagca taaagatgtc atcatcaacc 900

 aagaaggaga atatattaaa atgtttatgc gcggtcggcc aattaccatg 950

 ttcattcctt ccgatgttga caactatgat gacatcagaa cggaactgcc 1000

 tcctgagaag ctcaaactgg agtgggcata tggttatcga ggaaaggact 1050

 gtagagctaa tgtttacctt cttccgaccg gggaaatagt ttatttcatt 1100

 gcatcagtag tagtactatt taattatgag gagagaactc agcgacacta 1150

 cctgggccat acagactgtg tgaaatgcct tgctatacat cctgacaaaa 1200

 ttaggattgc aactggacag atagctggcg tggataaaga tggaaggcct 1250

 ctacaacccc acgtcagagt gtgggattct gttactctat ccacactgca 1300

 gattattgga cttggcactt ttgagcgtgg agtaggatgc ctggattttt 1350

 caaaagcaga ttcaggtgtt catttatgtg ttattgatga ctccaatgag 1400

 catatgctta ctgtatggga ctggcagaag aaagcaaaag gagcagaaat 1450

 aaagacaaca aatgaagttg ttttggctgt ggagtttcac ccaacagatg 1500

 caaataccat aattacatgc ggtaaatctc atattttctt ctggacctgg 1550

 agcggcaatt cactaacaag aaaacaggga atttttggga aatatgaaaa 1600

 gccaaaattt gtgcagtgtt tagcattctt ggggaatgga gatgttctta 1650

 ctggagactc aggtggagtc atgcttatat ggagcaaaac tactgtagag 1700

 cccacacctg ggaaaggacc taaaggtgta tatcaaatca gcaaacaaat 1750

 caaagctcat gatggcagtg tgttcacact ttgtcagatg agaaatggga 1800

 tgttattaac tggaggaggg aaagacagaa aaataattct gtgggatcat 1850

 gatctgaatc ctgaaagaga aatagaggtt cctgatcagt atggcacaat 1900

 cagagctgta gcagaaggaa aggcagatca atttttagta ggcacatcac 1950

 gaaactttat tttacgagga acatttaatg atggcttcca aatagaagta 2000

 cagggtcata cagatgagct ttggggtctt gccacacatc ccttcaaaga 2050

 tttgctcttg acatgtgctc aggacaggca ggtgtgcctg tggaactcaa 2100

 tggaacacag gctggaatgg accaggctgg tagatgaacc aggacactgt 2150

 gcagattttc atccaagtgg cacagtggtg gccataggaa cgcactcagg 2200

 caggtggttt gttctggatg cagaaaccag agatctagtt tctatccaca 2250

 cagacgggaa tgaacagctc tctgtgatgc gctactcaat agatggtacc 2300

 ttcctggctg taggatctca tgacaacttt atttacctct atgtagtctc 2350

 tgaaaatgga agaaaatata gcagatatgg aaggtgcact ggacattcca 2400

 gctacatcac acaccttgac tggtccccag acaacaagta tataatgtct 2450

 aactcgggag actatgaaat attgtactgg gacattccaa atggctgcaa 2500

 actaatcagg aatcgatcgg attgtaagga cattgattgg acgacatata 2550

 cctgtgtgct aggatttcaa gtatttggtg tctggccaga aggatctgat 2600

 gggacagata tcaatgcact ggtgcgatcc cacaatagaa aggtgatagc 2650

 tgttgccgat gacttttgta aagtccatct gtttcagtat ccctgctcca 2700

 aagcaaaggc tcccagtcac aagtacagtg cccacagcag ccatgtcacc 2750

 aatgtcagtt ttactcacaa tgacagtcac ctgatatcaa ctggtggaaa 2800

 agacatgagc atcattcagt ggaaacttgt ggaaaagtta tctttgcctc 2850

 agaatgagac tgtagcggat actactctaa ccaaagcccc cgtctcttcc 2900

 actgaaagtg tcatccaatc taatactccc acaccgcctc cttctcagcc 2950

 cttaaatgag acagctgaag aggaaagtag aataagcagt tctcccacac 3000

 ttctggagaa cagcctggaa caaactgtgg agccaagtga agaccacagc 3050

 gaggaggaga gtgaagaggg cagcggagac cttggtgagc ctctttatga 3100

 agagccatgc aacgagataa gcaaggagca ggccaaagcc acccttctgg 3150

 aggaccagca agacccttcg ccctcgtcct aacaccctgg cttcagtgca 3200

 actcttttcc ttcagctgca tgtgattttg tgataaagtt caggtaacag 3250

 gatgggcagt gatggagaat cactgttgat tgagattttg gtttccatgt 3300

 gatttgtttt cttcaatagt cttattttca gtctctcaaa tacagccaac 3350

 ttaaagtttt agtttggtgt ttattgaaaa ttaaccaaac ttaatactag 3400

 gagaagactg aatcattaat gatgtctcac aaattactgt gtacctaagt 3450

 ggtgtgatgt aaatactgga aacaaaaaca gcagttgcat tgattttgaa 3500

 aacaaacccc cttgttatct gaacatgttt tcttcaggaa caaccagagg 3550

 tatcacaaac actgttactc atctactggc tcagactgta ctactttttt 3600

 tttttttttt cctgaaaaag aaaccagaaa aaaatgtact cttactgaga 3650

 taccctctca ccccaaatgt gtaatggaaa atttttaatt aagaaaaact 3700

 tcagttttgc caagtgcaat ggtgttgcct tctttaaaaa atgccgtttt 3750

 cttacactac cagtggatgt ccagacatgc tcttagtcta ctagagaggt 3800

 gctgcctttt ctaagtcata atgaggaaca gtcccttaat ttcttgtgtg 3850

 caactctgtt ttatcctaga actaagagag cattggtttg ttaaagagct 3900

 ttcaatgtat attaaaacct tcaatactca gaaatgatgg attcctccaa 3950

 ggagtccttt actagcctaa acattctcaa atgtttgaga ttcaagtgaa 4000

 tggaaggaaa accacatgcc tttaaaacta aactgtaata attacctggc 4050

 taatttcagc taagccttca tcataatttg ttccctcagt aataggagaa 4100

 atataaatac agtaagttta gattattgaa ttggtgcttg aaatttattg 4150

 gttttgttgt aattttatac agattatatg agggataaga tactcatcaa 4200

 attgcaaatt ctttttttta cagaagtgtg ggtaacagtc acagcagttt 4250

 tttttaccaa cagcatactt aacagacttg ctgtgtagca gtttttttct 4300

 ggtggagttg ctgtaagtct tgtaagtcta atgtggctat cctactcttt 4350

 tgggcaatgc atgtattatg cattggaaag gtattttttt taagttctgt 4400

 tggctagcta tggttttcag tacatttcct actttaagag taattactga 4450

 caaatatgta tttcctatat gtttatactt tgattataaa aaagtatttt 4500

 gttttgattt tttaacttgc tgcattgttt tgatactttc tatttttttg 4550

 gtcaaatcat gtttagaaac tttggatgag ttaagaagtc ttaagtatgc 4600

 aggcgtttac gtgattgtgc cattccaaag tgcatcagaa ctgtcattcc 4650

 cttctaatat cttctcagga gtaatacaaa tcaggtattt catcatcatt 4700

 tggtaatatg aaaactccag tgaactccca aggacattta caacatttat 4750

 attcacacgc tgtatggaag ggtgtgggtg tgtgtgaagg ggcgagtgga 4800

 gacactgtgt gtatctctag ataagaagat atgcaccacg ttgaaaatac 4850

 tcagtgtaga tctctatgtg tataggtatc tgtatatctt tccttttgtt 4900

 tacaactgtt aaaaaacctc aaaatagttc tcttcaaaag aagagagatt 4950

 ccaagcaacc catctttctt cagtatgtat gttctgtaca tacttatcgg 5000

 agcgcgccag taagtatcag gcatatatat ctgtctgtta gcaatgatta 5050

 ttacatcatc agatcagcat gtgctatact ccctgcaaga aatatactga 5100

 catgaacagg cagttcttgg agaagaaaga gcatttcttt aagtacctgg 5150

 ggaatacagc tctcagtgat cagcagggag tttatttgag gacatcagtc 5200

 acctttgggg ttgccatgta caatgagatt tataatcatg atactcttcg 5250

 gtggtagttt caaaagacac tactaatacg caggaagcgt tccagctatt 5300

 taatgctggc aactactgtt taatggtcag ttaaatctgt gataatggtt 5350

 ggaagtgggt ggggttatga aattgtagat gtttttagaa aaacttgtga 5400

 atgaaaatga atccaagtgt ttcatgtgaa gatgttgagc cattgctatc 5450

 atgcattcct gtctcatggc agaaaatttt gaagattaaa aaataaaata 5500

 atcaaaatgt ttcctctttc taaaaaaaaa aaaaaaaaa 5539

<210> 3826
<211> 981
<212> PRT
<213> Homo sapien

<400> 3826
 Met Asp Gly Phe Ala Gly Ser Leu Asp Asp Ser Ile Ser Ala Ala
   1               5                  10                  15

 Ser Thr Ser Asp Val Gln Asp Arg Leu Ser Ala Leu Glu Ser Arg
                  20                  25                  30

 Val Gln Gln Gln Glu Asp Glu Ile Thr Val Leu Lys Ala Ala Leu
                  35                  40                  45

 Ala Asp Val Leu Arg Arg Leu Ala Ile Ser Glu Asp His Val Ala
                  50                  55                  60

 Ser Val Lys Lys Ser Val Ser Ser Lys Gly Gln Pro Ser Pro Arg
                  65                  70                  75

 Ala Val Ile Pro Met Ser Cys Ile Thr Asn Gly Ser Gly Ala Asn
                  80                  85                  90

 Arg Lys Pro Ser His Thr Ser Ala Val Ser Ile Ala Gly Lys Glu
                  95                 100                 105

 Thr Leu Ser Ser Ala Ala Lys Ser Gly Thr Glu Lys Lys Lys Glu
                 110                 115                 120

 Lys Pro Gln Gly Gln Arg Glu Lys Lys Glu Glu Ser His Ser Asn
                 125                 130                 135

 Asp Gln Ser Pro Gln Ile Arg Ala Ser Pro Ser Pro Gln Pro Ser
                 140                 145                 150

 Ser Gln Pro Leu Gln Ile His Arg Gln Thr Pro Glu Ser Lys Asn
                 155                 160                 165

 Ala Thr Pro Thr Lys Ser Ile Lys Arg Pro Ser Pro Ala Glu Lys
                 170                 175                 180

 Ser His Asn Ser Trp Glu Asn Ser Asp Asp Ser Arg Asn Lys Leu
                 185                 190                 195

 Ser Lys Ile Pro Ser Thr Pro Lys Leu Ile Pro Lys Val Thr Lys
                 200                 205                 210

 Thr Ala Asp Lys His Lys Asp Val Ile Ile Asn Gln Glu Gly Glu
                 215                 220                 225

 Tyr Ile Lys Met Phe Met Arg Gly Arg Pro Ile Thr Met Phe Ile
                 230                 235                 240

 Pro Ser Asp Val Asp Asn Tyr Asp Asp Ile Arg Thr Glu Leu Pro
                 245                 250                 255

 Pro Glu Lys Leu Lys Leu Glu Trp Ala Tyr Gly Tyr Arg Gly Lys
                 260                 265                 270

 Asp Cys Arg Ala Asn Val Tyr Leu Leu Pro Thr Gly Glu Ile Val
                 275                 280                 285

 Tyr Phe Ile Ala Ser Val Val Val Leu Phe Asn Tyr Glu Glu Arg
                 290                 295                 300

 Thr Gln Arg His Tyr Leu Gly His Thr Asp Cys Val Lys Cys Leu
                 305                 310                 315

 Ala Ile His Pro Asp Lys Ile Arg Ile Ala Thr Gly Gln Ile Ala
                 320                 325                 330

 Gly Val Asp Lys Asp Gly Arg Pro Leu Gln Pro His Val Arg Val
                 335                 340                 345

 Trp Asp Ser Val Thr Leu Ser Thr Leu Gln Ile Ile Gly Leu Gly
                 350                 355                 360

 Thr Phe Glu Arg Gly Val Gly Cys Leu Asp Phe Ser Lys Ala Asp
                 365                 370                 375

 Ser Gly Val His Leu Cys Val Ile Asp Asp Ser Asn Glu His Met
                 380                 385                 390

 Leu Thr Val Trp Asp Trp Gln Lys Lys Ala Lys Gly Ala Glu Ile
                 395                 400                 405

 Lys Thr Thr Asn Glu Val Val Leu Ala Val Glu Phe His Pro Thr
                 410                 415                 420

 Asp Ala Asn Thr Ile Ile Thr Cys Gly Lys Ser His Ile Phe Phe
                 425                 430                 435

 Trp Thr Trp Ser Gly Asn Ser Leu Thr Arg Lys Gln Gly Ile Phe
                 440                 445                 450

 Gly Lys Tyr Glu Lys Pro Lys Phe Val Gln Cys Leu Ala Phe Leu
                 455                 460                 465

 Gly Asn Gly Asp Val Leu Thr Gly Asp Ser Gly Gly Val Met Leu
                 470                 475                 480

 Ile Trp Ser Lys Thr Thr Val Glu Pro Thr Pro Gly Lys Gly Pro
                 485                 490                 495

 Lys Gly Val Tyr Gln Ile Ser Lys Gln Ile Lys Ala His Asp Gly
                 500                 505                 510

 Ser Val Phe Thr Leu Cys Gln Met Arg Asn Gly Met Leu Leu Thr
                 515                 520                 525

 Gly Gly Gly Lys Asp Arg Lys Ile Ile Leu Trp Asp His Asp Leu
                 530                 535                 540

 Asn Pro Glu Arg Glu Ile Glu Val Pro Asp Gln Tyr Gly Thr Ile
                 545                 550                 555

 Arg Ala Val Ala Glu Gly Lys Ala Asp Gln Phe Leu Val Gly Thr
                 560                 565                 570

 Ser Arg Asn Phe Ile Leu Arg Gly Thr Phe Asn Asp Gly Phe Gln
                 575                 580                 585

 Ile Glu Val Gln Gly His Thr Asp Glu Leu Trp Gly Leu Ala Thr
                 590                 595                 600

 His Pro Phe Lys Asp Leu Leu Leu Thr Cys Ala Gln Asp Arg Gln
                 605                 610                 615

 Val Cys Leu Trp Asn Ser Met Glu His Arg Leu Glu Trp Thr Arg
                 620                 625                 630

 Leu Val Asp Glu Pro Gly His Cys Ala Asp Phe His Pro Ser Gly
                 635                 640                 645

 Thr Val Val Ala Ile Gly Thr His Ser Gly Arg Trp Phe Val Leu
                 650                 655                 660

 Asp Ala Glu Thr Arg Asp Leu Val Ser Ile His Thr Asp Gly Asn
                 665                 670                 675

 Glu Gln Leu Ser Val Met Arg Tyr Ser Ile Asp Gly Thr Phe Leu
                 680                 685                 690

 Ala Val Gly Ser His Asp Asn Phe Ile Tyr Leu Tyr Val Val Ser
                 695                 700                 705

 Glu Asn Gly Arg Lys Tyr Ser Arg Tyr Gly Arg Cys Thr Gly His
                 710                 715                 720

 Ser Ser Tyr Ile Thr His Leu Asp Trp Ser Pro Asp Asn Lys Tyr
                 725                 730                 735

 Ile Met Ser Asn Ser Gly Asp Tyr Glu Ile Leu Tyr Trp Asp Ile
                 740                 745                 750

 Pro Asn Gly Cys Lys Leu Ile Arg Asn Arg Ser Asp Cys Lys Asp
                 755                 760                 765

 Ile Asp Trp Thr Thr Tyr Thr Cys Val Leu Gly Phe Gln Val Phe
                 770                 775                 780

 Gly Val Trp Pro Glu Gly Ser Asp Gly Thr Asp Ile Asn Ala Leu
                 785                 790                 795

 Val Arg Ser His Asn Arg Lys Val Ile Ala Val Ala Asp Asp Phe
                 800                 805                 810

 Cys Lys Val His Leu Phe Gln Tyr Pro Cys Ser Lys Ala Lys Ala
                 815                 820                 825

 Pro Ser His Lys Tyr Ser Ala His Ser Ser His Val Thr Asn Val
                 830                 835                 840

 Ser Phe Thr His Asn Asp Ser His Leu Ile Ser Thr Gly Gly Lys
                 845                 850                 855

 Asp Met Ser Ile Ile Gln Trp Lys Leu Val Glu Lys Leu Ser Leu
                 860                 865                 870

 Pro Gln Asn Glu Thr Val Ala Asp Thr Thr Leu Thr Lys Ala Pro
                 875                 880                 885

 Val Ser Ser Thr Glu Ser Val Ile Gln Ser Asn Thr Pro Thr Pro
                 890                 895                 900

 Pro Pro Ser Gln Pro Leu Asn Glu Thr Ala Glu Glu Glu Ser Arg
                 905                 910                 915

 Ile Ser Ser Ser Pro Thr Leu Leu Glu Asn Ser Leu Glu Gln Thr
                 920                 925                 930

 Val Glu Pro Ser Glu Asp His Ser Glu Glu Glu Ser Glu Glu Gly
                 935                 940                 945

 Ser Gly Asp Leu Gly Glu Pro Leu Tyr Glu Glu Pro Cys Asn Glu
                 950                 955                 960

 Ile Ser Lys Glu Gln Ala Lys Ala Thr Leu Leu Glu Asp Gln Gln
                 965                 970                 975

 Asp Pro Ser Pro Ser Ser
                 980

<210> 3827
<211> 1183
<212> DNA
<213> Homo sapien

<400> 3827
 gttctgcccg gatggaagct ccggccgcgg agtgatggtg gcctcagcga 50

 agatgggccg ggcagggacc atggcggtgg cagcagaggt ggcaggggcg 100

 gggcggctgg cggtagagga ggctgtggtc ctcagggggc tgtaggtgga 150

 ggtatggctc gggccagcag cgggaacggc agcgaggagg cctggggggc 200

 acttcgggcg ccgcaacagc agcttcgaga gctgtgccca ggagtgaaca 250

 accagcccta cctctgtgag agtggtcact gctgcgggga gactggctgc 300

 tgcacctact actatgagct ctggtggttc tggctgctct ggactgtcct 350

 catcctcttt agctgctgtt gcgccttccg ccaccgacga gctaaactca 400

 ggctgcaaca acagcagcgg cagcgtgaaa tcaacttgtt ggcctatcat 450

 ggggcatgcc atggggctgg tcctttccct accggttcac tgcttgacct 500

 tcgcttcctc agcaccttca agcccccagc ctacgaggat gtggttcacc 550

 gcccaggcac accacccccc ccttatactg tggccccagg ccgccccttg 600

 actgcttcca gtgaacaaac ctgctgttcc tcctcatcca gctgccctgc 650

 ccactttgaa ggaacaaatg tggaaggtgt ttcctcccac cagagtgccc 700

 cccctcatca ggagggtgag cccggggcag gggtgacccc tgcctccaca 750

 cccccctcct gccgctatcg ccgtttaact ggcgactccg gtattgagct 800

 ctgcccttgt cctgcctccg gtgagggtga gccagtcaag gaggtgaggg 850

 ttagtgccac cctgccagat ctggaggact actccccgtg tgcactaccc 900

 ccagagtctg taccgcagat ctttcccatg gggctgtctt ccagtgaagg 950

 ggacatccca taagtagttt tgagagggtg gatgggttac ttgcccacca 1000

 gaaacagccc tagtcccaac tccttgcgtt cctttggccc ctccctgcct 1050

 acctagaatc tgcctgaaag ggctggagag gggcagtatt gggggactgt 1100

 gctagcttta cccccgcagg acatacacag gagcctttga tctcattaaa 1150

 gagatgtgaa ccagcaaaaa aaaaaaaaaa aaa 1183

<210> 3828
<211> 269
<212> PRT
<213> Homo sapien

<400> 3828
 Met Ala Arg Ala Ser Ser Gly Asn Gly Ser Glu Glu Ala Trp Gly
   1               5                  10                  15

 Ala Leu Arg Ala Pro Gln Gln Gln Leu Arg Glu Leu Cys Pro Gly
                  20                  25                  30

 Val Asn Asn Gln Pro Tyr Leu Cys Glu Ser Gly His Cys Cys Gly
                  35                  40                  45

 Glu Thr Gly Cys Cys Thr Tyr Tyr Tyr Glu Leu Trp Trp Phe Trp
                  50                  55                  60

 Leu Leu Trp Thr Val Leu Ile Leu Phe Ser Cys Cys Cys Ala Phe
                  65                  70                  75

 Arg His Arg Arg Ala Lys Leu Arg Leu Gln Gln Gln Gln Arg Gln
                  80                  85                  90

 Arg Glu Ile Asn Leu Leu Ala Tyr His Gly Ala Cys His Gly Ala
                  95                 100                 105

 Gly Pro Phe Pro Thr Gly Ser Leu Leu Asp Leu Arg Phe Leu Ser
                 110                 115                 120

 Thr Phe Lys Pro Pro Ala Tyr Glu Asp Val Val His Arg Pro Gly
                 125                 130                 135

 Thr Pro Pro Pro Pro Tyr Thr Val Ala Pro Gly Arg Pro Leu Thr
                 140                 145                 150

 Ala Ser Ser Glu Gln Thr Cys Cys Ser Ser Ser Ser Ser Cys Pro
                 155                 160                 165

 Ala His Phe Glu Gly Thr Asn Val Glu Gly Val Ser Ser His Gln
                 170                 175                 180

 Ser Ala Pro Pro His Gln Glu Gly Glu Pro Gly Ala Gly Val Thr
                 185                 190                 195

 Pro Ala Ser Thr Pro Pro Ser Cys Arg Tyr Arg Arg Leu Thr Gly
                 200                 205                 210

 Asp Ser Gly Ile Glu Leu Cys Pro Cys Pro Ala Ser Gly Glu Gly
                 215                 220                 225

 Glu Pro Val Lys Glu Val Arg Val Ser Ala Thr Leu Pro Asp Leu
                 230                 235                 240

 Glu Asp Tyr Ser Pro Cys Ala Leu Pro Pro Glu Ser Val Pro Gln
                 245                 250                 255

 Ile Phe Pro Met Gly Leu Ser Ser Ser Glu Gly Asp Ile Pro
                 260                 265

<210> 3829
<211> 2427
<212> DNA
<213> Homo sapien

<400> 3829
 gggatttgtt attgcgaatg atgtggacaa caagcgctgc tacctgctcg 50

 tccatcaagc caagaggctg agcagcccct gcatcatggt ggtcaaccat 100

 gatgcctcca gcatacccag gctccagata gatgtggacg gcaggaaaga 150

 gatcctcttc tatgatcgaa ttttatgtga tgtcccttgc agtggagacg 200

 gcactatgag aaaaaacatt gatgtttgga aaaagtggac caccttaaat 250

 agcttgcagc tacatggctt acagctgcgg attgcaacac gcggggctga 300

 acagctggct gaaggtggaa gggtggtgta ttccacgtgt tcactaaacc 350

 ctattgagga tgaagcagtc atagcatctt tactggaaaa aagtgaaggt 400

 gctttggagc ttgctgatgt gtctaatgaa ctgccagggc tgaagtggat 450

 gcctggaatc acacagtgga aggtaatgac gaaagatggg cagtggttta 500

 cagactggga cgctgttcct cacagcagac acacccagat ccgacctacc 550

 atgttccctc cgaaggaccc agaaaagctg caggccatgc acctggagcg 600

 atgccttagg atattacccc atcatcagaa tactggaggg ttttttgtgg 650

 cagtattggt gaaaaaatct tcaatgccgt ggaataaacg tcagccaaag 700

 cttcagggta aatctgcaga gaccagagaa agcacacagc tgagccctgc 750

 agatctcaca gaagggaaac ccacagatcc ctctaagctg gaaagtccgt 800

 cattcacagg aactggtgac acagaaatag ctcatgcaac tgaggattta 850

 gagaataatg gcagtaagaa agatggcgtg tgtggtcctc ctccatcaaa 900

 gaaaatgaag ttatttggat ttaaagaaga tccatttgta tttattcctg 950

 aagatgaccc attatttcca cctattgaga aattttatgc tttggatcct 1000

 tcattcccaa ggatgaattt gttaactcgg actacagaag ggaagaaaag 1050

 gcagctctac atggtttcta aggagttgcg gaatgtgctg ctgaataaca 1100

 gtgagaagat gaaggttatt aacacgggga tcaaagtctg gtgtagaaat 1150

 aacagcggtg aagagtttga ctgtgctttc cggctggcac aggagggaat 1200

 atatacattg tatccattta ttaactcaag aattattact gtatcaatgg 1250

 aagatgttaa gatactgttg acccaggaaa atcccttttt tagaaaactc 1300

 agcagtgaga cctacagtca agcaaaggac ctggcaaagg gaagcatcgt 1350

 gctgaagtat gaaccagatt ctgcgaatcc agacgctcta cagtgtccca 1400

 tcgtcttatg cggatggcgg ggaaaggcct ccattcgaac ttttgtgccc 1450

 aagaatgaac ggcttcacta tctcaggatg atggggctgg aggtattggg 1500

 agaaaagaag aaggaagggg ttatcctcac aaatgagagt gcagccagca 1550

 ccggacagcc agacaatgac gtgactgagg gacagagagc aggagagccc 1600

 aacagcccag atgcagaaga ggccaacagt ccagacgtga cagcaggctg 1650

 tgacccggcg ggggtccatc caccccggtg agcaggccca aggcagcggg 1700

 ggcccacacc cctcacacgc aaaactggct tcttctggtc actggtgtct 1750

 gaaaccaaat ccagagcagc ctgtggcctg taaagcatat atttctagtg 1800

 actgcagact ggtgggatca taggagcctt ctgaatgacc aggactgctt 1850

 tctttggagc tgatgaaaat gtactctttt agcgtgttag aaatcacttg 1900

 ttttattttg ttttctttgg ccaagctggg tctagtgttt cttttgctgg 1950

 gaatagactt tcaaaagttg tacttctatc aagaaacaaa actgcccttg 2000

 cagaaatttc aggtcttttg ttaagcctgt attggtctta aggtgcagta 2050

 ttttttaaat tattatttat agaaagaatc tataaattct tggggaagtg 2100

 tgttataagc tttaataatt acattgagct gcacctcagt ggtgtgtcat 2150

 taacatgcag tggggttaat atctgaggcc tcagatgact ttgtgccttt 2200

 tggaataaag ggtaaaataa actctcccag agtaagagct gtatcgtgaa 2250

 ttgtcatact aattattgag ggggacttat gtgcttttat tgaatggagt 2300

 gctttacaat ttttattttt aaatggggtt gggatccttg gaatatttca 2350

 ataaaattga taaaatataa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2400

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 2427

<210> 3830
<211> 531
<212> PRT
<213> Homo sapien

<400> 3830
 Met Val Val Asn His Asp Ala Ser Ser Ile Pro Arg Leu Gln Ile
   1               5                  10                  15

 Asp Val Asp Gly Arg Lys Glu Ile Leu Phe Tyr Asp Arg Ile Leu
                  20                  25                  30

 Cys Asp Val Pro Cys Ser Gly Asp Gly Thr Met Arg Lys Asn Ile
                  35                  40                  45

 Asp Val Trp Lys Lys Trp Thr Thr Leu Asn Ser Leu Gln Leu His
                  50                  55                  60

 Gly Leu Gln Leu Arg Ile Ala Thr Arg Gly Ala Glu Gln Leu Ala
                  65                  70                  75

 Glu Gly Gly Arg Val Val Tyr Ser Thr Cys Ser Leu Asn Pro Ile
                  80                  85                  90

 Glu Asp Glu Ala Val Ile Ala Ser Leu Leu Glu Lys Ser Glu Gly
                  95                 100                 105

 Ala Leu Glu Leu Ala Asp Val Ser Asn Glu Leu Pro Gly Leu Lys
                 110                 115                 120

 Trp Met Pro Gly Ile Thr Gln Trp Lys Val Met Thr Lys Asp Gly
                 125                 130                 135

 Gln Trp Phe Thr Asp Trp Asp Ala Val Pro His Ser Arg His Thr
                 140                 145                 150

 Gln Ile Arg Pro Thr Met Phe Pro Pro Lys Asp Pro Glu Lys Leu
                 155                 160                 165

 Gln Ala Met His Leu Glu Arg Cys Leu Arg Ile Leu Pro His His
                 170                 175                 180

 Gln Asn Thr Gly Gly Phe Phe Val Ala Val Leu Val Lys Lys Ser
                 185                 190                 195

 Ser Met Pro Trp Asn Lys Arg Gln Pro Lys Leu Gln Gly Lys Ser
                 200                 205                 210

 Ala Glu Thr Arg Glu Ser Thr Gln Leu Ser Pro Ala Asp Leu Thr
                 215                 220                 225

 Glu Gly Lys Pro Thr Asp Pro Ser Lys Leu Glu Ser Pro Ser Phe
                 230                 235                 240

 Thr Gly Thr Gly Asp Thr Glu Ile Ala His Ala Thr Glu Asp Leu
                 245                 250                 255

 Glu Asn Asn Gly Ser Lys Lys Asp Gly Val Cys Gly Pro Pro Pro
                 260                 265                 270

 Ser Lys Lys Met Lys Leu Phe Gly Phe Lys Glu Asp Pro Phe Val
                 275                 280                 285

 Phe Ile Pro Glu Asp Asp Pro Leu Phe Pro Pro Ile Glu Lys Phe
                 290                 295                 300

 Tyr Ala Leu Asp Pro Ser Phe Pro Arg Met Asn Leu Leu Thr Arg
                 305                 310                 315

 Thr Thr Glu Gly Lys Lys Arg Gln Leu Tyr Met Val Ser Lys Glu
                 320                 325                 330

 Leu Arg Asn Val Leu Leu Asn Asn Ser Glu Lys Met Lys Val Ile
                 335                 340                 345

 Asn Thr Gly Ile Lys Val Trp Cys Arg Asn Asn Ser Gly Glu Glu
                 350                 355                 360

 Phe Asp Cys Ala Phe Arg Leu Ala Gln Glu Gly Ile Tyr Thr Leu
                 365                 370                 375

 Tyr Pro Phe Ile Asn Ser Arg Ile Ile Thr Val Ser Met Glu Asp
                 380                 385                 390

 Val Lys Ile Leu Leu Thr Gln Glu Asn Pro Phe Phe Arg Lys Leu
                 395                 400                 405

 Ser Ser Glu Thr Tyr Ser Gln Ala Lys Asp Leu Ala Lys Gly Ser
                 410                 415                 420

 Ile Val Leu Lys Tyr Glu Pro Asp Ser Ala Asn Pro Asp Ala Leu
                 425                 430                 435

 Gln Cys Pro Ile Val Leu Cys Gly Trp Arg Gly Lys Ala Ser Ile
                 440                 445                 450

 Arg Thr Phe Val Pro Lys Asn Glu Arg Leu His Tyr Leu Arg Met
                 455                 460                 465

 Met Gly Leu Glu Val Leu Gly Glu Lys Lys Lys Glu Gly Val Ile
                 470                 475                 480

 Leu Thr Asn Glu Ser Ala Ala Ser Thr Gly Gln Pro Asp Asn Asp
                 485                 490                 495

 Val Thr Glu Gly Gln Arg Ala Gly Glu Pro Asn Ser Pro Asp Ala
                 500                 505                 510

 Glu Glu Ala Asn Ser Pro Asp Val Thr Ala Gly Cys Asp Pro Ala
                 515                 520                 525

 Gly Val His Pro Pro Arg
                 530

<210> 3831
<211> 4438
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 312, 3415, 3451, 3671, 3880
<223> Unknown base

<400> 3831
 gcggccgctg aattctaggg cggagcgaag agaaccggtc gcggcaatcc 50

 tagcgcgcag cagcagcagc agcagcagca cccgcatccg ctgcgggagt 100

 ccgagccgga accacaccca agtagctgcc ctttcctctt ctgtcatctc 150

 accgccccac cacagaccgc gttccccgag gaaaccggcc gcccacgccc 200

 ggagcatcct cccctgttga gcgggcgctg acggacccgg cggcatgatg 250

 cggctgcgag gctcggggat gctgcgggac ctgctcctgc ggtcgcccgc 300

 cggcgtgagc gngactctgc ggcgggcaca gcccttggtc accctgtgcc 350

 ggcgtccccg aggcggggga cggccggccg cgggcccggc tgccgccgcg 400

 cgactccacc cgtggtgggg cgggggcggc tggccggcgg agcccctcgc 450

 gcggggcctg tccagctctc cttcggagat cttgcaggag ctgggcaagg 500

 ggagcacgca tccccagccc ggggtgtcgc cacccgctgc cccggcggcg 550

 cccggcccca aggacggccc cggggagacg gacgcgtttg gcaacagcga 600

 gggcaaagag ctggtggcct caggtgaaaa caaaataaaa cagggtctgt 650

 tacctagctt ggaagatttg ctgttctata caattgctga aggacaagag 700

 aaaatacctg ttcataaatt tattacagca ctcaaatcta caggattgcg 750

 aacgtctgat cccaggttga aagagtgtat ggatatgtta agattaactc 800

 ttcaaacaac atcagatggt gtcatgctag acaaagatct ttttaaaaaa 850

 tgtgttcaga gcaacattgt tttgttgaca caagcattta gaagaaagtt 900

 tgtgattcct gactttatgt cttttacctc acacattgat gagttatatg 950

 aaagtgctaa aaagcagtct ggaggaaagg ttgcagatta tattcctcaa 1000

 ctggccaaat tcagtcccga tttgtggggt gtgtctgttt gtacagcaga 1050

 tggacagagg cattctactg gagataccaa agttcccttc tgtcttcagt 1100

 cctgtgtaaa acctttgaaa tatgccattg ctgttaatga tcttggaact 1150

 gaatatgtgc atcgatatgt tggaaaagag ccgagtggac taagattcaa 1200

 caaactattt ttgaatgaag atgataaacc acataatcct atggtaaatg 1250

 ctggagcaat tgttgtgact tcactaataa agcaaggagt aaataatgct 1300

 gaaaaatttg actatgtcat gcagtttttg aataagatgg ctggtaatga 1350

 atatgttgga ttcagtaatg caacgtttca gtctgaaaga gaaagtggag 1400

 atcgaaattt tgcaatagga tattacttaa aagaaaagaa gtgttttcca 1450

 gaaggcacag acatggttgg tatattagac ttctacttcc agctgtgctc 1500

 cattgaagtg acttgtgaat cagccagtgt gatggctgcg acactggcta 1550

 atggtggttt ctgcccaatt actggtgaaa gagtactgag ccctgaagca 1600

 gttcgaaata cattgagttt gatgcattcc tgtggcatgt atgacttctc 1650

 agggcagttt gctttccatg ttggtcttcc tgcaaaatct ggagttgctg 1700

 ggggcattct tttagttgtc cccaatgtta tgggtatgat gtgctggtct 1750

 cctcctctgg ataagatggg caacagtgtt aagggaattc acttttgtca 1800

 cgatcttgtt tctctgtgta atttccataa ctatgataat ttgagacact 1850

 ttgcaaaaaa acttgatcct cgaagagaag gtggtgatca aaggcattcc 1900

 tttggaccat tggactatga aagtctccaa caagaacttg ctttaaaaga 1950

 gacagtatgg aaaaaagtgt cacctgagtc aaatgaggac atctctacaa 2000

 ctgtagtata tagaatggaa agtctgggag agaaaagcta aagaaatggg 2050

 ttctagtttc agaatgtttc ttcatttaat ctttcaaaca tctttagctt 2100

 ttttttgcaa gttataaata tttatttgag gtattttttg ttctcaatct 2150

 tgggtgctgg agccataaag cttttttttc cttttaatct ttgtataaag 2200

 gcagtagatt aagaagtgca tttgttggtc tttaaaaagt atttacaagt 2250

 acataaattt gctttatttt taaaaataca aaaaggaaaa atttaaattt 2300

 tttttgatgt aattaaaatg ttaactatgt ggtcagataa tcccatttta 2350

 caatagtaac agaaaattgt aattcttagt tctaaaattc acaaattaaa 2400

 ctcataagct ttgttgcatt ttgttttttc ttttccattt ttaaaactaa 2450

 tgtgatgtct ttagtggcaa tagaaggtac ttctatgcta aatacaaaac 2500

 taaaaaggca aaataatgaa ccccaaatta ttttatttaa aatagcagtg 2550

 gattataaaa ttagcttgtg tttacattta tgccattttt ggtgatagat 2600

 tggctttaca ttttaaaaaa tttatttaaa aatttatcaa atgctttaaa 2650

 atatgactcc tacttttttt attttgcaac tcctctgttc tgtcagagtt 2700

 gttatataca ggagtgtctt atgttactaa aacattccag ccaaagaatt 2750

 tcagatgtga gataatgatg tttcatcaat aaaaagctat aatggttagt 2800

 tactcagaag gagaaacagt gagtgtcttc aagtgaattg ttcacctaaa 2850

 caattttatt ttcatattat ccacataact ttttctatgt tatatttaaa 2900

 tatgaatggc aaattttggt ttttagcttt tacattttat tatcttaatt 2950

 ttataaatgc taatatttct tttgtgataa gttatagcat ctcataaagt 3000

 ttgttctatt tgaagttttt tagagtactt gagaaatgaa tttagtctgc 3050

 aggtagtaag tatgctacta aaatacgtta gatctaaatc cttttatttg 3100

 gtataaaaat gcaatattga gaatcaaaac ttgtttttaa gagaactata 3150

 gattctacac aacctgattt caagtaatta ttcatagtat ttatagttgt 3200

 cttggcaaag tgattgtaaa attctgtagg acctattcac acttcttcct 3250

 tcttccatat acttctctgg ttttccccat agttccccta taatttcaag 3300

 tttgttgaaa cctgttaatt ttagtggggg attagaagaa aaacttggtg 3350

 gtttcttagc atgatggtgt atgtatgtgg taatggaaag tctgtaaaag 3400

 taaatatagt gtagnaaaaa agatttcact gagtatttta gatactagtg 3450

 naaataaaga tagaaaatct tgatcataat gtcttaagtt tgggaactgt 3500

 gatattaaga aaagaaattc ccttctagag gtgctggcca aaaagccttt 3550

 tgggctaact taagtattaa atttatatat ttaaataatt atattttaag 3600

 ttgtagagga ttttcccaag gattttatgc ttacttgaat gttctttgaa 3650

 tgttcagatg catatcctaa nctggatgct tctcaaggcc ttactgcata 3700

 tttgtgttgc atatttatgt tagttgcacc agggccattt gtagtttggg 3750

 caaccgaatg ccttaattgg aaaaaaggca ttgtggtttc ccctattatc 3800

 taaattgtta cattttacca tttcattccg aagttggttt tactttatta 3850

 aatgaagatt tagttttcat atcgtatacn tagctgtata gatttcaaaa 3900

 ttaggttgtt aatttgtgtc acttactatt tttgtgttgg taatgcttta 3950

 aatgcatact taaaaatgaa gtactgttat ctaagctact gtgtttagaa 4000

 aatgttaaga atgagcagaa atttttatag aaaagataaa cggaagaaga 4050

 gataagatac tgcgaatagg ccctcaaact taaaaaagaa aaaactttgc 4100

 cagttttaag gacatatttt gattctttca gtatcttaac acctttttaa 4150

 acaaagttct tgatagtacc actattattg ggtttgtttt atgccattat 4200

 tgattcttga tattcaagca tttacaatgt agcatatttg attttctttt 4250

 ttctttcttt ttttggcatg tttttagcat aaatgttgca ttttatctta 4300

 gtgtttggat gaaaacattt gtgttgttta gctttcattt gctttgtata 4350

 tttaataatg tacctttatt ttccagtatg cctacatttt gtattgcaca 4400

 ataaatttat tttaagctga aaaaaaaaaa aaaaaaaa 4438

<210> 3832
<211> 598
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 23
<223> unknown amino acid

<220>
<221> Unsure
<222> 312, 3415, 3451, 3671, 3880
<223> Unknown amino acid

<400> 3832
 Met Met Arg Leu Arg Gly Ser Gly Met Leu Arg Asp Leu Leu Leu
   1               5                  10                  15

 Arg Ser Pro Ala Gly Val Ser Xaa Thr Leu Arg Arg Ala Gln Pro
                  20                  25                  30

 Leu Val Thr Leu Cys Arg Arg Pro Arg Gly Gly Gly Arg Pro Ala
                  35                  40                  45

 Ala Gly Pro Ala Ala Ala Ala Arg Leu His Pro Trp Trp Gly Gly
                  50                  55                  60

 Gly Gly Trp Pro Ala Glu Pro Leu Ala Arg Gly Leu Ser Ser Ser
                  65                  70                  75

 Pro Ser Glu Ile Leu Gln Glu Leu Gly Lys Gly Ser Thr His Pro
                  80                  85                  90

 Gln Pro Gly Val Ser Pro Pro Ala Ala Pro Ala Ala Pro Gly Pro
                  95                 100                 105

 Lys Asp Gly Pro Gly Glu Thr Asp Ala Phe Gly Asn Ser Glu Gly
                 110                 115                 120

 Lys Glu Leu Val Ala Ser Gly Glu Asn Lys Ile Lys Gln Gly Leu
                 125                 130                 135

 Leu Pro Ser Leu Glu Asp Leu Leu Phe Tyr Thr Ile Ala Glu Gly
                 140                 145                 150

 Gln Glu Lys Ile Pro Val His Lys Phe Ile Thr Ala Leu Lys Ser
                 155                 160                 165

 Thr Gly Leu Arg Thr Ser Asp Pro Arg Leu Lys Glu Cys Met Asp
                 170                 175                 180

 Met Leu Arg Leu Thr Leu Gln Thr Thr Ser Asp Gly Val Met Leu
                 185                 190                 195

 Asp Lys Asp Leu Phe Lys Lys Cys Val Gln Ser Asn Ile Val Leu
                 200                 205                 210

 Leu Thr Gln Ala Phe Arg Arg Lys Phe Val Ile Pro Asp Phe Met
                 215                 220                 225

 Ser Phe Thr Ser His Ile Asp Glu Leu Tyr Glu Ser Ala Lys Lys
                 230                 235                 240

 Gln Ser Gly Gly Lys Val Ala Asp Tyr Ile Pro Gln Leu Ala Lys
                 245                 250                 255

 Phe Ser Pro Asp Leu Trp Gly Val Ser Val Cys Thr Ala Asp Gly
                 260                 265                 270

 Gln Arg His Ser Thr Gly Asp Thr Lys Val Pro Phe Cys Leu Gln
                 275                 280                 285

 Ser Cys Val Lys Pro Leu Lys Tyr Ala Ile Ala Val Asn Asp Leu
                 290                 295                 300

 Gly Thr Glu Tyr Val His Arg Tyr Val Gly Lys Glu Pro Ser Gly
                 305                 310                 315

 Leu Arg Phe Asn Lys Leu Phe Leu Asn Glu Asp Asp Lys Pro His
                 320                 325                 330

 Asn Pro Met Val Asn Ala Gly Ala Ile Val Val Thr Ser Leu Ile
                 335                 340                 345

 Lys Gln Gly Val Asn Asn Ala Glu Lys Phe Asp Tyr Val Met Gln
                 350                 355                 360

 Phe Leu Asn Lys Met Ala Gly Asn Glu Tyr Val Gly Phe Ser Asn
                 365                 370                 375

 Ala Thr Phe Gln Ser Glu Arg Glu Ser Gly Asp Arg Asn Phe Ala
                 380                 385                 390

 Ile Gly Tyr Tyr Leu Lys Glu Lys Lys Cys Phe Pro Glu Gly Thr
                 395                 400                 405

 Asp Met Val Gly Ile Leu Asp Phe Tyr Phe Gln Leu Cys Ser Ile
                 410                 415                 420

 Glu Val Thr Cys Glu Ser Ala Ser Val Met Ala Ala Thr Leu Ala
                 425                 430                 435

 Asn Gly Gly Phe Cys Pro Ile Thr Gly Glu Arg Val Leu Ser Pro
                 440                 445                 450

 Glu Ala Val Arg Asn Thr Leu Ser Leu Met His Ser Cys Gly Met
                 455                 460                 465

 Tyr Asp Phe Ser Gly Gln Phe Ala Phe His Val Gly Leu Pro Ala
                 470                 475                 480

 Lys Ser Gly Val Ala Gly Gly Ile Leu Leu Val Val Pro Asn Val
                 485                 490                 495

 Met Gly Met Met Cys Trp Ser Pro Pro Leu Asp Lys Met Gly Asn
                 500                 505                 510

 Ser Val Lys Gly Ile His Phe Cys His Asp Leu Val Ser Leu Cys
                 515                 520                 525

 Asn Phe His Asn Tyr Asp Asn Leu Arg His Phe Ala Lys Lys Leu
                 530                 535                 540

 Asp Pro Arg Arg Glu Gly Gly Asp Gln Arg His Ser Phe Gly Pro
                 545                 550                 555

 Leu Asp Tyr Glu Ser Leu Gln Gln Glu Leu Ala Leu Lys Glu Thr
                 560                 565                 570

 Val Trp Lys Lys Val Ser Pro Glu Ser Asn Glu Asp Ile Ser Thr
                 575                 580                 585

 Thr Val Val Tyr Arg Met Glu Ser Leu Gly Glu Lys Ser
                 590                 595

<210> 3833
<211> 1129
<212> DNA
<213> Homo sapien

<400> 3833
 tggcaccggc atcggctgac actgctgcct ccagctagtt atttcgtcct 50

 cttccgttct tcacccctac accttggagg tgaacttctc acctgagggc 100

 tgtaaagact cgtttgaaaa tggagagcca agaaccaacg gaatcttctc 150

 agaatggcaa acagtatatc atttcagagg agttaatttc agaaggaaaa 200

 tgggtcaagc ttgaaaaaac aacgtacatg gatcctactg gtaaaactag 250

 aacttgggaa tcagtgaacg taccaaccag gaaagagcag actgcggatg 300

 gtgtcgcggt catccccgtg ctgcagagaa cacttcacta tgagtgtatc 350

 gttctggtga aacagttccg accaccaatg gggggctact gcatagagtt 400

 ccctgcaggt ctcatagatg atggtgaaac cccagaagca gctgctctcc 450

 gggagcttga agaagaaact ggctacaaag gggacattgc cgaatgttct 500

 ccagcggtct gtatggaccc aggcttgtca aactgtacta tacacatcgt 550

 gacagtcacc attaacggag atgatgccga aaacgcaagg ccgaagccaa 600

 agccagggga tggagagttt gtggaagtca tttctttacc caagaatgac 650

 ctgctgcaga gacttgatgc tctggtagct gaagaacatc tcacagtgga 700

 cgccagggtc tattcctacg ctctagcgct gaaacatgca aatgcaaagc 750

 catttgaagt gcccttcttg aaattttaag cccaaatatg acactggcca 800

 tttttgtaaa cgagaccacc aggccttctt cactaagact ttgtattcaa 850

 cttagtttaa tgtagatttg ccattagctt tttcgtaaaa taaaagcaca 900

 gaacagatgt ggtggtggta tggaattgta attacaggta ggttgtgacc 950

 ttcctttaaa tttgttataa ctccagctaa aattaacaaa gaatataaat 1000

 gcaagtatgt ttactccaat ttttttaaag ctcaacagag ttaactacag 1050

 ctcagttact tttctagtcc agtctggaac acaggggtat ttggtattga 1100

 gaaatagacc tgagttctca attaggtca 1129

<210> 3834
<211> 219
<212> PRT
<213> Homo sapien

<400> 3834
 Met Glu Ser Gln Glu Pro Thr Glu Ser Ser Gln Asn Gly Lys Gln
   1               5                  10                  15

 Tyr Ile Ile Ser Glu Glu Leu Ile Ser Glu Gly Lys Trp Val Lys
                  20                  25                  30

 Leu Glu Lys Thr Thr Tyr Met Asp Pro Thr Gly Lys Thr Arg Thr
                  35                  40                  45

 Trp Glu Ser Val Asn Val Pro Thr Arg Lys Glu Gln Thr Ala Asp
                  50                  55                  60

 Gly Val Ala Val Ile Pro Val Leu Gln Arg Thr Leu His Tyr Glu
                  65                  70                  75

 Cys Ile Val Leu Val Lys Gln Phe Arg Pro Pro Met Gly Gly Tyr
                  80                  85                  90

 Cys Ile Glu Phe Pro Ala Gly Leu Ile Asp Asp Gly Glu Thr Pro
                  95                 100                 105

 Glu Ala Ala Ala Leu Arg Glu Leu Glu Glu Glu Thr Gly Tyr Lys
                 110                 115                 120

 Gly Asp Ile Ala Glu Cys Ser Pro Ala Val Cys Met Asp Pro Gly
                 125                 130                 135

 Leu Ser Asn Cys Thr Ile His Ile Val Thr Val Thr Ile Asn Gly
                 140                 145                 150

 Asp Asp Ala Glu Asn Ala Arg Pro Lys Pro Lys Pro Gly Asp Gly
                 155                 160                 165

 Glu Phe Val Glu Val Ile Ser Leu Pro Lys Asn Asp Leu Leu Gln
                 170                 175                 180

 Arg Leu Asp Ala Leu Val Ala Glu Glu His Leu Thr Val Asp Ala
                 185                 190                 195

 Arg Val Tyr Ser Tyr Ala Leu Ala Leu Lys His Ala Asn Ala Lys
                 200                 205                 210

 Pro Phe Glu Val Pro Phe Leu Lys Phe
                 215

<210> 3835
<211> 10215
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4908, 5098, 9196
<223> Unknown base

<400> 3835
 gcggccgctg cttctttcac actttagttg ggagctgcgc gccgcgctca 50

 gttactggag agctggccgc gcgccgccgc ctcccgcacg cttgcacgcg 100

 ggcccggctt cggggttttg ggttcttact ccaagcggcg gggaggaggg 150

 ggagccccgg acacactgtg gggaggagga ggaagaagag gaggagggag 200

 gaagaaaaaa gacgaggagg acaggggcgg ggggcgggag gcttgccacc 250

 ttcagccccc ccgcgaacgc ccaaggtgca cacatcttga ccaactcagc 300

 agcaaggtgg attttctttg tgtttaaaga aaaaaaatgt ccctgtgtct 350

 gtagagatga tttgcagttc agcccggctg aagctgaccg aatgagacta 400

 tgggctgtgc ctccgccaag catgttgcca ctgttcaaaa tgaagaggaa 450

 gcccagaaag ggaaaaacta ccagaacgga gatgtgtttg gcgatgagta 500

 taggatcaaa ccagtggaag aggtcaaata catgaaaaat ggggcagaag 550

 aagagcagaa aatagcagcc aggaaccaag aaaacttgga aaaaagtgcc 600

 agctcaaatg taagacttaa aactaataaa gaggttccgg gattagttca 650

 tcaacccaga gcaaacatgc acatctctga aagccaacaa gaattcttca 700

 gaatgctgga tgaaaaaatt gaaaagggtc gggattactg ttcggaagaa 750

 gaggatatca catagcacca attttaccac tcaaaccagg agctactact 800

 gtgtaaatag gttacacccc agttgaaatc tttgcaaagg tcggttctat 850

 tcagcgaaca gcactatagc aaaagaagat cgttccatat tgtacgcccc 900

 attaaattac agtgtttctt aatgaacttg caaaggaata ttgctaaaaa 950

 caaacaaaaa aaactgttat cgaactttct ttgttgctgc tagttaaaac 1000

 ttgttgcaac ttttcacttc tcttgtgtcc aggtatgcag caaaattctg 1050

 caatttcacc ttaaagatac tgttggtttt acagatgctc tccaacctat 1100

 tttctataag atgaggtagt ggtgaactca gataacaaac ttcccttcta 1150

 aactggttct gcttctaaga caagcatctc ctgccctctc tccttcctcc 1200

 ccatctctcg cacgcagtct agagatggac tgagccttgc ttctcactgg 1250

 cagtgttgag ctttggagat gggatggttg ctatgccaag ccttgtttct 1300

 ctgctcagaa gaagtagaga agctattatc aattaaaagc atgctgtgat 1350

 gtgactcctg gaagtgacgt aggagtgagt ggcaggttgt ttgatttaat 1400

 aggtatctta atcaagaatt aagcttgcaa cattggcttt gctcagatgc 1450

 agatggaagt gtgatcacaa tcattttgaa tccctcttcc tcactttttt 1500

 ttctaagaaa ataaacattt tactgttttt atggatcctt gtcttctccc 1550

 attcatccag ctcagtgttt taagatgatc ctgggtgcag aagttgagcc 1600

 ctcctttgca ttgacactga taattagcct atagggctcc ctacccttcc 1650

 attaagaatc taccaagcat tagcaaggct gaaagtggtc taagaggtga 1700

 ggggacatcc tatgactttt taggaaggcc tgaaaccacc ttgttacctt 1750

 tcattttgtt agcaaataaa ccatcctatt ttgtaactct cccccttcaa 1800

 aatgctacat gagccttgcc acttcctttt tctcttactt ccagcacact 1850

 agacatagca aaagtgtttg cctactcaaa aacataatac ttttatgctg 1900

 atgatggtat ttggagatgt gaaagccaaa agcccctggc agtggtgggg 1950

 aatgttgact gagtgttcag cagagtttat ttttccatac tatatgaaga 2000

 gaatgatctc ttctcaaaga cagaagtgat atttttaaca aatattgtca 2050

 caagtaaata gcaatcaaaa ggagaaaata acttttgtat ttttttaatg 2100

 tgtttgatag ctttgacgag ggttctcttt gttactttca ggggagggca 2150

 tcctattaaa tgccacgcca gcagtccggg tctgggtttg tcccacaaaa 2200

 tcacaggagc actgtatgtt cctctctttt ggagttgtga ctttgaaggg 2250

 cctcaatatt agccacactg ccgcctgcag aaggtggaga gttaagatgt 2300

 tctatgtcaa tttgctcttg ccgaaaagat gagcctcgat tttaaaatct 2350

 atccacatcc aactgatggc accattgatg tgcaaataat gagattccct 2400

 atctcctttt agacctggga cggcaaaagg gaagggaagg aaacttagca 2450

 gagtgctatt gactatagat tcacatatta gcaacaaaat cccgtaattc 2500

 ttttggccaa cagcagctat tttggggagc agctgtggct gttacataaa 2550

 tagagatgca gccaaaattt taggcctttt atcctgcttc tagcagaaaa 2600

 atgcagggag agtcaagtag tctagggttt caggttgcct cccctcatat 2650

 ggtttttggc caagtgacta aaacagtttt ccacaactgt aaacaaactg 2700

 gtaagcccca cctcaaactt gttcactggg gactttgctt accgttctgt 2750

 gggtgacctt ttccgggatt tcttgttctt atcaagcaag aattaagcac 2800

 atgctaaacg tcttccattt gacttctcta ctcggtgtct cagacagtgt 2850

 cttcccagaa aaccaccacc ctctacccaa agatgaaaca tgctcatgtc 2900

 atttttctca tggtcacatt taacagtttt gacatgttat acttgcgcat 2950

 agatccaagc gtttcttggg aacctgactt ttgagtgttt aataaagccg 3000

 gaagtggtgt tgccctgaac cagcagattt tcacctgggt tctggctccg 3050

 gtgtttaaca ctggatacat ctttgatgtg cgaaagtgag ttcatcttca 3100

 gacacatttg gtacatccag aaatagatcc aagaaatggg gtggttgagt 3150

 gggtccgcac gaaatgcttg attatgtcag caacacccaa cactgtctgt 3200

 tttccatttg ttggttttaa tcataaaatt gtcaagtgat tcgtgttgta 3250

 ctttattttt gtgccttctg aacggatcta aaacaaawgt attttgcctt 3300

 ttttacccca cgtgtatctg aacattaagc agattggctc agacaccatg 3350

 aaaaggatac tccaatgtac gtgctggtgc actctgctag ttgttatctc 3400

 tgtagggctc aagaagctgg aaggaggaag ggagggtaag tggcctggtg 3450

 agtggaggta gaaaaatgat gagaaatgaa ctgagagcat taagcagaga 3500

 gggttgatag gctggccgtg tccggggtga aattggaaat ccagctgcct 3550

 agtggccagt gggtggggca agactgtcaa cgagatttac agctggctta 3600

 cacatgcctt atgtcctctg agttgtagag ttgtaaaagt tcagcagtgt 3650

 gtgcacagct ttcttttggt tggcagagat tcaggatcat ggagtactgc 3700

 tctcataatt gaagacgtgt ttgttattgg cagagaacct taaaaaaggc 3750

 ctttacctca gcgatgcttc ctagccccag gcttgcagag aacacagagt 3800

 ggtgttgtgg tctatttagg gacaaagaag gtataaagtc cagagatgag 3850

 aaaactgggt cagccctcag aaactgcagc agccacgcac acagaagcct 3900

 gctggaagac aggtctctct ccgtccacag tgcccatcat ctgagcctgg 3950

 gctgggatga ctcaacttag caaagacgga cccaggagga gtgctggttc 4000

 ttcagtcttt gtactggccc catcctctcc tcactgtaat gtgaggaagc 4050

 acctctgtgt cagggctcac ctgggcatcc aaagcggcca cgcccacaat 4100

 ccgacagccc ccaggagcag gtccagggat gatgcagccc ccttcttggt 4150

 cccatgtgat gtcatcctgc tttgttatct tcttataact ttatcctgct 4200

 ataactttat cctcttccca gcctcatccc tgtttttctg ttagggcaag 4250

 actcttccat aagcctgcta aaaaacagag atgatacctc ttacaaactt 4300

 tacctcatag cctgtgaagc aggttggcat gtggattaca agtcctgctt 4350

 tgacactggg caagaattta agattgttct atctctacta gtcatagaaa 4400

 agaaacattg ttaaacatgt tgagttttaa aggaagaaat attttcaaat 4450

 tcttaatcca agaaaatact gagttggaat cttagacttc gggactctga 4500

 cacgttcttt atgaaaggca aaataattgg tatctaaagt tctctccttc 4550

 ctgcctcccc taaagaaaaa ggatattaga ttgcacacta taattttaca 4600

 taagatctgc cttccacact tccctgctgg aaggcattct cagagcttta 4650

 tgtcttcgta cctctcagag attggacttt ttcttgttta aaaccccaac 4700

 caaaaaaaat aataaggcat gattggtggg gagggaatgt gtatttaggg 4750

 gcataataaa aaggtggctc gaagcaggaa ctttggcctc atggtgtcat 4800

 gggtggatgc ctggactcca gtgtgcctgt gaggggctgg gttaggcagt 4850

 cggctgtcac actcacatgt gcctgcaata aaccttttgg aatttcatga 4900

 acgaggtnct atgaattgcc ttttgccaat gaatggatgt atttttccaa 4950

 ggggggaata gtatccttga ctttggcagt cacctttttg tatgtctcta 5000

 garaggggtc aaaaaaacta tggtaaagat gaggcttatg agtgaatacc 5050

 tctgggacaa accttaggac tcacaagcta tgccatgttt ttcagganac 5100

 tctgtaccta tctggaatcc aatcctggga gaagaggaaa aaggagctaa 5150

 tatttgtcct ttatactcac tctgtgccag atactgtgsc aggcatttat 5200

 aattgtttgt gtcaccccat gatatccgtt aaattaatct attacccccg 5250

 tgttctaaat aatagatctt aagtgtggaa tgcatctatc caacataaat 5300

 gcccatgttg aaagaaggaa agatgtcatt caagtatttt tcaaattctt 5350

 tttattatga ctatgccctt cgcaacactg tgaaaacaac ccctgggggc 5400

 atctgccttc cagaatctct ctctggcttc tcaccagctt ggtttcctca 5450

 tggggagtgt tttatttggc ctcccctatc tgakctgcac acacaccagg 5500

 gggaggccac tggctaacag taggacttca gtgccctgag gaaaaggctt 5550

 tgggaattta ggcacacgtt tctctccttg gaatccttct agcatctgga 5600

 aaaggaacct ggtatttctg cagttagata ccagatgcac cagaacaggc 5650

 ttcgagtgct gtgattcttc ctggttccca agtcttgttg ttcatcacaa 5700

 actgtatctt tttaaggtta aaagtcttga ccttcatggg gtctgggaca 5750

 atccgatctc caagcatgga ggaaaggcaa tgcctggacc actgacttgc 5800

 attgaaatcc tttcttgtgg gctagggttt gatgtctctt tttcatcttt 5850

 ggactgggga tctgcatctt ccaggtccat ttaagcactg aaactagatg 5900

 caaatctctt tcgagacctt acatgtttta gatagtcatg taatgacttg 5950

 gatagacatt taaataactt gttccaaggt cggaagaccc aagaactcct 6000

 cagagttcct cttcttgctt cttgaatcac atcctctaaa gatgactcat 6050

 gtctccatag caattgttaa aggtgctgcc tagacgggac ccgctcccac 6100

 ctttacttac tttgctcgaa ggaaccaaaa caatgtcctt gtgtaaaggg 6150

 gctgtcatat ccagttttcc tttgaaatct ggcccccaag atcctgcttc 6200

 tttctaacct ggcagctgtc atgtcccttc aagatgatgt gggaaatggc 6250

 ccttacaact tgggaaccac agaaattgct gtatttcggg aagattcacc 6300

 tctaaactga aggcttcatt ctgatagtgt ctgccctctc taccctgatt 6350

 tcgcccttct ttgcttccat ttttagccca aggctttgaa tttgattgag 6400

 taagacttag aggcagtata aagaacacca taaacttagg cagaggtccc 6450

 ttagggtctc tagagttgaa aataattcta cagccttagg gggacctctt 6500

 ggcattgact ctaaagggag agaatagccc ctgtgtcctg gcatttcagt 6550

 ctagaccttc aaggactgtt ctctcttgac aggcaagcaa gcaaagaaag 6600

 ttttgcaata gatttcaagc cagtttttcc attcaaacca agatgcaaat 6650

 tcataaaatt actcttttcc tggaatagat ccaggcagct gccttattag 6700

 aactttagat tcggatctat tttcttaaca cacatacaca tacacgcgca 6750

 tacatacata tacagagaga tacgtggaga aaggaaattt actctatcat 6800

 tgcaatactt caagaaagag ctgtattttg cctttctgta atctccaaga 6850

 tagtgtctag gaaagtaata gtataactat agggataccg aaacaggaaa 6900

 aaccagccat cactcttgag aaagtttgag ttcgactcac atgggagaat 6950

 cgaggtctgc tactcgtctt gctttgtgcc ccatctgtgc ctggatgccc 7000

 tactacayct gcttgactcg tctgggctgc tagccggggt gttgtggctg 7050

 acatcctttc ctggccttac acacataata gacacatccc taacggcgtg 7100

 tgcctggtcc agccacatac agccaccaca tgtgtcacac actgtccccc 7150

 tcatccatgt ggacttgact ggcatttcag cagctccact gggatgctct 7200

 aaccccagtg tgtggagttg gggtcccttc atctaggttg acccaggtat 7250

 agcattttta gcattgcctt tccagtcttg atgattcatt cattgaactc 7300

 atttatttct ggagcccctg gtacactcca ggcactgcgc taattgccag 7350

 caaagcacaa ctgaactaaa tccaccttca aggaacctag ccataacgag 7400

 ggaggcagca tggaagtacc ctacagggga aagtcctgag tgctgtggga 7450

 gcatctcacc gtggcagcca gcccagtttt ggcaatcagg ggcttcctga 7500

 aagaggtgac atcaaagccc ggatgtgtca gaggactgag ggagagtgtt 7550

 actaaaggac tttcaggctg agaggatagc acaggactca gcccaaagga 7600

 gggccagtgt ggactgtcca gggccagcct gcagtacaga ggctggagct 7650

 tggacttgta gagggagaga gaagagcaag ggacgtggac ggggcagtga 7700

 gccaggctag ccacagaggg ttcccggggc tttgctgggg attcagggag 7750

 cataaataag agctttaggt ggtgctgtgt cctctgcagc ccactgctga 7800

 ggtcctccag acagrtaagg tgtggtcaca atcagggccg gggtttccct 7850

 gctcactgcg gcagtgcagg ggtgcttgct gagatgaytc atcccagggt 7900

 gtcctctgtc ccttacccag ccccaactcc tcttcctctg ccaaaagcta 7950

 tttgaattca aggactttaa cctgggccgg atctggtttg gagacaaagg 8000

 ggacagctct gggtcagcat gaccttcttt agagccacta aggcgaaaaa 8050

 taccgtttgg gaccaggctg gcctagaccc agggatgaga atgcacccta 8100

 aaataaatat acgggaagca gcagagggct tccctgtcta gtgtgtgatc 8150

 ctaactaaag gcagctctct tgggcagcct tcccctggat taggtcacat 8200

 acacctggtg gccaagcctc tgctgggtcc caaatacaca cccgagtcct 8250

 gccaaagaaa ggagattttt aaaaagcaca gacaaattgt atgcaagtgg 8300

 aaaataccca taggcctaga cagctgtgga gggaagacct cgtgggtacc 8350

 tggaggctgc cagagctggg agctctgcag gtatgagtca gggaaggctc 8400

 agagacaagc agaatctctc tatggagaca acttgcagtg ccttttaggt 8450

 tttccaaata acctcggagt tcagagcatt gggttttttt ctcccctccc 8500

 cacccccaga aaaataatta gaaaaatgtt taggagaaag gaaaagaatt 8550

 agatgcatca gaataccagc tataagccaa cactgtttcc agaaactcaa 8600

 gaaaaagctc aaacagaaga cagttcccct gagaggctgg aggcgttggt 8650

 gctgaaggca attttcctag ctaaggggca ctgggccttg ctgcaccttg 8700

 gggctgacct tttttgcaaa acacccaccc ctgccctcct ggcatactca 8750

 acagcaacgc cagctttctg gacccttgga aagatgttag ctcaaacacc 8800

 cactttttcc agatcttcct cttgctcttc actgaggaat ttgtaattct 8850

 gaggctagcg atgccgactc ggatattccg cagcccaggt gtttagatta 8900

 gaatttgtcc agcggtaatc ctgatgctgg aaaccaacaa acatttggcc 8950

 tcatattcac ccatttaaaa actagagccc ctggcaggtc cccttagggc 9000

 catgtgttca tggaatataa gccaagtttg ccytagcgct kgttcatgga 9050

 atataagcca agtttacctc tccccatttt ctgccctggc ccacttccca 9100

 ctcacctcca cctcattgcc aggaagggat caaaatgcct ccatgccagt 9150

 tgttaaatgg ctacatattt gcccttccca agggtatttg catttntatt 9200

 taggaacatg gccttatatt caaggaaaat ctagcatcaa gattacgagg 9250

 catcacctct caatcaggtc tgggaggtat cttggggcat tgctcttctg 9300

 aacacctgca gaggcttcct caggtgagtg tgggagcccg gaagtggcct 9350

 ccctaaccac tctgcctgca catgaattct ccaaagcagt gggcccccat 9400

 ctgtttcaat tacacatgcc tgtcagcaaa aacttcgtga gatgcactct 9450

 ctctgtgtgt ttattaattt atttaaagca tatatccctt tacttttgta 9500

 ctactatatt aggcacatta taaaaagtat acagcataga aactttaaat 9550

 gaataagaca caaaatatta taaacagagg ttctggcatt ttctctctga 9600

 actcctgagg gggaccttgg gcacctcctg gtatgtgcac accccacttt 9650

 gaacaccctt gctttagtgc aaatcagcac gcctaaatrg catcccaaac 9700

 ccactgtgcg acatttggcc tgcagaatag gaaagtccta ggscagaatc 9750

 cccaggaact tcaaatctgg gagatgagga aagaaaactc actcacaaac 9800

 aacataaatg taaataattc aaaaccctaa aggagagctg tccctagaca 9850

 gtagtggcta caggtgctaa gcaaaagtca ggtacactgg acagagccat 9900

 gcgattgatt gttcatcttc cctctctggg tctccagaaa aggacactgg 9950

 caatatcccc agctctctcc tgattggaat tctttgaacc ctcgaagtgc 10000

 tccagcagta ctacccccca cgtagcagtg ggcccatgtc gcttgaatat 10050

 tatttttgat ttgaccacca agatgtaatg atgattctat tccattttga 10100

 aaagggtctg agaaagtgta caggtctaat tatatataca tatttataca 10150

 tgtgtatttt tgtttattgt tacattttga cattggactt tctattaaat 10200

 aatttttaag agttg 10215

<210> 3836
<211> 121
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4908, 5098, 9196
<223> Unknown amino acid

<400> 3836
 Met Gly Cys Ala Ser Ala Lys His Val Ala Thr Val Gln Asn Glu
   1               5                  10                  15

 Glu Glu Ala Gln Lys Gly Lys Asn Tyr Gln Asn Gly Asp Val Phe
                  20                  25                  30

 Gly Asp Glu Tyr Arg Ile Lys Pro Val Glu Glu Val Lys Tyr Met
                  35                  40                  45

 Lys Asn Gly Ala Glu Glu Glu Gln Lys Ile Ala Ala Arg Asn Gln
                  50                  55                  60

 Glu Asn Leu Glu Lys Ser Ala Ser Ser Asn Val Arg Leu Lys Thr
                  65                  70                  75

 Asn Lys Glu Val Pro Gly Leu Val His Gln Pro Arg Ala Asn Met
                  80                  85                  90

 His Ile Ser Glu Ser Gln Gln Glu Phe Phe Arg Met Leu Asp Glu
                  95                 100                 105

 Lys Ile Glu Lys Gly Arg Asp Tyr Cys Ser Glu Glu Glu Asp Ile
                 110                 115                 120

 Thr


<210> 3837
<211> 2645
<212> DNA
<213> Homo sapien

<400> 3837
 gcggccgcca tggcggagaa ttggaagaac tgcttcgagg aggagctcat 50

 ctgccctatc tgcctgcacg ttttcgtgga gccagtgcag ctgccgtgca 100

 aacacaactt ctgccggggc tgcatcggcg aggcgtgggc caaggacagc 150

 ggcctcgtac gctgcccaga gtgcaaccag gcctacaacc agaagccggg 200

 cctggagaag aacctgaagc tcaccaacat cgtggagaag ttcaatgccc 250

 tgcacgtgga gaagccgccg gcggcgctgc actgcgtgtt ctgccgccgc 300

 ggccccccgc tgcccgcgca gaaggtctgc ctgcgctgcg aggcgccctg 350

 ctgccagtcc cacgtgcaga cgcacctgca gcagccctcc accgcccgcg 400

 ggcacctcct ggtggaggcg gacgacgtgc gggcctggag ctgcccgcag 450

 cacaacgcct accgcctcta ccactgcgag gccgagcagg tggccgtgtg 500

 ccagtactgc tgctactaca gcggcgcgcg tcagggacac tcggtgtgcg 550

 acgtggagat ccgaaggaat gaaatccgga agatgctcat gaagcagcag 600

 gaccggctgg aggagcgaga gcaggacatt gaggaccagc tgtacaaact 650

 cgagtcagac aagcgcctgg tggaggagaa agtgaaccaa ctgaaggagg 700

 aagttcggct gcagtacgag aagctgcacc agctgctgga cgaggacctg 750

 cggcagacag tggaggtcct agacaaggcc caggccaagt tctgcagcga 800

 gaacgcagcg caggcgctgc acctcgggga gcgcatgcag gaggccaaga 850

 agctgctggg ctccctgcag ctgctctttg ataagacgga ggatgtcagc 900

 ttcatgaaga acaccaagtc tgtgaaaatc ctgatggaca ggacccagac 950

 ctgcacgagc agcagccttt cccccactaa gatcggccac ctgaactcca 1000

 agctcttcct gaacgaagtg gccaagaagg agaagcagct gcggaaaatg 1050

 ctagaaggcc ccttcagcac gccggtgccc ttcctgcaga gtgtccccct 1100

 gtacccttgc ggcgtgagca gctctggggc ggaaaagcgc aagcactcaa 1150

 cggccttccc agaggccagt ttcctagaga cgtcgtcggg ccctgtgggc 1200

 ggccagtacg gggcggcggg cacagccagc ggtgagggcc agtctgggca 1250

 gcccctgggg ccctgcagct ccacgcagca cttggtggcc ctgccgggcg 1300

 gcgcccaacc agtgcactca agccccgtgt tccccccatc gcagtatccc 1350

 aatggctccg ccgcccagca gcccatgctc ccccagtatg gcggccgcaa 1400

 gattctcgtc tgttctgtgg acaactgtta ctgttcttcc gtggccaacc 1450

 atggcggcca ccagccctac ccccgctccg gccactttcc ctggacagtg 1500

 ccctcgcagg agtactcaca cccgctcccg cccacaccct ccgtccccca 1550

 gtcccttccc agcctggcgg tcagagactg gcttgacgcc tcccagcagc 1600

 ccggccacca ggatttctac agggtgtatg ggcagccgtc caccaaacac 1650

 tacgtgacga gctaacgcca cgcaggcggc ggggcgctgg ggaatcttcc 1700

 tccccagccc ccgggctcgg gagttatgca tccagagacc tgcccttcta 1750

 ccttcctcgc ctcccctctt cctcattcca ttgccccagg tcttttcctt 1800

 ttggattttg ttttggtttt ggctttgttt ttgatttttt tttattatga 1850

 atctcctgga cgcagaggtg acagtgggag ctggcctggg ccaggacggc 1900

 aggtggccct ggagatggga aagtgtctgt gtcgaggcgc tgagctctct 1950

 ctctgtttct ccttttttcc tctactcctt ccccttcaca cccccgtggc 2000

 tggaaggaac ctcggcttcc ctgaaagctt gggggtccca cccttcttac 2050

 cccacccggg aggaacgccc agggccccgg gcttgtttct cctcttgttt 2100

 tccttttggg cagtttgatc actgatcgag taaggaatga cctttagatt 2150

 gtgcgacttt tgtttttgtt tttttaaatt tttttaaacc aagaatgatt 2200

 tctcctgctt ccttctcctc accatcttcc cagacggagt tcaaaggcca 2250

 cttctcaagc agcttttggc accttcagcc tcagagtgga atcttttaaa 2300

 gacaggaccc ctatgtccag gaaaggggaa aaggaacttt gccaatgata 2350

 gtgaccacag caaaagcaaa taataataat attaataata ataaagagaa 2400

 ataaaataat aaaataaaaa acaatagcac agcccttgtt gaggtcagca 2450

 gggaggaggg gctgcccgga gttgggtcct tgcctggatt ttgacacagc 2500

 aacttcctgt agtgagcact ttgtatgaat cgtggacttc ctgttctcaa 2550

 ggcgcaggta tttattctgt atctgtctag cgcacacacc aaaatccaac 2600

 cttctaataa acatgatggc gcagtcccaa aaaaaaaaaa aaaaa 2645

<210> 3838
<211> 551
<212> PRT
<213> Homo sapien

<400> 3838
 Met Ala Glu Asn Trp Lys Asn Cys Phe Glu Glu Glu Leu Ile Cys
   1               5                  10                  15

 Pro Ile Cys Leu His Val Phe Val Glu Pro Val Gln Leu Pro Cys
                  20                  25                  30

 Lys His Asn Phe Cys Arg Gly Cys Ile Gly Glu Ala Trp Ala Lys
                  35                  40                  45

 Asp Ser Gly Leu Val Arg Cys Pro Glu Cys Asn Gln Ala Tyr Asn
                  50                  55                  60

 Gln Lys Pro Gly Leu Glu Lys Asn Leu Lys Leu Thr Asn Ile Val
                  65                  70                  75

 Glu Lys Phe Asn Ala Leu His Val Glu Lys Pro Pro Ala Ala Leu
                  80                  85                  90

 His Cys Val Phe Cys Arg Arg Gly Pro Pro Leu Pro Ala Gln Lys
                  95                 100                 105

 Val Cys Leu Arg Cys Glu Ala Pro Cys Cys Gln Ser His Val Gln
                 110                 115                 120

 Thr His Leu Gln Gln Pro Ser Thr Ala Arg Gly His Leu Leu Val
                 125                 130                 135

 Glu Ala Asp Asp Val Arg Ala Trp Ser Cys Pro Gln His Asn Ala
                 140                 145                 150

 Tyr Arg Leu Tyr His Cys Glu Ala Glu Gln Val Ala Val Cys Gln
                 155                 160                 165

 Tyr Cys Cys Tyr Tyr Ser Gly Ala Arg Gln Gly His Ser Val Cys
                 170                 175                 180

 Asp Val Glu Ile Arg Arg Asn Glu Ile Arg Lys Met Leu Met Lys
                 185                 190                 195

 Gln Gln Asp Arg Leu Glu Glu Arg Glu Gln Asp Ile Glu Asp Gln
                 200                 205                 210

 Leu Tyr Lys Leu Glu Ser Asp Lys Arg Leu Val Glu Glu Lys Val
                 215                 220                 225

 Asn Gln Leu Lys Glu Glu Val Arg Leu Gln Tyr Glu Lys Leu His
                 230                 235                 240

 Gln Leu Leu Asp Glu Asp Leu Arg Gln Thr Val Glu Val Leu Asp
                 245                 250                 255

 Lys Ala Gln Ala Lys Phe Cys Ser Glu Asn Ala Ala Gln Ala Leu
                 260                 265                 270

 His Leu Gly Glu Arg Met Gln Glu Ala Lys Lys Leu Leu Gly Ser
                 275                 280                 285

 Leu Gln Leu Leu Phe Asp Lys Thr Glu Asp Val Ser Phe Met Lys
                 290                 295                 300

 Asn Thr Lys Ser Val Lys Ile Leu Met Asp Arg Thr Gln Thr Cys
                 305                 310                 315

 Thr Ser Ser Ser Leu Ser Pro Thr Lys Ile Gly His Leu Asn Ser
                 320                 325                 330

 Lys Leu Phe Leu Asn Glu Val Ala Lys Lys Glu Lys Gln Leu Arg
                 335                 340                 345

 Lys Met Leu Glu Gly Pro Phe Ser Thr Pro Val Pro Phe Leu Gln
                 350                 355                 360

 Ser Val Pro Leu Tyr Pro Cys Gly Val Ser Ser Ser Gly Ala Glu
                 365                 370                 375

 Lys Arg Lys His Ser Thr Ala Phe Pro Glu Ala Ser Phe Leu Glu
                 380                 385                 390

 Thr Ser Ser Gly Pro Val Gly Gly Gln Tyr Gly Ala Ala Gly Thr
                 395                 400                 405

 Ala Ser Gly Glu Gly Gln Ser Gly Gln Pro Leu Gly Pro Cys Ser
                 410                 415                 420

 Ser Thr Gln His Leu Val Ala Leu Pro Gly Gly Ala Gln Pro Val
                 425                 430                 435

 His Ser Ser Pro Val Phe Pro Pro Ser Gln Tyr Pro Asn Gly Ser
                 440                 445                 450

 Ala Ala Gln Gln Pro Met Leu Pro Gln Tyr Gly Gly Arg Lys Ile
                 455                 460                 465

 Leu Val Cys Ser Val Asp Asn Cys Tyr Cys Ser Ser Val Ala Asn
                 470                 475                 480

 His Gly Gly His Gln Pro Tyr Pro Arg Ser Gly His Phe Pro Trp
                 485                 490                 495

 Thr Val Pro Ser Gln Glu Tyr Ser His Pro Leu Pro Pro Thr Pro
                 500                 505                 510

 Ser Val Pro Gln Ser Leu Pro Ser Leu Ala Val Arg Asp Trp Leu
                 515                 520                 525

 Asp Ala Ser Gln Gln Pro Gly His Gln Asp Phe Tyr Arg Val Tyr
                 530                 535                 540

 Gly Gln Pro Ser Thr Lys His Tyr Val Thr Ser
                 545                 550

<210> 3839
<211> 1286
<212> DNA
<213> Homo sapien

<400> 3839
 ggcacgaggc tgccgcgctg tccgcgttat ctcctcccgg tgagaacgaa 50

 ccgcagtgtc caccggcgag gagccagccc tgtcccggtc agagaaagac 100

 gacgaggata cctgggagcg ggcggcggcc gggctgggcc gcgccggtgc 150

 gggctggcga ctctgctcct ccgcttgctg ctgtctctgg gaactgggtg 200

 ccagcgctga ggggcttcca gcggacaggg acccccttcc ccggctcccc 250

 tgcccaccct gccggggagg gcggaagatg ccggtgaaga agaagagaaa 300

 atcccctggg gtggcagcag cagtagcgga agacggaggc ctcaaaaagt 350

 gtaaaatctc cagctattgc agatcccaac cccctgctag actaataagt 400

 ggagaggaac atttttcaag caagaagtgc ctggcttggt tttatgaata 450

 tgcaggtcct gatgaagttg tagggccaga aggaatggaa aaattttgtg 500

 aagacattgg tgttgaacct gaaaatatta ttatgttagt tttagcgtgg 550

 aaattggagg ctgaaagcat gggatttttt accaaggaag aatggttaaa 600

 gggaatgact tcattacagt gtgactgcac agaaaagtta caaaacaaat 650

 ttgacttttt gcgctcacag ttgaatgata tttcgtcatt taagaatatc 700

 tacagatatg cctttgattt tgcaagggat aaagatcaga gaagccttga 750

 tattgatact gctaaatcta tgttagctct tctgcttggg aggacatggc 800

 cactgttttc agtattttac cagtacctgg agcaatcaaa gtatcgtgtt 850

 atgaacaaag atcaatggta caatgtatta gaattcagca gaacagtcca 900

 tgctgatctt agtaactatg atgaagatgg tgcttggcct gttcttcttg 950

 atgaatttgt tgagtggcaa aaagtccgtc agacatcata gcaagaacta 1000

 tgtgaagaaa atgcaaacct ttcaattccc acgtgtatac aagctaatgt 1050

 gatgaggggg aaaaaaatcc aacgggtgca ttttcattca tatgaaagac 1100

 ttctcatagt actttttttt ccttttttta aaggaggttt ttcttgttac 1150

 atgtgatggg cattgagcca cacctcttct tagactgaat attgaagttt 1200

 ttgttttgag ttatgtttat aacatttatt tcagaacaat aaagattcag 1250

 atttgtgaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 1286

<210> 3840
<211> 237
<212> PRT
<213> Homo sapien

<400> 3840
 Met Pro Val Lys Lys Lys Arg Lys Ser Pro Gly Val Ala Ala Ala
   1               5                  10                  15

 Val Ala Glu Asp Gly Gly Leu Lys Lys Cys Lys Ile Ser Ser Tyr
                  20                  25                  30

 Cys Arg Ser Gln Pro Pro Ala Arg Leu Ile Ser Gly Glu Glu His
                  35                  40                  45

 Phe Ser Ser Lys Lys Cys Leu Ala Trp Phe Tyr Glu Tyr Ala Gly
                  50                  55                  60

 Pro Asp Glu Val Val Gly Pro Glu Gly Met Glu Lys Phe Cys Glu
                  65                  70                  75

 Asp Ile Gly Val Glu Pro Glu Asn Ile Ile Met Leu Val Leu Ala
                  80                  85                  90

 Trp Lys Leu Glu Ala Glu Ser Met Gly Phe Phe Thr Lys Glu Glu
                  95                 100                 105

 Trp Leu Lys Gly Met Thr Ser Leu Gln Cys Asp Cys Thr Glu Lys
                 110                 115                 120

 Leu Gln Asn Lys Phe Asp Phe Leu Arg Ser Gln Leu Asn Asp Ile
                 125                 130                 135

 Ser Ser Phe Lys Asn Ile Tyr Arg Tyr Ala Phe Asp Phe Ala Arg
                 140                 145                 150

 Asp Lys Asp Gln Arg Ser Leu Asp Ile Asp Thr Ala Lys Ser Met
                 155                 160                 165

 Leu Ala Leu Leu Leu Gly Arg Thr Trp Pro Leu Phe Ser Val Phe
                 170                 175                 180

 Tyr Gln Tyr Leu Glu Gln Ser Lys Tyr Arg Val Met Asn Lys Asp
                 185                 190                 195

 Gln Trp Tyr Asn Val Leu Glu Phe Ser Arg Thr Val His Ala Asp
                 200                 205                 210

 Leu Ser Asn Tyr Asp Glu Asp Gly Ala Trp Pro Val Leu Leu Asp
                 215                 220                 225

 Glu Phe Val Glu Trp Gln Lys Val Arg Gln Thr Ser
                 230                 235

<210> 3841
<211> 903
<212> DNA
<213> Homo sapien

<400> 3841
 tagtcacgct cggtaccagg cgcagatcat ggcaggcagc cggctggaaa 50

 ccgtagggag catcttctct cggactcggg acctggttcg ggccggggtg 100

 ctgaaggaga agcccctgtg gtttgacgta tatgacgcct ttcccccgct 150

 gagggagccc gtcttccaaa ggcctcgagt gcgatatggc aaagccaaag 200

 ctcccatcca agacatctgg taccacgagg atcggattag agcgaagttt 250

 tattcagtgt atgggtctgg tcaaagagct tttgatctat tcaatccaaa 300

 cttcaagtct acctgtcaac ggtttgtgga gaagtacact gagctacaga 350

 aacttggaga aacagatgaa gagaagttat ttgtggaaac agggaaggct 400

 ttattggcag aaggtgtcat tttaagacga gtaggcgaag caaggactca 450

 acacggaggt agtcacgttt cccggaaatc cgaacacttg agtgtcagac 500

 cacagactgc gttggaagaa aacgagactc agaaagaagt tccacaggac 550

 cagcatttgg aggcacctgc agaccagtcg aaaggtctct tgcctccctg 600

 aaggacctgt atactgtgta tgctggcatt cacactctac tcactggctg 650

 aatgttgagc tatttttaaa cagttgaact gtgtaaatgt ttcttgatct 700

 ctaaggtatt atgtttgcct tctcttagtt atttctgggt tgtcacaaag 750

 ctcagtatca tggtttgaca gaagcagtta tgtgaacttt tatgttagga 800

 cattactaaa taaagaattc cctagctgct tataaagtaa atttactttg 850

 aattgtaaat aacatgaaga aacctttata aagattgttc aaatgggact 900

 caa 903

<210> 3842
<211> 190
<212> PRT
<213> Homo sapien

<400> 3842
 Met Ala Gly Ser Arg Leu Glu Thr Val Gly Ser Ile Phe Ser Arg
   1               5                  10                  15

 Thr Arg Asp Leu Val Arg Ala Gly Val Leu Lys Glu Lys Pro Leu
                  20                  25                  30

 Trp Phe Asp Val Tyr Asp Ala Phe Pro Pro Leu Arg Glu Pro Val
                  35                  40                  45

 Phe Gln Arg Pro Arg Val Arg Tyr Gly Lys Ala Lys Ala Pro Ile
                  50                  55                  60

 Gln Asp Ile Trp Tyr His Glu Asp Arg Ile Arg Ala Lys Phe Tyr
                  65                  70                  75

 Ser Val Tyr Gly Ser Gly Gln Arg Ala Phe Asp Leu Phe Asn Pro
                  80                  85                  90

 Asn Phe Lys Ser Thr Cys Gln Arg Phe Val Glu Lys Tyr Thr Glu
                  95                 100                 105

 Leu Gln Lys Leu Gly Glu Thr Asp Glu Glu Lys Leu Phe Val Glu
                 110                 115                 120

 Thr Gly Lys Ala Leu Leu Ala Glu Gly Val Ile Leu Arg Arg Val
                 125                 130                 135

 Gly Glu Ala Arg Thr Gln His Gly Gly Ser His Val Ser Arg Lys
                 140                 145                 150

 Ser Glu His Leu Ser Val Arg Pro Gln Thr Ala Leu Glu Glu Asn
                 155                 160                 165

 Glu Thr Gln Lys Glu Val Pro Gln Asp Gln His Leu Glu Ala Pro
                 170                 175                 180

 Ala Asp Gln Ser Lys Gly Leu Leu Pro Pro
                 185                 190

<210> 3843
<211> 6496
<212> DNA
<213> Homo sapien

<400> 3843
 gtgggcgtgg tgtgctatag agtgtactgc tgctgctgct tggccaacgt 50

 ttcactgcct ggcatcgggg gcaccattcc tgagtccaaa cctttcttct 100

 acgtgaacgt ggctgacatc gagagcctgg aggtagaggt gtcctatgtg 150

 gcctgcacca cagagaagat attcgaggag aagcgggagc tgtatgacgt 200

 ctacgtggat aaccagaatg tgaagacaca ccacgaccac ctgcagccgc 250

 tgctgaagat caacagtgct gacagggaga agtaccgccg gctcaacgag 300

 cagaggcaga tgctgttgta ctcccaggaa gtagaagaag actacaaccc 350

 ttgtgaagag gacctcttcg tgctgttttt cctagaacaa aacaaccgga 400

 tatttcagac tttgttggag gtgtctgcca gtcaagacaa aactctgaca 450

 gcagagcatg cccggggcat gggcctagac ccccaaggag accggagctt 500

 tctcctggac ctgctggagg cctatggcat tgatgtcatg ctggttatcg 550

 acaacccctg ttgcccgtag gaggagccaa caggactggg agccgcttca 600

 cgtgggatgt cagcagcccg gagttcaccc cagggcccca gagggcctca 650

 ttttttatta agttgacaca aaggaatatt gtttatactt tccaacaaac 700

 ataatttttg caatttcctt tctgcccttt tccctagaga taaggtgaga 750

 tcaccttggt tttgtgtcct gccatgttag gatattggaa tctgccactt 800

 tctcccagag ctgctggtcc tctgggcttg gtcatgggag ttgtatcact 850

 aggagtaggc tgagctctgg aaacattggg atggactgtt cagaaagtct 900

 gtgtggtctt tgtcccttga tgtatttgag aataagacaa ccacctgtcc 950

 cctgtggcct tagatgttca tctgcctaaa ggcagaaact agaccagatg 1000

 atcttttaag gtttttagta gttctaggag tctatagtct tgggatcaaa 1050

 tcccttttct tgttcattag ggcaacttta tgtcttctct gtttacttga 1100

 gtagggacca caaagaggga aaaaaggatg tttctgacac caaatatgag 1150

 cttatcttat ggtcagaatg aaagaggttg cttatcagtg agctgaaaac 1200

 taaaattata gaatgaagcc tggaaacctt cctcaaagta acttgatggt 1250

 ggccatgcaa tgtaatgttc ctctttgtct gaaccttcct cttcttggga 1300

 tgaattggtg aattgctaag ggccaatgct ggccttggag cttgcaagca 1350

 aattaatttt ccagtttagt ctcttaaggg ttcaataatg ctcttggagt 1400

 aagttgggta tttttaaagg ctgaagtttg gactaccgga ggatagagca 1450

 attgaagttc gagcaggatg gagaagccac tctaagtctc ttcatctgga 1500

 cacgaattct ctggaggcat tagcagcagc acctctgggt caacacagat 1550

 ttactggatt ccaaaatcta gcaaggatct gagctggtta actcagaggg 1600

 tggagcatga tgctaacaag acggtttatc attttggacc cctcacaaac 1650

 acacttctct ttagcagagg tgacattcct taggctaaat aattggatcc 1700

 agggacataa cagatttgtt gagagaaaat gtggcagtgc cttcacccgg 1750

 gacagtggtc aggaagccct gagcatccct gatggattta tccatcctct 1800

 tctgaagtgc tctgctctag gctgggtcct gttgccacct gcctgttctc 1850

 tggttggctt ttgcaggagg gcagcttacg tgtttgtcaa ccagttagaa 1900

 agccagttcc tgtgggtcga gtttaggcct ttttggccat agttgagaat 1950

 tttgacttgg gatactgggt tgttggtgac aaataatgtc ttccttttcc 2000

 cccttcccgc ctggctcggt tatgggaata gccgtcagtg catccatgtc 2050

 tgtgaccaac acccagccag actaatgtac acagcaggga gaaataacat 2100

 tcaaatggtg gttcacacat ctcatctcaa gataagattc ttagggttca 2150

 ctgctttatt caaaagtgtt ttcactgtag ctccttcata tggaatatca 2200

 aaactgaaga aattcacatg tggaaatgca aatagacatt gattaatcaa 2250

 ggtagcatct ttatgtaaat atataaataa gtttgggcat tgaaatgtaa 2300

 actgtacagc taatagactt ttctcctctg caatgtgggt tgctgtcatt 2350

 tcagtaatgt gtatgtttac aaaagaaaaa aaaatctgtg tttcgaggtt 2400

 gaagcctcac cttttattct cctttacatg caaccctctc ttcttgcctc 2450

 tcaagggttg aggggtcctt tctgtcaagt aatggttatt tttcgtggta 2500

 tcctgaggtt cagggtgttt taagctgggg gtaggtggtt agaggcagga 2550

 gtagaagtga aaggaaaggt ctgattctcc tagaggacac aagaagacct 2600

 cctttttctg gaattaggga atctgccgga aggagctgtt tgaggcattt 2650

 ctgctctgag ccttctatat gcaaacactg cagttttaac tgcaagctca 2700

 gaagtgctgg tgtaaacata gcagggtgag aatgaagttc ctgttttttc 2750

 ctttgaatgg tgagtcaggg cttctgggtt cccttaactt tgtgcttgtc 2800

 tcggtagctt tctgtctcac atctccacgt gtccaccctc ctgctcatgc 2850

 agagggccag ggtatgggtg gccccagagg agaacgtgcc agtgaggcag 2900

 tgccatgttt caggtcatag gggccttggg ctcagctgac cccaatgcag 2950

 aacttctccc tttaagagag attccaataa attggtcctt ccctaccttg 3000

 ccagcttctt cataggacca gaaatcttgt gcagagcctc tgcttggctg 3050

 aacagcgtgt gctttatctc ttcagttacc tttgccactg ttgagcatcc 3100

 tcagagtatg tcttgcctgg gctatgaagt ggagcctgtg gcttcggaaa 3150

 tcacctttcg aagccttgct ctatgccaga ttctgctccc caacatgaca 3200

 gattaacagg cacaacctag gatcctttgc taccagttct ctactaggga 3250

 attccacagt ggcagcagaa gctaggagcc atgtggacct gcttttctgc 3300

 cagtcttgaa atattttctg agaaaccatc tgcttttgtt cagaagaaag 3350

 tgctgaacat cgttcacaga cttctaggtc tgtaagctct ttaggggcgg 3400

 gcattatgat gaccaccggc ctcctggagg agggttggat acctgtggtg 3450

 tgacaccttc tgccaccatc tcctgccggg cctcagccct cgcctgcctg 3500

 agcaggccta gttctcctgt gaagctgtca gcctgatctc atgccacact 3550

 gtgaaatgaa ctatgtgcca gtttggaaat gattgctgac ctgagatgct 3600

 ggctgggctg ccctgttgtt cctgaataag tcagaagaag ttccaggtgg 3650

 gagtggaatt caggtttggg gctcgttggt atccatgcaa aatatgacaa 3700

 aggcctgttc aagagggcat tttcaattct gtaggctcag cagatgatac 3750

 tgcccagcct ttgggaaaat gtccagttgg cccctggctt aggactctcc 3800

 acaaggagtt tgaaatggta gggcttatcc cctaccagac taaaagtatg 3850

 gcccaaatta tgtgtttaga atttgcttgg cctttaaaca cgaaccattc 3900

 cctatgcctg gtagagacca ttccagtatc agtgtcccac ctgggacctg 3950

 tacagtcctc agtaaattat gattgcaatg aattagaagg cttttgcctt 4000

 ccatatccat catccattat agcatctgtg cttccacctg gttaggggga 4050

 gggaagctga aatcattgat gtatcaatag aagtaattta gcttaggaac 4100

 ttgcatctat aacttacctt gttttgttcc actttaaagt caagacaaga 4150

 aagttaagat agcacacagg tgcacatgct tccagatgcc acatgtgaac 4200

 atttgttgat catgtgacta ccgatgacac tttagctaga agataaatta 4250

 aatcttagct aaatcattgt ttttccttct ggtggctatg aggatgaatt 4300

 tgctctcagt cttgatgcac tgaaagccct tcaaacacag taaaagatga 4350

 aatcactcat ctttaaactg aggccttcag ggaagctttt gtaaaggaca 4400

 gtaatgaatt aggctttcag ttttaggaca tcaaccctcc gagaaaaggc 4450

 agaaacccga gggaccattt atttcccttc gaaactgtat agcccaggga 4500

 atggattgag atgctttctc cagaccctgt ataggtcaac cttgcagagg 4550

 taaaggagga ggggcaggtg gatgaataaa ataggataat gctcagcttg 4600

 gcagtggact tgccttagtg tgatgacagg tctaacatgg gcaagacaat 4650

 tagaatgggg accaatatgc caggcatggg cttttatctc cctagtagat 4700

 cccaagctag taggcttgga ttctgccaaa tggccagccc tcctgtcttc 4750

 tccccgtacc ttgtagttag accgaggtga gaatcctgct gaccccagtc 4800

 ccatcccctc tcatttcagg aaaacccttt tgtgattcag gtagggggag 4850

 aggaggagtt aagggctccg tttactccca agtcatggat ttttaatatt 4900

 ccatttttat cactaatata cctctcttcc tagaagctac tggagtattg 4950

 agtgttgtgg gaaaaggcta actgtgaatt aagttaatgt ttttcttata 5000

 agaaatggaa gtttattttt ttattgatat tactatgtga tgaactgagt 5050

 atgcatatac tgaaatggaa ggaaatttta aaactattat tctagaagaa 5100

 atgggcagtt ttgtaatttg gtggtggctg agaccccata gaagttttac 5150

 tatgtaaata atttggagag tgaataagga gattgtgcta tgaaatcctg 5200

 acagcgctct ttaggaggca gacttgacag tcctaggaag gttgacataa 5250

 aaataccaac cttcagtaaa gctctagtac aaaaaagggt aaatgtcatc 5300

 attcttattt ttaggcctct ttcttgagag aggtgggagt gggaggtagt 5350

 gttataactg gcactttaat ttgtttttgg aactagaatt taggggcagt 5400

 tggatgaaat tgcaaattta gaaggggaat aagaattttc tagtgctata 5450

 taaagaaatg atgatggaga caaaagcctt gctttcctct ttttagaatt 5500

 tattttcgat ttttagcata ctgtggggct tttagagcta atatgatcta 5550

 aattcagaaa atttaatttt catagtaggc caggtgtgaa ttacttatgt 5600

 ttgctataga atgcttattt agactaacaa taaatttact ttgctttcta 5650

 aggccagtca gcgaatgtgg ggatgaggca ggatgtttta aatgagccag 5700

 agatgatcca caaagtgaac agtcgacaca gaggtctttg agttggatgg 5750

 ttgcaaatat attgacatta gagtgaaaac tccttccttt gggtaaacta 5800

 aagaaagata aagtatacta aaaaatttta agatggtgtt atacaaaaaa 5850

 aagtttgggt ctaacgtgtc cacaaagact gtcaagtgaa gaatggtgga 5900

 gattcttggt gtttgagcag ccaacctgga tgagtgactt cagggacaga 5950

 gcagaggaaa gcaaaatgaa tttcctttat ttacccaaaa cttgttgact 6000

 gaatttttgt ataggtccgg gaaaataagc ctaaacaaat agttgtagcc 6050

 ttagaaaaac tgttttccca tttctttctg agttagaatc agcatagcct 6100

 ccctgtcgcc ttaaatgtaa aaatcctatt ttgattaata ccccagccta 6150

 agagttatag caatacgaga gactgaatct atttttgttt cgggtcttta 6200

 cctcatagta tgaaattagt aagacactgc atagattttg ccctgaatac 6250

 tggtgtgccc aggtatgccg tgctctctct ctgtttccag tggtggtaat 6300

 tttaaggcct aaagaaagct ggggttaatc ctgaagctaa aagtaaatgt 6350

 ttcttgaatt gattttgttc tgtggtacaa ataacatcta tgaatatcat 6400

 atctgtatat atctgaacca agttgtgtgc agagaggttg atataactat 6450

 atttacagaa aatgattttt acaattaaag ttcacatttt aacatg 6496

<210> 3844
<211> 189
<212> PRT
<213> Homo sapien

<400> 3844
 Val Gly Val Val Cys Tyr Arg Val Tyr Cys Cys Cys Cys Leu Ala
   1               5                  10                  15

 Asn Val Ser Leu Pro Gly Ile Gly Gly Thr Ile Pro Glu Ser Lys
                  20                  25                  30

 Pro Phe Phe Tyr Val Asn Val Ala Asp Ile Glu Ser Leu Glu Val
                  35                  40                  45

 Glu Val Ser Tyr Val Ala Cys Thr Thr Glu Lys Ile Phe Glu Glu
                  50                  55                  60

 Lys Arg Glu Leu Tyr Asp Val Tyr Val Asp Asn Gln Asn Val Lys
                  65                  70                  75

 Thr His His Asp His Leu Gln Pro Leu Leu Lys Ile Asn Ser Ala
                  80                  85                  90

 Asp Arg Glu Lys Tyr Arg Arg Leu Asn Glu Gln Arg Gln Met Leu
                  95                 100                 105

 Leu Tyr Ser Gln Glu Val Glu Glu Asp Tyr Asn Pro Cys Glu Glu
                 110                 115                 120

 Asp Leu Phe Val Leu Phe Phe Leu Glu Gln Asn Asn Arg Ile Phe
                 125                 130                 135

 Gln Thr Leu Leu Glu Val Ser Ala Ser Gln Asp Lys Thr Leu Thr
                 140                 145                 150

 Ala Glu His Ala Arg Gly Met Gly Leu Asp Pro Gln Gly Asp Arg
                 155                 160                 165

 Ser Phe Leu Leu Asp Leu Leu Glu Ala Tyr Gly Ile Asp Val Met
                 170                 175                 180

 Leu Val Ile Asp Asn Pro Cys Cys Pro
                 185

<210> 3845
<211> 1837
<212> DNA
<213> Homo sapien

<400> 3845
 ggcacgaggc ccgggtcgag catgtagcgg ctgctggcgg cggggctccc 50

 ggggcgggcc gggcgggccg cgggagccgc acgcggcgat atggaagagg 100

 agggcaagaa gggcaagaag cctggaattg tctcgccatt taaacgagta 150

 ttcctaaaag gtgaaaagag tagagataag aaagcccatg agaaggtgac 200

 agagaggcgc cctctgcaca ctgtggtgtt gtcattgcct gagcgcgtcg 250

 agccagacag actgctgagc gactatattg agaaggaggt aaagtattta 300

 ggtcagttaa cgtccatacc aggatacctg aatccctcca gtaggactga 350

 aatcctgcat ttcatagaca atgcaaagag agcccaccag cttccgggac 400

 acttgactca ggagcacgat gctgtgctca gcctgtctgc gtacaacgtc 450

 aagctggcct ggagggacgg ggaggatatc atcctcaggg tgcccatcca 500

 tgacatcgcc gccgtctcct atgttcggga tgacgctgca cacctggtgg 550

 tcctgaagac agcccaggac ccagggatct cccccagcca gagtctgtgt 600

 gcggaaagtt ccagaggcct cagtgcaggc tccctgtcgg agagtgcagt 650

 tgggcccgtg gaggcatgct gcctggtcat cctggctgca gagagcaagg 700

 tcgctgcgga ggagctttgc tgtctgctag gccaggtctt ccaggttgtt 750

 tacacggagt ccaccatcga ctttctggac agagcgatat ttgatggggc 800

 ctctaccccg acccaccacc tgtccctgca cagcgatgac tcttctacaa 850

 aagtggacat taaggagacc tacgaggtgg aagccagcac tttctgcttc 900

 cctgaatctg tggatgtggg tggtgcatca ccccacagca agaccatcag 950

 tgagagcgag ctgagcgcca gcgccactga gctgctgcag gactacatgc 1000

 tgacgctgcg caccaagctg tcatcacagg agatccagca gtttgcagca 1050

 ctgctgcacg agtaccgcaa tggggcctct atccacgagt tctgcatcaa 1100

 cctgcggcag ctctacgggg acagccgcaa gttcctgctg cttggtctga 1150

 ggcccttcat ccctgagaag gacagccagc acttcgagaa cttcctggag 1200

 accattggcg tgaaggatgg ccgcggcatc atcactgaca gctttggcag 1250

 gcaccggcgg gccctgagca ccacatccag ttccaccacc aatgggaaca 1300

 gggccacggg cagctctgat gaccggtcgg caccctcaga gggggatgag 1350

 tgggaccgca tgatctcgga catcagcagc gacattgagg cgctgggctg 1400

 cagcatggac caggactcag catgatggac agtggatggg ggggcaccca 1450

 caccttccgc gcagtcgtca taggccttcc cagaaggagc tgcccagacc 1500

 tgcgtgtcag cccttggtgg tggccaggga gaggcgcccg gtgcagatgg 1550

 ccccgggcgg cccaggtcct ctactgtgaa ggagcaggga gctgccgagg 1600

 gacacgagcc tcagtgcggg gtggaaggct ctttgccttg tccaccaggg 1650

 ctcagccaag ccctgcagtg tgtccccgct cggggagggc ccggccgagc 1700

 gggcagggag agccagtcct gtcggctggg cccttggacg gctgtcagtt 1750

 ttgcacatga tgttcctatt gtaactctca gagaccttaa aaagaagttt 1800

 actgcaatgt gaataattta aaaaaaaaaa aaaaaaa 1837

<210> 3846
<211> 444
<212> PRT
<213> Homo sapien

<400> 3846
 Met Glu Glu Glu Gly Lys Lys Gly Lys Lys Pro Gly Ile Val Ser
   1               5                  10                  15

 Pro Phe Lys Arg Val Phe Leu Lys Gly Glu Lys Ser Arg Asp Lys
                  20                  25                  30

 Lys Ala His Glu Lys Val Thr Glu Arg Arg Pro Leu His Thr Val
                  35                  40                  45

 Val Leu Ser Leu Pro Glu Arg Val Glu Pro Asp Arg Leu Leu Ser
                  50                  55                  60

 Asp Tyr Ile Glu Lys Glu Val Lys Tyr Leu Gly Gln Leu Thr Ser
                  65                  70                  75

 Ile Pro Gly Tyr Leu Asn Pro Ser Ser Arg Thr Glu Ile Leu His
                  80                  85                  90

 Phe Ile Asp Asn Ala Lys Arg Ala His Gln Leu Pro Gly His Leu
                  95                 100                 105

 Thr Gln Glu His Asp Ala Val Leu Ser Leu Ser Ala Tyr Asn Val
                 110                 115                 120

 Lys Leu Ala Trp Arg Asp Gly Glu Asp Ile Ile Leu Arg Val Pro
                 125                 130                 135

 Ile His Asp Ile Ala Ala Val Ser Tyr Val Arg Asp Asp Ala Ala
                 140                 145                 150

 His Leu Val Val Leu Lys Thr Ala Gln Asp Pro Gly Ile Ser Pro
                 155                 160                 165

 Ser Gln Ser Leu Cys Ala Glu Ser Ser Arg Gly Leu Ser Ala Gly
                 170                 175                 180

 Ser Leu Ser Glu Ser Ala Val Gly Pro Val Glu Ala Cys Cys Leu
                 185                 190                 195

 Val Ile Leu Ala Ala Glu Ser Lys Val Ala Ala Glu Glu Leu Cys
                 200                 205                 210

 Cys Leu Leu Gly Gln Val Phe Gln Val Val Tyr Thr Glu Ser Thr
                 215                 220                 225

 Ile Asp Phe Leu Asp Arg Ala Ile Phe Asp Gly Ala Ser Thr Pro
                 230                 235                 240

 Thr His His Leu Ser Leu His Ser Asp Asp Ser Ser Thr Lys Val
                 245                 250                 255

 Asp Ile Lys Glu Thr Tyr Glu Val Glu Ala Ser Thr Phe Cys Phe
                 260                 265                 270

 Pro Glu Ser Val Asp Val Gly Gly Ala Ser Pro His Ser Lys Thr
                 275                 280                 285

 Ile Ser Glu Ser Glu Leu Ser Ala Ser Ala Thr Glu Leu Leu Gln
                 290                 295                 300

 Asp Tyr Met Leu Thr Leu Arg Thr Lys Leu Ser Ser Gln Glu Ile
                 305                 310                 315

 Gln Gln Phe Ala Ala Leu Leu His Glu Tyr Arg Asn Gly Ala Ser
                 320                 325                 330

 Ile His Glu Phe Cys Ile Asn Leu Arg Gln Leu Tyr Gly Asp Ser
                 335                 340                 345

 Arg Lys Phe Leu Leu Leu Gly Leu Arg Pro Phe Ile Pro Glu Lys
                 350                 355                 360

 Asp Ser Gln His Phe Glu Asn Phe Leu Glu Thr Ile Gly Val Lys
                 365                 370                 375

 Asp Gly Arg Gly Ile Ile Thr Asp Ser Phe Gly Arg His Arg Arg
                 380                 385                 390

 Ala Leu Ser Thr Thr Ser Ser Ser Thr Thr Asn Gly Asn Arg Ala
                 395                 400                 405

 Thr Gly Ser Ser Asp Asp Arg Ser Ala Pro Ser Glu Gly Asp Glu
                 410                 415                 420

 Trp Asp Arg Met Ile Ser Asp Ile Ser Ser Asp Ile Glu Ala Leu
                 425                 430                 435

 Gly Cys Ser Met Asp Gln Asp Ser Ala
                 440

<210> 3847
<211> 4346
<212> DNA
<213> Homo sapien

<400> 3847
 gcgtgggcgc cagaaagcgg aacctcccgg gccagtcgcg cggtggtcac 50

 cctcttggga gctggggagg aggctgcgga ggctggcccg gctccttcgg 100

 gcgtcgcttc ccggaccggg tgcgcggggt cccccggaac gtgtgttcca 150

 ggtcctcccg cgccagtgtt cgcagtcccc gcctggtcgc ggcggcgcct 200

 cgggcgcggg tgcaggcgcg cggcgcgcag gcggggggcg ctgtggtctt 250

 ggcgcgggga ccgagccgct cggccagacc cgcctctttt ccctccccgc 300

 cagcccgccc gcctgcccgc cccccacgcg tcgtgtcgcc gggaagccgg 350

 gcggagacag agcgcttggg atccacggcg ctcggaccgc tgtcctccaa 400

 cagcgcaggg cagagcggct ggcgccgccg gagcgcggag ccacgaccct 450

 ccctggccgc ctttgtctac tggccgtgcg gcccggaacc gccactctcc 500

 agggccgggg acgcgcccgc agctgtcggt gacagctcct ccctaccgca 550

 accctccggg gcggaggggc ggtcgggccg ggccctgcta gcccgcgacc 600

 gcaagcccgc gctcgcggat cgatgccccc gcagcagggg gaccccgcgt 650

 tccccgaccg ctgcgaggcg cctccggtgc cgccgcgtcg ggagcgcggt 700

 ggacgcgggg gacgcgggcc tggggagccg gggggccggg ggcgtgcggg 750

 gggtgccgag gggcgcggcg tcaagtgcgt gctggtcggc gacggcgcgg 800

 tgggcaagac gagcctggtg gtgagctaca ccaccaacgg ctaccccacc 850

 gagtacatcc ctactgcctt cgacaacttc tccgcggtgg tgtctgtgga 900

 tgggcggccc gtgagactcc aactctgtga cactgccgga caggatgaat 950

 ttgacaagct gaggcctctc tgctacacca acacagacat cttcctgctc 1000

 tgcttcagtg tcgtgagccc ctcatccttc cagaacgtca gtgagaaatg 1050

 ggtgccggag attcgatgcc actgtcccaa agcccccatc atcctagttg 1100

 gaacgcagtc ggatctcaga gaagatgtca aagtcctcat tgagttggac 1150

 aaatgcaaag aaaagccagt gcctgaagag gcggctaagc tgtgcgccga 1200

 ggaaatcaaa gccgcctcct acatcgagtg ttcagccttg actcaaaaaa 1250

 acctcaaaga ggtctttgat gcagccatcg tcgctggcat tcaatactcg 1300

 gacactcagc aacagccaaa gaagtctaaa agcaggactc cagataaaat 1350

 gaaaaacctc tccaagtcct ggtggaagaa gtactgctgt ttcgtatgat 1400

 gctggcaaga cacccagaaa ggctattttc agatgaaatc gatattagaa 1450

 gctatattag ctgaaacaac tccttttact gcgtagaacc tatatcgaga 1500

 gtgtgtgtat atgtattata ggaggagctc tcaattttat gtattctttc 1550

 tgcctttaat tttcttgttt gtttgagctt agggatgaga tacttatgca 1600

 agatattttt gaagtaaatt aaacattttt cacatctctg gaaatttaga 1650

 gttctagacc tctggttaat ttatatctaa tatgaagaag acacctctaa 1700

 tctggatgtt aagaatgaag ttctgctaca ttataatgta cagaagagca 1750

 aaagggagga acactatggt taaccctctc ttgattaagg gctacttaat 1800

 gcacagtgca ttatgtacac aggtcaacca tggtaacaat agttcttagc 1850

 tttgaaactc catgcaaacc atgccttttt tttaaggagc aaaaatctga 1900

 gaaaaaaagt gagagacctc tgcctacaaa acctcaaacc agtcactttt 1950

 gtcaattgct aatacccagt tacttatgat ttaaaaacaa ccaacagaaa 2000

 acatcccact gactgtatgg cactctgtag tcaaaaaagg aaacttcctt 2050

 attgggactt ttctttctta gtccagttgt gttgacacat atgaacacag 2100

 acaaagtgct atgcggagga aagcaagtgt tggtcagtag tttcatgttt 2150

 tagggagtgg ttcctgtgga gatcagaaag tgacatttgc tttcggtact 2200

 gtaatacgtg caccaaactg cctcaatcct aggtaacgag ggcaacaggg 2250

 agcacctgtc tggattgttt ttaaacctcc atactcaagc tgtctcttcg 2300

 gcagggaggt gaatactctt gaaaggccaa cagcaagtgt ttgtgggaca 2350

 caacacagat aattttttct taagtcggcc aagatgtact tctctgtgtg 2400

 cacacccatg cacactcatg cacacagata cataggtctg tatggctgta 2450

 tttgctgttg attcagactt tcacaccatt aatggggaaa agcgtggcca 2500

 caaaaacaga tgctaggaag cttggcttcc tcttcttgtt gacccttttt 2550

 tgaaccaaca tcttttttat tatattcaga gtatgttttt aagtgtatct 2600

 taatatatac attttttagg acatcttaaa tctaaacaaa aaataaaatg 2650

 aacatctctt gaaacctgtt aaaacaacca gttaaagcca cagatggctt 2700

 tcagggcagt agcagcagag gccagtggac tctgaggact cctgaggggc 2750

 ggggcgtgta gccagccagg tgcatgccgg gaccatggcc cccatacttg 2800

 gctgcttcct gtgacagtga aatacatcct tcaaggtggc agctgttagg 2850

 gctgaatctt ctggagaaaa aggtgccatc tcaggagaat agcttttact 2900

 ctggtaggaa tgcttccgag acaccacaag gcagcctgaa cactcagttg 2950

 cagggtcggg cttgcggtgg gtgacccaga gccaccaaag tcacatccac 3000

 aactaatgag ggaaatctgt aaagccagtt agatagaaga attttatttt 3050

 tctgtgggtt ttgtgttgtc ttttttatgt taaaaagaaa tccagtttgt 3100

 gtttttctat agaaaaagta aaagatcagg ttatacttta ggttaggggt 3150

 tctatttatt cctgttagta aataaaatta acaaatttct ttgtttaaca 3200

 aaagattaat ctttaaacca ctaaaataca tagactgatt gattattcaa 3250

 cacattggaa ttgatgtcgg tcatagtttc ctgaagcatt tagttacaac 3300

 ctgaaggaat aaaatgattt gtggaaatgc ttaaaataga cctaactgaa 3350

 tacagtctca tcttgccgcg cctggcttac ctatctgtgg aaagctaggc 3400

 ttcccaggct gggctctgcc tgtctggtgc ctggaggtgt gggagggaag 3450

 atgagttatt taactggtaa gcgatttgaa acactatttt tatattaaag 3500

 taaatggcat ggagtatagt gcaaattcat ttttaagata gaacacaaaa 3550

 cttgaaagaa gttttatgcg tgtgacagtg tatggggctg cagttggtct 3600

 ccctggaggg gacttccaca cctcctgcct ttaggcatgg gtggaaagtg 3650

 ctcagtgaag tacacctgtg tggcccagtt ctgaaagctt tatacagttg 3700

 aattttaagt ggggttgata acaccttgga ctgttagtgt taaaaatcta 3750

 gtgggttgac ctttaaatgc aacagttttt aaaatatatt gctgcatttt 3800

 atagaatagt aaaggtacga ttatacttga gattttcctc catttttatt 3850

 tcttcgtgaa catagagttt ggggccgaaa atgtttttaa agtatgtgtt 3900

 tgagttaaat ataaagttgg ttcacttcaa agctaaaaaa ttgttaaact 3950

 tgcagcttgg tattgcagag aagattttat aagaattttg ctttagagaa 4000

 tgccactttg gctgaactac aagtgtaggc caccattata atttataaat 4050

 acagcatact tcaaaactgt ttgttatctc ttgttaccat gtatgtataa 4100

 atggaccttt tataaccttg ttctctgctt gacagactca agagaaacta 4150

 cccaggtatt acacaagcca aaatgggagc aaggccttct ctccagacta 4200

 tcgtaacctg gtgccttacc aagttgtgct tttctgtttt caagtgtaaa 4250

 tgatgttgag cagaatgttg tacttgaaaa tgctataagt gagatggtat 4300

 gaaataaatt ctgacttatg aataaaaaaa aaaaaaaaaa aaaaaa 4346

<210> 3848
<211> 258
<212> PRT
<213> Homo sapien

<400> 3848
 Met Pro Pro Gln Gln Gly Asp Pro Ala Phe Pro Asp Arg Cys Glu
   1               5                  10                  15

 Ala Pro Pro Val Pro Pro Arg Arg Glu Arg Gly Gly Arg Gly Gly
                  20                  25                  30

 Arg Gly Pro Gly Glu Pro Gly Gly Arg Gly Arg Ala Gly Gly Ala
                  35                  40                  45

 Glu Gly Arg Gly Val Lys Cys Val Leu Val Gly Asp Gly Ala Val
                  50                  55                  60

 Gly Lys Thr Ser Leu Val Val Ser Tyr Thr Thr Asn Gly Tyr Pro
                  65                  70                  75

 Thr Glu Tyr Ile Pro Thr Ala Phe Asp Asn Phe Ser Ala Val Val
                  80                  85                  90

 Ser Val Asp Gly Arg Pro Val Arg Leu Gln Leu Cys Asp Thr Ala
                  95                 100                 105

 Gly Gln Asp Glu Phe Asp Lys Leu Arg Pro Leu Cys Tyr Thr Asn
                 110                 115                 120

 Thr Asp Ile Phe Leu Leu Cys Phe Ser Val Val Ser Pro Ser Ser
                 125                 130                 135

 Phe Gln Asn Val Ser Glu Lys Trp Val Pro Glu Ile Arg Cys His
                 140                 145                 150

 Cys Pro Lys Ala Pro Ile Ile Leu Val Gly Thr Gln Ser Asp Leu
                 155                 160                 165

 Arg Glu Asp Val Lys Val Leu Ile Glu Leu Asp Lys Cys Lys Glu
                 170                 175                 180

 Lys Pro Val Pro Glu Glu Ala Ala Lys Leu Cys Ala Glu Glu Ile
                 185                 190                 195

 Lys Ala Ala Ser Tyr Ile Glu Cys Ser Ala Leu Thr Gln Lys Asn
                 200                 205                 210

 Leu Lys Glu Val Phe Asp Ala Ala Ile Val Ala Gly Ile Gln Tyr
                 215                 220                 225

 Ser Asp Thr Gln Gln Gln Pro Lys Lys Ser Lys Ser Arg Thr Pro
                 230                 235                 240

 Asp Lys Met Lys Asn Leu Ser Lys Ser Trp Trp Lys Lys Tyr Cys
                 245                 250                 255

 Cys Phe Val


<210> 3849
<211> 4113
<212> DNA
<213> Homo sapien

<400> 3849
 ggcacgaggc tgcggcttct ggctgcgcgg cctgcgcgcg cctcccgggc 50

 ggattccagc cccgagcggg acagcgcggc ggggagcgac gagatttctc 100

 tctgatcaaa cggacagttc aggactcaga atctaaggat gaatgttcac 150

 cgtggcagtg acagtgacag gttattgcgg caggaggcca gctgcttagt 200

 ggatgatact ttagctgtag cccaagaaaa agaagcaaac agcctggctt 250

 catctggtcc tcataatctt acttatcctc taggtcccag gaatgaaggt 300

 gctttactcc atgaactgtc taatgacggt gctcataagc agtttgatca 350

 ctacctcgaa gagctcatct tgcccatcat ggtgggctgt gccaagaaag 400

 gagaacgaga gtgccacatt gttgtgctga cggatgagga ttctgtggac 450

 tgggatgaag accaccctcc accaatgggg gaggaatatt cccaaattct 500

 ttatagctcc aagctctaca gattcttcaa atatattgag aatagggatg 550

 ttgcaaaaac agtgttaaag gaacggggcc taaaaaacat tcgcattgga 600

 attgaaggtt accctacctg taaagaaaaa attaagagaa ggcctggcgg 650

 ccggtctgaa gtcatctata attatgtaca acgccccttc atccagatgt 700

 catgggaaaa ggaagaaggg aagagtcgcc atgtggattt ccagtgtgtt 750

 cgaagcaaat ccctcacgaa tctggtagct gctggagatg atgtcttgga 800

 ggaccaggag atattaatgc atcacccacc ccaagtggat gaacttgacc 850

 ggctaaatgc cccactttct cagatggctt ctaacgactt tcaggattag 900

 ggccagctgt gggtctactc cttgttggag cccatctcac ctgggatgcc 950

 tgcagccagc cctccctcgt gatttgtctc accttgagta ggagacatgc 1000

 ttctccccta accttttcct ttctgccata attaacatat gtccttttca 1050

 gtaagtccat gcctctggca ggggatgaag aagtactcac tggtaattag 1100

 ctaccatctt tgcagcagcc ctggtaactt gaaaaatttg ggtctggtgc 1150

 tgttcattga gtctttgtgt aactgcaaaa gcaggaaagg aagtcaagac 1200

 tcctgttgcc tcgtgcttag caaagcagtc cttatccttt atactctgtt 1250

 cttgggtttt gtttttgtct tgttttatac caggcaaatt gcttagtagc 1300

 aaagggacca aactgaaaag gtgacaatct ctaacttcta aaagcagaca 1350

 ccaatcggat gctcattaga ggttaatgaa gatgccattc ttggtggcct 1400

 ctgcacccaa attgcatctg gaaagaacta gggtctcatt cagaatgtcc 1450

 aaaaggaaat tcttaagagc ttaaattcag atttgtgtct cattaatgca 1500

 gtgaacaatt caaaaccaca cagattcctt ggcaggaagg ataatggaat 1550

 aacagtgttg atgagacctt tttagcttca aggtttcgga gtctaaacaa 1600

 atggatgatt catttggaat gaaactcaca atgcaagtag aaggacctct 1650

 ccaaatcagg ccagttgggt tatcctggct tggaatctgg tgtgaaacca 1700

 taggtcttaa cactctggag cagcacattg ctgtggatat gtccaggaga 1750

 ccttagatat ggcttaaagg ctttcaagat gaggacagaa attgcttaca 1800

 attgctcagt ttctcaacag aaagactcat aagagtgcca gcatggggta 1850

 catggagtga agctgggtgg gaagcatcat ctgcacagtc cctgtcctag 1900

 tgcaggactt ttctctgtat gttttcatac catgggattt ttggatatca 1950

 gtgtattttg gttcttgaaa tagcctaata gctgctcaca cattgggtag 2000

 gaatattata ccaatgtcat ccccaaagga agggtgagct gaatggaaat 2050

 taagcccagt cattttattt gatctattag ctctgttatc agtgcatgat 2100

 cacccagatc accctcctca gcccacacag tgctgaacca tcttccctcc 2150

 tgttctccat ggctattaat agtatagcta aatttagagt gcagagccag 2200

 atataagtat tttggaatta tctcccagtt tgtggtagaa gctgactgga 2250

 atacaggttg agtatctctt atccaaaatg ctagggacca gaaaggtttc 2300

 agattttttc agattttgga atacttaaca gttgagcacc ccaaatctga 2350

 aaggcttctg aacgtcatgt cagcactcaa aaaagtggat tttggagcac 2400

 ttcaaatttc ggatttttgg atttgggatg ctcatcctgt gtaggagagg 2450

 ctactcgatt ccatttaatg actgtcctag tcataatcat ccaaagataa 2500

 aagccaggta gatgttgaaa gctctttcca gggctgaaaa agtgttctta 2550

 cgttctctgc atgtgactag catcactgtg gaaattaatg ctctgttctt 2600

 cactagaatg tagtaagtgg ttaaactgag ctatccccca cctgatgact 2650

 attggcatcc atttgcaagg ccaatggcct ggattaaggg ttaggattat 2700

 ttgtagctag aaggtaattt tatttctgtg aaactaattg gctcatattt 2750

 gaggttaggt gtggccttga ccttaccagt acatttatac ccactaccag 2800

 ttgactagcc cagataattg ttaaatggtg cttcttttct gcttctcagt 2850

 agacttccat gccattacaa aggaaatttg aattacctag tgtttgtata 2900

 ttccatgata actatgtata acttctgtta cacagcttat gtattgttaa 2950

 catttaagtg taaaccatgc cacagctaac acttaaaaat gaaaactaat 3000

 tagttcttgc ttagggaaaa tgccaggtat gaagtatggc atatacttga 3050

 cactgtcctg tgtaaccctt tactttgctc aggctttcaa gattgagtct 3100

 tttttccccc aaattaggtt aacatgcatt tgaccccaac ctgtggggtt 3150

 tgagtaagct ggaaatctgt gacggtaggc tttctagtgt cacgaggtgg 3200

 tggtgactga aggaaaagct gggatcacag gttccttctg atggagagga 3250

 aggtttattt ctatgcccct cccaccaccc tccacctaga gctcacccaa 3300

 gcctgctcca gtcccagggg caggccattc tgcaaaagca ggacctcaca 3350

 gaaacaaggg ctgggttgag gtcaccccct tcagagttgg ttcctggcca 3400

 gatgggtaag aggcatttgt aattttaaaa atgtgaaact tgggtttggt 3450

 gttttcttct aagtgcctaa ataagcaagc caggctgttg atattttagc 3500

 cagagaaatc ggcaagccaa gattaacccg aatctgaagt ttagaatctt 3550

 gagtttgcat ctgcatcata tcatgctgtt ttgatgagga aacatttgcc 3600

 actgaggagt tggagggagg gcaagacgac agtgttaagt cagatcattt 3650

 aatggtttcc cctaagccct ggaaaaatat ttgaaagaat ggcagcaaaa 3700

 aggttaagaa agcaagccag atttactgca caatatgcag tacccagtac 3750

 tactttaaat cccaagagaa cagtgtgatg tctaatatat acaggtctat 3800

 gaaaatactg tggaataagc ccaggaaggt tagatgtgtt tgcaaataag 3850

 ttgcccaaag ggtccccctc taagtaaaac aaatattcag accacaggct 3900

 ttaatgtaaa ctgtcaaaaa gtgggatgtg gaggattttt gttaagtgtc 3950

 aatcgaagtt aaaaagcaag ggtttttggc caggcgtggt ggctcacgcc 4000

 tgtaatccca gcactttggg aggccgaggc cggcaaatca cctaaggtca 4050

 ggagttcgag accagcctgg ccaacatggt gaaaccccgt ctctactaaa 4100

 aaaaaaaaaa aaa 4113

<210> 3850
<211> 253
<212> PRT
<213> Homo sapien

<400> 3850
 Met Asn Val His Arg Gly Ser Asp Ser Asp Arg Leu Leu Arg Gln
   1               5                  10                  15

 Glu Ala Ser Cys Leu Val Asp Asp Thr Leu Ala Val Ala Gln Glu
                  20                  25                  30

 Lys Glu Ala Asn Ser Leu Ala Ser Ser Gly Pro His Asn Leu Thr
                  35                  40                  45

 Tyr Pro Leu Gly Pro Arg Asn Glu Gly Ala Leu Leu His Glu Leu
                  50                  55                  60

 Ser Asn Asp Gly Ala His Lys Gln Phe Asp His Tyr Leu Glu Glu
                  65                  70                  75

 Leu Ile Leu Pro Ile Met Val Gly Cys Ala Lys Lys Gly Glu Arg
                  80                  85                  90

 Glu Cys His Ile Val Val Leu Thr Asp Glu Asp Ser Val Asp Trp
                  95                 100                 105

 Asp Glu Asp His Pro Pro Pro Met Gly Glu Glu Tyr Ser Gln Ile
                 110                 115                 120

 Leu Tyr Ser Ser Lys Leu Tyr Arg Phe Phe Lys Tyr Ile Glu Asn
                 125                 130                 135

 Arg Asp Val Ala Lys Thr Val Leu Lys Glu Arg Gly Leu Lys Asn
                 140                 145                 150

 Ile Arg Ile Gly Ile Glu Gly Tyr Pro Thr Cys Lys Glu Lys Ile
                 155                 160                 165

 Lys Arg Arg Pro Gly Gly Arg Ser Glu Val Ile Tyr Asn Tyr Val
                 170                 175                 180

 Gln Arg Pro Phe Ile Gln Met Ser Trp Glu Lys Glu Glu Gly Lys
                 185                 190                 195

 Ser Arg His Val Asp Phe Gln Cys Val Arg Ser Lys Ser Leu Thr
                 200                 205                 210

 Asn Leu Val Ala Ala Gly Asp Asp Val Leu Glu Asp Gln Glu Ile
                 215                 220                 225

 Leu Met His His Pro Pro Gln Val Asp Glu Leu Asp Arg Leu Asn
                 230                 235                 240

 Ala Pro Leu Ser Gln Met Ala Ser Asn Asp Phe Gln Asp
                 245                 250

<210> 3851
<211> 936
<212> DNA
<213> Homo sapien

<400> 3851
 ctcggtgtaa acaagtccag gcgcctgcga acccgggccc gggggggacg 50

 gcgcccgcca ggagcgcccc ccactcccag gccagcccac cccggcggac 100

 cgggccccgc gcgcccaggc gaggcactgg gctccctctg ctccccgtgg 150

 gccgctcccc gcgtggggcc actgcccccg gcccccgcca tggtgcggat 200

 ttcaaagccc aagacgtttc aggcctactt ggatgattgt caccggaggt 250

 atagctgtgc ccactgccgc gctcacctgg ccaaccacga cgacctcatc 300

 tccaagtcct tccagggcag tcaggggcgt gcctacctct tcaactcagt 350

 ggtgaacgtg ggctgcgggc cagccgagga gcgggtgctg ctgaccggcc 400

 tccatgctgt cgccgacatc cactgcgaga actgcaagac cactttgggc 450

 tggaaatatg aacaggcctt tgagagcagc cagaagtaca aagaggggaa 500

 gtacatcatt gaactcaacc acatgatcaa agacaacggc tgggactgac 550

 ccccgctccc ccgacgcatg tggctccagc ccggcctggc cgccagggag 600

 cgccactggc ttcccgccac ccgaagggag ctttggaccc tcagagcccc 650

 tgcagaggac ggatctagct cctgtatata tattttattg catgcactgt 700

 gaccttgggg ggagaacaga agggggaaga cgcccccgca cctcctgcga 750

 tctggctggc ttggatttcg tttttaaccc gttcctgccc cacctgccct 800

 atagttatgg cctgtgtttt gctctcctgg tcccagtgca ccgtttgctt 850

 tgtgaactcc tcccaccagg ccctttttac cccacgggtg tctgtccccc 900

 tcgttttgta gcgtttgtac ataataaaac aatgga 936

<210> 3852
<211> 119
<212> PRT
<213> Homo sapien

<400> 3852
 Met Val Arg Ile Ser Lys Pro Lys Thr Phe Gln Ala Tyr Leu Asp
   1               5                  10                  15

 Asp Cys His Arg Arg Tyr Ser Cys Ala His Cys Arg Ala His Leu
                  20                  25                  30

 Ala Asn His Asp Asp Leu Ile Ser Lys Ser Phe Gln Gly Ser Gln
                  35                  40                  45

 Gly Arg Ala Tyr Leu Phe Asn Ser Val Val Asn Val Gly Cys Gly
                  50                  55                  60

 Pro Ala Glu Glu Arg Val Leu Leu Thr Gly Leu His Ala Val Ala
                  65                  70                  75

 Asp Ile His Cys Glu Asn Cys Lys Thr Thr Leu Gly Trp Lys Tyr
                  80                  85                  90

 Glu Gln Ala Phe Glu Ser Ser Gln Lys Tyr Lys Glu Gly Lys Tyr
                  95                 100                 105

 Ile Ile Glu Leu Asn His Met Ile Lys Asp Asn Gly Trp Asp
                 110                 115

<210> 3853
<211> 1343
<212> DNA
<213> Homo sapien

<400> 3853
 agaagggaag gtagacatca ggttctccct ggagactttt cgttttcatt 50

 tacgctgcgg aaactgacgt ttttgcctaa caccccatgt aatgtaaacg 100

 tataggcttg agtacgtgtc cggccgcatg tgtagtgaac cctaaagctt 150

 tcctaattgt agttagcatc gtccctaagc ggaacgattt tccgtgaaca 200

 tgatttgtac ttttctacga gccgtacagt atacggagaa gctgcacagg 250

 tcctcggcaa agcgattgct tttgccatac atcgtgctta acaaagcgta 300

 cttgaagact gagcccagtt tgagatgtgg gcttcaatat caaaagaaaa 350

 cgctgcgacc tagatgtatt cttggagtca cccagaaaac catctggacg 400

 cagggaccga gcccccgaaa agcaaaggag gatggcagca aacaagtgtc 450

 tgtgcacagg agtcagagag ggggaaccgc cgtcccaaca tcacaaaaag 500

 tgaaagaagc cggaagagat tttacctatt taatagtggt gctttttgga 550

 atcagcatta caggtggctt gttttacacg attttcaaag aacttttttc 600

 ttcatccagt cctagcaaga tatatgggag agccttagaa aaatgcagat 650

 cacatcctga ggtgatcggt gtctttggtg agtctgttaa aggctatggg 700

 gaggtgacaa ggcggggtcg ccggcagcat gtcaggttca ctgaatatgt 750

 aaaagatggg ctgaaacaca cgtgtgtgaa attctacatt gagggctctg 800

 agccagggaa gcaaggaacg gtgtatgcgc aagtgaaaga gaacccagga 850

 agtggtgaat atgattttcg atatatattt gtagaaattg aatcttatcc 900

 tagaagaact attatcattg aagataatcg atcccaagat gattaataat 950

 caagcaagca ggtttctgat ggatgttgaa tggcgtggac tcgctactcc 1000

 gttcttcaca gctgccttcc agaatgtgtt caaaagaaag acaagaagga 1050

 gtgtatggct tataaagtga atctaataca gtatttgttg catttaaaca 1100

 aactagacat tttcttacgg aaaaattatg aaatacagca tattttatgt 1150

 tctcccattg actcaatcat gacaatattt ctgctttaac accatctttc 1200

 gtgattagaa atgtttgtta ttggaaatgt tacaccatgt aaataaagga 1250

 aatagatttt agtattgtat tcattttata ttatagaact gcataatgtc 1300

 tgcagaataa aattaaaact aacaaataaa aaaaaaaaaa aaa 1343

<210> 3854
<211> 248
<212> PRT
<213> Homo sapien

<400> 3854
 Met Ile Cys Thr Phe Leu Arg Ala Val Gln Tyr Thr Glu Lys Leu
   1               5                  10                  15

 His Arg Ser Ser Ala Lys Arg Leu Leu Leu Pro Tyr Ile Val Leu
                  20                  25                  30

 Asn Lys Ala Tyr Leu Lys Thr Glu Pro Ser Leu Arg Cys Gly Leu
                  35                  40                  45

 Gln Tyr Gln Lys Lys Thr Leu Arg Pro Arg Cys Ile Leu Gly Val
                  50                  55                  60

 Thr Gln Lys Thr Ile Trp Thr Gln Gly Pro Ser Pro Arg Lys Ala
                  65                  70                  75

 Lys Glu Asp Gly Ser Lys Gln Val Ser Val His Arg Ser Gln Arg
                  80                  85                  90

 Gly Gly Thr Ala Val Pro Thr Ser Gln Lys Val Lys Glu Ala Gly
                  95                 100                 105

 Arg Asp Phe Thr Tyr Leu Ile Val Val Leu Phe Gly Ile Ser Ile
                 110                 115                 120

 Thr Gly Gly Leu Phe Tyr Thr Ile Phe Lys Glu Leu Phe Ser Ser
                 125                 130                 135

 Ser Ser Pro Ser Lys Ile Tyr Gly Arg Ala Leu Glu Lys Cys Arg
                 140                 145                 150

 Ser His Pro Glu Val Ile Gly Val Phe Gly Glu Ser Val Lys Gly
                 155                 160                 165

 Tyr Gly Glu Val Thr Arg Arg Gly Arg Arg Gln His Val Arg Phe
                 170                 175                 180

 Thr Glu Tyr Val Lys Asp Gly Leu Lys His Thr Cys Val Lys Phe
                 185                 190                 195

 Tyr Ile Glu Gly Ser Glu Pro Gly Lys Gln Gly Thr Val Tyr Ala
                 200                 205                 210

 Gln Val Lys Glu Asn Pro Gly Ser Gly Glu Tyr Asp Phe Arg Tyr
                 215                 220                 225

 Ile Phe Val Glu Ile Glu Ser Tyr Pro Arg Arg Thr Ile Ile Ile
                 230                 235                 240

 Glu Asp Asn Arg Ser Gln Asp Asp
                 245

<210> 3855
<211> 2000
<212> DNA
<213> Homo sapien

<400> 3855
 ctgcacggag tgtccactgt tcacggacca ggccacggta gagcgctttg 50

 ggaaggagca cgcagtcatc atcctcaacc acaacttcga gatcgacttc 100

 ctctgtgggt ggaccatgtg tgagcgcttc ggagtgctgg ggagctccaa 150

 ggtcctcgct aagaaggagc tgctctacgt gcccctcatc ggctggacgt 200

 ggtactttct ggagattgtg ttctgcaagc ggaagtggga ggaggaccgg 250

 gacaccgtgg tcgaagggct gaggcgcctg tcggactacc ccgagtacat 300

 gtggtttctc ctgtactgcg aggggacgcg cttcacggag accaagcacc 350

 gcgttagcat ggaggtggcg gctgctaagg ggcttcctgt cctcaagtac 400

 cacctgctgc cgcggaccaa gggcttcacc accgcagtca agtgcctccg 450

 ggggacagtc gcagctgtct atgatgtaac cctgaacttc agaggaaaca 500

 agaacccgtc cctgctgggg atcctctacg ggaagaagta cgaggcggac 550

 atgtgcgtga ggagatttcc tctggaagac atcccgctgg atgaaaagga 600

 agcagctcag tggcttcata aactgtacca ggagaaggga cgcgctccag 650

 gagatatata atcagaaggg catgtttcca ggggagcagt ttaagcctgc 700

 ccggaggccg tggaccctcc tgaacttcct gtcctgggcc accattctcc 750

 tgtctcccct cttcagtttc gtcttgggcg tctttgccag cggatcacct 800

 ctcctgatcc tgactttctt ggggtttgtg ggagcagctt cctttggagt 850

 tcgcagactg ataggagtaa ctgagataga aaaaggctcc agctacggaa 900

 accaagagtt taagaaaaag gaataattaa tggctgtgac tgaacacacg 950

 cggccctgac ggtggtatcc agttaactca aaaccaacac acagagtgca 1000

 ggaaaagaca attagaaact atttttctta ttaactggtg actaatatta 1050

 acaaaacttg agccaagagt aaagaattca gaaggcctgt caggtgaagt 1100

 cttcagcctc ccacagcgca gggtcccagc atctccacgc gcgcccgtgg 1150

 gaggtgggtc cggccggaga ggcctcccgc ggacgccgtc tctccagaac 1200

 tccgcttcca agagggagcc tttggctgct ttctctcctt aaacttagat 1250

 caaatttttt ggtttttaat cagttatctt gggaacttaa cctggcccct 1300

 cacctcttct gcaccccccg cccccgaaac tgtctcgtaa tgaatttctg 1350

 ctgtcctcct gggagtggac ggccgggtcc cgtcccccgg gagcatcgct 1400

 cggctcagca ccttggctcc cagtgggggc cccgtggagg gcgcccgtag 1450

 tgataagcac accggcacga acgtcaggtc cattcctcga agtcggagcc 1500

 ctcactctgc ctgtcctggg gctggctgag ggcgaacgcc ccacctcact 1550

 ttctagagcc ctgtctgtcc tagctcctat ctgaccttgt gtgtaaatac 1600

 gtacatctgt ttttaaagtg gatgggcccc tgagaactca gtgaaatgca 1650

 gagttctcca tgcacctaaa gcttctttgt cgctctcatg gctgtcagat 1700

 cctggtccct ccacactggg tgctggggag ggaggaccct cggggctacc 1750

 gcgcgccccc ccatcccaca gatcaggagc caaggaggga gaacagggca 1800

 gcctgtggga ctctaggatg cttcagaaga agcgacggca ccgtcaaccc 1850

 ctctgttttt taaaggtggt tggagactgt taacactgag ctcattgact 1900

 tctagagatt ttatttttac tggttgatct cttggtggtt ttcaacttcc 1950

 tgctggaaac tagaggtggg gcacccccca ccccccagcc tcgcactgtg 2000

<210> 3856
<211> 111
<212> PRT
<213> Homo sapien

<400> 3856
 Met Lys Arg Lys Gln Leu Ser Gly Phe Ile Asn Cys Thr Arg Arg
   1               5                  10                  15

 Arg Asp Ala Leu Gln Glu Ile Tyr Asn Gln Lys Gly Met Phe Pro
                  20                  25                  30

 Gly Glu Gln Phe Lys Pro Ala Arg Arg Pro Trp Thr Leu Leu Asn
                  35                  40                  45

 Phe Leu Ser Trp Ala Thr Ile Leu Leu Ser Pro Leu Phe Ser Phe
                  50                  55                  60

 Val Leu Gly Val Phe Ala Ser Gly Ser Pro Leu Leu Ile Leu Thr
                  65                  70                  75

 Phe Leu Gly Phe Val Gly Ala Ala Ser Phe Gly Val Arg Arg Leu
                  80                  85                  90

 Ile Gly Val Thr Glu Ile Glu Lys Gly Ser Ser Tyr Gly Asn Gln
                  95                 100                 105

 Glu Phe Lys Lys Lys Glu
                 110

<210> 3857
<211> 729
<212> DNA
<213> Homo sapien

<400> 3857
 ctccaacgct gggtgacatt gagctcacca gcgccaccgt ccccggcgaa 50

 gttctgcgct ggtcggcgga gtagcaagtg gccatgggga gcctcagcgg 100

 tctgcgcctg gcagcaggaa gctgttttag gttatgtgaa agagatgttt 150

 cctcatctct aaggcttacc agaagctctg atttgaagag aataaatgga 200

 ttttgcacaa aaccacagga aagtcccgga gctccatccc gcacttacaa 250

 cagagtgcct ttacacaaac ctacggattg gcagaaaaag atcctcatat 300

 ggtcaggtcg cttcaaaaag gaagatgaaa tcccagagac tgtctcgttg 350

 gagatgcttg atgctgcaaa gaacaagatg cgagtgaaga tcagctatct 400

 aatgattgcc ctgacggtgg taggatgcat cttcatggtt attgagggca 450

 agaaggctgc ccaaagacac gagactttaa caagcttgaa cttagaaaag 500

 aaagctcgtc tgaaagagga agcagctatg aaggccaaaa cagagtagca 550

 gaggtatccg tgttggctgg attttgaaaa tccaggaatt atgttataac 600

 gtgcctgtat taaaaaggat gtggtatgag gatccatttc ataaagtatg 650

 atttgcccaa acctgtacca tttccgtatt tctgctgtag aagtagaaat 700

 aaattttctt aaataaaaaa aaaaaaaaa 729

<210> 3858
<211> 154
<212> PRT
<213> Homo sapien

<400> 3858
 Met Gly Ser Leu Ser Gly Leu Arg Leu Ala Ala Gly Ser Cys Phe
   1               5                  10                  15

 Arg Leu Cys Glu Arg Asp Val Ser Ser Ser Leu Arg Leu Thr Arg
                  20                  25                  30

 Ser Ser Asp Leu Lys Arg Ile Asn Gly Phe Cys Thr Lys Pro Gln
                  35                  40                  45

 Glu Ser Pro Gly Ala Pro Ser Arg Thr Tyr Asn Arg Val Pro Leu
                  50                  55                  60

 His Lys Pro Thr Asp Trp Gln Lys Lys Ile Leu Ile Trp Ser Gly
                  65                  70                  75

 Arg Phe Lys Lys Glu Asp Glu Ile Pro Glu Thr Val Ser Leu Glu
                  80                  85                  90

 Met Leu Asp Ala Ala Lys Asn Lys Met Arg Val Lys Ile Ser Tyr
                  95                 100                 105

 Leu Met Ile Ala Leu Thr Val Val Gly Cys Ile Phe Met Val Ile
                 110                 115                 120

 Glu Gly Lys Lys Ala Ala Gln Arg His Glu Thr Leu Thr Ser Leu
                 125                 130                 135

 Asn Leu Glu Lys Lys Ala Arg Leu Lys Glu Glu Ala Ala Met Lys
                 140                 145                 150

 Ala Lys Thr Glu


<210> 3859
<211> 3327
<212> DNA
<213> Homo sapien

<400> 3859
 tccagcacca aagcggccgt tctcggattc cggagcgttc tggagccccg 50

 agagacgccc cggggttcta gaagctcccc ggcggcgccc agtcccggct 100

 tcattcgggc gtccctccga aacccactcg ggtgcacggg tcgtcggcga 150

 gccgcgaccg ggtcctggcg cgcaccatga tcgtggcgga ctccgagtgc 200

 cgcgcagagc tcaaggacta cctgcggttc gccccgggcg gcgtcggcga 250

 ctcgggcccc ggagaggagc agagggagag ccgggctcgg cgaggccctc 300

 gagggcccag cgccttcatc cccgtggagg aggtccttcg ggagggggct 350

 gagagcctcg agcagcacct ggggctggag gcactgatgt cctctgggcg 400

 agtagacaac ctggcagtgg tgatgggcct gcaccctgac tactttacca 450

 gcttctggcg cctgcactac ctgctgctgc acacggatgg tcccttggcc 500

 agctcctggc gccactacat tgccatcatg gctgccgccc gccatcagtg 550

 ttcttacctg gtaggctccc acatggccga gtttctgcag actggtggtg 600

 accctgagtg gctgctgggc ctccaccggg cccccgagaa gctgcgcaaa 650

 ctcagcgaga tcaacaagtt gctggcgcat cggccatggc tcatcaccaa 700

 ggaacacatc caggccttgc tgaagaccgg cgagcacact tggtccctgg 750

 ccgagctcat tcaggctctg gtcctgctca cccactgcca ctcgctctcc 800

 tccttcgtgt ttggctgtgg catcctccct gagggggatg cagatggcag 850

 ccctgccccc caggcaccta caccccctag tgaacagagc agccccccaa 900

 gcagggaccc gttgaacaac tctgggggct ttgagtctgc ccgcgacgtg 950

 gaggcgctga tggagcgcat gcagcagctg caggagagcc tgctgcggga 1000

 tgaggggacg tcccaggagg agatggagag ccgctttgag ctggagaagt 1050

 cagagagcct gctggtgacc ccctcagctg acatcctgga gccctctcca 1100

 cacccagaca tgctgtgctt tgtggaagac cctactttcg gatatgagga 1150

 cttcactcgg agaggggctc aggcaccccc taccttccgg gcccaggatt 1200

 atacctggga agaccatggc tactcgctga tccagcggct ttaccctgag 1250

 ggtgggcagc tgctggatga gaagttccag gcagcctata gcctcaccta 1300

 caataccatc gccatgcaca gtggtgtgga cacctccgtg ctccgcaggg 1350

 ccatctggaa ctatatccac tgcgtctttg gcatcagata tgatgactat 1400

 gattatgggg aggtgaacca gctcctggag cggaacctca aggtctatat 1450

 caagacagtg gcctgctacc cagagaagac cacccgaaga atgtacaacc 1500

 tcttctggag gcacttccgc cactcagaga aggtccacgt gaacttgctg 1550

 ctcctggagg cgcgcatgca agccgctctg ctgtacgccc tccgtgccat 1600

 cacccgctac atgacctgac tcctgagcag gacctgggcc cggttcagct 1650

 ccccacaagg acttctctgt ctggagacag ccccagaccc ttttgtgtcc 1700

 catgcccacc ctccccacgc tgcagtgggc ttgtgtgtga tgtgcagtcc 1750

 cgaagccaca ccctcccttt tcctcactgg aatggacagt tcattgcact 1800

 gactctggga tctcagccct gctcctggga gctggaagag cacttggaga 1850

 tcctaaggga ccacaccctt cctccttccc ctgcccacag aggcagaggg 1900

 cacaggaaag aagccgggcc aagctcggaa ttaatgtgcc acaagtgttg 1950

 tggccttcct gaactgggaa gtccctggct ggcccccggg ggagaggggc 2000

 aaatgcctcc gggactgaca ctccaggcag ctttgccttc tctcccctgt 2050

 catttccaga tttcattacc tcctacttgc cattcaccca tcaatgtgaa 2100

 agtcagggtc acagctggtc tgtgtgtcca gttccctaaa agcctgttct 2150

 gttgggcagc ctgaggctgt tgcccgaatc ctagttcagt tttttgactt 2200

 cctttgccct ttttcccttt tctccatgct taatggtgtg aggcgtcagg 2250

 agagaggcca agtacataaa aaaaaaaaaa agcagattat ctctagagag 2300

 tttgagcctt tgctggtcac attgccttct gaagaggagg gagtattaga 2350

 ttataaatcc tctttatttt ggtcctttat gcttgaggtt ccaacctgga 2400

 gccacagtgt gtgagaggag gaggagaggg agaattctgt tctcccagag 2450

 ctgcacctgc ctcgcagagg ccagcacccc actctcctgc ctccagtggc 2500

 cctgccgcag atgtctccca aaaagttgag cctttctaga tggcttaggt 2550

 ggcaccatgg ctcagcagga ggggcgggag gcaccagggt tcttgtttgg 2600

 accctgcccc tgggccatgg ccaggtgacc atggctacat tgccaaacct 2650

 ctgactgcca cagctgcaga ctgagagggt gggtctgagt ccccacaatg 2700

 tctgaagctg cccctgggat tctcaggcca acctgccaac agcaagcgga 2750

 ttttcttgca agatcaggga ccccatttct gcagccagtg tctcctgggt 2800

 gccttctgag gactcccacc cccatcccag tatctcatct gtcccctctc 2850

 ctggggctta agtgggttgc ttccaggcag aagcagccaa ggaccgattc 2900

 caggcacttt ctgtagcaaa tgactgtgaa ttacgacttc tcttgccctt 2950

 cttctagcag tctgtgcctc ctctctgacc agtttggagg gcactgaaga 3000

 aaggcaaggg ccgtgctgct gctgggcggg gcaggagagg agcctggcca 3050

 gtgtgccaca ttaaataccc gtgcaggcgc ggagaagcaa ccggcacccc 3100

 cttccggcct gaaagccctc cctgcaagaa ggtgtgcagg agagaagagg 3150

 ccccggcatg gggatctggg ttctagaggg catgtgatga ctgtaaatgt 3200

 tcactgggtg ggtagggagt ggtatccagt gttcaagtgc agaaatcttt 3250

 ggctttgcta ccagttccat atgatgagaa ataaacgttc gctgaggttt 3300

 tgtttcataa aaaaaaaaaa aaaaaaa 3327

<210> 3860
<211> 480
<212> PRT
<213> Homo sapien

<400> 3860
 Met Ile Val Ala Asp Ser Glu Cys Arg Ala Glu Leu Lys Asp Tyr
   1               5                  10                  15

 Leu Arg Phe Ala Pro Gly Gly Val Gly Asp Ser Gly Pro Gly Glu
                  20                  25                  30

 Glu Gln Arg Glu Ser Arg Ala Arg Arg Gly Pro Arg Gly Pro Ser
                  35                  40                  45

 Ala Phe Ile Pro Val Glu Glu Val Leu Arg Glu Gly Ala Glu Ser
                  50                  55                  60

 Leu Glu Gln His Leu Gly Leu Glu Ala Leu Met Ser Ser Gly Arg
                  65                  70                  75

 Val Asp Asn Leu Ala Val Val Met Gly Leu His Pro Asp Tyr Phe
                  80                  85                  90

 Thr Ser Phe Trp Arg Leu His Tyr Leu Leu Leu His Thr Asp Gly
                  95                 100                 105

 Pro Leu Ala Ser Ser Trp Arg His Tyr Ile Ala Ile Met Ala Ala
                 110                 115                 120

 Ala Arg His Gln Cys Ser Tyr Leu Val Gly Ser His Met Ala Glu
                 125                 130                 135

 Phe Leu Gln Thr Gly Gly Asp Pro Glu Trp Leu Leu Gly Leu His
                 140                 145                 150

 Arg Ala Pro Glu Lys Leu Arg Lys Leu Ser Glu Ile Asn Lys Leu
                 155                 160                 165

 Leu Ala His Arg Pro Trp Leu Ile Thr Lys Glu His Ile Gln Ala
                 170                 175                 180

 Leu Leu Lys Thr Gly Glu His Thr Trp Ser Leu Ala Glu Leu Ile
                 185                 190                 195

 Gln Ala Leu Val Leu Leu Thr His Cys His Ser Leu Ser Ser Phe
                 200                 205                 210

 Val Phe Gly Cys Gly Ile Leu Pro Glu Gly Asp Ala Asp Gly Ser
                 215                 220                 225

 Pro Ala Pro Gln Ala Pro Thr Pro Pro Ser Glu Gln Ser Ser Pro
                 230                 235                 240

 Pro Ser Arg Asp Pro Leu Asn Asn Ser Gly Gly Phe Glu Ser Ala
                 245                 250                 255

 Arg Asp Val Glu Ala Leu Met Glu Arg Met Gln Gln Leu Gln Glu
                 260                 265                 270

 Ser Leu Leu Arg Asp Glu Gly Thr Ser Gln Glu Glu Met Glu Ser
                 275                 280                 285

 Arg Phe Glu Leu Glu Lys Ser Glu Ser Leu Leu Val Thr Pro Ser
                 290                 295                 300

 Ala Asp Ile Leu Glu Pro Ser Pro His Pro Asp Met Leu Cys Phe
                 305                 310                 315

 Val Glu Asp Pro Thr Phe Gly Tyr Glu Asp Phe Thr Arg Arg Gly
                 320                 325                 330

 Ala Gln Ala Pro Pro Thr Phe Arg Ala Gln Asp Tyr Thr Trp Glu
                 335                 340                 345

 Asp His Gly Tyr Ser Leu Ile Gln Arg Leu Tyr Pro Glu Gly Gly
                 350                 355                 360

 Gln Leu Leu Asp Glu Lys Phe Gln Ala Ala Tyr Ser Leu Thr Tyr
                 365                 370                 375

 Asn Thr Ile Ala Met His Ser Gly Val Asp Thr Ser Val Leu Arg
                 380                 385                 390

 Arg Ala Ile Trp Asn Tyr Ile His Cys Val Phe Gly Ile Arg Tyr
                 395                 400                 405

 Asp Asp Tyr Asp Tyr Gly Glu Val Asn Gln Leu Leu Glu Arg Asn
                 410                 415                 420

 Leu Lys Val Tyr Ile Lys Thr Val Ala Cys Tyr Pro Glu Lys Thr
                 425                 430                 435

 Thr Arg Arg Met Tyr Asn Leu Phe Trp Arg His Phe Arg His Ser
                 440                 445                 450

 Glu Lys Val His Val Asn Leu Leu Leu Leu Glu Ala Arg Met Gln
                 455                 460                 465

 Ala Ala Leu Leu Tyr Ala Leu Arg Ala Ile Thr Arg Tyr Met Thr
                 470                 475                 480

<210> 3861
<211> 3290
<212> DNA
<213> Homo sapien

<400> 3861
 cgtccagcgg tcgtgttgcc atgggccgga ggagagcccc ggccggtggg 50

 tcgctgggac gggcccttat gcgccatcag actcagcgga gccgaagcca 100

 tcgtcacact gactcctggt tgcacacaag tgaactcaat gatggctatg 150

 attggggtcg tcttaatctt cagtcagtga ctgaacagag ctcccttgat 200

 gacttccttg ctactgcaga acttgcagga acagagtttg tagctgaaaa 250

 acttaatatt aagtttgtgc ctgctgaggc tagaactgga ctactgtctt 300

 tcgaggagag ccagagaatt aagaagctcc atgaagaaaa caaacagttc 350

 ttgtgtatac cgaggagacc aaactggaac caaaatacta ccccagaaga 400

 actcaaacaa gcagagaaag ataactttct agaatggaga cgtcagcttg 450

 tccggctaga agaggaacag aagctgatat tgactccatt tgaacgaaat 500

 ttggactttt ggcgccagct ctggagagtc attgagagaa gtgatattgt 550

 ggtccagata gtagatgctc gaaacccact cctgtttaga tgtgaggatt 600

 tggaatgtta tgtgaaagaa atggatgcca ataaggagaa cgtcattctg 650

 atcaacaagg cagacttgct gactgctgag cagcggagtg cctgggccat 700

 gtacttcgaa aaagaagatg tgaaggttat tttctggtca gctttggccg 750

 gagccattcc cctgaatggt gactctgagg aagaggcaaa cagagatgat 800

 agacaaagca acacaactga gtttggacat tccagtttcg accaggctga 850

 aatttcccac agtgaatccg aacatctccc agctagggat tctccttcac 900

 ttagtgaaaa tcccacaacg gatgaagatg acagtgagta tgaggactgt 950

 ccagaggagg aggaagacga ctggcagacg tgctcagaag aagacggtcc 1000

 caaggaagag gactgcagcc aggactggaa ggaaagctct actgcagatt 1050

 ctgaggctcg gagcaggaaa accccacaga agaggcagat acacaatttt 1100

 agccatctgg tatccaagca ggagttactg gagctcttta aggagctaca 1150

 cactgggaga aaggtgaaag atgggcaact tacggtcgga ctggtgggct 1200

 accctaatgt tggtaagagt tcaacaatca acaccatcat gggcaacaag 1250

 aaagtatctg tgtctgccac acctggtcac acaaagcact ttcagactct 1300

 ctatgtggag cctggcctct gcctgtgtga ctgtcctggc ttggtgatgc 1350

 catcttttgt gtctaccaag gcagaaatga cttgcagcgg aatcctccca 1400

 attgatcaga tgagagatca tgttcctcct gtatcactag tttgccagaa 1450

 tattccaaga catgttttag aagctaccta tggcattaac atcataacgc 1500

 ctagagagga tgaagatccc caccgacctc caacatcgga agaactgttg 1550

 acagcttatg gatacatgcg aggattcatg acagcgcatg gacagccaga 1600

 ccagcctcga tctgcgcgct acatcctgaa ggactatgtc agtggtaagc 1650

 tgctgtactg ccatcctcct cctggaagag atcctgtaac ttttcagcat 1700

 caacaccagc gactcctaga gaacaaaatg aacagtgatg aaataaaaat 1750

 gcagctaggc agaaataaaa aagcaaagca gattgaaaat atcgttgaca 1800

 aaactttttt ccatcaagag aatgtgaggg ctttgaccaa aggagtccag 1850

 gctgtgatgg gttacaagcc cgggagtggt gtagtgactg catccactgc 1900

 gagctctgag aacggggcgg ggaagccctg gaaaaaacat ggcaacagaa 1950

 ataaaaaaga aaaaagtcgt agactctaca agcacctgga tatgtgaggt 2000

 tgggctgcaa cagaaatgtc atctgcattg tgcagatgga aaagagcaga 2050

 agctgcctgt tgcctgtgga actgtcccaa gacactagca ctgtagaacg 2100

 ggccctgctc ttgcagagca cggctgcacc caacagtctc catgtcaaga 2150

 ccaagggcct cctggaaaca ccagctctga caaaaaggag tcatctggga 2200

 gcccgagaat cctactcctg gccgggcaca gtggctcacg caccaacatg 2250

 gagaaacccc gtctctacta aaaatacaaa aaaattagcc aggcgtggtg 2300

 gcgcgcacct gtaatcccag ctactcggga ggctgaggca ggagaatcac 2350

 ttgaaccagg gaggcagagt ttgcagtgaa tggagattgc gccgctgcac 2400

 tccagcctgg gcgacagagt gagactgcat cacaagaaaa aaaatttgca 2450

 agggatggtt cacgagacac atttgggacg aaggtgaaag agaaattccc 2500

 cattctgagt gtcctagttg ggttcctccg actctaaaca agggacttgg 2550

 gttcagttag tgtacagcgg gggctcacgt ccactaagga acatgtagaa 2600

 tgtaaccacc gggtgacagg gaagctgcgg tatttactac ctagccccca 2650

 tcttcactgg ttattccact tatttaaaat gtccagaata agcaaatctc 2700

 catatagagg aagtagatta gtggttgctt cgggatggga ggaatgggaa 2750

 gattgaggtc tttcttttgc agtgataaaa atgtcctaaa attgactgta 2800

 gcgatggtca cacaactctg aatatgctta agaccattga attacacact 2850

 ttacgttggt gaattgtatg gtatgtaaat tatagttcaa taacatagtt 2900

 acaaaagata atcaaaagca tgaaagcact attgatgtgg tttggatctg 2950

 tgtcctcacc gagtctcatg ttgaaatgta agccccctgg tgggaggcga 3000

 tgggattatg gggcagagtc ctcacaaacg gtttagcacc acccgctcag 3050

 tgctgttctc ctgatattga gtcctcatca catctggttg cttcaaagtg 3100

 tgtggtgcct cccctctgtc tccctcctgc tctggccata taagatgtgc 3150

 ctgcttctcc ttcgccttct aacatgattg taagtttcct gaggcctccc 3200

 tagaagcaaa agctgctgtg cttcctgtac catctactgg accgtgagcc 3250

 aattaaacct cttttcttta taaaaaaaaa aaaaaaaagg 3290

<210> 3862
<211> 658
<212> PRT
<213> Homo sapien

<400> 3862
 Met Gly Arg Arg Arg Ala Pro Ala Gly Gly Ser Leu Gly Arg Ala
   1               5                  10                  15

 Leu Met Arg His Gln Thr Gln Arg Ser Arg Ser His Arg His Thr
                  20                  25                  30

 Asp Ser Trp Leu His Thr Ser Glu Leu Asn Asp Gly Tyr Asp Trp
                  35                  40                  45

 Gly Arg Leu Asn Leu Gln Ser Val Thr Glu Gln Ser Ser Leu Asp
                  50                  55                  60

 Asp Phe Leu Ala Thr Ala Glu Leu Ala Gly Thr Glu Phe Val Ala
                  65                  70                  75

 Glu Lys Leu Asn Ile Lys Phe Val Pro Ala Glu Ala Arg Thr Gly
                  80                  85                  90

 Leu Leu Ser Phe Glu Glu Ser Gln Arg Ile Lys Lys Leu His Glu
                  95                 100                 105

 Glu Asn Lys Gln Phe Leu Cys Ile Pro Arg Arg Pro Asn Trp Asn
                 110                 115                 120

 Gln Asn Thr Thr Pro Glu Glu Leu Lys Gln Ala Glu Lys Asp Asn
                 125                 130                 135

 Phe Leu Glu Trp Arg Arg Gln Leu Val Arg Leu Glu Glu Glu Gln
                 140                 145                 150

 Lys Leu Ile Leu Thr Pro Phe Glu Arg Asn Leu Asp Phe Trp Arg
                 155                 160                 165

 Gln Leu Trp Arg Val Ile Glu Arg Ser Asp Ile Val Val Gln Ile
                 170                 175                 180

 Val Asp Ala Arg Asn Pro Leu Leu Phe Arg Cys Glu Asp Leu Glu
                 185                 190                 195

 Cys Tyr Val Lys Glu Met Asp Ala Asn Lys Glu Asn Val Ile Leu
                 200                 205                 210

 Ile Asn Lys Ala Asp Leu Leu Thr Ala Glu Gln Arg Ser Ala Trp
                 215                 220                 225

 Ala Met Tyr Phe Glu Lys Glu Asp Val Lys Val Ile Phe Trp Ser
                 230                 235                 240

 Ala Leu Ala Gly Ala Ile Pro Leu Asn Gly Asp Ser Glu Glu Glu
                 245                 250                 255

 Ala Asn Arg Asp Asp Arg Gln Ser Asn Thr Thr Glu Phe Gly His
                 260                 265                 270

 Ser Ser Phe Asp Gln Ala Glu Ile Ser His Ser Glu Ser Glu His
                 275                 280                 285

 Leu Pro Ala Arg Asp Ser Pro Ser Leu Ser Glu Asn Pro Thr Thr
                 290                 295                 300

 Asp Glu Asp Asp Ser Glu Tyr Glu Asp Cys Pro Glu Glu Glu Glu
                 305                 310                 315

 Asp Asp Trp Gln Thr Cys Ser Glu Glu Asp Gly Pro Lys Glu Glu
                 320                 325                 330

 Asp Cys Ser Gln Asp Trp Lys Glu Ser Ser Thr Ala Asp Ser Glu
                 335                 340                 345

 Ala Arg Ser Arg Lys Thr Pro Gln Lys Arg Gln Ile His Asn Phe
                 350                 355                 360

 Ser His Leu Val Ser Lys Gln Glu Leu Leu Glu Leu Phe Lys Glu
                 365                 370                 375

 Leu His Thr Gly Arg Lys Val Lys Asp Gly Gln Leu Thr Val Gly
                 380                 385                 390

 Leu Val Gly Tyr Pro Asn Val Gly Lys Ser Ser Thr Ile Asn Thr
                 395                 400                 405

 Ile Met Gly Asn Lys Lys Val Ser Val Ser Ala Thr Pro Gly His
                 410                 415                 420

 Thr Lys His Phe Gln Thr Leu Tyr Val Glu Pro Gly Leu Cys Leu
                 425                 430                 435

 Cys Asp Cys Pro Gly Leu Val Met Pro Ser Phe Val Ser Thr Lys
                 440                 445                 450

 Ala Glu Met Thr Cys Ser Gly Ile Leu Pro Ile Asp Gln Met Arg
                 455                 460                 465

 Asp His Val Pro Pro Val Ser Leu Val Cys Gln Asn Ile Pro Arg
                 470                 475                 480

 His Val Leu Glu Ala Thr Tyr Gly Ile Asn Ile Ile Thr Pro Arg
                 485                 490                 495

 Glu Asp Glu Asp Pro His Arg Pro Pro Thr Ser Glu Glu Leu Leu
                 500                 505                 510

 Thr Ala Tyr Gly Tyr Met Arg Gly Phe Met Thr Ala His Gly Gln
                 515                 520                 525

 Pro Asp Gln Pro Arg Ser Ala Arg Tyr Ile Leu Lys Asp Tyr Val
                 530                 535                 540

 Ser Gly Lys Leu Leu Tyr Cys His Pro Pro Pro Gly Arg Asp Pro
                 545                 550                 555

 Val Thr Phe Gln His Gln His Gln Arg Leu Leu Glu Asn Lys Met
                 560                 565                 570

 Asn Ser Asp Glu Ile Lys Met Gln Leu Gly Arg Asn Lys Lys Ala
                 575                 580                 585

 Lys Gln Ile Glu Asn Ile Val Asp Lys Thr Phe Phe His Gln Glu
                 590                 595                 600

 Asn Val Arg Ala Leu Thr Lys Gly Val Gln Ala Val Met Gly Tyr
                 605                 610                 615

 Lys Pro Gly Ser Gly Val Val Thr Ala Ser Thr Ala Ser Ser Glu
                 620                 625                 630

 Asn Gly Ala Gly Lys Pro Trp Lys Lys His Gly Asn Arg Asn Lys
                 635                 640                 645

 Lys Glu Lys Ser Arg Arg Leu Tyr Lys His Leu Asp Met
                 650                 655

<210> 3863
<211> 3869
<212> DNA
<213> Homo sapien

<400> 3863
 gagccggtgg cgcaggtgtc ggggtcctcg agcgcccagc ctgggagcat 50

 gattgtggac aagctgctgg acgacagccg cggcggagag gggctgcggg 100

 acgcggcggg cggctgcggc ctcatgacca gcccgctcaa cctgagctac 150

 ttctacggcg cgtcgccgcc cgccgccgcc ccgggcgcct gcgacgccag 200

 ctgctcggtc ttgggcccct cggcgcccgg ctcgcccggc tccgactcct 250

 ccgacttctc ctctgcctcg tcggtgtcct cctgcggcgc cgtggagtcc 300

 cggtcgagag gcggcgcccg cgccgagcgc cagccagttg agccccatat 350

 gggggttggc aggcagcaga gaggcccctt tcaaggtgtt cgggtaaaga 400

 actcagtgaa ggaactcctg ttgcacatcc gaagtcataa acagaaggct 450

 tctggccaag ctgtggatga ttttaagaca caaggtgtga acatagaaca 500

 gttcagagaa ttgaagaaca cagtatcata cagtgggaaa aggaaagggc 550

 ccgattcgtt gtctgatgga cctgcttgca aaaggccagc tctgttgcat 600

 tcccaatttt tgacaccacc tcaaacacca acgcccgggg agagcatgga 650

 agatgttcat ctcaatgaac ccaaacagga gagcagtgct gatctgcttc 700

 agaacattat caacattaag aatgaatgca gccccgtttc cctgaacaca 750

 gttcaagtta gctggctgaa ccccgtggtg gtccctcaga gctcccccgc 800

 agagcagtgt caggacttcc atggagggca ggtcttttct ccacctcaga 850

 aatgccaacc attccaagtc aggggctccc aacaaatgat agaccaggct 900

 tccctgtacc agtattctcc acagaaccag catgtagagc agcagccaca 950

 ctacacccac aaaccaactc tggaatacag tccttttccc atacctcccc 1000

 agtcccccgc ttatgaacca aacctctttg atggtccaga atcacagttt 1050

 tgcccaaacc aaagcttagt ttcccttctt ggtgatcaaa gggaatctga 1100

 gaatattgct aatcccatgc agacttcctc cagtgttcag cagcaaaatg 1150

 atgctcactt gcacagcttc agcatgatgc ccagcagcgc ctgtgaggcc 1200

 atggtggggc acgagatggc ctctgactct tcaaacactt cactgccatt 1250

 ctcaaacatg ggaaatccaa tgaacaccac acagttaggg aaatcacttt 1300

 ttcagtggca ggtggagcag gaagaaagca aattggcaaa tatttcccaa 1350

 gaccagtttc tttcaaagga tgcagatggt gacacgttcc ttcatattgc 1400

 tgttgcccaa gggagaaggg cactttccta tgttcttgca agaaagatga 1450

 atgcacttca catgctggat attaaagagc acaatggaca gagtgccttt 1500

 caggtggcag tggctgccaa tcagcatctc attgtgcagg atctggtgaa 1550

 catcggggca caggtgaaca ccacagactg ctggggaaga acacctctgc 1600

 atgtgtgtgc tgagaagggc cactcccagg tgcttcaggc gattcagaag 1650

 ggagcagtgg gaagtaatca gtttgtggat cttgaggcaa ctaactatga 1700

 tggcctgact ccccttcact gtgcagtcat agcccacaat gctgtggtcc 1750

 atgaactcca gagaaatcaa cagcctcatt cacctgaagt tcaggagctt 1800

 ttactgaaga ataagagtct ggttgatacc attaagtgcc taattcaaat 1850

 gggagcagcg gtggaagcga aggatcgcaa aagtggccgc acagccctgc 1900

 atttggcagc tgaagaagca aatctggaac tcattcgcct ctttttggag 1950

 ctgcccagtt gcctgtcttt tgtgaatgca aaggcttaca atggcaacac 2000

 tgccctccat gttgctgcca gcttgcagta tcggttgaca caattagatg 2050

 ctgtccgcct gttgatgagg aagggagcag acccaagtac tcggaacttg 2100

 gagaacgaac agccagtgca tttggttccc gatggccctg tgggagaaca 2150

 gatccgacgt atcctgaagg gaaagtccat tcagcagaga gctccaccgt 2200

 attagctcca ttagcttgga gcctggctag caacactcac tgtcagttag 2250

 gcagtcctga tgtatctgta catagaccat ttgccttata ttggcaaatg 2300

 taagttgttt ctatgaaaca aacatattta gttcactatt atatagtggg 2350

 ttatattaaa agaaaagaag aaaaatatct aatttctctt ggcagatttg 2400

 catatttcat acccaggtat ctgggatcta gacatctgaa tttgatctca 2450

 atggtaacat tgccttcaat taacagtagc ttttgagtag gaaaggactt 2500

 tgatttgtgg cacaaaacat tattaatata gctattgaca gtttcaaagc 2550

 aggtaaattg taaatgtttc tttaagaaaa agcatgtgaa aggaaaaagg 2600

 taaatacagc attgaggctt catttggcct tagtccctgg gagttactgg 2650

 cgttggacag gcttcagtca ttggactaga tgaaaggtgt ccatggttag 2700

 aatttgatct ttgcaaactg tatataattg ttatttttgt ccttaaaaat 2750

 attgtacata cttggttgtt aacatggtca tatttgaaat gtataagtcc 2800

 ataaaataga aaagaacaag tgaattgttg ctatttaaaa aaattttaca 2850

 attcttacta aggagttttt attgtgtaat cactaagtct ttgtagataa 2900

 agcagatggg gagttacgga gttgttcctt tactggctga aagatatatt 2950

 cgaattgtaa agatgctttt tctcatgcat tgaaattata cattatttgt 3000

 agggaattgc atgctttttt ttttttttct cccgagacag ggtcttgctc 3050

 tggcgcccag gctggagtac agtggcatga tcttggctca cttcagcctt 3100

 gacttgggct caagtgatcc tcctacctga gccttctgag taactgggac 3150

 tacaggtgtg cactcctcgc ctggctaatt ttttattttt tgtacaggca 3200

 ggatcttgcc accttgccca ggctggtctt gaactcctga gctcatgcca 3250

 tctgcctgcc ttagtctccc aaaatgctgg gattacagga gtgagccacc 3300

 atgcccggct ggcagttgca tggaagagaa cacctcttta tggcttaccc 3350

 tctagaattt ctaatttatg tgttctgttg aaatttttgt ttttttacct 3400

 ttattgaaac aacaaaaagt cagtattgaa acatatcttc ctgttttctg 3450

 ttgtcaaatg atgataatgt gccatgatgt tttatatata tcattcagaa 3500

 aaagttttat tttttaataa cattctatta acattatttt gcttgccgct 3550

 ggcatgcctg aggaatgtat ttggctttga ttacacacta agtttttgta 3600

 ataaatttga ctcattaaaa accttttttt tttaaaaaaa aaaaaaagaa 3650

 aatctcatta gtgaacttat ctttgcagct gagtacttaa attcttttta 3700

 aaaagatacc ctttggattg atcacattgt ttgacccagt atgtcttgta 3750

 gacacgttag ttataatcac cttgtatctc taaatatggt gtgatatgaa 3800

 ccagtccatt cacattggaa aaactgatgg ttttaaataa actaattcac 3850

 taataaaaaa aaaaaaaaa 3869

<210> 3864
<211> 718
<212> PRT
<213> Homo sapien

<400> 3864
 Met Ile Val Asp Lys Leu Leu Asp Asp Ser Arg Gly Gly Glu Gly
   1               5                  10                  15

 Leu Arg Asp Ala Ala Gly Gly Cys Gly Leu Met Thr Ser Pro Leu
                  20                  25                  30

 Asn Leu Ser Tyr Phe Tyr Gly Ala Ser Pro Pro Ala Ala Ala Pro
                  35                  40                  45

 Gly Ala Cys Asp Ala Ser Cys Ser Val Leu Gly Pro Ser Ala Pro
                  50                  55                  60

 Gly Ser Pro Gly Ser Asp Ser Ser Asp Phe Ser Ser Ala Ser Ser
                  65                  70                  75

 Val Ser Ser Cys Gly Ala Val Glu Ser Arg Ser Arg Gly Gly Ala
                  80                  85                  90

 Arg Ala Glu Arg Gln Pro Val Glu Pro His Met Gly Val Gly Arg
                  95                 100                 105

 Gln Gln Arg Gly Pro Phe Gln Gly Val Arg Val Lys Asn Ser Val
                 110                 115                 120

 Lys Glu Leu Leu Leu His Ile Arg Ser His Lys Gln Lys Ala Ser
                 125                 130                 135

 Gly Gln Ala Val Asp Asp Phe Lys Thr Gln Gly Val Asn Ile Glu
                 140                 145                 150

 Gln Phe Arg Glu Leu Lys Asn Thr Val Ser Tyr Ser Gly Lys Arg
                 155                 160                 165

 Lys Gly Pro Asp Ser Leu Ser Asp Gly Pro Ala Cys Lys Arg Pro
                 170                 175                 180

 Ala Leu Leu His Ser Gln Phe Leu Thr Pro Pro Gln Thr Pro Thr
                 185                 190                 195

 Pro Gly Glu Ser Met Glu Asp Val His Leu Asn Glu Pro Lys Gln
                 200                 205                 210

 Glu Ser Ser Ala Asp Leu Leu Gln Asn Ile Ile Asn Ile Lys Asn
                 215                 220                 225

 Glu Cys Ser Pro Val Ser Leu Asn Thr Val Gln Val Ser Trp Leu
                 230                 235                 240

 Asn Pro Val Val Val Pro Gln Ser Ser Pro Ala Glu Gln Cys Gln
                 245                 250                 255

 Asp Phe His Gly Gly Gln Val Phe Ser Pro Pro Gln Lys Cys Gln
                 260                 265                 270

 Pro Phe Gln Val Arg Gly Ser Gln Gln Met Ile Asp Gln Ala Ser
                 275                 280                 285

 Leu Tyr Gln Tyr Ser Pro Gln Asn Gln His Val Glu Gln Gln Pro
                 290                 295                 300

 His Tyr Thr His Lys Pro Thr Leu Glu Tyr Ser Pro Phe Pro Ile
                 305                 310                 315

 Pro Pro Gln Ser Pro Ala Tyr Glu Pro Asn Leu Phe Asp Gly Pro
                 320                 325                 330

 Glu Ser Gln Phe Cys Pro Asn Gln Ser Leu Val Ser Leu Leu Gly
                 335                 340                 345

 Asp Gln Arg Glu Ser Glu Asn Ile Ala Asn Pro Met Gln Thr Ser
                 350                 355                 360

 Ser Ser Val Gln Gln Gln Asn Asp Ala His Leu His Ser Phe Ser
                 365                 370                 375

 Met Met Pro Ser Ser Ala Cys Glu Ala Met Val Gly His Glu Met
                 380                 385                 390

 Ala Ser Asp Ser Ser Asn Thr Ser Leu Pro Phe Ser Asn Met Gly
                 395                 400                 405

 Asn Pro Met Asn Thr Thr Gln Leu Gly Lys Ser Leu Phe Gln Trp
                 410                 415                 420

 Gln Val Glu Gln Glu Glu Ser Lys Leu Ala Asn Ile Ser Gln Asp
                 425                 430                 435

 Gln Phe Leu Ser Lys Asp Ala Asp Gly Asp Thr Phe Leu His Ile
                 440                 445                 450

 Ala Val Ala Gln Gly Arg Arg Ala Leu Ser Tyr Val Leu Ala Arg
                 455                 460                 465

 Lys Met Asn Ala Leu His Met Leu Asp Ile Lys Glu His Asn Gly
                 470                 475                 480

 Gln Ser Ala Phe Gln Val Ala Val Ala Ala Asn Gln His Leu Ile
                 485                 490                 495

 Val Gln Asp Leu Val Asn Ile Gly Ala Gln Val Asn Thr Thr Asp
                 500                 505                 510

 Cys Trp Gly Arg Thr Pro Leu His Val Cys Ala Glu Lys Gly His
                 515                 520                 525

 Ser Gln Val Leu Gln Ala Ile Gln Lys Gly Ala Val Gly Ser Asn
                 530                 535                 540

 Gln Phe Val Asp Leu Glu Ala Thr Asn Tyr Asp Gly Leu Thr Pro
                 545                 550                 555

 Leu His Cys Ala Val Ile Ala His Asn Ala Val Val His Glu Leu
                 560                 565                 570

 Gln Arg Asn Gln Gln Pro His Ser Pro Glu Val Gln Glu Leu Leu
                 575                 580                 585

 Leu Lys Asn Lys Ser Leu Val Asp Thr Ile Lys Cys Leu Ile Gln
                 590                 595                 600

 Met Gly Ala Ala Val Glu Ala Lys Asp Arg Lys Ser Gly Arg Thr
                 605                 610                 615

 Ala Leu His Leu Ala Ala Glu Glu Ala Asn Leu Glu Leu Ile Arg
                 620                 625                 630

 Leu Phe Leu Glu Leu Pro Ser Cys Leu Ser Phe Val Asn Ala Lys
                 635                 640                 645

 Ala Tyr Asn Gly Asn Thr Ala Leu His Val Ala Ala Ser Leu Gln
                 650                 655                 660

 Tyr Arg Leu Thr Gln Leu Asp Ala Val Arg Leu Leu Met Arg Lys
                 665                 670                 675

 Gly Ala Asp Pro Ser Thr Arg Asn Leu Glu Asn Glu Gln Pro Val
                 680                 685                 690

 His Leu Val Pro Asp Gly Pro Val Gly Glu Gln Ile Arg Arg Ile
                 695                 700                 705

 Leu Lys Gly Lys Ser Ile Gln Gln Arg Ala Pro Pro Tyr
                 710                 715

<210> 3865
<211> 3869
<212> DNA
<213> Homo sapien

<400> 3865
 gagccggtgg cgcaggtgtc ggggtcctcg agcgcccagc ctgggagcat 50

 gattgtggac aagctgctgg acgacagccg cggcggagag gggctgcggg 100

 acgcggcggg cggctgcggc ctcatgacca gcccgctcaa cctgagctac 150

 ttctacggcg cgtcgccgcc cgccgccgcc ccgggcgcct gcgacgccag 200

 ctgctcggtc ttgggcccct cggcgcccgg ctcgcccggc tccgactcct 250

 ccgacttctc ctctgcctcg tcggtgtcct cctgcggcgc cgtggagtcc 300

 cggtcgagag gcggcgcccg cgccgagcgc cagccagttg agccccatat 350

 gggggttggc aggcagcaga gaggcccctt tcaaggtgtt cgggtaaaga 400

 actcagtgaa ggaactcctg ttgcacatcc gaagtcataa acagaaggct 450

 tctggccaag ctgtggatga ttttaagaca caaggtgtga acatagaaca 500

 gttcagagaa ttgaagaaca cagtatcata cagtgggaaa aggaaagggc 550

 ccgattcgtt gtctgatgga cctgcttgca aaaggccagc tctgttgcat 600

 tcccaatttt tgacaccacc tcaaacacca acgcccgggg agagcatgga 650

 agatgttcat ctcaatgaac ccaaacagga gagcagtgct gatctgcttc 700

 agaacattat caacattaag aatgaatgca gccccgtttc cctgaacaca 750

 gttcaagtta gctggctgaa ccccgtggtg gtccctcaga gctcccccgc 800

 agagcagtgt caggacttcc atggagggca ggtcttttct ccacctcaga 850

 aatgccaacc attccaagtc aggggctccc aacaaatgat agaccaggct 900

 tccctgtacc agtattctcc acagaaccag catgtagagc agcagccaca 950

 ctacacccac aaaccaactc tggaatacag tccttttccc atacctcccc 1000

 agtcccccgc ttatgaacca aacctctttg atggtccaga atcacagttt 1050

 tgcccaaacc aaagcttagt ttcccttctt ggtgatcaaa gggaatctga 1100

 gaatattgct aatcccatgc agacttcctc cagtgttcag cagcaaaatg 1150

 atgctcactt gcacagcttc agcatgatgc ccagcagcgc ctgtgaggcc 1200

 atggtggggc acgagatggc ctctgactct tcaaacactt cactgccatt 1250

 ctcaaacatg ggaaatccaa tgaacaccac acagttaggg aaatcacttt 1300

 ttcagtggca ggtggagcag gaagaaagca aattggcaaa tatttcccaa 1350

 gaccagtttc tttcaaagga tgcagatggt gacacgttcc ttcatattgc 1400

 tgttgcccaa gggagaaggg cactttccta tgttcttgca agaaagatga 1450

 atgcacttca catgctggat attaaagagc acaatggaca gagtgccttt 1500

 caggtggcag tggctgccaa tcagcatctc attgtgcagg atctggtgaa 1550

 catcggggca caggtgaaca ccacagactg ctggggaaga acacctctgc 1600

 atgtgtgtgc tgagaagggc cactcccagg tgcttcaggc gattcagaag 1650

 ggagcagtgg gaagtaatca gtttgtggat cttgaggcaa ctaactatga 1700

 tggcctgact ccccttcact gtgcagtcat agcccacaat gctgtggtcc 1750

 atgaactcca gagaaatcaa cagcctcatt cacctgaagt tcaggagctt 1800

 ttactgaaga ataagagtct ggttgatacc attaagtgcc taattcaaat 1850

 gggagcagcg gtggaagcga aggatcgcaa aagtggccgc acagccctgc 1900

 atttggcagc tgaagaagca aatctggaac tcattcgcct ctttttggag 1950

 ctgcccagtt gcctgtcttt tgtgaatgca aaggcttaca atggcaacac 2000

 tgccctccat gttgctgcca gcttgcagta tcggttgaca caattagatg 2050

 ctgtccgcct gttgatgagg aagggagcag acccaagtac tcggaacttg 2100

 gagaacgaac agccagtgca tttggttccc gatggccctg tgggagaaca 2150

 gatccgacgt atcctgaagg gaaagtccat tcagcagaga gctccaccgt 2200

 attagctcca ttagcttgga gcctggctag caacactcac tgtcagttag 2250

 gcagtcctga tgtatctgta catagaccat ttgccttata ttggcaaatg 2300

 taagttgttt ctatgaaaca aacatattta gttcactatt atatagtggg 2350

 ttatattaaa agaaaagaag aaaaatatct aatttctctt ggcagatttg 2400

 catatttcat acccaggtat ctgggatcta gacatctgaa tttgatctca 2450

 atggtaacat tgccttcaat taacagtagc ttttgagtag gaaaggactt 2500

 tgatttgtgg cacaaaacat tattaatata gctattgaca gtttcaaagc 2550

 aggtaaattg taaatgtttc tttaagaaaa agcatgtgaa aggaaaaagg 2600

 taaatacagc attgaggctt catttggcct tagtccctgg gagttactgg 2650

 cgttggacag gcttcagtca ttggactaga tgaaaggtgt ccatggttag 2700

 aatttgatct ttgcaaactg tatataattg ttatttttgt ccttaaaaat 2750

 attgtacata cttggttgtt aacatggtca tatttgaaat gtataagtcc 2800

 ataaaataga aaagaacaag tgaattgttg ctatttaaaa aaattttaca 2850

 attcttacta aggagttttt attgtgtaat cactaagtct ttgtagataa 2900

 agcagatggg gagttacgga gttgttcctt tactggctga aagatatatt 2950

 cgaattgtaa agatgctttt tctcatgcat tgaaattata cattatttgt 3000

 agggaattgc atgctttttt ttttttttct cccgagacag ggtcttgctc 3050

 tggcgcccag gctggagtac agtggcatga tcttggctca cttcagcctt 3100

 gacttgggct caagtgatcc tcctacctga gccttctgag taactgggac 3150

 tacaggtgtg cactcctcgc ctggctaatt ttttattttt tgtacaggca 3200

 ggatcttgcc accttgccca ggctggtctt gaactcctga gctcatgcca 3250

 tctgcctgcc ttagtctccc aaaatgctgg gattacagga gtgagccacc 3300

 atgcccggct ggcagttgca tggaagagaa cacctcttta tggcttaccc 3350

 tctagaattt ctaatttatg tgttctgttg aaatttttgt ttttttacct 3400

 ttattgaaac aacaaaaagt cagtattgaa acatatcttc ctgttttctg 3450

 ttgtcaaatg atgataatgt gccatgatgt tttatatata tcattcagaa 3500

 aaagttttat tttttaataa cattctatta acattatttt gcttgccgct 3550

 ggcatgcctg aggaatgtat ttggctttga ttacacacta agtttttgta 3600

 ataaatttga ctcattaaaa accttttttt tttaaaaaaa aaaaaaagaa 3650

 aatctcatta gtgaacttat ctttgcagct gagtacttaa attcttttta 3700

 aaaagatacc ctttggattg atcacattgt ttgacccagt atgtcttgta 3750

 gacacgttag ttataatcac cttgtatctc taaatatggt gtgatatgaa 3800

 ccagtccatt cacattggaa aaactgatgg ttttaaataa actaattcac 3850

 taataaaaaa aaaaaaaaa 3869

<210> 3866
<211> 718
<212> PRT
<213> Homo sapien

<400> 3866
 Met Ile Val Asp Lys Leu Leu Asp Asp Ser Arg Gly Gly Glu Gly
   1               5                  10                  15

 Leu Arg Asp Ala Ala Gly Gly Cys Gly Leu Met Thr Ser Pro Leu
                  20                  25                  30

 Asn Leu Ser Tyr Phe Tyr Gly Ala Ser Pro Pro Ala Ala Ala Pro
                  35                  40                  45

 Gly Ala Cys Asp Ala Ser Cys Ser Val Leu Gly Pro Ser Ala Pro
                  50                  55                  60

 Gly Ser Pro Gly Ser Asp Ser Ser Asp Phe Ser Ser Ala Ser Ser
                  65                  70                  75

 Val Ser Ser Cys Gly Ala Val Glu Ser Arg Ser Arg Gly Gly Ala
                  80                  85                  90

 Arg Ala Glu Arg Gln Pro Val Glu Pro His Met Gly Val Gly Arg
                  95                 100                 105

 Gln Gln Arg Gly Pro Phe Gln Gly Val Arg Val Lys Asn Ser Val
                 110                 115                 120

 Lys Glu Leu Leu Leu His Ile Arg Ser His Lys Gln Lys Ala Ser
                 125                 130                 135

 Gly Gln Ala Val Asp Asp Phe Lys Thr Gln Gly Val Asn Ile Glu
                 140                 145                 150

 Gln Phe Arg Glu Leu Lys Asn Thr Val Ser Tyr Ser Gly Lys Arg
                 155                 160                 165

 Lys Gly Pro Asp Ser Leu Ser Asp Gly Pro Ala Cys Lys Arg Pro
                 170                 175                 180

 Ala Leu Leu His Ser Gln Phe Leu Thr Pro Pro Gln Thr Pro Thr
                 185                 190                 195

 Pro Gly Glu Ser Met Glu Asp Val His Leu Asn Glu Pro Lys Gln
                 200                 205                 210

 Glu Ser Ser Ala Asp Leu Leu Gln Asn Ile Ile Asn Ile Lys Asn
                 215                 220                 225

 Glu Cys Ser Pro Val Ser Leu Asn Thr Val Gln Val Ser Trp Leu
                 230                 235                 240

 Asn Pro Val Val Val Pro Gln Ser Ser Pro Ala Glu Gln Cys Gln
                 245                 250                 255

 Asp Phe His Gly Gly Gln Val Phe Ser Pro Pro Gln Lys Cys Gln
                 260                 265                 270

 Pro Phe Gln Val Arg Gly Ser Gln Gln Met Ile Asp Gln Ala Ser
                 275                 280                 285

 Leu Tyr Gln Tyr Ser Pro Gln Asn Gln His Val Glu Gln Gln Pro
                 290                 295                 300

 His Tyr Thr His Lys Pro Thr Leu Glu Tyr Ser Pro Phe Pro Ile
                 305                 310                 315

 Pro Pro Gln Ser Pro Ala Tyr Glu Pro Asn Leu Phe Asp Gly Pro
                 320                 325                 330

 Glu Ser Gln Phe Cys Pro Asn Gln Ser Leu Val Ser Leu Leu Gly
                 335                 340                 345

 Asp Gln Arg Glu Ser Glu Asn Ile Ala Asn Pro Met Gln Thr Ser
                 350                 355                 360

 Ser Ser Val Gln Gln Gln Asn Asp Ala His Leu His Ser Phe Ser
                 365                 370                 375

 Met Met Pro Ser Ser Ala Cys Glu Ala Met Val Gly His Glu Met
                 380                 385                 390

 Ala Ser Asp Ser Ser Asn Thr Ser Leu Pro Phe Ser Asn Met Gly
                 395                 400                 405

 Asn Pro Met Asn Thr Thr Gln Leu Gly Lys Ser Leu Phe Gln Trp
                 410                 415                 420

 Gln Val Glu Gln Glu Glu Ser Lys Leu Ala Asn Ile Ser Gln Asp
                 425                 430                 435

 Gln Phe Leu Ser Lys Asp Ala Asp Gly Asp Thr Phe Leu His Ile
                 440                 445                 450

 Ala Val Ala Gln Gly Arg Arg Ala Leu Ser Tyr Val Leu Ala Arg
                 455                 460                 465

 Lys Met Asn Ala Leu His Met Leu Asp Ile Lys Glu His Asn Gly
                 470                 475                 480

 Gln Ser Ala Phe Gln Val Ala Val Ala Ala Asn Gln His Leu Ile
                 485                 490                 495

 Val Gln Asp Leu Val Asn Ile Gly Ala Gln Val Asn Thr Thr Asp
                 500                 505                 510

 Cys Trp Gly Arg Thr Pro Leu His Val Cys Ala Glu Lys Gly His
                 515                 520                 525

 Ser Gln Val Leu Gln Ala Ile Gln Lys Gly Ala Val Gly Ser Asn
                 530                 535                 540

 Gln Phe Val Asp Leu Glu Ala Thr Asn Tyr Asp Gly Leu Thr Pro
                 545                 550                 555

 Leu His Cys Ala Val Ile Ala His Asn Ala Val Val His Glu Leu
                 560                 565                 570

 Gln Arg Asn Gln Gln Pro His Ser Pro Glu Val Gln Glu Leu Leu
                 575                 580                 585

 Leu Lys Asn Lys Ser Leu Val Asp Thr Ile Lys Cys Leu Ile Gln
                 590                 595                 600

 Met Gly Ala Ala Val Glu Ala Lys Asp Arg Lys Ser Gly Arg Thr
                 605                 610                 615

 Ala Leu His Leu Ala Ala Glu Glu Ala Asn Leu Glu Leu Ile Arg
                 620                 625                 630

 Leu Phe Leu Glu Leu Pro Ser Cys Leu Ser Phe Val Asn Ala Lys
                 635                 640                 645

 Ala Tyr Asn Gly Asn Thr Ala Leu His Val Ala Ala Ser Leu Gln
                 650                 655                 660

 Tyr Arg Leu Thr Gln Leu Asp Ala Val Arg Leu Leu Met Arg Lys
                 665                 670                 675

 Gly Ala Asp Pro Ser Thr Arg Asn Leu Glu Asn Glu Gln Pro Val
                 680                 685                 690

 His Leu Val Pro Asp Gly Pro Val Gly Glu Gln Ile Arg Arg Ile
                 695                 700                 705

 Leu Lys Gly Lys Ser Ile Gln Gln Arg Ala Pro Pro Tyr
                 710                 715

<210> 3867
<211> 3243
<212> DNA
<213> Homo sapien

<400> 3867
 gggcttcgtg ttcctgggtg ctgaccgtgc actccccgcc gcccgaggac 50

 ttagagctct ggaagtagct ctccagcttc cttcgtactc gggggccgga 100

 cttgtacacc cgcacgagga gcggggacgg cgggcgcaga agtgggccac 150

 catatctgga aactacagtc tatgctttga agcgcaaaag ggaataaaca 200

 tttaaagact cccccgggga cctggaggat ggacttttcc atggtggccg 250

 gagcagcagc ttacaatgaa aaatcaggta ggattacctc gctctcactc 300

 ttgtttcaga aagtctttgc tcagatcttt cctcagtgga gaaaggggaa 350

 tacagaagaa tgtctcccct acaagtgctc agagactggt gctcttggag 400

 aaaactatag ttggcaaatt cccattaacc acaatgactt caaaatttta 450

 aaaaataatg agcgtcagct gtgtgaagtc ctccagaata agtttggctg 500

 tatctctacc ctggtctctc cagttcagga aggcaacagc aaatctctgc 550

 aagtgttcag aaaaatgctg actcctagga tagagttatc agtctggaaa 600

 gatgacctca ccacacatgc tgttgatgct gtggtgaatg cagccaatga 650

 agatcttctg catgggggag gcctggccct ggccctggta aaagctggtg 700

 gatttgaaat ccaagaagag agcaaacagt ttgttgccag atatggtaaa 750

 gtgtcagctg gtgagatagc tgtcacggga gcagggaggc ttccctgcaa 800

 acagatcatc catgctgttg ggcctcggtg gatggaatgg gataaacagg 850

 gatgtactgg aaagctgcag agggccattg taagtattct gaattatgtc 900

 atctataaaa atactcacat taagacagta gcaattccag ccttgagctc 950

 tgggattttt cagttccctc tgaatttgtg tacaaagact attgtagaga 1000

 ctatccgggt tagtttgcaa gggaagccaa tgatgagtaa tttgaaagaa 1050

 attcacctgg tgagcaatga ggaccctact gttgctgcct ttaaagctgc 1100

 ttcagaattc atcctaggga agagtgagct gggacaagaa accacccctt 1150

 ctttcaatgc aatggtcgtg aacaacctga ccctccagat tgtccagggc 1200

 cacattgaat ggcagacggc agatgtaatt gttaattctg taaacccaca 1250

 tgatattaca gttggacctg tggcaaagtc aattctacaa caagcaggag 1300

 ttgaaatgaa atcggaattt cttgccacaa aggctaaaca gtttcaacgg 1350

 tcccagttgg tactggtcac aaaaggattt aacttgttct gtaaatatat 1400

 ataccatgta ctgtggcatt cagaatttcc taaacctcag atattaaaac 1450

 atgcaatgaa ggagtgtttg gaaaaatgca ttgagcaaaa tataacttcc 1500

 atttcctttc ctgcccttgg gactggaaac atggaaataa agaaggaaac 1550

 agcagcagag attttgtttg atgaagtttt aacatttgcc aaagaccatg 1600

 taaaacacca gttaactgta aaatttgtga tctttccaac agatttggag 1650

 atatataagg ctttcagttc tgaaatggca aagaggtcca agatgctgag 1700

 tttgaacaat tacagtgtcc cccagtcaac cagagaggag aaaagagaaa 1750

 atgggcttga agctagatct cctgccatca atctgatggg attcaacgtg 1800

 gaagagatgt gtgaggccca cgcatggatc caaagaatcc tgagtctcca 1850

 gaaccaccac atcattgaga ataatcatat tctgtacctt gggagaaagg 1900

 aacatgacat tttgtctcag cttcagaaaa cttcaagtgt ctccatcaca 1950

 gaaattatca gcccaggaag gacagagtta gagattgaag gagcccgggc 2000

 tgacctcatt gaggtggtta tgaacattga agatatgctt tgtaaagtac 2050

 aggaggaaat ggcaaggaaa aaggagcgag gcctttggcg ctcgttagga 2100

 cagtggacta ttcagcaaca aaaaacccaa gacgaaatga aagaaaatat 2150

 catatttctg aaatgtcctg tgcctccaac tcaagagctt ctagatcaaa 2200

 agaaacagtt tgaaaaatgt ggtttgcagg ttctaaaggt ggagaagata 2250

 gacaatgagg tccttatggc tgcctttcaa agaaagaaga aaatgatgga 2300

 agaaaaactg cacaggcaac ctgtgagcca taggctgttt cagcaagtcc 2350

 cataccagtt ctgcaatgtg gtatgcagag ttggctttca aagaatgtac 2400

 tcgacacctt gcgatccaaa atacggagct ggcatatact tcaccaagaa 2450

 cctcaaaaac ctggcagaga aggccaagaa aatctctgct gcagataagc 2500

 tgatctatgt gtttgaggct gaagtactca caggcttctt ctgccaggga 2550

 catccgttaa atattgttcc cccaccactg agtcctggag ctatagatgg 2600

 tcatgacagt gtggttgaca atgtctccag ccctgaaacc tttgttattt 2650

 ttagtggcat gcaggctata cctcagtatt tgtggacatg cacccaggaa 2700

 tatgtacagt cacaagatta ctcatcagga ccaatgagac cctttgcaca 2750

 gcatccttgg aggggattcg caagtggcag ccctgttgat taatctctac 2800

 atcattttaa cagctggtat ggccttacct tgggtgaact aaccaaataa 2850

 tgaccatcga tggctcaaag agtggcttga atatatccca tgggttatct 2900

 gtatggactg actgggttat tgaaaggact agccacatac tagcatctta 2950

 gtgcctttat ctgtctttat gtcttggggt tggggtaggt agataccaaa 3000

 tgaaacactt tcaggacctt ccttcctctt gcagttgttc tttaatctcc 3050

 tttactagag gagataaata ttttgcatat aatgaagaaa tttttctagt 3100

 atataacgca ggccttttat tttctaaaat gatgatagta taaaaatgtt 3150

 aggataacag aatgatttta gattttccag agaatattat aaagtgcttt 3200

 aggtatgaaa ataaatcatc tttgtctgat taaaaaaaaa aaa 3243

<210> 3868
<211> 854
<212> PRT
<213> Homo sapien

<400> 3868
 Met Asp Phe Ser Met Val Ala Gly Ala Ala Ala Tyr Asn Glu Lys
   1               5                  10                  15

 Ser Gly Arg Ile Thr Ser Leu Ser Leu Leu Phe Gln Lys Val Phe
                  20                  25                  30

 Ala Gln Ile Phe Pro Gln Trp Arg Lys Gly Asn Thr Glu Glu Cys
                  35                  40                  45

 Leu Pro Tyr Lys Cys Ser Glu Thr Gly Ala Leu Gly Glu Asn Tyr
                  50                  55                  60

 Ser Trp Gln Ile Pro Ile Asn His Asn Asp Phe Lys Ile Leu Lys
                  65                  70                  75

 Asn Asn Glu Arg Gln Leu Cys Glu Val Leu Gln Asn Lys Phe Gly
                  80                  85                  90

 Cys Ile Ser Thr Leu Val Ser Pro Val Gln Glu Gly Asn Ser Lys
                  95                 100                 105

 Ser Leu Gln Val Phe Arg Lys Met Leu Thr Pro Arg Ile Glu Leu
                 110                 115                 120

 Ser Val Trp Lys Asp Asp Leu Thr Thr His Ala Val Asp Ala Val
                 125                 130                 135

 Val Asn Ala Ala Asn Glu Asp Leu Leu His Gly Gly Gly Leu Ala
                 140                 145                 150

 Leu Ala Leu Val Lys Ala Gly Gly Phe Glu Ile Gln Glu Glu Ser
                 155                 160                 165

 Lys Gln Phe Val Ala Arg Tyr Gly Lys Val Ser Ala Gly Glu Ile
                 170                 175                 180

 Ala Val Thr Gly Ala Gly Arg Leu Pro Cys Lys Gln Ile Ile His
                 185                 190                 195

 Ala Val Gly Pro Arg Trp Met Glu Trp Asp Lys Gln Gly Cys Thr
                 200                 205                 210

 Gly Lys Leu Gln Arg Ala Ile Val Ser Ile Leu Asn Tyr Val Ile
                 215                 220                 225

 Tyr Lys Asn Thr His Ile Lys Thr Val Ala Ile Pro Ala Leu Ser
                 230                 235                 240

 Ser Gly Ile Phe Gln Phe Pro Leu Asn Leu Cys Thr Lys Thr Ile
                 245                 250                 255

 Val Glu Thr Ile Arg Val Ser Leu Gln Gly Lys Pro Met Met Ser
                 260                 265                 270

 Asn Leu Lys Glu Ile His Leu Val Ser Asn Glu Asp Pro Thr Val
                 275                 280                 285

 Ala Ala Phe Lys Ala Ala Ser Glu Phe Ile Leu Gly Lys Ser Glu
                 290                 295                 300

 Leu Gly Gln Glu Thr Thr Pro Ser Phe Asn Ala Met Val Val Asn
                 305                 310                 315

 Asn Leu Thr Leu Gln Ile Val Gln Gly His Ile Glu Trp Gln Thr
                 320                 325                 330

 Ala Asp Val Ile Val Asn Ser Val Asn Pro His Asp Ile Thr Val
                 335                 340                 345

 Gly Pro Val Ala Lys Ser Ile Leu Gln Gln Ala Gly Val Glu Met
                 350                 355                 360

 Lys Ser Glu Phe Leu Ala Thr Lys Ala Lys Gln Phe Gln Arg Ser
                 365                 370                 375

 Gln Leu Val Leu Val Thr Lys Gly Phe Asn Leu Phe Cys Lys Tyr
                 380                 385                 390

 Ile Tyr His Val Leu Trp His Ser Glu Phe Pro Lys Pro Gln Ile
                 395                 400                 405

 Leu Lys His Ala Met Lys Glu Cys Leu Glu Lys Cys Ile Glu Gln
                 410                 415                 420

 Asn Ile Thr Ser Ile Ser Phe Pro Ala Leu Gly Thr Gly Asn Met
                 425                 430                 435

 Glu Ile Lys Lys Glu Thr Ala Ala Glu Ile Leu Phe Asp Glu Val
                 440                 445                 450

 Leu Thr Phe Ala Lys Asp His Val Lys His Gln Leu Thr Val Lys
                 455                 460                 465

 Phe Val Ile Phe Pro Thr Asp Leu Glu Ile Tyr Lys Ala Phe Ser
                 470                 475                 480

 Ser Glu Met Ala Lys Arg Ser Lys Met Leu Ser Leu Asn Asn Tyr
                 485                 490                 495

 Ser Val Pro Gln Ser Thr Arg Glu Glu Lys Arg Glu Asn Gly Leu
                 500                 505                 510

 Glu Ala Arg Ser Pro Ala Ile Asn Leu Met Gly Phe Asn Val Glu
                 515                 520                 525

 Glu Met Cys Glu Ala His Ala Trp Ile Gln Arg Ile Leu Ser Leu
                 530                 535                 540

 Gln Asn His His Ile Ile Glu Asn Asn His Ile Leu Tyr Leu Gly
                 545                 550                 555

 Arg Lys Glu His Asp Ile Leu Ser Gln Leu Gln Lys Thr Ser Ser
                 560                 565                 570

 Val Ser Ile Thr Glu Ile Ile Ser Pro Gly Arg Thr Glu Leu Glu
                 575                 580                 585

 Ile Glu Gly Ala Arg Ala Asp Leu Ile Glu Val Val Met Asn Ile
                 590                 595                 600

 Glu Asp Met Leu Cys Lys Val Gln Glu Glu Met Ala Arg Lys Lys
                 605                 610                 615

 Glu Arg Gly Leu Trp Arg Ser Leu Gly Gln Trp Thr Ile Gln Gln
                 620                 625                 630

 Gln Lys Thr Gln Asp Glu Met Lys Glu Asn Ile Ile Phe Leu Lys
                 635                 640                 645

 Cys Pro Val Pro Pro Thr Gln Glu Leu Leu Asp Gln Lys Lys Gln
                 650                 655                 660

 Phe Glu Lys Cys Gly Leu Gln Val Leu Lys Val Glu Lys Ile Asp
                 665                 670                 675

 Asn Glu Val Leu Met Ala Ala Phe Gln Arg Lys Lys Lys Met Met
                 680                 685                 690

 Glu Glu Lys Leu His Arg Gln Pro Val Ser His Arg Leu Phe Gln
                 695                 700                 705

 Gln Val Pro Tyr Gln Phe Cys Asn Val Val Cys Arg Val Gly Phe
                 710                 715                 720

 Gln Arg Met Tyr Ser Thr Pro Cys Asp Pro Lys Tyr Gly Ala Gly
                 725                 730                 735

 Ile Tyr Phe Thr Lys Asn Leu Lys Asn Leu Ala Glu Lys Ala Lys
                 740                 745                 750

 Lys Ile Ser Ala Ala Asp Lys Leu Ile Tyr Val Phe Glu Ala Glu
                 755                 760                 765

 Val Leu Thr Gly Phe Phe Cys Gln Gly His Pro Leu Asn Ile Val
                 770                 775                 780

 Pro Pro Pro Leu Ser Pro Gly Ala Ile Asp Gly His Asp Ser Val
                 785                 790                 795

 Val Asp Asn Val Ser Ser Pro Glu Thr Phe Val Ile Phe Ser Gly
                 800                 805                 810

 Met Gln Ala Ile Pro Gln Tyr Leu Trp Thr Cys Thr Gln Glu Tyr
                 815                 820                 825

 Val Gln Ser Gln Asp Tyr Ser Ser Gly Pro Met Arg Pro Phe Ala
                 830                 835                 840

 Gln His Pro Trp Arg Gly Phe Ala Ser Gly Ser Pro Val Asp
                 845                 850

<210> 3869
<211> 1580
<212> DNA
<213> Homo sapien

<400> 3869
 ccgggccgca cccgccgagc cgtgaaaaaa agtacatctc ctggaaggga 50

 tgctttttag ctgagctctg gtggatgaga ggagctagcc ttgaaaaact 100

 tgatactgat ggacattgtg tgggccagag gcagggatgg ttggctatga 150

 ccccaaacca gatggcagga ataacaccaa gttccaggtg gcagtggctg 200

 ggtctgtgtc tggacttgtt actcgggcgc tgatcagtcc cttcgacgtc 250

 atcaagatcc gtttccagct tcagcatgag cgcctgtctc gcagtgaccc 300

 cagcgcaaag taccatggca tcctccaggc ctctaggcag attctgcagg 350

 aggagggtcc gacagctttc tggaaaggac acgtcccagc tcagattctc 400

 tccataggct atggagctgt ccaattcttg tcatttgaaa tgctgacgga 450

 gctggtccac agaggcagcg tgtacgacgc ccgggaattc tcagtgcact 500

 ttgtatgtgg tggcctggct gcctgtatgg ccaccctcac tgtgcacccc 550

 gtggatgttc tgcgcacccg ctttgcagct cagggtgagc ccaaggtcta 600

 taatacgctg cgccacgccg tggggaccat gtataggagc gaaggccccc 650

 aggttttcta caaaggcttg gctcccacct tgatcgccat cttcccctac 700

 gccgggctgc agttctcttg ctacagctcc ttgaagcacc tgtacaagtg 750

 ggccatacca gccgaaggaa agaaaaatga gaacctccaa aacctgcttt 800

 gtggcagtgg agctggtgtc atcagcaaga ccctgacata tccgctggac 850

 ctcttcaaga agcggctaca ggttggaggg tttgagcatg ccagagctgc 900

 ctttggccag gtacggagat acaagggcct catggactgt gccaagcagg 950

 tgctacaaaa ggaaggcgcc ctgggcttct tcaagggcct gtcccccagc 1000

 ttgctgaagg ctgccctctc cacaggcttc atgttcttct cgtatgaatt 1050

 cttctgtaat gtcttccact gcatgaacag gacagccagc cagcgctgag 1100

 cgcaggaagg accccaggtc ttccctggag gcagcctcct gaaggaagga 1150

 agattcagtc tccactgaga ggtgccgtct ggcccttccc tgcaggccag 1200

 ctgccccaag cggggtagca gccttgaacc cacccagctg ggacaccacc 1250

 agaaggtcca gggctctccc catgagagaa tcagagggaa tgcaggacgt 1300

 ggtctatggt gagccaacga cacagtgaga aggagcagga agttgctgtt 1350

 tctcctctga ccagcccaca ctgcaaagga aacagacgcc atcctacacc 1400

 tatcagccct gcctgccagg agaacagaac acactcctgg tctggatggg 1450

 gctgctgctt gagtgcagag ggctgcggta ggccctttgc aggagtcagg 1500

 tccctacact tggcctgttt ttccaaccta tttaatagac attaaagcta 1550

 aacacacaaa aaaaaaaaaa aaaaaaaaaa 1580

<210> 3870
<211> 320
<212> PRT
<213> Homo sapien

<400> 3870
 Met Val Gly Tyr Asp Pro Lys Pro Asp Gly Arg Asn Asn Thr Lys
   1               5                  10                  15

 Phe Gln Val Ala Val Ala Gly Ser Val Ser Gly Leu Val Thr Arg
                  20                  25                  30

 Ala Leu Ile Ser Pro Phe Asp Val Ile Lys Ile Arg Phe Gln Leu
                  35                  40                  45

 Gln His Glu Arg Leu Ser Arg Ser Asp Pro Ser Ala Lys Tyr His
                  50                  55                  60

 Gly Ile Leu Gln Ala Ser Arg Gln Ile Leu Gln Glu Glu Gly Pro
                  65                  70                  75

 Thr Ala Phe Trp Lys Gly His Val Pro Ala Gln Ile Leu Ser Ile
                  80                  85                  90

 Gly Tyr Gly Ala Val Gln Phe Leu Ser Phe Glu Met Leu Thr Glu
                  95                 100                 105

 Leu Val His Arg Gly Ser Val Tyr Asp Ala Arg Glu Phe Ser Val
                 110                 115                 120

 His Phe Val Cys Gly Gly Leu Ala Ala Cys Met Ala Thr Leu Thr
                 125                 130                 135

 Val His Pro Val Asp Val Leu Arg Thr Arg Phe Ala Ala Gln Gly
                 140                 145                 150

 Glu Pro Lys Val Tyr Asn Thr Leu Arg His Ala Val Gly Thr Met
                 155                 160                 165

 Tyr Arg Ser Glu Gly Pro Gln Val Phe Tyr Lys Gly Leu Ala Pro
                 170                 175                 180

 Thr Leu Ile Ala Ile Phe Pro Tyr Ala Gly Leu Gln Phe Ser Cys
                 185                 190                 195

 Tyr Ser Ser Leu Lys His Leu Tyr Lys Trp Ala Ile Pro Ala Glu
                 200                 205                 210

 Gly Lys Lys Asn Glu Asn Leu Gln Asn Leu Leu Cys Gly Ser Gly
                 215                 220                 225

 Ala Gly Val Ile Ser Lys Thr Leu Thr Tyr Pro Leu Asp Leu Phe
                 230                 235                 240

 Lys Lys Arg Leu Gln Val Gly Gly Phe Glu His Ala Arg Ala Ala
                 245                 250                 255

 Phe Gly Gln Val Arg Arg Tyr Lys Gly Leu Met Asp Cys Ala Lys
                 260                 265                 270

 Gln Val Leu Gln Lys Glu Gly Ala Leu Gly Phe Phe Lys Gly Leu
                 275                 280                 285

 Ser Pro Ser Leu Leu Lys Ala Ala Leu Ser Thr Gly Phe Met Phe
                 290                 295                 300

 Phe Ser Tyr Glu Phe Phe Cys Asn Val Phe His Cys Met Asn Arg
                 305                 310                 315

 Thr Ala Ser Gln Arg
                 320

<210> 3871
<211> 2978
<212> DNA
<213> Homo sapien

<400> 3871
 tgtcaagttt gcagggtgca gcttggatgt ggtgctagaa ggggaagcct 50

 ctgggctgag catgtaggct cgtcagtaga gttcaacccg caggagtaaa 100

 ttactgcagt gggaaacaac cgcacccgcg gcccagcagg ggttccactg 150

 cgcagccgca aaaggcgccg aggctccacc gcgcagccac agaaggcgcc 200

 gaggctccac cgcgcagccg caaaaagagc ggacgggtct gcgccgccgc 250

 aggaggagca ggcggtacct ggacgggttc gtcccgggct gtttcgcgtc 300

 cggcctgagg cggctggggc cgcgcaggta gtgtccctgc acttcttgcc 350

 cgggcgcgtg aggccagctc cgctgcgctt gtctccagct tccagccctc 400

 ctcccctaag ccgccgccat catgctgctg cctgtgttca ccctgaaact 450

 gcgccacaaa atcagccccc gaatggtggc catagggcgc tacgacggga 500

 ctcacccgtg cctggcggcc gccacccaaa cgggcaaggt ttttattcat 550

 aatcctcata cacggaacca gcatgtcagt gcatccaggg tcttccagag 600

 ccccctggaa tctgatgttt ctcttctcag cattaaccag gcagtcagct 650

 gtctgactgc aggcgtattg aaccctgagc ttggctatga tgccctttta 700

 gtggggacac agactaatct tttggcttat gatgtctaca ataattcgga 750

 tttgttctac agagaggtag cagatggggc aaatgcaatt gtgctgggga 800

 cattgggaga catttcttcc cctcttgcga ttattggtgg caattgtgct 850

 ctgcaaggtt tcaatcatga aggaagtgat ctcttttgga cggttactgg 900

 agacaatgtt aattccttgg ccttgtgtga ctttgatggt gatggaaaga 950

 aagagcttct tgttggatct gaggattttg atatccgagt ttttaaggaa 1000

 gatgagattg tggcagaaat gacagaaaca gagatagtca cctctctttg 1050

 tcccatgtat ggcagtcgat ttggttatgc cctttccaat ggcacagttg 1100

 gagtttatga caaaacatcc cgatactgga gaattaaatc gaaaaatcat 1150

 gccatgagca ttcatgcttt tgaccttaat tctgatggag tgaatgaact 1200

 gataactggt tggtccaatg ggaaggttga tgctcgaagt gaccgaactg 1250

 gggaggtcat ctttaaggac aatttttctt ctgcaattgc cggtgtggta 1300

 gagggagatt accggatgga tggccacata cagttaatct gctgctcagt 1350

 ggatggggaa atccggggct acctgcctgg cacggctgag atgaggggca 1400

 acctcatgga caccagtgca gagcaggacc tgatccgaga gctgagtcag 1450

 aagaagcaga atctgttgct ggaactccgt aactatgagg aaaatgccaa 1500

 ggctgaattg gccagtccac tgaacgaggc tgatgggcat cggggcataa 1550

 tcccagccaa taccaggctc cacaccacgc tctcagtcag cctggggaat 1600

 gagacccaaa ctgctcatac agaattacgc atttccactt ctaatgacac 1650

 catcatccga gcagtattga tttttgcaga aggaattttt acaggtgaaa 1700

 gccacgtggt acatcccagc attcacaacc tctccagttc catctgcatc 1750

 cctattgtgc ctcccaaaga tgtccctgtg gatctgcact tgaaggcatt 1800

 cgtgggttac agaagcagca cccagtttca tgtatttgaa tcgacaagac 1850

 agctccctcg attctccatg tatgcgctga ccagcctgga ccctgccagt 1900

 gagccaatca gttatgttaa ctttaccatt gcagaacggg cacagagggt 1950

 tgttgtatgg ctcggtcaga actttctgtt accagaagac actcacattc 2000

 agaatgctcc atttcaagtg tgtttcacat ctttacggaa tggcggccac 2050

 ctgcatataa aaataaaact tagtggagag atcactataa atactgatga 2100

 tattgatttg gctggtgata tcatccagtc aatggcatca ttttttgcta 2150

 ttgaagacct tcaagtagaa gcggattttc ctgtctattt tgaggaatta 2200

 cgaaaggtgc tagttaaggt ggatgaatat cattcagtgc atcagaagct 2250

 cagtgctgat atggctgatc attctaattt gatccgaagt ttgctggtcg 2300

 gagctgagga tgctcgtctg atgagggaca tgaaaacaat gaagagtcgt 2350

 tatatggaac tctatgacct taatagagac ttgctaaatg gatataaaat 2400

 tcgctgtaac aatcacacag agctgttggg aaacctcaaa gcagtaaatc 2450

 aagcaattca aagagcaggt cgtctgcggg ttggaaaacc aaagaaccag 2500

 gtgatcactg cttgtcggga tgcaattcga agcaataaca tcaacacact 2550

 gttcaaaatc atgcgagtgg ggacagcttc ttcctaggtg aggaaaatac 2600

 aggtcatgaa gttcctggca aagattttct gttaaaaacc tatgctggtt 2650

 tgctttggat cacaccctgg tgaaccccgg gtgctaagaa tgaaaataac 2700

 cttggtgagt tgtacaaatt aaagacaaag aactacatgt gaagatagac 2750

 ttgctttcta tttttaaatc agtagtagta ctgttgctga ataatactag 2800

 gtttttatgg aataggatga atgcttttga agtattaggg cttcagagtc 2850

 caattttgct tatttatggt atataaatac atattttttt cttgaaattg 2900

 caattgagtt tgtacttttc aaatagatta tctacttttt cattaaaatg 2950

 taaagatgtt aaaaaaaaaa aaaaaaaa 2978

<210> 3872
<211> 721
<212> PRT
<213> Homo sapien

<400> 3872
 Met Leu Leu Pro Val Phe Thr Leu Lys Leu Arg His Lys Ile Ser
   1               5                  10                  15

 Pro Arg Met Val Ala Ile Gly Arg Tyr Asp Gly Thr His Pro Cys
                  20                  25                  30

 Leu Ala Ala Ala Thr Gln Thr Gly Lys Val Phe Ile His Asn Pro
                  35                  40                  45

 His Thr Arg Asn Gln His Val Ser Ala Ser Arg Val Phe Gln Ser
                  50                  55                  60

 Pro Leu Glu Ser Asp Val Ser Leu Leu Ser Ile Asn Gln Ala Val
                  65                  70                  75

 Ser Cys Leu Thr Ala Gly Val Leu Asn Pro Glu Leu Gly Tyr Asp
                  80                  85                  90

 Ala Leu Leu Val Gly Thr Gln Thr Asn Leu Leu Ala Tyr Asp Val
                  95                 100                 105

 Tyr Asn Asn Ser Asp Leu Phe Tyr Arg Glu Val Ala Asp Gly Ala
                 110                 115                 120

 Asn Ala Ile Val Leu Gly Thr Leu Gly Asp Ile Ser Ser Pro Leu
                 125                 130                 135

 Ala Ile Ile Gly Gly Asn Cys Ala Leu Gln Gly Phe Asn His Glu
                 140                 145                 150

 Gly Ser Asp Leu Phe Trp Thr Val Thr Gly Asp Asn Val Asn Ser
                 155                 160                 165

 Leu Ala Leu Cys Asp Phe Asp Gly Asp Gly Lys Lys Glu Leu Leu
                 170                 175                 180

 Val Gly Ser Glu Asp Phe Asp Ile Arg Val Phe Lys Glu Asp Glu
                 185                 190                 195

 Ile Val Ala Glu Met Thr Glu Thr Glu Ile Val Thr Ser Leu Cys
                 200                 205                 210

 Pro Met Tyr Gly Ser Arg Phe Gly Tyr Ala Leu Ser Asn Gly Thr
                 215                 220                 225

 Val Gly Val Tyr Asp Lys Thr Ser Arg Tyr Trp Arg Ile Lys Ser
                 230                 235                 240

 Lys Asn His Ala Met Ser Ile His Ala Phe Asp Leu Asn Ser Asp
                 245                 250                 255

 Gly Val Asn Glu Leu Ile Thr Gly Trp Ser Asn Gly Lys Val Asp
                 260                 265                 270

 Ala Arg Ser Asp Arg Thr Gly Glu Val Ile Phe Lys Asp Asn Phe
                 275                 280                 285

 Ser Ser Ala Ile Ala Gly Val Val Glu Gly Asp Tyr Arg Met Asp
                 290                 295                 300

 Gly His Ile Gln Leu Ile Cys Cys Ser Val Asp Gly Glu Ile Arg
                 305                 310                 315

 Gly Tyr Leu Pro Gly Thr Ala Glu Met Arg Gly Asn Leu Met Asp
                 320                 325                 330

 Thr Ser Ala Glu Gln Asp Leu Ile Arg Glu Leu Ser Gln Lys Lys
                 335                 340                 345

 Gln Asn Leu Leu Leu Glu Leu Arg Asn Tyr Glu Glu Asn Ala Lys
                 350                 355                 360

 Ala Glu Leu Ala Ser Pro Leu Asn Glu Ala Asp Gly His Arg Gly
                 365                 370                 375

 Ile Ile Pro Ala Asn Thr Arg Leu His Thr Thr Leu Ser Val Ser
                 380                 385                 390

 Leu Gly Asn Glu Thr Gln Thr Ala His Thr Glu Leu Arg Ile Ser
                 395                 400                 405

 Thr Ser Asn Asp Thr Ile Ile Arg Ala Val Leu Ile Phe Ala Glu
                 410                 415                 420

 Gly Ile Phe Thr Gly Glu Ser His Val Val His Pro Ser Ile His
                 425                 430                 435

 Asn Leu Ser Ser Ser Ile Cys Ile Pro Ile Val Pro Pro Lys Asp
                 440                 445                 450

 Val Pro Val Asp Leu His Leu Lys Ala Phe Val Gly Tyr Arg Ser
                 455                 460                 465

 Ser Thr Gln Phe His Val Phe Glu Ser Thr Arg Gln Leu Pro Arg
                 470                 475                 480

 Phe Ser Met Tyr Ala Leu Thr Ser Leu Asp Pro Ala Ser Glu Pro
                 485                 490                 495

 Ile Ser Tyr Val Asn Phe Thr Ile Ala Glu Arg Ala Gln Arg Val
                 500                 505                 510

 Val Val Trp Leu Gly Gln Asn Phe Leu Leu Pro Glu Asp Thr His
                 515                 520                 525

 Ile Gln Asn Ala Pro Phe Gln Val Cys Phe Thr Ser Leu Arg Asn
                 530                 535                 540

 Gly Gly His Leu His Ile Lys Ile Lys Leu Ser Gly Glu Ile Thr
                 545                 550                 555

 Ile Asn Thr Asp Asp Ile Asp Leu Ala Gly Asp Ile Ile Gln Ser
                 560                 565                 570

 Met Ala Ser Phe Phe Ala Ile Glu Asp Leu Gln Val Glu Ala Asp
                 575                 580                 585

 Phe Pro Val Tyr Phe Glu Glu Leu Arg Lys Val Leu Val Lys Val
                 590                 595                 600

 Asp Glu Tyr His Ser Val His Gln Lys Leu Ser Ala Asp Met Ala
                 605                 610                 615

 Asp His Ser Asn Leu Ile Arg Ser Leu Leu Val Gly Ala Glu Asp
                 620                 625                 630

 Ala Arg Leu Met Arg Asp Met Lys Thr Met Lys Ser Arg Tyr Met
                 635                 640                 645

 Glu Leu Tyr Asp Leu Asn Arg Asp Leu Leu Asn Gly Tyr Lys Ile
                 650                 655                 660

 Arg Cys Asn Asn His Thr Glu Leu Leu Gly Asn Leu Lys Ala Val
                 665                 670                 675

 Asn Gln Ala Ile Gln Arg Ala Gly Arg Leu Arg Val Gly Lys Pro
                 680                 685                 690

 Lys Asn Gln Val Ile Thr Ala Cys Arg Asp Ala Ile Arg Ser Asn
                 695                 700                 705

 Asn Ile Asn Thr Leu Phe Lys Ile Met Arg Val Gly Thr Ala Ser
                 710                 715                 720

 Ser


<210> 3873
<211> 2601
<212> DNA
<213> Homo sapien

<400> 3873
 tcccccctct taaaacacga tgcctcccag gatgctagtg gcaccactgc 50

 cactgcattt cctgttggca gcagtgagca gtgaaaaccg aagcggcaga 100

 aggcagtggc agcaggcagt ggcagcaggc agtggcccag gcagaaatag 150

 ctcccgcgcg attcactgga gccttccccg ggccctggtc ccggctaccg 200

 ggactcgcgc gtccggatct caaaagcggc agaggccacc gaagggacag 250

 gaagcacttt ggtccagacc acactcccgg cacagtgcgg aaagagccgg 300

 cgggagccac tctgatcccg gacgcctcag cgcccccttg ggcttgggct 350

 tgccctcggg ccggggaagg ctgaccgcga tgccaggacg cgctcccctc 400

 cgcaccgtcc cgggcgccct gggtgcctgg ctgctgggcg gcctctgggc 450

 ctggaccctg tgcggcctgt gcagcctggg ggcggtggga gccccgcgcc 500

 cgtgccaggc gccgcagcag tgggaggggc gccaggttat gtaccagcaa 550

 agtagcgggc gcaacagccg cgccctgctc tcctacgacg ggctcaacca 600

 gcgcgtgcgg gtgctggacg agaggaaggc gctgatcccc tgcaagagat 650

 tatttgaata tattttgctg tataaggatg gagtgatgtt tcagattgac 700

 caagccacca agcagtgctc aaagatgacc ctgacacagc cctgggatcc 750

 tcttgacatt cctcaaaact ccacctttga agaccagtac tccattgggg 800

 ggcctcagga gcagatcacc gtccaggagt ggtcggacag aaagtcagct 850

 agatcctatg aaacctggat tggcatctat acagtcaagg attgctatcc 900

 tgtccaggaa acctttacca taaactacag tgtgatattg tctacgcggt 950

 tttttgacat ccagctgggt attaaagacc cctcggtgtt tacccctcca 1000

 agcacgtgcc agatggccca actggagaag atgagcgaag actgctcctg 1050

 gtgagcctgt gcatagggaa gcggcagcat cggatgtcag ccccctgcgg 1100

 ccccagctgg agatggatat gagactagtc aagatgtgaa tgctaattgg 1150

 agagaaatat aattttagga agatgcacat tgatgtgggg ttttgatgtg 1200

 tctgattttg actactcaag ctctgtttac agaagaaaat tgaatggcga 1250

 gggtgtggcc atatgaactg actagatggc taatatggac actttgggta 1300

 tttctaatgc ctgttcaggg ctggttttct gcatgcacgg gtatacacat 1350

 aatgcagtgc catgcacata gggaagggtc agtaagagaa gtttgccttg 1400

 gcagcaagta tttattgttg acattattca gaattagtga taataaaaag 1450

 cagagtgatt ttggtcaatt ttattattaa ttcttaaatt ccctgcagag 1500

 aatgccccct ttattgctgc accagggtgg gcattgctcc cactgagccc 1550

 tactccaccc tgtccctgca ctcccttggt tgccaaaaaa atgataactt 1600

 aaatcccttc cagacttaag aattttatgg catggcccaa ttgatataaa 1650

 catttagaag gaaatgaaaa gctaaaatag gaagtaatta ttcctctaaa 1700

 gaaacatttt gagcaaggca gtttagagaa tcctaatgtc tacactggca 1750

 tagcacgagc catgtaagct tctttttttt ctatgcaaga gtattgatgt 1800

 atgtgctgaa tcttcacaga cttgtcaata cacaggcagt attctaaaat 1850

 agcactgaac agggagacag gagactattg tctcctaaac ccaggactag 1900

 agttccctcg tactgtcact cctttggtca ttaaatgcac tgggcttgcc 1950

 cgcactttgg ccttcctaga acgctgcttc ataacctctc tgtctgactt 2000

 ctgcatctcc ttccaggtca gctcattcac aagagttgct cccaagcctg 2050

 gatgagttgc accttgcatc ttgagcatgc atttctcaca ataattatta 2100

 agctgtgtga taatttctgc tttcaggaca ctcatccatt atcttggctg 2150

 tgagctcctt gggtacgggt accttgtatg tttaatttta tatccctagc 2200

 acaaagcaag tgcctggcac atagtcagtg ccctaagtat tcgtagagtg 2250

 aagaatgcca gcctctcttg tccctggttt ccttatgtgt tgaatgtggt 2300

 tgagtttgtc cattgctagg gagagacttc cagtaataaa atttactatt 2350

 ctagatgctt ctactgttat gttttatctg cccatttatc tttcttagtt 2400

 accaggagaa atgtgtgaca cctatattat aatgaaaaca atcttattac 2450

 ttatagttta tctatattaa acaaatttaa ttgcatttta aagcattctt 2500

 tgatattgtt gcttttgcaa taaatatgga taatcttggt tataagggag 2550

 ttaaaacaat gctgtaataa ataaagtgtt tcatgtgatc aaaaaaaaaa 2600

 a 2601

<210> 3874
<211> 344
<212> PRT
<213> Homo sapien

<400> 3874
 Met Pro Pro Arg Met Leu Val Ala Pro Leu Pro Leu His Phe Leu
   1               5                  10                  15

 Leu Ala Ala Val Ser Ser Glu Asn Arg Ser Gly Arg Arg Gln Trp
                  20                  25                  30

 Gln Gln Ala Val Ala Ala Gly Ser Gly Pro Gly Arg Asn Ser Ser
                  35                  40                  45

 Arg Ala Ile His Trp Ser Leu Pro Arg Ala Leu Val Pro Ala Thr
                  50                  55                  60

 Gly Thr Arg Ala Ser Gly Ser Gln Lys Arg Gln Arg Pro Pro Lys
                  65                  70                  75

 Gly Gln Glu Ala Leu Trp Ser Arg Pro His Ser Arg His Ser Ala
                  80                  85                  90

 Glu Arg Ala Gly Gly Ser His Ser Asp Pro Gly Arg Leu Ser Ala
                  95                 100                 105

 Pro Leu Gly Leu Gly Leu Pro Ser Gly Arg Gly Arg Leu Thr Ala
                 110                 115                 120

 Met Pro Gly Arg Ala Pro Leu Arg Thr Val Pro Gly Ala Leu Gly
                 125                 130                 135

 Ala Trp Leu Leu Gly Gly Leu Trp Ala Trp Thr Leu Cys Gly Leu
                 140                 145                 150

 Cys Ser Leu Gly Ala Val Gly Ala Pro Arg Pro Cys Gln Ala Pro
                 155                 160                 165

 Gln Gln Trp Glu Gly Arg Gln Val Met Tyr Gln Gln Ser Ser Gly
                 170                 175                 180

 Arg Asn Ser Arg Ala Leu Leu Ser Tyr Asp Gly Leu Asn Gln Arg
                 185                 190                 195

 Val Arg Val Leu Asp Glu Arg Lys Ala Leu Ile Pro Cys Lys Arg
                 200                 205                 210

 Leu Phe Glu Tyr Ile Leu Leu Tyr Lys Asp Gly Val Met Phe Gln
                 215                 220                 225

 Ile Asp Gln Ala Thr Lys Gln Cys Ser Lys Met Thr Leu Thr Gln
                 230                 235                 240

 Pro Trp Asp Pro Leu Asp Ile Pro Gln Asn Ser Thr Phe Glu Asp
                 245                 250                 255

 Gln Tyr Ser Ile Gly Gly Pro Gln Glu Gln Ile Thr Val Gln Glu
                 260                 265                 270

 Trp Ser Asp Arg Lys Ser Ala Arg Ser Tyr Glu Thr Trp Ile Gly
                 275                 280                 285

 Ile Tyr Thr Val Lys Asp Cys Tyr Pro Val Gln Glu Thr Phe Thr
                 290                 295                 300

 Ile Asn Tyr Ser Val Ile Leu Ser Thr Arg Phe Phe Asp Ile Gln
                 305                 310                 315

 Leu Gly Ile Lys Asp Pro Ser Val Phe Thr Pro Pro Ser Thr Cys
                 320                 325                 330

 Gln Met Ala Gln Leu Glu Lys Met Ser Glu Asp Cys Ser Trp
                 335                 340

<210> 3875
<211> 1176
<212> DNA
<213> Homo sapien

<400> 3875
 agcggatttc cgcctccggg tggcgcttcc cggtgtcgtg ttctggaagc 50

 ttagcggtca ccatggagct gctgggagag tacgtcgggc aggaagggaa 100

 gccgcagaag ctgcgggtgt cctgtgaggc gccgggtgac ggcgaccctt 150

 tccagggcct gttgtctggc gtggcccaga tgaaggacat ggtaacggaa 200

 ttattcgacc ctctggtaca gggggaagtg cagcaccggg tggcggcggc 250

 tccagacgag gacttggacg gtgatgatga agatgatgca gaagatgaaa 300

 ataacattga taacagaact aacttcgatg gaccatctgc aaaacggcca 350

 aaaacaccgt cttaacaata gccttcatga catttaaaag atggctgttg 400

 tatccttatt gtcacactag gacatttaag gaagacttat gctctaattt 450

 ggaaaaagca tttgtgttgt tctcctggga caattttgtc aaagagaaaa 500

 ctggtttttc tgtttctagc aaagatagta aaggcttaga aataaaatct 550

 gttttcttga gaaataaatt tcagaccctg gaaggaaaat agaacacttc 600

 ataatgtata aaatcctcta agttggcaac tgaattttta tcattgtttt 650

 ctatttttaa aataatcatt gatttgtgtg atgtctacat cttttaactt 700

 ctggttctgt tataaagagt acatgtcacg gttcataggc agtaacattt 750

 cagagaactg acatgaacaa gtagtgaaaa ttgggcatta aatataaaaa 800

 taacagttct tcataaacag aaggaaaata aggaaataga aataccaacg 850

 agaaaggaga gtccttgaaa gagacccaag gaaaccctga attcataccc 900

 acgtcaaata tgcacatatc ctgagatgat gccactttga tgaatgtgca 950

 ttagtctgat ttatcatgta ccttaagaga gccagatggg gtatgttttt 1000

 gtgctgtgat atggtattta tacaggtaca aatataaggc cttaagtaaa 1050

 caatctgcat tgattacaat ttggatattt cctctcctcc tgtagccata 1100

 ctttgatttt gctttaaaaa gattattgaa tccttttaaa aatatatatt 1150

 cctaaaatat gaaaaaaaaa aaaaaa 1176

<210> 3876
<211> 71
<212> PRT
<213> Homo sapien

<400> 3876
 Met Thr Phe Lys Arg Trp Leu Leu Tyr Pro Tyr Cys His Thr Arg
   1               5                  10                  15

 Thr Phe Lys Glu Asp Leu Cys Ser Asn Leu Glu Lys Ala Phe Val
                  20                  25                  30

 Leu Phe Ser Trp Asp Asn Phe Val Lys Glu Lys Thr Gly Phe Ser
                  35                  40                  45

 Val Ser Ser Lys Asp Ser Lys Gly Leu Glu Ile Lys Ser Val Phe
                  50                  55                  60

 Leu Arg Asn Lys Phe Gln Thr Leu Glu Gly Lys
                  65                  70

<210> 3877
<211> 1474
<212> DNA
<213> Homo sapien

<400> 3877
 ccggggcacg ttccaggagc tgcctagggc tgaggttcca ggcctggggg 50

 tcgcttccag ctgccagatc ccgtgcagtc ctggggaccc tgagaagcac 100

 cgagccatcc ctgacccagg aactttccgc agactcgccg ccatctggga 150

 gtgaagcaac atggatgcag tcagccaagt ccccatggaa gtcgtgcttc 200

 ccaagcacat cctggatatc tgggttattg tcctcatcat cctggccacc 250

 attgtcatca tgacctcgtt gttgctgtgc ccagccactg cagtaatcat 300

 ctatcgcatg cggactcatc cgatccttag tggggctgtt tgagagcctc 350

 ccaagagggc cgggtgaggg atgaggacag gcatcctatc cccagcctct 400

 tcctgtcttc agaaaagcag caggagggac tttggggcat ggacctgagt 450

 tctggttttg attctgccac gagccagctg tgtgaatttg gtcaagggac 500

 ctaactctct gagttccagg ttccttatct ttcaaatggg gatggtgatc 550

 cctgcccttt ctacctcata gggatgtgag aaccacctga cttagtggat 600

 gtgaaagctg tttgtgatca gtaaagctac cacagatata agggtgttat 650

 gctgaatcct gagaagcttt caagaaccag agaacctgat tgctgatgat 700

 ggccttaaag gtggtgaggg agatactggg ggcagagcag actttgccag 750

 tgcccctcag gtcaaaccaa gccaagagca ccctgtcccc attccaaggg 800

 gccagcagca ctttggccca aagtattttc tttaaggtgc cattccttca 850

 tgttttctca gtttggaggg tgatgggtag agctttccag aaccttctcc 900

 attccagaat ctctgcccct gtgtaatctg aaggaaggct gtgccatctt 950

 tgggcactgc caagggagtt ggggtgatgg gcttctttct gcactggagt 1000

 ctcacatctg ttagctttga cactcaagca atgttggaaa atgcagggtg 1050

 actgagttcc ctgcccagct ttcgggatct ctggccccca tccccttgtg 1100

 tgtgtccctc tgcccagctc ctgctgtaat tagctccacg tgtaccccct 1150

 tcactccctc ccaccagctc tgcagccagc ctatggcaat tatattttaa 1200

 gaggtgttcc caggactttt gggacctact aaaacaatga tggttatttt 1250

 agatgtgatg atttatattt atgtagagat atttctggac cactcaagct 1300

 cttcgatacc aaaatcagga gcatcttggg atttattaaa ttatgtaaga 1350

 agatagcaca gatatcggga tattattgtg tgaaaatgct gcttttactt 1400

 tgatgtgatc tcattgatgt acacaaccaa gttccaataa agtgctagaa 1450

 tgtgaaaaaa aaaaaaaaaa aaaa 1474

<210> 3878
<211> 60
<212> PRT
<213> Homo sapien

<400> 3878
 Met Asp Ala Val Ser Gln Val Pro Met Glu Val Val Leu Pro Lys
   1               5                  10                  15

 His Ile Leu Asp Ile Trp Val Ile Val Leu Ile Ile Leu Ala Thr
                  20                  25                  30

 Ile Val Ile Met Thr Ser Leu Leu Leu Cys Pro Ala Thr Ala Val
                  35                  40                  45

 Ile Ile Tyr Arg Met Arg Thr His Pro Ile Leu Ser Gly Ala Val
                  50                  55                  60

<210> 3879
<211> 4954
<212> DNA
<213> Homo sapien

<400> 3879
 atcacagctt ggtgctgggg ctcagcatgg ccaggtggct aaccagggct 50

 tggtgtcaac tacatttggg atgatgacac ttggaggaca cagagccact 100

 gtgcagcagg agtcgccact gctaacagcc agagtgtccc agaagctttt 150

 gttgacaatt ccagtttccg aacaaaacat ttcggcaatg gtgagggctt 200

 cgatcccttc tctgatttgc tgtcagccat gaacggatgg atgtgatgcc 250

 tgctagccaa aaggcttccc tctgtgtgtt gcagtcctgt ggcattatgc 300

 atgccccctc ccagtgaccc caggcttttt atggctgtga gacacgttaa 350

 aatttcaggg gtaagacgtg accttttgag gtgactataa ctgaagattg 400

 ctttacagaa gccaaaaaag gtttttgagt catgatgcaa gaatctggga 450

 ctgagacaaa aagtaacggt tcagccatcc agaatgggtc gggcggcagc 500

 aaccacttac tagagtgcgg cggtcttcgg gaggggcggt ccaacggaga 550

 gacgccggcc gtggacatcg gggcagctga cctcgcccac gcccagcagc 600

 agcagcaaca ggcacttcag gtggcaagac agctccttct tcagcagcaa 650

 cagcagcagc aagttagtgg attaaaatct cccaagagga atgacaaaca 700

 accagctctt caggttcccg tgtcagtggc tatgatgaca cctcaagtta 750

 tcactcccca gcaaatgcag cagatcctcc agcaacaagt gctgagccct 800

 cagcagctcc aggttctcct ccagcagcag caggccctca tgcttcaaca 850

 gcagcagctt caagagtttt ataaaaaaca acaggaacag ttgcagcttc 900

 aacttttaca acaacaacat gctggaaaac agcctaaaga gcaacagcag 950

 gtggctaccc agcagttggc ttttcagcag cagcttttac agatgcagca 1000

 gttacagcag cagcacctcc tgtctttgca gcgccaaggc cttctgacaa 1050

 ttcagcccgg gcagcctgcc cttccccttc aacctcttgc tcaaggcatg 1100

 attccaacag aactgcagca gctctggaaa gaagtgacaa gtgctcatac 1150

 tgcagaagaa accacaggca acaatcacag cagtttggat ctgaccacga 1200

 catgtgtctc ctcctctgca ccttccaaga cctccttaat aatgaaccca 1250

 catgcctcta ccaatggaca gctctcagtc cacactccca aaagggaaag 1300

 tttgtcccat gaggagcacc cccatagcca tcctctctat ggacatggtg 1350

 tatgcaagtg gccaggctgt gaagcagtgt gcgaagattt ccaatcattt 1400

 ctaaaacatc tcaacagtga gcatgcgctg gacgatagaa gtacagccca 1450

 atgtagagta caaatgcagg ttgtacagca gttagagcta cagcttgcaa 1500

 aagacaaaga acgcctgcaa gccatgatga cccacctgca tgtgaagtct 1550

 acagaaccca aagccgcccc tcagcccttg aatctagtat caagtgtcac 1600

 tctctccaag tccgcatcgg aggcttctcc acagagctta cctcatactc 1650

 caacgacccc aaccgccccc ctgactcccg tcacccaagg cccctctgtc 1700

 atcacaacca ccagcatgca cacggtggga cccatccgca ggcggtactc 1750

 agacaaatac aacgtgccca tttcgtcagc agatattgcg cagaaccaag 1800

 aattttataa gaacgcagaa gttagaccac catttacata tgcatcttta 1850

 attaggcagg ccattctcga atctccagaa aagcagctaa cactaaatga 1900

 gatctataac tggttcacac gaatgtttgc ttacttccga cgcaacgcgg 1950

 ccacgtggaa gaatgcagtg cgtcataatc ttagtcttca caagtgtttt 2000

 gtgcgagtag aaaacgttaa aggggcagta tggacagtgg atgaagtaga 2050

 attccaaaaa cgaaggccac aaaagatcag tggtaaccct tcccttatta 2100

 aaaacatgca gagcagccac gcctactgca cacctctcaa tgcagcttta 2150

 caggcttcaa tggctgagaa tagtatacct ctatacacta ccgcttccat 2200

 gggaaatccc actctgggca acttagccag cgcaatacgg gaagagctga 2250

 acggggcaat ggagcatacc aacagcaacg agagtgacag cagtccaggc 2300

 agatctccta tgcaagccgt gcatcctgta cacgtcaaag aagagcccct 2350

 cgatccagag gaagctgaag ggcccctgtc cttagtgaca acagccaacc 2400

 acagtccaga ttttgaccat gacagagatt acgaagatga accagtaaac 2450

 gaggacatgg agtgactatc ggggcgggcc aaccccgaga atgaagattg 2500

 gaaaaaggaa aaaaaaaaaa cacgtcaaaa gttagcagtg aaattgttct 2550

 ccatttgttg tacagtctgg aggattttca ctacgttttg acaactctga 2600

 aatgtgttaa ctcttagtgc catcaagaac cccatttggg agtatttttg 2650

 atttttctac tttttgttga aaaaaggaat ttgtactctg tgcattggat 2700

 ggacttgttt ggtacttggg attttcctct cttaaccgtc aacatcagtg 2750

 ttgtaaattt gctaaactga ttcactttta gcagcagact ttgaactgca 2800

 gtcctgccaa cgttggacac tgaggacgcc cgacagagct tgtgcaccta 2850

 agctgcagac caagcctttg cccagaattt aaggattcca atggacgacc 2900

 tatttgcaca gtactgcatg ttgattatca ctgcctttac tccttttttt 2950

 tttttttttt tttttttgct tccagttggg atggggaagg cctttgtgtg 3000

 tgtattgggg ggaggggtta aaaaataatt atcccaaact ttttaatgta 3050

 ttgctttttt tttttttttc cttctactat accattttaa gttctgacct 3100

 caggcctcca tttgggccga tggcctcttg gaggcttaaa gttttctgta 3150

 ccttgtgatg aatgttaata ggtgttttta ttatacaaag ctgaatgtca 3200

 tttctcgttt gtagctttct gtcactcatt ccatcttcct tcagacatca 3250

 ccacgtttct ctaaagtcag aaaacattcc gttttggtct ttttcaaaaa 3300

 ggtcccaaat gctgcactct acacatgaag gccctctcac acagacgtga 3350

 cgtcctgcca gaaagagaat gaatgacaga aaaaaaaaag agagacaaac 3400

 tctaggaaca atgccgattc attccacgca gcagtattgg gggtggttcg 3450

 ggggaggggt gtttcggatt ttcttttttt cttttctttt attttttttt 3500

 ttttgcagca accattaata aatgccacca cattctacca gcacaaggaa 3550

 acataggcag cactgaaaaa aaaaaaaaag ctcatattaa ttagactgac 3600

 aatatggcct tggaaggctc tcccttgtgg aaccaagttg ccatgggcct 3650

 tgggtgctct gcgataacgg gtgtgggttg gttttgtttg caaaatggcc 3700

 aaaaaaaaaa ccggcttccc cgagcagctg ccctgaaagt aggggtggcg 3750

 gcggcggcgc tgagtttata cattagttca gacctacttg gtggcattaa 3800

 actgtttgaa tgcaaattcg atttcagatt gaacttgtta agggagttaa 3850

 cgagggctga gttcagcaaa tgctaaagtg ttaatttcaa atatgcaaat 3900

 ttggtactgc agtttgttat gcaatattat atcaccaacc cagtatcaca 3950

 aaaactcata gaagatatca tgtaggccct gggctttggg ggggtcccaa 4000

 acatggtatg cagaaatgtg atggttacag gtcagtacaa cctcagtcct 4050

 tagaacccct ccacacttca gctctgcacc cactttcctg tcatttattt 4100

 atataggact gtagtttttt ttagttcgag agcctttcga agcttaattt 4150

 atattctttc tttgtacctt ttttctaaaa ttaccaaaga tattacacaa 4200

 aggtaaatta tgttctctgt tttatgcttt atctgatgaa gccaaatatc 4250

 ctcttattgt tgatcaaagg aggcaaaaga atttagaggc aaatgacaag 4300

 cgataggcta ttgcaacctg agaaagagaa ctgctccttc atcgtaaatt 4350

 tagaagacca agtagataat ggaaccaaag ttgtactttt ttctagtagt 4400

 tatttttcct ttttcttttt gtgtacctct acagagacca aaactcattc 4450

 tcttaaagag attttatggg gctactgcag ataaaaatag gacacaatat 4500

 taaaggagct acagaaggaa gggagtccca tctcaaaaaa aaaatgaatg 4550

 tatgccactg caattagagt atccaataaa ggagacagtt tagagtcagg 4600

 acagaaaagc ttccataatt gaactagatt acataatagt atttctagaa 4650

 aaagagatat ttttagattg tatgccactt ttgtttaaga actgtgctgt 4700

 gatcactgta ttaattttgg tttatcttgg catatatcct tcagtttgtt 4750

 tttattttta atttttcctt tttttccgat taggctttgg tcagcatttt 4800

 tcatttaaag aaaagtaaca ctcccatcca ctcataagct tggtacaaaa 4850

 acttctctgg cagttacttt tgaagcttca ctctgctttc tgtataaagg 4900

 gcagtctgtg gtcacgcaag acttaaaaaa aaaaaaaaaa aaaaaaaaaa 4950

 aaaa 4954

<210> 3880
<211> 677
<212> PRT
<213> Homo sapien

<400> 3880
 Met Met Gln Glu Ser Gly Thr Glu Thr Lys Ser Asn Gly Ser Ala
   1               5                  10                  15

 Ile Gln Asn Gly Ser Gly Gly Ser Asn His Leu Leu Glu Cys Gly
                  20                  25                  30

 Gly Leu Arg Glu Gly Arg Ser Asn Gly Glu Thr Pro Ala Val Asp
                  35                  40                  45

 Ile Gly Ala Ala Asp Leu Ala His Ala Gln Gln Gln Gln Gln Gln
                  50                  55                  60

 Ala Leu Gln Val Ala Arg Gln Leu Leu Leu Gln Gln Gln Gln Gln
                  65                  70                  75

 Gln Gln Val Ser Gly Leu Lys Ser Pro Lys Arg Asn Asp Lys Gln
                  80                  85                  90

 Pro Ala Leu Gln Val Pro Val Ser Val Ala Met Met Thr Pro Gln
                  95                 100                 105

 Val Ile Thr Pro Gln Gln Met Gln Gln Ile Leu Gln Gln Gln Val
                 110                 115                 120

 Leu Ser Pro Gln Gln Leu Gln Val Leu Leu Gln Gln Gln Gln Ala
                 125                 130                 135

 Leu Met Leu Gln Gln Gln Gln Leu Gln Glu Phe Tyr Lys Lys Gln
                 140                 145                 150

 Gln Glu Gln Leu Gln Leu Gln Leu Leu Gln Gln Gln His Ala Gly
                 155                 160                 165

 Lys Gln Pro Lys Glu Gln Gln Gln Val Ala Thr Gln Gln Leu Ala
                 170                 175                 180

 Phe Gln Gln Gln Leu Leu Gln Met Gln Gln Leu Gln Gln Gln His
                 185                 190                 195

 Leu Leu Ser Leu Gln Arg Gln Gly Leu Leu Thr Ile Gln Pro Gly
                 200                 205                 210

 Gln Pro Ala Leu Pro Leu Gln Pro Leu Ala Gln Gly Met Ile Pro
                 215                 220                 225

 Thr Glu Leu Gln Gln Leu Trp Lys Glu Val Thr Ser Ala His Thr
                 230                 235                 240

 Ala Glu Glu Thr Thr Gly Asn Asn His Ser Ser Leu Asp Leu Thr
                 245                 250                 255

 Thr Thr Cys Val Ser Ser Ser Ala Pro Ser Lys Thr Ser Leu Ile
                 260                 265                 270

 Met Asn Pro His Ala Ser Thr Asn Gly Gln Leu Ser Val His Thr
                 275                 280                 285

 Pro Lys Arg Glu Ser Leu Ser His Glu Glu His Pro His Ser His
                 290                 295                 300

 Pro Leu Tyr Gly His Gly Val Cys Lys Trp Pro Gly Cys Glu Ala
                 305                 310                 315

 Val Cys Glu Asp Phe Gln Ser Phe Leu Lys His Leu Asn Ser Glu
                 320                 325                 330

 His Ala Leu Asp Asp Arg Ser Thr Ala Gln Cys Arg Val Gln Met
                 335                 340                 345

 Gln Val Val Gln Gln Leu Glu Leu Gln Leu Ala Lys Asp Lys Glu
                 350                 355                 360

 Arg Leu Gln Ala Met Met Thr His Leu His Val Lys Ser Thr Glu
                 365                 370                 375

 Pro Lys Ala Ala Pro Gln Pro Leu Asn Leu Val Ser Ser Val Thr
                 380                 385                 390

 Leu Ser Lys Ser Ala Ser Glu Ala Ser Pro Gln Ser Leu Pro His
                 395                 400                 405

 Thr Pro Thr Thr Pro Thr Ala Pro Leu Thr Pro Val Thr Gln Gly
                 410                 415                 420

 Pro Ser Val Ile Thr Thr Thr Ser Met His Thr Val Gly Pro Ile
                 425                 430                 435

 Arg Arg Arg Tyr Ser Asp Lys Tyr Asn Val Pro Ile Ser Ser Ala
                 440                 445                 450

 Asp Ile Ala Gln Asn Gln Glu Phe Tyr Lys Asn Ala Glu Val Arg
                 455                 460                 465

 Pro Pro Phe Thr Tyr Ala Ser Leu Ile Arg Gln Ala Ile Leu Glu
                 470                 475                 480

 Ser Pro Glu Lys Gln Leu Thr Leu Asn Glu Ile Tyr Asn Trp Phe
                 485                 490                 495

 Thr Arg Met Phe Ala Tyr Phe Arg Arg Asn Ala Ala Thr Trp Lys
                 500                 505                 510

 Asn Ala Val Arg His Asn Leu Ser Leu His Lys Cys Phe Val Arg
                 515                 520                 525

 Val Glu Asn Val Lys Gly Ala Val Trp Thr Val Asp Glu Val Glu
                 530                 535                 540

 Phe Gln Lys Arg Arg Pro Gln Lys Ile Ser Gly Asn Pro Ser Leu
                 545                 550                 555

 Ile Lys Asn Met Gln Ser Ser His Ala Tyr Cys Thr Pro Leu Asn
                 560                 565                 570

 Ala Ala Leu Gln Ala Ser Met Ala Glu Asn Ser Ile Pro Leu Tyr
                 575                 580                 585

 Thr Thr Ala Ser Met Gly Asn Pro Thr Leu Gly Asn Leu Ala Ser
                 590                 595                 600

 Ala Ile Arg Glu Glu Leu Asn Gly Ala Met Glu His Thr Asn Ser
                 605                 610                 615

 Asn Glu Ser Asp Ser Ser Pro Gly Arg Ser Pro Met Gln Ala Val
                 620                 625                 630

 His Pro Val His Val Lys Glu Glu Pro Leu Asp Pro Glu Glu Ala
                 635                 640                 645

 Glu Gly Pro Leu Ser Leu Val Thr Thr Ala Asn His Ser Pro Asp
                 650                 655                 660

 Phe Asp His Asp Arg Asp Tyr Glu Asp Glu Pro Val Asn Glu Asp
                 665                 670                 675

 Met Glu


<210> 3881
<211> 2053
<212> DNA
<213> Homo sapien

<400> 3881
 ggcacgaggg ccgtgcccgc ggagagagcg cggcgcggga ggccggcggc 50

 cggccggctg catggcgcgc tgcgagaggc tgcgcggagc ggccctgcgc 100

 gacgtgctgg gccgggcgca gggggtcctg ttcgactgtg acggggtgct 150

 gtggaacggc gagcgcgccg tgccgggcgc cccggagctg ctggagcggc 200

 tggcgcgggc cggcaaggcg gctctgtttg tgagcaacaa cagccggcgc 250

 gcgcggcccg agctggccct gcgcttcgcg cgcctcggct tcggggggct 300

 gcgcgccgag cagctcttca gctccgcgct gtgcgccgcg cgcctgctgc 350

 gccagcgcct gcccgggcct ccggacgcgc cgggcgccgt gttcgtgctg 400

 ggcggcgagg ggctgcgcgc cgagctgcgc gccgcggggc tgcgcctggc 450

 cggggacccg agcgcggggg acggcgcggc cccgcgcgtg cgcgccgtgc 500

 ttgtgggcta cgacgagcac ttctccttcg ccaagctgag ggaggcgtgc 550

 gcgcacctgc gcgaccccga gtgcctactc gtggccaccg accgtgaccc 600

 atggcacccg ctgagcgacg gcagccggac ccctggcacc gggagcctgg 650

 ccgctgcagt ggagacagcc tcgggacgcc aggccctggt ggtgggcaag 700

 cccagcccct acatgttcga gtgcatcacg gagaacttca gcatcgaccc 750

 cgcacgcacg cttatggtgg gtgaccgcct ggagaccgac atcctctttg 800

 gccaccgctg cggcatgacc actgtgctca cgctcacagg agtctcccgc 850

 ctagaagagg cccaggccta cctagcggcc ggccagcacg acctcgtgcc 900

 ccattactat gtggagagca tcgcagactt gacagagggg ttggaggact 950

 gagcccactg cacctgcagc cacaggccca cccctcccca ctccctgatc 1000

 ccgtaggtgg aggcgatggg tcacgagcca tgttaagcac aaccggctcc 1050

 ttggtccagt tctgcaccgg ggtggggctg ggacccgggg aaggtttgag 1100

 ggcccttgca accccctccc agcagtggct gggcactctt tgctgcccca 1150

 gaagctggtc ccctatggat tcatcttggc ctgacccagc caggtggcct 1200

 tatttcttcc ctgtcacctc ccctccttga aatctgggcc ctggtgcctg 1250

 ctgaagattc cctctatccc tgagtactta gtcttctccc ccttccctgg 1300

 ggcttctaga gctctctctg cccctcaggt cctggccctt gggtccttgt 1350

 caaccagagg tctagggaac cacaaccctt attgtcctgg gtggaccaat 1400

 ccaaaggcta agtgatagtg actcatcaat gttgggtcct gtggggtacc 1450

 agtttaggtt cctaagtaat agtgaccctt tcacgtcctg gagcccgagt 1500

 ggaccaatcg gaagcctaag tgacgatgac cctcgcatgt cctaggtccc 1550

 tgggtggacc catcaggacc ccaagtgata gtgacccagt ggtcttttag 1600

 atcctcagta gaacagtcca gaagcctgag agacagtggc cccttgataa 1650

 tctgggtctc acgggaccag ctaggggtcc aggtttcagt cagtaaataa 1700

 gagtggtcca cgtcctaaag acacctctcc tttacaaaga cttgtgatgc 1750

 tctggggctt ctgtggccaa gccccaccct ttcctggtca tggtacccgt 1800

 acagcgttga tggccacagc tcgaaggggg gctttcgtgt ccccctgtgc 1850

 ggtcagtgtt ttcagtacca cctctctccc gtgcccactt ggctatttac 1900

 ttatttattt attgtgtgcc agtgatggtg ggtgggggct gggccttccc 1950

 cgccacctcc acccctgttg tgacctgtcc ttccgtactt aataaagtgc 2000

 gcgtgggagt gttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2050

 aaa 2053

<210> 3882
<211> 296
<212> PRT
<213> Homo sapien

<400> 3882
 Met Ala Arg Cys Glu Arg Leu Arg Gly Ala Ala Leu Arg Asp Val
   1               5                  10                  15

 Leu Gly Arg Ala Gln Gly Val Leu Phe Asp Cys Asp Gly Val Leu
                  20                  25                  30

 Trp Asn Gly Glu Arg Ala Val Pro Gly Ala Pro Glu Leu Leu Glu
                  35                  40                  45

 Arg Leu Ala Arg Ala Gly Lys Ala Ala Leu Phe Val Ser Asn Asn
                  50                  55                  60

 Ser Arg Arg Ala Arg Pro Glu Leu Ala Leu Arg Phe Ala Arg Leu
                  65                  70                  75

 Gly Phe Gly Gly Leu Arg Ala Glu Gln Leu Phe Ser Ser Ala Leu
                  80                  85                  90

 Cys Ala Ala Arg Leu Leu Arg Gln Arg Leu Pro Gly Pro Pro Asp
                  95                 100                 105

 Ala Pro Gly Ala Val Phe Val Leu Gly Gly Glu Gly Leu Arg Ala
                 110                 115                 120

 Glu Leu Arg Ala Ala Gly Leu Arg Leu Ala Gly Asp Pro Ser Ala
                 125                 130                 135

 Gly Asp Gly Ala Ala Pro Arg Val Arg Ala Val Leu Val Gly Tyr
                 140                 145                 150

 Asp Glu His Phe Ser Phe Ala Lys Leu Arg Glu Ala Cys Ala His
                 155                 160                 165

 Leu Arg Asp Pro Glu Cys Leu Leu Val Ala Thr Asp Arg Asp Pro
                 170                 175                 180

 Trp His Pro Leu Ser Asp Gly Ser Arg Thr Pro Gly Thr Gly Ser
                 185                 190                 195

 Leu Ala Ala Ala Val Glu Thr Ala Ser Gly Arg Gln Ala Leu Val
                 200                 205                 210

 Val Gly Lys Pro Ser Pro Tyr Met Phe Glu Cys Ile Thr Glu Asn
                 215                 220                 225

 Phe Ser Ile Asp Pro Ala Arg Thr Leu Met Val Gly Asp Arg Leu
                 230                 235                 240

 Glu Thr Asp Ile Leu Phe Gly His Arg Cys Gly Met Thr Thr Val
                 245                 250                 255

 Leu Thr Leu Thr Gly Val Ser Arg Leu Glu Glu Ala Gln Ala Tyr
                 260                 265                 270

 Leu Ala Ala Gly Gln His Asp Leu Val Pro His Tyr Tyr Val Glu
                 275                 280                 285

 Ser Ile Ala Asp Leu Thr Glu Gly Leu Glu Asp
                 290                 295

<210> 3883
<211> 1214
<212> DNA
<213> Homo sapien

<400> 3883
 gtcaatcacc tcagatctct caagcagtcc agcctacgca acagtactcc 50

 acctctgcgc ctgtgcgggg agggtaaggc ggggccagca acttcctcag 100

 ctggagggag agcgcacggt ggagccgcca gttgagaagg actctgatcc 150

 ggctcagctt tccaatcagc tgcggaagga gccacgcttt cgggggttgc 200

 aagatggcgg ccaccagtgg aactgatgag ccggtttccg gggagttggt 250

 gtctgtggca catgcgcttt ctctcccagc agagtcgtat ggcaacgatc 300

 ctgacattga gatggcttgg gccatgagag caatgcagca tgctgaagtc 350

 tattacaagc tgatttcatc agttgaccca cagttcctga aactcaccaa 400

 agtagatgac caaatttact ctgagttccg gaaaaatttt gagaccctta 450

 ggatagatgt gttggaccca gaagaactca agtcagaatc agccaaagag 500

 aagtggaggc cattctgctt gaagtttaat gggattgttg aagacttcaa 550

 ctatggtact ttgctgcgac tagattgttc tcagggctac actgaggaaa 600

 acaccatctt tgcccccagg atacaattct ttgccattga aattgctcgg 650

 aaccgggaag gctataacaa agctgtttat atcagtgttc aggacaaaga 700

 aggagagaaa ggagtcaaca atggaggaga aaaaagagct gacagtggag 750

 aagaagagaa caccaagaat ggaggagaga aaggagctga tagtggagaa 800

 gaaaaagagg aaggaatcaa cagagaagac aaaactgaca aaggaggaga 850

 aaaagggaaa gaagctgaca aagaaatcaa caaaagtggt gaaaaagcta 900

 tgtaaggtat acagggaaca gcactctaga agctatgact caattgagac 950

 tacaagtacc acggtgctac ttgcacagac ccctttggtt aaatgtaaat 1000

 tcttgtacaa ttgaaggata cgcagaagga catctttcta gtctaacagt 1050

 caggagctgc tctggtcatt cccttgtatg aactggtcta aagactgtta 1100

 gtggggtgtt agttgatttt tcctggtata ctgtttcttg gctgacacta 1150

 ctggtcaagt aagaaatttg taaataaatt tcttttggtt cttataaaaa 1200

 aaaaaaaaaa aaaa 1214

<210> 3884
<211> 233
<212> PRT
<213> Homo sapien

<400> 3884
 Met Ala Ala Thr Ser Gly Thr Asp Glu Pro Val Ser Gly Glu Leu
   1               5                  10                  15

 Val Ser Val Ala His Ala Leu Ser Leu Pro Ala Glu Ser Tyr Gly
                  20                  25                  30

 Asn Asp Pro Asp Ile Glu Met Ala Trp Ala Met Arg Ala Met Gln
                  35                  40                  45

 His Ala Glu Val Tyr Tyr Lys Leu Ile Ser Ser Val Asp Pro Gln
                  50                  55                  60

 Phe Leu Lys Leu Thr Lys Val Asp Asp Gln Ile Tyr Ser Glu Phe
                  65                  70                  75

 Arg Lys Asn Phe Glu Thr Leu Arg Ile Asp Val Leu Asp Pro Glu
                  80                  85                  90

 Glu Leu Lys Ser Glu Ser Ala Lys Glu Lys Trp Arg Pro Phe Cys
                  95                 100                 105

 Leu Lys Phe Asn Gly Ile Val Glu Asp Phe Asn Tyr Gly Thr Leu
                 110                 115                 120

 Leu Arg Leu Asp Cys Ser Gln Gly Tyr Thr Glu Glu Asn Thr Ile
                 125                 130                 135

 Phe Ala Pro Arg Ile Gln Phe Phe Ala Ile Glu Ile Ala Arg Asn
                 140                 145                 150

 Arg Glu Gly Tyr Asn Lys Ala Val Tyr Ile Ser Val Gln Asp Lys
                 155                 160                 165

 Glu Gly Glu Lys Gly Val Asn Asn Gly Gly Glu Lys Arg Ala Asp
                 170                 175                 180

 Ser Gly Glu Glu Glu Asn Thr Lys Asn Gly Gly Glu Lys Gly Ala
                 185                 190                 195

 Asp Ser Gly Glu Glu Lys Glu Glu Gly Ile Asn Arg Glu Asp Lys
                 200                 205                 210

 Thr Asp Lys Gly Gly Glu Lys Gly Lys Glu Ala Asp Lys Glu Ile
                 215                 220                 225

 Asn Lys Ser Gly Glu Lys Ala Met
                 230

<210> 3885
<211> 1482
<212> DNA
<213> Homo sapien

<400> 3885
 gaggcgccgg cggccacgcc gcggaaggcg cgggccgagc agagccgggc 50

 gttggagccc gcgcgcgcat ggaggcgttg ccggcagccc cctgagggca 100

 gcggggagac aagacccggc gacctcgcgc atccctcgag ccgccacgcg 150

 ctctcgccac cgggcggcga cgggccgcgg agccggcgcg gccatggcga 200

 cgggcggcca gcagaaggag aacacgctgc ttcacctctt cgccggcggg 250

 tgtggaggca cagttggtgc tattttcact tgtccactag aagtcattaa 300

 gacacggttg cagtcttcaa gattagctct ccggacagtc tactatcctc 350

 aggttcatct ggggaccatt agtggagctg gaatggtgag accaacatcc 400

 gtgacacctg gactctttca ggttctgaag tcgatcttgg agaaagaggg 450

 accaaagtca ctttttagag gcttgggtcc aaatttggtt ggagttgcac 500

 catcaagggc tgtatacttt gcatgttact ccaaagccaa agagcaattt 550

 aatggcattt tcgtgcctaa cagcaatatt gtgcatattt tctcagctgg 600

 ctctgcagct tttatcacaa attccttaat gaatcctata tggatggtta 650

 aaacccgaat gcagctagaa cagaaagtga ggggctctaa gcagatgaat 700

 acactccagt gtgctcgtta cgtttaccag accgaaggca ttcgtggctt 750

 ctatagagga ttaactgcct cgtatgctgg aatttccgaa actataatct 800

 gctttgctat ttatgaaagt ttaaagaagt atctgaaaga agctccatta 850

 gcctcttctg caaatgggac tgagaaaaat tccacaagtt tttttggact 900

 tatggcagct gctgctcttt ctaagggctg tgcctcctgc attgcttatc 950

 cacacgaagt cataaggacg aggctccggg aagagggcac caagtacaag 1000

 tcttttgtcc agacggcgcg cctggtgttc cgggaagaag gctaccttgc 1050

 cttttataga ggactgtttg cccagcttat ccggcagatc ccaaatactg 1100

 ccattgtgtt gtctacttat gagttaattg tgtacctgtt agaagaccgt 1150

 actcagtaac aggccggaaa attgtgctct agaagaataa aactgaaaaa 1200

 ctctagagaa ttttttttcc ccattgatgt ttagaaagtt tgagactgaa 1250

 acaggaaagg ccataaaata tctggttcat atcacctgtt ggacatttcc 1300

 ttttggattc atgctttctg gaaggtttaa attcattaac gttaatagtt 1350

 aattataact tttttttaac ttaagaggat tcagggttaa gcaccaacta 1400

 aattaaatca tgctatttaa tttaagtata aaaaaaaaaa aaaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa cc 1482

<210> 3886
<211> 321
<212> PRT
<213> Homo sapien

<400> 3886
 Met Ala Thr Gly Gly Gln Gln Lys Glu Asn Thr Leu Leu His Leu
   1               5                  10                  15

 Phe Ala Gly Gly Cys Gly Gly Thr Val Gly Ala Ile Phe Thr Cys
                  20                  25                  30

 Pro Leu Glu Val Ile Lys Thr Arg Leu Gln Ser Ser Arg Leu Ala
                  35                  40                  45

 Leu Arg Thr Val Tyr Tyr Pro Gln Val His Leu Gly Thr Ile Ser
                  50                  55                  60

 Gly Ala Gly Met Val Arg Pro Thr Ser Val Thr Pro Gly Leu Phe
                  65                  70                  75

 Gln Val Leu Lys Ser Ile Leu Glu Lys Glu Gly Pro Lys Ser Leu
                  80                  85                  90

 Phe Arg Gly Leu Gly Pro Asn Leu Val Gly Val Ala Pro Ser Arg
                  95                 100                 105

 Ala Val Tyr Phe Ala Cys Tyr Ser Lys Ala Lys Glu Gln Phe Asn
                 110                 115                 120

 Gly Ile Phe Val Pro Asn Ser Asn Ile Val His Ile Phe Ser Ala
                 125                 130                 135

 Gly Ser Ala Ala Phe Ile Thr Asn Ser Leu Met Asn Pro Ile Trp
                 140                 145                 150

 Met Val Lys Thr Arg Met Gln Leu Glu Gln Lys Val Arg Gly Ser
                 155                 160                 165

 Lys Gln Met Asn Thr Leu Gln Cys Ala Arg Tyr Val Tyr Gln Thr
                 170                 175                 180

 Glu Gly Ile Arg Gly Phe Tyr Arg Gly Leu Thr Ala Ser Tyr Ala
                 185                 190                 195

 Gly Ile Ser Glu Thr Ile Ile Cys Phe Ala Ile Tyr Glu Ser Leu
                 200                 205                 210

 Lys Lys Tyr Leu Lys Glu Ala Pro Leu Ala Ser Ser Ala Asn Gly
                 215                 220                 225

 Thr Glu Lys Asn Ser Thr Ser Phe Phe Gly Leu Met Ala Ala Ala
                 230                 235                 240

 Ala Leu Ser Lys Gly Cys Ala Ser Cys Ile Ala Tyr Pro His Glu
                 245                 250                 255

 Val Ile Arg Thr Arg Leu Arg Glu Glu Gly Thr Lys Tyr Lys Ser
                 260                 265                 270

 Phe Val Gln Thr Ala Arg Leu Val Phe Arg Glu Glu Gly Tyr Leu
                 275                 280                 285

 Ala Phe Tyr Arg Gly Leu Phe Ala Gln Leu Ile Arg Gln Ile Pro
                 290                 295                 300

 Asn Thr Ala Ile Val Leu Ser Thr Tyr Glu Leu Ile Val Tyr Leu
                 305                 310                 315

 Leu Glu Asp Arg Thr Gln
                 320

<210> 3887
<211> 794
<212> DNA
<213> Homo sapien

<400> 3887
 ggcagccgtc tgtgccaccc agagccggcg ggccgctagg tccccggaga 50

 ccctgctatg gtgcgtgcgg gcgccgtggg ggctcatctc cccgcgtccg 100

 gcttggatat cttcggggac ctgaagaaga tgaacaagcg ccagctctat 150

 taccaggttt taaacttcgc catgatcgtg tcttctgcac tcatgatatg 200

 gaaaggcttg atcgtgctca caggcagtga gagccccatc gtggtggtgc 250

 tgagtggcag tatggagccg gcctttcaca gaggagacct cctgttcctc 300

 acaaatttcc gggaagaccc aatcagagct ggtgaaatag ttgtttttaa 350

 agttgaagga cgagacattc caatagttca cagagtaatc aaagttcatg 400

 aaaaagataa tggagacatc aaatttctga ctaaaggaga taataatgaa 450

 gttgatgata gaggcttgta caaagaaggc cagaactggc tggaaaagaa 500

 ggacgtggtg ggaagagcaa gagggttttt accatatgtt ggtatggtca 550

 ccataataat gaatgactat ccaaaattca agtatgctct tttggctgta 600

 atgggtgcat atgtgttact aaaacgtgaa tcctaaaatg agaagcagtt 650

 cctgggacca gattgaaatg aattctgttg aaaaagagaa aaactaatat 700

 atttgagatg ttccattttc tgtataaaag ggaacagtgt ggagatgttt 750

 ttgtcttgtc caaataaaag attcaccagt aaaaaaaaaa aaaa 794

<210> 3888
<211> 192
<212> PRT
<213> Homo sapien

<400> 3888
 Met Val Arg Ala Gly Ala Val Gly Ala His Leu Pro Ala Ser Gly
   1               5                  10                  15

 Leu Asp Ile Phe Gly Asp Leu Lys Lys Met Asn Lys Arg Gln Leu
                  20                  25                  30

 Tyr Tyr Gln Val Leu Asn Phe Ala Met Ile Val Ser Ser Ala Leu
                  35                  40                  45

 Met Ile Trp Lys Gly Leu Ile Val Leu Thr Gly Ser Glu Ser Pro
                  50                  55                  60

 Ile Val Val Val Leu Ser Gly Ser Met Glu Pro Ala Phe His Arg
                  65                  70                  75

 Gly Asp Leu Leu Phe Leu Thr Asn Phe Arg Glu Asp Pro Ile Arg
                  80                  85                  90

 Ala Gly Glu Ile Val Val Phe Lys Val Glu Gly Arg Asp Ile Pro
                  95                 100                 105

 Ile Val His Arg Val Ile Lys Val His Glu Lys Asp Asn Gly Asp
                 110                 115                 120

 Ile Lys Phe Leu Thr Lys Gly Asp Asn Asn Glu Val Asp Asp Arg
                 125                 130                 135

 Gly Leu Tyr Lys Glu Gly Gln Asn Trp Leu Glu Lys Lys Asp Val
                 140                 145                 150

 Val Gly Arg Ala Arg Gly Phe Leu Pro Tyr Val Gly Met Val Thr
                 155                 160                 165

 Ile Ile Met Asn Asp Tyr Pro Lys Phe Lys Tyr Ala Leu Leu Ala
                 170                 175                 180

 Val Met Gly Ala Tyr Val Leu Leu Lys Arg Glu Ser
                 185                 190

<210> 3889
<211> 2973
<212> DNA
<213> Homo sapien

<400> 3889
 gcggagccgg ggctggagag cggcgaccac tgcggatctc ggaaggaaga 50

 aatgatgtaa atcactcatc caaactttaa ggtcaaaggt gagaaggaag 100

 gtcaggaaga acatggcctg gccaaatgtt tttcaaagag ggtctctgct 150

 gtcccagttc agccatcatc atgttgtagt gttcctgctc actttcttca 200

 gttattcgtt gctccatgct tcacgaaaaa catttagcaa tgtcaaagtc 250

 agtatctctg agcagtggac cccaagtgct tttaacacgt cagttgagct 300

 gcctgtggag atctggagca gcaaccattt gttccccagt gcagagaaag 350

 cgactctttt cctcggcaca ctggatacca ttttcctctt ctcctatgct 400

 gtgggcctat tcatcagtgg catcgttggg gatcggttga atttgcgatg 450

 ggttctgtct tttggcatgt gctcttctgc attagtggtg tttgtctttg 500

 gtgcgctcac agaatggctg cgtttctaca acaaatggct gtactgctgc 550

 ctgtggattg tgaacggcct gctgcagtcc actggttggc cctgtgtggt 600

 tgctgttatg ggcaactggt ttgggaaagc cggacgagga gttgtttttg 650

 gtctctggag tgcctgtgct tcggtgggca acattttggg agcgtgccta 700

 gcttcttctg ttcttcagta tggttatgag tatgcctttc tggtgacggc 750

 gtctgtgcag tttgctggtg ggatcgttat cttctttgga ctcctggtgt 800

 caccagaaga aattggtctc tcgggtattg aggcagaaga aaactttgaa 850

 gaagactcac acaggccatt aattaatggt ggtgaaaatg aagacgaata 900

 tgagccgaat tattcaatcc aagatgatag ttctgttgcc caagtcaagg 950

 cgataagctt ctaccaggca tgttgccttc ctggagtcat accgtactca 1000

 ctggcctacg cctgcttgaa gttagtgaat tactccttct tcttctggct 1050

 ccccttttat ctgagtaaca acttcggctg gaaggaggcg gaagccgaca 1100

 agctgtccat ttggtacgac gttggaggga tcatagtatt tagtgtctct 1150

 gatccgggac aagctaggat ggatgtgggt tttctacttt ttcattctca 1200

 tgacaagttg tacaattgtg tttatctcgc cattaatagt gagggaaata 1250

 ttctctctcg tgctaaggag acaggctcac atattgaggg agtgaccggt 1300

 gcccgcgaga cagaaagaac aatgtcagcc acatcaggac cgctggggct 1350

 tcgagtctgc cctaatttgg gtttgtctag gagctccagc ctgatcttgg 1400

 attgtcaggc gtctctcaac actgccagcc acctgagatg ctgaccagca 1450

 gtgaaggctg cactagtttt ctacactaca ggaattactg ttgatgattt 1500

 ttgctgttgt ttcatgaatg tgccgagtga cttctgactc tgccagcatc 1550

 tttgacctct gactctgccc gcgtctttgt ttggcctatt gaggtttagc 1600

 gttttaacct taactgttgt tttggacttg aactttctct agccttgaaa 1650

 atggagtgaa caggaggcaa agccacgcgt ggtttgtgtt ggtggtatgt 1700

 tccacaaatg gaagagatca ttgcattttg ctttggtaat gagtttacag 1750

 agagtgggtc atctttgaag catcaaatcc tgatcaaatg ctcaagctgg 1800

 accgagctgc aagcctgcct tggacaaaga atccctctgt tcactgtggt 1850

 gggaaagatc acactacatg cctgttgatt ggctcagtca ctctgtgtct 1900

 gatctaaacg tcattcagcc ctagaagcat gaattgcttc aaattattgt 1950

 caacttgttc tcttccattt tcattcaaat taactttgac tcctggaagt 2000

 attgagtctt cctttcaagg accataaggt acatcagtta tcttgaacat 2050

 tctgacgtgt aaaggaccat aaggtacatc atttatcttg aacattccga 2100

 cgtgtaactc acagccgaag cactccatcc cagatttgtt gtctgggaac 2150

 tttaggatcc tctaggaagc taatctgctt agtctatttt tagaggattg 2200

 atctctggca caaccagctt cctggagtta cctcagcaga agactagaat 2250

 tagagaaaag ggaaagacct tttcttctag taagtgtcaa gtacagatgc 2300

 tctttgactt atgatggggt tatgtcccag taaacccatt ggaagtcaaa 2350

 tgcatttaat acccctgact ggacaccaca gcttagcctc gtccacccta 2400

 aatgtactca gaacacttag aattgcccac agttgggcag aatcatctaa 2450

 cacaaactct attttataat cgagtgttga atatatcatg taatttattg 2500

 aatattgtac attatgttga aattgcaacc atttcacacc attgtaaagt 2550

 ccaaaaatca gaagctgagg actgtctgta catgacattg aatcacatga 2600

 atggattact agggcctgag gggtgtccgt tctttagaaa aatgtagagt 2650

 atatatatct tcagggctgt gaattccata ctagttatca atattttaag 2700

 atcattctgt atatacatat tttaaattat gcaagcaaac taggaggaga 2750

 atgtgcaatt ttgagggata cctaatttgc attcggttag gggatatttt 2800

 tcaacctctt gctttatact ctgatatggg gtgtgtttat gaacttgtta 2850

 atgttattta atcatgcaga tttccaatca gtgtattgct catttactga 2900

 caaaaaggga aaatacgaaa cacagaaagg gaaaataaac tgacttttat 2950

 aatgaaaaaa aaaaaaaaaa aaa 2973

<210> 3890
<211> 443
<212> PRT
<213> Homo sapien

<400> 3890
 Met Ala Trp Pro Asn Val Phe Gln Arg Gly Ser Leu Leu Ser Gln
   1               5                  10                  15

 Phe Ser His His His Val Val Val Phe Leu Leu Thr Phe Phe Ser
                  20                  25                  30

 Tyr Ser Leu Leu His Ala Ser Arg Lys Thr Phe Ser Asn Val Lys
                  35                  40                  45

 Val Ser Ile Ser Glu Gln Trp Thr Pro Ser Ala Phe Asn Thr Ser
                  50                  55                  60

 Val Glu Leu Pro Val Glu Ile Trp Ser Ser Asn His Leu Phe Pro
                  65                  70                  75

 Ser Ala Glu Lys Ala Thr Leu Phe Leu Gly Thr Leu Asp Thr Ile
                  80                  85                  90

 Phe Leu Phe Ser Tyr Ala Val Gly Leu Phe Ile Ser Gly Ile Val
                  95                 100                 105

 Gly Asp Arg Leu Asn Leu Arg Trp Val Leu Ser Phe Gly Met Cys
                 110                 115                 120

 Ser Ser Ala Leu Val Val Phe Val Phe Gly Ala Leu Thr Glu Trp
                 125                 130                 135

 Leu Arg Phe Tyr Asn Lys Trp Leu Tyr Cys Cys Leu Trp Ile Val
                 140                 145                 150

 Asn Gly Leu Leu Gln Ser Thr Gly Trp Pro Cys Val Val Ala Val
                 155                 160                 165

 Met Gly Asn Trp Phe Gly Lys Ala Gly Arg Gly Val Val Phe Gly
                 170                 175                 180

 Leu Trp Ser Ala Cys Ala Ser Val Gly Asn Ile Leu Gly Ala Cys
                 185                 190                 195

 Leu Ala Ser Ser Val Leu Gln Tyr Gly Tyr Glu Tyr Ala Phe Leu
                 200                 205                 210

 Val Thr Ala Ser Val Gln Phe Ala Gly Gly Ile Val Ile Phe Phe
                 215                 220                 225

 Gly Leu Leu Val Ser Pro Glu Glu Ile Gly Leu Ser Gly Ile Glu
                 230                 235                 240

 Ala Glu Glu Asn Phe Glu Glu Asp Ser His Arg Pro Leu Ile Asn
                 245                 250                 255

 Gly Gly Glu Asn Glu Asp Glu Tyr Glu Pro Asn Tyr Ser Ile Gln
                 260                 265                 270

 Asp Asp Ser Ser Val Ala Gln Val Lys Ala Ile Ser Phe Tyr Gln
                 275                 280                 285

 Ala Cys Cys Leu Pro Gly Val Ile Pro Tyr Ser Leu Ala Tyr Ala
                 290                 295                 300

 Cys Leu Lys Leu Val Asn Tyr Ser Phe Phe Phe Trp Leu Pro Phe
                 305                 310                 315

 Tyr Leu Ser Asn Asn Phe Gly Trp Lys Glu Ala Glu Ala Asp Lys
                 320                 325                 330

 Leu Ser Ile Trp Tyr Asp Val Gly Gly Ile Ile Val Phe Ser Val
                 335                 340                 345

 Ser Asp Pro Gly Gln Ala Arg Met Asp Val Gly Phe Leu Leu Phe
                 350                 355                 360

 His Ser His Asp Lys Leu Tyr Asn Cys Val Tyr Leu Ala Ile Asn
                 365                 370                 375

 Ser Glu Gly Asn Ile Leu Ser Arg Ala Lys Glu Thr Gly Ser His
                 380                 385                 390

 Ile Glu Gly Val Thr Gly Ala Arg Glu Thr Glu Arg Thr Met Ser
                 395                 400                 405

 Ala Thr Ser Gly Pro Leu Gly Leu Arg Val Cys Pro Asn Leu Gly
                 410                 415                 420

 Leu Ser Arg Ser Ser Ser Leu Ile Leu Asp Cys Gln Ala Ser Leu
                 425                 430                 435

 Asn Thr Ala Ser His Leu Arg Cys
                 440

<210> 3891
<211> 1148
<212> DNA
<213> Homo sapien

<400> 3891
 ggcacgaggc cacgagctgt tgtgcatcca gaggtggaat tggggcccgg 50

 cattccctcc tcgtcccggg ctggcccttg cccccaccct gcaactcctg 100

 gttgagatgg gctcagccaa gagcgtccca gtcacaccag cgcggcctcc 150

 gccgcacaac aagcatctgg ctcgagtggc ggacccccgt tcacctagtg 200

 ctggcatcct gcgcactccc atccaggtgg agagctctcc acagccaggc 250

 ctaccagcag gggagcaact ggagggtctt aaacatgccc aggactcaga 300

 tccccgctct cctactcttg gtattgcacg gacacctatg aagaccagca 350

 gtggagaccc cccaagccca ctggtgaaac agctgagtga agtatttgaa 400

 actgaagact ctaaatcaaa tcttccccca gagcctgttc tgcccccaga 450

 ggcaccttta tcttctgaat tggacttgcc tctgggtacc cagttatctg 500

 ttgaggaaca gatgccacct tggaaccaga ctgagttccc ctccaaacag 550

 gtgttttcca aggaggaagc aagacagccc acagaaaccc ctgtggccag 600

 ccagagctcc gacaagccct caagggaccc tgagactccc agatcttcag 650

 gttctatgcg caatagatgg aaaccaaaca gcagcaaggt actagggaga 700

 tcccccctca ccatcctgca ggatgacaac tcccctggca ccctgacact 750

 acgacagggt aagcggcctt cacccctaag tgaaaatgtt agtgaactaa 800

 aggaaggagc cattcttgga actggacgac ttctgaaaac tggaggacga 850

 gcatgggagc aaggccagga ccatgacaag gaaaatcagc actttccctt 900

 ggtggagagc taggccctgc atggccccag caatgcagtc acccagggcc 950

 tggtgatatc tgtgtcctct caccccttct ttcccaggga tactgaggaa 1000

 tggcttgttt tcttagactc ctcctcagct accaaactgg gactcacagc 1050

 tttattgggc tttctttgtg tcttgtgtgt ttcttttata ttaaaggaag 1100

 taattttaaa tgttacttta aaaaggtaaa aaaaaaaaaa aaaaaaaa 1148

<210> 3892
<211> 268
<212> PRT
<213> Homo sapien

<400> 3892
 Met Gly Ser Ala Lys Ser Val Pro Val Thr Pro Ala Arg Pro Pro
   1               5                  10                  15

 Pro His Asn Lys His Leu Ala Arg Val Ala Asp Pro Arg Ser Pro
                  20                  25                  30

 Ser Ala Gly Ile Leu Arg Thr Pro Ile Gln Val Glu Ser Ser Pro
                  35                  40                  45

 Gln Pro Gly Leu Pro Ala Gly Glu Gln Leu Glu Gly Leu Lys His
                  50                  55                  60

 Ala Gln Asp Ser Asp Pro Arg Ser Pro Thr Leu Gly Ile Ala Arg
                  65                  70                  75

 Thr Pro Met Lys Thr Ser Ser Gly Asp Pro Pro Ser Pro Leu Val
                  80                  85                  90

 Lys Gln Leu Ser Glu Val Phe Glu Thr Glu Asp Ser Lys Ser Asn
                  95                 100                 105

 Leu Pro Pro Glu Pro Val Leu Pro Pro Glu Ala Pro Leu Ser Ser
                 110                 115                 120

 Glu Leu Asp Leu Pro Leu Gly Thr Gln Leu Ser Val Glu Glu Gln
                 125                 130                 135

 Met Pro Pro Trp Asn Gln Thr Glu Phe Pro Ser Lys Gln Val Phe
                 140                 145                 150

 Ser Lys Glu Glu Ala Arg Gln Pro Thr Glu Thr Pro Val Ala Ser
                 155                 160                 165

 Gln Ser Ser Asp Lys Pro Ser Arg Asp Pro Glu Thr Pro Arg Ser
                 170                 175                 180

 Ser Gly Ser Met Arg Asn Arg Trp Lys Pro Asn Ser Ser Lys Val
                 185                 190                 195

 Leu Gly Arg Ser Pro Leu Thr Ile Leu Gln Asp Asp Asn Ser Pro
                 200                 205                 210

 Gly Thr Leu Thr Leu Arg Gln Gly Lys Arg Pro Ser Pro Leu Ser
                 215                 220                 225

 Glu Asn Val Ser Glu Leu Lys Glu Gly Ala Ile Leu Gly Thr Gly
                 230                 235                 240

 Arg Leu Leu Lys Thr Gly Gly Arg Ala Trp Glu Gln Gly Gln Asp
                 245                 250                 255

 His Asp Lys Glu Asn Gln His Phe Pro Leu Val Glu Ser
                 260                 265

<210> 3893
<211> 3204
<212> DNA
<213> Homo sapien

<400> 3893
 agcgggtgct gggaaacatg gcgaccgagg gaatgatcct tactaaccac 50

 gaccatcaaa tccgtgtcgg agtccttaca gtgagtgata gttgcttcag 100

 gaatcttgca gaagaccgca gtgggataaa tctcaaagat ctcgtacaag 150

 atccttcttt gttgggtggg actatatcag catacaagat agtaccagat 200

 gaaatagaag aaatcaagga aaccctgata gattggtgtg atgaaaagga 250

 acttaatttg atattaacaa ctggaggaac aggatttgca ccacgagatg 300

 tcactccaga ggccacaaaa gaagtaatag aacgggaagc accagggatg 350

 gccctggcaa tgctgatggg atcacttaat gttacacctc tgggcatgct 400

 ctctaggcct gtatgtggaa tcagagggaa aacgcttata attaacctgc 450

 caggtagcaa gaaaggatct caggaatgct ttcaattcat actgccagct 500

 ctacctcatg ccattgacct tttacgtgat gccattgtaa aagtaaagga 550

 ggtgcatgat gaacttgaag atttgccttc cccacctccc cctctttccc 600

 ctcctcctac taccagcccc cataaacaga cagaagacaa aggagttcaa 650

 tgtgaggaag aggaagaaga gaagaaagac agtggtgttg cttcaacaga 700

 agatagttcc tcatcacata taactgcagc agccattgct gccaagaagc 750

 atccattcta caccagtcct gctgttgtca tggcacacgg tgaacagccc 800

 atccctggtc tcatcaatta ttcccatcat tcaacagatg aacggattcc 850

 agactccatc atttctcgtg gtgttcaggt gctcccacga gacacagcct 900

 ccctcagcac tactccttca gaatcgcctc gtgctcaggc tacatctcgc 950

 ctctctacag cttcctgccc aacaccaaaa gtccagtcca ggtgcagcag 1000

 caaggagaac attctcagag ccagtcacag tgctgtcgat atcaccaagg 1050

 tggctagaag acatcgcatg tctccttttc ctctgacatc tatggacaaa 1100

 gcctttatca cagtcctgga gatgactccg gtgcttggga cagaaatcat 1150

 caattaccga gatggaatgg ggcgagtcct tgctcaagat gtatatgcaa 1200

 aagacaattt accccccttc ccagcatcag taaaagatgg ctatgctgtc 1250

 cgagctgctg atggcccagg agatcgtttc atcattgggg aatcccaagc 1300

 tggtgaacag ccaactcaga cagtaatgcc aggacaagtc atgcgggtta 1350

 caacaggtgc tccaataccc tgcggtgctg atgcagtagt acaagtggaa 1400

 gataccgaac ttatcaggga atcagatgat ggcactgaag aacttgaagt 1450

 gcgaattctg gtgcaagctc ggccaggcca agatatcagg cccatcggcc 1500

 atgacattaa aagaggggaa tgtgttttgg ccaaaggaac ccacatgggc 1550

 ccctcagaga ttggtcttct ggcaactgta ggtgtcacag aggttgaagt 1600

 taataagttt ccagtggttg cagtcatgtc aacagggaat gagctgctaa 1650

 atcctgaaga tgacctctta ccagggaaga ttcgagacag caatcgttca 1700

 actcttctag caacaattca ggaacatggt taccccacga tcaacttggg 1750

 tattgtagga gacaacccag atgacttact caatgccttg aatgagggta 1800

 tcagtcgtgc tgatgtcatc atcacatcag ggggtgtatc catgggggaa 1850

 aaggactatc tcaagcaggt gctggacatt gatcttcatg ctcagatcca 1900

 ttttggcagg gtttttatga aaccaggctt gccaacaaca tttgcaactt 1950

 tggatattga tggtgtaaga aaaataatct ttgcactacc tgggaatcct 2000

 gtatcggctg tggtcacctg caatctcttt gttgtgcctg cactgaggaa 2050

 aatgcagggc atcttggatc ctcggccaac catcatcaaa gcaaggttat 2100

 catgtgatgt aaaacttgat cctcgtccag aataccatcg gtgtatacta 2150

 acttggcatc accaagaacc actaccttgg gcacagagta caggtaatca 2200

 aatgagcagc cgtctgatga gcatgcgcag tgccaatgga ttgttgatgc 2250

 tacctccaaa gacagaacag tacgtggagc tccacaaagg cgaggtggtg 2300

 gatgtcatgg tcattggacg gctatgatgg tcaccagcag gagaaagctt 2350

 tgatgcatgt ccacatatca ttgactgtat cctgtaatat gcaacggcac 2400

 agctagtttt cccgatttgg ataaaagttg atctgtatag tcaacatctt 2450

 gaactatatt tcaaatgaat ttaaatatct tttaaagaaa aaaacaccta 2500

 aaaataaatc ttaacagaaa attctgttct gattatatca aggcaaattt 2550

 ttcctttctt gcaaattgct ttgtgtgttc aatgctaggt ctgatagcga 2600

 tagcttttag tagacagcgg taggtgcctg cagaacttgt gtttttctca 2650

 tctttaaaat acaactactt atgctcttaa atcaaggctg tctgcttatt 2700

 tatactagcg taggcaacac ttggatttcc cttcttagta tgcttcataa 2750

 ctgctttaca gagagctttt gcttgttctt tctcatgtat ctcgtgttta 2800

 tgtgcacagt gccaaaagaa gactgactgg gtggaggctc tgccttgcct 2850

 caagaaccat cccctgcaga gcatccaggg aggtttctcg ccccaatagc 2900

 ctcacggcac agtactcttg ggcagtaact ggacaccttt tatttgaaga 2950

 aacaaactga agaaaaaatg cttccttaag tgctgacagc ctttttaacc 3000

 aatacattta aaattgtaca gaacaaaaaa ataaaatcaa agactgatct 3050

 tgtacagata ttagtgttac cagcattcat gtggaagtca agagcaaaga 3100

 caaaataatg ttaaacaatt ctgtaccata acattttctg taatgatact 3150

 gaaacttaat gaataaaaaa attccttgat cattatttaa aaaaaaaaaa 3200

 aaaa 3204

<210> 3894
<211> 769
<212> PRT
<213> Homo sapien

<400> 3894
 Met Ala Thr Glu Gly Met Ile Leu Thr Asn His Asp His Gln Ile
   1               5                  10                  15

 Arg Val Gly Val Leu Thr Val Ser Asp Ser Cys Phe Arg Asn Leu
                  20                  25                  30

 Ala Glu Asp Arg Ser Gly Ile Asn Leu Lys Asp Leu Val Gln Asp
                  35                  40                  45

 Pro Ser Leu Leu Gly Gly Thr Ile Ser Ala Tyr Lys Ile Val Pro
                  50                  55                  60

 Asp Glu Ile Glu Glu Ile Lys Glu Thr Leu Ile Asp Trp Cys Asp
                  65                  70                  75

 Glu Lys Glu Leu Asn Leu Ile Leu Thr Thr Gly Gly Thr Gly Phe
                  80                  85                  90

 Ala Pro Arg Asp Val Thr Pro Glu Ala Thr Lys Glu Val Ile Glu
                  95                 100                 105

 Arg Glu Ala Pro Gly Met Ala Leu Ala Met Leu Met Gly Ser Leu
                 110                 115                 120

 Asn Val Thr Pro Leu Gly Met Leu Ser Arg Pro Val Cys Gly Ile
                 125                 130                 135

 Arg Gly Lys Thr Leu Ile Ile Asn Leu Pro Gly Ser Lys Lys Gly
                 140                 145                 150

 Ser Gln Glu Cys Phe Gln Phe Ile Leu Pro Ala Leu Pro His Ala
                 155                 160                 165

 Ile Asp Leu Leu Arg Asp Ala Ile Val Lys Val Lys Glu Val His
                 170                 175                 180

 Asp Glu Leu Glu Asp Leu Pro Ser Pro Pro Pro Pro Leu Ser Pro
                 185                 190                 195

 Pro Pro Thr Thr Ser Pro His Lys Gln Thr Glu Asp Lys Gly Val
                 200                 205                 210

 Gln Cys Glu Glu Glu Glu Glu Glu Lys Lys Asp Ser Gly Val Ala
                 215                 220                 225

 Ser Thr Glu Asp Ser Ser Ser Ser His Ile Thr Ala Ala Ala Ile
                 230                 235                 240

 Ala Ala Lys Lys His Pro Phe Tyr Thr Ser Pro Ala Val Val Met
                 245                 250                 255

 Ala His Gly Glu Gln Pro Ile Pro Gly Leu Ile Asn Tyr Ser His
                 260                 265                 270

 His Ser Thr Asp Glu Arg Ile Pro Asp Ser Ile Ile Ser Arg Gly
                 275                 280                 285

 Val Gln Val Leu Pro Arg Asp Thr Ala Ser Leu Ser Thr Thr Pro
                 290                 295                 300

 Ser Glu Ser Pro Arg Ala Gln Ala Thr Ser Arg Leu Ser Thr Ala
                 305                 310                 315

 Ser Cys Pro Thr Pro Lys Val Gln Ser Arg Cys Ser Ser Lys Glu
                 320                 325                 330

 Asn Ile Leu Arg Ala Ser His Ser Ala Val Asp Ile Thr Lys Val
                 335                 340                 345

 Ala Arg Arg His Arg Met Ser Pro Phe Pro Leu Thr Ser Met Asp
                 350                 355                 360

 Lys Ala Phe Ile Thr Val Leu Glu Met Thr Pro Val Leu Gly Thr
                 365                 370                 375

 Glu Ile Ile Asn Tyr Arg Asp Gly Met Gly Arg Val Leu Ala Gln
                 380                 385                 390

 Asp Val Tyr Ala Lys Asp Asn Leu Pro Pro Phe Pro Ala Ser Val
                 395                 400                 405

 Lys Asp Gly Tyr Ala Val Arg Ala Ala Asp Gly Pro Gly Asp Arg
                 410                 415                 420

 Phe Ile Ile Gly Glu Ser Gln Ala Gly Glu Gln Pro Thr Gln Thr
                 425                 430                 435

 Val Met Pro Gly Gln Val Met Arg Val Thr Thr Gly Ala Pro Ile
                 440                 445                 450

 Pro Cys Gly Ala Asp Ala Val Val Gln Val Glu Asp Thr Glu Leu
                 455                 460                 465

 Ile Arg Glu Ser Asp Asp Gly Thr Glu Glu Leu Glu Val Arg Ile
                 470                 475                 480

 Leu Val Gln Ala Arg Pro Gly Gln Asp Ile Arg Pro Ile Gly His
                 485                 490                 495

 Asp Ile Lys Arg Gly Glu Cys Val Leu Ala Lys Gly Thr His Met
                 500                 505                 510

 Gly Pro Ser Glu Ile Gly Leu Leu Ala Thr Val Gly Val Thr Glu
                 515                 520                 525

 Val Glu Val Asn Lys Phe Pro Val Val Ala Val Met Ser Thr Gly
                 530                 535                 540

 Asn Glu Leu Leu Asn Pro Glu Asp Asp Leu Leu Pro Gly Lys Ile
                 545                 550                 555

 Arg Asp Ser Asn Arg Ser Thr Leu Leu Ala Thr Ile Gln Glu His
                 560                 565                 570

 Gly Tyr Pro Thr Ile Asn Leu Gly Ile Val Gly Asp Asn Pro Asp
                 575                 580                 585

 Asp Leu Leu Asn Ala Leu Asn Glu Gly Ile Ser Arg Ala Asp Val
                 590                 595                 600

 Ile Ile Thr Ser Gly Gly Val Ser Met Gly Glu Lys Asp Tyr Leu
                 605                 610                 615

 Lys Gln Val Leu Asp Ile Asp Leu His Ala Gln Ile His Phe Gly
                 620                 625                 630

 Arg Val Phe Met Lys Pro Gly Leu Pro Thr Thr Phe Ala Thr Leu
                 635                 640                 645

 Asp Ile Asp Gly Val Arg Lys Ile Ile Phe Ala Leu Pro Gly Asn
                 650                 655                 660

 Pro Val Ser Ala Val Val Thr Cys Asn Leu Phe Val Val Pro Ala
                 665                 670                 675

 Leu Arg Lys Met Gln Gly Ile Leu Asp Pro Arg Pro Thr Ile Ile
                 680                 685                 690

 Lys Ala Arg Leu Ser Cys Asp Val Lys Leu Asp Pro Arg Pro Glu
                 695                 700                 705

 Tyr His Arg Cys Ile Leu Thr Trp His His Gln Glu Pro Leu Pro
                 710                 715                 720

 Trp Ala Gln Ser Thr Gly Asn Gln Met Ser Ser Arg Leu Met Ser
                 725                 730                 735

 Met Arg Ser Ala Asn Gly Leu Leu Met Leu Pro Pro Lys Thr Glu
                 740                 745                 750

 Gln Tyr Val Glu Leu His Lys Gly Glu Val Val Asp Val Met Val
                 755                 760                 765

 Ile Gly Arg Leu


<210> 3895
<211> 782
<212> DNA
<213> Homo sapien

<400> 3895
 ggcacgaggc ccaggtaatt tgagcaaagg ccacagtgaa ctccggcgtg 50

 gctgaggaag gaggaggcac ccacaggctg ctgggaggag agcataaggc 100

 tcaaaatgga aaatcataaa tccaataata aggaaaacat aacaattgtt 150

 gatatatcca gaaaaattaa ccagcttcca gaagcagaaa ggaatctact 200

 tgaaaatgga tcggtttatg ttggattaaa tgctgctctt tgtggcctca 250

 tagcaaacag tctttttcga cgcatcttga atgtgacaaa ggctcgcata 300

 gctgctggct taccaatggc agggatacct tttcttacaa cagacttaac 350

 ttacagatgt tttgtaagtt ttcctttgaa tacaggtgat ttggattgtg 400

 aaacctgtac cataacacgg agtggactga ctggtcttgt tattggtggt 450

 ctataccctg ttttcttggc tatacctgta aatggtggtc tagcagccag 500

 gtatcaatca gctctgttac cacacaaagg gaacatctta agttactgga 550

 ttagaacttc taagcctgtc tttagaaaga tgttatttcc tattttgctc 600

 cagactatgt tttcagcata ccttgggtct gaacaatata aactacttat 650

 aaaggccctt cagttatctg aacctggcaa agaaattcac tgattttaaa 700

 caaatatgta aacaaaaata aaatggtaaa aacagaaaaa aaaaaaaaaa 750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 782

<210> 3896
<211> 195
<212> PRT
<213> Homo sapien

<400> 3896
 Met Glu Asn His Lys Ser Asn Asn Lys Glu Asn Ile Thr Ile Val
   1               5                  10                  15

 Asp Ile Ser Arg Lys Ile Asn Gln Leu Pro Glu Ala Glu Arg Asn
                  20                  25                  30

 Leu Leu Glu Asn Gly Ser Val Tyr Val Gly Leu Asn Ala Ala Leu
                  35                  40                  45

 Cys Gly Leu Ile Ala Asn Ser Leu Phe Arg Arg Ile Leu Asn Val
                  50                  55                  60

 Thr Lys Ala Arg Ile Ala Ala Gly Leu Pro Met Ala Gly Ile Pro
                  65                  70                  75

 Phe Leu Thr Thr Asp Leu Thr Tyr Arg Cys Phe Val Ser Phe Pro
                  80                  85                  90

 Leu Asn Thr Gly Asp Leu Asp Cys Glu Thr Cys Thr Ile Thr Arg
                  95                 100                 105

 Ser Gly Leu Thr Gly Leu Val Ile Gly Gly Leu Tyr Pro Val Phe
                 110                 115                 120

 Leu Ala Ile Pro Val Asn Gly Gly Leu Ala Ala Arg Tyr Gln Ser
                 125                 130                 135

 Ala Leu Leu Pro His Lys Gly Asn Ile Leu Ser Tyr Trp Ile Arg
                 140                 145                 150

 Thr Ser Lys Pro Val Phe Arg Lys Met Leu Phe Pro Ile Leu Leu
                 155                 160                 165

 Gln Thr Met Phe Ser Ala Tyr Leu Gly Ser Glu Gln Tyr Lys Leu
                 170                 175                 180

 Leu Ile Lys Ala Leu Gln Leu Ser Glu Pro Gly Lys Glu Ile His
                 185                 190                 195

<210> 3897
<211> 3979
<212> DNA
<213> Homo sapien

<400> 3897
 ggcggccgcg gcagggcggg cgccgcgcgg aggcagggcg ggcgtattca 50

 atggaagtgt gttaccagct gccggtactg cccctggaca ggccggtccc 100

 ccagcacgtc ctcagccgcc gaggagccat cagcttcagc tccagctccg 150

 ctctcttcgg ctgccccaat ccccggcagc tctctcagag gcgtggagct 200

 atttcctatg acagttctga tcagactgca ttatacattc gtatgctagg 250

 agatgtacgt gtaaggagcc gagcaggatt tgaatcagaa agaagaggtt 300

 ctcacccata tattgatttt cgtattttcc actctcaatc tgaaattgaa 350

 gtgtctgtct ctgcaaggaa tatcagaagg ctactaagtt tccagcgata 400

 tcttagatct tcacgctttt ttcgtggtac tgcggtttca aattccctaa 450

 acattttaga tgatgattat aatggacaag ccaagtgtat gctggaaaaa 500

 gttggaaatt ggaattttga tatctttcta tttgatagac taacaaatgg 550

 aaatagtcta gtaagcttaa cctttcattt atttagtctt catggattaa 600

 ttgagtactt ccatttagat atgatgaaac ttcgtagatt tttagttatg 650

 attcaagaag attaccacag tcaaaatcct taccataacg cagtccacgc 700

 tgcggatgtt actcaggcca tgcactgtta cttaaaggaa cctaagcttg 750

 ccaattctgt aactccttgg gatatcttgc tgagcttaat tgcagctgcc 800

 actcatgatc tggatcatcc aggtgttaat caacctttcc ttattaaaac 850

 taaccattac ttggcaactt tatacaagaa tacctcagta ctggaaaatc 900

 accactggag atctgcagtg ggcttattga gagaatcagg cttattctca 950

 catctgccat tagaaagcag gcaacaaatg gagacacaga taggtgctct 1000

 gatactagcc acagacatca gtcgccagaa tgagtatctg tctttgttta 1050

 ggtcccattt ggatagaggt gatttatgcc tagaagacac cagacacaga 1100

 catttggttt tacagatggc tttgaaatgt gctgatattt gtaacccatg 1150

 tcggacgtgg gaattaagca agcagtggag tgaaaaagta acggaggaat 1200

 tcttccatca aggagatata gaaaaaaaat atcatttggg tgtgagtcca 1250

 ctttgcgatc gtcacactga atctattgcc aacatccaga ttggttttat 1300

 gacttaccta gtggagcctt tatttacaga atgggccagg ttttccaata 1350

 caaggctatc ccagacaatg cttggacacg tggggctgaa taaagccagc 1400

 tggaagggac tgcagagaga acagtcgagc agtgaggaca ctgatgctgc 1450

 atttgagttg aactcacagt tattacctca ggaaaatcgg ttatcataac 1500

 ccccagaacc agtgggacaa actgcctcct ggaggttttt agaaatgtga 1550

 aatggggtct tgaggtgaga gaacttaact cttgactgcc aaggtttcca 1600

 agtgagtgat gccagccagc attatttatt tccaagattt cctctgttgg 1650

 atcatttgaa cccacttgtt aattgcaaga cccgaacata cagcaatatg 1700

 aatttggctt tcatgtgaaa ccttgaatat aaagcccagc aggagagaat 1750

 ccgaaaggag taacaaagga agttttgata tgtgccacga ctttttcaaa 1800

 gcatctaatc ttcaaaacgt caaacttgaa ttgttcagca acaatctctt 1850

 ggaatttaac cagtctgatg caacaatgtg tatcttgtac cttccactaa 1900

 gttctctctg agaaaatgga aatgtgaagt gcccagcctc tgctgcctct 1950

 ggcaagacaa tgtttacaaa tcaactctga aaatattggt tctaaattgc 2000

 cttggagcat gattgtgaag gaaccactca aacaaattta aagatcaaac 2050

 tttagactgc agctctttcc ccctggtttg cctttttctt ctttggatgc 2100

 caccaaagcc tcccatttgc tatagtttta tttcatgcac tggaaactga 2150

 gcatttatcg tagagtaccg ccaagctttc actccagtgc cgtttggcaa 2200

 tgcaattttt tttagcaatt agtttttaat ttggggtggg aggggaagaa 2250

 caccaatgtc ctagctgtat tatgattctg cactcaagac attgcatgtt 2300

 gttttcacta ctgtacactt gacctgcaca tgcgagaaaa aggtggaatg 2350

 tttaaaacac cataatcagc tcaggtattt gccaatctga aataaaagtg 2400

 ggatgggaga gcgtgtcctt cagatcaagg gtactaaagt ccctttcgct 2450

 gcagtgagtg agaggtatgt tgtgtgtgaa tgtacggatg tgtgtttggt 2500

 gatgtttgtg catgtgtgac gtgcatgtta tgtttctcca tgtgggcaaa 2550

 gatttgaaag taagctttta tttattattt tagaatgtga cataatgagc 2600

 agccacactc gggggagggg aaggttggta ggtaagctgt aacagattgc 2650

 tccagttgcc ttaaactatg cacatagcta agtgaccaaa cttcttgttt 2700

 tgatttgaaa aaagtgcatt gttttcttgt ccctcccttt gatgaaacgt 2750

 taccctttga cgggcctttt gatgtgaaca gatgttttct aggacaaact 2800

 ataaggacta attttaaact tcaaacattc cacttttgta atttgtttta 2850

 aattgtttta tgtatagtaa gcacaactgt aatctagttt taagagaaac 2900

 cggtgctttc ttttagttca tttgtatttc ccttgttact gtaaaagact 2950

 gtttattaat tgtttacagt ttgttgcaac agccattttc ttgggagaaa 3000

 gcttgagtgt aaagccattt gtaaaaggct ttgccatact cattttaata 3050

 tgtgcctgtt gctgttaact tttgatgaat aaaaacctat cttttcatga 3100

 aacttctctc tatacaaatt gaaatacata atgctttctg gttcttcttc 3150

 aaaccaaaac ttgtcaaatt catagacaag ataacagtaa aactgatgaa 3200

 agtgttccat tgttggtata ccaggaacaa ggttatagag atgaaacttc 3250

 aaagcttcac tcttcagtaa gctataagcc atctctgtaa gattgattcc 3300

 aactattgca taagaatacc ctaattttgg atgatttgaa cgggaaagaa 3350

 tctgatgagc ttcactagtg taattttcac tgaaatacac aagattgatt 3400

 aacccaagta tgcccatgcc tctgaagtct gtcttgggat catcaccctg 3450

 aaaaccaatt tcagcccact gcttggagat tctagcgttt aacttcttcg 3500

 tgggcattag aagattccaa agcttcatga gtagctcttc atgctgtagg 3550

 ttatcagaat catatggcct tttcctcaca ctttctacat ccaaatacag 3600

 ctgtttataa ccagttatct gcagtaagca catcttcatg catattttaa 3650

 aactggcatc cttctcaggg ttaatattct tttccttcat aatatcatct 3700

 acatatttgt ccacttcact ctgaacaaca tgtgtcgcct tctgtaaaac 3750

 cttattcttg gagtatgtca aggaattttc tatcctgtgt gtcctttgtg 3800

 cacctacata ggtatcaaat attcgctgca attcacactt cccagtcatc 3850

 tgtcgtaata gccatttcat ccaaaatcga aaaaagtgcc catagaagaa 3900

 ctcccacaaa gaaataaaca tttttttttc ctcacaggag cggaagaact 3950

 agggggagca ggagctgcaa tgcggccgc 3979

<210> 3898
<211> 482
<212> PRT
<213> Homo sapien

<400> 3898
 Met Glu Val Cys Tyr Gln Leu Pro Val Leu Pro Leu Asp Arg Pro
   1               5                  10                  15

 Val Pro Gln His Val Leu Ser Arg Arg Gly Ala Ile Ser Phe Ser
                  20                  25                  30

 Ser Ser Ser Ala Leu Phe Gly Cys Pro Asn Pro Arg Gln Leu Ser
                  35                  40                  45

 Gln Arg Arg Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln Thr Ala
                  50                  55                  60

 Leu Tyr Ile Arg Met Leu Gly Asp Val Arg Val Arg Ser Arg Ala
                  65                  70                  75

 Gly Phe Glu Ser Glu Arg Arg Gly Ser His Pro Tyr Ile Asp Phe
                  80                  85                  90

 Arg Ile Phe His Ser Gln Ser Glu Ile Glu Val Ser Val Ser Ala
                  95                 100                 105

 Arg Asn Ile Arg Arg Leu Leu Ser Phe Gln Arg Tyr Leu Arg Ser
                 110                 115                 120

 Ser Arg Phe Phe Arg Gly Thr Ala Val Ser Asn Ser Leu Asn Ile
                 125                 130                 135

 Leu Asp Asp Asp Tyr Asn Gly Gln Ala Lys Cys Met Leu Glu Lys
                 140                 145                 150

 Val Gly Asn Trp Asn Phe Asp Ile Phe Leu Phe Asp Arg Leu Thr
                 155                 160                 165

 Asn Gly Asn Ser Leu Val Ser Leu Thr Phe His Leu Phe Ser Leu
                 170                 175                 180

 His Gly Leu Ile Glu Tyr Phe His Leu Asp Met Met Lys Leu Arg
                 185                 190                 195

 Arg Phe Leu Val Met Ile Gln Glu Asp Tyr His Ser Gln Asn Pro
                 200                 205                 210

 Tyr His Asn Ala Val His Ala Ala Asp Val Thr Gln Ala Met His
                 215                 220                 225

 Cys Tyr Leu Lys Glu Pro Lys Leu Ala Asn Ser Val Thr Pro Trp
                 230                 235                 240

 Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala Thr His Asp Leu Asp
                 245                 250                 255

 His Pro Gly Val Asn Gln Pro Phe Leu Ile Lys Thr Asn His Tyr
                 260                 265                 270

 Leu Ala Thr Leu Tyr Lys Asn Thr Ser Val Leu Glu Asn His His
                 275                 280                 285

 Trp Arg Ser Ala Val Gly Leu Leu Arg Glu Ser Gly Leu Phe Ser
                 290                 295                 300

 His Leu Pro Leu Glu Ser Arg Gln Gln Met Glu Thr Gln Ile Gly
                 305                 310                 315

 Ala Leu Ile Leu Ala Thr Asp Ile Ser Arg Gln Asn Glu Tyr Leu
                 320                 325                 330

 Ser Leu Phe Arg Ser His Leu Asp Arg Gly Asp Leu Cys Leu Glu
                 335                 340                 345

 Asp Thr Arg His Arg His Leu Val Leu Gln Met Ala Leu Lys Cys
                 350                 355                 360

 Ala Asp Ile Cys Asn Pro Cys Arg Thr Trp Glu Leu Ser Lys Gln
                 365                 370                 375

 Trp Ser Glu Lys Val Thr Glu Glu Phe Phe His Gln Gly Asp Ile
                 380                 385                 390

 Glu Lys Lys Tyr His Leu Gly Val Ser Pro Leu Cys Asp Arg His
                 395                 400                 405

 Thr Glu Ser Ile Ala Asn Ile Gln Ile Gly Phe Met Thr Tyr Leu
                 410                 415                 420

 Val Glu Pro Leu Phe Thr Glu Trp Ala Arg Phe Ser Asn Thr Arg
                 425                 430                 435

 Leu Ser Gln Thr Met Leu Gly His Val Gly Leu Asn Lys Ala Ser
                 440                 445                 450

 Trp Lys Gly Leu Gln Arg Glu Gln Ser Ser Ser Glu Asp Thr Asp
                 455                 460                 465

 Ala Ala Phe Glu Leu Asn Ser Gln Leu Leu Pro Gln Glu Asn Arg
                 470                 475                 480

 Leu Ser


<210> 3899
<211> 2035
<212> DNA
<213> Homo sapien

<400> 3899
 tccctgtcct gcgcccgcgc gccccgggag cctacccagc acgcgctccg 50

 cgcccactgg ttccctccag ccgccgccgt ccagccgagt ccccactccg 100

 gagtcgccgc tgccgcgggg acatggtcct ctgcgttcag ggacctcgtc 150

 ctttgctggc tgtggagcgg actgggcagc ggcccctgtg ggccccgtcc 200

 ctggaactgc ccaagccagt catgcagccc ttgcctgctg gggccttcct 250

 cgaggaggtg gcagagggta ccccagccca gacagagagt gagccaaagg 300

 tgctggaccc agaggaggat ctgctgtgca tagccaagac cttctcctac 350

 cttcgggaat ctggctggta ttggggttcc attacggcca gcgaggcccg 400

 acaacacctg cagaagatgc cagaaggcac gttcttagta cgtgacagca 450

 cgcaccccag ctacctgttc acgctgtcag tgaaaaccac tcgtggcccc 500

 accaatgtac gcattgagta tgccgactcc agcttccgtc tggactccaa 550

 ctgcttgtcc aggccacgca tcctggcctt tccggatgtg gtcagccttg 600

 tgcagcacta tgtggcctcc tgcactgctg atacccgaag cgacagcccc 650

 gatcctgctc ccaccccggc cctgcctatg cctaaggagg atgcgcctag 700

 tgacccagca ctgcctgctc ctccaccagc cactgctgta cacctaaaac 750

 tggtgcagcc ctttgtacgc agaagcagtg cccgcagcct gcaacacctg 800

 tgccgccttg tcatcaaccg tctggtggcc gacgtggact gcctgccact 850

 gccccggcgc atggccgact acctccgaca gtaccccttc cagctctgac 900

 tgtacggggc aatctgccca ccctcaccca gtcgcaccct ggaggggaca 950

 tcagccccag ctggacttgg gcccccactg tccctcctcc aggcatcctg 1000

 gtgcctgcat acctctggca gctggcccag gaagagccag caagagcaag 1050

 gcatgggaga ggggaggtgt cacacaactt ggaggtaaat gcccccaggc 1100

 cgcatgtggc ttcattatac tgagccatgt gtcagaggat ggggagacag 1150

 gcaggacctt gtctcacctg tgggctgggc ccagacctcc actcgcttgc 1200

 ctgccctggc cacctgaact gtatgggcac tctcagccct ggtttttcaa 1250

 tccccagggt cgggtaggac ccctactggc agccagcctc tgtttctggg 1300

 aggatgacat gcagaggaac tgagatcgac agtgactagt gaccccttgt 1350

 tgaggggtaa gccaggctag gggactgcac aattatacac tatttattta 1400

 tttattctcc ttggggttgg tgtcaggggc gagccaaccc cacctctatg 1450

 ccctgagccc tggtagtcca gagaccccaa ctctgccctg gcttctctgg 1500

 ttcttccctg tggaaagccc atcctgagac atcttgctgg aaccaaggca 1550

 atcctggatg tcctggtact gacccacccg tctgtgaatg tgtccactct 1600

 cttctgcccc cagccatatt tggggaggat ggacaactac aataggtaag 1650

 aaaatgcagc cggagcctca gtccccagca gagcctgtgt ctcaccccct 1700

 cacaggacag agctgtatct gcatagagct ggtctcactg tggcgcaggc 1750

 cccgggggga gtgcctgtgc tgtcaggaag agggggtgct ggtttgaggg 1800

 ccaccactgc agttctgcta ggtctgcttc ctgcccagga aggtgcctgc 1850

 acatgagagg agagaaatac acgtctgata agacttcatg aaataataat 1900

 tatagcaaag aacagtttgg tggtcttttc tcttccactg atttttctgt 1950

 aatgacatta tacctttatt acctctttat tttattacct ctataataaa 2000

 atgatacctt tttcatgtaa aaaaaaaaaa aaaaa 2035

<210> 3900
<211> 258
<212> PRT
<213> Homo sapien

<400> 3900
 Met Val Leu Cys Val Gln Gly Pro Arg Pro Leu Leu Ala Val Glu
   1               5                  10                  15

 Arg Thr Gly Gln Arg Pro Leu Trp Ala Pro Ser Leu Glu Leu Pro
                  20                  25                  30

 Lys Pro Val Met Gln Pro Leu Pro Ala Gly Ala Phe Leu Glu Glu
                  35                  40                  45

 Val Ala Glu Gly Thr Pro Ala Gln Thr Glu Ser Glu Pro Lys Val
                  50                  55                  60

 Leu Asp Pro Glu Glu Asp Leu Leu Cys Ile Ala Lys Thr Phe Ser
                  65                  70                  75

 Tyr Leu Arg Glu Ser Gly Trp Tyr Trp Gly Ser Ile Thr Ala Ser
                  80                  85                  90

 Glu Ala Arg Gln His Leu Gln Lys Met Pro Glu Gly Thr Phe Leu
                  95                 100                 105

 Val Arg Asp Ser Thr His Pro Ser Tyr Leu Phe Thr Leu Ser Val
                 110                 115                 120

 Lys Thr Thr Arg Gly Pro Thr Asn Val Arg Ile Glu Tyr Ala Asp
                 125                 130                 135

 Ser Ser Phe Arg Leu Asp Ser Asn Cys Leu Ser Arg Pro Arg Ile
                 140                 145                 150

 Leu Ala Phe Pro Asp Val Val Ser Leu Val Gln His Tyr Val Ala
                 155                 160                 165

 Ser Cys Thr Ala Asp Thr Arg Ser Asp Ser Pro Asp Pro Ala Pro
                 170                 175                 180

 Thr Pro Ala Leu Pro Met Pro Lys Glu Asp Ala Pro Ser Asp Pro
                 185                 190                 195

 Ala Leu Pro Ala Pro Pro Pro Ala Thr Ala Val His Leu Lys Leu
                 200                 205                 210

 Val Gln Pro Phe Val Arg Arg Ser Ser Ala Arg Ser Leu Gln His
                 215                 220                 225

 Leu Cys Arg Leu Val Ile Asn Arg Leu Val Ala Asp Val Asp Cys
                 230                 235                 240

 Leu Pro Leu Pro Arg Arg Met Ala Asp Tyr Leu Arg Gln Tyr Pro
                 245                 250                 255

 Phe Gln Leu


<210> 3901
<211> 4098
<212> DNA
<213> Homo sapien

<400> 3901
 gccccgggaa gatggagcag tcgccgtcca cgccaccgcc gccgcccggg 50

 gctcccccgt ccctgcgggg ccagcagcag ctccagccac cagtgcccgg 100

 tctcccggcg cgagaggccc gggagccgcc ggccaggacg cccccgaggg 150

 tgtagaccgc gcccctggag agagtgataa tcttcaaaat gaagactttg 200

 gaaaatttta ggttctctat aggaactaca aaaatggaag gaaagaacat 250

 tttcaaaagg aaattatttt gaaagtatgt ttacaacaaa ctgatactat 300

 tgacagtttt tttttttaaa taataaaaca ctttaagaag attgtattta 350

 tggtaaaagg aaactggact aacaatgagg ccaaagactt ttcctgccac 400

 gacttattct ggaaatagcc ggcagcgact gcaagagatt cgtgaggggt 450

 taaaacagcc atccaagtct tcggttcagg ggctacccgc aggaccaaac 500

 agtgacactt ccctggatgc caaagtcctg gggagcaaag atgccaccag 550

 gcagcagcag cagatgagag ccaccccaaa gttcggacct tatcagaaag 600

 ccttgaggga aatcagatat tccttgttgc cttttgctaa tgaatcgggc 650

 acctctgcag ctgcagaagt gaaccggcaa atgctgcagg aactggtgaa 700

 cgcaggatgc gaccaggaga tggctggccg agctctcaag cagactggca 750

 gcaggagcat cgaggccgcc ctggagtaca tcagcaagat gggctacctg 800

 gacccgagga atgagcagat tgtgcgggtc attaagcaga cctccccagg 850

 aaaggggctc atgccaaccc cagtgacgcg gaggcccagc ttcgaaggaa 900

 ccggcgattc gtttgcgtcc taccaccagc tgagcggtac cccctacgag 950

 ggcccaagct tcggcgctga cggccccacg gcgctggagg agatgccgcg 1000

 gccgtacgtg gactaccttt tccccggagt cggcccccac gggcccggcc 1050

 accagcacca gcacccaccc aagggctacg gtgccagcgt agaggcagca 1100

 ggggcacact tcccgctgca gggcgcgcac tacgggcggc cgcacctgct 1150

 ggtgcctggg gaacccctgg gctacggagt gcagcgcagc ccctccttcc 1200

 agagcaagac gccgccggag accgggggtt acgccagcct gcccacgaag 1250

 ggccagggag gaccgccagg cgccggcctc gctttcccac cccctgccgc 1300

 cgggctctac gtgccgcacc cacaccacaa gcaggccggt cccgcggccc 1350

 accagctgca tgtgctgggc tcccgcagcc aggtgttcgc cagcgacagc 1400

 cccccgcaga gcctgctcac tccctcgcgg aacagcctca acgtggacct 1450

 gtatgaattg agcagcacct ccgtccagca gtggccggct gccaccctgg 1500

 cccgccggga ctccctgcag aagccgggcc tggaggcgcc gccgcgcgcg 1550

 cacgtggcct tccggcctga ctgcccagtg cccagcagga ccaactcctt 1600

 caacagccac cagccgcggc ccggtccgcc tggcaaggcc gagccctccc 1650

 tgcccgcccc caacaccgtg acggctgtca cggccgcgca catcttgcac 1700

 ccggtgaaga gcgtgcgtgt gctgaggccg gagccgcaga cggctgtggg 1750

 gccctcgcac cccgcctggg tgcccgcgcc tgccccggcc cccgcccccg 1800

 cccccgcccc ggctgcggag ggcttggacg ccaaggagga gcatgccctg 1850

 gcgctgggcg gcgcaggcgc cttcccgctg gacgtggagt acggaggccc 1900

 agaccggagg tgcccgcctc cgccctaccc gaagcacctg ctgctgcgca 1950

 gcaagtcgga gcagtacgac ctggacagcc tgtgcgcagg catggagcag 2000

 agcctccgtg cgggccccaa cgagcccgag ggcggcgaca agagccgcaa 2050

 aagcgccaag ggggacaaag gcggaaagga taaaaagcag attcagacct 2100

 ctcccgttcc cgtccgcaaa aacagcagag acgaagagaa gagagagtca 2150

 cgcatcaaga gctactcgcc atacgccttt aagttcttca tggagcagca 2200

 cgtggagaat gtcatcaaaa cctaccagca gaaggttaac cggaggctgc 2250

 agctggagca agaaatggcc aaagctggac tctgtgaagc tgagcaggag 2300

 cagatgcgga agatcctcta ccagaaagag tctaattaca acaggttaaa 2350

 gagggccaag atggacaagt ctatgtttgt caagatcaaa accctgggga 2400

 tcggtgcctt tggagaagtg tgccttgctt gtaaggtgga cactcacgcc 2450

 ctgtacgcca tgaagaccct aaggaaaaag gatgtcctga accggaatca 2500

 ggtggtccac gtcaaggccg agagggacat cctggccgag gcagacaatg 2550

 agtgggtggt caaactctac tactccttcc aagacaaaga cagcctgtac 2600

 tttgtgatgg actacatccc tggtggggac atgatgagcc tgctgatccg 2650

 gatggaggtc ttccctgagc acctggcccg gttctacatc gcagagctga 2700

 ctttggccat tgagagtgtc cacaagatgg gcttcatcca ccgagacatc 2750

 aagcctgata acattttgat agatctggat ggtcacatta aactcacaga 2800

 tttcggcctc tgcactgggt tcaggtggac tcacaattcc aaatattacc 2850

 agaaagggag ccatgtcaga caggacagca tggagcccag cgacctctgg 2900

 gatgatgtgt ctaactgtcg gtgtggggac aggctgaaga ccctagagca 2950

 gagggcgcgg aagcagcacc agaggtgcct ggcacattca ctggtgggga 3000

 ctccaaacta catcgcaccc gaggtgctcc tccgcaaagg gtacactcaa 3050

 ctctgtgact ggtggagtgt tggagtgatt ctcttcgaga tgctggtggg 3100

 gcagccgccc tttttggcac ctactcccac agaaacccag ctgaaggtga 3150

 tcaactggga gaacacgctc cacattccag cccaggtgaa gctgagccct 3200

 gaggccaggg acctcatcac caagctgtgc tgctccgcag accaccgcct 3250

 ggggcggaat ggggccgatg acctgaaggc ccaccccttc ttcagcgcca 3300

 ttgacttctc cagtgacatc cggaagcagc cagcccccta cgttcccacc 3350

 atcagccacc ccatggacac ctcgaatttc gaccccgtag atgaagaaag 3400

 cccttggaac gatgccagcg aaggtagcac caaggcctgg gacacactca 3450

 cctcgcccaa taacaagcat cctgagcacg cattttacga attcaccttc 3500

 cgaaggttct ttgatgacaa tggctacccc tttcgatgcc caaagccttc 3550

 aggagcagaa gcttcacagg ctgagagctc agatttagaa agctctgatc 3600

 tggtggatca gactgaaggc tgccagcctg tgtacgtgta gatgggggcc 3650

 aggcaccccc accactcgct gcctcccagg tcagggtccc ggagccggtg 3700

 ccctcacagg ccaataggga agccgagggc tgttttgttt taaattagtc 3750

 cgtcgattac ttcacttgaa attctgctct tcaccaagaa aacccaaaca 3800

 ggacactttt gaaaacagga ctcagcatcg ctttcaatag gcttttcagg 3850

 accttcactg cattaaaaca atatttttaa aaatttagta cagtttagaa 3900

 agagcactta ttttgtttat atccattttt tcttactaaa ttatagggat 3950

 taactttgac aaatcatgct gctgttattt tctacatttg tattttatcc 4000

 atagcactta ttcacattta ggaaaagaca taaaaactga agaacattga 4050

 tgagaaatct ctgtgcaata acgaaaaaaa aaaaaaaaaa aaaaaaaa 4098

<210> 3902
<211> 1088
<212> PRT
<213> Homo sapien

<400> 3902
 Met Arg Pro Lys Thr Phe Pro Ala Thr Thr Tyr Ser Gly Asn Ser
   1               5                  10                  15

 Arg Gln Arg Leu Gln Glu Ile Arg Glu Gly Leu Lys Gln Pro Ser
                  20                  25                  30

 Lys Ser Ser Val Gln Gly Leu Pro Ala Gly Pro Asn Ser Asp Thr
                  35                  40                  45

 Ser Leu Asp Ala Lys Val Leu Gly Ser Lys Asp Ala Thr Arg Gln
                  50                  55                  60

 Gln Gln Gln Met Arg Ala Thr Pro Lys Phe Gly Pro Tyr Gln Lys
                  65                  70                  75

 Ala Leu Arg Glu Ile Arg Tyr Ser Leu Leu Pro Phe Ala Asn Glu
                  80                  85                  90

 Ser Gly Thr Ser Ala Ala Ala Glu Val Asn Arg Gln Met Leu Gln
                  95                 100                 105

 Glu Leu Val Asn Ala Gly Cys Asp Gln Glu Met Ala Gly Arg Ala
                 110                 115                 120

 Leu Lys Gln Thr Gly Ser Arg Ser Ile Glu Ala Ala Leu Glu Tyr
                 125                 130                 135

 Ile Ser Lys Met Gly Tyr Leu Asp Pro Arg Asn Glu Gln Ile Val
                 140                 145                 150

 Arg Val Ile Lys Gln Thr Ser Pro Gly Lys Gly Leu Met Pro Thr
                 155                 160                 165

 Pro Val Thr Arg Arg Pro Ser Phe Glu Gly Thr Gly Asp Ser Phe
                 170                 175                 180

 Ala Ser Tyr His Gln Leu Ser Gly Thr Pro Tyr Glu Gly Pro Ser
                 185                 190                 195

 Phe Gly Ala Asp Gly Pro Thr Ala Leu Glu Glu Met Pro Arg Pro
                 200                 205                 210

 Tyr Val Asp Tyr Leu Phe Pro Gly Val Gly Pro His Gly Pro Gly
                 215                 220                 225

 His Gln His Gln His Pro Pro Lys Gly Tyr Gly Ala Ser Val Glu
                 230                 235                 240

 Ala Ala Gly Ala His Phe Pro Leu Gln Gly Ala His Tyr Gly Arg
                 245                 250                 255

 Pro His Leu Leu Val Pro Gly Glu Pro Leu Gly Tyr Gly Val Gln
                 260                 265                 270

 Arg Ser Pro Ser Phe Gln Ser Lys Thr Pro Pro Glu Thr Gly Gly
                 275                 280                 285

 Tyr Ala Ser Leu Pro Thr Lys Gly Gln Gly Gly Pro Pro Gly Ala
                 290                 295                 300

 Gly Leu Ala Phe Pro Pro Pro Ala Ala Gly Leu Tyr Val Pro His
                 305                 310                 315

 Pro His His Lys Gln Ala Gly Pro Ala Ala His Gln Leu His Val
                 320                 325                 330

 Leu Gly Ser Arg Ser Gln Val Phe Ala Ser Asp Ser Pro Pro Gln
                 335                 340                 345

 Ser Leu Leu Thr Pro Ser Arg Asn Ser Leu Asn Val Asp Leu Tyr
                 350                 355                 360

 Glu Leu Ser Ser Thr Ser Val Gln Gln Trp Pro Ala Ala Thr Leu
                 365                 370                 375

 Ala Arg Arg Asp Ser Leu Gln Lys Pro Gly Leu Glu Ala Pro Pro
                 380                 385                 390

 Arg Ala His Val Ala Phe Arg Pro Asp Cys Pro Val Pro Ser Arg
                 395                 400                 405

 Thr Asn Ser Phe Asn Ser His Gln Pro Arg Pro Gly Pro Pro Gly
                 410                 415                 420

 Lys Ala Glu Pro Ser Leu Pro Ala Pro Asn Thr Val Thr Ala Val
                 425                 430                 435

 Thr Ala Ala His Ile Leu His Pro Val Lys Ser Val Arg Val Leu
                 440                 445                 450

 Arg Pro Glu Pro Gln Thr Ala Val Gly Pro Ser His Pro Ala Trp
                 455                 460                 465

 Val Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala
                 470                 475                 480

 Ala Glu Gly Leu Asp Ala Lys Glu Glu His Ala Leu Ala Leu Gly
                 485                 490                 495

 Gly Ala Gly Ala Phe Pro Leu Asp Val Glu Tyr Gly Gly Pro Asp
                 500                 505                 510

 Arg Arg Cys Pro Pro Pro Pro Tyr Pro Lys His Leu Leu Leu Arg
                 515                 520                 525

 Ser Lys Ser Glu Gln Tyr Asp Leu Asp Ser Leu Cys Ala Gly Met
                 530                 535                 540

 Glu Gln Ser Leu Arg Ala Gly Pro Asn Glu Pro Glu Gly Gly Asp
                 545                 550                 555

 Lys Ser Arg Lys Ser Ala Lys Gly Asp Lys Gly Gly Lys Asp Lys
                 560                 565                 570

 Lys Gln Ile Gln Thr Ser Pro Val Pro Val Arg Lys Asn Ser Arg
                 575                 580                 585

 Asp Glu Glu Lys Arg Glu Ser Arg Ile Lys Ser Tyr Ser Pro Tyr
                 590                 595                 600

 Ala Phe Lys Phe Phe Met Glu Gln His Val Glu Asn Val Ile Lys
                 605                 610                 615

 Thr Tyr Gln Gln Lys Val Asn Arg Arg Leu Gln Leu Glu Gln Glu
                 620                 625                 630

 Met Ala Lys Ala Gly Leu Cys Glu Ala Glu Gln Glu Gln Met Arg
                 635                 640                 645

 Lys Ile Leu Tyr Gln Lys Glu Ser Asn Tyr Asn Arg Leu Lys Arg
                 650                 655                 660

 Ala Lys Met Asp Lys Ser Met Phe Val Lys Ile Lys Thr Leu Gly
                 665                 670                 675

 Ile Gly Ala Phe Gly Glu Val Cys Leu Ala Cys Lys Val Asp Thr
                 680                 685                 690

 His Ala Leu Tyr Ala Met Lys Thr Leu Arg Lys Lys Asp Val Leu
                 695                 700                 705

 Asn Arg Asn Gln Val Val His Val Lys Ala Glu Arg Asp Ile Leu
                 710                 715                 720

 Ala Glu Ala Asp Asn Glu Trp Val Val Lys Leu Tyr Tyr Ser Phe
                 725                 730                 735

 Gln Asp Lys Asp Ser Leu Tyr Phe Val Met Asp Tyr Ile Pro Gly
                 740                 745                 750

 Gly Asp Met Met Ser Leu Leu Ile Arg Met Glu Val Phe Pro Glu
                 755                 760                 765

 His Leu Ala Arg Phe Tyr Ile Ala Glu Leu Thr Leu Ala Ile Glu
                 770                 775                 780

 Ser Val His Lys Met Gly Phe Ile His Arg Asp Ile Lys Pro Asp
                 785                 790                 795

 Asn Ile Leu Ile Asp Leu Asp Gly His Ile Lys Leu Thr Asp Phe
                 800                 805                 810

 Gly Leu Cys Thr Gly Phe Arg Trp Thr His Asn Ser Lys Tyr Tyr
                 815                 820                 825

 Gln Lys Gly Ser His Val Arg Gln Asp Ser Met Glu Pro Ser Asp
                 830                 835                 840

 Leu Trp Asp Asp Val Ser Asn Cys Arg Cys Gly Asp Arg Leu Lys
                 845                 850                 855

 Thr Leu Glu Gln Arg Ala Arg Lys Gln His Gln Arg Cys Leu Ala
                 860                 865                 870

 His Ser Leu Val Gly Thr Pro Asn Tyr Ile Ala Pro Glu Val Leu
                 875                 880                 885

 Leu Arg Lys Gly Tyr Thr Gln Leu Cys Asp Trp Trp Ser Val Gly
                 890                 895                 900

 Val Ile Leu Phe Glu Met Leu Val Gly Gln Pro Pro Phe Leu Ala
                 905                 910                 915

 Pro Thr Pro Thr Glu Thr Gln Leu Lys Val Ile Asn Trp Glu Asn
                 920                 925                 930

 Thr Leu His Ile Pro Ala Gln Val Lys Leu Ser Pro Glu Ala Arg
                 935                 940                 945

 Asp Leu Ile Thr Lys Leu Cys Cys Ser Ala Asp His Arg Leu Gly
                 950                 955                 960

 Arg Asn Gly Ala Asp Asp Leu Lys Ala His Pro Phe Phe Ser Ala
                 965                 970                 975

 Ile Asp Phe Ser Ser Asp Ile Arg Lys Gln Pro Ala Pro Tyr Val
                 980                 985                 990

 Pro Thr Ile Ser His Pro Met Asp Thr Ser Asn Phe Asp Pro Val
                 995                1000                1005

 Asp Glu Glu Ser Pro Trp Asn Asp Ala Ser Glu Gly Ser Thr Lys
                1010                1015                1020

 Ala Trp Asp Thr Leu Thr Ser Pro Asn Asn Lys His Pro Glu His
                1025                1030                1035

 Ala Phe Tyr Glu Phe Thr Phe Arg Arg Phe Phe Asp Asp Asn Gly
                1040                1045                1050

 Tyr Pro Phe Arg Cys Pro Lys Pro Ser Gly Ala Glu Ala Ser Gln
                1055                1060                1065

 Ala Glu Ser Ser Asp Leu Glu Ser Ser Asp Leu Val Asp Gln Thr
                1070                1075                1080

 Glu Gly Cys Gln Pro Val Tyr Val
                1085

<210> 3903
<211> 2003
<212> DNA
<213> Homo sapien

<400> 3903
 ggaatggggc gggacttcca gtaggaggcg gcaagtttga aaagtgatga 50

 cggttgacgt ttgctgattt ttgactttgc ttgtagctgc tccccgaact 100

 cgccgtcttc ctgtcggcgg ccggcactgt aggtgagcgc gagaggacgg 150

 aggaaggaag cctgcagaca gacgccttct ccatcccaag gcgcgggcag 200

 gtgccgggac gctgggcctg gcggtgtttt cgtcgtgctc agcggtggga 250

 ggaggcggaa gaaaccagag cctgggagat taacaggaaa cttccaagat 300

 ggaaactttg tctttcccca gatataatgt agctgagatt gtgattcata 350

 ttcgcaataa gatcttaaca ggagctgatg gtaaaaacct caccaagaat 400

 gatctttatc caaatccaaa gcctgaagtc ttgcacatga tctacatgag 450

 agccttacaa atagtctatg gaattcgact ggaacatttt tacatgatgc 500

 cagtgaactc tgaagtcatg tatccacatt taatggaagg cttcttacca 550

 ttcagcaatt tagttactca tctggactca tttttgccta tctgccgggt 600

 gaatgacttt gagactgctg atattctatg tccaaaagca aaacggacaa 650

 gtcggttttt aagtggcatt atcaacttta ttcacttcag agaagcatgc 700

 cgtgaaacgt atatggaatt tctttggcaa tataaatcct ctgcggacaa 750

 aatgcaacag ttaaacgccg cacaccagga ggcattaatg aaactggaga 800

 gacttgattc tgttccagtt gaagagcaag aagagttcaa gcagctttca 850

 gatggaattc aggagctaca acaatcacta aatcaggatt ttcatcaaaa 900

 aacgatagtg ctgcaagagg gaaattccca aaagaagtca aatatttcag 950

 agaaaaccaa gcgtttgaat gaactaaaat tgttggtggt ttctttgaaa 1000

 gaaatacaag agagtttgaa aacaaaaatt gtggattctc cagagaagtt 1050

 aaagaattat aaagaaaaaa tgaaagatac ggtccagaag cttaaaaatg 1100

 ccagacaaga agtggtggag aaatatgaaa tctatggaga ctcagttgac 1150

 tgcctgcctt catgtcagtt ggaagtgcag ttatatcaaa agaaaataca 1200

 ggacctttca gataataggg aaaaattagc cagtatctta aaggagagcc 1250

 tgaacttgga ggaccaaatt gagagtgatg agtcagaact gaagaaattg 1300

 aagactgaag aaaattcgtt caaaagactg atgattgtga agaaggaaaa 1350

 acttgccaca gcacaattca aaataaataa gaagcatgaa gatgttaagc 1400

 aatacaaacg cacagtaatt gaggattgca ataaagttca agaaaaaaga 1450

 ggtgctgtct atgaacgagt aaccacaatt aatcaagaaa tccaaaaaat 1500

 taaacttgga attcaacaac taaaagatgc tgctgaaagg gagaaactga 1550

 agtcccagga aatatttcta aacttgaaaa ctgctttgga gaaataccac 1600

 gacggtattg aaaaggcagc agaggactcc tatgctaaga tagatgagaa 1650

 gacagctgaa ctgaagagga agatgttcaa aatgtcaacc tgattaacaa 1700

 aattacatgt ctttttgtaa atggcttgcc atcttttaat tttctattta 1750

 gaaagaaaag ttgaagcgaa tggaagtatc agaagtacca aataatgttg 1800

 gcttcatcag tttttataca ctctcataag tagttaataa gatgaattta 1850

 atgtaggctt ttattaattt ataattaaaa taacttgtgc agctattcat 1900

 gtctctactc tgccccttgt tgtaaatagt ttgagtaaaa caaaactagt 1950

 tacctttgaa atatatatat ttttttctgt taaaaaaaaa aaaaaaaaaa 2000

 aaa 2003

<210> 3904
<211> 464
<212> PRT
<213> Homo sapien

<400> 3904
 Met Glu Thr Leu Ser Phe Pro Arg Tyr Asn Val Ala Glu Ile Val
   1               5                  10                  15

 Ile His Ile Arg Asn Lys Ile Leu Thr Gly Ala Asp Gly Lys Asn
                  20                  25                  30

 Leu Thr Lys Asn Asp Leu Tyr Pro Asn Pro Lys Pro Glu Val Leu
                  35                  40                  45

 His Met Ile Tyr Met Arg Ala Leu Gln Ile Val Tyr Gly Ile Arg
                  50                  55                  60

 Leu Glu His Phe Tyr Met Met Pro Val Asn Ser Glu Val Met Tyr
                  65                  70                  75

 Pro His Leu Met Glu Gly Phe Leu Pro Phe Ser Asn Leu Val Thr
                  80                  85                  90

 His Leu Asp Ser Phe Leu Pro Ile Cys Arg Val Asn Asp Phe Glu
                  95                 100                 105

 Thr Ala Asp Ile Leu Cys Pro Lys Ala Lys Arg Thr Ser Arg Phe
                 110                 115                 120

 Leu Ser Gly Ile Ile Asn Phe Ile His Phe Arg Glu Ala Cys Arg
                 125                 130                 135

 Glu Thr Tyr Met Glu Phe Leu Trp Gln Tyr Lys Ser Ser Ala Asp
                 140                 145                 150

 Lys Met Gln Gln Leu Asn Ala Ala His Gln Glu Ala Leu Met Lys
                 155                 160                 165

 Leu Glu Arg Leu Asp Ser Val Pro Val Glu Glu Gln Glu Glu Phe
                 170                 175                 180

 Lys Gln Leu Ser Asp Gly Ile Gln Glu Leu Gln Gln Ser Leu Asn
                 185                 190                 195

 Gln Asp Phe His Gln Lys Thr Ile Val Leu Gln Glu Gly Asn Ser
                 200                 205                 210

 Gln Lys Lys Ser Asn Ile Ser Glu Lys Thr Lys Arg Leu Asn Glu
                 215                 220                 225

 Leu Lys Leu Leu Val Val Ser Leu Lys Glu Ile Gln Glu Ser Leu
                 230                 235                 240

 Lys Thr Lys Ile Val Asp Ser Pro Glu Lys Leu Lys Asn Tyr Lys
                 245                 250                 255

 Glu Lys Met Lys Asp Thr Val Gln Lys Leu Lys Asn Ala Arg Gln
                 260                 265                 270

 Glu Val Val Glu Lys Tyr Glu Ile Tyr Gly Asp Ser Val Asp Cys
                 275                 280                 285

 Leu Pro Ser Cys Gln Leu Glu Val Gln Leu Tyr Gln Lys Lys Ile
                 290                 295                 300

 Gln Asp Leu Ser Asp Asn Arg Glu Lys Leu Ala Ser Ile Leu Lys
                 305                 310                 315

 Glu Ser Leu Asn Leu Glu Asp Gln Ile Glu Ser Asp Glu Ser Glu
                 320                 325                 330

 Leu Lys Lys Leu Lys Thr Glu Glu Asn Ser Phe Lys Arg Leu Met
                 335                 340                 345

 Ile Val Lys Lys Glu Lys Leu Ala Thr Ala Gln Phe Lys Ile Asn
                 350                 355                 360

 Lys Lys His Glu Asp Val Lys Gln Tyr Lys Arg Thr Val Ile Glu
                 365                 370                 375

 Asp Cys Asn Lys Val Gln Glu Lys Arg Gly Ala Val Tyr Glu Arg
                 380                 385                 390

 Val Thr Thr Ile Asn Gln Glu Ile Gln Lys Ile Lys Leu Gly Ile
                 395                 400                 405

 Gln Gln Leu Lys Asp Ala Ala Glu Arg Glu Lys Leu Lys Ser Gln
                 410                 415                 420

 Glu Ile Phe Leu Asn Leu Lys Thr Ala Leu Glu Lys Tyr His Asp
                 425                 430                 435

 Gly Ile Glu Lys Ala Ala Glu Asp Ser Tyr Ala Lys Ile Asp Glu
                 440                 445                 450

 Lys Thr Ala Glu Leu Lys Arg Lys Met Phe Lys Met Ser Thr
                 455                 460

<210> 3905
<211> 4633
<212> DNA
<213> Homo sapien

<400> 3905
 gccctccatt gtctccacgg cggcgaggag cgccggcgag cgcagcccgg 50

 gaccgagcgg ggcggcgcgg ctggcggggc cggcggcggc tgaagcgaga 100

 gcgcgacgcg acgcgaccgc ggcttcccga gctgcgcctg gccgcccagc 150

 gccgcggccc gcccgaggcc tggaggggtc cgggccgccg tccatggtcg 200

 cggcgtcctg aggcggggga cgcgcccggc gcccccggcc ctcctccgcc 250

 tcctcccgcg gggcgggcgg cctcctccgg cgcctccccg cgcccgcccg 300

 ccgctcgccg ccgcctccct ccctccttcc ctgcggctcc cccggctttc 350

 ggagcccggg ggcggcctgt ggcgcgcgga gcccgcgccg gactgcgcct 400

 ctttggacct tgaggggaaa catgcgtttg ccttggatcg tttgaaattc 450

 tgagtttggg atccccgccc gcccgcctgc ctcttccgcc ccgcgggttt 500

 tttccttttt tccttttgct ttttttcctt ttctccctcc gggtctcctt 550

 tttgactccc tcccccttta tgctcgccca gccctccccc tgctgctgag 600

 aagtggggga gggtctcggc ctccaggttc ccgccccacc ggggcccggg 650

 cgagcatggg gggcaagcag agcacggcgg cccgctcccg gggccccttc 700

 ccgggggtct ccaccgatga cagcgccgtg ccgccgccgg gaggggcgcc 750

 ccatttcggg cactaccgga cgggcggcgg ggccatgggg ctgcgcagcc 800

 gctcggtcag ctcggtggca ggcatgggca tggaccccag cacggccggg 850

 ggggtgccct ttggcctcta cacccccgcc tcccggggca ccggcgactc 900

 cgagagggcg cccggcggcg gagggtctgc gtccgactcc acctatgccc 950

 atggcaatgg ttaccaggag acgggcggcg gtcaccatag agacgggatg 1000

 ctgtacctgg gctcccgagc ctcgctggcg gatgctctac ctctgcacat 1050

 cgcacccagg tggttcagct cgcatagtgg tttcaagtgc cccatttgct 1100

 ccaagtctgt ggcttctgac gagatggaaa tgcactttat aatgtgtttg 1150

 agcaaacctc gcctctccta caacgatgat gtgctgacta aagacgcggg 1200

 tgagtgtgtg atctgcctgg aggagctgct gcagggggac acgatagcca 1250

 ggctgccctg cctgtgcatc tatcacaaaa gctgcataga ctcgtggttt 1300

 gaagtgaaca gatcttgtcc ggaacaccct gcggactgac ctgcgggctt 1350

 gcttgctgac tcctctcaaa gggacagagc gcccctgctc cagggaggag 1400

 gctcaccgga ccctggggca gagctgagct tgggacacca gcgggaacag 1450

 ggcacccctt ctgcactgac ttccagatca tggttctccc ttcctccctg 1500

 aggacaccaa attggatgag agcaagtttg agagaagaat gaatcaactg 1550

 ctatccttcc cctcacccct cagcccagga gggaaagggc attttctttt 1600

 tcatctttga aaggcattgt gggtctgtct ttaaagtgtt tacaaaaaaa 1650

 aattatataa aaaaaaagtc tagtgtcgac tggtgttttc cctcgtgatg 1700

 tttacagctt gctgtttgct gcccagccat aacccactca gtgacagacg 1750

 aacacagcta aggcctcgct gccagccttc tgacggcggg cgagcacacg 1800

 gtctcttccc ctgccccaac tggccctctc caccaccaac ttctctactt 1850

 tgggtttgtt tggttttttc cctctatttt tctggctggt tttttgctct 1900

 tttctcccct tgagacccta atatcttgac ttcattgcca aaaaacaacc 1950

 cattgagaac tttcttccta ctgatcccat ctcttttccc ttctttcctc 2000

 ctggttccgg tcagttcaga ggatttaaca atcacaagtg tcctgcaaaa 2050

 atgcctgaac attattctta ggccctcgtg gatttttttt ttcagaaaac 2100

 ttaaacaaaa aaagacttac taagaaatat gtacagctac ccctgttttc 2150

 aggcactatg tttgagaaca ttttagccat tgatgttcac acgtggcatc 2200

 agcccatgca agataggttt ctgtatttat atattaaaat acaaaaaaaa 2250

 acttataaaa tgtttaaaaa aatgttcaaa gcttgggaga aaagctttct 2300

 tcattagtca aggtgttttg atatggtatt aaaatgtcta ataaaagatg 2350

 gcactgcgtg attttatttt aatgaagtgt tatacaatca agaaatgggg 2400

 gcaagggcct gccccccact ccctcaccta cctccttagc attccttcag 2450

 gctgctactc ggggctccag gtgtgtgaat tggtcctcag atagtcaggc 2500

 ctgggtggag ggagtggcaa gtcaggcgtg cctcctacaa gcttcctaac 2550

 ctcttaagca tcatggaacc agtcagccct ctgtggagtc attgtgccgg 2600

 acctctgaaa agatctgcag gggccaagat gttgcagcca ccggaggctg 2650

 caaggatgtg ggttcttcca ggtgtgggcc cagcccccct ccttccagcc 2700

 tttgctcccc atcccacgtt ccactcgccc tgcctgttgt tcagtttgcg 2750

 tctcagtgct gactcacggg catgcttcat tgaggcccag gaagaggccc 2800

 tggtttgggg ctgtgccagc tcagagccct tgaaccagaa ccaactgctc 2850

 aggctcacaa aagttggcaa aatgcgggct gggcaggcag ctcggggcag 2900

 ggagcagcag tgcaggcctg gcctgtgtcc ccgtgcccag cgggctcccg 2950

 gagcagcatt ccagagcctc ctgcagagcc agcgaaggaa agctctagag 3000

 ggagacgact ccaccgcctc tctgctctga cccttctcag gcccgcctga 3050

 tgtgctggac catccccctg ctgccacggc ccctggctcc gcagtcaccc 3100

 tccatcagat gcttccagaa gcacctactc tgtgcaaggg cattcacaac 3150

 aggccagtgg gcaaacgtga gccagggcca gcggagaaac actaaagaag 3200

 actcggtggt tcagagcctg ggtctcagcg cgggacccgt ctggggtgaa 3250

 gaccttgggg ctgttgtgag tcggtggcag gaacgtgggc tctagactgt 3300

 gcattcaggc tctcctactt ggcagaatga tcttggggaa acgacttcat 3350

 ctgaacttca gatatttcac atgtgaagcg gggacaaaac catgcagctc 3400

 agaggtccct gtgggggctg ggggagctgc cctgcaggtc ttggcacatg 3450

 cacagcaggc tccccatagc tttgtcacca caaagggcac tgttctattc 3500

 acagcacctc ctgcttctgc ctggcaactg tgtctccctg tgctatattt 3550

 aattccacca gcaaagctgg cgaggcaggg cccagccctg aaggagatct 3600

 ccttgcctga cccctggacc tggaaatgga ggcttcatgt gcccgccttg 3650

 gcggcttaag cctgctgctt tggcagtgcc atgggtgagc cgagcagctg 3700

 tgaggtgggt ggggcagggc tgtagcccac gccgggtgct attccaggct 3750

 ctaggggctg gtgctcatcc ccacccccag cgacttccgt cctacctggc 3800

 atgctgcagc cctctgccgg ctgtggtgtc ctctgaattt ggacccaggt 3850

 tgcctgctct tgttgtgggg gtgggattgg ggctgtctgt gtttcccagg 3900

 tggagctcat gtttgtgatc ctctatctgg acagctctcc agaatcctgt 3950

 gttgcccctg ttctgccttt ctgggatggg agagaaggtg agggagccgg 4000

 cgagcaggtt ctaccctctc tgctaagggc ctagcacact ttgatgaggt 4050

 tcctggacgt gagaccctca caaagaccaa ccattcctct aatagccatt 4100

 taacggtact gcagttcatg ggaaaatgtc ctcattctta ggagatagat 4150

 gctggattat ataggtgaat gccttcaaga aatgtgtaat ttaattccaa 4200

 atagttcccc ccaaaataca caaagcaaat aaggccaaaa tgttcattgt 4250

 tgaatctgca gtggctggta tttcagtgaa cagtgtactt gttctttcaa 4300

 cttttctgta tgtttggaat ttttcttaat aaaagattgt gggaaatggt 4350

 catttgctga gcgcctccta gttgccaggc actggagggc gcatcaaaga 4400

 agagtcctac ccaggaggga gagcgcagct gctgcaggat tctcgcctgg 4450

 aagagtgggt ggctggctgg ctggctggaa ggggaggggc gagagggctg 4500

 tctcggtgat gagcacacgc gtgctggggt ggtttgggga gagggctgag 4550

 atttgtcacc agtgagccct tggcacggtc tctgctcccc accagggcag 4600

 cacgggacag aaacgtcacg gaggagtagc ctc 4633

<210> 3906
<211> 227
<212> PRT
<213> Homo sapien

<400> 3906
 Met Gly Gly Lys Gln Ser Thr Ala Ala Arg Ser Arg Gly Pro Phe
   1               5                  10                  15

 Pro Gly Val Ser Thr Asp Asp Ser Ala Val Pro Pro Pro Gly Gly
                  20                  25                  30

 Ala Pro His Phe Gly His Tyr Arg Thr Gly Gly Gly Ala Met Gly
                  35                  40                  45

 Leu Arg Ser Arg Ser Val Ser Ser Val Ala Gly Met Gly Met Asp
                  50                  55                  60

 Pro Ser Thr Ala Gly Gly Val Pro Phe Gly Leu Tyr Thr Pro Ala
                  65                  70                  75

 Ser Arg Gly Thr Gly Asp Ser Glu Arg Ala Pro Gly Gly Gly Gly
                  80                  85                  90

 Ser Ala Ser Asp Ser Thr Tyr Ala His Gly Asn Gly Tyr Gln Glu
                  95                 100                 105

 Thr Gly Gly Gly His His Arg Asp Gly Met Leu Tyr Leu Gly Ser
                 110                 115                 120

 Arg Ala Ser Leu Ala Asp Ala Leu Pro Leu His Ile Ala Pro Arg
                 125                 130                 135

 Trp Phe Ser Ser His Ser Gly Phe Lys Cys Pro Ile Cys Ser Lys
                 140                 145                 150

 Ser Val Ala Ser Asp Glu Met Glu Met His Phe Ile Met Cys Leu
                 155                 160                 165

 Ser Lys Pro Arg Leu Ser Tyr Asn Asp Asp Val Leu Thr Lys Asp
                 170                 175                 180

 Ala Gly Glu Cys Val Ile Cys Leu Glu Glu Leu Leu Gln Gly Asp
                 185                 190                 195

 Thr Ile Ala Arg Leu Pro Cys Leu Cys Ile Tyr His Lys Ser Cys
                 200                 205                 210

 Ile Asp Ser Trp Phe Glu Val Asn Arg Ser Cys Pro Glu His Pro
                 215                 220                 225

 Ala Asp


<210> 3907
<211> 4633
<212> DNA
<213> Homo sapien

<400> 3907
 gccctccatt gtctccacgg cggcgaggag cgccggcgag cgcagcccgg 50

 gaccgagcgg ggcggcgcgg ctggcggggc cggcggcggc tgaagcgaga 100

 gcgcgacgcg acgcgaccgc ggcttcccga gctgcgcctg gccgcccagc 150

 gccgcggccc gcccgaggcc tggaggggtc cgggccgccg tccatggtcg 200

 cggcgtcctg aggcggggga cgcgcccggc gcccccggcc ctcctccgcc 250

 tcctcccgcg gggcgggcgg cctcctccgg cgcctccccg cgcccgcccg 300

 ccgctcgccg ccgcctccct ccctccttcc ctgcggctcc cccggctttc 350

 ggagcccggg ggcggcctgt ggcgcgcgga gcccgcgccg gactgcgcct 400

 ctttggacct tgaggggaaa catgcgtttg ccttggatcg tttgaaattc 450

 tgagtttggg atccccgccc gcccgcctgc ctcttccgcc ccgcgggttt 500

 tttccttttt tccttttgct ttttttcctt ttctccctcc gggtctcctt 550

 tttgactccc tcccccttta tgctcgccca gccctccccc tgctgctgag 600

 aagtggggga gggtctcggc ctccaggttc ccgccccacc ggggcccggg 650

 cgagcatggg gggcaagcag agcacggcgg cccgctcccg gggccccttc 700

 ccgggggtct ccaccgatga cagcgccgtg ccgccgccgg gaggggcgcc 750

 ccatttcggg cactaccgga cgggcggcgg ggccatgggg ctgcgcagcc 800

 gctcggtcag ctcggtggca ggcatgggca tggaccccag cacggccggg 850

 ggggtgccct ttggcctcta cacccccgcc tcccggggca ccggcgactc 900

 cgagagggcg cccggcggcg gagggtctgc gtccgactcc acctatgccc 950

 atggcaatgg ttaccaggag acgggcggcg gtcaccatag agacgggatg 1000

 ctgtacctgg gctcccgagc ctcgctggcg gatgctctac ctctgcacat 1050

 cgcacccagg tggttcagct cgcatagtgg tttcaagtgc cccatttgct 1100

 ccaagtctgt ggcttctgac gagatggaaa tgcactttat aatgtgtttg 1150

 agcaaacctc gcctctccta caacgatgat gtgctgacta aagacgcggg 1200

 tgagtgtgtg atctgcctgg aggagctgct gcagggggac acgatagcca 1250

 ggctgccctg cctgtgcatc tatcacaaaa gctgcataga ctcgtggttt 1300

 gaagtgaaca gatcttgtcc ggaacaccct gcggactgac ctgcgggctt 1350

 gcttgctgac tcctctcaaa gggacagagc gcccctgctc cagggaggag 1400

 gctcaccgga ccctggggca gagctgagct tgggacacca gcgggaacag 1450

 ggcacccctt ctgcactgac ttccagatca tggttctccc ttcctccctg 1500

 aggacaccaa attggatgag agcaagtttg agagaagaat gaatcaactg 1550

 ctatccttcc cctcacccct cagcccagga gggaaagggc attttctttt 1600

 tcatctttga aaggcattgt gggtctgtct ttaaagtgtt tacaaaaaaa 1650

 aattatataa aaaaaaagtc tagtgtcgac tggtgttttc cctcgtgatg 1700

 tttacagctt gctgtttgct gcccagccat aacccactca gtgacagacg 1750

 aacacagcta aggcctcgct gccagccttc tgacggcggg cgagcacacg 1800

 gtctcttccc ctgccccaac tggccctctc caccaccaac ttctctactt 1850

 tgggtttgtt tggttttttc cctctatttt tctggctggt tttttgctct 1900

 tttctcccct tgagacccta atatcttgac ttcattgcca aaaaacaacc 1950

 cattgagaac tttcttccta ctgatcccat ctcttttccc ttctttcctc 2000

 ctggttccgg tcagttcaga ggatttaaca atcacaagtg tcctgcaaaa 2050

 atgcctgaac attattctta ggccctcgtg gatttttttt ttcagaaaac 2100

 ttaaacaaaa aaagacttac taagaaatat gtacagctac ccctgttttc 2150

 aggcactatg tttgagaaca ttttagccat tgatgttcac acgtggcatc 2200

 agcccatgca agataggttt ctgtatttat atattaaaat acaaaaaaaa 2250

 acttataaaa tgtttaaaaa aatgttcaaa gcttgggaga aaagctttct 2300

 tcattagtca aggtgttttg atatggtatt aaaatgtcta ataaaagatg 2350

 gcactgcgtg attttatttt aatgaagtgt tatacaatca agaaatgggg 2400

 gcaagggcct gccccccact ccctcaccta cctccttagc attccttcag 2450

 gctgctactc ggggctccag gtgtgtgaat tggtcctcag atagtcaggc 2500

 ctgggtggag ggagtggcaa gtcaggcgtg cctcctacaa gcttcctaac 2550

 ctcttaagca tcatggaacc agtcagccct ctgtggagtc attgtgccgg 2600

 acctctgaaa agatctgcag gggccaagat gttgcagcca ccggaggctg 2650

 caaggatgtg ggttcttcca ggtgtgggcc cagcccccct ccttccagcc 2700

 tttgctcccc atcccacgtt ccactcgccc tgcctgttgt tcagtttgcg 2750

 tctcagtgct gactcacggg catgcttcat tgaggcccag gaagaggccc 2800

 tggtttgggg ctgtgccagc tcagagccct tgaaccagaa ccaactgctc 2850

 aggctcacaa aagttggcaa aatgcgggct gggcaggcag ctcggggcag 2900

 ggagcagcag tgcaggcctg gcctgtgtcc ccgtgcccag cgggctcccg 2950

 gagcagcatt ccagagcctc ctgcagagcc agcgaaggaa agctctagag 3000

 ggagacgact ccaccgcctc tctgctctga cccttctcag gcccgcctga 3050

 tgtgctggac catccccctg ctgccacggc ccctggctcc gcagtcaccc 3100

 tccatcagat gcttccagaa gcacctactc tgtgcaaggg cattcacaac 3150

 aggccagtgg gcaaacgtga gccagggcca gcggagaaac actaaagaag 3200

 actcggtggt tcagagcctg ggtctcagcg cgggacccgt ctggggtgaa 3250

 gaccttgggg ctgttgtgag tcggtggcag gaacgtgggc tctagactgt 3300

 gcattcaggc tctcctactt ggcagaatga tcttggggaa acgacttcat 3350

 ctgaacttca gatatttcac atgtgaagcg gggacaaaac catgcagctc 3400

 agaggtccct gtgggggctg ggggagctgc cctgcaggtc ttggcacatg 3450

 cacagcaggc tccccatagc tttgtcacca caaagggcac tgttctattc 3500

 acagcacctc ctgcttctgc ctggcaactg tgtctccctg tgctatattt 3550

 aattccacca gcaaagctgg cgaggcaggg cccagccctg aaggagatct 3600

 ccttgcctga cccctggacc tggaaatgga ggcttcatgt gcccgccttg 3650

 gcggcttaag cctgctgctt tggcagtgcc atgggtgagc cgagcagctg 3700

 tgaggtgggt ggggcagggc tgtagcccac gccgggtgct attccaggct 3750

 ctaggggctg gtgctcatcc ccacccccag cgacttccgt cctacctggc 3800

 atgctgcagc cctctgccgg ctgtggtgtc ctctgaattt ggacccaggt 3850

 tgcctgctct tgttgtgggg gtgggattgg ggctgtctgt gtttcccagg 3900

 tggagctcat gtttgtgatc ctctatctgg acagctctcc agaatcctgt 3950

 gttgcccctg ttctgccttt ctgggatggg agagaaggtg agggagccgg 4000

 cgagcaggtt ctaccctctc tgctaagggc ctagcacact ttgatgaggt 4050

 tcctggacgt gagaccctca caaagaccaa ccattcctct aatagccatt 4100

 taacggtact gcagttcatg ggaaaatgtc ctcattctta ggagatagat 4150

 gctggattat ataggtgaat gccttcaaga aatgtgtaat ttaattccaa 4200

 atagttcccc ccaaaataca caaagcaaat aaggccaaaa tgttcattgt 4250

 tgaatctgca gtggctggta tttcagtgaa cagtgtactt gttctttcaa 4300

 cttttctgta tgtttggaat ttttcttaat aaaagattgt gggaaatggt 4350

 catttgctga gcgcctccta gttgccaggc actggagggc gcatcaaaga 4400

 agagtcctac ccaggaggga gagcgcagct gctgcaggat tctcgcctgg 4450

 aagagtgggt ggctggctgg ctggctggaa ggggaggggc gagagggctg 4500

 tctcggtgat gagcacacgc gtgctggggt ggtttgggga gagggctgag 4550

 atttgtcacc agtgagccct tggcacggtc tctgctcccc accagggcag 4600

 cacgggacag aaacgtcacg gaggagtagc ctc 4633

<210> 3908
<211> 227
<212> PRT
<213> Homo sapien

<400> 3908
 Met Gly Gly Lys Gln Ser Thr Ala Ala Arg Ser Arg Gly Pro Phe
   1               5                  10                  15

 Pro Gly Val Ser Thr Asp Asp Ser Ala Val Pro Pro Pro Gly Gly
                  20                  25                  30

 Ala Pro His Phe Gly His Tyr Arg Thr Gly Gly Gly Ala Met Gly
                  35                  40                  45

 Leu Arg Ser Arg Ser Val Ser Ser Val Ala Gly Met Gly Met Asp
                  50                  55                  60

 Pro Ser Thr Ala Gly Gly Val Pro Phe Gly Leu Tyr Thr Pro Ala
                  65                  70                  75

 Ser Arg Gly Thr Gly Asp Ser Glu Arg Ala Pro Gly Gly Gly Gly
                  80                  85                  90

 Ser Ala Ser Asp Ser Thr Tyr Ala His Gly Asn Gly Tyr Gln Glu
                  95                 100                 105

 Thr Gly Gly Gly His His Arg Asp Gly Met Leu Tyr Leu Gly Ser
                 110                 115                 120

 Arg Ala Ser Leu Ala Asp Ala Leu Pro Leu His Ile Ala Pro Arg
                 125                 130                 135

 Trp Phe Ser Ser His Ser Gly Phe Lys Cys Pro Ile Cys Ser Lys
                 140                 145                 150

 Ser Val Ala Ser Asp Glu Met Glu Met His Phe Ile Met Cys Leu
                 155                 160                 165

 Ser Lys Pro Arg Leu Ser Tyr Asn Asp Asp Val Leu Thr Lys Asp
                 170                 175                 180

 Ala Gly Glu Cys Val Ile Cys Leu Glu Glu Leu Leu Gln Gly Asp
                 185                 190                 195

 Thr Ile Ala Arg Leu Pro Cys Leu Cys Ile Tyr His Lys Ser Cys
                 200                 205                 210

 Ile Asp Ser Trp Phe Glu Val Asn Arg Ser Cys Pro Glu His Pro
                 215                 220                 225

 Ala Asp


<210> 3909
<211> 2291
<212> DNA
<213> Homo sapien

<400> 3909
 aaaaaggggc gggcgagcac ggcccgcggg cggcgttcgc tggagctggt 50

 ggaccgggcg gctgaccgag gggcggacgc gcggcggggc agaccgctgg 100

 ggactgcggg cggcgctgtg tccgtcgcca tgacagatca gacctattgt 150

 gaccgcctgg tgcaggacac gcctttcctg acaggccatg ggcgcttgag 200

 tgagcagcag gtggacagga tcatcctcca gctgaaccgt tactacccac 250

 agatccttac caacaaggag gcggaaaagt tccggaaccc caaggcatcc 300

 ttgcgtgtgc ggctctgtga cctcctgagc cacctgcagc ggagcggtga 350

 gcgggactgc caggagttct accgagccct gtatatccat gcccagcccc 400

 tgcacagccg cctgcccagc cgccacgctc tgcgtaagtt ccacatcacc 450

 aaccatgcat gcttggtgct ggcccgggga gggcacccca gcctgccgtt 500

 gatggcatgg atgtcctcca tgaccaccca agtctgctgc agcccaggcc 550

 tggcatcccc tctcgcctca gcccctcccc agaggccacc ctctggcccc 600

 gaggggagag tgtggcaggc acaggcagtg cagatgttgg tctctgtctc 650

 ccactttctc ccccttcctc cgtctctctc tcatggcagt tttcacacag 700

 catggggcat cttatacgtc cactcttgcc cttccttttc taacctcatt 750

 ccacggggat cccttcatgt ctgtgtggac agcaaccttg ttcccacagc 800

 tgcatggcgc tcctaggcgg tcccagctgg aattacccaa ccccatgacg 850

 gaccctttca ttgcagcgat ctgcacacgt gtgggtgttt ccataggaca 900

 ttgtcaggca cggatggctg gtccgaagca cgtgcatttc agttttgagg 950

 ctcctgtcct caggcagtgt ggactcaggc cctgggagtc atgtggatgc 1000

 cagtagcctg ggcccacaga gctgctggga tgtggggggc atatcaagtt 1050

 gaagatggca actctgatct gacgcctctg tgctcagggc ccctggagga 1100

 ggggctactg tcccttggcc cttagacaac aggacagaga ccagagggac 1150

 tgggcggctt gtcccaggct gctgggctgt ggtctctgac cccctggagg 1200

 cctccccacg cctcacagaa cacagtgcag acggtgggcg gggagagctc 1250

 gaggggaggc ccagccctgc aggtgggact ggctctccct ccccagccac 1300

 gagtatgcca cagggggctt tcaaaaccag gcagggccaa gccttggccc 1350

 cactggaggt agagcacctt ctgtggctcc cgggtgcctt taggcccgtc 1400

 caggagttgg agcagaggag aagacccaga ctgtgcatag ttccctgagg 1450

 agggctagcc tcaggtgcca cagcctggtt cggcctggcg gccccaggac 1500

 gcagcagcaa ccttgggctt cctgcggggt gactaccttg ccctccggcc 1550

 ctgcccgttg actaactatg ctctgtggtt ttgtttccag agaactcaga 1600

 ttgcacagag ctagactcgg gcagccagag cggcgagctg agtaacaggg 1650

 gtaacacctc cctgctgccc ctccctctct ctccctctct ctccctctct 1700

 ctttaccctc cccagggctc catctccgcc tcaggggctt ctccacccca 1750

 agtctggctc cattcctggc cttctgttgg tgacagaccc ccccctaagg 1800

 tgctcgtttg ggggctcttc aggcagcacc tcagcctggc acccccactc 1850

 ccctgcacag cccccaggcc tcaggacccc acccctctga ggcccagggg 1900

 agccctgttc acgctggttt ctccccagga cccatgagct tcctggctgg 1950

 cctgggcctt gctgtgggac tggccctgct cctgtactgc tatccgccag 2000

 accccaaggg cctgccaggg acccggcgcg tcctcggttt ctcgcctgtc 2050

 atcatcgaca gacatgtcag ccgctacctg ctggccttcc tggcagatga 2100

 cctagggggg ctctgacaga ccctggaccc agggcctcac ctgccactca 2150

 accaaagagt cctcgagccg gcccgccaag gggactgctg cttctttttc 2200

 taaatgcata tttttcatta tttataattt gtgtaaaaaa cacaccttca 2250

 ccttacaagg tgctgaccat attaaatgtt caagttctct c 2291

<210> 3910
<211> 228
<212> PRT
<213> Homo sapien

<400> 3910
 Met Thr Asp Gln Thr Tyr Cys Asp Arg Leu Val Gln Asp Thr Pro
   1               5                  10                  15

 Phe Leu Thr Gly His Gly Arg Leu Ser Glu Gln Gln Val Asp Arg
                  20                  25                  30

 Ile Ile Leu Gln Leu Asn Arg Tyr Tyr Pro Gln Ile Leu Thr Asn
                  35                  40                  45

 Lys Glu Ala Glu Lys Phe Arg Asn Pro Lys Ala Ser Leu Arg Val
                  50                  55                  60

 Arg Leu Cys Asp Leu Leu Ser His Leu Gln Arg Ser Gly Glu Arg
                  65                  70                  75

 Asp Cys Gln Glu Phe Tyr Arg Ala Leu Tyr Ile His Ala Gln Pro
                  80                  85                  90

 Leu His Ser Arg Leu Pro Ser Arg His Ala Leu Arg Lys Phe His
                  95                 100                 105

 Ile Thr Asn His Ala Cys Leu Val Leu Ala Arg Gly Gly His Pro
                 110                 115                 120

 Ser Leu Pro Leu Met Ala Trp Met Ser Ser Met Thr Thr Gln Val
                 125                 130                 135

 Cys Cys Ser Pro Gly Leu Ala Ser Pro Leu Ala Ser Ala Pro Pro
                 140                 145                 150

 Gln Arg Pro Pro Ser Gly Pro Glu Gly Arg Val Trp Gln Ala Gln
                 155                 160                 165

 Ala Val Gln Met Leu Val Ser Val Ser His Phe Leu Pro Leu Pro
                 170                 175                 180

 Pro Ser Leu Ser His Gly Ser Phe His Thr Ala Trp Gly Ile Leu
                 185                 190                 195

 Tyr Val His Ser Cys Pro Ser Phe Ser Asn Leu Ile Pro Arg Gly
                 200                 205                 210

 Ser Leu His Val Cys Val Asp Ser Asn Leu Val Pro Thr Ala Ala
                 215                 220                 225

 Trp Arg Ser


<210> 3911
<211> 3131
<212> DNA
<213> Homo sapien

<400> 3911
 atgatattga agagatggga gaagaagata gtgaggtcat tgaacctcct 50

 tctctacctc agcttcagac ccccctggcc agtgagctgg acctcatgcc 100

 ctacacaccc ccacagtcta ccccaaagtc tgccaaaggc agtgcaaaga 150

 aggaaggctc caaacggaaa atcaacatga gtggctacat cctgttcagc 200

 agtgagatga gggctgtgat taaggcccaa cacccagact actctttcgg 250

 ggagctcagc cgcctggtgg ggacagaatg gagaaatctt gagacagcca 300

 agaaagcaga atatgaaggc atgatgggtg gctatccgcc aggccttcca 350

 cctttgcagg gcccagttga tggccttgtt agcatgggca gcatgcagcc 400

 acttcaccct ggggggcctc caccccacca tcttccgcca ggtgtgcctg 450

 gcctcccggg catcccacca ccgggtgtga tgaaccaagg agtggcccct 500

 atggtaggga ctccagcacc aggtggaagt ccatatggac aacaggtggg 550

 agttttgggg cctccagggc agcaggcacc acctccatat cccggcccac 600

 atccagctgg accccctgtc atacagcagc caacaacacc catgtttgta 650

 gctcccccac caaagaccca gcggcttctt cactcagagg cctacctgaa 700

 atacattgaa ggactcagtg cggagtccaa cagcattagc aagtgggatc 750

 agacactggc agctcgaaga cgcgacgtcc atttgtcgaa agaacaggag 800

 agccgcctac cctctcactg gctgaaaagc aaaggggccc acaccaccat 850

 ggcagatgcc ctctggcgcc ttcgagattt gatgctccgg gacaccctca 900

 acattcgcca agcatacaac ctagaaaatg tttaatcaca ccattacgtt 950

 tcttttatat agaagcataa agagttgtgg atcagtagcc attttagtta 1000

 ctgggggtgg ggggaaggaa caaaggagga taatttttat tgcattttac 1050

 tgtacatcac aaggccattt ttatatacgg acacttttaa taagctattt 1100

 caatttgttt gttatattaa gttgacttta tcaaatacac aaagattttt 1150

 ttgcatatgt ttccttcgtt taaaaccagt ttcataattg gttgtatatg 1200

 tagacttgga gttttatctt tttacttgtt gccatggaac tgaaaccatt 1250

 agaggttttt gtcttggctt ggggtttttg ttttcttggt tttgggtttt 1300

 tttatatata tatataaaag aacaaaatga aaaaaaacac acacacacaa 1350

 gagtttacag attagtttaa attgataatg aaatgtgaag tttgtcctag 1400

 tttacatctt agagagggga gtatacttgt gtttgtttca tgtgcctgaa 1450

 tatcttaagc cactttctgc aaaagctgtt tcttacagat gaagtgcttt 1500

 ctttgaaagg tggttattta ggttttagat gtttaataga cacagcacat 1550

 ttgctctatt aactcagagg ctcactacag aaatatgtaa tcagtgctgt 1600

 gcatctgtct gcagctaatg tacctcctgg acaccaggag gggaaaaagc 1650

 actttttcaa ttgtgctgag ttagacatct gtgagttaga ctatggtgtc 1700

 agtgattttt gcagaacacg tgcacaaccc tgaggtatgt ttaatctagg 1750

 caggtacgtt taaggatatt ttgatctatt tataatgaat tcacaattta 1800

 tgcctataaa tttcagatga tttaaaattt taaacctgtt acattgaaaa 1850

 acattgaagt tcgtcttgaa gaaagcatta aggtatgcat ggaggtgatt 1900

 tatttttaaa cataacacct aacctaacat gggtaagaga gtatggaact 1950

 agatatgagc tgtataagaa gcataattgt gaacaagtag attgattgcc 2000

 ttcatataca agtatgtttt agtattcctt atttccttat tatcagatgt 2050

 attttttctt ttaagtttca atgttgttat aattctcaac cagaaattta 2100

 atactttcta aaatattttt taaatttagc ttgtgctttt gaattacagg 2150

 agaagggaat cataatttaa taaaacgctt actagaaaga ccattacaga 2200

 tcccaaacac ttgggtttgg tgaccctgtc tttcttatat gaccctacaa 2250

 taaacatttg aaggcagcat aggatggcag acagtaggaa cattgtttca 2300

 cttggcggca tgtttttgaa acctgcttta tagtaactgg gtgattgcca 2350

 ttgtggtaga gcttccactg ctgtttataa tctgagagag ttaatctcag 2400

 aggatgcttt tttcctttta atctgctatg aatcagtacc cagatgttta 2450

 attactgtac ttattaaatc atgagggcaa aagagtgtag aatggaaaaa 2500

 agtctcttgt atctagatac tttaaatatg ggaggccctt taacttaatt 2550

 gcctttagtc aaccactgga tttgaatttg catcaagtat tttaaataat 2600

 attgaattta aaaaaatgta ttgcagtagt gtgtcagtac cttattgtta 2650

 aagtgagtca gataaatctt caattcctgg ctatttgggc aattgaatca 2700

 tcatggactg tataatgcaa tcagattatt ttgtttctag acatccttga 2750

 attacaccaa agaacatgaa atttagttgt ggttaaatta tttatttatt 2800

 tcatgcattc attttatttc ccttaaggtc tggatgagac ttctttgggg 2850

 agcctctaaa aaaatttttc actgggggcc acgtgggtca ttagaagcca 2900

 gagctctcct ccaggctcct tcccagtgcc tagaggtgct ataggaaaca 2950

 tagatccagc caggggcttc cctaaagcag tgcagcaccg gcccagggca 3000

 tcactagaca ggccctaatt aagttttttt taaaaagcct gtgtatttat 3050

 tttagaatca tgtttttctg tatattaact tgggggatat cgttaatatt 3100

 taggatataa gatttgaggt cagccatctt c 3131

<210> 3912
<211> 306
<212> PRT
<213> Homo sapien

<400> 3912
 Met Gly Glu Glu Asp Ser Glu Val Ile Glu Pro Pro Ser Leu Pro
   1               5                  10                  15

 Gln Leu Gln Thr Pro Leu Ala Ser Glu Leu Asp Leu Met Pro Tyr
                  20                  25                  30

 Thr Pro Pro Gln Ser Thr Pro Lys Ser Ala Lys Gly Ser Ala Lys
                  35                  40                  45

 Lys Glu Gly Ser Lys Arg Lys Ile Asn Met Ser Gly Tyr Ile Leu
                  50                  55                  60

 Phe Ser Ser Glu Met Arg Ala Val Ile Lys Ala Gln His Pro Asp
                  65                  70                  75

 Tyr Ser Phe Gly Glu Leu Ser Arg Leu Val Gly Thr Glu Trp Arg
                  80                  85                  90

 Asn Leu Glu Thr Ala Lys Lys Ala Glu Tyr Glu Gly Met Met Gly
                  95                 100                 105

 Gly Tyr Pro Pro Gly Leu Pro Pro Leu Gln Gly Pro Val Asp Gly
                 110                 115                 120

 Leu Val Ser Met Gly Ser Met Gln Pro Leu His Pro Gly Gly Pro
                 125                 130                 135

 Pro Pro His His Leu Pro Pro Gly Val Pro Gly Leu Pro Gly Ile
                 140                 145                 150

 Pro Pro Pro Gly Val Met Asn Gln Gly Val Ala Pro Met Val Gly
                 155                 160                 165

 Thr Pro Ala Pro Gly Gly Ser Pro Tyr Gly Gln Gln Val Gly Val
                 170                 175                 180

 Leu Gly Pro Pro Gly Gln Gln Ala Pro Pro Pro Tyr Pro Gly Pro
                 185                 190                 195

 His Pro Ala Gly Pro Pro Val Ile Gln Gln Pro Thr Thr Pro Met
                 200                 205                 210

 Phe Val Ala Pro Pro Pro Lys Thr Gln Arg Leu Leu His Ser Glu
                 215                 220                 225

 Ala Tyr Leu Lys Tyr Ile Glu Gly Leu Ser Ala Glu Ser Asn Ser
                 230                 235                 240

 Ile Ser Lys Trp Asp Gln Thr Leu Ala Ala Arg Arg Arg Asp Val
                 245                 250                 255

 His Leu Ser Lys Glu Gln Glu Ser Arg Leu Pro Ser His Trp Leu
                 260                 265                 270

 Lys Ser Lys Gly Ala His Thr Thr Met Ala Asp Ala Leu Trp Arg
                 275                 280                 285

 Leu Arg Asp Leu Met Leu Arg Asp Thr Leu Asn Ile Arg Gln Ala
                 290                 295                 300

 Tyr Asn Leu Glu Asn Val
                 305

<210> 3913
<211> 2883
<212> DNA
<213> Homo sapien

<400> 3913
 aacagatctt catgaatgtc gctatctttg aggatgaagt ttttgctgga 50

 gttaccacac accaggaact ctttccacac agcctgctga gtgtgattgc 100

 caacttcatc cctttctctg atctcaacca gagtccacgg aacatgtacc 150

 aatgccagat gggtaagcaa actatgggct ttccacttct cacttatcaa 200

 gaccgatcgg ataacaaact gtatcgtctt cagactcctc agagtccctt 250

 ggtgagaccc tccatgtatg attattatga catggataac tatccaattg 300

 ggaccaatgc catcgttgct gtgatttctt acactggcta tgatatggaa 350

 gatgccatga ttgtgaataa ggcctcttgg gaacgaggct ttgcccatgg 400

 aagtgtctac aagtctgagt tcatagacct ctctgaaaaa attaaacaag 450

 gagatagtag cctggtgttt ggcatcaaac ctggtgaccc acgcgttctg 500

 cagaagttag atgacgatgg attgccgttt ataggagcaa aactgcagta 550

 cggagatccg tattacagct acctcaacct caacaccggg gaaagttttg 600

 tgatgtacta taagagtaaa gaaaattgtg ttgtggataa catcaaagtg 650

 tgcagtaatg acactgggag tggaaaattc aagtgtgttt gcatcactat 700

 gagagtgcct cggaacccaa ctatcggaga taaatttgcc agtcgccatg 750

 ggcagaaggg cattttaagc agattgtggc cggctgagga catgcctttt 800

 actgagagtg ggatggtccc agacattctg ttcaatcccc atggttttcc 850

 atcccgcatg accattggga tgttaattga gagtatggcc gggaagtctg 900

 cagctttgca tggtctctgc catgatgcta cacccttcat cttctcagag 950

 gagaactcgg ccttagaata ctttggtgag atgttaaagg ctgctggcta 1000

 caatttctat ggcaccgaga ggttatatag tggcatcagt gggctagaac 1050

 tggaagcaga catcttcata ggagtggttt attatcagcg cttacgccat 1100

 atggtctcag acaaatttca agtaaggaca actggagccc gagacagagt 1150

 caccaaccag cctattgggg gaagaaatgt ccagggtgga atccgttttg 1200

 gggagatgga acgggatgcg cttttagctc atggtacatc ttttctcctt 1250

 catgaccgcc tcttcaactg ctcagatcgg tcggtagccc atgtgtgtga 1300

 agtgtggcag tttactctct ccactgttgg agaagccacc cccttcttgg 1350

 tctgccatgc gcaacagaaa atacaactgt actctgtgta gtcgcagtga 1400

 cactatcgat actgtttctg tgccttatgt ttttcggtat tttgtagctg 1450

 aactggcagc tatgaacatc aaagtgaaac tggatgttgt ttaacttgat 1500

 gttgaccttt tggattaagg ggactatcag attaaagcaa aatgtaattt 1550

 taattcaatg aagatatcat taccaggtta ctcttgagat ttttcaacgg 1600

 tgttagaact ctcaaccaag acctgaaaac caagtatgca aggtttctga 1650

 atctctctgg tagattaact attgacaatg attttctgtt atctttgttc 1700

 aaaaagttca tgtcttctca aaatatgaaa tattgataaa tggaagagca 1750

 tacggtgaca agtctccttt ccaaccccag gttccctaca ccctgctctc 1800

 agcaggcagt gagtgtcaca cacctgttaa tccatcttga gcaggacagt 1850

 actatacaaa tagaatgcaa gctgtaatgt aattttatat tttcttatag 1900

 ccacgttgaa gtaaaaacaa acaggtacag tgttttttac cagctttata 1950

 gaagtacagt tgttacatat ttaatgaata caatttgatg ggtctgacta 2000

 tatgcacaca cctttgatac catcaccaca atcagggtaa taaacatacc 2050

 tgtcatctcc acaagtttcc tcctgcccct ttgttttttg ctttttggtt 2100

 gctgttgagt ttttgttttg tcttctgtgg taagaacact taactcaaga 2150

 cctaccctct taacaaatct ttaagtgcac gatatagtat tgttaattcc 2200

 aggcaccatg ttgtacaaca gatctttaga ccttacttgt cttgcataac 2250

 tgaagcttta tacctgttga acaactctcc atttccctgg cccctagcaa 2300

 ccacccttct accctgtttc tatgagtttg actattacag atatctcata 2350

 tagtgggatc atgcaatatt tgtcctgtga ctggcttatt tcacttagca 2400

 tagtgaaata agattcatcc attttggaag ccaggcatgg tgctgtgcat 2450

 ctatagtccc tgctatttga gaggctgagg tgggaggatc atttgagtgc 2500

 aggagttcaa ggacagcctg ggtaatatag gaagaccctg tcttgaagac 2550

 cctgacctca agtgatccac ccacctcggc ctccgaaagt gctaggatta 2600

 caggtgtgag ccactgtgcc tggcctccgg tgagtatttt atatttagtc 2650

 tacacttcca tacttggctt ttttctgctt ttatgttgat ctgctttcat 2700

 agcagtgtgt agagtgccac ttatgttttc tttcttgtgt acagtatttt 2750

 attgtatgga tttaccatcc cctgtgtatt taagttgttc cattctttgg 2800

 ccattataac ttttttctgc aaatattctg gtgacttatc tttggccatt 2850

 ataaactgtt gataataaaa aaaaaaaaaa aaa 2883

<210> 3914
<211> 459
<212> PRT
<213> Homo sapien

<400> 3914
 Met Asn Val Ala Ile Phe Glu Asp Glu Val Phe Ala Gly Val Thr
   1               5                  10                  15

 Thr His Gln Glu Leu Phe Pro His Ser Leu Leu Ser Val Ile Ala
                  20                  25                  30

 Asn Phe Ile Pro Phe Ser Asp Leu Asn Gln Ser Pro Arg Asn Met
                  35                  40                  45

 Tyr Gln Cys Gln Met Gly Lys Gln Thr Met Gly Phe Pro Leu Leu
                  50                  55                  60

 Thr Tyr Gln Asp Arg Ser Asp Asn Lys Leu Tyr Arg Leu Gln Thr
                  65                  70                  75

 Pro Gln Ser Pro Leu Val Arg Pro Ser Met Tyr Asp Tyr Tyr Asp
                  80                  85                  90

 Met Asp Asn Tyr Pro Ile Gly Thr Asn Ala Ile Val Ala Val Ile
                  95                 100                 105

 Ser Tyr Thr Gly Tyr Asp Met Glu Asp Ala Met Ile Val Asn Lys
                 110                 115                 120

 Ala Ser Trp Glu Arg Gly Phe Ala His Gly Ser Val Tyr Lys Ser
                 125                 130                 135

 Glu Phe Ile Asp Leu Ser Glu Lys Ile Lys Gln Gly Asp Ser Ser
                 140                 145                 150

 Leu Val Phe Gly Ile Lys Pro Gly Asp Pro Arg Val Leu Gln Lys
                 155                 160                 165

 Leu Asp Asp Asp Gly Leu Pro Phe Ile Gly Ala Lys Leu Gln Tyr
                 170                 175                 180

 Gly Asp Pro Tyr Tyr Ser Tyr Leu Asn Leu Asn Thr Gly Glu Ser
                 185                 190                 195

 Phe Val Met Tyr Tyr Lys Ser Lys Glu Asn Cys Val Val Asp Asn
                 200                 205                 210

 Ile Lys Val Cys Ser Asn Asp Thr Gly Ser Gly Lys Phe Lys Cys
                 215                 220                 225

 Val Cys Ile Thr Met Arg Val Pro Arg Asn Pro Thr Ile Gly Asp
                 230                 235                 240

 Lys Phe Ala Ser Arg His Gly Gln Lys Gly Ile Leu Ser Arg Leu
                 245                 250                 255

 Trp Pro Ala Glu Asp Met Pro Phe Thr Glu Ser Gly Met Val Pro
                 260                 265                 270

 Asp Ile Leu Phe Asn Pro His Gly Phe Pro Ser Arg Met Thr Ile
                 275                 280                 285

 Gly Met Leu Ile Glu Ser Met Ala Gly Lys Ser Ala Ala Leu His
                 290                 295                 300

 Gly Leu Cys His Asp Ala Thr Pro Phe Ile Phe Ser Glu Glu Asn
                 305                 310                 315

 Ser Ala Leu Glu Tyr Phe Gly Glu Met Leu Lys Ala Ala Gly Tyr
                 320                 325                 330

 Asn Phe Tyr Gly Thr Glu Arg Leu Tyr Ser Gly Ile Ser Gly Leu
                 335                 340                 345

 Glu Leu Glu Ala Asp Ile Phe Ile Gly Val Val Tyr Tyr Gln Arg
                 350                 355                 360

 Leu Arg His Met Val Ser Asp Lys Phe Gln Val Arg Thr Thr Gly
                 365                 370                 375

 Ala Arg Asp Arg Val Thr Asn Gln Pro Ile Gly Gly Arg Asn Val
                 380                 385                 390

 Gln Gly Gly Ile Arg Phe Gly Glu Met Glu Arg Asp Ala Leu Leu
                 395                 400                 405

 Ala His Gly Thr Ser Phe Leu Leu His Asp Arg Leu Phe Asn Cys
                 410                 415                 420

 Ser Asp Arg Ser Val Ala His Val Cys Glu Val Trp Gln Phe Thr
                 425                 430                 435

 Leu Ser Thr Val Gly Glu Ala Thr Pro Phe Leu Val Cys His Ala
                 440                 445                 450

 Gln Gln Lys Ile Gln Leu Tyr Ser Val
                 455

<210> 3915
<211> 3014
<212> DNA
<213> Homo sapien

<400> 3915
 agcggagttc tcccgggcgc ctagcgggat cgccagcgcg gcagtggggg 50

 cttccgcggc tgcaagccag cgggtcctgt gagggcgagc ggaggcggag 100

 aaagggcgcg ggagtgagag agggtgagtc agccactgtc tatgcaataa 150

 agggaggcct caccgcggga tagggctgaa ttcagaagtg cggcccgtgc 200

 cgcagtctgt tccaggacgc ggcttgtctt agcgtcagcg agggaaggtt 250

 gaggaggagc cagagcctgg tcctgcagcc tttctcgccg tcagcgcccg 300

 tcgccatctc caccatgcag tcccgggaag acgtcccgcg ctctcgccgc 350

 ctcgccagtc cccgtggtgg gaggcggccc aagaggattt ccaagccctc 400

 ggtttcggcc tttttcacgg gtccagagga gttaaaggac acggcccatt 450

 ctgcagccct gctggcacag ctcaagtcct tctacgacgc gcggctgctg 500

 tgtgatgtga ccatcgaggt ggtgacgcct ggcagcgggc ctggcacggg 550

 tcgcctcttt tcctgcaatc gcaacgtgct agcagctgcg tgtccctact 600

 tcaagagcat gttcacaggt ggcatgtacg agagccagca ggccagcgtg 650

 accatgcacg atgtggacgc cgagtccttc gaggtgttgg tcgactactg 700

 ctacacgggt cgtgtgtctc tcagtgaggc caatgtgcag cgcctgtacg 750

 cggcctccga catgctacag ctggaatatg tgcgggaagc ctgtgcctcc 800

 ttcttagccc gacgtcttga cctgaccaac tgcaccgcca tcctcaagtt 850

 tgcagacgcc ttcgaccatc acaagcttcg atctcaggcc cagtcctaca 900

 tagctcacaa cttcaagcag ctcagccgaa tgggttcaat tcgggaggag 950

 actctagcag atctaaccct ggcccagctg ctggctgtcc tacgcctgga 1000

 tagtctggac atagagagtg agcggactgt atgccatgta gctgtgcagt 1050

 ggctggaggc tgctgccaaa gagcggggtc ccagtgctgc agaagtcttc 1100

 aagtgcgtgc gctggatgca cttcactgaa gaagatcagg actacttaga 1150

 agggctgctg accaagccca tcgtgaagaa gtactgcctg gacgttattg 1200

 aaggggccct gcagatgcgc tatggtgacc tgttgtacaa gtctctggtg 1250

 ccagtgccaa acagcagcag cagcagtagc agcagcaact ctcttgtatc 1300

 tgcagcagaa aatccacccc agagactggg tatgtgtgcc aaggagatgg 1350

 tgatcttctt tggacatcct agagatccct ttctctgcta tgacccttac 1400

 tcgggggaca tttacacaat gccatcccct ttgaccagct ttgctcacac 1450

 taagactgtc acctcctcag ctgtctgtgt gtccccagac catgacatct 1500

 atctagctgc tcagcccagg aaagacctct gggtgtataa accagctcag 1550

 aatagttggc agcaacttgc agatcgcttg ctgtgtcgtg agggcatgga 1600

 tgtggcatat ctcaatggct acatctacat tttgggggga cgagacccta 1650

 ttactggagt taagttgaag gaagtggaat gctacagtgt tcagagaaac 1700

 cagtgggcat tggtggctcc tgtccctcat tccttctatt cctttgaact 1750

 catagtggtt cagaactatc tttatgctgt caacagtaag cgcatgcttt 1800

 gctatgatcc tagccacaat atgtggctga actgtgcttc tcttaaacgt 1850

 agtgactttc aggaagcatg tgtcttcaat gatgaaatct attgtatctg 1900

 tgacatccca gtcatgaagg tctacaaccc agctagggga gaatggaggc 1950

 ggattagtaa tattcctttg gattcagaga cccacaacta ccagattgtc 2000

 aatcatgacc aaaagttgct tctcatcact tctacaaccc cacaatggaa 2050

 aaagaaccga gtgacagtgt atgagtatga tactagggaa gatcagtgga 2100

 ttaatatagg taccatgtta ggccttttgc agtttgactc tggctttatt 2150

 tgcctttgtg ctcgtgttta tccttcctgc cttgaacctg gtcagagttt 2200

 tattactgag gaagatgatg cacggagtga gtctagtact gaatgggact 2250

 tagatggatt cagtgagctg gactctgagt caggaagttc aagttctttt 2300

 tcagatgatg aagtctgggt gcaagtagca cctcagcgaa atgcacagga 2350

 tcagcagggt tctttgtaaa tagtattttg agacactaag atgtttctac 2400

 tgctacggaa tgtattttaa acacatatcg tttctttttc ttggaaaaaa 2450

 agttgattag gaccacagat ttggtttaga aagggtaata ttttgaaata 2500

 ctacaaggtt tagacagtcc atgaaatcga cctgtttaat aatttaccat 2550

 cctgaaagtc cagaattaaa atatggaagc aagaactata taattgatta 2600

 ggatgcttgg taggtttttt tcattgttca aatattcatt gcacagtgga 2650

 ttgttttgat tagttagtat gctttttttt taattaattc agtcttctgt 2700

 taatttttaa gttttggtta gtgccacaag gaatttaact ttttgatttg 2750

 tataatagaa aactgaacta ggaattgtta gcggggtttt gaaggatgtg 2800

 tactttcctt caaaataaag tggtagattt tcaaaatttt acactagtca 2850

 gttctttata ttctaagtta aatgtagttt gtaaaattat tttggttttc 2900

 ttctacaaag gaaaaaattg gatttatata tataaggtta ctgcataatg 2950

 atttcatttt gataatgtgc agaatggcct cataagctca cagaaagcaa 3000

 aaaaaaaaaa aaaa 3014

<210> 3916
<211> 684
<212> PRT
<213> Homo sapien

<400> 3916
 Met Gln Ser Arg Glu Asp Val Pro Arg Ser Arg Arg Leu Ala Ser
   1               5                  10                  15

 Pro Arg Gly Gly Arg Arg Pro Lys Arg Ile Ser Lys Pro Ser Val
                  20                  25                  30

 Ser Ala Phe Phe Thr Gly Pro Glu Glu Leu Lys Asp Thr Ala His
                  35                  40                  45

 Ser Ala Ala Leu Leu Ala Gln Leu Lys Ser Phe Tyr Asp Ala Arg
                  50                  55                  60

 Leu Leu Cys Asp Val Thr Ile Glu Val Val Thr Pro Gly Ser Gly
                  65                  70                  75

 Pro Gly Thr Gly Arg Leu Phe Ser Cys Asn Arg Asn Val Leu Ala
                  80                  85                  90

 Ala Ala Cys Pro Tyr Phe Lys Ser Met Phe Thr Gly Gly Met Tyr
                  95                 100                 105

 Glu Ser Gln Gln Ala Ser Val Thr Met His Asp Val Asp Ala Glu
                 110                 115                 120

 Ser Phe Glu Val Leu Val Asp Tyr Cys Tyr Thr Gly Arg Val Ser
                 125                 130                 135

 Leu Ser Glu Ala Asn Val Gln Arg Leu Tyr Ala Ala Ser Asp Met
                 140                 145                 150

 Leu Gln Leu Glu Tyr Val Arg Glu Ala Cys Ala Ser Phe Leu Ala
                 155                 160                 165

 Arg Arg Leu Asp Leu Thr Asn Cys Thr Ala Ile Leu Lys Phe Ala
                 170                 175                 180

 Asp Ala Phe Asp His His Lys Leu Arg Ser Gln Ala Gln Ser Tyr
                 185                 190                 195

 Ile Ala His Asn Phe Lys Gln Leu Ser Arg Met Gly Ser Ile Arg
                 200                 205                 210

 Glu Glu Thr Leu Ala Asp Leu Thr Leu Ala Gln Leu Leu Ala Val
                 215                 220                 225

 Leu Arg Leu Asp Ser Leu Asp Ile Glu Ser Glu Arg Thr Val Cys
                 230                 235                 240

 His Val Ala Val Gln Trp Leu Glu Ala Ala Ala Lys Glu Arg Gly
                 245                 250                 255

 Pro Ser Ala Ala Glu Val Phe Lys Cys Val Arg Trp Met His Phe
                 260                 265                 270

 Thr Glu Glu Asp Gln Asp Tyr Leu Glu Gly Leu Leu Thr Lys Pro
                 275                 280                 285

 Ile Val Lys Lys Tyr Cys Leu Asp Val Ile Glu Gly Ala Leu Gln
                 290                 295                 300

 Met Arg Tyr Gly Asp Leu Leu Tyr Lys Ser Leu Val Pro Val Pro
                 305                 310                 315

 Asn Ser Ser Ser Ser Ser Ser Ser Ser Asn Ser Leu Val Ser Ala
                 320                 325                 330

 Ala Glu Asn Pro Pro Gln Arg Leu Gly Met Cys Ala Lys Glu Met
                 335                 340                 345

 Val Ile Phe Phe Gly His Pro Arg Asp Pro Phe Leu Cys Tyr Asp
                 350                 355                 360

 Pro Tyr Ser Gly Asp Ile Tyr Thr Met Pro Ser Pro Leu Thr Ser
                 365                 370                 375

 Phe Ala His Thr Lys Thr Val Thr Ser Ser Ala Val Cys Val Ser
                 380                 385                 390

 Pro Asp His Asp Ile Tyr Leu Ala Ala Gln Pro Arg Lys Asp Leu
                 395                 400                 405

 Trp Val Tyr Lys Pro Ala Gln Asn Ser Trp Gln Gln Leu Ala Asp
                 410                 415                 420

 Arg Leu Leu Cys Arg Glu Gly Met Asp Val Ala Tyr Leu Asn Gly
                 425                 430                 435

 Tyr Ile Tyr Ile Leu Gly Gly Arg Asp Pro Ile Thr Gly Val Lys
                 440                 445                 450

 Leu Lys Glu Val Glu Cys Tyr Ser Val Gln Arg Asn Gln Trp Ala
                 455                 460                 465

 Leu Val Ala Pro Val Pro His Ser Phe Tyr Ser Phe Glu Leu Ile
                 470                 475                 480

 Val Val Gln Asn Tyr Leu Tyr Ala Val Asn Ser Lys Arg Met Leu
                 485                 490                 495

 Cys Tyr Asp Pro Ser His Asn Met Trp Leu Asn Cys Ala Ser Leu
                 500                 505                 510

 Lys Arg Ser Asp Phe Gln Glu Ala Cys Val Phe Asn Asp Glu Ile
                 515                 520                 525

 Tyr Cys Ile Cys Asp Ile Pro Val Met Lys Val Tyr Asn Pro Ala
                 530                 535                 540

 Arg Gly Glu Trp Arg Arg Ile Ser Asn Ile Pro Leu Asp Ser Glu
                 545                 550                 555

 Thr His Asn Tyr Gln Ile Val Asn His Asp Gln Lys Leu Leu Leu
                 560                 565                 570

 Ile Thr Ser Thr Thr Pro Gln Trp Lys Lys Asn Arg Val Thr Val
                 575                 580                 585

 Tyr Glu Tyr Asp Thr Arg Glu Asp Gln Trp Ile Asn Ile Gly Thr
                 590                 595                 600

 Met Leu Gly Leu Leu Gln Phe Asp Ser Gly Phe Ile Cys Leu Cys
                 605                 610                 615

 Ala Arg Val Tyr Pro Ser Cys Leu Glu Pro Gly Gln Ser Phe Ile
                 620                 625                 630

 Thr Glu Glu Asp Asp Ala Arg Ser Glu Ser Ser Thr Glu Trp Asp
                 635                 640                 645

 Leu Asp Gly Phe Ser Glu Leu Asp Ser Glu Ser Gly Ser Ser Ser
                 650                 655                 660

 Ser Phe Ser Asp Asp Glu Val Trp Val Gln Val Ala Pro Gln Arg
                 665                 670                 675

 Asn Ala Gln Asp Gln Gln Gly Ser Leu
                 680

<210> 3917
<211> 1598
<212> DNA
<213> Homo sapien

<400> 3917
 agctgcggcg ctgggctggc ggcggcgagt ccacgtgctc cccgcggccg 50

 gttgaaaccg ttggcgggcg ctggctgaga ggcaatgttt gctgtcttcc 100

 attggagtga ctgaatttct acatgacggc tttttgacaa gacttaaaac 150

 ctgtcttgga tagagaatat ttagccattt acctaaaaat ggtatttttt 200

 acatgcaatg catgtggtga atcagtgaag aaaatacaag tggaaaagca 250

 tgtgtctgtt tgcagaaact gtgaatgcct ttcttgcatt gactgcggta 300

 aagatttctg gggcgatgac tataaaaacc acgtgaaatg cataagtgaa 350

 gatcagaagt atggtggcaa aggctatgaa ggtaaaaccc acaaaggcga 400

 catcaaacag caggcgtgga ttcagaaaat tagtgaatta ataaagagac 450

 ccaatgtcag ccccaaagtg agagaacttt tagagcaaat tagtgctttt 500

 gacaacgttc ccaggaaaaa ggcaaaattt cagaattgga tgaagaacag 550

 tttaaaagtt cataatgaat ccattctgga ccaggtgtgg aatatctttt 600

 ctgaagcttc caacagcgaa ccagtcaata aggaacagga tcaacggcca 650

 ctccacccag tggcaaatcc acatgcagaa atctccacca aggttccagc 700

 ctccaaagtg aaagacgccg tggaacagca aggggaggtg aagaagaata 750

 aaagagaaag aaaggaagaa cggcagaaga aaaggaaaag agaaaagaaa 800

 gaactaaagt tagaaaacca ccaggaaaac tcaaggaatc agaagcctaa 850

 gaagcgcaaa aagggacagg aggctgacct tgaggctggt ggggaggaag 900

 tccctgaggc caatggctct gcagggaaga ggagcaagaa gaagaagcag 950

 cgcaaggaca gcgccagtga ggaagaggca cgcgtgggcg cagggaagag 1000

 gaagcggagg cactcggaag ttgaaacaga ttctaagaag aaaaagatga 1050

 agctcccaga gcatcctgag ggcggagaac cagaagacga tgaggctcct 1100

 gcaaaaggta aattcaactg gaagggaact attaaagcaa ttctgaaaca 1150

 ggccccagac aatgaaataa ccatcaaaaa gctaaggaaa aaggttttag 1200

 ctcagtacta cacagtgaca gatgagcatc acagatccga agaggaactc 1250

 ctggtcatct ttaacaagaa aatcagcaag aaccctacct ttaagttatt 1300

 aaaggacaaa gtcaagcttg tgaaatgaac atttgtgtat ttaaaaattg 1350

 aatccattct gctgacttct tcctttcact gctgtttata aaatgtgtaa 1400

 tgaattctaa caactcaaat tttgcttttt gaagctgtat ttttaagtta 1450

 agaaaatata tttttggtat aacttttatg agaaaaataa aatatattct 1500

 ggtccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1598

<210> 3918
<211> 379
<212> PRT
<213> Homo sapien

<400> 3918
 Met Val Phe Phe Thr Cys Asn Ala Cys Gly Glu Ser Val Lys Lys
   1               5                  10                  15

 Ile Gln Val Glu Lys His Val Ser Val Cys Arg Asn Cys Glu Cys
                  20                  25                  30

 Leu Ser Cys Ile Asp Cys Gly Lys Asp Phe Trp Gly Asp Asp Tyr
                  35                  40                  45

 Lys Asn His Val Lys Cys Ile Ser Glu Asp Gln Lys Tyr Gly Gly
                  50                  55                  60

 Lys Gly Tyr Glu Gly Lys Thr His Lys Gly Asp Ile Lys Gln Gln
                  65                  70                  75

 Ala Trp Ile Gln Lys Ile Ser Glu Leu Ile Lys Arg Pro Asn Val
                  80                  85                  90

 Ser Pro Lys Val Arg Glu Leu Leu Glu Gln Ile Ser Ala Phe Asp
                  95                 100                 105

 Asn Val Pro Arg Lys Lys Ala Lys Phe Gln Asn Trp Met Lys Asn
                 110                 115                 120

 Ser Leu Lys Val His Asn Glu Ser Ile Leu Asp Gln Val Trp Asn
                 125                 130                 135

 Ile Phe Ser Glu Ala Ser Asn Ser Glu Pro Val Asn Lys Glu Gln
                 140                 145                 150

 Asp Gln Arg Pro Leu His Pro Val Ala Asn Pro His Ala Glu Ile
                 155                 160                 165

 Ser Thr Lys Val Pro Ala Ser Lys Val Lys Asp Ala Val Glu Gln
                 170                 175                 180

 Gln Gly Glu Val Lys Lys Asn Lys Arg Glu Arg Lys Glu Glu Arg
                 185                 190                 195

 Gln Lys Lys Arg Lys Arg Glu Lys Lys Glu Leu Lys Leu Glu Asn
                 200                 205                 210

 His Gln Glu Asn Ser Arg Asn Gln Lys Pro Lys Lys Arg Lys Lys
                 215                 220                 225

 Gly Gln Glu Ala Asp Leu Glu Ala Gly Gly Glu Glu Val Pro Glu
                 230                 235                 240

 Ala Asn Gly Ser Ala Gly Lys Arg Ser Lys Lys Lys Lys Gln Arg
                 245                 250                 255

 Lys Asp Ser Ala Ser Glu Glu Glu Ala Arg Val Gly Ala Gly Lys
                 260                 265                 270

 Arg Lys Arg Arg His Ser Glu Val Glu Thr Asp Ser Lys Lys Lys
                 275                 280                 285

 Lys Met Lys Leu Pro Glu His Pro Glu Gly Gly Glu Pro Glu Asp
                 290                 295                 300

 Asp Glu Ala Pro Ala Lys Gly Lys Phe Asn Trp Lys Gly Thr Ile
                 305                 310                 315

 Lys Ala Ile Leu Lys Gln Ala Pro Asp Asn Glu Ile Thr Ile Lys
                 320                 325                 330

 Lys Leu Arg Lys Lys Val Leu Ala Gln Tyr Tyr Thr Val Thr Asp
                 335                 340                 345

 Glu His His Arg Ser Glu Glu Glu Leu Leu Val Ile Phe Asn Lys
                 350                 355                 360

 Lys Ile Ser Lys Asn Pro Thr Phe Lys Leu Leu Lys Asp Lys Val
                 365                 370                 375

 Lys Leu Val Lys


<210> 3919
<211> 1598
<212> DNA
<213> Homo sapien

<400> 3919
 agctgcggcg ctgggctggc ggcggcgagt ccacgtgctc cccgcggccg 50

 gttgaaaccg ttggcgggcg ctggctgaga ggcaatgttt gctgtcttcc 100

 attggagtga ctgaatttct acatgacggc tttttgacaa gacttaaaac 150

 ctgtcttgga tagagaatat ttagccattt acctaaaaat ggtatttttt 200

 acatgcaatg catgtggtga atcagtgaag aaaatacaag tggaaaagca 250

 tgtgtctgtt tgcagaaact gtgaatgcct ttcttgcatt gactgcggta 300

 aagatttctg gggcgatgac tataaaaacc acgtgaaatg cataagtgaa 350

 gatcagaagt atggtggcaa aggctatgaa ggtaaaaccc acaaaggcga 400

 catcaaacag caggcgtgga ttcagaaaat tagtgaatta ataaagagac 450

 ccaatgtcag ccccaaagtg agagaacttt tagagcaaat tagtgctttt 500

 gacaacgttc ccaggaaaaa ggcaaaattt cagaattgga tgaagaacag 550

 tttaaaagtt cataatgaat ccattctgga ccaggtgtgg aatatctttt 600

 ctgaagcttc caacagcgaa ccagtcaata aggaacagga tcaacggcca 650

 ctccacccag tggcaaatcc acatgcagaa atctccacca aggttccagc 700

 ctccaaagtg aaagacgccg tggaacagca aggggaggtg aagaagaata 750

 aaagagaaag aaaggaagaa cggcagaaga aaaggaaaag agaaaagaaa 800

 gaactaaagt tagaaaacca ccaggaaaac tcaaggaatc agaagcctaa 850

 gaagcgcaaa aagggacagg aggctgacct tgaggctggt ggggaggaag 900

 tccctgaggc caatggctct gcagggaaga ggagcaagaa gaagaagcag 950

 cgcaaggaca gcgccagtga ggaagaggca cgcgtgggcg cagggaagag 1000

 gaagcggagg cactcggaag ttgaaacaga ttctaagaag aaaaagatga 1050

 agctcccaga gcatcctgag ggcggagaac cagaagacga tgaggctcct 1100

 gcaaaaggta aattcaactg gaagggaact attaaagcaa ttctgaaaca 1150

 ggccccagac aatgaaataa ccatcaaaaa gctaaggaaa aaggttttag 1200

 ctcagtacta cacagtgaca gatgagcatc acagatccga agaggaactc 1250

 ctggtcatct ttaacaagaa aatcagcaag aaccctacct ttaagttatt 1300

 aaaggacaaa gtcaagcttg tgaaatgaac atttgtgtat ttaaaaattg 1350

 aatccattct gctgacttct tcctttcact gctgtttata aaatgtgtaa 1400

 tgaattctaa caactcaaat tttgcttttt gaagctgtat ttttaagtta 1450

 agaaaatata tttttggtat aacttttatg agaaaaataa aatatattct 1500

 ggtccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1598

<210> 3920
<211> 379
<212> PRT
<213> Homo sapien

<400> 3920
 Met Val Phe Phe Thr Cys Asn Ala Cys Gly Glu Ser Val Lys Lys
   1               5                  10                  15

 Ile Gln Val Glu Lys His Val Ser Val Cys Arg Asn Cys Glu Cys
                  20                  25                  30

 Leu Ser Cys Ile Asp Cys Gly Lys Asp Phe Trp Gly Asp Asp Tyr
                  35                  40                  45

 Lys Asn His Val Lys Cys Ile Ser Glu Asp Gln Lys Tyr Gly Gly
                  50                  55                  60

 Lys Gly Tyr Glu Gly Lys Thr His Lys Gly Asp Ile Lys Gln Gln
                  65                  70                  75

 Ala Trp Ile Gln Lys Ile Ser Glu Leu Ile Lys Arg Pro Asn Val
                  80                  85                  90

 Ser Pro Lys Val Arg Glu Leu Leu Glu Gln Ile Ser Ala Phe Asp
                  95                 100                 105

 Asn Val Pro Arg Lys Lys Ala Lys Phe Gln Asn Trp Met Lys Asn
                 110                 115                 120

 Ser Leu Lys Val His Asn Glu Ser Ile Leu Asp Gln Val Trp Asn
                 125                 130                 135

 Ile Phe Ser Glu Ala Ser Asn Ser Glu Pro Val Asn Lys Glu Gln
                 140                 145                 150

 Asp Gln Arg Pro Leu His Pro Val Ala Asn Pro His Ala Glu Ile
                 155                 160                 165

 Ser Thr Lys Val Pro Ala Ser Lys Val Lys Asp Ala Val Glu Gln
                 170                 175                 180

 Gln Gly Glu Val Lys Lys Asn Lys Arg Glu Arg Lys Glu Glu Arg
                 185                 190                 195

 Gln Lys Lys Arg Lys Arg Glu Lys Lys Glu Leu Lys Leu Glu Asn
                 200                 205                 210

 His Gln Glu Asn Ser Arg Asn Gln Lys Pro Lys Lys Arg Lys Lys
                 215                 220                 225

 Gly Gln Glu Ala Asp Leu Glu Ala Gly Gly Glu Glu Val Pro Glu
                 230                 235                 240

 Ala Asn Gly Ser Ala Gly Lys Arg Ser Lys Lys Lys Lys Gln Arg
                 245                 250                 255

 Lys Asp Ser Ala Ser Glu Glu Glu Ala Arg Val Gly Ala Gly Lys
                 260                 265                 270

 Arg Lys Arg Arg His Ser Glu Val Glu Thr Asp Ser Lys Lys Lys
                 275                 280                 285

 Lys Met Lys Leu Pro Glu His Pro Glu Gly Gly Glu Pro Glu Asp
                 290                 295                 300

 Asp Glu Ala Pro Ala Lys Gly Lys Phe Asn Trp Lys Gly Thr Ile
                 305                 310                 315

 Lys Ala Ile Leu Lys Gln Ala Pro Asp Asn Glu Ile Thr Ile Lys
                 320                 325                 330

 Lys Leu Arg Lys Lys Val Leu Ala Gln Tyr Tyr Thr Val Thr Asp
                 335                 340                 345

 Glu His His Arg Ser Glu Glu Glu Leu Leu Val Ile Phe Asn Lys
                 350                 355                 360

 Lys Ile Ser Lys Asn Pro Thr Phe Lys Leu Leu Lys Asp Lys Val
                 365                 370                 375

 Lys Leu Val Lys


<210> 3921
<211> 2952
<212> DNA
<213> Homo sapien

<400> 3921
 cagtttcatt aggctctgaa gccattacaa aggttgctta acttctaatt 50

 atttgatcac tgaggaaaat ccagaaagct acacaacact gaaggggtga 100

 aataaaagtc cagcgatcca gcgaaagaaa agagaagtga cagaaacaac 150

 tttacctgga ctgaagataa aagcacagac aagagaacaa tgccctggac 200

 atggctccag agatccacat gacaggccca atgtgcctca ttgagaacac 250

 taatggggaa ctggtggcga atccagaagc tctgaaaatc ctgtctgcca 300

 ttacacagcc tgtggtggtg gtggcaattg tgggcctcta ccgcacagga 350

 aaatcctacc tgatgaacaa gctagctggg aagaataagg gcttctctct 400

 gggctccaca gtgaaatctc acaccaaagg aatctggatg tggtgtgtgc 450

 ctcaccccaa aaagccagaa cacaccttag tcctgcttga cactgagggc 500

 ctgggagatg taaagaaggg tgacaaccag aatgactcct ggatcttcac 550

 cctggccgtc ctcctgagca gcactctcgt gtacaatagc atgggaacca 600

 tcaaccagca ggctatggac caactgtact atgtgacaga gctgacacat 650

 cgaatccgat caaaatcctc acctgatgag aatgagaatg aggattcagc 700

 tgactttgtg agcttcttcc cagattttgt gtggacactg agagatttct 750

 ccctggactt ggaagcagat ggacaacccc tcacaccaga tgagtacctg 800

 gagtattccc tgaagctaac gcaaggtaac aggaagcttg cccagcttga 850

 gaaactacaa gatgaagagc tggaccctga atttgtgcaa caagtagcag 900

 acttctgttc ctacatcttt agcaattcca aaactaaaac tctttcagga 950

 ggcatcaagg tcaatgggcc ttgtctagag agcctagtgc tgacctatat 1000

 caatgctatc agcagagggg atctgccctg catggagaac gcagtcctgg 1050

 ccttggccca gatagagaac tcagccgcag tgcaaaaggc tattgcccac 1100

 tatgaccagc agatgggcca gaaggtgcag ctgcccgcag aaaccctcca 1150

 ggagctgctg gacctgcaca gggttagtga gagggaggcc actgaagtct 1200

 atatgaagaa ctctttcaag gatgtggacc atctgtttca aaagaaatta 1250

 gcggcccagc tagacaaaaa gcgggatgac ttttgtaaac agaatcaaga 1300

 agcatcatca gatcgttgct cagctttact tcaggtcatt ttcagtcctc 1350

 tagaagaaga agtgaaggcg ggaatttatt cgaaaccagg gggctattgt 1400

 ctctttattc agaagctaca agacctggag aaaaagtact atgaggaacc 1450

 aaggaagggg atacaggctg aagagattct gcagacatac ttgaaatcca 1500

 aggagtctgt gaccgatgca attctacaga cagaccagat tctcacagaa 1550

 aaggaaaagg agattgaagt ggaatgtgta aaagctgaat ctgcacaggc 1600

 ttcagcaaaa atggtggagg aaatgcaaat aaagtatcag cagatgatgg 1650

 aagagaaaga gaagagttat caagaacatg tgaaacaatt gactgagaag 1700

 atggagaggg agagggccca gttgctggaa gagcaagaga agaccctcac 1750

 tagtaaactt caggaacagg cccgagtact aaaggagaga tgccaaggtg 1800

 aaagtaccca acttcaaaat gagatacaaa agctacagaa gaccctgaaa 1850

 aaaaaaacca agagatatat gtcgcataag ctaaagatct aaacaacaga 1900

 gcttttctgt catcctaacc caaggcataa ctgaaacaat tttagaattt 1950

 ggaacaagtg tcactatatt tgataataat tagatcttgc atcataacac 2000

 taaaagttta caagaacatg cagttcaatg atcaaaatca tgttttttcc 2050

 ttaaaaagat tgtaaattgt gcaacaaaga tgcatttacc tctgtaccaa 2100

 cagaggaggg atcatgagtt gccaccactc agaagtttat tcttccagac 2150

 gaccagtgga tactgaggaa agtcttaggt aaaaatcttg ggacatattt 2200

 gggcactggt ttggccaagt gtacaatagg tcccaatatc agaaacaacc 2250

 atcctagctt cctagggaag acagtgtaca gttctccatt atatcaaggc 2300

 tacaaggtct atgagcaata atgtgatttc tggacattgc ccatggataa 2350

 ttctcactga tggatctcaa gctaaagcaa accatcttat acagagatct 2400

 agaatcttat attttccata ggaaggtaaa gaaatcatta gcaagagtag 2450

 gaattgaatc ataaacaaat tggctaatga agaaatcttt tctttcttgt 2500

 tcaattcatc tagattataa ccttaatgtg acacctgaga cctttagaca 2550

 gttgaccctg aattaaatag tcacatggta acaattatgc actgtgtaat 2600

 tttagtaatg tataacatgc aatgatgcac tttaactgaa gatagagact 2650

 atgttagaaa attgaactaa tttaattatt tgattgtttt aatcctaaag 2700

 cataagttag tcttttcctg attcttaaag gtcatacttg aaatcctgcc 2750

 aattttcccc aaagggaata tggaattttt tttgactttc ttttgagcaa 2800

 taaaataatt gtcttgccat tacttagtat atgtagactt catcccaatt 2850

 gtcaaacatc ctaggtaagt ggttgacatt tcttacagca attacagatt 2900

 atttttgaac tagaaataaa ctaaactaga aacaaaaaaa aaaaaaaaaa 2950

 aa 2952

<210> 3922
<211> 563
<212> PRT
<213> Homo sapien

<400> 3922
 Met Ala Pro Glu Ile His Met Thr Gly Pro Met Cys Leu Ile Glu
   1               5                  10                  15

 Asn Thr Asn Gly Glu Leu Val Ala Asn Pro Glu Ala Leu Lys Ile
                  20                  25                  30

 Leu Ser Ala Ile Thr Gln Pro Val Val Val Val Ala Ile Val Gly
                  35                  40                  45

 Leu Tyr Arg Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly
                  50                  55                  60

 Lys Asn Lys Gly Phe Ser Leu Gly Ser Thr Val Lys Ser His Thr
                  65                  70                  75

 Lys Gly Ile Trp Met Trp Cys Val Pro His Pro Lys Lys Pro Glu
                  80                  85                  90

 His Thr Leu Val Leu Leu Asp Thr Glu Gly Leu Gly Asp Val Lys
                  95                 100                 105

 Lys Gly Asp Asn Gln Asn Asp Ser Trp Ile Phe Thr Leu Ala Val
                 110                 115                 120

 Leu Leu Ser Ser Thr Leu Val Tyr Asn Ser Met Gly Thr Ile Asn
                 125                 130                 135

 Gln Gln Ala Met Asp Gln Leu Tyr Tyr Val Thr Glu Leu Thr His
                 140                 145                 150

 Arg Ile Arg Ser Lys Ser Ser Pro Asp Glu Asn Glu Asn Glu Asp
                 155                 160                 165

 Ser Ala Asp Phe Val Ser Phe Phe Pro Asp Phe Val Trp Thr Leu
                 170                 175                 180

 Arg Asp Phe Ser Leu Asp Leu Glu Ala Asp Gly Gln Pro Leu Thr
                 185                 190                 195

 Pro Asp Glu Tyr Leu Glu Tyr Ser Leu Lys Leu Thr Gln Gly Asn
                 200                 205                 210

 Arg Lys Leu Ala Gln Leu Glu Lys Leu Gln Asp Glu Glu Leu Asp
                 215                 220                 225

 Pro Glu Phe Val Gln Gln Val Ala Asp Phe Cys Ser Tyr Ile Phe
                 230                 235                 240

 Ser Asn Ser Lys Thr Lys Thr Leu Ser Gly Gly Ile Lys Val Asn
                 245                 250                 255

 Gly Pro Cys Leu Glu Ser Leu Val Leu Thr Tyr Ile Asn Ala Ile
                 260                 265                 270

 Ser Arg Gly Asp Leu Pro Cys Met Glu Asn Ala Val Leu Ala Leu
                 275                 280                 285

 Ala Gln Ile Glu Asn Ser Ala Ala Val Gln Lys Ala Ile Ala His
                 290                 295                 300

 Tyr Asp Gln Gln Met Gly Gln Lys Val Gln Leu Pro Ala Glu Thr
                 305                 310                 315

 Leu Gln Glu Leu Leu Asp Leu His Arg Val Ser Glu Arg Glu Ala
                 320                 325                 330

 Thr Glu Val Tyr Met Lys Asn Ser Phe Lys Asp Val Asp His Leu
                 335                 340                 345

 Phe Gln Lys Lys Leu Ala Ala Gln Leu Asp Lys Lys Arg Asp Asp
                 350                 355                 360

 Phe Cys Lys Gln Asn Gln Glu Ala Ser Ser Asp Arg Cys Ser Ala
                 365                 370                 375

 Leu Leu Gln Val Ile Phe Ser Pro Leu Glu Glu Glu Val Lys Ala
                 380                 385                 390

 Gly Ile Tyr Ser Lys Pro Gly Gly Tyr Cys Leu Phe Ile Gln Lys
                 395                 400                 405

 Leu Gln Asp Leu Glu Lys Lys Tyr Tyr Glu Glu Pro Arg Lys Gly
                 410                 415                 420

 Ile Gln Ala Glu Glu Ile Leu Gln Thr Tyr Leu Lys Ser Lys Glu
                 425                 430                 435

 Ser Val Thr Asp Ala Ile Leu Gln Thr Asp Gln Ile Leu Thr Glu
                 440                 445                 450

 Lys Glu Lys Glu Ile Glu Val Glu Cys Val Lys Ala Glu Ser Ala
                 455                 460                 465

 Gln Ala Ser Ala Lys Met Val Glu Glu Met Gln Ile Lys Tyr Gln
                 470                 475                 480

 Gln Met Met Glu Glu Lys Glu Lys Ser Tyr Gln Glu His Val Lys
                 485                 490                 495

 Gln Leu Thr Glu Lys Met Glu Arg Glu Arg Ala Gln Leu Leu Glu
                 500                 505                 510

 Glu Gln Glu Lys Thr Leu Thr Ser Lys Leu Gln Glu Gln Ala Arg
                 515                 520                 525

 Val Leu Lys Glu Arg Cys Gln Gly Glu Ser Thr Gln Leu Gln Asn
                 530                 535                 540

 Glu Ile Gln Lys Leu Gln Lys Thr Leu Lys Lys Lys Thr Lys Arg
                 545                 550                 555

 Tyr Met Ser His Lys Leu Lys Ile
                 560

<210> 3923
<211> 689
<212> DNA
<213> Homo sapien

<400> 3923
 gcaagagagc gggaagccga gctgggcgag aagtagggga gggcggtgct 50

 ccgccgcggt ggcggttgct atcgcttcgc agaacctact caggcagcca 100

 gctgagaaga gttgagggaa agtgctgctg ctgggtctgc agacgcgatg 150

 gataacgtgc agccgaaaat aaaacatcgc cccttctgct tcagtgtgaa 200

 aggccacgtg aagatgctgc ggctggcact aactgtgaca tctatgacct 250

 tttttatcat cgcacaagcc cctgaaccat atattgttat cactggattt 300

 gaagtcaccg ttatcttatt tttcatactt ttatatgtac tcagacttga 350

 tcgattaatg aagtggttat tttggccttt gcttgatatt atcaactcac 400

 tggtaacaac agtattcatg ctcatcgtat ctgtgttggc actgatacca 450

 gaaaccacaa cattgacagt tggtggaggg gtgtttgcac ttgtgacagc 500

 agtatgctgt cttgccgacg gggcccttat ttaccggaag cttctgttca 550

 atcccagcgg tccttaccag aaaaagcctg tgcatgaaaa aaaagaagtt 600

 ttgtaatttt atattacttt ttagtttgat actaagtatt aaacatattt 650

 ctgtattctt ccaaaaaaaa aaaaaaaaaa aaaaaaaaa 689

<210> 3924
<211> 152
<212> PRT
<213> Homo sapien

<400> 3924
 Met Asp Asn Val Gln Pro Lys Ile Lys His Arg Pro Phe Cys Phe
   1               5                  10                  15

 Ser Val Lys Gly His Val Lys Met Leu Arg Leu Ala Leu Thr Val
                  20                  25                  30

 Thr Ser Met Thr Phe Phe Ile Ile Ala Gln Ala Pro Glu Pro Tyr
                  35                  40                  45

 Ile Val Ile Thr Gly Phe Glu Val Thr Val Ile Leu Phe Phe Ile
                  50                  55                  60

 Leu Leu Tyr Val Leu Arg Leu Asp Arg Leu Met Lys Trp Leu Phe
                  65                  70                  75

 Trp Pro Leu Leu Asp Ile Ile Asn Ser Leu Val Thr Thr Val Phe
                  80                  85                  90

 Met Leu Ile Val Ser Val Leu Ala Leu Ile Pro Glu Thr Thr Thr
                  95                 100                 105

 Leu Thr Val Gly Gly Gly Val Phe Ala Leu Val Thr Ala Val Cys
                 110                 115                 120

 Cys Leu Ala Asp Gly Ala Leu Ile Tyr Arg Lys Leu Leu Phe Asn
                 125                 130                 135

 Pro Ser Gly Pro Tyr Gln Lys Lys Pro Val His Glu Lys Lys Glu
                 140                 145                 150

 Val Leu


<210> 3925
<211> 2435
<212> DNA
<213> Homo sapien

<400> 3925
 tagaaagaat gatcgacttg ctgtttccaa gatgttgaat aagtttacta 50

 aatctggtct caagtcacag tttgcttact gcatgctgat ccgaattgcc 100

 agtcgcttac taaaagaaac tgaggatggc catgaaagtc cactgtttga 150

 tttcattgag agctgcttgc gaaataaaca tgaaatggtt atttatgaag 200

 ctgcttcagc tatcatccat cttcctaact gcactgcaag agagttggca 250

 cctgctgttt cagttcttca acttttctgt agttctccta agccagcctt 300

 gagatatgca gctgtgagga ccttgaacaa ggtggcaatg aagcacccct 350

 ctgctgttac tgcctgcaat ctggacttag aaaacttaat cacagactca 400

 aacagaagca ttgctacctt agccattact acactcctca aaacaggaag 450

 tgagagcagt gtggaccggc tcatgaagca gatatcttct tttgtgtctg 500

 aaatctcaga tgagttcaag gtggtggttg tacaggcaat tagtgctctc 550

 tgtcagaaat accctcgaaa gcacagtgtc atgatgactt tcctctccaa 600

 catgctccga gatgatggag gctttgagta caagcgggcc attgtggact 650

 gtataatcag cattgtggaa gagaaccctg agagtaaaga agcaggccta 700

 gcccaccttt gtgaattcat tgaggactgt gaacacactg ttctggctac 750

 taagattcta cacttgttgg gcaaagaggg ccctagaacg cctgtcccct 800

 ccaaatatat ccgttttatt tttaataggg ttgtcctgga gaatgaggct 850

 gtcagagctg ctgctgtgag tgctttggct aaatttgggg ctcagaatga 900

 gagtcttctc ccaagcatcc ttgtactctt acagaggtgt atgatggata 950

 ctgatgacga ggtacgagac agagctacct tctatctgaa tgtgctgcag 1000

 cagaggcaga tggcactaaa tgccacatat atctttaatg gtttgacagt 1050

 ctctgtacca gggatggaaa aagccttaca ccagtacacg ttggagcctt 1100

 cagaaaaacc gtttgacatg aaatcaattc ctcttgctat ggctcctgtc 1150

 tttgaacaga aagcagaaat cacacttgtg gctactaagc cagagaagtt 1200

 ggctccttcc aggcaagaca ttttccaaga acaattggct gccattcctg 1250

 ggtttctgaa tataggaccc ttgttcaagt cttctgagcc tgttcaactt 1300

 acagaagcag agacagaata ttttgttcga tgtatcaagc acatgtttac 1350

 caatcacatc gtgttccagt ttgactgcac caacactctc aatgaccagc 1400

 tgctggaaaa agtgacagtg cagatggagc catcagattc ctatgaagtg 1450

 ctgtcttgta tcccagcccc cagccttcct taaaaccaac caggaatatg 1500

 ttacactctt gttcgtttgc ctgatgatga ccctacagca gttgcaggct 1550

 cctttagctg caccatgaag tttacagtcc gggactgtga ccctaacact 1600

 ggagttccag atgaggatgg gtatgatgat gagtatgtgc tggaagatct 1650

 cgaagtgact gtgtctgacc atattcagaa agtactgaag cctaactttg 1700

 ctgctgcttg ggaagaggtg ggagatacct ttgagaaaga ggaaaccttt 1750

 gccctcagtt ctaccaaaac ccttgaagag gctgtcaaca atatcatcac 1800

 atttctgggc atgcagccat gtgagaggtc cgataaagta cctgagaaca 1850

 agaattccca ttcgctctat ctggcaggta tattcagagg tggctatgat 1900

 ttattggtga ggtccaggct ggccttagcc gatggagtga ccatgcaggt 1950

 gactgtcaga agtaaagaga gaacacctgt agatgttatc ttagcttctg 2000

 ttggataaat gcttactgga caagaggaaa ctgatgcaca ctacatggtc 2050

 agtgggcttt taggctagtg gcatcagttt cccagaatca gacttttgaa 2100

 gatgaatgac tttggagaag caaattaaac atttggccct gagccagcag 2150

 atcaagcaaa tgtctatctt tgcgcatggg ttgttttttt tttttttctt 2200

 tttattctac ttggtcagct ttgggacgat agtgcagctt tgggtgatct 2250

 tgaaaatcaa atactatcct atactccagc tgcttaactt cattttattc 2300

 tttaatgtgt acctgaaagc tcctggcaat gctggaaaat ttttatccca 2350

 gaggggtagg ggggagggga agccagagtc cacttttgtc acaattcatt 2400

 tttattaata gaaaataaac acttattcca gtttc 2435

<210> 3926
<211> 483
<212> PRT
<213> Homo sapien

<400> 3926
 Met Leu Asn Lys Phe Thr Lys Ser Gly Leu Lys Ser Gln Phe Ala
   1               5                  10                  15

 Tyr Cys Met Leu Ile Arg Ile Ala Ser Arg Leu Leu Lys Glu Thr
                  20                  25                  30

 Glu Asp Gly His Glu Ser Pro Leu Phe Asp Phe Ile Glu Ser Cys
                  35                  40                  45

 Leu Arg Asn Lys His Glu Met Val Ile Tyr Glu Ala Ala Ser Ala
                  50                  55                  60

 Ile Ile His Leu Pro Asn Cys Thr Ala Arg Glu Leu Ala Pro Ala
                  65                  70                  75

 Val Ser Val Leu Gln Leu Phe Cys Ser Ser Pro Lys Pro Ala Leu
                  80                  85                  90

 Arg Tyr Ala Ala Val Arg Thr Leu Asn Lys Val Ala Met Lys His
                  95                 100                 105

 Pro Ser Ala Val Thr Ala Cys Asn Leu Asp Leu Glu Asn Leu Ile
                 110                 115                 120

 Thr Asp Ser Asn Arg Ser Ile Ala Thr Leu Ala Ile Thr Thr Leu
                 125                 130                 135

 Leu Lys Thr Gly Ser Glu Ser Ser Val Asp Arg Leu Met Lys Gln
                 140                 145                 150

 Ile Ser Ser Phe Val Ser Glu Ile Ser Asp Glu Phe Lys Val Val
                 155                 160                 165

 Val Val Gln Ala Ile Ser Ala Leu Cys Gln Lys Tyr Pro Arg Lys
                 170                 175                 180

 His Ser Val Met Met Thr Phe Leu Ser Asn Met Leu Arg Asp Asp
                 185                 190                 195

 Gly Gly Phe Glu Tyr Lys Arg Ala Ile Val Asp Cys Ile Ile Ser
                 200                 205                 210

 Ile Val Glu Glu Asn Pro Glu Ser Lys Glu Ala Gly Leu Ala His
                 215                 220                 225

 Leu Cys Glu Phe Ile Glu Asp Cys Glu His Thr Val Leu Ala Thr
                 230                 235                 240

 Lys Ile Leu His Leu Leu Gly Lys Glu Gly Pro Arg Thr Pro Val
                 245                 250                 255

 Pro Ser Lys Tyr Ile Arg Phe Ile Phe Asn Arg Val Val Leu Glu
                 260                 265                 270

 Asn Glu Ala Val Arg Ala Ala Ala Val Ser Ala Leu Ala Lys Phe
                 275                 280                 285

 Gly Ala Gln Asn Glu Ser Leu Leu Pro Ser Ile Leu Val Leu Leu
                 290                 295                 300

 Gln Arg Cys Met Met Asp Thr Asp Asp Glu Val Arg Asp Arg Ala
                 305                 310                 315

 Thr Phe Tyr Leu Asn Val Leu Gln Gln Arg Gln Met Ala Leu Asn
                 320                 325                 330

 Ala Thr Tyr Ile Phe Asn Gly Leu Thr Val Ser Val Pro Gly Met
                 335                 340                 345

 Glu Lys Ala Leu His Gln Tyr Thr Leu Glu Pro Ser Glu Lys Pro
                 350                 355                 360

 Phe Asp Met Lys Ser Ile Pro Leu Ala Met Ala Pro Val Phe Glu
                 365                 370                 375

 Gln Lys Ala Glu Ile Thr Leu Val Ala Thr Lys Pro Glu Lys Leu
                 380                 385                 390

 Ala Pro Ser Arg Gln Asp Ile Phe Gln Glu Gln Leu Ala Ala Ile
                 395                 400                 405

 Pro Gly Phe Leu Asn Ile Gly Pro Leu Phe Lys Ser Ser Glu Pro
                 410                 415                 420

 Val Gln Leu Thr Glu Ala Glu Thr Glu Tyr Phe Val Arg Cys Ile
                 425                 430                 435

 Lys His Met Phe Thr Asn His Ile Val Phe Gln Phe Asp Cys Thr
                 440                 445                 450

 Asn Thr Leu Asn Asp Gln Leu Leu Glu Lys Val Thr Val Gln Met
                 455                 460                 465

 Glu Pro Ser Asp Ser Tyr Glu Val Leu Ser Cys Ile Pro Ala Pro
                 470                 475                 480

 Ser Leu Pro


<210> 3927
<211> 2865
<212> DNA
<213> Homo sapien

<400> 3927
 attgctggcc taggtgaaac tgacggtctc cattagaaac atggctgcga 50

 ccagtctagt gggtatttgt agaagagcct cagcgttcct gaaggcagct 100

 tgttccctag taaatcccaa ggacgctgct cactcgggtt gcaggtcttc 150

 tcttagtttg ttgcctaaga gtacaccaaa tgtgacatcc tttcaccaat 200

 atagattact tcataccaca ttgtcaagga aaggactaga agaatttttt 250

 gatgacccaa aaaactgggg gcaagaaaaa gtaaaatctg gagcagcatg 300

 gacctgtcag caactaagga acaaaagtaa tgaagattta cacaaacttt 350

 ggtatgtctt actgaaagaa agaaacatgc ttctaaccct agagcaggag 400

 gccaagcggc agagattgcc aatgccaagt ccagagcggt tagataaggt 450

 agtagattcc atggatgcat tagataaagt tgtccaggaa agagaagatg 500

 ccctaaggct tcttcagact ggtcaagaaa gagctagacc tggtgcttgg 550

 agaagagaca tctttggaag aatcatctgg cacaagttca agcagtgggt 600

 tataccttgg cacctaaata aaagatacaa taggaaacga ttctttgcct 650

 tgccttatgt ggaccatttt ctcagactgg aacgtgagaa acgagcccgc 700

 atcaaagcac ggaaggaaaa tttagagaga aagaaagcaa aaattctttt 750

 aaaaaagttt ccacatcttg ctgaagccca aaagtcaagt cttgtctaag 800

 atgtctgaac tattaaattt accattttgt ttttcttgaa tagtctgtgt 850

 acaggagtaa atatgttaag tggtttataa agaaattctg tttttagtca 900

 agtgacttta ctaatcagtt gttctaagtg tgaatatggc atgctaatta 950

 gctaatttgg tagaagctaa tttgcttcta aaaatcaggt ataaagttca 1000

 gatgagattc ccactttata aattctgaca tttaagcagg ctttaaatgt 1050

 cacctgctac cttagagtgt gaaggtgatg gtaactgcca cagcaaaggc 1100

 aataccgtag tttttgaatt tgaataatag ttttacctct gttgttaata 1150

 ggctatgaag aggatgtggg tattgctgtt aataaacgga ggactttgat 1200

 tcaaaataat gagaaataca tttagtcctt aaagtagtaa tcacagtgca 1250

 caacagtcca aaatatattt ctggaatggc taatttttat ttaattctgt 1300

 aagcctaagg taaaaagcat aggcagtaac ttttactagt caataaaaag 1350

 cagttctacc aatccactgg taattaatac actaaacaga gttggaaagc 1400

 attttactga aagcaaaata tttagagaaa atagacattt atacaaaatt 1450

 ataaaatgct tgtaataaga ataagtgcat ttcaaggaaa gcacaaactt 1500

 aatttataga gccagttaaa gctttaaaaa atttaagtgg aaattgaaat 1550

 atgcaaaaat gtataaacat tctacaaaag atggtcattc ttttcctgag 1600

 tatactaaag ctatgaaacg taaggtgaca aaaggaaggt agaagcttgg 1650

 gaactctttc tcaagggcat tttctttcta cacactgctt ccctccttct 1700

 tcatattctt gcttggaaat ccacatccca acacttgtgg tgacaacatg 1750

 actgactcct aacattgtgt ttcctgataa ccccttcaca ttggaagggt 1800

 caaataatcc ttctggaatc tttagccgct ctgcaccaaa atcacaattg 1850

 tagccattgg ggaattcata atgaacagtt ggcatctgtg cagccacttg 1900

 ttcatcataa gttgaatctg acacttgaag taccgaagct tgaaaatcct 1950

 ggataacaca attacacata taattgtgcc aagacctcgt aacctgaggc 2000

 aacttctctt ttcttttcca gtttgctgga gatccttcac gaacagcttc 2050

 ttttgatgca atcatatatg gaggaaccaa ttcaatattc atttcttgga 2100

 agagttctct gcactgcata gtaataaagt ctccagcaag aggggatttc 2150

 acaatgcctt gttgaaggac atagccatcg tggactggaa ttgcagtggt 2200

 atgagtggct ccactgtcca aaatcagccc agtagaacga ccattagcaa 2250

 atgctgtcaa aactgcagtt ttgcaaagga agaaggcagg gatgttgtag 2300

 tgttcaaaca ttaactctgt cagtttctct ctctttgctc tagtattcca 2350

 cggtgcctct gacatgagaa caggatggag actggcttct gatttgacat 2400

 gcattttgta ggtatgatcc aaaatagctt ggaaactatc ccagtcttca 2450

 accatcccat tttttagagg tgaaatggcc tccatattct ccctcggaac 2500

 acgcagagca ttagtatcta tgtagtaggt gggaccgcct tgtttgcctt 2550

 tatcgccatc tatttccatt aatgtgcttc cgtcatctct ttctaccacc 2600

 ataccaatag ctgtaggaaa atccaccttg gggcagtcct caccagcata 2650

 accagctctc acagtatagg atccaatgtc aaaaacaagg gctccaactt 2700

 catctccccc gtaccacgcc gccgctcatg gctgctgccg gcgcgactcc 2750

 taccctaagg gctaactggc gaagtgactg cagtggccgc gactgcgagt 2800

 ctcgaggagc gatagcccct gactccctta acttccaccg ccacccacct 2850

 caggcaacaa agcgg 2865

<210> 3928
<211> 886
<212> DNA
<213> Homo sapien

<400> 3928
 gtcggttccg ggcgttacca tcgtccgtgc gcaccgcccg gcgtccaggt 50

 gagtctccca tctgcagaga cgcggacgcg ccggcccgca gttggcctgc 100

 ggagcgcggt ggacggtttg gcgcccacca ggcgatcaat actttggatt 150

 tttaatttct agatttggca attcttcgct gaagtcatca tgagcttttt 200

 ccaactcctg atgaaaagga aggaactcat tcccttggtg gtgttcatga 250

 ctgtggcggc gggtggagcc tcatctttcg ctgtgtattc tctttggaaa 300

 accgatgtga tccttgatcg aaaaaaaaat ccagaacctt gggaaactgt 350

 ggaccctact gtacctcaaa agcttataac aatcaaccaa caatggaaac 400

 ccattgaaga gttgcaaaat gtccaaaggg tgaccaaatg acgagccctc 450

 gcctctttct tctgaagagt actctataaa tctagtggaa acatttctgc 500

 acaaactaga ttctggacac cagtgtgcgg aaatgcttct gctacatttt 550

 tagggtttgt ctacattttt tgggctctgg ataaggaatt aaaggagtgc 600

 agcaataact gcactgtcta aaagtttgtg cttattttct tgtaaatttg 650

 aatattgcat attgaaattt ttgtttatga tctatgaatg tttttcttaa 700

 aatttacaaa gctttgtaaa ttagattttc tttaataaaa tgccatttgt 750

 gcaagatttc tcaaagatta ggtatatatt taaatggaag agaaaatatt 800

 tttatgggag aaaaatacat ttgaaccatg aaatttcatc ttttaaataa 850

 catccagtac agatatctgt gtaaaaaaaa aaaaaa 886

<210> 3929
<211> 83
<212> PRT
<213> Homo sapien

<400> 3929
 Met Ser Phe Phe Gln Leu Leu Met Lys Arg Lys Glu Leu Ile Pro
   1               5                  10                  15

 Leu Val Val Phe Met Thr Val Ala Ala Gly Gly Ala Ser Ser Phe
                  20                  25                  30

 Ala Val Tyr Ser Leu Trp Lys Thr Asp Val Ile Leu Asp Arg Lys
                  35                  40                  45

 Lys Asn Pro Glu Pro Trp Glu Thr Val Asp Pro Thr Val Pro Gln
                  50                  55                  60

 Lys Leu Ile Thr Ile Asn Gln Gln Trp Lys Pro Ile Glu Glu Leu
                  65                  70                  75

 Gln Asn Val Gln Arg Val Thr Lys
                  80

<210> 3930
<211> 1027
<212> DNA
<213> Homo sapien

<400> 3930
 gaatctctcg cgggcagcag ggcgcgcgct gcacgcacag tactaggtca 50

 ggtggtgctc ccgggtgagg agctgctcct gccggaacag gaggacgcgg 100

 aaggccctgg gggtgcagtg gagcgaccgt tgagcctgaa tgctagagcg 150

 tgctcgcggg tgcgcgtttg tatgcggtcc gggccttcga cgctgtgggg 200

 accgcctgct ggtcaccaag tgcggccgcc tccgtcacaa ggagcccggc 250

 agtggaggcg gcggcggtgt ttactgggtg gactctcagc agaagcggta 300

 tgttccagta aaaggagacc atgtgattgg catagtgaca gctaaatctg 350

 gagatatatt caaagttgat gttggaggga gtgagccagc ttctttgtct 400

 tacttgtcat ttgaaggtgc aactaaaaga aacagaccaa atgtgcaggt 450

 tggagatctc atctatggcc agtttgtggt tgctaataaa gacatggaac 500

 cagagatggt ctgtattgac agctgtggac gagccaatgg aatgggtgtc 550

 attggacagg atggtctgct ttttaaagtg actctgggct taattagaaa 600

 gctattagct ccagattgtg aaatcataca ggaagtggga aaactctatc 650

 cactggagat agtatttgga atgaatggaa gaatatgggt taaggcaaaa 700

 accatccagc agactttaat tttggcaaac attttagaag cttgtgaaca 750

 catgacgtca gatcaaagaa aacagatctt ctccagattg gcagaaagtt 800

 gatataggtg gactttttta caggtcagtt gaggcaaaaa actatgggtt 850

 ttttcaggtg aacctccccc atttaaatac tcagaagata aggtgtgaat 900

 gtatgtatta ttagagtccg aaagtatttt tataagttac tggttttcac 950

 ccacgctttt gtgggagaga aaatcattgc aaaatcattt tttttgttcg 1000

 gtacaataaa gtttactaaa aaacaaa 1027

<210> 3931
<211> 220
<212> PRT
<213> Homo sapien

<400> 3931
 Met Leu Glu Arg Ala Arg Gly Cys Ala Phe Val Cys Gly Pro Gly
   1               5                  10                  15

 Leu Arg Arg Cys Gly Asp Arg Leu Leu Val Thr Lys Cys Gly Arg
                  20                  25                  30

 Leu Arg His Lys Glu Pro Gly Ser Gly Gly Gly Gly Gly Val Tyr
                  35                  40                  45

 Trp Val Asp Ser Gln Gln Lys Arg Tyr Val Pro Val Lys Gly Asp
                  50                  55                  60

 His Val Ile Gly Ile Val Thr Ala Lys Ser Gly Asp Ile Phe Lys
                  65                  70                  75

 Val Asp Val Gly Gly Ser Glu Pro Ala Ser Leu Ser Tyr Leu Ser
                  80                  85                  90

 Phe Glu Gly Ala Thr Lys Arg Asn Arg Pro Asn Val Gln Val Gly
                  95                 100                 105

 Asp Leu Ile Tyr Gly Gln Phe Val Val Ala Asn Lys Asp Met Glu
                 110                 115                 120

 Pro Glu Met Val Cys Ile Asp Ser Cys Gly Arg Ala Asn Gly Met
                 125                 130                 135

 Gly Val Ile Gly Gln Asp Gly Leu Leu Phe Lys Val Thr Leu Gly
                 140                 145                 150

 Leu Ile Arg Lys Leu Leu Ala Pro Asp Cys Glu Ile Ile Gln Glu
                 155                 160                 165

 Val Gly Lys Leu Tyr Pro Leu Glu Ile Val Phe Gly Met Asn Gly
                 170                 175                 180

 Arg Ile Trp Val Lys Ala Lys Thr Ile Gln Gln Thr Leu Ile Leu
                 185                 190                 195

 Ala Asn Ile Leu Glu Ala Cys Glu His Met Thr Ser Asp Gln Arg
                 200                 205                 210

 Lys Gln Ile Phe Ser Arg Leu Ala Glu Ser
                 215                 220

<210> 3932
<211> 1204
<212> DNA
<213> Homo sapien

<400> 3932
 gaaattctta caaaaactga aagtgaaatg aggaagacag attgagcaat 50

 ccaatcggag ggtaaatgcc agcaaaccta ctgtacagta ggggtagaga 100

 tgcagaaagg cagaaaggag aaaattcagg ataactctcc tgaggggtga 150

 gccaagccct gccatgtagt gcacgcagga catcaacaaa cacagataac 200

 aggaaatgat ccattccctg tggtcactta ttctaaaggc cccaaccttc 250

 aaagttcaag tagtgatatg gatgactcca cagaaaggga gcagtcacgc 300

 cttacttctt gccttaagaa aagagaagaa atgaaactga aggagtgtgt 350

 ttccatcctc ccacggaagg aaagcccctc tgtccgatcc tccaaagacg 400

 gaaagctgct ggctgcaacc ttgctgctgg cactgctgtc ttgctgcctc 450

 acggtggtgt ctttctacca ggtggccgcc ctgcaagggg acctggccag 500

 cctccgggca gagctgcagg gccaccacgc ggagaagctg ccagcaggag 550

 caggagcccc caaggccggc ctggaggaag ctccagctgt caccgcggga 600

 ctgaaaatct ttgaaccacc agctccagga gaaggcaact ccagtcagaa 650

 cagcagaaat aagcgtgccg ttcagggtcc agaagaaaca gtcactcaag 700

 actgcttgca actgattgca gacagtgaaa caccaactat acaaaaagga 750

 tcttacacat ttgttccatg gcttctcagc tttaaaaggg gaagtgccct 800

 agaagaaaaa gagaataaaa tattggtcaa agaaactggt tactttttta 850

 tatatggtca ggttttatat actgataaga cctacgccat gggacatcta 900

 attcagagga agaaggtcca tgtctttggg gatgaattga gtctggtgac 950

 tttgtttcga tgtattcaaa atatgcctga aacactaccc aataattcct 1000

 gctattcagc tggcattgca aaactggaag aaggagatga actccaactt 1050

 gcaataccaa gagaaaatgc acaaatatca ctggatggag atgtcacatt 1100

 ttttggtgca ttgaaactgc tgtgacctac ttacaccatg tctgtagcta 1150

 ttttcctccc tttctctgta cctctaagaa gaaagaatct aactgaaaat 1200

 acca 1204

<210> 3933
<211> 285
<212> PRT
<213> Homo sapien

<400> 3933
 Met Asp Asp Ser Thr Glu Arg Glu Gln Ser Arg Leu Thr Ser Cys
   1               5                  10                  15

 Leu Lys Lys Arg Glu Glu Met Lys Leu Lys Glu Cys Val Ser Ile
                  20                  25                  30

 Leu Pro Arg Lys Glu Ser Pro Ser Val Arg Ser Ser Lys Asp Gly
                  35                  40                  45

 Lys Leu Leu Ala Ala Thr Leu Leu Leu Ala Leu Leu Ser Cys Cys
                  50                  55                  60

 Leu Thr Val Val Ser Phe Tyr Gln Val Ala Ala Leu Gln Gly Asp
                  65                  70                  75

 Leu Ala Ser Leu Arg Ala Glu Leu Gln Gly His His Ala Glu Lys
                  80                  85                  90

 Leu Pro Ala Gly Ala Gly Ala Pro Lys Ala Gly Leu Glu Glu Ala
                  95                 100                 105

 Pro Ala Val Thr Ala Gly Leu Lys Ile Phe Glu Pro Pro Ala Pro
                 110                 115                 120

 Gly Glu Gly Asn Ser Ser Gln Asn Ser Arg Asn Lys Arg Ala Val
                 125                 130                 135

 Gln Gly Pro Glu Glu Thr Val Thr Gln Asp Cys Leu Gln Leu Ile
                 140                 145                 150

 Ala Asp Ser Glu Thr Pro Thr Ile Gln Lys Gly Ser Tyr Thr Phe
                 155                 160                 165

 Val Pro Trp Leu Leu Ser Phe Lys Arg Gly Ser Ala Leu Glu Glu
                 170                 175                 180

 Lys Glu Asn Lys Ile Leu Val Lys Glu Thr Gly Tyr Phe Phe Ile
                 185                 190                 195

 Tyr Gly Gln Val Leu Tyr Thr Asp Lys Thr Tyr Ala Met Gly His
                 200                 205                 210

 Leu Ile Gln Arg Lys Lys Val His Val Phe Gly Asp Glu Leu Ser
                 215                 220                 225

 Leu Val Thr Leu Phe Arg Cys Ile Gln Asn Met Pro Glu Thr Leu
                 230                 235                 240

 Pro Asn Asn Ser Cys Tyr Ser Ala Gly Ile Ala Lys Leu Glu Glu
                 245                 250                 255

 Gly Asp Glu Leu Gln Leu Ala Ile Pro Arg Glu Asn Ala Gln Ile
                 260                 265                 270

 Ser Leu Asp Gly Asp Val Thr Phe Phe Gly Ala Leu Lys Leu Leu
                 275                 280                 285

<210> 3934
<211> 924
<212> DNA
<213> Homo sapien

<400> 3934
 tgaggagttt ccacataggc aaagggtgcc aatatttaac tgacatctgg 50

 tttctttttg gaagttttct ttcacatggt ttgtcattac aagacaaggt 100

 ctgcccagcc aggtggatct accttgcccc catcacctgc cgcccccatc 150

 aaacatgttg ggacaatgcc cataggaatg gacctccttc cccgtctcca 200

 gctgggactg gcgtttttta gtctctggag tatgatggtt ctcatgggta 250

 ggatgagatc tttcggcaga aaggtcttcg gtggtgctct gagcctgcgc 300

 tgcataggac tgagcagacc cacctcctcc agcttgggtg gccctgccac 350

 tcctggttcc aagtctctcc tttcctggca ggtcttaagg gaagattgta 400

 ccccctcacc ctttacatac ccagaatcat cagtatgtca cttcctaatt 450

 tctatcagtg tatctcatta tttcatactg ttttactaat cctaagtcta 500

 aacagatttg ctcaaaagga gaccattcta ttttttaaag tacttagtga 550

 tacacgtata agctttgcat ggacgaatta aataagcaca ttgacctttt 600

 cttgtacatt cagaacctga acatccatgt gaaaactggg tccatttttg 650

 agagatgtga aactacagtt tatttgtaat aaataaatat aatctatccg 700

 gtatatgcat atatctatat gctgtgttaa gtggtaatgg gtacattaca 750

 gtctgtgaga gatggatcgc tccctctgta aggaacaaga cgttctcagc 800

 tgatgtcacg gtaggtttag attctgtaga gtgttcccca acccgcaccg 850

 ttctgtacct ctcacaccac tgcttgcccg ggcagtagtg gctgaccaat 900

 aaagaccttt acctgttttg tatg 924

<210> 3935
<211> 137
<212> PRT
<213> Homo sapien

<400> 3935
 Met Val Cys His Tyr Lys Thr Arg Ser Ala Gln Pro Gly Gly Ser
   1               5                  10                  15

 Thr Leu Pro Pro Ser Pro Ala Ala Pro Ile Lys His Val Gly Thr
                  20                  25                  30

 Met Pro Ile Gly Met Asp Leu Leu Pro Arg Leu Gln Leu Gly Leu
                  35                  40                  45

 Ala Phe Phe Ser Leu Trp Ser Met Met Val Leu Met Gly Arg Met
                  50                  55                  60

 Arg Ser Phe Gly Arg Lys Val Phe Gly Gly Ala Leu Ser Leu Arg
                  65                  70                  75

 Cys Ile Gly Leu Ser Arg Pro Thr Ser Ser Ser Leu Gly Gly Pro
                  80                  85                  90

 Ala Thr Pro Gly Ser Lys Ser Leu Leu Ser Trp Gln Val Leu Arg
                  95                 100                 105

 Glu Asp Cys Thr Pro Ser Pro Phe Thr Tyr Pro Glu Ser Ser Val
                 110                 115                 120

 Cys His Phe Leu Ile Ser Ile Ser Val Ser His Tyr Phe Ile Leu
                 125                 130                 135

 Phe Tyr


<210> 3936
<211> 2575
<212> DNA
<213> Homo sapien

<400> 3936
 acaagccatg agcagcgacc cgcgggcgac gcgctgtccc tggcagccgc 50

 tgagcccgac cccgcaggca gctcgccgct ccctagcacc ttctccagtc 100

 gacactctcg cgcccggaga aacatgattc ccgtgacaga attccggcag 150

 ttctctgagc agcagcctgc cttccgagtg ctgaagccat ggtgggatgt 200

 gtttaccgat tacctctcag tagccatgct catgattggc gtgtttggat 250

 gtactttaca ggtcatgcaa gacaagataa tctgccttcc gaaaagagtg 300

 cagcctgctc agaaccactc ttccctttcg aatgtctctc aagcagttgc 350

 cagtaccact ccactgcctc cacctaaacc atctcctgct aaccccatca 400

 ctgtggaaat gaaaggcctg aagacagatt tggaccttca gcagtacagc 450

 tttataaatc agatgtgtta tgagcgagcc ctccactggt atgccaagta 500

 tttcccttac cttgtcctca tccataccct ggtctttatg ctctgcagta 550

 acttttggtt caaattccct ggttccagct ccaaaataga acatttcatc 600

 tccattctgg ggaagtgttt tgactctcct tggaccacac gggctttatc 650

 tgaagtgtct ggggaggact cagaagaaaa ggacaacagg aagaacaaca 700

 tgaacaggtc caacaccatc caatctggtc cagaaggcag cctggtcaac 750

 tctcagtctt taaagtccat tcctgagaag tttgtagttg ataaatccac 800

 tgcaggggct ctggataaaa aggaaggtga gcaggctaag gccttatttg 850

 agaaggtgaa gaagttcagg ctgcatgtgg aagaaggtga tattctatat 900

 gccatgtatg ttcgccagac tgtacttaaa gttatcaaat tcctaatcat 950

 cattgcatat aatagtgctc tggtttccaa ggtccagttt acagtggact 1000

 gtaatgtgga cattcaggac atgactggat ataaaaactt ttcttgcaat 1050

 cataccatgg cacacttgtt ctcaaaactg tccttttgct atctgtgctt 1100

 tgttagtatc tatggattga cgtgccttta taccttatac tggctgttct 1150

 accgttctct acgggaatat tcctttgagt atgtccgtca ggagactgga 1200

 attgatgata ttccagatgt gaaaaatgac tttgctttta tgcttcatat 1250

 gatagatcag tatgaccctc tctattccaa gagatttgca gtgttcctgt 1300

 ctgaagtcag tgaaaacaaa ttaaagcagc tgaacttaaa taacgaatgg 1350

 actcctgata aactgaggca gaagctacag acaaatgccc ataatcgact 1400

 ggaattgcct cttatcatgc tctctggcct tccagacact gtttttgaaa 1450

 tcacagagtt gcaatctcta aaacttgaaa tcattaagaa cgtaatgata 1500

 ccagccacca ttgcacagct agacaatctt caagagctct ctctgcacca 1550

 gtgttctgtc aaaatccaca gtgcggcgct ctctttcctg aaggaaaacc 1600

 tcaaggtctt gagcgtcaag tttgatgaca tgagggaact ccccccctgg 1650

 atgtatgggc tccgaaatct ggaagagctg tacctagttg gctctctaag 1700

 tcatgatatt tccagaaatg tcacccttga gtctctgcgg gatctcaaaa 1750

 gccttaaaat tctctctatc aaaagcaacg tttccaaaat ccctcaggca 1800

 gtggttgatg tttccagcca tctccagaag atgtgcatac ataatgatgg 1850

 caccaagctg gtgatgctca acaacttaaa gaagatgacc aatctgacag 1900

 agctggagct ggtccactgt gacctggagc gtattcctca tgctgtgttc 1950

 agcctactca gcctccagga attggacctg aaggaaaaca atctgaaatc 2000

 tatagaagaa atcgttagct ttcagcactt aagaaagttg acagtgctaa 2050

 aactgtggca taacagcatc acctacatcc cagagcatat aaagaaactc 2100

 accagcctgg aacgcctgtc ctttagtcac aataaaatag aggtgctgcc 2150

 ttcccacctc ttcctatgca acaagatccg atacttggac ttatcgtaca 2200

 atgacattcg atttatcccc cctgaaattg gagttctaca aagtttacag 2250

 tatttttcca tcacatgtaa caaagtggaa agccttccag atgaactcta 2300

 cttctgcaag aaacttaaaa ctctgaagat tggaaaaaac agcctatctg 2350

 tactttcacc gaaaattgga aatttgctat ttctttccta cttagatgta 2400

 aaaggtaatc actttgaaat cctccctcct gaactgggtg actgtcgggc 2450

 tctgaagcga gctggtttag ttgtagaaga tgctctgttt gaaactctgc 2500

 cttctgacgt ccgggagcaa atgaaaacag aataacttat ttttcgttaa 2550

 agtttgactg aaacacgctt ctacc 2575

<210> 3937
<211> 803
<212> PRT
<213> Homo sapien

<400> 3937
 Met Ile Pro Val Thr Glu Phe Arg Gln Phe Ser Glu Gln Gln Pro
   1               5                  10                  15

 Ala Phe Arg Val Leu Lys Pro Trp Trp Asp Val Phe Thr Asp Tyr
                  20                  25                  30

 Leu Ser Val Ala Met Leu Met Ile Gly Val Phe Gly Cys Thr Leu
                  35                  40                  45

 Gln Val Met Gln Asp Lys Ile Ile Cys Leu Pro Lys Arg Val Gln
                  50                  55                  60

 Pro Ala Gln Asn His Ser Ser Leu Ser Asn Val Ser Gln Ala Val
                  65                  70                  75

 Ala Ser Thr Thr Pro Leu Pro Pro Pro Lys Pro Ser Pro Ala Asn
                  80                  85                  90

 Pro Ile Thr Val Glu Met Lys Gly Leu Lys Thr Asp Leu Asp Leu
                  95                 100                 105

 Gln Gln Tyr Ser Phe Ile Asn Gln Met Cys Tyr Glu Arg Ala Leu
                 110                 115                 120

 His Trp Tyr Ala Lys Tyr Phe Pro Tyr Leu Val Leu Ile His Thr
                 125                 130                 135

 Leu Val Phe Met Leu Cys Ser Asn Phe Trp Phe Lys Phe Pro Gly
                 140                 145                 150

 Ser Ser Ser Lys Ile Glu His Phe Ile Ser Ile Leu Gly Lys Cys
                 155                 160                 165

 Phe Asp Ser Pro Trp Thr Thr Arg Ala Leu Ser Glu Val Ser Gly
                 170                 175                 180

 Glu Asp Ser Glu Glu Lys Asp Asn Arg Lys Asn Asn Met Asn Arg
                 185                 190                 195

 Ser Asn Thr Ile Gln Ser Gly Pro Glu Gly Ser Leu Val Asn Ser
                 200                 205                 210

 Gln Ser Leu Lys Ser Ile Pro Glu Lys Phe Val Val Asp Lys Ser
                 215                 220                 225

 Thr Ala Gly Ala Leu Asp Lys Lys Glu Gly Glu Gln Ala Lys Ala
                 230                 235                 240

 Leu Phe Glu Lys Val Lys Lys Phe Arg Leu His Val Glu Glu Gly
                 245                 250                 255

 Asp Ile Leu Tyr Ala Met Tyr Val Arg Gln Thr Val Leu Lys Val
                 260                 265                 270

 Ile Lys Phe Leu Ile Ile Ile Ala Tyr Asn Ser Ala Leu Val Ser
                 275                 280                 285

 Lys Val Gln Phe Thr Val Asp Cys Asn Val Asp Ile Gln Asp Met
                 290                 295                 300

 Thr Gly Tyr Lys Asn Phe Ser Cys Asn His Thr Met Ala His Leu
                 305                 310                 315

 Phe Ser Lys Leu Ser Phe Cys Tyr Leu Cys Phe Val Ser Ile Tyr
                 320                 325                 330

 Gly Leu Thr Cys Leu Tyr Thr Leu Tyr Trp Leu Phe Tyr Arg Ser
                 335                 340                 345

 Leu Arg Glu Tyr Ser Phe Glu Tyr Val Arg Gln Glu Thr Gly Ile
                 350                 355                 360

 Asp Asp Ile Pro Asp Val Lys Asn Asp Phe Ala Phe Met Leu His
                 365                 370                 375

 Met Ile Asp Gln Tyr Asp Pro Leu Tyr Ser Lys Arg Phe Ala Val
                 380                 385                 390

 Phe Leu Ser Glu Val Ser Glu Asn Lys Leu Lys Gln Leu Asn Leu
                 395                 400                 405

 Asn Asn Glu Trp Thr Pro Asp Lys Leu Arg Gln Lys Leu Gln Thr
                 410                 415                 420

 Asn Ala His Asn Arg Leu Glu Leu Pro Leu Ile Met Leu Ser Gly
                 425                 430                 435

 Leu Pro Asp Thr Val Phe Glu Ile Thr Glu Leu Gln Ser Leu Lys
                 440                 445                 450

 Leu Glu Ile Ile Lys Asn Val Met Ile Pro Ala Thr Ile Ala Gln
                 455                 460                 465

 Leu Asp Asn Leu Gln Glu Leu Ser Leu His Gln Cys Ser Val Lys
                 470                 475                 480

 Ile His Ser Ala Ala Leu Ser Phe Leu Lys Glu Asn Leu Lys Val
                 485                 490                 495

 Leu Ser Val Lys Phe Asp Asp Met Arg Glu Leu Pro Pro Trp Met
                 500                 505                 510

 Tyr Gly Leu Arg Asn Leu Glu Glu Leu Tyr Leu Val Gly Ser Leu
                 515                 520                 525

 Ser His Asp Ile Ser Arg Asn Val Thr Leu Glu Ser Leu Arg Asp
                 530                 535                 540

 Leu Lys Ser Leu Lys Ile Leu Ser Ile Lys Ser Asn Val Ser Lys
                 545                 550                 555

 Ile Pro Gln Ala Val Val Asp Val Ser Ser His Leu Gln Lys Met
                 560                 565                 570

 Cys Ile His Asn Asp Gly Thr Lys Leu Val Met Leu Asn Asn Leu
                 575                 580                 585

 Lys Lys Met Thr Asn Leu Thr Glu Leu Glu Leu Val His Cys Asp
                 590                 595                 600

 Leu Glu Arg Ile Pro His Ala Val Phe Ser Leu Leu Ser Leu Gln
                 605                 610                 615

 Glu Leu Asp Leu Lys Glu Asn Asn Leu Lys Ser Ile Glu Glu Ile
                 620                 625                 630

 Val Ser Phe Gln His Leu Arg Lys Leu Thr Val Leu Lys Leu Trp
                 635                 640                 645

 His Asn Ser Ile Thr Tyr Ile Pro Glu His Ile Lys Lys Leu Thr
                 650                 655                 660

 Ser Leu Glu Arg Leu Ser Phe Ser His Asn Lys Ile Glu Val Leu
                 665                 670                 675

 Pro Ser His Leu Phe Leu Cys Asn Lys Ile Arg Tyr Leu Asp Leu
                 680                 685                 690

 Ser Tyr Asn Asp Ile Arg Phe Ile Pro Pro Glu Ile Gly Val Leu
                 695                 700                 705

 Gln Ser Leu Gln Tyr Phe Ser Ile Thr Cys Asn Lys Val Glu Ser
                 710                 715                 720

 Leu Pro Asp Glu Leu Tyr Phe Cys Lys Lys Leu Lys Thr Leu Lys
                 725                 730                 735

 Ile Gly Lys Asn Ser Leu Ser Val Leu Ser Pro Lys Ile Gly Asn
                 740                 745                 750

 Leu Leu Phe Leu Ser Tyr Leu Asp Val Lys Gly Asn His Phe Glu
                 755                 760                 765

 Ile Leu Pro Pro Glu Leu Gly Asp Cys Arg Ala Leu Lys Arg Ala
                 770                 775                 780

 Gly Leu Val Val Glu Asp Ala Leu Phe Glu Thr Leu Pro Ser Asp
                 785                 790                 795

 Val Arg Glu Gln Met Lys Thr Glu
                 800

<210> 3938
<211> 1645
<212> DNA
<213> Homo sapien

<400> 3938
 ggattttcct tggtcttaag atgggtagaa atgtgatgcg acacatgtct 50

 gatgacttag gaagttatgt ttctctttcg tgtgatgact tttcttcaca 100

 ggaattagag attttcattt gctccttttc ctcctcctgg cttcaaatgt 150

 ttgttgcaga ggcagtcttt aaaaagttgt gtctacagag ctctggcagt 200

 gtttcttctg agccactctc tcttcagaaa atggtatatt cctatttacc 250

 agccttgggg aaaactggtg tgcttgggtc tggaaagatt caggtgtcaa 300

 agaaaatagg acagcggcct tgttttgact ctcagagaac cttactaatg 350

 ctgaatggta ctaaacaaaa acaagtcgaa gggctgccag agttactaga 400

 cctgaacctt gctaaatgtt cctcatcatt aaaaaaattg aaaaagaagt 450

 cagaaggaga attgtcatgt tccaaggaga attgcccctc tgtagttaaa 500

 aagatgaatt ttcacaagac taatctaaaa ggagaaacag ccctgcatag 550

 agcttgcata aataaccaag tggagaaatt gattcttctt ctctctttgc 600

 caggaataga catcaatgtt aaagacaatg ctggctggac gcctttgcat 650

 gaagcctgta actatggcaa cacagtgtgt gtccaggaaa ttttgcaacg 700

 ttgtccagag gtagatctgc tcactcaagt ggacggggtg actcctttgc 750

 atgatgcact gtcaaacgga catgtagaaa ttggcaagct gctactacag 800

 catgggggcc cagtgctttt acaacagagg aatgctaagg gagaattgcc 850

 cttggattat gtggtttcac ctcaaatcaa agaagaactg tttgctatta 900

 caaaaataga agatacagtg gagaactttc atgcacaagc agagaaacat 950

 tttcattacc agcaacttga atttggctcc tttttactta gtaggatgtt 1000

 gctaaatttt tgttcaattt ttgatttatc ttcagagttc attttagctt 1050

 ccaaagggtt aactcatcta aatgaactgc ttatggcttg taaaagtcat 1100

 aaagaaacca ccagtgttca tactgactgg ttactggatc tttatgctgg 1150

 aaatataaag acattgcaga aactcccaca cattcttaag gaactgcctg 1200

 agaatttgaa agtgtgtcct ggggtacaca ctgaggcctt gatgataaca 1250

 ttggaaatga tgtgtcggtc agtcatggag ttttcatgat gatgctagaa 1300

 agtatggatt gactttctaa atctgttcag tttgcattgg tacttactgt 1350

 ggacttcata gcttactgac agatagtaat ttgatttatt tattgacaga 1400

 ctttgcagcc ttgctaaatt ttaaaagcat ttttaaaaaa acttctacaa 1450

 aactctagta tgggcttctg actttttcca gggtgtagaa tttgactcaa 1500

 aagtaaaaat aattttgttt tagtatattc tactttcatt aatgtttttt 1550

 tgttctgaaa gtgatattat attgtacatg taaaattaat ttaaatattt 1600

 tttcaaataa aaatgtaatg tcctgtaaaa aaaaaaaaaa aaaaa 1645

<210> 3939
<211> 422
<212> PRT
<213> Homo sapien

<400> 3939
 Met Gly Arg Asn Val Met Arg His Met Ser Asp Asp Leu Gly Ser
   1               5                  10                  15

 Tyr Val Ser Leu Ser Cys Asp Asp Phe Ser Ser Gln Glu Leu Glu
                  20                  25                  30

 Ile Phe Ile Cys Ser Phe Ser Ser Ser Trp Leu Gln Met Phe Val
                  35                  40                  45

 Ala Glu Ala Val Phe Lys Lys Leu Cys Leu Gln Ser Ser Gly Ser
                  50                  55                  60

 Val Ser Ser Glu Pro Leu Ser Leu Gln Lys Met Val Tyr Ser Tyr
                  65                  70                  75

 Leu Pro Ala Leu Gly Lys Thr Gly Val Leu Gly Ser Gly Lys Ile
                  80                  85                  90

 Gln Val Ser Lys Lys Ile Gly Gln Arg Pro Cys Phe Asp Ser Gln
                  95                 100                 105

 Arg Thr Leu Leu Met Leu Asn Gly Thr Lys Gln Lys Gln Val Glu
                 110                 115                 120

 Gly Leu Pro Glu Leu Leu Asp Leu Asn Leu Ala Lys Cys Ser Ser
                 125                 130                 135

 Ser Leu Lys Lys Leu Lys Lys Lys Ser Glu Gly Glu Leu Ser Cys
                 140                 145                 150

 Ser Lys Glu Asn Cys Pro Ser Val Val Lys Lys Met Asn Phe His
                 155                 160                 165

 Lys Thr Asn Leu Lys Gly Glu Thr Ala Leu His Arg Ala Cys Ile
                 170                 175                 180

 Asn Asn Gln Val Glu Lys Leu Ile Leu Leu Leu Ser Leu Pro Gly
                 185                 190                 195

 Ile Asp Ile Asn Val Lys Asp Asn Ala Gly Trp Thr Pro Leu His
                 200                 205                 210

 Glu Ala Cys Asn Tyr Gly Asn Thr Val Cys Val Gln Glu Ile Leu
                 215                 220                 225

 Gln Arg Cys Pro Glu Val Asp Leu Leu Thr Gln Val Asp Gly Val
                 230                 235                 240

 Thr Pro Leu His Asp Ala Leu Ser Asn Gly His Val Glu Ile Gly
                 245                 250                 255

 Lys Leu Leu Leu Gln His Gly Gly Pro Val Leu Leu Gln Gln Arg
                 260                 265                 270

 Asn Ala Lys Gly Glu Leu Pro Leu Asp Tyr Val Val Ser Pro Gln
                 275                 280                 285

 Ile Lys Glu Glu Leu Phe Ala Ile Thr Lys Ile Glu Asp Thr Val
                 290                 295                 300

 Glu Asn Phe His Ala Gln Ala Glu Lys His Phe His Tyr Gln Gln
                 305                 310                 315

 Leu Glu Phe Gly Ser Phe Leu Leu Ser Arg Met Leu Leu Asn Phe
                 320                 325                 330

 Cys Ser Ile Phe Asp Leu Ser Ser Glu Phe Ile Leu Ala Ser Lys
                 335                 340                 345

 Gly Leu Thr His Leu Asn Glu Leu Leu Met Ala Cys Lys Ser His
                 350                 355                 360

 Lys Glu Thr Thr Ser Val His Thr Asp Trp Leu Leu Asp Leu Tyr
                 365                 370                 375

 Ala Gly Asn Ile Lys Thr Leu Gln Lys Leu Pro His Ile Leu Lys
                 380                 385                 390

 Glu Leu Pro Glu Asn Leu Lys Val Cys Pro Gly Val His Thr Glu
                 395                 400                 405

 Ala Leu Met Ile Thr Leu Glu Met Met Cys Arg Ser Val Met Glu
                 410                 415                 420

 Phe Ser


<210> 3940
<211> 4334
<212> DNA
<213> Homo sapien

<400> 3940
 gagtgtcact ctgtccccca gtctggcgtg caatggtttg atctcggctc 50

 actgcaacct ccacctcccg ggttcaacct cctgcctcag ccttccgagc 100

 agctgggact acaggagcct gccaccacat ctggcgaatt tttgtatttt 150

 tagtagagaa gggggttcag catgttgtcc aggttggtct tgaactcctg 200

 acctcaggtg atccagccac tttggcctca caaagtgctg ggattatagg 250

 caagagcgat ggcgcccggc ccactcagca ggattcctag aatgggcacg 300

 agctctgccc tcatcacagt ccaaaagtga gcacctgcct ggagctgccc 350

 agaaacagcc ttgtggggtg gggttggtgt ctgacctccc tccccggggg 400

 ccttcgcagg cttctctgct ggtgcttctg tgcctgtggg tctggattcc 450

 tccagggcct gatcctgggt gcagatgcag ctggaagccc tgaacctgct 500

 gcacacacta gtctgggcac ggagtctctg ccgtgccgga gctgtgcaga 550

 cacaggagcg gctgtcaggc agtgccagcc ctgagcaagt gccagctggt 600

 gagtgctgtg ctctgcagga gtatgaggcc gccgtggagc agctcaagag 650

 cgagcagatc cgggcgcagg ctgaggagag gaggaagacc ctgagcgagg 700

 agacccggca gcaccaggcc agggcccagt atcaagacaa gctggcccgg 750

 cagcgctacg aggaccaact gaagcagcag caacttctca atgaggagaa 800

 tttacggaag caggaggagt ccgtgcagaa gcaggaagcc atgcggcgag 850

 ccaccgtgga gcgggagatg gagctgcggc acaagaatga gatgctgcga 900

 gtggagaccg aggcccgggc gcgcgccaag gccgagcggg agaatgcaga 950

 catcatccgc gagcagatcc gcctgaaggc gtccgagcac cgtcagaccg 1000

 tcttggagtc catcaggacg gctggcacct tgtttgggga aggattccgt 1050

 gcctttgtga cagaccggga caaagtgaca gccacggtgg ctgggctgac 1100

 gctgctggct gtcggggtct actcagccaa gaatgcgaca gccgtcactg 1150

 gccgcttcat cgaggctcgg ctggggaagc cgtccctagt gagggagacg 1200

 tcccgcatca cggtgctgga ggcgctgcgg caccccatcc aggtcagccg 1250

 gcggctcctc agtcgacccc aggacgtgct ggagggtgtt gtgcttagtc 1300

 ccagcctgga agcacgggtg cgcgacatcg ccatagcaac caggaacacc 1350

 aagaagaacc ggggcctgta caggcacatc ctgctgtatg ggccaccagg 1400

 caccgggaag acgctgtttg ccaagaaact cgccctgcac tcaggcatgg 1450

 actacgccat catgacaggc ggggacgtgg cccccatggg gcgggaaggc 1500

 gtgaccgcca tgcacaagct ctttgactgg gccaatacca gccggcgcgg 1550

 cctcctgctc ttcatggatg aagcagacgc cttccttcgg aagcgagcca 1600

 ctgaggagat aagcaaggac ctcagagcca cactgaacgc cttcctgtac 1650

 cacatgggcc aacacagcaa caaattcatg ctggtcctgg ccagcaatct 1700

 gcctgagcag ttcgactgtg ccatcaacag ccgcattgac gtgatggtcc 1750

 acttcgacct gccgcagcag gaggagcggg agcgcctggt gagactgcat 1800

 tttgacaact gtgttcttaa gccggccaca gaaggaaaac ggcgcctgaa 1850

 gctggcccag tttgactacg ggaggaagtg ctcggaggtc gctcggctga 1900

 cggagggcat gtcgggccgg gagatcgctc agctggccgt gtcctggcag 1950

 gccacggcat atgcctccaa ggacggggtc ctcactgagg ccatgatgga 2000

 cgcctgtgtg caagatgctg tccagcagta ccgacagaag atgcgctggc 2050

 tgaaggcgga ggggcctggg cgcggggtcg agcaccccct atccggagtc 2100

 caaggcgaga ccctcacctc atggagcctg gccacggacc cctcctaccc 2150

 ctgccttgcc ggcccctgca catttaggat atgctcctgg atggggactg 2200

 ggctgtgccc agggcctctg tcccccagga tgtcttgtgg tggcggtcgg 2250

 ccgttctgcc ccccagggca ccccctgttg taggcactgg ctagggaggg 2300

 gcaggcctcc ttcctgcccc tcgagacact cttgggagat gcattttccg 2350

 tctggctcac agggggaggg tgaggctttg taccccagcc cctgcccagg 2400

 ccactgtgag ggtgggtgct ggctgagccc ctggggcaga aggagtgggg 2450

 caggcggggt ctttgttctc ggctcccaca gcagagccag gtgagggggg 2500

 gcctgccagg actagacaga agtggggcgg cctgaaccct gcttccagcc 2550

 atggccaggg gccacggaac ccggcagggg tgtctgaggc cgccctgtca 2600

 gctggccggt ccaagcctgt ggctggagct ggtgtgtgtt tatctaataa 2650

 agtcccacag gtgcctcacc gccgtgtctc tctattgact gacactgctc 2700

 ggggtttcag gggcgcccta gcgtcctcct ggggtcaaag gtgacataag 2750

 aggcagaggc tggagctttc tagaatttac tgatcacaga gcggtgtgct 2800

 tcacatcagc ctcgcgccac atccgagttg gggtctgaat gctgcccggg 2850

 actgccgcct gcgccccacc agcccctccc tcctgaagga ggggcacccc 2900

 gagaagaatg aggctgcaga gtgatgtggg ggccagcggt gacttcatga 2950

 ccacactgcg cccaggtgta agagggcacg cttctgccca ggcatcgtcc 3000

 atggaagaca cgcagtcggc cactgcagcc tcggtcctgg gtgccctggg 3050

 gctgggtcac tgggggccac aggccacact gggagaccac agtcctggca 3100

 tgccatgcag ctccctgtcc ccagaggtct gctcagatgc agagagctca 3150

 ggaaccacac tcgctgcctg aattctggga gcagagcgtg gtacccactg 3200

 cctggctggg gcctactctg ggactgcagc ccctgtcccc gctggcccag 3250

 gcttccggag gcagctgcgt ccctgtcttg gctcaaggtc aggccggagg 3300

 ccaggctgtc cacctgcatc tggaacctgc acagtcactc ctccaggtcc 3350

 tcgctgctgg aggactctca gacaggaaac ctttgctttg ggggcagggt 3400

 ggggtgcagg ggtggttggg ggaatcacag caacgagaca gcacagtgcc 3450

 atggcgcaga gcctcatatt ggtcgatgaa acaatgcttt ctgaactttg 3500

 tgtccttagg aagggtgtag gctgttggtt gaagtaggaa acagaagagg 3550

 agcctgggca cgcaacggtc ccatcggaga gcagacccct cggagctgca 3600

 gtgcttggag gggggcggtc tacctctgct cgctctctcc atttctctct 3650

 ctacctctgc tcgctctctc catttctctc tttttccttt tagagatggg 3700

 ttcttactct gagcccaggc tggagtgcag tggtgtgatt atagctcact 3750

 gcagcctcga cctcccaggc tcaagtgatc ctcctgcctc agcctgtcca 3800

 gtagccatac cctactaggc cctaattagc cccagaggcg tgcaccacca 3850

 cgcccgctaa tgctaaaaat ttgttgtaga gaccgagtct tgctataatg 3900

 cccaggctgg tctccaactc ttggcctcag gagatcctcc cgcctctaca 3950

 ggatgagcca ccaagcctgg cctcaattcc tctttaaagg aattgcctaa 4000

 atcttaaacc agcaatcaat actttgtatt taaaattaag ccaggttaga 4050

 ctgggctagg tggctcacgc ctgtaatccc agcactttgg gaggccaagg 4100

 cgggtgaatc atgaggtcag gagtttgaga ccatcctggc taacgtggca 4150

 aaaccccgtc tctactaaaa atacaaaaaa attagccggc atggtggtag 4200

 gtgactgtaa tcccagctac tcgggaggct gaggcaggag actcgcttgg 4250

 acctgggagg gggaggttgc agtgagccga gatcacgcca ctgcactcca 4300

 gcctgggcag catggcaaga acctgtcgct cttt 4334

<210> 3941
<211> 606
<212> PRT
<213> Homo sapien

<400> 3941
 Ser Trp Val Gln Met Gln Leu Glu Ala Leu Asn Leu Leu His Thr
   1               5                  10                  15

 Leu Val Trp Ala Arg Ser Leu Cys Arg Ala Gly Ala Val Gln Thr
                  20                  25                  30

 Gln Glu Arg Leu Ser Gly Ser Ala Ser Pro Glu Gln Val Pro Ala
                  35                  40                  45

 Gly Glu Cys Cys Ala Leu Gln Glu Tyr Glu Ala Ala Val Glu Gln
                  50                  55                  60

 Leu Lys Ser Glu Gln Ile Arg Ala Gln Ala Glu Glu Arg Arg Lys
                  65                  70                  75

 Thr Leu Ser Glu Glu Thr Arg Gln His Gln Ala Arg Ala Gln Tyr
                  80                  85                  90

 Gln Asp Lys Leu Ala Arg Gln Arg Tyr Glu Asp Gln Leu Lys Gln
                  95                 100                 105

 Gln Gln Leu Leu Asn Glu Glu Asn Leu Arg Lys Gln Glu Glu Ser
                 110                 115                 120

 Val Gln Lys Gln Glu Ala Met Arg Arg Ala Thr Val Glu Arg Glu
                 125                 130                 135

 Met Glu Leu Arg His Lys Asn Glu Met Leu Arg Val Glu Thr Glu
                 140                 145                 150

 Ala Arg Ala Arg Ala Lys Ala Glu Arg Glu Asn Ala Asp Ile Ile
                 155                 160                 165

 Arg Glu Gln Ile Arg Leu Lys Ala Ser Glu His Arg Gln Thr Val
                 170                 175                 180

 Leu Glu Ser Ile Arg Thr Ala Gly Thr Leu Phe Gly Glu Gly Phe
                 185                 190                 195

 Arg Ala Phe Val Thr Asp Arg Asp Lys Val Thr Ala Thr Val Ala
                 200                 205                 210

 Gly Leu Thr Leu Leu Ala Val Gly Val Tyr Ser Ala Lys Asn Ala
                 215                 220                 225

 Thr Ala Val Thr Gly Arg Phe Ile Glu Ala Arg Leu Gly Lys Pro
                 230                 235                 240

 Ser Leu Val Arg Glu Thr Ser Arg Ile Thr Val Leu Glu Ala Leu
                 245                 250                 255

 Arg His Pro Ile Gln Val Ser Arg Arg Leu Leu Ser Arg Pro Gln
                 260                 265                 270

 Asp Val Leu Glu Gly Val Val Leu Ser Pro Ser Leu Glu Ala Arg
                 275                 280                 285

 Val Arg Asp Ile Ala Ile Ala Thr Arg Asn Thr Lys Lys Asn Arg
                 290                 295                 300

 Gly Leu Tyr Arg His Ile Leu Leu Tyr Gly Pro Pro Gly Thr Gly
                 305                 310                 315

 Lys Thr Leu Phe Ala Lys Lys Leu Ala Leu His Ser Gly Met Asp
                 320                 325                 330

 Tyr Ala Ile Met Thr Gly Gly Asp Val Ala Pro Met Gly Arg Glu
                 335                 340                 345

 Gly Val Thr Ala Met His Lys Leu Phe Asp Trp Ala Asn Thr Ser
                 350                 355                 360

 Arg Arg Gly Leu Leu Leu Phe Met Asp Glu Ala Asp Ala Phe Leu
                 365                 370                 375

 Arg Lys Arg Ala Thr Glu Glu Ile Ser Lys Asp Leu Arg Ala Thr
                 380                 385                 390

 Leu Asn Ala Phe Leu Tyr His Met Gly Gln His Ser Asn Lys Phe
                 395                 400                 405

 Met Leu Val Leu Ala Ser Asn Leu Pro Glu Gln Phe Asp Cys Ala
                 410                 415                 420

 Ile Asn Ser Arg Ile Asp Val Met Val His Phe Asp Leu Pro Gln
                 425                 430                 435

 Gln Glu Glu Arg Glu Arg Leu Val Arg Leu His Phe Asp Asn Cys
                 440                 445                 450

 Val Leu Lys Pro Ala Thr Glu Gly Lys Arg Arg Leu Lys Leu Ala
                 455                 460                 465

 Gln Phe Asp Tyr Gly Arg Lys Cys Ser Glu Val Ala Arg Leu Thr
                 470                 475                 480

 Glu Gly Met Ser Gly Arg Glu Ile Ala Gln Leu Ala Val Ser Trp
                 485                 490                 495

 Gln Ala Thr Ala Tyr Ala Ser Lys Asp Gly Val Leu Thr Glu Ala
                 500                 505                 510

 Met Met Asp Ala Cys Val Gln Asp Ala Val Gln Gln Tyr Arg Gln
                 515                 520                 525

 Lys Met Arg Trp Leu Lys Ala Glu Gly Pro Gly Arg Gly Val Glu
                 530                 535                 540

 His Pro Leu Ser Gly Val Gln Gly Glu Thr Leu Thr Ser Trp Ser
                 545                 550                 555

 Leu Ala Thr Asp Pro Ser Tyr Pro Cys Leu Ala Gly Pro Cys Thr
                 560                 565                 570

 Phe Arg Ile Cys Ser Trp Met Gly Thr Gly Leu Cys Pro Gly Pro
                 575                 580                 585

 Leu Ser Pro Arg Met Ser Cys Gly Gly Gly Arg Pro Phe Cys Pro
                 590                 595                 600

 Pro Gly His Pro Leu Leu
                 605

<210> 3942
<211> 1845
<212> DNA
<213> Homo sapien

<400> 3942
 agctgacaca accaagacga gtctcagtgt ctagggaagc ttggggttct 50

 gctcctttta cttcaggcga acctgaactt taatgcaatt ttgaagcatg 100

 ccctgaatag attcagtcat tatcaagtca aactaaaaac ggtgaaaggt 150

 tgcgactatt accaaataga agacaatgag aagtcatacc ataacaatga 200

 cgacaacttc agtcagcagc tggccttact cctcccacag aatgcgcttt 250

 ataaccaatc atagcgacca accgccacaa aacttctcag caacaccaaa 300

 tgttactacc tgtcccatgg atgaaaaatt gctatctact gtgttaacca 350

 catcctactc tgttattttc atcgtgggac tggttgggaa cataatcgcc 400

 ctctatgtat ttctgggtat tcaccgtaaa agaaattcca ttcaaattta 450

 tctacttaac gtagccattg cagacctcct actcatcttc tgcctccctt 500

 tccgaataat gtatcatatt aaccaaaaca agtggacact aggtgtgatt 550

 ctgtgcaagg ttgtgggaac actgttttat atgaacatgt acattagcat 600

 tattttgctt ggattcatca gtttggatcg ctatataaaa attaatcggt 650

 ctatacagca acggaaggca ataacaacca aacaaagtat ttatgtctgt 700

 tgtatagtat ggatgcttgc tcttggtgga ttcctaacta tgattatttt 750

 aacacttaag aaaggagggc ataattccac aatgtgtttc cattacagag 800

 ataagcataa cgcaaaagga gaagccattt ttaacttcat tcttgtggta 850

 atgttctggc taattttctt actaataatc ctttcatata ttaagattgg 900

 gaagaatcta ttgaggattt ctaaaaggag gtcaaaattt cctaattctg 950

 gtaaatatgc cactacagct cgtaactcct ttattgtact tatcattttt 1000

 actatatgtt ttgttcccta tcatgccttt cgattcatct acatttcttc 1050

 acagctaaat gtatcatctt gctactggaa agaaattgtt cacaaaacca 1100

 atgagatcat gctggttctc tcatctttca atagttgctt agatccagtc 1150

 atgtatttcc tgatgtccag taacattcgc aaaataatgt gccaacttct 1200

 ttttagacga tttcaaggtg aaccaagtag gagtgaaagc acttcagaat 1250

 ttaaaccagg atactccctg catgatacat ctgtggcagt gaaaatacag 1300

 tctagttcta aaagtacttg aggtaaacat actaaaatga attatataat 1350

 gcagcctctt aattctttga agaactaaaa aattaggaaa caagttctag 1400

 catttacaaa actcagatct caaagctctg cttgtatttg tgatatttca 1450

 tttgcttaac tgtaaaccat ttcaaggtac tatcttttaa atctgtatgt 1500

 aaaatctttt caaaatacat ttttaagcta atactcttaa catagattat 1550

 gaagttaagt gaaatttatg gctctaacag caaaataatt aaagtgccat 1600

 agtttctcaa gtgactaaag tagttattaa aatcaagcac ttgatactaa 1650

 tttgaagtgt gtttaaaagt aaatgatttg ggaactgaca atgtgtcaga 1700

 aaatatatgt tcatttatca ttttaaaatc ttgtataatt tgccactgta 1750

 ttcatttatg cctaaatctc tataacagat gaaaagataa ttaataaaat 1800

 cctaattaaa aaataaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1845

<210> 3943
<211> 381
<212> PRT
<213> Homo sapien

<400> 3943
 Met Arg Ser His Thr Ile Thr Met Thr Thr Thr Ser Val Ser Ser
   1               5                  10                  15

 Trp Pro Tyr Ser Ser His Arg Met Arg Phe Ile Thr Asn His Ser
                  20                  25                  30

 Asp Gln Pro Pro Gln Asn Phe Ser Ala Thr Pro Asn Val Thr Thr
                  35                  40                  45

 Cys Pro Met Asp Glu Lys Leu Leu Ser Thr Val Leu Thr Thr Ser
                  50                  55                  60

 Tyr Ser Val Ile Phe Ile Val Gly Leu Val Gly Asn Ile Ile Ala
                  65                  70                  75

 Leu Tyr Val Phe Leu Gly Ile His Arg Lys Arg Asn Ser Ile Gln
                  80                  85                  90

 Ile Tyr Leu Leu Asn Val Ala Ile Ala Asp Leu Leu Leu Ile Phe
                  95                 100                 105

 Cys Leu Pro Phe Arg Ile Met Tyr His Ile Asn Gln Asn Lys Trp
                 110                 115                 120

 Thr Leu Gly Val Ile Leu Cys Lys Val Val Gly Thr Leu Phe Tyr
                 125                 130                 135

 Met Asn Met Tyr Ile Ser Ile Ile Leu Leu Gly Phe Ile Ser Leu
                 140                 145                 150

 Asp Arg Tyr Ile Lys Ile Asn Arg Ser Ile Gln Gln Arg Lys Ala
                 155                 160                 165

 Ile Thr Thr Lys Gln Ser Ile Tyr Val Cys Cys Ile Val Trp Met
                 170                 175                 180

 Leu Ala Leu Gly Gly Phe Leu Thr Met Ile Ile Leu Thr Leu Lys
                 185                 190                 195

 Lys Gly Gly His Asn Ser Thr Met Cys Phe His Tyr Arg Asp Lys
                 200                 205                 210

 His Asn Ala Lys Gly Glu Ala Ile Phe Asn Phe Ile Leu Val Val
                 215                 220                 225

 Met Phe Trp Leu Ile Phe Leu Leu Ile Ile Leu Ser Tyr Ile Lys
                 230                 235                 240

 Ile Gly Lys Asn Leu Leu Arg Ile Ser Lys Arg Arg Ser Lys Phe
                 245                 250                 255

 Pro Asn Ser Gly Lys Tyr Ala Thr Thr Ala Arg Asn Ser Phe Ile
                 260                 265                 270

 Val Leu Ile Ile Phe Thr Ile Cys Phe Val Pro Tyr His Ala Phe
                 275                 280                 285

 Arg Phe Ile Tyr Ile Ser Ser Gln Leu Asn Val Ser Ser Cys Tyr
                 290                 295                 300

 Trp Lys Glu Ile Val His Lys Thr Asn Glu Ile Met Leu Val Leu
                 305                 310                 315

 Ser Ser Phe Asn Ser Cys Leu Asp Pro Val Met Tyr Phe Leu Met
                 320                 325                 330

 Ser Ser Asn Ile Arg Lys Ile Met Cys Gln Leu Leu Phe Arg Arg
                 335                 340                 345

 Phe Gln Gly Glu Pro Ser Arg Ser Glu Ser Thr Ser Glu Phe Lys
                 350                 355                 360

 Pro Gly Tyr Ser Leu His Asp Thr Ser Val Ala Val Lys Ile Gln
                 365                 370                 375

 Ser Ser Ser Lys Ser Thr
                 380

<210> 3944
<211> 1106
<212> DNA
<213> Homo sapien

<400> 3944
 ctgggagagt gtccgttgct tcccgtccgt gtcgcggccc tgcggttggc 50

 ggcctcctcg tggagcggag caagggtagg ccccacgtgg cgtctttgcc 100

 cggctccaag atggacggca gcggggactg ggaggctgct ctgggggagc 150

 acgtggcgcc ctgctcgcct gctcccgggg cagctgggat ggtggcggag 200

 tccggaggcc tcctgccgcc gtcgggcagg gaggccggcg gaggcggggc 250

 tgtggccgcc cccgagaggc gcccaggcgg cggcggcggc ggcccagctt 300

 cttctttcct cgcacagcca ggcggcccct gctcgagtcc cgcgtcgcca 350

 tggccgcggt tcccgagttg ctgcagcagc aggaggagga ccgcagcaag 400

 gtgaggtcct cccagcctca gactcctggg cgggcggccc tgcgagctcc 450

 ggggtcgctg cattctttcc cttgcgcgtc cataggccgt ggctgctcgc 500

 cgccatcccc agcgcgggaa gcacccgtga gacccgggcg gcccctctcc 550

 ctggtcttca ctgaaggctg ccccggggaa tccctgtgga tgtcccggat 600

 tctattagga cagaaccaga gacgcgggac cttagcccca gctcaggcgc 650

 cggtgccgag cggacttgga gagatgatct ctggagaccc cggaatgttc 700

 tttttaaaac tttcctcggc ttcgtggtga ccagtaggtg aacgtgaaat 750

 tgacttaaca tgcgacagac cagtttggtt tgttgccccc aaaataccct 800

 ccttcccccc accttttact gagaagactt ttttgggggg ggggcccaaa 850

 caacttggga aattgcatca agcgtccgaa catgctgctt acaactttag 900

 aaacgcaaaa tgcgttgttg tgggagttgt gtaattttta gtaggtgctc 950

 aaatacttgc tgaacttggt gtctattttt aagtcttgcc cattgatgta 1000

 aactgtccct aggtcacgtg tatcttgagg tctaaaagat tatttatgca 1050

 ataaattgaa attcccatag ccaattaaag attcaaaaaa aaaaaaaaaa 1100

 aaaaaa 1106

<210> 3945
<211> 126
<212> PRT
<213> Homo sapien

<400> 3945
 Met Ala Ala Val Pro Glu Leu Leu Gln Gln Gln Glu Glu Asp Arg
   1               5                  10                  15

 Ser Lys Val Arg Ser Ser Gln Pro Gln Thr Pro Gly Arg Ala Ala
                  20                  25                  30

 Leu Arg Ala Pro Gly Ser Leu His Ser Phe Pro Cys Ala Ser Ile
                  35                  40                  45

 Gly Arg Gly Cys Ser Pro Pro Ser Pro Ala Arg Glu Ala Pro Val
                  50                  55                  60

 Arg Pro Gly Arg Pro Leu Ser Leu Val Phe Thr Glu Gly Cys Pro
                  65                  70                  75

 Gly Glu Ser Leu Trp Met Ser Arg Ile Leu Leu Gly Gln Asn Gln
                  80                  85                  90

 Arg Arg Gly Thr Leu Ala Pro Ala Gln Ala Pro Val Pro Ser Gly
                  95                 100                 105

 Leu Gly Glu Met Ile Ser Gly Asp Pro Gly Met Phe Phe Leu Lys
                 110                 115                 120

 Leu Ser Ser Ala Ser Trp
                 125

<210> 3946
<211> 2464
<212> DNA
<213> Homo sapien

<400> 3946
 atggccgacc cgcaggctgg ctccgcggcc ggggactggg agatcgatgt 50

 cgagagcctg gagctggaag aggacgtctg cggggcgccg cggtccacgc 100

 cccccgggcc cagcccgccg ccggcggacg gggactgcga ggacgacgaa 150

 gatgacgacg gggtggacga agacgcggaa gaagagggcg acggcgagga 200

 ggcaggcgcg tcccccggga tgcccggcca gccggagcag cgggggggac 250

 cgcagccgag gccgccgctc gcgcctcagg cctcacccgc cggcaccggt 300

 ccccgagagc gctgcactcc cgcgggcggc ggcgcggagc cgcgcaagct 350

 gagccgcacg cccaagtgcg cgcgctgccg caaccacggc gtggtgtcct 400

 gcctgaaggg ccacaagcgc ttctgtcgct ggcgcgactg ccagtgcgcc 450

 aactgcctgc tggtggtgga gcggcagcgc gtcatggccg cccaggtggc 500

 gctccggagg cagcaggcca ccgaggacaa gaaggggctt tccgggaaac 550

 agaataattt cgagcgcaaa gctgtgtacc agaggcaagt cagagccccc 600

 agtttgctgg ccaaaagcat tttagaagtt ctccttggat tattctacag 650

 ctattatgtg tacataatga accatcttta gaaaataaaa gtgacatcag 700

 ctctaggtat agatatattt tttaataatg aaaaaagatg acatggataa 750

 taataaaaca ttgattgata caagataaat agtcttgtct cttaatgcgt 800

 agggggcctg ggaagaatat taaaatttta atcaataaag tatgtctgtt 850

 gaagcaagca agcaaacaaa tccataacaa ccacaacaag caacaagaac 900

 aagaacaaca acaagaagaa gttgcagtat ggatatcttt caccctccca 950

 ggaaactctt tcaaacctaa tctggacttt tgcatctgta taaaaatatc 1000

 agtgagatgg aactgtaaat aattgttctg ctgatctgta gtggttgctg 1050

 ttaccttctg ggtttccaca tttttattcc gtagatgtta atctctttca 1100

 tgtgcaatct ttgcttcttg taggctatcg ccccattcca gcggagactt 1150

 atgtaggagg gaccttccct ctacctcccc cagttagtga caggatgagg 1200

 aaaagaagag cctttgctga taaagagttg gagaacatta tgctggagag 1250

 agaatataaa gaaagggaga tgttggaaac ttctcaagct gctgctctgt 1300

 ttctgcccaa ccgcatggtg cctggacctg actacaattc ctacaaaagt 1350

 gcctacagcc ccagcccagt ggaaccacca agcaaggact tctgtaattt 1400

 tttgcccacc tgccttgatt taaccatgca gtattcaggg tctgggaata 1450

 tggaactaat ttcttctaat gtcagcgtgg gcacaactta tagacagtat 1500

 cccttgtcct caagattttt agtttggccc aagtgtggcc ccattagcga 1550

 caccctcctc taccagcaat gcctgctaaa tgccaccacc tcagttcaag 1600

 ccctgaagca tggggccagc tgggacttga agggagcacg agtccaggat 1650

 ggactcagtg cagagcagga catgatgcca tcgaaattgg aaggttccct 1700

 ggtgctgcct cacactcctg agatccagac cacgagaagt gaccttcagg 1750

 gtcatcaggc tgtcccagag aggtccgcgt tctccccacc ccgacggaat 1800

 ttctctccca ttgttgacac ggactccctg gcagctcaag ggcatgtctt 1850

 aacgaagatc agcaaagaaa acaccaggca ccctctgcca cttagacata 1900

 atccattcca ctcattattc cagcaaacac ttactgacaa atcgggtcct 1950

 gagttgaaaa caccatttgt caaagaggcc tttgaagaga cccctaagaa 2000

 acacagagag tgtttagtta aggacaacca gaagtacaca tttacaatag 2050

 atagatgtgc aaaagacctt tttgtagcca aacaagttgg aacaaaactc 2100

 tcggtgaatg aaccactgtc attttctgtt gagtctattc ttaagaggcc 2150

 ttcatctgcc atcactcgtg tctctcagtg aaaggctgct taaacagaaa 2200

 gctggatttt ctgcagtctt agagcattat agccatttgc tacttttttt 2250

 aaaagttaag atgtttgtgt aaagaaattt ctaatgtaaa gatgatgatt 2300

 ttgaaaaatt ttatatattc ctaatatgca tgtacttttt cttatcacat 2350

 atatttaaac ttacagatgg aaattgccca atgtgcaaat tgttaagtac 2400

 cacactttac acagcatttc aaaaagcaat aaaattgaca ctgtcttctc 2450

 aaagacccaa aaaa 2464

<210> 3947
<211> 226
<212> PRT
<213> Homo sapien

<400> 3947
 Met Ala Asp Pro Gln Ala Gly Ser Ala Ala Gly Asp Trp Glu Ile
   1               5                  10                  15

 Asp Val Glu Ser Leu Glu Leu Glu Glu Asp Val Cys Gly Ala Pro
                  20                  25                  30

 Arg Ser Thr Pro Pro Gly Pro Ser Pro Pro Pro Ala Asp Gly Asp
                  35                  40                  45

 Cys Glu Asp Asp Glu Asp Asp Asp Gly Val Asp Glu Asp Ala Glu
                  50                  55                  60

 Glu Glu Gly Asp Gly Glu Glu Ala Gly Ala Ser Pro Gly Met Pro
                  65                  70                  75

 Gly Gln Pro Glu Gln Arg Gly Gly Pro Gln Pro Arg Pro Pro Leu
                  80                  85                  90

 Ala Pro Gln Ala Ser Pro Ala Gly Thr Gly Pro Arg Glu Arg Cys
                  95                 100                 105

 Thr Pro Ala Gly Gly Gly Ala Glu Pro Arg Lys Leu Ser Arg Thr
                 110                 115                 120

 Pro Lys Cys Ala Arg Cys Arg Asn His Gly Val Val Ser Cys Leu
                 125                 130                 135

 Lys Gly His Lys Arg Phe Cys Arg Trp Arg Asp Cys Gln Cys Ala
                 140                 145                 150

 Asn Cys Leu Leu Val Val Glu Arg Gln Arg Val Met Ala Ala Gln
                 155                 160                 165

 Val Ala Leu Arg Arg Gln Gln Ala Thr Glu Asp Lys Lys Gly Leu
                 170                 175                 180

 Ser Gly Lys Gln Asn Asn Phe Glu Arg Lys Ala Val Tyr Gln Arg
                 185                 190                 195

 Gln Val Arg Ala Pro Ser Leu Leu Ala Lys Ser Ile Leu Glu Val
                 200                 205                 210

 Leu Leu Gly Leu Phe Tyr Ser Tyr Tyr Val Tyr Ile Met Asn His
                 215                 220                 225

 Leu


<210> 3948
<211> 703
<212> DNA
<213> Homo sapien

<400> 3948
 cagatttaaa gagtttcttc ctgttaattc gaagctcact gtgcctcttg 50

 tttccgaggg aagaaggact gattaagtca tctaaatgga tgcaatactg 100

 aattacaggt cagaagatac tgaagattac tacacattac tgggatgtga 150

 tgaactatct tcggttgaac aaatcctggc agaatttaaa gtcagagctc 200

 tggaatgtca cccagacaag catcctgaaa accccaaagc tgtggagact 250

 tttcagaaac tgcagaaggc aaaggagatt ctgaccaatg aagagagtcg 300

 agcccgctat gaccactggc gaaggagcca gatgtcgatg ccattccagc 350

 agtgggaagc tttgaatgac tcagtgaaga cggtgggttt ctcgctgggt 400

 gcgacgtgaa tttgtgaagc tcaggatgcc catggattag actcatgtag 450

 tagcttaaag agtcattagg cgataggagg gagaaaacca agaagttagc 500

 agagtctgga tataattcag tgtccgtaaa tcccatgaag agaagctcat 550

 cagaataaag gcaatgaatt tgtgccagaa gagcctgtga ctacatttct 600

 ttcaatctct ttggctgttt gtttcagtat acacactccc tgttattgct 650

 tactatttta tgagctctaa taaatgtact tctcaagttg ctcatgaaaa 700

 aaa 703

<210> 3949
<211> 107
<212> PRT
<213> Homo sapien

<400> 3949
 Met Asp Ala Ile Leu Asn Tyr Arg Ser Glu Asp Thr Glu Asp Tyr
   1               5                  10                  15

 Tyr Thr Leu Leu Gly Cys Asp Glu Leu Ser Ser Val Glu Gln Ile
                  20                  25                  30

 Leu Ala Glu Phe Lys Val Arg Ala Leu Glu Cys His Pro Asp Lys
                  35                  40                  45

 His Pro Glu Asn Pro Lys Ala Val Glu Thr Phe Gln Lys Leu Gln
                  50                  55                  60

 Lys Ala Lys Glu Ile Leu Thr Asn Glu Glu Ser Arg Ala Arg Tyr
                  65                  70                  75

 Asp His Trp Arg Arg Ser Gln Met Ser Met Pro Phe Gln Gln Trp
                  80                  85                  90

 Glu Ala Leu Asn Asp Ser Val Lys Thr Val Gly Phe Ser Leu Gly
                  95                 100                 105

 Ala Thr


<210> 3950
<211> 2404
<212> DNA
<213> Homo sapien

<400> 3950
 cccaaagtag gctaggccta cggaagctgg gtcttcttgc tgtgaggtcg 50

 cgttccccag tgttacggag ggtccttgag gcaggagtga aaattgggtc 100

 tgggggttag tcctggggtg gaggtctggg cacgccgggt cggaccccct 150

 ccatcttcgg ttttgcacac cccgctttcc agcgcggagt cgcggcgggt 200

 agggcggcgt cgcgtgcgtg acgtcatcca gcggcgcctc gcgaggctcc 250

 agtggccttg acctcccgcg gcgtgggagg ctgcgcggcg atgctgcagt 300

 tcgtccgggc cggggcgcgg gcctggcttc ggcctaccgg cagccagggc 350

 ctgagttccc tggcggaaga ggcagcgcgt gcgaccgaga acccggagca 400

 ggtggcgagc gagggtctcc cggagcccgt gctgcgcaaa gtcgagctcc 450

 cggtacccac tcatcgacgc ccagtgcagg cctgggtcga gtccttgcgg 500

 ggcttcgagc aggagcgcgt gggcctggcc gacctgcacc ccgatgtttt 550

 cgccaccgcg cccaggctgg acatactgca ccaggttgct atgtggcaga 600

 agaacttcaa gagaattagc tatgccaaga ccaagacgag agccgaggtg 650

 cggggcggtg gccggaagcc ttggccgcag aaaggcactg ggcgggcccg 700

 gcatggcagc atccgctctc cgctctggcg aggaggaggt gttgcccatg 750

 gcccccgggg ccccacaagt tactactaca tgctgcccat gaaggtgcgg 800

 gcgctgggtc tcaaagtggc actgaccgtc aagctggccc aggacgacct 850

 gcacatcatg gactccctag agctgcccac cggagaccca cagtacctga 900

 cagagctggc gcactaccgc cgctgggggg actccgtact cctcgtggac 950

 ttaacacacg aggagatgcc acagagcatc gtggaggcca cctctaggct 1000

 taagaccttc aacttgatcc cggctgttgg tgagcaaaga gcccaggccc 1050

 ctagagtgcg catgtgcagg ctccgctgtt agaatcacag cggttcaaat 1100

 ccggcatctg gtcgctgagt ggcctcaggc agtgaccacg ctcccggacc 1150

 caaccttcag cttgcccaaa gcaataatct ttcctaaaga agtgcttggc 1200

 tggggatggt ggctcacgct tgtaatccca gtactttggg aggccaaggc 1250

 agtctgggca atatagtgag gctcccatct gtactaaaaa taaaaaagtt 1300

 aggcgtggcg atgtgcacct gtagtcccag ctactcgggg gctgagccag 1350

 gcggatagct tgagctcagg gggccaaggc tgcagtgagt catgatcgca 1400

 ccactgcacc caaacctggg gagagagcta gactcttgtc tcaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaag ctccaaagtc acctctgtca aagccacagt 1500

 ctgttccttc cacagccaca agatggcgac atgagcctaa gtcaagtcct 1550

 gtccctcaac ccacgcccct cgctggcttc cccacctctc tcaggatgaa 1600

 agcccaagtc atcagggtgg cacgtcaggc cctgcacgat gtgccccgtc 1650

 acctccctgc cctcccgtca tttgccctgg gtctccccca ccagaatggg 1700

 agccaggagt cccagccagg cacaggaccg agcctggctc tcggtcagca 1750

 ggtgatgagc tgggagcagc tccttggcca gaggcttaca ggcaacaagc 1800

 ggccaggcag ggtctggccc cgggctgctg ggctcacaaa gtcacactag 1850

 accacagtga cgatctctgt aagcacaaag ggactccgat gtgggtgggg 1900

 tgaggagaga ggcagccccg gcctgaccgg ccccccgccc cgcccccacc 1950

 ccgcccccag gcctaaatgt gcacagcatg ctcaagcacc agacgctggt 2000

 cctgacgctg cccaccgtcg ccttcctgga ggacaagctg ctctggcagg 2050

 actcacgtta cagacccctc taccccttca gcctgcccta cagcgacttc 2100

 ccccgacccc taccccacgc tacccagggc ccagcggcca ccccgtacca 2150

 ctgttgatgt gaagcacctc ttctgagcca ggccgagccc ctggccgact 2200

 tgggagcctc aggcccacgc ccacccttcg aggaaggtgt cacctggacc 2250

 ccttcattcc acggaggaag ctgaggccac agggagcggc catcgccatt 2300

 gggaaggggc gactccacgg aaagcccaga cgggcttctg catccattcc 2350

 ctctttttgt ttttaaaata aattgtattt ttgaatcaag gaggataaag 2400

 ataa 2404

<210> 3951
<211> 263
<212> PRT
<213> Homo sapien

<400> 3951
 Met Leu Gln Phe Val Arg Ala Gly Ala Arg Ala Trp Leu Arg Pro
   1               5                  10                  15

 Thr Gly Ser Gln Gly Leu Ser Ser Leu Ala Glu Glu Ala Ala Arg
                  20                  25                  30

 Ala Thr Glu Asn Pro Glu Gln Val Ala Ser Glu Gly Leu Pro Glu
                  35                  40                  45

 Pro Val Leu Arg Lys Val Glu Leu Pro Val Pro Thr His Arg Arg
                  50                  55                  60

 Pro Val Gln Ala Trp Val Glu Ser Leu Arg Gly Phe Glu Gln Glu
                  65                  70                  75

 Arg Val Gly Leu Ala Asp Leu His Pro Asp Val Phe Ala Thr Ala
                  80                  85                  90

 Pro Arg Leu Asp Ile Leu His Gln Val Ala Met Trp Gln Lys Asn
                  95                 100                 105

 Phe Lys Arg Ile Ser Tyr Ala Lys Thr Lys Thr Arg Ala Glu Val
                 110                 115                 120

 Arg Gly Gly Gly Arg Lys Pro Trp Pro Gln Lys Gly Thr Gly Arg
                 125                 130                 135

 Ala Arg His Gly Ser Ile Arg Ser Pro Leu Trp Arg Gly Gly Gly
                 140                 145                 150

 Val Ala His Gly Pro Arg Gly Pro Thr Ser Tyr Tyr Tyr Met Leu
                 155                 160                 165

 Pro Met Lys Val Arg Ala Leu Gly Leu Lys Val Ala Leu Thr Val
                 170                 175                 180

 Lys Leu Ala Gln Asp Asp Leu His Ile Met Asp Ser Leu Glu Leu
                 185                 190                 195

 Pro Thr Gly Asp Pro Gln Tyr Leu Thr Glu Leu Ala His Tyr Arg
                 200                 205                 210

 Arg Trp Gly Asp Ser Val Leu Leu Val Asp Leu Thr His Glu Glu
                 215                 220                 225

 Met Pro Gln Ser Ile Val Glu Ala Thr Ser Arg Leu Lys Thr Phe
                 230                 235                 240

 Asn Leu Ile Pro Ala Val Gly Glu Gln Arg Ala Gln Ala Pro Arg
                 245                 250                 255

 Val Arg Met Cys Arg Leu Arg Cys
                 260

<210> 3952
<211> 1188
<212> DNA
<213> Mus musculus

<400> 3952
 atggatgaag aacctgaaag aactaagcga tgggaaggag gctatgaaag 50

 aacatgggag attcttaaag aagatgaatc tggatcactt aaagctacaa 100

 tagaagacat tctattcaag gcaaagagaa aaagagtatt tgagcaccat 150

 ggacaagttc gacttggaat gatgcgccac ctttatgtgg tagtagatgg 200

 atcaagaaca atggaagacc aagatttaaa gcctaataga ctgacgtgta 250

 ctttaaagtt gttggaatac tttgtagagg aatattttga tcaaaatcct 300

 attagtcaga ttggaataat tgtaactaag agtaaaagag ctgaaaaatt 350

 gactgaactt tcaggaaacc caagaaaaca tataacgtct ttgaagaaag 400

 ctgtggatat gacctgccat ggagagccat ctctttataa ttccctaagc 450

 atagctatgc agactctaaa acacatgcct ggacatacaa gtcgagaagt 500

 actaatcatc tttagcagcc ttacaacttg cgatccatct aatatttatg 550

 atctaatcaa gaccctaaag gcagctaaaa ttagagtatc tgttattgga 600

 ttgtctgcag aagttcgcgt ttgcactgta cttgctcgtg aaactggtgg 650

 cacgtaccat gttattttag atgaaagcca ttacaaagag ttgctcacac 700

 atcatgttag tcctcctcct gctagctcaa gttctgaatg ctcacttatt 750

 cgtatgggat ttcctcagca caccattgct tctttatctg accaggatgc 800

 aaaaccctct ttcagcatgg cgcatttgga tggcaatact gagccagggc 850

 ttacattagg aggctatttc tgcccacagt gtcgggcaaa gtactgtgag 900

 ctacctgttg aatgtaaaat ctgtggtctt actttggtgt ctgctcccca 950

 cttggcacgg tcttaccatc atttgtttcc tttggatgct tttcaagaaa 1000

 ttcccctaga agaatataat ggagaaagat tttgttatgg atgtcagggg 1050

 gaattgaaag accaacatgt ttatgtttgt gctgtgtgcc aaaatgtttt 1100

 ctgtgtggac tgtgatgttt ttgttcatga ttctctacac tgttgccctg 1150

 gctgtattca taagattcca gctccttcag gtgtttga 1188

<210> 3953
<211> 395
<212> PRT
<213> Mus musculus

<400> 3953
 Met Asp Glu Glu Pro Glu Arg Thr Lys Arg Trp Glu Gly Gly Tyr
   1               5                  10                  15

 Glu Arg Thr Trp Glu Ile Leu Lys Glu Asp Glu Ser Gly Ser Leu
                  20                  25                  30

 Lys Ala Thr Ile Glu Asp Ile Leu Phe Lys Ala Lys Arg Lys Arg
                  35                  40                  45

 Val Phe Glu His His Gly Gln Val Arg Leu Gly Met Met Arg His
                  50                  55                  60

 Leu Tyr Val Val Val Asp Gly Ser Arg Thr Met Glu Asp Gln Asp
                  65                  70                  75

 Leu Lys Pro Asn Arg Leu Thr Cys Thr Leu Lys Leu Leu Glu Tyr
                  80                  85                  90

 Phe Val Glu Glu Tyr Phe Asp Gln Asn Pro Ile Ser Gln Ile Gly
                  95                 100                 105

 Ile Ile Val Thr Lys Ser Lys Arg Ala Glu Lys Leu Thr Glu Leu
                 110                 115                 120

 Ser Gly Asn Pro Arg Lys His Ile Thr Ser Leu Lys Lys Ala Val
                 125                 130                 135

 Asp Met Thr Cys His Gly Glu Pro Ser Leu Tyr Asn Ser Leu Ser
                 140                 145                 150

 Ile Ala Met Gln Thr Leu Lys His Met Pro Gly His Thr Ser Arg
                 155                 160                 165

 Glu Val Leu Ile Ile Phe Ser Ser Leu Thr Thr Cys Asp Pro Ser
                 170                 175                 180

 Asn Ile Tyr Asp Leu Ile Lys Thr Leu Lys Ala Ala Lys Ile Arg
                 185                 190                 195

 Val Ser Val Ile Gly Leu Ser Ala Glu Val Arg Val Cys Thr Val
                 200                 205                 210

 Leu Ala Arg Glu Thr Gly Gly Thr Tyr His Val Ile Leu Asp Glu
                 215                 220                 225

 Ser His Tyr Lys Glu Leu Leu Thr His His Val Ser Pro Pro Pro
                 230                 235                 240

 Ala Ser Ser Ser Ser Glu Cys Ser Leu Ile Arg Met Gly Phe Pro
                 245                 250                 255

 Gln His Thr Ile Ala Ser Leu Ser Asp Gln Asp Ala Lys Pro Ser
                 260                 265                 270

 Phe Ser Met Ala His Leu Asp Gly Asn Thr Glu Pro Gly Leu Thr
                 275                 280                 285

 Leu Gly Gly Tyr Phe Cys Pro Gln Cys Arg Ala Lys Tyr Cys Glu
                 290                 295                 300

 Leu Pro Val Glu Cys Lys Ile Cys Gly Leu Thr Leu Val Ser Ala
                 305                 310                 315

 Pro His Leu Ala Arg Ser Tyr His His Leu Phe Pro Leu Asp Ala
                 320                 325                 330

 Phe Gln Glu Ile Pro Leu Glu Glu Tyr Asn Gly Glu Arg Phe Cys
                 335                 340                 345

 Tyr Gly Cys Gln Gly Glu Leu Lys Asp Gln His Val Tyr Val Cys
                 350                 355                 360

 Ala Val Cys Gln Asn Val Phe Cys Val Asp Cys Asp Val Phe Val
                 365                 370                 375

 His Asp Ser Leu His Cys Cys Pro Gly Cys Ile His Lys Ile Pro
                 380                 385                 390

 Ala Pro Ser Gly Val
                 395

<210> 3954
<211> 570
<212> DNA
<213> Homo sapien

<400> 3954
 ggccgtgcct tctctcgctt cggactgcgc aacgctgcgc tctgggctga 50

 caggcggata aaacggtccc atcaagactg agaaaaagca caccagctat 100

 tggcacagcg tgggcagtgg ggcctacagg atgactgact tagtctacag 150

 agatcccggc gtacttaagc agatgaagac tcttaagatg acagaaggtg 200

 atttttctgg tgatcgagga cttccggggt aatgacagtg atgaaatgca 250

 ggggacctgg ttgcccccaa gtttcctggc agtgtgtgat actgaggagg 300

 tgagcttgtt tctggagctg tgctttaaga ttcatgttac atgtaaagct 350

 gtcctcattt gtgactatgg acctatggag ttgggacaat ctctatggga 400

 agcagaaggc aaggaccccg gtcattttag gtagaaacaa cagcatgcta 450

 atgcaaaaaa ttatgcagtg tgctactgaa cttcagaggt gatcaataaa 500

 agaagaataa aaagactaat aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 550

 aaaaaaaaaa aaaaaaaaaa 570

<210> 3955
<211> 62
<212> PRT
<213> Homo sapien

<400> 3955
 Met Gln Gly Thr Trp Leu Pro Pro Ser Phe Leu Ala Val Cys Asp
   1               5                  10                  15

 Thr Glu Glu Val Ser Leu Phe Leu Glu Leu Cys Phe Lys Ile His
                  20                  25                  30

 Val Thr Cys Lys Ala Val Leu Ile Cys Asp Tyr Gly Pro Met Glu
                  35                  40                  45

 Leu Gly Gln Ser Leu Trp Glu Ala Glu Gly Lys Asp Pro Gly His
                  50                  55                  60

 Phe Arg


<210> 3956
<211> 2375
<212> DNA
<213> Homo sapien

<400> 3956
 taatttaaac cagtgtttgt gcggttctga ttcatctgct gtggttcccg 50

 aagcttgaga tctaaggagt acagggtctt ttgtgatgac aatatgacta 100

 atagtaaagg aagatctatt accgataaaa caagtggtgg tccaagtagt 150

 ggaggaggtt ttgtagattg gactttacgt ttaaacacaa ttcaatccga 200

 caagttttta aatttactct tgagtatggt tccagtgatt taccagaaaa 250

 accaagaaga caggcacaaa aaagcaaacg gcatttggca agatggatat 300

 caactgcagt acagactttt agtaatagat ctgagcaaca catggagtat 350

 cacagtttct cagagcagtc ttttcatgcc aataatgggc acgcatcatc 400

 aagctgcagc caaaagtatg atgactatgc caattgtaat tactgtgatg 450

 gaagggagac ttcagaaacc actgccatgt tacaagatga agatatatct 500

 agtgatggtg atgaagatgc tattgtagaa gtgaccccaa aattaccaaa 550

 ggaatccagt ggcatcatgg cattgcaaat acttgtgccc tttttgctag 600

 ctggttttgg aacagtttca gctggcatgg tactggatat agtacagcac 650

 tgggaggtgt tcagaaaagt tacagaagtt ttcattttag tccctgcact 700

 tcttggtctc aaagggaact tggaaatgac attggcatcc agattatcca 750

 ctgcagtaaa tattgggaag atggattcac ccattgaaaa gtggaaccta 800

 ataattggca acttggcttt aaagcaggtt caggcaacag tagtgggttt 850

 tctagcagct gtggcagcaa ttatattggg ctggattcca gaaggaaaat 900

 attaccttga tcattccata cttctgtgct ctagcagtgt ggcaactgcc 950

 ttcattgcat ctcttctgca gggaataata atggttgggg ttatcgttgg 1000

 ttcaaagaag actggtataa atcctgataa tgttgctaca cccattgctg 1050

 ctagttttgg cgaccttata actcttgcca tattggcttg gataagtcag 1100

 ggcttatact cctgtcttga gacctattac tacatttctc cattagttgg 1150

 tgtatttttc ttggctctaa cccctatttg gattataata gctgccaaac 1200

 atccagccac aagaacagtt ctccactcag gctgggagcc tgtcataaca 1250

 gctatggtta taagtagcat tgggggcctt attctggaca caactgtatc 1300

 agacccaaac ttggttggga ttgttgttta cacgccagtt attaatggta 1350

 ttggtggtaa tttggtggcc attcaggcta gcaggatttc tacctacctc 1400

 catttacata gcattccagg agaattgcct gatgaaccca aaggttgtta 1450

 ctacccattt agaactttct ttggtccagg agtaaataat aagtctgctc 1500

 aagttctact gcttttagtg attcctggac atttaatttt cctctacact 1550

 attcatttga tgaaaagtgg tcatacttct ttaactataa tcttcatagt 1600

 agtgtattta tttggcgctg tgttacaggt atttaccttg ctgtggattg 1650

 ctgactggat ggtccatcac ttctggagga aaggaaagga cccggatagt 1700

 ttctccatcc cctacctaac agcattgggt gatctgctcg ggacagctct 1750

 gttagcctta agttttcatt ttctttggct tattggagat cgagatggag 1800

 atgttggaga ctaataaatt ctacaaactg ctctcaagtt accaaggaag 1850

 aaaatacacg acaaccactt atggctcttt ttcaaaactc ttaaatcagt 1900

 agtttgactt ttgccagggt aatcttcagt tggccctgat tcaattaaat 1950

 ggccttaatt tttttttaag gaatttgtgt caaaaccaga atgaagagta 2000

 ttcgtgctgc ttttcataga ataaatgata atttgacata gacatagata 2050

 taagttccag ctctgaaatt aattaggaaa gaatatagga tgtttacagt 2100

 gaataatttt aaaaccacaa acatagcaga aatgtacttt attattaaat 2150

 ttgtaatgca ggattagaag aagcagagct ctagtttagc ctttcttgtc 2200

 tcacagatgt gctgtatccc aggcatacta taaaacgaag agtgcccaac 2250

 caagctttga atcgtattaa caatgcccac ctctatgcta gctgaggata 2300

 aatttaccag ttgctcatat ttaaactgac ctaaatatgt tttgctgagc 2350

 ataagataaa ctcactttta cctcc 2375

<210> 3957
<211> 490
<212> PRT
<213> Homo sapien

<400> 3957
 Met Glu Tyr His Ser Phe Ser Glu Gln Ser Phe His Ala Asn Asn
   1               5                  10                  15

 Gly His Ala Ser Ser Ser Cys Ser Gln Lys Tyr Asp Asp Tyr Ala
                  20                  25                  30

 Asn Cys Asn Tyr Cys Asp Gly Arg Glu Thr Ser Glu Thr Thr Ala
                  35                  40                  45

 Met Leu Gln Asp Glu Asp Ile Ser Ser Asp Gly Asp Glu Asp Ala
                  50                  55                  60

 Ile Val Glu Val Thr Pro Lys Leu Pro Lys Glu Ser Ser Gly Ile
                  65                  70                  75

 Met Ala Leu Gln Ile Leu Val Pro Phe Leu Leu Ala Gly Phe Gly
                  80                  85                  90

 Thr Val Ser Ala Gly Met Val Leu Asp Ile Val Gln His Trp Glu
                  95                 100                 105

 Val Phe Arg Lys Val Thr Glu Val Phe Ile Leu Val Pro Ala Leu
                 110                 115                 120

 Leu Gly Leu Lys Gly Asn Leu Glu Met Thr Leu Ala Ser Arg Leu
                 125                 130                 135

 Ser Thr Ala Val Asn Ile Gly Lys Met Asp Ser Pro Ile Glu Lys
                 140                 145                 150

 Trp Asn Leu Ile Ile Gly Asn Leu Ala Leu Lys Gln Val Gln Ala
                 155                 160                 165

 Thr Val Val Gly Phe Leu Ala Ala Val Ala Ala Ile Ile Leu Gly
                 170                 175                 180

 Trp Ile Pro Glu Gly Lys Tyr Tyr Leu Asp His Ser Ile Leu Leu
                 185                 190                 195

 Cys Ser Ser Ser Val Ala Thr Ala Phe Ile Ala Ser Leu Leu Gln
                 200                 205                 210

 Gly Ile Ile Met Val Gly Val Ile Val Gly Ser Lys Lys Thr Gly
                 215                 220                 225

 Ile Asn Pro Asp Asn Val Ala Thr Pro Ile Ala Ala Ser Phe Gly
                 230                 235                 240

 Asp Leu Ile Thr Leu Ala Ile Leu Ala Trp Ile Ser Gln Gly Leu
                 245                 250                 255

 Tyr Ser Cys Leu Glu Thr Tyr Tyr Tyr Ile Ser Pro Leu Val Gly
                 260                 265                 270

 Val Phe Phe Leu Ala Leu Thr Pro Ile Trp Ile Ile Ile Ala Ala
                 275                 280                 285

 Lys His Pro Ala Thr Arg Thr Val Leu His Ser Gly Trp Glu Pro
                 290                 295                 300

 Val Ile Thr Ala Met Val Ile Ser Ser Ile Gly Gly Leu Ile Leu
                 305                 310                 315

 Asp Thr Thr Val Ser Asp Pro Asn Leu Val Gly Ile Val Val Tyr
                 320                 325                 330

 Thr Pro Val Ile Asn Gly Ile Gly Gly Asn Leu Val Ala Ile Gln
                 335                 340                 345

 Ala Ser Arg Ile Ser Thr Tyr Leu His Leu His Ser Ile Pro Gly
                 350                 355                 360

 Glu Leu Pro Asp Glu Pro Lys Gly Cys Tyr Tyr Pro Phe Arg Thr
                 365                 370                 375

 Phe Phe Gly Pro Gly Val Asn Asn Lys Ser Ala Gln Val Leu Leu
                 380                 385                 390

 Leu Leu Val Ile Pro Gly His Leu Ile Phe Leu Tyr Thr Ile His
                 395                 400                 405

 Leu Met Lys Ser Gly His Thr Ser Leu Thr Ile Ile Phe Ile Val
                 410                 415                 420

 Val Tyr Leu Phe Gly Ala Val Leu Gln Val Phe Thr Leu Leu Trp
                 425                 430                 435

 Ile Ala Asp Trp Met Val His His Phe Trp Arg Lys Gly Lys Asp
                 440                 445                 450

 Pro Asp Ser Phe Ser Ile Pro Tyr Leu Thr Ala Leu Gly Asp Leu
                 455                 460                 465

 Leu Gly Thr Ala Leu Leu Ala Leu Ser Phe His Phe Leu Trp Leu
                 470                 475                 480

 Ile Gly Asp Arg Asp Gly Asp Val Gly Asp
                 485                 490

<210> 3958
<211> 2164
<212> DNA
<213> Homo sapien

<400> 3958
 atttctgcag agacagaaag aaacgcagct cttgacttct tttttgtaaa 50

 cattactgta agagttgtga taacttttta ttctactatg tatatgtatg 100

 gaatagtatt aataaatgaa ctagggaagg atgtaataaa ttagacatct 150

 cttcatttta gagagaagat ggaaacaaca ttgcttttct tttctcaaat 200

 aaatatgtgt gaatcaaaag aaaaaacttt tttcaagtta atacatggtt 250

 caggaaaaga agaaacaagc aaagaagcca aaatcagagc taaggaaaaa 300

 agaaatagac taagtcttct tgtgcagaaa cctgagtttc atgaagacac 350

 ccgctccagt agatctgggc acttggccaa agaaacaaga gtctcccctg 400

 aagaggcagt gaaatggggt gaatcatttg acaaactgct ttcccataga 450

 gatggactag aggcttttac cagatttctt aaaactgaat tcagtgaaga 500

 aaatattgaa ttttggatag cctgtgaaga tttcaagaaa agcaagggac 550

 ctcaacaaat tcaccttaaa gcaaaagcaa tatatgagaa atttatacag 600

 actgatgccc caaaagaggt taaccttgat tttcacacaa aagaagtcat 650

 tacaaacagc atcactcaac ctaccctcca cagttttgat gctgcacaaa 700

 gcagagtgta tcagctcatg gaacaagaca gttatacacg ttttctgaaa 750

 tctgacatct atttagactt gatggaagga agacctcaga gaccaacaaa 800

 tcttaggaga cgatcacgct catttacctg caatgaattc caagatgtac 850

 aatcagacgt tgccatttgg ttataaagaa aattgatttt gctcattttt 900

 atgacaaact tatacatctg cttctaacat atcgcatgtt tatgttaaga 950

 tttggtccca tcctttaaac tgaaatatgt catgtgaaat tattttaaaa 1000

 atgtaaaaac aaaactttct gctaacaaaa tacatacagt atctgccagt 1050

 atattctgta aaaccttcta tttgatgtca ttccatttat aatcagaaaa 1100

 aaaacttatt tcttaatcaa aaggcagtac aaaaaaagta ataatgtttt 1150

 ataagattgt agagttaagt aaaagttaag cttttgcaaa gttgtcaaaa 1200

 gttcaaacaa aagtctagtt gggatttttt accaaagcag cataatatgt 1250

 gttatataaa cataataata ctcagatatc caaatgttca gatagcattt 1300

 ttcataatga atgttctctt ttttttggta atagtgtaga agtgatctgg 1350

 ttcttacaat gggagatgaa gaacatttat tattgggtta ctactaaccc 1400

 tgtcccaaga atagtaatat cacctctagt tataagccag caacaggaac 1450

 ttttgtgaag acacattcat ctctacggaa cttcagatta aatataatct 1500

 agattaatga ctgagaataa gatccacatt tgaactcatt cctaagtgaa 1550

 catggacgta cccagttata caaagtactt ctgttggtca cagaaacatg 1600

 accagatttt gcatatctcc aggtagggaa ctaagtagac taccttatca 1650

 ccggctaaga aaacttgcta ctaaactatt aggccatcaa tggcttgaat 1700

 aaaaaccaga gaaggttttt cccaggacgt ctcatgtttg gccctttaga 1750

 attggggtag aaatcagaaa tgagatgagg ggaagaagca aggagtctaa 1800

 ggccctagcg atttgggcat ctgccacatt ggttcatatt cagaaagtgt 1850

 tatctcattg attatattct tgttaagcaa atctccttaa gtaattatta 1900

 ttcaaataag attatactca tacatctata tgtcactgtt ttaaagagat 1950

 atttaatttt taatgtgtgt tacatggtct gtaaatattt gtatttaaaa 2000

 atgccatgca ttaggctttg gaaatttaat gttagttgaa atgtaaaatg 2050

 tgaaaacttt agatcatttg tagtaataaa tatttttaac ttcattcata 2100

 cagttaagtt tatctgacaa taaaagctct gactaaaaaa aaaaaaaaaa 2150

 aaaaaaaaaa aaaa 2164

<210> 3959
<211> 235
<212> PRT
<213> Homo sapien

<400> 3959
 Met Glu Thr Thr Leu Leu Phe Phe Ser Gln Ile Asn Met Cys Glu
   1               5                  10                  15

 Ser Lys Glu Lys Thr Phe Phe Lys Leu Ile His Gly Ser Gly Lys
                  20                  25                  30

 Glu Glu Thr Ser Lys Glu Ala Lys Ile Arg Ala Lys Glu Lys Arg
                  35                  40                  45

 Asn Arg Leu Ser Leu Leu Val Gln Lys Pro Glu Phe His Glu Asp
                  50                  55                  60

 Thr Arg Ser Ser Arg Ser Gly His Leu Ala Lys Glu Thr Arg Val
                  65                  70                  75

 Ser Pro Glu Glu Ala Val Lys Trp Gly Glu Ser Phe Asp Lys Leu
                  80                  85                  90

 Leu Ser His Arg Asp Gly Leu Glu Ala Phe Thr Arg Phe Leu Lys
                  95                 100                 105

 Thr Glu Phe Ser Glu Glu Asn Ile Glu Phe Trp Ile Ala Cys Glu
                 110                 115                 120

 Asp Phe Lys Lys Ser Lys Gly Pro Gln Gln Ile His Leu Lys Ala
                 125                 130                 135

 Lys Ala Ile Tyr Glu Lys Phe Ile Gln Thr Asp Ala Pro Lys Glu
                 140                 145                 150

 Val Asn Leu Asp Phe His Thr Lys Glu Val Ile Thr Asn Ser Ile
                 155                 160                 165

 Thr Gln Pro Thr Leu His Ser Phe Asp Ala Ala Gln Ser Arg Val
                 170                 175                 180

 Tyr Gln Leu Met Glu Gln Asp Ser Tyr Thr Arg Phe Leu Lys Ser
                 185                 190                 195

 Asp Ile Tyr Leu Asp Leu Met Glu Gly Arg Pro Gln Arg Pro Thr
                 200                 205                 210

 Asn Leu Arg Arg Arg Ser Arg Ser Phe Thr Cys Asn Glu Phe Gln
                 215                 220                 225

 Asp Val Gln Ser Asp Val Ala Ile Trp Leu
                 230                 235

<210> 3960
<211> 1138
<212> DNA
<213> Homo sapien

<400> 3960
 ccctttaaag ggtgactcgt cccacttgtg ttctctctcc tggtgcagag 50

 ttgcaagcaa gtttatcaga gtatcgccat gaagttcgtc ccctgcctcc 100

 tgctggtgac cttgtcctgc ctggggactt tgggtcaggc cccgaggcaa 150

 aagcaaggaa gcactgggga ggaattccat ttccagactg gagggagaga 200

 ttcctgcact atgcgtccca gcagcttggg gcaaggtgct ggagaagtct 250

 ggcttcgcgt cgactgccgc aacacagacc agacctactg gtgtgagtac 300

 agggggcagc ccagcatgtg ccaggctttt gctgctgacc ccaaacctta 350

 ctggaatcaa gccctgcagg agctgaggcg ccttcaccat gcgtgccagg 400

 gggccccggt gcttaggcca tccgtgtgca gggaggctgg accccaggcc 450

 catatgcagc aggtgacttc cagcctcaag ggcagcccag agcccaacca 500

 gcagcctgag gctgggacgc catctctgag gcccaaggcc acagtgaaac 550

 tcacagaagc aacacagctg ggaaaggact cgatggaaga gctgggaaaa 600

 gccaaaccca ccacccgacc cacagccaaa cctacccagc ctggacccag 650

 gcccggaggg aatgaggaag caaagaagaa ggcctgggaa cattgttgga 700

 aacccttcca ggccctgtgc gcctttctca tcagcttctt ccgagggtga 750

 caggtgaaag acccctacag atctgacctc tccctgacag acaaccatct 800

 ctttttatat tatgccgctt tcaatccaac gttctcacac tggaagaaga 850

 gagtttctaa tcagatgcaa cggcccaaat tcttgatctg cagcttctct 900

 gaagtttgga aaagaaacct tcctttctgg agtttgcaga gttcagcaat 950

 atgataggga acaggtgctg atgggcccaa gagtgacaag catacacaac 1000

 tacttattat ctgtagaagt tttgctttgt tgatctgagc cttctatgaa 1050

 agtttaaata tgtaacgcat tcatgaattt ccagtgttca gtaaatagca 1100

 gctatgtgtg tgcaaaataa aagaatgatt tcagaaat 1138

<210> 3961
<211> 223
<212> PRT
<213> Homo sapien

<400> 3961
 Met Lys Phe Val Pro Cys Leu Leu Leu Val Thr Leu Ser Cys Leu
   1               5                  10                  15

 Gly Thr Leu Gly Gln Ala Pro Arg Gln Lys Gln Gly Ser Thr Gly
                  20                  25                  30

 Glu Glu Phe His Phe Gln Thr Gly Gly Arg Asp Ser Cys Thr Met
                  35                  40                  45

 Arg Pro Ser Ser Leu Gly Gln Gly Ala Gly Glu Val Trp Leu Arg
                  50                  55                  60

 Val Asp Cys Arg Asn Thr Asp Gln Thr Tyr Trp Cys Glu Tyr Arg
                  65                  70                  75

 Gly Gln Pro Ser Met Cys Gln Ala Phe Ala Ala Asp Pro Lys Pro
                  80                  85                  90

 Tyr Trp Asn Gln Ala Leu Gln Glu Leu Arg Arg Leu His His Ala
                  95                 100                 105

 Cys Gln Gly Ala Pro Val Leu Arg Pro Ser Val Cys Arg Glu Ala
                 110                 115                 120

 Gly Pro Gln Ala His Met Gln Gln Val Thr Ser Ser Leu Lys Gly
                 125                 130                 135

 Ser Pro Glu Pro Asn Gln Gln Pro Glu Ala Gly Thr Pro Ser Leu
                 140                 145                 150

 Arg Pro Lys Ala Thr Val Lys Leu Thr Glu Ala Thr Gln Leu Gly
                 155                 160                 165

 Lys Asp Ser Met Glu Glu Leu Gly Lys Ala Lys Pro Thr Thr Arg
                 170                 175                 180

 Pro Thr Ala Lys Pro Thr Gln Pro Gly Pro Arg Pro Gly Gly Asn
                 185                 190                 195

 Glu Glu Ala Lys Lys Lys Ala Trp Glu His Cys Trp Lys Pro Phe
                 200                 205                 210

 Gln Ala Leu Cys Ala Phe Leu Ile Ser Phe Phe Arg Gly
                 215                 220

<210> 3962
<211> 1003
<212> DNA
<213> Homo sapien

<400> 3962
 gtctacaccc cctcctcaca cgcacttcac ctgggtcggg attctcaggt 50

 catgaacggt cccagccacc tccgggcagg gcgggtgagg acggggacgg 100

 ggcgtgtcca actggctgtg ggctcttgaa acccgagcat ggcacagcac 150

 ggggcgatgg gcgcgtttcg ggccctgtgc ggcctggcgc tgctgtgcgc 200

 gctcagcctg ggtcagcgcc ccaccggggg tcccgggtgc ggccctgggc 250

 gcctcctgct tgggacggga acggacgcgc gctgctgccg ggttcacacg 300

 acgcgctgct gccgcgatta cccgggcgag gagtgctgtt ccgagtggga 350

 ctgcatgtgt gtccagcctg aattccactg cggagaccct tgctgcacga 400

 cctgccggca ccacccttgt cccccaggcc agggggtaca gtcccagggg 450

 aaattcagtt ttggcttcca gtgtatcgac tgtgcctcgg ggaccttctc 500

 cgggggccac gaaggccact gcaaaccttg gacagactgc tgctggaggt 550

 gccgccgtcg accgaagacg ccagaagctg ccagttcccc gaggaagagc 600

 ggggcgagcg atcggcagag gagaaggggc ggctgggaga cctgtgggtg 650

 tgagcctggc cgtcctccgg ggccaccgac cgcagccagc ccctccccag 700

 gagctcccca ggccgcaggg gctctgcgtt ctgctctggg ccgggccctg 750

 ctcccctggc agcagaagtg ggtgcaggaa ggtggcagtg accagcgccc 800

 tggaccatgc agttcggcgg ccgcggctgg gccctgcagg agggagagag 850

 agacacagtc atggccccct tcctcccttg ctggccctga tggggtgggg 900

 tcttaggacg ggaggctgtg tccgtgggtg tgcagtgccc agcacgggac 950

 ccggctgcag gggaccttca ataaacactt gtccagtgaa aaaaaaaaaa 1000

 aaa 1003

<210> 3963
<211> 255
<212> PRT
<213> Homo sapien

<400> 3963
 Met Ala Gln His Gly Ala Met Gly Ala Phe Arg Ala Leu Cys Gly
   1               5                  10                  15

 Leu Ala Leu Leu Cys Ala Leu Ser Leu Gly Gln Arg Pro Thr Gly
                  20                  25                  30

 Gly Pro Gly Cys Gly Pro Gly Arg Leu Leu Leu Gly Thr Gly Thr
                  35                  40                  45

 Asp Ala Arg Cys Cys Arg Val His Thr Thr Arg Cys Cys Arg Asp
                  50                  55                  60

 Tyr Pro Gly Glu Glu Cys Cys Ser Glu Trp Asp Cys Met Cys Val
                  65                  70                  75

 Gln Pro Glu Phe His Cys Gly Asp Pro Cys Cys Thr Thr Cys Arg
                  80                  85                  90

 His His Pro Cys Pro Pro Gly Gln Gly Val Gln Ser Gln Gly Lys
                  95                 100                 105

 Phe Ser Phe Gly Phe Gln Cys Ile Asp Cys Ala Ser Gly Thr Phe
                 110                 115                 120

 Ser Gly Gly His Glu Gly His Cys Lys Pro Trp Thr Asp Cys Cys
                 125                 130                 135

 Trp Arg Cys Arg Arg Arg Pro Lys Thr Pro Glu Ala Ala Ser Ser
                 140                 145                 150

 Pro Arg Lys Ser Gly Ala Ser Asp Arg Gln Arg Arg Arg Gly Gly
                 155                 160                 165

 Trp Glu Thr Cys Gly Cys Glu Pro Gly Arg Pro Pro Gly Pro Pro
                 170                 175                 180

 Thr Ala Ala Ser Pro Ser Pro Gly Ala Pro Gln Ala Ala Gly Ala
                 185                 190                 195

 Leu Arg Ser Ala Leu Gly Arg Ala Leu Leu Pro Trp Gln Gln Lys
                 200                 205                 210

 Trp Val Gln Glu Gly Gly Ser Asp Gln Arg Pro Gly Pro Cys Ser
                 215                 220                 225

 Ser Ala Ala Ala Ala Gly Pro Cys Arg Arg Glu Arg Glu Thr Gln
                 230                 235                 240

 Ser Trp Pro Pro Ser Ser Leu Ala Gly Pro Asp Gly Val Gly Ser
                 245                 250                 255

<210> 3964
<211> 1419
<212> DNA
<213> Homo sapien

<400> 3964
 gcagtttcta tagtagtttt aaattattat taaatcacct gaaaaaaatt 50

 ccaaaagaga accacacact accatatcca aacaactttt gcatttccca 100

 taattgtagt taatgtcagc ccagtaggcc agaccaaccc ccagttcaat 150

 actttccttc cccaaaagct ctatactttg aaggaaaaca gatacagtat 200

 caaattatga cactttcctt gcccaaatta atgcactggt acacccagtg 250

 gctcatattt aacttccccc agcttcccaa ttcaaactgg ggggaaaaaa 300

 actaaatcat tgggagttac ttgccaactt ggaagttgat atttctttac 350

 tttttccatt ctaagacttt aagttctctg gcatgagttt atctgcaatc 400

 ataaactaaa caattaccta aacccacccc accaatccca accgtaacag 450

 gccactgcca actaattgcc aatatttgcc cctccccttt aataaaactt 500

 ttaagaagtc acattattgg aaaacttaac ttcaacattt ggcctactca 550

 agctcttctg aagttctcct gagatgactg aatatgaacc aaagctgcac 600

 tgtgctgtac ttttcagctt caactgggaa tactcttcca aggataaaag 650

 cagctccagt ccctgaaggt gttcgtgcca acagcacagc ggtacactcc 700

 ttctctaacc cagtttgtca atagtactat agcatctgtg gaaaatctta 750

 gaaaaaaaca ttttctcccc caccctctct cttccctgtt aagaccatcc 800

 caaaatgctt caagtaaaaa ataacaagtt taaggggtta agcactttta 850

 aagtctgatt aagggggtgg ggggaaaaaa gagtaactac cagccatttc 900

 tccaatggac atctcttcca cagacctcaa cgtgagaact gctctagttt 950

 ctataaactg taaacctgtg gtggtctgat tatcctgata ttggattttc 1000

 ttgttttctg ttacaccttg agtcatttgc ctttaggatt ctagacagac 1050

 ctaagggaaa aagaactgaa aacatatttt gcccccaccc ccacaaaaaa 1100

 aaatactgaa aactcccccc cgcctcagtt acacatccaa actctacatt 1150

 tacaaaacga attcagggtg aggaagtaaa aacaggtcat ctattcacaa 1200

 aactgaaata cttcattacc ccaactaaac atacaaactg cttacagatt 1250

 tgctgaaatt gtctcaattt ggctatcaaa ttcatttggt tttcctcaaa 1300

 ttcgtgtaaa aaaaaaaaac ccacaaactt gccatctact atttctccag 1350

 gacttggcag tctgccctca aaagcttcag acaagattca tgagtataag 1400

 cctgaaaaaa aaaaaaaaa 1419

<210> 3965
<211> 5227
<212> DNA
<213> Homo sapien

<400> 3965
 gctgttggct gggctcggga gggaacgctc caggtaaagc gctgggggag 50

 gaagcgacgc cgaggagcta cggtttcctc cagaggtctc cgcccctctg 100

 cccctatatt cccagagctc gagtctgatc cgggccttgc cgggcaccct 150

 ggaaaggcgg gggtgatagt acagatggag acgcaactgc agagcatttt 200

 cgaagaggtg gtgaaaacgg aagttataga agaggctttt cctggcatgt 250

 ttatggatac tcctgaagat gagaaaacaa aactaattag ctgtttgggg 300

 gccttcagac agttttgggg tggtctttct caggagtctc atgaacagtg 350

 tatccagtgg attgttaagt ttattcatgg tcagcatagt cctaaaagaa 400

 tttcttttct ttatgactgc ttagcaatgg cagttgagac tggtctcctt 450

 ccacccaggc tggtttgtga atccctgata aactctgaca ctcttgagtg 500

 ggaaagaaca cagctttggg ccttaacatt taaactggtt cggaaaataa 550

 ttgggggagt ggattacaag ggtgttcgag atctcttaaa agtgattttg 600

 gagaagattt tgacaattcc taatacagtg agctctgctg ttgtacagca 650

 gcttctggca gcaagagagg ttatagcata tatcttggaa agaaatgcct 700

 gcttattacc agcctatttt gcagtcactg agatcaggaa actgtatcct 750

 gaaggcaaac ttccacactg gttacttgga aacctagtat cagactttgt 800

 ggataccttc aggcccacag caaggataaa ctccatttgt ggtcgctgta 850

 gtcttctgcc agttgtaaat aattcgggtg ccatttgtaa ttcatggaaa 900

 ctggatcctg ctactcttcg ttttcctttg aaaggccttt tgccatatga 950

 taaggatctg tttgaaccac agactgcttt gttgagatat gtattggagc 1000

 agccttattc cagggatatg gtctgcaata tgctaggttt aaataagcag 1050

 cacaagcagc gctgccctgt gctggaggac cagttggtgg atctggttgt 1100

 ttatgccatg gagcgatctg agaccgagga gaagtttgac gatgggggaa 1150

 caagccaact cctgtggcag catctctcaa gtcagctcat tttctttgtg 1200

 cttttccagt ttgcaagttt tccacatatg gtgctttctc ttcatcagaa 1250

 gttagcaggg cgaggactga ttaaaggcag agatcatctt atgtgggttc 1300

 tcctgcaatt catttctgga agtattcaga aaaatgcact agctgatttt 1350

 ctccctgtga tgaagctctt cgacttgcta tacccagaaa aagaatatat 1400

 cccagttcct gatattaaca aaccccagtc aacccatgcc tttgcaatga 1450

 cctgtatttg gattcatctc aatagaaaag ctcaaaatga caactccaag 1500

 ctacagattc caatacctca ttccctaaga cttcaccatg agttcctgca 1550

 gcagagtcta agaaataaaa gtttacagat gaatgactat aagattgctc 1600

 tattgtgtaa tgcatactct acaaattcag aatgttttac attacccatg 1650

 ggagctctgg tagaaactat ttatggaaat ggaattatga ggatacctct 1700

 ccctggaaca aactgtatgg cttcaggatc tattaccccc ttacctatga 1750

 acctcctgga ttcactgaca gttcatgcca aaatgagcct tattcacagc 1800

 attgcaacca gggtgataaa acttgctcat gcaaagtcca gtgtggcctt 1850

 ggctccagcc ctagtggaaa cttacagtcg tttattggtc tatatggaaa 1900

 tagagtcttt gggcatcaaa ggatttatca gtcagctttt gccaactgtt 1950

 ttcaaatcac atgcatgggg gatcttacac acactccttg agatgtttag 2000

 ctaccggatg catcatattc agcctcatta cagagttcag ctcctgagtc 2050

 atcttcatac tttggctgca gttgcacaaa caaaccagaa ccagctccat 2100

 ctttgtgtcg agagcactgc tctcaggctt ataacagcat taggtagctc 2150

 agaggtacaa ccgcagttta cacgcttcct tagtgatccc aaaacagtgc 2200

 tctcagcaga atctgaagaa ctgaaccgag ccttgatatt gaccttggct 2250

 agagcaactc atgtaacaga tttttttaca ggctctgatt caattcaggg 2300

 aacttggtgt aaagacatac ttcagaccat catgagtttc actcctcata 2350

 attgggcttc acacaccctg agctgttttc caggcccact acaggcattc 2400

 ttcaaacaaa ataatgtgcc tcaggaaagc cgttttaatc tgaaaaaaaa 2450

 tgtggaggag gagtatagga agtggaagtc aatgagcaac gaaaacgaca 2500

 ttattaccca cttctctatg cagggctccc ctcctctctt tctttgtctt 2550

 ctctggaaaa tgctcttgga aacagatcat attaatcaga ttggctatag 2600

 agtattagag agaattggag ccagggcctt ggtagcccat gtgaggacat 2650

 ttgcagattt cctggtatat gagttttcta catcagcagg gggtcagcaa 2700

 ctcaataaat gcattgaaat tcttaatgac atggtatgga agtataacat 2750

 tgttacactg gacagattaa ttctctgcct ggccatgcgt agtcacgaag 2800

 gaaatgaagc ccaggtttgt tatttcataa ttcagttgct gttactcaaa 2850

 ccaaacgatt ttagaaatcg agtaagtgac tttgtgaagg aaaattcccc 2900

 agagcactgg ttacagaatg actggcacac caagcacatg aattatcaca 2950

 agaaatatcc agagaagttg tattttgagg gcctcgcgga acaggtggat 3000

 cctcctgtac agatccagtc tccctatctg cccatctatt ttgggaatgt 3050

 gtgtcttcga ttccttccag tatttgatat agtaatccac agatttttag 3100

 agttgcttcc ggtatccaaa tcactggaga ctctactgga tcatctagga 3150

 ggcttatata aatttcatga tcgtccagtg acttatctgt ataacactct 3200

 gcactattat gaaatgcacc tgagagaccg cgcatttctc aaacgaaaac 3250

 tcgtccatgc gatcattggc tctctgaagg ataatcgacc gcagggctgg 3300

 tgtctaagtg acacttacct gaaatgcgct atgaatgcac gagaggaaaa 3350

 tccttgggtt ccagatgaca cctactattg cagattgatt ggcagactag 3400

 tcgatacgat ggctggcaaa tctcctggtc cctttccaaa ctgtgactgg 3450

 agattcaatg agtttcccaa cccagctgcc catgctctcc atgttacttg 3500

 tgtggagctc atggccttgg cagtttcagg caaagaagtt gggaatgccc 3550

 ttctaaatgt tgtcctaaaa agtcagcctt tagtgccaag agagaacatt 3600

 acagcatgga tgaatgcaat tggtttgatc atcactgccc taccagagcc 3650

 atattggatt gttcttcatg atcgaattgt gagtgtcatc agcagcccca 3700

 gcttgacgtc tgaaacagag tgggttggct atccattccg cctctttgat 3750

 ttcactgcct gtcatcagtc ctactctgag atgagttgta gctatacgtt 3800

 agctcttgca catgctgtgt ggcaccattc tagcatcgga caactttctc 3850

 tcattccaaa gtttcttact gaagtacttc ttcctatagt gaagaccgaa 3900

 ttccagttgc tttatgtata ccatcttgtt ggaccatttt tacaaagatt 3950

 tcagcaagag agaactcgtt gtatgataga gattggtgtg gcgttttatg 4000

 acatgctgct gaatgttgac cagtgtagca cccatttaaa ttacatggat 4050

 cccatctgtg acttcctcta tcacatgaag tatatgttta ctggtgacag 4100

 cgtgaaagag caagtagaga agattatctg taacttaaaa ccagctttaa 4150

 aacttcgtct tcgattcatc acacacatta gcaagatgga gccagctgca 4200

 gtgcctccac aagccatgaa cagtgggtct ccagcacctc agtctaatca 4250

 ggtgcccgtg tctttaccag taactcagtg aagccagact gtactgtgga 4300

 gaaagtagaa atatatccgt ctttgagagt ggactcaaac cttttaaatc 4350

 tgaatgcgat cacactgtag tgatatagta gaagcagtga tgatattcag 4400

 attgttttat tttgattcaa atgatgaatc tgttgacacc ttataactcc 4450

 catctcccta tctatatttt tgtctctaag agatcaagta agatacatgt 4500

 tgttcatatt cataacaact tattagagct atgtaggaac atagaggtat 4550

 ctgtgatcaa atgacttgtc attggcactt tcagtctttc ctattctagc 4600

 cgttgttttt gtttgtattt tttattatta atgacatatt tagtcttcag 4650

 atatattatt ttaaaggcac cacacatgta aaacagttat tacaaatatt 4700

 ttatacataa atctcttggt agattttcag aataatagag atttatatca 4750

 agaaaaggaa tctagatttt gttgcattgt aggagcaaac aaggcttcat 4800

 attcttttta aaatgacttg aaattttatt ataaatttcc atagtttcta 4850

 tcaaggtcaa ctggcagttt tattaccttt gctatggact tgaacttact 4900

 gtataaaatt agttggaagc catgtaagaa aataacatct gaaaattctt 4950

 gaacttaaaa tcatgcttaa atggttgatt ctccaatttc tttttttaaa 5000

 aataagttaa ttgcttttgc aggttgacac tctcacctga cagatgatgt 5050

 aattcttcaa tttttataat cttaaaattt ttaaatttta tatttgtaaa 5100

 tacagtacac attttatttc ttggattttg agagacattg ttaattttgg 5150

 gggaattggc attgcgaaag acttgaaaac taatgagtaa agtctgctga 5200

 atgaataaac cgtgtgattg tttcccg 5227

<210> 3966
<211> 1368
<212> PRT
<213> Homo sapien

<400> 3966
 Met Glu Thr Gln Leu Gln Ser Ile Phe Glu Glu Val Val Lys Thr
   1               5                  10                  15

 Glu Val Ile Glu Glu Ala Phe Pro Gly Met Phe Met Asp Thr Pro
                  20                  25                  30

 Glu Asp Glu Lys Thr Lys Leu Ile Ser Cys Leu Gly Ala Phe Arg
                  35                  40                  45

 Gln Phe Trp Gly Gly Leu Ser Gln Glu Ser His Glu Gln Cys Ile
                  50                  55                  60

 Gln Trp Ile Val Lys Phe Ile His Gly Gln His Ser Pro Lys Arg
                  65                  70                  75

 Ile Ser Phe Leu Tyr Asp Cys Leu Ala Met Ala Val Glu Thr Gly
                  80                  85                  90

 Leu Leu Pro Pro Arg Leu Val Cys Glu Ser Leu Ile Asn Ser Asp
                  95                 100                 105

 Thr Leu Glu Trp Glu Arg Thr Gln Leu Trp Ala Leu Thr Phe Lys
                 110                 115                 120

 Leu Val Arg Lys Ile Ile Gly Gly Val Asp Tyr Lys Gly Val Arg
                 125                 130                 135

 Asp Leu Leu Lys Val Ile Leu Glu Lys Ile Leu Thr Ile Pro Asn
                 140                 145                 150

 Thr Val Ser Ser Ala Val Val Gln Gln Leu Leu Ala Ala Arg Glu
                 155                 160                 165

 Val Ile Ala Tyr Ile Leu Glu Arg Asn Ala Cys Leu Leu Pro Ala
                 170                 175                 180

 Tyr Phe Ala Val Thr Glu Ile Arg Lys Leu Tyr Pro Glu Gly Lys
                 185                 190                 195

 Leu Pro His Trp Leu Leu Gly Asn Leu Val Ser Asp Phe Val Asp
                 200                 205                 210

 Thr Phe Arg Pro Thr Ala Arg Ile Asn Ser Ile Cys Gly Arg Cys
                 215                 220                 225

 Ser Leu Leu Pro Val Val Asn Asn Ser Gly Ala Ile Cys Asn Ser
                 230                 235                 240

 Trp Lys Leu Asp Pro Ala Thr Leu Arg Phe Pro Leu Lys Gly Leu
                 245                 250                 255

 Leu Pro Tyr Asp Lys Asp Leu Phe Glu Pro Gln Thr Ala Leu Leu
                 260                 265                 270

 Arg Tyr Val Leu Glu Gln Pro Tyr Ser Arg Asp Met Val Cys Asn
                 275                 280                 285

 Met Leu Gly Leu Asn Lys Gln His Lys Gln Arg Cys Pro Val Leu
                 290                 295                 300

 Glu Asp Gln Leu Val Asp Leu Val Val Tyr Ala Met Glu Arg Ser
                 305                 310                 315

 Glu Thr Glu Glu Lys Phe Asp Asp Gly Gly Thr Ser Gln Leu Leu
                 320                 325                 330

 Trp Gln His Leu Ser Ser Gln Leu Ile Phe Phe Val Leu Phe Gln
                 335                 340                 345

 Phe Ala Ser Phe Pro His Met Val Leu Ser Leu His Gln Lys Leu
                 350                 355                 360

 Ala Gly Arg Gly Leu Ile Lys Gly Arg Asp His Leu Met Trp Val
                 365                 370                 375

 Leu Leu Gln Phe Ile Ser Gly Ser Ile Gln Lys Asn Ala Leu Ala
                 380                 385                 390

 Asp Phe Leu Pro Val Met Lys Leu Phe Asp Leu Leu Tyr Pro Glu
                 395                 400                 405

 Lys Glu Tyr Ile Pro Val Pro Asp Ile Asn Lys Pro Gln Ser Thr
                 410                 415                 420

 His Ala Phe Ala Met Thr Cys Ile Trp Ile His Leu Asn Arg Lys
                 425                 430                 435

 Ala Gln Asn Asp Asn Ser Lys Leu Gln Ile Pro Ile Pro His Ser
                 440                 445                 450

 Leu Arg Leu His His Glu Phe Leu Gln Gln Ser Leu Arg Asn Lys
                 455                 460                 465

 Ser Leu Gln Met Asn Asp Tyr Lys Ile Ala Leu Leu Cys Asn Ala
                 470                 475                 480

 Tyr Ser Thr Asn Ser Glu Cys Phe Thr Leu Pro Met Gly Ala Leu
                 485                 490                 495

 Val Glu Thr Ile Tyr Gly Asn Gly Ile Met Arg Ile Pro Leu Pro
                 500                 505                 510

 Gly Thr Asn Cys Met Ala Ser Gly Ser Ile Thr Pro Leu Pro Met
                 515                 520                 525

 Asn Leu Leu Asp Ser Leu Thr Val His Ala Lys Met Ser Leu Ile
                 530                 535                 540

 His Ser Ile Ala Thr Arg Val Ile Lys Leu Ala His Ala Lys Ser
                 545                 550                 555

 Ser Val Ala Leu Ala Pro Ala Leu Val Glu Thr Tyr Ser Arg Leu
                 560                 565                 570

 Leu Val Tyr Met Glu Ile Glu Ser Leu Gly Ile Lys Gly Phe Ile
                 575                 580                 585

 Ser Gln Leu Leu Pro Thr Val Phe Lys Ser His Ala Trp Gly Ile
                 590                 595                 600

 Leu His Thr Leu Leu Glu Met Phe Ser Tyr Arg Met His His Ile
                 605                 610                 615

 Gln Pro His Tyr Arg Val Gln Leu Leu Ser His Leu His Thr Leu
                 620                 625                 630

 Ala Ala Val Ala Gln Thr Asn Gln Asn Gln Leu His Leu Cys Val
                 635                 640                 645

 Glu Ser Thr Ala Leu Arg Leu Ile Thr Ala Leu Gly Ser Ser Glu
                 650                 655                 660

 Val Gln Pro Gln Phe Thr Arg Phe Leu Ser Asp Pro Lys Thr Val
                 665                 670                 675

 Leu Ser Ala Glu Ser Glu Glu Leu Asn Arg Ala Leu Ile Leu Thr
                 680                 685                 690

 Leu Ala Arg Ala Thr His Val Thr Asp Phe Phe Thr Gly Ser Asp
                 695                 700                 705

 Ser Ile Gln Gly Thr Trp Cys Lys Asp Ile Leu Gln Thr Ile Met
                 710                 715                 720

 Ser Phe Thr Pro His Asn Trp Ala Ser His Thr Leu Ser Cys Phe
                 725                 730                 735

 Pro Gly Pro Leu Gln Ala Phe Phe Lys Gln Asn Asn Val Pro Gln
                 740                 745                 750

 Glu Ser Arg Phe Asn Leu Lys Lys Asn Val Glu Glu Glu Tyr Arg
                 755                 760                 765

 Lys Trp Lys Ser Met Ser Asn Glu Asn Asp Ile Ile Thr His Phe
                 770                 775                 780

 Ser Met Gln Gly Ser Pro Pro Leu Phe Leu Cys Leu Leu Trp Lys
                 785                 790                 795

 Met Leu Leu Glu Thr Asp His Ile Asn Gln Ile Gly Tyr Arg Val
                 800                 805                 810

 Leu Glu Arg Ile Gly Ala Arg Ala Leu Val Ala His Val Arg Thr
                 815                 820                 825

 Phe Ala Asp Phe Leu Val Tyr Glu Phe Ser Thr Ser Ala Gly Gly
                 830                 835                 840

 Gln Gln Leu Asn Lys Cys Ile Glu Ile Leu Asn Asp Met Val Trp
                 845                 850                 855

 Lys Tyr Asn Ile Val Thr Leu Asp Arg Leu Ile Leu Cys Leu Ala
                 860                 865                 870

 Met Arg Ser His Glu Gly Asn Glu Ala Gln Val Cys Tyr Phe Ile
                 875                 880                 885

 Ile Gln Leu Leu Leu Leu Lys Pro Asn Asp Phe Arg Asn Arg Val
                 890                 895                 900

 Ser Asp Phe Val Lys Glu Asn Ser Pro Glu His Trp Leu Gln Asn
                 905                 910                 915

 Asp Trp His Thr Lys His Met Asn Tyr His Lys Lys Tyr Pro Glu
                 920                 925                 930

 Lys Leu Tyr Phe Glu Gly Leu Ala Glu Gln Val Asp Pro Pro Val
                 935                 940                 945

 Gln Ile Gln Ser Pro Tyr Leu Pro Ile Tyr Phe Gly Asn Val Cys
                 950                 955                 960

 Leu Arg Phe Leu Pro Val Phe Asp Ile Val Ile His Arg Phe Leu
                 965                 970                 975

 Glu Leu Leu Pro Val Ser Lys Ser Leu Glu Thr Leu Leu Asp His
                 980                 985                 990

 Leu Gly Gly Leu Tyr Lys Phe His Asp Arg Pro Val Thr Tyr Leu
                 995                1000                1005

 Tyr Asn Thr Leu His Tyr Tyr Glu Met His Leu Arg Asp Arg Ala
                1010                1015                1020

 Phe Leu Lys Arg Lys Leu Val His Ala Ile Ile Gly Ser Leu Lys
                1025                1030                1035

 Asp Asn Arg Pro Gln Gly Trp Cys Leu Ser Asp Thr Tyr Leu Lys
                1040                1045                1050

 Cys Ala Met Asn Ala Arg Glu Glu Asn Pro Trp Val Pro Asp Asp
                1055                1060                1065

 Thr Tyr Tyr Cys Arg Leu Ile Gly Arg Leu Val Asp Thr Met Ala
                1070                1075                1080

 Gly Lys Ser Pro Gly Pro Phe Pro Asn Cys Asp Trp Arg Phe Asn
                1085                1090                1095

 Glu Phe Pro Asn Pro Ala Ala His Ala Leu His Val Thr Cys Val
                1100                1105                1110

 Glu Leu Met Ala Leu Ala Val Ser Gly Lys Glu Val Gly Asn Ala
                1115                1120                1125

 Leu Leu Asn Val Val Leu Lys Ser Gln Pro Leu Val Pro Arg Glu
                1130                1135                1140

 Asn Ile Thr Ala Trp Met Asn Ala Ile Gly Leu Ile Ile Thr Ala
                1145                1150                1155

 Leu Pro Glu Pro Tyr Trp Ile Val Leu His Asp Arg Ile Val Ser
                1160                1165                1170

 Val Ile Ser Ser Pro Ser Leu Thr Ser Glu Thr Glu Trp Val Gly
                1175                1180                1185

 Tyr Pro Phe Arg Leu Phe Asp Phe Thr Ala Cys His Gln Ser Tyr
                1190                1195                1200

 Ser Glu Met Ser Cys Ser Tyr Thr Leu Ala Leu Ala His Ala Val
                1205                1210                1215

 Trp His His Ser Ser Ile Gly Gln Leu Ser Leu Ile Pro Lys Phe
                1220                1225                1230

 Leu Thr Glu Val Leu Leu Pro Ile Val Lys Thr Glu Phe Gln Leu
                1235                1240                1245

 Leu Tyr Val Tyr His Leu Val Gly Pro Phe Leu Gln Arg Phe Gln
                1250                1255                1260

 Gln Glu Arg Thr Arg Cys Met Ile Glu Ile Gly Val Ala Phe Tyr
                1265                1270                1275

 Asp Met Leu Leu Asn Val Asp Gln Cys Ser Thr His Leu Asn Tyr
                1280                1285                1290

 Met Asp Pro Ile Cys Asp Phe Leu Tyr His Met Lys Tyr Met Phe
                1295                1300                1305

 Thr Gly Asp Ser Val Lys Glu Gln Val Glu Lys Ile Ile Cys Asn
                1310                1315                1320

 Leu Lys Pro Ala Leu Lys Leu Arg Leu Arg Phe Ile Thr His Ile
                1325                1330                1335

 Ser Lys Met Glu Pro Ala Ala Val Pro Pro Gln Ala Met Asn Ser
                1340                1345                1350

 Gly Ser Pro Ala Pro Gln Ser Asn Gln Val Pro Val Ser Leu Pro
                1355                1360                1365

 Val Thr Gln


<210> 3967
<211> 2468
<212> DNA
<213> Homo sapien

<400> 3967
 accgggcacc ggacggctcg ggtactttcg ttcttaatta ggtcatgccc 50

 gtgtgagcca ggaaagggct gtgtttatgg gaagccagta acactgtggc 100

 ctactatctc ttccgtggtg ccatctacat ttttgggact cgggaattat 150

 gaggtagagg tggaggcgga gccggatgtc agaggtcctg aaatagtcac 200

 catgggggaa aatgatccgc ctgctgttga agcccccttc tcattccgat 250

 cgctttttgg ccttgatgat ttgaaaataa gtcctgttgc accagatgca 300

 gatgctgttg ctgcacagat cctgtcactg ctgccattga agttttttcc 350

 aatcatcgtc attgggatca ttgcattgat attagcactg gccattggtc 400

 tgggcatcca cttcgactgc tcagggaagt acagatgtcg ctcatccttt 450

 aagtgtatcg agctgatagc tcgatgtgac ggagtctcgg attgcaaaga 500

 cggggaggac gagtaccgct gtgtccgggt gggtggtcag aatgccgtgc 550

 tccaggtgtt cacagctgct tcgtggaaga ccatgtgctc cgatgactgg 600

 aagggtcact acgcaaatgt tgcctgtgcc caactgggtt tcccaagcta 650

 tgtgagttca gataacctca gagtgagctc gctggagggg cagttccggg 700

 aggagtttgt gtccatcgat cacctcttgc cagatgacaa ggtgactgca 750

 ttacaccact cagtatatgt gagggaggga tgtgcctctg gccacgtggt 800

 taccttgcag tgcacagcct gtggtcatag aaggggctac agctcacgca 850

 tcgtgggtgg aaacatgtcc ttgctctcgc agtggccctg gcaggccagc 900

 cttcagttcc agggctacca cctgtgcggg ggctctgtca tcacgcccct 950

 gtggatcatc actgctgcac actgtgttta tgacttgtac ctccccaagt 1000

 catggaccat ccaggtgggt ctagtttccc tgttggacaa tccagcccca 1050

 tcccacttgg tggagaagat tgtctaccac agcaagtaca agccaaagag 1100

 gctgggcaat gacatcgccc ttatgaagct ggccgggcca ctcacgttca 1150

 atgaaatgat ccagcctgtg tgcctgccca actctgaaga gaacttcccc 1200

 gatggaaaag tgtgctggac gtcaggatgg ggggccacag aggatggagc 1250

 aggtgacgcc tcccctgtcc tgaaccacgc ggccgtccct ttgatttcca 1300

 acaagatctg caaccacagg gacgtgtacg gtggcatcat ctccccctcc 1350

 atgctctgcg cgggctacct gacgggtggc gtggacagct gccaggggga 1400

 cagcgggggg cccctggtgt gtcaagagag gaggctgtgg aagttagtgg 1450

 gagcgaccag ctttggcatc ggctgcgcag aggtgaacaa gcctggggtg 1500

 tacacccgtg tcacctcctt cctggactgg atccacgagc agatggagag 1550

 agacctaaaa acctgaagag gaaggggaca agtagccacc tgagttcctg 1600

 aggtgatgaa gacagcccga tcctcccctg gactcccgtg taggaacctg 1650

 cacacgagca gacacccttg gagctctgag ttccggcacc agtagcaggc 1700

 ccgaaagagg cacccttcca tctgattcca gcacaacctt caagctgctt 1750

 tttgtttttt gtttttttga ggtggagtct cgctctgttg cccaggctgg 1800

 agtgcagtgg cgaaatccct gctcactgca gcctccgctt ccctggttca 1850

 agcgattctc ttgcctcagc ttccccagta gctgggacca caggtgcccg 1900

 ccaccacacc caactaattt ttgtattttt agtagagaca gggtttcacc 1950

 atgttggcca ggctgctctc aaacccctga cctcaaatga tgtgcctgct 2000

 tcagcctccc acagtgctgg gattacaggc atgggccacc acgcctagcc 2050

 tcacgctcct ttctgatctt cactaagaac aaaagaagca gcaacttgca 2100

 agggcggcct ttcccactgg tccatctggt tttctctcca ggggtcttgc 2150

 aaaattcctg acgagataag cagttatgtg acctcacgtg caaagccacc 2200

 aacagccact cagaaaagac gcaccagccc agaagtgcag aactgcagtc 2250

 actgcacgtt ttcatctcta gggaccagaa ccaaacccac cctttctact 2300

 tccaagactt attttcacat gtggggaggt taatctagga atgactcgtt 2350

 taaggcctat tttcatgatt tctttgtagc atttggtgct tgacgtatta 2400

 ttgtcctttg attccaaata atatgtttcc ttccctcaaa aaaaaaaaaa 2450

 aaaaaaaaaa aaaaaaaa 2468

<210> 3968
<211> 454
<212> PRT
<213> Homo sapien

<400> 3968
 Met Gly Glu Asn Asp Pro Pro Ala Val Glu Ala Pro Phe Ser Phe
   1               5                  10                  15

 Arg Ser Leu Phe Gly Leu Asp Asp Leu Lys Ile Ser Pro Val Ala
                  20                  25                  30

 Pro Asp Ala Asp Ala Val Ala Ala Gln Ile Leu Ser Leu Leu Pro
                  35                  40                  45

 Leu Lys Phe Phe Pro Ile Ile Val Ile Gly Ile Ile Ala Leu Ile
                  50                  55                  60

 Leu Ala Leu Ala Ile Gly Leu Gly Ile His Phe Asp Cys Ser Gly
                  65                  70                  75

 Lys Tyr Arg Cys Arg Ser Ser Phe Lys Cys Ile Glu Leu Ile Ala
                  80                  85                  90

 Arg Cys Asp Gly Val Ser Asp Cys Lys Asp Gly Glu Asp Glu Tyr
                  95                 100                 105

 Arg Cys Val Arg Val Gly Gly Gln Asn Ala Val Leu Gln Val Phe
                 110                 115                 120

 Thr Ala Ala Ser Trp Lys Thr Met Cys Ser Asp Asp Trp Lys Gly
                 125                 130                 135

 His Tyr Ala Asn Val Ala Cys Ala Gln Leu Gly Phe Pro Ser Tyr
                 140                 145                 150

 Val Ser Ser Asp Asn Leu Arg Val Ser Ser Leu Glu Gly Gln Phe
                 155                 160                 165

 Arg Glu Glu Phe Val Ser Ile Asp His Leu Leu Pro Asp Asp Lys
                 170                 175                 180

 Val Thr Ala Leu His His Ser Val Tyr Val Arg Glu Gly Cys Ala
                 185                 190                 195

 Ser Gly His Val Val Thr Leu Gln Cys Thr Ala Cys Gly His Arg
                 200                 205                 210

 Arg Gly Tyr Ser Ser Arg Ile Val Gly Gly Asn Met Ser Leu Leu
                 215                 220                 225

 Ser Gln Trp Pro Trp Gln Ala Ser Leu Gln Phe Gln Gly Tyr His
                 230                 235                 240

 Leu Cys Gly Gly Ser Val Ile Thr Pro Leu Trp Ile Ile Thr Ala
                 245                 250                 255

 Ala His Cys Val Tyr Asp Leu Tyr Leu Pro Lys Ser Trp Thr Ile
                 260                 265                 270

 Gln Val Gly Leu Val Ser Leu Leu Asp Asn Pro Ala Pro Ser His
                 275                 280                 285

 Leu Val Glu Lys Ile Val Tyr His Ser Lys Tyr Lys Pro Lys Arg
                 290                 295                 300

 Leu Gly Asn Asp Ile Ala Leu Met Lys Leu Ala Gly Pro Leu Thr
                 305                 310                 315

 Phe Asn Glu Met Ile Gln Pro Val Cys Leu Pro Asn Ser Glu Glu
                 320                 325                 330

 Asn Phe Pro Asp Gly Lys Val Cys Trp Thr Ser Gly Trp Gly Ala
                 335                 340                 345

 Thr Glu Asp Gly Ala Gly Asp Ala Ser Pro Val Leu Asn His Ala
                 350                 355                 360

 Ala Val Pro Leu Ile Ser Asn Lys Ile Cys Asn His Arg Asp Val
                 365                 370                 375

 Tyr Gly Gly Ile Ile Ser Pro Ser Met Leu Cys Ala Gly Tyr Leu
                 380                 385                 390

 Thr Gly Gly Val Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro Leu
                 395                 400                 405

 Val Cys Gln Glu Arg Arg Leu Trp Lys Leu Val Gly Ala Thr Ser
                 410                 415                 420

 Phe Gly Ile Gly Cys Ala Glu Val Asn Lys Pro Gly Val Tyr Thr
                 425                 430                 435

 Arg Val Thr Ser Phe Leu Asp Trp Ile His Glu Gln Met Glu Arg
                 440                 445                 450

 Asp Leu Lys Thr


<210> 3969
<211> 1359
<212> DNA
<213> Homo sapien

<400> 3969
 accgggcacc ggacggctcg ggtactttcg ttcttaatta ggtcatgccc 50

 gtgtgagcca ggaaagggct gtgtttatgg gaagccagta acactgtggc 100

 ctactatctc ttccgtggtg ccatctacat ttttgggact cgggaattat 150

 gaggtagagg tggaggcgga gccggatgtc agaggtcctg aaatagtcac 200

 catgggggaa aatgatccgc ctgctgttga agcccccttc tcattccgat 250

 cgctttttgg ccttgatgat ttgaaaataa gtcctgttgc accagatgca 300

 gatgctgttg ctgcacagat cctgtcactg ctgccattga agttttttcc 350

 aatcatcgtc attgggatca ttgcattgat attagcactg gccattggtc 400

 tgggcatcca cttcgactgc tcagggaagt acagatgtcg ctcatccttt 450

 aagtgtatcg agctgatagc tcgatgtgac ggagtctcgg attgcaaaga 500

 cggggaggac gagtaccgct gtgtccgggt gggtggtcag aatgccgtgc 550

 tccaggtgtt cacagctgct tcgtggaaga ccatgtgctc cgatgactgg 600

 aagggtcact acgcaaatgt tgcctgtgcc caactgggtt tcccaagcta 650

 tgtgagttca gataacctca gagtgagctc gctggagggg cagttccggg 700

 aggagtttgt gtccatcgat cacctcttgc cagatgacaa ggtgactgca 750

 ttacaccact cagtatatgt gagggaggga tgtgcctctg gccacgtggt 800

 taccttgcag tgcacagcct gtggtcatag aaggggctac agctcacgca 850

 tcgtgggtgg aaacatgtcc ttgctctcgc agtggccctg gcaggccagc 900

 cttcagttcc agggctacca cctgtgcggg ggctctgtca tcacgcccct 950

 gtggatcatc actgctgcac actgtgttta tgacttgtac ctccccaagt 1000

 catggaccat ccaggtgggt ctagtttccc tgttggacaa tccagcccca 1050

 tcccacttgg tggagaagat tgtctaccac agcaagtaca agccaaagag 1100

 gctgggcaat gacatcgccc ttatgaagct ggccgggcca ctcacgttca 1150

 atggtacatc tgggtctcta tgtggttctg cagctcttcc tttgtttcaa 1200

 gaggatttgc aattgctcat tgaagcattc ttatgatggc tgctttataa 1250

 tccttgtcag atattaataa ttccaactcc tgattcatgt tggtgttggc 1300

 atcagttgat tatcttttct cattaaaatt gtgatgctcc taaaaaaaaa 1350

 aaaaaaaaa 1359

<210> 3970
<211> 344
<212> PRT
<213> Homo sapien

<400> 3970
 Met Gly Glu Asn Asp Pro Pro Ala Val Glu Ala Pro Phe Ser Phe
   1               5                  10                  15

 Arg Ser Leu Phe Gly Leu Asp Asp Leu Lys Ile Ser Pro Val Ala
                  20                  25                  30

 Pro Asp Ala Asp Ala Val Ala Ala Gln Ile Leu Ser Leu Leu Pro
                  35                  40                  45

 Leu Lys Phe Phe Pro Ile Ile Val Ile Gly Ile Ile Ala Leu Ile
                  50                  55                  60

 Leu Ala Leu Ala Ile Gly Leu Gly Ile His Phe Asp Cys Ser Gly
                  65                  70                  75

 Lys Tyr Arg Cys Arg Ser Ser Phe Lys Cys Ile Glu Leu Ile Ala
                  80                  85                  90

 Arg Cys Asp Gly Val Ser Asp Cys Lys Asp Gly Glu Asp Glu Tyr
                  95                 100                 105

 Arg Cys Val Arg Val Gly Gly Gln Asn Ala Val Leu Gln Val Phe
                 110                 115                 120

 Thr Ala Ala Ser Trp Lys Thr Met Cys Ser Asp Asp Trp Lys Gly
                 125                 130                 135

 His Tyr Ala Asn Val Ala Cys Ala Gln Leu Gly Phe Pro Ser Tyr
                 140                 145                 150

 Val Ser Ser Asp Asn Leu Arg Val Ser Ser Leu Glu Gly Gln Phe
                 155                 160                 165

 Arg Glu Glu Phe Val Ser Ile Asp His Leu Leu Pro Asp Asp Lys
                 170                 175                 180

 Val Thr Ala Leu His His Ser Val Tyr Val Arg Glu Gly Cys Ala
                 185                 190                 195

 Ser Gly His Val Val Thr Leu Gln Cys Thr Ala Cys Gly His Arg
                 200                 205                 210

 Arg Gly Tyr Ser Ser Arg Ile Val Gly Gly Asn Met Ser Leu Leu
                 215                 220                 225

 Ser Gln Trp Pro Trp Gln Ala Ser Leu Gln Phe Gln Gly Tyr His
                 230                 235                 240

 Leu Cys Gly Gly Ser Val Ile Thr Pro Leu Trp Ile Ile Thr Ala
                 245                 250                 255

 Ala His Cys Val Tyr Asp Leu Tyr Leu Pro Lys Ser Trp Thr Ile
                 260                 265                 270

 Gln Val Gly Leu Val Ser Leu Leu Asp Asn Pro Ala Pro Ser His
                 275                 280                 285

 Leu Val Glu Lys Ile Val Tyr His Ser Lys Tyr Lys Pro Lys Arg
                 290                 295                 300

 Leu Gly Asn Asp Ile Ala Leu Met Lys Leu Ala Gly Pro Leu Thr
                 305                 310                 315

 Phe Asn Gly Thr Ser Gly Ser Leu Cys Gly Ser Ala Ala Leu Pro
                 320                 325                 330

 Leu Phe Gln Glu Asp Leu Gln Leu Leu Ile Glu Ala Phe Leu
                 335                 340

<210> 3971
<211> 2192
<212> DNA
<213> Homo sapien

<400> 3971
 tccctgtcct gcgcccgcgc gccccgggag cctacccagc acgcgctccg 50

 cgcccactgg ttccctccag ccgccgccgt ccagccgagt ccccactccg 100

 gagtcgccgc tgccgcgggg acatggtcct ctgcgttcag gggtgagcac 150

 ccccttgtaa gctcagggct actgttgggt gtcagggaac aaagttttag 200

 actgctgcgc tccaaagcgg gcacacacat gtacctagaa cacaccagcc 250

 actgtcccca ccatgatgat gacacagcca tggacacacc cctgcccaga 300

 cctcgtcctt tgctggctgt ggagcggact gggcagcggc ccctgtgggc 350

 cccgtccctg gaactgccca agccagtcat gcagcccttg cctgctgggg 400

 ccttcctcga ggaggtggca gagggtaccc cagcccagac agagagtgag 450

 ccaaaggtgc tggacccaga ggaggatctg ctgtgcatag ccaagacctt 500

 ctcctacctt cgggaatctg gctggtattg gggttccatt acggccagcg 550

 aggcccgaca acacctgcag aagatgccag aaggcacgtt cttagtacgt 600

 gacagcacgc accccagcta cctgttcacg ctgtcagtga aaaccactcg 650

 tggccccacc aatgtacgca ttgagtatgc cgactccagc ttccgtctgg 700

 actccaactg cttgtccagg ccacgcatcc tggcctttcc ggatgtggtc 750

 agccttgtgc agcactatgt ggcctcctgc actgctgata cccgaagcga 800

 cagccccgat cctgctccca ccccggccct gcctatgcct aaggaggatg 850

 cgcctagtga cccagcactg cctgctcctc caccagccac tgctgtacac 900

 ctaaaactgg tgcagccctt tgtacgcaga agcagtgccc gcagcctgca 950

 acacctgtgc cgccttgtca tcaaccgtct ggtggccgac gtggactgcc 1000

 tgccactgcc ccggcgcatg gccgactacc tccgacagta ccccttccag 1050

 ctctgactgt acggggcaat ctgcccaccc tcacccagtc gcaccctgga 1100

 ggggacatca gccccagctg gacttgggcc cccactgtcc ctcctccagg 1150

 catcctggtg cctgcatacc tctggcagct ggcccaggaa gagccagcaa 1200

 gagcaaggca tgggagaggg gaggtgtcac acaacttgga ggtaaatgcc 1250

 cccaggccgc atgtggcttc attatactga gccatgtgtc agaggatggg 1300

 gagacaggca ggaccttgtc tcacctgtgg gctgggccca gacctccact 1350

 cgcttgcctg ccctggccac ctgaactgta tgggcactct cagccctggt 1400

 ttttcaatcc ccagggtcgg gtaggacccc tactggcagc cagcctctgt 1450

 ttctgggagg atgacatgca gaggaactga gatcgacagt gactagtgac 1500

 cccttgttga ggggtaagcc aggctagggg actgcacaat tatacactat 1550

 ttatttattt attctccttg gggttggtgt caggggcgag ccaaccccac 1600

 ctctatgccc tgagccctgg tagtccagag accccaactc tgccctggct 1650

 tctctggttc ttccctgtgg aaagcccatc ctgagacatc ttgctggaac 1700

 caaggcaatc ctggatgtcc tggtactgac ccacccgtct gtgaatgtgt 1750

 ccactctctt ctgcccccag ccatatttgg ggaggatgga caactacaat 1800

 aggtaagaaa atgcagccgg agcctcagtc cccagcagag cctgtgtctc 1850

 accccctcac aggacagagc tgtatctgca tagagctggt ctcactgtgg 1900

 cgcaggcccc ggggggagtg cctgtgctgt caggaagagg gggtgctggt 1950

 ttgagggcca ccactgcagt tctgctaggt ctgcttcctg cccaggaagg 2000

 tgcctgcaca tgagaggaga gaaatacacg tctgataaga cttcatgaaa 2050

 taataattat agcaaagaac agtttggtgg tcttttctct tccactgatt 2100

 tttctgtaat gacattatac ctttattacc tctttatttt attacctcta 2150

 taataaaatg ataccttttt catgtaaaaa aaaaaaaaaa aa 2192

<210> 3972
<211> 258
<212> PRT
<213> Homo sapien

<400> 3972
 Met Asp Thr Pro Leu Pro Arg Pro Arg Pro Leu Leu Ala Val Glu
   1               5                  10                  15

 Arg Thr Gly Gln Arg Pro Leu Trp Ala Pro Ser Leu Glu Leu Pro
                  20                  25                  30

 Lys Pro Val Met Gln Pro Leu Pro Ala Gly Ala Phe Leu Glu Glu
                  35                  40                  45

 Val Ala Glu Gly Thr Pro Ala Gln Thr Glu Ser Glu Pro Lys Val
                  50                  55                  60

 Leu Asp Pro Glu Glu Asp Leu Leu Cys Ile Ala Lys Thr Phe Ser
                  65                  70                  75

 Tyr Leu Arg Glu Ser Gly Trp Tyr Trp Gly Ser Ile Thr Ala Ser
                  80                  85                  90

 Glu Ala Arg Gln His Leu Gln Lys Met Pro Glu Gly Thr Phe Leu
                  95                 100                 105

 Val Arg Asp Ser Thr His Pro Ser Tyr Leu Phe Thr Leu Ser Val
                 110                 115                 120

 Lys Thr Thr Arg Gly Pro Thr Asn Val Arg Ile Glu Tyr Ala Asp
                 125                 130                 135

 Ser Ser Phe Arg Leu Asp Ser Asn Cys Leu Ser Arg Pro Arg Ile
                 140                 145                 150

 Leu Ala Phe Pro Asp Val Val Ser Leu Val Gln His Tyr Val Ala
                 155                 160                 165

 Ser Cys Thr Ala Asp Thr Arg Ser Asp Ser Pro Asp Pro Ala Pro
                 170                 175                 180

 Thr Pro Ala Leu Pro Met Pro Lys Glu Asp Ala Pro Ser Asp Pro
                 185                 190                 195

 Ala Leu Pro Ala Pro Pro Pro Ala Thr Ala Val His Leu Lys Leu
                 200                 205                 210

 Val Gln Pro Phe Val Arg Arg Ser Ser Ala Arg Ser Leu Gln His
                 215                 220                 225

 Leu Cys Arg Leu Val Ile Asn Arg Leu Val Ala Asp Val Asp Cys
                 230                 235                 240

 Leu Pro Leu Pro Arg Arg Met Ala Asp Tyr Leu Arg Gln Tyr Pro
                 245                 250                 255

 Phe Gln Leu


<210> 3973
<211> 2359
<212> DNA
<213> Homo sapien

<400> 3973
 gttttgcctg ctagcatctc cctgtaactc tcccaatctt gaggagtgat 50

 ccctgtccca gcccctggaa aggggcagga acgacaaact caaagtccag 100

 gatgttcacc atgacaagag ccatggaaga ggctcttttt cagcacttca 150

 tgcaccagaa gctggggatc gcctatgcca tacacaagcc atttcccttc 200

 tttgaaggcc tcctagacaa ctccatcatc actaagagaa tgtacatgga 250

 atctctggaa gcctgtagaa atttgatccc tgtatccaga gtggtgcaca 300

 acattctcac ccaactggag aggactttta acctgtctct tctggtgaca 350

 ttgttcagtc aaattaacct gcgtgaatat cccaatctgg tgacgattta 400

 cagaagcttc aaacgtgttg gtgcttccta tgaacggcag agcagagaca 450

 caccaatcct acttgaagcc ccaactggcc tagcagaagg aagctccctc 500

 cataccccac tggcgctgcc cccaccacaa ccccctcaac caagctgttc 550

 accctgtgcg ccaagagtca gtgagcctgg aacatcctcc cagcaaagcg 600

 atgagatcct gagtgagtcg cccagcccat ctgaccctgt cctgcctctc 650

 cctgcactca tccaggaagg aagaagcact tcagtgacca atgacaagtt 700

 aacatccaaa atgaatgcgg aagaagactc agaagagatg cccagcctcc 750

 tcactagcac tgtgcaagtg gccagtgaca acctgatccc ccaaataaga 800

 gataaagaag accctcaaga gatgccccac tctcccttgg gctctatgcc 850

 agagataaga gataattctc cagaaccaaa tgacccagaa gagccccagg 900

 aggtgtccag cacaccttca gacaagaaag gaaagaaaag aaaaagatgt 950

 atctggtcaa ctccaaaaag gagacataag aaaaaaagcc tcccaagagg 1000

 gacagcctca tctagacacg gaatccaaaa gaagctcaaa agggtggatc 1050

 aggttcctca aaagaaagat gactcaactt gtaactccac ggtagagaca 1100

 agggcccaaa aggcgagaac tgaatgtgcc cgaaagtcga gatcagagga 1150

 gatcattgat ggcacttcag aaatgaatga aggaaagagg tcccagaaga 1200

 cgcctagtac accacgaagg gtcacacaag gggcagcctc acctgggcat 1250

 ggcatccaag agaagctcca agtggtggat aaggtgactc aaaggaaaga 1300

 cgactcaacc tggaactcag aggtcatgat gagggtccaa aaggcaagaa 1350

 ctaaatgtgc ccgaaagtcc agatcgaaag aaaagaaaaa ggagaaagat 1400

 atctgttcaa gctcaaaaag gagatttcag aaaaatattc accgaagagg 1450

 aaaacccaaa agtgacactg tggattttca ctgttctaag ctccccgtga 1500

 cctgtggtga ggcgaaaggg attttatata agaagaaaat gaaacacgga 1550

 tcctcagtga agtgcattcg gaatgaggat ggaacttggt taacaccaaa 1600

 tgaatttgaa gtcgaaggaa aaggaaggaa cgcaaagaac tggaaacgga 1650

 atatacgttg tgaaggaatg accctaggag agctgctgaa gcggaaaaac 1700

 tcggatgaat gcgaggtgtg ctgtcaaggg ggacaacttc tctgctgcgg 1750

 tacttgtcca cgagtcttcc atgaggactg tcacatcccc cctgtggaag 1800

 ccaagaggat gctgtggagt tgcaccttct gcaggatgaa gaggtcttca 1850

 ggaagccaac agtgccatca tgtatctaag accctggaga ggcagatgca 1900

 gcctcaggac cagctgattc gagattacgg tgagcccttt caggaagcaa 1950

 tgtggttgga cctggttaag gaaaggctga ttacggaaat gtacacggtg 2000

 gcatggtttg tgcgagacat gcgcctgatg tttcgcaacc ataaaacatt 2050

 ttacaaggct tctgactttg gccaggtagg acttgactta gaggcagaat 2100

 ttgaaaaaga tctcaaagac gtgctcggtt ttcatgaagc caatgacggc 2150

 ggtttctgga ctcttccttg accctgttct gtaaagactg aagcatcccc 2200

 acctcaggat tcagctgatg ggaccctggc ttggactgtt gattgccagt 2250

 gagtctggga tgtaattggc tgccctcagg acccaaaccc agacacttca 2300

 taggattatc acaccctcca tctttattct ttctttttac ctttaaaagt 2350

 ctatatcta 2359

<210> 3974
<211> 689
<212> PRT
<213> Homo sapien

<400> 3974
 Met Phe Thr Met Thr Arg Ala Met Glu Glu Ala Leu Phe Gln His
   1               5                  10                  15

 Phe Met His Gln Lys Leu Gly Ile Ala Tyr Ala Ile His Lys Pro
                  20                  25                  30

 Phe Pro Phe Phe Glu Gly Leu Leu Asp Asn Ser Ile Ile Thr Lys
                  35                  40                  45

 Arg Met Tyr Met Glu Ser Leu Glu Ala Cys Arg Asn Leu Ile Pro
                  50                  55                  60

 Val Ser Arg Val Val His Asn Ile Leu Thr Gln Leu Glu Arg Thr
                  65                  70                  75

 Phe Asn Leu Ser Leu Leu Val Thr Leu Phe Ser Gln Ile Asn Leu
                  80                  85                  90

 Arg Glu Tyr Pro Asn Leu Val Thr Ile Tyr Arg Ser Phe Lys Arg
                  95                 100                 105

 Val Gly Ala Ser Tyr Glu Arg Gln Ser Arg Asp Thr Pro Ile Leu
                 110                 115                 120

 Leu Glu Ala Pro Thr Gly Leu Ala Glu Gly Ser Ser Leu His Thr
                 125                 130                 135

 Pro Leu Ala Leu Pro Pro Pro Gln Pro Pro Gln Pro Ser Cys Ser
                 140                 145                 150

 Pro Cys Ala Pro Arg Val Ser Glu Pro Gly Thr Ser Ser Gln Gln
                 155                 160                 165

 Ser Asp Glu Ile Leu Ser Glu Ser Pro Ser Pro Ser Asp Pro Val
                 170                 175                 180

 Leu Pro Leu Pro Ala Leu Ile Gln Glu Gly Arg Ser Thr Ser Val
                 185                 190                 195

 Thr Asn Asp Lys Leu Thr Ser Lys Met Asn Ala Glu Glu Asp Ser
                 200                 205                 210

 Glu Glu Met Pro Ser Leu Leu Thr Ser Thr Val Gln Val Ala Ser
                 215                 220                 225

 Asp Asn Leu Ile Pro Gln Ile Arg Asp Lys Glu Asp Pro Gln Glu
                 230                 235                 240

 Met Pro His Ser Pro Leu Gly Ser Met Pro Glu Ile Arg Asp Asn
                 245                 250                 255

 Ser Pro Glu Pro Asn Asp Pro Glu Glu Pro Gln Glu Val Ser Ser
                 260                 265                 270

 Thr Pro Ser Asp Lys Lys Gly Lys Lys Arg Lys Arg Cys Ile Trp
                 275                 280                 285

 Ser Thr Pro Lys Arg Arg His Lys Lys Lys Ser Leu Pro Arg Gly
                 290                 295                 300

 Thr Ala Ser Ser Arg His Gly Ile Gln Lys Lys Leu Lys Arg Val
                 305                 310                 315

 Asp Gln Val Pro Gln Lys Lys Asp Asp Ser Thr Cys Asn Ser Thr
                 320                 325                 330

 Val Glu Thr Arg Ala Gln Lys Ala Arg Thr Glu Cys Ala Arg Lys
                 335                 340                 345

 Ser Arg Ser Glu Glu Ile Ile Asp Gly Thr Ser Glu Met Asn Glu
                 350                 355                 360

 Gly Lys Arg Ser Gln Lys Thr Pro Ser Thr Pro Arg Arg Val Thr
                 365                 370                 375

 Gln Gly Ala Ala Ser Pro Gly His Gly Ile Gln Glu Lys Leu Gln
                 380                 385                 390

 Val Val Asp Lys Val Thr Gln Arg Lys Asp Asp Ser Thr Trp Asn
                 395                 400                 405

 Ser Glu Val Met Met Arg Val Gln Lys Ala Arg Thr Lys Cys Ala
                 410                 415                 420

 Arg Lys Ser Arg Ser Lys Glu Lys Lys Lys Glu Lys Asp Ile Cys
                 425                 430                 435

 Ser Ser Ser Lys Arg Arg Phe Gln Lys Asn Ile His Arg Arg Gly
                 440                 445                 450

 Lys Pro Lys Ser Asp Thr Val Asp Phe His Cys Ser Lys Leu Pro
                 455                 460                 465

 Val Thr Cys Gly Glu Ala Lys Gly Ile Leu Tyr Lys Lys Lys Met
                 470                 475                 480

 Lys His Gly Ser Ser Val Lys Cys Ile Arg Asn Glu Asp Gly Thr
                 485                 490                 495

 Trp Leu Thr Pro Asn Glu Phe Glu Val Glu Gly Lys Gly Arg Asn
                 500                 505                 510

 Ala Lys Asn Trp Lys Arg Asn Ile Arg Cys Glu Gly Met Thr Leu
                 515                 520                 525

 Gly Glu Leu Leu Lys Arg Lys Asn Ser Asp Glu Cys Glu Val Cys
                 530                 535                 540

 Cys Gln Gly Gly Gln Leu Leu Cys Cys Gly Thr Cys Pro Arg Val
                 545                 550                 555

 Phe His Glu Asp Cys His Ile Pro Pro Val Glu Ala Lys Arg Met
                 560                 565                 570

 Leu Trp Ser Cys Thr Phe Cys Arg Met Lys Arg Ser Ser Gly Ser
                 575                 580                 585

 Gln Gln Cys His His Val Ser Lys Thr Leu Glu Arg Gln Met Gln
                 590                 595                 600

 Pro Gln Asp Gln Leu Ile Arg Asp Tyr Gly Glu Pro Phe Gln Glu
                 605                 610                 615

 Ala Met Trp Leu Asp Leu Val Lys Glu Arg Leu Ile Thr Glu Met
                 620                 625                 630

 Tyr Thr Val Ala Trp Phe Val Arg Asp Met Arg Leu Met Phe Arg
                 635                 640                 645

 Asn His Lys Thr Phe Tyr Lys Ala Ser Asp Phe Gly Gln Val Gly
                 650                 655                 660

 Leu Asp Leu Glu Ala Glu Phe Glu Lys Asp Leu Lys Asp Val Leu
                 665                 670                 675

 Gly Phe His Glu Ala Asn Asp Gly Gly Phe Trp Thr Leu Pro
                 680                 685

<210> 3975
<211> 885
<212> DNA
<213> Homo sapien

<400> 3975
 gccgcttttt tttttttttt ttttttttga aggaaaattt gtattatttc 50

 aattattttt atgtacagaa aactcaacag tgtacattta acccagttta 100

 gtggcaagtt ctttagcctt tgccttttcg agcttggcga tacgagccac 150

 agacttagga cccaggacat tgccacccca gtgacggcgg atctcatcgt 200

 atctgtcatt gtaattggtc ctgatagctt ccaccagctt agccaaagcg 250

 cctttgtctt ccgagttcac ctgtgtgaag gcgacagtgg tgcaggtctt 300

 cctgtggact agacgtccca gtcttgcctt tcagctttca cttctgccgg 350

 ctccgcaact gagtgacacc cagcgacaac cgactgggga gtggtagaag 400

 caactgaacg gatgcgtgcg agctgaggac agggcgggag gagggggcac 450

 acatgcccca ggggagcgag gagaactctt gaaatctcca ttttcaatcc 500

 cttcgaaatc acgtatggtt tccacaaagc cgagtcgtgt cacgtggcag 550

 gtttacgtca atagtccctc tctctgctcc tccattcgca agtgtcttcc 600

 tgggccagac tcccctccac ctcatgtact tgctatattg aggatgaagt 650

 tttctatggt gggacactaa atataaagct atatagagaa aaaaaaaaaa 700

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa caaaaaaaaa 850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 885

<210> 3976
<211> 83
<212> PRT
<213> Homo sapien

<400> 3976
 Met Tyr Arg Lys Leu Asn Ser Val His Leu Thr Gln Phe Ser Gly
   1               5                  10                  15

 Lys Phe Phe Ser Leu Cys Leu Phe Glu Leu Gly Asp Thr Ser His
                  20                  25                  30

 Arg Leu Arg Thr Gln Asp Ile Ala Thr Pro Val Thr Ala Asp Leu
                  35                  40                  45

 Ile Val Ser Val Ile Val Ile Gly Pro Asp Ser Phe His Gln Leu
                  50                  55                  60

 Ser Gln Ser Ala Phe Val Phe Arg Val His Leu Cys Glu Gly Asp
                  65                  70                  75

 Ser Gly Ala Gly Leu Pro Val Asp
                  80

<210> 3977
<211> 1739
<212> DNA
<213> Homo sapien

<400> 3977
 ggggatcact gttggaaggc agctgcttga ggtccaaggc agtcagtgtc 50

 ccctctcttt tgcctcggga cagctggtat ttatcagact cctaagaagt 100

 tttccttgct ccctagtaga agagagagat tatgcagcgg gcttttgatt 150

 gatccaatgg gaattacatt gatctggtgt ctggccttgg ttcttatcaa 200

 gtggatcacc tctaagaggc gtggagctat ttcctatgac agttctgatc 250

 agactgcatt atacattcgt atgctaggag atgtacgtgt aaggagccga 300

 gcaggatttg aatcagaaag aagaggttct cacccatata ttgattttcg 350

 tattttccac tctcaatctg aaattgaagt gtctgtctct gcaaggaata 400

 tcagaaggct actaagtttc cagcgatatc ttagatcttc acgctttttt 450

 cgtggtactg cggtttcaaa ttccctaaac attttagatg atgattataa 500

 tggacaagcc aagtgtatgc tggaaaaagt tggaaattgg aattttgata 550

 tctttctatt tgatagacta acaaatggaa atagtctagt aagcttaacc 600

 tttcatttat ttagtcttca tggattaatt gagtacttcc atttagatat 650

 gatgaaactt cgtagatttt tagttatgat tcaagaagat taccacagtc 700

 aaaatcctta ccataacgca gtccacgctg cggatgttac tcaggccatg 750

 cactgttact taaaggaacc taagcttgcc aattctgtaa ctccttggga 800

 tatcttgctg agcttaattg cagctgccac tcatgatctg gatcatccag 850

 gtgttaatca acctttcctt attaaaacta accattactt ggcaacttta 900

 tacaagaata cctcagtact ggaaaatcac cactggagat ctgcagtggg 950

 cttattgaga gaatcaggct tattctcaca tctgccatta gaaagcaggc 1000

 aacaaatgga gacacagata ggtgctctga tactagccac agacatcagt 1050

 cgccagaatg agtatctgtc tttgtttagg tcccatttgg atagaggtga 1100

 tttatgccta gaagacacca gacacagaca tttggtttta cagatggctt 1150

 tgaaatgtgc tgatatttgt aacccatgtc ggacgtggga attaagcaag 1200

 cagtggagtg aaaaagtaac ggaggaattc ttccatcaag gagatataga 1250

 aaaaaaatat catttgggtg tgagtccact ttgcgatcgt cacactgaat 1300

 ctattgccaa catccagatt ggttttatga cttacctagt ggagccttta 1350

 tttacagaat gggccaggtt ttccaataca aggctatccc agacaatgct 1400

 tggacacgtg gggctgaata aagccagctg gaagggactg cagagagaac 1450

 agtcgagcag tgaggacact gatgctgcat ttgagttgaa ctcacagtta 1500

 ttacctcagg aaaatcggtt atcataaccc ccagaaccag tgggacaaac 1550

 tgcctcctgg aggtttttag aaatgtgaaa tggggtcttg aggtgagaga 1600

 acttaactct tgactgccaa ggtttccaag tgagtgatgc cagccagcat 1650

 tatttatttc caagatttcc tctgttggat catttgaacc cacttgttaa 1700

 ttgcaagacc cgaacataca gcaatatgaa tttggcttt 1739

<210> 3978
<211> 456
<212> PRT
<213> Homo sapien

<400> 3978
 Met Gly Ile Thr Leu Ile Trp Cys Leu Ala Leu Val Leu Ile Lys
   1               5                  10                  15

 Trp Ile Thr Ser Lys Arg Arg Gly Ala Ile Ser Tyr Asp Ser Ser
                  20                  25                  30

 Asp Gln Thr Ala Leu Tyr Ile Arg Met Leu Gly Asp Val Arg Val
                  35                  40                  45

 Arg Ser Arg Ala Gly Phe Glu Ser Glu Arg Arg Gly Ser His Pro
                  50                  55                  60

 Tyr Ile Asp Phe Arg Ile Phe His Ser Gln Ser Glu Ile Glu Val
                  65                  70                  75

 Ser Val Ser Ala Arg Asn Ile Arg Arg Leu Leu Ser Phe Gln Arg
                  80                  85                  90

 Tyr Leu Arg Ser Ser Arg Phe Phe Arg Gly Thr Ala Val Ser Asn
                  95                 100                 105

 Ser Leu Asn Ile Leu Asp Asp Asp Tyr Asn Gly Gln Ala Lys Cys
                 110                 115                 120

 Met Leu Glu Lys Val Gly Asn Trp Asn Phe Asp Ile Phe Leu Phe
                 125                 130                 135

 Asp Arg Leu Thr Asn Gly Asn Ser Leu Val Ser Leu Thr Phe His
                 140                 145                 150

 Leu Phe Ser Leu His Gly Leu Ile Glu Tyr Phe His Leu Asp Met
                 155                 160                 165

 Met Lys Leu Arg Arg Phe Leu Val Met Ile Gln Glu Asp Tyr His
                 170                 175                 180

 Ser Gln Asn Pro Tyr His Asn Ala Val His Ala Ala Asp Val Thr
                 185                 190                 195

 Gln Ala Met His Cys Tyr Leu Lys Glu Pro Lys Leu Ala Asn Ser
                 200                 205                 210

 Val Thr Pro Trp Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala Thr
                 215                 220                 225

 His Asp Leu Asp His Pro Gly Val Asn Gln Pro Phe Leu Ile Lys
                 230                 235                 240

 Thr Asn His Tyr Leu Ala Thr Leu Tyr Lys Asn Thr Ser Val Leu
                 245                 250                 255

 Glu Asn His His Trp Arg Ser Ala Val Gly Leu Leu Arg Glu Ser
                 260                 265                 270

 Gly Leu Phe Ser His Leu Pro Leu Glu Ser Arg Gln Gln Met Glu
                 275                 280                 285

 Thr Gln Ile Gly Ala Leu Ile Leu Ala Thr Asp Ile Ser Arg Gln
                 290                 295                 300

 Asn Glu Tyr Leu Ser Leu Phe Arg Ser His Leu Asp Arg Gly Asp
                 305                 310                 315

 Leu Cys Leu Glu Asp Thr Arg His Arg His Leu Val Leu Gln Met
                 320                 325                 330

 Ala Leu Lys Cys Ala Asp Ile Cys Asn Pro Cys Arg Thr Trp Glu
                 335                 340                 345

 Leu Ser Lys Gln Trp Ser Glu Lys Val Thr Glu Glu Phe Phe His
                 350                 355                 360

 Gln Gly Asp Ile Glu Lys Lys Tyr His Leu Gly Val Ser Pro Leu
                 365                 370                 375

 Cys Asp Arg His Thr Glu Ser Ile Ala Asn Ile Gln Ile Gly Phe
                 380                 385                 390

 Met Thr Tyr Leu Val Glu Pro Leu Phe Thr Glu Trp Ala Arg Phe
                 395                 400                 405

 Ser Asn Thr Arg Leu Ser Gln Thr Met Leu Gly His Val Gly Leu
                 410                 415                 420

 Asn Lys Ala Ser Trp Lys Gly Leu Gln Arg Glu Gln Ser Ser Ser
                 425                 430                 435

 Glu Asp Thr Asp Ala Ala Phe Glu Leu Asn Ser Gln Leu Leu Pro
                 440                 445                 450

 Gln Glu Asn Arg Leu Ser
                 455

<210> 3979
<211> 3105
<212> DNA
<213> Homo sapien

<400> 3979
 agcgcagcgt gcgggtggcc tggatcccgc gcagtggccc ggcgatgtcg 50

 ctcgtgctgc taagcctggc cgcgctgtgc aggagcgccg taccccgaga 100

 gccgaccgtt caatgtggct ctgaaactgg gccatctcca gagtggatgc 150

 tacaacatga tctaatcccc ggagacttga gggacctccg agtagaacct 200

 gttacaacta gtgttgcaac aggggactat tcaattttga tgaatgtaag 250

 ctgggtactc cgggcagatg ccagcatccg cttgttgaag gccaccaaga 300

 tttgtgtgac gggcaaaagc aacttccagt cctacagctg tgtgaggtgc 350

 aattacacag aggccttcca gactcagacc agaccctctg gtggtaaatg 400

 gacattttcc tacatcggct tccctgtaga gctgaacaca gtctatttca 450

 ttggggccca taatattcct aatgcaaata tgaatgaaga tggcccttcc 500

 atgtctgtga atttcacctc accaggctgc ctagaccaca taatgaaata 550

 taaaaaaaag tgtgtcaagg ccggaagcct gtgggatccg aacatcactg 600

 cttgtaagaa gaatgaggag acagtagaag tgaacttcac aaccactccc 650

 ctgggaaaca gatacatggc tcttatccaa cacagcacta tcatcgggtt 700

 ttctcaggtg tttgagccac accagaagaa acaaacgcga gcttcagtgg 750

 tgattccagt gactggggat agtgaaggtg ctacggtgca ggtaaagttc 800

 agtgagctgc tctggggagg gaagggacat agaagactgt tccatcattc 850

 attgctttta aggatgagtt ctctcttgtc aaatgcactt ctgccagcag 900

 acaccagtta agtggcgttc atgggggctc tttcgctgca gcctccaccg 950

 tgctgaggtc aggaggccga cgtggcagtt gtggtccctt ttgcttgtat 1000

 taatggctgc tgaccttcca aagcactttt tattttcatt ttctgtcaca 1050

 gacactcagg gatagcagta ccattttact tccgcaagcc tttaactgca 1100

 agatgaagct gcaaagggtt tgaaatggga aggtttgagt tccaggcagc 1150

 gtatgaactc tggagagggg ctgccagtcc tctctgggcc gcagcggacc 1200

 cagctggaac acaggaagtt ggagcagtag gtgctccttc acctctcagt 1250

 atgtctcttt caactctagt ttttgaggtg gggacacagg aggtccagtg 1300

 ggacacagcc actccccaaa gagtaaggag cttccatgct tcattccctg 1350

 gcataaaaag tgctcaaaca caccagaggg ggcaggcacc agccagggta 1400

 tgatggctac tacccttttc tggagaacca tagacttccc ttactacagg 1450

 gacttgcatg tcctaaagca ctggctgaag gaagccaaga ggatcactgc 1500

 tgctcctttt ttctagagga aatgtttgtc tacgtggtaa gatatgacct 1550

 agccctttta ggtaagcgaa ctggtatgtt agtaacgtgt acaaagttta 1600

 ggttcagacc ccgggagtct tgggcacgtg ggtctcgggt cactggtttt 1650

 gactttaggg ctttgttaca gatgtgtgac caaggggaaa atgtgcatga 1700

 caacactaga ggtatgggcg aagccagaaa gaagggaagt tttggctgaa 1750

 gtaggagtct tggtgagatt ttgctctgat gcatggtgtg aactttctga 1800

 gcctcttgtt tttcctcagc tgactccata ttttcctact tgtggcagcg 1850

 actgcatccg acataaagga acagttgtgc tctgcccaca aacaggcgtc 1900

 cctttccctc tggataacaa caaaagcaag ccgggaggct ggctgcctct 1950

 cctcctgctg tctctgctgg tggccacatg ggtgctggtg gcagggatct 2000

 atctaatgtg gaggcacgaa aggatcaaga agacttcctt ttctaccacc 2050

 acactactgc cccccattaa ggttcttgtg gtttacccat ctgaaatatg 2100

 tttccatcac acaatttgtt acttcactga atttcttcaa aaccattgca 2150

 gaagtgaggt catccttgaa aagtggcaga aaaagaaaat agcagagatg 2200

 ggtccagtgc agtggcttgc cactcaaaag aaggcagcag acaaagtcgt 2250

 cttccttctt tccaatgacg tcaacagtgt gtgcgatggt acctgtggca 2300

 agagcgaggg cagtcccagt gagaactctc aagacctctt cccccttgcc 2350

 tttaaccttt tctgcagtga tctaagaagc cagattcatc tgcacaaata 2400

 cgtggtggtc tactttagag agattgatac aaaagacgat tacaatgctc 2450

 tcagtgtctg ccccaagtac cacctcatga aggatgccac tgctttctgt 2500

 gcagaacttc tccatgtcaa gcagcaggtg tcagcaggaa aaagatcaca 2550

 agcctgccac gatggctgct gctccttgta gcccacccat gagaagcaag 2600

 agaccttaaa ggcttcctat cccaccaatt acagggaaaa aacgtgtgat 2650

 gatcctgaag cttactatgc agcctacaaa cagccttagt aattaaaaca 2700

 ttttatacca ataaaatttt caaatattgc taactaatgt agcattaact 2750

 aacgattgga aactacattt acaacttcaa agctgtttta tacatagaaa 2800

 tcaattacag ttttaattga aaactataac cattttgata atgcaacaat 2850

 aaagcatctt cagccaaaca tctagtcttc catagaccat gcattgcagt 2900

 gtacccagaa ctgtttagct aatattctat gtttaattaa tgaatactaa 2950

 ctctaagaac ccctcactga ttcactcaat agcatcttaa gtgaaaaacc 3000

 ttctattaca tgcaaaaaat cattgttttt aagataacaa aagtagggaa 3050

 taaacaagct gaacccactt ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3100

 aaaaa 3105

<210> 3980
<211> 288
<212> PRT
<213> Homo sapien

<400> 3980
 Met Ser Leu Val Leu Leu Ser Leu Ala Ala Leu Cys Arg Ser Ala
   1               5                  10                  15

 Val Pro Arg Glu Pro Thr Val Gln Cys Gly Ser Glu Thr Gly Pro
                  20                  25                  30

 Ser Pro Glu Trp Met Leu Gln His Asp Leu Ile Pro Gly Asp Leu
                  35                  40                  45

 Arg Asp Leu Arg Val Glu Pro Val Thr Thr Ser Val Ala Thr Gly
                  50                  55                  60

 Asp Tyr Ser Ile Leu Met Asn Val Ser Trp Val Leu Arg Ala Asp
                  65                  70                  75

 Ala Ser Ile Arg Leu Leu Lys Ala Thr Lys Ile Cys Val Thr Gly
                  80                  85                  90

 Lys Ser Asn Phe Gln Ser Tyr Ser Cys Val Arg Cys Asn Tyr Thr
                  95                 100                 105

 Glu Ala Phe Gln Thr Gln Thr Arg Pro Ser Gly Gly Lys Trp Thr
                 110                 115                 120

 Phe Ser Tyr Ile Gly Phe Pro Val Glu Leu Asn Thr Val Tyr Phe
                 125                 130                 135

 Ile Gly Ala His Asn Ile Pro Asn Ala Asn Met Asn Glu Asp Gly
                 140                 145                 150

 Pro Ser Met Ser Val Asn Phe Thr Ser Pro Gly Cys Leu Asp His
                 155                 160                 165

 Ile Met Lys Tyr Lys Lys Lys Cys Val Lys Ala Gly Ser Leu Trp
                 170                 175                 180

 Asp Pro Asn Ile Thr Ala Cys Lys Lys Asn Glu Glu Thr Val Glu
                 185                 190                 195

 Val Asn Phe Thr Thr Thr Pro Leu Gly Asn Arg Tyr Met Ala Leu
                 200                 205                 210

 Ile Gln His Ser Thr Ile Ile Gly Phe Ser Gln Val Phe Glu Pro
                 215                 220                 225

 His Gln Lys Lys Gln Thr Arg Ala Ser Val Val Ile Pro Val Thr
                 230                 235                 240

 Gly Asp Ser Glu Gly Ala Thr Val Gln Val Lys Phe Ser Glu Leu
                 245                 250                 255

 Leu Trp Gly Gly Lys Gly His Arg Arg Leu Phe His His Ser Leu
                 260                 265                 270

 Leu Leu Arg Met Ser Ser Leu Leu Ser Asn Ala Leu Leu Pro Ala
                 275                 280                 285

 Asp Thr Ser


<210> 3981
<211> 10011
<212> DNA
<213> Homo sapien

<400> 3981
 ttcctccgcg aaggctcctt tgatattaat agtgttggtg tcttgaaact 50

 gacgtaatgc gcggagactg aggtcctgac aagcgataac atttctgata 100

 aagacccgat cttactgcaa tctctagcgt cctctttttt ggtgctgctg 150

 gtttctccag acctcgcgtc ctctcgattg ctctctcgcc ttcctatttc 200

 tttttttttt ttttaaacaa aaaacaacac cccctcccct ctcccacccg 250

 gcaccgggca catccttgct ctatttcctt tctctttctc tctctctctc 300

 tctctttttt aataagggtg ggggagggaa agggggggga ggcaggaaag 350

 acctttttct ctcccccccg caataatcca agatcaactc tgcaaacaac 400

 agaagacggt tcatggcttt ggccgccgcg ccaccatctt tcgggctgcc 450

 gagggtgttc ttgacgatta atcaacagat gtacagatca gctctcaaaa 500

 tgtcttctgt gtcttctgag cgtcttctaa gacaattgca ttagcctcct 550

 gctagttgac taatagaatt aataattgta aaaagcactc taaagccaca 600

 tgccttatga agtcaatgct gggtatgatt ttacaaatat ggtccggaaa 650

 aagaaccccc ctctgagaaa cgttgcaagt gaaggcgagg gccagatcct 700

 ggagcctata ggtacagaaa gcaaggtatc tggaaagaac aaagaattct 750

 ctgcagatca gatgtcagaa aatacggatc agagtgatgc tgcagaacta 800

 aatcataagg aggaacatag cttgcatgtt caagatccat cttctagcag 850

 taagaaggac ttgaaaagcg cagttctgag tgagaaggct ggcttcaatt 900

 atgaaagccc cagtaaggga ggaaactttc cctcctttcc gcatgatgag 950

 gtgacagaca gaaatatgtt ggctttctca tttccagctg ctgggggagt 1000

 ctgtgagccc ttgaagtctc cgcaaagagc agaggcagat gaccctcaag 1050

 atatggcctg caccccctca ggggactcac tggagacaaa ggaagatcag 1100

 aagatgtcac caaaggctac agaggaaaca gggcaagcac agagtggtca 1150

 agccaattgt caaggtttga gcccagtttc agtggcctca aaaaacccac 1200

 aagtgccttc agatgggggt gtaagactga ataaatccaa aactgactta 1250

 ctggtgaatg acaacccaga cccggcacct ctgtctccag agcttcagga 1300

 ctttaaatgc aatatctgtg gatatggtta ctacggcaac gaccccacag 1350

 atctgattaa gcacttccga aagtatcact taggactgca taaccgcacc 1400

 aggcaagatg ctgagctgga cagcaaaatc ttggcccttc ataacatggt 1450

 gcagttcagc cattccaaag acttccagaa ggtcaaccgt tctgtgtttt 1500

 ctggtgtgct gcaggacatc aattcttcaa ggcctgtttt actaaatggg 1550

 acctatgatg tgcaggtgac ttcaggtgga acattcattg gcattggacg 1600

 gaaaacacca gattgccaag ggaacaccaa gtatttccgc tgtaaattct 1650

 gcaatttcac ttatatgggc aactcatcca ccgaattaga acaacatttt 1700

 cttcagactc acccaaacaa aataaaagct tctctcccct cctctgaggt 1750

 tgcaaaacct tcagagaaaa actctaacaa gtccatccct gcacttcaat 1800

 ccagtgattc tggagacttg ggaaaatggc aggacaagat aacagtcaaa 1850

 gcaggagatg acactcctgt tgggtactca gtgcccataa agcccctcga 1900

 ttcctctaga caaaatggta cagaggccac cagttactac tggtgtaaat 1950

 tttgtagttt cagctgtgag tcatctagct cacttaaact gctagaacat 2000

 tatggcaagc agcacggagc agtgcagtca ggcggcctta atccagagtt 2050

 aaatgataag ctttccaggg gctctgtcat taatcagaat gatctagcca 2100

 aaagttcaga aggagagaca atgaccaaga cagacaagag ctcgagtggg 2150

 gctaaaaaga aggacttctc cagcaaggga gccgaggata atatggtaac 2200

 gagctataat tgtcagttct gtgacttccg atattccaaa agccatggcc 2250

 ctgatgtaat tgtagtgggg ccacttctcc gtcattatca acagctccat 2300

 aacattcaca agtgtaccat taaacactgt ccattctgtc ccagaggact 2350

 ttgcagccca gaaaagcacc ttggagaaat tacttatccg tttgcttgta 2400

 gaaaaagtaa ttgttcccac tgtgcactct tgcttctgca cttgtctcct 2450

 ggggcggctg gaagctcgcg agtcaaacat cagtgccatc agtgttcatt 2500

 caccacccct gacgtagatg tactcctctt tcactatgaa agtgtgcatg 2550

 agtcccaagc atcggatgtc aaacaagaag caaatcacct gcaaggatcg 2600

 gatgggcagc agtctgtcaa ggaaagcaaa gaacactcat gtaccaaatg 2650

 tgattttatt acccaagtgg aagaagagat ttcccgacac tacaggagag 2700

 cacacagctg ctacaaatgc cgtcagtgca gttttacagc tgccgatact 2750

 cagtcactac tggagcactt caacactgtt cactgccagg aacaggacat 2800

 cactacagcc aacggcgaag aggacggtca tgccatatcc accatcaaag 2850

 aggagcccaa aattgacttc agggtctaca atctgctaac tccagactct 2900

 aaaatgggag agccagtttc tgagagtgtg gtgaagagag agaagctgga 2950

 agagaaggac gggctcaaag agaaagtttg gaccgagagt tccagtgatg 3000

 accttcgcaa tgtgacttgg agaggggcag acatcctgcg ggggagtccg 3050

 tcatacaccc aagcaagcct ggggctgctg acgcctgtgt ctggcaccca 3100

 agagcagaca aagactctaa gggatagtcc caatgtggag gccgcccatc 3150

 tggcgcgacc tatttatggc ttggctgtgg aaaccaaggg attcctgcag 3200

 ggggcgccag ctggcggaga gaagtctggg gccctccccc agcagtatcc 3250

 tgcatcggga gaaaacaagt ccaaggatga atcccagtcc ctgttacgga 3300

 ggcgtagagg ctccggtgtt ttttgtgcca attgcctgac cacaaagacc 3350

 tctctctggc gaaagaatgc aaatggcgga tatgtatgca acgcgtgtgg 3400

 cctctaccag aagcttcact cgactcccag gcctttaaac atcattaaac 3450

 aaaacaacgg tgagcagatt attaggagga gaacaagaaa gcgccttaac 3500

 ccagaggcac ttcaggctga gcagctcaac aaacagcaga ggggcagcaa 3550

 tgaggagcaa gtcaatggaa gcccgttaga gaggaggtca gaagatcatc 3600

 taactgaaag tcaccagaga gaaattccac tccccagcct aagtaaatac 3650

 gaagcccagg gttcattgac taaaagccat tctgctcagc agccagtcct 3700

 ggtcagccaa actctggata ttcacaaaag gatgcaacct ttgcacattc 3750

 agataaaaag tcctcaggaa agtactggag atccaggaaa tagttcatcc 3800

 gtatctgaag ggaaaggaag ttctgagaga ggcagtccta tagaaaagta 3850

 catgagacct gcgaaacacc caaattattc accaccaggc agccctattg 3900

 aaaagtacca gtacccactt tttggacttc cctttgtaca taatgacttc 3950

 cagagtgaag ctgattggct gcggttctgg agtaaatata agctctccgt 4000

 tcctgggaat ccgcactact tgagtcacgt gcctggccta ccaaatcctt 4050

 gccaaaacta tgtgccttat cccaccttca atctgcctcc tcatttttca 4100

 gctgttggat cagacaatga cattcctcta gatttggcga tcaagcattc 4150

 cagacctggg ccaactgcaa acggtgcctc caaggagaaa acgaaggcac 4200

 caccaaatgt aaaaaatgaa ggtcccttga atgtagtaaa aacagagaaa 4250

 gttgatagaa gtactcaaga tgaactttca acaaaatgtg tgcactgtgg 4300

 cattgtcttt ctggatgaag tgatgtatgc tttgcatatg agttgccatg 4350

 gtgacagtgg acctttccag tgcagcatat gccagcatct ttgcacggac 4400

 aaatatgact tcacaacaca tatccagagg ggcctgcata ggaacaatgc 4450

 acaagtggaa aaaaatggaa aacctaaaga gtaaaacctt agcacttagc 4500

 acaattaaat agaaataggt tttcttgatg ggaattcaat agcttgtaat 4550

 gtcttatgaa gacctattaa aaaaatactt catagagcct gccttatcca 4600

 acatgaaatt cccttctttt gttattcttt cttttgatga gtaggttacc 4650

 aagattaaaa agtgagataa atggtcaatg agaaagaatg gaagatggta 4700

 aacaatcact ttttaaaacc tgttaagtca aaaccatctt ggctaatatg 4750

 tactggggaa ataatccata agagatatca ccagactaga attaatatat 4800

 ttataaagaa agagaccaaa actgtctaga atttgaaagg gtttacatat 4850

 tattatacta aagcagtact ggactggcca ttggaccatt tgttccaaaa 4900

 cccataaatt gttgcctaaa tttataatga tcatgaaacc ctaggcagag 4950

 gaggagaaat tgaaggtcca gggcaatgaa agaaaaatgg cgccctctca 5000

 atttagtctt ctctcattgg ccatgtttca gattttgacc tagaaatgcg 5050

 agctgtggtt aggcttggtt agagtgcagc aagcaacatg acagatggtg 5100

 gcacgctgtt tttacccagc cctgcctgta catacacatg cacaccctct 5150

 ctgatatttt tgtcctttag atgttcaaat actcagtagt ccttttgttt 5200

 gcggtttaga ttcattttgt ccacacatgt acccatttta aaaaacaatg 5250

 tcctcgatgc ttctgtagtg atttcatttt agccaggtat ttctttcttg 5300

 tgtgtgatga accagtatgg atttgctttt ctaagcctcc tgttggttac 5350

 taatctcact tggcacatta taactaaagg aatcccctca attcaaaagc 5400

 atagatggat acaaatgtca gaccgtgggt ttaatttgtt tagaacacat 5450

 ggcatttctt cacaaggtaa cctgctgtat ttatttattt tcttttggtt 5500

 aaatataatt tccaaacttt gtggtcaggc agcgtctaag gttacgttac 5550

 cacagactga cagttggtat atgtaccagc caatcccttc attaaatgta 5600

 tacagattta gttaagtagc attaaatagg attcttagaa gtatgtcctc 5650

 atagaacttt taatacttaa ggctttgtaa aaactatcca tgaagggaaa 5700

 gctcctcagc ataactgctc agggaaatag ggctaaataa ctgaacatta 5750

 aataattggt taaaggtgct gttagtcgag cctcaatgct tgctacaagg 5800

 atgtatgtac aaggactgac tttaataatt tgcattatat tgtcccaacc 5850

 agtagtttat tttttgccac ggagatgtag aagatattac aagctactgg 5900

 atgcactgtc agattaactt atttcattaa agaagttggg agaacaaata 5950

 ggaaaaaaaa aacttatttt tctagtaaat attaatgtat tacatttcaa 6000

 ataatggtgc ctgacatatt gaataattat tttctacagt gtacgtatgc 6050

 aacaaagata ttccatcatg cattagagtc agttctggct ctgcctagct 6100

 gtttacattt gcaaatgtag caaacaaggt aatgaagcaa ctatttctat 6150

 tgcagtagat atccttttgt gtgtgtgtgt gtgcattaaa gttgtaaacg 6200

 gtaacatgaa acaaatgaaa gttcttgcta taatggtatg gaaaacaaga 6250

 aggaaatgaa aatattttta tgcctactta ggaaaaaaag ggtagcactt 6300

 attcattcca agtacttttt tttttttaat ttttaagctc ttaactcaca 6350

 ttgttatgct taagatgata aacatatatc ctctttttat tgctttgtct 6400

 atgtttcata tgaaacattt cagaaattat tttgataagt gttgctggaa 6450

 tctgcaacgc tgattttttt ttgcattctg tagtcgcatt tgcactccat 6500

 ttttacatta attcgcagtt gctttgtatc attgttttgt ttgggttttg 6550

 tttctttttc acagtgccgg gtcttcgttt cttaaagttg gatggcaggt 6600

 agagttcaac cagttcgtga ctgttgtagc gaatgaagtt aaaaaaatgt 6650

 ctttctgatg ttgtgttgtc attttcattt ttgcattttt ttgtttgcat 6700

 attaaaaaaa gagaaaagag aaagcaagag acagaaatca ggactaagtc 6750

 ctctgcttca gtttcattgt taacgggcct tattctgatc tcacctgtcg 6800

 cgtagctcta atattcacat aaactgaaat aaagaagtgg aatgaggagc 6850

 tttgacattc aaattatgtg atgtaattta tcttccttag gaattttgat 6900

 ggatgcatct caaaatgtat agccagactt gagaggtgac aattaaagat 6950

 ctaaaaaaga gaggagattc ccccaaacaa caatatttaa ttttcttagt 7000

 aaaaagaata acagaatgca tcgtggcaat ccttaagcaa cattatctat 7050

 gtggactgct taaatcagca aaacaccaga agtttggtta acttgggcaa 7100

 tatgacaagt attacttttt gggcaaaact actcattaag caatttctct 7150

 agtgtgtcgg acacaaatag gttctttatt tttggcatgt atgccttttt 7200

 attttcattc aatttttttt ttttctcaga cagacatagt agtatcaact 7250

 agcattggaa aatacatatc actattcttg gaatatttat ggtcagtcta 7300

 ctttttagta aaatattttt ggatagcgtt gacacgatag atcttattcc 7350

 atacttcttt attattgata attttatttt cattttttgc tttcattatt 7400

 atacatattt tggtggagaa gaggttgggc ttttttgaaa gagacaaaaa 7450

 tttattataa cactaaacac tccttttttg acatattaaa gcctttattc 7500

 catctctcaa gatatattat aaaatttatt tttttaattt aagatttctg 7550

 aattatttta tcttaaattg tgattttaaa cgagctatta tggtacggaa 7600

 ctttttttaa tgaggaattt catgatgatt taggaatttt ctctcttgga 7650

 aaaggcttcc cctgtgatga aaatgatgtg ccagctaaaa ttgtgtgcca 7700

 tttaaaaact gaaaatattt taaaattatt tgtctatatt ctaaattgag 7750

 ctttggatca aactttaggc caggaccagc tcatgcgttc tcattcttcc 7800

 ttttctcact ctttctctca tcactcacct ctgtattcat tctgttgttt 7850

 gggatagaaa aatcataaag agccaaccca tctcagaacg ttgtggattg 7900

 agagagacac tacatgactc caagtatatg agaaaaggac agagctctaa 7950

 ttgataactc tgtagttcaa aaggaaaaga gtatgcccaa ttctctctac 8000

 atgacatatt gagatttttt ttaatcaact tttaagatag tgatgttctg 8050

 ttctaaactg ttctgtttta gtgaaggtag atttttataa aacaagcatg 8100

 gggattcttt tctaaggtaa tattaatgag aagggaaaaa agtatcttta 8150

 acagctcttt gttgaagcct gtggtagcac attatgttta taattgcaca 8200

 tgtgcacata atctattatg atccaatgca aatacagctc caaaaatatt 8250

 aaatgtatat atattttaaa atgcctgagg aaatacattt ttcttaataa 8300

 actgaagagt ctcagtatgg ctattaaaat aattattagc ctcctgttgt 8350

 gtggctgcaa aacatcacaa agtgaccggt cttgagacct gtgaactgct 8400

 gccctgttta gtaaataaaa ttaatgcatt tctagagggg gaatatctgc 8450

 catccagtgg tggaaatgtg gagtaaagaa gctggtggtc tgcttctgtg 8500

 ctgtatgcca gccttttgcc ttaagttgag aggaggtcaa ctttagctac 8550

 tgtctttggt ttgagagcca tggcaaaaaa aaaaaaagaa aaaaagatca 8600

 agtcgtcttt ggtgagccag taaggtgaaa gcttgctgac tgtccaaggc 8650

 acaagagaaa attgaggaat tgaaatgcaa cctgagtatc aaactaaata 8700

 ttctaatcaa aggtaggtac tgttaggtgg aattctatca gcaggcaact 8750

 gcaaatgaga agaagataga aggacgcccg tcgggacttt ggagggcatt 8800

 gttattttcc caaagaaaga cggccaaggg cagaggcatg gattctttgc 8850

 agagcacttc cttttggttt ttcagtactg tttcatagac agtgggctca 8900

 catgttcctg atagtgctgc agttgcttag aaagcatccc agttaattgc 8950

 agtaattaga acttctggaa tatgctaggg cagaagtatg tcaagtatgt 9000

 cacatgaaga aaatgtgaaa ttcaagagta atccacacgt gagaaactag 9050

 acaatgtaca ttcatgtgtt ctcttgaaag gaaagggaga gctgtaagct 9100

 tcactctgtc ctacaccgga gaaaagcagg aataacttta ccgtggaaat 9150

 aatgtttagc ttttatcaga gaaaattgtc cttctagagc atagagtccc 9200

 aaaactcaat tctggttttc ccctgttttt tttttttttt tttttcccaa 9250

 catatgaact gcagcatatc actttttctt tttgtgcctc aggttcctca 9300

 cctgtaaaat tgaaaaatat atgtattaat aatattatta ataataataa 9350

 tggtaatgta gtacttgttt gtaaagcact ttgagatcct tggttgaaag 9400

 gcaccatagg agtgccaagt attattatgt ggccaagggg gttatttaaa 9450

 ctgtcagttc ccaaaggcca ggaaaggttg gggtcatttt tcttaaagac 9500

 gagctgtaaa tatcaactag gcagccaata gtgttgacta tgaagatgca 9550

 aaactattac taggctgata aaatcatagt ttcttaatgg ctaccaataa 9600

 ggcaaatatc acaataataa acgccaaatt ccttagggcg gactatttga 9650

 caaccacatg gaaaactttg ggggaggcat gaggggggaa catctcaaaa 9700

 tgccaatgta aaatttaact tacagcaata ttcaccagca gaaaatgtct 9750

 ttcatatgga atgatttcat gttgctaaga aaaagaattc aatttgtagt 9800

 cctgatttga atactagaat gttggctata atagttctgt tcttacaaca 9850

 catgaaattt tttcgtttta ttttattttg ttttcatagt gcatgttcat 9900

 ttctactcac aaacatgttc ttggtgtatt tcttatgcaa acaatcttca 9950

 ggcagcaaag atgtctgtta catctaaact tgaataataa agttttacca 10000

 ccagttacac a 10011

<210> 3982
<211> 1281
<212> PRT
<213> Homo sapien

<400> 3982
 Met Val Arg Lys Lys Asn Pro Pro Leu Arg Asn Val Ala Ser Glu
   1               5                  10                  15

 Gly Glu Gly Gln Ile Leu Glu Pro Ile Gly Thr Glu Ser Lys Val
                  20                  25                  30

 Ser Gly Lys Asn Lys Glu Phe Ser Ala Asp Gln Met Ser Glu Asn
                  35                  40                  45

 Thr Asp Gln Ser Asp Ala Ala Glu Leu Asn His Lys Glu Glu His
                  50                  55                  60

 Ser Leu His Val Gln Asp Pro Ser Ser Ser Ser Lys Lys Asp Leu
                  65                  70                  75

 Lys Ser Ala Val Leu Ser Glu Lys Ala Gly Phe Asn Tyr Glu Ser
                  80                  85                  90

 Pro Ser Lys Gly Gly Asn Phe Pro Ser Phe Pro His Asp Glu Val
                  95                 100                 105

 Thr Asp Arg Asn Met Leu Ala Phe Ser Phe Pro Ala Ala Gly Gly
                 110                 115                 120

 Val Cys Glu Pro Leu Lys Ser Pro Gln Arg Ala Glu Ala Asp Asp
                 125                 130                 135

 Pro Gln Asp Met Ala Cys Thr Pro Ser Gly Asp Ser Leu Glu Thr
                 140                 145                 150

 Lys Glu Asp Gln Lys Met Ser Pro Lys Ala Thr Glu Glu Thr Gly
                 155                 160                 165

 Gln Ala Gln Ser Gly Gln Ala Asn Cys Gln Gly Leu Ser Pro Val
                 170                 175                 180

 Ser Val Ala Ser Lys Asn Pro Gln Val Pro Ser Asp Gly Gly Val
                 185                 190                 195

 Arg Leu Asn Lys Ser Lys Thr Asp Leu Leu Val Asn Asp Asn Pro
                 200                 205                 210

 Asp Pro Ala Pro Leu Ser Pro Glu Leu Gln Asp Phe Lys Cys Asn
                 215                 220                 225

 Ile Cys Gly Tyr Gly Tyr Tyr Gly Asn Asp Pro Thr Asp Leu Ile
                 230                 235                 240

 Lys His Phe Arg Lys Tyr His Leu Gly Leu His Asn Arg Thr Arg
                 245                 250                 255

 Gln Asp Ala Glu Leu Asp Ser Lys Ile Leu Ala Leu His Asn Met
                 260                 265                 270

 Val Gln Phe Ser His Ser Lys Asp Phe Gln Lys Val Asn Arg Ser
                 275                 280                 285

 Val Phe Ser Gly Val Leu Gln Asp Ile Asn Ser Ser Arg Pro Val
                 290                 295                 300

 Leu Leu Asn Gly Thr Tyr Asp Val Gln Val Thr Ser Gly Gly Thr
                 305                 310                 315

 Phe Ile Gly Ile Gly Arg Lys Thr Pro Asp Cys Gln Gly Asn Thr
                 320                 325                 330

 Lys Tyr Phe Arg Cys Lys Phe Cys Asn Phe Thr Tyr Met Gly Asn
                 335                 340                 345

 Ser Ser Thr Glu Leu Glu Gln His Phe Leu Gln Thr His Pro Asn
                 350                 355                 360

 Lys Ile Lys Ala Ser Leu Pro Ser Ser Glu Val Ala Lys Pro Ser
                 365                 370                 375

 Glu Lys Asn Ser Asn Lys Ser Ile Pro Ala Leu Gln Ser Ser Asp
                 380                 385                 390

 Ser Gly Asp Leu Gly Lys Trp Gln Asp Lys Ile Thr Val Lys Ala
                 395                 400                 405

 Gly Asp Asp Thr Pro Val Gly Tyr Ser Val Pro Ile Lys Pro Leu
                 410                 415                 420

 Asp Ser Ser Arg Gln Asn Gly Thr Glu Ala Thr Ser Tyr Tyr Trp
                 425                 430                 435

 Cys Lys Phe Cys Ser Phe Ser Cys Glu Ser Ser Ser Ser Leu Lys
                 440                 445                 450

 Leu Leu Glu His Tyr Gly Lys Gln His Gly Ala Val Gln Ser Gly
                 455                 460                 465

 Gly Leu Asn Pro Glu Leu Asn Asp Lys Leu Ser Arg Gly Ser Val
                 470                 475                 480

 Ile Asn Gln Asn Asp Leu Ala Lys Ser Ser Glu Gly Glu Thr Met
                 485                 490                 495

 Thr Lys Thr Asp Lys Ser Ser Ser Gly Ala Lys Lys Lys Asp Phe
                 500                 505                 510

 Ser Ser Lys Gly Ala Glu Asp Asn Met Val Thr Ser Tyr Asn Cys
                 515                 520                 525

 Gln Phe Cys Asp Phe Arg Tyr Ser Lys Ser His Gly Pro Asp Val
                 530                 535                 540

 Ile Val Val Gly Pro Leu Leu Arg His Tyr Gln Gln Leu His Asn
                 545                 550                 555

 Ile His Lys Cys Thr Ile Lys His Cys Pro Phe Cys Pro Arg Gly
                 560                 565                 570

 Leu Cys Ser Pro Glu Lys His Leu Gly Glu Ile Thr Tyr Pro Phe
                 575                 580                 585

 Ala Cys Arg Lys Ser Asn Cys Ser His Cys Ala Leu Leu Leu Leu
                 590                 595                 600

 His Leu Ser Pro Gly Ala Ala Gly Ser Ser Arg Val Lys His Gln
                 605                 610                 615

 Cys His Gln Cys Ser Phe Thr Thr Pro Asp Val Asp Val Leu Leu
                 620                 625                 630

 Phe His Tyr Glu Ser Val His Glu Ser Gln Ala Ser Asp Val Lys
                 635                 640                 645

 Gln Glu Ala Asn His Leu Gln Gly Ser Asp Gly Gln Gln Ser Val
                 650                 655                 660

 Lys Glu Ser Lys Glu His Ser Cys Thr Lys Cys Asp Phe Ile Thr
                 665                 670                 675

 Gln Val Glu Glu Glu Ile Ser Arg His Tyr Arg Arg Ala His Ser
                 680                 685                 690

 Cys Tyr Lys Cys Arg Gln Cys Ser Phe Thr Ala Ala Asp Thr Gln
                 695                 700                 705

 Ser Leu Leu Glu His Phe Asn Thr Val His Cys Gln Glu Gln Asp
                 710                 715                 720

 Ile Thr Thr Ala Asn Gly Glu Glu Asp Gly His Ala Ile Ser Thr
                 725                 730                 735

 Ile Lys Glu Glu Pro Lys Ile Asp Phe Arg Val Tyr Asn Leu Leu
                 740                 745                 750

 Thr Pro Asp Ser Lys Met Gly Glu Pro Val Ser Glu Ser Val Val
                 755                 760                 765

 Lys Arg Glu Lys Leu Glu Glu Lys Asp Gly Leu Lys Glu Lys Val
                 770                 775                 780

 Trp Thr Glu Ser Ser Ser Asp Asp Leu Arg Asn Val Thr Trp Arg
                 785                 790                 795

 Gly Ala Asp Ile Leu Arg Gly Ser Pro Ser Tyr Thr Gln Ala Ser
                 800                 805                 810

 Leu Gly Leu Leu Thr Pro Val Ser Gly Thr Gln Glu Gln Thr Lys
                 815                 820                 825

 Thr Leu Arg Asp Ser Pro Asn Val Glu Ala Ala His Leu Ala Arg
                 830                 835                 840

 Pro Ile Tyr Gly Leu Ala Val Glu Thr Lys Gly Phe Leu Gln Gly
                 845                 850                 855

 Ala Pro Ala Gly Gly Glu Lys Ser Gly Ala Leu Pro Gln Gln Tyr
                 860                 865                 870

 Pro Ala Ser Gly Glu Asn Lys Ser Lys Asp Glu Ser Gln Ser Leu
                 875                 880                 885

 Leu Arg Arg Arg Arg Gly Ser Gly Val Phe Cys Ala Asn Cys Leu
                 890                 895                 900

 Thr Thr Lys Thr Ser Leu Trp Arg Lys Asn Ala Asn Gly Gly Tyr
                 905                 910                 915

 Val Cys Asn Ala Cys Gly Leu Tyr Gln Lys Leu His Ser Thr Pro
                 920                 925                 930

 Arg Pro Leu Asn Ile Ile Lys Gln Asn Asn Gly Glu Gln Ile Ile
                 935                 940                 945

 Arg Arg Arg Thr Arg Lys Arg Leu Asn Pro Glu Ala Leu Gln Ala
                 950                 955                 960

 Glu Gln Leu Asn Lys Gln Gln Arg Gly Ser Asn Glu Glu Gln Val
                 965                 970                 975

 Asn Gly Ser Pro Leu Glu Arg Arg Ser Glu Asp His Leu Thr Glu
                 980                 985                 990

 Ser His Gln Arg Glu Ile Pro Leu Pro Ser Leu Ser Lys Tyr Glu
                 995                1000                1005

 Ala Gln Gly Ser Leu Thr Lys Ser His Ser Ala Gln Gln Pro Val
                1010                1015                1020

 Leu Val Ser Gln Thr Leu Asp Ile His Lys Arg Met Gln Pro Leu
                1025                1030                1035

 His Ile Gln Ile Lys Ser Pro Gln Glu Ser Thr Gly Asp Pro Gly
                1040                1045                1050

 Asn Ser Ser Ser Val Ser Glu Gly Lys Gly Ser Ser Glu Arg Gly
                1055                1060                1065

 Ser Pro Ile Glu Lys Tyr Met Arg Pro Ala Lys His Pro Asn Tyr
                1070                1075                1080

 Ser Pro Pro Gly Ser Pro Ile Glu Lys Tyr Gln Tyr Pro Leu Phe
                1085                1090                1095

 Gly Leu Pro Phe Val His Asn Asp Phe Gln Ser Glu Ala Asp Trp
                1100                1105                1110

 Leu Arg Phe Trp Ser Lys Tyr Lys Leu Ser Val Pro Gly Asn Pro
                1115                1120                1125

 His Tyr Leu Ser His Val Pro Gly Leu Pro Asn Pro Cys Gln Asn
                1130                1135                1140

 Tyr Val Pro Tyr Pro Thr Phe Asn Leu Pro Pro His Phe Ser Ala
                1145                1150                1155

 Val Gly Ser Asp Asn Asp Ile Pro Leu Asp Leu Ala Ile Lys His
                1160                1165                1170

 Ser Arg Pro Gly Pro Thr Ala Asn Gly Ala Ser Lys Glu Lys Thr
                1175                1180                1185

 Lys Ala Pro Pro Asn Val Lys Asn Glu Gly Pro Leu Asn Val Val
                1190                1195                1200

 Lys Thr Glu Lys Val Asp Arg Ser Thr Gln Asp Glu Leu Ser Thr
                1205                1210                1215

 Lys Cys Val His Cys Gly Ile Val Phe Leu Asp Glu Val Met Tyr
                1220                1225                1230

 Ala Leu His Met Ser Cys His Gly Asp Ser Gly Pro Phe Gln Cys
                1235                1240                1245

 Ser Ile Cys Gln His Leu Cys Thr Asp Lys Tyr Asp Phe Thr Thr
                1250                1255                1260

 His Ile Gln Arg Gly Leu His Arg Asn Asn Ala Gln Val Glu Lys
                1265                1270                1275

 Asn Gly Lys Pro Lys Glu
                1280

<210> 3983
<211> 1217
<212> DNA
<213> Homo sapien

<400> 3983
 caactcatgg cggcggcggc ggcggcggca gctgcttggg cgcggtgcgg 50

 tggtgactga gctacgagcc tggcggcggg tgtgcgccga gccccggccc 100

 ggcccggccc tcgcgtgcct cccaggctcc gcacccctga tgctgcgcgg 150

 gtgctgagcc cgcttcggcc gggacgatgg tgaagtattt cctgggccag 200

 agcgtgctcc ggagttcctg ggaccaagtg ttcgccgcct tctggcagcg 250

 gtacccgaat ccctatagca aacatgtctt gacggaagac atagtacacc 300

 gggaggtgac ccctgaccag aaactgctgt cccggcgact cctgaccaag 350

 accaacagga tgccacgctg ggccgagcga ctatttcctg ccaatgttgc 400

 tcactcggtg tacgtcctgg aggactctat tgtggaccca cagaatcaga 450

 ccatgactac cttcacctgg aacatcaacc acgcccggct gatggtggtg 500

 gaggaacgat gtgtttactg tgtgaactct gacaacagtg gctggactga 550

 aatccgccgg gaagcctggg tctcctctag cttatttggt gtctccagag 600

 ctgtccagga atttggtctt gcccggttca aaagcaacgt gaccaagact 650

 atgaagggtt ttgaatatat cttggctaag ctgcaaggcg aggccccttc 700

 caaaacactt gttgagacag ccaaggaagc caaggagaag gcaaaggaga 750

 cggcactggc agctacagag aaggccaagg acctcgccag caaggcggcc 800

 accaagaagc agcagcagca gcaacagttt gtgtagccag tctaccacca 850

 ccacagcacc ccagacagct aggcttagcc cctctgccct cccttcattg 900

 tactttatca ttaaaaatca acttccagcc ctgtctgctg tctacgtggt 950

 gggttgtggg gatgcagttt ggcatctgca gtacaccaag cacatgattc 1000

 atgtctgagc caggtctgct tattctccca ttgggcagct gaggaccgag 1050

 gcacagaggt gcggtgactt gcccggggct ccaggtagcc tgcaggttaa 1100

 ctggcggtaa gtgctagact gtaagcccga caagggcagg gcttttggtt 1150

 ttgttctctg atgtgtctca gtatctagca cataatagac actcaataaa 1200

 tacttgttga attcaaa 1217

<210> 3984
<211> 219
<212> PRT
<213> Homo sapien

<400> 3984
 Met Val Lys Tyr Phe Leu Gly Gln Ser Val Leu Arg Ser Ser Trp
   1               5                  10                  15

 Asp Gln Val Phe Ala Ala Phe Trp Gln Arg Tyr Pro Asn Pro Tyr
                  20                  25                  30

 Ser Lys His Val Leu Thr Glu Asp Ile Val His Arg Glu Val Thr
                  35                  40                  45

 Pro Asp Gln Lys Leu Leu Ser Arg Arg Leu Leu Thr Lys Thr Asn
                  50                  55                  60

 Arg Met Pro Arg Trp Ala Glu Arg Leu Phe Pro Ala Asn Val Ala
                  65                  70                  75

 His Ser Val Tyr Val Leu Glu Asp Ser Ile Val Asp Pro Gln Asn
                  80                  85                  90

 Gln Thr Met Thr Thr Phe Thr Trp Asn Ile Asn His Ala Arg Leu
                  95                 100                 105

 Met Val Val Glu Glu Arg Cys Val Tyr Cys Val Asn Ser Asp Asn
                 110                 115                 120

 Ser Gly Trp Thr Glu Ile Arg Arg Glu Ala Trp Val Ser Ser Ser
                 125                 130                 135

 Leu Phe Gly Val Ser Arg Ala Val Gln Glu Phe Gly Leu Ala Arg
                 140                 145                 150

 Phe Lys Ser Asn Val Thr Lys Thr Met Lys Gly Phe Glu Tyr Ile
                 155                 160                 165

 Leu Ala Lys Leu Gln Gly Glu Ala Pro Ser Lys Thr Leu Val Glu
                 170                 175                 180

 Thr Ala Lys Glu Ala Lys Glu Lys Ala Lys Glu Thr Ala Leu Ala
                 185                 190                 195

 Ala Thr Glu Lys Ala Lys Asp Leu Ala Ser Lys Ala Ala Thr Lys
                 200                 205                 210

 Lys Gln Gln Gln Gln Gln Gln Phe Val
                 215

<210> 3985
<211> 2112
<212> DNA
<213> Homo sapien

<400> 3985
 ggtcgggacc ggcaagatgg cggcgcggac agcgttcggt gctgtgtgcc 50

 ggcgcctctg gcagggattg gggaattttt ctgtaaacac ttctaagggc 100

 aatacagcca aaaatggtgg cttgcttctc agtaccaata tgaagtgggt 150

 acagttttca aacctacacg ttgatgttcc aaaggatttg accaaacctg 200

 tggtaacaat ctctgatgaa ccagacatat tatataagcg cctctcggtt 250

 ttggtgaaag gtcacgataa ggctgtattg gacagttatg aatattttgc 300

 tgtgcttgct gctaaagaac ttggtatctc tattaaagta catgaacctc 350

 caaggaaaat agagcgattt actcttctcc aatcagtgca tatttacaag 400

 aagcacagag ttcagtatga aatgagaaca ctttacagat gtttagagtt 450

 agaacatcta actggaagca cagcagatgt ctacttggaa tatattcagc 500

 gaaacttacc tgaaggggtt gccatggaag taacaaagac acaattagaa 550

 cagttaccag aacacatcaa ggagccaatc tgggaaacac tatcagaaga 600

 aaaagaagaa agcaagtcat aaagcctcag ggaggccatt tttgcctaaa 650

 tttgaaatga gggtgggcca gatgagtatg tttaagtgga gagtgcttcc 700

 agctgagatg atttgagtct gtcctaactg ctccattgag ttctcgtgcc 750

 ctcatcagct gagggcaggg aatggaactt taatggaaga accactttta 800

 tctattcttt ttattcattg tttcagttct gatttcagca aacatgagca 850

 aaccactttg actgaaagca gaaagagtga aaattctatt ttgttacgct 900

 actggtgttc aattattagt ttgtaccatt tttaatttat gtcagttgat 950

 gcatctgaaa ataagtgctt ggagtgttcg tacccttatt tttttttaag 1000

 attcctagaa ggaatctttg gttaattcag attgagcagt taaagttttt 1050

 gctatttacc tttgtgcagg ctggcatatg ctaatttggg ggtggtaacc 1100

 aaccgatttt atctcatgta agcattacat tttgaagact gaatatactt 1150

 cacagcagat caaacacatt tatggcatgc actgacctct tcttggagcc 1200

 cagaacttta tagagttgcc taccagggtt actgtaatgg aatttatgat 1250

 cttaagaaat tactagttgt attatttatc ctatgattca ttcattcaat 1300

 aagcttttac tgcataaact ttacatccag cactgtagtt aagtacccaa 1350

 aattgaatag aaataatggc ttttgaaaat tgcacaaagc aggccaggca 1400

 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcaggcgg 1450

 atcacgaggt caagagatcc agaccatcct ggctaacacg gtgaaacccc 1500

 gtctctaata aaaatacaaa aattagctgg acatggtggc acgtgcctgt 1550

 aatcccagct actcaggagg ctgaggcagg agaatcgcgt gaacccgggc 1600

 ccggtggagg ctgcagtgag acgagatcgc gccactgcac tccagcctgg 1650

 cgacagagcg agacaccgtc tcaaaaaaaa aaaaaaagaa aattgtgcaa 1700

 agcataggta aatatttttc tttattaagc ttctcactga gaagccctct 1750

 ttattttggt aaatgtcact ctgtttgtta ggagatgtct gcttttccat 1800

 gaaatgaaat agtggctaaa gccctgaaag aggcaagact acaatgggct 1850

 gaaacagttg gtatagcaac cccagagaag tgcttcattt tctttttata 1900

 gtagaagcag gtccatgtct tttgtggttt cctgcacatc tttggagtag 1950

 ttatgacttc tcagtttttc cccccttaaa ctgcattgcc tattcttttt 2000

 tcctgacatg ctatcaggta tcagtgtgtt gaatacataa tgcttgtgta 2050

 tcagacttac gttactgtca tcaccattaa aagaattgca gccttgtgcc 2100

 ccatgacctt ca 2112

<210> 3986
<211> 201
<212> PRT
<213> Homo sapien

<400> 3986
 Met Ala Ala Arg Thr Ala Phe Gly Ala Val Cys Arg Arg Leu Trp
   1               5                  10                  15

 Gln Gly Leu Gly Asn Phe Ser Val Asn Thr Ser Lys Gly Asn Thr
                  20                  25                  30

 Ala Lys Asn Gly Gly Leu Leu Leu Ser Thr Asn Met Lys Trp Val
                  35                  40                  45

 Gln Phe Ser Asn Leu His Val Asp Val Pro Lys Asp Leu Thr Lys
                  50                  55                  60

 Pro Val Val Thr Ile Ser Asp Glu Pro Asp Ile Leu Tyr Lys Arg
                  65                  70                  75

 Leu Ser Val Leu Val Lys Gly His Asp Lys Ala Val Leu Asp Ser
                  80                  85                  90

 Tyr Glu Tyr Phe Ala Val Leu Ala Ala Lys Glu Leu Gly Ile Ser
                  95                 100                 105

 Ile Lys Val His Glu Pro Pro Arg Lys Ile Glu Arg Phe Thr Leu
                 110                 115                 120

 Leu Gln Ser Val His Ile Tyr Lys Lys His Arg Val Gln Tyr Glu
                 125                 130                 135

 Met Arg Thr Leu Tyr Arg Cys Leu Glu Leu Glu His Leu Thr Gly
                 140                 145                 150

 Ser Thr Ala Asp Val Tyr Leu Glu Tyr Ile Gln Arg Asn Leu Pro
                 155                 160                 165

 Glu Gly Val Ala Met Glu Val Thr Lys Thr Gln Leu Glu Gln Leu
                 170                 175                 180

 Pro Glu His Ile Lys Glu Pro Ile Trp Glu Thr Leu Ser Glu Glu
                 185                 190                 195

 Lys Glu Glu Ser Lys Ser
                 200

<210> 3987
<211> 1258
<212> DNA
<213> Homo sapien

<400> 3987
 caccattagg caaagatagt ttctctagag agaatcatgc ctgctaatta 50

 cacgtgtacc aggccagatg gagacaatac agattttcga tactttattt 100

 atgcagtgac atacactgtc attcttgtgc caggtctcat agggaatata 150

 ttagccctgt gggtattcta tggttatatg aaagaaacaa aacgagctgt 200

 gatatttatg ataaacttag ccattgctga cttactacaa gttctttcct 250

 tgccactgag gatcttctac tacttgaatc atgactggcc atttgggcct 300

 ggtctctgca tgttctgttt ctacctgaag tatgtcaaca tgtatgcaag 350

 catctacttc ttggtctgca tcagtgtgcg acgattttgg tttctcatgt 400

 acccctttcg cttccatgac tgcaaacaga aatatgacct gtacatcagc 450

 attgctggct ggctgatcat ctgccttgcc tgtgtactct ttccactcct 500

 cagaaccagt gatgatacct ctggcaatag gaccaaatgc tttgtggatc 550

 ttcctaccag gaatgtcaac ctggcccagt ccgttgttat gatgaccatt 600

 ggcgagttga ttgggtttgt aactccgctt ctgattgtcc tatattgtac 650

 ctggaagacg gttttatcac tgcaagataa atatcccatg gcccaagatc 700

 ttggagagaa acagaaagcc ttgaagatga ttctaacctg tgcaggggta 750

 ttcctaattt gctttgcacc ttatcatttc agttttcctt tagatttcct 800

 ggtgaagtcc aatgaaatta aaagctgcct agccagaagg gtgattctaa 850

 tatttcattc tgtggcattg tgtcttgcta gtctgaattc atgtcttgac 900

 ccagtcatat actacttttc cactaatgag ttccgaagac ggctttcaag 950

 acaagatttg catgacagca tccaactcca tgcaaaatcc tttgtgagta 1000

 accatacagc ttccaccatg acacctgaat tatgctaaaa caaaaaacca 1050

 aactgaatgt gacctgaaat gcaagtacat cagaacatat ctgcaatacc 1100

 caagccacag ggaagaactt gcaaaacaac acagcttttc agttctgctc 1150

 tatcttactg ctatggggaa ttcacttctt caaagcagga cctatttgga 1200

 gcattacgat ccacgattat tgatgttgac atgtccatgt agtaattttt 1250

 cttcaagt 1258

<210> 3988
<211> 333
<212> PRT
<213> Homo sapien

<400> 3988
 Met Pro Ala Asn Tyr Thr Cys Thr Arg Pro Asp Gly Asp Asn Thr
   1               5                  10                  15

 Asp Phe Arg Tyr Phe Ile Tyr Ala Val Thr Tyr Thr Val Ile Leu
                  20                  25                  30

 Val Pro Gly Leu Ile Gly Asn Ile Leu Ala Leu Trp Val Phe Tyr
                  35                  40                  45

 Gly Tyr Met Lys Glu Thr Lys Arg Ala Val Ile Phe Met Ile Asn
                  50                  55                  60

 Leu Ala Ile Ala Asp Leu Leu Gln Val Leu Ser Leu Pro Leu Arg
                  65                  70                  75

 Ile Phe Tyr Tyr Leu Asn His Asp Trp Pro Phe Gly Pro Gly Leu
                  80                  85                  90

 Cys Met Phe Cys Phe Tyr Leu Lys Tyr Val Asn Met Tyr Ala Ser
                  95                 100                 105

 Ile Tyr Phe Leu Val Cys Ile Ser Val Arg Arg Phe Trp Phe Leu
                 110                 115                 120

 Met Tyr Pro Phe Arg Phe His Asp Cys Lys Gln Lys Tyr Asp Leu
                 125                 130                 135

 Tyr Ile Ser Ile Ala Gly Trp Leu Ile Ile Cys Leu Ala Cys Val
                 140                 145                 150

 Leu Phe Pro Leu Leu Arg Thr Ser Asp Asp Thr Ser Gly Asn Arg
                 155                 160                 165

 Thr Lys Cys Phe Val Asp Leu Pro Thr Arg Asn Val Asn Leu Ala
                 170                 175                 180

 Gln Ser Val Val Met Met Thr Ile Gly Glu Leu Ile Gly Phe Val
                 185                 190                 195

 Thr Pro Leu Leu Ile Val Leu Tyr Cys Thr Trp Lys Thr Val Leu
                 200                 205                 210

 Ser Leu Gln Asp Lys Tyr Pro Met Ala Gln Asp Leu Gly Glu Lys
                 215                 220                 225

 Gln Lys Ala Leu Lys Met Ile Leu Thr Cys Ala Gly Val Phe Leu
                 230                 235                 240

 Ile Cys Phe Ala Pro Tyr His Phe Ser Phe Pro Leu Asp Phe Leu
                 245                 250                 255

 Val Lys Ser Asn Glu Ile Lys Ser Cys Leu Ala Arg Arg Val Ile
                 260                 265                 270

 Leu Ile Phe His Ser Val Ala Leu Cys Leu Ala Ser Leu Asn Ser
                 275                 280                 285

 Cys Leu Asp Pro Val Ile Tyr Tyr Phe Ser Thr Asn Glu Phe Arg
                 290                 295                 300

 Arg Arg Leu Ser Arg Gln Asp Leu His Asp Ser Ile Gln Leu His
                 305                 310                 315

 Ala Lys Ser Phe Val Ser Asn His Thr Ala Ser Thr Met Thr Pro
                 320                 325                 330

 Glu Leu Cys


<210> 3989
<211> 728
<212> DNA
<213> Homo sapien

<400> 3989
 ttttcgagac cggaagtgag tgatcgaaag catggcgtcg gtggtgttgg 50

 cgctgaggac ccggacagcc gttacatcct tgctaagccc cactccggct 100

 acagctcttg ctgtcagata cgcatccaag aagtcgggtg gtagctccaa 150

 aaacctcggt ggaaagtcat caggcagacg ccaaggcatt aagaaaatgg 200

 aaggtcacta tgttcatgct gggaacatca ttgcaacaca gcgccatttc 250

 cgctggcacc caggtgccca tgtgggtgtt gggaagaata aatgtctgta 300

 tgccctggaa gaggggatag tccgctacac taaggaggtc tacgtgcctc 350

 atcccagaaa cacggaggct gtggatctga tcaccaggct gcccaagggt 400

 gctgtgctct acaagacttt tgtccacgtg gttcctgcca agcctgaggg 450

 caccttcaaa ctggtagcta tgctttgatg tcctgttgag gccatcggac 500

 agagactgga gcccaggtga caggagatgg tgataccaga agtcaagggt 550

 tggggtggcg acacggcctc ccgaggaaga ggtctgcttg atggtgactc 600

 tgcaggagac tctgaagtga ctgctgggaa accctttggg agacctgacc 650

 tggggccaaa aataaagtga gccagcgtca tgaacgcatg ctatttaggg 700

 acaaaaaaaa aaaaaaaaaa aaaaaaaa 728

<210> 3990
<211> 148
<212> PRT
<213> Homo sapien

<400> 3990
 Met Ala Ser Val Val Leu Ala Leu Arg Thr Arg Thr Ala Val Thr
   1               5                  10                  15

 Ser Leu Leu Ser Pro Thr Pro Ala Thr Ala Leu Ala Val Arg Tyr
                  20                  25                  30

 Ala Ser Lys Lys Ser Gly Gly Ser Ser Lys Asn Leu Gly Gly Lys
                  35                  40                  45

 Ser Ser Gly Arg Arg Gln Gly Ile Lys Lys Met Glu Gly His Tyr
                  50                  55                  60

 Val His Ala Gly Asn Ile Ile Ala Thr Gln Arg His Phe Arg Trp
                  65                  70                  75

 His Pro Gly Ala His Val Gly Val Gly Lys Asn Lys Cys Leu Tyr
                  80                  85                  90

 Ala Leu Glu Glu Gly Ile Val Arg Tyr Thr Lys Glu Val Tyr Val
                  95                 100                 105

 Pro His Pro Arg Asn Thr Glu Ala Val Asp Leu Ile Thr Arg Leu
                 110                 115                 120

 Pro Lys Gly Ala Val Leu Tyr Lys Thr Phe Val His Val Val Pro
                 125                 130                 135

 Ala Lys Pro Glu Gly Thr Phe Lys Leu Val Ala Met Leu
                 140                 145

<210> 3991
<211> 604
<212> DNA
<213> Homo sapien

<400> 3991
 gcagacgcag gggtcggcgc cgggtgagag cgtgcggccg gattcaccac 50

 aacatggcaa atctttttat aaggaaaatg gtgaaccctc tgctctatct 100

 cagtcgtcac acggtgaagc ctcgagccct ctccacattt ctatttggat 150

 ccattcgagg tgcagccccc gtggctgtgg aacccggggc agcagtgcgc 200

 tcacttctct cacccggcct cctgccccat ctgctgcctg cgctggggtt 250

 caaaaacaag actgtcctta agaagcgctg caaggactgt tacctggtga 300

 agaggcgggg tcggtggtac gtctactgta aaacccatcc gaggcacaag 350

 cagagacaga tgtagaccct ttccctccag agtcacgcac atactcgtca 400

 tcgcatcact tgggagaatg gttgtatctt atggaaggaa ttatcacatc 450

 aaggagtcag gggaaagtga ctggaagcaa acgccctaaa agttacccat 500

 cacgtttcag tgtaaatgag taactataga agacattgcg ttatcttatt 550

 tccaaaacgt tccaactaaa aaacattttc ctattaaaat agaccttccg 600

 aata 604

<210> 3992
<211> 103
<212> PRT
<213> Homo sapien

<400> 3992
 Met Ala Asn Leu Phe Ile Arg Lys Met Val Asn Pro Leu Leu Tyr
   1               5                  10                  15

 Leu Ser Arg His Thr Val Lys Pro Arg Ala Leu Ser Thr Phe Leu
                  20                  25                  30

 Phe Gly Ser Ile Arg Gly Ala Ala Pro Val Ala Val Glu Pro Gly
                  35                  40                  45

 Ala Ala Val Arg Ser Leu Leu Ser Pro Gly Leu Leu Pro His Leu
                  50                  55                  60

 Leu Pro Ala Leu Gly Phe Lys Asn Lys Thr Val Leu Lys Lys Arg
                  65                  70                  75

 Cys Lys Asp Cys Tyr Leu Val Lys Arg Arg Gly Arg Trp Tyr Val
                  80                  85                  90

 Tyr Cys Lys Thr His Pro Arg His Lys Gln Arg Gln Met
                  95                 100

<210> 3993
<211> 745
<212> DNA
<213> Homo sapien

<400> 3993
 ggggactcca acgctgggtg acattgagct caccagcgcc accgtccccg 50

 gcgaagttct gcgctggtcg gcggagtagc aagtggccat ggggagcctc 100

 agcggtctgc gcctggcagc aggaagctgt tttaggttat gtgaaagaga 150

 tgtttcctca tctctaaggc ttaccagaag ctctgatttg aagagaataa 200

 atggattttg cacaaaacca caggaaagtc ccggagttcc atcccgcact 250

 tacaacagag tgcctttaca caaacctacg gattggcaga aaaagatcct 300

 catatggtca ggtcgcttca aaaaggaaga tgaaatccca gagactgtct 350

 cgttggagat gcttgatgct gcaaagaaca agatgcgagt gaagatcagc 400

 tatctaatga ttgccctgac ggtggtagga tgcatcttca tggttattga 450

 gggcaagaag gctgcccaaa gacacgagac tttaacaagc ttgaacttag 500

 aaaagaaagc tcgtctgaaa gaggaagcag ctatgaaggc caaaacagag 550

 tagcagaggt atccgtgttg gctggatttt gaaaatccag gaattatgtt 600

 ataacgtgcc tgtattaaaa aggatgtggt atgaggatcc atttcataaa 650

 gtatgatttg cccaaacctg taccatttcc gtatttctgc tgtagaagta 700

 gaaataaatt ttccaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 745

<210> 3994
<211> 154
<212> PRT
<213> Homo sapien

<400> 3994
 Met Gly Ser Leu Ser Gly Leu Arg Leu Ala Ala Gly Ser Cys Phe
   1               5                  10                  15

 Arg Leu Cys Glu Arg Asp Val Ser Ser Ser Leu Arg Leu Thr Arg
                  20                  25                  30

 Ser Ser Asp Leu Lys Arg Ile Asn Gly Phe Cys Thr Lys Pro Gln
                  35                  40                  45

 Glu Ser Pro Gly Val Pro Ser Arg Thr Tyr Asn Arg Val Pro Leu
                  50                  55                  60

 His Lys Pro Thr Asp Trp Gln Lys Lys Ile Leu Ile Trp Ser Gly
                  65                  70                  75

 Arg Phe Lys Lys Glu Asp Glu Ile Pro Glu Thr Val Ser Leu Glu
                  80                  85                  90

 Met Leu Asp Ala Ala Lys Asn Lys Met Arg Val Lys Ile Ser Tyr
                  95                 100                 105

 Leu Met Ile Ala Leu Thr Val Val Gly Cys Ile Phe Met Val Ile
                 110                 115                 120

 Glu Gly Lys Lys Ala Ala Gln Arg His Glu Thr Leu Thr Ser Leu
                 125                 130                 135

 Asn Leu Glu Lys Lys Ala Arg Leu Lys Glu Glu Ala Ala Met Lys
                 140                 145                 150

 Ala Lys Thr Glu


<210> 3995
<211> 2077
<212> DNA
<213> Homo sapien

<400> 3995
 agcgcagcgt gcgggtggcc tggatcccgc gcagtggccc ggcgatgtcg 50

 ctcgtgctgc taagcctggc cgcgctgtgc aggagcgccg taccccgaga 100

 gccgaccgtt caatgtggct ctgaaactgg gccatctcca gagtggatgc 150

 tacaacatga tctaatcccc ggagacttga gggacctccg agtagaacct 200

 gttacaacta gtgttgcaac aggggactat tcaattttga tgaatgtaag 250

 ctgggtactc cgggcagatg ccagcatccg cttgttgaag gccaccaaga 300

 tttgtgtgac gggcaaaagc aacttccagt cctacagctg tgtgaggtgc 350

 aattacacag aggccttcca gactcagacc agaccctctg gtggtaaatg 400

 gacattttcc tacatcggct tccctgtaga gctgaacaca gtctatttca 450

 ttggggccca taatattcct aatgcaaata tgaatgaaga tggcccttcc 500

 atgtctgtga atttcacctc accaggctgc ctagaccaca taatgaaata 550

 taaaaaaaag tgtgtcaagg ccggaagcct gtgggatccg aacatcactg 600

 cttgtaagaa gaatgaggag acagtagaag tgaacttcac aaccactccc 650

 ctgggaaaca gatacatggc tcttatccaa cacagcacta tcatcgggtt 700

 ttctcaggtg tttgagccac accagaagaa acaaacgcga gcttcagtgg 750

 tgattccagt gactggggat agtgaaggtg ctacggtgca gctgactcca 800

 tattttccta cttgtggcag cgactgcatc cgacataaag gaacagttgt 850

 gctctgccca caaacaggcg tccctttccc tctggataac aacaaaagca 900

 agccgggagg ctggctgcct ctcctcctgc tgtctctgct ggtggccaca 950

 tgggtgctgg tggcagggat ctatctaatg tggaggcacg aaaggatcaa 1000

 gaagacttcc ttttctacca ccacactact gccccccatt aaggttcttg 1050

 tggtttaccc atctgaaata tgtttccatc acacaatttg ttacttcact 1100

 gaatttcttc aaaaccattg cagaagtgag gtcatccttg aaaagtggca 1150

 gaaaaagaaa atagcagaga tgggtccagt gcagtggctt gccactcaaa 1200

 agaaggcagc agacaaagtc gtcttccttc tttccaatga cgtcaacagt 1250

 gtgtgcgatg gtacctgtgg caagagcgag ggcagtccca gtgagaactc 1300

 tcaagacctc ttcccccttg cctttaacct tttctgcagt gatctaagaa 1350

 gccagattca tctgcacaaa tacgtggtgg tctactttag agagattgat 1400

 acaaaagacg attacaatgc tctcagtgtc tgccccaagt accacctcat 1450

 gaaggatgcc actgctttct gtgcagaact tctccatgtc aagcagcagg 1500

 tgtcagcagg aaaaagatca caagcctgcc acgatggctg ctgctccttg 1550

 tagcccaccc atgagaagca agagacctta aaggcttcct atcccaccaa 1600

 ttacagggaa aaaacgtgtg atgatcctga agcttactat gcagcctaca 1650

 aacagcctta gtaattaaaa cattttatac caataaaatt ttcaaatatt 1700

 gctaactaat gtagcattaa ctaacgattg gaaactacat ttacaacttc 1750

 aaagctgttt tatacataga aatcaattac agttttaatt gaaaactata 1800

 accattttga taatgcaaca ataaagcatc ttcagccaaa catctagtct 1850

 tccatagacc atgcattgca gtgtacccag aactgtttag ctaatattct 1900

 atgtttaatt aatgaatact aactctaaga acccctcact gattcactca 1950

 atagcatctt aagtgaaaaa ccttctatta catgcaaaaa atcattgttt 2000

 ttaagataac aaaagtaggg aataaacaag ctgaacccac ttttaaaaaa 2050

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 2077

<210> 3996
<211> 502
<212> PRT
<213> Homo sapien

<400> 3996
 Met Ser Leu Val Leu Leu Ser Leu Ala Ala Leu Cys Arg Ser Ala
   1               5                  10                  15

 Val Pro Arg Glu Pro Thr Val Gln Cys Gly Ser Glu Thr Gly Pro
                  20                  25                  30

 Ser Pro Glu Trp Met Leu Gln His Asp Leu Ile Pro Gly Asp Leu
                  35                  40                  45

 Arg Asp Leu Arg Val Glu Pro Val Thr Thr Ser Val Ala Thr Gly
                  50                  55                  60

 Asp Tyr Ser Ile Leu Met Asn Val Ser Trp Val Leu Arg Ala Asp
                  65                  70                  75

 Ala Ser Ile Arg Leu Leu Lys Ala Thr Lys Ile Cys Val Thr Gly
                  80                  85                  90

 Lys Ser Asn Phe Gln Ser Tyr Ser Cys Val Arg Cys Asn Tyr Thr
                  95                 100                 105

 Glu Ala Phe Gln Thr Gln Thr Arg Pro Ser Gly Gly Lys Trp Thr
                 110                 115                 120

 Phe Ser Tyr Ile Gly Phe Pro Val Glu Leu Asn Thr Val Tyr Phe
                 125                 130                 135

 Ile Gly Ala His Asn Ile Pro Asn Ala Asn Met Asn Glu Asp Gly
                 140                 145                 150

 Pro Ser Met Ser Val Asn Phe Thr Ser Pro Gly Cys Leu Asp His
                 155                 160                 165

 Ile Met Lys Tyr Lys Lys Lys Cys Val Lys Ala Gly Ser Leu Trp
                 170                 175                 180

 Asp Pro Asn Ile Thr Ala Cys Lys Lys Asn Glu Glu Thr Val Glu
                 185                 190                 195

 Val Asn Phe Thr Thr Thr Pro Leu Gly Asn Arg Tyr Met Ala Leu
                 200                 205                 210

 Ile Gln His Ser Thr Ile Ile Gly Phe Ser Gln Val Phe Glu Pro
                 215                 220                 225

 His Gln Lys Lys Gln Thr Arg Ala Ser Val Val Ile Pro Val Thr
                 230                 235                 240

 Gly Asp Ser Glu Gly Ala Thr Val Gln Leu Thr Pro Tyr Phe Pro
                 245                 250                 255

 Thr Cys Gly Ser Asp Cys Ile Arg His Lys Gly Thr Val Val Leu
                 260                 265                 270

 Cys Pro Gln Thr Gly Val Pro Phe Pro Leu Asp Asn Asn Lys Ser
                 275                 280                 285

 Lys Pro Gly Gly Trp Leu Pro Leu Leu Leu Leu Ser Leu Leu Val
                 290                 295                 300

 Ala Thr Trp Val Leu Val Ala Gly Ile Tyr Leu Met Trp Arg His
                 305                 310                 315

 Glu Arg Ile Lys Lys Thr Ser Phe Ser Thr Thr Thr Leu Leu Pro
                 320                 325                 330

 Pro Ile Lys Val Leu Val Val Tyr Pro Ser Glu Ile Cys Phe His
                 335                 340                 345

 His Thr Ile Cys Tyr Phe Thr Glu Phe Leu Gln Asn His Cys Arg
                 350                 355                 360

 Ser Glu Val Ile Leu Glu Lys Trp Gln Lys Lys Lys Ile Ala Glu
                 365                 370                 375

 Met Gly Pro Val Gln Trp Leu Ala Thr Gln Lys Lys Ala Ala Asp
                 380                 385                 390

 Lys Val Val Phe Leu Leu Ser Asn Asp Val Asn Ser Val Cys Asp
                 395                 400                 405

 Gly Thr Cys Gly Lys Ser Glu Gly Ser Pro Ser Glu Asn Ser Gln
                 410                 415                 420

 Asp Leu Phe Pro Leu Ala Phe Asn Leu Phe Cys Ser Asp Leu Arg
                 425                 430                 435

 Ser Gln Ile His Leu His Lys Tyr Val Val Val Tyr Phe Arg Glu
                 440                 445                 450

 Ile Asp Thr Lys Asp Asp Tyr Asn Ala Leu Ser Val Cys Pro Lys
                 455                 460                 465

 Tyr His Leu Met Lys Asp Ala Thr Ala Phe Cys Ala Glu Leu Leu
                 470                 475                 480

 His Val Lys Gln Gln Val Ser Ala Gly Lys Arg Ser Gln Ala Cys
                 485                 490                 495

 His Asp Gly Cys Cys Ser Leu
                 500

<210> 3997
<211> 744
<212> DNA
<213> Homo sapien

<400> 3997
 ggaagcggag ggggagcagg tttgcggggc caagtgttgc ggcgacgcac 50

 ctcacgtcga gaatcgggag gaggagactg caaggatagg cccaggagta 100

 atggagtcca aagaggaacg agcgttaaac aatctcatcg tggaaaatgt 150

 caaccaggaa aatgatgaaa aagatgaaaa ggagcaagtt gctaataaag 200

 gggagccctt ggccctacct ttgaatgtta gtgaatactg tgtgcctaga 250

 ggaaaccgta ggcggttccg cgttaggcag cccatcctgc agtatagatg 300

 ggacataatg cataggcttg gagagccaca ggcaaggatg agagaggaga 350

 atatggaaag gattggggag gaggtgagac agctgatgga aaagctgagg 400

 gaaaagcagt tgagtcatag tctgcgggca gtcagcactg atccccctca 450

 ccatgaccat cacgatgagt tttgccttat gccctgaatc ctgatggttt 500

 ccctgaagtt aatagggaga cccctgcttc ctaaacttac acatttgtgg 550

 tgtacctttg tcgtaaacgt tttgatgtta cctatttctt gtgggtctcc 600

 tattaccagc ttctaaatga atgttgtttt tgacccagtt tgtaagtttc 650

 tgtcagcagg agagttttac ctattgcatg gaaggatgct cattatatat 700

 tgtgaagtta ataaaacagt tttaaaaagc aaaaaaaaaa aaaa 744

<210> 3998
<211> 128
<212> PRT
<213> Homo sapien

<400> 3998
 Met Glu Ser Lys Glu Glu Arg Ala Leu Asn Asn Leu Ile Val Glu
   1               5                  10                  15

 Asn Val Asn Gln Glu Asn Asp Glu Lys Asp Glu Lys Glu Gln Val
                  20                  25                  30

 Ala Asn Lys Gly Glu Pro Leu Ala Leu Pro Leu Asn Val Ser Glu
                  35                  40                  45

 Tyr Cys Val Pro Arg Gly Asn Arg Arg Arg Phe Arg Val Arg Gln
                  50                  55                  60

 Pro Ile Leu Gln Tyr Arg Trp Asp Ile Met His Arg Leu Gly Glu
                  65                  70                  75

 Pro Gln Ala Arg Met Arg Glu Glu Asn Met Glu Arg Ile Gly Glu
                  80                  85                  90

 Glu Val Arg Gln Leu Met Glu Lys Leu Arg Glu Lys Gln Leu Ser
                  95                 100                 105

 His Ser Leu Arg Ala Val Ser Thr Asp Pro Pro His His Asp His
                 110                 115                 120

 His Asp Glu Phe Cys Leu Met Pro
                 125

<210> 3999
<211> 2963
<212> DNA
<213> Homo sapien

<400> 3999
 gctgctgcac tgacggcggg tgcccgcgcc tcagagttac tgatttattc 50

 ttgagattcc tctactctcg ttatctgacc tcatggatga acttcaggat 100

 gttcagctca cagagatcaa accacttcta aatgataaga atggtacaag 150

 aaacttccag gactttgact gtcaggaaca tgatatagaa acaactcatg 200

 gtgtggtcca cgtcactata agaggcttac ccaaaggaaa cagaccagtt 250

 atactaacat atcatgacat tggcctcaac cataaatcct gtttcaatgc 300

 attctttaac tttgaggata tgcaagagat cacccagcac tttgctgtct 350

 gtcatgtgga tgccccaggc cagcaggaag gtgcaccctc tttcccaaca 400

 gggtatcagt accccacaat ggatgagctg gctgaaatgc tgcctcctgt 450

 tcttacccac ctaagcctga aaagcatcat tggaattgga gttggagctg 500

 gagcttacat cctcagcaga tttgcactca accatccaga gcttgtggaa 550

 ggccttgtgc tcattaatgt tgacccttgc gctaaaggct ggattgactg 600

 ggcagcttcc aaactctctg gcctgacaac caatgttgtg gacattattt 650

 tggctcatca ctttgggcag gaagagttac aggccaacct ggacctgatc 700

 caaacctaca gaatgcatat tgcccaagac atcaaccaag acaacctgca 750

 gctcttcttg aattcctaca atggacgcag agacctggag atcgaaagac 800

 ccatactggg ccaaaatgat aacaaatcaa aaacattaaa gtgttctact 850

 ttactggtgg taggggacaa ttcgcctgca gttgaggctg tggtcgaatg 900

 caattcccgc ctgaacccta taaatacaac tttgctaaag atggcggact 950

 gtgggggact gccccaggta gttcagcctg ggaagctcac cgaggccttc 1000

 aagtactttt tgcagggaat gggctacata ccatctgcca gcatgactcg 1050

 gctcgcccga tcacgaaccc actcaacctc gagtagcctc ggctctggag 1100

 aaagtccctt cagccggtct gtcaccagca atcagtcaga tggaactcaa 1150

 gaatcctgtg agtcccctga tgtcctggac agacaccaga ccatggaggt 1200

 gtcctgctaa gcagatgctc ctcccctgga ccattgcaag tccatccttc 1250

 aaatgaccac tccataatat aacatttcat ccagtaaact ggcctctact 1300

 atctttaact catgcatggc cactgaacct ctctctagta gcctggattt 1350

 atcattctct ctgcctgccc accccctttt ttgtatagcc caagaaccac 1400

 ttccatgcca tactgtaaca ttccaacatc tttagctgat cagatctctc 1450

 catatcctct cttgccagct ttttcccgtg ctcccccaac tatgtatcag 1500

 ataagattct ttgatcccga ctctgtgtgt gcgagcacgc gtgtctgtgt 1550

 ttgtgtgtgc atagttctgt ggttttagac acgctttctt gtagtgcttc 1600

 tgcaaaaaac aaaaaaggga cttattttgc attctcaatg gtgtttttaa 1650

 gggaattagg cagaacagat ttctaggttg ggtaggccac tgcattctct 1700

 tttgtttgca aattggtcaa caaaatttgc aaagtgattt caggagagag 1750

 cagctttgag gaatgtggaa aatcataatt gccgtctgga ccattgattg 1800

 attgtgacca gtagcagaag ggtgcctgtt acatagagag gctccttctg 1850

 tccaaatgaa tttctgtata ctcttctata aataaaaggg aggaatatat 1900

 tctgctggaa gcccatgaac catcgctgag gttctgatac aacatagagt 1950

 tttttccaag gagtgaatgt ggtttaatta ctggactctc ttagcacagg 2000

 aaggtggaaa caaaatgcca ggcctctgct ctgaagagca aaactgctgt 2050

 cgctgcagta tctgatacca gacatccaca tatccacaag aagtgcctct 2100

 taggtctgtg acagagagtg tgtctccatt cctcagttcc cagaaagggg 2150

 agaggtttgg cctaaaaagc atgtagatgg gggagaaatg ggtgggggga 2200

 gaggaacagc cattaacaca gtatcatgtt taacaagtat agccttgatt 2250

 tcagtagatg taatggaagc caaattaaat tgatacagaa cccatttctc 2300

 agagtctttt tttttttttt tgagacagag tctcgctgtt acccaggctg 2350

 gagtgcaatg gcgcaaactt ggctcactgc aacctctgcc ccctgggttc 2400

 aagcgattct cctgcctcag cctcccgagt agctgagact acaggcacct 2450

 gccaccatac ccagctaagt tatgtatttt tagtagagat ggagtttcac 2500

 catgttggcc aggctggtct caaactcctg acctcaggtg atccacctgc 2550

 ctcagcctcc caaagtgctg ggattacagg catgagtcat tgctcccagc 2600

 cattagaaag attgttaatc ctatgaactc ccttttgtag gagagaaagg 2650

 gccaatctgt aggggtagcc ctgtccaggt aaagttgttt tcagcctcat 2700

 gtctactgtt aggtgaggga gtcacagcca gacagagagt attgctggag 2750

 ggtgagagaa ttgtggagac caactaccac atagcaagag cccagctctt 2800

 gggagcattg agatgtaagc tcagggttac acagttccaa atcttgggaa 2850

 ggggcttttc agacagactg tttgctttct gctgagataa ggaatgcatc 2900

 actctgccag agtatgactt tttacagatt attaaataaa gctgcatatg 2950

 tctcattgtt acc 2963

<210> 4000
<211> 375
<212> PRT
<213> Homo sapien

<400> 4000
 Met Asp Glu Leu Gln Asp Val Gln Leu Thr Glu Ile Lys Pro Leu
   1               5                  10                  15

 Leu Asn Asp Lys Asn Gly Thr Arg Asn Phe Gln Asp Phe Asp Cys
                  20                  25                  30

 Gln Glu His Asp Ile Glu Thr Thr His Gly Val Val His Val Thr
                  35                  40                  45

 Ile Arg Gly Leu Pro Lys Gly Asn Arg Pro Val Ile Leu Thr Tyr
                  50                  55                  60

 His Asp Ile Gly Leu Asn His Lys Ser Cys Phe Asn Ala Phe Phe
                  65                  70                  75

 Asn Phe Glu Asp Met Gln Glu Ile Thr Gln His Phe Ala Val Cys
                  80                  85                  90

 His Val Asp Ala Pro Gly Gln Gln Glu Gly Ala Pro Ser Phe Pro
                  95                 100                 105

 Thr Gly Tyr Gln Tyr Pro Thr Met Asp Glu Leu Ala Glu Met Leu
                 110                 115                 120

 Pro Pro Val Leu Thr His Leu Ser Leu Lys Ser Ile Ile Gly Ile
                 125                 130                 135

 Gly Val Gly Ala Gly Ala Tyr Ile Leu Ser Arg Phe Ala Leu Asn
                 140                 145                 150

 His Pro Glu Leu Val Glu Gly Leu Val Leu Ile Asn Val Asp Pro
                 155                 160                 165

 Cys Ala Lys Gly Trp Ile Asp Trp Ala Ala Ser Lys Leu Ser Gly
                 170                 175                 180

 Leu Thr Thr Asn Val Val Asp Ile Ile Leu Ala His His Phe Gly
                 185                 190                 195

 Gln Glu Glu Leu Gln Ala Asn Leu Asp Leu Ile Gln Thr Tyr Arg
                 200                 205                 210

 Met His Ile Ala Gln Asp Ile Asn Gln Asp Asn Leu Gln Leu Phe
                 215                 220                 225

 Leu Asn Ser Tyr Asn Gly Arg Arg Asp Leu Glu Ile Glu Arg Pro
                 230                 235                 240

 Ile Leu Gly Gln Asn Asp Asn Lys Ser Lys Thr Leu Lys Cys Ser
                 245                 250                 255

 Thr Leu Leu Val Val Gly Asp Asn Ser Pro Ala Val Glu Ala Val
                 260                 265                 270

 Val Glu Cys Asn Ser Arg Leu Asn Pro Ile Asn Thr Thr Leu Leu
                 275                 280                 285

 Lys Met Ala Asp Cys Gly Gly Leu Pro Gln Val Val Gln Pro Gly
                 290                 295                 300

 Lys Leu Thr Glu Ala Phe Lys Tyr Phe Leu Gln Gly Met Gly Tyr
                 305                 310                 315

 Ile Pro Ser Ala Ser Met Thr Arg Leu Ala Arg Ser Arg Thr His
                 320                 325                 330

 Ser Thr Ser Ser Ser Leu Gly Ser Gly Glu Ser Pro Phe Ser Arg
                 335                 340                 345

 Ser Val Thr Ser Asn Gln Ser Asp Gly Thr Gln Glu Ser Cys Glu
                 350                 355                 360

 Ser Pro Asp Val Leu Asp Arg His Gln Thr Met Glu Val Ser Cys
                 365                 370                 375

<210> 4001
<211> 2824
<212> DNA
<213> Homo sapien

<400> 4001
 cccgagcccc gcccctccgg gcccgggtcg gcgcgcccag cctgccagcc 50

 gcgctgctgc tgctcctcct gctgtgggac cgctgaccgc gcggctgctc 100

 cgctctcccc gctccaagcg ccgatctggg cacccgccac cagcatggac 150

 gctcgccgcg tgccgcagaa agatctcaga gtaaagaaga acttaaagaa 200

 attcagatat gtgaagttga tttccatgga aacctcgtca tcctctgatg 250

 acagttgtga cagctttgct tctgataatt ttgcaaacac gaaacctaaa 300

 ttcaggtcag atatcagtga agaactggca agtgtttttt atgaggactc 350

 tgataatgaa tctttctgcg gcttttcaga aagtgaggtg caagatgtat 400

 tagaccattg tggattttta cagaaaccaa ggccagatgt cactaacgaa 450

 ctggccggta tttttcatgc cgactctgac gatgaatcat tttgcggttt 500

 ctcagagagt gagatacaag atggaatgag gctgcagtca gttcgggaag 550

 gctgtaggac ccgcagccag tgcaggcact ctggacctct cagggtggcg 600

 atgaagtttc cagcgcggag taccagggga gcaaccaaca aaaaagcaga 650

 gtcccgccag ccctcagaga attctgtgac tgattccaac tccgattcag 700

 aagatgaaag tggaatgaat tttttggaga aaagggcttt aaatataaag 750

 caaaacaaag caatgcttgc aaaactcatg tctgaattag aaagcttccc 800

 tggctcgttc cgtggaagac atcccctccc aggctccgac tcacaatcaa 850

 ggagaccgcg aaggcgtaca ttcccgggtg ttgcttccag gagaaaccct 900

 gaacggagag ctcgtcctct taccaggtca aggtcccgga tcctcgggtc 950

 ccttgacgct ctacccatgg aggaggagga ggaagaggat aagtacatgt 1000

 tggtgagaaa gaggaagacc gtggatggct acatgaatga agatgacctg 1050

 cccagaagcc gtcgctccag atcatccgtg acccttccgc atataattcg 1100

 cccagtggaa gaaattacag aggaggagtt ggagaacgtc tgcagcaatt 1150

 ctcgagagaa gatatataac cgttcactgg gctctacttg tcatcaatgc 1200

 cgtcagaaga ctattgatac caaaacaaac tgcagaaacc cagactgctg 1250

 gggcgttcga ggccagttct gtggcccctg ccttcgaaac cgttatggtg 1300

 aagaggtcag ggatgctctg ctggatccga actggcattg cccgccttgt 1350

 cgaggaatct gcaactgcag tttctgccgg cagcgagatg gacggtgtgc 1400

 gactggggtc cttgtgtatt tagccaaata tcatggcttt gggaatgtgc 1450

 atgcctactt gaaaagcctg aaacaggaat ttgaaatgca agcataatat 1500

 ctggaaaatt tgctgcctgc cttctacttc tcaaatcttt cttgtaaaag 1550

 tttccaattt tttcactgaa acctgagtta aaaatcttga tgatcagcct 1600

 gtttcataag aaactccaat caagttaatc ttagcagaca tgtgtttctg 1650

 gagcatcaca gaaggtatat tgctagttac actttgccct cctgcagttt 1700

 cttctctgct cccaaccccc atctcatagc atccccctct atttccaatg 1750

 ctcctctcca accgcttagt ttctgaattt cttttaaatt acagttttat 1800

 gaaagcatat tttatttact tggtgttgaa atagccctca taaaacctaa 1850

 gcacttggaa acacaataat agtattaact aactagatct attgaatttc 1900

 agagaagagc cttctaactt gtttacacaa aaacgagtat gatttagcat 1950

 tcatactagt tgaaattttt aatagaatca aggcacaaaa gtcttaaaac 2000

 catgtggaaa aattaggtaa ttattgcaga ttgatgtctc tcaatcccat 2050

 gtattgcgct tatgttacaa gttgttgtca cagttgagac ttaatttctc 2100

 ctaatttctt ctgcccgaag ggtaagtggt gcgtccagct tacacaatca 2150

 taattcaaag gttggtgggc aatgtaatac ttaattaaaa taatgatgga 2200

 agagctatct ggagattatg agtaagctga tttgaatttt cagtataaaa 2250

 ctttagtata attgtagttt gcaaagttta tttcagttca catgtaaggt 2300

 attgcaaata aattcttgga caattttgta tggaaacttg atattaaaaa 2350

 ctagtctgtg gttctttgca gtttcttgta aatttataaa ccaggcacaa 2400

 ggttcaagtt tagattttaa gcacttttat aacaatgata agtgcctttt 2450

 tggagatgta acttttagca gtttgttaac ctgacatctc tgccagtcta 2500

 gtttctgggc aggtttcctg tgtcagtatt ccccctcctc tttgcattaa 2550

 tcaaggtatt tggtagaggt ggaatctaag tgtttgtatg tccaatttac 2600

 ttgcatatgt aaaccattgc tgtgccattc aatgtttgat gcataattgg 2650

 accttgaatc gataagtgta aatacagctt ttgatctgta atgcttttat 2700

 acaaaagttt attttaataa taaaatgttt gttctaactt gtctgctttt 2750

 ttaaaaataa tcttactgta cttaattcta attttttcct catatttaaa 2800

 taaaaggcca tttccacctt ttct 2824

<210> 4002
<211> 450
<212> PRT
<213> Homo sapien

<400> 4002
 Met Asp Ala Arg Arg Val Pro Gln Lys Asp Leu Arg Val Lys Lys
   1               5                  10                  15

 Asn Leu Lys Lys Phe Arg Tyr Val Lys Leu Ile Ser Met Glu Thr
                  20                  25                  30

 Ser Ser Ser Ser Asp Asp Ser Cys Asp Ser Phe Ala Ser Asp Asn
                  35                  40                  45

 Phe Ala Asn Thr Lys Pro Lys Phe Arg Ser Asp Ile Ser Glu Glu
                  50                  55                  60

 Leu Ala Ser Val Phe Tyr Glu Asp Ser Asp Asn Glu Ser Phe Cys
                  65                  70                  75

 Gly Phe Ser Glu Ser Glu Val Gln Asp Val Leu Asp His Cys Gly
                  80                  85                  90

 Phe Leu Gln Lys Pro Arg Pro Asp Val Thr Asn Glu Leu Ala Gly
                  95                 100                 105

 Ile Phe His Ala Asp Ser Asp Asp Glu Ser Phe Cys Gly Phe Ser
                 110                 115                 120

 Glu Ser Glu Ile Gln Asp Gly Met Arg Leu Gln Ser Val Arg Glu
                 125                 130                 135

 Gly Cys Arg Thr Arg Ser Gln Cys Arg His Ser Gly Pro Leu Arg
                 140                 145                 150

 Val Ala Met Lys Phe Pro Ala Arg Ser Thr Arg Gly Ala Thr Asn
                 155                 160                 165

 Lys Lys Ala Glu Ser Arg Gln Pro Ser Glu Asn Ser Val Thr Asp
                 170                 175                 180

 Ser Asn Ser Asp Ser Glu Asp Glu Ser Gly Met Asn Phe Leu Glu
                 185                 190                 195

 Lys Arg Ala Leu Asn Ile Lys Gln Asn Lys Ala Met Leu Ala Lys
                 200                 205                 210

 Leu Met Ser Glu Leu Glu Ser Phe Pro Gly Ser Phe Arg Gly Arg
                 215                 220                 225

 His Pro Leu Pro Gly Ser Asp Ser Gln Ser Arg Arg Pro Arg Arg
                 230                 235                 240

 Arg Thr Phe Pro Gly Val Ala Ser Arg Arg Asn Pro Glu Arg Arg
                 245                 250                 255

 Ala Arg Pro Leu Thr Arg Ser Arg Ser Arg Ile Leu Gly Ser Leu
                 260                 265                 270

 Asp Ala Leu Pro Met Glu Glu Glu Glu Glu Glu Asp Lys Tyr Met
                 275                 280                 285

 Leu Val Arg Lys Arg Lys Thr Val Asp Gly Tyr Met Asn Glu Asp
                 290                 295                 300

 Asp Leu Pro Arg Ser Arg Arg Ser Arg Ser Ser Val Thr Leu Pro
                 305                 310                 315

 His Ile Ile Arg Pro Val Glu Glu Ile Thr Glu Glu Glu Leu Glu
                 320                 325                 330

 Asn Val Cys Ser Asn Ser Arg Glu Lys Ile Tyr Asn Arg Ser Leu
                 335                 340                 345

 Gly Ser Thr Cys His Gln Cys Arg Gln Lys Thr Ile Asp Thr Lys
                 350                 355                 360

 Thr Asn Cys Arg Asn Pro Asp Cys Trp Gly Val Arg Gly Gln Phe
                 365                 370                 375

 Cys Gly Pro Cys Leu Arg Asn Arg Tyr Gly Glu Glu Val Arg Asp
                 380                 385                 390

 Ala Leu Leu Asp Pro Asn Trp His Cys Pro Pro Cys Arg Gly Ile
                 395                 400                 405

 Cys Asn Cys Ser Phe Cys Arg Gln Arg Asp Gly Arg Cys Ala Thr
                 410                 415                 420

 Gly Val Leu Val Tyr Leu Ala Lys Tyr His Gly Phe Gly Asn Val
                 425                 430                 435

 His Ala Tyr Leu Lys Ser Leu Lys Gln Glu Phe Glu Met Gln Ala
                 440                 445                 450

<210> 4003
<211> 2495
<212> DNA
<213> Homo sapien

<400> 4003
 gggtggtgga tctgtcggtc ccgttttccc gtcgcacgtg gtggccactg 50

 ttggcttctg aatggtttgc aaggcggata tccacgccaa ggcctttgga 100

 tcggccgtgg gtacatccgt ctgagccgtt cctttccatc gcagagcggc 150

 ggcctccggc ggcgctctcc agtcatggac taccggcggc ttctcatgag 200

 ccgggtggtc cccgggcaat tcgacgacgc ggactcctct gacagtgaaa 250

 acagagactt gaagacagtc aaagagaagg atgacattct gtttgaagac 300

 cttcaagaca atgtgaatga gaatggtgaa ggtgaaatag aagatgagga 350

 ggaggagggt tatgacgatg atgatgatga ctgggactgg gatgaaggag 400

 ttggaaaact cgccaagggt tatgtctgga atggaggaag caacccacag 450

 gcaaatcgac agacctccga cagcagttca gccaaaatgt ctactccagc 500

 agacaaggtc ttacggaaat ttgagaataa aattaattta gataagctaa 550

 atgttactga ttccgtcata aataaagtca ccgaaaagtc tagacaaaag 600

 gaagcagata tgtatcgcat caaagataag gcagacagag caactgtaga 650

 acaggtgttg gatcccagaa caagaatgat tttattcaag atgttgacta 700

 gaggaatcat aacagagata aatggctgca ttagcacagg aaaagaagct 750

 aatgtatacc atgctagcac agcaaatgga gagagcagag caatcaaaat 800

 ttataaaact tctattttgg tgttcaaaga tcgggataaa tatgtaagtg 850

 gagaattcag atttcgtcat ggctattgta aaggaaaccc taggaaaatg 900

 gtgaaaactt gggcagaaaa agaaatgagg aacttaatca ggctaaacac 950

 agcagagata ccatgtccag aaccaataat gctaagaagt catgttcttg 1000

 tcatgagttt catcggtaaa gatgacatgc ctgcaccact cttgaaaaat 1050

 gtccagttat cagaatccaa ggctcgggag ttgtacctgc aggtcattca 1100

 gtacatgaga agaatgtatc aggatgccag acttgtccat gcagatctca 1150

 gtgaatttaa catgctgtac cacggtggag gcgtgtatat cattgacgtg 1200

 tctcagtccg tggagcacga ccacccacat gccttggagt tcttgagaaa 1250

 ggattgcgcc aacgtcaatg atttctttat gaggcacagt gttgctgtca 1300

 tgactgtgcg ggagctcttt gaatttgtca cagatccatc cattacacat 1350

 gagaacatgg atgcttatct ctcaaaggcc atggaaatag catctcaaag 1400

 gaccaaggaa gaacggtcta gccaagatca tgtggatgaa gaggtgttta 1450

 agcgagcata tattcctaga accttgaatg aagtgaaaaa ttatgagagg 1500

 gatatggaca taattatgaa attgaaggaa gaggacatgg ccatgaatgc 1550

 ccaacaagat aatattctat accagactgt tacaggattg aagaaagatt 1600

 tgtcaggagt tcagaaggtc cctgcactcc tagaaaatca agtggaggaa 1650

 aggacttgtt ctgattcaga agatattgga agctctgagt gctctgacac 1700

 agactctgaa gagcagggag accatgcccg ccccaagaaa cacaccacgg 1750

 accctgacat tgataaaaaa gaaagaaaaa agatggtcaa ggaagcccag 1800

 agagagaaaa gaaaaaacaa aattcctaaa catgtgaaaa aaagaaagga 1850

 gaagacagcc aagacgaaaa aaggcaaata gaatgagaac catattatgt 1900

 acagtcattt tcctcagttc cttttctcgc ctgaactctt aagctgcatc 1950

 tggaagatgg cttattggtt ttaaccagat tgtcatcgtg gcactgtctg 2000

 tgaagacgga ttcaaatgtt ttcatgtaac tatgtaaaaa gctctaagct 2050

 ctagagtcta gatccagtca ctgactctgt ctggtgttga cagaggattt 2100

 atttaagcta ttattttaat aaagaacttt gtacattttt atttttatat 2150

 ttttttctct tacaaatatg tttttggaag catgataaat gtttaaatgt 2200

 agtcaacatc tgtaactctt acatgagtgt ccagaggcac tcatgggaaa 2250

 attggttttg ctttctttgt acacaccaga gacccatctg aggtcatctg 2300

 attataaggc catgtttata taaagggaat ttcacccaca gttcagctgg 2350

 ctgttgattt tcactgcaac tctgcctttg tgtgtattgg cgatcatttg 2400

 taatgctctt acacttcgtc tttaatgttc tttttggagt taggacctct 2450

 cagttcataa agttttttac aattcaaaaa aaaaaaaaaa aaaaa 2495

<210> 4004
<211> 568
<212> PRT
<213> Homo sapien

<400> 4004
 Met Asp Tyr Arg Arg Leu Leu Met Ser Arg Val Val Pro Gly Gln
   1               5                  10                  15

 Phe Asp Asp Ala Asp Ser Ser Asp Ser Glu Asn Arg Asp Leu Lys
                  20                  25                  30

 Thr Val Lys Glu Lys Asp Asp Ile Leu Phe Glu Asp Leu Gln Asp
                  35                  40                  45

 Asn Val Asn Glu Asn Gly Glu Gly Glu Ile Glu Asp Glu Glu Glu
                  50                  55                  60

 Glu Gly Tyr Asp Asp Asp Asp Asp Asp Trp Asp Trp Asp Glu Gly
                  65                  70                  75

 Val Gly Lys Leu Ala Lys Gly Tyr Val Trp Asn Gly Gly Ser Asn
                  80                  85                  90

 Pro Gln Ala Asn Arg Gln Thr Ser Asp Ser Ser Ser Ala Lys Met
                  95                 100                 105

 Ser Thr Pro Ala Asp Lys Val Leu Arg Lys Phe Glu Asn Lys Ile
                 110                 115                 120

 Asn Leu Asp Lys Leu Asn Val Thr Asp Ser Val Ile Asn Lys Val
                 125                 130                 135

 Thr Glu Lys Ser Arg Gln Lys Glu Ala Asp Met Tyr Arg Ile Lys
                 140                 145                 150

 Asp Lys Ala Asp Arg Ala Thr Val Glu Gln Val Leu Asp Pro Arg
                 155                 160                 165

 Thr Arg Met Ile Leu Phe Lys Met Leu Thr Arg Gly Ile Ile Thr
                 170                 175                 180

 Glu Ile Asn Gly Cys Ile Ser Thr Gly Lys Glu Ala Asn Val Tyr
                 185                 190                 195

 His Ala Ser Thr Ala Asn Gly Glu Ser Arg Ala Ile Lys Ile Tyr
                 200                 205                 210

 Lys Thr Ser Ile Leu Val Phe Lys Asp Arg Asp Lys Tyr Val Ser
                 215                 220                 225

 Gly Glu Phe Arg Phe Arg His Gly Tyr Cys Lys Gly Asn Pro Arg
                 230                 235                 240

 Lys Met Val Lys Thr Trp Ala Glu Lys Glu Met Arg Asn Leu Ile
                 245                 250                 255

 Arg Leu Asn Thr Ala Glu Ile Pro Cys Pro Glu Pro Ile Met Leu
                 260                 265                 270

 Arg Ser His Val Leu Val Met Ser Phe Ile Gly Lys Asp Asp Met
                 275                 280                 285

 Pro Ala Pro Leu Leu Lys Asn Val Gln Leu Ser Glu Ser Lys Ala
                 290                 295                 300

 Arg Glu Leu Tyr Leu Gln Val Ile Gln Tyr Met Arg Arg Met Tyr
                 305                 310                 315

 Gln Asp Ala Arg Leu Val His Ala Asp Leu Ser Glu Phe Asn Met
                 320                 325                 330

 Leu Tyr His Gly Gly Gly Val Tyr Ile Ile Asp Val Ser Gln Ser
                 335                 340                 345

 Val Glu His Asp His Pro His Ala Leu Glu Phe Leu Arg Lys Asp
                 350                 355                 360

 Cys Ala Asn Val Asn Asp Phe Phe Met Arg His Ser Val Ala Val
                 365                 370                 375

 Met Thr Val Arg Glu Leu Phe Glu Phe Val Thr Asp Pro Ser Ile
                 380                 385                 390

 Thr His Glu Asn Met Asp Ala Tyr Leu Ser Lys Ala Met Glu Ile
                 395                 400                 405

 Ala Ser Gln Arg Thr Lys Glu Glu Arg Ser Ser Gln Asp His Val
                 410                 415                 420

 Asp Glu Glu Val Phe Lys Arg Ala Tyr Ile Pro Arg Thr Leu Asn
                 425                 430                 435

 Glu Val Lys Asn Tyr Glu Arg Asp Met Asp Ile Ile Met Lys Leu
                 440                 445                 450

 Lys Glu Glu Asp Met Ala Met Asn Ala Gln Gln Asp Asn Ile Leu
                 455                 460                 465

 Tyr Gln Thr Val Thr Gly Leu Lys Lys Asp Leu Ser Gly Val Gln
                 470                 475                 480

 Lys Val Pro Ala Leu Leu Glu Asn Gln Val Glu Glu Arg Thr Cys
                 485                 490                 495

 Ser Asp Ser Glu Asp Ile Gly Ser Ser Glu Cys Ser Asp Thr Asp
                 500                 505                 510

 Ser Glu Glu Gln Gly Asp His Ala Arg Pro Lys Lys His Thr Thr
                 515                 520                 525

 Asp Pro Asp Ile Asp Lys Lys Glu Arg Lys Lys Met Val Lys Glu
                 530                 535                 540

 Ala Gln Arg Glu Lys Arg Lys Asn Lys Ile Pro Lys His Val Lys
                 545                 550                 555

 Lys Arg Lys Glu Lys Thr Ala Lys Thr Lys Lys Gly Lys
                 560                 565

<210> 4005
<211> 2221
<212> DNA
<213> Homo sapien

<400> 4005
 gtgaccggag gcgagaaacc ccgcctcggc accctgacgc agcgcaggac 50

 ccgccccgcg cgtgacgcca gcgtcaggcc agccccggca tgctctgcgg 100

 ccgcccgcgg tccagctccg acaacaggaa ttttctccga gagcgggccg 150

 ggctcagttc agctgctgtc cagacccgga tcggcaacag tgccgcctcc 200

 agacgttctc ctgccgctcg cccgcccgtc ccagcgcccc cagccctccc 250

 gcgagggcgc cccgggacgg aaggatccac cagtctgtcg gcgcccgccg 300

 ttctcgtggt cgccgtcgcc gtcgtcgtgg tggtagtctc cgccgtcgcc 350

 tgggccatgg ccaattacat ccacgtccct cccggctccc cggaggtgcc 400

 caagctgaac gtcaccgttc aggatcagga ggagcatcgc tgccgggagg 450

 gggccctgag cctcctgcaa cacctgcggc ctcactggga cccccaggag 500

 gtgaccctgc agctcttcac agatggaatc acaaataaac ttattggctg 550

 ttacgtggga aacaccatgg aggatgtagt cctggtgaga atttatggca 600

 ataagactga gttattagtc gatcgagatg aggaagtaaa gagttttcga 650

 gtgttgcagg ctcatgggtg tgcaccacaa ctctactgta ccttcaataa 700

 tggactatgc tatgaattta tacaaggaga agcactggat ccaaagcatg 750

 tctgcaaccc agccattttc aggctaatag ctcgtcagct tgctaaaatc 800

 catgctattc atgcacacaa tggctggatc cccaaatcta atctttggct 850

 aaagatggga aagtatttct ctctcattcc cacaggattt gcagatgaag 900

 acattaataa aaggttccta agtgatatcc caagctctca gattctccag 950

 gaagagatga cttggatgaa ggagattctt tccaacctgg gctcacctgt 1000

 tgtgctttgc cataatgacc tattgtgtaa gaatataatc tacaatgaga 1050

 aacaaggtga tgtacagttc attgattatg aatattctgg atacaactac 1100

 ctggcatatg atattggaaa tcatttcaat gaatttgcag gtgtgagtga 1150

 tgtagactat agtctgtatc cagatagaga actacagagt cagtggctgc 1200

 gtgcttacct tgaagcctac aaagaattta agggctttgg gactgaagtt 1250

 actgaaaagg aggtagaaat actcttcatt caagtcaatc agtttgcatt 1300

 ggcttctcat ttcttttggg gattgtgggc tttgattcaa gccaaatact 1350

 ccactattga gtttgatttc cttgggtatg caattgttcg ttttaaccag 1400

 tactttaaaa tgaagcctga ggttactgca ttaaaagtgc ctgagtaaag 1450

 aagagattta attattctcc agtagctgag caatgcttgt gaatcttttc 1500

 ttaagaaatc ccaaaaagcc aatattagtt aaaattctgt tgtttaattt 1550

 ggttatcttg ctttataaat tatgcctcta aacaatcaaa tctatttttg 1600

 aaatagactg aatgatgtca agaaatatac ctactgctat ccgtatgtgg 1650

 tggattagaa atgtgttaaa tctgcaaaag gtataaagat gtcagtttaa 1700

 tttctttgat aatttaacct atgttgtatg tgaattattt attataaact 1750

 tagcacgatt ctgtgactgt ttttctctgt ttcacgttcg ttgagtgtaa 1800

 gcaatgaaaa tgtcccaaat aagtttttta agttttactt taataagatt 1850

 aatttcagta aacattctag ttgttcagtg taaccttttt atcttgatgc 1900

 attgtaagta aaatgaatca tttactcttg aaatgccagt cattgactga 1950

 tgtagataat ttaggatttt catataaaaa tagctgttta ggaaggtgaa 2000

 atacattcac tgtctctgtt ggtggtacat cttgttgaat tcaatattag 2050

 aaagtatttc tttttggggt aatataactt agaattaaat ccctgtttct 2100

 ctatgtagtc tggcagtata aatataaata tttaccatat aatcttggaa 2150

 taagtattag ttaatgttac caaaatctgt attaaataat gttttcaaat 2200

 gctaaaaaaa aaaaaaaaaa a 2221

<210> 4006
<211> 452
<212> PRT
<213> Homo sapien

<400> 4006
 Met Leu Cys Gly Arg Pro Arg Ser Ser Ser Asp Asn Arg Asn Phe
   1               5                  10                  15

 Leu Arg Glu Arg Ala Gly Leu Ser Ser Ala Ala Val Gln Thr Arg
                  20                  25                  30

 Ile Gly Asn Ser Ala Ala Ser Arg Arg Ser Pro Ala Ala Arg Pro
                  35                  40                  45

 Pro Val Pro Ala Pro Pro Ala Leu Pro Arg Gly Arg Pro Gly Thr
                  50                  55                  60

 Glu Gly Ser Thr Ser Leu Ser Ala Pro Ala Val Leu Val Val Ala
                  65                  70                  75

 Val Ala Val Val Val Val Val Val Ser Ala Val Ala Trp Ala Met
                  80                  85                  90

 Ala Asn Tyr Ile His Val Pro Pro Gly Ser Pro Glu Val Pro Lys
                  95                 100                 105

 Leu Asn Val Thr Val Gln Asp Gln Glu Glu His Arg Cys Arg Glu
                 110                 115                 120

 Gly Ala Leu Ser Leu Leu Gln His Leu Arg Pro His Trp Asp Pro
                 125                 130                 135

 Gln Glu Val Thr Leu Gln Leu Phe Thr Asp Gly Ile Thr Asn Lys
                 140                 145                 150

 Leu Ile Gly Cys Tyr Val Gly Asn Thr Met Glu Asp Val Val Leu
                 155                 160                 165

 Val Arg Ile Tyr Gly Asn Lys Thr Glu Leu Leu Val Asp Arg Asp
                 170                 175                 180

 Glu Glu Val Lys Ser Phe Arg Val Leu Gln Ala His Gly Cys Ala
                 185                 190                 195

 Pro Gln Leu Tyr Cys Thr Phe Asn Asn Gly Leu Cys Tyr Glu Phe
                 200                 205                 210

 Ile Gln Gly Glu Ala Leu Asp Pro Lys His Val Cys Asn Pro Ala
                 215                 220                 225

 Ile Phe Arg Leu Ile Ala Arg Gln Leu Ala Lys Ile His Ala Ile
                 230                 235                 240

 His Ala His Asn Gly Trp Ile Pro Lys Ser Asn Leu Trp Leu Lys
                 245                 250                 255

 Met Gly Lys Tyr Phe Ser Leu Ile Pro Thr Gly Phe Ala Asp Glu
                 260                 265                 270

 Asp Ile Asn Lys Arg Phe Leu Ser Asp Ile Pro Ser Ser Gln Ile
                 275                 280                 285

 Leu Gln Glu Glu Met Thr Trp Met Lys Glu Ile Leu Ser Asn Leu
                 290                 295                 300

 Gly Ser Pro Val Val Leu Cys His Asn Asp Leu Leu Cys Lys Asn
                 305                 310                 315

 Ile Ile Tyr Asn Glu Lys Gln Gly Asp Val Gln Phe Ile Asp Tyr
                 320                 325                 330

 Glu Tyr Ser Gly Tyr Asn Tyr Leu Ala Tyr Asp Ile Gly Asn His
                 335                 340                 345

 Phe Asn Glu Phe Ala Gly Val Ser Asp Val Asp Tyr Ser Leu Tyr
                 350                 355                 360

 Pro Asp Arg Glu Leu Gln Ser Gln Trp Leu Arg Ala Tyr Leu Glu
                 365                 370                 375

 Ala Tyr Lys Glu Phe Lys Gly Phe Gly Thr Glu Val Thr Glu Lys
                 380                 385                 390

 Glu Val Glu Ile Leu Phe Ile Gln Val Asn Gln Phe Ala Leu Ala
                 395                 400                 405

 Ser His Phe Phe Trp Gly Leu Trp Ala Leu Ile Gln Ala Lys Tyr
                 410                 415                 420

 Ser Thr Ile Glu Phe Asp Phe Leu Gly Tyr Ala Ile Val Arg Phe
                 425                 430                 435

 Asn Gln Tyr Phe Lys Met Lys Pro Glu Val Thr Ala Leu Lys Val
                 440                 445                 450

 Pro Glu


<210> 4007
<211> 1369
<212> DNA
<213> Homo sapien

<400> 4007
 ggccgacagt gcctgatttg agatggggtc ccaggtctcg gtggaatcgg 50

 gagctctgca cgtggtgatt gtgggtgggg gctttggcgg gatcgcagca 100

 gccagccagc tgcaggccct gaacgtcccc ttcatgctgg tggacatgaa 150

 ggactccttc caccacaatg tggctgctct ccgagcctcc gtggagacag 200

 ggttcgccaa aaagacattc atttcttact cggtgacttt caaggacaac 250

 ttccggcagg ggctagtagt ggggatagac ctgaagaacc agatggtgct 300

 gctgcagggt ggcgaggccc tgcccttctc tcatcttatc ctggccacgg 350

 gcagcactgg gcccttcccg ggcaagttta atgaggtttc cagccagcag 400

 gccgctatcc aggcctatga ggacatggtg aggcaggtcc agcgctcacg 450

 gttcatcgtg gtggtgggag gaggctcggc tggagtggag atggcagcag 500

 agattaaaac agaatatcct gagaaagagg tcactctcat tcactcccaa 550

 gtggccctgg ctgacaagga gctcctgccc tccgtccggc aggaagtgaa 600

 ggagatcctc ctccggaagg gcgtgcagct gctgctgagt gagcgggtga 650

 gcaatctgga ggagctgcct ctcaatgagt atcgagagta catcaaagtg 700

 cagacggaca aaggcacaga ggtggccacc aacctggtga ttctctgcac 750

 cggcatcaag atcaacagct ccgcctaccg caaagcattt gagagcagac 800

 tagccagcag tggtgctctg agagtgaacg agcacctcca ggtggagggc 850

 cacagcaacg tctacgccat tggtgactgt gccgacgtga ggacgcccaa 900

 gatggcctat cttgccggcc tccacgccaa catcgccgtg gccaacatcg 950

 tcaactctgt gaagcagcgg cctctccagg cctacaagcc gggtgcactg 1000

 acgttcctcc tgtccatggg gagaaatgac ggtgtgggcc aaatcagtgg 1050

 cttctatgtg ggccggctca tggttcggct gaccaagagc cgggacctgt 1100

 tcgtctctac gagctggaaa accatgaggc agtctccacc ttgatggaga 1150

 ggccaggcgg gagaactacc gcagcaggtg ggcgtacgga ctgcttggcg 1200

 catggcaccc gcctggcaag tgctagaact aatgctattc ttctggaata 1250

 agatgccaat gatgtggtgg ctagaaatgc aacttgtata aaacaaaaat 1300

 gggagagaga gaggtattaa acaaataccc cccttagagg ataaaaaaaa 1350

 aaaaaaaaaa aaaaaaaaa 1369

<210> 4008
<211> 373
<212> PRT
<213> Homo sapien

<400> 4008
 Met Gly Ser Gln Val Ser Val Glu Ser Gly Ala Leu His Val Val
   1               5                  10                  15

 Ile Val Gly Gly Gly Phe Gly Gly Ile Ala Ala Ala Ser Gln Leu
                  20                  25                  30

 Gln Ala Leu Asn Val Pro Phe Met Leu Val Asp Met Lys Asp Ser
                  35                  40                  45

 Phe His His Asn Val Ala Ala Leu Arg Ala Ser Val Glu Thr Gly
                  50                  55                  60

 Phe Ala Lys Lys Thr Phe Ile Ser Tyr Ser Val Thr Phe Lys Asp
                  65                  70                  75

 Asn Phe Arg Gln Gly Leu Val Val Gly Ile Asp Leu Lys Asn Gln
                  80                  85                  90

 Met Val Leu Leu Gln Gly Gly Glu Ala Leu Pro Phe Ser His Leu
                  95                 100                 105

 Ile Leu Ala Thr Gly Ser Thr Gly Pro Phe Pro Gly Lys Phe Asn
                 110                 115                 120

 Glu Val Ser Ser Gln Gln Ala Ala Ile Gln Ala Tyr Glu Asp Met
                 125                 130                 135

 Val Arg Gln Val Gln Arg Ser Arg Phe Ile Val Val Val Gly Gly
                 140                 145                 150

 Gly Ser Ala Gly Val Glu Met Ala Ala Glu Ile Lys Thr Glu Tyr
                 155                 160                 165

 Pro Glu Lys Glu Val Thr Leu Ile His Ser Gln Val Ala Leu Ala
                 170                 175                 180

 Asp Lys Glu Leu Leu Pro Ser Val Arg Gln Glu Val Lys Glu Ile
                 185                 190                 195

 Leu Leu Arg Lys Gly Val Gln Leu Leu Leu Ser Glu Arg Val Ser
                 200                 205                 210

 Asn Leu Glu Glu Leu Pro Leu Asn Glu Tyr Arg Glu Tyr Ile Lys
                 215                 220                 225

 Val Gln Thr Asp Lys Gly Thr Glu Val Ala Thr Asn Leu Val Ile
                 230                 235                 240

 Leu Cys Thr Gly Ile Lys Ile Asn Ser Ser Ala Tyr Arg Lys Ala
                 245                 250                 255

 Phe Glu Ser Arg Leu Ala Ser Ser Gly Ala Leu Arg Val Asn Glu
                 260                 265                 270

 His Leu Gln Val Glu Gly His Ser Asn Val Tyr Ala Ile Gly Asp
                 275                 280                 285

 Cys Ala Asp Val Arg Thr Pro Lys Met Ala Tyr Leu Ala Gly Leu
                 290                 295                 300

 His Ala Asn Ile Ala Val Ala Asn Ile Val Asn Ser Val Lys Gln
                 305                 310                 315

 Arg Pro Leu Gln Ala Tyr Lys Pro Gly Ala Leu Thr Phe Leu Leu
                 320                 325                 330

 Ser Met Gly Arg Asn Asp Gly Val Gly Gln Ile Ser Gly Phe Tyr
                 335                 340                 345

 Val Gly Arg Leu Met Val Arg Leu Thr Lys Ser Arg Asp Leu Phe
                 350                 355                 360

 Val Ser Thr Ser Trp Lys Thr Met Arg Gln Ser Pro Pro
                 365                 370

<210> 4009
<211> 1174
<212> DNA
<213> Homo sapien

<400> 4009
 tagtttgcgt tttcacctgg tcgcccggcg gccatggcgg ccgttctgaa 50

 gccggtgctg ctgggccttc gagatgcgcc ggtgcacggc agccccacag 100

 ggccgggtgc ctggactgct agcaagctgg gcggcattcc ggatgctctg 150

 cccaccgtgg ctgcgcccag gcccgtgtgt cagcgctgcg ggcagccgct 200

 cgctctggtc gtgcaggtgt attgcccgct ggaaggctcc ccgtttcacc 250

 gtctgctgca cgtgttcgcg tgcgcctgcc ccggctgtag caccggcggt 300

 gcgcgcagct ggaaggtgtt ccgctcccag tgcctgcagg tgccagagag 350

 agaggcgcag gacgctcaga aacagggaaa cagccttgca gctgaggact 400

 ggtgtgaagg tgctgatgac tggggaagtg atactgagga ggggccttca 450

 ccacagttta ccttggattt tgggaatgat gccagcagtg ccaaagacgt 500

 agactggact gctcggctcc aagacctccg cctgcaggat gctgtcctgg 550

 gtgctgccca tcctgtgcct cctgggctgc cgctcttcct gccctactac 600

 atctgtgttg cagatgagga tgattacagg gactttgtca acctggatca 650

 tgcccacagc cttctgaggg actatcagca gagagaaggc attgccatgg 700

 atcagttgct ttcccaaagc cttcctaatg atggtgatga aaaatatgag 750

 aagaccataa ttaaaagtgg agatcagacg ttttacaaat tcatgaagcg 800

 aattgctgct tgtcaggagc agattttgag gtattcctgg agtggagagc 850

 cactcttttt gacctgccct acatcagaag tcaccgagct cccagcctgc 900

 agccagtgtg gaggccaaag gatatttgag tttcagctta tgccagcact 950

 ggtcagcatg ctcaagagtg ctaatttagg tctttctgtg gaatttggaa 1000

 caattctagt ttacacatgt gagaagagtt gctggccccc aaatcatcag 1050

 actcccatgg aagaattttg tattatacaa gaagacccag atgaattatt 1100

 gtttaagtag agcatttcct tttattaata taaattaaaa caaatgttta 1150

 catccaaaaa aaaaaaaaaa aaaa 1174

<210> 4010
<211> 358
<212> PRT
<213> Homo sapien

<400> 4010
 Met Ala Ala Val Leu Lys Pro Val Leu Leu Gly Leu Arg Asp Ala
   1               5                  10                  15

 Pro Val His Gly Ser Pro Thr Gly Pro Gly Ala Trp Thr Ala Ser
                  20                  25                  30

 Lys Leu Gly Gly Ile Pro Asp Ala Leu Pro Thr Val Ala Ala Pro
                  35                  40                  45

 Arg Pro Val Cys Gln Arg Cys Gly Gln Pro Leu Ala Leu Val Val
                  50                  55                  60

 Gln Val Tyr Cys Pro Leu Glu Gly Ser Pro Phe His Arg Leu Leu
                  65                  70                  75

 His Val Phe Ala Cys Ala Cys Pro Gly Cys Ser Thr Gly Gly Ala
                  80                  85                  90

 Arg Ser Trp Lys Val Phe Arg Ser Gln Cys Leu Gln Val Pro Glu
                  95                 100                 105

 Arg Glu Ala Gln Asp Ala Gln Lys Gln Gly Asn Ser Leu Ala Ala
                 110                 115                 120

 Glu Asp Trp Cys Glu Gly Ala Asp Asp Trp Gly Ser Asp Thr Glu
                 125                 130                 135

 Glu Gly Pro Ser Pro Gln Phe Thr Leu Asp Phe Gly Asn Asp Ala
                 140                 145                 150

 Ser Ser Ala Lys Asp Val Asp Trp Thr Ala Arg Leu Gln Asp Leu
                 155                 160                 165

 Arg Leu Gln Asp Ala Val Leu Gly Ala Ala His Pro Val Pro Pro
                 170                 175                 180

 Gly Leu Pro Leu Phe Leu Pro Tyr Tyr Ile Cys Val Ala Asp Glu
                 185                 190                 195

 Asp Asp Tyr Arg Asp Phe Val Asn Leu Asp His Ala His Ser Leu
                 200                 205                 210

 Leu Arg Asp Tyr Gln Gln Arg Glu Gly Ile Ala Met Asp Gln Leu
                 215                 220                 225

 Leu Ser Gln Ser Leu Pro Asn Asp Gly Asp Glu Lys Tyr Glu Lys
                 230                 235                 240

 Thr Ile Ile Lys Ser Gly Asp Gln Thr Phe Tyr Lys Phe Met Lys
                 245                 250                 255

 Arg Ile Ala Ala Cys Gln Glu Gln Ile Leu Arg Tyr Ser Trp Ser
                 260                 265                 270

 Gly Glu Pro Leu Phe Leu Thr Cys Pro Thr Ser Glu Val Thr Glu
                 275                 280                 285

 Leu Pro Ala Cys Ser Gln Cys Gly Gly Gln Arg Ile Phe Glu Phe
                 290                 295                 300

 Gln Leu Met Pro Ala Leu Val Ser Met Leu Lys Ser Ala Asn Leu
                 305                 310                 315

 Gly Leu Ser Val Glu Phe Gly Thr Ile Leu Val Tyr Thr Cys Glu
                 320                 325                 330

 Lys Ser Cys Trp Pro Pro Asn His Gln Thr Pro Met Glu Glu Phe
                 335                 340                 345

 Cys Ile Ile Gln Glu Asp Pro Asp Glu Leu Leu Phe Lys
                 350                 355

<210> 4011
<211> 1985
<212> DNA
<213> Homo sapien

<400> 4011
 gcaccgcccc cgcccgcaag aaagatggca gtggcctgat ccgggcccgt 50

 tggcggcgtc actgacgctt cgctccggtc ctcggatccc gagcgcgggg 100

 aggcagaccg actgtgagct gcttgtcccc atcctgcggc cgtcctgggg 150

 acacagagcc ctccgtggtg cccggggatt ggattggagc caggacctca 200

 cttcctcctc tgcccctgcc cctgcccctc ccagcacctg gcccacaccc 250

 tgcagcccgc cccatggtct ggccctgggt ggcgatggcg tccaggtggg 300

 gtcccctcat tggcctggct ccgtgctgcc tctggctcct gggggcagtc 350

 cttctgatgg acgcgtctgc acggcctgcc aaccactcgt ccactcgaga 400

 gagagtagcc aacagggagg agaatgagat cctgccccca gaccacctga 450

 acggggtgaa gctggagatg gacgggcacc tcaatcgcgg cttccaccag 500

 gaggtcttcc taggcaagga cctgggtggc tttgatgagg acgcggagcc 550

 gcggcggagc cggaggaagc tgatggtcat cttttccaag gtggatgtga 600

 acactgaccg gaagatcagt gccaaggaga tgcagcgctg gatcatggag 650

 aagacggccg agcacttcca ggaggccatg gaggagagca agacacactt 700

 ccgcgccgtg gaccctgacg gggacggtca cgtgtcttgg gacgagtata 750

 aggtgaagtt tttggcgagt aaaggccata gcgagaagga ggttgccgac 800

 gccatcaggc tcaacgagga actcaaagtg gacgaggaaa cacaggaagt 850

 cctggagaac ctgaaggacc gctggtacca ggcggacagc ccccctgcag 900

 acctgctgct gacggaggag gagttcctgt cgttcctcca ccccgagcac 950

 agccggggaa tgctcaggtt catggtgaag gagatcgtcc gggacctgga 1000

 ccaggacggt gacaagcagc tctctgtgcc cgagttcatc tccctgcccg 1050

 tgggcaccgt ggagaaccag cagggccagg acattgacga caactgggtg 1100

 aaagacagaa aaaaggagtt tgaggagctc attgactcca accacgacgg 1150

 catcgtgacc gccgaggagc tggagagcta catggacccc atgaacgagt 1200

 acaacgcgct gaacgaggcc aagcagatga tcgccgtcgc cgacgagaac 1250

 cagaaccacc acctggagcc cgaggaggtg ctcaagtaca gcgagttctt 1300

 cacgggcagc aagctggtgg actacgcgcg cagcgtgcac gaggagtttt 1350

 gagcgcccgg ccgcgccccg cgccgccccc cacgcaccac cggggcggcc 1400

 tcgcgggtga ctccgggctc cgtggctgtc ccggacccca cctcttccct 1450

 gccgcccgcc accggccgac cgaccgcggc tgccccagtt gatgagcggc 1500

 gtgtcccctc tgcagcgcgc accccggcgg ggctttggct gtgacgcggt 1550

 cggggcgcgg ggctgggctg tggccccgcg gcgccgcctc ctccctggtc 1600

 cctcgaaatc gtggcatctc acttctgaga acgaaatctc gcttcagtca 1650

 ctctgccgaa ggcgctgacg gcatcgcggc cggaacctct gggcccggcc 1700

 cctcccaggg ccgccgctcc gtgggaaaaa acagctcctc catttccttg 1750

 aaaactgaac gattattaaa aatagattaa acttcgctgg aaatgagtag 1800

 ccaggaagtt caggggaggg tgccgggtcc ttcccgggcc tggcgtgtcg 1850

 gagccaccca ggtcccgcag ctgccgctga gaaaatgcaa atatttgttg 1900

 tgacaagaat cacatacatt tactttaaat atagttgcct tttttggtca 1950

 gcttcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1985

<210> 4012
<211> 362
<212> PRT
<213> Homo sapien

<400> 4012
 Met Val Trp Pro Trp Val Ala Met Ala Ser Arg Trp Gly Pro Leu
   1               5                  10                  15

 Ile Gly Leu Ala Pro Cys Cys Leu Trp Leu Leu Gly Ala Val Leu
                  20                  25                  30

 Leu Met Asp Ala Ser Ala Arg Pro Ala Asn His Ser Ser Thr Arg
                  35                  40                  45

 Glu Arg Val Ala Asn Arg Glu Glu Asn Glu Ile Leu Pro Pro Asp
                  50                  55                  60

 His Leu Asn Gly Val Lys Leu Glu Met Asp Gly His Leu Asn Arg
                  65                  70                  75

 Gly Phe His Gln Glu Val Phe Leu Gly Lys Asp Leu Gly Gly Phe
                  80                  85                  90

 Asp Glu Asp Ala Glu Pro Arg Arg Ser Arg Arg Lys Leu Met Val
                  95                 100                 105

 Ile Phe Ser Lys Val Asp Val Asn Thr Asp Arg Lys Ile Ser Ala
                 110                 115                 120

 Lys Glu Met Gln Arg Trp Ile Met Glu Lys Thr Ala Glu His Phe
                 125                 130                 135

 Gln Glu Ala Met Glu Glu Ser Lys Thr His Phe Arg Ala Val Asp
                 140                 145                 150

 Pro Asp Gly Asp Gly His Val Ser Trp Asp Glu Tyr Lys Val Lys
                 155                 160                 165

 Phe Leu Ala Ser Lys Gly His Ser Glu Lys Glu Val Ala Asp Ala
                 170                 175                 180

 Ile Arg Leu Asn Glu Glu Leu Lys Val Asp Glu Glu Thr Gln Glu
                 185                 190                 195

 Val Leu Glu Asn Leu Lys Asp Arg Trp Tyr Gln Ala Asp Ser Pro
                 200                 205                 210

 Pro Ala Asp Leu Leu Leu Thr Glu Glu Glu Phe Leu Ser Phe Leu
                 215                 220                 225

 His Pro Glu His Ser Arg Gly Met Leu Arg Phe Met Val Lys Glu
                 230                 235                 240

 Ile Val Arg Asp Leu Asp Gln Asp Gly Asp Lys Gln Leu Ser Val
                 245                 250                 255

 Pro Glu Phe Ile Ser Leu Pro Val Gly Thr Val Glu Asn Gln Gln
                 260                 265                 270

 Gly Gln Asp Ile Asp Asp Asn Trp Val Lys Asp Arg Lys Lys Glu
                 275                 280                 285

 Phe Glu Glu Leu Ile Asp Ser Asn His Asp Gly Ile Val Thr Ala
                 290                 295                 300

 Glu Glu Leu Glu Ser Tyr Met Asp Pro Met Asn Glu Tyr Asn Ala
                 305                 310                 315

 Leu Asn Glu Ala Lys Gln Met Ile Ala Val Ala Asp Glu Asn Gln
                 320                 325                 330

 Asn His His Leu Glu Pro Glu Glu Val Leu Lys Tyr Ser Glu Phe
                 335                 340                 345

 Phe Thr Gly Ser Lys Leu Val Asp Tyr Ala Arg Ser Val His Glu
                 350                 355                 360

 Glu Phe


<210> 4013
<211> 1523
<212> DNA
<213> Homo sapien

<400> 4013
 ggcacgaggc ttgcatcaac aatacttcag tcatgatgtt taaaaagggg 50

 agctttgaaa ttggaggaac catacatcca gttgcaatta agtataaccc 100

 tcagttcggt gatgcatttt ggaacagtag taaatacaac atggtgagct 150

 acccttcgaa tgatgaccag ctgggccatc gtctgtgacg tgtggtacat 200

 gccccccatg accagagagg aaggagaaga tgcagtccag tttgctaaca 250

 gggttaagtc tgctattgct atacaaggag gcctgactga acttccctgg 300

 gatggaggac taaagagagc aaaggtgaag gacatcttta aggaagagca 350

 gcagaaaaat tacagcaaga tgattgtggg caatggatct ctcagctaag 400

 aggacggatg acagccttta gatctagaac tagcccttag aaatggaatg 450

 gcttttttgt tttgttttgt tttattgttt tgtttttatt attgttaatc 500

 ttttctacag aatgattgtc tctacctctt tatgccagag gcagaaccta 550

 caggtgccct ttttggcttt tgttgttgtt gtaacattag ccccatggat 600

 tgtaaggtgg tttactgagt taaaacagat tctgcttttg taaaatgatg 650

 gcatcactgt ggactgaatg aaatatttgt atagaaaaaa gtgcttgaaa 700

 agtgtgtttg gaactcatcg atagggtaat tctccaaaaa tgcccaaact 750

 ctctttctgt aattagcctt gccactttct tcagtcactt aaatggtgag 800

 attacacatc agtgcaagat gaccattatg gttatggtct actgcaaggt 850

 tgaaaggaaa aatggaggat tgtatttagg aaaagggaca actttgtggc 900

 cacctgctct gaaagtcaaa aggaaatgta aattagtgtc attagtgtgt 950

 tggaagagaa atactattca gtaagcttcg ccaaagaaaa gtgagtcaaa 1000

 gttaatgtgt gtgtgcattt atatgtaggc agctcgtaga ccacatttta 1050

 gccagcaact ggtaacaaag agcttagttt tccttgtttg aatgctgtag 1100

 atctgtacct agtacccctc ccatctactg atttgtttgt ttttgtaacc 1150

 aaacacattt tcagatagaa ggagccttaa aaaaaaaaaa atcacattga 1200

 gtaacttcag tatgaatgaa tgagagtgtg tggagctacc cctcaccctc 1250

 cacccctttg tgctttttat tcccgaattt tcccagtctc ttaaacagaa 1300

 aaatgactga tataattatc ttttggaaac tgagccttaa ttttttttag 1350

 agggggaaat aagttttccc caactcacac agcataagca atgtttgaca 1400

 gcaatataat gccgttgtaa actactgaga gtattgtatc tgttctggta 1450

 accatgtaca gaatgtgaaa ctgtcttatg aatataaata aattctatat 1500

 ttctaaaaaa aaaaaaaaaa aaa 1523

<210> 4014
<211> 78
<212> PRT
<213> Homo sapien

<400> 4014
 Met Thr Ser Trp Ala Ile Val Cys Asp Val Trp Tyr Met Pro Pro
   1               5                  10                  15

 Met Thr Arg Glu Glu Gly Glu Asp Ala Val Gln Phe Ala Asn Arg
                  20                  25                  30

 Val Lys Ser Ala Ile Ala Ile Gln Gly Gly Leu Thr Glu Leu Pro
                  35                  40                  45

 Trp Asp Gly Gly Leu Lys Arg Ala Lys Val Lys Asp Ile Phe Lys
                  50                  55                  60

 Glu Glu Gln Gln Lys Asn Tyr Ser Lys Met Ile Val Gly Asn Gly
                  65                  70                  75

 Ser Leu Ser


<210> 4015
<211> 8311
<212> DNA
<213> Homo sapien

<400> 4015
 gcggccgcga ccccgacggc ttcctgcgcg tggagcgcgt cgcggcgctc 50

 ggactgcgct tcggccaggg cgaggaggtg gaaaaacttg tgaaatattt 100

 ggatcccaac gacctgggga gaatcaactt caaggacttt tgccgggggg 150

 tgttcgccat gaaagggtgc gaggagctgc tgaaggatgt gctgtcggtg 200

 gagagcgcgg ggacgctgcc gtgcgcgcca gagatcccag actgcgtgga 250

 gcagggcagc gaggtcacag gccccacctt tgctgatggc gagctcatcc 300

 ccagggaacc cggctttttt cccgaggacg aggaggaggc tatgacgctg 350

 gcgccacctg agggccccca ggagttgtac acagacagcc ccatggagag 400

 cactcagagc ctggaggggt ctgtcgggag tcctgccgag aaggacgggg 450

 gacttggggg cctgtttctg ccagaagaca agtccctggt ccacactcca 500

 tccatgacga cctcagacct ttctacacac tccaccacct cgctcatcag 550

 caatgaggag cagtttgaag actatgggga gggtgacgat gtggactgtg 600

 cccccagcag cccttgcccc gatgatgaga ccaggaccaa cgtctactcg 650

 gacctggggt cttcggtgtc ttccagtgcg gggcagacgc ctaggaaaat 700

 gcggcacgtg tacaacagcg aattgctaga tgtttactgc tctcaatgct 750

 gcaagaaaat caacctgctc aatgacttgg aagcccgact gaaaaacctg 800

 aaggccaaca gccccaaccg aaagatctcc agcacggcct ttggacggca 850

 gctcatgcac agcagcaact tcagcagcag caatggcagc accgaagacc 900

 tgttccggga cagcattgac tcttgcgaca atgacatcac agagaaggta 950

 agcttcctgg aaaagaaggt gacagagctg gagaatgaca gcctgaccaa 1000

 tggggacctg aagagcaagc tgaagcaaga gaacacacag ctggtgcaca 1050

 gggtgcatga gctggaggag atggtgaagg atcaggagac cacggccgag 1100

 caggctctgg aggaggaggc gcggcgccac cgcgaggcct acggcaagct 1150

 ggagagggag aaggctaccg aggtggagct gctcaatgcc agggtgcagc 1200

 agttggagga agaaaataca gagcttagaa caacagtgac tcggctcaag 1250

 tctcaaacag agaaactgga tgaggagcgg cagcgcatgt ctgaccgtct 1300

 ggaggacacc agcctgcggc tcaaagatga gatggacctg tacaagcgca 1350

 tgatggacaa gctgcgacag aaccgccttg agttccagaa ggagcgggag 1400

 gcgacgcagg agctcatcga ggacttgcgg aaggagctgg agcacctgca 1450

 gatgtacaag ctggactgcg agcggccagg caggggccgc agtgcctcct 1500

 ctggcctagg cgagttcaat gccagggccc gcgaggtgga gctcgagcac 1550

 gaggtcaagc ggctcaagca ggagaattat aagctgcggg atcagaacga 1600

 cgacttgaat gggcagattt tgagcctcag cctctacgaa gcaaaaaacc 1650

 tctttgctgc ccagactaaa gcccagtctc tggctgcgga gatagacacc 1700

 gcctcgcgcg atgagctaat ggaagccctg aaggagcagg aggagatcaa 1750

 cttccggctg aggcagtaca tggacaagat tatcctcgcc atcctggacc 1800

 acaatccctc catcctcgag atcaaacact aaggcacggg gctggctgca 1850

 gagcagcctt aggaccctgg gaccaagggc agaccctgcc caaggatgca 1900

 ggcctaagcc gggcctcaca ctcacactgt aaatgtctct ctggccacca 1950

 tgcgttacgt gtacccgtgt atatgtgggg aggctgtgca cacgagcgag 2000

 gggtgagtgg ccgtggctgt gggcagcatc cacacggtta gccgtgcatg 2050

 cactttgtgg cccctttgca aggggcagag ggtactggaa gtgggaggag 2100

 gcaaggtctg ctatcaggag ttactgtaaa aacaagaact ggaagctcgt 2150

 gtttccggta ctgggtaaaa tgattctacc tctggggata aggattcaca 2200

 ttcgctctag tacgatgggc tctttcaccc cactcctagt ccccttggga 2250

 gtgggagcaa aattgtgatc tttcctagga gtttgaatgc cccatatttg 2300

 tgtcctcgcc agctctttgg ccacctttca agccccagtg ttcaagctca 2350

 gagaggatga aggggcatct ggagggtcca tgagatgggg ccctcaccaa 2400

 atgccttggc caccggccag cagccctctg tgatgtgtgt gcagagtgaa 2450

 cagaggactc aggtttcata gcagctagtg cggggcatcc tcatcctgta 2500

 cctatagagt tcgtgcactc ccccatccat gctacctacc tccccgtttc 2550

 tgtttcagtt ttaagacaat gaagcagcat tcactgcgtc attgtaacat 2600

 gaagggataa aaatgaagga gaaggagggt ttgggatggg tgtctaaggc 2650

 aggagttgac atcgggcaac caaagaaatg agttttgggg aggaacacaa 2700

 ctcccatccc agtcagtttc cttcccatgg ctgcatctta agatggatgc 2750

 acggagaaac cgtctgcctg gctccctgtc ttcattctcc acgcagcctg 2800

 gtgatggcag gcctgggttt ggatttcaga atcctagctc cgggctccac 2850

 tcgtgtggca gcaagactgc ttcgttccag cgtttagaaa cacacctgta 2900

 tttgattctc agccagggga gcactcgctg cactggtggg aggcggttgg 2950

 gaaagttgca ggaaaacctt agtcttccat ccttctgacc catggtggaa 3000

 attcacacca tggattttta atggatcttt gttctaggca gctgggaata 3050

 gacatggtac ttaccttaga gttttccaat ttatctcaat tttatatggc 3100

 ttgtgattca ttttcttaat ccaaatatat ataaacgtgt ctggtcttat 3150

 tcttccccct gcagtttctt gctttcttca gcacatctta tagtatgaga 3200

 aggaaggttt gggcatgttg ggaagggcgg tggaggggga gttgcagaaa 3250

 gagagggcag tgagggtgag gagaggggat ctggggactt gggtgtgaca 3300

 cctgcttgac agaggcaggg ctgtggccag gaccaacctt caattccatt 3350

 ccaatcagcc tttgcatttg ttggatctcg tggcttcttt ttaatctttt 3400

 gttggggatt agtttcatgc tgcacataat ggggttgcac tggtctgacc 3450

 caggactttg gagccaccca cactgggaag actaggctag gcagtcggtc 3500

 ttctaggagt ttctcagccc cttaggacgc gggtctcctt gggctccccc 3550

 aagggttctg cgaagaggca gtggaagaag gcatgaggag agggtctctt 3600

 gagaatttgc caataggaag gagtggccac ggctgaaagg aacaagacag 3650

 atcctgacat agctttggcc tgggtgttag gtcagaagga gtactggtgc 3700

 gtgggggcct taccccaggg ttgagtattt tatctgtaaa atgttatctg 3750

 ccctttggct gcattggaat ttcagagaag gctgcagagg cctgggttac 3800

 acagcctgag tcacaacgtg ggaaggaatc tctgccacgg gaaaggtggg 3850

 cggaagcagc tggcagcctg gggcgtgctt caggctcctc cctctaaggg 3900

 gcgccatggg aacaggctcc ggagggagcc ggcgtctgaa aggcccccgg 3950

 gacctgctgc agtgccagag gggcctctgg agcaggcctg gcttttaaat 4000

 ggggggctga attccagctc acacacacct caagtccaac cttactttct 4050

 tcagccagaa tacatttctt gtaaaacctg gcttgttgct tggcttttaa 4100

 agatggtgta tgtttgtaaa aatattcttc tgggctcaaa agctagcttg 4150

 agggggcaga tgccccaggt gtcccagctc cacagcccct ggcagatccc 4200

 agaccccttg gtggcaggtc ccagagccta ggtggtagga gcttgatctt 4250

 tgtttctgcc cttacccctc agtagtgggg ctgcgaggta gtagacagga 4300

 tgcccagtta agtttgaatt tcagatagaa aataatttta gaataaatat 4350

 gttctatcta atacatggga cagatgttat ttttagagat aggatcttgc 4400

 tctgttgccc aggctggagt gtagtggtat gatcatagct caccacaacc 4450

 ttgaactccc aggctcaggc gatcctcccg ccttggctgc ctgagtagct 4500

 gggactgcag gcatgcacca ccacgcccag ctaatttttc ttattttttg 4550

 tggagacagg gtctcactgt gttgcctcac tcgagctgct gacctcaagt 4600

 gatcctcccg cctcagcctg ccaaagcact gggattacag gcatgagcca 4650

 ccatgcctgg ccaggacata tttgaaatgg ggagatttta aaaattctga 4700

 tgattagact gaatcctcag acgttctggt ttgattgttg tgggtgtagc 4750

 ccaggcatgg gattttttaa agagctgctc aggtaattcc aatttaattg 4800

 cgtgtcctac ttgggttttt tgtttgtttt tattgttttt gctaaacctg 4850

 gcaaccctac cgagtaggga ttagcagtaa cctatctgaa atttagaggt 4900

 gttttggggg tggggcgagg gtttctgtag tagactcaga ttttacatgg 4950

 ccctgagctg cccttgcgtt cagttggaag ccacgcaaaa tgaactgaac 5000

 caggagtgag cttcgtgtac attatctatt agaaaatgaa gtaccttctg 5050

 gttcagctag tccctgtgcg ttgagaggct ttaagaaact tctagtaaaa 5100

 atgttttttt cttttagctt tgaattggcc agagtttatc ctagattatt 5150

 ttattttaaa ttggtagaat tctttgcgaa ctgtcacaga gaaattcctt 5200

 ttcatgactt tatttctgac ctattaaaac atgaacaggc caggcatggt 5250

 ggctcacgcc tgtaatccta gcacttggga ggcagtggcg ggcggatcac 5300

 ttgagctcag gagtcctaaa ccagcctggg caacatagtg ataccttgtc 5350

 tctaccaaaa gttaaaaaaa aaaaaaaaaa agctcaagaa cctgcacgag 5400

 ggcctaaaac agtgggctca gctttggctg tgcattggaa tcacctgggg 5450

 agatttgtaa gcttctgctg tctgggctga acccccagag gttcggattg 5500

 aattggtgtg gggtgtggtc caggcatcga gatgtgtaaa gacctcccca 5550

 ggtgatgata tgcagtccga ggttgagact gccctgtcct gcaaggtcgt 5600

 tggccagagg tagaggaaac tggtcaaagt ggctgttggg cttgtcaagc 5650

 ccgtggctga atgacagtga gctctcttgc tgggagggtt ccttttcctg 5700

 ttgttgaatg gtcctggcct gcaggatggg aggccagatg ccttcaggag 5750

 ctggtggatc cagctgttct caccagcctg gaggttagca gaccagagtg 5800

 ggtgggcagg accttggcct ggtgcccctg gaatcagtgg gtggcatgtg 5850

 ttgggatata ctggctacag gctcatctca aagagcaggt agaacagagt 5900

 cagcagggaa ctgacaggtg gggctgtccc cctgaaagca gccgcagaaa 5950

 cagctgccac ctatttgcat agctgagcag gaggacatac tgtctttgtg 6000

 ggttttgctt ctggtctgtt tcctgactgg gttgataaag ggagtcccag 6050

 ctcgttccct gttagccaaa ccagcatcct actcacacac cggacactcc 6100

 aggtgctagt ccactggtgc tggtgttcag gggagttggg gggggggggc 6150

 gcggggacag aagcgcgggt tcttggttcc aatgagggac ttagcagaag 6200

 cctccagggg ccagcagggc caggtgaaac tgggagaaat gaagccctct 6250

 gtgtcctgtg tgtgtggtgg ggtttaatgc attagcaaat ttaaacttaa 6300

 aaactaactc taggccgggc acggtggctc acacctgtaa tcccagcact 6350

 ttgggaggcc aaggcaggtg gattgcctga gctcaggagt tcgagaccag 6400

 cctggacaac atggtgaaac tcttgtcttt atttttttaa aaaaacaaaa 6450

 agtaactttc gatgtgatca taccaggaaa gttttgcgtg gtcaccatgc 6500

 caagaaaatg actttggttg cccagcagat ccacagcgac tctttctcaa 6550

 gggctactgt ggattctaga ttgaggaaag gggccactta ggactcagtg 6600

 ctggtatcct ccacagtcct ttctcccaga ctctggccct ccctttggga 6650

 cccaggaaat cccctctagg gtgacgctgc tggctaggaa gactgaggtc 6700

 tgctgcgcca aggggcctca agttagaagg gccatgccgt tcagtggatg 6750

 actttgagcg ctgatcctag ggacctgcca ggtcctcact tcctgccctg 6800

 ggtgcacaca tgaatggggc agccagcagg aagcgggaga ggctggaacc 6850

 aggagcctgc cctacctgca tggcaggaca actctgaggc ccttctgcca 6900

 tattctctgc tacccaccag agaaaatagg ctgccttcta gaaagatttg 6950

 tttctaaaag cgtagaccct ggggaagtat aatgtcacca tgctcaccag 7000

 gcgaggtttc ccatatgacc tccctgcccc gacctcgtag gttgctcctt 7050

 tccccatctg taaggtagag atgtctgccc cggagctacc agctggggat 7100

 ggcatccagg ccatgtctcc tgcaggatcc aagtgctgtt gtccccaggg 7150

 tgaccctgcc tcctgctggg gcccatccgc tttgctgtgc tgcacaggct 7200

 gttttcatct gcatggtttg gggtctttgt ccttgtgcct tttcttcccc 7250

 atcgccactg tacaggattt tccacattgc ccactgcctc cttttctaca 7300

 tcgtctcatc tccctggcct ttcccgagcc ctgtaaatgt gtactttttc 7350

 aacgtgcctc ccccaggtga ggccagctct cccgggcaca ttcgtccaca 7400

 aggatcaggc cccacttacc cttggctcgc tcagcctgta gacttggtaa 7450

 ctttgtacag aatctttcat tattgtctta agcatggggg gctaggaccc 7500

 acttagtccc tcctccagcc tgcagctaat ttaggagcct tgcattccag 7550

 aaaagggcaa ctttgtgtaa agcagcttct cccacagagc tttccctgca 7600

 ttgttagtga tgtcgggcaa agcatcactc tttaacctgg ggcattggcc 7650

 ccagcaggga tatcatggga ccgcagccgc tccgtgcact gtctctgccc 7700

 ccagaggaag ccctgtccat ggttcctggt gcacggccac aggcctgcct 7750

 tgaggccacc acatctggtg tctagaacag ctgcgggccc cacttgggca 7800

 gaaggaagag gtgctagctg ctgcccctgc ctgctgtgaa cacctgccca 7850

 gcccttcctt gtctgctgag gtgctcagac cagagtgcca ttaaatacca 7900

 actgatgtca cggagcggac ggtgcattgc caaggactca cagctgtggg 7950

 ctcccttcca gctcctccca ctttcttggc tgggtcttct gaggcctacg 8000

 tggaatgaac tacacatgtg gcctcatgcc caagggtttg ttagatggcc 8050

 tctgactctg tgggattcaa cttgactttt ttgccccagg aggctctgtc 8100

 tggaaacagg cttagcttta gtgctggggt gggacctgcc ctgtgggccc 8150

 cagggagggg acagtggggg tgaggccctg aggctgtcca gggtctgagc 8200

 tctttgcctc caacctgctt ctgccccaaa aggaacaggc tgttggtggc 8250

 aggctcctcc cggggagctg tactgtacag accaaggtgt aaataaacag 8300

 tttgctcttc t 8311

<210> 4016
<211> 1677
<212> DNA
<213> Homo sapien

<400> 4016
 ctgagatcag acacacttgg gccgggttgg gaggaactgg caggaaaagg 50

 actgaaccct taatgtcagg cggttttgaa gcacctgggg caagctatgg 100

 aaatccccac aggaaggctc acgcagtctc ttaggcggct gccctccacc 150

 tgccacgttc tttttgattg actaaaaaac gctgaatgaa gaacgaagtc 200

 gcgtggaaac cctcgccgcg cgcctgcagc ggacagcgca gcccgggagg 250

 ttcggctgcg gacttgcgcc cgggggctgc gctgcgagcg gccacgcatg 300

 gcggctggac ccgggcggcc gcaagggctt ggctgggccg cgggaggcgg 350

 gaggttcttc gtcctcccga gccatctccc tgaactgaca agcaggactc 400

 ccgggtccag ggggcacagg gcccggggcg gtgacccggc ggatcgggct 450

 gccggaggag cccactgtaa atgccgcaac tggccccaaa cactgcgttc 500

 ctggactgca ccagcagctc ctggcgcggc cgcagagttg gtggatattt 550

 tccaaggggg aaaaaaatct tttaaatgcc atctgtttac tttaaaaatg 600

 ttgattactt aagaaaaacg aatggatgtc tgggcaaagg tatggacgtc 650

 acaattattt tgaaggcgtc ctttttaact ttaaacagac cacgccagga 700

 ggagactgct gacccagagc gcattaccta aaatctggta cccagagtgc 750

 acccttcgcc ctcgttggag ttctctcctc tctgccaagc tttgctccgt 800

 gccagaggtg tgctccattg tacctccgct ctgtccctgc agtcaggcaa 850

 ccaattggag aagagtataa atagtaatta accagggaga gttgtaattc 900

 agaaacctag ttaaaacaag tcctcaaaaa ctagagaata tgagagtggg 950

 gagacatttt gaaggcatta agaacaaaaa acgatgggga cgaatggttg 1000

 agtctgagga tcagcatcgt aatctgttag agaacgaggt cgtggctgtg 1050

 tctgtgagtc gttaatgggt ttaatcggtt gatacacagc ctgctagtgg 1100

 cctaaccagt aacccagggc ctggcagatt tgcatgacat ctcggagttt 1150

 gattgctctt ccttccactt ggcaaaagga gacaccatca gccggatcag 1200

 gaggggtcat ggtgagatgg aacccaccga ggtggtgtac agagctggcg 1250

 ctgccaatgg ccagagtggc agcctttcta cctccttaac cctgcaaaaa 1300

 tcaaacgtgc tagtacgcac tgtccatcca cactggaact ccagttggtt 1350

 ttagtctgcg atgatgactc ttctgggttg acttttccag ttcattatgc 1400

 agccctcttg aagcaggcct cccaaactta gcagacacca atgagaacct 1450

 cacagagagg ctcatcaagc aggctggtga aactgggtgt tacttcctgt 1500

 tccatgggta ccccatagtg tttgggaaac accgggctgt ggttcaggag 1550

 aatttcacat atgctaagat ggagaaagaa cctgcccttt acatttaggc 1600

 ttgggatgtt aatttaaagt ttgaatgacc aaaaattaaa tctgtaactt 1650

 ttaaaaaaaa aaaaaaaaaa aaaaaaa 1677

<210> 4017
<211> 43
<212> PRT
<213> Homo sapien

<400> 4017
 Glu Ile Arg His Thr Trp Ala Gly Leu Gly Gly Thr Gly Arg Lys
   1               5                  10                  15

 Arg Thr Glu Pro Leu Met Ser Gly Gly Phe Glu Ala Pro Gly Ala
                  20                  25                  30

 Ser Tyr Gly Asn Pro His Arg Lys Ala His Ala Val Ser
                  35                  40

<210> 4018
<211> 2061
<212> DNA
<213> Homo sapien

<400> 4018
 ggaggctcat cataatcgtt agctattgtc accgattgta ttgttatgac 50

 ttctaccacc accactcccc ctcctcctgg gatggtgatt ccagggccag 100

 gcggcaggct ataactagcg cccttccagg tggaacccgc cagagccccg 150

 aggcagccta ggattttctg agatcagaca cacttgggcc gggttgggag 200

 gaactggcag gaaaaggact gaacccttaa tgtcaggcgg ttttgaagca 250

 cctggggcaa gctatggaaa tccccacagg aaggctcacg cagtctctta 300

 ggcggctgcc ctccacctgc cacgttcttt ttgattgact aaaaaacgct 350

 gaatgaagaa cgaagtcgcg tggaaaccct cgccgcgcgc ctgcagcgga 400

 cagcgcagcc cgggaggttc ggctgcggac ttgcgcccgg gggctgcgct 450

 gcgagcggcc acgcatggcg gctggacccg ggcggccgca agggcttggc 500

 tgggccgcgg gaggcgggag gttcttcgtc ctcccgagcc atctccctga 550

 actgacaagc aggactcccg ggtccagggg gcacagggcc cggggcggtg 600

 acccggcgga tcgggctgcc ggaggagccc actgtaaatg ccgcaactgg 650

 ccccaaacac tgcgttcctg gactgcacca gcagctcctg gcgcggccgc 700

 agagttggtg gatattttcc aagggggaaa aaaatctttt aaatgccatc 750

 tgtttacttt aaaaatgttg attacttaag aaaaacgaat ggatgtctgg 800

 gcaaaggtat ggacgtcaca attattttga aggcgtcctt tttaacttta 850

 aacagaccac gccaggagga gactgctgac ccagagcgca ttacctaaaa 900

 tctggtaccc agagtgcacc cttcgccctc gtggagttct ctcctctctg 950

 ccaagcttgc tccgtgccag aggtgtgctc cattgtacct ccgctctgtc 1000

 cctgcagtca ggcaaccaat tggagaagag tataaatagt aattaaccag 1050

 ggagagttgt aattcagaaa cctagttaaa acaagtcctc aaaaactaga 1100

 gaatatgaga gtggggagac attttgaagg cattaagaac aaaaaacgat 1150

 ggggacgaat ggttgagtct gaggatcagc atcgtaatct gttagagaac 1200

 gaggtcgtgg ctgtgtctgt gagtcgttaa tgggtttaat cggttgatac 1250

 acagcctgct agtggcctaa ccagtaaccc agggcctggc agatttgcat 1300

 gacatctcgg agtttgattg ctcttccttc cacttggcaa aaggagacac 1350

 catcagccgg atcaggaggg gtcatggtga gatggaaccc accgaggtgg 1400

 tgtacagagc tggcgctgcc aatggccaga gtggcagcct ttctacctcc 1450

 ttaaccctgc aaaaatcaaa cgtgctagta cgcactgtcc atccacactg 1500

 gaactccagt tggttttagt ctgcgatgat gactcttctg ggttgacttt 1550

 tccagttcat tatgcagccc tcttgaagca ggcctcccaa acttagcaga 1600

 caccaatgag aacctcacag agaggctcat caagcaggct ggtgaaactg 1650

 ggtgttactt cctgttccat gggtacccca tagtgtttgg gaaacaccgg 1700

 gctgtggttc aggagaattt cacatatgct aagatggaga aagaacctgc 1750

 cctttacatt taggcttggg atgttaattt aaagtttgaa tgaccaaaaa 1800

 ttaaatctgt aacttttaaa gtttctcttt gtgattttac ttaagtgttg 1850

 gtagatattc ttaaattgta atgacctcag tttgggaatt aagttagcca 1900

 aatattgtgt aattattgtt tgttatacaa aaatatgcct tagactgtac 1950

 agcggcagaa actccctcta ccacctcggt ccccctttcc attctgcgtt 2000

 atacaaaata agctgacacg ttaatgctgt ggcccacatt aaacaaagta 2050

 taccgtaaaa a 2061

<210> 4019
<211> 52
<212> PRT
<213> Homo sapien

<400> 4019
 Arg Leu Ile Ile Ile Val Ser Tyr Cys His Arg Leu Tyr Cys Tyr
   1               5                  10                  15

 Asp Phe Tyr His His His Ser Pro Ser Ser Trp Asp Gly Asp Ser
                  20                  25                  30

 Arg Ala Arg Arg Gln Ala Ile Thr Ser Ala Leu Pro Gly Gly Thr
                  35                  40                  45

 Arg Gln Ser Pro Glu Ala Ala
                  50

<210> 4020
<211> 3059
<212> DNA
<213> Homo sapien

<400> 4020
 gttcggtggt gtcccggtgc agccacgcga gagtagaagg gtggaaaggg 50

 gaggtgccca gtgaaatgga gcctgtcccg tgcactttcg ggcatttcga 100

 gcatcttgtg ggctctccca agtcgcggcc cctcctctga gagccacagt 150

 caggtctgtc ctcaggggtc gaggcggctg cgctggggcc tcggcccggg 200

 aggaggcggg gggcacggcc tttccatttt ccctgctccc ctctgcagaa 250

 gcctcatagg gcccggcgcg gcggctcacg cctgtcattc ccagcgcttt 300

 gggcggattg ggtaggagga ttacttgagg ccaggagttc aagaccaggc 350

 agggcaacat agggagaccc cccccccaac catctctaat ggaaaaaaaa 400

 aaaaaagtct ccacatccag cgttgtgcct tttctctata aggaacagca 450

 tctctgcctt cctgttcacg gtgaccttcg cttggtgtcc tcctggcctc 500

 agcaacctga caattctgtc gtgtcccgag agatggctaa tgaatggcgc 550

 ttgatgacag atgagtaatg cctgttgctg aaagattgac gatcatcttt 600

 ctcaagatgt tttctgtctt catgagtcaa aatttgaaga ggaaaggatg 650

 gtggctgggt ggttgacaaa ttactctcag gactcagtga cctttgagga 700

 tgtggctgtg gacttcaccc aggaggagtg gactttgctg gatcaaactc 750

 agagaaactt atacagagat gtgatgctgg agaactataa gaatctagtt 800

 gcagtagatt gggagagtca tattaatacc aaatggtcag cacctcagca 850

 gaattttttg caggggaaaa catccagtgt ggtggaaatg gagagaaacc 900

 attttggaga ggaactgttt gactttaacc aatgtgaaaa agccttgagt 950

 gaacactcat gccttaagac tcacaggaga acttacttta gaaagaaaac 1000

 ctgtgagtgt aatcaatgtg aaaaagcctt cagaaaaccc tctatcttta 1050

 ctttacacaa gaaaactgat atcggagagg aacttcctaa ctgtaatcaa 1100

 tgtgaaacag ccttcagcca acatctacat cttgtttgca agaaaactag 1150

 ccaaaatcta catcttgttt gcaagaaaac tcacactcaa gagaaaccat 1200

 ataaatgcag tgactgtgaa aaaggcttac cttcctcctc acacctcaga 1250

 gaatgtgtaa gaatttatgg tggagagaga ccatatactc ataaggagta 1300

 tgtcgaaacc ttttctcatt ctacagccct ttttgtacac atgcaaactc 1350

 aagatggaga aaaattctat gaatgtaaag catgtgggaa acccttcact 1400

 gagtcgtcat atcttactca acatttaaga actcatagta gagtgttacc 1450

 tatagaacat aagaaatttg gcaaagcctt tgctttttcc ccagatcttg 1500

 ctaaacatat aagacttaga actagaggaa aacactatgt ttgtaatgaa 1550

 tgtggcaaag aatttacttg tttctcaaaa ctcaacattc acataagggt 1600

 tcacactgga gaaaaaccgt atgagtgcaa caaatgtggg aaagccttca 1650

 ctgattcatc aggtcttata aaacacaggc gaactcacac tggagaaaag 1700

 ccttatgaat gtaaggaatg tgggaaagct tttgctaact cttcacatct 1750

 tactgtacat atgagaactc acactggtga gaagccttat caatgtaagg 1800

 aatgtggaaa agcctttatt aattcctctt cctttaaaag tcacatgcag 1850

 actcatcctg gtgtaaaacc ctatgactgt caacagtgtg ggaaagcctt 1900

 cattcgatcc tcatttctta ttcgacattt gagaagtcac agtgcagaaa 1950

 ggccttttga atgtgaggaa tgtgggaaag cctttagata ctcctcgcac 2000

 cttagtcaac ataaaagaat acatacaggg gagaggccat ataaatgtca 2050

 aaagtgtggg caagccttca gtatctcatc aggccttaca gtacacatga 2100

 gaactcacac tggtgaacgg ccctttgaat gtcaggaatg tgggaaagcc 2150

 tttactcggt ccacatatct tattcgacat ctaagaagtc atagtgtgga 2200

 gaaaccatat aaggaatgtg ggcaaacctt tagtaattcc tcatgcctta 2250

 ctgaatgtgt gtgaattggg gctgatactt ggaaagaatg tggtaaagcc 2300

 actacttcct cacacttact gaacatgtac tcattcatag tggcaatgta 2350

 cacagtcata aggaatgtgg gaagccttcc ttggtgtctc agatcttaac 2400

 aattccaata gaagagaaga catatgaatg taaggaatgt gggaaaatct 2450

 tggctccttc cataggcctt actattcatg tgtctgtgca tcctaggaaa 2500

 caaactgaac gtaggaaacc tgtcgatgct tacatcttac tgagtctgtt 2550

 tgaactcatg ctggagagaa atgctatgaa tgtgaggaag gtggaaaagc 2600

 tttcattatt ttcctcgggc cttactgagc ttgtgagcac attggatata 2650

 aatgcacgtc ctctggctgt aaggaatgtg ttgaaacctt tcactctgcc 2700

 ttatacctta atattcagct gtgatctcac aagtgtgaaa aatcttatga 2750

 atgtaaaatg tgtggagatt cttctttgtt tttagcttcc actttgggaa 2800

 catgtcaaag cacacattga gaagtcccat gagtgaaaga gatgttggaa 2850

 agcccttgaa cttggtcgtt aggaaacatc cacactgaag aggaacctga 2900

 ctgtatggaa ggtcaaaaag gctgtattaa tttacatgca aaaagtcaca 2950

 ctagaggaat gccatatcag aatgcttttg gtaaatatac atgttttaaa 3000

 gaggttatat atcattaata aaaatatcta gctggtctga aaaaaaaaaa 3050

 aaaaaaaaa 3059

<210> 4021
<211> 538
<212> PRT
<213> Homo sapien

<400> 4021
 Met Val Ala Gly Trp Leu Thr Asn Tyr Ser Gln Asp Ser Val Thr
   1               5                  10                  15

 Phe Glu Asp Val Ala Val Asp Phe Thr Gln Glu Glu Trp Thr Leu
                  20                  25                  30

 Leu Asp Gln Thr Gln Arg Asn Leu Tyr Arg Asp Val Met Leu Glu
                  35                  40                  45

 Asn Tyr Lys Asn Leu Val Ala Val Asp Trp Glu Ser His Ile Asn
                  50                  55                  60

 Thr Lys Trp Ser Ala Pro Gln Gln Asn Phe Leu Gln Gly Lys Thr
                  65                  70                  75

 Ser Ser Val Val Glu Met Glu Arg Asn His Phe Gly Glu Glu Leu
                  80                  85                  90

 Phe Asp Phe Asn Gln Cys Glu Lys Ala Leu Ser Glu His Ser Cys
                  95                 100                 105

 Leu Lys Thr His Arg Arg Thr Tyr Phe Arg Lys Lys Thr Cys Glu
                 110                 115                 120

 Cys Asn Gln Cys Glu Lys Ala Phe Arg Lys Pro Ser Ile Phe Thr
                 125                 130                 135

 Leu His Lys Lys Thr Asp Ile Gly Glu Glu Leu Pro Asn Cys Asn
                 140                 145                 150

 Gln Cys Glu Thr Ala Phe Ser Gln His Leu His Leu Val Cys Lys
                 155                 160                 165

 Lys Thr Ser Gln Asn Leu His Leu Val Cys Lys Lys Thr His Thr
                 170                 175                 180

 Gln Glu Lys Pro Tyr Lys Cys Ser Asp Cys Glu Lys Gly Leu Pro
                 185                 190                 195

 Ser Ser Ser His Leu Arg Glu Cys Val Arg Ile Tyr Gly Gly Glu
                 200                 205                 210

 Arg Pro Tyr Thr His Lys Glu Tyr Val Glu Thr Phe Ser His Ser
                 215                 220                 225

 Thr Ala Leu Phe Val His Met Gln Thr Gln Asp Gly Glu Lys Phe
                 230                 235                 240

 Tyr Glu Cys Lys Ala Cys Gly Lys Pro Phe Thr Glu Ser Ser Tyr
                 245                 250                 255

 Leu Thr Gln His Leu Arg Thr His Ser Arg Val Leu Pro Ile Glu
                 260                 265                 270

 His Lys Lys Phe Gly Lys Ala Phe Ala Phe Ser Pro Asp Leu Ala
                 275                 280                 285

 Lys His Ile Arg Leu Arg Thr Arg Gly Lys His Tyr Val Cys Asn
                 290                 295                 300

 Glu Cys Gly Lys Glu Phe Thr Cys Phe Ser Lys Leu Asn Ile His
                 305                 310                 315

 Ile Arg Val His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Lys Cys
                 320                 325                 330

 Gly Lys Ala Phe Thr Asp Ser Ser Gly Leu Ile Lys His Arg Arg
                 335                 340                 345

 Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys
                 350                 355                 360

 Ala Phe Ala Asn Ser Ser His Leu Thr Val His Met Arg Thr His
                 365                 370                 375

 Thr Gly Glu Lys Pro Tyr Gln Cys Lys Glu Cys Gly Lys Ala Phe
                 380                 385                 390

 Ile Asn Ser Ser Ser Phe Lys Ser His Met Gln Thr His Pro Gly
                 395                 400                 405

 Val Lys Pro Tyr Asp Cys Gln Gln Cys Gly Lys Ala Phe Ile Arg
                 410                 415                 420

 Ser Ser Phe Leu Ile Arg His Leu Arg Ser His Ser Ala Glu Arg
                 425                 430                 435

 Pro Phe Glu Cys Glu Glu Cys Gly Lys Ala Phe Arg Tyr Ser Ser
                 440                 445                 450

 His Leu Ser Gln His Lys Arg Ile His Thr Gly Glu Arg Pro Tyr
                 455                 460                 465

 Lys Cys Gln Lys Cys Gly Gln Ala Phe Ser Ile Ser Ser Gly Leu
                 470                 475                 480

 Thr Val His Met Arg Thr His Thr Gly Glu Arg Pro Phe Glu Cys
                 485                 490                 495

 Gln Glu Cys Gly Lys Ala Phe Thr Arg Ser Thr Tyr Leu Ile Arg
                 500                 505                 510

 His Leu Arg Ser His Ser Val Glu Lys Pro Tyr Lys Glu Cys Gly
                 515                 520                 525

 Gln Thr Phe Ser Asn Ser Ser Cys Leu Thr Glu Cys Val
                 530                 535

<210> 4022
<211> 1235
<212> DNA
<213> Homo sapien

<400> 4022
 ggcacgaggg tcatcgccgc ggggcggagg cgacagtgtc tagcgggagc 50

 tccgcgtgta gctacgccgg ccgcctggct ttgagacaac gtgattctcc 100

 gcagctggtc gcctacccgt gatgttctgc ccacgtcgag acctgagctg 150

 aaatggcaga cgatctcgga gacgagtggt gggagaacca gccgactgga 200

 gcaggcagca gcccagaagc atcagatggt gaaggagaag gagacacaga 250

 agtgatgcag caggagacag ttccagttcc tgtaccttca gagaaaacca 300

 aacagcctaa agaatgtttt ttgatacaac caaaggaaag aaaagagaat 350

 accaccaaga ccaggaaaag aagaaagaag aaaattactg atgttcttgc 400

 aaaatcagaa ccaaaaccag ggttacctga agacctacag aagctgatga 450

 aggactatta tagcagcaga cgcttggtga ttgaattaga agaactgaac 500

 ctgccagact cctgtttcct caaggccaat gatttgactc acagtctttc 550

 ctcataccta aaaggaattt gtcctaagtg ggtaaaactt aggaagaacc 600

 acagtgagaa gaaatcggtc ctgatgctga tcatctgcag ctcggccgtc 650

 cgagccctgg agctcattag gtcgatgaca gcattcagag gagacggcaa 700

 agttataaaa ttatttgcaa agcacataaa ggtccaggcg caggtaaagt 750

 tgctggagaa gcgtgtggtg cacctgggtg taggaactcc ggggagaatt 800

 aaagaacttg ttaaacaagg tggccttaat ttgagcccct taaaatttct 850

 ggtttttgac tggaactgga gagatcagaa gttgaggaga atgatggaca 900

 ttcccgagat aagaaaggag gtattcgaac ttctggaaat gggagtgctc 950

 agtctgtgca agtcagaatc cttgaaactg ggccttttct aagtctgtgt 1000

 cctaatgaag attccagttt tcacagtaga agttgcatct tatttaatga 1050

 ctctgataca ttgcaagcac tcagtaaata tcagcaaata gtttatgtta 1100

 attgtgtcaa cagatggatc actggaatgt ggggattctg aaacagaaat 1150

 gaaactgtcc ttttgacaac tctcttatat aataaagtat caccggcttg 1200

 tgtatgaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1235

<210> 4023
<211> 279
<212> PRT
<213> Homo sapien

<400> 4023
 Met Ala Asp Asp Leu Gly Asp Glu Trp Trp Glu Asn Gln Pro Thr
   1               5                  10                  15

 Gly Ala Gly Ser Ser Pro Glu Ala Ser Asp Gly Glu Gly Glu Gly
                  20                  25                  30

 Asp Thr Glu Val Met Gln Gln Glu Thr Val Pro Val Pro Val Pro
                  35                  40                  45

 Ser Glu Lys Thr Lys Gln Pro Lys Glu Cys Phe Leu Ile Gln Pro
                  50                  55                  60

 Lys Glu Arg Lys Glu Asn Thr Thr Lys Thr Arg Lys Arg Arg Lys
                  65                  70                  75

 Lys Lys Ile Thr Asp Val Leu Ala Lys Ser Glu Pro Lys Pro Gly
                  80                  85                  90

 Leu Pro Glu Asp Leu Gln Lys Leu Met Lys Asp Tyr Tyr Ser Ser
                  95                 100                 105

 Arg Arg Leu Val Ile Glu Leu Glu Glu Leu Asn Leu Pro Asp Ser
                 110                 115                 120

 Cys Phe Leu Lys Ala Asn Asp Leu Thr His Ser Leu Ser Ser Tyr
                 125                 130                 135

 Leu Lys Gly Ile Cys Pro Lys Trp Val Lys Leu Arg Lys Asn His
                 140                 145                 150

 Ser Glu Lys Lys Ser Val Leu Met Leu Ile Ile Cys Ser Ser Ala
                 155                 160                 165

 Val Arg Ala Leu Glu Leu Ile Arg Ser Met Thr Ala Phe Arg Gly
                 170                 175                 180

 Asp Gly Lys Val Ile Lys Leu Phe Ala Lys His Ile Lys Val Gln
                 185                 190                 195

 Ala Gln Val Lys Leu Leu Glu Lys Arg Val Val His Leu Gly Val
                 200                 205                 210

 Gly Thr Pro Gly Arg Ile Lys Glu Leu Val Lys Gln Gly Gly Leu
                 215                 220                 225

 Asn Leu Ser Pro Leu Lys Phe Leu Val Phe Asp Trp Asn Trp Arg
                 230                 235                 240

 Asp Gln Lys Leu Arg Arg Met Met Asp Ile Pro Glu Ile Arg Lys
                 245                 250                 255

 Glu Val Phe Glu Leu Leu Glu Met Gly Val Leu Ser Leu Cys Lys
                 260                 265                 270

 Ser Glu Ser Leu Lys Leu Gly Leu Phe
                 275

<210> 4024
<211> 1193
<212> DNA
<213> Homo sapien

<400> 4024
 gtctacaccc cctcctcaca cgcacttcac ctgggtcggg attctcaggt 50

 catgaacggt cccagccacc tccgggcagg gcgggtgagg acggggacgg 100

 ggcgtgtcca actggctgtg ggctcttgaa acccgagcat ggcacagcac 150

 ggggcgatgg gcgcgtttcg ggccctgtgc ggcctggcgc tgctgtgcgc 200

 gctcagcctg ggtcagcgcc ccaccggggg tcccgggtgc ggccctgggc 250

 gcctcctgct tgggacggga acggacgcgc gctgctgccg ggttcacacg 300

 acgcgctgct gccgcgatta cccgggcgag gagtgctgtt ccgagtggga 350

 ctgcatgtgt gtccagcctg aattccactg cggagaccct tgctgcacga 400

 cctgccggca ccacccttgt cccccaggcc agggggtaca gtcccagggg 450

 aaattcagtt ttggcttcca gtgtatcgac tgtgcctcgg ggaccttctc 500

 cgggggccac gaaggccact gcaaaccttg gacagactgc acccagttcg 550

 ggtttctcac tgtgttccct gggaacaaga cccacaacgc tgtgtgcgtc 600

 ccagggtccc cgccggcaga gccgcttggg tggctgaccg tcgtcctcct 650

 ggccgtggcc gcctgcgtcc tcctcctgac ctcggcccag cttggactgc 700

 acatctggca gctgaggaag acccagctgc tgctggaggt gccgccgtcg 750

 accgaagacg ccagaagctg ccagttcccc gaggaagagc ggggcgagcg 800

 atcggcagag gagaaggggc ggctgggaga cctgtgggtg tgagcctggc 850

 cgtcctccgg ggccaccgac cgcagccagc ccctccccag gagctcccca 900

 ggccgcaggg gctctgcgtt ctgctctggg ccgggccctg ctcccctggc 950

 agcagaagtg ggtgcaggaa ggtggcagtg accagcgccc tggaccatgc 1000

 agttcggcgg ccgcggctgg gccctgcagg agggagagag agacacagtc 1050

 atggccccct tcctcccttg ctggccctga tggggtgggg tcttaggacg 1100

 ggaggctgtg tccgtgggtg tgcagtgccc agcacgggac ccggctgcag 1150

 gggaccttca ataaacactt gtccagtgaa aaaaaaaaaa aaa 1193

<210> 4025
<211> 234
<212> PRT
<213> Homo sapien

<400> 4025
 Met Ala Gln His Gly Ala Met Gly Ala Phe Arg Ala Leu Cys Gly
   1               5                  10                  15

 Leu Ala Leu Leu Cys Ala Leu Ser Leu Gly Gln Arg Pro Thr Gly
                  20                  25                  30

 Gly Pro Gly Cys Gly Pro Gly Arg Leu Leu Leu Gly Thr Gly Thr
                  35                  40                  45

 Asp Ala Arg Cys Cys Arg Val His Thr Thr Arg Cys Cys Arg Asp
                  50                  55                  60

 Tyr Pro Gly Glu Glu Cys Cys Ser Glu Trp Asp Cys Met Cys Val
                  65                  70                  75

 Gln Pro Glu Phe His Cys Gly Asp Pro Cys Cys Thr Thr Cys Arg
                  80                  85                  90

 His His Pro Cys Pro Pro Gly Gln Gly Val Gln Ser Gln Gly Lys
                  95                 100                 105

 Phe Ser Phe Gly Phe Gln Cys Ile Asp Cys Ala Ser Gly Thr Phe
                 110                 115                 120

 Ser Gly Gly His Glu Gly His Cys Lys Pro Trp Thr Asp Cys Thr
                 125                 130                 135

 Gln Phe Gly Phe Leu Thr Val Phe Pro Gly Asn Lys Thr His Asn
                 140                 145                 150

 Ala Val Cys Val Pro Gly Ser Pro Pro Ala Glu Pro Leu Gly Trp
                 155                 160                 165

 Leu Thr Val Val Leu Leu Ala Val Ala Ala Cys Val Leu Leu Leu
                 170                 175                 180

 Thr Ser Ala Gln Leu Gly Leu His Ile Trp Gln Leu Arg Lys Thr
                 185                 190                 195

 Gln Leu Leu Leu Glu Val Pro Pro Ser Thr Glu Asp Ala Arg Ser
                 200                 205                 210

 Cys Gln Phe Pro Glu Glu Glu Arg Gly Glu Arg Ser Ala Glu Glu
                 215                 220                 225

 Lys Gly Arg Leu Gly Asp Leu Trp Val
                 230

<210> 4026
<211> 1035
<212> DNA
<213> Homo sapien

<400> 4026
 atgggacaat agtattgaat agatttcagc tttatgctgg agtaactggc 50

 atgtgagcaa actgtgttgg cgtgggggtg gaggggtgag gtgggcgcta 100

 agcctttttt taagattttt caggtacccc tcactaaagg caccgaaggc 150

 ttaaagtagg acaaccatgg agccttcctg tggcaggaga gacaacaaag 200

 cgctattatc ctaaggtcaa gagaagtgtc agcctcacct gatttttatt 250

 agtaatgagg acttgcctca actccctctt tctggagtga agcatccgaa 300

 ggaatgcttg aagtacccct gggcttctct taacatttaa gcaagctgtt 350

 tttatagcag ctcttaataa taaagcccaa atctcaagcg gtgcttgaag 400

 gggagggaaa gggggaaagc gggcaaccac ttttccctag cttttccaga 450

 agcctgttaa aagcaaggtc tccccacaag caacttctct gccacatcgc 500

 caccccgtgc cttttgatct agcacagacc cttcacccct cacctcgatg 550

 cagccagtag cttggatcct tgtgggcatg atccataatc ggtttcaagg 600

 taacgatggt gtcgaggtct ttggtgggtt gaactatgtt agaaaaggcc 650

 attaatttgc ctgcaaattg ttaacagaag ggtattaaaa ccacagctaa 700

 gtagctctat tataatactt atccagtgac taaaaccaac ttaaaccagt 750

 aagtggagaa ataacatgtt caagaactgt aatgctgggt gggaacatgt 800

 aacttgtaga ctggagaaga taggcatttg agtggctgag agggcttttg 850

 ggtgggaatg caaaaattct ctgctaagac tttttcaggt gaacataaca 900

 gacttggcca agctagcatc ttagcggaag ctgatctcca atgctcttca 950

 gtagggtcat gaaggttttt cttttcctga gaaaacaaca cgtattgttt 1000

 tctcaggttt tgctttttgg cctttttcta gctta 1035

<210> 4027
<211> 25
<212> PRT
<213> Homo sapien

<400> 4027
 Met Lys Val Phe Leu Phe Leu Arg Lys Gln His Val Leu Phe Ser
   1               5                  10                  15

 Gln Val Leu Leu Phe Gly Leu Phe Leu Ala
                  20                  25

<210> 4028
<211> 14709
<212> DNA
<213> Homo sapien

<400> 4028
 agggaattct ctggggcttt ggggaattta gtgcgtgggt gagccaagaa 50

 aatactaatt aataatagta agttgttagt gttggttaag ttgttgcttg 100

 gaagtgagaa gttgcttaga aactttccaa agtgcttaga actttaagtg 150

 caaacagaca aactaacaaa caaaaattgt tttgctttgc tacaaggtgg 200

 ggaagactga agaagtgtta actgaaaaca ggtgacacag agtcaccagt 250

 tttccgagaa ccaaagggag gggtgtgtga tgccatctca caggcagggg 300

 aaatgtcttt accagcttcc tcctggtggc caagacagcc tgtttcagag 350

 ggttgttttg tttggggtgt gggtgttatc aagtgaatta gtcacttgaa 400

 agatgggcgt cagacttgca tacgcagcag atcagcatcc ttcgctgccc 450

 cttagcaact taggtggttg atttgaaact gtgaaggtgt gattttttca 500

 ggagctggaa gtcttagaaa agccttgtaa atgcctatat tgtgggcttt 550

 taacgtattt aagggaccac ttaagacgag attagatggg ctcttctgga 600

 tttgttcctc atttgtcaca ggtgtcttgt gattgaaaat catgagcgaa 650

 gtgaaattgc attgaatttc aagggaattt agtatgtaaa tcgtgcctta 700

 gaaacacatc tgttgtcttt tctgtgtttg gtcgatatta ataatggcaa 750

 aatttttgcc tatctagtat cttcaaattg tagtctttgt aacaaccaaa 800

 taaccttttg tggtcactgt aaaattaata tttggtagac agaatccatg 850

 tacctttgct aaggttagaa tgaataattt attgtatttt taatttgaat 900

 gtttgtgctt tttaaatgag ccaagactag aggggaaact atcacctaaa 950

 atcagtttgg aaaacaagac ctaaaaaggg aaggggatgg ggattgtggg 1000

 gagagagtgg gcgaggtgcc tttactacat gtgtgatctg aaaaccctgc 1050

 ttggttctga gctgcgtcta ttgaattggt aaagtaatac caatggcttt 1100

 ttatcatttc cttcttccct ttaagtttca cttgaaattt taaaaatcat 1150

 ggttattttt atcgttggga tctttctgtc ttctgggttc cattttttaa 1200

 atgtttaaaa atatgttgac atggtagttc agttcttaac caatgacttg 1250

 gggatgatgc aaacaattac tgtcgttggg atttagagtg tattagtcac 1300

 gcatgtatgg ggaagtagtc tcgggtatgc tgttgtgaaa ttgaaactgt 1350

 aaaagtagat ggttgaaagt actggtatgt tgctctgtat ggtaagaact 1400

 aattctgtta cgtcatgtac ataattacta atcacttttc ttccccttta 1450

 cagcacaaat aaagtttgag ttctaaactc attagaattg ttgtattgct 1500

 atgttacatt tctcgacccc tatcacattg ccttcataac gactttggat 1550

 gtatcttcat attgtagatt taggtctaga tttgctagct ccaagtaatt 1600

 aaggccatgt aggagagcat ggtaaccaca gatagaactg gtattatccc 1650

 aagtggtctg cagactgctg agtggggatg ggatctgctc tctgttgaga 1700

 gttggtaatc attggtttga aatgtgatga aaccactcaa gccaatgaag 1750

 gtgggtgtgt aggtggggag tactttgcca taatatttta aaacattacc 1800

 tggttagagt tctaagtggt acttattttt gtttggttag gggaaagcct 1850

 gaataaaaac agaaatggac acataatatg catattccat agtctttggg 1900

 aggctggaat gtgcctggga tttgggtcta agtgtatgcg taattcttac 1950

 ctcactaaag aatttgcctt gtttttttcc ttttggtgag tgactaaaac 2000

 gtctgggctt ccctgtgtgc gtgctacagt aagcaagcag aggctgtgca 2050

 aaggtgtgag caggatcacg tggaatctgg aggatacatc ttggcttgca 2100

 aactgcctct gtctcctggg tgggactgtt ctgtccttgc actgctgttc 2150

 tgtgttacct cttggggtgt aaggttttgc ttacaggaga caaactttgg 2200

 gcgtagaatg gaagccactg ccagcctctg tgctgagaag gaaggtgctt 2250

 gtttcaaagg gagcagcaag ggaggcttgt tctactcacc tgggcctgtt 2300

 tgcctgagaa ggggagataa gggctgaact gggactagcc agggggacca 2350

 acacaaatgg tgggggatca tgacctgaag gattctttcc ttcccatgag 2400

 ctgcagggct ggttgccgtc cttgcaactg tgtcttattt gcctgtgccg 2450

 ttatatcttg gtgacccctc cacgtgtaca ctactgacaa acgggtggag 2500

 tgctggggag aagtcactgt gccgcccacc tagtaaacct tctgtctgtg 2550

 ctcatggcat ctccaagatg gggcactgct gtgtgcagaa tccagggtcc 2600

 tctttctgct tgcaactcct ttccctggat gccccagaaa caatccaggc 2650

 ctcctttcct atcttacccc tttgctttgc tttttacccc agcacctcta 2700

 taaccgcctt ctcttctttt cagaactcct tgtttctcat cctgtttttt 2750

 atgattacaa aactcttgct tccaccctgg aagataactg ctatagatgc 2800

 ctgtatgtaa atggtgctgt ctccagcaac tggcatgctg aagaagaatt 2850

 gattcacggg gtataaatgt tggggattgg aagtggggat gaaatggcac 2900

 ttgttgatac aggagcagag aggtgaggcc gactgctgaa gacagctcgc 2950

 caccctcctt gcctccactc caatccaggg gctggggcca cattctttgc 3000

 cttcatttat cctcagatca ggtgagatcg acaggaggtg ttgatggcag 3050

 tgccagcaat tattgctaat ccgtttgcat ccttatgcat agatctgaat 3100

 tcagactttg tgaatttcca gaggtgtggg taatataata gaattcagtg 3150

 agtgggcatg gctgatcttg tgcaaattaa aagttatggg gcataagaat 3200

 agcaaaagtt gaacttcttt taaaaaggaa agtaccctga gagccagtat 3250

 tggttgaggc tcttcagtat gcccaggttg gcagcactga gaaccgcagg 3300

 aacggcctgt tgttacaaaa aggagattga ctcagctgcc cttggtgcat 3350

 ctgactgact atgactgctg agagattcca aggaccctta atgccagggc 3400

 taacctctcc atgtgcagtg agacctctgg aggaagtgtc atcctctggc 3450

 tttgtgtggt actcattatg gtgcagtgcg ggcatgaaat gaagacaccc 3500

 aaataggctt acagatacga tatgttttaa atgttcgtat ttaacaaaaa 3550

 catactgaca ctgtttggaa atggcaacag gaagatagca aaatgaatac 3600

 taacattacg aaaagatgaa caggtacatg ttccaaggca ggtggctgtg 3650

 aacttcctct gagtgaaggc atcccctcca gcacctttca gcctgctagt 3700

 taggacgacc cgccgccacc ctccaggacc tccagccctg cactgccttt 3750

 cctctctttt aaataattct tcattgagtt ctaatatgta aaaaaaaaaa 3800

 gtttactgta aagtttgcaa ataaggaaat tttttttaaa agtcctcagt 3850

 aatcttacca gtaacaattg ttatgggcac atttgctttt ggaagatttc 3900

 ttttgtatgc atgggataag tacattttta aacaaaaatg ggattatgcc 3950

 ataaattcta ttttgtgact ttaatatata gtgaacacct tttttaatga 4000

 tgacaggatg ttcccttgca tggctgtatc aatttaaaca atcttgtttc 4050

 aatgggcata cagggtattt tctagttttt ttttcctctt agaaaataat 4100

 acttgcgatg actttccttg tagctcagac tttttcacgt ctgttgttat 4150

 ctctttggga atgctgaata catacatttc gagaaggaaa tgactgttaa 4200

 actcttaaga cttcaggttc atattgctaa actgcccagc agggagggat 4250

 tttttcaatt agtgttctca ctggtgaggc aaacctgatg ccttcccctc 4300

 ttcctcagaa ccggctttat cacattgaaa acctttgctc ctccgacgga 4350

 tcgagtctgc tttccctgtg gatgtgagca ttgctttgtc tgctggtgac 4400

 tgaacatctc taccatgtgt caattggcca tttgtggtgt gtgtgtgtgt 4450

 gcgtgtgtgt gtgtgtgtgt gtgtgtatga ttttctaatt cctagtcatt 4500

 tttctattga ttgttttgca aaagccattt acatcttaag gatattgata 4550

 atcttttgtt atatttgatg caaatatttt tttccagttt ataggttgcc 4600

 ttttaatttt gtgtttcagg tagataaaag ttaaacgatt ttcttaggtt 4650

 agtttatcac tgtggtttct gaacttgtta tgtgtagatc ttttccaccc 4700

 caagagtaca taaatattaa tccatacttt cttatggaac ttgtatggtt 4750

 tcgtttttta catttaaacc ttcttccccg tggtgtgtgt tgtggaatct 4800

 gtgtttgtgt gaggaggggc atggtgctct cagaacccac ctcctgtggc 4850

 cagagagccc tgtcctgtga gggtggttat cacagtggca gggttcaatt 4900

 cagaagacct tgagggcagg ctgatgtttc ctgaatgggc ccctggttgt 4950

 tgcttgtccc tgactctcca tttccccatc tgagtggatt tggacctaat 5000

 agggcactgg agctggttcg aatcctgact ggactacttg gcaactttat 5050

 gtctgggagc aagttactta acctccccaa gcctgtgtct gtgaaatgcg 5100

 ggtaaatgaa tgtagatgtt tggcagcagc tactccttgt tgagctctca 5150

 cagtgaactc tcctgcctct gccctccttc cccgcctccc ctggtgccta 5200

 gcgtcaggtc tagccacttc ctcctgggcc cctctccctt ttctgtggct 5250

 ggctgcctgc ccgcctggcg ctggaccttt catgtaacgg gaatcagcat 5300

 gtatattctg gtctggtctg tttctacact taattttgtt tccagtagta 5350

 tttccctgta ccggcagagt tcacaaacac atttgaagag gctttttctc 5400

 aggattctta accttcccaa aggaagtccc atggatgggt ttctagaagt 5450

 ctataaatgc tctgaaattg tatttttctg tggaaagcat aactttcatc 5500

 tgcttgttcg tgctcaaaaa agatcatgaa tgaatgattg catgatttta 5550

 tgccattgtg cttatactaa aggatatgta gcccatctct tgagctgtta 5600

 aactgttttg actactttaa atcgtgcagc tgtgagcatc tctgtaaatt 5650

 tagtgtacac atgtatcccc tggagtggca ttgcctcggc agtgagcact 5700

 tatggtttta taactctctt cacagactca aatgactcca gaaagctaca 5750

 cttcctgttg tgagtatatg atatccattt ccctacatag ccactaacat 5800

 caggttttta caattttatt tatttcttgc tactttaaga aatttttgtg 5850

 gtgaaataca tataatagaa gttgactatc tgaatcattt ttaagtatac 5900

 attcagtagt gttaagtatg tcgccattgt tgtacaacca atctccagaa 5950

 ctttttcatc ttgcaaaaca aactctgtac ccattaaata acattaaaca 6000

 ttccattccc tccagcctca gcaaccccat tctactttct gtttctgtga 6050

 gtttgactat tccaagcact tcatatcagt taaatcatga agtatttgtc 6100

 tgtctgtgac tggcttattt ctctgagcac agtgtcctcg agatgcgtct 6150

 atgttgtagc atatgtcaga atttccttcc tttttaaaag atccaaataa 6200

 tattcttatt ttatatcttt tttttatcca ttcatccatt agtggacact 6250

 tgggttgctt ttggctattg taaataatgg tgctatgtac aaatatctat 6300

 attattgtat ttacaagtat aatgctgtaa tgtacacaca tctttttgag 6350

 atcctacctt cagttctttt gagtatatag ccagaagtgg tattactaaa 6400

 tcttacgata tttctatttt taatttattg aggaaccact gtagtttttc 6450

 atagcaactg caccatttta cgttctcacc aagagtgcac aagggttccg 6500

 aggttcccac atcctcccca acacttgtta ttttctgctt tttttagatt 6550

 gcagccatca tagtgggtgt gaggtgacat ttcattgtgg ttttgatttg 6600

 catttcccta atgaggagtg atgctgagca tcttttcata tgcttactgg 6650

 tcatttgtat gttgtctttg gaaaaatgtc tattcaagtc ctttgactat 6700

 tttaaaaatt gggttattag agttatcgtt gttgttgact tgtaggagtt 6750

 tctttctata ttctggatat taatccccta tcagatatat gatttgcaaa 6800

 tatcttctct tattccataa ggttactttt tcactttgtt gattgtgttc 6850

 tttgatgtat agaagttttt agttttgaaa tagtctaatt tatctgtttt 6900

 tacttttgtg gtctgtgctt ttggtgtcat atccaagaaa tccttgccaa 6950

 atccaacgtt ataaggtact tttaaggtat tttagttgtc ttagtctata 7000

 tttctgtact cacctttctt tatccactca tcagttgatg ggcatgtagg 7050

 ttggttccat atctttgcaa ttctgaattg tgctgtgatc aggtgtcttt 7100

 ttagtataat gatttactct cctttgcgta gatacccagt agtgggattg 7150

 ctggatcgaa tggtttttat aattttctat tttaccacag tttctctctg 7200

 catttttcct ctttgaccac taaccatgtg aaattctcat attgaccttt 7250

 ataatgatca tgaactctta gtatcattgg gaaggccaca tttgccactt 7300

 atgattgtaa accttatcct ccatttttcc tgttattgtt ggtgcaaaaa 7350

 gcacctatta taccaggact ttaaaaatca gtctgataag tctttgataa 7400

 gtctaataat aataactgat aagtccattg aatttgcttc tgattacttt 7450

 ttctttagta gctaaacatg tatgtactcc tatgattaca atgaacactc 7500

 ctctccattt aaattaatta tttacattga tgaaatagca aaatgttaat 7550

 gactaaatac tgtcttggtt ttttcgttcc aggtcagtca atattaactt 7600

 cttataattt tctttttttt ctttatgtgt gtgtgtgtgt gtattttttt 7650

 ttttttaatt tcaatggctt ttggggtaca aatggctttt ggtcatatag 7700

 atgaattcta cagtagtgaa gtctgagatt ttactgcacc ggtcacctga 7750

 gtagtgtaca ttgtacccaa tatgtggttt tttatacctt gcccccctct 7800

 taccctcccc actttgagtc tctagtgtcc attatgtcac tctgtatacc 7850

 tttttgtacc cataagttag ctctcactta taagtgagaa cacacagtat 7900

 ttggttttcc attcctgagt tgcttcactt agaataatat cctccagctc 7950

 catccaaaat tgctgcaaaa aaaaaaaaaa ccacaaacat tattttgttc 8000

 ttttttattg ctaagtcata ttccatggtg tagagatacc acattttatt 8050

 tatccactca ctggttgatg ggttggttcc acatctttgc aattgtgact 8100

 tgtactgcca tcaagtgtct ttctggtata atgacttctt ttcctttggg 8150

 tagataccca ggagtgggat tgctagatca aatggttctt aacattttct 8200

 ctctggatct atttctggaa attttaggct ccagtttttg ttgttgttgt 8250

 taataaaatg caatggaatg taatgatcat cacttttcat tatgctttaa 8300

 aatctggtaa atggaggcta gaacactcct gtaaggcaag aatattctct 8350

 ctgttggaac tcaaatacac agaactgggt aaatctcaat cttaatcttt 8400

 gattcaggac acaacatggc tctcttttac ttgctttctt taattgtttt 8450

 ttaataatgt ggtaagcatt tctgaatctc ctatccaata caaaaactag 8500

 gacaatacag acagtaactc ctatggttac aatgaacact cctctccact 8550

 taaattaatt atttacactg atgaaattga aatagcaaaa ttttaatgac 8600

 taaatactgt ctttgatttt ttgttccagg tctgtcaata ttaacttctt 8650

 ataattttct ttttttttct ttatgtgtgt gtgtgtgtgt atatatatat 8700

 atatttaatt tcaatggctt ttggggtaca aatggctttt ggtcatatat 8750

 atgagttcta cagtagtgaa gtctgagatt ttactacacc ttccacttat 8800

 gtggtcccac accacccgcc tcccctgccg cctcctgcca ccccctaggc 8850

 caaggtaata atcatcctga atcctgggtt tatctctcac ttgctttctt 8900

 ttcatataat tttgcaaaag aatctgatct aaatgtgttt ttcagagtat 8950

 atatttatat tttagctgtt cttagagaaa atttattatt ttgcatgtaa 9000

 tcttatggaa cattctcatt taataccatg gtaagattca gcccttgccc 9050

 aggggatagt tcatttagtt tgtttactgg atagagctca tcatgtgact 9100

 atacctcagt tagtttatca gttctcccat ccatggtgac taggttgcct 9150

 ctcagcctct caacaacact gtttctcagt gtccttgtag aagtgatatg 9200

 tgggtgtttt ctccttacac agagttgaaa ggtgacgaca acaacgttgg 9250

 cactaccaat cccccaccct ccagaggggt aaccagtgtt accagtttgc 9300

 tgtgtttcct gctacacctc gccttattca cttccatttg tatctgaaaa 9350

 acgtgttgca tggtttcttt tctatagaag tggtaaaatg ctattgtgtc 9400

 ctgtacatta ttgattactt tttttcattt aacagtaggg agatgcctgg 9450

 gagtacacag agaactgccc tcattgtttt caacttctgc actgtatgtc 9500

 tgtgagttta gccattctgc tgttaatgga aatttacagt attctaatct 9550

 tttgatatta caaacagttc tgtgcgatca tcgtcataca caaccccttg 9600

 tgcacaatgc atgagtgttt ctcagggtag gtaccaagaa gtgaaattcc 9650

 tgggtcatag ggcgtgagtc cgacattttt ctccattctg ccctgttgcc 9700

 ctccagagtg ggtgtccagc tttgcatacc taagtatgag agtatctgtt 9750

 gttcatatcc tctacgacgc tccatatatg aaacttaagt ttctgctagt 9800

 tgccatcttt gatctatcat gtatgcagtg acctactaag actgtaattg 9850

 gtacagtaga ttcttgtcat ctgtgtgtga atttagcatt catgggctta 9900

 atgctgacaa ggcccccagg gtccaagaca tataatcatg tataattttg 9950

 tcaaggtata attttttaaa ttgcttttgt catgtgtctg ctggtgatgc 10000

 ccaacccagt gctctgcacc caggtcacac tgtggctttg tcctctgctt 10050

 atgcctgcat tgcagcaact gtcctgaaga gaccaaaatt atgcagattt 10100

 aggtaagtcc atggctaatg ttattatatt atgtgctatt gtaatggatg 10150

 gggctgtgga gtgtatgaat ttataaatca ctggtcttgt aattaaaatt 10200

 caaacactat agaaaaaggc catgtagaag ataaaagttc ctctataatc 10250

 ccggacccct aagataacta ctaatgacaa cttcatttat attccttcag 10300

 acattttctg gctgtggatg tactaaaatg tatcctatta ttctctgccc 10350

 taaaatggaa tcatacaagg tgtactgtta tttttatggc tctataacat 10400

 gtcatattgt acgtgttggt atggtcattt taaccatttt tctagtgatg 10450

 gctttgaggt tatttgcagt ttcctagcca tctcaaagtg tgctgcgggg 10500

 atctcttttg catccctctg ggtgcagagc tgaggcaccc agaggcagtg 10550

 tccagaggag gcagcatctg taggtgtctt cacctgctct ggctcttggc 10600

 acatctggtt ggtgacactg ttttgtgaga tgggttgaaa gcacgtgctg 10650

 ccaaaataga ataatgttgg tcctctcctc atgtgccgtg gaactggggt 10700

 aaaactgcgt agtggctgca gctgcctgtc cataccggaa tcgagtataa 10750

 cacggtgcct ggcttagcac aaaacagtag tgggtcctgc aggccccaga 10800

 gtctaattcc tggtattctt tcccctacac agattaaata aaccaaaaac 10850

 aaactattct aggaaagcgt ctgtgacatt tgtaaaaagt ggtatttaat 10900

 gatcttttat tcacttgtct gtttagtttg ttgaaatctt aagtggcatc 10950

 ctggtctggg aaggagtgct gtctgcgcct gccctccgct gggcacagcg 11000

 tggctgcttc aggggctaag cacacacttt ctgtcttcta aagggccgcc 11050

 acatgccagg agctcaggtg tgagcccggc tctggctctt acctcatagg 11100

 gtcactcata ggggcacagg gagcagaaca ttgtacacag cgaggcacca 11150

 cccggcttgg catctgcctc ggtggactta ctacctctag aaggaaatac 11200

 ctgagttcct ctggcctcag ctcctagagt gactggtgtg ctgtccctgt 11250

 tactcttctg tcaaggtgac aactgtgtga cccatcatct gtgtgtcaaa 11300

 gcaaggccct gcctgggcct ctgctcctgt gctgacccca aaggcaaatg 11350

 ctttgctagt ttccttccag ttaatttcac ctatgaatag atgtgtgaaa 11400

 actgttcaaa gccatacctg cacatgtttg aacttcaaac cctgtgggtg 11450

 attcagtggc atctttctct aacccccagc ctcccttccc acagaggcca 11500

 ccgtcatggc cagttgctgc agtttctttc cagagaacct gtgtatgtgt 11550

 aaagctgtac aggcgtgggt acaccacaca gcctgtcttg cactgtggac 11600

 tgttgagtta ctagtacatc taggtaagca ccgcatatct gtattcatgt 11650

 ctgccttggt cttttcaaca tctgtgtggt agccgtgttt gaattaccca 11700

 ttcccttttt ggggaaccat taagttgttt cagcaatttt tactgtagat 11750

 aaggctatac cgcatatctg tgtacatggg tttttatgta catgggcaag 11800

 tatatctgtg agagaaaagt ttcctcagga ggaattctgg gcacagcatg 11850

 tgtaaatttc taaatatgat ggacaccccc agcttccacc tcaaggaggt 11900

 tggtcccatt gacatttccc cacaccttca cccaggctgt gcccttaaac 11950

 ttggttattt gtcaatgtga gaagtggaaa atagtattta attgtagttt 12000

 ggatttgtat ttctattggg ttgtatactt actgattaat aataagagct 12050

 ctttacatat taaggaaatt aacccttttc aaatacattc ctatttctca 12100

 ctaatcttta agttttattg taatattttg ctctttagtt tatatatata 12150

 tgtatatata tatatatgta tatatatata tatacatata tatatatata 12200

 tatatatata tatatatata tatatatata tatatatata tatatatata 12250

 tacatatata tatacatata tatatactaa ttttctttta tggttcctgg 12300

 attttgtgag tagtttgaaa aggctaatcc agctgaagat tttgttgttg 12350

 ttgttaaacc ccatgttttc tcctaactct ttttattttt attttggagg 12400

 actctatcta gacttaattt tagcataaca agtgacaggg ttagttagcc 12450

 tgttgtcctt acaccatttt ctggctaata cagctattaa ctattgatct 12500

 gtctattcac gtgccagttc ctaatggttt tacatagtgt aatctgcact 12550

 tcaaaatagc gaagggaagc cctacctcat tattctactt ttccagaatt 12600

 ctcctggcta ttccaggctg catgtttacc ttaaccttcc ctgtgatgtc 12650

 ttcatgccgt tgtcttctta tgcaagaata aggtacgtct ttccatccac 12700

 tcacgtctat ttaatttgac tttgcattac acagaaagct ggtcttggtc 12750

 tgtctacctc ggcatctagt tgtcctcact gccccctagc cgaccccacc 12800

 ccatctgact gactacccca tcacagagta cttttattta cgttttgctc 12850

 tgcctaatgg ttacttgata ctgtcacgcc gacagtgtcc agttcagtgg 12900

 tctttgcagt tgaaatgctc ccgtacacac tgtcttgtta aaaatgccag 12950

 taagttcata caaacccagc ttgcacccaa ggtcacattc agagagcgta 13000

 gggctgggat gggttgtttt ccaagcttct gccactgtgt ggctagctct 13050

 tcccactggg aagttctgtg tacccggaat gtcggagtgg agtcctgttc 13100

 tagtgtccag cacctgaccc tgtgcccaac ccctcaacag cctattcctg 13150

 ctgtccacag cctgctggaa ctttttacaa aatatgttgc catgctggac 13200

 cctgggcact ggacataagc cccctggcag cctttttcat gtcacccaaa 13250

 ggggtaattg tcctactggt ggtctgtaag atgagttagg gtgacttgct 13300

 aatagacatt gtaaatctta atatttatgt atgtatttta ttattaccgg 13350

 ttttccattt atgatggtaa tattgtttct tctaagaata tttatttttc 13400

 cttctaaata ttgagataaa attcatgctt ttgaaatgtt ctattcagtg 13450

 gcttttagta tatttgctat gttgtgcaac catcgacact atccatttct 13500

 agaacttttt cgtcatccca aacagacgct ctgtattcat aaaaaaataa 13550

 cttcctacct gtctctcccc ctagtctttg gtaacctttg ttatactggt 13600

 aaactttgtt gtgctctctg tctgtgtgaa tttgcctatt ctaggggcct 13650

 catataagtg taatcataca gtatttgtct ttttgggtct gtctgatttc 13700

 acttagcggg ttttcagggt tcattcatgt tgcagcatat aacagtactg 13750

 cgttcctttt tctggctgaa taatattcca ctgtatggat agaccccatt 13800

 ttgtttattc acacatcatt tggacatttg gattatttct ggtttttggc 13850

 tattatgaac aatggtgcta tgaacagttg cgtacaagtt tttgtgtgaa 13900

 catatgtttt caattctctc attatatacc taggagtaga attactgggt 13950

 catatggtaa ctgtatattt ttgaggaact gccaaactat tttcccacgt 14000

 ccatgcacca tttcacattc ccaccagtaa gtaagagggt tccaatttct 14050

 gcgcattctt gccaacacta gttattatct gactttctgg ttataatcat 14100

 tctaatgagt gtgaagtagc ctctggtgtc atttggattt gcatttctct 14150

 gatgagtgat gctatcaagc acctttgctg gtgctgttgg ccatatgtgt 14200

 atgttccctg gagaagtgtc tgtgctgagc cttggcccac tttttaatta 14250

 ggcgtttgtc tttttattac tgagttgtaa gagttcttta tatattctgg 14300

 attctagacc cttatcagat acatggtttg caaatatttt ctcccattct 14350

 gtgggttgtg ttttcacttt atcgataatg tccttagaca tataataaat 14400

 ttgtatttta aaagtgactt gatttggctg tgcaaggtgg ctcacgcttg 14450

 taatcccagc actttgggag actgaggtgg gtggatcata tgaggaggct 14500

 aggagttcga ggtcagcctg gccagcatag cgaaaacttg tctctactaa 14550

 aaatacaaaa attagtcagg catggtggtg cacgtctgta ataccagctt 14600

 ctcaggaggc tgaggcacga ggatcacttg aacccaggag gaggaggttg 14650

 cagtgagctg agatcatgcc agggcaacag aatgagactt tgtttaaaaa 14700

 aaaaaaaaa 14709

<210> 4029
<211> 14
<212> PRT
<213> Homo sapien

<400> 4029
 Met Pro Gly Gln Gln Asn Glu Thr Leu Phe Lys Lys Lys Lys
   1               5                  10

<210> 4030
<211> 1911
<212> DNA
<213> Homo sapien

<400> 4030
 gccagcgcag gggcttctgc tgagggggca ggcggagctt gaggaaaccg 50

 cagataagtt tttttctctt tgaaagatag agattaatac aactacttaa 100

 aaaatatagt caataggtta ctaagatatt gcttagcgtt aagtttttaa 150

 cgtaatttta atagcttaag attttaagag aaaatatgaa gacttagaag 200

 agtagcatga ggaaggaaaa gataaaaggt ttctaaaaca tgacggaggt 250

 tgagatgaag cttcttcatg gagtaaaaaa tgtatttaaa agaaaattga 300

 gagaaaggac tacagagccc cgaattaata ccaatagaag ggcaatgctt 350

 ttagattaaa atgaaggtga cttaaacagc ttaaagttta gtttaaaagt 400

 tgtaggtgat taaaataatt tgaaggcgat cttttaaaaa gagattaaac 450

 cgaaggtgat taaaagacct tgaaatccat gacgcaggga gaattgcgtc 500

 atttaaagcc tagttaacgc atttactaaa cgcagacgaa aatggaaaga 550

 ttaattggga gtggtaggat gaaacaattt ggagaagata gaagtttgaa 600

 gtggaaaact ggaagacaga agtacgggaa ggcgaagaaa agaatagaga 650

 agatagggaa attagaagac tttagtgtca gtcaccaaag aaggcctgga 700

 acttccagag gatgaagaag agaaaaagaa gcaggaagag aaaaaaacaa 750

 agtttgagaa cctctgcaaa atcatgaaag acatattgga gaaaaaaagt 800

 tgaaaaggtg gttgtgtcaa accgattggt gacatctcca tgctgtattg 850

 tcacaagcac atatggctgg acagcaaaca tggagagaat catgaaagct 900

 caagccctaa gagacaactc aacaatgggt tacatggcag caaagaaaca 950

 cctggagata aaccctgacc attccattat tgagacctta aggcaaaagg 1000

 cagaggctga taagaacgac aagtctgtga aggatctggt catcttgctt 1050

 tatgaaactg cgctcctgtc ttctggcttc agtctggaag atccccagac 1100

 acatgctaac aggatctaca ggatgatcaa acttggtctg ggtattgatg 1150

 aagatgaccc tactgctgat gataccagtg ctgctgtaac tgaagaaatg 1200

 ccaccccttg aaggagatga cgacacatca cgcatggaag aagtagacta 1250

 atctctggct gagggatgac ttacctgttc agtactctac aattcctctg 1300

 ataatatatt ttcaaggatg tttttcttta tttttgttaa tattaaaaag 1350

 tctgtatggc atgacaacta ctttaagggg aagataagat ttctgtctac 1400

 taagtgatgc tgtgatacct taggcactaa agcagagcta gtaatgcttt 1450

 ttgagtttca tgttggttta ttttcacaga ttggggtaac gtgcactgta 1500

 agacgtatgt aacatgatgt taactttgtg tggtctaaag tgtttagctg 1550

 tcaagccgga tgcctaagta gaccaaatct tgttattgaa gtgttctgag 1600

 ctgtatcttg atgtttagaa aagtattcgt tacatcttgt aggatctact 1650

 ttttgaactt ttcattccct gtagttgaca attctgcatg tactagtcct 1700

 ctagaaatag gttaaactga agcaacttga tggaaggatc tctccacagg 1750

 gcttgttttc caaagaaaag tattgtttgg aggagcaaag ttaaaagcct 1800

 acctaagcat atcgtaaagc tgttcaaaaa taactcagac ccagtcttgt 1850

 ggatggaaat gtagtgctcg agtcacattc tgcttaaagt tgtaacaaat 1900

 acagatgagt t 1911

<210> 4031
<211> 3562
<212> DNA
<213> Homo sapien

<400> 4031
 cagaaccaga aggtgaagtc gggcccccta agatcaacgg agaggcccag 50

 ccgtggctgt ccacatccac agaggggctc aagatcccca tgactcctac 100

 atcctctttt gtgtctccgc caccacccac tgcctcacct cattccaacc 150

 ggaccacacc gcctgaagcg gcccagaatg gccagtcccc catggcagcc 200

 ctgatcttag tagcagacaa tgcagggggc agtcatgcct caaaagatgc 250

 caaccaggtt cactccacta ccaggaggaa tagcaacagt ccgccctctc 300

 cgtcctctat gaaccaaaga aggctgggcc ccagagaggt ggggggccag 350

 ggagcaggca acacaggagg actggagcca gtgcaccctg ccagcctccc 400

 ggactcctct ctggcaacca gtgccccgct gtgctgcacc ctctgccacg 450

 agcggctgga ggacacccat tttgtgcagt gcccgtccgt cccttcgcac 500

 aagttctgct tcccttgctc cagacaaagc atcaaacagc agggagctag 550

 tggagaggtc tattgtccca gtggggaaaa atgccctctt gtgggctcca 600

 atgtcccctg ggcctttatg caaggggaaa ttgcaaccat ccttgctgga 650

 gatgtgaaag tgaaaaaaga gagagactcg tgacttttcc ggtttcagaa 700

 aaacccaatg attaccctta attaaaactg cttgaattgt atatatatct 750

 ccatatatat atatatccaa gacaagggaa atgtagactt cataaacatg 800

 gctgtataat tttgattttt tttgaataca ttgtgtttct atattttttt 850

 tgacgacaaa aggtatgtac ttataaagac atttttttct tttgttaacg 900

 ttattagcat atctttgtgc tttattatcc tggtgacagt taccgttcta 950

 tgtaggctgt gacttgcgct gcttttttag agcacttggc aaatcagaaa 1000

 tgcttctagc tgtatttgta tgcacttatt ttaaaaagaa aaaagccaaa 1050

 tacattttct gacattgtaa gattgcctta ctgtctgtca ttccttattg 1100

 ctggcccctt tctcaggccg gaggccaagt ggtggagaag gaaaggaaat 1150

 gatcgaacgg gcatgttgtc aagtgggcat gccactggga aataccacca 1200

 gtttaccctg aaacattgtc ctcagaggag taggaaagtg gattttgaat 1250

 ctctattttg ctcaaaagtt cagttcctga gatactgatg actgagagtg 1300

 ctgctgggaa attttcagga ttgtgtggtc ttttggggtt ttttgttttt 1350

 ttttttttaa gacaaagttg accgctgttc actgtccacg tgatcagttg 1400

 taagattaca atgctgcatg ctagttggtt acataagata caattccagt 1450

 gatggaaggc ggttataatg gatggtggtg tgtacaagat ggcactgcca 1500

 tctttgagca gagcccagct ctgcagcgcc acttcatctt tttaaacacc 1550

 ctagaggtct gtttgttgtt gctgttgtcc tttattttga aagagttgca 1600

 agagaagtta cagtccaggt gaacttggag attgtgggat tggttttgtt 1650

 tctgttttgt tttgtttatc atttacctgt agtgctattg ctgttgatac 1700

 tatcacctat accctgtttc tagtgagtgc tgaatacagt atggtacaat 1750

 gacagtaaca gccgcgtggt gctgccagga ctgcccttgg gcatatcagt 1800

 gacagcccaa atgtgggtgg aggaaacctg taatttcctt cttaacatgt 1850

 gtttgaaata ccaagtgaat aatactgttc tggaaaaaaa tgataaacta 1900

 gtggaaatta aagaaattaa gggttttata taatagacag gccccacctc 1950

 tcaaaatatt tttagaagtc tttttgtaaa ctaatttctt ttgatcacta 2000

 ttttgcatca gtaaaatgat ttttttaaaa ccaataaatc atcaattatt 2050

 agaaatagtt gtctcacagt gatactggtt tttcttttgt gctgttatga 2100

 tttaacattg acaggaacac tattttaaat ccttacgttc aggtgtttgt 2150

 aacttggcct tataattagg ctgaattatg gcttcaaggt ctacaattta 2200

 tgtgtatggt tcacagccta gcttctattt acatttgaaa atacagattt 2250

 ttaccaactt tggattcttt tttagttata tgtttgtctt tcctttttaa 2300

 attgttcaaa actatttttt aatggtcaag ttactaacac ttgaaaatca 2350

 gatactgcac caaatacagt gtttttccgt agtgttttta atgagtgcac 2400

 ctattactac tgtgcgagaa ttcatgtttt accagtcatt gttatattac 2450

 aaacagactt gcatgattaa ccagttgtta cacttacttt ttcaagttgg 2500

 agtatatatg actcagtgca gactggtctc tcttatgtga atgcacacat 2550

 gcagaaatgc agagtcaatt ttacatgccc ataaagacat ttgtaaagaa 2600

 ttcagctctt atggtctgtt gtataaatgt gtatctaggc actttggaat 2650

 ttgacctcac agatgttaca acttgatcag tcgtttgacc taatttgtgg 2700

 tagctatctg tatgttttgc aatcttaata cagacatgct ttccaaaaag 2750

 attaatacag aaccatcctg ccgttttgga taagtctatc cagctgtgga 2800

 aagggcaacc tgtggtttct ctgtactggt gtttaatggg ggaagaatat 2850

 gaacagcttt aaagagctgt gtattgtggt tactactatt aaaaaataag 2900

 atctgcacga gtctgactgg cctttgggtg gcctttgtgg acggctcgta 2950

 gctggaaagt gttgatctgg gttttctggc attcttttaa gttaaaaagt 3000

 taacatcggg acatgggttt gatcttttgt tgtacctgat gacagtgcag 3050

 agattctcca cagctggata aaaatgtcac aaagctactt actgtacatg 3100

 ggcagtatca gatttcaaat cctaatattt cagctgtgct tttaatactc 3150

 aaaatattag gggatggggt gttgaagctt tccctttttt gcttttaaca 3200

 atttatagaa tttaacagat gtactgtctt tcatgtggcc tcacatttaa 3250

 agttatgaga acatacacat ggtttacaac ttttactata tacctttcct 3300

 tggccaccaa gtattttaaa agtgtgccac cttttaacct ttactttttt 3350

 taagttgaag gtgatacttt ttctatatat gatgaaactc atgtcaactg 3400

 aagtgagtgt aatctcagat accaacatta ttatatttta aaatcacgct 3450

 atggaaatat cacctgaatt ctgtcatttg tcagatttac agtacctttt 3500

 tttctttaac ttttagcatt aaataaaaat aaaattggga gcactgaaaa 3550

 aaaaaaaaaa aa 3562

<210> 4032
<211> 1850
<212> DNA
<213> Homo sapien

<400> 4032
 cgcgctcgca gctcgcaggc gccgcgtagc cgtcgccacc gccgccagcc 50

 cgtgcgccct cggcgcgtac ccgccgcgct cccatccccg ccgccggcca 100

 ggggcgcgct cggccgcccc ggacagtgtc ccgctgcggc tccgcggcga 150

 tggccaccaa gatcgacaaa gaggcttgcc gggcggcgta caacctggtg 200

 cgcgacgacg gctcggccgt catctgggtg acttttaaat atgacggctc 250

 caccatcgtc cccggcgagc agggagcgga gtaccagcac ttcatccagc 300

 agtgcacaga tgacgtccgg ttgtttgcct tcgtgcgctt caccaccggg 350

 gatgccatga gcaagaggtc caagtttgcc ctcatcacgt ggatcggtga 400

 gaacgtcagc gggctgcagc gcgccaaaac cgggacggac aagaccctgg 450

 tgaaggaggt cgtacagaat ttcgctaagg agtttgtgat cagtgatcgg 500

 aaggagctgg aggaagattt catcaagagc gagctgaaga aggcgggggg 550

 agccaattac gacgcccaga cggagtaacc ccagcccccg ccacaccacc 600

 ccttgccaaa gtcatctgcc tgctccccgg gggagaggac cgccggcctc 650

 agctactagc ccaccagccc accagggaga aaagaagcca tgagaggcag 700

 cgcccgccac cctgtgtcca cagcccccac cttcccgctt cccttagaac 750

 cctgccgtgt cctatctcat gacgctcatg gaacctcttt ctttgatctt 800

 ctttttcttt tctccccctc ttttttgttc taaagaaaag tcattttgat 850

 gcaaggtcct gcctgccatc agatccgagg tgcctcctgc agtgacccct 900

 tttcctggca tttctcttcc acgcgacgag gtctgcctag tgagatctgc 950

 atgacctcac gttgctttcc agagcccggg cctattttgc catctcagtt 1000

 ttcctggacc ctgcttcctg tgtaccactg aggggcagct gggccaggag 1050

 ctgtgcccgg tgcctgcagc cttcataagc acacacgtcc attccctact 1100

 aaggcccaga cctcctggta tctgccccgg gctccctcat cccacctcca 1150

 tccggagttg cctaagatgc atgtccagca taggcaggat tgctcggtgg 1200

 tgagaaggtt aggtccggct cagactgaat aagaagagat aaaatttgcc 1250

 ttaaaactta cctggcagtg gctttgctgc acggtctgaa accacctgtt 1300

 cccaccctct tgaccgaaat ttccttgtga cacagagaag ggcaaaggtc 1350

 tgagcccaga gttgacggag ggagtatttc agggttcact tcaggggctc 1400

 ccaaagcgac aagatcgtta gggagagagg cccagggtgg ggactgggaa 1450

 tttaaggaga gctgggaacg gatcccttag gttcaggaag cttctgtgta 1500

 agctgcgagg atggcttggg ccgaagggtt gctctgcccg ccgcgctagc 1550

 tgtgagctga gcaaagccct gggctcacag caccccaaaa gcctgtggct 1600

 tcagtcctgc gtctgcacca cacattcaaa aggatcgttt tgttttgttt 1650

 ttaaagaaag gtgagattgg cttggttctt catgagcaca tttgatatag 1700

 ctctttttct gtttttcctt gctcatttcg ttttggggaa gaaatctgta 1750

 ctgtattggg attgtaaaga acatctctgc actcagacag tttacagaaa 1800

 taaatgtttt ttttgttttt cagaaaaaaa aaaaaaaaaa aaaaaaaaaa 1850

<210> 4033
<211> 142
<212> PRT
<213> Homo sapien

<400> 4033
 Met Ala Thr Lys Ile Asp Lys Glu Ala Cys Arg Ala Ala Tyr Asn
   1               5                  10                  15

 Leu Val Arg Asp Asp Gly Ser Ala Val Ile Trp Val Thr Phe Lys
                  20                  25                  30

 Tyr Asp Gly Ser Thr Ile Val Pro Gly Glu Gln Gly Ala Glu Tyr
                  35                  40                  45

 Gln His Phe Ile Gln Gln Cys Thr Asp Asp Val Arg Leu Phe Ala
                  50                  55                  60

 Phe Val Arg Phe Thr Thr Gly Asp Ala Met Ser Lys Arg Ser Lys
                  65                  70                  75

 Phe Ala Leu Ile Thr Trp Ile Gly Glu Asn Val Ser Gly Leu Gln
                  80                  85                  90

 Arg Ala Lys Thr Gly Thr Asp Lys Thr Leu Val Lys Glu Val Val
                  95                 100                 105

 Gln Asn Phe Ala Lys Glu Phe Val Ile Ser Asp Arg Lys Glu Leu
                 110                 115                 120

 Glu Glu Asp Phe Ile Lys Ser Glu Leu Lys Lys Ala Gly Gly Ala
                 125                 130                 135

 Asn Tyr Asp Ala Gln Thr Glu
                 140

<210> 4034
<211> 4301
<212> DNA
<213> Homo sapien

<400> 4034
 gctgcgcgca cgcgaccgca tccgggctcc ttcggccccg ccatgggctg 50

 ctgcagctcc gcttcctccg ccgcgcagag ctccaaacga gaatggaagc 100

 cgctggagga ccgtagctgc acagacatac catggctgct gctcttcatc 150

 ctcttctgca ttgggatggg atttatttgt ggcttttcaa tagcaacagg 200

 tgcagcagca agactagtgt caggatacga cagctatgga aatatctgtg 250

 ggcagaaaaa tacaaagttg gaagcaatac caaacagtgg catggaccac 300

 acccagcgga agtatgtatt ctttttggat ccatgcaacc tggacttgat 350

 aaaccggaag attaagtctg tagcactgtg tgtagcagcg tgtccaaggc 400

 aagaactgaa aactctgagt gatgttcaga agtttgcaga gataaatggt 450

 tcagccctat gtagctacaa cctaaagcct tctgaataca ctacatctcc 500

 aaaatcttct gttctctgcc ccaaactacc agttccagcg agtgcaccta 550

 ttccattctt ccatcgctgt gctcctgtga acatttcctg ctatgccaag 600

 tttgcagagg ccctgatcac ctttgtcagt gacaatagtg tcttacacag 650

 gctgattagt ggagtaatga ccagcaaaga aattatattg ggactttgct 700

 tgttatcact agttctatcc atgattttga tggtgataat caggtatata 750

 tcaagagtac ttgtgtggat cttaacgatt ctggtcatac tcggttcact 800

 tggaggcaca ggtgtactat ggtggctgta tgcaaagcaa agaaggtctc 850

 ccaaagaaac tgttactcct gagcagcttc agatagctga agacaatctt 900

 cgggccctcc tcatttatgc catttcagct acagtgttca cagtgatctt 950

 attcctgata atgttggtta tgcgcaaacg tgttgctctt accatcgcct 1000

 tgttccacgt agctggcaag gtcttcattc acttgccact gctagtcttc 1050

 caacccttct ggactttctt tgctcttgtc ttgttttggg tgtactggat 1100

 catgacactt ctttttcttg gcactaccgg cagtcctgtt cagaatgagc 1150

 aaggctttgt ggagttcaaa atttctgggc ctctgcagta catgtggtgg 1200

 taccatgtgg tgggcctgat ttggatcagt gaatttattc tagcatgtca 1250

 gcagatgaca gtggcaggag ctgtggtaac atactatttt actagggata 1300

 aaaggaattt gccatttaca cctattttgg catcagtaaa tcgccttatt 1350

 cgttaccacc taggtacggt ggcaaaagga tctttcatta tcacattagt 1400

 caaaattccg cgaatgatcc ttatgtatat tcacagtcag ctcaaaggaa 1450

 aggaaaatgc ttgtgcacga tgtgtgctga aatcttgcat ttgttgcctt 1500

 tggtgtcttg aaaagtgcct aaattattta aatcagaatg catacacagc 1550

 cacagctatc aacagcacca acttctgcac ctcagcaaag gatgcctttg 1600

 tcattctggt ggagaatgct ttgcgagtgg ctaccatcaa cacagtagga 1650

 gattttatgt tattccttgg caaggtgctg atagtctgca gcacaggttt 1700

 agctgggatt atgctgctca actaccagca ggactacaca gtatgggtgc 1750

 tgcctctgat catcgtctgc ctctttgctt tcctagtcgc tcattgcttc 1800

 ctgtctattt atgaaatggt agtggatgta ttattcttgt gttttgccat 1850

 tgatacaaaa tacaatgatg ggagccctgg cagagaattc tatatggata 1900

 aagtgctgat ggagtttgtg gaaaacagta ggaaagcaat gaaagaagct 1950

 ggtaagggag gcgtcgctga ttccagagag ctaaagccga tggcttcggg 2000

 agcaagttct gcttgaacct agccgacggt tatggaaacc cattgacatt 2050

 ccaaaacaat atatacacac acacataaat cagccaaaat cagagaaaag 2100

 gaacagggat ttaatacctt ttttatgctt atttttgtca aacatgtact 2150

 cctttcatac gggtggcttt tacaaggcaa cttccgtcat ttaatgtttt 2200

 caactgtaat tgtcttaatg gaaatgttaa aattcatatc tgattaacat 2250

 ttttaataac ttagaggaga ttttaacttt atttaaaaat aggtaaaatt 2300

 attgtaccta attatgtcta aagtttattc aggggtaatt tccctgatgt 2350

 ctgtataaaa tcaagatctt attttactga tgcataagtc ctagtgggtc 2400

 aagactaggc atatgctttc agataaataa ggaattactc caatcagttt 2450

 tccccaatca aagaagccat gtcattttac ttttagaaac atacaattgg 2500

 gcccaatatg ggaattttca taatagttca tacatttgtc agccaacatt 2550

 aaaaggtaac caactcctca ggtatttgta gtttacccta acgcttcttt 2600

 aaaagaaagt aggtaaaaaa agaaaagggt agataatctt tcgtatgcaa 2650

 acttttccct tatattttgt ctttctttcc tttttgactt tagtagcatc 2700

 ctccacacat ttgtgtgcct gatttgaaag gaagctgggg cacccagcga 2750

 gtttagcctt taagtttctg tgtattgatt tgcagattaa gtaatgctga 2800

 gaggaataaa gaagggacag aaacatggaa cataaagcat tgaaaattcc 2850

 ggtgcttggg cttcggcttc agagtaacgt cagtggctta gggttaaacg 2900

 gccattttat tcaaatgctt gctatacaat ctgaaaacac actggcaggt 2950

 gctcctctcc ttggcaattc attgagtatc cagagttcta cgatgtttaa 3000

 ctgaagaatt ggctaatgtt ttgatcctcc agtgtgactg ttgtttttgt 3050

 ttgggggtgg gtttggggtt ttttgctttt ttattcctga agcttaccag 3100

 atatgaatgg ctaatactcc attgttctgc ttgttgtaat ggtgaatgct 3150

 ttaagaaaaa aaagtgtaat ttgctaagaa taattcatga tctgtttatg 3200

 cgataactcc tttttgttac aattttttta aaaaaagcta tttttgttaa 3250

 tgtaaagtaa atatttcaga gcaaattttt taaacttatt gcactaaata 3300

 caggctctgt acaaaaaaaa aaaaaaaaaa gcctcagcat tttatcattc 3350

 catggaagga gaatcttttg aaagaaagca ttgcctccta ccagaactag 3400

 acagtgaatt agatcggtat tatggaaatg catacaagta atgtcactag 3450

 ggcttaataa gcagccgttt gctaatgtgc ttcctttcaa agggttggac 3500

 ctttaaattg ctgcaaaagg taaattgtat ttttttttaa gtattggtgt 3550

 tctttactct agctaggcta aaatttgcta aatgccttgg tttcttttaa 3600

 aagttcatgt aatatttctg atttttcaga atatttgcaa taagagtctg 3650

 gattttaaaa aacacatgca tacacacaat taagagctca tgtcttagca 3700

 agatctggga aaccaacatt gcgagagtag ctattttgaa agaataattc 3750

 tccagaagtt aacatctaat atctagtatc accaaacagt atcgctgttc 3800

 tcttttattc atttgaaatg aatataatta tataactaac aattgtccaa 3850

 atagatgaga gagcaaatca tgtgagaaaa ttcagaatac catctgtttc 3900

 atagccgcac agattttgga ctttcacaaa cattgggaac taaatttaga 3950

 attggcaaaa gtctagaaga tgggtatcaa aacagaagac attccaggag 4000

 ctagcaattt taagaggtgt ccctccaaag tgacctgatg gaagtcctga 4050

 acttggaaat taggttctac tcacttggac atccctgcat catggactgt 4100

 tgctgctccc tgttccatat gctcgcaatc tcagctattt ggaagctacc 4150

 aggaatgctt tctaattatc atttgcaact agaactgtaa tcagaaagaa 4200

 attttgtatt tttgtataac ttgattgtgt gccattttat ataacaggtc 4250

 ctgttttaca aataaatttt gttttactaa aaaaaaaaaa aaaaaaaaaa 4300

 a 4301

<210> 4035
<211> 657
<212> PRT
<213> Homo sapien

<400> 4035
 Met Gly Cys Cys Ser Ser Ala Ser Ser Ala Ala Gln Ser Ser Lys
   1               5                  10                  15

 Arg Glu Trp Lys Pro Leu Glu Asp Arg Ser Cys Thr Asp Ile Pro
                  20                  25                  30

 Trp Leu Leu Leu Phe Ile Leu Phe Cys Ile Gly Met Gly Phe Ile
                  35                  40                  45

 Cys Gly Phe Ser Ile Ala Thr Gly Ala Ala Ala Arg Leu Val Ser
                  50                  55                  60

 Gly Tyr Asp Ser Tyr Gly Asn Ile Cys Gly Gln Lys Asn Thr Lys
                  65                  70                  75

 Leu Glu Ala Ile Pro Asn Ser Gly Met Asp His Thr Gln Arg Lys
                  80                  85                  90

 Tyr Val Phe Phe Leu Asp Pro Cys Asn Leu Asp Leu Ile Asn Arg
                  95                 100                 105

 Lys Ile Lys Ser Val Ala Leu Cys Val Ala Ala Cys Pro Arg Gln
                 110                 115                 120

 Glu Leu Lys Thr Leu Ser Asp Val Gln Lys Phe Ala Glu Ile Asn
                 125                 130                 135

 Gly Ser Ala Leu Cys Ser Tyr Asn Leu Lys Pro Ser Glu Tyr Thr
                 140                 145                 150

 Thr Ser Pro Lys Ser Ser Val Leu Cys Pro Lys Leu Pro Val Pro
                 155                 160                 165

 Ala Ser Ala Pro Ile Pro Phe Phe His Arg Cys Ala Pro Val Asn
                 170                 175                 180

 Ile Ser Cys Tyr Ala Lys Phe Ala Glu Ala Leu Ile Thr Phe Val
                 185                 190                 195

 Ser Asp Asn Ser Val Leu His Arg Leu Ile Ser Gly Val Met Thr
                 200                 205                 210

 Ser Lys Glu Ile Ile Leu Gly Leu Cys Leu Leu Ser Leu Val Leu
                 215                 220                 225

 Ser Met Ile Leu Met Val Ile Ile Arg Tyr Ile Ser Arg Val Leu
                 230                 235                 240

 Val Trp Ile Leu Thr Ile Leu Val Ile Leu Gly Ser Leu Gly Gly
                 245                 250                 255

 Thr Gly Val Leu Trp Trp Leu Tyr Ala Lys Gln Arg Arg Ser Pro
                 260                 265                 270

 Lys Glu Thr Val Thr Pro Glu Gln Leu Gln Ile Ala Glu Asp Asn
                 275                 280                 285

 Leu Arg Ala Leu Leu Ile Tyr Ala Ile Ser Ala Thr Val Phe Thr
                 290                 295                 300

 Val Ile Leu Phe Leu Ile Met Leu Val Met Arg Lys Arg Val Ala
                 305                 310                 315

 Leu Thr Ile Ala Leu Phe His Val Ala Gly Lys Val Phe Ile His
                 320                 325                 330

 Leu Pro Leu Leu Val Phe Gln Pro Phe Trp Thr Phe Phe Ala Leu
                 335                 340                 345

 Val Leu Phe Trp Val Tyr Trp Ile Met Thr Leu Leu Phe Leu Gly
                 350                 355                 360

 Thr Thr Gly Ser Pro Val Gln Asn Glu Gln Gly Phe Val Glu Phe
                 365                 370                 375

 Lys Ile Ser Gly Pro Leu Gln Tyr Met Trp Trp Tyr His Val Val
                 380                 385                 390

 Gly Leu Ile Trp Ile Ser Glu Phe Ile Leu Ala Cys Gln Gln Met
                 395                 400                 405

 Thr Val Ala Gly Ala Val Val Thr Tyr Tyr Phe Thr Arg Asp Lys
                 410                 415                 420

 Arg Asn Leu Pro Phe Thr Pro Ile Leu Ala Ser Val Asn Arg Leu
                 425                 430                 435

 Ile Arg Tyr His Leu Gly Thr Val Ala Lys Gly Ser Phe Ile Ile
                 440                 445                 450

 Thr Leu Val Lys Ile Pro Arg Met Ile Leu Met Tyr Ile His Ser
                 455                 460                 465

 Gln Leu Lys Gly Lys Glu Asn Ala Cys Ala Arg Cys Val Leu Lys
                 470                 475                 480

 Ser Cys Ile Cys Cys Leu Trp Cys Leu Glu Lys Cys Leu Asn Tyr
                 485                 490                 495

 Leu Asn Gln Asn Ala Tyr Thr Ala Thr Ala Ile Asn Ser Thr Asn
                 500                 505                 510

 Phe Cys Thr Ser Ala Lys Asp Ala Phe Val Ile Leu Val Glu Asn
                 515                 520                 525

 Ala Leu Arg Val Ala Thr Ile Asn Thr Val Gly Asp Phe Met Leu
                 530                 535                 540

 Phe Leu Gly Lys Val Leu Ile Val Cys Ser Thr Gly Leu Ala Gly
                 545                 550                 555

 Ile Met Leu Leu Asn Tyr Gln Gln Asp Tyr Thr Val Trp Val Leu
                 560                 565                 570

 Pro Leu Ile Ile Val Cys Leu Phe Ala Phe Leu Val Ala His Cys
                 575                 580                 585

 Phe Leu Ser Ile Tyr Glu Met Val Val Asp Val Leu Phe Leu Cys
                 590                 595                 600

 Phe Ala Ile Asp Thr Lys Tyr Asn Asp Gly Ser Pro Gly Arg Glu
                 605                 610                 615

 Phe Tyr Met Asp Lys Val Leu Met Glu Phe Val Glu Asn Ser Arg
                 620                 625                 630

 Lys Ala Met Lys Glu Ala Gly Lys Gly Gly Val Ala Asp Ser Arg
                 635                 640                 645

 Glu Leu Lys Pro Met Ala Ser Gly Ala Ser Ser Ala
                 650                 655

<210> 4036
<211> 963
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 947, 953
<223> Unknown base

<400> 4036
 gggggttttt ttcgaggtcg gccgcgtggc tggaagacat ggccactcca 50

 gtcggtgttg agcacggcga gcagtctcag gcctttagtg atgatgatta 100

 aaggtggtgg ctgtggcctt gaaaacagtc atgtgaaaac tcatcacctt 150

 aaggtgttaa gtgtaaggat cttcatgatg aaatttctgt aaatggtgca 200

 gtcagcctca gtttccaaag ccggaaaagg atcctctagt agccacggtg 250

 tggcagctgc tctgaaccag gacctggacc cggacccaaa gtgccatgtc 300

 tttaatgtta gctcccagcg atgccagatg ggatcagcac agccctgcct 350

 ctgctgctaa ttgttcctct aaagtaatcg ccatgcgttc ttcgggcttc 400

 atctttaaag gaatgaagca actgagatta ttctggaaaa ccttttggca 450

 gttagtgaaa ttagagtaca actaagaaca ttttcagacc tccactgtgg 500

 atgacctggg tataatctca caaatcgatg ggactgcaag gattgtaaac 550

 tgaaatgaac atgattatac tctgttggaa gagcctaaga ggaaactgat 600

 gccatgagtt tcagagagta atgcttaacc ccagttacac aggatgccgt 650

 cttgtgtttc ctcttgttta gttacccact acagtgattt tgtgatctgc 700

 taatgggttg ccacccacaa ccattgcttt agcactttta cttcaaatca 750

 atgaaggatt gataaaagtt ctcctggtgt ctccgcagag tgccttccag 800

 gaacagatct ttgcatagaa tatcagtggt ttcctttttt gtttcaaata 850

 gtggtcagaa aatacccagt gttgactcac caaggcaatc agcttccttt 900

 ttcccttttt ttgttttttt ttaacatttt atatttttgc tttattntat 950

 ttnattttat ttt 963

<210> 4037
<211> 63
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 947, 953
<223> Unknown amino acid

<400> 4037
 Gly Gly Phe Phe Arg Gly Arg Pro Arg Gly Trp Lys Thr Trp Pro
   1               5                  10                  15

 Leu Gln Ser Val Leu Ser Thr Ala Ser Ser Leu Arg Pro Leu Val
                  20                  25                  30

 Met Met Ile Lys Gly Gly Gly Cys Gly Leu Glu Asn Ser His Val
                  35                  40                  45

 Lys Thr His His Leu Lys Val Leu Ser Val Arg Ile Phe Met Met
                  50                  55                  60

 Lys Phe Leu


<210> 4038
<211> 2891
<212> DNA
<213> Homo sapien

<400> 4038
 cgttttttaa ttttaaagtt ggggggggtc tcaatttgtt accctgctgg 50

 tctcgaactc ccggacttaa gcgatcctct ggctccaagc ccactaccag 100

 tctcaggttt ctttactaaa agatcactac ctttttttct cttatctgct 150

 gccatgtgag atgtggcttt caccttccgc catgattgtg aggccttccc 200

 agccacgtag aactgtaagt ccaataaacc tcttttgtaa attaaaaaaa 250

 aaaaatcact atttaagata ctaggatgga ttgtgactgt tgaggagtac 300

 ttacatatcc tacatttgac tacattattt ccaaaccaag tattccatcc 350

 aaaggaacat actgctatca tagagaccaa ggagggactg tttaaggttg 400

 ccaaggtgaa gcgagctgag aggctttgtc ctcgtgccag taactctgaa 450

 atctctctta attcctgctg tccaggcagc agaatgccat ggtttcccca 500

 agtaggtagc tgctttagca gttaaagccc aaatgtctgt tctgttgatc 550

 agaggtctct gaatttctga agtggtgttt cgtttctggt gactgagtta 600

 atcctttaca atccctcttg taaagtgtgc taatagaaag aatccacctt 650

 tcaaagctgc agaaccagac cgtgccctaa attgaccaac gtagctgatg 700

 tgcctcagga agtctcttgc cagctgtccc tgtgaagacc cccctcctcc 750

 cccccagctg ctgccttgca cactgaagca tctcagactg tgcaaagccg 800

 tgtagtcatc aagacagtaa atcccagggc ttggttaagt gctgtgtgat 850

 aacttgtttg gatgagactt aacttaaaac cacttacaat aaacttggga 900

 aactaccgtc agctgagttc aaatttactg acgccatgat atgaggatga 950

 aggtttatta cctggtgaca tcatcctgtt ggtgacatca tcctgttggt 1000

 gacaaggtgg tgatacatct ctaatgggac ttccctcagt ggcaggcagg 1050

 ctgccaagca actaaccccc atcaagtgcc agaccctccc agtgttctga 1100

 gagtcatctc catgctaaac agcctgcgtt ttatatgatt tctctaccca 1150

 gccaaaaaaa aaaatggtcc atcatgtacg cagttatcta gtcttaagtt 1200

 atattctggc ttttttctcc cactttatta tggagcagaa gtaagcctat 1250

 catgttctta gaaaggctct taagaggtgt cctggagtcc ttgaatcact 1300

 ttagcatctg gggtaggatg tgccaccagg aggatttggg ctggagcgtg 1350

 tgtgtttgcc tttgacctgg actgctgtct gatcttgctg aacactccac 1400

 cgacatttcc taaagttgct cagtgccaat ccagcaaagc agtccatttt 1450

 cccttggcca agattgagat gtattgtttt agatacagaa gagttcttgg 1500

 atgagccaag gacaagctgg ggtgtcctat attgaacaga cctcgatgaa 1550

 aatcttgaat tcaccccagt gccctctgtt ggcaagggaa ggtgaagatt 1600

 gaaaagttaa aaaagctttt ggccacttga gaggatcagg gccgcaactc 1650

 ttgaagaagc aaagggctca gtgcattggg gtcagcgctg gtacagctga 1700

 aggatgccgg ccttgtgcag gtccctccac agggcagctt ccagggacag 1750

 atcgtggttt gcataaaata tcaatggctt catttttcgt tcgaaatagt 1800

 ggtcggaaaa tttccagtag ttgcttgtga tgaatccata ggcactgacc 1850

 tggtcacagg tatgcaaagc tgtcagcagc atgagagccc cggtactagg 1900

 catatatagg tctccaaaat gtgtgttaat caactttgat ttcaagaacc 1950

 tttctgtcag gtagctgatg aagtccggat gtagcagctt gaatttactg 2000

 gcagaggctt ctggtccaaa ataggcgtgc ggcctgtccc ctttatctag 2050

 gccctcaggg acaggcacgc ccagaatggc cgatctcagc atcacatagt 2100

 cgcggatgtc tgaggggatg aagatatact gcaggtcctg tccttgtggc 2150

 acggaggtga agcccagatt ccagtaggag acgagggagt tcttcatcgt 2200

 gttcacagtg aaaccataga aggaagtctt ggtgcccaca tcgcgctcga 2250

 agcctttgat cacagctcca ttgagtctga atacatagtc atgggcatcg 2300

 atgttgggac cctggcggga cccattcaga atgcctccgt tgcccaccac 2350

 ggcacaccgg atacactttg gaggggtgtc cctgggcggg gcaaacagct 2400

 tggcactctc tgagccgttc agaaggctca gggtggaggc gatgacttgg 2450

 tgagagagcc cccgccagcc atacggggct ttgtgttggc tcaggcggtc 2500

 ccagagcgct ggggtgaaga ggtcccccca cagcagcact ggaatggaga 2550

 gattgaacag gccacggaag tgggggtgcc gctgaatggc caggtgaagc 2600

 aggtgtcggc aggcctggcc ctttcctgtc caagaattcg atgccttgga 2650

 ttgaaagaat gcttcaaatg atgtggtgtc cctggctccg gccgctggcc 2700

 ccgggtaccg ctgcaccgcc gagaagtaca gggcaaagag gagccccgag 2750

 caggcagccg tgagcaggag cagcagccag aagaacgacc cgcgcgggag 2800

 ccccatacag ccccggcccg cgagcgcccc gtccgactga cgtcccaggc 2850

 agaagggaga gaaccgggtg ggccgggtgg cacttgcgga g 2891

<210> 4039
<211> 52
<212> PRT
<213> Homo sapien

<400> 4039
 Arg Phe Leu Ile Leu Lys Leu Gly Gly Val Ser Ile Cys Tyr Pro
   1               5                  10                  15

 Ala Gly Leu Glu Leu Pro Asp Leu Ser Asp Pro Leu Ala Pro Ser
                  20                  25                  30

 Pro Leu Pro Val Ser Gly Phe Phe Thr Lys Arg Ser Leu Pro Phe
                  35                  40                  45

 Phe Leu Leu Ser Ala Ala Met
                  50

<210> 4040
<211> 1990
<212> DNA
<213> Homo sapien

<400> 4040
 atttttcggt ttctagggtt gttacgaagc tgcaggagcg agatggaggt 50

 ggacgcaccg ggtgttgatg gtcgagatgg tctccgggag cggcgaggct 100

 ttagcgaggg agggaggcag aacttcgatg tgaggcctca gtctggggca 150

 aatgggcttc ccaaacactc ctactggttg gacctctggc ttttcatcct 200

 tttcgatgtg gtggtgtttc tctttgtgta ttttttgcca tgacttgttc 250

 gctgatatct aaattaagaa gttggttctt gagtgaattc tgaaaatggc 300

 tacaaacttc ttgaataaag aagacaggac tctcaataga agaatttcac 350

 atctccaagg gacccttcct ttcattttac actttgttac taatttgcag 400

 aactctatta attgggtagg atttcaccca ttcctagcta agttcttaaa 450

 attaaaccct ttggttcgtg tttaaaaact ttcaaacatc tgatggcttt 500

 acaggggctg aatataaaag catttgtact taaaggtctt gtgtattcat 550

 taagaaatat agtaatgtct tttaatgttt taagagttga tcagggttta 600

 ctatgatgca agtaatagga tgattaataa gggaaggttt ttgtgaattc 650

 aaaagtcaat tattcaaaag cagggaaaga ttttgagaga gggaacaaag 700

 tattcttaga ttgcgtagaa gctgctaggt tccagtttta atttttaggt 750

 ttagttggac tctgttatga aaagataggt tatgggtggg cgacaggttg 800

 atacagtctt agagaaagca ggtaatatca aagtattgga aagctagcat 850

 gcatgccctc ttacctgggt atcttccccc ttttttcctt ttaaactctt 900

 gagcctccta taacgaagga ttatgtgttt caaacctatt ttttttttta 950

 ctgtttcatt aagtgtgctt gtgcccaaaa tatttacttg tataatatct 1000

 gtaacttgct taaatacttc agcaaagtca gcatatttac tcattcaaca 1050

 aatatttgag ccaggcatta ttttagacac agcagtgaac aaaacaaaaa 1100

 ggcattcttg ccttcatgga gcttacattc ttattgttat ttaaatctaa 1150

 atgttataaa acaagaattt atattctagg gttgatcagc tagtatttaa 1200

 tcaaaaaggc cacactccca tagcagctac tctaagctgt agtagctaat 1250

 aaaaaatatt aatgttggcc gggcacagtg gctcacgcct ataatcccag 1300

 cactttggga ggccaagggt ggtagatcac ttgaggtcaa gagttgtgac 1350

 accagcctgg ccaacctggt gaaaccctat ctctattaaa aaatacaaaa 1400

 aaatacaaaa aaattagctg ggcatgttgg catgcacctg tagtcccagc 1450

 tatttgggag gctgaggcac gagaattgct tgaatccggg aggtggaggt 1500

 tgcagtgagc caagatgggg ccactgcact ctaacgtggg caacagagac 1550

 cctgtctcaa aaagaaaata ttcctgttag ccctaaaggc tttacatgag 1600

 gaatggtaga agtggtcttt tgtttaaatt agttgcattc agcatatatg 1650

 aattgtctta aatattttgg ggatactccc ccgcctttta aacagggcat 1700

 aagatctggt aaactctctg tatatcttcc tacctttcaa aatcgttctt 1750

 agggttagtc aagtctggaa tataattgct gactataaag ttagcaatta 1800

 tgcttttaag gtgttgtcac atcaacctaa agagaaccat ctatggaagg 1850

 tatggttgaa acatctgtag gaacacagaa ctgggatttc actgagttta 1900

 ccaaatcaac tgtgtgaact gtttctgcac tgcttgctaa tggtttcatc 1950

 taataaatgt ttacttatat aaaaaaaaaa aaaaaaaaaa 1990

<210> 4041
<211> 1469
<212> DNA
<213> Homo sapien

<400> 4041
 ggggggccgg actccgctca gtttccggtg cggcgaacac caaagtccgg 50

 gaacttaagc attttcggtt tctagggttg ttacgaagct gcaggagcga 100

 gatggaggtg gacgcaccgg gtgttgatgg tcgagatggt ctccgggagc 150

 agcgaggctt tagcgaggga gggaggcaga acttcgatgt gaggcctcag 200

 tctggggcaa atgggcttcc caaacactcc tactggttgg acctctggct 250

 tttcatcctt ttcgatgtgg tggtgtttct ctttgtgtat tttttgccat 300

 gacttgttcg ctgatatcta aattaagaag ttggttcttg agtgaattct 350

 gaaaatggct acaaacttct tgaataaaga agacaggact ctcaatagaa 400

 gaattccaca tctccaaggg acccttcctt tcattttaca ctttgttact 450

 aatttgcaga actctattaa ttgggtagga tttcacccat tcctagctaa 500

 gttcttaaaa ttaaaccctt tggttcgtgt ttaaaaactt tcaaacatct 550

 gatggcttta caggggctga atataaaagc atttgtactt aaaggtcttg 600

 tgtattcatt aagaaatata gtaatgtctt ttaatgtttt aagagttgat 650

 cagggtttac tatgatgcaa gtaataggat gattaataag ggaaggtttt 700

 tatgaattca aaagtcaatt attcaaaagc agggaaagat tttgagagag 750

 ggaacaaagt attcttagat tgcgtagaag ctgctaggtt ccagttttaa 800

 tttttaggtt tagttggact ctgttatgaa aagataggtt atgggtgggc 850

 gacaggttga tacagtctta gaaaaagcag gtaatatcaa agtattggaa 900

 agctagcatg catgccctct tacctgggta tcttccccct tttttccttt 950

 taaactcttg agcctcctat aacgaaggat tatgtgtttc aaacctattt 1000

 ttttttactg tttcattaag tgtgcttgtg cccaaaatat ttacttgtat 1050

 aatatctgta acttgcttaa atacttcagc aaagtcagca tatttactca 1100

 ttcaacaaat atttgagcca ggcattattt tagacacagc agtgaacaaa 1150

 acaaaaaggc attcttgcct tcatggagct tacattctta ttgttattta 1200

 aatctaaatg ttataaaaca agaatttata ttctagggtt gatcagctag 1250

 tatttaatca aaaaggccac actcccatag cagctactct aagctgtagt 1300

 agctaataaa aaatattaat gttggccggg cacagtggct cacgcctata 1350

 atcccagcac tttgggaggc caagggtggt agatcacttg aggtcaagag 1400

 ttgtgacacc agcctggcca acctggtgaa accctatctc tagtaaaaaa 1450

 aaaaaaaaaa aaaaaaaaa 1469

<210> 4042
<211> 66
<212> PRT
<213> Homo sapien

<400> 4042
 Met Glu Val Asp Ala Pro Gly Val Asp Gly Arg Asp Gly Leu Arg
   1               5                  10                  15

 Glu Gln Arg Gly Phe Ser Glu Gly Gly Arg Gln Asn Phe Asp Val
                  20                  25                  30

 Arg Pro Gln Ser Gly Ala Asn Gly Leu Pro Lys His Ser Tyr Trp
                  35                  40                  45

 Leu Asp Leu Trp Leu Phe Ile Leu Phe Asp Val Val Val Phe Leu
                  50                  55                  60

 Phe Val Tyr Phe Leu Pro
                  65

<210> 4043
<211> 806
<212> DNA
<213> Homo sapien

<400> 4043
 gtgtgtggac acgctgttcc tctgcttctg tgaggacctg gaaaggaatg 50

 acggctctca ggagcgaccc tacttcatgt cgcccgagct gagagacatc 100

 ctgttgaagg ggagtgcgga ggaggggaag cgggcagaag ccgaggagta 150

 gagatggagg acctggagag gaatgacggc tcggccgaga ggccttactt 200

 catgtcttcc accctcaaga aactcttgaa caagaccaac aagaaggcag 250

 cggagtcctg aaggccccgt gctccccacc tctcaaggag tctcatgccg 300

 cagggtgctc agtagctggg tctgttcccc cagccccttg ggctcacctg 350

 aagtcctatc actgccgctc tgcccctccc catgagccag atcccaccag 400

 tttctggacg tggagagtct ggggcatctc cttcttatgc caaggggcgc 450

 ttggagtttt catggctgcc cctccagact gcgagaaaca agtaaaaacc 500

 cattggggcc tcttgatgtc tgggatggca cgtggcccga cctccacaag 550

 ctccctcatg cttcctgtcc cccgcttaca cgacaacggg ccagaccaca 600

 ggaaggacgg tgtttgtgtc tgagggagct gctggccaca gtgaacaccc 650

 acgtttattc ctgcctgctc cggccaggac tgaacccctt ctccacacct 700

 gaacagttgg ctcaagggcc accagaagca tttctttatt attattattt 750

 tttaacctgg acatgcatta aagggtctat tagctttcaa aaaaaaaaaa 800

 aaaaaa 806

<210> 4044
<211> 122
<212> PRT
<213> Homo sapien

<400> 4044
 Met Pro Arg Gly Ala Trp Ser Phe His Gly Cys Pro Ser Arg Leu
   1               5                  10                  15

 Arg Glu Thr Ser Lys Asn Pro Leu Gly Pro Leu Asp Val Trp Asp
                  20                  25                  30

 Gly Thr Trp Pro Asp Leu His Lys Leu Pro His Ala Ser Cys Pro
                  35                  40                  45

 Pro Leu Thr Arg Gln Arg Ala Arg Pro Gln Glu Gly Arg Cys Leu
                  50                  55                  60

 Cys Leu Arg Glu Leu Leu Ala Thr Val Asn Thr His Val Tyr Ser
                  65                  70                  75

 Cys Leu Leu Arg Pro Gly Leu Asn Pro Phe Ser Thr Pro Glu Gln
                  80                  85                  90

 Leu Ala Gln Gly Pro Pro Glu Ala Phe Leu Tyr Tyr Tyr Tyr Phe
                  95                 100                 105

 Leu Thr Trp Thr Cys Ile Lys Gly Ser Ile Ser Phe Gln Lys Lys
                 110                 115                 120

 Lys Lys


<210> 4045
<211> 2203
<212> DNA
<213> Homo sapien

<400> 4045
 ctgccttacc cctgttttag cctgggaacc agtaattgtg aactcaccag 50

 gttaacatga agagggcatg agagcttatt ccataaggaa ttgtctgaga 100

 catttggtta ccttttctta gtttgtccat tagcaaccgt aactaaaata 150

 gttttggctg tttgggataa ttagctaatt gaatgatttt ttgattcagg 200

 agcagcttgt tgctatatac cattgaaaag ccttcagagc tgagaggtta 250

 gttgatattt tttgttcctt acagcttatg ccaccaagta ggcagtttct 300

 atgatgaatc aaactagctc actatgaccg acagtgaaaa tacatgaaca 350

 cctgagaaac tggagaacgc agggagtggg gggtaaccat gtctgaggaa 400

 tctttcaccc acagctttgt ttttctctag gtactactaa ccaataacct 450

 gcttggctca aaggtgagta atttcacggt attcaatgca ctcagtatat 500

 agggtaggaa aaagtgcctt tttaggcctg tgtttgtgat gacttacatg 550

 gaatctcgtt cggctgatga cttgctgttg agactctgaa atctgatttt 600

 ctgagaatga tgggtgggaa caacataatg cgggatatga gaagcactac 650

 tgacttggtc ttcctccttt cagggccagc accttctctc taaagcccaa 700

 gaggagtttg aggtaaatgg ctttgcaata gttaccatca atggctgcta 750

 tataaaattt tctgtgattt ttgtgtgtga tagcactgtg gtctgggtga 800

 atgtacacag acataactgg cttaacccaa agtctttgat ctcctgaacc 850

 accagtgatg aattgctgct caccagtgat gagttgaata ccgccccagt 900

 ctgatcaatg tgtgactgaa aggtattttc tgagctgtga gcctgccttc 950

 cagtgacatg ttctaaaaat tgcaagttat ttgaggaggc tttacagcca 1000

 ataggaagtt cttgggctaa gtagtgtttc ctataaaatg tgccctgaaa 1050

 cttctttctg ccaagcaata gatacaattg agagattgta aaatgtgaca 1100

 tagaatgaaa gtctctcaag actacatttt tctttcttga ttttgcagga 1150

 aaactaggtg tctgtgttca ctccaggctg aagttacagg tgagtaaacc 1200

 taaatgtaag gtggactatg ctaaaaattc ccaatgaaga aactttcaca 1250

 tgtcttactc tctgtcctag tcccagagcc tgtaaaggtg aacccactgg 1300

 gactggctgg gggagaagag gaagatttgt tccagaagga actgtctgag 1350

 ggatgataaa gatttctata cagagaaagg gagtaatcat cacttgttga 1400

 aaacattggt tttatttttt ccaggtctga gcaaataagg tgtataaaaa 1450

 atggaatctg tcttggagga catcagaagg tgaattttcc aagttcttgg 1500

 acaacctagc tgttgaaaag ctttctgggt ttggggggta tttcagatgt 1550

 accttaaagt gttagcagac acagattaag acactgggag ccaatgaaac 1600

 agcagttgag ggtttgctgt gtatcacatt tctgtatttt atcaccccct 1650

 tcctgcaaca ttatttatct ggaatctacc tgcccttttg ttttttagat 1700

 atcaagggct tggttttgtt acccaggctg gtttcaaggc catagcttta 1750

 agtagatcct ctcaccacag atttgccaaa gtgctgggat tgcaggtgtg 1800

 attcatggca cccagacttt gctgcctttc ttacatgatc caggcccaga 1850

 acccaaactc aggcactgta tagatgacca ctttcgtaaa ctactgacct 1900

 agcttgttgc caattgttga ttgaacttcc cataactcca cttcgtgtct 1950

 gttcctctgt atacagccac cttctgttcc tgtcatgagc ctttaggtct 2000

 ccatttgcat attgcaaata ctatgttcca tgtaggtagc tcattcaggg 2050

 ccttgctctt cacttcaaaa aaggttccct tgaggactgg ctgtcaattt 2100

 gtgttgctgt gttggttgtt gatgaaaata ataaaatgat tgattacgtc 2150

 caaaaaaatc tatgtcggtg cggagaaaga ggtaatgaaa tggcaggaat 2200

 tcg 2203

<210> 4046
<211> 19
<212> PRT
<213> Homo sapien

<400> 4046
 Leu Pro Tyr Pro Cys Phe Ser Leu Gly Thr Ser Asn Cys Glu Leu
   1               5                  10                  15

 Thr Arg Leu Thr


<210> 4047
<211> 753
<212> DNA
<213> Homo sapien

<400> 4047
 attttccggg aagatggcgg cgcacaagtc aggtccggca catgtttccg 50

 cggagcggac ccagcaatga cggatgatat cacctcttct tctctggtga 100

 gagtctgagg atagagactt ttttctcacc atgaatgtca ccccagaggt 150

 caagagtcgt gggatgaagt ttgctgagga gcagctgcta aagcatggat 200

 ggactcaagg caaaggcctc ggccggaagg agaatggtat cactcaggct 250

 ctcagggtga cactgaagca agacactcat ggggtaggac atgaccctgc 300

 caaggagttc acaaaccact ggtggaatga gctcttcaac aagactgcgg 350

 ccaacttggt agtggaaact gggcaggatg gagtacagat aaggagcctt 400

 tctaaggaga ccacccgtta taatcatccc aagcccaact tgctgtatca 450

 gaagtttgtg aagatggcca cattgacttc aggtggagag aagccaaaca 500

 aagacttgga gagctgcagt gatgacgaca accaggggtc caagtcccca 550

 aagattctga ctgatgagat gctgctccaa gcctgtgagg ggcgaacagc 600

 acacaaggct gcccgtcttg ggatcacaat gaaggccaag cttgctcgcc 650

 tagaggccca ggagcaggcc ttcctggctc gtctcaaagg ccaggaccct 700

 ggggcccctc aactgcagtc agagagcaag ccccccaaaa aaaaaaaaaa 750

 aaa 753

<210> 4048
<211> 207
<212> PRT
<213> Homo sapien

<400> 4048
 Met Asn Val Thr Pro Glu Val Lys Ser Arg Gly Met Lys Phe Ala
   1               5                  10                  15

 Glu Glu Gln Leu Leu Lys His Gly Trp Thr Gln Gly Lys Gly Leu
                  20                  25                  30

 Gly Arg Lys Glu Asn Gly Ile Thr Gln Ala Leu Arg Val Thr Leu
                  35                  40                  45

 Lys Gln Asp Thr His Gly Val Gly His Asp Pro Ala Lys Glu Phe
                  50                  55                  60

 Thr Asn His Trp Trp Asn Glu Leu Phe Asn Lys Thr Ala Ala Asn
                  65                  70                  75

 Leu Val Val Glu Thr Gly Gln Asp Gly Val Gln Ile Arg Ser Leu
                  80                  85                  90

 Ser Lys Glu Thr Thr Arg Tyr Asn His Pro Lys Pro Asn Leu Leu
                  95                 100                 105

 Tyr Gln Lys Phe Val Lys Met Ala Thr Leu Thr Ser Gly Gly Glu
                 110                 115                 120

 Lys Pro Asn Lys Asp Leu Glu Ser Cys Ser Asp Asp Asp Asn Gln
                 125                 130                 135

 Gly Ser Lys Ser Pro Lys Ile Leu Thr Asp Glu Met Leu Leu Gln
                 140                 145                 150

 Ala Cys Glu Gly Arg Thr Ala His Lys Ala Ala Arg Leu Gly Ile
                 155                 160                 165

 Thr Met Lys Ala Lys Leu Ala Arg Leu Glu Ala Gln Glu Gln Ala
                 170                 175                 180

 Phe Leu Ala Arg Leu Lys Gly Gln Asp Pro Gly Ala Pro Gln Leu
                 185                 190                 195

 Gln Ser Glu Ser Lys Pro Pro Lys Lys Lys Lys Lys
                 200                 205

<210> 4049
<211> 3703
<212> DNA
<213> Homo sapien

<400> 4049
 gctgctcaag gattgcagtg tatgaggcaa gtggaacagc ctcggaacct 50

 ccgaaaatgg gcacgctcca ggtcccagtt tctatggtca accataccgg 100

 caaatggggc tccgcaatgg tttctcctgg aaaaaccgtg attttggttc 150

 ccgcggacgt ctctatggtt tcgcacagcc tagaaggaac aagaacggca 200

 tttccgggaa gatggcggcg cacaagtcag gtccggcaca tgtttccgcg 250

 gagcggaccc agcaatgacg gatgatatca cctcttcttc tctggtgaga 300

 gtctgaggat agagactttt ttctcaccat gaatgtcacc ccagaggtca 350

 agagtcgtgg gatgaagttt gctgaggagc agctgctaaa gcatggatgg 400

 actcaaggca aaggcctcgg ccggaaggag aatggtatca ctcaggctct 450

 cagggtgaca ctgaagcaag acactcatgg ggtaggacat gaccctgcca 500

 aggagttcac aaaccactgg tggaatgagc tcttcaacaa gactgcggcc 550

 aacttggtag tggaaactgg gcaggatgga gtacagataa ggagcctttc 600

 taaggagacc acccgttata atcatcccaa gcccaacttg ctgtatcaga 650

 agtttgtgaa gatggctaca ttgacttcag gtggagagaa gccaaacaaa 700

 gacttggaga gctgcagtga tgacgacaac caggggtcca agtccccaaa 750

 gattctgact gatgagatgc tgctccaagc ctgtgagggg cgaacagcac 800

 acaaggctgc ccgtcttggg atcacaatga aggccaagct tgctcgccta 850

 gaggcccagg agcaggcctt cctggctcgt ctcaaaggcc aggaccctgg 900

 ggcccctcaa ctgcagtcag agagcaagcc ccccaaaaaa aagaacaaag 950

 aaaaggaggc agaaagagga ggaagaagct acagcatctg aaaggaatga 1000

 tgcagatgag aagcacccag aacatgctga gcagaacatc agaaaaagca 1050

 agaagaagaa aaggcgacat caagaaggaa aggtctcaga tgaaagagag 1100

 ggtacaacta aagggaatga gaaggaggac gctgcaggaa caagtgggct 1150

 tggggaattg aatagcagag agcaaaccaa tcagtccctc aggaaaggga 1200

 agaaaaagaa gaggtggcac catgaagagg agaagatggg ggtcttggag 1250

 gaaggaggaa aaggcaagga ggctgcaggc agtgtcagga cagaggaggt 1300

 agagagcagg gcatatgctg acccatgcag ccgaagaaag aagaggcagc 1350

 aacaggagga ggaggacttg aacctagaag atagaggtga ggaaactgtt 1400

 ttaggtggtg gaaccaggga agcagagagc agagcatgca gtgatggaag 1450

 aagcaggaaa agcaagaaga aaagacagca gcatcaagag gaggaggaca 1500

 tcttggatgt aagggatgag aaggatagcg gggctaggga agcagagagc 1550

 agagcacaca ctggctcaag cagcagaggt aagaggaaga ggcagcagca 1600

 tcccaagaag gaaagagctg gagtcagcac tgtccagaaa gccaaaaaga 1650

 aacagaagaa gagagactaa aggtctggta aaggtagggc tcaattgatt 1700

 gattttcagg agttgaagcc tcaaagacca gggttgatgc aggtctgcag 1750

 gtcttctgca cccccctcaa tgaggagtcc ctcccagaaa ggaaactgat 1800

 ctctgggatg tcagctgctg agaggagcaa gcggtagtac caccccttag 1850

 ttgagggagt cagcacagtc ctttctgcag cttctaaccc aggaccatga 1900

 actcaggtgc ctagagaagc caggcagcta aaggacaagg aatgctgggg 1950

 gctgtgggaa caggaatgca gatacccttt gaaggagcat tcctgctaaa 2000

 agaagctgaa aatgtagacc tatgtgaagt gctctgattt ctaaatattg 2050

 tgaaggttaa gaaaaacata aatttaggtc tatgggctag atttagccca 2100

 cagttgccag tttctagcgc taccaaatga atgaataaac atgagcttgc 2150

 gctcctagcc tagagataaa tcctgactgg catctctgtt cccagcctgg 2200

 gaaggtcctg aatacaaatt agaagatatt ccttggaggc ctttgaagaa 2250

 attccttcgg ttaacctctt tgtagtcttg ctacactgat aagtagaagt 2300

 agctccctgt ctgtgtccca aatgaataag aattgtgtaa aggacagcac 2350

 aactcacttg gcatctaaca gtccattttc attgtttcca aataccatag 2400

 caacctcttg ccctttgtgt tacccctaga gagatggcac ccaatcccca 2450

 gggttgctct ctgacttcca ccattcactg acttttattg ccagaggagc 2500

 tcccaggaat ccacagttct ggaagagagg ggctctaagt ctttattggg 2550

 gagaataccc acccaccttc cctcactgca gacgatagac acactcagtg 2600

 tcagggtagg gtggcaggtt cagctggtac ttcttttcca gagcaggtgg 2650

 cacaaaacga ccccccaggt aatggtagcg accggtaaac tgggttgcag 2700

 attttttggg ggctgtgagg gagatgagca agtctggctg gatccctcca 2750

 gcatttccct tctccacgtc ccatccttct ggatcccagc acctgaggga 2800

 atgtcgatgc tggcaatggg cacagtgagt cccttcagga cactcaggat 2850

 gctgtggaac ggttcccgaa catcgccctt gaagctgaag ccaaagatgg 2900

 catccaccac cagctcatac agttcatcaa tcgtcatggg ctctgcgggc 2950

 atttccccaa ggaaagggat gtccattttc tgacactggg tcaccaatgc 3000

 agtgaagagg ggcttgttag gccttttggg gtaatagatg gttggctcgt 3050

 agccaaagag tttgaggtgt cgagcacaga ccagaccatc tcctccatta 3100

 ttccccgggc cacagatgac caggacagta ggggggctcc tggacatgga 3150

 cgtgggggga tatgccttgg cgatggctgt agcacagctc agcccggcca 3200

 gttccataag ttggtccacg ctgaactggt attcgttaaa tagctcctgg 3250

 tccacggcct gggcctcctc ctggctcagg tacttcacca ccgtgctcgc 3300

 catgacctct gagtcccagc ggccacccga gttcagccgc tgcggtcccc 3350

 accaggtggg tcccgagcga caggcgatgg tctggctttt gatccgcggc 3400

 aggcgcgagc ccgcaaccag cagcccgagg cccagcagcg cccgcagcct 3450

 ggacatccag ctcgcagagc gcgcgccctt cattctgtct tgtatcggtc 3500

 aatcgaccga ttttctccct gcctagttcc agaagggatt tagtggccac 3550

 ttaacaaata tgcaagcaac gttgcaagga atatctgtta aaaataagaa 3600

 aaagtgagtg gcaggaaaat aaaagagcca ggagtggcac atgttatgaa 3650

 gatgtacctt gtgagacgtg gacgtaagtt ggactccagg ctttgctgca 3700

 gcc 3703

<210> 4050
<211> 90
<212> PRT
<213> Homo sapien

<400> 4050
 Cys Ser Arg Ile Ala Val Tyr Glu Ala Ser Gly Thr Ala Ser Glu
   1               5                  10                  15

 Pro Pro Lys Met Gly Thr Leu Gln Val Pro Val Ser Met Val Asn
                  20                  25                  30

 His Thr Gly Lys Trp Gly Ser Ala Met Val Ser Pro Gly Lys Thr
                  35                  40                  45

 Val Ile Leu Val Pro Ala Asp Val Ser Met Val Ser His Ser Leu
                  50                  55                  60

 Glu Gly Thr Arg Thr Ala Phe Pro Gly Arg Trp Arg Arg Thr Ser
                  65                  70                  75

 Gln Val Arg His Met Phe Pro Arg Ser Gly Pro Ser Asn Asp Gly
                  80                  85                  90

<210> 4051
<211> 1847
<212> DNA
<213> Homo sapien

<400> 4051
 agaaacgcgc gcagcggggg cgggaggtcg gtaagctccc cgcccctgcc 50

 cgagaccccg ccccggcccg gccccgcctt tttctctgcc tcccctccct 100

 gcacgtacgg gccccgcccc tcgcgcgacg ttttttgttg acccggaaac 150

 ggattctccg gagccgaggt ccgctcggat ttgtcttctt agtgcttgga 200

 tggtgtgagt gaaaacccag aggaatacat ttggtggctg agctagtaca 250

 atgccatcac cggattccat gaccttcgag gatatcattg tagacttcac 300

 tcaagaagag tgggccctgc tggacacatc ccagagaaag ctgtttcaag 350

 atgtgatgtt ggagaacatc agtcatctgg tctctattgg caaacagctc 400

 tgcaaatcag ttgtgctttc ccaattggag caagtagaga aactttcaac 450

 acaaagaata agcttactgc aaagtgagct ctaagaagca gtgcttcaat 500

 aggaggagga gaaacatggc cagtgagtag agaagttggc attaaacatc 550

 aagagatacc attcattcaa catatctatc agaagggcac gtccaccatc 600

 agcacaatga gatctcatac tcaagaggat ccttttctat gcaatgactt 650

 aggagaagat ttcactcaac atatagcatt gactcaaaat gtgattacct 700

 acatgagaac gaaacacttt gtaagcaaaa agtttgggaa aatcttcagt 750

 gactggttat cctttaatca acacaaggaa attcacacca aatgtaaatc 800

 atatggaagt catctatttg attatgcctt tatccaaaac tctgccctta 850

 gaccacacag tgtgactcac actagagaga taacattgga atgtcgtgtg 900

 tgtgggaaaa cctttagcaa aaattctaat cttaggcgac atgagatgat 950

 tcacactgga gagaaaccac acggatgtca tctatgtggg aaagccttta 1000

 ctcatttaat tattgtgaat acctagaatc tttcttggtc ctgatttctc 1050

 ttgcttaatc cagtctttat ctctaactgc cccttatttg atcaccatgt 1100

 actaggagct ctgatagcca gctcagctcc taatccttga ggcaacattc 1150

 tttttctatt tgaacttcag ttctgtcctt gaatcccgac tagatatttc 1200

 ttgccctctg gtctcagaat tctcttggct tttattcctt gatccacttg 1250

 ccagttttat cactttaccc ttgttcctca tggcttccca tcaagccatg 1300

 ggtattaggt gacagtgtaa tttattagat tctggttttg cccaaatact 1350

 gggcatgctt taataataac tgaaccattt cattatttgg ataggcatgg 1400

 gtaccttatc aagcagatta aaaggatatg gtacccgtcc tttagaaaag 1450

 aacagctaaa accttgttgt ggattatgga tttagcctaa agaaaaataa 1500

 tctggcataa attaagagta agagagaaga ttaatagaaa tttcacttca 1550

 cataacttaa aacatggcta tttcaataaa ggactaaagt ttctcctgga 1600

 tcccagaatt caacctgtat ttataaatgt ataatgtatt tagctacttt 1650

 ttggtttaaa tgaacttgtt gggttagctt ggtaaatgtt ataattttta 1700

 ctattttcta caaagaaaat attttctaat ttaagttgga gctatctgtg 1750

 cagcagtttc tctacagttg tgcataaatg tttttactat aaaatgagct 1800

 aatgtataaa atactgctgt ataccataat aaagatagta atacttg 1847

<210> 4052
<211> 139
<212> PRT
<213> Homo sapien

<400> 4052
 Met Arg Ser His Thr Gln Glu Asp Pro Phe Leu Cys Asn Asp Leu
   1               5                  10                  15

 Gly Glu Asp Phe Thr Gln His Ile Ala Leu Thr Gln Asn Val Ile
                  20                  25                  30

 Thr Tyr Met Arg Thr Lys His Phe Val Ser Lys Lys Phe Gly Lys
                  35                  40                  45

 Ile Phe Ser Asp Trp Leu Ser Phe Asn Gln His Lys Glu Ile His
                  50                  55                  60

 Thr Lys Cys Lys Ser Tyr Gly Ser His Leu Phe Asp Tyr Ala Phe
                  65                  70                  75

 Ile Gln Asn Ser Ala Leu Arg Pro His Ser Val Thr His Thr Arg
                  80                  85                  90

 Glu Ile Thr Leu Glu Cys Arg Val Cys Gly Lys Thr Phe Ser Lys
                  95                 100                 105

 Asn Ser Asn Leu Arg Arg His Glu Met Ile His Thr Gly Glu Lys
                 110                 115                 120

 Pro His Gly Cys His Leu Cys Gly Lys Ala Phe Thr His Leu Ile
                 125                 130                 135

 Ile Val Asn Thr


<210> 4053
<211> 4816
<212> DNA
<213> Homo sapien

<400> 4053
 gcgggcggcc gagcggagcc gagcgcagcc gagccgggcc gagccgggcc 50

 gggccgggcc caggagcgcg cggatgatgc gggcggccag gcgggggtcg 100

 acgggtccct gaagcccgcg ccccgggcca gcaagggagc cccgcgcagg 150

 ccgcgcgcat ccggaggcgg ccgggccccg ccatggccgg ggtcagctac 200

 gcggcgccct ggtgggtgag cctcctgcac cggctgcccc acttcgacct 250

 gagctgggag gccactagca gccagttccg gcccgaggac accgactacc 300

 agcaggccct gctgctcctg ggggccgccg ccctggcctg cctcgccctg 350

 gacctcctct tcctgctctt ctactccttc tggctgtgct gccggcggcg 400

 caagagcgag gagcacctgg acgccgactg ctgctgcacg gcctggtgtg 450

 tcatcatcgc cacgctggtg tgcagcgccg gcatcgcagt gggattctac 500

 ggcaacgggg agaccagtga tggcatccat agggccacct actcgctccg 550

 ccacgccaac cgcacggtgg ccggggtcca ggaccgcgtg tgggacacgg 600

 cggtggggct gaaccacacg gcggagccca gcctgcagac cctggagcgg 650

 cagctggccg ggcggcccga gcccctgcga gccgtacaga ggctgcaggg 700

 cctgctggag acgctgctgg gctacacggc cgccatcccc ttttggagga 750

 acacggcggt gtcgctggag gtgctggcgg agcaggtgga tctctacgac 800

 tggtacaggt ggctgggcta cctgggcctg ctgctgctgg acgtcatcat 850

 ctgcctcctg gtgctggttg gcctcatccg cagctccaag ggcatcctgg 900

 tgggggtctg cctgctggga gtcctggccc tggtcatcag ctggggcgcg 950

 ctgggcttgg agctggctgt gtccgtgggc tccagcgact tctgtgtgga 1000

 ccctgacgcc tacgtgacca aaatggtgga ggagtactcg gtgctgagtg 1050

 gggacatcct gcagtactac ctggcctgct cgccccgcgc cgccaacccc 1100

 ttccagcaga agctgtcggg cagccacaag gcactggtgg agatgcagga 1150

 tgtcgtggct gagcttctga ggaccgtccc ctgggagcag ccggccacta 1200

 aggaccccct cctccgcgtc caggaggtgc tgaatggcac ggaggtgaac 1250

 ctgcagcacc tcaccgccct ggtggactgc cgcagcctgc atctggacta 1300

 cgtgcaagcg ctgaccggct tctgctatga cggcgtggag ggcctcatct 1350

 acctggccct cttctccttc gtcacagccc tcatgttcag ctccatcgtc 1400

 tgcagcgtcc cgcacacctg gcagcaaaag agaggccctg atgaggacgg 1450

 ggaggaggag gccgctccag ggccgcggca ggcgcacgac agcctctacc 1500

 gcgtccacat gcccagcctg tacagctgtg gcagcagcta cggcagtgag 1550

 accagcatcc cggccgcggc ccacaccgtc agcaacgccc cggtcactga 1600

 gtacatgagc cagaacgcta atttccagaa cccccgctgt gagaacaccc 1650

 cactcattgg gcgcgagtcc ccgccgccct catacacctc cagcatgaga 1700

 gccaaatacc tcgccacgag ccagcctcgc cctgactcca gcggcagcca 1750

 ctagaccgcg cccggcagcc acccacccca cgtgccaact tcccctcccc 1800

 gtgccagcac tgccgcttcc acctgggcca cccaccggac cctcgcacgc 1850

 cgtgccaggc ctgccccaga cgcgtctgca ggccgcttgc cctcctgtcc 1900

 cctccccgca ggggcacagt ggagacgcag gggctctggg cccgtaccgc 1950

 caactcgggt cacacctgaa cgctgctgcc agccgatgcc ccagccctgc 2000

 acgccaccca ctatcccggc acgctccctc tgcagatggt cgccgcacct 2050

 acaagccctg gccgcaccca acctgtgttg ttgccgcccg gcccttccct 2100

 ccacagctct ccttcctccc gcccggcact tctgtggacc ccttcttagt 2150

 tcacaggcac ggctggggcc gctctgtgct ggcgcctgct ggccactgag 2200

 ggacagggac acgtgccacc tgctcatctc tgccctgagg tcaccccgtg 2250

 gtccctccac gtgcccatct ctctgcagtg ccctcctcgc ctgtgcagcc 2300

 cgcccaccca caggctcacc cctcctgccg gctgccagag gccccctcca 2350

 gcagggcctc tctccgttgc cccagcttca ctctctccct cagcacctgc 2400

 cctgctggag gccccagccc tccgtggaca gcaggggcca cgtggagccc 2450

 gggccgctca cccgccaccc agtgctggcc gccttcttgg tgccaaaccc 2500

 ccttccccca cccagagact gggcagctgt gtctggttcg ttctttgcac 2550

 taaccacatt tgtcatctct agggcaggct ggggctgcgg gctgaggggg 2600

 accgctggca ccccccttcc ctcccttctt ggttccattt ccatccatga 2650

 caggtacagc atcccaggag cccggcctga ggggctggac ccgagctggc 2700

 tgtgaacatc cctcagcccc tgctgtcccc ccttgggact aaccactaac 2750

 ctcaccccca aactccacgg gtgcccctag ctggcccaga gccggcagtg 2800

 tgagcccaag tccgggctgg agccgaggcc ggagcagctg tctgggagtc 2850

 aaggctgcag tagcgtttct tcatggggtg ctccaggggg tgccacagac 2900

 cgacaggcag cccaagggcc tggacacccc tccccaggca ggtgctgccc 2950

 caggaggact gtcctcggga atgaacctcc cgcgggcttt ggactgaggt 3000

 ccctgtggcc tcggtctcct ccccatgaag tgggagcgag gctccccaat 3050

 ggtgcttttg gctttagtgt acgatgtttg ctgtgcttcc cgccgtggag 3100

 ggcagagcca ccccacatca ggatcggacg tgctacccct cccggtcccg 3150

 gccctggccc agccagccca gccctcgagg ctcgatgcct gtgccaaggc 3200

 caggggcagc cagagggcag ctggatggcc acgtgcaggg gtcaaggctg 3250

 ggccctgcag tggggcgggc cgccagcccc agcagtttac agacgcatgg 3300

 ctcttcctcc cagagcagcc ggcagctacc tggaccggaa atgtcctcat 3350

 cccctccctg gggccaggct ctgccctggc cttcctctgt gaacccctcc 3400

 tttctttgtg ctggtgtctg ggaccaaaaa gggggaatat gggagggcag 3450

 agtggggagg ggagtccatg ggcctggggc cccaagccgg ggcgtctgag 3500

 ctccccaggc atgaccaaac ctcagtggag gggcctctgc ttcaggcccc 3550

 gcctggctga cattctgagc ccccctcgga ggccccgcca cagccaacct 3600

 gcccagtctt tcctctgggc ttgacccgcc aggggagttc tccaggccta 3650

 gggccaggag agaggccctg gcaccctggc gtgggtgccc gccaaacgcc 3700

 ctgcgaccgc tcagaagcac aaatgctgtc catggccgtg aggctgcctg 3750

 ccaggtgaat ggacatagcg tgagaggcgg tgaggccagg gcttccagcc 3800

 tcgtgctgtc tcgggactcc tgaccgtggt gtgcgtgtgt gcccgtctgt 3850

 gactttctac tcaccaaggt tgaagaaagg aaacggggaa aatcaaaagg 3900

 ggttcaaacc ccacctcagt aggtggaggg gagcgcctgc cattggttgt 3950

 atttttgttc tgagttttcg gtgccgtgtt cctaactact ccatcccatg 4000

 acctcgccac acctactggg gcatctggct ggtgcctgct gccatggcca 4050

 gcccccactc tcaccctgca cagggggtct tgcagccccc aggcccacag 4100

 cctcgttggg aggacagggt ggccctgggg acaagaggga ggagcccagg 4150

 ggcttacctc actgagagtg ctccccagca ggcatccact accccagggc 4200

 cccccacatg tcatggcaag gttggtagtg aatgggcctg gttgggagca 4250

 gcccctggcc cattgcccac ccacccatct cactatgcaa ttcgagttcc 4300

 aagcaacatt tgctcctgcc ctggggccag ctctgcccca gccctgagag 4350

 gggtggtgag gcagccccct ggaccccaga accccagaca agggggcagg 4400

 cgggggacca gggcctctcc tgtgggatct ttgttttgtg tttaaccata 4450

 atggttgtgt actgaaccac ttcatatttg ttatatataa tatatatata 4500

 tataatctcc ttaagactca gcctcctggt ttaccccccc ggcctgggca 4550

 tctgacctcc cccaccccag tgtgatttaa catccaggaa ctgaggcctg 4600

 aaccattttg catttccccc tcctccagcc tctgtagggc catggctgta 4650

 tgtactgtcg ctgtgttttt ttgttttttt agaactgggt ttgggggctg 4700

 atttttattt ctttgggggc ttttttttct tggcaaatac taaaaatctc 4750

 gtcaatgtaa tttctgtggt ttctattcag cttgggtttc atgttttaaa 4800

 ataaatttta aaaagc 4816

<210> 4054
<211> 439
<212> PRT
<213> Homo sapien

<400> 4054
 Cys Thr Ala Trp Cys Val Ile Ile Ala Thr Leu Val Cys Ser Ala
   1               5                  10                  15

 Gly Ile Ala Val Gly Phe Tyr Gly Asn Gly Glu Thr Ser Asp Gly
                  20                  25                  30

 Ile His Arg Ala Thr Tyr Ser Leu Arg His Ala Asn Arg Thr Val
                  35                  40                  45

 Ala Gly Val Gln Asp Arg Val Trp Asp Thr Ala Val Gly Leu Asn
                  50                  55                  60

 His Thr Ala Glu Pro Ser Leu Gln Thr Leu Glu Arg Gln Leu Ala
                  65                  70                  75

 Gly Arg Pro Glu Pro Leu Arg Ala Val Gln Arg Leu Gln Gly Leu
                  80                  85                  90

 Leu Glu Thr Leu Leu Gly Tyr Thr Ala Ala Ile Pro Phe Trp Arg
                  95                 100                 105

 Asn Thr Ala Val Ser Leu Glu Val Leu Ala Glu Gln Val Asp Leu
                 110                 115                 120

 Tyr Asp Trp Tyr Arg Trp Leu Gly Tyr Leu Gly Leu Leu Leu Leu
                 125                 130                 135

 Asp Val Ile Ile Cys Leu Leu Val Leu Val Gly Leu Ile Arg Ser
                 140                 145                 150

 Ser Lys Gly Ile Leu Val Gly Val Cys Leu Leu Gly Val Leu Ala
                 155                 160                 165

 Leu Val Ile Ser Trp Gly Ala Leu Gly Leu Glu Leu Ala Val Ser
                 170                 175                 180

 Val Gly Ser Ser Asp Phe Cys Val Asp Pro Asp Ala Tyr Val Thr
                 185                 190                 195

 Lys Met Val Glu Glu Tyr Ser Val Leu Ser Gly Asp Ile Leu Gln
                 200                 205                 210

 Tyr Tyr Leu Ala Cys Ser Pro Arg Ala Ala Asn Pro Phe Gln Gln
                 215                 220                 225

 Lys Leu Ser Gly Ser His Lys Ala Leu Val Glu Met Gln Asp Val
                 230                 235                 240

 Val Ala Glu Leu Leu Arg Thr Val Pro Trp Glu Gln Pro Ala Thr
                 245                 250                 255

 Lys Asp Pro Leu Leu Arg Val Gln Glu Val Leu Asn Gly Thr Glu
                 260                 265                 270

 Val Asn Leu Gln His Leu Thr Ala Leu Val Asp Cys Arg Ser Leu
                 275                 280                 285

 His Leu Asp Tyr Val Gln Ala Leu Thr Gly Phe Cys Tyr Asp Gly
                 290                 295                 300

 Val Glu Gly Leu Ile Tyr Leu Ala Leu Phe Ser Phe Val Thr Ala
                 305                 310                 315

 Leu Met Phe Ser Ser Ile Val Cys Ser Val Pro His Thr Trp Gln
                 320                 325                 330

 Gln Lys Arg Gly Pro Asp Glu Asp Gly Glu Glu Glu Ala Ala Pro
                 335                 340                 345

 Gly Pro Arg Gln Ala His Asp Ser Leu Tyr Arg Val His Met Pro
                 350                 355                 360

 Ser Leu Tyr Ser Cys Gly Ser Ser Tyr Gly Ser Glu Thr Ser Ile
                 365                 370                 375

 Pro Ala Ala Ala His Thr Val Ser Asn Ala Pro Val Thr Glu Tyr
                 380                 385                 390

 Met Ser Gln Asn Ala Asn Phe Gln Asn Pro Arg Cys Glu Asn Thr
                 395                 400                 405

 Pro Leu Ile Gly Arg Glu Ser Pro Pro Pro Ser Tyr Thr Ser Ser
                 410                 415                 420

 Met Arg Ala Lys Tyr Leu Ala Thr Ser Gln Pro Arg Pro Asp Ser
                 425                 430                 435

 Ser Gly Ser His


<210> 4055
<211> 6607
<212> DNA
<213> Homo sapien

<400> 4055
 gacaaaggga ttttagtctt tcagttgaag aggaggccac cagaccacat 50

 cccaaagaaa accaagaaac acttggaagg caagacaccc aagggaaagg 100

 agagagctga cgggtctggc tatggctcca cccttcctcc ggagaagctg 150

 ccctatttag tagagttaag cccagggaga aggaatcact ttgcctacta 200

 caactatcac acttacgaag atggttctga ctctagagat aagccaaagc 250

 tttaccgcct tcagttaagt gttactgaag ttgggacaga aaagttggat 300

 gacaactcta tccagttgtt tggcccagga attcagcccc atcactgtga 350

 ccttaccaac atggatggag tggtcactgt gacgcccaga agtatggacg 400

 cagaaaccta cgtggaaggc cagcgcatct cagaaaccac catgctgcag 450

 agtggcatga aagtgcagtt tggggcgtcc catgtattta agtttgtgga 500

 ccccagtcag gatcatgctc ttgcaaaaag atctgtggat ggaggcctga 550

 tggttaaggg cccaagacat aaacctggaa ttgttcagga gacaactttt 600

 gatttgggag gagatattca tagtgggaca gcattaccga caagcaagag 650

 caccactagg ctggacagcg acagagtgtc gtctgcctct agcacagccg 700

 agcggggaat ggtgaagccg atgatcagag tagaacagca gccagattat 750

 cgcaggcaag aaagcagaac acaggatgct tctgggcctg aactgatact 800

 acctgcaagc attgaattca gggaaagttc tgaagattca tttttgtctg 850

 ccattataaa ttatactaat agctctacag tccactttaa gttgtcccct 900

 acatatgtat tatatatggc atgccggtat gtattgtcca accagtacag 950

 acctgacatc agccctacag agcgcacaca taaagtcatt gcagtcgtca 1000

 acaagatggt gagcatgatg gagggtgtca tccagaaaca gaagaatatt 1050

 gcaggggcac ttgccttctg gatggcaaat gcatctgaac ttctcaactt 1100

 cattaagcaa gaccgagacc ttagtcggat cacactggat gctcaagatg 1150

 ttttagcaca tttggttcaa atggcattta aatacttggt tcactgtctt 1200

 caatcagaac ttaataatta catgccagcc tttctagatg accctgaaga 1250

 gaacagtctg caacgaccaa aaatagatga tgtgctgcac acgctcacag 1300

 gagccatgtc cttgctacga cgctgcagag tcaatgccgc cctgaccatc 1350

 cagctcttct ctcagctctt ccacttcatc aatatgtggc tgttcaatag 1400

 attggtgacc gacccagatt cggggctgtg ctcccattac tggggtgcga 1450

 ttatccgtca gcagttgggc catattgaag cctgggctga gaagcagggg 1500

 ctggaactgg ctgcggactg tcatctgagc aggatcgtgc aggcaacgac 1550

 tttgcttacc atggataagt atgcacctga tgacattcca aatataaaca 1600

 gcacctgctt taagttaaat tcattacaac ttcaagcctt attacagaac 1650

 tatcactgtg cacctgatga gccttttatc ccaacggatc ttatagaaaa 1700

 tgtagtgact gtggctgaaa acactgccga tgagctggcc cgcagtgatg 1750

 gaagggaagt gcagttggag gaggatcctg atctgcagct gccgtttctt 1800

 ttgccagaag atggttattc ttgtgatgtt gtcagaaaca ttccaaatgg 1850

 tttacaagaa tttttagacc ctctgtgcca gagaggattt tgcaggttaa 1900

 ttcctcacac acgttcacca ggtacttgga caatatattt tgaaggtgca 1950

 gattatgaaa gtcaccttct gcgtgagaac acagagctgg ctcagcctct 2000

 gaggaaagaa cctgaaataa tcactgtgac cctaaaaaag cagaatggaa 2050

 tgggccttag cattgttgca gcaaagggtg ctggtcaaga taaactagga 2100

 atctacgtga agtcggttgt gaaaggaggt gctgcagatg tggatggacg 2150

 tctagctgca ggtgatcagc tcctcagtgt ggatggacga agtctggttg 2200

 gactctctca ggaaagggcg gcagaactca tgacaagaac aagctctgtg 2250

 gtgacactgg aagtagcaaa gcagggtgcc atctaccacg gtctggccac 2300

 ccttctcaat cagccatccc ccatgatgca gagaatttca gatcgtcgtg 2350

 gctcaggtaa accccgacca aagagtgaag gctttgagct ctataataat 2400

 tcaactcaaa atgggtctcc tgagagtcct cagctgcctt gggcagaata 2450

 tagtgaacca aagaaattgc ctggtgatga cagactgatg aaaaatagag 2500

 ctgatcaccg ttccagcccc aacgtagcaa atcagcctcc tagtcctgga 2550

 gggaaaagtg catatgcctc tggaacaaca gcgaagataa catctgtctc 2600

 tactggaaac ctctgcactg aggagcagac gcctccgcct agacctgaag 2650

 cctaccccat ccccactcag acgtacacca gagagtattt taccttccca 2700

 gcttccaaat cccaggatcg gatggctcct cctcagaacc agtggccaaa 2750

 ttatgaggaa aagccacata tgcacacaga tagtaatcat tccagtattg 2800

 caattcagcg tgttacacgt tcccaagaag aacttcgaga agataaagct 2850

 taccaacttg agcggcatcg aatagaggca gctatggacc gaaagtctga 2900

 tagtgatatg tggataaatc agagctcctc actggactcc agtacctcta 2950

 gccaggagca tctgaaccat tcctctaagt cggtcacccc tgcttccaca 3000

 ctgaccaaaa gtggccctgg ccgttggaaa acaccagcag ccataccggc 3050

 cacccctgtg gccgtctccc agccaatccg aacagacctg cctccgccac 3100

 ccccgccacc tccagtccac tatgccggtg atttcgatgg aatgtccatg 3150

 gatttgcctc tcccaccacc cccttccgcc aaccagatag ggctgccgtc 3200

 tgcgcaggtg gctgctgctg aacggagaaa gagagaagaa catcagcgtt 3250

 ggtatgagaa ggagaaggcc cgcctggagg aggagcggga gaggaagcgg 3300

 agagagcagg agaggaagtt gggccagatg cgcactcagt ccttaaaccc 3350

 tgctccgttt tctcccctga ctgcacagca gatgaagccc gaaaagcctt 3400

 ccacactcca gcggccacag gaaacagtca ttcgggagct gcagcctcag 3450

 cagcagcccc gcacgatcga gcgcagagac ttgcagtaca ttacagtcag 3500

 caaagaggag ctttcctcgg ggacagtctg tccccccgac ccgtggaagc 3550

 gggacgccaa ggagaagctg gagaagcagc agcagatgca catcgtggac 3600

 atgctgagca aggagatcca ggagctccag agcaaaccgg accgcagcgc 3650

 cgaggagagc gaccggctgc gcaagctcat gctggagtgg cagttccaga 3700

 agagactcca ggagtcgaag cagaaggacg aagatgacga ggaggaggag 3750

 gacgatgatg tggacaccat gctgatcatg cagcgcctgg aggctgaacg 3800

 aagagcgagg actgctatgc cagcaatctc tgttctagat ttgttgcagg 3850

 acgaggagcg gaggcggcag cagcagttag aagagatgcg caagcgggaa 3900

 gcggaagacc gagcgaggca agaggaagag cgccggcggc aggaggagga 3950

 gcgaacaaaa cgagacgctg aagaaaagag gcgacaggaa gaagggtatt 4000

 acagccgcct ggaagccgag aggcgcagac agcacgacga ggcggcgcgc 4050

 aggttgctgg agcccgaggc gcccggtctg tgccgccctc cgcttccccg 4100

 ggactacgag cccccgtccc cgtcccccgc ccggcgcccc tcctcccccg 4150

 cctcagcgaa acgcctccta cctcaaaaca caggtcctct cccccgactc 4200

 gctgttcact gccaagtttg ttgcatacaa tgaggaggag gaggaggagg 4250

 actgcagcct agcaggacca aactcttacc caggatctac tggagcagct 4300

 gttggagccc atgacgcctg tcgggatgca aaagagaagc gctctaaaag 4350

 ccaagatgca gattcacctg gaagttctgg ggcccctgaa aacttgacat 4400

 tcaaggaacg ccagcgtctt ttttcacaag gtcaagatgt atccaataaa 4450

 gtgaaagctt ctcgtaaatt aacagaactg gagaatgaac tgaacacaaa 4500

 gtgaaagaaa atgaggagaa cactttgtat ttaccccaaa atcttttcag 4550

 ttgtgggttt gtaggtgcga gtttgaagag gaaaagagga agggggttat 4600

 atttctaagt gatttacaat ttctgtttct aaaattgttg ggatttagaa 4650

 atgtttcaat tccaagaaat tttattttac tttaccatga gattgccatt 4700

 tatgtaattt aaacactgtc tagtttctta attatctaac tcacacgagg 4750

 gtaagttttt tgttggtttc ttttttggag tcctgagttc aaaggggaca 4800

 gaactaaggg caggagaaga gaatggatgt gtcttctctc ccatcttccc 4850

 ctcatcatcg accgaggagc acaaagaagt tctgtttctg tttttttcag 4900

 aaactttatt ttagctgtca agcagagaat agcttgaact attcagacta 4950

 ttgttggcac tgtttagtag tgaccacacg ctcttctacc cgggaaggaa 5000

 catatgacga catgctcctc ccatgtcccc tgatggtgtc tgttcccaca 5050

 atatccttct agtctgcatc gtgaagtggc ttaggccaaa gcttcctgtg 5100

 tgatgacgca cgtccgagac tgttccatct cattcctcgc aaatttgagc 5150

 tcttctgatc aattctaaat atttgattaa ttttaattct gaaagaaaat 5200

 tttgaggatt taagcttagg ggattttatt tttataaata ccagattatt 5250

 gttagactta ataaatcact gttaaattta aagatgacag ttaccttgga 5300

 aagttcacta atacttcgct ccaaggcgtc tgtaaaagaa gatatcttta 5350

 ttggagcaat gttcatgtga ctgggaatga cagaagaatg ggagatgagt 5400

 agggacccct caagcacagc tgtcactcag aaattttaaa tttgaaaaag 5450

 aaatcgattt tcatctgtat gccgtcaagg aaggaattca gttacagggc 5500

 atctgtaact taaatattgt aagaataact catatggaag ttcaagctat 5550

 ttttatacta taatagagtt atttaatttt aatttgttga attattagtt 5600

 accactgtca tttcttcagc tatggatatg tggctgatgt tggggagacg 5650

 gacctcagtg tgttttatat tgtctggtgt taagatgata aattactttg 5700

 tgattacaag caaattttct atttgacaaa gcccttggtg gagtccaaat 5750

 gatttttctg taccatattg ttctcttaca catacgtatg ttaggaaaat 5800

 aggcacactt tcaaagagaa tgttctctta cacatacgta tgttaggaaa 5850

 atagacacat tttcaaagag aatgttctct tacatatgtt aggaaaatag 5900

 gcacactttc aaagagaggt ataggggctt tttactgcct tcgaaatcac 5950

 ttttaataaa agttgtatga taaatcatta aaaatgcgag tgtaaatatt 6000

 tttttttacc tctatcaggg tttttatttg acagtgtgct cttaccattt 6050

 ccttgtttga gtaagagagt gaatggttct gagtgtttag gaaggatttg 6100

 cttgcttgca gcagaagttc taggaaaagc aggcacctcc caaatatctt 6150

 gaggacactg gcagccttat ggtgactaaa tccacacttt ctttaaagag 6200

 atgcagatga attacttttc tgttaatata tagaaaaata cacaggagaa 6250

 catgcagata catgtaaata tctacataca gggatatttg tatgtgtggt 6300

 tgtgaaaccc atacacaagt ggatttggcc atctttgggc agtgaggtca 6350

 aatgtgaata tgtgtaaaag tgcttttcag aactgcatta ctatgagaaa 6400

 acatcaaaac tgctgtagtt ttccatttct actgtatttc agttgcaacc 6450

 tatttttaat aaactttgta tgtatttaag tgtatttgct attgttttga 6500

 aagtgctgac aaagtttata tttgtaacat cagccttcct cgcccatctc 6550

 tttccatctg tctcttcttc attaaacact tactgagtac aaaaaaaaaa 6600

 aaaaaaa 6607

<210> 4056
<211> 5742
<212> DNA
<213> Homo sapien

<400> 4056
 gcgcggggct gagccgcccg ggatcagcgc gagcacccag cccgcctcgg 50

 ccgggagggc ctgagaaccc cgggggcgtg ctgagcgtgg agctgcccgg 100

 gctgctggcg cagctggcgc ggagcttcgc gctgctgctg cccgtgtacg 150

 cgctgggcta cctggggctc agcttcagct gggttctcct cgcgctcgcg 200

 ctgctcgcct ggtgtcgccg cagccgcggc ctcaaggccc tgcgcctgtg 250

 ccgcgcgctg gcgctgctgg aagacgagga gcgcgtcgtg cgcctggggg 300

 tgcgcgcctg cgacctgccc gcctgggttc attttccaga cactgaaaga 350

 gcagaatggc taaataagac tgtaaaacac atgtggcctt tcatttgcca 400

 atttatagag aagttgtttc gagaaactat agaaccagcc gtgcggggag 450

 caaacaccca ccttagcacc tttagtttca cgaaggtcga cgtgggccag 500

 cagcccctca ggatcaatgg tgttaaggta tacactgaaa atgtagacaa 550

 aaggcaaatt attttggacc ttcagattag ttttgtagga aattgtgaga 600

 ttgatttgga gatcaaacga tatttttgta gagctggtgt gaaaagtatc 650

 cagattcatg gtaccatgcg ggtgatcctg gaaccgttga ttggagatat 700

 gcccttagtt ggagctttgt ctatcttctt ccttaggaaa ccacttttag 750

 aaattaactg gacaggactg acgaatcttc tggatgtccc tggattgaat 800

 ggtttatcag atactatcat tttggatata atatcaaact atctggtgct 850

 tcccaatcga atcaccgttc cacttgtcag tgaagttcaa atagctcagt 900

 tgcggtttcc tgtaccaaag ggtgttctaa ggatacattt tattgaagct 950

 caggatcttc aggggaaaga cacttacctt aagggacttg tcaagggaaa 1000

 gtcagacccc tatggaatca ttagagttgg caaccaaatc ttccaaagca 1050

 gagtcatcaa ggagaacctc agtccaaagt ggaatgaagt ctatgaggct 1100

 ttagtgtatg aacatcctgg acaagaatta gagattgagc tctttgatga 1150

 agacccagac aaggatgact ttttaggaag tcttatgatt gacctcattg 1200

 aagttgaaaa ggagcgcctt ttagatgaat ggttcactct ggacgaggtt 1250

 cccaagggga agctacactt gagactggag tggctcacgt taatgccaaa 1300

 tgcgtcaaac ctcgacaagg tgctaacaga catcaaagct gacaaagacc 1350

 aagccaacga tggtctttcc tctgcattgc tgatcttgta cttggattca 1400

 gcaaggaacc ttccgtcagg gaagaaaata agcagcaacc caaatcctgt 1450

 tgtccagatg tcagttgggc acaaggccca ggagagcaag attcgataca 1500

 aaaccaatga acctgtgtgg gaggaaaact tcactttctt cattcacaat 1550

 cccaagcgcc aggaccttga agttgaggtc agagacgagc agcaccagtg 1600

 ttccctgggg aacctgaagg tccccctcag ccagctgctc accagtgagg 1650

 acatgactgt gagccagcgc ttccagctca gtaactcggg tccaaacagc 1700

 accatcaaga tgaagattgc cctgcgggtg ctccatctcg aaaagcgaga 1750

 aaggcctcca gaccaccaac actcagctca agtcaaacgt ccctctgtgt 1800

 ccaaagaggg gaggaaaaca tccatcaaat ctcatatgtc tgggtctcca 1850

 ggccctggtg gcagcaacac agctccatcc acaccagtca ttgggggcag 1900

 tgataagcct ggtatggaag aaaaggccca gccccctgag gccggccctc 1950

 aggggctgca cgacctgggc agaagctcct ccagcctcct ggcctcccca 2000

 ggccacatct cagtcaagga gccgaccccc agcatcgcct cggacatctc 2050

 gctgcccatc gccacccagg agctgcggca aaggctgagg cagctggaaa 2100

 acgggacgac cctgggacag tctccactgg ggcagatcca gctgaccatc 2150

 cggcacagct cgcagagaaa caagcttatc gtggtcgtgc atgcctgcag 2200

 aaacctcatt gccttctctg aagacggctc tgacccctat gtccgcatgt 2250

 atttattacc agacaagagg cggtcaggaa ggaggaaaac acacgtgtca 2300

 aagaaaacat taaatccagt gtttgatcaa agctttgatt tcagtgtttc 2350

 gttaccagaa gtccagagga gaacgcttga cgttgccgtg aagaacagtg 2400

 gcggcttcct gtccaaagac aaagggctcc ttggcaaagt attggttgct 2450

 ctggcatctg aagaacttgc caaaggctgg acccagtggt atgacctcac 2500

 ggaagatggg acgaggcctc aggcgatgac atagccgcag caggcaggag 2550

 gcgtcctctt cagcgtagct ctccacctct acccggaaca caccctctca 2600

 cagacgtacc aatgttattt ttataatttc atggatttag ttatacatac 2650

 cttaatagtt ttataaaatt gttgacattt caggcaaatt tggccaatat 2700

 tatcattgaa ttttctgtgt tggatttcct ctaggatttc gccagttcct 2750

 acaacgtgca gtagggcggc ggtagctctt gtgtctgtgg actctgctca 2800

 gctgtgtccg taggagtcgg atgtgtctgt gctttattat ggccttgttt 2850

 atatatcact gaggtatact atgccatgta aatagactat tttttataat 2900

 ctttacatgc tggtttaaat tcagaaggaa atagatcaag gaaatatata 2950

 tattttcttc taaaacttat taaattcgtg tgacaaataa tcattttcat 3000

 cttggcagca aaagttctca gtgacctatt ttgtggtgtt tctttttgaa 3050

 aagaaaagct gaaatattat taaatgctag tatgtttctg cccattatga 3100

 aagatgaaat aaagtattca aaatattaac attttcataa atataaggat 3150

 gtattattga gaagtaagtt gaagggctta taaggaaaaa tgttttataa 3200

 ctgagtaata tattaagaga attgtcatgg ttcataaatc acattatgct 3250

 aatctgaaat ttcttacata aaaatgaagt gtcttatgtt tattttaatt 3300

 gctgttgtaa cttactcatg aaacagtata cagacacctt gtacttttcc 3350

 tcaactgtaa gagcagactt tcaatgttag caattaagct gttgtcaaac 3400

 aatcagtcat gagctttgtt aattttcaat gttttcccag cctataaaaa 3450

 aaggaaggta cacgttgtcc ttttaaaggt tgtgaggtag attggagtga 3500

 gtagacagga tattgcatta aaaattgaaa gctcgatctc attattgtca 3550

 ggaaccccca gtgtgacctc acacatagga tgtgggacct ttgagccgat 3600

 gtgcactggc caccaccagg gttgggggcg ccacagctgc gagcccggcc 3650

 cctgctgttc tcagcagcca cttcccaggc tgcctcactt tatgccatga 3700

 ctgaccttaa tattgggata ttgttatgca atttttatcc tgtttagact 3750

 gttaaaagca ggtttctgta cttaagagtc ccccagacct cctgtgaggt 3800

 gaggctctgt tgcagtgtcg taggctgtgt gtgtctgtaa agaaagaatg 3850

 cacatatgta gacgattaag tgtatattat aagctatatg ctgaaaatgg 3900

 cttccatagc catgagaaca tcttaaaact atgtgtaaat atattaagga 3950

 aagtatagct ttgtaattta aattggagct tttagcttgt ttcatggaac 4000

 tatacaactt gtgggtaact cacatgacca aacaaaccaa agtgcctgtg 4050

 acggggcggg tggcgtctac ccaccctccc ttctagcaga ttcttatttt 4100

 gtttgaattt ataaacaagg ctggtggctg tctacccacc ctcccttcta 4150

 gcagattttg attttgtttc aatttataac ttacactttg aaccatgggt 4200

 ttacttataa tggagtctgt agcttcacag catatttcat gtaatcataa 4250

 agaccagtat attccctcct gctgaatgac atgcgactgt aaagcctctt 4300

 tataaaccat ttccaatgtt agtatatagg attatttggg aagcgtatca 4350

 atacctttat agacaaatac gaacatgtat gcacacaaaa catttaacta 4400

 tggtatttat ggaagacagg taacaacatt aaatctagtt gctttccctt 4450

 agtattagat ttgttgaggg ttttttaaaa atcaggtctg ttgaaagtct 4500

 tctgtcataa tctataaagc agcagcactc atggaaattg tagcatgcca 4550

 gtaattttta ccaacatccc atacatctga gttctgcagt ccagtgtgta 4600

 atccgctcca tgtgtatttt gcttaatgga atgctttatt taagcactta 4650

 ggcagagtag acacaattaa aggtacaaag cccagaggaa gtggtagagc 4700

 agcaccgtgc ctgccctgag gcagtggagt cagtagcgct gtccccaggg 4750

 ccttgagtgc ctggaggtgc ttggcctcca gtagctgcct ccattctctt 4800

 ttaaaaaaag ggggtgattc tgaggcactg aagtgcctcc cagatgtgga 4850

 ggagtgaagc caccatcgag gccacactca gcactccagg atcccagcga 4900

 tgtcagacac tcttgagttg tcaaaacgtt aattttcagt tttaaataat 4950

 cagtttatct aagaaaaggg aattttaact tttctacctt gagccaagcc 5000

 aatgaaggga aaattaatta acttagtaaa tttgaagtgc agctctgtta 5050

 gctcgtacat gtgggttctt atcctgatcc tgtgccttaa agtaggaagg 5100

 tgtttccaag ttcagattaa aatagaagca gctggccggg tgcggtggct 5150

 cacgcctgta atcccagcac tttgggaggc cgaggcgggc ggatgacctg 5200

 aggtcaggag ttcaagacca gcctggccaa catggagaaa ccccatcttt 5250

 actaaaaata caaaaattag ccgggcgtgg tggtggagcg cacgcctgta 5300

 gtcccagcta ctcgggaggc tgaggcagga gaattgcttg aacccaggag 5350

 gcggaggttg cagtgagcca agatcgcacc actgcactcc agcctgggca 5400

 acagagtgag actccgtctc aaaaaataaa taaaatagaa gcagccttgt 5450

 aactgtattt accatgataa tatattctgc acggtaagaa ttccttttac 5500

 agacattctt tatcaagagg tcggcccttc tttttcaggc acataagcca 5550

 aatgcaggcc tgtgtgtagc tgtgtgtttt ttctgtggtt gccgcattta 5600

 ttccacctcc agctggaccc cccactgcaa atagagaaca gcggtggggg 5650

 atgggggtta aaaagtagag aacctccttt ctgttcaact aatttcacgt 5700

 gacagtgcat gtatttattc aataaaacct ttatgttagc tc 5742

<210> 4057
<211> 843
<212> PRT
<213> Homo sapien

<400> 4057
 Ala Gly Leu Ser Arg Pro Gly Ser Ala Arg Ala Pro Ser Pro Pro
   1               5                  10                  15

 Arg Pro Gly Gly Pro Glu Asn Pro Gly Gly Val Leu Ser Val Glu
                  20                  25                  30

 Leu Pro Gly Leu Leu Ala Gln Leu Ala Arg Ser Phe Ala Leu Leu
                  35                  40                  45

 Leu Pro Val Tyr Ala Leu Gly Tyr Leu Gly Leu Ser Phe Ser Trp
                  50                  55                  60

 Val Leu Leu Ala Leu Ala Leu Leu Ala Trp Cys Arg Arg Ser Arg
                  65                  70                  75

 Gly Leu Lys Ala Leu Arg Leu Cys Arg Ala Leu Ala Leu Leu Glu
                  80                  85                  90

 Asp Glu Glu Arg Val Val Arg Leu Gly Val Arg Ala Cys Asp Leu
                  95                 100                 105

 Pro Ala Trp Val His Phe Pro Asp Thr Glu Arg Ala Glu Trp Leu
                 110                 115                 120

 Asn Lys Thr Val Lys His Met Trp Pro Phe Ile Cys Gln Phe Ile
                 125                 130                 135

 Glu Lys Leu Phe Arg Glu Thr Ile Glu Pro Ala Val Arg Gly Ala
                 140                 145                 150

 Asn Thr His Leu Ser Thr Phe Ser Phe Thr Lys Val Asp Val Gly
                 155                 160                 165

 Gln Gln Pro Leu Arg Ile Asn Gly Val Lys Val Tyr Thr Glu Asn
                 170                 175                 180

 Val Asp Lys Arg Gln Ile Ile Leu Asp Leu Gln Ile Ser Phe Val
                 185                 190                 195

 Gly Asn Cys Glu Ile Asp Leu Glu Ile Lys Arg Tyr Phe Cys Arg
                 200                 205                 210

 Ala Gly Val Lys Ser Ile Gln Ile His Gly Thr Met Arg Val Ile
                 215                 220                 225

 Leu Glu Pro Leu Ile Gly Asp Met Pro Leu Val Gly Ala Leu Ser
                 230                 235                 240

 Ile Phe Phe Leu Arg Lys Pro Leu Leu Glu Ile Asn Trp Thr Gly
                 245                 250                 255

 Leu Thr Asn Leu Leu Asp Val Pro Gly Leu Asn Gly Leu Ser Asp
                 260                 265                 270

 Thr Ile Ile Leu Asp Ile Ile Ser Asn Tyr Leu Val Leu Pro Asn
                 275                 280                 285

 Arg Ile Thr Val Pro Leu Val Ser Glu Val Gln Ile Ala Gln Leu
                 290                 295                 300

 Arg Phe Pro Val Pro Lys Gly Val Leu Arg Ile His Phe Ile Glu
                 305                 310                 315

 Ala Gln Asp Leu Gln Gly Lys Asp Thr Tyr Leu Lys Gly Leu Val
                 320                 325                 330

 Lys Gly Lys Ser Asp Pro Tyr Gly Ile Ile Arg Val Gly Asn Gln
                 335                 340                 345

 Ile Phe Gln Ser Arg Val Ile Lys Glu Asn Leu Ser Pro Lys Trp
                 350                 355                 360

 Asn Glu Val Tyr Glu Ala Leu Val Tyr Glu His Pro Gly Gln Glu
                 365                 370                 375

 Leu Glu Ile Glu Leu Phe Asp Glu Asp Pro Asp Lys Asp Asp Phe
                 380                 385                 390

 Leu Gly Ser Leu Met Ile Asp Leu Ile Glu Val Glu Lys Glu Arg
                 395                 400                 405

 Leu Leu Asp Glu Trp Phe Thr Leu Asp Glu Val Pro Lys Gly Lys
                 410                 415                 420

 Leu His Leu Arg Leu Glu Trp Leu Thr Leu Met Pro Asn Ala Ser
                 425                 430                 435

 Asn Leu Asp Lys Val Leu Thr Asp Ile Lys Ala Asp Lys Asp Gln
                 440                 445                 450

 Ala Asn Asp Gly Leu Ser Ser Ala Leu Leu Ile Leu Tyr Leu Asp
                 455                 460                 465

 Ser Ala Arg Asn Leu Pro Ser Gly Lys Lys Ile Ser Ser Asn Pro
                 470                 475                 480

 Asn Pro Val Val Gln Met Ser Val Gly His Lys Ala Gln Glu Ser
                 485                 490                 495

 Lys Ile Arg Tyr Lys Thr Asn Glu Pro Val Trp Glu Glu Asn Phe
                 500                 505                 510

 Thr Phe Phe Ile His Asn Pro Lys Arg Gln Asp Leu Glu Val Glu
                 515                 520                 525

 Val Arg Asp Glu Gln His Gln Cys Ser Leu Gly Asn Leu Lys Val
                 530                 535                 540

 Pro Leu Ser Gln Leu Leu Thr Ser Glu Asp Met Thr Val Ser Gln
                 545                 550                 555

 Arg Phe Gln Leu Ser Asn Ser Gly Pro Asn Ser Thr Ile Lys Met
                 560                 565                 570

 Lys Ile Ala Leu Arg Val Leu His Leu Glu Lys Arg Glu Arg Pro
                 575                 580                 585

 Pro Asp His Gln His Ser Ala Gln Val Lys Arg Pro Ser Val Ser
                 590                 595                 600

 Lys Glu Gly Arg Lys Thr Ser Ile Lys Ser His Met Ser Gly Ser
                 605                 610                 615

 Pro Gly Pro Gly Gly Ser Asn Thr Ala Pro Ser Thr Pro Val Ile
                 620                 625                 630

 Gly Gly Ser Asp Lys Pro Gly Met Glu Glu Lys Ala Gln Pro Pro
                 635                 640                 645

 Glu Ala Gly Pro Gln Gly Leu His Asp Leu Gly Arg Ser Ser Ser
                 650                 655                 660

 Ser Leu Leu Ala Ser Pro Gly His Ile Ser Val Lys Glu Pro Thr
                 665                 670                 675

 Pro Ser Ile Ala Ser Asp Ile Ser Leu Pro Ile Ala Thr Gln Glu
                 680                 685                 690

 Leu Arg Gln Arg Leu Arg Gln Leu Glu Asn Gly Thr Thr Leu Gly
                 695                 700                 705

 Gln Ser Pro Leu Gly Gln Ile Gln Leu Thr Ile Arg His Ser Ser
                 710                 715                 720

 Gln Arg Asn Lys Leu Ile Val Val Val His Ala Cys Arg Asn Leu
                 725                 730                 735

 Ile Ala Phe Ser Glu Asp Gly Ser Asp Pro Tyr Val Arg Met Tyr
                 740                 745                 750

 Leu Leu Pro Asp Lys Arg Arg Ser Gly Arg Arg Lys Thr His Val
                 755                 760                 765

 Ser Lys Lys Thr Leu Asn Pro Val Phe Asp Gln Ser Phe Asp Phe
                 770                 775                 780

 Ser Val Ser Leu Pro Glu Val Gln Arg Arg Thr Leu Asp Val Ala
                 785                 790                 795

 Val Lys Asn Ser Gly Gly Phe Leu Ser Lys Asp Lys Gly Leu Leu
                 800                 805                 810

 Gly Lys Val Leu Val Ala Leu Ala Ser Glu Glu Leu Ala Lys Gly
                 815                 820                 825

 Trp Thr Gln Trp Tyr Asp Leu Thr Glu Asp Gly Thr Arg Pro Gln
                 830                 835                 840

 Ala Met Thr


<210> 4058
<211> 1613
<212> DNA
<213> Homo sapien

<400> 4058
 agcgccgcgt ggttagcgtc ggcggctttt ggcatggcga ctttttctgg 50

 cccggctggg ccaatcctgt cgcttaatcc gcaggaagat gtcgagtttc 100

 aaaaggaggt ggcgcaggtt cgcaagcgca taacccagcg aaaaaaacaa 150

 gaacaactta ctcctggagt agtctatgtg cgccacctac ctaacctact 200

 tgacgaaacc cagatctttt catatttctc ccagtttggc actgtgacac 250

 ggttcaggct gtccagaagt aaaaggactg gaaatagcaa aggctatgca 300

 tttgtggagt ttgagtctga ggatgttgcc aaaatagttg ctgaaacaat 350

 gaacaactac ctgtttggtg aaagactctt ggagtgtcat tttatgccac 400

 ctgaaaaagt acataaagaa ctctttaaag actggaatat tccatttaag 450

 cagccatcat atccatcagt gaaacggtat aatcggaatc ggacactaac 500

 acaaaagcta cggatggagg agcgatttaa aaagaaagaa agattactca 550

 ggaagaaatt agctaaaaaa ggaattgact atgattttcc ttctttgatt 600

 ttacagaaaa cggaaagtat ttcaaaaact aatcgtcaga cgtctacaaa 650

 aggccaggtt ttacgtaaga agaagaaaaa agtttcaggt actcttgaca 700

 ctcctgagaa gactgtggat agccagggcc ccacaccagt ttgtacacca 750

 acatttttgg agaggcgaaa atctcaagtg gctgaactga atgatgatga 800

 taaagatgat gaaatagttt tcaaacagcc catatcctgt gtaaaagaag 850

 aaatacaaga gactcaaaca cctacacatt cacggaaaaa aagacgaaga 900

 agcagcaatc agtgattttc aatgtattat atttcttttg aaaaatataa 950

 tatttttatg agagtggact ttgtatttca ctaggtacaa tggaatacaa 1000

 cctttgacaa gattttcaga ggaaaaatac actgtttggt caagttaagg 1050

 aaagcagtgt gtaattttgg attgcctgcc cttggctgaa atacaggggt 1100

 gcataccatc ttgcagtggc ttggctgaca ttgcctctct gtcctggcct 1150

 ctagttttct tttgatattt catagctctc cttagtttac tctgcctgga 1200

 tagaaagttg accactaact gcaggtttaa gtactaaact gcagcctttt 1250

 ctgtcgccag caattaaaga ccaccaatct tgtttgtcca tctacatggt 1300

 ttgtcgggga catttaactc atggaggtgc tttagatttc aacatcagat 1350

 ggttgaagct ggaagtttaa ttatatgtag agtgagaagg cagttccagt 1400

 tttagcacag atttgtttat gtgttcagat tttaatagag attcaaaaat 1450

 gactcatttt taccaataat gttaaattag ttttggttgt gctagcatga 1500

 attaataacc accattttat accagtatca tcagtgaaga attgtatttc 1550

 aagattcaaa caataaccag caattaaact tttttctaca atgtaaaaaa 1600

 aaaaaaaaaa aaa 1613

<210> 4059
<211> 293
<212> PRT
<213> Homo sapien

<400> 4059
 Met Ala Thr Phe Ser Gly Pro Ala Gly Pro Ile Leu Ser Leu Asn
   1               5                  10                  15

 Pro Gln Glu Asp Val Glu Phe Gln Lys Glu Val Ala Gln Val Arg
                  20                  25                  30

 Lys Arg Ile Thr Gln Arg Lys Lys Gln Glu Gln Leu Thr Pro Gly
                  35                  40                  45

 Val Val Tyr Val Arg His Leu Pro Asn Leu Leu Asp Glu Thr Gln
                  50                  55                  60

 Ile Phe Ser Tyr Phe Ser Gln Phe Gly Thr Val Thr Arg Phe Arg
                  65                  70                  75

 Leu Ser Arg Ser Lys Arg Thr Gly Asn Ser Lys Gly Tyr Ala Phe
                  80                  85                  90

 Val Glu Phe Glu Ser Glu Asp Val Ala Lys Ile Val Ala Glu Thr
                  95                 100                 105

 Met Asn Asn Tyr Leu Phe Gly Glu Arg Leu Leu Glu Cys His Phe
                 110                 115                 120

 Met Pro Pro Glu Lys Val His Lys Glu Leu Phe Lys Asp Trp Asn
                 125                 130                 135

 Ile Pro Phe Lys Gln Pro Ser Tyr Pro Ser Val Lys Arg Tyr Asn
                 140                 145                 150

 Arg Asn Arg Thr Leu Thr Gln Lys Leu Arg Met Glu Glu Arg Phe
                 155                 160                 165

 Lys Lys Lys Glu Arg Leu Leu Arg Lys Lys Leu Ala Lys Lys Gly
                 170                 175                 180

 Ile Asp Tyr Asp Phe Pro Ser Leu Ile Leu Gln Lys Thr Glu Ser
                 185                 190                 195

 Ile Ser Lys Thr Asn Arg Gln Thr Ser Thr Lys Gly Gln Val Leu
                 200                 205                 210

 Arg Lys Lys Lys Lys Lys Val Ser Gly Thr Leu Asp Thr Pro Glu
                 215                 220                 225

 Lys Thr Val Asp Ser Gln Gly Pro Thr Pro Val Cys Thr Pro Thr
                 230                 235                 240

 Phe Leu Glu Arg Arg Lys Ser Gln Val Ala Glu Leu Asn Asp Asp
                 245                 250                 255

 Asp Lys Asp Asp Glu Ile Val Phe Lys Gln Pro Ile Ser Cys Val
                 260                 265                 270

 Lys Glu Glu Ile Gln Glu Thr Gln Thr Pro Thr His Ser Arg Lys
                 275                 280                 285

 Lys Arg Arg Arg Ser Ser Asn Gln
                 290

<210> 4060
<211> 1782
<212> DNA
<213> Homo sapien

<400> 4060
 ggcacgaggg gcggcgtagg ggcggaggtc gcgcctgagt gcgtccgcac 50

 gagagggcgg aaccgtctcc atggcaaccc gcgcgcagcc ggggccactc 100

 agccaggcgg gaagcgctgg tgttgcggcg ctggcgacag tcggggttgc 150

 gagcggcccg gggccggggc ggccagggcc gctgcaggac gagaccctgg 200

 gtgtggcgtc cgtgccctcg cagtggaggg ccgtccaggg catccgcggg 250

 gagacgaaaa gttgccagac ggccagcatt gccactgcca gtgcatccgc 300

 ccaggccagg aatcatgtgg acgcccaggt gcagacggag gcccccgtgc 350

 ctgtcagcgt gcagcccccg tcccagtacg acatacccag gcttgcagcc 400

 tttcttcgga gagtggaggc catggtcatc cgagagctga acaagaattg 450

 gcagagccac gcgtttgatg gcttcgaggt gaactggacc gagcagcagc 500

 agatggtgtc ttgtctgtat accctgggct acccgccagc ccaagcgcag 550

 ggtctgcatg tgaccagcat ctcctggaac tccactggct ctgtggtggc 600

 ctgtgcctac ggccggctgg accatgggga ctggagcacg cttaagtcct 650

 tcgtgtgtgc ctggaacctg gaccggcgag acctgcgtcc ccagcaaccg 700

 tcggccgtgg tggaggtccc cagcgctgtc ctgtgtctgg ccttccaccc 750

 cacgcagccc tcccacgtcg caggagggct gtacagtggt gaggtgttgg 800

 tgtgggacct gagccgtctt gaggacccgc tgctgtggcg cacaggcctg 850

 acggatgaca cccacacaga ccctgtgtcc caggtggtgt ggctgcccga 900

 gcctgggcac agccaccgct tccaggtgct gagtgtggcc actgacggga 950

 aggtgctact ctggcagggc atcggggtag gccagctgca gctcacagag 1000

 ggcttcgccc tggtcatgca gcagctgcca cggagcacca agctcaagaa 1050

 gcatccccgc ggggagaccg aggtgggcgc cacggcagtg gccttctcca 1100

 gctttgaccc taggctgttc attctgggca cggaaggcgg cttcccgctc 1150

 aagtgttccc tggcagctgg agaggcagcc ctcacgcgga tgcccagctc 1200

 cgtgcccctg cgggccccag cacagtttac cttctccccc cacggcggtc 1250

 ccatctactc tgtgagctgt tcccccttcc acaggaatct cttcctgagc 1300

 gctgggactg acgggcatgt ccacctgtac tccatgctgc aggcccctcc 1350

 cttgacttcg ctgcagctct ccctcaagta tctgtttgct gtgcgctggt 1400

 ccccagtgcg gcccttggtt tttgcagctg cctctgggaa aggtgacgtg 1450

 cagctgtttg atctccagaa aagctcccag aaacccacag ttttgatcaa 1500

 gcaaacccag gatgaaagcc ctgtctactg tctggagttc aacagccagc 1550

 agactcagct cttggctgcg ggcgatgccc agggcacagt gaaggtgtgg 1600

 cagctgagca cagagttcac ggaacaaggg ccccgggaag ctgaggacct 1650

 ggactgcctg gcagcagagg tggcggcctg aggggtcccg ggaggcgggt 1700

 gcaagccttc gctgtgccga gccttgtgtt tctgacgcaa gccaaatgaa 1750

 gaaaagcaaa gcttaaaaaa aaaaaaaaaa aa 1782

<210> 4061
<211> 419
<212> PRT
<213> Homo sapien

<400> 4061
 Met Val Ile Arg Glu Leu Asn Lys Asn Trp Gln Ser His Ala Phe
   1               5                  10                  15

 Asp Gly Phe Glu Val Asn Trp Thr Glu Gln Gln Gln Met Val Ser
                  20                  25                  30

 Cys Leu Tyr Thr Leu Gly Tyr Pro Pro Ala Gln Ala Gln Gly Leu
                  35                  40                  45

 His Val Thr Ser Ile Ser Trp Asn Ser Thr Gly Ser Val Val Ala
                  50                  55                  60

 Cys Ala Tyr Gly Arg Leu Asp His Gly Asp Trp Ser Thr Leu Lys
                  65                  70                  75

 Ser Phe Val Cys Ala Trp Asn Leu Asp Arg Arg Asp Leu Arg Pro
                  80                  85                  90

 Gln Gln Pro Ser Ala Val Val Glu Val Pro Ser Ala Val Leu Cys
                  95                 100                 105

 Leu Ala Phe His Pro Thr Gln Pro Ser His Val Ala Gly Gly Leu
                 110                 115                 120

 Tyr Ser Gly Glu Val Leu Val Trp Asp Leu Ser Arg Leu Glu Asp
                 125                 130                 135

 Pro Leu Leu Trp Arg Thr Gly Leu Thr Asp Asp Thr His Thr Asp
                 140                 145                 150

 Pro Val Ser Gln Val Val Trp Leu Pro Glu Pro Gly His Ser His
                 155                 160                 165

 Arg Phe Gln Val Leu Ser Val Ala Thr Asp Gly Lys Val Leu Leu
                 170                 175                 180

 Trp Gln Gly Ile Gly Val Gly Gln Leu Gln Leu Thr Glu Gly Phe
                 185                 190                 195

 Ala Leu Val Met Gln Gln Leu Pro Arg Ser Thr Lys Leu Lys Lys
                 200                 205                 210

 His Pro Arg Gly Glu Thr Glu Val Gly Ala Thr Ala Val Ala Phe
                 215                 220                 225

 Ser Ser Phe Asp Pro Arg Leu Phe Ile Leu Gly Thr Glu Gly Gly
                 230                 235                 240

 Phe Pro Leu Lys Cys Ser Leu Ala Ala Gly Glu Ala Ala Leu Thr
                 245                 250                 255

 Arg Met Pro Ser Ser Val Pro Leu Arg Ala Pro Ala Gln Phe Thr
                 260                 265                 270

 Phe Ser Pro His Gly Gly Pro Ile Tyr Ser Val Ser Cys Ser Pro
                 275                 280                 285

 Phe His Arg Asn Leu Phe Leu Ser Ala Gly Thr Asp Gly His Val
                 290                 295                 300

 His Leu Tyr Ser Met Leu Gln Ala Pro Pro Leu Thr Ser Leu Gln
                 305                 310                 315

 Leu Ser Leu Lys Tyr Leu Phe Ala Val Arg Trp Ser Pro Val Arg
                 320                 325                 330

 Pro Leu Val Phe Ala Ala Ala Ser Gly Lys Gly Asp Val Gln Leu
                 335                 340                 345

 Phe Asp Leu Gln Lys Ser Ser Gln Lys Pro Thr Val Leu Ile Lys
                 350                 355                 360

 Gln Thr Gln Asp Glu Ser Pro Val Tyr Cys Leu Glu Phe Asn Ser
                 365                 370                 375

 Gln Gln Thr Gln Leu Leu Ala Ala Gly Asp Ala Gln Gly Thr Val
                 380                 385                 390

 Lys Val Trp Gln Leu Ser Thr Glu Phe Thr Glu Gln Gly Pro Arg
                 395                 400                 405

 Glu Ala Glu Asp Leu Asp Cys Leu Ala Ala Glu Val Ala Ala
                 410                 415

<210> 4062
<211> 583
<212> DNA
<213> Homo sapien

<400> 4062
 ggcacgaggc gttgggaacg gttgtaggac gtggctcttt attcgtgagt 50

 tttccattta cctccgctga acctagagct tcagacgccc tatggcgtcc 100

 gcctcgaccc aaccggcggc cttgagcgct gagcaagcaa aggtggtcct 150

 cgcggaggtg atccaggcgt tctccgcccc ggagaatgca gtgcgcatgg 200

 acgaggctcg ggataacgcc tgcaacgaca tgggtaagat gctgcaattc 250

 gtgctgcccg tggccacgca gatccagcag gaggttatca aagcctatgg 300

 cttcagctgc gacggggaag gtgtccttaa gtttgctcgc ttggtcaagt 350

 cctacgaagc ccaggatcct gagatcgcca gcctgtcagg caagctgaag 400

 gcgctgtttc tgccgcccat gaccctgcca ccccatgggc ctgctgctgg 450

 tggcagcgtg gccgcctcct gagagttggc cctcccttgt gccactgcca 500

 ggggaggaaa ggccttgatg ttccagacaa taataaatgc gcctgtgact 550

 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 583

<210> 4063
<211> 126
<212> PRT
<213> Homo sapien

<400> 4063
 Met Ala Ser Ala Ser Thr Gln Pro Ala Ala Leu Ser Ala Glu Gln
   1               5                  10                  15

 Ala Lys Val Val Leu Ala Glu Val Ile Gln Ala Phe Ser Ala Pro
                  20                  25                  30

 Glu Asn Ala Val Arg Met Asp Glu Ala Arg Asp Asn Ala Cys Asn
                  35                  40                  45

 Asp Met Gly Lys Met Leu Gln Phe Val Leu Pro Val Ala Thr Gln
                  50                  55                  60

 Ile Gln Gln Glu Val Ile Lys Ala Tyr Gly Phe Ser Cys Asp Gly
                  65                  70                  75

 Glu Gly Val Leu Lys Phe Ala Arg Leu Val Lys Ser Tyr Glu Ala
                  80                  85                  90

 Gln Asp Pro Glu Ile Ala Ser Leu Ser Gly Lys Leu Lys Ala Leu
                  95                 100                 105

 Phe Leu Pro Pro Met Thr Leu Pro Pro His Gly Pro Ala Ala Gly
                 110                 115                 120

 Gly Ser Val Ala Ala Ser
                 125

<210> 4064
<211> 2318
<212> DNA
<213> Homo sapien

<400> 4064
 gtgtgtgtgt gtgtgtgtgt gagagagaga gatgtgttgg ggtgggggga 50

 ctgcaggtca ggaagtcctg cagatgtgcg tgcctgtgtg tgtttgcgcg 100

 cgcgcgcgcg tgtgtgtgtg tctgtgtgtg tgcctggagc tgcgcttgca 150

 ggtctgagag tcctctgaga atgggttggg ggaggcgggt gcaggaccga 200

 ggcctggaac agccaacaaa gaggccctgg aggagggtgg ggctggccgg 250

 ggacaggagg ggtggccaag aaagtcgcaa gaaaactccg gcccccaaga 300

 aaaagagagg gcatgggttg cggagccgac atcacggccg gggtctttgc 350

 tgtttagacg cctgggttcc cggatcccag acacgcgcac gggcaggaag 400

 ttagaccgga gacagcgagt atagacagcc cttctggata ggggcagacg 450

 gcccgggttt ccgcttccct ccgggcgcga gaagagggga gccaggccga 500

 gccccggccc taccgccgcc gccgccatgt ggcccccaga ccccgacccc 550

 gacccggacc ccgagcctgc cggcggctcc cgtcccggcc ccgcggtccc 600

 cgggctccgc gccctgctgc cggcgcgggc tttcctctgc tctctcaaag 650

 gccgcctcct gctggccgag tcgggtctct cattcatcac ttttatctgc 700

 tatgtggcgt cctcagcatc tgccttcctc acagcgcctc tgctggagtt 750

 cctgctggcc ttgtacttcc tctttgctga tgccatgcag ctgaatgaca 800

 agtggcaggg cttgtgctgg cccatgatgg acttcctgcg ctgtgtcacc 850

 gcggccctca tctactttgc tatctccatc acggccatcg ccaagtactc 900

 ggatggggct tccaaagccg ctggggtgtt tggcttcttt gctaccatcg 950

 tgtttgcaac tgatttctac ctgatcttta acgacgtggc caaattcctc 1000

 aaacaagggg actctgcaga tgagaccaca gcccacaaga cagaagaaga 1050

 gaattccgac tcggactctg actgaaggcc tggcgggtgc cttggcaacc 1100

 tgagccacac aggcctccac ccctgcgcct cacaggggtc gctggcgttg 1150

 gagcggaggc ctggacttct gagttgcaga gggggctgcg gacacagcag 1200

 gccccctaca gcctcaggtt ctgcctgagc ccagcctacc aggcttgccc 1250

 ctcagctcag cactgttgac cacgctgcgt atgagggcat cttgggtatc 1300

 ccactccttc tccccatttc tgtcccacag gccttcagcc ctttaacgtc 1350

 tctgccaaaa accagcacaa ggagacaaag cagagccttg tctgtatctg 1400

 ggcagcaggt gttccatgct gctaggtggc gggggtcggg ggtcttctgt 1450

 ttcactaaca ggaacaaaga cagaaaccat gacagggctg ccccgccagg 1500

 ccccggtggg tttgtctgca cttggtgctc ctgcccacac cagccacttt 1550

 ggtgacaatg acccttccaa gaatctttgg ttcaaggagc accagttccc 1600

 tcttcattct tgaagcaggg agaaattgac ctttgccttg tcgcccagga 1650

 agtggggctc ggcacccata actaacacct cccacccttg gaaaccatgt 1700

 cttctggggg tgagatgacc attctgggtc taagactgtt tcaaagaaga 1750

 gctcatagac tgactggtcc agaagacaga gggtacaaca gtggcatcac 1800

 agtgacagtg tcatggggag ctgggcgggc ccagccaaac cctccttctt 1850

 cctagagccc agccagcagg caggagttcc tggaccctca ggacagtgaa 1900

 cttccagacc tcagggcagg tctatgggcc actgcaggag atgagaccag 1950

 ccttctgtgt tcacctaacg atttatactg tgtatctgtc tttgatggaa 2000

 ttttgtaact ttttatattt ttttatgcaa aagcagcttc ttaacagatg 2050

 gcattttctg tgactctagg cctcacaaaa gagccagagt tctggaccca 2100

 tgtttggagc atttgtagcc ttattctctt gcgtgtgaat ctcttaccct 2150

 gaaaaaaagc cataatgaat taagccagac tgaccacttg cttggagtgt 2200

 gtgcttgaaa aaaccagagc aatactgttg ggtattgtat caggcttcag 2250

 tacaaactgg taacaccaat gtggatcctg acagctttca gttttagcaa 2300

 aaatacacgt gaaatctg 2318

<210> 4065
<211> 182
<212> PRT
<213> Homo sapien

<400> 4065
 Met Trp Pro Pro Asp Pro Asp Pro Asp Pro Asp Pro Glu Pro Ala
   1               5                  10                  15

 Gly Gly Ser Arg Pro Gly Pro Ala Val Pro Gly Leu Arg Ala Leu
                  20                  25                  30

 Leu Pro Ala Arg Ala Phe Leu Cys Ser Leu Lys Gly Arg Leu Leu
                  35                  40                  45

 Leu Ala Glu Ser Gly Leu Ser Phe Ile Thr Phe Ile Cys Tyr Val
                  50                  55                  60

 Ala Ser Ser Ala Ser Ala Phe Leu Thr Ala Pro Leu Leu Glu Phe
                  65                  70                  75

 Leu Leu Ala Leu Tyr Phe Leu Phe Ala Asp Ala Met Gln Leu Asn
                  80                  85                  90

 Asp Lys Trp Gln Gly Leu Cys Trp Pro Met Met Asp Phe Leu Arg
                  95                 100                 105

 Cys Val Thr Ala Ala Leu Ile Tyr Phe Ala Ile Ser Ile Thr Ala
                 110                 115                 120

 Ile Ala Lys Tyr Ser Asp Gly Ala Ser Lys Ala Ala Gly Val Phe
                 125                 130                 135

 Gly Phe Phe Ala Thr Ile Val Phe Ala Thr Asp Phe Tyr Leu Ile
                 140                 145                 150

 Phe Asn Asp Val Ala Lys Phe Leu Lys Gln Gly Asp Ser Ala Asp
                 155                 160                 165

 Glu Thr Thr Ala His Lys Thr Glu Glu Glu Asn Ser Asp Ser Asp
                 170                 175                 180

 Ser Asp


<210> 4066
<211> 2126
<212> DNA
<213> Homo sapien

<400> 4066
 ggcgctccgc ctgctgcgcg tctacgcggt ccccgcgggc cttccgggcc 50

 cactgcgccg cgcggaccgc ctcgggctcg gacggccggt gtccccggcg 100

 cgccgctcgc ccggatcggc cgcggcttcg gcgcctgggg ctcggggctc 150

 cggggaggcc gtcgcccgcg atgctgctct ccaagttcgg ctccctggcg 200

 cacctctgcg ggcccggcgg cgtggaccac ctcccggtga agatcctgca 250

 gccagccaag gcggacaagg agagcttcga gaaggcgtac caggtgggcg 300

 ccgtgctggg tagcggcggc ttcggcacgg tctacgcggg tagccgcatc 350

 gccgacgggc tcccggtggc tgtgaagcac gtggtgaagg agcgggtgac 400

 cgagtggggc agcctgggcg gcgcgaccgt gcccctggag gtggtgctgc 450

 tgcgcaaggt gggcgcggcg ggcggcgcgc gcggcgtcat ccgcctgctg 500

 gactggttcg agcggcccga cggcttcctg ctggtgctgg agcggcccga 550

 gccggcgcag gacctcttcg actttatcac ggagcgcggc gccctggacg 600

 agccgctggc gcgccgcttc ttcgcgcagg tgctggccgc cgtgcgccac 650

 tgccacagct gcggggtcgt gcaccgcgac attaaggacg aaaatctgct 700

 tgtggacctg cgctccggag agctcaagct catcgacttc ggttcgggtg 750

 cgctgctcaa ggacacggtc tacaccgact tcgacggcac ccgagtgtac 800

 agccccccgg agtggatccg ctaccaccgc taccacgggc gctcggccac 850

 cgtgtggtcg ctgggcgtgc ttctctacga tatggtgtgt ggggacatcc 900

 ccttcgagca ggacgaggag atcctccgag gccgcctgct cttccggagg 950

 agggtctctc cagagtgcca gcagctgatc cggtggtgcc tgtccctgcg 1000

 gccctcagag cggccgtcgc tggatcagat tgcggcccat ccctggatgc 1050

 tgggggctga cgggggcgcc ccggagagct gtgacctgcg gctgtgcacc 1100

 ctcgaccctg atgacgtggc cagcaccacg tccagcagcg agagcttgtg 1150

 aggagctgca cctgactggg agctagggga ccacctgcct tggccagacc 1200

 tgggacgccc ccagaccctg actttttcct gcgtgggccg tctcctcctg 1250

 cggaagcagt gacctctgac ccctggtgac cttcgctttg agtgcctttt 1300

 gaacgctggt cccgcgggac ttggttttct caagctctgt ctgtccaaag 1350

 acgctccggt cgaggtcccg cctgccctgg gtggatactt gaaccccaga 1400

 cgcccctctg tgctgctgtg tccggaggcg gccttcccat ctgcctgccc 1450

 acccggagct ctttccgccg gcgcagggtc ccaagcccac ctcccgccct 1500

 cagtcctgcg gtgtgcgtct gggcacgtcc tgcacacaca atgcaagtcc 1550

 tggcytccgc gcccgcccgc ccacgcgagc cgtacccgcc gccaactctg 1600

 ttatttatgg tgtgaccccc tggaggtgcc ctcggcccac cggggctatt 1650

 tattgtttaa tttatttgtt gaggttattt cctctgagca gtctgcctct 1700

 cccaagcccc aggggacagt ggggaggcag gggagggggt ggctgtggtc 1750

 cagggacccc aggccctgat tcctgtgcct ggcgtctgtc ctggccccgc 1800

 ctgtcagaag atgaacatgt atagtggcta acttaagggg agtgggtgac 1850

 cctgacactt ccaggcactg tgcccagggt ttgggtttta aattattgac 1900

 tttgtacagt ctgcttgtgg gctctgaaag ctggggtggg gccagagcct 1950

 gagcgtttaa tttattcagt acctgtgttt gtgtgaatgc ggtgtgtgca 2000

 ggcatcgcag atgggggttc tttcagttca aaagtgagat gtctggagat 2050

 catatttttt tatacaggta tttcaattaa aatgtttttg tacatagaaa 2100

 aaaaaaaaaa aaaaaaaaaa gggcgg 2126

<210> 4067
<211> 382
<212> PRT
<213> Homo sapien

<400> 4067
 Arg Ser Ala Cys Cys Ala Ser Thr Arg Ser Pro Arg Ala Phe Arg
   1               5                  10                  15

 Ala His Cys Ala Ala Arg Thr Ala Ser Gly Ser Asp Gly Arg Cys
                  20                  25                  30

 Pro Arg Arg Ala Ala Arg Pro Asp Arg Pro Arg Leu Arg Arg Leu
                  35                  40                  45

 Gly Leu Gly Ala Pro Gly Arg Pro Ser Pro Ala Met Leu Leu Ser
                  50                  55                  60

 Lys Phe Gly Ser Leu Ala His Leu Cys Gly Pro Gly Gly Val Asp
                  65                  70                  75

 His Leu Pro Val Lys Ile Leu Gln Pro Ala Lys Ala Asp Lys Glu
                  80                  85                  90

 Ser Phe Glu Lys Ala Tyr Gln Val Gly Ala Val Leu Gly Ser Gly
                  95                 100                 105

 Gly Phe Gly Thr Val Tyr Ala Gly Ser Arg Ile Ala Asp Gly Leu
                 110                 115                 120

 Pro Val Ala Val Lys His Val Val Lys Glu Arg Val Thr Glu Trp
                 125                 130                 135

 Gly Ser Leu Gly Gly Ala Thr Val Pro Leu Glu Val Val Leu Leu
                 140                 145                 150

 Arg Lys Val Gly Ala Ala Gly Gly Ala Arg Gly Val Ile Arg Leu
                 155                 160                 165

 Leu Asp Trp Phe Glu Arg Pro Asp Gly Phe Leu Leu Val Leu Glu
                 170                 175                 180

 Arg Pro Glu Pro Ala Gln Asp Leu Phe Asp Phe Ile Thr Glu Arg
                 185                 190                 195

 Gly Ala Leu Asp Glu Pro Leu Ala Arg Arg Phe Phe Ala Gln Val
                 200                 205                 210

 Leu Ala Ala Val Arg His Cys His Ser Cys Gly Val Val His Arg
                 215                 220                 225

 Asp Ile Lys Asp Glu Asn Leu Leu Val Asp Leu Arg Ser Gly Glu
                 230                 235                 240

 Leu Lys Leu Ile Asp Phe Gly Ser Gly Ala Leu Leu Lys Asp Thr
                 245                 250                 255

 Val Tyr Thr Asp Phe Asp Gly Thr Arg Val Tyr Ser Pro Pro Glu
                 260                 265                 270

 Trp Ile Arg Tyr His Arg Tyr His Gly Arg Ser Ala Thr Val Trp
                 275                 280                 285

 Ser Leu Gly Val Leu Leu Tyr Asp Met Val Cys Gly Asp Ile Pro
                 290                 295                 300

 Phe Glu Gln Asp Glu Glu Ile Leu Arg Gly Arg Leu Leu Phe Arg
                 305                 310                 315

 Arg Arg Val Ser Pro Glu Cys Gln Gln Leu Ile Arg Trp Cys Leu
                 320                 325                 330

 Ser Leu Arg Pro Ser Glu Arg Pro Ser Leu Asp Gln Ile Ala Ala
                 335                 340                 345

 His Pro Trp Met Leu Gly Ala Asp Gly Gly Ala Pro Glu Ser Cys
                 350                 355                 360

 Asp Leu Arg Leu Cys Thr Leu Asp Pro Asp Asp Val Ala Ser Thr
                 365                 370                 375

 Thr Ser Ser Ser Glu Ser Leu
                 380

<210> 4068
<211> 1735
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 775-835
<223> Unknown base

<400> 4068
 gcagtgcatt tccaaccatg atccacgggt cttcacattc ataattcatc 50

 aggtcgggca accacctagc accatcttcc cgggcacagg gagcggagac 100

 ccggcctcaa ccacaaaccc caggccagca gcacagaccc aagaactgcg 150

 gactcctgtg aggtatggtg ctgggtgcag atgcagtgtg gctctggata 200

 gcaccttatg gacagttgtg tccccaagga aggatgagaa tagctactga 250

 agtcctaaag agcaagccta actcaagcca ttggcacaca ggcattagac 300

 agaaagctgg aagttgaaat ggtggagtcc aacttgcctg gaccagctta 350

 atggttctgc tcctggtaac gtttttatcc atggatgact tgcttgggta 400

 tggagagtcg gcttgactac actgtgtgga gcaagtttta aagaagcaaa 450

 ggactcagaa ttcatgattg aagaaatgca ggcagacctg ttatcctaaa 500

 ctagggtttt taatgaccac aacaagcaag catgcagctt actgcttgaa 550

 agggtcttgc ctcacccaag ctagagtgca gtggcctttg aagcttacta 600

 cagcctcaaa cttctgggct caaagtgatc ctcagcctcc cagtggtctt 650

 tgtagactgc ctgatggagt ctcatggcac aagaagatta aaacagtgtc 700

 tccaatttaa tcttcttgtg ccatgagact ccatcaggca gtctacaaag 750

 accactggga ggctgaggat cactnnnnnn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnaggca agaccctttc 850

 aagcagtaag ctgcatgctt gcttgttgtg gtcattaaaa accctgaaag 900

 cgaagccaac atattaatca gggcaaaata caaatgtgtg atgcttgtta 950

 gtagagtaac ctcagaatca aaatggaacg gttttacagt gatatcatta 1000

 tatttcattt ggcagaatca ttacatcatt ggttacactg aaaatcatca 1050

 catgtaccaa aagctgactc acctagttta ggataacagg tctgcctgtt 1100

 tgaagatgaa aaataatacc catttaaaat ttgccctact caatttcctt 1150

 ctcagtcaca ttttaacttt taaacagcta atcactccca tctacagatt 1200

 aaggtgtata tgccaccaaa accttttgcc accttaaaaa tttccttcaa 1250

 agtttaaact aacctgcatt tcttcaatca tgaattctga gtcctttgct 1300

 tctttaaaac ttgctccaca cagtgtagtc aagccgactc tccatacctg 1350

 tagaaattta atctccttta ccaataggta gtaataggtg gatttctaaa 1400

 agatttccca actactgttt cagtttaaga ttaatctcca ttttctttct 1450

 cagagagatt cccatctgct ttaattttaa aatcatcact aacagtagct 1500

 caatcaatta acgttaacat caataaaaca tataccttta aaaggtatga 1550

 caggaactat cttcatgtcc ttacccaagc aagtcatcca tggataaaaa 1600

 cgttaccagg agctggaata caaatgagga cttccattaa aatgctaaac 1650

 atcattaaac tcttttcaaa gttgtctgtc acagggttct tcagtgttac 1700

 ctttgtctac atgctcattt caggtcagac attga 1735

<210> 4069
<211> 82
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 775-835
<223> Unknown amino acid

<400> 4069
 Gln Cys Ile Ser Asn His Asp Pro Arg Val Phe Thr Phe Ile Ile
   1               5                  10                  15

 His Gln Val Gly Gln Pro Pro Ser Thr Ile Phe Pro Gly Thr Gly
                  20                  25                  30

 Ser Gly Asp Pro Ala Ser Thr Thr Asn Pro Arg Pro Ala Ala Gln
                  35                  40                  45

 Thr Gln Glu Leu Arg Thr Pro Val Arg Tyr Gly Ala Gly Cys Arg
                  50                  55                  60

 Cys Ser Val Ala Leu Asp Ser Thr Leu Trp Thr Val Val Ser Pro
                  65                  70                  75

 Arg Lys Asp Glu Asn Ser Tyr
                  80

<210> 4070
<211> 2516
<212> DNA
<213> Homo sapien

<400> 4070
 ggcacgaggg cagcgagtgg ccttcccggt tggcgcgcgc ccggggcggc 50

 ggcgctggag gagctcgaga cggagcctag ttatgtctgg gaggcgaacg 100

 cggtccggag gagccgctca gcgctccggg ccaagggccc catctcctac 150

 taagcctctg cggaggtccc agcggaaatc aggctctgaa ctcccgagca 200

 tcctccctga aatctggccg aagacaccca gtgcggctgc agtcagaaag 250

 cccatcgtct taaagaggat cgtggcccat gctgtagagg tcccagctgt 300

 ccaatcacct cgcaggagcc ctaggatttc ctttttcttg gagaaagaaa 350

 acgagccccc tggcagggag cttactaagg aggacctttt caagacacac 400

 agcgtccctg ccacccccac cagcactcct gtgccgaacc ctgaggccga 450

 gtccagctcc aaggaaggag agctggacgc cagagacttg gaaatgtcta 500

 agaaagtcag gcgttcctac agccggctgg agaccctggg ctctgcctct 550

 acctccaccc caggccgccg gtcctgcttt ggcttcgagg ggctgctggg 600

 ggcagaagac ttgtccggag tctcgccagt ggtgtgctcc aaactcaccg 650

 aggtccccag ggtttgtgca aagccctggg ccccagacat gactctccct 700

 ggaatctccc caccacccga gaaacagaaa cgtaagaaga agaaaatgcc 750

 agagatcttg aaaacggagc tggatgagtg ggctgcggcc atgaatgccg 800

 agtttgaagc tgctgagcag tttgatctcc tggttgaatg agatgcagtg 850

 gggggtgcac ctggccagac tctccctcct gtcctgtaca tagccacctc 900

 cctgtggaga ggacacttag ggtcccctcc cctggtcttg ttacctgtgt 950

 gtgtgctggt gctgcgcatg aggactgtct gcctttgagg gcttgggcag 1000

 cagcggcagc catcttggtt ttaggaaatg gggccgcctg gcccagccac 1050

 tcactggtgt cctgtctctt gtcgtcctgt ccttcctatc tccccaaagt 1100

 accatagcca gtttccagat gggccacaga ctggggagga gaatcagtgg 1150

 cccagccaga agttaaaggg ctgagggttg aggtgagagg cacctctgct 1200

 cttgttggga ggggtggctg cttggaaata ggcccagggg ctctgccagc 1250

 ctcggcctct ccctcctgag ttgccttctg ttggtggctt tcttcttgaa 1300

 cccacctgtg taaagaggtt ttcagttccg tgggtttccc ctttgattct 1350

 gtaaatagtc ccagagagaa ttcgtgggct gagggcaatt ctgtcttgga 1400

 ggaagaagct ggacattcag cctgtggagt ctgagttttg aaggatgtag 1450

 ggagccttag ttgggtctca gaccataagt gtgtactaca cagaagctgt 1500

 gttttctagt tctggtctgc tgttgagatg tttggtaaat gccaggttga 1550

 tagggcgctg gctgcttgga gcaaagggtg catttcaggg tgtggccacc 1600

 aggtgctgtg agtttctgtg gctcatggcc tctgggctgg tcccttgcac 1650

 agggcccacg ctggagtctt accactctgc tgcaggggtg gaaggtggcc 1700

 cctcttgtca cccataccca tttcttacaa aataagttac accgagtcta 1750

 cttggcccta gaagagaaag ttgaagagtc ccagacctac tagcattttg 1800

 caactatgct tgtaaagtcc tcggaaagtt tcctcgcgta ccagacagcg 1850

 gcgggggctg atagcaattt tagtttttgg cctccctatc ctctcacatg 1900

 agaacactgc ctggatgcat ctcatgatct ctggagaatt tccccatctt 1950

 tctcttcttt ccatcgtgtg gattcaatag tttggatttg aaggctgccc 2000

 tgcccccgac tctcctgccg cacccctggc cattgtacct tttgatgttt 2050

 agaagttcgt ggaagtagac gctgaggtgt gcagaggagc tggtggataa 2100

 cagagaatgc cagggaagat gagtgctggg tcagggtact tggatgaaac 2150

 ggtgcaggcc aggcgggccc taataaaacc ctctgccagg tctgggagtc 2200

 ccaggccatc tgctcaacgc tctgtggttt gtcagacctg caagcaagcc 2250

 ccctgctggg gaagcctagg tgtccttgag ctgaaccgca ctgaagaact 2300

 cttgtcctca ctggctgatg cagcagaact cttgggaaat gtcttagtcc 2350

 tgcagaatca ggagtcacca gatgatgcag agttgagatc atcattgcaa 2400

 agttctctgt tcctgaggaa ctaaatttaa ggaaaaaatg ggattttgtt 2450

 ttagagttgg aaaaaaagcc tgattaaaga gtttctgcct gttaaaaaaa 2500

 aaaaaaaaaa aaaaaa 2516

<210> 4071
<211> 252
<212> PRT
<213> Homo sapien

<400> 4071
 Met Ser Gly Arg Arg Thr Arg Ser Gly Gly Ala Ala Gln Arg Ser
   1               5                  10                  15

 Gly Pro Arg Ala Pro Ser Pro Thr Lys Pro Leu Arg Arg Ser Gln
                  20                  25                  30

 Arg Lys Ser Gly Ser Glu Leu Pro Ser Ile Leu Pro Glu Ile Trp
                  35                  40                  45

 Pro Lys Thr Pro Ser Ala Ala Ala Val Arg Lys Pro Ile Val Leu
                  50                  55                  60

 Lys Arg Ile Val Ala His Ala Val Glu Val Pro Ala Val Gln Ser
                  65                  70                  75

 Pro Arg Arg Ser Pro Arg Ile Ser Phe Phe Leu Glu Lys Glu Asn
                  80                  85                  90

 Glu Pro Pro Gly Arg Glu Leu Thr Lys Glu Asp Leu Phe Lys Thr
                  95                 100                 105

 His Ser Val Pro Ala Thr Pro Thr Ser Thr Pro Val Pro Asn Pro
                 110                 115                 120

 Glu Ala Glu Ser Ser Ser Lys Glu Gly Glu Leu Asp Ala Arg Asp
                 125                 130                 135

 Leu Glu Met Ser Lys Lys Val Arg Arg Ser Tyr Ser Arg Leu Glu
                 140                 145                 150

 Thr Leu Gly Ser Ala Ser Thr Ser Thr Pro Gly Arg Arg Ser Cys
                 155                 160                 165

 Phe Gly Phe Glu Gly Leu Leu Gly Ala Glu Asp Leu Ser Gly Val
                 170                 175                 180

 Ser Pro Val Val Cys Ser Lys Leu Thr Glu Val Pro Arg Val Cys
                 185                 190                 195

 Ala Lys Pro Trp Ala Pro Asp Met Thr Leu Pro Gly Ile Ser Pro
                 200                 205                 210

 Pro Pro Glu Lys Gln Lys Arg Lys Lys Lys Lys Met Pro Glu Ile
                 215                 220                 225

 Leu Lys Thr Glu Leu Asp Glu Trp Ala Ala Ala Met Asn Ala Glu
                 230                 235                 240

 Phe Glu Ala Ala Glu Gln Phe Asp Leu Leu Val Glu
                 245                 250

<210> 4072
<211> 7130
<212> DNA
<213> Homo sapien

<400> 4072
 cgctgtcccg gagccggcca gccccgtgcg gatccactcg ccccgcttcc 50

 tctggatctc tctaggagct gacactcgaa ccttcacgac ccattcggat 100

 ttttccagga ctcaggagtg gcactgggaa gaaggggacc gctttctgca 150

 attggcctcg acactggctg ccaagaagac ctgtcgcctt tgtttttaag 200

 tctccagaaa tggaagaaga aggcgaagtc agttgaagtc acgagaaatc 250

 agcgaggcat ttgaaggcgc ttcctgaaaa cctttattcc ctggcacgtt 300

 gtctgtttca acagccctgc ccctcctcgg agcctgcttg tggaattctt 350

 ccccttcggg tgtgtggtgg cattccccgc cacgtccaat gtggactcca 400

 aaggatttgt cccttctttg tcatttgaaa tgaaatgatg gccacgcgtc 450

 ggactggtct gtctgaggga gatggtgaca agctcaaggc ctgcgaggtc 500

 tcaaaaaata aagatggaaa agaacaaagt gaaactgtat cactgtctga 550

 agatgaaaca ttctcctggc caggtcccaa aacagttacg ttgaaaagaa 600

 catctcaagg ctttggtttt acattaagac attttattgt ttatccccca 650

 gagtctgcaa ttcaattttc atataaggat gaagaaaatg gaaacagagg 700

 aggaaaacaa agaaaccgct tggaaccaat ggataccata tttgttaagc 750

 aagttaaaga aggaggacct gcttttgaag ctggattatg tacaggtgac 800

 cgaattataa aagtcaatgg agaaagtgtt attggcaaaa cctattccca 850

 agtaattgct ttaattcaaa acagtgatac aacattggaa cttagtgtta 900

 tgccaaaaga tgaagacatt ctccaagtgc tacagtttac aaaggatgtc 950

 acagcactgg catattctca agatgcctac ctgaaaggca acgaagctta 1000

 tagcggcaat gcccgcaata tacctgaacc tccaccaatc tgctatccct 1050

 ggctgccatc tgccccatca gccatggcac agccagttga aatatctcct 1100

 cctgactcat cattgagcaa acagcaaacc agtacaccag tactgacaca 1150

 acctggtagg gcctatagaa tggaaataca agtgcctcca tcaccaacag 1200

 atgttgcaaa atcaaacaca gcagtgtgtg tttgcaatga aagtgtaagg 1250

 actgtcattg tgccttctga gaaggttgta gatttgttat ccaatagaaa 1300

 caaccataca ggtccttcac atagaactga agaagtgagg tatggcgtga 1350

 atgagcagac ctctttaaaa acagtgtcaa gaaccacatc accaccatta 1400

 tcaattccca ccactcatct aattcatcag cctgcaggct ccagatcact 1450

 ggaaccttct ggaattttac ttaagtctgg aaattacagt ggacattctg 1500

 atggaatctc aagcagcaga tctcaagctg tggaggctcc ctctgtatct 1550

 gttaatcact attcgccaaa ttcccatcag cacatagact ggaaaaacta 1600

 taaaacttac aaagagtata ttgataacag acgattgcac ataggttgtc 1650

 ggacaataca agaaagatta gatagtttaa gagcagcatc tcaaagcacg 1700

 acagattata accaggtcgt ccccaaccgc actactttgc agggacgacg 1750

 tcgaagcacc tctcatgatc gagtgcccca gtctgtccag atacggcaac 1800

 gcagtgtgtc ccaagaaaga ctggaagatt ctgtgctaat gaagtattgt 1850

 ccaagaagtg catctcaagg agcactgacg tctccatctg ttagttttag 1900

 taatcataga actcgttcat gggattatat tgagggacag gatgaaacct 1950

 tagaaaatgt caattctgga actccaatac ctgattccaa tggagagaaa 2000

 aaacagactt acaagtggag tgggtttact gaacaggatg atagacgagg 2050

 tatttgtgaa agacctaggc agcaagaaat tcataaatct tttcgaggtt 2100

 ccaattttac tgtggctcca agcgttgtta attctgataa caggcgaatg 2150

 agtggtagag gagtgggatc tgtgtcgcag tttaaaaaaa ttccaccaga 2200

 tctaaaaaca ttgcagtcaa acagaaattt tcagactact tgtggaatgt 2250

 cactgcctcg gggtatttca caagacaggt cacctcttgt gaaagtccga 2300

 agtaattctc tgaaagctcc ttccacgcat gtcacaaaac catcatttag 2350

 ccagaaatca tttgtttcta tcaaagacca aagaccagta aatcacttgc 2400

 atcagaacag tctgttgaat cagcagacat gggtaaggac tgacagtgcc 2450

 cccgatcagc aagtggagac tgggaaatcc ccctctttat ctggagcctc 2500

 tgccaagcct gcccctcagt cgagtgaaaa cgctggtact tcagatttag 2550

 aactacctgt cagtcaaagg agtcaagatt taagtttaca agaggctgaa 2600

 actgagcaat cagatacttt agataataaa gaagctgtca tcctaaggga 2650

 aaaacctcca tctggacgcc agacaccgca gcctttaagg catcagtctt 2700

 acatcttggc agtaaatgac caggagaccg ggtcagacac tacctgctgg 2750

 ctgcccaatg atgcacgtcg agaggtccac ataaaaagaa tggaggaaag 2800

 aaaagcctcg agtaccagtc cgcctggcga ttctttggct tccatcccat 2850

 ttatagatga accaactagc cctagcattg atcatgatat tgcacatatc 2900

 cctgcctctg ctgttatatc agcctctacc tctcaggtcc cctccatagc 2950

 aacagttcct ccttgcctca caacttcagc tccattaatt cgccgtcagc 3000

 tctcacatga ccacgaatct gttggccctc ctagcctgga tgctcagccc 3050

 aactcaaaga cagaaagatc aaaatcatat gatgagggtc tggatgatta 3100

 cagagaagat gcaaaattgt cctttaagca cgtacctagt ctgaagggaa 3150

 tcaagatcgc agacagccaa aagtcatcag aagactctgg gtccagaaaa 3200

 gattcttcct cagaggtctt cagtgatgct gccaaggaag ggtggcttca 3250

 tttccgaccc cttgtcaccg ataagggcaa gcgagttggt ggaagtattc 3300

 ggccatggaa acagatgtat gttgtccttc ggggtcattc actttacctg 3350

 tacaaagata aaagagagca gacgactccg tctgaggaag agcagcccat 3400

 cagtgttaat gcttgcttga tagacatctc ttacagtgag accaagagga 3450

 aaaatgtgtt tcgactcacc acgtccgact gtgaatgcct gtttcaggct 3500

 gaagacagag atgatatgct agcttggatc aagacgatcc aggagagcag 3550

 caacctaaac gaagaggaca ctggagtcac taacagggat ctaattagtc 3600

 gaagaataaa agaatacaac aatctgatga gcaaagcaga acagttgcca 3650

 aaaacacctc gccagagtct cagcatcagg caaactttgc ttggtgctaa 3700

 atcagagcca aagactcaaa gcccacactc tccgaaggaa gagtcggaaa 3750

 ggaaacttct cagtaaagat gataccagtc ccccaaaaga caaaggcaca 3800

 tggagaaaag gcattccaag tatcatgaga aagacatttg agaaaaagcc 3850

 aactgctaca ggaactttcg gcgtccgact agatgactgc ccaccagctc 3900

 atactaatcg gtatattcca ttaatagttg acatatgttg caaattagtt 3950

 gaagaaagag gtcttgaata tacaggtatt tatagagttc ctggaaataa 4000

 tgcagccatc tcaagtatgc aagaagaact caacaaggga atggctgata 4050

 ttgatataca agatgataaa tggcgagatt tgaatgtgat aagcagttta 4100

 ctaaaatcct tcttcagaaa actccctgag cctctcttca caaatgataa 4150

 atatgctgat tttattgaag ccaatcgtaa agaagatcct ctagatcgtc 4200

 tgaaaacatt aaaaagacta attcacgatt tgcctgaaca tcattatgaa 4250

 acacttaagt tcctttcagc tcatctgaag acagtggcag aaaattcaga 4300

 aaaaaataag atggaaccaa gaaacctagc aatagtgttt ggtcccaccc 4350

 ttgttcgaac atcagaagac aacatgaccc acatggtcac ccacatgcct 4400

 gaccagtaca agattgtaga aacgctcatc cagcaccatg actggttttt 4450

 cacagaagaa ggtgctgaag agcctcttac aacagtgcag gaggaaagca 4500

 cagtagactc ccagccagtg ccaaacatag atcatttact caccaacatt 4550

 ggaaggacag gagtctcccc aggagatgta tcagattcag ctactagtga 4600

 ctcaacaaaa tctaagggtt cttggggatc tggaaaggat cagtatagca 4650

 gggaactgct tgtgtcctcc atctttgcag ctgctagtcg caagaggaag 4700

 aagccgaaag aaaaagcaca gcctagcagc tcagaagatg aactggacaa 4750

 tgtatttttt aagaaagaaa atgtggaaca gtgtcacaat gatactaaag 4800

 aggagtccaa aaaagaaagt gagacactgg gcagaaaaca gaagatcatc 4850

 attgccaaag aaaacagcac taggaaagac cccagcacga caaaagatga 4900

 aaagatatca ctaggaaaag agagcacgcc ttctgaagaa ccctcaccac 4950

 cacacaactc aaaacacaac aagtcaccaa ctctcagctg tcgctttgcc 5000

 atcctgaaag agagccccag gtcacttctg gcacagaagt cctcccacct 5050

 tgaagagaca ggctctgact ctggcacttt gctcagcacg tcttcccagg 5100

 cctccctggc aaggttttcc atgaagaaat caaccagtcc agaaacgaaa 5150

 catagcgagt ttttggccaa cgtcagcacc atcacctcag attattccac 5200

 cacatcgtct gctacatact tgactagcct ggactccagt cgactgagcc 5250

 ctgaggtgca atccgtggca gagagcaagg gggacgaggc agatgacgag 5300

 agaagcgaac tcatcagtga agggcggcct gtggaaaccg acagcgagag 5350

 cgagtttccc gtgttcccca cagccttgac ttcagagagg cttttccgag 5400

 gaaaactgca agaagtgact aagagcagcc ggagaaattc tgaaggaagt 5450

 gaattaagtt gcaccgaggg aagtttaaca tcaagtttag atagccggag 5500

 acagctcttc agttcccata aactcatcga atgtgatact ctttccagga 5550

 aaaaatcagc tagattcaag tcagatagtg gaagtctagg agatgccaag 5600

 aatgagaaag aagcaccttc gttaactaaa gtgtttgatg ttatgaaaaa 5650

 aggaaagtca actgggagtt tactgacacc caccagaggc gaatccgaaa 5700

 aacaggaacc cacatggaaa acgaaaatag cagatcggtt aaaactgaga 5750

 cccagagccc ctgcggatga catgtttgga gcagggaatc acaaagtgaa 5800

 tgccgagact gctaaaagga aaagcatccg gcgcagacat acactaggag 5850

 ggcacagaga tgctaccgaa atcagcgttt tgaatttttg gaaagtgcat 5900

 gagcagagcg gggagagaga atctgaactt tcagctgtaa accggttaaa 5950

 accaaaatgc tcagcccagg acctttccat ctcagactgg ctggccaggg 6000

 aacgcctacg caccagtacc tctgacctta gcagaggaga aatcggagat 6050

 ccccagacag agaacccaag cacacgagaa atagccacga ccgacacacc 6100

 tttgtctctt cattgcaaca caggcagttc ttccagcacc ttggcttcaa 6150

 caaacaggcc ccttctttcc ataccaccac agtcacctga ccaaataaac 6200

 ggagaaagct tccagaacgt gagcaaaaat gctagttctg cagcgaatgc 6250

 ccaacctcat aaactgtctg aaaccccagg cactaaagca gagtttcatc 6300

 cctgtcttta aactgggggt atgtccactc tagcaagtaa aaaaactact 6350

 gttacacgtt ccagtaactc tgtcaatatt ttcttgtatc agaattgtta 6400

 ttatgcaggg ggcccccccc ccccttcatt tgggctggtt tcatcatttt 6450

 gcactgtgaa atagctttac agtgcattac tacagccaga agaacatata 6500

 tatatatata tatttaaaaa tatatcggat agttgtatac aaatgagcaa 6550

 ggtatttgtt gcaacttact acatagcata tacccaaaat cactgaagaa 6600

 aatcgctggc atcagtgtgc agcaaatttg ttcttttggt ttcatcacta 6650

 acaaaagtgc ctcatcataa aaatacagtt ggtttttagg gtgccatatt 6700

 gttaaaatta gataacttac ttacattgaa taaacgaatg cgttttattg 6750

 gtaacagata tcattacatt taccagtttt aacacaggtg gatacagaac 6800

 ttcccccaaa agtttttttt ttctttagtc attccaggtg gatctgagtt 6850

 ttatattcaa acttttaata cagtttttga gttttgtgtg acttgaattt 6900

 ttaatctttc tgtaaaatac gtaacttaaa tgaacatatt aaatgtgtat 6950

 cttttcttca gataccagat ttgatataat gttgtaacat aggtgtgtag 7000

 atagtggatc ctggatggaa ctggcttctt tatcgagaag aatataattc 7050

 tgcatgagga cttaatgaat ccaaacctgt gtcatgcctg tgtgcatacc 7100

 caattaaaca ctggaaataa aaaaaaaaaa 7130

<210> 4073
<211> 1957
<212> PRT
<213> Homo sapien

<400> 4073
 Met Ala Thr Arg Arg Thr Gly Leu Ser Glu Gly Asp Gly Asp Lys
   1               5                  10                  15

 Leu Lys Ala Cys Glu Val Ser Lys Asn Lys Asp Gly Lys Glu Gln
                  20                  25                  30

 Ser Glu Thr Val Ser Leu Ser Glu Asp Glu Thr Phe Ser Trp Pro
                  35                  40                  45

 Gly Pro Lys Thr Val Thr Leu Lys Arg Thr Ser Gln Gly Phe Gly
                  50                  55                  60

 Phe Thr Leu Arg His Phe Ile Val Tyr Pro Pro Glu Ser Ala Ile
                  65                  70                  75

 Gln Phe Ser Tyr Lys Asp Glu Glu Asn Gly Asn Arg Gly Gly Lys
                  80                  85                  90

 Gln Arg Asn Arg Leu Glu Pro Met Asp Thr Ile Phe Val Lys Gln
                  95                 100                 105

 Val Lys Glu Gly Gly Pro Ala Phe Glu Ala Gly Leu Cys Thr Gly
                 110                 115                 120

 Asp Arg Ile Ile Lys Val Asn Gly Glu Ser Val Ile Gly Lys Thr
                 125                 130                 135

 Tyr Ser Gln Val Ile Ala Leu Ile Gln Asn Ser Asp Thr Thr Leu
                 140                 145                 150

 Glu Leu Ser Val Met Pro Lys Asp Glu Asp Ile Leu Gln Val Leu
                 155                 160                 165

 Gln Phe Thr Lys Asp Val Thr Ala Leu Ala Tyr Ser Gln Asp Ala
                 170                 175                 180

 Tyr Leu Lys Gly Asn Glu Ala Tyr Ser Gly Asn Ala Arg Asn Ile
                 185                 190                 195

 Pro Glu Pro Pro Pro Ile Cys Tyr Pro Trp Leu Pro Ser Ala Pro
                 200                 205                 210

 Ser Ala Met Ala Gln Pro Val Glu Ile Ser Pro Pro Asp Ser Ser
                 215                 220                 225

 Leu Ser Lys Gln Gln Thr Ser Thr Pro Val Leu Thr Gln Pro Gly
                 230                 235                 240

 Arg Ala Tyr Arg Met Glu Ile Gln Val Pro Pro Ser Pro Thr Asp
                 245                 250                 255

 Val Ala Lys Ser Asn Thr Ala Val Cys Val Cys Asn Glu Ser Val
                 260                 265                 270

 Arg Thr Val Ile Val Pro Ser Glu Lys Val Val Asp Leu Leu Ser
                 275                 280                 285

 Asn Arg Asn Asn His Thr Gly Pro Ser His Arg Thr Glu Glu Val
                 290                 295                 300

 Arg Tyr Gly Val Asn Glu Gln Thr Ser Leu Lys Thr Val Ser Arg
                 305                 310                 315

 Thr Thr Ser Pro Pro Leu Ser Ile Pro Thr Thr His Leu Ile His
                 320                 325                 330

 Gln Pro Ala Gly Ser Arg Ser Leu Glu Pro Ser Gly Ile Leu Leu
                 335                 340                 345

 Lys Ser Gly Asn Tyr Ser Gly His Ser Asp Gly Ile Ser Ser Ser
                 350                 355                 360

 Arg Ser Gln Ala Val Glu Ala Pro Ser Val Ser Val Asn His Tyr
                 365                 370                 375

 Ser Pro Asn Ser His Gln His Ile Asp Trp Lys Asn Tyr Lys Thr
                 380                 385                 390

 Tyr Lys Glu Tyr Ile Asp Asn Arg Arg Leu His Ile Gly Cys Arg
                 395                 400                 405

 Thr Ile Gln Glu Arg Leu Asp Ser Leu Arg Ala Ala Ser Gln Ser
                 410                 415                 420

 Thr Thr Asp Tyr Asn Gln Val Val Pro Asn Arg Thr Thr Leu Gln
                 425                 430                 435

 Gly Arg Arg Arg Ser Thr Ser His Asp Arg Val Pro Gln Ser Val
                 440                 445                 450

 Gln Ile Arg Gln Arg Ser Val Ser Gln Glu Arg Leu Glu Asp Ser
                 455                 460                 465

 Val Leu Met Lys Tyr Cys Pro Arg Ser Ala Ser Gln Gly Ala Leu
                 470                 475                 480

 Thr Ser Pro Ser Val Ser Phe Ser Asn His Arg Thr Arg Ser Trp
                 485                 490                 495

 Asp Tyr Ile Glu Gly Gln Asp Glu Thr Leu Glu Asn Val Asn Ser
                 500                 505                 510

 Gly Thr Pro Ile Pro Asp Ser Asn Gly Glu Lys Lys Gln Thr Tyr
                 515                 520                 525

 Lys Trp Ser Gly Phe Thr Glu Gln Asp Asp Arg Arg Gly Ile Cys
                 530                 535                 540

 Glu Arg Pro Arg Gln Gln Glu Ile His Lys Ser Phe Arg Gly Ser
                 545                 550                 555

 Asn Phe Thr Val Ala Pro Ser Val Val Asn Ser Asp Asn Arg Arg
                 560                 565                 570

 Met Ser Gly Arg Gly Val Gly Ser Val Ser Gln Phe Lys Lys Ile
                 575                 580                 585

 Pro Pro Asp Leu Lys Thr Leu Gln Ser Asn Arg Asn Phe Gln Thr
                 590                 595                 600

 Thr Cys Gly Met Ser Leu Pro Arg Gly Ile Ser Gln Asp Arg Ser
                 605                 610                 615

 Pro Leu Val Lys Val Arg Ser Asn Ser Leu Lys Ala Pro Ser Thr
                 620                 625                 630

 His Val Thr Lys Pro Ser Phe Ser Gln Lys Ser Phe Val Ser Ile
                 635                 640                 645

 Lys Asp Gln Arg Pro Val Asn His Leu His Gln Asn Ser Leu Leu
                 650                 655                 660

 Asn Gln Gln Thr Trp Val Arg Thr Asp Ser Ala Pro Asp Gln Gln
                 665                 670                 675

 Val Glu Thr Gly Lys Ser Pro Ser Leu Ser Gly Ala Ser Ala Lys
                 680                 685                 690

 Pro Ala Pro Gln Ser Ser Glu Asn Ala Gly Thr Ser Asp Leu Glu
                 695                 700                 705

 Leu Pro Val Ser Gln Arg Ser Gln Asp Leu Ser Leu Gln Glu Ala
                 710                 715                 720

 Glu Thr Glu Gln Ser Asp Thr Leu Asp Asn Lys Glu Ala Val Ile
                 725                 730                 735

 Leu Arg Glu Lys Pro Pro Ser Gly Arg Gln Thr Pro Gln Pro Leu
                 740                 745                 750

 Arg His Gln Ser Tyr Ile Leu Ala Val Asn Asp Gln Glu Thr Gly
                 755                 760                 765

 Ser Asp Thr Thr Cys Trp Leu Pro Asn Asp Ala Arg Arg Glu Val
                 770                 775                 780

 His Ile Lys Arg Met Glu Glu Arg Lys Ala Ser Ser Thr Ser Pro
                 785                 790                 795

 Pro Gly Asp Ser Leu Ala Ser Ile Pro Phe Ile Asp Glu Pro Thr
                 800                 805                 810

 Ser Pro Ser Ile Asp His Asp Ile Ala His Ile Pro Ala Ser Ala
                 815                 820                 825

 Val Ile Ser Ala Ser Thr Ser Gln Val Pro Ser Ile Ala Thr Val
                 830                 835                 840

 Pro Pro Cys Leu Thr Thr Ser Ala Pro Leu Ile Arg Arg Gln Leu
                 845                 850                 855

 Ser His Asp His Glu Ser Val Gly Pro Pro Ser Leu Asp Ala Gln
                 860                 865                 870

 Pro Asn Ser Lys Thr Glu Arg Ser Lys Ser Tyr Asp Glu Gly Leu
                 875                 880                 885

 Asp Asp Tyr Arg Glu Asp Ala Lys Leu Ser Phe Lys His Val Pro
                 890                 895                 900

 Ser Leu Lys Gly Ile Lys Ile Ala Asp Ser Gln Lys Ser Ser Glu
                 905                 910                 915

 Asp Ser Gly Ser Arg Lys Asp Ser Ser Ser Glu Val Phe Ser Asp
                 920                 925                 930

 Ala Ala Lys Glu Gly Trp Leu His Phe Arg Pro Leu Val Thr Asp
                 935                 940                 945

 Lys Gly Lys Arg Val Gly Gly Ser Ile Arg Pro Trp Lys Gln Met
                 950                 955                 960

 Tyr Val Val Leu Arg Gly His Ser Leu Tyr Leu Tyr Lys Asp Lys
                 965                 970                 975

 Arg Glu Gln Thr Thr Pro Ser Glu Glu Glu Gln Pro Ile Ser Val
                 980                 985                 990

 Asn Ala Cys Leu Ile Asp Ile Ser Tyr Ser Glu Thr Lys Arg Lys
                 995                1000                1005

 Asn Val Phe Arg Leu Thr Thr Ser Asp Cys Glu Cys Leu Phe Gln
                1010                1015                1020

 Ala Glu Asp Arg Asp Asp Met Leu Ala Trp Ile Lys Thr Ile Gln
                1025                1030                1035

 Glu Ser Ser Asn Leu Asn Glu Glu Asp Thr Gly Val Thr Asn Arg
                1040                1045                1050

 Asp Leu Ile Ser Arg Arg Ile Lys Glu Tyr Asn Asn Leu Met Ser
                1055                1060                1065

 Lys Ala Glu Gln Leu Pro Lys Thr Pro Arg Gln Ser Leu Ser Ile
                1070                1075                1080

 Arg Gln Thr Leu Leu Gly Ala Lys Ser Glu Pro Lys Thr Gln Ser
                1085                1090                1095

 Pro His Ser Pro Lys Glu Glu Ser Glu Arg Lys Leu Leu Ser Lys
                1100                1105                1110

 Asp Asp Thr Ser Pro Pro Lys Asp Lys Gly Thr Trp Arg Lys Gly
                1115                1120                1125

 Ile Pro Ser Ile Met Arg Lys Thr Phe Glu Lys Lys Pro Thr Ala
                1130                1135                1140

 Thr Gly Thr Phe Gly Val Arg Leu Asp Asp Cys Pro Pro Ala His
                1145                1150                1155

 Thr Asn Arg Tyr Ile Pro Leu Ile Val Asp Ile Cys Cys Lys Leu
                1160                1165                1170

 Val Glu Glu Arg Gly Leu Glu Tyr Thr Gly Ile Tyr Arg Val Pro
                1175                1180                1185

 Gly Asn Asn Ala Ala Ile Ser Ser Met Gln Glu Glu Leu Asn Lys
                1190                1195                1200

 Gly Met Ala Asp Ile Asp Ile Gln Asp Asp Lys Trp Arg Asp Leu
                1205                1210                1215

 Asn Val Ile Ser Ser Leu Leu Lys Ser Phe Phe Arg Lys Leu Pro
                1220                1225                1230

 Glu Pro Leu Phe Thr Asn Asp Lys Tyr Ala Asp Phe Ile Glu Ala
                1235                1240                1245

 Asn Arg Lys Glu Asp Pro Leu Asp Arg Leu Lys Thr Leu Lys Arg
                1250                1255                1260

 Leu Ile His Asp Leu Pro Glu His His Tyr Glu Thr Leu Lys Phe
                1265                1270                1275

 Leu Ser Ala His Leu Lys Thr Val Ala Glu Asn Ser Glu Lys Asn
                1280                1285                1290

 Lys Met Glu Pro Arg Asn Leu Ala Ile Val Phe Gly Pro Thr Leu
                1295                1300                1305

 Val Arg Thr Ser Glu Asp Asn Met Thr His Met Val Thr His Met
                1310                1315                1320

 Pro Asp Gln Tyr Lys Ile Val Glu Thr Leu Ile Gln His His Asp
                1325                1330                1335

 Trp Phe Phe Thr Glu Glu Gly Ala Glu Glu Pro Leu Thr Thr Val
                1340                1345                1350

 Gln Glu Glu Ser Thr Val Asp Ser Gln Pro Val Pro Asn Ile Asp
                1355                1360                1365

 His Leu Leu Thr Asn Ile Gly Arg Thr Gly Val Ser Pro Gly Asp
                1370                1375                1380

 Val Ser Asp Ser Ala Thr Ser Asp Ser Thr Lys Ser Lys Gly Ser
                1385                1390                1395

 Trp Gly Ser Gly Lys Asp Gln Tyr Ser Arg Glu Leu Leu Val Ser
                1400                1405                1410

 Ser Ile Phe Ala Ala Ala Ser Arg Lys Arg Lys Lys Pro Lys Glu
                1415                1420                1425

 Lys Ala Gln Pro Ser Ser Ser Glu Asp Glu Leu Asp Asn Val Phe
                1430                1435                1440

 Phe Lys Lys Glu Asn Val Glu Gln Cys His Asn Asp Thr Lys Glu
                1445                1450                1455

 Glu Ser Lys Lys Glu Ser Glu Thr Leu Gly Arg Lys Gln Lys Ile
                1460                1465                1470

 Ile Ile Ala Lys Glu Asn Ser Thr Arg Lys Asp Pro Ser Thr Thr
                1475                1480                1485

 Lys Asp Glu Lys Ile Ser Leu Gly Lys Glu Ser Thr Pro Ser Glu
                1490                1495                1500

 Glu Pro Ser Pro Pro His Asn Ser Lys His Asn Lys Ser Pro Thr
                1505                1510                1515

 Leu Ser Cys Arg Phe Ala Ile Leu Lys Glu Ser Pro Arg Ser Leu
                1520                1525                1530

 Leu Ala Gln Lys Ser Ser His Leu Glu Glu Thr Gly Ser Asp Ser
                1535                1540                1545

 Gly Thr Leu Leu Ser Thr Ser Ser Gln Ala Ser Leu Ala Arg Phe
                1550                1555                1560

 Ser Met Lys Lys Ser Thr Ser Pro Glu Thr Lys His Ser Glu Phe
                1565                1570                1575

 Leu Ala Asn Val Ser Thr Ile Thr Ser Asp Tyr Ser Thr Thr Ser
                1580                1585                1590

 Ser Ala Thr Tyr Leu Thr Ser Leu Asp Ser Ser Arg Leu Ser Pro
                1595                1600                1605

 Glu Val Gln Ser Val Ala Glu Ser Lys Gly Asp Glu Ala Asp Asp
                1610                1615                1620

 Glu Arg Ser Glu Leu Ile Ser Glu Gly Arg Pro Val Glu Thr Asp
                1625                1630                1635

 Ser Glu Ser Glu Phe Pro Val Phe Pro Thr Ala Leu Thr Ser Glu
                1640                1645                1650

 Arg Leu Phe Arg Gly Lys Leu Gln Glu Val Thr Lys Ser Ser Arg
                1655                1660                1665

 Arg Asn Ser Glu Gly Ser Glu Leu Ser Cys Thr Glu Gly Ser Leu
                1670                1675                1680

 Thr Ser Ser Leu Asp Ser Arg Arg Gln Leu Phe Ser Ser His Lys
                1685                1690                1695

 Leu Ile Glu Cys Asp Thr Leu Ser Arg Lys Lys Ser Ala Arg Phe
                1700                1705                1710

 Lys Ser Asp Ser Gly Ser Leu Gly Asp Ala Lys Asn Glu Lys Glu
                1715                1720                1725

 Ala Pro Ser Leu Thr Lys Val Phe Asp Val Met Lys Lys Gly Lys
                1730                1735                1740

 Ser Thr Gly Ser Leu Leu Thr Pro Thr Arg Gly Glu Ser Glu Lys
                1745                1750                1755

 Gln Glu Pro Thr Trp Lys Thr Lys Ile Ala Asp Arg Leu Lys Leu
                1760                1765                1770

 Arg Pro Arg Ala Pro Ala Asp Asp Met Phe Gly Ala Gly Asn His
                1775                1780                1785

 Lys Val Asn Ala Glu Thr Ala Lys Arg Lys Ser Ile Arg Arg Arg
                1790                1795                1800

 His Thr Leu Gly Gly His Arg Asp Ala Thr Glu Ile Ser Val Leu
                1805                1810                1815

 Asn Phe Trp Lys Val His Glu Gln Ser Gly Glu Arg Glu Ser Glu
                1820                1825                1830

 Leu Ser Ala Val Asn Arg Leu Lys Pro Lys Cys Ser Ala Gln Asp
                1835                1840                1845

 Leu Ser Ile Ser Asp Trp Leu Ala Arg Glu Arg Leu Arg Thr Ser
                1850                1855                1860

 Thr Ser Asp Leu Ser Arg Gly Glu Ile Gly Asp Pro Gln Thr Glu
                1865                1870                1875

 Asn Pro Ser Thr Arg Glu Ile Ala Thr Thr Asp Thr Pro Leu Ser
                1880                1885                1890

 Leu His Cys Asn Thr Gly Ser Ser Ser Ser Thr Leu Ala Ser Thr
                1895                1900                1905

 Asn Arg Pro Leu Leu Ser Ile Pro Pro Gln Ser Pro Asp Gln Ile
                1910                1915                1920

 Asn Gly Glu Ser Phe Gln Asn Val Ser Lys Asn Ala Ser Ser Ala
                1925                1930                1935

 Ala Asn Ala Gln Pro His Lys Leu Ser Glu Thr Pro Gly Thr Lys
                1940                1945                1950

 Ala Glu Phe His Pro Cys Leu
                1955

<210> 4074
<211> 1435
<212> DNA
<213> Homo sapien

<400> 4074
 ggcacgaggc ggcggcggag cgggcggcgg agcggcggca gcagcggtga 50

 gcgcgagccc cggagccccg ggcggccggc ctcccgcgcc cgcgcagccc 100

 cgcgtctgcg tccggccgga gacgccgggc cccgcgccgc gccgcgccat 150

 gtcggtgaac atggacgagc tgcggcacca ggtcatgatc aaccagttcg 200

 tgctggccgc gggctgcgcg gccgaccagg cgaagcagct gctgcaggcg 250

 gcccactggc agttcgagac cgcgctgagc acgttcttcc aagaaaccaa 300

 cattcccaac agccaccacc accaccagat gatgtgcact cccagcaaca 350

 cccctgccac gccgcccaac ttccccgatg cgctggccat gttctccaag 400

 ctccgcgcct ccgagggcct gcagagcagc aacagcccca tgacagccgc 450

 agcctgctcc ccacctgcaa acttcagccc cttctgggcc tcgtccccgc 500

 ccagccacca ggcgccctgg atcccgccct cctcccccac caccttccac 550

 cacctccacc gcccacagcc cacgtggccc ccaggagcac agcagggggg 600

 cgcccagcag aaagccatgg cggccatgga cggccagaga tgagactgga 650

 cgccgccggg cgctgggctg gagctggggg cagcccaggg ttgtggggac 700

 acaggagggc cagggagggg ggagccgggg agggcagggg gtttcccgaa 750

 gatcgcactg gaagatttta taaaagaatt tttgtgggtc ggggggacag 800

 taaacttcct gggccacgtg ggtccttcag gagtttttca ggcaagtttt 850

 tcctctgttt ttaatatata actataatat atatgaatag ataaatataa 900

 ctaatgtgcg tgagaatggg cctggcacac ctggggtgct cgggggtagg 950

 gctgccatgc tgcagagctg atggagtgat gttgtgggca caaggcatct 1000

 gtcagctgcc tcctttaaca gccatgcctt ctggaatctg gaagaggaca 1050

 ccactcctgc agtcaccggg cagccacata gcagctgcag gtcccaggag 1100

 ggcctgaggt caaagctgtg gaaggccctc ttggtatcag ggctctctcc 1150

 ccatggcctc ttccccacct ctgattgctg gttgtggccc catagctcat 1200

 cacccctgtc tcctgctgaa tgtgcagggc tgatgtggca ctgaggagct 1250

 gactttggtc aaaggccagg ctctgcccag caggggactt gactgcccct 1300

 cccgctgcgt gtccaggtcc aaagtggaga gcctgccttt gggtttagtt 1350

 cccgaatcag aatcccatct caccagggcg aaattttaat ttaaaaactt 1400

 aaaaagagac ttttctaaaa aaaaaaaaaa aaaaa 1435

<210> 4075
<211> 164
<212> PRT
<213> Homo sapien

<400> 4075
 Met Ser Val Asn Met Asp Glu Leu Arg His Gln Val Met Ile Asn
   1               5                  10                  15

 Gln Phe Val Leu Ala Ala Gly Cys Ala Ala Asp Gln Ala Lys Gln
                  20                  25                  30

 Leu Leu Gln Ala Ala His Trp Gln Phe Glu Thr Ala Leu Ser Thr
                  35                  40                  45

 Phe Phe Gln Glu Thr Asn Ile Pro Asn Ser His His His His Gln
                  50                  55                  60

 Met Met Cys Thr Pro Ser Asn Thr Pro Ala Thr Pro Pro Asn Phe
                  65                  70                  75

 Pro Asp Ala Leu Ala Met Phe Ser Lys Leu Arg Ala Ser Glu Gly
                  80                  85                  90

 Leu Gln Ser Ser Asn Ser Pro Met Thr Ala Ala Ala Cys Ser Pro
                  95                 100                 105

 Pro Ala Asn Phe Ser Pro Phe Trp Ala Ser Ser Pro Pro Ser His
                 110                 115                 120

 Gln Ala Pro Trp Ile Pro Pro Ser Ser Pro Thr Thr Phe His His
                 125                 130                 135

 Leu His Arg Pro Gln Pro Thr Trp Pro Pro Gly Ala Gln Gln Gly
                 140                 145                 150

 Gly Ala Gln Gln Lys Ala Met Ala Ala Met Asp Gly Gln Arg
                 155                 160

<210> 4076
<211> 5475
<212> DNA
<213> Homo sapien

<400> 4076
 gaaaagagag cacgcaaaac aacatgggat gatccgcaca gagataacag 50

 gagctgagat tgcggaagaa atggagaagg aaaggcgcct ctttcagctc 100

 caaatgtgtg aatatctcat taaagttaat gaaatcaaga ccaaaaaggg 150

 tgtggatctg ctgcagaatc ttataaagta ttaccatgca cagtgcaatt 200

 tctttcaaga tggcttgaaa acagctgata agttgaaaca gtacattgaa 250

 aaactggctg ctgatttata taatataaaa cagacccagg atgaagaaaa 300

 gaaacagcta actgcactcc gagacttaat aaaatcctct cttcaactgg 350

 atcagaaaga atctaggaga gattctcaga gccggcaagg aggatacagc 400

 atgcatcagc tccagggcaa taaggaatat ggcagtgaaa agaaggggta 450

 cctgctaaag aaaagtgacg ggatccggaa agtatggcag aggaggaagt 500

 gttcagtcaa gaatgggatt ctaaccatct cacatgccac atctaacagg 550

 caaccagcca agttgaacct tctcacctgc caagtaaaac ctaatgccga 600

 agacaaaaaa tcttttgacc tgatatcaca taatagaaca tatcactttc 650

 aggcagaaga tgagcaggat tatgtagcat ggatatcagt attgacaaat 700

 agcaaagaag aggccctaac catggccttc cgtggagagc agagtgcggg 750

 agagaacagc ctggaagacc tgacaaaagc cattattgag gatgtccagc 800

 ggctcccagg gaatgacatt tgctgcgatt gtggctcatc agaacccacc 850

 tggctttcaa ccaacttggg tattttgacc tgtatagaat gttctggcat 900

 ccatagggaa atgggggttc atatttctcg cattcagtct ttggaactag 950

 acaaattagg aacttctgaa ctcttgctgg ccaagaatgt aggaaacaat 1000

 agttttaatg atattatgga agcaaattta cccagcccct caccaaaacc 1050

 caccccttca agtgatatga ctgtacgaaa agaatatatc actgcaaagt 1100

 atgtagatca taggttttca aggaagacct gttcaacttc atcagctaaa 1150

 ctaaatgaat tgcttgaggc catcaaatcc agggatttac ttgcactaat 1200

 tcaagtctat gcagaagggg tagagctaat ggaaccactg ctggaacctg 1250

 ggcaggagct tggggagaca gcccttcacc ttgccgtccg aactgcagat 1300

 cagacatctc tccatttggt tgacttcctt gtacaaaact gtgggaacct 1350

 ggataagcag acggccctgg gaaacacagt tctacactac tgtagtatgt 1400

 acagtaaacc tgagtgtttg aagcttttgc tcaggagcaa gcccactgtg 1450

 gatatagtta accaggctgg agaaactgcc ctagacatag caaagagact 1500

 aaaagctacc cagtgtgaag atctgctttc ccaggctaaa tctggaaagt 1550

 tcaatccaca cgtccacgta gaatatgagt ggaatcttcg acaggaggag 1600

 atagatgaga gcgatgatga tctggatgac aaaccaagcc ctatcaagaa 1650

 agagcgctca cccagacctc agagcttctg ccactcctcc agcatctccc 1700

 cccaggacaa gctggcactg ccaggattca gcactccaag ggacaaacag 1750

 cggctctcct atggagcctt caccaaccag atcttcgttt ccacaagcac 1800

 agactcgccc acatcaccaa ccacggaggc tccccctctg cctcctagga 1850

 acgccgggaa aggtccaact ggcccacctt caacactccc tctaagcacc 1900

 cagacctcta gtggcagctc caccctatcc aagaagaggc ctcctccccc 1950

 accacccgga cacaagagaa ccctatccga ccctcccagc ccactacctc 2000

 atgggccccc aaacaaaggc gcagttcctt ggggtaacga tgggggtcca 2050

 tcctcttcaa gtaagactac aaacaagttt gagggactat cccagcagtc 2100

 gagcaccagt tctgcaaaga ctgcccttgg cccaagagtt cttcctaaac 2150

 tacctcagaa agtggcacta aggaaaacag atcatctctc cctagacaaa 2200

 gccaccatcc cgcccgaaat ctttcagaaa tcatcacagt tggcagagtt 2250

 gccacaaaag ccaccacctg gagacctgcc cccaaagccc acagaactgg 2300

 cccccaagcc ccaaattgga gatttgccgc ctaagccagg agaactgccc 2350

 cccaaaccac agctggggga cctgccaccc aaaccccaac tctcagactt 2400

 acctcccaaa ccacagatga aggacctgcc ccccaaacca cagctgggag 2450

 acctgctagc aaaatcccag actggagatg tctcacccaa ggctcagcaa 2500

 ccctctgagg tcacactgaa gtcacaccca ttggatctat ccccaaatgt 2550

 gcagtccaga gacgccatcc aaaagcaagc atctgaagac tccaacgacc 2600

 tcacgcctac tctgccagag acgcccgtac cactgcccag aaaaatcaat 2650

 acggggaaaa ataaagtgag gcgagtgaag accatttatg actgccaggc 2700

 agacaacgat gacgagctca cattcatcga gggagaagtg attatcgtca 2750

 caggggaaga ggaccaggag tggtggattg gccacatcga aggacagcct 2800

 gaaaggaagg gggtctttcc agtgtccttt gttcatatcc tgtctgacta 2850

 gcaaaacgca gaaccttaag attgtccaca tccttcatgc aagactgctg 2900

 ccttcatgta accctgggca cagtgtgtat atagctgctg ttacagagta 2950

 agaaactcat ggaagggcca cctcaggagg gggatataat gtgtgttgta 3000

 aatatcctgt ggttttctgc cttcaccagt atgagggtag cctcggaccc 3050

 ggcgcgcctt actggtttgc caaagccatc cttggcatct agcacttaca 3100

 tctctctatg ctgttctaca agcaaacaaa caaaaatagg agtataggaa 3150

 ctgctggctt tgcaaataga agtggtctcc agcaaccgtt gaaaggcata 3200

 gaattgactc tgttcctaac aatgcagtat tctcaattgt gttactgaaa 3250

 atgcaacatt agcaaagagg tgggttctgt tttccaggtg aaacttttag 3300

 ctccatgaca gaccagcctg tagttatctg tgtacacagt ttacagctac 3350

 aaaaacctac tttggtattt attacagaaa agtgctcagt taaatgtaag 3400

 tgttattcct tcagcaaaat attcactgac ccaaaactct ttatggcatt 3450

 ttacaatgca cacagcctca tgcaagttta gacaagtgga tttatactgt 3500

 cttatgagtg cccgcccctg atatattacc tcattatgca aaaataacat 3550

 atctttcatg actattttga caaaagttta aaacacatat gaagttcaaa 3600

 tttcaggaac caaggactgc cagaaaatat tagcctctac attacgcatg 3650

 catttagaag cttacctgaa atctgccttt tataaaggaa tagtatggat 3700

 aagtggaatt gtacattttt taaacttgat tgccattaaa gcagaaatta 3750

 taaggttgca acaatatttg tttctaatca ctggctttct caagagtatg 3800

 gattgacata ttgtgttatg aatgcacatc tctcagatgt gttgaagcat 3850

 ccattgcatc cattttttat tattttctta gttttgttct tggacaaatt 3900

 taaactttta aaagattatt caagatgaat ttaaaagtca acccttcaca 3950

 cagtttccct actgtatgta gaatccaggt gctgaaacca agtgtttctt 4000

 ttcccatgct ctttgttaaa ccccaattat agataatttt tccagtctta 4050

 agctctgtcc accttcaagt caattcataa ccaagttttt gaacgctgct 4100

 atgaattgca ctgtgaaaag cactcttccc tctcagtttt cttttcatcc 4150

 cagccatgtt tatcagatcc ttaagaacat tgtatttcag tcttttacat 4200

 cagtctgaat tttggaaaag aatgcaatag ttgtactcca cagtcagtgg 4250

 aactgttccc tgagtccgag gctcatgtgt cattctggca ctacatttgc 4300

 ttaaattgct attttggcaa cagcacagaa aactaatatt tttaagcaga 4350

 gaatcttggc aatgagtgag agatgttaat ttcacagaag cacaactccc 4400

 aacccaaccc ttaggaaaag ccctcttcca tcgttacagt gctcagtgaa 4450

 tattaattta gttctgctta agtggttgct atacaaactt tgaatagcca 4500

 cctaataaat aaaccttgca tgacaaacct gcaaaatatt ttatcagctg 4550

 ttattggaaa gtgattttaa gcaattgctt cctcagtgtc agggcacatg 4600

 tgaatttcca caccaaacag agcatgagga accagttgac atgctgggtt 4650

 gtgactggca gctttagcag cctcggtact gaagccacac cagtgtccgg 4700

 atggaagtct gcatctgagg ttgctcagtg tcccggtcat tcatttacac 4750

 attttaactt gcattaaaga gctgttcttt tctgtggcct agactctttt 4800

 cactgatctc aaaataaact ggtttttttc aaaaaaaaaa aaaaaacaaa 4850

 aacaaaaaaa aaacacaaaa gctgcatgtc taaaattaca tggagttagt 4900

 gtctattctt tttccccttt tgcagcaact tacacagcat ttttaacacc 4950

 ttttttttct agtttttttg ttcggttttg ttttccatca ggaatttgag 5000

 ttctctctaa cccagcttac tgtgggacat aggaaaactc agtagaaata 5050

 cctttggtga tcttgttgag tttaagtctg atcttgatct taaactcagt 5100

 aagccactat ctgcaatttt gtacattata tagtattttg aagatatgga 5150

 accttatgaa aaaaaaatag caaattagtt ctttttcccc cagaggggaa 5200

 agttatgttc tgcaaatagt gtgtgtctta ttttactgtt gaacagcaat 5250

 tgctatttat ttttttattg cctagaactt caacatgttg tataggaatc 5300

 ctgtagtgcc actagttaaa tgccgaattc tcatctggat gttaccatca 5350

 aacatcagta cacttgtcat ttcacatgtg tttaatgtga cagtttttca 5400

 gtactgtatg tgttaatttc tacttttttt aatatttaaa attgctttta 5450

 aataaacata ttctcagttg atccc 5475

<210> 4077
<211> 2458
<212> DNA
<213> Homo sapien

<400> 4077
 atgggaaaaa tgcttagagg ttactatttt gactacaaag ttgagttttt 50

 ttctgtagtt accataattt cattgaagca aatgaatgag tttgagaggt 100

 ttgtttttat agttgtgttg tattacttgt ttaataataa tctctaattc 150

 tgtgatcagg tacttttttt gtgggggttt ttttttgttt tttttttttt 200

 gttgttgttt ttgggccatt tctaagccta ccagatctgc tttatgaaat 250

 ccaggggacc aatgcatttt atcactaaaa ctatttttat ataattttaa 300

 gaatatacca aaagttgtct gatttaaagt tgtaatacat gatttctcac 350

 tttcatgtaa ggttatccac ttttgctgaa gatatttttt attgaatcaa 400

 agattgagtt acaattatac ttttcttacc taagtggata aaatgtactt 450

 ttgatgaatc agggaatttt tttaaagttg gagtttagtt ctaaattgac 500

 tttacgtatt actgcagtta attccttttt tggctagggg tggtttgata 550

 aaccacaatt ggctgatatt gaaaatgaaa gaaacttaaa aggtgggatg 600

 gatcatgatt actgtcgata actgcagata aatttgatta gagtaataat 650

 tttgtcattt aaaaacacag ttgtttatac tgcccatcct aggatgctca 700

 ccttccaaga ttcaacgtgg ctaaaacatc ttctggtaaa ttgtgcgtcc 750

 atattcattt tgtcagtagc caggagaaat ggggatgggg gaaatacgac 800

 ttagtgaggc atagacatcc ctggtccatc ctttctgtct ccagctgttt 850

 cttggaacct gctctcctgc ttgctggtcc ctgacgcaga gaccgttgcc 900

 tcccccacag ccgtttgact gaaggctgct ctggagacct agagtaaaac 950

 ggctgatgga agttgtggga cccacttcca tttccttcag tcattagagg 1000

 tggaagggag gggtctccaa gtttggagat tgagcagatg aggcttggga 1050

 tgcccctgct ttgacttcag ccatggatga ggagtgggat ggcagcaagg 1100

 tggctcctgt ggcagtggag ttgtgccaga aacagtggcc agttgtatcg 1150

 cctataagac agggtaaggt ccgaagagct gagcctgtaa ttctgctgta 1200

 ataatgatag tgctcaagaa gtgccttgag ttggtgtaca gtgccatggc 1250

 catcaagaat cccagatttc aggttttatt acaaaatgta agtggtcact 1300

 tggcgatttt gtagtacatg catgagttac cttttttctc tatgtctgag 1350

 aactgtcaga ttataacaag atggcaaaga gatcgttaga gtgcacaaca 1400

 aaatcactat cccattagac acatcatcaa aagcttattt ttattcttgc 1450

 actggaagaa tcgtaagtca actgtttctt gaccatggca gtgttctggc 1500

 tccaaatggt agtgattcca aataatggtt ctgttaacac tttggcagaa 1550

 aatgccagct cagatatttt gagatactaa ggattatctt tggacatgta 1600

 ctgcagcttc ttgtctctgt tttggattac tggaataccc atgggccctc 1650

 tcaagagtgc tggacttcta ggacattaag atgattgtca gtacattaaa 1700

 cttttcaatc ccattatgca atcttgtttg taaatgtaaa cttctaaaaa 1750

 tatggttaat aacattcaac ctgtttatta caacttaaaa ggaacttcag 1800

 tgaatttgtt tttatttttt aacaagattt gtgaactgaa tatcatgaac 1850

 catgttttga tacccctttt tcacgttgtg ccaacggaat agggtgtttg 1900

 atatttcttc atatgttaag gagatgcttc aaaatgtcaa ttgctttaaa 1950

 cttaaattac ctctcaagag accaaggtac atttacctca ttgtgtatat 2000

 aatgtttaat atttgtcaga gcattctcca ggtttgcagt tttatttcta 2050

 taaagtatgg gtattatgtt gctcagttac tcaaatggta ctgtattgtt 2100

 tatatttgta ccccaaataa catcgtctgt actttctgtt ttctgtattg 2150

 tatttgtgca ggattcttta ggctttatca gtgtaatctc tgccttttaa 2200

 gatatgtaca gaaaatgtcc atataaattt ccattgaagt cgaatgatac 2250

 tgagaagcct gtaaaaagga gaaaaaaaca taagctgtgt ttccccataa 2300

 gtttttttaa attgtatatt gtatttgtag taatattcca aaagaatgta 2350

 aataggaaat agaagagtga tgcttatgtt aagtcctaac actatagtag 2400

 aagaatggta gcagtgcaaa taaattacat ttttcccaaa aaaaaaaaaa 2450

 aaaaaaaa 2458

<210> 4078
<211> 47
<212> PRT
<213> Homo sapien

<400> 4078
 Met Gly Ile Met Leu Leu Ser Tyr Ser Asn Gly Thr Val Leu Phe
   1               5                  10                  15

 Ile Phe Val Pro Gln Ile Thr Ser Ser Val Leu Ser Val Phe Cys
                  20                  25                  30

 Ile Val Phe Val Gln Asp Ser Leu Gly Phe Ile Ser Val Ile Ser
                  35                  40                  45

 Ala Phe


<210> 4079
<211> 4415
<212> DNA
<213> Homo sapien

<400> 4079
 gaccgcggct gcaggaacgg aggcggaagg ggccctgcgg cgacgacgtc 50

 gtcgacgggg gtggccgtgg gagctgagca cggagaagac tccctctctc 100

 ggaagccgga tcccgagccg ggcaggatgg atcaccacca gccggggact 150

 gggcgctacc aggtgcttct taatgaagag gataactcag aatcatcggc 200

 tatagagcag ccacctactt caaacccagc accgcagatt gtgcaggctg 250

 tgtcttcagc accagcactt gaaactgact cttcccctcc accatatagt 300

 agtattactg tggaagtacc tacaacttca gatacagaag tttacggtga 350

 gttttatccc gtgccacctc cctatagcgt tgctacctct cttcctacat 400

 acgatgaagc tgagaaggct aaagctgctg caatggcagc tgcagcagca 450

 gaaacatctc aaagaattca ggaggaagag tgtccaccaa gagatgactt 500

 cagtgatgca gaccagctca gagtggggaa tgatggcatt ttcatgctgg 550

 catttttcat ggcatttatt ttcaactggc ttggattttg tttatccttc 600

 tgtatcacca ataccatagc tggaaggtat ggtgctatct gcggatttgg 650

 cctttccttg atcaaatgga tccttattgt caggttttct gattatttta 700

 ctggatattt caatggacag tattggcttt ggtggatatt tcttgtactt 750

 ggcctgctcc ttttcttcag aggatttgtt aattatctaa aagtcagaaa 800

 catgtctgaa agtatggcag ctgctcatag aacaaggtat ttcttcttat 850

 tgtagagact gcatcaaccc gacattcctt tcttatacca atgtgaaatt 900

 tccagatcat ctgtaaacct acaactttaa tagaagacta ctaataacag 950

 aagacaaatt agtgaagaaa agacggagtt tcgaaattga atggcagggt 1000

 ggtttttgct tacaagccat ttctgttcat tctttaagta tctatatttc 1050

 atttgttttg cacatatgca tatgtgccca tttaagatat ttgcatatac 1100

 ttgatagaaa ccataaagtt gtagcagtta agtccagtca catttggtta 1150

 atcagtgttt gatataattg aaagagttga gtggataaac agtcttccag 1200

 cttgtaaatg ccattgactt ctgacctgac atttagtata ataaaaatga 1250

 aattcttaac catgtcaaat gatttagttt ctggctctta gactcatctg 1300

 gcagttctac acatgaaaca tcttttgtta tataaggtgt attgaaacct 1350

 gcagtgctga ttattagaaa ggatttgtcg gatttttgaa catgatattt 1400

 acattattat ttaggaaaac tcttcctgta aataaccatg cataacttac 1450

 tttctgcaat gttttcttag aaattgtgtc cagatagctt tcactaattt 1500

 taaattaagt gaactaaata tatatgtgta tatgtataca catatatata 1550

 cacacacaca tatatatatt tagaaacgtg agtgttaaag atagaatttg 1600

 ttttaggaca aattttaaga aaatgtggga ataccaaatg tcctttataa 1650

 gaaaaataaa ttttgtttta agggacatac cagttttagg gattttcaga 1700

 tgggaagctg catttttagg attgcccatc ttaagagatc ttgcaggaag 1750

 agattgtatt agatattata tttatttcat ttaagataat tttcaaagtt 1800

 aattttctaa ataagataat tctcatttgt gtttgtcttt taaaaggcca 1850

 ataaaatatc tttcagtatc attgtaataa ttttttagag tttaatttgt 1900

 aaagcttagc aaataaaatc ttgtactatg aatagcttct tgctttatga 1950

 ctttaggatt aacttgtaaa aaacatatcc tgaactgaga tatgcaaaat 2000

 actcattttc aagttatgga aatgtgtttg tggcatatag gactgtgggg 2050

 tctgtgtgtg tagtgagagt gtgtagccac tattataact ggaatttaat 2100

 ttacattcat aaactactat atttcccatc ttgcaaatca ttttatgtct 2150

 catctgtttt tcctttcggt tatatctttg gttttgaata ccaacattta 2200

 aaatgatggt attttatctt ttaaacttaa aaattattta atacagctat 2250

 atggacctta taaaattgat ttcttattta ttattagaca ttactactaa 2300

 aaggtacatc taactattca gggacatttt tccatttcca aaaaataaaa 2350

 tttattatgc tttataacct cttctgtatt ttctaatttt ttcattgtct 2400

 ttgataaata aaacagtttt gttttgctaa tatagcctat tttttgtttt 2450

 gtctcattca gtttactttc ctgcgtagaa tttttattgt tatattaaaa 2500

 tttttattgt tgtattaaag tacctgtgtt acaccccttg aagtaagaca 2550

 gtagcatggg gtaaagaaaa aatatttagt ttagttgcct aatttggaag 2600

 ttaattaaaa ttaaactgta ctaataacat attcaaactc atgctggatc 2650

 tctttcatat taatttctta tagacctgta ctttattctt tcaataattt 2700

 ttaaatgaaa ttaagctttg ctacatggta attaaataat tactaggaag 2750

 cttagctatc aaacatcgac ttactaaaat ttcattttag cttttatggt 2800

 atatgtgctt gttttctgaa tatggataca tgttactttt gatccagcat 2850

 caaaacttca ctttttgttt tgacttttcc ccccaaatct gtaaggttca 2900

 agtatacata ttactgaatc ctctataatt ggcataattc aatggtagcc 2950

 ttaaatctca tcatgtaagc aggggaatca gaatgttatt ttcaagaact 3000

 taatgttccc ttcagatata taaaatcctg catacttcat ttcctgtgag 3050

 cttgaacagc tgctgttgtg ttttggggat gcttgatcat ctttgcactc 3100

 tgccttaaag attgaaaaat caaaactctt gttagggtat ctaaacattt 3150

 ttgagtgtga actggggatt ggaagttaat acaaaaaaat ttcaaattat 3200

 ttctattgta aatgaataag ctagtcatgg ctaggataat ccattttcat 3250

 gtatttatgc aataaactga attttaaggc aaaaacaaca cttttctata 3300

 tagtgtatgc aggacagatt ttagaaactt agattaaaat acaaatccca 3350

 ttacatttgg ttaaaatgaa tctctgctta atggaaaaaa tactaatctt 3400

 tagcctattt tgagtctata agatatattt cattttagac atgccttcta 3450

 agttgttcac agatttttac ctgctaaaac aatattattt ccagtaaaac 3500

 ctctcctaac aggaaaagtg gagttcaaaa tatccaattg gagaaaaatt 3550

 cagagttcct tcattaaata taattttttt catctagtat gtactatttc 3600

 aagaagtgca aaaagtaatg atagtgaatg tgataccata cttaactaag 3650

 gtaatatata tccttagttt gctcaaaaga gtcctggtta ttcctgtttt 3700

 ctcagcttaa tagtgcctca tcgtactctc aaaagtgttc taatttggag 3750

 gataagttat atgatcatcc tgtgtataat tgtagactgt accaagaagc 3800

 aactacctta gctccactgc cctttgaggg atggaactgg ggtaagggca 3850

 ggagccagtt attattgcca cagtgttttc taatgaacca tttggcctgt 3900

 agaagaggaa tagtattttt tttaatagtt gtatttgaat gattccagct 3950

 tatcgtaaat actaaactga atggctttta tatttttaac tgctgttaaa 4000

 tgttatttta gcatttatta gttgtttatt atttaattct tcaaatagtc 4050

 atatgaaaac atatatttga taaaggtcaa ttgttagatg ataatgtgcc 4100

 attcattatc ataggaatgt ccttgcccat atataaaaca tgctggcatg 4150

 tattttactt gttaataaag ttgtatagat gtggaagtgt gaacctgtga 4200

 tgcatccttt tcaaaatcag tttaagattc gcatattatc atgactgtga 4250

 cctcactaaa ctgtttatgt gacaaacctt tcaagattgg agatgaaaac 4300

 aacacttgtg aaattaggtt ggggttgcaa catcttttaa cttctcagtt 4350

 atttgtatgt caggaaacag attgtggttt aattttaata aacaaaatat 4400

 catctttttg aaaat 4415

<210> 4080
<211> 284
<212> PRT
<213> Homo sapien

<400> 4080
 Asp Arg Gly Cys Arg Asn Gly Gly Gly Arg Gly Pro Ala Ala Thr
   1               5                  10                  15

 Thr Ser Ser Thr Gly Val Ala Val Gly Ala Glu His Gly Glu Asp
                  20                  25                  30

 Ser Leu Ser Arg Lys Pro Asp Pro Glu Pro Gly Arg Met Asp His
                  35                  40                  45

 His Gln Pro Gly Thr Gly Arg Tyr Gln Val Leu Leu Asn Glu Glu
                  50                  55                  60

 Asp Asn Ser Glu Ser Ser Ala Ile Glu Gln Pro Pro Thr Ser Asn
                  65                  70                  75

 Pro Ala Pro Gln Ile Val Gln Ala Val Ser Ser Ala Pro Ala Leu
                  80                  85                  90

 Glu Thr Asp Ser Ser Pro Pro Pro Tyr Ser Ser Ile Thr Val Glu
                  95                 100                 105

 Val Pro Thr Thr Ser Asp Thr Glu Val Tyr Gly Glu Phe Tyr Pro
                 110                 115                 120

 Val Pro Pro Pro Tyr Ser Val Ala Thr Ser Leu Pro Thr Tyr Asp
                 125                 130                 135

 Glu Ala Glu Lys Ala Lys Ala Ala Ala Met Ala Ala Ala Ala Ala
                 140                 145                 150

 Glu Thr Ser Gln Arg Ile Gln Glu Glu Glu Cys Pro Pro Arg Asp
                 155                 160                 165

 Asp Phe Ser Asp Ala Asp Gln Leu Arg Val Gly Asn Asp Gly Ile
                 170                 175                 180

 Phe Met Leu Ala Phe Phe Met Ala Phe Ile Phe Asn Trp Leu Gly
                 185                 190                 195

 Phe Cys Leu Ser Phe Cys Ile Thr Asn Thr Ile Ala Gly Arg Tyr
                 200                 205                 210

 Gly Ala Ile Cys Gly Phe Gly Leu Ser Leu Ile Lys Trp Ile Leu
                 215                 220                 225

 Ile Val Arg Phe Ser Asp Tyr Phe Thr Gly Tyr Phe Asn Gly Gln
                 230                 235                 240

 Tyr Trp Leu Trp Trp Ile Phe Leu Val Leu Gly Leu Leu Leu Phe
                 245                 250                 255

 Phe Arg Gly Phe Val Asn Tyr Leu Lys Val Arg Asn Met Ser Glu
                 260                 265                 270

 Ser Met Ala Ala Ala His Arg Thr Arg Tyr Phe Phe Leu Leu
                 275                 280

<210> 4081
<211> 4585
<212> DNA
<213> Homo sapien

<400> 4081
 gaggaggccg cagcagtcgc cgcgcgaaca tggcggccga aatccactcc 50

 aggccgcaga gcagccgccc ggtgctgctg agcaagatcg aggggcacca 100

 ggacgccgtc acggccgcgc tgctcatccc caaggaggac ggcgtgatca 150

 cggccagcga ggacagaacc atccgggtat ggctgaaaag agacagtggt 200

 caatactggc ccagcattta ccacacaatg gcctctcctt gctctgctat 250

 ggcttaccat catgacagca gacggatatt tgtgggccag gataatggag 300

 ctgtaatgga atttcacgtt tctgaagatt ttaataaaat gaactttatc 350

 aagacctacc cagctcatca gaaccgggtg tctgcgatta tcttcagctt 400

 ggccacagag tgggtgatca gtaccggcca cgacaagtgt gtgagctgga 450

 tgtgcacgcg gagcgggaac atgctcggga ggcacttctt cacgtcctgg 500

 gcttcgtgtc tgcaatatga ctttgacact cagtatgctt tcgttggtga 550

 ttattctggg cagatcaccc tgctgaagct tgaacagaac acgtgttcag 600

 tcatcacaac cctcaaagga catgaaggta gtgtcgcctg cctctggtgg 650

 gaccctattc agcggttact cttctcagga gcatctgaca acagcatcat 700

 catgtgggac atcggaggaa ggaaaggccg gacgctgtta cttcagggcc 750

 atcatgacaa ggtgcagtcg ctgtgctacc ttcagctcac caggcagctc 800

 gtctcctgtt cctcggacgg cggaattgca gtgtggaaca tggatgttag 850

 cagagaagag gctcctcagt ggttggaaag tgattcttgt cagaaatgtg 900

 agcagccatt tttctggaac ataaagcaga tgtgggacac caagacgctg 950

 gggctaagac aacatcactg caggaaatgc gggcaggctg tctgcgggaa 1000

 gtgcagcagc aagcgctcaa gttacccagt catgggcttc gagttccaag 1050

 tccgggtttg tgattcttgt tacgactcca tcaaagatga agatcggact 1100

 tctctagcga cctttcatga aggaaaacat aacatttccc acatgtccat 1150

 ggacattgcc aggggactga tggtgacctg tgggaccgac cgcattgtaa 1200

 agatctggga catgacacct gtggtgggct gcagtctggc gactgggttt 1250

 tctccgcact gatctgagag ctgggcggcg tccacaccta agaacagcag 1300

 ctccaccaaa tgaagtccct ctcacgcagc tccacagcgc tgtctcgtga 1350

 atggacagta gccacttaca aacaaatcaa cattcttaaa aagaaaatgt 1400

 aaaggtgtgt tttggggcat ttgtggaact tacccatggg gactaatatg 1450

 gaaaaggtct gtccatagtg gttccctgaa gactggaatt acttcagcaa 1500

 aacttcccca tgaacagcta atgtgtagtg aaagaatgag ctagcaaatg 1550

 agttttagcg gggacaaaaa atcaaacaaa aaagtgaatg cttagaacct 1600

 tctcaaagca gtcacaagta cagacacttc acttagccta gggggccttc 1650

 cagggttctt gtggctgttg tcagagcagg agctggggga gggaagactt 1700

 gttctctctt tcttgagggg tggcattagg aacttacgaa accagagacc 1750

 tttccctatg acttggcagt atgtgaatat cctctacact tagttattga 1800

 taaacttctt aaagagatct gttattttca ggtagtgcca taatctgcac 1850

 ttagcattgg cttgcttcag ttgtttctct tcccagccag tatgccacag 1900

 gtgaactttc gaggttgtca ttaagtaagt tgtgaaattt ctgtaataac 1950

 aaaggcagtc cgcattcttc cctttccccc aaattcctag ggcaaaactt 2000

 ttttatggtg ctgttaacat gggagtcaca caagccgcct gactttttct 2050

 cattgccatt agtaatgact gatggaaaac ccagccacca ctgtgatgcg 2100

 aaatgatcag tctgttgcct gaaacagccc agtcctctta actgaaacag 2150

 cattctactt cttgttccaa gatgagcctc tgcaatattc tggcaattta 2200

 atataccccc tacaaaagca ctccacagct tttacactat tttgactttg 2250

 agttataact agtattattc atgttttcat aaaaagaagt tagtgaccca 2300

 gagctataat catccatcaa gtcttccaca ataattccca actcataaat 2350

 tgctttccta acaactagca aaagctattg ttcataatgg catttaaagc 2400

 ttttgggcac tgtgtaccag gatgaggaag agaagaaatg aggagcctgt 2450

 cttttaatat tccagtattt gtgtgtttga ttttttttga caacagtaca 2500

 tatatctatt tctctaggga tatggaagta agtggagaag ggcctacctt 2550

 tttaaaggac aaatataaaa atagcaacag tatctttgct aatcttacta 2600

 atggatattg attaaaaaaa aaaaacctca gtactgcatc actgtgttgg 2650

 gatcgtacca ggacaatagg gtcattccat atgataaaac taaaggacta 2700

 aatttgtttt ataatgatgt cttagaggga ctgaaaagtt taaggaggcg 2750

 atcgaactaa aatgtcttaa tggctgtgtg acacacgtaa ggaaaggaaa 2800

 gggggtcacg cacatcatgt actggaatga tctgcattaa acattgactt 2850

 gtcttcagaa ataagactga agggttttgt tgttccttag agttttcgtg 2900

 ttacatcacc taaagagatt tcttttaaaa actttctaga ctctttgcaa 2950

 aatgtatatt actaacatag tttggaagaa aaattgagta gtggtaagtt 3000

 ttgttcaagc acaatgttga atgttaagct tcctgtatta attttagttc 3050

 agttaatggt tcagcccata caaaggtgct atcctaggga ttttatgaat 3100

 tcctgaaagg aaaatagaat atgatcaatt ccttgccctg tggaagagtg 3150

 cagaactgtg gttttgtttt cctttgactt ctgtaaaatg tgaccgtttg 3200

 acatctgtgg tagattgaac ggaatatcac agctgctgag tttactccat 3250

 agctttcaaa ccttttttat tttaagaaat tcttgaaaaa ccctatgttc 3300

 catgggaaca taaagttatt atagtgcctc ctaaggggtt aatataaatc 3350

 aaggaggaag tttatattta aggaagaatt ggagtgacgt atcttagaaa 3400

 aggaaaggct gatgtttcca tatagcttgc tctccaccag gcctatcatt 3450

 tttcttttta gagacaaacg tgacaggcta gtcttgtctc tctcatatgc 3500

 taggtagcaa atggggtgat atttttatag aagtgggcaa aaattatttt 3550

 ctcaatttta ctgagtaggc acagaagaaa agtacagata ggctgatggt 3600

 tattgcctta ttttgactgc atttctctta aatggatcat ttaaattagt 3650

 tcttcaagta acagtttact ggttgttcca ttcctgaata tgcaggctaa 3700

 tttgtacaga tagggattaa ggaatacaga ctattagaga agatccttat 3750

 atttacatct agtatatatg tggtaaggaa atgccgattc ttcattataa 3800

 acaagtttta aaattgttct ttcttagttc aaatgatagc aataccccta 3850

 tagcattagg tagaaacaaa ttattcatta catcgtaaat ctctttacta 3900

 tgtcctagct ctgtcctgct acctaaagga tataaagaaa tattattgct 3950

 ctagaatgta ttactttgtt ctcccatgaa agaattcagt ttgttagtac 4000

 ctatattttt aaactggtga aactgaccca aatatgtaat aaataccata 4050

 gtagctcaga cccaaggaga tatttttcta aaatcagttt tcgttaaagt 4100

 acttctactt ccgttattgg atatggtatc tcctaaagtg taaaaaaaat 4150

 ctgttactat atagtgataa accatctgct catcgtaagt gtaaggctta 4200

 acaaataagt aatacatgct atatttattc aagtgtctat tgcttaattg 4250

 ttaattgtga gcagatttat tgaatgccta ttctattttc tgcagtttac 4300

 aatacaataa ctctttgagt aagttgaagt ttaattgtgc aacaaatttg 4350

 tattagagta caatttaaag tgtttttctc tatagccttt tttgactggg 4400

 gaagcaaggg gtaatgttaa ttagtacact ttgttcttgt actagctatg 4450

 tttctataag atatggtgcc ctgtgtatcc cagagatgct agaaaactgt 4500

 tctttgctcc tatttgtggg ttctgttttt gtgggttttt tttttttttg 4550

 agaaaatgta cacaataaaa cattccttgc ttgtt 4585

<210> 4082
<211> 410
<212> PRT
<213> Homo sapien

<400> 4082
 Met Ala Ala Glu Ile His Ser Arg Pro Gln Ser Ser Arg Pro Val
   1               5                  10                  15

 Leu Leu Ser Lys Ile Glu Gly His Gln Asp Ala Val Thr Ala Ala
                  20                  25                  30

 Leu Leu Ile Pro Lys Glu Asp Gly Val Ile Thr Ala Ser Glu Asp
                  35                  40                  45

 Arg Thr Ile Arg Val Trp Leu Lys Arg Asp Ser Gly Gln Tyr Trp
                  50                  55                  60

 Pro Ser Ile Tyr His Thr Met Ala Ser Pro Cys Ser Ala Met Ala
                  65                  70                  75

 Tyr His His Asp Ser Arg Arg Ile Phe Val Gly Gln Asp Asn Gly
                  80                  85                  90

 Ala Val Met Glu Phe His Val Ser Glu Asp Phe Asn Lys Met Asn
                  95                 100                 105

 Phe Ile Lys Thr Tyr Pro Ala His Gln Asn Arg Val Ser Ala Ile
                 110                 115                 120

 Ile Phe Ser Leu Ala Thr Glu Trp Val Ile Ser Thr Gly His Asp
                 125                 130                 135

 Lys Cys Val Ser Trp Met Cys Thr Arg Ser Gly Asn Met Leu Gly
                 140                 145                 150

 Arg His Phe Phe Thr Ser Trp Ala Ser Cys Leu Gln Tyr Asp Phe
                 155                 160                 165

 Asp Thr Gln Tyr Ala Phe Val Gly Asp Tyr Ser Gly Gln Ile Thr
                 170                 175                 180

 Leu Leu Lys Leu Glu Gln Asn Thr Cys Ser Val Ile Thr Thr Leu
                 185                 190                 195

 Lys Gly His Glu Gly Ser Val Ala Cys Leu Trp Trp Asp Pro Ile
                 200                 205                 210

 Gln Arg Leu Leu Phe Ser Gly Ala Ser Asp Asn Ser Ile Ile Met
                 215                 220                 225

 Trp Asp Ile Gly Gly Arg Lys Gly Arg Thr Leu Leu Leu Gln Gly
                 230                 235                 240

 His His Asp Lys Val Gln Ser Leu Cys Tyr Leu Gln Leu Thr Arg
                 245                 250                 255

 Gln Leu Val Ser Cys Ser Ser Asp Gly Gly Ile Ala Val Trp Asn
                 260                 265                 270

 Met Asp Val Ser Arg Glu Glu Ala Pro Gln Trp Leu Glu Ser Asp
                 275                 280                 285

 Ser Cys Gln Lys Cys Glu Gln Pro Phe Phe Trp Asn Ile Lys Gln
                 290                 295                 300

 Met Trp Asp Thr Lys Thr Leu Gly Leu Arg Gln His His Cys Arg
                 305                 310                 315

 Lys Cys Gly Gln Ala Val Cys Gly Lys Cys Ser Ser Lys Arg Ser
                 320                 325                 330

 Ser Tyr Pro Val Met Gly Phe Glu Phe Gln Val Arg Val Cys Asp
                 335                 340                 345

 Ser Cys Tyr Asp Ser Ile Lys Asp Glu Asp Arg Thr Ser Leu Ala
                 350                 355                 360

 Thr Phe His Glu Gly Lys His Asn Ile Ser His Met Ser Met Asp
                 365                 370                 375

 Ile Ala Arg Gly Leu Met Val Thr Cys Gly Thr Asp Arg Ile Val
                 380                 385                 390

 Lys Ile Trp Asp Met Thr Pro Val Val Gly Cys Ser Leu Ala Thr
                 395                 400                 405

 Gly Phe Ser Pro His
                 410

<210> 4083
<211> 4415
<212> DNA
<213> Homo sapien

<400> 4083
 gaccgcggct gcaggaacgg aggcggaagg ggccctgcgg cgacgacgtc 50

 gtcgacgggg gtggccgtgg gagctgagca cggagaagac tccctctctc 100

 ggaagccgga tcccgagccg ggcaggatgg atcaccacca gccggggact 150

 gggcgctacc aggtgcttct taatgaagag gataactcag aatcatcggc 200

 tatagagcag ccacctactt caaacccagc accgcagatt gtgcaggctg 250

 tgtcttcagc accagcactt gaaactgact cttcccctcc accatatagt 300

 agtattactg tggaagtacc tacaacttca gatacagaag tttacggtga 350

 gttttatccc gtgccacctc cctatagcgt tgctacctct cttcctacat 400

 acgatgaagc tgagaaggct aaagctgctg caatggcagc tgcagcagca 450

 gaaacatctc aaagaattca ggaggaagag tgtccaccaa gagatgactt 500

 cagtgatgca gaccagctca gagtggggaa tgatggcatt ttcatgctgg 550

 catttttcat ggcatttatt ttcaactggc ttggattttg tttatccttc 600

 tgtatcacca ataccatagc tggaaggtat ggtgctatct gcggatttgg 650

 cctttccttg atcaaatgga tccttattgt caggttttct gattatttta 700

 ctggatattt caatggacag tattggcttt ggtggatatt tcttgtactt 750

 ggcctgctcc ttttcttcag aggatttgtt aattatctaa aagtcagaaa 800

 catgtctgaa agtatggcag ctgctcatag aacaaggtat ttcttcttat 850

 tgtagagact gcatcaaccc gacattcctt tcttatacca atgtgaaatt 900

 tccagatcat ctgtaaacct acaactttaa tagaagacta ctaataacag 950

 aagacaaatt agtgaagaaa agacggagtt tcgaaattga atggcagggt 1000

 ggtttttgct tacaagccat ttctgttcat tctttaagta tctatatttc 1050

 atttgttttg cacatatgca tatgtgccca tttaagatat ttgcatatac 1100

 ttgatagaaa ccataaagtt gtagcagtta agtccagtca catttggtta 1150

 atcagtgttt gatataattg aaagagttga gtggataaac agtcttccag 1200

 cttgtaaatg ccattgactt ctgacctgac atttagtata ataaaaatga 1250

 aattcttaac catgtcaaat gatttagttt ctggctctta gactcatctg 1300

 gcagttctac acatgaaaca tcttttgtta tataaggtgt attgaaacct 1350

 gcagtgctga ttattagaaa ggatttgtcg gatttttgaa catgatattt 1400

 acattattat ttaggaaaac tcttcctgta aataaccatg cataacttac 1450

 tttctgcaat gttttcttag aaattgtgtc cagatagctt tcactaattt 1500

 taaattaagt gaactaaata tatatgtgta tatgtataca catatatata 1550

 cacacacaca tatatatatt tagaaacgtg agtgttaaag atagaatttg 1600

 ttttaggaca aattttaaga aaatgtggga ataccaaatg tcctttataa 1650

 gaaaaataaa ttttgtttta agggacatac cagttttagg gattttcaga 1700

 tgggaagctg catttttagg attgcccatc ttaagagatc ttgcaggaag 1750

 agattgtatt agatattata tttatttcat ttaagataat tttcaaagtt 1800

 aattttctaa ataagataat tctcatttgt gtttgtcttt taaaaggcca 1850

 ataaaatatc tttcagtatc attgtaataa ttttttagag tttaatttgt 1900

 aaagcttagc aaataaaatc ttgtactatg aatagcttct tgctttatga 1950

 ctttaggatt aacttgtaaa aaacatatcc tgaactgaga tatgcaaaat 2000

 actcattttc aagttatgga aatgtgtttg tggcatatag gactgtgggg 2050

 tctgtgtgtg tagtgagagt gtgtagccac tattataact ggaatttaat 2100

 ttacattcat aaactactat atttcccatc ttgcaaatca ttttatgtct 2150

 catctgtttt tcctttcggt tatatctttg gttttgaata ccaacattta 2200

 aaatgatggt attttatctt ttaaacttaa aaattattta atacagctat 2250

 atggacctta taaaattgat ttcttattta ttattagaca ttactactaa 2300

 aaggtacatc taactattca gggacatttt tccatttcca aaaaataaaa 2350

 tttattatgc tttataacct cttctgtatt ttctaatttt ttcattgtct 2400

 ttgataaata aaacagtttt gttttgctaa tatagcctat tttttgtttt 2450

 gtctcattca gtttactttc ctgcgtagaa tttttattgt tatattaaaa 2500

 tttttattgt tgtattaaag tacctgtgtt acaccccttg aagtaagaca 2550

 gtagcatggg gtaaagaaaa aatatttagt ttagttgcct aatttggaag 2600

 ttaattaaaa ttaaactgta ctaataacat attcaaactc atgctggatc 2650

 tctttcatat taatttctta tagacctgta ctttattctt tcaataattt 2700

 ttaaatgaaa ttaagctttg ctacatggta attaaataat tactaggaag 2750

 cttagctatc aaacatcgac ttactaaaat ttcattttag cttttatggt 2800

 atatgtgctt gttttctgaa tatggataca tgttactttt gatccagcat 2850

 caaaacttca ctttttgttt tgacttttcc ccccaaatct gtaaggttca 2900

 agtatacata ttactgaatc ctctataatt ggcataattc aatggtagcc 2950

 ttaaatctca tcatgtaagc aggggaatca gaatgttatt ttcaagaact 3000

 taatgttccc ttcagatata taaaatcctg catacttcat ttcctgtgag 3050

 cttgaacagc tgctgttgtg ttttggggat gcttgatcat ctttgcactc 3100

 tgccttaaag attgaaaaat caaaactctt gttagggtat ctaaacattt 3150

 ttgagtgtga actggggatt ggaagttaat acaaaaaaat ttcaaattat 3200

 ttctattgta aatgaataag ctagtcatgg ctaggataat ccattttcat 3250

 gtatttatgc aataaactga attttaaggc aaaaacaaca cttttctata 3300

 tagtgtatgc aggacagatt ttagaaactt agattaaaat acaaatccca 3350

 ttacatttgg ttaaaatgaa tctctgctta atggaaaaaa tactaatctt 3400

 tagcctattt tgagtctata agatatattt cattttagac atgccttcta 3450

 agttgttcac agatttttac ctgctaaaac aatattattt ccagtaaaac 3500

 ctctcctaac aggaaaagtg gagttcaaaa tatccaattg gagaaaaatt 3550

 cagagttcct tcattaaata taattttttt catctagtat gtactatttc 3600

 aagaagtgca aaaagtaatg atagtgaatg tgataccata cttaactaag 3650

 gtaatatata tccttagttt gctcaaaaga gtcctggtta ttcctgtttt 3700

 ctcagcttaa tagtgcctca tcgtactctc aaaagtgttc taatttggag 3750

 gataagttat atgatcatcc tgtgtataat tgtagactgt accaagaagc 3800

 aactacctta gctccactgc cctttgaggg atggaactgg ggtaagggca 3850

 ggagccagtt attattgcca cagtgttttc taatgaacca tttggcctgt 3900

 agaagaggaa tagtattttt tttaatagtt gtatttgaat gattccagct 3950

 tatcgtaaat actaaactga atggctttta tatttttaac tgctgttaaa 4000

 tgttatttta gcatttatta gttgtttatt atttaattct tcaaatagtc 4050

 atatgaaaac atatatttga taaaggtcaa ttgttagatg ataatgtgcc 4100

 attcattatc ataggaatgt ccttgcccat atataaaaca tgctggcatg 4150

 tattttactt gttaataaag ttgtatagat gtggaagtgt gaacctgtga 4200

 tgcatccttt tcaaaatcag tttaagattc gcatattatc atgactgtga 4250

 cctcactaaa ctgtttatgt gacaaacctt tcaagattgg agatgaaaac 4300

 aacacttgtg aaattaggtt ggggttgcaa catcttttaa cttctcagtt 4350

 atttgtatgt caggaaacag attgtggttt aattttaata aacaaaatat 4400

 catctttttg aaaat 4415

<210> 4084
<211> 2457
<212> DNA
<213> Homo sapien

<400> 4084
 acaggaagtg aagagcttcc gccgggagac cgcggctgca ggaacggagg 50

 cggaaggggc cctgcggcga cgacgtcgtc gacgggggtg gccgtgggag 100

 ctgagcacgg agaagactcc ctctctcgga agccggatcc cgagccgggc 150

 aggatggatc accaccagcc ggggactggg cgctaccagg tgcttcttaa 200

 tgaagaggat aactcagaat catcggctat agagcagcca cctacttcaa 250

 acccagcacc gcagattgtg caggctgcgt cttcagcacc agcacttgaa 300

 actgactctt cccctccacc atatagtagt attactgtgg aagtacctac 350

 aacttcagat acagaagttt acggtgagtt ttatcccgtg ccacctccct 400

 atagcgttgc tacctctctt cctacatacg atgaagctga gaaggctaaa 450

 gctgctgcaa tggcagctgc agcagcagaa acatctcaaa gaattcagga 500

 ggaagagtgt ccaccaagag atgacttcag tgatgcagac cagctcagag 550

 tggggaatga tggcattttc atgctggcat ttttcatggc atttattttc 600

 aactggcttg gattttgttt atccttctgt atcaccaata ccatagctgg 650

 aaggtatggt gctatctgcg gatttggcct ttccttgatc aaatggatcc 700

 ttattgtcag gttttctgat tattttactg gatatttcaa tggacagtat 750

 tggctttggt ggatatttct tgtacttggc ctgctccttt tcttcagagg 800

 atttgttaat tatctaaaag tcagaaacat gtctgaaagt atggcagctg 850

 ctcatagaac aaggtatttc ttcttattgt agagactgca tcaacccgac 900

 attcctttct tataccaatg tgaaatttcc agatcatctg taaacctaca 950

 actttaatag aagactacta ataacagaag acaaattagt gaagaaaaga 1000

 cggagtttcg aaattgaatg gcagggtggt ttttgcttac aagccatttc 1050

 tgttcattct ttaagtatct atatttcatt tgttttgcac atatgcatat 1100

 gtgcccattt aagatatttg catatacttg atagaaacca taaagttgta 1150

 gcagttaagt ccagtcacat ttggttaatc agtgtttgat ataattgaaa 1200

 gagttgagtg gataaacagt cttccagctt gtaaatgcca ttgacttctg 1250

 acctgacatt tagtataata aaaatgaaat tcttaaccat gtcaaatgat 1300

 ttagtttctg gctcttagac tcatctggca gttctacaca tgaaacatct 1350

 tttgttatat aaggtgtatt gaaacctgca gtgctgatta ttagaaagga 1400

 tttgtcagat ttttgaacat gatatttaca ttattattta ggaaaactct 1450

 tcctgtaaat aaccatgcat aacttacttt ctgcaatgtt ttcttagaaa 1500

 ttgtgtccag atagctttca ctaattttaa attaagtgaa ctaaatatat 1550

 atgtgtatat gtatactcat atatatacac acacacacat atatatatct 1600

 agaaacgtga gtgttaaaga tagaatttgt tttaggacaa attttaagaa 1650

 aatgtgggaa taccaaatgt cctttataag aaaaataaat tttattttaa 1700

 gggacatact agttttaggg attttcagat gggaagctgc atttttagga 1750

 ttgcccatct taagagatct tgcaggaaga gattgtatta gatattatat 1800

 ttatttcatt taagataatt ttcaaagtta attttctaaa taagataatt 1850

 ctcatttgtg tttgtctttt aaaaggccaa taaaatatct ttcagtatca 1900

 ttgtaataat tttttagagt ttaatttgta aagcttagca aataaaatct 1950

 tgtactatga atagcttctt gctttatgac tttaggatta acttgtaaaa 2000

 aacatatcct gaactgagat atgcaaaata ctcattttca agttatggaa 2050

 atgtgtttgt ggcatatagg actgtggggt ctgtgtgtgt agtgagagtg 2100

 tgtagccact attataactg gaatttaatt tacattcata aactactata 2150

 tttcccatct tgcaaatcat tttatgtctc atctgttttt cctttcggtt 2200

 atatctttgg ttttgaatac caacatttaa aatgatggta ttttatcttt 2250

 taaacttaaa aattatttaa tacagctata tggaccttat aaaattgatt 2300

 tcttatttat tattagacat tactactaaa aggtacatct aactattcag 2350

 ggacattttt ccatttccaa aaaataaaat ttattatgct ttataacctc 2400

 ttctgtattt tctaattttt tcattgtctt tgataaataa aacagttttg 2450

 ttttgct 2457

<210> 4085
<211> 242
<212> PRT
<213> Homo sapien

<400> 4085
 Met Asp His His Gln Pro Gly Thr Gly Arg Tyr Gln Val Leu Leu
   1               5                  10                  15

 Asn Glu Glu Asp Asn Ser Glu Ser Ser Ala Ile Glu Gln Pro Pro
                  20                  25                  30

 Thr Ser Asn Pro Ala Pro Gln Ile Val Gln Ala Ala Ser Ser Ala
                  35                  40                  45

 Pro Ala Leu Glu Thr Asp Ser Ser Pro Pro Pro Tyr Ser Ser Ile
                  50                  55                  60

 Thr Val Glu Val Pro Thr Thr Ser Asp Thr Glu Val Tyr Gly Glu
                  65                  70                  75

 Phe Tyr Pro Val Pro Pro Pro Tyr Ser Val Ala Thr Ser Leu Pro
                  80                  85                  90

 Thr Tyr Asp Glu Ala Glu Lys Ala Lys Ala Ala Ala Met Ala Ala
                  95                 100                 105

 Ala Ala Ala Glu Thr Ser Gln Arg Ile Gln Glu Glu Glu Cys Pro
                 110                 115                 120

 Pro Arg Asp Asp Phe Ser Asp Ala Asp Gln Leu Arg Val Gly Asn
                 125                 130                 135

 Asp Gly Ile Phe Met Leu Ala Phe Phe Met Ala Phe Ile Phe Asn
                 140                 145                 150

 Trp Leu Gly Phe Cys Leu Ser Phe Cys Ile Thr Asn Thr Ile Ala
                 155                 160                 165

 Gly Arg Tyr Gly Ala Ile Cys Gly Phe Gly Leu Ser Leu Ile Lys
                 170                 175                 180

 Trp Ile Leu Ile Val Arg Phe Ser Asp Tyr Phe Thr Gly Tyr Phe
                 185                 190                 195

 Asn Gly Gln Tyr Trp Leu Trp Trp Ile Phe Leu Val Leu Gly Leu
                 200                 205                 210

 Leu Leu Phe Phe Arg Gly Phe Val Asn Tyr Leu Lys Val Arg Asn
                 215                 220                 225

 Met Ser Glu Ser Met Ala Ala Ala His Arg Thr Arg Tyr Phe Phe
                 230                 235                 240

 Leu Leu


<210> 4086
<211> 1290
<212> DNA
<213> Homo sapien

<400> 4086
 ccacgcgtcc ggactagttc taggtcgcga tctagaaccc cacgcgtccg 50

 gaagtcctta tagtccaggg cctgtttccc tgtagcagct ccttattgct 100

 ggagaaggag aaaagtgccc aagatccttt caggatattt ggttttttgg 150

 gcgcgacaca aatcgaggtg agggaagaga gaggaaaatc ccctgaatcc 200

 ctgcaggatt aatttattca aaaaggaaat aaaaaatact caatatgcaa 250

 aagtcttgtg aagaaaatga gggaaaacca cagaacatgc caaaggccga 300

 ggaagatcgc cctttggagg atgtaccaca ggaggcagaa ggaaatcctc 350

 aaccttccga agaaggcgta agccaggaag cagaaggaaa ccccagagga 400

 gggccgaatc agcctggcca gggatttaaa gaggacacac ccgttaggca 450

 tttggaccct gaagaaatga taagaggagt agatgagctt gaaaggctta 500

 gggaagagat aagaagagta agaaacaagt ttgtgatgat gcattggaag 550

 caaagacatt cacgcagccg tccttatcct gtgtgcttta ggccttgaat 600

 tcatttttgc ctaatattaa aatctggccc cagctttctt tctgttagca 650

 ttttctgatg tatctttgac ctccatttta cttttaatca tctgatgaaa 700

 ttttgtttta ggtaatttcc ttggtaccag catctcattg gattttggat 750

 tttgacccat tttccaggtc tatttttcaa ttggaaactt tcacacattt 800

 gcatgggaat atgttcattc catgttgtaa agtaaaacat aacaggttat 850

 ggcaaagcag catatttaat atcagctcac atatgtagga taaaattcca 900

 aactttgtgt gtgtgcgtgt gtgtatacat acatccatat aacatatatc 950

 acaaacttaa ccaagcttat ttctgtgtgg tgtgaaattt tatttgtttt 1000

 cttctttttg ttctttttgc ttatatgtac tttttaatga acacgtgtct 1050

 cacacacaaa aagaattaag gatttttttt acaagtaaga gtcaaataat 1100

 ttgcaaccag cttatgaggg caatgggggc acctaaactc ttgatgaaag 1150

 aactttaaaa agaaatgtaa acctcaaatt acctctggat ctcttagcca 1200

 gaggaataaa ctggcaatta ttacagaaaa aaaaaaaaaa aaaaaaaaaa 1250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1290

<210> 4087
<211> 117
<212> PRT
<213> Homo sapien

<400> 4087
 Met Gln Lys Ser Cys Glu Glu Asn Glu Gly Lys Pro Gln Asn Met
   1               5                  10                  15

 Pro Lys Ala Glu Glu Asp Arg Pro Leu Glu Asp Val Pro Gln Glu
                  20                  25                  30

 Ala Glu Gly Asn Pro Gln Pro Ser Glu Glu Gly Val Ser Gln Glu
                  35                  40                  45

 Ala Glu Gly Asn Pro Arg Gly Gly Pro Asn Gln Pro Gly Gln Gly
                  50                  55                  60

 Phe Lys Glu Asp Thr Pro Val Arg His Leu Asp Pro Glu Glu Met
                  65                  70                  75

 Ile Arg Gly Val Asp Glu Leu Glu Arg Leu Arg Glu Glu Ile Arg
                  80                  85                  90

 Arg Val Arg Asn Lys Phe Val Met Met His Trp Lys Gln Arg His
                  95                 100                 105

 Ser Arg Ser Arg Pro Tyr Pro Val Cys Phe Arg Pro
                 110                 115

<210> 4088
<211> 4790
<212> DNA
<213> Homo sapien

<400> 4088
 gaaagagaca ttcacttgga gggctcttgc tgaaaatggg tttaactctc 50

 cttttgccag tcaccaccag cctgacctca tacactttta gtacaatgga 100

 gtggctgagc ctttgagcac accaccatta catcatcgtg gcaaattaaa 150

 gaaggaggtg ggaaaagagg acttattgtt gtcatggccc atgagatgat 200

 tggaactcaa attgttactg agaggttggt ggctctgctg gaaagtggaa 250

 cggaaaaagt gctgctaatt gatagccggc catttgtgga atacaataca 300

 tcccacattt tggaagccat taatatcaac tgctccaagc ttatgaagcg 350

 aaggttgcaa caggacaaag tgttaattac agagctcatc cagcattcag 400

 cgaaacataa ggttgacatt gattgcagtc agaaggttgt agtttacgat 450

 caaagctccc aagatgttgc ctctctctct tcagactgtt ttctcactgt 500

 acttctgggt aaactggaga agagcttcaa ctctgttcac ctgcttgcag 550

 gtgggtttgc tgagttctct cgttgtttcc ctggcctctg tgaaggaaaa 600

 tccactctag tccctacctg catttctcag ccttgcttac ctgttgccaa 650

 cattgggcca acccgaattc ttcccaatct ttatcttggc tgccagcgag 700

 atgtcctcaa caaggagctg atgcagcaga atgggattgg ttatgtgtta 750

 aatgccagca atacctgtcc aaagcctgac tttatccccg agtctcattt 800

 cctgcgtgtg cctgtgaatg acagcttttg tgagaaaatt ttgccgtggt 850

 tggacaaatc agtagatttc attgagaaag caaaagcctc caatggatgt 900

 gttctagtgc actgtttagc tgggatctcc cgctccgcca ccatcgctat 950

 cgcctacatc atgaagagga tggacatgtc tttagatgaa gcttacagat 1000

 ttgtgaaaga aaaaagacct actatatctc caaacttcaa ttttctgggc 1050

 caactcctgg actatgagaa gaagattaag aaccagactg gagcatcagg 1100

 gccaaagagc aaactcaagc tgctgcacct ggagaagcca aatgaacctg 1150

 tccctgctgt ctcagagggt ggacagaaaa gcgagacgcc cctcagtcca 1200

 ccctgtgccg actctgctac ctcagaggca gcaggacaaa ggcccgtgca 1250

 tcccgccagc gtgcccagcg tgcccagcgt gcagccgtcg ctgttagagg 1300

 acagcccgct ggtacaggcg ctcagtgggc tgcacctgtc cgcagacagg 1350

 ctggaagaca gcaataagct caagcgttcc ttctctctgg atatcaaatc 1400

 agtttcatat tcagccagca tggcagcatc cttacatggc ttctcctcat 1450

 cagaagatgc tttggaatac tacaaacctt ccactactct ggatgggacc 1500

 aacaagctat gccagttctc ccctgttcag gaactatcgg agcagactcc 1550

 cgaaaccagt cctgataagg aggaagccag catccccaag aagctgcaga 1600

 ccgccaggcc ttcagacagc cagagcaagc gattgcattc ggtcagaacc 1650

 agcagcagtg gcaccgccca gaggtccctt ttatctccac tgcatcgaag 1700

 tgggagcgtg gaggacaatt accacaccag cttccttttc ggcctttcca 1750

 ccagccagca gcacctcacg aagtctgctg gcctgggcct taagggctgg 1800

 cactcggata tcttggcccc ccagacctct accccttccc tgaccagcag 1850

 ctggtatttt gccacagagt cctcacactt ctactctgcc tcagccatct 1900

 acggaggcag tgccagttac tctgcctaca gctgcagcca gctgcccact 1950

 tgcggagacc aagtctattc tgtgcgcagg cggcagaagc caagtgacag 2000

 agctgactcg cggcggagct ggcatgaaga gagccccttt gaaaagcagt 2050

 ttaaacgcag aagctgccaa atggaatttg gagagagcat catgtcagag 2100

 aacaggtcac gggaagagct ggggaaagtg ggcagtcagt ctagcttttc 2150

 gggcagcatg gaaatcattg aggtctcctg agaagaaaga cacttgtgac 2200

 ttctatagac aatttttttt tcttgttcac aaaaaaattc cctgtaaatc 2250

 tgaaatatat atatgtacat acatatatat ttttggaaaa tggagctatg 2300

 gtgtaaaagc aacaggtgga tcaacccagt tgttactctc ttaacatctg 2350

 catttgagag atcagctaat acttctctca acaaaaatgg aagggcagat 2400

 gctaggatcc cccctagacg gaggaaaacc attttattca gtgaattaca 2450

 catcctcttg ttcttaaaaa agcaagtgtc tttggtgttg gaggacaaaa 2500

 tcccctacca ttttcacgtt gtgctactaa gagatctcaa atattagtct 2550

 ttgtccggac ccttccatag tacaccttag cgctgagact gagccagctt 2600

 gggggtcagg taggtagacc ctgttaggga cagagcctag tggtaaatcc 2650

 aagagaaatg atcctatcca aagctgattc acaaacccac gctcacctga 2700

 cagccgaggg acacgagcat cactctgctg gacggaccat taggggcctt 2750

 gccaaggtct accttagagc aaacccagta cctcagacag gaaagtcggg 2800

 gctttgacca ctaccatatc tggtagccca ttttctaggc attgtgaata 2850

 ggtaggtagc tagtcacact tttcagacca attcaaactg tctatgcaca 2900

 aaattcccgt gggcctagat ggagataatt tttttttctt ctcagcttta 2950

 tgaagagaag ggaaactgtc taggattcag ctgaaccacc aggaacctgg 3000

 caacatcacg atttaagcta aggttgggag gctaacgagt ctacctccct 3050

 ctttgtaaat caaagaattg tttaaaatgg gattgtcaat cctttaaata 3100

 aagatgaact tggtttcaag ccaaatgtga atttatttgg gttggtagca 3150

 gagcagcagc accttcaaat tctcagccaa agcagatgtt tttgcccttt 3200

 ctgcttcact gcatggatac agttggtaaa atgtaataat atggcagaat 3250

 tttataggaa acttcctagg gaggtaaatt atgggaagat taagaaaggt 3300

 acaaattgct gaggagaagc aggaaacctg tttccttagt ggcttttatc 3350

 ccctcggcat gcgatggggc tgatgtttct ataattgcct cagactttca 3400

 catttactag tagggctgag agaggcttta gtgaggaagg aatattcaga 3450

 ataaaacggt tgagaaagct gagaagacca ttgagttttg atcagttgtg 3500

 aatagagtgc aaagccatgg ccaagctgtt tttggaaacg ctggccggcg 3550

 tgtcttcagt ggaaaaagca aatcaaaatg gagcgagagc aaaggggcgt 3600

 cctcagtcct caacctacaa tcactgtatg gaatcggtcc tggcagctga 3650

 acataggagg tcactggaac aagtgatagt gcagattggc tttcaaacat 3700

 cctcctggct tgagttttat cagctacagt gtgggtcctc ttttgaagcc 3750

 ttaattcaca acagcagctt tttgggggtg gggctgggcg ggtgttgtca 3800

 ttgttctttc ccttcctgta agtgtcgcta gttgctgcct cgtatctcag 3850

 gtttttctct gtttttgaga aatggacagt tttttgacca ggatgtgact 3900

 tcatgtttcc tatggtgact tctaaaacca gcacagaatg atatgactca 3950

 acacagaccg acttggttat ggggatgatg agccgcacag acctcactag 4000

 ttgtgcacaa ataatgtgct atgatggggt gtaaagtgaa ggcagaagag 4050

 ggtcagccgc attgttatga tactgggaaa gtgctggtca acgatttgag 4100

 ttagttttta gatatacatt gaaatcttta atcagacatt ctcaagtttc 4150

 acacagtagt ttttgatgtt atgtacacac acaccaaatg tgtaacagtt 4200

 caccacttcc agagtgtggt catgcccaaa acatgtttaa gaaaggaaag 4250

 cagtagctcc ttgctaacga tgtttcagga ggtttggggg acttggtttt 4300

 aatgagcttc tgtcatttag ggcttctctt ggccatggtc cccttccttc 4350

 tggaactgtg atgtagtcac atcctacagc ctttagtgct ggttcactag 4400

 tgtcagataa tcagttcttg gaatcgagac tgccgtggcg aaggggtggc 4450

 ctcggaggca ggctctggag ctgcttggat gtctttaggt ggggtggtgg 4500

 ctggctctct tcagcatgta attggggaaa ccctcgtttc tactaggggt 4550

 gatacagatg gtgattttaa agagcaaaac tagacttcta tgtgagaagt 4600

 gctggaaaat gatttaggac atgtgtaaag ttagatggaa agactgtaaa 4650

 tgtttaatat gaatatagtg ttcttttgaa gtaaggccag ctgttgaacg 4700

 gttaaactgt gcatttctca ttttgatgtg tcatgtatgt taatgtatga 4750

 aatgattaaa taaaatcaaa actggtacct gtttatacat 4790

<210> 4089
<211> 690
<212> PRT
<213> Homo sapien

<400> 4089
 Ala Phe Glu His Thr Thr Ile Thr Ser Ser Trp Gln Ile Lys Glu
   1               5                  10                  15

 Gly Gly Gly Lys Arg Gly Leu Ile Val Val Met Ala His Glu Met
                  20                  25                  30

 Ile Gly Thr Gln Ile Val Thr Glu Arg Leu Val Ala Leu Leu Glu
                  35                  40                  45

 Ser Gly Thr Glu Lys Val Leu Leu Ile Asp Ser Arg Pro Phe Val
                  50                  55                  60

 Glu Tyr Asn Thr Ser His Ile Leu Glu Ala Ile Asn Ile Asn Cys
                  65                  70                  75

 Ser Lys Leu Met Lys Arg Arg Leu Gln Gln Asp Lys Val Leu Ile
                  80                  85                  90

 Thr Glu Leu Ile Gln His Ser Ala Lys His Lys Val Asp Ile Asp
                  95                 100                 105

 Cys Ser Gln Lys Val Val Val Tyr Asp Gln Ser Ser Gln Asp Val
                 110                 115                 120

 Ala Ser Leu Ser Ser Asp Cys Phe Leu Thr Val Leu Leu Gly Lys
                 125                 130                 135

 Leu Glu Lys Ser Phe Asn Ser Val His Leu Leu Ala Gly Gly Phe
                 140                 145                 150

 Ala Glu Phe Ser Arg Cys Phe Pro Gly Leu Cys Glu Gly Lys Ser
                 155                 160                 165

 Thr Leu Val Pro Thr Cys Ile Ser Gln Pro Cys Leu Pro Val Ala
                 170                 175                 180

 Asn Ile Gly Pro Thr Arg Ile Leu Pro Asn Leu Tyr Leu Gly Cys
                 185                 190                 195

 Gln Arg Asp Val Leu Asn Lys Glu Leu Met Gln Gln Asn Gly Ile
                 200                 205                 210

 Gly Tyr Val Leu Asn Ala Ser Asn Thr Cys Pro Lys Pro Asp Phe
                 215                 220                 225

 Ile Pro Glu Ser His Phe Leu Arg Val Pro Val Asn Asp Ser Phe
                 230                 235                 240

 Cys Glu Lys Ile Leu Pro Trp Leu Asp Lys Ser Val Asp Phe Ile
                 245                 250                 255

 Glu Lys Ala Lys Ala Ser Asn Gly Cys Val Leu Val His Cys Leu
                 260                 265                 270

 Ala Gly Ile Ser Arg Ser Ala Thr Ile Ala Ile Ala Tyr Ile Met
                 275                 280                 285

 Lys Arg Met Asp Met Ser Leu Asp Glu Ala Tyr Arg Phe Val Lys
                 290                 295                 300

 Glu Lys Arg Pro Thr Ile Ser Pro Asn Phe Asn Phe Leu Gly Gln
                 305                 310                 315

 Leu Leu Asp Tyr Glu Lys Lys Ile Lys Asn Gln Thr Gly Ala Ser
                 320                 325                 330

 Gly Pro Lys Ser Lys Leu Lys Leu Leu His Leu Glu Lys Pro Asn
                 335                 340                 345

 Glu Pro Val Pro Ala Val Ser Glu Gly Gly Gln Lys Ser Glu Thr
                 350                 355                 360

 Pro Leu Ser Pro Pro Cys Ala Asp Ser Ala Thr Ser Glu Ala Ala
                 365                 370                 375

 Gly Gln Arg Pro Val His Pro Ala Ser Val Pro Ser Val Pro Ser
                 380                 385                 390

 Val Gln Pro Ser Leu Leu Glu Asp Ser Pro Leu Val Gln Ala Leu
                 395                 400                 405

 Ser Gly Leu His Leu Ser Ala Asp Arg Leu Glu Asp Ser Asn Lys
                 410                 415                 420

 Leu Lys Arg Ser Phe Ser Leu Asp Ile Lys Ser Val Ser Tyr Ser
                 425                 430                 435

 Ala Ser Met Ala Ala Ser Leu His Gly Phe Ser Ser Ser Glu Asp
                 440                 445                 450

 Ala Leu Glu Tyr Tyr Lys Pro Ser Thr Thr Leu Asp Gly Thr Asn
                 455                 460                 465

 Lys Leu Cys Gln Phe Ser Pro Val Gln Glu Leu Ser Glu Gln Thr
                 470                 475                 480

 Pro Glu Thr Ser Pro Asp Lys Glu Glu Ala Ser Ile Pro Lys Lys
                 485                 490                 495

 Leu Gln Thr Ala Arg Pro Ser Asp Ser Gln Ser Lys Arg Leu His
                 500                 505                 510

 Ser Val Arg Thr Ser Ser Ser Gly Thr Ala Gln Arg Ser Leu Leu
                 515                 520                 525

 Ser Pro Leu His Arg Ser Gly Ser Val Glu Asp Asn Tyr His Thr
                 530                 535                 540

 Ser Phe Leu Phe Gly Leu Ser Thr Ser Gln Gln His Leu Thr Lys
                 545                 550                 555

 Ser Ala Gly Leu Gly Leu Lys Gly Trp His Ser Asp Ile Leu Ala
                 560                 565                 570

 Pro Gln Thr Ser Thr Pro Ser Leu Thr Ser Ser Trp Tyr Phe Ala
                 575                 580                 585

 Thr Glu Ser Ser His Phe Tyr Ser Ala Ser Ala Ile Tyr Gly Gly
                 590                 595                 600

 Ser Ala Ser Tyr Ser Ala Tyr Ser Cys Ser Gln Leu Pro Thr Cys
                 605                 610                 615

 Gly Asp Gln Val Tyr Ser Val Arg Arg Arg Gln Lys Pro Ser Asp
                 620                 625                 630

 Arg Ala Asp Ser Arg Arg Ser Trp His Glu Glu Ser Pro Phe Glu
                 635                 640                 645

 Lys Gln Phe Lys Arg Arg Ser Cys Gln Met Glu Phe Gly Glu Ser
                 650                 655                 660

 Ile Met Ser Glu Asn Arg Ser Arg Glu Glu Leu Gly Lys Val Gly
                 665                 670                 675

 Ser Gln Ser Ser Phe Ser Gly Ser Met Glu Ile Ile Glu Val Ser
                 680                 685                 690

<210> 4090
<211> 5925
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 89-112, 517-541, 2887-2915, 4943-4971
<223> Unknown base

<400> 4090
 gcttccagtt gggatgggga aggcctttgt gtgtgtattg gggggagggg 50

 ttaaaaaata attatcccaa actttttaat gtactgccnn nnnnnnnnnn 100

 nnnnnnnnnn nnccactata ccattttaag ttctgacctc aggcctccat 150

 ttgggccgat ggcctcttgg aggcttaaag ttttctgtac cttgtgatga 200

 atgttaatag gtgtttttat tatacaaagc tgaatgtcat ttctcgtttg 250

 tagctttctg tcactcattc catcttcctt cagacatcac cacgtttctc 300

 taaagtcaga aaacattccg ttttggtctt tttcaaaaag gtcccaaatg 350

 ctgcactcta cacatgaagg ccctctcaca cagacgtgac gtcctgccag 400

 aaagagaatg aatgacagaa aaaaaaaaga gagacaaact ctaggaacaa 450

 tgccgattca ttccacgcag cagtattggg ggtggttcgg gggaggggtg 500

 tttcggattt tcttttnnnn nnnnnnnnnn nnnnnnnnnn nggcagcaac 550

 cattaataaa tgccaccaca ttctaccagc acaaggaaac ataggcagca 600

 ctgaaaaaaa aaaaaaagct catattaatt agactgacaa tatggccttg 650

 gaaggctctc ccttgtggaa ccaagttgcc atgggccttg ggtgctctgc 700

 gataacgggt gtgggttggt tttgtttgca aaatggccaa aaaaaaaaac 750

 cggcttcccc gagcagctgc cctgaaagta ggggtggcgg cggcggcgct 800

 gagtttatac attagttcag acctacttgg tggcattaaa ctgtttgaat 850

 gcaaattcga tttcagattg aacttgttaa gggagttaac gagggctgag 900

 ttcagcaaat gctaaagtgt taatttcaaa tatgcaaatt tggtactgca 950

 gtttgttatg caatattata tcaccaaccc agtatcacaa aaactcatag 1000

 aagatatcat gtaggccctg ggctttgggg gggtcccaaa catggtatgc 1050

 agaaatgtga tggttacagg tcagtacaac ctcagtcctt agaacccctc 1100

 cacacttcag ctctgcaccc actttcctgt catttattta tataggactg 1150

 tagttttttt tagttcgaga gcctttcgaa gcttaattta tattctttct 1200

 ttgtaccttt tttctaaaat taccaaagat attacacaaa ggtaaattat 1250

 gttctctgtt ttatgcttta tctgatgaag ccaaatatcc tcttattgtt 1300

 gatcaaagga ggcaaaagaa tttagaggca aatgacaagc gataggctat 1350

 tgcaacctga gaaagagaac tgctccttca tcgtaaattt agaagaccaa 1400

 gtagataatg gaaccaaagt tgttactttt ttctagtagt tatttttcct 1450

 ttttcttttt gtgtacctct acagagacca aaactcattc tcttaaagag 1500

 attttatggg gctactgcag ataaaaatag gacacaatat taaaggagct 1550

 acagaaggaa gggagtccca tctcaaaaaa aaaatgaatg tatgccactg 1600

 caattagagt atccaataaa ggagacagtt tagagtcagg acagaaaagc 1650

 ttccataatt gaactagatt acataatagt atttctagaa aaagagatat 1700

 ttttagattg tatgccactt ttgtttaaga actgtgctgt gatcactgta 1750

 ttaattttgg tttatcttgg catatatcct tcagtttgtt tttattttta 1800

 atttttcctt tttttccgat taggctttgg tcagcatttt tcatttaaag 1850

 aaaagtaaca ctcccatcca ctcataagct tggtacaaaa acttctctgg 1900

 cagttacttt tgaagcttca ctctgctttc tgtataaagg gcagtctgtg 1950

 gtcacgcaag actttaaaaa aaaaaaaaca aagagcccat aaaaacagac 2000

 aaaaaacttt tccaggcagc ttcatgatgt gcaggcagta gccagacagg 2050

 gtcatgggaa gggggccctg tgcttctaaa ctgagtggtt gctggttagt 2100

 ttggtattca aaagaggata aaaatctggt agattagttc attctcagca 2150

 tgtgtagcta gacatgagta aagataacag catgagaaac tgttagtacg 2200

 catacctcag ttcaaacctt tagggaatga ttaaaattta aaaaaaaaac 2250

 atttcactca gttgcactta gtcgtatgtc ttgcatgctt agtctaaaga 2300

 ctgtagcaaa aaaaaaaaaa aaagaaaaat tagattttac atatctttgc 2350

 aggtatcaca gccttgcaga agaaccaact gaaaaaaaaa ttctcaggct 2400

 ttacagcaag caaacttcac tatgattttt acaattctga ttctgtatcc 2450

 cctgggggtt atcccagttg cttctttagg atggggttta ttacgttgta 2500

 catatatccc gatgtgtctg tgtgaatctt tgtctttttt gggggagggc 2550

 agagggcggt tcttttttta gatattgttc ctaaaaagga ataaatgcat 2600

 acacctgttt gtcaaaacac ctttgctttt tgtgcaactg ctttatatta 2650

 acgatactaa aaaaaaatag ctttggaaaa aaaactactg tatgtaacgg 2700

 aattgcagaa tatgctgcac atgtatttta tttagttatc cttgctttaa 2750

 gaatattgga tgacatttcc tgacatgtgg gagggagaaa ctccctaact 2800

 ttttttttct gcttttaaac tgtaacatag ttgaagattt cttttttctg 2850

 ttctcattga ttggagcatt ttgtacaagt tttgtannnn nnnnnnnnnn 2900

 nnnnnnnnnn nnnnncgtgt gtgttaatct gttttttgat acattcctat 2950

 cccttgtgtt tatcctacca ctgccttcct ggctatctta aacaagttca 3000

 tacatttgaa aagaaaaaaa aatgttgttt aaaaaatgtt ttctcctgct 3050

 gcagtaaata ttttgcatga tgaaattcca gggtcacact tttccaagtt 3100

 tatcagtgaa gtagtgatta acaatgggga gtgtcaaaac tattgaactt 3150

 ttgtataaca caaaaaaaac tttacaaggt gccaagatgt aaagaaaatc 3200

 tgttactttt tttttctcaa agaaaagcat acattaggga ggtagtcccg 3250

 tgtgtcagac aaatgcactg tcaggaatga ggatccaacc tacctgtccc 3300

 tagagtccgt cttgtaagat gagttaggct gccccttgga ccagccacaa 3350

 aatggaatat caaggcttat gtacatacgt gaagagttac caccagtcct 3400

 gccacctttg gacagctcta acaccatccc cagcatccag tcagacctag 3450

 taaagaaaac cttggattct taacccaaga taggctgtaa atcactagct 3500

 tttttttcct catgaaaaaa aatagagtta aaaaatattt cctctctttt 3550

 ccatattcca gctgaactcc gtttccaaag gcacaaagaa gagtgtgctt 3600

 attcagattt tgaatctttt tggtaccttt tggttaatga catagcctcc 3650

 tgaaattctg gatgtcttca aagtcagttt tgcttcttta tcctgaaaat 3700

 cagatttaca atgctgaagg catttcttgg gcccagtgta gctcacgcaa 3750

 tctctgctac ccataagcct tgatgaagat gatacagtcc ggactgtgag 3800

 catggtgctt catgtatatg tgctgccagt aacaagaatt tttttgtttt 3850

 gttttgtttt gttttgataa ggcataaaag aaactcattc cttgacatca 3900

 actgtaattc catcattcca tgtctgcgga tacagacaat aaaaaaaatg 3950

 ttgtgtagtc agtactaatt actgacatta taagcattct caaatgcaat 4000

 aaaaatgctg gttgttcacg ctggtagtaa aagttgccac agcctaagtt 4050

 tgtttccctt tctgacctgc tgatattgta tgttaggcat atgccttagg 4100

 tttatcacca gctgcttcca atgcagaatt aaaatcaatc ttaaagcttt 4150

 catgatcagg gaaggctgaa gctcttatcc tcaggatttc caagtgaaag 4200

 tatccactta gagaattggg aagtaaaaaa aaaagagcaa gagatgttat 4250

 cttttctctt gaggaagcac actcttattt ttttcatcaa attttataaa 4300

 gaaaaacaaa atgtttaata actagcatta agagcaaact aaaatttcag 4350

 aggaaagcaa ctttcatgaa taattcattg aaagatttca cagtctggca 4400

 agattaggtc atccaaataa aagtgctaat ggtcaaaaac atgcaccgtc 4450

 tataatattc tcatcaagaa atctttttgc atataatgat aaatgcttag 4500

 attagaacaa atgattttat aaaaatattc tatcaaaagt atgctagata 4550

 attgcattca ttgaagaaaa cagaacttca gtacctaaat attccagaaa 4600

 aaccatctta attttgagat tttaaaaaaa taattagatg catttaggaa 4650

 atgtgctgtt tctttttaat attactctat agtatatatt ctagggatta 4700

 atgaatttga gcatcacctt tcaataaaaa attaaattgc caatatgaaa 4750

 gcagtatttt aagtggccaa accgtggtaa cataaaacca ttacatatat 4800

 aattcagagc acataattca gggcaaagga tgacttgaaa attaacctcc 4850

 cagtctttat tctgcaaaac acccaccgat gctgaggata caagtgaaca 4900

 ttctttccca gcattgtttt gaaaagccca tattagcaaa gtnnnnnnnn 4950

 nnnnnnnnnn nnnnnnnnnn naacaagtag attttgctat taagttgcaa 5000

 actagtgtcc tctttgaatt aacaattatg ccctatctag aaacccctta 5050

 gtctcaataa ttagcaaaac atttgaacct ttaattctca cctggctact 5100

 gagactataa tcttagggtt aattcaaatt cctgtaatta ccaggcttaa 5150

 acctaaatac tgcttacagc ctatccatta gtaaccattt aaaaatgtac 5200

 agatacttct tttaatcaac tggaggacct aaaccaagta tgacgatatg 5250

 ttagtgaaga ttttgctggt tgaggcatag tacattttaa cttatatttc 5300

 aggaattgtt ctcaagcagg aacactcttt tacatattta tttcaggctt 5350

 gtcactctca taaacgaggc agcaaaccca aaatattggc tcttcttata 5400

 aataggcgcc tttatataaa gaacataaaa ctcttaagac taatttcaca 5450

 ccaacacagg cagcttcata atagtaacca cctctccctc cccactaaaa 5500

 aagataaaaa caaagtataa ttagtctttc ttattagatt tttgtctttg 5550

 atgatattac gtatttatgt gtagggtagt aatcacaatt tatccttcat 5600

 cttcattgta gttgaatcaa ataaaagtat tctttattca aataatgtga 5650

 agttgggtgt ctcaaacctt catttaatga attgatgaaa ggtttaagac 5700

 aaaattcacg ttggagggaa attaagttac atacaaaaac actggtttta 5750

 actgtgggac aatatttgga ttagaaaacc atctctagat ataacctact 5800

 tatatttatt tttaaatggt attttatttt ttaaaataac aaaacccaat 5850

 gttgtcttat ttccactttg attgtaaaat gacattcaat gcttaatacc 5900

 aaaatatata tctatattca cattt 5925

<210> 4091
<211> 64
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 30-37
<223> unknown amino acid

<220>
<221> Unsure
<222> 89-112, 517-541, 2887-2915, 4943-4971
<223> Unknown amino acid

<400> 4091
 Phe Gln Leu Gly Trp Gly Arg Pro Leu Cys Val Tyr Trp Gly Glu
   1               5                  10                  15

 Gly Leu Lys Asn Asn Tyr Pro Lys Leu Phe Asn Val Leu Pro Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa His Tyr Thr Ile Leu Ser Ser Asp
                  35                  40                  45

 Leu Arg Pro Pro Phe Gly Pro Met Ala Ser Trp Arg Leu Lys Val
                  50                  55                  60

 Phe Cys Thr Leu


<210> 4092
<211> 4954
<212> DNA
<213> Homo sapien

<400> 4092
 atcacagctt ggtgctgggg ctcagcatgg ccaggtggct aaccagggct 50

 tggtgtcaac tacatttggg atgatgacac ttggaggaca cagagccact 100

 gtgcagcagg agtcgccact gctaacagcc agagtgtccc agaagctttt 150

 gttgacaatt ccagtttccg aacaaaacat ttcggcaatg gtgagggctt 200

 cgatcccttc tctgatttgc tgtcagccat gaacggatgg atgtgatgcc 250

 tgctagccaa aaggcttccc tctgtgtgtt gcagtcctgt ggcattatgc 300

 atgccccctc ccagtgaccc caggcttttt atggctgtga gacacgttaa 350

 aatttcaggg gtaagacgtg accttttgag gtgactataa ctgaagattg 400

 ctttacagaa gccaaaaaag gtttttgagt catgatgcaa gaatctggga 450

 ctgagacaaa aagtaacggt tcagccatcc agaatgggtc gggcggcagc 500

 aaccacttac tagagtgcgg cggtcttcgg gaggggcggt ccaacggaga 550

 gacgccggcc gtggacatcg gggcagctga cctcgcccac gcccagcagc 600

 agcagcaaca ggcacttcag gtggcaagac agctccttct tcagcagcaa 650

 cagcagcagc aagttagtgg attaaaatct cccaagagga atgacaaaca 700

 accagctctt caggttcccg tgtcagtggc tatgatgaca cctcaagtta 750

 tcactcccca gcaaatgcag cagatcctcc agcaacaagt gctgagccct 800

 cagcagctcc aggttctcct ccagcagcag caggccctca tgcttcaaca 850

 gcagcagctt caagagtttt ataaaaaaca acaggaacag ttgcagcttc 900

 aacttttaca acaacaacat gctggaaaac agcctaaaga gcaacagcag 950

 gtggctaccc agcagttggc ttttcagcag cagcttttac agatgcagca 1000

 gttacagcag cagcacctcc tgtctttgca gcgccaaggc cttctgacaa 1050

 ttcagcccgg gcagcctgcc cttccccttc aacctcttgc tcaaggcatg 1100

 attccaacag aactgcagca gctctggaaa gaagtgacaa gtgctcatac 1150

 tgcagaagaa accacaggca acaatcacag cagtttggat ctgaccacga 1200

 catgtgtctc ctcctctgca ccttccaaga cctccttaat aatgaaccca 1250

 catgcctcta ccaatggaca gctctcagtc cacactccca aaagggaaag 1300

 tttgtcccat gaggagcacc cccatagcca tcctctctat ggacatggtg 1350

 tatgcaagtg gccaggctgt gaagcagtgt gcgaagattt ccaatcattt 1400

 ctaaaacatc tcaacagtga gcatgcgctg gacgatagaa gtacagccca 1450

 atgtagagta caaatgcagg ttgtacagca gttagagcta cagcttgcaa 1500

 aagacaaaga acgcctgcaa gccatgatga cccacctgca tgtgaagtct 1550

 acagaaccca aagccgcccc tcagcccttg aatctagtat caagtgtcac 1600

 tctctccaag tccgcatcgg aggcttctcc acagagctta cctcatactc 1650

 caacgacccc aaccgccccc ctgactcccg tcacccaagg cccctctgtc 1700

 atcacaacca ccagcatgca cacggtggga cccatccgca ggcggtactc 1750

 agacaaatac aacgtgccca tttcgtcagc agatattgcg cagaaccaag 1800

 aattttataa gaacgcagaa gttagaccac catttacata tgcatcttta 1850

 attaggcagg ccattctcga atctccagaa aagcagctaa cactaaatga 1900

 gatctataac tggttcacac gaatgtttgc ttacttccga cgcaacgcgg 1950

 ccacgtggaa gaatgcagtg cgtcataatc ttagtcttca caagtgtttt 2000

 gtgcgagtag aaaacgttaa aggggcagta tggacagtgg atgaagtaga 2050

 attccaaaaa cgaaggccac aaaagatcag tggtaaccct tcccttatta 2100

 aaaacatgca gagcagccac gcctactgca cacctctcaa tgcagcttta 2150

 caggcttcaa tggctgagaa tagtatacct ctatacacta ccgcttccat 2200

 gggaaatccc actctgggca acttagccag cgcaatacgg gaagagctga 2250

 acggggcaat ggagcatacc aacagcaacg agagtgacag cagtccaggc 2300

 agatctccta tgcaagccgt gcatcctgta cacgtcaaag aagagcccct 2350

 cgatccagag gaagctgaag ggcccctgtc cttagtgaca acagccaacc 2400

 acagtccaga ttttgaccat gacagagatt acgaagatga accagtaaac 2450

 gaggacatgg agtgactatc ggggcgggcc aaccccgaga atgaagattg 2500

 gaaaaaggaa aaaaaaaaaa cacgtcaaaa gttagcagtg aaattgttct 2550

 ccatttgttg tacagtctgg aggattttca ctacgttttg acaactctga 2600

 aatgtgttaa ctcttagtgc catcaagaac cccatttggg agtatttttg 2650

 atttttctac tttttgttga aaaaaggaat ttgtactctg tgcattggat 2700

 ggacttgttt ggtacttggg attttcctct cttaaccgtc aacatcagtg 2750

 ttgtaaattt gctaaactga ttcactttta gcagcagact ttgaactgca 2800

 gtcctgccaa cgttggacac tgaggacgcc cgacagagct tgtgcaccta 2850

 agctgcagac caagcctttg cccagaattt aaggattcca atggacgacc 2900

 tatttgcaca gtactgcatg ttgattatca ctgcctttac tccttttttt 2950

 tttttttttt tttttttgct tccagttggg atggggaagg cctttgtgtg 3000

 tgtattgggg ggaggggtta aaaaataatt atcccaaact ttttaatgta 3050

 ttgctttttt tttttttttc cttctactat accattttaa gttctgacct 3100

 caggcctcca tttgggccga tggcctcttg gaggcttaaa gttttctgta 3150

 ccttgtgatg aatgttaata ggtgttttta ttatacaaag ctgaatgtca 3200

 tttctcgttt gtagctttct gtcactcatt ccatcttcct tcagacatca 3250

 ccacgtttct ctaaagtcag aaaacattcc gttttggtct ttttcaaaaa 3300

 ggtcccaaat gctgcactct acacatgaag gccctctcac acagacgtga 3350

 cgtcctgcca gaaagagaat gaatgacaga aaaaaaaaag agagacaaac 3400

 tctaggaaca atgccgattc attccacgca gcagtattgg gggtggttcg 3450

 ggggaggggt gtttcggatt ttcttttttt cttttctttt attttttttt 3500

 ttttgcagca accattaata aatgccacca cattctacca gcacaaggaa 3550

 acataggcag cactgaaaaa aaaaaaaaag ctcatattaa ttagactgac 3600

 aatatggcct tggaaggctc tcccttgtgg aaccaagttg ccatgggcct 3650

 tgggtgctct gcgataacgg gtgtgggttg gttttgtttg caaaatggcc 3700

 aaaaaaaaaa ccggcttccc cgagcagctg ccctgaaagt aggggtggcg 3750

 gcggcggcgc tgagtttata cattagttca gacctacttg gtggcattaa 3800

 actgtttgaa tgcaaattcg atttcagatt gaacttgtta agggagttaa 3850

 cgagggctga gttcagcaaa tgctaaagtg ttaatttcaa atatgcaaat 3900

 ttggtactgc agtttgttat gcaatattat atcaccaacc cagtatcaca 3950

 aaaactcata gaagatatca tgtaggccct gggctttggg ggggtcccaa 4000

 acatggtatg cagaaatgtg atggttacag gtcagtacaa cctcagtcct 4050

 tagaacccct ccacacttca gctctgcacc cactttcctg tcatttattt 4100

 atataggact gtagtttttt ttagttcgag agcctttcga agcttaattt 4150

 atattctttc tttgtacctt ttttctaaaa ttaccaaaga tattacacaa 4200

 aggtaaatta tgttctctgt tttatgcttt atctgatgaa gccaaatatc 4250

 ctcttattgt tgatcaaagg aggcaaaaga atttagaggc aaatgacaag 4300

 cgataggcta ttgcaacctg agaaagagaa ctgctccttc atcgtaaatt 4350

 tagaagacca agtagataat ggaaccaaag ttgtactttt ttctagtagt 4400

 tatttttcct ttttcttttt gtgtacctct acagagacca aaactcattc 4450

 tcttaaagag attttatggg gctactgcag ataaaaatag gacacaatat 4500

 taaaggagct acagaaggaa gggagtccca tctcaaaaaa aaaatgaatg 4550

 tatgccactg caattagagt atccaataaa ggagacagtt tagagtcagg 4600

 acagaaaagc ttccataatt gaactagatt acataatagt atttctagaa 4650

 aaagagatat ttttagattg tatgccactt ttgtttaaga actgtgctgt 4700

 gatcactgta ttaattttgg tttatcttgg catatatcct tcagtttgtt 4750

 tttattttta atttttcctt tttttccgat taggctttgg tcagcatttt 4800

 tcatttaaag aaaagtaaca ctcccatcca ctcataagct tggtacaaaa 4850

 acttctctgg cagttacttt tgaagcttca ctctgctttc tgtataaagg 4900

 gcagtctgtg gtcacgcaag acttaaaaaa aaaaaaaaaa aaaaaaaaaa 4950

 aaaa 4954

<210> 4093
<211> 677
<212> PRT
<213> Homo sapien

<400> 4093
 Met Met Gln Glu Ser Gly Thr Glu Thr Lys Ser Asn Gly Ser Ala
   1               5                  10                  15

 Ile Gln Asn Gly Ser Gly Gly Ser Asn His Leu Leu Glu Cys Gly
                  20                  25                  30

 Gly Leu Arg Glu Gly Arg Ser Asn Gly Glu Thr Pro Ala Val Asp
                  35                  40                  45

 Ile Gly Ala Ala Asp Leu Ala His Ala Gln Gln Gln Gln Gln Gln
                  50                  55                  60

 Ala Leu Gln Val Ala Arg Gln Leu Leu Leu Gln Gln Gln Gln Gln
                  65                  70                  75

 Gln Gln Val Ser Gly Leu Lys Ser Pro Lys Arg Asn Asp Lys Gln
                  80                  85                  90

 Pro Ala Leu Gln Val Pro Val Ser Val Ala Met Met Thr Pro Gln
                  95                 100                 105

 Val Ile Thr Pro Gln Gln Met Gln Gln Ile Leu Gln Gln Gln Val
                 110                 115                 120

 Leu Ser Pro Gln Gln Leu Gln Val Leu Leu Gln Gln Gln Gln Ala
                 125                 130                 135

 Leu Met Leu Gln Gln Gln Gln Leu Gln Glu Phe Tyr Lys Lys Gln
                 140                 145                 150

 Gln Glu Gln Leu Gln Leu Gln Leu Leu Gln Gln Gln His Ala Gly
                 155                 160                 165

 Lys Gln Pro Lys Glu Gln Gln Gln Val Ala Thr Gln Gln Leu Ala
                 170                 175                 180

 Phe Gln Gln Gln Leu Leu Gln Met Gln Gln Leu Gln Gln Gln His
                 185                 190                 195

 Leu Leu Ser Leu Gln Arg Gln Gly Leu Leu Thr Ile Gln Pro Gly
                 200                 205                 210

 Gln Pro Ala Leu Pro Leu Gln Pro Leu Ala Gln Gly Met Ile Pro
                 215                 220                 225

 Thr Glu Leu Gln Gln Leu Trp Lys Glu Val Thr Ser Ala His Thr
                 230                 235                 240

 Ala Glu Glu Thr Thr Gly Asn Asn His Ser Ser Leu Asp Leu Thr
                 245                 250                 255

 Thr Thr Cys Val Ser Ser Ser Ala Pro Ser Lys Thr Ser Leu Ile
                 260                 265                 270

 Met Asn Pro His Ala Ser Thr Asn Gly Gln Leu Ser Val His Thr
                 275                 280                 285

 Pro Lys Arg Glu Ser Leu Ser His Glu Glu His Pro His Ser His
                 290                 295                 300

 Pro Leu Tyr Gly His Gly Val Cys Lys Trp Pro Gly Cys Glu Ala
                 305                 310                 315

 Val Cys Glu Asp Phe Gln Ser Phe Leu Lys His Leu Asn Ser Glu
                 320                 325                 330

 His Ala Leu Asp Asp Arg Ser Thr Ala Gln Cys Arg Val Gln Met
                 335                 340                 345

 Gln Val Val Gln Gln Leu Glu Leu Gln Leu Ala Lys Asp Lys Glu
                 350                 355                 360

 Arg Leu Gln Ala Met Met Thr His Leu His Val Lys Ser Thr Glu
                 365                 370                 375

 Pro Lys Ala Ala Pro Gln Pro Leu Asn Leu Val Ser Ser Val Thr
                 380                 385                 390

 Leu Ser Lys Ser Ala Ser Glu Ala Ser Pro Gln Ser Leu Pro His
                 395                 400                 405

 Thr Pro Thr Thr Pro Thr Ala Pro Leu Thr Pro Val Thr Gln Gly
                 410                 415                 420

 Pro Ser Val Ile Thr Thr Thr Ser Met His Thr Val Gly Pro Ile
                 425                 430                 435

 Arg Arg Arg Tyr Ser Asp Lys Tyr Asn Val Pro Ile Ser Ser Ala
                 440                 445                 450

 Asp Ile Ala Gln Asn Gln Glu Phe Tyr Lys Asn Ala Glu Val Arg
                 455                 460                 465

 Pro Pro Phe Thr Tyr Ala Ser Leu Ile Arg Gln Ala Ile Leu Glu
                 470                 475                 480

 Ser Pro Glu Lys Gln Leu Thr Leu Asn Glu Ile Tyr Asn Trp Phe
                 485                 490                 495

 Thr Arg Met Phe Ala Tyr Phe Arg Arg Asn Ala Ala Thr Trp Lys
                 500                 505                 510

 Asn Ala Val Arg His Asn Leu Ser Leu His Lys Cys Phe Val Arg
                 515                 520                 525

 Val Glu Asn Val Lys Gly Ala Val Trp Thr Val Asp Glu Val Glu
                 530                 535                 540

 Phe Gln Lys Arg Arg Pro Gln Lys Ile Ser Gly Asn Pro Ser Leu
                 545                 550                 555

 Ile Lys Asn Met Gln Ser Ser His Ala Tyr Cys Thr Pro Leu Asn
                 560                 565                 570

 Ala Ala Leu Gln Ala Ser Met Ala Glu Asn Ser Ile Pro Leu Tyr
                 575                 580                 585

 Thr Thr Ala Ser Met Gly Asn Pro Thr Leu Gly Asn Leu Ala Ser
                 590                 595                 600

 Ala Ile Arg Glu Glu Leu Asn Gly Ala Met Glu His Thr Asn Ser
                 605                 610                 615

 Asn Glu Ser Asp Ser Ser Pro Gly Arg Ser Pro Met Gln Ala Val
                 620                 625                 630

 His Pro Val His Val Lys Glu Glu Pro Leu Asp Pro Glu Glu Ala
                 635                 640                 645

 Glu Gly Pro Leu Ser Leu Val Thr Thr Ala Asn His Ser Pro Asp
                 650                 655                 660

 Phe Asp His Asp Arg Asp Tyr Glu Asp Glu Pro Val Asn Glu Asp
                 665                 670                 675

 Met Glu


<210> 4094
<211> 3957
<212> DNA
<213> Homo sapien

<400> 4094
 gcgccggggc cgggtagctg ctccaggcgc gcgagctaac cgagtgcggc 50

 gagggcctac caggggcgac agggtttctc tccgcaagcg cgcgatgcag 100

 cgggcggcgg cgctggtccg gcggggctgt ggtccccgga cccccagctc 150

 ctggggccgc agccagagca gcgcggccgc cgaggcctcg gcggtgctca 200

 aggtgcggcc cgagcgcagc cggcgcgagc gcatcctcac gctggagtcc 250

 atgaacccgc aggtgaaggc ggtggagtac gccgtgcggg gacccatcgt 300

 gctcaaggcc ggcgagatcg agctcgagct gcagcggggt atcaaaaagc 350

 cattcacaga ggtcatccga gccaacatcg gggacgccca ggctatgggg 400

 cagcagccaa tcaccttcct ccggcaggtg atggcactat gcacctaccc 450

 aaacctgctg gacagcccca gcttcccaga agatgctaag aaacgtgccc 500

 ggcggatcct gcaggcttgt ggcgggaaca gcctggggtc ctacagtgct 550

 agccagggtg tcaactgcat ccgtgaagat gtggctgcct acatcaccag 600

 gagggatggc ggtgtgcctg cggaccccga caacatctac ctgaccacgg 650

 gagctagtga cggcatttct acgatcctga agatcctcgt ctccgggggc 700

 ggcaagtcac ggacaggtgt gatgatcccc atcccacaat atcccctcta 750

 ttcagctgtc atctctgagc tcgacgccat ccaggtgaat tactacctgg 800

 acgaggagaa ctgctgggcg ctgaatgtga atgagctccg gcgggcggtg 850

 caggaggcca aagaccactg tgatcctaag gtgctctgca taatcaaccc 900

 tgggaacccc acaggccagg tacaaagcag aaagtgcata gaagatgtga 950

 tccactttgc ctgggaagag aagctctttc tcctggctga tgaggtgtac 1000

 caggacaacg tgtactctcc agattgcaga ttccactcct tcaagaaggt 1050

 gctgtacgag atggggcccg agtactccag caacgtggag ctcgcctcct 1100

 tccactccac ctccaagggc tacatgggcg agtgtggtta cagaggaggc 1150

 tacatggagg tgatcaacct gcaccctgag atcaagggcc agctggtgaa 1200

 gctgctgtcg gtgcgcctgt gccccccagt gtctgggcag gccgccatgg 1250

 acattgtcgt gaaccccccg gtggcaggag aggagtcctt tgagcaattc 1300

 agccgagaga aggagtcggt cctgggtaat ctggccaaaa aagcaaagct 1350

 gacggaagac ctgtttaacc aagtcccagg aattcactgc aaccccttgc 1400

 agggggccat gtacgccttc cctcggatct tcattcctgc caaagctgtg 1450

 gaggctgctc aggcccatca aatggctcca gacatgttct actgcatgaa 1500

 gctcctggag gagactggca tctgtgtcgt gcccggcagt ggctttgggc 1550

 agagggaagg cacttaccac ttcaggatga ctatcctccc tccagtggag 1600

 aagctgaaaa cggtgctgca gaaggtgaaa gacttccaca tcaacttcct 1650

 ggagaagtac gcgtgaggac gcctgagccc cagcgggaga cctgtccttg 1700

 gctcttcctc ccaatgcccg tcaggctgaa ctcgcctccc ccgtgactct 1750

 gcctcgggcc tcgcagaggc cgctggtcac ttcgtcatca ttttgcccct 1800

 ggagacgtct ttctttgtgc cttgatgttg agagcgcctc tcttttgagc 1850

 aaacaagcat tctatatgca accagagtag aggggacctg ctcagcaggt 1900

 gtgaccaggg ttctctgaat ctgttattgt ttttgcttct ggaaagttca 1950

 tttggggttt acaacaacta ggatgtgttg ggtgagatgt ttcagatctg 2000

 gagaaatgag caggtgtcgg gaaatgtgtg acttaaccgt ggtgagggct 2050

 ggaaatccaa actcaccacc atgatctgtg aaataaagcc cttagcggtg 2100

 tgaagcatcc ggtcctttga acagaagggc ctggaaggcc cctggggctg 2150

 agaaagggtc cgcccggtgg cctggaggca ggcgccggga gcgcagtagc 2200

 acgtggactg ggcaggatgt tgcactagct tggggtagat gctgggggct 2250

 gcggccacgg tcagagggcc ccactgtgag gcgtgggtgt gagccaggct 2300

 gcaggaggaa ctgggcctcc gcttcccagc aacgcagcca ggcctgagaa 2350

 ttctgtgcgc ccggcgggct ttgggaatga ggggttccct tgaacatgcg 2400

 taggctggaa ccccgtctga gaggtctccc tgaatttcag tgacacatag 2450

 tgcagcccgg cagtgtccca cttccgtgga gagagccgct ggaatggtgt 2500

 ggacccatcc cgcgggtgac cggtgcctgt tctcccctga ccgagcctgt 2550

 gagcacatcg ccccctgctg gcgacagcgg ggaaatgagg gctgaaaata 2600

 tcctccccac aagggcaatc cccgggacct gccgagcagc caaggccctg 2650

 tcctttcttg aatggtggcg agctgaatct ggtcggtttc ctagctttta 2700

 ggtggtaaaa gtgcctggca gcttggctgc cgtggaggag tcagtcgtgg 2750

 ttggaggttc attgccgtgc tttcatgcag agtgttttgc cttcatgtta 2800

 gcttccggct cccctcccag gctgcagact ctgacctgtg gcatcaggct 2850

 tctcccagta caggagggtg ccatccccca gcatgcggct tctctgccat 2900

 tagcagccct gggcgggccg accacactcg aggctgcggt gctacgggct 2950

 tagccctcgc ctccctcact gggagcttcc ccatcctccc tgccttcccc 3000

 agtgggaagt tagggaagct caggagcctg ggaccccgca tgtcccaaaa 3050

 tgggattgga gaagctggag agaaagcaga agaggccgag gagtgaggca 3100

 gcagcctcta tgcttgattt ccacaccggg tccgtgcaga ggaaacagaa 3150

 actcccaact gtccttaccc accgacatca cagcccctat gaagaaagta 3200

 gccacaatct caaataacaa aagggaatgt tctaaaactt tttcttcctt 3250

 aaaaaatgga gaaaattgca cttgtgcttg ctgtgtggta tataaaccag 3300

 gattagtccc agggtcgtga ggtttctggt gaaaaggtta aatcgtagaa 3350

 gctagtatat tttttatatt tttgtaacaa ttgctttttt catgggggag 3400

 gcggggttag tatttatagt cctaacaagt ccagtaattt tttataaatc 3450

 ttcagattat aaacagcccc taaaaacttt acaacgttta cacagttttt 3500

 taaaaagaga ctgtatacac ttgatttgct ttcaaaataa ataaggtcag 3550

 ctagtctagg aggttaacgt cgggtaggaa tgctgatcat gataggtttg 3600

 gttttctaca gattctgttc cggtgccttt cctatccagg caccacctga 3650

 gaaagttgtc atttgaggtc gcacttggaa gttacatctg tgaagtttct 3700

 gtcattcgtc cagatctgtg tgtgtagcat gtgctgagga agcacgtgct 3750

 gggctgtgcc tcagacagtg catcaccggg cacccagagg cttgcctggc 3800

 tattcctgtt ctggtgtgtg tggagtgttg gggaggaaca gatgcagatc 3850

 aacctgtggc tgttttcccg tctaggttct cacaggtatc tcctgacaga 3900

 ggtacttaac aatggctctg ctggaaattt ctataaataa aatgtccaaa 3950

 atggaaa 3957

<210> 4095
<211> 523
<212> PRT
<213> Homo sapien

<400> 4095
 Met Gln Arg Ala Ala Ala Leu Val Arg Arg Gly Cys Gly Pro Arg
   1               5                  10                  15

 Thr Pro Ser Ser Trp Gly Arg Ser Gln Ser Ser Ala Ala Ala Glu
                  20                  25                  30

 Ala Ser Ala Val Leu Lys Val Arg Pro Glu Arg Ser Arg Arg Glu
                  35                  40                  45

 Arg Ile Leu Thr Leu Glu Ser Met Asn Pro Gln Val Lys Ala Val
                  50                  55                  60

 Glu Tyr Ala Val Arg Gly Pro Ile Val Leu Lys Ala Gly Glu Ile
                  65                  70                  75

 Glu Leu Glu Leu Gln Arg Gly Ile Lys Lys Pro Phe Thr Glu Val
                  80                  85                  90

 Ile Arg Ala Asn Ile Gly Asp Ala Gln Ala Met Gly Gln Gln Pro
                  95                 100                 105

 Ile Thr Phe Leu Arg Gln Val Met Ala Leu Cys Thr Tyr Pro Asn
                 110                 115                 120

 Leu Leu Asp Ser Pro Ser Phe Pro Glu Asp Ala Lys Lys Arg Ala
                 125                 130                 135

 Arg Arg Ile Leu Gln Ala Cys Gly Gly Asn Ser Leu Gly Ser Tyr
                 140                 145                 150

 Ser Ala Ser Gln Gly Val Asn Cys Ile Arg Glu Asp Val Ala Ala
                 155                 160                 165

 Tyr Ile Thr Arg Arg Asp Gly Gly Val Pro Ala Asp Pro Asp Asn
                 170                 175                 180

 Ile Tyr Leu Thr Thr Gly Ala Ser Asp Gly Ile Ser Thr Ile Leu
                 185                 190                 195

 Lys Ile Leu Val Ser Gly Gly Gly Lys Ser Arg Thr Gly Val Met
                 200                 205                 210

 Ile Pro Ile Pro Gln Tyr Pro Leu Tyr Ser Ala Val Ile Ser Glu
                 215                 220                 225

 Leu Asp Ala Ile Gln Val Asn Tyr Tyr Leu Asp Glu Glu Asn Cys
                 230                 235                 240

 Trp Ala Leu Asn Val Asn Glu Leu Arg Arg Ala Val Gln Glu Ala
                 245                 250                 255

 Lys Asp His Cys Asp Pro Lys Val Leu Cys Ile Ile Asn Pro Gly
                 260                 265                 270

 Asn Pro Thr Gly Gln Val Gln Ser Arg Lys Cys Ile Glu Asp Val
                 275                 280                 285

 Ile His Phe Ala Trp Glu Glu Lys Leu Phe Leu Leu Ala Asp Glu
                 290                 295                 300

 Val Tyr Gln Asp Asn Val Tyr Ser Pro Asp Cys Arg Phe His Ser
                 305                 310                 315

 Phe Lys Lys Val Leu Tyr Glu Met Gly Pro Glu Tyr Ser Ser Asn
                 320                 325                 330

 Val Glu Leu Ala Ser Phe His Ser Thr Ser Lys Gly Tyr Met Gly
                 335                 340                 345

 Glu Cys Gly Tyr Arg Gly Gly Tyr Met Glu Val Ile Asn Leu His
                 350                 355                 360

 Pro Glu Ile Lys Gly Gln Leu Val Lys Leu Leu Ser Val Arg Leu
                 365                 370                 375

 Cys Pro Pro Val Ser Gly Gln Ala Ala Met Asp Ile Val Val Asn
                 380                 385                 390

 Pro Pro Val Ala Gly Glu Glu Ser Phe Glu Gln Phe Ser Arg Glu
                 395                 400                 405

 Lys Glu Ser Val Leu Gly Asn Leu Ala Lys Lys Ala Lys Leu Thr
                 410                 415                 420

 Glu Asp Leu Phe Asn Gln Val Pro Gly Ile His Cys Asn Pro Leu
                 425                 430                 435

 Gln Gly Ala Met Tyr Ala Phe Pro Arg Ile Phe Ile Pro Ala Lys
                 440                 445                 450

 Ala Val Glu Ala Ala Gln Ala His Gln Met Ala Pro Asp Met Phe
                 455                 460                 465

 Tyr Cys Met Lys Leu Leu Glu Glu Thr Gly Ile Cys Val Val Pro
                 470                 475                 480

 Gly Ser Gly Phe Gly Gln Arg Glu Gly Thr Tyr His Phe Arg Met
                 485                 490                 495

 Thr Ile Leu Pro Pro Val Glu Lys Leu Lys Thr Val Leu Gln Lys
                 500                 505                 510

 Val Lys Asp Phe His Ile Asn Phe Leu Glu Lys Tyr Ala
                 515                 520

<210> 4096
<211> 3781
<212> DNA
<213> Homo sapien

<400> 4096
 gggccggctc gcgggcgctg ccagtctcgg gcggcggtgt ccggcgcgcg 50

 ggcggcctgc tgggcgggct gaagggttag cggagcacgg gcaaggcgga 100

 gagtgacgga gtcggcgagc ccccgcggcg acaggttctc tacttaaaag 150

 acaatgacta ctgatgaagg tgccaagaac aatgaagaaa gccccacagc 200

 cactgttgct gagcagggag aggatattac ctccaaaaaa gacaggggag 250

 tattaaagat tgtcaaaaga gtggggaatg gtgaggaaac gccgatgatt 300

 ggagacaaag tttatgtcca ttacaaagga aaattgtcaa atggaaagaa 350

 gtttgattcc agtcatgata gaaatgaacc atttgtcttt agtcttggca 400

 aaggccaagt catcaaggca tgggacattg gggtggctac catgaagaaa 450

 ggagagatat gccatttact gtgcaaacca gaatatgcat atggctcggc 500

 tggcagtctc cctaaaattc cctcgaatgc aactctcttt tttgagattg 550

 agctccttga tttcaaagga gaggatttat ttgaagatgg aggcattatc 600

 cggagaacca aacggaaagg agagggatat tcaaatccaa acgaaggagc 650

 aacagtagaa atccacctgg aaggccgctg tggtggaagg atgtttgact 700

 gcagagatgt ggcattcact gtgggcgaag gagaagacca cgacattcca 750

 attggaattg acaaagctct ggagaaaatg cagcgggaag aacaatgtat 800

 tttatatctt ggaccaagat atggttttgg agaggcaggg aagcctaaat 850

 ttggcattga acctaatgct gagcttatat atgaagttac acttaagagc 900

 ttcgaaaagg ccaaagaatc ctgggagatg gataccaaag aaaaattgga 950

 gcaggctgcc attgtcaaag agaagggaac cgtatacttc aagggaggca 1000

 aatacatgca ggcggtgatt cagtatggga agatagtgtc ctggttagag 1050

 atggaatatg gtttatcaga aaaggaatcg aaagcttctg aatcatttct 1100

 ccttgctgcc tttctgaacc tggccatgtg ctacctgaag cttagagaat 1150

 acaccaaagc tgttgaatgc tgtgacaagg cccttggact ggacagtgcc 1200

 aatgagaaag gcttgtatag gaggggtgaa gcccagctgc tcatgaacga 1250

 gtttgagtca gccaagggtg actttgagaa agtgctggaa gtaaaccccc 1300

 agaataaggc tgcaagactg cagatctcca tgtgccagaa aaaggccaag 1350

 gagcacaacg agcgggaccg caggatatac gccaacatgt tcaagaagtt 1400

 tgcagagcag gatgccaagg aagaggccaa taaagcaatg ggcaagaaga 1450

 cttcagaagg ggtcactaat gaaaaaggaa cagacagtca agcaatggaa 1500

 gaagagaaac ctgagggcca cgtatgacgc cacgccaagg agggaagagt 1550

 cccagtgaac tcggcccctc ctcaatgggc tttcccccaa ctcaggacag 1600

 aacagtgttt aatgtaaagt ttgttatagt ctatgtgatt ctggaagcaa 1650

 atggcaaaac cagtagcttc ccaaaaacag cccccctgct gctgcccgga 1700

 gggttcactg aggggtggca cgggaccact ccaggtggaa caaacagaaa 1750

 tgactgtggt gtggagggag tgagccagca gcttaagtcc agctcatttc 1800

 agtttctatc aaccttcaag tatccaattc agggtccctg gagatcatcc 1850

 taacaatgtg gggctgttag gttttacctt tgaactttca tagcactgca 1900

 gaaacctttt aaaaaaaaat gcttcatgaa tttctccttt cctacagttg 1950

 ggtagggtag gggaaggagg ataagctttt gttttttaaa tgactgaagt 2000

 gctataaatg tagtctgttg catttttaac caacagaacc cacagtagag 2050

 gggtctcatg tctccccagt tccacagcag tgtcacagac gtgaaagcca 2100

 gaacctcaga ggccacttgc ttgctgactt agcctcctcc caaagtcccc 2150

 ctcctcagcc agcctccttg tgagagtggc tttctaccac acacagcctg 2200

 tccctggggg agtaattctg tcattcctaa aacacccttc agcaatgata 2250

 atgagcagat gagagtttct ggattagctt ttcctatttt cgatgaagtt 2300

 ctgagatact gaaatgtgaa aagagcaatc agaattgtgc tttttctccc 2350

 ctcctctatt ccttttaggg aataatattc aatacacagt acttcctccc 2400

 agcattgcta ctgctcagct tcttctttca ttctaatcct tgctattaag 2450

 aatttaagac ttgtgcttac aatatttttg acctggagtg gatctattta 2500

 catagtcatt taggatccat gcagcttttt ttgtcttttt aagattattg 2550

 gctcataagc atatgtatac tggtttatgg aactttattt acactcctct 2600

 atcatgcaaa aaaattttga ctttttagta ctaagcttaa tttttaaaaa 2650

 caaaatctgt agtgttgaca aataaatagt tgctcttcta cactaggggt 2700

 ttcacctgca ggtttgacac gcagttgctc gcttttcctg ccctgtcaag 2750

 cttctctgtt ctggcgtgag ttgtgaaaga gttgaagaca gcttcccatg 2800

 ccggtacaca gccagtagcc taaatctcca gtacttgagc tgaccattga 2850

 actagggcaa gtcttaaatg tgtacatgta gttgaatttc agtccttacg 2900

 ggtaaacaga ttgagcatgg ctctctattc cctcagccta agaaacactc 2950

 atgggaatgc atttggcaac ccaaggaacc atttgcttaa acctggaaca 3000

 tctcaccttt ttaaatccta aaaaacactg gcagttatat tttaaattag 3050

 tttttatttt tatgatggtt ttatcaaaag acttttatta ttagattggg 3100

 acccccttca aacctaaaaa tcaagttatt tccttttata atacttttct 3150

 tccccatgga acaaatggga tcaatttgtg agttttttcc tttaatgata 3200

 actaaaatcc ctctaatttc tcatttatgc ttttgtcttt tttatgaaat 3250

 atttctttta aaagccccag tctcacctac gaaatatgaa gagcaaaagc 3300

 tgattttgct tacttgctaa actgttggga aagctctgta gagcatggtt 3350

 ccagtgaggc caagattgaa atttgatact aaaaaggcca cctagctttt 3400

 tgcagataac aaacaagaaa gctattccaa gactcagatg atgccagctg 3450

 tctcccacgt gtgtattatg gttcaccagg gggaactggc aaaagtgtgt 3500

 gtggggaggg gaagggtgtg tgagtggttc tgagcaaata actacagggt 3550

 gcccattacc actcaagaag acacttcacg tattcttgta tcaaattcaa 3600

 taatcttaaa caatttgtgt agaagtccac agacatcttt caaccacctt 3650

 ttaggctgca tatggattgc caagtcagca tatgaggaat taaagacatt 3700

 gtttttaaaa aaaaaaaatc atttagatgc acttttttgt gtgttcttta 3750

 aataaatcca aaaaaaatgt gaaaaaaaaa a 3781

<210> 4097
<211> 457
<212> PRT
<213> Homo sapien

<400> 4097
 Met Thr Thr Asp Glu Gly Ala Lys Asn Asn Glu Glu Ser Pro Thr
   1               5                  10                  15

 Ala Thr Val Ala Glu Gln Gly Glu Asp Ile Thr Ser Lys Lys Asp
                  20                  25                  30

 Arg Gly Val Leu Lys Ile Val Lys Arg Val Gly Asn Gly Glu Glu
                  35                  40                  45

 Thr Pro Met Ile Gly Asp Lys Val Tyr Val His Tyr Lys Gly Lys
                  50                  55                  60

 Leu Ser Asn Gly Lys Lys Phe Asp Ser Ser His Asp Arg Asn Glu
                  65                  70                  75

 Pro Phe Val Phe Ser Leu Gly Lys Gly Gln Val Ile Lys Ala Trp
                  80                  85                  90

 Asp Ile Gly Val Ala Thr Met Lys Lys Gly Glu Ile Cys His Leu
                  95                 100                 105

 Leu Cys Lys Pro Glu Tyr Ala Tyr Gly Ser Ala Gly Ser Leu Pro
                 110                 115                 120

 Lys Ile Pro Ser Asn Ala Thr Leu Phe Phe Glu Ile Glu Leu Leu
                 125                 130                 135

 Asp Phe Lys Gly Glu Asp Leu Phe Glu Asp Gly Gly Ile Ile Arg
                 140                 145                 150

 Arg Thr Lys Arg Lys Gly Glu Gly Tyr Ser Asn Pro Asn Glu Gly
                 155                 160                 165

 Ala Thr Val Glu Ile His Leu Glu Gly Arg Cys Gly Gly Arg Met
                 170                 175                 180

 Phe Asp Cys Arg Asp Val Ala Phe Thr Val Gly Glu Gly Glu Asp
                 185                 190                 195

 His Asp Ile Pro Ile Gly Ile Asp Lys Ala Leu Glu Lys Met Gln
                 200                 205                 210

 Arg Glu Glu Gln Cys Ile Leu Tyr Leu Gly Pro Arg Tyr Gly Phe
                 215                 220                 225

 Gly Glu Ala Gly Lys Pro Lys Phe Gly Ile Glu Pro Asn Ala Glu
                 230                 235                 240

 Leu Ile Tyr Glu Val Thr Leu Lys Ser Phe Glu Lys Ala Lys Glu
                 245                 250                 255

 Ser Trp Glu Met Asp Thr Lys Glu Lys Leu Glu Gln Ala Ala Ile
                 260                 265                 270

 Val Lys Glu Lys Gly Thr Val Tyr Phe Lys Gly Gly Lys Tyr Met
                 275                 280                 285

 Gln Ala Val Ile Gln Tyr Gly Lys Ile Val Ser Trp Leu Glu Met
                 290                 295                 300

 Glu Tyr Gly Leu Ser Glu Lys Glu Ser Lys Ala Ser Glu Ser Phe
                 305                 310                 315

 Leu Leu Ala Ala Phe Leu Asn Leu Ala Met Cys Tyr Leu Lys Leu
                 320                 325                 330

 Arg Glu Tyr Thr Lys Ala Val Glu Cys Cys Asp Lys Ala Leu Gly
                 335                 340                 345

 Leu Asp Ser Ala Asn Glu Lys Gly Leu Tyr Arg Arg Gly Glu Ala
                 350                 355                 360

 Gln Leu Leu Met Asn Glu Phe Glu Ser Ala Lys Gly Asp Phe Glu
                 365                 370                 375

 Lys Val Leu Glu Val Asn Pro Gln Asn Lys Ala Ala Arg Leu Gln
                 380                 385                 390

 Ile Ser Met Cys Gln Lys Lys Ala Lys Glu His Asn Glu Arg Asp
                 395                 400                 405

 Arg Arg Ile Tyr Ala Asn Met Phe Lys Lys Phe Ala Glu Gln Asp
                 410                 415                 420

 Ala Lys Glu Glu Ala Asn Lys Ala Met Gly Lys Lys Thr Ser Glu
                 425                 430                 435

 Gly Val Thr Asn Glu Lys Gly Thr Asp Ser Gln Ala Met Glu Glu
                 440                 445                 450

 Glu Lys Pro Glu Gly His Val
                 455

<210> 4098
<211> 4055
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 484, 495, 546, 567, 615, 1221, 1411, 2798, 3467, 3516
<223> Unknown base

<400> 4098
 cttttcgagg taggagtcga ctcctgtgag gtatgtttta tctttgcgaa 50

 tgttgcgggt tttggggcgc tccagccttt gtctgctaag gtcaccctga 100

 attgactggg acttctaagc cagtcgcgcg cctttgcagg gcctacaagt 150

 tgaggatggt gggggattgc acatatggtg catgcgtgac ctaagctgcg 200

 actatgttag agtagaactg cggagaagcc tcggctctcg tgccctgcct 250

 ctgatgaagc ctgtgttggt agggacatct gacagtaatg atgaatgcca 300

 accgctctga tggtggcaca tgccgagtca cccgagtaag ctattgttaa 350

 gggccgtgac ccgagcctcc atcagccgtc cgctctcatg aaaggctgtc 400

 ggtggtagtc cacgtgctta agtgcctgca ttccgcagtg tcaccaatat 450

 ttccattagt gtttcttttt tcttttttga gacngagcct cgttntgtca 500

 cccaggctgg aatgcagtgg ctcgacatcg gttaatggca acctcngcgt 550

 cccgagttaa gcagttntgc ctcagcctcc caagtaactg ggactacagg 600

 cgcgcgccac catgntaggc ttttatattt ttagtagaga cggggtttca 650

 ccatgttggc gagactggtc ttgaactcct gacctcaggt gatccaccag 700

 ccgtggtccc ccaacatact gggattacaa gccgtgagcc accgcgcccg 750

 gccgccatcg gtggttctta actgcgggtg cagtgcttct ttgtaacatt 800

 aagtgtatcc tttacctgtc gctagataat gaatggtatg ttacctgcat 850

 cattggttta aaaagacgaa ccgttttttt aaagaacact ctttaaaaaa 900

 aagaaccgtg gaacaatgaa ttaaaatctg tacctgatct ctttaggtat 950

 ggtgctgggt gcagatgcag tgtggctctg gatagcacct tatggacagg 1000

 taagaattgg ggaaagtatg gtgggaagaa tgaaatctaa gaggtggtct 1050

 cagcctgtga tgctttaaga gtagtggaca gaagggattt ctgaaattct 1100

 attctgaggc tttaatgtta acagcattta tatttaacgt gactgctgtg 1150

 aggttcattc tcactgtttt gcttgcatct ttttgttttc tagttgtgtc 1200

 cccaaggaag gatgagaata nctactgaag taagttgaaa attccctctc 1250

 aaaaaggttt aaagccattg gatgtgccac aatgatgaca gtttatttgc 1300

 tactcttgag tgctagaatg atgaggatct taaccaccat tatcttaact 1350

 gaggcaccaa aatggtgagt tggggaacat agagagtaca cctaattcac 1400

 atgaatttgt ntcttcccag gtcctaaaga gcaagcctaa ctcaagccat 1450

 tggcacacag gtgagacact tctattttgt acttctcact tttaagggat 1500

 tagaaaatag ccaaagcaat gatgattatc tatgttagtg cttctctccc 1550

 ctcttttcaa atgagaattt tgctctcata ttgatactaa gtttaatact 1600

 gaagaaaatg tgaaaacaga tactatgatg gttgcatagt tcagcagatt 1650

 taatcatgaa gagatgtact atctgtctga tgtatctggg gtagttgtgg 1700

 tttgctgtta atggttaagc agtgtaccac caatctacca ttaaaatatt 1750

 ttttgctgac aattttgtat taaaattaca ggcattagac agaaagctgg 1800

 aagttgaaat ggtaagtgaa actgtatcca agtaagcagg taactgggca 1850

 aacttcctac ggcacaaatg gctttttagt tacctcctag tgctgaatgc 1900

 attaaataaa tggcggattc ttgtcttgtt atgattaata agaaagtttg 1950

 taaatgcagc ctggatgatg atagcaaatg ctgactgaac atgaaggtct 2000

 taattagctc taactgacta aaggcatttg ttagctttgg cagggggtga 2050

 acactcatct gtggctattc taagaccact cttatttctt aggtggagtc 2100

 caacttgcct ggaccagctt aatggttctg gtaagtatta atgaaaacag 2150

 tagatagact taatgaaaat gctgatggtg atatgcttac tgctgagcta 2200

 atggcttaag gcttggctga tgaatactga ctgtattttc cttgagcatg 2250

 tctggaacag tgtttatgtg ttttccttga gcatgtttgg aacggggttt 2300

 gtgtaatgat gttgatcaaa tgtctgacct gaaatgagca tgtagacaaa 2350

 ggtacactga agaacctgtg acagacaact ttgaaaagag tttaatgatg 2400

 tttagcattt taatggaagt cctcatttgt attccagctc ctggtaacgt 2450

 ttttatccat ggatgacttg cttgggtaag gacatgaaga cagttcctgt 2500

 catacctttt aaaggtacat gttttattga tgttaacgtt aattgattga 2550

 gctactgtta gtgatgattt taaaattaaa gcagatggga atccctctga 2600

 gaaagaaaat ggagattaat cttaaactga aacagtagtt gggaaatctt 2650

 ttagaaatcc acctattact acctattggt aaaggagatt aaatttctac 2700

 aggtatggag agtcggcttg actacactgt gtggagcaag ttttaaagaa 2750

 gcaaaggtat agcagttcca agtatttttt ttttttttta gacaagantc 2800

 tagctcttgc ccagaatgga gtgcagcggc actatcagtt cgctgcaacc 2850

 tctgcctccc aggttcaagg aattctcctg cctcagcctc ttgagtagct 2900

 gggattacag gcatgtgaca ccatgcctgg ctaattttgt acagctatgt 2950

 tgtccaggct ggtctcgaac tcttgacctc aagtgacact gcccgcactg 3000

 acctcccaaa gtgctgggat tacaggcgtg agccaccatg ccccgcctca 3050

 agtctggttt ttaagtgttg taaagccgat acaatgatga taacatagtt 3100

 cagcagacta acgctgatga gcaatattaa gtctttcgct cctatctgat 3150

 gtatctggcg gtaacattct agtttatgcc ccgaaaaggg gaatatagcc 3200

 attctataat gtttggagat tttggattac tcctaattgt atgcaagttg 3250

 tcttactgtg tattgtccct taatttcagg actcagaatt catgattgaa 3300

 gaaatgcagg ttagtttaaa ctttgaagga aattttaagg tggcaaaagg 3350

 ttttggtggc atatacacct taatctgtag atgggagtga ttagctgttt 3400

 aaaagttaaa atgtgactga gaaggaaatt gagtagggca aattttaaat 3450

 gggtattatt tttcatnttc aaacaggcag acctgttatc ctaaactagg 3500

 tgagtcagct tttggnacat gtgatgattt tcagtgtaac caatgatgta 3550

 atgattctgc caaatgaaat ataatgatat cactgtaaaa ccgttccatt 3600

 ttgattctga ggttactcta ctaacaagca tcacacattt gtattttgcc 3650

 ctgattaata tgttggcttc gctttcaggg tttttaatga ccacaacaag 3700

 caagcatgca gcttactgct tgaaaggtga ggattggaaa tgttgggact 3750

 attataattg cagaatacat gatgatctca atccaacttg aactctctca 3800

 ctgattactt gatgacaata aaatatctga tattctgcat tcccatgtag 3850

 cattttaatt gaagtctgta aatgtggcta aaagtcttgt cttatttttt 3900

 gagacagggt cttgcctcac ccaagctaga gtgcagtggc ctttgaagct 3950

 tactacagcc tcaaacttct gggctcaagt gatcctcagc ctcccagtgg 4000

 tctttgtaga ctgcctgatg gagtctcatg gcacaagaag attaaaacag 4050

 tgtct 4055

<210> 4099
<211> 1748
<212> DNA
<213> Homo sapien

<400> 4099
 ccacgcgtcc gctttctctt aggtttcagg aagactgtca catacagtaa 50

 gcttttttcc ttctgactta taatagaaaa tgttttgaaa gtaaaaaaaa 100

 aaaatctaat ttggaaattt gacttgttag tttctgtgtt tgaaatcatg 150

 gttctagaaa tgtagaaatt gtgtatatca gatactcatc taggctgtgt 200

 gaaccagccc aagatgacca acatccccac acctctacat ctctgtcccc 250

 tgtatctctt cctttctacc actaaagtgt tccctgctac catcctggct 300

 tgtccacatg gtgctctcca tcttcctcca catcatggac cacaggtgtg 350

 cctgtctagg cctggccacc actcccaact tgacctagcc acattcatct 400

 agagatggtt cctgatgctg ggcacagact gtgctcatgg cacccattag 450

 aaatgcctct agcatctttg tatgcatctt gatttttaaa ccaagtcatt 500

 gtacagagca ttcagttttg gctgtggtac caagagaaaa actaatcaag 550

 aatataaacc acattccagg ctgctgtttt ctctccatct acaggccaca 600

 cttttactgt atttcttcat acttgaaatt cattctgcta ttttcatatc 650

 agggtacaga cttataaggg tgcatgttcc ttaaaggtgc ataattattc 700

 ttattccgtt tgcttatatt gctacagaat gctctgtttt ggtgctttga 750

 gttctgcaga cccaagaagc agtgtggaaa ttcactgcct gggacacagt 800

 cttataagaa tgttggcagg tgactttgta tcagatgttg cttctctttt 850

 ctctgtacac agattgagag ttaccacagt ggcctgtcgg gtccaccctg 900

 tgggtgcagc acagctctct gaaagcaaga accttcctac ctattctaac 950

 gtttttgccc tctaagaaaa atggcctcag gtatggtata gacatagcaa 1000

 gaggggaagg gctgtctcac tctagcaacc atccctccat tacacacaga 1050

 aagccctctt gaagcaaaag aagaagaaag aaagaaagct tatctctaag 1100

 gctactgtct tcagaatgct ctgagctgaa tgctcttgct cctttcccaa 1150

 gaggcagatg aaaatatagc cagtttatct atacccttcc tatctgagga 1200

 ggagaataga aaagtagggt aaatatgtaa cgtaaaatat gtcattcaag 1250

 gaccaccaaa actttaagta ccctatcatt aaaaatctgg ttttaaaagt 1300

 agctcaagta agggatgctt tgtgacccag ggtttctgaa gtcagatagc 1350

 cattcttacc tgccccttac tctgacttat tgggaaaggg agaactgcag 1400

 tggtgtttct gttgcagtgg caaaggtaac atgtcagaaa attcagaggg 1450

 ttgcatacca ataatccttt ggaaactgga tgtcttactg ggtgctagaa 1500

 tgaaaatgta ggtatttatt gtcagatgat gaagttcatt gtttttttca 1550

 aaattggtgt tgaaatatca ctgtccaatg tgttcactta tgtgaaagct 1600

 aaattgaatg aggcaaaaag agcaaatagt ttgtatattt gtaatacctt 1650

 ttgtatttct tacaataaaa atattggtag caaataaaaa taataaaaac 1700

 aataacttta aactgcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1748

<210> 4100
<211> 62
<212> PRT
<213> Homo sapien

<400> 4100
 Met Thr Asn Ile Pro Thr Pro Leu His Leu Cys Pro Leu Tyr Leu
   1               5                  10                  15

 Phe Leu Ser Thr Thr Lys Val Phe Pro Ala Thr Ile Leu Ala Cys
                  20                  25                  30

 Pro His Gly Ala Leu His Leu Pro Pro His His Gly Pro Gln Val
                  35                  40                  45

 Cys Leu Ser Arg Pro Gly His His Ser Gln Leu Asp Leu Ala Thr
                  50                  55                  60

 Phe Ile


<210> 4101
<211> 8570
<212> DNA
<213> Homo sapien

<400> 4101
 gccttataag tggtttagtg ctcagttggc tctagtaacc agaggacaca 50

 gaaagtatct tttggaaagt ttagccacct gtgctttctg actcagagtg 100

 catgcaacag ttagatcatg caacagttag attatgttta gggttaggat 150

 tttcaaagaa tggaggttgc tgcactcaga aaataattca gatcatgttt 200

 atgcattatt aagttgtact gaattctttg cagcttaatg tgatatatga 250

 ctatcttgaa caagagaaaa aactaggaga tgtttctcct gaagagcttt 300

 tggggttggg aactattctt ttttaattgc tgtactactt aacattgttc 350

 taattcagta gcttgaggaa caggaacatt gttttctaga gcaagataat 400

 aaaggagatg ggccatacaa atgttttcta ctttcgttgt gacaacattg 450

 attaggtgtt gtcagtacta taaatgcttg agatataatg aatccacagc 500

 attcaaggtc aggtctactc aaagtctcac atggaaaagt gagttctgcc 550

 tttcctttga tcgagggtca aaatacaaag acatttttgc tagggcctac 600

 aaattgaatt taaaaactca ctgcactgat tcatctgagc ttttggttag 650

 tattcatggc tagagtgaac atagctttag tttttgctgt gtaaaagtgt 700

 tttcataagt tcactcaaga aaaatgcagc tgttctgaac tggaattttt 750

 cagcattctt tagaatttta aatgagtaga gagctcaact tttattccta 800

 gcatctgctt ttgactcatt tctaggcagt gcttatgaag aaaaattaaa 850

 gcacaaacat tctggcattc aatcgttggc agattatctt ctgatgacac 900

 agaatgaaag ggcatctcag cctctctgaa cttgtaaaaa tctgtcccca 950

 gttcttccat cggtgtagtt gttgcatttg agtgaatact ctcttgattt 1000

 atgtatttta tgtccagatt cgccatttct gaaatccaga tccaacacaa 1050

 gcagtcttgc cgttagggca ttttgaagca gatagtagag taagaactta 1100

 gtgactacag cttattcttc tgtaacatat ggtttcaaac atctttgcca 1150

 aaagctaagc agtggtgaag tgaaaagggc atattgcccc aaggttacac 1200

 tgaagcagct catagcaagt taaaatattg tgacagattt gaaatcatgt 1250

 ttgaatttca tagtaggacc agtacaagaa tgtccctgct agtttctgtt 1300

 tgatgtttgg ttctggcggc tcaggcattt tgggaactgt tgcacagggt 1350

 ggagtcaaaa caacctacat ataaaaagag aaaaagagaa acttgtccat 1400

 ttagctttca taagaaatcc catggcaaag ggtaataaaa aggacctaat 1450

 cttaaaaata caatttctaa gcacttgtaa gaacccagtg ggttggagcc 1500

 tcccactttg tccctccttt gaagtggatg ggaactcaag gtgcaaagaa 1550

 cctgttttgg aagaaagctt ggggccattt cagccccctg tattctcatg 1600

 attttctctc aggaagcaca cactgtgaat ggcagacttt tcatttagcc 1650

 ccaggtgact tactaaaaat agttgaaaat tattcaccta agaatagaat 1700

 ctcagcattg tgttaaataa aaatgaaagc tttagaaggc atgagatgtt 1750

 cctatcttaa ataaagcatg tttcttttct atagagaaat gtatagtttg 1800

 actctccaga atgtactatc catcttgatg agaaaactct taaatagtac 1850

 caaacatttt gaactttaaa ttatgtattt aaagtgagtg tttaagaaac 1900

 tgtagctgct tcttttacaa gtggtgccta ttaaagtcag taatggccat 1950

 tattgttcca ttgtggaaat taaattatgt aagcttccta atatcataaa 2000

 catattaaaa ttcttctaaa atattgcttt tcttttaagt gacaatttga 2050

 ctattcttat gataagcaca tgagagtgtc ttacattttc caaaagcagg 2100

 ctttaattgc atagttgagt ctaggaaaaa ataatgttaa aagtgaatat 2150

 gccaccataa ttacttaatt atgttagtat agaaactaca gaatatttac 2200

 cctggaaaga aaatattgga atgttattat aaactcttag atatttatat 2250

 aattcaaaag aatgcatgtt tcacattgtg acagataaag atgtatgatt 2300

 tctaaggctt taaaaattat tcataaaaca gtgggcaata gataaaggaa 2350

 attctggaga aaatgaaggt atttaaaggg tagtttcaaa gctatatata 2400

 ttttgaagga tatattcttt atgaacaaat atattgtaaa aatttatact 2450

 aaggtcatct ggtaactgtg ggattaatat ggtcgaaaac aaatgttatg 2500

 gagaagctgt cccaagcaaa ctaaattacc tgtacttttt tcccatttca 2550

 agggaagagg caaccacatg aagcaatact tcttacacat gcctaagaac 2600

 gttcattgaa aaaataaatt tttaaaaggc atgtgtttcc tatgccacca 2650

 atacttttga aaaattgtga accttaccca aaaccattta tcatgtccat 2700

 taagtatatt tgggtatata attaggaaga tatttacatg ttccatctcc 2750

 acagtggaaa aacttattga ggctaccaaa gtgtgccaag aaatgtaagt 2800

 ccttagagta attagaaatg ctgttttcct caaaagcatg agaaactagc 2850

 attttcattt cttatttact ccctttctat atcaatgcaa ttcacaaccc 2900

 aattttaata catccctata tctcaagcat ttctatcttg tactttttca 2950

 gaaaataaac caaaaataat ccttggtctc tctatcttct gaccttgtaa 3000

 gcaacagaaa tgtaaaaaca gaaggggtcc aatttttaca cgtttttttc 3050

 tcaagtagcc tttctgggga tttttatttt cttaatgaag tgccaatcag 3100

 cttttcaaaa tgttttctat ttctcagcat ttccaggaag tgataacgtt 3150

 tagctaaatg agtagaagtg gacttccttc aacatattgt taccttgtct 3200

 agccttagga agaaaacaag agccacctga aaataaatac aggctctttt 3250

 cgagcatctg ctgaaatact gttacagcaa tttgaagttg atgtggtagg 3300

 aaaggaaggt gacttttctt gcaaaagtct ttctaaacat tcacactgtc 3350

 ctaagagatg agctttcttg ttttattccg gtatattcca caaggtggca 3400

 cttttagaga aaaacaaatc tgatgaagac taaagaggta cttctaaaag 3450

 agatttcatt ctaactttat ttttctgcgc atatttaact ctttcctagc 3500

 acttgttttt tgggatgatt aatagtctct ataatgttct gtaacttcaa 3550

 tattttactt gttacctagg ttctgaacaa ttgtctgcaa ataaattgtt 3600

 cttaaggatg gataatacac ccattttgat catttaagta aagaaagcct 3650

 agtcattcat tcagtcaaga aaaaattttt gaagtaccca gttaccttac 3700

 ttttctagat taaaacaggc ttagttacta aaaaggcagt cctcatctgt 3750

 gaacaggata gtttcgttag aagtataaaa ctcctttagt ggccccagtt 3800

 aaaacacaca taccctctct gctgctttca aattccctag catggtggcc 3850

 tttcaacatt gattaaattt taaaatccta atttaaagat caggtgagca 3900

 aaatgagtag cacatcagta attcagtaga caaaactttt gtctgaaaaa 3950

 ttgctgtatt gaaacagagc cctaaaatac caaaagacca ggtaatttta 4000

 acatttgtgg aatcacaaat gtaaattcat aagaagctct aattaaaaaa 4050

 aaaaagtctg aagtatatga gcataacaac ttaggagtgt gtctacatac 4100

 ttaacttttg aagttttttg gcaactttat atactttttt taaatttaca 4150

 agtctactta aagacttctt ataccccaaa tgattaagtt aattttagag 4200

 gtcacctttc tcacagcagt gtcacttgaa atttagtagg gaaggatatt 4250

 gcagtatttt tcagtttcct tagcacagca ccacagaaag cagcttattc 4300

 cttttgagtg gcagacactc gacggtgcct gcccaacttt cctcctgagt 4350

 ggcaagcaga tgagtctcag taattcatac tgaaccaaaa tgccacatac 4400

 actaggggca gtcagaaact ggctgagaaa tcccccgcct cattcgcccc 4450

 tctgctccca ggaactagag tccagttaaa gcccctatgc gaaaggccga 4500

 attccacccc agggtttgtt ataacagtgg ccagtctgaa ccccatttgc 4550

 tcgtgctcaa aacttgattc ccacttgaaa gccttccggg cgcgctgcct 4600

 cgttgccccg cccctttggc aggagagagg cagtgggcga ggccgggctg 4650

 gggccccgcc tcccactcac ctgccggtgc ctgaaattat gtgcggcccc 4700

 gcgggctgct ttccgaggtc agagtgccct gctgctgtct cagaggcatc 4750

 tgttctgcaa atcttaggaa gaaaaatgtc cctagtagca aacgggtgtc 4800

 ttctgtgcat aaataagtac aacacaattc tccgaaagtt cgggtaaaaa 4850

 gagatgcggt agcagctgcc ctgtgtgaag ctgtctaccc cgcatctctc 4900

 aggcgctaag ctcagttttt gtttttgttt ttgttttttt aaagaaaaga 4950

 tgtataattg caggaatttt tttttatttt tttattttcc atcattctat 5000

 atatgtgatg gtgaaagata tgcctggaaa agttttgttt tgaaaagttt 5050

 attttctgct tcgtcttcag ttggcaaaag ctctcaattc tttagcttcc 5100

 agtttctttt ctctcttttt ctttgttagg taattaaagg tatgtaaaca 5150

 aattatctca tgtagcaggg gattttcatg ttgagaggaa tcttccgtgt 5200

 gagttgtttg gtcacacaaa taaccctttc tcaattttag gagtttggat 5250

 tgtcaaatgt aggtttttct caaagggggc atataactac atattgactg 5300

 ccaagaacta tgactgtagc actaatcagc acacatagag ccacacaatt 5350

 atttaatttc taactctctg tggtccctag aaaaattccg ttgatgtgct 5400

 taggttaaag ttctgaagat acccgttgta cccttacttg aaagtttcta 5450

 atcttaagtt ttatgaaatg caataatatg tatcagctag caatatttct 5500

 gtgatcacca acaactctca gtttgatctt aaagtctgaa taataaaaca 5550

 aatcccagca gtaatacatt tcttaaacct cacagtgcat gatatatctt 5600

 ttcattctga tcctgtgttt gcaaaaatat acacatgtat atcatagttc 5650

 ctcacttttt attcatttgt tttcctatta cctgtagtaa atatattagt 5700

 tagtacatgg aatttatagc atcagctacc cccaggaaca gcacctgaca 5750

 ggcgggggat tttttttcaa gttgttctac atttgcataa attatttcta 5800

 ttattattca tgtatgttat ttatttctga atcacactag tcctgtgaaa 5850

 gtacaactga aggcagaaag tgttaggatt ttgcatctaa tgttcattat 5900

 catggtattg atggacctaa gaaaataaaa attagactaa gcccccaaat 5950

 aagctgcatg catttgtaac atgattagta gatttgaata tatagatgta 6000

 gtattttggg tatctaggtg ttttatcatt atgtaaagga attaaagtaa 6050

 aggactttgt agttgttttt attaaatatg catatagtag agtgcaaaaa 6100

 tatagcaaaa ataaaaacta aaggtagaaa agcattttag atatgcctta 6150

 atttagaaac tgtgccaggt ggccctcgga atagatgcca ggcagagacc 6200

 agtgcctggg tggtgcctcc tcttgtctgc cctcatgaag aagcttccct 6250

 cacgtgatgt agtgccctcg taggtgtcat gtggagtagt gggaacaggc 6300

 agtactgttg agaggagagc agtgtgagag tttttctgta gaagcagaac 6350

 tgtcagcttg tgccttgagg cttccagaac gtgtcagatg gagaagtcca 6400

 agtttccatg cttcaggcaa cttagctgtg tacagaagca atccagtgtg 6450

 gtaataaaaa gcaaggattg cctgtataat ttattataaa ataaaaggga 6500

 ttttaacaac caacaattcc caacacctca aaagcttgtt gcattttttg 6550

 gtatttgagg tttttatctg aaggttaaag ggcaagtgtt tggtatagaa 6600

 gagcagtatg tgttaagaaa agaaaaatat tggttcgcgt agagtgcaaa 6650

 ttagaactag aaagttttat acgattatca ttttgagatg tgttaaagta 6700

 ggttttcact gtaaaatgta ttagtgtttc tgcattgcca tagggcctgg 6750

 ttaaaacttt ctcttaggtt tcaggaagac tgtcacatac agtaagcttt 6800

 tttccttctg acttataata gaaaatgttt tgaaagtaaa aaaaaaaaaa 6850

 tctaatttgg aaatttgact tgttagtttc tgtgtttgaa atcatggttc 6900

 tagaaatgta gaaattgtgt atatcagata ctcatctagg ctgtgtgaac 6950

 cagcccaaga tgaccaacat ccccacacct ctacatctct gtcccctgta 7000

 tctcttcctt tctaccacta aagtgttccc tgctaccatc ctggcttgtc 7050

 cacatggtgc tctccatctt cctccacatc atggaccaca ggtgtgcctg 7100

 tctaggcctg gccaccactc ccaacttgac ctagccacat tcatctagag 7150

 atggttcctg atgctgggca cagactgtgc tcatggcacc cattagaaat 7200

 gcctctagca tctttgtatg catcttgatt tttaaaccaa gtcattgtac 7250

 agagcattca gttttggctg tggtaccaag agaaaaacta atcaagaata 7300

 taaaccacat tccaggctgc tgttttctct ccatctacag gccacacttt 7350

 tactgtattt cttcatactt gaaattcatt ctgctatttt catatcaggg 7400

 tacagactta taagggtgca tgttccttaa aggtgcataa ttattcttat 7450

 tccgtttgct tatattgcta cagaatgctc tgttttggtg ctttgagttc 7500

 tgcagaccca agaagcagtg tggaaattca ctgcctggga cacagtctta 7550

 taagaatgtt ggcaggtgac tttgtatcag atgttgcttc tcttttctct 7600

 gtacacagat tgagagttac cacagtggcc tgtcgggtcc accctgtggg 7650

 tgcagcacag ctctctgaaa gcaagaacct tcctacctat tctaacgttt 7700

 ttgccctcta agaaaaatgg cctcaggtat ggtatagaca tagcaagagg 7750

 ggaagggctg tctcactcta gcaaccatcc ctccattaca cacagaaagc 7800

 cctcttgaag caaaagaaga agaaagaaag aaagcttatc tctaaggcta 7850

 ctgtcttcag aatgctctga gctgaatgct cttgctcctt tcccaagagg 7900

 cagatgaaaa tatagccagt ttatctatac ccttcctatc tgaggaggag 7950

 aatagaaaag tagggtaaat atgtaacgta aaatatgtca ttcaaggacc 8000

 accaaaactt taagtaccct atcattaaaa atctggtttt aaaagtagct 8050

 caagtaaggg atgctttgtg acccagggtt tctgaagtca gatagccatt 8100

 cttacctgcc ccttactctg acttattggg aaagggagaa ctgcagtggt 8150

 gtttctgttg cagtggcaaa ggtaacatgt cagaaaattc agagggttgc 8200

 ataccaataa tcctttggaa actggatgtc ttactgggtg ctagaatgaa 8250

 aatgtaggta tttattgtca gatgatgaag ttcattgttt ttttcaaaat 8300

 tggtgttgaa atatcactgt ccaatgtgtt cacttatgtg aaagctaaat 8350

 tgaatgaggc aaaaagagca aatagtttgt atatttgtaa taccttttgt 8400

 atttcttaca ataaaaatat tggtagcaaa taaaaataat aaaaacaata 8450

 actttaaact gctttctgga gatgaattac tctcctggct attttctttt 8500

 ttactttaat gtaaaatgag tataactgta gtgagtaaaa ttcattaaat 8550

 tccaagtttt agcagaaaaa 8570

<210> 4102
<211> 29
<212> PRT
<213> Homo sapien

<400> 4102
 Pro Tyr Lys Trp Phe Ser Ala Gln Leu Ala Leu Val Thr Arg Gly
   1               5                  10                  15

 His Arg Lys Tyr Leu Leu Glu Ser Leu Ala Thr Cys Ala Phe
                  20                  25

<210> 4103
<211> 2334
<212> DNA
<213> Homo sapien

<400> 4103
 tcttacctat caaaaagaaa catttgtttg agaattccag gcttctgcag 50

 cctccaaaag gtgttcttct ctatgggcct ccaggctgtg gtaaaacgtt 100

 gattgccaag gccacagcca aagaagcagg ctgtcgattt attaaccttc 150

 agccttcgac actgaccgat aagtggtatg gagaatctca gaaattggct 200

 gctgctgtct tctcccttgc cataaagcta caaccatcca tcatctttat 250

 agatgaaata gactcctttc tacgaaaccg ttcaagttct gaccatgaag 300

 ctacagccat gatgaaagct cagtttatga gtctctggga tggattggat 350

 actgatcaca gctgccaggt catagtaatg ggagctacca atcgtcctca 400

 ggaccttgac tcggctataa tgagaagaat gcctacaaga tttcatatca 450

 accagcctgc tttaaaacag agagaagcaa tcctgaaact catcttgaaa 500

 aatgaaaatg tggataggca tgtagacctg ctagaagttg cccaggaaac 550

 tgatgggttt tcaggaagtg acctaaaaga gatgtgtcga gatgctgccc 600

 tcctctgtgt tagagaatat gttaattcta catcagaaga aagccatgac 650

 gaagatgaaa ttcggcctgt tcaacagcag gacctgcatc gggcaattga 700

 aaagatgaag aaatcaaagg atgcagcatt tcagaatgtt ttaacacatg 750

 tttgtttaga ttaagagtaa agatcatttg tacagttcag tgatctagtt 800

 tggtgtgtcc tcttatcagt tagtggaaat agaacggaaa gagtgctctt 850

 taaacaatga gggagctcag tgtttatggt tttatactct gaattctaag 900

 ttattgagat atagttgtta cataggtggt attactgttg gtcaaaaatc 950

 atgaggagga acagttgaat ccagcctgaa cgtgggtgct tgtgtttgac 1000

 cttttcagcc atatattgta cagccttata gaatctaagc tggtcttaaa 1050

 gtcataaatg attcattggg tcattagtga gaaacgggga tgtggttagg 1100

 tgctggttcc tagacatgtg agtatgcgtt tgtgtgtgtg cgtgtatgta 1150

 tgtgtatatt aaatgtatat atccacacat tttatattga cattctgtag 1200

 atatgtttga atatagaaac tttttttacc ccaactactg aatccaggag 1250

 taccaaataa tatatagtaa aactaagatt taaggttgtg tcaaaaaggt 1300

 acagtgattc agccatttcc atttgtcatt tgtttcaacc ttttttaagt 1350

 tgagtgtttt tatttctgca gttattagtt ggatcctcca catcttgcat 1400

 atatacatgg gctcaattat tatgtttgtc aggataatca aatgaaaata 1450

 ctagttcagt gatcagcatt gaatggttgt taggcagcca tgtgctcaac 1500

 actgatttca cctcttgagt ataaactttt taaatttaaa ttggtttaca 1550

 tgaaagtgga ttaaaaggcc tttcaaaaga atgggtttga aaaacctcag 1600

 taccctttaa tacatgtaca tttctttcct ttttttcatt taatgtaaca 1650

 tgtctgttgt aactatgttt cttaaatatt attttaaggt tatgtgttct 1700

 ttaattatgg tcaaatataa tttggtcacc aaaaatgaaa taatagttta 1750

 aaacaagtag ctgttactaa gtgtgctaaa aatactcatt ttataattaa 1800

 ttttagtttt cttagtatat tattataaat tgtgccctaa gtcaggtaca 1850

 aatgtacaca tcaaaatgcc catattgtat ctatctgtag tcgtttaatg 1900

 tgaattatat gtgaattttt ttcaaaattt tactaaccag aattctgtta 1950

 taggcaccta accacgcagc atgaggaaaa cggcacaaca caatcttgag 2000

 gtgccttctg aatcatcaga ttaaattatg cttcatatgt ttttgctttt 2050

 actgtatttc tttaaaaact ctaaatcttt attcatgtgt cactggatta 2100

 atttatctga taatgtgtct cacaagaatc tgttagatcg tttattcttc 2150

 agttgtactt tgaatggtgg ggtggaagtt tcaggtgaac aatggataac 2200

 aaaaagcaag ttatggaaga ttgtgaagag gatggaaaaa ctgaatacaa 2250

 gataccaaaa atgaaaaaaa gtgtcccatt tttaataact atattctatt 2300

 attttataaa tgtgtaataa aggggtccct cttt 2334

<210> 4104
<211> 151
<212> PRT
<213> Homo sapien

<400> 4104
 Met Met Lys Ala Gln Phe Met Ser Leu Trp Asp Gly Leu Asp Thr
   1               5                  10                  15

 Asp His Ser Cys Gln Val Ile Val Met Gly Ala Thr Asn Arg Pro
                  20                  25                  30

 Gln Asp Leu Asp Ser Ala Ile Met Arg Arg Met Pro Thr Arg Phe
                  35                  40                  45

 His Ile Asn Gln Pro Ala Leu Lys Gln Arg Glu Ala Ile Leu Lys
                  50                  55                  60

 Leu Ile Leu Lys Asn Glu Asn Val Asp Arg His Val Asp Leu Leu
                  65                  70                  75

 Glu Val Ala Gln Glu Thr Asp Gly Phe Ser Gly Ser Asp Leu Lys
                  80                  85                  90

 Glu Met Cys Arg Asp Ala Ala Leu Leu Cys Val Arg Glu Tyr Val
                  95                 100                 105

 Asn Ser Thr Ser Glu Glu Ser His Asp Glu Asp Glu Ile Arg Pro
                 110                 115                 120

 Val Gln Gln Gln Asp Leu His Arg Ala Ile Glu Lys Met Lys Lys
                 125                 130                 135

 Ser Lys Asp Ala Ala Phe Gln Asn Val Leu Thr His Val Cys Leu
                 140                 145                 150

 Asp


<210> 4105
<211> 3781
<212> DNA
<213> Homo sapien

<400> 4105
 gggccggctc gcgggcgctg ccagtctcgg gcggcggtgt ccggcgcgcg 50

 ggcggcctgc tgggcgggct gaagggttag cggagcacgg gcaaggcgga 100

 gagtgacgga gtcggcgagc ccccgcggcg acaggttctc tacttaaaag 150

 acaatgacta ctgatgaagg tgccaagaac aatgaagaaa gccccacagc 200

 cactgttgct gagcagggag aggatattac ctccaaaaaa gacaggggag 250

 tattaaagat tgtcaaaaga gtggggaatg gtgaggaaac gccgatgatt 300

 ggagacaaag tttatgtcca ttacaaagga aaattgtcaa atggaaagaa 350

 gtttgattcc agtcatgata gaaatgaacc atttgtcttt agtcttggca 400

 aaggccaagt catcaaggca tgggacattg gggtggctac catgaagaaa 450

 ggagagatat gccatttact gtgcaaacca gaatatgcat atggctcggc 500

 tggcagtctc cctaaaattc cctcgaatgc aactctcttt tttgagattg 550

 agctccttga tttcaaagga gaggatttat ttgaagatgg aggcattatc 600

 cggagaacca aacggaaagg agagggatat tcaaatccaa acgaaggagc 650

 aacagtagaa atccacctgg aaggccgctg tggtggaagg atgtttgact 700

 gcagagatgt ggcattcact gtgggcgaag gagaagacca cgacattcca 750

 attggaattg acaaagctct ggagaaaatg cagcgggaag aacaatgtat 800

 tttatatctt ggaccaagat atggttttgg agaggcaggg aagcctaaat 850

 ttggcattga acctaatgct gagcttatat atgaagttac acttaagagc 900

 ttcgaaaagg ccaaagaatc ctgggagatg gataccaaag aaaaattgga 950

 gcaggctgcc attgtcaaag agaagggaac cgtatacttc aagggaggca 1000

 aatacatgca ggcggtgatt cagtatggga agatagtgtc ctggttagag 1050

 atggaatatg gtttatcaga aaaggaatcg aaagcttctg aatcatttct 1100

 ccttgctgcc tttctgaacc tggccatgtg ctacctgaag cttagagaat 1150

 acaccaaagc tgttgaatgc tgtgacaagg cccttggact ggacagtgcc 1200

 aatgagaaag gcttgtatag gaggggtgaa gcccagctgc tcatgaacga 1250

 gtttgagtca gccaagggtg actttgagaa agtgctggaa gtaaaccccc 1300

 agaataaggc tgcaagactg cagatctcca tgtgccagaa aaaggccaag 1350

 gagcacaacg agcgggaccg caggatatac gccaacatgt tcaagaagtt 1400

 tgcagagcag gatgccaagg aagaggccaa taaagcaatg ggcaagaaga 1450

 cttcagaagg ggtcactaat gaaaaaggaa cagacagtca agcaatggaa 1500

 gaagagaaac ctgagggcca cgtatgacgc cacgccaagg agggaagagt 1550

 cccagtgaac tcggcccctc ctcaatgggc tttcccccaa ctcaggacag 1600

 aacagtgttt aatgtaaagt ttgttatagt ctatgtgatt ctggaagcaa 1650

 atggcaaaac cagtagcttc ccaaaaacag cccccctgct gctgcccgga 1700

 gggttcactg aggggtggca cgggaccact ccaggtggaa caaacagaaa 1750

 tgactgtggt gtggagggag tgagccagca gcttaagtcc agctcatttc 1800

 agtttctatc aaccttcaag tatccaattc agggtccctg gagatcatcc 1850

 taacaatgtg gggctgttag gttttacctt tgaactttca tagcactgca 1900

 gaaacctttt aaaaaaaaat gcttcatgaa tttctccttt cctacagttg 1950

 ggtagggtag gggaaggagg ataagctttt gttttttaaa tgactgaagt 2000

 gctataaatg tagtctgttg catttttaac caacagaacc cacagtagag 2050

 gggtctcatg tctccccagt tccacagcag tgtcacagac gtgaaagcca 2100

 gaacctcaga ggccacttgc ttgctgactt agcctcctcc caaagtcccc 2150

 ctcctcagcc agcctccttg tgagagtggc tttctaccac acacagcctg 2200

 tccctggggg agtaattctg tcattcctaa aacacccttc agcaatgata 2250

 atgagcagat gagagtttct ggattagctt ttcctatttt cgatgaagtt 2300

 ctgagatact gaaatgtgaa aagagcaatc agaattgtgc tttttctccc 2350

 ctcctctatt ccttttaggg aataatattc aatacacagt acttcctccc 2400

 agcattgcta ctgctcagct tcttctttca ttctaatcct tgctattaag 2450

 aatttaagac ttgtgcttac aatatttttg acctggagtg gatctattta 2500

 catagtcatt taggatccat gcagcttttt ttgtcttttt aagattattg 2550

 gctcataagc atatgtatac tggtttatgg aactttattt acactcctct 2600

 atcatgcaaa aaaattttga ctttttagta ctaagcttaa tttttaaaaa 2650

 caaaatctgt agtgttgaca aataaatagt tgctcttcta cactaggggt 2700

 ttcacctgca ggtttgacac gcagttgctc gcttttcctg ccctgtcaag 2750

 cttctctgtt ctggcgtgag ttgtgaaaga gttgaagaca gcttcccatg 2800

 ccggtacaca gccagtagcc taaatctcca gtacttgagc tgaccattga 2850

 actagggcaa gtcttaaatg tgtacatgta gttgaatttc agtccttacg 2900

 ggtaaacaga ttgagcatgg ctctctattc cctcagccta agaaacactc 2950

 atgggaatgc atttggcaac ccaaggaacc atttgcttaa acctggaaca 3000

 tctcaccttt ttaaatccta aaaaacactg gcagttatat tttaaattag 3050

 tttttatttt tatgatggtt ttatcaaaag acttttatta ttagattggg 3100

 acccccttca aacctaaaaa tcaagttatt tccttttata atacttttct 3150

 tccccatgga acaaatggga tcaatttgtg agttttttcc tttaatgata 3200

 actaaaatcc ctctaatttc tcatttatgc ttttgtcttt tttatgaaat 3250

 atttctttta aaagccccag tctcacctac gaaatatgaa gagcaaaagc 3300

 tgattttgct tacttgctaa actgttggga aagctctgta gagcatggtt 3350

 ccagtgaggc caagattgaa atttgatact aaaaaggcca cctagctttt 3400

 tgcagataac aaacaagaaa gctattccaa gactcagatg atgccagctg 3450

 tctcccacgt gtgtattatg gttcaccagg gggaactggc aaaagtgtgt 3500

 gtggggaggg gaagggtgtg tgagtggttc tgagcaaata actacagggt 3550

 gcccattacc actcaagaag acacttcacg tattcttgta tcaaattcaa 3600

 taatcttaaa caatttgtgt agaagtccac agacatcttt caaccacctt 3650

 ttaggctgca tatggattgc caagtcagca tatgaggaat taaagacatt 3700

 gtttttaaaa aaaaaaaatc atttagatgc acttttttgt gtgttcttta 3750

 aataaatcca aaaaaaatgt gaaaaaaaaa a 3781

<210> 4106
<211> 457
<212> PRT
<213> Homo sapien

<400> 4106
 Met Thr Thr Asp Glu Gly Ala Lys Asn Asn Glu Glu Ser Pro Thr
   1               5                  10                  15

 Ala Thr Val Ala Glu Gln Gly Glu Asp Ile Thr Ser Lys Lys Asp
                  20                  25                  30

 Arg Gly Val Leu Lys Ile Val Lys Arg Val Gly Asn Gly Glu Glu
                  35                  40                  45

 Thr Pro Met Ile Gly Asp Lys Val Tyr Val His Tyr Lys Gly Lys
                  50                  55                  60

 Leu Ser Asn Gly Lys Lys Phe Asp Ser Ser His Asp Arg Asn Glu
                  65                  70                  75

 Pro Phe Val Phe Ser Leu Gly Lys Gly Gln Val Ile Lys Ala Trp
                  80                  85                  90

 Asp Ile Gly Val Ala Thr Met Lys Lys Gly Glu Ile Cys His Leu
                  95                 100                 105

 Leu Cys Lys Pro Glu Tyr Ala Tyr Gly Ser Ala Gly Ser Leu Pro
                 110                 115                 120

 Lys Ile Pro Ser Asn Ala Thr Leu Phe Phe Glu Ile Glu Leu Leu
                 125                 130                 135

 Asp Phe Lys Gly Glu Asp Leu Phe Glu Asp Gly Gly Ile Ile Arg
                 140                 145                 150

 Arg Thr Lys Arg Lys Gly Glu Gly Tyr Ser Asn Pro Asn Glu Gly
                 155                 160                 165

 Ala Thr Val Glu Ile His Leu Glu Gly Arg Cys Gly Gly Arg Met
                 170                 175                 180

 Phe Asp Cys Arg Asp Val Ala Phe Thr Val Gly Glu Gly Glu Asp
                 185                 190                 195

 His Asp Ile Pro Ile Gly Ile Asp Lys Ala Leu Glu Lys Met Gln
                 200                 205                 210

 Arg Glu Glu Gln Cys Ile Leu Tyr Leu Gly Pro Arg Tyr Gly Phe
                 215                 220                 225

 Gly Glu Ala Gly Lys Pro Lys Phe Gly Ile Glu Pro Asn Ala Glu
                 230                 235                 240

 Leu Ile Tyr Glu Val Thr Leu Lys Ser Phe Glu Lys Ala Lys Glu
                 245                 250                 255

 Ser Trp Glu Met Asp Thr Lys Glu Lys Leu Glu Gln Ala Ala Ile
                 260                 265                 270

 Val Lys Glu Lys Gly Thr Val Tyr Phe Lys Gly Gly Lys Tyr Met
                 275                 280                 285

 Gln Ala Val Ile Gln Tyr Gly Lys Ile Val Ser Trp Leu Glu Met
                 290                 295                 300

 Glu Tyr Gly Leu Ser Glu Lys Glu Ser Lys Ala Ser Glu Ser Phe
                 305                 310                 315

 Leu Leu Ala Ala Phe Leu Asn Leu Ala Met Cys Tyr Leu Lys Leu
                 320                 325                 330

 Arg Glu Tyr Thr Lys Ala Val Glu Cys Cys Asp Lys Ala Leu Gly
                 335                 340                 345

 Leu Asp Ser Ala Asn Glu Lys Gly Leu Tyr Arg Arg Gly Glu Ala
                 350                 355                 360

 Gln Leu Leu Met Asn Glu Phe Glu Ser Ala Lys Gly Asp Phe Glu
                 365                 370                 375

 Lys Val Leu Glu Val Asn Pro Gln Asn Lys Ala Ala Arg Leu Gln
                 380                 385                 390

 Ile Ser Met Cys Gln Lys Lys Ala Lys Glu His Asn Glu Arg Asp
                 395                 400                 405

 Arg Arg Ile Tyr Ala Asn Met Phe Lys Lys Phe Ala Glu Gln Asp
                 410                 415                 420

 Ala Lys Glu Glu Ala Asn Lys Ala Met Gly Lys Lys Thr Ser Glu
                 425                 430                 435

 Gly Val Thr Asn Glu Lys Gly Thr Asp Ser Gln Ala Met Glu Glu
                 440                 445                 450

 Glu Lys Pro Glu Gly His Val
                 455

<210> 4107
<211> 792
<212> DNA
<213> Homo sapien

<400> 4107
 ggagttgcgc gggctgacgc gccactatgt agcgggtttc gggcgggcca 50

 cgcgtgcggg acaggaaccc aaccccagcc gaccttgagc tccaggagtt 100

 cgtctcttac gtctgcggaa gtgcagctgc ctcagttctt agcgcaggtt 150

 gacaactaca ggcacaagcc attgaagctg gaatgtcctg ttgctggtat 200

 ttcaattgac ttaagccaac tatcccttca gttacaatag gaaagtgcct 250

 ctaataaggc caaatatgcg tactaacttg tagcaaccac gtgtccgtgc 300

 agtgccacag gagctagagc agtgacaatg ctggtggcaa cagggcagtg 350

 tagcaggtgc ttcatgttca ccttttcaac cttttcattt aattgtcaca 400

 actcggaggt ggattctgtt agggacaggc tgccccagga ccactccgcc 450

 cccgctaact caatgcagct gacccttacc ctgaatactc tgcagctgca 500

 ttcctgaacc gttatctagg cgctatagca aggtcaccag acttgctaca 550

 ccgaagccct ctgggtggca cgggggaggt catgagaaac gtggattaca 600

 cccccttgta aattcctatt ttcacaagat aatatattgt aagccggtca 650

 tgagattata tgtggtaaag ttaattgact aacaacccca gggtctctct 700

 cccccatata aacccctcat tttgtaagct cagggctgcc acctccgact 750

 ggtggagaag cctggcaggt taataaactt acttggcctg ac 792

<210> 4108
<211> 5861
<212> DNA
<213> Homo sapien

<400> 4108
 cggcgccgcg cggccgcgct agaatggagg cgcccagcgg cagcgagccc 50

 ggcggcgacg gggccgggga ctgcgcccac ccggaccccc gggcccctgg 100

 cgccgcggcg cccagctccg gccccggccc gtgcgcggcc gcccgggagt 150

 ccgagcgcca gctgcgcctc cgcctctgcg tcctcaacga gatcttgggc 200

 accgagaggg actacgtggg caccttgcgc ttcttgcagt cggcattcct 250

 gcatcgcatc cggcagaacg tggccgactc agtggagaag ggcctcacgg 300

 aggagaatgt caaggtcctg ttctcgaaca tcgaagacat cctggaagtt 350

 cataaggatt tcttggccgc cttggagtat tgtttacacc cggagccgca 400

 gtctcagcat gaacttggga atgttttctt aaaattcaag gacaagttct 450

 gcgtgtacga ggagtattgc agcaaccatg agaaagccct gaggctgctg 500

 gtggagctga acaagatccc taccgtgcgc gccttccttt tgagctgcat 550

 gcttctggga ggccggaaga ccacggacat ccctttggaa ggctacctgt 600

 tgtctccgat ccagaggatc tgcaagtacc cgctcctcct taaggagctg 650

 gccaagagga ctcccggcaa gcacccagac caccccgcgg tccagagtgc 700

 cctgcaggcc atgaagaccg tttgctccaa catcaatgag accaagcggc 750

 agatggagaa gctggaagcc ctggagcagc tgcagtccca catcgaaggc 800

 tgggagggtt ccaacctcac agacatctgc actcagctcc tcctgcaagg 850

 gactttgtta aagatctctg cgggcaacat ccaggaaagg gccttcttcc 900

 tcttcgacaa ccttctcgtc tactgcaagc ggaaatccag ggtcaccggg 950

 agcaagaagt ccaccaagag gaccaaatcc atcaacggct ccctctacat 1000

 cttcaggggt cgaatcaaca ctgaagtcat ggaggtggag aatgtggaag 1050

 atgggacagc ggattaccat agcaatggct ataccgtcac caacggctgg 1100

 aagatccaca acacggccaa gaataagtgg tttgtctgca tggccaagac 1150

 ggcagaggag aagcagaagt ggctggatgc catcatccgc gagcgggagc 1200

 agcgcgagag cctgaagctg ggcatggagc gtgatgccta cgtcatgatt 1250

 gcggagaagg gggagaagct gtaccacatg atgatgaaca agaaggtgaa 1300

 cctcatcaag gaccgccgga gaaagctgag cactgtcccc aagtgctttc 1350

 ttggcaatga gttcgttgcc tggctcctag aaattggtga aatcagcaag 1400

 acggaagaag gagtcaactt gggccaagcc ctgttggaga atggcatcat 1450

 ccaccatgtt tccgacaagc accagttcaa gaatgagcag gtgatgtatc 1500

 gcttccgcta cgacgatggc acctacaagg cccgaagtga gctggaggac 1550

 atcatgtcca agggtgtgag gctttactgc cgtcttcaca gcctctacac 1600

 cccggtgatc aaagaccgtg attaccacct gaagacctac aagtcagtgc 1650

 ttcccgggag caagctggtg gactggctgc tggctcaggg agactgccag 1700

 actcgggagg aggcagtggc gctcggcgtg ggtctgtgca acaatggctt 1750

 catgcaccac gtgctggaga agagcgagtt cagggatgag tcccagtact 1800

 tccgctttca tgctgacgag gagatggagg ggaccagcag caagaacaaa 1850

 cagcttcgca acgacttcaa gctggtggag aacattctgg ccaagcgcct 1900

 gctgatcctg ccccaggagg aggactatgg ctttgacatc gaggagaaga 1950

 acaaggctgt ggtggtgaag tccgtccaga ggggctcgct ggctgaggtg 2000

 gctggcctgc aggtggggag gaagatctac tccatcaatg aggacctggt 2050

 gttcctgcgg ccgttttcag aggtggagtc catcctcaac cagtccttct 2100

 gctcccgccg ccctctgcgc ctcctggtgg ccacgaaggc caaagagatc 2150

 atcaaaatcc ccgaccagcc ggacacactg tgcttccaga ttcgtggagc 2200

 tgccccaccg tacgtctatg ctgtggggag aggctctgag gccatggctg 2250

 cagggctctg tgctggtcag tgcattctga aggtcaatgg cagcaacgtg 2300

 atgaacgatg gtgcccctga ggtcctggag cacttccagg cattccggag 2350

 tcggcgcgaa gaggccctgg gcctgtacca gtggatctac cacacccatg 2400

 aggatgccca ggaagcacga gccagtcagg aggcctccac tgaggacccc 2450

 agtggcgagc aggcccagga ggaagaccag gctgattcag ccttcccact 2500

 gctgtccctg ggtccccggc tgagcctgtg tgaggacagc cccatggtca 2550

 ccctgactgt ggacaacgtg cacctggaac acggcgtggt gtatgagtat 2600

 gtgagcacgg caggcgtcag gtgccatgtg ctggagaaga tcgtggagcc 2650

 ccgcggctgc ttcggcctca ccgccaagat cctcgaggcc tttgctgcca 2700

 atgacagcgt cttcgtggag aactgcaggc ggctcatggc cctgagcagc 2750

 gccatcgtga ccatgcccca ctttgagttc cgcaacatct gtgacaccaa 2800

 gctggagagc attggccaga ggattgcctg ctaccaggag tttgcagccc 2850

 aactgaagag cagggtcagc ccacccttca aacaagcccc cctggagccc 2900

 cacccgctgt gtggcctgga cttctgcccc accaattgcc acatcaacct 2950

 catggaagtg tcctacccca agaccacccc ctcagtgggc aggtccttca 3000

 gcatccgctt tggacgcaaa ccctccctca tcggccttga cccggagcaa 3050

 ggccacctga accccatgtc gtacacccag cactgcatca ccaccatggc 3100

 tgctccctcc tggaagtgct tgcctgctgc agagggtgat ccccaaggcc 3150

 agggtctcca tgatggcagc ttcgggccag ccagtgggac ccttggtcag 3200

 gaagaccggg gcctcagctt cctactcaag caggaggacc gtgagatcca 3250

 ggatgcctac ctgcagctct tcaccaagct ggatgtggcc ctgaaggaga 3300

 tgaagcaata tgtcacccag atcaacaggc tgctgtccac catcacagag 3350

 cccacctcgg gtgggtcctg cgacacatcc ttggctgagg aggcctcctc 3400

 cctgcccctg gtcagtgaag agagcgagat ggacaggagt gaccatgggg 3450

 gcatcaagaa ggtgtgcttc aaggtggccg aggaggacca ggaggactca 3500

 ggccacgaca ccatgagtta tcgcgactcc tacagcgagt gtaacagcaa 3550

 tcgagactcg gtcctgtcct acaccagcgt gagaagtaac agctcctact 3600

 tgggcagcga cgagatgggg tctggagatg agctgccctg tgacatgcgg 3650

 atcccatctg acaagcagga caagcttcat ggctgcctgg agcacctctt 3700

 taaccaggtg gactccatca atgctctcct caaggggcca gtcatgagcc 3750

 gggctttcga agagaccaag catttcccta tgaaccacag cttacaagag 3800

 tttaaacaga aagaagagtg tacaatccgt ggccggagcc tgatccagat 3850

 tagcatccag gaggacccct ggaacctccc caactccatc aagaccctgg 3900

 tggacaacat tcagagatat gtggaagatg ggaagaacca gctgctcctg 3950

 gccttgctga agtgcacaga cacggagctg cagctgcgca gagacgcgat 4000

 cttctgccag gccctggtgg ccgccgtgtg caccttctcc gagcagctgc 4050

 tggcggccct gggctaccgc tacaacaaca atggcgagta cgaggagagc 4100

 agccgcgacg ccagccgcaa gtggctggag caggtggcgg ccacgggcgt 4150

 cctgctgcac tgccagtccc tgctctcgcc agccacagtg aaggaggaac 4200

 ggaccatgct ggaggacatc tgggtgacgc tgtcagagct ggacaatgtc 4250

 accttctcct ttaagcagct ggacgagaac tatgtggcca acaccaacgt 4300

 cttctaccac attgagggca gccggcaggc gctgaaggtc atcttctacc 4350

 tcgacagcta ccacttctcc aagctgccct cccgcctgga gggtggggcc 4400

 agcctgaggc tgcacacagc gctgttcacg aaagtgctgg agaacgtgga 4450

 ggggctgcct tctccaggca gccaggccgc ggaggatttg cagcaggaca 4500

 tcaacgcgca gtccctggag aaagttcagc agtattaccg caaactcagg 4550

 gcattttacc tggagcggtc taacctgccc acggatgcca gcaccacggc 4600

 ggtaaagata gaccagctga tccgccccat caatgccctg gatgagctct 4650

 gccgcctcat gaagtccttt gtccacccaa agcctggtgc tgctgggagt 4700

 gtgggcgccg gcctcatccc catctcctcg gagctctgct accgcctggg 4750

 ggcctgccag atggtcatgt gtggcacagg catgcagagg agcaccctga 4800

 gcgtgtccct ggagcaggcg gccatcttgg cacggagcca cgggttgctg 4850

 cccaagtgca tcatgcaggc cacggacatc atgcggaagc agggcccaag 4900

 ggtggagatt ctggccaaaa acctgcgagt caaggaccag atgccccagg 4950

 gtgctccgcg cctctaccgc ctctgccagc cgccggtgga tggggacctc 5000

 tgaacaccca aatgccccac gctgggccgc ggcctctgga gctgggattt 5050

 gggaggacac agcaggcagc gctggccttc tccagggatg gcccaaggct 5100

 tccgcagccg cccgttccgg gacctgccca gcgtcctccc tgcctccttc 5150

 cgggacaagc ctggccaccc tcgctgtgat gacgagctgg ctgattggcc 5200

 ctgggccggc ccattcttca cacgcctgcc agaagctgga ggggtgctgg 5250

 agacccatag agctgatggg agcagctggt gcctggcctt cggctcctgc 5300

 gtccccagaa cccaagggaa cgtcatggag gccacatggg gccacccggc 5350

 tccctcggga tggctccgcc tgcacttttg aaaccccggt ttccttcaac 5400

 gtccacattc caggtgacca cacgtgtctc ctcctcctca tcttagcttc 5450

 caggttcacc ctaaccctgt actaacctgc ttggtggact tggaaaagac 5500

 ttggctctgt cgggaaagga gagacggggc ctccatcacg cctgttacca 5550

 gaggatcccc gagagccaca ccagctctgg acatcaccgc ccctggaact 5600

 ggggccacca gccctgggca cgagatttgc tctgacttta tttatatggc 5650

 atgaaatctc tggtttattt tgggattttt tgttgttggt gttgtcaaag 5700

 tttgtttttt ctaaagttgt gtgattatat atttgacatt ttacatttca 5750

 aagaaaggta tgttgtctaa caggggacca acagaaggta gtattgacaa 5800

 ctgttcccgc ttctactaaa aaaaaaagag cacaaaagaa aaactaaatt 5850

 attgaaaaat t 5861

<210> 4109
<211> 1659
<212> PRT
<213> Homo sapien

<400> 4109
 Met Glu Ala Pro Ser Gly Ser Glu Pro Gly Gly Asp Gly Ala Gly
   1               5                  10                  15

 Asp Cys Ala His Pro Asp Pro Arg Ala Pro Gly Ala Ala Ala Pro
                  20                  25                  30

 Ser Ser Gly Pro Gly Pro Cys Ala Ala Ala Arg Glu Ser Glu Arg
                  35                  40                  45

 Gln Leu Arg Leu Arg Leu Cys Val Leu Asn Glu Ile Leu Gly Thr
                  50                  55                  60

 Glu Arg Asp Tyr Val Gly Thr Leu Arg Phe Leu Gln Ser Ala Phe
                  65                  70                  75

 Leu His Arg Ile Arg Gln Asn Val Ala Asp Ser Val Glu Lys Gly
                  80                  85                  90

 Leu Thr Glu Glu Asn Val Lys Val Leu Phe Ser Asn Ile Glu Asp
                  95                 100                 105

 Ile Leu Glu Val His Lys Asp Phe Leu Ala Ala Leu Glu Tyr Cys
                 110                 115                 120

 Leu His Pro Glu Pro Gln Ser Gln His Glu Leu Gly Asn Val Phe
                 125                 130                 135

 Leu Lys Phe Lys Asp Lys Phe Cys Val Tyr Glu Glu Tyr Cys Ser
                 140                 145                 150

 Asn His Glu Lys Ala Leu Arg Leu Leu Val Glu Leu Asn Lys Ile
                 155                 160                 165

 Pro Thr Val Arg Ala Phe Leu Leu Ser Cys Met Leu Leu Gly Gly
                 170                 175                 180

 Arg Lys Thr Thr Asp Ile Pro Leu Glu Gly Tyr Leu Leu Ser Pro
                 185                 190                 195

 Ile Gln Arg Ile Cys Lys Tyr Pro Leu Leu Leu Lys Glu Leu Ala
                 200                 205                 210

 Lys Arg Thr Pro Gly Lys His Pro Asp His Pro Ala Val Gln Ser
                 215                 220                 225

 Ala Leu Gln Ala Met Lys Thr Val Cys Ser Asn Ile Asn Glu Thr
                 230                 235                 240

 Lys Arg Gln Met Glu Lys Leu Glu Ala Leu Glu Gln Leu Gln Ser
                 245                 250                 255

 His Ile Glu Gly Trp Glu Gly Ser Asn Leu Thr Asp Ile Cys Thr
                 260                 265                 270

 Gln Leu Leu Leu Gln Gly Thr Leu Leu Lys Ile Ser Ala Gly Asn
                 275                 280                 285

 Ile Gln Glu Arg Ala Phe Phe Leu Phe Asp Asn Leu Leu Val Tyr
                 290                 295                 300

 Cys Lys Arg Lys Ser Arg Val Thr Gly Ser Lys Lys Ser Thr Lys
                 305                 310                 315

 Arg Thr Lys Ser Ile Asn Gly Ser Leu Tyr Ile Phe Arg Gly Arg
                 320                 325                 330

 Ile Asn Thr Glu Val Met Glu Val Glu Asn Val Glu Asp Gly Thr
                 335                 340                 345

 Ala Asp Tyr His Ser Asn Gly Tyr Thr Val Thr Asn Gly Trp Lys
                 350                 355                 360

 Ile His Asn Thr Ala Lys Asn Lys Trp Phe Val Cys Met Ala Lys
                 365                 370                 375

 Thr Ala Glu Glu Lys Gln Lys Trp Leu Asp Ala Ile Ile Arg Glu
                 380                 385                 390

 Arg Glu Gln Arg Glu Ser Leu Lys Leu Gly Met Glu Arg Asp Ala
                 395                 400                 405

 Tyr Val Met Ile Ala Glu Lys Gly Glu Lys Leu Tyr His Met Met
                 410                 415                 420

 Met Asn Lys Lys Val Asn Leu Ile Lys Asp Arg Arg Arg Lys Leu
                 425                 430                 435

 Ser Thr Val Pro Lys Cys Phe Leu Gly Asn Glu Phe Val Ala Trp
                 440                 445                 450

 Leu Leu Glu Ile Gly Glu Ile Ser Lys Thr Glu Glu Gly Val Asn
                 455                 460                 465

 Leu Gly Gln Ala Leu Leu Glu Asn Gly Ile Ile His His Val Ser
                 470                 475                 480

 Asp Lys His Gln Phe Lys Asn Glu Gln Val Met Tyr Arg Phe Arg
                 485                 490                 495

 Tyr Asp Asp Gly Thr Tyr Lys Ala Arg Ser Glu Leu Glu Asp Ile
                 500                 505                 510

 Met Ser Lys Gly Val Arg Leu Tyr Cys Arg Leu His Ser Leu Tyr
                 515                 520                 525

 Thr Pro Val Ile Lys Asp Arg Asp Tyr His Leu Lys Thr Tyr Lys
                 530                 535                 540

 Ser Val Leu Pro Gly Ser Lys Leu Val Asp Trp Leu Leu Ala Gln
                 545                 550                 555

 Gly Asp Cys Gln Thr Arg Glu Glu Ala Val Ala Leu Gly Val Gly
                 560                 565                 570

 Leu Cys Asn Asn Gly Phe Met His His Val Leu Glu Lys Ser Glu
                 575                 580                 585

 Phe Arg Asp Glu Ser Gln Tyr Phe Arg Phe His Ala Asp Glu Glu
                 590                 595                 600

 Met Glu Gly Thr Ser Ser Lys Asn Lys Gln Leu Arg Asn Asp Phe
                 605                 610                 615

 Lys Leu Val Glu Asn Ile Leu Ala Lys Arg Leu Leu Ile Leu Pro
                 620                 625                 630

 Gln Glu Glu Asp Tyr Gly Phe Asp Ile Glu Glu Lys Asn Lys Ala
                 635                 640                 645

 Val Val Val Lys Ser Val Gln Arg Gly Ser Leu Ala Glu Val Ala
                 650                 655                 660

 Gly Leu Gln Val Gly Arg Lys Ile Tyr Ser Ile Asn Glu Asp Leu
                 665                 670                 675

 Val Phe Leu Arg Pro Phe Ser Glu Val Glu Ser Ile Leu Asn Gln
                 680                 685                 690

 Ser Phe Cys Ser Arg Arg Pro Leu Arg Leu Leu Val Ala Thr Lys
                 695                 700                 705

 Ala Lys Glu Ile Ile Lys Ile Pro Asp Gln Pro Asp Thr Leu Cys
                 710                 715                 720

 Phe Gln Ile Arg Gly Ala Ala Pro Pro Tyr Val Tyr Ala Val Gly
                 725                 730                 735

 Arg Gly Ser Glu Ala Met Ala Ala Gly Leu Cys Ala Gly Gln Cys
                 740                 745                 750

 Ile Leu Lys Val Asn Gly Ser Asn Val Met Asn Asp Gly Ala Pro
                 755                 760                 765

 Glu Val Leu Glu His Phe Gln Ala Phe Arg Ser Arg Arg Glu Glu
                 770                 775                 780

 Ala Leu Gly Leu Tyr Gln Trp Ile Tyr His Thr His Glu Asp Ala
                 785                 790                 795

 Gln Glu Ala Arg Ala Ser Gln Glu Ala Ser Thr Glu Asp Pro Ser
                 800                 805                 810

 Gly Glu Gln Ala Gln Glu Glu Asp Gln Ala Asp Ser Ala Phe Pro
                 815                 820                 825

 Leu Leu Ser Leu Gly Pro Arg Leu Ser Leu Cys Glu Asp Ser Pro
                 830                 835                 840

 Met Val Thr Leu Thr Val Asp Asn Val His Leu Glu His Gly Val
                 845                 850                 855

 Val Tyr Glu Tyr Val Ser Thr Ala Gly Val Arg Cys His Val Leu
                 860                 865                 870

 Glu Lys Ile Val Glu Pro Arg Gly Cys Phe Gly Leu Thr Ala Lys
                 875                 880                 885

 Ile Leu Glu Ala Phe Ala Ala Asn Asp Ser Val Phe Val Glu Asn
                 890                 895                 900

 Cys Arg Arg Leu Met Ala Leu Ser Ser Ala Ile Val Thr Met Pro
                 905                 910                 915

 His Phe Glu Phe Arg Asn Ile Cys Asp Thr Lys Leu Glu Ser Ile
                 920                 925                 930

 Gly Gln Arg Ile Ala Cys Tyr Gln Glu Phe Ala Ala Gln Leu Lys
                 935                 940                 945

 Ser Arg Val Ser Pro Pro Phe Lys Gln Ala Pro Leu Glu Pro His
                 950                 955                 960

 Pro Leu Cys Gly Leu Asp Phe Cys Pro Thr Asn Cys His Ile Asn
                 965                 970                 975

 Leu Met Glu Val Ser Tyr Pro Lys Thr Thr Pro Ser Val Gly Arg
                 980                 985                 990

 Ser Phe Ser Ile Arg Phe Gly Arg Lys Pro Ser Leu Ile Gly Leu
                 995                1000                1005

 Asp Pro Glu Gln Gly His Leu Asn Pro Met Ser Tyr Thr Gln His
                1010                1015                1020

 Cys Ile Thr Thr Met Ala Ala Pro Ser Trp Lys Cys Leu Pro Ala
                1025                1030                1035

 Ala Glu Gly Asp Pro Gln Gly Gln Gly Leu His Asp Gly Ser Phe
                1040                1045                1050

 Gly Pro Ala Ser Gly Thr Leu Gly Gln Glu Asp Arg Gly Leu Ser
                1055                1060                1065

 Phe Leu Leu Lys Gln Glu Asp Arg Glu Ile Gln Asp Ala Tyr Leu
                1070                1075                1080

 Gln Leu Phe Thr Lys Leu Asp Val Ala Leu Lys Glu Met Lys Gln
                1085                1090                1095

 Tyr Val Thr Gln Ile Asn Arg Leu Leu Ser Thr Ile Thr Glu Pro
                1100                1105                1110

 Thr Ser Gly Gly Ser Cys Asp Thr Ser Leu Ala Glu Glu Ala Ser
                1115                1120                1125

 Ser Leu Pro Leu Val Ser Glu Glu Ser Glu Met Asp Arg Ser Asp
                1130                1135                1140

 His Gly Gly Ile Lys Lys Val Cys Phe Lys Val Ala Glu Glu Asp
                1145                1150                1155

 Gln Glu Asp Ser Gly His Asp Thr Met Ser Tyr Arg Asp Ser Tyr
                1160                1165                1170

 Ser Glu Cys Asn Ser Asn Arg Asp Ser Val Leu Ser Tyr Thr Ser
                1175                1180                1185

 Val Arg Ser Asn Ser Ser Tyr Leu Gly Ser Asp Glu Met Gly Ser
                1190                1195                1200

 Gly Asp Glu Leu Pro Cys Asp Met Arg Ile Pro Ser Asp Lys Gln
                1205                1210                1215

 Asp Lys Leu His Gly Cys Leu Glu His Leu Phe Asn Gln Val Asp
                1220                1225                1230

 Ser Ile Asn Ala Leu Leu Lys Gly Pro Val Met Ser Arg Ala Phe
                1235                1240                1245

 Glu Glu Thr Lys His Phe Pro Met Asn His Ser Leu Gln Glu Phe
                1250                1255                1260

 Lys Gln Lys Glu Glu Cys Thr Ile Arg Gly Arg Ser Leu Ile Gln
                1265                1270                1275

 Ile Ser Ile Gln Glu Asp Pro Trp Asn Leu Pro Asn Ser Ile Lys
                1280                1285                1290

 Thr Leu Val Asp Asn Ile Gln Arg Tyr Val Glu Asp Gly Lys Asn
                1295                1300                1305

 Gln Leu Leu Leu Ala Leu Leu Lys Cys Thr Asp Thr Glu Leu Gln
                1310                1315                1320

 Leu Arg Arg Asp Ala Ile Phe Cys Gln Ala Leu Val Ala Ala Val
                1325                1330                1335

 Cys Thr Phe Ser Glu Gln Leu Leu Ala Ala Leu Gly Tyr Arg Tyr
                1340                1345                1350

 Asn Asn Asn Gly Glu Tyr Glu Glu Ser Ser Arg Asp Ala Ser Arg
                1355                1360                1365

 Lys Trp Leu Glu Gln Val Ala Ala Thr Gly Val Leu Leu His Cys
                1370                1375                1380

 Gln Ser Leu Leu Ser Pro Ala Thr Val Lys Glu Glu Arg Thr Met
                1385                1390                1395

 Leu Glu Asp Ile Trp Val Thr Leu Ser Glu Leu Asp Asn Val Thr
                1400                1405                1410

 Phe Ser Phe Lys Gln Leu Asp Glu Asn Tyr Val Ala Asn Thr Asn
                1415                1420                1425

 Val Phe Tyr His Ile Glu Gly Ser Arg Gln Ala Leu Lys Val Ile
                1430                1435                1440

 Phe Tyr Leu Asp Ser Tyr His Phe Ser Lys Leu Pro Ser Arg Leu
                1445                1450                1455

 Glu Gly Gly Ala Ser Leu Arg Leu His Thr Ala Leu Phe Thr Lys
                1460                1465                1470

 Val Leu Glu Asn Val Glu Gly Leu Pro Ser Pro Gly Ser Gln Ala
                1475                1480                1485

 Ala Glu Asp Leu Gln Gln Asp Ile Asn Ala Gln Ser Leu Glu Lys
                1490                1495                1500

 Val Gln Gln Tyr Tyr Arg Lys Leu Arg Ala Phe Tyr Leu Glu Arg
                1505                1510                1515

 Ser Asn Leu Pro Thr Asp Ala Ser Thr Thr Ala Val Lys Ile Asp
                1520                1525                1530

 Gln Leu Ile Arg Pro Ile Asn Ala Leu Asp Glu Leu Cys Arg Leu
                1535                1540                1545

 Met Lys Ser Phe Val His Pro Lys Pro Gly Ala Ala Gly Ser Val
                1550                1555                1560

 Gly Ala Gly Leu Ile Pro Ile Ser Ser Glu Leu Cys Tyr Arg Leu
                1565                1570                1575

 Gly Ala Cys Gln Met Val Met Cys Gly Thr Gly Met Gln Arg Ser
                1580                1585                1590

 Thr Leu Ser Val Ser Leu Glu Gln Ala Ala Ile Leu Ala Arg Ser
                1595                1600                1605

 His Gly Leu Leu Pro Lys Cys Ile Met Gln Ala Thr Asp Ile Met
                1610                1615                1620

 Arg Lys Gln Gly Pro Arg Val Glu Ile Leu Ala Lys Asn Leu Arg
                1625                1630                1635

 Val Lys Asp Gln Met Pro Gln Gly Ala Pro Arg Leu Tyr Arg Leu
                1640                1645                1650

 Cys Gln Pro Pro Val Asp Gly Asp Leu
                1655

<210> 4110
<211> 1350
<212> DNA
<213> Homo sapien

<400> 4110
 ggcctcggca gcggtgttct cgcgcttgcg aagcgggctc cggctcggct 50

 cgcggggact gtgcacgagg ttggcgacgc cgccccgccg ggccccagat 100

 caggccgcag agatcgggag ccgcgggagc actaaggcgc aagggccaca 150

 gcagcagccg ggctcagagg gtcccagcta tgccaaaaaa gttgcgctct 200

 ggcttgctgg gctgcttgga gctggtggga ctgtgagcgt cgtctatatc 250

 tttggaaaca acccggtgga cgaaaatggt gccaagattc ctgatgagtt 300

 cgacaatgat ccaattctgg tacagcagtt gcgccggaca tacaaatatt 350

 tcaaagatta tagacagatg atcatcgagc ccaccagccc ttgccttctc 400

 ccagaccctc tgcaggaacc gtactaccag ccaccctaca cgctcgtttt 450

 ggagctcacc ggcgtcctct tgcatcctga gtggtcgctg gccactggct 500

 ggaggtttaa gaagcgccca ggcatcgaga ccttgttcca gcagcttgcc 550

 cctttatatg aaattgtcat ctttacgtca gagactggca tgactgcgtt 600

 tccactcatt gatagtgtgg acccccatgg cttcatctcc taccgcctat 650

 tccgggacgc cacaagatac atggatggac accatgtaaa ggatatttca 700

 tgtctgaatc gggacccagc tcgagtagta gttgtggact gcaagaagga 750

 agccttccgc ctgcagccct ataacggcgt tgccctgcgg ccctgggacg 800

 gcaactctga tgaccgggtc ttgttggatc tgtctgcctt cctcaagacc 850

 attgcactga atggtgtgga ggacgtgcga accgtgctgg agcactatgc 900

 cctggaggat gacccgctgg cggctttcaa acagcggcaa agccggctag 950

 agcaggagga gcagcagcgc ctggccgagc tctccaagtc caacaagcag 1000

 aacctcttcc ttggctccct caccagccgc ttgtggcctc gctccaaaca 1050

 gccctgaact ctgggcctcc tcaaactcag tgcctgggtc cagggcccca 1100

 gtgcttccag accaagactt gggccaccac ttgtccaata aagtacatcc 1150

 cagacgccac acctgctgtg tcccgagagt ctccagatgg gggcatcagg 1200

 gtgaggtccg ggactcttgg gtcatcgtcc cacagtggct gatcggctgc 1250

 caagcacagt gggggtgctt tgttggatca gagcagattt ttcaccctgg 1300

 tctcggaatc taaaaaccct cgctgtgtaa aaaaaaaaaa aaaaaaaaaa 1350

<210> 4111
<211> 351
<212> PRT
<213> Homo sapien

<400> 4111
 Ala Ser Ala Ala Val Phe Ser Arg Leu Arg Ser Gly Leu Arg Leu
   1               5                  10                  15

 Gly Ser Arg Gly Leu Cys Thr Arg Leu Ala Thr Pro Pro Arg Arg
                  20                  25                  30

 Ala Pro Asp Gln Ala Ala Glu Ile Gly Ser Arg Gly Ser Thr Lys
                  35                  40                  45

 Ala Gln Gly Pro Gln Gln Gln Pro Gly Ser Glu Gly Pro Ser Tyr
                  50                  55                  60

 Ala Lys Lys Val Ala Leu Trp Leu Ala Gly Leu Leu Gly Ala Gly
                  65                  70                  75

 Gly Thr Val Ser Val Val Tyr Ile Phe Gly Asn Asn Pro Val Asp
                  80                  85                  90

 Glu Asn Gly Ala Lys Ile Pro Asp Glu Phe Asp Asn Asp Pro Ile
                  95                 100                 105

 Leu Val Gln Gln Leu Arg Arg Thr Tyr Lys Tyr Phe Lys Asp Tyr
                 110                 115                 120

 Arg Gln Met Ile Ile Glu Pro Thr Ser Pro Cys Leu Leu Pro Asp
                 125                 130                 135

 Pro Leu Gln Glu Pro Tyr Tyr Gln Pro Pro Tyr Thr Leu Val Leu
                 140                 145                 150

 Glu Leu Thr Gly Val Leu Leu His Pro Glu Trp Ser Leu Ala Thr
                 155                 160                 165

 Gly Trp Arg Phe Lys Lys Arg Pro Gly Ile Glu Thr Leu Phe Gln
                 170                 175                 180

 Gln Leu Ala Pro Leu Tyr Glu Ile Val Ile Phe Thr Ser Glu Thr
                 185                 190                 195

 Gly Met Thr Ala Phe Pro Leu Ile Asp Ser Val Asp Pro His Gly
                 200                 205                 210

 Phe Ile Ser Tyr Arg Leu Phe Arg Asp Ala Thr Arg Tyr Met Asp
                 215                 220                 225

 Gly His His Val Lys Asp Ile Ser Cys Leu Asn Arg Asp Pro Ala
                 230                 235                 240

 Arg Val Val Val Val Asp Cys Lys Lys Glu Ala Phe Arg Leu Gln
                 245                 250                 255

 Pro Tyr Asn Gly Val Ala Leu Arg Pro Trp Asp Gly Asn Ser Asp
                 260                 265                 270

 Asp Arg Val Leu Leu Asp Leu Ser Ala Phe Leu Lys Thr Ile Ala
                 275                 280                 285

 Leu Asn Gly Val Glu Asp Val Arg Thr Val Leu Glu His Tyr Ala
                 290                 295                 300

 Leu Glu Asp Asp Pro Leu Ala Ala Phe Lys Gln Arg Gln Ser Arg
                 305                 310                 315

 Leu Glu Gln Glu Glu Gln Gln Arg Leu Ala Glu Leu Ser Lys Ser
                 320                 325                 330

 Asn Lys Gln Asn Leu Phe Leu Gly Ser Leu Thr Ser Arg Leu Trp
                 335                 340                 345

 Pro Arg Ser Lys Gln Pro
                 350

<210> 4112
<211> 959
<212> DNA
<213> Homo sapien

<400> 4112
 gctttcgccg cctgggagcc gtccggcgca gcagtttcta ggtccccact 50

 gtccccgccg tcccgcccct tcgcgtcccg ggaaccggct ggcttccgag 100

 ccgcactcgc cgatcctcca ggcatgcccc gctacgagct ggctttaatc 150

 ctgaaagcca tgcagcggcc agagactgct gctactttga aacgtacgat 200

 agaggccctg atggacagag gagcaatagt gagggacttg gaaaacctgg 250

 gtgaacgagc gcttccttat aggatctctg cccacagtca gcagcacaac 300

 agaggcgggt atttcttggt ggatttttat gcacccaccg cagctgttga 350

 aagcatggtg gagcacttgt ctcgagatat agatgtgatt agagggaata 400

 ttgtcaaaca ccctctgacc caggaactaa aagaatgtga agggattgtc 450

 ccagtcccac tcgcagaaaa attatattcc acaaagaaga ggaagaagtg 500

 agaagattcg ccagatttta gccttatatg taattccttc acatttgggc 550

 agcatggacg agaaggaaga atttgcaagt ttggccttta tataagcatg 600

 tgttgcaggt gctgtttgat ttttctaagg tatttttagc ccttgatccc 650

 ctttgcttgc gagaggtggg gaactgctca ctgacagctt ctctgtaacc 700

 tgcagtacca gtggatcatt cttgattttg ttttcattag tgtcatttct 750

 ttgtcattga ggacttttcc ccttacaaca gtaacaccat tttttgaaga 800

 gcaaaactta taatacctcc tgggattgtg agctagtcat tcagcctgtg 850

 taaccatgtg gaaataaaaa ttgacgacca atgtattata tggacaactt 900

 ttgctttgag taataaactt gattgtaggg aaaaaaaaaa aaaaaaaaaa 950

 aaaaaaaaa 959

<210> 4113
<211> 125
<212> PRT
<213> Homo sapien

<400> 4113
 Met Pro Arg Tyr Glu Leu Ala Leu Ile Leu Lys Ala Met Gln Arg
   1               5                  10                  15

 Pro Glu Thr Ala Ala Thr Leu Lys Arg Thr Ile Glu Ala Leu Met
                  20                  25                  30

 Asp Arg Gly Ala Ile Val Arg Asp Leu Glu Asn Leu Gly Glu Arg
                  35                  40                  45

 Ala Leu Pro Tyr Arg Ile Ser Ala His Ser Gln Gln His Asn Arg
                  50                  55                  60

 Gly Gly Tyr Phe Leu Val Asp Phe Tyr Ala Pro Thr Ala Ala Val
                  65                  70                  75

 Glu Ser Met Val Glu His Leu Ser Arg Asp Ile Asp Val Ile Arg
                  80                  85                  90

 Gly Asn Ile Val Lys His Pro Leu Thr Gln Glu Leu Lys Glu Cys
                  95                 100                 105

 Glu Gly Ile Val Pro Val Pro Leu Ala Glu Lys Leu Tyr Ser Thr
                 110                 115                 120

 Lys Lys Arg Lys Lys
                 125

<210> 4114
<211> 4708
<212> DNA
<213> Homo sapien

<400> 4114
 ggcacgaggg ccgttttcag aggtggagtc catcctcaac cagtccttct 50

 gctcccgccg ccctctgcgc ctcctggtgg ccacgaaggc caaagagatc 100

 atcaaaatcc ccgaccagcc ggacacactg tgcttccaga ttcgtggagc 150

 tgccccaccg tacgtctatg ctgtggggag aggctctgag gccatggctg 200

 cagggctctg tgctggtcag tgcattctga aggtcaatgg cagcaacgtg 250

 atgaacgatg gtgcccctga ggtcctggag cacttccagg cattccggag 300

 tcggcgcgaa gaggccctgg gcctgtacca gtggatctac cacacccatg 350

 aggatgccca ggaagcacga gccagtcagg aggcctccac tgaggacccc 400

 agtggcgagc aggcccagga ggaagaccag gctgattcag ccttcccact 450

 gctgtccctg ggtccccggc tgagcctgtg tgaggacagc cccatggtca 500

 ccctgactgt ggacaacgtg cacctggaac acggcgtggt gtatgagtat 550

 gtgagcacgg caggcgtcag gtgccatgtg ctggagaaga tcgtggagcc 600

 ccgcggctgc ttcggcctca ccgccaagat cctcgaggcc tttgctgcca 650

 atgacagcgt cttcgtggag aactgcaggc ggctcatggc cctgagcagc 700

 gccatcgtga ccatgcccca ctttgagttc cgcaacatct gtgacaccaa 750

 gctggagagc attggccaga ggattgcctg ctaccaggag tttgcagccc 800

 aactgaagag cagggtcagc ccacccttca aacaagcccc cctggagccc 850

 cacccgctgt gtggcctgga cttctgcccc accaattgcc acatcaacct 900

 catggaagtg tcctacccca agaccacccc ctcagtgggc aggtccttca 950

 gcatccgctt tggacgcaaa ccctccctca tcggccttga cccggagcaa 1000

 ggccacctga accccatgtc gtacacccag cactgcatca ccaccatggc 1050

 tgctccctcc tggaagtgct tgcctgctgc agagggtgat ccccaaggcc 1100

 agggtctcca tgatggcagc ttcgggccag ccagtgggac ccttggtcag 1150

 gaagaccggg gcctcagctt cctactcaag caggaggacc gtgagatcca 1200

 ggatgcctac ctgcagctct tcaccaagct ggatgtggcc ctgaaggaga 1250

 tgaagcaata tgtcacccag atcaacaggc tgctgtccac catcacagag 1300

 cccacctcgg gtgggtcctg cgacgcatcc ttggctgagg aggcctcctc 1350

 cctgcccctg gtcagtgaag agagcgagat ggacaggagt gaccatgggg 1400

 gcatcaagaa ggtgtgcttc aaggtggccg aggaggacca ggaggactca 1450

 ggccacgaca ccatgagtta tcgcgactcc tacagcgagt gtaacagcaa 1500

 tcgagactcg gtcctgtcct acaccagcgt gagaagtaac agctcctact 1550

 tgggcagcga cgagatgggg tctggagatg agctgccctg tgacatgcgg 1600

 atcccatctg acaagcagga caagcttcat ggctgcctgg agcacctctt 1650

 taaccaggtg gactccatca atgctctcct caaggggcca gtcatgagcc 1700

 gggctttcga agagaccaag catttcccta tgaaccacag cttacaagag 1750

 tttaaacaga aagaagagtg tacaatccgt ggccggagcc tgatccagat 1800

 tagcatccag gaggacccct ggaacctccc caactccatc aagaccctgg 1850

 tggacaacat tcagagatat gtggaagatg ggaagaacca gctgctcctg 1900

 gccttgctga agtgcacaga cacggagctg cagctgcgca gagacgcgat 1950

 cttctgccag gccctggtgg ccgccgtgtg caccttctcc gagcagctgc 2000

 tggcggccct gggctaccgc tacaacaaca atggcgagta cgaggagagc 2050

 agccgcgacg ccagccgcaa gtggctggag caggtggcgg ccacgggcgt 2100

 cctgctgcac tgccagtccc tgctctcgcc agccacagtg aaggaggaac 2150

 ggaccatgct ggaggacatc tgggtgacgc tgtcagagct ggacaatgtc 2200

 accttctcct ttaagcagct ggacgagaac tatgtggcca acaccaacgt 2250

 cttctaccac attgagggca gccggcaggc gctgaaggtc atcttctacc 2300

 tcgacagcta ccacttctcc aagctgccct cccgcctgga gggtggggcc 2350

 agcctgaggc tgcacacagc gctgttcacg aaaggtgagc ttcaggcctg 2400

 gggcagggag gaccacgggg gccgggccaa ggccaccaag cacaccggct 2450

 cccaaccgcc tgcccgcccc cgacatctcc cctcccagtg ctggagaacg 2500

 tggaggggct gccttctcca ggcagccagg ccgcggagga tttgcagcag 2550

 gacatcaacg cgcagtccct ggagaaagtt cagcagtatt accgcaaact 2600

 cagggcattt tacctggagc ggtctaacct gcccacggat gccagcacca 2650

 cggcggtaaa gatagaccag ctgatccgcc ccatcaatgc cctggatgag 2700

 ctctgccgcc tcatgaagtc ctttgtccac ccaaagcctg gtgctgctgg 2750

 gagtgtgggc gccggcctca tccccatctc ctcggagctc tgctaccgcc 2800

 tgggggcctg ccagatggtc atgtgtggca caggcatgca gaggagcacc 2850

 ctgagcgtgt ccctggagca ggcggccatc ttggcacgga gccacgggtt 2900

 gctgcccaag tgcatcatgc aggccacgga catcatgcgg aagcagggcc 2950

 caagggtgga gattctggcc aaaaacctgc gagtcaagga ccagatgccc 3000

 cagggtgctc cgcgcctcta ccgcctctgc cagccgccgg tggatgggga 3050

 cctctgaaca cccaaatgcc ccacgctggg ccgcggcctc tggagctggg 3100

 atttgggagg acacagcagg cagcgctggc cttctccagg gatggcccaa 3150

 ggcttccgca gccgcccgtt ccgggacctg cccagcgtcc tccctgcctc 3200

 cttccgggac aagcctggcc accctcgctg tgatgacgag ctggctgatt 3250

 ggccctgggc cggcccattc ttcacacgcc tgccagaagc tggaggggtg 3300

 ctggagaccc atagagctga tgggagcagc tggtgcctgg ccttcggctc 3350

 ctgcgtcccc agaacccaag ggaacgtcat ggaggccaca tggggccacc 3400

 cggctccctc gggatggctc cgcctgcact tttgaaaccc cggtttcctt 3450

 caacgtccac attccaggtg accacacgtg tctcctcctc ctcatcttag 3500

 cttccaggtt caccctaacc ctgtactaac ctgcttggtg gacttggaaa 3550

 agacttggct ctgtcgggaa aggagagacg gggcctccat cacgcctgtt 3600

 accagaggat ccccgagagc cacaccagct ctggacatca ccgcccctgg 3650

 aactggggcc accagccctg ggcacgagat ttgctctgac tttatttata 3700

 tggcatgaaa tctctggttt attttgggat tttttgttgt tggtgttgtc 3750

 aaagtttgtt ttttctaaag ttgtgtgatt atatatttga cattttacat 3800

 ttcaaagaaa ggtatgttgt ctaacagggg accaacagaa ggtagtattg 3850

 acaactgttc ctgcttctac taaaaaaaaa agagcacaaa agaaaaacta 3900

 aattattgaa aaattaaaaa atgtcattgt ttcctgtttg ttaatattag 3950

 ggttgtaagg tgtcgttttg aggtatcgac tgtgattcct tcccccaccc 4000

 tccattctcc agcggttggc cggtgttaga actcgctctc tttgagtgac 4050

 tggctacaag ggcctgagag gtggccagcc agggttggag ctggagggga 4100

 tggagcccca cctgaggtgc cgtgtcacac gggttagagg gtcactggga 4150

 aacaccgggc ggtggcttct gtgatttatt ttcttgatgg taacttctca 4200

 gagcagggcg attgggacat caccagccag agcacaggaa gccaccctgc 4250

 ctgctgggga ggagggaccc acacaagccc cctcggcagt ttgtcccccc 4300

 agcttcggta tgccttcagg gaaaggtcac agctggggag gaagcggggg 4350

 gacgcctgtc acccctggca ggtggtgagt tcaggtgggg gctccctgct 4400

 gcccccaggc ctgggagctt gaagccctcc cggcatctgg catccgagcc 4450

 tcccgccctc cagggtgcgc ttccctctct tgccgcagca tacacgaggg 4500

 caggcagtgg ccttgtcact gtatcttgca tcagagacaa aggaggaccc 4550

 gctttagccc tgctgcggga aatgggggag ggcccagggc cagcgcattg 4600

 tgcactggtt tactttaaaa tgtacagatt cttctcgtta aattcttgat 4650

 agatttttta ttattattaa aagtcagttt ataatacaaa aaaaaaaaaa 4700

 aaaaaaaa 4708

<210> 4115
<211> 885
<212> PRT
<213> Homo sapien

<400> 4115
 Ala Arg Gly Pro Phe Ser Glu Val Glu Ser Ile Leu Asn Gln Ser
   1               5                  10                  15

 Phe Cys Ser Arg Arg Pro Leu Arg Leu Leu Val Ala Thr Lys Ala
                  20                  25                  30

 Lys Glu Ile Ile Lys Ile Pro Asp Gln Pro Asp Thr Leu Cys Phe
                  35                  40                  45

 Gln Ile Arg Gly Ala Ala Pro Pro Tyr Val Tyr Ala Val Gly Arg
                  50                  55                  60

 Gly Ser Glu Ala Met Ala Ala Gly Leu Cys Ala Gly Gln Cys Ile
                  65                  70                  75

 Leu Lys Val Asn Gly Ser Asn Val Met Asn Asp Gly Ala Pro Glu
                  80                  85                  90

 Val Leu Glu His Phe Gln Ala Phe Arg Ser Arg Arg Glu Glu Ala
                  95                 100                 105

 Leu Gly Leu Tyr Gln Trp Ile Tyr His Thr His Glu Asp Ala Gln
                 110                 115                 120

 Glu Ala Arg Ala Ser Gln Glu Ala Ser Thr Glu Asp Pro Ser Gly
                 125                 130                 135

 Glu Gln Ala Gln Glu Glu Asp Gln Ala Asp Ser Ala Phe Pro Leu
                 140                 145                 150

 Leu Ser Leu Gly Pro Arg Leu Ser Leu Cys Glu Asp Ser Pro Met
                 155                 160                 165

 Val Thr Leu Thr Val Asp Asn Val His Leu Glu His Gly Val Val
                 170                 175                 180

 Tyr Glu Tyr Val Ser Thr Ala Gly Val Arg Cys His Val Leu Glu
                 185                 190                 195

 Lys Ile Val Glu Pro Arg Gly Cys Phe Gly Leu Thr Ala Lys Ile
                 200                 205                 210

 Leu Glu Ala Phe Ala Ala Asn Asp Ser Val Phe Val Glu Asn Cys
                 215                 220                 225

 Arg Arg Leu Met Ala Leu Ser Ser Ala Ile Val Thr Met Pro His
                 230                 235                 240

 Phe Glu Phe Arg Asn Ile Cys Asp Thr Lys Leu Glu Ser Ile Gly
                 245                 250                 255

 Gln Arg Ile Ala Cys Tyr Gln Glu Phe Ala Ala Gln Leu Lys Ser
                 260                 265                 270

 Arg Val Ser Pro Pro Phe Lys Gln Ala Pro Leu Glu Pro His Pro
                 275                 280                 285

 Leu Cys Gly Leu Asp Phe Cys Pro Thr Asn Cys His Ile Asn Leu
                 290                 295                 300

 Met Glu Val Ser Tyr Pro Lys Thr Thr Pro Ser Val Gly Arg Ser
                 305                 310                 315

 Phe Ser Ile Arg Phe Gly Arg Lys Pro Ser Leu Ile Gly Leu Asp
                 320                 325                 330

 Pro Glu Gln Gly His Leu Asn Pro Met Ser Tyr Thr Gln His Cys
                 335                 340                 345

 Ile Thr Thr Met Ala Ala Pro Ser Trp Lys Cys Leu Pro Ala Ala
                 350                 355                 360

 Glu Gly Asp Pro Gln Gly Gln Gly Leu His Asp Gly Ser Phe Gly
                 365                 370                 375

 Pro Ala Ser Gly Thr Leu Gly Gln Glu Asp Arg Gly Leu Ser Phe
                 380                 385                 390

 Leu Leu Lys Gln Glu Asp Arg Glu Ile Gln Asp Ala Tyr Leu Gln
                 395                 400                 405

 Leu Phe Thr Lys Leu Asp Val Ala Leu Lys Glu Met Lys Gln Tyr
                 410                 415                 420

 Val Thr Gln Ile Asn Arg Leu Leu Ser Thr Ile Thr Glu Pro Thr
                 425                 430                 435

 Ser Gly Gly Ser Cys Asp Ala Ser Leu Ala Glu Glu Ala Ser Ser
                 440                 445                 450

 Leu Pro Leu Val Ser Glu Glu Ser Glu Met Asp Arg Ser Asp His
                 455                 460                 465

 Gly Gly Ile Lys Lys Val Cys Phe Lys Val Ala Glu Glu Asp Gln
                 470                 475                 480

 Glu Asp Ser Gly His Asp Thr Met Ser Tyr Arg Asp Ser Tyr Ser
                 485                 490                 495

 Glu Cys Asn Ser Asn Arg Asp Ser Val Leu Ser Tyr Thr Ser Val
                 500                 505                 510

 Arg Ser Asn Ser Ser Tyr Leu Gly Ser Asp Glu Met Gly Ser Gly
                 515                 520                 525

 Asp Glu Leu Pro Cys Asp Met Arg Ile Pro Ser Asp Lys Gln Asp
                 530                 535                 540

 Lys Leu His Gly Cys Leu Glu His Leu Phe Asn Gln Val Asp Ser
                 545                 550                 555

 Ile Asn Ala Leu Leu Lys Gly Pro Val Met Ser Arg Ala Phe Glu
                 560                 565                 570

 Glu Thr Lys His Phe Pro Met Asn His Ser Leu Gln Glu Phe Lys
                 575                 580                 585

 Gln Lys Glu Glu Cys Thr Ile Arg Gly Arg Ser Leu Ile Gln Ile
                 590                 595                 600

 Ser Ile Gln Glu Asp Pro Trp Asn Leu Pro Asn Ser Ile Lys Thr
                 605                 610                 615

 Leu Val Asp Asn Ile Gln Arg Tyr Val Glu Asp Gly Lys Asn Gln
                 620                 625                 630

 Leu Leu Leu Ala Leu Leu Lys Cys Thr Asp Thr Glu Leu Gln Leu
                 635                 640                 645

 Arg Arg Asp Ala Ile Phe Cys Gln Ala Leu Val Ala Ala Val Cys
                 650                 655                 660

 Thr Phe Ser Glu Gln Leu Leu Ala Ala Leu Gly Tyr Arg Tyr Asn
                 665                 670                 675

 Asn Asn Gly Glu Tyr Glu Glu Ser Ser Arg Asp Ala Ser Arg Lys
                 680                 685                 690

 Trp Leu Glu Gln Val Ala Ala Thr Gly Val Leu Leu His Cys Gln
                 695                 700                 705

 Ser Leu Leu Ser Pro Ala Thr Val Lys Glu Glu Arg Thr Met Leu
                 710                 715                 720

 Glu Asp Ile Trp Val Thr Leu Ser Glu Leu Asp Asn Val Thr Phe
                 725                 730                 735

 Ser Phe Lys Gln Leu Asp Glu Asn Tyr Val Ala Asn Thr Asn Val
                 740                 745                 750

 Phe Tyr His Ile Glu Gly Ser Arg Gln Ala Leu Lys Val Ile Phe
                 755                 760                 765

 Tyr Leu Asp Ser Tyr His Phe Ser Lys Leu Pro Ser Arg Leu Glu
                 770                 775                 780

 Gly Gly Ala Ser Leu Arg Leu His Thr Ala Leu Phe Thr Lys Gly
                 785                 790                 795

 Glu Leu Gln Ala Trp Gly Arg Glu Asp His Gly Gly Arg Ala Lys
                 800                 805                 810

 Ala Thr Lys His Thr Gly Ser Gln Pro Pro Ala Arg Pro Arg His
                 815                 820                 825

 Leu Pro Ser Gln Cys Trp Arg Thr Trp Arg Gly Cys Leu Leu Gln
                 830                 835                 840

 Ala Ala Arg Pro Arg Arg Ile Cys Ser Arg Thr Ser Thr Arg Ser
                 845                 850                 855

 Pro Trp Arg Lys Phe Ser Ser Ile Thr Ala Asn Ser Gly His Phe
                 860                 865                 870

 Thr Trp Ser Gly Leu Thr Cys Pro Arg Met Pro Ala Pro Arg Arg
                 875                 880                 885

<210> 4116
<211> 6160
<212> DNA
<213> Homo sapien

<400> 4116
 ctcgcgagga gagcggagca ggcgcgcggc ccaggcggag gagcgccgac 50

 tctggagcag ccggagctgg aagaggagga ggaggagagg cggcggggaa 100

 ggaggaggag ggggagagtc gctcccgccg ggcgagcatg gggcgcctgg 150

 cctcgaggcc gctgctgctg gcgctcctgt cgttggctct ttgccgaggg 200

 cgtgtggtga gagtccccac agcgaccctg gttcgagtgg tgggcactga 250

 gctggtcatc ccctgcaacg tcagtgacta tgatggcccc agcgagcaaa 300

 actttgactg gagcttctca tctttgggga gcagctttgt ggagcttgca 350

 agcacctggg aggtggggtt cccagcccag ctgtaccagg agcggctgca 400

 gaggggcgag atcctgttaa ggcggactgc caacgacgcc gtggagctcc 450

 acataaagaa cgtccagcct tcagaccaag gccactacaa atgttcaacc 500

 cccagcacag atgccactgt ccagggaaac tatgaggaca cagtgcaggt 550

 taaagtgctg gccgactccc tgcacgtggg ccccagcgcg cggcccccgc 600

 cgagcctgag cctgcgggag ggggagccct tcgagctgcg ctgcactgcc 650

 gcctccgcct cgccgctgca cacgcacctg gcgctgctgt gggaggtgca 700

 ccgcggcccg gccaggcgga gcgtcctcgc cctgacccac gagggcaggt 750

 tccacccggg cctggggtac gagcagcgct accacagtgg ggacgtgcgc 800

 ctcgacaccg tgggcagcga cgcctaccgc ctctcagtgt cccgggctct 850

 gtctgccgac cagggctcct acaggtgtat cgtcagcgag tggatcgccg 900

 agcagggcaa ctggcaggaa atccaagaaa aggccgtgga agttgccacc 950

 gtggtgatcc agccatcagt tctgcgagca gctgtgccca agaatgtgtc 1000

 tgtggctgaa ggaaaggaac tggacctgac ctgtaacatc acaacagacc 1050

 gagccgatga cgtccggccc gaggtgacgt ggtccttcag caggatgcct 1100

 gacagcaccc tacctggctc ccgcgtgttg gcgcggcttg accgtgattc 1150

 cctggtgcac agctcgcctc atgttgcttt gagtcatgtg gatgcacgct 1200

 cctaccattt actggttcgg gatgttagca aagaaaactc tggctactat 1250

 tactgccacg tgtccctgtg ggcacccgga cacaacagga gctggcacaa 1300

 agtggcagag gccgtgtctt ccccagctgg tgtgggtgtg acctggctag 1350

 aaccagacta ccaggtgtac ctgaatgctt ccaaggtccc cgggtttgcg 1400

 gatgacccca cagagctggc atgccgggtg gtggacacga agagtgggga 1450

 ggcgaatgtc cgattcacgg tttcgtggta ctacaggatg aaccggcgca 1500

 gcgacaatgt ggtgaccagc gagctgcttg cagtcatgga cggggactgg 1550

 acgctaaaat atggagagag gagcaagcag cgggcccagg atggagactt 1600

 tattttttct aaggaacata cagacacgtt caatttccgg atccaaagga 1650

 ctacagagga agacagaggc aattattact gtgttgtgtc tgcctggacc 1700

 aaacagcgga acaacagctg ggtgaaaagc aaggatgtct tctccaagcc 1750

 tgttaacata ttttgggcat tagaagattc cgtgcttgtg gtgaaggcga 1800

 ggcagccaaa gcctttcttt gctgccggaa atacatttga gatgacttgc 1850

 aaagtatctt ccaagaatat taagtcgcca cgctactctg ttctcatcat 1900

 ggctgagaag cctgtcggcg acctctccag tcccaatgaa acgaagtaca 1950

 tcatctctct ggaccaggat tctgtggtga agctggagaa ttggacagat 2000

 gcatcacggg tggatggcgt tgttttagaa aaagtgcagg aggatgagtt 2050

 ccgctatcga atgtaccaga ctcaggtctc agacgcaggg ctgtaccgct 2100

 gcatggtgac agcctggtct cctgtcaggg gcagcctttg gcgagaagca 2150

 gcaaccagtc tctccaatcc tattgagata gacttccaaa cctcaggtcc 2200

 tatatttaat gcttctgtgc attcagacac accatcagta attcggggag 2250

 atctgatcaa attgttctgt atcatcactg tcgagggagc agcactggat 2300

 ccagatgaca tggcctttga tgtgtcctgg tttgcggtgc actcttttgg 2350

 cctggacaag gctcctgtgc tcctgtcttc cctggatcgg aagggcatcg 2400

 tgaccacctc ccggagggac tggaagagcg acctcagcct ggagcgcgtg 2450

 agtgtgctgg aattcttgct gcaagtgcat ggctccgagg accaggactt 2500

 tggcaactac tactgttccg tgactccatg ggtgaagtca ccaacaggtt 2550

 cctggcagaa ggaggcagag atccactcca agcccgtttt tataactgtg 2600

 aagatggatg tgctgaacgc cttcaagtat cccttgctga tcggcgtcgg 2650

 tctgtccacg gtcatcgggc tcctgtcctg tctcatcggg tactgcagct 2700

 cccactggtg ttgtaagaag gaggttcagg agacacggcg cgagcgccgc 2750

 aggctcatgt cgatggagat ggactaggct ggcccgggag gggagtgaca 2800

 gagggacgtt ctaggagcaa ttggggcaag aagaggacag tgatatttta 2850

 aaacaaagtg tgttacacta aaaaccagtc ctctctaatc tcaggtggga 2900

 cttggcgctc tctcttttct gcatgtcaag ttctgagcgc ggacatgttt 2950

 accagcacac ggctcttctt cccacggcac tttctgatgt aacaatcgag 3000

 tgtgtgtttt cccaactgca gctttttaat ggttaacctt catctaattt 3050

 tttttctccc actggtttat agatcctctg acttgtgtgt gtttatagct 3100

 tttgtttcgc ggggttgtgg tgaggaaggg gtgatggcat gcggagttct 3150

 ttatcttcag tgagaatgtg cctgcccgcc tgagagccag cttccgcgtt 3200

 ggaggcacgt gttcagagag ctgctgagcg ccaccctcta cccggctgac 3250

 agacaacaca gacctgtgcc gaaggctaat ttgtggcttt tacgacccta 3300

 ccccaccccc tgttttcagg ggtttagact acatttgaaa tccaaacttg 3350

 gagtatataa cttcttattg agcccaactg cttttttttt tttttttttt 3400

 gcttctctgc cccttttcca tttcttttgt atttgttttc tgtgagagca 3450

 ctgaaatggc agccctggaa tctacaattt ggctctccac tgagcacctt 3500

 atcttgccac cttagcctta agaatgaata tgaagaaaaa tacacagcca 3550

 cctctgtcca gggcagtaag aagggctgca aggaagggga ggatggggac 3600

 aaggaaagga tcagatacct gctccagtag ttgtgaggcc actgtgtctc 3650

 aggggactcc aggaggagca gaagagggat cccacgaagt tattcttacg 3700

 cagctggggc caggagggtc agagtggtgc caggtgcaag ttaggctaaa 3750

 gaagccacca ctattcctct ctcttgccca ttgtgggggg caaaggcatt 3800

 ggtcaccaag agtcttgcag ggggacccac agatatgcca tgtccttcac 3850

 acgtgcttgg gctccttaac ctgaaggcaa attgctactt gcaagactga 3900

 ctgacttcaa ggaatcagaa attacctaga agcaccatgt tttttctatg 3950

 accttttcag tccttcaggt cattttaagg tccactgcag ggggttagtg 4000

 agaaagggta tactttgtgg tatgttttgc tttcctaata gggacatgaa 4050

 ggaaacccag caatttgctg ttatgtgaat ggcctgtaga gcagagtcaa 4100

 gagcggtgtg ctttgcccga ctgctcccat caggaatagg agagtagaca 4150

 gagatcttcc acatcccagg cttctgctgc tgctttaaaa gctctgtcct 4200

 tggagcctcc cgctccctga agtgtctcgc cccctgcaca gcactggcct 4250

 ttcggaagca tcccagtagg gttttctgag gctcgctggt gactcatgcc 4300

 ctaattgcaa tcctctgctt ttatcttgac tttgaaggat ctaacactgc 4350

 tctctcttcc aaaggggaaa aaaagattca tttgttttga gcaataaact 4400

 aatacaaaat gatggccatt catgtgcagc tctttgtcac catgggccgg 4450

 atgagttgtg ctcctcctgg ctcaccattt ccccctgctc ccccacagcc 4500

 ggttctgcac ttatcaccga gtcgcccctg gaagcagatt cccattgagt 4550

 tttccccacc aaggggacca tgcacatggt agaaacatta gattctgcat 4600

 tgacagtagc ctttccttgg cccgggcctg tggtgggaag acgggcaaca 4650

 agtatacccc accagggcct gagtgactag aggaagagga cgaggccttg 4700

 ttggcactag atttgggtat tttctgcatg tcataacata tcctaactgc 4750

 tatttcagaa gaggcagctt gtaggtgatt gtacaagtga gaattaaaga 4800

 gagaacagat atttaaacag gtgctgtatt agtaacagcc agtgcccttt 4850

 cagcccttgc atctattaaa aggagattca ggattttatt ggcacaggcc 4900

 cttcttagta ggaagaaagg gtgcttagct ttggacctga ccgggtgtgt 4950

 gtaaaaccat ggactgagtc acagcagaca ctcgatggtg gtaaatgtga 5000

 tgggtgctta cacactgtac cttttccttt catactgatg ctgcagttca 5050

 gggctggagt tgttaaggca ttgacctcca cccacctgcc ccatgtccac 5100

 tgggctgccc aagctgcatg tcacctgagg gctggcagga aggggcgaga 5150

 aatcccaggg cattgtacca aggacctagt tccttctagg gatataaatt 5200

 tccaggaatg tgtattttta atgtggtgag atgcactctt ttgttgtacc 5250

 aaatagggct ccccacccca cccctgcgac aagtgctctt ctagaacagg 5300

 ttcctaccag cagcactggt gtgaatgaaa gagagaccca gccgcgtctc 5350

 acacaggtgg aattgcactt cttaacaaaa aggaacttta taaaagtttg 5400

 ggattttttt tcctaatcat aaaaatagcc ccagaaagag cctaagctat 5450

 gttcagatag aagcctcgaa attcctgtaa attgtttact ttatgatgtt 5500

 tacatacacg tttcactttg aaaaaaaatg caaatcgact ttttaacaac 5550

 tgttgagatg tttcatggga cagtagaact ctgactcacc aactgggcta 5600

 aattttaatt taaaaatgta tttatttgag tgtctttccc cccctcaccc 5650

 tcaccatctg aggggctccc tgagatcttg gtagaggagg cccctcctgc 5700

 ccagaccttc gtttgtttcc ccggtggccc ttgcttcttg ctttgcagac 5750

 tgcctgcagc catgattttg tcactgacat ctgtgagcca aagactgagc 5800

 ctttttggca ggaataataa gcaatactac acaacttgct actttcagaa 5850

 aacttttttt tagcttcacc gatgacaaca gaggaagaag ggaactggga 5900

 tttgggtaag ttctcctcca ctgtttgacc aaattctcag tgataaatat 5950

 gtgtgcagat ccctagaaga gaaaacgctg actttctttt taagtgtggc 6000

 acataaggat ctgcagaatt ttccgtagac aaagaaagga tcttgtgtat 6050

 ttttgtccat atccaatgtt atatgaacta attgtattgt tttatactgt 6100

 gaccacaaat attatgcaat gcaccatttg ttttttattt cattaaagga 6150

 agtttaattt 6160

<210> 4117
<211> 924
<212> PRT
<213> Homo sapien

<400> 4117
 Arg Glu Glu Ser Gly Ala Gly Ala Arg Pro Arg Arg Arg Ser Ala
   1               5                  10                  15

 Asp Ser Gly Ala Ala Gly Ala Gly Arg Gly Gly Gly Gly Glu Ala
                  20                  25                  30

 Ala Gly Lys Glu Glu Glu Gly Glu Ser Arg Ser Arg Arg Ala Ser
                  35                  40                  45

 Met Gly Arg Leu Ala Ser Arg Pro Leu Leu Leu Ala Leu Leu Ser
                  50                  55                  60

 Leu Ala Leu Cys Arg Gly Arg Val Val Arg Val Pro Thr Ala Thr
                  65                  70                  75

 Leu Val Arg Val Val Gly Thr Glu Leu Val Ile Pro Cys Asn Val
                  80                  85                  90

 Ser Asp Tyr Asp Gly Pro Ser Glu Gln Asn Phe Asp Trp Ser Phe
                  95                 100                 105

 Ser Ser Leu Gly Ser Ser Phe Val Glu Leu Ala Ser Thr Trp Glu
                 110                 115                 120

 Val Gly Phe Pro Ala Gln Leu Tyr Gln Glu Arg Leu Gln Arg Gly
                 125                 130                 135

 Glu Ile Leu Leu Arg Arg Thr Ala Asn Asp Ala Val Glu Leu His
                 140                 145                 150

 Ile Lys Asn Val Gln Pro Ser Asp Gln Gly His Tyr Lys Cys Ser
                 155                 160                 165

 Thr Pro Ser Thr Asp Ala Thr Val Gln Gly Asn Tyr Glu Asp Thr
                 170                 175                 180

 Val Gln Val Lys Val Leu Ala Asp Ser Leu His Val Gly Pro Ser
                 185                 190                 195

 Ala Arg Pro Pro Pro Ser Leu Ser Leu Arg Glu Gly Glu Pro Phe
                 200                 205                 210

 Glu Leu Arg Cys Thr Ala Ala Ser Ala Ser Pro Leu His Thr His
                 215                 220                 225

 Leu Ala Leu Leu Trp Glu Val His Arg Gly Pro Ala Arg Arg Ser
                 230                 235                 240

 Val Leu Ala Leu Thr His Glu Gly Arg Phe His Pro Gly Leu Gly
                 245                 250                 255

 Tyr Glu Gln Arg Tyr His Ser Gly Asp Val Arg Leu Asp Thr Val
                 260                 265                 270

 Gly Ser Asp Ala Tyr Arg Leu Ser Val Ser Arg Ala Leu Ser Ala
                 275                 280                 285

 Asp Gln Gly Ser Tyr Arg Cys Ile Val Ser Glu Trp Ile Ala Glu
                 290                 295                 300

 Gln Gly Asn Trp Gln Glu Ile Gln Glu Lys Ala Val Glu Val Ala
                 305                 310                 315

 Thr Val Val Ile Gln Pro Ser Val Leu Arg Ala Ala Val Pro Lys
                 320                 325                 330

 Asn Val Ser Val Ala Glu Gly Lys Glu Leu Asp Leu Thr Cys Asn
                 335                 340                 345

 Ile Thr Thr Asp Arg Ala Asp Asp Val Arg Pro Glu Val Thr Trp
                 350                 355                 360

 Ser Phe Ser Arg Met Pro Asp Ser Thr Leu Pro Gly Ser Arg Val
                 365                 370                 375

 Leu Ala Arg Leu Asp Arg Asp Ser Leu Val His Ser Ser Pro His
                 380                 385                 390

 Val Ala Leu Ser His Val Asp Ala Arg Ser Tyr His Leu Leu Val
                 395                 400                 405

 Arg Asp Val Ser Lys Glu Asn Ser Gly Tyr Tyr Tyr Cys His Val
                 410                 415                 420

 Ser Leu Trp Ala Pro Gly His Asn Arg Ser Trp His Lys Val Ala
                 425                 430                 435

 Glu Ala Val Ser Ser Pro Ala Gly Val Gly Val Thr Trp Leu Glu
                 440                 445                 450

 Pro Asp Tyr Gln Val Tyr Leu Asn Ala Ser Lys Val Pro Gly Phe
                 455                 460                 465

 Ala Asp Asp Pro Thr Glu Leu Ala Cys Arg Val Val Asp Thr Lys
                 470                 475                 480

 Ser Gly Glu Ala Asn Val Arg Phe Thr Val Ser Trp Tyr Tyr Arg
                 485                 490                 495

 Met Asn Arg Arg Ser Asp Asn Val Val Thr Ser Glu Leu Leu Ala
                 500                 505                 510

 Val Met Asp Gly Asp Trp Thr Leu Lys Tyr Gly Glu Arg Ser Lys
                 515                 520                 525

 Gln Arg Ala Gln Asp Gly Asp Phe Ile Phe Ser Lys Glu His Thr
                 530                 535                 540

 Asp Thr Phe Asn Phe Arg Ile Gln Arg Thr Thr Glu Glu Asp Arg
                 545                 550                 555

 Gly Asn Tyr Tyr Cys Val Val Ser Ala Trp Thr Lys Gln Arg Asn
                 560                 565                 570

 Asn Ser Trp Val Lys Ser Lys Asp Val Phe Ser Lys Pro Val Asn
                 575                 580                 585

 Ile Phe Trp Ala Leu Glu Asp Ser Val Leu Val Val Lys Ala Arg
                 590                 595                 600

 Gln Pro Lys Pro Phe Phe Ala Ala Gly Asn Thr Phe Glu Met Thr
                 605                 610                 615

 Cys Lys Val Ser Ser Lys Asn Ile Lys Ser Pro Arg Tyr Ser Val
                 620                 625                 630

 Leu Ile Met Ala Glu Lys Pro Val Gly Asp Leu Ser Ser Pro Asn
                 635                 640                 645

 Glu Thr Lys Tyr Ile Ile Ser Leu Asp Gln Asp Ser Val Val Lys
                 650                 655                 660

 Leu Glu Asn Trp Thr Asp Ala Ser Arg Val Asp Gly Val Val Leu
                 665                 670                 675

 Glu Lys Val Gln Glu Asp Glu Phe Arg Tyr Arg Met Tyr Gln Thr
                 680                 685                 690

 Gln Val Ser Asp Ala Gly Leu Tyr Arg Cys Met Val Thr Ala Trp
                 695                 700                 705

 Ser Pro Val Arg Gly Ser Leu Trp Arg Glu Ala Ala Thr Ser Leu
                 710                 715                 720

 Ser Asn Pro Ile Glu Ile Asp Phe Gln Thr Ser Gly Pro Ile Phe
                 725                 730                 735

 Asn Ala Ser Val His Ser Asp Thr Pro Ser Val Ile Arg Gly Asp
                 740                 745                 750

 Leu Ile Lys Leu Phe Cys Ile Ile Thr Val Glu Gly Ala Ala Leu
                 755                 760                 765

 Asp Pro Asp Asp Met Ala Phe Asp Val Ser Trp Phe Ala Val His
                 770                 775                 780

 Ser Phe Gly Leu Asp Lys Ala Pro Val Leu Leu Ser Ser Leu Asp
                 785                 790                 795

 Arg Lys Gly Ile Val Thr Thr Ser Arg Arg Asp Trp Lys Ser Asp
                 800                 805                 810

 Leu Ser Leu Glu Arg Val Ser Val Leu Glu Phe Leu Leu Gln Val
                 815                 820                 825

 His Gly Ser Glu Asp Gln Asp Phe Gly Asn Tyr Tyr Cys Ser Val
                 830                 835                 840

 Thr Pro Trp Val Lys Ser Pro Thr Gly Ser Trp Gln Lys Glu Ala
                 845                 850                 855

 Glu Ile His Ser Lys Pro Val Phe Ile Thr Val Lys Met Asp Val
                 860                 865                 870

 Leu Asn Ala Phe Lys Tyr Pro Leu Leu Ile Gly Val Gly Leu Ser
                 875                 880                 885

 Thr Val Ile Gly Leu Leu Ser Cys Leu Ile Gly Tyr Cys Ser Ser
                 890                 895                 900

 His Trp Cys Cys Lys Lys Glu Val Gln Glu Thr Arg Arg Glu Arg
                 905                 910                 915

 Arg Arg Leu Met Ser Met Glu Met Asp
                 920

<210> 4118
<211> 3272
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2167-2368
<223> Unknown base

<400> 4118
 ggttggtgcg agcttccagc ttggccgcag ttggttcgta gttcggctct 50

 ggggtctttt gtgtccgggt ctggcttggc tttgtgtccg cgagtttttg 100

 ttccgctccg cagcgctctt cccgggcagg agccgtgagg ctcggaggcg 150

 gcagcgcggt ccccggccag gagcaagcgc gccggcgtga gcggcggcgg 200

 caaaggctgt ggggaggggg cttcgcagat ccccgagatg ccggagttcc 250

 tggaagaccc ctcggtcctg acaaaagaca agttgaagag tgagttggtc 300

 gccaacaatg tgacgctgcc ggccggggag cagcgcaaag acgtgtacgt 350

 ccagctctac ctgcagcacc tcacggctcg caaccggccg ccgctccccg 400

 ccggcaccaa cagcaagggg cccccggact tctccagtga cgaagagcgc 450

 gagcccaccc cggtcctcgg ctctggggcc gccgccgcgg gccggagccg 500

 agcagccgtc ggcaggaaag ccacaaaaaa aactgataaa cccagacaag 550

 aagataaaga tgatctagat gtaacagagc tcactaatga agatcttttg 600

 gatcagcttg tgaaatacgg agtgaatcct ggtcctattg tgggaacaac 650

 caggaagcta tatgagaaaa agcttttgaa actgagggaa caaggaacag 700

 aatcaagatc ttctactcct ctgccaacaa tttcttcttc agcagaaaat 750

 acaaggcaga atggaagtaa tgattctgac agatacagtg acaatgaaga 800

 agactctaaa atagagctca agcttgagaa gagagaacca ctaaagggca 850

 gagcaaagac tccagtaaca ctcaagcaaa gaagagttga gcacaatcag 900

 gtgggagaaa aaacagagga aagaagagta gaaagggata ttcttaagga 950

 aatgttcccc tatgaagcat ctacaccaac aggaattagt gctagttgcc 1000

 gcagaccaat caaaggggct gcaggccggc cattagaact cagtgatttc 1050

 aggatggagg agtctttttc atctaaatat gttcctaagt atgttccctt 1100

 ggcagatgtc aagtcagaaa agacaaaaaa gggacgctcc attcccgtat 1150

 ggataaaaat tttgctgttt gttgttgtgg cagttttttt gtttttggtc 1200

 tatcaagcta tggaaaccaa ccaagtaaat cccttctcta attttcttca 1250

 tgttgaccct agaaaatcca actgaatggt atctctttgg cacgttcaac 1300

 ttggtctcct attttcaata actgttgaaa aacatttgtg tacacttgtt 1350

 gactccaaga actaaaaata atgtgatttc gcctcaataa atgtagtatt 1400

 tcattgaaaa gcaaacaaaa tatatataaa tggacttcat taaaatgttt 1450

 ttgaactttg gactagtagg agatcacttt gtgccatatg aataatcttt 1500

 tttagctctg gaactttttg taggctttat ttttttaatg tgggcatctt 1550

 atttcatttt tgaaaaaatg tatatgtttt ttgtgtattt gggaaacgaa 1600

 gggtgaaaca tggtagtata atgtgaagct acacatttaa atacttagaa 1650

 ttcttacaga aaagatttta agaattattc tctgctgaat aaaaactgca 1700

 aatatgtgaa acataatgaa attcagtaag aggaaaagta acttggttgt 1750

 actttttgta actgcaacaa agtttgatgg tgtttatgag gaaaagtaca 1800

 gcaataatct cttctgtaac ctttattaat agtaatgttg ttgtagccct 1850

 atcatactca ctttttaaga cacagtatca tgaaagtcct atttcagtaa 1900

 gacccattta catacagtag atttttagca gagatctttt agtgtaacat 1950

 acatatttta gagaattgtt ggctagctgt acatgttttg aaaagctgtt 2000

 tagctagcta taaggctata attggaaatt tgtatttttt atttacagca 2050

 aaacatttat tcagtcatcc agtttgctac caaaatatgt tttagataag 2100

 tgtgtgtatg tttgtttaga agttagaaat tgtaaacact ggtcttatgt 2150

 ttcatttgga ttcattnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2350

 nnnnnnnnnn nnnnnnnnct cttgaaatgg ttatctttgt ggatgatttt 2400

 tttttttaag ctgaaactta cctcatgaat aacttgatta aagtagtagg 2450

 tgattaaaat ttcaatagaa tcaaatgaga caaaaatttt aaactgactc 2500

 atttgagttt caactttaca gtcattgacc ataaagcaca ctaaaaatgt 2550

 aagttatttt taaatacatc tgaaataaaa atacttacta aaaaggaaga 2600

 agccgaagat gtatatttag accagcacac aattttgatt tcaattagcc 2650

 ttattctaat atttagcttt tagatctttc atacacattt tcacgtactt 2700

 tgcaattgag accagaaaga cttgtaggtc tttctgcaga atgagtgggt 2750

 ccttgcaaag tgagtgggaa acttactcct agatcagaaa tgtttgcctc 2800

 tctgagtaaa atgtttcttt cagatgagcc atagaggggg caccttttac 2850

 tcaacttttc tttgttttga aactttgttt cccatactgt tttcagcctt 2900

 ttgtttataa ttagaaattg tgagaagctt catttagtgt ttaaaaatgt 2950

 ggggagataa atcagactta acatgtatgt aagatcaatt cacttaaaag 3000

 tatggtccaa atagcaaaaa taggaccagg tgaaacatgt agtcattttt 3050

 taaaaacatg tacttggtct tttgtgtgtg tctgttttat tccattagaa 3100

 taaatgtgtc cttgatgtaa atgcaaagca tttcttcctg attaaattgt 3150

 agatgtagac tttacaatat aattcaataa taaaaagtaa ttaacctcta 3200

 gttttgtcgt tgcaataaat ggttttcaga tagcacaaac tgtgatttct 3250

 ggataacatt tcttatgaaa aa 3272

<210> 4119
<211> 424
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2167-2368
<223> Unknown amino acid

<400> 4119
 Val Gly Ala Ser Phe Gln Leu Gly Arg Ser Trp Phe Val Val Arg
   1               5                  10                  15

 Leu Trp Gly Leu Leu Cys Pro Gly Leu Ala Trp Leu Cys Val Arg
                  20                  25                  30

 Glu Phe Leu Phe Arg Ser Ala Ala Leu Phe Pro Gly Arg Ser Arg
                  35                  40                  45

 Glu Ala Arg Arg Arg Gln Arg Gly Pro Arg Pro Gly Ala Ser Ala
                  50                  55                  60

 Pro Gly Val Ser Gly Gly Gly Lys Gly Cys Gly Glu Gly Ala Ser
                  65                  70                  75

 Gln Ile Pro Glu Met Pro Glu Phe Leu Glu Asp Pro Ser Val Leu
                  80                  85                  90

 Thr Lys Asp Lys Leu Lys Ser Glu Leu Val Ala Asn Asn Val Thr
                  95                 100                 105

 Leu Pro Ala Gly Glu Gln Arg Lys Asp Val Tyr Val Gln Leu Tyr
                 110                 115                 120

 Leu Gln His Leu Thr Ala Arg Asn Arg Pro Pro Leu Pro Ala Gly
                 125                 130                 135

 Thr Asn Ser Lys Gly Pro Pro Asp Phe Ser Ser Asp Glu Glu Arg
                 140                 145                 150

 Glu Pro Thr Pro Val Leu Gly Ser Gly Ala Ala Ala Ala Gly Arg
                 155                 160                 165

 Ser Arg Ala Ala Val Gly Arg Lys Ala Thr Lys Lys Thr Asp Lys
                 170                 175                 180

 Pro Arg Gln Glu Asp Lys Asp Asp Leu Asp Val Thr Glu Leu Thr
                 185                 190                 195

 Asn Glu Asp Leu Leu Asp Gln Leu Val Lys Tyr Gly Val Asn Pro
                 200                 205                 210

 Gly Pro Ile Val Gly Thr Thr Arg Lys Leu Tyr Glu Lys Lys Leu
                 215                 220                 225

 Leu Lys Leu Arg Glu Gln Gly Thr Glu Ser Arg Ser Ser Thr Pro
                 230                 235                 240

 Leu Pro Thr Ile Ser Ser Ser Ala Glu Asn Thr Arg Gln Asn Gly
                 245                 250                 255

 Ser Asn Asp Ser Asp Arg Tyr Ser Asp Asn Glu Glu Asp Ser Lys
                 260                 265                 270

 Ile Glu Leu Lys Leu Glu Lys Arg Glu Pro Leu Lys Gly Arg Ala
                 275                 280                 285

 Lys Thr Pro Val Thr Leu Lys Gln Arg Arg Val Glu His Asn Gln
                 290                 295                 300

 Val Gly Glu Lys Thr Glu Glu Arg Arg Val Glu Arg Asp Ile Leu
                 305                 310                 315

 Lys Glu Met Phe Pro Tyr Glu Ala Ser Thr Pro Thr Gly Ile Ser
                 320                 325                 330

 Ala Ser Cys Arg Arg Pro Ile Lys Gly Ala Ala Gly Arg Pro Leu
                 335                 340                 345

 Glu Leu Ser Asp Phe Arg Met Glu Glu Ser Phe Ser Ser Lys Tyr
                 350                 355                 360

 Val Pro Lys Tyr Val Pro Leu Ala Asp Val Lys Ser Glu Lys Thr
                 365                 370                 375

 Lys Lys Gly Arg Ser Ile Pro Val Trp Ile Lys Ile Leu Leu Phe
                 380                 385                 390

 Val Val Val Ala Val Phe Leu Phe Leu Val Tyr Gln Ala Met Glu
                 395                 400                 405

 Thr Asn Gln Val Asn Pro Phe Ser Asn Phe Leu His Val Asp Pro
                 410                 415                 420

 Arg Lys Ser Asn


<210> 4120
<211> 833
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 533-668, 737
<223> Unknown base

<400> 4120
 atgggatggg gtaggaagga atgttaatat gagagaaatt ttaaaatgta 50

 taaaaaagta aaaggttgta tgtttgctca gtttgaaata aagtgaatac 100

 cgtgcctggc cagaaaatct ggattcttat tcctagttct tcatttctgt 150

 cacatgcact tagttgacat tacatctaca tatattagct ttttcctaca 200

 tgagccatct atttacttag taaccagtgt tcttaatgaa gtatttagtc 250

 ttgggtttct tgtaaaattt ctctgcattc cttagacagt gtactataca 300

 tgaaatattc ttgttgacct agtaatttat attattccat ttaattctta 350

 aacctatggc ctttttattg agcacactct taaatcatta tttggcttgt 400

 aaacattcat ctgaattgtg gctacaatcc tctttaaata atctaggaaa 450

 aaagaaagat aaagcttaca ttttcacagt tttggctctt aaacacattc 500

 cacaaatgcc attaagaatt tattttgttt tannnnnnnn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 650

 nnnnnnnnnn nnnnnnnntt tgttttagag tcatttaatg tgtttttatg 700

 cacaataata gtgggaggtt gttttgttgc gtttgtntgt ttgttttggt 750

 ttgtttgttt tgctttccat gtgggaaaag ttaacattgg aactgtttct 800

 agtaaaagat ttttttcagg ctgggcacgg tgg 833

<210> 4121
<211> 110
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 60-105
<223> unknown amino acid

<220>
<221> Unsure
<222> 533-668, 737
<223> Unknown amino acid

<400> 4121
 Met Ala Phe Leu Leu Ser Thr Leu Leu Asn His Tyr Leu Ala Cys
   1               5                  10                  15

 Lys His Ser Ser Glu Leu Trp Leu Gln Ser Ser Leu Asn Asn Leu
                  20                  25                  30

 Gly Lys Lys Lys Asp Lys Ala Tyr Ile Phe Thr Val Leu Ala Leu
                  35                  40                  45

 Lys His Ile Pro Gln Met Pro Leu Arg Ile Tyr Phe Val Leu Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Cys Phe Arg Val Ile
                 110

<210> 4122
<211> 1683
<212> DNA
<213> Homo sapien

<400> 4122
 agaaacggca gtggcagcag cgtccggagc agccgcagcc ttctggaagc 50

 tccaggcggt ctttctgccg agcctcggtc ccggccccca tcctccccgc 100

 cccatcggtt gttgtctggg cggatttaaa cagtcaagta aaatcaagct 150

 gggtaatcat ggcagaaggt ggatttgatc cctgtgaatg tgtttgctct 200

 catgaacatg caatgagaag actgatcaat ctgttacggc agtcccagtc 250

 ctactgcaca gacacagagt gtcttcagga attaccggga ccctctggtg 300

 ataatggcat cagtgttaca atgatcttgg tagcctggat ggttattgca 350

 ttgatcttgt tcttactgag acctcctaat ctaagaggat ccagcctacc 400

 tggaaagcca accagtcctc ataatggaca agatccacca gctcctcctg 450

 tggactaact ttgtgatatg ggaagtgaaa atagttaaca ccttgcacga 500

 ccaaacgaac gaagatgacc agagtactct taaccccatt agaactgttt 550

 ttccttttgt atctgcaata tgggatggta ttgttttcat gagcttctag 600

 aaatttcact tgcaagttta tttttgcttc ctgtgttact gccattccta 650

 tttacagtat atttgagtga atgattatat ttttaaaaag ttacatgggg 700

 cttttttggt tgtcctaaac ttacaaacat tccactcatt ctgtttgtaa 750

 ctgtgattat aatttttgtg ataatttctg gcctgattga aggaaatttg 800

 agaggtctgc atttatatat tttaaataga tttgataggt ttttaaattg 850

 ctttttttca taaggtattt ataaagttat ttggggttgt ctgggattgt 900

 gtgaaagaaa attagaacca cgctgtattt acatttacct tggtagttta 950

 tttgtggatg gcagttttct gtagttttgg ggactgtggt agctcttgga 1000

 ttgttttgca aattacagct gaaatctgtg tcatggatta aactggctta 1050

 tgtggctaga ataggaagag agaaaaaatg aaatggttgt ttactaattt 1100

 tatactccca ttaaaaatct ctaatgttaa gaaaacctta aataaacatg 1150

 attgatcaat atggcagatg atttacagtc cattatatga catttgtaag 1200

 ccactcaaca ctagccttac aaggttcatg aaaggaggaa aacattaatt 1250

 ctttctgcct ttgctgatat aatccacata gtaataattt aagctataat 1300

 ttatttttaa aatgagtgcc tcttgggaag cttcttttct gttctaacag 1350

 ttccctgtta aaatgaaaat cttaggccag tgcagtggct cacacctgta 1400

 atctcagcac tttgggaggc tgaggtgggt ggatcacttg aggtcaggag 1450

 ttcgagacca gcctggccaa catggtgaaa ccctgtctct actaaaaata 1500

 cagaaaaatt agccagggtt ggtgcatgtg cctgtaatcc cagctactca 1550

 ggaggccaaa gcaggagaat tgcttgaacc cgggaggtgg aggttgcagt 1600

 gaaccaagat cgcaccactg cattccagcc taagcaatag agcgagactc 1650

 cctcccaaaa aaaaaaaaaa aaaaaaaaaa aaa 1683

<210> 4123
<211> 99
<212> PRT
<213> Homo sapien

<400> 4123
 Met Ala Glu Gly Gly Phe Asp Pro Cys Glu Cys Val Cys Ser His
   1               5                  10                  15

 Glu His Ala Met Arg Arg Leu Ile Asn Leu Leu Arg Gln Ser Gln
                  20                  25                  30

 Ser Tyr Cys Thr Asp Thr Glu Cys Leu Gln Glu Leu Pro Gly Pro
                  35                  40                  45

 Ser Gly Asp Asn Gly Ile Ser Val Thr Met Ile Leu Val Ala Trp
                  50                  55                  60

 Met Val Ile Ala Leu Ile Leu Phe Leu Leu Arg Pro Pro Asn Leu
                  65                  70                  75

 Arg Gly Ser Ser Leu Pro Gly Lys Pro Thr Ser Pro His Asn Gly
                  80                  85                  90

 Gln Asp Pro Pro Ala Pro Pro Val Asp
                  95

<210> 4124
<211> 688
<212> DNA
<213> Homo sapien

<400> 4124
 cagagcgcgg cggctggaag ctgctaagtc agagccgcga tgttccggat 50

 tgagggcctc gcgccgaagc tggacccgga ggagatgaaa cggaagatgc 100

 gcgaggatgt gatctcctcc atacggaact ttctcatcta cgtggccctc 150

 ctgcgagtca ctccatttat cttaaagaaa ttggacagca tatgaagaca 200

 ggacatcaca tatgaatgca cgatatgaag agcctggtta cagtttcgac 250

 tcctctctgc aagtgaatag gcccagaaag gtgtaagaga ctctttgaat 300

 ggacataaaa ttctgcttgt taagaacaag tttggctctg gtaactgacc 350

 ttcaaagcta aaatataaaa ctatttggga agtatgaaac gatgtctcgt 400

 gatctggtgt acccttatcc ctgtgacgtt tggcctctga caatactggt 450

 ataattgtaa ataatgtcaa actccgtttt ctagcaagta ttaagggagc 500

 tgtgtctgaa atggcactgt cttgtcagtc atttctgttt acctttttct 550

 tctgcccaga gtgtatttgt gaagagtctc ttatattatg ttttgtggaa 600

 atcagcacac aaccacaatg acatttaagc acaggatcat tattagtcta 650

 tgtttttaat aaacatatca attaaaaaaa aaaaaaaa 688

<210> 4125
<211> 51
<212> PRT
<213> Homo sapien

<400> 4125
 Met Phe Arg Ile Glu Gly Leu Ala Pro Lys Leu Asp Pro Glu Glu
   1               5                  10                  15

 Met Lys Arg Lys Met Arg Glu Asp Val Ile Ser Ser Ile Arg Asn
                  20                  25                  30

 Phe Leu Ile Tyr Val Ala Leu Leu Arg Val Thr Pro Phe Ile Leu
                  35                  40                  45

 Lys Lys Leu Asp Ser Ile
                  50

<210> 4126
<211> 2440
<212> DNA
<213> Homo sapien

<400> 4126
 gctcgggcgc ggggcgttct tggtgcgccg ggccgtggtg agtccgggct 50

 cccgtggccg cgtgctggga ggagactgga gcccggttag gaagaatgga 100

 gttggcgact cgctaccaga tccctaaaga agtggctgac atctttaacg 150

 cccccagtga tgatgaagag tttgttggct tccgagatga tgttcccatg 200

 gaaaccctct cgtcagagga gagctgcgat agttttgact cactagagtc 250

 agggaaacag caggatgtgc gctttcattc caaatacttc acagaagagc 300

 taagaagaat ttttatagag gacactgact cagagactga ggattttgca 350

 ggatttacgc agagtgatct gaatggaaag actaacccag aagtaatggt 400

 cgtggagtca gatttgagtg atgatggcaa agcatctttg gtgagcgagg 450

 aagaggaaga tgaagaagaa gataaggcta cccctagaag aagcaggtct 500

 agaagaagta gtattggtct tcgagtagcc tttcagttcc ccaccaagaa 550

 gctggccaac aaaccagata aaaacagttc ttccgagcag ttgttttcta 600

 gcgcacgctt acagaatgag aaaaaaacaa ttcttgaaag aaagaaagac 650

 tgtagacagg tgatacaaag ggaagattct acctctgagt ctgaggatga 700

 ctctcgggat gagagccagg agagttcaga tgctttgctg aaaaggacca 750

 tgaacatcaa ggagaacaaa gccatgcttg cccagttatt ggcggaattg 800

 aactcgatgc cagatttctt cccagtacga accccaacct cagcttctag 850

 gaagaagaca gtgaggcggg ccttccggag ggacagatca cgcggcgtat 900

 gaacccaacc cggagtgcgc ggcctcctga gaagtttgct ctagagaact 950

 tcactgtctc agccgctaaa tttgcggaag agttttacag cttccgaaga 1000

 aggaagacaa ttggggggaa atgccgggag tacagacgac gtcaccgtat 1050

 atcttctttt cggccagtgg aggatatcac cgaagaggac ttagaaaatg 1100

 ttgccataac tgttcgagat aaaatctatg ataaagttct gggtaacacg 1150

 tgccatcagt gtcgacaaaa gaccatcgac accaagacag tgtgtcggaa 1200

 ccagggttgc tgtggtgtgc gaggacagtt ctgtggacca tgcctgcgga 1250

 accgctatgg ggaggatgtc agatcggcat tgctggaccc ggattgggtg 1300

 tgtcccccct gtcgtgggat ctgcaattgc agctactgtc ggaagcgtga 1350

 cggccgctgt gccacaggaa tcctcattca tctggccaag ttttatggtt 1400

 atgacaatgt taaggaatat ctggagagct tacaaaagga gctggtagaa 1450

 gacaattaag aggaaaacaa acagaaccag ccacctcacc atagagtact 1500

 ccaacaagac atgcatacca ttggtgccta agatttatta aaacttgact 1550

 gaacaaaagg ggaccatcaa cattgtagac actggaggcc ttacagagtg 1600

 ctagcctctt ccttcaggac tcacctgggg cctgctgctt ttatattttg 1650

 aaagagttta agggctaata atttaatttg ttgtttgtta aaaattaaaa 1700

 tctccgttct ttccggctgc attgcttttg catgttcaca tatgatgtac 1750

 ttttatgatg tacttttttt tttttgagat ggagtcttgt tctgttgccc 1800

 aggagggagt gcagtggtgc aacctcggct cactgcaacc tttgcctcct 1850

 aggttcaagt gattctccta cctcctgagt aactgggatt acagtcgtgt 1900

 gccaccacgc tcagccctga gttagtttct agtatttttt tctgactttc 1950

 actctaagga tagcgttgaa aaaagaatgc acgtgtgagt tactaaaaag 2000

 ttagaataat gtgcatggga acagtgcagc aacatgctag aaaatcctca 2050

 ctgcactcca gcagaggcta gaggaatgcc agtgttacct tacgcttcta 2100

 gaagcagagc cactccagcc agaacccatt ttgcagtctt ctcttcgctc 2150

 ttcagcctga aggtccagat gtagctgggg cctctcagtt tggttctata 2200

 cacagggcac tcgtaggtct gtttggtttc ttgtctgtcc acgggggtgg 2250

 cttttgcaaa gatgaccggc atagggcatg ccagctcctt gagacgggct 2300

 tcaacaatgg ttcctgcttg ggtgtcccag cgggcgccta tggcaaaaac 2350

 acagcggttg caattgtgtg gcagcttgct actaatgata atgatcaagt 2400

 tgtttgatgc aataaacatt caacattctg gttttgtcat 2440

<210> 4127
<211> 268
<212> PRT
<213> Homo sapien

<400> 4127
 Met Glu Leu Ala Thr Arg Tyr Gln Ile Pro Lys Glu Val Ala Asp
   1               5                  10                  15

 Ile Phe Asn Ala Pro Ser Asp Asp Glu Glu Phe Val Gly Phe Arg
                  20                  25                  30

 Asp Asp Val Pro Met Glu Thr Leu Ser Ser Glu Glu Ser Cys Asp
                  35                  40                  45

 Ser Phe Asp Ser Leu Glu Ser Gly Lys Gln Gln Asp Val Arg Phe
                  50                  55                  60

 His Ser Lys Tyr Phe Thr Glu Glu Leu Arg Arg Ile Phe Ile Glu
                  65                  70                  75

 Asp Thr Asp Ser Glu Thr Glu Asp Phe Ala Gly Phe Thr Gln Ser
                  80                  85                  90

 Asp Leu Asn Gly Lys Thr Asn Pro Glu Val Met Val Val Glu Ser
                  95                 100                 105

 Asp Leu Ser Asp Asp Gly Lys Ala Ser Leu Val Ser Glu Glu Glu
                 110                 115                 120

 Glu Asp Glu Glu Glu Asp Lys Ala Thr Pro Arg Arg Ser Arg Ser
                 125                 130                 135

 Arg Arg Ser Ser Ile Gly Leu Arg Val Ala Phe Gln Phe Pro Thr
                 140                 145                 150

 Lys Lys Leu Ala Asn Lys Pro Asp Lys Asn Ser Ser Ser Glu Gln
                 155                 160                 165

 Leu Phe Ser Ser Ala Arg Leu Gln Asn Glu Lys Lys Thr Ile Leu
                 170                 175                 180

 Glu Arg Lys Lys Asp Cys Arg Gln Val Ile Gln Arg Glu Asp Ser
                 185                 190                 195

 Thr Ser Glu Ser Glu Asp Asp Ser Arg Asp Glu Ser Gln Glu Ser
                 200                 205                 210

 Ser Asp Ala Leu Leu Lys Arg Thr Met Asn Ile Lys Glu Asn Lys
                 215                 220                 225

 Ala Met Leu Ala Gln Leu Leu Ala Glu Leu Asn Ser Met Pro Asp
                 230                 235                 240

 Phe Phe Pro Val Arg Thr Pro Thr Ser Ala Ser Arg Lys Lys Thr
                 245                 250                 255

 Val Arg Arg Ala Phe Arg Arg Asp Arg Ser Arg Gly Val
                 260                 265

<210> 4128
<211> 1939
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 108-139
<223> Unknown base

<400> 4128
 gtggtagagg aggtttccaa ggcaggggag attatggtgg aagagggggt 50

 tatggtggaa gagggggcta tggtggaaga ggctatggag atcccatatg 100

 gcaggcannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc aggtggatat 150

 agaagatact aaaaactata aaaattagat agcagtgctt gcttctttat 200

 agatacatta gaaatagtgt tccaaataac atacttgaat atcatctttg 250

 aagtaaacac catgttagac tccctggtga taccactctt gaattggtta 300

 atatgtaaga acattgtttt ttattaccag ttgatctctc aaatgaagtg 350

 atgacttttt ccatattctg tgtacccttg agcatgttgt gtctttttaa 400

 aaaacaaaaa aaagaacaaa aattattttt taaaatgtaa atatttatta 450

 ccatcagact tggaaaatgg aaagtatttt attgtcatga ttgaatttag 500

 attgttacct gtattttgtt caggtttgag acatataaaa gaccccacct 550

 gtaatagaaa ggaatataga cccttgcctc acctgtattg ctgtggatgt 600

 gttttgtggg tttttcattc gattttacaa aatagggaaa ggcacttcca 650

 gttgtattta gtaggcagtt gttgtgaatc atttttttct cttataggag 700

 gagattcctc tctagccatg tttctgttaa agtttcatta attgaagccc 750

 aagtttactt tttactgtac atacttattt tctaattgga tttgaaatca 800

 gcatgatttt gtttgacaaa gcaaagttta agattgaggt cagaaatact 850

 ttaatggagc aaagacacat accaacttta catgacggtg tgagaaatag 900

 tcctataaac tggtctcttc atcatttatg ctctcacttt agatatccaa 950

 atattaaaag gcaggctgac ctgtatcaca cagaattaag gcagtaattt 1000

 tctgcttcag tagatcaagg gtagggctaa ggcatcctgt ggtaattctg 1050

 attcacagct agatttggga aacacaaagt tagggaatgg ctatatgtga 1100

 tttgctagtt ggagcagtca aagtcttagc tatcaagagt tgtgaatttg 1150

 aatcatggca ctaggtcagg ggtgctatgg attgaaatga ccttagttct 1200

 caaggagtga tttgtcctca tttgtcaaat gaggaatgag acacttacca 1250

 tcatctcagg ttgtttctta aagacctaaa tacaaataca atttgttaaa 1300

 aacttacaga gggcctattt tgaatgcttt aagatgtagg ccaagtaatg 1350

 tatttttctc ttagtgtaga aagttaagag aaaaagagct ggtaccataa 1400

 attttttcaa tcttagtgta aaatctgtat ctcattgtag gcttctggtc 1450

 aatacctata cataacaact taatgtgatc taaccaactc aactgataga 1500

 aagctgaatt gttcccagtg gacaagtggt atttgatgtt tagcaggttt 1550

 ttttgttgtt atttttttgg taaactctgt ggtaaaatct aaaataatgt 1600

 taaaacccta aaagtaacta ttgaatattc tgtaatctta gacatgtatt 1650

 tttcaagcta accctttgaa gaaatgtgtt caaggtagga aaatataaaa 1700

 ttttttggtt atttgtaaat ttattttttg tgtgtttata tttaatgaaa 1750

 agatgtaatt tcatttgtga tagctgaaaa aaaggctttc cataattaag 1800

 aaaatacctt tatcagtagc tatgaactct gaaaaataat ttttaaaaac 1850

 ttttaagaaa aaaactactt gagtaaaata tttcaagagt tgtttaaaaa 1900

 tcttctttaa aacctttaca tttctgcctc acttctttt 1939

<210> 4129
<211> 84
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 108-139
<223> Unknown amino acid

<400> 4129
 Met Ile Glu Phe Arg Leu Leu Pro Val Phe Cys Ser Gly Leu Arg
   1               5                  10                  15

 His Ile Lys Asp Pro Thr Cys Asn Arg Lys Glu Tyr Arg Pro Leu
                  20                  25                  30

 Pro His Leu Tyr Cys Cys Gly Cys Val Leu Trp Val Phe His Ser
                  35                  40                  45

 Ile Leu Gln Asn Arg Glu Arg His Phe Gln Leu Tyr Leu Val Gly
                  50                  55                  60

 Ser Cys Cys Glu Ser Phe Phe Ser Leu Ile Gly Gly Asp Ser Ser
                  65                  70                  75

 Leu Ala Met Phe Leu Leu Lys Phe His
                  80

<210> 4130
<211> 15059
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 9210-9228
<223> Unknown base

<400> 4130
 cgcccggccc cctcccccgg cgccggccac gggaggcggt gatgcgggcg 50

 cgggcggcct cggctgcgcc gagagcggag acacaggctc aagatggcag 100

 attccgactg aggctggggg ggccgagctc gcgcgccgct ttcccgtccc 150

 cgttgccatg aaccgcggac accccggccc cgatggcccc cgtgtacgaa 200

 ggtatggcct cacatgtgca agttttctcc cctcacaccc ttcaatcaag 250

 tgccttctgt agtgtgaaga aactgaaaat agagccgagt tccaactggg 300

 acatgactgg gtacggctcc cacagcaaag tgtatagcca gagcaagaac 350

 atccccctgt cgcagccagc caccacaacc gtcagcacct ccttgccggt 400

 cccaaaccca agcctacctt acgagcagac catcgtcttc ccaggaagca 450

 ccgggcacat cgtggtcacc tcagcaagca gcacttctgt caccgggcaa 500

 gtcctcggcg gaccacacaa cctaatgcgt cgaagcactg tgagcctcct 550

 tgatacctac caaaaatgtg gactcaagcg taagagcgag gagatcgaga 600

 acacaagcag cgtgcagatc atcgaggagc atccacccat gattcagaat 650

 aatgcaagcg gggccactgt cgccactgcc accacgtcta ctgccacctc 700

 caaaaacagc ggctccaaca gcgagggcga ctatcagctg gtgcagcatg 750

 aggtgctgtg ctccatgacc aacacctacg aggtcttaga gttcttgggc 800

 cgagggacgt ttgggcaagt ggtcaagtgc tggaaacggg gcaccaatga 850

 gatcgtagcc atcaagatcc tgaagaacca cccatcctat gcccgacaag 900

 gtcagattga agtgagcatc ctggcccggt tgagcacgga gagtgccgat 950

 gactataact tcgtccgggc ctacgaatgc ttccagcaca agaaccacac 1000

 gtgcttggtc ttcgagatgt tggagcagaa cctctatgac tttctgaagc 1050

 aaaacaagtt tagccccttg cccctcaaat acattcgccc agttctccag 1100

 caggtagcca cagccctgat gaaactcaaa agcctaggtc ttatccacgc 1150

 tgacctcaaa ccagaaaaca tcatgctggt ggatccatct agacaaccat 1200

 acagagtcaa ggtcatcgac tttggttcag ccagccacgt ctccaaggct 1250

 gtgtgctcca cctacttgca gtccagatat tacagggccc ctgagatcat 1300

 ccttggttta ccattttgtg aggcaattga catgtggtcc ctgggctgtg 1350

 ttattgcaga attgttcctg ggttggccgt tatatccagg agcttcggag 1400

 tatgatcaga ttcggtatat ttcacaaaca cagggtttgc ctgctgaata 1450

 tttattaagc gccgggacaa agacaactag gtttttcaac cgtgacacgg 1500

 actcaccata tcctttgtgg agactgaaga caccagatga ccatgaagca 1550

 gagacaggga ttaagtcaaa agaagcaaga aagtacattt tcaactgttt 1600

 agatgatatg gcccaggtga acatgacgac agatttggaa gggagcgaca 1650

 tgttggtaga aaaggctgac cggcgggagt tcattgacct gttgaagaag 1700

 atgctgacca ttgatgctga caagagaatc actccaatcg aaaccctgaa 1750

 ccatcccttt gtcaccatga cacacttact cgattttccc cacagcacac 1800

 acgtcaaatc atgtttccag aacatggaga tctgcaagcg tcgggtgaat 1850

 atgtatgaca cggtgaacca gagcaaaacc cctttcatca cgcacgtggc 1900

 ccccagcacg tccaccaacc tgaccatgac ctttaacaac cagctgacca 1950

 ctgtccacaa ccagccctca gcggcatcca tggctgcagt ggcccagcgg 2000

 agcatgcccc tgcagacagg aacagcccag atttgtgccc ggcctgaccc 2050

 gttccagcaa gctctcatcg tgtgtccccc cggcttccaa ggcttgcagg 2100

 cctctccctc taagcacgct ggctactcgg tgcgaatgga aaatgcagtt 2150

 cccatcgtca ctcaagcccc aggagctcag cctcttcaga tccaaccagg 2200

 tctgcttgcc cagcaggctt ggccaagtgg gacccagcag atcctgcttc 2250

 ccccagcatg gcagcaactg actggagtgg ccacccacac atcagtgcag 2300

 catgccaccg tgattcccga gaccatggca ggcacccagc agctggcgga 2350

 ctggagaaat acgcatgctc acggaagcca ttataatccc atcatgcagc 2400

 agcctgcact attgaccggt catgtgaccc ttccagcagc acagccctta 2450

 aatgtgggtg tggcccacgt gatgcggcag cagccaacca gcaccacctc 2500

 ctcccggaag agtaagcagc accagtcatc tgtgagaaat gtctccacct 2550

 gtgaggtgtc ctcctctcag gccatcagct ccccacagcg atccaagcgt 2600

 gtcaaggaga acacacctcc ccgctgtgcc atggtgcaca gtagcccggc 2650

 ctgcagcacc tcggtcacct gtgggtgggg cgacgtggcc tccagcacca 2700

 cccgggaacg gcagcggcag acaattgtca ttcccgacac tcccagcccc 2750

 acggtcagcg tcatcaccat cagcagtgac acggacgagg aggaggaaca 2800

 gaaacacgcc cccaccagca ctgtctccaa gcaaagaaaa aacgtcatca 2850

 gctgtgtcac agtccacgac tccccctact ccgactcctc cagcaacacc 2900

 agcccctact ccgtgcagca gcgtgctggg cacaacaatg ccaatgcctt 2950

 tgacaccaag gggagcctgg agaatcactg cacggggaac ccccgaacca 3000

 tcatcgtgcc acccctgaaa acccaggcca gcgaagtatt ggtggagtgt 3050

 gatagcctgg tgccagtcaa caccagtcac cactcgtcct cctacaagtc 3100

 caagtcctcc agcaacgtga cctccaccag cggtcactct tcagggagct 3150

 catctggagc catcacctac cggcagcagc ggccgggccc ccacttccag 3200

 cagcagcagc cactcaatct cagccaggct cagcagcaca tcaccacgga 3250

 ccgcactggg agccaccgaa ggcagcaggc ctacatcact cccaccatgg 3300

 cccaggctcc gtactccttc ccgcacaaca gccccagcca cggcactgtg 3350

 cacccgcatc tggctgcagc cgctgccgct gcccacctcc ccacccagcc 3400

 ccacctctac acctacactg cgccggcggc cctgggctcc accggcaccg 3450

 tggcccacct ggtggcctcg caaggctctg cgcgccacac cgtgcagcac 3500

 actgcctacc cagccagcat cgtccaccag gtccccgtga gcatgggccc 3550

 ccgggtcctg ccctcgccca ccatccaccc gagtcagtat ccagcccaat 3600

 ttgcccacca gacctacatc agcgcctcgc cagcctccac cgtctacact 3650

 ggatacccac tgagccccgc caaggtcaac cagtaccctt acatataaac 3700

 actggagggg agggtgggag ggagggaggg agagaatggc ccgagggagg 3750

 agggagagaa ggagggaggc gctcctggga ccgtgggcgc tggcctttta 3800

 tactgaagat gccgcacaca aacaatgcaa acggggcagg tgcggggggg 3850

 gggggggcag agggcagggg gacggggtcg ggacaccagt gaaacttgaa 3900

 ccgggaagtg ggaggacgta gagcagagaa gagaacattt ttaaaaggaa 3950

 gggattaaag agggtgggaa atctatggtt tttatttaaa aaaggaaaag 4000

 ggaaaaaaaa aaaggtcaat aacaaaaaac ccagctcaag aacccattct 4050

 acgccaaact ggaaaggaga agagagcaac aggaagattc cagaaacggg 4100

 gggccccagt ttttgaagaa ctttatgaac ttttcaaaga ttattttcat 4150

 atggcagcaa gtgatacgga agactgctgt cagggacacc tgatatggaa 4200

 atcaaataga tttttaatta attgaacata agatttaggg atttttccag 4250

 aactcgaaag ggtcaacagc cctccagaat gtcgggctgc agcctgagga 4300

 ggctgatgtt tggagctggt gtgggattgg cgaagcccag tccgggctcc 4350

 ctagtcagga aagacggggg acggccaggc tgctggaagg cccccggggg 4400

 cgcggggcga gttttctttt tctgagcact ctggataaat ccctaagcaa 4450

 cgttgtttct caaatgtcat taataatgtg tgttgcaaac tttaggtttt 4500

 tttcttttct gaaaatgtat tttctctttg aatccacccc tagtcgcgta 4550

 gcgtagggct agcggtcgtc acagacaccc tagtagaatg tagcactcag 4600

 cacccttgtc tcctaccttg tgttcaactc caatgatacc aatagaatat 4650

 tcctcaatgt aattgcacaa aaaaaagcga tataacatag gcatgtaacc 4700

 aatgtggcgg tgcaggtgtg cgggtgagcg agcacgtgtg ggtgtgcacg 4750

 cgccgccctc cccgcgtggc cctcggcgcc gccaccctag ctggcgcagt 4800

 cttgacactg catccttccc tcctagtgcc ttaccgagcg acagacgcgg 4850

 cgtgagggtt tacttccact ggtactccaa gaaactgagg ctagtcagac 4900

 acaatctcag ctcttctgtt gtgctgttgt aacagtttac gctggccttt 4950

 tttttttctt tttctttttc tttttaaaat gttaatgccc gttgtctttc 5000

 ctgggctgtt tgctagcgga aggatgccag ggaagccagc aggagctagg 5050

 agagagtccg tggatctcga aagaaatatg ggagacagat gcccggcggg 5100

 tgcgtctgga gatggggacg gcgggagttg agttgtggca gtagttgagt 5150

 tgtaatttgt gggcggaggc ccagagagac tccccaccct tcacccctgc 5200

 cccactctgt ccccagttcc gccatttgtg aggccagagg tttccggact 5250

 gttggcctcg ccaggcagcc gtctcccgcc ccaggcggca tcccccagtc 5300

 cctcccgcct ccacgagagc ctggagctct cagcctcgcc cggggctcca 5350

 ctctctcctc cggctccctg ggctgttttg ctctaacgat cttgccagat 5400

 ccctccctct gtagacaacc accaacctct gtttgctgtt gaattctctc 5450

 ctcacattac ccaggtctgc tcaagacatg attttggttt tggtttctga 5500

 gggttctagt gggcagaagg ttggagggac acttatgagg gtggccgggg 5550

 gtctgacgct gcactttgga aaaactcaca cagttgaatt tccaaagaaa 5600

 tctgcccttt gccctctttg cacctttgat acattctgga agttttctca 5650

 ggctttggac acttctgggg atggaggtgt ggagaagtgg ggagttccct 5700

 ctcttcatag taaataactc tgaaatatgt gaatgtgaat ggcaggagaa 5750

 tctggccaag gatggggccg aaaagggtgg ttctaattgt ttgcttctga 5800

 tgttgagtct ttagctgacc ccacaggcag gtttccaagg tgcaaagaga 5850

 tctttcccga gtcagcggcc ccatcctcat cctccctccc tttacttcct 5900

 cactgtgcag tctccctcaa ggatctactg tgaaaggtgt gtttgtagtg 5950

 atatccaacc taactcagta acgaagtcgt tacttagctc ttagctgtga 6000

 aataactctg gaaacttccc caccccaacc ataaattctt acttataaag 6050

 aaacaggtcc ccaaactgga aacagcttag tccaggcctc agcgagaagg 6100

 aaggacacca tgactgctcc atgctgggca cagccgggca gtcttgccaa 6150

 gtgcctgctg gaggctgtgc cggcaagagg cctgcagcaa ggagattccc 6200

 ttccctcggg ccattatcaa tactgtcttt atctggaggt ggggaagcgc 6250

 agccctctga gacagcagga caatggtcag ttcagagagg gtgagggcag 6300

 caaacgcttc agaggacaca gaagccagag gacccccccc cgccccacag 6350

 ctgggtcagc ctggaaaatc catctattag ggactttttg gcagccagat 6400

 ggcagcaata gcccattagg tctcatcccg agttccaagt cttggctgca 6450

 aatgagcctc agttcgcctt actggagagc acccccagat tcctgggcac 6500

 agttcatttc cagccctttc tagatctgat cttttagggg gaaagacagc 6550

 ttaaaatgtt cttttcattt taaagaaaat tattctgtct gcttaagttg 6600

 gaggctactt actctttcac ctgacatttt ctttcctttt attcttccag 6650

 atcaggaatg aaatttccat gctgctcata aagataatat tattgtacta 6700

 attattttta ttaccattgt aattatgatc attatgttga tattttagtc 6750

 agggttttaa atgcacattt attccaagta tctttgtgtt ttctctttaa 6800

 tatttaaact tattctctct gtgagtatat aagtagactg gagggacatc 6850

 cagatgtcca gttttgtcag gccaaaaaaa aaaggaaaga cttaggaagt 6900

 aggaaaattg tttctgtcat ctctatccca acaagagacg tcaagaaaga 6950

 tccaccacag aacaaaagtt taaagaagaa tcaaagcctt gattgggctt 7000

 ctgacaacat ggtcaccatc aaggttgtca ttttctagat cccagaggcc 7050

 tgggatgcga cgtcaggtgg catctcatgg gctcggggaa tgtcgagtca 7100

 ctgactgtcc agcccttagc cagcttctct cccacatcct cagagctctc 7150

 ctgtgcttct gaaatctgtt aactaaatct ttggcttgcc tctggtattt 7200

 aagcaagaaa attccctccc agaggtgacc ccatccgctt ccccacaatc 7250

 catccttttg ccatcggcgc acctggggcg tggcttaggt tcttcaatgc 7300

 agggacattt gccccctccc agaagctgct gggcacagtg aggtggcgta 7350

 agagtgactg gcaggtggta ccttccccag gaaatttcac cacaccaccc 7400

 agttcctcag cctgccccct ccccctgtga tgcatgcccc cagcacccaa 7450

 ttctagccag ctggaagtgg gtggagggac agcaggaggc cagagaaacc 7500

 ctgaacaaag ctgggcggct gctcaggcat cacaggctgc accccctctg 7550

 aaagcatccc cactgggctc cggccacatc ttcagtgcac tgtgctgtgt 7600

 gcgctgggtg ctcacacgct gtccccagac ccacaaagtg ctaggcccca 7650

 gttgaagaaa ggggtgaaat agccagcttc accgaaggga agggaaggga 7700

 agtattgggc gatgccagcc ccacagacgc tcagcaaaca ttagtgcaca 7750

 ttctcctagt cctcacccaa tggcctcctc tacccccatg catggagctg 7800

 ccacatcaga agccccaaga gaagctccct gcaggagagg ccagctccct 7850

 ggatgcccaa ttgcatacct ggccgaatct gccattgagt caccttagca 7900

 aataggctgc tgtcactagg accaagctct caagcagagg gatgccaacc 7950

 tagtccttac ttagcccacg aatcatctag agcatcctct agtcttttgt 8000

 gggctccctc cttcccattt gaagagacat tgttcagagg aagaggggaa 8050

 gatttgaaat gtcaggtcac ggaggagtgt ttaactggag cctggtgaac 8100

 cgcagggcaa tttgcttctg ctcactgggt tctgactggc ccgtctggac 8150

 gtgggccccc atgtctctgt gcttagggcc tcttcatgat gttttggatg 8200

 tttccaaggg aagtgggtga gcagatcaag gggtgggaga gtcgaggctt 8250

 gattccagtt aatactgtga agtggagcgt gcggtcagtg gaattcagag 8300

 gaaaaagaag ggttggagca aagcggcatt catctcctgg actgttagcc 8350

 tttctagtct tcctggtggc tgaggtgttc acgggctggg ggagccagct 8400

 gacctttgtc ctcttcaacc tagaagactc agcccgccca gacaccaacg 8450

 tgtgagacgg atggacatca ggaagggaag gggagattag cccaactgct 8500

 gacagaacga tttcccttgg ttggaccttg ggaatggcaa acactcatat 8550

 tggaacaagc ttggggtgga agatttaggc cgtgtgagcg tgtgtgagtg 8600

 agtggaacaa actttcttgg aaactggagg gaggagatga ggaggcttcg 8650

 ggaagtatta ctgatggctc atggttgaga gagcgacgtg gggacccagc 8700

 tcgccccagc ttttgtccca ggttctcttt gtctgatgct gagggcaggg 8750

 tggggtgtgg gaccaccact cttgttggcc tgtcaagtag accctaggac 8800

 agaaaatgga aagaaggaaa tggctcggtg ctctcaacta gcagagagaa 8850

 ttgaggagag gtaagggttc cttctgcagg ccagcctggg actccacagc 8900

 gccagcagga gtgacttggc cacaagacat tccagcccca gggactttgc 8950

 aggcttcatt ccctgtctgt gtcttttcct tctggtgtgt tttacagact 9000

 tctgatgggg aagcttcaaa cttgagcagg ccagagatgt ccttaccaaa 9050

 ttggaaagga aggtgaaact gttcctttct ttagccaaag aacccttctc 9100

 aaagacgcct ccagaaatgg acaaaatggc cttcccttcg ttcctttcca 9150

 ggcaataatg acatcattag tgatgcaatt ctatttgtct ttctctttcc 9200

 tctctgtccn nnnnnnnnnn nnnnnnnntg catttatttc aaaactgtgc 9250

 tattctttta agaggagtgg aggtgacccc ttcgatgctg ctgctatcgg 9300

 gagacaaggt gccataccaa tacgtgggct tgactaatcc caggccacca 9350

 tgggagagag caaagcaggg ctgccaggag ttcagttgca tcaagggcgt 9400

 agagcacgcg ggggctgggc tcggaatagc agtacttttc cactttgatg 9450

 ccttagaact ctcacttctc atctccacag accagactca gtaaaatctc 9500

 aggccactag agaatggaag gcggtgaaac aggatttaaa tgcaaaaaaa 9550

 acctattgga ggcttttggc accgtggctc actagaggga cccagcatag 9600

 tagaggtttc tcttgttgca gcttctgaaa agttcaaaaa agaactccag 9650

 gccgttcttc cctcaaaccc agtgagagtt tgcagagaag tgccccctgc 9700

 agggctcccg tcccagaaca ccagcaccag agagggtctt cccgatgccc 9750

 cccgctggac ttgcccaagc ctctgggagc ccctcatctc agatccctgt 9800

 gttgaacatg acactgactg tcccttattt gttaaaattt gcaatatctc 9850

 tcaagtaaat aatagccaac atttgttgaa tgctttcatg actcccgggc 9900

 taaggccttt atgagcgttg tctcaagggg ccccaacagc catcccacag 9950

 ggagggggat aacagccccc atttatagat aagggagctg accggatgct 10000

 ctgagaagtg gcaggtgttg aaggaaggat aaagcagtga tgggccagaa 10050

 tccccaaggt tccctttttt gttcatcagg cccttcctga gatgtgattt 10100

 ttaatctttt aacttttttt aattaatagc aatgcgtggc ctcatatttc 10150

 tatgaaccat ttagtgatac tcccgcttcc tgcatgccac acactgtgct 10200

 gggaattgct catgggttgt cctgtttcat cttctccgta gccctgtgag 10250

 atcggcaata ttagtccccc tacagccaag gaaactgccc agagccacac 10300

 aactcttgag gggcgaggag ggcttgaacc tgagtctgcc cagctccaga 10350

 actgagcttg cagccattag ccacagctgt ctcctgcatg tctgagcaaa 10400

 gaaaggcctt tacacagcat caccctgtgc catcccatgc accgtgggac 10450

 tcagctaaag gactgtgcaa agagggggct cctgagttgg atttaggcaa 10500

 aaggggcaga attcgtttga tttttagaga aaatctctgg agagtttctt 10550

 ttgattcata gaattccttt tagatttctt tccagcatac caactagctt 10600

 tagtagtgct gctacaacca gctcttataa gtaagagtga aaaagtattc 10650

 ttttcttctt taaaaaataa gtttttcttg cttatagtta attctagaaa 10700

 ggcaatacta aaggtatata tttttttcaa aatgctattt tttactgcac 10750

 ttgataatta tcctgacagc tctgatctct gtaatagatt cactcttcag 10800

 ctctgggcag aaccagaggc agggttcaca ccaaatttgt aaataccata 10850

 tgtgggtctg gtgtccagga acttttttct ttctgttaaa aaaaagaaca 10900

 aaaaaagaac aaaaaaaaag aagtagaggt ggaagaaaga caagacttag 10950

 aggaacaaaa gaatgttttc ttttgagata ctcttctcaa agaaatagca 11000

 acaattgtat aaacaggaaa accagccagc tttcatgata aaaggaaggc 11050

 gtgtctcttg ccctggtatg agattaacag aaatacagat gcatttttat 11100

 tttgattgaa agatggtgag aatgtagaaa tgcttaggac tagattttta 11150

 attttttaaa ataactatta tcatttatta tgaaatattt gttcagttgt 11200

 tttgagtggg tttcttgtcc cttttttcat ttaaaacctt ctttgttgac 11250

 tggctccagg cttgtttgcc taaattctta ggtagtttac acaagttcta 11300

 gaatctttta gaactttaac tccattggaa gcaaacctaa ctaatcggag 11350

 tttgagatcc tggttggttt caataggtat tctggaattc tggcagaaca 11400

 cctaaagatt tttttttttt ttagaaggtt ttagatacat tatcttacac 11450

 aaactgtgac ctaatggcaa taattacctc aaatgtgggc attcatcctg 11500

 gttttagcct tttttgaaat catgtagcca gcttgatctt ggaatttaaa 11550

 gactatgaat tctctgtggg ctgaaaataa tgattacttc atacccccgg 11600

 tcatcgttgc ttaagtgaat tctgaaaata gctcatcttt acaacaaaaa 11650

 ttaaaccaag gaagagatta ttctttgtgt gttgtactca aatgcgatgt 11700

 tcaaatgcac atgttaagta tatatgtttt tagctactgt aaaatgctgt 11750

 tagccttcta agctatcaaa acagtcacat tttaaatgag taaactaaac 11800

 aattgactgt ggatacttaa gcatatttct ggctacgttt tatagttaaa 11850

 gtgttttata gtttacattt agactggtac tttttaaaga aaagttctgt 11900

 ttataactga catccgcaaa ccccagtgaa tgcctcttag ttggaggttg 11950

 tgtctccccc aaggcaagtg tgttgtccca gactcttctg tagtccagca 12000

 tgcgcacttc cctctggatt attactttcc acgtgaactc aagagaacat 12050

 gaaaggcaat ccagatggag ggaaaaggtg tgagtccgca gcccgggcca 12100

 gatgcgaagg tctcatgcgt gtcgtctaaa cacttgtctt caaggccttc 12150

 tctctgacat cttggaagag tcattgagaa cagataacct ggttcattga 12200

 tttttgtctt gatttgaata tttaacttat taatagatcc actgatttcc 12250

 aggcaccagg cagtagaaga gactgggatt caggtgacca tgaaggcaca 12300

 gctgctactt ctgggccggg ggtgatattt tgatcagcgt tttgtagggg 12350

 aggaccatat acccctattc ccatggtcgc tggctgggtt ttccatatat 12400

 ctgctgtcat ttattcgttt tccccttaaa agcaaaatca atgtaaaagg 12450

 ctatgtttac gttttactca ttgtccagct tagactcaaa gtctagttcg 12500

 gtgggagggg gaccttagca tcctctcaga gatggtcagg gctgagcagg 12550

 aggaggcaga gacagagggg cagctcagcc tggtccattg agacccactc 12600

 taaacagaca tcatatttgg aacaagaaga tgcttcgaga caggaatggg 12650

 ccccactgtc atgcagaaac agactggggg aatggcagtt tccctgagtc 12700

 ttggtttctt ttatgttttc tcttgtgcca ccaccaaact gcagaggacc 12750

 tgctgtgacc taaagggcat tcctttagca gataagacct tgaaaactgc 12800

 aaaacacctg ggaccaggga gcttttaaaa aatacaaaaa aataccacat 12850

 ttgctttttc cctgtgaact gtattgacag cgtgttctta ggacagtctt 12900

 ttggtggaaa tgttactgta aaatagtttt catctcaccc ctcctaatca 12950

 tactcccact ttcctgtttg tgtggtggtg ttgctgtttt ttcctttaca 13000

 tgaattaacc aaatgaattt tgtgtcattg tttttggggc ttatattttt 13050

 aaaacataga aattgccttt tgttcatttg aaaagtaagt atgttgtatc 13100

 tgaaaaaggg ctctgcctct gctctccctc gcttccttgt aaccaatctc 13150

 caaacgaatc tctcctggca ccgccccctt ccttatatag ggtcactgtc 13200

 cccggggcca cctctgcctc caccctgctg tcaccactgc cctgggccaa 13250

 ggcacccagg actcccagaa agcgcgagag ccagcaagaa ggccccactc 13300

 agccttgaga ctggtggtca cacctccctg tcagagtcgc ctgctgggct 13350

 gaaggggcaa tggattgtca ttgttgaaat tgtttggctc aggttataag 13400

 gaggaacttg ggaagtagaa agtgacttga ccatgtgcat ccttggtagc 13450

 ttcctgtaac taacaaatgg aacagagagc acacccccgc cccgccccac 13500

 cccaagcaga tgttcccgtc agcgctgccc tgagtcagtc ggtcccccgt 13550

 ttctgctctc ctcccttttg tgttcctgct cacttcaagc ttcttccatg 13600

 gactttccag ggcacagtca tctctagccc ccaaatcatc tcttcatcct 13650

 ctgtgtgtgc atttttttaa ccaaatgaaa tagacaagaa agtcatactt 13700

 tggggcagca gaatttctaa tttagtagaa tcactgtata gagatagatg 13750

 ttgatatata tgtttgtgta tatatatcaa accaaattgg ataggagaag 13800

 tatagcttta cagatgagga gaaggagctc tttagaggtc ggagtcaaga 13850

 ctggtgtctt ggacgtgcat gggctgtgtc ccaggccact ccgcacacat 13900

 ggggctgagg cgtggcgccg ggcccttgtc atccacctca ccacggcaga 13950

 gccagcaggc cctgtagggt gctgctgctg tctcactggg tcccagcttc 14000

 aagcgcatca gtgggtgacg ggggcaacaa atcagagtga ctggaagttt 14050

 ccatcccgtt ttgctttgac cacgtgtact gagctgcagc ctctgatact 14100

 ctgtcacgtt tccaaaaatg gtatccatta ggatagaaag agaatggatc 14150

 tgcagaaatg tttacctttc aactgctcat gaattcagga cactggatag 14200

 aaagactcac tccccaaaat gagaacaggg aagaggagac ccggcgacac 14250

 taagtcacca ggtccaagga acgtggctcc ctccccaggg tcatctcacc 14300

 tagatctttc tctcccaggt catctcagct caatctcaat aaccctatga 14350

 aagccctggt ctgttgtgtt ccttcaccgt acggtttctg taataaaaag 14400

 tgttaatcca tgttaatctg tgtgaaaatt attgcgtgca acagtatttt 14450

 ctcgtgtacc tctttttcct atgtgaattg tccctctttt ttatttataa 14500

 atgtctactt ttgttttttt aaagacaaac caatgtgttg tagacctata 14550

 tgtaacctat tccttagtct catattatag gtatgttata agaatggata 14600

 ttttacttgg ctttagaatg ttttacaaga aaactaattc ttaactgatc 14650

 aagtccttgc tactaaaatg cttgtgtttt tcatcatgac gtcgtgtgct 14700

 tctaaattaa tcattttcgt tgtagaaaaa tggagtgaat ttatattagt 14750

 cttggaaact aataatagca ttgtaaattt atgagatgat tttaacagaa 14800

 aaaatataga agaatatagt tattttaatt gtaatattac taactgtagg 14850

 gtgagaaaaa gggggggggg tcccattgtg gtgaactatg ttatagcttg 14900

 ttactcatag tttctttttg atcatttttt cggtctccga ggtgaaatga 14950

 cttattaatt aaaatttgta aactcacata tgcatattgt atatgtgtag 15000

 aaatgtaatc acactttgtc ttggaattac attaaactgt ttgaaatcac 15050

 tgtaaaaaa 15059

<210> 4131
<211> 1171
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 9210-9228
<223> Unknown amino acid

<400> 4131
 Met Ala Pro Val Tyr Glu Gly Met Ala Ser His Val Gln Val Phe
   1               5                  10                  15

 Ser Pro His Thr Leu Gln Ser Ser Ala Phe Cys Ser Val Lys Lys
                  20                  25                  30

 Leu Lys Ile Glu Pro Ser Ser Asn Trp Asp Met Thr Gly Tyr Gly
                  35                  40                  45

 Ser His Ser Lys Val Tyr Ser Gln Ser Lys Asn Ile Pro Leu Ser
                  50                  55                  60

 Gln Pro Ala Thr Thr Thr Val Ser Thr Ser Leu Pro Val Pro Asn
                  65                  70                  75

 Pro Ser Leu Pro Tyr Glu Gln Thr Ile Val Phe Pro Gly Ser Thr
                  80                  85                  90

 Gly His Ile Val Val Thr Ser Ala Ser Ser Thr Ser Val Thr Gly
                  95                 100                 105

 Gln Val Leu Gly Gly Pro His Asn Leu Met Arg Arg Ser Thr Val
                 110                 115                 120

 Ser Leu Leu Asp Thr Tyr Gln Lys Cys Gly Leu Lys Arg Lys Ser
                 125                 130                 135

 Glu Glu Ile Glu Asn Thr Ser Ser Val Gln Ile Ile Glu Glu His
                 140                 145                 150

 Pro Pro Met Ile Gln Asn Asn Ala Ser Gly Ala Thr Val Ala Thr
                 155                 160                 165

 Ala Thr Thr Ser Thr Ala Thr Ser Lys Asn Ser Gly Ser Asn Ser
                 170                 175                 180

 Glu Gly Asp Tyr Gln Leu Val Gln His Glu Val Leu Cys Ser Met
                 185                 190                 195

 Thr Asn Thr Tyr Glu Val Leu Glu Phe Leu Gly Arg Gly Thr Phe
                 200                 205                 210

 Gly Gln Val Val Lys Cys Trp Lys Arg Gly Thr Asn Glu Ile Val
                 215                 220                 225

 Ala Ile Lys Ile Leu Lys Asn His Pro Ser Tyr Ala Arg Gln Gly
                 230                 235                 240

 Gln Ile Glu Val Ser Ile Leu Ala Arg Leu Ser Thr Glu Ser Ala
                 245                 250                 255

 Asp Asp Tyr Asn Phe Val Arg Ala Tyr Glu Cys Phe Gln His Lys
                 260                 265                 270

 Asn His Thr Cys Leu Val Phe Glu Met Leu Glu Gln Asn Leu Tyr
                 275                 280                 285

 Asp Phe Leu Lys Gln Asn Lys Phe Ser Pro Leu Pro Leu Lys Tyr
                 290                 295                 300

 Ile Arg Pro Val Leu Gln Gln Val Ala Thr Ala Leu Met Lys Leu
                 305                 310                 315

 Lys Ser Leu Gly Leu Ile His Ala Asp Leu Lys Pro Glu Asn Ile
                 320                 325                 330

 Met Leu Val Asp Pro Ser Arg Gln Pro Tyr Arg Val Lys Val Ile
                 335                 340                 345

 Asp Phe Gly Ser Ala Ser His Val Ser Lys Ala Val Cys Ser Thr
                 350                 355                 360

 Tyr Leu Gln Ser Arg Tyr Tyr Arg Ala Pro Glu Ile Ile Leu Gly
                 365                 370                 375

 Leu Pro Phe Cys Glu Ala Ile Asp Met Trp Ser Leu Gly Cys Val
                 380                 385                 390

 Ile Ala Glu Leu Phe Leu Gly Trp Pro Leu Tyr Pro Gly Ala Ser
                 395                 400                 405

 Glu Tyr Asp Gln Ile Arg Tyr Ile Ser Gln Thr Gln Gly Leu Pro
                 410                 415                 420

 Ala Glu Tyr Leu Leu Ser Ala Gly Thr Lys Thr Thr Arg Phe Phe
                 425                 430                 435

 Asn Arg Asp Thr Asp Ser Pro Tyr Pro Leu Trp Arg Leu Lys Thr
                 440                 445                 450

 Pro Asp Asp His Glu Ala Glu Thr Gly Ile Lys Ser Lys Glu Ala
                 455                 460                 465

 Arg Lys Tyr Ile Phe Asn Cys Leu Asp Asp Met Ala Gln Val Asn
                 470                 475                 480

 Met Thr Thr Asp Leu Glu Gly Ser Asp Met Leu Val Glu Lys Ala
                 485                 490                 495

 Asp Arg Arg Glu Phe Ile Asp Leu Leu Lys Lys Met Leu Thr Ile
                 500                 505                 510

 Asp Ala Asp Lys Arg Ile Thr Pro Ile Glu Thr Leu Asn His Pro
                 515                 520                 525

 Phe Val Thr Met Thr His Leu Leu Asp Phe Pro His Ser Thr His
                 530                 535                 540

 Val Lys Ser Cys Phe Gln Asn Met Glu Ile Cys Lys Arg Arg Val
                 545                 550                 555

 Asn Met Tyr Asp Thr Val Asn Gln Ser Lys Thr Pro Phe Ile Thr
                 560                 565                 570

 His Val Ala Pro Ser Thr Ser Thr Asn Leu Thr Met Thr Phe Asn
                 575                 580                 585

 Asn Gln Leu Thr Thr Val His Asn Gln Pro Ser Ala Ala Ser Met
                 590                 595                 600

 Ala Ala Val Ala Gln Arg Ser Met Pro Leu Gln Thr Gly Thr Ala
                 605                 610                 615

 Gln Ile Cys Ala Arg Pro Asp Pro Phe Gln Gln Ala Leu Ile Val
                 620                 625                 630

 Cys Pro Pro Gly Phe Gln Gly Leu Gln Ala Ser Pro Ser Lys His
                 635                 640                 645

 Ala Gly Tyr Ser Val Arg Met Glu Asn Ala Val Pro Ile Val Thr
                 650                 655                 660

 Gln Ala Pro Gly Ala Gln Pro Leu Gln Ile Gln Pro Gly Leu Leu
                 665                 670                 675

 Ala Gln Gln Ala Trp Pro Ser Gly Thr Gln Gln Ile Leu Leu Pro
                 680                 685                 690

 Pro Ala Trp Gln Gln Leu Thr Gly Val Ala Thr His Thr Ser Val
                 695                 700                 705

 Gln His Ala Thr Val Ile Pro Glu Thr Met Ala Gly Thr Gln Gln
                 710                 715                 720

 Leu Ala Asp Trp Arg Asn Thr His Ala His Gly Ser His Tyr Asn
                 725                 730                 735

 Pro Ile Met Gln Gln Pro Ala Leu Leu Thr Gly His Val Thr Leu
                 740                 745                 750

 Pro Ala Ala Gln Pro Leu Asn Val Gly Val Ala His Val Met Arg
                 755                 760                 765

 Gln Gln Pro Thr Ser Thr Thr Ser Ser Arg Lys Ser Lys Gln His
                 770                 775                 780

 Gln Ser Ser Val Arg Asn Val Ser Thr Cys Glu Val Ser Ser Ser
                 785                 790                 795

 Gln Ala Ile Ser Ser Pro Gln Arg Ser Lys Arg Val Lys Glu Asn
                 800                 805                 810

 Thr Pro Pro Arg Cys Ala Met Val His Ser Ser Pro Ala Cys Ser
                 815                 820                 825

 Thr Ser Val Thr Cys Gly Trp Gly Asp Val Ala Ser Ser Thr Thr
                 830                 835                 840

 Arg Glu Arg Gln Arg Gln Thr Ile Val Ile Pro Asp Thr Pro Ser
                 845                 850                 855

 Pro Thr Val Ser Val Ile Thr Ile Ser Ser Asp Thr Asp Glu Glu
                 860                 865                 870

 Glu Glu Gln Lys His Ala Pro Thr Ser Thr Val Ser Lys Gln Arg
                 875                 880                 885

 Lys Asn Val Ile Ser Cys Val Thr Val His Asp Ser Pro Tyr Ser
                 890                 895                 900

 Asp Ser Ser Ser Asn Thr Ser Pro Tyr Ser Val Gln Gln Arg Ala
                 905                 910                 915

 Gly His Asn Asn Ala Asn Ala Phe Asp Thr Lys Gly Ser Leu Glu
                 920                 925                 930

 Asn His Cys Thr Gly Asn Pro Arg Thr Ile Ile Val Pro Pro Leu
                 935                 940                 945

 Lys Thr Gln Ala Ser Glu Val Leu Val Glu Cys Asp Ser Leu Val
                 950                 955                 960

 Pro Val Asn Thr Ser His His Ser Ser Ser Tyr Lys Ser Lys Ser
                 965                 970                 975

 Ser Ser Asn Val Thr Ser Thr Ser Gly His Ser Ser Gly Ser Ser
                 980                 985                 990

 Ser Gly Ala Ile Thr Tyr Arg Gln Gln Arg Pro Gly Pro His Phe
                 995                1000                1005

 Gln Gln Gln Gln Pro Leu Asn Leu Ser Gln Ala Gln Gln His Ile
                1010                1015                1020

 Thr Thr Asp Arg Thr Gly Ser His Arg Arg Gln Gln Ala Tyr Ile
                1025                1030                1035

 Thr Pro Thr Met Ala Gln Ala Pro Tyr Ser Phe Pro His Asn Ser
                1040                1045                1050

 Pro Ser His Gly Thr Val His Pro His Leu Ala Ala Ala Ala Ala
                1055                1060                1065

 Ala Ala His Leu Pro Thr Gln Pro His Leu Tyr Thr Tyr Thr Ala
                1070                1075                1080

 Pro Ala Ala Leu Gly Ser Thr Gly Thr Val Ala His Leu Val Ala
                1085                1090                1095

 Ser Gln Gly Ser Ala Arg His Thr Val Gln His Thr Ala Tyr Pro
                1100                1105                1110

 Ala Ser Ile Val His Gln Val Pro Val Ser Met Gly Pro Arg Val
                1115                1120                1125

 Leu Pro Ser Pro Thr Ile His Pro Ser Gln Tyr Pro Ala Gln Phe
                1130                1135                1140

 Ala His Gln Thr Tyr Ile Ser Ala Ser Pro Ala Ser Thr Val Tyr
                1145                1150                1155

 Thr Gly Tyr Pro Leu Ser Pro Ala Lys Val Asn Gln Tyr Pro Tyr
                1160                1165                1170

 Ile


<210> 4132
<211> 5034
<212> DNA
<213> Homo sapien

<400> 4132
 agcggccgcc aacgccgccc ggactggagc cctgacattg ctgcgctcgg 50

 ggggctccag gcagcccgta tcggggcctt tatttctcgt cggcggcgcc 100

 ctgcaccgcg cctcgcaaag ccaaacacca gagcacccta gaaggtttaa 150

 ctaaaagaat gctcatgttt gacccagttc ctgtcaagca agaggccatg 200

 gaccctgtct cagtgtcata cccatctaat tacatggaat ccatgaagcc 250

 taacaagtat ggggtcatct actccacacc attgcctgag aagttctttc 300

 agaccccaga aggtctgtcg cacggaatac agatggagcc agtggacctc 350

 acggtgaaca agcggagttc acccccttcg gctgggaatt cgccctcctc 400

 tctgaagttc ccgtcctcac accggagagc ctcgcctggg ttgagcatgc 450

 cttcttccag cccaccgata aaaaaatact cacccccttc tccaggcgtg 500

 cagcccttcg gcgtgccgct gtccatgcca ccagtgatgg cagctgccct 550

 ctcgcggcat ggaatacgga gcccggggat cctgcccgtc atccagccgg 600

 tggtggtgca gcccgtcccc tttatgtaca caagtcacct ccagcagcct 650

 ctcatggtct ccttatcgga ggagatggaa aattccagta gtagcatgca 700

 agtacctgta attgaatcat atgagaagcc tatatcacag aaaaaaatta 750

 aaatagaacc tgggatcgaa ccacagagga cagattatta tcctgaagaa 800

 atgtcacccc ccttaatgaa ctcagtgtcc cccccgcaag cattgttgca 850

 agagaatcac ccttcggtca tcgtgcagcc tgggaagaga cctttacctg 900

 tggaatcccc ggatactcaa aggaagcgga ggatacacag atgtgattat 950

 gatggatgca acaaagtgta cactaaaagc tcccacttga aagcacacag 1000

 aagaacacac acaggagaaa aaccctacaa atgtacatgg gaagggtgca 1050

 catggaagtt tgctcggtct gatgaactaa caagacattt ccgaaaacat 1100

 actggaatca aacctttcca gtgcccggac tgtgaccgca gcttctcccg 1150

 ttctgaccat cttgccctcc ataggaaacg ccacatgcta gtctgattgc 1200

 ctctgtgtcc tgcctcagcg tgactcccca ctcacctggc tctctctctg 1250

 tcctgcctcc cattatctaa cacatttttt acatgtacat tttaatttga 1300

 ttcagctggt ctgaatctct gaatttatat catccaaaac ttccatatgg 1350

 tcagtagtag atgttctcta atcctccctc tccttaccac gggtcagacc 1400

 taaagaatgt gaacactttt tttttttttt ctggggatgc taagcaaacc 1450

 cttcttacag atacgtttaa tgtaataaga acaagggaac atgtaaacta 1500

 acataaccaa ttgtcagttc tccatgtatt cctcaaaaga atgtcagagt 1550

 aaatgtatta gaaatacagt atccagactg ctagtccttg ccagagacat 1600

 tcttacctct gccctgtgat aatattttat gcttgacagt gaaaacaagt 1650

 gtggcccctt gcaccggtta gctagaagta cagccagatt tcaagctagt 1700

 gcagtcacct cttccgtcat tcttcacaaa tcttgtcaac ctggatctta 1750

 gacttcatct gaatcgagtt ctttgccctc ctttgtgcct gcagctcata 1800

 tggaggtctt tgccaccaat gggagatgag cccaaacttt cgatctaggt 1850

 gggtgatgtg tagcagttca agggaagggt gctgtgtttt catagcatgg 1900

 agtcggagga gagggccatt tagcaggggg agcagaagag gcaattcctc 1950

 ctgggctagg ggttgtcaat gaggtttcaa cattttgtta gctgtgtgca 2000

 gcattcccag agcttcagtc tctgtgcata ctcagctttg tagaaccatg 2050

 ctgcaaagcc atataccgat ggggttatcc atgcaactat ctccattcct 2100

 acaatgtcct taatatgaga tcatcaaaca ttgatagtag ggactccatg 2150

 gaatatttgc ccagtaatgg taagaaatct ttcgggtaag agtatggatg 2200

 gttcttcttt tacccaatct gcttatagct ttttttgtaa acagggaaat 2250

 gttgagtggt acttgtattc ccttatcaaa ttaatcacat agcttttata 2300

 cagaaactct tcctgtgtga gctgttaagg tgccaaattg gctgtcattt 2350

 gtattcatga cacataccat aaagcatctg ctaatgcttt aatggattga 2400

 ttcaattaag acctgagtga cactatttgt aaatataact agttgtgaag 2450

 cacacatacc tttattttgg gaatttatga gaaaatatag aaaaccacag 2500

 atcagggatt catatatgta gctcaaaaat tcccaaaagt ttactgttag 2550

 agttggcaat ttcctatcac tatttcagtg tcagaacaaa ctgaaaataa 2600

 tggctcgtgt ttatgttgaa gataaatagc accattattg ggggaagtta 2650

 ttcaaaagca ggcttttgag caccatagtc taaatgccaa taaaaataat 2700

 tcatacatag aaatgtcatt ggtcctgaat ttgaagaaag tgagcaacag 2750

 tagttaaatg tgggtgcata taaccaaatt ccccttcatc aagaatggag 2800

 gagaagagag aagaatgaaa tcctgaagat tcatcccagc cgcaactcag 2850

 gatccaacac aactttaact gggaggaata cattgtttga tcatttttaa 2900

 aacatctgtg aatgagtgat tccggaggcc tgtgaattgt gtggggagct 2950

 tgctttgatg gcactgtgtt aataaaagtt gtagggactg tgcacctaag 3000

 aggctaagag gtcccactca tccgccctgt gaaccagctg taaagaaatg 3050

 tagttaagaa atgcaaagaa atgtgttatc ttggcacttg ggtttgattt 3100

 tccttttttt aaagcactgc aaaacttctt taggatacta aaacatccta 3150

 attgggctgt ttttttgttt tgttttgttt ttcagctaaa ggcaaagata 3200

 attttttttt cagctgaagt ttttcttttt tgcaactatg acatgaattg 3250

 agtgataaaa tggctctttg aaaagtagat attgtctgta ttgtaaatgc 3300

 ttagtcatat tcatggcaaa gtgttcattt cttgagatgg ttctttcaca 3350

 acacacaaga atcaagatgg aacgcaagga aaatcttttt gttttgaccg 3400

 aggtaaccag tttatgtgtg ttccaatcca tagagaagtg ggggaaaggg 3450

 cgagaaagga tcagattgat ctgggatcag ctttgagcct gagttcagtg 3500

 aatagcctca tgggcatctc atggaattga tgcatttgct gtggcatatt 3550

 taaattttgt tcaaaagatt tgaagcaaga ccttgcaaag actcttaaca 3600

 ttactgttca gcttgcttag attgtgttaa cagttcattt aacaaagatc 3650

 cgttttaact ctgaacaaaa gcaacccaga gcggccattc tctattccca 3700

 tgctggtcaa tacgctttca ttaccaattg gcccttacca aacttttctt 3750

 atatatatat ttgtatttta ctatgatagt tgagaaattt agcctcttag 3800

 tcatttttag ctgttattgt ggaagacctc aaatacaaga ttagatgccc 3850

 ttgaacatgt tttaatgatg tgtgtcatgt tactatcaat ggtgatttca 3900

 atcgcaatat tttaaattga tgagaatgat ttgtaaacat gaagttacta 3950

 ttacgtaaat tctgtttgtt atagagtttc ttcagttgtt acccaagtgt 4000

 catcctagag aagtcagaag aatcagaatc catcgtattt tagagttatg 4050

 tgaatctaca tcataaatgg gcattaacat tctaaattgc ttggtttgga 4100

 gaatgtgtta gcagcatagc tatattcaac tagggagatg ctaaatacac 4150

 agaagtttca agagccttgg aacagaatta caggggaact atatatgtat 4200

 atgtatattt tattaaacac ccatctgcac tatcagtatt gcactaatgt 4250

 ggaatttgaa agactatttt gctgatactg tatatatgcg catcattcct 4300

 gattagattg ttgtaaagac aatctgaaag atctaaggtt ttaaaataat 4350

 ttggtttgaa aatatacagt tgtcttgaag gaattgctgt catacatgaa 4400

 gttgctccga gctgtcttta ttctcttctt ggtcaaggtt aacaattgct 4450

 aaatgatcgc aaattcacct aaacaataca tttacaaagc catctttaca 4500

 tgcattaaac gagggctaca acaatattgt tttacaaata ctagcacttt 4550

 tttttctgtt atgtacttag tgttagaggg tcaaaataat ctttctgctt 4600

 agcatctctt aaaccatacc tgcaaatata gcaggattat tacatttaca 4650

 gtactttaat acttgtataa actatgcaga aatttttaat aaagtgtaat 4700

 atattttata agctaataag actgaatggg taaaggtttt tagcatgcgt 4750

 tagtatactt gcagatactg aaacattttg gtaatctttc ttactaaaga 4800

 tgtgaatgtt taatgtacct tctctgtttc tactctgtag tccaatggga 4850

 attcagtaat gacattttgt catgtcaaac tgtgaacata aatttgtact 4900

 gtacagtcct catatactat atacagtatg caatatatat tatatacttg 4950

 ttaataaaac catcagaata ttaaaaaaaa tctatgtcgg gtgcggagaa 5000

 agaggtaatg aaatggcagg aattcgatat cagc 5034

<210> 4133
<211> 345
<212> PRT
<213> Homo sapien

<400> 4133
 Met Leu Met Phe Asp Pro Val Pro Val Lys Gln Glu Ala Met Asp
   1               5                  10                  15

 Pro Val Ser Val Ser Tyr Pro Ser Asn Tyr Met Glu Ser Met Lys
                  20                  25                  30

 Pro Asn Lys Tyr Gly Val Ile Tyr Ser Thr Pro Leu Pro Glu Lys
                  35                  40                  45

 Phe Phe Gln Thr Pro Glu Gly Leu Ser His Gly Ile Gln Met Glu
                  50                  55                  60

 Pro Val Asp Leu Thr Val Asn Lys Arg Ser Ser Pro Pro Ser Ala
                  65                  70                  75

 Gly Asn Ser Pro Ser Ser Leu Lys Phe Pro Ser Ser His Arg Arg
                  80                  85                  90

 Ala Ser Pro Gly Leu Ser Met Pro Ser Ser Ser Pro Pro Ile Lys
                  95                 100                 105

 Lys Tyr Ser Pro Pro Ser Pro Gly Val Gln Pro Phe Gly Val Pro
                 110                 115                 120

 Leu Ser Met Pro Pro Val Met Ala Ala Ala Leu Ser Arg His Gly
                 125                 130                 135

 Ile Arg Ser Pro Gly Ile Leu Pro Val Ile Gln Pro Val Val Val
                 140                 145                 150

 Gln Pro Val Pro Phe Met Tyr Thr Ser His Leu Gln Gln Pro Leu
                 155                 160                 165

 Met Val Ser Leu Ser Glu Glu Met Glu Asn Ser Ser Ser Ser Met
                 170                 175                 180

 Gln Val Pro Val Ile Glu Ser Tyr Glu Lys Pro Ile Ser Gln Lys
                 185                 190                 195

 Lys Ile Lys Ile Glu Pro Gly Ile Glu Pro Gln Arg Thr Asp Tyr
                 200                 205                 210

 Tyr Pro Glu Glu Met Ser Pro Pro Leu Met Asn Ser Val Ser Pro
                 215                 220                 225

 Pro Gln Ala Leu Leu Gln Glu Asn His Pro Ser Val Ile Val Gln
                 230                 235                 240

 Pro Gly Lys Arg Pro Leu Pro Val Glu Ser Pro Asp Thr Gln Arg
                 245                 250                 255

 Lys Arg Arg Ile His Arg Cys Asp Tyr Asp Gly Cys Asn Lys Val
                 260                 265                 270

 Tyr Thr Lys Ser Ser His Leu Lys Ala His Arg Arg Thr His Thr
                 275                 280                 285

 Gly Glu Lys Pro Tyr Lys Cys Thr Trp Glu Gly Cys Thr Trp Lys
                 290                 295                 300

 Phe Ala Arg Ser Asp Glu Leu Thr Arg His Phe Arg Lys His Thr
                 305                 310                 315

 Gly Ile Lys Pro Phe Gln Cys Pro Asp Cys Asp Arg Ser Phe Ser
                 320                 325                 330

 Arg Ser Asp His Leu Ala Leu His Arg Lys Arg His Met Leu Val
                 335                 340                 345

<210> 4134
<211> 952
<212> DNA
<213> Homo sapien

<400> 4134
 ccacgcgtcc ggcacttccg cccatccccc tccggatccc tctgttcggg 50

 ctcgggtttc cgccgagacg acagggactg ccaggtcgga agtagtgtga 100

 ggctcgtggg cggagccaag cgccgccatg tccgccgccc tgctgcggcg 150

 gggcctggag ctgctggcgg cgtccgaggc cccccgggac cctccaggtc 200

 aggccaagcc gagaggggct ccggtgaaac ggccccggaa gacgaaggca 250

 attcaggccc agaaactgcg gaactcggcc aagggaaagg tgcccaagtc 300

 ggcactggac gagtaccgga agcgagagtg tcgagaccac ctcagagtaa 350

 acctgaagtt tctgaccagg acgagaagca ccgtggctga gtctgtgagc 400

 cagcagattt tgcgccagaa ccggggccgc aaggcctgtg accggcctgt 450

 ggccaagacc aagaagaaga aggctgaggg caccgtgttc accgaggaag 500

 acttccagaa gttccagcag gaatacttcg gcagctaggc tccctggagg 550

 gcacggtgaa gaggccttca agccctgcag cctccgactc ctgctggctc 600

 caggaaccgg ccgtgccgcg cggccagcag atggcgatgc aggaccagcc 650

 tggctcgagg aagccgcgga gctgagccga gtggaggctg gaatggagct 700

 ggtgggccgg aagtcctggg gaggatttac acacagaccg gagctggctt 750

 ccgcaggcct gggcagagca tctgcacctg ccggaaagga acgtatctgt 800

 tttgtttgct tttgcccagg tggggcctct gggctgtttg ctgtggagca 850

 aggctaattc ctgagccctt ggggacgaca gctccaggag taggaagaag 900

 ggtgggcttc caagttacaa taaatgtgaa cccaagaaaa aaaaaaaaaa 950

 aa 952

<210> 4135
<211> 129
<212> PRT
<213> Homo sapien

<400> 4135
 Pro Arg Val Arg His Phe Arg Pro Ser Pro Ser Gly Ser Leu Cys
   1               5                  10                  15

 Ser Gly Ser Gly Phe Arg Arg Asp Asp Arg Asp Cys Gln Val Gly
                  20                  25                  30

 Ser Ser Val Arg Leu Val Gly Gly Ala Lys Arg Arg His Val Arg
                  35                  40                  45

 Arg Pro Ala Ala Ala Gly Pro Gly Ala Ala Gly Gly Val Arg Gly
                  50                  55                  60

 Pro Pro Gly Pro Ser Arg Ser Gly Gln Ala Glu Arg Gly Ser Gly
                  65                  70                  75

 Glu Thr Ala Pro Glu Asp Glu Gly Asn Ser Gly Pro Glu Thr Ala
                  80                  85                  90

 Glu Leu Gly Gln Gly Lys Gly Ala Gln Val Gly Thr Gly Arg Val
                  95                 100                 105

 Pro Glu Ala Arg Val Ser Arg Pro Pro Gln Ser Lys Pro Glu Val
                 110                 115                 120

 Ser Asp Gln Asp Glu Lys His Arg Gly
                 125

<210> 4136
<211> 3468
<212> DNA
<213> Homo sapien

<400> 4136
 ctcttacaac attggctgcc ggcgtgactt tgaccgcttc ccggtgcgtt 50

 accggcagct gaacccaccc ggcgccacgg gactttgacg cgtgctctgc 100

 gcttgccatg agactcctgg gagctgcagc cgtcgcggct ctggggcgcg 150

 gaagggcccc cgcctcccta ggctggcaga ggaagcaggt taattggaag 200

 gcctgccgat ggtcttcatc aggggtgatt cctaatgaaa aaatacgaaa 250

 tattggaatc tcagctcaca ttgattctgg gaaaactaca ttaacagaac 300

 gagtccttta ctacactggc agaattgcaa agatgcatga ggtgaaaggt 350

 aaagatggag ttggtgctgt catggattcc atggaactag agagacaaag 400

 aggaatcact attcagtcag cagccactta caccatgtgg aaagatgtca 450

 atattaacat tatagatact cctgggcatg tggacttcac aatagaagtg 500

 gaaagggccc tgagagtgtt ggatggtgca gtccttgttc tctgtgctgt 550

 tggaggggta cagtgccaga ccatgactgt caatcgtcag atgaagcgct 600

 acaacgttcc gtttctaact tttattaaca aattggaccg aatgggctcc 650

 aacccagcca gggccctgca gcaaatgagg tctaaactaa atcataatgc 700

 agcgtttatg cagataccca tgggtttgga gggtaatttt aaaggtattg 750

 tagatcttat tgaggaacga gccatctatt ttgatggaga ctttggtcag 800

 attgttcgat atggtgagat tccagctgaa ttaagggcgg cggccactga 850

 ccaccggcag gagctaattg aatgtgttgc caattcagat gaacagcttg 900

 gtgagatgtt tctggaagaa aaaatcccct cgatttctga tttaaagcta 950

 gcaattcgaa gagctactct gaaaagatca tttactcctg tatttttggg 1000

 aagcgccttg aagaacaaag gagttcagcc tcttttagat gctgttttag 1050

 aatacctccc aaatccatct gaagtccaga actatgctat tctcaataaa 1100

 gaggatgact caaaagagaa aaccaaaatc ctaatgaact ccagtagaga 1150

 caattcccac ccatttgtag gcctggcttt taaactggag gtaggtcgat 1200

 ttggacaatt aacttatgtt cgcagttatc agggagagct aaagaagggt 1250

 gacaccatct ataacacaag gacaagaaag aaagtacggt tgcaacggct 1300

 ggctcgcatg catgccgaca tgatggagga tgttgaggaa gtatatgccg 1350

 gagacatctg tgcattgttt ggcattgact gtgctagtgg agacacattc 1400

 acagacaaag ccaacagcgg cctttctatg gagtcaattc atgttcctga 1450

 tcctgtcatt tcaatagcaa tgaagccttc taacaagaac gatctggaaa 1500

 aattttcaaa aggtattggc aggtttacaa gagaagatcc cacatttaaa 1550

 gtatactttg acactgagaa caaagagaca gttatatctg gaatgggaga 1600

 attacacctg gaaatctatg ctcagaggct ggaaagagag tatggctgtc 1650

 cttgtatcac aggaaagcca aaagttgcct ttcgagagac cattactgcc 1700

 cctgtcccgt ttgactttac acataaaaaa caatcaggtg gtgcaggcca 1750

 gtatggaaaa gtaataggtg tcctggagcc tctggaccca gaggactaca 1800

 ctaaattgga attttcagat gaaacattcg gatcaaatat tccaaagcag 1850

 tttgtgcctg ctgtagaaaa ggggttttta gatgcctgcg agaagggccc 1900

 tctttctggt cacaagctct ctgggctccg gtttgtcctg caagatggag 1950

 cacaccacat ggttgattct aatgaaatct ctttcatccg agcaggagaa 2000

 ggtgctctta aacaagcctt ggcaaatgca acattatgta ttcttgaacc 2050

 tattatggct gtggaagttg tagctccaaa tgaatttcag ggacaagtaa 2100

 ttgcaggaat taaccgacgc catggggtaa tcactgggca agatggagtt 2150

 gaggactatt ttacactgta tgcagatgtc cctctaaatg atatgtttgg 2200

 ttattccact gaacttaggt catgcacaga gggaaaggga gaatacacaa 2250

 tggagtatag caggtatcag ccatgtttac catccacaca agaagacgtc 2300

 attaataagt atttggaagc tacaggtcaa cttcctgtta aaaaaggaaa 2350

 agccaagaac taactttgct tactgtgagt tgactgactc taattgaatc 2400

 tgcgtggttt tgatactttg atggattcca gtggaataaa ttcaggctgc 2450

 tgaaacaaga aattctgagc ccaggaagcg ggctcttctt tcttcaaaag 2500

 aagcccttct tgttcatatt caggagcttc tgttatattc aaaggtaatt 2550

 ctatgtctat ctcaactcta ttgattggtt ttatagttca ttgaaaatcc 2600

 tcaaataaaa tataattatt actgaaatat gtttaatatt taaggggaaa 2650

 agagactaat ttcagttata cttttaagct tagaatgtat gttcatttcc 2700

 aaattttgta tcataagagt tttcaacata gagaaaagct gaaaaaatgc 2750

 aaagaataac cacatacttt ccatctacct tcctttgtta acgggttgtt 2800

 tatcatataa taatttgttt tgtcatattt gctttcactg tctattatct 2850

 gtttaagtct cataactcta tttttagttt gctgaagact tgaaagtgaa 2900

 tcgcatatat catgacactt cttggagtgt cattaatggg caggcttttc 2950

 tgttgaagag tggattccgt atgttcttca tagagagtgt ttttcagatt 3000

 cttcattggg atattaaaat attagccaaa tttctctctg ttttatatat 3050

 gtctgtttat ttcagtttgt ggtttctgca aatttgtaac tgcctctgtt 3100

 ttaggagtat aagtattact tccttgtggt ctattgtgaa gtaaaaagta 3150

 gacccttgca tatactattc ttgtttgtgt tcatcttaat gtttttgtac 3200

 agctaaatca aatgtaattt atagagttag tttcatcaac ctaatgaatg 3250

 ctagttaaat ttgaattcct tggaatttat cgtatattgt attcactgag 3300

 attatgaagg gacaaatgtt aatcttttgt ttccagaaaa agttgggctt 3350

 tcccaagcag ttctattacc cggttcagaa ttgcttcatc caaaaatcat 3400

 ctgatggtat agatggatcc tagtcctttt cattacctga tggtagaaat 3450

 aaaataattg attttaaa 3468

<210> 4137
<211> 751
<212> PRT
<213> Homo sapien

<400> 4137
 Met Arg Leu Leu Gly Ala Ala Ala Val Ala Ala Leu Gly Arg Gly
   1               5                  10                  15

 Arg Ala Pro Ala Ser Leu Gly Trp Gln Arg Lys Gln Val Asn Trp
                  20                  25                  30

 Lys Ala Cys Arg Trp Ser Ser Ser Gly Val Ile Pro Asn Glu Lys
                  35                  40                  45

 Ile Arg Asn Ile Gly Ile Ser Ala His Ile Asp Ser Gly Lys Thr
                  50                  55                  60

 Thr Leu Thr Glu Arg Val Leu Tyr Tyr Thr Gly Arg Ile Ala Lys
                  65                  70                  75

 Met His Glu Val Lys Gly Lys Asp Gly Val Gly Ala Val Met Asp
                  80                  85                  90

 Ser Met Glu Leu Glu Arg Gln Arg Gly Ile Thr Ile Gln Ser Ala
                  95                 100                 105

 Ala Thr Tyr Thr Met Trp Lys Asp Val Asn Ile Asn Ile Ile Asp
                 110                 115                 120

 Thr Pro Gly His Val Asp Phe Thr Ile Glu Val Glu Arg Ala Leu
                 125                 130                 135

 Arg Val Leu Asp Gly Ala Val Leu Val Leu Cys Ala Val Gly Gly
                 140                 145                 150

 Val Gln Cys Gln Thr Met Thr Val Asn Arg Gln Met Lys Arg Tyr
                 155                 160                 165

 Asn Val Pro Phe Leu Thr Phe Ile Asn Lys Leu Asp Arg Met Gly
                 170                 175                 180

 Ser Asn Pro Ala Arg Ala Leu Gln Gln Met Arg Ser Lys Leu Asn
                 185                 190                 195

 His Asn Ala Ala Phe Met Gln Ile Pro Met Gly Leu Glu Gly Asn
                 200                 205                 210

 Phe Lys Gly Ile Val Asp Leu Ile Glu Glu Arg Ala Ile Tyr Phe
                 215                 220                 225

 Asp Gly Asp Phe Gly Gln Ile Val Arg Tyr Gly Glu Ile Pro Ala
                 230                 235                 240

 Glu Leu Arg Ala Ala Ala Thr Asp His Arg Gln Glu Leu Ile Glu
                 245                 250                 255

 Cys Val Ala Asn Ser Asp Glu Gln Leu Gly Glu Met Phe Leu Glu
                 260                 265                 270

 Glu Lys Ile Pro Ser Ile Ser Asp Leu Lys Leu Ala Ile Arg Arg
                 275                 280                 285

 Ala Thr Leu Lys Arg Ser Phe Thr Pro Val Phe Leu Gly Ser Ala
                 290                 295                 300

 Leu Lys Asn Lys Gly Val Gln Pro Leu Leu Asp Ala Val Leu Glu
                 305                 310                 315

 Tyr Leu Pro Asn Pro Ser Glu Val Gln Asn Tyr Ala Ile Leu Asn
                 320                 325                 330

 Lys Glu Asp Asp Ser Lys Glu Lys Thr Lys Ile Leu Met Asn Ser
                 335                 340                 345

 Ser Arg Asp Asn Ser His Pro Phe Val Gly Leu Ala Phe Lys Leu
                 350                 355                 360

 Glu Val Gly Arg Phe Gly Gln Leu Thr Tyr Val Arg Ser Tyr Gln
                 365                 370                 375

 Gly Glu Leu Lys Lys Gly Asp Thr Ile Tyr Asn Thr Arg Thr Arg
                 380                 385                 390

 Lys Lys Val Arg Leu Gln Arg Leu Ala Arg Met His Ala Asp Met
                 395                 400                 405

 Met Glu Asp Val Glu Glu Val Tyr Ala Gly Asp Ile Cys Ala Leu
                 410                 415                 420

 Phe Gly Ile Asp Cys Ala Ser Gly Asp Thr Phe Thr Asp Lys Ala
                 425                 430                 435

 Asn Ser Gly Leu Ser Met Glu Ser Ile His Val Pro Asp Pro Val
                 440                 445                 450

 Ile Ser Ile Ala Met Lys Pro Ser Asn Lys Asn Asp Leu Glu Lys
                 455                 460                 465

 Phe Ser Lys Gly Ile Gly Arg Phe Thr Arg Glu Asp Pro Thr Phe
                 470                 475                 480

 Lys Val Tyr Phe Asp Thr Glu Asn Lys Glu Thr Val Ile Ser Gly
                 485                 490                 495

 Met Gly Glu Leu His Leu Glu Ile Tyr Ala Gln Arg Leu Glu Arg
                 500                 505                 510

 Glu Tyr Gly Cys Pro Cys Ile Thr Gly Lys Pro Lys Val Ala Phe
                 515                 520                 525

 Arg Glu Thr Ile Thr Ala Pro Val Pro Phe Asp Phe Thr His Lys
                 530                 535                 540

 Lys Gln Ser Gly Gly Ala Gly Gln Tyr Gly Lys Val Ile Gly Val
                 545                 550                 555

 Leu Glu Pro Leu Asp Pro Glu Asp Tyr Thr Lys Leu Glu Phe Ser
                 560                 565                 570

 Asp Glu Thr Phe Gly Ser Asn Ile Pro Lys Gln Phe Val Pro Ala
                 575                 580                 585

 Val Glu Lys Gly Phe Leu Asp Ala Cys Glu Lys Gly Pro Leu Ser
                 590                 595                 600

 Gly His Lys Leu Ser Gly Leu Arg Phe Val Leu Gln Asp Gly Ala
                 605                 610                 615

 His His Met Val Asp Ser Asn Glu Ile Ser Phe Ile Arg Ala Gly
                 620                 625                 630

 Glu Gly Ala Leu Lys Gln Ala Leu Ala Asn Ala Thr Leu Cys Ile
                 635                 640                 645

 Leu Glu Pro Ile Met Ala Val Glu Val Val Ala Pro Asn Glu Phe
                 650                 655                 660

 Gln Gly Gln Val Ile Ala Gly Ile Asn Arg Arg His Gly Val Ile
                 665                 670                 675

 Thr Gly Gln Asp Gly Val Glu Asp Tyr Phe Thr Leu Tyr Ala Asp
                 680                 685                 690

 Val Pro Leu Asn Asp Met Phe Gly Tyr Ser Thr Glu Leu Arg Ser
                 695                 700                 705

 Cys Thr Glu Gly Lys Gly Glu Tyr Thr Met Glu Tyr Ser Arg Tyr
                 710                 715                 720

 Gln Pro Cys Leu Pro Ser Thr Gln Glu Asp Val Ile Asn Lys Tyr
                 725                 730                 735

 Leu Glu Ala Thr Gly Gln Leu Pro Val Lys Lys Gly Lys Ala Lys
                 740                 745                 750

 Asn


<210> 4138
<211> 3468
<212> DNA
<213> Homo sapien

<400> 4138
 ctcttacaac attggctgcc ggcgtgactt tgaccgcttc ccggtgcgtt 50

 accggcagct gaacccaccc ggcgccacgg gactttgacg cgtgctctgc 100

 gcttgccatg agactcctgg gagctgcagc cgtcgcggct ctggggcgcg 150

 gaagggcccc cgcctcccta ggctggcaga ggaagcaggt taattggaag 200

 gcctgccgat ggtcttcatc aggggtgatt cctaatgaaa aaatacgaaa 250

 tattggaatc tcagctcaca ttgattctgg gaaaactaca ttaacagaac 300

 gagtccttta ctacactggc agaattgcaa agatgcatga ggtgaaaggt 350

 aaagatggag ttggtgctgt catggattcc atggaactag agagacaaag 400

 aggaatcact attcagtcag cagccactta caccatgtgg aaagatgtca 450

 atattaacat tatagatact cctgggcatg tggacttcac aatagaagtg 500

 gaaagggccc tgagagtgtt ggatggtgca gtccttgttc tctgtgctgt 550

 tggaggggta cagtgccaga ccatgactgt caatcgtcag atgaagcgct 600

 acaacgttcc gtttctaact tttattaaca aattggaccg aatgggctcc 650

 aacccagcca gggccctgca gcaaatgagg tctaaactaa atcataatgc 700

 agcgtttatg cagataccca tgggtttgga gggtaatttt aaaggtattg 750

 tagatcttat tgaggaacga gccatctatt ttgatggaga ctttggtcag 800

 attgttcgat atggtgagat tccagctgaa ttaagggcgg cggccactga 850

 ccaccggcag gagctaattg aatgtgttgc caattcagat gaacagcttg 900

 gtgagatgtt tctggaagaa aaaatcccct cgatttctga tttaaagcta 950

 gcaattcgaa gagctactct gaaaagatca tttactcctg tatttttggg 1000

 aagcgccttg aagaacaaag gagttcagcc tcttttagat gctgttttag 1050

 aatacctccc aaatccatct gaagtccaga actatgctat tctcaataaa 1100

 gaggatgact caaaagagaa aaccaaaatc ctaatgaact ccagtagaga 1150

 caattcccac ccatttgtag gcctggcttt taaactggag gtaggtcgat 1200

 ttggacaatt aacttatgtt cgcagttatc agggagagct aaagaagggt 1250

 gacaccatct ataacacaag gacaagaaag aaagtacggt tgcaacggct 1300

 ggctcgcatg catgccgaca tgatggagga tgttgaggaa gtatatgccg 1350

 gagacatctg tgcattgttt ggcattgact gtgctagtgg agacacattc 1400

 acagacaaag ccaacagcgg cctttctatg gagtcaattc atgttcctga 1450

 tcctgtcatt tcaatagcaa tgaagccttc taacaagaac gatctggaaa 1500

 aattttcaaa aggtattggc aggtttacaa gagaagatcc cacatttaaa 1550

 gtatactttg acactgagaa caaagagaca gttatatctg gaatgggaga 1600

 attacacctg gaaatctatg ctcagaggct ggaaagagag tatggctgtc 1650

 cttgtatcac aggaaagcca aaagttgcct ttcgagagac cattactgcc 1700

 cctgtcccgt ttgactttac acataaaaaa caatcaggtg gtgcaggcca 1750

 gtatggaaaa gtaataggtg tcctggagcc tctggaccca gaggactaca 1800

 ctaaattgga attttcagat gaaacattcg gatcaaatat tccaaagcag 1850

 tttgtgcctg ctgtagaaaa ggggttttta gatgcctgcg agaagggccc 1900

 tctttctggt cacaagctct ctgggctccg gtttgtcctg caagatggag 1950

 cacaccacat ggttgattct aatgaaatct ctttcatccg agcaggagaa 2000

 ggtgctctta aacaagcctt ggcaaatgca acattatgta ttcttgaacc 2050

 tattatggct gtggaagttg tagctccaaa tgaatttcag ggacaagtaa 2100

 ttgcaggaat taaccgacgc catggggtaa tcactgggca agatggagtt 2150

 gaggactatt ttacactgta tgcagatgtc cctctaaatg atatgtttgg 2200

 ttattccact gaacttaggt catgcacaga gggaaaggga gaatacacaa 2250

 tggagtatag caggtatcag ccatgtttac catccacaca agaagacgtc 2300

 attaataagt atttggaagc tacaggtcaa cttcctgtta aaaaaggaaa 2350

 agccaagaac taactttgct tactgtgagt tgactgactc taattgaatc 2400

 tgcgtggttt tgatactttg atggattcca gtggaataaa ttcaggctgc 2450

 tgaaacaaga aattctgagc ccaggaagcg ggctcttctt tcttcaaaag 2500

 aagcccttct tgttcatatt caggagcttc tgttatattc aaaggtaatt 2550

 ctatgtctat ctcaactcta ttgattggtt ttatagttca ttgaaaatcc 2600

 tcaaataaaa tataattatt actgaaatat gtttaatatt taaggggaaa 2650

 agagactaat ttcagttata cttttaagct tagaatgtat gttcatttcc 2700

 aaattttgta tcataagagt tttcaacata gagaaaagct gaaaaaatgc 2750

 aaagaataac cacatacttt ccatctacct tcctttgtta acgggttgtt 2800

 tatcatataa taatttgttt tgtcatattt gctttcactg tctattatct 2850

 gtttaagtct cataactcta tttttagttt gctgaagact tgaaagtgaa 2900

 tcgcatatat catgacactt cttggagtgt cattaatggg caggcttttc 2950

 tgttgaagag tggattccgt atgttcttca tagagagtgt ttttcagatt 3000

 cttcattggg atattaaaat attagccaaa tttctctctg ttttatatat 3050

 gtctgtttat ttcagtttgt ggtttctgca aatttgtaac tgcctctgtt 3100

 ttaggagtat aagtattact tccttgtggt ctattgtgaa gtaaaaagta 3150

 gacccttgca tatactattc ttgtttgtgt tcatcttaat gtttttgtac 3200

 agctaaatca aatgtaattt atagagttag tttcatcaac ctaatgaatg 3250

 ctagttaaat ttgaattcct tggaatttat cgtatattgt attcactgag 3300

 attatgaagg gacaaatgtt aatcttttgt ttccagaaaa agttgggctt 3350

 tcccaagcag ttctattacc cggttcagaa ttgcttcatc caaaaatcat 3400

 ctgatggtat agatggatcc tagtcctttt cattacctga tggtagaaat 3450

 aaaataattg attttaaa 3468

<210> 4139
<211> 751
<212> PRT
<213> Homo sapien

<400> 4139
 Met Arg Leu Leu Gly Ala Ala Ala Val Ala Ala Leu Gly Arg Gly
   1               5                  10                  15

 Arg Ala Pro Ala Ser Leu Gly Trp Gln Arg Lys Gln Val Asn Trp
                  20                  25                  30

 Lys Ala Cys Arg Trp Ser Ser Ser Gly Val Ile Pro Asn Glu Lys
                  35                  40                  45

 Ile Arg Asn Ile Gly Ile Ser Ala His Ile Asp Ser Gly Lys Thr
                  50                  55                  60

 Thr Leu Thr Glu Arg Val Leu Tyr Tyr Thr Gly Arg Ile Ala Lys
                  65                  70                  75

 Met His Glu Val Lys Gly Lys Asp Gly Val Gly Ala Val Met Asp
                  80                  85                  90

 Ser Met Glu Leu Glu Arg Gln Arg Gly Ile Thr Ile Gln Ser Ala
                  95                 100                 105

 Ala Thr Tyr Thr Met Trp Lys Asp Val Asn Ile Asn Ile Ile Asp
                 110                 115                 120

 Thr Pro Gly His Val Asp Phe Thr Ile Glu Val Glu Arg Ala Leu
                 125                 130                 135

 Arg Val Leu Asp Gly Ala Val Leu Val Leu Cys Ala Val Gly Gly
                 140                 145                 150

 Val Gln Cys Gln Thr Met Thr Val Asn Arg Gln Met Lys Arg Tyr
                 155                 160                 165

 Asn Val Pro Phe Leu Thr Phe Ile Asn Lys Leu Asp Arg Met Gly
                 170                 175                 180

 Ser Asn Pro Ala Arg Ala Leu Gln Gln Met Arg Ser Lys Leu Asn
                 185                 190                 195

 His Asn Ala Ala Phe Met Gln Ile Pro Met Gly Leu Glu Gly Asn
                 200                 205                 210

 Phe Lys Gly Ile Val Asp Leu Ile Glu Glu Arg Ala Ile Tyr Phe
                 215                 220                 225

 Asp Gly Asp Phe Gly Gln Ile Val Arg Tyr Gly Glu Ile Pro Ala
                 230                 235                 240

 Glu Leu Arg Ala Ala Ala Thr Asp His Arg Gln Glu Leu Ile Glu
                 245                 250                 255

 Cys Val Ala Asn Ser Asp Glu Gln Leu Gly Glu Met Phe Leu Glu
                 260                 265                 270

 Glu Lys Ile Pro Ser Ile Ser Asp Leu Lys Leu Ala Ile Arg Arg
                 275                 280                 285

 Ala Thr Leu Lys Arg Ser Phe Thr Pro Val Phe Leu Gly Ser Ala
                 290                 295                 300

 Leu Lys Asn Lys Gly Val Gln Pro Leu Leu Asp Ala Val Leu Glu
                 305                 310                 315

 Tyr Leu Pro Asn Pro Ser Glu Val Gln Asn Tyr Ala Ile Leu Asn
                 320                 325                 330

 Lys Glu Asp Asp Ser Lys Glu Lys Thr Lys Ile Leu Met Asn Ser
                 335                 340                 345

 Ser Arg Asp Asn Ser His Pro Phe Val Gly Leu Ala Phe Lys Leu
                 350                 355                 360

 Glu Val Gly Arg Phe Gly Gln Leu Thr Tyr Val Arg Ser Tyr Gln
                 365                 370                 375

 Gly Glu Leu Lys Lys Gly Asp Thr Ile Tyr Asn Thr Arg Thr Arg
                 380                 385                 390

 Lys Lys Val Arg Leu Gln Arg Leu Ala Arg Met His Ala Asp Met
                 395                 400                 405

 Met Glu Asp Val Glu Glu Val Tyr Ala Gly Asp Ile Cys Ala Leu
                 410                 415                 420

 Phe Gly Ile Asp Cys Ala Ser Gly Asp Thr Phe Thr Asp Lys Ala
                 425                 430                 435

 Asn Ser Gly Leu Ser Met Glu Ser Ile His Val Pro Asp Pro Val
                 440                 445                 450

 Ile Ser Ile Ala Met Lys Pro Ser Asn Lys Asn Asp Leu Glu Lys
                 455                 460                 465

 Phe Ser Lys Gly Ile Gly Arg Phe Thr Arg Glu Asp Pro Thr Phe
                 470                 475                 480

 Lys Val Tyr Phe Asp Thr Glu Asn Lys Glu Thr Val Ile Ser Gly
                 485                 490                 495

 Met Gly Glu Leu His Leu Glu Ile Tyr Ala Gln Arg Leu Glu Arg
                 500                 505                 510

 Glu Tyr Gly Cys Pro Cys Ile Thr Gly Lys Pro Lys Val Ala Phe
                 515                 520                 525

 Arg Glu Thr Ile Thr Ala Pro Val Pro Phe Asp Phe Thr His Lys
                 530                 535                 540

 Lys Gln Ser Gly Gly Ala Gly Gln Tyr Gly Lys Val Ile Gly Val
                 545                 550                 555

 Leu Glu Pro Leu Asp Pro Glu Asp Tyr Thr Lys Leu Glu Phe Ser
                 560                 565                 570

 Asp Glu Thr Phe Gly Ser Asn Ile Pro Lys Gln Phe Val Pro Ala
                 575                 580                 585

 Val Glu Lys Gly Phe Leu Asp Ala Cys Glu Lys Gly Pro Leu Ser
                 590                 595                 600

 Gly His Lys Leu Ser Gly Leu Arg Phe Val Leu Gln Asp Gly Ala
                 605                 610                 615

 His His Met Val Asp Ser Asn Glu Ile Ser Phe Ile Arg Ala Gly
                 620                 625                 630

 Glu Gly Ala Leu Lys Gln Ala Leu Ala Asn Ala Thr Leu Cys Ile
                 635                 640                 645

 Leu Glu Pro Ile Met Ala Val Glu Val Val Ala Pro Asn Glu Phe
                 650                 655                 660

 Gln Gly Gln Val Ile Ala Gly Ile Asn Arg Arg His Gly Val Ile
                 665                 670                 675

 Thr Gly Gln Asp Gly Val Glu Asp Tyr Phe Thr Leu Tyr Ala Asp
                 680                 685                 690

 Val Pro Leu Asn Asp Met Phe Gly Tyr Ser Thr Glu Leu Arg Ser
                 695                 700                 705

 Cys Thr Glu Gly Lys Gly Glu Tyr Thr Met Glu Tyr Ser Arg Tyr
                 710                 715                 720

 Gln Pro Cys Leu Pro Ser Thr Gln Glu Asp Val Ile Asn Lys Tyr
                 725                 730                 735

 Leu Glu Ala Thr Gly Gln Leu Pro Val Lys Lys Gly Lys Ala Lys
                 740                 745                 750

 Asn


<210> 4140
<211> 3305
<212> DNA
<213> Homo sapien

<400> 4140
 tcgcagatat ggccagtaca ctatgaacca ggaaagcacc accatcaaag 50

 ttatggagaa gcctccattt gatcgatcaa tttcccagga ttctttggat 100

 gaactatcta tggaagacta ttggatagaa ctagaaaaca tcaagaaatc 150

 tagtgaaaac agccaagaag atcaagaggt ggttgttgtc aaagagcctg 200

 atgagggaga attggaagaa gagtggctta aagaggccgg tttatccaat 250

 ctcttcggag agtctgctgg agatccacag gaaagcattg tgtttttatc 300

 aacattgacg cggacccagg cagcagcagt tcagaagcga gtagagacgg 350

 tctcccagac cttgaggaaa aaaaacaaac agtaccagat tcctgacgtc 400

 agagacatat ttgctcaaca gagagaatca aaagaaacag ctccaggtgg 450

 cactgaatcg cagtcactta gaacaaatga aaacaaatac caaggaagag 500

 atgacgaggc atctaacctt gttggtgaag agaagctgat cccacctgag 550

 gagacgcctg cccctgaaac agacatcaac ctggaggtat catttgccga 600

 gcaagcactc aatcagaaag agagctccaa ggagaaaatc cagaagagca 650

 aaggcgatga tgccacatta cctagtttca gattgccaaa agacaaaacg 700

 ggtaccacaa ggattggtga cctcgcaccc caggacatga agaaagtttg 750

 ccatttagcc ctaattgagc tgactgccct ctatgatgta ttgggtattg 800

 agctgaaaca acaaaaagct gtgaaaatca aaacaaaaga ttctggtctt 850

 ttttgcgttc cattgacagc gctattagaa caagatcaga ggaaagtacc 900

 aggaatgcga atacccttga tctttcaaaa actgatttct cgaattgaag 950

 agagaggttt ggaaacagaa ggcctcttac ggatccctgg agctgccatt 1000

 agaatcaaga atctttgcca agaactagaa gcaaagtttt atgaagggac 1050

 ttttaattgg gaaagtgtca aacagcatga tgccgccagc ctgctgaagc 1100

 tcttcattcg ggagttgccc cagccactgc tcagtgtgga gtatctcaaa 1150

 gcctttcagg ctgtccagaa tcttccaacc aagaagcagc aactacaggc 1200

 tttgaacctt cttgtcatcc tcctacctga tgcaaacagg gacacactga 1250

 aggcccttct tgaatttctc caaagagtaa tagataataa agaaaaaaat 1300

 aaaatgacag tcatgaatgt agcaatggtc atggccccga atctctttat 1350

 gtgtcatgca ttgggattga agtccagtga acagcgagaa tttgtaatgg 1400

 cagctgggac agcaaatacc atgcacttat tgattaagta ccaaaaactt 1450

 ctgtggacaa ttcccaagtt tattgtaaac caagtgagga agcaaaacac 1500

 ggaaaatcat aaaaaggata aaagagccat gaagaaattg ctgaagaaaa 1550

 tggcttatga ccgagaaaaa tatgaaaagc aagataagag tacaaatgat 1600

 gctgacgttc ctcagggagt gattcgagtg caagctcccc atctttcgaa 1650

 agtttccatg gcaatacagc taactgaaga actaaaagcc agtgatgtac 1700

 ttgccaggtt tctcagccaa gaaagtgggg ttgcccagac tctcaagaaa 1750

 ggagaagttt ttttgtatga aattggagga aatattgggg aacgctgcct 1800

 tgatgatgac acttacatga aggatttata tcagcttaac ccaaatgctg 1850

 agtgggttat aaagtcaaag ccattgtaga agacttaaca agctgcagat 1900

 aaccatgtgg acttctgtca taattcttgc tgagtcaaga gtgtaaataa 1950

 aagaaatggc aggactcata ttattcagtt gtacccaagt atttaaaaat 2000

 gactctctta agccttaaaa agtcatagat ttgtgctgct gccagaatta 2050

 tattaattat tattaatgtt attattagaa aaaaaatttc tggagtgaga 2100

 gtaaagaggc ttaattagtt tgtgggcagt tttcatatgc tctgtgaaat 2150

 gtgtccagat gtgacatagt tttttttttt aatatgtgga aatgtcttct 2200

 cttcccattc ttttctccta aaatcatata tactgtaata tatgctctct 2250

 cacctctatt acctcctcac atctaccctt tcccagttag gtttgctttt 2300

 tgaccaaaaa gataacaaat accaggtatg gcaagttgtg aagacagcac 2350

 attaaaacat acctaatttc acagtattcc tgtcacgaca gaatgttagt 2400

 attcatctct ttgaatcatt tgctcaaata ataacattcc accttttcct 2450

 gctgtatcac aggaagtgat ttgcattttt tttcagttca tctgacttat 2500

 gttcacagaa ccgtatcagc gaccaagaaa ataggactgt cagaagctgc 2550

 cagttattac tgaaccatta aatacttata tactaagaat aaataaaata 2600

 tacccatgtg aaataataat tggattatgg ataacaagag agtgaaagcc 2650

 aaagcacttt ctgtctactg tactcttcta aatggaattt taaaagtcat 2700

 agctggcttt acgtgttgtc attattagca ttataaatat gcatgatagt 2750

 ataatccagt aatggttgaa gaatgtattt tacttaaaga gggatttttt 2800

 tttttaagtc ctgaataagt ctactggaag aattattctt ctgggtgaaa 2850

 aagcttttgt ttgtgttctt attttaaata atcggagtca atttattaaa 2900

 atgttcttga aagtactatt cccagggatt ttaatgcaca aaccatattg 2950

 tgacaagaga tgagcctctg tactgtaaat aagaaatgaa gtagagaaat 3000

 gttaaatatt ttatgagttt agaatatagt aaataaaagg tgatgtaaat 3050

 gaatgctgca caaacggtgt tcatgatact tttagtagta ctttaggaaa 3100

 aactacacat tctcagaagc tcttgatgtc tctaatgaag ggggggaatg 3150

 ctgttaatga gaacagtcat aaatttttag catataatta caagaacagc 3200

 ctgtggatat gatcacttaa atgattttgt ggtgattcgt gccattgctt 3250

 ttttatttaa aagaaaattt tgtaattaaa tgcctttttc taaattaaaa 3300

 aaaaa 3305

<210> 4141
<211> 618
<212> PRT
<213> Homo sapien

<400> 4141
 Met Asn Gln Glu Ser Thr Thr Ile Lys Val Met Glu Lys Pro Pro
   1               5                  10                  15

 Phe Asp Arg Ser Ile Ser Gln Asp Ser Leu Asp Glu Leu Ser Met
                  20                  25                  30

 Glu Asp Tyr Trp Ile Glu Leu Glu Asn Ile Lys Lys Ser Ser Glu
                  35                  40                  45

 Asn Ser Gln Glu Asp Gln Glu Val Val Val Val Lys Glu Pro Asp
                  50                  55                  60

 Glu Gly Glu Leu Glu Glu Glu Trp Leu Lys Glu Ala Gly Leu Ser
                  65                  70                  75

 Asn Leu Phe Gly Glu Ser Ala Gly Asp Pro Gln Glu Ser Ile Val
                  80                  85                  90

 Phe Leu Ser Thr Leu Thr Arg Thr Gln Ala Ala Ala Val Gln Lys
                  95                 100                 105

 Arg Val Glu Thr Val Ser Gln Thr Leu Arg Lys Lys Asn Lys Gln
                 110                 115                 120

 Tyr Gln Ile Pro Asp Val Arg Asp Ile Phe Ala Gln Gln Arg Glu
                 125                 130                 135

 Ser Lys Glu Thr Ala Pro Gly Gly Thr Glu Ser Gln Ser Leu Arg
                 140                 145                 150

 Thr Asn Glu Asn Lys Tyr Gln Gly Arg Asp Asp Glu Ala Ser Asn
                 155                 160                 165

 Leu Val Gly Glu Glu Lys Leu Ile Pro Pro Glu Glu Thr Pro Ala
                 170                 175                 180

 Pro Glu Thr Asp Ile Asn Leu Glu Val Ser Phe Ala Glu Gln Ala
                 185                 190                 195

 Leu Asn Gln Lys Glu Ser Ser Lys Glu Lys Ile Gln Lys Ser Lys
                 200                 205                 210

 Gly Asp Asp Ala Thr Leu Pro Ser Phe Arg Leu Pro Lys Asp Lys
                 215                 220                 225

 Thr Gly Thr Thr Arg Ile Gly Asp Leu Ala Pro Gln Asp Met Lys
                 230                 235                 240

 Lys Val Cys His Leu Ala Leu Ile Glu Leu Thr Ala Leu Tyr Asp
                 245                 250                 255

 Val Leu Gly Ile Glu Leu Lys Gln Gln Lys Ala Val Lys Ile Lys
                 260                 265                 270

 Thr Lys Asp Ser Gly Leu Phe Cys Val Pro Leu Thr Ala Leu Leu
                 275                 280                 285

 Glu Gln Asp Gln Arg Lys Val Pro Gly Met Arg Ile Pro Leu Ile
                 290                 295                 300

 Phe Gln Lys Leu Ile Ser Arg Ile Glu Glu Arg Gly Leu Glu Thr
                 305                 310                 315

 Glu Gly Leu Leu Arg Ile Pro Gly Ala Ala Ile Arg Ile Lys Asn
                 320                 325                 330

 Leu Cys Gln Glu Leu Glu Ala Lys Phe Tyr Glu Gly Thr Phe Asn
                 335                 340                 345

 Trp Glu Ser Val Lys Gln His Asp Ala Ala Ser Leu Leu Lys Leu
                 350                 355                 360

 Phe Ile Arg Glu Leu Pro Gln Pro Leu Leu Ser Val Glu Tyr Leu
                 365                 370                 375

 Lys Ala Phe Gln Ala Val Gln Asn Leu Pro Thr Lys Lys Gln Gln
                 380                 385                 390

 Leu Gln Ala Leu Asn Leu Leu Val Ile Leu Leu Pro Asp Ala Asn
                 395                 400                 405

 Arg Asp Thr Leu Lys Ala Leu Leu Glu Phe Leu Gln Arg Val Ile
                 410                 415                 420

 Asp Asn Lys Glu Lys Asn Lys Met Thr Val Met Asn Val Ala Met
                 425                 430                 435

 Val Met Ala Pro Asn Leu Phe Met Cys His Ala Leu Gly Leu Lys
                 440                 445                 450

 Ser Ser Glu Gln Arg Glu Phe Val Met Ala Ala Gly Thr Ala Asn
                 455                 460                 465

 Thr Met His Leu Leu Ile Lys Tyr Gln Lys Leu Leu Trp Thr Ile
                 470                 475                 480

 Pro Lys Phe Ile Val Asn Gln Val Arg Lys Gln Asn Thr Glu Asn
                 485                 490                 495

 His Lys Lys Asp Lys Arg Ala Met Lys Lys Leu Leu Lys Lys Met
                 500                 505                 510

 Ala Tyr Asp Arg Glu Lys Tyr Glu Lys Gln Asp Lys Ser Thr Asn
                 515                 520                 525

 Asp Ala Asp Val Pro Gln Gly Val Ile Arg Val Gln Ala Pro His
                 530                 535                 540

 Leu Ser Lys Val Ser Met Ala Ile Gln Leu Thr Glu Glu Leu Lys
                 545                 550                 555

 Ala Ser Asp Val Leu Ala Arg Phe Leu Ser Gln Glu Ser Gly Val
                 560                 565                 570

 Ala Gln Thr Leu Lys Lys Gly Glu Val Phe Leu Tyr Glu Ile Gly
                 575                 580                 585

 Gly Asn Ile Gly Glu Arg Cys Leu Asp Asp Asp Thr Tyr Met Lys
                 590                 595                 600

 Asp Leu Tyr Gln Leu Asn Pro Asn Ala Glu Trp Val Ile Lys Ser
                 605                 610                 615

 Lys Pro Leu


<210> 4142
<211> 3305
<212> DNA
<213> Homo sapien

<400> 4142
 tcgcagatat ggccagtaca ctatgaacca ggaaagcacc accatcaaag 50

 ttatggagaa gcctccattt gatcgatcaa tttcccagga ttctttggat 100

 gaactatcta tggaagacta ttggatagaa ctagaaaaca tcaagaaatc 150

 tagtgaaaac agccaagaag atcaagaggt ggttgttgtc aaagagcctg 200

 atgagggaga attggaagaa gagtggctta aagaggccgg tttatccaat 250

 ctcttcggag agtctgctgg agatccacag gaaagcattg tgtttttatc 300

 aacattgacg cggacccagg cagcagcagt tcagaagcga gtagagacgg 350

 tctcccagac cttgaggaaa aaaaacaaac agtaccagat tcctgacgtc 400

 agagacatat ttgctcaaca gagagaatca aaagaaacag ctccaggtgg 450

 cactgaatcg cagtcactta gaacaaatga aaacaaatac caaggaagag 500

 atgacgaggc atctaacctt gttggtgaag agaagctgat cccacctgag 550

 gagacgcctg cccctgaaac agacatcaac ctggaggtat catttgccga 600

 gcaagcactc aatcagaaag agagctccaa ggagaaaatc cagaagagca 650

 aaggcgatga tgccacatta cctagtttca gattgccaaa agacaaaacg 700

 ggtaccacaa ggattggtga cctcgcaccc caggacatga agaaagtttg 750

 ccatttagcc ctaattgagc tgactgccct ctatgatgta ttgggtattg 800

 agctgaaaca acaaaaagct gtgaaaatca aaacaaaaga ttctggtctt 850

 ttttgcgttc cattgacagc gctattagaa caagatcaga ggaaagtacc 900

 aggaatgcga atacccttga tctttcaaaa actgatttct cgaattgaag 950

 agagaggttt ggaaacagaa ggcctcttac ggatccctgg agctgccatt 1000

 agaatcaaga atctttgcca agaactagaa gcaaagtttt atgaagggac 1050

 ttttaattgg gaaagtgtca aacagcatga tgccgccagc ctgctgaagc 1100

 tcttcattcg ggagttgccc cagccactgc tcagtgtgga gtatctcaaa 1150

 gcctttcagg ctgtccagaa tcttccaacc aagaagcagc aactacaggc 1200

 tttgaacctt cttgtcatcc tcctacctga tgcaaacagg gacacactga 1250

 aggcccttct tgaatttctc caaagagtaa tagataataa agaaaaaaat 1300

 aaaatgacag tcatgaatgt agcaatggtc atggccccga atctctttat 1350

 gtgtcatgca ttgggattga agtccagtga acagcgagaa tttgtaatgg 1400

 cagctgggac agcaaatacc atgcacttat tgattaagta ccaaaaactt 1450

 ctgtggacaa ttcccaagtt tattgtaaac caagtgagga agcaaaacac 1500

 ggaaaatcat aaaaaggata aaagagccat gaagaaattg ctgaagaaaa 1550

 tggcttatga ccgagaaaaa tatgaaaagc aagataagag tacaaatgat 1600

 gctgacgttc ctcagggagt gattcgagtg caagctcccc atctttcgaa 1650

 agtttccatg gcaatacagc taactgaaga actaaaagcc agtgatgtac 1700

 ttgccaggtt tctcagccaa gaaagtgggg ttgcccagac tctcaagaaa 1750

 ggagaagttt ttttgtatga aattggagga aatattgggg aacgctgcct 1800

 tgatgatgac acttacatga aggatttata tcagcttaac ccaaatgctg 1850

 agtgggttat aaagtcaaag ccattgtaga agacttaaca agctgcagat 1900

 aaccatgtgg acttctgtca taattcttgc tgagtcaaga gtgtaaataa 1950

 aagaaatggc aggactcata ttattcagtt gtacccaagt atttaaaaat 2000

 gactctctta agccttaaaa agtcatagat ttgtgctgct gccagaatta 2050

 tattaattat tattaatgtt attattagaa aaaaaatttc tggagtgaga 2100

 gtaaagaggc ttaattagtt tgtgggcagt tttcatatgc tctgtgaaat 2150

 gtgtccagat gtgacatagt tttttttttt aatatgtgga aatgtcttct 2200

 cttcccattc ttttctccta aaatcatata tactgtaata tatgctctct 2250

 cacctctatt acctcctcac atctaccctt tcccagttag gtttgctttt 2300

 tgaccaaaaa gataacaaat accaggtatg gcaagttgtg aagacagcac 2350

 attaaaacat acctaatttc acagtattcc tgtcacgaca gaatgttagt 2400

 attcatctct ttgaatcatt tgctcaaata ataacattcc accttttcct 2450

 gctgtatcac aggaagtgat ttgcattttt tttcagttca tctgacttat 2500

 gttcacagaa ccgtatcagc gaccaagaaa ataggactgt cagaagctgc 2550

 cagttattac tgaaccatta aatacttata tactaagaat aaataaaata 2600

 tacccatgtg aaataataat tggattatgg ataacaagag agtgaaagcc 2650

 aaagcacttt ctgtctactg tactcttcta aatggaattt taaaagtcat 2700

 agctggcttt acgtgttgtc attattagca ttataaatat gcatgatagt 2750

 ataatccagt aatggttgaa gaatgtattt tacttaaaga gggatttttt 2800

 tttttaagtc ctgaataagt ctactggaag aattattctt ctgggtgaaa 2850

 aagcttttgt ttgtgttctt attttaaata atcggagtca atttattaaa 2900

 atgttcttga aagtactatt cccagggatt ttaatgcaca aaccatattg 2950

 tgacaagaga tgagcctctg tactgtaaat aagaaatgaa gtagagaaat 3000

 gttaaatatt ttatgagttt agaatatagt aaataaaagg tgatgtaaat 3050

 gaatgctgca caaacggtgt tcatgatact tttagtagta ctttaggaaa 3100

 aactacacat tctcagaagc tcttgatgtc tctaatgaag ggggggaatg 3150

 ctgttaatga gaacagtcat aaatttttag catataatta caagaacagc 3200

 ctgtggatat gatcacttaa atgattttgt ggtgattcgt gccattgctt 3250

 ttttatttaa aagaaaattt tgtaattaaa tgcctttttc taaattaaaa 3300

 aaaaa 3305

<210> 4143
<211> 618
<212> PRT
<213> Homo sapien

<400> 4143
 Met Asn Gln Glu Ser Thr Thr Ile Lys Val Met Glu Lys Pro Pro
   1               5                  10                  15

 Phe Asp Arg Ser Ile Ser Gln Asp Ser Leu Asp Glu Leu Ser Met
                  20                  25                  30

 Glu Asp Tyr Trp Ile Glu Leu Glu Asn Ile Lys Lys Ser Ser Glu
                  35                  40                  45

 Asn Ser Gln Glu Asp Gln Glu Val Val Val Val Lys Glu Pro Asp
                  50                  55                  60

 Glu Gly Glu Leu Glu Glu Glu Trp Leu Lys Glu Ala Gly Leu Ser
                  65                  70                  75

 Asn Leu Phe Gly Glu Ser Ala Gly Asp Pro Gln Glu Ser Ile Val
                  80                  85                  90

 Phe Leu Ser Thr Leu Thr Arg Thr Gln Ala Ala Ala Val Gln Lys
                  95                 100                 105

 Arg Val Glu Thr Val Ser Gln Thr Leu Arg Lys Lys Asn Lys Gln
                 110                 115                 120

 Tyr Gln Ile Pro Asp Val Arg Asp Ile Phe Ala Gln Gln Arg Glu
                 125                 130                 135

 Ser Lys Glu Thr Ala Pro Gly Gly Thr Glu Ser Gln Ser Leu Arg
                 140                 145                 150

 Thr Asn Glu Asn Lys Tyr Gln Gly Arg Asp Asp Glu Ala Ser Asn
                 155                 160                 165

 Leu Val Gly Glu Glu Lys Leu Ile Pro Pro Glu Glu Thr Pro Ala
                 170                 175                 180

 Pro Glu Thr Asp Ile Asn Leu Glu Val Ser Phe Ala Glu Gln Ala
                 185                 190                 195

 Leu Asn Gln Lys Glu Ser Ser Lys Glu Lys Ile Gln Lys Ser Lys
                 200                 205                 210

 Gly Asp Asp Ala Thr Leu Pro Ser Phe Arg Leu Pro Lys Asp Lys
                 215                 220                 225

 Thr Gly Thr Thr Arg Ile Gly Asp Leu Ala Pro Gln Asp Met Lys
                 230                 235                 240

 Lys Val Cys His Leu Ala Leu Ile Glu Leu Thr Ala Leu Tyr Asp
                 245                 250                 255

 Val Leu Gly Ile Glu Leu Lys Gln Gln Lys Ala Val Lys Ile Lys
                 260                 265                 270

 Thr Lys Asp Ser Gly Leu Phe Cys Val Pro Leu Thr Ala Leu Leu
                 275                 280                 285

 Glu Gln Asp Gln Arg Lys Val Pro Gly Met Arg Ile Pro Leu Ile
                 290                 295                 300

 Phe Gln Lys Leu Ile Ser Arg Ile Glu Glu Arg Gly Leu Glu Thr
                 305                 310                 315

 Glu Gly Leu Leu Arg Ile Pro Gly Ala Ala Ile Arg Ile Lys Asn
                 320                 325                 330

 Leu Cys Gln Glu Leu Glu Ala Lys Phe Tyr Glu Gly Thr Phe Asn
                 335                 340                 345

 Trp Glu Ser Val Lys Gln His Asp Ala Ala Ser Leu Leu Lys Leu
                 350                 355                 360

 Phe Ile Arg Glu Leu Pro Gln Pro Leu Leu Ser Val Glu Tyr Leu
                 365                 370                 375

 Lys Ala Phe Gln Ala Val Gln Asn Leu Pro Thr Lys Lys Gln Gln
                 380                 385                 390

 Leu Gln Ala Leu Asn Leu Leu Val Ile Leu Leu Pro Asp Ala Asn
                 395                 400                 405

 Arg Asp Thr Leu Lys Ala Leu Leu Glu Phe Leu Gln Arg Val Ile
                 410                 415                 420

 Asp Asn Lys Glu Lys Asn Lys Met Thr Val Met Asn Val Ala Met
                 425                 430                 435

 Val Met Ala Pro Asn Leu Phe Met Cys His Ala Leu Gly Leu Lys
                 440                 445                 450

 Ser Ser Glu Gln Arg Glu Phe Val Met Ala Ala Gly Thr Ala Asn
                 455                 460                 465

 Thr Met His Leu Leu Ile Lys Tyr Gln Lys Leu Leu Trp Thr Ile
                 470                 475                 480

 Pro Lys Phe Ile Val Asn Gln Val Arg Lys Gln Asn Thr Glu Asn
                 485                 490                 495

 His Lys Lys Asp Lys Arg Ala Met Lys Lys Leu Leu Lys Lys Met
                 500                 505                 510

 Ala Tyr Asp Arg Glu Lys Tyr Glu Lys Gln Asp Lys Ser Thr Asn
                 515                 520                 525

 Asp Ala Asp Val Pro Gln Gly Val Ile Arg Val Gln Ala Pro His
                 530                 535                 540

 Leu Ser Lys Val Ser Met Ala Ile Gln Leu Thr Glu Glu Leu Lys
                 545                 550                 555

 Ala Ser Asp Val Leu Ala Arg Phe Leu Ser Gln Glu Ser Gly Val
                 560                 565                 570

 Ala Gln Thr Leu Lys Lys Gly Glu Val Phe Leu Tyr Glu Ile Gly
                 575                 580                 585

 Gly Asn Ile Gly Glu Arg Cys Leu Asp Asp Asp Thr Tyr Met Lys
                 590                 595                 600

 Asp Leu Tyr Gln Leu Asn Pro Asn Ala Glu Trp Val Ile Lys Ser
                 605                 610                 615

 Lys Pro Leu


<210> 4144
<211> 3389
<212> DNA
<213> Homo sapien

<400> 4144
 agtgcctccc tccagactcg ggagggtcga gggggcgcgg gagagagcgc 50

 gggcggccgc cggggctggt cgcctgcagg gatgggggac gagcggcccc 100

 actactacgg gaaacacgga acgccacaga agtatgatcc cactttcaaa 150

 ggacccattt acaatagggg ctgcacggat atcatatgct gtgtgttcct 200

 gctcctggcc attgtgggct acgtggctgt aggcatcata gcctggactc 250

 atggagaccc tcgaaaggtg atctacccca ctgatagccg gggcgagttc 300

 tgcgggcaga agggcacaaa aaacgagaac aaaccctatc tgttttattt 350

 caacattgtg aaatgtgcca gccccctggt tctgctggaa ttccaatgtc 400

 ccactcccca gatctgcgtg gaaaaatgcc ccgaccgcta cctcacgtac 450

 ctgaatgctc gcagctcccg ggactttgag tactataagc agttctgtgt 500

 tcctggcttc aagaacaata aaggagtggc tgaggtgctt cgagatggtg 550

 actgccctgc tgtcctcatc cccagcaaac ccttggcccg gagatgcttc 600

 cccgctatcc acgcctacaa gggtgtcctg atggtgggca atgagacgac 650

 ctatgaggat gggcatggct cccggaaaaa catcacagac ctggtggagg 700

 gcgccaagaa agccaatgga gtcctagagg cgcggcaact cgccatgcgc 750

 atatttgaag attacaccgt ctcttggtac tggattatca taggcctggt 800

 cattgccatg gcgatgagcc tcctgttcat catcctgctt cgcttcctgg 850

 ctggtattat ggtctgggtg atgatcatca tggtgattct ggtgctgggc 900

 tacggaatat ttcactgcta catggagtac tcccgactgc gtggtgaggc 950

 cggctctgat gtctctttgg tggacctcgg ctttcagacg gatttccggg 1000

 tgtacctgca cttacggcag acctggttgg cctttatgat cattctgagt 1050

 atccttgaag tcattatcat cttgctgctc atctttctcc ggaagagaat 1100

 tctcatcgcg attgcactca tcaaagaagc cagcagggct gtgggatacg 1150

 tcatgtgctc cttgctctac ccactggtca ccttcttctt gctgtgcctc 1200

 tgcatcgcct actgggccag cactgctgtc ttcctgtcca cttccaacga 1250

 agcggtctat aagatctttg atgacagccc ctgcccattt actgcgaaaa 1300

 cctgcaaccc agagaccttc ccctcctcca atgagtcccg ccaatgcccc 1350

 aatgcccgtt gccagttcgc cttctacggt ggtgagtcgg gctaccaccg 1400

 ggccctgctg ggcctgcaga tcttcaatgc cttcatgttc ttctggttgg 1450

 ccaacttcgt gctggcgctg ggccaggtca cgctggccgg ggcctttgcc 1500

 tcctactact gggccctgcg caagccggac gacctgccgg ccttcccgct 1550

 cttctctgcc tttggccggg cgctcaggta ccacacaggc tccctggcct 1600

 ttggcgcgct catcctggcc attgtgcaga tcatccgtgt gatactcgag 1650

 tacctggatc agcggctgaa agctgcagag aacaagtttg ccaagtgcct 1700

 catgacctgt ctcaaatgct gcttctggtg cctggagaag ttcatcaaat 1750

 tccttaatag gaatgcctac atcatgattg ccatctacgg caccaatttc 1800

 tgcacctcgg ccaggaatgc cttcttcctg ctcatgagaa acatcatcag 1850

 agtggctgtc ctggataaag ttactgactt cctcttcctg ttgggcaaac 1900

 ttctgatcgt tggtagtgtg gggatcctgg ctttcttctt cttcacccac 1950

 cgtatcagga tcgtgcagga tacagcacca cccctcaatt attactgggt 2000

 tcctatactg acggtgatcg ttggctccta cttgattgca cacggtttct 2050

 tcagcgtcta tggcatgtgt gtggacacgc tgttcctctg cttcttggag 2100

 gacctggaga ggaatgacgg ctcggccgag aggccttact tcatgtcttc 2150

 caccctcaag aaacccttga acaagaccaa caagaaggca gcggagtcct 2200

 gaaggccccg tgctccccac ctctcaagga gtctcatgcc gcagggtgct 2250

 cagtagctgg gtctgttccc ccagcccctt gggctcacct gaagtcctat 2300

 cactgccgct ctgcccctcc ccatgagcca gatcccacca gtttctggac 2350

 gtggagagtc tggggcatct ccttcttatg ccaaggggcg cttggagttt 2400

 tcatggctgc ccctccagac tgcgagaaac aagtaaaaac ccattggggc 2450

 ctcttgatgt ctgggatggc acgtggcccg acctccacaa gctccctcat 2500

 gcttcctgtc ccccgcttac acgacaacgg gccagaccac gggaaggacg 2550

 gtgtttgtgt ctgagggagc tgctggccac agtgaacacc cacgtttatt 2600

 cctgcctgct ccggccagga ctgaacccct tctccacacc tgaacagttg 2650

 gctcaagggc caccagaagc atttctttat tattattatt ttttaacctg 2700

 gacatgcatt aaagggtcta ttagctttct ttccgtctgt ctcaacagct 2750

 gagatggggc cgccaaggag tgccttcctt ttgctccctc ctagctggga 2800

 gtgacgggtg ggagtgtgtg tgcccaggtg ggggtgtctc ctggctggga 2850

 aggagggaaa gggagggaga gttttgcggg ggttggcagt ggagagcagg 2900

 ctggagagga gatggctaat agctgtttaa tggaaacctg ctgggctgga 2950

 gggagttagg ctgaatttcc cgacttcctc tgccagttat tgacacagct 3000

 ctctttgtaa gagaggaaag aaactaaacc cacccaaggg atgatttcag 3050

 ggggagaggt ggagggcaga tgtcctgggc aaaccgggcc cctctgccca 3100

 cacacctcac ttgatccttt tgccaaactt gtcaaactca ggggaactgg 3150

 cttcccagtt gcccctttgc catattccaa gtccccctca gacttcatgt 3200

 ctctgctcat cagcactgtc ccaggatcct ggagagggag aacccctggc 3250

 cccaggggaa agaggggggg gtctcccgtt tcctgtgcct gcaccagccc 3300

 tgcccccatt gcgtctgcac acccctgcgt gtaactgcat tccaaccact 3350

 aataaagtgc ctattgtaca ggtaaaaaaa aaaaaaaaa 3389

<210> 4145
<211> 706
<212> PRT
<213> Homo sapien

<400> 4145
 Met Gly Asp Glu Arg Pro His Tyr Tyr Gly Lys His Gly Thr Pro
   1               5                  10                  15

 Gln Lys Tyr Asp Pro Thr Phe Lys Gly Pro Ile Tyr Asn Arg Gly
                  20                  25                  30

 Cys Thr Asp Ile Ile Cys Cys Val Phe Leu Leu Leu Ala Ile Val
                  35                  40                  45

 Gly Tyr Val Ala Val Gly Ile Ile Ala Trp Thr His Gly Asp Pro
                  50                  55                  60

 Arg Lys Val Ile Tyr Pro Thr Asp Ser Arg Gly Glu Phe Cys Gly
                  65                  70                  75

 Gln Lys Gly Thr Lys Asn Glu Asn Lys Pro Tyr Leu Phe Tyr Phe
                  80                  85                  90

 Asn Ile Val Lys Cys Ala Ser Pro Leu Val Leu Leu Glu Phe Gln
                  95                 100                 105

 Cys Pro Thr Pro Gln Ile Cys Val Glu Lys Cys Pro Asp Arg Tyr
                 110                 115                 120

 Leu Thr Tyr Leu Asn Ala Arg Ser Ser Arg Asp Phe Glu Tyr Tyr
                 125                 130                 135

 Lys Gln Phe Cys Val Pro Gly Phe Lys Asn Asn Lys Gly Val Ala
                 140                 145                 150

 Glu Val Leu Arg Asp Gly Asp Cys Pro Ala Val Leu Ile Pro Ser
                 155                 160                 165

 Lys Pro Leu Ala Arg Arg Cys Phe Pro Ala Ile His Ala Tyr Lys
                 170                 175                 180

 Gly Val Leu Met Val Gly Asn Glu Thr Thr Tyr Glu Asp Gly His
                 185                 190                 195

 Gly Ser Arg Lys Asn Ile Thr Asp Leu Val Glu Gly Ala Lys Lys
                 200                 205                 210

 Ala Asn Gly Val Leu Glu Ala Arg Gln Leu Ala Met Arg Ile Phe
                 215                 220                 225

 Glu Asp Tyr Thr Val Ser Trp Tyr Trp Ile Ile Ile Gly Leu Val
                 230                 235                 240

 Ile Ala Met Ala Met Ser Leu Leu Phe Ile Ile Leu Leu Arg Phe
                 245                 250                 255

 Leu Ala Gly Ile Met Val Trp Val Met Ile Ile Met Val Ile Leu
                 260                 265                 270

 Val Leu Gly Tyr Gly Ile Phe His Cys Tyr Met Glu Tyr Ser Arg
                 275                 280                 285

 Leu Arg Gly Glu Ala Gly Ser Asp Val Ser Leu Val Asp Leu Gly
                 290                 295                 300

 Phe Gln Thr Asp Phe Arg Val Tyr Leu His Leu Arg Gln Thr Trp
                 305                 310                 315

 Leu Ala Phe Met Ile Ile Leu Ser Ile Leu Glu Val Ile Ile Ile
                 320                 325                 330

 Leu Leu Leu Ile Phe Leu Arg Lys Arg Ile Leu Ile Ala Ile Ala
                 335                 340                 345

 Leu Ile Lys Glu Ala Ser Arg Ala Val Gly Tyr Val Met Cys Ser
                 350                 355                 360

 Leu Leu Tyr Pro Leu Val Thr Phe Phe Leu Leu Cys Leu Cys Ile
                 365                 370                 375

 Ala Tyr Trp Ala Ser Thr Ala Val Phe Leu Ser Thr Ser Asn Glu
                 380                 385                 390

 Ala Val Tyr Lys Ile Phe Asp Asp Ser Pro Cys Pro Phe Thr Ala
                 395                 400                 405

 Lys Thr Cys Asn Pro Glu Thr Phe Pro Ser Ser Asn Glu Ser Arg
                 410                 415                 420

 Gln Cys Pro Asn Ala Arg Cys Gln Phe Ala Phe Tyr Gly Gly Glu
                 425                 430                 435

 Ser Gly Tyr His Arg Ala Leu Leu Gly Leu Gln Ile Phe Asn Ala
                 440                 445                 450

 Phe Met Phe Phe Trp Leu Ala Asn Phe Val Leu Ala Leu Gly Gln
                 455                 460                 465

 Val Thr Leu Ala Gly Ala Phe Ala Ser Tyr Tyr Trp Ala Leu Arg
                 470                 475                 480

 Lys Pro Asp Asp Leu Pro Ala Phe Pro Leu Phe Ser Ala Phe Gly
                 485                 490                 495

 Arg Ala Leu Arg Tyr His Thr Gly Ser Leu Ala Phe Gly Ala Leu
                 500                 505                 510

 Ile Leu Ala Ile Val Gln Ile Ile Arg Val Ile Leu Glu Tyr Leu
                 515                 520                 525

 Asp Gln Arg Leu Lys Ala Ala Glu Asn Lys Phe Ala Lys Cys Leu
                 530                 535                 540

 Met Thr Cys Leu Lys Cys Cys Phe Trp Cys Leu Glu Lys Phe Ile
                 545                 550                 555

 Lys Phe Leu Asn Arg Asn Ala Tyr Ile Met Ile Ala Ile Tyr Gly
                 560                 565                 570

 Thr Asn Phe Cys Thr Ser Ala Arg Asn Ala Phe Phe Leu Leu Met
                 575                 580                 585

 Arg Asn Ile Ile Arg Val Ala Val Leu Asp Lys Val Thr Asp Phe
                 590                 595                 600

 Leu Phe Leu Leu Gly Lys Leu Leu Ile Val Gly Ser Val Gly Ile
                 605                 610                 615

 Leu Ala Phe Phe Phe Phe Thr His Arg Ile Arg Ile Val Gln Asp
                 620                 625                 630

 Thr Ala Pro Pro Leu Asn Tyr Tyr Trp Val Pro Ile Leu Thr Val
                 635                 640                 645

 Ile Val Gly Ser Tyr Leu Ile Ala His Gly Phe Phe Ser Val Tyr
                 650                 655                 660

 Gly Met Cys Val Asp Thr Leu Phe Leu Cys Phe Leu Glu Asp Leu
                 665                 670                 675

 Glu Arg Asn Asp Gly Ser Ala Glu Arg Pro Tyr Phe Met Ser Ser
                 680                 685                 690

 Thr Leu Lys Lys Pro Leu Asn Lys Thr Asn Lys Lys Ala Ala Glu
                 695                 700                 705

 Ser


<210> 4146
<211> 2829
<212> DNA
<213> Homo sapien

<400> 4146
 ccacgcgtcc gcacggaaca gggaactatc agcccgtcgg cctccgggcc 50

 ctgcattctc tagccatgga ccgggacctt ttgcggcagt cgctaaattg 100

 ccacgggtcg tctttgctct ctctacttcg gagcgaacag caggacaatc 150

 cacacttccg tagcctcctg gggtcggccg ccgagccagc ccggggcccg 200

 ccgccccagc acccgttgca gggcagaaaa gagaagagag ttgacaacat 250

 cgagatacag aaattcatct ccaaaaaagc ggatctgctt tttgcacttt 300

 cctggaaatc agatgcacct gcaacttctg aaattaatga agacagtgaa 350

 gatcattatg caatcatgcc acctttagag caattcatgg agatacctag 400

 tatggatcgg agagagctgt ttttccgaga tattgagcgt ggtgatatag 450

 tgattggaag aattagttct attcgggaat tcggtttttt catggtgttg 500

 atctgtttag gaagtggtat catgagagat atagcccact tagaaatcac 550

 agctctttgt cccttaagag atgtgccttc tcacagtaac catggggatc 600

 ctttatcata ttaccaaact ggtgacatca ttcgagctgg aatcaaggat 650

 attgacagat accatgaaaa gctagcagta tctctgtata gctcttctct 700

 tccaccacac ctatctggta ttaaattagg tgtaattagc tctgaagagc 750

 ttcctttata ctacaggaga agtgttgagc taaatagcaa ttctttggag 800

 tcctatgaaa atgtcatgca gagttccttg ggatttgtta atccaggagt 850

 agttgaattc cttctagaaa aactaggaat agatgaatct aatccaccat 900

 ctttaatgag aggcctacaa agcaaaaatt tctctgaaga tgattttgct 950

 tctgcattga gaaaaaaaca atccgcatct tgggctttaa aatgtgtgaa 1000

 gatcggagtt gactatttta aagttggacg ccatgtggat gctatgaatg 1050

 aatacaataa agctttggaa atagacaaac aaaacgtgga agctttggta 1100

 gctcgtggag cattatatgc gacaaaagga agtttgaaca aagcaataga 1150

 agattttgag cttgcattag aaaactgtcc aactcacaga aatgcaagaa 1200

 aatacctctg ccagacactt gtagagagag gaggacagtt agaagaagaa 1250

 gaaaagtttt taaatgctga aagttactat aagaaagctt tggctttgga 1300

 tgagactttt aaagatgcag aggatgcttt gcagaaactt cataaatata 1350

 tgcagaaatc tttggaatta agagaaaaac aagctgaaaa ggaagaaaag 1400

 cagaaaacaa agaaaataga aacaagtgca gaaaagttgc gtaagctctt 1450

 aaaagaagag aagaggctaa agaagaaaag aagaaaatca acttcttctt 1500

 caagtgtttc ttctgctgat gaatcagtgt cttcatcatc atcctcttcc 1550

 tcttctggtc acaaaaggca taagaaacat aagaggaacc gttcagagtc 1600

 ttctcgcagt tccagaaggc attcatctag ggcatcctca aatcagatag 1650

 atcagaatag gaaagatgag tgctacccag ttccagctaa tacttcagca 1700

 tcttttctta accataaaca agaagtggag aaactactgg ggaagcagga 1750

 taggttacag tatgaaaaga cacagataaa agagaaagat agatgccctc 1800

 tctcttcatc ttcacttgaa ataccggatg attttggagg taggtctgaa 1850

 gatccaagag atttttataa cagctataaa acccaagcag gtagtagcaa 1900

 aacagaaaag ccatataaat cagaaagaca tttttccagt agaagaaatt 1950

 cctcagattc cttctgtagg aattcagagg acaagattta tggttatagg 2000

 agatttgaaa aggatataga gggaagaaaa gagcactata gaaggtggga 2050

 accaggttct gtgaggcatt ctacctcacc agcaagctca gaatactctt 2100

 ggaagtcagt tgagaaatac aaaaaatacg ctcactctgg atcacgtgat 2150

 ttcagtagac atgagcaaag ataccgttta aatacaaatc aaggagaata 2200

 tgaaagagag gacaattatg gggaggatat caaaacagag gttccagaag 2250

 aagatgcact aagtagcaaa gaacactcag aaagcagtgt taagaaaaat 2300

 ttacctcaga atttactgaa tatatttaat cagatagctg aatttgaaaa 2350

 agaaaaagga aataagtcaa aaaattaata caccaaggat atcggcacca 2400

 ttacacaaaa tgccattaag tgaagttttt ggttgtatta gtcataacag 2450

 ttgagtgcag aaatctctgc ttctaaaatt atttgtagag attacaggaa 2500

 acaaatgctt ttaagtaagt ttttctcaaa ttttgtttca gttctaggtc 2550

 ccttgtcaca gcttggtttt tagacttttt atgtatatgt ttatgtacag 2600

 tatattactc ttgacagttt gaatttcttc acctaaagat aattctctga 2650

 aagtactgtt tcttcattct attgcggtat atgagaattc ctgggtgcat 2700

 cttattctgc tgtttgagag aaaaatttgt gcattgaaca cttggatcat 2750

 ttttataaaa attaatttca ttttcttttc tgttaaatta aaaatcgtca 2800

 gcttttgaaa gaaaaaaaaa aaaaaaaaa 2829

<210> 4147
<211> 770
<212> PRT
<213> Homo sapien

<400> 4147
 Met Asp Arg Asp Leu Leu Arg Gln Ser Leu Asn Cys His Gly Ser
   1               5                  10                  15

 Ser Leu Leu Ser Leu Leu Arg Ser Glu Gln Gln Asp Asn Pro His
                  20                  25                  30

 Phe Arg Ser Leu Leu Gly Ser Ala Ala Glu Pro Ala Arg Gly Pro
                  35                  40                  45

 Pro Pro Gln His Pro Leu Gln Gly Arg Lys Glu Lys Arg Val Asp
                  50                  55                  60

 Asn Ile Glu Ile Gln Lys Phe Ile Ser Lys Lys Ala Asp Leu Leu
                  65                  70                  75

 Phe Ala Leu Ser Trp Lys Ser Asp Ala Pro Ala Thr Ser Glu Ile
                  80                  85                  90

 Asn Glu Asp Ser Glu Asp His Tyr Ala Ile Met Pro Pro Leu Glu
                  95                 100                 105

 Gln Phe Met Glu Ile Pro Ser Met Asp Arg Arg Glu Leu Phe Phe
                 110                 115                 120

 Arg Asp Ile Glu Arg Gly Asp Ile Val Ile Gly Arg Ile Ser Ser
                 125                 130                 135

 Ile Arg Glu Phe Gly Phe Phe Met Val Leu Ile Cys Leu Gly Ser
                 140                 145                 150

 Gly Ile Met Arg Asp Ile Ala His Leu Glu Ile Thr Ala Leu Cys
                 155                 160                 165

 Pro Leu Arg Asp Val Pro Ser His Ser Asn His Gly Asp Pro Leu
                 170                 175                 180

 Ser Tyr Tyr Gln Thr Gly Asp Ile Ile Arg Ala Gly Ile Lys Asp
                 185                 190                 195

 Ile Asp Arg Tyr His Glu Lys Leu Ala Val Ser Leu Tyr Ser Ser
                 200                 205                 210

 Ser Leu Pro Pro His Leu Ser Gly Ile Lys Leu Gly Val Ile Ser
                 215                 220                 225

 Ser Glu Glu Leu Pro Leu Tyr Tyr Arg Arg Ser Val Glu Leu Asn
                 230                 235                 240

 Ser Asn Ser Leu Glu Ser Tyr Glu Asn Val Met Gln Ser Ser Leu
                 245                 250                 255

 Gly Phe Val Asn Pro Gly Val Val Glu Phe Leu Leu Glu Lys Leu
                 260                 265                 270

 Gly Ile Asp Glu Ser Asn Pro Pro Ser Leu Met Arg Gly Leu Gln
                 275                 280                 285

 Ser Lys Asn Phe Ser Glu Asp Asp Phe Ala Ser Ala Leu Arg Lys
                 290                 295                 300

 Lys Gln Ser Ala Ser Trp Ala Leu Lys Cys Val Lys Ile Gly Val
                 305                 310                 315

 Asp Tyr Phe Lys Val Gly Arg His Val Asp Ala Met Asn Glu Tyr
                 320                 325                 330

 Asn Lys Ala Leu Glu Ile Asp Lys Gln Asn Val Glu Ala Leu Val
                 335                 340                 345

 Ala Arg Gly Ala Leu Tyr Ala Thr Lys Gly Ser Leu Asn Lys Ala
                 350                 355                 360

 Ile Glu Asp Phe Glu Leu Ala Leu Glu Asn Cys Pro Thr His Arg
                 365                 370                 375

 Asn Ala Arg Lys Tyr Leu Cys Gln Thr Leu Val Glu Arg Gly Gly
                 380                 385                 390

 Gln Leu Glu Glu Glu Glu Lys Phe Leu Asn Ala Glu Ser Tyr Tyr
                 395                 400                 405

 Lys Lys Ala Leu Ala Leu Asp Glu Thr Phe Lys Asp Ala Glu Asp
                 410                 415                 420

 Ala Leu Gln Lys Leu His Lys Tyr Met Gln Lys Ser Leu Glu Leu
                 425                 430                 435

 Arg Glu Lys Gln Ala Glu Lys Glu Glu Lys Gln Lys Thr Lys Lys
                 440                 445                 450

 Ile Glu Thr Ser Ala Glu Lys Leu Arg Lys Leu Leu Lys Glu Glu
                 455                 460                 465

 Lys Arg Leu Lys Lys Lys Arg Arg Lys Ser Thr Ser Ser Ser Ser
                 470                 475                 480

 Val Ser Ser Ala Asp Glu Ser Val Ser Ser Ser Ser Ser Ser Ser
                 485                 490                 495

 Ser Ser Gly His Lys Arg His Lys Lys His Lys Arg Asn Arg Ser
                 500                 505                 510

 Glu Ser Ser Arg Ser Ser Arg Arg His Ser Ser Arg Ala Ser Ser
                 515                 520                 525

 Asn Gln Ile Asp Gln Asn Arg Lys Asp Glu Cys Tyr Pro Val Pro
                 530                 535                 540

 Ala Asn Thr Ser Ala Ser Phe Leu Asn His Lys Gln Glu Val Glu
                 545                 550                 555

 Lys Leu Leu Gly Lys Gln Asp Arg Leu Gln Tyr Glu Lys Thr Gln
                 560                 565                 570

 Ile Lys Glu Lys Asp Arg Cys Pro Leu Ser Ser Ser Ser Leu Glu
                 575                 580                 585

 Ile Pro Asp Asp Phe Gly Gly Arg Ser Glu Asp Pro Arg Asp Phe
                 590                 595                 600

 Tyr Asn Ser Tyr Lys Thr Gln Ala Gly Ser Ser Lys Thr Glu Lys
                 605                 610                 615

 Pro Tyr Lys Ser Glu Arg His Phe Ser Ser Arg Arg Asn Ser Ser
                 620                 625                 630

 Asp Ser Phe Cys Arg Asn Ser Glu Asp Lys Ile Tyr Gly Tyr Arg
                 635                 640                 645

 Arg Phe Glu Lys Asp Ile Glu Gly Arg Lys Glu His Tyr Arg Arg
                 650                 655                 660

 Trp Glu Pro Gly Ser Val Arg His Ser Thr Ser Pro Ala Ser Ser
                 665                 670                 675

 Glu Tyr Ser Trp Lys Ser Val Glu Lys Tyr Lys Lys Tyr Ala His
                 680                 685                 690

 Ser Gly Ser Arg Asp Phe Ser Arg His Glu Gln Arg Tyr Arg Leu
                 695                 700                 705

 Asn Thr Asn Gln Gly Glu Tyr Glu Arg Glu Asp Asn Tyr Gly Glu
                 710                 715                 720

 Asp Ile Lys Thr Glu Val Pro Glu Glu Asp Ala Leu Ser Ser Lys
                 725                 730                 735

 Glu His Ser Glu Ser Ser Val Lys Lys Asn Leu Pro Gln Asn Leu
                 740                 745                 750

 Leu Asn Ile Phe Asn Gln Ile Ala Glu Phe Glu Lys Glu Lys Gly
                 755                 760                 765

 Asn Lys Ser Lys Asn
                 770

<210> 4148
<211> 4018
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2276-2477
<223> Unknown base

<400> 4148
 aaccgcgcca tcgtgttggt acccgggaat tcggccatta tggccggggg 50

 aggccggttc cggcgaagtt aaaccctcgg agctggcctc ggactgctgg 100

 ggcgttaccc cttcggccac ccccgctgac catggcagtg tttcatgacg 150

 aggtggaaat cgaggacttc caatatgacg aggactcgga gacgtatttc 200

 tatccctgcc catgtggaga taacttctcc atcaccaagg atcagtttgt 250

 gtgtggagaa acagtcccag ccccttcagc caacaaagaa ttagttaaat 300

 gctgaagaag ccttcaggaa tccaaatcct gaacatttgg aatgagccca 350

 gatagaaata tcgaatgcaa agctactggc ttcacagaga caaccattta 400

 tgatttgctg ttctgtaaga gtgtggattc tttctatcaa ctgctgatat 450

 catcttcagg aagcaagtcc ataacatgac atatctggat tttgtgctta 500

 gaaccttaaa ttggaagcat tcttaattat gcatctaaat ttaaaagaag 550

 ataatttcaa aacagtgctt tctttccctt ggtttcatca ttttcatatc 600

 ttaaaccaaa ttacttcggt atctgacaac agcatcatct acctcagtca 650

 ttaggatttc ttaataaaaa agagattgta tttttgactt ggttattaag 700

 attattaaaa ttagcccttc ctttgaaata tgacatcagc tttgctgttc 750

 taaatttaaa attagttgct tcatcagtac cacacttcca gtttctatac 800

 caagccagtc tcctcagttt tcccattaga atggacatgt tctgttcagc 850

 gtgtcatttc tgtaatgctt catgcagaga gtttggtcat agtattaaag 900

 agaaaataca gtgaggtcac aatgtctcca gagctaaaag ttagtgaaca 950

 agaaagaaag tccaaaatga agtgatgaaa gaatgaggac ttttcttata 1000

 ttctgcatat ttcttggaag tcaggacaag atgaaaagaa aaacatccaa 1050

 aagaagtgaa attggtgaca gaatgagagg agcaaagcat accagtgtag 1100

 taagtggaat gtttgaatga ctttgccagg tcagagcaag taatatttct 1150

 gtatctgagt ttttgtttgt gttttgataa ggctaatgaa attgcattcc 1200

 aggtaggggt taacgtcaaa tttccatggc tggtagctgt gcttttggca 1250

 tatcacagtg ttgtgtcact actacaaggt aaagcatcta cagcggagaa 1300

 tgagcttgaa aatgagagac ctattgtgaa taaatatgcc catgagagca 1350

 tatttaataa gcctctataa catgcagcca aaccagacat tcactcctgc 1400

 agagaaatgt tgccctggag aaaaagagat atataaagat aggctatcac 1450

 ccttcttttg ctgcagtact aagcatagca agaaattaga atcatttaca 1500

 ttggaaattt gaaaattccc tttatataca caactttact gtgtataaat 1550

 aaaaaatatt tattaatgca gtgatgtccg tcaggttgtt ttaggaatgg 1600

 cttctgcaat tagaaaaata gcttgctaga atgtaaatgt tctgttactg 1650

 gtaaatgtac tgcacacatt cattggacgt taaaacaagt gagtagcctt 1700

 ttttacctgc cagcagcatg gctgtgtgca gccactaggc tgagacaata 1750

 aattaccaaa aattataatg taccgagctg aaaatgctca gtacattatg 1800

 tggcatattc tggatgtgat gagaaatctc attgccattt gggacactga 1850

 catcccagaa gtaatccaca actgctttgc aaaagcaaag tgactgctca 1900

 gatgaacaga gcagagtact cactcactat ggtggcatca gctgcaaagc 1950

 aaaatgaact gtcccatgat catgttgatg gttttctaga tactgccaac 2000

 atgttagctc tttctgatgc tgatgagttt caaacacgaa cagacaccct 2050

 tgatgtgggt ttgctaagaa catagaagaa caggaagaaa agttgccagg 2100

 ttcacacatc ccaggaaaaa agaagcataa aaagcattag cagtcagtga 2150

 ctgatgataa tgctgcaata atgggaatgg ttttgtttct aaaccaaatt 2200

 atttctaaat caaatcattt attgctttgt ttctaaagca gttgagtcac 2250

 taagtttgtg aactgtagga gaacannnnn nnnnnnnnnn nnnnnnnnnn 2300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnagc aaaattgctt tgggccccag 2500

 gagtttgagg ctgtgggtga gctgtgatca cacccacttg cgttcccagc 2550

 ctgtgtgaca tgggcaagac ctcatgccta aaaaataaag agaaagcaga 2600

 gtaaaactgg actctgagat atgactaaag ttctgtgtga tacgtgtgcc 2650

 ttatttagct caagacattc ctggagcacc tataaaaact gacttgtaat 2700

 ccaggctatg tctcttttta gcttcgtaat ctttggcaag gccattggat 2750

 tcttcagctg tacaattagg agactcgatc aggtgattgc ctttctcagc 2800

 tgtcagttct ctaatttcag gcttggtagc ttgtaggaac tgaaattgca 2850

 attaaaacct ttataaactc aaactaaatc atgaattaca gaaaaagtcc 2900

 attcttccaa aacttgatgt taccacactt acaagtttaa aatatgaagt 2950

 cgactgttta aaggattctg catatattct agtgtgcaca ttcagaaaca 3000

 tttttcttgg aaaaagtacc caacattttt tataactgca catattaatt 3050

 tattgccaga ataaattgca ttgcatgcta aataaagtca gataattcaa 3100

 atccatttgc ttttatgtag tttttcttct aaatgtcaac attttgaatt 3150

 aaaatgttta tgattttata tgaggtagaa atcttaactg ctttggggta 3200

 ttgttaatag actttttgtt atggacagta gtttttaaat aaggaaattg 3250

 ccaatttcta cagtttgggc tctggatttc tattgtttgg gaaaaaaata 3300

 actgagtcaa gtggtagtaa gacaaagttg acattcttag atgagtaact 3350

 cagtttatta caaggaaaga aaactgattg tttaaggctg atgatcaatt 3400

 cttggagtgg tttcagagcc cagctctggt cagaagacaa tttgaatctt 3450

 agttcctcca ctgtgatctc cgagaagtta cttaataatt atattctggt 3500

 ttgtgaaatc tggatcatag tacctctttg acagggttgc tgtgtgaacc 3550

 cattcattct gcaattagaa aaatagctgt catgtgctat gcactaggca 3600

 aagaagtacc tgtcacatgc taggcactag gggaagaaga ttcggtttct 3650

 acatttggaa acttagtgga actagaagag acagaagcaa gattacagat 3700

 gagttagagc ccccaaggaa acaaaccagg tgatgtggga gagagtaact 3750

 gggtcaggtg actttttaag ggagtctgag ctctggcact ttttctaaga 3800

 cctgaaggat gagaaggaaa cagccttgtg aaaatgatta aatgagctag 3850

 tatctataaa acatgacagc taatgcctgt catgtgcaaa aaatggttaa 3900

 ctattctaac tccgaaagga attaaacatt gttttgcgct ttctcctagt 3950

 ccatgttctg ctgctgtaac aatacctgag actggataat ttatcaagaa 4000

 taaaggttaa tttggctc 4018

<210> 4149
<211> 100
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2276-2477
<223> Unknown amino acid

<400> 4149
 Pro Arg His Arg Val Gly Thr Arg Glu Phe Gly His Tyr Gly Arg
   1               5                  10                  15

 Gly Arg Pro Val Pro Ala Lys Leu Asn Pro Arg Ser Trp Pro Arg
                  20                  25                  30

 Thr Ala Gly Ala Leu Pro Leu Arg Pro Pro Pro Leu Thr Met Ala
                  35                  40                  45

 Val Phe His Asp Glu Val Glu Ile Glu Asp Phe Gln Tyr Asp Glu
                  50                  55                  60

 Asp Ser Glu Thr Tyr Phe Tyr Pro Cys Pro Cys Gly Asp Asn Phe
                  65                  70                  75

 Ser Ile Thr Lys Asp Gln Phe Val Cys Gly Glu Thr Val Pro Ala
                  80                  85                  90

 Pro Ser Ala Asn Lys Glu Leu Val Lys Cys
                  95                 100

<210> 4150
<211> 1038
<212> DNA
<213> Homo sapien

<400> 4150
 ggcacgaggc tcggccatgc tacgcgcgct gagccgcctg ggcgcgggga 50

 ccccgtgcag gccccgggcc cctctggtgc tgccagcgcg cggccgcaag 100

 acccgccacg acccgctggc caaatccaag atcgagcgag tgaacatgcc 150

 gcccgcggtg gaccctgcgg agttcttcgt gctgatggag cgttaccagc 200

 actaccgcca gaccgtgcgc gccctcagga tggagttcgt gtccgaggtg 250

 cagaggaagg tgcacgaggc ccgagccggg gttctggcgg agcgcaaggc 300

 cctgaaggac gccgccgagc accgcgagct gatggcctgg aaccaggcgg 350

 agaaccggcg gctgcacgag ctgcggatag cgaggctgcg gcaggaggag 400

 cgggagcagg agcagcggca ggcgttggag caggcccgca aggccgaaga 450

 ggtgcaggcc tgggcgcagc gcaaggagcg ggaagtgctg cagctgcagg 500

 aagaggtgaa aaacttcatc acccgagaga acctggaggc acgggtggaa 550

 gcagcattgg actcccggaa gaactacaac tgggccatca ccagagaggg 600

 gctggtggtc aggccacaac gcagggactc ctaggggccc agtaaggaca 650

 gtgcccgcca gggaccatgt atgtatcatg gcggaagagt tggccctgac 700

 ctggaataaa gcagttggtg ttgcttatga ggaaggttca gccttatcca 750

 gcacagcctt cacgttttgc cctctgctgt caccacttgg tcagaaactt 800

 ccaaacgcag tgccctgttc tgccggtgtg tacagcctca gcgcaccagg 850

 agaccctaga gtggtttcca tctcacagag aatcagacag ggccacagcc 900

 ccctcaggca gccaggtcat ctgagtatca ttaagagtag tgatgggaag 950

 attacagtct gagggccaaa cgtgcctgct tcctgttttt gtaaataaag 1000

 ttttgttgga acacaaaaaa aaaaaaaaaa aaaaaaaa 1038

<210> 4151
<211> 205
<212> PRT
<213> Homo sapien

<400> 4151
 Met Leu Arg Ala Leu Ser Arg Leu Gly Ala Gly Thr Pro Cys Arg
   1               5                  10                  15

 Pro Arg Ala Pro Leu Val Leu Pro Ala Arg Gly Arg Lys Thr Arg
                  20                  25                  30

 His Asp Pro Leu Ala Lys Ser Lys Ile Glu Arg Val Asn Met Pro
                  35                  40                  45

 Pro Ala Val Asp Pro Ala Glu Phe Phe Val Leu Met Glu Arg Tyr
                  50                  55                  60

 Gln His Tyr Arg Gln Thr Val Arg Ala Leu Arg Met Glu Phe Val
                  65                  70                  75

 Ser Glu Val Gln Arg Lys Val His Glu Ala Arg Ala Gly Val Leu
                  80                  85                  90

 Ala Glu Arg Lys Ala Leu Lys Asp Ala Ala Glu His Arg Glu Leu
                  95                 100                 105

 Met Ala Trp Asn Gln Ala Glu Asn Arg Arg Leu His Glu Leu Arg
                 110                 115                 120

 Ile Ala Arg Leu Arg Gln Glu Glu Arg Glu Gln Glu Gln Arg Gln
                 125                 130                 135

 Ala Leu Glu Gln Ala Arg Lys Ala Glu Glu Val Gln Ala Trp Ala
                 140                 145                 150

 Gln Arg Lys Glu Arg Glu Val Leu Gln Leu Gln Glu Glu Val Lys
                 155                 160                 165

 Asn Phe Ile Thr Arg Glu Asn Leu Glu Ala Arg Val Glu Ala Ala
                 170                 175                 180

 Leu Asp Ser Arg Lys Asn Tyr Asn Trp Ala Ile Thr Arg Glu Gly
                 185                 190                 195

 Leu Val Val Arg Pro Gln Arg Arg Asp Ser
                 200                 205

<210> 4152
<211> 706
<212> DNA
<213> Homo sapien

<400> 4152
 ataggctccg cccctcgcgg cgcttccccc ggaatagcgt catcagttct 50

 ataagagagc gtgtgccgaa ggcctcggcc tttcacattc gggaagcgtc 100

 gggattaggt gaaagtacgt agttgtcttt cgtaagttaa aatgataatt 150

 gggccgaaac ttactgcctt acctaaaagg cagcgcagtc aggatattgg 200

 taggtcgggg gcggctttgg aaacccttaa gtttacaagc atgcgcggac 250

 ttgagtgctc attaggtcgc cgggcgtcca cgtgcagccc tggaccctga 300

 accccggcgt gcgtgggccg tgggccctcg gggaaaggtt ccgtgcactc 350

 ggggactccg gtgaagcctg ttcagccgtc tgtgtcatgt ggccatcttg 400

 agtctactct gtcgctcttg tgccctagca ccccgagaac cgtcagtttg 450

 agccagatgg aagctgagct gaacacatta cgatggatga tggaaacata 500

 agactatcaa gaaatccaag tggtaatggg cgaagtttat tcagcatccg 550

 gcaatggact tatcgtagtt ggggaaacgg gtgttccgaa taatatcctg 600

 gaagttatca ggacacctat tttaaatata ggcctgaatt ttgtaaagta 650

 atatttaagg tggtccgtga taattaaata aaatgcttaa ttcatgtggc 700

 taaaac 706

<210> 4153
<211> 52
<212> PRT
<213> Homo sapien

<400> 4153
 Met Ile Ile Gly Pro Lys Leu Thr Ala Leu Pro Lys Arg Gln Arg
   1               5                  10                  15

 Ser Gln Asp Ile Gly Arg Ser Gly Ala Ala Leu Glu Thr Leu Lys
                  20                  25                  30

 Phe Thr Ser Met Arg Gly Leu Glu Cys Ser Leu Gly Arg Arg Ala
                  35                  40                  45

 Ser Thr Cys Ser Pro Gly Pro
                  50

<210> 4154
<211> 2580
<212> DNA
<213> Homo sapien

<400> 4154
 ggtatggccc ggccggagtt aaggccgggg ggaggcggcg agtcccgcgg 50

 cggcggcgac gatggggctg cgtgcaggag gaacgctggg cagggccggc 100

 gcgggtcggg gggcgcccga ggggcccggg ccgagcggcg gcgcgcaggg 150

 cggcagcatc cactcgggcc gcatcgccgc ggtgcacaac gtgccgctga 200

 gcgtgctcat ccggccgctg ccgtccgtgt tggaccccgc caaggtgcag 250

 agcctcgtgg acacgatccg ggaggaccca gacagcgtgc cccccatcga 300

 tgtcctctgg atcaaagggg cccagggagg tgactacttc tactcctttg 350

 ggggctgcca ccgctacgcg gcctaccagc aactgcagcg agagaccatc 400

 cccgccaagc ttgtccagtc cactctctca gacctaaggg tgtacctggg 450

 agcatccaca ccagacttgc agtagcagcc tccttggcac ctgctgccac 500

 cttcaagagc ccagaagaca cacctggcct ccagcaggct gggccatgca 550

 gaagggatag caggggtgca ttctctttgc acctggcgag agggtctgac 600

 tctgggcacc cctctcacca gctacaaggc cttggactca ctgtacagtg 650

 tgggagcccc agttcccacc tctgtgacaa taggatcatg gccttaccct 700

 tgaagcatta ccgagaagga gaacagagat gggcttgaag agccacgtgc 750

 tgccggctcc aaattcccaa ggacaaggat ccctctgcat ttttgtctat 800

 gtaacctctt atatggacta cattcagctg caaggaaagg aaaaccttga 850

 ttgcagtggt ttaaacaaac agaagattgt ttttccacat agcatggatt 900

 ctggagatgg gtggctaatg gtattggttc aacaactcca cgaaggtagg 950

 ggtcacgtct tggatccttt tgccttaatc tcagtgctcg ttacttcatg 1000

 gtcccaagat ggctgctgta tccccaagaa tcatgtctgc gttcaaggaa 1050

 ggaggggtgg aggaagagga agggccaaac tagctggacc cgtcaccttc 1100

 tatcagaaag taaaacctcg tcagaagtct gtttcctgct ctctccctct 1150

 gcatatcttc acttagatgc ccttggcccg agccagctac cattgcacct 1200

 ctagctgcaa acaaagctaa gacagcaggg aacagaattg tcatggctga 1250

 atagaccaat cgtgttccat ctactgagac tggcacactg cctcctgcaa 1300

 taaaactggg atcccattac caagagagaa atgcagaatt gtgtaccagt 1350

 tagcttttgc tgtgtaacaa accatcccca aacttggcag ctagaaacaa 1400

 accctgtatt ttcccacaat cctatgggtt ggcaatttgg gctgggctca 1450

 acagggcagt tctgctgctc acacctggga tccctcatgg agctaaggtc 1500

 agctgttacc tcagctgggc ctggatggtc taggatagcc ttactcactt 1550

 gcctggcagg tgacaggctg ttggctggaa ttgcttggtt ctcctccatg 1600

 tggcctctcc agcaggctag ctcaggctta ttcacatgat ggcttcagga 1650

 ttccaaagag agtgagagta gaagctgaaa gacttcttga gttcttggcc 1700

 tggaactggg actaggacag tgtcacttct gctaagttct tttggtcaga 1750

 gcaaatcaca aggctttacc cagattcaag ggatgagaaa cagactacat 1800

 gtcttgatga ggggaaccac aaagagcttg tggccatttt tcacctatca 1850

 caaataattt tggatgggta tttatttgga taaaggtatt tccctcttcc 1900

 ccctttctct ctgtctcatg gggcctcact ctgccaagtt ggaaggcact 1950

 aagacattgt cctggccctc agggtctagg ggaagaggtg ttggggcagg 2000

 aagtgagtct ctccatgggc tggacccact gtagtaggag tgcctccttg 2050

 tctgcactgc tggtatgggg ttaggccagg taggacattc cagaggggct 2100

 tctgaaaacc aagagtccct ggggaaaggg aacagagtaa ggcaggcctt 2150

 gttctcactg ccctctaagg gaacttggtc actcggcact tttaagcctc 2200

 agtttctcca gttcaataat aaggacaaga gcttttccca tgcattctct 2250

 ttccccggga aagttgactg aggtgaccag taatagaatt gaaaagggag 2300

 agtgtcttca gtgcaatgtg gcatcctgga ttgggtcttg gaacaaaaac 2350

 aggacattag tgggaaaatt ggaaatctga aaaaagtctg aattttagtt 2400

 aatataccaa tttcagtctc ttggttttga cagatgtacc atggtgatgt 2450

 aagatgttga ccttggggta ggctgggtga agggtataca ggaactcttt 2500

 gtactatctc tgcaacttct ctgtaaatct agtatcattc caaaataaaa 2550

 gtttatttaa tttaaaaaaa aaaaaaaaaa 2580

<210> 4155
<211> 137
<212> PRT
<213> Homo sapien

<400> 4155
 Met Gly Leu Arg Ala Gly Gly Thr Leu Gly Arg Ala Gly Ala Gly
   1               5                  10                  15

 Arg Gly Ala Pro Glu Gly Pro Gly Pro Ser Gly Gly Ala Gln Gly
                  20                  25                  30

 Gly Ser Ile His Ser Gly Arg Ile Ala Ala Val His Asn Val Pro
                  35                  40                  45

 Leu Ser Val Leu Ile Arg Pro Leu Pro Ser Val Leu Asp Pro Ala
                  50                  55                  60

 Lys Val Gln Ser Leu Val Asp Thr Ile Arg Glu Asp Pro Asp Ser
                  65                  70                  75

 Val Pro Pro Ile Asp Val Leu Trp Ile Lys Gly Ala Gln Gly Gly
                  80                  85                  90

 Asp Tyr Phe Tyr Ser Phe Gly Gly Cys His Arg Tyr Ala Ala Tyr
                  95                 100                 105

 Gln Gln Leu Gln Arg Glu Thr Ile Pro Ala Lys Leu Val Gln Ser
                 110                 115                 120

 Thr Leu Ser Asp Leu Arg Val Tyr Leu Gly Ala Ser Thr Pro Asp
                 125                 130                 135

 Leu Gln


<210> 4156
<211> 5306
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2899-2999
<223> Unknown base

<400> 4156
 gttaaaaacc aaggacctga tatcttataa ttcagtttaa gcctaataca 50

 gttcatgtaa actccttttt tggcaattta acatatacat ggatcaagtt 100

 tagtaggttt agaggaaaat gaatgtcttg ttctgaaaaa atagcagtac 150

 cagctgagct ttggggaggt gacagattga gtcacttcac agcttaattc 200

 tgttatgaac tggtcccatg ggcatggatt gtcaattagg gagacttgaa 250

 tcttttagat attaaatcta caggcagaca acaaagaaca cattattctt 300

 ttgtaaaaat agaggaacct ggctgtctac tacagaacta gaggaaccta 350

 gcttagacag aagctcatcc cacttcagca cctacaacag atttgatacc 400

 tttgagcaag attggatact tttctcaaag taaatactgg gttggtaccc 450

 cagagttatg caccactgaa catggatttt aacttaaaat acttaagggc 500

 agatttttac tgttagtttt cttgactaac agagcaaccc agtgcagttc 550

 ctaaagactt ctgattttgt gtagcaccag ctcctgttgc attttctgaa 600

 tgaattagta ttaaaaatgg agccccaaga agctggttaa atttttagcc 650

 ttctgcattt aagctgtagc ccaggctgtg agctagtatc gcatcttatt 700

 cattatccaa catagaacca ggtttacaac aggcactcaa aatgtttgtg 750

 ggatgaatga atgagaaact gccaattctg gggatttctg tttcagaaga 800

 gttgatgcta agctgttctt tctaacaatg gttcccaggt tcagctgttt 850

 cagtccacac cttgttcaca gtaagatatt caattcaatt cagcaaacat 900

 ttgttgtgtg cttgctgctc tgtgcctgac cagaagaaat gaagccaaga 950

 tacaaataat agaaccctgt catgagcaca gaaagacctg gtgagtttct 1000

 attgattgtg gtaaaccagc ctgcatccag ttccaagtaa cagctgccca 1050

 cttagtgaat actctctcat gtttcaacac tcagttctag tgtagcctct 1100

 tctataaagc ctttcttttc cagatgcagc tcaaaaagct gtgtctgccc 1150

 tgaaggccag tggggttcaa gctcaaatgg caaagcaaca ggaacaagat 1200

 cctaccaacc tctacatttc taatttgcca ctctccatgg atgagcaaga 1250

 actagaaaat atgctcaaac catttggaca agttatttct acaaggatac 1300

 tacgtgattc cagtggtaca agtcgtggtg ttggctttgc taggatggaa 1350

 tcaacagaaa aatgtgaagc tgttattggt cattttaatg gaaaatttat 1400

 taagacacca ccaggagttt ctgcccccac agaaccttta ttgtgtaagt 1450

 ttgctgatgg aggacagaaa aagagacaga acccaaacaa atacatccct 1500

 aatggaagac catggcatag agaaggagag gtgagacttg ctggaatgac 1550

 acttacttac gacccaacta cagctgctat acagaacgga ttttatcctt 1600

 caccatacag tattgctaca aaccgaatga tcactcaaac ttctattaca 1650

 ccctatattg catctcctgt atctgcctac caggtgcaaa gtccttcgtg 1700

 gatgcaacct caaccatata ttctacagca ccctggtgcc gtgttaactc 1750

 cctcaatgga gcacaccatg tcactacagc ccgcatcaat gatcagccct 1800

 ctggcccagc agatgagtca tctgtcacta ggcagcaccg gaacatacat 1850

 gcctgcaacg tcagctatgc aaggagccta cttgccacag tatgcacata 1900

 tgcagacgac agcggttcct gttgaggagg caagtggtca acagcaggtg 1950

 gctgtcgaga cgtctaatga ccattctcca tatacctttc aacctaataa 2000

 gtaactgtga gatgtacaga aaggtgttct tacatgaaga agggtgtgaa 2050

 gctgttattg gtcattttaa tggaaaattt attaagacac caccaggagt 2100

 ttctgccccc acagaacctt tattgtgtaa gtttgctgat ggaggacaga 2150

 aaaagagaca gaacccaaac aaatacatcc ctaatggaag accatggcat 2200

 agagaaggag aggctggaat gacacttact tacgacccaa ctacagctgc 2250

 tatacagaac ggattttatc cttcaccata cagtattgct acaaaccgaa 2300

 tgatcactca aacttctatt acaccctata ttgcatctcc tgtatctgcc 2350

 taccaggtgc aaagtccttc gtggatgcaa cctcaaccat atattctaca 2400

 gcaccctggt gccgtgttaa ctccctcaat ggagcacacc atgtcactac 2450

 agcccgcatc aatgatcagc cctctggccc agcagatgag tcatctgtca 2500

 ctaggcagca ccggaacata catgcctgca acgtcagcta tgcaaggagc 2550

 ctacttgcca cagtatgcac atatgcagac gacagcggtt cctgttgagg 2600

 aggcaagtgg tcaacagcag gtggctgtcg agacgtctaa tgaccattct 2650

 ccatatacct ttcaacctaa taagtaactg tgagatgtac agaaaggtgt 2700

 tcttacatga agaagggtgt gaaggctgaa caatcatgga tttttctgat 2750

 caattgtgct ttaggaaatt attgacagtt ttgcacaggt tcttgaaaac 2800

 gttatttata atgaaatcaa ctaaaactat ttttgctata agttctataa 2850

 ggtgcataaa acccttaaat tcatctagta gctgttcccc cgaacaggnn 2900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc 3000

 ttcaattttc tgggtatgca caaagaccat gaagacttat ccaagtgcat 3050

 gaccggattt ttgtggtttt gttcattttg tgtttaattt gtgttttttt 3100

 ttttccagct gtatgaaatg ggctttctga agtttaaata gtccgacttc 3150

 acccatggtg ttctgtgctt gcagtgcgag tgttgctgta attcagtgtt 3200

 gccgtcagtg tctcttttct tagctttctg tctttctttc aacgtagtgt 3250

 gaagtgtctt atccttttct atgaattcca atttgcctta actcttttga 3300

 tgctgtagct gtttcagtaa aagttagttc aaactaatga tgtagaatgc 3350

 tttgaccaaa tgagctggtc tattatgcct tgtaaaacag cagcataggg 3400

 cttttaaaag gtagtcaata aaagttgctg aaattttggc ttttttaaat 3450

 atgtagtagg tgtttttaat gatttttcac ataatgtgta aggtagtgaa 3500

 atgcaagaag ggaaaaatgt tttgtgtgaa acacattttc tgactgggga 3550

 acttttatta gggtaaattg tttgtaaggc tgtacgccaa cagtttcctc 3600

 tgatagtttg actgatttag gatatctgct gtatgatgca atgtaaagtc 3650

 ttttttgcct tttttcagga aaaaaaaaaa agctaacttg atgtactaga 3700

 tttagtgtag gtagtgttgg ggttggggat gggggtgggg gaggggagtc 3750

 actgaatgtt ttgtccttcc tttatactaa tgatagtgct ttagaatgag 3800

 aattatgcct gaaatctggc aaaccgaaaa atgttgctat tgcaacaaag 3850

 tggcaaaagc taaaagtaag gatttatctt caaacataag ctgagataac 3900

 gaatagaagc aaaacgattg gctactagct ctctctctct ctctctatta 3950

 ggtaaatttg aaaaataaaa atgacttggc acttttaaag gtaacttcac 4000

 caaagaccga agagccagta accagtagct ccaacttgtc tcagcatcac 4050

 atcttctgtg ctctttattt ttgccggacc agtttgcggt taggagaatg 4100

 tgcctttttt gtacctttgc atttaggttt tataatttta attgatgtat 4150

 ggacacacac aaacaaaaaa gcatgaagga agatttggat ccaagcagtg 4200

 ccacacttta catcatcact acaagtgttc aagtgtaaag aaaaccaatt 4250

 ttgaaactat gaaattcctg attcataaat acacagttat ttctacttta 4300

 gtacatataa gataattcac tgttattaaa gctcttttat taaggcaatt 4350

 gcatatgttt taaaagcaat ggtaaattaa gttgtcttcc aaaactgtgt 4400

 acttgtctgg tcagctgtgt atgatcagtt atctacctca gagtctattt 4450

 tcttttgtgc tgggacaggt tgctggccct ccctgtttcc acagaccaaa 4500

 tcctcctagc tcaggagcta gggctaagca gttatttctt tcaagtattt 4550

 tttagttctt aaattttatg cttgtatttg atgatagatg tcagtgacat 4600

 ttcatagttt caaaagtcct tgctgctctg agaagtgtag attctagtga 4650

 aaattacata gtcataagag aaatgtgttt ttgtttttgt ttttgtttca 4700

 tttttttaaa gttgtggtat tattggttct atgctccctg gaatattact 4750

 gctttgtgaa agtccagact gaacgcagca ccctctgtgt acctagtaca 4800

 gttataaacc tgggtctctc actacttgat atttttgcat tagttaagac 4850

 agaaatttga tagctcggtt agaggggagg ggaaatctgc tgctagaaat 4900

 gtctgaacta agtgccatac tcgtctgggt aagatttggg aaacataacc 4950

 tctgtacata aaaaaaaaaa aatcagttaa acatcacata gtagacagcc 5000

 attaaattat aaaaaaatta atttatgaag aaagaccttt tgtacagatt 5050

 gaaaaaaaaa gattttcata gagatatcta tatgatcaag agagttaatt 5100

 ttttattttt gttttactag tgccacagac ttgccagtgg taacttattt 5150

 gtccggttca agataactct gtagttttct ttcctaggac ttgttgttaa 5200

 acgccaaaag acatttttga actgtacatt tgatcagatt gttagctttt 5250

 ctgttttatt tcttttgaga acctttgaat aaaaaacatc tgaaatttta 5300

 aaaaaa 5306

<210> 4157
<211> 499
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2899-2999
<223> Unknown amino acid

<400> 4157
 Met Ala Lys Gln Gln Glu Gln Asp Pro Thr Asn Leu Tyr Ile Ser
   1               5                  10                  15

 Asn Leu Pro Leu Ser Met Asp Glu Gln Glu Leu Glu Asn Met Leu
                  20                  25                  30

 Lys Pro Phe Gly Gln Val Ile Ser Thr Arg Ile Leu Arg Asp Ser
                  35                  40                  45

 Ser Gly Thr Ser Arg Gly Val Gly Phe Ala Arg Met Glu Ser Thr
                  50                  55                  60

 Glu Lys Cys Glu Ala Val Ile Gly His Phe Asn Gly Lys Phe Ile
                  65                  70                  75

 Lys Thr Pro Pro Gly Val Ser Ala Pro Thr Glu Pro Leu Leu Cys
                  80                  85                  90

 Lys Phe Ala Asp Gly Gly Gln Lys Lys Arg Gln Asn Pro Asn Lys
                  95                 100                 105

 Tyr Ile Pro Asn Gly Arg Pro Trp His Arg Glu Gly Glu Val Arg
                 110                 115                 120

 Leu Ala Gly Met Thr Leu Thr Tyr Asp Pro Thr Thr Ala Ala Ile
                 125                 130                 135

 Gln Asn Gly Phe Tyr Pro Ser Pro Tyr Ser Ile Ala Thr Asn Arg
                 140                 145                 150

 Met Ile Thr Gln Thr Ser Ile Thr Pro Tyr Ile Ala Ser Pro Val
                 155                 160                 165

 Ser Ala Tyr Gln Val Gln Ser Pro Ser Trp Met Gln Pro Gln Pro
                 170                 175                 180

 Tyr Ile Leu Gln His Pro Gly Ala Val Leu Thr Pro Ser Met Glu
                 185                 190                 195

 His Thr Met Ser Leu Gln Pro Ala Ser Met Ile Ser Pro Leu Ala
                 200                 205                 210

 Gln Gln Met Ser His Leu Ser Leu Gly Ser Thr Gly Thr Tyr Met
                 215                 220                 225

 Pro Ala Thr Ser Ala Met Gln Gly Ala Tyr Leu Pro Gln Tyr Ala
                 230                 235                 240

 His Met Gln Thr Thr Ala Val Pro Val Glu Glu Ala Ser Gly Gln
                 245                 250                 255

 Gln Gln Val Ala Val Glu Thr Ser Asn Asp His Ser Pro Tyr Thr
                 260                 265                 270

 Phe Gln Pro Asn Lys Asn Cys Glu Met Tyr Arg Lys Val Phe Leu
                 275                 280                 285

 His Glu Glu Gly Cys Glu Ala Val Ile Gly His Phe Asn Gly Lys
                 290                 295                 300

 Phe Ile Lys Thr Pro Pro Gly Val Ser Ala Pro Thr Glu Pro Leu
                 305                 310                 315

 Leu Cys Lys Phe Ala Asp Gly Gly Gln Lys Lys Arg Gln Asn Pro
                 320                 325                 330

 Asn Lys Tyr Ile Pro Asn Gly Arg Pro Trp His Arg Glu Gly Glu
                 335                 340                 345

 Ala Gly Met Thr Leu Thr Tyr Asp Pro Thr Thr Ala Ala Ile Gln
                 350                 355                 360

 Asn Gly Phe Tyr Pro Ser Pro Tyr Ser Ile Ala Thr Asn Arg Met
                 365                 370                 375

 Ile Thr Gln Thr Ser Ile Thr Pro Tyr Ile Ala Ser Pro Val Ser
                 380                 385                 390

 Ala Tyr Gln Val Gln Ser Pro Ser Trp Met Gln Pro Gln Pro Tyr
                 395                 400                 405

 Ile Leu Gln His Pro Gly Ala Val Leu Thr Pro Ser Met Glu His
                 410                 415                 420

 Thr Met Ser Leu Gln Pro Ala Ser Met Ile Ser Pro Leu Ala Gln
                 425                 430                 435

 Gln Met Ser His Leu Ser Leu Gly Ser Thr Gly Thr Tyr Met Pro
                 440                 445                 450

 Ala Thr Ser Ala Met Gln Gly Ala Tyr Leu Pro Gln Tyr Ala His
                 455                 460                 465

 Met Gln Thr Thr Ala Val Pro Val Glu Glu Ala Ser Gly Gln Gln
                 470                 475                 480

 Gln Val Ala Val Glu Thr Ser Asn Asp His Ser Pro Tyr Thr Phe
                 485                 490                 495

 Gln Pro Asn Lys


<210> 4158
<211> 4444
<212> DNA
<213> Homo sapien

<400> 4158
 aggaatgaaa ggtcataagc cattagaaat agtggcatta ttatgcaata 50

 acaacaccct agctaacctg cttttgtcat ctgtagcact tacaataaag 100

 aatgatgacc ttccaaccct ggacactacc tcgataaagc aaaccagaga 150

 tcctctctac actttctatg gaagccataa aagttgccat caatatatcc 200

 actttcatag ttctatactt ttatactttc tagacttttt tatagacttt 250

 atgatcagat ctttttgtct cagaggatag gttttgcaag attcaaagga 300

 aaatcaaact ccttggttgt tccagctttg aagcttttgc ttcagtaaat 350

 ttgtttaaag aaccagatca cataccattt atcaaattct ttacttaagt 400

 cagaatactt tgcagacata catatttgga aaacaaactg tttcttgttc 450

 actagataga atctgtattg tagtaagaaa ctacttacaa ggtggctttc 500

 tttctgcttt gttactctat gtattactca ataatatatg tatggtcaca 550

 ggttcctgga gttgttttat ttctttatga cagacacatg agtatgcacc 600

 tctctctaat cctctgatgt cactgcagct tcagtctctc tcactctgtt 650

 tttgagtgcc ttcaaaatgc cagcatcctg gaacattctt ttcctgatct 700

 aaatcctacc tctgactatt tcattatcca tgaatattgg aattcaccca 750

 tattccaatg ggcttaactc tacaaactag ctaaaacctt ggacaagaat 800

 ttgaccgtat ttctagtttt gttcctccat gtcattttta ggttatattt 850

 ttaactttta tttatatctt atttcttcac atatttcgtc tctctgttga 900

 aagattttat ccttatttga ctcttcactt tttttacttt caccagaaat 950

 ttgacgttcc tttaaaatta aaggtcattg aatgtctttt gaacaccttt 1000

 ttctcaactg aagtcttcct gaatgcctcc cctttctgat gaaaggatcc 1050

 tgagtgctgc tgttgctctg ccctgttccc atgtgcccac tcccttccgt 1100

 acacattttg caagactata ctctttattt tagtcaaatt aatttaaaat 1150

 tgctccctgg gtttctgctc tctcatggcc ctgtccctca aaaacttctg 1200

 tttacttttt ctagctgttt tcatctaatt tgtttaaaat gtatgatgga 1250

 tccataatat atgaaggatg taatgaaaag gaggttgcag tgttttatat 1300

 aatatgatcg agcacctccg tgatgaaaca tttagcaatt ggctagtcct 1350

 tcacagccag agtggaagtt tgtgctgtgg acaggtcttt ttactccctt 1400

 ccagttctcc tccaaaactg gacgaaaaag gaaaaaaaaa aagaactctt 1450

 tcaaatgagg agatttgatt gcattttttt aggtgaatga aagcttggag 1500

 ttgagcattt gggccttagt cagcattttt cctttctgac ttaaaatctc 1550

 atgtcctttt ccttaaagtt aatagtactc aggtttttaa gactaataac 1600

 cacacaaggt gggtatctaa gaaggcagct gttaatacat tctccatctt 1650

 tcctgtctgg caacaggaaa gatattattg gtgagatagt gcaaaattgt 1700

 gagaattggt tatgttcgat gatgaataaa ttcaagattt ttgaaggctt 1750

 cactgctatt tgggatggga aggtgagttt acaaaatgaa aaaggtagat 1800

 ttttatgtta cagaaatcag taacgggttt cttgttgtgt taattacctt 1850

 tcacttgatt tgccatgatg tttcttcctc attattgatc tagaagtttg 1900

 cctcttggat agtaactagc aacttagtat ctactttaaa atttgtggct 1950

 tttctcttca gggtcccagg ccataaaaca acggagagct gtacttgctt 2000

 gtcacttgga ggaaccacat ccttgagaca gcctgctgtc ttgtatgtct 2050

 tcagtaggaa acttctgaca cacacattca agggagttcc tgcccctgag 2100

 aagtgttccc atagctttcc agtcgcaggt tactttcaca ctacgtcagc 2150

 ttctctggtg agatcaggga tgttacatat tacttgaaaa tgatttcata 2200

 ggaagtgagg atggggcaag aaaggaggta gaagctgaat tttgcttaac 2250

 ttcagaagga aatctgatac ttgccttggc tagttctgat caactaaaga 2300

 gcctgtgtct gtactggatg tgccaaagag tcaagttgtt tctggaatat 2350

 ccagctcctc tgaatgaaca cagcttcctc cctacctgtc ttttatgggt 2400

 gaaaagggac cgtctgatga gcatgataga catcctgtac aggactcaag 2450

 actgtttcat tgcatttgaa agttggtggg aagtatttta ttctgctaga 2500

 gctcctaacc ctcctagaaa tatcttttca tgctctatta attcaattca 2550

 ttagtttaaa aagaaacagt gtgacataat tttggtgttt acttcttaag 2600

 ttgtctcccc aagggcatat atgtagcctc tgaaaatggg atgatttctt 2650

 ctcaatcttc cataaatttg aatatgcatt ttattcattt cttgacatgg 2700

 gctgtgtgac tgttttccat cagcagttct ggctttgtcc acaagggagc 2750

 aataaagtac gttagcttta ttctcaacct tctaaagaaa gatcccactt 2800

 ttaaatctct tctggaatag cctcttagct caaagcttat tcatgtattt 2850

 tgattattta agaaattttc ccttattaca aagtccagtc gtcgttcatc 2900

 cctcatgatg ccaagcaatg attgatgtgt gggtgtggag tccttgtggg 2950

 tcaggcatct taattaatta gactttttac atattgatga tccccagatt 3000

 gaaagccagg accttcccat aggggcgcct ttgtgtgcta aaggcagagc 3050

 aggcaggctt ctccactcct atctcctccg caggccacca ccatcacatc 3100

 tataggagga acaagagcac tgggggaact ctggagtatg agtaaggaaa 3150

 tgcttctcac cttctctgct ccaaagagat atctgttaca tcagggaaca 3200

 agtcctctag gtcaggcact tcctcctgac cagtgcaacg ggcactccag 3250

 gttagaaact gtgtgtgctc cctctctgtc agttacttgt ctaagggctc 3300

 ctatccgtgg tcatcagctc tctggccatg agttctgttt gtgcttattg 3350

 cagcagcatc ttcacaacaa acaggtcagt aatcaacctg ggaagggaaa 3400

 agacgacagt aaatattacc ccctgtagag ccgggaggca tttacacctg 3450

 gaatggcctt cttaactgat ttctgcctgg ccacctcacc cccagccaag 3500

 tctgaacctg agcaatacca ggcacagaga ggtgtctact tgtaactcca 3550

 acacttgaca aaaaacaaaa ctgaagctgt gattggttta ggcagcaagt 3600

 ggccaggtgc aacttgtttg tttttatttt tgttttcccc aacagtactg 3650

 agatcacttg cacttttcct catttcttaa gaaaatccag tttgcttgcc 3700

 atgacttgtt tagcgttagg tttacaaagc ttgttgttga atgttgaata 3750

 tttgtccaaa ggagtttgac aaaatagaag ctgcttggtc cctgttctgc 3800

 ctgctaggtc ataaggatga aggccatgtg gctggggtac ttatgtcaag 3850

 tccagaatgg ggcagtgtcc ctctcctacc tctctgcgga gacgcaattg 3900

 aaggtcaagt agactcagtg tagggcaggc agctgtcatg ctgcaaagaa 3950

 gtttagagga gtctttgggt tggggaggtg acaggtaggt aggacaggat 4000

 ctcttaagat gggaaagata ctggggagag gagggctgct tggccccagg 4050

 gaactgcagt gaggtggaac tgagctccgc tcctgaatct ccaaaggagc 4100

 ccatgctgcc cggcttccct gagtcatttt ttccagcatc ctgtcagatc 4150

 cctcaatgta ctgatttccc ccttgtgtta actataccga tattattttt 4200

 ttagcaattg aaatgcactt ttttatttca actcaatcat gattttaagt 4250

 ataaaaaatt tatagattgt taaaactact tttttgtgta tttttaacca 4300

 ctcaatgtag cattgtatat tttattcttg tgagactctg gtacaggtgt 4350

 gccgcctaat gatttttctg agatgctggg cctttggatg tgtacggtaa 4400

 ccaacttaat gctaatgttc aaagtacaaa acaaaaaaaa gggg 4444

<210> 4159
<211> 5423
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 66, 418, 578, 5390, 5401, 5404, 5407, 5409, 5415
<223> Unknown base

<400> 4159
 taatattgtt gctgatattt tgcataatgg ctgcaattat ttaatgttta 50

 attgggtttg atcaantgag attcagcaat tcacaagtgc attaatataa 100

 ccagaactgg tggcacttaa aatgataatg attaacttat attgcatgtt 150

 ctcttccttt cacttttttc agtttctaca tttcagaccg agcttgtcag 200

 cttttttgaa aacacatcag tagaaaccaa gattttaaaa tgaagtgtca 250

 agacaaaggc aaaacctgag cagttcctaa aaagatttgc tgttagaaat 300

 tttctttgtg gcagtcattt attaaggatt caactcgtga tacaccaaaa 350

 gaagagttga cttcagagat gtgttccatg ctctctagca caggaatgaa 400

 taaatttata acacctgntt tagcctttgt tttcaaaagc acaaaggaaa 450

 agtgaaaggg aaagagaaac aagtgactga gaagtcttgt taaggaatca 500

 ggttttttct acctggtaaa cattctctat tcttttctca aaagattgct 550

 gtaagaaaaa atgtaagaca aaaaaaanaa aaaaaacaaa caggggcaga 600

 ggcaggcagt agcaagaaag cagagcgtaa catcagctag atggtaacat 650

 gcaatgtcag ctctcttgaa gacatgggaa acctaagtta caccttgggt 700

 taaaattctt caccgtatta gttttgttgc ttcataaaat ttacctaagc 750

 aagtggtctt gcttgcctca aatccaagca gtcttgaaca cttggaggca 800

 attaatgagt atatcttagt caaaagaatt gttggagctt tttattaaag 850

 ctgcagtttc agttctgctt ttggggaatt gtgctatgaa agcagctgcc 900

 aaaataagct catttatttt cttcaatccc actcagtgct cagtcactat 950

 attctgtttc cttttttttt tttcaagttg catatttggt ttccccttat 1000

 gattgggaaa gatgaatttt cagcagaaaa cagtgtttgt tcactttcaa 1050

 agagtgatag tttctaaaac atttagagca ataaatattc atcagaggta 1100

 ccaagtaagc cagcagaaga gttaagggtt agagaaatcc cttatttcat 1150

 gtcttgactc taaaatgatc aaagtacttt tccttgtaat gtggatttct 1200

 tcttatgcgg atatgcaaaa acttcagtta tacgtagtaa tgctagcagg 1250

 taattttagt ggacatttta taacaactgt cactttgttt tgccacatgt 1300

 agagtttgtt cagctatttt ccagatatct ccccacaaaa ggaggcaaag 1350

 ggtaccagct tttcaatgag cattacctat tacttggcaa agatgatgaa 1400

 gactctatta atagttcatt tgataaatgt tgacataacc aacaatagag 1450

 attaggaagt tagttttaag aaatcaatag catatagaca ttaccctcat 1500

 ggagtttgta ttctactact tgaactgatt gtagctataa aagcatagtt 1550

 agatagctga atagttagat cataagcaaa gaaggccaga acacatctct 1600

 tatcaagaaa tcaatgaata gtttatctca tttttaaagc aactttatcc 1650

 ttctttaatt ccttcctttc ttctagtgca aaactactta ataaggttgg 1700

 tgtttaggtt agtgttcaca ccattcctca tctggtgtga attaccttct 1750

 ctttctttac tatttactac caacctagta catgtgttga ctgaattctt 1800

 ttcaaacaat gttgagttat catggtgcac ctaataaatt aacaccacag 1850

 attacagcat ccttgctgat tttctcagca aagccagatt agatggaaat 1900

 aaacaaagaa aatgatccta gagtgaattt ttctagaaaa tatctattat 1950

 gaaccatgct gtttaaagta ttagcttgaa ggtgatggat ccagctattc 2000

 agaaaataac tttcatataa ccatgatttt gcacagtatg aggtcttaaa 2050

 tgtgtggaaa gagataaatt ttttatcatt accacaaacc ccttttaaag 2100

 attcaaaggt ggaagaaagt gatttatttt ttctcttcag catacatata 2150

 taaaagactt gtcagatgtt taatttgggg aggttgataa tgaaacatat 2200

 caacagagta tagtagttat agtagtgttt gtgggtaaat aatttcctgg 2250

 ggtcagacat atataaacat atttgcttca aaatgataaa ggcatgaaat 2300

 cagtcttaaa aattgaaatg ggggtgatgg gggagaaaaa gaagaacaaa 2350

 tttgaagtgc cctttcaaat ctgctggata caagtattga agttttaagt 2400

 catcttattc tgtctgaaag tgtatttttc attctacaat agacccaatc 2450

 aacaagacgt ataacttgag ttgcatgatg ttcagtttat gtaatctact 2500

 gttgggatgg taagaattga tgtaggctgt ggtgtaagaa tgaattaaaa 2550

 tatagtttca ctggcttttc tctacatatc cactatcaca atggctaggt 2600

 ttcctgttgc tcactgttgg attctggaga aaaatttaat gaaagatgat 2650

 atcagaggaa gaataagtgg aggtagagaa gaaaggagtg atagaggagg 2700

 ggaaaaaaac aaaacatatt tttgtgttat ccaaaggagc tttttcctta 2750

 ttctgtcaag cattgagatc ttcttcagct ttcaatgtag ttgctaaata 2800

 caaataatgc tactaggtag tgactaaata tagcaaacac ttcatcagat 2850

 attagaatta ggtcacacta ttgaggttat aatctgaagg ttgtgttaca 2900

 tagaaaccac tttagattat tatcaacttg gactaggctt tattttataa 2950

 tagcatagta agtaatatct attgtgtcat ttcttcaacc attttattct 3000

 aagatccatg aagcttcttg aggccaaata aaataataag tttagacaag 3050

 aagtagattg tgactttttt tcccttagag atactattta ctatctccta 3100

 tcctgatagg tggaaggttt actgaattgg aaattggttg actattagtt 3150

 tttaactaaa atgtgcaata acacattgca gtttcctcaa actagtttcc 3200

 tatgatcatt aaactcattc tcagggttaa gaaaggaatg taaatttctg 3250

 cctcaatttg tacttcatca ataagttttt gaagagtgca gatttttagt 3300

 caggtcttaa aaataaactc acaaatctgg atgcatttct aaattctgca 3350

 aatgtttcct ggggtgactt aacaaggaat aatcccacaa tatacctagc 3400

 tacctaatac atggagctgg ggctcaaccc actgttttta aggatttgcg 3450

 cttacttgtg gctgaggaaa aataagtagt tcgaggaagt agtttttaaa 3500

 tgtgagctta tagatagaaa cagaatatca acttaattat gaaattgtta 3550

 gaacctgttc tcttgtatct gaatctgatt gcaattacta ttgtactgat 3600

 agactccagc cattgcaagt ctcagatatc ttagctgtgt agtgattctt 3650

 gaaattcttt ttaagaaaaa ttgagtagaa agaaataaac cctttgtaaa 3700

 tgaggcttgg cttttgtgaa agatcatccg caggctatgt taaaaggatt 3750

 ttagctcact aaaagtgtaa taatggaaat gtggaaaata tcgtaggtaa 3800

 aggaaactac ctcatgctct gaaggttttg tagaagcaca attaaacatc 3850

 taaaatggct ttgttacacc agagccatct ggtgtgaaga actctatatt 3900

 tgtatgttga gagggcatgg aataattgta ttttgctggc aatagacaca 3950

 ttctttatta tttgcagatt cctcatcaaa tctgtaatta tgcacagttt 4000

 ctgttatcaa taaaacaaaa gaatcctgtt tgtgtggttt catgaaatca 4050

 gcattgttga atgcatgaag taataatgct caaattaaca tttttatgat 4100

 gtgtcaaggt ttctggtcaa gggaagtaaa tgtaggatag tatttttaca 4150

 ccaaaatgac acagagagaa ttgagcacac cagaaagacc agaaaccaca 4200

 ccactggata gagattcaat atgttgtctt tttcaaacat ttggacaaga 4250

 aaaaaatggg catttaaaaa ttcttccttc ccctggttat ggatttatct 4300

 gtagtaaaac ttagctttgt cgtttgagat ttgcacagaa tggggggagt 4350

 agattacctc ttcccattca ttgtcataat ggatctacat cactgataaa 4400

 caccatactt ctatatgtgg ttaactagct ttagaataaa agacacttta 4450

 aaaagtaaaa ggcctagaga tcttcaatga agtgtccctt ttagccaaac 4500

 caggccttgc agaaattgtc ctcaaaagca ccaagggaga acaaagccaa 4550

 gtgcagaatt acccaagggt cacacatttt gtattcattt tcttataatt 4600

 tgcccaaatg atttgaagta cagcaaaacc tgaagttttg caaagagtta 4650

 ctgtaaactg aacttaaaaa tgtcagagtg ctcggtgacc cacttctcca 4700

 gaccctgtca acctgtgaaa atattggcct ttattcagat ctctcaagaa 4750

 gttacgtgca gagtttggaa ggtctaggca aaggttatta gtcaagtgtt 4800

 cttacagtgt caacgctcaa ctcccacaag cgtgagaagg agagacctgt 4850

 cattcctgag ggtgatgaca tacatttact ggagcttata taatttatca 4900

 gataagacag cagtctcctt cagggtagaa agtgtgtttt ctacattgat 4950

 ttagtacaaa acaaaaagaa aaggggatat ttcaaatttt ataattattt 5000

 ttctgctaag ctgattcagt gtgatttaag catatttttc aaatcatgaa 5050

 tctgattcca tatacatatg tgccttatat tgtgataatt tatttttaag 5100

 tgaaatatgc tatcatagcc tgactttatg tatagtggcg acaacttgca 5150

 ggatcgcatt tctgtaacca aacggccgac agctgaggtg tagatgcttc 5200

 ctatggtctg tagaataatc actgggcttg ttctctagct atgtctgtat 5250

 gcaatcgcga cagtgttgat caaaacccat gatcattctc tccaaaggtc 5300

 tttgtcacta agccactagg gattctgaaa agttcgtgag ctgaaacaaa 5350

 taaattgagt tggaagattc atgttgaaaa aaaaagaaan aaaaaaaaaa 5400

 nggncgncnc cgagnaagta gcc 5423

<210> 4160
<211> 16
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 7, 11-13, 15
<223> unknown amino acid

<220>
<221> Unsure
<222> 66, 418, 578, 5390, 5401, 5404, 5407, 5409, 5415
<223> Unknown amino acid

<400> 4160
 Met Leu Lys Lys Lys Glu Xaa Lys Lys Lys Xaa Xaa Xaa Pro Xaa
   1               5                  10                  15

 Lys


<210> 4161
<211> 3910
<212> DNA
<213> Homo sapien

<400> 4161
 gctttctgcc ttctaaagtg caacagtata tatcttgtag aactgtggga 50

 ggagagaaga taatttttct accttactcc atattcttac ttcaaactat 100

 tttgaataga ggttcactga gccattgctg atagactgtg catagctact 150

 agctgtcaca ctattgtagg ttttttggag agattcatag ggaagtgaat 200

 gtaaccagga ataaaggctc tcactttagc tctgggacta tgcagtggat 250

 cttgggaaca aaataagata tctaatctat tttccccatt ctggctagat 300

 tttggttgtt gtgatgctcc tacttcctgt ataggttttt gggatcatgg 350

 tgcaggctag taataggatt cagaattgct tcccttttat atcgaccatg 400

 taagggattc taaaggaggg taaatctcaa agtgctctga aatcatccct 450

 ctaaaatctg tcctgtggtg tgctaagatg tctgttgcct ttttatgtta 500

 agctaaggaa cttgaatgcc ttacctaata actcaactag tagtaagctc 550

 attttgtaaa tatgaaaatg gctgtaagaa gtggcattca tgtatattca 600

 atgttagtca atagaccata gtggcctgga tgctttaaca agccaaattc 650

 cgcaattttt tttccttttt tccccttcat acttgtatga tctcacctga 700

 ccagtgattt cttttcctcc taaccccatg ctaccaccat tttctggaaa 750

 tcaaagagat gtggtagtaa atcatacagt acacacgatc atctgagatc 800

 aatatgagca caaaactcat caagtaggtc tgcctggaat gtatataaaa 850

 aatgtaaata aaaatttgta aattagtgtg aactgtatct tgcatatgag 900

 actgtgtatt gttttgcatt ctcttccctt ttgtagaaat ttttctgtaa 950

 ggaaatgatt cagcttgttg gttttagagt aaaaatagcc aacagttgtg 1000

 gctacacagt gagatcacag gaactggaaa tagggtttgt cggctttggt 1050

 taatgtcagt actcatttat ttagcctctc agtgcttaat aagacttttc 1100

 tttatttttt agttagccgt taggttttgt gaggttagat tcctggaagc 1150

 agtgaattta tacactgtta tattaataga gctccgttct ttgagtcatg 1200

 attccaagct aaaggaaatt aaaaatgtaa tttaataatt tcctattttt 1250

 agggttgtta atttttttct acaaaaaaac cttgaaattt tagatatccc 1300

 aatgtgaatc taatttccat atatacagaa attagacaaa taataagtct 1350

 ttagttcaac ttaagcatat ctcaaatgac ttctctaaat ttaaagttga 1400

 tcatgatagg atcataaaag acagaaaaga cttaagtaat cttgtaatga 1450

 caattatttc catttttgct gaactaaaaa tatttaactt cataaatatg 1500

 ttactacagc ttccagattt aaagaaaaaa agtttccccc actctcaatt 1550

 aaaagttaga accctccact tttaaaatta tacaaatatt tcttttttac 1600

 attacacaga agccttctgt accattttac gaatttctgt cttcataata 1650

 taagtgaaaa tactgtcatt tcaattttct gctttaaatt gtttttaata 1700

 agcattccaa agtgatacag acttaagctt ttaatcaatc agtcattcag 1750

 ttgatagaca aagttagcga tgctttatgc taggaaactt gttgacagta 1800

 acctgtgcga ctttatgcag aagacaaatg ctagtaatta ttatgcacag 1850

 aggaaaaatc attttaagta tgtggtaaag cagcttcatc tttcaaaatt 1900

 gatttgctct ggtttttctt tagtccatta gattccagaa tgtcctttta 1950

 ctgggaattt agttatgtat taagataacc tgttttcagt tctttttgaa 2000

 aagaagacat tatttatatt gaaccacctt attttaaaat ttttaacttt 2050

 tatataccac ttgtgtgatt ccagtgtcat gtcttgggtt tgatgtcgtt 2100

 ggacagaaaa gtgtatcaat tattttaaat gaatttttcc ccatgtttga 2150

 ggcttagtct gtaaatgtgt tgctgtaaca gaaaatactt gggtatgcat 2200

 tacttgaata cttgaaaact gaaattaata agatgtatta cataatgaat 2250

 tagatttctc tgaacagttt ttacactgaa aatcttcatt tctggattgc 2300

 agtttgaaat ggaatgaaga cctgaattat ttgggtagaa aaaattatga 2350

 tagtgcttat aagaactgta aactgtttta aactattttg tgtttgacgc 2400

 atcaaacttc aagttttttg taagtttctc tcctgaaatt ttctttctct 2450

 tctatacttt atgcacttac tatactactg atgtaataaa agagcagggt 2500

 taaaaatatt gtatctgtat tcattgtgaa tcctgtagct tttctagtta 2550

 acaaaaaatc gctttctaaa atactcttaa tcccattgtt ttggttaaca 2600

 tcttacccat ttgttgtatt tcaaatgcca ttaatcattt tagtacaaca 2650

 cctatgttta taaaaatttg aaaacattac atattgtatt taaaactaat 2700

 tagtgaagag taagaaaaaa actagccaac agaattgtag gtgatgcatt 2750

 agttaaattt caaaactcat aataaaggaa ctttcagaga ttggttgaaa 2800

 cccagtggta tccctgtaaa ttagctcctg tgactggaaa agaccccaaa 2850

 aaggcagtag aggagattag tgtttacttg ctgtggttgt ggtgtgctgc 2900

 tacttaatta taggtagtga cacactgaaa ttcttatttg tccaataatc 2950

 tgaagtagtt tcctatattt atctgtacta aattgactat aaattgagtc 3000

 tgcaaagagg aaactttttg actgtactgt atttaggagc ctttgtacag 3050

 cttggtcaaa tttccatgat atgaagtatt tgagttttaa aatatactgt 3100

 tattaaaagg aaaaagacat ggccattatt ccatgtgctt aaatgataat 3150

 ttccttattc agtttcagaa gaaaaagaat gaaattgggt aactgtcatt 3200

 gcgttagctt tatgttgaat tgggaaattg tggcataaag cttaaattcg 3250

 tgtttatcaa atgtgaacca tagtagtata atgctgcttt gtatataatg 3300

 taagtgctac aaatagtctc agcactgaaa atgtattgat acctcttaaa 3350

 tgaatgcaac ttttgatgta ggtgttttgc tatgcctcag aaaatatctg 3400

 tctgagaatt tgttaatctg tttgataatg aagatacttc ctgttttctt 3450

 gtttcatatt ttcatgttca aaatttaagt tttacatttt tactactgtt 3500

 aatttaaata aaatttgttc tgtggataaa atgaggttgg cagtgaagaa 3550

 aattaaaaac agcctcattc atgtaactgg ttaagtaaaa atacattttc 3600

 actatgtgtt cataaacttt taatgaagct gtttgtcttt cagttcaaat 3650

 ataagtgatg tttaggcttt atttctgtta ataaggcttt ttaccattga 3700

 ttaaatgaag gaatgtatct ttttgaagag atttatattc tgtaaataaa 3750

 aattcgttgt aacaataaag ttgagttcta actacagtgt attcataaat 3800

 tttattgtta cttcaactta tttttgaggt tttccttgtg aatatctgca 3850

 aacacaagac tttccaaagt tagtgtataa atgtatatgt ggagtgattc 3900

 tttgaattct 3910

<210> 4162
<211> 42
<212> PRT
<213> Homo sapien

<400> 4162
 Phe Leu Pro Ser Lys Val Gln Gln Tyr Ile Ser Cys Arg Thr Val
   1               5                  10                  15

 Gly Gly Glu Lys Ile Ile Phe Leu Pro Tyr Ser Ile Phe Leu Leu
                  20                  25                  30

 Gln Thr Ile Leu Asn Arg Gly Ser Leu Ser His Cys
                  35                  40

<210> 4163
<211> 2616
<212> DNA
<213> Homo sapien

<400> 4163
 gaccgcgtgc cgggtgtcat ggcggcctgc aggtactgct gctcgtgcct 50

 ccggctccgg cccctgagcg atggtccttt ccttctgcca cggcgggatc 100

 gggcactcac ccagttgcaa gtgcgagcac tatggagtag cgcagggtct 150

 cgagctgtgg ccgtggactt aggcaacagg aaattagaaa tatcttctgg 200

 aaagctggcc agatttgcag atggctctgc tgtagtacag tcaggtgaca 250

 ctgcagtaat ggtcacagcg gtcagtaaaa caaaaccttc cccttcccag 300

 tttatgcctt tggtggttga ctacagacaa aaagctgctg cagcaggtag 350

 aattcccaca aactatctga gaagagaggt tggtacttct gataaagaaa 400

 ttctaacaag tcgaataata gatcgttcaa ttagaccgct ctttccagct 450

 ggctacttct atgatacaca ggttctgtgt aatctgttag cagtagatgg 500

 tgtaaatgag cctgatgtcc tagcaattaa tggcgcttcc gtagccctct 550

 cattatcaga tattccttgg aatggacctg ttggggcagt acgaatagga 600

 ataattgatg gagaatatgt tgttaaccca acaagaaaag aaatgtcttc 650

 tagtacttta aatttagtgg ttgctggagc acctaaaagt cagattgtca 700

 tgttggaagc ctctgcagag aacattttac agcaggactt ttgccatgct 750

 atcaaagtgg gagtgaaata tacccaacaa ataattcagg gcattcagca 800

 gttggtaaaa gaaactggtg ttaccaagag gacacctcag aagttattta 850

 ccccttcgcc agagattgtg aaatatactc ataaacttgc tatggagaga 900

 ctctatgcag tttttacaga ttacgagcat gacaaagttt ccagagatga 950

 agctgttaac aaaataagat tagatacgga ggaacaacta aaagaaaaat 1000

 ttccagaagc cgatccatat gaaataatag aatccttcaa tgttgttgca 1050

 aaggaagttt ttagaagtat tgttttgaat gaatacaaaa ggtgcgatgg 1100

 tcgggatttg acttcactta ggaatgtaag ttgtgaggta gatatgttta 1150

 aaacccttca tggatcagca ttatttcaaa gaggacaaac acaggtgctt 1200

 tgtaccgtta catttgattc attagaatct ggtattaagt cagatcaagt 1250

 tataacagct ataaatggga taaaagataa aaatttcatg ctgcactacg 1300

 agtttcctcc ttatgcaact aatgaaattg gcaaagtcac tggtttaaat 1350

 agaagagaac ttgggcatgg tgctcttgct gagaaagctt tgtatcctgt 1400

 tattccccga gattttcctt tcaccataag agttacatct gaagtcctag 1450

 agtcaaatgg gtcatcttct atggcatctg catgtggcgg aagtttagca 1500

 ttaatggatt caggggttcc aatttcatct gctgttgcag gcgtagcaat 1550

 aggattggtc accaaaaccg atcctgagaa gggtgaaata gaagattatc 1600

 gtttgctgac agatattttg ggaattgaag attacaatgg tgacatggac 1650

 ttcaaaatag ctggcactaa taaaggaata actgcattac aggctgatat 1700

 taaattacct ggaataccaa taaaaattgt gatggaggct attcaacaag 1750

 cttcagtggc aaaaaaggag atattacaga tcatgaacaa aactatttca 1800

 aaacctcgag catctagaaa agaaaatgga cctgttgtag aaactgttca 1850

 ggttccatta tcaaaacgag caaaatttgt tggacctggt ggctataact 1900

 taaaaaaact tcaggctgaa acaggtgtaa ctattagtca ggtggatgaa 1950

 gaaacgtttt ctgtatttgc accaacaccc agtgctatgc atgaggcaag 2000

 agacttcatt actgaaatct gcaaggatga tcaggagcag caattagaat 2050

 ttggagcagt atataccgcc acaataactg aaatcagaga tactggtgta 2100

 atggtaaaat tatatccaaa tatgactgcg gtactgcttc ataacacaca 2150

 acttgatcaa cgaaagatta aacatcctac tgccctagga ttagaagttg 2200

 gccaagaaat tcaggtgaaa tactttggac gtgacccagc cgatggaaga 2250

 atgaggcttt ctcgaaaagt gcttcagtcg ccagctacaa ccgtggtcag 2300

 aactttgaat gacagaagta gtattgtaat gggagaacct atttcacagt 2350

 catcatctaa ttctcagtga tttttttttt taaagagaat tctagaattc 2400

 tattttgtct agggtgatgt gctgtagagc aacattttag tagtatcttc 2450

 cattgtgtag atttctatat aatataaata cattttaatt atttgtacta 2500

 aaatgctcat ttacatgtgc cattttttta attcgagtaa cccatatttg 2550

 tttaattgta tttacattat aaatcaagaa atatttatta ttaaaagtaa 2600

 gtcatttata catctt 2616

<210> 4164
<211> 783
<212> PRT
<213> Homo sapien

<400> 4164
 Met Ala Ala Cys Arg Tyr Cys Cys Ser Cys Leu Arg Leu Arg Pro
   1               5                  10                  15

 Leu Ser Asp Gly Pro Phe Leu Leu Pro Arg Arg Asp Arg Ala Leu
                  20                  25                  30

 Thr Gln Leu Gln Val Arg Ala Leu Trp Ser Ser Ala Gly Ser Arg
                  35                  40                  45

 Ala Val Ala Val Asp Leu Gly Asn Arg Lys Leu Glu Ile Ser Ser
                  50                  55                  60

 Gly Lys Leu Ala Arg Phe Ala Asp Gly Ser Ala Val Val Gln Ser
                  65                  70                  75

 Gly Asp Thr Ala Val Met Val Thr Ala Val Ser Lys Thr Lys Pro
                  80                  85                  90

 Ser Pro Ser Gln Phe Met Pro Leu Val Val Asp Tyr Arg Gln Lys
                  95                 100                 105

 Ala Ala Ala Ala Gly Arg Ile Pro Thr Asn Tyr Leu Arg Arg Glu
                 110                 115                 120

 Val Gly Thr Ser Asp Lys Glu Ile Leu Thr Ser Arg Ile Ile Asp
                 125                 130                 135

 Arg Ser Ile Arg Pro Leu Phe Pro Ala Gly Tyr Phe Tyr Asp Thr
                 140                 145                 150

 Gln Val Leu Cys Asn Leu Leu Ala Val Asp Gly Val Asn Glu Pro
                 155                 160                 165

 Asp Val Leu Ala Ile Asn Gly Ala Ser Val Ala Leu Ser Leu Ser
                 170                 175                 180

 Asp Ile Pro Trp Asn Gly Pro Val Gly Ala Val Arg Ile Gly Ile
                 185                 190                 195

 Ile Asp Gly Glu Tyr Val Val Asn Pro Thr Arg Lys Glu Met Ser
                 200                 205                 210

 Ser Ser Thr Leu Asn Leu Val Val Ala Gly Ala Pro Lys Ser Gln
                 215                 220                 225

 Ile Val Met Leu Glu Ala Ser Ala Glu Asn Ile Leu Gln Gln Asp
                 230                 235                 240

 Phe Cys His Ala Ile Lys Val Gly Val Lys Tyr Thr Gln Gln Ile
                 245                 250                 255

 Ile Gln Gly Ile Gln Gln Leu Val Lys Glu Thr Gly Val Thr Lys
                 260                 265                 270

 Arg Thr Pro Gln Lys Leu Phe Thr Pro Ser Pro Glu Ile Val Lys
                 275                 280                 285

 Tyr Thr His Lys Leu Ala Met Glu Arg Leu Tyr Ala Val Phe Thr
                 290                 295                 300

 Asp Tyr Glu His Asp Lys Val Ser Arg Asp Glu Ala Val Asn Lys
                 305                 310                 315

 Ile Arg Leu Asp Thr Glu Glu Gln Leu Lys Glu Lys Phe Pro Glu
                 320                 325                 330

 Ala Asp Pro Tyr Glu Ile Ile Glu Ser Phe Asn Val Val Ala Lys
                 335                 340                 345

 Glu Val Phe Arg Ser Ile Val Leu Asn Glu Tyr Lys Arg Cys Asp
                 350                 355                 360

 Gly Arg Asp Leu Thr Ser Leu Arg Asn Val Ser Cys Glu Val Asp
                 365                 370                 375

 Met Phe Lys Thr Leu His Gly Ser Ala Leu Phe Gln Arg Gly Gln
                 380                 385                 390

 Thr Gln Val Leu Cys Thr Val Thr Phe Asp Ser Leu Glu Ser Gly
                 395                 400                 405

 Ile Lys Ser Asp Gln Val Ile Thr Ala Ile Asn Gly Ile Lys Asp
                 410                 415                 420

 Lys Asn Phe Met Leu His Tyr Glu Phe Pro Pro Tyr Ala Thr Asn
                 425                 430                 435

 Glu Ile Gly Lys Val Thr Gly Leu Asn Arg Arg Glu Leu Gly His
                 440                 445                 450

 Gly Ala Leu Ala Glu Lys Ala Leu Tyr Pro Val Ile Pro Arg Asp
                 455                 460                 465

 Phe Pro Phe Thr Ile Arg Val Thr Ser Glu Val Leu Glu Ser Asn
                 470                 475                 480

 Gly Ser Ser Ser Met Ala Ser Ala Cys Gly Gly Ser Leu Ala Leu
                 485                 490                 495

 Met Asp Ser Gly Val Pro Ile Ser Ser Ala Val Ala Gly Val Ala
                 500                 505                 510

 Ile Gly Leu Val Thr Lys Thr Asp Pro Glu Lys Gly Glu Ile Glu
                 515                 520                 525

 Asp Tyr Arg Leu Leu Thr Asp Ile Leu Gly Ile Glu Asp Tyr Asn
                 530                 535                 540

 Gly Asp Met Asp Phe Lys Ile Ala Gly Thr Asn Lys Gly Ile Thr
                 545                 550                 555

 Ala Leu Gln Ala Asp Ile Lys Leu Pro Gly Ile Pro Ile Lys Ile
                 560                 565                 570

 Val Met Glu Ala Ile Gln Gln Ala Ser Val Ala Lys Lys Glu Ile
                 575                 580                 585

 Leu Gln Ile Met Asn Lys Thr Ile Ser Lys Pro Arg Ala Ser Arg
                 590                 595                 600

 Lys Glu Asn Gly Pro Val Val Glu Thr Val Gln Val Pro Leu Ser
                 605                 610                 615

 Lys Arg Ala Lys Phe Val Gly Pro Gly Gly Tyr Asn Leu Lys Lys
                 620                 625                 630

 Leu Gln Ala Glu Thr Gly Val Thr Ile Ser Gln Val Asp Glu Glu
                 635                 640                 645

 Thr Phe Ser Val Phe Ala Pro Thr Pro Ser Ala Met His Glu Ala
                 650                 655                 660

 Arg Asp Phe Ile Thr Glu Ile Cys Lys Asp Asp Gln Glu Gln Gln
                 665                 670                 675

 Leu Glu Phe Gly Ala Val Tyr Thr Ala Thr Ile Thr Glu Ile Arg
                 680                 685                 690

 Asp Thr Gly Val Met Val Lys Leu Tyr Pro Asn Met Thr Ala Val
                 695                 700                 705

 Leu Leu His Asn Thr Gln Leu Asp Gln Arg Lys Ile Lys His Pro
                 710                 715                 720

 Thr Ala Leu Gly Leu Glu Val Gly Gln Glu Ile Gln Val Lys Tyr
                 725                 730                 735

 Phe Gly Arg Asp Pro Ala Asp Gly Arg Met Arg Leu Ser Arg Lys
                 740                 745                 750

 Val Leu Gln Ser Pro Ala Thr Thr Val Val Arg Thr Leu Asn Asp
                 755                 760                 765

 Arg Ser Ser Ile Val Met Gly Glu Pro Ile Ser Gln Ser Ser Ser
                 770                 775                 780

 Asn Ser Gln


<210> 4165
<211> 1097
<212> DNA
<213> Homo sapien

<400> 4165
 ggcacgaggc cgaagcttcc ggtggccggc ttagttagga gctatggcta 50

 aacatcatcc tgatttgatc ttttgccgca agcaggctgg tgttgccatc 100

 ggaagactgt gtgaaaaatg tgatggcaag tgtgtgattt gtgactccta 150

 tgtgcgtccc tgcactctgg tgcgcatatg tgatgagtgt aactatggat 200

 cttaccaggg gcgctgtgtg atctgtggag gacctggggt ctctgatgcc 250

 tattattgta aggagtgcac catccaggag aaggacagag atggctgccc 300

 aaagattgtc aatctgggga gctctaagac agacctcttc tatgaacgca 350

 aaaaatacgg cttcaagaag aggtgattgg tgggtggccc cttcctcccc 400

 ccaacatcag tctgctgcag ctgccagaaa acatgcctac tactaccagc 450

 agaaagggag cagagcccag agcatcacca ggagtgcctg ctagtgtact 500

 ggcagcttgc caccccctcc tctcccttca cccagacacg tggtagggat 550

 ggaaaaggat tcttcacaga gcactctggc acaccatatc ggagaaaact 600

 tgatagatta gttaatggtt tttcttgaat tcgagaagca aagatctgtt 650

 ctccatattg gtatgttctc cctcaaccaa gatcttctaa aaagaaataa 700

 tattttagtc ttctgcttga ggaactgact gtgaagcgac gcccagtgaa 750

 aaacatgttc ttgcagcagc tctggtggca gctgtccttg aggaaccttt 800

 ggtgtgtggt gggaagctat cagaacaaga aatgtaggca tttcccgttt 850

 tttttggggg gggggtgggg gggcagggct ctgccctctt gaaaggcatt 900

 tacttgttta acacttgtcc agctacagtg gggtacagta gctggctatt 950

 cacaggcatc atcatagccc actagtctca tattattttc cttttgagaa 1000

 attggaaact ctttctgttg ctattatatt aataaagttg gtgtttattt 1050

 tctggtaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 1097

<210> 4166
<211> 110
<212> PRT
<213> Homo sapien

<400> 4166
 Met Ala Lys His His Pro Asp Leu Ile Phe Cys Arg Lys Gln Ala
   1               5                  10                  15

 Gly Val Ala Ile Gly Arg Leu Cys Glu Lys Cys Asp Gly Lys Cys
                  20                  25                  30

 Val Ile Cys Asp Ser Tyr Val Arg Pro Cys Thr Leu Val Arg Ile
                  35                  40                  45

 Cys Asp Glu Cys Asn Tyr Gly Ser Tyr Gln Gly Arg Cys Val Ile
                  50                  55                  60

 Cys Gly Gly Pro Gly Val Ser Asp Ala Tyr Tyr Cys Lys Glu Cys
                  65                  70                  75

 Thr Ile Gln Glu Lys Asp Arg Asp Gly Cys Pro Lys Ile Val Asn
                  80                  85                  90

 Leu Gly Ser Ser Lys Thr Asp Leu Phe Tyr Glu Arg Lys Lys Tyr
                  95                 100                 105

 Gly Phe Lys Lys Arg
                 110

<210> 4167
<211> 1107
<212> DNA
<213> Homo sapien

<400> 4167
 ctcgaagggt cggagacgaa attcccgccc cagactatga ggccgagccc 50

 ctcggagact ctgcccggga cacggcggga ccgaccgcga gggagcggcg 100

 ccggcggcct cccgtacctg cgctcctcca cctccgcgtc tctctcgagc 150

 tccagcaggt ccagttgctt ggtcacgaag ctctccacag ctgccgaggc 200

 catcgccgcc gccggcctgg gcccctagaa gccgacgtcc cgcttctgcg 250

 ccgggccggt gttacagcgg accggtgttc cccgccgggc ccgtgcgtta 300

 cgcacgcggt tcgcgtcgtt tccgtttccg gccgaggctg cgggaagatg 350

 gcggcggcca tggcagcatc ttccctgacg gtcaccttag ggcggctggc 400

 gtccgcgtgc agccacagca tcctgagacc ttcggggccc ggagcagcct 450

 ccctttggtc tgcttctcga aggttcaatt cacagagcac ttcatatcta 500

 ccaggatatg ttcctaaaac atccctgagt tcaccacctt ggccagaagt 550

 tgttctgcca gacccagttg aggagaccag acaccatgca gaggtcgtga 600

 agaaggtgaa tgagatgatc gtcacggggc agtatggcag gctctttgcc 650

 gtggtgcact ttgccagccg ccagtggaag gtgacctctg aagacctgat 700

 cttaattgga aatgaactag accttgcgtg tggagagaga attcgactgg 750

 agaaggtcct gctggttggg gcagacaact tcacgctgct tggcaagcca 800

 ctcctcggaa aggatcttgt tcgagtagaa gccacagtca ttgaaaagac 850

 agaatcatgg ccaagaatca ttatgagatt caggaaaagg aaaaacttca 900

 agaagaaaag aatcgtcacg accccgcaga ctgtcctccg gataaacagc 950

 attgagattg ctccgtgttt gttgtgatta ccgagttaat acttacaaaa 1000

 ggataaaaat aaactcctgc ttcccaagga aaaaaaatct atgtcgggtg 1050

 cggagaaaga ggtaatgaaa tggcaggaac tcgatagtca agcttatcga 1100

 taccgtc 1107

<210> 4168
<211> 324
<212> PRT
<213> Homo sapien

<400> 4168
 Arg Arg Val Gly Asp Glu Ile Pro Ala Pro Asp Tyr Glu Ala Glu
   1               5                  10                  15

 Pro Leu Gly Asp Ser Ala Arg Asp Thr Ala Gly Pro Thr Ala Arg
                  20                  25                  30

 Glu Arg Arg Arg Arg Pro Pro Val Pro Ala Leu Leu His Leu Arg
                  35                  40                  45

 Val Ser Leu Glu Leu Gln Gln Val Gln Leu Leu Gly His Glu Ala
                  50                  55                  60

 Leu His Ser Cys Arg Gly His Arg Arg Arg Arg Pro Gly Pro Leu
                  65                  70                  75

 Glu Ala Asp Val Pro Leu Leu Arg Arg Ala Gly Val Thr Ala Asp
                  80                  85                  90

 Arg Cys Ser Pro Pro Gly Pro Cys Val Thr His Ala Val Arg Val
                  95                 100                 105

 Val Ser Val Ser Gly Arg Gly Cys Gly Lys Met Ala Ala Ala Met
                 110                 115                 120

 Ala Ala Ser Ser Leu Thr Val Thr Leu Gly Arg Leu Ala Ser Ala
                 125                 130                 135

 Cys Ser His Ser Ile Leu Arg Pro Ser Gly Pro Gly Ala Ala Ser
                 140                 145                 150

 Leu Trp Ser Ala Ser Arg Arg Phe Asn Ser Gln Ser Thr Ser Tyr
                 155                 160                 165

 Leu Pro Gly Tyr Val Pro Lys Thr Ser Leu Ser Ser Pro Pro Trp
                 170                 175                 180

 Pro Glu Val Val Leu Pro Asp Pro Val Glu Glu Thr Arg His His
                 185                 190                 195

 Ala Glu Val Val Lys Lys Val Asn Glu Met Ile Val Thr Gly Gln
                 200                 205                 210

 Tyr Gly Arg Leu Phe Ala Val Val His Phe Ala Ser Arg Gln Trp
                 215                 220                 225

 Lys Val Thr Ser Glu Asp Leu Ile Leu Ile Gly Asn Glu Leu Asp
                 230                 235                 240

 Leu Ala Cys Gly Glu Arg Ile Arg Leu Glu Lys Val Leu Leu Val
                 245                 250                 255

 Gly Ala Asp Asn Phe Thr Leu Leu Gly Lys Pro Leu Leu Gly Lys
                 260                 265                 270

 Asp Leu Val Arg Val Glu Ala Thr Val Ile Glu Lys Thr Glu Ser
                 275                 280                 285

 Trp Pro Arg Ile Ile Met Arg Phe Arg Lys Arg Lys Asn Phe Lys
                 290                 295                 300

 Lys Lys Arg Ile Val Thr Thr Pro Gln Thr Val Leu Arg Ile Asn
                 305                 310                 315

 Ser Ile Glu Ile Ala Pro Cys Leu Leu
                 320

<210> 4169
<211> 2737
<212> DNA
<213> Homo sapien

<400> 4169
 ggaaagacta tgttttaggt gacccgtgtg gcctttttgt tgaggccttt 50

 aggatacaag gcccccacct aaagacgcga ccctcccgta ggaggggggc 100

 agggcccggg ggcgggagca cagcggggcc ccagcctcag gcggcgcgtc 150

 actgagcaca aaggagacaa cagcgaggcg gcagcgggcg ctgatcttcg 200

 ctcgccagcc actcgcaatt gcggttacag acctgcagct ccccctcccc 250

 cagccggccc gcccgccttt ctgtctcctc tctccctccg tactggacgg 300

 ccccggtcca tttccgggct ccggatattt ggtatcgatt ggggccgggg 350

 acgcggagca ggtggccgcg gcggggcagc tgggccgcca gcttggtgcc 400

 tcggggaccg tctcccgctg ctttggtcac cagcccctgc ccgcccgacc 450

 cgctccgttc tccggcctgc gagccctgcc ggccggactt tgcgccgcgt 500

 ccggcgctgc tgctgcgctc ggggccccgc tcggcgccgg cggtgaccgg 550

 gaagcccgcg ttaaaggggc aaccgggacc ctggcccggt atggctgaag 600

 tcagcatcga ccagtccaag ctgcctggag tcaaggaagt atgccgagat 650

 tttgctgtcc tggaggacca caccctggct cacagcctgc aggaacaaga 700

 gattgagcat catttggcat cgaacgttca gcggaaccgt ttggtccagc 750

 atgatctcca ggtggctaag cagctccaag aggaagatct gaaagcgcag 800

 gcccagctcc agaagcgcta caaagacctt gaacaacaag actgtgaaat 850

 tgctcaggaa attcaggaga agctggctat tgaggcagag agacgacgca 900

 ttcaggagaa gaaggatgag gacatagctc gccttttgca agaaaaggag 950

 ttacaggaag agaaaaagag aaagaaacac tttccagagt tccctgcaac 1000

 ccgtgcttat gcagatagtt actattatga agatggagga atgaagccaa 1050

 gagtgatgaa agaagctgta tctactccat cacgaatggc ccacagggat 1100

 caggaatggt atgatgctga aattgccaga aaactgcaag aagaagaact 1150

 tttggctacc caggtggaca tgagagccgc tcaagtagct caagatgaag 1200

 aaatcgctcg acttctaatg gctgaagaaa agaaagctta caaaaaagcc 1250

 aaggagcggg agaaatcatc tttggacaaa agaaagcaag accccgagtg 1300

 gaagccaaaa acagctaaag cagcaaattc caagtcaaaa gagagtgatg 1350

 aacctcacca ttctaagaat gaaaggccag cacggccacc accacctatc 1400

 atgacagatg gtgaagatgc ggattacact cattttacaa accagcagag 1450

 ttccacacgg catttctcaa aatcagagtc ctctcataaa ggttttcatt 1500

 acaaacatta aaaacctagg aatctgcctt gaaaatggac tcactatagc 1550

 aaatattact gggtgataca gaatgaattc tacacttact ttttttctcc 1600

 tgtgtttgca ttcctgggat ttatcctcaa gtgcatttct gaccataagt 1650

 aattttaatt catttcaaat gttttggtta ttcatgatca cttgggcagt 1700

 ataagaaaat gtagcttctg aatattggcc acctctatgc tgcatatact 1750

 tcttgggata tagtatctaa gacctttgta aactgccatt ttgttaggta 1800

 tggagtttgg tatctaggga gtaggcctta tttagcaatt caaattttat 1850

 ggagatgaat gatcaaagtg aaacaatgtt tggatgcaac gcagaataaa 1900

 agaatataag aaatagcttt ttgttgcatt aatgtatgat attttgaagg 1950

 acagagcctt tgctttttgt attctttaag aaaagcacaa ccataaagta 2000

 ttttaaaaaa agaaacactt ggagcaattg aaatatgtta ttctgactag 2050

 atggactgta gaggttttgc atttctcagc cctcctgggg agattggcct 2100

 agatagcatt ctttaacact tcctctgctt ttgcctcagt agcaaggctt 2150

 tcctaagctc ctgggcaatg gaacatttat tagtatttat tgacaaaaat 2200

 ttagttctct gaaattttaa ctcatatata tgaaaaactt tgtattccat 2250

 ctcttctttt tcatttactt gtagagccaa ggaaatggaa ttgaaagatg 2300

 attgcataag taatgatgcc atccttctct ctggctgtag actgaggctt 2350

 ttctcttgct tcaagtcaga gcagtatttg ttgataacct ctcaataatg 2400

 tttggtttac atgccagtaa ttaaattaat tcaacatgaa gttgaatttg 2450

 atgaagtggt catctatcca agtatttggt ttttgttttg ttttgttttg 2500

 ttttttgagt tggagtctcg ccctgtcaca caggctggag tgcagtggtg 2550

 caatcttggc tcactgcaac ctccgccacc tgggctggag caattcccct 2600

 gcctcagcct cccaagtagc tggaattaca ggcatgtgtc accacacccg 2650

 gctaattttt gtatttttag taaagagcgg gtttcaccat gttggccagg 2700

 ctggtctcga acccctgacc tcaagtgatc cacctgc 2737

<210> 4170
<211> 306
<212> PRT
<213> Homo sapien

<400> 4170
 Met Ala Glu Val Ser Ile Asp Gln Ser Lys Leu Pro Gly Val Lys
   1               5                  10                  15

 Glu Val Cys Arg Asp Phe Ala Val Leu Glu Asp His Thr Leu Ala
                  20                  25                  30

 His Ser Leu Gln Glu Gln Glu Ile Glu His His Leu Ala Ser Asn
                  35                  40                  45

 Val Gln Arg Asn Arg Leu Val Gln His Asp Leu Gln Val Ala Lys
                  50                  55                  60

 Gln Leu Gln Glu Glu Asp Leu Lys Ala Gln Ala Gln Leu Gln Lys
                  65                  70                  75

 Arg Tyr Lys Asp Leu Glu Gln Gln Asp Cys Glu Ile Ala Gln Glu
                  80                  85                  90

 Ile Gln Glu Lys Leu Ala Ile Glu Ala Glu Arg Arg Arg Ile Gln
                  95                 100                 105

 Glu Lys Lys Asp Glu Asp Ile Ala Arg Leu Leu Gln Glu Lys Glu
                 110                 115                 120

 Leu Gln Glu Glu Lys Lys Arg Lys Lys His Phe Pro Glu Phe Pro
                 125                 130                 135

 Ala Thr Arg Ala Tyr Ala Asp Ser Tyr Tyr Tyr Glu Asp Gly Gly
                 140                 145                 150

 Met Lys Pro Arg Val Met Lys Glu Ala Val Ser Thr Pro Ser Arg
                 155                 160                 165

 Met Ala His Arg Asp Gln Glu Trp Tyr Asp Ala Glu Ile Ala Arg
                 170                 175                 180

 Lys Leu Gln Glu Glu Glu Leu Leu Ala Thr Gln Val Asp Met Arg
                 185                 190                 195

 Ala Ala Gln Val Ala Gln Asp Glu Glu Ile Ala Arg Leu Leu Met
                 200                 205                 210

 Ala Glu Glu Lys Lys Ala Tyr Lys Lys Ala Lys Glu Arg Glu Lys
                 215                 220                 225

 Ser Ser Leu Asp Lys Arg Lys Gln Asp Pro Glu Trp Lys Pro Lys
                 230                 235                 240

 Thr Ala Lys Ala Ala Asn Ser Lys Ser Lys Glu Ser Asp Glu Pro
                 245                 250                 255

 His His Ser Lys Asn Glu Arg Pro Ala Arg Pro Pro Pro Pro Ile
                 260                 265                 270

 Met Thr Asp Gly Glu Asp Ala Asp Tyr Thr His Phe Thr Asn Gln
                 275                 280                 285

 Gln Ser Ser Thr Arg His Phe Ser Lys Ser Glu Ser Ser His Lys
                 290                 295                 300

 Gly Phe His Tyr Lys His
                 305

<210> 4171
<211> 4051
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1185-1467
<223> Unknown base

<400> 4171
 ccaggtatag agaaaaataa gtctgatatg aggaaaattg cacaatttag 50

 agtagttatg ccgtagagaa aatttccaca aactaggaaa tgtagagagt 100

 tattctatag aatactcaaa agaggaaagt atgtgatttt tggaaacagg 150

 aaaatcttca aacttctttc ttcacttccc tttgtgttta gttgaccctc 200

 caatgtgatc attgcctttg gagtttggga gaggtacggg aagtggcctg 250

 atccctgctt ccatacttca ctcctccatc catccttccc tcccttttcc 300

 cctccagcta aatggacaat tctagccaac attgagtcac tcaataagtc 350

 tcaacagtgg gtgtgtttgc tgagattgtc cagcggttga gcagtttggt 400

 ctcacctccc tcgctagttg agaccaaaaa gagacaaata actttttcat 450

 ggtctttgaa acataatgct tatttcgtgg tcaatggctt taaaaaaatc 500

 tgtttcttgt tttcttcaac aaactcacta gttttccctt aaatgatatt 550

 gtaaaaatta aagtaatctt gaaaatgttt tgacaaaagt aaaattaaag 600

 ggacatcttt tcttgttttg tttttttttt ctatggccac acatgaccgt 650

 tccttcacct ttaagcaaag agagtggttc agatggtttc taagatgcca 700

 acctgacctc gcattctgtc attctaccca gctcttaatt caatttgctt 750

 ccattatcct aacaggcttc tttcttactt agaacttgga aaggctgctg 800

 tatttaatac cctccaacac taacgcagac ttaagatagg tactgtttat 850

 tgaaaaccta ctgagtgaaa tgtgcggttt taggaccttc ataaacatct 900

 catttaatct gtctagcatc ctgtgaaaca gccatgattt cacgttgata 950

 aacaaagaag acaggggtcc cagggatgtg aagcatcttg cccaggcttc 1000

 tgctgctggt gaccagtgta gccaggactc cagcccaggt tttcctgact 1050

 cagaagactg agctttttcc tggatgttat taatagctaa ttgtgtccaa 1100

 gcaaccaagg gccttgagtc tgcttggttc tgcttatggc ctcacatcaa 1150

 gaaatggagc tagtccatgt ctgtagtccc aatgnnnnnn nnnnnnnnnn 1200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1450

 nnnnnnnnnn nnnnnnntca cctttttatg acattccttt ttcttagctt 1500

 aagaaaagaa agctgctaga tgagagtctt agttttcctg cataagacct 1550

 cctttatgaa tagaataaaa gactgtcaaa gtaggctggg cttgggccca 1600

 ggctaatcta tgaaggaagc aagctcgtgt tccttaccta tccttttggt 1650

 gtccattgga ttgtgccccg aagtggcctt tacccttgag ccgtccccag 1700

 ccatggtgct cacacatagg cttttgagct ccttggagct atccagatcc 1750

 tgctcacttt tccttcctga gatcagaaca aatcaccccc ttactcccac 1800

 tccaaacaag gccttgatga taaactaatc cttcctaaaa tgctggtagg 1850

 taaacaagca atgatgaagc attgaacaca ggttaactcc tgacttttgt 1900

 accattgtct attccattac acattaacat gactctgaat gccagatcca 1950

 aacctttgcc caccatctgc ttgtcgtgca acagttgagg cagtaaccag 2000

 gggagattca cttcctgtct tgtccttccc ccagggatca cccccctgct 2050

 gccctctagc agccaagctc agatgagttc cattgttacc ctaggtgtgc 2100

 ccatctcttt ggtagggaag gagaaaggta agaatagcca tcaatgagga 2150

 aggattcttg gagcgaggag ccactgtggt ttttcctgct atttaagatg 2200

 ttgagaccgg ataactttag aaagatacct gcacaaaccc ataaatagtg 2250

 cttttataaa gtttagttca ccggaacctg agttcagtat ttgacattag 2300

 ctttttgtcc aaagagttga agcctgctgg aggtctttgc tcaaataata 2350

 aataccacat atttccaagt gtgttcaggt ataggcacta ggtactgtct 2400

 gtttacttca tgttaggcac attacatgca ttggctaatc aaatcctcat 2450

 caattacata tgtaataatc taaacttgcc tccttgtatt ataaatggaa 2500

 ataatcctgt ttatttaaac gggttttcat gtacctgtag ggattaggaa 2550

 actcaaatgg cctttttaat acctttccct agtttgagct ccctgttctc 2600

 tttaacagat aaaacaacat atttgcttca gcctggaatc tgtttttggt 2650

 gctttggtgc agagacagga aatgggcact cagagtcaca ctggtagttg 2700

 cacactgtat ctacagaggg cgtgtctcat ctgtactctg ctgggttaca 2750

 ggatttcagt aggtatttgt gtccacctga gaattctgtt tattaccttt 2800

 catttgacag tgtctttcct ttctgcagtt gattttgcta gagaggcaat 2850

 tcataaggtg aggtcctgtt catagtatga cttgctttct caatatctcc 2900

 ttcaattttt agtaactctt ggtctatttg gtgtctttaa aaaaaataac 2950

 ctagtaataa agacttcttt taatgtggaa atgtggtctg gtagtaagtt 3000

 atttctttcc acatgtaact gacccaatct ggtttccaaa tgagaagtgt 3050

 gcaggcccca gaggttgaga agccatattt caactgtgaa aaaaatctgc 3100

 ttcctgcatc tgttgaaata tagttgttca tacttgccat cccttatctt 3150

 tcttgtaaca atttgcacag ttcttgccag aataaatgcc attatctgta 3200

 tgtttcaggg agttccccaa tttgatcatt tttgtgtgtg tgtggtgtgt 3250

 gtgtgagaga gagagatact gcagtaaaac atttctaaag gatgaaagct 3300

 cttgtatggc atagatatga attccttcct ctggtaataa ttaggttatt 3350

 cccagaagca cagtgtcatt ctttaaataa aagctttcct gtttaaagct 3400

 tttcaaagga gcagaccacc ttgaagattc cccctagggt tgatatgtgt 3450

 ctaattcatt ttataaaaat tattcttgtc ttcattttaa agctttggct 3500

 atatagtcag aaatgtccta aataacaaac tattttgtat ttaatttagg 3550

 gaagactaaa gggaagaaaa atgaaaactc agtctttatg taagctccaa 3600

 ggatattagg gcttaaaggg cttttctagt tttatgagaa tttgtactac 3650

 tgatttttat atattcctgt ttttgagatg aacagatctc tggggaaatt 3700

 gttgagttac aatggcattt cactgtgatc cctctcaagc tcagatcagt 3750

 tctataaccc aatgacaacc tgtctctttg gtttactgtc ctgtgaaatg 3800

 tcagctcaag tttcccagaa gtcgtgtgtt tatgatgagt cagagtgctt 3850

 ttcctcggtg ggacagttgc tggccctctt aattttggtg tatgtgcttc 3900

 caagtatcta aacctccagt ctgatctgta tatgctatcc taactgttaa 3950

 ttgtattatt gattatgttg attatcttgc ttgaaggttc atacttttca 4000

 atttgataga aataaagttt ttttctgctt atagctagcg aattcaaaaa 4050

 a 4051

<210> 4172
<211> 127
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 17-111
<223> unknown amino acid

<220>
<221> Unsure
<222> 1185-1467
<223> Unknown amino acid

<400> 4172
 Met Ala Ser His Gln Glu Met Glu Leu Val His Val Cys Ser Pro
   1               5                  10                  15

 Asn Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Xaa His Leu Phe Met Thr Phe Leu Phe Leu
                 110                 115                 120

 Ser Leu Arg Lys Glu Ser Cys
                 125

<210> 4173
<211> 2671
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1734-1760
<223> Unknown base

<400> 4173
 cacaatggat tctgtggccc caaatgttaa tagtgccaaa gttgagagac 50

 cctggggtag agacgtgtga tgggaaggaa agaaaattac ctttagagct 100

 gcgcgccgcg gcggcggaag atggctgcgg ccgaggtggc ggacactcag 150

 ctgatgcttg gagtcgggct gatcgtgacc atctttccac cgtagaaaag 200

 gacacaaatg gagaagttct gtgggtgtgg tgttatcctt ccacgacagc 250

 cacattaagg aacctgctgc tgagaaaatg ctgccttaca gatgaaaaca 300

 aacttctcca tccctttgtc tttggtcagt acagaagaac atggttttat 350

 atcacaacaa ttgaagttcc agattcttcc attttgaaaa aggtgactca 400

 tttttctatt gtcctgaccg ccaaagattt taacccagag aagtatgctg 450

 ccttcactag gatattgtgt agaatgtacc tgaaacatgg gagcccagtt 500

 aaaatgatgg agagttatat tgcagttctc acaaagggga tatgccagag 550

 tgaagaaaac ggctctttcc ttagtaagga ttttgatgcc cgaaaggcct 600

 acctggctgg ctccatcaaa gacattgtat ctcagtttgg aatggaaact 650

 gttatcttac acacagcact gatgctaaag aaaagaattg tggtgtatca 700

 ccccaagata gaagcggtcc aggagttcac caggactctg cctgccctgg 750

 tgtggcaccg acaggactgg accatccttc actcttacgt gcacctcaac 800

 gccgatgagc tggaagccct gcagatgtgc acaggttacg tcgctggatt 850

 tgtagacttg gaggtgagca acagaccaga cctctatgat gtgtttgtga 900

 atctggcaga gagtgagatt accattgctc cccttgcaaa agaggccatg 950

 gcaatgggca aactgcacaa agaaatgggt cagctaattg ttcagtctgc 1000

 agaagatcca gagaaatcag agagccacgt tatacaggat attgctctaa 1050

 aaacaagaga aatctttacc aacctagcac cattttcaga agtttcggct 1100

 gatggagaaa agagagtcct taatttggag gcgctaaagc aaaaacgatt 1150

 tccaccagca acagaaaact tcctttatca tctagcagca gccgaacaaa 1200

 tgctgaaaat ctgactgtgt gacagaacgt atcactgatg actgatagaa 1250

 agccctcttt cactctgatt acccactcac tacatgaagt cctgaaaata 1300

 acagagaaac tgttatatct ttttaatgat ttatttgcaa gtattgagat 1350

 ttgacctgaa aaacaatgaa acacatgaac acacttccga ttttctcctc 1400

 gctgattagc ttcctgcctg ctgtcagtgc tggacgaagt gctataacta 1450

 ctttatgtaa cattacagaa cagctagagg tcctggggta agagaaaaaa 1500

 agcacatcac aacaaatgtg aaagccttca ttattacacg ttccagtttg 1550

 tctcgctgtg taggcataag ctaatggttt attttcagaa agctgcctga 1600

 aacgttgctt tgtattcttc taggaagaac tttaattcct cctgaggaac 1650

 tctactttct gagccaaact gctaattttc tgcggaactg tctagaagat 1700

 cattcaagag accctgcagt tgcactttct cgtnnnnnnn nnnnnnnnnn 1750

 nnnnnnnnnn gggttttccc cggcctttga acattttgcc tatgagagtt 1800

 ttgcatatat tttatacttg agtagacaac tttaataatc catatttata 1850

 ctatcgcaga agtaagcatt tggcaaacgt tcagccatta gcactcattt 1900

 aaccctgtta gcaatattct tttgaaaaaa gtgccagtcc ttatgtgata 1950

 aactaagaag cccattgaat ataaaagtgt ataggactga aacagtgacc 2000

 ttatattatt gctaagggaa tatgagatta acttcctaca ggggccaaaa 2050

 ccagagaaag gcttccagca acttcgatga aagtagtttg gccacatgtc 2100

 aagccaattg tttgtattat ttatgtacct ttttcataac tggaattgcc 2150

 aaataagcat ggagatctaa atgatgtact tgttagtgta ttcattcata 2200

 ttgattgtaa aggattattt ttcactcagt actgatgtcc ttggaaatct 2250

 tacctggaaa catgtttgca aaaaacatta ttgggtcttt catctttttc 2300

 ttggtattac atatttgttc aataaaaatt aaacaccctc cctttttttt 2350

 gagtgagggc agggagtacc tgaaataaga caatgtttac taaggcaaat 2400

 aattgaaaat taaatctgca ctttatggaa atgagaaata ttaacatctt 2450

 ttttctcatt tttttgtatt actatattag ctaatgatca aagttgttaa 2500

 aattataaat ttatgatgca gaaataaaat tggtatattt tgatattcaa 2550

 ctacttttag gtgggtgacg aattgtcccc tctttctcta atactgctca 2600

 ttccaaagaa aatggggaaa agataccttt tttcaactgt gagggcgcta 2650

 gggaattatt aaaagacctg t 2671

<210> 4174
<211> 403
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1734-1760
<223> Unknown amino acid

<400> 4174
 Gln Trp Ile Leu Trp Pro Gln Met Leu Ile Val Pro Lys Leu Arg
   1               5                  10                  15

 Asp Pro Gly Val Glu Thr Cys Asp Gly Lys Glu Arg Lys Leu Pro
                  20                  25                  30

 Leu Glu Leu Arg Ala Ala Ala Ala Glu Asp Gly Cys Gly Arg Gly
                  35                  40                  45

 Gly Gly His Ser Ala Asp Ala Trp Ser Arg Ala Asp Arg Asp His
                  50                  55                  60

 Leu Ser Thr Val Glu Lys Asp Thr Asn Gly Glu Val Leu Trp Val
                  65                  70                  75

 Trp Cys Tyr Pro Ser Thr Thr Ala Thr Leu Arg Asn Leu Leu Leu
                  80                  85                  90

 Arg Lys Cys Cys Leu Thr Asp Glu Asn Lys Leu Leu His Pro Phe
                  95                 100                 105

 Val Phe Gly Gln Tyr Arg Arg Thr Trp Phe Tyr Ile Thr Thr Ile
                 110                 115                 120

 Glu Val Pro Asp Ser Ser Ile Leu Lys Lys Val Thr His Phe Ser
                 125                 130                 135

 Ile Val Leu Thr Ala Lys Asp Phe Asn Pro Glu Lys Tyr Ala Ala
                 140                 145                 150

 Phe Thr Arg Ile Leu Cys Arg Met Tyr Leu Lys His Gly Ser Pro
                 155                 160                 165

 Val Lys Met Met Glu Ser Tyr Ile Ala Val Leu Thr Lys Gly Ile
                 170                 175                 180

 Cys Gln Ser Glu Glu Asn Gly Ser Phe Leu Ser Lys Asp Phe Asp
                 185                 190                 195

 Ala Arg Lys Ala Tyr Leu Ala Gly Ser Ile Lys Asp Ile Val Ser
                 200                 205                 210

 Gln Phe Gly Met Glu Thr Val Ile Leu His Thr Ala Leu Met Leu
                 215                 220                 225

 Lys Lys Arg Ile Val Val Tyr His Pro Lys Ile Glu Ala Val Gln
                 230                 235                 240

 Glu Phe Thr Arg Thr Leu Pro Ala Leu Val Trp His Arg Gln Asp
                 245                 250                 255

 Trp Thr Ile Leu His Ser Tyr Val His Leu Asn Ala Asp Glu Leu
                 260                 265                 270

 Glu Ala Leu Gln Met Cys Thr Gly Tyr Val Ala Gly Phe Val Asp
                 275                 280                 285

 Leu Glu Val Ser Asn Arg Pro Asp Leu Tyr Asp Val Phe Val Asn
                 290                 295                 300

 Leu Ala Glu Ser Glu Ile Thr Ile Ala Pro Leu Ala Lys Glu Ala
                 305                 310                 315

 Met Ala Met Gly Lys Leu His Lys Glu Met Gly Gln Leu Ile Val
                 320                 325                 330

 Gln Ser Ala Glu Asp Pro Glu Lys Ser Glu Ser His Val Ile Gln
                 335                 340                 345

 Asp Ile Ala Leu Lys Thr Arg Glu Ile Phe Thr Asn Leu Ala Pro
                 350                 355                 360

 Phe Ser Glu Val Ser Ala Asp Gly Glu Lys Arg Val Leu Asn Leu
                 365                 370                 375

 Glu Ala Leu Lys Gln Lys Arg Phe Pro Pro Ala Thr Glu Asn Phe
                 380                 385                 390

 Leu Tyr His Leu Ala Ala Ala Glu Gln Met Leu Lys Ile
                 395                 400

<210> 4175
<211> 2273
<212> DNA
<213> Homo sapien

<400> 4175
 ttttgatact tctgttaaaa tagataataa ggaaccatat cttaaagtgt 50

 ggaggatctg gcttggcttc tgtttttgat agctctatga aagtgacaga 100

 tttgcatcat gagacttagt ggaatgaatt gggaaattga agggcagccc 150

 agtggctatg gattctattt tctatgggac tgtctacgcc aggctttatt 200

 ttctctttgc tcagataact tctgactaga gtcgacggta ggattataaa 250

 tggtttaaaa tacgtattct caaacctcat tttcagcata taaattttta 300

 agaatcagtg tttaaaggta cgtgaaacca tttgctagat ttttgtccta 350

 gttttttttt taatttaaaa atcttaagtt ttttttagta agcttaagat 400

 gtccagtagt ttatttgcag acagcatttt taaaaagtga atagatgttt 450

 aactgaagtt aaatacaaat ttatgtctgt gtaactcttg gtaagatata 500

 acaaaaccta gacatctaaa ttttttggaa atttttattt taaaagtttg 550

 ttgggaggta aaattgtgtg actttacctt ctggttaata gttttatagt 600

 taagaagaaa gtccagcgaa gtttacttga tctcagttgc actccagaat 650

 aggggattta gttccacttt ggttattttc acttctaccc taaattcata 700

 gtccctgata cttaagcttt acccttggct taccagtttt cattgcagcg 750

 agtaaatggg gagtagcaga gcctttgtta atgtaaattg acaaaaagta 800

 tgtccttttc tagcaggagc agataaactg ataatggtct tagaaatgta 850

 gaaaatgatt ttttgtagac aggatgatct gtctagattg tagcaaatga 900

 tggtacatat tcacaacaaa gttgtgccac tacatttaat aaacagccac 950

 aaacaacaaa aggacaactg gtccccgata taaatggact agctacctgg 1000

 acataatatc cttgtgaggc atccttaaag gacaaattgc agctggtatt 1050

 tgggtgaatg ttgttgctct gtgcctgttg aatgtccatg ctacaagaag 1100

 ttatgagcct tgttctaagt acagatgaac cttgtatttg tgtaatctcc 1150

 caagggagag ctatggttta cattcaattt tttggtcttt ctgctatgaa 1200

 acgtgtttat tttgcctctg tcaatgtgtt tgcaacctta agtaaggaaa 1250

 gggaaaaaaa aaatagccct ctgaactctg atcttttgcc gcttctgtag 1300

 attttgattg tgaagttggg agtgaggaca ttcaaaagcc catggtgaat 1350

 gcatatgcct ttagaatatt gtgcctgttt taaaatgttt gagcttttaa 1400

 aatactttgt taaaacatga atccattttt gtaattgtat aaatactcat 1450

 aactaatttt gaatgctact gattgtgtaa ctgaattttt gtatccaaaa 1500

 atacattctt gagtactact tttcctacct tgaaaatcta tttcatttac 1550

 taaatattgt tttctttatg ctaacttaac tttaaaagga atgttgccaa 1600

 gctgtctctc ctcccccatc acaattgtta gtaaatgaaa tagattttca 1650

 aggtaggaaa agtagtactc aagaatgtat ttttggatac aaaattcagt 1700

 acacaccatc agtagcattc caaattagtt atgagtattt ataccattac 1750

 caaaatggat tcatgtttta acacaagtat tttaaaagct ccaacatttt 1800

 aaaacaggca ccatattcta aaggcatatg cattcaccat gggcttttga 1850

 atgtcctcac tcccaaactt caccatccaa atctacagaa gcggccaaag 1900

 atcagagttc agagggctat tttttttttc cctttcctta cttaaggttg 1950

 caaacacatt gacagaggca aaataaacac gtttcatagc agaaagacca 2000

 aaaattgaat gtaaaccata gctctccctt gggagattac acaaatacaa 2050

 ggttcatctg tacttagtac aaggctcata acttcttgta gcatggacat 2100

 tcaacaggca aagaccaaaa attgaatgta aaccatagct ctcccttggg 2150

 agattacaca aatacaaggt tcatctgtac ttagaacagg ctcataactt 2200

 cttgtagcat ggacattcaa caggcacaga gcaacaacat tcacccaaat 2250

 accagctgca atttgtcatt taa 2273

<210> 4176
<211> 20
<212> PRT
<213> Homo sapien

<400> 4176
 Met Asp Ile Gln Gln Ala Gln Ser Asn Asn Ile His Pro Asn Thr
   1               5                  10                  15

 Ser Cys Asn Leu Ser
                  20

<210> 4177
<211> 5385
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 365-388, 2373-2394, 5010-5049
<223> Unknown base

<400> 4177
 atttggtaat gctgcacaga aattttcaat tggagattcc acagtaagcg 50

 ttttttttct ttgaagattt atgatgcact tattcaatag ctgtcagccg 100

 ttccaccctt ttgaccgtac acattctatt acaatgaatt ttgcagtttt 150

 gcacattttt taaatgtcat taactgttag ggaattttac ttgaatactg 200

 aatacatata atgtttatat taaaaaggac atttgtgtta aaaaggaaat 250

 tagagttgca gtaaactttc aatgctgcac acaaaaaaaa gacatttgat 300

 ttttcagtag aaattgtcct acatgtgctt tattgatttg ctattgaaag 350

 aatagggttt tttgnnnnnn nnnnnnnnnn nnnnnnnnta aatgtgcagt 400

 gttgaatcat ttcttcatag tgctcccccg agttgggact agggcttcaa 450

 tttcacttct taaaaaaaat catcatatat ttgatatgcc cagactgcat 500

 acgattttaa gcggagtaca actactattg taaagctaat gtgaagatat 550

 tattaaaaag gttttttttt ccagaaattt ggtgtcttca aattatacct 600

 tcaccttgac atttgaatat ccagccattt tgtttcttaa tggtataaaa 650

 ttccattttc aataacttat tggtgctgaa attgttcact agctgtggtc 700

 tgacctagtt aatttacaaa tacagattga ataggaccta ctagagcagc 750

 atttatagag tttgatggca aatagattag gcagaacttc atctaaaata 800

 ttcttagtaa ataatgttga cacgttttcc ataccttgtc agtttcattc 850

 aacaattttt aaatttttaa caaagctctt aggatttaca catttatatt 900

 taaacattga tatatagagt attgattgat tgctcataag ttaaattggt 950

 aaagttagag acaactattc taacacctca ccattgaaat ttatatgcca 1000

 ccttgtcttt cataaaagct gaaaattgtt acctaaaatg aaaatcaact 1050

 tcatgttttg aagatagtta taaatattgt tctttgttac aatttcgggc 1100

 accgcatatt aaaacgtaac tttattgttc caatatgtaa catggagggc 1150

 caggtcataa ataatgacat tataatgggc ttttgcactg ttattatttt 1200

 tcctttggaa tgtgaaggtc tgaatgaggg ttttgatttt gaatgtttca 1250

 atgtttttga gaagccttgc ttacatttta tggtgtagtc attggaaatg 1300

 gaaaaatggc attatatata ttatatatat aaatatatat tatacatact 1350

 ctccttactt tatttcagtt accatcccca tagaatttga caagaattgc 1400

 tatgactgaa aggttttcga gtcctaatta aaactttatt tatggcagta 1450

 ttcataatta gcctgaaatg cattctgtag gtaatctctg agtttctgga 1500

 atattttctt agactttttg gatgtgcagc agcttacatg tctgaagtta 1550

 cttgaaggca tcacttttaa gaaagcttac agttgggccc tgtaccatcc 1600

 caagtccttt gtagctcctc ttgaacatgt ttgccatact tttaaaaggg 1650

 tagttgaata aatagcatca ccattctttg ctgtggcaca ggttataaac 1700

 ttaagtggag tttaccggca gcatcaaatg tttcagcttt aaaaaataaa 1750

 agtagggtac aagtttaatg tttagttcta gaaattttgt gcaatatgtt 1800

 cataacgatg gctgtggttg ccacaaagtg cctcgtttac ctttaaatac 1850

 tgttaatgtg tcatgcatgc agatggaagg ggtggaactg tgcactaaag 1900

 tgggggcttt aactgtagta tttggcagag ttgccttcta cctgccagtt 1950

 caaaagttca acctgttttc atatagaata tatatactaa aaaatttcag 2000

 tctgttaaac agccttactc tgattcagcc tcttcagata ctcttgtgct 2050

 gtgcagcagt ggctctgtgt gtaaatgcta tgcactgagg atacacaaaa 2100

 ataccaatat gatgtgtaca ggataatgcc tcatcccaat cagatgtcca 2150

 tttgttattg tgtttgttaa caacccttta tctcttagtg ttataaactc 2200

 cacttaaaac tgattaaagt ctcattcttg tcattgtgtg ggtgttttat 2250

 taaatgagag tttataattc aaattgctta agtccattga agttttaatt 2300

 aatgggcagc caaatgtgaa tacaaagttt tcagtttttt tttttcctgc 2350

 tgtccttcaa agcctactgt ttnnnnnnnn nnnnnnnnnn nnnntggcct 2400

 gagagtagag tatctgtcta ctcatgttta attaaggaaa aacacttatt 2450

 tttagggctt tagtcatcac ttcataaatt gtataagcac attaaatagc 2500

 gttctagtcc tgaaaaagtc caagattctt agaaaattgt gcatattttt 2550

 attatgacag atgtttgaag ataattcccc agaatggatt tgatacttta 2600

 gatttcaatt ttgtggcttt tgtctattat tctgtactct gccatcagca 2650

 tatggaaagc ttcatttact catcatgact tgtgccatat aaaaattgat 2700

 atttcggaat agtctaaagg actttttgta cttgaattta atcatgttgt 2750

 ttctaatatt cttaaaagct tgaagactaa agcatatcct ttcaacaaag 2800

 catagtaagg taataagaaa gtgtagtttg tacaagtgtt aaaaaaataa 2850

 agtagacaat gttacagtgg gacttattat ttcaagttta cattttctcc 2900

 atgtaatttt ttaaaaagta aatgaaaaaa tgtgcaataa tgtaaaatat 2950

 gaagtgtatg tgtacacaca ttttattttt cggtatcttg ggtatacgta 3000

 tggttgaaaa ctatactgga gtctaaaagt attctaattt ataagaagac 3050

 attttggtga tgtttgaaaa atagaaatgt gctagttttg tttttatatc 3100

 atgtcctttg tacgttgtaa tatgagctgg cttggttcag taaatgccat 3150

 caccatttcc attgagaatt taaaactcac cagtgtttaa tatgcaggct 3200

 tccaaaggct tatgaaaaaa atcaagaccc ttaaatctag ttaatttgct 3250

 gctaacatga aactctttgg ttcttttatt tttgccagat aattagacac 3300

 acatctaaag cttagtctta aatggcttaa gtgtagctat tgattagtgc 3350

 tgttgctagt tcagaaagaa atgtttgtga atggaaacaa gaatattcag 3400

 tccaaactgt tgtaaggaca gtacctgaaa accaggaaac aggataatgg 3450

 aaaaagtctt ttaaagatga aatgttggag ccaactttct tatagaatta 3500

 attgtatgtg gctatagaaa gcctaatgat tgttgcttat ttttgagagc 3550

 atattattct tttatgacca taatcttgct gtttttccat cttccaaaag 3600

 atcttccttc taatatgtat atcagaatgt gggtagccag tcagacaaat 3650

 tcatattggt tggtagcttt aaaaagtttg taatgtgaag acaggaaagg 3700

 acaaaatagt ttgctttggt ggtagtactc tggttgttaa gctaggtatt 3750

 ttgagactac ttccccatca caacaacaat aaaataatca ctcataatcc 3800

 tatcacctgg agacatagcc atcgttaata tgttagtgac tatacaatca 3850

 tgttttcttc tgtatatcca tgtatattct ttaaaaatga aatttatact 3900

 gtacctgatc tcaaagcttt ttagcttagt atatctgtca tgaatttgta 3950

 ggatgttcca ttgcatcaga aaacggacag tgatttgatt actttctaat 4000

 gccacagatg cagattacat gtagttattg agaatccttt cgaattcagt 4050

 ggcttaatca tgaatgtcta aatattgttg acattaggat gatacatgta 4100

 aattaaagtt acatttgttt agcatagaca agcttaacat tgtagatgtt 4150

 tctcttcaaa aatcatctta aacatttgca tttggaattg tgttaaatag 4200

 aatgtgtgaa acactgtatt agtaaacttc atcacctttc tacttcctta 4250

 tagtttgaac ttttcagttt ttgtagttcc caaacagttg ctcaatttag 4300

 agcaaattaa tttaacacct gccaaaaaaa ggctgctgtt ggcttatcag 4350

 ttgtctttaa attcaaatgc tcatgtgact tttatcacat caaaaaatat 4400

 ttcattaatg attcaccttt agctctgaaa attaccgcgt ttagtaatta 4450

 tagtgggctt ataaaaacat gcaactcttt ttgatagtta tttgagaatt 4500

 ttggtgaaaa atatttagct gagggcagta tagaacttat aaaccaatat 4550

 attgatattt ttaaaacatt tttacatata agtaaactgc catctttgag 4600

 cataactaca tttaaaaata aagctgcata tttttaaatc aagtgtttaa 4650

 caagaattta tattttttat tttttaaaat taaaaataat ttatatttcc 4700

 tctgttgcat gaggattctc atctgtgctt ataatggtta gagattttat 4750

 ttgtgtggaa tgaagtgagg cttgtagtca tggttctagt gtttcagttt 4800

 gccaagtctg tttactgcag tgaaattcat caaatgtttc agtgtggttt 4850

 tctgtagcct atcatttact ggctattttt ttatgtacac ctttaggatt 4900

 ttctgcctac tctatccagt tgtccaaatg atatcctaca ttttacaaat 4950

 gccctttcag tttctatttt ctttttccat taaattgccc tcatgtccta 5000

 atgtgcagtn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna 5050

 ttttcaagag tgctagactt ccaatttgag agattaaata atttaattca 5100

 ggcaaacatt tttcattgga atttcacagt tcattgtaat gaaaatgtta 5150

 atcctggatg acctttgaca tacagtaatg aatcttggat attaatgaat 5200

 ttgttagtag catcttgatg tgtgttttaa tgagttattt tcaaagttgt 5250

 gcattaaacc aaagttggca tactggaagt gtttatatca agttccattt 5300

 ggctactgat ggacaaaaaa tagaaatgcc ttcctatgga gagtattttt 5350

 cctttaaaaa attaaaaagg ttaattattt tgact 5385

<210> 4178
<211> 51
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 365-388, 2373-2394, 5010-5049
<223> Unknown amino acid

<400> 4178
 Met Ser Tyr Phe Gln Ser Cys Ala Leu Asn Gln Ser Trp His Thr
   1               5                  10                  15

 Gly Ser Val Tyr Ile Lys Phe His Leu Ala Thr Asp Gly Gln Lys
                  20                  25                  30

 Ile Glu Met Pro Ser Tyr Gly Glu Tyr Phe Ser Phe Lys Lys Leu
                  35                  40                  45

 Lys Arg Leu Ile Ile Leu
                  50

<210> 4179
<211> 2331
<212> DNA
<213> Homo sapien

<400> 4179
 aaaaacaagc tcagcgatgg cggctccaga aggcagcggt ctaggcgagg 50

 acgcccggct ggaccaggag accgcccagt ggctgcgctg ggacaagaat 100

 tccttaactt tggaggcagt gaaacgacta atagcagaag gtaataaaga 150

 agaactacga aaatgttttg gggcccgaat ggagtttggg acagctggcc 200

 tccgagctgc tatgggacct ggaatttctc gtatgaatga cttgaccatc 250

 atccagacta cacagggatt ttgcagatac ctggaaaaac aattcagtga 300

 cttaaagcag aaaggcatcg tgatcagttt tgacgcccga gctcatccat 350

 ccagtggggg tagcagcaga aggtttgccc gacttgctgc aaccacattt 400

 atcagtcagg ggattcctgt gtacctcttt tctgatataa cgccaacccc 450

 ctttgtgccc ttcacagtat cacatttgaa actttgtgct ggaatcatgg 500

 taactgcatc tcacaatcca aagcaggata atggttataa ggtctattgg 550

 gataatggag ctcagatcat ttctcctcac gataaaggga tttctcaagc 600

 tattgaagaa aatctagaac cgtggcctca agcttgggac gattctttaa 650

 ttgatagcag tccacttctc cacaatccga gtgcttccat caataatgac 700

 tactttgaag accttaaaaa gtactgtttc cacaggagcg tgaacaggga 750

 gacaaaggtg aagtttgtgc acacctctgt ccatggggtg ggtcatagct 800

 ttgtgcagtc agctttcaag gcttttgacc ttgttcctcc tgaggctgtt 850

 cctgaacaga aagatccgga tcctgagttt ccaacagtga aatacccgaa 900

 tcccgaagag gggaaaggtg tcttgacttt gtcttttgct ttggctgaca 950

 aaaccaaggc cagaattgtt ttagctaacg acccggatgc tgatagactt 1000

 gctgtggcag aaaagcaaga cagtggtgaa tggagggtgt tttcaggcaa 1050

 tgagttgggg gccctcctgg gctggtggct ttttacatct tggaaagaga 1100

 agaaccagga tcgcagtgct ctcaaagaca cgtacatgtt gtccagcacc 1150

 gtctcctcca aaatcttgcg ggccattgcc ttaaaggaag gttttcattt 1200

 tgaggaaaca ttaactggct ttaagtggat gggaaacaga gccaaacagc 1250

 taatagacca ggggaaaact gttttatttg catttgaaga agctattgga 1300

 tacatgtgct gcccttttgt tctggacaaa gatggagtca gtgccgctgt 1350

 cataagtgca gagttggcta gcttcctagc aaccaagaat ttgtctttgt 1400

 ctcagcaact aaaggccatt tatgtggagt atggctacca tattactaaa 1450

 gcttcctatt ttatctgcca tgatcaagaa accattaaga aattatttga 1500

 aaacctcaga aactacgatg gaaaaaataa ttatccaaaa gcttgtggca 1550

 aatttgaaat ttctgccatt agggacctta caactggcta tgatgatagc 1600

 caacctgata aaaaagctgt tcttcccact agtaaaagca gccaaatgat 1650

 caccttcacc tttgctaatg gaggcgtggc caccatgcgc accagtggga 1700

 cagagcccaa aatcaagtac tatgcagagc tgtgtgcccc acctgggaac 1750

 agtgatcctg agcagctgaa gaaggaactg aatgaactgg tcagtgctat 1800

 tgaagaacat tttttccagc cacagaagta caatctgcag ccaaaagcag 1850

 actaaaatag tccagccttg ggtatacttg catttaccta caattaagct 1900

 gggtttaact tgttaagcaa tatttttaag ggccaaatga ttcaaaacat 1950

 cacaggtatt tatgtgtttt acaaagacct acattcctca ttgtttcatg 2000

 tttgaccttt aaggtgaaaa aagaaaatgg ccaaacccaa caaactaaca 2050

 ttcctactaa aaagttgagc ttggacatat tttgaatttt tgtaagtgaa 2100

 gatttttaaa ctgactaact taaaaaaata gattgtaatt gatgtgcctt 2150

 aatttgcata aatcataaat gtatgtcctc tctgtaattg ttttaatgtg 2200

 tgcttgaaat atccagaaaa cctatggagt tagtaaattc tgggctgtca 2250

 tatgtaggat agccactttt taggtatatg tacatttata tttctatcaa 2300

 ttccttagaa agtaaaataa atgaatagat c 2331

<210> 4180
<211> 612
<212> PRT
<213> Homo sapien

<400> 4180
 Met Ala Ala Pro Glu Gly Ser Gly Leu Gly Glu Asp Ala Arg Leu
   1               5                  10                  15

 Asp Gln Glu Thr Ala Gln Trp Leu Arg Trp Asp Lys Asn Ser Leu
                  20                  25                  30

 Thr Leu Glu Ala Val Lys Arg Leu Ile Ala Glu Gly Asn Lys Glu
                  35                  40                  45

 Glu Leu Arg Lys Cys Phe Gly Ala Arg Met Glu Phe Gly Thr Ala
                  50                  55                  60

 Gly Leu Arg Ala Ala Met Gly Pro Gly Ile Ser Arg Met Asn Asp
                  65                  70                  75

 Leu Thr Ile Ile Gln Thr Thr Gln Gly Phe Cys Arg Tyr Leu Glu
                  80                  85                  90

 Lys Gln Phe Ser Asp Leu Lys Gln Lys Gly Ile Val Ile Ser Phe
                  95                 100                 105

 Asp Ala Arg Ala His Pro Ser Ser Gly Gly Ser Ser Arg Arg Phe
                 110                 115                 120

 Ala Arg Leu Ala Ala Thr Thr Phe Ile Ser Gln Gly Ile Pro Val
                 125                 130                 135

 Tyr Leu Phe Ser Asp Ile Thr Pro Thr Pro Phe Val Pro Phe Thr
                 140                 145                 150

 Val Ser His Leu Lys Leu Cys Ala Gly Ile Met Val Thr Ala Ser
                 155                 160                 165

 His Asn Pro Lys Gln Asp Asn Gly Tyr Lys Val Tyr Trp Asp Asn
                 170                 175                 180

 Gly Ala Gln Ile Ile Ser Pro His Asp Lys Gly Ile Ser Gln Ala
                 185                 190                 195

 Ile Glu Glu Asn Leu Glu Pro Trp Pro Gln Ala Trp Asp Asp Ser
                 200                 205                 210

 Leu Ile Asp Ser Ser Pro Leu Leu His Asn Pro Ser Ala Ser Ile
                 215                 220                 225

 Asn Asn Asp Tyr Phe Glu Asp Leu Lys Lys Tyr Cys Phe His Arg
                 230                 235                 240

 Ser Val Asn Arg Glu Thr Lys Val Lys Phe Val His Thr Ser Val
                 245                 250                 255

 His Gly Val Gly His Ser Phe Val Gln Ser Ala Phe Lys Ala Phe
                 260                 265                 270

 Asp Leu Val Pro Pro Glu Ala Val Pro Glu Gln Lys Asp Pro Asp
                 275                 280                 285

 Pro Glu Phe Pro Thr Val Lys Tyr Pro Asn Pro Glu Glu Gly Lys
                 290                 295                 300

 Gly Val Leu Thr Leu Ser Phe Ala Leu Ala Asp Lys Thr Lys Ala
                 305                 310                 315

 Arg Ile Val Leu Ala Asn Asp Pro Asp Ala Asp Arg Leu Ala Val
                 320                 325                 330

 Ala Glu Lys Gln Asp Ser Gly Glu Trp Arg Val Phe Ser Gly Asn
                 335                 340                 345

 Glu Leu Gly Ala Leu Leu Gly Trp Trp Leu Phe Thr Ser Trp Lys
                 350                 355                 360

 Glu Lys Asn Gln Asp Arg Ser Ala Leu Lys Asp Thr Tyr Met Leu
                 365                 370                 375

 Ser Ser Thr Val Ser Ser Lys Ile Leu Arg Ala Ile Ala Leu Lys
                 380                 385                 390

 Glu Gly Phe His Phe Glu Glu Thr Leu Thr Gly Phe Lys Trp Met
                 395                 400                 405

 Gly Asn Arg Ala Lys Gln Leu Ile Asp Gln Gly Lys Thr Val Leu
                 410                 415                 420

 Phe Ala Phe Glu Glu Ala Ile Gly Tyr Met Cys Cys Pro Phe Val
                 425                 430                 435

 Leu Asp Lys Asp Gly Val Ser Ala Ala Val Ile Ser Ala Glu Leu
                 440                 445                 450

 Ala Ser Phe Leu Ala Thr Lys Asn Leu Ser Leu Ser Gln Gln Leu
                 455                 460                 465

 Lys Ala Ile Tyr Val Glu Tyr Gly Tyr His Ile Thr Lys Ala Ser
                 470                 475                 480

 Tyr Phe Ile Cys His Asp Gln Glu Thr Ile Lys Lys Leu Phe Glu
                 485                 490                 495

 Asn Leu Arg Asn Tyr Asp Gly Lys Asn Asn Tyr Pro Lys Ala Cys
                 500                 505                 510

 Gly Lys Phe Glu Ile Ser Ala Ile Arg Asp Leu Thr Thr Gly Tyr
                 515                 520                 525

 Asp Asp Ser Gln Pro Asp Lys Lys Ala Val Leu Pro Thr Ser Lys
                 530                 535                 540

 Ser Ser Gln Met Ile Thr Phe Thr Phe Ala Asn Gly Gly Val Ala
                 545                 550                 555

 Thr Met Arg Thr Ser Gly Thr Glu Pro Lys Ile Lys Tyr Tyr Ala
                 560                 565                 570

 Glu Leu Cys Ala Pro Pro Gly Asn Ser Asp Pro Glu Gln Leu Lys
                 575                 580                 585

 Lys Glu Leu Asn Glu Leu Val Ser Ala Ile Glu Glu His Phe Phe
                 590                 595                 600

 Gln Pro Gln Lys Tyr Asn Leu Gln Pro Lys Ala Asp
                 605                 610

<210> 4181
<211> 2055
<212> DNA
<213> Homo sapien

<400> 4181
 ggagggagag gctgaatgtt ggctcggtaa ttgagaggag cggccgctcc 50

 agagcttcct cccggggcgc ccccctcagt ccgtccgcgc ttctcagccg 100

 ccagtctcct ggccgcgcag tccccgcgga cggccgggcc gcggagaccc 150

 tcgcagaaga ggcgctgccg gcggcgagga ctggccggcg gcatccgagg 200

 cgcgcgcccc accgccaccc ccacccgcct gccagccggt ccctccggcc 250

 gccgccatgt cctcctcctc ttcctccccc agggagacgt acgaggagga 300

 ccgggagtac gagagccagg ccaagcgtct caagaccgag gagggggaga 350

 tcgactactc ggccgaggaa ggcgagaacc gccgggaagc gacgccccgg 400

 ggcgggggcg atggcggcgg cggcggccgg agcttctctc agccggaggc 450

 aggtggaagt catcataaag tttctgtttc acccgtcgtc catgttcgag 500

 gactctgtga atctgtggtg gaagcagacc tcgtggaagc gctggaaaaa 550

 tttgggacaa tatgctatgt gatgatgatg ccatttaaac gacaggctct 600

 agtggaattt gaaaacatag atagtgccaa agaatgtgtg acatttgctg 650

 cagatgaacc cgtgtacatt gctggtcaac aggctttttt caactattct 700

 acaagcaaaa ggatcactcg gccaggaaat actgatgatc catcaggagg 750

 caacaaagtt cttctgctct caattcagaa tccgctttat ccaattacag 800

 tggatgtttt atatactgta tgcaaccctg ttggcaaagt gcaacgtatt 850

 gttatattca agagaaatgg gatacaagca atggttgagt ttgaatcagt 900

 cctttgtgcc cagaaagcta aagcagcact caatggagct gatatatatg 950

 ctggatgttg cacactaaaa attgaatatg cacggccaac tcgtctaaat 1000

 gttattagga atgacaatga cagttgggac tacactaaac catatttggg 1050

 aagacgagat agaggaaagg gtcgccagag acaagccatt ttgggagaac 1100

 acccttcttc gtttagacat gatggctatg gatcccatgg tccattattg 1150

 cctttaccaa gtcgttacag aatgggctct cgagatacac ctgaacttgt 1200

 tgcttatcca ttaccacagg cttcttcctc ttacatgcat ggaggaaatc 1250

 cctctggttc agttgtaatg gttagtggat tacatcaact aaaaatgaat 1300

 tgttcaagag tcttcaacct gttctgctta tatggaaata ttgagaaggt 1350

 aaaatttatg aagaccattc ctggtacagc actggtagaa atgggtgatg 1400

 agtatgctgt agaaagagct gtcacacacc ttaataatgt caaattattt 1450

 gggaaaagac ttaatgtttg cgtgtctaaa caacattcag ttgttccaag 1500

 tcaaatattt gagctggagg atggtaccag cagctacaaa gattttgcaa 1550

 tgagcaaaaa taatcgcttt acaagtgctg gccaagcatc taagaatata 1600

 atccagccac cctcctgtgt tttgcattat tataatgttc cattgtgtgt 1650

 cacagaagag accttcacaa agttgtgtaa tgaccatgaa gttcttacat 1700

 tcatcaaata taaagtgttt gatgcaaaac cttcagccaa aacactttct 1750

 gggctattag aatgggagtg caaaactgat gcagtagaag cccttacggc 1800

 actgaatcac tatcagataa gagtgccgaa tggttccaat ccctatacat 1850

 tgaagctttg cttttctaca tcatcccatt tataagaaga gaagagcatg 1900

 ttagaattta tgttcacctt tattacaatt tcaaagctac acttcattaa 1950

 aaaaaaatct aaaatggttg atctcatgtt gccttgctta ctttaagatc 2000

 ctgttctgta ataaacatat tttgccttga gtaaaaaaaa aaaaaaaaaa 2050

 aaaaa 2055

<210> 4182
<211> 542
<212> PRT
<213> Homo sapien

<400> 4182
 Met Ser Ser Ser Ser Ser Ser Pro Arg Glu Thr Tyr Glu Glu Asp
   1               5                  10                  15

 Arg Glu Tyr Glu Ser Gln Ala Lys Arg Leu Lys Thr Glu Glu Gly
                  20                  25                  30

 Glu Ile Asp Tyr Ser Ala Glu Glu Gly Glu Asn Arg Arg Glu Ala
                  35                  40                  45

 Thr Pro Arg Gly Gly Gly Asp Gly Gly Gly Gly Gly Arg Ser Phe
                  50                  55                  60

 Ser Gln Pro Glu Ala Gly Gly Ser His His Lys Val Ser Val Ser
                  65                  70                  75

 Pro Val Val His Val Arg Gly Leu Cys Glu Ser Val Val Glu Ala
                  80                  85                  90

 Asp Leu Val Glu Ala Leu Glu Lys Phe Gly Thr Ile Cys Tyr Val
                  95                 100                 105

 Met Met Met Pro Phe Lys Arg Gln Ala Leu Val Glu Phe Glu Asn
                 110                 115                 120

 Ile Asp Ser Ala Lys Glu Cys Val Thr Phe Ala Ala Asp Glu Pro
                 125                 130                 135

 Val Tyr Ile Ala Gly Gln Gln Ala Phe Phe Asn Tyr Ser Thr Ser
                 140                 145                 150

 Lys Arg Ile Thr Arg Pro Gly Asn Thr Asp Asp Pro Ser Gly Gly
                 155                 160                 165

 Asn Lys Val Leu Leu Leu Ser Ile Gln Asn Pro Leu Tyr Pro Ile
                 170                 175                 180

 Thr Val Asp Val Leu Tyr Thr Val Cys Asn Pro Val Gly Lys Val
                 185                 190                 195

 Gln Arg Ile Val Ile Phe Lys Arg Asn Gly Ile Gln Ala Met Val
                 200                 205                 210

 Glu Phe Glu Ser Val Leu Cys Ala Gln Lys Ala Lys Ala Ala Leu
                 215                 220                 225

 Asn Gly Ala Asp Ile Tyr Ala Gly Cys Cys Thr Leu Lys Ile Glu
                 230                 235                 240

 Tyr Ala Arg Pro Thr Arg Leu Asn Val Ile Arg Asn Asp Asn Asp
                 245                 250                 255

 Ser Trp Asp Tyr Thr Lys Pro Tyr Leu Gly Arg Arg Asp Arg Gly
                 260                 265                 270

 Lys Gly Arg Gln Arg Gln Ala Ile Leu Gly Glu His Pro Ser Ser
                 275                 280                 285

 Phe Arg His Asp Gly Tyr Gly Ser His Gly Pro Leu Leu Pro Leu
                 290                 295                 300

 Pro Ser Arg Tyr Arg Met Gly Ser Arg Asp Thr Pro Glu Leu Val
                 305                 310                 315

 Ala Tyr Pro Leu Pro Gln Ala Ser Ser Ser Tyr Met His Gly Gly
                 320                 325                 330

 Asn Pro Ser Gly Ser Val Val Met Val Ser Gly Leu His Gln Leu
                 335                 340                 345

 Lys Met Asn Cys Ser Arg Val Phe Asn Leu Phe Cys Leu Tyr Gly
                 350                 355                 360

 Asn Ile Glu Lys Val Lys Phe Met Lys Thr Ile Pro Gly Thr Ala
                 365                 370                 375

 Leu Val Glu Met Gly Asp Glu Tyr Ala Val Glu Arg Ala Val Thr
                 380                 385                 390

 His Leu Asn Asn Val Lys Leu Phe Gly Lys Arg Leu Asn Val Cys
                 395                 400                 405

 Val Ser Lys Gln His Ser Val Val Pro Ser Gln Ile Phe Glu Leu
                 410                 415                 420

 Glu Asp Gly Thr Ser Ser Tyr Lys Asp Phe Ala Met Ser Lys Asn
                 425                 430                 435

 Asn Arg Phe Thr Ser Ala Gly Gln Ala Ser Lys Asn Ile Ile Gln
                 440                 445                 450

 Pro Pro Ser Cys Val Leu His Tyr Tyr Asn Val Pro Leu Cys Val
                 455                 460                 465

 Thr Glu Glu Thr Phe Thr Lys Leu Cys Asn Asp His Glu Val Leu
                 470                 475                 480

 Thr Phe Ile Lys Tyr Lys Val Phe Asp Ala Lys Pro Ser Ala Lys
                 485                 490                 495

 Thr Leu Ser Gly Leu Leu Glu Trp Glu Cys Lys Thr Asp Ala Val
                 500                 505                 510

 Glu Ala Leu Thr Ala Leu Asn His Tyr Gln Ile Arg Val Pro Asn
                 515                 520                 525

 Gly Ser Asn Pro Tyr Thr Leu Lys Leu Cys Phe Ser Thr Ser Ser
                 530                 535                 540

 His Leu


<210> 4183
<211> 2021
<212> DNA
<213> Homo sapien

<400> 4183
 agtgttccag ggcggcggtg ggtgtccgct tctctctgct cttcgactgc 50

 accgcactcg cgcgtgaccc tgactccccc tagtcagctc agcggtgctg 100

 ccatggcgtg gcggcggcgc gaagccagcg tcggggctcg cggcgtgttg 150

 gctctggcgt tgctcgccct ggccctgtgc gtgcccgggg cccggggccg 200

 ggctctcgag tggttctcgg ccgtggtaaa catcgagtac gtggacccgc 250

 agaccaacct gacggtgtgg agcgtctcgg agagtggccg cttcggcgac 300

 agctcgccca aggagggcgc gcatggcctg gtgggcgtcc cgtgggcgcc 350

 cggcggagac ctcgagggct gcgcgcccga cacgcgcttc ttcgtgcccg 400

 agcccggcgg ccgaggggcc gcgccctggg tcgccctggt ggctcgtggg 450

 ggctgcacct tcaaggacaa ggtgctggtg gcggcgcgga ggaacgcctc 500

 ggccgtcgtc ctctacaatg aggagcgcta cgggaacatc accttgccca 550

 tgtctcacgc gggaacagga aatatagtgg tcattatgat tagctatcca 600

 aaaggaagag aaattttgga gctggtgcaa aaaggaattc cagtaacgat 650

 gaccataggg gttggcaccc ggcatgtaca ggagttcatc agcggtcagt 700

 ctgtggtgtt tgtggccatt gccttcatca ccatgatgat tatctcgtta 750

 gcctggctaa tattttacta tatacagcgt ttcctatata ctggctctca 800

 gattggaagt cagagccata gaaaagaaac taagaaagtt attggccagc 850

 ttctacttca tactgtaaag catggagaaa agggaattga tgttgatgct 900

 gaaaattgtg cagtgtgtat tgaaaatttc aaagtaaagg atattattag 950

 aattctgcca tgcaagcata tttttcatag aatatgcatt gacccatggc 1000

 ttttggatca ccgaacatgt ccaatgtgta aacttgatgt catcaaagcc 1050

 ctaggatatt ggggagagcc tggggatgta caggagatgc ctgctccaga 1100

 atctcctcct ggaagggatc cagctgcaaa tttgagtcta gctttaccag 1150

 atgatgacgg aagtgatgag agcagtccac catcagcctc ccctgctgaa 1200

 tctgagccac agtgtgatcc cagctttaaa ggagatgcag gagaaaatac 1250

 ggcattgcta gaagccggca ggagtgactc tcggcatgga ggacccatct 1300

 cctagcacac gtgcccactg aagtggcacc aacagaagtt tggcttgaac 1350

 taaaggacat tttatttttt ttactttagc acataatttg tatatttgaa 1400

 aataatgtat attattttac ctattagatt ctgatttgat atacaaagga 1450

 ctaagatatt ttcttcttga agagactttt cgattagtcc tcatatattt 1500

 atctactaaa atagagtgtt taccatgaac agtgtgttgc ttcagactat 1550

 tacaaagaca actggggcag gtactctaat ataaaggaca ggtggtgttt 1600

 ctaaataatt ggctgctatg gttctgtaaa aaccagttaa ttctattttt 1650

 caaggttttt ggcaaagcac atcgatgtta gactagttga agtggaattg 1700

 tataattcaa ttcgataatt gatctcatgg gctttccctg gaggaaaggt 1750

 tttttttgtt gttttttttt taagaacttg aaacttgtaa actgagatgt 1800

 ctgtagcttt tttgcccatc tgtagtgtat gtgaagattt caaaacctga 1850

 gagcactttt tctttgttta gaattatgag aaaggcacta gatgacttta 1900

 ggatttgcat ttttcccttt attgcctcat ttcttgtgac gccttgttgg 1950

 ggagggaaat ctgtttattt tttcctacaa ataaaaagct aagattctat 2000

 atcgcaaaaa aaaaaaaaaa a 2021

<210> 4184
<211> 400
<212> PRT
<213> Homo sapien

<400> 4184
 Met Ala Trp Arg Arg Arg Glu Ala Ser Val Gly Ala Arg Gly Val
   1               5                  10                  15

 Leu Ala Leu Ala Leu Leu Ala Leu Ala Leu Cys Val Pro Gly Ala
                  20                  25                  30

 Arg Gly Arg Ala Leu Glu Trp Phe Ser Ala Val Val Asn Ile Glu
                  35                  40                  45

 Tyr Val Asp Pro Gln Thr Asn Leu Thr Val Trp Ser Val Ser Glu
                  50                  55                  60

 Ser Gly Arg Phe Gly Asp Ser Ser Pro Lys Glu Gly Ala His Gly
                  65                  70                  75

 Leu Val Gly Val Pro Trp Ala Pro Gly Gly Asp Leu Glu Gly Cys
                  80                  85                  90

 Ala Pro Asp Thr Arg Phe Phe Val Pro Glu Pro Gly Gly Arg Gly
                  95                 100                 105

 Ala Ala Pro Trp Val Ala Leu Val Ala Arg Gly Gly Cys Thr Phe
                 110                 115                 120

 Lys Asp Lys Val Leu Val Ala Ala Arg Arg Asn Ala Ser Ala Val
                 125                 130                 135

 Val Leu Tyr Asn Glu Glu Arg Tyr Gly Asn Ile Thr Leu Pro Met
                 140                 145                 150

 Ser His Ala Gly Thr Gly Asn Ile Val Val Ile Met Ile Ser Tyr
                 155                 160                 165

 Pro Lys Gly Arg Glu Ile Leu Glu Leu Val Gln Lys Gly Ile Pro
                 170                 175                 180

 Val Thr Met Thr Ile Gly Val Gly Thr Arg His Val Gln Glu Phe
                 185                 190                 195

 Ile Ser Gly Gln Ser Val Val Phe Val Ala Ile Ala Phe Ile Thr
                 200                 205                 210

 Met Met Ile Ile Ser Leu Ala Trp Leu Ile Phe Tyr Tyr Ile Gln
                 215                 220                 225

 Arg Phe Leu Tyr Thr Gly Ser Gln Ile Gly Ser Gln Ser His Arg
                 230                 235                 240

 Lys Glu Thr Lys Lys Val Ile Gly Gln Leu Leu Leu His Thr Val
                 245                 250                 255

 Lys His Gly Glu Lys Gly Ile Asp Val Asp Ala Glu Asn Cys Ala
                 260                 265                 270

 Val Cys Ile Glu Asn Phe Lys Val Lys Asp Ile Ile Arg Ile Leu
                 275                 280                 285

 Pro Cys Lys His Ile Phe His Arg Ile Cys Ile Asp Pro Trp Leu
                 290                 295                 300

 Leu Asp His Arg Thr Cys Pro Met Cys Lys Leu Asp Val Ile Lys
                 305                 310                 315

 Ala Leu Gly Tyr Trp Gly Glu Pro Gly Asp Val Gln Glu Met Pro
                 320                 325                 330

 Ala Pro Glu Ser Pro Pro Gly Arg Asp Pro Ala Ala Asn Leu Ser
                 335                 340                 345

 Leu Ala Leu Pro Asp Asp Asp Gly Ser Asp Glu Ser Ser Pro Pro
                 350                 355                 360

 Ser Ala Ser Pro Ala Glu Ser Glu Pro Gln Cys Asp Pro Ser Phe
                 365                 370                 375

 Lys Gly Asp Ala Gly Glu Asn Thr Ala Leu Leu Glu Ala Gly Arg
                 380                 385                 390

 Ser Asp Ser Arg His Gly Gly Pro Ile Ser
                 395                 400

<210> 4185
<211> 2288
<212> DNA
<213> Homo sapien

<400> 4185
 aacagagttc agaccttgcc gtcgcgcgcg cgttaagtac caggagaact 50

 acatagccca gcatgcaaca gtctcaactt tttcacggac actacatttc 100

 ccagaaggca gttcgcaccg cagtgttttc tgggatggga accacgccgc 150

 ttcccagtct ctgtgcgagg cgtgaagcgc ggacctttca acaagggctt 200

 tattaattct cacgctgcgg ccctggaaag cgatggaggt ggcggctaat 250

 tgctccctac gggtgaagag acctctgttg gatccccgct tcgagggtta 300

 caagctctct cttgagccgc tgccttgtta ccagctggag cttgacgcag 350

 ctgtggcaga ggtaaaactt cgagatgatc aatatacact ggaacacatg 400

 catgcttttg gaatgtataa ttacctgcac tgtgattcat ggtatcaaga 450

 cagtgtctac tatattgata cccttggaag aattatgaat ttaacagtaa 500

 tgctggacac tgccttagga aaaccacgag aggtgtttcg acttcctaca 550

 gatttgacag catgtgacaa ccgtctttgt gcatctatcc atttctcatc 600

 ttctacctgg gttaccttgt cagatggaac tggaagattg tatgtcattg 650

 gaacaggtga acgtggaaat agcgcttctg aaaaatggga gattatgttt 700

 aatgaagaac ttggggatcc ttttattata attcacagta tctcactgct 750

 aaatgctgaa gaacattcta tagctaccct acttcttcga atagagaaag 800

 aggaattgga tatgaaagga agtggtttct atgtttctct ggagtgggtc 850

 actatcagta agaaaaatca agataataaa aaatatgaaa ttattaagcg 900

 tgatattctc cgtggaaagt cagtgccaca ttatgctgct attgagcctg 950

 atggaaatgg tctaatgatt gtatcctaca agtctttcac atttgttcag 1000

 gctggtcaag atcttgaaga aaatatggat gaagacgtat cagagaaaat 1050

 caaagaacct ctgtattact ggcaacagac tgaagatgat ttgacagtaa 1100

 ccatacggct tccagaagac agtactaagg aggacattca aatacagttt 1150

 ttgcctgatc acatcaacat tgtactgaag gatcaccagt ttttagaagg 1200

 aaaactctat tcatctattg atcatgaaag cagtacatgg ataattaaag 1250

 agagtaatag cttggagatt tccttgatta agaagaatga aggactgacc 1300

 tggccagagc tagtaattgg agataaacaa ggggaactta taagagattc 1350

 agcccagtgt gctgcaatag ctgaacgttt gatgcatttg acctctgaag 1400

 aactgaatcc aaatccagat aaagaaaaac caccttgcaa tgctcaagag 1450

 ttagaagaat gtgatatttt ctttgaagag agctccagtt tatgcagatt 1500

 tgatggcaat acattaaaaa ctactcatgt ggtgaatctt ggaagcaacc 1550

 agtacctttt ctctgtcata gtggatccta aagaaatgcc ctgcttctgt 1600

 ttgcgccatg atgttgatgc cctactctgg caaccacact ccagcaaaca 1650

 agatgatatg tgggagcaca tcgcaacttt caatgcttta ggctatgtcc 1700

 aagcatcaaa gagagacaaa aaattttttg cctgtgctcc aaattactcg 1750

 tatgcagccc tttgtgagtg ccttcgtcga gtattcatct atcgtcagcc 1800

 tgctcccatg tccactgtac tttacaacag aaaggaaggc aggcaagtag 1850

 gacaggttgc taagcagcaa gtagcaagcc tagaaaccaa tgatcctatt 1900

 ttaggatttc aggcaacaaa tgagagatta tttgttctta ctaccaaaaa 1950

 cctcttttta ataaaagtaa atacagagaa ttaattattc taacatattg 2000

 gcctctttgt actggaaaag tattcagtgg tacctggagg tctggacagt 2050

 tatactgtaa cctcttaagt tttaatgtgc taaatatatc ttgtatgatt 2100

 ttttattttt taataacatt ggaaatatat tcaagagatt atgattctgt 2150

 aaagctgtgg aatgaagctg cagatttaga gaacattggc ttctgaaaaa 2200

 aaaaagagtg aagatagtac tagcaagtat acttattttt taaaacaggc 2250

 tagaatctca tgttttatat gaaagatgta caattcag 2288

<210> 4186
<211> 583
<212> PRT
<213> Homo sapien

<400> 4186
 Met Glu Val Ala Ala Asn Cys Ser Leu Arg Val Lys Arg Pro Leu
   1               5                  10                  15

 Leu Asp Pro Arg Phe Glu Gly Tyr Lys Leu Ser Leu Glu Pro Leu
                  20                  25                  30

 Pro Cys Tyr Gln Leu Glu Leu Asp Ala Ala Val Ala Glu Val Lys
                  35                  40                  45

 Leu Arg Asp Asp Gln Tyr Thr Leu Glu His Met His Ala Phe Gly
                  50                  55                  60

 Met Tyr Asn Tyr Leu His Cys Asp Ser Trp Tyr Gln Asp Ser Val
                  65                  70                  75

 Tyr Tyr Ile Asp Thr Leu Gly Arg Ile Met Asn Leu Thr Val Met
                  80                  85                  90

 Leu Asp Thr Ala Leu Gly Lys Pro Arg Glu Val Phe Arg Leu Pro
                  95                 100                 105

 Thr Asp Leu Thr Ala Cys Asp Asn Arg Leu Cys Ala Ser Ile His
                 110                 115                 120

 Phe Ser Ser Ser Thr Trp Val Thr Leu Ser Asp Gly Thr Gly Arg
                 125                 130                 135

 Leu Tyr Val Ile Gly Thr Gly Glu Arg Gly Asn Ser Ala Ser Glu
                 140                 145                 150

 Lys Trp Glu Ile Met Phe Asn Glu Glu Leu Gly Asp Pro Phe Ile
                 155                 160                 165

 Ile Ile His Ser Ile Ser Leu Leu Asn Ala Glu Glu His Ser Ile
                 170                 175                 180

 Ala Thr Leu Leu Leu Arg Ile Glu Lys Glu Glu Leu Asp Met Lys
                 185                 190                 195

 Gly Ser Gly Phe Tyr Val Ser Leu Glu Trp Val Thr Ile Ser Lys
                 200                 205                 210

 Lys Asn Gln Asp Asn Lys Lys Tyr Glu Ile Ile Lys Arg Asp Ile
                 215                 220                 225

 Leu Arg Gly Lys Ser Val Pro His Tyr Ala Ala Ile Glu Pro Asp
                 230                 235                 240

 Gly Asn Gly Leu Met Ile Val Ser Tyr Lys Ser Phe Thr Phe Val
                 245                 250                 255

 Gln Ala Gly Gln Asp Leu Glu Glu Asn Met Asp Glu Asp Val Ser
                 260                 265                 270

 Glu Lys Ile Lys Glu Pro Leu Tyr Tyr Trp Gln Gln Thr Glu Asp
                 275                 280                 285

 Asp Leu Thr Val Thr Ile Arg Leu Pro Glu Asp Ser Thr Lys Glu
                 290                 295                 300

 Asp Ile Gln Ile Gln Phe Leu Pro Asp His Ile Asn Ile Val Leu
                 305                 310                 315

 Lys Asp His Gln Phe Leu Glu Gly Lys Leu Tyr Ser Ser Ile Asp
                 320                 325                 330

 His Glu Ser Ser Thr Trp Ile Ile Lys Glu Ser Asn Ser Leu Glu
                 335                 340                 345

 Ile Ser Leu Ile Lys Lys Asn Glu Gly Leu Thr Trp Pro Glu Leu
                 350                 355                 360

 Val Ile Gly Asp Lys Gln Gly Glu Leu Ile Arg Asp Ser Ala Gln
                 365                 370                 375

 Cys Ala Ala Ile Ala Glu Arg Leu Met His Leu Thr Ser Glu Glu
                 380                 385                 390

 Leu Asn Pro Asn Pro Asp Lys Glu Lys Pro Pro Cys Asn Ala Gln
                 395                 400                 405

 Glu Leu Glu Glu Cys Asp Ile Phe Phe Glu Glu Ser Ser Ser Leu
                 410                 415                 420

 Cys Arg Phe Asp Gly Asn Thr Leu Lys Thr Thr His Val Val Asn
                 425                 430                 435

 Leu Gly Ser Asn Gln Tyr Leu Phe Ser Val Ile Val Asp Pro Lys
                 440                 445                 450

 Glu Met Pro Cys Phe Cys Leu Arg His Asp Val Asp Ala Leu Leu
                 455                 460                 465

 Trp Gln Pro His Ser Ser Lys Gln Asp Asp Met Trp Glu His Ile
                 470                 475                 480

 Ala Thr Phe Asn Ala Leu Gly Tyr Val Gln Ala Ser Lys Arg Asp
                 485                 490                 495

 Lys Lys Phe Phe Ala Cys Ala Pro Asn Tyr Ser Tyr Ala Ala Leu
                 500                 505                 510

 Cys Glu Cys Leu Arg Arg Val Phe Ile Tyr Arg Gln Pro Ala Pro
                 515                 520                 525

 Met Ser Thr Val Leu Tyr Asn Arg Lys Glu Gly Arg Gln Val Gly
                 530                 535                 540

 Gln Val Ala Lys Gln Gln Val Ala Ser Leu Glu Thr Asn Asp Pro
                 545                 550                 555

 Ile Leu Gly Phe Gln Ala Thr Asn Glu Arg Leu Phe Val Leu Thr
                 560                 565                 570

 Thr Lys Asn Leu Phe Leu Ile Lys Val Asn Thr Glu Asn
                 575                 580

<210> 4187
<211> 6055
<212> DNA
<213> Homo sapien

<400> 4187
 gggtggcggg gggttgcaag tgggaagcct gctgttcagc tgcccgggct 50

 ctccgcctcc ccccaccctg tattgaggct gggtctgggg aacctgtgct 100

 cagcattcca ccccctggag cttgggcttg gtcttccctg cgggtccctg 150

 cgctgacatt caggcgggga gccaggaggc ctgggcgcct ccagagcccg 200

 ccgggggagc cgggcgaggg ttctgggctc tgacggcggg gtcgcagggt 250

 cgcccgcctc ctggacacgt ctgtaggcct agggaagcct gccggcccgg 300

 gaggtacaga gtaggagaag ccagatccca gggcggacaa cgagaagtcg 350

 tcaggctaag aaatggcatt tcaaaaggca gtgaaaggga cgattcttgt 400

 tggaggaggt gctcttgcaa ctgttttagg actttctcag tttgctcatt 450

 acagaaggaa acaaatgaac ctggcctatg ttaaagcagc agactgcatt 500

 tcagaaccag ttaacaggga gcctccttcc agagaagctc agctactgac 550

 tttgcaaaac acatctgaat ttgatatcct tgttattgga ggaggagcaa 600

 caggaagtgg ctgtgcgcta gatgctgtca ccagaggact aaaaacagcc 650

 cttgtagaaa gagatgattt ctcatcaggg accagcagca gaagcactaa 700

 attgatccat ggtggtgtga gatatctgca gaaggccatc atgaagttgg 750

 atattgagca gtataggatg gtaaaagaag cccttcatga gcgtgccaac 800

 ctgctagaaa ttgctcccca tttatcagct ccattgccta taatgcttcc 850

 agtttacaag tggtggcagt taccttacta ctgggtagga atcaagctgt 900

 atgatttggt tgcaggaagc aattgcctaa aaagcagtta tgtcctcagc 950

 aaatcaagag cccttgaaca tttcccaatg ctccagaagg acaaactggt 1000

 aggagcaatt gtctactatg acggacaaca taacgatgca cggatgaacc 1050

 ttgccattgc tctgactgct gccaggtatg gggctgccac agccaattac 1100

 atggaggtag tgagcttgct caagaagaca gacccccaga cagggaaagt 1150

 gcatgtgagc ggcgcacggt gcaaggatgt cctcacaggg caggaatttg 1200

 acgtgagagc caaatgtgtt atcaatgcca cgggaccttt cacggactct 1250

 gtgcgcaaaa tggatgataa agacgcagca gctatctgcc agccaagtgc 1300

 tggtgtccat attgtgatgc ctggttatta cagcccagag agcatgggac 1350

 ttcttgaccc agcgaccagt gatgggcgag ttattttctt cttaccctgg 1400

 caaaagatga cgatcgctgg cactactgat actccaactg atgttacaca 1450

 ccatccaatt ccttcagaag aagatatcaa cttcattttg aatgaagtgc 1500

 gtaattacct gagttgtgat gttgaagtga gaagagggga tgtcctggca 1550

 gcatggagtg gaatccgtcc tcttgttaca gaccccaaat ctgcagatac 1600

 tcagtctatc tcccgaaatc atgttgttga tatcagtgag agtggcctta 1650

 ttactatagc aggtggaaag tggacaactt atcggtctat ggcagaagat 1700

 accataaatg ctgctgtcaa aactcataat ttaaaagcag gaccaagtag 1750

 aacagttggg cttttccttc aagggggtaa agattggagc cccacactct 1800

 acattaggct tgtgcaggat tatggacttg aaagcgaggt ggcacagcat 1850

 cttgccgcca cctatggtga taaggccttt gaggtggcca aaatggcaag 1900

 tgtgactggc aaaaggtggc ctattgttgg agtacgtctt gtgtcagaat 1950

 ttccatatat tgaagcagag gtgaaatatg ggattaagga gtatgcctgc 2000

 actgctgtgg atatgatttc acgtcgtact cgcctggcct ttctaaatgt 2050

 ccaggcagca gaggaagccc tacccaggat tgttgaactg atgggcaggg 2100

 aactgaattg ggatgattat aagaagcagg aacaacttga aacagccagg 2150

 aagtttctat attatgaaat gggctataaa tctcgatcag aacagttaac 2200

 agatcgctct gaaattagcc tactgccttc agacattgac aggtataaga 2250

 agagatttca taagtttgat gcagaccaga aaggctttat taccattgtt 2300

 gatgttcagc gtgtattaga gagtatcaat gtccaaatgg atgaaaatac 2350

 actccatgaa attctaaatg aagttgattt gaataaaaat ggacaggttg 2400

 aactcaatga atttttgcag ctgatgagtg ctattcaaaa aggaagggta 2450

 tctggaagcc ggcttgctat actaatgaaa actgcagaag agaacctcga 2500

 cagaagagtt ccaattccag tggaccgtag ttgtggagga ttgtgagtct 2550

 gggcagtaaa tccacagcca acaaacatag aaacgacaaa tcaccatgta 2600

 acaaccagag atgactgaaa ccactctgaa ataatgaatg tggatagctg 2650

 ccttttttaa cactagaaaa cattccaaaa ctttaaggtg ttggtgtatt 2700

 tgccagcttt atttgctgta ctttatttgt atttgccatt cagtctagct 2750

 tttaagtata tttttttctt tttctcattt tcaatgcaca ttagttttgc 2800

 atctgttttg tgacctgtta gatgtgacac attctctttt tgtttattcc 2850

 cttattctaa atgagttcta aaaacataat attttggcaa aaattgaaaa 2900

 aagctggaga cattttgtga catgcataca gatagcatgt gttattaaaa 2950

 agagttgcct attgaaatga tcgtgtttct ggagaaatta agcttataga 3000

 cagcatgtgt tattaaaaag agttacctat tgaaatgata gtgtttctgg 3050

 agatttctca gccccatctt cctccagctt gtctaccttc ctcatgcaaa 3100

 caatattcca catttttata tctagagcat gactggctaa ctggagaggg 3150

 aaggaaaagt ttagatctgg ttactggagc aagtctcaaa gagaaactct 3200

 gaaagcttcc agaatcacag gtataagata aggatagcat tgacatttgc 3250

 tgggagttac agtgatagtt tcatctcagc agttcatttt tttcttcagt 3300

 cactgctggt tttctttgac tattatagtt gccaggaaga tccttgctct 3350

 tcttacttta aaaccagcat ttaagtggca atttggatgt aataggatga 3400

 gaccaaattt atctaattat tacagtagta atacatttaa gagttaaaaa 3450

 tgtgttttta tatatccaca tatgataaca aaagattcaa ttcccaagcc 3500

 taaattttga agcatgtggt attgtcaaat ctagcttacc atcttttttg 3550

 ggggtacttg caaccatagt aaaggaagat ggaatagact ttagttaact 3600

 ttaattataa ttatatgtta aataaggcac ataaccagtt tccaaggtca 3650

 tcatggttgc ttaaagtctt tccccttctg tactccatgg aaatattctc 3700

 agtaaaccaa aaacaaaaat ggaaaaataa tcaccaaccc ccatcccgac 3750

 acacacacac agtccaaagc aaaagtcagt gtgtattgaa tttaacaagt 3800

 aatgcagttt gggatgcttt tgctacattt tggtggcatt ttaactagtt 3850

 atctgaatat ttattaatcg tacttcctct tgtaaagtta actacttact 3900

 tttttgttgt tgttttttta acatcaggtt ctgtatctaa taggagatgt 3950

 aacactttat ttcatggcag gtttttattg cagagacttg aagtcttagt 4000

 tttttaaact ggcacataaa acactttttg ctgttatttt tatttatgtc 4050

 aatactgcag agtatcttta tgccttattc aagtggattc tgagcctgta 4100

 tgtcacaatg taaacactgg aggttcactc acctacgcac tcacccacca 4150

 cctctgaaag aaacagaaac tgcagagaaa gacagcatct tagctcattt 4200

 tgtttttaaa tgaggtttta gacgcttgcc acttcctaag ggaaatccta 4250

 aaacagagca agtgatgctc ccaggtatca ctgtgaactt ttttctttca 4300

 aagtgtgaat ttttacactg gctttttcat ttttttaaag taattgaagc 4350

 ttgtggcttt acaacttagt gttttttgct atccagataa caagtttcat 4400

 tgtttagaac ccagtgacac ttaataggta gataaattgt cctttaaaat 4450

 atcccagatg atatacacaa tatggtacat ttgtgctctc tctctctgtt 4500

 tttctctctt tctctttcta gttagatcaa gataacgatg acttgtaccc 4550

 tccctgattc tgttacagta gggcccgggc agatctgtgt ttgttaaaca 4600

 ggccttgttt gtgcatgctt tgctatgaat gaagttcctt taaggacaaa 4650

 gaaaagcaca cttttcttct tttgagcata tctgctttta ctttaaatct 4700

 gctaatttct aaaatgtaga gtccttcacc aatcccagag actcaatttg 4750

 gaaatgaact gatttcaagc cgttactgtc aataaagcac cccagcattt 4800

 tgtataagct cttaattaaa cctgtacagc ttctttacct gatttaagaa 4850

 agggagacaa gcaatagggg ggaataagct tcttcaaaat tcattccaag 4900

 cacaaaagaa attttttccc tttgcatata aacttgacat cagttgattc 4950

 tgttggggtc ggggtgggta tgcagggatt gccttttatt atcaagtgat 5000

 ttatttcaag agcctttgag gggattcagg tgaaggaacc cccatctgtg 5050

 ctggagagtt ggatactcct ttaaatagcc cccaccacag tcataacaat 5100

 aatgataatg ctggattatt tgttaagcca aggttgtctg cctcatatcc 5150

 atcatgctgt ttgcaatatt cttgctttca atcaatttat actgagtgta 5200

 actttaggat ttctgctatt aaatgcatgc tctctatcct gcttcagttt 5250

 ctggctttgc tttgtctgtt tcaaaatatg tagcttcctc ttttgtacaa 5300

 caaaaaactc attctcactt ttactaaata tactgtagga gtcatcattg 5350

 atgttatttt tctcttatgt atctgtaaag atttttggca tatgaatgta 5400

 atattaaagt caatgatgct ataacttgcg atgtttgcat catgtcaacc 5450

 tttttgaagg agtgaaaaag ccctactatg tttttaaata gcaagtgtaa 5500

 gctcagtgct agagtggata tacacaccgc atgttttcat atgtggcact 5550

 tttatgtatc atgttgggtt attgttctag actggactgt taaatactat 5600

 gtttgaggct gggttgtcat ttttataact gtcttggtgt tttatggcca 5650

 ttatttatta cttttgatac acagaatgag ctgcatgcat ttatagagca 5700

 ataagaggat gtatttaatg tgccttgttt ttaactgaat aagaactgga 5750

 agcatgaatc aataaaactg attaaaatgg tctatttgct agcattttga 5800

 tgttacttgc agtcagataa ctttgattac tgttgaagtt taaaaaaagt 5850

 ttgaaaatat ttttacaaac tgtgtttttg atgacacaaa agtgaaatat 5900

 ctacagagat agatgtaatt ttataagact gccagaatta tttgtattaa 5950

 tttgttgctg tagcctttag ggcatgactt ctgtatttgt gcaatcctat 6000

 tctacaatta cattcatcct attacaactc aaagaaaaac aaaaagtcga 6050

 cgcgg 6055

<210> 4188
<211> 727
<212> PRT
<213> Homo sapien

<400> 4188
 Met Ala Phe Gln Lys Ala Val Lys Gly Thr Ile Leu Val Gly Gly
   1               5                  10                  15

 Gly Ala Leu Ala Thr Val Leu Gly Leu Ser Gln Phe Ala His Tyr
                  20                  25                  30

 Arg Arg Lys Gln Met Asn Leu Ala Tyr Val Lys Ala Ala Asp Cys
                  35                  40                  45

 Ile Ser Glu Pro Val Asn Arg Glu Pro Pro Ser Arg Glu Ala Gln
                  50                  55                  60

 Leu Leu Thr Leu Gln Asn Thr Ser Glu Phe Asp Ile Leu Val Ile
                  65                  70                  75

 Gly Gly Gly Ala Thr Gly Ser Gly Cys Ala Leu Asp Ala Val Thr
                  80                  85                  90

 Arg Gly Leu Lys Thr Ala Leu Val Glu Arg Asp Asp Phe Ser Ser
                  95                 100                 105

 Gly Thr Ser Ser Arg Ser Thr Lys Leu Ile His Gly Gly Val Arg
                 110                 115                 120

 Tyr Leu Gln Lys Ala Ile Met Lys Leu Asp Ile Glu Gln Tyr Arg
                 125                 130                 135

 Met Val Lys Glu Ala Leu His Glu Arg Ala Asn Leu Leu Glu Ile
                 140                 145                 150

 Ala Pro His Leu Ser Ala Pro Leu Pro Ile Met Leu Pro Val Tyr
                 155                 160                 165

 Lys Trp Trp Gln Leu Pro Tyr Tyr Trp Val Gly Ile Lys Leu Tyr
                 170                 175                 180

 Asp Leu Val Ala Gly Ser Asn Cys Leu Lys Ser Ser Tyr Val Leu
                 185                 190                 195

 Ser Lys Ser Arg Ala Leu Glu His Phe Pro Met Leu Gln Lys Asp
                 200                 205                 210

 Lys Leu Val Gly Ala Ile Val Tyr Tyr Asp Gly Gln His Asn Asp
                 215                 220                 225

 Ala Arg Met Asn Leu Ala Ile Ala Leu Thr Ala Ala Arg Tyr Gly
                 230                 235                 240

 Ala Ala Thr Ala Asn Tyr Met Glu Val Val Ser Leu Leu Lys Lys
                 245                 250                 255

 Thr Asp Pro Gln Thr Gly Lys Val His Val Ser Gly Ala Arg Cys
                 260                 265                 270

 Lys Asp Val Leu Thr Gly Gln Glu Phe Asp Val Arg Ala Lys Cys
                 275                 280                 285

 Val Ile Asn Ala Thr Gly Pro Phe Thr Asp Ser Val Arg Lys Met
                 290                 295                 300

 Asp Asp Lys Asp Ala Ala Ala Ile Cys Gln Pro Ser Ala Gly Val
                 305                 310                 315

 His Ile Val Met Pro Gly Tyr Tyr Ser Pro Glu Ser Met Gly Leu
                 320                 325                 330

 Leu Asp Pro Ala Thr Ser Asp Gly Arg Val Ile Phe Phe Leu Pro
                 335                 340                 345

 Trp Gln Lys Met Thr Ile Ala Gly Thr Thr Asp Thr Pro Thr Asp
                 350                 355                 360

 Val Thr His His Pro Ile Pro Ser Glu Glu Asp Ile Asn Phe Ile
                 365                 370                 375

 Leu Asn Glu Val Arg Asn Tyr Leu Ser Cys Asp Val Glu Val Arg
                 380                 385                 390

 Arg Gly Asp Val Leu Ala Ala Trp Ser Gly Ile Arg Pro Leu Val
                 395                 400                 405

 Thr Asp Pro Lys Ser Ala Asp Thr Gln Ser Ile Ser Arg Asn His
                 410                 415                 420

 Val Val Asp Ile Ser Glu Ser Gly Leu Ile Thr Ile Ala Gly Gly
                 425                 430                 435

 Lys Trp Thr Thr Tyr Arg Ser Met Ala Glu Asp Thr Ile Asn Ala
                 440                 445                 450

 Ala Val Lys Thr His Asn Leu Lys Ala Gly Pro Ser Arg Thr Val
                 455                 460                 465

 Gly Leu Phe Leu Gln Gly Gly Lys Asp Trp Ser Pro Thr Leu Tyr
                 470                 475                 480

 Ile Arg Leu Val Gln Asp Tyr Gly Leu Glu Ser Glu Val Ala Gln
                 485                 490                 495

 His Leu Ala Ala Thr Tyr Gly Asp Lys Ala Phe Glu Val Ala Lys
                 500                 505                 510

 Met Ala Ser Val Thr Gly Lys Arg Trp Pro Ile Val Gly Val Arg
                 515                 520                 525

 Leu Val Ser Glu Phe Pro Tyr Ile Glu Ala Glu Val Lys Tyr Gly
                 530                 535                 540

 Ile Lys Glu Tyr Ala Cys Thr Ala Val Asp Met Ile Ser Arg Arg
                 545                 550                 555

 Thr Arg Leu Ala Phe Leu Asn Val Gln Ala Ala Glu Glu Ala Leu
                 560                 565                 570

 Pro Arg Ile Val Glu Leu Met Gly Arg Glu Leu Asn Trp Asp Asp
                 575                 580                 585

 Tyr Lys Lys Gln Glu Gln Leu Glu Thr Ala Arg Lys Phe Leu Tyr
                 590                 595                 600

 Tyr Glu Met Gly Tyr Lys Ser Arg Ser Glu Gln Leu Thr Asp Arg
                 605                 610                 615

 Ser Glu Ile Ser Leu Leu Pro Ser Asp Ile Asp Arg Tyr Lys Lys
                 620                 625                 630

 Arg Phe His Lys Phe Asp Ala Asp Gln Lys Gly Phe Ile Thr Ile
                 635                 640                 645

 Val Asp Val Gln Arg Val Leu Glu Ser Ile Asn Val Gln Met Asp
                 650                 655                 660

 Glu Asn Thr Leu His Glu Ile Leu Asn Glu Val Asp Leu Asn Lys
                 665                 670                 675

 Asn Gly Gln Val Glu Leu Asn Glu Phe Leu Gln Leu Met Ser Ala
                 680                 685                 690

 Ile Gln Lys Gly Arg Val Ser Gly Ser Arg Leu Ala Ile Leu Met
                 695                 700                 705

 Lys Thr Ala Glu Glu Asn Leu Asp Arg Arg Val Pro Ile Pro Val
                 710                 715                 720

 Asp Arg Ser Cys Gly Gly Leu
                 725

<210> 4189
<211> 1393
<212> DNA
<213> Homo sapien

<400> 4189
 gggagtccct ggtgggaaaa gtccacaatt tcccattgat agctttttac 50

 tgttgtgaaa aagggaagcg tcagccacac aaaagcctgc atgaccgctg 100

 cttcggagaa gctctcgacc ctaactgcag tcactgttac ttggatcaga 150

 tcaagcgcag tgactttttg ggattcagtg gttattctcc acacttcgta 200

 gccacttcga ccaactctga gcacaaaatg cagccatcct ctatgcagca 250

 agccctgccc agtcagtggc cctactggac agatccaagg ccagccctgg 300

 ttccctgctg cagccaccgt cctgacgttc atcggagcag gccggggcct 350

 ggccttcccg gcacaagtgg ctgttctgac aggcccccag tttgtcccat 400

 ctgaactgct gggaggtttc cgggtggcca gaggagcaaa gctgccttcc 450

 aagtgcctgt ctgtgcctgg gagaacagag caggagcgtc gtgcggtcca 500

 ccgcgcagtg catggcgatt ccaagcgctg aacaactccc ctggaccctt 550

 gggcctgcat ctgactccca gctgcagagt cagaagctga gtccaggcaa 600

 ctgcttggcc actcccgatc gctcctccct ggacacccgg ttaccaaagt 650

 cagcaaagaa gatgcggtaa tcgccgcctg atctccacat ggtgaacaca 700

 acactcccac caacacctcc ttgactggtc ggtcttcagc accgggggtg 750

 ggcaggcagg tgttctgtgt tgacgagaat tgcacaggct aaacacaaac 800

 acggaaccag agtgagaaca cctcactcac ggcagcccag gctgctccct 850

 accaggtgac ggagcgcgcc ggggctgtgg gtgccagggg ctgagtgcta 900

 gggactcgtc atgagtgggg atccccacgt tcctgtcact gctgtcaaac 950

 agaaggtaaa cagtcatatg aatgtatttc cttaggaaaa cttgtaaaaa 1000

 cttttattag gatatctatt taatactgaa ctttggccta ctttgtgata 1050

 gactataaac aaattgagga aatcactatt tctcacttct gtattttctc 1100

 aaaaataatt ttgttacaga gttcaatata ctgtgtacca ttgatcttct 1150

 attgtgaaag caaagaattt catcaaaata ttttaaatta tgagtgaaaa 1200

 ttgtgtatgt taattttgca gctataatat taatcaaatt ttgtgtaatt 1250

 ctaatcacaa aatgacgtgc cttaagtgcc cctccagctg tgggttggca 1300

 gtgtccagac agggagggcc catcaccgaa atcctgaacg attactagac 1350

 caattctatt aaaaacattt caaggcaaaa aaaaaaaaaa aaa 1393

<210> 4190
<211> 133
<212> PRT
<213> Homo sapien

<400> 4190
 Glu Ser Leu Val Gly Lys Val His Asn Phe Pro Leu Ile Ala Phe
   1               5                  10                  15

 Tyr Cys Cys Glu Lys Gly Lys Arg Gln Pro His Lys Ser Leu His
                  20                  25                  30

 Asp Arg Cys Phe Gly Glu Ala Leu Asp Pro Asn Cys Ser His Cys
                  35                  40                  45

 Tyr Leu Asp Gln Ile Lys Arg Ser Asp Phe Leu Gly Phe Ser Gly
                  50                  55                  60

 Tyr Ser Pro His Phe Val Ala Thr Ser Thr Asn Ser Glu His Lys
                  65                  70                  75

 Met Gln Pro Ser Ser Met Gln Gln Ala Leu Pro Ser Gln Trp Pro
                  80                  85                  90

 Tyr Trp Thr Asp Pro Arg Pro Ala Leu Val Pro Cys Cys Ser His
                  95                 100                 105

 Arg Pro Asp Val His Arg Ser Arg Pro Gly Pro Gly Leu Pro Gly
                 110                 115                 120

 Thr Ser Gly Cys Ser Asp Arg Pro Pro Val Cys Pro Ile
                 125                 130

<210> 4191
<211> 1610
<212> DNA
<213> Homo sapien

<400> 4191
 atttttgaaa attaattggg aaggtactgg ttttaagtgt agttgccgac 50

 gcaatggcag cctttgcagt ggaacctcag gggcccgcgt taggatctga 100

 accaatgatg ctgggttcac ccacatctcc aaagccagga gttaatgccc 150

 agttcttacc tggattttta atgggggatt tgccagctcc ggtgactcca 200

 caacctcgat caattagtgg cccttcagta ggagtaatgg aaatgagatc 250

 acctttactt gcaggtgggt caccaccaca accagttgta ccagctcata 300

 aagataaaag tggcgctcca ccagttagaa gtatatatga tgacatttct 350

 agcccaggac ttggatcaac acctttaact tcaagaagac agccaaacat 400

 ttcagtaatg cagagtcctc ttgttggagt tacatctact cctggaacag 450

 ggcaaagtat gtttagtcca gcaagtatcg gtcagccacg aaagacgaca 500

 ttatctcctg cccagttgga tcctttttat actcaaggag attctttgac 550

 ttcagaagat cacctcgatg actcttgggt gactgtattt gggtttcctc 600

 aagcatctgc ttcctacata ttactacaat ttgcacagta tgggaatatc 650

 ttaaaacatg tgatgtctaa tacaggaaat tggatgcata ttcgttatca 700

 atctaaactg caggctcgga aagccttaag caaagatggg aggatttttg 750

 gagaatccat catgattggt gtaaaaccat gtattgacaa aagtgttatg 800

 gaaagcagtg acagatgtgc tttatcatct ccatctttag cctttacacc 850

 accaatcaaa actctaggta caccaacaca acctggaagt actcctagga 900

 tttctaccat gagacctctt gctacagcat acaaagcctc tactagtgat 950

 tatcaggtta tttctgacag acaaacgcca aaaaaaagat gaaagtcttg 1000

 tatccaaagc aatggagtac atgtttggct ggtagtagaa caccaagaag 1050

 gaggttgcta cactaaaaca gagttagcag agtgctgctg gttccttcgg 1100

 ttagttatat aactgttcct gcagtattgg atagctatct catacttctt 1150

 ttagaaagaa gcctttttca ttaaggatac aacctatttg tagctcgcac 1200

 tttaaaagat gcttgagata cattttaaag aaaactaaaa atccctgtaa 1250

 ataggatttt gtgctttctg taacagtgca tgcttcagca cagaaaactc 1300

 agcattgatt attgtaaatt aaataactga aattgtggtg agacgtcata 1350

 gtcttcatga gaacgtgggg gtgaatttca tgaaggggaa ctatagttat 1400

 ttctaccgac acaaatatta taattagcaa tttgaattat ggtcttttaa 1450

 tttagatagt atttaatatt ttaattatcc ttgtttgtat atgtcctgtc 1500

 acagagtgtc ctcttggtgt attctaaaac gagcattctt ttaaaaaacc 1550

 taaagtttct tgataataaa cattgtcaat gataaaaaaa aaaaaaaaaa 1600

 aaaaaaaaaa 1610

<210> 4192
<211> 329
<212> PRT
<213> Homo sapien

<400> 4192
 Ile Phe Lys Leu Ile Gly Lys Val Leu Val Leu Ser Val Val Ala
   1               5                  10                  15

 Asp Ala Met Ala Ala Phe Ala Val Glu Pro Gln Gly Pro Ala Leu
                  20                  25                  30

 Gly Ser Glu Pro Met Met Leu Gly Ser Pro Thr Ser Pro Lys Pro
                  35                  40                  45

 Gly Val Asn Ala Gln Phe Leu Pro Gly Phe Leu Met Gly Asp Leu
                  50                  55                  60

 Pro Ala Pro Val Thr Pro Gln Pro Arg Ser Ile Ser Gly Pro Ser
                  65                  70                  75

 Val Gly Val Met Glu Met Arg Ser Pro Leu Leu Ala Gly Gly Ser
                  80                  85                  90

 Pro Pro Gln Pro Val Val Pro Ala His Lys Asp Lys Ser Gly Ala
                  95                 100                 105

 Pro Pro Val Arg Ser Ile Tyr Asp Asp Ile Ser Ser Pro Gly Leu
                 110                 115                 120

 Gly Ser Thr Pro Leu Thr Ser Arg Arg Gln Pro Asn Ile Ser Val
                 125                 130                 135

 Met Gln Ser Pro Leu Val Gly Val Thr Ser Thr Pro Gly Thr Gly
                 140                 145                 150

 Gln Ser Met Phe Ser Pro Ala Ser Ile Gly Gln Pro Arg Lys Thr
                 155                 160                 165

 Thr Leu Ser Pro Ala Gln Leu Asp Pro Phe Tyr Thr Gln Gly Asp
                 170                 175                 180

 Ser Leu Thr Ser Glu Asp His Leu Asp Asp Ser Trp Val Thr Val
                 185                 190                 195

 Phe Gly Phe Pro Gln Ala Ser Ala Ser Tyr Ile Leu Leu Gln Phe
                 200                 205                 210

 Ala Gln Tyr Gly Asn Ile Leu Lys His Val Met Ser Asn Thr Gly
                 215                 220                 225

 Asn Trp Met His Ile Arg Tyr Gln Ser Lys Leu Gln Ala Arg Lys
                 230                 235                 240

 Ala Leu Ser Lys Asp Gly Arg Ile Phe Gly Glu Ser Ile Met Ile
                 245                 250                 255

 Gly Val Lys Pro Cys Ile Asp Lys Ser Val Met Glu Ser Ser Asp
                 260                 265                 270

 Arg Cys Ala Leu Ser Ser Pro Ser Leu Ala Phe Thr Pro Pro Ile
                 275                 280                 285

 Lys Thr Leu Gly Thr Pro Thr Gln Pro Gly Ser Thr Pro Arg Ile
                 290                 295                 300

 Ser Thr Met Arg Pro Leu Ala Thr Ala Tyr Lys Ala Ser Thr Ser
                 305                 310                 315

 Asp Tyr Gln Val Ile Ser Asp Arg Gln Thr Pro Lys Lys Arg
                 320                 325

<210> 4193
<211> 5954
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3543-3566, 5007-5030
<223> Unknown base

<400> 4193
 cggccgccgg ccgccgagcg cgggagggca ggcaggggca ggagccggag 50

 ggcccggggc gcggcgcggc atgtagctgc gggctcccgc gtcgcgtgag 100

 gctgtcggcc cggggccccg ccatggctgg gatggacagt ggcaacctga 150

 agaccgcgag gctgtggcgg gacgccgccc tgcgtgccag gaagctgcgg 200

 agcaacctgc gccagctcac gcttaccgcc gccggggcct gccccggggc 250

 cggggccgac gcgctcgagt cccccgcctc cccccagctc gtgctgccgg 300

 ccaacctcgg ggacattgag gcactgaacc tggggaacaa cggcctggag 350

 gaggtacccg aggggctggg gtcggcgctg ggcagcctgc gcgtcctggt 400

 cctgcgcagg aaccgcttcg cccggctgcc cccggcggtg gccgagctcg 450

 gccaccacct caccgagctg gacgtgagcc acaaccggct gaccgccctg 500

 ggcgcggagg tggtgagtgc tctgagggag ctgcggaagc tcaacctcag 550

 ccacaaccag ctgcccgccc tgcccgccca gctgggcgct ctcgctcacc 600

 tggaggagct ggatgtcagc tttaaccggc tggcgcacct gcctgactcc 650

 ctctcctgcc tctcccgcct gcgcaccctg gacgtggatc acaaccagct 700

 cactgccttc ccccggcagc tgctgcagct ggtggccctg gaggagctgg 750

 acgtgtccag caaccggctg cggggcctgc ctgaggatat cagtgccctg 800

 cgtgccctca agatcctctg gctgagtggg gccgagcttg gcacgctgcc 850

 cgccggcttc tgcgagctgg ccagtttgga gagcctcatg ctagacaaca 900

 acgggctgca ggctctgccc gcccagttca gctgcctgca gcggctcaaa 950

 atgctcaacc tgtcctccaa cctcttcgag gagttccctg ccgcgctgct 1000

 gcccttggct ggtctggagg agctctacct tagtcgcaac cagctcacct 1050

 cggtgccatc cgcttatctc gggcctgggc cggctttctc accttgtggc 1100

 tggataataa ccgcatccgc tacctgccgg actccatcgt ggagctgacc 1150

 ggcctggagg agctcgtgct gcaggggaac cagatcgcgg tgctgcccga 1200

 ccactttggc cagctctccc gggtgggttt gtggaagatc aaagacaacc 1250

 cactgatcca gcccccctac gaggtctgca tgaaggggat cccctacatc 1300

 gcagcctacc agaaggaact ggctcattcc cagccggcgg tgcagccccg 1350

 gctcaagctg ctcctgatgg ggcataaggc tgcaggaaag actttgctgc 1400

 gccactgcct caccgaggag agagtggagg gatgcccagg aggaggggac 1450

 aaggagaagt gctacccacc gtcacctccc cctgtgagca agggcatcga 1500

 ggtgaccagc tggacggccg atgcctcccg gggcctgcgg ttcatcgtgt 1550

 atgacttagc tggggatgaa agttatgagg tgatccagcc cttcttcctg 1600

 tccccagggg ccctatacgt gctggtggtc aacttggcca cctatgagcc 1650

 tcgccacttt cctaccaccg tgggctcctt cttgcatcgg gtcggggcga 1700

 gagtgcccca cgcggtggtg tgcatcgtgg gcacccacgc agacctgtgc 1750

 ggagagcgtg agctggagga gaaatgtctg gacattcacc gccagatcgc 1800

 cctgcaggag aagcacgacg cggagggact gagccgcttg gccaaggtgg 1850

 tggacgaggc actggcccgg gacttcgagc tgcgctctgc cagcccccac 1900

 gcagcctact atggcgtttc ggacaagaac cttcgacggc gcaaggccca 1950

 ttttcaatac ctgctcaacc accggctgca gatcctctcc cccgtgttgc 2000

 ctgttagctg cagggacccg cgccacttac gacgccttcg ggacaagttg 2050

 ctgtcagttg ctgagcaccg agagatcttc cccaacttac acagagtact 2100

 gcctcgatcc tggcaggtgc tggaggaact gcatttccag ccacctcagg 2150

 cccagcgact gtggctaagc tggtgggact cggcgcgctt gggcctgcag 2200

 gcgggtctga ccgaggaccg actgcagagt gccctctcct acctgcatga 2250

 gagcggcaag ctactctact ttgaggacag tccggctctc aaggagcacg 2300

 tcttccacaa cctcacccgc ctcatcgaca tcctcaatgt cttcttccag 2350

 agggatccct ctttgctgct gcataagctg ctcctaggga ccagtggaga 2400

 gggcaaggcg gagggggaaa gctccccgcc catggcgcgg tccaccccca 2450

 gccaggaact gctccgggcc acccagctcc atcagtatgt ggagggcttt 2500

 ctgttgcatg ggctcttgcc agctcatgtc attcggttgc tgcttaagcc 2550

 tcatgtccag gcccagcagg acttgcagct gttgctggag ctgctggaga 2600

 agatgggact ctgttactgc ctcaataaac ccaagggcaa gcctttgaat 2650

 gggtccacag cttggtacaa gttcccatgc tatgtgcaga acgaggtgcc 2700

 ccatgcagaa gcctggatta atgggaccaa cctagctggg cagtcttttg 2750

 tggctgagca gttgcagatt gaatatagct ttccttttac ttttccacct 2800

 gggttgtttg cacgctacag tgtccagatc aacagccatg tggtgcacag 2850

 gtcggatggt aaatttcaga tctttgccta tagagggaaa gttcctgtgg 2900

 ttgtgagtta cagacctgcc aggggagtcc tgcagccaga caccctgtcc 2950

 attgctagcc atgcatcatt accaaatata tggaccgcat ggcaagccat 3000

 aacccccttg gtggaggaac tgaatgtcct acttcaggaa tggcctggac 3050

 tgcactacac cgtgcacatt ctctgttcta agtgccttaa gagaggatcg 3100

 cccaatccac atgcttttcc aggggagttg ctgagtcagc ccagaccgga 3150

 aggagtggca gagatcattt gccccaagaa cggcagcgag cgagtaaatg 3200

 ttgccttggt ttacccaccc acgccaactg tgatcagccc ctgttccaag 3250

 aagaatgttg gtgaaaagca cagaaaccag tgacgtttgt ggctgtggaa 3300

 tttccatgga gaaaagagag catctgaaca cctggaccat cttttgcacc 3350

 tggcagaccc tctgcactca ccccagcgtg ttctgtgaac ttgagtgaca 3400

 acgcgtgctt gcagggtgct ttttggatga ctggggaaga ggtggggagg 3450

 gggtggtggg gggaagcatg gacgagaaca tggagcaaat gttttacaac 3500

 ctgaacctca gaactgtgat cctccaagga gcgcgctact tgnnnnnnnn 3550

 nnnnnnnnnn nnnnnngtcg aatggcttct cagggatttt gttttccgtg 3600

 cacatataag ccatagttac agtacaggtg gcagtattta gagcactcag 3650

 atttcagttc tgttaaatgt gaaagaggga tcgactgacg ttcattgctg 3700

 ttccataact agtgtaaaat atgtatatgt ttatctttat ttttataata 3750

 tgcaaataca tttaaattta tacagtttga agcttctagc gttagttcac 3800

 actgggtgca atattctgca tgagaactgt gccaagatgg ggctgatttc 3850

 ttattttagt ataagacttt tttgtttttt ctttattctt taatcctctt 3900

 cacattaaaa aaaaaaaatc tctctgttag cccatggatt aagtgttggt 3950

 tcatagagat tgccaataat cagaaagaac cttaaatgtg catttaagac 4000

 agtgtccctt cccttctttt caatgaaggt ccctgcctat ataaatcatc 4050

 tggcacgctg gtgggaaatc ctttgctctt ccaacgtgtt attagtgctg 4100

 ggcagagatg gggcacactc aggggccaaa gaggacaaaa agtccatgca 4150

 aaacttgagt cttttaatgg cttaagataa tcaggagtca gttctgaatc 4200

 ttacaaagtg ctctgcttaa taagtacctt acttagcaga gcactttgca 4250

 aacatattac ttattagcag agctctttgt agaccttcca catctggctg 4300

 tcagatctta aggttgtgaa tttaggctcc agttacattc actggagagc 4350

 ataatcccac acgggttatt tataaataca gagcctctga ttggacggtc 4400

 tcctgccaag aactagtaat acccttgttt taaaatcttc acaaggtaaa 4450

 acttaaaaag ccaaccaaac aaattgctct ccattctact tttaattggg 4500

 ccaaacagca tatgctacag tagtaacatg tttttcggag agtgtaaaaa 4550

 actctgttta catttgcctc ctccgtgggt tgatcgaaaa tgtataaaac 4600

 tgactgcttc tcgccagcct cagacaagaa gagtgagttg ctggtactcg 4650

 ctactctttt acttcttttg taaagtattg actcttggaa ggctacagta 4700

 tacaaagtct caacatgttt tttaaaagaa ataaggagca agcgactgcc 4750

 ctgctagaaa tcacaaaccg atttttgtag aatattttgt gccccaggca 4800

 ttaatttcac tgactccaga acctgcagtt cagagaatga tttcttatga 4850

 tgataaaaat cgaatgggat cagacgatgt ttgcattttt ttaatacttg 4900

 aataggacac ctcaagtttg agatttcatt ttcttttaga acacagtcac 4950

 aagattaatc tggtgaatcc ttttgtcaca gttctcgtgt gtgtgtgcgc 5000

 gtctccnnnn nnnnnnnnnn nnnnnnnnnn aaaactgaat ggtcacattt 5050

 aattgctttt tggaccattg aatagttggg aagtaagaat tttttaattg 5100

 gcatgagacg gttcctcaac tgttaaatta accaactttg acctgtcttt 5150

 agaaaaaggc ttatttgtat gattttgggc taactccccg gggaccatat 5200

 taaatgacaa aaatgctcct ttgggtgaca caccctacaa agtatttgct 5250

 gttacgaaca taaacgccca cattcttaat atctaatatt tttgaccagt 5300

 gatgttttat gctgtcatct gaaccctaga gaagcagtgt cagaggaaac 5350

 cttggtgtca catgtgtctt agcaaaaggg ttaccatgat cgagggtcat 5400

 gtgaccaaaa gatgctccag agaagcttga gaatttgttt caagttggga 5450

 ggagggttgg agatacaaaa atcactctgc tctacaggac tcttcagctg 5500

 tctatgcaag aaattccgtt ttctctttca gcacctggaa agacacagca 5550

 gcccaccgag gcgataggtg attcactaag cacaagagga atgttttcta 5600

 agcaaggcgt cccttgcctc tcaaacaaat gccctccaag tttgttaggg 5650

 tttctattcc tgcaacttgt agtatcaaaa ccacttcctg gaattgtcaa 5700

 agcactgcca aaataaatgt ttttccccct tctaagaaaa aaaaaatgac 5750

 agtgctcata tttgacactt gtgtattgga ctctcttttg aatgaataaa 5800

 aaggaaaagg ggtttggtgt aattcctgat ggggtgcgtg ttgtttttca 5850

 tgccatggtt tgtgaatttt aattgtggtt tcccatttcg ttgttgtaac 5900

 tgggcagaaa ttaaaaaaga aaaatcaata aaaatacaaa gaaatggtta 5950

 aaaa 5954

<210> 4194
<211> 1093
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3543-3566, 5007-5030
<223> Unknown amino acid

<400> 4194
 Ala Ala Gly Arg Arg Ala Arg Glu Gly Arg Gln Gly Gln Glu Pro
   1               5                  10                  15

 Glu Gly Pro Gly Arg Gly Ala Ala Cys Ser Cys Gly Leu Pro Arg
                  20                  25                  30

 Arg Val Arg Leu Ser Ala Arg Gly Pro Ala Met Ala Gly Met Asp
                  35                  40                  45

 Ser Gly Asn Leu Lys Thr Ala Arg Leu Trp Arg Asp Ala Ala Leu
                  50                  55                  60

 Arg Ala Arg Lys Leu Arg Ser Asn Leu Arg Gln Leu Thr Leu Thr
                  65                  70                  75

 Ala Ala Gly Ala Cys Pro Gly Ala Gly Ala Asp Ala Leu Glu Ser
                  80                  85                  90

 Pro Ala Ser Pro Gln Leu Val Leu Pro Ala Asn Leu Gly Asp Ile
                  95                 100                 105

 Glu Ala Leu Asn Leu Gly Asn Asn Gly Leu Glu Glu Val Pro Glu
                 110                 115                 120

 Gly Leu Gly Ser Ala Leu Gly Ser Leu Arg Val Leu Val Leu Arg
                 125                 130                 135

 Arg Asn Arg Phe Ala Arg Leu Pro Pro Ala Val Ala Glu Leu Gly
                 140                 145                 150

 His His Leu Thr Glu Leu Asp Val Ser His Asn Arg Leu Thr Ala
                 155                 160                 165

 Leu Gly Ala Glu Val Val Ser Ala Leu Arg Glu Leu Arg Lys Leu
                 170                 175                 180

 Asn Leu Ser His Asn Gln Leu Pro Ala Leu Pro Ala Gln Leu Gly
                 185                 190                 195

 Ala Leu Ala His Leu Glu Glu Leu Asp Val Ser Phe Asn Arg Leu
                 200                 205                 210

 Ala His Leu Pro Asp Ser Leu Ser Cys Leu Ser Arg Leu Arg Thr
                 215                 220                 225

 Leu Asp Val Asp His Asn Gln Leu Thr Ala Phe Pro Arg Gln Leu
                 230                 235                 240

 Leu Gln Leu Val Ala Leu Glu Glu Leu Asp Val Ser Ser Asn Arg
                 245                 250                 255

 Leu Arg Gly Leu Pro Glu Asp Ile Ser Ala Leu Arg Ala Leu Lys
                 260                 265                 270

 Ile Leu Trp Leu Ser Gly Ala Glu Leu Gly Thr Leu Pro Ala Gly
                 275                 280                 285

 Phe Cys Glu Leu Ala Ser Leu Glu Ser Leu Met Leu Asp Asn Asn
                 290                 295                 300

 Gly Leu Gln Ala Leu Pro Ala Gln Phe Ser Cys Leu Gln Arg Leu
                 305                 310                 315

 Lys Met Leu Asn Leu Ser Ser Asn Leu Phe Glu Glu Phe Pro Ala
                 320                 325                 330

 Ala Leu Leu Pro Leu Ala Gly Leu Glu Glu Leu Tyr Leu Ser Ser
                 335                 340                 345

 Gln Pro Ala His Leu Gly Ala Ile Arg Leu Ser Arg Ala Trp Ala
                 350                 355                 360

 Gly Phe Leu Thr Leu Trp Leu Asp Asn Asn Arg Ile Arg Tyr Leu
                 365                 370                 375

 Pro Asp Ser Ile Val Glu Leu Thr Gly Leu Glu Glu Leu Val Leu
                 380                 385                 390

 Gln Gly Asn Gln Ile Ala Val Leu Pro Asp His Phe Gly Gln Leu
                 395                 400                 405

 Ser Arg Val Gly Leu Trp Lys Ile Lys Asp Asn Pro Leu Ile Gln
                 410                 415                 420

 Pro Pro Tyr Glu Val Cys Met Lys Gly Ile Pro Tyr Ile Ala Ala
                 425                 430                 435

 Tyr Gln Lys Glu Leu Ala His Ser Gln Pro Ala Val Gln Pro Arg
                 440                 445                 450

 Leu Lys Leu Leu Leu Met Gly His Lys Ala Ala Gly Lys Thr Leu
                 455                 460                 465

 Leu Arg His Cys Leu Thr Glu Glu Arg Val Glu Gly Cys Pro Gly
                 470                 475                 480

 Gly Gly Asp Lys Glu Lys Cys Tyr Pro Pro Ser Pro Pro Pro Val
                 485                 490                 495

 Ser Lys Gly Ile Glu Val Thr Ser Trp Thr Ala Asp Ala Ser Arg
                 500                 505                 510

 Gly Leu Arg Phe Ile Val Tyr Asp Leu Ala Gly Asp Glu Ser Tyr
                 515                 520                 525

 Glu Val Ile Gln Pro Phe Phe Leu Ser Pro Gly Ala Leu Tyr Val
                 530                 535                 540

 Leu Val Val Asn Leu Ala Thr Tyr Glu Pro Arg His Phe Pro Thr
                 545                 550                 555

 Thr Val Gly Ser Phe Leu His Arg Val Gly Ala Arg Val Pro His
                 560                 565                 570

 Ala Val Val Cys Ile Val Gly Thr His Ala Asp Leu Cys Gly Glu
                 575                 580                 585

 Arg Glu Leu Glu Glu Lys Cys Leu Asp Ile His Arg Gln Ile Ala
                 590                 595                 600

 Leu Gln Glu Lys His Asp Ala Glu Gly Leu Ser Arg Leu Ala Lys
                 605                 610                 615

 Val Val Asp Glu Ala Leu Ala Arg Asp Phe Glu Leu Arg Ser Ala
                 620                 625                 630

 Ser Pro His Ala Ala Tyr Tyr Gly Val Ser Asp Lys Asn Leu Arg
                 635                 640                 645

 Arg Arg Lys Ala His Phe Gln Tyr Leu Leu Asn His Arg Leu Gln
                 650                 655                 660

 Ile Leu Ser Pro Val Leu Pro Val Ser Cys Arg Asp Pro Arg His
                 665                 670                 675

 Leu Arg Arg Leu Arg Asp Lys Leu Leu Ser Val Ala Glu His Arg
                 680                 685                 690

 Glu Ile Phe Pro Asn Leu His Arg Val Leu Pro Arg Ser Trp Gln
                 695                 700                 705

 Val Leu Glu Glu Leu His Phe Gln Pro Pro Gln Ala Gln Arg Leu
                 710                 715                 720

 Trp Leu Ser Trp Trp Asp Ser Ala Arg Leu Gly Leu Gln Ala Gly
                 725                 730                 735

 Leu Thr Glu Asp Arg Leu Gln Ser Ala Leu Ser Tyr Leu His Glu
                 740                 745                 750

 Ser Gly Lys Leu Leu Tyr Phe Glu Asp Ser Pro Ala Leu Lys Glu
                 755                 760                 765

 His Val Phe His Asn Leu Thr Arg Leu Ile Asp Ile Leu Asn Val
                 770                 775                 780

 Phe Phe Gln Arg Asp Pro Ser Leu Leu Leu His Lys Leu Leu Leu
                 785                 790                 795

 Gly Thr Ser Gly Glu Gly Lys Ala Glu Gly Glu Ser Ser Pro Pro
                 800                 805                 810

 Met Ala Arg Ser Thr Pro Ser Gln Glu Leu Leu Arg Ala Thr Gln
                 815                 820                 825

 Leu His Gln Tyr Val Glu Gly Phe Leu Leu His Gly Leu Leu Pro
                 830                 835                 840

 Ala His Val Ile Arg Leu Leu Leu Lys Pro His Val Gln Ala Gln
                 845                 850                 855

 Gln Asp Leu Gln Leu Leu Leu Glu Leu Leu Glu Lys Met Gly Leu
                 860                 865                 870

 Cys Tyr Cys Leu Asn Lys Pro Lys Gly Lys Pro Leu Asn Gly Ser
                 875                 880                 885

 Thr Ala Trp Tyr Lys Phe Pro Cys Tyr Val Gln Asn Glu Val Pro
                 890                 895                 900

 His Ala Glu Ala Trp Ile Asn Gly Thr Asn Leu Ala Gly Gln Ser
                 905                 910                 915

 Phe Val Ala Glu Gln Leu Gln Ile Glu Tyr Ser Phe Pro Phe Thr
                 920                 925                 930

 Phe Pro Pro Gly Leu Phe Ala Arg Tyr Ser Val Gln Ile Asn Ser
                 935                 940                 945

 His Val Val His Arg Ser Asp Gly Lys Phe Gln Ile Phe Ala Tyr
                 950                 955                 960

 Arg Gly Lys Val Pro Val Val Val Ser Tyr Arg Pro Ala Arg Gly
                 965                 970                 975

 Val Leu Gln Pro Asp Thr Leu Ser Ile Ala Ser His Ala Ser Leu
                 980                 985                 990

 Pro Asn Ile Trp Thr Ala Trp Gln Ala Ile Thr Pro Leu Val Glu
                 995                1000                1005

 Glu Leu Asn Val Leu Leu Gln Glu Trp Pro Gly Leu His Tyr Thr
                1010                1015                1020

 Val His Ile Leu Cys Ser Lys Cys Leu Lys Arg Gly Ser Pro Asn
                1025                1030                1035

 Pro His Ala Phe Pro Gly Glu Leu Leu Ser Gln Pro Arg Pro Glu
                1040                1045                1050

 Gly Val Ala Glu Ile Ile Cys Pro Lys Asn Gly Ser Glu Arg Val
                1055                1060                1065

 Asn Val Ala Leu Val Tyr Pro Pro Thr Pro Thr Val Ile Ser Pro
                1070                1075                1080

 Cys Ser Lys Lys Asn Val Gly Glu Lys His Arg Asn Gln
                1085                1090

<210> 4195
<211> 4215
<212> DNA
<213> Homo sapien

<400> 4195
 gggcgacacc cgggccgtgc cgccagcgtc cgtcgggaga gtgaaggctc 50

 gcaacgcctt gcccggggga aggtaacgcg ccgcgcccgg ggctgcgcgg 100

 tttgcaccgc caggccgagg gctgggggcc agaagacaag agagacggcg 150

 aggcgcgctc cctgcccggc agcgactcgg aggtaggtga tgctctgatg 200

 ctgctgcctc ttatgaattg acgacaggtg cagagagaga ataaactgtg 250

 tctaagactg gaccagagag tgagtgtgct ggaagccacc ataggaacaa 300

 gcgacctgtt tggcaaggaa tacagcatcc ttctgagagc ctcttctcga 350

 cactatccca cagaccagga cttcctcatg ggaaagagca cttaggatct 400

 tgctatcagc tgccctaaac ttttgctgag ccaaaataag actttgatgc 450

 agaactgaac aagatatttc atttttgtgt gttttaatct tcctggttgc 500

 agtcttagtt gttcagccct gagaattttg agccacattt gttgctatta 550

 tttttgcatg cacttttcaa aatgattgac ttaagcttcc tgactgaaga 600

 ggaacaagag gccatcatga aggttttgca gcgggatgct gctctgaaga 650

 gggccgaaga agagagagtc agacatttgc ctgaaaaaat taaggatgac 700

 cagcagctga agaatatgag tggccaatgg ttttatgaag ccaaggcaaa 750

 aaggcacagg gacaaaatcc atggcgcaga tatcatcaga gcatctatga 800

 gaaagaagag gccccagata gcagctgagc agagtaaaga cagagaaaat 850

 ggggcaaagg aaagctgggt gaataatgtc aacaaagatg ctttccttcc 900

 tccagagctg gctggcgttg tagaagagcc agaagaagat gcagcaccag 950

 caagcccgag ttccagtgtg gtaaatccag cttccagtgt gattgatatg 1000

 tcccaggaaa acacaaggaa accaaatgtg tctccagaga agaggaagaa 1050

 tccgtttaat agctccaagt tgccagaagg tcactcatca caacaaacta 1100

 aaaatgaaca gtcaaaaaat ggaagaactg gtttatttca gacttcaaaa 1150

 gaggatgaat tgtcagagtc aaaagaaaag tcaactgtcg cagatacttc 1200

 aatccaaaag ttagagaaat caaagcagac tttgccaggc ctttcaaatg 1250

 ggtcccaaat caaggctcca atccccaaag ccaggaagat gatctacaaa 1300

 tcaactgatt taaacaaaga tgataaccag tcttttccta gacaaaggac 1350

 agactccctg aaagcgagag gggctccgag agggatcctc aagcgcaact 1400

 ccagttccag tagcacagac tcagaaaccc ttcgttataa tcacaacttt 1450

 gaacccaaaa gcaaaattgt gtcacctggc ctaaccatcc atgagagaat 1500

 ttctgagaag gagcattctt tagaagacaa ctcttcccca aactccctgg 1550

 agccattaaa gcatgtgaga ttctctgcag tgaaggatga gcttccacag 1600

 agtcctgggc taatccatgg tcgggaagta ggagaattta gtgttttaga 1650

 atctgacaga ttgaaaaatg gaatggaaga tgcaggggac acagaagagt 1700

 ttcagagtga ccctaagcct tctcaataca gaaagccttc gctttttcat 1750

 caatcaacct caagcccata tgtatcaaaa agtgaaacac atcagccaat 1800

 gacttctggt tcttttccaa ttaatgggct gcattctcat tcagaagttt 1850

 taactgcaag accacagtct atggagaatt caccaaccat caatgaaccc 1900

 aaagataaat catcagaatt aacaaggctt gaatctgtat tacccagaag 1950

 ccctgctgat gaactgtctc attgtgttga gcctgagcca tctcaggtgc 2000

 caggtggcag ttctagagac cgtcagcaag gttcagaaga agaacccagt 2050

 cctgttttga aaactttgga aaggagtgcc gctaggaaaa tgccttccaa 2100

 aagtctagaa gacatttcat cagattcatc aaatcaagca aaagtagata 2150

 atcagccaga agaattagtg cgtagtgctg aagatgatga gaaaccagat 2200

 cagaagccag ttacaaatga atgcgtacca agaatttcca cagtgcctac 2250

 acaacctgat aatccatttt ctcaccctga caaactcaaa aggatgagca 2300

 agtctgttcc agcatttctc caagatgagg tgagtggcag tgtgatgagt 2350

 gtttatagtg gagactttgg caatctggaa gttaaaggaa atattcagtt 2400

 tgcaattgaa tatgtggagt cactgaagga gttgcatgtt tttgtggccc 2450

 agtgtaagga cttagcagca gcggatgtaa aaaaacagcg ttcagaccca 2500

 tatgtaaagg cctatttgct accagacaaa ggcaaaatgg gcaagaagaa 2550

 aacactcgta gtgaagaaaa ccttgaatcc tgtgtataac gaaatactgc 2600

 ggtataaaat tgaaaaacaa atcttaaaga cacagaaatt gaacctgtcc 2650

 atttggcatc gggatacatt taagcgcaat agtttcctag gggaggtgga 2700

 acttgatttg gaaacatggg actgggataa caaacagaat aaacaattga 2750

 gatggtaccc tctgaagcgg aagacagcac cagttgccct tgaagcagaa 2800

 aacagaggtg aaatgaaact agctctccag tatgtcccag agccagtccc 2850

 tggtaaaaag cttcctacaa ctggagaagt gcacatctgg gtgaaggaat 2900

 gccttgatct accactgcta aggggaagtc atctaaattc ttttgttaaa 2950

 tgtaccatcc ttccagatac aagtaggaaa agtcgccaga agacaagagc 3000

 tgtagggaaa accaccaacc ctatcttcaa ccacactatg gtgtatgatg 3050

 ggttcaggcc tgaagatctg atggaagcct gtgtagagct tactgtctgg 3100

 gaccattaca aattaaccaa ccaatttttg ggaggtcttc gtattggctt 3150

 tggaacaggt aaaagttatg ggactgaagt ggactggatg gactctactt 3200

 cagaggaagt tgctctctgg gagaagatgg taaactcccc caatacttgg 3250

 attgaagcaa cactgcctct cagaatgctt ttgattgcca agatttccaa 3300

 atgagcccaa attccactgg ctcctccact gaaaactact aaaccggtgg 3350

 aatctgatct tgaaaatctg agtaggtgga caaatatcct cactttctat 3400

 ctattgcacc taaggaatac tacacagcat gtaaaagtca atctgcatgt 3450

 gcttctttga ttacaaggcc caagggattt aaatataaca aaatgtgtaa 3500

 tttgtgactc taatattaaa taagatattt gaacaagcta ggaaaattga 3550

 atttctgctg ctgcttcaaa gaaaaagctg ccccagagca ttaaacatgg 3600

 ggtattgtta agaagcaaaa tgttcttgtt tgccatcatg tgtttcacac 3650

 cacaattctg tgccacagtt aagagggtct ggtacccttg caggaccttt 3700

 gtaggttgtg ggaaaaagtc gcagaaagat actcaaagtg gagcagggaa 3750

 tggagacaga catcagtgat gataaaaaaa aaaatggacc ttaagaaact 3800

 atttactctg taatctctaa taaaatatgg aattccatat tagggcaatg 3850

 agactgaaac tactggtgtt tttctgcctt gagaaaacaa acagttaaaa 3900

 caagcctcaa atgtatttta gtgccaccca ctggccatag gtacaattca 3950

 gttgttggct tgttttgact taattctaaa ataggtctca agcctgtatt 4000

 tttatgagtt tattttttta aaaccctgca tatatatgat tgtttttctt 4050

 ataactttac tatatgaaag cagcataaga gtagtcacaa acatgttttg 4100

 caacaaagtt ttaattagaa tgtaagttgc tcagttatac tgttcttctt 4150

 atgtatgtaa aattttcgta ttttgtaaaa acccttagaa taaattatca 4200

 tttgatttaa attgt 4215

<210> 4196
<211> 910
<212> PRT
<213> Homo sapien

<400> 4196
 Met Ile Asp Leu Ser Phe Leu Thr Glu Glu Glu Gln Glu Ala Ile
   1               5                  10                  15

 Met Lys Val Leu Gln Arg Asp Ala Ala Leu Lys Arg Ala Glu Glu
                  20                  25                  30

 Glu Arg Val Arg His Leu Pro Glu Lys Ile Lys Asp Asp Gln Gln
                  35                  40                  45

 Leu Lys Asn Met Ser Gly Gln Trp Phe Tyr Glu Ala Lys Ala Lys
                  50                  55                  60

 Arg His Arg Asp Lys Ile His Gly Ala Asp Ile Ile Arg Ala Ser
                  65                  70                  75

 Met Arg Lys Lys Arg Pro Gln Ile Ala Ala Glu Gln Ser Lys Asp
                  80                  85                  90

 Arg Glu Asn Gly Ala Lys Glu Ser Trp Val Asn Asn Val Asn Lys
                  95                 100                 105

 Asp Ala Phe Leu Pro Pro Glu Leu Ala Gly Val Val Glu Glu Pro
                 110                 115                 120

 Glu Glu Asp Ala Ala Pro Ala Ser Pro Ser Ser Ser Val Val Asn
                 125                 130                 135

 Pro Ala Ser Ser Val Ile Asp Met Ser Gln Glu Asn Thr Arg Lys
                 140                 145                 150

 Pro Asn Val Ser Pro Glu Lys Arg Lys Asn Pro Phe Asn Ser Ser
                 155                 160                 165

 Lys Leu Pro Glu Gly His Ser Ser Gln Gln Thr Lys Asn Glu Gln
                 170                 175                 180

 Ser Lys Asn Gly Arg Thr Gly Leu Phe Gln Thr Ser Lys Glu Asp
                 185                 190                 195

 Glu Leu Ser Glu Ser Lys Glu Lys Ser Thr Val Ala Asp Thr Ser
                 200                 205                 210

 Ile Gln Lys Leu Glu Lys Ser Lys Gln Thr Leu Pro Gly Leu Ser
                 215                 220                 225

 Asn Gly Ser Gln Ile Lys Ala Pro Ile Pro Lys Ala Arg Lys Met
                 230                 235                 240

 Ile Tyr Lys Ser Thr Asp Leu Asn Lys Asp Asp Asn Gln Ser Phe
                 245                 250                 255

 Pro Arg Gln Arg Thr Asp Ser Leu Lys Ala Arg Gly Ala Pro Arg
                 260                 265                 270

 Gly Ile Leu Lys Arg Asn Ser Ser Ser Ser Ser Thr Asp Ser Glu
                 275                 280                 285

 Thr Leu Arg Tyr Asn His Asn Phe Glu Pro Lys Ser Lys Ile Val
                 290                 295                 300

 Ser Pro Gly Leu Thr Ile His Glu Arg Ile Ser Glu Lys Glu His
                 305                 310                 315

 Ser Leu Glu Asp Asn Ser Ser Pro Asn Ser Leu Glu Pro Leu Lys
                 320                 325                 330

 His Val Arg Phe Ser Ala Val Lys Asp Glu Leu Pro Gln Ser Pro
                 335                 340                 345

 Gly Leu Ile His Gly Arg Glu Val Gly Glu Phe Ser Val Leu Glu
                 350                 355                 360

 Ser Asp Arg Leu Lys Asn Gly Met Glu Asp Ala Gly Asp Thr Glu
                 365                 370                 375

 Glu Phe Gln Ser Asp Pro Lys Pro Ser Gln Tyr Arg Lys Pro Ser
                 380                 385                 390

 Leu Phe His Gln Ser Thr Ser Ser Pro Tyr Val Ser Lys Ser Glu
                 395                 400                 405

 Thr His Gln Pro Met Thr Ser Gly Ser Phe Pro Ile Asn Gly Leu
                 410                 415                 420

 His Ser His Ser Glu Val Leu Thr Ala Arg Pro Gln Ser Met Glu
                 425                 430                 435

 Asn Ser Pro Thr Ile Asn Glu Pro Lys Asp Lys Ser Ser Glu Leu
                 440                 445                 450

 Thr Arg Leu Glu Ser Val Leu Pro Arg Ser Pro Ala Asp Glu Leu
                 455                 460                 465

 Ser His Cys Val Glu Pro Glu Pro Ser Gln Val Pro Gly Gly Ser
                 470                 475                 480

 Ser Arg Asp Arg Gln Gln Gly Ser Glu Glu Glu Pro Ser Pro Val
                 485                 490                 495

 Leu Lys Thr Leu Glu Arg Ser Ala Ala Arg Lys Met Pro Ser Lys
                 500                 505                 510

 Ser Leu Glu Asp Ile Ser Ser Asp Ser Ser Asn Gln Ala Lys Val
                 515                 520                 525

 Asp Asn Gln Pro Glu Glu Leu Val Arg Ser Ala Glu Asp Asp Glu
                 530                 535                 540

 Lys Pro Asp Gln Lys Pro Val Thr Asn Glu Cys Val Pro Arg Ile
                 545                 550                 555

 Ser Thr Val Pro Thr Gln Pro Asp Asn Pro Phe Ser His Pro Asp
                 560                 565                 570

 Lys Leu Lys Arg Met Ser Lys Ser Val Pro Ala Phe Leu Gln Asp
                 575                 580                 585

 Glu Val Ser Gly Ser Val Met Ser Val Tyr Ser Gly Asp Phe Gly
                 590                 595                 600

 Asn Leu Glu Val Lys Gly Asn Ile Gln Phe Ala Ile Glu Tyr Val
                 605                 610                 615

 Glu Ser Leu Lys Glu Leu His Val Phe Val Ala Gln Cys Lys Asp
                 620                 625                 630

 Leu Ala Ala Ala Asp Val Lys Lys Gln Arg Ser Asp Pro Tyr Val
                 635                 640                 645

 Lys Ala Tyr Leu Leu Pro Asp Lys Gly Lys Met Gly Lys Lys Lys
                 650                 655                 660

 Thr Leu Val Val Lys Lys Thr Leu Asn Pro Val Tyr Asn Glu Ile
                 665                 670                 675

 Leu Arg Tyr Lys Ile Glu Lys Gln Ile Leu Lys Thr Gln Lys Leu
                 680                 685                 690

 Asn Leu Ser Ile Trp His Arg Asp Thr Phe Lys Arg Asn Ser Phe
                 695                 700                 705

 Leu Gly Glu Val Glu Leu Asp Leu Glu Thr Trp Asp Trp Asp Asn
                 710                 715                 720

 Lys Gln Asn Lys Gln Leu Arg Trp Tyr Pro Leu Lys Arg Lys Thr
                 725                 730                 735

 Ala Pro Val Ala Leu Glu Ala Glu Asn Arg Gly Glu Met Lys Leu
                 740                 745                 750

 Ala Leu Gln Tyr Val Pro Glu Pro Val Pro Gly Lys Lys Leu Pro
                 755                 760                 765

 Thr Thr Gly Glu Val His Ile Trp Val Lys Glu Cys Leu Asp Leu
                 770                 775                 780

 Pro Leu Leu Arg Gly Ser His Leu Asn Ser Phe Val Lys Cys Thr
                 785                 790                 795

 Ile Leu Pro Asp Thr Ser Arg Lys Ser Arg Gln Lys Thr Arg Ala
                 800                 805                 810

 Val Gly Lys Thr Thr Asn Pro Ile Phe Asn His Thr Met Val Tyr
                 815                 820                 825

 Asp Gly Phe Arg Pro Glu Asp Leu Met Glu Ala Cys Val Glu Leu
                 830                 835                 840

 Thr Val Trp Asp His Tyr Lys Leu Thr Asn Gln Phe Leu Gly Gly
                 845                 850                 855

 Leu Arg Ile Gly Phe Gly Thr Gly Lys Ser Tyr Gly Thr Glu Val
                 860                 865                 870

 Asp Trp Met Asp Ser Thr Ser Glu Glu Val Ala Leu Trp Glu Lys
                 875                 880                 885

 Met Val Asn Ser Pro Asn Thr Trp Ile Glu Ala Thr Leu Pro Leu
                 890                 895                 900

 Arg Met Leu Leu Ile Ala Lys Ile Ser Lys
                 905                 910

<210> 4197
<211> 4451
<212> DNA
<213> Homo sapien

<400> 4197
 caaggagaaa ctatacagga acagacaaat ttctcagagg agtagaaaag 50

 aatgtgatgg ttgttagctg tgtttatcct tcttcagaga aaaacaattc 100

 caatagttta aatcgaatga atggtgttat gtttcctgga aattcaccaa 150

 gctatactga gaggtctaat ataaatgggc ctgggacacc caggccactt 200

 aatcgaccaa aggtttcttt gtcagccccc atgacaacaa atgggttgcc 250

 tgagagcaca gacagcaaag aggcaaattt gcagcaaaat gaggagaaaa 300

 atcacagcga ctcttccacc tctgaatcag aagtttcctc agtgagccct 350

 ttgaaaaata aacatccaga tgaagatgct gtggaagctg aggggcatga 400

 ggtaaaaaga ctcaggtttg acaaagaagg tgaagtcaga gaaacagcca 450

 gtcaaacgac ttccagcgaa atttcttcag ttatggtagg agaaacagaa 500

 gcatcatctt catctcagga taaagacaaa gatagccgtt gtacccggca 550

 gcactgtaca gaagaggatg aagaagagga tgaagaggaa gaagaagagt 600

 cttttatgac atcaagagaa atgatcccag aaagaaaaaa tcaagaaaaa 650

 gaatctgatg atgccttaac tgtgaatgaa gagacttctg aggaaaataa 700

 tcaaatggag gaatctgatg tgtctcaagc tgagaaagat ttgctacatt 750

 ctgaaggtag tgaaaacgag ggccctgtaa gtagtagttc ttctgactgc 800

 cgtgaaacag aagaattagt aggatccaat tccagtaaaa ctggagagat 850

 tctttcagaa tcatccatgg aaaatgatga cgaagccaca gaagtcaccg 900

 atgaaccaat ggaacaagac taactattta gaaacattta gatgcagtat 950

 tttacataca gttctggttt taacactgta taaaactttt gtgtaataaa 1000

 atggaccttt agttttacaa gagaagcagg ttgtaaaata aagtacttta 1050

 tggataattc ctgaaagagt tgtacatgta agaactgtga atatcagctc 1100

 ctctgggtcc tgcttacctt accgctgact tttctttctt tctttttttg 1150

 gtctgggcaa atcagtggtt tgtgtataga tttttttttt tttttttaat 1200

 ttaggattga agtttttaaa ctggaaggta attacaattt tgaaaagttt 1250

 tttgagatta tcacatttag tttatacata tgcaagaagc tttttgtctt 1300

 gtctctttct gatagctcta gcagttttca tattttggtc atagtttcaa 1350

 cattttaaca tgtgaattat agggtttcat gctggtttcc agattttatt 1400

 gtttggctac gtacaatgga actttaagtc atatatacat acatacatat 1450

 atatatatat atatatatat atatatatat aattctaagg ggggaaatgt 1500

 aatatttttc tgtttctata agagatgaat acagtggata ctttttctat 1550

 tggtaatgat tgagttcacc tctttcagaa gacattttct ttctcttctg 1600

 agtaattgaa ataaaatctg gcccttgtga aaccctggaa atcttaagtc 1650

 tgttgaaata ccaggttaaa cacattccaa gagatctgtt caaactcaaa 1700

 ttcttttgta tacttctgag gtgcctgaga aaaagacttc attatttatg 1750

 agaaaatatg ctttatcttg gaaattgtgt tcaaatgtta gcttactatt 1800

 ttgtagaatg aatgtttatg aagctgatat gagaccatct cagaagaacc 1850

 aagcaggttc cttgaccttt tgcttgcttt tctgaacatt gtgaatatta 1900

 cacatgtctt tctaaattat tctagggtat gcaaatgtca atggtatgaa 1950

 acaccactgt actggaagaa ttaatatatt actttagtat gtacctgagc 2000

 taaatgactg aagctttagg ggtgcataga aaccaccata atttgtatga 2050

 cattttgaag tgaattaaat atttttgaac atgcttcttc gacagccagt 2100

 gttatatttt tcagatcaac acaaagcaca atgattactc gaaattcagt 2150

 attttcaaat ttacatattt aaagtcatgc aagctgtaac ttccctgtca 2200

 aaattactgg ctgccaaatt tatacctgtt tcttcagctg taccttttga 2250

 tatttaaagt ttttaaattt ctgtaaagta gattttgtag aatgtaatgt 2300

 gttcactgcc tttgtgaagc ggtatataat tgtataattt ctgtgtgtaa 2350

 actgaatgct tgggctttca atacagtatt catataaagc aataaatatt 2400

 aatgttatga aatatttgac tacattttta tcaaaatatg aaagaatccc 2450

 ccctttttta gtttcagata cctgaactac acagatgagc ttctaaaact 2500

 gatgcaaaca gtttctgaca ctgtataata tgcttttggg tgatttgggg 2550

 ggcaaccaca agttttgcgt tttgactact taaatcatca tggctataaa 2600

 taccaaaacg atttggatcc atttatgttt gtaggataat atactactga 2650

 ctgacttgac tgtcaggttc acaacagcta gatgatatat ttatgactat 2700

 gtctaatagt tgaaataaaa tctgaatatt gatttactat acccaagagg 2750

 ggagaaaaat taaccattgt aaatttttaa aaattttttc aaaaatgtta 2800

 aaatgaggca aatttaagtt tacaaatttt gaaattttct tttgaatatt 2850

 tatgaaattg tcagtaaact tacctaagat cctgtgacct tttgatattt 2900

 tttattttaa ttgtagtgcc atggaccatt tgtaaacaaa ttgatttact 2950

 tttgttggtt gtaagttgaa gatttagcat tatgactttg aggtctgtgg 3000

 ttttatttgt aaacttgcaa ttgctatatt tgcaagggca aatgtatttc 3050

 tttattaaat aaagtacaat aatggtgaat gtaccaaaat gacatcactt 3100

 aactctatga gagatctgca ttttaatcta tagtttaata gttttaatat 3150

 ttattagata ttcatatgtt gatcatagat caaacttgtt gctgtttata 3200

 cagataattg tagaatgctc atggaatatc tttagggtag gtggaatact 3250

 tctgtagtta aattgggaaa ccttgttcag ctggttttag atattgatgg 3300

 ccatttggaa gtaaatttcc gcaggtattc ataggtgcac ttaacacaga 3350

 ctttgcttaa tgaaaatgtc agttctaata gtaactgatt cacttctgaa 3400

 cagaagtgat tttaggcata tttcttaaca tatatcaagc aaagtcctgt 3450

 taaaagatct aaatgaagaa tggagacctc agtgattaaa gatattttgt 3500

 ttctgacctt gagcagattg cttacctgtt ctctagacta taacccaaca 3550

 tgtaaaaaaa atttgaagat ggtgatgagg aaagtgagat atatatatat 3600

 atatgtatta tgtttctagc acttttccct tttaaaaagt gaaaatatcc 3650

 ttgtacattt ttgaaaaata tattttcagt tctgaaaaat gtagcagaag 3700

 tagtgaaaat gtcatatttt aaatgttgat tattagataa atttaacctg 3750

 cttagggttt attgtaacta cacctttcag acgtgtgttt tggagtagtg 3800

 gaattgccag ccaggccctg tggcttggaa aggcatccca gaaatcctcg 3850

 gccagaaggt gtggcttgtt aaagcattga gattcagagt attttgtttt 3900

 gccggtgtag ataggcatgt atttatgcat ttttgcattt gtaaaatcaa 3950

 cttttcaaat aatgtaaatg taatatacta gtttacttaa aggtacttgg 4000

 gcagaatcta aagctgctac aatgtttgat tatgaaaaaa atgtaacatg 4050

 gtaaggatga aaatgcaact tacaaaacca aaggaattaa aaattttcgg 4100

 tagtgtttca aattgtcttc tgaacaggaa tttaacattg gttttgatga 4150

 agtgagggtc agttctcaag atttgtgcta atcataaaat gaatgaatgc 4200

 aaaacacctt gtaatttcat atggaattat aaaaattagg tttgctgggt 4250

 tttggcctaa taagagtgct agtatgtatt ggttagaata catcttacta 4300

 tttcacattt taaaaatcag tacactcttc aggattttct tttatttcaa 4350

 cttggagcct agattacttt gccaaatgta ttattttcat aatgcaataa 4400

 aatataaatt agaataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4450

 a 4451

<210> 4198
<211> 306
<212> PRT
<213> Homo sapien

<400> 4198
 Arg Arg Asn Tyr Thr Gly Thr Asp Lys Phe Leu Arg Gly Val Glu
   1               5                  10                  15

 Lys Asn Val Met Val Val Ser Cys Val Tyr Pro Ser Ser Glu Lys
                  20                  25                  30

 Asn Asn Ser Asn Ser Leu Asn Arg Met Asn Gly Val Met Phe Pro
                  35                  40                  45

 Gly Asn Ser Pro Ser Tyr Thr Glu Arg Ser Asn Ile Asn Gly Pro
                  50                  55                  60

 Gly Thr Pro Arg Pro Leu Asn Arg Pro Lys Val Ser Leu Ser Ala
                  65                  70                  75

 Pro Met Thr Thr Asn Gly Leu Pro Glu Ser Thr Asp Ser Lys Glu
                  80                  85                  90

 Ala Asn Leu Gln Gln Asn Glu Glu Lys Asn His Ser Asp Ser Ser
                  95                 100                 105

 Thr Ser Glu Ser Glu Val Ser Ser Val Ser Pro Leu Lys Asn Lys
                 110                 115                 120

 His Pro Asp Glu Asp Ala Val Glu Ala Glu Gly His Glu Val Lys
                 125                 130                 135

 Arg Leu Arg Phe Asp Lys Glu Gly Glu Val Arg Glu Thr Ala Ser
                 140                 145                 150

 Gln Thr Thr Ser Ser Glu Ile Ser Ser Val Met Val Gly Glu Thr
                 155                 160                 165

 Glu Ala Ser Ser Ser Ser Gln Asp Lys Asp Lys Asp Ser Arg Cys
                 170                 175                 180

 Thr Arg Gln His Cys Thr Glu Glu Asp Glu Glu Glu Asp Glu Glu
                 185                 190                 195

 Glu Glu Glu Glu Ser Phe Met Thr Ser Arg Glu Met Ile Pro Glu
                 200                 205                 210

 Arg Lys Asn Gln Glu Lys Glu Ser Asp Asp Ala Leu Thr Val Asn
                 215                 220                 225

 Glu Glu Thr Ser Glu Glu Asn Asn Gln Met Glu Glu Ser Asp Val
                 230                 235                 240

 Ser Gln Ala Glu Lys Asp Leu Leu His Ser Glu Gly Ser Glu Asn
                 245                 250                 255

 Glu Gly Pro Val Ser Ser Ser Ser Ser Asp Cys Arg Glu Thr Glu
                 260                 265                 270

 Glu Leu Val Gly Ser Asn Ser Ser Lys Thr Gly Glu Ile Leu Ser
                 275                 280                 285

 Glu Ser Ser Met Glu Asn Asp Asp Glu Ala Thr Glu Val Thr Asp
                 290                 295                 300

 Glu Pro Met Glu Gln Asp
                 305

<210> 4199
<211> 2749
<212> DNA
<213> Homo sapien

<400> 4199
 gccaaagctg taattgaact tcttgaaaaa tcaggtgtca acctagatgg 50

 aaagaagatt ttggtagtgg gggcccatgg gtctttggaa gctgctctac 100

 aatgcctgtt ccagagaaaa gggtccatga caatgagcat ccagtggaaa 150

 acacgccagc ttcaaagcaa gcttcacgag gctgacattg tggtcctagg 200

 ctcacctaag ccagaagaga ttccccttac ttggatacaa ccaggaacta 250

 ctgttctcaa ctgctcccat gacttcctgt cagggaaggt tgggtgtggc 300

 tctccaagaa tacattttgg tggactcatt gaggaagatg atgtgattct 350

 ccttgctgca gctctgcgaa ttcagaacat ggtcagtagt ggaaggagat 400

 ggcttcgtga acagcagcac aggcggtgga gacttcactg cttgaaactt 450

 cagcctctct cccctgtgcc aagtgacatt gagatttcaa gaggacaaac 500

 tccaaaagct gtggatgtcc ttgccaagga gattggattg cttgcagatg 550

 aaattgaaat ctatggcaaa agcaaagcca aagtacgttt gtccgtgcta 600

 gaaaggttaa aggatcaagc agatggaaaa tacgtcttag ttgctgggat 650

 cacacccacc cctcttggag aagggaagag cacagtcacc atcgggcttg 700

 tgcaggctct gaccgcacac ctgaatgtca actcctttgc ctgcttgagg 750

 cagccttccc aaggaccgac gtttggagtg aaaggaggag ccgcgggtgg 800

 tggatatgcc caggtcatcc ccatggagga gttcaacctt cacttgactg 850

 gagacatcca cgccatcacc gctgccaata acttgctggc tgccgccatc 900

 gacacgagga ttcttcatga aaacacgcaa acagataagg ctctgtataa 950

 tcggctggtt cctttagtga atggtgtcag agaattttca gaaattcagc 1000

 ttgctcggct aaaaaaactg ggaataaata agactgatcc gagcacactg 1050

 acagaagagg aagtgagtaa atttgcccgt ctcgacatcg acccatctac 1100

 catcacgtgg cagagagtat tggatacaaa tgaccgattt ctacgaaaaa 1150

 taaccatcgg gcagggaaac acagagaagg gccattaccg gcaggcgcag 1200

 tttgacatcg cagtggccag cgagatcatg gcggtgctgg ccctgacgga 1250

 cagcctcgca gacatgaagg cacggctggg aaggatggtg gtggccagtg 1300

 acaaaagcgg gcagcctgtg acagcagatg atttgggggt gacaggtgct 1350

 ttgacagttt tgatgaaaga tgcaataaaa ccaaacctga tgcagaccct 1400

 ggaagggaca cctgtgttcg tgcatgcggg cccttttgct aacattgctc 1450

 acggcaactc ttcagtgttg gctgataaaa ttgccctgaa actggttggt 1500

 gaagaaggat ttgtagtgac cgaagctggc tttggtgctg acatcggaat 1550

 ggagaaattc ttcaacatca agtgccgagc ttccggcttg gtgcccaacg 1600

 tggttgtgtt agtggcaacg gtgcgagctc tgaagatgca tggaggcggg 1650

 ccaagtgtaa cggctggtgt tcctcttaag aaagaatata cagaggagaa 1700

 catccagctg gtggcagacg gctgctgtaa cctccagaag caaattcaga 1750

 tcactcagct ctttggggtt cccgttgtgg tggctctgaa tgtcttcaag 1800

 accgacaccc gcgctgagat tgacttggtg tgtgagcttg caaagcgggc 1850

 tggtgccttt gatgcagtcc cctgctatca ctggtcggtt ggtggaaaag 1900

 gatcggtgga cttggctcgg gctgtgagag aggctgcgag taaaagaagc 1950

 cgattccagt tcctgtatga tgttcaggtt ccaattgtgg acaagataag 2000

 gaccattgct caggctgtct atggagccaa agatattgaa ctctctcctg 2050

 aggcacaagc caaaatagat cgttacactc aacagggttt tggaaatttg 2100

 cccatctgca tggcaaagac ccacctttct ctatctcacc aacctgacaa 2150

 aaaaggtgtg ccaagggact tcatcttacc tatcagtgac gtccgggcca 2200

 gcataggcgc tgggttcatt taccctttgg tcggaacgat gagcaccatg 2250

 ccaggactgc ccacccggcc ctgcttttat gacatagatc ttgataccga 2300

 aacagaacaa gttaaaggct tgttctaagt ggacaaggct ctcacaggac 2350

 ccgatgcaga ctcctgaaac agactactct ttgccttttt gctgcagttg 2400

 gagaagaaac tgaatttgaa aaatgtctgt tatgcaatgc tggagacgtg 2450

 gtgaaatagg ccaaagattt cttcttcgtt caagatgaat tctgttcaca 2500

 gtggagtatg gtgttcggca aaaggacctc caccaagact gaaagaaact 2550

 aatttatttc tgtttctgtg gagtttccat tatttctact gcttacactt 2600

 tagaatgttt attttatggg gactaaggga ttaggagtgt gaactaaaag 2650

 gtaacatttt ccactctcaa gttttctact ttgtctttga actgaaaata 2700

 aacatggatc tagaaaccca aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2749

<210> 4200
<211> 733
<212> PRT
<213> Homo sapien

<400> 4200
 Met Thr Met Ser Ile Gln Trp Lys Thr Arg Gln Leu Gln Ser Lys
   1               5                  10                  15

 Leu His Glu Ala Asp Ile Val Val Leu Gly Ser Pro Lys Pro Glu
                  20                  25                  30

 Glu Ile Pro Leu Thr Trp Ile Gln Pro Gly Thr Thr Val Leu Asn
                  35                  40                  45

 Cys Ser His Asp Phe Leu Ser Gly Lys Val Gly Cys Gly Ser Pro
                  50                  55                  60

 Arg Ile His Phe Gly Gly Leu Ile Glu Glu Asp Asp Val Ile Leu
                  65                  70                  75

 Leu Ala Ala Ala Leu Arg Ile Gln Asn Met Val Ser Ser Gly Arg
                  80                  85                  90

 Arg Trp Leu Arg Glu Gln Gln His Arg Arg Trp Arg Leu His Cys
                  95                 100                 105

 Leu Lys Leu Gln Pro Leu Ser Pro Val Pro Ser Asp Ile Glu Ile
                 110                 115                 120

 Ser Arg Gly Gln Thr Pro Lys Ala Val Asp Val Leu Ala Lys Glu
                 125                 130                 135

 Ile Gly Leu Leu Ala Asp Glu Ile Glu Ile Tyr Gly Lys Ser Lys
                 140                 145                 150

 Ala Lys Val Arg Leu Ser Val Leu Glu Arg Leu Lys Asp Gln Ala
                 155                 160                 165

 Asp Gly Lys Tyr Val Leu Val Ala Gly Ile Thr Pro Thr Pro Leu
                 170                 175                 180

 Gly Glu Gly Lys Ser Thr Val Thr Ile Gly Leu Val Gln Ala Leu
                 185                 190                 195

 Thr Ala His Leu Asn Val Asn Ser Phe Ala Cys Leu Arg Gln Pro
                 200                 205                 210

 Ser Gln Gly Pro Thr Phe Gly Val Lys Gly Gly Ala Ala Gly Gly
                 215                 220                 225

 Gly Tyr Ala Gln Val Ile Pro Met Glu Glu Phe Asn Leu His Leu
                 230                 235                 240

 Thr Gly Asp Ile His Ala Ile Thr Ala Ala Asn Asn Leu Leu Ala
                 245                 250                 255

 Ala Ala Ile Asp Thr Arg Ile Leu His Glu Asn Thr Gln Thr Asp
                 260                 265                 270

 Lys Ala Leu Tyr Asn Arg Leu Val Pro Leu Val Asn Gly Val Arg
                 275                 280                 285

 Glu Phe Ser Glu Ile Gln Leu Ala Arg Leu Lys Lys Leu Gly Ile
                 290                 295                 300

 Asn Lys Thr Asp Pro Ser Thr Leu Thr Glu Glu Glu Val Ser Lys
                 305                 310                 315

 Phe Ala Arg Leu Asp Ile Asp Pro Ser Thr Ile Thr Trp Gln Arg
                 320                 325                 330

 Val Leu Asp Thr Asn Asp Arg Phe Leu Arg Lys Ile Thr Ile Gly
                 335                 340                 345

 Gln Gly Asn Thr Glu Lys Gly His Tyr Arg Gln Ala Gln Phe Asp
                 350                 355                 360

 Ile Ala Val Ala Ser Glu Ile Met Ala Val Leu Ala Leu Thr Asp
                 365                 370                 375

 Ser Leu Ala Asp Met Lys Ala Arg Leu Gly Arg Met Val Val Ala
                 380                 385                 390

 Ser Asp Lys Ser Gly Gln Pro Val Thr Ala Asp Asp Leu Gly Val
                 395                 400                 405

 Thr Gly Ala Leu Thr Val Leu Met Lys Asp Ala Ile Lys Pro Asn
                 410                 415                 420

 Leu Met Gln Thr Leu Glu Gly Thr Pro Val Phe Val His Ala Gly
                 425                 430                 435

 Pro Phe Ala Asn Ile Ala His Gly Asn Ser Ser Val Leu Ala Asp
                 440                 445                 450

 Lys Ile Ala Leu Lys Leu Val Gly Glu Glu Gly Phe Val Val Thr
                 455                 460                 465

 Glu Ala Gly Phe Gly Ala Asp Ile Gly Met Glu Lys Phe Phe Asn
                 470                 475                 480

 Ile Lys Cys Arg Ala Ser Gly Leu Val Pro Asn Val Val Val Leu
                 485                 490                 495

 Val Ala Thr Val Arg Ala Leu Lys Met His Gly Gly Gly Pro Ser
                 500                 505                 510

 Val Thr Ala Gly Val Pro Leu Lys Lys Glu Tyr Thr Glu Glu Asn
                 515                 520                 525

 Ile Gln Leu Val Ala Asp Gly Cys Cys Asn Leu Gln Lys Gln Ile
                 530                 535                 540

 Gln Ile Thr Gln Leu Phe Gly Val Pro Val Val Val Ala Leu Asn
                 545                 550                 555

 Val Phe Lys Thr Asp Thr Arg Ala Glu Ile Asp Leu Val Cys Glu
                 560                 565                 570

 Leu Ala Lys Arg Ala Gly Ala Phe Asp Ala Val Pro Cys Tyr His
                 575                 580                 585

 Trp Ser Val Gly Gly Lys Gly Ser Val Asp Leu Ala Arg Ala Val
                 590                 595                 600

 Arg Glu Ala Ala Ser Lys Arg Ser Arg Phe Gln Phe Leu Tyr Asp
                 605                 610                 615

 Val Gln Val Pro Ile Val Asp Lys Ile Arg Thr Ile Ala Gln Ala
                 620                 625                 630

 Val Tyr Gly Ala Lys Asp Ile Glu Leu Ser Pro Glu Ala Gln Ala
                 635                 640                 645

 Lys Ile Asp Arg Tyr Thr Gln Gln Gly Phe Gly Asn Leu Pro Ile
                 650                 655                 660

 Cys Met Ala Lys Thr His Leu Ser Leu Ser His Gln Pro Asp Lys
                 665                 670                 675

 Lys Gly Val Pro Arg Asp Phe Ile Leu Pro Ile Ser Asp Val Arg
                 680                 685                 690

 Ala Ser Ile Gly Ala Gly Phe Ile Tyr Pro Leu Val Gly Thr Met
                 695                 700                 705

 Ser Thr Met Pro Gly Leu Pro Thr Arg Pro Cys Phe Tyr Asp Ile
                 710                 715                 720

 Asp Leu Asp Thr Glu Thr Glu Gln Val Lys Gly Leu Phe
                 725                 730

<210> 4201
<211> 6123
<212> DNA
<213> Homo sapien

<400> 4201
 cgactggctg gtcccctggc cgtgagccgg cttctgaatg atttatgccg 50

 ccttgaactt gactccagcg tgacaggagt gagaagagcc gctcccgcta 100

 gaggaaagct ggaaaccgta ctgtgctcac cacataacct ctgggtgctg 150

 gaaatggagt attactactg ccccagcctg ctgaagctct tgcgctacct 200

 ctgggaccag ctgaagcagt gtttctcccg gcagcccact gaacccaagg 250

 acactgacac cctcgtgcac gaagccggca gccagtatgg gacgtggaca 300

 gagcagtgcc agagtgggga gagcttggcc actgagtccc cagatagcag 350

 tgccacatcg acaaggaaac agccccccag cagccgtttg tcttctctgt 400

 cctcccaaac ggagcccacc tcggcagggg accagtatga ctgctccagg 450

 gaccagcgga gcaccagcgt ggaccactcc agcactgacc tggaatccac 500

 cgatgggatg gaggggccgc ctccaccgga cgcctgccct gaaaagagag 550

 tagatgactt ctccttcatt gatcaaacct cagtcctcga ctcaagtgcc 600

 ctcaagaccc gggtgcagct cagcaagaga agccgccgcc gggcccccat 650

 ctcccactcc ctccggcgca gccgatttag tgagtccgag agcagatcac 700

 ctttggagga tgagactgac aacacgtgga tgttcaaaga ctcaacggag 750

 gagaaatcac ccaggaagga agagtcggat gaggaggaga cggcatccaa 800

 agctgagagg acccccgtca gccatcctca gaggatgcct gcgtttccag 850

 gcatggatcc ggcagtgcta aaggctcagc tgcacaagag gccagaggtg 900

 gacagtcctg gcgagacccc cagctgggca ccccaaccca agagccccaa 950

 gtcccccttc cagcctgggg tgctgggcag tcgcgtgctg ccttccagca 1000

 tggacaagga tgagaggtcg gatgaaccct ctccccagtg gctaaaggaa 1050

 ttgaaatcca agaagaggca aagtctttat gagaaccaag tttgaccagg 1100

 cagggaacac tgccacatct acgtaacaga agccttaacc atcagaaccc 1150

 gcagacgagg ccgagctgct gccgtttctt cctgcacaac gcttacgtgc 1200

 ctgggccctt cccattggat tgagaacgct atccagtgcc cctgtcctcg 1250

 ccaggctctc cctggatcca gacgggaaga cccaacctcc aggagcactc 1300

 gctcatctcc ccagacagca cttcaggctg ggaaaggagc caggctgccc 1350

 agaaacgtcc atgtgggtgg ttttgctttt tatgtaaaaa tttgcatttc 1400

 tacctatttt agacaccttc atcagctcca agaacatcag tgtgaggctg 1450

 gaattgtctc cccaggttct gaaaaacacc tgcatttgtg aaagcacctc 1500

 ctcacccgac cccggggcag gtcttttttt ggaaggacat ttccaaggaa 1550

 gatcaaactg ttcattttct gctgtagtct cggtgcaggg tattaccgct 1600

 gggttgaggt tttctattct ttttttttgg tgagttcctt cttccccttg 1650

 aggaatcagc agttccaatt tttaaacata ctctccctga ttatgtgtat 1700

 ttctctttct agtggggctg tgtgcatcgt tggcctatgt tattgtatgt 1750

 catttttgtt tgctttagaa ggcgataaag caataattca gctaattttc 1800

 tttgaaactt gataggtata tatgtgttta cgttaaagga caggaggaaa 1850

 gatgtgcgaa taatttgttc tgaagtatcc agtcacctca ggttatctta 1900

 tccctatcca agctgtttag aagttataat tgtcactctt gtatttattt 1950

 ccatggcttc ttttcatttg agctctggtt tcagtagggt gacctttgcc 2000

 ccttggcctt aagggttcat aaactgcagc ccaagtggtg gtgcctttgc 2050

 ttatgaatca tcagacctgc cctagtaatc tttttctcca gagtcttctt 2100

 tgaacatgat gtgggctgct ggcatggagg agttgttcca aactggcctc 2150

 agaacagatg catgaatgaa gggtactttt tgcttttgct cacctcattt 2200

 tccttcatct ttcttgatga atccattatt tgcaaatgct gtcaaaacat 2250

 gctttccttc tccctggcca cctctcagga gttcatttgt ctctctatct 2300

 cagcttcctc cctcatcttc ctttacccct cttctctgtc ttagtgggtg 2350

 gatgggcatg gatagaaatc ctctgtttct ttaggttagg ataaacacct 2400

 gggccctggt gaggcagttg ctgttcagca ccagggacag caactgcagg 2450

 gctgtgaggc cggagcccac cttgtgtcct gttcgatgag ctttggttac 2500

 tgatgagcaa ttgccagacc atgtcaccca cccagccttt tacacctggg 2550

 agcctcatgc atctgggttt gggagtttgg ccctgctgat gatagtttgt 2600

 tttctcttca ttccctgaat tagtcatcag ttctccgtgg ccatttgggg 2650

 attcatgcct gcaactgctt cagttgaatt cttttttaaa gatccagttt 2700

 atgttttata ataattttga tcttatggct ttcaacgtca ataggatccc 2750

 ctttaaaaat accctgctag tgttttgttt tgttttgttt ttctgagaca 2800

 aggtcttact ctgttgctca agctggagtg gagtggcacg atcatagctc 2850

 actaacacct gggctcaagt gattctccca cctcagcctc ccaagtagct 2900

 gggactacag gtgtatgcta ccatgaccag ctaattttta aatatttttg 2950

 tagagacaag ggtcttacca tgttgcccag gctggtctcg aacttctggg 3000

 ctcaagcaat tgtccctcct cagcctccca aagtgctcgg attacagaca 3050

 tgagccactg cacctggcct gaaacacatt cctagtcttt tgatcctgac 3100

 ttcttatctg ggctgctgtc tctctttcct tcaggtggaa aggacccctt 3150

 ggtaccatct caagcagtag gaaaggacct gctcttacat atattgatgg 3200

 tcctcatgca aaactctcaa ttcttaatta gtcatgtctc agctcaagga 3250

 tatcagacag gaatgaaaca cacttgaaaa tgagattgac ctggagattt 3300

 tttttcccta atctctcata ccttaattgg aaaaataatc aattaattct 3350

 atgttaatta ggatatacaa agttcaccct ccttgaaagt gactagggca 3400

 agccctgaag atcttcctca cctcctttta tttttctata accttgtctc 3450

 ctccagcacc acagggaaga caatcacagt gggtcaagag cttcacgtgg 3500

 gctctgccat gacctctgag acctgcttat gatcagtgca atgaagttag 3550

 aagtaactga tgattgggag cctttgcaga tagctgggca aatgggtgat 3600

 ttacttatcc ccattctaaa tggagtgagc tctctttgag gctaagcaag 3650

 gaggcgttgt atgctagttt ctagactttg cctggagacc cctttggaaa 3700

 tctgtcttct ttttaaactc acttaatatg ccttaatcat ctgtgtgtaa 3750

 tggagtcatc cgctcctcaa tctaaccctc ctcccctggg gctttggctg 3800

 tcctcaatga gagtttcatg cagaatggaa aatcctctat atgtacaatc 3850

 tctctccccc tcatttctct tcctcctcac ctccaccacc cctttgcaca 3900

 tcagcatttt aacagctggt cttttgagaa gcctgtatcc ttttcctctt 3950

 cagtagatac ccttcttcat ggtcctttgc ctaatcaaac agaggccttt 4000

 ggcctttgaa aatccatgac aaggcctcag aaatcagtgt tgtggaggat 4050

 tactccatgc caccggagaa actctggtga aagagaaacc tcgtggtctt 4100

 taggatgttg ggattttgag tgaacctgac ctgatagcct caggattcag 4150

 ggaaaggaca atcagatggc ggtgttttcc agggggacgc gccaaatcat 4200

 gtggtttcag acaattgtgt ttgcctttgt gcctccctgg aagggaggcc 4250

 aactaagggt atcaccaaga agccaaaaga gaaataggca tgagcctgtg 4300

 gttttaaact ttacaggctg ggcaaaggat ttagaaagac ccttagcatg 4350

 attttcctaa aagagacctt agctgctcca acctggtgct gatagctgct 4400

 ttgttgatct atgctttaaa atttttcttt ataatgcccc cagatggctc 4450

 ctggaactag tcgtaattgc aaactgtaaa aatccctcct ccccagtgta 4500

 gatatttaaa ccagagtaag tgaggggaga cattctgtgg tctctgaatg 4550

 tgccttcccc ctcatcgtgt gttaaaacac aaaagccgaa gttccatggc 4600

 gtcatgattc cgaggggctg gagggatagg acccactcca catctaaagg 4650

 ggatctgctt tgggctcggt cccattagcg agtgggggac tcttgctgtg 4700

 tgctaagagg ctgctaggac tcacccagtt ggaattctgg gtgggctcag 4750

 gaagtttaga gccacgtaaa aagctggtag gcatgagtgt gccaggtctt 4800

 tgccagcctg cgtctccttt tgcacccccc aatccagagt ttgctttctt 4850

 ttgactaaat tggctcctgc agggggaagg gcagaaagct aggccctctg 4900

 ctctggaaag tcggcctgag gtttccggca agttaaccct taaaatggac 4950

 acccctcagc ccgccctccc ctttggcctt cccagaatct ccttcagtgg 5000

 ttgctctcac acctgtgcca taacatcatc ttccatgact tggacgggca 5050

 cttccttgac aattcctatt ggcatcacac gggctacaaa ttatgctgtt 5100

 ttctaaagaa tttgaacttt tttttttttc ttttcttgag acacggtctt 5150

 gctctgttgg ccaggctgga atgcagtggc acaatcatag ctcactccag 5200

 cctccaactc ctgggctcaa gcaatcctct catctccacc tccagagtag 5250

 cctagatgac aggcgcacat caccacgccc agctgatctt ttaaatctgt 5300

 tttgtagaaa caggatctca ctatattgcc caagctggtc ttaaacttgg 5350

 tctcaagtga ttctactgcc tcagcctccc aaagtgctgg gattacaggc 5400

 ctgagccacc atgcccagct gaatttgagc tttttaataa tctcattcca 5450

 catagcctta tagatcctgt aaataggggg ggtcacaaaa gtaatatatt 5500

 gtgttatgga agataatttt gtactgtgct gtttcctaaa tcataccaat 5550

 atcctaaagt catgcacttc ccagatgatc gtgatcctcc aaatgctttg 5600

 taagatgggg cagggcgtgg aaatatatat atatacacac acacacagag 5650

 acacacacac acacaagtat agtatatatt ttcctaacct ttcttctggg 5700

 tccttcctca gatctttgag tcacgataga aaaggagctc gagttctttg 5750

 tgtaggaaag ttaagcttcc tgcctgcggt gttcttgcaa ttgccttagg 5800

 aattcacaag ctctaggagt tctgaacgga aggcagacga gaggcacttt 5850

 atccagtccc agaaagaatc tctaaccgtg tgactgagaa gtcatctaga 5900

 aaaacttata tttttaatgt aaaaacaaat ggggcttacc agacctcaca 5950

 gagtattgga cgtctacaag tgcttttata ttttgtaact gtaaagaagt 6000

 ttcatatgca cagaagagca gttggaaatc tggtcgactg caataaaaca 6050

 agatgacctt tgcatgtaca aagatgttgc attcagacta tgaaaatagc 6100

 aaataaagct ttggtgcaag ttg 6123

<210> 4202
<211> 364
<212> PRT
<213> Homo sapien

<400> 4202
 Arg Leu Ala Gly Pro Leu Ala Val Ser Arg Leu Leu Asn Asp Leu
   1               5                  10                  15

 Cys Arg Leu Glu Leu Asp Ser Ser Val Thr Gly Val Arg Arg Ala
                  20                  25                  30

 Ala Pro Ala Arg Gly Lys Leu Glu Thr Val Leu Cys Ser Pro His
                  35                  40                  45

 Asn Leu Trp Val Leu Glu Met Glu Tyr Tyr Tyr Cys Pro Ser Leu
                  50                  55                  60

 Leu Lys Leu Leu Arg Tyr Leu Trp Asp Gln Leu Lys Gln Cys Phe
                  65                  70                  75

 Ser Arg Gln Pro Thr Glu Pro Lys Asp Thr Asp Thr Leu Val His
                  80                  85                  90

 Glu Ala Gly Ser Gln Tyr Gly Thr Trp Thr Glu Gln Cys Gln Ser
                  95                 100                 105

 Gly Glu Ser Leu Ala Thr Glu Ser Pro Asp Ser Ser Ala Thr Ser
                 110                 115                 120

 Thr Arg Lys Gln Pro Pro Ser Ser Arg Leu Ser Ser Leu Ser Ser
                 125                 130                 135

 Gln Thr Glu Pro Thr Ser Ala Gly Asp Gln Tyr Asp Cys Ser Arg
                 140                 145                 150

 Asp Gln Arg Ser Thr Ser Val Asp His Ser Ser Thr Asp Leu Glu
                 155                 160                 165

 Ser Thr Asp Gly Met Glu Gly Pro Pro Pro Pro Asp Ala Cys Pro
                 170                 175                 180

 Glu Lys Arg Val Asp Asp Phe Ser Phe Ile Asp Gln Thr Ser Val
                 185                 190                 195

 Leu Asp Ser Ser Ala Leu Lys Thr Arg Val Gln Leu Ser Lys Arg
                 200                 205                 210

 Ser Arg Arg Arg Ala Pro Ile Ser His Ser Leu Arg Arg Ser Arg
                 215                 220                 225

 Phe Ser Glu Ser Glu Ser Arg Ser Pro Leu Glu Asp Glu Thr Asp
                 230                 235                 240

 Asn Thr Trp Met Phe Lys Asp Ser Thr Glu Glu Lys Ser Pro Arg
                 245                 250                 255

 Lys Glu Glu Ser Asp Glu Glu Glu Thr Ala Ser Lys Ala Glu Arg
                 260                 265                 270

 Thr Pro Val Ser His Pro Gln Arg Met Pro Ala Phe Pro Gly Met
                 275                 280                 285

 Asp Pro Ala Val Leu Lys Ala Gln Leu His Lys Arg Pro Glu Val
                 290                 295                 300

 Asp Ser Pro Gly Glu Thr Pro Ser Trp Ala Pro Gln Pro Lys Ser
                 305                 310                 315

 Pro Lys Ser Pro Phe Gln Pro Gly Val Leu Gly Ser Arg Val Leu
                 320                 325                 330

 Pro Ser Ser Met Asp Lys Asp Glu Arg Ser Asp Glu Pro Ser Pro
                 335                 340                 345

 Gln Trp Leu Lys Glu Leu Lys Ser Lys Lys Arg Gln Ser Leu Tyr
                 350                 355                 360

 Glu Asn Gln Val


<210> 4203
<211> 1697
<212> DNA
<213> Homo sapien

<400> 4203
 ctgtttatag ataatgtctg cagtttctgt ttgagagaga taattatgac 50

 acttagcatt ggaaaactaa gaagaacgta agcaggtcag ctatcagaag 100

 tcttcagact ggagagattc ctggaggggg agtggccctt taatccatca 150

 gctgaagcca tctggtagga cgctcgttgc agaaatggtt agttctgaaa 200

 tgttgtagct cagcaacatc actgaatgtc acagaattga caggcacgga 250

 gctaaaaggg cctctagcca cccccacaac tccgctctac ctctgtctcc 300

 ctaacacatg acttggaaca aatacactct aggtacaaag atggctacct 350

 gaagtttatg atccctactc atggagctgc ttgaggactt cacatttttt 400

 aaaaagctgc tttgggcacc cccattcctg aggagttttg tagcttggtt 450

 tctctttgcc acattacgtt tgtaagacta acattttata accataagca 500

 gttaggcctt tttattttga gaaatttatc tgtagcttcc ttttatttac 550

 acttggggac tatttttaag taaccgattg aaatattttt gtttctccat 600

 tgcaagtgaa atccttgttg ctaatctttt gccacatgta aaattgttca 650

 cttgttatca agcaggtagt tcaatatctg taattcttga gttcttttca 700

 actagcatga tgctaggtgt cactcactgt tttttaattg tgggagattg 750

 atgcgtcagt gcatgaagtg gggggtggtc accagcatct aactcaaagt 800

 gtgattatag ctatcttacc acattttttt tttctttctc actctgtcac 850

 ccaggctgga gtgcagtggt gtaatctcag ctcactgcag cctcgacctc 900

 ctgggctcaa gcgatcctcc tacctcagcc tcccaaatag ctgggaccac 950

 aggcgcatgc caccccacta agctaatttt tctatttttt gcagagacag 1000

 ggttttgccg tgttgcctag gttgttctca aactcctgag ctcaagcctg 1050

 cctcagcctc ccaaagtgct gggattacat gtgtgagcca ccatgcctgg 1100

 ccgtcactaa tcttcaaggt taatatttgg aggacccatc cagagtccaa 1150

 aggtggtctt cgagggatag cacgaggtgg tctgacagga ctaacactta 1200

 ccagcctcta tgcactatat aataactggg agcacatgaa aggctccttg 1250

 ctccaacagt cactctgaag attttgccaa ctcatgaatg gaggacactt 1300

 cagtagtcat ctagatcctt ttataagaca gtttggagtt attctctctc 1350

 ttctacctac aattagtttg aaaaattgga gattttgatt tgctgtgatg 1400

 aaaatcctgg atggctgacc aagactggca cttgttccag ccattagtga 1450

 gttgaagcca aagccctttg gtgactcact gagtaccatg gttctgttct 1500

 cctctggaga tcttgcacgt atctgttttc ctcccccatg aactagaaaa 1550

 ccacttactc ccagaattca ggtcgtgctt gttagtacta tatcaccaag 1600

 tccattcatt taatgatcca aaactgtaat gttgcactgt attccaaata 1650

 aagggtaaaa acagaaccaa aggtataact ccaaaaaaaa aaaaaaa 1697

<210> 4204
<211> 60
<212> PRT
<213> Homo sapien

<400> 4204
 Met Val Leu Ser Glu Ser Pro Lys Gly Phe Gly Phe Asn Ser Leu
   1               5                  10                  15

 Met Ala Gly Thr Ser Ala Ser Leu Gly Gln Pro Ser Arg Ile Phe
                  20                  25                  30

 Ile Thr Ala Asn Gln Asn Leu Gln Phe Phe Lys Leu Ile Val Gly
                  35                  40                  45

 Arg Arg Glu Arg Ile Thr Pro Asn Cys Leu Ile Lys Gly Ser Arg
                  50                  55                  60

<210> 4205
<211> 3204
<212> DNA
<213> Homo sapien

<400> 4205
 ggcggggctg ggcgcaggca gtctcccgcc gccgccgccg ctgccggacg 50

 cgcagagcga ggggcggctg gaccgacggc tgccgggccg agcgcacaga 100

 gtcgcggcgc agggggcgtc cccggccggg acgcgggtcg cgtcgttgtc 150

 ctccgcgagc gtccggattg caggctgtct gtccccagac cccagagcac 200

 gtccggcacc accatgactg ggctgttgaa gaggaaattt gaccagctgg 250

 atgaggacaa ctcctcggtc tcctcctcct cctcttcctc tgggtgccag 300

 tctcgctcct gctccccaag ctcttctgtc tcccgtgcct gggactcaga 350

 ggaggaaggc ccctgggatc agatgcccct gcctgaccgt gacttctgcg 400

 gccccagaag tttcaccccc ctgtctatcc tgaagcgagc tcgccgggag 450

 cgcccaggcc gtgtagcctt tgatgggatc accgtcttct acttcccccg 500

 ctgccagggc ttcaccagtg tgcccagccg tggtggctgt actctgggta 550

 tggcccttcg ccacagtgct tgccgtcgct tctctttggc tgagtttgcg 600

 caggagcaag cccgtgcacg gcacgagaag ctccgccagc gcttgaaaga 650

 ggagaagttg gagatgctgc agtggaagct ttcggcagct ggggtacccc 700

 aggcagaggc agggctgcca cctgtggtgg atgccattga tgacgcctct 750

 gtggaggagg acttggcagt cgctgtggca ggtggccggt tggaagaagt 800

 gagcttccta cagccctacc cagcccggcg acgtcgagct ctgctgaggg 850

 cttcaggtgt gcgaaggatc gatcgggagg agaagcggga gctgcaggca 900

 ctgcgccaat cccgggagga ttgtggctgt cactgcgata ggatctgcga 950

 ccctgagacc tgcagctgca gcctggcagg catcaagtgc cagatggacc 1000

 acacagcatt cccctgtggc tgctgcaggg agggctgtga gaaccccatg 1050

 ggccgtgtgg aatttaatca ggcaagagtt cagacccatt tcatccacac 1100

 actcacccgc ctgcagttgg aacaggaggc tgagagcttt agggagctgg 1150

 aggcccctgc ccagggcagc ccacccagcc ctggtgagga ggccctggtc 1200

 cctactttcc cactggccaa gccccccatg aacaatgagc tgggagacaa 1250

 cagctgcagc agcgacatga ctgattcttc cacagcatct tcatcagcat 1300

 cgggcactag tgaggctcct gactgcccca cccacccagg cctgcctggc 1350

 cctggcttcc agcctggcgt tgatgatgac agcctggcac gcatcttgag 1400

 tttcagtgac tctgacttcg gtggggagga ggaggaagag gaggaaggga 1450

 gtgtggggaa cctggacaac ctcagctgct tccatccagc tgacatcttt 1500

 ggtactagtg accctggtgg cctggccagc tggacccaca gctattctgg 1550

 ctgtagcttc acatcaggca tcctggatga gaatgccaac ctggatgcca 1600

 gctgcttcct aaatggtggc cttgaagggt caagggaagg cagccttcct 1650

 ggcacctcag tgccacccag catggacgct ggccggagta gctcagtgga 1700

 tctcagcttg tcttcttgtg actcctttga gttactccag gctctgccag 1750

 attatagtct ggggcctcac tacacatcac agaaggtgtc tgacagcctg 1800

 gacaacatcg aggcacctca cttccccctg cctggcctgt ctccacctgg 1850

 ggatgccagc agttgcttcc tggagtccct catgggcttc tccgagccag 1900

 ccgccgaagc cctagatccc tttattgaca gccagtttga ggacactgtc 1950

 ccagcatctc taatggagcc tgtgccggtg tgaggaccag gatgtctttt 2000

 cccagcccca agagacctgt tgctgctttc ttgtaattat ggggctcccc 2050

 agagtctgcg taacagtctc ccactggctg gctcacccac aggtgccatg 2100

 tgcacactcc tggttttcaa acaattctct ggatttattt atttgtttta 2150

 acttttctgt gctgaagaga ggactagggg gagggggctt cccctttcag 2200

 ctgcccggcc ccccacaccc acagcttgct cttctatctc cacaacgtga 2250

 gcctggaaga ggagaaaatg tggctcctct ggagcttggc agaccacttt 2300

 tcggtctttg cgtgatgttc cttagcccaa agacggtgag acagggctga 2350

 aatcaggtgg cttctgccac cctgagccct agacccatgg gtggctaaat 2400

 ccactggact gtgaagacta taatttattt ccataattta tttggagatt 2450

 gaggaggctt tggttgcact tctttggctg gtgggtaatg ccaggggtgg 2500

 ggtgggcaca ggccctcaag agcccctttt gccttgtagt cctacacctt 2550

 gccctgcctg ggctttggtg cagactaggt gtggatttga gctctgtgat 2600

 ctatgtctgc tgcctggctc ctagatggct ctgcgggcag gtgctggcca 2650

 aggacatcat ctaggcaggg ggagagcctg ggctgaacag ctgtgaccaa 2700

 aactcccttc tgccccaccc tgccccctcc acttcctgcc ctctgttcca 2750

 tcttccccct tcccaaaggc cacagccttt attccaggcc cagggatgta 2800

 ggagggggaa ggaggaaaca ggaagcccag agagggcaaa gggcctacct 2850

 cggggcgcga accatgcccc agactattat ctcagggctt tctgggcact 2900

 gcacttcagc gtggcccacc tgcccatgcc ctgaggccag ttggcgaggg 2950

 gtggctcctg agggttttta taccctttgt ttgctaatgt ttaattttgc 3000

 atcataattt ctacattgtc cctgagtgtc agaactataa tttattccat 3050

 ttctctctgt gtctgtgcca agaaacgcag gctctgggcc tgccccttgc 3100

 ccaggaggcc ttgccagcct gtgtgcttgt gggaacacct tgtacctgag 3150

 cttacaggta ccaataaaga ggctttattt ttaaaaaaaa aaaaaaaaaa 3200

 aaaa 3204

<210> 4206
<211> 589
<212> PRT
<213> Homo sapien

<400> 4206
 Met Thr Gly Leu Leu Lys Arg Lys Phe Asp Gln Leu Asp Glu Asp
   1               5                  10                  15

 Asn Ser Ser Val Ser Ser Ser Ser Ser Ser Ser Gly Cys Gln Ser
                  20                  25                  30

 Arg Ser Cys Ser Pro Ser Ser Ser Val Ser Arg Ala Trp Asp Ser
                  35                  40                  45

 Glu Glu Glu Gly Pro Trp Asp Gln Met Pro Leu Pro Asp Arg Asp
                  50                  55                  60

 Phe Cys Gly Pro Arg Ser Phe Thr Pro Leu Ser Ile Leu Lys Arg
                  65                  70                  75

 Ala Arg Arg Glu Arg Pro Gly Arg Val Ala Phe Asp Gly Ile Thr
                  80                  85                  90

 Val Phe Tyr Phe Pro Arg Cys Gln Gly Phe Thr Ser Val Pro Ser
                  95                 100                 105

 Arg Gly Gly Cys Thr Leu Gly Met Ala Leu Arg His Ser Ala Cys
                 110                 115                 120

 Arg Arg Phe Ser Leu Ala Glu Phe Ala Gln Glu Gln Ala Arg Ala
                 125                 130                 135

 Arg His Glu Lys Leu Arg Gln Arg Leu Lys Glu Glu Lys Leu Glu
                 140                 145                 150

 Met Leu Gln Trp Lys Leu Ser Ala Ala Gly Val Pro Gln Ala Glu
                 155                 160                 165

 Ala Gly Leu Pro Pro Val Val Asp Ala Ile Asp Asp Ala Ser Val
                 170                 175                 180

 Glu Glu Asp Leu Ala Val Ala Val Ala Gly Gly Arg Leu Glu Glu
                 185                 190                 195

 Val Ser Phe Leu Gln Pro Tyr Pro Ala Arg Arg Arg Arg Ala Leu
                 200                 205                 210

 Leu Arg Ala Ser Gly Val Arg Arg Ile Asp Arg Glu Glu Lys Arg
                 215                 220                 225

 Glu Leu Gln Ala Leu Arg Gln Ser Arg Glu Asp Cys Gly Cys His
                 230                 235                 240

 Cys Asp Arg Ile Cys Asp Pro Glu Thr Cys Ser Cys Ser Leu Ala
                 245                 250                 255

 Gly Ile Lys Cys Gln Met Asp His Thr Ala Phe Pro Cys Gly Cys
                 260                 265                 270

 Cys Arg Glu Gly Cys Glu Asn Pro Met Gly Arg Val Glu Phe Asn
                 275                 280                 285

 Gln Ala Arg Val Gln Thr His Phe Ile His Thr Leu Thr Arg Leu
                 290                 295                 300

 Gln Leu Glu Gln Glu Ala Glu Ser Phe Arg Glu Leu Glu Ala Pro
                 305                 310                 315

 Ala Gln Gly Ser Pro Pro Ser Pro Gly Glu Glu Ala Leu Val Pro
                 320                 325                 330

 Thr Phe Pro Leu Ala Lys Pro Pro Met Asn Asn Glu Leu Gly Asp
                 335                 340                 345

 Asn Ser Cys Ser Ser Asp Met Thr Asp Ser Ser Thr Ala Ser Ser
                 350                 355                 360

 Ser Ala Ser Gly Thr Ser Glu Ala Pro Asp Cys Pro Thr His Pro
                 365                 370                 375

 Gly Leu Pro Gly Pro Gly Phe Gln Pro Gly Val Asp Asp Asp Ser
                 380                 385                 390

 Leu Ala Arg Ile Leu Ser Phe Ser Asp Ser Asp Phe Gly Gly Glu
                 395                 400                 405

 Glu Glu Glu Glu Glu Glu Gly Ser Val Gly Asn Leu Asp Asn Leu
                 410                 415                 420

 Ser Cys Phe His Pro Ala Asp Ile Phe Gly Thr Ser Asp Pro Gly
                 425                 430                 435

 Gly Leu Ala Ser Trp Thr His Ser Tyr Ser Gly Cys Ser Phe Thr
                 440                 445                 450

 Ser Gly Ile Leu Asp Glu Asn Ala Asn Leu Asp Ala Ser Cys Phe
                 455                 460                 465

 Leu Asn Gly Gly Leu Glu Gly Ser Arg Glu Gly Ser Leu Pro Gly
                 470                 475                 480

 Thr Ser Val Pro Pro Ser Met Asp Ala Gly Arg Ser Ser Ser Val
                 485                 490                 495

 Asp Leu Ser Leu Ser Ser Cys Asp Ser Phe Glu Leu Leu Gln Ala
                 500                 505                 510

 Leu Pro Asp Tyr Ser Leu Gly Pro His Tyr Thr Ser Gln Lys Val
                 515                 520                 525

 Ser Asp Ser Leu Asp Asn Ile Glu Ala Pro His Phe Pro Leu Pro
                 530                 535                 540

 Gly Leu Ser Pro Pro Gly Asp Ala Ser Ser Cys Phe Leu Glu Ser
                 545                 550                 555

 Leu Met Gly Phe Ser Glu Pro Ala Ala Glu Ala Leu Asp Pro Phe
                 560                 565                 570

 Ile Asp Ser Gln Phe Glu Asp Thr Val Pro Ala Ser Leu Met Glu
                 575                 580                 585

 Pro Val Pro Val


<210> 4207
<211> 5141
<212> DNA
<213> Homo sapien

<400> 4207
 gaagcgccgc cgccaccgcc gcctttgctg tcccccggcc tctagttccc 50

 cgcaggtggg aggtgggagc catgtcgaaa cggctccgga gcagcgaggt 100

 gtgcgctgac tgcagcgggc cggatccttc ctgggcatca gtaaataggg 150

 gaacgttttt atgtgatgag tgctgcagtg tccatcggag tctagggcgc 200

 catatctccc aagtgaggca tctgaaacac acaccgtggc ctccaacact 250

 gcttcagatg gttgagacct tgtataataa cggtgctaac tctatatggg 300

 agcattcttt gctggaccct gcgtctatta tgagtggaag acgtaaagct 350

 aatccacagg ataaagtaca tcccaataaa gcggaattca tcagagccaa 400

 gtatcagatg ttagcgttcg tccatcgctt gccctgccgg gatgacgata 450

 gtgtgactgc caaagatctt agcaagcaac tccattcgag cgtgagaaca 500

 gggaatcttg aaacctgttt gagactgtta tctttaggag cacaagccaa 550

 cttctttcat cctgaaaaag gaaacacccc actccatgtt gcctccaaag 600

 cagggcagat tttacaggct gaattattgg cagtatatgg agcagaccca 650

 ggcacacagg attctagtgg gaaaactccc gttgattatg caaggcaagg 700

 agggcaccat gagctggcag agcgcctcgt ggaaatacag tatgagctaa 750

 cggacagact agccttctat ctctgtggca ggaaaccaga tcacaaaaat 800

 ggacagcact ttataatacc tcaaatggca gacagcagcc tggatttgtc 850

 tgaattggca aaagctgcta agaagaaact tcaatctcta agtaatcatt 900

 tgtttgaaga acttgccatg gatgtgtacg atgaagttga caggcgagag 950

 acggatgcag tctggcttgc cacgcaaaac cacagcgccc tggtaaccga 1000

 gacaacggtc gtcccctttc ttccggtcaa tcctgagtac tcatcaacac 1050

 gaaatcaggg cagacagaag ttagctcggt tcaacgccca tgagtttgcc 1100

 acgctggtca ttgacattct cagtgacgcc aagaggagac agcagggcag 1150

 ttctctctcg ggttcaaaag acaatgtgga gctcatactg aaaaccatca 1200

 ataaccagca cagcgttgag agtcaagaca acgatcagcc cgactatgac 1250

 agcgtggcat cagacgaaga cacagatttg gaaaccactg caagcaaaac 1300

 aaaccggcag aagagcctag attcagattt atcagatgga ccagtcactg 1350

 tacaggaatt tatggaggtc aaaaacgctc tagtggcttc tgaggccaag 1400

 atacagcagc taatgaaggc atccaggctg gagaagcaga acagcacacc 1450

 tgagagtgac tacgacaaca ctcccaacga catggagcca gatggcatgg 1500

 ggtcaagccg aaagggacgg caaagaagta tggtgtggcc aggggatggc 1550

 ttggtaccag acacagcaga accccatgtg gccccaagcc ccactctccc 1600

 tagcaccgaa gatgtcatca ggaagactga acagatcacc aaaaacatac 1650

 aggagctctt aagagcagcc caagaaaata aacatgacag ttatattccc 1700

 tgctcagaga ggatacacgt agctgttaca gaaatggcag cattattccc 1750

 caaaaaaccc aagtctgata tggtgaggac ttcccttcgt ttactgacgt 1800

 ccagtgccta ccgactgcag tcagagtgca agaagaccct cccaggggac 1850

 cccggctcac ccacagacgt tcagctggtc acgcagcagg tcatccagtg 1900

 tgcgtacgac atcgccaagg ctgccaagca gctggttacc atcaccacca 1950

 aagagaacaa caactgacaa gggcagggca ccgcctcctc tgttttctag 2000

 gctttataaa gtccaatttc aaattcagac gcagaactct tcagatttct 2050

 acaaaaagaa acatttaatg acggtttaaa actttttaaa agaaaactca 2100

 gtattatttt tgcatgtttt ctaaccaatt ttcaactatt taacccactt 2150

 gccttatttt gtgcctattt gctggtttag tttctgatgt tcggttgtgt 2200

 tgtcaacaac tgttgagttg atcacataca tccaaaagta tagtttcatt 2250

 gtctaaagtt tgtgaaaact tttccatccc ttaaaactcc ctgcctatgg 2300

 ctgaaactat aaatgaaatt tttcataaaa cattttcttg agagagttca 2350

 gttaaaaaag aaaaaatcag cgtcatttgt tccctgccaa gcatcgtgca 2400

 ataagtgaat ttcctggcct acttcataat ctctaagttt ggggtatctc 2450

 caagcatgta tgtagagaaa ggactttgcc gctttttaaa actagtgtca 2500

 cagtctctct tgggaggaaa caatgaattg gttcatttct tctcagtgtt 2550

 ttaccctgtt acatgttctg ttatttaatg ttgttatctc aagctcctat 2600

 ctcttgatgt tttcttgtca tcttgaaggc tccatggaat gagataaagc 2650

 attgacccac cacaggacat ctcatgaagc catgttcagg gtaggagctc 2700

 cacgcacatc accacccatt gtcaggtgct ctccctcacc cctgtaagcc 2750

 agacagtttg ttcaaaacct gcagcaaaga gaagcatcag tctaacaagc 2800

 cagaactcat tttgtgccac ccatttaggt atcactacca tgaactatag 2850

 ggaaaagaaa tcacctactc cctgacactg tgttgtaccc ttcatccaaa 2900

 agtcagcttg cttctctgac cacttacagc tttctcacat gagttgcttc 2950

 acatttttca tcatctttaa ggacttctta taaggaaaga tgtatcgtat 3000

 cgcagtcatc tgagttagtt tctcctccat cacctcatga gtacttaaaa 3050

 attagacatc aactttcaag agttccttag agagtgtgct ctagctggct 3100

 gcctgctacc ccaaagctct gaaagagtaa ggttgaagtg ctggaacatg 3150

 ctcagattgt tttttagtta ctcaaaagcc ccttcttgtt ctgaatgtga 3200

 aagctcttcc cgttcctgct tactgcagcc attctgtgtg tgtggttcag 3250

 accctggcct agggccggtg atgtggatga gtgaagggag ccaggtacac 3300

 ggcagcaggg cagaggagac tatggggagc ccaccgccta cacagtaggg 3350

 gcagtagccc ccagctccac gcctgttgcc atgtggaaaa gtgggcctag 3400

 ggtggccaca gctttgattt ttcaagagac aagaaaccta gatgtttttt 3450

 ggtgccatct ctccatttat aaatgttggc aaccaatttg aacactttca 3500

 gagaccatgt gcaggtgagc tgtgtcctct aggctgccag ctcacagccc 3550

 ccaccccagg gccctgtaag ctgtgcagtg tgagggcctg gcttccccgg 3600

 acacacctgg agcagcctct gagtcttacc cgtaatggag ccggccaacc 3650

 ctgtgtgtta tgttgctgtc gctcctgttt ttaaccatat gttctgtccc 3700

 atagcagtca ttcacacatg tgaagaagac acaagaatca aagtacaagt 3750

 tgcctcaata catgctaata actaagcttc tattttcaca ggactgatcg 3800

 atgcacacct ttatagcttg accatatgct gtcatgaaag tagcaccccg 3850

 acggtgcttg ctttactaag tcaccgtgtg tggatgcttt tgtcgcattt 3900

 tgcttcactg tgagtagcat gggaaaaggg tccacgtctc caaaagactc 3950

 ttccacttgt ttgtcccaca gccctaagtg ccacattgct gttggatgct 4000

 cccgggatgc cttctagaag ggggcctccc accttaagtt caggcgccat 4050

 ctgatagcct tttctgcagg cttcatgtcc ttagctgacc ctcctttatc 4100

 ttgcaaaccc ctgcccctgc tgtcccaggg aggacgggct tctgtagagg 4150

 cttctgggaa atgagctgtc tgcaggaggt gaagcagtgt tttccttgga 4200

 atgtttgagg acctgcaata gaagatgttg cctttatggc cctagagaaa 4250

 gtcaaggaac atggggacca acaaagcatt tccagttgta agaatatgtc 4300

 agaagagtgc tcggttagcc cacggtgcca aaactccaaa caagttcccc 4350

 ggtggaatga cgtggccatt ggagggctgc aggtcgtcct ctctgtatgt 4400

 gccccgcgca tttccttggc ctcatctgag atctggtgtc agagttctct 4450

 gctcctgttg gcaaatcgca ccttatctga acatttgttc cagccacctt 4500

 ttgcacatgg attccgtacc ttgcactagc aatgtctacc ttcagtaacg 4550

 tcgttctttt tcaccctgta ttctcaatga tcccttcctc cccatatgcc 4600

 acccttcccc caaagctgat agggcagagg tgcactttat gaaactggca 4650

 cttgactgaa cagaaggaaa cagctgtacc tctaagctcc tttcacagaa 4700

 atcgtcatct gccttggaat gcaaatagtt cttatttgcc aaagaacagt 4750

 gaattgggcc caaagatcaa acacagcatt tcatgtaatc agaattctaa 4800

 acgcacaact cgggagctgt gcacggcttc tcaagtgatt cagttgcaga 4850

 accaagagca aaactcgcct gtttttgtcc tcaatggcac ccatgagctt 4900

 tccaatagta tagttttctt tctttccttg tcctggttga aggtaacgtg 4950

 ttcctagaaa agaaaatgct gcataggaaa actgagatgc cttttattcc 5000

 aacgtgtttg atccctgtca ctcattattc tgtacttttt attgtacatt 5050

 ctattcctgt aattattgtg ccctttaagt gttgtaaaat cgttttggaa 5100

 tttgtgcctg ctagttatgc aataaacagg ctctacaagt g 5141

<210> 4208
<211> 631
<212> PRT
<213> Homo sapien

<400> 4208
 Met Ser Lys Arg Leu Arg Ser Ser Glu Val Cys Ala Asp Cys Ser
   1               5                  10                  15

 Gly Pro Asp Pro Ser Trp Ala Ser Val Asn Arg Gly Thr Phe Leu
                  20                  25                  30

 Cys Asp Glu Cys Cys Ser Val His Arg Ser Leu Gly Arg His Ile
                  35                  40                  45

 Ser Gln Val Arg His Leu Lys His Thr Pro Trp Pro Pro Thr Leu
                  50                  55                  60

 Leu Gln Met Val Glu Thr Leu Tyr Asn Asn Gly Ala Asn Ser Ile
                  65                  70                  75

 Trp Glu His Ser Leu Leu Asp Pro Ala Ser Ile Met Ser Gly Arg
                  80                  85                  90

 Arg Lys Ala Asn Pro Gln Asp Lys Val His Pro Asn Lys Ala Glu
                  95                 100                 105

 Phe Ile Arg Ala Lys Tyr Gln Met Leu Ala Phe Val His Arg Leu
                 110                 115                 120

 Pro Cys Arg Asp Asp Asp Ser Val Thr Ala Lys Asp Leu Ser Lys
                 125                 130                 135

 Gln Leu His Ser Ser Val Arg Thr Gly Asn Leu Glu Thr Cys Leu
                 140                 145                 150

 Arg Leu Leu Ser Leu Gly Ala Gln Ala Asn Phe Phe His Pro Glu
                 155                 160                 165

 Lys Gly Asn Thr Pro Leu His Val Ala Ser Lys Ala Gly Gln Ile
                 170                 175                 180

 Leu Gln Ala Glu Leu Leu Ala Val Tyr Gly Ala Asp Pro Gly Thr
                 185                 190                 195

 Gln Asp Ser Ser Gly Lys Thr Pro Val Asp Tyr Ala Arg Gln Gly
                 200                 205                 210

 Gly His His Glu Leu Ala Glu Arg Leu Val Glu Ile Gln Tyr Glu
                 215                 220                 225

 Leu Thr Asp Arg Leu Ala Phe Tyr Leu Cys Gly Arg Lys Pro Asp
                 230                 235                 240

 His Lys Asn Gly Gln His Phe Ile Ile Pro Gln Met Ala Asp Ser
                 245                 250                 255

 Ser Leu Asp Leu Ser Glu Leu Ala Lys Ala Ala Lys Lys Lys Leu
                 260                 265                 270

 Gln Ser Leu Ser Asn His Leu Phe Glu Glu Leu Ala Met Asp Val
                 275                 280                 285

 Tyr Asp Glu Val Asp Arg Arg Glu Thr Asp Ala Val Trp Leu Ala
                 290                 295                 300

 Thr Gln Asn His Ser Ala Leu Val Thr Glu Thr Thr Val Val Pro
                 305                 310                 315

 Phe Leu Pro Val Asn Pro Glu Tyr Ser Ser Thr Arg Asn Gln Gly
                 320                 325                 330

 Arg Gln Lys Leu Ala Arg Phe Asn Ala His Glu Phe Ala Thr Leu
                 335                 340                 345

 Val Ile Asp Ile Leu Ser Asp Ala Lys Arg Arg Gln Gln Gly Ser
                 350                 355                 360

 Ser Leu Ser Gly Ser Lys Asp Asn Val Glu Leu Ile Leu Lys Thr
                 365                 370                 375

 Ile Asn Asn Gln His Ser Val Glu Ser Gln Asp Asn Asp Gln Pro
                 380                 385                 390

 Asp Tyr Asp Ser Val Ala Ser Asp Glu Asp Thr Asp Leu Glu Thr
                 395                 400                 405

 Thr Ala Ser Lys Thr Asn Arg Gln Lys Ser Leu Asp Ser Asp Leu
                 410                 415                 420

 Ser Asp Gly Pro Val Thr Val Gln Glu Phe Met Glu Val Lys Asn
                 425                 430                 435

 Ala Leu Val Ala Ser Glu Ala Lys Ile Gln Gln Leu Met Lys Ala
                 440                 445                 450

 Ser Arg Leu Glu Lys Gln Asn Ser Thr Pro Glu Ser Asp Tyr Asp
                 455                 460                 465

 Asn Thr Pro Asn Asp Met Glu Pro Asp Gly Met Gly Ser Ser Arg
                 470                 475                 480

 Lys Gly Arg Gln Arg Ser Met Val Trp Pro Gly Asp Gly Leu Val
                 485                 490                 495

 Pro Asp Thr Ala Glu Pro His Val Ala Pro Ser Pro Thr Leu Pro
                 500                 505                 510

 Ser Thr Glu Asp Val Ile Arg Lys Thr Glu Gln Ile Thr Lys Asn
                 515                 520                 525

 Ile Gln Glu Leu Leu Arg Ala Ala Gln Glu Asn Lys His Asp Ser
                 530                 535                 540

 Tyr Ile Pro Cys Ser Glu Arg Ile His Val Ala Val Thr Glu Met
                 545                 550                 555

 Ala Ala Leu Phe Pro Lys Lys Pro Lys Ser Asp Met Val Arg Thr
                 560                 565                 570

 Ser Leu Arg Leu Leu Thr Ser Ser Ala Tyr Arg Leu Gln Ser Glu
                 575                 580                 585

 Cys Lys Lys Thr Leu Pro Gly Asp Pro Gly Ser Pro Thr Asp Val
                 590                 595                 600

 Gln Leu Val Thr Gln Gln Val Ile Gln Cys Ala Tyr Asp Ile Ala
                 605                 610                 615

 Lys Ala Ala Lys Gln Leu Val Thr Ile Thr Thr Lys Glu Asn Asn
                 620                 625                 630

 Asn


<210> 4209
<211> 4868
<212> DNA
<213> Homo sapien

<400> 4209
 cgtggaagcg gagcggcggc ctcgctgtaa cgcagaagcg aaatgtagcg 50

 agccgggtgt cgcggctgga cgctcgcctt ggctgggggt gtgggggggc 100

 acgccggggg ccaaggagga ctgtcgagga ggagtgatga gaagaggggg 150

 tgccctgcac cccccgagac cacgggccac gctgccactt gccaggcgcc 200

 ccccttcctc ccaggcgagg ggcaggtgtt ccacactgat tctcgtgact 250

 ttaaggacca gggatttgaa gaggtattag ctcttcccag gaagggagga 300

 agtttctgga agagaaggga aagacggcag acgctgcgct gggaccagca 350

 gagcctgagg agctgtggga agctgacaga gcccagccaa aggagcggga 400

 aggagccgca gccccaggct ggcactgtgt tctgaaagat ttgaactcaa 450

 gctgcttttt acggaagagg ggccacttca gagggcaccc cagaatttgg 500

 ttgagctctt ctactctgga tgccccctgc tctgaggagc ctgccactga 550

 gaaccaaaga agataagagg acagatactt tttcttcaag cacagagctg 600

 gtgggttgga gtcaggcatc tgcaccccta gtggctgtct ggtgaggaat 650

 ttcttgtttc ttcccagctt gcggcttcag tgcttgatgg ggctgcctgt 700

 tggtggatca gtttttgcag cgcctggtag gagtggagag ccgtgggaag 750

 aggtcctgcg gcgcccaagc ctgggttcac cccaagacta agttctttcc 800

 caagttagag aagaagagag aaagcaaaaa gaagagagga aagttctccc 850

 ttcccctcct ccgtgcctgt catgtcctct aagccagagc cgaaggacgt 900

 ccaccaactg aacgggactg gcccttctgc ctctccctgc tcttcagatg 950

 gcccagggag agagcccttg gctgggacct cagagttcct ggggcctgat 1000

 ggggctgggg tagaggtggt gattgagtct cgggccaacg ccaagggggt 1050

 tcgggaggag gacgccctgc tggagaacgg gagccagagc aacgaaagtg 1100

 acgacgtcag cacagaccgt ggccctgcgc caccttcccc gctcaaggag 1150

 acctcctttt ccatcgggct gcaagtactg tttccattcc tcctggcagg 1200

 ctttgggact gtggctgctg gcatggtgtt ggacatcgtg cagcactggg 1250

 aagtcttcca gaaggtgaca gaggtcttca tcctagtgcc tgcgctgctg 1300

 gggctcaaag ggaacctgga aatgaccctg gcatcaaggc tttccactgc 1350

 agccaacatt ggacacatgg acacacccaa ggagctctgg cggatgatca 1400

 ctgggaacat ggccctcatc caggtgcagg ccacggtggt gggcttcctg 1450

 gcgtccaccg cagccgtcgt ctttggctgg gtccctgatg gccacttcag 1500

 tattccgcac gccttcctgc tctgtgctag cagcgtggcc acagccttca 1550

 ttgcctccct ggtactgggt atgatcatga ttggagtcat cattggctct 1600

 cgcaagattg ggatcaaccc agacaacgtg gccacaccca ttgctgccag 1650

 cctgggcgac ctcatcacct tggcgctgct ctcaggcatc agctggggac 1700

 tctacctgga actgaatcac tggcggtaca tctacccact ggtgtgtgct 1750

 ttctttgtgg ccctgctgcc tgtctgggtg gtgctggccc gacgaagtcc 1800

 agccacaagg gaggtgttgt actcgggctg ggagcctgtt atcattgcca 1850

 tggccatcag cagtgtggga ggcctcatct tggacaagac tgtctcagac 1900

 cccaactttg ctgggatggc tgtcttcacg cctgtgatta atggtgttgg 1950

 gggcaatctg gtggcagtgc aggccagccg catctccacc ttcctgcaca 2000

 tgaatggaat gcccggagag aactctgagc aagctcctcg ccgctgtccc 2050

 agtccttgta ccaccttctt cagccctgat gtgaattctc gctcagcccg 2100

 ggtcctcttc ctcctcgtgg tcccaggaca cctggtgttc ctctacacca 2150

 tcagctgtat gcagggcggg cacaccaccc tcacactcat cttcatcatc 2200

 ttctatatga cagctgcact gctccaggtg ctgattctcc tgtacatcgc 2250

 agactggatg gtgcactgga tgtggggccg gggcctggac ccggacaact 2300

 tctccatccc atacttgact gctctggggg acctgcttgg cactgggctc 2350

 ctagcactca gcttccatgt tctctggctc ataggggacc gagacacgga 2400

 tgtcggggac tagcttggtc actcaacatt ttccccatcc ctctgcactt 2450

 tctatttgaa atttttcttt tgttcccctg tccctcctcc accccacact 2500

 cccacctctt tctaggactt cactttgata ccaaattctc attattttca 2550

 atgggaattt ttatacattg agccaagttt gtatagcaag aatttgggaa 2600

 acacagatgg cctgagataa gcagtacaag taggtttttg agacaatcac 2650

 caagtgcagt ttcatggtgg gtgcctccag gtgatgtgga ctggagcagg 2700

 ggagttttgt ctggaatctg gggacatggg gtttggcttt agcaacctgt 2750

 cttggcccta atgagaaacc ctttgtaagt gggctctgga tttttggttt 2800

 tgttttcttt ttatctgttt tgttttattt ttggttttgg ttgaacagag 2850

 ggacagaaga ataagtaaca ctcccaaaca cagacatact tttgtagaag 2900

 tggaccaact tcaaagctct ggacaggaga cacctgctcc aggcccctgt 2950

 gatcccagtt ctgttctctt gccctctgga cctaagcgtt cccactcgca 3000

 gaaagagtaa ggtggactga cttttcaatt tgtgcacatg cctcttgttc 3050

 aatggcctgg tcaacatcaa caacccctcc ctctgatcat ttccagttga 3100

 ttgtcatatc caggaaaaaa tggaacagtg cactcttctc cctgttgacc 3150

 catgtccacc tattggttcc ccaaaatcca cattctccct gggcccagat 3200

 gactttgtct ccctgggccc agattctttg tctctcttca accttcatct 3250

 caaattgtct ctaagcacta ccttccccag agcttgccag gttgggtttt 3300

 gagattaggg tcaggtcatg ggtatgtgga gaatggtttg gaggttgagg 3350

 acaaccacag gtgtctcatt gctgccattt ctcctgagga cataatcact 3400

 tggtcacctt ggaccctgtc acttcctaaa attactcgtt ctgtcatgcc 3450

 atagaggtca gttttcctct ttcttggctt ctacccacaa acattcacca 3500

 atcatttatt cgttcattta gcaaatatgc agcctccgca agatgagctc 3550

 tcctgcagac aagcatggtc tgaaacattc tttgagcaat atttattgag 3600

 tgcctactat gtgttaggta ctgtgccagg cactgataag ccagtggtaa 3650

 gggaaacaca gctctaacct cacctcattc tccaggttac aaaggccatg 3700

 tgcccctttg aatctggcag agaaagtttc ctcgttgtaa gtatttgcat 3750

 ctacttcaag ccagattctt ctgcctcttt ctcctttcca gacccctact 3800

 ctgtgcagtg ctgaccacag ctagagccac cgccccattg ctcaaccagt 3850

 atttatttcc ctaaacgacc cttcctcaca ttcccttccc tccacctctc 3900

 cttaccaagc acccaaaaga ggatttagaa ctagcagggt ggacatcatc 3950

 tggttgtttc tacttttctc tgcctagcac aaaattggga gaaaactgga 4000

 gcctccatcc gcagtcacac gtgtacagat ctggggattt ggatgtaggc 4050

 tttttctaac ttctctctca gaagcttcta cagaaaccct tccatctgta 4100

 gcctcaaggg cccacctcca agggaaggct taggcaatga tcctgtttct 4150

 accaacactg caccttatcc caggaacctg ccctagacct ccagagacca 4200

 tattttctct ccctccattt ctacccagac ctccaggcct ccttctggaa 4250

 tcatagaacc atagaattgg aaggaatttt agaggttttc tagttggagt 4300

 tgtgtccaac agaattcatt aacaccagcc tgggcttgtt tttcctcctc 4350

 cctctggact tttttcatct tttcctccac ctcaaaaaat acttacacac 4400

 agattcttct tgtacaggca tcaaaaccaa ctcctctgcc cctaaggctg 4450

 tgtccctgtg gtctccagcc acccctaccc cagtcactcg ccccttcctc 4500

 atctctggaa tttggccagg cagtcccaga agactctgga gtgacctcct 4550

 ttgcctaaaa agcagacaga taggcatgcc ccaggccctg agtgagcaga 4600

 ggaggactgt agggtgagag ggaaagaaaa tgaaggtgac tttcatggaa 4650

 gtttcatttc ttttccccga ttgtaccaac tgcatgtact tttggcctgg 4700

 ctgcaaggag caatattggt ttactctcgt atccttaaaa agttacagaa 4750

 ctgtgtctta agagaattat ttatagttac tataactgaa ttgacaaatg 4800

 tcaacttaac tgataaatta tatttggtaa aataaagagg acgtttattc 4850

 aaaaaaaaaa aaaaaaaa 4868

<210> 4210
<211> 513
<212> PRT
<213> Homo sapien

<400> 4210
 Met Ser Ser Lys Pro Glu Pro Lys Asp Val His Gln Leu Asn Gly
   1               5                  10                  15

 Thr Gly Pro Ser Ala Ser Pro Cys Ser Ser Asp Gly Pro Gly Arg
                  20                  25                  30

 Glu Pro Leu Ala Gly Thr Ser Glu Phe Leu Gly Pro Asp Gly Ala
                  35                  40                  45

 Gly Val Glu Val Val Ile Glu Ser Arg Ala Asn Ala Lys Gly Val
                  50                  55                  60

 Arg Glu Glu Asp Ala Leu Leu Glu Asn Gly Ser Gln Ser Asn Glu
                  65                  70                  75

 Ser Asp Asp Val Ser Thr Asp Arg Gly Pro Ala Pro Pro Ser Pro
                  80                  85                  90

 Leu Lys Glu Thr Ser Phe Ser Ile Gly Leu Gln Val Leu Phe Pro
                  95                 100                 105

 Phe Leu Leu Ala Gly Phe Gly Thr Val Ala Ala Gly Met Val Leu
                 110                 115                 120

 Asp Ile Val Gln His Trp Glu Val Phe Gln Lys Val Thr Glu Val
                 125                 130                 135

 Phe Ile Leu Val Pro Ala Leu Leu Gly Leu Lys Gly Asn Leu Glu
                 140                 145                 150

 Met Thr Leu Ala Ser Arg Leu Ser Thr Ala Ala Asn Ile Gly His
                 155                 160                 165

 Met Asp Thr Pro Lys Glu Leu Trp Arg Met Ile Thr Gly Asn Met
                 170                 175                 180

 Ala Leu Ile Gln Val Gln Ala Thr Val Val Gly Phe Leu Ala Ser
                 185                 190                 195

 Thr Ala Ala Val Val Phe Gly Trp Val Pro Asp Gly His Phe Ser
                 200                 205                 210

 Ile Pro His Ala Phe Leu Leu Cys Ala Ser Ser Val Ala Thr Ala
                 215                 220                 225

 Phe Ile Ala Ser Leu Val Leu Gly Met Ile Met Ile Gly Val Ile
                 230                 235                 240

 Ile Gly Ser Arg Lys Ile Gly Ile Asn Pro Asp Asn Val Ala Thr
                 245                 250                 255

 Pro Ile Ala Ala Ser Leu Gly Asp Leu Ile Thr Leu Ala Leu Leu
                 260                 265                 270

 Ser Gly Ile Ser Trp Gly Leu Tyr Leu Glu Leu Asn His Trp Arg
                 275                 280                 285

 Tyr Ile Tyr Pro Leu Val Cys Ala Phe Phe Val Ala Leu Leu Pro
                 290                 295                 300

 Val Trp Val Val Leu Ala Arg Arg Ser Pro Ala Thr Arg Glu Val
                 305                 310                 315

 Leu Tyr Ser Gly Trp Glu Pro Val Ile Ile Ala Met Ala Ile Ser
                 320                 325                 330

 Ser Val Gly Gly Leu Ile Leu Asp Lys Thr Val Ser Asp Pro Asn
                 335                 340                 345

 Phe Ala Gly Met Ala Val Phe Thr Pro Val Ile Asn Gly Val Gly
                 350                 355                 360

 Gly Asn Leu Val Ala Val Gln Ala Ser Arg Ile Ser Thr Phe Leu
                 365                 370                 375

 His Met Asn Gly Met Pro Gly Glu Asn Ser Glu Gln Ala Pro Arg
                 380                 385                 390

 Arg Cys Pro Ser Pro Cys Thr Thr Phe Phe Ser Pro Asp Val Asn
                 395                 400                 405

 Ser Arg Ser Ala Arg Val Leu Phe Leu Leu Val Val Pro Gly His
                 410                 415                 420

 Leu Val Phe Leu Tyr Thr Ile Ser Cys Met Gln Gly Gly His Thr
                 425                 430                 435

 Thr Leu Thr Leu Ile Phe Ile Ile Phe Tyr Met Thr Ala Ala Leu
                 440                 445                 450

 Leu Gln Val Leu Ile Leu Leu Tyr Ile Ala Asp Trp Met Val His
                 455                 460                 465

 Trp Met Trp Gly Arg Gly Leu Asp Pro Asp Asn Phe Ser Ile Pro
                 470                 475                 480

 Tyr Leu Thr Ala Leu Gly Asp Leu Leu Gly Thr Gly Leu Leu Ala
                 485                 490                 495

 Leu Ser Phe His Val Leu Trp Leu Ile Gly Asp Arg Asp Thr Asp
                 500                 505                 510

 Val Gly Asp


<210> 4211
<211> 4642
<212> DNA
<213> Homo sapien

<400> 4211
 atggcaaagc aaccttctga tgtaagttct gagtgtgacc gagaaggtag 50

 acaattgcag cctgcggaga ggcctcccca gctcagacct ggggccccta 100

 cctccctaca gacagagcca caagacagga gcccagcacc catgagttgt 150

 gacaaatcaa cacaaacccc aagtcctcct tgccaggcct tcaaccacta 200

 tctcagtgca atggcttcca tgaggcaggc tgaacctgca gatatgcgcc 250

 cagagatatg gatcgcccaa gagttgcggc gtattggaga cgagtttaac 300

 gcttactatg caaggagggt atttttgaat aattaccaag cagccgaaga 350

 ccacccacga atggttatct tacgactgtt acgttacatt gtccgcctgg 400

 tgtggagaat gcattgacag gttctttgcg gagccgagat accatgcaga 450

 cattttgctt gttcaaacca acaagaccca gcaccgcggt ctcctggtgc 500

 cattattatg cagccagcgg ttctcttgtg gagggggcag gtgacgtttc 550

 agaagacacc gagctggatg ggactacctt tctgttcatc accacacagc 600

 agaatttcta atggaagttt gttgtgaatg taaaggaggg agcattcttt 650

 gctttttaat atacaaacca tggttttttg gagcaggatt ttgtgtaaga 700

 atggtgttta catgcagtgt gttttccccc tcaccttcaa taaggttttt 750

 caaaaaggaa atggaaactt tttaaccaat ttgtgaataa cttttgtatt 800

 aaaattttaa gaacctacgg cctattctca gaggattatg taacccctgc 850

 agtggaaact gagccagcta acttaaaaag ctgccttagt ttatttttag 900

 agattacaga atttttaaac agggagacgt gtgatatact ccctcccttc 950

 cctactattg cctctctgac ctttttaaat tatttttaat accaaaagag 1000

 ttcttttgaa atggaactga ttaaaagggc agagggtctg ttgccagcct 1050

 gcattgatat accagtccca tttgtaaata tttacgtacc tttataaatt 1100

 cagttgcatc tgtggcaaaa tttcagacta tttttgcgtc tttcctcatc 1150

 actttttgtg atgcaactcc agtctggact cagatgcata gatttggtcc 1200

 agtgtatttt catgataaag tgaaattgag tcagaacaag agttaatatc 1250

 tgcctgtatc ttgcacagtt cgagcgatct gttattaact gggaagcatt 1300

 tggtgttggt tttcattcca tttcgacgag catgttattg ggaagtattc 1350

 tgaagaggca atagcagtaa taacaacaga cttaagtgct acgccccttt 1400

 gtgctgctgg cttttctggt tgcaggcttt cccatggtca caggatgcac 1450

 tgtcagcatc aggtcccaga gggccaccgt gtccattaca gcagagtcca 1500

 gctgcagcat ccagctcacg ccctcatggg aattggcaca ggcctggggc 1550

 agggcttctg atggccattt gcttggcctc ctgcatttta gtccaactca 1600

 cagtccacta gcttcactcc tttaaattca ctttgaaaca ggcctcatcc 1650

 cacttccacc agcaccatag aagaataatt ctgggcagaa gtctgttttt 1700

 tttcattttt ccaggacagt tggatattgt caggccactt gtgaccccag 1750

 ccatgtagtg agggtgctct ttctctgtgc ctgctcctta tgagtgcagt 1800

 ggaaggaagc cacacactgg tcagtcattt cagaggcagc agatgcccag 1850

 ggagacccaa gaaagagtca ggttagggag cagtgaaagt gaggagggaa 1900

 gacaattctg tgaactctgt aactcttaaa atttttgaaa actccatcgt 1950

 taaacaactt ttaaaagaaa taactaaatt ttcaaatgag taagcagtgc 2000

 caccaactag tgttttgccc gatagaagag ccagcatgtt cacgttattt 2050

 aaattaggtg gaaaaatcta aacattttta tcttcataat ttaaaaaata 2100

 tatatgtata tattgcatat tcactttttc ctttaggtag agatgatttc 2150

 aatccaaata ctcttacttt aaaaaatttc ctttccccaa gaatctcctt 2200

 gggactttga cttattttta aagctgtgtt ggagctcatc ttgttccctg 2250

 atgtgtctcg agcccattgg tagggtcata caaagcccac ggttacaagc 2300

 agtggtagga ttgcagccgt gggcctgctg gacacacaca tacaccaaag 2350

 atgtatttgg atctgggcac cccctcccag gatccctgta ctcacgtgcc 2400

 agtctcctga ctagagcact ttactctgtt tcctcagccc tgcagcccct 2450

 gggagcacac actgggtgca gccctgggcc aggcacggga ggccctgccc 2500

 tgtgctgccc aggggctgtg tgcaccacat gagcacattt ccctctggcc 2550

 tggcggcctc caggctggct gtggaaacag ttcctgagga aattagagat 2600

 tctatgaatt gtaggagtat taaagaccag gctgttggca ccagaactta 2650

 aagcgatgac tggatgtctc tgtactgtat gtatctggtt atcaagatgc 2700

 ctctgtgcag aaagtatgcc tcccgtgggt atacgttttt acctttttta 2750

 aaaaacattt ttgtagaaaa aataattaaa tccccttttt ggaaacttac 2800

 tgcaggtttt gtgccttgac aacctctccc tatgtgaggt ttgtaaaaag 2850

 tgtcctgtga cttaacacag aaacgcaata aacacacaca aaatagtttc 2900

 atgagtgatt cttcagatgc ccttcccaac tggttagttg atcaagaatt 2950

 ttgggggtgg gggttgcgga gaaatcaagt ttaaaattcc ttctgattaa 3000

 aaaaatatag tggaatacaa ttgtctgccg tttccccttc ttaatgtata 3050

 tattgtgagt atttattaga ttcgtaggtc atattactta tcaactgagc 3100

 caaatgtctg tgtgcaattg tgtttccttt accttgtaaa attttgtaca 3150

 gcataaataa gtaaaaaaat cactgttttt ctcaactttt tcaaaatcaa 3200

 ggattgtaaa tattgtagat tctttttctg tgtgatgtgt cctactgttt 3250

 cataatgctg taacttgtag aaatattgta tatttatttt ctgcttattt 3300

 aatgtcttaa tttctgaaaa gtattaacat ccctgtctcc cactcccctg 3350

 ccgtcccatg aagttaactc ctgagagttg tcgggggtga ctggagagct 3400

 cattgcagac cacgtggtcc tccagggtgg ctctccacct tcgggtcctg 3450

 gtatttccag tcaagtgggt ttcaattctt gggctttgcc gcccttatga 3500

 tgaagtgtgt gtttgatgcc agtgagaaac tcagtctggc aggctacaaa 3550

 attctactcc aagaaatacc cagcaacctt ctgtttgttc caaagcaact 3600

 agcttatcat gcaagcaaat tttgctgact ccaggcttta tctttaggaa 3650

 aacaaaaaaa ccaaagtatt atcagcaggt gggaaagatt tttctattga 3700

 aaatttatcc ctgacaactc agcgtttaga aaagaaataa aatgtgccac 3750

 ttccagaggt gctgcattgc agttgttcag ggctagggcc aggcaggaca 3800

 agtgaatggg tgggacaggt ggctcctgcc taaggaccac ctcaggccac 3850

 taaccccttg tggacaactg tgagtagctg ggttttcccc cacctgctgt 3900

 gcaacttcct gtgctttgag gttggactaa cttgtcttca ggagctaatt 3950

 aactgtacag ccctccccac gccccaccca tacggtcact gcatttggtc 4000

 agcctgcttc ttcaggtcga tgccctcctt ctgatactcc atctccttca 4050

 ggggaggttg gggccccact ggactgggtg tcaagatgtg aaagcttatg 4100

 ggagctttaa ggagacttca tggtggttcc atgcaggtgg ttctgccatc 4150

 cctgctgatt tagcctggtg cctgtgtgtg tccactcacg tacacgtggg 4200

 gtgggggaaa cgtgtctaca gatgacgcta aatcagttgg ggtctactct 4250

 aaacagcatt gtgtgtaaga agcatcctca agctcccagt taagtaactt 4300

 gactactttt atttgggaat ttcagactat agaagctctc ttatgtttta 4350

 tgtccagatt ctgtgaccac tagttactgt atcagaactc atcaggtacc 4400

 cacttataaa tagcactgat ctggctgtat actgatccat cactaacctg 4450

 ttttctagga cccagcgtat gtagcatttg tattgcagtt tccctggctt 4500

 acttgtgttt tgcactgatg aattttgaca gggtaattgc cactttactt 4550

 gtgcaatact gctgtaaata actgcagatt tttaaacaat cttttatgtt 4600

 aattttataa aaataaaact ttcaactagt tttaaacaaa ac 4642

<210> 4212
<211> 138
<212> PRT
<213> Homo sapien

<400> 4212
 Met Ala Lys Gln Pro Ser Asp Val Ser Ser Glu Cys Asp Arg Glu
   1               5                  10                  15

 Gly Arg Gln Leu Gln Pro Ala Glu Arg Pro Pro Gln Leu Arg Pro
                  20                  25                  30

 Gly Ala Pro Thr Ser Leu Gln Thr Glu Pro Gln Asp Arg Ser Pro
                  35                  40                  45

 Ala Pro Met Ser Cys Asp Lys Ser Thr Gln Thr Pro Ser Pro Pro
                  50                  55                  60

 Cys Gln Ala Phe Asn His Tyr Leu Ser Ala Met Ala Ser Met Arg
                  65                  70                  75

 Gln Ala Glu Pro Ala Asp Met Arg Pro Glu Ile Trp Ile Ala Gln
                  80                  85                  90

 Glu Leu Arg Arg Ile Gly Asp Glu Phe Asn Ala Tyr Tyr Ala Arg
                  95                 100                 105

 Arg Val Phe Leu Asn Asn Tyr Gln Ala Ala Glu Asp His Pro Arg
                 110                 115                 120

 Met Val Ile Leu Arg Leu Leu Arg Tyr Ile Val Arg Leu Val Trp
                 125                 130                 135

 Arg Met His


<210> 4213
<211> 5496
<212> DNA
<213> Homo sapien

<400> 4213
 gtggaagcca gctctccagg ccacggaagt cctctgagca gcctgttacc 50

 ttctgcctca gtgccagagt ccatgacaat tagtgaactg cgccaggcca 100

 ctgtggccat gatgaacagg aaggatgagc tggaggagga gaacagatca 150

 ctgcgaaacc tgctcgacgg tgagatggag cactcagccg cgctccggca 200

 agaggtggac accttgaaaa ggaaggtggc tgaacaggag gagcggcagg 250

 gcatgaaggt ccaggcgctg gccagagaga acgaggtgct caaagtccaa 300

 ctgaagaaat atgtaggagc tgtccagatg ctgaaaagag aaggtcaaac 350

 agctgaagtg ccaaatcttt ggagtgttga tggagaagtt acagtagctg 400

 aacagaagcc gggagaaatt gctgaagaac tcgcaagctc ctacgaaaga 450

 aagctcatcg aggtggcaga gatgcatggc gagctgattg agttcaacga 500

 gcgcctgcac agggccctgg tagccaagga agccctcgtg tcccagatga 550

 ggcaggagct catcgatctc cggggaccgg tgcctggaga tttgagtcaa 600

 acgtccgaag accagagttt gtcggatttt gaaatatcaa accgggcgct 650

 gatcaacgtc tggatcccct cagtgtttct ccggggcaaa gcagcaaatg 700

 cattccacgt gtatcaggtc tacatccgga taaaagacga tgaatggaat 750

 atttatcgcc ggtatacaga gttcaggagt ttgcaccaca agttacaaaa 800

 caagtaccct caagtgaggg cctacaactt cccacccaaa aaggccattg 850

 gaaacaagga tgccaagttt gtggaggaac ggagaaagca gctccagaat 900

 tacctgcgca gcgtcatgaa caaagtcatc cagatggtcc ccgagttcgc 950

 tgccagcccc aagaaggaga ccctcatcca gctgatgccc ttcttcgtcg 1000

 acatcacccc gcccggagag cctgtgaaca gccggcccaa agcagcttcc 1050

 cgcttcccca aactgtcccg gggtcagccc cgggagaccc gcaacgtgga 1100

 gccccagagc ggtgacctct gacctcgaca aaaccgcagc cacgggccct 1150

 gtgcgtggca ccagctgcgt ccaccccagc cactgccgct ggcccctcac 1200

 ctcagcgtga caaccacgtc cacctggtga tcctgagagc acacgattcc 1250

 caacagttac acaacacccc gattaaacta atcagtcttc gagccgcatg 1300

 ataccgtgac ccgagagacc aaggcagcac ctcgctggag agactgggac 1350

 acacagtcct tctgcttctg gggtctaccc tgggctgcaa gggctgttcc 1400

 tccacctttc tgtagttcag ggctggcagg agggtgggca ccaggtcagg 1450

 ctgggtgcgc catggttgag aggcaaaggt gatcccctat ataggaaggt 1500

 tcatgcagag ccagcctctc cactctttcc cacgtgggga ctaaaatgac 1550

 tattagcctc tccttttgct ttttaaggtt attacctggc ctaacctagg 1600

 gatggctggc ttttgggggg ggggggtggg catggttcct ttcactgcat 1650

 tttccaccaa cagtcattag acacctggca ctgtcacagc tcacttttcc 1700

 agagggatat tcctgtggct ttggcaagga gccattagtg atgtgcaact 1750

 tgagttcaga gaacttcccc tacctccccc atggctggct tcaggaagga 1800

 ccagtgccct ccatagcctg aggccaccta ggccctcgcc aggcttggag 1850

 tggggggact cagacatctg gcccagccat cagcagcaac ctagtaaccc 1900

 ggcgtcatcc agcgtgtcca aagtagcatt ggccctacag tcatgagaga 1950

 cttgggtcag ggaaccactg cagaaggttc cagggttttc aaaccaggct 2000

 ccatgactat gaagttggac ccagtgtgga cacttaacag atcatgtgtc 2050

 tctccactaa aaacattttc catcccgtct gcccccgaca ttgaccttga 2100

 taacagaact ctgcatcccc taagagtcct ctgttcctcc catgtcaggt 2150

 ggctctcaga gtacagggac cttggcaggt ggagaggagg atggggacca 2200

 gcagctgggc agcccccagg gctcctcctc cagtgagctc acatcagagc 2250

 acctcacaga gcaatagccg tcctcagatg ctcagcaaag ttgtggcagt 2300

 ttgcatttct agggtaaact aactaggaag gatgtcgtga aatggactat 2350

 gcaagagtaa gtttgtgtgt ttcgccttaa tctgaggcag agacacagca 2400

 gaacctgagg acaaaagcag gtggaaggtg acggttagat ggtaagccat 2450

 gggcttgtcc tggaactgct tcaactcagt ggcttaaaat gagaactgcc 2500

 caggtgagca tggagcatct cctaggctcg aggacatctc tggagaatca 2550

 tctggaaggt ttatactgtg ccttcccctc gtagcaaaaa ggaagattgt 2600

 tcatggcctt taaggaaggc tgagatcact cacacacagc gcccccccac 2650

 cccagagaaa ccgagtcagc ctacatgact tccaagggaa cctggggcca 2700

 gataagccct gccccggtga gaccaaatga gctggagcat gtatggaggt 2750

 gcggaccctg caatcagttt gcgagtgtgg aggacccgag acatcctgta 2800

 aaggcaactt ggtctccctc ccactcacct gccaacattg ctgcaataca 2850

 catggtttat ctgaaattcc agggccagag tgcacatcag ctcacatgac 2900

 tggcaactct aaatagagag ccctaatgga ctgaggcagg aaacgtctaa 2950

 aagctcaatc tgctgtatgt catgacccct taggttgggt ttatgccaca 3000

 tcggtcattt tgaagtaggt gtttgatgcc agctcagaga ctgtctcagg 3050

 agtgcctccc tggcctgggt agctacccct ggaggtcatc tccctgttct 3100

 ctgttggata aaggaacctc ccccatctgt gacattccct tgggcccagg 3150

 cttatgacct gcaccttttc tgacacctgc ccccaaagca caggatgtga 3200

 attggtctct ctccagatac cccacgagga agcaccttgg acattctgca 3250

 catgataata atgcaacaga gtcccccatt gctgagagat actaacccgt 3300

 gagaaacaag tatgctctca gctggtattg aactggtggg agaaactgcc 3350

 tcctactttt ataatactga attattcaca aaaaacctgg tctgctctcc 3400

 aaaatgggag catgttcctg ggagccacat ggggaccatc cccagctgcc 3450

 tgctcctggt acctccccca tgatcatgca cagaccgtag agtcgagtca 3500

 tctcgcagat ccagaccatc tcctctcatt ctcactctaa aaatgctggt 3550

 ggcccgccca tgacagcaac tccccgaagc cttccctttg gaatcccata 3600

 gaatgttctg caatgattgg gtccatcttg ctgctcagaa gaatcccgtc 3650

 ctgctctcta gtgtggtggg atgaacttca ggcaacaaac aactggcagg 3700

 gttcccagtt cctggagtta tggagcagaa acacccaggc ctagcagaat 3750

 tgtggctgaa acctggtgcc caaattccac acccctggaa atgtgtcaac 3800

 tgcccgtcag cctggattca attctgaggg ctaagccacg accttatcca 3850

 tgagtggcga agacacccct gagtaaagga ttgcttgcac ctcacatctg 3900

 tcttcttcta agattactcg gagattttca aacaacatct gagaacagaa 3950

 gccccctccc ctactcagag aggaacgagg gtggcccacc tctcaagggc 4000

 cttggattcc tgggaccacc ctttgctggg aggaagaatc cacaccgaat 4050

 ccttctgtct tcatggcctg ctgtgctgaa acagaacagc aggttccatc 4100

 tttcacatct ttttttctcc cccagatgaa agacgactca ggaacggtag 4150

 ggctgggcag aggtgtctct ccttgagaga caacaaaagc ttctaaggga 4200

 gggagcttaa aggctgctag aaacctagcc caaccatcca ctcctgatct 4250

 gagacagaac cttctccgcc actcttcctg caatcagtgt gaaattccag 4300

 cttctttgat tcccacttag cagtatgctc caatcacgtt gctggcaagg 4350

 cattttagag tttggagctg aggttcaaag ccccctgcat ttctctactg 4400

 gcaggccctg gtgaaggaag acactttcag ggaagaggct cttacagtct 4450

 atggtggtag ccatcttcac atccagtcac cagttgcatc tagggagctg 4500

 ctggctataa aagggatcat ccagtggagt tgtaaacaag ggaaccatct 4550

 tgcaagatct aggaagagga aggggaggga tgtggactgg gtcagatcac 4600

 agcccttggc cctgcttcat actttggagc ttattaagat caattttgat 4650

 aaccatgtaa tttcttagaa ccatggcagg tagtattgtg ctttaaaaac 4700

 cagaggctcc tgaaagtcgt ttacaccagg tggattgata ccatggctgt 4750

 agctgatgca actaacaagt actggggcca gtgatcacaa tccagggttg 4800

 gaaacaggag tgaagcccac cagcctgcct ggctgatgga cagcaggctc 4850

 tgccttctgg aggcggctta tatcccaaca gcctgaggca gggctctgtg 4900

 gcccaggcca gcagtggctg cctcttttgg ttctgcatgg tacattttgc 4950

 caaccctgag gaccagttct tggggttcca ggcctcggcc ttcctgctcc 5000

 acgtgctcaa gcccccacat ggggctgcga caccatctgg ctcctcacag 5050

 ggaggtccag ccatgttctc tgggctccca gtgagccccc tgccctccag 5100

 ctacccccag aatccatcct tcattcctcc accaagctcc tgtgtgagct 5150

 gcagcaccca cacgggggaa gccctgcact ccagcagcat cttccagcct 5200

 tggcacagaa ctgatggcaa aggaagggct gggttttcag cttctgggac 5250

 ccgaggaaga ccccacctca ctcctccttc cccagtacat cagactggtt 5300

 aggaggcatc ccagaagggg cagcctcatg cccaggtttc agccctaaag 5350

 gtaatgattg tcttgactct gccttggcat ttcgctcgga atcacggcag 5400

 acttggagtg tttcttcaag gcaggcatct gcttatgagc aaggtcaaag 5450

 atttttcaaa atattgtgca ttaattcatt aaagctactg ttaaat 5496

<210> 4214
<211> 10183
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 7848-7874
<223> Unknown base

<400> 4214
 atcccacaga cagcgctttg agcagaacgc acggctcaac tcatgtaatt 50

 actgtttata gctggccgag cctgactagg agagggcaga cccgagagga 100

 aatcagtttc ccggaccttt gagaggaggc tgtgtgttaa ttaaaggcta 150

 ggacgggacg ggtacttctc agacatgctc caagttgttc ttgagatcac 200

 agttcccatc acattttctc tggagggagt gagtagataa ttgggatttt 250

 ttttttattt ttggccttgt ctttcttcct tttttttacc tctccccatt 300

 ttagtcatat ggccttgaac ccacagtgaa ttgaagagag aaagaaatgg 350

 atatgtctga ccccaatttt tggactgtgc tctcaaactt tactttgcct 400

 catttgagga gtgggaacag gcttcggcga acacaaagtt gccgaacaag 450

 caaccggaaa agcttaatag gcaatgggca gtcaccagca ttgcctcgac 500

 cacactcacc tctctctgct catgcaggaa atagccctca agatagtcca 550

 agaaatttct cccccagtgc ctcagcccat ttttcatttg cacggaggac 600

 tgatggacgc cgctggtcgt tggcttctct cccttcctct ggctatggga 650

 caaacacacc cagctctacg gtctcttcat cctgttcctc ccaggagaag 700

 ttgcatcagt taccatacca accaacacca gacgagttac acttcttatc 750

 aaaacatttc tgtaccaccg aaagcatcgc cactgagaac agatgcagga 800

 acacgccgat gcgcccccgt tcccgaagtc tgagccctgg acgttctccc 850

 gcctgctgtg accatgaaat aattatgatg aaccatgtct acaaagaaag 900

 gttcccaaag gctacagctc agatggaaga acgtctaaag gaaattatca 950

 ccagctactc tcctgacaac gttctaccct tagcagatgg agtgcttagt 1000

 ttcactcacc accagattat tgaactggct cgagattgct tggataaatc 1050

 ccaccagggc ctcatcacct cacgatactt ccttgaatta cagcacaaat 1100

 tagataagtt gctacaggag gctcatgatc gttcagaaag tggagaattg 1150

 gcatttatta aacaactagt tcgaaagatc ctaattgtta ttgcccgccc 1200

 tgctcggtta ttagagtgcc tggaatttga tccggaagaa ttttactacc 1250

 tattggaagc agcagaaggc catgccaaag aaggacaggg tattaaaacc 1300

 gacattccca ggtacatcat tagccaactg ggactcaata aggatccctt 1350

 ggaagaaatg gctcatttgg gaaactacga tagtgggaca gcagaaacac 1400

 cagaaacaga tgaatcagtg agtagctcta atgcctccct gaaacttcga 1450

 aggaaacctc gggaaagtga ttttgaaacg attaaattga ttagcaatgg 1500

 agcctatggg gcagtctact ttgttcggca taaagaatcc cggcagaggt 1550

 ttgccatgaa gaagattaat aaacagaacc tcatccttcg aaaccagatc 1600

 cagcaggcct ttgtggagcg ggatatcctg acttttgcag aaaacccctt 1650

 tgttgtcagc atgtattgct cctttgaaac aaggcgccac ttgtgcatgg 1700

 tcatggaata tgtggaaggg ggagactgtg ctactttaat gaaaaacatg 1750

 ggtcctctcc ctgttgatat ggccagaatg tactttgctg agacggtctt 1800

 ggccttggaa tatttacata attatggaat tgtacacagg gatttgaaac 1850

 cagacaactt gttggttacc tccatggggc acataaagct gacagatttt 1900

 ggattatcta aggtgggact aatgagcatg actaccaacc tttacgaggg 1950

 tcatattgag aaggatgcta gagagttcct ggataaacag gtctgtggca 2000

 cacctgaata cattgcacca gaagtgattc tgaggcaggg ttatggaaag 2050

 ccggtggact ggtgggccat ggggattatc ctctatgaat ttctggttgg 2100

 atgcgtgcca ttctttgggg atactccaga ggagctattt ggacaagtca 2150

 tcagtgatga gatcaactgg cctgagaagg atgaggcacc cccacctgat 2200

 gcccaggatc tgattacctt actcctcagg cagaatcccc tggagaggct 2250

 gggaacaggt ggtgcatatg aagtcaaaca gcatcgattc ttccgttctt 2300

 tagactggaa cagtttgctg agacagaagg cagaatttat tccccaactg 2350

 gaatctgagg atgacacaag ttattttgat actcggtctg agaagtatca 2400

 tcatatggaa acggaggaag aagatgacac aaatgatgaa gactttaatg 2450

 tggaaataag gcagttttct tcatgttcac acaggttttc aaaagttttc 2500

 agcagtatag atcgaatcac tcagaattca gcagaagaga aggaagactc 2550

 tgtggacaaa accaaaagca ccaccttgcc atccacagaa acactgagct 2600

 ggagttcaga atattctgaa atgcaacagc tatcaacatc caactcttca 2650

 gatactgaaa gcaacagaca taaactcagt tctggcctac ttcccaaact 2700

 ggctatttca acagagggag agcaagatga agctgcctcc tgccctggag 2750

 acccccatga ggagccagga aagccagccc ttcctcctga agagtgtgcc 2800

 caggaggagc ctgaggtcac caccccagcc agcaccatca gcagctccac 2850

 cctgtcagtt ggcagttttt cagagcactt ggatcagata aatggacgaa 2900

 gcgagtgtgt ggacagtaca gataattcct caaagccatc cagtgaaccc 2950

 gcttctcaca tggctcggca gcgattagaa agcacagaaa aaaagaaaat 3000

 ctcggggaaa gtcacaaagt ccctctctgc cagtgctctt tccctcatga 3050

 tcccaggaga tatgtttgct gtttcccctc tgggaagtcc aatgtctccc 3100

 cattccctgt cctcggaccc ttcttcttca cgagattcct ctcccagccg 3150

 agattcctca gcagcttctg ccagtccaca tcagccgatt gtgatccaca 3200

 gttcggggaa gaactacggc tttaccatcc gagccatccg ggtgtatgtg 3250

 ggagacagtg acatctatac agtgcaccat atcgtctgga atgtagaaga 3300

 aggaagtccg gcatgccagg caggactgaa ggctggagat cttatcactc 3350

 ccatcaatgg agaaccagtg catggacttg tccacacaga agttatagaa 3400

 ctcctactga agagtgggaa taaggtgtca atcactacta ccccatttga 3450

 aaacacatca atcaaaactg gaccagccag gagaaacagc tataagagcc 3500

 ggatggtgag gcggagcaag aaatccaaga agaaagaaag tctcgaaagg 3550

 aggagatctc ttttcaaaaa gctagccaag cagccttctc ctttactcca 3600

 caccagccga agtttctcct gcttgaacag atccctgtca tcgggtgaga 3650

 gcctcccagg ttcccccact catagcttgt ctccccggtc tccaacacca 3700

 agctaccgct ccacccctga cttcccatct ggtactaatt cctcccagag 3750

 cagctcccct agttctagtg cccccaattc cccagcaggg tccgggcaca 3800

 tccggcccag cactctccac ggtcttgcac ccaaactcgg cgggcagcgg 3850

 taccggtccg gaaggcgaaa gtccgccggc aacatcccac tgtccccgct 3900

 ggcccggacg ccctctccaa ccccgcaacc cacctccccg cagcggtcac 3950

 catcccctct tctgggacac tcactgggca attccaagat cgcgcaagcc 4000

 tttcccagca agatgcactc cccgcccacc atcgtcagac acatcgtgag 4050

 gcccaagagt gcggagcccc ccaggtcccc gctgctcaag cgcgtgcagt 4100

 ccgaggagaa gctgtcgccc tcttacggca gtgacaagaa gcacctgtgc 4150

 tcccgcaagc acagcctgga ggtgacccaa gaggaggtgc agcgggagca 4200

 gtcccagcgg gaggcgccgc tgcagagcct ggatgagaac gtgtgcgacg 4250

 tgccgccgct cagccgcgcc cggccagtgg agcaaggctg cctgaaacgc 4300

 ccagtctccc ggaaggtggg ccgccaggag tctgtggacg acctggaccg 4350

 cgacaagctg aaggccaagg tggtggtgaa gaaagcagac ggcttcccag 4400

 agaaacagga atcccaccag aaatcccatg gacccgggag tgatttggaa 4450

 aactttgctc tgtttaagct ggaagagaga gagaagaaag tctatccgaa 4500

 ggctgtggaa aggtcaagta cttttgaaaa caaagcgtct atgcaggagg 4550

 cgccaccgct gggcagcctg ctgaaggatg ctcttcacaa gcaggccagc 4600

 gtgcgcgcca gcgagggtgc gatgtcggat ggcccggtgc ctgcggagca 4650

 ccgccagggt ggcggggact tcagacgggc ccccgctcct ggcaccctcc 4700

 aggatggtct ctgccactcc ctcgacaggg gcatctctgg gaagggggaa 4750

 ggcacggaga agtcctccca ggccaaggag cttctccgat gtgaaaagtt 4800

 agacagcaag ctggccaaca tcgattacct ccgaaagaaa atgtcacttg 4850

 aggacaaaga ggacaacctc tgccctgtgc tgaagcccaa gatgacagct 4900

 ggctcccacg aatgcctgcc agggaaccca gtccgaccca cgggtgggca 4950

 gcaggagccc ccgccggctt ctgagagccg agcttttgtc agcagcaccc 5000

 atgcagctca gatgagtgcc gtctcttttg ttcccctcaa ggccttaaca 5050

 ggccgggtgg acagtggaac ggagaagcct ggcttggttg ctcctgagtc 5100

 ccctgttagg aagagcccct ccgagtataa gctggaaggt aggtctgtct 5150

 catgcctgaa gccgatcgag ggcactctgg acattgctct cctgtccgga 5200

 cctcaggcct ccaagacaga actgccttcc ccagagtctg cacagagccc 5250

 cagcccaagt ggtgacgtga gggcctctgt gccaccagtt ctccccagca 5300

 gcagtgggaa aaagaacgat accaccagtg caagagagct ttctccttcc 5350

 agcttaaaga tgaataaatc ctacctgctg gagccttggt tcctgccccc 5400

 cagccgaggt ctccagaatt caccagcagt ttccctgcct gacccagagt 5450

 tcaagaggga caggaaaggt ccccatccta ctgccaggag ccctggaaca 5500

 gtcatggaaa gcaatcccca acagagagag ggcagctccc ctaaacacca 5550

 agaccacacc actgacccca agcttctgac ctgcctgggg cagaacctcc 5600

 acagccctga cctggccagg ccacgctgcc cgctcccacc tgaagcttcc 5650

 ccctcaaggg agaagccagg cctgagggaa tcgtctgaaa gaggccctcc 5700

 cacagccaga agcgagcgct ctgctgcgag ggctgacaca tgcagagagc 5750

 cctccatgga actgtgcttt ccagaaactg cgaaaaccag tgacaactcc 5800

 aaaaatctcc tctctgtggg aaggacccac ccagatttct atacacagac 5850

 ccaggccatg gagaaagcat gggcgccggg tgggaaaacg aaccacaaag 5900

 atggcccagg tgaggcgagg cccccgccca gagacaactc ctctctgcac 5950

 tcagctggaa ttccctgtga gaaggagctg ggcaaggtga ggcgtggcgt 6000

 ggaacccaag cccgaagcgc ttcttgccag gcggtctctg cagccacctg 6050

 gaattgagag tgagaagagt gaaaagctct ccagtttccc atctttgcag 6100

 aaagatggtg ccaaggaacc tgaaaggaag gagcagcctc tacaaaggca 6150

 tcccagcagc atccctccgc cccctctgac ggccaaagac ctgtccagcc 6200

 cggctgccag gcagcattgc agttccccaa gccacgcttc tggcagagag 6250

 ccgggggcca agcccagcac tgcagagccc agctcgagcc cccaggaccc 6300

 tcccaagcct gttgctgcgc acagtgaaag cagcagccac aagccccggc 6350

 ctggccctga cccgggccct ccaaagacta agcaccccga ccggtccctc 6400

 tcctctcaga aaccaagtgt cggggccaca aagggcaaag agcctgccac 6450

 tcagtccctc ggtggctcta gcagagaggg gaagggccac agtaagagtg 6500

 ggccggatgt gtttcctgct accccaggct cccagaacaa agccagcgat 6550

 gggattggcc agggagaagg tgggccctct gtcccactgc acactgacag 6600

 ggctcctcta gacgccaagc cacaacccac cagtggtggg cggcccctgg 6650

 aggtgctgga gaagcctgtg catttgccaa ggccgggaca cccagggcct 6700

 agtgagccag cggaccagaa actgtccgct gttggtgaaa agcaaaccct 6750

 gtctccaaag caccccaaac catccactgt gaaagattgc cccaccctgt 6800

 gcaaacagac agacaacaga cagacagaca aaagcccgag tcagccggcc 6850

 gccaacaccg acagaagggc ggaagggaag aaatgcactg aagcacttta 6900

 tgctccagca gagggcgaca agctcgaggc cggcctttcc tttgtgcata 6950

 gcgagaaccg gttgaaaggc gcggagcggc cagccgcggg ggtggggaag 7000

 ggcttccctg aggccagagg gaaagggccc ggtccccaga agccaccgac 7050

 ggaggcagac aagcccaatg gcatgaaacg gtccccctca gccactgggc 7100

 agagttcttt ccgatccacg gccctcccgg aaaagtctct gagctgctcc 7150

 tccagcttcc ctgaaaccag ggccggagtt agagaggcct ctgcagccag 7200

 cagcgacacc tcttctgcca aggccgccgg gggcatgctg gagcttccag 7250

 cccccagcaa cagggaccat aggaaggctc agcctgccgg ggagggccga 7300

 acccacatga caaagagtga ctccctgccc tccttccggg tctccaccct 7350

 gcctctggag tcacaccacc ccgacccaaa caccatgggc ggggccagcc 7400

 accgggacag ggctctctcg gtgactgcca ccgtagggga aaccaaaggg 7450

 aaggaccctg ccccagccca gcctccccca gctaggaaac agaacgtggg 7500

 cagagacgtg accaagccat ccccagcccc aaacactgac cgccccatct 7550

 ctctttctaa tgagaaggac tttgtggtac ggcagaggcg ggggaaagag 7600

 agtttgcgta gcagccctca caaaaaggcc ttgtaacggg gagggcccag 7650

 gggcaggact gtggagaccc gtcctgaacg ggcgactgtg tcttgactac 7700

 ctttcaaaac cagcactgtg tgggaatgtc cgccaggcag agctcggagc 7750

 ctcattgaga caggggagag agaaagacaa agaggggacc ttcttccaga 7800

 tgccttccca gttgtaaccg gtaaaactgt taccagatag tgtttgtnnn 7850

 nnnnnnnnnn nnnnnnnnnn nnnnaaaatt acctttacag ttgagggttg 7900

 ttgaggaaaa tgattttctt tgtaaatata tagcatcgtg tttggtttgg 7950

 gatgtagagt ctatacctgg ctgctgattg cgtcgtttac tacagctttt 8000

 tttaaataag atttttgctt taccatttat cataatgtag taatgaagca 8050

 aaatggtcaa aactgggtgt gtgtgaacag agatacaccc atattcgtgt 8100

 atatacacat ccacctacat gttttggtct gtggtttaag agactatttc 8150

 aaggttccat ttttataagc taaaacattc taagttaaga tggaagaaag 8200

 ccctaaacac agtagattct gagtttttat gtgtatttta accagagttt 8250

 ctgatagtac tgtatctggc tacctatatt tccagatcta aagcaagaac 8300

 tactctaagt actgcatttg gaatcctcct ccattaggaa tggccaggac 8350

 aagtggagct agccattttc attacacggc catcccaatg gacactggat 8400

 ccctggtcca actgtctaaa aggccagttg ttcctttctg tggatgtgga 8450

 tgtctggcct tcacctgagg tagagcgggg actataaaca cacatcaact 8500

 ttctttctgt ttgctttctt ttccttcttt tcaaactctt aaactcaggc 8550

 ctttatgctg tgagtgacta gtccaagaag cacacatttt gtagtagtcc 8600

 tgcaccagcc ctgctcttga ataaaaagga aaattactgg ctgcacccaa 8650

 atcttctagt acttgagtaa taagcatcag gcattggaag aggttttaaa 8700

 tttgcttttt tgaggaaaag aactgggggt ggattttggc atcgtagcat 8750

 atcgattaaa gaataatcag gacatcagat acattttaat acatagctgg 8800

 ggccttatgt tgtagatgaa gcttgctgtt tttagcaagt tcctgggttt 8850

 cacattcatt tctgctgcat ctagtagctc cacacatttc ataacctgat 8900

 ctctttattt gtatgcaaaa aatactgtct taatacagag cagcattttt 8950

 gtaacaaaga gactcgctgg agctatttgg tgcttgaatg tgaccatcct 9000

 ttttactttt gctaagcctt atttaaattt tgtataccgt ggaatatgta 9050

 gaatttgtca aatcatttta gtgctgaagg tttttgattt cttgtttttg 9100

 tttctgttgt tgcagtttct ttggtggctt gttttgtatt gtaagatggc 9150

 acttgctgat ataaatacta aggcactaag agaaaataca gataagtatt 9200

 tataagttgc ttgggaacca tagcagaatt ttttgtttgg ttttgtaaga 9250

 gaaaaaaaat taccaataaa taactgatct agcacccaaa ctctcttggg 9300

 ggatgtctta gtatcttcac gctataaaat tgttcatcta agcacagcat 9350

 catcttatgg ccttatggat tgtaaatctt ctagtgaggc tataaactcc 9400

 actctgaaaa caaaggcata acttaaccga ctgctcagtt gtccttcgtt 9450

 gtaaaatgaa ttggctttgg gaaaaaggaa aaaaacaaac aaaaaaagaa 9500

 aaagaaaaaa gcctcctcct tgcccctaat ttttttttcc catatggttt 9550

 tagccattcc ccatcactat attgtgaagc tgtaaaaata tatatatata 9600

 ctttacaaga gtttactaat ggatttcaaa actggtctca acgtttataa 9650

 tacatatctg tgtttggcag ttgtcataac ccaatcctac attcagccat 9700

 cgggacaagt ctgtcgggga ggtagttcat ggtttacaag cctttgcttt 9750

 ttaactgtcc aatttccttt aaagcacaac tagctatttg tttacaaatg 9800

 atatttttat gtatattttg tatagtgtat catcattttt gccaaatatg 9850

 tttttcatta taaatgagta aagagtactt aaggttgcat tcatgtatta 9900

 catgtttgtt gttgtaaacc tctccaatca gctggtagaa attctcctca 9950

 ttgtgttcta tttggtcagt ctctgtgtga ttgtaggatg tgctccttgg 10000

 tagtactccc agctgtagat ttaccagctt aaaagtttgt taggatctgt 10050

 gcaataaagt gtttgcagtc ttattttctc taagaaattc cttatggacg 10100

 tcataattgt tgtatattga acaaaatatt tatacttatg cagttgcata 10150

 acattgaaat aaaaatttag catgaaaaga taa 10183

<210> 4215
<211> 2429
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 7848-7874
<223> Unknown amino acid

<400> 4215
 Met Asp Met Ser Asp Pro Asn Phe Trp Thr Val Leu Ser Asn Phe
   1               5                  10                  15

 Thr Leu Pro His Leu Arg Ser Gly Asn Arg Leu Arg Arg Thr Gln
                  20                  25                  30

 Ser Cys Arg Thr Ser Asn Arg Lys Ser Leu Ile Gly Asn Gly Gln
                  35                  40                  45

 Ser Pro Ala Leu Pro Arg Pro His Ser Pro Leu Ser Ala His Ala
                  50                  55                  60

 Gly Asn Ser Pro Gln Asp Ser Pro Arg Asn Phe Ser Pro Ser Ala
                  65                  70                  75

 Ser Ala His Phe Ser Phe Ala Arg Arg Thr Asp Gly Arg Arg Trp
                  80                  85                  90

 Ser Leu Ala Ser Leu Pro Ser Ser Gly Tyr Gly Thr Asn Thr Pro
                  95                 100                 105

 Ser Ser Thr Val Ser Ser Ser Cys Ser Ser Gln Glu Lys Leu His
                 110                 115                 120

 Gln Leu Pro Tyr Gln Pro Thr Pro Asp Glu Leu His Phe Leu Ser
                 125                 130                 135

 Lys His Phe Cys Thr Thr Glu Ser Ile Ala Thr Glu Asn Arg Cys
                 140                 145                 150

 Arg Asn Thr Pro Met Arg Pro Arg Ser Arg Ser Leu Ser Pro Gly
                 155                 160                 165

 Arg Ser Pro Ala Cys Cys Asp His Glu Ile Ile Met Met Asn His
                 170                 175                 180

 Val Tyr Lys Glu Arg Phe Pro Lys Ala Thr Ala Gln Met Glu Glu
                 185                 190                 195

 Arg Leu Lys Glu Ile Ile Thr Ser Tyr Ser Pro Asp Asn Val Leu
                 200                 205                 210

 Pro Leu Ala Asp Gly Val Leu Ser Phe Thr His His Gln Ile Ile
                 215                 220                 225

 Glu Leu Ala Arg Asp Cys Leu Asp Lys Ser His Gln Gly Leu Ile
                 230                 235                 240

 Thr Ser Arg Tyr Phe Leu Glu Leu Gln His Lys Leu Asp Lys Leu
                 245                 250                 255

 Leu Gln Glu Ala His Asp Arg Ser Glu Ser Gly Glu Leu Ala Phe
                 260                 265                 270

 Ile Lys Gln Leu Val Arg Lys Ile Leu Ile Val Ile Ala Arg Pro
                 275                 280                 285

 Ala Arg Leu Leu Glu Cys Leu Glu Phe Asp Pro Glu Glu Phe Tyr
                 290                 295                 300

 Tyr Leu Leu Glu Ala Ala Glu Gly His Ala Lys Glu Gly Gln Gly
                 305                 310                 315

 Ile Lys Thr Asp Ile Pro Arg Tyr Ile Ile Ser Gln Leu Gly Leu
                 320                 325                 330

 Asn Lys Asp Pro Leu Glu Glu Met Ala His Leu Gly Asn Tyr Asp
                 335                 340                 345

 Ser Gly Thr Ala Glu Thr Pro Glu Thr Asp Glu Ser Val Ser Ser
                 350                 355                 360

 Ser Asn Ala Ser Leu Lys Leu Arg Arg Lys Pro Arg Glu Ser Asp
                 365                 370                 375

 Phe Glu Thr Ile Lys Leu Ile Ser Asn Gly Ala Tyr Gly Ala Val
                 380                 385                 390

 Tyr Phe Val Arg His Lys Glu Ser Arg Gln Arg Phe Ala Met Lys
                 395                 400                 405

 Lys Ile Asn Lys Gln Asn Leu Ile Leu Arg Asn Gln Ile Gln Gln
                 410                 415                 420

 Ala Phe Val Glu Arg Asp Ile Leu Thr Phe Ala Glu Asn Pro Phe
                 425                 430                 435

 Val Val Ser Met Tyr Cys Ser Phe Glu Thr Arg Arg His Leu Cys
                 440                 445                 450

 Met Val Met Glu Tyr Val Glu Gly Gly Asp Cys Ala Thr Leu Met
                 455                 460                 465

 Lys Asn Met Gly Pro Leu Pro Val Asp Met Ala Arg Met Tyr Phe
                 470                 475                 480

 Ala Glu Thr Val Leu Ala Leu Glu Tyr Leu His Asn Tyr Gly Ile
                 485                 490                 495

 Val His Arg Asp Leu Lys Pro Asp Asn Leu Leu Val Thr Ser Met
                 500                 505                 510

 Gly His Ile Lys Leu Thr Asp Phe Gly Leu Ser Lys Val Gly Leu
                 515                 520                 525

 Met Ser Met Thr Thr Asn Leu Tyr Glu Gly His Ile Glu Lys Asp
                 530                 535                 540

 Ala Arg Glu Phe Leu Asp Lys Gln Val Cys Gly Thr Pro Glu Tyr
                 545                 550                 555

 Ile Ala Pro Glu Val Ile Leu Arg Gln Gly Tyr Gly Lys Pro Val
                 560                 565                 570

 Asp Trp Trp Ala Met Gly Ile Ile Leu Tyr Glu Phe Leu Val Gly
                 575                 580                 585

 Cys Val Pro Phe Phe Gly Asp Thr Pro Glu Glu Leu Phe Gly Gln
                 590                 595                 600

 Val Ile Ser Asp Glu Ile Asn Trp Pro Glu Lys Asp Glu Ala Pro
                 605                 610                 615

 Pro Pro Asp Ala Gln Asp Leu Ile Thr Leu Leu Leu Arg Gln Asn
                 620                 625                 630

 Pro Leu Glu Arg Leu Gly Thr Gly Gly Ala Tyr Glu Val Lys Gln
                 635                 640                 645

 His Arg Phe Phe Arg Ser Leu Asp Trp Asn Ser Leu Leu Arg Gln
                 650                 655                 660

 Lys Ala Glu Phe Ile Pro Gln Leu Glu Ser Glu Asp Asp Thr Ser
                 665                 670                 675

 Tyr Phe Asp Thr Arg Ser Glu Lys Tyr His His Met Glu Thr Glu
                 680                 685                 690

 Glu Glu Asp Asp Thr Asn Asp Glu Asp Phe Asn Val Glu Ile Arg
                 695                 700                 705

 Gln Phe Ser Ser Cys Ser His Arg Phe Ser Lys Val Phe Ser Ser
                 710                 715                 720

 Ile Asp Arg Ile Thr Gln Asn Ser Ala Glu Glu Lys Glu Asp Ser
                 725                 730                 735

 Val Asp Lys Thr Lys Ser Thr Thr Leu Pro Ser Thr Glu Thr Leu
                 740                 745                 750

 Ser Trp Ser Ser Glu Tyr Ser Glu Met Gln Gln Leu Ser Thr Ser
                 755                 760                 765

 Asn Ser Ser Asp Thr Glu Ser Asn Arg His Lys Leu Ser Ser Gly
                 770                 775                 780

 Leu Leu Pro Lys Leu Ala Ile Ser Thr Glu Gly Glu Gln Asp Glu
                 785                 790                 795

 Ala Ala Ser Cys Pro Gly Asp Pro His Glu Glu Pro Gly Lys Pro
                 800                 805                 810

 Ala Leu Pro Pro Glu Glu Cys Ala Gln Glu Glu Pro Glu Val Thr
                 815                 820                 825

 Thr Pro Ala Ser Thr Ile Ser Ser Ser Thr Leu Ser Val Gly Ser
                 830                 835                 840

 Phe Ser Glu His Leu Asp Gln Ile Asn Gly Arg Ser Glu Cys Val
                 845                 850                 855

 Asp Ser Thr Asp Asn Ser Ser Lys Pro Ser Ser Glu Pro Ala Ser
                 860                 865                 870

 His Met Ala Arg Gln Arg Leu Glu Ser Thr Glu Lys Lys Lys Ile
                 875                 880                 885

 Ser Gly Lys Val Thr Lys Ser Leu Ser Ala Ser Ala Leu Ser Leu
                 890                 895                 900

 Met Ile Pro Gly Asp Met Phe Ala Val Ser Pro Leu Gly Ser Pro
                 905                 910                 915

 Met Ser Pro His Ser Leu Ser Ser Asp Pro Ser Ser Ser Arg Asp
                 920                 925                 930

 Ser Ser Pro Ser Arg Asp Ser Ser Ala Ala Ser Ala Ser Pro His
                 935                 940                 945

 Gln Pro Ile Val Ile His Ser Ser Gly Lys Asn Tyr Gly Phe Thr
                 950                 955                 960

 Ile Arg Ala Ile Arg Val Tyr Val Gly Asp Ser Asp Ile Tyr Thr
                 965                 970                 975

 Val His His Ile Val Trp Asn Val Glu Glu Gly Ser Pro Ala Cys
                 980                 985                 990

 Gln Ala Gly Leu Lys Ala Gly Asp Leu Ile Thr Pro Ile Asn Gly
                 995                1000                1005

 Glu Pro Val His Gly Leu Val His Thr Glu Val Ile Glu Leu Leu
                1010                1015                1020

 Leu Lys Ser Gly Asn Lys Val Ser Ile Thr Thr Thr Pro Phe Glu
                1025                1030                1035

 Asn Thr Ser Ile Lys Thr Gly Pro Ala Arg Arg Asn Ser Tyr Lys
                1040                1045                1050

 Ser Arg Met Val Arg Arg Ser Lys Lys Ser Lys Lys Lys Glu Ser
                1055                1060                1065

 Leu Glu Arg Arg Arg Ser Leu Phe Lys Lys Leu Ala Lys Gln Pro
                1070                1075                1080

 Ser Pro Leu Leu His Thr Ser Arg Ser Phe Ser Cys Leu Asn Arg
                1085                1090                1095

 Ser Leu Ser Ser Gly Glu Ser Leu Pro Gly Ser Pro Thr His Ser
                1100                1105                1110

 Leu Ser Pro Arg Ser Pro Thr Pro Ser Tyr Arg Ser Thr Pro Asp
                1115                1120                1125

 Phe Pro Ser Gly Thr Asn Ser Ser Gln Ser Ser Ser Pro Ser Ser
                1130                1135                1140

 Ser Ala Pro Asn Ser Pro Ala Gly Ser Gly His Ile Arg Pro Ser
                1145                1150                1155

 Thr Leu His Gly Leu Ala Pro Lys Leu Gly Gly Gln Arg Tyr Arg
                1160                1165                1170

 Ser Gly Arg Arg Lys Ser Ala Gly Asn Ile Pro Leu Ser Pro Leu
                1175                1180                1185

 Ala Arg Thr Pro Ser Pro Thr Pro Gln Pro Thr Ser Pro Gln Arg
                1190                1195                1200

 Ser Pro Ser Pro Leu Leu Gly His Ser Leu Gly Asn Ser Lys Ile
                1205                1210                1215

 Ala Gln Ala Phe Pro Ser Lys Met His Ser Pro Pro Thr Ile Val
                1220                1225                1230

 Arg His Ile Val Arg Pro Lys Ser Ala Glu Pro Pro Arg Ser Pro
                1235                1240                1245

 Leu Leu Lys Arg Val Gln Ser Glu Glu Lys Leu Ser Pro Ser Tyr
                1250                1255                1260

 Gly Ser Asp Lys Lys His Leu Cys Ser Arg Lys His Ser Leu Glu
                1265                1270                1275

 Val Thr Gln Glu Glu Val Gln Arg Glu Gln Ser Gln Arg Glu Ala
                1280                1285                1290

 Pro Leu Gln Ser Leu Asp Glu Asn Val Cys Asp Val Pro Pro Leu
                1295                1300                1305

 Ser Arg Ala Arg Pro Val Glu Gln Gly Cys Leu Lys Arg Pro Val
                1310                1315                1320

 Ser Arg Lys Val Gly Arg Gln Glu Ser Val Asp Asp Leu Asp Arg
                1325                1330                1335

 Asp Lys Leu Lys Ala Lys Val Val Val Lys Lys Ala Asp Gly Phe
                1340                1345                1350

 Pro Glu Lys Gln Glu Ser His Gln Lys Ser His Gly Pro Gly Ser
                1355                1360                1365

 Asp Leu Glu Asn Phe Ala Leu Phe Lys Leu Glu Glu Arg Glu Lys
                1370                1375                1380

 Lys Val Tyr Pro Lys Ala Val Glu Arg Ser Ser Thr Phe Glu Asn
                1385                1390                1395

 Lys Ala Ser Met Gln Glu Ala Pro Pro Leu Gly Ser Leu Leu Lys
                1400                1405                1410

 Asp Ala Leu His Lys Gln Ala Ser Val Arg Ala Ser Glu Gly Ala
                1415                1420                1425

 Met Ser Asp Gly Pro Val Pro Ala Glu His Arg Gln Gly Gly Gly
                1430                1435                1440

 Asp Phe Arg Arg Ala Pro Ala Pro Gly Thr Leu Gln Asp Gly Leu
                1445                1450                1455

 Cys His Ser Leu Asp Arg Gly Ile Ser Gly Lys Gly Glu Gly Thr
                1460                1465                1470

 Glu Lys Ser Ser Gln Ala Lys Glu Leu Leu Arg Cys Glu Lys Leu
                1475                1480                1485

 Asp Ser Lys Leu Ala Asn Ile Asp Tyr Leu Arg Lys Lys Met Ser
                1490                1495                1500

 Leu Glu Asp Lys Glu Asp Asn Leu Cys Pro Val Leu Lys Pro Lys
                1505                1510                1515

 Met Thr Ala Gly Ser His Glu Cys Leu Pro Gly Asn Pro Val Arg
                1520                1525                1530

 Pro Thr Gly Gly Gln Gln Glu Pro Pro Pro Ala Ser Glu Ser Arg
                1535                1540                1545

 Ala Phe Val Ser Ser Thr His Ala Ala Gln Met Ser Ala Val Ser
                1550                1555                1560

 Phe Val Pro Leu Lys Ala Leu Thr Gly Arg Val Asp Ser Gly Thr
                1565                1570                1575

 Glu Lys Pro Gly Leu Val Ala Pro Glu Ser Pro Val Arg Lys Ser
                1580                1585                1590

 Pro Ser Glu Tyr Lys Leu Glu Gly Arg Ser Val Ser Cys Leu Lys
                1595                1600                1605

 Pro Ile Glu Gly Thr Leu Asp Ile Ala Leu Leu Ser Gly Pro Gln
                1610                1615                1620

 Ala Ser Lys Thr Glu Leu Pro Ser Pro Glu Ser Ala Gln Ser Pro
                1625                1630                1635

 Ser Pro Ser Gly Asp Val Arg Ala Ser Val Pro Pro Val Leu Pro
                1640                1645                1650

 Ser Ser Ser Gly Lys Lys Asn Asp Thr Thr Ser Ala Arg Glu Leu
                1655                1660                1665

 Ser Pro Ser Ser Leu Lys Met Asn Lys Ser Tyr Leu Leu Glu Pro
                1670                1675                1680

 Trp Phe Leu Pro Pro Ser Arg Gly Leu Gln Asn Ser Pro Ala Val
                1685                1690                1695

 Ser Leu Pro Asp Pro Glu Phe Lys Arg Asp Arg Lys Gly Pro His
                1700                1705                1710

 Pro Thr Ala Arg Ser Pro Gly Thr Val Met Glu Ser Asn Pro Gln
                1715                1720                1725

 Gln Arg Glu Gly Ser Ser Pro Lys His Gln Asp His Thr Thr Asp
                1730                1735                1740

 Pro Lys Leu Leu Thr Cys Leu Gly Gln Asn Leu His Ser Pro Asp
                1745                1750                1755

 Leu Ala Arg Pro Arg Cys Pro Leu Pro Pro Glu Ala Ser Pro Ser
                1760                1765                1770

 Arg Glu Lys Pro Gly Leu Arg Glu Ser Ser Glu Arg Gly Pro Pro
                1775                1780                1785

 Thr Ala Arg Ser Glu Arg Ser Ala Ala Arg Ala Asp Thr Cys Arg
                1790                1795                1800

 Glu Pro Ser Met Glu Leu Cys Phe Pro Glu Thr Ala Lys Thr Ser
                1805                1810                1815

 Asp Asn Ser Lys Asn Leu Leu Ser Val Gly Arg Thr His Pro Asp
                1820                1825                1830

 Phe Tyr Thr Gln Thr Gln Ala Met Glu Lys Ala Trp Ala Pro Gly
                1835                1840                1845

 Gly Lys Thr Asn His Lys Asp Gly Pro Gly Glu Ala Arg Pro Pro
                1850                1855                1860

 Pro Arg Asp Asn Ser Ser Leu His Ser Ala Gly Ile Pro Cys Glu
                1865                1870                1875

 Lys Glu Leu Gly Lys Val Arg Arg Gly Val Glu Pro Lys Pro Glu
                1880                1885                1890

 Ala Leu Leu Ala Arg Arg Ser Leu Gln Pro Pro Gly Ile Glu Ser
                1895                1900                1905

 Glu Lys Ser Glu Lys Leu Ser Ser Phe Pro Ser Leu Gln Lys Asp
                1910                1915                1920

 Gly Ala Lys Glu Pro Glu Arg Lys Glu Gln Pro Leu Gln Arg His
                1925                1930                1935

 Pro Ser Ser Ile Pro Pro Pro Pro Leu Thr Ala Lys Asp Leu Ser
                1940                1945                1950

 Ser Pro Ala Ala Arg Gln His Cys Ser Ser Pro Ser His Ala Ser
                1955                1960                1965

 Gly Arg Glu Pro Gly Ala Lys Pro Ser Thr Ala Glu Pro Ser Ser
                1970                1975                1980

 Ser Pro Gln Asp Pro Pro Lys Pro Val Ala Ala His Ser Glu Ser
                1985                1990                1995

 Ser Ser His Lys Pro Arg Pro Gly Pro Asp Pro Gly Pro Pro Lys
                2000                2005                2010

 Thr Lys His Pro Asp Arg Ser Leu Ser Ser Gln Lys Pro Ser Val
                2015                2020                2025

 Gly Ala Thr Lys Gly Lys Glu Pro Ala Thr Gln Ser Leu Gly Gly
                2030                2035                2040

 Ser Ser Arg Glu Gly Lys Gly His Ser Lys Ser Gly Pro Asp Val
                2045                2050                2055

 Phe Pro Ala Thr Pro Gly Ser Gln Asn Lys Ala Ser Asp Gly Ile
                2060                2065                2070

 Gly Gln Gly Glu Gly Gly Pro Ser Val Pro Leu His Thr Asp Arg
                2075                2080                2085

 Ala Pro Leu Asp Ala Lys Pro Gln Pro Thr Ser Gly Gly Arg Pro
                2090                2095                2100

 Leu Glu Val Leu Glu Lys Pro Val His Leu Pro Arg Pro Gly His
                2105                2110                2115

 Pro Gly Pro Ser Glu Pro Ala Asp Gln Lys Leu Ser Ala Val Gly
                2120                2125                2130

 Glu Lys Gln Thr Leu Ser Pro Lys His Pro Lys Pro Ser Thr Val
                2135                2140                2145

 Lys Asp Cys Pro Thr Leu Cys Lys Gln Thr Asp Asn Arg Gln Thr
                2150                2155                2160

 Asp Lys Ser Pro Ser Gln Pro Ala Ala Asn Thr Asp Arg Arg Ala
                2165                2170                2175

 Glu Gly Lys Lys Cys Thr Glu Ala Leu Tyr Ala Pro Ala Glu Gly
                2180                2185                2190

 Asp Lys Leu Glu Ala Gly Leu Ser Phe Val His Ser Glu Asn Arg
                2195                2200                2205

 Leu Lys Gly Ala Glu Arg Pro Ala Ala Gly Val Gly Lys Gly Phe
                2210                2215                2220

 Pro Glu Ala Arg Gly Lys Gly Pro Gly Pro Gln Lys Pro Pro Thr
                2225                2230                2235

 Glu Ala Asp Lys Pro Asn Gly Met Lys Arg Ser Pro Ser Ala Thr
                2240                2245                2250

 Gly Gln Ser Ser Phe Arg Ser Thr Ala Leu Pro Glu Lys Ser Leu
                2255                2260                2265

 Ser Cys Ser Ser Ser Phe Pro Glu Thr Arg Ala Gly Val Arg Glu
                2270                2275                2280

 Ala Ser Ala Ala Ser Ser Asp Thr Ser Ser Ala Lys Ala Ala Gly
                2285                2290                2295

 Gly Met Leu Glu Leu Pro Ala Pro Ser Asn Arg Asp His Arg Lys
                2300                2305                2310

 Ala Gln Pro Ala Gly Glu Gly Arg Thr His Met Thr Lys Ser Asp
                2315                2320                2325

 Ser Leu Pro Ser Phe Arg Val Ser Thr Leu Pro Leu Glu Ser His
                2330                2335                2340

 His Pro Asp Pro Asn Thr Met Gly Gly Ala Ser His Arg Asp Arg
                2345                2350                2355

 Ala Leu Ser Val Thr Ala Thr Val Gly Glu Thr Lys Gly Lys Asp
                2360                2365                2370

 Pro Ala Pro Ala Gln Pro Pro Pro Ala Arg Lys Gln Asn Val Gly
                2375                2380                2385

 Arg Asp Val Thr Lys Pro Ser Pro Ala Pro Asn Thr Asp Arg Pro
                2390                2395                2400

 Ile Ser Leu Ser Asn Glu Lys Asp Phe Val Val Arg Gln Arg Arg
                2405                2410                2415

 Gly Lys Glu Ser Leu Arg Ser Ser Pro His Lys Lys Ala Leu
                2420                2425

<210> 4216
<211> 2648
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 571-602
<223> Unknown base

<400> 4216
 aagtaagaat tataaatcta tctcagttaa aagtaggatc tttgttttta 50

 ttcagatatt ttgaaagttt agaagcattt tgtatgctac tttggtattt 100

 cttaagtata gtcagcagga aagggtaacc tgttttatgc aaaatttttt 150

 taatttgtca aatgttttta gtgtgtctac tttctgaaat agtctcaata 200

 tcctgtctgt atcctaggca gataactaca caagaacaaa acgctatata 250

 gaaaagaaaa tatttgagga aatcttaaat tccataagaa agtaattctt 300

 gcaagaatgt tggctacata tttttttttc tgtcctgaat aaattacatc 350

 attaggtctg ttgaagcttt tgaagctacc actattcttt ctgggataaa 400

 ggctaattac tgatttatct gccctcaaaa tcccagagtt aattctaatt 450

 gagtactaaa ttaacagtaa gtagttaaca cagagaacta aaatttaacc 500

 gcattatatc actgtatata tttctcatga tttttgctaa ttagagcatt 550

 tacttaacca gtaataaact nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nngtgtgtgt gtgtatatac ttggctctga cacaactctg gtgcttaatt 650

 aggatatgtt ctattatgta ttttgaatgt ttatcctgct agtgcgatga 700

 acttttgttg gaaaagcaga attagaagga acagtttttc aatcagtttc 750

 atttggtaat tacaggaaaa ccttgagttg ctctaattta atttttccaa 800

 ttaatacatt tagactttaa attgcatccg taattctctt ggctgaaaaa 850

 cagtggtatt ttaagacagt tttgttatac atgtgactta cttttgactc 900

 agcctgagag gaggaaatgt aaagagataa gagatttggc ccaaagcagc 950

 aagagactag taaccttgag ccaggacgaa gccaagacaa cgtgactccc 1000

 aagtagcagg agcagaggtc ggtcacctgt ggcattctgt ttcattccct 1050

 tttaaaatta tgagacttta taggcagtgt aaaacatcag caggcagcga 1100

 tgtgatagga tgtgcgaaaa agctggtctg ataccatggc tataattaca 1150

 gagctttagt tcaattagga ttttgtaaat gagcaaatga cctttttttc 1200

 cagtgcccct tgtaatagtt aatatgagtc catgcaatct tgtgatgcca 1250

 ttctcctgaa ggtgttgatt tctggtaccc agccagctta gctttggctg 1300

 ctggaagcac agtaggtact gatgattact tcctggaaat cttgacaggc 1350

 ttattgtact gtgtaatggg gaaaagttaa agtataatgt ttggtgttaa 1400

 taaatgactg atgtgaaaat aggaacatgt gtctttaata tcaaatatgg 1450

 ctttatttgc agtgaaatct aaattcctta ttctacagta gtattttctt 1500

 gccctgtgtt gtatattttc ctaaatacat ttttcctgac agtggcttta 1550

 ggccagttga acacacttag actgaaagtg tttaacttaa agagatcagt 1600

 ccagaaacca tgataaatta gaatctttat ctggaattac caaattaaaa 1650

 tttaaaatca tggtccagaa gagaacaaac attcatggtt ttttttatcc 1700

 tactgctcat ttttaggtct gtgtttacat ctagtctcta ctatttgtga 1750

 agtatgtcat tatttttttc aagttcttct ttgacttaac tgaaaaataa 1800

 tattccaaat tcttaatgta acatgaaaag agaaatacaa tttttgctta 1850

 aaagacattt tttaaaaagc gttcaattca gtaatcattt ctgttaatac 1900

 aggaagtttt tttggcttgc cagttatata ctgtgggtat tttttaaaat 1950

 gtgctaccct tgggttgtct catatcacct tgcgtaatca tgtattacaa 2000

 aggttgataa ttgtcatttc tcagatgtct gtatgttaca ttggcagcag 2050

 taaaatgttt taatgttgtt accttttaaa taattgtgtt gtattaacat 2100

 gcctcatatt ttctggggaa acttgaaata tatctaaaca aaaaaggtct 2150

 gttataaata ggaattggca tttcattgtt aatgtttttt cctcataaaa 2200

 atagttacac caaaagtgac atattgtcta ttacatgggc ccaatcagta 2250

 ttaaagtact ccccttactc aaaaatatta aaaaataatt catgacactt 2300

 agtagcattt tcattgattg tttcaaaaga tcttcataat ggtcaaattg 2350

 tccaattcac aaaagagtga gaaagttgtt ttcagtactg ggaattttta 2400

 aaccttagtt ttaagaccaa aaatatctct tattagcttg aacattttgt 2450

 gattactttt ccctccccgg atctagtcct tttaaggagt aagtctaaag 2500

 aatgaggcca tgaagtcact atttcctccc acctcagttt gtctcctggt 2550

 acttagctgg cctatcgctt tgtgtggcaa tacccctggg tcgcttcccc 2600

 actcagcctt ctgtatctgc tgttcacagg acatgccatt atgtcttt 2648

<210> 4217
<211> 45
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 571-602
<223> Unknown amino acid

<400> 4217
 Met Lys Ser Leu Phe Pro Pro Thr Ser Val Cys Leu Leu Val Leu
   1               5                  10                  15

 Ser Trp Pro Ile Ala Leu Cys Gly Asn Thr Pro Gly Ser Leu Pro
                  20                  25                  30

 His Ser Ala Phe Cys Ile Cys Cys Ser Gln Asp Met Pro Leu Cys
                  35                  40                  45

<210> 4218
<211> 4659
<212> DNA
<213> Homo sapien

<400> 4218
 gaactctgca tcccctaaga gtcctctgtt cctcccatgt caggtggctc 50

 tcagagtaca gggaccttgg caggtggaga ggaggatggg gagcagcagc 100

 tgggcagccc ccagggctcc tcctccagtg agctcacatc agagcacctc 150

 acagagcaat agccgtcctc agatgctcag caaagttgtg gcagtttgca 200

 tttctagggt aaactaacta ggaaggatgt cgtgaaatgg actatgcaag 250

 agtaagtttg tgtgtttcgc cttaatctga ggcagagaca cagcagaacc 300

 tgaggacaaa agcaggtgga aggtgacggt tagatggtaa gccatgggct 350

 tgtcctggaa ctgcttcaac tcagtggctt aaaatgagaa ctgcccaggt 400

 gagcatggag catctcctag gctcgaggac atctctggag aatcatctgg 450

 aaggtttata ctgtgccttc ccctcgtagc aaaaagattg ttcatggcct 500

 ttaaggaagg ctgagatcac tcacacacag cgccccccca ccccagagaa 550

 accgagtcag cctacatgac ttccaaggga acctggggcc agataagccc 600

 tgccccggtg agaccaaatg agctggagca tgtatggagg tgcggaccct 650

 gcaatcagtt tgcgagtgtg gaggacccga gacatcctgt aaaggcaact 700

 tggtctccct cccactcacc tgccaacatt gctgcaatac acatggttta 750

 tctgaaattc cagggccaga gtgcacatca gctcacatga ctggcaactc 800

 taaatagaga gccctaatgg actgaggcag gaaacgtcta aaagctcaat 850

 ctgctgtatg tcatgacccc ttaggttggg tttatgccac atcggtcatt 900

 ttgaagtagg tgtttgatgc cagctcagag actgtctcag gagtgcctcc 950

 ctggcctggg tagctaccct ggaggtcatc tccctgttct ctgttggata 1000

 aaggaacctc ccccatctgt gacattccct tgggcccagg cttatgacct 1050

 gcaccttttc tgacacctgc ccccaaagca caggatgtga attggtctct 1100

 ctccagatac cccacgagga agcaccttgg acattctgca catgataata 1150

 atgcaacaga gtcccccatt gctgagagat actaacccgt gagaaacaag 1200

 tatgctctca gctggtattg aactggtggg agaaactgcc tcctactttt 1250

 ataatactga attattcaca aaaaacctgg tctgctctcc aaaatgagag 1300

 catgttcctg ggagccacat ggggaccatc cccagctgcc tgctcctggt 1350

 acctccccca tgatcatgca cagaccgtag agtcgagtca tctcgcagat 1400

 ccagaccatc tcctctcatt ctcactctaa aaatgctggt ggcccgcaca 1450

 tgacagcaac tccccgaagc cttccctttg gaatcccata gaatgttctg 1500

 caatgattgg gtccatcttg ctgctcagaa gaatcccgtc ctgctctcta 1550

 gtgtggtggg atgaacttca ggcaacaaac aactggcagg gttcccagtt 1600

 cctggagtta tggagcagaa acacccaggc ctagcagaat tgtggctgaa 1650

 acctggtgcc caaattccac accctggaaa tgtgtcaact gcccgtcagc 1700

 ctggattcaa ttctgagggc taagccacga ccttatccat gagtggcgaa 1750

 gacacccctg agtaaaggat tgcttgcacc tcacatctgt cttcttctaa 1800

 gattactcgg agattttcaa acaacatctg agaacagaag ccccctcccc 1850

 tactcagaga ggaacgaggg tggcccacct ctcaagggcc ttggattcct 1900

 gggaccaccc tttgctggga ggaagaatcc acaccgaatc cttctgtctt 1950

 catggcctgc tgtgctgaaa cagaacagca ggttccatct ttcacatctt 2000

 tttttctccc ccagatgaaa gacgactcag gaacggtagg gctgggcaga 2050

 ggtgtctctc cttgagagac aacaaaagct tctaagggag ggagcttaaa 2100

 ggctgctaga aacctagccc aaccatccac tcctgatctg agacagaacc 2150

 ttctccgcca ctcttcctgc aatcagtgtg aaattccagc ttctttgatt 2200

 cccacttagc agtatgctcc aatcacgttg ctggcaaggc attttagagt 2250

 ttggagctga ggttcaaagc cccctgcatt tctctactgg caggccctgg 2300

 tgaaggaaga cactttcagg gaagaggctc ttacagtcta tggtggtagc 2350

 catcttcaca tccagtcacc agttgcatct agggagctgc tggctataaa 2400

 agggatcatc cagtggagtt gtaaacaagg gaaccatctt gcaagatcta 2450

 ggaagaggaa ggggagggat gtggactggg tctgatcaca gcccttggcc 2500

 ctgcttcata ctttggagct tattaagatc aattttgata accatgtaat 2550

 ttcttagaac catggcaggt agtattgtgc tttaaaaacc agaggctcct 2600

 gaaagtcgtt tacaccaggt gcattgatac catggctgta gctgatgcaa 2650

 ctaacaagta ctggggccag tgatcacaat ccagggttgg aaacaggagt 2700

 gaagcccacc agcctgcctg gttgatggac agcaggctct gccttctgga 2750

 ggcggcttat atcccaacag cctgaggcag ggctctgtgg cccaggccgg 2800

 cagtggctgc ctctcttggt tctgcatggt acattttgcc aaccctgagg 2850

 accagttctt ggggttccag gcctcggcct tcctgctcca cgtgctcaag 2900

 cccccacagg gggctgcgac accatctggc tcctcacagg gaggtccagc 2950

 catgttctct gggctcccag tgagccccct gccctccagc tacccccaga 3000

 atccatcctt cattcctcca ccaagctcct gtgtgagctg cagcacccac 3050

 acgggggaag ccctgcactc cagcagcatc ttccagcctt ggcacagaac 3100

 tgatggcaaa ggaagggctg ggttttcagc ttctgggacc cgaggaagac 3150

 cccacctcac tcctccttcc ccagtacatc agactggtta ggaggcatcc 3200

 cagaaggggc agcctcatgc ccaggtttca gccctaaagg taatgattgt 3250

 cttgactctg ccttggcatt tcgctcggaa tcacggcaga cttggagtgt 3300

 ttcttcaagg caggcatctg cttatgagca aggtcaaaga tttttcaaaa 3350

 tattgtgcat taattcatta aagctactgt taaatatttg ctgtttttag 3400

 attggcgtcc gtgctaattc tgcagttgta gcactgtata ttttatctca 3450

 tttctgtgcc aagaaagttc atctttatgt ttttctaata cacaatcttg 3500

 atcttgtttc caaaataaag cttcagctcc ttggtcaata gaagtaaggg 3550

 tgtagccatc cagggtctcc cggctctagg cagaccggat cccgcagttc 3600

 atcccatggt tgttgaaatg tacctcgatc agtcatctct ggtattcctc 3650

 actctagcca tgagccattg ccatcttatg ggcccgattt gggtactctg 3700

 aattatgtca tggagtagac agttacttct aaatcccagc aaccaagttg 3750

 cgtatccttc cttatagcta gtttctatag agaagtgaaa aagaaatctg 3800

 gcttccttaa taagatagtt gagcctatga cattaaggag cagcgctgct 3850

 ggccgaagat tctagattca ctggtggttt aagaggccca gggatttagt 3900

 tcttactggt gcgtaagtgt tttcccatcc taaccggaaa accactcacc 3950

 caggcttccc ccacttcccc tcaaattttc tcagctctgc cgctggtctc 4000

 catgaacggc aaggggaacc accactcatt cactgtcagt gtaggtaaga 4050

 cagaggatgc ccttgcaaaa attgggactg aggacagtag cacacggaat 4100

 ggtggatcgt acatttgcac ccagagctac taaacgctca gtgaccccag 4150

 agaccattaa tttcccggag tgaaggggat gggggtagag ctaattggaa 4200

 tttttattat caggactcat cctaagaaga atgttggcct ctcttcatcc 4250

 ctggcttagc cgtcaggtag aacgcttact cacctgacac cgacttctta 4300

 gagaagcgag ttttttttga atggaggagc gatggtaacc ccactagggg 4350

 gcgcccatga tcggctccca gtgcaccccc ttaagggtaa gcaggccaca 4400

 tatctagagt ctgatagtct gtgtgtacat aaggtctaga agtctgtgga 4450

 aacgccctga aacctgtagt attatcttaa ctaccctctt atgttaaggt 4500

 ttacataata ggatttttaa acaaatgtgt ttaatttttt aagatctctt 4550

 gtattaaaat tttcttttgg aataagctgt ggaaattttg ttacaacctg 4600

 gttgagatca acctctttac aatgacacaa attgtgacat tttataaatt 4650

 agatacttc 4659

<210> 4219
<211> 3780
<212> DNA
<213> Homo sapien

<400> 4219
 tactggacaa acatttcctc caaggacaca gctctctgcc tccatgtcac 50

 cacctttgaa ggactgactg attccctcgg ctggtgccag tgcctgctcc 100

 tgccatgggg cccgcgggga gcctgctggg cagcggacag atgcagatca 150

 ccctgtgggg aagtctggca gctgtcgcca ttttcttcgt catcaccttc 200

 ctcatcttcc cgtgctctag ttgtgacagg gaaaagaagc cgcgacagca 250

 tagtggggac catgagaacc tgatgaacgt gccttcagac aaggagatgt 300

 tcagccgttc agttactagc ctggcaacag atgctcctgc cagcagtgag 350

 cagaatgggg cactcaccaa tggggacatt ctttcagagg acagtactct 400

 gacctgcatg cagcattacg aggaagtcca gacatcggcc tcggatctgc 450

 tggattccca ggacagcaca gggaaaccaa aatgtcatca gagtcgggag 500

 ctgcccagaa tccctcccga gagcgcagtg gataccatgc tcacggcgag 550

 aagtgtggac ggggaccagg ggctggggat ggaagggccc tatgaagtgc 600

 tcaaggacag ctcctcccaa gaaaacatgg tggaggactg cttgtatgaa 650

 actgtgaagg agatcaagga ggtggctgca gctgcacacc tggagaaagg 700

 ccacagtggc aaggcaaaat ctacttctgc ctcgaaagag ctcccagggc 750

 cccagactga aggcaaagct gagtttgctg aatatgcctc ggtggacaga 800

 aacaaaaaat gtcgtcaaag tgttaatgta gagagtatcc ttggaaattc 850

 atgtgatcca gaagaggagg ccccaccacc tgtccctgtt aagcttctgg 900

 acgagaatga aaaccttcag gagaaggaag ggggagaggc ggaagagagt 950

 gccacagaca cgaccagtga aactaacaag agatttagct cattgtcata 1000

 caagtctcgg gaagaagacc ccactctcac agaagaagag atctcagcta 1050

 tgtactcatc agtaaataaa cctggacagt tagtgaataa atcggggcag 1100

 tcgcttacag ttccggagtc cacctacacc tccattcaag gggacccaca 1150

 gaggtcaccc tcctcctgta atgatctcta tgctactgtt aaagacttcg 1200

 aaaaaactcc aaacagcaca cttccaccag cagggaggcc cagcgaggag 1250

 ccagagcctg attatgaagc gatacagact ctcaacagag aggaagaaaa 1300

 ggccaccctg gggaccaatg gccaccacgg tctcgtccca aaggagaacg 1350

 actacgagag cataagtgac ttgcagcaag gcagagatat taccaggctc 1400

 tagcaaccca gaagacaacc ctgggtagcc tgtgatcagt gtctggagac 1450

 gtttcttctg tggaagagaa gaagtgacac aaacctatac ttcatatgct 1500

 gctttagtca cctgaagatg gttggagagg ccctgtcgac tgttctccca 1550

 gttgttcagt ttctgagaca gagaggtacg gactaggctg cacctgagtg 1600

 tgcccctgcc tgccagatgg acaggtacac ccaagcacat ctccctgctg 1650

 caccctcacc acccacaaaa gatcccagct gtcagtggtc tcatctcatt 1700

 agtgaggaaa gccaagctgt atggaaaagc tgcactcacc aaggaccaca 1750

 atgcccccgg cctaaagtac tgccattcag aaaagcaggt ttttcttcct 1800

 ctctttcctt ttctctgtct gctactgact ttaaggcttt ttcccccttg 1850

 aaatgtccag attcctgtgg ttcatcccaa ggaaattttc acacaaagct 1900

 tggcctttgc cctcaatata ggtgttttag gatggtgaca aaccatggct 1950

 gctgctttct gcccagctcg ccagtcctcc ccaaagagtt gcgcatcagc 2000

 acctggggat ctggaccctg cgggtgaagg gatggggagg gacgtccctg 2050

 gagtctcttc tgtctttgtt ccttcttatt ttggcattcg atatcagcag 2100

 cctctcccca aagtacttga agtcagtttt agatgcttta ttttattttt 2150

 ctagtcaaaa acgtgtttcc cccagtgttt gaaaactcgt ccgaatcttt 2200

 tcagtatttt ccatgagtat tgtggtactt ctagacttgt ttaagcccag 2250

 aactcattcc ttcaaaacag agagccttaa tctttatgtt gggacacaga 2300

 ccacatattt ggacggcagc catgcatcca tcgctgaagg gctgtggaca 2350

 tgaatgtgta tttcccatgg tctccgctgc ccacaccaac agtgtggcat 2400

 ctcataagtt aactgctacc ctaaggtaat ctaagattaa aatgtaaaca 2450

 tttatttttg ttatgtaagt ttataagatg ttttatgttc aatgcctaat 2500

 ttctcaaaag tgccagaaaa aaatgtatat tagctatttt gattttatgt 2550

 acaatgattt atactctcct tttgaaaaga taccataaag cacataagct 2600

 agatcactac aaggagctgt tatctttttt ctaatcaagt gtttaaaaca 2650

 ctgatggttt ttaaagactc acctttttaa atggtacttg gagctcctga 2700

 ttcaaattac ctagaccccc tagagaaata aatggaatat acataaataa 2750

 tcattttcag tggtttatgg tgggcaatat tgcaatattt gaaatggtaa 2800

 aaatggaaag aagaacaaaa tatgatgaga ggtggctgtg aattataaac 2850

 ctcataaaag tgtcataatt ccattaaggt ttaattatat tttttcagaa 2900

 aacagtgatg aattctgtag tccagtgctt gccaatgcaa attgcctatt 2950

 ggaatcttct tcctatattt tacaaacatc agtggctgaa atagctcaga 3000

 gtaagagctc agcctggttt gaatttaatc atctctttag atcttataag 3050

 gccagcatta ggaaacttgt tcacttttca ttttcaaagg agcctagttg 3100

 aagtgctatt atgagtgtgg gctatggaaa gacagctttt cctacactga 3150

 taaagaaaaa aaatgaggaa attatttcat ccccttgtga catctgtgac 3200

 tttttggatt taataatctt gctgtttttc ctctttatga caaagaatat 3250

 aattgggagg atgaagtgtc ttaaaaattg tagagaccag ctcactggaa 3300

 tgtttttcca tccctgtatt catggcttga ctttgtgact gctctacact 3350

 gcatgtctga cattgcagag tgagctatgt tgaggtaaac tggttggttg 3400

 tcattatttt gcaatcagcc tggtctctcc catgaagatg tcgtgtgcat 3450

 aagcacaatc atcactgatt agaagatcac agcagaatac ccttggatta 3500

 gagagaagtt cgtaccttgc atttctctga attctagtct ctcataagca 3550

 ctgctttgct ggatgatttt cactgctttg tgttaatgac tttgagcgat 3600

 ctctcacatg atggggttct ttagtacatg gtaacagcca tgtcatctta 3650

 cacacctagc attgtgaatg ctgtagtgac atcctttata ggcaccttac 3700

 agctcaaaac ttttgtttca tttcatgcct tacttatcaa aaaggcagga 3750

 aagtaggtat gatctctaaa gtaaaaaaaa 3780

<210> 4220
<211> 432
<212> PRT
<213> Homo sapien

<400> 4220
 Met Gly Pro Ala Gly Ser Leu Leu Gly Ser Gly Gln Met Gln Ile
   1               5                  10                  15

 Thr Leu Trp Gly Ser Leu Ala Ala Val Ala Ile Phe Phe Val Ile
                  20                  25                  30

 Thr Phe Leu Ile Phe Pro Cys Ser Ser Cys Asp Arg Glu Lys Lys
                  35                  40                  45

 Pro Arg Gln His Ser Gly Asp His Glu Asn Leu Met Asn Val Pro
                  50                  55                  60

 Ser Asp Lys Glu Met Phe Ser Arg Ser Val Thr Ser Leu Ala Thr
                  65                  70                  75

 Asp Ala Pro Ala Ser Ser Glu Gln Asn Gly Ala Leu Thr Asn Gly
                  80                  85                  90

 Asp Ile Leu Ser Glu Asp Ser Thr Leu Thr Cys Met Gln His Tyr
                  95                 100                 105

 Glu Glu Val Gln Thr Ser Ala Ser Asp Leu Leu Asp Ser Gln Asp
                 110                 115                 120

 Ser Thr Gly Lys Pro Lys Cys His Gln Ser Arg Glu Leu Pro Arg
                 125                 130                 135

 Ile Pro Pro Glu Ser Ala Val Asp Thr Met Leu Thr Ala Arg Ser
                 140                 145                 150

 Val Asp Gly Asp Gln Gly Leu Gly Met Glu Gly Pro Tyr Glu Val
                 155                 160                 165

 Leu Lys Asp Ser Ser Ser Gln Glu Asn Met Val Glu Asp Cys Leu
                 170                 175                 180

 Tyr Glu Thr Val Lys Glu Ile Lys Glu Val Ala Ala Ala Ala His
                 185                 190                 195

 Leu Glu Lys Gly His Ser Gly Lys Ala Lys Ser Thr Ser Ala Ser
                 200                 205                 210

 Lys Glu Leu Pro Gly Pro Gln Thr Glu Gly Lys Ala Glu Phe Ala
                 215                 220                 225

 Glu Tyr Ala Ser Val Asp Arg Asn Lys Lys Cys Arg Gln Ser Val
                 230                 235                 240

 Asn Val Glu Ser Ile Leu Gly Asn Ser Cys Asp Pro Glu Glu Glu
                 245                 250                 255

 Ala Pro Pro Pro Val Pro Val Lys Leu Leu Asp Glu Asn Glu Asn
                 260                 265                 270

 Leu Gln Glu Lys Glu Gly Gly Glu Ala Glu Glu Ser Ala Thr Asp
                 275                 280                 285

 Thr Thr Ser Glu Thr Asn Lys Arg Phe Ser Ser Leu Ser Tyr Lys
                 290                 295                 300

 Ser Arg Glu Glu Asp Pro Thr Leu Thr Glu Glu Glu Ile Ser Ala
                 305                 310                 315

 Met Tyr Ser Ser Val Asn Lys Pro Gly Gln Leu Val Asn Lys Ser
                 320                 325                 330

 Gly Gln Ser Leu Thr Val Pro Glu Ser Thr Tyr Thr Ser Ile Gln
                 335                 340                 345

 Gly Asp Pro Gln Arg Ser Pro Ser Ser Cys Asn Asp Leu Tyr Ala
                 350                 355                 360

 Thr Val Lys Asp Phe Glu Lys Thr Pro Asn Ser Thr Leu Pro Pro
                 365                 370                 375

 Ala Gly Arg Pro Ser Glu Glu Pro Glu Pro Asp Tyr Glu Ala Ile
                 380                 385                 390

 Gln Thr Leu Asn Arg Glu Glu Glu Lys Ala Thr Leu Gly Thr Asn
                 395                 400                 405

 Gly His His Gly Leu Val Pro Lys Glu Asn Asp Tyr Glu Ser Ile
                 410                 415                 420

 Ser Asp Leu Gln Gln Gly Arg Asp Ile Thr Arg Leu
                 425                 430

<210> 4221
<211> 5851
<212> DNA
<213> Homo sapien

<400> 4221
 gtcagcggcg gcggcggcgg cggcagcggg gccgggccgg ggccaggcgc 50

 tgggggggcc agggccggag ctggagccgg agccggagct ggaggcgggc 100

 aaaaccggag cggccggggg cggccacggt gatgagccgg gcctggcgga 150

 cgcggcgcca tcgcagtcag aaggaagagg cccagcagaa gggactcgct 200

 gagccacccc ccgccccact ccatgttggc tgtgctctca ggctggcacc 250

 atgccccccc ctgcagaggt gacggacccg tcccatgccc ccgccgtcct 300

 gcgccagctc aatgaacagc ggctccgtgg cctcttctgt gacgtcaccc 350

 tcatagccgg agacaccaag ttccctgctc accgcagcgt cctggctgct 400

 tcaagtccct tcttcagaga ggccctgctc acttcagccc cactacccct 450

 tccaccagct actgggggcg ccgcacccaa ccctgccacc accacagctg 500

 cctcttcctc ctcctcctct tcctcgtctt cttcctcttc ttcctcctct 550

 gcttcttctt cttcttcctc ttcctcttcc tctccccctc cagcctctcc 600

 ccctgcttct tccccacccc gggtcctgga gttgccagga gtcccagcag 650

 ctgcgttttc tgatgtcctc aacttcatct acagcgcccg gctcgcactg 700

 cctggtggtg gaggggacgg ggcagctgta gcagagattg gagctttggg 750

 gcgccgtctg ggcatctccc gccttcaggg cctgggggag ggaggtgatg 800

 cctgggtacc tcctacccca gcccccatgg ccacctcgca gcctgaagag 850

 gacagctttg ggcccgggcc caggccagct ggggagtggg agggtgacag 900

 ggctgaggcc caggcccctg acttgcagtg ctccctgccc cggcggcccc 950

 tcccctgccc ccagtgtgga aaaagcttca tccatcccaa acggctgcag 1000

 acccatgagg cccagtgccg acgaggggcc agcacgcggg ggtctacagg 1050

 gctgggagct gggggcgctg gccctggtgg tcctgcaggg gtggacgcct 1100

 cagccctgcc tccaccagtg ggcttccgag ggggccccga gcacgtggtg 1150

 aaggtggtgg gcggccacgt gctgtatgtg tgcgcggcct gcgagcgttc 1200

 ctacgtgacc ctgtccagtc tgaagagaca cagcaatgta cactcgtggc 1250

 ggaggaagta cccctgccgc tattgtgaga aagtgtttgc tctggcggag 1300

 taccgcacga agcatgaagt gtggcacacg ggggagcgca ggtaccagtg 1350

 catcttctgt tgggagacct ttgtcactta ctataacctg aagacccacc 1400

 agcgagcctt ccacggcatt agcccgggcc tccttgccag tgagaagaca 1450

 cccaatggag gctacaagcc caagctcaat acactcaagc tctaccgcct 1500

 gctccccatg cgggcagcca agcggcccta caagacctac agccagggag 1550

 ccccggaggc tcccctttct ccaaccctca acacaccggc ccctgtggca 1600

 atgccagcca gcccgccgcc tgggcctcca cctgccccag agcctggccc 1650

 tccaccctct gtcatcactt ttgcccaccc agccccctct gtcattgtcc 1700

 atgggggcag tagcagtggt ggagggggga gtgggacggc cagcacagga 1750

 gggtcccaag ctgcctcggt tatcacttac actgctcccc cgaggccacc 1800

 caagaaacga gaatacccac ctcctccccc tgagcctgca gccacaccca 1850

 ccagcccagc cacagcagtc agcccagcca ccgctgcagg gccagccatg 1900

 gccaccacca cggaggaggc caagggccgg aatccacggg ctggaaggac 1950

 tctgacttac acagccaagc cagtgggcgg gattggtgga ggtgggggtc 2000

 cccccacagg ggctggccgg ggcccctctc agctgcaggc tccacctcca 2050

 ctgtgtcaga tcactgtgcg aataggggag gaggccatcg tcaagcgccg 2100

 catctcagag actgacctgc gtcctgggga gctgagcgga gaggagatgg 2150

 aggagagtga ggaggacgaa gaggaggagg acgaagagga ggaggaggag 2200

 gatgaggagg aatcaaaggc tggtggggag gaccagctct ggaggcccta 2250

 ctactcctac aagcctaagc gcaaggctgg agctgctgga ggtgccagtg 2300

 tggggggcag tgggctgccc cgaggccgcc ggccaccacg ttggaggcag 2350

 aagctggaac ggaggagctg ggaggaaacc ccagcggccg agagcccagc 2400

 gggacgtgcc cgcacagagc ggaggcaccg atgcggggac tgtgcccaga 2450

 ccttcaccac cctgagaaag ctgcggaagc accaagaggc ccacggtggg 2500

 ggctcccaca gctcccgggc cggacggagg ccctccaccc gctttacctg 2550

 cccccactgc gccaaggtgt gcaagaccgc agctgccctg agccgccacg 2600

 ggcagaggca tgctgctgag cggcccgggg gcaccccaac ccctgtcatt 2650

 gcctattcca agggcagcgc tggcaccagg cccggggatg tcaaggagga 2700

 agccccccaa gagatgcaag tctcctcatc cagcggtgag gcaggtggcg 2750

 ggagcactgc tgctgaggaa gcttccgaga ccgcctcact ccaggaccct 2800

 atcatttcag ggggtgagga gcccccagta gtggcaagcg ggggcagcta 2850

 tgtataccca cctgtgcagg aatttccact ggccttgatt gggggcggcc 2900

 gggaacctgg cggtggcagg ggaaaatctg ggagtgaagg gccagtgggg 2950

 gctggtgagg gggaccggat ggaggggata ggggctgcca aagtcacttt 3000

 ctaccctgag ccctacccgc tcgtctatgg cccccagctc cttgccgcct 3050

 acccttacaa cttcagtaac ttggccgctc tcccggttgc tctcaacatg 3100

 gtcctacctg atgagaaggg tgcgggggcc cttcccttcc taccaggggt 3150

 ctttggctac gcagtgaatc ctcaagcagc accccctgcc ccaccaacac 3200

 cacctccccc aactcttcct ccaccaattc cccctaaggg agaaggggaa 3250

 agggcagggg ttgagagaac ccagaagggc gatgtggggt gaaccctggg 3300

 gctcaatccc cctttcacca gatgccaccc tccctgaacc ccccaccact 3350

 accagctccc tggcctccct gccccttggg agccccttca cactcttgtg 3400

 cagggacttg ggggcccctg gagctcaggg gtcaggctgc tttgtgtgag 3450

 atgtagtttt cccatctcct gggaagggat ctttcgaggt tcccctctca 3500

 gtcttcctcc agggaatggc ctccatgagg ggcagggcca gcttccatcc 3550

 cttctccagc ccttggggca actgagcaat atacttaacc tgaatctcta 3600

 ctcacagccc ccaccagctc tgaatgtcta acctgctccc ctgattcgta 3650

 aacctagggg aaaccatctc tctcacctaa tgacccgcct tgttctgaag 3700

 ctttctctaa gcccttccca gttgcttcct agcacattcc attctttgtg 3750

 gcccagggcc tggaccagac cattgtgata cctgaccccg cccacctggg 3800

 agtgtggctt tgggtttcat ccttccccag cgtgggtctc tacgtccctg 3850

 tttcccttgt atcaagacac cttcctcagc ttccatgcct ttggatcttc 3900

 catgttcctc cccatattcc tggacttcgg agatggcctc tcccaagcca 3950

 ggtcaaggag gtttggggga gggttgcccc tctgcccctc tgttctgtgg 4000

 ctgagcactt tcccagtcca gggcagggaa atattggccc tatcttgacc 4050

 cccaaatcca gtgagctcca gattcttcca aggcaaaaga ggtaagcaga 4100

 tcacacctct ttctgcctct acatatggcc tattctgggc tagaccagat 4150

 ttgggggcca ggagggaaga actccatatg ggatggagaa gggaatctac 4200

 tttctccctg tttttttttc ctgatggttt ctcccagact agaccaaata 4250

 gccagaaaaa tgataggggt cggatgggtg ggtaagccca ggatttgcac 4300

 atgaccttcc atccttacct gtattcccat ctccccagtg tcactcccct 4350

 caccaatcac tccagatggt tttgggggaa ccattctact cttctggtgg 4400

 gctttggggt atccccacca actttccctt caaaatagca ccttacaccc 4450

 catctttgac tcagttcccc acacccaaag atcccagcct agggatgggg 4500

 tacagggact ttaaatagtc cctaatccct aatttgcact agttaaccct 4550

 ggtcagggtc cctgtatttc cttccagtgg gggagataaa tgtttgctcc 4600

 taattctctt tgaaaactgg gcctccctgc tctgtgattg gataaatatt 4650

 tcccatccca cccacctccc cccaaaaaat agctcacaag gggagagcca 4700

 gtatggggga gcaaatttga caaatgggaa ttagaggagt gcagttttaa 4750

 aaggaaaagt tgctgtcatc aaaatggcag ccttttcccc agctactgtt 4800

 tttggggcca agatggctgc cctagcagca atcactgcca agggcaagat 4850

 catggctttt ggagggaggt gagtttaggg agggccagga ccatcctcct 4900

 acccctcata ccctcccagc atatacaaaa ggggaggttt tagacaggct 4950

 ccctgaatgt taaccacaga ggagtcactc cttcattcct cctctgtctc 5000

 tttgcacttt tcttggtctt ggccacagcc tgagtgacga atttcctact 5050

 gaatgtacca agttccaatt tttaaggggg ggaaaggttt caaatgggga 5100

 aaaacacaca aaaaaaaaat cactaaaaat tcccacaaat cttgtttctg 5150

 gcactttaga aaaactgcaa aaaaatacgt aataaagaat acatatatat 5200

 atatctacac acaaattata tatctatcta tctatacagc ggaaccacaa 5250

 gagagactga ggaaggcctg gaggcagggg cagaggtgac gacagtgccc 5300

 ctatatcctt aacccatact cctctgaggc aaacaggcat gggaaaatgg 5350

 aagggttgag gatggaccgg agaattggaa cttcagaata ggtcaaaatt 5400

 ccaaaaccat ggacattttt ttttgggaga attgagattg tagacatttt 5450

 ttttttctta agtatgatca aggaaaatag cttccagaat gtggtggttc 5500

 tgggcaacaa atgagattgt ggcgacgtgg agattaaaat atatgtattt 5550

 gagctgggga atttgaatat tgtgagtttc agatgttgga aatttgggat 5600

 tttgcagttt tgtcttttga aaatgatcaa gtcttgtcag ttcgtgccct 5650

 ctttccccat gttccctggg aagacgggtg gtggcagagt gagaaggcca 5700

 ctggttctgt gccgcagcac gcaaaattta gaattctaca gactagctct 5750

 atacgtagtg aggacccaga tttagagaaa ctgaccaata tttatctccg 5800

 catttgtgtg tgtgtccaac tctgtaggcc aataaaccaa caagacaaat 5850

 g 5851

<210> 4222
<211> 1029
<212> PRT
<213> Homo sapien

<400> 4222
 Ala Thr Pro Arg Pro Thr Pro Cys Trp Leu Cys Ser Gln Ala Gly
   1               5                  10                  15

 Thr Met Pro Pro Pro Ala Glu Val Thr Asp Pro Ser His Ala Pro
                  20                  25                  30

 Ala Val Leu Arg Gln Leu Asn Glu Gln Arg Leu Arg Gly Leu Phe
                  35                  40                  45

 Cys Asp Val Thr Leu Ile Ala Gly Asp Thr Lys Phe Pro Ala His
                  50                  55                  60

 Arg Ser Val Leu Ala Ala Ser Ser Pro Phe Phe Arg Glu Ala Leu
                  65                  70                  75

 Leu Thr Ser Ala Pro Leu Pro Leu Pro Pro Ala Thr Gly Gly Ala
                  80                  85                  90

 Ala Pro Asn Pro Ala Thr Thr Thr Ala Ala Ser Ser Ser Ser Ser
                  95                 100                 105

 Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ala Ser Ser Ser
                 110                 115                 120

 Ser Ser Ser Ser Ser Ser Ser Pro Pro Pro Ala Ser Pro Pro Ala
                 125                 130                 135

 Ser Ser Pro Pro Arg Val Leu Glu Leu Pro Gly Val Pro Ala Ala
                 140                 145                 150

 Ala Phe Ser Asp Val Leu Asn Phe Ile Tyr Ser Ala Arg Leu Ala
                 155                 160                 165

 Leu Pro Gly Gly Gly Gly Asp Gly Ala Ala Val Ala Glu Ile Gly
                 170                 175                 180

 Ala Leu Gly Arg Arg Leu Gly Ile Ser Arg Leu Gln Gly Leu Gly
                 185                 190                 195

 Glu Gly Gly Asp Ala Trp Val Pro Pro Thr Pro Ala Pro Met Ala
                 200                 205                 210

 Thr Ser Gln Pro Glu Glu Asp Ser Phe Gly Pro Gly Pro Arg Pro
                 215                 220                 225

 Ala Gly Glu Trp Glu Gly Asp Arg Ala Glu Ala Gln Ala Pro Asp
                 230                 235                 240

 Leu Gln Cys Ser Leu Pro Arg Arg Pro Leu Pro Cys Pro Gln Cys
                 245                 250                 255

 Gly Lys Ser Phe Ile His Pro Lys Arg Leu Gln Thr His Glu Ala
                 260                 265                 270

 Gln Cys Arg Arg Gly Ala Ser Thr Arg Gly Ser Thr Gly Leu Gly
                 275                 280                 285

 Ala Gly Gly Ala Gly Pro Gly Gly Pro Ala Gly Val Asp Ala Ser
                 290                 295                 300

 Ala Leu Pro Pro Pro Val Gly Phe Arg Gly Gly Pro Glu His Val
                 305                 310                 315

 Val Lys Val Val Gly Gly His Val Leu Tyr Val Cys Ala Ala Cys
                 320                 325                 330

 Glu Arg Ser Tyr Val Thr Leu Ser Ser Leu Lys Arg His Ser Asn
                 335                 340                 345

 Val His Ser Trp Arg Arg Lys Tyr Pro Cys Arg Tyr Cys Glu Lys
                 350                 355                 360

 Val Phe Ala Leu Ala Glu Tyr Arg Thr Lys His Glu Val Trp His
                 365                 370                 375

 Thr Gly Glu Arg Arg Tyr Gln Cys Ile Phe Cys Trp Glu Thr Phe
                 380                 385                 390

 Val Thr Tyr Tyr Asn Leu Lys Thr His Gln Arg Ala Phe His Gly
                 395                 400                 405

 Ile Ser Pro Gly Leu Leu Ala Ser Glu Lys Thr Pro Asn Gly Gly
                 410                 415                 420

 Tyr Lys Pro Lys Leu Asn Thr Leu Lys Leu Tyr Arg Leu Leu Pro
                 425                 430                 435

 Met Arg Ala Ala Lys Arg Pro Tyr Lys Thr Tyr Ser Gln Gly Ala
                 440                 445                 450

 Pro Glu Ala Pro Leu Ser Pro Thr Leu Asn Thr Pro Ala Pro Val
                 455                 460                 465

 Ala Met Pro Ala Ser Pro Pro Pro Gly Pro Pro Pro Ala Pro Glu
                 470                 475                 480

 Pro Gly Pro Pro Pro Ser Val Ile Thr Phe Ala His Pro Ala Pro
                 485                 490                 495

 Ser Val Ile Val His Gly Gly Ser Ser Ser Gly Gly Gly Gly Ser
                 500                 505                 510

 Gly Thr Ala Ser Thr Gly Gly Ser Gln Ala Ala Ser Val Ile Thr
                 515                 520                 525

 Tyr Thr Ala Pro Pro Arg Pro Pro Lys Lys Arg Glu Tyr Pro Pro
                 530                 535                 540

 Pro Pro Pro Glu Pro Ala Ala Thr Pro Thr Ser Pro Ala Thr Ala
                 545                 550                 555

 Val Ser Pro Ala Thr Ala Ala Gly Pro Ala Met Ala Thr Thr Thr
                 560                 565                 570

 Glu Glu Ala Lys Gly Arg Asn Pro Arg Ala Gly Arg Thr Leu Thr
                 575                 580                 585

 Tyr Thr Ala Lys Pro Val Gly Gly Ile Gly Gly Gly Gly Gly Pro
                 590                 595                 600

 Pro Thr Gly Ala Gly Arg Gly Pro Ser Gln Leu Gln Ala Pro Pro
                 605                 610                 615

 Pro Leu Cys Gln Ile Thr Val Arg Ile Gly Glu Glu Ala Ile Val
                 620                 625                 630

 Lys Arg Arg Ile Ser Glu Thr Asp Leu Arg Pro Gly Glu Leu Ser
                 635                 640                 645

 Gly Glu Glu Met Glu Glu Ser Glu Glu Asp Glu Glu Glu Glu Asp
                 650                 655                 660

 Glu Glu Glu Glu Glu Glu Asp Glu Glu Glu Ser Lys Ala Gly Gly
                 665                 670                 675

 Glu Asp Gln Leu Trp Arg Pro Tyr Tyr Ser Tyr Lys Pro Lys Arg
                 680                 685                 690

 Lys Ala Gly Ala Ala Gly Gly Ala Ser Val Gly Gly Ser Gly Leu
                 695                 700                 705

 Pro Arg Gly Arg Arg Pro Pro Arg Trp Arg Gln Lys Leu Glu Arg
                 710                 715                 720

 Arg Ser Trp Glu Glu Thr Pro Ala Ala Glu Ser Pro Ala Gly Arg
                 725                 730                 735

 Ala Arg Thr Glu Arg Arg His Arg Cys Gly Asp Cys Ala Gln Thr
                 740                 745                 750

 Phe Thr Thr Leu Arg Lys Leu Arg Lys His Gln Glu Ala His Gly
                 755                 760                 765

 Gly Gly Ser His Ser Ser Arg Ala Gly Arg Arg Pro Ser Thr Arg
                 770                 775                 780

 Phe Thr Cys Pro His Cys Ala Lys Val Cys Lys Thr Ala Ala Ala
                 785                 790                 795

 Leu Ser Arg His Gly Gln Arg His Ala Ala Glu Arg Pro Gly Gly
                 800                 805                 810

 Thr Pro Thr Pro Val Ile Ala Tyr Ser Lys Gly Ser Ala Gly Thr
                 815                 820                 825

 Arg Pro Gly Asp Val Lys Glu Glu Ala Pro Gln Glu Met Gln Val
                 830                 835                 840

 Ser Ser Ser Ser Gly Glu Ala Gly Gly Gly Ser Thr Ala Ala Glu
                 845                 850                 855

 Glu Ala Ser Glu Thr Ala Ser Leu Gln Asp Pro Ile Ile Ser Gly
                 860                 865                 870

 Gly Glu Glu Pro Pro Val Val Ala Ser Gly Gly Ser Tyr Val Tyr
                 875                 880                 885

 Pro Pro Val Gln Glu Phe Pro Leu Ala Leu Ile Gly Gly Gly Arg
                 890                 895                 900

 Glu Pro Gly Gly Gly Arg Gly Lys Ser Gly Ser Glu Gly Pro Val
                 905                 910                 915

 Gly Ala Gly Glu Gly Asp Arg Met Glu Gly Ile Gly Ala Ala Lys
                 920                 925                 930

 Val Thr Phe Tyr Pro Glu Pro Tyr Pro Leu Val Tyr Gly Pro Gln
                 935                 940                 945

 Leu Leu Ala Ala Tyr Pro Tyr Asn Phe Ser Asn Leu Ala Ala Leu
                 950                 955                 960

 Pro Val Ala Leu Asn Met Val Leu Pro Asp Glu Lys Gly Ala Gly
                 965                 970                 975

 Ala Leu Pro Phe Leu Pro Gly Val Phe Gly Tyr Ala Val Asn Pro
                 980                 985                 990

 Gln Ala Ala Pro Pro Ala Pro Pro Thr Pro Pro Pro Pro Thr Leu
                 995                1000                1005

 Pro Pro Pro Ile Pro Pro Lys Gly Glu Gly Glu Arg Ala Gly Val
                1010                1015                1020

 Glu Arg Thr Gln Lys Gly Asp Val Gly
                1025

<210> 4223
<211> 603
<212> DNA
<213> Homo sapien

<400> 4223
 ggcgatccta ctaaataaac agaatgagga aaattgatga gagtgatacc 50

 acatgttgga aagataaggg agcagctaaa cctctcctta tccttattgc 100

 ttataagaat gtaggcctgg gcgtgagcca ctgttcccag caggaatttc 150

 ttttttatag tattggataa agtttggtgt ttttacagag gagaagcaat 200

 gggtcttagc tctttctcta ttatgttatc atcctccctt ttttgtacaa 250

 tatgttgttt acctgaaagg aaggtttcta ttcgttggtt gtggacctgg 300

 acaaagtcca agtctgtgga acttaaaacc ttgaaggtct gtcataggac 350

 tctggacaat ctcacacctt agctattccc agggaacccc agggggcaac 400

 tgacattgct ccaagatgtt ctcctgatgt agcttgagat ataaaggaaa 450

 ggccctgcac aggtggctgt ttcttgtctg ttatgtcaga ggaacagtcc 500

 tgttcagaaa ggggctcttc tgagcagaaa tggctaataa actttgtgct 550

 gatctgaaaa aaaatctatg tcgggtgcgg agaaagaggt aatgaaatgg 600

 cag 603

<210> 4224
<211> 3
<212> PRT
<213> Homo sapien

<400> 4224
 Met Lys Trp
   1

<210> 4225
<211> 859
<212> DNA
<213> Homo sapien

<400> 4225
 agctatttca aggcgcgcgc ctcgtggtgg actcaccgct agcccgcagc 50

 gctcggcttc ctggtaattc ttcacctctt ttctcagctc cctgcagcat 100

 gggtgctggg ccctccttgc tgctcgccgc cctcctgctg cttctctccg 150

 gcgacggcgc cgtgcgctgc gacacacctg ccaactgcac ctatcttgac 200

 ctgctgggca cctgggtctt ccaggtgggc tccagcggtt cccagcgcga 250

 tgtcaactgc tcggttatgg gaccacaaga aaaaaaagta gtggtgtacc 300

 ttcagaagct ggatacagca tatgatgacc ttggcaattc tggccatttc 350

 accatcattt acaaccaagg ctttgagatt gtgttgaatg actacaagtg 400

 gtttgccttt tttaaggatg tcactgattt tatcagtcat ttgttcatgc 450

 agctgggaac tgtggggata tatgatttgc cacatctgag gaacaaactg 500

 gttattaaat agagcatctg ttgagggact cttttaaaac cacagccatg 550

 aacagacgtt ggggctaaga gacagagcag cctgcgacag tgtggaccta 600

 cctgtagcag ctagcaaagg cctctagcag ctacagtccc ttctggagtc 650

 tttatttgca tgcaaaatgc aaaggagtcc tggtgaccta cctccaaggc 700

 agctgccctc ctgaacactc ccttggaaaa cagtaaacat cattttggaa 750

 tgtgaacaac cagagactac acaggagaaa ggaaaaaaaa attctgaaga 800

 tgcaaaatct tgggtggctt caccgttcag ttttttaata aaaggaacaa 850

 tatacaaca 859

<210> 4226
<211> 137
<212> PRT
<213> Homo sapien

<400> 4226
 Met Gly Ala Gly Pro Ser Leu Leu Leu Ala Ala Leu Leu Leu Leu
   1               5                  10                  15

 Leu Ser Gly Asp Gly Ala Val Arg Cys Asp Thr Pro Ala Asn Cys
                  20                  25                  30

 Thr Tyr Leu Asp Leu Leu Gly Thr Trp Val Phe Gln Val Gly Ser
                  35                  40                  45

 Ser Gly Ser Gln Arg Asp Val Asn Cys Ser Val Met Gly Pro Gln
                  50                  55                  60

 Glu Lys Lys Val Val Val Tyr Leu Gln Lys Leu Asp Thr Ala Tyr
                  65                  70                  75

 Asp Asp Leu Gly Asn Ser Gly His Phe Thr Ile Ile Tyr Asn Gln
                  80                  85                  90

 Gly Phe Glu Ile Val Leu Asn Asp Tyr Lys Trp Phe Ala Phe Phe
                  95                 100                 105

 Lys Asp Val Thr Asp Phe Ile Ser His Leu Phe Met Gln Leu Gly
                 110                 115                 120

 Thr Val Gly Ile Tyr Asp Leu Pro His Leu Arg Asn Lys Leu Val
                 125                 130                 135

 Ile Lys


<210> 4227
<211> 3828
<212> DNA
<213> Homo sapien

<400> 4227
 cgactcctta gagcatggca tggctcagag gtgctggtaa aactgatggg 50

 ggtttttgct gtccctcccc tcagcgccga caccatgtgg atccaggttc 100

 ggaccatgga cgggaggcag acccacacgg tggactcgct gtccaggctg 150

 accaaggtgg aggagctgag gcggaagatc caggagctgt tccacgtgga 200

 gccaggcctg cagaggctgt tctacagggg caaacagatg gaggacggcc 250

 ataccctctt cgactacgag gtccgcctga atgacaccat ccagctcctg 300

 gtccgccaga gcctcgtgct cccccacagc accaaggagc gggactccga 350

 gctctccgac accgactccg gctgctgcct gggccagagt gagtcagaca 400

 agtcctccac ccacggcgag gcggccgccg agactgacag caggccagcc 450

 gatgaggaca tgtgggatga gacggaattg gggctgtaca aggtcaatga 500

 gtacgtcgat gctcgggaca cgaacatggg ggcgtggttt gaggcgcagg 550

 tggtcagggt gacgcggaag gccccctccc gggacgagcc ctgcagctcc 600

 acgtccaggc cggcgctgga ggaggacgtc atttaccacg tgaaatacga 650

 cgactacccg gagaacggcg tggtccagat gaactccagg gacgtccgag 700

 cgcgcgcccg caccatcatc aagtggcagg acctggaggt gggccaggtg 750

 gtcatgctca actacaaccc cgacaacccc aaggagcggg gcttctggta 800

 cgacgcggag atctccagga agcgcgagac caggacggcg cgggaactct 850

 acgccaacgt ggtgctgggg gatgattctc tgaacgactg tcggatcatc 900

 ttcgtggacg aagtcttcaa gattgagcgg ccgggtgaag ggagccccat 950

 ggttgacaac cccatgagac ggaagagcgg gccgtcctgc aagcactgca 1000

 aggacgacgt gaacagactc tgccgggtct gcgcctgcca cctgtgcggg 1050

 ggccggcagg accccgacaa gcagctcatg tgcgatgagt gcgacatggc 1100

 cttccacatc tactgcctgg acccgcccct cagcagtgtt cccagcgagg 1150

 acgagtggta ctgccctgag tgccggaatg atgccagcga ggtggtactg 1200

 gcgggagagc ggctgagaga gagcaagaag aaggcgaaga tggcctcggc 1250

 cacatcgtcc tcacagcggg actggggcaa gggcatggcc tgtgtgggcc 1300

 gcaccaagga atgtaccatc gtcccgtcca accactacgg acccatcccg 1350

 gggatccccg tgggcaccat gtggcggttc cgagtccagg tcagcgagtc 1400

 gggtgtccat cggccccacg tggctggcat acacggccgg agcaacgacg 1450

 gagcgtactc cctagtcctg gcggggggct atgaggatga cgtggaccat 1500

 gggaattttt tcacatacac gggtagtggt ggtcgagatc tttccggcaa 1550

 caagaggacc gcggaacagt cttgtgatca gaaactcacc aacaccaaca 1600

 gggcgctggc tctcaactgc tttgctccca tcaatgacca agaaggggcc 1650

 gaggccaagg actggcggtc ggggaagccg gtcagggtgg tgcgcaatgt 1700

 caagggtggc aagaatagca agtacgcccc cgctgagggc aaccgctacg 1750

 atggcatcta caaggttgtg aaatactggc ccgagaaggg gaagtccggg 1800

 tttctcgtgt ggcgctacct tctgcggagg gacgatgatg agcctggccc 1850

 ttggacgaag gaggggaagg accggatcaa gaagctgggg ctgaccatgc 1900

 agtatccaga aggctacctg gaagccctgg ccaaccgaga gcgagagaag 1950

 gagaacagca agagggagga ggaggagcag caggaggggg gcttcgcgtc 2000

 ccccaggacg ggcaagggca agtggaagcg gaagtcggca ggaggtggcc 2050

 cgagcagggc cgggtccccg cgccggacat ccaagaaaac caaggtggag 2100

 ccctacagtc tcacggccca gcagagcagc ctcatcagag aggacaagag 2150

 caacgccaag ctgtggaatg aggtcctggc gtcactcaag gaccggccgg 2200

 cgagcggcag cccgttccag ttgttcctga gtaaagtgga ggagacgttc 2250

 cagtgtatct gctgtcagga gctggtgttc cggcccatca cgaccgtgtg 2300

 ccagcacaac gtgtgcaagg actgcctgga cagatccttt cgggcacagg 2350

 tgttcagctg ccctgcctgc cgctacgacc tgggccgcag ctatgccatg 2400

 caggtgaacc agcctctgca gaccgtcctc aaccagctct tccccggcta 2450

 cggcaatggc cggtgatctc caagcacttc tcgacaggcg ttttgctgaa 2500

 aacgtgtcgg agggctcgtt catcggcact gattttgttc ttagtgggct 2550

 taacttaaac aggtagtgtt tcctccgttc cctaaaaagg tttgtcttcc 2600

 ttttttttta tttttatttt tcaaatctat acattttcag gaatttatgt 2650

 attctggcta aaagttggac ttctcagtat tgtgtttagt tctttgaaaa 2700

 cataaaagcc tgcaatttct cgacaaaaca acacaagatt ttttaaagat 2750

 ggaatcagaa actacgtggt gtggaggctg ttgatgtttc tggtgtcaag 2800

 ttctcagaag ttgctgccac caactcttta agaaggcgac aggatcagtc 2850

 cttctctagg gttctggccc ccaaggtcag agcaagcatc ttcctgacag 2900

 cattttgtca tctaaagtcc agtgacatgg ttccccgtgg tggcccgtgg 2950

 cagcccgtgg catggcgtgg ctcagctgtc tgttgaagtt gttgcaagga 3000

 aaagaggaaa catctcgggc ctagttcaaa cctttgcctc aaagccatcc 3050

 cccaccagac tgcttagcgt ctgagatccg cgtgaaaagt cctctgccca 3100

 cgagagcagg gagttggggc cacgcagaaa tggcctcaag gggactctgc 3150

 tccacgtggg gccaggcgtg tgactgacgc tgtccgacga aggcggccac 3200

 ggacggacgc cagcacacga agtcacgtgc aagtgccttt gattcgttcc 3250

 ttctttctaa agacgacagt ctttgttgtt agcactgaat tattgaaaat 3300

 gtcaaccaga ttctagaaac tgcggtcatc cagttcttcc tgacaccgga 3350

 tgggtgcttg ggaaccgttt gagccttata gatcatttac attcaatttt 3400

 tttaactcag caagtgagaa cttacaagag ggtttttttt taattttttt 3450

 ttctcttaat gaacacattt tctaaatgaa ttttttttgt agttactgta 3500

 tatgtaccaa gaaagatata acgttagggt ttggttgttt ttgtttttgt 3550

 attttttttc ttttgaaagg gtttgttaat ttttctaatt ttaccaaagt 3600

 ttgcagccta tacctcaata aaacagggat attttaaatc acatacctgc 3650

 agacaaactg gagcaatgtt atttttaaag ggtttttttc acctccttat 3700

 tcttagatta ttaatgtatt agggaagaat gagacaattt tgtgtaggct 3750

 ttttctaaag tccagtactt tgtccagatt ttagattctc agaataaatg 3800

 tttttcacag attgaaaaaa aaaaaaaa 3828

<210> 4228
<211> 793
<212> PRT
<213> Homo sapien

<400> 4228
 Met Trp Ile Gln Val Arg Thr Met Asp Gly Arg Gln Thr His Thr
   1               5                  10                  15

 Val Asp Ser Leu Ser Arg Leu Thr Lys Val Glu Glu Leu Arg Arg
                  20                  25                  30

 Lys Ile Gln Glu Leu Phe His Val Glu Pro Gly Leu Gln Arg Leu
                  35                  40                  45

 Phe Tyr Arg Gly Lys Gln Met Glu Asp Gly His Thr Leu Phe Asp
                  50                  55                  60

 Tyr Glu Val Arg Leu Asn Asp Thr Ile Gln Leu Leu Val Arg Gln
                  65                  70                  75

 Ser Leu Val Leu Pro His Ser Thr Lys Glu Arg Asp Ser Glu Leu
                  80                  85                  90

 Ser Asp Thr Asp Ser Gly Cys Cys Leu Gly Gln Ser Glu Ser Asp
                  95                 100                 105

 Lys Ser Ser Thr His Gly Glu Ala Ala Ala Glu Thr Asp Ser Arg
                 110                 115                 120

 Pro Ala Asp Glu Asp Met Trp Asp Glu Thr Glu Leu Gly Leu Tyr
                 125                 130                 135

 Lys Val Asn Glu Tyr Val Asp Ala Arg Asp Thr Asn Met Gly Ala
                 140                 145                 150

 Trp Phe Glu Ala Gln Val Val Arg Val Thr Arg Lys Ala Pro Ser
                 155                 160                 165

 Arg Asp Glu Pro Cys Ser Ser Thr Ser Arg Pro Ala Leu Glu Glu
                 170                 175                 180

 Asp Val Ile Tyr His Val Lys Tyr Asp Asp Tyr Pro Glu Asn Gly
                 185                 190                 195

 Val Val Gln Met Asn Ser Arg Asp Val Arg Ala Arg Ala Arg Thr
                 200                 205                 210

 Ile Ile Lys Trp Gln Asp Leu Glu Val Gly Gln Val Val Met Leu
                 215                 220                 225

 Asn Tyr Asn Pro Asp Asn Pro Lys Glu Arg Gly Phe Trp Tyr Asp
                 230                 235                 240

 Ala Glu Ile Ser Arg Lys Arg Glu Thr Arg Thr Ala Arg Glu Leu
                 245                 250                 255

 Tyr Ala Asn Val Val Leu Gly Asp Asp Ser Leu Asn Asp Cys Arg
                 260                 265                 270

 Ile Ile Phe Val Asp Glu Val Phe Lys Ile Glu Arg Pro Gly Glu
                 275                 280                 285

 Gly Ser Pro Met Val Asp Asn Pro Met Arg Arg Lys Ser Gly Pro
                 290                 295                 300

 Ser Cys Lys His Cys Lys Asp Asp Val Asn Arg Leu Cys Arg Val
                 305                 310                 315

 Cys Ala Cys His Leu Cys Gly Gly Arg Gln Asp Pro Asp Lys Gln
                 320                 325                 330

 Leu Met Cys Asp Glu Cys Asp Met Ala Phe His Ile Tyr Cys Leu
                 335                 340                 345

 Asp Pro Pro Leu Ser Ser Val Pro Ser Glu Asp Glu Trp Tyr Cys
                 350                 355                 360

 Pro Glu Cys Arg Asn Asp Ala Ser Glu Val Val Leu Ala Gly Glu
                 365                 370                 375

 Arg Leu Arg Glu Ser Lys Lys Lys Ala Lys Met Ala Ser Ala Thr
                 380                 385                 390

 Ser Ser Ser Gln Arg Asp Trp Gly Lys Gly Met Ala Cys Val Gly
                 395                 400                 405

 Arg Thr Lys Glu Cys Thr Ile Val Pro Ser Asn His Tyr Gly Pro
                 410                 415                 420

 Ile Pro Gly Ile Pro Val Gly Thr Met Trp Arg Phe Arg Val Gln
                 425                 430                 435

 Val Ser Glu Ser Gly Val His Arg Pro His Val Ala Gly Ile His
                 440                 445                 450

 Gly Arg Ser Asn Asp Gly Ala Tyr Ser Leu Val Leu Ala Gly Gly
                 455                 460                 465

 Tyr Glu Asp Asp Val Asp His Gly Asn Phe Phe Thr Tyr Thr Gly
                 470                 475                 480

 Ser Gly Gly Arg Asp Leu Ser Gly Asn Lys Arg Thr Ala Glu Gln
                 485                 490                 495

 Ser Cys Asp Gln Lys Leu Thr Asn Thr Asn Arg Ala Leu Ala Leu
                 500                 505                 510

 Asn Cys Phe Ala Pro Ile Asn Asp Gln Glu Gly Ala Glu Ala Lys
                 515                 520                 525

 Asp Trp Arg Ser Gly Lys Pro Val Arg Val Val Arg Asn Val Lys
                 530                 535                 540

 Gly Gly Lys Asn Ser Lys Tyr Ala Pro Ala Glu Gly Asn Arg Tyr
                 545                 550                 555

 Asp Gly Ile Tyr Lys Val Val Lys Tyr Trp Pro Glu Lys Gly Lys
                 560                 565                 570

 Ser Gly Phe Leu Val Trp Arg Tyr Leu Leu Arg Arg Asp Asp Asp
                 575                 580                 585

 Glu Pro Gly Pro Trp Thr Lys Glu Gly Lys Asp Arg Ile Lys Lys
                 590                 595                 600

 Leu Gly Leu Thr Met Gln Tyr Pro Glu Gly Tyr Leu Glu Ala Leu
                 605                 610                 615

 Ala Asn Arg Glu Arg Glu Lys Glu Asn Ser Lys Arg Glu Glu Glu
                 620                 625                 630

 Glu Gln Gln Glu Gly Gly Phe Ala Ser Pro Arg Thr Gly Lys Gly
                 635                 640                 645

 Lys Trp Lys Arg Lys Ser Ala Gly Gly Gly Pro Ser Arg Ala Gly
                 650                 655                 660

 Ser Pro Arg Arg Thr Ser Lys Lys Thr Lys Val Glu Pro Tyr Ser
                 665                 670                 675

 Leu Thr Ala Gln Gln Ser Ser Leu Ile Arg Glu Asp Lys Ser Asn
                 680                 685                 690

 Ala Lys Leu Trp Asn Glu Val Leu Ala Ser Leu Lys Asp Arg Pro
                 695                 700                 705

 Ala Ser Gly Ser Pro Phe Gln Leu Phe Leu Ser Lys Val Glu Glu
                 710                 715                 720

 Thr Phe Gln Cys Ile Cys Cys Gln Glu Leu Val Phe Arg Pro Ile
                 725                 730                 735

 Thr Thr Val Cys Gln His Asn Val Cys Lys Asp Cys Leu Asp Arg
                 740                 745                 750

 Ser Phe Arg Ala Gln Val Phe Ser Cys Pro Ala Cys Arg Tyr Asp
                 755                 760                 765

 Leu Gly Arg Ser Tyr Ala Met Gln Val Asn Gln Pro Leu Gln Thr
                 770                 775                 780

 Val Leu Asn Gln Leu Phe Pro Gly Tyr Gly Asn Gly Arg
                 785                 790

<210> 4229
<211> 860
<212> DNA
<213> Homo sapien

<400> 4229
 ggcacgagga gaagatggtg ctgcggcggc tgctggccgc cctgctgcac 50

 agcccgcagc tggtggaacg tctgtcagag tcgcggccta tccgacgtgc 100

 ggcgcagctc acggccttcg cactgctgca ggcccagctg cggggccagg 150

 acgcggcccg ccgcctgcag gacctcgcgg ctgggcccgt gggctccctg 200

 tgccgccgcg ctgagcgatt tagagacgcc ttcacccagg agctacgccg 250

 cggcctccga ggccgctcgg ggccaccacc aggtagccag aggggccctg 300

 gcgcaaacat ttaatcctgg gctgtgcggg gccgaggctg cttgcttttc 350

 cttccgggct ctacagtggc atcaatgtgg aggggtcatt ccgggcactg 400

 cgcgcggctt cgaatcccga ctgggattgt tggcctgcag acatcccacg 450

 cataagagcc taggccagac cgcccgctcc gttgaagtct tgtgattgga 500

 caagacacag tgtggagaaa gacccctaag cctaacagag atgaaggtag 550

 gctgggtcca gacacggcac ctacggagag ccacggaccg aagccagaga 600

 gcctttcctc tgcaagtggg actgaaactc ttgacagatg ctgctcaatc 650

 tgactggtat agcaggacag ttaattccag ggacgatatg gatgaaaaga 700

 caaccctaca gctgccaaat tcctttgatt aaatgtgtga gctggttgat 750

 aggcatgagt gtgatacttc tcaggcaaga tgtgttaaga ataccgggga 800

 ctgtaggcct atggtaataa taaacacgta ttttatgaaa tgaaaaaaaa 850

 aaaaaaaaaa 860

<210> 4230
<211> 99
<212> PRT
<213> Homo sapien

<400> 4230
 Met Val Leu Arg Arg Leu Leu Ala Ala Leu Leu His Ser Pro Gln
   1               5                  10                  15

 Leu Val Glu Arg Leu Ser Glu Ser Arg Pro Ile Arg Arg Ala Ala
                  20                  25                  30

 Gln Leu Thr Ala Phe Ala Leu Leu Gln Ala Gln Leu Arg Gly Gln
                  35                  40                  45

 Asp Ala Ala Arg Arg Leu Gln Asp Leu Ala Ala Gly Pro Val Gly
                  50                  55                  60

 Ser Leu Cys Arg Arg Ala Glu Arg Phe Arg Asp Ala Phe Thr Gln
                  65                  70                  75

 Glu Leu Arg Arg Gly Leu Arg Gly Arg Ser Gly Pro Pro Pro Gly
                  80                  85                  90

 Ser Gln Arg Gly Pro Gly Ala Asn Ile
                  95

<210> 4231
<211> 7195
<212> DNA
<213> Homo sapien

<400> 4231
 cttcctcatt ggcgccgtgc agagaggcgg aatgttcaac tcctaactgc 50

 ggcggaaacg tgggagccgc gcgggccgct gtcgtcccaa cccccgccgc 100

 cctcgtcgcg cgcggggcct ccgcgccccc ggctgctgct cacgccccgc 150

 ccgggagcca gattttgtgg aagtataata ctttgtcatt atgagatgtc 200

 gtctctcggt gcctcctttg tgcaaattaa atttgatgac ttgcagtttt 250

 ttgaaaactg cggtggagga agttttggga gtgtttatcg agccaaatgg 300

 atatcacagg acaaggaggt ggctgtaaag aagctcctca aaatagagaa 350

 agaggcagaa atactcagtg tcctcagtca cagaaacatc atccagtttt 400

 atggagtaat tcttgaacct cccaactatg gcattgtcac agaatatgct 450

 tctctgggat cactctatga ttacattaac agtaacagaa gtgaggagat 500

 ggatatggat cacattatga cctgggccac tgatgtagcc aaaggaatgc 550

 attatttaca tatggaggct cctgtcaagg tgattcacag agacctcaag 600

 tcaagaaacg ttgttatagc tgctgatgga gtattgaaga tctgtgactt 650

 tggtgcctct cggttccata accatacaac acacatgtcc ttggttggaa 700

 ctttcccatg gatggctcca gaagttatcc agagtctccc tgtgtcagaa 750

 acttgtgaca catattccta tggtgtggtt ctctgggaga tgctaacaag 800

 ggaggtcccc tttaaaggtt tggaaggatt acaagtagct tggcttgtag 850

 tggaaaaaaa cgagagatta accattccaa gcagttgccc cagaagtttt 900

 gctgaactgt tacatcagtg ttgggaagct gatgccaaga aacggccatc 950

 attcaagcaa atcatttcaa tcctggagtc catgtcaaat gacacgagcc 1000

 ttcctgacaa gtgtaactca ttcctacaca acaaggcgga gtggaggtgc 1050

 gaaattgagg caactcttga gaggctaaag aaactagagc gtgatctcag 1100

 ctttaaggag caggagctta aagaacgaga aagacgttta aagatgtggg 1150

 agcaaaagct gacagagcag tccaacaccc cgcttctctt gcctcttgct 1200

 gcaagaatgt ctgaggagtc ttactttgaa tctaaaacag aggagtcaaa 1250

 cagtgcagag atgtcatgtc agatcacagc aacaagtaac ggggagggcc 1300

 atggcatgaa cccaagtctg caggccatga tgctgatggg ctttggggat 1350

 atcttctcaa tgaacaaagc aggagctgtg atgcattctg ggatgcagat 1400

 aaacatgcaa gccaagcaga attcttccaa aaccacatct aagagaaggg 1450

 ggaagaaagt caacatggct ctggggttca gtgattttga cttgtcagaa 1500

 ggtgacgatg atgatgatga tgacggtgag gaggaggata atgacatgga 1550

 taatagtgaa tgaaagcaga aagcaaagta ataaaatcac aaatgtttgg 1600

 aaaacacaaa agtaacttgt ttatctcagt ctgtacaaaa acagtaagga 1650

 ggcagaaagc caagcactgc atttttaggc caatcacatt tacatgaccg 1700

 taatttctta tcaattctac ttttattttt gcttacagaa aaacgggggg 1750

 agaattaagc caaagaagta tatttatgaa tcagcaaatg tggtgcctga 1800

 ttatagaaat ttgtgatccc tatatacaat ataggatttt taaagttgag 1850

 acattctggc tttttctttt aatgaatact ttttagtttg tattggactt 1900

 tatttccttt attcaaatca tttttaaaaa ctaacatttt gaacaaacat 1950

 tcttaactcc taattgttct tagacacgta gtaattctgt gacatacttt 2000

 ttttttctta tagcaataca ctgtaatatc agaaatggtt ggcctgagca 2050

 acctagtaag acttcgtctc tactaataat taaaaaacta gctggcatgg 2100

 tagcacacac ctgtagtccc agatacttgg gaggccaagg caggaggatt 2150

 gcttgagacc tagcaatcag tcagggctgc agtgagccat gaggcaccac 2200

 tgcactctag cctgggcaag agaacaagat cctgtctcaa aaaacaaaaa 2250

 aaagaaagaa ttgatagtac aaaatccaac aacaatactg agatgatcta 2300

 agaaggttat aacaaaatgc tcttcagaaa tacctaagtg ctgagaattt 2350

 ttagtactaa agagcacagc tgctcaaagt aaagcctgag cagtgttctc 2400

 agtaatgtat ttgaaggaaa aataccctga tttgaaacca acagcagatg 2450

 ttgcaaactt tcataccact gctggccatg gaagcctctt aacaacacac 2500

 tgtcatttaa ggctgtgctt gtgctttata caaagagaaa gaggtggtct 2550

 taaggggatg cttccagggg ggtgagttca tgcctctcct gtattttcca 2600

 gcaagtgggg tatgtgtggt ggtttgtttt ttagaggggc ataataatcc 2650

 aggattctaa gcatatgctc agctatttta aagaggaaat taaatattat 2700

 aaaagaaata gtaaagataa gttatcctca cttaggcaaa agcacaggtc 2750

 ctttccatat caagtttagc ctaccagggt tgttttttgt tttaaccctg 2800

 cttaataatg ttggtgtttt agaagtagat acaggcactg ctctgaaaac 2850

 ctggctagcc aaggatattc tcagaatgtt atcacctgtt tgtcaaagct 2900

 tgtttaaatt ataaaacact tttaattata tatatgaggc aaaagaacta 2950

 agactttttt caaactaaat tagaaaggag tgtcattatt tgactgttaa 3000

 accaaaatat ttttggtggg tctttttatg gaagtttaaa gaaaggacat 3050

 catcatagat atgatctaac agtatttcta actatatttg atcattaaaa 3100

 gcctcttgga atttgaagcg tgacgtgttt ctaatgcccc ttgagaggtg 3150

 aaaaatacca cataatgatc agtatgctgt gccagcttca tttggggaga 3200

 aataactagt agaaagttct gggtgtgagg tgtacagcag tctaggtggc 3250

 atagtgatga agaaagggat cagagtctga ctgtcactca gaatcctggg 3300

 ctcagttgct tgacaacctt gggaaaattg ttttatcttt gtgcgtctgt 3350

 ttgctgatct tcagcgtggg aataataaca gtacctactt gaaaggatca 3400

 ttgtgcggat taaaagaaat aatatatgta aagcacttta acacagcacc 3450

 aggcccacgg aaagtggcta atgttagcta ctatgaatgg tgccagtgaa 3500

 gacactgaaa aataagtgat ttcagtaacc ttctggaaag ctatcagttt 3550

 caaataatat tttctctgta gtatgagatg aaattaaaag tggatagctt 3600

 tcaggaaaga taaagagaac atgcttagaa tgtaagctaa acagattttt 3650

 tctgttgctc tttgaaaact atgagccctg gccagcttaa cctggtctga 3700

 ggtgagacta aacacaaaaa cagtagataa atctctccct aaaagatgga 3750

 ttcccccaca tacccatgct actagtttct ctgtctattc acacatatgt 3800

 acaaatacat gaacacagcc tgtctgtgct cagacataga gaagtactac 3850

 ctgacttgag tcaatgcacc caagaagaaa agcttggagt agagcagaag 3900

 ggagggcttg ggactcctgt ctttccagca tgccctgggg tgcagtggtc 3950

 agccacctga agagagagcc aatagcatgg ggtttacaag gcaaagatag 4000

 tcattcattc aacacatatt catagagctc cttctctgtg ccagacactg 4050

 ttctggaaga tagctagatg aaaatctttg cactcacaga gcttacatgc 4100

 cagtgagtga agatcgatga taaataaagc aaatgcatca tatgttcaca 4150

 tttgataagt atatgccaaa aaatgaagcc gggaaggagg acaaggccca 4200

 tgggtgggtg ttgaggtttt taaagtgtgg tcaggaaagg ccccactgat 4250

 aaggtaacat ttgagcaagt ctgaaaaagg caaggggatc tttggggcta 4300

 acttcgggat ccctgcactt tatgtaagaa tgtaaacctg gagtctcatt 4350

 taagaatgat cagcaatacg tttagaacat atgaactgaa tgaaatggac 4400

 attttttctt aatttatgta taaatccata tgattataca taaagttctg 4450

 atgcattaat aaaagcagcc aaatagggcc aaagagaaaa ataacaggac 4500

 tctgtactgg acctaacttt atcattaatt aggtaatatt ttcctcattt 4550

 ctttactgct gccattttcc tcaccagtat tccagagatg gtcatagctc 4600

 attactctac caccaagaac ctaaaaggaa ttagaataca gcagaattgg 4650

 cctcagtgaa gagcttaaaa ttgttctcct cgtagaactg gactattgat 4700

 cattaccacg tgacgttggc tctattactt tctgttccca atgtccttct 4750

 agtggtttga aaatgttaaa acatccctaa aatctaaatc atataatcag 4800

 aattctatag tgtcccactc tatctgtaaa gatcatttgg aagactttag 4850

 actctattaa ttttaaaagg aatatttatt agccatatgc agaatttcta 4900

 atgatgatat tgtacagctt ctaattcact tttcagatca gtgtttgaaa 4950

 tggcaattat cagtgttgga tttagttcca actacttgat ttacaaaaat 5000

 gtacatttag aggttaaaag aaacagtgag aaatgtaaac attcaaaatg 5050

 ataattgaat ctctcagttg tgggaataat tatcagagac atgcaactga 5100

 aaatgtctca cctttcatct ttttttctta attcataaag ttatcttgta 5150

 gaatttgatg agaccctccc tagtcattct caactggggc ggtgctgtca 5200

 ccgaatggtg tttgagagtg ttggggctag ggcacatttt tggttgtcac 5250

 agcaactggg gtggcatttg ctgcccagtg ccaggaatag taacattatg 5300

 aatgccaggg acagtgtgct cagtaaagtc ttccatccaa aaggggcagg 5350

 gcacggtggc tcacgcctgt aatcccagca ctttgggagg ccaaggtggg 5400

 cggatcacct gatgtcaggg gttcgagacc agcctggcca acatggtgaa 5450

 accctgttgc tactaaaaat acaaaaattg gctgggtgtg gtgtcacatg 5500

 ccagtaaccc cagctactag ggaggctgag gcaggagaat cacttgaacc 5550

 cgggaggcag aggttgcagt gagctgagat tgcaccacta cactccagcc 5600

 tggatgacag agtgagactt catctcaaaa aaaaaaaaaa acaaaaaaaa 5650

 acaacccggt agcattgtcc cttccccact gacaaactta tcaaatccag 5700

 aagctttaga gtttcgtctc taattatttt tctcctgaac aaaattaccc 5750

 aagtcaaaac aaaatgtatt tttagaatta cggcagcata cgacctgaat 5800

 tttgtgagtt tcgtggcttt atcttaaatc accatttccc taaaaatggt 5850

 ttctttctcc ttagaaatgc tggtggcaac ttgatgaaac agccaaatgc 5900

 accagggcag gtcactttcc cattacactg attccacaat taaaaaaaaa 5950

 aaagaaaaaa aactcattga gatagctaca gttctatagg ttaatttaaa 6000

 gcctcctttt tctactcatt tttgaaagca aaattacatt ttactatttt 6050

 acataaccag tgaaaagacg ttgaaagcct acagctcact gtttttggtg 6100

 ctctggaaat gttgagggtg ggtttttaac cagtgatttt taacgtgcag 6150

 tgaatttgtt agacttttaa acaccagcta aggtagtcaa acttgatccc 6200

 cattaaaaat caaggaatta ggggtcgggg gagggtttag gagtgatcca 6250

 gaatgacctc ccagaattac tgtgcgtaca actttatttt tcagagtttt 6300

 cattggaatg gtaagagttt tatgaaagac agttttaaaa cttattctga 6350

 gttaaatatt aatactttaa aaaattattg tactagactt attgcagcct 6400

 tttgaaagta gcagagtttc atcataccac atatataaca gagcataaat 6450

 tttctataat caggcacctt ttgctgcttt tgagtaagac tgttttcctg 6500

 tttaagtgtt aagcatcgcc agacataaaa atctattctc tcctctcgat 6550

 tgtagcatag cctgacagct ctagatacag catttctatg atgaaaaatg 6600

 agtatccatc aggaaatcta gaagactagc cgtgttttct cagactccac 6650

 ctttgtttgc actctgttgc ctgtgaggag ctttctggca tgtgattatt 6700

 tacttcaaaa ctagagttcc aagcacctac attaattatt ttatattgtg 6750

 tgcagaatag tatatctttt aatgtcagat atgatacact gcacatattg 6800

 cttttgcact cttaaaattt ttgtactaaa taatagaaaa tatttatatt 6850

 ctttgagtgt gagctttgaa tagatggcat tatcacttta ttgttttttt 6900

 aacaaaaact ttttctcaat tattctattg caatgttatt ctgagcaagt 6950

 cctatgccaa atatcttgta taatgtttgt atggaagatt aaattttact 7000

 cttgtgtggt aagactattt cagttactga ttttatagtt ggaatttgat 7050

 attccagcac aaagtccaca gtgtattcag aaatccaagt tggtgtcata 7100

 catttcattt tgatgtgaac ttttctttgc tttcctttgt tctaagactc 7150

 cattttgcaa taaacgtttt gacagtaaaa aaaaaaaaaa aaaaa 7195

<210> 4232
<211> 455
<212> PRT
<213> Homo sapien

<400> 4232
 Met Ser Ser Leu Gly Ala Ser Phe Val Gln Ile Lys Phe Asp Asp
   1               5                  10                  15

 Leu Gln Phe Phe Glu Asn Cys Gly Gly Gly Ser Phe Gly Ser Val
                  20                  25                  30

 Tyr Arg Ala Lys Trp Ile Ser Gln Asp Lys Glu Val Ala Val Lys
                  35                  40                  45

 Lys Leu Leu Lys Ile Glu Lys Glu Ala Glu Ile Leu Ser Val Leu
                  50                  55                  60

 Ser His Arg Asn Ile Ile Gln Phe Tyr Gly Val Ile Leu Glu Pro
                  65                  70                  75

 Pro Asn Tyr Gly Ile Val Thr Glu Tyr Ala Ser Leu Gly Ser Leu
                  80                  85                  90

 Tyr Asp Tyr Ile Asn Ser Asn Arg Ser Glu Glu Met Asp Met Asp
                  95                 100                 105

 His Ile Met Thr Trp Ala Thr Asp Val Ala Lys Gly Met His Tyr
                 110                 115                 120

 Leu His Met Glu Ala Pro Val Lys Val Ile His Arg Asp Leu Lys
                 125                 130                 135

 Ser Arg Asn Val Val Ile Ala Ala Asp Gly Val Leu Lys Ile Cys
                 140                 145                 150

 Asp Phe Gly Ala Ser Arg Phe His Asn His Thr Thr His Met Ser
                 155                 160                 165

 Leu Val Gly Thr Phe Pro Trp Met Ala Pro Glu Val Ile Gln Ser
                 170                 175                 180

 Leu Pro Val Ser Glu Thr Cys Asp Thr Tyr Ser Tyr Gly Val Val
                 185                 190                 195

 Leu Trp Glu Met Leu Thr Arg Glu Val Pro Phe Lys Gly Leu Glu
                 200                 205                 210

 Gly Leu Gln Val Ala Trp Leu Val Val Glu Lys Asn Glu Arg Leu
                 215                 220                 225

 Thr Ile Pro Ser Ser Cys Pro Arg Ser Phe Ala Glu Leu Leu His
                 230                 235                 240

 Gln Cys Trp Glu Ala Asp Ala Lys Lys Arg Pro Ser Phe Lys Gln
                 245                 250                 255

 Ile Ile Ser Ile Leu Glu Ser Met Ser Asn Asp Thr Ser Leu Pro
                 260                 265                 270

 Asp Lys Cys Asn Ser Phe Leu His Asn Lys Ala Glu Trp Arg Cys
                 275                 280                 285

 Glu Ile Glu Ala Thr Leu Glu Arg Leu Lys Lys Leu Glu Arg Asp
                 290                 295                 300

 Leu Ser Phe Lys Glu Gln Glu Leu Lys Glu Arg Glu Arg Arg Leu
                 305                 310                 315

 Lys Met Trp Glu Gln Lys Leu Thr Glu Gln Ser Asn Thr Pro Leu
                 320                 325                 330

 Leu Leu Pro Leu Ala Ala Arg Met Ser Glu Glu Ser Tyr Phe Glu
                 335                 340                 345

 Ser Lys Thr Glu Glu Ser Asn Ser Ala Glu Met Ser Cys Gln Ile
                 350                 355                 360

 Thr Ala Thr Ser Asn Gly Glu Gly His Gly Met Asn Pro Ser Leu
                 365                 370                 375

 Gln Ala Met Met Leu Met Gly Phe Gly Asp Ile Phe Ser Met Asn
                 380                 385                 390

 Lys Ala Gly Ala Val Met His Ser Gly Met Gln Ile Asn Met Gln
                 395                 400                 405

 Ala Lys Gln Asn Ser Ser Lys Thr Thr Ser Lys Arg Arg Gly Lys
                 410                 415                 420

 Lys Val Asn Met Ala Leu Gly Phe Ser Asp Phe Asp Leu Ser Glu
                 425                 430                 435

 Gly Asp Asp Asp Asp Asp Asp Asp Gly Glu Glu Glu Asp Asn Asp
                 440                 445                 450

 Met Asp Asn Ser Glu
                 455

<210> 4233
<211> 7195
<212> DNA
<213> Homo sapien

<400> 4233
 cttcctcatt ggcgccgtgc agagaggcgg aatgttcaac tcctaactgc 50

 ggcggaaacg tgggagccgc gcgggccgct gtcgtcccaa cccccgccgc 100

 cctcgtcgcg cgcggggcct ccgcgccccc ggctgctgct cacgccccgc 150

 ccgggagcca gattttgtgg aagtataata ctttgtcatt atgagatgtc 200

 gtctctcggt gcctcctttg tgcaaattaa atttgatgac ttgcagtttt 250

 ttgaaaactg cggtggagga agttttggga gtgtttatcg agccaaatgg 300

 atatcacagg acaaggaggt ggctgtaaag aagctcctca aaatagagaa 350

 agaggcagaa atactcagtg tcctcagtca cagaaacatc atccagtttt 400

 atggagtaat tcttgaacct cccaactatg gcattgtcac agaatatgct 450

 tctctgggat cactctatga ttacattaac agtaacagaa gtgaggagat 500

 ggatatggat cacattatga cctgggccac tgatgtagcc aaaggaatgc 550

 attatttaca tatggaggct cctgtcaagg tgattcacag agacctcaag 600

 tcaagaaacg ttgttatagc tgctgatgga gtattgaaga tctgtgactt 650

 tggtgcctct cggttccata accatacaac acacatgtcc ttggttggaa 700

 ctttcccatg gatggctcca gaagttatcc agagtctccc tgtgtcagaa 750

 acttgtgaca catattccta tggtgtggtt ctctgggaga tgctaacaag 800

 ggaggtcccc tttaaaggtt tggaaggatt acaagtagct tggcttgtag 850

 tggaaaaaaa cgagagatta accattccaa gcagttgccc cagaagtttt 900

 gctgaactgt tacatcagtg ttgggaagct gatgccaaga aacggccatc 950

 attcaagcaa atcatttcaa tcctggagtc catgtcaaat gacacgagcc 1000

 ttcctgacaa gtgtaactca ttcctacaca acaaggcgga gtggaggtgc 1050

 gaaattgagg caactcttga gaggctaaag aaactagagc gtgatctcag 1100

 ctttaaggag caggagctta aagaacgaga aagacgttta aagatgtggg 1150

 agcaaaagct gacagagcag tccaacaccc cgcttctctt gcctcttgct 1200

 gcaagaatgt ctgaggagtc ttactttgaa tctaaaacag aggagtcaaa 1250

 cagtgcagag atgtcatgtc agatcacagc aacaagtaac ggggagggcc 1300

 atggcatgaa cccaagtctg caggccatga tgctgatggg ctttggggat 1350

 atcttctcaa tgaacaaagc aggagctgtg atgcattctg ggatgcagat 1400

 aaacatgcaa gccaagcaga attcttccaa aaccacatct aagagaaggg 1450

 ggaagaaagt caacatggct ctggggttca gtgattttga cttgtcagaa 1500

 ggtgacgatg atgatgatga tgacggtgag gaggaggata atgacatgga 1550

 taatagtgaa tgaaagcaga aagcaaagta ataaaatcac aaatgtttgg 1600

 aaaacacaaa agtaacttgt ttatctcagt ctgtacaaaa acagtaagga 1650

 ggcagaaagc caagcactgc atttttaggc caatcacatt tacatgaccg 1700

 taatttctta tcaattctac ttttattttt gcttacagaa aaacgggggg 1750

 agaattaagc caaagaagta tatttatgaa tcagcaaatg tggtgcctga 1800

 ttatagaaat ttgtgatccc tatatacaat ataggatttt taaagttgag 1850

 acattctggc tttttctttt aatgaatact ttttagtttg tattggactt 1900

 tatttccttt attcaaatca tttttaaaaa ctaacatttt gaacaaacat 1950

 tcttaactcc taattgttct tagacacgta gtaattctgt gacatacttt 2000

 ttttttctta tagcaataca ctgtaatatc agaaatggtt ggcctgagca 2050

 acctagtaag acttcgtctc tactaataat taaaaaacta gctggcatgg 2100

 tagcacacac ctgtagtccc agatacttgg gaggccaagg caggaggatt 2150

 gcttgagacc tagcaatcag tcagggctgc agtgagccat gaggcaccac 2200

 tgcactctag cctgggcaag agaacaagat cctgtctcaa aaaacaaaaa 2250

 aaagaaagaa ttgatagtac aaaatccaac aacaatactg agatgatcta 2300

 agaaggttat aacaaaatgc tcttcagaaa tacctaagtg ctgagaattt 2350

 ttagtactaa agagcacagc tgctcaaagt aaagcctgag cagtgttctc 2400

 agtaatgtat ttgaaggaaa aataccctga tttgaaacca acagcagatg 2450

 ttgcaaactt tcataccact gctggccatg gaagcctctt aacaacacac 2500

 tgtcatttaa ggctgtgctt gtgctttata caaagagaaa gaggtggtct 2550

 taaggggatg cttccagggg ggtgagttca tgcctctcct gtattttcca 2600

 gcaagtgggg tatgtgtggt ggtttgtttt ttagaggggc ataataatcc 2650

 aggattctaa gcatatgctc agctatttta aagaggaaat taaatattat 2700

 aaaagaaata gtaaagataa gttatcctca cttaggcaaa agcacaggtc 2750

 ctttccatat caagtttagc ctaccagggt tgttttttgt tttaaccctg 2800

 cttaataatg ttggtgtttt agaagtagat acaggcactg ctctgaaaac 2850

 ctggctagcc aaggatattc tcagaatgtt atcacctgtt tgtcaaagct 2900

 tgtttaaatt ataaaacact tttaattata tatatgaggc aaaagaacta 2950

 agactttttt caaactaaat tagaaaggag tgtcattatt tgactgttaa 3000

 accaaaatat ttttggtggg tctttttatg gaagtttaaa gaaaggacat 3050

 catcatagat atgatctaac agtatttcta actatatttg atcattaaaa 3100

 gcctcttgga atttgaagcg tgacgtgttt ctaatgcccc ttgagaggtg 3150

 aaaaatacca cataatgatc agtatgctgt gccagcttca tttggggaga 3200

 aataactagt agaaagttct gggtgtgagg tgtacagcag tctaggtggc 3250

 atagtgatga agaaagggat cagagtctga ctgtcactca gaatcctggg 3300

 ctcagttgct tgacaacctt gggaaaattg ttttatcttt gtgcgtctgt 3350

 ttgctgatct tcagcgtggg aataataaca gtacctactt gaaaggatca 3400

 ttgtgcggat taaaagaaat aatatatgta aagcacttta acacagcacc 3450

 aggcccacgg aaagtggcta atgttagcta ctatgaatgg tgccagtgaa 3500

 gacactgaaa aataagtgat ttcagtaacc ttctggaaag ctatcagttt 3550

 caaataatat tttctctgta gtatgagatg aaattaaaag tggatagctt 3600

 tcaggaaaga taaagagaac atgcttagaa tgtaagctaa acagattttt 3650

 tctgttgctc tttgaaaact atgagccctg gccagcttaa cctggtctga 3700

 ggtgagacta aacacaaaaa cagtagataa atctctccct aaaagatgga 3750

 ttcccccaca tacccatgct actagtttct ctgtctattc acacatatgt 3800

 acaaatacat gaacacagcc tgtctgtgct cagacataga gaagtactac 3850

 ctgacttgag tcaatgcacc caagaagaaa agcttggagt agagcagaag 3900

 ggagggcttg ggactcctgt ctttccagca tgccctgggg tgcagtggtc 3950

 agccacctga agagagagcc aatagcatgg ggtttacaag gcaaagatag 4000

 tcattcattc aacacatatt catagagctc cttctctgtg ccagacactg 4050

 ttctggaaga tagctagatg aaaatctttg cactcacaga gcttacatgc 4100

 cagtgagtga agatcgatga taaataaagc aaatgcatca tatgttcaca 4150

 tttgataagt atatgccaaa aaatgaagcc gggaaggagg acaaggccca 4200

 tgggtgggtg ttgaggtttt taaagtgtgg tcaggaaagg ccccactgat 4250

 aaggtaacat ttgagcaagt ctgaaaaagg caaggggatc tttggggcta 4300

 acttcgggat ccctgcactt tatgtaagaa tgtaaacctg gagtctcatt 4350

 taagaatgat cagcaatacg tttagaacat atgaactgaa tgaaatggac 4400

 attttttctt aatttatgta taaatccata tgattataca taaagttctg 4450

 atgcattaat aaaagcagcc aaatagggcc aaagagaaaa ataacaggac 4500

 tctgtactgg acctaacttt atcattaatt aggtaatatt ttcctcattt 4550

 ctttactgct gccattttcc tcaccagtat tccagagatg gtcatagctc 4600

 attactctac caccaagaac ctaaaaggaa ttagaataca gcagaattgg 4650

 cctcagtgaa gagcttaaaa ttgttctcct cgtagaactg gactattgat 4700

 cattaccacg tgacgttggc tctattactt tctgttccca atgtccttct 4750

 agtggtttga aaatgttaaa acatccctaa aatctaaatc atataatcag 4800

 aattctatag tgtcccactc tatctgtaaa gatcatttgg aagactttag 4850

 actctattaa ttttaaaagg aatatttatt agccatatgc agaatttcta 4900

 atgatgatat tgtacagctt ctaattcact tttcagatca gtgtttgaaa 4950

 tggcaattat cagtgttgga tttagttcca actacttgat ttacaaaaat 5000

 gtacatttag aggttaaaag aaacagtgag aaatgtaaac attcaaaatg 5050

 ataattgaat ctctcagttg tgggaataat tatcagagac atgcaactga 5100

 aaatgtctca cctttcatct ttttttctta attcataaag ttatcttgta 5150

 gaatttgatg agaccctccc tagtcattct caactggggc ggtgctgtca 5200

 ccgaatggtg tttgagagtg ttggggctag ggcacatttt tggttgtcac 5250

 agcaactggg gtggcatttg ctgcccagtg ccaggaatag taacattatg 5300

 aatgccaggg acagtgtgct cagtaaagtc ttccatccaa aaggggcagg 5350

 gcacggtggc tcacgcctgt aatcccagca ctttgggagg ccaaggtggg 5400

 cggatcacct gatgtcaggg gttcgagacc agcctggcca acatggtgaa 5450

 accctgttgc tactaaaaat acaaaaattg gctgggtgtg gtgtcacatg 5500

 ccagtaaccc cagctactag ggaggctgag gcaggagaat cacttgaacc 5550

 cgggaggcag aggttgcagt gagctgagat tgcaccacta cactccagcc 5600

 tggatgacag agtgagactt catctcaaaa aaaaaaaaaa acaaaaaaaa 5650

 acaacccggt agcattgtcc cttccccact gacaaactta tcaaatccag 5700

 aagctttaga gtttcgtctc taattatttt tctcctgaac aaaattaccc 5750

 aagtcaaaac aaaatgtatt tttagaatta cggcagcata cgacctgaat 5800

 tttgtgagtt tcgtggcttt atcttaaatc accatttccc taaaaatggt 5850

 ttctttctcc ttagaaatgc tggtggcaac ttgatgaaac agccaaatgc 5900

 accagggcag gtcactttcc cattacactg attccacaat taaaaaaaaa 5950

 aaagaaaaaa aactcattga gatagctaca gttctatagg ttaatttaaa 6000

 gcctcctttt tctactcatt tttgaaagca aaattacatt ttactatttt 6050

 acataaccag tgaaaagacg ttgaaagcct acagctcact gtttttggtg 6100

 ctctggaaat gttgagggtg ggtttttaac cagtgatttt taacgtgcag 6150

 tgaatttgtt agacttttaa acaccagcta aggtagtcaa acttgatccc 6200

 cattaaaaat caaggaatta ggggtcgggg gagggtttag gagtgatcca 6250

 gaatgacctc ccagaattac tgtgcgtaca actttatttt tcagagtttt 6300

 cattggaatg gtaagagttt tatgaaagac agttttaaaa cttattctga 6350

 gttaaatatt aatactttaa aaaattattg tactagactt attgcagcct 6400

 tttgaaagta gcagagtttc atcataccac atatataaca gagcataaat 6450

 tttctataat caggcacctt ttgctgcttt tgagtaagac tgttttcctg 6500

 tttaagtgtt aagcatcgcc agacataaaa atctattctc tcctctcgat 6550

 tgtagcatag cctgacagct ctagatacag catttctatg atgaaaaatg 6600

 agtatccatc aggaaatcta gaagactagc cgtgttttct cagactccac 6650

 ctttgtttgc actctgttgc ctgtgaggag ctttctggca tgtgattatt 6700

 tacttcaaaa ctagagttcc aagcacctac attaattatt ttatattgtg 6750

 tgcagaatag tatatctttt aatgtcagat atgatacact gcacatattg 6800

 cttttgcact cttaaaattt ttgtactaaa taatagaaaa tatttatatt 6850

 ctttgagtgt gagctttgaa tagatggcat tatcacttta ttgttttttt 6900

 aacaaaaact ttttctcaat tattctattg caatgttatt ctgagcaagt 6950

 cctatgccaa atatcttgta taatgtttgt atggaagatt aaattttact 7000

 cttgtgtggt aagactattt cagttactga ttttatagtt ggaatttgat 7050

 attccagcac aaagtccaca gtgtattcag aaatccaagt tggtgtcata 7100

 catttcattt tgatgtgaac ttttctttgc tttcctttgt tctaagactc 7150

 cattttgcaa taaacgtttt gacagtaaaa aaaaaaaaaa aaaaa 7195

<210> 4234
<211> 455
<212> PRT
<213> Homo sapien

<400> 4234
 Met Ser Ser Leu Gly Ala Ser Phe Val Gln Ile Lys Phe Asp Asp
   1               5                  10                  15

 Leu Gln Phe Phe Glu Asn Cys Gly Gly Gly Ser Phe Gly Ser Val
                  20                  25                  30

 Tyr Arg Ala Lys Trp Ile Ser Gln Asp Lys Glu Val Ala Val Lys
                  35                  40                  45

 Lys Leu Leu Lys Ile Glu Lys Glu Ala Glu Ile Leu Ser Val Leu
                  50                  55                  60

 Ser His Arg Asn Ile Ile Gln Phe Tyr Gly Val Ile Leu Glu Pro
                  65                  70                  75

 Pro Asn Tyr Gly Ile Val Thr Glu Tyr Ala Ser Leu Gly Ser Leu
                  80                  85                  90

 Tyr Asp Tyr Ile Asn Ser Asn Arg Ser Glu Glu Met Asp Met Asp
                  95                 100                 105

 His Ile Met Thr Trp Ala Thr Asp Val Ala Lys Gly Met His Tyr
                 110                 115                 120

 Leu His Met Glu Ala Pro Val Lys Val Ile His Arg Asp Leu Lys
                 125                 130                 135

 Ser Arg Asn Val Val Ile Ala Ala Asp Gly Val Leu Lys Ile Cys
                 140                 145                 150

 Asp Phe Gly Ala Ser Arg Phe His Asn His Thr Thr His Met Ser
                 155                 160                 165

 Leu Val Gly Thr Phe Pro Trp Met Ala Pro Glu Val Ile Gln Ser
                 170                 175                 180

 Leu Pro Val Ser Glu Thr Cys Asp Thr Tyr Ser Tyr Gly Val Val
                 185                 190                 195

 Leu Trp Glu Met Leu Thr Arg Glu Val Pro Phe Lys Gly Leu Glu
                 200                 205                 210

 Gly Leu Gln Val Ala Trp Leu Val Val Glu Lys Asn Glu Arg Leu
                 215                 220                 225

 Thr Ile Pro Ser Ser Cys Pro Arg Ser Phe Ala Glu Leu Leu His
                 230                 235                 240

 Gln Cys Trp Glu Ala Asp Ala Lys Lys Arg Pro Ser Phe Lys Gln
                 245                 250                 255

 Ile Ile Ser Ile Leu Glu Ser Met Ser Asn Asp Thr Ser Leu Pro
                 260                 265                 270

 Asp Lys Cys Asn Ser Phe Leu His Asn Lys Ala Glu Trp Arg Cys
                 275                 280                 285

 Glu Ile Glu Ala Thr Leu Glu Arg Leu Lys Lys Leu Glu Arg Asp
                 290                 295                 300

 Leu Ser Phe Lys Glu Gln Glu Leu Lys Glu Arg Glu Arg Arg Leu
                 305                 310                 315

 Lys Met Trp Glu Gln Lys Leu Thr Glu Gln Ser Asn Thr Pro Leu
                 320                 325                 330

 Leu Leu Pro Leu Ala Ala Arg Met Ser Glu Glu Ser Tyr Phe Glu
                 335                 340                 345

 Ser Lys Thr Glu Glu Ser Asn Ser Ala Glu Met Ser Cys Gln Ile
                 350                 355                 360

 Thr Ala Thr Ser Asn Gly Glu Gly His Gly Met Asn Pro Ser Leu
                 365                 370                 375

 Gln Ala Met Met Leu Met Gly Phe Gly Asp Ile Phe Ser Met Asn
                 380                 385                 390

 Lys Ala Gly Ala Val Met His Ser Gly Met Gln Ile Asn Met Gln
                 395                 400                 405

 Ala Lys Gln Asn Ser Ser Lys Thr Thr Ser Lys Arg Arg Gly Lys
                 410                 415                 420

 Lys Val Asn Met Ala Leu Gly Phe Ser Asp Phe Asp Leu Ser Glu
                 425                 430                 435

 Gly Asp Asp Asp Asp Asp Asp Asp Gly Glu Glu Glu Asp Asn Asp
                 440                 445                 450

 Met Asp Asn Ser Glu
                 455

<210> 4235
<211> 2046
<212> DNA
<213> Homo sapien

<400> 4235
 agtttaaaaa tttgtgttgg acttcatgcg ggccacaggt tggacaagct 50

 tgccctaggg cattgtgtgc tttccgtaac ttctcagttg tatttcgtta 100

 tccatgactc tccagtgttt tttctgttgg accacacccg tcacagttca 150

 cagttccaaa gagaaatttc ccagcctatt ctaaatcttg ttaatgacga 200

 agagtccaat gtatctcatt atttgtagcc aattttagac tcttttcaat 250

 acctcccccc cattttaatt agtattgatc atattcagtc tttcatttta 300

 ctcttcatct gtagcgtgac ctcaaggtaa agatgaaact atttcatgaa 350

 aaggggagga gtatggctgt gcattagctc tactccctct ctggtaagta 400

 ctggggagag aacagccctg ccagtactgg gtttgataga ttctaaatat 450

 taatcacaca tcctgcctac agttagccat tttagtttct gggagttctt 500

 tcatgtacat tttcttccat taattgaatt aggtataatt gagatggcaa 550

 taaatatgcc cgtattagaa agaggaaaca aagctacatc cggcttatga 600

 ttttgttgag tcacttctcc cgaggcagcc tttccaatgc ctggtccctt 650

 cccctgagag caggtggact gctggtggtg gctttctttc ctgcagagag 700

 gcactttaga cccatacctg ctgtgagctg aattgatgtt ctcatcctgt 750

 gaaccttctc ccactttaac ctaatttatc tttacttgtt taaagataag 800

 gaaacccaag atgtacttta tttgcaaact caaagcaaat ggcgagccac 850

 ctgtgaccca gtaaccagaa aagaaaccat gccatttgta taagtagaga 900

 cacttcttgt tgaggtaggc aaggctcttg tgagcgattt ttttccccta 950

 gtgagaccta acaaaagaca agctatatca tttctgcctg aaattatctg 1000

 cttgaaaaga tcaaaatatc aggatactta gctcttcaca aatatgaagt 1050

 cattatcaca tttcactgag ccagaaatca ctgttaacag cacacacaaa 1100

 agactacact ggttgaacag caaagagaaa cccgggtctc cagaatcaca 1150

 gtttagtcct tctatattac tgcaagtgac ctgttttttc tgaaggctcc 1200

 ccgcaaatga agtcctggaa tggaaaaaat ccataagtcc ataaattaac 1250

 ttgataaata ttttagaaca gacaaaagaa aatattgagt gatgtagttc 1300

 taatcctcct aatatggaac ctggcaagac tgaatcattt tactgtgaaa 1350

 tatataaaca caatagaatg agccaacatg atggtttctc tccagtaaga 1400

 gtttttcttt tggaaatgag gttaacctag ccccaaatct agcaattctc 1450

 ataaaatccg attttagaat tagcctccca gattaatctg aatgattgac 1500

 ttattttttc ttaggcaagt cagtaagcca cccactagac agccatatcc 1550

 agcaaaataa gagaagtttc cagatgccaa atgataagcc accatcaacc 1600

 cagcggggaa gccttctggt tggtttggct gtatgagatt caggaaggcc 1650

 agaataccca aaattattca cacgacgtta acttattggt actggctaag 1700

 caatacatgt atttcctaaa ggaggagatg gtcttttggt tgatttatgg 1750

 acacacttgt ttcatctgac tgtaaatata ttgcatgctt tattctgatg 1800

 gtgcactatt tcatccagca agcttttcat ctgagaatgt ttaatgttga 1850

 ccttattctt agagcaagta gatctaaata tttttcagct gagttattag 1900

 ggagtcatta ttctgtggta caatgctgca aaaagcatca tgtggaagaa 1950

 tgggaactat gcttacttta tgaagtgatg tataacacaa tgaaatctgt 2000

 tttacaacta ctgtgctgca tttaattatc ttccattttt gctgtt 2046

<210> 4236
<211> 75
<212> PRT
<213> Homo sapien

<400> 4236
 Ser Leu Lys Ile Cys Val Gly Leu His Ala Gly His Arg Leu Asp
   1               5                  10                  15

 Lys Leu Ala Leu Gly His Cys Val Leu Ser Val Thr Ser Gln Leu
                  20                  25                  30

 Tyr Phe Val Ile His Asp Ser Pro Val Phe Phe Leu Leu Asp His
                  35                  40                  45

 Thr Arg His Ser Ser Gln Phe Gln Arg Glu Ile Ser Gln Pro Ile
                  50                  55                  60

 Leu Asn Leu Val Asn Asp Glu Glu Ser Asn Val Ser His Tyr Leu
                  65                  70                  75

<210> 4237
<211> 1113
<212> DNA
<213> Homo sapien

<400> 4237
 agcgccgccg cggtctgcgg aatgtcaact attcaacatg gaggcggagg 50

 tcgataagct ggaactgatg ttccagaaag ctgagtctga tctggattac 100

 attcaataca ggctggaata tgaaatcaag actaatcatc ctgattcagc 150

 aagtgagaaa aatccagtta cactcttaaa ggaattgtca gtgataaagt 200

 ctcgatatca aactttgtat gcccgcttta aaccagttgc tgttgagcag 250

 aaagagagta agagccgcat ttgtgctact gtgaaaaaga ctatgaatat 300

 gatacaaaaa ctacagaagc aaacagacct ggagctgtca ccactgacta 350

 aagaagagaa aactgcggca gagcaattca aatttcacat gccagattta 400

 tgaagaaatg gacttggaaa ggaaattcta acagagaaga gcttaattcc 450

 ggagaaattt aggaagatgt cttgttaacc cttgatgtct agagattggg 500

 ggctggtgaa gggggtttgg cttcaatgac tggataatga tatctttcat 550

 gagagagatt ataagaagaa gggcagataa tatatgaata aagttcagcc 600

 aaaaggatca aatgagaata aaacgattta aatatatgta cacacgcatg 650

 cacacacaca cttagtcttg taatttcagg ccagaaattc tcaacactat 700

 tttgcatctg ttttcttttt ctaagtcatg ataatataga tgttctggtc 750

 tatcataaaa gaatgtttat gtacatttca gtcattcggt atgtggcttt 800

 gtaaattaaa gtataggcaa aacatttgtg ttatacatga tatataattt 850

 cattttgtaa atgttgattg cacatgtggt cacattattg ttgagactgc 900

 ttttatgtga cctgtagtct cccacagaac ctaaagtaat aagctggctt 950

 ttctgtgata gccacgtttg cgtatttctt tccctatttc ccttgcctgc 1000

 taatgttgaa cagcatgaac ttgctttctg atgctgtttt agactgtccc 1050

 tgttgtatct caataatatc tttgttttcc tacaaaaaaa aaaaaaaaaa 1100

 gaaaaaaaaa aaa 1113

<210> 4238
<211> 121
<212> PRT
<213> Homo sapien

<400> 4238
 Met Glu Ala Glu Val Asp Lys Leu Glu Leu Met Phe Gln Lys Ala
   1               5                  10                  15

 Glu Ser Asp Leu Asp Tyr Ile Gln Tyr Arg Leu Glu Tyr Glu Ile
                  20                  25                  30

 Lys Thr Asn His Pro Asp Ser Ala Ser Glu Lys Asn Pro Val Thr
                  35                  40                  45

 Leu Leu Lys Glu Leu Ser Val Ile Lys Ser Arg Tyr Gln Thr Leu
                  50                  55                  60

 Tyr Ala Arg Phe Lys Pro Val Ala Val Glu Gln Lys Glu Ser Lys
                  65                  70                  75

 Ser Arg Ile Cys Ala Thr Val Lys Lys Thr Met Asn Met Ile Gln
                  80                  85                  90

 Lys Leu Gln Lys Gln Thr Asp Leu Glu Leu Ser Pro Leu Thr Lys
                  95                 100                 105

 Glu Glu Lys Thr Ala Ala Glu Gln Phe Lys Phe His Met Pro Asp
                 110                 115                 120

 Leu


<210> 4239
<211> 829
<212> DNA
<213> Homo sapien

<400> 4239
 gcggcgcagc gcgcggcgca gcgcgcggcg tcagtcttgg ctggcagacc 50

 tgtactccgt actccgtact tcgtagtcgc agcggcgcgg tcttcggcag 100

 tctagtcatc caccgccatc ctgggcccca cgtgttgcct gaccattcct 150

 gagcccaggt gggagccgtg gctgaggtga cggtctcaaa gtggaagagc 200

 ttactgtcac agcaactcct ttgcaagatg ccccggccag gaatagttgc 250

 tgaacacccc aggcctgctg aggtccctcc ttgagtctca tgttcaagca 300

 gtctttgtcc atgaaactgg gaggcgaccg tgttagctgc cagttcctga 350

 cagccacctc tcaccagtgg cttcactctg tgtccctgac ccagcacatg 400

 gcacaagagt gcctgccatc cgtcagtgtt tctacagcag caatccctag 450

 atgctggagc tagaggggac ctgacctgag agaagatacc ttcagtggct 500

 gccaggctgt tccttggaac ctgtgcaggg atgaggcctg cctgtgttaa 550

 tacacctagt gaggagtgga gctgaatttg aatgcaagcc ttggcacctt 600

 aattgagcaa gtttgaaacc tcgcttgttg cccttctgga aggagtcagg 650

 aatttccagt tctgggcctg ggctgtgggt ctggcagaca gacctctggc 700

 cctaggtttg ggtgccaggt tctctgcttc cagaatgaga agctttgctg 750

 tgcaccagga cctgggccct tttggtatct cctgaatgac acacaaggga 800

 tatttaataa atatgcattt aaatatgtg 829

<210> 4240
<211> 50
<212> PRT
<213> Homo sapien

<400> 4240
 Met Lys Leu Gly Gly Asp Arg Val Ser Cys Gln Phe Leu Thr Ala
   1               5                  10                  15

 Thr Ser His Gln Trp Leu His Ser Val Ser Leu Thr Gln His Met
                  20                  25                  30

 Ala Gln Glu Cys Leu Pro Ser Val Ser Val Ser Thr Ala Ala Ile
                  35                  40                  45

 Pro Arg Cys Trp Ser
                  50

<210> 4241
<211> 918
<212> DNA
<213> Homo sapien

<400> 4241
 gagtagctca ccgttaccca agtatgcttc atctcccaaa ccaaacaaca 50

 gctacatgtt caaacgggag cccccagagg gatgtgagcg agtgaaggtc 100

 tttgaggaaa tggcgtctcg tcagcctatc tcggcccctc tcttttcatg 150

 tcctgacaaa aacaaggtta atttcatccc aaccggatca gctttctgtc 200

 ctgtaaaact tctaggcccc ctcttacctg cttctgacct tatgctcaag 250

 aactctccta actctggcca gagctcagct ttggcaactc tgaccgttga 300

 gcagctctca tcccgggttt cctttacgtc tctttctgat gacaccagca 350

 cagcgggctc catggaggcc tctgtccagc agccatccca gcagcagcag 400

 ctcctgcagg aactgcaggg tgaggaccac atctctgctc agaactatgt 450

 gatcatctaa aaaaggggga gctggcctcc accctatgtt ccatggattc 500

 ggaacaagat ttcagacatc tgcatgagtg acaaactttc tgaacaccac 550

 caccaccaat aatacttatc agcatcataa agtatctctt aaacactgat 600

 cttggcaggg acggaactcc tattcagcag tttttgtgga aagcagtaat 650

 gcttgcaaaa cgtgtgtgtc attcagcatt ttaagtggag actatgcatt 700

 tcatagtata tttgacagat tagtactgtg tcctgtgttt tgttccagat 750

 tcttcagtat aaataagctc tatatcaaaa agttgcctgt ctaaatagaa 800

 aatgtcttgc tgtgttttgt cctatggaaa atactgtaat tcaggattat 850

 gtttacaatt gatccaggtg tttgtttcta acttctgtaa tacatacaat 900

 gcaaaaaaaa aaaaaaaa 918

<210> 4242
<211> 152
<212> PRT
<213> Homo sapien

<400> 4242
 Ser Ser Ser Pro Leu Pro Lys Tyr Ala Ser Ser Pro Lys Pro Asn
   1               5                  10                  15

 Asn Ser Tyr Met Phe Lys Arg Glu Pro Pro Glu Gly Cys Glu Arg
                  20                  25                  30

 Val Lys Val Phe Glu Glu Met Ala Ser Arg Gln Pro Ile Ser Ala
                  35                  40                  45

 Pro Leu Phe Ser Cys Pro Asp Lys Asn Lys Val Asn Phe Ile Pro
                  50                  55                  60

 Thr Gly Ser Ala Phe Cys Pro Val Lys Leu Leu Gly Pro Leu Leu
                  65                  70                  75

 Pro Ala Ser Asp Leu Met Leu Lys Asn Ser Pro Asn Ser Gly Gln
                  80                  85                  90

 Ser Ser Ala Leu Ala Thr Leu Thr Val Glu Gln Leu Ser Ser Arg
                  95                 100                 105

 Val Ser Phe Thr Ser Leu Ser Asp Asp Thr Ser Thr Ala Gly Ser
                 110                 115                 120

 Met Glu Ala Ser Val Gln Gln Pro Ser Gln Gln Gln Gln Leu Leu
                 125                 130                 135

 Gln Glu Leu Gln Gly Glu Asp His Ile Ser Ala Gln Asn Tyr Val
                 140                 145                 150

 Ile Ile


<210> 4243
<211> 1781
<212> DNA
<213> Homo sapien

<400> 4243
 agcgggtttt tcgcgccatg tcgtttgctg agagcgggtg gcggtcggct 50

 ctgcggcgcc gcggtcccgg caccccgggc cctgtggctc ggccatcgta 100

 ttcctccttt actcaggggg acagctgggg tgaaggcgaa gtcgacgagg 150

 aggagggatg cgaccaagtg gcccgcgacc tgcgggcgga gttctcggct 200

 ggggcgtggt cagagcccag aaagcgctcg gtgctcccgc cggacgggaa 250

 cgggtcgccc gttctgcccg ataagcgcaa tggtatcttt cccgcggccg 300

 cgggcagcag agcccagcct cggcggtggc cggtccaggt cctctctatt 350

 ctctgctcgc tgctcttcgc cattcttctc gccttcctcc tcgccatcgc 400

 ctacttgatc gttaaagagt tgcatgctga gaatttgaaa aatgaagatg 450

 atgtagacac tggactatta ggattctgga ctctacttat aatatcccta 500

 actgctggat tctcctgttg cagcttttct tggacagtga cttactttga 550

 ttcttttgaa ccaggaatgt ttcctcctac tcctctttca cctgccaggt 600

 tcaagaaact gactggacat tctttccaca tgggctatag catggcgatt 650

 ttgaatggca tcgtagctgc tcttactgta gcatggtgcc tcatgtaaac 700

 ccacactgga gcgatattgt tggcaaaact taatcatgat tgttttgtaa 750

 taacaagaag gagcatcact gtctactcag aagactgaga aacctgctgt 800

 tcattatgta gttcagatat ttatcacaat catcctcatt atggaagacc 850

 ttttaaagca ttgttttaga atgtctgagt attaagatac agattaattg 900

 ggaatatctg agtattaagt actttcttca gagtataaga tgtttacctc 950

 atctttttac ttttgtgtgt gtagttcttt caagttgtag gaaacatttt 1000

 aatggaattt aaactcaaac ttgaatacag gacaatgctt gccttttcat 1050

 gtatgtacta cattttttgc taagaaatac tgatatttct gtttagttga 1100

 gctagaaata cttcttattt atacatttag gaaagcaaat aatgcctact 1150

 actccgactt ttatagaagc tacttttaaa tcagaatatt taatttttga 1200

 tattcatata attaatagaa gttgcattta tattttttat ggggcatagt 1250

 tccttatgtg tttttttaat gtattttcat actacatact gaatttgtat 1300

 gtttttaaaa ttgttacatc tagacaactg taaacattat ttttttagct 1350

 agtgcaaacc tagtacctgc catttttact aatttttgtc tttaaaaaaa 1400

 gcaaaaaagc acattgacct aagttgaaaa ttaagtaagt ttatttttaa 1450

 caaaaaatgc ctgaaaaaag ctaaattatt taagtcatta agatattgag 1500

 aaaaaatttg aaatttttac tatttctgtt tccacaattc caaatattta 1550

 tcttggtgta tatattgtta ctttaacaga acttgcatta ttttgttttt 1600

 aataaatata aacatgaaat ttttgtatgt gagaatgatt gaactagttt 1650

 gttcttaatc tcaaaaattt agttaccaaa gtagaaaagg tattttgata 1700

 ctagatatta aaaactacat atagttaata taattttata atttttgtaa 1750

 ttaaatgtgc ttctgcaaaa aaaaaaaaaa a 1781

<210> 4244
<211> 226
<212> PRT
<213> Homo sapien

<400> 4244
 Met Ser Phe Ala Glu Ser Gly Trp Arg Ser Ala Leu Arg Arg Arg
   1               5                  10                  15

 Gly Pro Gly Thr Pro Gly Pro Val Ala Arg Pro Ser Tyr Ser Ser
                  20                  25                  30

 Phe Thr Gln Gly Asp Ser Trp Gly Glu Gly Glu Val Asp Glu Glu
                  35                  40                  45

 Glu Gly Cys Asp Gln Val Ala Arg Asp Leu Arg Ala Glu Phe Ser
                  50                  55                  60

 Ala Gly Ala Trp Ser Glu Pro Arg Lys Arg Ser Val Leu Pro Pro
                  65                  70                  75

 Asp Gly Asn Gly Ser Pro Val Leu Pro Asp Lys Arg Asn Gly Ile
                  80                  85                  90

 Phe Pro Ala Ala Ala Gly Ser Arg Ala Gln Pro Arg Arg Trp Pro
                  95                 100                 105

 Val Gln Val Leu Ser Ile Leu Cys Ser Leu Leu Phe Ala Ile Leu
                 110                 115                 120

 Leu Ala Phe Leu Leu Ala Ile Ala Tyr Leu Ile Val Lys Glu Leu
                 125                 130                 135

 His Ala Glu Asn Leu Lys Asn Glu Asp Asp Val Asp Thr Gly Leu
                 140                 145                 150

 Leu Gly Phe Trp Thr Leu Leu Ile Ile Ser Leu Thr Ala Gly Phe
                 155                 160                 165

 Ser Cys Cys Ser Phe Ser Trp Thr Val Thr Tyr Phe Asp Ser Phe
                 170                 175                 180

 Glu Pro Gly Met Phe Pro Pro Thr Pro Leu Ser Pro Ala Arg Phe
                 185                 190                 195

 Lys Lys Leu Thr Gly His Ser Phe His Met Gly Tyr Ser Met Ala
                 200                 205                 210

 Ile Leu Asn Gly Ile Val Ala Ala Leu Thr Val Ala Trp Cys Leu
                 215                 220                 225

 Met


<210> 4245
<211> 2364
<212> DNA
<213> Homo sapien

<400> 4245
 ttatatgaac ttttgctatt gaatgtttat ttgtaggcta tttatatcac 50

 ttcataaaga acagttcttt gagaaaagaa taaaggaatg tattcatttc 100

 cagaaaaaga gggttgggga aagtttgcca tgtaggttag tcagaagaaa 150

 gcaattctat tatgcataaa aataacctta aatatgtaag agagtatctc 200

 ctctacttaa aagttattat agtagtcaca ggcatacaga ccacaggaat 250

 tctatggtct taacatattt taaaattaca tttattttaa tgttcttaaa 300

 gtttatgaag aggagtttaa agcaattccc ataattaaat atttactcgg 350

 caactaaaaa ctatttaaca cttgtggtta attatacaca taaacaaatg 400

 gcgacagagt agcctcacta ccacaattac ttcatggtta cacctttgct 450

 ttctaataat aggggctcca gttgctaaat atatttgttt acttacagtt 500

 taagttgagc tgattgttga attctgttat tgttcctgaa ttcaatgagt 550

 atataatttg tagagatgtt gaatagtttg gatcttagtt tttaaggctg 600

 aaaaatctgg ctggatttag tttttaaaaa tttgcatcat caagattccg 650

 tcccaaaaag aaaaagcagt ttttgccatc agcaaggata tctccaccac 700

 tttaatggac aggcctcatt tttggcagct atgctgtttg agatgtagac 750

 tgaatatcca aggttcctcc ctagctcaag tttttacttg tgattacaca 800

 caccacattg aattccgtct tcagaggcaa agatttgggc ttcatatctc 850

 aacagcaaaa gggcctgttc agcaattccc ttcattttag actcatatga 900

 cctcagcgat tgcatgatag tagtaaacta gtctcctgga aataatggat 950

 gtaggtgctt ctagaatatg ttacagaatt tcagacttaa cctattaata 1000

 gataaatgga tcttgactta aggtgacaaa atgaaacttt tattattgct 1050

 taaaaatgct gtgccaatat tgtataacta gctcctctaa tacttttggt 1100

 attttggatt taataataag accttaagca ttttaaatgt gaacatgttc 1150

 agggaagtat gctttgatgt aaatgtctca gatctaagtt gtaacacaat 1200

 tgaatacttg tggcttattc ttggtttaac ttaggaaaac tggttaaaca 1250

 atcccccatt tgggcctgtc atcattttaa tagtgacgat gttctttctg 1300

 aaatcttcag ggtcggagtc aggctgaatt tttttaaaaa ttaaatatta 1350

 tgttcaaatt ctttcctttt tgccattgtg aaaaagcaaa attttaaatg 1400

 atttctcctg ttagaatttt taaaaatacc cacaggttgg accatctttc 1450

 ttatgggttg cacaatgaat ttatatttta aattagatta agtagaatgt 1500

 gaagtacatt tcagatttac tagttttctt tccattgttc attttgggtt 1550

 gcctcagatt cagtgtatat tttaaaatat tggttacata ataggtactc 1600

 aatgaaatgg tttatagtag aatatctaag ctagcacttt attttaaaaa 1650

 gtaacttatt aattaatcac acattgatgg tacaccttgt atttagcaaa 1700

 tgtttgcatg ttgataaaat ctcctatgtc ttctttctta aatccagttg 1750

 ctgattttgt aaaatacagt tgtgataaag cagcattacg ggggggaaaa 1800

 agctatattc caactggtgt taaatgtatt caacaaaatc ttacatcata 1850

 cagtatttat ttcttaatta atagaacttc agtgatatac ttggtagata 1900

 tctcaagcct tttgtctttt acacaatggt gctctatcct attgttttct 1950

 tttcaaagaa gcatctgaac acttgcattt ctattttcct atccaaaggc 2000

 atccacatct aagtgtgttt ttaaagttga ttaaaattat ttttctgtta 2050

 aagcattctg aaagtgtttg tctttaccta gaatgatttg tacacactcg 2100

 tggtcaactg aacatgaatg tcagtagtag tctaattatg ggaagggtaa 2150

 acgtgttaga ttaaggctct taaagctcta aaccatataa actatggact 2200

 tgtatcatga tttaactgtt cttagatctt tcttacacag tgattcattc 2250

 ctctatttgt acagtggctt tatgaaatgt tgtgaattga tactgtaatc 2300

 aataaagtgc ttttaacctc gaaaaaaaat ctatgtcggg tgcggagaaa 2350

 gaggtaatga aatg 2364

<210> 4246
<211> 11
<212> PRT
<213> Homo sapien

<400> 4246
 Leu Tyr Glu Leu Leu Leu Leu Asn Val Tyr Leu
   1               5                  10

<210> 4247
<211> 3452
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3059-3081
<223> Unknown base

<400> 4247
 gaagtttctg cgccgagtcc tccgtcggga aaactctacc aacttcccca 50

 ggggaaggga agacaacagt gtcccagctt cccgagctta gaccgcctca 100

 ccccgtaggg ggtggggcag tgggggtctg ccaccttcac cctccccgcc 150

 cgagttacgt acgccccaca aacctgaggc cgccaggggt agggtggagg 200

 gggcgggggt aagcagcctg tagtgttagc ggtggctggg accgaatgcg 250

 cgcgcgcggt gctcgaggcg gaggggagga ggcggggaag gcgaaaggag 300

 gggttcggag gagagggttc gatctccgta cgcaccaggt ggagagcgcg 350

 cgcctgggga aggaggcgtg tcgagtagcg ggagggaagt tgtagtacgg 400

 gtggggagaa ccacactaaa gggagatggg ggtgagcagt taaggaaccg 450

 cgagagcgcc aggtagagag ctgcccttaa tgggggaacc tggagaagag 500

 tgtgagcgta gtggggaaga agggagaaga caaataggtt cgggaatgtg 550

 tctccgaggg cgcgagcggg cgctaggacc cggcgtcgaa aagatgaggc 600

 tttggggctg tcggggcgcg cgctcccgtt ggtgacgcgg gggtggcgga 650

 ggtctccggc cgggacgaag ccccgcaggg agtggatact cgacagcctt 700

 cggcctccgc tcgcttctcc ctgcgcgctt tcctgctccc ctttccggct 750

 acagccctgg ggtcgagctc tggtcgaagc gcattccgcc tctcctttgg 800

 ccctgcggct tcctttgcaa cccgccgccc acccttgctc tccgtggttt 850

 acccctgggc tctgaggcct ggtggtagcg gccactgccg cggattggct 900

 gttgcggacc cggggcgggg caggtgggag aggctcgttc tccgcgggtt 950

 tcgttgtgtt tcgcgccatg tcgtttgctg agagcgggtg gcggtcggct 1000

 ctgcggcgcc gcggtcccgg caccccgggc cctgtggctc ggccatcgta 1050

 ttcctccttt actcaggggg acagctgggg tgaaggcgaa gtcgacgagg 1100

 aggagggatg cgaccaagtg gcccgcgacc tgcgggcgga gttctcggct 1150

 ggggcgtggt cagagcccag aaagcgctcg gtgctcccgc cggacgggaa 1200

 cgggtcgccc gttctgcccg ataagcgcaa tggtatcttt cccgcggccg 1250

 cgggcagcag agcccagcct cggcggtggc cggtccaggt cctctctatt 1300

 ctctgctcgc tgctcttcgc cattcttctc gccttcctcc tcgccatcgc 1350

 ctacttgatc gttaaagagt tgcatgctga gaatttgaaa aatgaagatg 1400

 atgtagacac tggactatta ggattctgga ctctacttat aatatcccta 1450

 actgctggat tctcctgttg cagcttttct tggacagtga cttactttga 1500

 ttcttttgaa ccaggaatgt ttcctcctac tcctctttca cctgccaggt 1550

 tcaagaaact gactggacat tctttccaca tgggctatag catggcgatt 1600

 ttgaatggca tcgtagctgc tcttactgta gcatggtgcc tcatgtaaac 1650

 ccacactgga gcgatattgt tggcaaaact taatcatgat tgttttgtaa 1700

 taacaagaag gagcatcact gtctactcag aagactgaga aacctgctgt 1750

 tcattatgta gttcagatat ttatcacaat catcctcatt atggaagacc 1800

 ttttaaagca ttgttttaga atgtctgagt attaagatac agattaattg 1850

 ggaatatctg agtattaagt actttcttca gagtataaga tgtttacctc 1900

 atctttttac ttttgtgtgt gtagttcttt caagttgtag gaaacatttt 1950

 aatggaattt aaactcaaaa acttgaatac aggacaatgc ttgccttttc 2000

 atgtatgtac tacatttttt gctaagaaat actgatattt ctgtttagtt 2050

 gagctagaaa tacttcttat ttatacattt aggaaagcaa ataatgccta 2100

 ctactccgac ttttatagaa gctactttta aatcagaata tttaattttt 2150

 gatattcata taattaatag aagttgcatt tatatttttt atggggcata 2200

 gttccttatg tgttttttta atgtattttc atactacata ctgaatttgt 2250

 atgtttttaa aattgttaca tctagacaac tgtaaacatt atttttttag 2300

 ctagtgcaaa cctagtacct gccattttta ctaatttttg tctttaaaaa 2350

 aagcaaaaaa gcacattgac ctaagttgaa aattaagtaa gtttattttt 2400

 aacaaaaaat gcctgaaaaa agctaaatta tttaagtcat taagatattg 2450

 agaaaaaatt tgaaattttt actatttctg tttccacaat tccaaatatt 2500

 tatcttggtg tatatattgt tactttaaca gaacttgcat tattttgttt 2550

 ttaataaata taaacatgaa atttttgtat gtgagaatga ttgaactagt 2600

 ttgttcttaa tctcaaaaat ttagttacca aagtagaaaa ggtattttga 2650

 tactagatat taaaaactac atatagttaa tataatttta taatttttgt 2700

 aattaaatgt gcttctgtaa ttgtgatatt ttgttttcta agtaattaag 2750

 ccttaatttt tcccctatgt tactaaagac ttttaatgtt tagaaagtta 2800

 cctcagtttt agaaagatgg actacttaca aagctgtttt ccctggccat 2850

 aggaaaactt acaataagaa accattaagt agtcaaactg cttattcagg 2900

 ctaagtggga aatgaatttg tgcagtgtgt tcccttaatt atctactgaa 2950

 tgttgttacc gactaaacaa ggtttctaaa agtctcgcat ttcttttact 3000

 attcaaaact ctttgcgttg gaaatgacta atactgctcc aatttaaatt 3050

 atctgaaann nnnnnnnnnn nnnnnnnnnn naaatatcaa tcccatggct 3100

 taagtattcc taccagagtg gtggttgcca tcagtctatt ttcactccct 3150

 gccttccttc ctgcacgctt aaactcttca ccctttgact ccaaagagcc 3200

 ctttcattgc aaagatgtac acaagtaaca gaatcaattt atcttctctc 3250

 caccactctg tattcccacg caccaccaat gtgagtaact cgctccagat 3300

 tgtttgtgtc taatgactag gaaagttatt aacagtagac cctagataga 3350

 gatatgtaca ccctagacag tcatgtgcca tataacaacg ttttggtcac 3400

 aacgaactgt acttatgata gtgaatcccc ccgtaagatt atactgctgc 3450

 at 3452

<210> 4248
<211> 226
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3059-3081
<223> Unknown amino acid

<400> 4248
 Met Ser Phe Ala Glu Ser Gly Trp Arg Ser Ala Leu Arg Arg Arg
   1               5                  10                  15

 Gly Pro Gly Thr Pro Gly Pro Val Ala Arg Pro Ser Tyr Ser Ser
                  20                  25                  30

 Phe Thr Gln Gly Asp Ser Trp Gly Glu Gly Glu Val Asp Glu Glu
                  35                  40                  45

 Glu Gly Cys Asp Gln Val Ala Arg Asp Leu Arg Ala Glu Phe Ser
                  50                  55                  60

 Ala Gly Ala Trp Ser Glu Pro Arg Lys Arg Ser Val Leu Pro Pro
                  65                  70                  75

 Asp Gly Asn Gly Ser Pro Val Leu Pro Asp Lys Arg Asn Gly Ile
                  80                  85                  90

 Phe Pro Ala Ala Ala Gly Ser Arg Ala Gln Pro Arg Arg Trp Pro
                  95                 100                 105

 Val Gln Val Leu Ser Ile Leu Cys Ser Leu Leu Phe Ala Ile Leu
                 110                 115                 120

 Leu Ala Phe Leu Leu Ala Ile Ala Tyr Leu Ile Val Lys Glu Leu
                 125                 130                 135

 His Ala Glu Asn Leu Lys Asn Glu Asp Asp Val Asp Thr Gly Leu
                 140                 145                 150

 Leu Gly Phe Trp Thr Leu Leu Ile Ile Ser Leu Thr Ala Gly Phe
                 155                 160                 165

 Ser Cys Cys Ser Phe Ser Trp Thr Val Thr Tyr Phe Asp Ser Phe
                 170                 175                 180

 Glu Pro Gly Met Phe Pro Pro Thr Pro Leu Ser Pro Ala Arg Phe
                 185                 190                 195

 Lys Lys Leu Thr Gly His Ser Phe His Met Gly Tyr Ser Met Ala
                 200                 205                 210

 Ile Leu Asn Gly Ile Val Ala Ala Leu Thr Val Ala Trp Cys Leu
                 215                 220                 225

 Met


<210> 4249
<211> 5730
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 305, 313
<223> Unknown base

<400> 4249
 aacttctatt ttttcttgat aattctgtag gcaaaaaaat tggggaaggc 50

 aaattacaat cattcttctt ctgtaatact ttgggacaat ttttaaacaa 100

 ctcagaccca tgtttaaaaa cgagttttgt gtgattaacc cttgtatagt 150

 atccagttac tgtcttctct tgaagtggtg gttctttgag aagtagaatt 200

 attttgtaac ttttcttctc ccagaaacag aagaatcaaa tactattctg 250

 ttaggattct atctagacct gtgactctta gtataataac ccttttatta 300

 ttatnattat ttnttttttt tcagtaatct ataaagtaga gttgcttagt 350

 tttgagcaat ttagggcttt tcttattggc cagtaggtta ttcattttgc 400

 tgctaaatat aattttttgg ttaattttaa cattatagtg ctggccgctg 450

 ggttctatga ttacctaaaa atctagtttt tttcctccat aggtagatgt 500

 gtgtgtatgc atacccccac acacacacgt acatatatgt tgtcatagag 550

 aggtatttca acccttattt caaataacag tagaagatac gaacatgaat 600

 ttatatttgg taaaaatgtc attcatccac ttggtttccc attggaaata 650

 gttttataag aagggttccc cctgtgctct ctccacttaa caatttcatt 700

 atatacgtag aaaaagcagc cgacttaagg gcttgatgtt ttttcaggcc 750

 ttgtggattc aggtttccag tttcccagtg cccttaatgg atgttatgaa 800

 tgcataagca cattttcttt taaagaaaga agttagattt atagtgttat 850

 ttcttacttg ctatatttct ttgcactaaa aaagagctat gtgtttgttt 900

 tataggacac tttagtaccg tattgcctac aataactcag tttgctcctt 950

 aaattccaaa ctctgggaag ttgataaata acttccatga tcacttgtaa 1000

 aagttacatg cacatctgaa aaaaaatcac aaatctctat gacagtaggt 1050

 tatgttttga gcttgttacc ttgcagtatt cttctctgtt ccataggtga 1100

 aaacaaaggg tgacagaggt tatcaggcag gaaatgccta aatacataca 1150

 tctctgcatg gtacaatttc tcatattcat gtattccata aacagtgttt 1200

 tttctctgtt taagcagact gttgtttctt ctgagtcagt gatatgtgat 1250

 cttcgttggt ttcattttgt gaagctcagt ctgtctctgt aacatacttt 1300

 aggatttgca ccttgtgctc cccaggaatt atgttagtgt ccttttctat 1350

 gctgtcttca aggatggaca gaggcctaaa ccacaacaac aacaaaaatt 1400

 agaaaaaaaa atacttagat ttcggtaatc atccatagga actcatagca 1450

 tcagtctctt ttctctgtga ataatatctt tgtgtaagtt gtcataaaaa 1500

 atcaacgtta gaagatgaca attagaattc ttcttaggta ttgagggtaa 1550

 gaagttgtaa agaaagaaaa ttcgtgtttc aactaaaaga ttggattgca 1600

 tatacctttg aagtggtttt gtaaaaaaag ttcagttact aaactgagtg 1650

 tgccctgtaa tccttttgag tgcactgaag atgctttgaa aatactttgt 1700

 tggtcttcac attgtgcatc atgtcctgca acttgtaaat atgtgcatgt 1750

 tgtttatgtt tgtctgcctg tctcttattg cactaaattc tgcaaggtga 1800

 ataatttttt tataccattt atttggaaaa agttcctcct ccaactcttc 1850

 ttcactgacc ttttaattag ttggtaaact tagaaaacca ggtaggattt 1900

 ttgaagccct gagtttaaaa gaagaatcgt ggctatttga catcatcctt 1950

 acattcccct gacttaaaaa gctaacaaga agcacgagat cttccacctc 2000

 attttagaaa gcttttctac agaactatat gcttgcttat agctacctat 2050

 ctacagtttg aacagggaga aagggagata tgtatgtctg gttacatctt 2100

 ccttcactct tgaattggct gggacagcaa gcaacaacag tttgaggtcc 2150

 agtgacctac gtaaaatgag tgtcgtttgt gtcaggggac acatgtaact 2200

 gtgcaacatg gtattttcta cagggagggc taggaagggt ggttttggaa 2250

 cctaacctac tttgtgtctt cattgtcaga actaaggttg gaaatgccct 2300

 ttaaaggact tggtgaggca tatgctagga caatagagct gctttagaaa 2350

 gaaattgaga catgttttgt caggacagat aaaagtttaa tgcaggcttt 2400

 tgaacagatg ttttaaaaca aatttgacct taccaactat ttttttcttc 2450

 tagccaaatc attgtacagg agtttcatat atgataaaaa gtgttttgtt 2500

 attgtttttg ctttcttggc aggggagaac ccctaccatt gtgagcagtt 2550

 actgtcactc tggctgaatg gacaaatagc tgtgtaaata gcttctcata 2600

 aaacgcttct actgatagct gtttgacttt ttcttcccgt tatgaatggg 2650

 aggaacattt gtaaacttcc tttctgggta gctaccaaaa aacgtactgg 2700

 cttatggtcc catgtgacct tgtctccgtt aagcccagaa tctgagtgcc 2750

 tttagcaagt gttagcattt cacagagaga agagagacag aattattgct 2800

 attaatcacc attcataaat aggagcttgg aataacaaag gtctgtgtga 2850

 attctgttct acgtcttttt tttccctttt ttaaataaat gtcaatttga 2900

 tatcaagtaa aactattgtc attattgatc agaaaccata cattctgaaa 2950

 atgaatccag ttttcccaag ctggcagaag tcagagatca tttttcacct 3000

 tgatctgtgt tgcgtttgta cttagtgaat ggcagtgtgg ttgattggaa 3050

 gagcttgaca ctgatgtttg gaaaaattct ttattctagt ggtcattttc 3100

 aaacttgtct tctgtagaga ggggaaaaat tatgtatttg cagctaaagc 3150

 gaagagactg gcacaataat tattaattgt gttagttcat ttctatatta 3200

 aatgaagcat cttcacaaat caggtttgaa gccattaaaa gcaaaatttt 3250

 ccctagttta attaatttaa aattctaaat tgcctgacta cttagaatct 3300

 tagaaacgcc ctgctagact gattttatta tagaaatgtt aacatgttcc 3350

 tcaacatttt ctcaagaaaa ttttcagaca tatatcaaag ttgaaaaaac 3400

 tttgcagtat aaccactgct agattctgcc atcaacattt gactatactt 3450

 gtattgccat gtatctgttc atattctcta tccctctttt catccatcga 3500

 tccatcagat ttttttttta aagaacattc caaagtaaat tttaggcaat 3550

 acactgccct aaattcttag catgggtgtc attaattaag gtttagtatt 3600

 cgtttaaata tctattttga aagtggtgta tgaagttgat aatctgagcc 3650

 aattaacata cttttttttt tttcctcctg tggacttttg tcttccagtt 3700

 tctctttttg tgtgtactta gggtgaggga ggacaattcc tttcaaacac 3750

 aagtttattt tagaattggt catttttaag tgcttgtcat aaattttaaa 3800

 gtttcaatat aatttttctt ttccccactt ctgataatgt atttttgcca 3850

 aactatgcag cttcttcaaa aaactgtaaa ttactgattg gggtttatga 3900

 aatcagcgaa tacctcattt caatctgttg ctgcttttct ccctcttgtc 3950

 acttctcctt tcactacttt cagctgctct accagaaggt agaggggagt 4000

 aaagggtcaa acccctatat aattagctgt tttaaacaac tctaggagag 4050

 cagattaagt agcttagtaa gttgaaacta ttaatttttc taaagaattt 4100

 gatttgaatt ccttgagaat tgtaattatc cacacttcct ccagctataa 4150

 ttagcagaat taaaaatgat tgtactgtac aatgagttgt tgaaattgta 4200

 agccttagta accatcttta gctttattgt agtcatgttt agaaaaaatt 4250

 atttttacat atgcctttat ttttatgccc actttttgtg gataagattc 4300

 tttagataaa atctaaagaa ttttaagtga ctttctccag gtcatgaaga 4350

 ttcaatgggt agaattgaat cagaattgaa atgttccaga ttcatattct 4400

 tgtgtgtgtt tgataaaatt catggcttcc aaagtaactg aacacttcct 4450

 ttgggccctt ggagggaaaa tccatatttt tactaattac actttttttt 4500

 ttagacatct ggcagttctt tgaacttaaa catattctca tggccatagt 4550

 tccaaattaa gcccgacgca gttgctaaaa atcttgctgc actgttgaat 4600

 actaataatg caacatttat tggatgtttt tgcattttga tgaccttcat 4650

 gattcattta taagtctttg taagtgctta agtgaccccc tcactagtga 4700

 aaataataaa tgttctatat catttattat tatttgtgta ttctctacat 4750

 gatatatttt tttaaggaag agtaactcca catgtcagaa tgagtgatat 4800

 tatcctaggg caaagcgcaa atagggcagt ttgtttctac tctgcaaata 4850

 tggcatgtat aggaacaaaa ctcttttgga gtggctggtc attgttttgc 4900

 cctcttttgg tacctgagta cctttctggg gttttgtaaa tcgtgtgtca 4950

 tttgtaagaa tttcacgtta actctgcgtt acttggtgtt cacctgtggt 5000

 atccttgact gaccataatg atttagtttg ggtatgatgt gtctgctttg 5050

 aaatgcctta ctggagtatg tcagatcctg ctttaaagca ttccatatat 5100

 ctgctgggac aataagttgc ttctccttgg aaatatgctc tagattcaga 5150

 agcaaaaccg attttgcttt caccattaag gttgcatttt aatgcagtta 5200

 ttgttttaaa ttagagaata aaatgtaaaa ccaagggagg ctttagaacc 5250

 ctttattgaa tggcatggca aacttttaaa actgcttttg ctatttcact 5300

 agaactatct ttgataaagg atatagctaa aaaatgtcag cccaaactgt 5350

 gtgtaattag ggttgtttat taaaattttc tctaaatgtc atacagaggc 5400

 ttaagatctg tgtatgctgt tgggtcggag tgccagtcac tgctttggaa 5450

 gtctgtgttc tggggctgca gaatgacaaa cgtgtcatgg gattaaaacc 5500

 aatcaactgt gaattgtgaa attgaaacta ctctttcggt tttattttct 5550

 ttagcatatt gagtatagaa atctgaaact tatttaaaat ttatactgct 5600

 tttgttgatg gctcattttg gctgtgtatc ctcacttatg tactgatttc 5650

 tgataaaggc ttgacattat tataacacgc attttgtgtt ccagtttaat 5700

 aaaacggttt ctgagtcttg tctgaaaaaa 5730

<210> 4250
<211> 43
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 305, 313
<223> Unknown amino acid

<400> 4250
 Leu Leu Phe Phe Leu Asp Asn Ser Val Gly Lys Lys Ile Gly Glu
   1               5                  10                  15

 Gly Lys Leu Gln Ser Phe Phe Phe Cys Asn Thr Leu Gly Gln Phe
                  20                  25                  30

 Leu Asn Asn Ser Asp Pro Cys Leu Lys Thr Ser Phe Val
                  35                  40

<210> 4251
<211> 6512
<212> DNA
<213> Homo sapien

<400> 4251
 agcgacgcaa ggtcggctgc ggcggcggcc cgagggcgcc cgtgtgccca 50

 gtgcgcggcg gggacggccg cgagctcgct ggagggctcc ccagaataat 100

 ccagaagtcg attccatcat ggcagaactc aaggtggagg cgccggccag 150

 cgtagactgg cagaaacgct gcctgaccct ggaaactcag cttttccggt 200

 tccgcctaca ggccagcaag ataagggagc tgctggctga caagatgcag 250

 gagctggagc agaggctgct ggaggcagag cagagagcag agaacgctga 300

 gacccaggtg ggtgtcatgg aagagaaggt aaaactatcc aatctgaaga 350

 atgtggactc tgaggggagc ctgcaccgga aataccaaga attgctgaaa 400

 gccataaagg gcaaagatga gctcatcagc cagctagagg ctcagctgga 450

 gaagcagaag cagatgaggg cagaggaagc aaaaactgtt caagaaaaag 500

 ctgcaaagat caaggaatgg gtgacactca agttggcaaa gcttgagatg 550

 gagaatcagc atctgaaaag ccataatcag cgcctggtgg agcaggtggg 600

 atcccttcaa gatgcgctag aagctattca gatagctcct tcacggaagc 650

 tgctggtgcc cccctacgga gctgcagagc aggattctgt cccttcagag 700

 ccgggaatcc agcctatggg ccaggacagt ggctcccagg cccagggtct 750

 gaaggcagct gtgcttgcac cttccccagg tgccctgcag agcaaggact 800

 ctgtttctga agcagcaagc cccttggagg attctagttc cagcacggtc 850

 cattctgggg aaacagtaga ggccaagccc cttcaacctc atctgggaag 900

 agagagccct ccccaccagc catgcatgaa gcttcttacc ttcagatgta 950

 gttcagcttc ctggggtgag ggtctggtta ctgctcagag agggatgctc 1000

 cctgggacaa agacctctgc cagggaaggt ggtcctggca gcagtctgac 1050

 cctaccaaag gtgcgggctc ctggcacccc gcgggacagc atccagttgg 1100

 ccaaaaggca ccacagccag ccccaggtgg gccatgggca ctttggccgt 1150

 gtggtaaaca ttgagactga ggccttctca gccctccacc cctctggcct 1200

 tcctgagctg gagtcccgag ctaggtcccg ggaggaacca gagaagatgg 1250

 agatggagga gccaccccca gcagggaaga atgaggaaag agagagccca 1300

 aaggcccttg gagctgagct ggaggaagtg gagctgggta acaagccacc 1350

 tacacccccg ctgcaccagt tttcatcctg ggagagccgg atctatgctg 1400

 tggccacatc gggcatgcgg ctctcagata tgtctcccag aagtaatact 1450

 gcatgctgcg cttcaagccc tcctgccctt gtttcccctg ggtctttctc 1500

 tggcctggtc tacaagaatg tcactgtgcc tgtctacaca gcactgaagg 1550

 ggagagctac acagatcagc aacatgccct ttatggacga gtcctctggg 1600

 tctgacgatg actgcagctc tcaggcgagt ttccgaatct cggtcccctc 1650

 ctctgagtcc aggaagacca gcggactagg cagcccccgg gccatcaaga 1700

 gaggcgtctc catgtcctca ctgagctccg agggtgacta cgccatcccc 1750

 ccggacgcct gctcactgga cagtgactac tcagagcctg agcacaaact 1800

 gcagcgcacc tcatcctact ccaccgacgg gctgggcctg ggcggggagt 1850

 cactggagaa gtcgggctac ctgctgaaaa tggggagcca ggtgaagacg 1900

 tggaagaggc gctggtttgt cctgagacag ggacagatta tgtactacaa 1950

 gtccccgagt gatgtcatcc ggaaacctca aggccaagtg gatctgaact 2000

 cccgctgcca aattgttcga ggggagggtt cacagacgtt tcagctcatc 2050

 tctgagaaga aaacctacta cctgacggcc gattcaccca gcctgctgga 2100

 ggagtggatc cgagtactcc agagcctgct gaaggtgcag gccaccgggc 2150

 ctccagctct gcttcggggt ggcaccaagc ccaccgtgaa gggctggctg 2200

 accaaggtaa agcatggcca ctccaaggtg gtctggtgcg ctcttgttgg 2250

 gaaaatcttc tactactatc ggagccatga ggacaagcga cccctgggct 2300

 gcctgcctgt gcgggatgcg cacatagagg aagtagatcg atcctgtgac 2350

 tcagacgagg actatgaggc tggaggaacc agacggttgc tttcctccca 2400

 ctgcaccctg gtgatccacc ccacagagca cagccccacc tacctcctca 2450

 ttggcaccaa gcatgaaaag gatacgtggc tctaccacct cacagtggct 2500

 gcaggtggca gcagtgccaa ggtgggcact gcctatgagc agctcattgg 2550

 aaaactgatg gatggtgaag gagatccaga ttcgccgctc tggaggcacc 2600

 ccatgctgtg ctacagcaaa gacggcctat acgcctccct caccaccctg 2650

 ccctctgagg ccttgcagac ggaggccctc aagctcttca agtcctgcca 2700

 gctcttcatc aacgtgccgg tggaagctgc ctcggtggac taccatgtgt 2750

 ccctggccca gaccgcactg caggtctgcc tggttcaccc cgagctgcag 2800

 agtgagatct actgccaact catgaagcag accagctgcc gcccacctca 2850

 gaagtactcc ctcatgcagt gctggcagct cctcgctctg tgtgctccac 2900

 ttttcctgcc tcagcatcac ttcctctggt atgtcaagca gcagctccaa 2950

 cgccatgcag atcccagaag tgaaactggc cagtatgcca cctactgcca 3000

 gcgggcagtg gagcggaccc tgcggaccgg ggagcgggaa gccaggccat 3050

 cgcgcatgga agtggtgtcc atcctgctgc gtaacccctt ccaccactcc 3100

 ttgcccttca gcatccccgt gcactttacc aacgggactt accatgtggt 3150

 tggttttgac ggctcttcca cggttgatga gttcctccag cggctgaacc 3200

 aggagatagg catgagaaag ccatcccact ctggctttgc cctcttcacg 3250

 gacgatccct cgggcaggga cctggagcac tgcctgcagg gaagtgtcaa 3300

 gatctgtgat gccatctcca agtgggaaca agccatgaag gagctgcacc 3350

 ccggaaagtc tgagggtggg acacgcgtcg tgaagctgat gtacaagaac 3400

 aggctgtact ttcgcagtca agtcaaaggg gagacggacc gagaacggct 3450

 gctccttgcc tctcaaacca gtagagagat agtggcaggg aggtttccta 3500

 tcaacaagga attggctctt gagatggctg ccctgatggc ccaggtagaa 3550

 tatggggact tggagaagcc tgccctgcca ggccctggag gcacatcccc 3600

 tgccaaggct cagcatcttc tccagcaggt cctagacagg ttccacccca 3650

 ggcgctatag acatggggcc cccgctgaac agctgaggca cctggcagat 3700

 atgttgacca caaaatgggc aacattgcaa ggatgctccc ctcctgagtg 3750

 catccgcatc tacctgaccg tggccaggaa atggcctttc tttggtgcta 3800

 aactttttgc tgctcagcct gcccagctgt cttccaagga gaacgctctg 3850

 gtgtggattg ctgtgaatga ggatggcgtc agcatcctgg accacaacac 3900

 tatgcaagtg cacatcactt acccctactc ttcagtgaca acgtttggtg 3950

 gctgcaggga tgacttcatg cttgtgatta gatctatccc agacaagagc 4000

 tctggaaaaa gccacattga gaagttgatc ttccggatgg ctgctcccaa 4050

 gattgcagaa gccaccttca tcatggccag ctatatgaac cattgcacta 4100

 caactgtgaa cccccccacc aacccacccg gagcctgcca gctgtgggaa 4150

 ctggatggac gacagttctt ttcttctgtt tcctgtgcta ccaaggggcc 4200

 aacgttgctg tgaatatttc tcctacccga ttccccacca ccactagtgc 4250

 ctctggattt agagatatat atcctagggt atgatactac tgtgacgggt 4300

 ctaacagccc ccggctactc ttgttctgtg aaatgtgtat tttagtctct 4350

 gtgaagcctt tactctctag gtgccttata atgtttcagg gctcaacttt 4400

 ttaaaatcca gacccagtgt taaaaccatt tattcctttt ttcataagaa 4450

 taatgactcc agatgctacc tgattctaga catagacagg gatgatccac 4500

 tgttactgag ggcatcagtg ctataagtta aggctttctg cactggtact 4550

 ctcaaggaag ctaattttct ttctgggggg ggcgggggac acagtgtcac 4600

 tatgtcaccc agtccacagg gttcaagcaa ttctcctgcc tcagccttcg 4650

 gagtagctgg gattacaggt gtgcgccacc atgcccggct aatttttgta 4700

 tttttagtag agacggggtt tcaccatgtt ggccaggctg gtctcgaact 4750

 cctgacctca ggtgatctgc ccactttggc ctcccaaagt gctgggatta 4800

 caggcatgag ccatcgccca gcccagaagc taatttttta atattgtata 4850

 tggtcttatt tatacttgaa gttttgtgaa cgtcgctaaa caggatagga 4900

 ctaaaatttc caattctcct acactctgtc agaagcctag aactcactaa 4950

 actgggctgc ctttcccaaa tgggaaaggt gctgacagag ttggagaaaa 5000

 aagaatagac tcatttttcc ccattattgg tatgtaggca ttggtacagc 5050

 cccttctggg gcagtctttg caggataaca tgctatacct gctaagattc 5100

 aagctgtttt cctcacactg gactttaggc caaacccagt accacgcaat 5150

 gtgcaagcaa gggcaggagg taggtccaat ctgacccctc cctgtctcat 5200

 tttaatgact ggacagcgct cggtgaaggc tgtgttcact gtagtgggcc 5250

 atcatttgtt tccttcttct tgtaaaagac caagcaaatg cactctgctt 5300

 tttgctgctg taagaccacc aaaaatgagt cagaaacaca gaagactatt 5350

 tcaggcatgt gggcctggat atgctccttg agacttctgg caaacttctg 5400

 ctgggaatta gtttgagggt gagggtacat atgtgacatt tgccctagcc 5450

 taagagtagc aggtaaaaaa aagtttcttt catcctttgc cttactgata 5500

 ataccataat ccccctcaat tcagaccttc tgattgagtg cagaggagac 5550

 tagacagtct cctctagaca ggttgtagac acaccctccc ctaacaaaaa 5600

 caaaacgaaa gagttcatac tctgattttc caacatctag gaaactgagt 5650

 tttatttcct agctctaagg cagccttact atatgtcagt aaagtgctga 5700

 aaactgtata tttagcagta gcacccaaaa ccaagccttt aaccccaaca 5750

 atgtgtgtat cttttgcaca gcaaaaactg cgaggccaga actagtttat 5800

 ctgaacacct cagctgctgt aagcttctcc tctctcaccc cgtaaactga 5850

 caagcatgat gaaaaaagaa gcacatccaa gtttctgcct cttttaaatg 5900

 tacttgactt tgcaaggcaa gtagttttac agccatttct gttcacactt 5950

 ttcaccccac aacttgggga tctagctgag acatttctac ctcgaacaag 6000

 tcacatgtac cacaggttcc tgaataattc ctgcagggct ggtgacagac 6050

 ataacagctc tggttttata atatcttggg tatctctaag gccaataagg 6100

 ataacattat ctacccagag agtttagaag aaaagtagga gtccaaagga 6150

 agagtaaaca agaatggagc tgtgttcaca ctgaatttgg ggtcaatcta 6200

 tttcccccac cctctctcct ccccaaccct tcaggaaccc tttagtttat 6250

 taatcttata cagaagaaac taacttagaa acaaaggatt caatatttgc 6300

 ttatttattc tttgttaaca tgagagtccc atgtctgaaa accaaagtcc 6350

 aatttctgtc tggccttttg tctcatcctt cttggcaaaa gtagcttttg 6400

 aactgatata aaaaaaaatg ctgagtaaca gaaaagtatt aatgtgcttg 6450

 acaccatgac tgaaatacta tgatcttgtt tgtcaataaa aagcagctat 6500

 ctgtgaacca gg 6512

<210> 4252
<211> 1403
<212> PRT
<213> Homo sapien

<400> 4252
 Ala Thr Gln Gly Arg Leu Arg Arg Arg Pro Glu Gly Ala Arg Val
   1               5                  10                  15

 Pro Ser Ala Arg Arg Gly Arg Pro Arg Ala Arg Trp Arg Ala Pro
                  20                  25                  30

 Gln Asn Asn Pro Glu Val Asp Ser Ile Met Ala Glu Leu Lys Val
                  35                  40                  45

 Glu Ala Pro Ala Ser Val Asp Trp Gln Lys Arg Cys Leu Thr Leu
                  50                  55                  60

 Glu Thr Gln Leu Phe Arg Phe Arg Leu Gln Ala Ser Lys Ile Arg
                  65                  70                  75

 Glu Leu Leu Ala Asp Lys Met Gln Glu Leu Glu Gln Arg Leu Leu
                  80                  85                  90

 Glu Ala Glu Gln Arg Ala Glu Asn Ala Glu Thr Gln Val Gly Val
                  95                 100                 105

 Met Glu Glu Lys Val Lys Leu Ser Asn Leu Lys Asn Val Asp Ser
                 110                 115                 120

 Glu Gly Ser Leu His Arg Lys Tyr Gln Glu Leu Leu Lys Ala Ile
                 125                 130                 135

 Lys Gly Lys Asp Glu Leu Ile Ser Gln Leu Glu Ala Gln Leu Glu
                 140                 145                 150

 Lys Gln Lys Gln Met Arg Ala Glu Glu Ala Lys Thr Val Gln Glu
                 155                 160                 165

 Lys Ala Ala Lys Ile Lys Glu Trp Val Thr Leu Lys Leu Ala Lys
                 170                 175                 180

 Leu Glu Met Glu Asn Gln His Leu Lys Ser His Asn Gln Arg Leu
                 185                 190                 195

 Val Glu Gln Val Gly Ser Leu Gln Asp Ala Leu Glu Ala Ile Gln
                 200                 205                 210

 Ile Ala Pro Ser Arg Lys Leu Leu Val Pro Pro Tyr Gly Ala Ala
                 215                 220                 225

 Glu Gln Asp Ser Val Pro Ser Glu Pro Gly Ile Gln Pro Met Gly
                 230                 235                 240

 Gln Asp Ser Gly Ser Gln Ala Gln Gly Leu Lys Ala Ala Val Leu
                 245                 250                 255

 Ala Pro Ser Pro Gly Ala Leu Gln Ser Lys Asp Ser Val Ser Glu
                 260                 265                 270

 Ala Ala Ser Pro Leu Glu Asp Ser Ser Ser Ser Thr Val His Ser
                 275                 280                 285

 Gly Glu Thr Val Glu Ala Lys Pro Leu Gln Pro His Leu Gly Arg
                 290                 295                 300

 Glu Ser Pro Pro His Gln Pro Cys Met Lys Leu Leu Thr Phe Arg
                 305                 310                 315

 Cys Ser Ser Ala Ser Trp Gly Glu Gly Leu Val Thr Ala Gln Arg
                 320                 325                 330

 Gly Met Leu Pro Gly Thr Lys Thr Ser Ala Arg Glu Gly Gly Pro
                 335                 340                 345

 Gly Ser Ser Leu Thr Leu Pro Lys Val Arg Ala Pro Gly Thr Pro
                 350                 355                 360

 Arg Asp Ser Ile Gln Leu Ala Lys Arg His His Ser Gln Pro Gln
                 365                 370                 375

 Val Gly His Gly His Phe Gly Arg Val Val Asn Ile Glu Thr Glu
                 380                 385                 390

 Ala Phe Ser Ala Leu His Pro Ser Gly Leu Pro Glu Leu Glu Ser
                 395                 400                 405

 Arg Ala Arg Ser Arg Glu Glu Pro Glu Lys Met Glu Met Glu Glu
                 410                 415                 420

 Pro Pro Pro Ala Gly Lys Asn Glu Glu Arg Glu Ser Pro Lys Ala
                 425                 430                 435

 Leu Gly Ala Glu Leu Glu Glu Val Glu Leu Gly Asn Lys Pro Pro
                 440                 445                 450

 Thr Pro Pro Leu His Gln Phe Ser Ser Trp Glu Ser Arg Ile Tyr
                 455                 460                 465

 Ala Val Ala Thr Ser Gly Met Arg Leu Ser Asp Met Ser Pro Arg
                 470                 475                 480

 Ser Asn Thr Ala Cys Cys Ala Ser Ser Pro Pro Ala Leu Val Ser
                 485                 490                 495

 Pro Gly Ser Phe Ser Gly Leu Val Tyr Lys Asn Val Thr Val Pro
                 500                 505                 510

 Val Tyr Thr Ala Leu Lys Gly Arg Ala Thr Gln Ile Ser Asn Met
                 515                 520                 525

 Pro Phe Met Asp Glu Ser Ser Gly Ser Asp Asp Asp Cys Ser Ser
                 530                 535                 540

 Gln Ala Ser Phe Arg Ile Ser Val Pro Ser Ser Glu Ser Arg Lys
                 545                 550                 555

 Thr Ser Gly Leu Gly Ser Pro Arg Ala Ile Lys Arg Gly Val Ser
                 560                 565                 570

 Met Ser Ser Leu Ser Ser Glu Gly Asp Tyr Ala Ile Pro Pro Asp
                 575                 580                 585

 Ala Cys Ser Leu Asp Ser Asp Tyr Ser Glu Pro Glu His Lys Leu
                 590                 595                 600

 Gln Arg Thr Ser Ser Tyr Ser Thr Asp Gly Leu Gly Leu Gly Gly
                 605                 610                 615

 Glu Ser Leu Glu Lys Ser Gly Tyr Leu Leu Lys Met Gly Ser Gln
                 620                 625                 630

 Val Lys Thr Trp Lys Arg Arg Trp Phe Val Leu Arg Gln Gly Gln
                 635                 640                 645

 Ile Met Tyr Tyr Lys Ser Pro Ser Asp Val Ile Arg Lys Pro Gln
                 650                 655                 660

 Gly Gln Val Asp Leu Asn Ser Arg Cys Gln Ile Val Arg Gly Glu
                 665                 670                 675

 Gly Ser Gln Thr Phe Gln Leu Ile Ser Glu Lys Lys Thr Tyr Tyr
                 680                 685                 690

 Leu Thr Ala Asp Ser Pro Ser Leu Leu Glu Glu Trp Ile Arg Val
                 695                 700                 705

 Leu Gln Ser Leu Leu Lys Val Gln Ala Thr Gly Pro Pro Ala Leu
                 710                 715                 720

 Leu Arg Gly Gly Thr Lys Pro Thr Val Lys Gly Trp Leu Thr Lys
                 725                 730                 735

 Val Lys His Gly His Ser Lys Val Val Trp Cys Ala Leu Val Gly
                 740                 745                 750

 Lys Ile Phe Tyr Tyr Tyr Arg Ser His Glu Asp Lys Arg Pro Leu
                 755                 760                 765

 Gly Cys Leu Pro Val Arg Asp Ala His Ile Glu Glu Val Asp Arg
                 770                 775                 780

 Ser Cys Asp Ser Asp Glu Asp Tyr Glu Ala Gly Gly Thr Arg Arg
                 785                 790                 795

 Leu Leu Ser Ser His Cys Thr Leu Val Ile His Pro Thr Glu His
                 800                 805                 810

 Ser Pro Thr Tyr Leu Leu Ile Gly Thr Lys His Glu Lys Asp Thr
                 815                 820                 825

 Trp Leu Tyr His Leu Thr Val Ala Ala Gly Gly Ser Ser Ala Lys
                 830                 835                 840

 Val Gly Thr Ala Tyr Glu Gln Leu Ile Gly Lys Leu Met Asp Gly
                 845                 850                 855

 Glu Gly Asp Pro Asp Ser Pro Leu Trp Arg His Pro Met Leu Cys
                 860                 865                 870

 Tyr Ser Lys Asp Gly Leu Tyr Ala Ser Leu Thr Thr Leu Pro Ser
                 875                 880                 885

 Glu Ala Leu Gln Thr Glu Ala Leu Lys Leu Phe Lys Ser Cys Gln
                 890                 895                 900

 Leu Phe Ile Asn Val Pro Val Glu Ala Ala Ser Val Asp Tyr His
                 905                 910                 915

 Val Ser Leu Ala Gln Thr Ala Leu Gln Val Cys Leu Val His Pro
                 920                 925                 930

 Glu Leu Gln Ser Glu Ile Tyr Cys Gln Leu Met Lys Gln Thr Ser
                 935                 940                 945

 Cys Arg Pro Pro Gln Lys Tyr Ser Leu Met Gln Cys Trp Gln Leu
                 950                 955                 960

 Leu Ala Leu Cys Ala Pro Leu Phe Leu Pro Gln His His Phe Leu
                 965                 970                 975

 Trp Tyr Val Lys Gln Gln Leu Gln Arg His Ala Asp Pro Arg Ser
                 980                 985                 990

 Glu Thr Gly Gln Tyr Ala Thr Tyr Cys Gln Arg Ala Val Glu Arg
                 995                1000                1005

 Thr Leu Arg Thr Gly Glu Arg Glu Ala Arg Pro Ser Arg Met Glu
                1010                1015                1020

 Val Val Ser Ile Leu Leu Arg Asn Pro Phe His His Ser Leu Pro
                1025                1030                1035

 Phe Ser Ile Pro Val His Phe Thr Asn Gly Thr Tyr His Val Val
                1040                1045                1050

 Gly Phe Asp Gly Ser Ser Thr Val Asp Glu Phe Leu Gln Arg Leu
                1055                1060                1065

 Asn Gln Glu Ile Gly Met Arg Lys Pro Ser His Ser Gly Phe Ala
                1070                1075                1080

 Leu Phe Thr Asp Asp Pro Ser Gly Arg Asp Leu Glu His Cys Leu
                1085                1090                1095

 Gln Gly Ser Val Lys Ile Cys Asp Ala Ile Ser Lys Trp Glu Gln
                1100                1105                1110

 Ala Met Lys Glu Leu His Pro Gly Lys Ser Glu Gly Gly Thr Arg
                1115                1120                1125

 Val Val Lys Leu Met Tyr Lys Asn Arg Leu Tyr Phe Arg Ser Gln
                1130                1135                1140

 Val Lys Gly Glu Thr Asp Arg Glu Arg Leu Leu Leu Ala Ser Gln
                1145                1150                1155

 Thr Ser Arg Glu Ile Val Ala Gly Arg Phe Pro Ile Asn Lys Glu
                1160                1165                1170

 Leu Ala Leu Glu Met Ala Ala Leu Met Ala Gln Val Glu Tyr Gly
                1175                1180                1185

 Asp Leu Glu Lys Pro Ala Leu Pro Gly Pro Gly Gly Thr Ser Pro
                1190                1195                1200

 Ala Lys Ala Gln His Leu Leu Gln Gln Val Leu Asp Arg Phe His
                1205                1210                1215

 Pro Arg Arg Tyr Arg His Gly Ala Pro Ala Glu Gln Leu Arg His
                1220                1225                1230

 Leu Ala Asp Met Leu Thr Thr Lys Trp Ala Thr Leu Gln Gly Cys
                1235                1240                1245

 Ser Pro Pro Glu Cys Ile Arg Ile Tyr Leu Thr Val Ala Arg Lys
                1250                1255                1260

 Trp Pro Phe Phe Gly Ala Lys Leu Phe Ala Ala Gln Pro Ala Gln
                1265                1270                1275

 Leu Ser Ser Lys Glu Asn Ala Leu Val Trp Ile Ala Val Asn Glu
                1280                1285                1290

 Asp Gly Val Ser Ile Leu Asp His Asn Thr Met Gln Val His Ile
                1295                1300                1305

 Thr Tyr Pro Tyr Ser Ser Val Thr Thr Phe Gly Gly Cys Arg Asp
                1310                1315                1320

 Asp Phe Met Leu Val Ile Arg Ser Ile Pro Asp Lys Ser Ser Gly
                1325                1330                1335

 Lys Ser His Ile Glu Lys Leu Ile Phe Arg Met Ala Ala Pro Lys
                1340                1345                1350

 Ile Ala Glu Ala Thr Phe Ile Met Ala Ser Tyr Met Asn His Cys
                1355                1360                1365

 Thr Thr Thr Val Asn Pro Pro Thr Asn Pro Pro Gly Ala Cys Gln
                1370                1375                1380

 Leu Trp Glu Leu Asp Gly Arg Gln Phe Phe Ser Ser Val Ser Cys
                1385                1390                1395

 Ala Thr Lys Gly Pro Thr Leu Leu
                1400

<210> 4253
<211> 1566
<212> DNA
<213> Homo sapien

<400> 4253
 ggcacgaggg actcagcgaa gggtgggcgc cgccgaggcc tcctgccgct 50

 ggcgggtttc cgcggagtgc cgcccggctc cgctctgccg ccggcgcggc 100

 tcatgggcag agtcggccgg gcgggccggc attaaactga agaaaagatg 150

 tccctgtacg atgacctagg agtggagacc agtgactcaa aaacagaagg 200

 ctggtccaaa aacttcaaac ttctgcagtc tcagcttcag gtgaagaagg 250

 cagctctcac tcaggcaaag agccaaagga cgaaacaaag tacagtcctc 300

 gccccagtca ttgacctgaa gcgaggtggc tcctcagatg accggcaaat 350

 tgtggacact ccaccgcatg tagcagctgg gctgaaggat cctgttccca 400

 gtgggttttc tgcaggggaa gttctgattc ccttagctga cgaatatgac 450

 cctatgtttc ctaatgatta tgagaaagta gtgaagcgcc aaagagagga 500

 acgacagaga cagcgggagc tggaaagaca aaaggaaata gaagaaaggg 550

 aaaaaaggcg taaagacaga catgaagcaa gtgggtttgc aaggagacca 600

 gatccagatt ctgatgaaga tgaagattat gagcgagaga ggaggaaaag 650

 aagtatgggc ggagctgcca ttgccccacc cacttctctg gtagagaaag 700

 acaaagagtt accccgagat tttccttatg aagaggactc aagacctcga 750

 tcacagtctt ccaaagcagc cattcctccc ccagtgtacg aggaacaaga 800

 cagaccgaga tctccaaccg gacctagcaa ctccttcctc gctaacatgg 850

 ggggcacggt ggcgcacaag atcatgcaga agtacggctt ccgggagggc 900

 cagggtctgg ggaagcatga gcagggcctg agcactgcct tgtcagtgga 950

 gaagaccagc aagcgtggcg gcaagatcat cgtgggcgac gccacagaga 1000

 aagatgcatc caagaagtca gattcaaatc cgctgactga aatacttaag 1050

 tgtcctacta aagtggtctt actaaggaac atggttggtg cgggagaggt 1100

 ggatgaagac ttggaagttg aaaccaagga agaatgtgaa aaatatggca 1150

 aagttggaaa atgtgtgata tttgaaattc ctggtgcccc tgatgatgaa 1200

 gcagtacgga tatttttaga atttgagaga gttgaatcag caattaaagc 1250

 ggttgttgac ttgaatggga ggtattttgg tggacgggtg gtaaaagcat 1300

 gtttctacaa tttggacaaa ttcagggtct tggatttggc agaacaagtt 1350

 tgattttaag aactagagca cgagtcatct ccggtgatcc ttaaatgaac 1400

 tgcaggctga gaaaagaagg aaaaaggtca cagcctccat ggctgttgca 1450

 taccaagact cttggaagga cttctaagat atatgttgat tgatcccttt 1500

 tttattttgt ggttttttaa tatagtataa aaatcctttt aaaaaaacaa 1550

 aaaaaaaaaa aaaaaa 1566

<210> 4254
<211> 401
<212> PRT
<213> Homo sapien

<400> 4254
 Met Ser Leu Tyr Asp Asp Leu Gly Val Glu Thr Ser Asp Ser Lys
   1               5                  10                  15

 Thr Glu Gly Trp Ser Lys Asn Phe Lys Leu Leu Gln Ser Gln Leu
                  20                  25                  30

 Gln Val Lys Lys Ala Ala Leu Thr Gln Ala Lys Ser Gln Arg Thr
                  35                  40                  45

 Lys Gln Ser Thr Val Leu Ala Pro Val Ile Asp Leu Lys Arg Gly
                  50                  55                  60

 Gly Ser Ser Asp Asp Arg Gln Ile Val Asp Thr Pro Pro His Val
                  65                  70                  75

 Ala Ala Gly Leu Lys Asp Pro Val Pro Ser Gly Phe Ser Ala Gly
                  80                  85                  90

 Glu Val Leu Ile Pro Leu Ala Asp Glu Tyr Asp Pro Met Phe Pro
                  95                 100                 105

 Asn Asp Tyr Glu Lys Val Val Lys Arg Gln Arg Glu Glu Arg Gln
                 110                 115                 120

 Arg Gln Arg Glu Leu Glu Arg Gln Lys Glu Ile Glu Glu Arg Glu
                 125                 130                 135

 Lys Arg Arg Lys Asp Arg His Glu Ala Ser Gly Phe Ala Arg Arg
                 140                 145                 150

 Pro Asp Pro Asp Ser Asp Glu Asp Glu Asp Tyr Glu Arg Glu Arg
                 155                 160                 165

 Arg Lys Arg Ser Met Gly Gly Ala Ala Ile Ala Pro Pro Thr Ser
                 170                 175                 180

 Leu Val Glu Lys Asp Lys Glu Leu Pro Arg Asp Phe Pro Tyr Glu
                 185                 190                 195

 Glu Asp Ser Arg Pro Arg Ser Gln Ser Ser Lys Ala Ala Ile Pro
                 200                 205                 210

 Pro Pro Val Tyr Glu Glu Gln Asp Arg Pro Arg Ser Pro Thr Gly
                 215                 220                 225

 Pro Ser Asn Ser Phe Leu Ala Asn Met Gly Gly Thr Val Ala His
                 230                 235                 240

 Lys Ile Met Gln Lys Tyr Gly Phe Arg Glu Gly Gln Gly Leu Gly
                 245                 250                 255

 Lys His Glu Gln Gly Leu Ser Thr Ala Leu Ser Val Glu Lys Thr
                 260                 265                 270

 Ser Lys Arg Gly Gly Lys Ile Ile Val Gly Asp Ala Thr Glu Lys
                 275                 280                 285

 Asp Ala Ser Lys Lys Ser Asp Ser Asn Pro Leu Thr Glu Ile Leu
                 290                 295                 300

 Lys Cys Pro Thr Lys Val Val Leu Leu Arg Asn Met Val Gly Ala
                 305                 310                 315

 Gly Glu Val Asp Glu Asp Leu Glu Val Glu Thr Lys Glu Glu Cys
                 320                 325                 330

 Glu Lys Tyr Gly Lys Val Gly Lys Cys Val Ile Phe Glu Ile Pro
                 335                 340                 345

 Gly Ala Pro Asp Asp Glu Ala Val Arg Ile Phe Leu Glu Phe Glu
                 350                 355                 360

 Arg Val Glu Ser Ala Ile Lys Ala Val Val Asp Leu Asn Gly Arg
                 365                 370                 375

 Tyr Phe Gly Gly Arg Val Val Lys Ala Cys Phe Tyr Asn Leu Asp
                 380                 385                 390

 Lys Phe Arg Val Leu Asp Leu Ala Glu Gln Val
                 395                 400

<210> 4255
<211> 4481
<212> DNA
<213> Homo sapien

<400> 4255
 gtcatgtaag tggtatgtct ttgacagaaa catggttacg tggttcatga 50

 gtgtatattc actggaagat agtcaagact aaagacacat tagagcaaat 100

 tgaccccttt aacatgtgat tattgtccaa ttaaagacag ttgatttaag 150

 tagcatgagg tattatttta tttgtattcg atctgtgtta cctgggatcc 200

 agtatcaaat atatccacat tctttatcag caagcattca tggccattca 250

 gaagaaataa attaggtaac ttgataataa ggctaagtgg gagagtacct 300

 gttcaatagc tcatatatcg agtaccctgt catacaggaa caagttaaag 350

 gacacaattg aggttaggct agcttctaca aattgcaata tgcagttttt 400

 gaaagatttt ctaacaaaaa gccaataaat gtagccatct ccttgttgtt 450

 tgcaatggca gagcatccta gagttcctca gctaacctct cattatgtgt 500

 cttaaatgca aaagagccat taattatgcc agtatttgaa tcaaagaggt 550

 cattctctgt ctatagtgtt cccatccatg tgttccaaat gggagcatag 600

 catgaagtga tgcacatatt tcaccacggt atcatgtact tcatggccag 650

 tgttttatct cagcagggaa ctacgccaag ttgaaagatg gggttgggta 700

 aagtagatta ggtgaagtag aacataaaat tgaatagtac ccaattaaag 750

 ttcctcagta agaaaaaaaa atgtgttttt gtaggcaaaa agaacatttc 800

 taaagtctca aggaatagct tcctaaagtg ttgagtaaag aggctaaata 850

 agatgagact agtttaatat agagagaaaa atacctttat ggagtaaaag 900

 tgtacgtgat gatcatgggt tgtcagtgat ttgtgaactg agagcagcaa 950

 caacattatt ttttaaaaat cttaaatcct ctcttaatgg atggttaaca 1000

 aatgctcaaa gtccattact ctttttattg gctcttgcag gttttgtgtt 1050

 ttatcatcag tgcttttaga aatgcaggcc ttaacttact gaactgaact 1100

 ttctgaaaac gtaatgtagc agtatcaata tacttttggg cataaaaata 1150

 gtttcctagg taaggggtgt gagatattca aagaatacat gtggctaaca 1200

 agtgtaatga gaaagttcat gtgtcacatg aaaatgatca tgtttgtgtt 1250

 gctacagctt ttgtgggaaa tttagtttaa aggcagctct tggtgtacct 1300

 tagtatattt taatccacaa ttataccatt gatactgaga ggtgataccc 1350

 gatgatcttc tctataatat tcttagagta aaacaaaatc tcaaaagtat 1400

 taatagctct tctacccttg aaggtgactg gtcctgggac agttagaatc 1450

 tttcaggttt acctctgttc agcagatact tcagtaggat acatagcttt 1500

 tcttccagtg aaacaaagtt catatcatcc attgtttttc aagcacgtga 1550

 caccagcctc aaagtaaatg acatgaccag tggttgaaca gtctaatttt 1600

 caaatttaat atagagcata taacttctga tttgatagta tttattttaa 1650

 aaaattatgt tttcatcatt catttgaaaa tgaaaaagcc ccaaagtgag 1700

 aactttgggg gagggcctag aacatggata gatctcttag tggtctttcc 1750

 aaaagtacat gtacttgaaa tattttcatt atcatactat tctttgaaaa 1800

 aaaagatgct tactgtatac ttgttttcaa gcatcctcta aaatcaaagg 1850

 ttttgatcac aatatgcaga tttctcttga tagatactta aataggctat 1900

 ttctctcctc ttcttgggca atgccttgtt ttctcctctg aatatttgca 1950

 tttgaaagga ttgcttcctg ttctgctcat tgatcaaagg tagggccaat 2000

 taaggattct aaccctaacc cagcaccaca aagcccccct ggagcatctt 2050

 cccggctggc aggaccatgc catctctgtg gagaaggtgc tggggaggga 2100

 agtccttcca gtgccacatg gagtgaggcc ctgcccatgc tggggacttt 2150

 ggggaggaat ttggtattct ggtggccttg ctcagctctc attgagatct 2200

 tttcctatca gaatgttagt gaatatactt cgcagctctt tgttcagcaa 2250

 taaggaatat tctttcaatt cctgctcttc aagccaattt actacaccca 2300

 gttgtctttc cagaagttca tcccagcggt aatatgttgg tgtttgttct 2350

 tctttggatt tcacatctgt tttctggtag aagtgagcac tgttcacttg 2400

 tgcagtcgtc ttattttcct tcttcctaga tgactcagct ctttgtaaat 2450

 gttgtgctca acttctaggg gccagttcta gactttggag atgcagtgtc 2500

 tcccaggtgt gcacggacac ctggtccgtg gaaacaggtg tgatgggcac 2550

 aggctgctgc ccttctgtct ggtcggggga ttcctcttct tcaagctgct 2600

 cagctaaccc agaagagggg agagagtact ccggtggttc ccagagcccc 2650

 tcccgttgtg ccgcttcgac ctgacacctg ctcgatgctg acttaggctt 2700

 cctgccacca agcaggaaac tagaaagaga acatttcagt gtaaggtctg 2750

 ttcccgacag catggattag cttccgtgtt ctgaagttgt tcttttcatg 2800

 gtgtctgaca ccgagggcgt tgttcgtcca tcaggcggga ttggatggag 2850

 tcttggtgtt ttgccttctc agggaccaaa aatgtatcat tgactcctta 2900

 acagtgacct tcctcccaag gacatatccg tgttcatttt tcataggttt 2950

 tactcatatt cataggtaga ttctgttaat gtgagttgga aagaaaagac 3000

 caatttgtac accagtcaca ccacaagaca gtttatcata taaaatacct 3050

 caattttttg tattcctcat ttccacctca caattgtact ggtgatgaat 3100

 tttaagggtc tgtcctttag cttataggtg atgtttcaca tctggccaga 3150

 ttcttatacc tccattgtat acttgaaaag gttcagaatt acaggaacag 3200

 cagtgagaat ttggcccact accacgactc atttgtttca ttcacattcc 3250

 tcacgtgcaa caacataatt atattttaag aaaatgtaac tttgttacat 3300

 caaaatatgt tgtctagtaa aaagttgata ttcagtagaa caaggatcat 3350

 gtaaataaac atctatttca catgtaccca aaagcattta aaaagcagaa 3400

 tccagggccc agagcatgag ccagggagga ggatgttttt cttcttttct 3450

 ctatttttcc ctaaattgtg caaacatagg tgagtctctt aacctttctg 3500

 tgcctcagtt tttctacctc taaaggggtg ggatggttct tcaaattgtt 3550

 tctaaaacac cggcactttc agcagtgttc tggtggcctg agatgagagc 3600

 accgtgttca gaagtgcctg ggagtggcac agtggaaact ccgcttgcac 3650

 ggaccatgga gtctgctcag gaccatgctg taggacacac agcctcatgc 3700

 gctgagaaag caaaggaagt gctgggtgta aagtttgcat gattccatga 3750

 agctttagtt ttcctttttt tgttttaaaa gaaagggttt tatatgttct 3800

 attgtaaaat atggaaatta aacagggact tcagaaagcc gcacagaaag 3850

 atcaccttcc gatggtgtga tgtgctcctg acattcggcc gaggtctgta 3900

 ttctgaaaaa gatttaatgg cctgtgaaac acgtggattc tgttgcactg 3950

 gatttgtaat aaatgacgct gaacttcctg cttccaagca gctcaaccct 4000

 gatgctgaac tgacaccagg cgaatgtcag ggctcccaaa ccactagtgc 4050

 caaagggtca tgttgaaaag ttcagaatat ttatttgtca gaatataata 4100

 attgcccccc accttagtat ttttgcactt tacagaaatt tagatactgt 4150

 ttttcagtgg cttgagcgtt ttgccttttc aaaggataac tattattttc 4200

 ttgaaaatgg aatataatca tgagaggaag aagatgtaaa aaatgtcaaa 4250

 tgttgattgg ttgtgtaaaa gttttgtcat agacatgtat tggggagctt 4300

 ccaattagca tacatagaca catgtgtcag tggccaagac ctgcttatat 4350

 tttgctttat agatgtagtc atagcatgtt gttattgcct catgtaaata 4400

 aaaaggctat taagttttcc agtaatattt attaatctgt atgtgtttta 4450

 aaataaaata acttatttct agctgaaaaa a 4481

<210> 4256
<211> 26
<212> PRT
<213> Homo sapien

<400> 4256
 Ser Cys Lys Trp Tyr Val Phe Asp Arg Asn Met Val Thr Trp Phe
   1               5                  10                  15

 Met Ser Val Tyr Ser Leu Glu Asp Ser Gln Asp
                  20                  25

<210> 4257
<211> 6414
<212> DNA
<213> Homo sapien

<400> 4257
 ctcggaattc gttatcgagg ttggcggccg ggctgccagg agcagttccg 50

 ccgggtttca ctgtccgtga cttccttcgg ggcacctcag gcagcaaacc 100

 aagatggagt atgagtggaa acctgacgag caagggcttc agcaaatcct 150

 gcagctgttg aaggagtccc agtccccaga caccaccatc cagagaaccg 200

 tgcaacaaaa actggaacaa cttaatcagt atccagactt taacaactac 250

 ttgatttttg ttcttacaaa attaaaatct gaagatgaac ccacaagatc 300

 attgagtggt cttatcttga agaataatgt gaaagcacac tttcagaact 350

 tcccaaatgg tgtaacagac tttattaaaa gtgaatgttt aaataatatt 400

 ggtgactcct ctcctctgat tagagccact gttggtattt tgatcacaac 450

 tatagcctcc aagggagaat tgcagaattg gcctgacctc ttaccaaaac 500

 tctgtagcct gttggattct gaagattata atacctgtga gggagcattt 550

 ggtgcccttc agaagatttg tgaagattct gctgagattt tagacagtga 600

 tgttttagat cgtcctctca acatcatgat tcccaaattt ttacagttct 650

 tcaagcatag tagtccaaaa ataaggtctc acgctgttgc atgtgtcaat 700

 cagtttatca tcagtaggac tcaagctcta atgttgcaca ttgattcttt 750

 tattgagaat ctctttgcat tagctggtga tgaagaacca gaggtacgga 800

 aaaatgtgtg ccgagcactt gtgatgttgc tcgaagttcg aatggatcgc 850

 ctgcttcctc acatgcataa tatagttgag tacatgctac agaggactca 900

 agatcaagat gaaaatgtgg ctttagaagc ctgtgaattt tggctaactt 950

 tagctgaaca gccaatatgc aaagatgtac tcgtaaggca tcttcctaag 1000

 ttgattcctg tgttagtgaa tggcatgaag tactcagaca tagatattat 1050

 cctacttaag ggtgatgttg aagaagacga aacgattcct gatagtgaac 1100

 aggatatacg gccacgtttt caccgatcga ggacggtggc tcagcagcat 1150

 gatgaagatg gaattgaaga ggaagatgat gatgatgatg aaattgatga 1200

 tgatgataca atttctgact ggaatctaag aaaatgttct gctgctgccc 1250

 tggatgttct tgcaaatgtg tatcgtgatg aactgctgcc acatattttg 1300

 ccccttttga aagaattact ttttcatcat gaatgggttg ttaaagaatc 1350

 aggcattttg gttttaggag caattgctga aggttgcatg cagggcatga 1400

 ttccatactt gcctgagctt attcctcacc ttattcagtg cctctctgat 1450

 aaaaaggctc ttgtgcgttc cataacatgc tggactctta gccgctatgc 1500

 acactgggtg gtcagccagc cgccagacac gtacctgaag ccattaatga 1550

 cagaattgct aaagcgcatc ctggatagca acaagagagt acaagaagct 1600

 gcctgcagtg cctttgctac cctagaagag gaggcttgta cagaacttgt 1650

 tccttacctt gcttatatac ttgataccct ggtctttgca tttagtaaat 1700

 accagcataa gaacctgctc attctttacg atgccatagg aacattagca 1750

 gattcagtag gacatcattt aaacaaacca gaatatattc agatgctaat 1800

 gcctccactg atccagaaat ggaacatgtt aaaggatgaa gataaagatc 1850

 tcttcccttt acttgagtgc ctatcttcag ttgccacagc actgcagtct 1900

 ggattccttc cgtactgtga acctgtgtat cagcgttgtg taaacctagt 1950

 acagaagact cttgcacaag ccatgctaaa caatgctcaa ccagatcaat 2000

 atgaagctcc agataaagat tttatgatag tggctcttga tttactgagt 2050

 ggcctggctg aaggacttgg aggcaacatt gaacagctgg tagcccgaag 2100

 taacatcctg acactaatgt atcagtgcat gcaggataaa atgccagaag 2150

 ttcgacagag ttcttttgcc ctgttaggtg acctcacaaa agcttgcttt 2200

 cagcatgtta agccttgtat agctgatttc atgccaatat tgggaaccaa 2250

 cctaaatcca gaattcattt cagtctgcaa caatgccaca tgggcaattg 2300

 gagaaatctc cattcaaatg ggtatagaga tgcagcctta tattcctatg 2350

 gtgttgcacc agcttgtaga aatcattaac agacccaaca caccaaagac 2400

 gttgttagag aatacagcaa taacaattgg tcgtcttggt tacgtttgtc 2450

 ctcaagaggt ggcccccatg ctacagcagt ttataagacc ctggtgcacc 2500

 tctctgagaa acataagaga caatgaggaa aaggattcag cattccgtgg 2550

 aatttgtacc atgatcagtg tgaatcccag tggcgtaatc caagatttta 2600

 tatttttttg tgatgccgtt gcatcatgga ttaacccaaa agatgatctc 2650

 agagacatgt tctgtaagat ccttcatgga tttaaaaatc aagttggcga 2700

 tgaaaattgg aggcgtttct ctgaccagtt tcctcttccc ttaaaagagc 2750

 gtcttgcagc tttttatggt gtttaatcta atacacttaa gctgcagtcc 2800

 caaaattagg ggtccttcag tcttggagac tataagggag cctctgcacc 2850

 cagggaaaat gttacccttt acagggggga agggtaaacc agtagggaat 2900

 acagtacaat cccaacccta ctgggagggg cgggagggag gtgttgccgt 2950

 cactgtatta agtcgatgtt gggaaacgtt ttaacatctg gagcctttgt 3000

 gggtggaaat atgtctccag ttacaactcc gcagtggatg tgaagaagca 3050

 aaaaaaaaaa aatctattca gtctactcac aaaacagtac attgtggaat 3100

 attatgggga attgtaccaa aacaagaacc atataaatga tgcctaggga 3150

 caagaaagag gaacaattct atagcgcaca ataaaggaaa cctaagaatg 3200

 ggagttacaa atagtaaaga agcttttttt ttttttaatt taaagttttt 3250

 ttatgtaagt tttcccacat gatggggcct tgttttgcat gttgatgaag 3300

 aactacacaa agaaaactaa tatagttaaa agtcagcttg ccttcccgta 3350

 gtagaagcag gttcttggaa gttacaattt aaggtacccc aaaaaagttg 3400

 gaaataaaac aaaacaaaca taaacaatga agcaccctgt gaaatgccaa 3450

 atgagtcact ccttttacct tttttggggt gggcagggag ggaggaataa 3500

 atggggttgg gcatatcaaa ctaaagatga catcttaatt ttgcattgaa 3550

 cattaatgta gcggatataa tttgatgatt atacttcatt agatttaatt 3600

 tctaggccaa gatgttactt tttaaagtgc agtttaaggt tcaggcatgc 3650

 attctggctc atagtggttg aaagtaattt aaattagtgg gaaagtagca 3700

 tgcttgcatc acatagagtg agattggtat tcatttacct atgttgcgcc 3750

 agtttgtgtt gcagtttacc aattcaatat agccctgcat ttaaagttcc 3800

 tttttaagat ttgtggattt tatttttatt aagaacatag atatataaag 3850

 tactgtagtt tacaggtagg ccttgaaata tcttttttag gatctgttag 3900

 gaataagatt gatattgtat tgtgtgtaac ctgcacaatg tggaaagctg 3950

 atatacctgt gcaaaatctt tgcctctgtg ctgtcagtgt gatgtgcttt 4000

 ctgcatggtt atatactact agtgatttta tcaaaacttc taaaatttaa 4050

 attacgtggt aaaagatctg taaaaggctg cataaatgtt agttggcaca 4100

 taaagacaat tgtagaagtt gaaaaatgat tgctatattt caatgtttat 4150

 tcccactcaa catactgcct tctaagcttc cctttttttg ttcaaagcat 4200

 gatcttaaag atatgtttaa gttaatggat gtaatgcagg gttcctacac 4250

 tgtattttgg cgcatgttgg tggccctctg tgccctagat atatgcacac 4300

 agggtgcaag ttaaaagcta cagagtgaaa gttggtttgg atcctcttca 4350

 tttcatttgt ttagcttttc tgttattttt ctctacttac atgtattcct 4400

 gtgaataaat ccttgttaag ttaacccttt acttttcctt ccatgtgtat 4450

 tttcttatat actgtgaatg tgaaaaccta actggtacac ttgatcttgt 4500

 gttcatatga aagtgcaagt ctttattaat ttggattgcc tgaacagtgt 4550

 atcccatgat gatgaaggaa aatggagaga tttttctttt taactctgct 4600

 ggtcagagat gaagccacgc ctttccattt ttcaatgctg catatttaat 4650

 ctgcaacaaa aatgttaagc cataacagcc tttttatatt ttagtttgtc 4700

 acctttgcat tgcagaataa atactgaata accattttta taagcagttg 4750

 ctcctctttg catggttcta ttctctaaaa gtgttgaatg atacagccat 4800

 tgcactgaag tttgagctgt gtgcgtgtga atttatactg tttcaaaaat 4850

 ttcaaatgca tggtagcatg tagaaaggtt ttgttactat gtgtgtgtgt 4900

 gtgtcatgta aagtagagtc tgttttttaa cgttctttca cctttcctct 4950

 actttggctt tgcaaatttc agtctgtaga gcctgaaatt aaattatttt 5000

 atagtgcctg atatttttaa tattataagt tggattcaaa gggtatacag 5050

 cattttgttt tctagtacca ttgcttcact gggagctcaa aatttgcctc 5100

 cctgttagtc tttaataact gagtagagta gctgttttat tcttagatta 5150

 tagtgatatt ctgtagtgct tcaaatactt agaattctaa tatgagagat 5200

 agtttaatat tctggaatag agagtatttt aaattgaaat gaccaaattc 5250

 gatttaaaac aaacacataa caatcttcag taaagttatt tgaacctgtg 5300

 gttgacaatt ctgtattgac taaaggcaat attgtcacct gtctcattaa 5350

 aaattagttt ccagttaggc agatgaataa cactattaaa aatgcaccca 5400

 gttttgtagt cacttgactt ttttttttta tttaaatgaa atttaatttg 5450

 aaaatagaaa ataaaattag gtaaatatga ctggcaacct gaatttgagt 5500

 tgggattctt tgtgtatttt tcccccttga ggttatggtt tcttcctaat 5550

 ttatatttca gatacatagt gtagaacagg aatttgcaga agccatttaa 5600

 gttatctttt gaggtaagct ctgatttagc atttattctg ataaaatcta 5650

 atacatcatg ggatatatat aaagcaactt aattctggtg gtgtagtctt 5700

 aatagtttgg aatgttgact gaatgtctat aaaaattgtg agtttgtctt 5750

 ttgtttacat tccagtgttt ctgcctctgg gcatgcttaa agcacggctt 5800

 acttcatctg ctccttacac actaaaagtg ctgttagtgt gctcaactac 5850

 agaaatagcc gctgctaagt gatgtagatt ttctacttga atatttttat 5900

 gttgtaggaa cctcaggagg tcagtgttta ctgttttata tatgccttct 5950

 ttttcctgtt tgagcttctc tctttgaagg attctaacag aacaaagctg 6000

 ctgatcaacc taagttggaa acagaaagtg taattaatat aacttaaatg 6050

 catgtttggc agttcacttg ttttgagaca cctgaagagg catttctccc 6100

 agccccttca gaacaacctg gttacagagt tactacacct ggagacagag 6150

 gccgatttta gtatgttttc agagactagt acaactggga gtgctctctg 6200

 gagattatgt tgctgaagac tttctggctg ttttcctttt gaaacacact 6250

 agaaagctct tctggagata cttatgggag aaggactcca tccccaccac 6300

 ccacccccaa cctagaccta tagccagcca gccactgtcc tcctgcgtct 6350

 tcactacagc ccaactcaag aggaaacatg agatagtaaa gaccacacta 6400

 atagccaaga atct 6414

<210> 4258
<211> 890
<212> PRT
<213> Homo sapien

<400> 4258
 Met Glu Tyr Glu Trp Lys Pro Asp Glu Gln Gly Leu Gln Gln Ile
   1               5                  10                  15

 Leu Gln Leu Leu Lys Glu Ser Gln Ser Pro Asp Thr Thr Ile Gln
                  20                  25                  30

 Arg Thr Val Gln Gln Lys Leu Glu Gln Leu Asn Gln Tyr Pro Asp
                  35                  40                  45

 Phe Asn Asn Tyr Leu Ile Phe Val Leu Thr Lys Leu Lys Ser Glu
                  50                  55                  60

 Asp Glu Pro Thr Arg Ser Leu Ser Gly Leu Ile Leu Lys Asn Asn
                  65                  70                  75

 Val Lys Ala His Phe Gln Asn Phe Pro Asn Gly Val Thr Asp Phe
                  80                  85                  90

 Ile Lys Ser Glu Cys Leu Asn Asn Ile Gly Asp Ser Ser Pro Leu
                  95                 100                 105

 Ile Arg Ala Thr Val Gly Ile Leu Ile Thr Thr Ile Ala Ser Lys
                 110                 115                 120

 Gly Glu Leu Gln Asn Trp Pro Asp Leu Leu Pro Lys Leu Cys Ser
                 125                 130                 135

 Leu Leu Asp Ser Glu Asp Tyr Asn Thr Cys Glu Gly Ala Phe Gly
                 140                 145                 150

 Ala Leu Gln Lys Ile Cys Glu Asp Ser Ala Glu Ile Leu Asp Ser
                 155                 160                 165

 Asp Val Leu Asp Arg Pro Leu Asn Ile Met Ile Pro Lys Phe Leu
                 170                 175                 180

 Gln Phe Phe Lys His Ser Ser Pro Lys Ile Arg Ser His Ala Val
                 185                 190                 195

 Ala Cys Val Asn Gln Phe Ile Ile Ser Arg Thr Gln Ala Leu Met
                 200                 205                 210

 Leu His Ile Asp Ser Phe Ile Glu Asn Leu Phe Ala Leu Ala Gly
                 215                 220                 225

 Asp Glu Glu Pro Glu Val Arg Lys Asn Val Cys Arg Ala Leu Val
                 230                 235                 240

 Met Leu Leu Glu Val Arg Met Asp Arg Leu Leu Pro His Met His
                 245                 250                 255

 Asn Ile Val Glu Tyr Met Leu Gln Arg Thr Gln Asp Gln Asp Glu
                 260                 265                 270

 Asn Val Ala Leu Glu Ala Cys Glu Phe Trp Leu Thr Leu Ala Glu
                 275                 280                 285

 Gln Pro Ile Cys Lys Asp Val Leu Val Arg His Leu Pro Lys Leu
                 290                 295                 300

 Ile Pro Val Leu Val Asn Gly Met Lys Tyr Ser Asp Ile Asp Ile
                 305                 310                 315

 Ile Leu Leu Lys Gly Asp Val Glu Glu Asp Glu Thr Ile Pro Asp
                 320                 325                 330

 Ser Glu Gln Asp Ile Arg Pro Arg Phe His Arg Ser Arg Thr Val
                 335                 340                 345

 Ala Gln Gln His Asp Glu Asp Gly Ile Glu Glu Glu Asp Asp Asp
                 350                 355                 360

 Asp Asp Glu Ile Asp Asp Asp Asp Thr Ile Ser Asp Trp Asn Leu
                 365                 370                 375

 Arg Lys Cys Ser Ala Ala Ala Leu Asp Val Leu Ala Asn Val Tyr
                 380                 385                 390

 Arg Asp Glu Leu Leu Pro His Ile Leu Pro Leu Leu Lys Glu Leu
                 395                 400                 405

 Leu Phe His His Glu Trp Val Val Lys Glu Ser Gly Ile Leu Val
                 410                 415                 420

 Leu Gly Ala Ile Ala Glu Gly Cys Met Gln Gly Met Ile Pro Tyr
                 425                 430                 435

 Leu Pro Glu Leu Ile Pro His Leu Ile Gln Cys Leu Ser Asp Lys
                 440                 445                 450

 Lys Ala Leu Val Arg Ser Ile Thr Cys Trp Thr Leu Ser Arg Tyr
                 455                 460                 465

 Ala His Trp Val Val Ser Gln Pro Pro Asp Thr Tyr Leu Lys Pro
                 470                 475                 480

 Leu Met Thr Glu Leu Leu Lys Arg Ile Leu Asp Ser Asn Lys Arg
                 485                 490                 495

 Val Gln Glu Ala Ala Cys Ser Ala Phe Ala Thr Leu Glu Glu Glu
                 500                 505                 510

 Ala Cys Thr Glu Leu Val Pro Tyr Leu Ala Tyr Ile Leu Asp Thr
                 515                 520                 525

 Leu Val Phe Ala Phe Ser Lys Tyr Gln His Lys Asn Leu Leu Ile
                 530                 535                 540

 Leu Tyr Asp Ala Ile Gly Thr Leu Ala Asp Ser Val Gly His His
                 545                 550                 555

 Leu Asn Lys Pro Glu Tyr Ile Gln Met Leu Met Pro Pro Leu Ile
                 560                 565                 570

 Gln Lys Trp Asn Met Leu Lys Asp Glu Asp Lys Asp Leu Phe Pro
                 575                 580                 585

 Leu Leu Glu Cys Leu Ser Ser Val Ala Thr Ala Leu Gln Ser Gly
                 590                 595                 600

 Phe Leu Pro Tyr Cys Glu Pro Val Tyr Gln Arg Cys Val Asn Leu
                 605                 610                 615

 Val Gln Lys Thr Leu Ala Gln Ala Met Leu Asn Asn Ala Gln Pro
                 620                 625                 630

 Asp Gln Tyr Glu Ala Pro Asp Lys Asp Phe Met Ile Val Ala Leu
                 635                 640                 645

 Asp Leu Leu Ser Gly Leu Ala Glu Gly Leu Gly Gly Asn Ile Glu
                 650                 655                 660

 Gln Leu Val Ala Arg Ser Asn Ile Leu Thr Leu Met Tyr Gln Cys
                 665                 670                 675

 Met Gln Asp Lys Met Pro Glu Val Arg Gln Ser Ser Phe Ala Leu
                 680                 685                 690

 Leu Gly Asp Leu Thr Lys Ala Cys Phe Gln His Val Lys Pro Cys
                 695                 700                 705

 Ile Ala Asp Phe Met Pro Ile Leu Gly Thr Asn Leu Asn Pro Glu
                 710                 715                 720

 Phe Ile Ser Val Cys Asn Asn Ala Thr Trp Ala Ile Gly Glu Ile
                 725                 730                 735

 Ser Ile Gln Met Gly Ile Glu Met Gln Pro Tyr Ile Pro Met Val
                 740                 745                 750

 Leu His Gln Leu Val Glu Ile Ile Asn Arg Pro Asn Thr Pro Lys
                 755                 760                 765

 Thr Leu Leu Glu Asn Thr Ala Ile Thr Ile Gly Arg Leu Gly Tyr
                 770                 775                 780

 Val Cys Pro Gln Glu Val Ala Pro Met Leu Gln Gln Phe Ile Arg
                 785                 790                 795

 Pro Trp Cys Thr Ser Leu Arg Asn Ile Arg Asp Asn Glu Glu Lys
                 800                 805                 810

 Asp Ser Ala Phe Arg Gly Ile Cys Thr Met Ile Ser Val Asn Pro
                 815                 820                 825

 Ser Gly Val Ile Gln Asp Phe Ile Phe Phe Cys Asp Ala Val Ala
                 830                 835                 840

 Ser Trp Ile Asn Pro Lys Asp Asp Leu Arg Asp Met Phe Cys Lys
                 845                 850                 855

 Ile Leu His Gly Phe Lys Asn Gln Val Gly Asp Glu Asn Trp Arg
                 860                 865                 870

 Arg Phe Ser Asp Gln Phe Pro Leu Pro Leu Lys Glu Arg Leu Ala
                 875                 880                 885

 Ala Phe Tyr Gly Val
                 890

<210> 4259
<211> 2073
<212> DNA
<213> Homo sapien

<400> 4259
 ctcgtccgct cgcgctgccc accgcggctc cagcagctcc aggcgcggtt 50

 ccccggcccg cgccgctccc ggccccccgg ctcgggcgcc tcccgccgca 100

 gcgcaggctc ccccgccggc cgggctcctg cgcggcgcgg ctcggctcat 150

 gcccccgggc gcggggcaca caggccggcc ggcagccgct gggaaatagg 200

 cccccggggg cggtggcggc ggcggggcca tggcgcggag accccgggcg 250

 ccggccgcct ccggggagga gttctccttc gtcagcccgc tggtgaaata 300

 cctgctcttc ttcttcaaca tgctcttctg ggtgatttcc atggtgatgg 350

 tggctgtggg tgtctacgct cggctaatga agcatgcaga agcagcccta 400

 gcctgcctgg cagtggaccc tgccatcctg ctgatcgtgg tgggtgtcct 450

 catgttcctg ctcaccttct gtggctgcat tgggtccctc cgcgagaaca 500

 tctgcctcct gcagacgttc tccctctgcc tcaccgctgt gttcctgctg 550

 cagctggccg ctgggatcct gggcttcgtc ttctcagaca aggctcgagg 600

 gaaagtgagt gagatcatca acaatgccat tgtgcactac cgagatgact 650

 tggatctgca gaacctcatt gattttggcc agaaaaagtt tagctgctgt 700

 ggagggattt cctacaagga ctggtctcag aacatgtatt tcaactgctc 750

 agaagacaac cccagtcgag agcgctgctc tgtgccttac tcctgttgct 800

 tgcctactcc tgaccaggca gtgatcaaca ctatgtgtgg ccaaggtatg 850

 caggcctttg actacttgga agctagcaaa gtcatctaca ccaatggctg 900

 tattgacaag ttggtcaact ggatacacag caacctattc ttacttggtg 950

 gtgtggctct aggcctggcc atcccccagc tggtgggaat tctgctgtcc 1000

 cagatcctag tgaatcagat caaagatcag atcaagctac agctctacaa 1050

 ccagcagcac cgggctgacc catggtactg agaatccatc ctgcacctcc 1100

 tcaccatgga aactggcaag cctcataaac gaacagcagt gggtgctgaa 1150

 agcagcacca aatggagatt tggattccag ccccccagtg acagcccagt 1200

 gggaagaagc aaactccaga tgggcagaag gcagggtgca caggtggctc 1250

 cagtctcagg aggatgcgcc tcctctcccc catcccagtc ctcagcattg 1300

 tgccagagtg atacccttaa gtgtttgggt ttatgttttc agttttgttt 1350

 gggaaacagc agttgcacag agagttgggg gtactgctgc tgccttttca 1400

 ccgaggcact gccaccacca gctctagcag ggatgctcct gagcttggcg 1450

 gacatactta gatcctaacg tgccagtgag acctggctgt ggagagtagc 1500

 actggcagcc ctgcctggac tccacttggc atgataccag ctccagaagg 1550

 gaagggagtg gagcaggcag tgaggagaga gcctgggggt cggctgggga 1600

 cagccgtatg tgctaggtag gagtggaggg agatatgttt accaaatgcc 1650

 tgtcctgcca tcctcccagg tagtcagagt gagctacatc ctgccccgcc 1700

 ttcatttcca tggaaacatg gcagctagga cacggggtac aacagcagcc 1750

 aaattcttcc ccacctccct tacttcgaaa aaaagtttgg aaccctggtc 1800

 cctatactct gcagtcagaa gtgggactga gccatacatg cccttgaatt 1850

 cctccctgtc tggccctccc tctccagcaa gcagggtttt ctttaacttg 1900

 gcagtgtgca gaggagaagt ggtaacaccc ccaccccatt cccctgcatc 1950

 ggagctcagt attcctacag ggtaagaggt aggaatcttg ctgggacgag 2000

 gggagccaga agtggcaata aaagcgtgtt gacctggaaa aaaaaaaaaa 2050

 aaaaaaaaaa aaaaaaaaaa aaa 2073

<210> 4260
<211> 283
<212> PRT
<213> Homo sapien

<400> 4260
 Met Ala Arg Arg Pro Arg Ala Pro Ala Ala Ser Gly Glu Glu Phe
   1               5                  10                  15

 Ser Phe Val Ser Pro Leu Val Lys Tyr Leu Leu Phe Phe Phe Asn
                  20                  25                  30

 Met Leu Phe Trp Val Ile Ser Met Val Met Val Ala Val Gly Val
                  35                  40                  45

 Tyr Ala Arg Leu Met Lys His Ala Glu Ala Ala Leu Ala Cys Leu
                  50                  55                  60

 Ala Val Asp Pro Ala Ile Leu Leu Ile Val Val Gly Val Leu Met
                  65                  70                  75

 Phe Leu Leu Thr Phe Cys Gly Cys Ile Gly Ser Leu Arg Glu Asn
                  80                  85                  90

 Ile Cys Leu Leu Gln Thr Phe Ser Leu Cys Leu Thr Ala Val Phe
                  95                 100                 105

 Leu Leu Gln Leu Ala Ala Gly Ile Leu Gly Phe Val Phe Ser Asp
                 110                 115                 120

 Lys Ala Arg Gly Lys Val Ser Glu Ile Ile Asn Asn Ala Ile Val
                 125                 130                 135

 His Tyr Arg Asp Asp Leu Asp Leu Gln Asn Leu Ile Asp Phe Gly
                 140                 145                 150

 Gln Lys Lys Phe Ser Cys Cys Gly Gly Ile Ser Tyr Lys Asp Trp
                 155                 160                 165

 Ser Gln Asn Met Tyr Phe Asn Cys Ser Glu Asp Asn Pro Ser Arg
                 170                 175                 180

 Glu Arg Cys Ser Val Pro Tyr Ser Cys Cys Leu Pro Thr Pro Asp
                 185                 190                 195

 Gln Ala Val Ile Asn Thr Met Cys Gly Gln Gly Met Gln Ala Phe
                 200                 205                 210

 Asp Tyr Leu Glu Ala Ser Lys Val Ile Tyr Thr Asn Gly Cys Ile
                 215                 220                 225

 Asp Lys Leu Val Asn Trp Ile His Ser Asn Leu Phe Leu Leu Gly
                 230                 235                 240

 Gly Val Ala Leu Gly Leu Ala Ile Pro Gln Leu Val Gly Ile Leu
                 245                 250                 255

 Leu Ser Gln Ile Leu Val Asn Gln Ile Lys Asp Gln Ile Lys Leu
                 260                 265                 270

 Gln Leu Tyr Asn Gln Gln His Arg Ala Asp Pro Trp Tyr
                 275                 280

<210> 4261
<211> 1366
<212> DNA
<213> Homo sapien

<400> 4261
 gcgtctcgca gcagccgccc ggaccgggca tggtgttggg cgccgggccc 50

 gcctcgcctg tctcggggag cccagggtaa aggcagcagt aatgctaacg 100

 ctagcaagta aactgaagcg tgacgatggt ctcaaagggt cccggacggc 150

 agccacagcg tccgactcga ctcggagggt ttctgtgaga gacaaattgc 200

 ttgttaaaga ggttgcagaa cttgaagcta atttaccttg tacatgtaaa 250

 gtgcattttc ctgatccaaa caagcttcat tgttttcagc taacagtaac 300

 cccagatgag ggttactacc agggtggaaa atttcagttt gaaactgaag 350

 ttcccgatgc gtacaacatg gtgcctccca aagtgaaatg cctgaccaag 400

 atctggcacc ccaacatcac agagacaggg gaaatatgtc tgagtttatt 450

 gagagaacat tcaattgatg gcactggctg ggctcccaca agaacattaa 500

 aggatgtcgt ttggggatta aactctttgt ttactgatct tttgaatttt 550

 gatgatccac tgaatattga agctgcagaa catcatttgc gggacaagga 600

 ggacttccgg aataaagtgg atgactacat caaacgttat gccagatgat 650

 aaaaggggac gattgcaggc ccatggactg tgttacagtt tgtctctaac 700

 atgaaacagc aagaggtagc cccctctccc gtcctcatgc tccctctcag 750

 tcccctggat tgccccagtc ctgtgaccat gttgccctga agaagaccat 800

 cttcatgact gctcattgta gatggagaat tcaacataaa tacagcaaga 850

 aaatgtgttt gggcttctga agagttgtct gcttacctta acatgtttac 900

 ttttttgaac ttgtactgta taggctgttg gtgaaattct taagaagttg 950

 taatgaactc aaaattgagg ccagagcttg ctttcccttt tcccaaacaa 1000

 aattggtttt ctgcacaagc gatgctaatg atgtgttcag tgtaactcgc 1050

 agattggcaa taagataccc gctacaaact gtgattggat gcaaaatctc 1100

 ttagcttctt tcacgaatgt tggccctgcc tagatgttgt gaagcctccc 1150

 agaatgcata gagtcattca ctgtagatct cttattgaaa tgcgtatttt 1200

 atttaatgta agtatatttt ggaacagatt tgtaatttgt acaattcaat 1250

 gctttaatta ttttttctat tctcatttag tttgtatttt cattgtatag 1300

 agcagacaga aagatgttgg gtcaagcaac tattgaagag aaatacaaag 1350

 aaaaaaaaaa aaaaaa 1366

<210> 4262
<211> 185
<212> PRT
<213> Homo sapien

<400> 4262
 Met Leu Thr Leu Ala Ser Lys Leu Lys Arg Asp Asp Gly Leu Lys
   1               5                  10                  15

 Gly Ser Arg Thr Ala Ala Thr Ala Ser Asp Ser Thr Arg Arg Val
                  20                  25                  30

 Ser Val Arg Asp Lys Leu Leu Val Lys Glu Val Ala Glu Leu Glu
                  35                  40                  45

 Ala Asn Leu Pro Cys Thr Cys Lys Val His Phe Pro Asp Pro Asn
                  50                  55                  60

 Lys Leu His Cys Phe Gln Leu Thr Val Thr Pro Asp Glu Gly Tyr
                  65                  70                  75

 Tyr Gln Gly Gly Lys Phe Gln Phe Glu Thr Glu Val Pro Asp Ala
                  80                  85                  90

 Tyr Asn Met Val Pro Pro Lys Val Lys Cys Leu Thr Lys Ile Trp
                  95                 100                 105

 His Pro Asn Ile Thr Glu Thr Gly Glu Ile Cys Leu Ser Leu Leu
                 110                 115                 120

 Arg Glu His Ser Ile Asp Gly Thr Gly Trp Ala Pro Thr Arg Thr
                 125                 130                 135

 Leu Lys Asp Val Val Trp Gly Leu Asn Ser Leu Phe Thr Asp Leu
                 140                 145                 150

 Leu Asn Phe Asp Asp Pro Leu Asn Ile Glu Ala Ala Glu His His
                 155                 160                 165

 Leu Arg Asp Lys Glu Asp Phe Arg Asn Lys Val Asp Asp Tyr Ile
                 170                 175                 180

 Lys Arg Tyr Ala Arg
                 185

<210> 4263
<211> 2338
<212> DNA
<213> Homo sapien

<400> 4263
 ctgaactcgg gtgttatctg tcctgagaga acattcatga ttctaaaata 50

 taaaattcga gttgcaaatg tcatgtgcct ggaagctgag ggaagtttta 100

 gacacctgcc cagtttccct ctcctgccca ctgtggtaca gcacgacatt 150

 ctagtttctc ctgatgcttc gtcaaagaca tttagtgcag ttatgtcctg 200

 ttccttggtt gggccacaat ggagagaata gtacttgaga aggatttctc 250

 tgtaagaata ccatggcaga gagacccctc tgccccctgc tttgcattgc 300

 taacagttat tagcatttta tatttcttta atgcaaccta ataggaaatt 350

 attattcgag acagactcct ctgggaaatg cataacccag gaggcactga 400

 ttccttgctg agaatcctga gtggtctgtc attttaccta agatcacatc 450

 cttcaaacat tgtgtatgtt ggagcagcga aagaactgtt caccccttat 500

 gaataactga cattcaggaa gcccaactcc atcatgcaga tgtctatctt 550

 taattgctag ctcagaagca gacagagctt cctgggacct ggctaaagta 600

 actgatagat ggaactcttc tttggggact attactttgc aaatggggtc 650

 agagcctcat ctatgcagag aatgtcacca tatgtggttt catgtaatct 700

 gtaattattt gttccaacag cctttaacat gactattgtt tgagaaacat 750

 ggcaactttt aattcccctt tgatgcttct agctttcttt agtattttaa 800

 gaactcatac agtactaggt atgttggtcc ctctgagaaa aacatgtgga 850

 ctctcaccag tccgttgtgc tcaggactga gcagcagcgt gtgtgcgggg 900

 cagctgtgga ggtgaatact gattgtcccc cttttcctcc acagggatat 950

 ctgcattacc tccacctcct ccacctccac caccaccagc agctcccttg 1000

 cctcctgcga gcaccgaggt acctgcccag ctctcgtctc aggctgtgaa 1050

 tggcatgagc cgaggggcct tgctcagctc catccagaat ttccaaaaag 1100

 gaactttgag gaaagccaaa acctgtgatc acagtgctcc gaagatcggc 1150

 tgaagcttcc tgtttacact tggagggaaa agttcttttt tattcctact 1200

 cacccctacc ccccaaacta ccctcttcct gggaaagtaa ttgctgagcc 1250

 agtacagcca caaacagtac tattttgcag atgctcatgt aagcagcttt 1300

 tcgagagaaa taattcttta agcagaataa agttaggctg gcattgctcc 1350

 cttaagatct tgctccttta ttaaccctgt aaagggagtc ttgtttatcc 1400

 tctaatggcc aggcttttgg gacagcagca tattgaaata ttttcaccaa 1450

 ctaaaggaaa tagacagaaa aacaatgaca atattcaatc acagcagtaa 1500

 atggcctttg tgttgcaatc ccttctaccc catcagacag ctcctagaaa 1550

 cattcctctt acagttcatt tctctaaagc attttctgat tcttagataa 1600

 ctccaatttt tgctaccttt atcttagaca ttaacactat agcccaaagc 1650

 atagttactt tgctaaatca gaaagcaact gagttctttg ttttctcctc 1700

 aaatagaatg gggaacgttc acaacattct cttaagttct aacaggaata 1750

 ccattgtggt tatagaactc agggctgcta aagcaactac tctagaccca 1800

 tagttctttt tagttagatg tattgaaaca gacaaaaata ttaacatcag 1850

 aaaaagctct tgccaattag aggatcttct taatcctcag caattaagtt 1900

 tggggtttga ggggggcagg tcattgttac aacagaagta aatttggcat 1950

 ctatagaaat caattatgat ttttgaaaga tttatctaaa tatatcaata 2000

 tagcatctct ttaatgttag tcatttatta gaaagatcct ttatcctgat 2050

 ttgcttaaac ctttcaataa attgcacttt aaaggattat aaataatcca 2100

 tttaaaaatt caagtacaca catcagtgtt ggttactatg cagagaatgt 2150

 cattgtgtat agtttcatgt aatctgttat gtcagctgta tttttaaatg 2200

 gattatttat aatcctttaa agtgcaattt attgaaaggt ttaagcaaat 2250

 caggataaag gatctttcta ataaatgact aacattaaag agatgctata 2300

 ttgatatatt tagataaatc tttcaaaaat cataattg 2338

<210> 4264
<211> 76
<212> PRT
<213> Homo sapien

<400> 4264
 Leu Asn Ser Gly Val Ile Cys Pro Glu Arg Thr Phe Met Ile Leu
   1               5                  10                  15

 Lys Tyr Lys Ile Arg Val Ala Asn Val Met Cys Leu Glu Ala Glu
                  20                  25                  30

 Gly Ser Phe Arg His Leu Pro Ser Phe Pro Leu Leu Pro Thr Val
                  35                  40                  45

 Val Gln His Asp Ile Leu Val Ser Pro Asp Ala Ser Ser Lys Thr
                  50                  55                  60

 Phe Ser Ala Val Met Ser Cys Ser Leu Val Gly Pro Gln Trp Arg
                  65                  70                  75

 Glu


<210> 4265
<211> 492
<212> DNA
<213> Homo sapien

<400> 4265
 ggcacgaggg tacatcattg ggaatggagg gaaataaatg actggatggt 50

 cgctgctttt taagtttcaa attgacattc cagacaagcg gtgcctgagc 100

 ccgtgcctgt cttcagatct tcacagcaca gttcctggga aggtggagcc 150

 accagcctct ccttgaataa ctgggagatg aaacaggaag ctctatgaca 200

 cacttgatcg aatatgacag acaccgaaaa tcacgactca gccccctcca 250

 gcacctctac ctgttgcccg ccgatcacag ccggaatgca gctgaaagat 300

 tccctggggc ctggttccaa ccgcccactg tggactctga ggcctctgca 350

 tttgcgggtg gtctgcctgt gatattttgg tcatgggctg gtctggtcgg 400

 tttcccattt gtctggccag tctctatgtg tcttaatccc ttgtccttca 450

 ttaaaagcaa aactaaagaa aaaaaaaaaa aaaaaaaaaa aa 492

<210> 4266
<211> 52
<212> PRT
<213> Homo sapien

<400> 4266
 Met Thr Asp Thr Glu Asn His Asp Ser Ala Pro Ser Ser Thr Ser
   1               5                  10                  15

 Thr Cys Cys Pro Pro Ile Thr Ala Gly Met Gln Leu Lys Asp Ser
                  20                  25                  30

 Leu Gly Pro Gly Ser Asn Arg Pro Leu Trp Thr Leu Arg Pro Leu
                  35                  40                  45

 His Leu Arg Val Val Cys Leu
                  50

<210> 4267
<211> 4574
<212> DNA
<213> Homo sapien

<400> 4267
 ccaaaacaaa acttttcttt acttaagccg tcccagagga agtcctgctg 50

 cagaaaagat gatagaattg gtcacccaat caatagctgt gaagacttcc 100

 ttattcctgc tgaacttcct tccttggata tcttcatgga taagcctgtg 150

 tctgtggaca gagtggggcc caagtgctga ggctcgaaag acaggtttta 200

 caatcagcca attaaacatc ttaccagttg ctgtacccct tgccaagggg 250

 atgagctgag gagcttcttt tctttaggtc caacatcaaa atgagtccat 300

 ctgagctagg gctttttgca aaggtgatta aaaatcaagg ctggagttcc 350

 agccaaatag ggaggagagg taccacaagt tcatcttaaa cttgcttccg 400

 ggctgggtag ttaaaacagg aagatcccaa ggggatctta cgaggcaaat 450

 atcagcaggt aactgtggaa gaaaggaaat ctcaggacct aatgagttcg 500

 ttgtaaaata ttcctgggaa tagatggggg atctactccc agttttttac 550

 tttttacaga atattgttgc tttcctacaa caatgtacat atatttgcag 600

 ttgtatatgc tttttttttt tccaaataaa cttgtcaccc tgcatgccct 650

 tggcaaataa gtgaagcaga aataggaaca cagtccacat tcaagttgag 700

 gaacagtgta tctttaagag ctgacctttg ggtgacctgg aaagggggaa 750

 agatggctaa gcatggagag aaacgaggca agagacaagc tatgatacaa 800

 caccgcttca gcccctgccc tcaatagcac acaacccaca tatcagcttt 850

 ctgaagagaa ggaacctact gtttagtgct cctcactttg caatgtttgt 900

 gctacgccag aatttctcca gtttttttca ttatcatccc cctgagaaaa 950

 aaattacatt gaatttaaat tttccctaat aagagaaatt aaatatgaaa 1000

 gaataggatt ttgttgggta agattgagct ttggaaggtc acgaaccatt 1050

 attctatcta aggtgtgtgt tttgttttgt ttttttttgt ttttttttgg 1100

 caatccctct ccccctgaac caatttcaca ttgggaatgc aggacctaga 1150

 ctgctgaata aaaagctact tcttctataa ttgtcaggtt ctctccaatt 1200

 tctcagcttc ctcaaagaca tggggtggag ttgggtgtgc catcactgag 1250

 agagctctgg aacttttgac tcttagtgac atttttagat ttaggggttc 1300

 atggccttcc acatgttgcc accaactggt gatctctgcc ccttcatgct 1350

 gatcaagaaa gtagaaactc ctcgtcgcct tcaggtttgc agtcgcagaa 1400

 acattgcctg ctgtggactg tcagcacaaa actgggacac tggtgtcatt 1450

 tagactgtca gcagtgcaca tgattgtacg atagactcca ggcaaccatg 1500

 tgcatctgtg caagatgacc tctgccccaa gagaagggtt acggtctaat 1550

 taaatgttta ccaagatggt accagtgggc tctccccgtg tcctttggtg 1600

 ttattggagc tggtgtatga cagactcaag gaaatttttt aaggaaaatg 1650

 aagaagaaat caacctttat ggttctcttt cattggaaga ggagaataag 1700

 gaaagaaatg gcaggtagag agggaggggg aaaggaatag aaatggcatg 1750

 tctttgatgc tgtggcttgt gtggggacaa tgggaagagc acagcaggca 1800

 caacatatct gtgttagtgc cacgtggtat ctgttaagta tggccagagc 1850

 ctcacatata agtgaagaga gttaagacaa ttcttgctct ttgaacaata 1900

 atagtctata gaatttctat tggcaaacca tcccagacaa cctgacctat 1950

 caaacaaaag caaataatcc ctgtctcaga actgctggtc taaaagctag 2000

 aaggggcatg ataatggaaa ttgctagaaa agagagaatg ctctactctc 2050

 tttcctgtgc ctacctaccc ccatcctaaa ccctgtaaaa cagaatttca 2100

 aaatagatgt caaatatgaa gtaattcaga cttccaaaga aggaaagagt 2150

 tctgcccagg gcagtatgag caaatccaca gggatgttaa gatttggtcc 2200

 aactcaaagg tttatgggca gtgagcctag agtctcttga gagtaaaccc 2250

 ttgcatttgg gacaaggaga atatgtgaag ttcaggagtg ctcacactag 2300

 agcaagatcc agaaaaaaaa aaatccaatg gcattttaaa ctagattgca 2350

 ttatcactca atgctgttac tttgagcaga caaatcagtt gaatgggagg 2400

 gcaaatggca gaaatgaaca aaagctatta ggtgaaagca tccccaatgt 2450

 atcagttgtg agatgatttt tgtttaatga tgatcaggtt tacattgaag 2500

 tggcttggaa gacgtatttc agagggactg ggtttgtact gcaaaactct 2550

 gaacactaga gcaggttcta ctagcacttg ggcagtaagg tagcgggtgt 2600

 gtattatgct attgccatag ttctcgtctt tgtggattca catacccttt 2650

 cccatgagga gcttgctact aacagcctcc tgtttctgtt gtttttatat 2700

 gggagaagag aaagagcttg gaatttcaat tgtctaaaca attggtatga 2750

 tttacaagaa ggcaaaccat tcaggagatg ttcaacagtg tatcattctt 2800

 agcattcaat acaatgttta ttataaaata tacacctgag tttatgtttt 2850

 tctgccaggc tgaagggcaa taatgtcttg ctatgcaaac actctatttt 2900

 atgtgtgaat ttttttaact gtaattttat gtgtgaattt ttttaactaa 2950

 actctatcat cattttctat gttgacatct tttttttttt ttaatctgtt 3000

 tccaactctg agtctgtgaa ctatctcttc tgactggatg ctggcctaaa 3050

 atcctattag tgcttaaaca gacctcaaaa cactctgaac ctgtaggcca 3100

 atacagagat gttgttcttt gatatatctt gggtccttga tggcttcaac 3150

 aaacaaggtc ataatttgtt taaattcagt gttttctgta gataccttct 3200

 tctcagtttc attaagaaga gtaaccatct ttggttttcc aaagaatgga 3250

 aactcctacc ctagacttta gacttagagc gtctgccttt cacgatgagt 3300

 aagagatcca gaatgtttag gggatgtgcg tcagcccacc tggtacagtg 3350

 gcaaagctga atgcgaactt gaggcctcct gaggcctgac cttctatgcc 3400

 cccagccctc caccccaagc accttttggt gtggctggaa acacatgaca 3450

 ttggatgtga tttttctcaa gcccttcact gtggaaggca tgggagactg 3500

 cccagcattg ggcatgtggc tgttaacgtt tccatttcaa gtccctgatt 3550

 cttactggag aagttaagga gccacttaat gttttcacag acctctgatt 3600

 ctgttgtgaa tgtggcattc cagtgagtac aacctgcttg ctataaagaa 3650

 agcagcatat tttgacaatt ttatttcttc cttgggtact tacattttta 3700

 ttacaaaaat ggccgttata aaaaaagaca gaagggctgg gcagtggctt 3750

 gctccctaga aactgagatt ccgaagcagg tgtttcctct cccctagact 3800

 cagaggtaca tttaatccat cttctccatt tcctccttca ggaccagcta 3850

 tgagattcag tgcatttcta gcccagcgga tgttcattct ccactaaact 3900

 tcatctttta ctaagcaaag ggggattatt ccatgaggca gccaggagca 3950

 aggggccatg atattcatga ctttgtctgc tgggcatttt tcaaagtgtc 4000

 cttgaattca ctcagcaaac aaagctttct ggagaatctc tcaaaactta 4050

 ggccctgctc catttggcca aaaatgatgg ctgctccaaa actctgaact 4100

 tcttaaaact ccatctgcta cattatttct ggagtttaaa catgactttt 4150

 tctgtctttg agtatagatg tgtttgttta attaacgaag cacaagtctg 4200

 ttaagcagaa ggctccaagc tgtattctat acttgggaat ccttggtgcc 4250

 atctttattc taccaagtgc caatcaccat ggctaaagtg ggcgtatatt 4300

 acagcctgtg tcctaagctt agaagcttta atgtactttt ttaaatgaaa 4350

 agtattagag ggggttgaac attgtaacta aagcataaag ttagaccaat 4400

 tacatgcaga gatgtttatt taatattgtg tgagctgagt ccttctgtat 4450

 aaattatttg cacacttttc ttgcatgatg aactgatttt ttatagttgt 4500

 ttgtaccaga cggtggcata tttttgtaaa aaacttttga cactgaattg 4550

 caataaatgt ttttccaaca acac 4574

<210> 4268
<211> 85
<212> PRT
<213> Homo sapien

<400> 4268
 Gln Asn Lys Thr Phe Leu Tyr Leu Ser Arg Pro Arg Gly Ser Pro
   1               5                  10                  15

 Ala Ala Glu Lys Met Ile Glu Leu Val Thr Gln Ser Ile Ala Val
                  20                  25                  30

 Lys Thr Ser Leu Phe Leu Leu Asn Phe Leu Pro Trp Ile Ser Ser
                  35                  40                  45

 Trp Ile Ser Leu Cys Leu Trp Thr Glu Trp Gly Pro Ser Ala Glu
                  50                  55                  60

 Ala Arg Lys Thr Gly Phe Thr Ile Ser Gln Leu Asn Ile Leu Pro
                  65                  70                  75

 Val Ala Val Pro Leu Ala Lys Gly Met Ser
                  80                  85

<210> 4269
<211> 1530
<212> DNA
<213> Homo sapien

<400> 4269
 agcactcccg gagcctgcaa cgcttgagat cctctccgcg cccgccaccc 50

 cgcagggtgc cccgcgccgt tcccgccgcc ccgccgcccc cgtcgcgggc 100

 ccctgcaccc cgagcatccg ccccgggtgg cacgtccccg agcccaccag 150

 gccggccccg tctccccatc cgtctagtcc gctcgcggtg ccatgccatt 200

 cctcgggcag gactggcggt cccccgggca gaactgggtg aagacggccg 250

 acggctggaa gcgcttcctg gatgagaaga gcggcagttt cgtgagcgac 300

 ctcagcagtt actgcaacaa ggaggtatac aataaggaga atcttttcaa 350

 cagcctgaac tatgatgttg cagccaagaa gagaaagaag gacatgctga 400

 atagcaaaac caaaactcag tatttccacc aagaaaaatg gatctatgtt 450

 cacaaaggaa gtactaaaga gcgccatgga tattgcaccc tgggggaagc 500

 tttcaacaga ctggacttct caactgccat tctggattcc agaagattta 550

 actacgtggt ccggctgttg gagctgatag caaagtcaca gctcacatcc 600

 ctgagtggca tcgcccaaaa gaacttcatg aatattttgg aaaaagtggt 650

 actgaaagtc cttgaagacc agcaaaacat tagactaata agggaactac 700

 tccagaccct ctacacatcc ttatgtacac tggtccaaag agtcggcaag 750

 tctgtgctgg tcgggaacat taacatgtgg gtgtatcgga tggagacgat 800

 tctccactgg cagcagcagc tgaacaacat tcagatcacc aggcctgcct 850

 tcaaaggcct caccttcact gacctgcctt tgtgcctaca actgaacatc 900

 atgcagaggc tgagcgacgg gcgggacctg gtcagcctgg gccaggctgc 950

 ccccgacctg cacgtgctca gcgaagaccg gctgctgtgg aagaaactct 1000

 gccagtacca cttctccgag cggcagatcc gcaaacgatt aattctgtca 1050

 gacaaagggc agctggattg gaagaagatg tatttcaaac ttgtccgatg 1100

 ttacccaagg aaagagcagt atggagatac ccttcagctc tgcaaacact 1150

 gtcacatcct ttcctggaag ggcactgacc atccgtgcac tgccaataac 1200

 ccagagagct gctccgtttc actttcaccc caggacttta tcaacttgtt 1250

 caagttctga atcccagcac atgacaacac ttcagaaggg tccccctgct 1300

 gactggagag ctgggaatat ggcatttgga cacttcattt gtaaatagtg 1350

 tacattttaa acattggctc gaaacttcag agataagtca tggagaggac 1400

 attggagggg agaaatgcag ttgctgactg ggaatttaag aatgtgaact 1450

 tctcactaga attggtatgg aaaagcaaaa tactgtaaat aaactttttt 1500

 tctaacaatt tgccaaaaaa aaaaaaaaaa 1530

<210> 4270
<211> 355
<212> PRT
<213> Homo sapien

<400> 4270
 Met Pro Phe Leu Gly Gln Asp Trp Arg Ser Pro Gly Gln Asn Trp
   1               5                  10                  15

 Val Lys Thr Ala Asp Gly Trp Lys Arg Phe Leu Asp Glu Lys Ser
                  20                  25                  30

 Gly Ser Phe Val Ser Asp Leu Ser Ser Tyr Cys Asn Lys Glu Val
                  35                  40                  45

 Tyr Asn Lys Glu Asn Leu Phe Asn Ser Leu Asn Tyr Asp Val Ala
                  50                  55                  60

 Ala Lys Lys Arg Lys Lys Asp Met Leu Asn Ser Lys Thr Lys Thr
                  65                  70                  75

 Gln Tyr Phe His Gln Glu Lys Trp Ile Tyr Val His Lys Gly Ser
                  80                  85                  90

 Thr Lys Glu Arg His Gly Tyr Cys Thr Leu Gly Glu Ala Phe Asn
                  95                 100                 105

 Arg Leu Asp Phe Ser Thr Ala Ile Leu Asp Ser Arg Arg Phe Asn
                 110                 115                 120

 Tyr Val Val Arg Leu Leu Glu Leu Ile Ala Lys Ser Gln Leu Thr
                 125                 130                 135

 Ser Leu Ser Gly Ile Ala Gln Lys Asn Phe Met Asn Ile Leu Glu
                 140                 145                 150

 Lys Val Val Leu Lys Val Leu Glu Asp Gln Gln Asn Ile Arg Leu
                 155                 160                 165

 Ile Arg Glu Leu Leu Gln Thr Leu Tyr Thr Ser Leu Cys Thr Leu
                 170                 175                 180

 Val Gln Arg Val Gly Lys Ser Val Leu Val Gly Asn Ile Asn Met
                 185                 190                 195

 Trp Val Tyr Arg Met Glu Thr Ile Leu His Trp Gln Gln Gln Leu
                 200                 205                 210

 Asn Asn Ile Gln Ile Thr Arg Pro Ala Phe Lys Gly Leu Thr Phe
                 215                 220                 225

 Thr Asp Leu Pro Leu Cys Leu Gln Leu Asn Ile Met Gln Arg Leu
                 230                 235                 240

 Ser Asp Gly Arg Asp Leu Val Ser Leu Gly Gln Ala Ala Pro Asp
                 245                 250                 255

 Leu His Val Leu Ser Glu Asp Arg Leu Leu Trp Lys Lys Leu Cys
                 260                 265                 270

 Gln Tyr His Phe Ser Glu Arg Gln Ile Arg Lys Arg Leu Ile Leu
                 275                 280                 285

 Ser Asp Lys Gly Gln Leu Asp Trp Lys Lys Met Tyr Phe Lys Leu
                 290                 295                 300

 Val Arg Cys Tyr Pro Arg Lys Glu Gln Tyr Gly Asp Thr Leu Gln
                 305                 310                 315

 Leu Cys Lys His Cys His Ile Leu Ser Trp Lys Gly Thr Asp His
                 320                 325                 330

 Pro Cys Thr Ala Asn Asn Pro Glu Ser Cys Ser Val Ser Leu Ser
                 335                 340                 345

 Pro Gln Asp Phe Ile Asn Leu Phe Lys Phe
                 350                 355

<210> 4271
<211> 1803
<212> DNA
<213> Homo sapien

<400> 4271
 ggaagggatg tcttaaaaga ggagaagctt taaattagac gatcggagaa 50

 ggctgaggga attgctatga aggggcggga gctgaagtgt agaggactcc 100

 tttagacagc agaaagggaa agccgttgag aagttccctt caaactccac 150

 ctgcctcctc tccaattcaa actccactcc cttctccaaa agttaaaagg 200

 aaagccaagt ttgccacgct cccctgttcc tactcaataa atacttcttc 250

 tactccgcca ccgggaaaac agaaaaaaaa aactaatttc cttcccaata 300

 ttaggactta gaaaagctct aggtcccgca acttgaattt tagcctaggg 350

 gaatcaaaat agtaggagca ttactcttgt ttcctttttc aaaatcccac 400

 acctcatcct tcctgcgacg ccatgtctac caacatttgt agtttcaagg 450

 acagcgcagt ggacttcact ggaagatgct atttcaccaa aatctgcaaa 500

 tgtaaactga aggacatcgc atgtttaaaa tgtgggaaca ttgtaggtta 550

 tcatgtgatt gttccatgta gttcctgtct tccttcctgc aacaacggac 600

 acttctggat gtttcacagc caggcagttt atgatattaa cagactagac 650

 tccacaggtg taaacatcct actttggggc aacttgccag agatagaaga 700

 gagtacagat gaagatgtgt taaatatctc agcagaggag tgtattagat 750

 aaatggaatt atgatatata tgatatacaa acttttttct atttaaaaat 800

 atattaatgg atcaacttta aaattgttag ttgccagtga tcttttttgg 850

 aaaacaaaaa tggggcattt gttgatttat ttattttccg tctctaatta 900

 gttacctcag tttgattgaa gccagtggag ttgtgctttt cctctacttc 950

 tacttcctct cccccacctt tttctgccca gtgtaggtgt attcttaaat 1000

 tcagacggga agattctttc acatatcact cagttacctc ccaatctggg 1050

 ggagtttttc ttacaacttg ataccagata ccattaattt tacattcctg 1100

 aataaaggcc tagtacccac gcatatttca accatgcata tatcaagttc 1150

 aactgagttt taatagggga ttaaaaaaac aagctgttag gtttccatgg 1200

 gcactggttc tcataggttc tattggtgat aactgcttta acatggagca 1250

 agagtttgtg aatcaggaaa tagaataaat taaaatttaa aatatataga 1300

 ggaatcctct tgattgctca gcatgatgtt agataaatga gtttgtcaga 1350

 aaatatcagt atacgctgtt taccaatgtt atttatttac attcttctaa 1400

 agccattatg gatattgtat tatgagagct aaacctaaat aagttatcct 1450

 gttccctagg accttctctg taaatagtga attttagacg agtagtctgt 1500

 cctaaatctt aaatagaaaa aaaactaaag cgatttgctt aagccattgt 1550

 acattataaa gagctgtttt gttttgcttt gctttgcttt gttttgtttt 1600

 tttaaagctg cattcagagc cacaaaggaa taggaaagta gggtagtgtt 1650

 ggattctggt tttatgtaac tctaaaataa atgtatctct ttaatatctc 1700

 agttgtaggg attttgtcaa taccaaagca gactgagttg tggttttgta 1750

 aataaagttt tttctaaaaa tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaa 1803

<210> 4272
<211> 109
<212> PRT
<213> Homo sapien

<400> 4272
 Met Ser Thr Asn Ile Cys Ser Phe Lys Asp Ser Ala Val Asp Phe
   1               5                  10                  15

 Thr Gly Arg Cys Tyr Phe Thr Lys Ile Cys Lys Cys Lys Leu Lys
                  20                  25                  30

 Asp Ile Ala Cys Leu Lys Cys Gly Asn Ile Val Gly Tyr His Val
                  35                  40                  45

 Ile Val Pro Cys Ser Ser Cys Leu Pro Ser Cys Asn Asn Gly His
                  50                  55                  60

 Phe Trp Met Phe His Ser Gln Ala Val Tyr Asp Ile Asn Arg Leu
                  65                  70                  75

 Asp Ser Thr Gly Val Asn Ile Leu Leu Trp Gly Asn Leu Pro Glu
                  80                  85                  90

 Ile Glu Glu Ser Thr Asp Glu Asp Val Leu Asn Ile Ser Ala Glu
                  95                 100                 105

 Glu Cys Ile Arg


<210> 4273
<211> 1368
<212> DNA
<213> Homo sapien

<400> 4273
 gcattcactg agtgtgcttc tacatctaat cacctcagtt tgcagaatgc 50

 atatgggggt gagagcaaga gccagtgtta tctgttgggc accataagca 100

 cagtgcatac gggcccacag tgctctttgg gggacccatg aaaatgatct 150

 ttaatcttct tattaaaatc aaaagacgaa aaaatttggc tgggattatc 200

 aggtgcgagc cactgcgcct ggctggtttt catgaatctt gatagacatc 250

 tataacgtta ttattttcag tggtgtgcag catttttgct tcatgagtat 300

 gacctaggta tagagatctg ataacttgaa ttcagaatat taagaaaatg 350

 aagtaactga ttttctaaaa aaaaataaaa aaaaatttct acattataac 400

 tcacagcatt gttccattgc aggttttgca atgtttgggg gtaaagacag 450

 tagaaatatt attcagtaaa caataatgtg tgaactttta agatggataa 500

 tagggcatgg actgagtgct gctatcttga aatgtgcaca ggtacactta 550

 cctttttttt tttttttttt ttaagttttt cccattcagg aaaacaacat 600

 tgtgatctgt actacaggaa ccaaatgtca tgcgtcatac atgtgggtat 650

 aaagtacata aaatatatct aactattcat aatgtggggt gggtaatact 700

 gtctgtgaaa taatgtaaga agcttttcac ttaaaaaaaa tgcattactt 750

 tcacttaaca ctagacacca ggtcgaaaat tttcaaggtt atagtactta 800

 tttcaacaat tcttagagat gctagctagt gttgaagcta aaaatagctt 850

 tatttatgct gaattgtgat ttttttatgc caaatttttt ttagttctaa 900

 tcattgatga tagcttggaa ataaataatt atgccatggc atttgacagt 950

 tcattattcc tataagaatt aaattgagtt tagagagaat ggtggtgttg 1000

 agctgattat taacagttac tgaaatcaaa tatttatttg ttacattatt 1050

 ccatttgtat tttaggtttc cttttacatt ctttttatat gcattctgac 1100

 attacatatt ttttaagact atggaaataa tttaaagatt taagctctgg 1150

 tggatgatta tctgctaagt aagtctgaaa atgtaatatt ttgataatac 1200

 tgtaatatac ctgtcacaca aatgcttttc taatgtttta accttgagta 1250

 ttgcagttgc tgctttgtac agaggttact gcaataaagg aagtggattc 1300

 attaaaaaaa tctatgtcgg gtgcggagaa agaggtaatg aaatggcagg 1350

 aattcgatat cagcttat 1368

<210> 4274
<211> 46
<212> PRT
<213> Homo sapien

<400> 4274
 Ala Phe Thr Glu Cys Ala Ser Thr Ser Asn His Leu Ser Leu Gln
   1               5                  10                  15

 Asn Ala Tyr Gly Gly Glu Ser Lys Ser Gln Cys Tyr Leu Leu Gly
                  20                  25                  30

 Thr Ile Ser Thr Val His Thr Gly Pro Gln Cys Ser Leu Gly Asp
                  35                  40                  45

 Pro


<210> 4275
<211> 2653
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 367-438, 548-601
<223> Unknown base

<400> 4275
 gggagttgca gggggagaga tggaaaggct agcagctgaa aaaaaatagg 50

 taaataacca gtgtattcca tgtagctgtt aatctagttt gttgcttcca 100

 tcagctgcag gagtattcca tagtatgcat ccaccatagt aaatttatcc 150

 attcacctgg ttgcctcaaa ttcttggcta cctggagaaa ttaaaaccct 200

 tgaagctagg gttctgagta caagatcagt tccaccaatt agatttcttc 250

 atttgagatt tgggaggtaa aggctgtctt tctgctgttt gggttgttgc 300

 tgctggaaag caagtttatg tacatatggg gctttctgca acagctttcc 350

 agctttgaaa acctgcnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnca ttcaacaggt 450

 aaaataaatc tactctgtaa tagtataagt ttgactacaa taaactgtgg 500

 ttaagaagaa aaattggccg ggcatggtgg ctcatgcctg cctgtaannn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nccagagtaa tggtttcttg actttctgta gcccttgttc cttagtctgc 650

 tgtgatattt atgttgacct ttatcatttt ctattctgaa cccctcttag 700

 catttaatgt gaaatctaag aaattagaag tagaatggct tttattgttt 750

 tgacaccttt gaaattatta ttaataattt ttccagagca aaaaagcaaa 800

 cacgctcaat aagactaaac aaaacaaaat ataaatgtac atcatttaat 850

 gtcccagtgg ctctattcta cctgtaagaa aatgatacaa aaccacctaa 900

 gatattttga agcctgacaa atcagcttca tggaaaaagg taaaaaatgc 950

 atttttcaac cgaaagggca gatccaatag aagacccgct ccttaaataa 1000

 acataaaatg taaaaagttg gaaaattaag agtaatgttc catctggaaa 1050

 ctgaactttt gtccttgaac ttgtgttggc accaagcctc atacacagtg 1100

 agctcaataa ctgttgggac aaaggaagga aggacaaaat gtgtaacttc 1150

 ccagcatctg ggagatgctg tctcttgcct cactgagtgt tccttttctt 1200

 tgctctcatg tcattccctg agaacaatga attctgggac aggctaaaca 1250

 tcatgatgaa gtttcttaaa cagactttct tagtggaaat ccatttagat 1300

 ctgggtgtgc tctatgggga gtgctgacgt caaagagcaa atgtctataa 1350

 ggggcccttt taaaatgaac attttcctca ttgagcaagc tgggattctc 1400

 taatgtagaa atcaagccat ctttataatt tcacttcaga tgtttatgtt 1450

 tttgtttttt tttgtctcca atgatggtaa aaataaaaac tacgcattac 1500

 ttaaaggagt ttccctcaca tgtaaacact gttaggaagt ctggattaag 1550

 ttgaaagtcc tgttttaact ttttttctct catataccaa acactctgta 1600

 tttctcttaa agaagccctt taagagaaag ccctaatttt atatctgaca 1650

 gtaaagtttg ctgcaagtgt atgagttcaa acacatccct tgttttctgt 1700

 ccctagggga aaagtcatgt agttttagct tggctccagt gttaatatta 1750

 tattcagtag cagccttaga agagtggtct aagacttgaa cctggagcaa 1800

 ttttatagca cagaatccta cgaagatagg actgtgaaca tttgttttct 1850

 ttttcgtgtg tgtcaaacta actggttttt gctttaccaa taaaatgtcc 1900

 tcggcagagt aaattttaaa cgtgaaaatt atagatcttg atattgaatc 1950

 catcagtgat tcaagagata cacctatttg cctaaaacaa cctaagatgt 2000

 attggttatg gaatcatgtg ttggataggt tcttaagacc tgtttcctca 2050

 aatcttgaca cagttttcaa gggtggctta ttgacttgca cggttgggca 2100

 gataatccag atttacctaa gattgggtaa aaaagtcatc tgtgactttg 2150

 ctggcagggc atttgctaag tggagtacag gatctaaaag ggttttctta 2200

 gaaagggcaa tattgtccaa tgaagtaagc agaaggactc tgggttagaa 2250

 gcatctgcac aaaaactggt gagacctact ctccactgct ctgcagctgg 2300

 atggctgatg gcaggctgag cagtggggaa gcaggtttta acaacaggga 2350

 gtccttccag gtcactgtat attgagaaga aacataaaac tattgtctgt 2400

 tacattccga ggtcagcctt cttcttaacg ttttataata tgcaaatgcc 2450

 agcttctgga aagcaagtat catcatgtac caaatgcttt atacaccatc 2500

 acattcatga attttttagc atggtcagaa cttgtgtaaa tatgtctctt 2550

 agatgatttt ggggagatgt gatttatttt tcatattttc aaaatgcatt 2600

 tcatttcaaa taaagttatc tattgagaca accgaaaaaa aaaaaaaaag 2650

 cgg 2653

<210> 4276
<211> 33
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 367-438, 548-601
<223> Unknown amino acid

<400> 4276
 Met Ile Leu Gly Arg Cys Asp Leu Phe Phe Ile Phe Ser Lys Cys
   1               5                  10                  15

 Ile Ser Phe Gln Ile Lys Leu Ser Ile Glu Thr Thr Glu Lys Lys
                  20                  25                  30

 Lys Lys Ser


<210> 4277
<211> 717
<212> DNA
<213> Homo sapien

<400> 4277
 gcacgagggc tacggccctg gaacggggcc atggagaagc tgcggcgagt 50

 cctgagcggc caggacgacg aggagcaggg cctgactgcg caggtcctgg 100

 atgcctcatc ccttagtttc aacaccagat tgaaatggtt tgccatctgc 150

 ttcgtatgtg gcgttttctt ttctattctt ggaactggat tgctgtggct 200

 tccgggcggc ataaagcttt ttgcagtgtt ttataccctc ggcaatcttg 250

 ctgcgttagc cagtacatgc tttttaatgg gacctgtgaa gcaactgaag 300

 aaaatgtttg aagcaacaag attgcttgca acaattgtta tgcttttgtg 350

 tttcatattt accctgtgtg ctgctctttg gtggcataag aagggactgg 400

 ctgtgttatt ctgcatattg cagttcttgt caatgacctg gtatagcctg 450

 tcatacatcc catatgcaag ggatgcagtt attaaatgct gttcttctct 500

 cctaagttga aaatcagaaa cttgtggaaa agagcacttg aatgttggta 550

 ctctatgttt ggtgaagttt gcttttcccc ataaaacact ccaggaacaa 600

 ctgacgtgac agttgaagac cgttttgtac taagtctcat tttgtatact 650

 ggtaaaaact acatgcttga ttaaaccatt aaatgcttgt aactttaaaa 700

 aaaaaaaaaa aaaaaaa 717

<210> 4278
<211> 159
<212> PRT
<213> Homo sapien

<400> 4278
 Met Glu Lys Leu Arg Arg Val Leu Ser Gly Gln Asp Asp Glu Glu
   1               5                  10                  15

 Gln Gly Leu Thr Ala Gln Val Leu Asp Ala Ser Ser Leu Ser Phe
                  20                  25                  30

 Asn Thr Arg Leu Lys Trp Phe Ala Ile Cys Phe Val Cys Gly Val
                  35                  40                  45

 Phe Phe Ser Ile Leu Gly Thr Gly Leu Leu Trp Leu Pro Gly Gly
                  50                  55                  60

 Ile Lys Leu Phe Ala Val Phe Tyr Thr Leu Gly Asn Leu Ala Ala
                  65                  70                  75

 Leu Ala Ser Thr Cys Phe Leu Met Gly Pro Val Lys Gln Leu Lys
                  80                  85                  90

 Lys Met Phe Glu Ala Thr Arg Leu Leu Ala Thr Ile Val Met Leu
                  95                 100                 105

 Leu Cys Phe Ile Phe Thr Leu Cys Ala Ala Leu Trp Trp His Lys
                 110                 115                 120

 Lys Gly Leu Ala Val Leu Phe Cys Ile Leu Gln Phe Leu Ser Met
                 125                 130                 135

 Thr Trp Tyr Ser Leu Ser Tyr Ile Pro Tyr Ala Arg Asp Ala Val
                 140                 145                 150

 Ile Lys Cys Cys Ser Ser Leu Leu Ser
                 155

<210> 4279
<211> 838
<212> DNA
<213> Homo sapien

<400> 4279
 gcttccttgt cgtgtggcct cagtccttcg ccgtccctcg ccgtccttcg 50

 ccatcgcacg ccaccgcacc ccatctctcg aaatctgcag acatcttgat 100

 ttttcccacg ctgtctgtca ggtctccgcc gccactcgac gccagggcgc 150

 cgggccttgt gggctgtgct gcacctcgga cggcttcgca ccagccagcg 200

 ccctctctct cctgcagcac tctgatctgc accccctgag gggcttccac 250

 tgtccgcggg gtgagaatgc ccctgggagt gtcacatgac tgccgcccca 300

 tgtgtgtgag aggcgtcctc tgggagagca tggatcctga ggtcccagga 350

 ttgtcagctg acctctgtcc tgtgtgccca gtggccccag gtgacgtgtc 400

 ttcaagaaga ggctgagctg cggtgcttgt aaggtctcag ccttagatcc 450

 aaggacagtc caaggaagtc ctaagaccat ggagttggtg atctgggatc 500

 tgggtttgct gatatttctc accgtgaatc tcttggtggt gtttgtgggc 550

 acgagagggg cagagaatgg agagtgaggc taccacatga agcgtcacca 600

 gagctgctcc ctgctgcctg ctcagagcac cccggatcca ctgttcaatc 650

 tgcacaagat tcggggtcca gacatgggag acttcagctg cctcagagga 700

 ccgtggacag ggaaggccag cctcgcatcc ctctgtccat gcctggaatg 750

 actttaataa ccaagagttt tatttttgaa tttgtagctg tcgttcactt 800

 tttacccacc cattcaataa accttacaga attgctcc 838

<210> 4280
<211> 95
<212> PRT
<213> Homo sapien

<400> 4280
 Leu Pro Cys Arg Val Ala Ser Val Leu Arg Arg Pro Ser Pro Ser
   1               5                  10                  15

 Phe Ala Ile Ala Arg His Arg Thr Pro Ser Leu Glu Ile Cys Arg
                  20                  25                  30

 His Leu Asp Phe Ser His Ala Val Cys Gln Val Ser Ala Ala Thr
                  35                  40                  45

 Arg Arg Gln Gly Ala Gly Pro Cys Gly Leu Cys Cys Thr Ser Asp
                  50                  55                  60

 Gly Phe Ala Pro Ala Ser Ala Leu Ser Leu Leu Gln His Ser Asp
                  65                  70                  75

 Leu His Pro Leu Arg Gly Phe His Cys Pro Arg Gly Glu Asn Ala
                  80                  85                  90

 Pro Gly Ser Val Thr
                  95

<210> 4281
<211> 4102
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2273-2546
<223> Unknown base

<400> 4281
 cgcacctgca cccggcggag ccggaggagg gcgacagcaa cgtggcgcgg 50

 actacgccgc ctcccgggcg cccccctgcg cccagctccg aggaggagga 100

 cggagaggca gtggcacact gatgggcgag ctgagcgcag agctgcgaag 150

 ggggaactgt ttgcagtagc agccgctgct ccctttctcc ctctcttcct 200

 ccctcttttg ccactgtctg ggccccatct gggattcctg ggccctttgg 250

 aaaagagttg gtgaaatgcg cagccggctg tggacggggg aggaggaagg 300

 ggacagaggg agcaggtagg aaacacttta gttgggggtg gggggcgtct 350

 ccctctggcc ccctgtctgt cttcctctcc gcggtggagc aaactgtgga 400

 cttgcctggc acttaaacct tggtagatct gggtttataa tcggccattc 450

 ttaagcacgt ggggttgggg gaaagttcgg agtacccatt cctgccgttg 500

 cttcctatcc tgggcttgga agaatcctgg tagaaaggcc agagtgggtt 550

 tgtggagtcg ccactgcggg accagcacga aagctgcttg tctgctttgg 600

 cggagctgag ctgtgtatgg gatccaggag gctggggtga tttattttat 650

 gggattcctg gagcgcaggg ctggtgaatc catgacaagg tccgggagca 700

 gcagaccaaa accacagcag cctcctatta agtgtaacaa atagttaagc 750

 aaactcgggc tacaaacaaa gactttgcta cctccctcct ccacaacccc 800

 caagtaatta gccttctgga gctggctctt agctgaggct cctgctacct 850

 cctgctccac ccgccccttc ctaggttaca agtaaatcat tgtcaagggc 900

 cagccagggg aaggtttcaa ttaaggttct gttctgctgc ctttgtttct 950

 cccctgctgt tgtaggcact tacagctgcg ttgttatgaa aggagggaat 1000

 agccctttgt gtctttgatc taattaaacc tgcttggctg tgtttatccg 1050

 cagggcaggt cacagatagg gttggctgtg ccactccata aagtatctat 1100

 tgtggaagca gccaaaaagg gctgctgtgg caggaattgg ttaatttctc 1150

 cttccacttc ccttcctgaa tagtgaaggg agccctttta aaacaaggct 1200

 ttggtggtaa tcctgtgatt tttttttctc ccccatcccc tcactggccc 1250

 atccctctca ccctcacttt tgttctgctg gtgggtaaaa tcttaggctg 1300

 aacacatatt tcaatggtaa gatacttatt ttgctatcca cacttgatgc 1350

 aattgaattc aaggtgcaaa gtcttgtact gaagcagtct ccttgttgct 1400

 tggagaacac ctccttcaga gccctttgtt aaataagagg ggcgacgttg 1450

 atcatagatg ccacctggtt agcaccgaat ctgactttgg tgacagtcct 1500

 aaagcacagt tggtgattgt gagatctgtt agcggcaggc tgagcagata 1550

 ctacttggtt ttgcttggta tgagatacta ctgtttgctt agtatgagat 1600

 tttttccagc ctgtctctta aactcctgtg acatcttcaa tgatatgtgc 1650

 cctcagttgc agcatagctt ctctgctgcc tattgccatt gctgtctcaa 1700

 aagttgagtg aattttgagg cgtctttttt ttttttcctc tcttgggagt 1750

 cgttgtaaac tactgtgtac aagtcatttt gtgatatgat tctgaacagt 1800

 tggaatagaa tcatagttaa gtggtacagc catggctatc gtcaggcctg 1850

 ttgcctggag atctctaagt taaggcaaca agacttaaag aattttctaa 1900

 tacacttgtt tcacacatgg acgttgaggc catagtcttt aaaagcttgg 1950

 acctttgtag cacctcaaca tgaaagggca ttagctatgt ttcctgtttt 2000

 tacagtgatc accaaacaga tcttgccact ttgattgtta aaaatgaacc 2050

 acattctagc cctggtctgg gactttggag ggagatgaat ttcttgttgg 2100

 aaatgtaaat ctagtgtcca tatttaatac tctcacagct ttgtgtttat 2150

 tctctttgct catggaatag cagaacaaga taaacatggg ttaagacatt 2200

 taggagaacc tgctgtatct aacccagttg gattttcttt catgcttaac 2250

 acagtagtga aaatagaacg tannnnnnnn nnnnnnnnnn nnnnnnnnnn 2300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnacag 2550

 tagtaataac caccgtgtag acaagtggga gggaagaata gaatggcact 2600

 gtccagctct gggctagcca gatcaactcc cccacccgtc ttcttcctct 2650

 gtcccagaat ggaaaatgat gtatggtcag tcacgctgaa gtatagcagc 2700

 gactgtgtta agagagagca gtgactctct cttctagaga agaggttttc 2750

 aataacaggg cttggaaatg aactagaata ggaaatagat cttttcagat 2800

 gctgctttcc catgtaatac aagcgtttct acagggtacc agaggtgtga 2850

 aatatgtgac acttaagaac agtgattttt attgggaatt ttcttagggt 2900

 tattacactt aaagcaacaa ccaactagta acagctccag gaaaggggaa 2950

 tgaatcaact cttggttctt tcctgaagac ggcagtgttg tggataagtg 3000

 agtttttaat gccctggcag tggctacatt tgacacttta gaaaaaataa 3050

 acatatttaa taatttttgt ttctccttag gaataagact gtagaactgt 3100

 tttgtactgt gaattacgga tgctctttga aggaaagaaa tatcgattct 3150

 aatgttcttc agaagttctg gcagggataa gcaggacatc gactggaacg 3200

 tatgctaaat gaaagcagac aaatttctat tttcttacct gagcaaatat 3250

 tttattgaaa ctgcttatgt atgtcaaagg agcccacaac ttcagctaca 3300

 caactttttg tattgaaaga actcatactt tttgtagctt ttatttcaca 3350

 tttaatttaa agtgactttt agcactaaaa tgcctagaag attttactcc 3400

 agacctataa ggaaatgttt agtttttatg aaaaatgaca agtcgatggt 3450

 taaacttctc atgtctttgg tgctttggcc ctaatagcac tggacaacac 3500

 cacgaccaca tggaaacata tttttggaag caaaacttta attttatata 3550

 acgtatgcta tggagagcta agacaattta aggactactt gttttctatt 3600

 ttttttctta ataaaatgga atccactgtg ttgaagactc ttgatatcat 3650

 gtgcttgtct aaccattttt tgttttataa attagaataa aatatagttg 3700

 tgataatggt catcgaatgg atttgtttgg aaagctacat cttatttgtg 3750

 aaatgttttt taaatcagag taactatcaa ctgattcagc tttttgttgt 3800

 tttgttcttg gctataatac ttgtgactca tgaagaatta tgttgacaaa 3850

 caggataaat tccacatgca ttttatttcc cagtgagttg tataaacttt 3900

 atttttgttg aaggttgtat gttaaatcaa tgttacattc ttatatcact 3950

 tcttgagaag gaagttccga tttgaaattg tatcatttcc ttcaaaatga 4000

 agggcagtgc ttagttaaat aaaagattga tgatatcttt taagccattt 4050

 cctcttcact atgtcttatt aaaataaaac ctgtcaagtt cttttcaaaa 4100

 ga 4102

<210> 4282
<211> 1078
<212> DNA
<213> Homo sapien

<400> 4282
 gttgcaggta gcggtagcga tggacactct ggatcgagta gtaaagccca 50

 aaacgaaaag agccaagaga ttccttgaga agagagaacc gaaactcaat 100

 gaaaatatta aaaatgccat gctgattaaa gggggaaatg caaatgcaac 150

 agtgacaaaa gtacttaaag atgtgtatgc actgaaaaaa ccatacggtg 200

 tactatataa aaagaaaaat attacaagac cttttgagga tcagacatca 250

 ctggaattct tttcaaagaa gtcagattgt tctttattca tgtttggctc 300

 ccataataag aagcggccaa ataatctagt aataggtcgt atgtatgact 350

 accatgtgct ggatatgatt gaattaggta ttgagaattt tgtctctcta 400

 aaagacatta agaacagtaa atgtcctgag ggaacaaaac ccatgctgat 450

 atttgctggc gatgatttcg atgtaacaga agattataga agactaaaaa 500

 gtcttcttat tgatttcttc agaggcccca cagtatcaaa tatccgcctg 550

 gctggattag agtatgttct gcacttcact gcactgaatg ggaagattta 600

 ctttcgaagc tataagttgc tgttgaagaa atctggttgc agaacaccac 650

 ggattgaatt ggaagagatg ggaccctcat tggatctggt tctgaggagg 700

 acacacctgg catcggatga cctttataaa ttatctatga aaatgccaaa 750

 agctctcaag ccaaagaaga agaaaaatat ttcccatgat acttttggta 800

 caacttatgg aaggattcat atgcagaagc aagacctaag caaactacaa 850

 accaggaaaa tgaaggggtt gaagaagcga cctgcagaaa ggataacaga 900

 agaccacgag aaaaagtcaa aaagaattaa aaaaaattga tggaacttaa 950

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1000

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1050

 aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1078

<210> 4283
<211> 306
<212> PRT
<213> Homo sapien

<400> 4283
 Met Asp Thr Leu Asp Arg Val Val Lys Pro Lys Thr Lys Arg Ala
   1               5                  10                  15

 Lys Arg Phe Leu Glu Lys Arg Glu Pro Lys Leu Asn Glu Asn Ile
                  20                  25                  30

 Lys Asn Ala Met Leu Ile Lys Gly Gly Asn Ala Asn Ala Thr Val
                  35                  40                  45

 Thr Lys Val Leu Lys Asp Val Tyr Ala Leu Lys Lys Pro Tyr Gly
                  50                  55                  60

 Val Leu Tyr Lys Lys Lys Asn Ile Thr Arg Pro Phe Glu Asp Gln
                  65                  70                  75

 Thr Ser Leu Glu Phe Phe Ser Lys Lys Ser Asp Cys Ser Leu Phe
                  80                  85                  90

 Met Phe Gly Ser His Asn Lys Lys Arg Pro Asn Asn Leu Val Ile
                  95                 100                 105

 Gly Arg Met Tyr Asp Tyr His Val Leu Asp Met Ile Glu Leu Gly
                 110                 115                 120

 Ile Glu Asn Phe Val Ser Leu Lys Asp Ile Lys Asn Ser Lys Cys
                 125                 130                 135

 Pro Glu Gly Thr Lys Pro Met Leu Ile Phe Ala Gly Asp Asp Phe
                 140                 145                 150

 Asp Val Thr Glu Asp Tyr Arg Arg Leu Lys Ser Leu Leu Ile Asp
                 155                 160                 165

 Phe Phe Arg Gly Pro Thr Val Ser Asn Ile Arg Leu Ala Gly Leu
                 170                 175                 180

 Glu Tyr Val Leu His Phe Thr Ala Leu Asn Gly Lys Ile Tyr Phe
                 185                 190                 195

 Arg Ser Tyr Lys Leu Leu Leu Lys Lys Ser Gly Cys Arg Thr Pro
                 200                 205                 210

 Arg Ile Glu Leu Glu Glu Met Gly Pro Ser Leu Asp Leu Val Leu
                 215                 220                 225

 Arg Arg Thr His Leu Ala Ser Asp Asp Leu Tyr Lys Leu Ser Met
                 230                 235                 240

 Lys Met Pro Lys Ala Leu Lys Pro Lys Lys Lys Lys Asn Ile Ser
                 245                 250                 255

 His Asp Thr Phe Gly Thr Thr Tyr Gly Arg Ile His Met Gln Lys
                 260                 265                 270

 Gln Asp Leu Ser Lys Leu Gln Thr Arg Lys Met Lys Gly Leu Lys
                 275                 280                 285

 Lys Arg Pro Ala Glu Arg Ile Thr Glu Asp His Glu Lys Lys Ser
                 290                 295                 300

 Lys Arg Ile Lys Lys Asn
                 305

<210> 4284
<211> 5095
<212> DNA
<213> Homo sapien

<400> 4284
 acttgggcgc gactggcttt attgtaggtc cccatgagct ggtgggggct 50

 gtaggggtaa ccaggcaggg cgtctggcgc tgttggggct gcgtttttcc 100

 ggagtccccc tatgcgaggc cgtgcccctc ttcgcccggc tcctggtgct 150

 ccccagccgc cggcccgctc ccggaagctg cagcagctgg taacaaagag 200

 cctgccgggc cgcctgctgc cggggccgag gtatccagga gtcgggcgga 250

 gcggctgggg atgagcgcga gccggaccat gcgtccgggt tcgcggcggt 300

 gagggtcgcg gccggcggcc gaggcgcagg tgcgggtcga gagaccggcg 350

 cctccctccc cgccgcccgt ggactctgag cgcaggtgtt tctactctgc 400

 cggccgctcc acctgggaaa gcgccttcaa gagctacctc tggcggcacc 450

 tggccctcag ctgcagggaa accgcactca aacctgccgc cgagcccggg 500

 tttttctgca aaactcagag gacctggctc ttgcccgagg tgccctgaac 550

 cattgtgtga ataagctggg gaagcctgac tggagtgttt tttcttttta 600

 ataaaaagag tttttctgaa tctcaatttt tagaaatttt ttttgcgaag 650

 tttgcaatac tctctacctc ttcgcatcct ctcttgctcg tggagtcttt 700

 ttcctcctca gctataaata ttttttacta tcggcggagc agaccaggga 750

 tgaacgtctt ttaattgcaa gtataactgt taaaaccacg tcgggatagt 800

 agtcaagatg gataaaaagt cctttgaaat ggtgctggat gaaattagaa 850

 aggtggttga tttgctgaga tatttttcct gggccgagcc ccagttgaag 900

 gcaatgaaag cattacagca taaaatggtg gctgtccagc caacagaagt 950

 ggtcaatata ctcaactgtt tcactttcag taaagacaaa ctagttgctc 1000

 ttgaactgtt agcctcgaac attattgatg cacagaattc tcgtcctatt 1050

 gaagatttat tcagggtaaa tatgtctgag aagaaacggt gcaagagaat 1100

 acttgaacag ctttcaaggg gggctgcaaa gctcctcatg ctatgatatc 1150

 ttcttgtgga acaatcccag gaaatccata tcccaaagga agacctagcc 1200

 gcataaatgg aattttccca ggaactcctt tgaaaaaaga tggtgaagaa 1250

 tgtactaacg aaggcaaagg aatagctgca cgaattcttg ggccatccaa 1300

 accacctcct tcaacatata atccacataa acctgttcct tatccgatac 1350

 ctccatgccg accacatgca actattgcac caagtgctta taacaatgca 1400

 ggtctggtac cattagcgaa tgtcatagct ccacctccac ctccatatac 1450

 tcctaatcct gtaggaacag agaatgaaga cctttcgaat ccgtcaaaac 1500

 ctatacagaa tcaaacattt tccaccccag caagtcaact cttttctcct 1550

 catggttcta atccttcaac acctgctgca actcctgttc ctactgcatc 1600

 cccagtcaag gcaattaatc atccatcagc atcagcagct gccaccgttt 1650

 ctggaatgaa cctgctgaat actgtccttc ctgtgttccc agggcaggtc 1700

 tcctcagccg ttcacacacc tcagccatca ataccaaacc caacagttat 1750

 cagaacccct tcattgccca ctgcacctgt tacatccatc cacagtacaa 1800

 ccaccactcc tgttccttcc attttttctg gcctagtgtc actgccaggt 1850

 ccttctgcca ctcctaccgc agccactcct accccaggac ctacaccacg 1900

 gtccactctt ggttccagtg aagcatttgc ttctacttct gcacctttca 1950

 ctagcctccc cttttccacc agctcttctg ctgcttctac cagcaaccca 2000

 aattctgctt cattgtcatc agtttttgca gggctccctt tgcccttacc 2050

 accaacatcc caaggcctat ccaacccgac tcctgtaatt gctggtggct 2100

 ctactcccag cgttgccggt ccacttggtg tgaacagtcc tcttttgtct 2150

 gcgttaaaag gttttctgac atccaatgac accaatttaa tcaactcctc 2200

 tgctttatcc tctgctgtca caagtgggct ggcttcacta tcttctctta 2250

 ctcttcagaa ctctgactct tctgcttcag cccctaacaa gtgctatgcc 2300

 ccatcagcca tccctacccc acagaggact tccactccag ggttggccct 2350

 gttcccaggc ctgccgtctc ccgtggctaa ctcaacttcc actcccctga 2400

 cattgcctgt acagtctcct ttagccactg ctgcatcagc ttccacgtca 2450

 gtgccagtta gctgtggctc ctcagcctcc cttttgcgtg gcccccaccc 2500

 aggtacctca gatctgcata tttcatctac ccctgctgca acaactcttc 2550

 ctgttatgat caaaactgag cccacaagtc ctactccctc ggccttcaaa 2600

 ggtccatctc attctgggaa tccctctcat ggcactttag gtttgtcagg 2650

 gacattgggc cgtgcatata cttcaacatc cgtgcccatc agtttatctg 2700

 cttgccttaa tcctgcattg tcaggtctct ccagcttgag tactccttta 2750

 aatggttcaa atcctctttc ctctatttcc cttccaccac atggttcctc 2800

 cactcccatt gcaccagtat tcactgctct tccttctttt acttctttga 2850

 ccaacaattt tcctttaact ggcaacccat ctcttaatcc gtcagtatct 2900

 ctcccagggt cattaatagc cacctcatct accgctgcca cctccacatc 2950

 tctccctcat cctagctcaa cggcagctgt tctctcaggg ctttctgctt 3000

 cagcaccagt ctcagcagca cctttccccc tcaacctgtc cactgctgtt 3050

 ccctcacttt tctctgttac tcaaggacct ctgtcatctt caaatccctc 3100

 ctatccaggc ttttctgtct ctaatacccc aagcgttacc cctgctcttc 3150

 cctcattccc ggggctgcag gcgccctcta cagtcgcagc tgtcacacca 3200

 ctacctgtgg ctgccacagc cccatcccca gctccagtcc tcccaggatt 3250

 cgcctcagca ttcagttcca atttcaactc cgctcttgtt gcacaagccg 3300

 gtttatcatc tggacttcaa gctgcaggca gttctgtttt tccaggcctt 3350

 ttgtccctcc cgggtatccc tgggtttcct cagaatcctt cacaatcatc 3400

 cttgcaagaa ttacagcata atgcggctgc gcagtcagca ttgttacagc 3450

 aggtccattc agcttcggct ctggaaagct atccagctca gcctgatggg 3500

 tttcctagtt atccttcagc gccaggaaca ccattttctt tgcaaccaag 3550

 cctgtcccag agtgggtggc agtgaatact tttaactttt attctccttc 3600

 agagcaacat cagaattgcc tgagaactgc aatgaacaat ctgacaaatg 3650

 tgaagctggc caaaagtcgg aaaatgagaa tgagggtaat cctggagaaa 3700

 ttgtgacaac aatttgaaaa ttgtggttgc attttaaagt gtgaacactc 3750

 ccctatgtaa atatgctgac aataaattgt atggagaatg gtatttaaaa 3800

 agtgtttgga gacttttcac ctgtcctata aaattttgaa ttgtgtatgt 3850

 gatctacata gaaagaatat taaagagtag gttgaactct ttatagccga 3900

 atacagcctt aaatatgctt gtatagcatc cactggcaga agtaatagtt 3950

 gtgcctcaga cttgggggtt gcatgtggcc ctgggggagt tactaccctt 4000

 ggtatgcatg agcggttcct attagcatca gtgggaactc agtactctgt 4050

 atgtatccac aaaagggaac ttgagaccca cagttattct taatttctga 4100

 tattaacaac cgtacatact gctgaattta actcaaaata tttcaggtaa 4150

 gtgaaagtgg tgcttaatgt agactataga atgactttca ggtgttttca 4200

 actgaaagta tatatccaga actgcatcct tatagaaata caagtaagac 4250

 ttaggataat ttgccttcaa aacagttttc ctaatctcag cagtatccag 4300

 tgagtgaaga acacttgact gactcttggg ccacctctgt tacttactgt 4350

 actatggaag ctcctggtga atgtttacaa ttatgggatg tagtatttct 4400

 atttgtactt taagtcaaat gcttatatga aatatgtgac aacaaataga 4450

 gaagactggc tctgttagta attatgcagt atgtactcta tttaaggatc 4500

 tgtggtagta taacatgagt gaatgtcatt aattttgaag taataactgc 4550

 cacatgtggg aagtagggga gtaaggagaa tgaattccaa tctgtgatta 4600

 aaagtgtaaa ctatagactc tactgtagta catttcagga tctagaagtt 4650

 ttacttttat aaagatggtg tccggaagat gttgctaatg tattttactt 4700

 caacataggg aacaaacttt ttaagtatat taataaacct gtatggttag 4750

 tttttaacag ttttttaaaa taaactatgg atatgacaaa tattctgtgt 4800

 tttactaagt gcttggatag gctttctaat tttgtatacg tgctagagtt 4850

 aattattgaa catttttatc caaatttagt tgtaactctg tttatactac 4900

 tgattgctca ttcgtttaaa tgatatttta atgtaaaagt cataaccaac 4950

 atatgaacag acagatttat gtctttaaac acagaatgta agctatagtt 5000

 taatctgata ccagttgctg gaagttgcca tttgtttttc ttaaatctat 5050

 acccataaaa cttcttttaa gattaaaaaa aaaaaaaaaa aaaaa 5095

<210> 4285
<211> 810
<212> PRT
<213> Homo sapien

<400> 4285
 Met Ile Ser Ser Cys Gly Thr Ile Pro Gly Asn Pro Tyr Pro Lys
   1               5                  10                  15

 Gly Arg Pro Ser Arg Ile Asn Gly Ile Phe Pro Gly Thr Pro Leu
                  20                  25                  30

 Lys Lys Asp Gly Glu Glu Cys Thr Asn Glu Gly Lys Gly Ile Ala
                  35                  40                  45

 Ala Arg Ile Leu Gly Pro Ser Lys Pro Pro Pro Ser Thr Tyr Asn
                  50                  55                  60

 Pro His Lys Pro Val Pro Tyr Pro Ile Pro Pro Cys Arg Pro His
                  65                  70                  75

 Ala Thr Ile Ala Pro Ser Ala Tyr Asn Asn Ala Gly Leu Val Pro
                  80                  85                  90

 Leu Ala Asn Val Ile Ala Pro Pro Pro Pro Pro Tyr Thr Pro Asn
                  95                 100                 105

 Pro Val Gly Thr Glu Asn Glu Asp Leu Ser Asn Pro Ser Lys Pro
                 110                 115                 120

 Ile Gln Asn Gln Thr Phe Ser Thr Pro Ala Ser Gln Leu Phe Ser
                 125                 130                 135

 Pro His Gly Ser Asn Pro Ser Thr Pro Ala Ala Thr Pro Val Pro
                 140                 145                 150

 Thr Ala Ser Pro Val Lys Ala Ile Asn His Pro Ser Ala Ser Ala
                 155                 160                 165

 Ala Ala Thr Val Ser Gly Met Asn Leu Leu Asn Thr Val Leu Pro
                 170                 175                 180

 Val Phe Pro Gly Gln Val Ser Ser Ala Val His Thr Pro Gln Pro
                 185                 190                 195

 Ser Ile Pro Asn Pro Thr Val Ile Arg Thr Pro Ser Leu Pro Thr
                 200                 205                 210

 Ala Pro Val Thr Ser Ile His Ser Thr Thr Thr Thr Pro Val Pro
                 215                 220                 225

 Ser Ile Phe Ser Gly Leu Val Ser Leu Pro Gly Pro Ser Ala Thr
                 230                 235                 240

 Pro Thr Ala Ala Thr Pro Thr Pro Gly Pro Thr Pro Arg Ser Thr
                 245                 250                 255

 Leu Gly Ser Ser Glu Ala Phe Ala Ser Thr Ser Ala Pro Phe Thr
                 260                 265                 270

 Ser Leu Pro Phe Ser Thr Ser Ser Ser Ala Ala Ser Thr Ser Asn
                 275                 280                 285

 Pro Asn Ser Ala Ser Leu Ser Ser Val Phe Ala Gly Leu Pro Leu
                 290                 295                 300

 Pro Leu Pro Pro Thr Ser Gln Gly Leu Ser Asn Pro Thr Pro Val
                 305                 310                 315

 Ile Ala Gly Gly Ser Thr Pro Ser Val Ala Gly Pro Leu Gly Val
                 320                 325                 330

 Asn Ser Pro Leu Leu Ser Ala Leu Lys Gly Phe Leu Thr Ser Asn
                 335                 340                 345

 Asp Thr Asn Leu Ile Asn Ser Ser Ala Leu Ser Ser Ala Val Thr
                 350                 355                 360

 Ser Gly Leu Ala Ser Leu Ser Ser Leu Thr Leu Gln Asn Ser Asp
                 365                 370                 375

 Ser Ser Ala Ser Ala Pro Asn Lys Cys Tyr Ala Pro Ser Ala Ile
                 380                 385                 390

 Pro Thr Pro Gln Arg Thr Ser Thr Pro Gly Leu Ala Leu Phe Pro
                 395                 400                 405

 Gly Leu Pro Ser Pro Val Ala Asn Ser Thr Ser Thr Pro Leu Thr
                 410                 415                 420

 Leu Pro Val Gln Ser Pro Leu Ala Thr Ala Ala Ser Ala Ser Thr
                 425                 430                 435

 Ser Val Pro Val Ser Cys Gly Ser Ser Ala Ser Leu Leu Arg Gly
                 440                 445                 450

 Pro His Pro Gly Thr Ser Asp Leu His Ile Ser Ser Thr Pro Ala
                 455                 460                 465

 Ala Thr Thr Leu Pro Val Met Ile Lys Thr Glu Pro Thr Ser Pro
                 470                 475                 480

 Thr Pro Ser Ala Phe Lys Gly Pro Ser His Ser Gly Asn Pro Ser
                 485                 490                 495

 His Gly Thr Leu Gly Leu Ser Gly Thr Leu Gly Arg Ala Tyr Thr
                 500                 505                 510

 Ser Thr Ser Val Pro Ile Ser Leu Ser Ala Cys Leu Asn Pro Ala
                 515                 520                 525

 Leu Ser Gly Leu Ser Ser Leu Ser Thr Pro Leu Asn Gly Ser Asn
                 530                 535                 540

 Pro Leu Ser Ser Ile Ser Leu Pro Pro His Gly Ser Ser Thr Pro
                 545                 550                 555

 Ile Ala Pro Val Phe Thr Ala Leu Pro Ser Phe Thr Ser Leu Thr
                 560                 565                 570

 Asn Asn Phe Pro Leu Thr Gly Asn Pro Ser Leu Asn Pro Ser Val
                 575                 580                 585

 Ser Leu Pro Gly Ser Leu Ile Ala Thr Ser Ser Thr Ala Ala Thr
                 590                 595                 600

 Ser Thr Ser Leu Pro His Pro Ser Ser Thr Ala Ala Val Leu Ser
                 605                 610                 615

 Gly Leu Ser Ala Ser Ala Pro Val Ser Ala Ala Pro Phe Pro Leu
                 620                 625                 630

 Asn Leu Ser Thr Ala Val Pro Ser Leu Phe Ser Val Thr Gln Gly
                 635                 640                 645

 Pro Leu Ser Ser Ser Asn Pro Ser Tyr Pro Gly Phe Ser Val Ser
                 650                 655                 660

 Asn Thr Pro Ser Val Thr Pro Ala Leu Pro Ser Phe Pro Gly Leu
                 665                 670                 675

 Gln Ala Pro Ser Thr Val Ala Ala Val Thr Pro Leu Pro Val Ala
                 680                 685                 690

 Ala Thr Ala Pro Ser Pro Ala Pro Val Leu Pro Gly Phe Ala Ser
                 695                 700                 705

 Ala Phe Ser Ser Asn Phe Asn Ser Ala Leu Val Ala Gln Ala Gly
                 710                 715                 720

 Leu Ser Ser Gly Leu Gln Ala Ala Gly Ser Ser Val Phe Pro Gly
                 725                 730                 735

 Leu Leu Ser Leu Pro Gly Ile Pro Gly Phe Pro Gln Asn Pro Ser
                 740                 745                 750

 Gln Ser Ser Leu Gln Glu Leu Gln His Asn Ala Ala Ala Gln Ser
                 755                 760                 765

 Ala Leu Leu Gln Gln Val His Ser Ala Ser Ala Leu Glu Ser Tyr
                 770                 775                 780

 Pro Ala Gln Pro Asp Gly Phe Pro Ser Tyr Pro Ser Ala Pro Gly
                 785                 790                 795

 Thr Pro Phe Ser Leu Gln Pro Ser Leu Ser Gln Ser Gly Trp Gln
                 800                 805                 810

<210> 4286
<211> 1146
<212> DNA
<213> Homo sapien

<400> 4286
 gtgcgtacgt gcgtcgtctc tatggtggcg gcggatttgg agggacccta 50

 cgaaccagga gtcaggcgag ccgatctggg gctgcaggat gttccgctgg 100

 gagcgctcca ttcccctgcg aggctcggcc gccgccctgt gcaacaacct 150

 cagtgtgctg cagctgccgg ctcgcaacct cacgtatttt ggcgtggttc 200

 atggaccaag cgcccagctt ctcagcgctg ctcctgaggg tgtgcccttg 250

 gcccagcgcc agctccacgc taaggagggt gctggagtga gtcccccact 300

 tatcactcag gtccactggt gtgtcctccc cttccgagtg ctgctggtac 350

 tcacctcaca tcgaggaata cagatgtacg agtccaatgg ctacaccatg 400

 gtctactggc atgcactgga ctctggagat gcctccccag tacaggctgt 450

 gtttgcccgg ggaattgctg ccagtggcca cttcatctgt gtgggaacgt 500

 ggtcaggccg ggtgctggtg tttgacatcc cagcaaaggg tcccaacatt 550

 gtactgagcg aggagctggc tgggcaccag atgccaatca cagacattgc 600

 caccgagcct gcccagggac aggattgtgt ggctgacatg gtgacggcag 650

 atgactcagg cttgctgtgt gtctggcggt cagggccaga attcacatta 700

 ttgacccgca ttccaggatt tggagttccg tgcccctctg tgcagctgtg 750

 gcaggggatc atagcagcag gctatgggaa cggacaagtg catctatatg 800

 aggccactac aggaaatcta catgtccaga tcaatgccca tgcccgggcc 850

 atctgcgccc tggacctggc ttctgaggtg ggcaagctac tctctgcagg 900

 tgaggacacc tttgtgcata tctggaagct gagcagaaac ccagagagtg 950

 gctacattga ggtggaacac tgtcatggtg agtgtgtcgc cgacacccag 1000

 ctgtgtggtg ctcgattttg tgattcctca ggcaactcct ttgctgtgac 1050

 tggctatgac cttgcggaga tccggagatt cagcagtgtg tgagaagagc 1100

 agccttcctt tgtccctgtg gtattcataa agtacccgct ccaccc 1146

<210> 4287
<211> 334
<212> PRT
<213> Homo sapien

<400> 4287
 Met Phe Arg Trp Glu Arg Ser Ile Pro Leu Arg Gly Ser Ala Ala
   1               5                  10                  15

 Ala Leu Cys Asn Asn Leu Ser Val Leu Gln Leu Pro Ala Arg Asn
                  20                  25                  30

 Leu Thr Tyr Phe Gly Val Val His Gly Pro Ser Ala Gln Leu Leu
                  35                  40                  45

 Ser Ala Ala Pro Glu Gly Val Pro Leu Ala Gln Arg Gln Leu His
                  50                  55                  60

 Ala Lys Glu Gly Ala Gly Val Ser Pro Pro Leu Ile Thr Gln Val
                  65                  70                  75

 His Trp Cys Val Leu Pro Phe Arg Val Leu Leu Val Leu Thr Ser
                  80                  85                  90

 His Arg Gly Ile Gln Met Tyr Glu Ser Asn Gly Tyr Thr Met Val
                  95                 100                 105

 Tyr Trp His Ala Leu Asp Ser Gly Asp Ala Ser Pro Val Gln Ala
                 110                 115                 120

 Val Phe Ala Arg Gly Ile Ala Ala Ser Gly His Phe Ile Cys Val
                 125                 130                 135

 Gly Thr Trp Ser Gly Arg Val Leu Val Phe Asp Ile Pro Ala Lys
                 140                 145                 150

 Gly Pro Asn Ile Val Leu Ser Glu Glu Leu Ala Gly His Gln Met
                 155                 160                 165

 Pro Ile Thr Asp Ile Ala Thr Glu Pro Ala Gln Gly Gln Asp Cys
                 170                 175                 180

 Val Ala Asp Met Val Thr Ala Asp Asp Ser Gly Leu Leu Cys Val
                 185                 190                 195

 Trp Arg Ser Gly Pro Glu Phe Thr Leu Leu Thr Arg Ile Pro Gly
                 200                 205                 210

 Phe Gly Val Pro Cys Pro Ser Val Gln Leu Trp Gln Gly Ile Ile
                 215                 220                 225

 Ala Ala Gly Tyr Gly Asn Gly Gln Val His Leu Tyr Glu Ala Thr
                 230                 235                 240

 Thr Gly Asn Leu His Val Gln Ile Asn Ala His Ala Arg Ala Ile
                 245                 250                 255

 Cys Ala Leu Asp Leu Ala Ser Glu Val Gly Lys Leu Leu Ser Ala
                 260                 265                 270

 Gly Glu Asp Thr Phe Val His Ile Trp Lys Leu Ser Arg Asn Pro
                 275                 280                 285

 Glu Ser Gly Tyr Ile Glu Val Glu His Cys His Gly Glu Cys Val
                 290                 295                 300

 Ala Asp Thr Gln Leu Cys Gly Ala Arg Phe Cys Asp Ser Ser Gly
                 305                 310                 315

 Asn Ser Phe Ala Val Thr Gly Tyr Asp Leu Ala Glu Ile Arg Arg
                 320                 325                 330

 Phe Ser Ser Val


<210> 4288
<211> 5587
<212> DNA
<213> Homo sapien

<400> 4288
 caacaacaaa aggacttgga ctggccggcc tgggcgcacg acccgagggc 50

 tggagtcggc cccgcgcctg ccgtctgggt acctgaacga ggtgcagcgc 100

 agccggcccc accgcagcta cctcagcagt cccgccccgc ccgcgtcctt 150

 ccccgccgag ccggcctcgc tcccttcccc gcgcaccccg cacggcccgg 200

 gcccacgtac aatgactctt cttgcttttc acctaagttg aataagcacc 250

 ctgtgcactt taatctcctg tcggtaccat tgggccaact aaagacaagg 300

 ttttgaaatc tcagctataa aagacatcca gccaaactct cagtcttgcc 350

 ttaacaatgt tccagaggct gaataaaatg tttgtgggtg aagtcagttc 400

 ttcctccaac caagaaccag aattcaatga gaaagaagat gatgaatgga 450

 ttcttgttga cttcatagat acttgcactg gtttctcagc agaagaagaa 500

 gaagaagagg aggacatcag tgaagagtca cctactgagc acccttcagt 550

 cttttcctgt ttaccggcat ctcttgagtg cttggctgat acaagtgatt 600

 cctgctttct ccagtttgag tcatgtccaa tggaggagag ctggtttatc 650

 accccacccc catgttttac tgcaggtgga ttaaccacta tcaaggtgga 700

 aacaagtcct atggaaaacc ttctcattga acatcccagc atgtctgtct 750

 atgctgtgca taactcctgc cctggtctca gtgaggccac ccgtgggact 800

 gatgaattac atagcccaag tagtcccaga gtggaagctc aaaatgaaat 850

 ggggcagcat attcattgtt atgttgcagc tcttgctgct catacaactt 900

 ttctggaaca acccaagagc tttcgccctt cccagtggat aaaagaacac 950

 agtgaaagac agcctcttaa cagaaatagc cttcgtcgcc aaaatcttac 1000

 cagggattgc caccctcggc aagtcaagca caatggctgg gttgttcatc 1050

 agccctgccc gcgtcagtac aattactaat agtttcaagt tttgttggtt 1100

 ggtttctctt ggtttgtgct tacatgtatg gatgtgtgta tatgtacagt 1150

 gaaaatgttg tctctttaca accaattgat aaccaatcac atagttttat 1200

 cagtgtattt agacactatc ttgaaaatca gatttatatg ctgtgtatca 1250

 cataatgcct tgcctttaac atttactttt tttgtacact ttttcagatt 1300

 atttctggaa acatatcaat ataattacag tgtttggggg tgtctttaaa 1350

 tatattaggt tatacattag tcagcatttt aaagacattt cttcccaagt 1400

 acgagaatag gcatctttca ttttcatttt attttgtatt acttaatctt 1450

 ttaagcaagc aaaaatttat tctcagggtc agctgtacac tttattgacc 1500

 agtacttgat aatctctctg tatatgatga atacattttt acacactaac 1550

 attagcatta acaggtgata gttgccatgg atataatgga attatggctg 1600

 gactttcttt tgaaagaaaa cttgatgtat tctgtgtgta tggtttttcc 1650

 ccagattagt catacagttc atttggaatt caggtacatt aagctttagt 1700

 gaagagtgca tgcagtaatt ccaatgtgac tgcatgacgt ggtacagaca 1750

 ttacaggtgt tgtagacaga ggcacttgtc tcgtgcagag ggattaaatt 1800

 agacctgtga gattatattt ggaaaaattc atgtctgtaa ctaacccatt 1850

 agtgcagtat ttaatttgtt actattcctt cccgccaatt ctgtccactc 1900

 ctcacctcgc atcagctata aatttggaag tacttgtcca ggcactcaag 1950

 tgacttcata tttctctctg cccatgggaa aagagatagg ctttatattt 2000

 ccacagagtg aaaaatcctc tgtcatggag cctgtcctgc caagtggcaa 2050

 gagtgtgggg actgtctggt gatgatgtct ttcatggcat ctgagtgaag 2100

 agtgacaggt tggctcaact tttttctttt ttttttttta attgccttgt 2150

 attgtaagta ttcttccctg cagtccaagt gacttttcat tttttgtttt 2200

 aacttcaggc aaaatcttta accactctgg cctctgtttc ccccaccaac 2250

 ggggagcagt gacatttacc tccctcacag agtcactgtg aggattctat 2300

 actgatttga agtggagctg ttcagaactg aaccttgtag gaaattccaa 2350

 gggcctttct actgaatctg gtgatggggt ggggccgtgg cactttctct 2400

 gccacagctg ttcttcacag tgttggtgct aatgaggcca gggtgcaggg 2450

 ttcgattcac acgtaggcca gttaacttag agaaaatcta tttccttacc 2500

 tctagccagt cacttccttt ttccgcagtt gtgatgggtt ttgctgagcc 2550

 atccactctg actgatttcc tctgaagtaa acatatttac aatccaaagc 2600

 aattctactg acagaagtgt tgccttcata atcaaacagc ttgtttttcc 2650

 atctcctctg caaccctaat taaatgagta caggtctaca aaatgttttc 2700

 aaggagaaaa gcagcatatc cttaagtgaa gtattatatt tttcaataac 2750

 cctgtagtgg cttgatgcag ggaaccctgg gggactttca gcgaagagct 2800

 gtgctctttt ctgactagat tagagcgttt ggagtggaag acgtcaaatg 2850

 tgtagtgaga tggaggtttt acattgttct tctactggct gtgatgaagt 2900

 gccagaatgt ctctttagaa caagagttag attccccctt tctccttatt 2950

 gccccttccg ttttgacttc ccctttattt atttgttgtc taattagggg 3000

 ccaagtctgt aaagttttgt caaagtgagt tagaagttgt tttctcttac 3050

 tatttgtgtt taccagagtt gggagataag atagtttcca tgaaggtgtg 3100

 tatgttttat acgatgtttg ttatagggcc atgcattggt aacttgaaaa 3150

 tagaccagct taatgtcttc aggatgtaaa actctgaata cacggcgtct 3200

 ctttttcata cattgcatgt aagttgttag tacctcacaa gctacagaag 3250

 ttcagccatg agattttgtt tggcaacatg aacagatttg tgtataactg 3300

 caatggcctt tttttccaga tttccttatt gactttttgt ttgccttacc 3350

 tggggctagt tttttatgct ttgtacctag aaaacaaaaa attacattcg 3400

 ttgggctttt tttcaaggtt gggattacca caccacctgg aatatcatac 3450

 tgtggtttct gcctaaaatt ggcacatgta agtattgaag aaaatggtta 3500

 tataattcag ttgaaactct tggttattag atgttaggca tctcctgtat 3550

 gtaagacaca aggccaacca caacacagaa cgatgttgac ctgttaagta 3600

 ttctctgaaa catggccaaa atgcatttta tgagcttttt tttttgctat 3650

 tgtaaatatt agtggtttac aatgcgcttt agacatattt ctttaaaatg 3700

 caagcagtga gaaataagac ctctctgaat tagtagctct aaactgttaa 3750

 catagaatgt tacttggaaa aagtctggaa tatgtggtgt acacaagcag 3800

 tgcttcgtga atgagtttct tagcttttat agtgcgccat gtttctcaaa 3850

 gtttgttttt gttgacaaaa cattttataa tatatatctt atgtttattt 3900

 tttttctcaa ctaattgtgt actgcactgt aaggtgaaaa ttagccatcc 3950

 attatttatc ttctgtggca atgcatttat atggttgatt gggtggggaa 4000

 ttttttgcag aaagatgcaa agtgattggg ttttcgactt cctatcgcag 4050

 ggagctttta agaaatatta atttcctata catttttcca atccccatgc 4100

 aaactgttcc tgtttacata ccttctctgt tgtatcagta ctttgagtga 4150

 gaagacagtt tatttaaaac ttgagcaggc tgttcagcat tgtttctgct 4200

 tctgaaatct gtatagtaca ctggtttgta atcattatgt cttcattgaa 4250

 atccttgcta cttctcttcc tcctcaatga aatacattat atattatctt 4300

 tatgtactct taagaaaaac gagcaaggaa gagtatcttc attattctca 4350

 ttttctctga gttggaaaca aaaacatgaa ggactccaac tagaagacag 4400

 atatttacat ttaaatagat tagtgggaaa actttaagag tttccacata 4450

 ttagttttca ttttttgagt caagagactg ctccttgtac tgggagacac 4500

 tagtagtata tgtttgtaat gttactttaa aattatcttt ttattttata 4550

 aggcccataa atactggtta aactctgtta aaagtgggcc ttctatcttg 4600

 gatggtttca ctgccatcag ccatgctgat atattagaaa tggcatccct 4650

 atctacttac tttaatgctt aaaattatac ataaaatgct ttatttagaa 4700

 aacctacatg atacagtggt gtcagccttg ccatgtatca gtttcacttg 4750

 aaatttgaga ccaattaaat ttcaactgtt tagggtggag aaagaggtac 4800

 tggaaaacat gcagatgagg atatctttta tgtgcaacag tatcctttgc 4850

 atgggaggag agttactctt gaaaggcagg cagcttaagt ggacaatgtt 4900

 ttgtatatag ttgagaattt tacgacactt ttaaaaattg tgtaattgtt 4950

 aaatgtccag ttttgctctg ttttgcctga agttttagta tttgttttct 5000

 aggtggacct ctgaaaacca aaccagtacc tggggaggtt agatgtgtgt 5050

 ttcaggcttg gagtgtatga gtggttttgc ttgtattttc ctccagagat 5100

 tttgaacttt aataattgcg tgtgtgtttt tttttttttt aagtggcttt 5150

 gttttttttt ctcaagtaaa attgtgaaca tatttccttt ataggggcag 5200

 ggcatgagtt agggagactg aagagtattg tagactgtac atgtgccttc 5250

 ttaatgtgtt tctcgacaca ttttttttca gtaacttgaa aattcaaaag 5300

 ggacatttgg ttaggttact gtacatcaat ctatgcataa atggcagctt 5350

 gttttcttga gccacggtct aaattttgtt tttatagaaa ttttttatac 5400

 tgattggttc atagatggtc agttttgtac acagactgaa caatacagca 5450

 ctttgccaaa aatgagtgta gcattgttta aacattgtgt gttaacacct 5500

 gttctttgta attgggttgt ggtgcatttt gcactacctg gagttacagt 5550

 tttcaatctg tcagtaaata aagtgtcctt taacttc 5587

<210> 4289
<211> 240
<212> PRT
<213> Homo sapien

<400> 4289
 Met Phe Gln Arg Leu Asn Lys Met Phe Val Gly Glu Val Ser Ser
   1               5                  10                  15

 Ser Ser Asn Gln Glu Pro Glu Phe Asn Glu Lys Glu Asp Asp Glu
                  20                  25                  30

 Trp Ile Leu Val Asp Phe Ile Asp Thr Cys Thr Gly Phe Ser Ala
                  35                  40                  45

 Glu Glu Glu Glu Glu Glu Glu Asp Ile Ser Glu Glu Ser Pro Thr
                  50                  55                  60

 Glu His Pro Ser Val Phe Ser Cys Leu Pro Ala Ser Leu Glu Cys
                  65                  70                  75

 Leu Ala Asp Thr Ser Asp Ser Cys Phe Leu Gln Phe Glu Ser Cys
                  80                  85                  90

 Pro Met Glu Glu Ser Trp Phe Ile Thr Pro Pro Pro Cys Phe Thr
                  95                 100                 105

 Ala Gly Gly Leu Thr Thr Ile Lys Val Glu Thr Ser Pro Met Glu
                 110                 115                 120

 Asn Leu Leu Ile Glu His Pro Ser Met Ser Val Tyr Ala Val His
                 125                 130                 135

 Asn Ser Cys Pro Gly Leu Ser Glu Ala Thr Arg Gly Thr Asp Glu
                 140                 145                 150

 Leu His Ser Pro Ser Ser Pro Arg Val Glu Ala Gln Asn Glu Met
                 155                 160                 165

 Gly Gln His Ile His Cys Tyr Val Ala Ala Leu Ala Ala His Thr
                 170                 175                 180

 Thr Phe Leu Glu Gln Pro Lys Ser Phe Arg Pro Ser Gln Trp Ile
                 185                 190                 195

 Lys Glu His Ser Glu Arg Gln Pro Leu Asn Arg Asn Ser Leu Arg
                 200                 205                 210

 Arg Gln Asn Leu Thr Arg Asp Cys His Pro Arg Gln Val Lys His
                 215                 220                 225

 Asn Gly Trp Val Val His Gln Pro Cys Pro Arg Gln Tyr Asn Tyr
                 230                 235                 240

<210> 4290
<211> 966
<212> DNA
<213> Homo sapien

<400> 4290
 gagcagaagt ctgtaaatgt ccctgtgatg gacctctttc tagcatgttg 50

 cagttttatt tttaataaat ttgtaagtga aatgaacgta aaggtaattg 100

 tgtacgtttt agacatgaca atgaaaattt aaaatgtagc ttccatactt 150

 gtgcataatt ccaaagtatt ttatttttta tcaatcagtg ttaaatagct 200

 ttttgtacag gcttcaatcc atttttcgaa gtgtgctgtt ttttaatgaa 250

 agtaactata atcttttcac atcccatgga actgccgttt acacattgca 300

 actttttaaa cttaactttt ttggagggag aaaaatcccc gcttgctaaa 350

 tgatactaaa ccgttgtttg ggctcttata attaggtcct gagattttat 400

 aaaaatttag tctgtagctt tttaggttct tcactagagt tggttgtaca 450

 taaaaataat aaagaatata aagtatccca aaattctttt aaagtctgga 500

 tttttccgct aatatgtact ttagagaata ttttgttcat gcatacttcc 550

 acgttaaatt gaaaatgtct tcagcttctc ttggtaaatg tgaaccattt 600

 gttttttatt gtgcttgggg gagagggtat tttaatataa tttttgccta 650

 aatcaagaag tcccctctga atgttaattt ttaaatgtca aaatatgatg 700

 aacgatatat cttgaaagtg agattgcaat atgcttaaac ttaagtggta 750

 tttcaaaaac gagaaaattc tggaatttgt catttgaagc tccataagag 800

 aaattgatag gacttcgttt ttgatcagtc tgaatagata ccaatgtcat 850

 tgtgtgggaa ttttttttaa cttgtttatg tattattttg atccattttt 900

 ctgtggcatt tggtgcaata aaacttttga atttatcttg aacattttcc 950

 tgatgctgca tgcgat 966

<210> 4291
<211> 43
<212> PRT
<213> Homo sapien

<400> 4291
 Glu Gln Lys Ser Val Asn Val Pro Val Met Asp Leu Phe Leu Ala
   1               5                  10                  15

 Cys Cys Ser Phe Ile Phe Asn Lys Phe Val Ser Glu Met Asn Val
                  20                  25                  30

 Lys Val Ile Val Tyr Val Leu Asp Met Thr Met Lys Ile
                  35                  40

<210> 4292
<211> 7029
<212> DNA
<213> Homo sapien

<400> 4292
 atggcggcgg cggcggggaa tcgcgcctcg tcgtcgggat tcccgggcgc 50

 cagggctacg agccctgagg caggcggcgg cggaggagcc ctcaaggcga 100

 gcagcgcgcg cgcggctgcc gcgggactgc tgcgggaggc gggcagcggg 150

 ggccgcgagc gggcggactg gcggcggcgg cagctgcgca aagtgcggag 200

 tgtggagctg gaccagctgc ctgagcagcc gctcttcctt gccgcctcac 250

 cgccggcctc ctcgacttcc ccgtcgccgg agcccgcgga cgcagcgggg 300

 agtgggaccg gcttccagcc tgtggcggtg ccgccgcccc acggagccgc 350

 cagccggcgc ggcgcccacc ttaccgagtc ggtggcggcg ccggacagcg 400

 gcgcctcgag tcccgcagcg gccgagcccg gggagaagcg ggcgcccgcc 450

 gccgagccgt ctcctgcagc ggcccccgcc ggtcgtgaga tggagaataa 500

 agaaactctc aaagggttgc acaagatgga tgatcgtcca gaggaacgaa 550

 tgatcaggga gaaactgaag gcaacctgta tgccagcctg gaagcacgaa 600

 tggttggaaa ggagaaatag gcgagggcct gtggtggtaa aaccaatccc 650

 agttaaagga gatggatctg aaatgaatca cttagcagct gagtctccag 700

 gagaggtcca ggcaagtgcg gcttcaccag cttccaaagg ccgacgcagt 750

 ccttctcctg gcaactcccc atcaggtcgc acagtgaaat cagaatctcc 800

 aggagtaagg agaaaaagag tttccccagt gccttttcag agtggcagaa 850

 tcacaccacc ccgaagagcc ccttcaccag atggcttctc accatatagc 900

 cctgaggaaa caaaccgccg tgttaacaaa gtgatgcggg ccagactgta 950

 cttactgcag cagatagggc ctaactcttt cctgattgga ggagacagcc 1000

 cagacaataa ataccgggtg tttattgggc ctcagaactg cagctgtgca 1050

 cgtggaacat tctgtattca tctgctattt gtgatgctcc gggtgtttca 1100

 actagaacct tcagacccaa tgttatggag aaaaacttta aagaattttg 1150

 aggttgagag tttgttccag aaatatcaca gtaagcgtag ctcaaggatc 1200

 aaagctccat ctcgtaacac catccagaag tttgtttcac gcatgtcaaa 1250

 ttctcataca ttgtcatcat ctagtacttc tacatctagt tcagaaaaca 1300

 gcataaagga tgaagaggaa cagatgtgtc ctatttgctt gttgggcatg 1350

 cttgatgaag aaagtcttac agtgtgtgaa gacggctgca ggaacaagct 1400

 gcaccaccac tgcatgtcaa tttgggcaga agagtgtaga agaaatagag 1450

 aacctttaat atgtcccctt tgtagatcta agtggagatc tcatgatttc 1500

 tacagccacg agttgtcaag tcctgtggat tccccttctt ccctcagagc 1550

 tgcacagcag caaaccgtac agcagcagcc tttggctgga tcacgaagga 1600

 atcaagagag caattttaac cttactcatt atggaactca gcaaatccct 1650

 cctgcttaca aagatttagc tgagccatgg attcaggtgt ttggaatgga 1700

 actcgttggc tgcttatttt ctagaaactg gaatgtgaga gagatggccc 1750

 tcaggcgtct ttcccatgat gtcagtgggg ccctgctgtt ggcaaatggg 1800

 gagagcactg gaaattctgg gggcagcagt ggaagcagcc cgagtggggg 1850

 agccaccagt gggtcttccc agaccagtat ctcaggagat gtggtggagg 1900

 catgctgcag cgttctgtca atggtctgtg ctgaccctgt ctacaaagtg 1950

 tacgttgctg ctttaaaaac attgagagcc atgctggtat atactccttg 2000

 ccacagttta gcggaaagaa tcaaacttca gagacttctc cagccagttg 2050

 tagacaccat cctagtcaaa tgtgcagatg ccaatagccg cacaagtcag 2100

 ctgtccatat caacactgtt ggaactgtgc aaaggccaag caggagagtt 2150

 ggcagttggc agagaaatac taaaagctgg atccattggt attggtggtg 2200

 ttgattatgt cttaaattgt attcttggaa accaaactga atcaaacaat 2250

 tggcaagaac ttcttggccg cctttgtctt atagatagac tgttgttgga 2300

 atttcctgct gaattttatc ctcatattgt cagtactgat gtttcacaag 2350

 ctgagcctgt tgaaatcagg tataagaagc tgctgtccct cttaaccttt 2400

 gctttgcagt ccattaataa ttcccactca atggttggca aactttccag 2450

 aaggatctac ttgagttctg caagaatggt tactacagta ccccatgtgt 2500

 tttcaaaact gttagaaatg ctgagtgttt ccagttccac tcacttcacc 2550

 aggatgcgtc gccgtttgat ggctattgca gatgaggtgg aaattgccga 2600

 agccatccag ttgggcgtag aagacacttt ggatggtcaa caggacagct 2650

 tcttgcaggc atctgttccc aacaactatc tggaaaccac agagaacagt 2700

 tcccctgagt gcacaatcca tttagagaaa actggaaaag gattatgtgc 2750

 tacaaaattg agtgccagtt cagaggacat ttctgagaga ctggccagca 2800

 tttcagtagg accttctagt tcaactacta actactacta caacaacaga 2850

 gcaaccaaag ccaatggttc aaacaaaagg cagaccccac agtcagtgtt 2900

 tgaactcctc tcctttatct catcattccc aattaatgtt tccagccttg 2950

 tcaacccctt cttcttctac cccatctgta ccagctggca ctgcaacaga 3000

 tgtctctaag catagacttc agggattcat tccctgcaga ataccttctg 3050

 catctcctca aacacagcgc aagttttctc tacaattcca cagaaactgt 3100

 cctgaaaaca aagactcaga taaactttcc ccagtcttta ctcagtcaag 3150

 acccttgccc tccagtaaca tacacaggcc aaagccatct cgacctaccc 3200

 caggtaatac aagtaaacag ggagatccct caaaaaatag catgacactt 3250

 gatctgaaca gtagttccaa atgtgatgac agctttggct gtagcagcaa 3300

 tagtagtaat gctgttatac ccagtgacga gacagtgttc accccagtag 3350

 aggagaaatg cagattagat gtcaatacag agctcaactc cagtattgag 3400

 gaccttcttg aagcatctat gccttcaagt gatacaacag taacttttaa 3450

 gtcagaagtt gctgtcctgt ctcctgaaaa ggctgaaaat gatgatacct 3500

 acaaagatga tgtgaatcat aatcaaaagt gcaaagagaa gatggaagct 3550

 gaagaagaag aagctttagc aattgccatg gcaatgtcag cgtctcagga 3600

 tgccctcccc atagttcctc agctgcaggt tgaaaatgga gaagatatca 3650

 tcattattca acaggataca ccagagactc taccaggaca taccaaagca 3700

 aaacaaccgt atagagaaga cactgaatgg ctgaaaggtc aacagatagg 3750

 ccttggagca ttttcttctt gttatcaggc tcaagatgtg ggaactggaa 3800

 ctttaatggc tgttaaacag gtgacttatg tcagaaacac atcttctgag 3850

 caagaagaag tagtagaagc actaagagaa gagataagaa tgatgagcca 3900

 tctgaatcat ccaaacatca ttaggatgtt gggagccacg tgtgagaaga 3950

 gcaattacaa tctcttcatt gaatggatgg cagggggatc ggtggctcat 4000

 ttgctgagta aatatggagc cttcaaagaa tcagtagtta ttaactacac 4050

 tgaacagtta ctccgtggcc tttcgtatct ccatgaaaac caaatcattc 4100

 acagagatgt caaaggtgcc aatttgctaa ttgacagcac tggtcagaga 4150

 ctaagaattg cagattttgg agctgcagcc aggttggcat caaaaggaac 4200

 tggtgcagga gagtttcagg gacaattact ggggacaatt gcatttatgg 4250

 cacctgaggt actaagaggt caacagtatg gaaggagctg tgatgtatgg 4300

 agtgttggct gtgctattat agaaatggct tgtgcaaaac caccatggaa 4350

 tgcagaaaaa cactccaatc atcttgcttt gatatttaag attgctagtg 4400

 caactactgc tccatcgatc ccttcacatt tgtctcctgg tttacgagat 4450

 gtggctcttc gttgtttaga acttcaacct caggacagac ctccatcaag 4500

 agagctactg aagcatccag tctttcgtac tacatggtag ccaattatgc 4550

 agatcaacta cagtagaaac aggatgctca acaagagaaa aaaaacttgt 4600

 ggggaaccac attgatattc tactggccat gatgccactg aacagctatg 4650

 aacgaggcca gtggggaacc cttacctaag tatgtgattg acaaatcatg 4700

 atctgtacct aagctcagta tgcaaaagcc caaactagtg cagaaactgt 4750

 aaactgtgcc tttcaaagaa ctggccctag gtgaacagga aaacaatgaa 4800

 gtttgcatga ctaaattgca gaagcataat tttatttttt tggagcactt 4850

 tttcagcaat attagcggct gaggggctca ggatctattt taatatttca 4900

 attattcttc catttcatat agtgatcaca agcagggggt tctgcaattc 4950

 cgttcaaatt ttttgtcact ggctataaaa tcagtatctg cctcttttag 5000

 gtcagagtat gctatgagta gcaatacata catatatttt taaaagttga 5050

 tacttcttta tgacccacag ttgaccttta ttttcttaaa taccagggca 5100

 gttgtggctc attgtgcatt ttactgttgg cccattcatt tcgtttttgg 5150

 aaattatggt tttgtatttt catgtttatt tacattcatt tttgtttatt 5200

 cagggaaagc tgatcttttt ttcaaaccag aaaaaaaaaa tgaactagat 5250

 atgaagtaga gttcattaaa tatcttgcta ttgtcagagt ttttaaaata 5300

 tagacttaat tttgtttttt taaattggaa tacaataaag tactacctac 5350

 atttgagtca gtcaccactc ttattgtgca ggttaagtac aagttaacta 5400

 aaaataaact gtcctctctg gtgcaactca caaccaagat caagattacc 5450

 ttaaaattta tttgaatttt ttagatgttt tggttgtcaa actgtaggaa 5500

 acttcacaac atttaagtct tactctgtat gtaacaatcc atcattcacc 5550

 ttcactactg gtaataacat agagctgcca ttttcctttt accatgcatc 5600

 atctctttac agtaggcctg gcagatcatt ttttaaaaag attattcaac 5650

 taccaatcag taatgttttt aaacagtaca tttgctttga acttggaaaa 5700

 tgtgttcaga aagaaaaatg gaattgaatt tcatttatac actaattcct 5750

 tggattttgc acagttacct aacggtttta gtctggagtt aaattcagat 5800

 gcatggaatc ctgaaggaaa atggtagctt tttaatcttt ttgtgtgtgt 5850

 gtgagtcttt taaatcaagt actgattaac tattaagtac aactttgaga 5900

 ttttagtttt aactcttcag aagccagtgt gaaatagaat tggttattct 5950

 caaagactca ggataaacta aataagctat atatagagta catttaaaat 6000

 gtacaacaca aattggaagt aaaataagtt acaagataag tttacaggga 6050

 tatattgctt acaattttta aaaggcagtt tgttttttat gtgaatatgt 6100

 ttcttagtga aattttacat tcctttgttt tggaagattg gcgatatttg 6150

 aagagttaaa aatagtacag aaatgtgaag tttggtatct ctaaatgtgt 6200

 tgtacttgac tttctttttt attttttttt attttttttg actacttaga 6250

 attttcacaa ttctaataag attgtttcca agtctctcat gtgcaagctt 6300

 taaaggatgc actcttgcca ttttatgtac tggaagatca ttggtcagat 6350

 gaatactgtg tctgacaaaa atgtaaactg tataaactga ggaacctcag 6400

 ctaatcagta ttactttgta gatcaccatg cccaccacat ttcaaactca 6450

 aactatctgt agatttcaaa atccattgtg tttgagtttg tttgcagttc 6500

 cctcagcttg ctggtaattg tggtgttttg ttttttgttt tgttttcaat 6550

 gcaaatgtga tgtaatattc ttattttctt tggatcaaag ctggactgga 6600

 aattgtatcg tgtaattatt tttgtgttct taatgttatt tggtactcaa 6650

 gttgtaaata acgtctacta ctgtttattc cagtttctac tacctcaggt 6700

 gtcctataga tttttcttct accaaagttc actttcacaa tgaaattata 6750

 tttgctgtgt gactatgatt cctaagattt ccagggctta agggctaact 6800

 tctattagca ccttactgtg taagcaaatg ttacaaaaaa agacaagaaa 6850

 aaaatctctg ggttaagaaa atttggctta aatgtatcct ttgttatttt 6900

 aaatatattg agatatttta attaaaattt ttaccccatt gaaccgattt 6950

 tatagtattt gtacctattt tggtgttttt gtctttatag taaataaaag 7000

 tttttgaaca aaaaaaaaag tcgacgcgg 7029

<210> 4293
<211> 1512
<212> PRT
<213> Homo sapien

<400> 4293
 Met Ala Ala Ala Ala Gly Asn Arg Ala Ser Ser Ser Gly Phe Pro
   1               5                  10                  15

 Gly Ala Arg Ala Thr Ser Pro Glu Ala Gly Gly Gly Gly Gly Ala
                  20                  25                  30

 Leu Lys Ala Ser Ser Ala Arg Ala Ala Ala Ala Gly Leu Leu Arg
                  35                  40                  45

 Glu Ala Gly Ser Gly Gly Arg Glu Arg Ala Asp Trp Arg Arg Arg
                  50                  55                  60

 Gln Leu Arg Lys Val Arg Ser Val Glu Leu Asp Gln Leu Pro Glu
                  65                  70                  75

 Gln Pro Leu Phe Leu Ala Ala Ser Pro Pro Ala Ser Ser Thr Ser
                  80                  85                  90

 Pro Ser Pro Glu Pro Ala Asp Ala Ala Gly Ser Gly Thr Gly Phe
                  95                 100                 105

 Gln Pro Val Ala Val Pro Pro Pro His Gly Ala Ala Ser Arg Arg
                 110                 115                 120

 Gly Ala His Leu Thr Glu Ser Val Ala Ala Pro Asp Ser Gly Ala
                 125                 130                 135

 Ser Ser Pro Ala Ala Ala Glu Pro Gly Glu Lys Arg Ala Pro Ala
                 140                 145                 150

 Ala Glu Pro Ser Pro Ala Ala Ala Pro Ala Gly Arg Glu Met Glu
                 155                 160                 165

 Asn Lys Glu Thr Leu Lys Gly Leu His Lys Met Asp Asp Arg Pro
                 170                 175                 180

 Glu Glu Arg Met Ile Arg Glu Lys Leu Lys Ala Thr Cys Met Pro
                 185                 190                 195

 Ala Trp Lys His Glu Trp Leu Glu Arg Arg Asn Arg Arg Gly Pro
                 200                 205                 210

 Val Val Val Lys Pro Ile Pro Val Lys Gly Asp Gly Ser Glu Met
                 215                 220                 225

 Asn His Leu Ala Ala Glu Ser Pro Gly Glu Val Gln Ala Ser Ala
                 230                 235                 240

 Ala Ser Pro Ala Ser Lys Gly Arg Arg Ser Pro Ser Pro Gly Asn
                 245                 250                 255

 Ser Pro Ser Gly Arg Thr Val Lys Ser Glu Ser Pro Gly Val Arg
                 260                 265                 270

 Arg Lys Arg Val Ser Pro Val Pro Phe Gln Ser Gly Arg Ile Thr
                 275                 280                 285

 Pro Pro Arg Arg Ala Pro Ser Pro Asp Gly Phe Ser Pro Tyr Ser
                 290                 295                 300

 Pro Glu Glu Thr Asn Arg Arg Val Asn Lys Val Met Arg Ala Arg
                 305                 310                 315

 Leu Tyr Leu Leu Gln Gln Ile Gly Pro Asn Ser Phe Leu Ile Gly
                 320                 325                 330

 Gly Asp Ser Pro Asp Asn Lys Tyr Arg Val Phe Ile Gly Pro Gln
                 335                 340                 345

 Asn Cys Ser Cys Ala Arg Gly Thr Phe Cys Ile His Leu Leu Phe
                 350                 355                 360

 Val Met Leu Arg Val Phe Gln Leu Glu Pro Ser Asp Pro Met Leu
                 365                 370                 375

 Trp Arg Lys Thr Leu Lys Asn Phe Glu Val Glu Ser Leu Phe Gln
                 380                 385                 390

 Lys Tyr His Ser Lys Arg Ser Ser Arg Ile Lys Ala Pro Ser Arg
                 395                 400                 405

 Asn Thr Ile Gln Lys Phe Val Ser Arg Met Ser Asn Ser His Thr
                 410                 415                 420

 Leu Ser Ser Ser Ser Thr Ser Thr Ser Ser Ser Glu Asn Ser Ile
                 425                 430                 435

 Lys Asp Glu Glu Glu Gln Met Cys Pro Ile Cys Leu Leu Gly Met
                 440                 445                 450

 Leu Asp Glu Glu Ser Leu Thr Val Cys Glu Asp Gly Cys Arg Asn
                 455                 460                 465

 Lys Leu His His His Cys Met Ser Ile Trp Ala Glu Glu Cys Arg
                 470                 475                 480

 Arg Asn Arg Glu Pro Leu Ile Cys Pro Leu Cys Arg Ser Lys Trp
                 485                 490                 495

 Arg Ser His Asp Phe Tyr Ser His Glu Leu Ser Ser Pro Val Asp
                 500                 505                 510

 Ser Pro Ser Ser Leu Arg Ala Ala Gln Gln Gln Thr Val Gln Gln
                 515                 520                 525

 Gln Pro Leu Ala Gly Ser Arg Arg Asn Gln Glu Ser Asn Phe Asn
                 530                 535                 540

 Leu Thr His Tyr Gly Thr Gln Gln Ile Pro Pro Ala Tyr Lys Asp
                 545                 550                 555

 Leu Ala Glu Pro Trp Ile Gln Val Phe Gly Met Glu Leu Val Gly
                 560                 565                 570

 Cys Leu Phe Ser Arg Asn Trp Asn Val Arg Glu Met Ala Leu Arg
                 575                 580                 585

 Arg Leu Ser His Asp Val Ser Gly Ala Leu Leu Leu Ala Asn Gly
                 590                 595                 600

 Glu Ser Thr Gly Asn Ser Gly Gly Ser Ser Gly Ser Ser Pro Ser
                 605                 610                 615

 Gly Gly Ala Thr Ser Gly Ser Ser Gln Thr Ser Ile Ser Gly Asp
                 620                 625                 630

 Val Val Glu Ala Cys Cys Ser Val Leu Ser Met Val Cys Ala Asp
                 635                 640                 645

 Pro Val Tyr Lys Val Tyr Val Ala Ala Leu Lys Thr Leu Arg Ala
                 650                 655                 660

 Met Leu Val Tyr Thr Pro Cys His Ser Leu Ala Glu Arg Ile Lys
                 665                 670                 675

 Leu Gln Arg Leu Leu Gln Pro Val Val Asp Thr Ile Leu Val Lys
                 680                 685                 690

 Cys Ala Asp Ala Asn Ser Arg Thr Ser Gln Leu Ser Ile Ser Thr
                 695                 700                 705

 Leu Leu Glu Leu Cys Lys Gly Gln Ala Gly Glu Leu Ala Val Gly
                 710                 715                 720

 Arg Glu Ile Leu Lys Ala Gly Ser Ile Gly Ile Gly Gly Val Asp
                 725                 730                 735

 Tyr Val Leu Asn Cys Ile Leu Gly Asn Gln Thr Glu Ser Asn Asn
                 740                 745                 750

 Trp Gln Glu Leu Leu Gly Arg Leu Cys Leu Ile Asp Arg Leu Leu
                 755                 760                 765

 Leu Glu Phe Pro Ala Glu Phe Tyr Pro His Ile Val Ser Thr Asp
                 770                 775                 780

 Val Ser Gln Ala Glu Pro Val Glu Ile Arg Tyr Lys Lys Leu Leu
                 785                 790                 795

 Ser Leu Leu Thr Phe Ala Leu Gln Ser Ile Asn Asn Ser His Ser
                 800                 805                 810

 Met Val Gly Lys Leu Ser Arg Arg Ile Tyr Leu Ser Ser Ala Arg
                 815                 820                 825

 Met Val Thr Thr Val Pro His Val Phe Ser Lys Leu Leu Glu Met
                 830                 835                 840

 Leu Ser Val Ser Ser Ser Thr His Phe Thr Arg Met Arg Arg Arg
                 845                 850                 855

 Leu Met Ala Ile Ala Asp Glu Val Glu Ile Ala Glu Ala Ile Gln
                 860                 865                 870

 Leu Gly Val Glu Asp Thr Leu Asp Gly Gln Gln Asp Ser Phe Leu
                 875                 880                 885

 Gln Ala Ser Val Pro Asn Asn Tyr Leu Glu Thr Thr Glu Asn Ser
                 890                 895                 900

 Ser Pro Glu Cys Thr Ile His Leu Glu Lys Thr Gly Lys Gly Leu
                 905                 910                 915

 Cys Ala Thr Lys Leu Ser Ala Ser Ser Glu Asp Ile Ser Glu Arg
                 920                 925                 930

 Leu Ala Ser Ile Ser Val Gly Pro Ser Ser Ser Thr Thr Asn Tyr
                 935                 940                 945

 Tyr Tyr Asn Asn Arg Ala Thr Lys Ala Asn Gly Ser Asn Lys Arg
                 950                 955                 960

 Gln Thr Pro Gln Ser Val Phe Glu Leu Leu Ser Phe Ile Ser Ser
                 965                 970                 975

 Phe Pro Ile Asn Val Ser Ser Leu Val Asn Pro Phe Phe Phe Tyr
                 980                 985                 990

 Pro Ile Cys Thr Ser Trp His Cys Asn Arg Cys Leu Lys His Arg
                 995                1000                1005

 Leu Gln Gly Phe Ile Pro Cys Arg Ile Pro Ser Ala Ser Pro Gln
                1010                1015                1020

 Thr Gln Arg Lys Phe Ser Leu Gln Phe His Arg Asn Cys Pro Glu
                1025                1030                1035

 Asn Lys Asp Ser Asp Lys Leu Ser Pro Val Phe Thr Gln Ser Arg
                1040                1045                1050

 Pro Leu Pro Ser Ser Asn Ile His Arg Pro Lys Pro Ser Arg Pro
                1055                1060                1065

 Thr Pro Gly Asn Thr Ser Lys Gln Gly Asp Pro Ser Lys Asn Ser
                1070                1075                1080

 Met Thr Leu Asp Leu Asn Ser Ser Ser Lys Cys Asp Asp Ser Phe
                1085                1090                1095

 Gly Cys Ser Ser Asn Ser Ser Asn Ala Val Ile Pro Ser Asp Glu
                1100                1105                1110

 Thr Val Phe Thr Pro Val Glu Glu Lys Cys Arg Leu Asp Val Asn
                1115                1120                1125

 Thr Glu Leu Asn Ser Ser Ile Glu Asp Leu Leu Glu Ala Ser Met
                1130                1135                1140

 Pro Ser Ser Asp Thr Thr Val Thr Phe Lys Ser Glu Val Ala Val
                1145                1150                1155

 Leu Ser Pro Glu Lys Ala Glu Asn Asp Asp Thr Tyr Lys Asp Asp
                1160                1165                1170

 Val Asn His Asn Gln Lys Cys Lys Glu Lys Met Glu Ala Glu Glu
                1175                1180                1185

 Glu Glu Ala Leu Ala Ile Ala Met Ala Met Ser Ala Ser Gln Asp
                1190                1195                1200

 Ala Leu Pro Ile Val Pro Gln Leu Gln Val Glu Asn Gly Glu Asp
                1205                1210                1215

 Ile Ile Ile Ile Gln Gln Asp Thr Pro Glu Thr Leu Pro Gly His
                1220                1225                1230

 Thr Lys Ala Lys Gln Pro Tyr Arg Glu Asp Thr Glu Trp Leu Lys
                1235                1240                1245

 Gly Gln Gln Ile Gly Leu Gly Ala Phe Ser Ser Cys Tyr Gln Ala
                1250                1255                1260

 Gln Asp Val Gly Thr Gly Thr Leu Met Ala Val Lys Gln Val Thr
                1265                1270                1275

 Tyr Val Arg Asn Thr Ser Ser Glu Gln Glu Glu Val Val Glu Ala
                1280                1285                1290

 Leu Arg Glu Glu Ile Arg Met Met Ser His Leu Asn His Pro Asn
                1295                1300                1305

 Ile Ile Arg Met Leu Gly Ala Thr Cys Glu Lys Ser Asn Tyr Asn
                1310                1315                1320

 Leu Phe Ile Glu Trp Met Ala Gly Gly Ser Val Ala His Leu Leu
                1325                1330                1335

 Ser Lys Tyr Gly Ala Phe Lys Glu Ser Val Val Ile Asn Tyr Thr
                1340                1345                1350

 Glu Gln Leu Leu Arg Gly Leu Ser Tyr Leu His Glu Asn Gln Ile
                1355                1360                1365

 Ile His Arg Asp Val Lys Gly Ala Asn Leu Leu Ile Asp Ser Thr
                1370                1375                1380

 Gly Gln Arg Leu Arg Ile Ala Asp Phe Gly Ala Ala Ala Arg Leu
                1385                1390                1395

 Ala Ser Lys Gly Thr Gly Ala Gly Glu Phe Gln Gly Gln Leu Leu
                1400                1405                1410

 Gly Thr Ile Ala Phe Met Ala Pro Glu Val Leu Arg Gly Gln Gln
                1415                1420                1425

 Tyr Gly Arg Ser Cys Asp Val Trp Ser Val Gly Cys Ala Ile Ile
                1430                1435                1440

 Glu Met Ala Cys Ala Lys Pro Pro Trp Asn Ala Glu Lys His Ser
                1445                1450                1455

 Asn His Leu Ala Leu Ile Phe Lys Ile Ala Ser Ala Thr Thr Ala
                1460                1465                1470

 Pro Ser Ile Pro Ser His Leu Ser Pro Gly Leu Arg Asp Val Ala
                1475                1480                1485

 Leu Arg Cys Leu Glu Leu Gln Pro Gln Asp Arg Pro Pro Ser Arg
                1490                1495                1500

 Glu Leu Leu Lys His Pro Val Phe Arg Thr Thr Trp
                1505                1510

<210> 4294
<211> 5949
<212> DNA
<213> Homo sapien

<400> 4294
 gtccccaggc gtggctacag ttggtgaaga atctttccat gccgctggag 50

 ctcatctgct ccgatgagca catgcaaggc agcgggagcc tggcccaggc 100

 tgtcatcagg gaagtcagag cccagtggag tcggattttc tccaccgcac 150

 tcttcgtgga gcacgtgctc ctaggaaccg agagccgcgt ccccgagtta 200

 caggggctgg tgaccgagca cgtcttctta ctagacaagt gtcttcgaga 250

 gaactctgac gtgaagacgc acgggccttt tgaggccgtg atgcgcactc 300

 tctgtgaatg caaggagaca gccagcaaga ccctcagcag gtttgggatt 350

 cagccgtgct ccatctgcct gggagatgca aaggaccccg tctgtctgcc 400

 ctgcgaccac gtgcactgcc tgcgctgcct cagggcctgg tttgcctcag 450

 agcagatgat atgcccctac tgtttaactg ccttgccaga cgaattctct 500

 ccagctgttt cccaagcgca cagggaagcc attgaaaagc atgcccgctt 550

 ccggcagatg tgcaacagtt tcttcgtaga cctggtgtcc accatttgct 600

 tcaaggacaa cgctccgcct gagaaggaag tgattgagag cctgctctct 650

 ctcctcttcg tccaaaaggg gcgcttaaga gatgctgccc agagacactg 700

 tgaacacaca aaatctctct ctccattcaa tgatgttgtg gataagactc 750

 ctgtcatccg ctcagtgata ctgaaactgc ttttgaagta cagctttcat 800

 gatgtaaaag attatattca ggaatatttg accctgttaa aaaagaaagc 850

 attcataact gaagataaaa ctgaactgta catgctcttc atcaactgcc 900

 tggaggattc aatacttgag aagaccagtg cttactccag aaatgatgaa 950

 ctgaaccacc tagaagagga aggtcgtttc cttaaggcat attctccagc 1000

 aagccggggc cgagagcctg ccaacgaggc ctcggttgaa tacctgcaag 1050

 aggtggcccg gatccgcctc tgcctcgaca gagctgcaga tttcctctcg 1100

 gagcctgagg gaggcccaga gatggccaag gagaagcagt gctacctgca 1150

 gcaagtcaag cagttctgta tccgggtgga gaacgactgg caccgggtgt 1200

 acctggtgcg gaagctcagc agccagcggg ggatggagtt cgtgcagggc 1250

 ctctccaagc ccggccgccc gcaccagtgg gtgtttccca aggacgttgt 1300

 caagcagcag gggctgcggc aggaccaccc aggccagatg gataggtacc 1350

 tggtgtacgg cgatgaatac aaggctctcc gtgatgctgt ggccaaagct 1400

 gtcctcgagt gcaagccact gggcattaag actgctctga aggcctgcaa 1450

 gaccccccaa agccagcagt cagcctactt cctgttaaca ctgtttagag 1500

 aggtggctat tttgtacaga tcccacaatg caagcctcca ccccacgcca 1550

 gagcaatgtg aagctgtgag caaattcatt ggcgaatgca agatcctttc 1600

 acctcctgat atcagccgtt ttgcaacatc gctcgtggac aattctgtgc 1650

 cattgttgag ggcggggcct agtgacagca accttgatgg aacggtgaca 1700

 gaaatggcca ttcatgctgc agccgtcctt ctgtgtggac agaatgaact 1750

 cttggagccc ctaaagaatc tggccttctc cccagccacc atggcgcatg 1800

 cttttcttcc aaccatgcct gaagacttgc tggctcaagc tcggaggtgg 1850

 aagggtctgg agcgagtcca ctggtacact tgtcccaacg gccatccttg 1900

 ctccgtggga gagtgtggca ggccgatgga acagagcatc tgcattgact 1950

 gccatgcgcc gattggaggc attgaccaca aacctcggga cggctttcat 2000

 ctggtcaaag acaaggcaga cagaacgcag accggccatg tgctgggcaa 2050

 cccgcagcgg agagacgtgg tgacatgtga ccgagggctg cccccagtgg 2100

 tcttcctcct tatccggcta ctcactcact tggctctgct tctgggagcg 2150

 tcccagagtt cccaggctct gataaacatc attaagcctc cagtgaggga 2200

 tccaaaaggc tttctgcagc agcacatcct gaaggacctg gagcagttgg 2250

 ccaagatgct gggacacagt gccgacgaga ccatcggcgt ggtccacctc 2300

 gtcctgcgca ggcttctcca agagcagcac cagctctcta gcagaaggct 2350

 tttaaatttt gacacagaat tgtcaactaa agaaatgagg aacaactggg 2400

 aaaaggaaat cgcagctgtg atttctcctg aactggagca tctagataaa 2450

 acccttccca ccatgaataa tctcatcagc caagataagc gtatcagctc 2500

 taaccctgtg gccaaaataa tatatggtga cccagtgacc ttcctgcccc 2550

 acctgccccg gaaaagtgtg gtccattgct ctaagatttg gagctgcagg 2600

 aaaagaatta cagttgagta cctccagcac attgtggaac agaaaaatgg 2650

 caaagaaaga gtgcccatcc tctggcattt cctgcagaag gaagcagagc 2700

 tgaggctggt aaagttcctg cctgagattt tggccttgca aagggatcta 2750

 gtgaagcagt tccagaacgt ccagcaagtt gaatacagct ccatcagagg 2800

 cttcctcagc aagcacagct cagatgggtt gaggcagctg cttcacaaca 2850

 ggatcacagt ctttctgtcc acatggaaca aactgaggag atcgcttgag 2900

 acgaacggtg agatcaacct acccaaagac tactgcagca ctgacttgga 2950

 tctggacact gagtttgaga tcctcttgcc acgccgacgg ggcctgggcc 3000

 tctgtgctac cgctctcgtc agctacttga ttcgcctaca caatgaaatt 3050

 gtctacgccg tggaaaaact ctccaaggaa aacaacagct attccgtgga 3100

 tgccgccgag gtcactgaac tgcatgtcat cagttatgaa gtggagcggg 3150

 acctgactcc actgattctc tccaactgcc agtaccaggt ggaggagggc 3200

 agagagaccg tgcaggagtt cgatctggag aagattcagc ggcagatcgt 3250

 cagccgcttc ctccagggca agccccggct gagcctcaag ggaataccca 3300

 ctctggtgta cagacacgac tggaactatg aacatctctt tatggacatc 3350

 aagaacaaaa tggcacagga ctccctcccc agctcggtca ttagtgccat 3400

 cagtggacag ctgcagtcct acagcgatgc ctgtgaagtg ctgtctgtcg 3450

 tagaagtcac tctggggttt ctgagcacag ctggtgggga tccaaacatg 3500

 cagctgaatg tgtatactca agacatcctg caaatgggtg atcagacgat 3550

 tcacgtgtta aaggccttaa acagatgcca gttaaaacac accattgccc 3600

 tctggcagtt cctgtctgct cataagtctg aacagctgct gcggctgcac 3650

 aaagagccat ttggggaaat cagttcaagg tacaaagcgg atctgagccc 3700

 ggaaaatgct aagctcctca gcacattcct aaatcagact ggcctagacg 3750

 ccttcctgct agagctgcac gaaatgataa tcttgaaact aaagaacccc 3800

 caaacccaaa ccgaggagcg cttccgccct cagtggagcc tgagagacac 3850

 tctcgtaagt tacatgcaaa ctaaagaaag tgaaattctt cctgaaatgg 3900

 catctcagtt cccagaagag atactgctcg ccagctgtgt ctcagtgtgg 3950

 aaaacagctg ctgtgctgaa atggaatcga gaaatgagat agaattattt 4000

 cctcagctat ctttggatga ctttggagag aagactcctc tctcctcgtc 4050

 tgcggcgtgg acttgatcat ggactggtgc ctttgcattc agaaggagag 4100

 ctgtcagcgt agcaccgaat tcaagaccaa ggcgtgctac ctgagctgac 4150

 agctttttga aagccgagct gtttctgaac catgtacata catgttctga 4200

 aactttctca tcattttatg agtactgttc attgagagat gacaatgaag 4250

 attagatgaa attggaaata aaccaacatt gtttacattc caggagactt 4300

 gtagctcagc cacacacgca gtaatgacct gtgcccgttc gcctctggca 4350

 ctgcccaccc ctcttttttt tttcttctaa ttctgtactc acaaaagaga 4400

 atctcatttt cttctttctt ccattccctt aaattctgag tactgtacat 4450

 atatttctgg gttcccacga tgatgtgaaa aactaccaga ctgttttttg 4500

 tcttctcaca aagacaagaa aaatcagggc attttgtgag tgccttaaga 4550

 tcaaactaac aagatctgac cctctcccct cacagtgagc cactgcccca 4600

 cttcagaggg taagagccaa aagcctcatt gtgaaaggca ctggacttgg 4650

 accagggaca ccatcagggc cttggttttc tcacgcataa aatggagagt 4700

 ggattaatcg ccaaagattc ttctgatctg acattttgaa attgtgagag 4750

 aaactagatg actgtaaact tggtcacagg cctggttctg gcagttcttt 4800

 gcggactttt ttctagcatt atgccaaata aacatgcagt ctcagtgtgc 4850

 tctcgcatgt atgaatatct agtcctttct gtggttctca gccaagacat 4900

 aaaaactagg actcagagca catacaaaac cagttatgtt tcggaaagag 4950

 ggaaaagagt ccccgagccc ggatcttgtg ctgcttttct cactgacgtg 5000

 ttgccttttt tctttacaaa atctgctttg atacttagga cctctctgga 5050

 ctaatttctc ttcctagaca gctcagcaca gctattgata tgttagaggc 5100

 agtatcctta atattcattc taaatgagtt aacgacttaa cttgaaattg 5150

 ggcctaagga gtgagaacta caaaaataca aaatgcttgt ccaggactca 5200

 gccatgcaca ccttgagcag cgccggcagg aggcacggaa ggaactgtgc 5250

 tccgttctcc tcactgtcat ggtgccacca gtgtctgatg aagggcagag 5300

 tgacccagac tgcaggcagt aactgacttc acacagtccc tggcatttag 5350

 tcatctgtga ttgttttatc actctggact gtgcagagcc acctgccacc 5400

 gagatctgca ttccgactgc ctatgaacgg gtgtgggggc cgggggctgg 5450

 cttgctgaag tcttcaactt gcactcggag ctcctttgat acctcagagc 5500

 tggctgtcag gtggcagctc acacccagac tcactggcca cacctcagca 5550

 gggggggagt cgagtgtcag tctctttctg tgaaggcttt ttttttcctt 5600

 tggcctggga atttttccca tttttatgaa ggggttttaa attgtttcat 5650

 tttgtgtgct gtgcttcaaa gccttaactg tcaaatcttg cattatcttg 5700

 tttgtacaga aatatactgg cctagcagag gcaaaaaaaa aaaaaatgaa 5750

 ttttatttta cttgtcacac ctgtcttaat aaactggagt tttgctgcta 5800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 5850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 5900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 5949

<210> 4295
<211> 1329
<212> PRT
<213> Homo sapien

<400> 4295
 Pro Gln Ala Trp Leu Gln Leu Val Lys Asn Leu Ser Met Pro Leu
   1               5                  10                  15

 Glu Leu Ile Cys Ser Asp Glu His Met Gln Gly Ser Gly Ser Leu
                  20                  25                  30

 Ala Gln Ala Val Ile Arg Glu Val Arg Ala Gln Trp Ser Arg Ile
                  35                  40                  45

 Phe Ser Thr Ala Leu Phe Val Glu His Val Leu Leu Gly Thr Glu
                  50                  55                  60

 Ser Arg Val Pro Glu Leu Gln Gly Leu Val Thr Glu His Val Phe
                  65                  70                  75

 Leu Leu Asp Lys Cys Leu Arg Glu Asn Ser Asp Val Lys Thr His
                  80                  85                  90

 Gly Pro Phe Glu Ala Val Met Arg Thr Leu Cys Glu Cys Lys Glu
                  95                 100                 105

 Thr Ala Ser Lys Thr Leu Ser Arg Phe Gly Ile Gln Pro Cys Ser
                 110                 115                 120

 Ile Cys Leu Gly Asp Ala Lys Asp Pro Val Cys Leu Pro Cys Asp
                 125                 130                 135

 His Val His Cys Leu Arg Cys Leu Arg Ala Trp Phe Ala Ser Glu
                 140                 145                 150

 Gln Met Ile Cys Pro Tyr Cys Leu Thr Ala Leu Pro Asp Glu Phe
                 155                 160                 165

 Ser Pro Ala Val Ser Gln Ala His Arg Glu Ala Ile Glu Lys His
                 170                 175                 180

 Ala Arg Phe Arg Gln Met Cys Asn Ser Phe Phe Val Asp Leu Val
                 185                 190                 195

 Ser Thr Ile Cys Phe Lys Asp Asn Ala Pro Pro Glu Lys Glu Val
                 200                 205                 210

 Ile Glu Ser Leu Leu Ser Leu Leu Phe Val Gln Lys Gly Arg Leu
                 215                 220                 225

 Arg Asp Ala Ala Gln Arg His Cys Glu His Thr Lys Ser Leu Ser
                 230                 235                 240

 Pro Phe Asn Asp Val Val Asp Lys Thr Pro Val Ile Arg Ser Val
                 245                 250                 255

 Ile Leu Lys Leu Leu Leu Lys Tyr Ser Phe His Asp Val Lys Asp
                 260                 265                 270

 Tyr Ile Gln Glu Tyr Leu Thr Leu Leu Lys Lys Lys Ala Phe Ile
                 275                 280                 285

 Thr Glu Asp Lys Thr Glu Leu Tyr Met Leu Phe Ile Asn Cys Leu
                 290                 295                 300

 Glu Asp Ser Ile Leu Glu Lys Thr Ser Ala Tyr Ser Arg Asn Asp
                 305                 310                 315

 Glu Leu Asn His Leu Glu Glu Glu Gly Arg Phe Leu Lys Ala Tyr
                 320                 325                 330

 Ser Pro Ala Ser Arg Gly Arg Glu Pro Ala Asn Glu Ala Ser Val
                 335                 340                 345

 Glu Tyr Leu Gln Glu Val Ala Arg Ile Arg Leu Cys Leu Asp Arg
                 350                 355                 360

 Ala Ala Asp Phe Leu Ser Glu Pro Glu Gly Gly Pro Glu Met Ala
                 365                 370                 375

 Lys Glu Lys Gln Cys Tyr Leu Gln Gln Val Lys Gln Phe Cys Ile
                 380                 385                 390

 Arg Val Glu Asn Asp Trp His Arg Val Tyr Leu Val Arg Lys Leu
                 395                 400                 405

 Ser Ser Gln Arg Gly Met Glu Phe Val Gln Gly Leu Ser Lys Pro
                 410                 415                 420

 Gly Arg Pro His Gln Trp Val Phe Pro Lys Asp Val Val Lys Gln
                 425                 430                 435

 Gln Gly Leu Arg Gln Asp His Pro Gly Gln Met Asp Arg Tyr Leu
                 440                 445                 450

 Val Tyr Gly Asp Glu Tyr Lys Ala Leu Arg Asp Ala Val Ala Lys
                 455                 460                 465

 Ala Val Leu Glu Cys Lys Pro Leu Gly Ile Lys Thr Ala Leu Lys
                 470                 475                 480

 Ala Cys Lys Thr Pro Gln Ser Gln Gln Ser Ala Tyr Phe Leu Leu
                 485                 490                 495

 Thr Leu Phe Arg Glu Val Ala Ile Leu Tyr Arg Ser His Asn Ala
                 500                 505                 510

 Ser Leu His Pro Thr Pro Glu Gln Cys Glu Ala Val Ser Lys Phe
                 515                 520                 525

 Ile Gly Glu Cys Lys Ile Leu Ser Pro Pro Asp Ile Ser Arg Phe
                 530                 535                 540

 Ala Thr Ser Leu Val Asp Asn Ser Val Pro Leu Leu Arg Ala Gly
                 545                 550                 555

 Pro Ser Asp Ser Asn Leu Asp Gly Thr Val Thr Glu Met Ala Ile
                 560                 565                 570

 His Ala Ala Ala Val Leu Leu Cys Gly Gln Asn Glu Leu Leu Glu
                 575                 580                 585

 Pro Leu Lys Asn Leu Ala Phe Ser Pro Ala Thr Met Ala His Ala
                 590                 595                 600

 Phe Leu Pro Thr Met Pro Glu Asp Leu Leu Ala Gln Ala Arg Arg
                 605                 610                 615

 Trp Lys Gly Leu Glu Arg Val His Trp Tyr Thr Cys Pro Asn Gly
                 620                 625                 630

 His Pro Cys Ser Val Gly Glu Cys Gly Arg Pro Met Glu Gln Ser
                 635                 640                 645

 Ile Cys Ile Asp Cys His Ala Pro Ile Gly Gly Ile Asp His Lys
                 650                 655                 660

 Pro Arg Asp Gly Phe His Leu Val Lys Asp Lys Ala Asp Arg Thr
                 665                 670                 675

 Gln Thr Gly His Val Leu Gly Asn Pro Gln Arg Arg Asp Val Val
                 680                 685                 690

 Thr Cys Asp Arg Gly Leu Pro Pro Val Val Phe Leu Leu Ile Arg
                 695                 700                 705

 Leu Leu Thr His Leu Ala Leu Leu Leu Gly Ala Ser Gln Ser Ser
                 710                 715                 720

 Gln Ala Leu Ile Asn Ile Ile Lys Pro Pro Val Arg Asp Pro Lys
                 725                 730                 735

 Gly Phe Leu Gln Gln His Ile Leu Lys Asp Leu Glu Gln Leu Ala
                 740                 745                 750

 Lys Met Leu Gly His Ser Ala Asp Glu Thr Ile Gly Val Val His
                 755                 760                 765

 Leu Val Leu Arg Arg Leu Leu Gln Glu Gln His Gln Leu Ser Ser
                 770                 775                 780

 Arg Arg Leu Leu Asn Phe Asp Thr Glu Leu Ser Thr Lys Glu Met
                 785                 790                 795

 Arg Asn Asn Trp Glu Lys Glu Ile Ala Ala Val Ile Ser Pro Glu
                 800                 805                 810

 Leu Glu His Leu Asp Lys Thr Leu Pro Thr Met Asn Asn Leu Ile
                 815                 820                 825

 Ser Gln Asp Lys Arg Ile Ser Ser Asn Pro Val Ala Lys Ile Ile
                 830                 835                 840

 Tyr Gly Asp Pro Val Thr Phe Leu Pro His Leu Pro Arg Lys Ser
                 845                 850                 855

 Val Val His Cys Ser Lys Ile Trp Ser Cys Arg Lys Arg Ile Thr
                 860                 865                 870

 Val Glu Tyr Leu Gln His Ile Val Glu Gln Lys Asn Gly Lys Glu
                 875                 880                 885

 Arg Val Pro Ile Leu Trp His Phe Leu Gln Lys Glu Ala Glu Leu
                 890                 895                 900

 Arg Leu Val Lys Phe Leu Pro Glu Ile Leu Ala Leu Gln Arg Asp
                 905                 910                 915

 Leu Val Lys Gln Phe Gln Asn Val Gln Gln Val Glu Tyr Ser Ser
                 920                 925                 930

 Ile Arg Gly Phe Leu Ser Lys His Ser Ser Asp Gly Leu Arg Gln
                 935                 940                 945

 Leu Leu His Asn Arg Ile Thr Val Phe Leu Ser Thr Trp Asn Lys
                 950                 955                 960

 Leu Arg Arg Ser Leu Glu Thr Asn Gly Glu Ile Asn Leu Pro Lys
                 965                 970                 975

 Asp Tyr Cys Ser Thr Asp Leu Asp Leu Asp Thr Glu Phe Glu Ile
                 980                 985                 990

 Leu Leu Pro Arg Arg Arg Gly Leu Gly Leu Cys Ala Thr Ala Leu
                 995                1000                1005

 Val Ser Tyr Leu Ile Arg Leu His Asn Glu Ile Val Tyr Ala Val
                1010                1015                1020

 Glu Lys Leu Ser Lys Glu Asn Asn Ser Tyr Ser Val Asp Ala Ala
                1025                1030                1035

 Glu Val Thr Glu Leu His Val Ile Ser Tyr Glu Val Glu Arg Asp
                1040                1045                1050

 Leu Thr Pro Leu Ile Leu Ser Asn Cys Gln Tyr Gln Val Glu Glu
                1055                1060                1065

 Gly Arg Glu Thr Val Gln Glu Phe Asp Leu Glu Lys Ile Gln Arg
                1070                1075                1080

 Gln Ile Val Ser Arg Phe Leu Gln Gly Lys Pro Arg Leu Ser Leu
                1085                1090                1095

 Lys Gly Ile Pro Thr Leu Val Tyr Arg His Asp Trp Asn Tyr Glu
                1100                1105                1110

 His Leu Phe Met Asp Ile Lys Asn Lys Met Ala Gln Asp Ser Leu
                1115                1120                1125

 Pro Ser Ser Val Ile Ser Ala Ile Ser Gly Gln Leu Gln Ser Tyr
                1130                1135                1140

 Ser Asp Ala Cys Glu Val Leu Ser Val Val Glu Val Thr Leu Gly
                1145                1150                1155

 Phe Leu Ser Thr Ala Gly Gly Asp Pro Asn Met Gln Leu Asn Val
                1160                1165                1170

 Tyr Thr Gln Asp Ile Leu Gln Met Gly Asp Gln Thr Ile His Val
                1175                1180                1185

 Leu Lys Ala Leu Asn Arg Cys Gln Leu Lys His Thr Ile Ala Leu
                1190                1195                1200

 Trp Gln Phe Leu Ser Ala His Lys Ser Glu Gln Leu Leu Arg Leu
                1205                1210                1215

 His Lys Glu Pro Phe Gly Glu Ile Ser Ser Arg Tyr Lys Ala Asp
                1220                1225                1230

 Leu Ser Pro Glu Asn Ala Lys Leu Leu Ser Thr Phe Leu Asn Gln
                1235                1240                1245

 Thr Gly Leu Asp Ala Phe Leu Leu Glu Leu His Glu Met Ile Ile
                1250                1255                1260

 Leu Lys Leu Lys Asn Pro Gln Thr Gln Thr Glu Glu Arg Phe Arg
                1265                1270                1275

 Pro Gln Trp Ser Leu Arg Asp Thr Leu Val Ser Tyr Met Gln Thr
                1280                1285                1290

 Lys Glu Ser Glu Ile Leu Pro Glu Met Ala Ser Gln Phe Pro Glu
                1295                1300                1305

 Glu Ile Leu Leu Ala Ser Cys Val Ser Val Trp Lys Thr Ala Ala
                1310                1315                1320

 Val Leu Lys Trp Asn Arg Glu Met Arg
                1325

<210> 4296
<211> 3577
<212> DNA
<213> Homo sapien

<400> 4296
 gaccattgtg aggacaatgt taatttaaaa taataacaat aatagcaaga 50

 agaagtcctg ccccatgaca agaaaatctg ctcccacctc agggctttta 100

 aattttgaca cagaattgtc aactaaagaa atgaggaaca actgggaaaa 150

 ggaaatcgca gctgtgattt ctcctgaact ggagcatcta gataaaaccc 200

 ttcccaccat gaataatctc atcagccaag ataagcgtat cagctctaac 250

 cctgtggcca aaataatata tggtgaccca gtgaccttcc tgccccacct 300

 gccccggaaa agtgtggtcc attgctctaa gatttggagc tgcaggaaaa 350

 gaattacagt tgagtacctc cagcacattg tggaacagaa aaatggcaaa 400

 gaaagagtgc ccatcctctg gcatttcctg cagaaggaag cagagctgag 450

 gctggtaaag ttcctgcctg agattttggc cttgcaaagg gatctagtga 500

 agcagttcca gaacgtccag caagttgaat acagctccat cagaggcttc 550

 ctcagcaagc acagctcaga tgggttgagg cagctgcttc acaacaggat 600

 cacagtcttt ctgtccacat ggaacaaact gaggagatcg cttgagacga 650

 acggtgagat caacctaccc aaagactact gcagcactga cttggatctg 700

 gacactgagt ttgagatcct cttgccacgc cgacggggcc tgggcctctg 750

 tgctaccgct ctcgtcagct acttgattcg cctacacaat gaaattgtct 800

 acgccgtgga aaaactctcc aaggaaaaca acagctattc cgtggatgcc 850

 gccgaggtca ctgaactgca tgtcatcagt tatgaagtgg agcgggacct 900

 gactccactg attctctcca actgccagta ccaggtggag gagggcagag 950

 agaccgtgca ggagttcgat ctggagaaga ttcagcggca gatcgtcagc 1000

 cgcttcctcc agggcaagcc ccggctgagc ctcaagggaa tacccactct 1050

 ggtgtacaga cacgactgga actatgaaca tctctttatg gacatcaaga 1100

 acaaaatggc acaggactcc ctccccagct cggtcattag tgccatcagt 1150

 ggacagctgc agtcctacag cgatgcctgt gaagtgctgt ctgtcgtaga 1200

 agtcactctg gggtttctga gcacagctgg tggggatcca aacatgcagc 1250

 tgaatgtgta tactcaagac atcctgcaaa tgggtgatca gacgattcac 1300

 gtgttaaagg ccttaaacag atgccagtta aaacacacca ttgccctctg 1350

 gcagttcctg tctgctcata agtctgaaca gctgctgcgg ctgcacaaag 1400

 agccatttgg ggaaatcagt tcaaggtaca aagcggatct gagcccggaa 1450

 aatgctaagc tcctcagcac attcctaaat cagactggcc tagacgcctt 1500

 cctgctagag ctgcacgaaa tgataatctt gaaactaaag aacccccaaa 1550

 cccaaaccga ggagcgcttc cgccctcagt ggagcctgag agacactctc 1600

 gtaagttaca tgcaaactaa agaaagtgaa attcttcctg aaatggcatc 1650

 tcagttccca gaagagatac tgctcgccag ctgtgtctca gtgtggaaaa 1700

 cagctgctgt gctgaaatgg aatcgagaaa tgagatagaa ttatttcctc 1750

 agctatcttt ggatgacttt ggagagaaga ctcctctctc ctcgtctgcg 1800

 gcgtggactt gatcatggac tggtgccttt gcattcagaa ggagagctgt 1850

 cagcgtagca ccgaattcaa gaccaaggcg tgctacctga gctgacagct 1900

 ttttgaaagc cgagctgttt ctgaaccatg tacatacatg ttctgaaact 1950

 ttctcatcat tttatgagta ctgttcattg agagatgaca atgaagatta 2000

 gatgaaattg gaaataaacc aacattgttt acattccagg agacttgtag 2050

 ctcagccaca cacgcagtaa tgacctgtgc ccgttcgcct ctggcactgc 2100

 ccacccctct tttttttttt cttctaattc tgtactcaca aaagagaatc 2150

 tcattttctt ctttcttcca ttcccttaaa ttctgagtac tgtacatata 2200

 tttctgggtt cccacgatga tgtgaaaaac taccagactg ttttttgtct 2250

 tctcacaaag acaagaaaaa tcagggcatt ttgtgagtgc cttaagatca 2300

 aactaacaag atctgaccct ctcccctcac agtgagccac tgccccactt 2350

 cagagggtaa gagccaaaag cctcattgtg aaaggcactg gacttggacc 2400

 agggacacca tcagggcctt ggttttctca cgcataaaat ggagagtgga 2450

 ttaatcgcca aagattcttc tgatctgaca ttttgaaatt gtgagagaaa 2500

 ctagatgact gtaaacttgg tcacaggcct ggttctggca gttctttgcg 2550

 gacttttttc tagcattatg ccaaataaac atgcagtctc agtgtgctct 2600

 cgcatgtatg aatatctagt cctttctgtg gttctcagcc aagacataaa 2650

 aactaggact cagagcacat acaaaaccag ttatgtttcg gaaagaggga 2700

 aaagagtccc cgagcccgga tcttgtgctg cttttctcac tgacgtgttg 2750

 ccttttttct ttacaaaatc tgctttgata cttaggacct ctctggacta 2800

 atttctcttc ctagacagct cagcacagct attgatatgt tagaggcagt 2850

 atccttaata ttcattctaa atgagttaac gacttaactt gaaattgggc 2900

 ctaaggagtg agaactacaa aaatacaaaa tgcttgtcca ggactcagcc 2950

 atgcacacct tgagcagcgc cggcaggagg cacggaagga actgtgctcc 3000

 gttctcctca ctgtcatggt gccaccagtg tctgatgaag ggcagagtga 3050

 cccagactgc aggcagtaac tgacttcaca cagtccctgg catttagtca 3100

 tctgtgattg ttttatcact ctggactgtg cagagccacc tgccaccgag 3150

 atctgcattc cgactgccta tgaacgggtg tgggggccgg gggctggctt 3200

 gctgaagtct tcaacttgca ctcggagctc ctttgatacc tcagagctgg 3250

 ctgtcaggtg gcagctcaca cccagactca ctggccacac ctcagcaggg 3300

 ggggagtcga gtgtcagtct ctttctgtga aggctttttt ttcctttggc 3350

 ctgggaattt ttcccatttt tatgaagggg ttttaaattg tttcattttg 3400

 tgtgctgtgc ttcaaagcct taactgtcaa atcttgcatt atcttgtttg 3450

 tacagaaata tactggccta gcagaggcaa aaaaaaaaaa atgaatttta 3500

 ttttacttgt cacacctgtc ttaataaact ggagttttgc tgctaaaaaa 3550

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 3577

<210> 4297
<211> 509
<212> PRT
<213> Homo sapien

<400> 4297
 Met Asn Asn Leu Ile Ser Gln Asp Lys Arg Ile Ser Ser Asn Pro
   1               5                  10                  15

 Val Ala Lys Ile Ile Tyr Gly Asp Pro Val Thr Phe Leu Pro His
                  20                  25                  30

 Leu Pro Arg Lys Ser Val Val His Cys Ser Lys Ile Trp Ser Cys
                  35                  40                  45

 Arg Lys Arg Ile Thr Val Glu Tyr Leu Gln His Ile Val Glu Gln
                  50                  55                  60

 Lys Asn Gly Lys Glu Arg Val Pro Ile Leu Trp His Phe Leu Gln
                  65                  70                  75

 Lys Glu Ala Glu Leu Arg Leu Val Lys Phe Leu Pro Glu Ile Leu
                  80                  85                  90

 Ala Leu Gln Arg Asp Leu Val Lys Gln Phe Gln Asn Val Gln Gln
                  95                 100                 105

 Val Glu Tyr Ser Ser Ile Arg Gly Phe Leu Ser Lys His Ser Ser
                 110                 115                 120

 Asp Gly Leu Arg Gln Leu Leu His Asn Arg Ile Thr Val Phe Leu
                 125                 130                 135

 Ser Thr Trp Asn Lys Leu Arg Arg Ser Leu Glu Thr Asn Gly Glu
                 140                 145                 150

 Ile Asn Leu Pro Lys Asp Tyr Cys Ser Thr Asp Leu Asp Leu Asp
                 155                 160                 165

 Thr Glu Phe Glu Ile Leu Leu Pro Arg Arg Arg Gly Leu Gly Leu
                 170                 175                 180

 Cys Ala Thr Ala Leu Val Ser Tyr Leu Ile Arg Leu His Asn Glu
                 185                 190                 195

 Ile Val Tyr Ala Val Glu Lys Leu Ser Lys Glu Asn Asn Ser Tyr
                 200                 205                 210

 Ser Val Asp Ala Ala Glu Val Thr Glu Leu His Val Ile Ser Tyr
                 215                 220                 225

 Glu Val Glu Arg Asp Leu Thr Pro Leu Ile Leu Ser Asn Cys Gln
                 230                 235                 240

 Tyr Gln Val Glu Glu Gly Arg Glu Thr Val Gln Glu Phe Asp Leu
                 245                 250                 255

 Glu Lys Ile Gln Arg Gln Ile Val Ser Arg Phe Leu Gln Gly Lys
                 260                 265                 270

 Pro Arg Leu Ser Leu Lys Gly Ile Pro Thr Leu Val Tyr Arg His
                 275                 280                 285

 Asp Trp Asn Tyr Glu His Leu Phe Met Asp Ile Lys Asn Lys Met
                 290                 295                 300

 Ala Gln Asp Ser Leu Pro Ser Ser Val Ile Ser Ala Ile Ser Gly
                 305                 310                 315

 Gln Leu Gln Ser Tyr Ser Asp Ala Cys Glu Val Leu Ser Val Val
                 320                 325                 330

 Glu Val Thr Leu Gly Phe Leu Ser Thr Ala Gly Gly Asp Pro Asn
                 335                 340                 345

 Met Gln Leu Asn Val Tyr Thr Gln Asp Ile Leu Gln Met Gly Asp
                 350                 355                 360

 Gln Thr Ile His Val Leu Lys Ala Leu Asn Arg Cys Gln Leu Lys
                 365                 370                 375

 His Thr Ile Ala Leu Trp Gln Phe Leu Ser Ala His Lys Ser Glu
                 380                 385                 390

 Gln Leu Leu Arg Leu His Lys Glu Pro Phe Gly Glu Ile Ser Ser
                 395                 400                 405

 Arg Tyr Lys Ala Asp Leu Ser Pro Glu Asn Ala Lys Leu Leu Ser
                 410                 415                 420

 Thr Phe Leu Asn Gln Thr Gly Leu Asp Ala Phe Leu Leu Glu Leu
                 425                 430                 435

 His Glu Met Ile Ile Leu Lys Leu Lys Asn Pro Gln Thr Gln Thr
                 440                 445                 450

 Glu Glu Arg Phe Arg Pro Gln Trp Ser Leu Arg Asp Thr Leu Val
                 455                 460                 465

 Ser Tyr Met Gln Thr Lys Glu Ser Glu Ile Leu Pro Glu Met Ala
                 470                 475                 480

 Ser Gln Phe Pro Glu Glu Ile Leu Leu Ala Ser Cys Val Ser Val
                 485                 490                 495

 Trp Lys Thr Ala Ala Val Leu Lys Trp Asn Arg Glu Met Arg
                 500                 505

<210> 4298
<211> 5349
<212> DNA
<213> Homo sapien

<400> 4298
 gttaaaagta gcagggccca gatatgcctt gggactccag tgtgagcctc 50

 gtccttgttt ccagctggaa ggaaggcacc ctcttgccca agacaggaca 100

 ctgtgctgcc tggggccagc acctgctgaa tcctcgagcc cagagcttct 150

 tcctgacact caggcctttc aaagcctgac tctcagggcc actgctgcac 200

 agggtgacaa ccgggcatgg cacgcagtgt ggctggtgca gaggaggctt 250

 aaggctggcc tgggagagat tcttggtcta gctcccagca cggagccttg 300

 cttgtgtccc agggcggcac taaccagaac cagaaaagga aatctttggc 350

 cctcggggag aattatgcca attatctgtc tggttcctgt ctttgaaaat 400

 gcccagatgt tggtttacaa atcaggaagc tgtcttgggg caatctctgt 450

 tccctctttg atgcagagag cctttctctg taaacactgg agagcagggc 500

 ttcactgtct ggctcccctc ccgcctcttg caggaaggac tagatgctgc 550

 tgatcagctg atcatggctg agccgggtag agcttggggc tctcctaaga 600

 ggtcacccac tgggagggag cttcacagct gttcttttga cccaggaagg 650

 agctctttca ggactgtggc acccagagcc gtggccctcc tgccatgcca 700

 ttgttcccac ttccctgccc ttgggagtct tggagacagc tgactagctg 750

 ccctgagggg tccaccgctc tcaccttctc actggtggct gctgccattc 800

 tcctgggctc tgcacagaaa gctttggtcc ttctgaaagc cactctgccc 850

 cttcctgcag caccagatcc ccctgagccg gtactgctgc ctccacctgg 900

 gccaagacta gtcttggtgt tcacccttct tcgtgcttca gaaagtaggg 950

 atatctgggg acatgactgt gtttccctgg ggtcctttca gaagagactt 1000

 aggaagctcc tgctcaggaa tctggccctc tgaaagagcc ccttcaaagc 1050

 agcctgggca gcaggtaacg tggtttccct tgcggccccc tcctcccagc 1100

 tgcatagact cgtggtttga agtgaacaga tcttgtccgg aacaccctgc 1150

 ggactgacct gcgggcttgc ttgctgactc ctctcaaagg tgagcccgcg 1200

 tttgggggtg ctccgggctc aaggcttggg gtcaggtcac tttgggggcc 1250

 tgcagtttag ggagccgggc tgcccttatg ccactgagaa gaaagcagga 1300

 gcagagggaa ggagcacctc atcagtgagc agttagtcat ccggaaatga 1350

 ttttccctgg gaaggacaag agatacaaac caacatggac agttatgaag 1400

 aacaggctca gaagagttag gatcagttgg ggaagagacc agtacaatct 1450

 acattcctaa agaaagttca ggaatatccc ctgggaatgt gcacgggcag 1500

 gaaaaggagc ctgagcggtg ggtttgtgcc tggcttggcc tcatcctcgc 1550

 tcacctctga gtctccgcct cttctatggt aacggggata atctcactcc 1600

 ctgttgccat aaggacattg cacttactaa acagccatgg gcagtgcatt 1650

 gttccctgca aagtgctggt cagcgatcat ttgaccactg cttcttccca 1700

 tgccgcttcc agatgaatct gaggcctcca ggccagactc gatccctcta 1750

 tcccacagca ctgggtgctg actccacaca tccccctggc ttaccgctgg 1800

 gtctggcctc cccatttctc ccccaggggt accccacttg ctgccaacca 1850

 tccacccctg acccccatct cacctgtccc ctccaagttc tgggctggca 1900

 ttttcctttt tctggcaaac aagtagacaa aacccccata aaaaccaaaa 1950

 gcccaactcc atctcacagc caaaggtttt gggacctttt tcttcccccc 2000

 tccctttctc tctctcttgc tttcgttttc ttttgttagg tttattttat 2050

 ttattccaag taaactccca gaacagctga tgatgtcaga caaatcaggg 2100

 acatttgctc tttttacctc cacctcaaaa actgatgaca aggggagaag 2150

 aaagagccag gggggagagt gaggcagggg agtagaacct gcccaggcac 2200

 atggctgcaa attccccgtg tgctgtttgg cttctggggt cctgtgtaga 2250

 cgccccagcc ccgcctgccc tcttgggatg cagctgccct gggatgagca 2300

 gacagccctc ggcccgatgg agcacgactt atttattacg gtccacacag 2350

 ggacagagcg cccctgctcc agggaggagg ctcaccggac cctggggcag 2400

 agctgagctt gggacaccag cgggaacagg gcaccccttc tgcactgact 2450

 tccagatcat ggttctccct tcctccctga ggacaccaaa ttggatgaga 2500

 gcaagtttga gagaagaatg aatcaactgc tatccttccc ctcacccctc 2550

 agcccaggag ggaaagggca ttttcttttt catctttgaa aggcattgtg 2600

 ggtctgtctt taaagtgttt acaaaaaaaa attatataaa aaaaaagtct 2650

 agtgtcgact ggtgttttcc ctcgtgatgt ttacagcttg ctgtttgctg 2700

 cccagccata acccactcag tgacagacga acacagctaa ggcctcgctg 2750

 ccagccttct gacggcgggc gagcacacgg tctcttcccc tgccccaact 2800

 ggccctctcc accaccaact tctctacttt gggtttgttt ggttttttcc 2850

 ctctattttt ctggctggtt ttttgctctt ttctcccctt gagaccctaa 2900

 tatcttgact tcattgccaa aaaacaaccc attgagaact ttcttcctac 2950

 tgatcccatc tcttttccct tctttcctcc tggttccggt cagttcagag 3000

 gatttaacaa tcacaagtgt cctgcaaaaa tgcctgaaca ttattcttag 3050

 gccctcgtgg attttttttt tcagaaaact taaacaaaaa aagacttact 3100

 aagaaatatg tacagctacc cctgttttca ggcactatgt ttgagaacat 3150

 tttagccatt gatgttcaca cgtggcatca gcccatgcaa gataggtttc 3200

 tgtatttata tattaaaata caaaaaaaaa cttataaaat gtttaaaaaa 3250

 atgttcaaag cttgggagaa aagctttctt cattagtcaa ggtgttttga 3300

 tatggtatta aaatgtctaa taaaagatgg cactgcgtga ttttatttta 3350

 atgaagtgtt atacaatcaa gaaatggggg caagggcctg ccccccactc 3400

 cctcacctac ctccttagca ttccttcagg ctgctactcg gggctccagg 3450

 tgtgtgaatt ggtcctcaga tagtcaggcc tgggtggagg gagtggcaag 3500

 tcaggcgtgc ctcctacaag cttcctaacc tcttaagcat catggaacca 3550

 gtcagccctc tgtggagtca ttgtgccgga cctctgaaaa gatctgcagg 3600

 ggccaagatg ttgcagccac cggaggctgc aaggatgtgg gttcttccag 3650

 gtgtgggccc agcccccctc cttccagcct ttgctcccca tcccacgttc 3700

 cactcgccct gcctgttgtt cagtttgcgt ctcagtgctg actcacgggc 3750

 atgcttcatt gaggcccagg aagaggccct ggtttggggc tgtgccagct 3800

 cagagccctt gaaccagaac caactgctca ggctcacaaa agttggcaaa 3850

 atgcgggctg ggcaggcagc tcggggcagg gagcagcagt gcaggcctgg 3900

 cctgtgtccc cgtgcccagc gggctcccgg agcagcattc cagagcctcc 3950

 tgcagagcca gcgaaggaaa gctctagagg gagacgactc caccgcctct 4000

 ctgctctgac ccttctcagg cccgcctgat gtgctggacc atccccctgc 4050

 tgccacggcc cctggctccg cagtcaccct ccatcagatg cttccagaag 4100

 cacctactct gtgcaagggc attcacaaca ggccagtggg caaacgtgag 4150

 ccagggccag cggagaaaca ctaaagaaga ctcggtggtt cagagcctgg 4200

 gtctcagcgc gggacccgtc tggggtgaag accttggggc tgttgtgagt 4250

 cggtggcagg aacgtgggct ctagactgtg cattcaggct ctcctacttg 4300

 gcagaatgat cttggggaaa cgacttcatc tgaacttcag atatttcaca 4350

 tgtgaagcgg ggacaaaacc atgcagctca gaggtccctg tgggggctgg 4400

 gggagctgcc ctgcaggtct tggcacatgc acagcaggct ccccatagct 4450

 ttgtcaccac aaagggcact gttctattca cagcacctcc tgcttctgcc 4500

 tggcaactgt gtctccctgt gctatattta attccaccag caaagctggc 4550

 gaggcagggc ccagccctga aggagatctc cttgcctgac ccctggacct 4600

 ggaaatggag gcttcatgtg cccgccttgg cggcttaagc ctgctgcttt 4650

 ggcagtgcca tgggtgagcc gagcagctgt gaggtgggtg gggcagggct 4700

 gtagcccacg ccgggtgcta ttccaggctc taggggctgg tgctcatccc 4750

 cacccccagc gacttccgtc ctacctggca tgctgcagcc ctctgccggc 4800

 tgtggtgtcc tctgaatttg gacccaggtt gcctgctctt gttgtggggg 4850

 tgggattggg gctgtctgtg tttcccaggt ggagctcatg tttgtgatcc 4900

 tctatctgga cagctctcca gaatcctgtg ttgcccctgt tctgcctttc 4950

 tgggatggga gagaaggtga gggagccggc gagccggttc taccctctct 5000

 gctaagggcc tagcacgctt tgatgaggtt cctggacgtg agaccctcac 5050

 aaagaccaac cattcctcta atagccattt aacggtactg cagttcatgg 5100

 gaaaatgtcc tcattcttag gagatagatg ctggattata taggtgaatg 5150

 ccttcaagaa atgtgtaatt taattccaaa tagttccccc caaaatacac 5200

 aaagcaaata aggccaaaat gttcattgtt gaatctgcag tggctggtat 5250

 ttcagtgaac agtgtacttg ttctttcaac ttttctgtat gtttggaatt 5300

 tttcttaata aaagattgtg ggaaatggtc aaaaaaaaaa aaaaaaaaa 5349

<210> 4299
<211> 183
<212> PRT
<213> Homo sapien

<400> 4299
 Leu Lys Val Ala Gly Pro Arg Tyr Ala Leu Gly Leu Gln Cys Glu
   1               5                  10                  15

 Pro Arg Pro Cys Phe Gln Leu Glu Gly Arg His Pro Leu Ala Gln
                  20                  25                  30

 Asp Arg Thr Leu Cys Cys Leu Gly Pro Ala Pro Ala Glu Ser Ser
                  35                  40                  45

 Ser Pro Glu Leu Leu Pro Asp Thr Gln Ala Phe Gln Ser Leu Thr
                  50                  55                  60

 Leu Arg Ala Thr Ala Ala Gln Gly Asp Asn Arg Ala Trp His Ala
                  65                  70                  75

 Val Trp Leu Val Gln Arg Arg Leu Lys Ala Gly Leu Gly Glu Ile
                  80                  85                  90

 Leu Gly Leu Ala Pro Ser Thr Glu Pro Cys Leu Cys Pro Arg Ala
                  95                 100                 105

 Ala Leu Thr Arg Thr Arg Lys Gly Asn Leu Trp Pro Ser Gly Arg
                 110                 115                 120

 Ile Met Pro Ile Ile Cys Leu Val Pro Val Phe Glu Asn Ala Gln
                 125                 130                 135

 Met Leu Val Tyr Lys Ser Gly Ser Cys Leu Gly Ala Ile Ser Val
                 140                 145                 150

 Pro Ser Leu Met Gln Arg Ala Phe Leu Cys Lys His Trp Arg Ala
                 155                 160                 165

 Gly Leu His Cys Leu Ala Pro Leu Pro Pro Leu Ala Gly Arg Thr
                 170                 175                 180

 Arg Cys Cys


<210> 4300
<211> 1668
<212> DNA
<213> Homo sapien

<400> 4300
 gcaggatttg accgagtctt tatcggggct tccgttacat cttattctaa 50

 ctcaggttta cggacacaat gctggaaaac caattcctgc tctacccacc 100

 cctcaacttg ttaaaaaaaa acaggatcta acaccgagga atgtcacatc 150

 ttcgccattc ccacttcctt tctgccctag gcattcgata tgtgccacca 200

 ggggccatca ggactagggc tctgcaccca tggcagcaga caggtgtgaa 250

 gctcagagtc cctcctaaca gcctccctcc agcgtcttct tggcgcgttt 300

 tacaaggcgc ttttttgcac acatctccca tcctttctga ggttggtgcc 350

 agtcccgctt tacaaacatg cagggacaag cccaggacgg ccgaggtttc 400

 gcgggctcgt cgatggctcg gtgattttgt cagccggcgt ctaaagcacg 450

 cggcaggcgc tcaaaccttg aaccaacggg aaagcaaagg aaagccgggg 500

 cccgctggct cttggagggg aagggctggg aaggggggaa ggggcccgcg 550

 cccacctacc gcagcggcga agccagctcc gcagggcctc ggaactcccg 600

 cgcgcagaag tccattactc aggcggccgc ccggggccgt ggaggcctgc 650

 acgcacctgc cgtacgccgc ggcctcggcc ccgcaggcgg ccagccgctc 700

 ggggaaggcg cggaggcggc ttcgcacgcg gccccacacc gctccgttag 750

 ccgacatgag cggctattcc cagcccccta gaggccgcca tcttaggtcc 800

 gttacatctt attctaactc aggtttacgg acacaatgct ggaaaaccaa 850

 ttcctgctct acccacgcct caacttgtta agaaaaaaca ggatctaaca 900

 ccgaggaatg tcacatcttc gccattccca cttcctttct gccctaggca 950

 ttcgatatgt gccaccaggg gccatcagga ctagggctct gcacccatgg 1000

 cagcagacag gtgtgaagct cagagtccct cctaacagcc tccagggggc 1050

 tgggaatagc cgctcatgtc ggctaacgga gcggtgtggg gccgcgtgcg 1100

 aagccgcctc cgcgccttcc ccgagcggct ggccgcctgc ggggccgagg 1150

 ccgcggcgta cggcaggtgc gtgcaggcct ccacggcccc gggcggccgc 1200

 ctgagtaagg acttctgcgc gcgggagttc gaggccctgc ggagctgctt 1250

 cgccgctgcg gccaagaaga cgctggaggg aggctgttag gagggactct 1300

 gagcttcaca cctgtctgct gccatgggtg cagagcccta gtcctgatgg 1350

 cccctggtgg cacatatcga atgcctaggg cagaaaggaa gtgggaatgg 1400

 cgaagatgtg acattcctcg gtgttagatc ctgttttttc ttaacaagtt 1450

 gaggcgtggg tagagcagga attggttttc cagcattgtg tccgtaaacc 1500

 tgagttagaa taagatgtaa cggaagccac gataaagact cggtcaaatc 1550

 ctgcaaaata aaatatctct ttatccccta tttcttatat catatcatcc 1600

 tcctcctctc tcccctcctt tcaacatata aaattaactg gcccgcgttt 1650

 accaacgtgg caactggt 1668

<210> 4301
<211> 246
<212> PRT
<213> Homo sapien

<400> 4301
 Met Ser His Leu Arg His Ser His Phe Leu Ser Ala Leu Gly Ile
   1               5                  10                  15

 Arg Tyr Val Pro Pro Gly Ala Ile Arg Thr Arg Ala Leu His Pro
                  20                  25                  30

 Trp Gln Gln Thr Gly Val Lys Leu Arg Val Pro Pro Asn Ser Leu
                  35                  40                  45

 Pro Pro Ala Ser Ser Trp Arg Val Leu Gln Gly Ala Phe Leu His
                  50                  55                  60

 Thr Ser Pro Ile Leu Ser Glu Val Gly Ala Ser Pro Ala Leu Gln
                  65                  70                  75

 Thr Cys Arg Asp Lys Pro Arg Thr Ala Glu Val Ser Arg Ala Arg
                  80                  85                  90

 Arg Trp Leu Gly Asp Phe Val Ser Arg Arg Leu Lys His Ala Ala
                  95                 100                 105

 Gly Ala Gln Thr Leu Asn Gln Arg Glu Ser Lys Gly Lys Pro Gly
                 110                 115                 120

 Pro Ala Gly Ser Trp Arg Gly Arg Ala Gly Lys Gly Gly Arg Gly
                 125                 130                 135

 Pro Arg Pro Pro Thr Ala Ala Ala Lys Pro Ala Pro Gln Gly Leu
                 140                 145                 150

 Gly Thr Pro Ala Arg Arg Ser Pro Leu Leu Arg Arg Pro Pro Gly
                 155                 160                 165

 Ala Val Glu Ala Cys Thr His Leu Pro Tyr Ala Ala Ala Ser Ala
                 170                 175                 180

 Pro Gln Ala Ala Ser Arg Ser Gly Lys Ala Arg Arg Arg Leu Arg
                 185                 190                 195

 Thr Arg Pro His Thr Ala Pro Leu Ala Asp Met Ser Gly Tyr Ser
                 200                 205                 210

 Gln Pro Pro Arg Gly Arg His Leu Arg Ser Val Thr Ser Tyr Ser
                 215                 220                 225

 Asn Ser Gly Leu Arg Thr Gln Cys Trp Lys Thr Asn Ser Cys Ser
                 230                 235                 240

 Thr His Ala Ser Thr Cys
                 245

<210> 4302
<211> 5088
<212> DNA
<213> Homo sapien

<400> 4302
 agcggagttc ctggagaaag atggcgacag ccgagaagca gaaacacgac 50

 gggcgggtga agatcggcca ctacattctg ggtgacacgc tgggggtcgg 100

 caccttcggc aaagtgaagg ttggcaaaca tgaattgact gggcataaag 150

 tagctgtgaa gatactcaat cgacagaaga ttcggagcct tgatgtggta 200

 ggaaaaatcc gcagagaaat tcagaacctc aagcttttca ggcatcctca 250

 tataattaaa ctgtaccagg tcatcagtac accatctgat attttcatgg 300

 tgatggaata tgtctcagga ggagagctat ttgattatat ctgtaagaat 350

 ggaaggctgg atgaaaaaga aagtcggcgt ctgttccaac agatcctttc 400

 tggtgtggat tattgtcaca ggcatatggt ggtccataga gatttgaaac 450

 ctgaaaatgt cctgcttgat gcacacatga atgcaaagat agctgatttt 500

 ggtctttcaa acatgatgtc agatggtgaa tttttaagaa caagttgtgg 550

 ctcacccaac tatgctgcac cagaagtaat ttcaggaaga ttgtatgcag 600

 gcccagaggt agatatatgg agcagtgggg ttattctcta tgctttatta 650

 tgtggaaccc ttccatttga tgatgaccat gtgccaactc tttttaagaa 700

 gatatgtgat gggatcttct atacccctca atatttaaat ccttctgtga 750

 ttagcctttt gaaacatatg ctgcaggtgg atcccatgaa gagggccaca 800

 atcaaagata tcagggaaca tgaatggttt aaacaggacc ttccaaaata 850

 tctctttcct gaggatccat catatagttc aaccatgatt gatgatgaag 900

 ccttaaaaga agtatgtgaa aagtttgagt gctcagaaga ggaagttctc 950

 agctgtcttt acaacagaaa tcaccaggat cctttggcag ttgcctacca 1000

 tctcataata gataacagga gaataatgaa tgaagccaaa gatttctatt 1050

 tggcgacaag cccacctgat tcttttcttg atgatcatca cctgactcgg 1100

 ccccatcctg aaagagtacc attcttggtt gctgaaacac caagggcacg 1150

 ccataccctt gatgaattaa atccacagaa atccaaacac caaggtgtaa 1200

 ggaaagcaaa atggcattta ggaattagaa gtcaaagtcg accaaatgat 1250

 attatggcag aagtatgtag agcaatcaaa caattggatt atgaatggaa 1300

 ggttgtaaac ccatattatt tgcgtgtacg aaggaagaat cctgtgacaa 1350

 gcacttactc caaaatgagt ctacagttat accaagtgga tagtagaact 1400

 tatctactgg atttccgtag tattgatgat gaaattacag aagccaaatc 1450

 agggactgct actccacaga gatcgggatc agttagcaac tatcgatctt 1500

 gccaaaggag tgattcagat gctgaggctc aaggaaaatc ctcagaagtt 1550

 tctcttacct catctgtgac ctcacttgac tcttctcctg ttgacctaac 1600

 tccaagacct ggaagtcaca caatagaatt ttttgagatg tgtgcaaatc 1650

 taattaaaat tcttgcacaa taaacagaaa actttgctta tttcttttgc 1700

 agcaataagc atgcataata agtcacagcc aaatgcttcc atttgtaatc 1750

 aagttataca taattataac cgagggctgg cgttttggaa tgcaatttgc 1800

 acagggattg gaacatgatt tatagttaaa agcctaatat gcagaaatga 1850

 attaagatca ttttgttgtt cattgtgcag tatgtatata gcataatata 1900

 cacagtgaat tataggtctc aggcttactt gatttttggc tattttatat 1950

 ttagtgtaca cagggctttg aaatattaat ttacataaag gccttcatat 2000

 attattacgt gttatatatt acgtgttata aatttattca ataaatattt 2050

 gcctagaatt cccaagacct ttataggtga ttttgttttc tgggctcctt 2100

 aacttcataa atagctagta tcttccagca gtagtaacag tctggataac 2150

 ttcttccata tccctccctc tttgtttttt tgagacagtg tcactttgtc 2200

 acccaggctg gagtgcaatg gtgtggtctc ggctcactgc aacctccacc 2250

 tcccgggttc gagtgattct cccgcctcag cttcctgagt agctggaact 2300

 acaggcgtgt gccaccacac ccggctaatt tttcgtattt ttagtgtaga 2350

 cggggtttca ctatgttgcc caggctggtc tcgaactcct gaccgcgtga 2400

 tccaccacct cagcttccca aagtggtggg attacaggcg tgagccaccg 2450

 cacccggcct ccatatcccc cttttaaaat tctgtagtgt atggtaagtc 2500

 atatcagata tcagacctaa tttaaatttc attttagctt tacaagtcca 2550

 aaaacacaga atttatatat tcagatactc tagcactaat tttagtctta 2600

 aaatattccc acgatattct gtacacaaaa tgttcttttt gttacaagag 2650

 ctgagttgca tatactgtag ataaatcata ttatttttgc caatttcaca 2700

 aattcctctg gcccatcatg tcagtcatta ttgagtatat gcacacattg 2750

 ctacttattt gattatgtat cttttaaatt gattcagtgc atagaaaact 2800

 atctcttaca aactttaagt gctctgatat gacttccccc ccaaatttta 2850

 ttatgaacat ttttaaaaac agaaaaattg aaaaactgtt tggtaagcac 2900

 atgtatatct accatttaga ttcagcagtt gttaatgttt tgtcatttgt 2950

 tttctctata cctatatatg tatagataca gctagttatg catatatatg 3000

 catatatgtg tttgtttgtg tatgtatata tgcttttttc cccctgaacc 3050

 atttggatgt tacagacata cttatcaccg tgaaaatact tcaagtatct 3100

 cctacagata atgacattct cctaaaaatc cgtaatacca ttgtaaaagt 3150

 aataattccc caatatcatc taatcaagcc atatttaaat ttctgaagtt 3200

 aactccaaat ttctttatag ctgattattt caaactagga tccaattaaa 3250

 gtttacatat gacacttggt tataactctt tagttggata taacattatt 3300

 attattttga taaaatatgg aacaaatcaa ttctattaat aagtggtcac 3350

 atttgttttg ggcttaaatt actttttaaa gatactggat tttcctaaga 3400

 tttctgattt acactgatat ttttttttgt cattcttaat tgcatcacac 3450

 aatagatgta aatgaagatg tagtcacctc agataaaatt ggtatcgtgt 3500

 atgataatat tgtatcattt atatttgcct tatgttaact ttaagaaatt 3550

 gatttttttg tattaatcat tttcccattg caacagagct atattttttc 3600

 tattttaaga atcatatttt aggattattt ttggcaaata cagtgagcac 3650

 ttatgtaacc agatgataat gaactcaaat gtcatgatag cttgcataaa 3700

 tggtgactct agtagatttg actcaagcac ttctagaatc atgcactgaa 3750

 ttcaaaggaa aaatcttgct gctttttgtc cagggcttgt tctattcaac 3800

 ttctaatttg aaagctgtac aaagtaatag aagttccatt taaatatgag 3850

 ttcaaaactg tatttacttt ttatgtggcc ctctctttag gggattctaa 3900

 ttttacttag ggtctctaag tgcagcataa tgttcctgat gttaacagaa 3950

 gactgtattt ttaaagttac aaatttgtat atggaattaa gtaatggcgc 4000

 tatatacgct gttgtgggga ggggggaaga aaaggaggaa ccaattaaat 4050

 aggacctttt aaaaattgtt aattttgtaa actttgcttc tcttataagt 4100

 tattgtgatt cattttagtt actgtgtttt attttgaaaa tatttaaata 4150

 ttgcacttct ataaatagta tgataaatgc acagacaatt gcagtaaatt 4200

 cttttttaag ctaggatatt tgaaatgaca acctttggtt aagtgtgtca 4250

 aggttgcaac agaattttca caattttttt gttgtttgca aattgttact 4300

 aatattgaag aggtaaggga ggcaatgcaa atgattttta atcttttttt 4350

 attatctttt cagcagttta tattttttgt gactttatgc aaccatattt 4400

 ttactttgtc ttgacaactg aaagatgtat aaggtttttt gccagaaatg 4450

 tactgtatac atagttttaa gtataacaga ttttactgat atgtaaaaat 4500

 tttgccatta aaataaatga tttctcactg agaggaactt ttctaccagg 4550

 ttggggcata tgggagctta atatatcata tctaatttaa aataatttca 4600

 ctgaaataaa ctccattgct tttacctaat ttttttcttg agatgctttt 4650

 gtagtttttc agagttttag atgattttat acaaaatcct ctgcctagca 4700

 ctgctctttt tgatgttgta gtgacaccat ttacattgaa ttaatgcttg 4750

 gtagcctggg gctagatgtg gaactccatg gatctgtgtt ctgactggca 4800

 cctttggaat gaaagaaaag tgtgtgctgt ccaaattttt tccccttaat 4850

 tctttccctc atcttctcac ccataataga aattttattt ccattgtgag 4900

 ttctgacaag aatgaaattc cacatacaac ataactgtaa attgttggta 4950

 ggtagaagtt aatatttgtg gttcatgtat attttgacca gagtatattt 5000

 aagtatataa tttcagcttc cttgatttag aaatatgata taataaagaa 5050

 aaactccatt tatcatctgt taaaaaaaaa aaaaaaaa 5088

<210> 4303
<211> 550
<212> PRT
<213> Homo sapien

<400> 4303
 Met Ala Thr Ala Glu Lys Gln Lys His Asp Gly Arg Val Lys Ile
   1               5                  10                  15

 Gly His Tyr Ile Leu Gly Asp Thr Leu Gly Val Gly Thr Phe Gly
                  20                  25                  30

 Lys Val Lys Val Gly Lys His Glu Leu Thr Gly His Lys Val Ala
                  35                  40                  45

 Val Lys Ile Leu Asn Arg Gln Lys Ile Arg Ser Leu Asp Val Val
                  50                  55                  60

 Gly Lys Ile Arg Arg Glu Ile Gln Asn Leu Lys Leu Phe Arg His
                  65                  70                  75

 Pro His Ile Ile Lys Leu Tyr Gln Val Ile Ser Thr Pro Ser Asp
                  80                  85                  90

 Ile Phe Met Val Met Glu Tyr Val Ser Gly Gly Glu Leu Phe Asp
                  95                 100                 105

 Tyr Ile Cys Lys Asn Gly Arg Leu Asp Glu Lys Glu Ser Arg Arg
                 110                 115                 120

 Leu Phe Gln Gln Ile Leu Ser Gly Val Asp Tyr Cys His Arg His
                 125                 130                 135

 Met Val Val His Arg Asp Leu Lys Pro Glu Asn Val Leu Leu Asp
                 140                 145                 150

 Ala His Met Asn Ala Lys Ile Ala Asp Phe Gly Leu Ser Asn Met
                 155                 160                 165

 Met Ser Asp Gly Glu Phe Leu Arg Thr Ser Cys Gly Ser Pro Asn
                 170                 175                 180

 Tyr Ala Ala Pro Glu Val Ile Ser Gly Arg Leu Tyr Ala Gly Pro
                 185                 190                 195

 Glu Val Asp Ile Trp Ser Ser Gly Val Ile Leu Tyr Ala Leu Leu
                 200                 205                 210

 Cys Gly Thr Leu Pro Phe Asp Asp Asp His Val Pro Thr Leu Phe
                 215                 220                 225

 Lys Lys Ile Cys Asp Gly Ile Phe Tyr Thr Pro Gln Tyr Leu Asn
                 230                 235                 240

 Pro Ser Val Ile Ser Leu Leu Lys His Met Leu Gln Val Asp Pro
                 245                 250                 255

 Met Lys Arg Ala Thr Ile Lys Asp Ile Arg Glu His Glu Trp Phe
                 260                 265                 270

 Lys Gln Asp Leu Pro Lys Tyr Leu Phe Pro Glu Asp Pro Ser Tyr
                 275                 280                 285

 Ser Ser Thr Met Ile Asp Asp Glu Ala Leu Lys Glu Val Cys Glu
                 290                 295                 300

 Lys Phe Glu Cys Ser Glu Glu Glu Val Leu Ser Cys Leu Tyr Asn
                 305                 310                 315

 Arg Asn His Gln Asp Pro Leu Ala Val Ala Tyr His Leu Ile Ile
                 320                 325                 330

 Asp Asn Arg Arg Ile Met Asn Glu Ala Lys Asp Phe Tyr Leu Ala
                 335                 340                 345

 Thr Ser Pro Pro Asp Ser Phe Leu Asp Asp His His Leu Thr Arg
                 350                 355                 360

 Pro His Pro Glu Arg Val Pro Phe Leu Val Ala Glu Thr Pro Arg
                 365                 370                 375

 Ala Arg His Thr Leu Asp Glu Leu Asn Pro Gln Lys Ser Lys His
                 380                 385                 390

 Gln Gly Val Arg Lys Ala Lys Trp His Leu Gly Ile Arg Ser Gln
                 395                 400                 405

 Ser Arg Pro Asn Asp Ile Met Ala Glu Val Cys Arg Ala Ile Lys
                 410                 415                 420

 Gln Leu Asp Tyr Glu Trp Lys Val Val Asn Pro Tyr Tyr Leu Arg
                 425                 430                 435

 Val Arg Arg Lys Asn Pro Val Thr Ser Thr Tyr Ser Lys Met Ser
                 440                 445                 450

 Leu Gln Leu Tyr Gln Val Asp Ser Arg Thr Tyr Leu Leu Asp Phe
                 455                 460                 465

 Arg Ser Ile Asp Asp Glu Ile Thr Glu Ala Lys Ser Gly Thr Ala
                 470                 475                 480

 Thr Pro Gln Arg Ser Gly Ser Val Ser Asn Tyr Arg Ser Cys Gln
                 485                 490                 495

 Arg Ser Asp Ser Asp Ala Glu Ala Gln Gly Lys Ser Ser Glu Val
                 500                 505                 510

 Ser Leu Thr Ser Ser Val Thr Ser Leu Asp Ser Ser Pro Val Asp
                 515                 520                 525

 Leu Thr Pro Arg Pro Gly Ser His Thr Ile Glu Phe Phe Glu Met
                 530                 535                 540

 Cys Ala Asn Leu Ile Lys Ile Leu Ala Gln
                 545                 550

<210> 4304
<211> 3941
<212> DNA
<213> Homo sapien

<400> 4304
 gcaggatgtg atggaaatga aaaaaacaaa ggttcgccta atgaaacaaa 50

 tgaaagaaga acaagagaaa gccagactga ctgagtctag aagaaacaga 100

 gagattgctc agttgaaaaa ggatcaacgt aaaagagatc atcaacttag 150

 acttctggaa gcccaaaaaa gaaaccaaga agtggttcta cgtcgcaaaa 200

 ctgaagaggt tacggctctt cgtcggcaag taagacccat gtcagataaa 250

 gtggctggga aagttactcg gaagctgagt tcatctgatg cacctgctca 300

 ggacacaggt tccagtgcag ctgctgtcga aacagatgca tcaaggacag 350

 gagcccagca gaaaatgaga attcctgtgg cgagagtcca ggccttacca 400

 acgccggcaa caaatggaaa caggaaaaaa tatcagagga aaggattgac 450

 tggccgagtg tttatttcca agacagctcg catgaagtgg cagctccttg 500

 agcgcagggt cacagacatc atcatgcaga agatgaccat ttccaacatg 550

 gaggcagata tgaatagact cctcaagcaa cgggaggaac tcacaaaaag 600

 acgagagaaa ctttcaaaaa gaagggagaa gatagtcaag gagaatggag 650

 agggagataa aaatgtggct aatatcaatg aagagatgga gtcactgact 700

 gctaatatcg attacatcaa tgacagtatt tctgattgtc aggccaacat 750

 aatgcagatg gaagaagcaa aggaagaagg tgagacattg gatgttactg 800

 cagtcattaa tgcctgcacc cttacagaag cccgatacct gctagatcac 850

 ttcctgtcaa tgggcatcaa taagggtctt caggctgccc agaaagaggc 900

 tcaaattaaa gtactggaag gtcgactcaa acaaacagaa ataaccagtg 950

 ctacccaaaa ccagctctta ttccatatgt tgaaagagaa ggcagaatta 1000

 aatcctgagc tagatgcttt actaggccat gctttacaag atctagatag 1050

 cgtaccatta gaaaatgtag aggatagtac tgatgaggat gctcctttaa 1100

 acagcccagg atcagaagga agcacgctgt cttcagatct catgaagctt 1150

 tgtggtgaag tgaaacctaa gaacaaggcc cgaaggagaa ccaccactca 1200

 gatggaattg ctgtatgcag atagcagtga actagcttca gacactagta 1250

 caggagatgc ctccttgcct ggccctctca cacctgttgc agaagggcaa 1300

 gagattggaa tgaatacaga gacaagtggt acttctgcta gggaaaaaga 1350

 gctctctccc ccacctggct taccttctaa gataggcagc atttccaggc 1400

 agtcatctct atcagaaaaa aaaattccag agccttctcc tgtaacaagg 1450

 agaaaggcat atgagaaagc agaaaaatca aaggccaagg aacaaaagca 1500

 ctcagattct ggaacttcag aggctagtct ttcacctcct tcttccccac 1550

 caagccggcc ccgtaatgaa ctgaatgttt ttaatcgtct tactgtttct 1600

 cagggaaaca catcagttca gcaggataag tctgatgaaa gtgactcctc 1650

 tctctcggag gtacacagat cctccagaag gggcataatc aacccatttc 1700

 ctgcttcaaa aggaatcaga gcttttccac ttcagtgtat tcacatagct 1750

 gaagggcata caaaagctgt gctctgtgtg gattctactg atgatctcct 1800

 cttcactgga tcaaaagatc gtacttgtaa agtatggaat ctggtgactg 1850

 ggcaggaaat aatgtcactg gggggtcatc ccaacaatgt cgtgtctgta 1900

 aaatactgta attataccag tttggtcttc actgtatcaa catcttatat 1950

 taaggtgtgg gatatcagag attcagcaaa gtgcattcga acactaacgt 2000

 cttcaggtca agttactctt ggagatgctt gttctgcaag taccagtcga 2050

 acagtagcta ttccttctgg agagaaccag atcaatcaaa ttgccctaaa 2100

 cccaactggc accttcctct atgctgcttc tggaaatgct gtcaggatgt 2150

 gggatcttaa aaggtttcag tctacaggaa agttaacagg acacctaggc 2200

 cctgttatgt gccttactgt ggatcagatt tccagtggac aagatctaat 2250

 catcactggc tccaaggatc attacatcaa aatgtttgat gttacagaag 2300

 gagctcttgg gactgtgagt cccacccaca attttgaacc ccctcattat 2350

 gatggcatag aagcactaac cattcaaggg gataacctat ttagtgggtc 2400

 tagagataat ggaatcaaga aatgggactt aactcaaaaa gaccttcttc 2450

 agcaagttcc aaatgcacat aaggattggg tctgtgcctt gggagtggtg 2500

 ccagaccacc cagttttgct cagtggctgc agagggggca ttttgaaagt 2550

 ctggaacatg gatactttta tgccagtggg agagatgaag ggtcatgata 2600

 gtcctatcaa tgccatatgt gttaattcca cccacatttt tactgcagct 2650

 gatgatcgaa ctgtgagaat ttggaaggct cgcaatttgc aagatggtca 2700

 gatctctgac acaggagatc tgggggaaga tattgccagt aattaaacat 2750

 gaatgaagat aggttgtaaa ctgaatgctg tgataatact ctgtattctt 2800

 tatggaaaat gttgtcctgt acttactagg caaaacgtat gaatcggatt 2850

 aactggaaaa tatatctgaa ttcaactgct gactataaat ggtattctaa 2900

 taaaattgtg tactatcctg tgtgcttagt tttaagatca accaatagat 2950

 atatatccta caattgatat attgctttat tcacactttt attgtggctg 3000

 aatttttgtg cctatctata aaacacactt tcaaattatt tgaattacca 3050

 agacgtctgc ttttgtgaca gtcagaaaac acacctggaa tacgatgcag 3100

 cccaccatta actcattcat gtagtttatt caagtgattt atgtatttaa 3150

 actaaatatt gaaaatgtta gtcaaattgt ggtttgcttg tcaggtattt 3200

 atatcagtct gtagtggatt cccaaatttc aaagctcttt taatgtaatg 3250

 gacaaaaata agatatgaga atattattga tgaattttca taaggtggaa 3300

 ttgatcttaa tctactaaca gagaagggta gacagtttgt gttaaatgtt 3350

 ggcatttact tgtattgacc aaagttttgc agctctacta tattctgtgc 3400

 tcaggactaa aatgctgtta attttttttt ttttttccag tgctgtgcat 3450

 atattctgtg atgggaaaca ttgttgatgt cctaacagaa atatattttg 3500

 atctattttc ctatggagtt gtttctatta tgaccattta attttgtttt 3550

 tatttaatag tagtatttcc ttccctttta tctaattttt tatatgctgc 3600

 taaatatatt ttaaatatac tatgtttgcg aaccttggta gctatgatga 3650

 gagctattat catctgtggt gggaaaagct atgtaaatag gtagattgta 3700

 tagagagact atcttgtgtt gtgcctgtat gaatttttaa aagttgttga 3750

 ctggattttg caaaaggatg tataatattt ctgtctgctc agaatattaa 3800

 tttgtaaatt ctgcaagttt aatttttatg tagatggtat aacatttgaa 3850

 aatattgtct tatgtgattt tttcccctga aaatatttgc ttgtaaatga 3900

 aaacttagct agggcttaaa taaacatgtt gctatgaaat t 3941

<210> 4305
<211> 914
<212> PRT
<213> Homo sapien

<400> 4305
 Gln Asp Val Met Glu Met Lys Lys Thr Lys Val Arg Leu Met Lys
   1               5                  10                  15

 Gln Met Lys Glu Glu Gln Glu Lys Ala Arg Leu Thr Glu Ser Arg
                  20                  25                  30

 Arg Asn Arg Glu Ile Ala Gln Leu Lys Lys Asp Gln Arg Lys Arg
                  35                  40                  45

 Asp His Gln Leu Arg Leu Leu Glu Ala Gln Lys Arg Asn Gln Glu
                  50                  55                  60

 Val Val Leu Arg Arg Lys Thr Glu Glu Val Thr Ala Leu Arg Arg
                  65                  70                  75

 Gln Val Arg Pro Met Ser Asp Lys Val Ala Gly Lys Val Thr Arg
                  80                  85                  90

 Lys Leu Ser Ser Ser Asp Ala Pro Ala Gln Asp Thr Gly Ser Ser
                  95                 100                 105

 Ala Ala Ala Val Glu Thr Asp Ala Ser Arg Thr Gly Ala Gln Gln
                 110                 115                 120

 Lys Met Arg Ile Pro Val Ala Arg Val Gln Ala Leu Pro Thr Pro
                 125                 130                 135

 Ala Thr Asn Gly Asn Arg Lys Lys Tyr Gln Arg Lys Gly Leu Thr
                 140                 145                 150

 Gly Arg Val Phe Ile Ser Lys Thr Ala Arg Met Lys Trp Gln Leu
                 155                 160                 165

 Leu Glu Arg Arg Val Thr Asp Ile Ile Met Gln Lys Met Thr Ile
                 170                 175                 180

 Ser Asn Met Glu Ala Asp Met Asn Arg Leu Leu Lys Gln Arg Glu
                 185                 190                 195

 Glu Leu Thr Lys Arg Arg Glu Lys Leu Ser Lys Arg Arg Glu Lys
                 200                 205                 210

 Ile Val Lys Glu Asn Gly Glu Gly Asp Lys Asn Val Ala Asn Ile
                 215                 220                 225

 Asn Glu Glu Met Glu Ser Leu Thr Ala Asn Ile Asp Tyr Ile Asn
                 230                 235                 240

 Asp Ser Ile Ser Asp Cys Gln Ala Asn Ile Met Gln Met Glu Glu
                 245                 250                 255

 Ala Lys Glu Glu Gly Glu Thr Leu Asp Val Thr Ala Val Ile Asn
                 260                 265                 270

 Ala Cys Thr Leu Thr Glu Ala Arg Tyr Leu Leu Asp His Phe Leu
                 275                 280                 285

 Ser Met Gly Ile Asn Lys Gly Leu Gln Ala Ala Gln Lys Glu Ala
                 290                 295                 300

 Gln Ile Lys Val Leu Glu Gly Arg Leu Lys Gln Thr Glu Ile Thr
                 305                 310                 315

 Ser Ala Thr Gln Asn Gln Leu Leu Phe His Met Leu Lys Glu Lys
                 320                 325                 330

 Ala Glu Leu Asn Pro Glu Leu Asp Ala Leu Leu Gly His Ala Leu
                 335                 340                 345

 Gln Asp Leu Asp Ser Val Pro Leu Glu Asn Val Glu Asp Ser Thr
                 350                 355                 360

 Asp Glu Asp Ala Pro Leu Asn Ser Pro Gly Ser Glu Gly Ser Thr
                 365                 370                 375

 Leu Ser Ser Asp Leu Met Lys Leu Cys Gly Glu Val Lys Pro Lys
                 380                 385                 390

 Asn Lys Ala Arg Arg Arg Thr Thr Thr Gln Met Glu Leu Leu Tyr
                 395                 400                 405

 Ala Asp Ser Ser Glu Leu Ala Ser Asp Thr Ser Thr Gly Asp Ala
                 410                 415                 420

 Ser Leu Pro Gly Pro Leu Thr Pro Val Ala Glu Gly Gln Glu Ile
                 425                 430                 435

 Gly Met Asn Thr Glu Thr Ser Gly Thr Ser Ala Arg Glu Lys Glu
                 440                 445                 450

 Leu Ser Pro Pro Pro Gly Leu Pro Ser Lys Ile Gly Ser Ile Ser
                 455                 460                 465

 Arg Gln Ser Ser Leu Ser Glu Lys Lys Ile Pro Glu Pro Ser Pro
                 470                 475                 480

 Val Thr Arg Arg Lys Ala Tyr Glu Lys Ala Glu Lys Ser Lys Ala
                 485                 490                 495

 Lys Glu Gln Lys His Ser Asp Ser Gly Thr Ser Glu Ala Ser Leu
                 500                 505                 510

 Ser Pro Pro Ser Ser Pro Pro Ser Arg Pro Arg Asn Glu Leu Asn
                 515                 520                 525

 Val Phe Asn Arg Leu Thr Val Ser Gln Gly Asn Thr Ser Val Gln
                 530                 535                 540

 Gln Asp Lys Ser Asp Glu Ser Asp Ser Ser Leu Ser Glu Val His
                 545                 550                 555

 Arg Ser Ser Arg Arg Gly Ile Ile Asn Pro Phe Pro Ala Ser Lys
                 560                 565                 570

 Gly Ile Arg Ala Phe Pro Leu Gln Cys Ile His Ile Ala Glu Gly
                 575                 580                 585

 His Thr Lys Ala Val Leu Cys Val Asp Ser Thr Asp Asp Leu Leu
                 590                 595                 600

 Phe Thr Gly Ser Lys Asp Arg Thr Cys Lys Val Trp Asn Leu Val
                 605                 610                 615

 Thr Gly Gln Glu Ile Met Ser Leu Gly Gly His Pro Asn Asn Val
                 620                 625                 630

 Val Ser Val Lys Tyr Cys Asn Tyr Thr Ser Leu Val Phe Thr Val
                 635                 640                 645

 Ser Thr Ser Tyr Ile Lys Val Trp Asp Ile Arg Asp Ser Ala Lys
                 650                 655                 660

 Cys Ile Arg Thr Leu Thr Ser Ser Gly Gln Val Thr Leu Gly Asp
                 665                 670                 675

 Ala Cys Ser Ala Ser Thr Ser Arg Thr Val Ala Ile Pro Ser Gly
                 680                 685                 690

 Glu Asn Gln Ile Asn Gln Ile Ala Leu Asn Pro Thr Gly Thr Phe
                 695                 700                 705

 Leu Tyr Ala Ala Ser Gly Asn Ala Val Arg Met Trp Asp Leu Lys
                 710                 715                 720

 Arg Phe Gln Ser Thr Gly Lys Leu Thr Gly His Leu Gly Pro Val
                 725                 730                 735

 Met Cys Leu Thr Val Asp Gln Ile Ser Ser Gly Gln Asp Leu Ile
                 740                 745                 750

 Ile Thr Gly Ser Lys Asp His Tyr Ile Lys Met Phe Asp Val Thr
                 755                 760                 765

 Glu Gly Ala Leu Gly Thr Val Ser Pro Thr His Asn Phe Glu Pro
                 770                 775                 780

 Pro His Tyr Asp Gly Ile Glu Ala Leu Thr Ile Gln Gly Asp Asn
                 785                 790                 795

 Leu Phe Ser Gly Ser Arg Asp Asn Gly Ile Lys Lys Trp Asp Leu
                 800                 805                 810

 Thr Gln Lys Asp Leu Leu Gln Gln Val Pro Asn Ala His Lys Asp
                 815                 820                 825

 Trp Val Cys Ala Leu Gly Val Val Pro Asp His Pro Val Leu Leu
                 830                 835                 840

 Ser Gly Cys Arg Gly Gly Ile Leu Lys Val Trp Asn Met Asp Thr
                 845                 850                 855

 Phe Met Pro Val Gly Glu Met Lys Gly His Asp Ser Pro Ile Asn
                 860                 865                 870

 Ala Ile Cys Val Asn Ser Thr His Ile Phe Thr Ala Ala Asp Asp
                 875                 880                 885

 Arg Thr Val Arg Ile Trp Lys Ala Arg Asn Leu Gln Asp Gly Gln
                 890                 895                 900

 Ile Ser Asp Thr Gly Asp Leu Gly Glu Asp Ile Ala Ser Asn
                 905                 910

<210> 4306
<211> 3676
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1907-2072
<223> Unknown base

<400> 4306
 tgggaatata aatgtcaagt tacatctgac ttgagctcag cagaataaac 50

 aaaactgtga atcattaaga ggatgcttgt gaagacatgc ttacttttat 100

 ctttgcttgg gtgagtttga aaggcaaagg aagataacca aaccagttcc 150

 ctgttggttg ggggccattc ttaacgtgta ctgaactgaa caagcagcaa 200

 aataggtgga aggtgatttg aatcactcca aagtcaggct tggagtccca 250

 agtctgacct ggaaaatgga ctctagctct gcctcttatc ccacacatgt 300

 gtgtgtctgt gtgaacatgt gtgtgtgttg gtggtttgtt ttgttttgtt 350

 ttcctcttat gtacttggga agcagttgct gagggtcttg cggagctctg 400

 tttcctccag tgtagcatag cagcaggtgc aggggtccaa agctatggtg 450

 gcaaaatgaa gaatgaaagg aataaattgc acactatcat ttcaacatgt 500

 aacccagtga atcaaactga aggtaggatg tctatatacc cttcatttca 550

 ggggccccta gagaatatac cttagctttc cctcttccgg catcctggaa 600

 agtggatacc tgtggccttc ctttcacttt gaaagcttac accctcattt 650

 tgactacaac taatactaaa agcttggcat cttgcttgag attagtgttt 700

 gctatgccaa acaccttctc ctctttctat tgaaagcaaa acataggaaa 750

 ataatttgaa atacttttaa ggcatcttaa aaacatgact ttttcatctt 800

 atggaaaagc agaccaattt tgcttttttt tcccaacttg ttctccagac 850

 tgtgccaata aaatgtgttc atagcaggaa aatttggaaa atacagaaaa 900

 gcactatgaa gaaaacaaaa tgtacccaaa atcccatcac tcagataaca 950

 tcactgttaa tgttttgata tgtatttcca gtcttttcta ttgtgttaat 1000

 ttttcatttt gtttttgaat aaataacttt caggaaagaa attgagcctt 1050

 ttctgccacc tctgaagcct gattactgtg tgaagcaggc catgaaggcc 1100

 atcctcactg accagcccat gatctgcact ccccgcctca tgtacatcgt 1150

 gaccttcatg aagagcatcc taccatttga agcagttgtg tgcatgtatc 1200

 ggttcctagg agcggacaag tgtatgtacc cctttattgc tcaaagaaag 1250

 caagccacaa acaataatga agcaaaaaat ggaatctaag aatctttttg 1300

 tatggaatat tacttctatc agaagatgat caagatgttt cagtccagtg 1350

 cacatcagca ttgctgacat tttatggatt ctaaacttgt gttgtttctt 1400

 ttttaaatca actttttaaa aaaataaagt gtaaattaac cgactagagt 1450

 acttggaaaa tgtgatcagt acaagtgaac ttaggttgtt gccaacaggg 1500

 tccttttagg cagaacccag aaaccagtca aatctgtaga gaagcagtgt 1550

 gacatcttca ggttaccatt attttttaat gagcaggaag tctagaaatg 1600

 ataactagac tgtatgtttc atgtgtgtga tttttcagaa ttcccagagt 1650

 ttactcattc ttgttattaa actctagcca gttgacatct tcgcaatttc 1700

 aaggactgat agtgctgtat tttctcacgt tttctaagtt tccgttttgc 1750

 aaggcctagg tgactttttc atggtgtttg tatgtttagc tcttttgaaa 1800

 aggaattttg aaatctccat caactgaagt aaatgatgtc tgagtgttac 1850

 agtaaaggtg accaagtctc tttcttaaag tcacaatgac taaagtatta 1900

 gttgaannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2050

 nnnnnnnnnn nnnnnnnnnn nnttgaattt ttaattttat ctctgatata 2100

 cttcattagg tctccagaca cttaatgaag tatatcagag ataaaattat 2150

 cctaaaagat catacatttt ctacctatga attttgctgc atacagaaag 2200

 tgccctttcc tcaggaagtt gctgtgtttc atttctttgg atggactctt 2250

 atctagaata catagcagct ctgcaaagaa acagttttta aaaatgggaa 2300

 cttctacatt gaaaagtccc catttttgtg ccaactatga ttagtgagag 2350

 gaagaaatct tattctatgg catatgtatg gaagggtgta aagattcttt 2400

 tgaaaggttt attcacattg tagaacagca aatgacattt ttacagtatt 2450

 tttttgtaaa gcaaactatt ttgtgccttg aatttggtat atgtgtatta 2500

 gtgaaacatt gtaaaggtga acttctacct ctgtatctaa atgtatacca 2550

 tccacttgta aatgactata aactattatg tgattgcttt tttttttaga 2600

 atgtcttgtt taaatagtgg ccaatgttta aggctgttaa aataagccaa 2650

 cttttactaa ttggggagtt ttataaatga ctgattaaat ttaaagaatt 2700

 aacttacatg caattgtgtg attattagtt atcagcagtg ttgtaaggaa 2750

 aattattgtg ttttttttta tgatcattat cccactttag gtaaagaaaa 2800

 atattggaat ggaatagtgt tgggaaacag acattaacaa cctagggtgc 2850

 ctgcactcaa atagccgatg ttactgtccc tagattagag acttgattaa 2900

 gggcttgttt gtaccaaaag tggggaaaca atgccatgac ctgtgtttta 2950

 gtttggctgc accacagatc aaatctgcac tgtgtctaca tataggaaag 3000

 gtcctggtgt gtgctaatgt tcccaatgca ggacttgagg aagagctctg 3050

 ttatatgttt ccatttctct ttatcaaaga taaccaaacc ttatggccct 3100

 tataacaatg gaggcactgg ctgcctctta attttcaatc atggacctaa 3150

 agaagtactc tgaagggtct caacaatgcc aggtggggac agatatactc 3200

 agagattatc caggtctgcc tcccagcgag cctggagtac accagaccct 3250

 cctagagaaa tctgttataa tttaacaacc cacttatcca ccttaaaact 3300

 gaggaaagtc gtctttacat ctaattttat tcttgtgtgt tataacttaa 3350

 acctatttct atttttgttt gttattgccc ttataagggt gtccatctcc 3400

 aagttcaata aactaattca tttaactttt ttgtagaagt ctttcattcc 3450

 catgtcccag cccagttcaa tcacttctgt ggctcttcct tgaatgttgt 3500

 ccatattctc cctcccatct ttagctgtgg agtttggaaa gggatacagt 3550

 taatgcaggt ttagaactat ggaattccta caagttgcat ttcttcatcc 3600

 caatgtcacg ttcttattaa tgctacattg ctgattgtgt gcattattgt 3650

 ttctaaacat gaaatctctt ctagac 3676

<210> 4307
<211> 5
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1907-2072
<223> Unknown amino acid

<400> 4307
 Met Lys Ser Leu Leu
   1               5

<210> 4308
<211> 3774
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3720, 3724, 3744, 3769
<223> Unknown base

<400> 4308
 ctgatataac tgcaaattaa cagtaaatct ctgcctacca tcctgaaaga 50

 atattcacga tatgtggtgt ttttcttatt ctagcccagt tttttctgtg 100

 aattcagatg gatacggata agttgtgaga ccttggggaa tcattcttct 150

 ctgggcctgc ttcctcctct gttgtctagt ctaacatccc cttccaccct 200

 aggtttctat ggctattctt tttctactta ttagaaactt gcgaatcatg 250

 ctggttacag caatttatta taagctaagt aatgtaaaat atgtctaaag 300

 ttgaagtact ttaggcttat ttccttgtct ttggtgaaat acatctcagg 350

 atgcttaatt tttaaatttt atctttaatt ctaggctata ccccagcttt 400

 ggcctgtgct cccaataagg atgtggctga ttgcctggct ctcattttgg 450

 ccaccatgat gcctgtctca tcaagtagtc ctttatcatc cttaacattc 500

 aatgccatta accgttatac caacacctca aaaacagtca gctttgaagc 550

 tttgcccatc atgaggaatg aacctagctc ctattgcagt ttcaataaca 600

 ttggagggga acaggagtac ttatacactg acgtggatga gctcaacgac 650

 tccgattctg agacctactg agaggctgag gaggagggag ttctcacagt 700

 aaagcttcaa actgtgcttt ttcaggaaaa aggcactttg atattcacgt 750

 agaaattcaa cctaagagga aagatcccac agtgagccaa tgttaagaga 800

 tctgatggca ttaggaggaa gagttttaaa ggcaagtttt acaaaaggaa 850

 cttctagaat cttgaaatag acctgactga ggaaaacaca ttgatgtcag 900

 aattctttgt ggaattgttt aatttggttt tgcagtgcca ggaacaattg 950

 gggacactgt gcactctaac ctgcttacac aagcaacact attgtaacag 1000

 aagaaataaa gacactagat ttaaatttta tcaataaaat tacaactaaa 1050

 tttaaaggca ataaaagttt ggtacagtag gcattatgtg cacagcaaat 1100

 tgcaaaagga ccaaataact gaaaggtttt tttaataaaa tgccattttg 1150

 tggaaactgg agtagattaa atgaaacatt acctaaacca aactgcaata 1200

 tttctggaaa tgaagctgag atttggtttt aaatgttgag tttttttggg 1250

 ttttgttttt tttttaagaa aacatctgaa agccttccaa tgctgtatta 1300

 aaccatgaga gaaagcagat gtatttttac atttttttct tttacagaac 1350

 tatttcaaat ttccaatttt tatactatta gaattaaaaa ccagctgact 1400

 gggtgcaata cgggtgaaaa tacttgtgac atagacattg agatggattg 1450

 gggtcaggct gttgccctgt tttgaatggt ttgggtttaa aatagtacta 1500

 tttttgtttg aaaatgtaaa gaatttccta gaaaaaaatt catgaaatca 1550

 aaaagtagac tatttcaccc tattgcagct aagtggtcct ggggcatgga 1600

 gtcttcaacc tctctatgaa tggcacacct tagtcactta tgttactttt 1650

 gtgtccccac catgggttgg gggatttttt gtttattctg atctatgagt 1700

 tttgaaaaag tgaataatca aaaggaaaat aattccttgt tgttcataaa 1750

 ttaagcatca ctaaagtctc ttgaaaggca tttctgtatt gggcaagatt 1800

 taaaatacta aagccttagg tcctattcat atttaaagta gcatgtttgt 1850

 aacctgttac tatttggaga gagaagcagt tgcctgccaa attgaagact 1900

 acctttcaaa tagcaaaaga gagagagaag gctgatattt cggcttttaa 1950

 ataaagattt gtgtggttct gcttttactg taactgtcac tttcccagtg 2000

 aaaatgattt catatacatt gagggtctta caggtatggg taaagttcta 2050

 taaattgcaa caaaatgata cccaatttca ttttatcctt tttgtattgt 2100

 gaaactggaa actttatgac attgtaaatt atcagctggt ttttctgaat 2150

 ataaagtgtg aaaacacaga acagtatttt gatctatttg ataattttgt 2200

 gggttttttg aagaattaat gagcatgtac atagaaatag tgactgcttg 2250

 aatactgtat ttacttgcac tctttcagta catcaagatt cctgtatatt 2300

 ttagagtata ataaaacaca gatgtgagtt gtatttaatg aataatgtat 2350

 ttgtatctgt gcatattatc tacaaatcta taaagtttct agggcattga 2400

 ctactagatt ttaagcattt tttctaaaat atttacagaa attataaatc 2450

 taatccccca tcttttcttt ataatataaa gaagtcataa tgaacccttc 2500

 ctaattatta gtagtaggaa ggtgaatatg cattttaatg acagtggact 2550

 acattttcta ttgtaccttt tgaaaaaaaa aaaaatcaag cagattctaa 2600

 aagtatacat atgtgtgctt tctctttcct tttaggaatt ctcttctgaa 2650

 ttccctgagg gaattttcta gaatctcaga attgaaagag acctgaggtt 2700

 catccagtct ctaacctctt aacaaatgca ggagtccctt ctacaagggt 2750

 gatctttcca ccttgaacac ttccaagtga ctctacctca ccaagcagtc 2800

 cattcagttg ttgagcagct ctaactgtta gaaaggtctt ccttagatgg 2850

 agttgaagcc tccctcccgg taacttctgt ctttgggcct gggtctgtcc 2900

 tccaagagaa ccctgagaat gttggaagga tgaatctcgc acattctgcc 2950

 atgtcttctc ttttacaggc tgtttgactt ctctgctgaa gtgatttcca 3000

 gaaggactca tttgacacac tattagattt accacatcta atgaaatcca 3050

 aggtgtagct ataaagtgac aagctgtttt taatttatca catacaccag 3100

 aacttctatc ctgcatcact tatatgtaaa tgatgctgtt accaaaaaca 3150

 ttaaggtagt tcttgcgaat gccaccccac taagaaaact atttcattac 3200

 ttttgtaatc catctgtgag agtctgcccc ccagcttaac cacttccttt 3250

 ggtctgcacc caatgaaggg aaaccccaaa gtactgtctc aaatggtatt 3300

 tgaactacgc cagtattgtt ggaataagta cattaattac ttgaatgaat 3350

 gaacacagca ccgtagaaat ttcctttatg gttacacctt gtatgtctaa 3400

 agcattcagg ccctgttctg tagtgtttct tatcctcaca cagagtagaa 3450

 aagcctgttt gctttattta acttatacat aaaagatgac atctgaaata 3500

 tctgatgtgt attataatac cagcttctgc tctagaacta ctttgggtga 3550

 aatggtggta atagcaaatg acctccttta acaagacact catctcaaac 3600

 aatgccattt agttcaggag atctctaagt gtagctgtaa attttggggt 3650

 taatttggct tatattggac cttttaaaag aaataaagtt ttttaatgca 3700

 ataaatcaag tgtctgtctn tttnacatgc aaacttcttt tccnataaac 3750

 tgtctagcat tgaattgana agtt 3774

<210> 4309
<211> 5
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3720, 3724, 3744, 3769
<223> Unknown amino acid

<400> 4309
 Asp Ile Thr Ala Asn
   1               5

<210> 4310
<211> 2165
<212> DNA
<213> Homo sapien

<400> 4310
 ctattttgtt tgtagtattg tggaacagtc ttgttatgga gtgccagctt 50

 agaggttgtt gcaaacttgt ctagaagtga gagcatggtt ttttttagcc 100

 ctttgagagt ctacatctaa tgaacattct tgctcaccca taaataacgt 150

 caagcctcaa tgtcaccgtc acgttgggat actctttctc atctggcatc 200

 ctagacagga caaggttggt tacctttcct tccatgaacc atgaacctgt 250

 gacggcatca ttcatcctga cttcaccaag ctccgcctgt gggtgaggcc 300

 agagctccca ctggcaattt ttagaagagc cagaggctcc ctgcttcctc 350

 tagaaataac agttcagggt gaagcatgga gggtttcagt tcccagacaa 400

 cggaaccatt tagagacaac acagttggac atttccactt tttccttgat 450

 tcctggaagt ccagtgggtt ctgcagctga aaaagccctg ggtcccagca 500

 gcagagagac aggacagagg ggatgcttgg gcggggaggg acggtaacct 550

 gcagaacaga ttccattttt atagaacgag tacacgtttg ctaaaacagt 600

 cctgctttcc cagactggat tcccaccaca gggacagtcg gaactcagga 650

 ctagctccag cgacatcttt cctccgaatt caagccttct atcacaatgt 700

 caaaacagct atttataaag ccattttcat tgtacttgat aacagcacga 750

 gtcccaaaac ttttagaaat aaaataggac attggcttga ttgaaaagag 800

 ggacttttta aaaattgttc tttcgtcaga agccttttgg atgacttaca 850

 atagctctga tgaagatacc accccagcgt cagtccaata ggtcagtgag 900

 tttcaacagg catccatccc tcccatgaag ggattctggt gatgggaagt 950

 ttctgtaatg acaggaaagc attgaccctc attgattgtc aactttggta 1000

 ttagccatga aagacaggat gctcattggg tgttctgtag agtgaggaat 1050

 gctgcctatt ccctcccaga acgtctgacc caggggtgtg tgttgaggag 1100

 ccctggggga aatggaccaa gttttcccac agagcagtat taggctgaag 1150

 agcaggtgac tggtaggccc cagctcccat cattccctcc caaagccatt 1200

 ttgttcagtt gctcatccac gctggattcc agagagtttt ccaatttggg 1250

 aagccatgag aaaggttttt aaatcttggg aagatggaga gagggacata 1300

 ggatagttga ctccaacatg acaggaagag gctggagatt gggaattggc 1350

 catcaaccaa gcctgtagta gtaaagccat ggtcccgcat tggaattact 1400

 tggggaactt atacagttct gatacccagg ctctcctaga ccagttcaac 1450

 caattctagg tgggggactc aggcatcagt gtgtttcgta gctccccggg 1500

 tgttttccct gtgcagccga gcttgggaaa ctgccatgct ttttggatgt 1550

 caaggcgctg ttggaggctg ggtgtgacag cacagagcca ggttgtcttg 1600

 tggaaaccac agccacgggt ttgccactgg ctcagcatgg cctcactgcc 1650

 agtcccagcc tggctgaggg acaagatggt ttctcttggg agttcctgag 1700

 tggagcaccc ttccaggctt tttgaaagcc agctgatctg tggagccttg 1750

 ttaagggact caatacggtg tttggatatt gatgtttttc cttgagactg 1800

 tcttgtccat caataaagat ggaggatgtc tcctctttga accccgcttc 1850

 cccaccagta ctctctctcc cttagagttt atgagttatt caaggaggag 1900

 acttcttaaa gacagcaacg caattcttgt aacttgtgta aatagcccca 1950

 tctttcagag tgataccatt tctacatttg ataatgcctg tattcctgta 2000

 ggatgtatat agtttagggg attttttttt tgtttggttt tgttttttag 2050

 aagtcaatat gtctggtttt atttattgct tgaaaaagat catttgaaaa 2100

 aaataaatac attttcaatt ccagaaagga tctatgtcgg gtgcggagaa 2150

 agaggtaatg aaatg 2165

<210> 4311
<211> 9
<212> PRT
<213> Homo sapien

<400> 4311
 Met Ser Gly Ala Glu Lys Glu Val Met
   1               5

<210> 4312
<211> 4969
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 962-1140, 2856-2915
<223> Unknown base

<400> 4312
 gatgaagtat caatcatcag ttcccagcca gtctgcttgg acacactggg 50

 gtgccacaag tgggttgcag gttggttgca gacgggcaga gatgggttct 100

 ggttggcttt caaaatggac cacgggctgg ggcctagcgc tggggcaagg 150

 ttccagctgg ctgcctctag cctggaggag cttcatctag ttacccaatg 200

 tgctgaacca acagcatgaa atagcatcat ttcctgtgct gtgttacaaa 250

 gtgcaaacgt ttggaaacac tgatacagta caattatttc catcactcca 300

 tgttgttata atttttagtt acttttcttg attgaaaagt caatcacatt 350

 gccaaaaatg atttttatgt cagttaaagg ccagttgaaa tttttttatt 400

 aggatgtttt aaatttactt ttcactttct tgaatttttt tcttctcaaa 450

 tttccttggc ccagtgccca tgagcaaatt tcattcaaaa acaggaataa 500

 ccttttgtca taaaattttg gcaccagctt ggtatactaa attactgcaa 550

 agataactga gtaccagaag taaaaatctc tgcaggtggg cttaggagta 600

 ctcttgggtc cctggttcct cagttgccaa ctctggtttc atgaagaaag 650

 accatgctct gaaaatctag ggaggagaaa gttattgcag cacctggtgt 700

 gatttgttac aacttcttta aagacagcct gcctggctag ctttttcctg 750

 ttttcatgca gtttgccctc ccagcattgg tccacctgtt gttcccaaga 800

 aactcattct gttcccaaga ctccttttag ccaaatcttt cctatcattc 850

 caggactttt ttgtgcttct ctccccatga atctacccgt gcctagggtg 900

 tgtgccaggc acgtggcagg tggccagtca gcatctggat gtgagaccaa 950

 ttattccagc cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1050

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1100

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn tccagccccc 1150

 tttctctctc ttaactccct ctccctgctg tcgttgccat actcttgcat 1200

 acacaatcgg ttgtctagtt tttgattgtt tgtgtgtatg gtgtgtgctg 1250

 tctctctgac cagatttcag gttcctgagg cgagcctgca gctcatactg 1300

 ctcatctgtc ctctcctatg gtgggtgctc agggcctctc actgttagtt 1350

 actccctcct ttctgcccag ttctgcactc aactagtaga agcagccatc 1400

 ctttccccaa gcaggaaatt gtagtggtcg cccttaagag cagtgtgagg 1450

 gcagaagatt aagggagggg aagagtccct ggaactggaa gaaggtaaat 1500

 actttgcctt gagagggcgc cgaatcattt taccaaaata gtaaatggaa 1550

 aaagtgtcaa aggttgggac tagttttaaa aacacatata gccagtagac 1600

 acatgggggc tgtttaaata aaaacatttt tttacccggt tctgccataa 1650

 cacacactag tgacattcca agtactcagt ggccatgtgg agctagtggc 1700

 caccacactt gacaccacgg atgcagaact tttccatcac tgcagaaagc 1750

 tctgttgaac agtactgtgt ccagagtgct aattatgaac agcttagaaa 1800

 ccacaattaa tacattctca tgaggttaaa agcagacatg ggaatagaac 1850

 ataatgcaaa tgatgatgaa tattttgggt gagaagagaa agctgaggac 1900

 ccatttctag gattctaaga tgtaagattt cttaagttct ttatcttagt 1950

 ctcatgcatt ctccacatca cgcgctgtac catactgtgt agtcagaaca 2000

 gacagtgtga ttgaaaagct ttggaaaaag ttaacacaaa ggattattta 2050

 gcacataggc tgtagatacg tatgtgtgta tttgttcaac aattggagat 2100

 ggttgaatac ccttgaacaa agtgtgtatc ttctcaaatc agtggttgca 2150

 ctagtcaata attagaaggt gttgttattt ttaaaactat aagcaaaatt 2200

 atgaaggcct ttaaaaaatc tatcataata atgaaaaaga ggttgtctcc 2250

 caacagtgct gtccctcaaa gaaaagactg gttatgtgga aacagcacgt 2300

 ttggagagat tattctagtg aataacagtg tatatttgtg gtaggcaaat 2350

 ttctaagaat gacccctact gacaccccca ccaatgacct tgtataatat 2400

 cctcccactt tgagcatggg tggaacctgt ttgatccatg attatatcat 2450

 gttatgtagc aaaaggaaga ctgtctgggg gtggctaatc aaatcttgtg 2500

 actcctttaa aagcagagag ttttctcggg ctggtggcag aagtcaagag 2550

 acaaagcaga aggacctcag gcaccattgc tgttttaagg tagagggggc 2600

 tgcatgagaa ggaatgcaca tggctttgag gagctgagag aggccttggc 2650

 taacagcaaa ggagctggga actgcagtcc tacagccacg ggaactgaat 2700

 tcagcccata agctcattca taggcttgga aaggcattca tctccagtct 2750

 ccagataaga cccagcctgg ccaacacttt gaatccagcc ttgtgagacc 2800

 ctaagccgag aactcactta agcctgcttg gacttctgac ctacacaact 2850

 atgagnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2900

 nnnnnnnnnn nnnnngaaat gaatacagta ttttaaaaga ggtaaagagg 2950

 aaatcttcat acttgattcc ctgtagtatg ctggatattt cttggtaaat 3000

 gcatgaataa agtctttagt agcaagtcat gtacctggac ctcgttgggg 3050

 atgttctcgc cagagatctc aattagtctt cattggacgt ttgttggcaa 3100

 agttgcagca tcttactgag tagcgtttgg taaaggaact gctagaatga 3150

 gactatagga ataggactga aacagtgtgt aagggatctt ttttatttct 3200

 agaagaggtg ttactttata ctgatttaga ctgctctgag cctgtcagaa 3250

 gtaaattcaa gaatgattaa cagtggtatt ttagatacat taagagcaaa 3300

 aataaccttt gccttgtaga gatcagataa tctgtgtatc gagggattta 3350

 atttttttta accaaaactt agtttctctt tttatcatct agcacagatc 3400

 aaatcctgta tgggccagcc aaatgtttgt agtttgagaa tgttttgcaa 3450

 atacctctct gcttccaagc cattaatagc taatgaagtt ttattttggt 3500

 ttgtccatta atttttctgc ttatttttac tgtattgcca tgtccttgat 3550

 acgagacaag tagaactaaa agagagaaaa tgagaggtta agactgtcag 3600

 aagatgagaa atgtgagtca taaccatacc ttagtgtttt aagggaactt 3650

 tatccagtcc aatcccttta tagaaaagga acttttccaa gttatgttgc 3700

 agtatttata gtgtgtaaaa ttttgtttga ctttggtagt tgtgcatttt 3750

 aaattatgaa tcttatatgc tacgataact agtatgctta ctttctttaa 3800

 tgcatgtgat catacaatgc taaaaaggta ttttttaaag acccaaccaa 3850

 actgaggatt ttgttataca tatctgtatc aacacctata tataaactct 3900

 tcttcttacc tgaaacactc cttcacccgg tttgggcact aactagatca 3950

 ttttcaaagg aacaaacagg aaggagcaag ctggcactcc agggtgcatc 4000

 tgagctgaga atttagaaga cctcattcaa gaaagtaaac tgagcattga 4050

 tgggaaagca ctttgcgcga agtaacattc ccactgttaa tgttgcagtc 4100

 aaaattgtgg aaaaaaaaaa gtggtgctaa aattgttctg aaatgaagat 4150

 tgtttgttgt ggggaatatt ttaatactct tggactttag ggaggctatt 4200

 ttatgtgtca cttgctccta gttgtttcat tgtattagta attagcaaac 4250

 tgtcctggaa ccaagggttt ggtacttttg cctgattagc attccattat 4300

 ttatttgaaa tgctcagtgt ttgctcaaat ttggtgaaaa tatcttttga 4350

 agacatattc tctgagcctt aaaaatggct gctatcgaca gtactgtaag 4400

 atgcactgcc agtagatttg atacttttca tttcagtgta ggcagtaatg 4450

 ttttctaaga aagatttaga aatcagcaaa gtgtaacaat tgtgtttcat 4500

 ttatggaatg gaaaaactga agtgtcccat tcagaacact ttggaaaggt 4550

 tgtctgcatt aggggatgtt tctggaagca tcccttagag aagctgcctg 4600

 aggaatctcc ttgccaggtt gtaccagatt tttttttttc ttaaatgtat 4650

 tgtatatatt ttccttaaaa tgtcttcatt ggctgaatga ttcctatccg 4700

 tagtaatatt ttaggtactt gttggatttt taaaggaaga ttatttattt 4750

 tcagatttgc tgctataatt gaaaacctag taactggtcc tgttgattgt 4800

 gccttcatca ctgtttctct gtgccacgac cgttcatgtg tatttgaaat 4850

 aaagaagttt aaaaagccat gttgaattca agattccttc taataaaaat 4900

 aggtgaaact taatgagtag tattttatta ttaactttgt tgacactgag 4950

 acaatactag ttatccatt 4969

<210> 4313
<211> 95
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 29-88
<223> unknown amino acid

<220>
<221> Unsure
<222> 962-1140, 2856-2915
<223> Unknown amino acid

<400> 4313
 Met Asn Leu Pro Val Pro Arg Val Cys Ala Arg His Val Ala Gly
   1               5                  10                  15

 Gly Gln Ser Ala Ser Gly Cys Glu Thr Asn Tyr Ser Ser Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ser Ser
                  80                  85                  90

 Pro Leu Ser Leu Ser
                  95

<210> 4314
<211> 3081
<212> DNA
<213> Homo sapien

<400> 4314
 ctcgcagcag gaaccaggct ccaggcgccg gcgccggggc cgcggggagg 50

 aggcgacttc gctccctgcg gcgggcgcgg cccgggcgcc cgagcctcct 100

 cggccttgga gagcagcggc ggcggcggca ccccgggcgc ggcaatactg 150

 aacactgcgc agcttgcaga ggtctcctgg cagccctcat taggaattct 200

 gtctggcccc gatcagaata ctggagacga gaccacgaga ttgatgagtt 250

 tgccttggga gtcggtaaga aggtgaagcc aggggcgaac atgggtcaga 300

 aggtcactgg agggatcaag actgtggaca tgagggaccc cacgtacagg 350

 cccctgaagc aggagctcca gggtctggat tactgcaagc ccacccggct 400

 ggatctgcta ctggacatgc cccctgtgtc ctatgatgtc cagctgctgc 450

 attcatggaa caacaacgac cgatcgctca atgtctttgt gaaggaggac 500

 gacaagctca tctttcaccg gcatccggtg gcccagagca cggacgctat 550

 caggggcaaa gtcgggtata cccgtgggct gcacgtgtgg cagatcacgt 600

 gggccatgag acagcggggc acacacgccg tggtgggggt ggcgacggca 650

 gacgcccccc tgcactctgt cgggtacaca accctcgtgg ggaataacca 700

 cgagtcctgg ggctgggact tggggcgcaa ccggctctac cacgatggca 750

 agaaccagcc aagcaaaaca tacccagcct ttctggaacc agatgagaca 800

 ttcattgtcc ctgactcctt cctggtagcc ctggacatgg acgacgggac 850

 tctgagcttc attgtggatg gacagtacat gggagtggct tttcggggac 900

 tcaagggcaa aaaactgtat cctgtagtga gtgccgtctg gggccactgt 950

 gagatccgaa tgcgctactt gaacggactc gatcccgagc cgctgccgct 1000

 catggatttg tgccgtcgct cggtgcgcct ggccctgggg agggagcgcc 1050

 tgggggagat ccacacgctg ccgctgccgg cttccctcaa ggcctacctc 1100

 ctctaccagt gacgttcgcc atcataccgc cagcgcgaca gccacctggt 1150

 gccaactcac tgagccgcct gccgctgggg ccgccgcacc ctgcaccttg 1200

 gaccggcatc cgtagccatg gacagaggtc cctggtcttc cctcatcctc 1250

 cgtggctgcc tccatgggac aaggaccgat tccaacacag gctcctcttt 1300

 cccccttccc gacatcagca gaaggcagca tccctgcatg ccgtccgtat 1350

 acaacccctc tttgaaaaaa gacacagaga ataaactcct acgaaagccc 1400

 tacattgagc tccaatctgc tcggggtggg acgggtgctt cccacacctc 1450

 tgggagaagg ctgcagccac ctgggggtcc cagggtggtg ggggtggcag 1500

 gtggtaccac agctctgaga gcagatacca ggggtactaa gaggtgctta 1550

 gacaagggct ggtgcccggc ccagggtgcc cagcggggcc atgccatggc 1600

 agataaagct caggacgtca aaaactcacc atggacccca aggcagaaac 1650

 caagaactgt ctgcaggcaa ataagcaccc agcacccatc ctggctgccg 1700

 gtgccccgta ccctgtattt attcttttaa caataacaaa agccatttat 1750

 ttattccatc tagaaaggaa accctgtttc agtcccctct ctctggctgt 1800

 tctgttactt tccttccacc tgtgccctcc ctgggatatg tatgcctcgc 1850

 ccgccctccc tgggcacatg tgcacacgtg cccaggcaca agtatgtctc 1900

 tgggtccctt gccctgcagt ttccaggggg ctctgctcca agttccctag 1950

 cgggcccctc agggagaaat agcctcacgt gcaatctggg tgtcttcggg 2000

 ggcccgtctg gaagggctgc agcaattccc ctgtgtctcc aggtaaccag 2050

 ctaactcttg ggctcaggca cccttgcaca gggttgcatt tctttagtct 2100

 tctgtgggtc ttttgatgtg ggtttgattt tgcttttgct tttctagctg 2150

 agatttccca agtgcatcct cagaagctct gggtgtgcca gaggaccccc 2200

 agaactaaga agggagggcg agtgggtctc cattccccga gaagccaggg 2250

 gcagggtggg atggggaaga ccaggagcag agtcgagcct cacagaagcc 2300

 agcgcgggtc tctgctcagc accccagccg gggctctgga cccagggtaa 2350

 cagccccagt tcatcccaac ccctctcaga gcctcaagag gggtagctcg 2400

 gctgccggaa gagaggggtg ccctatccct ggcaacccct ccacgtagcg 2450

 taccccagca cctgccaccg cctttgccat ttctttgagc ttgaagttaa 2500

 ctctcttaga gtctaacttt ggttcatttc tgcacaggta caatagatga 2550

 ctttatttgt ttaaaatgtt taatatatat acatacatat atatatattt 2600

 gtctgtaaga attatgtttt aaacagctgc tgtagagtac ctttttttaa 2650

 gtaaatctta cagtggagta tattttttaa agcacaaaat tggtgccaag 2700

 actgggtgag aaatgtacat taccccctta ttattttgac ggtttttttt 2750

 ttcggggcag gggaccttac ctgtaagact tttaaagatt ttcctccctc 2800

 ctgtttcagg tgggtcacat tctgatgaat gtttcccttg tacagatccc 2850

 agcttatggc cttgacccag ccgtcctcac agatgccggg tgaccctcta 2900

 gctctctctg catctcccac cccccgacac cctgggaccc tcgaccccac 2950

 ccttctttcc taccagccca gagccttgtg gcttgtacag ttttgaaact 3000

 cccgttctat tttatgatgg ttgataatag tcagtaacct aataaaggaa 3050

 cgtttgttaa aatatcaaaa aaaaaaaaaa a 3081

<210> 4315
<211> 273
<212> PRT
<213> Homo sapien

<400> 4315
 Met Gly Gln Lys Val Thr Gly Gly Ile Lys Thr Val Asp Met Arg
   1               5                  10                  15

 Asp Pro Thr Tyr Arg Pro Leu Lys Gln Glu Leu Gln Gly Leu Asp
                  20                  25                  30

 Tyr Cys Lys Pro Thr Arg Leu Asp Leu Leu Leu Asp Met Pro Pro
                  35                  40                  45

 Val Ser Tyr Asp Val Gln Leu Leu His Ser Trp Asn Asn Asn Asp
                  50                  55                  60

 Arg Ser Leu Asn Val Phe Val Lys Glu Asp Asp Lys Leu Ile Phe
                  65                  70                  75

 His Arg His Pro Val Ala Gln Ser Thr Asp Ala Ile Arg Gly Lys
                  80                  85                  90

 Val Gly Tyr Thr Arg Gly Leu His Val Trp Gln Ile Thr Trp Ala
                  95                 100                 105

 Met Arg Gln Arg Gly Thr His Ala Val Val Gly Val Ala Thr Ala
                 110                 115                 120

 Asp Ala Pro Leu His Ser Val Gly Tyr Thr Thr Leu Val Gly Asn
                 125                 130                 135

 Asn His Glu Ser Trp Gly Trp Asp Leu Gly Arg Asn Arg Leu Tyr
                 140                 145                 150

 His Asp Gly Lys Asn Gln Pro Ser Lys Thr Tyr Pro Ala Phe Leu
                 155                 160                 165

 Glu Pro Asp Glu Thr Phe Ile Val Pro Asp Ser Phe Leu Val Ala
                 170                 175                 180

 Leu Asp Met Asp Asp Gly Thr Leu Ser Phe Ile Val Asp Gly Gln
                 185                 190                 195

 Tyr Met Gly Val Ala Phe Arg Gly Leu Lys Gly Lys Lys Leu Tyr
                 200                 205                 210

 Pro Val Val Ser Ala Val Trp Gly His Cys Glu Ile Arg Met Arg
                 215                 220                 225

 Tyr Leu Asn Gly Leu Asp Pro Glu Pro Leu Pro Leu Met Asp Leu
                 230                 235                 240

 Cys Arg Arg Ser Val Arg Leu Ala Leu Gly Arg Glu Arg Leu Gly
                 245                 250                 255

 Glu Ile His Thr Leu Pro Leu Pro Ala Ser Leu Lys Ala Tyr Leu
                 260                 265                 270

 Leu Tyr Gln


<210> 4316
<211> 6253
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2259-2541, 4832-5117
<223> Unknown base

<400> 4316
 aaaaaatgtt ttgtagagac agtctccctg ggcaatgtag tgagaccccc 50

 tgtctctaaa aaatataaat aaaaataaag gcatgttcct gaaagactgt 100

 caccttggaa agtgacaggc cctggcatta gcatgttgac acaccctttt 150

 cttcttactc agcaaaatac ttcgttttgg tttcttcttg tgttgctatt 200

 gagaaatttg tctgatcata tccttctgcc tttgtccccc aagaaatgcc 250

 ctactttatc cttttctttt tgtagttgag gagggctaga gaatcacaat 300

 taaaagtaag gaaatagcag ggttttgagg atccttgtcc cagccccaaa 350

 gctgaggaaa taagaataaa tgcttaatat agccttaatt ctagagcgca 400

 ccagccatga ggctgctttt cttgttgttt ttgattttta aaacatacag 450

 ctgtctggcc aggagcatct accatttcta gattattcag agtaatgagg 500

 ggaatggatg gattgctcca gtccacagat gagccacata atatgcaaat 550

 catataccca ttcatagcat ttgttaacat tgcttccctg ctcagctgct 600

 gattgaattc tgtgtgctta tataaattat gtcaaaaatt atactgcata 650

 attgaggtga cagctgttgc tgcagtgaca tgacagactg gaacaatgaa 700

 gcttttggtt taagtcagcc aggaaaatcc ttctgaatgg taatgtgatt 750

 gggcaagagc tcataaacca tacctcaagt gggtgggagt tttatctcta 800

 tattccttct ctctctgaag gaattaaagg cctagatcaa gtgctggata 850

 attgacaatt gcttgtactt aatctgatcg gtatctaaaa gaaggaaagg 900

 atggtcagga aacatttatc ataaatgtag ccaaggatat caattagggt 950

 agacaagaat aggacaaaaa taggccagag ctcctgagga ggtgatatgg 1000

 gtctcttgat ttgcagaaaa tgacagccta tccaagtggc ccagtgtatg 1050

 cctcccagta gcagtgggca tgtaaactgc agcgacctta tttttaaaac 1100

 caaaaaccta gtatgtggac aaagaacatg acaatatttg gtactgagat 1150

 tggttctgag aaacctgggg catgtggctg ctgtggttat aggtaatatt 1200

 taagacattc ataaaaatct gatattcttt taccgaaata accccagtat 1250

 catctactac ttaccatctg ttaatagact ttactctgtc ttttttgtct 1300

 tcggtttatt gtactgagtg ccgccaaaac aacttttgtt ctcttcctgc 1350

 ctacctgcag ctggttctat aggaatgtag ggagccagag gccagtattg 1400

 atttcagccc ttagcacaaa ggaaatcaga tgcctgcttc cagcatttgt 1450

 tagtgttgag tagatgttct tgccctagaa gaattacagc ctcaaacaga 1500

 aacctgtttc atggagcttt ctcccctcag aagagttaat agttaagagc 1550

 taagcactct taaacaccta agtctcaaat gctaaaaatt tatttttctt 1600

 gtgtttagtc ctctttcaag acatctttct aagcctttca gtaatcaaca 1650

 ttaaaagatc tccctttctt cagagttata gcacagcttt gcccagtaga 1700

 ggctaccaag gacagcttag cagccctttg attgctgggc tgggcagatg 1750

 gccttcaagt taagatcaaa tgccgggaaa atcagcctac atgggagcac 1800

 ccattttaaa cctggagaga accatgatgt tttcttcttc aaataacaat 1850

 ctagtttttt ttcccccagt actaaaattg tattgtcttt cagacaatat 1900

 aatttttatt taaaattgga acatactatc ttcatgcttt ctaagctaaa 1950

 tcttcattta gatttcactc ctcagtagat cccagagaag aagctatata 2000

 ggatccagat tcaaatttaa cagtgtcttc tactttttta gttatgtttt 2050

 ctatcaactc ctgctgcctt ttcaaatacg gatatttttc aggagactct 2100

 tctacttgtc cactgactgt attttttcct ttttgatccg tagccctggt 2150

 taaatggctg acatccttcc gtggatgatt cttggaggta gtctcagaat 2200

 tccaaagtga ttgtctgtct tcttcttgtc ttgatcctaa tgcagacatt 2250

 cacctctann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngtgcctggc 2550

 cacctctatt aaattttgtg gacaaaaata aaattgtcat tatttgtttg 2600

 ctctcatgga gcactttcag taatacaatt ttttttaaat tccagttgcc 2650

 ctctttgttg ctctgtcctc tgtaatacct gactttgcta aagacttgag 2700

 gggtggtttc agaggagggt caggtgatgg gaaggcagga tgagaaaagc 2750

 cctggacttg catgtttgag aaggcttcca accacatctt cactcagact 2800

 cttggaattc ctgtccccaa aacaagcttc tgttttttgc tcacaatgct 2850

 atatttctaa atttttcctg aattactgag aagcagtcat tagctttgtt 2900

 aagtttggtt tggggacatt gttggtatca aaaatcgaag tcttattcat 2950

 ttgatgtagg ccatgaatca tcaataactg gttgctggaa agcttgacta 3000

 ccatccactg gggtgctatt ttgagaagga tttttgggta tctttatagt 3050

 ctgcaattag ttgatgattg ctttctagtt tatcaactgc atttatattt 3100

 gcttttctgt tcatggaaaa tcctttattt gctggggttt ttgtttgttg 3150

 tttgtttttc ccacttacag caagtaaaag tggtctgagg ttatccttgt 3200

 ttttcttcgc ggtttgccat gtgtgaaagt agatttcctg ctattgatat 3250

 attctcatta tagacagaat agtggagaac agtgttgcca tggacaaaat 3300

 ccagttttgg tccactctgg ggagcatttg gacctgtggt gcttctaaca 3350

 attaaaagtc tagatggtcc ttgactgtcc cccagccata ctgcatacta 3400

 ctttgtgcat tctactttgt gtcattaatg aaagattggt tctgtccctg 3450

 taacttaggc atttattatt cttaactctt cattcctgtt ctgtagccac 3500

 ccagcagtcc attttcccta tgttcaggcc aaaccacagg gcattgggga 3550

 aggtttttgg gattttctta ttgagatttt gttgaatctg tagtttaccc 3600

 cagctttcct aaggtacagt gaggggttgg agggatctgt gtttggcccg 3650

 gggagcaatt gtctctacct taaggttcag ttttgagggc ataaaatact 3700

 actttgcaat gtcatgagaa caccattaga tctgaaatgt ggaaatggtt 3750

 tctcacaatt taaaggaaaa acccactttg cacccatgat cccatcattt 3800

 tggttgagat tttagaataa aaaatatagt gttgagatcc gtacttttgt 3850

 aatcagacca ccaagcatgc ctgtggcaag gcagagagga aaggtctgga 3900

 gccagtgtat tgcagtttca tgctaccttt acctgctaat cataaaaatt 3950

 atgttttcaa aagtagatga tactagcctt acacccaaaa acatgttctg 4000

 aattagatgc cccctcaccc aatttttatt aagctttcta aattccagcc 4050

 acattgctgt acatcaacat tggtttcatt caacagacat ttttttggcc 4100

 tgaagataca aggttcagaa agaggccatc cctgccctca aataactttc 4150

 atactggtgt atgatgaact gaccattaat agtttaagtg cttacaagct 4200

 atgtttctgt tcaaaaaaaa aatagtttgg tataataaat gctataaacc 4250

 aatacacatt tctgacttgg gggcagagac agactggctg atgttgtata 4300

 gtttgtagcc ctggagtaag aagttgacat taatttcggc ctatatgtgg 4350

 aaaagaccta taacattggg tgaactgagc cagctggcca tagaacacaa 4400

 gaacatattc caggaaataa atatagctgg agggttggaa atgctgttat 4450

 tactgagaga gaaaacaggt gagttgggat tgagaactcc tgattttcat 4500

 ccctggttta gattcttggc caaagtagtg gtagagttaa tctttgcttg 4550

 tggaaagcat taactatgtt gcagattcag ttgtgttaca ttattgtggg 4600

 ttctataaca acatattcct catggacact ttaccagagt tgctcacacc 4650

 tttttcaatt tctcatccct tttggaggaa tgaacatgag acttaactgc 4700

 ctttaagcct aaaacggaca tgctttccaa tgacaagaga ttttctaaag 4750

 agaagtcttg gagcacatct gttaatacct gagcatctac tctgagcagt 4800

 gcagttttat tcaatactgg agagagggtg annnnnnnnn nnnnnnnnnn 4850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 4900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 4950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5050

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5100

 nnnnnnnnnn nnnnnnncgg gccgagaggg tgatttctaa gcagagaatt 5150

 gtatcagtta tgtggaaacc tttgccagaa atacatatac cttgtatatt 5200

 aaatctgagt ctcagattta atcatcgaag cgtagctggg ttaagaaaca 5250

 gtctgatcgt aaggatgttg tcgattctga cccatggatg accacaagaa 5300

 aaagatattt atttctgcct ggataattga gagttgacta actttggaag 5350

 tcagaattcc caggaattag agtaactgct ctggaaagtt aaagtgtgaa 5400

 gttttttaga tagtttcata aaaacaattc tggtttcttt ttgcttgtgc 5450

 tgactttctt ggattttaat ctacctcatc ttgtcttttt agagttactt 5500

 caacttgtca ctttaacatt gtgcttgact ttggttgttt tctaagatgg 5550

 aatttttcct gttcattgac agcttgttct cttgcctttt cattctgatc 5600

 ctcatttcat ctaacatcat ctcatattgc tcctctgtca agagaaatgt 5650

 tttaaaatag tttaaagtct tgttttatgg gaagaaagtg atcctccaat 5700

 gctatttgtt tctgaggtca gtaagagaag gagttaaaac aaggcagtgg 5750

 ggaagggaat gaatcctgca ctggaggcaa aagctgacaa ggaaagagcc 5800

 attaattaag acaatttcaa agtcaactga ttgtgatcat taatgtcaca 5850

 atagatcaaa acctaattat cacagcctag gtaagagcca tcagtattaa 5900

 tcggaaaatc taataggaaa ctattatcaa gaaattaggc caaattgaat 5950

 gcagtgaact ttttatcttg gcattctcta tttttttgtg atgtcccctg 6000

 gcattggcag gtgtgaccct aacagtcgat tcaaggccaa gtggtcagtt 6050

 tgtcagcctt ttttaaggga tttcttttta tttttaggaa ttccaaacag 6100

 agttaaccta aactgtcatt gccaaaagat cagtcttaaa ctttcttagc 6150

 acctgtacct gtttaatgtg atcagctatc agtgaggaaa aaaaaaaaaa 6200

 tctattcagg tctgggaagg gtcccggtac ctagagtatc catatggaac 6250

 ctt 6253

<210> 4317
<211> 113
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 7-101
<223> unknown amino acid

<220>
<221> Unsure
<222> 2259-2541, 4832-5117
<223> Unknown amino acid

<400> 4317
 Met Gln Thr Phe Thr Ser Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
   1               5                  10                  15

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Cys Leu Ala Thr
                  95                 100                 105

 Ser Ile Lys Phe Cys Gly Gln Lys
                 110

<210> 4318
<211> 3772
<212> DNA
<213> Homo sapien

<400> 4318
 agcgggataa gttggcgcgt cacctagacg tcagcctctt acctctcgga 50

 cgtcccgtcc caggagcaaa actctagtga ctttgggccc gcccccgtga 100

 gagtggaggg cggccgatga gggcggttct gaagggaaca agaccaatga 150

 gacgagcccg gggcggggcg cggggccgga gggtggggcg ggtggcggcg 200

 gtggcagtcc gaggtctggc tccgcgcagt atatgacagt acgtcagcag 250

 cgggatggcc ctagcagtgg cggcggctgc agaagcccaa gcagccgcgg 300

 ccgcagtgga ggctagagcc ggagcggcgg cggcggcggc accccgggga 350

 gtttaagatg gcggcggggg ggacaggggg cctgcgggag gagcagcgct 400

 atgggctgtc gtgcggacgg ctggggcagg acaacatcac cgtactgcat 450

 gtgaagctca ccgagacggc gatccgggcg ctcgagactt accagagcca 500

 caagaattta attccttttc gaccttcaat ccagttccaa ggactccacg 550

 ggcttgtcaa aattcccaaa aatgatcccc tcaatgaagt tcataacttt 600

 aacttttatt tgtcaaatgt gggcaaagac aaccctcagg gcagctttga 650

 ctgcatccag caaacattct ccagctctgg agcctcccag ctcaattgcc 700

 tgggatttat acaagataaa attacagtgt gtgcaacaaa cgactcgtat 750

 cagatgacac gagaaagaat gacccaggca gaggaggaat cccgcaaccg 800

 aagcacaaaa gttatcaaac ccggtggacc atatgtaggg aaaagagtgc 850

 aaattcggaa agcacctcaa gctgtttcag atacagttcc tgagaggaaa 900

 aggtcaaccc ccatgaaccc tgcaaataca attcgaaaga cacatagcag 950

 cagcaccatc tctcagaggc catacaggga cagggtgatt cacttactgg 1000

 ccctgaaggc ctacaagaaa ccggagctac ttgctagact ccagaaagat 1050

 ggtgtcaatc aaaaagacaa gaactccctg ggagcaattc tgcaacaggt 1100

 agccaatctg aattctaagg acctctcata taccttaaag gattatgttt 1150

 ttaaagagct tcaaagagac tggcctggat acagtgaaat agacagacgg 1200

 tcattggagt cagtgctctc tagaaaacta aatccgtctc agaatgctac 1250

 aggcaccagc cgttcagaat ctcctgtatg ttctagtaga gatgctgtat 1300

 cttctcctca gaaacggctt ttggattcag agtttattga tcctttaatg 1350

 aataaaaaag cccgaatatc tcacctgacg aacagagtac caccaacact 1400

 aaatggtcat ttgaatccca ccagtgaaaa atcggctgca ggcctcccac 1450

 tgccccctgc ggctgctgcc atccccaccc ctccaccgct gccttcaacc 1500

 tatctgccca tctcacatcc tcctcagatt gtaaattcta actccaactc 1550

 ccctagcact ccagaaggcc gggggactca agacctacct gttgacagtt 1600

 ttagtcaaaa cgatagtatc tatgaggacc agcaagacaa atatacctct 1650

 aggacttctc tggaaacctt accccctggt tccgttctac taaagtgtcc 1700

 aaagcctatg gaagaaaacc attcaatgtc tcacaaaaag tccaaaaaga 1750

 agtctaaaaa acataaggaa aaggaccaaa taaaaaagca cgacattgag 1800

 actattgagg aaaaggagga agatcttaag agagaagagg aaattgccaa 1850

 gctaaataac tccagtccaa attccagtgg aggagttaaa gaggattgca 1900

 ctgcctccat ggaaccttca gcaattgaac tcccagatta tttgataaaa 1950

 tatatcgcta tcgtctccta tgagcaacgc cagaattata aggatgactt 2000

 caatgcagag tatgatgagt acagagcttt gcatgccagg atggagactg 2050

 tagctagaag atttatcaaa ctagatgcac aaagaaagcg cctttctcca 2100

 ggctcaaaag agtatcagaa tgttcatgaa gaagtcttac aagaatatca 2150

 gaagataaag cagtctagtc ccaattacca tgaagaaaaa tacagatgtg 2200

 aatatcttca taacaagctg gctcacatca aaaggctaat aggtgaattt 2250

 gaccaacagc aagcagagtc atggtcctag aactctgctt ggaccagaag 2300

 atgtgaataa acttaagctt atttatttaa aattccaaat gagttgctct 2350

 agattctaaa aaggtgaaac tttggctgtt gaaagtttca gtattagtaa 2400

 acttgagtta ctttttcttt tccattttac tttgcttccc tgcatttcga 2450

 agctgctctt tctggtcctc cccaccaccc cacccccaag acttgtgttt 2500

 gttaatagaa ataatttttt taggtattgg ggatccattg tctatatttc 2550

 aaatcagttt tttttcctca aaaacttgtg tttgttatta gaaatgattt 2600

 tttagatatt ggggatccag tgtccacact taaaagttgt atgtgtttaa 2650

 aaaacaacaa cagtaatgtg caaggtgaaa tgcttttgga taaacgtaag 2700

 cctattttct gacgtttctt aatgcaaact ctttgcctta aatggtagaa 2750

 tatttagaaa tttgcacaaa attaaaaaaa taaacattgt cttggagggt 2800

 taaaaaatag aaaggtgtat gtgtatagat tcacatacac atatgtatat 2850

 acaggctgac ttgatctaga acattaaatc cgccctgcaa gttaaccccc 2900

 cattgcaatg gttgccttaa ggtgtttgct agttgtgtac atagtgtggt 2950

 taatcattag ctacactgct tcccacttga ttagagcaat gggaagcata 3000

 ctgtggccta ccagcatctg gaagtgtgtg ctcgatctgt atgtgtgcag 3050

 aggtggtgtg gatgtgagcg tgcatgaagg aaaaaaagct gctactccta 3100

 gtaggccaaa cgctcaggtt aaacaactga cgagtgttac tgtagggtgt 3150

 ttttttgttt ttttgttttt tttcttctat caaattgcta cttttgttgt 3200

 ggaagacaaa agcatttcca tttcaacgag tttgtcagct ttattaatgt 3250

 tgggcaaaaa ttgatatgtc atgaaaatga aacagatcta tagttttggg 3300

 acaaaattat aaaatgaaat gtgtaggtaa cctatttata tactgctata 3350

 aagtattttt tgaagagaga tatgcaaaga agctattacc tacataagag 3400

 gtatatttaa agattttttt tttttcatcc tggtgccagg aatataaaaa 3450

 agagtggata tatttaacca taacatactg tgattcatca aacagcacaa 3500

 actttcattt catggagttt atctgttgac attgatttaa actgtcactt 3550

 gttttatcat gtgggaacat aagttatgtg gtcaaaaata taaggatttt 3600

 gaattaatgt tgattcaagt tgtattgtct tattgtattg tcttttcaaa 3650

 gtgctgccag ttgaaaaggg aagcattatg tttacaaatc tgttttgaaa 3700

 tgtttgccaa aattttggta gtgtctttaa taaagatgtt tgtctccagc 3750

 atccagaaaa aaaaaaaaaa aa 3772

<210> 4319
<211> 640
<212> PRT
<213> Homo sapien

<400> 4319
 Met Ala Ala Gly Gly Thr Gly Gly Leu Arg Glu Glu Gln Arg Tyr
   1               5                  10                  15

 Gly Leu Ser Cys Gly Arg Leu Gly Gln Asp Asn Ile Thr Val Leu
                  20                  25                  30

 His Val Lys Leu Thr Glu Thr Ala Ile Arg Ala Leu Glu Thr Tyr
                  35                  40                  45

 Gln Ser His Lys Asn Leu Ile Pro Phe Arg Pro Ser Ile Gln Phe
                  50                  55                  60

 Gln Gly Leu His Gly Leu Val Lys Ile Pro Lys Asn Asp Pro Leu
                  65                  70                  75

 Asn Glu Val His Asn Phe Asn Phe Tyr Leu Ser Asn Val Gly Lys
                  80                  85                  90

 Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile Gln Gln Thr Phe Ser
                  95                 100                 105

 Ser Ser Gly Ala Ser Gln Leu Asn Cys Leu Gly Phe Ile Gln Asp
                 110                 115                 120

 Lys Ile Thr Val Cys Ala Thr Asn Asp Ser Tyr Gln Met Thr Arg
                 125                 130                 135

 Glu Arg Met Thr Gln Ala Glu Glu Glu Ser Arg Asn Arg Ser Thr
                 140                 145                 150

 Lys Val Ile Lys Pro Gly Gly Pro Tyr Val Gly Lys Arg Val Gln
                 155                 160                 165

 Ile Arg Lys Ala Pro Gln Ala Val Ser Asp Thr Val Pro Glu Arg
                 170                 175                 180

 Lys Arg Ser Thr Pro Met Asn Pro Ala Asn Thr Ile Arg Lys Thr
                 185                 190                 195

 His Ser Ser Ser Thr Ile Ser Gln Arg Pro Tyr Arg Asp Arg Val
                 200                 205                 210

 Ile His Leu Leu Ala Leu Lys Ala Tyr Lys Lys Pro Glu Leu Leu
                 215                 220                 225

 Ala Arg Leu Gln Lys Asp Gly Val Asn Gln Lys Asp Lys Asn Ser
                 230                 235                 240

 Leu Gly Ala Ile Leu Gln Gln Val Ala Asn Leu Asn Ser Lys Asp
                 245                 250                 255

 Leu Ser Tyr Thr Leu Lys Asp Tyr Val Phe Lys Glu Leu Gln Arg
                 260                 265                 270

 Asp Trp Pro Gly Tyr Ser Glu Ile Asp Arg Arg Ser Leu Glu Ser
                 275                 280                 285

 Val Leu Ser Arg Lys Leu Asn Pro Ser Gln Asn Ala Thr Gly Thr
                 290                 295                 300

 Ser Arg Ser Glu Ser Pro Val Cys Ser Ser Arg Asp Ala Val Ser
                 305                 310                 315

 Ser Pro Gln Lys Arg Leu Leu Asp Ser Glu Phe Ile Asp Pro Leu
                 320                 325                 330

 Met Asn Lys Lys Ala Arg Ile Ser His Leu Thr Asn Arg Val Pro
                 335                 340                 345

 Pro Thr Leu Asn Gly His Leu Asn Pro Thr Ser Glu Lys Ser Ala
                 350                 355                 360

 Ala Gly Leu Pro Leu Pro Pro Ala Ala Ala Ala Ile Pro Thr Pro
                 365                 370                 375

 Pro Pro Leu Pro Ser Thr Tyr Leu Pro Ile Ser His Pro Pro Gln
                 380                 385                 390

 Ile Val Asn Ser Asn Ser Asn Ser Pro Ser Thr Pro Glu Gly Arg
                 395                 400                 405

 Gly Thr Gln Asp Leu Pro Val Asp Ser Phe Ser Gln Asn Asp Ser
                 410                 415                 420

 Ile Tyr Glu Asp Gln Gln Asp Lys Tyr Thr Ser Arg Thr Ser Leu
                 425                 430                 435

 Glu Thr Leu Pro Pro Gly Ser Val Leu Leu Lys Cys Pro Lys Pro
                 440                 445                 450

 Met Glu Glu Asn His Ser Met Ser His Lys Lys Ser Lys Lys Lys
                 455                 460                 465

 Ser Lys Lys His Lys Glu Lys Asp Gln Ile Lys Lys His Asp Ile
                 470                 475                 480

 Glu Thr Ile Glu Glu Lys Glu Glu Asp Leu Lys Arg Glu Glu Glu
                 485                 490                 495

 Ile Ala Lys Leu Asn Asn Ser Ser Pro Asn Ser Ser Gly Gly Val
                 500                 505                 510

 Lys Glu Asp Cys Thr Ala Ser Met Glu Pro Ser Ala Ile Glu Leu
                 515                 520                 525

 Pro Asp Tyr Leu Ile Lys Tyr Ile Ala Ile Val Ser Tyr Glu Gln
                 530                 535                 540

 Arg Gln Asn Tyr Lys Asp Asp Phe Asn Ala Glu Tyr Asp Glu Tyr
                 545                 550                 555

 Arg Ala Leu His Ala Arg Met Glu Thr Val Ala Arg Arg Phe Ile
                 560                 565                 570

 Lys Leu Asp Ala Gln Arg Lys Arg Leu Ser Pro Gly Ser Lys Glu
                 575                 580                 585

 Tyr Gln Asn Val His Glu Glu Val Leu Gln Glu Tyr Gln Lys Ile
                 590                 595                 600

 Lys Gln Ser Ser Pro Asn Tyr His Glu Glu Lys Tyr Arg Cys Glu
                 605                 610                 615

 Tyr Leu His Asn Lys Leu Ala His Ile Lys Arg Leu Ile Gly Glu
                 620                 625                 630

 Phe Asp Gln Gln Gln Ala Glu Ser Trp Ser
                 635                 640

<210> 4320
<211> 2686
<212> DNA
<213> Homo sapien

<400> 4320
 gcgcgagagg acgtgctctg ccagccagtg ggaaggcagg ccgcgcgcgc 50

 gggagcgcgg gaggatcggc ggctcgcggt cactggtccc tggctcggtt 100

 ccccgcaccc cggggctcac acttacccgc gcggaggagc agcggccggg 150

 tgtccacccc catcctgcgc ccagtctcct cgattcccct cgctctgagc 200

 cgggagagcc gaacagctga agagagttca ctgactcccc agccccaggt 250

 gggccttgtg cacatcatga ccagttttga agatgctgac acagaagaga 300

 cagtaacttg tctccagatg acggtttacc atcctggcca gttgcagtgt 350

 ggaatatttc agtcaataag ttttaacaga gagaaactcc cttccagcga 400

 agtggtgaaa tttggccgaa attccaacat ctgtcattat acttttcagg 450

 acaaacaggt ttcccgagtt cagttttctc tgcagctgtt taaaaaaatt 500

 caacagctca gttctctcct ttgaaataaa aaatatgagt aaaaagacca 550

 atctgatcgt ggacagcaga gagctgggct acctaaataa aatggacctg 600

 ccatacaggt gcatggtcag attcggagag tatcagtttc tgatggagaa 650

 ggaagatggc gagtcattgg aattttttga gactcaattt attttatctc 700

 caagatcact cttgcaagaa aacaactggc caccacacag gcccataccg 750

 gagtatggca cttattcgct ctgctcctcc caaagcagtt ctccgacaga 800

 aatggatgaa aatgagtcat gaacacagaa agtctaagag gagaaatatg 850

 atggatgaag agctctgtag atgctgtata gacactaaat aagagttgat 900

 tagggtagta tattatagtc atctgttatg ctgtgaaatt tggaattcag 950

 tattatcatt ttgaagtctg taaattgtgt tagtcattaa cttagtcacc 1000

 tgttgtattc tggatctaca caaaattatt ttaactgctc ttattaatct 1050

 gtgaggatta atatacaaaa agtatccttt gagatgaagt cgtgttctca 1100

 aaataaggtt atattatttt ctttttctgc ttgattttca tcttgtgttt 1150

 tgctttgttt ttgtaaggaa ccatctcttg gtttggtcac atcagttcac 1200

 aacagccatt tgttttcaag gtcaaggctc caggcaggtt gttactggtg 1250

 tttgcagcct gtcagtactt gcagtactgg aataggttct aggctagtgt 1300

 ctgcgcgtca ctgtggtttt agcatgggag gacttatttg agaaatacta 1350

 ccttactttt ctatgatttc tttttacaga gttatagtgt gtttactcct 1400

 aagatgacag ttctctttgt ctatattcag catctaagac aaatatttaa 1450

 acattttaaa gaaccactgt gttaagttta ggattattta cttaccaaat 1500

 tagaagtttg acttttatgt gttatacaca atcttaaaat ttcacgaatt 1550

 caccttttta atagtatcca tgtacataat aaaatcaaag tttaattagc 1600

 cattttcttt gaattttttt ctaaataagg gaaataactg ttcttgggcc 1650

 actttacaga gataaatgta tgtgaatgtt tatgataaac gcttaaatat 1700

 ttctaaaata ttaacttcaa aaaagtcttt ttcagttctt aaataaaaat 1750

 ttatttattt aagatactta ttcgacttat cttaactaag gtagctatga 1800

 atgttaagta gatgaggtaa ccattcagtt aagttaaatt gtagcattgc 1850

 caggtagtga ggctcactgt acaattttcc aggtaaatga aatttcctgt 1900

 agtaagaggt ccgtattttt gtaacagcct tttaaaaatg cttttgggaa 1950

 ccctccagcc tcttaccaaa agaggcttta aacctcatct tgattcagac 2000

 tgtcagtcta ttcctgggca gtagtatgtg atgtccagca ccctaacccc 2050

 gactccccag ccctgggact attccagtag agtgaaatat ttgtccctgt 2100

 acaaagtggc ctgaatgact gttggagttc ctgtgtctgg ttttcctgtt 2150

 tattccctgt gatgcccaga gtaatggccc atccaaagat gtccagatgt 2200

 ccatgtgcta gtctccagaa cttgtaactg tgttgttatg tggcaaaggg 2250

 gaatgaaggc tgcagatgga agtaaaatag attatgctgg attatctggg 2300

 tgtgcccaat tgatcaccgg atccgtaaaa gtggaagaga ggcagatcag 2350

 gatgtcagcg tgatgaggtg tgagacagac ttgacttgct gttgctggga 2400

 ggaaggggag gtcatgagcc aaggaatgtg gacagtctct tgaagctgga 2450

 aagtgtgcat tggacatctg gaagccagaa aagacaaaga aatatccaga 2500

 aaggaacaaa gtcttgtgga caccttgatt ttggtccagt gagaatatgt 2550

 ttgacttgtt aacctacaaa actttatgat gataaatttg tgttggtcgt 2600

 aagccactaa atcacagtaa tttgttatag cagcagatag aaaactaata 2650

 tactcccttt aatataaaaa aaaaaaaaaa aaaaaa 2686

<210> 4321
<211> 4035
<212> DNA
<213> Homo sapien

<400> 4321
 gggatcaggg cggggccctg agcgccgcca tgcttttgta cggcaggatc 50

 gcaaagcacg ccgggaccgg ttggtttggt tttgaagacg tggatggcgg 100

 gaattctcgc ttctggcctg ggtgttttag ctcacttgga aaggctagag 150

 acccaagtga gcagatcccg taaacggtct gaagagctgc agagcgtgca 200

 ggcccaggaa ggtgctcttg gaaccaagat tcataaacta aggcgtctgc 250

 gagatgagct gagggctgtg gtgcggcacc ggcgagccag cgtgaaagca 300

 tgtattgcca atgtagaacc caaccaaaca gtggagatca atgagcaaga 350

 agcattggaa gagaaattgg aaaatgtgaa agccattctg caggcatatc 400

 attttacagg cctcagtggt aaactgacca gccgaggagt ttgtgtctgc 450

 atcagtactg cttttgaggg gaacctattg gattcctatt ttgtggacct 500

 tgtcatacag aaaccactcc ggatacatca ccattcagtc ccagtcttca 550

 ttcccctgga agagatagct gcaaaatatt tacagaccaa catccagcac 600

 ttcctgttca gtctctgcga gtacctgaat gcttactctg ggaggaagta 650

 ccaggcagac cggcttcaga gtgactttgc agccctcctg actgggccct 700

 tgcagagaaa cccactgtgt aacttgctgt catttactta caaactggat 750

 ccagggggtc agtccttccc gttctgtgtt agattgctgt ataaggacct 800

 cacagcaact cttcccactg acgtcaccgt gacatgtcaa ggagtggaag 850

 tattatccac ttcatgggag gagcaacgag tatctcatga aactctgttc 900

 tgtacgaagc ccttgcatca agtgtttgcc tcatttacaa gaaaaggaga 950

 aaagttggat atgagtctgg tctcctaata gattgttttc actgcactgg 1000

 gagcacatca gagaaataaa tcccccctcc cctgccaggt gaaaggaaat 1050

 attgcacttt ctgttctcat gactaagggg acaggagttc cagaagaacc 1100

 tttcaagatg atcaggaaca ccaggacgag ggccgtctca cctcactcgg 1150

 accacatgga gacctccctt caaaatggga gccatgtcct gccccaccaa 1200

 gccctgtctg aagtggagct tccccgcctg tgctccctcc acagtcccgg 1250

 aaagcccagc ggcaaaggca gctttgtccc agctctgcca ccctcctgct 1300

 cacagtggtc agggcccctc aggggcaagg acggcaggga ttggaacgag 1350

 ggctctggaa ggactgttca gccctatgcc taagacccct atgctgggga 1400

 cactacaggc acacagagga atagcagggc caccctcaga gctcacacat 1450

 ccacgaacaa atgaaggctg aggaggtttc taaacctaaa gtccatgagt 1500

 gtgcacttca atccaggaag gtcgggactt ccttcagttt caaaaaataa 1550

 attctccctt ccggtttgga ctgttgcagg ctcgaggcca ttcaggagtt 1600

 gtccaccacc tggtggggca gtgtgacaga ggggccattg gggaaggtgg 1650

 ctagcttatc ccgccccttc aagaagaagg tcagcagctc ccccttcccc 1700

 ttcacaaaga tggggcctcg cctcacaaag cggaagccgt actctcggag 1750

 gatgacttgg gtttcttcta ccacctggag agggaggggg agcaagaacg 1800

 tggcgttacg gggggagcct agactgaggg cgggtggggg ctttgggtgg 1850

 ttggagccga gcactgatcc atgggtccca agcagtatgg gacactcccc 1900

 aaacctccca gggccaagcc cttccacccg tggcgagcag cgggtgggaa 1950

 ggagaaccct ggagtgactg gctgggggcc tcctctcatc cagagacttc 2000

 tctcctagga tggccatggt cacctgggtg gcagcactgt tacctggaaa 2050

 ctgccactgc ctgctcttct gtccctttgc ccctttcgtg gagcttttct 2100

 gccagacgcc actgagacag atcacaaggt attagaaggt tcatacccaa 2150

 aggtaggcca tatgcatcta gaacttcagc ccagattttg tggatgggtg 2200

 gaagtgtttc ttcctgtgct gaggctagct attgcagaga ttcttttcca 2250

 cttgccccac gtctctgcct ctggacttac cgttcagggc cagggtggga 2300

 ggcaggggca cgtgggaaag cactgttccg gttttgttct catgccgagt 2350

 ctgagcacgt gccagctgtg ccactggaca tacctgaatg ttgcccatga 2400

 cccccgtgga ctccatcctg ctggctacat tgactgtatt gccccagatg 2450

 tcgtagtgtg gtttccgggc tccgatgacc ccagccagaa ccccgccttt 2500

 gttcatgcct agggtagagg cataaagttc agcacagcca caggccacac 2550

 cttgttatgg gcctcagaag ccatctcctc tccagacctg taccacaaag 2600

 ctcctaatgt aacacatcat tgtcctcatt caacttggct gtatgctatt 2650

 ggagggtgga aatcacatct cctgtttatc cgtgtgcttg ttaggtgtca 2700

 gccgccaccc cccccccata tgcagattta ctcggcatgg tagtggccag 2750

 cttctaacac agctggtatt tcaagtctcc tgggacctca ctcaggaatg 2800

 ataccccctc agtagaagca gcaggtgatc ttaactcctt tcaaagagca 2850

 ggcctgtctg ggaagccatg tcctcagcag gcacagcaac ccctctggaa 2900

 atggatcaca aactcacttc tcagccaggc aggccaagct tctgttgtaa 2950

 cagtaggcac agtatagtcg gatcatcata tcagctgggt ttttggttta 3000

 gtcatctaga gtcgtctgga ctaaaggtct ttcaggtctc cttgccctgt 3050

 gagtgcgtga acctccccac ccgaattgcc tcagttgtcc tgagcctcat 3100

 gtctctcctg gtggtgggcc aggcccctgc atgggaaggg agcctgctgc 3150

 ggggcaggcc agctgggggt gctcacctat gcgcagcatg aagttattga 3200

 aggactggtt gttgatgttg gtgagcgtat ccttcatggc cagcgcgaag 3250

 tcggccaggt cagccaggtg ctgccagcgc tctctctcgg acttgtcttc 3300

 ctgtgccagg ggaccgtgga gaaagtgtca ggagccgctc actgcagcag 3350

 cctgctctgc tgccttccct ggcagtgttc tgggggtgga ttccctacac 3400

 ctagatgttc aaggccttac ttttcctccc acaaaggagt cgcagccacg 3450

 ctagctctga cttgccactg tgacaaagtt cacgtagcag gtctaggcaa 3500

 agactgggca attgagcaga ggagacggac ctgtgagtct gaccacgagg 3550

 cggacccctt caccttggct gggcctggtc ctggtcctta ggttttgtca 3600

 ggttgtcctt gtttggatcc ctcaactagg tgataagcac tggaggggga 3650

 tgacccgcct tggacgtgtt tctttaacct catccatata atagggccgt 3700

 gggatggttg tagaggtaaa gcaggatgat ggtgttttaa gaccagagct 3750

 tgggaccagg gctcctacac ctaattttct ctcctggtag ctgaacaaag 3800

 gtctaaatta gcttaacaaa agaacaggct gccgtcagcc agagttctga 3850

 aggccattct ttcagtttcc cttgttgaca attgctctcc agttcctatg 3900

 aaagcacaga gccttagggg gcctggccac agaacacaac catcttaggc 3950

 ctgagctgtg aacagcaggg ggttgtgtgt ctgttctgtt tctctgcttg 4000

 ccgaactttc tcaataaacc ctatttctta tttat 4035

<210> 4322
<211> 294
<212> PRT
<213> Homo sapien

<400> 4322
 Met Ala Gly Ile Leu Ala Ser Gly Leu Gly Val Leu Ala His Leu
   1               5                  10                  15

 Glu Arg Leu Glu Thr Gln Val Ser Arg Ser Arg Lys Arg Ser Glu
                  20                  25                  30

 Glu Leu Gln Ser Val Gln Ala Gln Glu Gly Ala Leu Gly Thr Lys
                  35                  40                  45

 Ile His Lys Leu Arg Arg Leu Arg Asp Glu Leu Arg Ala Val Val
                  50                  55                  60

 Arg His Arg Arg Ala Ser Val Lys Ala Cys Ile Ala Asn Val Glu
                  65                  70                  75

 Pro Asn Gln Thr Val Glu Ile Asn Glu Gln Glu Ala Leu Glu Glu
                  80                  85                  90

 Lys Leu Glu Asn Val Lys Ala Ile Leu Gln Ala Tyr His Phe Thr
                  95                 100                 105

 Gly Leu Ser Gly Lys Leu Thr Ser Arg Gly Val Cys Val Cys Ile
                 110                 115                 120

 Ser Thr Ala Phe Glu Gly Asn Leu Leu Asp Ser Tyr Phe Val Asp
                 125                 130                 135

 Leu Val Ile Gln Lys Pro Leu Arg Ile His His His Ser Val Pro
                 140                 145                 150

 Val Phe Ile Pro Leu Glu Glu Ile Ala Ala Lys Tyr Leu Gln Thr
                 155                 160                 165

 Asn Ile Gln His Phe Leu Phe Ser Leu Cys Glu Tyr Leu Asn Ala
                 170                 175                 180

 Tyr Ser Gly Arg Lys Tyr Gln Ala Asp Arg Leu Gln Ser Asp Phe
                 185                 190                 195

 Ala Ala Leu Leu Thr Gly Pro Leu Gln Arg Asn Pro Leu Cys Asn
                 200                 205                 210

 Leu Leu Ser Phe Thr Tyr Lys Leu Asp Pro Gly Gly Gln Ser Phe
                 215                 220                 225

 Pro Phe Cys Val Arg Leu Leu Tyr Lys Asp Leu Thr Ala Thr Leu
                 230                 235                 240

 Pro Thr Asp Val Thr Val Thr Cys Gln Gly Val Glu Val Leu Ser
                 245                 250                 255

 Thr Ser Trp Glu Glu Gln Arg Val Ser His Glu Thr Leu Phe Cys
                 260                 265                 270

 Thr Lys Pro Leu His Gln Val Phe Ala Ser Phe Thr Arg Lys Gly
                 275                 280                 285

 Glu Lys Leu Asp Met Ser Leu Val Ser
                 290

<210> 4323
<211> 1896
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 98
<223> Unknown base

<400> 4323
 attgttctat tgatggcagg taatcatcac tcttcactag ctgagcattc 50

 ggtccactaa cctgagtcat atccggcact ggtttctcta gaaagggntc 100

 cgacggggaa tgctgatgca caggcacttt ctgcggggtg ttctggggtg 150

 atgggtggag ctgtgcccaa ggctggtgat gagggtgtgg aggtgaagac 200

 tggtggtgca agcccgggtg aggctgcagt ggaggacagg ttggaactgc 250

 tgaaaagatg gctgttgacc aggatgttgt tggccaggta tcagtcgttc 300

 ctggattgct tgtgggtctc caaggccaac accaggacaa ccatttggcc 350

 tcatgtgccc agtcaattcc cttggtgccg aggacatgcc tataaatgga 400

 cgagactgct gcatgtttct ggggcccata ttcctctgtc cgattcccat 450

 ggcaccaggg ggctggtgag atggctgagg atggggcata tttggataac 500

 tgccaacttc cattggtatc ccagcacttc ccggcctgac ttgtggagga 550

 ggagtgcctg ctggattact cattgctttc atgggtgaca tgggaggtgg 600

 agaggcataa gttccctgag gctgtgaagg atgcatagtt tgtgtgttca 650

 tttggttaag tgagccactg gggtggatgg gctgctggtg cattagtcct 700

 tgaccactgt ttgatgggaa tcctacagca ttggggtatc ttggtacgga 750

 ctgattcatt ggagtattat ttgtaaggcc taaattttga ttcatccctg 800

 tattgttaac taatccctga tttaggttac tgtaaggata tcgagaatac 850

 tgccctgagt tgtttatagt aggagagggg actgtctggc tccgagaact 900

 aaagttaagg gtttgcggcc taacagcccc ttgttgggga ggattcgggg 950

 agaatctggg actgtgggca acggattctc catggagagc agtagagggg 1000

 tggtgatgga actgctgcac cgagtgacgc aaggaaggtg ccatgctggg 1050

 actctgctgg ggcacgtggg acaagtggcc aggtcctgag gtggcaataa 1100

 aaggatttcc ctgattgagg ccctcttggc cttgggaaaa ctggctcatc 1150

 ctctgctgtg gctgaccatg ctgctgcatg gaaaaatccc cacgtgccat 1200

 atagctgccc atctgctgca tgtgctgagg gtggccctgt gcagggggcc 1250

 ccgacggagc cggctgcggt ggctgcggct gtggctgctg ctgctggtag 1300

 ggggctcgta tctggtctgg tacctgaaca gccctggggc cccacatgga 1350

 gctgctgtcc acaaaggatt gcccatgcct ctcattctgc atgccagggt 1400

 agacacccat ctgaccgcca ccactgccac catggggcac ctgaggaacg 1450

 ggaggggtgt gatactgcga gtgcggagac gcgagtccgt tcccaggggt 1500

 gttgctcatc attctgttcg gctgatccat cagatgcatc ttttgttgtt 1550

 catactgatt atagtgatca aaatgtgtca gctttgtttg attttgatta 1600

 gttgaaggat gatgaaggga tggctgtaaa gaggcaaagc cttggtctat 1650

 tggcatttgc tgacccatag gatttactgg attttccggg taaccacatt 1700

 ctccgaggcc ttcaagacct tcactgaaaa tattcccatc ctcgccaaaa 1750

 agactcatca ttcctggatc tgccatctta ttccaacaca cggctcctcc 1800

 aaaccacagc tcaggagctt gcctgtgctt cacttcactg aggtgtttgc 1850

 cctcaaagcc tatatgacca atccctaatt gctgtcctga tgatga 1896

<210> 4324
<211> 2495
<212> DNA
<213> Homo sapien

<400> 4324
 gcggccgctg cctcctgctc gccccggcgc ccgcagcccc ggtcccgccg 50

 cggcggggct cctcggcctg gctcctggag gagctgctgc ggcccgactg 100

 ccccgagccc gcgggcttgg acgcgacacg ggaggggccc gatcggaact 150

 tccgactgag cgagcaccgc caggccctgg ccgccgccaa gcaccgaggc 200

 cccgcggcga ccccggggag ccccgatccc ggccccggtc cgtggggcga 250

 agagcacttg gcggagaggg gccccagggg ctgggagagg ggcggcgatc 300

 gctgcgacgc gcccggtggg gacgcggcgc ggaggcccga cccagaggcc 350

 gaggcacccc ccgccgggag catcgaggcc gccccgagta gtgcggcgga 400

 gccggtgatc gtctccaggt cggatcccag agacgagaag ctggccctat 450

 acctggccga ggtggagaag caggacaagt atctgcggca gaggaataag 500

 taccgattcc acatcattcc agacggcaac tgcctctacc gagctgtcag 550

 caagacggtg tatggggacc agagcctgca ccgggagttg agggagcaga 600

 cggtgcacta catcgccgac catctcgacc acttcagccc cctgattgag 650

 ggcgacgtgg gggagtttat catcgctgct gcccaagacg gggcatgggc 700

 cgggtacccg gagttgctgg ccatggggca gatgctgaat gtgaatatcc 750

 atttaactac tggagggagg ctggagagtc ccacggtgtc taccatgatt 800

 cattatttgg gcccagagga ttccctgagg cctagtattt ggctcagttg 850

 gctcagtaac ggacactatg atgctgtatt tgatcactcc tatcctaacc 900

 cagagtacga caactggtgc aaacaaactc aagtgcaaag gaaacgcgac 950

 gaagaacttg ccaaatctat ggccatatcc ttgtctaaaa tgtatattga 1000

 acaaaatgca tgctcttgaa atgtctcaaa accttacacc ctgggaataa 1050

 ttgcatatat aacttgtgtt tggagaatca catgaacttt aatcagggta 1100

 atagcacttt caaacttgct agtagatttt actgtaggtg taatgcctta 1150

 atcatctttt tgaatgtttt ctcagagctg gaggttgctg ggcacctaaa 1200

 tgatgtttca tgatagcttt gggtgatttt actgctattt ataatttgct 1250

 gtataaagtg agcattactt aatttgcaag ctgatttctc acagtgtaaa 1300

 tttgttcatt cctggtagtc tattttctat aaaaatgtat ttttgcacaa 1350

 catttttaaa aactggtgta ccttcatcta tgacgtgttc cattttgaca 1400

 aacagctttc aggcgtaaat ccagagaagt gctttatatg aaatgtatta 1450

 ttttgaacag agtttgtgat ttggtagtta ttttatgttg ttgaaatttg 1500

 aatttcacaa ttcttagata attatttcaa atggatattg atgcattctt 1550

 gttaccagat gtttggccca ttccattttg atgaaacaga gctgttgttt 1600

 tggaagtcat tatttttcta gaaatggcga atcttttaaa gaaaattact 1650

 taatggaagg ttgtgggaag gtgttttttt gtgttttttt ttgggttttg 1700

 gttttgtttt tcctctttta agggatagta gcaggtctta cttgaatgaa 1750

 agtctgatat ttgctgatgg cagaatgatt attctgtacc ctggttgatg 1800

 tgtagagtag attgtctggt gctctcagtt gtttttattt acatttgtca 1850

 cgttgttgta agagaatgtt aacatggtat aaaactctgt gacaagataa 1900

 gcctcctgct ttatataact tcttgaatcc agctaagaga tttataaact 1950

 aatggcataa atgtctggag ccaaccttgg cagttatagc aggagaacac 2000

 tgtcttaata tttctttaca ttctttcaaa aggcaaaata ggattgccct 2050

 gtattgatgt agaaatgtct gtaaacagag cttgtatggt ttgctgggtc 2100

 aaacaatgtt tccaacttaa aatcaatctc attgccactt taactacttt 2150

 tagtcatatt tattaagtaa tgcagtttgt acttttttta ttttgtaaca 2200

 ttttgtgatt tttttgtaca aaactgtatt tgtacaatag agcaattccc 2250

 agctgatgga atgaatgaat aaaatgcaaa attatacttt tacaatgcct 2300

 ttttggatag agtggttttt aaattgtgat gtttgtagga aactttcttg 2350

 catgtatgca tgtacacaat tttttttttc cataaagatg ccccagcaat 2400

 agagaggttt cctaaattat cacatgaaga ggataggcta atcatgagta 2450

 atttcaaagg ataagtctga ataaaatata atttaaaagt ggagt 2495

<210> 4325
<211> 338
<212> PRT
<213> Homo sapien

<400> 4325
 Gly Arg Cys Leu Leu Leu Ala Pro Ala Pro Ala Ala Pro Val Pro
   1               5                  10                  15

 Pro Arg Arg Gly Ser Ser Ala Trp Leu Leu Glu Glu Leu Leu Arg
                  20                  25                  30

 Pro Asp Cys Pro Glu Pro Ala Gly Leu Asp Ala Thr Arg Glu Gly
                  35                  40                  45

 Pro Asp Arg Asn Phe Arg Leu Ser Glu His Arg Gln Ala Leu Ala
                  50                  55                  60

 Ala Ala Lys His Arg Gly Pro Ala Ala Thr Pro Gly Ser Pro Asp
                  65                  70                  75

 Pro Gly Pro Gly Pro Trp Gly Glu Glu His Leu Ala Glu Arg Gly
                  80                  85                  90

 Pro Arg Gly Trp Glu Arg Gly Gly Asp Arg Cys Asp Ala Pro Gly
                  95                 100                 105

 Gly Asp Ala Ala Arg Arg Pro Asp Pro Glu Ala Glu Ala Pro Pro
                 110                 115                 120

 Ala Gly Ser Ile Glu Ala Ala Pro Ser Ser Ala Ala Glu Pro Val
                 125                 130                 135

 Ile Val Ser Arg Ser Asp Pro Arg Asp Glu Lys Leu Ala Leu Tyr
                 140                 145                 150

 Leu Ala Glu Val Glu Lys Gln Asp Lys Tyr Leu Arg Gln Arg Asn
                 155                 160                 165

 Lys Tyr Arg Phe His Ile Ile Pro Asp Gly Asn Cys Leu Tyr Arg
                 170                 175                 180

 Ala Val Ser Lys Thr Val Tyr Gly Asp Gln Ser Leu His Arg Glu
                 185                 190                 195

 Leu Arg Glu Gln Thr Val His Tyr Ile Ala Asp His Leu Asp His
                 200                 205                 210

 Phe Ser Pro Leu Ile Glu Gly Asp Val Gly Glu Phe Ile Ile Ala
                 215                 220                 225

 Ala Ala Gln Asp Gly Ala Trp Ala Gly Tyr Pro Glu Leu Leu Ala
                 230                 235                 240

 Met Gly Gln Met Leu Asn Val Asn Ile His Leu Thr Thr Gly Gly
                 245                 250                 255

 Arg Leu Glu Ser Pro Thr Val Ser Thr Met Ile His Tyr Leu Gly
                 260                 265                 270

 Pro Glu Asp Ser Leu Arg Pro Ser Ile Trp Leu Ser Trp Leu Ser
                 275                 280                 285

 Asn Gly His Tyr Asp Ala Val Phe Asp His Ser Tyr Pro Asn Pro
                 290                 295                 300

 Glu Tyr Asp Asn Trp Cys Lys Gln Thr Gln Val Gln Arg Lys Arg
                 305                 310                 315

 Asp Glu Glu Leu Ala Lys Ser Met Ala Ile Ser Leu Ser Lys Met
                 320                 325                 330

 Tyr Ile Glu Gln Asn Ala Cys Ser
                 335

<210> 4326
<211> 768
<212> DNA
<213> Homo sapien

<400> 4326
 tgccatttca ttacctcttt ctccgcaccc gacatagatt ttttttcgtt 50

 aaaggtattt ttattgctag tacaagatgc aggatctagg caaataatat 100

 aacaattaaa tgtgcaaatc tcatgaaggt aaactacctt tctgttctgt 150

 aatattcacc caaatagtca aggctcagac ttgttaaact gtggagttac 200

 taaagaaggg gggattttcc aaattgtaga aacaagagta gtcagatttt 250

 cccatcccta ctagctttct aggttaaatt caatgatgtg aaaacaagca 300

 tagggtagag tccatatgat attcatacag gaagaatgtc cactggggaa 350

 gctctttcgg ccctcattca ccacgtcctt atcccctgta cacatcaagt 400

 cagaatgggc tagcccatca gggaagcagc ggtagaagaa atctgggcgt 450

 ggcctcccta cgatcagttt tattgtgttg gtaaagacgc cattcagagc 500

 cagggcaagg ctggcagctg caaagcaaag ccattagttg aaaggatctg 550

 tctaggagga aaggtatggt catggcctcg ttatgagagc agccgtgctg 600

 tttctgagat ggatagaatc caaccaggcc tgggcacaaa aataattagg 650

 gtcctcagtg atcactcttt tgtagccgag aacttttgta ctaggccaag 700

 acatttctga ggtacaataa cccagtgcat ttagccacag gctgcctgcc 750

 gtcgctacct taggaccg 768

<210> 4327
<211> 39
<212> PRT
<213> Homo sapien

<400> 4327
 Met Ile Phe Ile Gln Glu Glu Cys Pro Leu Gly Lys Leu Phe Arg
   1               5                  10                  15

 Pro Ser Phe Thr Thr Ser Leu Ser Pro Val His Ile Lys Ser Glu
                  20                  25                  30

 Trp Ala Ser Pro Ser Gly Lys Gln Arg
                  35

<210> 4328
<211> 5344
<212> DNA
<213> Homo sapien

<400> 4328
 cgcctgggcg cggcggaggg cggggagccg ggcaggtcgc gcctgcgggc 50

 ggcagccgac cgccgggagc tgttctgatt tccgacgcgc acgctagggg 100

 cccggagcag cccccggccc cggcgcgccg ccgacatggg caacgcaggg 150

 agcatggatt cgcagcagac cgatttcagg gcgcacaacg tgcctttgaa 200

 gctgccgatg ccagagccag gtgaactgga ggagcgattt gccatcgtgc 250

 tgaacgctat gaacctacct cctgacaaag ccaggttact gcggcagtat 300

 gataatgaga aaaaatggga actgatttgt gatcaggaac gattccaggt 350

 gaagaatcct ccccatacat acattcaaaa gctcaaaggc tatctggatc 400

 cagctgtaac caggaagaaa ttcagacggc gtgttcaaga atctacacaa 450

 gtgctaagag aactggaaat ttctttaaga actaaccaca ttggatgggt 500

 cagagaattt ctgaatgaag aaaacaaagg tcttgatgtt ctagtggaat 550

 atctctcatt tgcacagtac gcggtaactt ttgactttga aagtgtggag 600

 agtactgtgg agagctcggt ggacaaatca aagccctgga gtaggtccat 650

 cgaggacctg cacagaggga gcaacctgcc ctcacctgtg ggcaacagtg 700

 tctcccgctc tggaagacat tctgcactgc gatataatac attgccaagc 750

 agaagaactc tgaaaaattc aagattagtg agtaagaaag atgatgtgca 800

 tgtctgtatc atgtgtttac gtgccatcat gaattatcag tatggtttca 850

 acatggtcat gtctcatcca cacgctgtca atgagattgc actaagcctg 900

 aacaacaaga atcccagaac aaaagccctt gtcttagaac tgttggcagc 950

 cgtttgtctt gtcagaggcg ggcatgaaat cattttatca gcatttgata 1000

 actttaaaga ggtttgtgga gaaaaacagc gctttgagaa gttgatggaa 1050

 catttcagga atgaagacaa taacatagat tttatggtgg cttctatgca 1100

 gtttattaat attgtagtcc attcagtaga agatatgaat ttcagagttc 1150

 acctgcagta tgaatttacc aaattaggcc tggacgaata cttggacaag 1200

 ctgaaacaca ctgagagtga caagcttcaa gtccagatcc aggcttacct 1250

 ggacaatgtt tttgatgtag gagctctact ggaagatgct gaaactaaga 1300

 atgctgcctt ggagagggtg gaagaactgg aagaaaacat ttctcattta 1350

 tctgaaaaac tgcaagacac agagaatgaa gccatgtcca agattgtgga 1400

 actggaaaag caactcatgc agaggaacaa ggagctggat gtcgttcggg 1450

 aaatctacaa agatgcaaat actcaagttc acacattaag aaaaatggtc 1500

 aaagaaaaag aagaagcaat tcaaagacag tctaccctgg aaaaaaagat 1550

 tcatgagcta gagaaacaag ggaccattaa aattcagaag aaaggggatg 1600

 gggatatcgc catactgcca gttgtggctt ctggcacatt gtccatgggg 1650

 tcagaagtgg tagcaggtaa ctctgtggga cccacaatgg gggccgcttc 1700

 ctcaggaccc ttgccccctc ctccaccacc actgcctccc tcatcagaca 1750

 cacctgaaac agtgcaaaat ggtccagtaa caccacctat gccaccgccg 1800

 ccgccgccac cccctcctcc acctcctcct cccccaccgc cccctccccc 1850

 tcctcctctc ccaggccctg catctgagac tgtaccagct cctcccttag 1900

 cacctcccct tccctctgca cctccgctgc ctggaacatc ttcacccaca 1950

 gtggttttca actcaggatt agcagctgtg aaaattaaga agccaatcaa 2000

 gacgaagttc agaatgccag tgtttaactg ggttgctctg aagcccaatc 2050

 agatcaatgg cacagtcttc aatgaaattg atgatgagcg aattctggag 2100

 gatttaaatg tggatgaatt tgaggaaata ttcaagacaa aagcccaagg 2150

 acctgccatt gatctttctt caagcaaaca gaagatacca cagaagggat 2200

 caaacaaagt gacattacta gaagcaaaca gggccaaaaa tcttgccata 2250

 actttaagga aagctggaaa gactgctgat gaaatatgta aagctattca 2300

 tgtatttgac ttgaagacac tgcctgtgga ctttgtggaa tgcttgatgc 2350

 ggttcctacc aactgagaat gaagtgaaag tgcttcggct ctacgagcgg 2400

 gaaaggaagc ctctggaaaa cttgtcagat gaagatcggt tcatgatgca 2450

 gtttagtaaa atcgagaggc tcatgcagaa gatgaccatc atggccttca 2500

 ttgggaactt tgctgaaagc attcagatgc tgactcctca actacatgcg 2550

 attatagcag catctgtctc tataaagtcg tcccaaaaac tcaagaaaat 2600

 tctggagatc atcttagccc ttggaaacta catgaatagc agtaaaagag 2650

 gagcagttta tggatttaaa cttcagagtt tagatctgct cttagataca 2700

 aagtcaacag acagaaagca aacactgttg cactatatat ccaatgtggt 2750

 gaaagaaaaa tatcaccaag tgtccctgtt ttataatgag cttcattatg 2800

 tggaaaaagc tgctgcagtc tcccttgaga atgttttgct ggatgtcaag 2850

 gagctccaga ggggaatgga cttgaccaag agagagtaca ccatgcatga 2900

 ccataacacg ctgctgaagg agttcatcct caacaatgag gggaagctga 2950

 agaagctgca ggatgatgcc aagatcgcac aggatgcctt tgatgatgtt 3000

 gtgaagtatt ttggagaaaa ccccaagaca acaccaccct ctgtcttctt 3050

 tcctgtcttt gtccggtttg tgaaagcata taagcaagca gaagaggaaa 3100

 atgagctgag gaaaaagcag gaacaagctc tcatggaaaa actcctagag 3150

 caagaagctc tgatggagca gcaggatcca aagtctcctt ctcataaatc 3200

 aaagaggcag cagcaagagt taattgcaga attaagaaga cgacaagtta 3250

 aagataacag acatgtatat gagggaaaag atggtgccat tgaagatatt 3300

 atcacagatc ttagaaacca accatacaga cgagccgatg cggtgaggag 3350

 aagcgtcagg cggcgctttg atgatcagaa cttgcgttct gttaatggtg 3400

 ccgaaataac aatgtgaacc tgagactggc ctgcatgaat acagggtgtg 3450

 cgtgaatgaa actgcccaca tgaactttat gtgctacgat ttaactgcag 3500

 ccttgaacac acacaaaaat attcttaagg gctcagattt agcaaacacg 3550

 gaagaatttt aaaatgagct ctcctttcaa cccttgttaa caagtgccta 3600

 aaaatggaag tacctgttca gattaatcaa agcaatagga tttgatttga 3650

 ttaggtatct ttttacacca gtatgttatt tttaaccaaa atgtaaagtt 3700

 cttattaaac tcattacctg ccattgtgat tgtcccatca tggcccacct 3750

 ggtttcctga tgttgtaaat aacatcaatg catctgctgt gggtcctttg 3800

 ctgagatgtc ttcgaaggaa ttttgtttta gccatatcca tcaactttgt 3850

 attttacttg caatttggaa gaaggaaagt cacatgatga aactcctttt 3900

 gtctataacc aggccctggc aaagtgcaaa caggatgcaa ctgcagtggc 3950

 acaaaggtca ctcaatcctt tgtttccagt ttcacattct actacttctg 4000

 cgctagagaa cgatgctctg tgagaggcat tcactagtat gaatgtgggg 4050

 atatagtgta taagacttat ttgcagtact gtgttcttca gctagaggca 4100

 gctttttaaa taatgcaagt gtatttatta gcattaaaat taacatctca 4150

 gtaatcagca ttagcatttc tgaggaccat tattaattct gagaacagaa 4200

 attggtgcct tgcaaggaag tttactagct ctatcaacaa gcattcaagg 4250

 ttacatctgc tagcagagta gtgttaggaa cctggcctta ctctcctctg 4300

 acaatcgcaa ttttttctta ttttttataa attcaagaag atacacttgg 4350

 catcgtgtat cgaggctaag tttttcatgc atttcccaga ctacttatgg 4400

 agaattgcag tttaagttgc tgaaaagtat taacatggta ttaagcttaa 4450

 ataatacgta atgggactag atggcccact aagccactgt tattttcctt 4500

 cctctctggc agggcacttg atccattcca aagtcaaaaa ctggactgaa 4550

 gctaaatttg tacttttcat aatatacatt ctgcttctgg cttatcttct 4600

 tggtacatca atatattaat tgtaaagttt attgtatagt atttaaccgc 4650

 tgaagttcct attttatgtt gtgcttatgt gaaccccttg gtgaaggtcc 4700

 cttttccttg gatgtgtagt tatatgatct ttttaaatgt acagatattt 4750

 tgctataaaa tcggtgcagt tttttatggt ttttacactt ctctttaatt 4800

 cccacctaag cctctgggta atattgtaaa tattgtttta aaatgcatca 4850

 gcctatgcta tacaatctga atgttatttt aacttatagt tttttttaat 4900

 atatatattt aactataagg acagtttagg gaacaagtta cctaccacat 4950

 ttcactttag tgtacctatt tacagaaaga ttaaactgcc acctgcgggc 5000

 acattcccat aaatgtgtac tttactttaa aaagaacatg ccacgatttt 5050

 gtctttctgt ggactcaaca ttcacttcga ttaaaaatag caatttgacc 5100

 aagttggact tccactacaa agcagctgtt ttccaaagtt caatgctgac 5150

 atatatgtat attaaaataa ttgcctattt attaatctac aaatagacaa 5200

 cgttggcatg ttcttttctg tttgtctatt aatgggcctg cttcttagca 5250

 atattagaat gttttataaa agcaattcat gttacttttc tggtcttttc 5300

 atggcatatg agcaaataat aaactattta cactactatt ctgt 5344

<210> 4329
<211> 1112
<212> PRT
<213> Homo sapien

<400> 4329
 Phe Pro Thr Arg Thr Leu Gly Ala Arg Ser Ser Pro Arg Pro Arg
   1               5                  10                  15

 Arg Ala Ala Asp Met Gly Asn Ala Gly Ser Met Asp Ser Gln Gln
                  20                  25                  30

 Thr Asp Phe Arg Ala His Asn Val Pro Leu Lys Leu Pro Met Pro
                  35                  40                  45

 Glu Pro Gly Glu Leu Glu Glu Arg Phe Ala Ile Val Leu Asn Ala
                  50                  55                  60

 Met Asn Leu Pro Pro Asp Lys Ala Arg Leu Leu Arg Gln Tyr Asp
                  65                  70                  75

 Asn Glu Lys Lys Trp Glu Leu Ile Cys Asp Gln Glu Arg Phe Gln
                  80                  85                  90

 Val Lys Asn Pro Pro His Thr Tyr Ile Gln Lys Leu Lys Gly Tyr
                  95                 100                 105

 Leu Asp Pro Ala Val Thr Arg Lys Lys Phe Arg Arg Arg Val Gln
                 110                 115                 120

 Glu Ser Thr Gln Val Leu Arg Glu Leu Glu Ile Ser Leu Arg Thr
                 125                 130                 135

 Asn His Ile Gly Trp Val Arg Glu Phe Leu Asn Glu Glu Asn Lys
                 140                 145                 150

 Gly Leu Asp Val Leu Val Glu Tyr Leu Ser Phe Ala Gln Tyr Ala
                 155                 160                 165

 Val Thr Phe Asp Phe Glu Ser Val Glu Ser Thr Val Glu Ser Ser
                 170                 175                 180

 Val Asp Lys Ser Lys Pro Trp Ser Arg Ser Ile Glu Asp Leu His
                 185                 190                 195

 Arg Gly Ser Asn Leu Pro Ser Pro Val Gly Asn Ser Val Ser Arg
                 200                 205                 210

 Ser Gly Arg His Ser Ala Leu Arg Tyr Asn Thr Leu Pro Ser Arg
                 215                 220                 225

 Arg Thr Leu Lys Asn Ser Arg Leu Val Ser Lys Lys Asp Asp Val
                 230                 235                 240

 His Val Cys Ile Met Cys Leu Arg Ala Ile Met Asn Tyr Gln Tyr
                 245                 250                 255

 Gly Phe Asn Met Val Met Ser His Pro His Ala Val Asn Glu Ile
                 260                 265                 270

 Ala Leu Ser Leu Asn Asn Lys Asn Pro Arg Thr Lys Ala Leu Val
                 275                 280                 285

 Leu Glu Leu Leu Ala Ala Val Cys Leu Val Arg Gly Gly His Glu
                 290                 295                 300

 Ile Ile Leu Ser Ala Phe Asp Asn Phe Lys Glu Val Cys Gly Glu
                 305                 310                 315

 Lys Gln Arg Phe Glu Lys Leu Met Glu His Phe Arg Asn Glu Asp
                 320                 325                 330

 Asn Asn Ile Asp Phe Met Val Ala Ser Met Gln Phe Ile Asn Ile
                 335                 340                 345

 Val Val His Ser Val Glu Asp Met Asn Phe Arg Val His Leu Gln
                 350                 355                 360

 Tyr Glu Phe Thr Lys Leu Gly Leu Asp Glu Tyr Leu Asp Lys Leu
                 365                 370                 375

 Lys His Thr Glu Ser Asp Lys Leu Gln Val Gln Ile Gln Ala Tyr
                 380                 385                 390

 Leu Asp Asn Val Phe Asp Val Gly Ala Leu Leu Glu Asp Ala Glu
                 395                 400                 405

 Thr Lys Asn Ala Ala Leu Glu Arg Val Glu Glu Leu Glu Glu Asn
                 410                 415                 420

 Ile Ser His Leu Ser Glu Lys Leu Gln Asp Thr Glu Asn Glu Ala
                 425                 430                 435

 Met Ser Lys Ile Val Glu Leu Glu Lys Gln Leu Met Gln Arg Asn
                 440                 445                 450

 Lys Glu Leu Asp Val Val Arg Glu Ile Tyr Lys Asp Ala Asn Thr
                 455                 460                 465

 Gln Val His Thr Leu Arg Lys Met Val Lys Glu Lys Glu Glu Ala
                 470                 475                 480

 Ile Gln Arg Gln Ser Thr Leu Glu Lys Lys Ile His Glu Leu Glu
                 485                 490                 495

 Lys Gln Gly Thr Ile Lys Ile Gln Lys Lys Gly Asp Gly Asp Ile
                 500                 505                 510

 Ala Ile Leu Pro Val Val Ala Ser Gly Thr Leu Ser Met Gly Ser
                 515                 520                 525

 Glu Val Val Ala Gly Asn Ser Val Gly Pro Thr Met Gly Ala Ala
                 530                 535                 540

 Ser Ser Gly Pro Leu Pro Pro Pro Pro Pro Pro Leu Pro Pro Ser
                 545                 550                 555

 Ser Asp Thr Pro Glu Thr Val Gln Asn Gly Pro Val Thr Pro Pro
                 560                 565                 570

 Met Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro
                 575                 580                 585

 Pro Pro Pro Pro Pro Pro Pro Pro Leu Pro Gly Pro Ala Ser Glu
                 590                 595                 600

 Thr Val Pro Ala Pro Pro Leu Ala Pro Pro Leu Pro Ser Ala Pro
                 605                 610                 615

 Pro Leu Pro Gly Thr Ser Ser Pro Thr Val Val Phe Asn Ser Gly
                 620                 625                 630

 Leu Ala Ala Val Lys Ile Lys Lys Pro Ile Lys Thr Lys Phe Arg
                 635                 640                 645

 Met Pro Val Phe Asn Trp Val Ala Leu Lys Pro Asn Gln Ile Asn
                 650                 655                 660

 Gly Thr Val Phe Asn Glu Ile Asp Asp Glu Arg Ile Leu Glu Asp
                 665                 670                 675

 Leu Asn Val Asp Glu Phe Glu Glu Ile Phe Lys Thr Lys Ala Gln
                 680                 685                 690

 Gly Pro Ala Ile Asp Leu Ser Ser Ser Lys Gln Lys Ile Pro Gln
                 695                 700                 705

 Lys Gly Ser Asn Lys Val Thr Leu Leu Glu Ala Asn Arg Ala Lys
                 710                 715                 720

 Asn Leu Ala Ile Thr Leu Arg Lys Ala Gly Lys Thr Ala Asp Glu
                 725                 730                 735

 Ile Cys Lys Ala Ile His Val Phe Asp Leu Lys Thr Leu Pro Val
                 740                 745                 750

 Asp Phe Val Glu Cys Leu Met Arg Phe Leu Pro Thr Glu Asn Glu
                 755                 760                 765

 Val Lys Val Leu Arg Leu Tyr Glu Arg Glu Arg Lys Pro Leu Glu
                 770                 775                 780

 Asn Leu Ser Asp Glu Asp Arg Phe Met Met Gln Phe Ser Lys Ile
                 785                 790                 795

 Glu Arg Leu Met Gln Lys Met Thr Ile Met Ala Phe Ile Gly Asn
                 800                 805                 810

 Phe Ala Glu Ser Ile Gln Met Leu Thr Pro Gln Leu His Ala Ile
                 815                 820                 825

 Ile Ala Ala Ser Val Ser Ile Lys Ser Ser Gln Lys Leu Lys Lys
                 830                 835                 840

 Ile Leu Glu Ile Ile Leu Ala Leu Gly Asn Tyr Met Asn Ser Ser
                 845                 850                 855

 Lys Arg Gly Ala Val Tyr Gly Phe Lys Leu Gln Ser Leu Asp Leu
                 860                 865                 870

 Leu Leu Asp Thr Lys Ser Thr Asp Arg Lys Gln Thr Leu Leu His
                 875                 880                 885

 Tyr Ile Ser Asn Val Val Lys Glu Lys Tyr His Gln Val Ser Leu
                 890                 895                 900

 Phe Tyr Asn Glu Leu His Tyr Val Glu Lys Ala Ala Ala Val Ser
                 905                 910                 915

 Leu Glu Asn Val Leu Leu Asp Val Lys Glu Leu Gln Arg Gly Met
                 920                 925                 930

 Asp Leu Thr Lys Arg Glu Tyr Thr Met His Asp His Asn Thr Leu
                 935                 940                 945

 Leu Lys Glu Phe Ile Leu Asn Asn Glu Gly Lys Leu Lys Lys Leu
                 950                 955                 960

 Gln Asp Asp Ala Lys Ile Ala Gln Asp Ala Phe Asp Asp Val Val
                 965                 970                 975

 Lys Tyr Phe Gly Glu Asn Pro Lys Thr Thr Pro Pro Ser Val Phe
                 980                 985                 990

 Phe Pro Val Phe Val Arg Phe Val Lys Ala Tyr Lys Gln Ala Glu
                 995                1000                1005

 Glu Glu Asn Glu Leu Arg Lys Lys Gln Glu Gln Ala Leu Met Glu
                1010                1015                1020

 Lys Leu Leu Glu Gln Glu Ala Leu Met Glu Gln Gln Asp Pro Lys
                1025                1030                1035

 Ser Pro Ser His Lys Ser Lys Arg Gln Gln Gln Glu Leu Ile Ala
                1040                1045                1050

 Glu Leu Arg Arg Arg Gln Val Lys Asp Asn Arg His Val Tyr Glu
                1055                1060                1065

 Gly Lys Asp Gly Ala Ile Glu Asp Ile Ile Thr Asp Leu Arg Asn
                1070                1075                1080

 Gln Pro Tyr Arg Arg Ala Asp Ala Val Arg Arg Ser Val Arg Arg
                1085                1090                1095

 Arg Phe Asp Asp Gln Asn Leu Arg Ser Val Asn Gly Ala Glu Ile
                1100                1105                1110

 Thr Met


<210> 4330
<211> 780
<212> DNA
<213> Homo sapien

<400> 4330
 cgggagtggc gtgctgggcg tgcgcggctg cggtacggcg tgttggtccc 50

 agcggttcag ctgaggtagg gacgtgctgt aggccggaat gttaccggct 100

 gttggatctg tggatgagga agaggatcct gcggaggagg attgtcctga 150

 attggttccc attgagacga cgcaaagcga ggaggaggaa aagtctggcc 200

 tcggcgccaa gatcccagtc acaattatca ccgggtattt aggtgctggg 250

 aagacaacac ttctgaacta tattttgaca gagcaacata gtaaaagagt 300

 agcggtcatt ttaaatgaat ctggggaagg aagtgcgctg gagaaatcct 350

 tagctgtcag ccaaggtgga gagctctatg aagagtggct ggaacttaga 400

 aacggttgcc tctgctgttc agtgaagtga ggaatgtgtt tactgtgtac 450

 atggtttact agaaatgttt attgattata tttccagctt taattttctt 500

 gagtaattta actgaattta cacagtttgc ttcattgtat tttcaaacaa 550

 atagaaaata aacttattag gaagcatttt cttaaagtgt ttcttgctgt 600

 cttttctatc tgctctaatg ttttggtcct tttattgagt ttttattgct 650

 tttgatgtca gggcttattt aatctctagt gcatgaaagt ctcatatgta 700

 aaaaatgatt attctgaatt taatctgtca ttggtcatac ttctaagtgt 750

 tcaaccttat aaaaaaaata aatgactatc 780

<210> 4331
<211> 113
<212> PRT
<213> Homo sapien

<400> 4331
 Met Leu Pro Ala Val Gly Ser Val Asp Glu Glu Glu Asp Pro Ala
   1               5                  10                  15

 Glu Glu Asp Cys Pro Glu Leu Val Pro Ile Glu Thr Thr Gln Ser
                  20                  25                  30

 Glu Glu Glu Glu Lys Ser Gly Leu Gly Ala Lys Ile Pro Val Thr
                  35                  40                  45

 Ile Ile Thr Gly Tyr Leu Gly Ala Gly Lys Thr Thr Leu Leu Asn
                  50                  55                  60

 Tyr Ile Leu Thr Glu Gln His Ser Lys Arg Val Ala Val Ile Leu
                  65                  70                  75

 Asn Glu Ser Gly Glu Gly Ser Ala Leu Glu Lys Ser Leu Ala Val
                  80                  85                  90

 Ser Gln Gly Gly Glu Leu Tyr Glu Glu Trp Leu Glu Leu Arg Asn
                  95                 100                 105

 Gly Cys Leu Cys Cys Ser Val Lys
                 110

<210> 4332
<211> 2179
<212> DNA
<213> Homo sapien

<400> 4332
 ggggacagcc agggttagat gttctgagga ggcgggagca accgagagag 50

 cacgtgagca tctgtccttt ctacccgttc ctctttatct ttagtgttca 100

 gtagcagcgg ggatagcccg gggcccggtg tatggccacg gagttacagt 150

 gtccggactc catgccctgt cacaaccagc aagtaaactc tgcctcaacc 200

 ccaagtcccg agcagctgcg acctggcgat ctgatcctgg accacgcagg 250

 gggaaacaga gcctccaggg ccaaggtgat tctcctcacg gggtacgccc 300

 attctagcct gccggccgag ctggactctg gggcctgcgg cggctccagc 350

 ctcaactcag agggcaacag tggtagtggt gacagtagca gctatgacgc 400

 accagctggc aactccttcc tagaggactg cgaactctcc cggcagatcg 450

 gggcgcagct taagctgctg cctatgaatg atcagatacg ggagctacag 500

 accatcatcc gggacaagac agccagtaga ggtgacttca tgttttctgc 550

 ggatcgtttg atcagacttg ttgtggaaga gggattgaat cagctgccat 600

 ataaagaatg catggtgacc actccaacag ggtacaagta tgaaggagtg 650

 aaatttgaga agggaaattg tggggtcagc ataatgagaa gcggtgaggc 700

 aatggaacaa ggtttacgag actgctgtcg atccatacga attggaaaga 750

 tcctgattca gagtgatgag gagacacaaa gagccaaagt atattatgcc 800

 aaattccccc cagacattta ccggagaaaa gtccttctga tgtatccaat 850

 tctcagcact ggaaatactg taattgaagc tgtaaaggtt cttatagaac 900

 atggagttca acccagtgtt atcatcctac tcagtctgtt ctccactcct 950

 catggtgcca aatcaatcat tcaggagttt ccagagatca caattttaac 1000

 tactgaagtt catcctgttg cacctacaca ttttggacag aaatactttg 1050

 gaacagacta agttatttaa gtaaaataat tgtcttatgt aatattacaa 1100

 tcatgttttg attttctatt tgttttactg attcacttga gggtggcaga 1150

 gaaaaatgtg ttaaaatgct ttttagtttt ggaagtgggt atatttgagg 1200

 ttatatctca tttagttatt tgtttactgt tggcaccgaa ttcaacaatg 1250

 aagtatatgc aactcttaca aaacataaat tttaataata ttctaatgca 1300

 aattactgaa ccctcagtgc attaaaatta tttcctaatt tatgagcctc 1350

 ttagtttgga ggttgcttga agccacaaat aaaactcaaa tgagagtcag 1400

 ttctttgtcc cactgtagtt tgcattttgt ttagtttggt tttagctcta 1450

 ctaaggtttc acatatgtgg ctattgccac attcctctac tgttttcttt 1500

 ctgatactgg acatgctagt aacttggaga ggagaataaa agaatgtctc 1550

 ctggaatttt acattcccat taatgtcctc attcaattgg cagacctagg 1600

 atgtatggtt aactctcagg ccattatgtt tttcatggcc catttcccaa 1650

 actgcattgt tggtaggtgc cttgctaagc tgtaatgcag tgaagaagat 1700

 ggtggggcat ttttagtaat tggaactgta acattaatct acaagattga 1750

 accggggatg tctggatgct gacaagggag agccaagtac tgttaatgcc 1800

 atcaatcctc taggaaggaa ttggtggttt ttctgaagtg tgggggaaag 1850

 ggtggtttct tgctggattt catggccagt aagtaaattt aaatgcttca 1900

 tttttaattt ggatgtttct gctagagacc tttgatttgg aaattagtta 1950

 ttttgcatgt ttgtcaactg tatatgtatg aaaatagaaa aaaaacatgc 2000

 tttttgtaaa aacccctaag atttgtatat gttcatcttt aggcttctga 2050

 aagggagaga aatcatattg gaaatcagtg ttggtgttct gaaatctgct 2100

 tgtaaaactc tcatctcatt ttacattgat attaaaacat tttaacacta 2150

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2179

<210> 4333
<211> 309
<212> PRT
<213> Homo sapien

<400> 4333
 Met Ala Thr Glu Leu Gln Cys Pro Asp Ser Met Pro Cys His Asn
   1               5                  10                  15

 Gln Gln Val Asn Ser Ala Ser Thr Pro Ser Pro Glu Gln Leu Arg
                  20                  25                  30

 Pro Gly Asp Leu Ile Leu Asp His Ala Gly Gly Asn Arg Ala Ser
                  35                  40                  45

 Arg Ala Lys Val Ile Leu Leu Thr Gly Tyr Ala His Ser Ser Leu
                  50                  55                  60

 Pro Ala Glu Leu Asp Ser Gly Ala Cys Gly Gly Ser Ser Leu Asn
                  65                  70                  75

 Ser Glu Gly Asn Ser Gly Ser Gly Asp Ser Ser Ser Tyr Asp Ala
                  80                  85                  90

 Pro Ala Gly Asn Ser Phe Leu Glu Asp Cys Glu Leu Ser Arg Gln
                  95                 100                 105

 Ile Gly Ala Gln Leu Lys Leu Leu Pro Met Asn Asp Gln Ile Arg
                 110                 115                 120

 Glu Leu Gln Thr Ile Ile Arg Asp Lys Thr Ala Ser Arg Gly Asp
                 125                 130                 135

 Phe Met Phe Ser Ala Asp Arg Leu Ile Arg Leu Val Val Glu Glu
                 140                 145                 150

 Gly Leu Asn Gln Leu Pro Tyr Lys Glu Cys Met Val Thr Thr Pro
                 155                 160                 165

 Thr Gly Tyr Lys Tyr Glu Gly Val Lys Phe Glu Lys Gly Asn Cys
                 170                 175                 180

 Gly Val Ser Ile Met Arg Ser Gly Glu Ala Met Glu Gln Gly Leu
                 185                 190                 195

 Arg Asp Cys Cys Arg Ser Ile Arg Ile Gly Lys Ile Leu Ile Gln
                 200                 205                 210

 Ser Asp Glu Glu Thr Gln Arg Ala Lys Val Tyr Tyr Ala Lys Phe
                 215                 220                 225

 Pro Pro Asp Ile Tyr Arg Arg Lys Val Leu Leu Met Tyr Pro Ile
                 230                 235                 240

 Leu Ser Thr Gly Asn Thr Val Ile Glu Ala Val Lys Val Leu Ile
                 245                 250                 255

 Glu His Gly Val Gln Pro Ser Val Ile Ile Leu Leu Ser Leu Phe
                 260                 265                 270

 Ser Thr Pro His Gly Ala Lys Ser Ile Ile Gln Glu Phe Pro Glu
                 275                 280                 285

 Ile Thr Ile Leu Thr Thr Glu Val His Pro Val Ala Pro Thr His
                 290                 295                 300

 Phe Gly Gln Lys Tyr Phe Gly Thr Asp
                 305

<210> 4334
<211> 2864
<212> DNA
<213> Homo sapien

<400> 4334
 ctcgcttctc gttctactgc cccaggagcc cggcgggtcc gggactcccg 50

 tccgtgccgg tgcgggcgcc ggcatgtggc tgtgggagga ccagggcggc 100

 ctcctgggcc ctttctcctt cctgctgcta gtgctgctgc tggtgacgcg 150

 gagcccggtc aatgcctgcc tcctcaccgg cagcctcttc gttctactgc 200

 gcgtcttcag ctttgagccg gtgccctctt gcagggccct gcaggtgctc 250

 aagccccggg accgcatttc tgccatcgcc caccgtggcg gcagccacga 300

 cgcgcccgag aacacgctgg cggccattcg gcaggcagct aagaatggag 350

 caacaggcgt ggagttggac attgagttta cttctgacgg gattcctgtc 400

 ttaatgcacg ataacacagt agataggacg actgatggga ccgggcgatt 450

 gtgtgatttg acatttgaac aaattaggaa gctgaatcct gcagcaaacc 500

 acagactcag gaatgatttc cctgatgaaa agatccctac cctaagggaa 550

 gctgttgcag agtgcctaaa ccataacctc acaatcttct ttgatgtcaa 600

 aggccatgca cacaaggcta ctgaggctct aaagaaaatg tatatggaat 650

 ttcctcaact gtataataat agtgtggtct gttctttctt gccagaagtt 700

 atctacaaga tgagacaaac agatcgggat gtaataacag cattaactca 750

 cagaccttgg agcctaagcc atacaggaga tgggaaacca cgctatgata 800

 ctttctggaa acattttata tttgttatga tggacatttt gctcgattgg 850

 agcatgcata atatcttgtg gtacctgtgt ggaatttcag ctttcctcat 900

 gcaaaaggat tttgtatccc cggcctactt gaagaagtgg tcagctaaag 950

 gaatccaggt tgttggttgg actgttaata cctttgatga aaagagttac 1000

 tacgaatccc atcttggttc cagctatatc actgacagca tggtagaaga 1050

 ctgcgaacct cacttctaga ctttcacggt gggacgaaac gggttcagaa 1100

 actgccaggg gcctcataca gggatatcaa aatacccttt gtgctagccc 1150

 aagccctggg gaatcaggtg actcacacaa atgcaatagt tggtcactgc 1200

 atttttacct gaaccaaagc taaacccggt gttgccacca tgcaccatgg 1250

 catgccagag ttcaacactg ttgctcttga aaatctgggt ctgaaaaaac 1300

 gcacaagagc ccctgccctg ccctagctga ggcacacagg gagacccagt 1350

 gaggataagc acagattgaa ttgtacaatt tgcagatgca gatgtaaatg 1400

 catgggacat gcatgataac tcagagttga cattttaaaa cttgccacac 1450

 ttatttcaaa tatttgtact cagctatgtt aacatgtact gtagacatca 1500

 aacttgtggt catactaata aaattattaa aaggagcact aaaggaaaac 1550

 tgtgtgccaa gcatcatatc ctaaggcata cggaatttgg ggaagccacc 1600

 atgcaatcca gtgaggcttc agtgtacagc aaccaaaatg gtagggaggt 1650

 cttgaagcca atgagggatt tatagcatct tgaatagaga gctgcaaacc 1700

 accagggggc agagttgcac ttttccaggc tttttaggaa gctctgcaac 1750

 agatgtgatc tgatcatagg caattagaac tggaagaaac ttccaaaaat 1800

 atctaggttt gtcctcattt tacaaatgag gaaactaaac tctgtggaag 1850

 ggaaggggtt gcctcaaaag tcacagctta gctgggcaca gtggctcatg 1900

 ccgataatcc cagcaattca gaaagctgag gcaggaggat tacttgaggc 1950

 cagactgggc aatatagcaa gaccccatct ctaaaaaatt aggcatggtg 2000

 gtgcatgcct gtattcccag ctactcagga ggttgaggtg ggaggatcac 2050

 ttgagcccag aagttcaagg ttgcaatgag ccatgattac accacggcac 2100

 tacaaccttg gtggcacagt gagaacctga ctcttaaaaa aaaaaaaaaa 2150

 aaaaaaaaag ataactagaa cttctagaac atcttgttta cagttagcca 2200

 gaaactatac aagtggttta acatgcatta tcttactcaa tccatacaaa 2250

 agtcttatgg aggtgttagc actctttcta ctgatgaaga actgaggtac 2300

 ttcataaaac cacttaccca aggtgtcttg agtctggtac aactggcatt 2350

 caaatctagg tcagtctgcc cccagagcca ctacccttac ccctcactga 2400

 atctgccttt atattgttga gcccatgacc ccaaactgct ctttccaatt 2450

 tgaacttcca gggattttat tgtgaactta catagcaaca ttaaaatgaa 2500

 gttgaattgt ttttaatggc aacgccgtct gtctcctcta gcttaccgct 2550

 tctcaccttt caaccccatc tgtggccttt gtccaggccc acagcttagc 2600

 catggcttcc ctcctgcatc cctgccgtgg gttgctggcc tcacacttgc 2650

 agcagctgga cagtgatttt agaaggccac cagtccccat agctatgtga 2700

 caatgagaag caaacttttt tgtgacagat tgtattggca taggcatgat 2750

 agatggggat tggtacgttt tgaatcagca tttgcaaaaa aattgtcttg 2800

 aattttaaaa taaacaacaa agatttgttc attgagtgca aaaaaaaaaa 2850

 aaaaaaaaaa aaaa 2864

<210> 4335
<211> 355
<212> PRT
<213> Homo sapien

<400> 4335
 Ser Leu Leu Val Leu Leu Pro Gln Glu Pro Gly Gly Ser Gly Thr
   1               5                  10                  15

 Pro Val Arg Ala Gly Ala Gly Ala Gly Met Trp Leu Trp Glu Asp
                  20                  25                  30

 Gln Gly Gly Leu Leu Gly Pro Phe Ser Phe Leu Leu Leu Val Leu
                  35                  40                  45

 Leu Leu Val Thr Arg Ser Pro Val Asn Ala Cys Leu Leu Thr Gly
                  50                  55                  60

 Ser Leu Phe Val Leu Leu Arg Val Phe Ser Phe Glu Pro Val Pro
                  65                  70                  75

 Ser Cys Arg Ala Leu Gln Val Leu Lys Pro Arg Asp Arg Ile Ser
                  80                  85                  90

 Ala Ile Ala His Arg Gly Gly Ser His Asp Ala Pro Glu Asn Thr
                  95                 100                 105

 Leu Ala Ala Ile Arg Gln Ala Ala Lys Asn Gly Ala Thr Gly Val
                 110                 115                 120

 Glu Leu Asp Ile Glu Phe Thr Ser Asp Gly Ile Pro Val Leu Met
                 125                 130                 135

 His Asp Asn Thr Val Asp Arg Thr Thr Asp Gly Thr Gly Arg Leu
                 140                 145                 150

 Cys Asp Leu Thr Phe Glu Gln Ile Arg Lys Leu Asn Pro Ala Ala
                 155                 160                 165

 Asn His Arg Leu Arg Asn Asp Phe Pro Asp Glu Lys Ile Pro Thr
                 170                 175                 180

 Leu Arg Glu Ala Val Ala Glu Cys Leu Asn His Asn Leu Thr Ile
                 185                 190                 195

 Phe Phe Asp Val Lys Gly His Ala His Lys Ala Thr Glu Ala Leu
                 200                 205                 210

 Lys Lys Met Tyr Met Glu Phe Pro Gln Leu Tyr Asn Asn Ser Val
                 215                 220                 225

 Val Cys Ser Phe Leu Pro Glu Val Ile Tyr Lys Met Arg Gln Thr
                 230                 235                 240

 Asp Arg Asp Val Ile Thr Ala Leu Thr His Arg Pro Trp Ser Leu
                 245                 250                 255

 Ser His Thr Gly Asp Gly Lys Pro Arg Tyr Asp Thr Phe Trp Lys
                 260                 265                 270

 His Phe Ile Phe Val Met Met Asp Ile Leu Leu Asp Trp Ser Met
                 275                 280                 285

 His Asn Ile Leu Trp Tyr Leu Cys Gly Ile Ser Ala Phe Leu Met
                 290                 295                 300

 Gln Lys Asp Phe Val Ser Pro Ala Tyr Leu Lys Lys Trp Ser Ala
                 305                 310                 315

 Lys Gly Ile Gln Val Val Gly Trp Thr Val Asn Thr Phe Asp Glu
                 320                 325                 330

 Lys Ser Tyr Tyr Glu Ser His Leu Gly Ser Ser Tyr Ile Thr Asp
                 335                 340                 345

 Ser Met Val Glu Asp Cys Glu Pro His Phe
                 350                 355

<210> 4336
<211> 4699
<212> DNA
<213> Homo sapien

<400> 4336
 cagggctggc tttttttttt ttaataagat agctggtgcc caagattgtt 50

 ttccacctta aggataaaac ctgttaagaa agcctgaaca attacaaaaa 100

 aggaagaaaa ggagacttgg ccaactggtg tcaggagtct taacaaggtc 150

 atagtttgcc agcccctgcc ctaaacaaat aattcttgaa tgcctactgt 200

 ggtgtgtaag atatgagtaa ataccaggga tacacagaga acaaaagaga 250

 aaaactgcta ttcttgtgaa acttggaagt tggaggagac ttggaagatg 300

 cagaactgga tgactactca ttctcatgct atagccagtt ggaagtgaat 350

 ggatcgcagc actcactgac ctgtgctttt gaggacccag atgtcaacac 400

 caccaatctg gaatttgaaa tatgtggggc cctcgtggag gtaaagtgcc 450

 tgaatttcag gaaactacaa gagatatatt tcatcgagac aaagaaattc 500

 ttactgattg gaaagagcaa tatatgtgtg aaggttggag aaaagagtct 550

 aacctgcaaa aaaatagacc taaccactat agttaaacct gaggctcctt 600

 ttgacctgag tgtcatctat cgggaaggag ccaatgactt tgtggtgaca 650

 tttaatacat cacacttgca aaagaagtat gtaaaagttt taatgcacga 700

 tgtagcttac cgccaggaaa aggatgaaaa caaatggacg catgtgaatt 750

 tatccagcac aaagctgaca ctcctgcaga gaaagctcca accggcagca 800

 atgtatgaga ttaaagttcg atccatccct gatcactatt ttaaaggctt 850

 ctggagtgaa tggagtccaa gttattactt cagaactcca gagatcaata 900

 atagctcagg ggagatggat cctatcttac taaccatcag cattttgagt 950

 tttttctctg tcgctctgtt ggtcatcttg gcctgtgtgt tatggaaaaa 1000

 aaggattaag cctatcgtat ggcccagtct ccccgatcat aagaagactc 1050

 tggaacatct ttgtaagaaa ccaagaaaaa atttaaatgt gagtttcaat 1100

 cctgaaagtt tcctggactg ccagattcat agggtggatg acattcaagc 1150

 tagagatgaa gtggaaggtt ttctgcaaga tacgtttcct cagcaactag 1200

 aagaatctga gaagcagagg cttggagggg atgtgcagag ccccaactgc 1250

 ccatctgagg atgtagtcat cactccagaa agctttggaa gagattcatc 1300

 cctcacatgc ctggctggga atgtcagtgc atgtgacgcc cctattctct 1350

 cctcttccag gtccctagac tgcagggaga gtggcaagaa tgggcctcat 1400

 gtgtaccagg acctcctgct tagccttggg actacaaaca gcacgctgcc 1450

 ccctccattt tctctccaat ctggaatcct gacattgaac ccagttgctc 1500

 agggtcagcc cattcttact tccctgggat caaatcaaga agaagcatat 1550

 gtcaccatgt ccagcttcta ccaaaaccag tgaagtgtaa gaaacccaga 1600

 ctgaacttac cgtgagcgac aaagatgatt taaaagggaa gtctagagtt 1650

 cctagtctcc ctcacagcac agagaagaca aaattagcaa aaccccacta 1700

 cacagtctgc aagattctga aacattgctt tgaccactct tcctgagttc 1750

 agtggcactc aacatgagtc aagagcatcc tgcttctacc atgtggattt 1800

 ggtcacaagg tttaaggtga cccaatgatt cagctattta aaaaaaaaag 1850

 aggaaagaat gaaagagtaa aggaaatgat tgaggagtga ggaaggcagg 1900

 aagagagcat gagaggaaag acagacagga aaataaaaaa tgatagttgc 1950

 cattattagg atttaatata tatccagtgc tttgcaagtg ctctgcgcac 2000

 cttgtctcac tccatcctga caataatcct gggaggtgtg tgcaattact 2050

 acgactactc tcttttttat agatcattaa attcagaact aaggagttaa 2100

 gtaacttgtc caagttgttc acacagtgaa gggaggggcc aagatatgat 2150

 ggctgggagt ctaattgcag ttccctgagc catgtgcctt tctcttcact 2200

 gaggactgcc ccattcttga gtgccaaacg tcactagtaa cagggtgtgc 2250

 ctagataatt tatgatccaa actgagtcag tttggaaagt gaaagggaaa 2300

 cttacatata atccctccgg gacaatgagc aaaaactagg actgtcccca 2350

 gacaaatgtg aacatacata tcatcactta aattaaaatg gctatgagaa 2400

 agaaagaggg ggagaaacag tcttgcgggt gtgaagtccc atgaccagcc 2450

 atgtcaaaag aaggtaaaga agtcaagaaa aagccatgaa gcccatttga 2500

 tttcattttt ctgaaaatag gctcaagagg gaataaatta gaaactcaca 2550

 atttctcttg tttgttacca agacagtgat tctcttgctg ctaccaccca 2600

 actgcatccg tccatgatct cagaggaaac tgtcgctgac cctggacatg 2650

 ggtacgtttg acgagtgaga ggaggcatga cccctcccat gtgtatagac 2700

 actaccccaa cctaaattca tccctaaatt gtcccaagtt ctccagcaat 2750

 agaggctgcc acaaacttca gggagaaaga gttacaagta catgcaatga 2800

 gtgaactgac tgtggctaca ttcttgaaga tatacggaag agacgtatta 2850

 ttaatgcttg acatatatca tcttgccttt cttggtctag actgacttct 2900

 aatgactaac tcaaagtcaa ggcaactgag taatgtcagc tcagcaaagt 2950

 gcagcaaacc catctcccac aggcctccaa accctggctg ttcacagaac 3000

 cacaaagggc agatgctgca cagaaaacta gagaaggggt cataggttca 3050

 tggttttgtt tgagatttgt tgctactgtt tttctgtttt gaattttctt 3100

 ctttgttctg tttttacttt atttaggggg actaggtgtt tctgatattt 3150

 tagttttctt gtttgttttg ttttgtgttg tctgtgaatg gggttttaac 3200

 tgtggatgaa tggaccttat ctgttggctt aaaggactgg taaaatcaga 3250

 ccatcttatt cttcaggtga atgttttact ttccaaagtg ctctcctctg 3300

 caccagcagt aataaataca atgccataat cccttaggtt tgcctagtgc 3350

 ttttgcaatt ttcaaagcac ttccataagc attccttcca cctccttgat 3400

 aggcatttat ggaaagcctg ctacatgtca atcatactgt taggcacagg 3450

 ggacctaaag acacataaaa ggatggcatt ctgcctcata aattgcaaaa 3500

 cctaatgaaa gtgactgctt ggtaaacaaa ttattattat attataaaat 3550

 gctataaaag agccatattg aaagtgccct gttggagaca gggcaaatgc 3600

 cacaaaaatg atgtaaattt acatggagga aaagtagaat ctgcctggtt 3650

 tgtaggcagc agaagacatt tttcatcagt gggcaggtgt tctttacctt 3700

 ttgtagaaat gggagtcaag tctcaaatag gaggctccac aaaatctcat 3750

 gccaggtctc tgatacctta ttcacagaag ttctttgaag tatttattgt 3800

 tattttcttt gacttatggg aaaactggga cacaggaaga caggtaaatt 3850

 acccaacctc acacgttaag tcagaactgg gagccataat tttgtatccc 3900

 tggtataaat agacaatctc ttgaagaaat gaagagatga ccatagaaaa 3950

 acatcgagat atctccagct ctaaaatcct ttgtttcaat gttgtttggc 4000

 atatgttatc tttggaattt agtgtctgag cctctgtctg ttactgtagt 4050

 atttaaaatg catgtattat aatcatataa tcataactgc tgttaattct 4100

 tgattatata cctagggaca atgtgtaatg taagattact aattggttct 4150

 gcccaatctc ctttcagatt ttattaggaa aaaaaaataa acctcctgat 4200

 cggagacaat gtattaatca gaagtgtaaa ctgccagttc tatatagcat 4250

 gaaatgaaaa gacagctaat ttggtccaac aaacatgact gggtctaggg 4300

 cacccaggct gattcagctg atttcctacc agcctttgcc tcttccttca 4350

 atgtggtttc catgggaatt tgcttcagaa aagccaagta tgggctgttc 4400

 agaggtgcac acctgcattt tcttagctct tctagagggg ctaagagact 4450

 tggtacgggc caggaagaat atgtggcaga gctcctggaa atgatgcaga 4500

 ttaggtggca tttttgtcag ctctgtggtt tattgttggg actattcttt 4550

 aaaatatcca ttgttcacta cagtgaagat ctctgattta accgtgtact 4600

 atccacatgc attacaaaca tttcgcagag ctgcttagta tataagcgta 4650

 caatgtatgt aataaccatc tcatatttaa ttaaatggta tagaagaac 4699

<210> 4337
<211> 296
<212> PRT
<213> Homo sapien

<400> 4337
 Met His Asp Val Ala Tyr Arg Gln Glu Lys Asp Glu Asn Lys Trp
   1               5                  10                  15

 Thr His Val Asn Leu Ser Ser Thr Lys Leu Thr Leu Leu Gln Arg
                  20                  25                  30

 Lys Leu Gln Pro Ala Ala Met Tyr Glu Ile Lys Val Arg Ser Ile
                  35                  40                  45

 Pro Asp His Tyr Phe Lys Gly Phe Trp Ser Glu Trp Ser Pro Ser
                  50                  55                  60

 Tyr Tyr Phe Arg Thr Pro Glu Ile Asn Asn Ser Ser Gly Glu Met
                  65                  70                  75

 Asp Pro Ile Leu Leu Thr Ile Ser Ile Leu Ser Phe Phe Ser Val
                  80                  85                  90

 Ala Leu Leu Val Ile Leu Ala Cys Val Leu Trp Lys Lys Arg Ile
                  95                 100                 105

 Lys Pro Ile Val Trp Pro Ser Leu Pro Asp His Lys Lys Thr Leu
                 110                 115                 120

 Glu His Leu Cys Lys Lys Pro Arg Lys Asn Leu Asn Val Ser Phe
                 125                 130                 135

 Asn Pro Glu Ser Phe Leu Asp Cys Gln Ile His Arg Val Asp Asp
                 140                 145                 150

 Ile Gln Ala Arg Asp Glu Val Glu Gly Phe Leu Gln Asp Thr Phe
                 155                 160                 165

 Pro Gln Gln Leu Glu Glu Ser Glu Lys Gln Arg Leu Gly Gly Asp
                 170                 175                 180

 Val Gln Ser Pro Asn Cys Pro Ser Glu Asp Val Val Ile Thr Pro
                 185                 190                 195

 Glu Ser Phe Gly Arg Asp Ser Ser Leu Thr Cys Leu Ala Gly Asn
                 200                 205                 210

 Val Ser Ala Cys Asp Ala Pro Ile Leu Ser Ser Ser Arg Ser Leu
                 215                 220                 225

 Asp Cys Arg Glu Ser Gly Lys Asn Gly Pro His Val Tyr Gln Asp
                 230                 235                 240

 Leu Leu Leu Ser Leu Gly Thr Thr Asn Ser Thr Leu Pro Pro Pro
                 245                 250                 255

 Phe Ser Leu Gln Ser Gly Ile Leu Thr Leu Asn Pro Val Ala Gln
                 260                 265                 270

 Gly Gln Pro Ile Leu Thr Ser Leu Gly Ser Asn Gln Glu Glu Ala
                 275                 280                 285

 Tyr Val Thr Met Ser Ser Phe Tyr Gln Asn Gln
                 290                 295

<210> 4338
<211> 3699
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 116-133
<223> Unknown base

<400> 4338
 cggcgcgtgg gtgagccaat gtgcctggcc attcctgtga ttttttagaa 50

 tttttcactt ttcatataaa gttgcatttt atcatgagga aaatgttttg 100

 gctgaaaaac atatgnnnnn nnnnnnnnnn nnntcagttt tcactatttt 150

 tccagcttgc ctagggaaac gtcctcccct gagcaaagtg ggatgtgcat 200

 ggctcttttt tgtgattaag caggcatcaa atgggcagtt ttcattttca 250

 ctgacacaga aacatgtggc tgaagcagga ataaaatcct gcctactgac 300

 ttctgtctcc attcttgctc caggtaaaat cagagaacct ccccttcttg 350

 gccctttaat tcccccaggc agaggcggct ccagctcctg ttaagggccc 400

 cagttttact catgctacct gaccttagtt ttagtacttt caaatgtgat 450

 ttgggtaaaa actattttgc aggcaaaagt gttaattttt tataaatatg 500

 tataataaaa aagctataaa agtttttcct tttcttgtat ttttcaaata 550

 ctccccaaga cacaatcctt gaaggtgaac taggtggcac ttgattatgc 600

 taattgtggg agctactgaa ctatactgat taaattaaat gcttgcaggt 650

 tcctgggtaa ttttcctttg tgaataacct ggcgctacct gaatttttct 700

 ctaacaaaca tctccaatga gggtaaacaa tgatcttgat tctaatttat 750

 atgaggttaa aaaccttcag atttcgtatt ttgaattgtt ctccctagtt 800

 tcctcagtgg ttaccccctt ttagtcagta accatctctg ttcagaattc 850

 agtctttggc ttttgaagaa atgggcacag agccaaagga cccatttcac 900

 agttcccttg gaatatattt cccattgttg gactgaggca aacaaaacca 950

 actgtgcaaa tcacaagcaa aagagacttc tgtccgtagt tgcgagtgcc 1000

 atcagtgtga gcttaccagc tacaaaaatc tgtcatggac tggggaacag 1050

 tatgattcct tattgaaact ttcatcctca tcggctggct tgtcagcgtt 1100

 ctgaagttaa tatccatgct gcctgaaaca aatgttatgt ttaactagca 1150

 cttacttaac ttttaaaatt gcttaattct cctttcagat gcatgcacta 1200

 agtcttctct gagcctgcag caatatttta gagggacctc ttctaagtca 1250

 gagccttgac attctactcc aaaaggaagt ccaaattaga gcccataggc 1300

 tttttcttaa aagctgttaa ggagtagtaa gaaagttacc actctaagga 1350

 aaacatgaaa ctatctgaaa gtcttctggt tcctaactgg atacagatta 1400

 gattatttta aatgagaaaa aagtgcaccg tagttacccg atcaagattg 1450

 gactgcctgt gtccctggca tgaattaaag aacctccata gttgcttgtt 1500

 cccttctgaa ggtgtttcct atggcccacg agaattataa agcaatcact 1550

 ttttaagtct atcagtcaac cttaatagct ctcaagagtt tcgattatca 1600

 agctttaaag tgataacata tcaagatgac tattaaaaaa taaacatctc 1650

 tgaaagtgtc ctttcctcca taaggcttta aacaatttgc aaattcttaa 1700

 ttgggagtat gtcccaatca ttctattaaa ctatttacag ctctacctac 1750

 ttctagattc agcaaacaga gctactagtt agagtatttt gagagccaaa 1800

 atagtaagag acttctgtaa tggttgagat ttctgcactg accttaatta 1850

 gggtaccgcc atagggctac caaagttttt agtgagggct ggggaggtgg 1900

 agcataagta acattttttt tctgcagaag gtgatggctt tgtagaacac 1950

 tataaaattt ttcaggaaaa catacagcaa attttcttat ccagtgggaa 2000

 cagcctattt gacaaggaat gatatacaag tttgattcac ctttgagcac 2050

 tcttatagag tttacagaag aggcgtaact ggttacaaaa caaaagttac 2100

 gccttcacta tccagttctt aaagtttatc cacatcctac aaatcttatg 2150

 ttcatgtagg tcaggttaaa gtaagctcca aacttatggc cttcagaagc 2200

 atctcctgtt taacacacct gaaattactc taacttaata catttgtatt 2250

 ctctaagaaa taatgctgac tgctgtcacc acagcatcac tgatctctca 2300

 gtggctgtta aaatataaac aagtggaaaa aaagtataca agttgatagc 2350

 agctgttcat gtattcttgt tttgctaata cctgtgtaga gaaagacagt 2400

 ttcacatgca gatcaccata catttttgct taaaggttac actgggtaaa 2450

 ctgtttgttt atcacattac atctgggtga gattttgcat gtgaccaaga 2500

 ggaagaaatc attcagtccc ggaaatagca actgctatgt aaaaccacat 2550

 ccttgactag tacttcatct ttccacagtc atccatctgc taatcaggtg 2600

 aaatatcagc tcagcagaac aaagcaagtt atacacaaat ttcccccaca 2650

 ttcacactga tgccgtactt agtaattctg gttctaccat tcccttttgc 2700

 actttttgca agtcaaattc atgtggaaaa atgttctgtt tgtagaactc 2750

 atagtattca cttatagtgc tcatgtcagg aatggcaagt gagtaagagc 2800

 ccctgataat ctgcttttgt tagaacgtaa tgcaaagata ataaaacatg 2850

 tccacttctt ttctagttct aatcagtttt tagacatcaa gatttattta 2900

 ctttgcatga gatttgtttc ctattatttg aatatgtgct atacacttga 2950

 attagaaaaa cctgcttgaa tgtattgtca gttattaaag cacatgtgac 3000

 taagtttgca tttgtcagta ttgttctact gtttgtactg aaagtctcat 3050

 tttaaaattg ctacttaaca ctgtactata ccttgtaatt ttttagattc 3100

 tccacttgta ttctttaaat gtttccagat gcctttagtt ttagctgctg 3150

 taaaatagct actttgcgtt atttgatata gaattgtttt ttaaaaactc 3200

 catttattta tacagagaca tttataatat tttacaaaca ttcttatatt 3250

 ctgaataaat atttctaatt ccacagtgta ccttaactgt gttatttaaa 3300

 gggtaaggct atccttctgt agaactgtga tatacatgca ggcaaatatc 3350

 aaatccatga tgcttacatg aaatcaagag ccctagtcaa agcaggggtc 3400

 tagaagtaag actattatta gatcaaaatg gccaaagaac cctcatttat 3450

 agcccatttt tagttggctt tttaaaattt ggcataaata ggaagttatc 3500

 tattgaagag agtcttttcc cctcttaaag aaagatcatt aaaatggaat 3550

 gtaatcaagg actggaaatg caaggaagtc atataggaca acaagatggc 3600

 aagcagcttt gcaacacatc tgttagagaa agattacaat gttctcaagt 3650

 tttcactatg gaagcaaagt aactttgaca gtaagtataa caccttagt 3699

<210> 4339
<211> 34
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 116-133
<223> Unknown amino acid

<400> 4339
 Met Ala Ser Ser Phe Ala Thr His Leu Leu Glu Lys Asp Tyr Asn
   1               5                  10                  15

 Val Leu Lys Phe Ser Leu Trp Lys Gln Ser Asn Phe Asp Ser Lys
                  20                  25                  30

 Tyr Asn Thr Leu


<210> 4340
<211> 1088
<212> DNA
<213> Homo sapien

<400> 4340
 tgagactgtg tctcaaaaac aaaaaagaaa aagagaggaa agaaagaaaa 50

 cattatatgc ctgggattac aagcatgagc ccagcgcctg gctgtatctt 100

 tcattttacc caagtcactt tacccaagta agtaattagg ggaaagcctg 150

 agtcttgtac cacctgttca tttggggaac tgtgggaaac ggagccaacg 200

 gacctaagtg ccctttgaca gtgagtttca taccatttca gtagtgtatt 250

 tctttcttaa tctgaataaa ccagaatgat actctcagca cagaagaata 300

 aagggagcga gtcattaacg ttttcttttt aaacctttat gatgacttcc 350

 ttatgaatta ctgaacgaac actggaatgg gactcaggta tcctgaggac 400

 atctctcaac tctggcctta gttccccctc tgtaaaatta gggtgccaac 450

 taaatgatct acaaggtccc ttccagcgcc gccattctgt aattacatca 500

 tgtgtaactg tattaaacat acacaagtga ctgccaggca tgggaatgta 550

 acttccgagt aaatgctttg gtttgttcag aatacactat gaacttcttt 600

 ccaaagacgg gttgtggtaa atagtggata ttttgattat aagaaataga 650

 gtttccttga agctttagct ggagatacag caatagtgtg gtgttcctac 700

 aaatatcaca gtgtattcaa acatattttt ctatcaaaaa tcatttttgt 750

 aaaagctgtg tgtttttatc caacttgtga taataaatgt tctttatttt 800

 agaataaaaa ctggcctttt tgtatgtatt gaatacagtt aatagaattt 850

 ataattttaa ttaacaattt gctctttcat gtgtgaatat gtgatagtct 900

 agtcctttca aaagattgag acggactggc tttcattgtt tgaaggctgg 950

 tgagagaagg ggttacctgc tgcacaccag tggggagtga catactccta 1000

 acacatgcca gaaacaaaaa gtttggtcat aaaacagttc taataagaaa 1050

 tctgcctggc ctgctcacac ctgtaacccc agcacttt 1088

<210> 4341
<211> 45
<212> PRT
<213> Homo sapien

<400> 4341
 Glu Thr Val Ser Gln Lys Gln Lys Arg Lys Arg Glu Glu Arg Lys
   1               5                  10                  15

 Lys Thr Leu Tyr Ala Trp Asp Tyr Lys His Glu Pro Ser Ala Trp
                  20                  25                  30

 Leu Tyr Leu Ser Phe Tyr Pro Ser His Phe Thr Gln Val Ser Asn
                  35                  40                  45

<210> 4342
<211> 1098
<212> DNA
<213> Homo sapien

<400> 4342
 ctcctgctca gcatggctgc tttagggact gttctcttca caggtgtccg 50

 gaggctgcac tgcagcgtag ccgcttgggc gggcggccag tggcgactac 100

 agcagggact ggctgccaac ccctccggct acgggcccct taccgagctc 150

 ccagactggt catatgcgga tggccgccct gctcccccaa tgaaaggcca 200

 gcttcgaaga aaagctgaaa gggagacgtt tgcaagacga gttgtactgc 250

 tgtcacagga aatggacgct ggattacaag catggcagct caggcagcag 300

 aagttgcagg aagaacaaag gaagcaggaa aatgctctta aacccaaagg 350

 ggcttcactg aagagcccac ttccaagtca ataaaaagca actcctgcct 400

 cccttcctca ccctgtctct ggatttcttt tctatcacct agatgcttca 450

 tccagccaga agatagcctt cacgttcccc atctgtcttc agagaaaaag 500

 agctgggaca ccaagaacaa gctgttagat cactgcctgg gaggcttggc 550

 ttagtactct catctctggt tccattccag ttcagctaag tcttgcttta 600

 aaatttttac ctcctagctg ggtgcggtgg ctcacgcctg taatcccagc 650

 actttgggag gctgaggcgg gcagatcaca agatcaggag ttcgagacca 700

 gcctggccaa cccagcctgg tcaacatggt gaaaccctgt ccctactaaa 750

 gatacaaaca attagccggg cgtggtgggg tgcgcttgta atcccagcta 800

 ctcaggaggc tgaggcagga gaatcgctta aactcgggag gtagaggttg 850

 cagtgagcca aggtcacacc attgcactcc aacctgggcg acagggcgag 900

 actccgtctc aaaaaaaaaa aaaaatttac ctcctttgca ggccatagga 950

 ctagcccaac tatgagaaat agctgttctg tgaacgtgaa aaggggacag 1000

 cagttttccc agttttggcc aggcagtcaa gcctttaaca gctcatgcac 1050

 agtttaggcc atgtacagct ggcatctaat aaatgttttc atgaaaaa 1098

<210> 4343
<211> 9162
<212> DNA
<213> Homo sapien

<400> 4343
 tcgtatattg tgtggaagaa ttcggctcga gtggcagcgg cggtagcagt 50

 ggcaacggca gcaagaggac cggccgcccc atagaccccc ccgcgcacca 100

 cccccgccgc ttcctctgct tgggtgcccc cccggtctga cttccctttt 150

 ctcccacctt tcccggcacc gcgggaaaag cagcgcaggg cagagcaggc 200

 agggagggcg gccggagccc ggacacggga gcctcccagt cagttcaaga 250

 cccgacatga gggaaaaggg acgtaggaag aagggcagga cctgggcgga 300

 ggccgccaag acggtcttag aaaaataccc caatacaccc atgagtcata 350

 aagaaattct tcaagttatc cagagagaag gactaaaaga aatcagaagt 400

 gggacttctc ctcttgcatg cctgaatgca atgcttcaca caaactccag 450

 aggtgaagag ggcatcttct ataaggttcc aggtagaatg ggagtatata 500

 ctttgaagaa agatgtgccg gatggggtga aagagctgtc agaaggttca 550

 gaagaaagca gtgatggtca gtcagattcc cagagttctg agaacagcag 600

 cagcagcagt gatggtggca gcaacaagga gggaaaaaag agcaggtgga 650

 aaaggaaagt atcgtcgtcc tccccgcagt caggctgccc atcacccacc 700

 attccagcag gtaaagtcat ttctccatca cagaagcaca gccaagaagg 750

 cactaaagca ggcgctaaag cagcaacagc agaagaagca gcagcagcaa 800

 tgcaggccaa gcatatccat ctcctccaac cagcatctct cactaaagac 850

 tgtcaaagca gccagtgact ctgtacctgc caaacctgca acatgggaag 900

 gaaagcaatc tgatggacag acaggcagcc ctcaaaactc aaactccagc 950

 ttttcttcct cagttaaagt ggaaaatact ttactaggct tggggaagaa 1000

 gtcattccag agatctgaga gactccatac cagacaaatg aaaagaacta 1050

 aatgtgctga cattgacgtt gagacaccgg actccattct ggttaataca 1100

 aatctgcgag cactgatcaa caagcacaca ttttcagtcc ttcctggaga 1150

 ttgccagcaa cgactgcttt tactactccc agaggtagat cgacaggttg 1200

 gtccagatgg tttaatgaag ttaaatggct cagcccttaa caatgaattc 1250

 ttcacttcag cagcccaagg ctggaaggaa agactctcag aaggtgagtt 1300

 tacacctgag atgcaggtga gaattcgaca agagattgag aaggagaaaa 1350

 aagtggagcc atggaaagaa caattctttg aaagctacta tgggcagagt 1400

 tctggcctga gccttgaaga ttctaagaaa ttgacagctt ctcccagtga 1450

 tcccaaagta aagaaaaccc cagctgaaca accaaaatcc atgcctgtgt 1500

 cagaggcctc tcttatcaga atagttccag tagtctccca gtcagagtgt 1550

 aaagaagaag cattgcaaat gtcatcacca ggcagaaaag aagagtgtga 1600

 aagccaaggt gaagtgcagc cgaacttctc cacatcttca gagcccctgc 1650

 tttcctcagc tctcaataca catgagctta gcagcattct tcccatcaag 1700

 tgcccaaagg atgaggatct cttggagcag aagccagtca cctctgctga 1750

 acaggaatct gagaagaacc atctcaccac agcttctaat tataacaaaa 1800

 gtgaaagcca agaatcttta gttacatcgc caagcaaacc caagagtcct 1850

 ggggttgaaa aaccaatagt gaagcccaca gcaggagcgg gtccacagga 1900

 gactaatatg aaagaacctc tagcaactct tgttgatcag agcccagaaa 1950

 gcctcaagag gaagtcttcc ctcacccaag aagaggcccc tgtgagctgg 2000

 gagaagaggc cacgtgtcac tgagaatcgc cagcaccagc agccatttca 2050

 ggtctcacca cagccctttc tcaatagagg ggacagaatc caggtgcgaa 2100

 aagtaccacc tctcaagatc ccggtctcca gaatctcccc catgccgttt 2150

 catccatcgc aggtctctcc cagggctcgt tttccagtct ccatcactag 2200

 tcctaacaga acaggagcca gaactcttgc agacatcaaa gcaaaagccc 2250

 aactggtcaa agcacagagg gcagcagctg ccgctgccgg ccgcagctgc 2300

 tgcagccgcc tcagttggag ggaccattcc aggacctggc ccagggggtg 2350

 gacaaggtcc aggagagggt ggtgaagggc agactgctag aggaggcagt 2400

 ccaggctcag acagagtcag tgaaactgga aagggcccca cactggaact 2450

 ggcaggaact ggaagcaggg gaggtacgag agagctttta ccctgtggtc 2500

 cagagactca gccccagtct gagaccaaga ccaccccaag ccaggcacag 2550

 cctcatagtg tctctggagc acaactacag caaacccccc cagtgcctcc 2600

 aacacctgcc gtcagtggag catgcacaag tgtcccatca ccagcccaca 2650

 tagagaaatt ggataatgaa aaactgaacc ccaccagagc aacagccaca 2700

 gtggcctctg tcagccatcc acaagggccc agtagttgca gacaggagaa 2750

 agcaccttct ccaacaggtc ctgctctaat ctcaggtgcc tcacctgttc 2800

 attgtgcagc tgatggcaca gttgagctca aagcaggtcc tagtaagaat 2850

 atacctaacc cttcagcctc atcaaagaca gatgctagtg tgccagtggc 2900

 tgtaactccc tcccctttaa catctttatt gaccacagcc actttagaaa 2950

 agcttcctgt accccaggtc agtgcaacta cagcacctgc tggatcagct 3000

 ccaccctcga gcactttgcc agcagcttct agccttaaaa ccccaggaac 3050

 ttctttaaac atgaatggac ccactttaag accaacctct agtatccctg 3100

 ctaataatcc tttagtgact cagctgcttc aaggcaaaga tgttcccatg 3150

 gagcaaattc tgcctaaacc tctcaccaaa gttgaaatga aaacggttcc 3200

 actgactgca aaagaggaaa gggggatggg agcgctcata gctaccaaca 3250

 caacagaaaa tagcaccaga gaggaagtta atgagagaca gtcccatcca 3300

 gctacgcagc agcagctggg caaaaccttg caaagtaagc agctccccca 3350

 ggttccaagg ccccttcagc tcttttcagc taaggagctg agggactcca 3400

 gcattgacac acaccaatac cacgaaggac taagtaaagc aacccaagat 3450

 cagatccttc agactctcat tcagagggtt cggaggcaga atcttctctc 3500

 agttgtgccg ccctcacagt tcaacttcgc tcactcaggt ttccagctgg 3550

 aagacatctc cacaagccag aggttcatgc tgggttttgc tggcagaagg 3600

 acatccaaac ctgcaatggc agggcactac ttactgaata tttctaccta 3650

 cggccggggc tcagagagct ttaggaggac ccattctgta aaccctgaag 3700

 atcgtttttg tctaagcagc cccactgaag ccttgaaaat gggatataca 3750

 gactgtaaaa atgcaacagg agagagtagc agcagcaaag aagatgacac 3800

 tgatgaggaa agtactggtg atgagcagga atctgtcaca gtgaaagagg 3850

 agccccaggt ttcccagagt gctggcaagg gtgacacaag ttcaggacct 3900

 cacagcaggg aaactctatc taccagtgat tgcttagcta gcaagaatgt 3950

 gaaggctgag ataccattga atgagcaaac cactttaagt aaggagaatt 4000

 acctgttcac tagaggccaa acatttgatg aaaagaccct agccagagat 4050

 ttaattcagg cagcacagaa gcagatggct catgcagtga gaggtaaggc 4100

 aatccgtagc agccccgagc ttttcagttc tactgttctt cctctgcctg 4150

 cagacagccc cacccaccag cccctactcc ttccacccct gcaaaccccg 4200

 aagttgtatg gaagccccac ccagataggg ccaagctata gaggcatgat 4250

 caatgtctcc acctcatctg acatggacca taactctgct gtaccaggta 4300

 gccaggtatc tagcaatgta ggtgatgtca tgtcattttc agtgactgtc 4350

 actaccatcc ctgctagcca agctatgaat cccagcagcc atggccagac 4400

 cattcctgtt caggcgttct ccgaagagaa cagcatagag ggcacgcctt 4450

 cgaaatgtta ctgccgcttg aaagccatga tcatgtgcaa aggctgtggc 4500

 gctttctgcc atgatgattg catcggcccc tccaaactgt gcgtctcctg 4550

 ccttgtcgtt cggtaatgag actagaaaga gatacactgt aaaggagggg 4600

 gaagggaagg gttgaccagt tgggtttttt gcgtcctttt ggaatcacag 4650

 aaataaacaa gtaggtttca gttgtcttca gagacaaatg ttacttaatc 4700

 aggaatacaa agtacagatt ttttacattt tagaggaaga gcaccttgta 4750

 tagtaagtct aagtcaagca agactttgtg aatttgtgac aagtttgcac 4800

 ttacaaaatc atgtaaatat gtcacatttt gtttaacatt atttttccaa 4850

 gtgtttaggt aataatgtat tactttgaat tcagattaat gttctactac 4900

 ttgtgactga gaaaagttta atgccggcat ggtaaaagga agctgtctcc 4950

 cttctgacat ttcctaggaa gctaggaaaa ggaaagtgaa ggaatggtct 5000

 aaagaaatga ccattcacac tgattttgtc tggacagtct ggccgcaggt 5050

 tattcataga ttattcagcc tttgcaggac ttggattcag ggttttactc 5100

 agtcccttta ccttaggtgg aatcttctta aattgaaatt tttggtaagg 5150

 aattcatttc acaggtagtg tttcagactc tgaaagccct gacttggttc 5200

 ttggcttcta ctgtactagt tactagttac tggtactgtt gccaagcaat 5250

 ctgcttggaa tttgtggatc cctgctgttc cctaatccca ccccctgccc 5300

 tgagacagtg aatgtagtcc gtgaagggag tgcctctctg ggaccccctg 5350

 tgttgttaca ggctgtgcag tgcaacaatt ccagcaaaaa taccctatcc 5400

 ccgcacttag tcattcgtgg taactaacaa ttttgaaata ctcatataaa 5450

 atgaacagga aagtgttagt gattgggtga tttgagctac atcttgttga 5500

 gcaaggggag tgaaaccaca gaaactgtta aattgaacgt aaataacttt 5550

 ggaaaacagt tttgacacta gaacaaggtc gcttctcttt tcctcttctc 5600

 tcccaacctg ttaacctagt gctagatagt cagctgctgt tgcaggtaga 5650

 aaagctcacc aatgccacat ttgttcattc tgttcaacct gttttgacct 5700

 cccaggcatc tgaacaggat gacatcatct tattatatct tactttacac 5750

 atacgtgtat gtacacacac acacacaata caagacattt ttcctgtttt 5800

 agaaaatata gcccttgttt ggattactgc tgtctgagca ctagaaattt 5850

 ctaatggaaa gaggcctctg aatggctaag ggaacatctg gaaaggaagg 5900

 aaaatgagcc ctaaaggttt tttggttgct tgtttttgtt tctttttctt 5950

 tcttgtttcc ttttttgttt ttaaatcctt ctctagtgac tgaagaaatt 6000

 gtgagtacat aatatttagg tcatggttaa ggaacattaa aataaacctg 6050

 cagtttaaca gaattttgta ttaaatgggg gagtgtcaat ttgcatcatt 6100

 tgcatattga tttcaagtct cctaatttgg aatgggtaaa gtacaaatgt 6150

 taatgcaaca tagtacagtt gtatttgtcc ttcatattca ggatgtgata 6200

 tttacaaaat gcagaacagt ttaaacttgt taagtcacat tccagattag 6250

 gagaaaatgg gcaataatca tctctgtttt gcccccattc tactacccac 6300

 cactgcccac cccaccccca catcacacac tcttcgatgc tttcccacag 6350

 cccctgctcc gctcctctcc gtaagaaact cacttcactg tttttcactt 6400

 ttcacttctg gcttttttgt ggcccaaggc caatatagga ttaatatctg 6450

 tgttccagct tcagccagaa cgatatgtct gtccatcttt ctcctttctt 6500

 ccagcacaca cagctaagag ataagaaggc tgcaaggatt ggggataagg 6550

 agtatatttt caagccaaga accagtagaa aacagaaata atggtgctcc 6600

 caaatattca gtaccttggg caatccagga agggtttaaa gagacctgtt 6650

 gctgcataga actctccctg ccctacccct taactccacc ttagtgccag 6700

 ggccgagggc tggtctgcat gctggaagag gttgagagtt ttggaattga 6750

 ttccatgcta aatgtcagtt accagtttgg attgatgaaa gtgatttttc 6800

 tgctttacct ttttcctgtc agaaaggttt tcctctgtgc tacccttaac 6850

 ttagggatga acagactata actaggaaag gaggaaaggt atcagggatt 6900

 tttaagtccg tttagagagc aaaccatatt gtgcctcttc atcttgaccc 6950

 aggctcttat agataggtcc taaacattgc tgttcactag attatcttaa 7000

 caaataatac tcagctaaat atttgcattt aggaatactc ctaaaacaga 7050

 tattgccaac tagatacact gcctcaatct tgaccagaca agagaacagt 7100

 taagttctct cagttgggta gtaacttgaa taccagtcta tttatcagtt 7150

 ggtttcaaca cagaggtttc aagtggaaag ccattcatct taaaagctga 7200

 acagaaaaat taaaaaaaaa aaaaacacat tacaatctgg ccttttagaa 7250

 aatgaagcag tagaaacaaa acctttatta gtatggtatt ccagcagcac 7300

 ctttaaagca atctttacct tagttttttg agttgtttta cctttcatcc 7350

 caatctgaaa agttttaata aatgctgagc ttattcttag ggtatgacct 7400

 ggcattattt ccagtgacta gtcaggcatt atgcctgatg catacgcctc 7450

 ccgtgcaccc ctatctagcc ttcagatgtc ctccactgca ggtcacccca 7500

 ggagatagca tcaataaata gtctcagtct tgtttataaa gattctaagt 7550

 tgtctagtaa ataagtctcc ctgaatctta aataattttg gagaattaga 7600

 attctccatc ctattaaaca gaaagtaaag ccaaatagcc tggagttgtt 7650

 tgtcctactt gttccataac ccctatgctc aagatactga agctatctgt 7700

 ggtatttcat gtaacatttc taagaataag agctggcaaa tgggaaactt 7750

 ggggtggaga gagcatactt attgggctgt gaaggcatac ggatgtacat 7800

 gttttagagc ttatctcaga tttaaatagc caaaggaaga cctcattgcc 7850

 ttccaggtga aggtgcaaag tcatacatat taatgacctg acagttaaca 7900

 ttctgttgtt tattattgcc tttctccacc ttagagagcc ataaataact 7950

 ctctggtgaa gtgatttgct ataatggggg tgaggagtgg ggagacttct 8000

 ctggtcatta cactgctatt tatttctaga actcactatc agtgagcagt 8050

 gccagagtgt tttctctttg acctagaggt ttcacatcat agcaaggagg 8100

 gaaaagtctc cccatctcct tacaactgtg tgctaagtaa gtaacttggc 8150

 caagggtagt tttcagctca atttatagaa tagtccaaag agactttgag 8200

 aaacatggtg ataggcaggg gcctttccta ccatgtttca atacctacaa 8250

 acctattgaa agagaacagt aggtaaaaca tttcctaaag ttgaagcaat 8300

 agcttcgtag attcttggtt actttatttt ttttaatgct ttacatttga 8350

 tacaactatt gaagatcaat tttaaaaata gctttccagt aatatatttt 8400

 aagtaatata tattttaata tctgtaaaaa gtgacagtgg aagactttga 8450

 atttctcata tatggtatgt ttgatgtagg acctcactgt taaggcacaa 8500

 attatttcaa aggaagttac tctaaagaca ctcagattat ttcagaaaaa 8550

 tgcaataagg ggaatagttt tggggtttat tttttatttt aaaagaaaat 8600

 tgacttattt accacaagct atttttttcc cttctggctg taaggtttgt 8650

 acagactggt ttggtaaatg ctaaactttt gtgtcttttg cctttttaaa 8700

 ggaattgtta acattggaat tgagggtatg tacagagaag ttggtgtcaa 8750

 caccatttaa aaagtcatat tttttcacaa atatagaaaa tcattttaca 8800

 taagaatttt aagtatttgc aataaatata tgtatataga ttgtatgtat 8850

 tcctatattc ttatttttca ttttattatt aagtaaaaga tcattaaaag 8900

 tgaaaataaa aaccttggag ttttttggtg aatcttgagg tttaacatac 8950

 atctgagagt ggcgtgggta agagtcctca gttactgcct tatactccta 9000

 tgggatggtt cccacagatt gtatggaaga gagtaaaatg aggaacttgg 9050

 tgataaatca gggtagtgta tttcttttgg aatttaagta aaactgatta 9100

 tgattttcct tatctgtcta tatccatgtt ctctctcata atctgttccg 9150

 tgctcataac ct 9162

<210> 4344
<211> 1334
<212> PRT
<213> Homo sapien

<400> 4344
 Met Val Ser Gln Ile Pro Arg Val Leu Arg Thr Ala Ala Ala Ala
   1               5                  10                  15

 Val Met Val Ala Ala Thr Arg Arg Glu Lys Arg Ala Gly Gly Lys
                  20                  25                  30

 Gly Lys Tyr Arg Arg Pro Pro Arg Ser Gln Ala Ala His His Pro
                  35                  40                  45

 Pro Phe Gln Gln Val Lys Ser Phe Leu His His Arg Ser Thr Ala
                  50                  55                  60

 Lys Lys Ala Leu Lys Gln Ala Leu Lys Gln Gln Gln Gln Lys Lys
                  65                  70                  75

 Gln Gln Gln Gln Cys Arg Pro Ser Ile Ser Ile Ser Ser Asn Gln
                  80                  85                  90

 His Leu Ser Leu Lys Thr Val Lys Ala Ala Ser Asp Ser Val Pro
                  95                 100                 105

 Ala Lys Pro Ala Thr Trp Glu Gly Lys Gln Ser Asp Gly Gln Thr
                 110                 115                 120

 Gly Ser Pro Gln Asn Ser Asn Ser Ser Phe Ser Ser Ser Val Lys
                 125                 130                 135

 Val Glu Asn Thr Leu Leu Gly Leu Gly Lys Lys Ser Phe Gln Arg
                 140                 145                 150

 Ser Glu Arg Leu His Thr Arg Gln Met Lys Arg Thr Lys Cys Ala
                 155                 160                 165

 Asp Ile Asp Val Glu Thr Pro Asp Ser Ile Leu Val Asn Thr Asn
                 170                 175                 180

 Leu Arg Ala Leu Ile Asn Lys His Thr Phe Ser Val Leu Pro Gly
                 185                 190                 195

 Asp Cys Gln Gln Arg Leu Leu Leu Leu Leu Pro Glu Val Asp Arg
                 200                 205                 210

 Gln Val Gly Pro Asp Gly Leu Met Lys Leu Asn Gly Ser Ala Leu
                 215                 220                 225

 Asn Asn Glu Phe Phe Thr Ser Ala Ala Gln Gly Trp Lys Glu Arg
                 230                 235                 240

 Leu Ser Glu Gly Glu Phe Thr Pro Glu Met Gln Val Arg Ile Arg
                 245                 250                 255

 Gln Glu Ile Glu Lys Glu Lys Lys Val Glu Pro Trp Lys Glu Gln
                 260                 265                 270

 Phe Phe Glu Ser Tyr Tyr Gly Gln Ser Ser Gly Leu Ser Leu Glu
                 275                 280                 285

 Asp Ser Lys Lys Leu Thr Ala Ser Pro Ser Asp Pro Lys Val Lys
                 290                 295                 300

 Lys Thr Pro Ala Glu Gln Pro Lys Ser Met Pro Val Ser Glu Ala
                 305                 310                 315

 Ser Leu Ile Arg Ile Val Pro Val Val Ser Gln Ser Glu Cys Lys
                 320                 325                 330

 Glu Glu Ala Leu Gln Met Ser Ser Pro Gly Arg Lys Glu Glu Cys
                 335                 340                 345

 Glu Ser Gln Gly Glu Val Gln Pro Asn Phe Ser Thr Ser Ser Glu
                 350                 355                 360

 Pro Leu Leu Ser Ser Ala Leu Asn Thr His Glu Leu Ser Ser Ile
                 365                 370                 375

 Leu Pro Ile Lys Cys Pro Lys Asp Glu Asp Leu Leu Glu Gln Lys
                 380                 385                 390

 Pro Val Thr Ser Ala Glu Gln Glu Ser Glu Lys Asn His Leu Thr
                 395                 400                 405

 Thr Ala Ser Asn Tyr Asn Lys Ser Glu Ser Gln Glu Ser Leu Val
                 410                 415                 420

 Thr Ser Pro Ser Lys Pro Lys Ser Pro Gly Val Glu Lys Pro Ile
                 425                 430                 435

 Val Lys Pro Thr Ala Gly Ala Gly Pro Gln Glu Thr Asn Met Lys
                 440                 445                 450

 Glu Pro Leu Ala Thr Leu Val Asp Gln Ser Pro Glu Ser Leu Lys
                 455                 460                 465

 Arg Lys Ser Ser Leu Thr Gln Glu Glu Ala Pro Val Ser Ala Gly
                 470                 475                 480

 Arg Arg Gly His Val Ser Leu Arg Ile Ala Ser Thr Ser Ser His
                 485                 490                 495

 Phe Arg Ser His His Ser Pro Phe Ser Ile Glu Gly Thr Glu Ser
                 500                 505                 510

 Arg Cys Glu Lys Tyr His Leu Ser Arg Ser Arg Ser Pro Glu Ser
                 515                 520                 525

 Pro Pro Cys Arg Phe Ile His Arg Arg Ser Leu Pro Gly Leu Val
                 530                 535                 540

 Phe Gln Ser Pro Ser Leu Val Leu Thr Glu Gln Glu Pro Glu Leu
                 545                 550                 555

 Leu Gln Thr Ser Lys Gln Lys Pro Asn Trp Ser Lys His Arg Gly
                 560                 565                 570

 Gln Gln Leu Pro Leu Pro Ala Ala Ala Ala Ala Ala Ala Ser Val
                 575                 580                 585

 Gly Gly Thr Ile Pro Gly Pro Gly Pro Gly Gly Gly Gln Gly Pro
                 590                 595                 600

 Gly Glu Gly Gly Glu Gly Gln Thr Ala Arg Gly Gly Ser Pro Gly
                 605                 610                 615

 Ser Asp Arg Val Ser Glu Thr Gly Lys Gly Pro Thr Leu Glu Leu
                 620                 625                 630

 Ala Gly Thr Gly Ser Arg Gly Gly Thr Arg Glu Leu Leu Pro Cys
                 635                 640                 645

 Gly Pro Glu Thr Gln Pro Gln Ser Glu Thr Lys Thr Thr Pro Ser
                 650                 655                 660

 Gln Ala Gln Pro His Ser Val Ser Gly Ala Gln Leu Gln Gln Thr
                 665                 670                 675

 Pro Pro Val Pro Pro Thr Pro Ala Val Ser Gly Ala Cys Thr Ser
                 680                 685                 690

 Val Pro Ser Pro Ala His Ile Glu Lys Leu Asp Asn Glu Lys Leu
                 695                 700                 705

 Asn Pro Thr Arg Ala Thr Ala Thr Val Ala Ser Val Ser His Pro
                 710                 715                 720

 Gln Gly Pro Ser Ser Cys Arg Gln Glu Lys Ala Pro Ser Pro Thr
                 725                 730                 735

 Gly Pro Ala Leu Ile Ser Gly Ala Ser Pro Val His Cys Ala Ala
                 740                 745                 750

 Asp Gly Thr Val Glu Leu Lys Ala Gly Pro Ser Lys Asn Ile Pro
                 755                 760                 765

 Asn Pro Ser Ala Ser Ser Lys Thr Asp Ala Ser Val Pro Val Ala
                 770                 775                 780

 Val Thr Pro Ser Pro Leu Thr Ser Leu Leu Thr Thr Ala Thr Leu
                 785                 790                 795

 Glu Lys Leu Pro Val Pro Gln Val Ser Ala Thr Thr Ala Pro Ala
                 800                 805                 810

 Gly Ser Ala Pro Pro Ser Ser Thr Leu Pro Ala Ala Ser Ser Leu
                 815                 820                 825

 Lys Thr Pro Gly Thr Ser Leu Asn Met Asn Gly Pro Thr Leu Arg
                 830                 835                 840

 Pro Thr Ser Ser Ile Pro Ala Asn Asn Pro Leu Val Thr Gln Leu
                 845                 850                 855

 Leu Gln Gly Lys Asp Val Pro Met Glu Gln Ile Leu Pro Lys Pro
                 860                 865                 870

 Leu Thr Lys Val Glu Met Lys Thr Val Pro Leu Thr Ala Lys Glu
                 875                 880                 885

 Glu Arg Gly Met Gly Ala Leu Ile Ala Thr Asn Thr Thr Glu Asn
                 890                 895                 900

 Ser Thr Arg Glu Glu Val Asn Glu Arg Gln Ser His Pro Ala Thr
                 905                 910                 915

 Gln Gln Gln Leu Gly Lys Thr Leu Gln Ser Lys Gln Leu Pro Gln
                 920                 925                 930

 Val Pro Arg Pro Leu Gln Leu Phe Ser Ala Lys Glu Leu Arg Asp
                 935                 940                 945

 Ser Ser Ile Asp Thr His Gln Tyr His Glu Gly Leu Ser Lys Ala
                 950                 955                 960

 Thr Gln Asp Gln Ile Leu Gln Thr Leu Ile Gln Arg Val Arg Arg
                 965                 970                 975

 Gln Asn Leu Leu Ser Val Val Pro Pro Ser Gln Phe Asn Phe Ala
                 980                 985                 990

 His Ser Gly Phe Gln Leu Glu Asp Ile Ser Thr Ser Gln Arg Phe
                 995                1000                1005

 Met Leu Gly Phe Ala Gly Arg Arg Thr Ser Lys Pro Ala Met Ala
                1010                1015                1020

 Gly His Tyr Leu Leu Asn Ile Ser Thr Tyr Gly Arg Gly Ser Glu
                1025                1030                1035

 Ser Phe Arg Arg Thr His Ser Val Asn Pro Glu Asp Arg Phe Cys
                1040                1045                1050

 Leu Ser Ser Pro Thr Glu Ala Leu Lys Met Gly Tyr Thr Asp Cys
                1055                1060                1065

 Lys Asn Ala Thr Gly Glu Ser Ser Ser Ser Lys Glu Asp Asp Thr
                1070                1075                1080

 Asp Glu Glu Ser Thr Gly Asp Glu Gln Glu Ser Val Thr Val Lys
                1085                1090                1095

 Glu Glu Pro Gln Val Ser Gln Ser Ala Gly Lys Gly Asp Thr Ser
                1100                1105                1110

 Ser Gly Pro His Ser Arg Glu Thr Leu Ser Thr Ser Asp Cys Leu
                1115                1120                1125

 Ala Ser Lys Asn Val Lys Ala Glu Ile Pro Leu Asn Glu Gln Thr
                1130                1135                1140

 Thr Leu Ser Lys Glu Asn Tyr Leu Phe Thr Arg Gly Gln Thr Phe
                1145                1150                1155

 Asp Glu Lys Thr Leu Ala Arg Asp Leu Ile Gln Ala Ala Gln Lys
                1160                1165                1170

 Gln Met Ala His Ala Val Arg Gly Lys Ala Ile Arg Ser Ser Pro
                1175                1180                1185

 Glu Leu Phe Ser Ser Thr Val Leu Pro Leu Pro Ala Asp Ser Pro
                1190                1195                1200

 Thr His Gln Pro Leu Leu Leu Pro Pro Leu Gln Thr Pro Lys Leu
                1205                1210                1215

 Tyr Gly Ser Pro Thr Gln Ile Gly Pro Ser Tyr Arg Gly Met Ile
                1220                1225                1230

 Asn Val Ser Thr Ser Ser Asp Met Asp His Asn Ser Ala Val Pro
                1235                1240                1245

 Gly Ser Gln Val Ser Ser Asn Val Gly Asp Val Met Ser Phe Ser
                1250                1255                1260

 Val Thr Val Thr Thr Ile Pro Ala Ser Gln Ala Met Asn Pro Ser
                1265                1270                1275

 Ser His Gly Gln Thr Ile Pro Val Gln Ala Phe Ser Glu Glu Asn
                1280                1285                1290

 Ser Ile Glu Gly Thr Pro Ser Lys Cys Tyr Cys Arg Leu Lys Ala
                1295                1300                1305

 Met Ile Met Cys Lys Gly Cys Gly Ala Phe Cys His Asp Asp Cys
                1310                1315                1320

 Ile Gly Pro Ser Lys Leu Cys Val Ser Cys Leu Val Val Arg
                1325                1330

<210> 4345
<211> 2861
<212> DNA
<213> Homo sapien

<400> 4345
 gttgctgctg ctcggcctgg cccgcggcgc cgcgggagcg cagggccccg 50

 acggtttaga cgtctgtgcc acttgccatg aacatgccac atgccagcaa 100

 agagaaggga agaagatctg tatttgcaac tatggatttg tagggaacgg 150

 gaggactcag tgtgttgata aaaatgagtg ccagtttgga gccactcttg 200

 tctgtgggaa ccacacatct tgccacaaca cccccggggg cttctattgc 250

 atttgcctgg aaggatatcg agccacaaac aacaacaaga cattcattcc 300

 caacgatggc accttttgta cagacataga tgagtgtgaa gcttctggcc 350

 tgtgcaggca tggagggcga tgcgtgaaca ctcatgggag ctttgaatgc 400

 tactgtatgg atggatactt gccaaggaat ggacctgaac ctttccaccc 450

 gaccaccgat gccacatcat gcacagaaat agactgtggt acccctcctg 500

 aggttccaga tggctatatc ataggaaatt atacgtctag tctgggcagc 550

 caggttcgtt atgcttgcag agaaggattc ttcagtgttc cagaagatac 600

 agtttcaagc tgcacaggcc tgggcacatg ggagtcccca aaattacatt 650

 gccaagagat caactgtggc aaccctccag aaatgcggca cgccatcttg 700

 gtaggaaatc acagctccag gctgggcggt gtggctcgct atgtctgtca 750

 agagggcttt gagagccctg gaggaaagat cacttctgtt tgcacagaga 800

 aaggcacctg gagagaaagt actttaacat gcacagaaat tctgacaaag 850

 attaatgatg tatcactgtt taatgatacc tgtgtgagat ggcaaataaa 900

 ctcaagaaga ataaacccca agatctcata tgtgatatcc ataaaaggac 950

 aacggttgga ccctatggaa tcagttcgtg aggagacagt caacttgacc 1000

 acagacagca ggaccccaga agtgtgccta gccctgtacc caggcaccaa 1050

 ctacaccgtg aacatctcca cagcacctcc caggcgctcg atgccagccg 1100

 tcatcggttt ccagacagct gaagttgatc tcttagaaga tgatggaagt 1150

 ttcaatattt caatatttaa tgaaacttgt ttgaaattga acaggcgttc 1200

 taggaaagtt ggatcagaac acatgtacca atttaccgtt ctgggtcaga 1250

 ggtggtatct ggctaacttt tctcatgcaa catcgtttaa cttcacaacg 1300

 agggaacaag tgcctgtagt gtgtttggat ctgtacccta cgactgatta 1350

 tacggtgaat gtgaccctgc tgagatctcc taagcggcac tcagtgcaaa 1400

 taacaatagc aactccccca gcagtaaaac agaccatcag taacatttca 1450

 ggatttaatg aaacctgctt gagatggaga agcatcaaga cagctgatat 1500

 ggaggagatg tatttattcc acatttgggg ccagagatgg tatcagaagg 1550

 aatttgccca ggaaatgacc tttaatatca gtagcagcag ccgagatccc 1600

 gaggtgtgct tggacctacg tccgggtacc aactacaatg tcagtctccg 1650

 ggctctgtct tcggaacttc ctgtggtcat ctccctgaca acccagataa 1700

 cagagcctcc cctcccggaa gtagaatttt ttacggtgca cagaggacct 1750

 ctaccacgcc tcagactgag gaaagccaag gagaaaaatg gaccaatcag 1800

 ttcatatcag gtgttagtgc ttcccctggc cctccaaagc acattttctt 1850

 gtgattctga aggcgcttcc tccttcttta gcaacgcctc tgatgctgat 1900

 ggatacgtgg ctgcagaact actggccaaa gatgttccag atgatgccat 1950

 ggagatacct ataggagaca ggctgtacta tggggaatat tataatgcac 2000

 ccttgaaaag agggagtgat tactgcatta tattacgaat cacaagtgaa 2050

 tggaataaga ttcgtcactc atgctgctgc agatggcggg tgttggactg 2100

 ggttccctgg ctgttgtgat cattcttaca ttcctctcct tctcagcggt 2150

 gtgatggcag atggacactg agtggggagg atgcactgct gctgggcagg 2200

 tgttctggca gcttctcagg tgcccgcaca gaggctccgt gtgacttccg 2250

 tccagggagc atgtgggcct gcaactttct ccattcccag ctgggcccca 2300

 ttcctggatt taagatggtg gctatccctg aggagtcacc ataaggagaa 2350

 aactcaggaa ttctgagtct tccctgctac aggaccagtt ctgtgcaatg 2400

 aacttgagac tcctgatgta cactgtgata ttgaccgaag gctacataca 2450

 gatctgtgaa tcttggctgg gacttcctct gagtgatgcc tgagggtcag 2500

 ctcctctaga cattgactgc aagagaatct ctgcaacctc ctatataaaa 2550

 gcatttctgt taattcattc agaatccatt ctttacaata tgcagtgaga 2600

 tgggcttaag tttgggctag agtttgactt tatgaaggaa gtcattgaaa 2650

 aagagaacag tgacgtaggc aaatgtttca agcactttag aaacagtact 2700

 tttcctataa ttagttgata tactaatgag aaaatatact agcctggcca 2750

 tgccaataag tttcctgctg tgtctgttag gcagcattgc tttgatgcaa 2800

 tttctattgt cctatatatt caaaagtaat gtctacattc cagtaaaaat 2850

 atcccgtaat t 2861

<210> 4346
<211> 570
<212> PRT
<213> Homo sapien

<400> 4346
 Met Asp Gly Tyr Leu Pro Arg Asn Gly Pro Glu Pro Phe His Pro
   1               5                  10                  15

 Thr Thr Asp Ala Thr Ser Cys Thr Glu Ile Asp Cys Gly Thr Pro
                  20                  25                  30

 Pro Glu Val Pro Asp Gly Tyr Ile Ile Gly Asn Tyr Thr Ser Ser
                  35                  40                  45

 Leu Gly Ser Gln Val Arg Tyr Ala Cys Arg Glu Gly Phe Phe Ser
                  50                  55                  60

 Val Pro Glu Asp Thr Val Ser Ser Cys Thr Gly Leu Gly Thr Trp
                  65                  70                  75

 Glu Ser Pro Lys Leu His Cys Gln Glu Ile Asn Cys Gly Asn Pro
                  80                  85                  90

 Pro Glu Met Arg His Ala Ile Leu Val Gly Asn His Ser Ser Arg
                  95                 100                 105

 Leu Gly Gly Val Ala Arg Tyr Val Cys Gln Glu Gly Phe Glu Ser
                 110                 115                 120

 Pro Gly Gly Lys Ile Thr Ser Val Cys Thr Glu Lys Gly Thr Trp
                 125                 130                 135

 Arg Glu Ser Thr Leu Thr Cys Thr Glu Ile Leu Thr Lys Ile Asn
                 140                 145                 150

 Asp Val Ser Leu Phe Asn Asp Thr Cys Val Arg Trp Gln Ile Asn
                 155                 160                 165

 Ser Arg Arg Ile Asn Pro Lys Ile Ser Tyr Val Ile Ser Ile Lys
                 170                 175                 180

 Gly Gln Arg Leu Asp Pro Met Glu Ser Val Arg Glu Glu Thr Val
                 185                 190                 195

 Asn Leu Thr Thr Asp Ser Arg Thr Pro Glu Val Cys Leu Ala Leu
                 200                 205                 210

 Tyr Pro Gly Thr Asn Tyr Thr Val Asn Ile Ser Thr Ala Pro Pro
                 215                 220                 225

 Arg Arg Ser Met Pro Ala Val Ile Gly Phe Gln Thr Ala Glu Val
                 230                 235                 240

 Asp Leu Leu Glu Asp Asp Gly Ser Phe Asn Ile Ser Ile Phe Asn
                 245                 250                 255

 Glu Thr Cys Leu Lys Leu Asn Arg Arg Ser Arg Lys Val Gly Ser
                 260                 265                 270

 Glu His Met Tyr Gln Phe Thr Val Leu Gly Gln Arg Trp Tyr Leu
                 275                 280                 285

 Ala Asn Phe Ser His Ala Thr Ser Phe Asn Phe Thr Thr Arg Glu
                 290                 295                 300

 Gln Val Pro Val Val Cys Leu Asp Leu Tyr Pro Thr Thr Asp Tyr
                 305                 310                 315

 Thr Val Asn Val Thr Leu Leu Arg Ser Pro Lys Arg His Ser Val
                 320                 325                 330

 Gln Ile Thr Ile Ala Thr Pro Pro Ala Val Lys Gln Thr Ile Ser
                 335                 340                 345

 Asn Ile Ser Gly Phe Asn Glu Thr Cys Leu Arg Trp Arg Ser Ile
                 350                 355                 360

 Lys Thr Ala Asp Met Glu Glu Met Tyr Leu Phe His Ile Trp Gly
                 365                 370                 375

 Gln Arg Trp Tyr Gln Lys Glu Phe Ala Gln Glu Met Thr Phe Asn
                 380                 385                 390

 Ile Ser Ser Ser Ser Arg Asp Pro Glu Val Cys Leu Asp Leu Arg
                 395                 400                 405

 Pro Gly Thr Asn Tyr Asn Val Ser Leu Arg Ala Leu Ser Ser Glu
                 410                 415                 420

 Leu Pro Val Val Ile Ser Leu Thr Thr Gln Ile Thr Glu Pro Pro
                 425                 430                 435

 Leu Pro Glu Val Glu Phe Phe Thr Val His Arg Gly Pro Leu Pro
                 440                 445                 450

 Arg Leu Arg Leu Arg Lys Ala Lys Glu Lys Asn Gly Pro Ile Ser
                 455                 460                 465

 Ser Tyr Gln Val Leu Val Leu Pro Leu Ala Leu Gln Ser Thr Phe
                 470                 475                 480

 Ser Cys Asp Ser Glu Gly Ala Ser Ser Phe Phe Ser Asn Ala Ser
                 485                 490                 495

 Asp Ala Asp Gly Tyr Val Ala Ala Glu Leu Leu Ala Lys Asp Val
                 500                 505                 510

 Pro Asp Asp Ala Met Glu Ile Pro Ile Gly Asp Arg Leu Tyr Tyr
                 515                 520                 525

 Gly Glu Tyr Tyr Asn Ala Pro Leu Lys Arg Gly Ser Asp Tyr Cys
                 530                 535                 540

 Ile Ile Leu Arg Ile Thr Ser Glu Trp Asn Lys Ile Arg His Ser
                 545                 550                 555

 Cys Cys Cys Arg Trp Arg Val Leu Asp Trp Val Pro Trp Leu Leu
                 560                 565                 570

<210> 4347
<211> 2586
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 358-483
<223> Unknown base

<400> 4347
 tgcaaacatg agaactaatg aaccaaggcg gctgccacca ggaaggaaca 50

 gaacgcaggc attcaaccat gacgtctgca cagtgttagt aacatgtcat 100

 tgtggtttcg ttctcactgt ggtaaaattt atttctgagc acttaaactg 150

 tgttgcatac ccctaatttt ttttttttct gtatcttcct tgccctcaaa 200

 taccctgagg tgataaactg ttccagttgt agccaactac cactgcgccc 250

 ggccttaaat aaaatattgt agtcattaat ggtgtgtttg aattgaagag 300

 ataccaggag atagaggtga agtgcagtac ttttattctt taagaatata 350

 gtctttannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngtttccc attcatatta 500

 actccatctt ttaaaaatgt catgattaca aagtgaaaag atttggcttt 550

 cttagaggct caatcacaga ggtgaaagtg accttggaaa tcatatactc 600

 tatccccatg ttacacagat tagaaaaact gaggttatgg cactgactta 650

 ggcaccccca gcaaggcaac ccagggacta caactggcaa tcccaactcc 700

 tgggctaggg ctttttctac ctttttttgc attggcctct taaagaggca 750

 atgaatacta attcctggca tcagaaaaaa aaaaaggcat gaggtgggag 800

 gattcttttt tccctgatgg gaaacagtga ataagaaaaa tctcatcatt 850

 cgatggaaga ggtgacttaa taattttatt aatgaatttg atgtcccatg 900

 ttttgtagtt ttgttatcat tgaaccatgg gggctggaat ctgcctaaat 950

 aattttatct tggtagccag caattatgtt ggtattttat gtgggccttc 1000

 ccagattttc atattaatga aatgactaat agtcgtactt aagaggtaac 1050

 tctactaaag cagaatgaga tctaatatgt tgtggaaata aaagagtttg 1100

 cagtggaatg atactctcac tccgtgcttg taaaattgag ttctattcaa 1150

 gacggaactg ctatgactgg cctattcaag gcttcatatt tttatacaga 1200

 ctatttcaca gaccatagat ttattttaaa agggaaaatc tcacacataa 1250

 ttaagcagtg gaaaatgtgc tcaatgctat ggtgcgtcag gccctctgtc 1300

 taccaggttt ctcccctttc tgcagagctg tggaccctgt acgtaccaaa 1350

 caggtgaact tggtccatct ttccttcttc ctttttttgc acatttgcat 1400

 ttatatcttc ctgtactaaa agaaacaaat tatttataat tggggtgaca 1450

 atataaagga acaaaagatg gggcaatagt tgcttcctag ctggagctgt 1500

 aagtccatgt tacagaaact cactatttaa aaagttttaa aagatttatg 1550

 aaccttgtcc tacaattcgc tgaatactta tttgtctttt aaactcccct 1600

 cggtgtatgg atcatcttcg tcagaatgcc gttgtttcat tgtgaatcag 1650

 gggaaaatgt taatcatttg gagactgttt tcttattacc aaatgtacaa 1700

 tccataagac aactgaaagc aacaactgct gggttcactg acaaagatta 1750

 taaaaatcat cacgttcaaa gtagagtttt tagccaaggt caagaactaa 1800

 cctggggctg agtcagcgtc tctacccact taaataacag cgtaaagatc 1850

 tttcactaaa ttcgttatgt ggtctgtctg gatgtaaacc tatatatttc 1900

 cttttgaaac agaatcatat cctgcagact cttggcactc ctgcatagct 1950

 ttgaccgaat gttcactctc atcgtaatgg aagatttcta tctatgcaga 2000

 taatacatgt ttttaaatac tgttttctgt ttagtcctca atcttcctaa 2050

 ctcaaattgg ggactgagga gagagaaagg tggttacccc tgttaccgtg 2100

 ccatattctt cttgctgctt ttcaacccca cgtgattgtt gattgacggt 2150

 tctgctataa tgtgcgtgcc cttcaagttt cagaaaactt tcccaatcat 2200

 ttcacttcaa tcttaattga acccaagagt caaagttatt attttctccg 2250

 aacgtgtttg tgatcttctg ttatattttg gggcatgtta cctttatggt 2300

 atataagctg tagtgcatac tctttgtatt gcaaaaaact ggtcagtaat 2350

 ttatgtacat gtattccaca ttttagtgtg cttgaagtga caatccatag 2400

 tttgtagtag tttgttattt gtcaacttta ccctgtgttt taaggacatc 2450

 taaacattcc ttgtcctatc aagatgacaa aagcagaatg taattttttt 2500

 ttggaagctt cgtgattacc tgtaacaagt tctgttttta aaacgaatac 2550

 aaataaagtt agtaactatt tttaaatcag aaaaaa 2586

<210> 4348
<211> 54
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 358-483
<223> Unknown amino acid

<400> 4348
 Ala Asn Met Arg Thr Asn Glu Pro Arg Arg Leu Pro Pro Gly Arg
   1               5                  10                  15

 Asn Arg Thr Gln Ala Phe Asn His Asp Val Cys Thr Val Leu Val
                  20                  25                  30

 Thr Cys His Cys Gly Phe Val Leu Thr Val Val Lys Phe Ile Ser
                  35                  40                  45

 Glu His Leu Asn Cys Val Ala Tyr Pro
                  50

<210> 4349
<211> 3280
<212> DNA
<213> Homo sapien

<400> 4349
 agcgggcgaa tctttttcat tgaatttgaa ccatttgtaa aatctgtgat 50

 gctgaagcag agtgtgtcac aaagtgatga gaacattact aaaatccacg 100

 gacgcactgc gacctaaggg ctcaacggct gactcggcag cgggcagcca 150

 ccccacgctc ccctgcggtc actcgcacac cacagcctga agctccccca 200

 gcgcctgcac ctcgcacaca gctaaggtca aagttcaaac gcactccaca 250

 cggaagctca ttctataccc gaagagcagt ctcagaaagc aagattactt 300

 ttgtgttttt taaaaaatga ttctttaatg tatttttcta aacattctga 350

 ttggaagtag tggattccta aatgattcca aagtcatctg taattcttct 400

 gtttttgttt tgttctgtct tttcttcatt ttggctttgg gtggggggag 450

 gggcaggtga cacaaaggat tttttttttt tttttttaat ttttggaatc 500

 ttttccaata acaagctaaa gatttgcact gaaatacaac ttgtatgcct 550

 tttgcatttt taaagcctgc ttcctggatt taagcagagt gatagtgttc 600

 aaagagccag ttcagcctgt aacatatttg aaaaagatat gtctgcactt 650

 tgaggtccct tttgaatgcc attcactaga cctctcaagc attttgtttc 700

 attgctacat ccaagcgcct cacaagtcca caatgcggga cagcatcaaa 750

 agctcaagac tttggaaaaa gcttgtgggc ttgcactggg ggagggaagg 800

 gaacaaaatt tgtgtacttc tttgtttaat ttagaaataa ggcatccaag 850

 agatgccatt attttctgtg tttcaattgt tgtgcctttg agttaaactg 900

 catttttgtc ttttggttga aatctgaaat gtactgtccc aatataaaac 950

 agtaattatt tgacctttgc actgtttgtc tggtcctttt cagtttgatt 1000

 gcatataaat gtggaacttg atagatctct atatttttaa tgcacttgtg 1050

 ataaactggc agcagggtta gacattactt tcaaagcttg aggtagaccg 1100

 agtcagcatg ctagacaggc ttctctctct aaccaaaact gtaatcttca 1150

 ggaccagcaa actcagccca aggcagctaa tccccccaac cccatcctcc 1200

 gcgccccgtg cggctgatcg gcagccctga ttcgccaatt tgtcctctct 1250

 cattcactga tccaccagcc tgactgctaa gagctatagt ctttttagtt 1300

 gttttgtctt tttaagcaag atgaaaacct ttctattagg gattttgggg 1350

 ttgggagggg atgggcagag atataaaccc cagcctttaa gactttgaca 1400

 attgtacgta aatacagatg tgtataaata taggcacatg catattttta 1450

 tgtgaaagtt gattttaaaa aactaaaaaa atctaaactg cactcttatt 1500

 gataccatca taacgcaagt gggaaaaata agagtacgca gtctaattta 1550

 atttcatgca gtgggaaaat atatatgtgt gcttctgtaa catcctgaaa 1600

 acatagcttt ccatcccctg ttggctttga atggtgggcc gagcacccag 1650

 gtcgtctgta ttttggtttt cttttgctaa gcagagatct tgaattcttc 1700

 aaggtgctga tagcaactgc tggctccttt ctgtagtcac acacctaatg 1750

 ctagtttagt gattcaaaat gcatcacatt tttaggcagg acctagattt 1800

 tccctgtcaa cctaagatga aaataatttc agtgttgatt cagaactgaa 1850

 cattaagtag gccctcgtcc tgcagttggc cacttgagtg ttttgttttg 1900

 tttttatttt ttaaggtggg cattttcctt taacctctac tttttcaaaa 1950

 gcaacaaagg ggcctcaacc tgagtttcct atgggcctct cttctgcatc 2000

 cccaaagcgg ccaagagcaa atcctggggg ataagaaaaa agtgtaaact 2050

 aggtaggatt gtgatgctca aaataaccat ctagcaatat cttggagctt 2100

 gagaatagat tttgtgggct tatttcttct tgcctcttcc ccatcctttc 2150

 aagagagaac ttatttttga aaagtatcta tatatacaca cacacacaca 2200

 cacacacata ttattattta ggtttttata ccatactgta ttggcgagaa 2250

 taccactatc attgtccttt acagtctatt tcttccccca agtcttggtc 2300

 tttttttatt ttctattttt tcatgaacca cacaggagac tttaacatcc 2350

 tggtcttttc tgtttcttct ttgtttcccc aagtttgtct gtcccccttt 2400

 gccttccctg agtgttgaac atcaggtagt aaaaggctaa acgcaatttc 2450

 ttgcatgtca atctattctt tttctatgtt tgactctgat gcagtgtgtt 2500

 tagcgtgtct agtagctggc tactcctatt taaaaactct tcctggtaga 2550

 agacaaccca aagacccttt tcgatgaggt ggtttctcat tctacatcct 2600

 ctgatctcta tagactgtag gatgctttgc tttcaaagat aactgggtta 2650

 gagggtgggg tgtgcaatag gtgatttatc atggtttttt tcattatcaa 2700

 tattacatgg atgattttct cagattcttc tgaaagaaga aattgacagg 2750

 cactgctaga ttcagctatt gaatggctga agagattgag tatttgacct 2800

 tctctcaaaa tcataaagtg agaattcata aggcacccaa tgttaagatt 2850

 tatccagatt tttacatttt gatttcttct ctctgtgggg tggcaagttg 2900

 agggagcatt cttcatttta gcttttacct gacaaccaaa cttgccttta 2950

 ccccatccct agaattggtg ctcttggaat attgctgtta ccatcatttt 3000

 tggggggcca tcttcctaat gctacacaca gcctgacagg ggagcagcag 3050

 atgaaagggt atgctattct gtttccagat gtttctttat gtaaatatga 3100

 cgccaatgta aatcctgtgt caagatcata gagaatggtg ctttttacta 3150

 cagttagcac atgcattttt agaaactact acatgtttta gagaatcttt 3200

 gctgtgtata tgtaaactgt attgttcaac tgttaacaaa taataaatta 3250

 tttcattatt aaagaaaaaa aaaaaaaaaa 3280

<210> 4350
<211> 1878
<212> DNA
<213> Homo sapien

<400> 4350
 tctggcggat gaaaataacc agaatgaaaa tagctagaaa actcagcaag 50

 caggaagctc cctttctcac ccttttgttc ccttgccgat agaatcagtc 100

 actattagaa aaaatgaaag acgctctgtt taaaacaatg atgacagcag 150

 tacttaatat gtatttcgag gtgaacttat atagattgag agaggctgca 200

 tttggcagac tgatgtatag gaagacccat ttgtttctag cttctccctg 250

 cagggaaaat gctttcgtca ttatagcctc tttacacaga ctggccattc 300

 tagtgaaaca ggtggtaaac ctttgggctg cccagaaaca ttttatctgt 350

 tttcacttac ctaggaaggg gtaagattag cgggtcatcc aaaatctgta 400

 tgtaagctat cttcattttc ttccccaacc ttctcctcct gggaaacaca 450

 aatgctatct catctgacaa aaggttttag aggataaagc tgaaaagatt 500

 ggattgggat ctttttgtgg cttggggcgg agccttttgc taaaatctca 550

 agaatgctgc tttgagttta gctagggtgg ctctcagaac tggggtgcct 600

 ggcattctca gcatttctca ggggcctccc acctctgaca actgcagtgt 650

 tagctaatac ataccttgag catagaactg aatgctgtaa ttcagagcca 700

 tttttttttt caacttgaac attgtacaat tttactgcaa tttcctttga 750

 actttcttgc cactgtttgg aatcttaaaa attcattagc cttctccttt 800

 ctgacataaa gctactcttc atcagagatg agttcctatg tatgtccttt 850

 gttccttcaa tagctaatta atgtgcttga ggatacttca gtggaaaaaa 900

 aggtttaaat atgcaaatta ctaataaatg tgtaacctta tgtaacttgt 950

 gttacatcaa gtaacaagct aatctagttt gtttcactgg actaggcttg 1000

 tgctccctac ttcagtattt tgatgctttc cttgatcttt gtttcacaaa 1050

 atgttgtgaa ttttggtatc attcaaaaca aatgacattt attaggtttc 1100

 attttgaaac gatgtacaga caagtcccca acttagaaac cggtttgttc 1150

 ttaaggttct tgcgtcagcc catagaagcc cactgacctc caccacagcc 1200

 caaatggagg gctgtgatag ccagatctgg ttggcttttg tgggctgacc 1250

 cagacattta atcaccatct cttatgttgt tgccgtaaga aatgcattcc 1300

 aggttgggac ttgggatcct gagagcacat tcgccccctg tggtggccgc 1350

 ttgccacctt gcaagatgga agcccagtct ccttactacc aaactgtagt 1400

 tgtaagcaga gggaggggtg agatgtttat aggacattcc ctaagctggg 1450

 gagtgatttt tatcactatt catgtcaact gtactttggt atagactccc 1500

 tatcaattta ataatatgaa aagcctaaaa taaaactatg catgctattc 1550

 tatgtgctat tttatatcag taaataagct tatgcttgcc agttgtatac 1600

 acagttatga ggtgtataga actgactttg acagtatttt ttgcactgtt 1650

 tcctatctgt ttttataaag tcttatttag atattggacc ttgttgatgt 1700

 tctcactgcc cttgtgcttg ctataaaatg tttcatatgt gcctttacaa 1750

 atgtgagatc tttattctaa cctttttttg taaaagatat ctattgattt 1800

 ccaataatgt tcatcacagc atgtgcaata tgccaagatt accctcggtc 1850

 attcctgtca acaaggggtc aatgtcat 1878

<210> 4351
<211> 50
<212> PRT
<213> Homo sapien

<400> 4351
 Met Phe His Met Cys Leu Tyr Lys Cys Glu Ile Phe Ile Leu Thr
   1               5                  10                  15

 Phe Phe Cys Lys Arg Tyr Leu Leu Ile Ser Asn Asn Val His His
                  20                  25                  30

 Ser Met Cys Asn Met Pro Arg Leu Pro Ser Val Ile Pro Val Asn
                  35                  40                  45

 Lys Gly Ser Met Ser
                  50

<210> 4352
<211> 1088
<212> DNA
<213> Homo sapien

<400> 4352
 ggaattcggc acgagcccga ttccgcgccc gccatggccg acaaaatgga 50

 catgtctctg gacgacatca ttaaactgaa ccggagccag cgaggcggcc 100

 ggggcggggg ccgcggccgg gccggctcca gggccggccg ccgcggtggg 150

 gcgcaggccg ccgcgcgagt gaatcgaggc ggcgggccca tccggaaccg 200

 gccggccatc gcccgcggcg cggccggcgg aggcggcagg aaccgaccgg 250

 cgccctacag caggccaaaa caacttcccg acaagtggca gcacgatctt 300

 ttcgacagtg gcttcggcgg tggtgccggc gtggagacag gtgggaaact 350

 gctggtgtcc aatctggatt ttggagtctc agacgccgat attcaggaac 400

 tctttgctga atttggaacg ctgaagaagg cggctgtgca ctatgatcgc 450

 tctggtcgca gcttaggaac agcaaacgtg cactttgagc ggaaggcaga 500

 tgccctgaag gccatgaagc agtacaacgg cttccctctg gatggccgcc 550

 ccatgaacat tcagcttgtc acgtcacaga ttgacgcaca gcggaggcct 600

 gcacagagcg taaacagagg tggcatgact agaaaccgtg gcgctggagg 650

 ttttggtggt ggtggaggca cccggagagg cacccgcgga ggcgcccgtg 700

 gaagaggcag aggtgccggc aggaattcaa agcagcagct ttcggcagag 750

 gagctggatg cccagctgga cgcctataat gcgagaatgg acaccagtta 800

 aacagaccag caaatccgcg tgcggaacag gacccaggcg tctcctcttg 850

 ctccctggtt ggggggcggt ggctggggct gtgcgcccaa tgatggattt 900

 gtttctttta tgttttaaaa taggatttaa aaactcatgt aaaggttttt 950

 tttttttctt tttttttttt ttaattctga aacagacctg ttttgtaccg 1000

 agttattttt gggataaatt ttactggttg ctgttgtgga gaaggtggcg 1050

 tttccacctt ttccataata aaatagaaat gtgtgtaa 1088

<210> 4353
<211> 255
<212> PRT
<213> Homo sapien

<400> 4353
 Met Ala Asp Lys Met Asp Met Ser Leu Asp Asp Ile Ile Lys Leu
   1               5                  10                  15

 Asn Arg Ser Gln Arg Gly Gly Arg Gly Gly Gly Arg Gly Arg Ala
                  20                  25                  30

 Gly Ser Arg Ala Gly Arg Arg Gly Gly Ala Gln Ala Ala Ala Arg
                  35                  40                  45

 Val Asn Arg Gly Gly Gly Pro Ile Arg Asn Arg Pro Ala Ile Ala
                  50                  55                  60

 Arg Gly Ala Ala Gly Gly Gly Gly Arg Asn Arg Pro Ala Pro Tyr
                  65                  70                  75

 Ser Arg Pro Lys Gln Leu Pro Asp Lys Trp Gln His Asp Leu Phe
                  80                  85                  90

 Asp Ser Gly Phe Gly Gly Gly Ala Gly Val Glu Thr Gly Gly Lys
                  95                 100                 105

 Leu Leu Val Ser Asn Leu Asp Phe Gly Val Ser Asp Ala Asp Ile
                 110                 115                 120

 Gln Glu Leu Phe Ala Glu Phe Gly Thr Leu Lys Lys Ala Ala Val
                 125                 130                 135

 His Tyr Asp Arg Ser Gly Arg Ser Leu Gly Thr Ala Asn Val His
                 140                 145                 150

 Phe Glu Arg Lys Ala Asp Ala Leu Lys Ala Met Lys Gln Tyr Asn
                 155                 160                 165

 Gly Phe Pro Leu Asp Gly Arg Pro Met Asn Ile Gln Leu Val Thr
                 170                 175                 180

 Ser Gln Ile Asp Ala Gln Arg Arg Pro Ala Gln Ser Val Asn Arg
                 185                 190                 195

 Gly Gly Met Thr Arg Asn Arg Gly Ala Gly Gly Phe Gly Gly Gly
                 200                 205                 210

 Gly Gly Thr Arg Arg Gly Thr Arg Gly Gly Ala Arg Gly Arg Gly
                 215                 220                 225

 Arg Gly Ala Gly Arg Asn Ser Lys Gln Gln Leu Ser Ala Glu Glu
                 230                 235                 240

 Leu Asp Ala Gln Leu Asp Ala Tyr Asn Ala Arg Met Asp Thr Ser
                 245                 250                 255

<210> 4354
<211> 1088
<212> DNA
<213> Homo sapien

<400> 4354
 ggaattcggc acgagcccga ttccgcgccc gccatggccg acaaaatgga 50

 catgtctctg gacgacatca ttaaactgaa ccggagccag cgaggcggcc 100

 ggggcggggg ccgcggccgg gccggctcca gggccggccg ccgcggtggg 150

 gcgcaggccg ccgcgcgagt gaatcgaggc ggcgggccca tccggaaccg 200

 gccggccatc gcccgcggcg cggccggcgg aggcggcagg aaccgaccgg 250

 cgccctacag caggccaaaa caacttcccg acaagtggca gcacgatctt 300

 ttcgacagtg gcttcggcgg tggtgccggc gtggagacag gtgggaaact 350

 gctggtgtcc aatctggatt ttggagtctc agacgccgat attcaggaac 400

 tctttgctga atttggaacg ctgaagaagg cggctgtgca ctatgatcgc 450

 tctggtcgca gcttaggaac agcaaacgtg cactttgagc ggaaggcaga 500

 tgccctgaag gccatgaagc agtacaacgg cttccctctg gatggccgcc 550

 ccatgaacat tcagcttgtc acgtcacaga ttgacgcaca gcggaggcct 600

 gcacagagcg taaacagagg tggcatgact agaaaccgtg gcgctggagg 650

 ttttggtggt ggtggaggca cccggagagg cacccgcgga ggcgcccgtg 700

 gaagaggcag aggtgccggc aggaattcaa agcagcagct ttcggcagag 750

 gagctggatg cccagctgga cgcctataat gcgagaatgg acaccagtta 800

 aacagaccag caaatccgcg tgcggaacag gacccaggcg tctcctcttg 850

 ctccctggtt ggggggcggt ggctggggct gtgcgcccaa tgatggattt 900

 gtttctttta tgttttaaaa taggatttaa aaactcatgt aaaggttttt 950

 tttttttctt tttttttttt ttaattctga aacagacctg ttttgtaccg 1000

 agttattttt gggataaatt ttactggttg ctgttgtgga gaaggtggcg 1050

 tttccacctt ttccataata aaatagaaat gtgtgtaa 1088

<210> 4355
<211> 255
<212> PRT
<213> Homo sapien

<400> 4355
 Met Ala Asp Lys Met Asp Met Ser Leu Asp Asp Ile Ile Lys Leu
   1               5                  10                  15

 Asn Arg Ser Gln Arg Gly Gly Arg Gly Gly Gly Arg Gly Arg Ala
                  20                  25                  30

 Gly Ser Arg Ala Gly Arg Arg Gly Gly Ala Gln Ala Ala Ala Arg
                  35                  40                  45

 Val Asn Arg Gly Gly Gly Pro Ile Arg Asn Arg Pro Ala Ile Ala
                  50                  55                  60

 Arg Gly Ala Ala Gly Gly Gly Gly Arg Asn Arg Pro Ala Pro Tyr
                  65                  70                  75

 Ser Arg Pro Lys Gln Leu Pro Asp Lys Trp Gln His Asp Leu Phe
                  80                  85                  90

 Asp Ser Gly Phe Gly Gly Gly Ala Gly Val Glu Thr Gly Gly Lys
                  95                 100                 105

 Leu Leu Val Ser Asn Leu Asp Phe Gly Val Ser Asp Ala Asp Ile
                 110                 115                 120

 Gln Glu Leu Phe Ala Glu Phe Gly Thr Leu Lys Lys Ala Ala Val
                 125                 130                 135

 His Tyr Asp Arg Ser Gly Arg Ser Leu Gly Thr Ala Asn Val His
                 140                 145                 150

 Phe Glu Arg Lys Ala Asp Ala Leu Lys Ala Met Lys Gln Tyr Asn
                 155                 160                 165

 Gly Phe Pro Leu Asp Gly Arg Pro Met Asn Ile Gln Leu Val Thr
                 170                 175                 180

 Ser Gln Ile Asp Ala Gln Arg Arg Pro Ala Gln Ser Val Asn Arg
                 185                 190                 195

 Gly Gly Met Thr Arg Asn Arg Gly Ala Gly Gly Phe Gly Gly Gly
                 200                 205                 210

 Gly Gly Thr Arg Arg Gly Thr Arg Gly Gly Ala Arg Gly Arg Gly
                 215                 220                 225

 Arg Gly Ala Gly Arg Asn Ser Lys Gln Gln Leu Ser Ala Glu Glu
                 230                 235                 240

 Leu Asp Ala Gln Leu Asp Ala Tyr Asn Ala Arg Met Asp Thr Ser
                 245                 250                 255

<210> 4356
<211> 2578
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 747-895
<223> Unknown base

<400> 4356
 aaaaaatatt ttccctatta gagaagagat tgtggtttca ttctgtattt 50

 tgtttttgtc ttaaaaagtg gaaaaatagc ctgcctcttc tctactctag 100

 ggaaaaacca gcgtgtgact actcccccag gtggttatgg agagggtgtc 150

 cggtccctgt cccagtgccg agaaggaagc ctcccacgac tgcccggcag 200

 ggtcctagaa attccccacc ctgaaagccc tgagctttct gctatcaaag 250

 aggttttaaa aaaatcccat ttaaaaaaaa tcccttacct cggtgccttc 300

 ctctttttat ttagttcctt gagttgattc agctctgcaa gaattgaagc 350

 aggactaaat gtctagttgt aacaccatga ttaaccactt cagctgactt 400

 ttctgtccga gctttgaaaa ttcagtggtg ttagtggtta cccagttagc 450

 tctcaagtta tcagggtatt ccagagtggg gatatgattt aaatcagccg 500

 tgtaaccatg gacccaaaat ttaccagacc acaaaacttt tctaatactc 550

 taccctctta gaaaaaccac caccatcacc agacaggtgc gaaaggatga 600

 aagtgaccat gttttgttta cggttttcca ggtttaagct gttactgtct 650

 tcagtaagcc gtgattttca ttgctgggct tgtctgtaga ttttagaccc 700

 tattgctgct tgaggcaact catcttaggt tggcaaaaag gcaggannnn 750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnggcag 900

 gcaggcggtt atggtggttc cctcccatcc caccacataa agtttctgag 950

 acttgagaac agcaaaatgc tgttaaaggg aaatattaag aatgagaatc 1000

 tgcagtaagg gtgattctgt gcccacagtt cttcaattct ttataccgtt 1050

 ttacccacat gtggtgttac caaagccggg cagaaccatg ctagcggaag 1100

 atgtgaaatc cagatagctc attattgcca agagctaggc agctttgatc 1150

 tccaaattgt tattgctttc atttttattg taatggaatt gctttgtttt 1200

 gtttttttgt ttttgtattg aagagggttg ttttcccttt atttttcata 1250

 agctaatgta aatgaagaaa aaatgtcttc tctgggctgt aggcctggct 1300

 cagcgtacac aggtatacat cctaagctct ctatgttctc taatctgtgg 1350

 tgactgaaca tgtgtctcaa tgcacggggc atttctacct gtgtttctgc 1400

 agcaccccca ctgccttgag tccccagcag tgctgttatt tgcctaacac 1450

 ctgtagccat ctgccacgca gccagacgtg aaacgctgag acagagacca 1500

 tttaggttaa atacgacagc ttatcctgct gggtggggaa agtaaaaaat 1550

 atgctggttc aaggcctaaa gtaaaatgat caataatgtt tgtagcatta 1600

 atgaaatatt ttcaagaaat gtgtccaggg gtagcactgg ctatgttgac 1650

 gaggcctttg gtaactcaga gagctcttgg ccctgatggg gacttgccct 1700

 tacgctttct ttatcaggct ctgagttcac acggagcctc tggcacttcc 1750

 ctgctgtctt gggagaaagg aaactggttg ccgcggcagg ttgtggaatc 1800

 tgttgctgga accaggctgg aagcccacct ggtagtgaac agggcccagt 1850

 ggggcaggct gggcatgttg tggtctatgg gtttgtttcc tggagaatgt 1900

 tcaggaatgt cttcccagct gctttggtgc tgagctctat tatctcacag 1950

 cacgtccaga aggctaaccc aggtggggag gatgctgaca ccagctccag 2000

 gtggagttgg tggtcttaat ttggagatgc aggggcaacc tgtgaccctt 2050

 tgaggcaaga gccctgcacc cagctgtccc gtgcagccgt gggcaggggc 2100

 tgcacacgga ggggcaggcg ggccagttca gggtccgtgc caggccctcc 2150

 tcagtgccct gtgaaggcct cctgtcctcc gtgcggctgg gcaccagcac 2200

 cagggagttt ctatggcaac cttagtgatt attaaggaac actgtcagtt 2250

 ttatgaacat atgctcaaat gaaattctac tttaggagga aaggattgga 2300

 acagcatgtc acaaggctgt taattaacag agagacctta ttggatggag 2350

 atcacatctg ttaaatagaa tacctcaact ctacgttgtt ttcttggaga 2400

 taaataatag tttcaagttt ttgtttgttt gttttaccta attacctgaa 2450

 agcaaatacc aaaggctgat gtctgtatat ggggcaaagg gtcagtatat 2500

 ttttcagtgt tttttttcta ccagctattt tgcatttaaa gtgaacattg 2550

 tgtttggaat aaatactctt aaaaaata 2578

<210> 4357
<211> 110
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 747-895
<223> Unknown amino acid

<400> 4357
 Met Lys Tyr Phe Gln Glu Met Cys Pro Gly Val Ala Leu Ala Met
   1               5                  10                  15

 Leu Thr Arg Pro Leu Val Thr Gln Arg Ala Leu Gly Pro Asp Gly
                  20                  25                  30

 Asp Leu Pro Leu Arg Phe Leu Tyr Gln Ala Leu Ser Ser His Gly
                  35                  40                  45

 Ala Ser Gly Thr Ser Leu Leu Ser Trp Glu Lys Gly Asn Trp Leu
                  50                  55                  60

 Pro Arg Gln Val Val Glu Ser Val Ala Gly Thr Arg Leu Glu Ala
                  65                  70                  75

 His Leu Val Val Asn Arg Ala Gln Trp Gly Arg Leu Gly Met Leu
                  80                  85                  90

 Trp Ser Met Gly Leu Phe Pro Gly Glu Cys Ser Gly Met Ser Ser
                  95                 100                 105

 Gln Leu Leu Trp Cys
                 110

<210> 4358
<211> 3156
<212> DNA
<213> Homo sapien

<400> 4358
 ccttcaaaga agaaataaga gaattattag taatttgctc agaatctggt 50

 atgtggaaga gccaacatgg ggacccagcc ttttgtgatt ctaaaacctt 100

 tgatctttct actaacattc actgttagag agtgtaggcg ctgcaggaga 150

 aagagaaagt gcccacgaaa attagtctag cattgccggg ggtaaaaagc 200

 acacactggt cctgcagctt attgaatcag agaaatgtga agataagatg 250

 aactaaacaa acatatttta gagcatggat ctcgaagcag aatttggcta 300

 aattttaaca aaatgttctt cagtaacaca tctcatgatc tgaagattgt 350

 gttacaaaaa atattatcag gccaaaattt gttcggaata cactaatttt 400

 tgctcctcta tatgtgagga aaatgagact agacagattt aagtaattga 450

 caacttactt aaagtagcaa agtcatggat tgtattgact tttaaaaata 500

 tagtaaaagt catatttaaa ctttatccta aagtttaaat ctaacagaac 550

 aactgaaata cttgaaatag acctataaaa tagtaattaa aatgagaaat 600

 acataagatg ataaataaaa tgaaggtgaa ggtattccag atctaccgaa 650

 aagattttca gtatcacaga ttattcataa gaaattgaga aaaggaacaa 700

 tcagaagttg caaaagatgg tatagccgaa tataatggaa ataggaaaaa 750

 ttagtcgaaa ataaaggttg atttagaaat gaagaaaatg aatatatttc 800

 ttaatacaaa ataagtggga aatgagaagt tataccaata aaaagcattt 850

 aaaaatttag gggatattgt aacccagtat aattttctga caggttggac 900

 tttgacccta atggacttac tggtgaactt tttcaaatgt ttaaataatg 950

 tctatccatg tatcatgaag gacagtatgc ttcaaattgt cttttgaggc 1000

 agacatgttc tcagtactaa aagacatttt tagaaggatt ttattctcaa 1050

 cagatgcaaa atgcaaaata aaatattgac aaacaataca gcaacaaata 1100

 atttactatc actcaggatt ataaggctgg tgttaagcag aacagccatt 1150

 aaatcagcat caaaagaaca aatagtaaaa tccaaagtat taattacaga 1200

 taacttttca aaaattcatc attcaccctt gatttaatta tttctctggc 1250

 aatgatttaa tagacttctc ggagtctgtt aagtacttaa accaagaact 1300

 accattattc ctactgggaa aacataaaca tttctcaagt ggaaagtaaa 1350

 cagtgttggc actattttta tatatggtta aagagacctg tcattgcaat 1400

 aaaagccagc attcacaaaa tgaggaagat aaggaaagta gcataaatat 1450

 tttctattaa catggcttta caactgctaa aacttatagt ataaaaatgt 1500

 actaacaaag actaattcaa gaagttgcag gatacacaat ttttaaaaat 1550

 ctcatttcta catcttagca gtgacaaact gcaatttaaa aagtgtgttt 1600

 ggttattaat atatatgaga cttttaaaga aagttatata actacataga 1650

 gataaattaa gaaagatgcc taaatagaag caagtttaaa gagctatatt 1700

 tttaaacatg aacaaactcc catgggagcc atgccagtgt agtggaaaag 1750

 tagtacatgg ggagatgggg agtttttttg aaaaccagaa ttacagttct 1800

 catttcacta cttaccagtt gtatactctt gggaaagtca ctcctagtat 1850

 ctatttcacc atctacagaa gagaaatact tcacagaatt attgtgggga 1900

 ttaagttaga taatgtgttt taaaatataa agctacatcc aaagaaatgc 1950

 caatatgtga cattagtatg aaatttacta cagttccatt taacattcca 2000

 actggttgct gtgtggaata tggcataatt gtaataaatt atttaggaaa 2050

 gcaagcaaag atgtaagttt ttttaattta gggggaaaaa atgggagcct 2100

 tgctctccaa atccttaaaa catgctatta agcaaccttt ctgaatattc 2150

 tgtggtgcca agtagaaagt ttaactgaaa ttaataagcc aatggaaaga 2200

 aagaaatatt aataactgct ggtggaaaga ctagctagat gtcagtgtgg 2250

 aaagattaga tccactttac atgtgatatt ccaaatgaat taaaatgtta 2300

 agtataaaaa gaaaaatact acaagtctca caccaatagt ggtataaagg 2350

 aacttcatgg caattggcaa ggtagatcaa ctaagagaaa aagttttaaa 2400

 tgtgtagtaa ataggaaaaa gacaaaacaa gatggaattt aaaagaagct 2450

 atttgcatta cacatggatg cactcagttt ttgtaaaact atatgcatat 2500

 ccataagggt ttgtactctt aggcaaattt ataaagcgat cgtgtataaa 2550

 tgatataaaa aatcaatttg aatggtattc aaatttccta atattaaaaa 2600

 tgcaactttg acttagttca tgctattgta ttagcaaaac tgttttaatt 2650

 gcatgtgtcc ttatagcagc agcattgtgt attagtagcc ttttaagaga 2700

 actgtgtaga agactataaa aagggcttta taactgatct tttgacatac 2750

 tcactttgag tggcatatgc ccaggaaaat atttaaaaga aagaaaagct 2800

 atttgtacaa agttttctag cagttccact cagataactt taagggggaa 2850

 aaaagcccaa cgattggaaa tggttaagta aattttggtg tattgctagt 2900

 gctatcacag aatgttatat agccattcaa taatattgat atatgtcaaa 2950

 ttgtatgcaa aaaagtgaga ttcaaaaatg ttaataagaa cataaattgt 3000

 gtttactgat acatgtgaaa atttaggtct acattgaaaa gaatcagaag 3050

 ataacatgta attcagttta acattagggg ttctttattt ttcttctgtt 3100

 aaatattgat gtatgcaata aaaaataaaa gattaattgg taaaaaaaaa 3150

 gtcgac 3156

<210> 4359
<211> 71
<212> PRT
<213> Homo sapien

<400> 4359
 Met Asn Lys Leu Pro Trp Glu Pro Cys Gln Cys Ser Gly Lys Val
   1               5                  10                  15

 Val His Gly Glu Met Gly Ser Phe Phe Glu Asn Gln Asn Tyr Ser
                  20                  25                  30

 Ser His Phe Thr Thr Tyr Gln Leu Tyr Thr Leu Gly Lys Val Thr
                  35                  40                  45

 Pro Ser Ile Tyr Phe Thr Ile Tyr Arg Arg Glu Ile Leu His Arg
                  50                  55                  60

 Ile Ile Val Gly Ile Lys Leu Asp Asn Val Phe
                  65                  70

<210> 4360
<211> 4282
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4057
<223> Unknown base

<400> 4360
 tgacaaaatc ttttatttat ttaaatgtta gtaatacgtt tattgatgag 50

 actaggagct tctctgcagc atcttcataa tacattggtt ttagttccca 100

 cactattccc acatcttatc tgggaagatt agaaatacag atgtaatatg 150

 gaagcttcaa cagcatgggg gtggtgatag tgtcctattt gcccttggta 200

 aaatattaaa gcgtatttct taacccaaag agtgattggt tatatgaata 250

 tatttgaaaa agttaaagca aatttgcaaa cctttacaaa atcatgtatc 300

 aattttatgc tatccagttt ttacgtaccc atgtgtcaac atttcatata 350

 tccagttctt tgggtgctgg ttcacttttt ttcatttatt caaattcaga 400

 aaaatacgga cggatctaat gttaaattaa ccagaaaccc tggaacattc 450

 atatcttgag agggaatttg ctactctttt acttttggga tttcattata 500

 aaataggctc attttataca tatgtcctgt ggtctgtctt ccagagtgtg 550

 ctgtaatcat aagtctctag caaagagtgg agggtggagg gtgtgtagaa 600

 ctccactcag cctcatggat acatctacaa gtctctcaac ccatcctgtt 650

 acagttctcc atgagagtca cctcacactt ggaaaagaag gaggttaaag 700

 cagagtattg ttggcagcca gctatgccca tcctcttgta aataactttc 750

 caacacaccc atttccttgc cttaaggtgc aggttcctac ttctacaaaa 800

 tttcaaatga ttgcaggtca aaaacctttg gagttactca caaataataa 850

 taaaatttca aataactagg gtctacttgt ccatcaagat gacattacca 900

 gtggaaccca cctgttaatt ttaaagtagc ttcagaaccc aacaaaaatt 950

 atgtaagcct ggttaaatgt ccttttttct tcttgcctct aataaaatca 1000

 ggatcttcgg ccttgatact aaatatgtgt atatttagtt atgatggtac 1050

 ttgtagatgc tcacatttcc agttccaaac tcgcccgtac tttttatgtg 1100

 cttcaaaata ttggacacat ttctgttaat atatgatttc tgtatccaca 1150

 aaccgctgtt tgcttatgct gagtcaattt agaagttaat ttccaatcta 1200

 gtctcaactg caatgcattt aaaataggta aaacaagtaa atgagtttgg 1250

 gacattttga gattaatgtt actgcccact tgactgtcaa tttcaaatgg 1300

 ctcctaatgc aaccaaaatt ataaccaatg tagcatgtgt aggaaaggta 1350

 tttttaatta tttaaaatca ttgtgtatat tacagcagta tgaggaatgc 1400

 ctggctaaag aggatttttt aaaagatgaa gaatggtttt gcttgtatta 1450

 tataggctta ctgagtttgt gagcagcata aaaacaatca ttccttaatt 1500

 cttcattgtg gaactgaaat atttctgtaa tgcatttttt aaaaggagac 1550

 tcctagacac agctgtaata gtgggaatag aaatgtagag cttttctcat 1600

 aacacaaaac cagaaaataa ttttcagcac tttgacttac tctatgtaat 1650

 aaggaaaaaa attgtttcca caaagttgaa ctatgtagta atatttggta 1700

 acatatggca tggccacttt atatcacaga atgtgtgtca agttgcaaag 1750

 catacttggg ccatagcaga cactaagaat taaaactctt aaatcagtga 1800

 aacaaaaact aatgggcagc attctctctg tttggaatgg gatcagtata 1850

 caattaatac aatttaattt tacacattcc ctaagacacc atttttaagt 1900

 tacagtcaca tgagtgtttg tataaattta agtcaatgct tttagcctag 1950

 gcaaagctaa atacaaggtt tttggggttt tcttttttca gctttattat 2000

 tgaagtatta caaacttaac atcagatacc aatgtgtaaa aagtactatt 2050

 gggtccttaa gggctctatc agggagttga aatttcatac gctttaccag 2100

 gttacttgta aaaaatgaac agctgtaaga catttcaaaa ccattgcaga 2150

 cacattgtta aaatgcagcc atttgataat gaaagcagaa accttaagtt 2200

 ttacctaatt attgcactaa atgtaaatga taacataaaa ttaagtgtgc 2250

 attttaaaca gattctattt cccacttact gcttagcata gaaaaagagc 2300

 tatggttaga ggagtgacca gcaagattta tttcagatgg aaaaggggtg 2350

 agaaagtgga agcaccttac tgttagagca tgttgcatct atttagtgct 2400

 actgaacaat tcagtagtta tttctgaact ttgctgcaaa gtgctcttta 2450

 gttaaagcac attaagaagg gtcactgctt aattgctttg taaaatgaag 2500

 caatggtatt ttttatccga tatagtgtaa tttaaaagtt ttcctacaaa 2550

 gtgagtttat attgttgcct aaactatgtt atgtaagcaa aggttttgga 2600

 aaggcgggag ggagtctaga ttcggcgaga gtgtgcgttt gtgtgtgtga 2650

 atgtatgaaa agtttcccca ttgggttatt cttaagatgt gtttattgta 2700

 aagttttcta cgttttgccc acagtaaatg tacaacttcg caattgtagg 2750

 atttaattga ttgaattcca aatttatact gtctcttccc ttctgcagag 2800

 acattatgcc actgtaaggt gcatgtacag aaaatacctc tgaggttgac 2850

 ttgttaaata actgatgaat gttatttcac actgaatctc aaagcagtca 2900

 tttgttttgc gggttagggg aaagttttgt tttttgctgg tgttttttgt 2950

 tgtttttaat taggcacact aagagtggct aaatttgggg gaattggtgg 3000

 ataggaaaga ccttgaaaag tgatgtgtag atgaaaacac aaggtatgga 3050

 tgttggttac agagttcagt tttaacaagg gaaatttggg gatttttttt 3100

 tttttacttg catgttctat gggtagctat caaagggtgt aacaaattat 3150

 tccagctttt cccaatacta attatattgg ttttaaaaag tctgcataat 3200

 cactaggtgg cattttccct tcatttgtga accaagaggg gtaaatgatg 3250

 ctacccatac agtgacttct gagttcttta actttgacag aatctccatt 3300

 gtttcattga atttctcatt gtattatatg tctttccaag tgtgcaaact 3350

 ataatatgta gttaatgaaa aatggaaggc tgcagattat tttgcatgaa 3400

 taattaattg cccattaggg ctaaggagac tgacatgatt tttatcggtt 3450

 ctgggtaaat gaaaatttta atggaaaact cattcaccat ttactagctt 3500

 tgtgcaatat tataaaaggt agaagcaaaa cactagcaca ttgtgctttg 3550

 cttggcttgt aaggatggct ttagtaccat tacattaaat ggacagtgtg 3600

 cacagtgtat tgtaaatgcc aactcttgca aatttacaat acttaaatat 3650

 gttcaattaa catcctaaag tattaaaagt acagaggaaa aactaagcaa 3700

 gcatttatag caataccatg aaatctccag taatcgtttt gactgttgcc 3750

 ttttgctctt tagtgcagct tttctgcatt gtaattgtat tgctttgtat 3800

 ttcatgtttt ttacactcat gacttcagag ttaagtactt gtacaccaag 3850

 tattgcaatc acctttctct tgttgtacat gcaatgtaac aacctacagt 3900

 tttggtgctt ttaacaatat tcctcttttt ctttaataaa ggatatttat 3950

 ttgaattaac ctgattttgt ttgtttaaaa tatcagtggt acatattttc 4000

 acttcatttc aaataggagg accatagcaa attgtatatc tgttatgaca 4050

 aaagttntaa catggagaac aggatccaga gaccatccat gcctgtattt 4100

 ctgcctcttc ctgagcgctg tttgttgtga catattttga tggcaacttt 4150

 ctttgtgcta ttaatgaact ttctcattgt ttataaatat tcacaaagtt 4200

 tggaagtgct gacttccaaa ttggaaaatt tttaaatggg ggtggggaga 4250

 ggcagaaaaa tatttataaa gttacacact ca 4282

<210> 4361
<211> 25
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4057
<223> Unknown amino acid

<400> 4361
 Thr Lys Ser Phe Ile Tyr Leu Asn Val Ser Asn Thr Phe Ile Asp
   1               5                  10                  15

 Glu Thr Arg Ser Phe Ser Ala Ala Ser Ser
                  20                  25

<210> 4362
<211> 2012
<212> DNA
<213> Homo sapien

<400> 4362
 gcggctgtcc agtcgtagcc cggccgcccg cgcctgtccg gtccggtccg 50

 gccacggagg cagcgcagcg gcgggactcc gagcctaccc cgccgagtga 100

 gctgcgccgc accgtgccgt cccacccggc acccaccagt ccgatggggc 150

 cgcagcggcg gctgtcccct gccggggccg ccctactctg gggcttcctg 200

 ctccagctga cagccgctca ggaagcaatc ttgcatgcgt ctggaaatgg 250

 cacaaccaag gactactgca tgctttataa cccttattgg acagctcttc 300

 caagtaccct agaaaatgca acttccatta gtttgatgaa tctgacttcc 350

 acaccactat gcaacctttc tgatattcct cctgttggca taaagagcaa 400

 agcagttgtg gttccatggg gaagctgcca ttttcttgaa aaagccagaa 450

 ttgcacagaa aggaggtgct gaagcaatgt tagttgtcaa taacagtgtc 500

 ctatttcctc cctcaggtaa cagatctgaa tttcctgatg tgaaaatact 550

 gattgcattt ataagctaca aagactttag agatatgaac cagactctag 600

 gagataacat tactgtgaaa atgtattctc catcgtggcc taactttgat 650

 tatactatgg tggttatttt tgtaattgcg gtgttcactg tggcattagg 700

 tggatactgg agtggactag ttgaattgga aaacttgaaa gcagtgacaa 750

 ctgaagatag agaaatgagg aaaaagaagg aagaatattt aacttttagt 800

 cctcttacag ttgtaatatt tgtggtcatc tgctgtgtta tgatggtctt 850

 actttatttc ttctacaaat ggttggttta tgttatgata gcaattttct 900

 gcatagcatc agcaatgagt ctgtacaact gtcttgctgc actaattcat 950

 aagataccat atggacaatg cacgattgca tgtcgtggca aaaacatgga 1000

 agtgagactt atttttctct ctggactgtg catagcagta gctgttgttt 1050

 gggctgtgtt tcgaaatgaa gacaggtggg cttggatttt acaggatatc 1100

 ttggggattg ctttctgtct gaatttaatt aaaacactga agttgcccaa 1150

 cttcaagtca tgtgtgatac ttctaggcct tctcctcctc tatgatgtat 1200

 tttttgtttt cataacacca ttcatcacaa agaatggtga gagtatcatg 1250

 gttgaactcg cagctggacc ttttggaaat aatgaaaagt tgccagtagt 1300

 catcagagta ccaaaactga tctatttctc agtaatgagt gtgtgcctca 1350

 tgcctgtttc aatattgggt tttggagaca ttattgtacc aggcctgttg 1400

 attgcatact gtagaagatt tgatgttcag actggttctt cttacatata 1450

 ctatgtttcg tctacagttg cctatgctat tggcatgata cttacatttg 1500

 ttgttctggt gctgatgaaa aaggggcaac ctgctctcct ctatttagta 1550

 ccttgcacac ttattactgc ctcagttgtt gcctggagac gtaaggaaat 1600

 gaaaaagttc tggaaaggta acagctatca gatgatggac catttggatt 1650

 gtgcaacaaa tgaagaaaac cctgtgatat ctggtgaaca gattgtccag 1700

 caataatatt atgtggaact gctataatgt gtcattgatt ttctacaaat 1750

 agacttcgac tttttaaatt gacttttgaa ttgacaatct gaaagagtct 1800

 tcaatgatat gcttgcaaaa atatattttt atgagctggt actgacagtt 1850

 acatcataaa taactaaaac gctttgcttt taatgttaaa gttgtgcctt 1900

 cacattaaat aaaacatatg gtctgtgtaa aaaaaaaaaa aaaaaaaaaa 1950

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2000

 aaaaaaaaaa aa 2012

<210> 4363
<211> 520
<212> PRT
<213> Homo sapien

<400> 4363
 Met Gly Pro Gln Arg Arg Leu Ser Pro Ala Gly Ala Ala Leu Leu
   1               5                  10                  15

 Trp Gly Phe Leu Leu Gln Leu Thr Ala Ala Gln Glu Ala Ile Leu
                  20                  25                  30

 His Ala Ser Gly Asn Gly Thr Thr Lys Asp Tyr Cys Met Leu Tyr
                  35                  40                  45

 Asn Pro Tyr Trp Thr Ala Leu Pro Ser Thr Leu Glu Asn Ala Thr
                  50                  55                  60

 Ser Ile Ser Leu Met Asn Leu Thr Ser Thr Pro Leu Cys Asn Leu
                  65                  70                  75

 Ser Asp Ile Pro Pro Val Gly Ile Lys Ser Lys Ala Val Val Val
                  80                  85                  90

 Pro Trp Gly Ser Cys His Phe Leu Glu Lys Ala Arg Ile Ala Gln
                  95                 100                 105

 Lys Gly Gly Ala Glu Ala Met Leu Val Val Asn Asn Ser Val Leu
                 110                 115                 120

 Phe Pro Pro Ser Gly Asn Arg Ser Glu Phe Pro Asp Val Lys Ile
                 125                 130                 135

 Leu Ile Ala Phe Ile Ser Tyr Lys Asp Phe Arg Asp Met Asn Gln
                 140                 145                 150

 Thr Leu Gly Asp Asn Ile Thr Val Lys Met Tyr Ser Pro Ser Trp
                 155                 160                 165

 Pro Asn Phe Asp Tyr Thr Met Val Val Ile Phe Val Ile Ala Val
                 170                 175                 180

 Phe Thr Val Ala Leu Gly Gly Tyr Trp Ser Gly Leu Val Glu Leu
                 185                 190                 195

 Glu Asn Leu Lys Ala Val Thr Thr Glu Asp Arg Glu Met Arg Lys
                 200                 205                 210

 Lys Lys Glu Glu Tyr Leu Thr Phe Ser Pro Leu Thr Val Val Ile
                 215                 220                 225

 Phe Val Val Ile Cys Cys Val Met Met Val Leu Leu Tyr Phe Phe
                 230                 235                 240

 Tyr Lys Trp Leu Val Tyr Val Met Ile Ala Ile Phe Cys Ile Ala
                 245                 250                 255

 Ser Ala Met Ser Leu Tyr Asn Cys Leu Ala Ala Leu Ile His Lys
                 260                 265                 270

 Ile Pro Tyr Gly Gln Cys Thr Ile Ala Cys Arg Gly Lys Asn Met
                 275                 280                 285

 Glu Val Arg Leu Ile Phe Leu Ser Gly Leu Cys Ile Ala Val Ala
                 290                 295                 300

 Val Val Trp Ala Val Phe Arg Asn Glu Asp Arg Trp Ala Trp Ile
                 305                 310                 315

 Leu Gln Asp Ile Leu Gly Ile Ala Phe Cys Leu Asn Leu Ile Lys
                 320                 325                 330

 Thr Leu Lys Leu Pro Asn Phe Lys Ser Cys Val Ile Leu Leu Gly
                 335                 340                 345

 Leu Leu Leu Leu Tyr Asp Val Phe Phe Val Phe Ile Thr Pro Phe
                 350                 355                 360

 Ile Thr Lys Asn Gly Glu Ser Ile Met Val Glu Leu Ala Ala Gly
                 365                 370                 375

 Pro Phe Gly Asn Asn Glu Lys Leu Pro Val Val Ile Arg Val Pro
                 380                 385                 390

 Lys Leu Ile Tyr Phe Ser Val Met Ser Val Cys Leu Met Pro Val
                 395                 400                 405

 Ser Ile Leu Gly Phe Gly Asp Ile Ile Val Pro Gly Leu Leu Ile
                 410                 415                 420

 Ala Tyr Cys Arg Arg Phe Asp Val Gln Thr Gly Ser Ser Tyr Ile
                 425                 430                 435

 Tyr Tyr Val Ser Ser Thr Val Ala Tyr Ala Ile Gly Met Ile Leu
                 440                 445                 450

 Thr Phe Val Val Leu Val Leu Met Lys Lys Gly Gln Pro Ala Leu
                 455                 460                 465

 Leu Tyr Leu Val Pro Cys Thr Leu Ile Thr Ala Ser Val Val Ala
                 470                 475                 480

 Trp Arg Arg Lys Glu Met Lys Lys Phe Trp Lys Gly Asn Ser Tyr
                 485                 490                 495

 Gln Met Met Asp His Leu Asp Cys Ala Thr Asn Glu Glu Asn Pro
                 500                 505                 510

 Val Ile Ser Gly Glu Gln Ile Val Gln Gln
                 515                 520

<210> 4364
<211> 3804
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 343-382, 1239-1264
<223> Unknown base

<400> 4364
 gctcatttgg gggcatgaat gttctcctta ctaacctctc atggagtcat 50

 gtgataacag ccatgtcatg tgtatggatg ccaccattct tgaatttctg 100

 ctagaaataa gtaggttgct atgcacttag agtcatcttt gcaagggact 150

 cattccaaac caattccaat cgacctgaaa gtcccttgca ctaaagaaat 200

 gtgatttttt tttaacccaa ggagaaagtt ggttgtaaca atttttcacc 250

 agaattagca atctgataga ataggctttt ttaacaggaa ttttaaactg 300

 gcggtgccag ttgcagtgaa ggtgaagtgg ctattgcttt atnnnnnnnn 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncctgaaga tagagcgttg 400

 aacaaaccca atggtcttgg ccctcaaaaa gctttatgtg acatagagca 450

 tccagctcga caattagcaa acccctgata ttattcatgg acttgacatg 500

 aggtttggac tattcatgag caacagcaga aggtccatga cccctacaaa 550

 tttacatttt tctatggccc atatttgaaa acctcacatt cggagcaggc 600

 cactttatat tcgtgagtga tcccaagctc actgaccaac agaaaagatg 650

 ctaaaaaaat gtgtcctatc atgtgcctgc tccaactgat gggtaatgtc 700

 tgcctttaag ccccagaatg gattctccag gcacagtgtg gaagagtgct 750

 gtggttgatt agcaatgtct gccttgggtg aggaaagggg aacactcctc 800

 aagtgcctcc tactgtcatc tccattcagc ctagcaccac atccccatgt 850

 agaagtgttg tcttctactg cttgccacgt acaagtgtga aatgccaagg 900

 tgagactcgt acacttgggg atttgcaatg gtttttaccc ctcatgaagg 950

 tcagaggtgg actatttgta cacatacaca catgcacacc ctctcacgtc 1000

 ctccagaggc tgaaagacca tcagcatctt ggtaactgcc atgcatgagc 1050

 agcaaggaca gccttccata atccatgccc catttcctct ggaagcctgg 1100

 aaacttttca tttcctgttc cttgctaatt aacatctaaa catgcttctc 1150

 atttccagcc attgctgatg cttctcagtt gaagtttgag ccacatccct 1200

 cttacagcta gtgaatgagt tggtagcaga tactgtatnn nnnnnnnnnn 1250

 nnnnnnnnnn nnnnagggga gggtgggatg gggtgtgggt aagttttgcc 1300

 ttttgttttg tttttgatgc cgtatatagt gaaggggtga ggatattcta 1350

 aacaaacaaa aattgaataa tttattcaca gaaactatta agattgtatt 1400

 gtaaagctca cagcaagctc agtgggcagc agctgcaaca tctcaccggg 1450

 gaaattattt tatttaacgt gagtgagatg tgggccggag aaggtagctg 1500

 aagctattta taaaacgttg tgtaccttct tccgagctct ctcccctttg 1550

 tgaagggcgc agcaactata cccttgatgg atggagattt atgcaatgtg 1600

 ttttactggg tagagtgaca gaccttggct gtccctggaa ttgagaatct 1650

 ggaccttatt tccaggcaga gaacactgtc ctcagaaatg ggacttctga 1700

 taatgaaaca ggttgtccaa cattttctaa tacgcattct acagaacaca 1750

 ggttccagga ggcatcaggt tggtgtgatg cagactaagg gttttgtggt 1800

 caaatatcct taagaaacaa agttaagtca gtttcctttc tgcaaggact 1850

 tttcagcctt caatgtgtgc tgtgcatggt gaatccccaa aaataatcct 1900

 tgagtctgta gcatttcctg aacttacatg accaggatac tctattttgc 1950

 agatcacccc acagagctag ggttccaccg agtatacttt gcttaggttg 2000

 acttagcata tctgaggtct tcaaggataa aaactgccac cccaacaccc 2050

 ttccattaaa aaaaaaaata caaaatagca ccacagtctc catctggttt 2100

 atagcaacag aggtacttta tttaatgaag caatggttct aatcctggat 2150

 actgccacgg actacaattc tatccctccc agagggagtg gaggaagtct 2200

 tgggtggtgt ggacagaagg aagagaggag agggtgagtg gggtataggg 2250

 cccagggtgg ctccctactc ctcaggctca aaaggatgct cagtgggaac 2300

 agatgatctc ttgatgagtg cttcttcagt ttcatagttt ggaatcgttc 2350

 actgtgtgct ttttgggggg ttttcaatgg aaattcacgt tgctttgcat 2400

 ttctgtgtcc gtctttggtc agttgtgcaa gcctgctcac tgtcatgtga 2450

 agatggcctt tcatctggct tctctctctt aagtgagaaa gattgtcctt 2500

 caggggacat gacatcaata ggtttctgga atgagggact ctttctcccc 2550

 gtgttttgct ttgtgttcac attttctttt ctaatggcat tgaaacttta 2600

 aaaaaaatgg attcaactgt ttttgcagaa tgtagaaagt attctgtgtc 2650

 cttggttaaa gaaatccact tgtgaagtgt gcctggaaaa tgaaagtttg 2700

 tgttttttaa agaggaatat ttgaaactgc tttctatgca tgcttagctg 2750

 gagaaaagta caggcaggcg tcccatctcc cagccacttc tcaaaggtgc 2800

 tgctgtgttt taaagaccag gtacagccag ggcagtattt gcaaggacat 2850

 tcctgcttac tttatccctt tggttggaaa gctctagatg attcccgcag 2900

 ctcctccaga ccccgcctcc ctgccctccc cagctggtct gggaagaggt 2950

 ggtctgctga cctgtggtat ctcagagggg acgttcctcc tcctccctgt 3000

 gcaccaggtg ggctgcaccc tcctgcctat tcaggatgtg gatgccacag 3050

 gagagcagca ggcagtggaa acttcagttg cactggttct cctggtggca 3100

 aaggcatgaa gcacaggggt cgattaatcc aggctactag aaagctccag 3150

 agcaaagtgt gcgggtccca caaatgcttg gctggtgggg tctggatcag 3200

 tgctgagata gagttggcag aagaagcaga ggcactctgc ttgctttcct 3250

 agccagtcct cccctaacaa cacaacacaa caacacacac aatctcagct 3300

 gcgccattct gtgcaatccc agtgaccaaa tcccttcctt gcccacctct 3350

 atgtcagcag gactgaccac atcactcccc cgagttccca ccaccagcat 3400

 ttcctccaac ctttttccat cacaaccagt tagaacccta caggcaacaa 3450

 ggccttctag aatccgctta acccttggct gataacaggc aaatttcagt 3500

 ctgctacact ttgttaggtc cagaaggagc tgcccatact actttcttat 3550

 gagcatgctc agtatggcat atggacatgt aatgtcacat ctttgtggag 3600

 tgtgattttc tttttttaca tatttgtatg cagtagagag cctgttgtag 3650

 aaaacgctcc ctgtatcttg ctgtactgtt aaagaaagct gaattccaca 3700

 ttgccaacaa aagcgtgaaa atgttcatga accttcctcc aggaaaagcc 3750

 attcaagcct gattattttt ctaagtaact tcaattaaat tgaagaaaaa 3800

 agag 3804

<210> 4365
<211> 170
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 343-382, 1239-1264
<223> Unknown amino acid

<400> 4365
 Met Leu Ser Trp Arg Lys Val Gln Ala Gly Val Pro Ser Pro Ser
   1               5                  10                  15

 His Phe Ser Lys Val Leu Leu Cys Phe Lys Asp Gln Val Gln Pro
                  20                  25                  30

 Gly Gln Tyr Leu Gln Gly His Ser Cys Leu Leu Tyr Pro Phe Gly
                  35                  40                  45

 Trp Lys Ala Leu Asp Asp Ser Arg Ser Ser Ser Arg Pro Arg Leu
                  50                  55                  60

 Pro Ala Leu Pro Ser Trp Ser Gly Lys Arg Trp Ser Ala Asp Leu
                  65                  70                  75

 Trp Tyr Leu Arg Gly Asp Val Pro Pro Pro Pro Cys Ala Pro Gly
                  80                  85                  90

 Gly Leu His Pro Pro Ala Tyr Ser Gly Cys Gly Cys His Arg Arg
                  95                 100                 105

 Ala Ala Gly Ser Gly Asn Phe Ser Cys Thr Gly Ser Pro Gly Gly
                 110                 115                 120

 Lys Gly Met Lys His Arg Gly Arg Leu Ile Gln Ala Thr Arg Lys
                 125                 130                 135

 Leu Gln Ser Lys Val Cys Gly Ser His Lys Cys Leu Ala Gly Gly
                 140                 145                 150

 Val Trp Ile Ser Ala Glu Ile Glu Leu Ala Glu Glu Ala Glu Ala
                 155                 160                 165

 Leu Cys Leu Leu Ser
                 170

<210> 4366
<211> 4162
<212> DNA
<213> Homo sapien

<400> 4366
 ggaatataat ttccccaaga gaatttgttg atttctccta tactgtgggc 50

 tataaagaag ggcttttatc ttgtggaata agtcttgact gggatgaaaa 100

 gagaccagaa tttgttcgag gatataacca tccctgtggt tggttttgtg 150

 ttccacttaa agacaaccca aaccagagtc ttttgacagg atatattcag 200

 acagatctgc gtgggatgat tcctcagtct gcggtagata cagccatggc 250

 aagcacttta accaacttct atggtgattt acgaaaagct ttatgagagg 300

 caaaatacat tcaaacttgt agtactacag atcaactctc tcagctacat 350

 ggcctgtaaa aatcattgat tccacttttc tgcatagccg gtagaaaaat 400

 ttgaaatgtt tttggttcac tagtacaatg tttggtttta ttcctaaagt 450

 aaatagctat ctaagagagg gcattttcac tttttttttt ttaaattttg 500

 agacaggctc tcactctgtt gcccatgctg gagggcagtg gtatgatcac 550

 agctcactgc agctttgatc tgaccgctca aggggttatt ctacctcagc 600

 ctcctgaata gctgggaata caggtgcacg ccactatgca tggctaattt 650

 ttgtttaatt ttttgtagag atgtggtcac actgtgttgc ccaggctggt 700

 cttgaactcc tggcctcaag tcattcccca ccttagcctc ccaaagtgtt 750

 gggattataa gcgtgagcca ccatgcctgg ccccaattta aaatgtggaa 800

 ttcagttggt gtccaagact tatcttgaga ctcttaaaag catcagtctg 850

 taactagaac aaatacggtc ttagatttac ccaagtgcct agatatcatt 900

 ttataatgat tagaattgag tattgtgggt cccctaattc tgtgggtgcc 950

 ttaagtgaga atttctaaat gattttcaca ttctaaatga ctttgggttt 1000

 tgaactctcc atctagttta cttctaaaat gggaacttga ggcaattcag 1050

 gtatccaggc aaatctttgt atatattttt ttgtgtacat gcacacatct 1100

 cgaaatccat ttccgtgttt aatgttagtt gtttatgtgt tagtattcct 1150

 gtgtctactg ttttgttgtt gttaatatgg gtaaagtgag ccctgaaata 1200

 catgctaaac aagacatgaa atgcagaaag gtacatagtg tttcaagtgc 1250

 atggtagttt gatctgtgtt ttactttatt gtgttttctt gagtgtaaag 1300

 aaagaataaa tcaaagttct tcatacccat tttgacaaag tggaacagtg 1350

 gagctgtttt ttgcttttgt ttttatttat tttttgccac tggtgatgat 1400

 agatttcaaa aaacaaaagg tggcagcagc acaatgttca tggtgaatta 1450

 tctcatagta tctagattga tcaagatctg acagaaggaa tgcacaaagg 1500

 attctatatt cttaatgatt tattaattac caggatcctt ttctaaattg 1550

 aatgtacttt tgaattacta ggtttcttct ttttttttgt tctgcaatag 1600

 tgaaagaaaa ctcagtagtt tagtttcagt ttctcatgga aattggtaaa 1650

 tgttagtttt gacttcatct attttttatt tgtttttatt agcgtagagt 1700

 aggaagtctc atattctact gttctatcta ggatggtgaa attccaaagg 1750

 tgcctaactt gagtaaggga tttgtgacaa gatagtacac attactataa 1800

 gggctattat ttcctgaact ggatgtccct aaaagcaaat aaactgccca 1850

 ctatctctac tctagtgctc tctttgtcct tatcaacata tacctccaat 1900

 aagtaattac ataattcacc gttaaacatg gacccactct aggtaattac 1950

 cctcatggaa acattttcac tgtgagaatg atgaatttta aaattatgtt 2000

 tgaatcacct aaaatgtatg tgcagcttct agatggcccc ttagatctgc 2050

 tgggctctag ctgtgtactt taaaaaaaca aaaacagctt tattgatata 2100

 taatttacat attatgtaat ttacccactt ttaagtatct aattcagtga 2150

 tgttttaata catatgtaga actatgcagc tatcagcaca atctggattt 2200

 agaacgtttc catcatttca aaagattcct tttgtctttt ttgcagactc 2250

 atacctaaca caaatctaaa gtttatcact gttgccagga taattacagc 2300

 aggttatgtt tggtttcatt tttaagagtg gaggtgttca tgattctaag 2350

 ctcaggaatc ttgtgatcat gtattaaata tgttatctca tactataatg 2400

 ataaaaaagc ttaatgatgt gggttgggat ggatattaac ataaataatt 2450

 gagtccgctg cttctatagc aatgctgtag gatagaacaa taatgtaagt 2500

 gatatatgta attaaaaaat tctagaagcc acattaaaaa ataaaaataa 2550

 acagctgaag ttaattttaa tattttattt aactcaatac atccaaaatg 2600

 ttatcatttt aacatgtaat tgatgtaaag atttattctg atagtttgta 2650

 ctatttcttg tactaatttt ttgaaatctg gtatgcattt tacaaatttg 2700

 ggcaaaccac attttaagtg ctcattagcc acatgaggcc agtggatact 2750

 gtgttgaata gcacagtcct atagcatatt tattaatttg tcttgtagta 2800

 agatgaaata gacaataata cggaataata tcttaaatgg aaatctttgt 2850

 tagtctctag agccttcatt gcttgataaa taggacatct aaactttaga 2900

 tataaatcag ttgtcaatga gataaaatta ttgccagcaa atattttcct 2950

 tcaaagataa gtaacttttg atatggcagt tggtgaaatg aaagaatata 3000

 atctgccttc ttgttaaatg gttgactatt ctgtagcttg taggtagtac 3050

 gtattagaaa cttgtgtatg tgggaaatat ttggcataat actgttttca 3100

 gtatatagta gctttttttt aaggaaatta gtttcataca agaaaaagat 3150

 tattataaaa gtgatacttt tgcatgaaat attagtttgt gttgataact 3200

 cttagttaac ccttaaagct taaaacagta ctcaaaaaaa aataatgaga 3250

 atctagtatt ctgtagttaa ctaatctata agataaattg ctaaagtact 3300

 agggagcttg taaatcttaa aaatcttttt atttcagtgt tcattcaggt 3350

 tggatatatt tgaaattgta gatttctatc tgtacaacat ctcctagtta 3400

 atagaatttt tttccttccc ctcccttctc tctcctcctc cttttctaac 3450

 caaagggcat tttatcaaca atcatgctga attcaattaa tatctcaagc 3500

 taaaaaacta tgtaattgag gttgtatctg gagaagatgg gaaaacattg 3550

 tataatttaa gcccttaatt gtctgttgag cttttagggc tgagtaattg 3600

 cctttcatac aaataaaagc tttaactctt ttctcaagag tgtaccaccg 3650

 tccttagaat caggtgtttt aaatccagtt tcttttaatt aaatgggact 3700

 gtagtgatcc ctaccctgta gagaaatcaa cagaactaga gaagctaagg 3750

 gcttgatcag gtttccccta gaacctgtgt tgcctgcctg ctgtatcttc 3800

 catgtctttc ttattcaact tctagaagta gagaaggttg ggacttgagt 3850

 gtagaagaaa catcagaata atttcaaaaa acaggaagtt ggaactataa 3900

 tttttaaatt attgtattgt ttttacggat tttacatgta tagttaaata 3950

 ttaaaattca tctcttgcag ttcaataaaa gctatagtat agattttatt 4000

 tttaagaagt ttatataatt cttttgtgag ccaatatgta aaactagaat 4050

 atttattaaa ctaataatat gtattagtat caataaaata tgtatttatt 4100

 tttaaattgg tatgaaacaa aataaaaatt tgtagacact cttaaaaaaa 4150

 aaaaaaaaaa aa 4162

<210> 4367
<211> 3471
<212> DNA
<213> Homo sapien

<400> 4367
 tttgctgagg ggcaggcaca ggagtcctgg ctgagctcat ggcctgaggc 50

 tgcctagcgg ccacggggaa tggttgcaat ggcggaggca gaggcagggg 100

 tggcagtgga ggtccgtgga ctgccccctg ccgtgcccga cgagctgctc 150

 actctctact ttgaaaaccg ccgacgctct ggagggggac ctgtgttgag 200

 ctggcagaga ctgggctgtg ggggcgtcct caccttcaga gagcctgcag 250

 acgccgagag ggtcttggcc caggcagatc atgaactaca tggtgcccag 300

 ctgagcctgc ggccagctcc accacgagcc cctgcacgcc tgctgctcca 350

 aggactgccc cctggcacca cgccccagcg cttggagcag catgtccagg 400

 ccttgctgcg ggcctcgggg ctcccagtac agccttgctg tgccttggcc 450

 agcccccggc cagaccgggc tctggtccag ttgcccaagc ccctttctga 500

 ggcagatgtc cgtgtcctgg aggagcaggc ccagaatctg ggcctggagg 550

 ggaccttggt gtccctggcc cgggttcccc aggcccgagc ggtgcgtgtg 600

 gtgggggatg gtgcctctgt ggacctgctg ttgctggagt tgtacctgga 650

 gaatgagcgc cgcagtggtg gggggcccct ggaggacctg caacgcctac 700

 ccgggcccct gggcactgtt gcctccttcc agcagtggca agtggcagaa 750

 cgagtgttgc agcaggagca ccggttgcag ggctcagagc tgagccttgt 800

 cccccactac gacgtcctgg agcccgagga gctggctgag aacaccagtg 850

 gaggggacca cccgtccacc caggggccta gggctaccaa gcatgctctc 900

 ctgaggaccg gagggttggt gacggctctg cagggtgcag ggactgtgac 950

 aatgggctct ggcgaggaac cagggcagtc aggggcctct ctgaggacag 1000

 gtcccatagt gcagggtaga gggattatga caacaggctc tggccaggaa 1050

 ccagggcagt cagggacctc tctgaggaca ggtcccatgg ggtctctggg 1100

 acaggcagag caagtcagct cgatgcccat ggggtctctg gaacatgagg 1150

 ggctggtaag cctgaggcct gtggggttgc aggaacagga ggggcccatg 1200

 agcctggggc ctgtggggtc tgcaggccca gtggagacct ctaaggggtt 1250

 gccggggcag gagggcctgg tggaaattgc catggactca ccagagcaag 1300

 aggggctggt gggtcccatg gagatcacca tggggtctct ggagaaggca 1350

 gggcctgtga gcccaggatg tgtgaagctg gcagggcagg agggcctggt 1400

 ggagatggtg ctattgatgg agccaggggc gatgcgcttc ctgcagctct 1450

 accatgagga ccttcttgcg ggcctgggag acgtcgctct cttgccactt 1500

 gaaggaccgg atatgactgg ctttcggctc tgtggagccc aggcttcctg 1550

 ccaggcggct gaggagtttc tgcggagcct gctgggcagc attagctgcc 1600

 atgtgttgtg cctggagcac tcgggcagcg ccaggtttct cctgggccca 1650

 gaagggcagc accttctcca ggggctggag gctcagttcc agtgtgtctt 1700

 tgggacagag cgcctggcca cagccacgtt ggacacaggc cttgaagagg 1750

 tggaccctac cgaggccctc ccagtgctcc ctggcaacgc ccacaccctg 1800

 tggaccccag acagtacagg tggtgaccag gaggacgtga gcctggagga 1850

 ggtccgagaa ctgctggcca ccctggaggg cctagaccta gacggggagg 1900

 actggctgcc tcgggagctg gaggaggaag ggcctcagga gcagccagag 1950

 gaggaggcga ccccagggca tgaggaggag gagcctgtgg cccccagcac 2000

 tgtggcaccc aggtggctgg aggaggaggc cgctctgcag ctggccctcc 2050

 accggtcact ggagcctcaa ggtcaggtgg ctgagcagga ggaggctgct 2100

 gccctgcggc aagccctaac cctctccctg ctggagcagc ccccgttgga 2150

 ggcagaagag cccccagatg gggggactga tggcaaggcc cagctggtgg 2200

 tgcactcggc ctttgagcag gatgtggagg agctggaccg ggcgctcagg 2250

 gctgccttgg aggtccacgt ccaggaggag acggtggggc cctggcgccg 2300

 cacactgcct gcagagctgc gtgctcgcct ggagcggtgc catggtgtga 2350

 gtgttgccct gcgtggtgac tgcaccatcc tccgtggctt cggggcccac 2400

 cctgcccgtg ctgcccgcca cttggtggca cttctggctg gcccctggga 2450

 tcagagtttg gcctttccct tggcagcttc aggccctacc ttggcggggc 2500

 agacgctgaa ggggccctgg aacaacctgg agcgtctggc agagaacacc 2550

 ggggagttcc aggaggtggt gcgggccttc tacgacaccc tggacgctgc 2600

 ccgcagcagc atccgcgtcg ttcgtgtgga gcgcgtgtcg cacccgctgc 2650

 tgcagcagca gtatgagctg taccgggagc gcctgctgca gcgatgcgag 2700

 cggcgcccgg tggagcaggt gctgtaccac ggcacgacgg caccggcagt 2750

 gcctgacatc tgcgcccacg gcttcaaccg cagcttctgc ggccgcaacg 2800

 ccacggtcta cgggaagggc gtgtatttcg ccaagcgcgc ctccctgtcg 2850

 gtgcaggacc gctactcgcc ccccaacgcc gatggccata aggcggtgtt 2900

 cgtggcacgg gtgctgactg gcgactacgg gcagggccgc cgcggtctgc 2950

 gggcgccccc tctgcggggt cctggccacg tgctcctgcg ctacgacagc 3000

 gccgtggact gcatctgcca gcccagcatc ttcgtcatct tccacgacac 3050

 ccaggcgctg cccacccacc tcatcacctg cgagcacgtg ccccgcgctt 3100

 cccccgacga cccctctggg ctcccgggcc gctccccaga cacttaaccg 3150

 aaggggccac cctctggcct cctgcttccc aggctcccag ctccgcacag 3200

 gctgatgctc cccgccccca actgtggccg cctgagctgt ccccggggac 3250

 gcccctgcct ccctctgcgg gctccagaag gcggtgtggg ggatggcggt 3300

 cagcagcggc cgagaggggc tgggctaggt cccagcctgg gccgacccca 3350

 ccaccagggg tcagcagagc ccaggaggcg acactgcccg cccgccgctc 3400

 ccagacctcg cccgagtcgg ctctgttgtt tgaataaacg tgaacgtgaa 3450

 cccaggcgga agggacccgg g 3471

<210> 4368
<211> 1025
<212> PRT
<213> Homo sapien

<400> 4368
 Met Val Ala Met Ala Glu Ala Glu Ala Gly Val Ala Val Glu Val
   1               5                  10                  15

 Arg Gly Leu Pro Pro Ala Val Pro Asp Glu Leu Leu Thr Leu Tyr
                  20                  25                  30

 Phe Glu Asn Arg Arg Arg Ser Gly Gly Gly Pro Val Leu Ser Trp
                  35                  40                  45

 Gln Arg Leu Gly Cys Gly Gly Val Leu Thr Phe Arg Glu Pro Ala
                  50                  55                  60

 Asp Ala Glu Arg Val Leu Ala Gln Ala Asp His Glu Leu His Gly
                  65                  70                  75

 Ala Gln Leu Ser Leu Arg Pro Ala Pro Pro Arg Ala Pro Ala Arg
                  80                  85                  90

 Leu Leu Leu Gln Gly Leu Pro Pro Gly Thr Thr Pro Gln Arg Leu
                  95                 100                 105

 Glu Gln His Val Gln Ala Leu Leu Arg Ala Ser Gly Leu Pro Val
                 110                 115                 120

 Gln Pro Cys Cys Ala Leu Ala Ser Pro Arg Pro Asp Arg Ala Leu
                 125                 130                 135

 Val Gln Leu Pro Lys Pro Leu Ser Glu Ala Asp Val Arg Val Leu
                 140                 145                 150

 Glu Glu Gln Ala Gln Asn Leu Gly Leu Glu Gly Thr Leu Val Ser
                 155                 160                 165

 Leu Ala Arg Val Pro Gln Ala Arg Ala Val Arg Val Val Gly Asp
                 170                 175                 180

 Gly Ala Ser Val Asp Leu Leu Leu Leu Glu Leu Tyr Leu Glu Asn
                 185                 190                 195

 Glu Arg Arg Ser Gly Gly Gly Pro Leu Glu Asp Leu Gln Arg Leu
                 200                 205                 210

 Pro Gly Pro Leu Gly Thr Val Ala Ser Phe Gln Gln Trp Gln Val
                 215                 220                 225

 Ala Glu Arg Val Leu Gln Gln Glu His Arg Leu Gln Gly Ser Glu
                 230                 235                 240

 Leu Ser Leu Val Pro His Tyr Asp Val Leu Glu Pro Glu Glu Leu
                 245                 250                 255

 Ala Glu Asn Thr Ser Gly Gly Asp His Pro Ser Thr Gln Gly Pro
                 260                 265                 270

 Arg Ala Thr Lys His Ala Leu Leu Arg Thr Gly Gly Leu Val Thr
                 275                 280                 285

 Ala Leu Gln Gly Ala Gly Thr Val Thr Met Gly Ser Gly Glu Glu
                 290                 295                 300

 Pro Gly Gln Ser Gly Ala Ser Leu Arg Thr Gly Pro Ile Val Gln
                 305                 310                 315

 Gly Arg Gly Ile Met Thr Thr Gly Ser Gly Gln Glu Pro Gly Gln
                 320                 325                 330

 Ser Gly Thr Ser Leu Arg Thr Gly Pro Met Gly Ser Leu Gly Gln
                 335                 340                 345

 Ala Glu Gln Val Ser Ser Met Pro Met Gly Ser Leu Glu His Glu
                 350                 355                 360

 Gly Leu Val Ser Leu Arg Pro Val Gly Leu Gln Glu Gln Glu Gly
                 365                 370                 375

 Pro Met Ser Leu Gly Pro Val Gly Ser Ala Gly Pro Val Glu Thr
                 380                 385                 390

 Ser Lys Gly Leu Pro Gly Gln Glu Gly Leu Val Glu Ile Ala Met
                 395                 400                 405

 Asp Ser Pro Glu Gln Glu Gly Leu Val Gly Pro Met Glu Ile Thr
                 410                 415                 420

 Met Gly Ser Leu Glu Lys Ala Gly Pro Val Ser Pro Gly Cys Val
                 425                 430                 435

 Lys Leu Ala Gly Gln Glu Gly Leu Val Glu Met Val Leu Leu Met
                 440                 445                 450

 Glu Pro Gly Ala Met Arg Phe Leu Gln Leu Tyr His Glu Asp Leu
                 455                 460                 465

 Leu Ala Gly Leu Gly Asp Val Ala Leu Leu Pro Leu Glu Gly Pro
                 470                 475                 480

 Asp Met Thr Gly Phe Arg Leu Cys Gly Ala Gln Ala Ser Cys Gln
                 485                 490                 495

 Ala Ala Glu Glu Phe Leu Arg Ser Leu Leu Gly Ser Ile Ser Cys
                 500                 505                 510

 His Val Leu Cys Leu Glu His Ser Gly Ser Ala Arg Phe Leu Leu
                 515                 520                 525

 Gly Pro Glu Gly Gln His Leu Leu Gln Gly Leu Glu Ala Gln Phe
                 530                 535                 540

 Gln Cys Val Phe Gly Thr Glu Arg Leu Ala Thr Ala Thr Leu Asp
                 545                 550                 555

 Thr Gly Leu Glu Glu Val Asp Pro Thr Glu Ala Leu Pro Val Leu
                 560                 565                 570

 Pro Gly Asn Ala His Thr Leu Trp Thr Pro Asp Ser Thr Gly Gly
                 575                 580                 585

 Asp Gln Glu Asp Val Ser Leu Glu Glu Val Arg Glu Leu Leu Ala
                 590                 595                 600

 Thr Leu Glu Gly Leu Asp Leu Asp Gly Glu Asp Trp Leu Pro Arg
                 605                 610                 615

 Glu Leu Glu Glu Glu Gly Pro Gln Glu Gln Pro Glu Glu Glu Ala
                 620                 625                 630

 Thr Pro Gly His Glu Glu Glu Glu Pro Val Ala Pro Ser Thr Val
                 635                 640                 645

 Ala Pro Arg Trp Leu Glu Glu Glu Ala Ala Leu Gln Leu Ala Leu
                 650                 655                 660

 His Arg Ser Leu Glu Pro Gln Gly Gln Val Ala Glu Gln Glu Glu
                 665                 670                 675

 Ala Ala Ala Leu Arg Gln Ala Leu Thr Leu Ser Leu Leu Glu Gln
                 680                 685                 690

 Pro Pro Leu Glu Ala Glu Glu Pro Pro Asp Gly Gly Thr Asp Gly
                 695                 700                 705

 Lys Ala Gln Leu Val Val His Ser Ala Phe Glu Gln Asp Val Glu
                 710                 715                 720

 Glu Leu Asp Arg Ala Leu Arg Ala Ala Leu Glu Val His Val Gln
                 725                 730                 735

 Glu Glu Thr Val Gly Pro Trp Arg Arg Thr Leu Pro Ala Glu Leu
                 740                 745                 750

 Arg Ala Arg Leu Glu Arg Cys His Gly Val Ser Val Ala Leu Arg
                 755                 760                 765

 Gly Asp Cys Thr Ile Leu Arg Gly Phe Gly Ala His Pro Ala Arg
                 770                 775                 780

 Ala Ala Arg His Leu Val Ala Leu Leu Ala Gly Pro Trp Asp Gln
                 785                 790                 795

 Ser Leu Ala Phe Pro Leu Ala Ala Ser Gly Pro Thr Leu Ala Gly
                 800                 805                 810

 Gln Thr Leu Lys Gly Pro Trp Asn Asn Leu Glu Arg Leu Ala Glu
                 815                 820                 825

 Asn Thr Gly Glu Phe Gln Glu Val Val Arg Ala Phe Tyr Asp Thr
                 830                 835                 840

 Leu Asp Ala Ala Arg Ser Ser Ile Arg Val Val Arg Val Glu Arg
                 845                 850                 855

 Val Ser His Pro Leu Leu Gln Gln Gln Tyr Glu Leu Tyr Arg Glu
                 860                 865                 870

 Arg Leu Leu Gln Arg Cys Glu Arg Arg Pro Val Glu Gln Val Leu
                 875                 880                 885

 Tyr His Gly Thr Thr Ala Pro Ala Val Pro Asp Ile Cys Ala His
                 890                 895                 900

 Gly Phe Asn Arg Ser Phe Cys Gly Arg Asn Ala Thr Val Tyr Gly
                 905                 910                 915

 Lys Gly Val Tyr Phe Ala Lys Arg Ala Ser Leu Ser Val Gln Asp
                 920                 925                 930

 Arg Tyr Ser Pro Pro Asn Ala Asp Gly His Lys Ala Val Phe Val
                 935                 940                 945

 Ala Arg Val Leu Thr Gly Asp Tyr Gly Gln Gly Arg Arg Gly Leu
                 950                 955                 960

 Arg Ala Pro Pro Leu Arg Gly Pro Gly His Val Leu Leu Arg Tyr
                 965                 970                 975

 Asp Ser Ala Val Asp Cys Ile Cys Gln Pro Ser Ile Phe Val Ile
                 980                 985                 990

 Phe His Asp Thr Gln Ala Leu Pro Thr His Leu Ile Thr Cys Glu
                 995                1000                1005

 His Val Pro Arg Ala Ser Pro Asp Asp Pro Ser Gly Leu Pro Gly
                1010                1015                1020

 Arg Ser Pro Asp Thr
                1025

<210> 4369
<211> 1648
<212> DNA
<213> Homo sapien

<400> 4369
 cgtccacaag ttcagagcca tgctgggcaa gaaccggctc atctttccag 50

 gcgagaaggt gctcttggcg tggtctgggg ggccttcgtc cagctccatg 100

 gtctggcagg ttcttgaggg cctgagccaa gattctgcca aaagactgcg 150

 ctttgtggca ggagtcatct ttgttgacga gggagcagcc tgtggccaga 200

 gcctagagga gagatcaaag accctggccg aagtgaagcc cattctgcaa 250

 gcaactgggt tcccatggca tgtggtggcc ttagaggagg tgttcagcct 300

 gccaccgtcg gtgctttggt gctctgccca ggagctggtg ggatccgagg 350

 gggcctacaa ggcggccgtg gacagcttcc tccagcagca gcatgtgctg 400

 ggggccgggg gtggtcctgg cccgactcaa ggggaggaac agccacccca 450

 gcccccgctg gacccccaga acctggcaag accgcctgcc cctgcccaga 500

 ctgaggctct ttcccaactg ttctgctcag tgaggacact gactgccaag 550

 gaggagcttc tgcagaccct gcggacccac ctgatcctcc acgtggcccg 600

 agcccacggc tactccaagg tcatgactgg ggacagctgc acacgcttgg 650

 ctatcaagct catgaccaac ctggcgctgg gtcgaggggc cttcctggcc 700

 tgggatacgg gcttctcgga tgagcggcac ggggacgtgg tggtggtgcg 750

 gcccatgcgg gaccacaccc tgaaggaggt cgctttctac aaccgcctgt 800

 tctccgttcc ttctgtcttc acaccagccg tcgacaccaa ggcccctgaa 850

 aaggccagca tccaccggct gatggaggcc ttcatcctca ggctgcagac 900

 ccagttcccc tccactgtca gcactgtgta caggacaagt gagaagctgg 950

 tgaagggccc ccgggatggc cctgctgctg gcgactccgg cccccgctgc 1000

 ctcctctgca tgtgtgccct ggacgtcgac gccgctggtc tgtgtttcat 1050

 gctcttgggg tgatgggggg agggagccag ggagtgggtg tgggggctca 1100

 gcagccccag gctccgtcac cccctctctg cttgcagaca gtgccacggc 1150

 ttttggggct cagacctcct cgcgtctctc ccggatgcag tcacccatcc 1200

 ccctgactga gacccggaca cccccggggc cctgctgttc tccaggggtg 1250

 ggctgggccc agcgctgcgg ccagggggcc tgcaggaggg aggaccccca 1300

 agcctgcatt gaggagcagc tgtgctacag ctgccgcgtg aacatgaagg 1350

 acttgccctc actggacccc ctgccgccgt acatcctggc tgaggcccag 1400

 ctccgcacac agagggcctg gggcttgcag gagatccggg actgtctgat 1450

 tgaggacagt gacgacgagg cgggccagag ctgagcgtga ggacgtgctt 1500

 gccgggacag caggcagtgg ccacctggta caccacactg gagccggaag 1550

 gcaaggacgg gggactggcc tctgattgtc catttgtata aataaaacat 1600

 tttttaatta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1648

<210> 4370
<211> 2437
<212> DNA
<213> Homo sapien

<400> 4370
 aaaatgctac agatggaatt tgtcctccta atactcatat gttggaacct 50

 aatatgactc tatctggaga cagtgatagt aggagatagt taagattaca 100

 ggtgtgagcc accacgccca tccaggagca gctctttttt taaaagtgag 150

 tttcagcaaa cagtattgaa taaaagcatc cttttcatat cttcatatac 200

 tactttatga tgcaataatt tactgttcct atacatatta taaggtagaa 250

 aaaagttttt aaatccttat aaagaggatg cagtttagaa ggttaatatg 300

 tcagcttacc cagacatatt ctatcaagga aaacctagtg gtagcaataa 350

 atctttggaa aggacttctt atactcatgt acctttaaaa catctaagca 400

 atttaaaata atccctgttg agtttaaatt cgagatgcat ttaggtaaat 450

 cggataaatt caacatttga ataaatccgt caggttttag atggtgggat 500

 tgatgaactt tggtactttc tcaatccaaa actaatttat ttggaactag 550

 tacgttatgg cttctcagtc atgaaaagct cagttatttg gggtctacat 600

 tttctcactg agagccttga tattttgcct tctttgttat gcattataac 650

 ttgactgtat caccactgag tatctgctgt atcagaagtt cagaagaaaa 700

 ggtaaaactg aaatcagaat gggggtagag gaagttaaaa acaagttatt 750

 taaaaagaac tcttggtttt tggatgactt gaattctgtt aaatctgtgt 800

 tcttggcctt gcacttccgt tcctcttcca tctctatccc tgctagtcac 850

 aatggcattt tagaactaga atgccactct gtagaggttt tcccttttgc 900

 tctgttgtgc ctatttgtct aattcatatc tttctgtgga gtttcatatg 950

 tccttaatct aaagtaactt aaaattggaa tggaagaaca agtttcagaa 1000

 ttatttacag tcttatacat agaacttcta gtgtaatgtt tggttgtaag 1050

 gagaatgtga atttgcaggt aaatgaattg tatggcaacc agacagatcc 1100

 ctggggtttg ggagaaatag agcttgagat ttgaaaaaaa ggtacaaggt 1150

 acaaaacaac tctaactgcc agtgccaaag ggctaatttt taagcatgta 1200

 agctttacca cagtcttgaa aaaaatatta accataggtt cattcagctg 1250

 ttttatttaa cccttagttc cctggtggtt gatttttttt ttaaatgggt 1300

 ctccagcttt ccagtgaaat gtgacactct caatagaatg cataatgttg 1350

 gtttctaaag ttacactcca taattattgt tattctgtag aaaactgtac 1400

 agaaggtaaa tagaatagct tcaatgggaa tataatttaa atttttttaa 1450

 ttttataaaa atttatttcc attgcattaa aagaaatggg tagcatgtgt 1500

 ctttcagaga aaggagctat ttggttattc actttgtcaa tcttaggttt 1550

 ttttaaatct ttaaacaatt tcttctttgt gatgataaaa ataatataaa 1600

 tttactgttt ctgatcatga ctgagtctat tacttgtcat ggcttttgta 1650

 cgcaactgtg ttttaaaaat accggttttg cctctttggt tacatgtggt 1700

 gagcatggat gtcaagatta tttttcaact agattattca atttgtttta 1750

 tatttcttat acttaatact tatgactaca gtccaaatca gtcttttaga 1800

 aggtgctctt gctaactgtg gaatatttga cgacatgaaa gtcctttttc 1850

 tttgctttca gtggttggct ttcactgaaa gaaagtgtaa aaaaagtcag 1900

 aatttatagc tttcactatg tccaagacta ggactgggtt ataaagattt 1950

 tcttttgtga aggaaaataa aagaaaattt gccactactg catttacttt 2000

 actattgtaa acttaagatt cattccttag tctttggaat tttgatgtct 2050

 caaaaccaga tgagtggaag tgctgaattt gcaaaataaa gctaagaatg 2100

 cttaactctg cactttaagt tctactctga ccaaattgaa gatgagcaga 2150

 gcagccctga acagcatttt gtttatacag tcttgtttaa gaatagaatt 2200

 tttttaactc ttcatttttt gtctctgtgg aagctgtgta actcttttta 2250

 aaatgcaatt taaaacattt tgttattcta acaattctct caaaaaacag 2300

 catttccaat ggtaatcggt attgttacgc tgtacttatg tattccctgt 2350

 acctgaacac ttgttgctgc ctcacaagaa aatagaactt ttatgttaaa 2400

 aataaagtct gttcttcttg agtttttttc aatgaga 2437

<210> 4371
<211> 14
<212> PRT
<213> Homo sapien

<400> 4371
 Met Leu Lys Ile Lys Ser Val Leu Leu Glu Phe Phe Ser Met
   1               5                  10

<210> 4372
<211> 5061
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 332, 341
<223> Unknown base

<400> 4372
 gagctgccgg gttacctgct ttggggtttg aactggctgc tggttttatt 50

 cccctcccct gtctctggtc tctccgttct tcttttaggt tgctccaccc 100

 cggtcaggat caggcgaggg ggaaccagcc tgagtgcagc tgccaactcc 150

 cgccgagtgc gtctgcgaac tcccggagcg gagtcccgcg tgccgccacc 200

 tccccgcggg acgcactctc ctcgctcccc cgggccccgc gtcctccccc 250

 cggccaccct tccccacttt tccccccttt tccaatcaca tggcatttta 300

 agaatgccgg aaagatggcg gtagcggcgg cngcggcggc ngctgggccg 350

 gctggcgcgg gaggcggccg ggcgcagcgg agcgggctgc tggaagtttt 400

 ggtgcgggat cgctggcaca aagttctggt gaacttgagc gaggacgccc 450

 tggttctgag cagcgaggag ggcgctgcgg cgtacaacgg catcgggacc 500

 gccaccaatg gctcgttctg caggggcgcc ggggctgggc acccgggcgc 550

 gggcggcgcg cagcccccgg actcgcccgc cggggtccgc accgctttca 600

 ccgacctgcc cgagcaggtg cccgagtcca tctcgaacca gaagcgtggc 650

 gtgaaggtgc tgaagcagga gctgggcggg ctggggatca gcatcaaggg 700

 gggcaaggag aacaagatgc ccatcctcat cagcaagatc ttcaaggggc 750

 tggcggcgga ccagacccaa gccctgtacg tgggcgacgc catcctgtcc 800

 gtgaacggag ccgacctgcg ggacgccacc cacgacgagg cggtgcaggc 850

 gttgaagcgc gcgggcaagg aagtgctgct ggaagtgaag tacatgcgag 900

 aagccacgcc ctatgtgaag aaaggatccc cagtatccga gattgggtgg 950

 gaaacacctc cgcctgaatc ccctcggtta gggggcagca cctcagaccc 1000

 cccgtcatcg cagtccttct ccttccacag agaccggaaa agcatccccc 1050

 tcaaaatgtg ctacgtcact cggagtatgg ccttggccga ccctgagaac 1100

 aggcagcttg aaatccactc tccagatgct aagcacacgg tgatcctaag 1150

 gagcaaggac tcagccacgg cccaggcatg gttcagtgcc atccattcca 1200

 acgttaatga cctgctgacc cgagtgattg ctgaggtcag agagcagctg 1250

 gggaaaacag gcattgctgg gagccgagag attaggcatc ttggctggct 1300

 tgcagaaaag gtgccagggg agagcaagaa acagtggaaa ccagccctgg 1350

 ttgtgctgac tgagaaagac cttttaatct atgacagcat gccacggagg 1400

 aaggaagcct ggttcagccc agttcacaca taccctcttc ttgccaccag 1450

 gctggtccat tcaggtccag gaaagggatc accccaggct ggtgtggatc 1500

 tgtcctttgc aacgcgaact ggtaccaggc aagggattga aacacatctc 1550

 ttcagagcag agaccagcag ggacctctcc cactggacaa ggagcatagt 1600

 acagggttgc cacaattctg ctgaactcat tgctgaaatc agcactgctt 1650

 gcacctacaa aaaccaggag tgccgtttga ccatacatta tgagaatgga 1700

 ttttctatta ccactgaacc acaggagggt gcctttccca agaccatcat 1750

 acagtctcct tatgaaaagc tcaaaatgtc ttcagatgat ggaatcagga 1800

 tgctgtattt agattttgga ggcaaagatg gagagattca actggacctt 1850

 cattcctgcc ccaagccaat tgttttcatc attcattcct tcctgtcagc 1900

 taagattaca agactgggct tggtggcctg aagacagggg tgacttgcct 1950

 ttgagaaaag aagggctgca atgccaccag agaacgtgat gtcagacacc 2000

 atctgtagtg agcagcgcac cagatgtagc gtgctacagt cagctttagc 2050

 tctcaagagt cgtatgtaac tgtcccagac tcctctgtca gtttcagcaa 2100

 ctacaaggga taccctgcga aagtaccatg agaaatatca gagtaaaact 2150

 ttctagaaca gtacaaggtt aaagaggtga ggtgacggga aatacacagc 2200

 atagctttga aataatgaca accaaggaca tgaccattag aacagcatgt 2250

 gcagatctta atcatcccag ttcctaggca acttgttcac caggtacgca 2300

 agggccgaat agttgagaaa tggacatttt tacctactcc tcctagcccc 2350

 ctatccccag taacagtgat cccttttctt attgtgattt atttcctaat 2400

 tcttgctgag ttgactttcc cttgtaggaa aagaaaaata tttcaaatag 2450

 aaacccacct tttatttaag tatgaagcag ctgttacttt ttaaaaaatg 2500

 aattatcttt caatggtgta gaatgattcc aaagtgtctc cattagcata 2550

 tactgagcag gaattaaata aagcatcaga tactgatctg agctgtaagc 2600

 tggtagaatc tgagccaaag tagactgctt aaattgataa gctttgctaa 2650

 agagttgtat gcacaaagga tgattaattc tgggactata ctcacaccaa 2700

 ggtctgctgt cttatagcca agaattacag ctttatttat agagagtgaa 2750

 ttatgggtat tttttcagaa aatattgtca tctgatatac acataaaaca 2800

 actcacattg ttggagttaa ctaattatcc ccatttcatg gttttcagtg 2850

 gcaacttact gacccttgtt tttgcctgtg cttgtatgca tgcattttca 2900

 agcaagtaat aaagcagcct catttaattc tggataatgc tgggttttac 2950

 atatagactg aatgctataa tcaaatctat tgacagtatc tgcagttctt 3000

 tcagaattcc agggaaataa tataacgacc tgatatcttt ctacaggaat 3050

 attttcagac attatatagc acattactga tttaatgctt ttacttttat 3100

 ctttcaaaac aaattcacta aaaataacac ctattgattt tgaagtcact 3150

 tttctcaaac cttgaaaatg agctctagga tctctataaa catttctaac 3200

 acttttcctg tagtttacat agacagacat ctgttgttag acctgtgtgt 3250

 ttttaaagaa tcatatgtta acaaataccc atgcaaagag cttcaaaaag 3300

 tgaaaccgta ttaaaggaac acaatttttc tcactcagac atatttgttt 3350

 attgaattgc aaagttttat tttaaatcag catttcccca aagaatatat 3400

 catatgacgc tagttccaag gggcttgact gagtggtgtt ttgctggggg 3450

 gagacagggg tttgttaata cactttacta aatactgagc tgaaaaatgt 3500

 taaatagatt tcacgattgc ctccttgaag attttaaagt tcattgtggt 3550

 tcttcaaggc gaaatccggt gaaccattcc tcacacttac ctacaggact 3600

 cttttctaat ggagcatctt gtgaagctag tgggtttttt agtgttgtta 3650

 tttgtttttt gtttttaatg ctttagaaaa cacagcttta ggatattgac 3700

 tttttgttta tttctatttt caaatgctga aaagtcaagt cccagtttga 3750

 ataccataga aaagctttga tgcatttgta aattatattg cactctttca 3800

 ctatatattt tcaaaatcac tggaatgttg ttatacaaga gaattataat 3850

 tgtgtattgt aaataacata ttaaaataca tatattaatg ccaatagtta 3900

 aattcaacaa tatgtaatct aaggtgctcg gttctacatg aagtatgagt 3950

 taactgctca taattaagtt gccaagattc tattatatat ttatagacaa 4000

 attaaaatga tcataattac aaatatgatt tctttatcac ttaagctttg 4050

 ggctgattaa tatctgtgtg ggggtcaatg gaaactacat tctctacatt 4100

 tataaacatt taatttaatt atttatattt taggaaaata tatttgaata 4150

 aaattaatgc attttctaga gtaaattaaa atgttattag caagaaatag 4200

 aaaatttgac taagataatt gtgtatatga atcatttttc ccccaagtta 4250

 aaatgtatca taatagagag gctctaatga atcaatttcc aatactcatt 4300

 tctttcttat tttgaattca agttacaatg actttacact gtagatttta 4350

 atcttgtctg atgtgtgctg gtgtgtatga cacaaactca taagtctgga 4400

 tcatgcttgg gtacagtcaa tgaatcaacc gagtcacttt gaggaatttg 4450

 tttttgtcca atttgctctg tgctcaatcc catgaattat taaatttaca 4500

 atgtttgtcc ccaaatgaaa accaatataa atgaatgatg ttttaatctg 4550

 tactttatgg gaagttgcct atttgtcagt agatgtggtt aagtgagtcc 4600

 tctggtgcag tgacatcctt ttaagccatc tcatagggat ttaaagaagg 4650

 ccaataggaa tatagatatt ggtttttctt tctctgactt gaactaagta 4700

 ggagaaacca aaccataaac ctattacaaa ctacccaggc agaggcattt 4750

 acttaattca tcaactagtg caattaaaac cctgaaaaca catgatcctt 4800

 gttgactctg cttggttgaa gcaggaaaga atggtcttga tggtcagaaa 4850

 gttttaaaat taatgggcag ggcctttctg gaccctgttt tccaaacacg 4900

 ttagatattc cgtcttgagg ggattggagt aggctacagt gagggggtaa 4950

 tttttggatg tatctggact tttaaaaaat gtgcctatat ttatagcacc 5000

 atgaatatta tgtaaaattt atatatgaat taaataaata ttcacctctg 5050

 atttccagtg c 5061

<210> 4373
<211> 642
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 332, 341
<223> Unknown amino acid

<400> 4373
 Ala Ala Gly Leu Pro Ala Leu Gly Phe Glu Leu Ala Ala Gly Phe
   1               5                  10                  15

 Ile Pro Leu Pro Cys Leu Trp Ser Leu Arg Ser Ser Phe Arg Leu
                  20                  25                  30

 Leu His Pro Gly Gln Asp Gln Ala Arg Gly Asn Gln Pro Glu Cys
                  35                  40                  45

 Ser Cys Gln Leu Pro Pro Ser Ala Ser Ala Asn Ser Arg Ser Gly
                  50                  55                  60

 Val Pro Arg Ala Ala Thr Ser Pro Arg Asp Ala Leu Ser Ser Leu
                  65                  70                  75

 Pro Arg Ala Pro Arg Pro Pro Pro Gly His Pro Ser Pro Leu Phe
                  80                  85                  90

 Pro Pro Phe Pro Ile Thr Trp His Phe Lys Asn Ala Gly Lys Met
                  95                 100                 105

 Ala Val Ala Ala Ala Ala Ala Ala Ala Gly Pro Ala Gly Ala Gly
                 110                 115                 120

 Gly Gly Arg Ala Gln Arg Ser Gly Leu Leu Glu Val Leu Val Arg
                 125                 130                 135

 Asp Arg Trp His Lys Val Leu Val Asn Leu Ser Glu Asp Ala Leu
                 140                 145                 150

 Val Leu Ser Ser Glu Glu Gly Ala Ala Ala Tyr Asn Gly Ile Gly
                 155                 160                 165

 Thr Ala Thr Asn Gly Ser Phe Cys Arg Gly Ala Gly Ala Gly His
                 170                 175                 180

 Pro Gly Ala Gly Gly Ala Gln Pro Pro Asp Ser Pro Ala Gly Val
                 185                 190                 195

 Arg Thr Ala Phe Thr Asp Leu Pro Glu Gln Val Pro Glu Ser Ile
                 200                 205                 210

 Ser Asn Gln Lys Arg Gly Val Lys Val Leu Lys Gln Glu Leu Gly
                 215                 220                 225

 Gly Leu Gly Ile Ser Ile Lys Gly Gly Lys Glu Asn Lys Met Pro
                 230                 235                 240

 Ile Leu Ile Ser Lys Ile Phe Lys Gly Leu Ala Ala Asp Gln Thr
                 245                 250                 255

 Gln Ala Leu Tyr Val Gly Asp Ala Ile Leu Ser Val Asn Gly Ala
                 260                 265                 270

 Asp Leu Arg Asp Ala Thr His Asp Glu Ala Val Gln Ala Leu Lys
                 275                 280                 285

 Arg Ala Gly Lys Glu Val Leu Leu Glu Val Lys Tyr Met Arg Glu
                 290                 295                 300

 Ala Thr Pro Tyr Val Lys Lys Gly Ser Pro Val Ser Glu Ile Gly
                 305                 310                 315

 Trp Glu Thr Pro Pro Pro Glu Ser Pro Arg Leu Gly Gly Ser Thr
                 320                 325                 330

 Ser Asp Pro Pro Ser Ser Gln Ser Phe Ser Phe His Arg Asp Arg
                 335                 340                 345

 Lys Ser Ile Pro Leu Lys Met Cys Tyr Val Thr Arg Ser Met Ala
                 350                 355                 360

 Leu Ala Asp Pro Glu Asn Arg Gln Leu Glu Ile His Ser Pro Asp
                 365                 370                 375

 Ala Lys His Thr Val Ile Leu Arg Ser Lys Asp Ser Ala Thr Ala
                 380                 385                 390

 Gln Ala Trp Phe Ser Ala Ile His Ser Asn Val Asn Asp Leu Leu
                 395                 400                 405

 Thr Arg Val Ile Ala Glu Val Arg Glu Gln Leu Gly Lys Thr Gly
                 410                 415                 420

 Ile Ala Gly Ser Arg Glu Ile Arg His Leu Gly Trp Leu Ala Glu
                 425                 430                 435

 Lys Val Pro Gly Glu Ser Lys Lys Gln Trp Lys Pro Ala Leu Val
                 440                 445                 450

 Val Leu Thr Glu Lys Asp Leu Leu Ile Tyr Asp Ser Met Pro Arg
                 455                 460                 465

 Arg Lys Glu Ala Trp Phe Ser Pro Val His Thr Tyr Pro Leu Leu
                 470                 475                 480

 Ala Thr Arg Leu Val His Ser Gly Pro Gly Lys Gly Ser Pro Gln
                 485                 490                 495

 Ala Gly Val Asp Leu Ser Phe Ala Thr Arg Thr Gly Thr Arg Gln
                 500                 505                 510

 Gly Ile Glu Thr His Leu Phe Arg Ala Glu Thr Ser Arg Asp Leu
                 515                 520                 525

 Ser His Trp Thr Arg Ser Ile Val Gln Gly Cys His Asn Ser Ala
                 530                 535                 540

 Glu Leu Ile Ala Glu Ile Ser Thr Ala Cys Thr Tyr Lys Asn Gln
                 545                 550                 555

 Glu Cys Arg Leu Thr Ile His Tyr Glu Asn Gly Phe Ser Ile Thr
                 560                 565                 570

 Thr Glu Pro Gln Glu Gly Ala Phe Pro Lys Thr Ile Ile Gln Ser
                 575                 580                 585

 Pro Tyr Glu Lys Leu Lys Met Ser Ser Asp Asp Gly Ile Arg Met
                 590                 595                 600

 Leu Tyr Leu Asp Phe Gly Gly Lys Asp Gly Glu Ile Gln Leu Asp
                 605                 610                 615

 Leu His Ser Cys Pro Lys Pro Ile Val Phe Ile Ile His Ser Phe
                 620                 625                 630

 Leu Ser Ala Lys Ile Thr Arg Leu Gly Leu Val Ala
                 635                 640

<210> 4374
<211> 2935
<212> DNA
<213> Homo sapien

<400> 4374
 cacggctttg ttccggaaag cccttaggtg gagagcgatg tggggcgcgg 50

 cagggggatc gcgtagagga accttcgcgc accgcctctc cgggtctggg 100

 aatctgctga actccttgcc tctcttgggg tccctcgaac gccccagcta 150

 agaagggcgg gggccttgcc agggcgcgag caacatgacg ttcaaggtct 200

 tcctgtggct tctgtaaaga aatgttcacg tgggagcctg tccacatggg 250

 ctgtactaag gatctggcac gaggaagaaa tatcactgca gaacctgaag 300

 ccctccgttg gaagggtcgt tcactcgagt acctattcta agtaacagtg 350

 acacaaaaca catgttagaa aaaaacaaaa agtatggtag gttatactgt 400

 tttttaaaag aaacttttat ttatgccttt tgctgttaag tcctctaatt 450

 ttacattgga actgagtcat tcttggagca aaactagaat aggtttgtat 500

 ttgttttctt tttggatgtg tatctaaatt gtacataatt aagaaaaagc 550

 aagtaatgga aaagctggag atgtagaact tagttccttc taacttagta 600

 tgcaattgaa agcctcaagt caagactcct gtgtattgtt ttgtattagg 650

 actctattgt acaaatattt gagtacctta atatgagtca gttacttttt 700

 ctagatcttg gatccatgcc agacaacgca cattctgcag acactggtta 750

 ctccagtggc tccttactgg aaacataata tcagtgataa gtgctgtgaa 800

 gaaaataaaa caatgatgtg ctggtatgga tttttaactt ttttatgtga 850

 tgaaccacag aatgatggtt ttaaatgtat gaaatacata gaattgcaac 900

 agaaaccagt tatgaaataa tgaagatatt aaatatgaca tctatatttt 950

 agtaaagcat tagtgaggac tgtaaatgat ctttaaagaa tttggcttaa 1000

 atttaatcta aaattgctat caggtatttc acatcgctgt aatttttgcc 1050

 tgcattcgta actgaagaga taagtaaatg tcagaggtta agataaatct 1100

 ttttcttttt ttacctgtcc atatttacaa acattctgcg ttccgtacat 1150

 agacgcctgg ataagaaccc ctgtgcaaga atgactttgg tgctacttta 1200

 aaaaaagtgg ttggggaaga cctcatagga aatgacatca ataatagatt 1250

 gcatgataac ctatactagt tcttactgtt accaatttaa attctaactg 1300

 cttaaaagct aacacggtcc ttcccttttt ttgagcacct gatttgaagt 1350

 actttgagta ggcctcaagt gtcgtatgca agtactaatc tagggggtgt 1400

 gcctttttca aaagtgattt ttggagaaga taggatgtag tattatagca 1450

 aggaaaattc agcatctggg atgatcattt ccttctgatt agagaaattt 1500

 accttgttaa tattctgttc acccaaccct tctaccctca gtgttgacca 1550

 atactggaaa aaatttaggg ctttggagtg aaattttaaa agttcaaaac 1600

 cttgatctat taattagttt gcttaccttg aggaagttgc ttatcttaat 1650

 cttctatttg aacttcaagt acaaaaaccc tactcacgga cttaactgtg 1700

 accattaaat gagataacca aaaggctgaa gatgatagtg agttgatttt 1750

 accttttttc tacatacaga tgtttcagtt ctttcattag tggttgaagg 1800

 tctgcgttct ttttctccct ccactccctc cttgactacc cccagaatga 1850

 gctttgatgg tctctactgg gcctttgggg gggatacatt atcctgttgt 1900

 ttttgttctg ttacttatat ataatactca tggatttatt tctacttctc 1950

 ttccattttc taatttataa taacatgtgc atcttgtttt ccctgccaaa 2000

 ctaaatttcg tgagggggta catactgcac agtttttttt gtcacatact 2050

 gcttatgaca catgaatatg cagagcttgt caagctcttt aattaagttt 2100

 aaaatgctaa ttgagtgaat caaaacttaa ccattatggt taggctaaaa 2150

 atgtcagctt gtgtttatat agtgcttacc tcagtattgg aaatgccatg 2200

 agtttagtat cagaaggaca ttattactag tgcattttaa agtgatacca 2250

 gtcatagttg caaaagaaag tacacaatgg gaaatggaag agaaatgtag 2300

 ggaatcaaaa caactagttt tttcctttat aacggaagtt ttataattca 2350

 tcttttatgt aagtgtaatt ctcattaaaa ataccctaaa gcttaaagtt 2400

 tgcaaggctg cccagcctaa cccacaacag tttgatgctg ccccctagcg 2450

 tttgattccc ttcacctttt gctaaaataa ggtaatgttt aaattacaat 2500

 tagatttact tactgctgta aatctggtct attttagttt cctctgggta 2550

 gttagtgttg ctaataagat ggacgtaagt gtttttgaac tggtgaattc 2600

 tgattgcttt tagcccccag ttttccaaat aggggtgaat tttgggtaga 2650

 gatagaacaa tcaccaagtt accttgctcc aaaaaagaaa tttacgtatg 2700

 ggattgtttt caaagcggga agttagctgt gtaaataaca acaattttat 2750

 atatttaatc tgggcttctc cttatcttga atgatataaa aatctacttt 2800

 ctagattaat ttagttccat ataactttgt attgctttga ctgtactgat 2850

 aataaagttt gaaagtgtta aaaaaaaatc tatgtcgggt gcggagaaag 2900

 aggtaatgaa atggcaggaa ttcgatatca agctt 2935

<210> 4375
<211> 49
<212> PRT
<213> Homo sapien

<400> 4375
 Thr Ala Leu Phe Arg Lys Ala Leu Arg Trp Arg Ala Met Trp Gly
   1               5                  10                  15

 Ala Ala Gly Gly Ser Arg Arg Gly Thr Phe Ala His Arg Leu Ser
                  20                  25                  30

 Gly Ser Gly Asn Leu Leu Asn Ser Leu Pro Leu Leu Gly Ser Leu
                  35                  40                  45

 Glu Arg Pro Ser


<210> 4376
<211> 2857
<212> DNA
<213> Homo sapien

<400> 4376
 cctcaaccaa atgcaatttt ttgtgtgtgt ttgaaagcta atttgagaaa 50

 atttcatagg ttacatttcc tgcagcctat ctttatccac agaaagtgtt 100

 ttcttttttt taaatcaaga cttttaaaac tggatttcct cccatcactg 150

 ttttttgaag gtcctccaag tccgtgttaa ggtaaatatc tgttttcttc 200

 ctgatgtcac agcctgagca tactctgtgc attaggaaga cctgagtgca 250

 tttcccacca ttgtcctttc cacattatgt tgtagctggc tggctgtcag 300

 gcgactacaa gactgagggt cttgtgcctt atagatcttt gtatccccca 350

 tggctgacac atagtaggta ctcagtaaat ggttttataa tgaatcagtg 400

 aacattttgc ttctatagaa gtgtaccttc tttgtttcta tattatgaaa 450

 cctctttatt agaatttgtg attgattctg acagtgtata gatttacctt 500

 atattgtctt tattttccat gagctactaa gtcattagag atactctgaa 550

 gcatagttag tttaggaaat cacttcatat tgattgtatt agaattatct 600

 tggaattgaa gatatatccc tagagcaggg gaccccaacc cccaggccat 650

 gggccacaca gcaggaagag gtgagtggtg ggccattgag gagcttcatc 700

 tgtatttatg gctacttccc atcactcgaa ttaccacctg aactccacct 750

 cttgtcagct cagtggcagc attagattct catagaagca caaatcctat 800

 tgtgaactct gcatgcaagg gatctaggct atgcgctcct tatgagaatc 850

 taatgcctga tgacctgagg tggaacagtt tcatcctgaa accacccttc 900

 accctgcagt ctgtggaaaa attgtcttcc acaaaactgg tccctggtgc 950

 caaaaatgtt ggggaccgct gctctagaga gaggtcatga tatcatacca 1000

 accaaatgga aatgacaaat gttttatgtc aagtgttaat tgcagaaata 1050

 aatctttttt tttttttttt ggtagaaaac aaagaggcat actctgattt 1100

 ttatactctg tttttgcagg tgctcttttc tttgaatgga gatttgatga 1150

 gcaagtggtt aggatgcagg gagagctact atgggtgata ttttccttgt 1200

 ttaggagctg tgagttaaaa ttgtatcctt tctggtttat ctaaggaaag 1250

 tcaaatcttg acagaaaaca tttttccttg gaaggtcaac tctcagacat 1300

 tgtattttgg tttccctcag tcctcataac ttccttcttg ctgaacatat 1350

 tttattctct tttcagagaa ggaaaataaa aaggattcta aaagtttgat 1400

 gcattggaaa aatttccttg aggcatttag caacacatag aaaatgggct 1450

 ttgattcttt tccaaaactt ttagccatag ggtcttttat agacagggat 1500

 agtaaaatga aaattgagaa atataagatg aaaaggaatg gtaaaaatat 1550

 cttttagggg gcttttaatt ggtgatctga aatcttggga gaagctgttc 1600

 ttttcaggcc tgaggtgctc ttgactgtcg cctgcgcact gtgtaccccg 1650

 agcaacattc taagggtgtg ctttcgcctt ggctaactcc tttgacctca 1700

 ttcttcatat agtagtctag gaaaaagttg caggtaattt aaactgtcta 1750

 gtggtacata gtaactgaat ttctattcct atgagaaatg agaattattt 1800

 atttgccatc aacacatttt atactttgca tctccaaatt tattgcagcg 1850

 agacttgtcc attgtgaaag ttagagaaca ttatgtttgt atcatttctt 1900

 tcataaaacc tcaagagcat ttttaagccc ttttcatcag acccagtgaa 1950

 aactaaggat agatgtttaa aaactggagg tctcctgata aggagaacac 2000

 aatccaccat tgtcatttaa gtaataagac aggaaattga ccttgacgct 2050

 ttcttgttaa atagatttaa caggaacatc tgcacatctt ttttccttgt 2100

 gcactatttg tttaattgca gtggattaat acagcaagag tgccacatta 2150

 taactaggca attatccatt cttcaagact tagttattgt cacactaatt 2200

 gatcgtttaa ggcataagat ggtctagcat taggaacatg tgaagctaat 2250

 ctgctcaaaa agatcaacaa attaatattg ttgctgatat ttgcataatt 2300

 ggctgcaatt atttaatgtt taattgggtt gatcaaatga gattcagcaa 2350

 ttcacaagtg cattaatata aacagaactg gtggcactta aaatgataat 2400

 gattaactta tattgcatgt tctcttcctt tcactttttt cagtgtctac 2450

 atttcagacc gagtttgtca gcctttttga aaacacatca gtagaaacca 2500

 agattttaaa atgaagtgtc aagacgaagg caaaacctga gcagttccta 2550

 aaaagatttg ctgttagaaa ttttctttgt ggcagtcatt tattaaggat 2600

 tcaactcgtg atacaccaaa agaagagttg acttcagaga tgtgttccat 2650

 gctctctagc acaggaatga ataaatttat aacacctgct ttagcctttg 2700

 ttttcaaaag cacaaaggaa aagtgaaagg gaaagagaaa caagtgaccg 2750

 agaagtcttg ttaaggaatc aggttttttc tacctggtaa acattctcta 2800

 ttcttttctc aaaagattgt tgtaagaaaa aatgtaagac aaaaaaaaaa 2850

 aaaaaaa 2857

<210> 4377
<211> 59
<212> PRT
<213> Homo sapien

<400> 4377
 Pro Gln Pro Asn Ala Ile Phe Cys Val Cys Leu Lys Ala Asn Leu
   1               5                  10                  15

 Arg Lys Phe His Arg Leu His Phe Leu Gln Pro Ile Phe Ile His
                  20                  25                  30

 Arg Lys Cys Phe Leu Phe Phe Lys Ser Arg Leu Leu Lys Leu Asp
                  35                  40                  45

 Phe Leu Pro Ser Leu Phe Phe Glu Gly Pro Pro Ser Pro Cys
                  50                  55

<210> 4378
<211> 1752
<212> DNA
<213> Homo sapien

<400> 4378
 cgcctcaccc tcccacagtg ctggaattat aggtatgagc cactgtcccc 50

 ggccagattt ttttaaaagt aggtatcttg tgggatttat gttctgagag 100

 atacacctaa ggaaatgctg ccctacagtg tttttgctag ttcatactca 150

 ttacaaaggt ttcttgttgt tgggtgcccc tctagccagt ggtagtaaaa 200

 tgggaagaga caggtcaaga ctcccttgga ccatggcatt gagagaggga 250

 tggctgtcgg catagatatg ttggttattt aggcatttgt gagggaggcc 300

 cctggctctt ccagcctgtt tccttaggat cccagttggc cgggaacagc 350

 tgtacaaggg tctgctgaac tggtggtttc agcagactac ccagttccta 400

 agcatccatg agacagaggg aaccaacttg tatttccaga acaattttcc 450

 aaaccttttc tggctgtact ttaaaagtgc caaaaaggca atgggtgttt 500

 atgacactaa agtcacatac aagctagtat gatacataca tcatagaaag 550

 cttatagttg ctcagtgaca aagcaaagga agtttaatat tttccagttt 600

 tgttcattac cgaagacagt ctacggttca tagttttcac taaattctaa 650

 gcagattcta tatcctaaaa catttaaacc tcactaggcc tgcaattttg 700

 agagggttag ctaaatatgt ttggtatcac ttcagagtct aaaaccagat 750

 tactaatcgt gtgtaaggag gcattttgtg tgtctttgca atgtatacaa 800

 ttggattatt tggaacacca ttttgaatgt gtatttgaga gaaagctcgc 850

 ctgtgggttt tgagttgtgg tgtaatggtg aacatgtagc cacgtgaaag 900

 gccgttggat ctttgttctg attcttcagt cgtcttcttg caaattcaga 950

 gaaatgtctt ttaatcattt cgtttacata tcccagatcc ttggaaatca 1000

 tgaaaaataa cttgccagag tttgcatcag ccctcagtaa gtcatgaacc 1050

 atagagaagg tcatggggcc atttattctt tggaccactg gctacttctg 1100

 aagttctggc ttccttctct ctaggaggag tcgtgtattc aagcttttaa 1150

 gttaaatgca taaaaatgag ttttacttct cttctgactt gatttttaat 1200

 tttatgaaat gggaaataat gtttttccat ttttctgttc attttgaagt 1250

 gggaatttga ggtgtttgta atgtcatgtt actgttctga aagattgaca 1300

 gtaaagaaga caagaaatat atgtatgtag tatgcatatt agttttgtcc 1350

 caccaagcct atctttgaat ggcaaacatt ttaaaaacat ctgttctagt 1400

 tgcacaacta ctctagcttc tttataaagt aaacaatctt aaagtaagca 1450

 atgttggcca taatttcaat attctagcct tgccgagtgt gaatatattt 1500

 tactcagaga ctatgtacaa atacactaaa gtggtgatgg tgatcaatat 1550

 tgtaaagaat ttattctgat aaatgagaaa ctggatataa tgtcaaaata 1600

 gctattttct caataaaaat ctcaaatctc ctgactgctt atgaattctc 1650

 gatttaatgt tatttattct ttgaggtaaa tcttttcatc gcgaagaatt 1700

 ttttgctggt tgaatgtggt tgttcagggc tgggactgag ctatagacat 1750

 ag 1752

<210> 4379
<211> 31
<212> PRT
<213> Homo sapien

<400> 4379
 Ala Ser Pro Ser His Ser Ala Gly Ile Ile Gly Met Ser His Cys
   1               5                  10                  15

 Pro Arg Pro Asp Phe Phe Lys Ser Arg Tyr Leu Val Gly Phe Met
                  20                  25                  30

 Phe


<210> 4380
<211> 3241
<212> DNA
<213> Homo sapien

<400> 4380
 ttccagctca cttgcggtgg cagcacaact tagggaaata ataccatcca 50

 gtgctttgcc taatggcaca gttcagcata tcctcatgcc agatgatgaa 100

 ggtgaaggtg aattgtgttg gaaaaaagta gacttagggg acatgaagaa 150

 tgtggatgtc ttatctttca gtcatgctcc ttcattcaat tttctttcta 200

 attcatgttg gtctaaacca aaggaagata aagcagtaga tacatcagat 250

 ttggaagttg cagaagatcc tatgggcctc caaggaatag atctgatcac 300

 agcagcattg cttttttgtc taggagattc tccaggaggg aggggtatat 350

 ctgatagccg catggctgat atttatcaca ttgacgttgg gactcagact 400

 ttttcacttc catctgcaat attagctaca agtacaatgg ttggggagat 450

 agcttcagct tcagcttgtg atcatgccaa tccacagctt tcaaatccaa 500

 gtccgtttca gacacttggg ctggatttag tattggaatg tgtcgctagg 550

 taccaaccca agcagcgttc aatgtttacc tttgtgtgtg gacagttatt 600

 tagaaggaaa gaattttctt cccactttaa gaatgtgcat ggtgacattc 650

 atgctggact caatggctgg atggaacaga ggtgcccttt agcttactat 700

 ggttgtacct attctcagcg tagattttgt ccatcaatac aaggagcaaa 750

 gattatacat gaccgccatt tgaggtcatt tggagttcag ccatgtgtat 800

 ctacagtatt agtggagcct gctagaaact gtgtgttggg attacataat 850

 gaccatctaa gtagtcttcc ttttgaggtc ctgcagcata ttgcaggctt 900

 tctcgatggc ttcagcttat gtcagctctc atgtgtatcc aagttaatga 950

 gggatgtgtg tggcagcctg cttcagtctc gtggcatggt catactgcag 1000

 tgggggaaaa ggaagtatcc agaaggaaat tcatcatggc agataaaaga 1050

 aaaggtatgg cgatttagta ctgcattttg ttctgttaat gaatggaaat 1100

 ttgctgacat cctaagcatg gcagaccact tgaagaaatg cagttacaat 1150

 gttgtcgaga aacgggagga agcaatccct ttgccatgta tgtgtgtgac 1200

 acgagaactc actaaagaag gacgttcact acgctcagtt ttaaaacctg 1250

 tactttaaaa gttgtaatat tactagcaca tatatgcaag cacctagtat 1300

 aatttctttg taatatgtga aactttatta atgtattaaa tattacaact 1350

 agctaaattt attgtcactg tgtatataat gttttgaagt gacatctatt 1400

 tttataaagt actgtttagt tggaaaaagt tgccttaatg tttgaaatgt 1450

 gtgaaatttt tggaacttgc tggacagggt gatttaattt ttagctacat 1500

 aattttaaga attagtattt tcagtggtgt gcatattttg gttcttaaat 1550

 ttttgcttct taaactaaaa aaatcctgac caatttattt gttgttttct 1600

 gtgggttgcg acccatgcaa tcaaaaagca aaattttgat tgagattttt 1650

 tacagcatag gtttttcata taaaaatatt ctgaatttgt taagcactgc 1700

 cataatatca ttataatgtt tttgtctttt agtgcttccc tatacaattg 1750

 ttaatgcaca aatgatctct aatatatact tacatacgta aaatcataaa 1800

 gtttggtaat gcagtttatc gttttaaaaa taatccacaa agatgttttt 1850

 atctcacata cttacaactc aacacacaga gtgaccatgt gcagctttct 1900

 tttttgttag atgccacatc cgaagactca tcgcagtgtg ttatatgaca 1950

 ggacaaagca aaaacaaaca aaaagcaagc ctgtgaatat aatttaattt 2000

 gaaactgctc ctggtattat atatttgcta gttatctaat gttttaaaag 2050

 aaaatatacc tcatttaggt ttgaattggg cgtattgtgt aaatttcaaa 2100

 tattcagaat gcaaagggct tgactattaa atgtttgcct ttgatgttta 2150

 taaacattac aactatgttg ttttaagaca tttaaaaacg tgaaatttgt 2200

 tatctttgta aaatgacaat catgtagaaa cctgtcttgg ttgacaatct 2250

 ctttgaaaca tttccgagtt aatttcccat aggcttcacc accaagaaag 2300

 taagaattgc atctttacat aatgatcaag gtataatgga aaaatatacc 2350

 tattcttgaa gtagtttatt atagttttca aattgattta taccattatt 2400

 aacctgatgt ggtctgctta aaaaatgaat atatcagtat ttagaaataa 2450

 attgcaaagg tgggaatata tacttaaata atttgtctta agtaaattag 2500

 catttggtag tctgaaatgg tgacagatta cttgttaaaa ttgtgaaaac 2550

 tctgttgtgt cctctcttcc tacatttgtc cctgagagta ctccacgatt 2600

 actaggttct tgattccctt atatggcaat caggcagagg cgttccttaa 2650

 gcattagaga gttctgaagc ttaagatttg ttttggttgg atgaagtcct 2700

 tagtacagtt gaaaaacaga gcattaaaga ctaatcaatt gttttgcctc 2750

 accagtcatt ttaaatagta gaatacttat ttctcagtgc ttaaaatttc 2800

 tttttcaact gtgagattga ataaacagtc tctatttctg tggaaaaaac 2850

 aacagaaaag agatattaaa taccataaaa tgtaactctg ccttttaaag 2900

 ttttgctgaa gaatgtgtct gtggttagga tagcacaagc attaactttt 2950

 gttttatagt tatgcttttt aaaattcatt gtttttaaat ttagacttct 3000

 tatttccaca ctggattatg agatacttaa caatttttcc accttatatt 3050

 tcttttacac attttgctgt tctctttttt gttattgtta tgccaccata 3100

 ccattttgtt aaaatgtttt ctttgtgaaa catttgttca agttctaata 3150

 aaattaatgt tttcccttaa catggctcaa taacttaaaa acgttcattt 3200

 aaataaaatt ttaatacttg tttgacaaaa aaaaaaaaaa a 3241

<210> 4381
<211> 390
<212> PRT
<213> Homo sapien

<400> 4381
 Met Pro Asp Asp Glu Gly Glu Gly Glu Leu Cys Trp Lys Lys Val
   1               5                  10                  15

 Asp Leu Gly Asp Met Lys Asn Val Asp Val Leu Ser Phe Ser His
                  20                  25                  30

 Ala Pro Ser Phe Asn Phe Leu Ser Asn Ser Cys Trp Ser Lys Pro
                  35                  40                  45

 Lys Glu Asp Lys Ala Val Asp Thr Ser Asp Leu Glu Val Ala Glu
                  50                  55                  60

 Asp Pro Met Gly Leu Gln Gly Ile Asp Leu Ile Thr Ala Ala Leu
                  65                  70                  75

 Leu Phe Cys Leu Gly Asp Ser Pro Gly Gly Arg Gly Ile Ser Asp
                  80                  85                  90

 Ser Arg Met Ala Asp Ile Tyr His Ile Asp Val Gly Thr Gln Thr
                  95                 100                 105

 Phe Ser Leu Pro Ser Ala Ile Leu Ala Thr Ser Thr Met Val Gly
                 110                 115                 120

 Glu Ile Ala Ser Ala Ser Ala Cys Asp His Ala Asn Pro Gln Leu
                 125                 130                 135

 Ser Asn Pro Ser Pro Phe Gln Thr Leu Gly Leu Asp Leu Val Leu
                 140                 145                 150

 Glu Cys Val Ala Arg Tyr Gln Pro Lys Gln Arg Ser Met Phe Thr
                 155                 160                 165

 Phe Val Cys Gly Gln Leu Phe Arg Arg Lys Glu Phe Ser Ser His
                 170                 175                 180

 Phe Lys Asn Val His Gly Asp Ile His Ala Gly Leu Asn Gly Trp
                 185                 190                 195

 Met Glu Gln Arg Cys Pro Leu Ala Tyr Tyr Gly Cys Thr Tyr Ser
                 200                 205                 210

 Gln Arg Arg Phe Cys Pro Ser Ile Gln Gly Ala Lys Ile Ile His
                 215                 220                 225

 Asp Arg His Leu Arg Ser Phe Gly Val Gln Pro Cys Val Ser Thr
                 230                 235                 240

 Val Leu Val Glu Pro Ala Arg Asn Cys Val Leu Gly Leu His Asn
                 245                 250                 255

 Asp His Leu Ser Ser Leu Pro Phe Glu Val Leu Gln His Ile Ala
                 260                 265                 270

 Gly Phe Leu Asp Gly Phe Ser Leu Cys Gln Leu Ser Cys Val Ser
                 275                 280                 285

 Lys Leu Met Arg Asp Val Cys Gly Ser Leu Leu Gln Ser Arg Gly
                 290                 295                 300

 Met Val Ile Leu Gln Trp Gly Lys Arg Lys Tyr Pro Glu Gly Asn
                 305                 310                 315

 Ser Ser Trp Gln Ile Lys Glu Lys Val Trp Arg Phe Ser Thr Ala
                 320                 325                 330

 Phe Cys Ser Val Asn Glu Trp Lys Phe Ala Asp Ile Leu Ser Met
                 335                 340                 345

 Ala Asp His Leu Lys Lys Cys Ser Tyr Asn Val Val Glu Lys Arg
                 350                 355                 360

 Glu Glu Ala Ile Pro Leu Pro Cys Met Cys Val Thr Arg Glu Leu
                 365                 370                 375

 Thr Lys Glu Gly Arg Ser Leu Arg Ser Val Leu Lys Pro Val Leu
                 380                 385                 390

<210> 4382
<211> 2331
<212> DNA
<213> Homo sapien

<400> 4382
 gtcaccttgt aactcatctc tttttattgt aagtttatta aaaatgaaga 50

 ggacaacaat gagaaggaac ataaagggtt agctagcact gtctcctggt 100

 gcatggggct gtgcagatgt cccggccact tcttccttca tacttccctt 150

 agagaacttg ctctgctaca agcagtgggc ttggactaaa agtgattaaa 200

 ataccacagg cataaggaga aaaggagtat atgtagtagt aataattact 250

 agtataaatt attttcttca catgctatga gtaataatat taaaaaactc 300

 attttaccat taagattcct tatgctgaag ctcttccatt tagaatactg 350

 tcaatgtcat ttactggtat gaactaaagt cccccttctt ttccactcac 400

 tgggaacctt agtaaaacac cagcatatct tacctctctt tctgactggc 450

 cgatgcttcc agagactgaa tgttgggaaa acctagtagc caaacaattc 500

 taggacagaa taacattttt atatttggtt ccaccatctt attacattta 550

 gttatagttt taaaaaagaa attcaagccc attaaaatat gtctggtcaa 600

 tgaaatgctt ccttttattg tgttgtgcta ttgtactttg tttttcaaaa 650

 cattgtaaaa atagtatctt tggtttagta ttttggatta tatattataa 700

 tctgaggagt gttttgctta tgtagaatcc agatatattt ctgttaccta 750

 ggagatgtta cttacatatg taatactgta tcctgcacgt ggaaatattc 800

 agaattgtag atagcataac tctccctgct cctattcttt tgagcctagg 850

 tataattttt tttttttttt tagaaaaaga catatttagc tttaatttct 900

 atttatgcta aacatattta taagtagtct gtcaatataa taccaactat 950

 ttttattttt acataattca attatttcat ttgacatgtc tggcagactc 1000

 aagacattaa gtaaaaaatt ggaactatga tttttctttg tcatttttta 1050

 aaaaagaatt attttattaa cctgctggca tataatctgg agttcttttc 1100

 acaaccttac tttttctgat ttgctttatt gaatgattga atactcattt 1150

 ctttctaaaa atatgttgta aattctccct tggcaagatt tctccctatg 1200

 agggtagtta ttatttgagt ctgccaagtg gttaccatgg ggcaaggtgc 1250

 catgatgtat tcttgggtgc attggttttt tgcgcattgt aaatttaaga 1300

 cacttatagt aagtggactc attcatagat gagtttcaga accttttacg 1350

 ttctcggtag aggcttctgt cggacaggca gaagagtgta ttcctcactt 1400

 ttttttttgt cttcaaattc cagtaaggca tagcactttt aagaaattag 1450

 aatttttcta tcatctatgc aaatgatatt tatgttaata ttaaatatct 1500

 tatgttacac tgggagtaat ttgaggtgca attattttta ttactacttt 1550

 gaatagagga ccattatcct tctttcttca gaaaactaag aagtaagtgt 1600

 aacttttaaa gtaagtatat atcagtgaga gtaggcttgt tttacaacta 1650

 tttctagcca gtgagttgtg ttttcatgtc tcatcaaaag acaataccac 1700

 attgcatcat tttacaaaat atgttgtcat tttcatttca gttgtaacat 1750

 aggaaaatag atatttccta gatgatttct gagtttctta ctgcaaagaa 1800

 cagttataaa ttggtataca tgtgtctctg taatagggat aatattgata 1850

 tatctgttgc tacatattta agaatcattc tatcttatgt tgtcttgagg 1900

 ccaagattta ccacgtttgc ccagtgtatt gaattggtgg tagaaggtag 1950

 ttccatgttc catttgtaga tctttaagat tttatctttg ataactttaa 2000

 tagaatgtgg ctcagttctg gtccttcaag cctgtatggt ttggattttc 2050

 agtaggggac agttgatgtg gagtcaatct ctttggtaca caggaagctt 2100

 tataaaattt cattcacgaa tctcttattt tgggaagctg ttttgcatat 2150

 gagaagaaca ctgttgaaat aaggaactaa agctttatat attgatcaag 2200

 gtgattctga aagttttaat ttttaatgtt gtaatgttat gttattgtta 2250

 attgtacttt attatgtatt caatagaaaa tcatgattta ttaataaaag 2300

 cttaaattct catctaaaaa aaaaaccact a 2331

<210> 4383
<211> 26
<212> PRT
<213> Homo sapien

<400> 4383
 Ser Pro Cys Asn Ser Ser Leu Phe Ile Val Ser Leu Leu Lys Met
   1               5                  10                  15

 Lys Arg Thr Thr Met Arg Arg Asn Ile Lys Gly
                  20                  25

<210> 4384
<211> 4881
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3603-3790
<223> Unknown base

<400> 4384
 ggataattcc attcttaaag ttttgatcag tatgcaactg atgtctggtg 50

 acccatgttt taaaacgcct ccctccactt caatgtctat accaattgct 100

 ggtgaatctg aatctttgca agaagataga aaaggtggag agactctcaa 150

 agtgcatctt ggaatagcag atctttcagc aaagagtgcc tctgttccag 200

 acgaacttgg tgcctgtgga cattctagaa catcaagcta tgcaagtcag 250

 cagtcaaaag tatcagggta tagcacgtgt cactcccggt catctagttt 300

 ctctgagctc tgccacagga gaaatacctc agtgggaagc acatcaacag 350

 gagttgaaag tattctagag ccatgtgatg aaattgagca gaaaatcgct 400

 gagccaaatc ttgatacagc tgataaagaa gatacagctt cagaaaaact 450

 cagcagatgc ccagtgaaac aagattctgt agaatctcag ctgaagcgag 500

 ttgatgacac cagggtggat gcagatgaca ttgtagagaa aatattacaa 550

 agtcaagact tcagcctaga ttccagtgcg gaagaagaag gactaaggct 600

 atttgtgggt cctgggggaa gtacaacctt tggcagtcat catcttccaa 650

 atagggtggg gtctggagct tatgaacaag ttgtgatcaa acgctagaag 700

 tcaagtcggt gaaaacattt ccttgtggat ttaagatgtg agtagttgat 750

 gtatcaaggc attttattca agcacttaat agaaaatgaa cctcaactat 800

 caagaggaaa gccaatgctg gtttcttctc tggaaggacc caccgccatc 850

 ctgtaccagc caccaaaggg gaacatctac atggcagtct ccaggcactg 900

 tgccactgtg tgccttggaa gcacctggct tctgtggtca ctgcacatca 950

 taatgaaaag cctgcttttt ctttcagaac accccagcgg agaaaacagc 1000

 attatataca tcggagtatc attttaggat tcaagtgtaa aaatctgtga 1050

 tcaagaggct caatagattt gggctctatg gttggttttt ttagtttgag 1100

 agacagtaca tgaatataac ttaaacccta tagattttgt caagatagtt 1150

 gtaattcctg ttctggaaat cttccctatt acactaccta cagcattgta 1200

 taaagtgtgg gtgttcatgc tttgggaaaa tgttagacta caatttaaac 1250

 atgtgatgtg cttattcata attctcagtg tatcagtcat aaatgaaata 1300

 acaagtgcat ttaagtcaga gatacgtgaa tggatgtaat gccgttatgc 1350

 agtatatatt gttaattgtc attaatatta gatgagctgc agaaccaccc 1400

 ccaagcacta cataaaagac tcaaaataag tttaacactt actgtgttgg 1450

 gcaccctaac agaagagcta tcttaactca ttgaatatta agatctgctg 1500

 gtttcaggag tcaaaatgta gaaaaagagg agaattgtaa tatggtcaga 1550

 aacagagaag ccttttctat gtaaattcag acttatctga ggctaacagt 1600

 tttccgaagt ggtggtgggt agcagcatga cagctgcttg ccatgactga 1650

 tgcagactac taggtttcca ttttagctct ctgtaggtac tgttttcttc 1700

 cccactgtgt cgaaagtgat ttgttttgaa gcaagagtag aatataacat 1750

 ctatcaaata tagcttttaa aataagaata cctggtctgg atccagttga 1800

 gcagcacagc agataaacct tagagttttt ctgttcttac atgacggttt 1850

 ccatgtggaa agatctaaac tttcttggaa tcactattag tgaagaaaaa 1900

 tgtagaatct gtataaccag taattcccca attcttactt tcaaagtcat 1950

 atccaagaaa gacaatatgt cagaatagaa tgactttggt ctaggtgttt 2000

 tcacgttggc aaaaataagg aggaaattat attattttaa tatccaaatt 2050

 taaaggtttg gaaaattttg aatagttaat attagaactt atgttgctgt 2100

 tttttatatt tcaaggattg agtattctgc attaatccaa tactattcca 2150

 acaaagagat tctggaagtt tttaaaaaat gataccctgt tttatatttt 2200

 gaatgtagag agactctgag agagagaatg ttctgagtta tactttttat 2250

 tttttaagat ttatttttaa gaataaaaca ttgacctgaa cattttagcc 2300

 taaccaaggg acttaagtgg taaagacttg cattatgtct tcatgtgaac 2350

 tgatccgttc attatatatt atgggaaaaa tcaaagaaag ttttttatag 2400

 agatatgaag atattattta gagagatatt tattatgaca ttttttaaaa 2450

 acatattttt ctattttcaa aatattattt ctaggctata tttttattgg 2500

 tgctgtgcaa atgattttgc agttttgaaa atgataaaac tagattgtaa 2550

 gtggggttca gtgaggacat tcatcagaca cgtaagaggt gctgcaatca 2600

 gggtgatgcc catcttactc atccttggct gcccttggtc cgacacctct 2650

 ctatacaaga ctggttctca gtattttaaa tggtacagaa ttctttttaa 2700

 aaagtagaga gattttgaaa agcataaaaa tcatgccttt ataatcttag 2750

 cagccatcag atacaccttg atttatgtag tagtaaatat aacaaatatt 2800

 ttaataaata gaaacactga taaggaagaa aaaagaacta atgtctatgt 2850

 cttctgtagt cagcaaaagt ctggatccat tttctatttt gtgttccatt 2900

 ggcacacttt gtgttcaaat ttcagtgcag tcctttcaaa atactcgcta 2950

 agggttgcct aagtgtctgc cttactttct gattgtcctt ttctgagagc 3000

 atggttaaga acatcttaac catatagctg ttgaaaaaat ctgtttatta 3050

 aataacaagt tcacttctgt ttatgttttg agtttagaaa atttgacttg 3100

 aaaatttaga ttattaataa atttattttt aaatattaaa gtcaaatttc 3150

 aaatcaccca gtgttgaaga atttgcagat gtatacaata ctttttctaa 3200

 ttatgtcttt tctatctcca tgcctggctt tttctaatta tatcctagag 3250

 aaaaagacta atggtatttc aaagctgtgt atttgtgacg agataaagaa 3300

 gagtcttaaa catcttgttt gggagaatgc acaggccagt caggagaccc 3350

 acctcctcct gtgccctgag ctgctgagac ccgacagatc atgaaggcta 3400

 gtaaagggca gagaaggccc tgagccatca gtttacactc gaattgttga 3450

 ctcccctttg tggtgttttt gaaggctgct tataccaaca gctaatgtgg 3500

 attagtgctt atgatcttga aaaagtcttg accaagaatc ctaaactcca 3550

 ccactcctcc cattccagct taacactatc agaataatat ccaaattcca 3600

 gannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3650

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3700

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn tagtttcttt 3800

 tctgtatgct ttttttacaa aactgtgagc cacagaggtt gaccacttag 3850

 ccaatttgtt gctagaaggg agaaaaaaat ctccaactag cctccagaca 3900

 aaacatactc aaattcaaac agcagttagt tttaattaac atacagaagt 3950

 aattttagac tttcagattt ctatgctgac tagaacactt tgcaggctga 4000

 agctgacatt attaccaaat acttcattta agtacatact ctgaagtgtc 4050

 aggcttccag tatatatagc aacgctctga gagacaaact gggctcatat 4100

 gacggggttg cattttattt tcttaacagg tctttaaatt gggcagttct 4150

 gaaattctgt ttggtcagtt ctagatggta cgtcatgtga atgcaaccaa 4200

 gcactgtagt tgaaattgtg ttatgccact actcatatgt tgtcttaggt 4250

 actacgcata atgttaatag ctgagatgtt aaagaatttg aagtctaaaa 4300

 tataaaagat gaatataccc atattaatcc tatgttaaga tgctctggaa 4350

 ataaaggcct tattccctta cacatgcgat ttttgtaaga taatatatac 4400

 acagtatatt ttaaatgttt gtgtgggtgg tctgtgtagt tactccccat 4450

 acaacaaagc tgacaaaatt tttaatttac acaatgtatt ctgcattttc 4500

 aaatgtttat gttgtgtata tagcaaagaa attatcttac tgatatgcgt 4550

 tgaccaaatc ccatggagaa aagacatctc atttgaggtt ccccttcctc 4600

 tcatgtgttt gattttttgg aaggtgatac agtatgtggg taaccatgca 4650

 aatgtttatg aataacttta ctgaagtgat tccatccgta ttctgttcta 4700

 atacttggag aatgaccttc atatttatat attttatttc tttgtttcaa 4750

 ctatccagtg ataattcagg aaatgtttcc tttttttttt ttttttacaa 4800

 aaacttttta tttgtaaaat gtttgtaata atgtaaaggt gaacatgttc 4850

 aataaaaatc atatattaaa agtttaaaaa a 4881

<210> 4385
<211> 231
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3603-3790
<223> Unknown amino acid

<400> 4385
 Asp Asn Ser Ile Leu Lys Val Leu Ile Ser Met Gln Leu Met Ser
   1               5                  10                  15

 Gly Asp Pro Cys Phe Lys Thr Pro Pro Ser Thr Ser Met Ser Ile
                  20                  25                  30

 Pro Ile Ala Gly Glu Ser Glu Ser Leu Gln Glu Asp Arg Lys Gly
                  35                  40                  45

 Gly Glu Thr Leu Lys Val His Leu Gly Ile Ala Asp Leu Ser Ala
                  50                  55                  60

 Lys Ser Ala Ser Val Pro Asp Glu Leu Gly Ala Cys Gly His Ser
                  65                  70                  75

 Arg Thr Ser Ser Tyr Ala Ser Gln Gln Ser Lys Val Ser Gly Tyr
                  80                  85                  90

 Ser Thr Cys His Ser Arg Ser Ser Ser Phe Ser Glu Leu Cys His
                  95                 100                 105

 Arg Arg Asn Thr Ser Val Gly Ser Thr Ser Thr Gly Val Glu Ser
                 110                 115                 120

 Ile Leu Glu Pro Cys Asp Glu Ile Glu Gln Lys Ile Ala Glu Pro
                 125                 130                 135

 Asn Leu Asp Thr Ala Asp Lys Glu Asp Thr Ala Ser Glu Lys Leu
                 140                 145                 150

 Ser Arg Cys Pro Val Lys Gln Asp Ser Val Glu Ser Gln Leu Lys
                 155                 160                 165

 Arg Val Asp Asp Thr Arg Val Asp Ala Asp Asp Ile Val Glu Lys
                 170                 175                 180

 Ile Leu Gln Ser Gln Asp Phe Ser Leu Asp Ser Ser Ala Glu Glu
                 185                 190                 195

 Glu Gly Leu Arg Leu Phe Val Gly Pro Gly Gly Ser Thr Thr Phe
                 200                 205                 210

 Gly Ser His His Leu Pro Asn Arg Val Gly Ser Gly Ala Tyr Glu
                 215                 220                 225

 Gln Val Val Ile Lys Arg
                 230

<210> 4386
<211> 5629
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 708-897
<223> Unknown base

<400> 4386
 cgaagatcca agtttctttc catctgcctg aagaactttc tttagcactt 50

 ctggtatagc agacctactg atgataattt ttcttttagt atatggtgat 100

 tagtttactt tttattcaac tgtgtctttt tttgaagtct tcttcattga 150

 aatatattgt tactaaatat agaattaatg gctttcttta agcacttcaa 200

 agataatcca ctgttttctg gactccgttg atacttaagt ctttattttt 250

 gtgtaattct ttttctttaa atgtgccatt tttcattttt ctctgactcc 300

 tacctactaa gatattttta cctaagtatt gagtcagttt tggttatgat 350

 gtgactcagt gtgtttttat ttatattgtt tggttgtttg aacttcttga 400

 atctgtaaat gttgtgcttt atgttaaatt tggggggatt tcagccattt 450

 aaaatataac ttttcagtct cttccccctg ggactccaat ttttacatat 500

 gtattagacc tattaatatt tttctatgga tacctgacat tctttttaaa 550

 tcttattttt ggtgtttttc actttgaaca acctaataat ttgtttccat 600

 ccatgtttac tcactgttta ttctattttt tcccaatctg ctcttaagcc 650

 tatcctgtga attttctttt taatttattt tattttttag ttccagatat 700

 tttctgcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnntcg 900

 ttgtgttgcc cagctgtctt gactcccaga ctcagcgtct tcctgcctcg 950

 cctcatgccc gcgccaacca gttctttatt tttaatatta tgttgtattt 1000

 gatgtgctat cctattcatt tagtataagc acatttttct ttatgtcttc 1050

 agcataatta tatgcttttt cagaatttta acatcaggac tgcttccagg 1100

 gtagctttat tgccctttgt cttaagtatg gattatagtt ttcattcttt 1150

 gtatgtcaag taattttgga ttgtaacttg aactttgaat atactgtaga 1200

 aactctgaat tctattttat tcttctaaaa caatatttct cagcttcagc 1250

 actactgaca ttttgaactg ggtcattttg tttgtgttgt tgtgtgtatt 1300

 ttgggagggt actgttctat atgcattgtg gggtactgag tattatcctt 1350

 tgtctccact cactacttac cagtagcata actctctctc ctccccacat 1400

 cccctgccaa aaaatgcctt cagtcctttc taagcgctct tttttatggt 1450

 gttggggcca aaatcatgca tctttactca ctctttctca ttgagagcta 1500

 tggctataaa gggtagtgat acttttactt atttattttt aaggcaagca 1550

 gttaacttag ctggattcaa actccaggct gcctcgtgtg ctgtgggaag 1600

 cagcctacgc tctattcagt tcttttcttt tcatattggt tgggttactt 1650

 tgagtctggc ctacatgatg ggcagtttag aggtcaacca aaggatttca 1700

 gcagaactta tacacagaat ttcattcagg cttcccgtgt ctgattggct 1750

 acagtgtggg aatttcctcc cacttttcag ccactactga ggatgccttt 1800

 cggcaaaatt ccttgaaatt ggaaacttac agggaaattc ctttcctcca 1850

 agagtgcgct ctcctccagt gttggcttgc ttttggttgt tctccgtggt 1900

 tttagatagc tgtctttata ttaattctgg agtttacagt tgatatctgt 1950

 tgggggctta gtttgataac atgtattctt ctattactag tagccagacc 2000

 tgtatgtctt acttgacctg atggagaaaa gtttcaactt atgagacaat 2050

 actgtgctag ctagttttac tgatttgtac tctaaagtac ccaagcctaa 2100

 aatagtagag ctgtctatcc cacatgaaac ttctctgatt ttcactgttt 2150

 tttataaaaa gtatacatgt tcacatttct gtaggttttt ttaagcatca 2200

 caatttttat aaactttcta tatttccaag gtctacctgc tttgtatttt 2250

 gcctagtgag agttttgtat tcatgtagga ataatctctt ggtgtgagta 2300

 tctattttcc actcatccaa aacagataga gcattgattt cactaagcgt 2350

 tatgttctag tttgctttgg tattattatt agaaatacct ggtgattaat 2400

 ttgagctaag tattcttctc taccctcatt cccagcatta tcacccgctt 2450

 ttaccacttc caaggggtgg aagcattctc cacaatgcat tttttcatgc 2500

 cagagaaaaa tctagaaaaa aatgaataaa acgaagaaat tctttcccct 2550

 tggtatctgt agctaacttg cctaagtgtt ctttcccaca gtttaagtct 2600

 tcagtccata gttcataagc aaaggggtgt agcgagctct gatcttgcca 2650

 gaagagagaa taagtgagct accccacggt ggacattctg gccatctgaa 2700

 atgagtcgat gcatgtggct tttgtctaaa ggctacaaat aaaatgtaac 2750

 cactttcttc tttgagtagt tgatatagca aatagttgaa acagaagttt 2800

 tgattggcaa atcaggatgt ggtagatact ttaacaaaga gtagaactat 2850

 taccagtttt atgtgttgct gtttgtatct ctttcacagt tttgataata 2900

 tcacatcctg gaaagtgaaa cagaaaatta ttattccatt ttaaatgact 2950

 aaatttgctt tcatggtatt tacagtgaaa gagtaaatta gaaagtgaat 3000

 ggatgactgt tcatgagaaa aagcagggta aaaagatttt atttaattaa 3050

 ttgaaaatat tagggtcaaa acataggctt atgttatgtt ttgtgaattg 3100

 tgctgtgttg tagacatttg atgagtccta acatagaatt gatctagctc 3150

 ttgaaatacc atttttgatt gagtataaat gggatatagg caccttacaa 3200

 cttcagaatt cgaggaagat gatgtgaatc ttccaatttt atctatttga 3250

 ttcaaatggt atgttttttc acatttctca taatttccac gtcaactccc 3300

 atgatgatca tgcaggaaag cagcatgatt gcacttcttg tagtgcatac 3350

 catcactaaa acatagttac tgtctttctg tggtcttaag aaaaattcag 3400

 aaacagcata ccaatgtaca tataagataa ataagcttat gtggtacagt 3450

 aagtgttctg ttctgagaaa taccttgatt cgtatcctaa tgtctgatgt 3500

 tattggtagt tctcaaactt ccccaattct gctttcatct aaattcatct 3550

 tatctatcta ttgttaaata atctatcagt ccatttttat ctatcatcta 3600

 tatatctgtc tttatcaatc attcgtctgt aatctatctg tgccgtttgg 3650

 cataagagac agaagggcat agcagtggaa actcaaagga gttacctcca 3700

 tgtgaatgga cagtggtgat ggtgatctgt gaggtggtga tgtatagaaa 3750

 gaaaaactag aagagagcat gccctaactc agggaccttg tccagcaggc 3800

 actctggcct tgttatactg tgcttgaata tgaaaaaaaa aaaaatcaaa 3850

 atagtgctga cattctttgt cttctgggtc tgagaaaact tagagtagat 3900

 atgatgactc tgccatttca gtcttttgta tttccacatt tagagctcag 3950

 ttttaattat gtagaattat ttctccagcc tgtgttaaac tagaccatgg 4000

 attggcaaac tttttttgta aattgccaaa tacacatttt cagttctgaa 4050

 agccttgtgg tctttgttgc agctaatcta ctctgctgtt gtgttatgaa 4100

 agcagccata ggtaatttat aattgaatga gtgcgctgtg cctttcttcc 4150

 aataaaactt tacaaaagca tcctgtgggc tggagtttac cctttgggaa 4200

 accagagcat tggctaaact ggaacctgaa aaaataatca catcaactca 4250

 gccacatggt aataatattt agagtattat ttcaacattt tcattttcat 4300

 aaaaattttt ttagctcttt tgccaaattc catctgtgag tgatacaaat 4350

 gactaccacg tgccattaac atcacctaaa cagtgcaaaa caagcatagt 4400

 agaagtaatt ggaatgatat aaaccccttg ctgtaatagt tatagttgat 4450

 aaattatgtt tcaaaattga acctatttct tccaaatttc atctataaag 4500

 ttccaaggag ttccaaaatc ttgcctgcct tcttttccca gttagcagta 4550

 ttgtctctga gcagccatgg tggtatccat cctccttgga caatgaattt 4600

 agcctatttt gacttcattt gagcagttgt aattgtttca ccacatcaga 4650

 gtaagattac tacatgccag agctattctt taactcagct tgtaaaaaca 4700

 tgatagcatc aacaatatac atagcaaatg aatgccatct ttaatccaat 4750

 taaatggttt ttacaaattt gctcttgttt gttgatgcta tctgcattgc 4800

 agtaattaaa ggtgaggtaa aaagaatgaa taaactgcca agttaaaatt 4850

 aaatttgggc aatttctctt ttgcagtaat gtatgtatat ttactcaaaa 4900

 catatgccaa atttagtgtt gaaaggctca ttcaaatcaa ttgggaaagc 4950

 acgtaaatga acaattcata aaagaaaagc attgcaaatg gccaagagca 5000

 tagaaaatgt gctcaatctt accagtcatt ataaggaaat aatgaaattt 5050

 gtgtatatat gaaatactta aaatatatat aaaataaaac aattatttgc 5100

 cttttttcac ctatcagatt aacagattat atgtgttaac aaggtgggga 5150

 gaatttacaa ctcctgatat gttaaaatct ttcaggaagg tagtagaaaa 5200

 tatatgtaag atggaaatta gcacttttga ccaacaattt tagttttaga 5250

 tatttaccta taaggatata ataggaggtg ttcaaagatg catgtaactc 5300

 aatgtagtat taattataat tgtaaaatag taaataacat ttttgtcaaa 5350

 tcataatgtt aggaaaatta gtgatggcac atttaaccaa ttgaattata 5400

 ttcagttctg aataccgtga tgcatgttca aattaattga tacaaaaatc 5450

 caacaacttt agcagtttgt ttaccagtta ttgagtacca actgtgttca 5500

 acattgttat ttcactcata tgaaatgata aatgtatgtg cttgttatga 5550

 tacggtcaat aaaaccactt ttataggaag aatacgccca aaaaatctat 5600

 gtcgggtgcg gagaaagagg taatgaaat 5629

<210> 4387
<211> 114
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 708-897
<223> Unknown amino acid

<400> 4387
 Met Val Leu Gly Pro Lys Ser Cys Ile Phe Thr His Ser Phe Ser
   1               5                  10                  15

 Leu Arg Ala Met Ala Ile Lys Gly Ser Asp Thr Phe Thr Tyr Leu
                  20                  25                  30

 Phe Leu Arg Gln Ala Val Asn Leu Ala Gly Phe Lys Leu Gln Ala
                  35                  40                  45

 Ala Ser Cys Ala Val Gly Ser Ser Leu Arg Ser Ile Gln Phe Phe
                  50                  55                  60

 Ser Phe His Ile Gly Trp Val Thr Leu Ser Leu Ala Tyr Met Met
                  65                  70                  75

 Gly Ser Leu Glu Val Asn Gln Arg Ile Ser Ala Glu Leu Ile His
                  80                  85                  90

 Arg Ile Ser Phe Arg Leu Pro Val Ser Asp Trp Leu Gln Cys Gly
                  95                 100                 105

 Asn Phe Leu Pro Leu Phe Ser His Tyr
                 110

<210> 4388
<211> 2473
<212> DNA
<213> Homo sapien

<400> 4388
 ttgtgatgaa cttcaaaaac aataattcta agtggaagac ctataaagga 50

 attgtgaata atgaagaaaa ggtgcttcag ggtaactcta actttcggga 100

 cccagtgcaa aacaatttca tccctcccat cgtggccaga tatgtgcggg 150

 ttgtccccca gacatggcac cagaggatag ccttgaaggt ggagctcatt 200

 ggttgccaga ttacacaagg taatgattca ttggtgtggc gcaagacaag 250

 tcaaagcacc agtgtttcaa ctaagaaaga agatgagaca atcacaaggc 300

 ccatcccctc ggaagaaaca tccacaggaa taaacattac aacggtggct 350

 attccattgg tgctccttgt tgtcctggtg tttgctggaa tggggatctt 400

 tgcagccttt agaaagaaga agaagaaagg aagtccgtat ggatcagcag 450

 aggctcagaa aacagactgt tggaagcaga ttaaatatcc ctttgccaga 500

 catcagtcag ctgagtttac catcagctat gataatgaga aggagatgac 550

 acaaaagtta gatctcatca caagtgatat ggcagattac cagcagcccc 600

 tcatgattgg caccgggaca gtcacgagga agggctccac cttccggccc 650

 atggacacgg atgccgagga ggcaggggtg agcaccgatg ccggcggcca 700

 ctatgactgc ccgcagcggg ccggccgcca cgagtacgcg ctgcccctgg 750

 cgcccccgga gcccgagtac gccacgccca tcgtggagcg gcacgtgctg 800

 cgcgcccaca cgttctctgc gcagagcggc taccgcgtcc cagggcccca 850

 gcccggccac aaacactccc tctcctcggg cggcttctcc cccgtagcgg 900

 gtgtgggcgc ccaggacgga gactatcaaa ggccacacag cgcacagcct 950

 gcggacaggg gctacgaccg gcccaaagct gtcagcgccc tcgccaccga 1000

 aagcggacac cctgactctc agaagccccc aacgcatccc gggacgagtg 1050

 acagctattc tgcccccaga gactgcctca cacccctcaa ccagacggcc 1100

 atgactgccc ttttgtgaac acaatgtgaa agaagcctgc tgtggtactg 1150

 agcgtcgggc tgtcacaagg cactggaaga agggagcctg ctggtccaga 1200

 gtgtgcgtgt gtatcggtgt gtgtgtacac ttgcatgtgt gtgtgtgatc 1250

 cagtaggatc ctagagacaa cctgtcatac tgtttacaaa attgtgcagc 1300

 tggtttcgtg ctgaccctta gggtgcgtct gttgggtttt gttgggctag 1350

 aaaaatgaaa atttttagat ggcgttttca ttcctctgac tgatattgag 1400

 ctgctttggt gttaaaggtg taatgtgtac agagttgtat ttaacaataa 1450

 taaaagtaac ttaagtttgc tctatcagat tttagttctg cacagaggtt 1500

 aagtgggaaa atgcagctgt tgcaaaatgt atataaatag tatgttcatt 1550

 tttttcagta tattatctga tactgtgtta gcagcaggtc tgcttaaacc 1600

 tagtcttgtt gttattgagt catttcctct cctttgataa ctagaactga 1650

 aagcattttt aacattcttc tcctggaaga aatgaattac ttgaagcatg 1700

 aaaagcacac cagggtggtt gtttatttag caattatgac tgtagattta 1750

 aaaacaagca aagaaacaac acctcagcag ctgcccgttt ccttagtctc 1800

 cacttcagag ggggatgcga agaggtcggc ccagctccgg tgaccatgaa 1850

 ggtggcacag gaattacagt gtgaatggct gtgtcagatg ttttcgtacc 1900

 tcagattaaa aatattgctg aggtcagacg ccacaatttt catgactttc 1950

 ttcagaagta gcacattttc gtgacttccg ctgtcctctg aaaaacaaag 2000

 ttatttggaa catgttcatg caaaagtgat tctgaccaag tctaaatcga 2050

 gcttttctac tgacatgaaa ctgttggaaa ctgatctcat tttataagaa 2100

 atgattttcc cctcaaggag gcgtctgtaa ttccagaaca gtccagacat 2150

 cagctgtacc tcatgctcag tagtttttat ttgagtttct tttgtgagtt 2200

 aactatggga gatttaacct cttttgccaa agagggaagt gtgtgtgttt 2250

 ttttaataga aaatatggac caaaaatttt tttccctgaa gaatgtatta 2300

 taaccctatt tgtgtggtta ttacatcctg tgaaatgtat atatgttaaa 2350

 ataatggggg tgctggaagg tcatggcaga ctagctgctg gttagtgtgg 2400

 aggggaagtg gtttactttg tagagtttac atggttttat gcgcacacta 2450

 attgtaataa actatgccaa acc 2473

<210> 4389
<211> 370
<212> PRT
<213> Homo sapien

<400> 4389
 Met Asn Phe Lys Asn Asn Asn Ser Lys Trp Lys Thr Tyr Lys Gly
   1               5                  10                  15

 Ile Val Asn Asn Glu Glu Lys Val Leu Gln Gly Asn Ser Asn Phe
                  20                  25                  30

 Arg Asp Pro Val Gln Asn Asn Phe Ile Pro Pro Ile Val Ala Arg
                  35                  40                  45

 Tyr Val Arg Val Val Pro Gln Thr Trp His Gln Arg Ile Ala Leu
                  50                  55                  60

 Lys Val Glu Leu Ile Gly Cys Gln Ile Thr Gln Gly Asn Asp Ser
                  65                  70                  75

 Leu Val Trp Arg Lys Thr Ser Gln Ser Thr Ser Val Ser Thr Lys
                  80                  85                  90

 Lys Glu Asp Glu Thr Ile Thr Arg Pro Ile Pro Ser Glu Glu Thr
                  95                 100                 105

 Ser Thr Gly Ile Asn Ile Thr Thr Val Ala Ile Pro Leu Val Leu
                 110                 115                 120

 Leu Val Val Leu Val Phe Ala Gly Met Gly Ile Phe Ala Ala Phe
                 125                 130                 135

 Arg Lys Lys Lys Lys Lys Gly Ser Pro Tyr Gly Ser Ala Glu Ala
                 140                 145                 150

 Gln Lys Thr Asp Cys Trp Lys Gln Ile Lys Tyr Pro Phe Ala Arg
                 155                 160                 165

 His Gln Ser Ala Glu Phe Thr Ile Ser Tyr Asp Asn Glu Lys Glu
                 170                 175                 180

 Met Thr Gln Lys Leu Asp Leu Ile Thr Ser Asp Met Ala Asp Tyr
                 185                 190                 195

 Gln Gln Pro Leu Met Ile Gly Thr Gly Thr Val Thr Arg Lys Gly
                 200                 205                 210

 Ser Thr Phe Arg Pro Met Asp Thr Asp Ala Glu Glu Ala Gly Val
                 215                 220                 225

 Ser Thr Asp Ala Gly Gly His Tyr Asp Cys Pro Gln Arg Ala Gly
                 230                 235                 240

 Arg His Glu Tyr Ala Leu Pro Leu Ala Pro Pro Glu Pro Glu Tyr
                 245                 250                 255

 Ala Thr Pro Ile Val Glu Arg His Val Leu Arg Ala His Thr Phe
                 260                 265                 270

 Ser Ala Gln Ser Gly Tyr Arg Val Pro Gly Pro Gln Pro Gly His
                 275                 280                 285

 Lys His Ser Leu Ser Ser Gly Gly Phe Ser Pro Val Ala Gly Val
                 290                 295                 300

 Gly Ala Gln Asp Gly Asp Tyr Gln Arg Pro His Ser Ala Gln Pro
                 305                 310                 315

 Ala Asp Arg Gly Tyr Asp Arg Pro Lys Ala Val Ser Ala Leu Ala
                 320                 325                 330

 Thr Glu Ser Gly His Pro Asp Ser Gln Lys Pro Pro Thr His Pro
                 335                 340                 345

 Gly Thr Ser Asp Ser Tyr Ser Ala Pro Arg Asp Cys Leu Thr Pro
                 350                 355                 360

 Leu Asn Gln Thr Ala Met Thr Ala Leu Leu
                 365                 370

<210> 4390
<211> 1097
<212> DNA
<213> Homo sapien

<400> 4390
 gcggcgatcg aggagctctg cggccgccaa gctgcgcggg cagaagcggt 50

 ccggggcctc cgcggccccc gcggcctccg cggccgctgc cttggcaccc 100

 agcgccaccc gcacacggcg ctccgctagc caggccggga gcaagagcca 150

 ggcggtggag aagccgccgt cggagaagcc gcggctgagg cgctcgtcgc 200

 cgcgggccca ggaggagggc ccgggggagc cgccgccgcc tgagctggcg 250

 ttgctcccgc caccgccgcc gccgccgccg actcccgcga ccccgacgtc 300

 ctcggcgtcc aacctggacc tgggcgagca gcgggagcgc tgggagacgt 350

 tccagaagcg gcagaagctt acctccgagg gtgccgccaa gctcctgcta 400

 gacacctttg aataccaggg cctggtgaag cacacaggag gctgccactg 450

 tggagcagtt cgttttgaag tttgggcctc agcagacttg catatatttg 500

 actgcaattg cagcatttgc aagaagaagc agaatagaca cttcattgtt 550

 ccagcttctc gcttcaagct cctgaaggga gctgagcaca taacgactta 600

 cacgttcaat actcacaaag cccagcatac cttctgtaag agatgtggcg 650

 ttcagagctt ctatactcca cgatcaaacc ccggaggctt cggaattgcc 700

 ccccactgcc tggatgaggg cactgtgcgg agtatggtca ctgaggaatt 750

 caatggcagc gattgggaga aggccatgaa agagcacaag accatcaaga 800

 acatgtctaa agagtgagct tctgcctctc ctgccctgaa aaggaggaat 850

 gattggggcc agcaactttg ctctccctgc cgtgcctcgg tggtgctcct 900

 gaatgtggct gacctgggct gctggttccg tggactaggg tcatcttgat 950

 ctctgcagtt tgctccagct accagtttct ttaggcagct ctttgtcctc 1000

 cctctgccca gattttgatg tagtctaatt gacatccttc tcttcccaac 1050

 ttttgtgtga tcttttagga aaaaaaataa atatttttaa cattaaa 1097

<210> 4391
<211> 271
<212> PRT
<213> Homo sapien

<400> 4391
 Arg Arg Ser Arg Ser Ser Ala Ala Ala Lys Leu Arg Gly Gln Lys
   1               5                  10                  15

 Arg Ser Gly Ala Ser Ala Ala Pro Ala Ala Ser Ala Ala Ala Ala
                  20                  25                  30

 Leu Ala Pro Ser Ala Thr Arg Thr Arg Arg Ser Ala Ser Gln Ala
                  35                  40                  45

 Gly Ser Lys Ser Gln Ala Val Glu Lys Pro Pro Ser Glu Lys Pro
                  50                  55                  60

 Arg Leu Arg Arg Ser Ser Pro Arg Ala Gln Glu Glu Gly Pro Gly
                  65                  70                  75

 Glu Pro Pro Pro Pro Glu Leu Ala Leu Leu Pro Pro Pro Pro Pro
                  80                  85                  90

 Pro Pro Pro Thr Pro Ala Thr Pro Thr Ser Ser Ala Ser Asn Leu
                  95                 100                 105

 Asp Leu Gly Glu Gln Arg Glu Arg Trp Glu Thr Phe Gln Lys Arg
                 110                 115                 120

 Gln Lys Leu Thr Ser Glu Gly Ala Ala Lys Leu Leu Leu Asp Thr
                 125                 130                 135

 Phe Glu Tyr Gln Gly Leu Val Lys His Thr Gly Gly Cys His Cys
                 140                 145                 150

 Gly Ala Val Arg Phe Glu Val Trp Ala Ser Ala Asp Leu His Ile
                 155                 160                 165

 Phe Asp Cys Asn Cys Ser Ile Cys Lys Lys Lys Gln Asn Arg His
                 170                 175                 180

 Phe Ile Val Pro Ala Ser Arg Phe Lys Leu Leu Lys Gly Ala Glu
                 185                 190                 195

 His Ile Thr Thr Tyr Thr Phe Asn Thr His Lys Ala Gln His Thr
                 200                 205                 210

 Phe Cys Lys Arg Cys Gly Val Gln Ser Phe Tyr Thr Pro Arg Ser
                 215                 220                 225

 Asn Pro Gly Gly Phe Gly Ile Ala Pro His Cys Leu Asp Glu Gly
                 230                 235                 240

 Thr Val Arg Ser Met Val Thr Glu Glu Phe Asn Gly Ser Asp Trp
                 245                 250                 255

 Glu Lys Ala Met Lys Glu His Lys Thr Ile Lys Asn Met Ser Lys
                 260                 265                 270

 Glu


<210> 4392
<211> 1097
<212> DNA
<213> Homo sapien

<400> 4392
 gcggcgatcg aggagctctg cggccgccaa gctgcgcggg cagaagcggt 50

 ccggggcctc cgcggccccc gcggcctccg cggccgctgc cttggcaccc 100

 agcgccaccc gcacacggcg ctccgctagc caggccggga gcaagagcca 150

 ggcggtggag aagccgccgt cggagaagcc gcggctgagg cgctcgtcgc 200

 cgcgggccca ggaggagggc ccgggggagc cgccgccgcc tgagctggcg 250

 ttgctcccgc caccgccgcc gccgccgccg actcccgcga ccccgacgtc 300

 ctcggcgtcc aacctggacc tgggcgagca gcgggagcgc tgggagacgt 350

 tccagaagcg gcagaagctt acctccgagg gtgccgccaa gctcctgcta 400

 gacacctttg aataccaggg cctggtgaag cacacaggag gctgccactg 450

 tggagcagtt cgttttgaag tttgggcctc agcagacttg catatatttg 500

 actgcaattg cagcatttgc aagaagaagc agaatagaca cttcattgtt 550

 ccagcttctc gcttcaagct cctgaaggga gctgagcaca taacgactta 600

 cacgttcaat actcacaaag cccagcatac cttctgtaag agatgtggcg 650

 ttcagagctt ctatactcca cgatcaaacc ccggaggctt cggaattgcc 700

 ccccactgcc tggatgaggg cactgtgcgg agtatggtca ctgaggaatt 750

 caatggcagc gattgggaga aggccatgaa agagcacaag accatcaaga 800

 acatgtctaa agagtgagct tctgcctctc ctgccctgaa aaggaggaat 850

 gattggggcc agcaactttg ctctccctgc cgtgcctcgg tggtgctcct 900

 gaatgtggct gacctgggct gctggttccg tggactaggg tcatcttgat 950

 ctctgcagtt tgctccagct accagtttct ttaggcagct ctttgtcctc 1000

 cctctgccca gattttgatg tagtctaatt gacatccttc tcttcccaac 1050

 ttttgtgtga tcttttagga aaaaaaataa atatttttaa cattaaa 1097

<210> 4393
<211> 2069
<212> DNA
<213> Homo sapien

<400> 4393
 aaaaaaagaa tgccaggggg gaattatcat gctaaattat tttactgctg 50

 aagatagctt cattgcaaat tattcttttt ccagaatttc ccccaaacaa 100

 cttagaattc cataagtaga acaagataga ttctaccccc aaaatattca 150

 taagcaaatc ccactgccct taaaataagg aagttatgcc tggttgtctg 200

 tgaatggaac ctcagtaggt aatcctgatg aagcttaaaa ccttagggca 250

 gtgtctacat gggaaacaag tatgtggaaa ttgacaatca tttttaccaa 300

 atcgttgagt aataatatga cttacctgat agatatacac attcaataag 350

 gaacattttt ttttttcaat aaggaacatt ttaactaaaa cattacttta 400

 gggctgagat ttccaggcta tctacattga tctactgaaa aatttctaga 450

 tttccatata caaacgaaga agacatgagt ttagagaatt tttttccttt 500

 aatttttttt taacagaagg gtatcagagt ggaggaccta gattacgcta 550

 cctgtgtttg aaaatattgc gctttgccta accttcggtg gaatgtattg 600

 tttcagcata ttctatgtat aaaaaagttt aaagatgtct tcaaagaaga 650

 ctagagtctt taagtcactt atagctatat tttactacaa aatttgtgta 700

 taaagatata tttaagtgtt ttagataaat ttaagttact ccatatgaaa 750

 tgtttaattt cagctactgt gaattctttc gatcagtcct ttgctttttt 800

 aaaaaatctt ttccatcgtg ttaaaaagaa aattagctat taggagatat 850

 taaaagattg atgtcttaga aggacagggt taaaaccttc tgtaatatat 900

 ttaaatatat atttttaaga gagatgctac attgccaatg attttataaa 950

 taatttaaaa ttaatttaca aatttataga tgcaaaccaa aagatctttt 1000

 taaaagagag agagaggaaa aaaatcacct tttatttgtt tgggtctcat 1050

 tgtcagaatt attattcaga tcaagaaatc tgtgtcgata aaacctaatc 1100

 tcatattgga gagtgaatgt cgttaagtat ttctgaaatg tttctaaaaa 1150

 atgaacatga aaaaaataag gtattttctc cctagcttct cattacagta 1200

 tttctaattg cttcacactt tacagtttta atacaaagta caagctctac 1250

 ttttataacg tgtactacaa gtttctttaa aagtattgtt gtatttcagc 1300

 tgaactcttg tatctgcagt cttttgttat ttctgcaggc tacaccctta 1350

 atttgcagag gccattttgt tgtttgtttg atgctgaagc tgttgttaaa 1400

 atgccccaaa ctccaaggca gattgtctgt ataatacgct atagcttttc 1450

 accatgtggt gtttaccagc tgttactctg tattttaaaa agccagagat 1500

 ttcttctgtc taaactgttt ctatagcatt ttctaaacaa aaaaaatggt 1550

 ttttttcttt gccttgtaat aagattgtaa atccatttcc tgcttgtgtt 1600

 cttagtgggc atgattgtga gtgtgtgtgg ggtgctcaca cgcgtgccag 1650

 tctttttgta ctgtaactac ctcatggttt gaatgatgat tgtactgctg 1700

 gttgtgttaa cagagcacat tttgttgggt gagtcctatg tgattttttt 1750

 catgtttgtt ttatctgggg gttgttcatg aaactgacag atgtttttct 1800

 aaaaaggact attatcagtt tccaaataca atacttctct cttctggttt 1850

 ttcctgaatg agcctgattt tgttgctggt tttcatcatc tatgagggta 1900

 aaacgagtac ccttaaaatc cctgtggcca gtttgaacac ccctgttgta 1950

 ttcttttctc tgttcagtgt gtcagctatt ttgtgaagat gcttagatgt 2000

 atagttttga taaccacagt tttaaatctt ttatctgtgc ataataaaaa 2050

 gatatatatc agttattaa 2069

<210> 4394
<211> 37
<212> PRT
<213> Homo sapien

<400> 4394
 Lys Lys Glu Cys Gln Gly Gly Ile Ile Met Leu Asn Tyr Phe Thr
   1               5                  10                  15

 Ala Glu Asp Ser Phe Ile Ala Asn Tyr Ser Phe Ser Arg Ile Ser
                  20                  25                  30

 Pro Lys Gln Leu Arg Ile Pro
                  35

<210> 4395
<211> 1527
<212> DNA
<213> Homo sapien

<400> 4395
 agttgcagaa agaagaaagg aaagggaaag aaaagtgttc agaaatcttt 50

 atatggggaa agagacattg cttctaagaa gcccctcctc agtcctattc 100

 ccgagctgcc tgaagtccct gagatgacac cttccattcc gagcatccga 150

 agactgggtt caggttattt cagttcaaat ggcaaactgg aagaagtgaa 200

 gactcctaaa aatccagtga aaagaaagga tcttttgcgt catgacccag 250

 atttgcatat gcatcaaggc tatgataaat atgatgtctc tgaattctgc 300

 tcttatataa aaagttcctc atcgcttggc aatgctactt ctgatgaaga 350

 tccaaataca aatataatga acattaatga aaataaaaat attccaaaag 400

 caaaaaataa gtcagaaagt gaaaatgaac caaaagctgg aactgacagt 450

 cctgtttctt gtgcttctat aactgaagaa cgtgtggcat cagatagtcc 500

 caaacctgct ctgaccctgc agcagggtca agaattttct gctggtggtc 550

 aaaatgcaga aaacctttgt cagttcttta aaatttcacc agatttaaac 600

 ataaagtgtg aaagaaagga tgacttctta ggagctgcag aaggaaaact 650

 gcaatgcaat cgtttaatgc ctaattcaca aaaagactgt cattgtttag 700

 gagatgtctt aattgaaaat acgaaagaat ctaaaagcca gagtgaggat 750

 ttgggaagaa aacccatgga aagtagcagt gttgtgagtt gcagagacag 800

 gaaagataga agacgttcca tgtgttattc tgatggtcga agtttacatt 850

 tggaaaaaaa tggaaatcac acaccatcct ccagtgtggg cagctctgta 900

 gaaattagtt tagaaaattc tgaactgttt aaagatttgt ctgatgccat 950

 tgagcaaacc tttcagagga gaaatagtga aaccaaagtg cgacgtagca 1000

 cgaggctaca gaaggattta gaaaacgaag gtcttgtatg gatttcactt 1050

 ccacttcctt ccacttccca aaaagccaaa agaagaacaa tatgtacatt 1100

 tgacagcagt ggatttgaaa gtatgtctcc cataaaagaa actgtgtcct 1150

 ccagacaaaa accgcagatg gcacctcccg tctcagatcc agaaaacagc 1200

 cagggccctg ctgctggttc ttccgatgaa cctggtaaga ggaggaagag 1250

 cttttgtata tctacacttg caaatactaa agccacttcc cagttcaaag 1300

 gctaccggag aagatcctct cttaatggga agggagagag ctctctgact 1350

 gccttggaaa ggattgaaca taatggagaa agaaagcagt aattgacatt 1400

 tcctgcagag tctgtagcaa gagggaaagt aaccatctat gctgaaatga 1450

 tctgtctagt tcccattctc tgttcaacct cagtgtttca aaagttccta 1500

 ataaataaac tcatttgagt tgaacct 1527

<210> 4396
<211> 422
<212> PRT
<213> Homo sapien

<400> 4396
 Met Thr Pro Ser Ile Pro Ser Ile Arg Arg Leu Gly Ser Gly Tyr
   1               5                  10                  15

 Phe Ser Ser Asn Gly Lys Leu Glu Glu Val Lys Thr Pro Lys Asn
                  20                  25                  30

 Pro Val Lys Arg Lys Asp Leu Leu Arg His Asp Pro Asp Leu His
                  35                  40                  45

 Met His Gln Gly Tyr Asp Lys Tyr Asp Val Ser Glu Phe Cys Ser
                  50                  55                  60

 Tyr Ile Lys Ser Ser Ser Ser Leu Gly Asn Ala Thr Ser Asp Glu
                  65                  70                  75

 Asp Pro Asn Thr Asn Ile Met Asn Ile Asn Glu Asn Lys Asn Ile
                  80                  85                  90

 Pro Lys Ala Lys Asn Lys Ser Glu Ser Glu Asn Glu Pro Lys Ala
                  95                 100                 105

 Gly Thr Asp Ser Pro Val Ser Cys Ala Ser Ile Thr Glu Glu Arg
                 110                 115                 120

 Val Ala Ser Asp Ser Pro Lys Pro Ala Leu Thr Leu Gln Gln Gly
                 125                 130                 135

 Gln Glu Phe Ser Ala Gly Gly Gln Asn Ala Glu Asn Leu Cys Gln
                 140                 145                 150

 Phe Phe Lys Ile Ser Pro Asp Leu Asn Ile Lys Cys Glu Arg Lys
                 155                 160                 165

 Asp Asp Phe Leu Gly Ala Ala Glu Gly Lys Leu Gln Cys Asn Arg
                 170                 175                 180

 Leu Met Pro Asn Ser Gln Lys Asp Cys His Cys Leu Gly Asp Val
                 185                 190                 195

 Leu Ile Glu Asn Thr Lys Glu Ser Lys Ser Gln Ser Glu Asp Leu
                 200                 205                 210

 Gly Arg Lys Pro Met Glu Ser Ser Ser Val Val Ser Cys Arg Asp
                 215                 220                 225

 Arg Lys Asp Arg Arg Arg Ser Met Cys Tyr Ser Asp Gly Arg Ser
                 230                 235                 240

 Leu His Leu Glu Lys Asn Gly Asn His Thr Pro Ser Ser Ser Val
                 245                 250                 255

 Gly Ser Ser Val Glu Ile Ser Leu Glu Asn Ser Glu Leu Phe Lys
                 260                 265                 270

 Asp Leu Ser Asp Ala Ile Glu Gln Thr Phe Gln Arg Arg Asn Ser
                 275                 280                 285

 Glu Thr Lys Val Arg Arg Ser Thr Arg Leu Gln Lys Asp Leu Glu
                 290                 295                 300

 Asn Glu Gly Leu Val Trp Ile Ser Leu Pro Leu Pro Ser Thr Ser
                 305                 310                 315

 Gln Lys Ala Lys Arg Arg Thr Ile Cys Thr Phe Asp Ser Ser Gly
                 320                 325                 330

 Phe Glu Ser Met Ser Pro Ile Lys Glu Thr Val Ser Ser Arg Gln
                 335                 340                 345

 Lys Pro Gln Met Ala Pro Pro Val Ser Asp Pro Glu Asn Ser Gln
                 350                 355                 360

 Gly Pro Ala Ala Gly Ser Ser Asp Glu Pro Gly Lys Arg Arg Lys
                 365                 370                 375

 Ser Phe Cys Ile Ser Thr Leu Ala Asn Thr Lys Ala Thr Ser Gln
                 380                 385                 390

 Phe Lys Gly Tyr Arg Arg Arg Ser Ser Leu Asn Gly Lys Gly Glu
                 395                 400                 405

 Ser Ser Leu Thr Ala Leu Glu Arg Ile Glu His Asn Gly Glu Arg
                 410                 415                 420

 Lys Gln


<210> 4397
<211> 2920
<212> DNA
<213> Homo sapien

<400> 4397
 cgccaggaga ccccaagctg catcgccgag tggaagcaac tagaactcca 50

 gggctgtgaa agccacaggt gggggctgag cgaggcgtgg cctcaggagc 100

 ggaggacccc cccccactct ccctcgagcg ccgcagtcca ccgtagcggg 150

 tggagcccgc cttggtgcgc agttggaaaa cctcggagcc ccgctggatc 200

 tcctggctgc cacccgcacc ccccgccagc ctacgcccca ccgtagagat 250

 gccttcttcg gtgacggcgc tgggtcaggc caggtcctct ggccccggga 300

 tggccccgag cgcctgctgc tgctcccctg cggccctgca gaggaggctg 350

 cccatcctgg cgtggctgcc cagctactcc ctgcagtggc tgaagatgga 400

 tttcgtcgcc ggcctctcag ttggcctcac tgccattccc caggcgctgg 450

 cctatgctga agtggctgga ctcccgcccc agtatggcct ctactctgcc 500

 ttcatgggct gcttcgtgta tttcttcctg ggcacctccc gggatgtgac 550

 tctgggcccc accgccatta tgtccctcct ggtctccttc tacaccttcc 600

 atgagcccgc ctacgctgtg ctgctggcct tcctgtccgg ctgcatccag 650

 ctggccatgg gggtcctgcg tttggggttc ctgctggact tcatttccta 700

 ccccgtcatt aaaggcttca cctctgctgc tgccgtcacc atcggctttg 750

 gacagatcaa gaacctgctg ggactacaga acatccccag gccgttcttc 800

 ctgcaggtgt accacacctt cctcaggatt gcagagacca gggtaggtga 850

 cgccgtcctg gggctggtct gcatgctgct gctgctggtg ctgaagctga 900

 tgcgggacca cgtgcctccc gtccaccccg agatgccccc tggtgtgcgg 950

 ctcagccgtg ggctggtctg ggctgccacg acagctcgca acgccctggt 1000

 ggtctccttc gcagccctgg ttgcgtactc cttcgaggtg actggatacc 1050

 agcctttcat cctaacaggg gagacagctg aggggctccc tccagtccgg 1100

 atcccgccct tctcagtgac cacagccaac gggacgatct ccttcaccga 1150

 gatggtgcag gacatgggag ccgggctggc cgtggtgccc ctgatgggcc 1200

 tcctggagag cattgcggtg gccaaagcct tcgcatctca gaataattac 1250

 cgcatcgatg ccaaccagga gctgctggcc atcggtctca ccaacatgtt 1300

 gggctccctc gtctcctcct acccggtcac aggcagcttt ggacggacag 1350

 ccgtgaacgc tcagtcgggg gtgtgcaccc cggcgggggg cctggtgacg 1400

 ggagtgctgg tgctgctgtc tctggactac ctgacctcac tgttctacta 1450

 catccccaag tctgccctgg ctgccgtcat catcatggcc gtggccccgc 1500

 tgttcgacac caagatcttc aggacgctct ggcgtgttaa gaggctggac 1550

 ctgctgcccc tgtgcgtgac cttcctgctg tgcttctggg aggtgcagta 1600

 cggcatcctg gccggggccc tggtgtctct gctcatgctc ctgcactctg 1650

 cagccaggcc tgagaccaag gtgtcagagg ggccggttct ggtcctgcag 1700

 ccggccagcg gcctgtcctt ccctgccatg gaggctctgc gggaggagat 1750

 cctaagccgg gccctggaag tgtccccgcc acgctgcctg gtcctggagt 1800

 gcacccatgt ctgcagcatc gactacactg tggtgctggg actcggcgag 1850

 ctcctccagg acttccagaa gcagggcgtc gccctggcct ttgtgggcct 1900

 gcaggtcccc gttctccgtg tcctgctgtc cgctgacctg aaggggttcc 1950

 agtacttctc taccctggaa gaagcagaga agcacctgag gcagaagcca 2000

 gggacccagc cctacaacat cagagaagac tccattctgg accaaaaggt 2050

 tgccctgctc aaggcataat ggggccaccc gtgggcatcc acagtttgca 2100

 gggtgttccg gaaggttctt gtcactgtga ttggatgctg gatgccgcct 2150

 gatagacatg ctggcctggc tgagaaaccc ctgagcaggt aacccaggga 2200

 agagaaggaa gccaggcctg gaggtccacg gcagtgggag tggggctcac 2250

 tggcttcctg tgggatgact ggaaaatgac ctcgctgctg ttccctggca 2300

 tgaccctctt tggaagagtg gtttggagag agccttctag aatgacagac 2350

 tgtgcgagga agcaggggca ggggtttcca gcccgggctg tgcgaggcat 2400

 cctggggctg gcagcacctt cccggctcac cagtgccacc tgcgggggag 2450

 ggacggggca ggcaggagtc tgggaggcgg gtccgctcct cttgtctgcg 2500

 gcatctgtgc tctccgagag aaaaccaagg tgtgtcaaat gacgtcaagt 2550

 ctctatttaa aaataatttt gtgttttcta aatggaaaaa gtgatagctt 2600

 tggtgatttt gtaaaagtca taaatgctta ttgtaaaaaa tacaggaaac 2650

 cacccctcac cctgtccact tgggtgatca ttccagaccc ctccccaaac 2700

 atgcatatgt acctgtccgt cagtgtgtgg atgtatgttt acagttctac 2750

 ataaatggga tcattttata catggtgctc tggaacccac atttttcatg 2800

 cagtcatttg cagtgaatta tttattgtga taataaatag cattagaata 2850

 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2900

 aaaaaaaaaa aaaaaaaaaa 2920

<210> 4398
<211> 589
<212> PRT
<213> Homo sapien

<400> 4398
 Met Ala Pro Ser Ala Cys Cys Cys Ser Pro Ala Ala Leu Gln Arg
   1               5                  10                  15

 Arg Leu Pro Ile Leu Ala Trp Leu Pro Ser Tyr Ser Leu Gln Trp
                  20                  25                  30

 Leu Lys Met Asp Phe Val Ala Gly Leu Ser Val Gly Leu Thr Ala
                  35                  40                  45

 Ile Pro Gln Ala Leu Ala Tyr Ala Glu Val Ala Gly Leu Pro Pro
                  50                  55                  60

 Gln Tyr Gly Leu Tyr Ser Ala Phe Met Gly Cys Phe Val Tyr Phe
                  65                  70                  75

 Phe Leu Gly Thr Ser Arg Asp Val Thr Leu Gly Pro Thr Ala Ile
                  80                  85                  90

 Met Ser Leu Leu Val Ser Phe Tyr Thr Phe His Glu Pro Ala Tyr
                  95                 100                 105

 Ala Val Leu Leu Ala Phe Leu Ser Gly Cys Ile Gln Leu Ala Met
                 110                 115                 120

 Gly Val Leu Arg Leu Gly Phe Leu Leu Asp Phe Ile Ser Tyr Pro
                 125                 130                 135

 Val Ile Lys Gly Phe Thr Ser Ala Ala Ala Val Thr Ile Gly Phe
                 140                 145                 150

 Gly Gln Ile Lys Asn Leu Leu Gly Leu Gln Asn Ile Pro Arg Pro
                 155                 160                 165

 Phe Phe Leu Gln Val Tyr His Thr Phe Leu Arg Ile Ala Glu Thr
                 170                 175                 180

 Arg Val Gly Asp Ala Val Leu Gly Leu Val Cys Met Leu Leu Leu
                 185                 190                 195

 Leu Val Leu Lys Leu Met Arg Asp His Val Pro Pro Val His Pro
                 200                 205                 210

 Glu Met Pro Pro Gly Val Arg Leu Ser Arg Gly Leu Val Trp Ala
                 215                 220                 225

 Ala Thr Thr Ala Arg Asn Ala Leu Val Val Ser Phe Ala Ala Leu
                 230                 235                 240

 Val Ala Tyr Ser Phe Glu Val Thr Gly Tyr Gln Pro Phe Ile Leu
                 245                 250                 255

 Thr Gly Glu Thr Ala Glu Gly Leu Pro Pro Val Arg Ile Pro Pro
                 260                 265                 270

 Phe Ser Val Thr Thr Ala Asn Gly Thr Ile Ser Phe Thr Glu Met
                 275                 280                 285

 Val Gln Asp Met Gly Ala Gly Leu Ala Val Val Pro Leu Met Gly
                 290                 295                 300

 Leu Leu Glu Ser Ile Ala Val Ala Lys Ala Phe Ala Ser Gln Asn
                 305                 310                 315

 Asn Tyr Arg Ile Asp Ala Asn Gln Glu Leu Leu Ala Ile Gly Leu
                 320                 325                 330

 Thr Asn Met Leu Gly Ser Leu Val Ser Ser Tyr Pro Val Thr Gly
                 335                 340                 345

 Ser Phe Gly Arg Thr Ala Val Asn Ala Gln Ser Gly Val Cys Thr
                 350                 355                 360

 Pro Ala Gly Gly Leu Val Thr Gly Val Leu Val Leu Leu Ser Leu
                 365                 370                 375

 Asp Tyr Leu Thr Ser Leu Phe Tyr Tyr Ile Pro Lys Ser Ala Leu
                 380                 385                 390

 Ala Ala Val Ile Ile Met Ala Val Ala Pro Leu Phe Asp Thr Lys
                 395                 400                 405

 Ile Phe Arg Thr Leu Trp Arg Val Lys Arg Leu Asp Leu Leu Pro
                 410                 415                 420

 Leu Cys Val Thr Phe Leu Leu Cys Phe Trp Glu Val Gln Tyr Gly
                 425                 430                 435

 Ile Leu Ala Gly Ala Leu Val Ser Leu Leu Met Leu Leu His Ser
                 440                 445                 450

 Ala Ala Arg Pro Glu Thr Lys Val Ser Glu Gly Pro Val Leu Val
                 455                 460                 465

 Leu Gln Pro Ala Ser Gly Leu Ser Phe Pro Ala Met Glu Ala Leu
                 470                 475                 480

 Arg Glu Glu Ile Leu Ser Arg Ala Leu Glu Val Ser Pro Pro Arg
                 485                 490                 495

 Cys Leu Val Leu Glu Cys Thr His Val Cys Ser Ile Asp Tyr Thr
                 500                 505                 510

 Val Val Leu Gly Leu Gly Glu Leu Leu Gln Asp Phe Gln Lys Gln
                 515                 520                 525

 Gly Val Ala Leu Ala Phe Val Gly Leu Gln Val Pro Val Leu Arg
                 530                 535                 540

 Val Leu Leu Ser Ala Asp Leu Lys Gly Phe Gln Tyr Phe Ser Thr
                 545                 550                 555

 Leu Glu Glu Ala Glu Lys His Leu Arg Gln Lys Pro Gly Thr Gln
                 560                 565                 570

 Pro Tyr Asn Ile Arg Glu Asp Ser Ile Leu Asp Gln Lys Val Ala
                 575                 580                 585

 Leu Leu Lys Ala


<210> 4399
<211> 4657
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2726-2752
<223> Unknown base

<400> 4399
 ggtggccagt actactggga caaattgtgt tttttattat taataataat 50

 gataataata ctatccctcc aaggcacaag tgaactatat agaactgcgt 100

 gtgtgtaaac tctttactct cgtctcattt tgttgagttt agaacttgat 150

 gtgctcgtca gtcttgtgtt tcaaaacact gaataacttc caaagcaaag 200

 ttatgccagt gtgttcaaaa gataaattaa taatgtacca gcaaagagca 250

 tcattcaaag tatagtcctt gcatattcca gttaccattt ctctaataat 300

 taaaatattc atgataaata tatatatagc atcatatgtt aaaaactatt 350

 tcaaattcta catattaagg atgaaaattt taaaatccag taataagagg 400

 agagacctgc ctatcagtac agtgatatag gtaaaagatg aaatatgttt 450

 ttaaaatacc agcaattaac tattgttttc atgtgttctc ctctagaagc 500

 aaaccaaaaa ttccttcatg gaaaacaatt cttacttcta catgtgtagt 550

 ttatatctga tgcattacaa gagctaatgt ttaaagacaa aacaaaacct 600

 gcctgtatga cagcagcaac tcgagccaac atttagtgtt acatgttata 650

 tttttgaaat accgttttgt tatcatattc cacatattac tttccataaa 700

 gtcagagaag ttcaatgtaa attgttggct ctgattcttc caccttggga 750

 tacacattca caagaagatt tatatatttt cttactatga tagaggaaca 800

 taatctggga aaacttccca tgtctgtaag atgaaaagga tacctttacc 850

 atgttgtttt tgataataaa gaatatggaa aatggtagaa atctctcctc 900

 tctatgtgta tttgtatatg tgtgtataca cacacacgtt attgacattt 950

 ttacataaca tgtgattgcc acttcttata aagttatgat atagaacccc 1000

 atgaaaacaa ctttatatta tagatcaaat aatgtgccca gaaacgcaat 1050

 tgcaacagta aatcttgatc tattggtaag agtctatgat acaggtcttc 1100

 attctatccc taaacataat gttagtaaag aggttccatc agattgtatt 1150

 atagagacct tcctattgct atttattttt aagagatgag aagactgact 1200

 agcaatgtct ccacagtgca atggtttcac ttctgggtct gtctgtctgt 1250

 tgtgtaggtg agatcagtgt tgtcaggctc tcagaataat ttttaaaaga 1300

 atccagaagc ctgacttcac accaagtagc catcctagat gggcgggggg 1350

 gatctccatg ttcaaccaaa ccctcagaac ttagagcaat aaatacattc 1400

 agtcatttat ttataaatga atgacagaat attcaatcca aatagaaaca 1450

 accttttgtc agtgatgcaa cataacatgg agtcttatat tgagaaagtg 1500

 aatatgaata ttttaaatag atgcctagga aatctgtgtt tgctgtttac 1550

 atttaatgta ctttgccaca ttagcagtac cacacttctt ttactttcat 1600

 ccttctaaga actaatgaaa gatagcttgc tattagcttt gacatgttgc 1650

 acatgccatt atgttgttct ctaagaacaa ctaaattctc tccagtgttc 1700

 atgtgtgatt cctttttcat cattattact ttaatgtgga tgaatactat 1750

 ttctaggaac ttgattatca ctgaacagat tgcatatgta aatgcagata 1800

 attcttgagc aatatagtga aaatgatttc acacacagtt tgaaatctca 1850

 tattaaacag tggtaaattt ttaaacatta ggacattagc tggctgcttc 1900

 tataaatgta cctgtattgt ctgcctgctc cttttgtgga gatgtgtttt 1950

 tgtattggat gtttgggcca atgggaggct tcaagctaca acatattttc 2000

 ccactttaaa taatatttaa catatgacaa accccagaca aggcttttaa 2050

 tatgtataaa gaactgcagt gttaggtggt ttatttgcaa actgttttca 2100

 gtgttgtcca tttttatggc acctttaaca atattcttgt ttccaaagta 2150

 caaaaaaaat aggttaaata atctagccat aactgaatgt caagcaataa 2200

 aacaaatgac ttttgtgcat agacttaaaa aatacaaatt ttagacatct 2250

 gcatgtaaat gcaatctctt gtttactgct ttcttcaact tgagcaatcg 2300

 attccttatt tactattaac ttaagaactt gtaacggcct gtaaacattt 2350

 tctctcttac tcttctttca aatttacctg tccctgcttt tgagtcataa 2400

 tatttaatgt tgttctgcac atctctatac agttaacttt ttggctttca 2450

 ttctgtatag ataagaaaat gttatattat aaacagccta ctcagtgcaa 2500

 atatttatct gtttatcaaa tccacaatat gctgtataat accggtttta 2550

 ctatataatc tattttagac atagctgttt agaactagag tgtgctattt 2600

 ttgtgttttt ctgatgtgtg gtgctagaca agttactttt gtgaacaaca 2650

 aaaattatcc cttttattcc tagacaatac cacctttggg tcttgttaat 2700

 ttcactgagt ataactatat atttgnnnnn nnnnnnnnnn nnnnnnnnnn 2750

 nnccctatgc ccaactggca gctgtatcag agtgctggat ttgggacatg 2800

 cttttctctt taaatacata atatcattat ataaattatt ctagagtgta 2850

 tttaattagg ataaaattac ttccttagta tggatatttg acatctatag 2900

 ggtgaatttg tttataaata tggctatatg gaaacttatt agcatttact 2950

 ttatgtttgc tacttggctt tacagcatat ctcctaagct gaaaaataat 3000

 ttgccaggcc ttcaagatcc taaagaaact tgtttaatgg agtaatatac 3050

 ttttttttct tattaaggaa ttgtattact ggcacctaac acagttgtat 3100

 tcttagctcc tattatagat aatgggcatt tacataaaat atcctagatg 3150

 gcttgatggc agaataaacc tttcccctcc tacctgagtc atgagaagga 3200

 tggagacgtc ctctgccata acatgggcca taaagcaaat tcgacatggg 3250

 atgttctgtt tcagtatgac ctcaaccagt tccatgaact gagtgaagga 3300

 ccttcatttt caaagttatt taataagtag cttaattaag cctttctacc 3350

 cattctccca agatctattg gcattattga aaagcaaagt ttatcaaata 3400

 tctaactaag gatgtagtta accttattaa atattgatta gaattgttct 3450

 gtaatattac tgaatttgta agatctttag caaagatttt tgagcaattt 3500

 ataaatgtag agcaaatgtt tctgtttact gcactttttg taactgaagg 3550

 tgataaattc tcaagccatg attattggct tccatgcact gcagtattta 3600

 tccacaattc tagacatttt ccatttttgt ggaagagttg ctgttacctt 3650

 aattataaat gcaattgtgt ggttaatgag agctaatact agtagttaac 3700

 cttttaaagt ggattggcta cagttgaggg agaaatctct tttaatataa 3750

 atcacatcat tccttaactg cctctcttgg aaagagattg aaaccttttt 3800

 tttaaagcac gatttagcat cctaagcttc ctgagggtag agattgtatc 3850

 tttttgcgtc tgcacaatgg ctagcacatg tcagcatttg acaattgtta 3900

 aatgataaca agtgtgcccc aattaaaacg tttttcctgg gttgttttgt 3950

 taaatttaca aagtaagcca agccttacgg ttaacattct cctctacaac 4000

 caagtattaa agccacattt aaaaagacca catgaaatgc tgattctaat 4050

 tgtgtgtagg tcttgaggat taagcacaca aatttcacaa acttctgttt 4100

 gagtaaacaa actcagcctt ctgtaaatat acatgcaagt ttggaaacag 4150

 taatactgta cctataaata tatgctgtct gttttgtgta cagtatgtaa 4200

 aaactccttt tctgccacac taaaaatgca agccatttat gggaatccta 4250

 aaactagtat tgaactaaaa ctttgctaat gatctttatt agaggatcgt 4300

 ccaacttttc acttaccttg ggttttcttt tcaattcact cttacactag 4350

 tctgcttatt tccagctgtt tattttattg agtcctgaat ttaaaaaaaa 4400

 aatattttga ttcattttgt aaatacaagc tgtacaaaaa agagagattt 4450

 aatgttgtct tttaaatact ccaattttca ttctaatatg aatgttgtta 4500

 tattgtactt agaaactgta cctttaatat tacattacct ttattaaaag 4550

 tgcattgaac acatcaattt tagatgtgct ttatgtactg ttatcctata 4600

 ataaaacttc agcttctaat ggaaaaaaca aaaaaaaggg gcgcgccgcc 4650

 gattatt 4657

<210> 4400
<211> 27
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2726-2752
<223> Unknown amino acid

<400> 4400
 Met Cys Phe Met Tyr Cys Tyr Pro Ile Ile Lys Leu Gln Leu Leu
   1               5                  10                  15

 Met Glu Lys Thr Lys Lys Arg Gly Ala Pro Pro Ile
                  20                  25

<210> 4401
<211> 3926
<212> DNA
<213> Homo sapien

<400> 4401
 cccggcgcgg gcttcccgta cggcgggggc gccctgcagc cgtcgcctca 50

 gcagctctac ggcggctacc aggccagcca aggcagcgat gatgactggg 100

 acgacgagtg ggacgacagc tccacggtgg cggacgagcc gggcgctctg 150

 ggcagcggag catacccgga cctcgacggc tcgtcttcgg cgggtgtggg 200

 cgcagccggc cgctaccgcc tgtccacgcg ctccgacctg tccctgggct 250

 cccgcggcgg ctcggtcccc ccgcagcacc acccgtcggg gcccaagagc 300

 tcggccaccg tgagccgcaa cctcaatcgc ttctccacct tcgtcaagtc 350

 cggcggggag gccttcgtgc tgggggaggc gtcaggcttc gtgaaggacg 400

 gggacaagct gtgcgtggtg ctggggccct atggccccga gtggcaggag 450

 aacccctacc cgttccagtg caccatcgac gaccccacca agcagaccaa 500

 gttcaagggc atgaagagct acatctccta caagctggtg cccacgcaca 550

 cgcaggtgcc ggtgcatcgg cgctacaagc acttcgactg gctgtacgcg 600

 cgcctggcgg agaagttccc ggtcatctcc gtgccccacc tgcccgagaa 650

 gcaggccacc ggccgcttcg aggaggactt catctctaag cgcaggaagg 700

 gcctgatctg gtggatgaac cacatggcca gccacccagt gctggcgcag 750

 tgcgacgtct tccagcactt cctgacgtgc cccagcagca ccgacgagaa 800

 agcctggaag cagggcaaga ggaaggccga gaaggacgag atggtgggcg 850

 ccaacttctt cctgaccctt agcacgcccc ccgccgctgc ccttgacctg 900

 caggaggtgg agagcaagat cgacggcttc aagtgcttca ccaagaagat 950

 ggacgacagc gcgctgcagc tcaaccacac ggccaacgag ttcgcgcgca 1000

 agcaggtgac cggcttcaaa aaggagtatc agaaggtggg ccagtccttc 1050

 cgcggcctca gccaggcctt tgagctggac cagcaggcct tctcggtggg 1100

 cctgaaccag gctatcgcct tcacaggaga tgcctatgac gccattggcg 1150

 agctcttcgc ggagcagccc aggcaggacc tggatcccgt catggaccta 1200

 ttagcgctgt atcaggggca tctggctaac ttcccggaca tcatccacgt 1250

 tcagaaagga gctcttacca aagtcaagga gagtaggcga cacgtggagg 1300

 aagggaagat ggaggtgcag aaggctgacg gcattcagga tcgctgtaac 1350

 actatttctt ttgccacttt ggctgaaatt caccacttcc atcaaattcg 1400

 agtgagagac tttaaatcac agatgcagca tttcttacaa caacaaataa 1450

 tatttttcca aaaagttacc cagaagttgg aagaagctct tcacaaatat 1500

 gatagtgttt aatgactgga cgttggatta tgaagtctgt tagggaagaa 1550

 acagtgccac tattccctta gatgcaacag tagcatagcc tcttcaccca 1600

 ggcgtcccaa aagcttggcg tgaagatttc agcaaacatg tcttacaaca 1650

 tgaggaggag gagtctaaat cagtcagggg ataaaagtat cgaatcattg 1700

 acaacacaca cttggcttta gttcttagga gggttttgtt tttgtttttg 1750

 tttttaggtt gaagattttc ttttaatatt cagttttttg aaaaaaaatg 1800

 gatctacact gttaactgat tgagactcca ctgtgattca cttgtttact 1850

 taaaaacttt tcagggatgt ctgtaaattt cagtgttaat atgtcatgaa 1900

 aagtggtgtg gattgatcta aggagggacc agaaataatt tttgctattc 1950

 caaatactga aggaaaaaga taattgattt atactatgtt ttaaaaaaaa 2000

 aaaggtattg atgagccccc ccccccagga catttaacct taaaatttat 2050

 tttaaatgta ttcttttatt attataaggg aaatacagat ggctgataaa 2100

 taccaaaaag attcaaaagc agcttaattt aaaaagcaca aagagattct 2150

 ggcttacagt gccccaatct caatgttttt atagttgctg agctaactaa 2200

 tgtgattatt gagtttacag atttaaaaat tgtcactgtt agagtatcta 2250

 ctgtttttat gaagtcaaac ttatgctgcc tcagaaatcc ctgggtactg 2300

 aaatggtaac atggaagtga agaggtcact ttgaaatatt ggtgagtcac 2350

 aaagattaaa gaaaaggatc agtttgcaga tactcagaaa aggttattga 2400

 aataattact gaacagcaca ttttctctct aaaaagtagt ttcatatggg 2450

 ttgtattttt aagatcagat tatcattttg atatttggtc aaaattttgt 2500

 accttaggtt acttagagcc agatttaaca tcatgaacat tatgtggctt 2550

 tgtctttact acagatatgt ggaactgtaa ccaaatatgt tgtctctaaa 2600

 acttgttgat tgcaaaatac agttctataa acaaaaccca tatgtatata 2650

 taaatgttaa ttttgcggaa gtctggaaat tataactata gcatttaagt 2700

 ttgagtctgt attggacaaa taagcaccat gcttttcaaa tgatttaaaa 2750

 attactttta tttgcctctt tattttgatg gtggttggat tttttttttt 2800

 aatagtaaaa tcactaaact tgtgcaatgg tagcatggaa attatctgag 2850

 gtatattgta tgattgtact ttagccaggg tggacatagc ttaaattata 2900

 aaaactaaag atgaaagtac aaggaagtat aagttatact tatgtaagta 2950

 taaattcatg ctgcctactt ctaagagaaa tttcattctt cataaccaca 3000

 taacattata atgccactga ttcatacggg atttacatta attctatggg 3050

 ggaggacact agaattatta gtgttcattt tcatctaaga tctttattct 3100

 ctaacgttct tggtcctatt gaaacattgc agtatgcaaa actactgcaa 3150

 tgttaaaccc aagagaaaag ccattatcat gtgtatgctg gtcatcatga 3200

 tcagtgtggt acaattttta aaaataaact atcatgccct tcatgccatt 3250

 atttgtcttt atttctatga tttataatcc tgatatgtga tgtgtttgta 3300

 acacagggtg tgcacttgag cctggtttta ctgtttttat tagacagagt 3350

 tgtttatatg ctgtaactgt aacgcagcga gactggttct acagccatgt 3400

 gtcgtaatct tgttccccgt ccaagctgtt gtatctgaag gtacccagtt 3450

 tgcacccagg atgagggaac gcattcaaaa gtgaaatgta aagccagtgc 3500

 acgaatatta tagtaattga gattttccca ggcttcactg atacagttgt 3550

 tttgcattta ttcacaataa tacagcagat tcttaaatgc cgatttttaa 3600

 ttgtcttaaa ttttgctgct gttctcataa ttaaggactt gaaaaatgtt 3650

 ttagtctgtc aagtatgtaa agtttgtgta aaaactttta aatgtcattc 3700

 ttaagttcat tgccatagcc attttccatt tatgtcttca ttttccaaaa 3750

 atcaaatgcc atgtctgata cctttaagtc cataagcatt caattttctc 3800

 atttccacct tcatctttgg ttaacagaat aagtaaaaca gggtattatt 3850

 tatttgtagt ctagaaatgt tgaatattgt tttatttcct tcaaaatgtt 3900

 atgattagtg cagatcagcc atgttt 3926

<210> 4402
<211> 503
<212> PRT
<213> Homo sapien

<400> 4402
 Pro Gly Ala Gly Phe Pro Tyr Gly Gly Gly Ala Leu Gln Pro Ser
   1               5                  10                  15

 Pro Gln Gln Leu Tyr Gly Gly Tyr Gln Ala Ser Gln Gly Ser Asp
                  20                  25                  30

 Asp Asp Trp Asp Asp Glu Trp Asp Asp Ser Ser Thr Val Ala Asp
                  35                  40                  45

 Glu Pro Gly Ala Leu Gly Ser Gly Ala Tyr Pro Asp Leu Asp Gly
                  50                  55                  60

 Ser Ser Ser Ala Gly Val Gly Ala Ala Gly Arg Tyr Arg Leu Ser
                  65                  70                  75

 Thr Arg Ser Asp Leu Ser Leu Gly Ser Arg Gly Gly Ser Val Pro
                  80                  85                  90

 Pro Gln His His Pro Ser Gly Pro Lys Ser Ser Ala Thr Val Ser
                  95                 100                 105

 Arg Asn Leu Asn Arg Phe Ser Thr Phe Val Lys Ser Gly Gly Glu
                 110                 115                 120

 Ala Phe Val Leu Gly Glu Ala Ser Gly Phe Val Lys Asp Gly Asp
                 125                 130                 135

 Lys Leu Cys Val Val Leu Gly Pro Tyr Gly Pro Glu Trp Gln Glu
                 140                 145                 150

 Asn Pro Tyr Pro Phe Gln Cys Thr Ile Asp Asp Pro Thr Lys Gln
                 155                 160                 165

 Thr Lys Phe Lys Gly Met Lys Ser Tyr Ile Ser Tyr Lys Leu Val
                 170                 175                 180

 Pro Thr His Thr Gln Val Pro Val His Arg Arg Tyr Lys His Phe
                 185                 190                 195

 Asp Trp Leu Tyr Ala Arg Leu Ala Glu Lys Phe Pro Val Ile Ser
                 200                 205                 210

 Val Pro His Leu Pro Glu Lys Gln Ala Thr Gly Arg Phe Glu Glu
                 215                 220                 225

 Asp Phe Ile Ser Lys Arg Arg Lys Gly Leu Ile Trp Trp Met Asn
                 230                 235                 240

 His Met Ala Ser His Pro Val Leu Ala Gln Cys Asp Val Phe Gln
                 245                 250                 255

 His Phe Leu Thr Cys Pro Ser Ser Thr Asp Glu Lys Ala Trp Lys
                 260                 265                 270

 Gln Gly Lys Arg Lys Ala Glu Lys Asp Glu Met Val Gly Ala Asn
                 275                 280                 285

 Phe Phe Leu Thr Leu Ser Thr Pro Pro Ala Ala Ala Leu Asp Leu
                 290                 295                 300

 Gln Glu Val Glu Ser Lys Ile Asp Gly Phe Lys Cys Phe Thr Lys
                 305                 310                 315

 Lys Met Asp Asp Ser Ala Leu Gln Leu Asn His Thr Ala Asn Glu
                 320                 325                 330

 Phe Ala Arg Lys Gln Val Thr Gly Phe Lys Lys Glu Tyr Gln Lys
                 335                 340                 345

 Val Gly Gln Ser Phe Arg Gly Leu Ser Gln Ala Phe Glu Leu Asp
                 350                 355                 360

 Gln Gln Ala Phe Ser Val Gly Leu Asn Gln Ala Ile Ala Phe Thr
                 365                 370                 375

 Gly Asp Ala Tyr Asp Ala Ile Gly Glu Leu Phe Ala Glu Gln Pro
                 380                 385                 390

 Arg Gln Asp Leu Asp Pro Val Met Asp Leu Leu Ala Leu Tyr Gln
                 395                 400                 405

 Gly His Leu Ala Asn Phe Pro Asp Ile Ile His Val Gln Lys Gly
                 410                 415                 420

 Ala Leu Thr Lys Val Lys Glu Ser Arg Arg His Val Glu Glu Gly
                 425                 430                 435

 Lys Met Glu Val Gln Lys Ala Asp Gly Ile Gln Asp Arg Cys Asn
                 440                 445                 450

 Thr Ile Ser Phe Ala Thr Leu Ala Glu Ile His His Phe His Gln
                 455                 460                 465

 Ile Arg Val Arg Asp Phe Lys Ser Gln Met Gln His Phe Leu Gln
                 470                 475                 480

 Gln Gln Ile Ile Phe Phe Gln Lys Val Thr Gln Lys Leu Glu Glu
                 485                 490                 495

 Ala Leu His Lys Tyr Asp Ser Val
                 500

<210> 4403
<211> 7522
<212> DNA
<213> Homo sapien

<400> 4403
 cccgggcgag cccgccgtgc gcacagctct gcccgccgcc cctggagcgg 50

 atccccagcc gtccctgggc gttctcccgg gttctagcaa agccccccgg 100

 ggtgcccatc agtttccttg ggtgactaca gcgtgtgttt tttctttcct 150

 ctttcccctg cctgtgtgcc cttctccagg atggcagagg cggaattgca 200

 caaggaaagg ctgcaagcca tagcagaaaa aagaaagagg cagactgaaa 250

 tagaaggcaa gcgacaacag cttgacgagc agatacttct gctgcagcat 300

 tccaagtcca aagtgcttcg ggagaaatgg ctgctgcagg gcatacccgc 350

 tggaactgcc gaagaggagg aagccaggag gcggcagtct gaagaggatg 400

 agttcagagt caagcaactt gaagataaca ttcagaggct ggagcaagaa 450

 atacaaacgc tagaaagtga agagtcccag atatctgcca aagagcaaat 500

 catcctagag aaactgaagg aaacagaaaa atccttcaag gactttcaga 550

 agggtttctc cagtacggat ggagatgcag taaattacat ttcctcccag 600

 cttcccgacc tgccaatcct ctgttcacga acagcagaac catcacctgg 650

 gcaggacggg accagcagag cggctggagt cgggtgggag aatgtgctgc 700

 taaaggaagg tgagtcagcc tcgaacgcca cagaaacatc cggcccagac 750

 atgactatca agaagcctcc ccagctttct gaggatgata tctggctaaa 800

 aagcgaggga gacaactata gtgccaccct cctggagcct gctgccagct 850

 ctctttcccc agatcacaaa aacatggaaa ttgaggtgtc tgttgcagaa 900

 tgtaaaagtg ttcctggaat cacctctacc ccacatccca tggaccatcc 950

 ctccgctttc tattcacccc cgcataatgg cctccttact gatcaccacg 1000

 aatccctgga taatgatgtt gccagagaga tccgctatct agatgaggtg 1050

 ctagaggcca actgctgtga ttctgctgtg gatggaacgt acaatggaac 1100

 atcctcccca gagcctggtg cagtggttct ggtgggcggc ctaagccccc 1150

 ctgtccacga ggcgacccag ccagaaccca ctgaaagaac agctagccgg 1200

 caggcacctc ctcacatcga gctcagtaat agcagccctg accccatggc 1250

 agaggcagaa agaacaaatg gccattcccc cagccagcct agagatgcgc 1300

 tgggggacag cctgcaggtg cctgtcagcc ccagctccac aaccagctca 1350

 cggtgttctt cccgagatgg agagttcact ctcaccacac tgaaaaagga 1400

 ggccaagttt gagctgcgtg ccttccatga ggacaagaag ccctccaagc 1450

 tctttgagga tgacgagcat gagaaagaac aatactgcat tagaaaagtg 1500

 aggccttcag aggagatgct ggagctggaa aaggagagga gagagctcat 1550

 ccgcagccag gccgtcaaga agaatcctgg cattgcagca aaatggtgga 1600

 atcccccgca ggaaaaaacc atcgaggagc agctggacga ggaacatctg 1650

 gagtcgcaca aaaagtacaa ggagcgcaaa gagagaaggg cacagcagga 1700

 acagttgctg ctgcagaagc agttacagca gcagcagcag cagcccccat 1750

 cgcagctctg cacagcccct gcctcttctc atgaacgcgc aagcatgatt 1800

 gacaaagcaa aggaggacat tgtcacagag cagatagatt tctctgctgc 1850

 tcgcaaacaa tttcagctga tggagaattc caggcaagcg gtggccaagg 1900

 gccagagtac acccaggctg ttctccatca agcctttcta caggcctctg 1950

 gggtcagtca actcagacaa gccactgact aatccgagac caccttctgt 2000

 cgggggacct ccagaagaca gtggtgcctc agccgccaag ggacagaaat 2050

 cccccggtgc cctggagacc ccatcggcag caggaagcca gggcaacaca 2100

 gcctctcagg ggaaggaagg gccctacagc gagccttcta aacgtgggcc 2150

 cttatctaaa ctgtgggctg aggatggaga atttacgagc gcccgggctg 2200

 tcctcactgt ggtcaaggat gatgaccatg ggattttgga tcagttctca 2250

 agatctgtca atgtctcctt gacccaagag gagcttgact ctggtctgga 2300

 cgaattgtcg gtgaggtctc aggataccac agtcctggag accctatcca 2350

 atgatttcag catggacaac atcagtgaca gcggggcatc caatgagaca 2400

 accaatgccc tccaggaaaa ttcactggct gatttttctc tgccccagac 2450

 accacaaact gacaacccct cagagggccg aggagaaggc gtctccaagt 2500

 catttagtga tcatggtttc tattcccctt cctccacgct gggggactct 2550

 ccgttggttg atgacccctt ggagtatcag gctggcctcc tggtgcagaa 2600

 tgccattcaa caagccatag ccgagcaggt ggataaagct gtgtccaaaa 2650

 ccagcaggga tggagcagag caacagggac ctgaagcgac tgtagaggaa 2700

 gctgaagctg cggctttcgg ctcagaaaag cctcagagca tgtttgagcc 2750

 acctcaggtg tcttctcctg ttcaagagaa aagggatgta ttaccaaaga 2800

 ttctgcctgc tgaagacagg gcgctcaggg aaagggggcc cccccagcca 2850

 ctgccagctg tgcagcccag tggcccgatt aacatggagg agaccaggcc 2900

 cgaaggaagc tatttcagca agtactcgga ggcagctgag ctgagaagca 2950

 cagcctccct cctggccact caagaatctg acgtgatggt tgggcctttc 3000

 aagctgaggt ccaggaaaca gcggactttg tccatgattg aggaagagat 3050

 ccgagcagct caggaaaggg aagaggagct gaagaggcag agacaagtct 3100

 tgcagagtac gcagagcccc aggacaaaga atgccccatc actgccctcc 3150

 agaacatgct acaaaactgc tccagggaaa atagagaaag tcaaacctcc 3200

 tccatccccc accactgaag gccccagctt gcagcctgac ttagcccctg 3250

 aagaggctgc cggaacccag cggcccaaga atctgatgca gaccctcatg 3300

 gaagactatg agacacacaa atctaaaagg cgcgagagaa tggatgatag 3350

 tagttacact tctaagttac tgtcttgcaa ggtgacttcc gaggtcctcg 3400

 aggccacacg ggttaatcga agaaagagcg cactggcttt gcgctgggaa 3450

 gcagggatct atgccaacca ggaggaagaa gacaacgaat aaacttcctt 3500

 caacccagga agcgtctttg gtgcttggga gaccaagaaa ccaagaaatt 3550

 aacaactgaa agcattttaa tggactattt attaaagtgc aaacaaactc 3600

 agcaatcctt atgtagacca gaagctgcaa tatacaatga tgaaaatgaa 3650

 acgaaaagga agtcccccca tcagactctg gacacccagg aatcaaaaga 3700

 gaaaggactt ttttggtgac tcaatcccag tgtctggttt ggggccaatc 3750

 tacaatggat ccaaaaggac aaaacatgtt acaagcaaat caacatagtt 3800

 gctgcaggcg gaactgagac cagcctctct gggcgatgaa ggacaatggt 3850

 ggtagggcca cttagagagc agtagggccc aggctggtgc agcctacatg 3900

 gcacaggata tttccctgca ccagtttccc acctgtcact tgcagcatca 3950

 gagggtgttg cattaactcc attttctcca gcagccataa aatgaatggc 4000

 gtttctctcc atatttgccc agaagaggca gttatgattc cacttctcct 4050

 acatttaatt atttttaatt gagaacaact catgatcaca attcataaaa 4100

 tccatatttt aagacaatag ttcttcatgt cacaaacaca atctattcta 4150

 catgaggagg ctgagaaagg ggaagagaaa aacaaaccaa atggatgatg 4200

 ttagctttag gatcgtgtct gcttataata ttcactgatc tgcagtttat 4250

 gagaacacat tttcacagtt atgtttcttc ataggaaaac tatatttagt 4300

 gggcaacaac tatttttatg atgggatggg ggagtatata cacgtataga 4350

 atctgtacgc gttgaacaac ttggttcaag atggtggggg catttttaga 4400

 gcggcaataa ttgaaaaaaa aggcgaactc tgccttggag aggtagatga 4450

 taagaaataa aaaggtgttt ataactattt tgtattataa agtgggcctt 4500

 agagatagga agaagaatga tggattcctt ttggatcaat cagaaaggaa 4550

 acacgaaaga aaagtcagga aggtagagag agaaaaaggg agggaaggag 4600

 aaagaatggg aataaaataa ggaggtaaga gatactattt ttgctgagca 4650

 accagtgtgt ttcaggatga tacaaagaaa aatatagaat agaaataagt 4700

 gcaggcttgg aatcagctac aaatcctaaa gatggggtgt gtgtggatgt 4750

 gtgtgtgtgt gtgtgtacac cattgtgtgt ttgtaaaatg tgtatgttca 4800

 tgagtaaggg tgtgtgtgtg tgtgtattaa aattccagag tgaccgtggc 4850

 acttgggtgt acaggtaatt cctccagagc tgtttgctgg cttcaggagt 4900

 ggagtgagaa tttctttttt atgaaaaggg atataaaggc accgagctga 4950

 tgcagtattt gtaatattaa gttgacctaa caaggtattt gcatgagtca 5000

 caattacaaa gttttgagcg gttttgtaat ttgacattta ggagagtctc 5050

 ctatttattc tcatacttta cattcatgct tagtatacta tagaggatgc 5100

 cagctttaat ctttctgtca tttaaagcaa tatgataagg gtattcaata 5150

 attgggtgcc ctaaatttct ggatgagaaa attttcaatt ctggccatga 5200

 gaaagaaaaa aaaataaaca gccttctttt tttttccttt gttttaaaac 5250

 tgtggttttt taaaaaagca ataattaact cagacctcac taaaaatcat 5300

 ttttgttttt atattgttat gtcataagct ctattatgtt attctaacaa 5350

 gtagcaattt cacaaaattt gtatgtagat gttaacgcac atttcctttg 5400

 cttcttttat tagactagtg ttgactttgg ggggggacat ttattcacaa 5450

 atgagaagta ggcacaaagt aaaaaatgga accatctact aacaaggatc 5500

 ctttaaaact gccaagggag ctctaacttg aagccacatc ctacagatgg 5550

 cagcccaaat agcacatggg caattggcac catctttata tggttgagtc 5600

 tcctgaatat tttgaatgaa ttctcaacaa aatgtgctag ccactgggga 5650

 cgcaaaacaa gtaagatccc tgttgcaaga aattcatttt atagtgaggg 5700

 aggttggcat ggagactaaa attctcagga aaatgagatc cgtgttagat 5750

 tagaagtcct gatgtgaaat gggaggactc aggaaggagg atcgtcttta 5800

 cctgaggatt tctagccaga ggtcccagat gcctgggctg agaacccagc 5850

 gataaggggg cgttcccaaa gcagacacag ggataagaac agaggaggca 5900

 gcagcattgc acagccccag gcacagtggc agttaggatg gctggagagt 5950

 aggatagttc tatgggttgc ccaaaaaatg tgatgcgctt catgttttct 6000

 ctgactcatg gatctggtag agaccataga catgatatag actaacttcc 6050

 ccatttttca caagaggaaa ccatccttat gacttacctt aaagtttttt 6100

 gttctgtttt gaaggaaacc atgtgcttca tgaaacctac agttgacaag 6150

 agaatgtaca gctaagagaa aagcttaaga ggccacacta ttcgcggaat 6200

 ggctttagag gcagatgaag tggtctttga ccacagttga ttgaaccaga 6250

 gcacttattg cttaaagaat aacagagttc tagagctggg ggttcttggg 6300

 ccatgctccg tgtgtggata aggaaagaaa tactgtttct gggactctcc 6350

 cacagtcaca aagctgtttt cactgtggcc cctacatctc ttaacttttg 6400

 ctattactcc tatgctgcct tccggattac tgctgtctat cttcttgctc 6450

 cactcactga agatcctatt ataatcccat gaaaatgtaa attacagttt 6500

 acttgggaga gccagatttt ctctgtgctc ttgagttttt tattcattca 6550

 agaaaccttg ggccaccgct ttgtacatag caccgtgcta ggctctggga 6600

 tcccaaatgg acccttttaa ctttctgaag atgggaccgt cccctggagg 6650

 aaagtcattc ctgcctaatc catcgagaga aagaggctta cgaaaaactt 6700

 tgcctctgat gctcagcccc acccccaaat agcacacaag cttgttaacc 6750

 ccacctctta caaaatgttt agattctgta ggtgttaaaa gcctttctgg 6800

 aagtattgca ttctgccgtg tttataggtg ttcactttcc tccagagctg 6850

 attaactact gacatgactt ggctttctca tccagaaatt atggaaacag 6900

 ggtctgtcag tggcaggagg ccgtgctgtg ttttacttgg atgacacaat 6950

 gcagtttact tgcctcttca tacccatgca tgctgctcac cctagacaat 7000

 gacatataag ccgtatatag atcaatgtcc acatatatat acacacacac 7050

 atatatatat ataaagtgta acaaggaaca ctaaaacagt gttgattctt 7100

 gtctctgaag acaaataatt aaaccttttt tttcccaact aaagaatgga 7150

 tttaattaaa ctatgtattg aaaaaaaagt agcctaagtg ttagagatgg 7200

 tgaatatatt ccattttagt taaagaacaa atttcctgaa ttttaagcat 7250

 tcagtgagct gccaattttg attttgtgtt gctctttacc caaattattt 7300

 tttctttgtt tttctttttt tgggggagga ggggaaaaaa gcagcaatac 7350

 tgtgtttgga aattatactc tgtatctggt tttcctgtgt atgttaacca 7400

 cttaaatgtt attatcctgc tttggtttta gagtgattgt gaggcattca 7450

 atgcaagtat acagttattt tctcattaaa atccaatgtg tgttgagttt 7500

 ttataaaaaa aaaaaaaaaa aa 7522

<210> 4404
<211> 1103
<212> PRT
<213> Homo sapien

<400> 4404
 Met Ala Glu Ala Glu Leu His Lys Glu Arg Leu Gln Ala Ile Ala
   1               5                  10                  15

 Glu Lys Arg Lys Arg Gln Thr Glu Ile Glu Gly Lys Arg Gln Gln
                  20                  25                  30

 Leu Asp Glu Gln Ile Leu Leu Leu Gln His Ser Lys Ser Lys Val
                  35                  40                  45

 Leu Arg Glu Lys Trp Leu Leu Gln Gly Ile Pro Ala Gly Thr Ala
                  50                  55                  60

 Glu Glu Glu Glu Ala Arg Arg Arg Gln Ser Glu Glu Asp Glu Phe
                  65                  70                  75

 Arg Val Lys Gln Leu Glu Asp Asn Ile Gln Arg Leu Glu Gln Glu
                  80                  85                  90

 Ile Gln Thr Leu Glu Ser Glu Glu Ser Gln Ile Ser Ala Lys Glu
                  95                 100                 105

 Gln Ile Ile Leu Glu Lys Leu Lys Glu Thr Glu Lys Ser Phe Lys
                 110                 115                 120

 Asp Phe Gln Lys Gly Phe Ser Ser Thr Asp Gly Asp Ala Val Asn
                 125                 130                 135

 Tyr Ile Ser Ser Gln Leu Pro Asp Leu Pro Ile Leu Cys Ser Arg
                 140                 145                 150

 Thr Ala Glu Pro Ser Pro Gly Gln Asp Gly Thr Ser Arg Ala Ala
                 155                 160                 165

 Gly Val Gly Trp Glu Asn Val Leu Leu Lys Glu Gly Glu Ser Ala
                 170                 175                 180

 Ser Asn Ala Thr Glu Thr Ser Gly Pro Asp Met Thr Ile Lys Lys
                 185                 190                 195

 Pro Pro Gln Leu Ser Glu Asp Asp Ile Trp Leu Lys Ser Glu Gly
                 200                 205                 210

 Asp Asn Tyr Ser Ala Thr Leu Leu Glu Pro Ala Ala Ser Ser Leu
                 215                 220                 225

 Ser Pro Asp His Lys Asn Met Glu Ile Glu Val Ser Val Ala Glu
                 230                 235                 240

 Cys Lys Ser Val Pro Gly Ile Thr Ser Thr Pro His Pro Met Asp
                 245                 250                 255

 His Pro Ser Ala Phe Tyr Ser Pro Pro His Asn Gly Leu Leu Thr
                 260                 265                 270

 Asp His His Glu Ser Leu Asp Asn Asp Val Ala Arg Glu Ile Arg
                 275                 280                 285

 Tyr Leu Asp Glu Val Leu Glu Ala Asn Cys Cys Asp Ser Ala Val
                 290                 295                 300

 Asp Gly Thr Tyr Asn Gly Thr Ser Ser Pro Glu Pro Gly Ala Val
                 305                 310                 315

 Val Leu Val Gly Gly Leu Ser Pro Pro Val His Glu Ala Thr Gln
                 320                 325                 330

 Pro Glu Pro Thr Glu Arg Thr Ala Ser Arg Gln Ala Pro Pro His
                 335                 340                 345

 Ile Glu Leu Ser Asn Ser Ser Pro Asp Pro Met Ala Glu Ala Glu
                 350                 355                 360

 Arg Thr Asn Gly His Ser Pro Ser Gln Pro Arg Asp Ala Leu Gly
                 365                 370                 375

 Asp Ser Leu Gln Val Pro Val Ser Pro Ser Ser Thr Thr Ser Ser
                 380                 385                 390

 Arg Cys Ser Ser Arg Asp Gly Glu Phe Thr Leu Thr Thr Leu Lys
                 395                 400                 405

 Lys Glu Ala Lys Phe Glu Leu Arg Ala Phe His Glu Asp Lys Lys
                 410                 415                 420

 Pro Ser Lys Leu Phe Glu Asp Asp Glu His Glu Lys Glu Gln Tyr
                 425                 430                 435

 Cys Ile Arg Lys Val Arg Pro Ser Glu Glu Met Leu Glu Leu Glu
                 440                 445                 450

 Lys Glu Arg Arg Glu Leu Ile Arg Ser Gln Ala Val Lys Lys Asn
                 455                 460                 465

 Pro Gly Ile Ala Ala Lys Trp Trp Asn Pro Pro Gln Glu Lys Thr
                 470                 475                 480

 Ile Glu Glu Gln Leu Asp Glu Glu His Leu Glu Ser His Lys Lys
                 485                 490                 495

 Tyr Lys Glu Arg Lys Glu Arg Arg Ala Gln Gln Glu Gln Leu Leu
                 500                 505                 510

 Leu Gln Lys Gln Leu Gln Gln Gln Gln Gln Gln Pro Pro Ser Gln
                 515                 520                 525

 Leu Cys Thr Ala Pro Ala Ser Ser His Glu Arg Ala Ser Met Ile
                 530                 535                 540

 Asp Lys Ala Lys Glu Asp Ile Val Thr Glu Gln Ile Asp Phe Ser
                 545                 550                 555

 Ala Ala Arg Lys Gln Phe Gln Leu Met Glu Asn Ser Arg Gln Ala
                 560                 565                 570

 Val Ala Lys Gly Gln Ser Thr Pro Arg Leu Phe Ser Ile Lys Pro
                 575                 580                 585

 Phe Tyr Arg Pro Leu Gly Ser Val Asn Ser Asp Lys Pro Leu Thr
                 590                 595                 600

 Asn Pro Arg Pro Pro Ser Val Gly Gly Pro Pro Glu Asp Ser Gly
                 605                 610                 615

 Ala Ser Ala Ala Lys Gly Gln Lys Ser Pro Gly Ala Leu Glu Thr
                 620                 625                 630

 Pro Ser Ala Ala Gly Ser Gln Gly Asn Thr Ala Ser Gln Gly Lys
                 635                 640                 645

 Glu Gly Pro Tyr Ser Glu Pro Ser Lys Arg Gly Pro Leu Ser Lys
                 650                 655                 660

 Leu Trp Ala Glu Asp Gly Glu Phe Thr Ser Ala Arg Ala Val Leu
                 665                 670                 675

 Thr Val Val Lys Asp Asp Asp His Gly Ile Leu Asp Gln Phe Ser
                 680                 685                 690

 Arg Ser Val Asn Val Ser Leu Thr Gln Glu Glu Leu Asp Ser Gly
                 695                 700                 705

 Leu Asp Glu Leu Ser Val Arg Ser Gln Asp Thr Thr Val Leu Glu
                 710                 715                 720

 Thr Leu Ser Asn Asp Phe Ser Met Asp Asn Ile Ser Asp Ser Gly
                 725                 730                 735

 Ala Ser Asn Glu Thr Thr Asn Ala Leu Gln Glu Asn Ser Leu Ala
                 740                 745                 750

 Asp Phe Ser Leu Pro Gln Thr Pro Gln Thr Asp Asn Pro Ser Glu
                 755                 760                 765

 Gly Arg Gly Glu Gly Val Ser Lys Ser Phe Ser Asp His Gly Phe
                 770                 775                 780

 Tyr Ser Pro Ser Ser Thr Leu Gly Asp Ser Pro Leu Val Asp Asp
                 785                 790                 795

 Pro Leu Glu Tyr Gln Ala Gly Leu Leu Val Gln Asn Ala Ile Gln
                 800                 805                 810

 Gln Ala Ile Ala Glu Gln Val Asp Lys Ala Val Ser Lys Thr Ser
                 815                 820                 825

 Arg Asp Gly Ala Glu Gln Gln Gly Pro Glu Ala Thr Val Glu Glu
                 830                 835                 840

 Ala Glu Ala Ala Ala Phe Gly Ser Glu Lys Pro Gln Ser Met Phe
                 845                 850                 855

 Glu Pro Pro Gln Val Ser Ser Pro Val Gln Glu Lys Arg Asp Val
                 860                 865                 870

 Leu Pro Lys Ile Leu Pro Ala Glu Asp Arg Ala Leu Arg Glu Arg
                 875                 880                 885

 Gly Pro Pro Gln Pro Leu Pro Ala Val Gln Pro Ser Gly Pro Ile
                 890                 895                 900

 Asn Met Glu Glu Thr Arg Pro Glu Gly Ser Tyr Phe Ser Lys Tyr
                 905                 910                 915

 Ser Glu Ala Ala Glu Leu Arg Ser Thr Ala Ser Leu Leu Ala Thr
                 920                 925                 930

 Gln Glu Ser Asp Val Met Val Gly Pro Phe Lys Leu Arg Ser Arg
                 935                 940                 945

 Lys Gln Arg Thr Leu Ser Met Ile Glu Glu Glu Ile Arg Ala Ala
                 950                 955                 960

 Gln Glu Arg Glu Glu Glu Leu Lys Arg Gln Arg Gln Val Leu Gln
                 965                 970                 975

 Ser Thr Gln Ser Pro Arg Thr Lys Asn Ala Pro Ser Leu Pro Ser
                 980                 985                 990

 Arg Thr Cys Tyr Lys Thr Ala Pro Gly Lys Ile Glu Lys Val Lys
                 995                1000                1005

 Pro Pro Pro Ser Pro Thr Thr Glu Gly Pro Ser Leu Gln Pro Asp
                1010                1015                1020

 Leu Ala Pro Glu Glu Ala Ala Gly Thr Gln Arg Pro Lys Asn Leu
                1025                1030                1035

 Met Gln Thr Leu Met Glu Asp Tyr Glu Thr His Lys Ser Lys Arg
                1040                1045                1050

 Arg Glu Arg Met Asp Asp Ser Ser Tyr Thr Ser Lys Leu Leu Ser
                1055                1060                1065

 Cys Lys Val Thr Ser Glu Val Leu Glu Ala Thr Arg Val Asn Arg
                1070                1075                1080

 Arg Lys Ser Ala Leu Ala Leu Arg Trp Glu Ala Gly Ile Tyr Ala
                1085                1090                1095

 Asn Gln Glu Glu Glu Asp Asn Glu
                1100

<210> 4405
<211> 1720
<212> DNA
<213> Homo sapien

<400> 4405
 gagaagacca gggaagaagc agaacttgag gccaacagtg tgtttcgtca 50

 aaaggtagaa atgtcctacc agcggatgga gaatcctggc tgccatgtgg 100

 ttgatgccag cccctccaga gaaaaggtcc tgcagacggt attaagccta 150

 atccagaata gttttagtga accgtagtta ctctggccag gtgccacgtc 200

 taactagatt agatgttgtt tgaaacatct acatccacca tttgttatgc 250

 agtgttccca aatttctgtt ctacaagcat gttgtgtggc agaaaactgg 300

 agaccaggca tcttaatttt acttcagcca tcgtaccctc ttctgactga 350

 tggacccgtc atcacaaagg tccctctcat catgttccag tgagaggcca 400

 gcgattgctt tcttcctggc atagtaaaca ttttcttgga acatatgttt 450

 cacttaatca ctaccaaata tctggaagac ctgtcttact cagacagcac 500

 caggtgtaca gaagcagcag acaagatctt ccagatcagc agggagaccc 550

 cggagcctct gcttctccta cactggcatg ctgatgagat cgtgacatgc 600

 ccacattggc ttcttccaca tctggttgca ctcgtcatga tgggctcgct 650

 gcatctccct cagtcccaaa ttctagagcc aagtgttcct gcagaggctg 700

 tctatgtgtc ctggctgccc aaggacactc ctgcagagcc atttttgggt 750

 aaggaacact tacaaagaag gcattgatct tgtgtctgag gctcagagcc 800

 cttttgatag gcttctgagt catatataaa gacattcaag ccaagatgct 850

 ccaactgcaa atataccaac cttctctgaa ttatattttg cttatttata 900

 tttcttttct ttttttctaa agtatggctc tgaatagaat gcacattttc 950

 cattgaactg gatgcatttc atttagccaa tccagtaatt tatttatatt 1000

 aatctataca taatatgttt cctcagcata ggagctatga ttcattaatt 1050

 aaaagtggag tcaaaacgct aaatgcaatg tttgttgtgt attttcatta 1100

 cacaaactta atttgtcttg ttaaataagt acagtggatc ttggagtggg 1150

 atttcttggt aaattatctt gcacttgaat gtctcatgat tacatatgaa 1200

 atcgctttga catatcttta gacagaaaaa agtagctgag tgagggggaa 1250

 attatagagc tgtgtgactt tagggagtag gttgaaccag gtgattacct 1300

 aaaattcctt ccagttcaaa ggcagataaa tctgtaaatt attttatcct 1350

 atctaccatt tcttaagaag acattactcc aaaataatta aatttaaggc 1400

 tttatcaggt ctgcatatag aatcttaaat tctaataaag tttcatgtta 1450

 atgtcatagg atttttaaaa gagctatagg taatttctgt ataatatgtg 1500

 tatattaaaa tgtaattgat ttcagttgaa agtattttaa agctgataaa 1550

 tagcattagg gttctttgca atgtggtatc tagctgtatt attggtttta 1600

 tttactttaa acattttgaa aagcttatac tggcagccta gaaaaacaaa 1650

 caattaatgt atctttatgt ccctggcaca tgaataaact ttgctgtggt 1700

 ttactaaaaa aaaaaaaaaa 1720

<210> 4406
<211> 58
<212> PRT
<213> Homo sapien

<400> 4406
 Glu Lys Thr Arg Glu Glu Ala Glu Leu Glu Ala Asn Ser Val Phe
   1               5                  10                  15

 Arg Gln Lys Val Glu Met Ser Tyr Gln Arg Met Glu Asn Pro Gly
                  20                  25                  30

 Cys His Val Val Asp Ala Ser Pro Ser Arg Glu Lys Val Leu Gln
                  35                  40                  45

 Thr Val Leu Ser Leu Ile Gln Asn Ser Phe Ser Glu Pro
                  50                  55

<210> 4407
<211> 1198
<212> DNA
<213> Homo sapien

<400> 4407
 gccgcatcca ggcgagcggg cagcctttgt ggcctatgcc ttggcttttc 50

 cccgggcctt ccagggcctc ctggacacct acagcgtgtg gaggagtggt 100

 ctccccaact tcctagcagt cgccctggcc ctgggagagc tgggctaccg 150

 ggcagtgggc gtgaggctgg acagtggtga cctgctacag caggctcagg 200

 agatccgcaa ggtcttccga gctgctgcag cccagtgagt ttcccgggga 250

 ggaggtgtgc ctggtgggag atccccgggg tttgggaatg ggcagggaag 300

 gacagtgagg tactctgctg aagtttcagc ggtgatactg taggccgtgg 350

 cagggaagta agtggtgggg ctccctagga gctcccaagc agaaggtgag 400

 cacaggtgtc cttgactgag gcggggcggg gagcaggggg acaccagggt 450

 gaatcaggaa gacccgaggg gtggccccca ccctttctcc acccacgcgg 500

 caggttccag gtgccctggc tggagtcagt cctcatcgta gtcagcaaca 550

 acattgacga ggaggcgctg gcccgactgg cccaggaggg cagtgaggtg 600

 aatgtcattg gcattggcac cagtgtggtc acctgccccc aacagccttc 650

 cctgggtggt gtctataagc tggtggccgt ggggggccag ccacgaatga 700

 agctgaccga ggaccccgag aagcagacgt tgcctgggag caaggctgct 750

 ttccggctcc tgggctctga cgggtctcca ctcatggaca tgctgcagtt 800

 agcagaagag ccagtgccac aggctgggca ggagctgagg gtgtggcctc 850

 caggggccca ggagccctgc accgtgaggc cagcccaggt ggagccacta 900

 ctgcggctct gcctccagca gggacagctg tgtgagccgc tcccatccct 950

 ggcagagtat agagccttgg cccagctgtc cctgagccga ctcagccctg 1000

 agcacaggcg gctgcggagc cctgcccagt accaggtggt gctgtccgaa 1050

 aggctgcagg ccctggtgaa cagtctgtgt gcggggcagt ccccctgaga 1100

 ctcggagcgg ggctgactgg aaacaacacg aatcactcac ttttccccaa 1150

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1198

<210> 4408
<211> 133
<212> PRT
<213> Homo sapien

<400> 4408
 Met Lys Leu Thr Glu Asp Pro Glu Lys Gln Thr Leu Pro Gly Ser
   1               5                  10                  15

 Lys Ala Ala Phe Arg Leu Leu Gly Ser Asp Gly Ser Pro Leu Met
                  20                  25                  30

 Asp Met Leu Gln Leu Ala Glu Glu Pro Val Pro Gln Ala Gly Gln
                  35                  40                  45

 Glu Leu Arg Val Trp Pro Pro Gly Ala Gln Glu Pro Cys Thr Val
                  50                  55                  60

 Arg Pro Ala Gln Val Glu Pro Leu Leu Arg Leu Cys Leu Gln Gln
                  65                  70                  75

 Gly Gln Leu Cys Glu Pro Leu Pro Ser Leu Ala Glu Tyr Arg Ala
                  80                  85                  90

 Leu Ala Gln Leu Ser Leu Ser Arg Leu Ser Pro Glu His Arg Arg
                  95                 100                 105

 Leu Arg Ser Pro Ala Gln Tyr Gln Val Val Leu Ser Glu Arg Leu
                 110                 115                 120

 Gln Ala Leu Val Asn Ser Leu Cys Ala Gly Gln Ser Pro
                 125                 130

<210> 4409
<211> 948
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 156-239
<223> Unknown base

<400> 4409
 aaaatgtgtc tctttaaaga aaaagactat aggaactcca acagtactgt 50

 gttccaaaca gtgtgagaaa acaagaaatg tattttaata tatatataat 100

 gtttacaaat gaatgatttt caaatacagt tgttaattct caggtatttg 150

 aagcannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc ttgtttaaga 250

 tcacacagct agtgcagtta ccccctctca gtaattatgt ttggcaaata 300

 tgaaatacaa ggatctggca aggttaggaa gaggttaaga atatcagtga 350

 cagtactctg aggcatctgg gcatgtcaga tgaagattta ttattcagaa 400

 aagttaagtc agctgttgca gggatcagtt gttttattcc tggaaaatgt 450

 ttttcatttt gctgcaaatc tatatctgac ctgctgagga aatcgtttgg 500

 tgaaatgaat ccagaaagca gagaaaatgc ttcattactt taaatagcag 550

 cattaagccc attatagcct ctgaattgtc ccttccttga gtttgctaat 600

 gcttccaact tagtcatttg aagcccaaga gtctaatttt atatgccctg 650

 ccaatgtcct catctattgc agaatgtata attatctatt tgttttggac 700

 tatatgttac aaaaatttaa aacataagat cctctctcta tatttcatta 750

 ttggtgaacc cacattgtgc tgtgttttgt gatattttat cattttctag 800

 attcttatgt ggatctaata acgaccactt gaacccagtt tcacagaatc 850

 cttatttttc tgttcaaatt aggaattagg gacatgggat ggaaattggg 900

 aaatccttcc attctccagt aaactatcgc aaggacaaaa aaccaaac 948

<210> 4410
<211> 64
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 16-44
<223> unknown amino acid

<220>
<221> Unsure
<222> 156-239
<223> Unknown amino acid

<400> 4410
 Met Asn Asp Phe Gln Ile Gln Leu Leu Ile Leu Arg Tyr Leu Lys
   1               5                  10                  15

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Leu
                  35                  40                  45

 Phe Lys Ile Thr Gln Leu Val Gln Leu Pro Pro Leu Ser Asn Tyr
                  50                  55                  60

 Val Trp Gln Ile


<210> 4411
<211> 3789
<212> DNA
<213> Homo sapien

<400> 4411
 aaagagcagg cgaaagccac ggcgtctgcg tttgcaatgc atgctggtcc 50

 gtgtagttct cagcctgaca ccgtcgttcc cagaacccag cgcgctctgt 100

 gctggcgggc gcagaggcct cccaggagga gagcaaggac ctggcagggg 150

 ctgctgagga ggagagcggg ctgcccgggg ccgggcctgg ctcctgtgct 200

 tttggggagg agattcccat ggatggggag cctcctgcct cctcgggcct 250

 ggggctccca gactacacgt ctggcgtcag cttccacgac caggctgacc 300

 tccctgagac agaggacttc caagccgggc tctatgtgac tgagtctccc 350

 cagccccagg aggctgaggc tgtgagcctg ggccggctga gtgacaagag 400

 cagcaccagc gagacctccc tgggtgagga gcgggctcca gacgaggggg 450

 gtgcccccgt ggacaagagc agccttcgat caggtgacag cagccaggac 500

 ttgaagcaaa gcgagggctc cgaggaggaa gaggaggagg aggacagctg 550

 cgtggtgcta gaggaggagg agggggagca ggaggaggtc accggggcat 600

 ctgagctcac tctgtctgac acggtgctgt ccatggagac ggttgtggcc 650

 ggcggcagtg ggggagatgg agaagaagag gaggaggcac tgcctgagca 700

 gtcagaaggc aaagaacaga agatcctcct tgatacagcc tgcaagatgg 750

 tccgctggct gtctgccaag ctcggcccca cagtggcctc tcgccacgtg 800

 gcccggaacc tgctccgcct gctgacgtct tgttatgttg gacccactcg 850

 gcagcagttc acagtgagca gtggcgagag cccaccgctg agcgccggca 900

 acatctacca gaagaggccg gtcctgggcg acatcgtgtc agggcctgtg 950

 ctcagctacc tcctccacat cgcccgcctg tatggggagc ctgtcctcac 1000

 ctaccagtac ctgccctaca tcagctacct ggtggcccca gggagtgcct 1050

 caggccccag ccgactgaac agccgtaagg aggcggggct gctggccgcg 1100

 gtgacgctga ctcagaagat catcgtgtac ctctcagaca ccacactcat 1150

 ggacatcctg ccccggatca gccatgaggt cctgctgccc gtgctcagct 1200

 tcctcacctc cctcgtcacg gggttcccaa gtggggccca ggctcggacc 1250

 atcctgtgtg tgaaaaccat cagcctcatc gccctcatct gcctgcgcat 1300

 tggacaggag atggtccagc agcacctgag cgagcccgtg gccacctttt 1350

 tccaggtctt ctctcagctg catgagcttc ggcaacagga tctgaagctg 1400

 gaccctgcgg gccgtggtga gggccagctg ccacaggtgg tcttctctga 1450

 tgggcagcag cggcccgtgg accccgccct gctggacgag ctgcagaagg 1500

 tgttcaccct ggagatggca tacacaatct acgtgccctt ctcctgcctg 1550

 ttgggtgaca tcatccggaa aatcatcccc aaccacgagc tggttgggga 1600

 gctggcggcg ctgtacttgg agagcatcag ccccagcagt cgcaaccctg 1650

 ccagcgtgga gcccaccatg cccggcaccg ggcccgagtg ggacccccat 1700

 ggtgggggct gccctcagga tgacggccac tcagggacct ttgggagcgt 1750

 cctggtgggg aaccgcattc agatccccaa tgactctcgg cctgagaacc 1800

 ccggaccact gggccccatc tcgggggtgg gtggcggggg cctgggcagc 1850

 gggagcgacg acaacgccct gaagcaggag ctgccgcgga gcgtgcacgg 1900

 gctgagcgga aactggctgg cgtactggca gtacgagatc ggcgtgagcc 1950

 agcaggatgc ccactttcac ttccaccaga tccgcctgca gagcttcccg 2000

 ggccactcgg gggccgtcaa gtgcgtggca cccctgagca gcgaggactt 2050

 cttcctgagc ggcagcaagg atcgtaccgt gcgcctctgg ccgctgtaca 2100

 actacggcga cgggaccagc gagacggccc cacgcctcgt ctacacccag 2150

 caccgcaaga gcgtcttctt cgtgggccag cttgaggccc cacagcacgt 2200

 ggtgagctgt gacggggctg tgcacgtctg ggaccccttc acagggaaga 2250

 cccttcgcac agtggagccg ctggacagcc gggtgcccct gactgcggtg 2300

 gctgtcatgc ccgcccccca caccagcatc accatggcca gcactgactc 2350

 taccctgcgc tttgtggact gcaggaagcc tggtctgcag tacgagttcc 2400

 gactgggcgg tgggctgaac cctgggcttg tccgtgccct ggccatcagc 2450

 cccagtggcc gtagtgtcgt ggccggcttc tcctcaggct tcatggtgct 2500

 cctggacacc cgcacgggcc tggttctgcg aggctggcca gcccacgagg 2550

 gggacattct gcagatcaag gcggtggagg gcagcgtcct ggtcagctcc 2600

 tcctctgacc attccttgac cgtctggaag gagctggagc agaagcccac 2650

 ccatcactac aagtcagcat ccgaccccat ccacaccttt gacctgtacg 2700

 gcagtgaggt ggtcactggc accgtgtcca acaagattgg cgtctgctcc 2750

 ctgcttgagc caccctcgca ggccaccacg aagctcagct ctgagaactt 2800

 ccgcggcacg ctcaccagcc tggccttgct gcccactaaa cgccacctcc 2850

 tgctgggctc agacaacggg gttatccgcc tcctggcata gactgaggca 2900

 ggagctggcc gggcaagggt gggaagacat ctgcgggcgc gtgtccgctc 2950

 accctgttcc ctgagcagca gctccctcca gggaggccct gggtcccacg 3000

 ccctgggtgc ccacatggcc tgccaactag ggcctgcaaa tggagtgggg 3050

 gagtcctggc ccctgaatca ccagagccac caagcctgcc agaggggtcc 3100

 cattcatggc ttggggacac agggctccta gcaagcagga agttaagagc 3150

 aggaggaagc gttgctacct tcacttctcc ccagctctgc cctctgggtc 3200

 cacatgagga cagggaagct cgggaagggg aagggagact ggccctgccc 3250

 agccggtctc tagcccctca gcccccgctg ggcactctct gtcccatccc 3300

 tctaggacag ggaagctggc ctggtccagg gcactgatgg tgcttggatt 3350

 ccagcctaag gaaggctggc cgtggtccag gagttaaggg cttgggtctg 3400

 gggtttaagt ggccacccat ccaggccctg gccagtgtgg gaccgggacg 3450

 ggaaggaaga aggaggctag gagcaggggg aaaaggtgca cttggccagt 3500

 ggcgcctgcc aggagtgagt ccatgcgttg tctgcccacc cctaccacag 3550

 tgtttgtgcc ttcagctgag ggggcagcct ctgggccctg aacccctgct 3600

 ggggctccac gaccctgaga gaagggttga gaagaatcat ctctgcacct 3650

 cgggtctctg ccagaggaag acttaagcat ccctgcgacc tcacattcta 3700

 gacagagatg aggtccaagg gttggcccct gctgccttct cacaatttgc 3750

 aatagatgta aataggacca ataaatcctt tggaagagc 3789

<210> 4412
<211> 890
<212> PRT
<213> Homo sapien

<400> 4412
 Met Asp Gly Glu Pro Pro Ala Ser Ser Gly Leu Gly Leu Pro Asp
   1               5                  10                  15

 Tyr Thr Ser Gly Val Ser Phe His Asp Gln Ala Asp Leu Pro Glu
                  20                  25                  30

 Thr Glu Asp Phe Gln Ala Gly Leu Tyr Val Thr Glu Ser Pro Gln
                  35                  40                  45

 Pro Gln Glu Ala Glu Ala Val Ser Leu Gly Arg Leu Ser Asp Lys
                  50                  55                  60

 Ser Ser Thr Ser Glu Thr Ser Leu Gly Glu Glu Arg Ala Pro Asp
                  65                  70                  75

 Glu Gly Gly Ala Pro Val Asp Lys Ser Ser Leu Arg Ser Gly Asp
                  80                  85                  90

 Ser Ser Gln Asp Leu Lys Gln Ser Glu Gly Ser Glu Glu Glu Glu
                  95                 100                 105

 Glu Glu Glu Asp Ser Cys Val Val Leu Glu Glu Glu Glu Gly Glu
                 110                 115                 120

 Gln Glu Glu Val Thr Gly Ala Ser Glu Leu Thr Leu Ser Asp Thr
                 125                 130                 135

 Val Leu Ser Met Glu Thr Val Val Ala Gly Gly Ser Gly Gly Asp
                 140                 145                 150

 Gly Glu Glu Glu Glu Glu Ala Leu Pro Glu Gln Ser Glu Gly Lys
                 155                 160                 165

 Glu Gln Lys Ile Leu Leu Asp Thr Ala Cys Lys Met Val Arg Trp
                 170                 175                 180

 Leu Ser Ala Lys Leu Gly Pro Thr Val Ala Ser Arg His Val Ala
                 185                 190                 195

 Arg Asn Leu Leu Arg Leu Leu Thr Ser Cys Tyr Val Gly Pro Thr
                 200                 205                 210

 Arg Gln Gln Phe Thr Val Ser Ser Gly Glu Ser Pro Pro Leu Ser
                 215                 220                 225

 Ala Gly Asn Ile Tyr Gln Lys Arg Pro Val Leu Gly Asp Ile Val
                 230                 235                 240

 Ser Gly Pro Val Leu Ser Tyr Leu Leu His Ile Ala Arg Leu Tyr
                 245                 250                 255

 Gly Glu Pro Val Leu Thr Tyr Gln Tyr Leu Pro Tyr Ile Ser Tyr
                 260                 265                 270

 Leu Val Ala Pro Gly Ser Ala Ser Gly Pro Ser Arg Leu Asn Ser
                 275                 280                 285

 Arg Lys Glu Ala Gly Leu Leu Ala Ala Val Thr Leu Thr Gln Lys
                 290                 295                 300

 Ile Ile Val Tyr Leu Ser Asp Thr Thr Leu Met Asp Ile Leu Pro
                 305                 310                 315

 Arg Ile Ser His Glu Val Leu Leu Pro Val Leu Ser Phe Leu Thr
                 320                 325                 330

 Ser Leu Val Thr Gly Phe Pro Ser Gly Ala Gln Ala Arg Thr Ile
                 335                 340                 345

 Leu Cys Val Lys Thr Ile Ser Leu Ile Ala Leu Ile Cys Leu Arg
                 350                 355                 360

 Ile Gly Gln Glu Met Val Gln Gln His Leu Ser Glu Pro Val Ala
                 365                 370                 375

 Thr Phe Phe Gln Val Phe Ser Gln Leu His Glu Leu Arg Gln Gln
                 380                 385                 390

 Asp Leu Lys Leu Asp Pro Ala Gly Arg Gly Glu Gly Gln Leu Pro
                 395                 400                 405

 Gln Val Val Phe Ser Asp Gly Gln Gln Arg Pro Val Asp Pro Ala
                 410                 415                 420

 Leu Leu Asp Glu Leu Gln Lys Val Phe Thr Leu Glu Met Ala Tyr
                 425                 430                 435

 Thr Ile Tyr Val Pro Phe Ser Cys Leu Leu Gly Asp Ile Ile Arg
                 440                 445                 450

 Lys Ile Ile Pro Asn His Glu Leu Val Gly Glu Leu Ala Ala Leu
                 455                 460                 465

 Tyr Leu Glu Ser Ile Ser Pro Ser Ser Arg Asn Pro Ala Ser Val
                 470                 475                 480

 Glu Pro Thr Met Pro Gly Thr Gly Pro Glu Trp Asp Pro His Gly
                 485                 490                 495

 Gly Gly Cys Pro Gln Asp Asp Gly His Ser Gly Thr Phe Gly Ser
                 500                 505                 510

 Val Leu Val Gly Asn Arg Ile Gln Ile Pro Asn Asp Ser Arg Pro
                 515                 520                 525

 Glu Asn Pro Gly Pro Leu Gly Pro Ile Ser Gly Val Gly Gly Gly
                 530                 535                 540

 Gly Leu Gly Ser Gly Ser Asp Asp Asn Ala Leu Lys Gln Glu Leu
                 545                 550                 555

 Pro Arg Ser Val His Gly Leu Ser Gly Asn Trp Leu Ala Tyr Trp
                 560                 565                 570

 Gln Tyr Glu Ile Gly Val Ser Gln Gln Asp Ala His Phe His Phe
                 575                 580                 585

 His Gln Ile Arg Leu Gln Ser Phe Pro Gly His Ser Gly Ala Val
                 590                 595                 600

 Lys Cys Val Ala Pro Leu Ser Ser Glu Asp Phe Phe Leu Ser Gly
                 605                 610                 615

 Ser Lys Asp Arg Thr Val Arg Leu Trp Pro Leu Tyr Asn Tyr Gly
                 620                 625                 630

 Asp Gly Thr Ser Glu Thr Ala Pro Arg Leu Val Tyr Thr Gln His
                 635                 640                 645

 Arg Lys Ser Val Phe Phe Val Gly Gln Leu Glu Ala Pro Gln His
                 650                 655                 660

 Val Val Ser Cys Asp Gly Ala Val His Val Trp Asp Pro Phe Thr
                 665                 670                 675

 Gly Lys Thr Leu Arg Thr Val Glu Pro Leu Asp Ser Arg Val Pro
                 680                 685                 690

 Leu Thr Ala Val Ala Val Met Pro Ala Pro His Thr Ser Ile Thr
                 695                 700                 705

 Met Ala Ser Thr Asp Ser Thr Leu Arg Phe Val Asp Cys Arg Lys
                 710                 715                 720

 Pro Gly Leu Gln Tyr Glu Phe Arg Leu Gly Gly Gly Leu Asn Pro
                 725                 730                 735

 Gly Leu Val Arg Ala Leu Ala Ile Ser Pro Ser Gly Arg Ser Val
                 740                 745                 750

 Val Ala Gly Phe Ser Ser Gly Phe Met Val Leu Leu Asp Thr Arg
                 755                 760                 765

 Thr Gly Leu Val Leu Arg Gly Trp Pro Ala His Glu Gly Asp Ile
                 770                 775                 780

 Leu Gln Ile Lys Ala Val Glu Gly Ser Val Leu Val Ser Ser Ser
                 785                 790                 795

 Ser Asp His Ser Leu Thr Val Trp Lys Glu Leu Glu Gln Lys Pro
                 800                 805                 810

 Thr His His Tyr Lys Ser Ala Ser Asp Pro Ile His Thr Phe Asp
                 815                 820                 825

 Leu Tyr Gly Ser Glu Val Val Thr Gly Thr Val Ser Asn Lys Ile
                 830                 835                 840

 Gly Val Cys Ser Leu Leu Glu Pro Pro Ser Gln Ala Thr Thr Lys
                 845                 850                 855

 Leu Ser Ser Glu Asn Phe Arg Gly Thr Leu Thr Ser Leu Ala Leu
                 860                 865                 870

 Leu Pro Thr Lys Arg His Leu Leu Leu Gly Ser Asp Asn Gly Val
                 875                 880                 885

 Ile Arg Leu Leu Ala
                 890

<210> 4413
<211> 3718
<212> DNA
<213> Homo sapien

<400> 4413
 cggccgctgc ccgcaggagg aagccccggc cgccaccccc accgccggcg 50

 ccccccgagg agagctgccc ggccaagccc gtggcccccg ggccctgctt 100

 cgggggccgc accttggagg agatctggag ggcggccacc ccgacgctga 150

 ccaccttccc caccatccgc gtcggcagcg acgtgtgggg cgagcgcagc 200

 ctggcggcag cgcggcgcag ggcgcgccag gtcctgcgag tgaacctgga 250

 acccatggtg aggctccgcc gcttcccggt gccccgggca tgaggtgcgg 300

 cctccagggc gcctcctgcc ggccccgacc ttgggacagg ccttccgccc 350

 ggaggaatga acaagtgtca gtcgagtgtt tacagatccg gccaggaccc 400

 cggcccccaa tgcactttac gcgcgaagaa gttgccggat ggttgtccct 450

 gtcccgggcc gcggcgcggt cgtcttggac gctggggcag gtgtgccctc 500

 tgctgcctcc cgtacccggc ctgcggaggg aggggacagc tggacccgca 550

 ggggaggtcc ctttcttcct gaccaccgat tgagacgtct ccaggacctt 600

 aggggcagat ccgttttctc actgttggac tctacctcac tggtctggaa 650

 gtcctccgaa gacattattt ttccaaagga atttggtttc gtgcttgtgt 700

 aataaagcca gaatttactt gttctttatc tccccctttt tctatttcac 750

 tgtcacccct ctttgtggac agaagttcga acatgtggtg ttgcactagt 800

 ttgtgctcag ggtattctga agcccactcg tttcctaatt tttactggat 850

 tccaaagctt tgatcgagga tattttttaa gaggttcaag cttgtgactg 900

 ttagtagtgc aaggatttgt atgggctcag tgattacaaa caaagacatg 950

 caaaatacaa ctgtttaaac attttcaagg tatttttaaa ggttttgtat 1000

 tgaaacaatg tttatattta ctgagctcct aaaaatggta gaatacacat 1050

 gaaaactttt gtttaggaaa agttaacttg ttaaattctt ttgaattgaa 1100

 taaaaaaatg cattgaaacc atatggtgtg tgattgaaaa aaatgaatat 1150

 attgtgaaga actggtttgg ttacaggagt cactggaatc cgactggaga 1200

 tgatttggcc ccctgtcctg gtctaacata caaatctagg aatattatgc 1250

 gttaaagtat tttaaaatac attatccttg taatgtattt tacaaggata 1300

 atgtatttta aaatgggagt tgcataggag agatggatgt gtgtaaacat 1350

 tatcactaaa atgataaaca gaatacccat tagaattctt agaactatta 1400

 atgatcaaga ggggtggagg catttcttgg tatcaaataa ctggttaagg 1450

 ttactttggg cgaaatctat ttcctttttg tttttgttgt tggataacaa 1500

 gaaatgtcta gactaatatt catcagtttt acaaacataa tgaaaattag 1550

 ttgattttta gttgattttt ttgtcccaac atttttttta acctttttgc 1600

 cactcattat atgtttgcag ttctaggtct ttgacagctg aagaccacag 1650

 gaatcaaaca ggcgagacac acagaatact gacccttctt tacgctttta 1700

 tagtgtttat accatatggc ccagtgtgga attcttgatt atccaagtgc 1750

 ctttggtcat ttgtggcagg aaaacttaat agtttttagc cagcagtgcc 1800

 acagccagct tttactgcaa tacctaaagg gtcaagtagt gtttttgtac 1850

 cactattatt tcaaatttaa gtattctgcc atgaaacgat ccatactggg 1900

 ctggaacttg acatgtgaaa tctttaatac taaagcttat ctctgcttgg 1950

 cagcttttta ggagaataat gagagttaca attttgactc ttgcgttcct 2000

 agaattcaaa tggcatagct ttctgaaatg agtatttcaa gtttagtagt 2050

 ccgtatagga gtgttgtgac ttcaatttca gtgttcttgt taaaagaaat 2100

 aatatgatat atatatacac acatatatat aacttgatgc cagttttcta 2150

 gtaagcctca gtcttttatt cactactcaa tgataatgca ttgtacaaac 2200

 actgtcacat gagtaaataa aaatgaataa ttccttagaa gatggagagt 2250

 gttaaattat atttgtgata ggaagcttag acatatcttt tggttattag 2300

 cttccattgc caattgtatt tcagatgcat agggttttct tcccaaaaat 2350

 atattgttaa cttttatagc taactagcac ctggaaaaaa tgtatttgta 2400

 caactttact attgtatata gttttataat aatgaaaaat aaacccaatg 2450

 gccatattag aatgcaattt cgacatacag cttatctaga tagttttcca 2500

 gaggattttg aaatttggct taactgggag gataactgct cagcacacca 2550

 ctgaaacata accactgaca ccattcattt attttaactg agattcttga 2600

 catttttctc tcctatgcct tgttacttta gcatacttga actcacataa 2650

 atgcttcttt ggattacatg ggctatctga ttccattttg gatctgattg 2700

 tccatcttga attcaatatg gtattcatct ggactattca aaaattatgc 2750

 catttctagt ctgtgaaata agatgtaaaa aatctttatt tttgcccttt 2800

 ggtaaaaacc tatgtgacaa cttttaaaat gtgaagcaac atctaatata 2850

 gttgactggt atactaatag gaaagtgaaa gtatttcatg ggtactttgt 2900

 cacagaatgt gaaaagaaac ttggcatagt ggcctttata atgaggcatc 2950

 cacttactcc tctgaagtga agtctgtagc ttagcttgtg tatagttttt 3000

 gaaagaaatc tcatgatctt cgttcattct cttgccttct cttttatctc 3050

 atatggcaca agtagagggg gaagccagga ggaaattcat cacctcgcta 3100

 tgcttttatt tgatttttaa ttcctgagtg cctaaatgtg gtgaccggca 3150

 cctcacataa ctttttgaga ttcttgatgt catttttatc cttcctgtca 3200

 accagcaatg tatttttatg ttactaaaac cagtaacgtc ataattgttg 3250

 agggcaagct tcattgttga tagtgcaaag tgtcgctgtt gtgatgtgtg 3300

 tttattttat tcaagtttga atattgacaa gtgtaactta agctggtgac 3350

 tgacacctat tgatctgctg tgtgcaaatg atagtactat tttttagaaa 3400

 actcttaagt aaattttaaa aatatttgaa tacaaaatat ctgagcaatt 3450

 ttgaactcaa aagtttttca ttgttttaag gattgccaca ggactcttta 3500

 atggttttta atggacatac atgcctaata tttattggtg tgtttaaaat 3550

 attttttgat agagtgttat gtcttaagcg cattagaaaa caattgtttg 3600

 taatggaatc aaagtgtttc cctggacagt ttgatgtgct tatggttgag 3650

 atttataatc tgcttgtact ttgcttttta acttattaac tgtaaataaa 3700

 ttttagagaa tacataaa 3718

<210> 4414
<211> 193
<212> PRT
<213> Homo sapien

<400> 4414
 Gly Arg Cys Pro Gln Glu Glu Ala Pro Ala Ala Thr Pro Thr Ala
   1               5                  10                  15

 Gly Ala Pro Arg Gly Glu Leu Pro Gly Gln Ala Arg Gly Pro Arg
                  20                  25                  30

 Ala Leu Leu Arg Gly Pro His Leu Gly Gly Asp Leu Glu Gly Gly
                  35                  40                  45

 His Pro Asp Ala Asp His Leu Pro His His Pro Arg Arg Gln Arg
                  50                  55                  60

 Arg Val Gly Arg Ala Gln Pro Gly Gly Ser Ala Ala Gln Gly Ala
                  65                  70                  75

 Pro Gly Pro Ala Ser Glu Pro Gly Thr His Gly Glu Ala Pro Pro
                  80                  85                  90

 Leu Pro Gly Ala Pro Gly Met Arg Cys Gly Leu Gln Gly Ala Ser
                  95                 100                 105

 Cys Arg Pro Arg Pro Trp Asp Arg Pro Ser Ala Arg Arg Asn Glu
                 110                 115                 120

 Gln Val Ser Val Glu Cys Leu Gln Ile Arg Pro Gly Pro Arg Pro
                 125                 130                 135

 Pro Met His Phe Thr Arg Glu Glu Val Ala Gly Trp Leu Ser Leu
                 140                 145                 150

 Ser Arg Ala Ala Ala Arg Ser Ser Trp Thr Leu Gly Gln Val Cys
                 155                 160                 165

 Pro Leu Leu Pro Pro Val Pro Gly Leu Arg Arg Glu Gly Thr Ala
                 170                 175                 180

 Gly Pro Ala Gly Glu Val Pro Phe Phe Leu Thr Thr Asp
                 185                 190

<210> 4415
<211> 3063
<212> DNA
<213> Homo sapien

<400> 4415
 agcggggcag aagaggaaga tttctgaaga gtgcagctgc ctgaaccgag 50

 ccctgccgaa cagctgagaa ttgcactgca accatgagtg agaacaataa 100

 gaattccttg gagagcagcc tacggcaact aaaatgccat ttcacctgga 150

 acttgatgga gggagaaaac tccttggatg attttgaaga caaagtattt 200

 taccggactg agtttcagaa tcgtgaattc aaagccacaa tgtgcaacct 250

 actggcctat ctaaagcacc tcaaagggca aaacgaggca gccctggaat 300

 gcttacgtaa agctgaagag ttaatccagc aagagcatgc tgaccaggca 350

 gaaatcagaa gtctggtcac ctggggaaac tatgcctggg tctactatca 400

 catgggccga ctctcagacg ttcagattta tgtagacaag gtgagacatg 450

 tctgtgagaa gttttccagt ccctatagaa ttgagagtcc agagcttgac 500

 tgtgaggaag ggtggacacg gttaaagtgt ggaggaaacc aaaatgaaag 550

 agcgaaggtg tgctttgaga aggctctgga aaagaagcca aagaacccag 600

 aattcacctc tggactggca atagcaagct accgtctgga caactggcca 650

 ccatctcaga acgccattga ccctctgagg caagccattc ggctgaatcc 700

 tgacaaccag taccttaaag tcctcctggc tctgaagctt cataagatgc 750

 gtgaagaagg tgaagaggaa ggtgaaggag agaagttagt tgaagaagcc 800

 ttggagaaag ccccaggtgt aacagatgta cttcgcagtg cagccaagtt 850

 ttatcgaaga aaagatgagc cagacaaagc gattgaactg cttaaaaagg 900

 ctttagaata cataccaaac aatgcctacc tgcattgcca aattgggtgc 950

 tgctataggg caaaagtctt ccaagtaatg aatctaagag agaatggaat 1000

 gtatgggaaa agaaagttac tggaactaat aggacacgct gtggctcatc 1050

 tgaagaaagc tgatgaggcc aatgataatc tcttccgtgt ctgttccatt 1100

 cttgccagcc tccatgctct agcagatcag tatgaagaag cagagtatta 1150

 cttccaaaag gaattcagta aagagcttac tcctgtagcg aaacaactgc 1200

 tccatctgcg gtatggcaac tttcagctgt accaaatgaa gtgtgaagac 1250

 aaggccatcc accactttat agagggtgta aaaataaacc agaaatcaag 1300

 ggagaaagaa aagatgaaag acaaactgca aaaaattgcc aaaatgcgac 1350

 tttctaaaaa tggagcagat tctgaggctt tgcatgtctt ggcattcctt 1400

 caggagctga atgaaaaaat gcaacaagca gatgaagact ctgagagggg 1450

 tttggagtct ggaagcctca tcccttcagc atcaagctgg aatggggaat 1500

 ggagaataga gatgtggtgc ccactaggct actgctgata gggagctgaa 1550

 attcctccac caagttggta ttcaaaatat gtaatgactg gtatggcaaa 1600

 agattggact aagacactgg ccataccact ggacagggtt atgttaacac 1650

 ctgaattgct gggtcttgag agagcccaag gagttctggg agagggacca 1700

 gattgggggg taggtccacg ggcttggtga tagaattatt tctcgattga 1750

 cttcttgagt gcaatttgaa ctgtaacatt tgcttagtca cctttagtgg 1800

 agtaatccac tgggcttgtt tctatattta tataaagcag ccaaatcctt 1850

 catgtaatat tgaagtccat ttttgcaatg ttgttccata cttggagtca 1900

 ttttgcatcc catagaggtt agtcctgcat agccagtaat gtgctaagtt 1950

 catccaaaag ctgggggacc aaagtctaaa tagggctcag tatcccccat 2000

 cgcttatctc tgcctccttc ctcctccttc ccagtctatc atcaaccttg 2050

 agtattctac acaatgtgaa ttcaagtgcc tgattaattg aggtggcaac 2100

 atagtttgag acgagggcag agaacaggaa gatacatagc tagaagcgac 2150

 gggtacaaaa agcaatgtgt acaagaagac tttcagcaag tatacagaga 2200

 gttcacctct actctgccct cctcatagtc ataatgtagc aagtaaagaa 2250

 tgagaatgga ttctgtacaa tacactagaa accaacataa tgtatttctt 2300

 taaaacctgt gtgaaaaaat aaatgttcca ccagtaggga taggggaaaa 2350

 gtaaccaaaa gagagaaaga gaaaggaatg ctggtttatc tttgtagatt 2400

 gtaatcgaat ggagaaattt gcagtatttt agccactatt aggaattttt 2450

 tttttttgta aaatgaagac tgaactctgt tcaaatgctt tcatgaacct 2500

 ggtttgagac ggtaggaaag caacaaaacg tgggaacctg gtgactaagg 2550

 gcctggtgca aggacttggg aaatgtcatt aataatagat ggtggggttt 2600

 tccccccttt agaaatgttg gatattaagt gatataaaca cttcttttaa 2650

 ctccgaaaat cttctgagaa atcacaaaat tcacggtatg cttggaacga 2700

 ttgagatttt ctaggtagat gctgaatagc ctagacatca aagttggtgt 2750

 gaaccaaaat agagtcagct gacccagcat cagccacact ctgggttgga 2800

 aaatgtttgc ctgttggaat taatttaagc ttaagtatat atcaacatta 2850

 ttttattgtg caattaaaac aatacaaatt catggttttt taaagttaaa 2900

 aattctaacc actgtaacaa cagtttttgt gttattttct gtattaaaca 2950

 tcttgttgca cgcatttgag gtcatcaggg tgcaaaattt gtattcctga 3000

 aaatgtcata tattttcatt aataaataac ctaaatatga taaaacataa 3050

 aaaaaaaaaa aaa 3063

<210> 4416
<211> 460
<212> PRT
<213> Homo sapien

<400> 4416
 Met Glu Gly Glu Asn Ser Leu Asp Asp Phe Glu Asp Lys Val Phe
   1               5                  10                  15

 Tyr Arg Thr Glu Phe Gln Asn Arg Glu Phe Lys Ala Thr Met Cys
                  20                  25                  30

 Asn Leu Leu Ala Tyr Leu Lys His Leu Lys Gly Gln Asn Glu Ala
                  35                  40                  45

 Ala Leu Glu Cys Leu Arg Lys Ala Glu Glu Leu Ile Gln Gln Glu
                  50                  55                  60

 His Ala Asp Gln Ala Glu Ile Arg Ser Leu Val Thr Trp Gly Asn
                  65                  70                  75

 Tyr Ala Trp Val Tyr Tyr His Met Gly Arg Leu Ser Asp Val Gln
                  80                  85                  90

 Ile Tyr Val Asp Lys Val Arg His Val Cys Glu Lys Phe Ser Ser
                  95                 100                 105

 Pro Tyr Arg Ile Glu Ser Pro Glu Leu Asp Cys Glu Glu Gly Trp
                 110                 115                 120

 Thr Arg Leu Lys Cys Gly Gly Asn Gln Asn Glu Arg Ala Lys Val
                 125                 130                 135

 Cys Phe Glu Lys Ala Leu Glu Lys Lys Pro Lys Asn Pro Glu Phe
                 140                 145                 150

 Thr Ser Gly Leu Ala Ile Ala Ser Tyr Arg Leu Asp Asn Trp Pro
                 155                 160                 165

 Pro Ser Gln Asn Ala Ile Asp Pro Leu Arg Gln Ala Ile Arg Leu
                 170                 175                 180

 Asn Pro Asp Asn Gln Tyr Leu Lys Val Leu Leu Ala Leu Lys Leu
                 185                 190                 195

 His Lys Met Arg Glu Glu Gly Glu Glu Glu Gly Glu Gly Glu Lys
                 200                 205                 210

 Leu Val Glu Glu Ala Leu Glu Lys Ala Pro Gly Val Thr Asp Val
                 215                 220                 225

 Leu Arg Ser Ala Ala Lys Phe Tyr Arg Arg Lys Asp Glu Pro Asp
                 230                 235                 240

 Lys Ala Ile Glu Leu Leu Lys Lys Ala Leu Glu Tyr Ile Pro Asn
                 245                 250                 255

 Asn Ala Tyr Leu His Cys Gln Ile Gly Cys Cys Tyr Arg Ala Lys
                 260                 265                 270

 Val Phe Gln Val Met Asn Leu Arg Glu Asn Gly Met Tyr Gly Lys
                 275                 280                 285

 Arg Lys Leu Leu Glu Leu Ile Gly His Ala Val Ala His Leu Lys
                 290                 295                 300

 Lys Ala Asp Glu Ala Asn Asp Asn Leu Phe Arg Val Cys Ser Ile
                 305                 310                 315

 Leu Ala Ser Leu His Ala Leu Ala Asp Gln Tyr Glu Glu Ala Glu
                 320                 325                 330

 Tyr Tyr Phe Gln Lys Glu Phe Ser Lys Glu Leu Thr Pro Val Ala
                 335                 340                 345

 Lys Gln Leu Leu His Leu Arg Tyr Gly Asn Phe Gln Leu Tyr Gln
                 350                 355                 360

 Met Lys Cys Glu Asp Lys Ala Ile His His Phe Ile Glu Gly Val
                 365                 370                 375

 Lys Ile Asn Gln Lys Ser Arg Glu Lys Glu Lys Met Lys Asp Lys
                 380                 385                 390

 Leu Gln Lys Ile Ala Lys Met Arg Leu Ser Lys Asn Gly Ala Asp
                 395                 400                 405

 Ser Glu Ala Leu His Val Leu Ala Phe Leu Gln Glu Leu Asn Glu
                 410                 415                 420

 Lys Met Gln Gln Ala Asp Glu Asp Ser Glu Arg Gly Leu Glu Ser
                 425                 430                 435

 Gly Ser Leu Ile Pro Ser Ala Ser Ser Trp Asn Gly Glu Trp Arg
                 440                 445                 450

 Ile Glu Met Trp Cys Pro Leu Gly Tyr Cys
                 455                 460

<210> 4417
<211> 3204
<212> DNA
<213> Homo sapien

<400> 4417
 cttcagagac cctttggagg cacaatctgt ggttatcaca gccaggaccg 50

 gtacgaattc tcttcccaca ttgtccgggg ggagcataag gtgggctagc 100

 aacctctccc tctctcctca gtccaccact ccactgccct gactacaggc 150

 attgatccct gtccccacca tttcccaagg agttttgctt tgtagccctc 200

 actactggcc acctgacctc acacctgacc ctgacccctc ctcacctatt 250

 ctcttcctct atcctgaccg atgtaagcat tgtgatgaaa cagatctttt 300

 gcttatgttt ttccttttta tcttctctca tcccagcata ctgagttatt 350

 tattaattag ttgatttatt tttgcctttt taaattttaa cttatatcag 400

 tcacttgcca ctcccccacc ctcctgtcca caactccttt ccactttagg 450

 ccaatttttc tctcttagat cttccagcag ccccaggggt aggaagctcc 500

 tcttagtact aagagacttc aagcttcttg ctttaagtcc tcacccttta 550

 cattatctaa ttcttcagtt ttgatgctga tacctgcccc cggccctacc 600

 ttagctctgt ggcattatat ctcctctctg ggactcttca acctggtact 650

 ccatacctct tgtgccctct cactttaggc agcttgcact attcttgaat 700

 gaatgaagaa ttatttcctc atttggaagt aggagggact gaagaaattc 750

 tccccaggca ctgtgggact gagagtccta ttcccctagt aataggtcat 800

 attcccctag taatatgagt tctcaaagcc tacattcagg atctccctct 850

 aggatgtgat agatctggtc cctctccttg aactacccct ccacacgctc 900

 tagtcccttc aacctaccgg tctattaagt ggtggctttt ctctccttgg 950

 agtgccccaa ttttatattc tcaggggcca aggctaggtc tgcaaccctc 1000

 tgtctctgac agattgggag ccacaggtgc ctaattggga accagggcat 1050

 gggaaaggag tgggtcaaaa ttcttctctt tctcctccac ctctcaaact 1100

 tcttcactat agtgaccttc ctaggctctc aggggctcct tcagtcccca 1150

 tcctatgaga aactagtggg ttgctgcctg atgacaaggg gttgtttcag 1200

 cccctcagtc atgctgcctt ctgctgctcc ctcccagcag gattcaccct 1250

 ctcattcccg ggctcctggg ccctgttctt aggatcagtg gcagggagaa 1300

 acgggtatct cttttctctc ttctaatttt cagtataacc aaaaattatc 1350

 ccagcatgag cacgggcacg tgcccttcac cccattccac ccttgttcca 1400

 gcaagactgg gatgggtaca actgaactgg ggtcttcctt tactaccccc 1450

 ttctacactc agctcccaga cacagggtag gaggggggac tgctggctac 1500

 tgcagagacc cttggctatt tgagtaacct aggattagtg agaaggggca 1550

 gaaggagata caactccact gcaagtggag gtttctttct acaagagttt 1600

 tctgcccaag gccacagcca tcccactctc tgcttccttg agattcaaac 1650

 caaaggctgt ttttctatgt ttaaagaaaa aaaaaagtaa aaaccaaaca 1700

 caacacctca caagttgtaa ctcttggtcc ttctctctct ccttttctct 1750

 tcccttcctt ccccttccat ctttctttcc acatgtcctt tccttattgg 1800

 ctcttttacc tcctactttt ctcactccct atcagggata ttttgggggg 1850

 ggatggtaaa gggtgggcta aggaacagac cctgggatta gggccttaag 1900

 ggctctgaga ggagtctacc ttgccttctt atgggaaggg agaccctaaa 1950

 aaactttctc ctctttgtcc tcctttttct cccccactct gaggtttccc 2000

 caagagaacc agattggcag ggagaagcat tgtggggcaa ttgttcctcc 2050

 ttgacaatgt agcaataaat agatgctgcc aagggcagaa aatggggagg 2100

 ttagctcaga gcagagtagt ctctagagaa aggaagaatc ctcaacggca 2150

 ccctggggtg ctagctcctt tttagaatgt cagcagagct gagattaata 2200

 tctgggcttt tcctgaacta ttctggttat tgagcccttc ctgttagacc 2250

 taccgcctcc cacctcttct gtgtctgctg tgtatttggt gacacttcat 2300

 aaggactagt cccttctggg gtatcagagc cttagggtgc ccccatcccc 2350

 ttccccagtc aactgtggca cctgtaacct cccggaacat gaaggactat 2400

 gctctgaggc tatactctgt gcccatgaga gcagagactg gaagggcaag 2450

 accaggtgct aaggagggga gagggggcat cctgtctctc tccagaccat 2500

 cactgcactt taaccagggt cttaggtaca aaatcctact tttcagagcc 2550

 ttccagctct ggaacctcaa acatcctcat gctctctccc agctcctttt 2600

 gcataaaaaa aaaagtaaag aaaaagaaaa aaaaatacac acacactgaa 2650

 acccacatgg agaaaagagg tgtttccttt tatattgcta ttcaaaatca 2700

 ataccaccaa caaaatattt ctaagtagac acttttccag acctttgttt 2750

 ttttgtgtca gtgtccaagc tgcagatagg attttgtaat acttctggca 2800

 gcttctttcc ttgtgtacat aatatatata tatacactat atatatatat 2850

 ttttaatcag aagttatgaa gaacaaaaag aaaaaataaa cacagaagca 2900

 agtgcaatac cacctctctt ctccctctct cctagggttt cctttgtagc 2950

 ctatgtttgg tgtctctttt gacctttacc ccttcacctc ctcctctctt 3000

 cttctgattc ccctcccccc cttttttaaa gagtttttct cctttctcaa 3050

 ggggagttaa actagctttt gagacttatt gcaaagcatt ttgtatatgt 3100

 aatatattgt aagtaaatat ttgtgtaacg gagatatact actgtaagtt 3150

 ttgtactgta ctggctgaaa gtctgttata aataaacatg agtaatttaa 3200

 cacc 3204

<210> 4418
<211> 86
<212> PRT
<213> Homo sapien

<400> 4418
 Met Lys Asp Tyr Ala Leu Arg Leu Tyr Ser Val Pro Met Arg Ala
   1               5                  10                  15

 Glu Thr Gly Arg Ala Arg Pro Gly Ala Lys Glu Gly Arg Gly Gly
                  20                  25                  30

 Ile Leu Ser Leu Ser Arg Pro Ser Leu His Phe Asn Gln Gly Leu
                  35                  40                  45

 Arg Tyr Lys Ile Leu Leu Phe Arg Ala Phe Gln Leu Trp Asn Leu
                  50                  55                  60

 Lys His Pro His Ala Leu Ser Gln Leu Leu Leu His Lys Lys Lys
                  65                  70                  75

 Ser Lys Glu Lys Glu Lys Lys Ile His Thr His
                  80                  85

<210> 4419
<211> 4446
<212> DNA
<213> Homo sapien

<400> 4419
 gcttggttcc tgagcggatg ctggggctgt aaggcgcgcg cggtcagctg 50

 ttggcggtgc agggaggagg acgccggggc tcgccttccc tcctctgccg 100

 ccgctgccgc catgattccg gtgtcgctgg tggtggtggt aggtgggtgg 150

 ctggactgtc gtctacctga ccgacttggt gctgaagtca tctgtctatt 200

 ttaaacattc ttatgaagac tggctggaaa acaacggact gagcatctcc 250

 cctttccaca taagatggca aactgctgtt ttcaatcgtg ccttttacag 300

 ttggggacgg cggaaagcaa ggatgcttta ccagtggttc aattttggaa 350

 tggtgtttgg cgtaattgcc atgtttagct cattttttct ccttggaaaa 400

 acgctgatgc agactttggc acaaatgatg gctgactctc cctcttctta 450

 ttcttcctcc tcttcttcct cttcctcctc ttcttcctct tcctcttctt 500

 catcttcttc ctcttcctcg cttcacaatg aacaggtgtt acaagttgtg 550

 gttcctggta taaatttacc cgtcaatcaa ctgacctatt tcttcacggc 600

 agttctcatt agtggtgttg tacatgaaat tggacatggg atagcagcta 650

 ttagggaaca agttcgattt aatggctttg ggatttttct cttcattatt 700

 tatcctggag catttgttga tctgttcacc actcatttgc aacttatatc 750

 gccagtccag cagctaagga tattttgtgc aggtatctgg cataattttg 800

 tccttgcact cttgggtatt ttagctcttg ttctcctccc agtaattctc 850

 ttgccatttt actacactgg agttggggtg ctcatcactg aagttgctga 900

 ggactctcct gccattggac ccagaggcct ttttgtggga gaccttgtca 950

 cccatctaca ggattgtcct gttactaatg tgcaagattg gaatgaatgt 1000

 ttagatacca tcgcctatga gccccaaatt ggttactgta taagtgcatc 1050

 aactttacag cagttaagtt tcccagttag agcatacaaa cgactagatg 1100

 gttcaactga atgctgtaac aatcacagcc tcacagatgt gtgcttttcc 1150

 tacagaaata attttaataa gcgtttgcat acatgtcttc ctgcccggaa 1200

 agcagttgaa gcaactcaag tttgcagaac caataaagac tgtaaaaaaa 1250

 gctcaagttc aagtttctgt ataatacctt ctttggaaac tcacactcgc 1300

 ttaataaaag taaaacaccc acctcagatt gatatgttat acgtaggaca 1350

 tcctctgcat cttcactaca cagtgagcat caccagtttt atcccacgtt 1400

 ttaactttct aagcatagat ctgccagtgg ttgtggagac atttgtcaag 1450

 tacctgattt ccctctcagg agctctggct attgttaatg cagtaccctg 1500

 ctttgctttg gatggacaat ggattctaaa ctctttcttg gatgccaccc 1550

 ttacctcagt gattggagac aatgatgtca aagatctaat agggtttttc 1600

 atcttgctgg gtggcagtgt acttttggct gccaatgtga ccctgggact 1650

 ctggatggtt acagcacggt aatgtttgca ctcatctgac agaatccctg 1700

 agttacagta tacagctatg tggtaatatt cattgccatt gaaattctta 1750

 cttggtatga aatataaagt gtttccttaa aattacatct tagccaacaa 1800

 ccctgagctc ctcccatatc cagagtaccc aaactctgtg gtagaagata 1850

 agcagaagaa atgaaaggca tagtccctga ctatattcta atttaggact 1900

 gaatgtaccc agatgcttgt ggaataatat ctaagcaagt gcaaattcat 1950

 gtaataccgt tttgtctgat tacatattgt gttgaaatag tataaaggag 2000

 aacagaactg ggtggaatta attgggaaaa acttcttaca aaagcatcat 2050

 taatcaaaat ttgaaggaga ccagactttg gccaagtgga aggatgacca 2100

 ttgtcttggc ctgtatctct tgtcctttgt cttgtttgaa aagtatttta 2150

 aaacttaatg gtgtattatt ttgtgctctg aaagctgagg tctgattaca 2200

 attagtaaaa ttctatagaa gaatctgctg acgtgaaagg gaaaaatctt 2250

 tgtcaaatga taccaaataa atgaacaaaa caggaagtag ggcctatgat 2300

 atcgtgagac atgttttgcc ccacaagagt tgcatctttt ataaggtgtc 2350

 tctgccccct cataaagcag cactagcttt gacatccacg gtgagctgca 2400

 ggaagcatca cacaccagca gcatgtgagc agagggaggc agttggggtt 2450

 gaacttcgga actaggccgg gtctcctgac agatcacaag acaccccaga 2500

 ggatcttcag cagtcctact tcccattctc tatagagctt tgaagcttgg 2550

 aacccttcca gggtaaacat tttctcttgt gctgctcagg acatctgggg 2600

 cctagctcct gggttcctgt ctccaagaag caatgacctt aaactctgag 2650

 ccatactctg tcctcaccag cggctcccat gtttttctgt gtcaggttat 2700

 taagtaccta gtccttgttt tctgtctctc tcctaagcta cctctctggg 2750

 tccacagaag acttggtagt atagtgagaa tggctatacg tgagtacaaa 2800

 catggatttt ccagggcttg ggaactgatt cttgagccca gaagagccac 2850

 gcctgctttg aggtcttttg gagtggagat gcagccctgg gaaatttggg 2900

 gagtcagcag gccagtgtga agctattggt cctaggagta tatgagcttg 2950

 ctgtttcttt gatggaaaat acatgcttct cttgtatact cagaagtgac 3000

 taagggcaat aactcattaa tagccatcta tccaacttct ttactgagtg 3050

 atgtattcca tggggttacc tttttcagat tattgagttg ctctgtaagc 3100

 actaaaactt tttaatcatt tttaagaaac tttttagatt gtattacaaa 3150

 tttgccttaa cagtaattag atgttgaata taattttaac attttattaa 3200

 tgacttgggt catcagttaa taccagtact aaaaccatac gaattattgg 3250

 tttattccag aaaatacagt atttgttcta tttttaggta gacaatcatt 3300

 tgggatcaga gtacattagc atagtaatgc tcagtcagac ctgttcaagt 3350

 agtagagctt ggagaatgcc atgaaatact tatataatta atttgattgc 3400

 atgaactaag caattttact aatgaaaagg ttgtatatgt gcaagtcact 3450

 tttttaaaaa ccaagaaaaa actttaatag aggaaatctt attcattaat 3500

 ttatttttct gagtaaaaaa acgaaaccca aatctcattt tatttcaact 3550

 gttaaacatt ttgatctgtt gacccatagg atcaggattt gggaaccact 3600

 ttactaggaa agagcagatc agtaccattt gtataaaacc ggcctcatta 3650

 tgtaagaaag aaaatgttac gtgttttctt ctttagcttg gttgtgggca 3700

 cttctacagc aaggaccata tcatattcat ctttgcatcc ctggcacagt 3750

 gcatgagaca taagtactta ataaatgcag ttgaatggat aatgattagt 3800

 gttatttatg gattagaaaa agcatgtttc tatttaagta agctgtaaaa 3850

 agtattattg aatatttact gtaaatatat gttcacataa aaaaataact 3900

 tggagggtct ttgtgtccct ggcatattat catcttcatg gaaagaatcc 3950

 actgtggttt ctgtagagtg attggaaaaa tggattattt tgaggattga 4000

 agaaagtgtt ctttctgcgt tgtcactttg ttcaacagta aaactttatt 4050

 ctcagtgttc ctactctgca ttgtttacat ttttgacagt tttttttaat 4100

 cacctacaat ctgtaaagaa tgtatatatt cttttcagca tctcagtttg 4150

 aaaagacatg cagttaaact tgaccttttg ataatcgctc ttacaggtca 4200

 ttgtctgttc taacagcaaa ttgtaaacat gtgcttcata gatattgtgg 4250

 ctctcagtca tcactttgtc ctatggtatt tattgaatgt tcacatacta 4300

 atggtgcaca ggtgtttttt tctataaatc ttctgactgt cctgtaattc 4350

 attcttaagc tttaacttga aggtatcgta attgccggca tttgatgttt 4400

 agcaataaaa gaataaatgt gtaccagcat tttatgttta aaaaaa 4446

<210> 4420
<211> 556
<212> PRT
<213> Homo sapien

<400> 4420
 Ala Trp Phe Leu Ser Gly Cys Trp Gly Cys Lys Ala Arg Ala Val
   1               5                  10                  15

 Ser Cys Trp Arg Cys Arg Glu Glu Asp Ala Gly Ala Arg Leu Pro
                  20                  25                  30

 Ser Ser Ala Ala Ala Ala Ala Met Ile Pro Val Ser Leu Val Val
                  35                  40                  45

 Val Val Gly Gly Gly Trp Thr Val Val Tyr Leu Thr Asp Leu Val
                  50                  55                  60

 Leu Lys Ser Ser Val Tyr Phe Lys His Ser Tyr Glu Asp Trp Leu
                  65                  70                  75

 Glu Asn Asn Gly Leu Ser Ile Ser Pro Phe His Ile Arg Trp Gln
                  80                  85                  90

 Thr Ala Val Phe Asn Arg Ala Phe Tyr Ser Trp Gly Arg Arg Lys
                  95                 100                 105

 Ala Arg Met Leu Tyr Gln Trp Phe Asn Phe Gly Met Val Phe Gly
                 110                 115                 120

 Val Ile Ala Met Phe Ser Ser Phe Phe Leu Leu Gly Lys Thr Leu
                 125                 130                 135

 Met Gln Thr Leu Ala Gln Met Met Ala Asp Ser Pro Ser Ser Tyr
                 140                 145                 150

 Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser
                 155                 160                 165

 Ser Ser Ser Ser Ser Ser Ser Ser Leu His Asn Glu Gln Val Leu
                 170                 175                 180

 Gln Val Val Val Pro Gly Ile Asn Leu Pro Val Asn Gln Leu Thr
                 185                 190                 195

 Tyr Phe Phe Thr Ala Val Leu Ile Ser Gly Val Val His Glu Ile
                 200                 205                 210

 Gly His Gly Ile Ala Ala Ile Arg Glu Gln Val Arg Phe Asn Gly
                 215                 220                 225

 Phe Gly Ile Phe Leu Phe Ile Ile Tyr Pro Gly Ala Phe Val Asp
                 230                 235                 240

 Leu Phe Thr Thr His Leu Gln Leu Ile Ser Pro Val Gln Gln Leu
                 245                 250                 255

 Arg Ile Phe Cys Ala Gly Ile Trp His Asn Phe Val Leu Ala Leu
                 260                 265                 270

 Leu Gly Ile Leu Ala Leu Val Leu Leu Pro Val Ile Leu Leu Pro
                 275                 280                 285

 Phe Tyr Tyr Thr Gly Val Gly Val Leu Ile Thr Glu Val Ala Glu
                 290                 295                 300

 Asp Ser Pro Ala Ile Gly Pro Arg Gly Leu Phe Val Gly Asp Leu
                 305                 310                 315

 Val Thr His Leu Gln Asp Cys Pro Val Thr Asn Val Gln Asp Trp
                 320                 325                 330

 Asn Glu Cys Leu Asp Thr Ile Ala Tyr Glu Pro Gln Ile Gly Tyr
                 335                 340                 345

 Cys Ile Ser Ala Ser Thr Leu Gln Gln Leu Ser Phe Pro Val Arg
                 350                 355                 360

 Ala Tyr Lys Arg Leu Asp Gly Ser Thr Glu Cys Cys Asn Asn His
                 365                 370                 375

 Ser Leu Thr Asp Val Cys Phe Ser Tyr Arg Asn Asn Phe Asn Lys
                 380                 385                 390

 Arg Leu His Thr Cys Leu Pro Ala Arg Lys Ala Val Glu Ala Thr
                 395                 400                 405

 Gln Val Cys Arg Thr Asn Lys Asp Cys Lys Lys Ser Ser Ser Ser
                 410                 415                 420

 Ser Phe Cys Ile Ile Pro Ser Leu Glu Thr His Thr Arg Leu Ile
                 425                 430                 435

 Lys Val Lys His Pro Pro Gln Ile Asp Met Leu Tyr Val Gly His
                 440                 445                 450

 Pro Leu His Leu His Tyr Thr Val Ser Ile Thr Ser Phe Ile Pro
                 455                 460                 465

 Arg Phe Asn Phe Leu Ser Ile Asp Leu Pro Val Val Val Glu Thr
                 470                 475                 480

 Phe Val Lys Tyr Leu Ile Ser Leu Ser Gly Ala Leu Ala Ile Val
                 485                 490                 495

 Asn Ala Val Pro Cys Phe Ala Leu Asp Gly Gln Trp Ile Leu Asn
                 500                 505                 510

 Ser Phe Leu Asp Ala Thr Leu Thr Ser Val Ile Gly Asp Asn Asp
                 515                 520                 525

 Val Lys Asp Leu Ile Gly Phe Phe Ile Leu Leu Gly Gly Ser Val
                 530                 535                 540

 Leu Leu Ala Ala Asn Val Thr Leu Gly Leu Trp Met Val Thr Ala
                 545                 550                 555

 Arg


<210> 4421
<211> 6055
<212> DNA
<213> Homo sapien

<400> 4421
 ggaattctgt ctggagtcat atcttcaacc attgctaatc caactgatgt 50

 tttgaaaatt cggatgcaag cgcaaagcaa caccattcaa ggaggaatga 100

 taggcaactt catgaacatt taccagcaag aggggacaag aggactgtgg 150

 aagggtgtgt cccttactgc gcagagggct gctattgttg ttggtgtgga 200

 gctgccggtc tatgacatca ccaagaagca tcttattctc tcgggcctga 250

 tgggagacac tgtgtatacc cacttcctct caagcttcac ctgtggtctg 300

 gcaggggccc tggcctcaaa ccctgttgat gttgtgagga cacgtatgat 350

 gaatcagaga gtgcttcgag atggcagatg ttctggctac acaggaaccc 400

 tggattgctt gttacaggta agagcagatg tctgtctctg cagggttgtg 450

 aattatatat ttttttgatc taagaagtaa ctaaattatg aaagctacta 500

 aaactaagat gaatgatgct ttaaagccca gagatgtaca tgtgtgagac 550

 catttttgcc acactgtgct tagcttttat aaatacaatg ttgttttctt 600

 tatacctcca tctgctgtga aaggtgagga aatatttcct gtgattataa 650

 aagaactggg tctccttcca aaatgtactt tcttcctgtt gggtcaaact 700

 agtatgaata tccctcattc agacatctct gttaaaggaa cacatcaatc 750

 ttactttaat tctcagttta aataattggg cctcctgttt tatgagtggg 800

 tgaaaggttt cacctgtctc tgccactaga ttgccagtag taggattagg 850

 agtcactttt tttttttttt ttaaggtgat atttatttat ttattttcaa 900

 gttttaatgt attttagatt cagggggtac atgtgcaggt gtgttacata 950

 ggcacatgcg tagtggtgga gattgggctt ctaatgtacc cattacccaa 1000

 atagtgagca ttacaccaga cagataattt ttcaactcta gcctctcccc 1050

 tttaggagtc cccagtgtct gttacttcta tctttatgtc cgtgtgtacc 1100

 cattgtttag ctcccactta aaaatgagaa catgtggttt ttgatcttct 1150

 gtttctgcgt tagtttgctc aggataatgg cctccagctc catccatgtt 1200

 gctgcaaaga acgtgatttc ttttttatgg ctacaggggc cacttttgtg 1250

 gttcctgttt tccaacatga cactagcaca ttttattctt caggtgttgc 1300

 cttaatgaag caaagacact tatcgtattc atccacctga catcttggga 1350

 aatagtggta ctctgaatga tatctctacc actattgctt ctttatttgt 1400

 gacctgttca ggagcccaca tggcacggaa gcaacagacc gtaattggaa 1450

 ttaaatctaa ttttttcctc actcaacagt gtttatctcc tttgtgtgga 1500

 gttcattcaa tccttcgtgt ggggttgttg ggcatggagc cttagtcttc 1550

 cacccacaca agcctctaaa gagcaaagat ttcttaggca gtccttccaa 1600

 acaggatttt atttttaaga aaaataaatc agtctggcca ctaattatta 1650

 ttattatttt ttgagatgga gtctcgcttt gtcgcccagg ctggagtgca 1700

 gtggcgtgat cttggctcac tgcaagctcc gcctcccggg ttcatgccat 1750

 tctcctgcct tagcctcccg agtagctggg actacaggcg cctgccacca 1800

 tgcccggcta attttttttt tgtattttta gtagagacag ggtttcactg 1850

 cattagccag gatggtcttg atctcctgac ctggtgatcc acccgcctcg 1900

 gcctcccaaa gtgctgggat taaaggcgtg agccaccgcg cctggcctgg 1950

 ccactaatta ttaatgcatt tggcataatt agaaagttgg aagttaactt 2000

 ttttttcttc ttttaacaga catggaagaa tgaagggttt tttgctctct 2050

 ataaaggctt ttggccaaat tggttgagac ttggtccttg gaatatcatt 2100

 gtatcctttt ctgttgcaat agatctgaaa aaagatacag ctaaagaata 2150

 ctatttgtat aaactctcat gttattaatt ataatttaga agtaggttct 2200

 gattattttg agttcctctg atgctaagaa gtcactactt agtttctttt 2250

 ttaggaagtg taaagtctcc gtgctagaca ctgaatcttg ctttgatggt 2300

 ggtattattc aaaagtagtg atactactaa aaaggtttag ttagactctg 2350

 ttctagaagc tgagggtatt tacgatttca gagagagaga gaggaggatt 2400

 ggctttatag ccctagccac cttgggaagg atgtggttgg caacagtgtc 2450

 ttagaatgct tatcttagaa agtgcctgaa gataaacagg aattagctcc 2500

 ggaattgttt ggcaggccag cacgcttcct atgtgccaca gtgggaggca 2550

 ggaaaggaaa ggcagttaac ttttttttgt ttttgagact gagtctttac 2600

 tctgtcgccc aggctggagt acagtggcgt gatctcgggt cactgccacc 2650

 tccgcctcct gggttctagc aattctcttg ccttggcctc ctgagtagtt 2700

 gggattacag gcacataaaa ccacgcctgg ctaatttttg tgtttttagt 2750

 agagatgggg tttcaccatg tcagccaggc tggtctcaaa ctcctgacct 2800

 caagtgacct gccccttggc ctcccaaagt gctgggatta caggcgtgag 2850

 ccaccgcgcc cgtgaggcag ttaattagac actgaagggc agagtgatga 2900

 agcaggaatg ctggcttttg ctgtcctctt gttgctcttc atcagctcct 2950

 gcctcccaag gaaggatgca tagtggaagc ctttgaggag agcttcccag 3000

 ggcttgctaa ctctctctct ctctctctct ctctcaaaag cttacagtgc 3050

 tggaaagttt ttccaccaca gcaaagccac aaaagcttat cagcgtagat 3100

 gccatctcag aagaggctga taccagggga tttacatatc tcagctgtga 3150

 tctttctgct ccaagctgac cttggaagat agtttgatgt ggttaagggt 3200

 ggaacccctt ttatttaatc gtgtccatag cgtgggtctg cctgtaccta 3250

 tttgttatta agtgtgccat ttgtaagtct gttgttatgc actggagttg 3300

 tgaagatggc attttctgtg tcatccttaa cccataacca cagttctttg 3350

 tgacatacga gcagttgaag aaattggatt tgtgacaagc caaggctgca 3400

 tgagacatct ttctgaaaat ggtaacttct gaaacagcaa agcttcctgt 3450

 gtttcactct gcttctcact gcttggctca tcacagattc tgggatgtga 3500

 gcaacagatg aagactgggt tagttgagat tgctgtgtgt tggcattgga 3550

 tgctcttcat caaacgttta atggcataaa ctaacatcca aacactagtc 3600

 tttaccactg aagtgccctt caacatcaaa gataatatgt gaaatgcatg 3650

 tttcttgcta aagaaaactt gcaagaaaat caggagcgat gtattgtttt 3700

 attcagggag agtagctcct gatgcatctc agctcatgac tgagaatcag 3750

 actgctctag aaaagctcac tggaaccatg gaatggagcc tccgagaagg 3800

 tgttatggtt tctgaatttc tgggagattt tgctccttgt caactgaaga 3850

 aatttcatgt atggagacct ggactgttca accccaggta taaacggtgc 3900

 aggaaatgga tcctaggaat atcacactgc tttatcattt cctattttgg 3950

 caggatcttc cacttataat aagtgatttt aagctttgaa gacttgacat 4000

 ttgtgagaaa ttgttacaaa gtaataatct ctaaattcgt ggtggtgtta 4050

 tgtgttggct ttgaaggttg caaggtctgt attggtgggg ggtgttttca 4100

 agcagcttag gttctgtctt aggtcatgtt agtaattagc tttatgattt 4150

 ttagcaaagc atatgtattt ctcaatgagt aaaatgggga taataacgtc 4200

 tattgatgta gagggtcaaa tgaagaacaa atagtagctg ctgctacttg 4250

 actggaaagg taaatgtgtt tacatcatgc tgtggaacag ctctaaacag 4300

 tctatgtaga agaggggcat gttctcatgg gcttctcatg gtaattgtga 4350

 atgaagccct ttgttaaggt cttgttgaag aaagaacact gtataagttc 4400

 aggctttagt acattttcct tagcaaaatg ttggtagtga atcaaagagt 4450

 tgatttttcc aggtttccag tttttacttt agtttatgtt gtgcctgtct 4500

 tggactttct gtttagtttg gatggaaaat acctgcttga aattttaaaa 4550

 atgatttctt tagtgcatct atttagctag tttctgatag gtggtatgta 4600

 atattttccc tttttctttc cttctgtaga cacaataagt cattctccct 4650

 cttctttttt tctttttcta ttttcttatt ctttactcta acctgcttca 4700

 gagaaagagc cctcttcctt cttgtcttca tcttagtctt ttcaaaataa 4750

 aagatgactg tgagaacccc aagaacttcc acttctggga ggcagccaca 4800

 ggacagggaa catatttatt tgggtctctt cagttccccc tttgagaaca 4850

 acattaaata catgttagct ggggctccag ggcattctcc ttccacagta 4900

 gtgcggccaa attcccagtc tggccagtct ctttgttgag actgaataga 4950

 aggactgcag gtttttttgg aggatgagat aatttttcct cgcaggcatt 5000

 tttcccttgc cttccttatg catgaatggt ccctttgaat attatttcca 5050

 aaagtgagag ctaagacaaa gtcatcaaaa agagaggata acagaaggtg 5100

 ggggcggggg cggggtgcag tggggtaggg ttacctgtta attgctgaga 5150

 ctcagatgaa agtccagctc tccctgggca accctagagg gcagcagagg 5200

 accccagagc tcattcaggc cttgctgctt gttctaaact acaccttagg 5250

 attttttctt ctttccaaag cattccattg attttataaa gactttctat 5300

 agagaggctt tcacttttga gttctttgag tttaaagatt gcttttcttg 5350

 aaatgctctt tttttaatgt agaaaaattt tactttttca aatatgcata 5400

 caatttttaa aacagtagaa gcaaattcat tttaatgacc atgtaaagag 5450

 cgaatgtcag acagtattat taccagttta ttcaaattac atacatgttc 5500

 ctaccaaggt ggaaagaaat tcaaacctca tggtaaaact taagcacgat 5550

 ttaagataaa agcatagtat ttcttcagtg tagacttatt aagtgcctta 5600

 ttgaacagga tcttaacctg ctttttctgt ttttttgaaa gagttaatgc 5650

 aattgttgaa gcttctaacc aagaaacaac ttaaggaatt gggagacttg 5700

 gtcccctcgt tgtcagggtt ctggctataa gtacctcccc acctttgggt 5750

 tttcttaaat atgccaaaag gaattctagt ttttataacc aatgggtttt 5800

 tttgtttgtg tgcttatgga tttgtgtaat cattgatgct taatgttgtg 5850

 gattcataat ataaaaagtg gctcctgtcc tttatattta ttcatgtgct 5900

 agaaatagta tgcattatat aaagagtatg aagttttcat aagcctttat 5950

 atttcaagct ctttatttaa acattgttgg aatatgtggc ataagccttg 6000

 tttcatttat ttaataaact ggagtaatat ataataaaaa aaaaaaaaaa 6050

 aaaaa 6055

<210> 4422
<211> 155
<212> PRT
<213> Homo sapien

<400> 4422
 Gly Ile Leu Ser Gly Val Ile Ser Ser Thr Ile Ala Asn Pro Thr
   1               5                  10                  15

 Asp Val Leu Lys Ile Arg Met Gln Ala Gln Ser Asn Thr Ile Gln
                  20                  25                  30

 Gly Gly Met Ile Gly Asn Phe Met Asn Ile Tyr Gln Gln Glu Gly
                  35                  40                  45

 Thr Arg Gly Leu Trp Lys Gly Val Ser Leu Thr Ala Gln Arg Ala
                  50                  55                  60

 Ala Ile Val Val Gly Val Glu Leu Pro Val Tyr Asp Ile Thr Lys
                  65                  70                  75

 Lys His Leu Ile Leu Ser Gly Leu Met Gly Asp Thr Val Tyr Thr
                  80                  85                  90

 His Phe Leu Ser Ser Phe Thr Cys Gly Leu Ala Gly Ala Leu Ala
                  95                 100                 105

 Ser Asn Pro Val Asp Val Val Arg Thr Arg Met Met Asn Gln Arg
                 110                 115                 120

 Val Leu Arg Asp Gly Arg Cys Ser Gly Tyr Thr Gly Thr Leu Asp
                 125                 130                 135

 Cys Leu Leu Gln Val Arg Ala Asp Val Cys Leu Cys Arg Val Val
                 140                 145                 150

 Asn Tyr Ile Phe Phe
                 155

<210> 4423
<211> 4538
<212> DNA
<213> Homo sapien

<400> 4423
 atgtccgggg tccgggagga gaaaagtgtc tctcatctgt cccatcaaag 50

 caaattagtg aaacctgcct caggtgaagt gcaaaggcca gtctgtaggc 100

 agagtttcga cctctcccca cgagattggc tagacatcac ctgcccaagc 150

 tctctcccga cctgctagag ccgagagggc ggaggccgga gaggctgcag 200

 ccgggaagta gcaccgccac cgcacatccg ggaacgccag cagccggctg 250

 agggctgcat aactgatgga gggccgggcg cggtaagagc gtctcggggg 300

 agtggggcaa ggcggccggg cccctcccat gccgcctttt cttcagcgtc 350

 ctacccgcgg cactggctgc gagcgccggg ccacctgcga gtgtgcgcag 400

 ggactctgga cacccgcggc ggcgagctga gggagcagtc tccacgagga 450

 cccaggcgga ccctctggcg ccatgcgcgc ccttcccggc ctgctggagg 500

 ccagggcgcg tacgccccgg ctgctcctcc tccagtgcct tctcgctgcc 550

 gcgcgcccaa gctcggcgga cggcagtgcc ccagattcgc cttttacaag 600

 tccacctctc agagaagaaa taatggcaaa taacttttcc ttggagagtc 650

 ataacatatc actgactgaa cattctagta tgccagtaga aaaaaatatc 700

 actttagaaa ggccttctaa tgtaaatctc acatgccagt tcacaacatc 750

 tggggatttg aatgcagtaa atgtgacttg gaaaaaagat ggtgaacaac 800

 ttgagaataa ttatcttgtc agtgcaacag gaagcacctt gtatacccaa 850

 tacaggttca ccatcattaa tagcaaacaa atgggaagtt attcttgttt 900

 ctttcgagag gaaaaggaac aaaggggaac atttaatttc aaagtccctg 950

 aacttcatgg gaaaaacaag ccattgatct cttacgtagg ggattctact 1000

 gtcttgacat gtaaatgtca aaattgtttt cctttaaatt ggacctggta 1050

 cagtagtaat gggagtgtaa aggttcctgt tggtgttcaa atgaataaat 1100

 atgtgatcaa tggaacatat gctaacgaaa caaagctgaa gataacacaa 1150

 cttttggagg aagatgggga atcttactgg tgccgtgcac tattccaatt 1200

 aggcgagagt gaagaacaca ttgagcttgt ggtgctgagc tatttggtgc 1250

 ccctcaaacc atttcttgta atagtggctg aggtgattct tttagtggcc 1300

 accattctgc tttgtgaaaa gtacacacaa aagaaaaaga agcactcaga 1350

 tgaggggaaa gaatttgagc agattgaaca gctgaaatca gatgatagca 1400

 atggtataga aaataatgtc cccaggcata gaaaaaatga gtctctgggc 1450

 cagtgaatac aaaacatcat gtcgagaatc attggaagat atacagagtt 1500

 cgtatttcag ctttatttat ccttcctgtt aagagcctct gagtttttag 1550

 ttttaaaagg atgaaaagct tatgcaacat gctcagcagg agcttcatca 1600

 acgatatatg tcagatctaa aggtatattt tcattctgta attatgttac 1650

 ataaaagcaa tgtaaatcag aataaatatg ttagaccaga ataaaattaa 1700

 ttatattctg gtcttcaaag gacacacaga acagatatca gcagaatcac 1750

 ttaatacttc atagaacaaa aatcactcaa aacctgttta taaccaaaga 1800

 attcatgaaa aagaaagcct ttgccatttg tcttagaaag ttattttttt 1850

 taaaaaaatc atacttacta ttagtatcta tggaagtata tgtaacaatt 1900

 tttatgtaaa ggtcatcttt ctgtgatagt gaaaaaatat gtctttacta 1950

 agttgaaatg aatactttct gcctttgcta atgatagtta ttctacaatc 2000

 tccacaagaa aaatatacct tttatccgga aatattggtt taaggcaaat 2050

 aaataaaact gtgcttgctc taaagctctg cactacaaaa gcaaattttc 2100

 cagtctttat tccactcata accactgctt tccccaccag gctaaagtgc 2150

 ttcttagtct taaatagggt ttttaacttc ataaggtaca ccattgttta 2200

 tgttttaggg tgcaggtcca tatagtcgta atacttaaaa cactgctaca 2250

 ctgatgcttt tgtggctcat ggtttcctgg ttctttgatt taacacctgg 2300

 cttcctggta tctatggctg gttaaatatc taaacctgca ttattagtgc 2350

 tttacaataa taattccctt gactgaagtc cagaaatact aaagcacttc 2400

 ttttttattg ctgtgaatgc cttagactta tcttccaaaa taggatactt 2450

 cgtttctatt gcatatataa ctgaaatatt ttataaactc actgtaatca 2500

 aatcttataa aatctgaatc aacatgaaaa gttgtcaatg cttgaatgaa 2550

 tactaaaatc ataccacaag atactagata acataaatga ccatgaagtg 2600

 tcccactgct caaagggcaa caactttaag aacagaagca aagagtggtg 2650

 gtgtggaacc caagattctt ggcgactagg gaatttaaag gttggggagg 2700

 aggaattcaa tgatttgaca agaaatactt tataaaaatt tgctccatgt 2750

 attggctaag aaaaatataa taaaattttg gtagtgaaaa ttgtatcact 2800

 aatgtttacc aatattacta gtatgaataa tacacataag gtagtgactt 2850

 ggaagctgct caatactttg ttgctataac aaaatgcaat attttgttgt 2900

 aaagcatctt aactacacat ataagtttgc tgaacttgaa tacatcccgg 2950

 taatggcaaa cttcatttta ttcttggttt tcattttatt ctggtctcag 3000

 ggccatacat ttattttagt ttaattaatt attattttga caacattact 3050

 tgggtaatat ctatataatg gtagataacc aatcagttag cttaattaat 3100

 ctaagctatt tgaattcagg gaaatattag tcaaatctgc tgtttgacta 3150

 aatacaattc aaagcagtgt atttgtgact tggaatatag aacacaaaca 3200

 aatgtgtaac ccatctgcag tatgcattct tccattttac caccactaac 3250

 cattgaggct catacaattt tcaagcaaca agcattgctt cccaaaggta 3300

 aaataatcag gaatatttct atagtaaatg gagtttttaa ttggcaatac 3350

 tgtttatttt tttctagcaa agacaattta tctcagtaac cttaaatagg 3400

 aaaagtactc aaaaattaaa gttgactttt ggctttttgt agtctctctg 3450

 gaggacttcc agaaaattac cactgttgga ttttaatctg cttccattaa 3500

 ccaatcttac agagatgata aatgaattaa ctaatattga ccaaatataa 3550

 attgactgca aataataagc cgcataaaag ttgaagtagg aaaactactc 3600

 caagtttata tattaggcac cttggggaat tctcttagtc tttccagcta 3650

 acaaggattt tcagcataat aagtagattt aatgatggca taaaattccc 3700

 agatactttc atatacattt tttgccaaag tgtaaatctt ctccttttgc 3750

 agtctttttg ttattatccc aacatctagc tgctcaggcc ctaatttaga 3800

 actcattctg atattttctt cttctgtatt aattaatact tatgggtcat 3850

 gaatccctgc tcctttgacc tttttaatag ctcatgaatc catcccattg 3900

 cctccccaac tctgcccaca cctgctgcaa cagctaatgc cttgattttc 3950

 ctacctcagt ctccttttct attaatccct cttttgcgtg gctgcctgag 4000

 tccactttct caaacacaaa cctcactatg caactttgga atctctgtag 4050

 gctcaccttt gccatttctt aatattgcat tctccaaatt gctaatctct 4100

 atccagtctc ttgaactaga cttggcacat ggagattccg ctcagaaagt 4150

 gctcttcaca cttctacctg cttgactaac cccagattat ctttcaagac 4200

 tttaatctga tcttgtgtct tagagaagcc cccatacctg gtagagcatg 4250

 taccatctta catgcttaaa taactccaca tttatttgtg tttattactc 4300

 tgtgttataa atatacattt gttggtctct ctcttggatt attttgtttc 4350

 tttgtcctgt aactaccact gaaagggtgc aatacagctt tcttgaaatg 4400

 tgtattgaac ggatgaatgt ataaataaaa attaaatttt gtaaatttct 4450

 gcttattctt agaaaaagaa tctaaattgt gacaaatcag aattgaaaaa 4500

 agtattctaa taaagaaaaa caagctttta taacttca 4538

<210> 4424
<211> 327
<212> PRT
<213> Homo sapien

<400> 4424
 Met Arg Ala Leu Pro Gly Leu Leu Glu Ala Arg Ala Arg Thr Pro
   1               5                  10                  15

 Arg Leu Leu Leu Leu Gln Cys Leu Leu Ala Ala Ala Arg Pro Ser
                  20                  25                  30

 Ser Ala Asp Gly Ser Ala Pro Asp Ser Pro Phe Thr Ser Pro Pro
                  35                  40                  45

 Leu Arg Glu Glu Ile Met Ala Asn Asn Phe Ser Leu Glu Ser His
                  50                  55                  60

 Asn Ile Ser Leu Thr Glu His Ser Ser Met Pro Val Glu Lys Asn
                  65                  70                  75

 Ile Thr Leu Glu Arg Pro Ser Asn Val Asn Leu Thr Cys Gln Phe
                  80                  85                  90

 Thr Thr Ser Gly Asp Leu Asn Ala Val Asn Val Thr Trp Lys Lys
                  95                 100                 105

 Asp Gly Glu Gln Leu Glu Asn Asn Tyr Leu Val Ser Ala Thr Gly
                 110                 115                 120

 Ser Thr Leu Tyr Thr Gln Tyr Arg Phe Thr Ile Ile Asn Ser Lys
                 125                 130                 135

 Gln Met Gly Ser Tyr Ser Cys Phe Phe Arg Glu Glu Lys Glu Gln
                 140                 145                 150

 Arg Gly Thr Phe Asn Phe Lys Val Pro Glu Leu His Gly Lys Asn
                 155                 160                 165

 Lys Pro Leu Ile Ser Tyr Val Gly Asp Ser Thr Val Leu Thr Cys
                 170                 175                 180

 Lys Cys Gln Asn Cys Phe Pro Leu Asn Trp Thr Trp Tyr Ser Ser
                 185                 190                 195

 Asn Gly Ser Val Lys Val Pro Val Gly Val Gln Met Asn Lys Tyr
                 200                 205                 210

 Val Ile Asn Gly Thr Tyr Ala Asn Glu Thr Lys Leu Lys Ile Thr
                 215                 220                 225

 Gln Leu Leu Glu Glu Asp Gly Glu Ser Tyr Trp Cys Arg Ala Leu
                 230                 235                 240

 Phe Gln Leu Gly Glu Ser Glu Glu His Ile Glu Leu Val Val Leu
                 245                 250                 255

 Ser Tyr Leu Val Pro Leu Lys Pro Phe Leu Val Ile Val Ala Glu
                 260                 265                 270

 Val Ile Leu Leu Val Ala Thr Ile Leu Leu Cys Glu Lys Tyr Thr
                 275                 280                 285

 Gln Lys Lys Lys Lys His Ser Asp Glu Gly Lys Glu Phe Glu Gln
                 290                 295                 300

 Ile Glu Gln Leu Lys Ser Asp Asp Ser Asn Gly Ile Glu Asn Asn
                 305                 310                 315

 Val Pro Arg His Arg Lys Asn Glu Ser Leu Gly Gln
                 320                 325

<210> 4425
<211> 6309
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 267-571
<223> Unknown base

<400> 4425
 catgagccac catgtctggc tgattaattt tttttttaac tgtaagagtt 50

 tgatcttttc aaatgtgttc agaaactaat ttggattctt tgattctagt 100

 atctcaacgt gtttattttt agattctgat aagtgaaatg gatgtccttg 150

 tggagctctg gcctccccag cttatctatc agtcctgctg tcctcacctc 200

 cttgcctctt tccatgctta cccttaagcc accatctttc tcagctagcg 250

 tgtgtgtttc tagtgtnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn ntacacatta ggatgatcta tattgaaatc 600

 tacatggaac agagtgggac ttctaattgt atgacttcaa gattttgctt 650

 tgtttaaatt aataactgtt ttcagaatta agtgcttaaa aacaaatttg 700

 attgaaaagt tcaagacaag aattttgctc tctatggctg ttccatataa 750

 atttgatggt tgattctgaa tgtaaatgac tgaagaatta aaaaataaga 800

 aattcctttt taaaaggcat gcctcttgca ctgtgaacaa gacagtagtc 850

 ccttaaacca tgaatatgtc agtgttctat ggattacgaa attagtaatg 900

 ttgcttagcc caaacgtgtt ttttaaaaag tatagttttg tacatctcta 950

 agttatcaaa cttcaaaatt gagaacaaat ttaaaagtcc atatatgcaa 1000

 ctctagtaag cacttaatag gttacatagc actggttaag aacaattaat 1050

 tttgtttcta tattattact aattattatt acaaatcaaa aaacactgtg 1100

 ataagaactt caaagcatat atacaaatat agttaaagca atgaatagat 1150

 gaaacatgtc tactttattt catttagaaa ggaattaact tttttgttag 1200

 gcttttaaga aaagttctat tcattttaat cccctaggga atttgtaata 1250

 tgtcctactt catatcatct tctgttgcct ctattgatcc acattttctg 1300

 cagtggattt cttgaaaaga atcacactta tagtatgcct ctagaaatat 1350

 gattttactg ctttgaagtt tacatgaaac atgccagttg cttaactcta 1400

 attttttata tgaatctcag tagcactttt gttgtacatt gtgttccaat 1450

 aagtatagta tggaacactt tctcattttt agttcccata atatgccagt 1500

 ttttgctttc ctagtgttct gtgagtatta ggatttggca atctgctttt 1550

 gcatttcaat ttctgtttta catgcaagaa aaacatggac actcttacgt 1600

 ggtgcttgta gctgtgtctc cgtagagctc agtaaatagt tctacagggt 1650

 ttagaggatg agaagcgatt gtcaaattag gctgaattgt agaacacaaa 1700

 taatttaatt caaaataact taccaatttt atatacatga taaagtattc 1750

 agacaacttt ctaaatgcat aatagtaaaa gattgtgacc agatattatg 1800

 atattaataa agttaccaga tactaaaatc aatgaatgta atttgaatta 1850

 cttagaaatt gtatattaga gcccttatga gtaaaaacat ttcatttagc 1900

 aacttaactt ttagaatatt cttcctactt agggattttg attagattgt 1950

 aacattaaat tcgagaatat ttagtctcaa gagaaacact tcctggcatc 2000

 catcttaaat agtggccttt tcccactatg gtgtttttaa atgcatattc 2050

 atatataata gtatgtttct tacatttaat ccctaaataa cttagataat 2100

 cattcagtgg agaacaagta aaaggatatc attccttttg gagataaaca 2150

 ttgagtgtct agaatttttt tctattaatg ctttgtatat tagtttttta 2200

 aataagatct atagatatgt atttatgtgt gtcttatata tgaaacagtg 2250

 ctctgggttt gactcctatg ttttgtaatt ttaaaaacta cgatatgctt 2300

 gcagaaattc attgagaagc tgttataaaa aatgcagtga agcatgacca 2350

 aatagctaaa aatattactg aatctttaca aatatataat ctttattgtt 2400

 gtactgtgga gtgcaaggat actaaatatt ggctattgat aaaatactaa 2450

 cttgcatttc atggcaaata gatgttatat cgcttgatta gtctagaaca 2500

 tttctaatat tttgtgcttt catatatcaa aggagattat gtgaaactat 2550

 ttttaaatac tgtaaagtga catatagtta taagatatat ttctgtacag 2600

 tagagaaaga gtttataaca tgaagaatat tgtaccatta tacattttca 2650

 ttctcgatct cataagaaat tcaaaagaat aatgatagag gtgaaaatat 2700

 gtttactttc tctaaatcaa gcctagttgt caactcaaaa attatgttgc 2750

 atagttttat tttgaattta ggttttggga ctactttttt ccagcttcaa 2800

 tgagaaaata aaatctacaa ctcaggagtt actagagaag ttctaagtat 2850

 ttttttgcta agtagtaaaa atataaacat atgaaaatgc cataatgcct 2900

 gtcatagtca ttgtttcata ttttgtcata taaaatcacc taccctgctt 2950

 ctagttttat actttaatct gagtgaaagt atgatgtggt ggaaagaaaa 3000

 aacagtacag tattacatct gagttagtct ttgaaaaatc atagtagtaa 3050

 atgaacctca acactgagtg gtcaaaaatt gggttaacca atggggggag 3100

 aatatttggt taattgtttt aatattaaat tttcaagttt ataatagagt 3150

 tatggttgag tagtcatcca tactgagtaa tcacgcattt tttaaactat 3200

 aattgaggct cttctaaagc tttgttttct aatctaagat acaaaggata 3250

 ttcttgatct tgcttgattg taactacatc taccagtctt taatgtctgt 3300

 ttggggtgag tggcgatcct ctgttgtagg aatgtttttg aagatttcta 3350

 ttttgttttc cacttaggaa attcccctct ctcatttggg gtatatgcgt 3400

 tgagtataag gtaggctgta tttagacaca ctagaatcat taaatgtagg 3450

 tgaagttgta gagaaaaatg gcctgggtca atgtaggatc tagaaaatta 3500

 ggagtgtaca tttgctggct tctttttgag ttttgtactg tttattacag 3550

 gaacatattt gtgtggctaa tctctagggt gacagtgagt actaccctgc 3600

 tccttctgca ttctagttat ccaacacacc cagcagattg tgttcaggga 3650

 cagaatgtgt ttttagaaat cccttattat tgaaatgaat aataatatag 3700

 ctataaatat gaatgtctgg aggtatccag atgtgcctta acaaatgtaa 3750

 atggttttca ttcagaagtt tacattttta ttacattata aaatctcatc 3800

 attgggaact ttctaaacca tgaatatcag ttcttttaat gaaatttagg 3850

 tggtgcttta tcattttgga gaagttgctg tttgggacaa tagcatcagt 3900

 ttatcaagaa gtgtactcac catgatattc aacaatgtgt tacatttgac 3950

 aaaacgtgtt tagagtaaga aagactaact atactgtctg ttatatttat 4000

 ttatgctttt tgtagtttag ctacatacta taattttcat tttaaacgtt 4050

 ccttagttac tacaaataat atttatgttt tgcttcttct tagatgtagg 4100

 cggatgcaga aatagaatta tgttagagaa attattaaaa gtttaattcc 4150

 agtaggcagt tggagaaatc tgaaactaat ttgaaaaact tttatgctgt 4200

 agtctcatta gaatcatttt aaaagcactg ttcttgcatt tttcctagac 4250

 tacagagagt gttctttgtc attttttttc ctattctgtt gtgaagttta 4300

 ttgtttcagt tatttgaggg aaataacctc ttaatatgtt tattttcctg 4350

 aactaaagtt ttcatgtaga gaatacaatt aaatgttttg tgttatgacc 4400

 caaactggct ggaagtagag ttcagagagg gagaagggac aagaatcagt 4450

 gtgggcatct caggaaagtg gcgccagtgc tgggctccag ccttctccac 4500

 tggcatgatg ggtcctcaga ttctcctctg gataatgagg gtgttgggca 4550

 ctgtgagctc tgacttctgg ggaggatagg ccatcatgga ctccatacac 4600

 aattttgatg ggtatcagtt ctcataaaat acctgctaca atttatttat 4650

 tttgtagttg tttagaaaac tgtgagcagt tgggcattag taaattgtag 4700

 ttatatctta acgatcttgg gaatcattga aatatgagtt tttttccctc 4750

 actcctattt atttaattaa aaaattaggg aagttgttca ttcacagctg 4800

 tatattaata taaaatctct ttataaaatg attcagagaa aaggcagtag 4850

 tggtcactta ctgtgctaaa ataccttttt ctctaaaaat atttaagctt 4900

 tagggtttgt catagtttta ctttttaaat tatactttgt gtaacaattt 4950

 acgttaacta gaaaaattag atatataata agttttggta ctaagaaaca 5000

 tttacattct acactcatta gtcaaatgaa cttttctttc ccagtgctaa 5050

 cagattttgt ttcatgtgaa gaaaaataaa atacaaatga aataaaagtc 5100

 tagaaacagc aacaggaaac tcaccacaga aataaagaca taacccttga 5150

 taagtttgtg taagtgccag aattattgga agcaggtgac gaatgattaa 5200

 gaaaagcttt attgtgggga catgctttaa gaatcagctc tgtatttgtg 5250

 ccaaggagat caggtattgg tgtgcaaaca gatcccatta atactctgat 5300

 ttgaaccatg aattccacct actctgcgtt gaagccctcc agtagactga 5350

 tagatgtaat caaatgatca gctaccaagt ttaattcctt tgcctgtgtg 5400

 tagcaacagt tggtagtttt acaagttaag ttgatggtct ggctgcagat 5450

 aagagaaaga ctcagtgata ggtggtttgt gagtgaagta acttccacac 5500

 tgtcaagagt tgacagcata ttaattgtgt ggcattataa ttgtgagaaa 5550

 caaatgagag caaaatgtta ggtcctttga caagcatttt cctcctgttt 5600

 ttaaaaaggg ctttaagttg tttcctatgt aaggtaatct ttctttttta 5650

 gtattatcta agaaggatgg tagattatgt cattttggaa actattgtgt 5700

 cccttgtatt ttaaatattt caggaaaatg cctacgattg ttacaaagat 5750

 gtgtgtttta cttataacat aagctctgat tctccagtgg ccactgggcc 5800

 ttctctgtgc tctgtattca actgcagtat gaattacaga atgctgtgca 5850

 tgttcgttag taccaatacc atgtgtatgt ggtagaagtt gtaaccagtt 5900

 tctggatctg tatggtacta taaaatactt attttataat tctgtaaccg 5950

 tatggcagtg ttatgccaaa aatgtataaa gagcaatagt ttttgttgct 6000

 tactgctgta ttttaaaata ttgtttctaa aataatagag ttagagttcc 6050

 ttttgagtaa ttatttttaa gaactattgc caaatataca tcctgtaaaa 6100

 ctaataaaag ccactccatc ttagataaca ttttagcatt gtgctagagt 6150

 acattatggt gattttgcac gattaaaata tttttaaaga actagaaaaa 6200

 atgacttgct gttttcctgt cattaagcat gtatttttta tgattaacac 6250

 ataagactaa cattattttc ttttatcctc aaaaataaat attgtgaagg 6300

 gtgaatcat 6309

<210> 4426
<211> 171
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 43-144
<223> unknown amino acid

<220>
<221> Unsure
<222> 267-571
<223> Unknown amino acid

<400> 4426
 Met Ser Leu Trp Ser Ser Gly Leu Pro Ser Leu Ser Ile Ser Pro
   1               5                  10                  15

 Ala Val Leu Thr Ser Leu Pro Leu Ser Met Leu Thr Leu Lys Pro
                  20                  25                  30

 Pro Ser Phe Ser Ala Ser Val Cys Val Ser Ser Val Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 110                 115                 120

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 125                 130                 135

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa His Ile Arg Met Ile Tyr
                 140                 145                 150

 Ile Glu Ile Tyr Met Glu Gln Ser Gly Thr Ser Asn Cys Met Thr
                 155                 160                 165

 Ser Arg Phe Cys Phe Val
                 170

<210> 4427
<211> 3226
<212> DNA
<213> Homo sapien

<400> 4427
 ggcaggaatt tcggtagaac tggagtgacc tgtggaactg ctttagaatc 50

 taacctgctg tcttcgtgct ctgtgtgaag gggaagctgg ggggttagca 100

 tgaagtctgg ccttgtgtgc attggagctt ccaaggcact ttgaaatcat 150

 tccagtatat ttgggaagaa ttgagtgaat gagaatgctc ttccttattc 200

 tggtagattt gacttgttta taattctgca ctttagaaga aaaacagtgt 250

 taatctgtag ttgaaagaaa gcttagtaga tgagagagtt ctaggctact 300

 gtggcttttt ccagtagatt tagatgagat tatgtgtttt gaaatgtttt 350

 gtgggatccc ttagaaagca tcacttcagg gcagagacac tcaatattgc 400

 cagccagctt gggttctaaa gtgatttaat caaattcatg ctcctgatct 450

 tttttttccc ccttcctttg gctatgaaaa cccaaagccc ggagtgattg 500

 ttttctcctt gctttaagca gtgaagttat cctaatgcaa aagagcttag 550

 tagaaaatga gtggtttacc tttttttcta aaagtatatt ttcaagttta 600

 ttctggaatg tgatgtcttg gtcctcttaa aagcagatca gccatgactg 650

 aaactcaagg cttagctggt atctatgttg tgctacatta ggtgactaga 700

 agccacttct tagtgtaatc agctcctgtt tccctgtgag ccttagttat 750

 attttaattc agtggctttg agtcaaggcc ggttctaatt gaggggaccc 800

 agtgtgcttc agtgttaaga gtggggcaat gaagagtgaa ccccaatgaa 850

 gagtgatccc aactttggaa actatctggt cattcatgac cttaaaaagc 900

 tgccatggtg gtcaaatggc atgtgtttgc acaaaaatga ccgatgtgtt 950

 taaccaaagc tttgaaatgt gatgaagcca ccaacataag cacttgccta 1000

 acagaaatca gtatttcttc tacttagaag gcttggggcc cagggtaatg 1050

 aggcaccaga tgaagataag atctgcatca aggaattaaa tttccagttt 1100

 gtccttgggg ttctttctgc ttatgttttt tcccccccat ctggtaatag 1150

 tcctcttctg agaatgaaag gaggcacaga agttgcgaga aagacccagt 1200

 ccccagtctt tgccaccatt gcaccatggt tgtctcggag tcccttcacc 1250

 tgaccttttt agtcagctca gatctttttg tagtttgaga atagacctat 1300

 tcaagagcta tcagggttaa aagctgcact gaccaaagct gtacttttaa 1350

 aacacaaccc ctgggctagt gatgtctcta cttgctctat gagccttttg 1400

 ccagcctcag aataggcgag gtaaccttga atttcagggc cctggaaact 1450

 ctagctgaaa cctgcctttc ctaatgctca cacaagcacc aggtaccctg 1500

 agcttatact gagtccagtg gttcctattt atgtgtgtgt gtatgtgtgt 1550

 gtgttgagta acatgaaact tggcagtagc agagagcact gaagttcaca 1600

 tgcaagttct aatctaaagt taagcagtct cttatttgtt tcgggactct 1650

 gatttgactc tttttctgat gctttcggca tgtctgcagc ctgttctcct 1700

 agcctgctgc ttggagtcag gttgagcatc agtgagatga agacagtacc 1750

 ttttcctctc acattggcag aatagcacgc actagatgcc tgaccttgag 1800

 ctctagtctc ccctttaaat cttaccttgg cagtaacaca ttattcctca 1850

 ttcaataatt tcaatgctga aactgaactc tattactaat gccttccaat 1900

 cagagttcct gatggggatg cctgtgggat ggcccacacc tgggggacct 1950

 ggcagatggg gtgagttggg taaggaagat gatgcttagt tcctgataga 2000

 tgctacagat gtagtttggc atttcagttt ttgtccagtt tgattttcac 2050

 tggggtttga gtcacagcaa gctgtgtatg aacttgtgtt ttgtggtgac 2100

 acattaataa tcaaattgct aaaaccctga atctgcttat tcttcagctt 2150

 cacctctgca ctaacccctt acccttatgg tacgtcagga ttttaactag 2200

 tactgctttg ttgactttgg gaaatggtgc cactcaaaag caacttccta 2250

 acttgaggaa taactccttt gtagtttact ttctggtact ggttggtgcc 2300

 ttgtattggg atacagctat attcttagct caaatgtcct ctttttgaga 2350

 gcaaagtagt tatccaatgg tgagacgaga ccctgacgct catagaggcc 2400

 attccttcct gggtgtcgga ccagggctct gtgtcaggga aaaccttctg 2450

 ggtggacttt gtaagaatcc agtttccaag gttagattca catccttaat 2500

 cttgcagaga ctagaatttc acagctcgct ttggaacata ttccaattca 2550

 accagttaaa atcagaggac caagtcgtgg gggagggggg cggtgttgag 2600

 gagaggtatt tttaaagatc tggcaacttt tcaggattat ttgtggagaa 2650

 ctctaaggtt aagatcagga aataaaagac tgtgtgtgtg ggtgtgtgcg 2700

 tgtgtgtgtt caagtgccta aatcttgttt acctatcact ttaaaaaaat 2750

 aattgaagtg taagctaaat aaaatgcttg gagttttgcc tgggctagtg 2800

 agagttggtg caaattcttg tgtgtgtttg cataggaagg tgagatgacc 2850

 atctactaaa gaggaagtag ctaaatacag atctgtgggt gtttttaaaa 2900

 aaactcaacc tatctggtgt tttattttaa tggataaaaa tgtaattttt 2950

 ctaaggtagc aacttatttc caaattaata tagatgaaaa atagatacca 3000

 attagactaa attgaaagct ttttgttcta tatttgcata gcctttgaaa 3050

 tatttcttag tgcctaggag gtctggggat tcctctttcg tggtggtcac 3100

 taaccttact tgatgcagat aaaatcactt gtcaatgcaa aatgtgttag 3150

 aacttgataa agctttgagt ttgagaaata aaggtatatt taaaatttaa 3200

 ataaaacttg tcatttatgc tcattg 3226

<210> 4428
<211> 25
<212> PRT
<213> Homo sapien

<400> 4428
 Gly Arg Asn Phe Gly Arg Thr Gly Val Thr Cys Gly Thr Ala Leu
   1               5                  10                  15

 Glu Ser Asn Leu Leu Ser Ser Cys Ser Val
                  20                  25

<210> 4429
<211> 3983
<212> DNA
<213> Homo sapien

<400> 4429
 gtgccaaggc ggctgggggc ggcgagcggg gccgcgggcg cgcaccgact 50

 caagagccga ctgtcagcct cggcgggccg gagttctccg gcgctgggac 100

 aggggcgctg ggacaggggc gctgggggcg agccctggcg ggggccaggt 150

 ccgaggaccc tgggcgcggc ggccccgcca ggaggtccgg ccgcgagcgt 200

 gacctcacgg ggaggggcca gcgcggcggc ctgggcgctg agccgagcgc 250

 cgggagagca gcgcagaagc cgagccgcga ggagcgcact ccgtggcccc 300

 gatggagcgg tacaaagccc tggaacagct gctgacagag ttggatgact 350

 tcctcaagat tcttgaccag gagaacctga gcagcacagc actggtgaag 400

 aagagctgcc tggcggagct cctccggctt tacaccaaaa gcagcagctc 450

 tgatgaggag tacatttata tgaacaaagt gaccatcaac aagcaacaga 500

 atgcagagtc tcaaggcaaa gcgcctgagg agcagggcct gctacccaat 550

 ggggagccca gccagcactc ctcggcccct cagaagagcc ttccagacct 600

 cccgccaccc aagatgattc cagaacggaa acagcttgcc atcccaaaga 650

 cggagtctcc agagggctac tatgaagagg ctgagccata tgacacatcc 700

 ctcaatgagg acggagaggc tgtgagcagc tcctacgagt cctacgatga 750

 agaggacggc agcaagggca agtcggcccc ttaccagtgg ccctcgccgg 800

 aggccggcat cgagctgatg cgtgacgccc gcatctgcgc cttcctgtgg 850

 cgcaagaagt ggctgggaca gtgggccaag cagctctgtg tcatcaagga 900

 caacaggctt ctgtgctaca aatcctccaa ggaccacagc cctcagctgg 950

 acgtgaacct actgggcagc agcgtcattc acaaggagaa gcaagtgcgg 1000

 aagaaggagc acaagctgaa gatcacaccg atgaatgccg atgtgattgt 1050

 gctgggcctg cagagcaagg accaggctga gcagtggctc agggtcatcc 1100

 aggaagtgag cggcctgcct tccgaaggag catctgaagg aaaccagtac 1150

 accccggatg cccagcgctt taactgccag aaaccagata tagctgagaa 1200

 gtacctgtcg gcttcagagt atgggagctc cgtggatggc caccctgagg 1250

 tcccagaaac caaagacgtc aagaagaaat gttctgctgg cctcaaactg 1300

 agcaacctaa tgaatctggg caggaagaaa tccacctcac tggagcctgt 1350

 ggagaggtcc ctcgagacat ccagttacct gaacgtgctg gtgaacagcc 1400

 agtggaagtc tcgctggtgc tctgtcaggg acaatcacct gcacttctac 1450

 caggaccgga accggagcaa ggtggcccag caacccctca gcctggtggg 1500

 ctgcgaggtg gtcccagacc ccagccccga ccacctctac tccttccgca 1550

 tcctccacaa gggcgaggag ctggccaagc ttgaggccaa gtcttccgag 1600

 gaaatgggcc actggctggg tctcctgctc tctgagtcag gctccaagac 1650

 agacccagaa gagttcacct acgactatgt ggatgccgat agggtctcct 1700

 gtattgtgag tgcggccaaa aactctctct tactgatgca gagaaagttc 1750

 tcagagccca acacttacat cgatggcctg cctagccagg accgccagga 1800

 ggagctgtat gacgacgtgg acctgtcaga gctcacagct gcggtggagc 1850

 ctaccgagga agccacccct gttgcagatg acccaaatga gagagaatct 1900

 gaccgggtgt acctggacct cacacctgtc aagtcctttc tgcatggccc 1950

 cagcagtgca caggcccagg cctcctcccc gacgttgtcc tgcctggaca 2000

 atgcaactga ggccctcccg gcagactcag gcccaggtcc caccccagat 2050

 gagccctgca taaagtgtcc agagaacctg ggagaacagc agctggagag 2100

 tttggagcca gaggatcctt ccctgagaat caccaccgtc aaaatccaga 2150

 cggaacagca gagaatctcc ttcccaccga gctgcccgga tgccgtggtg 2200

 gccaccccac ctggtgccag cccacctgtg aaggacaggt tgcgcgtgac 2250

 cagtgcagag atcaagcttg gcaagaatcg gacagaagct gaggtgaagc 2300

 ggtacacaga ggagaaggag aggcttgaaa agaagaagga agaaatccgg 2350

 gggcacctgg ctcagctccg gaaagagaaa cgggagctaa aggaaaccct 2400

 actgaaatgc acagacaagg aagtcctggc gagcctggag cagaagctga 2450

 aggaaattga cgaggagtgc cggggcgagg agagcaggcg cgtggacctg 2500

 gagctcagca tcatggaggt gaaggacaac ctgaagaagg ctgaggcagg 2550

 gcctgtgacg ttaggcacca ccgtggacac cacccacctg gagaatccca 2600

 aagctgtcac acctgcctct gccccagact gtaccccagt caactctgca 2650

 accacactca agaacaggcc tctctcggtc gtggtcacag gcaaaggcac 2700

 tgtactccag aaagccaagg aatgggagaa gaaaggagca agttagaaaa 2750

 caagcttcat ctaaagactc tcatgtcaat gtggaccttg gtgacaatcc 2800

 tgctttgtta aagcaaaaac tatgcgaaag ggtgagtctg tttagaagaa 2850

 aaagcaaaga ctgaggtact gtgaatggag agcttcagct aagaggaggc 2900

 tctgtccctt ttcagagcca aaggaaataa tacaacaaaa aggaggcttc 2950

 tttggagacc taagtctatt ggatgtaaac aagacgttgt atttagggat 3000

 gttctgtgtt tctttctttt ttgaagttgt catcaattgc tttactaaga 3050

 tttttaaata gtgaaaacct cctgtttaga ctttggtgga agatgaatca 3100

 aggaagcagg gccctgtctt atgggtcaca tgtctttggt gagtgagaag 3150

 acctaaactc ctggccatca tctcttatcc aatacttagc agttggggat 3200

 taaaccatcc ttgccttcag ttctctccaa tattaccagg cccaactcag 3250

 tcttcagtga ttttaaacag cattgacatc atctgtaaaa ccatcatctg 3300

 taaaaccatc tatgacatga gttttgagaa acaataatgg ggaaaatatt 3350

 tgggaccaag ctgaagcact aatcccacta agttaaagac ttctttccag 3400

 tccaaggcag gcctgaatca actgtcttta aataaaattt taagtgatgc 3450

 tgtattatat ataggaaaaa atgcttaaaa tcctgtcatt tagaacagtg 3500

 aaaagtatct tttgagatta aagtgactct ttactgtagg aaaaatatta 3550

 ctctgtgttt acagattcat tgctgtggtc aggccatttt taagggaaga 3600

 gttatttaat ataaatagtc tctgatttta agttctgttt aatgttcatt 3650

 ctccttccaa gaacaaagtg gtgatttttg gttagggtga tcgccctctt 3700

 aaaattggca gtgctgttcc ttgtgctgcc cctgtctttt cctctgatgg 3750

 catttttttt tttttttttt tttaacacag gttgaaacat ttcatctatt 3800

 atctctgcct catttctgga gggttgtgta tcagttctct aacacttgtt 3850

 cctgagaact aaatgtcttt tttattctta tttcctctct cataaacatt 3900

 tggtgacctt ttaccaagtg gtgagttagg ttttttaaaa taaaatgttc 3950

 attgtatttg aaaaaaaaaa aaaaaaaaaa aaa 3983

<210> 4430
<211> 814
<212> PRT
<213> Homo sapien

<400> 4430
 Met Glu Arg Tyr Lys Ala Leu Glu Gln Leu Leu Thr Glu Leu Asp
   1               5                  10                  15

 Asp Phe Leu Lys Ile Leu Asp Gln Glu Asn Leu Ser Ser Thr Ala
                  20                  25                  30

 Leu Val Lys Lys Ser Cys Leu Ala Glu Leu Leu Arg Leu Tyr Thr
                  35                  40                  45

 Lys Ser Ser Ser Ser Asp Glu Glu Tyr Ile Tyr Met Asn Lys Val
                  50                  55                  60

 Thr Ile Asn Lys Gln Gln Asn Ala Glu Ser Gln Gly Lys Ala Pro
                  65                  70                  75

 Glu Glu Gln Gly Leu Leu Pro Asn Gly Glu Pro Ser Gln His Ser
                  80                  85                  90

 Ser Ala Pro Gln Lys Ser Leu Pro Asp Leu Pro Pro Pro Lys Met
                  95                 100                 105

 Ile Pro Glu Arg Lys Gln Leu Ala Ile Pro Lys Thr Glu Ser Pro
                 110                 115                 120

 Glu Gly Tyr Tyr Glu Glu Ala Glu Pro Tyr Asp Thr Ser Leu Asn
                 125                 130                 135

 Glu Asp Gly Glu Ala Val Ser Ser Ser Tyr Glu Ser Tyr Asp Glu
                 140                 145                 150

 Glu Asp Gly Ser Lys Gly Lys Ser Ala Pro Tyr Gln Trp Pro Ser
                 155                 160                 165

 Pro Glu Ala Gly Ile Glu Leu Met Arg Asp Ala Arg Ile Cys Ala
                 170                 175                 180

 Phe Leu Trp Arg Lys Lys Trp Leu Gly Gln Trp Ala Lys Gln Leu
                 185                 190                 195

 Cys Val Ile Lys Asp Asn Arg Leu Leu Cys Tyr Lys Ser Ser Lys
                 200                 205                 210

 Asp His Ser Pro Gln Leu Asp Val Asn Leu Leu Gly Ser Ser Val
                 215                 220                 225

 Ile His Lys Glu Lys Gln Val Arg Lys Lys Glu His Lys Leu Lys
                 230                 235                 240

 Ile Thr Pro Met Asn Ala Asp Val Ile Val Leu Gly Leu Gln Ser
                 245                 250                 255

 Lys Asp Gln Ala Glu Gln Trp Leu Arg Val Ile Gln Glu Val Ser
                 260                 265                 270

 Gly Leu Pro Ser Glu Gly Ala Ser Glu Gly Asn Gln Tyr Thr Pro
                 275                 280                 285

 Asp Ala Gln Arg Phe Asn Cys Gln Lys Pro Asp Ile Ala Glu Lys
                 290                 295                 300

 Tyr Leu Ser Ala Ser Glu Tyr Gly Ser Ser Val Asp Gly His Pro
                 305                 310                 315

 Glu Val Pro Glu Thr Lys Asp Val Lys Lys Lys Cys Ser Ala Gly
                 320                 325                 330

 Leu Lys Leu Ser Asn Leu Met Asn Leu Gly Arg Lys Lys Ser Thr
                 335                 340                 345

 Ser Leu Glu Pro Val Glu Arg Ser Leu Glu Thr Ser Ser Tyr Leu
                 350                 355                 360

 Asn Val Leu Val Asn Ser Gln Trp Lys Ser Arg Trp Cys Ser Val
                 365                 370                 375

 Arg Asp Asn His Leu His Phe Tyr Gln Asp Arg Asn Arg Ser Lys
                 380                 385                 390

 Val Ala Gln Gln Pro Leu Ser Leu Val Gly Cys Glu Val Val Pro
                 395                 400                 405

 Asp Pro Ser Pro Asp His Leu Tyr Ser Phe Arg Ile Leu His Lys
                 410                 415                 420

 Gly Glu Glu Leu Ala Lys Leu Glu Ala Lys Ser Ser Glu Glu Met
                 425                 430                 435

 Gly His Trp Leu Gly Leu Leu Leu Ser Glu Ser Gly Ser Lys Thr
                 440                 445                 450

 Asp Pro Glu Glu Phe Thr Tyr Asp Tyr Val Asp Ala Asp Arg Val
                 455                 460                 465

 Ser Cys Ile Val Ser Ala Ala Lys Asn Ser Leu Leu Leu Met Gln
                 470                 475                 480

 Arg Lys Phe Ser Glu Pro Asn Thr Tyr Ile Asp Gly Leu Pro Ser
                 485                 490                 495

 Gln Asp Arg Gln Glu Glu Leu Tyr Asp Asp Val Asp Leu Ser Glu
                 500                 505                 510

 Leu Thr Ala Ala Val Glu Pro Thr Glu Glu Ala Thr Pro Val Ala
                 515                 520                 525

 Asp Asp Pro Asn Glu Arg Glu Ser Asp Arg Val Tyr Leu Asp Leu
                 530                 535                 540

 Thr Pro Val Lys Ser Phe Leu His Gly Pro Ser Ser Ala Gln Ala
                 545                 550                 555

 Gln Ala Ser Ser Pro Thr Leu Ser Cys Leu Asp Asn Ala Thr Glu
                 560                 565                 570

 Ala Leu Pro Ala Asp Ser Gly Pro Gly Pro Thr Pro Asp Glu Pro
                 575                 580                 585

 Cys Ile Lys Cys Pro Glu Asn Leu Gly Glu Gln Gln Leu Glu Ser
                 590                 595                 600

 Leu Glu Pro Glu Asp Pro Ser Leu Arg Ile Thr Thr Val Lys Ile
                 605                 610                 615

 Gln Thr Glu Gln Gln Arg Ile Ser Phe Pro Pro Ser Cys Pro Asp
                 620                 625                 630

 Ala Val Val Ala Thr Pro Pro Gly Ala Ser Pro Pro Val Lys Asp
                 635                 640                 645

 Arg Leu Arg Val Thr Ser Ala Glu Ile Lys Leu Gly Lys Asn Arg
                 650                 655                 660

 Thr Glu Ala Glu Val Lys Arg Tyr Thr Glu Glu Lys Glu Arg Leu
                 665                 670                 675

 Glu Lys Lys Lys Glu Glu Ile Arg Gly His Leu Ala Gln Leu Arg
                 680                 685                 690

 Lys Glu Lys Arg Glu Leu Lys Glu Thr Leu Leu Lys Cys Thr Asp
                 695                 700                 705

 Lys Glu Val Leu Ala Ser Leu Glu Gln Lys Leu Lys Glu Ile Asp
                 710                 715                 720

 Glu Glu Cys Arg Gly Glu Glu Ser Arg Arg Val Asp Leu Glu Leu
                 725                 730                 735

 Ser Ile Met Glu Val Lys Asp Asn Leu Lys Lys Ala Glu Ala Gly
                 740                 745                 750

 Pro Val Thr Leu Gly Thr Thr Val Asp Thr Thr His Leu Glu Asn
                 755                 760                 765

 Pro Lys Ala Val Thr Pro Ala Ser Ala Pro Asp Cys Thr Pro Val
                 770                 775                 780

 Asn Ser Ala Thr Thr Leu Lys Asn Arg Pro Leu Ser Val Val Val
                 785                 790                 795

 Thr Gly Lys Gly Thr Val Leu Gln Lys Ala Lys Glu Trp Glu Lys
                 800                 805                 810

 Lys Gly Ala Ser


<210> 4431
<211> 2088
<212> DNA
<213> Homo sapien

<400> 4431
 gattcgaatc agtgttaaat cagaaaatca gggttttcta ggaaattggg 50

 aattagttgc cagaaaggaa actgaactat gcagaaggag ttaagagctg 100

 ggatgaggct ggatggggtg actgacagtc cagatcattg aaacagattg 150

 ggtcgtcgga aactggtcca gatgaggctg gatggggtga ctgacagtct 200

 ggatcattga aactgattag gtcgtcagaa acgggtccag acgaggatga 250

 ggctgaggct ggatggggtg actgacagtc tggatcattg aaactgattg 300

 ggtggttggt cagaaacggg tccagatgag gatgaggctg aggctggatg 350

 gggtgactga cagtctggat cattgaaact gattgggtgg ttggtcagaa 400

 acgggtccag atgaggatga ggctggatgg ggtgactgac agtctggatc 450

 attgaaactg attgggtcgt cagaaactgg tccagatgag gctgggtggg 500

 gtgactgaca gtttggatca ttgaaactga ttgggtggtc agaaactggt 550

 ccagatgagg atgtggctgg atggggtgac tgacagtctg gatcattgaa 600

 actgattggg tggtcagaaa ctggtccaga tgaggatgtg gctggatggg 650

 gtgactgaca gtctggatca ttgaaactga ttgggtggtg agaaatgggt 700

 ccagatgagg atgaggctgg atggggtgac tgacagtctg gatcattgaa 750

 actgattggg tggtgagaaa tgggtccaga tgaggatgag gctggatggg 800

 gtgactgaca gtctggatca ttgaaactgg tccactatga cgcagcaggg 850

 gcagtttggc agagcatcct cttcccttgt ccttgtgaaa gaacacagga 900

 aacatttggg ttttacagct tttcacaccc tactatcagg catcagaatc 950

 aaaattagtt actaaattgg gtgaattttt ggaaacctgc atttctatgc 1000

 atctgctatt ccagaaaaaa atgggaatgt attacaggag agttacctca 1050

 cagtgtctta tgttgtggaa cctgaaacat aaccacgtgt tttcttatat 1100

 gatcatttgt gttgatactg cttttatttg agtttatgaa cagaaataga 1150

 aagtatggtg cttgggtttt gccctttctt actcctgaaa gttaaatcag 1200

 aagacactga tttcattttg tgaaatttag ctcagagact attgatcttt 1250

 tgtttcatta atatgaacaa ctattagtaa aaaatagctt taacagcatt 1300

 tctgctgata tctagtaatc tattctttta atgtgaaaat aagataaaat 1350

 gtcctggagc taattctagc ttaaatttgc cagtatttct gtatgtcatt 1400

 aagttttttt cctctaaggt tggtaataga attttgttaa tctttgcata 1450

 cctgatggca tctatgtcaa tgctgattgg gtaattataa attctgtgct 1500

 aatttaaaac ttaatttgcc tcttaaggtg attgtcctct gagtaatgat 1550

 tgtagttaaa tgaagtatag cttgcaacta tactatcaca tgggtcgtta 1600

 agtaaaaata aataaaccaa atttgtctga gacaggctaa gatcaatctt 1650

 ctcatcaaac caatttttct ctaagagcaa tttcactttc agttttaggg 1700

 tggacattct tgaatgcctc aaattaaacg ttatctattt aatcttcctg 1750

 gaatagtctg tgaccaaaaa ggagggtgtg atatatttag gtgtaaatat 1800

 atcacatata tggtgtgata tatttgggat ttatatattc agctcattct 1850

 ctgtgaagaa gtcttcctga ctaaaattgg tttcaagata aactaatttc 1900

 tgttagtatt tctactctgc ctaccatgta tgcctttttg ttagaaacta 1950

 ataaatgtat cagtcactag caggtactgg tcctttttcc tctcattttt 2000

 gtggaaagga tatgcaaaca ctgaatttct cagggagtac taaggctgtg 2050

 cagaggctga gaatctgaaa aataaaatac taaaaatt 2088

<210> 4432
<211> 30
<212> PRT
<213> Homo sapien

<400> 4432
 Ile Arg Ile Ser Val Lys Ser Glu Asn Gln Gly Phe Leu Gly Asn
   1               5                  10                  15

 Trp Glu Leu Val Ala Arg Lys Glu Thr Glu Leu Cys Arg Arg Ser
                  20                  25                  30

<210> 4433
<211> 703
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 505-523
<223> Unknown base

<400> 4433
 gtaataaccc agatatgagt aggtcacata aagtatatct tttttaaaaa 50

 aagaattcaa ttatgtctta ttttgggggg tatatttccc cagaagatat 100

 ttttctggca tgtggtctgt aaacacagca tgattcatat tttttatgtt 150

 tcatgctact cattttgttt aattaccaac aaacatgggg actttggctt 200

 tttgacttat ttgcaacaag catgaaattg ttaaatttac cttttatcaa 250

 ttgtaatcat cctatgccaa catattatca taaattcata gaaatatttt 300

 taaaaataaa taacagacat tgaaatccaa ttcttagata atactcccag 350

 aacagccaat ggtaaatgcc ctatacttga gtcttactta gatgctgtgg 400

 taatgcacca ttttagaaga tgaatgatac tgctatttct cttcagggaa 450

 acataatgga taaagaaatg taactgccgg gcagcaagct tctaagtgaa 500

 acctnnnnnn nnnnnnnnnn nnnggagaaa atgtgtagtc atcaagtgaa 550

 aataggaaag gatctatgat ttatgatgtc ttaatagacc ctaaattgtt 600

 ctttaattac agagtggcag tctctgaagt catttgtgag cttgtatgac 650

 ttttgtattt agcatgttgc atgctcacat aattgaaaat taaaagtaac 700

 aca 703

<210> 4434
<211> 14
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 505-523
<223> Unknown amino acid

<400> 4434
 Asn Asn Pro Asp Met Ser Arg Ser His Lys Val Tyr Leu Phe
   1               5                  10

<210> 4435
<211> 1752
<212> DNA
<213> Homo sapien

<400> 4435
 catatttgtg taagtttgta tatgtgtagg gctgtgtagg tatgtgtata 50

 tacagccata ttctaagtgt atatttatta aaatagattg catgttgcaa 100

 tacagttttc tgaaaggggt ctcattgact attaaataaa tgactactac 150

 taaacttgtc tgtagtcatt aatcttaaaa ttacctgaaa atctgatgac 200

 agctgccttc cctaacttta atgtattagg ttggcacaaa attaattgcg 250

 gtttttgcca ctattaatgg caaaaaccgc aattattttt gtaccaacat 300

 aatacacctt tcatattatg tattatcttg cttaatgggt tttatcttga 350

 ttatccagtt acttccatcc tcttcccaat gttaatttgc aatagtttta 400

 aaatgggaac aaatgaatca atcatcagat agttaaaatg aaattaaatc 450

 agctgcctaa taatttatgg aattcattgg aatgtgctta aaatgctaaa 500

 gtgtatgtca ttgaacatga aatctttttt caggcacata cattgttggt 550

 attgatgact ttttaaaacc tgtgggataa acttgcactg cacacggaag 600

 ttttattctt gtatatttag atttgtatgc ttgtgagtaa aaatgtgcat 650

 ttgtaaatac tgtgttttta ggttgaatca attaagtctt aaaactgtaa 700

 atttattaag cttgttgcca gtaggtttaa gaaaatcatg atctcacatg 750

 cctcactttg acatttatca tgccttttat taaaaatatc ccttaggaac 800

 agtaagtttg ccttaactct ctgcatggtt taaaaagcca ttggttttgt 850

 gtgtgtttac agtaattatg cagatgacta aatgagttga cacagtaaaa 900

 ttacttccat atggtacagt aacaacctaa ctcccttcta cctgatgtaa 950

 ccatttacaa attatagtta ttgtaccagt ctttcaacat ttcagggtta 1000

 atctgaccta tgcagaattc tagtgtgaat ttattgtgaa aatgctaaat 1050

 gaaacaattt gtcagaaatt atgtacaatt ttcattacct tcaaaatgga 1100

 tcttttgcac tgtctgagag tatatatttt tgcaactcaa gacttggtac 1150

 tagttttaat acttaacact tactgaccca acagaagttt ggaattacct 1200

 tgcatataaa aattgaggtt gaataaaatg aaaaattgtt gttttctgtt 1250

 acattaagcc tcttgaaatc tgtaatcttt agaatcccaa tattttgttt 1300

 tttccattcc ttcactcgta acttgaactc aagttttcac ttactgacgc 1350

 gcttcccatt aaaaaaaatc tgtaaagatc tctaccttga aaactttagt 1400

 ctgctgctgc catttagata ttgggactga tttcttgtta taaattttta 1450

 aaggcttttt ccaataccca ccacagagag ggtaccacta aaaatttaca 1500

 agacaaaaac attattatgg aaagatttag aagtacctgg aatgacttgt 1550

 agcactgtat gcaactttaa tcctgataac ttctaaaagc aatctttcaa 1600

 attagtccag attactcagc agtaccttat attggtttgg ggttcgatag 1650

 cgattttttt ttcttccaac gaacgaattg tacaggttga tcacaacctg 1700

 catagttaac gacatgtcag aatgacttgc gtgtgtgtgg agaactgggt 1750

 at 1752

<210> 4436
<211> 10
<212> PRT
<213> Homo sapien

<400> 4436
 Met Thr Cys Val Cys Val Glu Asn Trp Val
   1               5                  10

<210> 4437
<211> 1846
<212> DNA
<213> Homo sapien

<400> 4437
 aagaccctga tggaagtgga ggagaatcat ctcaggcaaa ctttttgtgt 50

 gccagtaaca gaaaccctct ttgtgtgatc acatgcaaag tataggatat 100

 ttgcaatata gccatgggga ggagtgcagg gcccaagggt agattttagc 150

 caggcctccc aggaacagaa ctcggatccg aaaagcccag agaagctaga 200

 gctgcccctc caacactctc ggatccacat ggtctgtgtt ctctagaccc 250

 ccctgcatgt tagcggtgtt ctctctctgt ggactgactg tccttctcag 300

 tgaacatgtc cacccgacag ctcctgagtt tatatcatct caaccctcac 350

 aacccacaga ggctgtgtct cctagtcaca gctttaaatt actggaaaaa 400

 taaatgactg gccaaacttg gagcaggtgt ccatcccagc cctgtgtagt 450

 tagagcagga atcaagatct caacacaaat gtggctgcca agcactcagc 500

 cccggggcga ggggtcaagt tcttctcaga gaaagaggaa taagttggtt 550

 ctcagaagac atcacaagat acgtgtgtac ccaacaatct ctgatctctg 600

 ctgatctttt gcttagacgt taacttgatg catcattgga aaggtgtttc 650

 tctcatctct gtcctaaggc ttgataaagt cattaaaatt gtgttctttt 700

 gactaaagaa atatgctttt tttttactgt tgcatatact accctgaagt 750

 cactggaact tctaggagta attccagagc ttttagattt atgcacctgc 800

 gtgtatactc acatttgttt ctagtctcaa ggtacgtagt cttttatttt 850

 aaaaaacaag ttgtcctcct gcattcttga tctttcactc tcttttagaa 900

 cagacatcca gtagtctcct gtcctttgta tccaaactct ccctttttgc 950

 agggtcaccc tacaaatcat aagcatgtca tctctcctat ataacaagaa 1000

 catcaaatcc tctgtctgtc cttgacccag tctcccttcc acccaagctc 1050

 ctggtcacgc tctctgagag tgtctacgtg gactgcctcc agatcccctc 1100

 ttcccatcca ctctctttcg gttttaattt ttaaccaaat tatgttatag 1150

 tttaaagagt caaatatttc tacaatattt gctacagaaa taccagtttc 1200

 cagccccatc tcccaccata tcctcaccct tacagaaaat aactttcaat 1250

 tgttctaata tgttttgttg gtattaacct cccatctcta aataacatgt 1300

 ttgtgttgct acatctagat ttttcagctt taggctttat ctctttacct 1350

 cctgctgtgg aagaggggga tttagatttt tttcatcctc aaagaacatc 1400

 atgccccctt tcccatgccc tttcttttaa tgtgactata ttgtaatttt 1450

 tacaatatag taaaagttac tgtgtttact atgtttctat caatatgacc 1500

 atgtaatggc aaaccataga gcaagccatg ctcactcttc cttttctaga 1550

 cgacttcgtt ttctctggag tatatagttg tcctgttttc ctttgtgtgg 1600

 ctgtatttgt acttattatt aatgaatcac aaaattcctc acagtacaat 1650

 caaacacatc aggtattctg tcaattttat caccagatat aactctccca 1700

 gaaccttctg tctgctccat tcttaactcc ttgcccttga tgatacagcg 1750

 gtcactctga gatcactctt cgccatcctc gtcaggattt acctatcctc 1800

 cgagttggat cttctgcttc ttgtatccag tcattgccct tttgtg 1846

<210> 4438
<211> 1704
<212> DNA
<213> Homo sapien

<400> 4438
 aaatatccta actaacttgt taataaggaa agaaaccaga tttgcttaaa 50

 tctgttcaag gctgacattc tgaaattcta aactggaaat aacttcccag 100

 agtatttgga aaggttctaa gtacaaggat caggcctaaa atagctcctt 150

 gggaaagaaa tttccttttt gatgagaaaa cttaaaatac tgtttttggt 200

 aatgtaagca gttaaaaaca tgactttaga aagacagctt aatgcgtatt 250

 caagcaaacc tttgttttgt tgcttttgct tttgtttgta gaagagagag 300

 gaagttatta taccaaaaag taatagtata tgtaactttg agtgaggcta 350

 cttatatctt agaatgggta tccttgaact atatctaccc caccatggct 400

 taaaaaaatc agtggtatat attgagaatg tcagtcatga gcttagtgtt 450

 taagtaacac atcccactta cagttgtttg catgattagt cttgtgtatc 500

 atgatgttca actttgcttt tgctgtgcca gttcaaaaat atcttttttg 550

 ctaaaaactc ttaaaattca tgacataagt tttgttttga tcacccggtt 600

 ttatatagta tttctgggac caaaaaattt aaatatacct ttttaatata 650

 aaacagaagt ttgaagctgg aaagatagtg tttatggaag atttgtgtgc 700

 ttttgtgttt tttaaacccg tcaggctgct ggtaaggcag tttctagggc 750

 tcacttttcc tccttacctc ttgactagtg tagcatgtgg tatgtttaaa 800

 atatttcatt ttctgcttcg taattctaag gtcaacacta tactgtatgt 850

 agacaggaga gctgatttgt atattttagt tatttggtct aatcaagcat 900

 aactaaaggg acttcttttt tgatactttt ctcaaattaa gtttaaatat 950

 agtatacggg ccacatttca tgtctttgaa agtgttgtac attactgtaa 1000

 accaagtact ctgtctacac cagagggtgc tttaactgca aaatatttga 1050

 gaaacaattc agtctctcaa acattttggc acagttcatc actccagttt 1100

 gttactttct tgagaatagt ccattttttg tttttgttat tataccgtat 1150

 gttctggtca ttggaaacag aacagctcat agttgggtga tgtaatataa 1200

 taacagtaat ataacctagt agtcattttg cttcaagtaa tttaattaga 1250

 tagcaaaatc actgcggttt gtttattaca cttgtagggc tttttgtctt 1300

 actcagtgac catcactacg aatgtcttac attgaagcac agactgcaga 1350

 gcacttgtta acttagtcct cctgcataat gcactcgtga aaagtagtgc 1400

 ttgctaggtg tttgaagatt ttatgatccg tgtgcttggg ctcgttgagt 1450

 tatttgtaaa ataaacattt agtttgagtt gatgcagtaa gttttttgga 1500

 ctagtagtat ccaggtccct actctactga aaatataatc ttcactatct 1550

 ccccttaagt cagaggagat gtagcattta gaacaccttg agacatgaca 1600

 ttgtaaaata gcttgtttta tgttcctgaa gctatcttgt tctctgttaa 1650

 agctactaat tgtctcagtg taagttttaa ataaacatat ttctttaaag 1700

 ctgg 1704

<210> 4439
<211> 15
<212> PRT
<213> Homo sapien

<400> 4439
 Asn Ile Leu Thr Asn Leu Leu Ile Arg Lys Glu Thr Arg Phe Ala
   1               5                  10                  15

<210> 4440
<211> 2937
<212> DNA
<213> Homo sapien

<400> 4440
 gctggaagca acagatgggg actgcagagg aggtggtggt attgggatag 50

 tgctgcagcc aagaacttaa cgactgaaag taactgggat atcttcataa 100

 ttatctgaag gtcacagtgg gagaacaaaa ttaaaagaac tgagaagact 150

 tacaagagaa cctcctaaga gtcacccaaa caatcggctg agaatgagaa 200

 gaggttcaag tgattcttgt gcctcaggct cccaagtagc tgggactaca 250

 gtagctgggc cagcacaccc agaaagcctc acattgtgca gtggagaagc 300

 tgagagaaga ggaaaagagg agtggccaga ctcccaccac tacccaggac 350

 caactcctgc tcctgaatct tctgatgggc cccacaaggt gacagtgctg 400

 gctacaatgc tatccagccg gtggtggcca agttcctggg ggatcctagg 450

 gctgggcccc cgaagccctc ctcggggatc ccagctctgt gccctctatg 500

 cctttactta tactggggca gatggccagc aggtgtctct ggctgaaggg 550

 gataggttcc tactgcttcg aaagaccaac tccgactggt ggttggcaag 600

 acgcctagaa gctccctcca cctctcgacc catcttcgtc ccagcagcct 650

 atatgataga ggaatccatc ccttcccaga gtccaactac cgtcatcccc 700

 ggccaattgc tctggactcc tgggccgaag ttgtttcatg gttccctgga 750

 ggagttgtct caggccctcc caagcagggc tcaggctagc tcggagcagc 800

 ctcctccact tccccgcaaa atgtgtagga gcgtcagcac tgacaatctg 850

 agccccagct ttctgaagcc tttccaggaa ggaccaagcg gaagatccct 900

 ctcccaggaa gacttgccgt cagaagccag tgccagcaca gcaggccccc 950

 agcccctcat gtcagagccc cctgtgtact gtaacctggt ggaccttcgc 1000

 cgctgtcctc ggtccccacc cccaggccct gcatgccccc tgctgcagag 1050

 gctggatgcc tgggagcagc acctggaccc caactctgga cgctgcttct 1100

 acataaattc actgactggc tgcaagtcct ggaagccccc gcgccgcagt 1150

 cgcagcgaga cgaaccctgg ctccatggag gggacacaga ccctgaagag 1200

 gaacaatgat gtcctgcaac ctcaggcaaa gggcttcaga tctgacacag 1250

 ggaccccaga accgcttgac ccacagggtt cactcagcct cagccaacgc 1300

 acctcgcagc ttgaccctcc agccttgcag gcccctcgac ctctgccgca 1350

 gctcctggac gacccccatg aggtggaaaa gtcgggtctg ctcaacatga 1400

 ccaagattgc ccaagggggg cgcaagctca ggaagaactg gggcccgtct 1450

 tgggtggtgt taacgggtaa cagcctggtg ttctaccgag agccaccgcc 1500

 gacagcgccc tcctcaggct ggggaccagc gggtagccgg cccgaaagta 1550

 gcgtggacct gcgcggggcg gccctggcgc acggccgcca cctgtccagc 1600

 cgccgcaacg tcctgcacat ccgcacgatc cctggccacg agttcctgct 1650

 gcagtcggac cacgagacag agctgcgagc ctggcaccgc gcgctgcgga 1700

 ctgtcatcga gcggctggtt agatgggtgg aggcccggag ggaggctccg 1750

 accggccggg accaagggag tggggatcgg gagaaccccc tggagctgcg 1800

 tctgtcgggc tctggacccg cggagctgag cgccggggag gacgaagaag 1850

 aggagtcgga gctggtgtcc aagccgctgc tgcgcctcag cagccgccgg 1900

 agctccattc gggggcccga aggcaccgag cagaaccgcg tgcgcaacaa 1950

 actaaagcgg ctcatcgcga agagaccgcc cttacaaagc ctgcaggagc 2000

 ggggtctgct ccgagaccag gtgttcggct gccagttgga atcactctgc 2050

 cagcgggaag gagacacggt gcccagcttt ttgcggctct gcattgctgc 2100

 tgtggataaa agaggtctag atgtggatgg catttatcgg gtgagcggga 2150

 acttggcagt ggtccagaag cttcgctttc tggtggacag agagcgtgcg 2200

 gtcacctccg atgggaggta tgtgttccca gaacagccag gacaagaagg 2250

 tcggttagat ttggacagta ctgagtggga tgacattcat gtggtcaccg 2300

 gagccctgaa gctttttctc cgggagctgc cccagcctct ggtgccacca 2350

 ctgctgctgc cccatttccg tgctgccctt gcactctccg aatcagagca 2400

 gtgcctctct cagatacaag aattaatagg ctcaatgcca aagcccaacc 2450

 atgacactct acggtacctc ctggagcatt tatgcagggt gatagcacac 2500

 tcagataaga atcgcatgac accccacaac ctgggaattg tgtttggacc 2550

 aaccctgttt cggccagagc aggagacatc tgacccagca gcccatgctc 2600

 tctacccagg gcagctggtc cagctgatgc tcaccaactt caccagcctc 2650

 ttcccctgat gcagggaagg aagaagagaa aacatatttc cggtcatctc 2700

 tggtggtgag aggctggtgt tctgttttga ggatatccct ttaaatctcc 2750

 caaatgactg tctctatctt catgagtgtg acttgaggtg ttgggatggg 2800

 tgagggagct tctctaaaga ggaaagtgag tggattaacc cctgcttctc 2850

 ttcttgttcc ctgttatcat tcctccccaa cataataata cataaagtgg 2900

 catggtattt ttaaaaaaaa aaaaaaaaaa aaaaaaa 2937

<210> 4441
<211> 750
<212> PRT
<213> Homo sapien

<400> 4441
 Met Leu Ser Ser Arg Trp Trp Pro Ser Ser Trp Gly Ile Leu Gly
   1               5                  10                  15

 Leu Gly Pro Arg Ser Pro Pro Arg Gly Ser Gln Leu Cys Ala Leu
                  20                  25                  30

 Tyr Ala Phe Thr Tyr Thr Gly Ala Asp Gly Gln Gln Val Ser Leu
                  35                  40                  45

 Ala Glu Gly Asp Arg Phe Leu Leu Leu Arg Lys Thr Asn Ser Asp
                  50                  55                  60

 Trp Trp Leu Ala Arg Arg Leu Glu Ala Pro Ser Thr Ser Arg Pro
                  65                  70                  75

 Ile Phe Val Pro Ala Ala Tyr Met Ile Glu Glu Ser Ile Pro Ser
                  80                  85                  90

 Gln Ser Pro Thr Thr Val Ile Pro Gly Gln Leu Leu Trp Thr Pro
                  95                 100                 105

 Gly Pro Lys Leu Phe His Gly Ser Leu Glu Glu Leu Ser Gln Ala
                 110                 115                 120

 Leu Pro Ser Arg Ala Gln Ala Ser Ser Glu Gln Pro Pro Pro Leu
                 125                 130                 135

 Pro Arg Lys Met Cys Arg Ser Val Ser Thr Asp Asn Leu Ser Pro
                 140                 145                 150

 Ser Phe Leu Lys Pro Phe Gln Glu Gly Pro Ser Gly Arg Ser Leu
                 155                 160                 165

 Ser Gln Glu Asp Leu Pro Ser Glu Ala Ser Ala Ser Thr Ala Gly
                 170                 175                 180

 Pro Gln Pro Leu Met Ser Glu Pro Pro Val Tyr Cys Asn Leu Val
                 185                 190                 195

 Asp Leu Arg Arg Cys Pro Arg Ser Pro Pro Pro Gly Pro Ala Cys
                 200                 205                 210

 Pro Leu Leu Gln Arg Leu Asp Ala Trp Glu Gln His Leu Asp Pro
                 215                 220                 225

 Asn Ser Gly Arg Cys Phe Tyr Ile Asn Ser Leu Thr Gly Cys Lys
                 230                 235                 240

 Ser Trp Lys Pro Pro Arg Arg Ser Arg Ser Glu Thr Asn Pro Gly
                 245                 250                 255

 Ser Met Glu Gly Thr Gln Thr Leu Lys Arg Asn Asn Asp Val Leu
                 260                 265                 270

 Gln Pro Gln Ala Lys Gly Phe Arg Ser Asp Thr Gly Thr Pro Glu
                 275                 280                 285

 Pro Leu Asp Pro Gln Gly Ser Leu Ser Leu Ser Gln Arg Thr Ser
                 290                 295                 300

 Gln Leu Asp Pro Pro Ala Leu Gln Ala Pro Arg Pro Leu Pro Gln
                 305                 310                 315

 Leu Leu Asp Asp Pro His Glu Val Glu Lys Ser Gly Leu Leu Asn
                 320                 325                 330

 Met Thr Lys Ile Ala Gln Gly Gly Arg Lys Leu Arg Lys Asn Trp
                 335                 340                 345

 Gly Pro Ser Trp Val Val Leu Thr Gly Asn Ser Leu Val Phe Tyr
                 350                 355                 360

 Arg Glu Pro Pro Pro Thr Ala Pro Ser Ser Gly Trp Gly Pro Ala
                 365                 370                 375

 Gly Ser Arg Pro Glu Ser Ser Val Asp Leu Arg Gly Ala Ala Leu
                 380                 385                 390

 Ala His Gly Arg His Leu Ser Ser Arg Arg Asn Val Leu His Ile
                 395                 400                 405

 Arg Thr Ile Pro Gly His Glu Phe Leu Leu Gln Ser Asp His Glu
                 410                 415                 420

 Thr Glu Leu Arg Ala Trp His Arg Ala Leu Arg Thr Val Ile Glu
                 425                 430                 435

 Arg Leu Val Arg Trp Val Glu Ala Arg Arg Glu Ala Pro Thr Gly
                 440                 445                 450

 Arg Asp Gln Gly Ser Gly Asp Arg Glu Asn Pro Leu Glu Leu Arg
                 455                 460                 465

 Leu Ser Gly Ser Gly Pro Ala Glu Leu Ser Ala Gly Glu Asp Glu
                 470                 475                 480

 Glu Glu Glu Ser Glu Leu Val Ser Lys Pro Leu Leu Arg Leu Ser
                 485                 490                 495

 Ser Arg Arg Ser Ser Ile Arg Gly Pro Glu Gly Thr Glu Gln Asn
                 500                 505                 510

 Arg Val Arg Asn Lys Leu Lys Arg Leu Ile Ala Lys Arg Pro Pro
                 515                 520                 525

 Leu Gln Ser Leu Gln Glu Arg Gly Leu Leu Arg Asp Gln Val Phe
                 530                 535                 540

 Gly Cys Gln Leu Glu Ser Leu Cys Gln Arg Glu Gly Asp Thr Val
                 545                 550                 555

 Pro Ser Phe Leu Arg Leu Cys Ile Ala Ala Val Asp Lys Arg Gly
                 560                 565                 570

 Leu Asp Val Asp Gly Ile Tyr Arg Val Ser Gly Asn Leu Ala Val
                 575                 580                 585

 Val Gln Lys Leu Arg Phe Leu Val Asp Arg Glu Arg Ala Val Thr
                 590                 595                 600

 Ser Asp Gly Arg Tyr Val Phe Pro Glu Gln Pro Gly Gln Glu Gly
                 605                 610                 615

 Arg Leu Asp Leu Asp Ser Thr Glu Trp Asp Asp Ile His Val Val
                 620                 625                 630

 Thr Gly Ala Leu Lys Leu Phe Leu Arg Glu Leu Pro Gln Pro Leu
                 635                 640                 645

 Val Pro Pro Leu Leu Leu Pro His Phe Arg Ala Ala Leu Ala Leu
                 650                 655                 660

 Ser Glu Ser Glu Gln Cys Leu Ser Gln Ile Gln Glu Leu Ile Gly
                 665                 670                 675

 Ser Met Pro Lys Pro Asn His Asp Thr Leu Arg Tyr Leu Leu Glu
                 680                 685                 690

 His Leu Cys Arg Val Ile Ala His Ser Asp Lys Asn Arg Met Thr
                 695                 700                 705

 Pro His Asn Leu Gly Ile Val Phe Gly Pro Thr Leu Phe Arg Pro
                 710                 715                 720

 Glu Gln Glu Thr Ser Asp Pro Ala Ala His Ala Leu Tyr Pro Gly
                 725                 730                 735

 Gln Leu Val Gln Leu Met Leu Thr Asn Phe Thr Ser Leu Phe Pro
                 740                 745                 750

<210> 4442
<211> 568
<212> DNA
<213> Homo sapien

<400> 4442
 cccacgcgtc cgccgggcgc gttccgttgg cggcggattc gaacgttcgg 50

 actgaggttt ttctgcctga agaagcgtca tacggaccgg attgttttcg 100

 ctggcccagt gtccccggag cttgtgtgcg atacagagag cacctcggaa 150

 gctgaggcag ctggtacttg acagagagga tggcgctgtc gaccatagtc 200

 tcccagagga agcagataaa gcggaaggct ccccgtggct ttctaaagcg 250

 agtcttcaag cgaaagaagc ctcaacttcg tctggagaaa agtggtgact 300

 tattggtcca tctgaactgt ttactgtttg ttcatcgatt agcagaagag 350

 tccaggacaa acgcttgtgc gagtaaatgt agagtcatta acaaggagca 400

 tgtactggcc gcagcaaagg taattctaaa gaagagcaga ggttagaagt 450

 caaagaacat attcttgaaa gttatgatgc attcttttgg gtggtaacag 500

 atcataaaga cattttttac acatcagtta atatgggatt attaaatatt 550

 ggctataagt gaaaaaaa 568

<210> 4443
<211> 88
<212> PRT
<213> Homo sapien

<400> 4443
 Met Ala Leu Ser Thr Ile Val Ser Gln Arg Lys Gln Ile Lys Arg
   1               5                  10                  15

 Lys Ala Pro Arg Gly Phe Leu Lys Arg Val Phe Lys Arg Lys Lys
                  20                  25                  30

 Pro Gln Leu Arg Leu Glu Lys Ser Gly Asp Leu Leu Val His Leu
                  35                  40                  45

 Asn Cys Leu Leu Phe Val His Arg Leu Ala Glu Glu Ser Arg Thr
                  50                  55                  60

 Asn Ala Cys Ala Ser Lys Cys Arg Val Ile Asn Lys Glu His Val
                  65                  70                  75

 Leu Ala Ala Ala Lys Val Ile Leu Lys Lys Ser Arg Gly
                  80                  85

<210> 4444
<211> 481
<212> DNA
<213> Homo sapien

<400> 4444
 ttttaacttt gcaacaggtt tttatttttg ctttatatct attacagtgt 50

 ttgaaaccta aagaaataca ttttctcttc aaatttggat gtgtatataa 100

 ataacatttg tctggactca gcacactcaa tgccatgttt tcttcgccta 150

 tgtctgctct gaaatcaagc tgtgtctgtc tacccagggg ccctgagaac 200

 atggaaaata gagtttattg ttattagaaa aataaaagca aatgaatttg 250

 caaagaaaaa ccagtgagaa ggattagatt catcttccaa gggtccatag 300

 ctggtaaccc aagccattct cgggggatat ccagtctctt gagtggctgg 350

 gactccatta cccactttcc ttctttaata ggtcaaaggc aattcccaca 400

 aaagctggct aaaaaagccg acacccaact ccagagtctg agggttcatg 450

 aagatgtgga cttttttttt tgagacaaga g 481

<210> 4445
<211> 2349
<212> DNA
<213> Homo sapien

<400> 4445
 ccacgcgtcc gctgtaaacc agaaaaatgt tggttatcta gaaaacttga 50

 gagagcatgt agattaactt ttctctttgg agttctaaaa cattaactgg 100

 aaagattaga taatatacta aatgtataca gaagtataca gactatacaa 150

 agactgaaac aagtcccttt tgcactacaa ctctataaca ttaccgcaga 200

 aattttggtt ctatgtagca tggacctcct aaggaattct gtttctttta 250

 gcattgagat ccctggtgct ctttttttac ctcagaattg gtacaatcat 300

 tattaaacgt taatttattt caaacttttt aattgaaaaa aggaaaggga 350

 aacttaattg gggataaatt caggcatcat attattatga tagagtctcc 400

 tgagtggttc gtctataggt aatgaactca ttggtgttat ttcttggaca 450

 tcttggcctt ttaatcaaag actgtgtgct gctatttgct atgagcaagg 500

 tttctcaaaa gcaaaaggtg cttggaccat ttggatcacc tgagttagaa 550

 tctctaggta tagggcccaa gtatctgcat tttcacaggt ttcttgtagg 600

 tgactttctg caagctaaag tatgagaacc attggcttgg atgtagttct 650

 aaacttttag gtctgtaaat cttgaaatct tgaactgaag gtcaactatt 700

 ggcttttttt tttttttaat ggtccatcat gtcagcaggt gcaaatcact 750

 tttccccttt gcatgatctg aggcacctcc tcagttgttt cactgccaac 800

 tcttatttca gaacctgttt acaaacaagc cttccagttg gtgaatggtt 850

 agccattgga gctcctaccc tgtacatcag cacatcttct ggtttacaag 900

 ttgggtaaca atgaaagctg gagatgctaa atggaaatcc agcattgcat 950

 acccttagac ctgatcacat accagtaaaa gccttaattt agatgttagt 1000

 tgtatgtgtt ggacagatcc ttgcaaaagt gtgtctgtct attagttgta 1050

 aatttgaaaa ttataaatct ctgaatctgc tactatccaa gtttcatccc 1100

 ttttgaagat gaggcatgag cctattaaaa tatttataat catttttcgt 1150

 cccctactgc aagactttta gattcttaca aatgattact acaggaatag 1200

 tggccactta atgtcagtta ctccggtgga agaatttatc tagttttttt 1250

 tcttttcttt tttggaagga tggtgtgaaa aatagcaaga ttagagaatg 1300

 agttgtatag ttttttctat cacatttcat ctaaaatgat ttgaaggact 1350

 tttgaagatt tttaccaaca tccttaaatc aactccaggt tggatgaaca 1400

 actgatttaa aacaaactaa gagaacatta actagatgtg ggctttttaa 1450

 aatatatagg tattgcattt cctaccttgt tatttattcc actttgaata 1500

 ctttagaggg cttaactttc aactctttaa ggtagtaatg gatagtttta 1550

 tacttgttct cacaaaattg ttatggtcag tttatatcat tgctccatgc 1600

 attgattata aaaattcagt attaattttt tctgatctta taagctttat 1650

 aggagttttc ttttctctta taaagtgttt caccttatgt aaaacaaatg 1700

 cctgcttgca tattggaaga tgttgaaatt agttttagac aaaagtggtc 1750

 catcaattca gacactctgc ttggatgcct tacccttttc attagtgcat 1800

 tctttgcttc tgaaacttgg cagaaactcg ttagccagtc cactgccttt 1850

 ctgacaatgt gtggagtcac gtatgcttgg tatatgcctt tactactttt 1900

 aaagttctac agtttattac ttgcccaagt gttactaaat ccttttctta 1950

 tgtgtactgg atggagaaaa aattatagcc agcactttga gaggaaagtt 2000

 ttcagaaaca atattaactg gcactactaa ctgaaggcca caggagatgc 2050

 tatcaatgtt atttgtaatc tgaagattga acaaggctgt gaggctcatt 2100

 tcaaactatt ttgaggtgtt aaaatatata tatgctgttt ctcagctgtt 2150

 ccactcaaac cgtgttagga ctctcaaagg taaaatgtca caggggcttt 2200

 tcagttgtta cagagctcag cagctgtggt tgcccctgtt ctacaccaat 2250

 ttcagttcaa taaaaatgtt aacgggcaaa aaaaatctat gtcgggtgcg 2300

 gagaaagagg taatgaaatg gcaggaattc gatatcagct tatcatacc 2349

<210> 4446
<211> 31
<212> PRT
<213> Homo sapien

<400> 4446
 Pro Arg Val Arg Cys Lys Pro Glu Lys Cys Trp Leu Ser Arg Lys
   1               5                  10                  15

 Leu Glu Arg Ala Cys Arg Leu Thr Phe Leu Phe Gly Val Leu Lys
                  20                  25                  30

 His


<210> 4447
<211> 3591
<212> DNA
<213> Homo sapien

<400> 4447
 ccgtaaagcg gtggagaatc tcaagcatgt gcatttaatt gaggaatagc 50

 agaagggcta aagcaaccaa gaaaagaagt gtgggtattt ttgttaagta 100

 aaacagccca agtgcttctg gaggtgggtt tctaccaaga tagaggaaaa 150

 gggctgaatt ccctctaagt gggacagccg agctcaggat gtgcttccca 200

 gcttcactgg ttaatttgac ctgaacctat ttaaagatcc cttctgcccc 250

 tgaagaccta tccgcactca aattctaaca tgaagaaatc tactcgaatg 300

 catcctttac tttgaatgag ctctattcgg ttgcatgtta tatgtgattt 350

 ccttcctccc aactgtttcc actgagcgca cccagtctcc cctagtcttc 400

 ctctgtgggt gtgatttttg tgatttttac aaacaaaacc cttgaagttc 450

 ttggcagatg tgtttgtttc tgtttgcatg tactgcagat accccaggac 500

 aagcggggga ttcatttttc agccattcag ttgtttcctc aataatccgc 550

 agcaaagtga aaatattctt agcactcaga ctgtacttag agtgttttct 600

 cagtccagtc tgtacagtct gtaggcagaa ggcctcagaa gaaagtcatg 650

 gccactcagt gcccactgtg ggctttgtaa gtcctggctc tcccgtcaag 700

 gttacccaga ggtaaaagct tcctgggagt ggggccaggt gtgtttggca 750

 ctccagatag aaggcaaaat gctcagattc gggcctgtgc acttgtatgc 800

 aacctgtcgg tcgataccta gcatttattt ttccctgaca atgaacgacc 850

 tttccctcac ccaccctaag ctcaaagagt ttagcaaaat tctcttttaa 900

 ataaacagaa tgccagtaag aggttgaccc ctaccatgga acttctggga 950

 tgctaaatac ttcctcatga acaaaataag ttccttatta taagttcctt 1000

 atactagcag cttcacctaa agaattttct ctccagcaat attgacttca 1050

 ctggggaaaa gccaagagtg tgtggtgagt gatttgttct cactcgacct 1100

 ggctaggact ggctaggagc tgttttttgt acatgaggga atttgggctt 1150

 tcctcagtta tctgaatgtt ttacccaagt gccttcctgc tattgtagca 1200

 aagtagctca gcttccttgt ccacagggtg aaaaaggact aatgcatttt 1250

 ccatcagttt tctaactatg ttagcaaaaa cggcctcctg gtagctcaac 1300

 ctcctgtacg cgtgtgtgtg tgtaatacac acacaaataa acccctctgt 1350

 ttttctaaga catcttagct ggatattata ggaagcactt tcataaacaa 1400

 ctgtaacaaa tcgcaaagga aagagaaaca aaagcattag atttgagaca 1450

 taaacaggca agagaaagtg tattaggaac tgacagctat caaggaagtt 1500

 ttgtcagtta caaatgctag gaggaaattt tgccaagaag gatggctcat 1550

 gaaatatttc cagtacggga agaggcaata agatcctcta agagaatgag 1600

 aaagtagggg tgtctaaatg gtaaagatgg gtgtgttgca cgtgtgttag 1650

 aaggatctca gttgagtgaa ggtttgcact gctacatcta agttaatgta 1700

 aatatgtagc actctgacag gtctaccgtg ttgctgaatg tagtatattt 1750

 ccaaagtttg caagtcttcc tgtattgtac aaagatgctg ctgcttgata 1800

 atatgtatag caatccagat tagtatgtta ttaaatttta ttttcttacc 1850

 tgtattttta tgctttttac ctgtcctcaa aatattacac ccctgttgga 1900

 attagattta tatttataaa tggtcagaaa tctttttaag tgtctctttt 1950

 tacacatagg ttgatttttt tttcttaaga gaaatgatgt attcttgaaa 2000

 catttgttac tcattccagg aaacaaaaac ccatataata aaacccccac 2050

 tcagagcctg ttagtcacct ctctagaaga tggcatctca ggagaaggaa 2100

 tggctttgtg gaagaaggaa tcaccttttt cttgctcaag aattatgctg 2150

 acttcagccc tgagcctgga tctggtcact gagaatcatc aagtgtctag 2200

 atcctccccc caaaataact aatttagtag gtgattttga ttttaaaaaa 2250

 ttgacaccaa aaccctgcct gcattgtaat ggaattcgaa aagaattcat 2300

 gttcacagaa ctcaacgttc aggctaatat ttacagaagg gaccaaatct 2350

 aaatcctggt agataactcc tgtatgcttt atccaaagga cacccacagt 2400

 tttccagcat agatataacc aaggatgaat tgattccttc aaagaactgg 2450

 gaggcacgga tattgcattt tttgtttaca tccagtagcc aagacgcctc 2500

 agtgagccag tcttgggcag aggctgtcac atttaggcag attggaagtt 2550

 ggtatgttct aattctcact ctggactaca gtgaggctga atttatcatg 2600

 tcaaaaaaaa aaaaaaaaaa aaagaccttt ccaagtgctt tctattgctc 2650

 agaattgaaa gaatgttttc atttcaagtt tacaagaggc atggatggag 2700

 ttgtgacgtt cttgacaagc tgggctaacc tttcccgaac ttgtttcccg 2750

 gaggcaaggt gctcggtgac ccagcgcatc ttaaccttgg gtctcctagg 2800

 ctcgaggcta gggcattacg tttcgtggaa ccaaagcagc caattgcata 2850

 gcaagtattt tcctgcattc caattaaatg cttaagaaaa agcagcatcc 2900

 tataaaattg tgatcataaa catccatttc cctcagcttt tgtgagtgcc 2950

 ttgacttaca gccaacatca ctgtttaact cagtctgttt aaaaacaaac 3000

 ttttctggtg gttgataaca gagagttgct ccctgagcca tcagggtcct 3050

 gggagctgga agtgaaaggg ttattaacat tctaccttta tgcagctgtt 3100

 ggctgaccag aataaactcc ctgctgagtt caagctttga atggaatgga 3150

 tgcaaatgat gttgtttcca ttagagcagg tgctcacagc attctgattg 3200

 gcctgagcag accgaggcta tggctgttgg gacaagctta gcatcctgga 3250

 catcttgtca aagaacctca ctcacccctc ttggcctcta cagccctcag 3300

 aggagagaaa accaattctc caacaaacag gtctctccaa catggtggtg 3350

 ctggcaggct taggtttaga aaatcctgac tgttaaaggc gtttgaatac 3400

 atcacattcc tatgcaaatg tttttaatct ccagtttaat gtagtttatt 3450

 tttcctatat gtaaagtatt tttatacggc ttgtatcatg atagtttagc 3500

 aataaaacag ttggccgcaa aaaaaatcta tgtcgggtgc ggagaaagag 3550

 gtaatgaaat ggcaggaatt cgatagcagc ttatcgatac c 3591

<210> 4448
<211> 12
<212> PRT
<213> Homo sapien

<400> 4448
 Met Lys Trp Gln Glu Phe Asp Ser Ser Leu Ser Ile
   1               5                  10

<210> 4449
<211> 723
<212> DNA
<213> Homo sapien

<400> 4449
 gcctcaagcc gacgcagcgg cctactctcg cactgcagac ggggaaactg 50

 aggcctgagg cggccggggt ggggcagacc tcccggcgag cccgagcccc 100

 cgcccccggc tagccccgcc ctggcccgta agaagcaccc ggggcgcgag 150

 gcgaaggcgc acagcgcggg gccaggctgg gtccagcagc gcgatggcag 200

 ctcagcggct gggcaagcgc gtgctgagca agctgcagtc tccatcgcgg 250

 gcccgcgggc cagggggcag tcccgggggg ctgcagaagc ggcacgcgcg 300

 cgtcaccgtc aagtatgacc ggcgggagct gcagcggcgg ctggacgtgg 350

 agaagtggat cgacgggcgc ctggaggagc tgtaccgcgg catggaggca 400

 gacatgcccg atgagatcaa cattgatgaa ttgttggagt tagagagtga 450

 agaggagaga agccggaaaa tccagggact cctgaagtca tgtgggaaac 500

 ctgtcgagga cttcatccag gagctgctgg caaagcttca aggcctccac 550

 aggcagcccg gcctccgcca gccaagcccc tcccacgacg gcagcctcag 600

 ccccctccag gaccgggccc ggactgctca cccctgaccc tcttgcactc 650

 tccctgcccc ccggacgccg cccagcttgc ttgtgtataa gttgtattta 700

 atggttctgt aacaataaaa aaa 723

<210> 4450
<211> 147
<212> PRT
<213> Homo sapien

<400> 4450
 Met Ala Ala Gln Arg Leu Gly Lys Arg Val Leu Ser Lys Leu Gln
   1               5                  10                  15

 Ser Pro Ser Arg Ala Arg Gly Pro Gly Gly Ser Pro Gly Gly Leu
                  20                  25                  30

 Gln Lys Arg His Ala Arg Val Thr Val Lys Tyr Asp Arg Arg Glu
                  35                  40                  45

 Leu Gln Arg Arg Leu Asp Val Glu Lys Trp Ile Asp Gly Arg Leu
                  50                  55                  60

 Glu Glu Leu Tyr Arg Gly Met Glu Ala Asp Met Pro Asp Glu Ile
                  65                  70                  75

 Asn Ile Asp Glu Leu Leu Glu Leu Glu Ser Glu Glu Glu Arg Ser
                  80                  85                  90

 Arg Lys Ile Gln Gly Leu Leu Lys Ser Cys Gly Lys Pro Val Glu
                  95                 100                 105

 Asp Phe Ile Gln Glu Leu Leu Ala Lys Leu Gln Gly Leu His Arg
                 110                 115                 120

 Gln Pro Gly Leu Arg Gln Pro Ser Pro Ser His Asp Gly Ser Leu
                 125                 130                 135

 Ser Pro Leu Gln Asp Arg Ala Arg Thr Ala His Pro
                 140                 145

<210> 4451
<211> 5486
<212> DNA
<213> Homo sapien

<400> 4451
 cgcggcgtga gcgccccggg aagatggagc agtcgccgtc cacgccaccg 50

 ccgccgcccg gggctccccc gtccctgcgg ggccagcagc agctccagcc 100

 accagtgccc ggtctcccgg cgcgagaggc ccgggagccg ccggccagga 150

 cgcccccgag ggtgtagacc gcgcccctgg agagagtgat aatcttcaaa 200

 atgaagactt tggaaaattt taggttctct ataggaacta caaaaatgga 250

 aggaaagaac attttcaaaa ggaaattatt ttgaaagtat gtttacaaca 300

 aactgatact attgacagtt ttttttttta aataataaaa cactttaaga 350

 agattgtatt tatggtaaaa ggaaactgga ctaacaatga ggccaaagac 400

 ttttcctgcc acgacttatt ctggaaatag ccggcagcga ctgcaagaga 450

 ttcgtgaggg gttaaaacag ccatccaagt cttcggttca ggggctaccc 500

 gcaggaccaa acagtgacac ttccctggat gccaaagtcc tggggagcaa 550

 agatgccacc aggcagcagc agcagatgag agccacccca aagttcggac 600

 cttatcagaa agccttgagg gaaatcagat attccttgtt gccttttgct 650

 aatgaatcgg gcacctctgc agctgcagaa gtgaaccggc aaatgctgca 700

 ggaactggtg aacgcaggat gcgaccagga gatggctggc cgagctctca 750

 agcagactgg cagcaggagc atcgaggccg ccctggagta catcagcaag 800

 atgggctacc tggacccgag gaatgagcag attgtgcggg tcattaagca 850

 gacctcccca ggaaaggggc tcatgccaac cccagtgacg cggaggccca 900

 gcttcgaagg aaccggcgat tcgtttgcgt cctaccacca gctgagcggt 950

 accccctacg agggcccaag cttcggcgct gacggcccca cggcgctgga 1000

 ggagatgccg cggccgtacg tggactacct tttccccgga gtcggccccc 1050

 acgggcccgg ccaccagcac cagcacccac ccaagggcta cggtgccagc 1100

 gtagaggcag caggggcaca cttcccgctg cagggcgcgc actacgggcg 1150

 gccgcacctg ctggtgcctg gggaacccct gggctacgga gtgcagcgca 1200

 gcccctcctt ccagagcaag acgccgccgg agaccggggg ttacgccagc 1250

 ctgcccacga agggccaggg aggaccgcca ggcgccggcc tcgctttccc 1300

 accccctgcc gccgggctct acgtgccgca cccacaccac aagcaggccg 1350

 gtcccgtggc ccaccagctg catgtgctgg gctcccgcag ccaggtgttc 1400

 gccagcgaca gccccccgca gagcctgctc actccctcgc ggaacagcct 1450

 caacgtggac ctgtatgaat tgagcagcac ctccgtccag cagtggccgg 1500

 ctgccaccct ggcccgccgg gactccctgc agaagccggg cctggaggcg 1550

 ccgccgcgcg cgcacgtggc cttccggcct gactgcccag tgcccagcag 1600

 gaccaactcc ttcaacagcc accagccgcg gcccggtccg cctggcaagg 1650

 ccgagccctc cctgcccgcc cccaacaccg tgacggctgt cacggccgcg 1700

 cacatcttgc acccggtgaa gagcgtgcgt gtgctgaggc cggagccgca 1750

 gacggctgtg gggccctcgc accccgcctg ggtgcccgcg cctgccccgg 1800

 cccccgcccc cgcccccgcc ccggctgcgg agggcttgga cgccaaggag 1850

 gagcatgccc tggcgctggg cggcgcaggc gccttcccgc tggacgtgga 1900

 gtacggaggc ccagaccgga ggtgcccgcc tccgccctac ccgaagcacc 1950

 tgctgctgcg cagcaagtcg gagcagtacg acctggacag cctgtgcgca 2000

 ggcatggagc agagcctccg tgcgggcccc aacgagcccg agggcggcga 2050

 caagagccgc aaaagcgcca agggggacaa aggcggaaag gataaaaagc 2100

 agattcagac ctctcccgtt cccgtccgca aaaacagcag agacgaagag 2150

 aagagagagt cacgcatcaa gagctactcg ccatacgcct ttaagttctt 2200

 catggagcag cacgtggaga atgtcatcaa aacctaccag cagaaggtta 2250

 accggaggct gcagctggag caagaaatgg ccaaagctgg actctgtgaa 2300

 gctgagcagg agcagatgcg gaagatcctc taccagaaag agtctaatta 2350

 caacaggtta aagagggcca agatggacaa gtctatgttt gtcaagatca 2400

 aaaccctggg gatcggtgcc tttggagaag tgtgccttgc ttgtaaggtg 2450

 gacactcacg ccctgtacgc catgaagacc ctaaggaaaa aggatgtcct 2500

 gaaccggaat caggtggccc acgtcaaggc cgagagggac atcctggccg 2550

 aggcagacaa tgagtgggtg gtcaaactct actactcctt ccaagacaaa 2600

 gacagcctgt actttgtgat ggactacatc cctggtgggg acatgatgag 2650

 cctgctgatc cggatggagg tcttccctga gcacctggcc cggttctaca 2700

 tcgcagagct gactttggcc attgagagtg tccacaagat gggcttcatc 2750

 caccgagaca tcaagcctga taacattttg atagatctgg atggtcacat 2800

 taaactcaca gatttcggcc tctgcactgg gttcaggtgg actcacaatt 2850

 ccaaatatta ccagaaaggg agccatgtca gacaggacag catggagccc 2900

 agcgacctct gggatgatgt gtctaactgt cggtgtgggg acaggctgaa 2950

 gaccctagag cagagggcgc ggaagcagca ccagaggtgc ctggcacatt 3000

 cactggtggg gactccaaac tacatcgcac ccgaggtgct cctccgcaaa 3050

 gggtacactc aactctgtga ctggtggagt gttggagtga ttctcttcga 3100

 gatgctggtg gggcagccgc cctttttggc acctactccc acagaaaccc 3150

 agctgaaggt gatcaactgg gagaacacgc tccacattcc agcccaggtg 3200

 aagctgagcc ctgaggccag ggacctcatc accaagctgt gctgctccgc 3250

 agaccaccgc ctggggcgga atggggccga tgacctgaag gcccacccct 3300

 tcttcagcgc cattgacttc tccagtgaca tccggaagca gccagccccc 3350

 tacgttccca ccatcagcca ccccatggac acctcgaatt tcgaccccgt 3400

 agatgaagaa agcccttgga acgatgccag cgaaggtagc accaaggcct 3450

 gggacacact cacctcgccc aataacaagc atcctgagca cgcattttac 3500

 gaattcacct tccgaaggtt ctttgatgac aatggctacc cctttcgatg 3550

 cccaaagcct tcaggagcag aagcttcaca ggctgagagc tcagatttag 3600

 aaagctctga tctggtggat cagactgaag gctgccagcc tgtgtacgtg 3650

 tagatggggg ccaggcaccc ccaccactcg ctgcctccca ggtcagggtc 3700

 ccggagccgg tgccctcaca ggccaatagg gaagccgagg gctgttttgt 3750

 tttaaattag tccgtcgatt acttcacttg aaattctgct cttcaccaag 3800

 aaaacccaaa caggacactt ttgaaaacag gactcagcat cgctttcaat 3850

 aggcttttca ggaccttcac tgcattaaaa caatattttt gaaaatttag 3900

 tacagtttag aaagagcact tattttgttt atatccattt tttcttacta 3950

 aattataggg attaactttg acaaatcatg ctgctgttat tttctacatt 4000

 tgtattttat ccatagcact tattcacatt taggaaaaga cataaaaact 4050

 gaagaacatt gatgagaaat ctctgtgcaa taatgtaaaa aaaaaaaaga 4100

 taacactctg ctcaatgtca cggagaccat tttatccaca caatggtttt 4150

 tgttttttat tttttcccat gtttcaaaat tgtgatataa tgatataatg 4200

 ttaaaagctg ctttttttgg ctttttgcat atctagtata ataggaagtg 4250

 tgagcaaggt gatgatgtgg ctgtgatttc cgacgtctgg tgtgtggaga 4300

 gtactgcatg agcagagttc ttctattata aaattaccat atcttgccat 4350

 tcacagcagg tcctgtgaat acgtttttac tgagtgtctt taaatgaggt 4400

 gttctagaca gtgtgctgat aatgtattgt gcgggtgacc tcttcgctat 4450

 gattgtatct cttactgttt tgttaaagaa atgcagatgt gtaactgaga 4500

 agtgatttgt gtgtgtgtct tggttgtgat tggattcttt gggggggggg 4550

 gaactgaaac atttgtcata tactgaactt atatacatca aaagggatta 4600

 atacagcgat gccaaaaagt ttaatcacgg acacacgtcc gtttctgtag 4650

 tccgtatgct ctttcattct tggtagagct ggtatgtgga atgccatacc 4700

 tctgacccta ctacttacct ttttactgac agactgccca cactgaaagc 4750

 ttcagtgaat gttcttagtc ctgttttctt ctgttactgt caggaaactg 4800

 agtgatctaa tggttctctc actttttttt tgttctttta gtgtactttg 4850

 aagtatcaaa tcttaacttg gtttaaacaa tacatattcc taacctttgt 4900

 aaaaaagcaa agattcttca aaatgacatt gaaataaaaa gtaagccata 4950

 cgtattttct tagaagtata gatgtatgtg cgtgtataca cacacacaca 5000

 cacacacaga gataaacaca atattcctta tttcaaatta gtatgattcc 5050

 tatttaaagt gatttatatt tgagtaaaaa gttcaattct tttttgcttt 5100

 ttaaaaaatc tgatgcttca taattttcat tatattattc cacatatttt 5150

 tccttgaagt tcttagcata atgtatccat tacttagtat atatctaggc 5200

 aacaacactt agaagtttat cagtgtttaa actaaaaaaa taaagattcc 5250

 tgtgtactgg tttacatttg tgtgagtggc atactcaagt ctgctgtgcc 5300

 tgtcgtcgtg actgtcagta ttctcgctat tttatagtcg tgccatgttg 5350

 ttactcacag cgctctgaca tactttcatg tggtaggttc tttctcagga 5400

 actcagttta actattattt attgatatat cattaccttt gaaaagcttc 5450

 tactggcaca atttattatt aaaattttga atccag 5486

<210> 4452
<211> 1088
<212> PRT
<213> Homo sapien

<400> 4452
 Met Arg Pro Lys Thr Phe Pro Ala Thr Thr Tyr Ser Gly Asn Ser
   1               5                  10                  15

 Arg Gln Arg Leu Gln Glu Ile Arg Glu Gly Leu Lys Gln Pro Ser
                  20                  25                  30

 Lys Ser Ser Val Gln Gly Leu Pro Ala Gly Pro Asn Ser Asp Thr
                  35                  40                  45

 Ser Leu Asp Ala Lys Val Leu Gly Ser Lys Asp Ala Thr Arg Gln
                  50                  55                  60

 Gln Gln Gln Met Arg Ala Thr Pro Lys Phe Gly Pro Tyr Gln Lys
                  65                  70                  75

 Ala Leu Arg Glu Ile Arg Tyr Ser Leu Leu Pro Phe Ala Asn Glu
                  80                  85                  90

 Ser Gly Thr Ser Ala Ala Ala Glu Val Asn Arg Gln Met Leu Gln
                  95                 100                 105

 Glu Leu Val Asn Ala Gly Cys Asp Gln Glu Met Ala Gly Arg Ala
                 110                 115                 120

 Leu Lys Gln Thr Gly Ser Arg Ser Ile Glu Ala Ala Leu Glu Tyr
                 125                 130                 135

 Ile Ser Lys Met Gly Tyr Leu Asp Pro Arg Asn Glu Gln Ile Val
                 140                 145                 150

 Arg Val Ile Lys Gln Thr Ser Pro Gly Lys Gly Leu Met Pro Thr
                 155                 160                 165

 Pro Val Thr Arg Arg Pro Ser Phe Glu Gly Thr Gly Asp Ser Phe
                 170                 175                 180

 Ala Ser Tyr His Gln Leu Ser Gly Thr Pro Tyr Glu Gly Pro Ser
                 185                 190                 195

 Phe Gly Ala Asp Gly Pro Thr Ala Leu Glu Glu Met Pro Arg Pro
                 200                 205                 210

 Tyr Val Asp Tyr Leu Phe Pro Gly Val Gly Pro His Gly Pro Gly
                 215                 220                 225

 His Gln His Gln His Pro Pro Lys Gly Tyr Gly Ala Ser Val Glu
                 230                 235                 240

 Ala Ala Gly Ala His Phe Pro Leu Gln Gly Ala His Tyr Gly Arg
                 245                 250                 255

 Pro His Leu Leu Val Pro Gly Glu Pro Leu Gly Tyr Gly Val Gln
                 260                 265                 270

 Arg Ser Pro Ser Phe Gln Ser Lys Thr Pro Pro Glu Thr Gly Gly
                 275                 280                 285

 Tyr Ala Ser Leu Pro Thr Lys Gly Gln Gly Gly Pro Pro Gly Ala
                 290                 295                 300

 Gly Leu Ala Phe Pro Pro Pro Ala Ala Gly Leu Tyr Val Pro His
                 305                 310                 315

 Pro His His Lys Gln Ala Gly Pro Val Ala His Gln Leu His Val
                 320                 325                 330

 Leu Gly Ser Arg Ser Gln Val Phe Ala Ser Asp Ser Pro Pro Gln
                 335                 340                 345

 Ser Leu Leu Thr Pro Ser Arg Asn Ser Leu Asn Val Asp Leu Tyr
                 350                 355                 360

 Glu Leu Ser Ser Thr Ser Val Gln Gln Trp Pro Ala Ala Thr Leu
                 365                 370                 375

 Ala Arg Arg Asp Ser Leu Gln Lys Pro Gly Leu Glu Ala Pro Pro
                 380                 385                 390

 Arg Ala His Val Ala Phe Arg Pro Asp Cys Pro Val Pro Ser Arg
                 395                 400                 405

 Thr Asn Ser Phe Asn Ser His Gln Pro Arg Pro Gly Pro Pro Gly
                 410                 415                 420

 Lys Ala Glu Pro Ser Leu Pro Ala Pro Asn Thr Val Thr Ala Val
                 425                 430                 435

 Thr Ala Ala His Ile Leu His Pro Val Lys Ser Val Arg Val Leu
                 440                 445                 450

 Arg Pro Glu Pro Gln Thr Ala Val Gly Pro Ser His Pro Ala Trp
                 455                 460                 465

 Val Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala
                 470                 475                 480

 Ala Glu Gly Leu Asp Ala Lys Glu Glu His Ala Leu Ala Leu Gly
                 485                 490                 495

 Gly Ala Gly Ala Phe Pro Leu Asp Val Glu Tyr Gly Gly Pro Asp
                 500                 505                 510

 Arg Arg Cys Pro Pro Pro Pro Tyr Pro Lys His Leu Leu Leu Arg
                 515                 520                 525

 Ser Lys Ser Glu Gln Tyr Asp Leu Asp Ser Leu Cys Ala Gly Met
                 530                 535                 540

 Glu Gln Ser Leu Arg Ala Gly Pro Asn Glu Pro Glu Gly Gly Asp
                 545                 550                 555

 Lys Ser Arg Lys Ser Ala Lys Gly Asp Lys Gly Gly Lys Asp Lys
                 560                 565                 570

 Lys Gln Ile Gln Thr Ser Pro Val Pro Val Arg Lys Asn Ser Arg
                 575                 580                 585

 Asp Glu Glu Lys Arg Glu Ser Arg Ile Lys Ser Tyr Ser Pro Tyr
                 590                 595                 600

 Ala Phe Lys Phe Phe Met Glu Gln His Val Glu Asn Val Ile Lys
                 605                 610                 615

 Thr Tyr Gln Gln Lys Val Asn Arg Arg Leu Gln Leu Glu Gln Glu
                 620                 625                 630

 Met Ala Lys Ala Gly Leu Cys Glu Ala Glu Gln Glu Gln Met Arg
                 635                 640                 645

 Lys Ile Leu Tyr Gln Lys Glu Ser Asn Tyr Asn Arg Leu Lys Arg
                 650                 655                 660

 Ala Lys Met Asp Lys Ser Met Phe Val Lys Ile Lys Thr Leu Gly
                 665                 670                 675

 Ile Gly Ala Phe Gly Glu Val Cys Leu Ala Cys Lys Val Asp Thr
                 680                 685                 690

 His Ala Leu Tyr Ala Met Lys Thr Leu Arg Lys Lys Asp Val Leu
                 695                 700                 705

 Asn Arg Asn Gln Val Ala His Val Lys Ala Glu Arg Asp Ile Leu
                 710                 715                 720

 Ala Glu Ala Asp Asn Glu Trp Val Val Lys Leu Tyr Tyr Ser Phe
                 725                 730                 735

 Gln Asp Lys Asp Ser Leu Tyr Phe Val Met Asp Tyr Ile Pro Gly
                 740                 745                 750

 Gly Asp Met Met Ser Leu Leu Ile Arg Met Glu Val Phe Pro Glu
                 755                 760                 765

 His Leu Ala Arg Phe Tyr Ile Ala Glu Leu Thr Leu Ala Ile Glu
                 770                 775                 780

 Ser Val His Lys Met Gly Phe Ile His Arg Asp Ile Lys Pro Asp
                 785                 790                 795

 Asn Ile Leu Ile Asp Leu Asp Gly His Ile Lys Leu Thr Asp Phe
                 800                 805                 810

 Gly Leu Cys Thr Gly Phe Arg Trp Thr His Asn Ser Lys Tyr Tyr
                 815                 820                 825

 Gln Lys Gly Ser His Val Arg Gln Asp Ser Met Glu Pro Ser Asp
                 830                 835                 840

 Leu Trp Asp Asp Val Ser Asn Cys Arg Cys Gly Asp Arg Leu Lys
                 845                 850                 855

 Thr Leu Glu Gln Arg Ala Arg Lys Gln His Gln Arg Cys Leu Ala
                 860                 865                 870

 His Ser Leu Val Gly Thr Pro Asn Tyr Ile Ala Pro Glu Val Leu
                 875                 880                 885

 Leu Arg Lys Gly Tyr Thr Gln Leu Cys Asp Trp Trp Ser Val Gly
                 890                 895                 900

 Val Ile Leu Phe Glu Met Leu Val Gly Gln Pro Pro Phe Leu Ala
                 905                 910                 915

 Pro Thr Pro Thr Glu Thr Gln Leu Lys Val Ile Asn Trp Glu Asn
                 920                 925                 930

 Thr Leu His Ile Pro Ala Gln Val Lys Leu Ser Pro Glu Ala Arg
                 935                 940                 945

 Asp Leu Ile Thr Lys Leu Cys Cys Ser Ala Asp His Arg Leu Gly
                 950                 955                 960

 Arg Asn Gly Ala Asp Asp Leu Lys Ala His Pro Phe Phe Ser Ala
                 965                 970                 975

 Ile Asp Phe Ser Ser Asp Ile Arg Lys Gln Pro Ala Pro Tyr Val
                 980                 985                 990

 Pro Thr Ile Ser His Pro Met Asp Thr Ser Asn Phe Asp Pro Val
                 995                1000                1005

 Asp Glu Glu Ser Pro Trp Asn Asp Ala Ser Glu Gly Ser Thr Lys
                1010                1015                1020

 Ala Trp Asp Thr Leu Thr Ser Pro Asn Asn Lys His Pro Glu His
                1025                1030                1035

 Ala Phe Tyr Glu Phe Thr Phe Arg Arg Phe Phe Asp Asp Asn Gly
                1040                1045                1050

 Tyr Pro Phe Arg Cys Pro Lys Pro Ser Gly Ala Glu Ala Ser Gln
                1055                1060                1065

 Ala Glu Ser Ser Asp Leu Glu Ser Ser Asp Leu Val Asp Gln Thr
                1070                1075                1080

 Glu Gly Cys Gln Pro Val Tyr Val
                1085

<210> 4453
<211> 1931
<212> DNA
<213> Homo sapien

<400> 4453
 ggctcgggct ccggctcggg ctcccgcggc gtgggctggg cagcagccgg 50

 gcggcggctc cgcggcgccg ggcaggggcc gtccgcgggt ccgcgccctc 100

 gggcggcggc gtctcctggg tcccggcagc cgtccgcgcg cccgggcgca 150

 ggtttggttt tcctaaacaa atcctttcac agggaccgac ggcacttgat 200

 aatgtgacaa aaaccagcct cttccacccc actgcagtga cttttgccgg 250

 aaagtggagc agtgggcacg gccaaccttg tcgttcatca atgccgcccc 300

 tggcagtatc tgaggatcgg tggcagccat gcctccccct gccccagccg 350

 ctccttcccc cccacgctaa tctgcatggt gtgggcgccc ttgggacccc 400

 cgaggactga ttgtctgacc ttgcttcaca cgcccagtaa ggactccccc 450

 aagatgtcgc tcgagtggct ggtggcctgg agctggtcgc tggatggcct 500

 gagggactgc atcgccaccg gcatccagtc cgtgcgggac tgcgacacca 550

 ccgctgtcat cactgtggcc tgcctcctgg tcctcttcgt gtggtactgt 600

 tatcacgtgg gcagggagca gccccggccc tacgtctccg tcaactccct 650

 catgcaggct gccgatgcca acgggctgca gaatggctac gtgtactgcc 700

 agtcccctga gtgcgtgcgc tgcacccaca acgagggcct caaccagaag 750

 ctgtaccaca acctgcagga gtacgccaag cgctactcct ggtccggcat 800

 gggccgcatc cacaagggca tccgcgagca gggccggtac ctcaacagcc 850

 ggccctccat ccagaagccc gaggtcttct tcctgcccga cctgcccacc 900

 acgccctatt tctcccggga cgcacagaaa catgatgtgg aagtgctgga 950

 acggaacttc cagaccatcc tgtgtgagtt tgagaccctc tacaaagctt 1000

 tctcaaactg cagcctcccg caaggatgga aaatgaacag cacccccagc 1050

 ggggagtggt tcacctttta cttggtcaat cagggggttt gtgttcccag 1100

 gaactgtagg aagtgcccac ggacgtaccg cttgctcgga agccttcgga 1150

 cctgtattgg gaacaatgtt tttgggaacg cgtgcatctc tgtgctgagc 1200

 cctgggactg tgataacgga gcactatgga cccaccaaca tccgcatccg 1250

 atgccattta ggtctgaaaa ctccaaatgg ctgtgagctg gtggtggggg 1300

 gagagcccca gtgctgggca gaagggcgct gccttctctt tgatgactct 1350

 ttcctgcatg ctgcgttcca tgaaggttca gcagaggatg gcccacgggt 1400

 ggttttcatg gtggatttgt ggcatccaaa cgtcgcagcg gccgaacggc 1450

 aggctcttga tttcatcttt gctccgggac gatgagagta tttcccatgc 1500

 tggagtcggc gagaagggcc gaggcggggc ctgggcagac tgtggtccgg 1550

 tccagtccct accggtgttg tttccatgct cagaaacctg cctcagcgga 1600

 aagctcttat ttgggatttt atatcatgtc gggtccctct ttcccttggt 1650

 tattgtaaat ggaaactttt cggcttgtat ttccttagat tttttttttt 1700

 tccttccaat catttgcttc agagactcct ttctggccta acagcgcatt 1750

 cctttgattg gtccttgagt gaccagagac ttagtgccct tgtaagtctg 1800

 tcttctgttg ctacttgttt ttttcagtgc tctgaaatag agtaactaaa 1850

 tggttatttg tctgaatata ataatgtaaa acttaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1931

<210> 4454
<211> 343
<212> PRT
<213> Homo sapien

<400> 4454
 Met Ser Leu Glu Trp Leu Val Ala Trp Ser Trp Ser Leu Asp Gly
   1               5                  10                  15

 Leu Arg Asp Cys Ile Ala Thr Gly Ile Gln Ser Val Arg Asp Cys
                  20                  25                  30

 Asp Thr Thr Ala Val Ile Thr Val Ala Cys Leu Leu Val Leu Phe
                  35                  40                  45

 Val Trp Tyr Cys Tyr His Val Gly Arg Glu Gln Pro Arg Pro Tyr
                  50                  55                  60

 Val Ser Val Asn Ser Leu Met Gln Ala Ala Asp Ala Asn Gly Leu
                  65                  70                  75

 Gln Asn Gly Tyr Val Tyr Cys Gln Ser Pro Glu Cys Val Arg Cys
                  80                  85                  90

 Thr His Asn Glu Gly Leu Asn Gln Lys Leu Tyr His Asn Leu Gln
                  95                 100                 105

 Glu Tyr Ala Lys Arg Tyr Ser Trp Ser Gly Met Gly Arg Ile His
                 110                 115                 120

 Lys Gly Ile Arg Glu Gln Gly Arg Tyr Leu Asn Ser Arg Pro Ser
                 125                 130                 135

 Ile Gln Lys Pro Glu Val Phe Phe Leu Pro Asp Leu Pro Thr Thr
                 140                 145                 150

 Pro Tyr Phe Ser Arg Asp Ala Gln Lys His Asp Val Glu Val Leu
                 155                 160                 165

 Glu Arg Asn Phe Gln Thr Ile Leu Cys Glu Phe Glu Thr Leu Tyr
                 170                 175                 180

 Lys Ala Phe Ser Asn Cys Ser Leu Pro Gln Gly Trp Lys Met Asn
                 185                 190                 195

 Ser Thr Pro Ser Gly Glu Trp Phe Thr Phe Tyr Leu Val Asn Gln
                 200                 205                 210

 Gly Val Cys Val Pro Arg Asn Cys Arg Lys Cys Pro Arg Thr Tyr
                 215                 220                 225

 Arg Leu Leu Gly Ser Leu Arg Thr Cys Ile Gly Asn Asn Val Phe
                 230                 235                 240

 Gly Asn Ala Cys Ile Ser Val Leu Ser Pro Gly Thr Val Ile Thr
                 245                 250                 255

 Glu His Tyr Gly Pro Thr Asn Ile Arg Ile Arg Cys His Leu Gly
                 260                 265                 270

 Leu Lys Thr Pro Asn Gly Cys Glu Leu Val Val Gly Gly Glu Pro
                 275                 280                 285

 Gln Cys Trp Ala Glu Gly Arg Cys Leu Leu Phe Asp Asp Ser Phe
                 290                 295                 300

 Leu His Ala Ala Phe His Glu Gly Ser Ala Glu Asp Gly Pro Arg
                 305                 310                 315

 Val Val Phe Met Val Asp Leu Trp His Pro Asn Val Ala Ala Ala
                 320                 325                 330

 Glu Arg Gln Ala Leu Asp Phe Ile Phe Ala Pro Gly Arg
                 335                 340

<210> 4455
<211> 5277
<212> DNA
<213> Homo sapien

<400> 4455
 gtgggccgcg gcggtggcgg agactgtggc tttaagagcg tgccgggagc 50

 ccgagcccca gccgggccgc gcttcgccgc tgcgcacccc agcggagcca 100

 agccccacgc tggccggaca gggccgcctg tcgccgggct gctgagaact 150

 agccctagac ctctgcgtga gggttcttct gccgaagaca tcaccagtgt 200

 gtggagcctg ccacacccac ccgctgccaa accacggcct ttacctgtgt 250

 cttccggtgt ttcccgtgcg acccatcctg tgggagtgcc tcgtgggctg 300

 ccccagagtt caccccacac tcagcagcac caatggtgaa gatgacaaga 350

 tcgaagactt tccaggcata tctgccctcc tgccaccgga cctacagctg 400

 cattcactgc agagctcact tggccaatca tgatgaacta atttccaagt 450

 cattccaagg aagtcaagga cgagcatacc tctttaactc agtagttaat 500

 gtgggctgtg ggcctgcaga agagcgagtg ttgctaacag gactgcatgc 550

 agtcgcagac atttactgtg aaaactgcaa aaccactctg ggctggaaat 600

 acgaacatgc ttttgaaagc agccagaaat ataaagaagg caaatacatc 650

 attgaactag cacacatgat caaggacaat ggctgggact gattggacag 700

 catctaccca acccagtgtc cacgtgaacg ccattcaacc gaacattctt 750

 cccaagcgtg agagagtgac tgacacttgg ttccatccat ttaggggcct 800

 tgccatccgg ggcatcctcc caccctgacg ccatctttct ggtgaccggc 850

 ctctaaatcg ctgtctctct gtctctttgc tttgtatctg tttgtgagtt 900

 gatcctggct tctctctctg ttctagtttt ggctgaaaac aaaacaacaa 950

 aaggaacaga tccttgaccg catggcggca gcccaccttg gtaagggccc 1000

 cagggcccat gcgagagctg cctgatggcc tcttgtcagg agagcagtgg 1050

 cacgggggcg tgaggaagag ggaaagggga aactctaagg gtcctggcgc 1100

 ggggaagggg tggaagggtg gaggtaggaa caaaattgcg ccgctcctgg 1150

 agacctgata acttaggctt gaaataattg acttgtctaa aaggacaaag 1200

 agaaaaaaaa aatacctcat gactgcattc tctctgacta gaagcttctg 1250

 ttcctgacac caaatgtgcc aggttagcaa atgagcacaa gatgtggccc 1300

 tgattctagt tggtggggca agggcctggt tctcctgggc tgagtggggg 1350

 agtgtcctgg cagcagcgag tgacctgggc agtggccagg tgggtgcgat 1400

 gactctgatg cctcactcag tctctgggca atcatcatct ttgcctctag 1450

 ccaccgtaga taaggtgtga agggactgct gtttgcaatg ggcttaccat 1500

 ccaaatatcc caaaggcttt gaccagcaac caagtaaaat cagtaattga 1550

 ggagagcagg gcacaaaggg gctgcagttt gggagctcct gaagaaatgg 1600

 ctcagatatt gagtcagaga aataaaaagt aggatcagtt agcaattcta 1650

 actgcccttc cttctgaccc ctcataagag gagtgtggtg agggagggga 1700

 ctgggtaggg gtcatcccag gaggaggggt ttacattgga accagttcag 1750

 gttcggtgca tctttcctct tcggttttac agtggcttcc gtgggatcgt 1800

 caatttcttg ttcttagagt ttcgggtgtt tttctccagt cttgttactg 1850

 tagactgtag aaagcacggg ccccaggctc tgagcttagt aataacctgg 1900

 ctggtagatt cctcatgccc ctaattgtcc cacttaggcc tgaatgtctt 1950

 gcatggagag aaatctcctg tcagtgtggt ccagcagcag ggaggagttc 2000

 tgcccaaatt ccgatatcac cccttccccc atccaaacat ccttcgatta 2050

 gggaagtgga gagcacatcc ctgtaaggcc cataagagaa agaggagttt 2100

 gttacattta atcaacactg tgaagtctgt tctacagcaa ttcagccatt 2150

 acacagtata tgactgaaac tcatttaact gggttaattt catttcttag 2200

 actgaatata ttattgttaa gatacgtgtg cgtgttaggt aattctcagc 2250

 atctcctcca agtaggccga ccttctcgga aaattcaccc taaaagtctc 2300

 acaaaagaat gagttcatgg ggagattctg taaagtgatg aactgagatg 2350

 aaagcagcca acagcccagg agcttttcag aatagcgtct gcagcagaac 2400

 cagtttccat tcagagcgcg tccttggtgg aaatgctttt ttgtgtgtct 2450

 ccacgcgctg atggtggaat gggagcccca agacgtgtgg gcttagaaat 2500

 caacttttgt tccccaaggc ttcttgtcca gatctttcca gtgctttcat 2550

 agccctggga gatcaagttg ttctccccac tttactgcaa ggtagactga 2600

 agttcagaag aaatactgaa tttctgctcc cagaagaata gtttctctgg 2650

 ctcacaggcc caagttctca atgaaatcgt tttttaactt tcacattcct 2700

 aagctggctt cccgtgcaca gaagccatgg atttcccctc tctcccttcc 2750

 ccctcctcaa ggaaatagtc ttcctttatg gattttcatt ggactctttc 2800

 ctcagcgatt gtcctggctg tttattgata gtccttccca taagaaaatg 2850

 gggttaaaca tggggtaggt attttgtctt tcaaactaca aatggaatgt 2900

 ggtgacataa actagacatg gggtgccctc aagtttccaa ggggaccaat 2950

 gtgccactgt tcttccttgg ggatgaggcc tttgactgtt ggatggatca 3000

 gagcaggctc cagtcagacc ctggttctga atgttttttt tttcggtgac 3050

 tatccagtga gccttcagtg ggtgcaaggc gccatacttg ctgtgagaga 3100

 gctgagtaga gtgttggttt ttccataact acagggggaa aaaaagtcat 3150

 taggctttcc ctttgtgtca gtgaaaccaa aagtgcttct tacaacgttc 3200

 gctctgttca tgggttgtct atctaacatt gagcagcatt ggagaggcca 3250

 cagctgagct atggagatgc taaattaact catggcctca gtcagttcat 3300

 tctttaattt cctcaccaaa ttattgactt agagcataac caaagacctc 3350

 attcattcac cccaggtggg ttgggggaat tggagtttgt tggtgaagtt 3400

 tgggggcggg gtgtggggag tagagacagg gtaaggggac gtgagaaagg 3450

 aaaaggcatg aagttctata cctcagccag cagctgcctt cgtttggaac 3500

 tgaagtccag ccagcagact ctctagctcc atctcccctg tgccacccta 3550

 ggtcatatga ccttggccac cttggagtag acccagaccc ctcgggaccc 3600

 gggacattag tctcaggctg ctgatggatt gatttgacat gaaccaaaca 3650

 cagccaaact cgatacccac aagctgtcag ctgaacctga ctgagtgttc 3700

 ttcctgagtt cacgaggata ggctagagtg catttttact ggtggatcag 3750

 tgtgtgcgaa agagatgacc ctttataaag agattttcaa gtggatatat 3800

 ataaaagaaa cagttgcttg taaaatatac ttttgtaaat aatatttaat 3850

 tttttaaata atatatttgg tgctgttttc tcagatcccc tgagagcact 3900

 ttttattttc cttttaaatt ctatggtttc ctttgcattt cttgaagtat 3950

 attttaaggg aaacagtgat caccaataca tgttttcagt tttttttttt 4000

 taaggtctct atcactttaa tctggatcaa ggctttgaag caatgcctct 4050

 ctgcattttt tccccagtgg aacagactct gcagtacatt aatcaggttg 4100

 agaattgaaa tattttcttg catcagtatt ggctagaaaa gaaaataaat 4150

 aaaaccaagt taatttagta gtaacaactt acagtgattc ttcctgttgg 4200

 aagaatttgc aacaaatcag aatcacgttt ttagttgtgc gtgtgcgcgc 4250

 acacgtgtgt aaaaagcact ttcgattgtg cctcctgttt tctcgagtgg 4300

 ggacacttta actacagttt acacctcggg cgcataaagt ttttcttctc 4350

 tttctctctg gttgtttctg tttctgagtg gaccaacagc agaacccacg 4400

 aggatttgtt ttgagtatgg agctgttgcg ggtttgctcc tttttcttgc 4450

 tttgcgtgct cagtttttac agactgtaaa ggagatgtgt tgtttgtgaa 4500

 gatggagcag agtcaaatct gtgcttctaa ctgagatgag agtgtattaa 4550

 tcacgtatcg cagggctcca gctgttttag aagccacatc atgttaaaca 4600

 ttaactggtt tggattaaaa gaacattaat attataatac acatatctta 4650

 gtggtaaaca gctttttttt tttaaggtca gattgcctca ggtttagaaa 4700

 gaggctgaga aatcaaatct tgaacacaat caacttacat attttaaagg 4750

 aatctgcctc aaatgagaaa atatgctagt tatctagata gaggaaagag 4800

 atatttactt ttttaaaaat taaaatagtt atgaaatctg gcagaaaagg 4850

 taaagcctag aagaaactat gaaagctatt ctcatgttac caaattctat 4900

 ctgcgcatat gtttttgtat aacatttcgg tgacagtggg agtcggttcc 4950

 ctttcccaac ctgcagagac tatcttccaa tacagaatct gtctatttat 5000

 gcttgtgttt acaaactgta tttgttgggt ttgggttttt gttttctttg 5050

 gtggcatttt tcaggtcact ttgcttctat aacaaaggta attgttttca 5100

 aataatttgt cttcaccttt tcctgtattt gtacatagtg attcagtatt 5150

 agagaaaagt gcattgtttc tgtcatattt ccaatctgtg ttggtgctca 5200

 tttgagaaaa taaaagtttt caaatattac aaaaaaatct atgtcgggtg 5250

 cggagaaaga ggtaatgaaa tggcagg 5277

<210> 4456
<211> 112
<212> PRT
<213> Homo sapien

<400> 4456
 Val Gly Arg Gly Gly Gly Gly Asp Cys Gly Phe Lys Ser Val Pro
   1               5                  10                  15

 Gly Ala Arg Ala Pro Ala Gly Pro Arg Phe Ala Ala Ala His Pro
                  20                  25                  30

 Ser Gly Ala Lys Pro His Ala Gly Arg Thr Gly Pro Pro Val Ala
                  35                  40                  45

 Gly Leu Leu Arg Thr Ser Pro Arg Pro Leu Arg Glu Gly Ser Ser
                  50                  55                  60

 Ala Glu Asp Ile Thr Ser Val Trp Ser Leu Pro His Pro Pro Ala
                  65                  70                  75

 Ala Lys Pro Arg Pro Leu Pro Val Ser Ser Gly Val Ser Arg Ala
                  80                  85                  90

 Thr His Pro Val Gly Val Pro Arg Gly Leu Pro Gln Ser Ser Pro
                  95                 100                 105

 His Thr Gln Gln His Gln Trp
                 110

<210> 4457
<211> 1442
<212> DNA
<213> Homo sapien

<400> 4457
 gcgtgaggca ccgcggctgg cctgagtttc ttcttaatac tgtatcacaa 50

 ttgtgggctg tcttatgtgt tgatatcgat tgagctattt gaaataggaa 100

 tgttaatggg tgtattaaat ttttgtaagg atataacaat atctaccttc 150

 caaggatgtt gtgaggtttt ccatgatttt gtatatgagc taatgttacc 200

 tttgaggggt ggtgtgcatt atgttggatg attgtaaatt ttcagtggaa 250

 aatgtaccgt gtcctaaatt taaagacatg aaaaatatcc caagatcata 300

 ctagatcata atagcaattc ctttacaaat gaattatgga ggtaactgat 350

 ctctaacagt ttccttcatg ttgttttaat gcacaagggc agaggatctg 400

 ctgacccttg gaaccagcgt gagctaacca cgtgctatag acacttcatg 450

 gtgtcgcacc cagggaagtc aaagcgcttt gctccctcac tgtctgtgag 500

 tcctcagcca ttagtacccc accccccgct gctccaaaac ttgagttatt 550

 tcaaatgttt ctcactgttc atctctccac tgaccccact ccagaaagcc 600

 tggagagagt cccaagatgc cacccacctt ccccaatccc tcgccacaga 650

 tctgtgtcta tctcacactc tgtaagtgcc gctttgcttc ttcctctctt 700

 gaaaagactg agaacacaca ttttaacatg ttaggaaaat ggggcagcct 750

 aaaaaatgac tgatcccacc gccagtgact catgtatact ccaggctagc 800

 agacaaggcc ctttttggtg ggcctgcttc tgtgggttca cagaaaccaa 850

 attactgtgg gttgcaaaga attagcaggt catttacaaa gcagacatcc 900

 cttcacccag actgtggttt tgcatgctca ggttctcagt ctatgagctt 950

 tggtgcagga tcattttggc tactggaaaa accatagctt attttaaatt 1000

 tctggttgcc aaagccacca cacgtgtggt ctgtggatga ccattgtctg 1050

 cagaatgacg aggaaggaac agaatgtggt ttggggctca gggtggcctt 1100

 cccactggga gggaaggcgg gagggagccc ttgccctggg ttttgacaca 1150

 gcctgtgctc acagcctctc ctctcatctg catttctcag aaatgccctc 1200

 cctgcccagt ggtgactttc cctcgtcact cctatggagt tctacctgga 1250

 gcccagccat gtgtggaact gtgaagttta ctcctctgta aagatggttt 1300

 aaagaaagtc agcttctgaa atgtaacaat gctaaccctt gctggaaccc 1350

 tgtaagaaat agccctgctg atagttttct aggtttatca tgtttgattt 1400

 ttacactgaa aaataaaaaa atcctggtat gtttgaaaaa aa 1442

<210> 4458
<211> 84
<212> PRT
<213> Homo sapien

<400> 4458
 Met Thr Ile Val Cys Arg Met Thr Arg Lys Glu Gln Asn Val Val
   1               5                  10                  15

 Trp Gly Ser Gly Trp Pro Ser His Trp Glu Gly Arg Arg Glu Gly
                  20                  25                  30

 Ala Leu Ala Leu Gly Phe Asp Thr Ala Cys Ala His Ser Leu Ser
                  35                  40                  45

 Ser His Leu His Phe Ser Glu Met Pro Ser Leu Pro Ser Gly Asp
                  50                  55                  60

 Phe Pro Ser Ser Leu Leu Trp Ser Ser Thr Trp Ser Pro Ala Met
                  65                  70                  75

 Cys Gly Thr Val Lys Phe Thr Pro Leu
                  80

<210> 4459
<211> 10156
<212> DNA
<213> Homo sapien

<400> 4459
 gcggccgctc ccccggagcg gctaaagcgg cggcgaccga ggcgagcaat 50

 gggcacggca gtctcggcag agcacaggcg cttcaccgcg gctgctcggg 100

 ctccgcgctg acctgcccgg gcggccgcct attgtctttc tccgcggcga 150

 aggtgaagag ttgtcccagc tcggcccgcg ggggagcccc gggagccgca 200

 cgtgtcctgg gtcatgaaac ttaatccaca gcaagctccc ttatatggtg 250

 attgtgttgt tacagtgctg cttgctgaag aggacaaagc tgaagatgat 300

 gtagtgtttt acttggtatt tttgggttcc accctccgtc actgtacaag 350

 tactcggaag gtcagttctg atacattgga gaccattgct cctggtcatg 400

 attgttgtga aacagtgaag gtgcagctct gtgcttccaa agagggcctt 450

 cccgtgtttg tggtggctga agaagacttt catttcgtcc aggatgaagc 500

 gtatgatgca gctcaattcc tagcaaccag tgctggaaat cagcaggctt 550

 tgaactttac ccgttttctt gaccagtcag gacccccatc tggggatgtg 600

 aattcccttg ataagaagtt ggtgctggca ttcaggcacc tgaagctgcc 650

 cacggagtgg aatgtattgg ggacagatca gagtttgcat gatgctggcc 700

 cgcgagagac attgatgcat tttgctgtgc ggctgggact gctgaggttg 750

 acgtggttcc tgttgcagaa gccaggtggc cgcggagctc tcagtatcca 800

 caaccaggaa ggggcgacgc ctgtgagctt ggccttggag cgaggctatc 850

 acaagctgca ccagcttcta accgaggaga atgctggaga accagactcc 900

 tggagcagtt tatcctatga aataccgtat ggagactgtt ctgtgaggca 950

 tcatcgagag ttggacatct atacattaac ctctgagtct gattcacatc 1000

 atgaacaccc atttcctgga gacggttgca ctggaccaat ttttaaactt 1050

 atgaacatcc aacagcaact aatgaaaaca aacctcaagc agatggacag 1100

 tcttatgccc ttaatgatga cagcacagga tccttccagt gccccagaga 1150

 cagatggcca gtttcttccc tgtgcaccgg agcccacgga ccctcagcga 1200

 ctttcttctt ctgaagagac tgagagcact cagtgctgcc cagggagccc 1250

 tgttgcacag actgaaagtc cctgtgattt gtcaagcata gttgaggagg 1300

 agaatacaga ccgttcctgt aggaagaaaa ataaaggcgt ggaaagaaaa 1350

 ggggaagagg tggagccagc acctattgtg gactctggaa ctgtatctga 1400

 tcaagacagc tgccttcaga gcttgcctga ttgtggagta aagggcacgg 1450

 aaggcctttc gtcctgtgga aacagaaatg aagaaactgg aacaaaatct 1500

 tctggaatgc ccacagacca ggagtccctg agcagtggag atgctgtgct 1550

 tcagagagac ttggtcacgg agccaggcac agcccagtat tcctctggag 1600

 gtgaactggg aggcatttca acaacaaatg tcagtacccc agacactgca 1650

 ggggaaatgg aacatgggct catgaaccca gatgccactg ttcggaagaa 1700

 tgtgcttcag ggaggggaaa gtacaaagga aagatttgag aactctaata 1750

 ttggcacagc tggagcctct gacgtgcacg tcacaagtaa gcctgtggat 1800

 aaaatcagtg ttccaaactg tgcccctgcc gccagttccc tggatggtaa 1850

 caaacctgct gagtcttcac ttgcatttag taatgaagaa acctccactg 1900

 aaaaaacagc agaaacggaa acttcacgaa gttgtgagga gagtgctgat 1950

 gctccagtag atcagaattc tgtggtgatt ccagctgctg caaaagacaa 2000

 gatttcagat ggattagaac cttatactct cttagcagca ggcataggtg 2050

 aggcaatgtc accctcagat ttagcccttc ttgggctgga agaagatgta 2100

 atgccacacc agaactcaga aacaaattca tctcatgctc aaagccaaaa 2150

 gggcaaatcc tcacccattt gttctacaac tggagacgat aaactttgtg 2200

 cagactctgc atgtcaacag aacacagtga cttctagtgg cgatttggtt 2250

 gcaaaactgt gtgataacat agttagcaag tccgaaagca ccacagcaag 2300

 gcaacccagc tcacaagatc cacccgatgc ctcccactgt gaagacccac 2350

 aggctcatac agtcacctct gaccctgtaa gggataccca ggaacgtgcg 2400

 gatttttgtc ctttcaaagt ggtggataac aaaggccaac gaaaagatgt 2450

 gaaactagat aaacctttaa caaatatgct tgaggtggtt tcacatccac 2500

 atccagttgt ccctaaaatg gagaaagaac tggtgccaga ccaggcagta 2550

 atatcagaca gtactttctc tctggcaaac agtccaggca gtgaatcagt 2600

 aaccaaggat gacgcacttt cttttgtccc ctcccagaaa gaaaagggaa 2650

 cagcaactcc tgaactacat acagctacag attatagaga tggcccagat 2700

 ggaaattcga atgagcctga tacgcggcca ctagaagaca gggcagcagg 2750

 cctgtccaca tcctccactg ctgcagagct tcagcacggg atggggaata 2800

 ccagtctcac aggacttggt ggagagcatg agggtcctgc ccctccagca 2850

 atcccagaag ctctgaatat caaggggaac actgactctt ccctgcaaag 2900

 tatgggtaag gccactttgg ctttagattc agttttgact gaagaaggaa 2950

 aacttctggt ggtttcagaa agctctgcag ctcaggaaca agataaggat 3000

 aaagcggtga cctgttcctc tattaaggaa aatgctctct cttcaggaac 3050

 tttgcaggaa gagcagagaa caccacctcc tggacaagat actcaacaat 3100

 ttcatgaaaa atcaatctca gctgactgtg ccaaggacaa agcacttcag 3150

 ctaagtaatt caccgggtgc atcctctgcc tttcttaagg cagaaactga 3200

 acataacaag gaagtggccc cacaagtctc actgctgact caaggtgggg 3250

 ctgcccagag cctggtgcca ccaggagcaa gtctggccac agagtcaagg 3300

 caggaagcct tgggggcaga gcacaacagc tccgctctgt tgccatgtct 3350

 gttgccagat gggtctgatg ggtccgatgc tcttaactgc agtcaggctt 3400

 ctcctctgga tgttggagtg aagaacactc aatcccaggg aaaaactagt 3450

 gcctgtgagg tgagtggaaa tgtgacggtg gatgttacag gggttaatgc 3500

 tctacaaggt atggctgagc ccagaagaga gaatatatca cacaacaccc 3550

 aagacatcct gattccaaac gtcttgttga gccaagagaa gaatgccgtt 3600

 ctaggtttgc cagtggctct acaggacaaa gctgtgactg acccacaggg 3650

 agttggaacc ccagagatga tacctcttga ttgggagaaa gggaagctgg 3700

 agggagcaga ccacagctgt accatgggtg acgctgagga agcccaaata 3750

 gacgatgaag cacatcctgt cctactgcag cctgttgcca aggagctccc 3800

 cacagacatg gagctctcag cccatgatga tggggcccca gctggtgtga 3850

 gggaagtcac gcgagccccg ccttcaggca gagaaaggag cactccctct 3900

 ctaccttgca tggtctctgc ccaggacgca cctctgccta agggggcaga 3950

 cttgatagag gaggctgcca gccgtatagt ggatgctgtc atcgaacaag 4000

 tcaaggccgc tggagcactg cttactgagg gggaggcctg tcacatgtca 4050

 ctgtccagcc ctgagttggg tcctctcact aaaggactag agagtgcttt 4100

 tacagaaaaa gtgagtactt tcccacctgg ggagagccta ccaatgggca 4150

 gtactcctga ggaagccacg gggagccttg caggatgttt tgctggaagg 4200

 gaggagccag agaagatcat tttacctgtc caggggcctg agccagcagc 4250

 agaaatgcca gacgtgaaag ctgaagatga agtggatttt agagcaagtt 4300

 caatttctga agaagtggct gtagggagca tagctgctac actgaagatg 4350

 aagcaaggcc caatgaccca ggcgataaac cgagaaaact ggtgtacaat 4400

 agagccatgc cctgatgcag catctcttct ggcttccaag cagagcccag 4450

 aatgtgagaa cttcctggat gttggactgg gcagagagtg tacctcaaaa 4500

 caaggtgtac ttaaaagaga atctgggagt gattctgacc tctttcactc 4550

 acccagtgat gacatggaca gcatcatctt cccaaagcca gaggaagagc 4600

 atttggcctg tgatatcacc ggatccagtt catccaccga tgacacggct 4650

 tcactggacc gacattcttc tcatggcagt gatgtgtctc tctcccagat 4700

 tttaaagcca aacaggtcaa gagatcggca aagccttgat ggattctaca 4750

 gccatgggat gggagctgag ggtcgagaaa gtgagagtga gcctgctgac 4800

 ccaggcgacg tggaggagga ggagatggac agtatcactg aagtgcctgc 4850

 aaactgctct gtcctaagga gctccatgcg ctctctttct cccttccgga 4900

 ggcacagctg ggggcctggg aaaaatgcag ccagcgatgc agaaatgaac 4950

 caccggagtt caatgcgagt tcttggggat gttgtcagga gacctcccat 5000

 tcataggaga agtttcagtc tagaaggctt gacaggagga gctggtgtcg 5050

 gaaacaagcc atcctcatct ctagaagtaa gctctgcaaa tgccgaagag 5100

 ctcagacacc cattcagtgg tgaggaacgg gttgactctt tggtgtcact 5150

 ttcagaagag gatctggagt cagaccagag agaacatagg atgtttgatc 5200

 agcagatatg tcacagatct aagcagcagg gatttaatta ctgtacatca 5250

 gccatttcct ctccattgac aaaatccatc tcattaatga caatcagcca 5300

 tcctggattg gacaattcac ggcccttcca cagtaccttc cacaatacca 5350

 gtgctaatct gactgagagt ataacagaag agaactataa tttcctgcca 5400

 catagcccct ccaagaaaga ttctgaatgg aagagtggaa caaaagtcag 5450

 tcgtacattc agctacatca agaataaaat gtctagcagc aagaagagca 5500

 aagaaaagga aaaagaaaaa gataagatta aggagaagga gaaagattct 5550

 aaagacaagg agaaagataa gaagactgtc aacgggcaca ctttcagttc 5600

 cattcctgtt gtgggtccca tcagctgtag ccagtgtatg aagcccttca 5650

 ccaacaaaga tgcctatact tgtgcaaatt gcagtgcttt tgtccacaaa 5700

 ggctgccgag aaagtctagc ctcctgtgca aaggtcaaaa tgaagcagcc 5750

 caaagggagc cttcaggcac atgacacatc atcactgccc acggtcatta 5800

 tgagaaacaa gccctcacag cccaaggagc gtcctcggtc cgcagtcctc 5850

 ctggtggatg aaaccgctac caccccaata tttgccaata gacgatccca 5900

 gcagagtgtc tcgctctcca aaagtgtctc catacagaac attactggag 5950

 ttggcaatga tgagaacatg tcaaacacct ggaaattcct gtctcattca 6000

 acagactcac taaataaaat cagcaaggtc aatgagtcaa cagaatcact 6050

 tactgatgag ggagtaggta cagacatgaa tgaaggacaa ctactgggag 6100

 actttgagat tgagtccaaa cagctggaag cagagtcttg gagtcggata 6150

 atagacagca agtttctaaa acagcaaaag aaagatgtgg tcaaacggca 6200

 agaagtaata tatgagttga tgcagacaga gtttcatcat gtccgcactc 6250

 tcaagatcat gagtggtgtg tacagccagg ggatgatggc ggatctgctt 6300

 tttgagcagc agatggtaga aaagctgttc ccctgtttgg atgagctgat 6350

 cagtatccat agccaattct tccagaggat tctggagcgg aagaaggagt 6400

 ctctggtgga taaaagtgaa aagaactttc tcatcaagag gataggggat 6450

 gtgcttgtaa atcagttttc aggtgagaat gcagaacgtt taaagaagac 6500

 atatggcaag ttttgtgggc aacataacca gtctgtaaac tacttcaaag 6550

 acctttatgc caaggataag cgttttcaag cctttgtaaa gaagaagatg 6600

 agcagttcag ttgttagaag gcttggaatt ccagagtgca tattgcttgt 6650

 aactcagcgg attaccaagt acccagtttt attccaaaga atattgcagt 6700

 gtaccaaaga caatgaagtg gagcaggaag atctagcaca gtccttgagc 6750

 ctggtgaagg atgtgattgg agctgtagac agcaaagtgg caagttatga 6800

 aaagaaagtg cgtctcaatg agatttatac aaagacagat agcaagtcaa 6850

 tcatgaggat gaagagtggt cagatgtttg ccaaggaaga tttgaaacgg 6900

 aagaagcttg tacgtgatgg gagtgtgttt ctgaagaatg cagcaggaag 6950

 gttgaaagag gttcaagcag ttcttctcac tgacatttta gttttccttc 7000

 aagaaaaaga ccagaagtac atctttgcat cattggacca gaagtcaaca 7050

 gtgatctctt taaagaagct gattgtgaga gaagtggcac atgaggagaa 7100

 aggtttattc ctgatcagca tggggatgac agatccagag atggtagaag 7150

 tccatgccag ctccaaagag gaacgaaaca gctggattca gatcattcag 7200

 gacacaatca acaccctgaa cagagatgaa gatgaaggaa ttcctagtga 7250

 gaatgaggaa gaaaagaaaa tgttggacac cagagcccga gaattaaaag 7300

 aacaacttca ccagaaggac caaaaaatcc tactcttgtt ggaagagaag 7350

 gagatgattt tccgggacat ggctgagtgc agcacccctc tcccagagga 7400

 ttgctcccca acacatagcc ctagagttct cttccgctcc aacacagaag 7450

 aggctctcaa aggaggacct ttaatgaaaa gtgcaataaa tgaggtggag 7500

 atccttcagg gtttggtgag tggaaatctg ggaggcacac ttgggccgac 7550

 tgtcagcagc cccattgagc aagatgtggt cggtcccgtt tccctgcccc 7600

 ggagagcaga gacctttgga ggatttgaca gccatcagat gaatgcttca 7650

 aaaggaggcg agaaggaaga gggagatgat ggccaagatc ttaggagaac 7700

 ggaatcagat agtggcctaa aaaagggtgg aaatgctaac ctggtattta 7750

 tgcttaaaag aaacagtgag caggttgtcc agagcgttgt tcatctctac 7800

 gagctcctca gcgctctgca gggtgtggtg ctgcagcagg acagctacat 7850

 tgaggaccag aaactggtgc tgagcgagag ggcgctcact cgcagcttgt 7900

 cccgcccgag ctccctcatt gagcaggaga agcagcgcag cctggagaag 7950

 cagcgccagg acctggccaa cctgcagaag cagcaggccc agtacctcga 8000

 ggagaagcgc aggcgcgagc gtgagtggga agctcgtgag agggagctgc 8050

 gggagcggga ggccctcctg gcccagcgcg aggaggaggt gcagcagggg 8100

 cagcaggacc tggaaaagga gcgggaggag ctccagcaga agaagggcac 8150

 ataccagtat gacctggagc gactgcgtgc tgcccagaaa cagcttgaga 8200

 gggaacagga gcacgtgcgc cgggaggcag agcggctcag ccagcggcag 8250

 acagaacggg acctgtgtca ggtttcccat ccacatacca agctgatgag 8300

 gatcccatcg ttcttcccca gtcctgagga gcccccctcg ccatctgcac 8350

 cttccatagc caaatcaggg tcattggact cagaactttc agtgtcccca 8400

 aaaaggaaca gcatctctcg gacacacaaa gataaggggc cttttcacat 8450

 actgagttca accagccaga caaacaaagg accagaaggg cagagccagg 8500

 cccctgcgtc cacctctgcc tctacccgcc tgtttgggtt aacaaagcca 8550

 aaggaaaaga aggagaaaaa aaagaagaac aaaaccagcc gctctcagcc 8600

 cggtgatggt cccgcgtcag aagtatcagc agagggtgaa gagatcttct 8650

 gctgactctc ttcctctctg ctgaggcagc tgcctcctga tcctggccag 8700

 cccacctctc ctgctgtccc cgcgtgcaca agtctcttac actggacgcc 8750

 cactgctcct cagcgtccag tcctcctggg cggccccagg tcctggacaa 8800

 taagcaacag atgatattga gtgtcgggtg gggaaggagg cccagactct 8850

 gcttcggcca tgatttgtga ctgcccagga ctctcaggtt gggctggccc 8900

 tactcaggat tacactgaaa gtaatggcct cgtaagtaca ggtgatggtt 8950

 ttggacacgt caggaattcc taaaggctga aagagtgtat ccaagtaagg 9000

 tctgaacctc cgactgcctt ttatttgggg gaacacaaaa ccaaacagca 9050

 gatgttttgg acttgatctg tgtacgtaca tggggacctg tctgcatata 9100

 cacacgggga atgccagaag aaggcccagt ctgcaccagg cgtctggtca 9150

 acttagcaca agggcagtgc ctggacggac ccggagcccc cgcatatcag 9200

 cagttcaccc agtactcctc agagactggt ttccctctaa acccatcccg 9250

 ggcacatacc acccctgttt tgcatgtatt tctcatttca ttttagggat 9300

 gacaaacatt tgtgaaacca gtgagagaag tcttgatgtg tataaaagac 9350

 gtgatgtgca ccacctcgat ctcggtgttt caggcactaa agcaacaaaa 9400

 caacccatag tatctcattt tgtcatcaga tccagaagaa atatcctggt 9450

 tttccagcat gtttacccac atgttttggg catggataaa gtgaagaggc 9500

 ctactcacca ttatccctgc agcgtgacac cttttgattg tcactgacca 9550

 ctcagaaggg gccacggcct cctggctgtg ttcctgagcc cccgtcgtgc 9600

 ctctcccaga cagcagctgt ctggcccttg ctgggtgagg gcacaccact 9650

 gccaggggtc agcctcgcac ccaggccagg cagaagctgt gctctgaagc 9700

 taggacagct ggctgagaag tgggttcagg cgaagggtga agccatgtgt 9750

 agcagttcct gccagtgcag atctggagag gagctggccc ggaaggcgtg 9800

 gttgtgaaag cgcccttctt atgttaggag gccttggcaa aattggattt 9850

 cttcaaaaat acatgtaaag gtctgttgtt gaattgtact ctgcccctgg 9900

 aagcagatac agatggctgc ctgctgctcg gctttgcttt tgcttttccc 9950

 accgtgtttt catctttgtt cacttgaggc tttccccagc tggtgtgtgc 10000

 aggacagttc atggtaatgt tgccctctga ggccccgtac accagaaggg 10050

 aggccctgga aaattttgtg cttccagcgt ggccttcaat tcttgctttt 10100

 ttgcccctca gaagcatggg gcttttgagc acacttaaaa aaaaaaaccg 10150

 gaattc 10156

<210> 4460
<211> 2813
<212> PRT
<213> Homo sapien

<400> 4460
 Met Lys Leu Asn Pro Gln Gln Ala Pro Leu Tyr Gly Asp Cys Val
   1               5                  10                  15

 Val Thr Val Leu Leu Ala Glu Glu Asp Lys Ala Glu Asp Asp Val
                  20                  25                  30

 Val Phe Tyr Leu Val Phe Leu Gly Ser Thr Leu Arg His Cys Thr
                  35                  40                  45

 Ser Thr Arg Lys Val Ser Ser Asp Thr Leu Glu Thr Ile Ala Pro
                  50                  55                  60

 Gly His Asp Cys Cys Glu Thr Val Lys Val Gln Leu Cys Ala Ser
                  65                  70                  75

 Lys Glu Gly Leu Pro Val Phe Val Val Ala Glu Glu Asp Phe His
                  80                  85                  90

 Phe Val Gln Asp Glu Ala Tyr Asp Ala Ala Gln Phe Leu Ala Thr
                  95                 100                 105

 Ser Ala Gly Asn Gln Gln Ala Leu Asn Phe Thr Arg Phe Leu Asp
                 110                 115                 120

 Gln Ser Gly Pro Pro Ser Gly Asp Val Asn Ser Leu Asp Lys Lys
                 125                 130                 135

 Leu Val Leu Ala Phe Arg His Leu Lys Leu Pro Thr Glu Trp Asn
                 140                 145                 150

 Val Leu Gly Thr Asp Gln Ser Leu His Asp Ala Gly Pro Arg Glu
                 155                 160                 165

 Thr Leu Met His Phe Ala Val Arg Leu Gly Leu Leu Arg Leu Thr
                 170                 175                 180

 Trp Phe Leu Leu Gln Lys Pro Gly Gly Arg Gly Ala Leu Ser Ile
                 185                 190                 195

 His Asn Gln Glu Gly Ala Thr Pro Val Ser Leu Ala Leu Glu Arg
                 200                 205                 210

 Gly Tyr His Lys Leu His Gln Leu Leu Thr Glu Glu Asn Ala Gly
                 215                 220                 225

 Glu Pro Asp Ser Trp Ser Ser Leu Ser Tyr Glu Ile Pro Tyr Gly
                 230                 235                 240

 Asp Cys Ser Val Arg His His Arg Glu Leu Asp Ile Tyr Thr Leu
                 245                 250                 255

 Thr Ser Glu Ser Asp Ser His His Glu His Pro Phe Pro Gly Asp
                 260                 265                 270

 Gly Cys Thr Gly Pro Ile Phe Lys Leu Met Asn Ile Gln Gln Gln
                 275                 280                 285

 Leu Met Lys Thr Asn Leu Lys Gln Met Asp Ser Leu Met Pro Leu
                 290                 295                 300

 Met Met Thr Ala Gln Asp Pro Ser Ser Ala Pro Glu Thr Asp Gly
                 305                 310                 315

 Gln Phe Leu Pro Cys Ala Pro Glu Pro Thr Asp Pro Gln Arg Leu
                 320                 325                 330

 Ser Ser Ser Glu Glu Thr Glu Ser Thr Gln Cys Cys Pro Gly Ser
                 335                 340                 345

 Pro Val Ala Gln Thr Glu Ser Pro Cys Asp Leu Ser Ser Ile Val
                 350                 355                 360

 Glu Glu Glu Asn Thr Asp Arg Ser Cys Arg Lys Lys Asn Lys Gly
                 365                 370                 375

 Val Glu Arg Lys Gly Glu Glu Val Glu Pro Ala Pro Ile Val Asp
                 380                 385                 390

 Ser Gly Thr Val Ser Asp Gln Asp Ser Cys Leu Gln Ser Leu Pro
                 395                 400                 405

 Asp Cys Gly Val Lys Gly Thr Glu Gly Leu Ser Ser Cys Gly Asn
                 410                 415                 420

 Arg Asn Glu Glu Thr Gly Thr Lys Ser Ser Gly Met Pro Thr Asp
                 425                 430                 435

 Gln Glu Ser Leu Ser Ser Gly Asp Ala Val Leu Gln Arg Asp Leu
                 440                 445                 450

 Val Thr Glu Pro Gly Thr Ala Gln Tyr Ser Ser Gly Gly Glu Leu
                 455                 460                 465

 Gly Gly Ile Ser Thr Thr Asn Val Ser Thr Pro Asp Thr Ala Gly
                 470                 475                 480

 Glu Met Glu His Gly Leu Met Asn Pro Asp Ala Thr Val Arg Lys
                 485                 490                 495

 Asn Val Leu Gln Gly Gly Glu Ser Thr Lys Glu Arg Phe Glu Asn
                 500                 505                 510

 Ser Asn Ile Gly Thr Ala Gly Ala Ser Asp Val His Val Thr Ser
                 515                 520                 525

 Lys Pro Val Asp Lys Ile Ser Val Pro Asn Cys Ala Pro Ala Ala
                 530                 535                 540

 Ser Ser Leu Asp Gly Asn Lys Pro Ala Glu Ser Ser Leu Ala Phe
                 545                 550                 555

 Ser Asn Glu Glu Thr Ser Thr Glu Lys Thr Ala Glu Thr Glu Thr
                 560                 565                 570

 Ser Arg Ser Cys Glu Glu Ser Ala Asp Ala Pro Val Asp Gln Asn
                 575                 580                 585

 Ser Val Val Ile Pro Ala Ala Ala Lys Asp Lys Ile Ser Asp Gly
                 590                 595                 600

 Leu Glu Pro Tyr Thr Leu Leu Ala Ala Gly Ile Gly Glu Ala Met
                 605                 610                 615

 Ser Pro Ser Asp Leu Ala Leu Leu Gly Leu Glu Glu Asp Val Met
                 620                 625                 630

 Pro His Gln Asn Ser Glu Thr Asn Ser Ser His Ala Gln Ser Gln
                 635                 640                 645

 Lys Gly Lys Ser Ser Pro Ile Cys Ser Thr Thr Gly Asp Asp Lys
                 650                 655                 660

 Leu Cys Ala Asp Ser Ala Cys Gln Gln Asn Thr Val Thr Ser Ser
                 665                 670                 675

 Gly Asp Leu Val Ala Lys Leu Cys Asp Asn Ile Val Ser Lys Ser
                 680                 685                 690

 Glu Ser Thr Thr Ala Arg Gln Pro Ser Ser Gln Asp Pro Pro Asp
                 695                 700                 705

 Ala Ser His Cys Glu Asp Pro Gln Ala His Thr Val Thr Ser Asp
                 710                 715                 720

 Pro Val Arg Asp Thr Gln Glu Arg Ala Asp Phe Cys Pro Phe Lys
                 725                 730                 735

 Val Val Asp Asn Lys Gly Gln Arg Lys Asp Val Lys Leu Asp Lys
                 740                 745                 750

 Pro Leu Thr Asn Met Leu Glu Val Val Ser His Pro His Pro Val
                 755                 760                 765

 Val Pro Lys Met Glu Lys Glu Leu Val Pro Asp Gln Ala Val Ile
                 770                 775                 780

 Ser Asp Ser Thr Phe Ser Leu Ala Asn Ser Pro Gly Ser Glu Ser
                 785                 790                 795

 Val Thr Lys Asp Asp Ala Leu Ser Phe Val Pro Ser Gln Lys Glu
                 800                 805                 810

 Lys Gly Thr Ala Thr Pro Glu Leu His Thr Ala Thr Asp Tyr Arg
                 815                 820                 825

 Asp Gly Pro Asp Gly Asn Ser Asn Glu Pro Asp Thr Arg Pro Leu
                 830                 835                 840

 Glu Asp Arg Ala Ala Gly Leu Ser Thr Ser Ser Thr Ala Ala Glu
                 845                 850                 855

 Leu Gln His Gly Met Gly Asn Thr Ser Leu Thr Gly Leu Gly Gly
                 860                 865                 870

 Glu His Glu Gly Pro Ala Pro Pro Ala Ile Pro Glu Ala Leu Asn
                 875                 880                 885

 Ile Lys Gly Asn Thr Asp Ser Ser Leu Gln Ser Met Gly Lys Ala
                 890                 895                 900

 Thr Leu Ala Leu Asp Ser Val Leu Thr Glu Glu Gly Lys Leu Leu
                 905                 910                 915

 Val Val Ser Glu Ser Ser Ala Ala Gln Glu Gln Asp Lys Asp Lys
                 920                 925                 930

 Ala Val Thr Cys Ser Ser Ile Lys Glu Asn Ala Leu Ser Ser Gly
                 935                 940                 945

 Thr Leu Gln Glu Glu Gln Arg Thr Pro Pro Pro Gly Gln Asp Thr
                 950                 955                 960

 Gln Gln Phe His Glu Lys Ser Ile Ser Ala Asp Cys Ala Lys Asp
                 965                 970                 975

 Lys Ala Leu Gln Leu Ser Asn Ser Pro Gly Ala Ser Ser Ala Phe
                 980                 985                 990

 Leu Lys Ala Glu Thr Glu His Asn Lys Glu Val Ala Pro Gln Val
                 995                1000                1005

 Ser Leu Leu Thr Gln Gly Gly Ala Ala Gln Ser Leu Val Pro Pro
                1010                1015                1020

 Gly Ala Ser Leu Ala Thr Glu Ser Arg Gln Glu Ala Leu Gly Ala
                1025                1030                1035

 Glu His Asn Ser Ser Ala Leu Leu Pro Cys Leu Leu Pro Asp Gly
                1040                1045                1050

 Ser Asp Gly Ser Asp Ala Leu Asn Cys Ser Gln Ala Ser Pro Leu
                1055                1060                1065

 Asp Val Gly Val Lys Asn Thr Gln Ser Gln Gly Lys Thr Ser Ala
                1070                1075                1080

 Cys Glu Val Ser Gly Asn Val Thr Val Asp Val Thr Gly Val Asn
                1085                1090                1095

 Ala Leu Gln Gly Met Ala Glu Pro Arg Arg Glu Asn Ile Ser His
                1100                1105                1110

 Asn Thr Gln Asp Ile Leu Ile Pro Asn Val Leu Leu Ser Gln Glu
                1115                1120                1125

 Lys Asn Ala Val Leu Gly Leu Pro Val Ala Leu Gln Asp Lys Ala
                1130                1135                1140

 Val Thr Asp Pro Gln Gly Val Gly Thr Pro Glu Met Ile Pro Leu
                1145                1150                1155

 Asp Trp Glu Lys Gly Lys Leu Glu Gly Ala Asp His Ser Cys Thr
                1160                1165                1170

 Met Gly Asp Ala Glu Glu Ala Gln Ile Asp Asp Glu Ala His Pro
                1175                1180                1185

 Val Leu Leu Gln Pro Val Ala Lys Glu Leu Pro Thr Asp Met Glu
                1190                1195                1200

 Leu Ser Ala His Asp Asp Gly Ala Pro Ala Gly Val Arg Glu Val
                1205                1210                1215

 Thr Arg Ala Pro Pro Ser Gly Arg Glu Arg Ser Thr Pro Ser Leu
                1220                1225                1230

 Pro Cys Met Val Ser Ala Gln Asp Ala Pro Leu Pro Lys Gly Ala
                1235                1240                1245

 Asp Leu Ile Glu Glu Ala Ala Ser Arg Ile Val Asp Ala Val Ile
                1250                1255                1260

 Glu Gln Val Lys Ala Ala Gly Ala Leu Leu Thr Glu Gly Glu Ala
                1265                1270                1275

 Cys His Met Ser Leu Ser Ser Pro Glu Leu Gly Pro Leu Thr Lys
                1280                1285                1290

 Gly Leu Glu Ser Ala Phe Thr Glu Lys Val Ser Thr Phe Pro Pro
                1295                1300                1305

 Gly Glu Ser Leu Pro Met Gly Ser Thr Pro Glu Glu Ala Thr Gly
                1310                1315                1320

 Ser Leu Ala Gly Cys Phe Ala Gly Arg Glu Glu Pro Glu Lys Ile
                1325                1330                1335

 Ile Leu Pro Val Gln Gly Pro Glu Pro Ala Ala Glu Met Pro Asp
                1340                1345                1350

 Val Lys Ala Glu Asp Glu Val Asp Phe Arg Ala Ser Ser Ile Ser
                1355                1360                1365

 Glu Glu Val Ala Val Gly Ser Ile Ala Ala Thr Leu Lys Met Lys
                1370                1375                1380

 Gln Gly Pro Met Thr Gln Ala Ile Asn Arg Glu Asn Trp Cys Thr
                1385                1390                1395

 Ile Glu Pro Cys Pro Asp Ala Ala Ser Leu Leu Ala Ser Lys Gln
                1400                1405                1410

 Ser Pro Glu Cys Glu Asn Phe Leu Asp Val Gly Leu Gly Arg Glu
                1415                1420                1425

 Cys Thr Ser Lys Gln Gly Val Leu Lys Arg Glu Ser Gly Ser Asp
                1430                1435                1440

 Ser Asp Leu Phe His Ser Pro Ser Asp Asp Met Asp Ser Ile Ile
                1445                1450                1455

 Phe Pro Lys Pro Glu Glu Glu His Leu Ala Cys Asp Ile Thr Gly
                1460                1465                1470

 Ser Ser Ser Ser Thr Asp Asp Thr Ala Ser Leu Asp Arg His Ser
                1475                1480                1485

 Ser His Gly Ser Asp Val Ser Leu Ser Gln Ile Leu Lys Pro Asn
                1490                1495                1500

 Arg Ser Arg Asp Arg Gln Ser Leu Asp Gly Phe Tyr Ser His Gly
                1505                1510                1515

 Met Gly Ala Glu Gly Arg Glu Ser Glu Ser Glu Pro Ala Asp Pro
                1520                1525                1530

 Gly Asp Val Glu Glu Glu Glu Met Asp Ser Ile Thr Glu Val Pro
                1535                1540                1545

 Ala Asn Cys Ser Val Leu Arg Ser Ser Met Arg Ser Leu Ser Pro
                1550                1555                1560

 Phe Arg Arg His Ser Trp Gly Pro Gly Lys Asn Ala Ala Ser Asp
                1565                1570                1575

 Ala Glu Met Asn His Arg Ser Ser Met Arg Val Leu Gly Asp Val
                1580                1585                1590

 Val Arg Arg Pro Pro Ile His Arg Arg Ser Phe Ser Leu Glu Gly
                1595                1600                1605

 Leu Thr Gly Gly Ala Gly Val Gly Asn Lys Pro Ser Ser Ser Leu
                1610                1615                1620

 Glu Val Ser Ser Ala Asn Ala Glu Glu Leu Arg His Pro Phe Ser
                1625                1630                1635

 Gly Glu Glu Arg Val Asp Ser Leu Val Ser Leu Ser Glu Glu Asp
                1640                1645                1650

 Leu Glu Ser Asp Gln Arg Glu His Arg Met Phe Asp Gln Gln Ile
                1655                1660                1665

 Cys His Arg Ser Lys Gln Gln Gly Phe Asn Tyr Cys Thr Ser Ala
                1670                1675                1680

 Ile Ser Ser Pro Leu Thr Lys Ser Ile Ser Leu Met Thr Ile Ser
                1685                1690                1695

 His Pro Gly Leu Asp Asn Ser Arg Pro Phe His Ser Thr Phe His
                1700                1705                1710

 Asn Thr Ser Ala Asn Leu Thr Glu Ser Ile Thr Glu Glu Asn Tyr
                1715                1720                1725

 Asn Phe Leu Pro His Ser Pro Ser Lys Lys Asp Ser Glu Trp Lys
                1730                1735                1740

 Ser Gly Thr Lys Val Ser Arg Thr Phe Ser Tyr Ile Lys Asn Lys
                1745                1750                1755

 Met Ser Ser Ser Lys Lys Ser Lys Glu Lys Glu Lys Glu Lys Asp
                1760                1765                1770

 Lys Ile Lys Glu Lys Glu Lys Asp Ser Lys Asp Lys Glu Lys Asp
                1775                1780                1785

 Lys Lys Thr Val Asn Gly His Thr Phe Ser Ser Ile Pro Val Val
                1790                1795                1800

 Gly Pro Ile Ser Cys Ser Gln Cys Met Lys Pro Phe Thr Asn Lys
                1805                1810                1815

 Asp Ala Tyr Thr Cys Ala Asn Cys Ser Ala Phe Val His Lys Gly
                1820                1825                1830

 Cys Arg Glu Ser Leu Ala Ser Cys Ala Lys Val Lys Met Lys Gln
                1835                1840                1845

 Pro Lys Gly Ser Leu Gln Ala His Asp Thr Ser Ser Leu Pro Thr
                1850                1855                1860

 Val Ile Met Arg Asn Lys Pro Ser Gln Pro Lys Glu Arg Pro Arg
                1865                1870                1875

 Ser Ala Val Leu Leu Val Asp Glu Thr Ala Thr Thr Pro Ile Phe
                1880                1885                1890

 Ala Asn Arg Arg Ser Gln Gln Ser Val Ser Leu Ser Lys Ser Val
                1895                1900                1905

 Ser Ile Gln Asn Ile Thr Gly Val Gly Asn Asp Glu Asn Met Ser
                1910                1915                1920

 Asn Thr Trp Lys Phe Leu Ser His Ser Thr Asp Ser Leu Asn Lys
                1925                1930                1935

 Ile Ser Lys Val Asn Glu Ser Thr Glu Ser Leu Thr Asp Glu Gly
                1940                1945                1950

 Val Gly Thr Asp Met Asn Glu Gly Gln Leu Leu Gly Asp Phe Glu
                1955                1960                1965

 Ile Glu Ser Lys Gln Leu Glu Ala Glu Ser Trp Ser Arg Ile Ile
                1970                1975                1980

 Asp Ser Lys Phe Leu Lys Gln Gln Lys Lys Asp Val Val Lys Arg
                1985                1990                1995

 Gln Glu Val Ile Tyr Glu Leu Met Gln Thr Glu Phe His His Val
                2000                2005                2010

 Arg Thr Leu Lys Ile Met Ser Gly Val Tyr Ser Gln Gly Met Met
                2015                2020                2025

 Ala Asp Leu Leu Phe Glu Gln Gln Met Val Glu Lys Leu Phe Pro
                2030                2035                2040

 Cys Leu Asp Glu Leu Ile Ser Ile His Ser Gln Phe Phe Gln Arg
                2045                2050                2055

 Ile Leu Glu Arg Lys Lys Glu Ser Leu Val Asp Lys Ser Glu Lys
                2060                2065                2070

 Asn Phe Leu Ile Lys Arg Ile Gly Asp Val Leu Val Asn Gln Phe
                2075                2080                2085

 Ser Gly Glu Asn Ala Glu Arg Leu Lys Lys Thr Tyr Gly Lys Phe
                2090                2095                2100

 Cys Gly Gln His Asn Gln Ser Val Asn Tyr Phe Lys Asp Leu Tyr
                2105                2110                2115

 Ala Lys Asp Lys Arg Phe Gln Ala Phe Val Lys Lys Lys Met Ser
                2120                2125                2130

 Ser Ser Val Val Arg Arg Leu Gly Ile Pro Glu Cys Ile Leu Leu
                2135                2140                2145

 Val Thr Gln Arg Ile Thr Lys Tyr Pro Val Leu Phe Gln Arg Ile
                2150                2155                2160

 Leu Gln Cys Thr Lys Asp Asn Glu Val Glu Gln Glu Asp Leu Ala
                2165                2170                2175

 Gln Ser Leu Ser Leu Val Lys Asp Val Ile Gly Ala Val Asp Ser
                2180                2185                2190

 Lys Val Ala Ser Tyr Glu Lys Lys Val Arg Leu Asn Glu Ile Tyr
                2195                2200                2205

 Thr Lys Thr Asp Ser Lys Ser Ile Met Arg Met Lys Ser Gly Gln
                2210                2215                2220

 Met Phe Ala Lys Glu Asp Leu Lys Arg Lys Lys Leu Val Arg Asp
                2225                2230                2235

 Gly Ser Val Phe Leu Lys Asn Ala Ala Gly Arg Leu Lys Glu Val
                2240                2245                2250

 Gln Ala Val Leu Leu Thr Asp Ile Leu Val Phe Leu Gln Glu Lys
                2255                2260                2265

 Asp Gln Lys Tyr Ile Phe Ala Ser Leu Asp Gln Lys Ser Thr Val
                2270                2275                2280

 Ile Ser Leu Lys Lys Leu Ile Val Arg Glu Val Ala His Glu Glu
                2285                2290                2295

 Lys Gly Leu Phe Leu Ile Ser Met Gly Met Thr Asp Pro Glu Met
                2300                2305                2310

 Val Glu Val His Ala Ser Ser Lys Glu Glu Arg Asn Ser Trp Ile
                2315                2320                2325

 Gln Ile Ile Gln Asp Thr Ile Asn Thr Leu Asn Arg Asp Glu Asp
                2330                2335                2340

 Glu Gly Ile Pro Ser Glu Asn Glu Glu Glu Lys Lys Met Leu Asp
                2345                2350                2355

 Thr Arg Ala Arg Glu Leu Lys Glu Gln Leu His Gln Lys Asp Gln
                2360                2365                2370

 Lys Ile Leu Leu Leu Leu Glu Glu Lys Glu Met Ile Phe Arg Asp
                2375                2380                2385

 Met Ala Glu Cys Ser Thr Pro Leu Pro Glu Asp Cys Ser Pro Thr
                2390                2395                2400

 His Ser Pro Arg Val Leu Phe Arg Ser Asn Thr Glu Glu Ala Leu
                2405                2410                2415

 Lys Gly Gly Pro Leu Met Lys Ser Ala Ile Asn Glu Val Glu Ile
                2420                2425                2430

 Leu Gln Gly Leu Val Ser Gly Asn Leu Gly Gly Thr Leu Gly Pro
                2435                2440                2445

 Thr Val Ser Ser Pro Ile Glu Gln Asp Val Val Gly Pro Val Ser
                2450                2455                2460

 Leu Pro Arg Arg Ala Glu Thr Phe Gly Gly Phe Asp Ser His Gln
                2465                2470                2475

 Met Asn Ala Ser Lys Gly Gly Glu Lys Glu Glu Gly Asp Asp Gly
                2480                2485                2490

 Gln Asp Leu Arg Arg Thr Glu Ser Asp Ser Gly Leu Lys Lys Gly
                2495                2500                2505

 Gly Asn Ala Asn Leu Val Phe Met Leu Lys Arg Asn Ser Glu Gln
                2510                2515                2520

 Val Val Gln Ser Val Val His Leu Tyr Glu Leu Leu Ser Ala Leu
                2525                2530                2535

 Gln Gly Val Val Leu Gln Gln Asp Ser Tyr Ile Glu Asp Gln Lys
                2540                2545                2550

 Leu Val Leu Ser Glu Arg Ala Leu Thr Arg Ser Leu Ser Arg Pro
                2555                2560                2565

 Ser Ser Leu Ile Glu Gln Glu Lys Gln Arg Ser Leu Glu Lys Gln
                2570                2575                2580

 Arg Gln Asp Leu Ala Asn Leu Gln Lys Gln Gln Ala Gln Tyr Leu
                2585                2590                2595

 Glu Glu Lys Arg Arg Arg Glu Arg Glu Trp Glu Ala Arg Glu Arg
                2600                2605                2610

 Glu Leu Arg Glu Arg Glu Ala Leu Leu Ala Gln Arg Glu Glu Glu
                2615                2620                2625

 Val Gln Gln Gly Gln Gln Asp Leu Glu Lys Glu Arg Glu Glu Leu
                2630                2635                2640

 Gln Gln Lys Lys Gly Thr Tyr Gln Tyr Asp Leu Glu Arg Leu Arg
                2645                2650                2655

 Ala Ala Gln Lys Gln Leu Glu Arg Glu Gln Glu His Val Arg Arg
                2660                2665                2670

 Glu Ala Glu Arg Leu Ser Gln Arg Gln Thr Glu Arg Asp Leu Cys
                2675                2680                2685

 Gln Val Ser His Pro His Thr Lys Leu Met Arg Ile Pro Ser Phe
                2690                2695                2700

 Phe Pro Ser Pro Glu Glu Pro Pro Ser Pro Ser Ala Pro Ser Ile
                2705                2710                2715

 Ala Lys Ser Gly Ser Leu Asp Ser Glu Leu Ser Val Ser Pro Lys
                2720                2725                2730

 Arg Asn Ser Ile Ser Arg Thr His Lys Asp Lys Gly Pro Phe His
                2735                2740                2745

 Ile Leu Ser Ser Thr Ser Gln Thr Asn Lys Gly Pro Glu Gly Gln
                2750                2755                2760

 Ser Gln Ala Pro Ala Ser Thr Ser Ala Ser Thr Arg Leu Phe Gly
                2765                2770                2775

 Leu Thr Lys Pro Lys Glu Lys Lys Glu Lys Lys Lys Lys Asn Lys
                2780                2785                2790

 Thr Ser Arg Ser Gln Pro Gly Asp Gly Pro Ala Ser Glu Val Ser
                2795                2800                2805

 Ala Glu Gly Glu Glu Ile Phe Cys
                2810

<210> 4461
<211> 2346
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 308-441, 2200-2281
<223> Unknown base

<400> 4461
 taaccagtgt tcttaatgaa gtatttagtc ttgggtttct tgtaaatttc 50

 tctgcattcc ttagacagtg tactatacat gaaatattct tgttgaccta 100

 gtaatttata ttattccatt taattcttaa acctatggcc tttttattga 150

 gcacactctt aaatcatttg gcttgtaaac attcatctga attgtggcta 200

 caatcctctt taaataatct aggaaaaaag aaagataaag cttacatttt 250

 cacagttttg gctcttaaac acattccaca aatgccatta agaatttatt 300

 tgttttannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngtttttcat 450

 tttttttcat gttatctatc caagcactgt tccatggtca gcaagtcata 500

 tttcataatg tggattttcc aaaataatta ttgaatacag ctattctatg 550

 gctactttta gtgtttttgt ggtatgtggt gtgggagtgt ttatggaatt 600

 accagtatct taaattttca aaggaacctt ggaagtctat cactctaaat 650

 gaaagtctgt cactctacat gaattatgtg ctcaaatttg accaactcag 700

 tttaagacac aaaacagtaa tttgaagaag gaaaaatgaa gagagtttct 750

 agtttaatgg gttaaatttt tgttgttgca atagtaagtt tagtcttctt 800

 ataatatttc taaatgaaaa atcataggta tttgttacca tgtgtgaaga 850

 ttagtttgtt aaaagcaaaa gtggtcgtgt gatatgctaa atgttaatta 900

 ctgattttat atgtttaaat cacgccaaac aaattatgtc tgtgccatcc 950

 agggtctgtt gttaatcttt ttctgagtac ttggattggg ataaagggct 1000

 tgtactatgc actttttatt aatgaataaa tagaaaacgt tagtaacact 1050

 ttgtgttttc tgtttggctt ttgtgtgaag agaagcaagc atcttttgcc 1100

 tagtagatgt taacattgtg tattaaacag tttctttgta agacctaact 1150

 aaagacattc ctaagagaga acttaagttt taagaaaagt tgtgagaaaa 1200

 atattcataa aatatgcagt atggggccag tattcagaag tagagtttct 1250

 ctcttggaaa ttagattgca gtcacatttc tttggttatt ttctttctct 1300

 ctctcttcct agaataccag gtaaaataga catttacttt gagggactaa 1350

 tatccaatag tgttaattat ttaagcagat atatctagct caaaaggaac 1400

 cagacatgtc actgtaccaa aaacacacaa aagtgaaaat ttgcttctgt 1450

 tctgtgacct agaatgtgtc cagacattaa agatcatgaa tactcatata 1500

 catgtaaaaa tagtaacact gctctggcat gattttgacg tcagtgttta 1550

 tgtaataact tcagtgttat atttaaaata gataaatttg tgaaataaca 1600

 atttcttgga gacagtcaac tttttatgat ttaatctaaa gattgtcatg 1650

 tacatgtcaa cggatatctg aatcctcagt gaaactgtta agttttcatt 1700

 aaatgactct gctgcaatac tagttttctt ctcagaaaat ggaattcaaa 1750

 taaaataagt tttttggtct tggcatttca cctgatgact ttctctgttc 1800

 tggatctcaa tttgtagagt tgttgggggt tcccccccct ccaaaaaatg 1850

 ctccataaac accaactaca attatctttc atgatcatat tttaaaaatt 1900

 ggagttacct gtgtgatctt ttcccattag ttgcttgtag gggactttag 1950

 tgtgcgtatc tcttctcaga caaatgtatt atgttcgttc aataaacact 2000

 tcaacaaatt tttatacttg tttcttaact ctctataggc tttaaaatgg 2050

 attttattca ggatttgatt acagaaacta tttcaaacca tcagatgcca 2100

 aattgtctac tgacgttagt gaggagatgt ctgggaggca aggactatgt 2150

 aggggtgaaa acaatatata tagttttaaa gataaagcaa ctttctttcn 2200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nggcttatgt tttacccaaa 2300

 caatacctta ctatgactgg ctctgtgtcc ccacccaaat ctcatc 2346

<210> 4462
<211> 130
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 58-103
<223> unknown amino acid

<220>
<221> Unsure
<222> 308-441, 2200-2281
<223> Unknown amino acid

<400> 4462
 Met Ala Phe Leu Leu Ser Thr Leu Leu Asn His Leu Ala Cys Lys
   1               5                  10                  15

 His Ser Ser Glu Leu Trp Leu Gln Ser Ser Leu Asn Asn Leu Gly
                  20                  25                  30

 Lys Lys Lys Asp Lys Ala Tyr Ile Phe Thr Val Leu Ala Leu Lys
                  35                  40                  45

 His Ile Pro Gln Met Pro Leu Arg Ile Tyr Leu Phe Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Phe Ser
                  95                 100                 105

 Phe Phe Phe Met Leu Ser Ile Gln Ala Leu Phe His Gly Gln Gln
                 110                 115                 120

 Val Ile Phe His Asn Val Asp Phe Pro Lys
                 125                 130

<210> 4463
<211> 2817
<212> DNA
<213> Homo sapien

<400> 4463
 agcggagtgt gagggatttt ggaagcactt gccccaagca gagtttaaaa 50

 tggagatggc aaatgaagca cagaaatctc tttgctctgg aaactggggt 100

 cccaccctgg ggacttcttt gggtgagaag ttgaagagtc gggatagatg 150

 agatgacctt tcacatctgg tatcctcagg tccgagcccc tggacagcag 200

 ccccaggcgc agctggccat ggccctgtgc ctgaagcagg tgttcgccaa 250

 ggacaagacg ttccggccgc ggaagcgctt tgagccgggc acacagcgct 300

 ttgagctgta caagaaggca caggcctctc tcaagtcggg cctggacctg 350

 cgcagtgtgg tgaggctacc acccggggag aacatcgacg actggatcgc 400

 cgtgcacgtg gtggacttct tcaaccgcat caacctcatc tacggcacta 450

 tggcggagcg ctgcagtgag accagctgcc cggtcatggc cggcgggccc 500

 cgctacgagt accgctggca ggacgagcgc cagtaccggc ggcccgccaa 550

 gctctctgcg ccgcgctata tggcgttgct catggactgg atcgaaggcc 600

 tcatcaacga cgaagaggtc tttcccacgc gtgttggagt tcccttccct 650

 aagaacttcc agcaggtctg caccaagatc ctgacccgcc tcttccgagt 700

 ctttgtccat gtctacatcc accacttcga tagcatcctc agcatggggg 750

 cagaggagca cgtcaacacc tgctacaagc acttctacta cttcatccgc 800

 gagttcagtc tggtggacca gcgggagctg gagccactga gggagatgac 850

 agagcggatc tgccactgag cccaggtctg gacttttttg gccatcagat 900

 ggacgatctg aacatagggt ggctggcaga ggggaccccc aggagcctga 950

 aggaatctga aggcactgga atcactccac acacccaaag cctctggact 1000

 tctggttctc aggagtctgc ctacctgtcg ccctgaccgc ttgtggatgg 1050

 agaaggggag agcatctagg caggcaaaca gaagggaagt ggagttaaac 1100

 ctctggcatg aagtctggga gtagggtagg ctagggggtt tcttctatga 1150

 cacttgaccc ttccatgctg gttcccaagc ctattggagg aatgtgggtg 1200

 tggccgaggt gatggcaaga aaggtgcaag aaagtgagca gtctgcctgt 1250

 gagtgagcac agatgccggg gtgtgtgtgt gtgtgtgtga ttttcactgt 1300

 ggggtgtgtc tgtgagagct agctgcctta cccctccttg gcacatagta 1350

 ggccttccat aaatgttgga tggatggata aatagattgg gaccatcaga 1400

 ccatgggacc atcagaccat gtccactgta ggagtgatga cagctcagcg 1450

 tccccactca gtgtatctga ccatgtgtgt aagtgcacaa aaatgtggtt 1500

 gtagatgttg ctctacattc aaaccttcca ggctacactc ttccatcagc 1550

 atgagtcctg gagagctggg ggaaggtagg aagaggagcc ttgccttgag 1600

 ttcctaaacc gacccactgc agacacaggc tctgattctc ttacccagag 1650

 atgcccatga gctgacattt tactcatccc tctgcctcca agaaggcctg 1700

 tattatacgt gtcctcctgg gggttggaga tgatccctca agtacacaaa 1750

 ggtcccctgg cccttcatct gggaatcata tactccactc tagctcccag 1800

 aatctacaga cctggctcct cggatctgaa gcccagcaca aaataatctc 1850

 cccgtccaag gagcttgtgg aacttgaatt gggaactttg gagtcttgtc 1900

 tcccatccca gcacattgag gatgtagttg gtgaatggac tcttccaggc 1950

 atggagatcc tccatcctaa aagtacctgc ctccttccca gccatccctg 2000

 acacattcca gccagttgga tctcacagca cagctatcca cagggagact 2050

 gggatgttca cgcagcactc cattactcag tacctccata cccagcccta 2100

 tacgcagacc cacaggtggg gaaactgagg caggaacagg gttctgccct 2150

 cccagagcct ccactctggg atgccagaat ggaaagccag agggaacctg 2200

 agaatcatcc agtcttactg tctcaatgta catacgggga aactgaagcc 2250

 aggagaagaa gagggagaaa ctgtccaggg cctcacaggg aggcattcat 2300

 ggagctggag aaaccaggga tcctgaccgc agggcccatc aattgctaca 2350

 tagagataca catggaaaga gggtttaaca gaccctctct aggacacaac 2400

 tgtttctgct ttgagcaata atttctaacc tgaggccaac atgtcccact 2450

 gccccttggg ttggctgggg ttgtttcctg agccaagcat ccaatatcat 2500

 gccccactca atggcctaga agctgcctgt actttgggga aacagatgga 2550

 gctcttgggc ccagccagct gggcctggga cttctgcctc tgccgcctcc 2600

 agagtggcct ggcagctttg ccagaggctg tggagcgagg gtaggagctt 2650

 ttcccagagt gctgtgactt gcatgatgga ttctaggctg tggcaagggc 2700

 tgatttctgg gataggggga gggttggaaa atttattttt atgaaacaga 2750

 gggaagactt tattgttgtt atttttggta aaataaaagg caaactaaag 2800

 caaaaaaaaa aaaaaaa 2817

<210> 4464
<211> 216
<212> PRT
<213> Homo sapien

<400> 4464
 Met Ala Leu Cys Leu Lys Gln Val Phe Ala Lys Asp Lys Thr Phe
   1               5                  10                  15

 Arg Pro Arg Lys Arg Phe Glu Pro Gly Thr Gln Arg Phe Glu Leu
                  20                  25                  30

 Tyr Lys Lys Ala Gln Ala Ser Leu Lys Ser Gly Leu Asp Leu Arg
                  35                  40                  45

 Ser Val Val Arg Leu Pro Pro Gly Glu Asn Ile Asp Asp Trp Ile
                  50                  55                  60

 Ala Val His Val Val Asp Phe Phe Asn Arg Ile Asn Leu Ile Tyr
                  65                  70                  75

 Gly Thr Met Ala Glu Arg Cys Ser Glu Thr Ser Cys Pro Val Met
                  80                  85                  90

 Ala Gly Gly Pro Arg Tyr Glu Tyr Arg Trp Gln Asp Glu Arg Gln
                  95                 100                 105

 Tyr Arg Arg Pro Ala Lys Leu Ser Ala Pro Arg Tyr Met Ala Leu
                 110                 115                 120

 Leu Met Asp Trp Ile Glu Gly Leu Ile Asn Asp Glu Glu Val Phe
                 125                 130                 135

 Pro Thr Arg Val Gly Val Pro Phe Pro Lys Asn Phe Gln Gln Val
                 140                 145                 150

 Cys Thr Lys Ile Leu Thr Arg Leu Phe Arg Val Phe Val His Val
                 155                 160                 165

 Tyr Ile His His Phe Asp Ser Ile Leu Ser Met Gly Ala Glu Glu
                 170                 175                 180

 His Val Asn Thr Cys Tyr Lys His Phe Tyr Tyr Phe Ile Arg Glu
                 185                 190                 195

 Phe Ser Leu Val Asp Gln Arg Glu Leu Glu Pro Leu Arg Glu Met
                 200                 205                 210

 Thr Glu Arg Ile Cys His
                 215

<210> 4465
<211> 1567
<212> DNA
<213> Homo sapien

<400> 4465
 cccacgccgg cgggagcgcc cgttcgcgct gccagcagct tccgcctgct 50

 acggtcctgg caagcacctc gggatcccat tccttcacag ggaccctagc 100

 cagttaaagc tgatacattc ctgtgggtca actatgcaac taactcagat 150

 tttgagcaaa caaagctctc aagttggtga tcctcaggag tctctgcatt 200

 agttggacag ctcttctgga attatcttct aagtcaactg tgggttgggt 250

 aggtggctct gctgattttt cgctggactt ccacatttgg gaccagttgg 300

 ctgtcatcag ctctagaaag ggtgtggctg ttttacattg gctgttttcc 350

 tcacattcct caagcaggta ctgtaataaa gaactggaga aatacagtca 400

 gatgggaagt agcccctgct gtcaaggagc ttgccatcta atgggggaga 450

 caggcaagta aaccaaagac tacacagtgc agtatggtaa gtgccatgat 500

 tttgatgtga cagggcacag tggacgacct tccaaatcaa agcaagtaac 550

 taggggttga caatggtaag tatcatagtt gaagtatcct tgaacaaggt 600

 ttcaggaaga agaagaaggg aatttcatgc agggaaacag ccaaagctca 650

 gtgagtcaaa atatcacagc attcttggta agcccaattg ttttttctgt 700

 tttgctattt tggtggagag aaaggaacac ataaaggaat aacatgagag 750

 aaggctattt ggggaagtgt agtagttaag gttctggctc aaacaacaac 800

 tgcagctcat aaagttgact ttagaggaag gatactgggg tatctcatgg 850

 aatcttggga actgttgaat aaccagggaa actctgggaa actcactggt 900

 aggaatccat aaactgtcct cctggtgggc tgtaaacaac tcaccctcta 950

 tgcatctcac atcaaaattc cagtttcttg ggaaaacaag tctgtttgcc 1000

 caatttgggt catatttcca cctccatgtt actcaggcat gattcatctg 1050

 caagttatgt gtatagatat tttgctactg ttccaccctt acgctgtgct 1100

 ggggagggag gtgtcactgt gagctgtgtc ggtgccttaa gagatatctg 1150

 ttgtgtctta ttacttggtt gcttttcccc acatgtacaa tgacaaaaat 1200

 gccttcaacc tatttgatcc agccgttcca gtacaactcc tatacttgcc 1250

 atctttccaa gcccaaaggt acatccagct gatggaagga gcatcttggt 1300

 gttaatattc ttttagtcat ggtctctgaa agtaaaatgt ctattcttct 1350

 aattctggca caatcttatc tagctatagt tcctcatggt cctgcactcc 1400

 atggactaaa ttgtaagtat aattactacc aatgtactct ataaataact 1450

 tttggggcca gggtggcaat agttgctaga gaaaaaaaaa aaaaaaagga 1500

 aaaaaaatct atgtcgggtg cggagaaaga ggtaatgaaa tggcaggaat 1550

 tcgatatcga gcttatc 1567

<210> 4466
<211> 66
<212> PRT
<213> Homo sapien

<400> 4466
 Pro Arg Arg Arg Glu Arg Pro Phe Ala Leu Pro Ala Ala Ser Ala
   1               5                  10                  15

 Cys Tyr Gly Pro Gly Lys His Leu Gly Ile Pro Phe Leu His Arg
                  20                  25                  30

 Asp Pro Ser Gln Leu Lys Leu Ile His Ser Cys Gly Ser Thr Met
                  35                  40                  45

 Gln Leu Thr Gln Ile Leu Ser Lys Gln Ser Ser Gln Val Gly Asp
                  50                  55                  60

 Pro Gln Glu Ser Leu His
                  65

<210> 4467
<211> 5082
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1484-1520
<223> Unknown base

<400> 4467
 tgaacagtga gtgcagctag ttcattgttt gcacaaggaa ctacagtcta 50

 attgcagttc ctattttagc tgatgaaaca accagtttgt catggaaatt 100

 attttagtgt ggtattatgt accagatttt tagaatccat aacttgaaat 150

 tagctttaca cgctacatag taaatagtgg actacagaaa caaaagtatt 200

 aacataagga ccttaatttt tttcacctat tttatgacct taaatattca 250

 gtattttttt aattccatct gtattttcgt tttgtcagtg agtggaataa 300

 tgtgctcctt atttaaaaca tcttttcccc taacagtaga acctattagg 350

 tcttgtggtt tgatcactca ctggttttga gaatagatga gtcatctcta 400

 gtatagatct tcatggtagg ccattcacct tcagtctatt actcatagca 450

 aaaactccac ggactttttt aagtttaaaa cccatgaatc tgcttaggtt 500

 ttataatctc agtatttgac atttgctcac tatttcatct ctatttgttg 550

 gcccggtttt tctgtatttt ctttgcccaa actgctcatt atcaagatga 600

 acatttggga tatactcttt ttgagaccct caagggcata ttgacatgaa 650

 tttagttaat tttagtcatc tattgatgtt gaagaattgt gaagacagtc 700

 actggtagag gtgattctat ggaggctatc ccatcccagt ggaatgttaa 750

 tgctttacca aaatgtgtta gctgcagtag acagatgttt ctgtcttggg 800

 ggtttagggc acaacatttc tgaggaactc tgactcaatc tgtcccttct 850

 cctttcacag ggcagcaagg cgaaccccat ccctactcac tggagctcag 900

 ctttgatttt taacctccct tccccaccct tccagaacac acacattcca 950

 ttccaaaact gattttataa agacatttta aacataatga tgcaacttgg 1000

 tgtgcactac agcaaatgta caggtgtttt tttttttaat tgtttccaaa 1050

 accgggacct ggatttaaga tgtaattttt aaaatttcta tttctatttt 1100

 ttctgcagca gttgggttag aggaggagga gccttttagc ctctcataaa 1150

 ctgacctctc tacttcctcg tgtattttta agattgattg atgatgtgga 1200

 aagggctttg cttgtctgct actgaaaact ttatccttgc ggtttttgtg 1250

 gaaactgctt ttggaaagag aaaagaaatg aactttactg acttgacatt 1300

 tttgcacctc ccgtttttct aatctgggct atttttattt ttgttttttt 1350

 acagtgagat ttttttgatc ttcagctaca gtaagttatt ccaatttttt 1400

 tttaacattt ttcctgactt tccgctgatt tcctttttat tgttgttact 1450

 agttactatt acttattatt attatattaa tacnnnnnnn nnnnnnnnnn 1500

 nnnnnnnnnn nnnnnnnnnn gatttttaac cggattaaaa tcgagttttt 1550

 ctgaatgttt ctaagaattt ctccggcctc ctgattgact ttggagtttt 1600

 gcatcttggg agagaaagcg aaggcattag tatttttaag tggtttgatc 1650

 acgtaaacct tttctctccc aaccccaccc ttgccctcat ccccttcccc 1700

 acactgaaaa gaattttact ggctgttaag tctatgacct tatttttcct 1750

 gatctttaac ttaactgttt tagagcatct ctggacgtct gtatttttaa 1800

 ttttttttat ttttgttttt ttatttttaa tctttcattt gttaaatttt 1850

 taaactgtgc tgcaataaaa tgtgtgtggt actacttaac acttatgatc 1900

 gtgatggcat tttccctgaa agccatcttc ctcctgtttc ccttgaaatc 1950

 ccatcctgct tttcctgtac actacccctc acaaaccaca agctgcagca 2000

 acatggatgc ccagcctgga gcagcagcag ccaggatgac ctggagccag 2050

 gggggccttc ggaacagatg cacacccttc ctgggtgatg ttttcggctt 2100

 tgtgagaaac cttaccatca aacacgatgg ccagcaacgt taccaacaag 2150

 acagatcctc gctccatgaa ctcccgtgta ttcattggga atctcaacac 2200

 tcttgtggtc aagaaatctg atgtggaggc aatcttttcg aagtatggca 2250

 aaattgtggg ctgctctgtt cataagggct ttgccttcgt tcagtatgtt 2300

 aatgagagaa atgcccgggc tgctgtagca ggagaggatg gcagaatgat 2350

 tgctggccag gttttagata ttaacctggc tgcagagcca aaagtgaacc 2400

 gaggaaaagc aggtgtgaaa cgatctgcag cggagatgta cggctcctct 2450

 tttgacttgg actatgactt tcaacgggac tattatgata ggatgtacag 2500

 ttacccagca cgtgtacctc ctcctcctcc tattgctcgg gctgtagtgc 2550

 cctcgaaacg tcagcgtgta tcaggaaaca cttcacgaag gggcaaaagt 2600

 ggcttcaatt ctaagagtgg acagcgggga tcttccaagt ctggaaagtt 2650

 gaaaggagat gaccttcagg ccattaagaa ggagctgacc cagataaaac 2700

 aaaaagtgga ttctctcctg gaaaacctgg aaaaaattga aaaggaacag 2750

 agcaaacaag cagtagagat gaagaatgat aagtcagaag aggagcagag 2800

 cagcagctcc gtgaagaaag atgagactaa tgtgaagatg gagtctgagg 2850

 ggggtgcaga tgactctgct gaggaggggg acctactgga tgatgatgat 2900

 aatgaagatc ggggggatga ccagctggag ttgatcaagg atgatgaaaa 2950

 agaggctgag gaaggagagg atgacagaga cagcgccaat ggcgaggatg 3000

 actcttaagc acatagtggg gtttagaaat cttatcccat tatttcttta 3050

 cctaggcgct tgtctaagat caaatttttc accagatcct ctcccctagt 3100

 atcttcagca catgctcact gttctcccca tccttgtcct tcccatgttc 3150

 attaattcat attgccccgc gcctagtccc attttcactt cctttgacgc 3200

 tcctagtagt tttgttaagt cttaccctgt aatttttgct tttaattttg 3250

 atacctcttt atgacttaac aataaaaagg atgtatggtt tttatcaact 3300

 gtctccaaaa taatctcttg ttatgcaggg agtacagttc ttttcattca 3350

 tacataagtt cagtagttgc ttccctaact gcaaaggcaa tctcatttag 3400

 ttgagtagct cttgaaagca gctttgagtt agaagtatgt gtgttacacc 3450

 ctcacattag tgtgctgtgt ggggcagttc aacacaaatg taacaatgta 3500

 tttttgtgaa tgagagttgg catgtcaaat gcatcctcta gaaaaataat 3550

 tagtgttata gtcttaagat ttgttttcta aagttgatac tgtgggttat 3600

 ttttgtgaac agcctgatgt ttgggacctt ttttcctcaa aataaacaag 3650

 tccttattaa accaggaatt tggagaaaaa aaaaaccctg gttttttatt 3700

 tttgtatttt attattgttt acttcaaact ttgttttaca gcgtcctcca 3750

 caaaacctct agaatgcact agatatattt ttcttggagt cataatcatg 3800

 atgcatacca acacaacact actcaaatta tatttcattg agatgcatgt 3850

 tgcattgagg agtcaacttg acatagagtg gagacttttt caaaatggct 3900

 tttacatcct aatgaaagtt tgggaagtat atcctctctg ccttttcatc 3950

 agtgctttgt ggtccagctg gcaccctttc tgaggtttgt gttttgtgct 4000

 aaatggtttt gtccttaaat aggagaggct caaaaacatc aagatttcag 4050

 gaaaatggcg acagctgcat aatggaaccc ccctgcttct attttgttct 4100

 tttaattact atttatagcc ccagttacct tctgaattct gaagtgtata 4150

 tacctccatg ttcctgaaaa caagaaaact cttacttcct gatattccat 4200

 agactgcctt cccaggtgat tgagaacata gagaatgtta cacatttatt 4250

 ttactctaaa tgatctttta cccctgttag ctaatctttg tgttttcctc 4300

 aactttatta attacagtga ttgcattttt agcatccagt tgtaagatga 4350

 atatattaaa cagctaccag tgttggtgat acctcatcct tgaaaggctt 4400

 agttcatttg tgttttatac ttcagttttt ccagcatagc agaaaatgcc 4450

 gcttataatt tttgtgcaca caaaccttgg attcccctgt aaagttgcta 4500

 ttgtttcata gcatgcggca ctggcctttt ttcatcctac tcattacagg 4550

 caaaactcat gtcttattta tgaggatttt atagatcatt ttctgtaaca 4600

 ggtgacaaaa gcagaaaaga atgaagaggc tgaagtatga actacccttg 4650

 gagcccatat acatgatata ggcaatttct tttgtatgtt aattcagtca 4700

 aaaatactac ccacttgatg ttttctaatc tgatgtgagc tcatgttaca 4750

 cagactttta gtaagtaacc cgtgactaga aaataaactg gatgcttagg 4800

 agagagtgtc agatgtataa gatgctaata aaacctgttt aatattattg 4850

 ttagctgtaa gtttttggga aatactgaac aaattagtcc acaatcaagt 4900

 gtctactttt cccttcactg tagggcctct ccctgcacag agcagtctgt 4950

 ttagctgtga acaccacaat ctgcagatgt tcaagtccct tacataaaat 5000

 ggcatagtat ttatatgtaa cctatgcata ttctcctgta tattttaaat 5050

 catctctaca ttaaaatacc tgataaaatg ta 5082

<210> 4468
<211> 293
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1484-1520
<223> Unknown amino acid

<400> 4468
 Met Ala Ser Asn Val Thr Asn Lys Thr Asp Pro Arg Ser Met Asn
   1               5                  10                  15

 Ser Arg Val Phe Ile Gly Asn Leu Asn Thr Leu Val Val Lys Lys
                  20                  25                  30

 Ser Asp Val Glu Ala Ile Phe Ser Lys Tyr Gly Lys Ile Val Gly
                  35                  40                  45

 Cys Ser Val His Lys Gly Phe Ala Phe Val Gln Tyr Val Asn Glu
                  50                  55                  60

 Arg Asn Ala Arg Ala Ala Val Ala Gly Glu Asp Gly Arg Met Ile
                  65                  70                  75

 Ala Gly Gln Val Leu Asp Ile Asn Leu Ala Ala Glu Pro Lys Val
                  80                  85                  90

 Asn Arg Gly Lys Ala Gly Val Lys Arg Ser Ala Ala Glu Met Tyr
                  95                 100                 105

 Gly Ser Ser Phe Asp Leu Asp Tyr Asp Phe Gln Arg Asp Tyr Tyr
                 110                 115                 120

 Asp Arg Met Tyr Ser Tyr Pro Ala Arg Val Pro Pro Pro Pro Pro
                 125                 130                 135

 Ile Ala Arg Ala Val Val Pro Ser Lys Arg Gln Arg Val Ser Gly
                 140                 145                 150

 Asn Thr Ser Arg Arg Gly Lys Ser Gly Phe Asn Ser Lys Ser Gly
                 155                 160                 165

 Gln Arg Gly Ser Ser Lys Ser Gly Lys Leu Lys Gly Asp Asp Leu
                 170                 175                 180

 Gln Ala Ile Lys Lys Glu Leu Thr Gln Ile Lys Gln Lys Val Asp
                 185                 190                 195

 Ser Leu Leu Glu Asn Leu Glu Lys Ile Glu Lys Glu Gln Ser Lys
                 200                 205                 210

 Gln Ala Val Glu Met Lys Asn Asp Lys Ser Glu Glu Glu Gln Ser
                 215                 220                 225

 Ser Ser Ser Val Lys Lys Asp Glu Thr Asn Val Lys Met Glu Ser
                 230                 235                 240

 Glu Gly Gly Ala Asp Asp Ser Ala Glu Glu Gly Asp Leu Leu Asp
                 245                 250                 255

 Asp Asp Asp Asn Glu Asp Arg Gly Asp Asp Gln Leu Glu Leu Ile
                 260                 265                 270

 Lys Asp Asp Glu Lys Glu Ala Glu Glu Gly Glu Asp Asp Arg Asp
                 275                 280                 285

 Ser Ala Asn Gly Glu Asp Asp Ser
                 290

<210> 4469
<211> 1956
<212> DNA
<213> Homo sapien

<400> 4469
 aatcccaatt tattttctaa ctcttttatt ggatgtattt agaacacagt 50

 atacctatag tatacctatg tgtttattat gtttgtaaat ggtaactgac 100

 atttaattat tagaagtact tacccctgcc ttcctccatt tttattcatg 150

 gctacttgag aaagcaaaag gaaaaaataa tagttatcag tagtgtcact 200

 ggaaagaaga gaggagggac aaaactgagc agcagaattc gtatagacat 250

 ttacgtttaa attctaaaag cccaattgag atgttcaggg agggtttgtt 300

 ttgccctttg gcctcatgaa tgggtttcat gaatgggctt cagtggctta 350

 taaactctgt aaaattctat tctaaatttt gtacatttat tttgttccgg 400

 ttaattccag aagacatttc aaacattttt cttacaccat ataataaaaa 450

 tacttaacta aattgacagt tataaaaata aatcagtgaa atgtacctta 500

 tactttaata aaaaatgttt tcagaaatag ataagtgaaa gctgagtgtt 550

 tctttgatag gttcccctgt actataggag tgataattgc agctattgca 600

 atagtagtaa ttgttaaatg gatactaatg aatagcatag catagtgggt 650

 aagagtttat atagcacagg ctctagaatc agattaagta ggttcaaata 700

 ccagttctgc cagtaactgg ttttagaacc ttggggcaag ttaaagaatg 750

 tctcccagcc tcaagtttcc ctatttgtca acaatggaaa tatggtagct 800

 acctcaaacc tcattacgaa ttcaatgagt taaacttgaa aagacttatt 850

 acagtagctg gcacataaag acttgatagt agtttatatg gatgctatct 900

 catattagca tatatggaat taatagtgta tcactatact ttttttttct 950

 tttttttttt gaatagagat cagtctatca cccaggcgtg gagtgtgcag 1000

 gggtgacatt catagcttca cgttgtaact tcctcccatt actctaccaa 1050

 tccttccgtg cctcagcaat ccagacgggc gtgtgatgtg cagggtgtgc 1100

 accaccacac ccagctacat ttttttgtgg gataaagagc gggggtctca 1150

 ctagtgttgg cccagttcgt ggttctcgag ctccgcggcc tcaagcaatc 1200

 ctcccactgg cctcacaagt gtggggatta cgggtataag ccacggcaca 1250

 cggccttact atgctatcaa ttccatatat ggaaaggtgt tttccctttc 1300

 agagctcttt aaagctctgc agaagattta catgtgttta tagagctaag 1350

 agaaatcagg gcatggaaat tgagtgtgta ataaaaatta aactcttcat 1400

 gttatataat catgcataac ttctatcttc attctctgaa gttgcctaga 1450

 gcaccatcac agctaggaag cttccatcat gaattacctt atttccaaaa 1500

 gcaagtactc aaataattgt ctcaagagag gaaggacaaa actgttacaa 1550

 gctgaaatat ttggggattt gtttgacttg actagggaac cacaagtttt 1600

 catataatgc ctgatttagc cctgtgccta acagtttaaa tcttaatgct 1650

 aatgttaatt gcttcccagt tggttgacct tataagaaaa cactgtgtgg 1700

 tattttaatg tggtaaacat gtgaatgaag gcctgtggct cagttaatca 1750

 ctcccacaac tttgagctgt gagttttact ggtggaagga actttaacag 1800

 gtcttcgctc ttgtcattag atatcaaaga actgaaatta gttggaattg 1850

 taagcagtga atagatgtgt tgttagaatg attccatcac ttatacattg 1900

 tttaaaatgc taataaagta acttgctttg taagaaagaa aaaagaagaa 1950

 aaaatt 1956

<210> 4470
<211> 28
<212> PRT
<213> Homo sapien

<400> 4470
 Ile Pro Ile Tyr Phe Leu Thr Leu Leu Leu Asp Val Phe Arg Thr
   1               5                  10                  15

 Gln Tyr Thr Tyr Ser Ile Pro Met Cys Leu Leu Cys Leu
                  20                  25

<210> 4471
<211> 2108
<212> DNA
<213> Homo sapien

<400> 4471
 caaattttct atttttatgt gactctaggg cataacaaaa cagtgacagt 50

 ttcaagcgtt aattttaatg cttcctacta gctaaatatc atcttaaaat 100

 gattatcaga aaaaaaaaaa tgcccccaaa aacttttggg ggcattattt 150

 ggtactggga ggatatttaa attagatttt tcatagtcta ttgttttgaa 200

 ctatggattc tgttttatgg tggataccta aggtttatat aatagttgct 250

 ggaaaactta aagtagctgg tgagcttcct gttatgtcac tattaaagaa 300

 tgatggctga tgtaactctg cccctgaaat ctacaagggt catgcccaaa 350

 ttaatacagg ttaacctttg tagaggtata tatgttggca ttatttattg 400

 acatttatgc ttcaagcatg tcttatttta tgtaatttta agaaatactc 450

 tatttaactt gtgaaatata cctaaaagca tactagttag ctcttagact 500

 ctcacttagg gagggtaaag aaacatcact gatgccaata tgaagatcta 550

 taaacaaatc ctttgtttag aacttttttc tcttcgtgca cctcacaaca 600

 cacttaccat ggtacatatt tcttaatgcc actaagaaag gcaagatagt 650

 gaacgcagaa ttatttatgt ggtatagtgt ttgttttcct gttttagtgc 700

 ttttgtagct aaaacttact ggaactgcat cacaactaca tttgcagtct 750

 cagtgggagg tggactagcc tgtggttaat tttagagctt aaaagtttat 800

 aagcattaaa aacacataca tgtattagaa tcttgtctaa cccctcacaa 850

 aggatgatgg tgatcagcat gccatctttt gaagattaat tctaaaattg 900

 aggactctgg taggttgttt tatttccttc ccaaccagcc attcatttcc 950

 aattgttctg cctttgaaac tttttgtgaa aattgcctgt accaattgca 1000

 ttggttgcgt tgctctgatt taaatgccaa aaacactaaa tatttgtgta 1050

 gtgctgttaa atgaggtttt tgatatttcc atcaaaatga atataaaatt 1100

 cacttgatgg attttgtagt gatgttttca cagttgaaac aaacatattg 1150

 ctgtgcggtg gacagccact tcacagacat gcagacccat ttctttagag 1200

 atattaggtt taaaacccat tttaatttta ttttgctgaa ggtttggaat 1250

 atataaagta atggattcac aaaatatgat atcttaaaac atgttgaaag 1300

 atttgaaagt ggtgcatttt tacttttaag agcagcaatc tttgaaatta 1350

 gtcaacaatg cagtcttttt taaaagtcag ttttctcaag tagtatgttg 1400

 taacgtaaga tgtaactgat ataactagat tttgactggt aaacttaaag 1450

 tgctttttat atttgaggtt gactttaaaa agccattgag cagtcctcag 1500

 aggttatgga ctctcaagcg actaatggaa tagtgttctg ttgtgaagtc 1550

 tagaactaaa gcaccttgta ttgtctgctt ctaaagtgtc ctatagtttt 1600

 taacttaaag tgtaaagagt aacattttat cttatgtcaa ttaaagttac 1650

 atttttcatt tgttggtgta catgtgctac ctgttttatg gggaatgttt 1700

 aacacgatcc tccaagttgg ttctatgcat aaccattcac caaatactgc 1750

 tgctgtgatt ccttgaagga aatattctgt ggtctgctat gatgcattgc 1800

 catcttgctg cttgacaata ggtttataaa taattagaat tacgtgtttt 1850

 aatagtacct ttgtatatat aacaagatgt aaaattaaag atgaggaatg 1900

 tgtgtaaatg atcattcact gtttttgttt taaaactggt cagtactatg 1950

 aagcttctgt ggtttgtatg atgttttaac tttcacttta aactgcatag 2000

 aataaattaa attgaaaaca gcaaaaaaat ctatgtcggg tgcggagaaa 2050

 gaggtaatga aatggcagga attcgatatc agcttatcat ccgtcagcct 2100

 caggggcc 2108

<210> 4472
<211> 16
<212> PRT
<213> Homo sapien

<400> 4472
 Met Lys Trp Gln Glu Phe Asp Ile Ser Leu Ser Ser Val Ser Leu
   1               5                  10                  15

 Arg


<210> 4473
<211> 1165
<212> DNA
<213> Homo sapien

<400> 4473
 gcctgggtga cagaaccaga ccctgtcttt aaaaagggag ttggtgggga 50

 gaggttctag aatgtcatgt agcaaccagt ttaaggactg ggactcaggg 100

 atccaactcc cacagtttcc ctgtgtgacc ctaggcattt gacttagcct 150

 ttctgagcct caggtttttt gtttctgaag taaaaggatt ggactaggta 200

 atctccaaga tcctaggaac ccaggagaaa gatgagaaaa tgtacaagaa 250

 tgaacactca ggtggaaatg ctgcaatcct gagaagctcc caggatgaat 300

 gaaaggcaca ggacctctta cccctcaccc ctgcccccct caagagctgg 350

 tttctcaaac ctttctctta ggccccttca aagggggaaa actaaaaatt 400

 atacaagtta tagttcaagg actttaaata gattatttat atgattgctc 450

 ataaggatga ggctgtgagg agggaacacc ttatttaatc taatgaaatt 500

 ccataggaaa gaggcctttt gtatattgaa tcaatttatc tgccttctca 550

 gtgcatctgt catattctga aagattctgg gttgatcttt tgcgataacc 600

 tctatggctg tgagtgtgtg tgtgtgtttg tgtatttttt aacattttgt 650

 ataatgattg gaggttggta aaaagtaaca caacagtact tttttaatac 700

 aaacttggtg tggtcttgag ttgtcttcca ttggagagcg tacgtgtgcc 750

 acagattggt gcacctgccg gcatctctag gattgcacca actccctcta 800

 gctcttcttg gtggcctgca ggggcctagg gcgcattcac ttccctctgc 850

 ttgactttac gtggtgttct agcgtcagac atcaggcgat gccgtgcatt 900

 acccaagaca ctggacagct ccggatcttc ccgtctaacc actaatcaag 950

 ttaaaaagag gaaattaacg ctttcttagt agtctctgaa agaaactagt 1000

 tatttgcgta aagatgactt ggtattgtgt tgtttatccc tggggagaag 1050

 ggtacagaag accctcaaac tggatttgct gctgaagtgc ttttaactca 1100

 cctgtgcgga gagcggactt caagagaggg cgtgccggtg ctccggacaa 1150

 aacctgggga atact 1165

<210> 4474
<211> 19
<212> PRT
<213> Homo sapien

<400> 4474
 Ala Trp Val Thr Glu Pro Asp Pro Val Phe Lys Lys Gly Val Gly
   1               5                  10                  15

 Gly Glu Arg Phe


<210> 4475
<211> 2380
<212> DNA
<213> Homo sapien

<400> 4475
 tcggccaccg ctcgcttcaa tatggctgcc cccagggaga gacgaggcta 50

 ccatgaagga gccgagcgca gaccctgagt ccgtcaccca tggatcgcag 100

 cgcggagttc aggaaatgga aggcgcaatg tttgagcaaa gcggacctca 150

 gccggaaggg cagtgttgac gaggatgtgg tagagcttgt gcagtttctg 200

 aacatgcgag atcagttttt caccaccagc tcctgcgctg gccgcatcct 250

 actccttgac cggggtataa atggttttga ggttcagaaa caaaactgtt 300

 gctggctact ggttacacac aaactttgtg taaaagatga tgtgattgta 350

 gctctgaaga aagcaaatgg tgatgccact ttgaaatttg aaccatttgt 400

 tcttcatgtg cagtgtcgac aattgcagga tgcacagatt ctgcattcca 450

 tggcaataga ttctggtttc aggaactctg gcataacggt gggaaagaga 500

 ggaaaaacta tgttggctgt ccggagtaca catggcttag aagttccatt 550

 aagccataag ggaaaactga tggtgacaga ggaatatatt gacttcctgt 600

 taaatgtggc aaatcaaaaa atggaggaaa acaagaaaag aattgagagg 650

 ttttacaact gcctacagca tgctttggaa agggaaacga tgactaactt 700

 acatcccaag atcaaagaga aaaataactc atcatatatt cataagaaaa 750

 aaagaaaccc agaaaaaaca cgtgcccagt gtattactaa agaaagtgat 800

 gaagaacttg aaaatgatga tgatgatgat ctaggaatca atgttaccat 850

 cttccctgaa gattactaag ctttggttct gatgtgtctt ggccgtaatg 900

 tttctagtag gttttataaa gctgctcttc ataagagtat tttagtttgt 950

 tgagtgtatc agccattcat aagccagtaa tgacaagtgc agagcttcaa 1000

 actataactt tgttgcccag aggatgtgca gttgtcatct aagctctcag 1050

 cagtacccgg cttatcctac gacttcacct gaaatgctat agttatccct 1100

 acttttttac cagtttctcc cagaagcacc tgcttaataa atcaaagatg 1150

 tttgaatggt gtcttattct gaaataacct gacctaagac aggtatttag 1200

 attattttgg atacattttg aaaagggata gcataaatat tttaagtaaa 1250

 aagaccttta ttttaaataa tagtggatat tttaatgctg gaaattagca 1300

 ttatagttga tatgccagaa attatatctt tggttgtgat ttaaacttat 1350

 gctataaact aaattaatga tgtaaataca tagttttaaa cattctttta 1400

 gggacatgta acttttaagt atcacttcaa taatacgtat tattatagga 1450

 acaaagattt gggaataatt gattacaggt gaggaagtac tggaattcca 1500

 gttcaaggag ataccatttc atttaggact aaaaggacaa gatacaagtt 1550

 cacatgatgg gaaaaatcag aaaacctctc gcagacaaag ggtatataat 1600

 ggatatgagg catcaaaaag catggtatag tcagtgatgg ggaatagtcc 1650

 agaaaggctg aaacacagca tgtgatgcga gtcaaggtag ttgatgccca 1700

 actgtgaagg gccgttctaa tctagcatgg aggtagacag tgtttcctta 1750

 atatggctgc atatcagaat tacctaggtc aggacgaggc atggagatgc 1800

 tactttaata ggccctgccg cagatcttcc aaaccagaat cttaatcctg 1850

 gagtctagga atctttattt ttcacacaac tcatccaagt ggttctgata 1900

 aaatcagtcc agcactttta gaacccactg ataacagact tattcctgga 1950

 gacagcattt gaggaggaat tgaagatttt tctaatgaaa agaaaaaggg 2000

 tcacatgaac agatgttgca gtgtacctgt gccagggatt tcatgtgtac 2050

 actttatagg agaataagca agagcttagg taagttatag tccttaccat 2100

 tgggtctaag gcagtttcca ggaaagcatg gcaactcgtt cagctatgta 2150

 agttgaactc tgtaccactt gggagggaac attcccctag atgacaatgt 2200

 cagtggcact cgaagttgtg cagtgcacat tcttatctac caacatatac 2250

 agcagtcctt ctgggaagga aatttgggca ggaaagggaa ctcacagtgt 2300

 cggaatgcct ggagcatttc ttctagtctg gtggacagaa tatgaaagta 2350

 tctgcctggc agtgcagtaa atgaaaagag 2380

<210> 4476
<211> 259
<212> PRT
<213> Homo sapien

<400> 4476
 Met Asp Arg Ser Ala Glu Phe Arg Lys Trp Lys Ala Gln Cys Leu
   1               5                  10                  15

 Ser Lys Ala Asp Leu Ser Arg Lys Gly Ser Val Asp Glu Asp Val
                  20                  25                  30

 Val Glu Leu Val Gln Phe Leu Asn Met Arg Asp Gln Phe Phe Thr
                  35                  40                  45

 Thr Ser Ser Cys Ala Gly Arg Ile Leu Leu Leu Asp Arg Gly Ile
                  50                  55                  60

 Asn Gly Phe Glu Val Gln Lys Gln Asn Cys Cys Trp Leu Leu Val
                  65                  70                  75

 Thr His Lys Leu Cys Val Lys Asp Asp Val Ile Val Ala Leu Lys
                  80                  85                  90

 Lys Ala Asn Gly Asp Ala Thr Leu Lys Phe Glu Pro Phe Val Leu
                  95                 100                 105

 His Val Gln Cys Arg Gln Leu Gln Asp Ala Gln Ile Leu His Ser
                 110                 115                 120

 Met Ala Ile Asp Ser Gly Phe Arg Asn Ser Gly Ile Thr Val Gly
                 125                 130                 135

 Lys Arg Gly Lys Thr Met Leu Ala Val Arg Ser Thr His Gly Leu
                 140                 145                 150

 Glu Val Pro Leu Ser His Lys Gly Lys Leu Met Val Thr Glu Glu
                 155                 160                 165

 Tyr Ile Asp Phe Leu Leu Asn Val Ala Asn Gln Lys Met Glu Glu
                 170                 175                 180

 Asn Lys Lys Arg Ile Glu Arg Phe Tyr Asn Cys Leu Gln His Ala
                 185                 190                 195

 Leu Glu Arg Glu Thr Met Thr Asn Leu His Pro Lys Ile Lys Glu
                 200                 205                 210

 Lys Asn Asn Ser Ser Tyr Ile His Lys Lys Lys Arg Asn Pro Glu
                 215                 220                 225

 Lys Thr Arg Ala Gln Cys Ile Thr Lys Glu Ser Asp Glu Glu Leu
                 230                 235                 240

 Glu Asn Asp Asp Asp Asp Asp Leu Gly Ile Asn Val Thr Ile Phe
                 245                 250                 255

 Pro Glu Asp Tyr


<210> 4477
<211> 1036
<212> DNA
<213> Homo sapien

<400> 4477
 ggcacgaggc tatgaccccg agcccgtgga gaagctgagg aaactgcaga 50

 gagctttggt ccgcaacgcc ggctcaggtt ctgagacgca gcttcgcgtc 100

 tcctgggaca gtgtcttgag tgcggagcag acgggtcgct ggtggattgt 150

 ggggtccgcc tggagtgggg ccccgatgat cgacaacagt caccatacgc 200

 acctgcagaa gcagcttgtg gggacggtca gttcaaagat cctagaactc 250

 gcccggaagc agaggatgaa cacagacatc cggagaaaca tattctgcac 300

 aataatgaca agtgaagatt ttttggatgc ttttgaaaag cttctgaagc 350

 ttggacttaa ggatcagcag gagagagaaa tcattcacgt tctcatggat 400

 tgctgccttc aagagaaaac ttacaatccc ttctatgctt tcctggctag 450

 caaattctgt gaatatgaaa ggagatttca gatgactttc cagttcagca 500

 tatgggacaa atttcgggac ttggaaaact tgccagctac gaatttctct 550

 aatttggttc atctggtggc ccacttgttg aagacaaaat cgctttccct 600

 ttccatctta aaggtagttg aattcagtga attggacaaa cccagagtcc 650

 gttttttacg aaaagtatta agtatcctat taatggaaac agaagttgaa 700

 gacctcagtt taattttcac aagagtatct gacaacccaa agctgggggt 750

 gttacgtgag ggtttgaagc ttttcatcag ccacttcttg ctaaagaacg 800

 cacaggccca cagaagcgcc gacgaagcca acgtgctgag agagaaagct 850

 gaccttgcaa cgaagtgtct gcaaggaaaa gcttccctga gaatgtagtc 900

 agggaaggaa ggagggcagg tggccctttg actgtaaaat gtccttggta 950

 aacccaaagg cttattctgt tgcctgcgtg tgaatgtttg gtagagctat 1000

 atcattgtct gttaatgtaa aaaaaaaaaa aaaaaa 1036

<210> 4478
<211> 298
<212> PRT
<213> Homo sapien

<400> 4478
 Ala Arg Gly Tyr Asp Pro Glu Pro Val Glu Lys Leu Arg Lys Leu
   1               5                  10                  15

 Gln Arg Ala Leu Val Arg Asn Ala Gly Ser Gly Ser Glu Thr Gln
                  20                  25                  30

 Leu Arg Val Ser Trp Asp Ser Val Leu Ser Ala Glu Gln Thr Gly
                  35                  40                  45

 Arg Trp Trp Ile Val Gly Ser Ala Trp Ser Gly Ala Pro Met Ile
                  50                  55                  60

 Asp Asn Ser His His Thr His Leu Gln Lys Gln Leu Val Gly Thr
                  65                  70                  75

 Val Ser Ser Lys Ile Leu Glu Leu Ala Arg Lys Gln Arg Met Asn
                  80                  85                  90

 Thr Asp Ile Arg Arg Asn Ile Phe Cys Thr Ile Met Thr Ser Glu
                  95                 100                 105

 Asp Phe Leu Asp Ala Phe Glu Lys Leu Leu Lys Leu Gly Leu Lys
                 110                 115                 120

 Asp Gln Gln Glu Arg Glu Ile Ile His Val Leu Met Asp Cys Cys
                 125                 130                 135

 Leu Gln Glu Lys Thr Tyr Asn Pro Phe Tyr Ala Phe Leu Ala Ser
                 140                 145                 150

 Lys Phe Cys Glu Tyr Glu Arg Arg Phe Gln Met Thr Phe Gln Phe
                 155                 160                 165

 Ser Ile Trp Asp Lys Phe Arg Asp Leu Glu Asn Leu Pro Ala Thr
                 170                 175                 180

 Asn Phe Ser Asn Leu Val His Leu Val Ala His Leu Leu Lys Thr
                 185                 190                 195

 Lys Ser Leu Ser Leu Ser Ile Leu Lys Val Val Glu Phe Ser Glu
                 200                 205                 210

 Leu Asp Lys Pro Arg Val Arg Phe Leu Arg Lys Val Leu Ser Ile
                 215                 220                 225

 Leu Leu Met Glu Thr Glu Val Glu Asp Leu Ser Leu Ile Phe Thr
                 230                 235                 240

 Arg Val Ser Asp Asn Pro Lys Leu Gly Val Leu Arg Glu Gly Leu
                 245                 250                 255

 Lys Leu Phe Ile Ser His Phe Leu Leu Lys Asn Ala Gln Ala His
                 260                 265                 270

 Arg Ser Ala Asp Glu Ala Asn Val Leu Arg Glu Lys Ala Asp Leu
                 275                 280                 285

 Ala Thr Lys Cys Leu Gln Gly Lys Ala Ser Leu Arg Met
                 290                 295

<210> 4479
<211> 3615
<212> DNA
<213> Homo sapien

<400> 4479
 ggcacgaggc cgatatggcg gcgactctgg gcagcgggga gcgctggacg 50

 gaagcttaca ttgacgcagt tagaagaaac aaatacccag aagacacacc 100

 tcctgagagt catgacccct gtggctgctg taactgcatg aaggcacaaa 150

 aggaaaagaa gtctgagaat gagtggactc agacccggca gggtgagggg 200

 aactccacgt acagtgagga acagctgctt ggggtacaaa ggatcaagaa 250

 atgcagaaat tactatgaaa ttctgggagt ttctcgagat gctagtgacg 300

 aagagcttaa gaaagcttac agaaaactcg ccctgaaatt tcaccctgac 350

 aagaactgtg ctcctggagc aacagatgct ttcaaagcaa taggaaatgc 400

 atttgcagtc ctgagcaatc ctgataagag acttcgctat gatgaatacg 450

 gagatgaaca ggtgactttc actgcccctc gagccagacc ttataattat 500

 tacagggatt ttgaagctga catcactcca gaagagctgt tcaacgtctt 550

 ctttggagga cattttccta caggaaatat tcatatgttt tcaaatgtga 600

 cagatgacac ttactattac cgtcgacggc accgacatga gaggacacag 650

 actcagaagg aggaggaaga agagaaacct cagactacat attctgcatt 700

 tattcagcta cttccagttc ttgtgattgt gattatatct gtcattactc 750

 agctgctggc tactaatccc ccatatagtc tgttctataa atcgaccttg 800

 ggctacacca tttctagaga aactcagaac ctgcaggtgc cttactttgt 850

 ggataaaaac tttgacaagg cctacagagg agcttctctg catgacttgg 900

 agaaaacaat agagaaggat tacattgatt atatccagac tagttgttgg 950

 aaggagaaac aacaaaagtc agagctgaca aatttggcag gattatacag 1000

 agatgaacga ttgaaacaga aagcagagtc gctgaaactt gaaaactgtg 1050

 agaaactttc caaactcatt ggcctacgca gaggtggctg agaggataat 1100

 ggtcctacgc agggctgggg ttttgctact tgttcctatt tatgttcctg 1150

 attccatttt ataatacaaa actaggtaat gatgaacact ttactatttg 1200

 ctaacttcgt tggttgggca gagtggcagg agcatgggca cgagagccag 1250

 atgtgtcttc acaggatcct tcctggggag tggctccagg gaccaggagt 1300

 agttcatcta agttaaatta atggcaaggc attggattcc gtctccctgc 1350

 tccatgccta ccctgcctat gtgaatggag ttcagggcat cccagagcag 1400

 atccatgctt tcttccttct tcccttcttc agtgaagtct taagaaccag 1450

 gcattcctag gcttagccaa agcttaatat tagttattta cactgtctac 1500

 caagaattat acctctccct tcattagagt catcatctcc gccaagattt 1550

 agcctttgga acatgttcct gcccagcttt ccattttcta ggggaatatg 1600

 gagaaattta aactattgta gtcaatagtt ttctattatt ccaatctctg 1650

 ctcagttagt agcattagca aactgcctaa tttgagattc ctttatttcc 1700

 ttaaccctct ctcctttaga gagtccagaa attaaaacta ctgagcagca 1750

 tctggaggcg ggggccaggg cgaaggtata atgcaagacc gagcctcatc 1800

 tcctccacga agcctcccta ctccatcata gaacccagag aatgtccctt 1850

 cggtcatttc ccctcagtat catcattggt gtcatcgcac ttaggctgag 1900

 ttcctacatc ccacagaggc agatggtcag acccaggagg aggcattgcc 1950

 agctctccag gctgtttgct caagcctaga gatagaggag acagatcctc 2000

 tctccttgga tatgggggtc tagctttggc cccagcagcc actttgttta 2050

 acccagtatc ctatagtttg tgatttgaga tgatttttca ttcattcaac 2100

 atttattgag tgcctactat aaaagcaggg gctctcacac atattttctt 2150

 acttaaacct cctcacaact ctgaagtaga tgtattatcc ctggttctat 2200

 gaatgagaac attggcccag agaggatgac ccaggtcttg tagtggcaga 2250

 gcaagacggt aggctgagtg tcaagtagaa agtgggagag catcctcatg 2300

 tctcaggtga ttctagccag actggcaaag cagaaccttt cccgaggatg 2350

 cctccgtcct ccccaacccc atgacccctc atcttttctg tggcaatctt 2400

 gcatctgttc aggacaacat ccctgctgct ctttaggaag caggaccctg 2450

 tctaacataa attctgtaca caaaataaga ggtccctcac aggcaggcag 2500

 ccctccactg gtgactagga agaattcagt cactgcctgg gctgtgtggt 2550

 tctgggcctt cctgtggagc tgagctgcct gaattatcat gactctgaac 2600

 ttggaaggat cattaagtga ctgtagccta cactccatgc ttccttcata 2650

 ttggaagaaa agtttctggt agagagtcgg ccgggtgcac tggctcaagc 2700

 ctgtaatccc agcactttgg gaggctgtgg caggtggatc acctgaggtc 2750

 aggagttcaa gaccagcctg gccaacacag tgaaacccca tctctactaa 2800

 taatacaaaa attagccagg tgtggtggca catgcctgta gtcccagcta 2850

 ctcgggaggc tgaggcatga gaatcgctgc aacttgcaag gtggaggtta 2900

 cagtgagctg aaatcacgcc actgcactcc actccatctc aaaaaaaaaa 2950

 agagtctaca ttaaacagat tccaaagtaa agtttcttca tcccaatgca 3000

 tggccatgat ttacacagac gtgcctagca tggctcatca acatctgaac 3050

 ggttgttccc taccatgcct ctgcaggcat tccacagagt caggagatgg 3100

 gttcacaggt aaagattggg ggctttagtg gcttgtaggg gacaactgct 3150

 cagttgcagg gagagggagc atttctagaa atagccagat tttgctgccc 3200

 aactagatct gtcctcctgg ttttaggggg cccttcttga tcccctctga 3250

 gtgactgagg gaggttacat tgtaaaatat gtccatgagc caaacaggct 3300

 tatggaaagt tcttctacac acaaaaaaat caaagctctc ctctccccat 3350

 ccccaaccac tgctagaaaa ttggccataa tgaaactgac ttgacaggtt 3400

 aaaagaccct gtcctagatg cccaggaatc aggtagtcac acattttatg 3450

 gacttcatgg cagcgatgag taatctgtga tgatactaaa tagaagcaat 3500

 aataactaac tccattaaat gtcacgctga ttgtctgttt ttatagcaaa 3550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3600

 aaaaaaaaaa aaaaa 3615

<210> 4480
<211> 358
<212> PRT
<213> Homo sapien

<400> 4480
 Met Ala Ala Thr Leu Gly Ser Gly Glu Arg Trp Thr Glu Ala Tyr
   1               5                  10                  15

 Ile Asp Ala Val Arg Arg Asn Lys Tyr Pro Glu Asp Thr Pro Pro
                  20                  25                  30

 Glu Ser His Asp Pro Cys Gly Cys Cys Asn Cys Met Lys Ala Gln
                  35                  40                  45

 Lys Glu Lys Lys Ser Glu Asn Glu Trp Thr Gln Thr Arg Gln Gly
                  50                  55                  60

 Glu Gly Asn Ser Thr Tyr Ser Glu Glu Gln Leu Leu Gly Val Gln
                  65                  70                  75

 Arg Ile Lys Lys Cys Arg Asn Tyr Tyr Glu Ile Leu Gly Val Ser
                  80                  85                  90

 Arg Asp Ala Ser Asp Glu Glu Leu Lys Lys Ala Tyr Arg Lys Leu
                  95                 100                 105

 Ala Leu Lys Phe His Pro Asp Lys Asn Cys Ala Pro Gly Ala Thr
                 110                 115                 120

 Asp Ala Phe Lys Ala Ile Gly Asn Ala Phe Ala Val Leu Ser Asn
                 125                 130                 135

 Pro Asp Lys Arg Leu Arg Tyr Asp Glu Tyr Gly Asp Glu Gln Val
                 140                 145                 150

 Thr Phe Thr Ala Pro Arg Ala Arg Pro Tyr Asn Tyr Tyr Arg Asp
                 155                 160                 165

 Phe Glu Ala Asp Ile Thr Pro Glu Glu Leu Phe Asn Val Phe Phe
                 170                 175                 180

 Gly Gly His Phe Pro Thr Gly Asn Ile His Met Phe Ser Asn Val
                 185                 190                 195

 Thr Asp Asp Thr Tyr Tyr Tyr Arg Arg Arg His Arg His Glu Arg
                 200                 205                 210

 Thr Gln Thr Gln Lys Glu Glu Glu Glu Glu Lys Pro Gln Thr Thr
                 215                 220                 225

 Tyr Ser Ala Phe Ile Gln Leu Leu Pro Val Leu Val Ile Val Ile
                 230                 235                 240

 Ile Ser Val Ile Thr Gln Leu Leu Ala Thr Asn Pro Pro Tyr Ser
                 245                 250                 255

 Leu Phe Tyr Lys Ser Thr Leu Gly Tyr Thr Ile Ser Arg Glu Thr
                 260                 265                 270

 Gln Asn Leu Gln Val Pro Tyr Phe Val Asp Lys Asn Phe Asp Lys
                 275                 280                 285

 Ala Tyr Arg Gly Ala Ser Leu His Asp Leu Glu Lys Thr Ile Glu
                 290                 295                 300

 Lys Asp Tyr Ile Asp Tyr Ile Gln Thr Ser Cys Trp Lys Glu Lys
                 305                 310                 315

 Gln Gln Lys Ser Glu Leu Thr Asn Leu Ala Gly Leu Tyr Arg Asp
                 320                 325                 330

 Glu Arg Leu Lys Gln Lys Ala Glu Ser Leu Lys Leu Glu Asn Cys
                 335                 340                 345

 Glu Lys Leu Ser Lys Leu Ile Gly Leu Arg Arg Gly Gly
                 350                 355

<210> 4481
<211> 1716
<212> DNA
<213> Homo sapien

<400> 4481
 aagtgcgcat ggggacgcta tagcaattcg tttgctgtcc ttcctctcct 50

 tcgaagatga caaggcctac catcgtttct tcctgccttt gggccgtcag 100

 gcagttggtt gggacccgct ccaaccctcg gttcttcctg caatacagtg 150

 gatacaattt gtcatggcta ctctgagtgt tataggttca agttcactta 200

 ttgcctatgc tgtattccat aatatacaga aatctccaga gataagacca 250

 cttttttatc tgagcttctg tgacctgctc ctgggacttt gctggctcac 300

 ggagacactt ctctatggag cttcagtagc gaataaggac atcatctgct 350

 ataacctaca agcagttgga cagttctgga ggctggaagg tccaagatta 400

 agataatcag cagatctggt gtctggggag acggggtttc gccatgtttg 450

 ccaggctggt cctgaatgcc tgacctcaag tgattcaccg cttgggcctc 500

 ccaaagtgct gggattacag gtgtgagcca ctgcacctgg cctccttaaa 550

 tgtatcttta tggcctaatt ttcacctttg cacccagttg atattctaca 600

 tttcctcatt tctctacacc gtcaattaca tctggtattt gtacacagag 650

 ctgaggatga aacacaccca gagtggacag agcacatctc cactggtgat 700

 agattatact tgtcgagttt gtcaaatggc ctttgttttc tcaagcctga 750

 tacctctgct attgatgaca cctgtattct gtctgggaaa tactagtgaa 800

 tgtttccaaa acttcagtca gagccacaag tgtatcttga tgcactcacc 850

 accatcagcc atggctgaac ttccaccttc tgccaacaca tctgtctgta 900

 gcacacttta tttttatggt atcgccattt tcctgggcag ctttgtactc 950

 agcctcctta ccattatggt cttacttatc cgagcccaga cattgtataa 1000

 gaagtttgtg aagtcaactg gctttctggg gagtgaacag tgggcagtga 1050

 ttcacattgt ggaccaacgg gtgcgcttct acccagtggc cttcttttgc 1100

 tgctggggcc cagctgtcat tctaatgatc ataaagctga ctaagccaca 1150

 ggacaccaag cttcacatgg ccctttatgt tctccaggct ctaacggcaa 1200

 catctcaggg tctactcaac tgtggagtat atggctggac gcagcacaaa 1250

 ttccaccaac taaagcagga ggctcggcgt gatgcagata cccagacacc 1300

 attattatgc tcacagaaga gattctatag caggggctta aattcactgg 1350

 aatccaccct gacttttcct gccagtactt ctaccatttt ttgaagctac 1400

 aatactggaa catccaggaa ctggagttat tctacgctaa tggattggaa 1450

 agaatgttgg gaaaggacat cttaaatctt ttctaactat gccctaaact 1500

 gcagaactca aaggaaatat agtgccattg ttagtagtca ttctagatga 1550

 attgggagta tctctccagt tattcccaga ttcactagtg atccttaaag 1600

 tctctattca gggagaggaa gacactttcc atctcagaga tagactcgtg 1650

 ttaccttgat ggatattgga tttgtctaag tctcttctag aaaaaataaa 1700

 ttctagatta ttattt 1716

<210> 4482
<211> 245
<212> PRT
<213> Homo sapien

<400> 4482
 Met Lys His Thr Gln Ser Gly Gln Ser Thr Ser Pro Leu Val Ile
   1               5                  10                  15

 Asp Tyr Thr Cys Arg Val Cys Gln Met Ala Phe Val Phe Ser Ser
                  20                  25                  30

 Leu Ile Pro Leu Leu Leu Met Thr Pro Val Phe Cys Leu Gly Asn
                  35                  40                  45

 Thr Ser Glu Cys Phe Gln Asn Phe Ser Gln Ser His Lys Cys Ile
                  50                  55                  60

 Leu Met His Ser Pro Pro Ser Ala Met Ala Glu Leu Pro Pro Ser
                  65                  70                  75

 Ala Asn Thr Ser Val Cys Ser Thr Leu Tyr Phe Tyr Gly Ile Ala
                  80                  85                  90

 Ile Phe Leu Gly Ser Phe Val Leu Ser Leu Leu Thr Ile Met Val
                  95                 100                 105

 Leu Leu Ile Arg Ala Gln Thr Leu Tyr Lys Lys Phe Val Lys Ser
                 110                 115                 120

 Thr Gly Phe Leu Gly Ser Glu Gln Trp Ala Val Ile His Ile Val
                 125                 130                 135

 Asp Gln Arg Val Arg Phe Tyr Pro Val Ala Phe Phe Cys Cys Trp
                 140                 145                 150

 Gly Pro Ala Val Ile Leu Met Ile Ile Lys Leu Thr Lys Pro Gln
                 155                 160                 165

 Asp Thr Lys Leu His Met Ala Leu Tyr Val Leu Gln Ala Leu Thr
                 170                 175                 180

 Ala Thr Ser Gln Gly Leu Leu Asn Cys Gly Val Tyr Gly Trp Thr
                 185                 190                 195

 Gln His Lys Phe His Gln Leu Lys Gln Glu Ala Arg Arg Asp Ala
                 200                 205                 210

 Asp Thr Gln Thr Pro Leu Leu Cys Ser Gln Lys Arg Phe Tyr Ser
                 215                 220                 225

 Arg Gly Leu Asn Ser Leu Glu Ser Thr Leu Thr Phe Pro Ala Ser
                 230                 235                 240

 Thr Ser Thr Ile Phe
                 245

<210> 4483
<211> 2048
<212> DNA
<213> Homo sapien

<400> 4483
 aaactacctg tggggtgatc tgggttgcta cagaaactaa cggacactgg 50

 caaggggtca gaggcattca acccaattct acaacacagg caggtggtca 100

 aaacaacttt caaccagaat ctactgatat ggatagatgc tgtcccttat 150

 ggagggacgc agacttcaga actgtgccca tgactgctga ctgccaccac 200

 caaggccctc aggtacacag cctgcctcct gcaggatgat gtgggcagat 250

 ttcagcccta gttaacagaa gagtccccca ggaggtaggg ggcccccatc 300

 actggagaca tgccagcaga gcctctggcc acctaaccag gaggtcttct 350

 gaaatgacta tacgaggtaa agaagtagta ccagatggtc ccaaagttcc 400

 cttttagcct gaaagctttt ctttgtccct ccttagtgaa tctgtgttcc 450

 gagccctact ctaaagttca gtggtcaata caatagtcca ccaagagact 500

 gggaatgatt agaagtgaaa ttggtccctc cttaccaagg aggggcagat 550

 gatctccatt gcacagggcg attagattct ggagctgagg tggggactgc 600

 aggaggccac ctagtctggt aggtttcaac ccaagctgtg tacattagaa 650

 ttcccttggg agcgtgcagg aaatacagat gcccatgcca cattccagac 700

 caactgaagc tgaatctcca gagtagggcc tgtatgttca tataagctcc 750

 acaggtgatc tgcagtacag tgaagatgga agactgcatg tgtacctatt 800

 tgcaataaag atgaagagga cagcaagctc cagacaggag ctgggactca 850

 acccagatct cttaagtcct gcctggtggc tccttaaaag tccagaagtg 900

 ttgccccaag ccctccctca acatctctgg gaaccgcagc tgcagcacga 950

 tgggggttca gtgcccctgt ttgcccctta cccagctgtg gtttattctg 1000

 cttgtatgtc tgcacaggcc ggatgctcgt gttccttgtc ttattctcca 1050

 tttactcagt cactggggct cactcccgtc tgatgcacta gccaagattg 1100

 ccttagtgtg ctccagaaaa gaaggccaaa tcccaggcat tgtcagggca 1150

 gcagagctct acaggatagg cttacctttc ccacctgtgt ggctagcact 1200

 tcacagttta caaattcctc ccacctccac tcagtgacac atgctgttct 1250

 aacacaggtc aggcaggcat tacagtcccc atgttcagaa tcaaagacct 1300

 agcctcagag aagtgaagaa acatcatgcc aaggtcattg actgccaagc 1350

 ggtagaggtg gggttgcatc cagagagctt cccggtatgc ctctgcacaa 1400

 tgccattcct tggccagctc cctccacccc aagggaccca gactgcacac 1450

 ttaacaaaca ggacacaggt gtctttgaac aaactttttt gtattattat 1500

 ttttacatct agaataaatt atttaaatta tttcacagca agggagaggg 1550

 ataggtaatt tttatcagat atttttttaa accatctgtt ttttaaatta 1600

 catttttgtt tatgttcttg agctgatgta gtggaacttg cctagcacat 1650

 tcaggtccca gccagttggc agagcatgct ctcatctcct tattccatac 1700

 cctgggcgtc ccctttctgt tgactcagga actttctgag aatgaggaca 1750

 gcactaggag atgagctttg gcaggtatcc accttaacgc tacaataatt 1800

 gtgcttcctg aaacaaaact tgagattgta tcatagaagg aaacaggaag 1850

 tcagaaatca aatctatgct tttaattgaa accgtgcctg aaacagtttg 1900

 aatgattgtt ttaatgttgt ttctgaaatt ccttgtacct ttgtgaaaaa 1950

 taatgataat aaataaaagt gaaaataaat agatgtggaa tatgcaatgg 2000

 aaataatgta acaaaataat aaacatctgg ccattttact acaaaaaa 2048

<210> 4484
<211> 78
<212> PRT
<213> Homo sapien

<400> 4484
 Thr Thr Cys Gly Val Ile Trp Val Ala Thr Glu Thr Asn Gly His
   1               5                  10                  15

 Trp Gln Gly Val Arg Gly Ile Gln Pro Asn Ser Thr Thr Gln Ala
                  20                  25                  30

 Gly Gly Gln Asn Asn Phe Gln Pro Glu Ser Thr Asp Met Asp Arg
                  35                  40                  45

 Cys Cys Pro Leu Trp Arg Asp Ala Asp Phe Arg Thr Val Pro Met
                  50                  55                  60

 Thr Ala Asp Cys His His Gln Gly Pro Gln Val His Ser Leu Pro
                  65                  70                  75

 Pro Ala Gly


<210> 4485
<211> 1210
<212> DNA
<213> Homo sapien

<400> 4485
 agcggctggt agaccccgcc aagcgcctcg gagcgcgcag gatgcgctgg 50

 gcggccgcca ccctccgtgg caaggcgagg ccccgggggc gggccggggt 100

 caccacgcct gccccaggga accgcacagg cacgtgcgct aagctgcggc 150

 tacccccgca agcaaccttc caagtccttc gtggcaatgg tgcttccgtg 200

 gggaccgtgc tcatgttccg ctgcccctcc aaccaccaga tggtggggtc 250

 tgggctcctc acctgcacct ggaaggggag catcgctgag tggtcttcag 300

 ggtccccagt gtgcaaactg gtgccaccac acgagacctt tggcttcaag 350

 gtggccgtga tcgcctccat tgtgagctgt gccatcatcc tgctcatgtc 400

 catggccttc ctcacctgct gcctcctcaa gtgcgtgaag aagagcaagc 450

 ggcggcgctc caacaggtca gcccagctgt ggtcccagct gaaagatgag 500

 gacttggaga cggtgcaggc cgcatacctt ggcctcaagc acttcaacaa 550

 acccgtgagc gggcccagcc aggcgcacga caaccacagc ttcaccacag 600

 accatggtga gagcaccagc aagctggcca gtgtgacccg cagcgtggac 650

 aaggaccctg ggatccccag agctctaagc ctcagtggct cctccagctc 700

 accccaagcc caggtgatgg tgcacatggc aaaccccaga cagcccctgc 750

 ctgcctctgg gctggccaca ggaatgccac aacagcccgc agcatatgcc 800

 ctagggtgac cacgcagtga ggctggtgcc catgctccac actgggaggc 850

 caggctgacc ccaccagcca gtcagctaca actccacatc aactccacat 900

 gcgcccagct cgagactgat gagtggaatc agcttccagg tgtagggacc 950

 ccttgagggg ccaagctgac atccaaggct gaggacccca gtggggagtg 1000

 ttctgttccg gcatatcctg gccgtaacga tttttatagt tatggactac 1050

 ttgaaaccac tactgagggt aatttactag ctgtggcctc ccactaacta 1100

 gcattccttt aaagagactg ggaaatgttt taagcaaatc tagttttgta 1150

 taataaaata agaaaatagc aataaacttc ttttcagcaa ctacaaaaaa 1200

 aaaaaaaaaa 1210

<210> 4486
<211> 255
<212> PRT
<213> Homo sapien

<400> 4486
 Met Arg Trp Ala Ala Ala Thr Leu Arg Gly Lys Ala Arg Pro Arg
   1               5                  10                  15

 Gly Arg Ala Gly Val Thr Thr Pro Ala Pro Gly Asn Arg Thr Gly
                  20                  25                  30

 Thr Cys Ala Lys Leu Arg Leu Pro Pro Gln Ala Thr Phe Gln Val
                  35                  40                  45

 Leu Arg Gly Asn Gly Ala Ser Val Gly Thr Val Leu Met Phe Arg
                  50                  55                  60

 Cys Pro Ser Asn His Gln Met Val Gly Ser Gly Leu Leu Thr Cys
                  65                  70                  75

 Thr Trp Lys Gly Ser Ile Ala Glu Trp Ser Ser Gly Ser Pro Val
                  80                  85                  90

 Cys Lys Leu Val Pro Pro His Glu Thr Phe Gly Phe Lys Val Ala
                  95                 100                 105

 Val Ile Ala Ser Ile Val Ser Cys Ala Ile Ile Leu Leu Met Ser
                 110                 115                 120

 Met Ala Phe Leu Thr Cys Cys Leu Leu Lys Cys Val Lys Lys Ser
                 125                 130                 135

 Lys Arg Arg Arg Ser Asn Arg Ser Ala Gln Leu Trp Ser Gln Leu
                 140                 145                 150

 Lys Asp Glu Asp Leu Glu Thr Val Gln Ala Ala Tyr Leu Gly Leu
                 155                 160                 165

 Lys His Phe Asn Lys Pro Val Ser Gly Pro Ser Gln Ala His Asp
                 170                 175                 180

 Asn His Ser Phe Thr Thr Asp His Gly Glu Ser Thr Ser Lys Leu
                 185                 190                 195

 Ala Ser Val Thr Arg Ser Val Asp Lys Asp Pro Gly Ile Pro Arg
                 200                 205                 210

 Ala Leu Ser Leu Ser Gly Ser Ser Ser Ser Pro Gln Ala Gln Val
                 215                 220                 225

 Met Val His Met Ala Asn Pro Arg Gln Pro Leu Pro Ala Ser Gly
                 230                 235                 240

 Leu Ala Thr Gly Met Pro Gln Gln Pro Ala Ala Tyr Ala Leu Gly
                 245                 250                 255

<210> 4487
<211> 4257
<212> DNA
<213> Homo sapien

<400> 4487
 ccaactggat ggtttttgat tgaagcctag aacatctgta gagacaaact 50

 ctacccagtc ttttctagac ctcaactatc tccagtgttg ttgtttaatc 100

 gtagccggat cagggagtga gtcttttagg caaatgttgg attatatatc 150

 aaaggaaaag cttagtttca gagaggagga agggaaagag atgtgaggga 200

 agcatttcat caaccagcta cgtccccctt agaaggatca ctgcagcagg 250

 tcaccgagca ggagtccctc tgagcgtccc ttctgtctcg ttctgcccta 300

 gctggcagca tatgaaccag gcatgatgca gcaggagcag tgaatctgga 350

 gtcagccact tggcaccctg gtttcgctga gaacaaactc tgagatcttg 400

 ggtgacttct catcactctg gacctccatt cctgtgaagt gacaggtgtg 450

 gaccctgagg gtgcggtggt gagcacactg tctcctgctg gcattcaccc 500

 cactcatgct ggaaaggaag atccagatcg tacaaaaatg agaaaaagaa 550

 agaataagaa gggtctggtc ccagttctga ctcggccatt cttacagctc 600

 tttctggctt tgagtttgct tgtggaattt cctgggcagt tgtgttaaat 650

 ccgccaggtc acgtgcagac aaagctgtgg ctgcgagagt tggctggcct 700

 cttggaccag aagccatctc catatcctca tgagcgattc catatctcca 750

 ctcagaccct gtggactaca gtgttccgct gtggtggctg ccaagatgcc 800

 ttcttaaact tatgcaagga aaccaaaccc tcccacagtt cccaagcaga 850

 cactggaagc agaggcttct cacccttcct gctttttcac cacaatcacc 900

 ttgagctcgt cccttggact agagtctcca cagttccagt aaaattctgc 950

 ggtgggctga tgagctgctt gcatttctgt gacatttcca gatatgattc 1000

 tcagtgggat tttggaaact ttgattgctc aagctcaccc ttcttaacat 1050

 tctgtaatgg ttacagatga gaatggaaaa cacatatttt atggatgagg 1100

 cgttttggtc tcccctgcag tcgatttcta gaatcaagtt ttagagttcg 1150

 gctgatgcat ctgcctgggg acctcagatg ggaggagtgt gtcagttgta 1200

 ccccgacaga aatgtctctg ggatctgtgg ctggcttgcc ccgggcatct 1250

 ctcctttaag ctcaagtttt gaactctctg cggttttcca cccctgcctt 1300

 ctcagccaca tgctttggcc ttaaacgctc agtcttgtgg agttcaactc 1350

 tgtcaaacga ttggaaaggg catccatttc cagatctttg gcattttccc 1400

 cgcgctgact ctttgatgat ccttcactgt ggccttttca agctcagctg 1450

 ttcctgtgta tttgagacga gggtgaggga atgtggtggc cacaaaagaa 1500

 cagggacttg cagcacaaat gtcacttctg tctccctttt caatggtagc 1550

 acggaggagg aggtgctgcg ttggagggag gggatcctcc aggagctctc 1600

 tggagcccat ctaggaagct agagtgtgtg gcccgccagg agctcaggaa 1650

 ggatacagcc actgtcgcag gggaaagtgt ttgcttcccg tggagccaag 1700

 cgcccaagac tctccgtatc cttcaccctg acagtttaac ttcagcgttt 1750

 ctctgtgcag ttgcggtcac catgggtgag cactgtctgt gcacgtgcca 1800

 gggaggagat ggctgggacc actgcacagg agggcgcagc ctggcgtcgc 1850

 catgaaagtt gtctctgtgc catctctccg gtccttgagg agagcccaga 1900

 aagattttag gacccaggag gtgcttttcc tccagctgtt gccagtgtcc 1950

 ttctgagcct ggattctccg gggatttccg tcgtggtgga tggacttcac 2000

 atcagcagca gttctggtac agaattgtaa tgtgttttca tttctctgta 2050

 ggattcacct ctcaccagcg tctgtcttaa aggtagggcc aatttcatgg 2100

 agcatttttc tgtgtgtgtc cttgttgctt ttgccagaaa aagtggattt 2150

 gacatgcgtg ccccgatgcc accatagccc ctaggccaac aatgtcatgg 2200

 tctaaacacc aaaaagtgat gccccgcatt ccttccctgg atggtaccgt 2250

 ttcttctccg tctctctttg atgattcttt gggaccaaag tcctctcctt 2300

 agtgcgccta cttcctgtgg gcatcatgcc acttggaact tattggaact 2350

 ggcccgggag actctgcagt ctgcgccgtt tgaaaaccct gagaaagaga 2400

 tgccacctca acttgaatca tgacagccca tcgctcagtc tcaccctaaa 2450

 ctcatggagc ttgtttcagc tcctcacttc ttgactgtat ttgtactatg 2500

 ttgaaaaaat atcctgtcca caaagacata agcctaacaa cctagaaaaa 2550

 caacagggta ctactggcat tacagaactt ctttgccttt caaaacaaaa 2600

 gcaaaacaca gtgaacttca ccacggagct gcacagcgtg gggaactcat 2650

 ccatcacttt caaaattaga gtcatttgat ccaagttgga gtcagacaca 2700

 gtatttgagc tgcacggctt ctgggttctc ccaccttatt tgatcatatt 2750

 cgaaagatta tttcctgtgt ttgctttgat ttgttcctca gtacattaaa 2800

 atgatccaca ccttgaacac tgccctctct agaaggttga ttttgatcag 2850

 ccttttgaag atgggtgtcg tttccctaac ttatctcaca gaattttgag 2900

 tgttgtattt ggcaagttct gagatttgcc ttctgtctta tgccaaacac 2950

 ccctttctaa gagctgtccc cgcttagttt tagaagtact aggggttttc 3000

 atacttattt tatagaacac ccatttatat ttatttctgt atatagaact 3050

 aaaaaaaaca gtagtgttaa aaatctttgt tgtggtttga gcatctttgc 3100

 tgcttttgga ttgagatggc gaatcaaggc ttcacttcct ctctcttctg 3150

 tctttagaaa gctgtgatcg tgcgtgcaat tatttgaaag gcaacatagt 3200

 caattaagaa acctgtagtt gttaaggaag aaattgttgg caagatatcc 3250

 atactgccca tatctcgttg gtgcaataat taaatagcaa aggaaatctg 3300

 tattggcaac tattataatt caataattct tttgtttact gcccttttct 3350

 gttcaagaat tttctggaaa ttactccctt tcacatggtt gaactcttaa 3400

 gttgaccagt tctcatagct ctatcactag aatggtttgc agatacccca 3450

 aacatactat gataaaatca aattgtgcta cttttgaccc atgtaattta 3500

 cctaaaagtt gtaattgctg acagagtact gccttgaatt ttggtttaaa 3550

 acctctctag tttcaatgac aagtaacaac tcaaataatt ccatattgtt 3600

 tgaggaagag gccataatcc ttctgaattg ttggcactaa gtaatgggat 3650

 ttggcccagt aagtatgacg gtcgtgtcgc ctaaccaacg cagagcagtg 3700

 ctttttgtgt ggctgaagcg atgtgctgac gaaaaaagga aaattctagg 3750

 acaatcgttg gctaaaaatc accttaggat gaaaaatttg aggcaaattt 3800

 ttttaaatga cagaaaaaga taatcatctc acttgcttga aacaggagcc 3850

 agcatgatct ctggaagcat caactatccc tcgtcgtgat tgttgaaagc 3900

 tctttcactg ttttgcattc tagtttgaat agtttgtatt gaaattggat 3950

 tcctatcttg tgtatgtttt tggtgcgtaa aagggaaaaa ttggtgtcat 4000

 tacttttgaa atttgcagga cgaagggcat gcttttggtt tgctgtaaga 4050

 ttgtattctg tatatatgtt ttcatgtaaa taaatgaaaa tctatatcag 4100

 agttatattt taatttttat tctaaatgaa aaaaaccctt tttacttcaa 4150

 aaaaattgta agccacattg ttaataaagt aaaaataaat tctgaaaaaa 4200

 aatctatgtc gggtgcggag aaagaggtaa tgaaatggca ggaattcgat 4250

 atcagct 4257

<210> 4488
<211> 9
<212> PRT
<213> Homo sapien

<400> 4488
 Met Lys Trp Gln Glu Phe Asp Ile Ser
   1               5

<210> 4489
<211> 3387
<212> DNA
<213> Homo sapien

<400> 4489
 cgccggcctt ggcctcccaa agtgctggga ttacagacct ggccagccta 50

 aacgattttt aaaacaagtt agagattttg ggttagtctt gttttccagg 100

 aataaagtac catttttagt ggccaaggat gtaccagagg gtgtggccct 150

 gtgacatcca gctgggtctg cccagggccc cgctcagcga ccgaggcttt 200

 ctaggattta tgctgccagt tgcagagaaa atggccctga gtgagggcgt 250

 tatgactgcc ccacctgcct cctgtaaccg cgtggctgtg ggattcgggg 300

 ctgggaattc gggttcctgt ggggccagca cacggccctg tgcttctccc 350

 tcaggcggag agagggtggg ggcagccccg tgcgtctcct gctctaggag 400

 ggagggacgg tgggggccgg tgcgccagtg cggtgtctct gctgcaggtg 450

 gctgggctga cgctgctggc tgtcggggtc tactcagcca agaatgcgac 500

 agccgtcact ggccgcttca tcgaggctcg gctggggaag ccgtccctag 550

 tgagggagac gtcccgcatc acggtgctgg aggcgctgcg gcaccccatc 600

 caggtcagcc ggcggctcct cagtcgaccc caggacgtgc tggagggtgt 650

 tgtgcttagt gtaagtcggt gtgcctggga ccggggaggt gcagggaggg 700

 gaccccggag ctgggctggg ctgtggccct tgctagcgct cgtggtggcg 750

 cccaggagct tttgggtcct gagatgcaac tgcttggact gtgccgggga 800

 tagataggct gcccacgagc tgggcggctt cctgaggagc agagtccgca 850

 cccgggcatt cccgcagccc ctgtcaccga ggcttccgtg ggtgcagagt 900

 gtctccccca aacccccgtc ttccccggca gcccagcctg gaagcacggg 950

 tgcgcgacat cgccatagca accaggaaca ccaagaagaa ccggggcctg 1000

 tacaggcaca tcctgctgta tgggccacca ggcaccggga agacgctgtt 1050

 tgccaagaaa ctcgccctgc actcaggcat ggactacgcc atcatgacag 1100

 gcggggacgt ggcccccatg gggcgggaag gcgtgaccgc catgcacaag 1150

 ctctttgact gggccaatac cagccggcgc gggaggagat aagcaaggac 1200

 ctcagagcca cactgaacgc cttcctgtac cacatgggcc aacacagcaa 1250

 caagtgaggg agcccctcgg gtcctgagcc cccgggcagg gctgtgcagc 1300

 cgtcgccctt ggttcccact gagggtccct ggctcacagt gctgggcacc 1350

 agctgtggcc tcagtgtgcc cacctcagat gtcccctggg aacggcccag 1400

 ctcgggacag cacggggtgt cattgaggaa catgcagggg cctcccgggc 1450

 agagctgggg tcagtcctgt cttcacggcc ctgtgcgccg ccgccccagc 1500

 ttgcaggtcc ctctgcccct agatttctgc ggtcctgtgc ctgcaaggga 1550

 ggtggtctga ttgctgccgc ccagaggtcc ccagtagggt gaccggccct 1600

 atgtccaggc tccctcttcc ctcccaaatc ccttaatttt gagttttctt 1650

 ggtctcctgg gcccctccag ccccagtcac gtgtcacacg gaggatcaag 1700

 tcctgctggt cggccgtggc tgactcttca ggcacgttgg gctcctgggt 1750

 cagctgctgc cgttcgacgc tccctggagc cctgactcag gtccttccca 1800

 gagaggcaag gctggggccc tgctgagcct ctgctgaacc cgggcccccg 1850

 aggtcctgct tctggctcgc atggccataa tcttgacagg gactctgggt 1900

 cccgcatccc tgctcccagc acagcggggc tcaggtagca ggagggagtg 1950

 gtgttcccgg cactgcctat caggctgggc gagggtcagc ggggaagtac 2000

 cacacaggga aagaacagag gcccgagaag ccgggcgggg ggcagctggg 2050

 cgtggtgggg caggcaggcg ggtgaccagg gctgtggctg cgttctcccc 2100

 atgtttcctg tgctcacaag ctgccgcttt agattctccc aaaaagtctc 2150

 cccgaggggg ctgaggagcc cccgttgccc tcggggcatc tcagctggca 2200

 gccccagcgt ttccttcccc atccctgtcc tacagattca tgctggtcct 2250

 ggccagcaat ctgcctgagc agttcgactg tgccatcaac agccgcattg 2300

 acgtgatggt ccacttcgac ctgccgcagc aggaggagcg ggagcgcctg 2350

 gtgagactgc attttgacaa ctgtgttctt aagccggcca cagaaggaaa 2400

 acggtgagtg tcccgcctca cccggccccc aatccaggca ccatatggca 2450

 tgggtgtagg ccagctgcct gtcttccggc ctccacctca tggtgtgggg 2500

 tccgcggcct tggctgcctc acttgggaac tccttcccca ggcgcctgaa 2550

 gctggcccag tttgactacg ggaggaagtg ctcggaggtc gctcggctga 2600

 cggagggcat gtcgggccgg gagatcgctc agctggccgt gtcctggcag 2650

 gccacggcat atgcctccaa ggacggggtc ctcactgagg ccatgatgga 2700

 cgcctgtgtg caagatgctg tccagcagta ccgacagaag atgcgctggc 2750

 tgaaggcgga ggggcctggg cgcggggtcg agcaccccct atccggagtc 2800

 caaggcgaga ccctcacctc atggagcctg gccacggacc cctcctaccc 2850

 ctgccttgcc ggcccctgca catttaggat atgctcctgg atggggactg 2900

 ggctgtgccc agggcctctg tcccccagga tgtcttgtgg tggcggtcgg 2950

 ccgttctgcc ccccagggca ccccctgttg taggcactgg ctagggaggg 3000

 gcaggcctcc ttcctgcccc tcgagacact cttgggagat gcattttccg 3050

 tctggctcac agggggaggg tgaggctttg taccccagcc cctgcccagg 3100

 ccactgtgag ggtgggtgct ggctgagccc ctggggcaga aggagtgggg 3150

 caggcggggt ctttgttctc ggctcccaca gcagagccag gtgagggggg 3200

 gcctgccagg actagacaga agtggggcgg cctgaaccct gcttccagcc 3250

 atggccaggg gccacggaac ccggcagggg tgtctgaggc cgccctgtca 3300

 gctggccggt ccaagcctgt ggctggagct ggtgtgtgtt tatctaataa 3350

 agtcccacag gtgcctcgaa aaaaaaaaaa aaaaaaa 3387

<210> 4490
<211> 177
<212> PRT
<213> Homo sapien

<400> 4490
 Met Gly Val Gly Gln Leu Pro Val Phe Arg Pro Pro Pro His Gly
   1               5                  10                  15

 Val Gly Ser Ala Ala Leu Ala Ala Ser Leu Gly Asn Ser Phe Pro
                  20                  25                  30

 Arg Arg Leu Lys Leu Ala Gln Phe Asp Tyr Gly Arg Lys Cys Ser
                  35                  40                  45

 Glu Val Ala Arg Leu Thr Glu Gly Met Ser Gly Arg Glu Ile Ala
                  50                  55                  60

 Gln Leu Ala Val Ser Trp Gln Ala Thr Ala Tyr Ala Ser Lys Asp
                  65                  70                  75

 Gly Val Leu Thr Glu Ala Met Met Asp Ala Cys Val Gln Asp Ala
                  80                  85                  90

 Val Gln Gln Tyr Arg Gln Lys Met Arg Trp Leu Lys Ala Glu Gly
                  95                 100                 105

 Pro Gly Arg Gly Val Glu His Pro Leu Ser Gly Val Gln Gly Glu
                 110                 115                 120

 Thr Leu Thr Ser Trp Ser Leu Ala Thr Asp Pro Ser Tyr Pro Cys
                 125                 130                 135

 Leu Ala Gly Pro Cys Thr Phe Arg Ile Cys Ser Trp Met Gly Thr
                 140                 145                 150

 Gly Leu Cys Pro Gly Pro Leu Ser Pro Arg Met Ser Cys Gly Gly
                 155                 160                 165

 Gly Arg Pro Phe Cys Pro Pro Gly His Pro Leu Leu
                 170                 175

<210> 4491
<211> 6325
<212> DNA
<213> Homo sapien

<400> 4491
 ctgggttgtc agtcagtgag aggaggggga agatggctca ccgggacccg 50

 ttctgctagg aagaagggga gcaggtggtg ctgctactcg ggaggaagca 100

 gagcagcctc cgtcgctgtc gctgagagcc tcacgagtcg aggtcctgca 150

 ggtggagctc cggcagccgc cctgacatta ccagaaacat ctttaccaaa 200

 ttatgccaca aatttgaaag acaagagttc tttagtttca tctctctata 250

 aagttatcca ggagccacaa agtgagttgc tagaacctgt ctgtcaccag 300

 ctctttgaat tctatcgcag tggagagggg cagttgcttc aatttacgct 350

 gcaatttctc ccagaactaa tttggtgcta ccttgcagtc tcagccagca 400

 gaaatgtgca tagcagtgga tgcattgaag ctcttcttct aggggtttac 450

 aatttggaaa tagttgacaa acagggacat accaaagtat tgagttttac 500

 gattccatct ttatccaaac catctgtata ccatgaacct tccagcattg 550

 ggtccatggc tctgactgag agtgcactat cccagcatgg tttgtcaaaa 600

 gtggtataca gtggacctca tcctcaaagg gagatgctga cagcacagaa 650

 tcggtttgaa gtgttgacat tccttttgtt gtgttacaat gctgccttaa 700

 cttacatgcc cagtgtttct cttcagtcac tgtgtcaaat ttgttcaaga 750

 atctgtgttt gtggatatcc tcgacaacat gtaagaaaat ataaaggtat 800

 aagtagcagg ataccagttt cttcaggatt catggtgcaa atgttaacag 850

 ggatttattt tgccttttat aatggagaat gggatctagc tcaaaaagca 900

 ctggatgata ttatatacag agcccagcta gaattatatc cagagccatt 950

 gctggttgct aatgcaataa aggcttcatt gcctcatggt cccatgaaat 1000

 ctaataagga aggtacaagg tgtattcaag ttgaaatcac accaacttcc 1050

 tctcgaatat caagaaatgc agtaaccagc atgtcaataa ggggtcatag 1100

 gtggaaaaga catgagcaac ctgacaacaa taatgatgct actgaattgg 1150

 gcatccttgt cattcctgag attagtgtca caaatgtggc cggagagaga 1200

 accgggaatg gggaaaaagg cagaacacta ggagagattg atgctcagca 1250

 tatacagggt gtgcaggaaa cagccacaga tcctagaact gagagcaaag 1300

 gcttgccaga gatcaggagg caaaaatctg taagaaaaat gatggaggat 1350

 ggaataaact cacctggcag agtgcagttt tagcagagca ctttataact 1400

 gcactccaag gaaatacaga attaacaggt caagaagaac tgatggagat 1450

 atctgaagtt gacgagggat tttattccag ggctgcgtct agtaccagcc 1500

 agtcgggttt atcaaacagt agtcacaatt gtagtaacaa gccaagtata 1550

 ggaaagaacc acagacggtc aggaggaagc aaaactggag gaaaagaaaa 1600

 agaaactaca ggggaatctt gcaaagatca ctttgctcga aaacaaactc 1650

 agagagccca aagtgagaat cttgagcttc tctctttgaa gagacttact 1700

 ttaacaacca gccaatccct acctaagcct agtagccatg gtttggctaa 1750

 gaccgcagcg actgtattta gtaaatcctt tgaacaagtc agtggtgtca 1800

 cagtcccaca taacccgtca tctgctgttg gttgtggggc tgggacagat 1850

 gccaataggt tttccgcttg tagtctccaa gaagaaaagc ttatttacgt 1900

 ttcagaaaga actgaacttc caatggagca tcaatcaggt cagcagagac 1950

 ctcctagtat tagcattact ctgtccacag attaattagt aacatatttt 2000

 tctcccataa cctagtgaac ctggaaatac aactttgctt ctttatgaaa 2050

 gtaccctggg tctttcatcc gtattcctga caggagccct gatgtcttaa 2100

 attctgaagg ctcccctgac tttatgaagg gaagattgtc taggttgcag 2150

 taagttgaaa tatggttttg ttatttcttg attaagattt tttccccttg 2200

 gtttgagtct tttttttccc tcctcttatt tgttattgtt gccctaagat 2250

 tgtcagtgac aataaatttt gacaggttgt ctaatcaagt tggttatgtc 2300

 tcatgtgagg ttgtaaggtg gtttttcttg ttttggtttg gtttggtttt 2350

 ttaatagctc ctattttgat ggctgtgtgt ttggccttca gagtcaaagg 2400

 gagtctgcat gtatgggaac tgttttatag agaatggggc agaggcacaa 2450

 ctccaggaat tctctagctc ctggtcagga agccaatctg aaaacaggca 2500

 tgtggaaaca caaaaatgat gtgtatgaaa agcacctgat gaaaatattt 2550

 gtaagcagat catctttatg attagaacaa tttgctcaaa gccctggaaa 2600

 atgcctggta acccagtgcc tagaatatta tatgattcca ggggatggct 2650

 agaggcattt ctgttgttat ctctgaaaca tttttatatc aaaaatcaga 2700

 ttgctggtag gtgtgttgtt ttgaagtgtt ttatctggat ttagcatgtg 2750

 aagatccctt tcaattatta aggtataata ggctgtaaag ctgatttacc 2800

 ctactgctgg actttggaaa tcctagttag tttggactcc tataattcag 2850

 agcatacgtc attggaagac ttcctggaaa tcagtgtaaa tcttgcaaca 2900

 tagctctcaa gataccactg tataatatgt aattgtttgt ctgcaaatgc 2950

 atttttcatc tataaaatgt catgaaagaa aataaaggta gtgaaatatg 3000

 gacaaaggac atttatatat taactaaagt tgtttatgtt tgtgttctta 3050

 aatttaaaac acgaagaaaa agaaatgtct ttcttgttag tgaacaggcc 3100

 tgttttaaat atcttagtat gatatcaaaa gaataatcaa tttagttacc 3150

 tcccaactaa aaagtaaaaa tgaaaaagac gacatggcag aagttgaaac 3200

 aaacttgtat gtatctgtat gtgacctcta gatggaaata aaagtttgat 3250

 gtttgctagc cgtggtcctt ttggctatgg ttgcggttcc cctgtaaagc 3300

 aaatgtactt aagtcatcat tcagagtgag agagagaaag cacggctgag 3350

 gctgagtcag ttgaccgttg aggaagacct aaggagctgt ccagttcttg 3400

 gctctttttc actgtgactg cacagcggtt tccttcttca tagtcccttg 3450

 ctgtagtcac caagagagca tgctagtgtt ttcctcttgt tcctgcttat 3500

 gcagagctca gatatatgaa aaatttgtat gctttgaagg ctgccaaagc 3550

 atttatactc tggacatagt tttaactgca actgctttgg ctaccagttt 3600

 aaaccgagtt cttcaaaaag catgaactcg ttttcattca ttagccctgt 3650

 ttacaatgtg gattttgaca taaatgaatt tgattttctt ttagctccag 3700

 taacagaatg gaataagatc tattgccata aattgtagtt aagaactgta 3750

 aggcaatcgg gcagtgaaac ttgatattgt attaacttaa taggaaccct 3800

 gtgtacaatt taaaatattt gtaaaatatc actgtgaatt tacagatgtc 3850

 tttttgtcat tctttaacaa tgaatttccc ctgtgcatag ttattaatag 3900

 tattggtatt attaaaaact aatttggcat tttaagattg gcattttaag 3950

 caagttgagg tgcttaggaa acattgtaga ataagtttgg ggaaatgtta 4000

 gctgacagag ctgagagatc agattttcat gttctatcac tgtaatggaa 4050

 cctcatttag acctctctag acctttgcta gctgtgtggt ctgaggacca 4100

 gtaagtagga ttggcattat ctggtatctt gttaaaaatg cagaatttca 4150

 tgccactcta ggtctactaa atcagaattt gcattcttaa caaggttccc 4200

 aagtgatttt tatgagaaga aagtatcaga gtgcaaacaa attactcgtc 4250

 taatatgtag aattcccagt ggtctcacag ccctagatca aatgtgtcag 4300

 acactagatc attataatct tcattggttt tgacagctaa ttaattagtt 4350

 taataatatt gacatatggc ttcttaagta tttgaattct agattgctaa 4400

 tgatccttat ttttgcagta aaaaagtaac actttatatt tttcttgtta 4450

 actataaatg gaatcagagc tgtaaatgcc tgaaatttta agtgtgaaaa 4500

 ggggtgccac ccttttatat actgcacaac aaatttgcat ttgtatattc 4550

 tttttaaaaa atctctgaag acttgctcag tgaaatggtt ctgatttttt 4600

 gcttcaaatg atttgcacta attgattttc tggagagcgg agttacgtta 4650

 acaacaaaat tcttttatag ttcctttgat actatttcaa ataaggatta 4700

 cacattgaaa gtttttatag aaattatgaa aattggataa tcttaactat 4750

 ggtaaccatt actattatcc atactacttt ctccccactg aactttcaaa 4800

 tttgaaaatt ggggtagctt ttgtaggtca ctttcttata aagatgctga 4850

 tggtcacaga tctcctaagt atccagaata atatttttat catgagaagg 4900

 attccacaca aaattggggt cttgcacccc atatttcaga ggatctgaac 4950

 agaaattgtg gcttcattgc acattttaaa tctctataga ttcttgaaat 5000

 cacccaacct ctcacatttg aaaacccaac ggcctggagt attctggtgg 5050

 cactggagcc agcactagct ttttggaatc caagtgggga gagaaacaaa 5100

 aatagacttt tcaagggact gtcccagact acccagggca aatgtcttcc 5150

 cttcccttcc tgaagccaca ggaaagcacc ctggagtcct ttgtatacca 5200

 ctatggaaat ttttaaggca agctctcaag acttgaagag ttggaattct 5250

 cggcatttaa atgatgcctg aagtttgttt tgaaaaagca atatttcatt 5300

 gctcttttca attgtgaagc aactgctcag caaatattac tcattttttt 5350

 aaaaagttga attaaaggga aatatatttt taaaaccaaa atagatcaaa 5400

 atgatcccag ttttaaggga ttttgcctat tttggaagaa taaaactaaa 5450

 atgttaaaac tgttgaatta cagagaacag atgtactctg agacataatt 5500

 ttaaacaaat atttaaaata aggcaggtta acatttgcgt ttaggcacaa 5550

 taaatctgta ttaaagggaa gcacatcaag gaaatatata catgttgaat 5600

 aatgtaactg aaaaatattt tttaaaaacc acttaaaaag aaaaataatt 5650

 tgatgggtac tttaagcatt gtagatagaa attaatgtat aatagtgtcc 5700

 tcccagtctt tgtatgaaaa attaaaactc tctagtcctt taatgagcat 5750

 gaatttatac ttctacattt gttgcttagt aaaattatac tcagtacttt 5800

 gagttattca gatttatgtt taatattgtt aaattcttca tcagagagca 5850

 taaatatatt gtcttctata ctttgtaact tgtgcatatc taaagaaact 5900

 aacaacgaac attttgggag atgtttttgt gtttttttat agtagagttt 5950

 tagagtacat ttgtcttaat aggaagtttt taccataaac ccaagatttt 6000

 atttcacgta ttgttgcttt ctcttatatg gaacttattg tgtacctctt 6050

 acctttattt ctaatcattt agtgatacta atcttttcat agtaaatata 6100

 tttgtttcta attgtattcc tagagtttac attcctaaag aataaacgac 6150

 gactttggct atttttgtgt gttccctacc ttcttaaggc tatggaaata 6200

 aactggagtt tagttttttg aatttttgta tatttgtgta aatgttctcc 6250

 atatgtagta ctttatacaa caagtgttgc ctcttgtttt attgaaataa 6300

 aaactaaaaa aaaaaaaaaa aaaaa 6325

<210> 4492
<211> 660
<212> PRT
<213> Homo sapien

<400> 4492
 Leu Gly Cys Gln Ser Val Arg Gly Gly Gly Arg Trp Leu Thr Gly
   1               5                  10                  15

 Thr Arg Ser Ala Arg Lys Lys Gly Ser Arg Trp Cys Cys Tyr Ser
                  20                  25                  30

 Gly Gly Ser Arg Ala Ala Ser Val Ala Val Ala Glu Ser Leu Thr
                  35                  40                  45

 Ser Arg Gly Pro Ala Gly Gly Ala Pro Ala Ala Ala Leu Thr Leu
                  50                  55                  60

 Pro Glu Thr Ser Leu Pro Asn Tyr Ala Thr Asn Leu Lys Asp Lys
                  65                  70                  75

 Ser Ser Leu Val Ser Ser Leu Tyr Lys Val Ile Gln Glu Pro Gln
                  80                  85                  90

 Ser Glu Leu Leu Glu Pro Val Cys His Gln Leu Phe Glu Phe Tyr
                  95                 100                 105

 Arg Ser Gly Glu Gly Gln Leu Leu Gln Phe Thr Leu Gln Phe Leu
                 110                 115                 120

 Pro Glu Leu Ile Trp Cys Tyr Leu Ala Val Ser Ala Ser Arg Asn
                 125                 130                 135

 Val His Ser Ser Gly Cys Ile Glu Ala Leu Leu Leu Gly Val Tyr
                 140                 145                 150

 Asn Leu Glu Ile Val Asp Lys Gln Gly His Thr Lys Val Leu Ser
                 155                 160                 165

 Phe Thr Ile Pro Ser Leu Ser Lys Pro Ser Val Tyr His Glu Pro
                 170                 175                 180

 Ser Ser Ile Gly Ser Met Ala Leu Thr Glu Ser Ala Leu Ser Gln
                 185                 190                 195

 His Gly Leu Ser Lys Val Val Tyr Ser Gly Pro His Pro Gln Arg
                 200                 205                 210

 Glu Met Leu Thr Ala Gln Asn Arg Phe Glu Val Leu Thr Phe Leu
                 215                 220                 225

 Leu Leu Cys Tyr Asn Ala Ala Leu Thr Tyr Met Pro Ser Val Ser
                 230                 235                 240

 Leu Gln Ser Leu Cys Gln Ile Cys Ser Arg Ile Cys Val Cys Gly
                 245                 250                 255

 Tyr Pro Arg Gln His Val Arg Lys Tyr Lys Gly Ile Ser Ser Arg
                 260                 265                 270

 Ile Pro Val Ser Ser Gly Phe Met Val Gln Met Leu Thr Gly Ile
                 275                 280                 285

 Tyr Phe Ala Phe Tyr Asn Gly Glu Trp Asp Leu Ala Gln Lys Ala
                 290                 295                 300

 Leu Asp Asp Ile Ile Tyr Arg Ala Gln Leu Glu Leu Tyr Pro Glu
                 305                 310                 315

 Pro Leu Leu Val Ala Asn Ala Ile Lys Ala Ser Leu Pro His Gly
                 320                 325                 330

 Pro Met Lys Ser Asn Lys Glu Gly Thr Arg Cys Ile Gln Val Glu
                 335                 340                 345

 Ile Thr Pro Thr Ser Ser Arg Ile Ser Arg Asn Ala Val Thr Ser
                 350                 355                 360

 Met Ser Ile Arg Gly His Arg Trp Lys Arg His Glu Gln Pro Asp
                 365                 370                 375

 Asn Asn Asn Asp Ala Thr Glu Leu Gly Ile Leu Val Ile Pro Glu
                 380                 385                 390

 Ile Ser Val Thr Asn Val Ala Gly Glu Arg Thr Gly Asn Gly Glu
                 395                 400                 405

 Lys Gly Arg Thr Leu Gly Glu Ile Asp Ala Gln His Ile Gln Gly
                 410                 415                 420

 Val Gln Glu Thr Ala Thr Asp Pro Arg Thr Glu Ser Lys Gly Leu
                 425                 430                 435

 Pro Glu Ile Arg Arg Gln Lys Ser Val Arg Lys Met Met Glu Asp
                 440                 445                 450

 Gly Ile Asn Ser Pro Gly Arg Val Gln Phe Ala Glu His Phe Ile
                 455                 460                 465

 Thr Ala Leu Gln Gly Asn Thr Glu Leu Thr Gly Gln Glu Glu Leu
                 470                 475                 480

 Met Glu Ile Ser Glu Val Asp Glu Gly Phe Tyr Ser Arg Ala Ala
                 485                 490                 495

 Ser Ser Thr Ser Gln Ser Gly Leu Ser Asn Ser Ser His Asn Cys
                 500                 505                 510

 Ser Asn Lys Pro Ser Ile Gly Lys Asn His Arg Arg Ser Gly Gly
                 515                 520                 525

 Ser Lys Thr Gly Gly Lys Glu Lys Glu Thr Thr Gly Glu Ser Cys
                 530                 535                 540

 Lys Asp His Phe Ala Arg Lys Gln Thr Gln Arg Ala Gln Ser Glu
                 545                 550                 555

 Asn Leu Glu Leu Leu Ser Leu Lys Arg Leu Thr Leu Thr Thr Ser
                 560                 565                 570

 Gln Ser Leu Pro Lys Pro Ser Ser His Gly Leu Ala Lys Thr Ala
                 575                 580                 585

 Ala Thr Val Phe Ser Lys Ser Phe Glu Gln Val Ser Gly Val Thr
                 590                 595                 600

 Val Pro His Asn Pro Ser Ser Ala Val Gly Cys Gly Ala Gly Thr
                 605                 610                 615

 Asp Ala Asn Arg Phe Ser Ala Cys Ser Leu Gln Glu Glu Lys Leu
                 620                 625                 630

 Ile Tyr Val Ser Glu Arg Thr Glu Leu Pro Met Glu His Gln Ser
                 635                 640                 645

 Gly Gln Gln Arg Pro Pro Ser Ile Ser Ile Thr Leu Ser Thr Asp
                 650                 655                 660

<210> 4493
<211> 2847
<212> DNA
<213> Homo sapien

<400> 4493
 ggaaattttt taacagagag aaacaaatag aaacatcttc aaatcttcct 50

 aagtgaatat ttaaaatgca gaattgctta tcttctgttt ttctgtattc 100

 agacacttat atctgttgta tatattagtt tagacactct cactaatata 150

 cacagtattt aagactctaa atgagatttc ttaagtattt tattttattc 200

 tctgtaaatg gttttgtata atctttaaac atctacactt tgcctttgta 250

 gatatttaag ggaaaccatt tggggttgtc ttgcatgtat atttttgttg 300

 tagataagtg ttgcttagtt atttctgcaa attttggttg aaatgcttac 350

 agactttaat acagtatata ttttcaaaat ataaactttt atatttctgt 400

 gataagttag gatatgcgtt ttaggcaata tttttcatta atatcacttg 450

 ttcttttgaa aaatagcata ctggtttggt gccaattttt tcattagaat 500

 ataatgctct tatattgttg gagagcaggt taatcttttt tcgaagtaat 550

 tgcgtttgaa gtataatttc aaaatgtatt gaatttgtga ataagcctta 600

 ccattaggat cagtaaattt ttcaactttg caactacata agtagtttaa 650

 gatctccccg taaattctca ctgtgtggca gttgatggag tttgtgaaca 700

 gagccttaag cttgttgcaa aaaaatttaa aaagggtaat acgggttgtt 750

 tcctccatgc aacgtaagcc atgctgatgg actgaatgca gtctgtaatt 800

 catggctaat ccgaagagtt tgattgagtt gatggcggca gggaccagat 850

 agacaccttg gtgattgtct ttggccataa gaatagacca aggataggtt 900

 ttccagagac accttcatac tgtaaacatg gtttagacac ggtcataggg 950

 aaggctgctg gtccatcatt tgttctgaac aaatggcatt tcctgctcct 1000

 gaccctggca gttggcccca gattccttgt cgatgacttg gaaacgtcca 1050

 ttctgggtaa ggtcagcact ccctgagaga tgttaacaaa gtttacctat 1100

 gagtcttact gtgtagacaa tctgaagtca attttagtta cacaatcagc 1150

 attcccatgt gtcctcagtg tcttatcaat gaactatgtg tatcaagcca 1200

 tactaaactg gagtttagca ggacaaaggc aaactaaatg tagaacataa 1250

 catatcagct gaatatgtct atccaggact gtttttctag aacataaatc 1300

 atggagctcc ttgacagtgt atccactgtt tttggggttt aataaaacca 1350

 actagaattt agacttaaaa agaaattatt attccttttg gttgtccaca 1400

 taaagtagtc cagggctatc atatggctaa aatcaagtta tttggttcat 1450

 ctctggtatg tatttataaa gtcaacttat cagccattaa gatggagatt 1500

 tgctttaaat ttttgcagtg tgtgtggcag tcagaaaaac ccatatctag 1550

 ttttcaactt cacctctggt gtttttatgg cttaacctta tatcattgat 1600

 ccaacatcta gcctgatgct ggagctctta tttctagcct gatgctggag 1650

 ctcttatatc tagcctgatg ctggagctct tgaagctgac tcttggaagt 1700

 ttggagggtg tagagtttcc catctagtat ttaatttgtc cctgtgccat 1750

 tagtcccagc ttgaagtcat ttgccagtgt cgatgttgac aggattgtga 1800

 caatattgcc tttcataaaa ccgagaacca aagaattcca ttattctaac 1850

 aaagcctgag tttcatagat tgtgggcaca tctagacaga tatgtgcatg 1900

 cttgatggtg cagagaaact gctgacttcc accaacctca tgctccccct 1950

 ggctggccat acagagggat tcgttgtcat attgaaaagg ctctgaaaga 2000

 tgagtttcta attgaagctc actatctcag gttggtgttt ctactgtgta 2050

 gtcccaagcc tgtatccata tcataaaagt ggaggcctgg tactcctcca 2100

 ggttatctgg ccagtgtaga ctcctccatc tgaatatgaa cctccagggt 2150

 aagaattttt cagacatgtc tatactgaac agtaggatcc tgcactttcc 2200

 aaatgtctgc ctccttttgt tcttcattga cccattctaa ttcctgttag 2250

 gtgtgagaag aattgtcttc agttctctct ccattctcat tcatgatgga 2300

 atcattgatc cattgaccag ttgagaaatg attgatgctg aagaagtggt 2350

 attctattgg taaggcttat taccaaactt ccgataatga agcaggctac 2400

 caaaaactta tccagcccac cctaggagtg tttggatttg atcatggatg 2450

 tagcatacac caaaatccac cgagaccttt gcaaaattag gctacttgtt 2500

 ttattttgcc agattatcat gggagagtct ttaactagtt ctgaatattt 2550

 gtaagtctga gtacttcata gaattataaa gaaggtacag ctgacccctt 2600

 ctcaccatgt tgtaaatatt tactgagact gggtgcagta ctgagggata 2650

 ataatcttct gatttatcaa atcctgactg tctagagcaa attgtacact 2700

 ctctttgtga atggtcctgt aacgtgtatg aacacatttc tgggtgcctt 2750

 agaagttgta tttttcatgt gtgctaatat gcagtattta tacattgtga 2800

 gaagctgctt tgaataaaaa ggttgaaact taaaaaacaa aaaaagg 2847

<210> 4494
<211> 17
<212> PRT
<213> Homo sapien

<400> 4494
 Lys Phe Phe Asn Arg Glu Lys Gln Ile Glu Thr Ser Ser Asn Leu
   1               5                  10                  15

 Pro Lys


<210> 4495
<211> 549
<212> DNA
<213> Homo sapien

<400> 4495
 agtgacctcg ggcggcgggt cacgtcggcc gggcatggct gcatggagcc 50

 cggccgcggc agcgcctctc ctccgcggga tccgcgggct tccacttcac 100

 catcggatgt ttgccactca gactgagggg gagctcagag tgacccaaat 150

 tctcaaagaa aagtttccac gagctacagc tataaaagtc actgacattt 200

 caggaggttg tggggcgatg tatgaaatta aaattgaata agaagaattt 250

 aaggagaaga gaactgtcca gcagcaccag atggttaatc aggcactaaa 300

 agaagaaatc aaagagatgc atggattgcg gatatttacc tctgtcccca 350

 aacgctgacc acgccctggc tgcatagatg ctgctgctta agaccttgga 400

 tgaacttcac tgacatcatt cttccctaag cagtcaccaa aaaatttata 450

 tattttgctc atatacattt ccatattata attatagaag atgtataatc 500

 tatttagatg ttaattaaag gaaacaaaca actgaaaaaa aaaaaaaaa 549

<210> 4496
<211> 68
<212> PRT
<213> Homo sapien

<400> 4496
 Met Ala Ala Trp Ser Pro Ala Ala Ala Ala Pro Leu Leu Arg Gly
   1               5                  10                  15

 Ile Arg Gly Leu Pro Leu His His Arg Met Phe Ala Thr Gln Thr
                  20                  25                  30

 Glu Gly Glu Leu Arg Val Thr Gln Ile Leu Lys Glu Lys Phe Pro
                  35                  40                  45

 Arg Ala Thr Ala Ile Lys Val Thr Asp Ile Ser Gly Gly Cys Gly
                  50                  55                  60

 Ala Met Tyr Glu Ile Lys Ile Glu
                  65

<210> 4497
<211> 4444
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2267-2591
<223> Unknown base

<400> 4497
 attctattct tcattcaggt cccccagaga aattggctcc ttatttttct 50

 ttacctattc ctagacttcc ttttgtctag agccagtttt gcaaagggca 100

 cttttatcca tctcagttat tcccagaggt gacagaatga gtaaaccata 150

 tggggcaaat agcatatatg agctaaacca gttaactgtt aaccaaggca 200

 catggtcaat gccttagtat tttttttttt aattctccta acgttatttc 250

 tagctgtaca ttcccaaaag gaatgggtgg aagcaaatca gattctgaaa 300

 ggtttcaatg atctttcaag tttaggatga gaccaagtct caaggagctg 350

 ggatcttctt tctcttgtca gttgctgaag ccagtagctt cgtcaaaaac 400

 atatgaattc atataaggaa gccctttaga tggtacattc actaagacgt 450

 gtctgggtgt gatcctgttt gggaaaaaca gaatcctagg ttctaaacaa 500

 gaaaagaacg cccttcccaa agggtccgca cactttctgc tttgcagcgg 550

 atcaagtgtc cttgtgaggg tgagacttcc ttcaagggaa gggaagccat 600

 tgctctctct gtagatagag cccagctggt aacgggggag ccacccaact 650

 gcaggggggt gtatgttcag gtgtgaaaaa cagaaaactg ggtctgaaca 700

 tgaagagttg cacagcagta gttcgaagaa gctggcatct ctttggcaaa 750

 caccaacctc agcaaatgca actcctacac ttcattccca aggaccaggt 800

 gttgctcctt aaggaactct gtatccctct ctcctctcca gaaccccatt 850

 cctcccactg gctgagcttt tcctttcctt tccgggtcac ccatagaccc 900

 tctccgtctg taccagtgcg tctgtgttgt gagcgtgacg aagcctttcc 950

 tgtgaagagc tttcatgaac tcattctcat actccttccc catttccacc 1000

 catggggtga ctgttttgct attcaagact atctgtaaaa atgtacaaat 1050

 aaaagtgaaa actgaaaata aaggggaggg agattgagat taaacaaatg 1100

 caatgatgta gcccttagtt ttctgaggac ttctgtggac ggccctaaaa 1150

 tcctgagtta gggtgggatc tgaagggagg gataccattg acacaggagg 1200

 tttttttctg gttgtttctc tcacagtcat cagtgtctgc ttagaactct 1250

 ctgttctaaa ggtttttccc tgtaaagtag aatgcacttc ccccaaaata 1300

 aaagtaaatc agcaatgttt gaagggtcat ggcaagggtc atgacaaaga 1350

 cctgactctg gggtggcatg agtggccctg tcaccggctc actcagggcc 1400

 ttgggggagt ctcattacct caccttgtct ccacgtcttc tcagccaaat 1450

 ggggatcagg ggcttccagg gctctggggg tgcgcagtcc ccttgtgtat 1500

 tttgctgcta tttctagaga gactttgagc ccttgctagt gcgtgcttac 1550

 tgcatggagg taaattagga gatgttttct ctctgctact cctggcctct 1600

 gctttcgccc ctcagaaagt gaccttgagc tagcagccag tttgcactca 1650

 gagtccagag ccttctatct accgtttcat tctcagattc cttttcccac 1700

 ccactttgac gatctcattt tactatcagt ctctactgac tgagctttgc 1750

 tgcactgggc tggggtagga gaaagagcat ccaaggagat gatgtgtgaa 1800

 ttgctttgta atttatgact caccatataa atgtggcttg cagtgtcaga 1850

 agcagggagt ctggccaagg gttgctacca aataagactg aagatggtgg 1900

 aggcagtggt ggcgtggagg cagtaggcag aagatgtggg ttgggagcag 1950

 aggtaagatg aacggagctt tgggaaggac agatggcaga agcaccagaa 2000

 aatcctcagc aaggcagcag agaaggatcc tcaaagcagt aaccctgaag 2050

 taataggaag taggaaagag gagcagggat taggtaaatc tgcagcataa 2100

 acagctgtct ccctgcagga ctgagaagac cagctgcccc agagagggga 2150

 ggcacgtcga gcttggccag tgacccaacc catgattaga ggcaccttca 2200

 atcccaactt tcctctcctc tgctgggtca cagtgatgga accagcttca 2250

 ggaaggtagt atagacnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nacttaggtt 2600

 cttcattagg agactgatgg ggggggtcct tcctggtggg tcactcactg 2650

 ccatagctct tgtcatagct gatgaaggca ggagtgagtc ttattatgtt 2700

 ggcctagagt agaaagcaca gagctatgtc gaggctgctg tctcagcctc 2750

 tggaagttct gcttcacctg cttagtaaga ggagatgacc actcctgtgg 2800

 actgcatgtc ccatctgccc ccagagggtg tcggcgctgc cccagtcatg 2850

 tcccttatga cctgtccaag tcctagaggc caaagcaggt catattcttc 2900

 agctgcagga atgtcagcta ctgcctccca ccccttaacc tgatcccctt 2950

 atcatatagt ggggaagggg caggcaggcc ttctctctgt caagaacaaa 3000

 gatctctaca acatttcgtc acctgggcca gtcacctgct aatatcatct 3050

 caccaatatt tggagctgtt ttctgaatcc cttaattttc ttaaatattt 3100

 atcttaaagt caaatgctat aaaggagata ccctgggaag ggcagtggcc 3150

 acaggcagac tgggtctcct aggaggtggt ggtgttggtg acaagttcta 3200

 cttggactgg gactcaaccc accattgcct acctctcttc cctgcctgga 3250

 gaccttcctt aggattgaag aaacctcttt tgtttgtgaa aaagataggt 3300

 atcgagatct taatggagag aacagaataa aatgcaagga gccaacccct 3350

 gggtattctc aaagcatttc aacggtcagt ataacaaggt ttgattgatt 3400

 taaaatataa cattctgagc cctgtgttac tgagcaaaaa tgagctgatt 3450

 tggtgagtat gttttatata tggtcattag acagggacca taactgacaa 3500

 aactctcaaa cgcctggagt gtttatggcc caccagatta ttgctcagtc 3550

 aatataaatt tatttacctt tattttaatt tgcatagtgc tttctgattg 3600

 gtcagacaag gagtggtgtg tactgcagga ttctaacaat gcctctgccc 3650

 ttggaggcag caattcctgt ggttattggt gctaaaataa gataaaatat 3700

 tatgttaatt tgttctgata tgatgtgaat aaatgtgttg tttaatctta 3750

 acaagaatgc tacatcttat cagatctatt gtactgtctg ttccttctca 3800

 taattaatta attacaggaa aggcgattca aaccagatct tgaaactatt 3850

 gtgatgttct gagaggtaaa tttaacaggg aagtgggagg ggggatgaaa 3900

 agggaaattg ccaggttcct gtgactttga aaggactgag gaagcagaga 3950

 gcatttgggg acttcactga aactgactgc atcttgcaat tttctttttc 4000

 gaattggcag aaatattgta tttccatcga ttgaagaaaa acaagtgtct 4050

 ggtaattaat taaatgactt gtttaatctt aacaagaatg ctacatctta 4100

 tcagatctat tgtactgtct gttccttctc ataattaatt aattacagga 4150

 aaggcgattc aaaccagatc ttgaaactat tgtgatgttc tgagaggtaa 4200

 atttaacagg gaagtgggag gggggatgaa aagggaaatt gccaggttcc 4250

 tgtgactttg aaaggactga ggaagcagag agcatttggg gacttcactg 4300

 aaactgactg catcttgcaa ttttcttttt cgaattggca gaaatattgt 4350

 atttccatcg attgaagaaa aacaagtgtc tggtaattaa ttacaatgac 4400

 ttgttcatgg acaaaaataa ataatctgtc agttgtggaa tgta 4444

<210> 4498
<211> 112
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2267-2591
<223> Unknown amino acid

<400> 4498
 Met Lys Ser Cys Thr Ala Val Val Arg Arg Ser Trp His Leu Phe
   1               5                  10                  15

 Gly Lys His Gln Pro Gln Gln Met Gln Leu Leu His Phe Ile Pro
                  20                  25                  30

 Lys Asp Gln Val Leu Leu Leu Lys Glu Leu Cys Ile Pro Leu Ser
                  35                  40                  45

 Ser Pro Glu Pro His Ser Ser His Trp Leu Ser Phe Ser Phe Pro
                  50                  55                  60

 Phe Arg Val Thr His Arg Pro Ser Pro Ser Val Pro Val Arg Leu
                  65                  70                  75

 Cys Cys Glu Arg Asp Glu Ala Phe Pro Val Lys Ser Phe His Glu
                  80                  85                  90

 Leu Ile Leu Ile Leu Leu Pro His Phe His Pro Trp Gly Asp Cys
                  95                 100                 105

 Phe Ala Ile Gln Asp Tyr Leu
                 110

<210> 4499
<211> 1268
<212> DNA
<213> Homo sapien

<400> 4499
 gtgagcggca acatggcgtc caggtctaag cggcgtgccg tggaaagtgg 50

 ggttccgcag ccgccggatc ccccagtcca gcgcgacgag gaagaggaaa 100

 aagaagtcga aaatgaggat gaagacgatg atgacagtga caaggaaaag 150

 gatgaagagg acgaggtcat tgacgaggaa gtgaatattg aatttgaagc 200

 ttattcccta tcagataatg attatgacgg aattaagaaa ttactgcagc 250

 agctttttct aaaggctcct gtgaacactg cagaactaac agatctctta 300

 attcaacaga accatattgg gagtgtgatt aagcaaacgg atgtttcaga 350

 agacagcaat gatgatatgg atgaagatga ggtttttggt ttcataagcc 400

 ttttaaattt aactgaaaga aagggtaccc agtgtgttga acaaattcaa 450

 gagttggttc tacgcttctg tgagaagaac tgtgaaaaga gcatggttga 500

 acagctggac aagtttttaa atgacaccac caagcctgtg ggccttctcc 550

 taagtgaaag attcattaat gtccctccac agatcgctct gcccatgtac 600

 cagcagcttc agaaagaact ggcgggggca cacagaacca ataagccatg 650

 tgggaagtgc tacttttacc ttctgattag taagacattt gtggaagcag 700

 gaaaaaacaa ttccaaaaag aaacctagca acaaaaagaa agctgcgtta 750

 atgtttgcaa atgcagagga agaatttttc tatgagaagg caattctcaa 800

 gttcaactac tcagtgcagg aggagagcga cacttgtctg ggaggcaaat 850

 ggtcttttga tgacgtacca atgacgccct tgcgaactgt gatgttaatt 900

 ccaggcgaca agatgaacga aatcatggat aaactgaaag aatatctatc 950

 tgtctaaccc atttccaatg gacagtgatg ggcttgtttt tgtaaaatta 1000

 ccagaaaact cagtggagat ttactgaaaa actcagactt tattcagatt 1050

 aagttcctct acaaaaagta gggttctgtc ccatgtgtct ctgacacatt 1100

 tacaaaatac cagtttttta aaattttggt caaattatga gtggttgatt 1150

 taaaaacttt tccaagaaga agaaaagcat ggagtcgtaa tttaaagaac 1200

 tcaataaaaa cttctatttt ttattttaaa ataataccaa aaaaaaaaaa 1250

 aaaaaaaaaa aaaaaaaa 1268

<210> 4500
<211> 314
<212> PRT
<213> Homo sapien

<400> 4500
 Met Ala Ser Arg Ser Lys Arg Arg Ala Val Glu Ser Gly Val Pro
   1               5                  10                  15

 Gln Pro Pro Asp Pro Pro Val Gln Arg Asp Glu Glu Glu Glu Lys
                  20                  25                  30

 Glu Val Glu Asn Glu Asp Glu Asp Asp Asp Asp Ser Asp Lys Glu
                  35                  40                  45

 Lys Asp Glu Glu Asp Glu Val Ile Asp Glu Glu Val Asn Ile Glu
                  50                  55                  60

 Phe Glu Ala Tyr Ser Leu Ser Asp Asn Asp Tyr Asp Gly Ile Lys
                  65                  70                  75

 Lys Leu Leu Gln Gln Leu Phe Leu Lys Ala Pro Val Asn Thr Ala
                  80                  85                  90

 Glu Leu Thr Asp Leu Leu Ile Gln Gln Asn His Ile Gly Ser Val
                  95                 100                 105

 Ile Lys Gln Thr Asp Val Ser Glu Asp Ser Asn Asp Asp Met Asp
                 110                 115                 120

 Glu Asp Glu Val Phe Gly Phe Ile Ser Leu Leu Asn Leu Thr Glu
                 125                 130                 135

 Arg Lys Gly Thr Gln Cys Val Glu Gln Ile Gln Glu Leu Val Leu
                 140                 145                 150

 Arg Phe Cys Glu Lys Asn Cys Glu Lys Ser Met Val Glu Gln Leu
                 155                 160                 165

 Asp Lys Phe Leu Asn Asp Thr Thr Lys Pro Val Gly Leu Leu Leu
                 170                 175                 180

 Ser Glu Arg Phe Ile Asn Val Pro Pro Gln Ile Ala Leu Pro Met
                 185                 190                 195

 Tyr Gln Gln Leu Gln Lys Glu Leu Ala Gly Ala His Arg Thr Asn
                 200                 205                 210

 Lys Pro Cys Gly Lys Cys Tyr Phe Tyr Leu Leu Ile Ser Lys Thr
                 215                 220                 225

 Phe Val Glu Ala Gly Lys Asn Asn Ser Lys Lys Lys Pro Ser Asn
                 230                 235                 240

 Lys Lys Lys Ala Ala Leu Met Phe Ala Asn Ala Glu Glu Glu Phe
                 245                 250                 255

 Phe Tyr Glu Lys Ala Ile Leu Lys Phe Asn Tyr Ser Val Gln Glu
                 260                 265                 270

 Glu Ser Asp Thr Cys Leu Gly Gly Lys Trp Ser Phe Asp Asp Val
                 275                 280                 285

 Pro Met Thr Pro Leu Arg Thr Val Met Leu Ile Pro Gly Asp Lys
                 290                 295                 300

 Met Asn Glu Ile Met Asp Lys Leu Lys Glu Tyr Leu Ser Val
                 305                 310

<210> 4501
<211> 2150
<212> DNA
<213> Homo sapien

<400> 4501
 ttgttctcct cacagcaggt tcaggagaag tggcacctgg tggaggacct 50

 gtcgcgactg ctgccggagc caggcccgag cgactctccg ggccccaagt 100

 accctgcctc ccaagcttcg cgcccgcagt ccttctgccc cggatgccca 150

 tgccctggct ccccgggcca ccaggccccg cggccgggcc cctccgtcgt 200

 ggatgccgcg ggactgcgtt ccccttgccc tggacagcac ggtgccccgg 250

 cctccgcccg cagattccgc ttccccagcg gcgcggagct gtaaccccga 300

 cccctgcctc cccgaagcct ccctggggcc ccttcaggcc tccttactcc 350

 atcttccaga cccctggcga ccaccgcccc tctcagtggc tccagggcct 400

 ccctcagagg tccccaaaga tggacacaca accccagggg cagcaggaaa 450

 aacatatggg aattttcttt ctatatttta atctcatccc tttaaaatgt 500

 ctatttttta ttgtgttttt tataatatac ataatctatt agtatagtat 550

 ctcttgaatg cgattttttc tagaatgtgt tctgctgatt tgttttagag 600

 ccatgagtgc aatttataca catacatcta ttgggaatgc tcagaagttg 650

 tttactgatg gaagtgcctt cagaagagtc cgggaaccac ttcctaagga 700

 aggaaagagc tggccacagt tagagcaagc ctgcctgggg ccctgctctg 750

 tgttccagct gcaaactgcc tgcatcatcc cttcctgtta ctcttccttc 800

 acctgagaca gtcgaggcca cagcgtcagc cagggccaga gctgggattt 850

 gaacccaggc actcgggctc cagagccaca ctgccccagt gtggggctta 900

 gtggcggctc ctggccctga ctgaggggct gactgaagcc tggtgagagc 950

 gtgctgggtc agcctctccc tggcgggaat cctctccgtc cagtcttcta 1000

 acctagcagc ctcacgtcca cagagctgcc ttgtgaaact cagcagagcc 1050

 ctggcttcct gcagagccgt gttctcccag cctgcttcat ggctccctgg 1100

 ttgagccaag cttgcggatc cgtggggtga aggtacccgc accgcctggg 1150

 ccttagtggt atgtacgggc ctgcatcgtg agcagcgggc gggggcccag 1200

 gcaggtgagg cagctggcca caagggcagg gcccggcccc cctcccaagg 1250

 ctgtgtctca tattcttgag cctgttcgag tttccttttc caagcctcct 1300

 gttctcccac ccccacccct gccatgctgc agtgactaaa tctgtggttc 1350

 tcatccttgg agaacacctg agtagctgct acaagctggc cacagcccag 1400

 cgactctgat gtggttgggc tgggtgtggc cagcagccag ggcatcggga 1450

 cttttcgaag ctcccaggtg actcaccggc agctggggat gagaactgtc 1500

 aggagggaag gtcagaagtc ccaggatgca cttgaaaagc ctctagctcc 1550

 accagtgacc agctcctggc tggactcctg gtctggactc agcatcaggg 1600

 aggctctggc ctctcgccct cagggctggg ggcttcttca catggtcatc 1650

 aaagacttgg ccagttccgc ctctcccgcg gccgtccttg tctcacccag 1700

 catcacgacg catcagttca ccaacaaaca cgattcagtg ctgctagtgc 1750

 tgggtcctgt tctgggggct ggtgatgagg ccaagaggga aagagggagc 1800

 tctgtgttcc atcgaggggg cgacaagcct ggaccagatg aaagtgactc 1850

 atgttgttaa ttagcggctt agggccaaag gtggcccctg gaccagtggc 1900

 ctcagcatca cctgggaaaa ggttagaaat gaacattccc aggccccacc 1950

 tcagcctcct gaatcagagc atccctttgg caaaccatac tgagaaacaa 2000

 ccacgtgcat caccaagcgc tgtgaagaag gcaagctttg agaccttgaa 2050

 ggaatcatca aactctgggc ctcggtgtgc tcacccaggg cgagacaaag 2100

 acgccatgct cctccaagtg gcctccaaga ttaaatgagc aatgactttt 2150

<210> 4502
<211> 132
<212> PRT
<213> Homo sapien

<400> 4502
 Met Pro Met Pro Trp Leu Pro Gly Pro Pro Gly Pro Ala Ala Gly
   1               5                  10                  15

 Pro Leu Arg Arg Gly Cys Arg Gly Thr Ala Phe Pro Leu Pro Trp
                  20                  25                  30

 Thr Ala Arg Cys Pro Gly Leu Arg Pro Gln Ile Pro Leu Pro Gln
                  35                  40                  45

 Arg Arg Gly Ala Val Thr Pro Thr Pro Ala Ser Pro Lys Pro Pro
                  50                  55                  60

 Trp Gly Pro Phe Arg Pro Pro Tyr Ser Ile Phe Gln Thr Pro Gly
                  65                  70                  75

 Asp His Arg Pro Ser Gln Trp Leu Gln Gly Leu Pro Gln Arg Ser
                  80                  85                  90

 Pro Lys Met Asp Thr Gln Pro Gln Gly Gln Gln Glu Lys His Met
                  95                 100                 105

 Gly Ile Phe Phe Leu Tyr Phe Asn Leu Ile Pro Leu Lys Cys Leu
                 110                 115                 120

 Phe Phe Ile Val Phe Phe Ile Ile Tyr Ile Ile Tyr
                 125                 130

<210> 4503
<211> 3106
<212> DNA
<213> Homo sapien

<400> 4503
 ctgctgttca caggacatgc cattatgtct ttccagtacg gatcacagtg 50

 ctgccatatc acagaccctg ccagccggca cagaaccatg cctcgtcaca 100

 gctctgccca actcacaggc tgccaagatg aggccacagg tccacctagg 150

 gcggcagatg ctggtgctat ttgtcacgac ttttgccaaa acatgtacac 200

 tgttgctcac atctttcgta agaatggttg acactaaggg gccatggaaa 250

 agcactttta aaaaattatg tggtggaatc aaactcacag aggcagaaat 300

 gttagtgccg tgctctaacc aagtaagctt agtgttcccc acagtgatct 350

 gtatctggcc tgagtctcct caagcagcaa cccccactgt ccagcatgtg 400

 gaaggtagat ccttatgaca acaccagacc catagttacc aggaaagaaa 450

 aaggaagctg agtgttgtga aggggaagaa atccttttta taagaagtaa 500

 tcatttttag gccgggtgca gtggctcatg cctgtaatcc cagcactttg 550

 ggaggctgag acaggtggat cacttgaggt caggagtttg agacctgcct 600

 ggccaacatg atgaaaccct gtctctacta aaaatgcaaa aaaaattagc 650

 caggcatggt ggcatgtgcc tgtagtccca actactcagg aggctgaggc 700

 aggagaatca cttgaacctg ggaggcagag gttgcaatga gctgagatcg 750

 caacactgca ctccagcctg ggcgacagag caagactcca tctcaaaaac 800

 aaaaacaaaa aaaaaacctt tttaaagtaa attgagtgta aaatgttttc 850

 accatgaagc cattgcaccc tctcccccag gaaacagtgc ctaaggatga 900

 tgtcaagtta cagccagttt gctctgatcc cccaggacct aagaaaactg 950

 tgagtgcttc agcatgcaaa ggtagagcta ccagataagg agaataactt 1000

 ggccatttat agcaaactgc ctgactttgg agtgagaaac caagcacctt 1050

 ctaggtccta ggataggtga attggaggtg cagctgctga agttcccatt 1100

 ttctacatac ttcaggagcc agggtgtttc atttggtttt gtaaaacttt 1150

 gctgtaagtc atcacagtta attcttcgaa tggacatttt agagtgtaac 1200

 tttttttcaa aattagcaga acagatatct ctgctcattc tctttataca 1250

 tttagttttt taaagttccc ctagtatacc tgttaggcac tctaaatagg 1300

 acacagttaa agctaaaaga aggaccagtt gctccctaga gcctacagtt 1350

 cagaactatc ttgttgtcat gtcctggttt ggtttggttt gtttttaact 1400

 caacaagttg gaaaccatga gtttaaagca aactatttcc ttttcttaag 1450

 cttaaagaga attttttttt aatctttagc tcctcattta ggtagtgaag 1500

 gcttccctga aagacagcag tgcccttctc tggaagaaga ggctgggacc 1550

 aaaagcctga gtctatgggt tgaggatttt gagcattcct ttgacaagct 1600

 tctatgtatt tttaatataa gactcataaa tgaacctgat gtggtgttca 1650

 tgacccatcc cttaagcatg cttgcttttt ttactttact ttttgagtat 1700

 agtacttgtc ttgtttttcc tggagccatg ctaggattta attcctatgt 1750

 gccactaccc gcccatgtcc tggaagatgg ccatgcctgc agcaatgctc 1800

 atgtcttgag gagaagcaat gtgaaaagca tcaggaaagc tgaaccttac 1850

 gttcaagtca gcaaacattt gtgagcattc tagtatgctt gcgaccttga 1900

 cactttttaa aaattatctt tttatttgct tcgagtatca accgtatagt 1950

 tgactctagt ggggcgaagg gagcagagat gagagcaaaa ttcagacttg 2000

 ctgcccctgt gtgtctcagt tctcatgtct ctctgagaaa tgtgttggcc 2050

 caattcccta tctgccactc tgagtctctt gagtaaatgt gtgtaaatga 2100

 gaaaaattat ctcaaagatt taacttatta tttagatatt ttcttctttt 2150

 taaactcagg aataaacctg gtttgtagat aatataatat ggctactaga 2200

 gctataattg agtaggtgac tagaagcatt ttttcaaata tatttcttgt 2250

 aaagacatct actttgtttt aactaggaaa agaaactcct catattaaaa 2300

 taaacatttc cataagcact ttctagaaga gtgtagcatc catctaccat 2350

 ccatcccaga atgtttgtat cttgctcata gtatttcaaa aatttttatg 2400

 ggtgaaaaaa atgcactttt ttatttattg gaaaagtgta gagttattga 2450

 attaaattct caagtgggac aatttagtgt aaagggaaac atgggttttg 2500

 gagacaagag cacagggctg tggtccctgt tccagcattg actttactat 2550

 gtgacctcga gcaaatgatt taacttctct gtgcctcagt ttctccatat 2600

 acaaaatggg gataatgata ctaaccattg cctacctcat agagatgtta 2650

 tggggacaaa cgaaataata gagataagca cgaatgcttt caactcttcg 2700

 gaagaaaggt gctatataaa ttgaagttgt gtttttaatg atccaattat 2750

 taattatgtt tagggtttaa ataacaatac tgttagtcat gttaagaata 2800

 agttttgttt tgatgcatat ttccacttct cttctgtggc cagatcttga 2850

 tcattcaacc agtaatggta cctgaggaac tgaaatgggt atttgttttc 2900

 gtatgtttct gccagtagta tttcaattga atatccagaa aagactggag 2950

 tttaacttgt aatatcttat agtttacatg taataaaact tattcaagct 3000

 atatataaaa gtatgattac atgtaaatag caggtatgtt gtaattaaag 3050

 gcacttatca aattgtcttt gttctttttt aattgtaata aaagtcagtt 3100

 ttacat 3106

<210> 4504
<211> 133
<212> PRT
<213> Homo sapien

<400> 4504
 Met Pro Leu Cys Leu Ser Ser Thr Asp His Ser Ala Ala Ile Ser
   1               5                  10                  15

 Gln Thr Leu Pro Ala Gly Thr Glu Pro Cys Leu Val Thr Ala Leu
                  20                  25                  30

 Pro Asn Ser Gln Ala Ala Lys Met Arg Pro Gln Val His Leu Gly
                  35                  40                  45

 Arg Gln Met Leu Val Leu Phe Val Thr Thr Phe Ala Lys Thr Cys
                  50                  55                  60

 Thr Leu Leu Leu Thr Ser Phe Val Arg Met Val Asp Thr Lys Gly
                  65                  70                  75

 Pro Trp Lys Ser Thr Phe Lys Lys Leu Cys Gly Gly Ile Lys Leu
                  80                  85                  90

 Thr Glu Ala Glu Met Leu Val Pro Cys Ser Asn Gln Val Ser Leu
                  95                 100                 105

 Val Phe Pro Thr Val Ile Cys Ile Trp Pro Glu Ser Pro Gln Ala
                 110                 115                 120

 Ala Thr Pro Thr Val Gln His Val Glu Gly Arg Ser Leu
                 125                 130

<210> 4505
<211> 1495
<212> DNA
<213> Homo sapien

<400> 4505
 ggggtgtcta gaggatccca atcagtttga acaagaattc acccaacttt 50

 caagatgcct tttcaaaagg atcttgtagt cagttggtat gtacagacaa 100

 ttggcatgga agtggtagga tataaatcgg atgacgcctg gctgctgagg 150

 tgccagctgg atcagctggt gcacttcttg tttcttgtaa gaggtttctt 200

 taaaatgact agtttgatgt atctggtaac atataggcct gactatacat 250

 tttacattat ttcgctattt tgtaaactgg gattttagaa agcacgtttg 300

 ccattttgtt aaagtacatt gccccttaaa ttttggagta gtttttaaaa 350

 gtttaaaatg gtaatagagg agccagaaac tttttaagca ttgtaaaatg 400

 ttttgaattg atattgactt tgtttggaag agagtagagg cagggggctt 450

 taaagaaaca aagaaatgca ttgtaaaaat gtagttttag agcaaattaa 500

 taatgatggt ggggaaagtg ttgctaattt gtttatttcc ctggaagaaa 550

 tgggaagtgt gataagcagt ttaattttta aggagctggt ctcaatttta 600

 gtacttttta attatgcaaa taaatcaatg tttccttaaa ttttgtcatt 650

 gctttgtcac agttgtctag ggttcatatc caaccttctg tggcaattca 700

 attttatata gtcttttaag aggtaattgt aatgtatttc tgacagtata 750

 aacaaaaaga atataaggca tagaagaatt gtcctctaaa aatatcaatg 800

 atgtatcctg gaatgtgaag atgtcccttt atagttaaaa attgaattat 850

 tttaatattg taccattgtt agaccttgaa tgagtccatg ttaccgtgtg 900

 tgtctgtata tctatctgta gagaaagaaa aatgacaact gaaatgttac 950

 ttttaaaaat cagaataaat tgggcactgt ctgtgttgca ccactactgt 1000

 atcttttcga aagaattaac agtatttgcc tattgtaaag gttaattctg 1050

 atgacgtttt cacattcacc agactttttt tcctgtatta tttgcatccc 1100

 caaatattta atacaagtag attctgcatg gcttgggcat tcagagatta 1150

 atagaatgat gactcaattt taattctaaa gccatgaaaa gttactttga 1200

 gactgaacaa ttctgaatta tttatgatac ccaatgtcca tgtttctttc 1250

 cctactgtaa aagaattgat cagtttcttc attaaagcag caaaaactta 1300

 ttaaatcttg taaataccat gtctctttta gatttctgtg tatgctgtga 1350

 atgaaatcat tttgagatga aattgtacaa aggcatttta aaaggctctg 1400

 catgcatcgt acctccaaac agtacatatt cggaaagtca aagattcctg 1450

 caaaataaat aaactaaaag caaacaccaa aaaaaaaaaa aaggg 1495

<210> 4506
<211> 25
<212> PRT
<213> Homo sapien

<400> 4506
 Gly Cys Leu Glu Asp Pro Asn Gln Phe Glu Gln Glu Phe Thr Gln
   1               5                  10                  15

 Leu Ser Arg Cys Leu Phe Lys Arg Ile Leu
                  20                  25

<210> 4507
<211> 2546
<212> DNA
<213> Homo sapien

<400> 4507
 gtgaggagga agctcgcgct gctcttcgcc atgctctgcg tctggctcta 50

 tatgttcctg tactcgtgcg ccggctcctg cgccgccgcg ccggggctgc 100

 tgctcctggg ctctgggtcc cgcgccgcac acgacccgcc agccctggcc 150

 acagctccgg acgggacgcc ccccaggctg ccgttccggg cgccgccagc 200

 caccccactg gcttcaggca aggagatggc cgagggcgct gcgagcccgg 250

 aggagcagag tcccgaggtg ccggactccc caagccccat ctccagcttt 300

 ttcagtgggt ctgggagcaa gcagctgccg caggccatca tcatcggcgt 350

 gaagaagggc ggcacgcggg cgctgctgga gtttctgcgc gtgcaccccg 400

 acgtgcgcgc cgtgggcgcc gagccccatt tcttcgatcg cagctacgac 450

 aagggcctcg cttggtaccg ggacctgatg cccagaaccc tggacgggca 500

 gatcaccatg gagaagacgc ccagttactt cgtcacgcgg gaggcccccg 550

 cgcgcatctc ggccatgtcc aaggacacca agctcatcgt ggtggtgcgg 600

 gacccggtga ccagggccat ctcggactac acgcagacgc tgtccaagcg 650

 gcccgacatc cccaccttcg agagcttgac gttcaaaaac aggacagcgg 700

 gcctcatcga cacgtcgtgg agcgccatcc agatcggcat ctacgccaag 750

 cacctggagc actggctgcg ccacttcccc atccgccaga tgctcttcgt 800

 gagcggcgag cggctcatca gcgacccggc cggggagctg ggccgcgtgc 850

 aagacttcct gggcctcaag aggatcatca cggacaagca cttctacttc 900

 aacaagacca agggcttccc ctgcctgaag aaggcggagg gcagcagccg 950

 gccccattgc ctgggcaaga ccaagggcag gacccatcct gagatcgacc 1000

 gcgaggtggt ccgcaggctg cgcgagttct accggccttt caacctcaag 1050

 ttctaccaga tgaccgggca cgactttggc tgggattgag cagacccggg 1100

 ctatgtacct tacccacgtg gcttatctat tgacagagat tatatcataa 1150

 catggcttga agtaaaaggc agtatccaag tccttcacct ggtcttgccc 1200

 tgtctacttt ctgatcattc tgatggtctg atgtggctgt tgatgtggaa 1250

 ctgcagaaga gttcagagaa gagtatgcaa caaagccata ggaaaacaca 1300

 caggagcttt tccctcccct tcaggtcccc gccctctttc caagctggac 1350

 aattttttat taagttgttt attccctgcc ttaaaactga aacaggaaat 1400

 tttctggtag aaggagggtc atttagtcac gaacactgaa gtgggtcaaa 1450

 attctattct gggtcaaatc cttgaattca aacagatgtc cataatcagt 1500

 actgatggaa tagagcaagt ttttctatgt aagacaaata aatcaaacat 1550

 catgtgcatc tcctcataag ggtctgcaag ggtctgatgg tttaaagttc 1600

 ctaacagatc tggttgcagc atctgccgga gcttgcaccc catcatcgga 1650

 cggtcatctt cctgctgcag aagttaggta acataagact tagatttctt 1700

 cctgttctag caatctgcaa gaccaccagg cttaactttt tagctgccag 1750

 aagacaaacc cccttttctg tttcggcaat ttgtcctggc acgtgttttg 1800

 gacttcctcc gatttacacg aaaagctctg atattcattg gagtacttta 1850

 ttttttttcc tcagttttgt ttcttttctc atgtaaaaac aaacaaaaag 1900

 gtcaacaaaa aaaaattgag gtttttcttg tttctatcta gttcatgctt 1950

 tctttgcggt gtttgaacag tagtctgtta acttagtagg tggtacctgg 2000

 aaaggtattt taagtatagt gactgtttaa taaatactta attggatgat 2050

 ggaggaggag aaattgtttt cttcccagga ttctctttgg gggtcatttt 2100

 gtgtgacaga tatattttag acatttggag aaacagtttc agatcctgcc 2150

 aggatatttt tgtaaaaaag gaaaatggaa gattccaata aactagaaac 2200

 agtacgtatc taagatgctg acacagaagc taatgtgact tttcagctta 2250

 tcaagaggat ggccaataaa acttaaaggt gtggttagat gttttctcac 2300

 ttttgtgaca ttaatttatc actgagtctc attcaaccaa gtaatctaaa 2350

 atactgtgca aattctagca gtatgtcttc gataacttgg atgttaggat 2400

 agccaatatg tacaaaaaat taaatcaagt attttgtcct atgtataaca 2450

 caaattaatt ttacacagag aaagatgttt ctaggcaagt gaaattctgg 2500

 taattcatac tatttctttg tatgaacaaa taaaatatat tttgcc 2546

<210> 4508
<211> 352
<212> PRT
<213> Homo sapien

<400> 4508
 Met Leu Cys Val Trp Leu Tyr Met Phe Leu Tyr Ser Cys Ala Gly
   1               5                  10                  15

 Ser Cys Ala Ala Ala Pro Gly Leu Leu Leu Leu Gly Ser Gly Ser
                  20                  25                  30

 Arg Ala Ala His Asp Pro Pro Ala Leu Ala Thr Ala Pro Asp Gly
                  35                  40                  45

 Thr Pro Pro Arg Leu Pro Phe Arg Ala Pro Pro Ala Thr Pro Leu
                  50                  55                  60

 Ala Ser Gly Lys Glu Met Ala Glu Gly Ala Ala Ser Pro Glu Glu
                  65                  70                  75

 Gln Ser Pro Glu Val Pro Asp Ser Pro Ser Pro Ile Ser Ser Phe
                  80                  85                  90

 Phe Ser Gly Ser Gly Ser Lys Gln Leu Pro Gln Ala Ile Ile Ile
                  95                 100                 105

 Gly Val Lys Lys Gly Gly Thr Arg Ala Leu Leu Glu Phe Leu Arg
                 110                 115                 120

 Val His Pro Asp Val Arg Ala Val Gly Ala Glu Pro His Phe Phe
                 125                 130                 135

 Asp Arg Ser Tyr Asp Lys Gly Leu Ala Trp Tyr Arg Asp Leu Met
                 140                 145                 150

 Pro Arg Thr Leu Asp Gly Gln Ile Thr Met Glu Lys Thr Pro Ser
                 155                 160                 165

 Tyr Phe Val Thr Arg Glu Ala Pro Ala Arg Ile Ser Ala Met Ser
                 170                 175                 180

 Lys Asp Thr Lys Leu Ile Val Val Val Arg Asp Pro Val Thr Arg
                 185                 190                 195

 Ala Ile Ser Asp Tyr Thr Gln Thr Leu Ser Lys Arg Pro Asp Ile
                 200                 205                 210

 Pro Thr Phe Glu Ser Leu Thr Phe Lys Asn Arg Thr Ala Gly Leu
                 215                 220                 225

 Ile Asp Thr Ser Trp Ser Ala Ile Gln Ile Gly Ile Tyr Ala Lys
                 230                 235                 240

 His Leu Glu His Trp Leu Arg His Phe Pro Ile Arg Gln Met Leu
                 245                 250                 255

 Phe Val Ser Gly Glu Arg Leu Ile Ser Asp Pro Ala Gly Glu Leu
                 260                 265                 270

 Gly Arg Val Gln Asp Phe Leu Gly Leu Lys Arg Ile Ile Thr Asp
                 275                 280                 285

 Lys His Phe Tyr Phe Asn Lys Thr Lys Gly Phe Pro Cys Leu Lys
                 290                 295                 300

 Lys Ala Glu Gly Ser Ser Arg Pro His Cys Leu Gly Lys Thr Lys
                 305                 310                 315

 Gly Arg Thr His Pro Glu Ile Asp Arg Glu Val Val Arg Arg Leu
                 320                 325                 330

 Arg Glu Phe Tyr Arg Pro Phe Asn Leu Lys Phe Tyr Gln Met Thr
                 335                 340                 345

 Gly His Asp Phe Gly Trp Asp
                 350

<210> 4509
<211> 1174
<212> DNA
<213> Homo sapien

<400> 4509
 agcggtgtcc gtgtccctga gttaagaatg gtttttaggc ttgtatagga 50

 ttaaaaaaaa aaaaaaaacc cacagaaaaa tgtaggcagc ccagcataag 100

 ataccgcctt tcacagaaat gtttgctgac cccggaactg tcactctcgg 150

 gttacaagag tttgtttctt tgaaacagtc tggctctgtc acccaggctg 200

 gagtgcagtg gcatgatctc gggtcactgc agcctccacc tcccgggttc 250

 aagcaattct gcctcagcct cctgagtagc tgggattaca ggtgtgcacc 300

 accacagaca gctaatttta caggtgtaca ccaccacacc caagaatcgt 350

 ttgaacccgg gaggtggggg ttgcagtgag ccgcgatcat agcactgtac 400

 tccagtctgg gtgacacact gtctgaaaaa taaaagttta gttctaggta 450

 caaattaagt ggtctaccca acaggaagct gtgaaattag aagtaatttt 500

 aaagcatact ttacacctct atataatcaa agtaagggca agataaaact 550

 tgttagtaaa acatgtttta ttatttttta gataggtagc ctgcaacata 600

 aaatatattt tgaaagctgt taaggggtgt ataatctgtt aaaaaatacc 650

 atgattagta tttcacattt agtgactcag atccctttgt gtaagtcctt 700

 tgcgttgtgc aaagaggttt ttctatgaga tgagaattat gaacacttca 750

 tataggtaaa ttccataggt tgagctgggg cagaaattaa tggctcctgg 800

 agattgcatc tttttttttt ttttttttga gcttagaatt cccatttgga 850

 cagaatttag cttttgtgct gttgattact tctgtactaa actggtagcc 900

 aattgttcac ttctaaatgg aagggaaaaa gttacccaca caagttagaa 950

 aatgatttac cgaattattt ttttgagtta gtatgtatat actgttttaa 1000

 atcagtaatg tttgttcctt ttgctgccca tttgggagta tgtggcaatt 1050

 cctagtgctc ttgtatgaca ttactcttct tgagacttgt atatgcaaga 1100

 aagtatatat aaaagatgcc tggtggtaaa aaaaaaaaaa aaaaaaaaaa 1150

 aaaaaaagaa aaaaaaaaaa aaaa 1174

<210> 4510
<211> 86
<212> PRT
<213> Homo sapien

<400> 4510
 Met Phe Ala Asp Pro Gly Thr Val Thr Leu Gly Leu Gln Glu Phe
   1               5                  10                  15

 Val Ser Leu Lys Gln Ser Gly Ser Val Thr Gln Ala Gly Val Gln
                  20                  25                  30

 Trp His Asp Leu Gly Ser Leu Gln Pro Pro Pro Pro Gly Phe Lys
                  35                  40                  45

 Gln Phe Cys Leu Ser Leu Leu Ser Ser Trp Asp Tyr Arg Cys Ala
                  50                  55                  60

 Pro Pro Gln Thr Ala Asn Phe Thr Gly Val His His His Thr Gln
                  65                  70                  75

 Glu Ser Phe Glu Pro Gly Arg Trp Gly Leu Gln
                  80                  85

<210> 4511
<211> 3233
<212> DNA
<213> Homo sapien

<400> 4511
 agagtttgcg ccggttcgca ttccccggcc tcccgttcgc tcccccgcga 50

 accaggcggc cgtgcgcctc tcggggcaac cacccaagag cacccgggcg 100

 ggaggacgcc gagcaggggg tgttgcgggc tgggacaggg gcagccacct 150

 cccgaagatg caggatggca gcagagccgc agccgtccag cctttcctac 200

 cgcaccacgg gctccaccta cctgcacccg ctcagcgagc tcctgggcat 250

 cccgctggac caggtgaatt ttgtggtatg ccagcttgtt gctctgtttg 300

 ctgctttctg gtttcgcatc tacttacgtc ctggtacaac cagctctgat 350

 gtccggcatg cggttgccac catttttggc atctattttg tcatcttttg 400

 tttcggctgg tactctgtgc atctttttgt gctggtgtta atgtgctatg 450

 caatcatggt cactgctagt gtatccaata ttcacagata ttcctttttt 500

 gtagcaatgg gatatcttac aatatgccac atcagccgaa tatacatctt 550

 ccactatgga attctcacta cggatttttc tgggcctctg atgattgtca 600

 ctcagaagat cacaaccttg gcattccagg ttcatgatgg attaggtcga 650

 agagctgaag acctttctgc tgaacaacat cgacttgcta tcaaagtgaa 700

 accctctttt ttggaatact taagttacct tctcaatttc atgagtgtca 750

 tagctggtcc ttgtaacaat ttcaaggact acatagcctt cattgagggg 800

 aagcatatac acatgaagtt gctggaggtg aactggaagc gaaaaggttt 850

 ccacagcttg ccagaacctt ctcccacagg agctgtgata cacaagttgg 900

 gcatcacctt ggtgtctctc cttttgtttt tgacgctaac gaagaccttt 950

 cctgtcacct gccttgtgga tgactggttt gtccataaag caagctttcc 1000

 ggctcgactc tgctacttat atgttgtcat gcaagcctca aagcccaagt 1050

 attactttgc atggacatta gctgatgcag tgaataacgc agctggcttt 1100

 gggttcagcg gagtggataa gaatgggaat ttctgttggg atctgctttc 1150

 gaacctaaac atctggaaaa ttgagactgc cacaagtttc aaaatgtact 1200

 tggaaaactg gaatattcag acagctactt ggctaaagtg tgtgtgctat 1250

 cagcgggttc atggtacccc acggtgctaa ccttcatcct gtctgctttg 1300

 tggcatggtg tctaccctgg atactatttt accttcttaa ctggaattct 1350

 tgtcacatta gcagctagag cggtcaggaa caactacaga cattacttcc 1400

 tttcttcaag agctctcaag gctgtgtatg atgcaggcac ctgggccgtc 1450

 actcagctgg ctgtctctta cacggtagca ccctttgtga tgttggcagt 1500

 tgaaccgacc atcagcttat acaagtccat gtacttttat ttgcacatca 1550

 taagtctcct gataatacta tttctgccaa tgaaaccaca agctcatacg 1600

 caaaggcggc ctcagactct gaactctatt aataagagaa aaacagattg 1650

 atacctccaa gagaagcgga acaagcaaaa ctgcagaacg ttcgaaagat 1700

 gagatgacaa ggcttcaagg gctcctccgg tggcttagag gcgatgttta 1750

 catgcatctt tattttgttc ttttttaaag tgcagggagt attttttttt 1800

 tttttttttt tttttttttg agacggagtc tcgctctgtc gcccaggctg 1850

 gagtgcagtg gcgggatctc ggctcactgc aagctccgcc tcccgggttc 1900

 acgccattct cctgcctcag cctcccaagt agctgggact acaggcgccc 1950

 gccactacgc ccggctaatt ttttgtattt ttagtagaga cggggtttca 2000

 ccgttttagc cgggatggtc tcgatctcct gacctcgtga tccgcccgcc 2050

 tcggcctccc aaagtgctgg gattacaggc gtgagccacc gcgcccggcc 2100

 gggagtattt ttataaagcc tttttgtaca gattaatcgg ccatgtccag 2150

 gttattggtt ttgatatttt ataggacatt tgagtggtgt ggcgatgtgt 2200

 agagaatgtg ccagagctgc agagacagtc cattctgggc tgctggcttt 2250

 ttgcccttcc tgcatgattt ccagctactg tgacctggat gctgggaacc 2300

 caggcatcgg ctccaaaaat tagaaggcga gtgctgagaa gacttgtcac 2350

 aggtttctca aatcagaata tactcagtca tagtggttcc ctgggaagcc 2400

 ccagaccctt tgacttgtga cattactggt ttgcagacat aataactaca 2450

 ctcagaggac catggaggca gagggatcat ggtttcaggg cactgaaaac 2500

 tctacgagcc aagaggacta gtgcatggac tgaaagtcag gcatgccctc 2550

 aaataggctg tattttcttt ccaggaatgt aacctttccc ctttttcttc 2600

 tgacctgagc caagattgga aatcagaaag tctcctgtac atggagctga 2650

 agaggggctg ctgttttccg aatgttttcc atttcacagg cgccacctgc 2700

 ttgcccgggg ttggtcttga gaagacaccc aaatgttcat gcctcagaaa 2750

 ggcagcagaa tgccttttag gaaatttttt taaagtaatt tgaagttata 2800

 tagaagtttg gtaagaagaa gcagttgttt ctctcttttc tccctcattt 2850

 catggaggtg ttaatgatca tggctggccg tgatgtacac atgggctgat 2900

 tttcattttt tcagtttcat agctgagaaa ttcagctttg ttttagttga 2950

 atcatcatat tggaaagcag acattgaaag ttttcttttc tatctttgtt 3000

 atgaatgtgc tatggcccct tttggagact tctattgggt aatattctat 3050

 gtgagagaag gaaacttggt attaaatgtt gtggaaaata ataatgatga 3100

 taataataaa gtatatgctg caatggtgta ctgccaatca gattgcttgg 3150

 gagaagaaaa tttattcaaa tccaacgata aaaaattaat ttcttattga 3200

 ataaacagta tgttcccaaa aaaaaaaaaa aaa 3233

<210> 4512
<211> 371
<212> PRT
<213> Homo sapien

<400> 4512
 Met Ala Ala Glu Pro Gln Pro Ser Ser Leu Ser Tyr Arg Thr Thr
   1               5                  10                  15

 Gly Ser Thr Tyr Leu His Pro Leu Ser Glu Leu Leu Gly Ile Pro
                  20                  25                  30

 Leu Asp Gln Val Asn Phe Val Val Cys Gln Leu Val Ala Leu Phe
                  35                  40                  45

 Ala Ala Phe Trp Phe Arg Ile Tyr Leu Arg Pro Gly Thr Thr Ser
                  50                  55                  60

 Ser Asp Val Arg His Ala Val Ala Thr Ile Phe Gly Ile Tyr Phe
                  65                  70                  75

 Val Ile Phe Cys Phe Gly Trp Tyr Ser Val His Leu Phe Val Leu
                  80                  85                  90

 Val Leu Met Cys Tyr Ala Ile Met Val Thr Ala Ser Val Ser Asn
                  95                 100                 105

 Ile His Arg Tyr Ser Phe Phe Val Ala Met Gly Tyr Leu Thr Ile
                 110                 115                 120

 Cys His Ile Ser Arg Ile Tyr Ile Phe His Tyr Gly Ile Leu Thr
                 125                 130                 135

 Thr Asp Phe Ser Gly Pro Leu Met Ile Val Thr Gln Lys Ile Thr
                 140                 145                 150

 Thr Leu Ala Phe Gln Val His Asp Gly Leu Gly Arg Arg Ala Glu
                 155                 160                 165

 Asp Leu Ser Ala Glu Gln His Arg Leu Ala Ile Lys Val Lys Pro
                 170                 175                 180

 Ser Phe Leu Glu Tyr Leu Ser Tyr Leu Leu Asn Phe Met Ser Val
                 185                 190                 195

 Ile Ala Gly Pro Cys Asn Asn Phe Lys Asp Tyr Ile Ala Phe Ile
                 200                 205                 210

 Glu Gly Lys His Ile His Met Lys Leu Leu Glu Val Asn Trp Lys
                 215                 220                 225

 Arg Lys Gly Phe His Ser Leu Pro Glu Pro Ser Pro Thr Gly Ala
                 230                 235                 240

 Val Ile His Lys Leu Gly Ile Thr Leu Val Ser Leu Leu Leu Phe
                 245                 250                 255

 Leu Thr Leu Thr Lys Thr Phe Pro Val Thr Cys Leu Val Asp Asp
                 260                 265                 270

 Trp Phe Val His Lys Ala Ser Phe Pro Ala Arg Leu Cys Tyr Leu
                 275                 280                 285

 Tyr Val Val Met Gln Ala Ser Lys Pro Lys Tyr Tyr Phe Ala Trp
                 290                 295                 300

 Thr Leu Ala Asp Ala Val Asn Asn Ala Ala Gly Phe Gly Phe Ser
                 305                 310                 315

 Gly Val Asp Lys Asn Gly Asn Phe Cys Trp Asp Leu Leu Ser Asn
                 320                 325                 330

 Leu Asn Ile Trp Lys Ile Glu Thr Ala Thr Ser Phe Lys Met Tyr
                 335                 340                 345

 Leu Glu Asn Trp Asn Ile Gln Thr Ala Thr Trp Leu Lys Cys Val
                 350                 355                 360

 Cys Tyr Gln Arg Val His Gly Thr Pro Arg Cys
                 365                 370

<210> 4513
<211> 2318
<212> DNA
<213> Homo sapien

<400> 4513
 ttcaccattg ctgtttttct ggtgagacat gtggaaagga aggacaggtg 50

 gacttttcaa ctaactagct ctctgatttt taataagata cctcagttct 100

 ttggcctcag tttacttatc tgtacaaaga gtaagtcata tgcttaatca 150

 ctaagatctg ttagatactg cagttaagat tctttatcag caaattactg 200

 aactctagtg ttaacatagc tagaggtgga aaagggagca agaccaggtg 250

 ttgggatgaa taattaacta atcgagataa catcagtttt caccatagga 300

 acaagtacca tggttgctct taaagtaaga gatgtttcct attttatgta 350

 attttactaa gggataatgt tttcttttgt cactgattta aatgtacctg 400

 gatgtttctc agccatttgg ctaagatcga acacaagtaa tacctgggcc 450

 ttttatatct aatctaatgt agaccagcct gttaaaagag aaagacaatt 500

 ggttaaactg ctgatgtgtt gctttgtctt ctcaaaagct tgttctataa 550

 tacaatatgt aaaaagttgt tacagtgtag taactgtaga taatcccttt 600

 atgatttgta cctaatggcg aagacctttt attttctgaa aataacgtgt 650

 ttgttttcat taccaacatt agaagccaat atttattaat ctatttctca 700

 tcctgacatt tcagtcagac tcttaaaata atcttgctgt gttttgattt 750

 aatgtgctta tcaacttata atattgaatt aatgttaata gtgtcatttt 800

 aggtgaacta gacttcattg aaggaggtgg gagccttatg gagagagagt 850

 atatgattat ctctatttgt atttaattac catttcatct aaccattcag 900

 aacatatttc aagaataatt ttaattcaag ttgtaggtaa aacttactat 950

 accattttca ttttgacgct ttccaagaat gagatacacg gtattttaaa 1000

 gacaaagatt gatcttacat gttactatta aaaaaaacac gataattttg 1050

 ttctacattt atacttttaa tttttctgtg gataataaga aatgccaaga 1100

 gtcgattgtg tccatgctgg caagtggcct aataaattgt ccttttattt 1150

 ggtggtcctc agagtggcag ttaacatctt gctattctgc cttgtggact 1200

 tgaggtggaa aggttcatgg aattatatcc ttgcttttgg atgtgcaaac 1250

 tgaaggctca gagagtttaa gacacatagt cactttcacc aattaaatga 1300

 tgaagctgcc atgtaaacgt atttcatcac actcccgaga ccttcttctc 1350

 cagtagtgtt ttcaagcttt ttgagcatgc agacactacc atcaaaaaat 1400

 tatgtagaga catacttgag agttacagtt taaagaaaaa caaggtgtaa 1450

 ttatttggtt attagtagca tttacatatg cttgaaaact tctgctatat 1500

 atacagtaag attaatttat tctaacaatg atcttgataa tccccctgat 1550

 tcccagactc cttggaatag ctccacagct atcagtggtt ctgccacagg 1600

 ttcagagcct tcccagtact gccttcttat ttgagaggtg tgctaagagc 1650

 tataaagcag aggcttcaat tgtacacagt ttggaagttt aggcaaaagt 1700

 catttcttcc ctatattttg tcatgcttat ctcctgtctc tttctgtttt 1750

 acagattagc aataaactcc ttaaaaccca aaggtttggg cttctgttcc 1800

 tttcacttgc agtcagacat ggagttagtg gtagaaggaa cagaaggggt 1850

 aacctgcatg gtgacagcta ctgaggggat ggataggaaa gcaggctgag 1900

 tccctggggc cagtggttac caaagccaag gagagagcaa ggggagccca 1950

 gtgggcctgg ccatggactg ctctggaatt ccgagtgtga actttcagcc 2000

 aggaatgtat tgtgaaaata ttactgtgag gttttaaaag tacacaaata 2050

 acaattgttt tttgtaaaaa ggaaaaaaaa aagttagaaa aagagatatg 2100

 ccaaaaagaa gaaagtaaaa aatacatgac ttctgtcttc tgttaacata 2150

 ttaaaattta ttcttttaga tttttatgtg tctatataca tgtaaaatat 2200

 atatgcatcc cccaaattgt attatactct tttgagacct cacatttttt 2250

 tcacccaaga atataacatt aatttctttc ctttagaaaa gacatgagac 2300

 taaagaatgt ttattgag 2318

<210> 4514
<211> 48
<212> PRT
<213> Homo sapien

<400> 4514
 Phe Thr Ile Ala Val Phe Leu Val Arg His Val Glu Arg Lys Asp
   1               5                  10                  15

 Arg Trp Thr Phe Gln Leu Thr Ser Ser Leu Ile Phe Asn Lys Ile
                  20                  25                  30

 Pro Gln Phe Phe Gly Leu Ser Leu Leu Ile Cys Thr Lys Ser Lys
                  35                  40                  45

 Ser Tyr Ala


<210> 4515
<211> 2253
<212> DNA
<213> Homo sapien

<400> 4515
 ctcaaaaaca gtcattccta tgaattgagg tgtacaaagt ttgaatttgt 50

 atcaaagatg taattattat ttttaaaacc ttttcactat actgctgctg 100

 taattacttt gatttttaaa atgtagatta attttttttt tttggcttca 150

 ggtgtgtatc caccaagaat ttcaaattta tgtggattta ttttattggt 200

 acataatctg taaacttctt aaggcattaa catgaaaagt ttttttcttt 250

 ttattttata ttgtggctca ggttatattt tgaagatgtt ttgagtttat 300

 cctccaatag gcaatgaagt tgacaaggtt ttatgaagga ataaccaagt 350

 ccctggagtc ctgtggctgt tgccacagta atgcgtcctg ctgtaaacag 400

 gacaggtgtg tcctgttgag aatgtgagcg ggctcttcca gcctcctggt 450

 ccctcctgac tctgccacgc ccctcacctc actggcactt cgataactga 500

 ctggacgtgt taatgggtct tttagggttc taaagggtga accacacttt 550

 taaagccccg gctgtggttc ggagggttag tgctgtatgc cttttatttc 600

 cctttccctt tgaggtactg aaaggatgaa aaggtggtgt catgttttgg 650

 ggagaatctt acttctcaaa tggaaattgc actttttgct gaatcctttg 700

 catttttttg gtagtaagca gttcattgag tatcaggtcc tcaaaggaat 750

 gagttggccc ggctagggtg ggccctcttg acctaacttc agagggggcc 800

 ttggctcagt aggtgtgaat cagggaagcc acattgtcct cagggtgctg 850

 tatgaagctg ggtgtgggcg gattcctccc acaccttcac actggcctgc 900

 ctccaactca tacagatctc ggagcggtcg gtacttcatt cataggtccc 950

 tgttcaggca gcagttctgt gggctgtggc cctctcccct ccaatatgtc 1000

 cgaaaccatt gtgatgggtg gcaaatccca gggagctcct aagccctgct 1050

 ctgcccacat cactgccaca gagaagtcag aggaagggac ttgttgctaa 1100

 aaaatccttt aaaaggttaa atactttaaa agattaaagc aacataactg 1150

 taaacatatc gtataaaaat gaaaaacaca ggaaccctct tcccttccgc 1200

 ctggtgtggg cttgggaaat gggcaagcgg ccccagcaat catgggagga 1250

 actcttgcgg gggagcggtc tgggattcca aatgggcagg tcacacgaag 1300

 gtcacgatgc ttctctgcat cctgaaaagg gctggggaca gggccagtgg 1350

 gggtggtaag ggtatttata gcacagtgct tgaaaaggga agattaatgt 1400

 gtaaatataa aggacacaca ggctgggggt tggtcagagg caagaggagg 1450

 gtgcctctga gcttcaaccc ctcccaggaa caatgagctc aaattggaag 1500

 agtccagtgg aatcgggggg atggtgtgag cgcccctgtt cagtctttga 1550

 caattgcata cagaaaagca gctggtatgg gtttgggtgt caatgaaagg 1600

 gccaaagact ggtggccagc tggtttgggg gatttgggcc attgatagca 1650

 tctcccagga acaacgactt tttgcctcca aagttggatc tagtgatgat 1700

 cagcaccagc aggaaatgac atttggtgtc tgcccactgc agccatactg 1750

 tgacctccag ccagacttcc gcctaattga ctccactgga tttgtgctct 1800

 gttgagtcag aggctcccgg gggttgggga tcgaggggcg ggggtcagct 1850

 atgcagccca tcacgtgtgt ttttcatctg ggatgaaaaa gcctggttct 1900

 cttttgaaat gcttgattgt acttattgag ctaaacaagt cttggtgact 1950

 gttgttgatt tgcctcaaaa gttttaagtc ctgggttttc agactactgt 2000

 gtagcagctg tgtgtttaac atactgtagc tttttctccc ttgggggcac 2050

 atacaaatag gatgtgttga tgtggactct aaactgtaat tttcctgtaa 2100

 ctattttgga atgatgcata tttctaatgt ttgttatact tgtacagagt 2150

 attgctgttg gttgcttttt ttttttttaa ggaaaaaatg gcctgaaaac 2200

 atttttttaa agacttacaa ataccaaata taaaaaaatg tcaatgcaaa 2250

 aaa 2253

<210> 4516
<211> 105
<212> PRT
<213> Homo sapien

<400> 4516
 Met Lys Asn Thr Gly Thr Leu Phe Pro Ser Ala Trp Cys Gly Leu
   1               5                  10                  15

 Gly Lys Trp Ala Ser Gly Pro Ser Asn His Gly Arg Asn Ser Cys
                  20                  25                  30

 Gly Gly Ala Val Trp Asp Ser Lys Trp Ala Gly His Thr Lys Val
                  35                  40                  45

 Thr Met Leu Leu Cys Ile Leu Lys Arg Ala Gly Asp Arg Ala Ser
                  50                  55                  60

 Gly Gly Gly Lys Gly Ile Tyr Ser Thr Val Leu Glu Lys Gly Arg
                  65                  70                  75

 Leu Met Cys Lys Tyr Lys Gly His Thr Gly Trp Gly Leu Val Arg
                  80                  85                  90

 Gly Lys Arg Arg Val Pro Leu Ser Phe Asn Pro Ser Gln Glu Gln
                  95                 100                 105

<210> 4517
<211> 3132
<212> DNA
<213> Homo sapien

<400> 4517
 ccgcagaact tggggagccg ccgccgccat ccgccgccgc agccagcttc 50

 cgccgccgca ggaccggccc ctgccccagc ctccgcagcc gcggcgcgtc 100

 cacgcccgcc cgcgcccagg gcgagtcggg gtcgccgcct gcacgcttct 150

 cagtgttccc cgcgccccgc atgtaacccg gccaggcccc cgcaacggtg 200

 tcccctgcag ctccagcccc gggctgcacc cccccgcccc gacaccagct 250

 ctccagcctg ctcgtccagg atggccgcgg ccaaggccga gatgcagctg 300

 atgtccccgc tgcagatctc tgacccgttc ggatcctttc ctcactcgcc 350

 caccatggac aactacccta agctggagga gatgatgctg ctgagcaacg 400

 gggctcccca gttcctcggc gccgccgggg ccccagaggg cagcggcagc 450

 aacagcagca gcagcagcag cgggggcggt ggaggcggcg ggggcggcag 500

 caacagcagc agcagcagca gcaccttcaa ccctcaggcg gacacgggcg 550

 agcagcccta cgagcacctg accgcagagt cttttcctga catctctctg 600

 aacaacgaga aggtgctggt ggagaccagt taccccagcc aaaccactcg 650

 actgcccccc atcacctata ctggccgctt ttccctggag cctgcaccca 700

 acagtggcaa caccttgtgg cccgagcccc tcttcagctt ggtcagtggc 750

 ctagtgagca tgaccaaccc accggcctcc tcgtcctcag caccatctcc 800

 agcggcctcc tccgcctccg cctcccagag cccacccctg agctgcgcag 850

 tgccatccaa cgacagcagt cccatttact cagcggcacc caccttcccc 900

 acgccgaaca ctgacatttt ccctgagcca caaagccagg ccttcccggg 950

 ctcggcaggg acagcgctcc agtacccgcc tcctgcctac cctgccgcca 1000

 agggtggctt ccaggttccc atgatccccg actacctgtt tccacagcag 1050

 cagggggatc tgggcctggg caccccagac cagaagccct tccagggcct 1100

 ggagagccgc acccagcagc cttcgctaac ccctctgtct actattaagg 1150

 cctttgccac tcagtcgggc tcccaggacc tgaaggccct caataccagc 1200

 taccagtccc agctcatcaa acccagccgc atgcgcaagt atcccaaccg 1250

 gcccagcaag acgccccccc acgaacgccc ttacgcttgc ccagtggagt 1300

 cctgtgatcg ccgcttctcc cgctccgacg agctcacccg ccacatccgc 1350

 atccacacag gccagaagcc cttccagtgc cgcatctgca tgcgcaactt 1400

 cagccgcagc gaccacctca ccacccacat ccgcacccac acaggcgaaa 1450

 agcccttcgc ctgcgacatc tgtggaagaa agtttgccag gagcgatgaa 1500

 cgcaagaggc ataccaagat ccacttgcgg cagaaggaca agaaagcaga 1550

 caaaagtgtt gtggcctctt cggccacctc ctctctctct tcctacccgt 1600

 ccccggttgc tacctcttac ccgtccccgg ttactacctc ttatccatcc 1650

 ccggccacca cctcataccc atcccctgtg cccacctcct tctcctctcc 1700

 cggctcctcg acctacccat cccctgtgca cagtggcttc ccctccccgt 1750

 cggtggccac cacgtactcc tctgttcccc ctgctttccc ggcccaggtc 1800

 agcagcttcc cttcctcagc tgtcaccaac tccttcagcg cctccacagg 1850

 gctttcggac atgacagcaa ccttttctcc caggacaatt gaaatttgct 1900

 aaagggaaag gggaaagaaa gggaaaaggg agaaaaagaa acacaagaga 1950

 cttaaaggac aggaggagga gatggccata ggagaggagg gttcctctta 2000

 ggtcagatgg aggttctcag agccaagtcc tccctctcta ctggagtgga 2050

 aggtctattg gccaacaatc ctttctgccc acttcccctt ccccaattac 2100

 tattcccttt gacttcagct gcctgaaaca gccatgtcca agttcttcac 2150

 ctctatccaa agaacttgat ttgcatggat tttggataaa tcatttcagt 2200

 atcatctcca tcatatgcct gaccccttgc tcccttcaat gctagaaaat 2250

 cgagttggca aaatggggtt tgggcccctc agagccctgc cctgcaccct 2300

 tgtacagtgt ctgtgccatg gatttcgttt ttcttggggt actcttgatg 2350

 tgaagataat ttgcatattc tattgtatta tttggagtta ggtcctcact 2400

 tgggggaaaa aaaaaaaaaa aagccaagca aaccaatggt gatcctctat 2450

 tttgtgatga tgctgtgaca ataagtttga accttttttt ttgaaacagc 2500

 agtcccagta ttctcagagc atgtgtcaga gtgttgttcc gttaaccttt 2550

 ttgtaaatac tgcttgaccg tactctcaca tgtggcaaaa tatggtttgg 2600

 tttttctttt ttttttttga aagtgttttt tcttcgtcct tttggtttaa 2650

 aaagtttcac gtcttggtgc cttttgtgtg atgccccttg ctgatggctt 2700

 gacatgtgca attgtgaggg acatgctcac ctctagcctt aaggggggca 2750

 gggagtgatg atttggggga ggctttggga gcaaaataag gaagagggct 2800

 gagctgagct tcggttctcc agaatgtaag aaaacaaaat ctaaaacaaa 2850

 atctgaactc tcaaaagtct atttttttaa ctgaaaatgt aaatttataa 2900

 atatattcag gagttggaat gttgtagtta cctactgagt aggcggcgat 2950

 ttttgtatgt tatgaacatg cagttcatta ttttgtggtt ctattttact 3000

 ttgtacttgt gtttgcttaa acaaagtgac tgtttggctt ataaacacat 3050

 tgaatgcgct ttattgccca tgggatatgt ggtgtatatc cttccaaaaa 3100

 attaaaacga aaataaagta gctgcgattg gg 3132

<210> 4518
<211> 543
<212> PRT
<213> Homo sapien

<400> 4518
 Met Ala Ala Ala Lys Ala Glu Met Gln Leu Met Ser Pro Leu Gln
   1               5                  10                  15

 Ile Ser Asp Pro Phe Gly Ser Phe Pro His Ser Pro Thr Met Asp
                  20                  25                  30

 Asn Tyr Pro Lys Leu Glu Glu Met Met Leu Leu Ser Asn Gly Ala
                  35                  40                  45

 Pro Gln Phe Leu Gly Ala Ala Gly Ala Pro Glu Gly Ser Gly Ser
                  50                  55                  60

 Asn Ser Ser Ser Ser Ser Ser Gly Gly Gly Gly Gly Gly Gly Gly
                  65                  70                  75

 Gly Ser Asn Ser Ser Ser Ser Ser Ser Thr Phe Asn Pro Gln Ala
                  80                  85                  90

 Asp Thr Gly Glu Gln Pro Tyr Glu His Leu Thr Ala Glu Ser Phe
                  95                 100                 105

 Pro Asp Ile Ser Leu Asn Asn Glu Lys Val Leu Val Glu Thr Ser
                 110                 115                 120

 Tyr Pro Ser Gln Thr Thr Arg Leu Pro Pro Ile Thr Tyr Thr Gly
                 125                 130                 135

 Arg Phe Ser Leu Glu Pro Ala Pro Asn Ser Gly Asn Thr Leu Trp
                 140                 145                 150

 Pro Glu Pro Leu Phe Ser Leu Val Ser Gly Leu Val Ser Met Thr
                 155                 160                 165

 Asn Pro Pro Ala Ser Ser Ser Ser Ala Pro Ser Pro Ala Ala Ser
                 170                 175                 180

 Ser Ala Ser Ala Ser Gln Ser Pro Pro Leu Ser Cys Ala Val Pro
                 185                 190                 195

 Ser Asn Asp Ser Ser Pro Ile Tyr Ser Ala Ala Pro Thr Phe Pro
                 200                 205                 210

 Thr Pro Asn Thr Asp Ile Phe Pro Glu Pro Gln Ser Gln Ala Phe
                 215                 220                 225

 Pro Gly Ser Ala Gly Thr Ala Leu Gln Tyr Pro Pro Pro Ala Tyr
                 230                 235                 240

 Pro Ala Ala Lys Gly Gly Phe Gln Val Pro Met Ile Pro Asp Tyr
                 245                 250                 255

 Leu Phe Pro Gln Gln Gln Gly Asp Leu Gly Leu Gly Thr Pro Asp
                 260                 265                 270

 Gln Lys Pro Phe Gln Gly Leu Glu Ser Arg Thr Gln Gln Pro Ser
                 275                 280                 285

 Leu Thr Pro Leu Ser Thr Ile Lys Ala Phe Ala Thr Gln Ser Gly
                 290                 295                 300

 Ser Gln Asp Leu Lys Ala Leu Asn Thr Ser Tyr Gln Ser Gln Leu
                 305                 310                 315

 Ile Lys Pro Ser Arg Met Arg Lys Tyr Pro Asn Arg Pro Ser Lys
                 320                 325                 330

 Thr Pro Pro His Glu Arg Pro Tyr Ala Cys Pro Val Glu Ser Cys
                 335                 340                 345

 Asp Arg Arg Phe Ser Arg Ser Asp Glu Leu Thr Arg His Ile Arg
                 350                 355                 360

 Ile His Thr Gly Gln Lys Pro Phe Gln Cys Arg Ile Cys Met Arg
                 365                 370                 375

 Asn Phe Ser Arg Ser Asp His Leu Thr Thr His Ile Arg Thr His
                 380                 385                 390

 Thr Gly Glu Lys Pro Phe Ala Cys Asp Ile Cys Gly Arg Lys Phe
                 395                 400                 405

 Ala Arg Ser Asp Glu Arg Lys Arg His Thr Lys Ile His Leu Arg
                 410                 415                 420

 Gln Lys Asp Lys Lys Ala Asp Lys Ser Val Val Ala Ser Ser Ala
                 425                 430                 435

 Thr Ser Ser Leu Ser Ser Tyr Pro Ser Pro Val Ala Thr Ser Tyr
                 440                 445                 450

 Pro Ser Pro Val Thr Thr Ser Tyr Pro Ser Pro Ala Thr Thr Ser
                 455                 460                 465

 Tyr Pro Ser Pro Val Pro Thr Ser Phe Ser Ser Pro Gly Ser Ser
                 470                 475                 480

 Thr Tyr Pro Ser Pro Val His Ser Gly Phe Pro Ser Pro Ser Val
                 485                 490                 495

 Ala Thr Thr Tyr Ser Ser Val Pro Pro Ala Phe Pro Ala Gln Val
                 500                 505                 510

 Ser Ser Phe Pro Ser Ser Ala Val Thr Asn Ser Phe Ser Ala Ser
                 515                 520                 525

 Thr Gly Leu Ser Asp Met Thr Ala Thr Phe Ser Pro Arg Thr Ile
                 530                 535                 540

 Glu Ile Cys


<210> 4519
<211> 1038
<212> DNA
<213> Homo sapien

<400> 4519
 acctacactt ggagcccagg tccagcgttc ccccgaccgc tttcccctac 50

 ctcccggccc ccgctcccgc cccagcactt ttggctctgt tgcgtgggga 100

 tgcggggaga tttgagaggg gaaaaccccg ccaggaggga gagagaggca 150

 cccctctggg atgcgggtga gggaaggttg gctgaagttc ctagtctcag 200

 gccgtaggtg cctggccagt ttcctgtttg tggggcagct ggggcctgag 250

 gaggaggggt tcacttcctc ctcccacccc ctgggagcgg ccctgcgctg 300

 tcactgacat ctcattaaaa aaaaaaaaaa atttgctctc aaggtgtttg 350

 aggctttaat gcaacccttt agcccttggt tctttttggt gcaagaattc 400

 tggctgttta cctcagactc agacccctga aatgttgcca aattcttcaa 450

 ataactgttt ggggggtggg gggagatgaa agagagtcgc gttttgttta 500

 cagttaaaga catccaatat cttaaaaagg agttttcctt tagaaacaca 550

 cacacccttc ctcttgctca aaagatctca ctccatgata ctgtgtaaaa 600

 tatttttgca ctgttgtgaa gtatttttga cttttttctg tacataactg 650

 tgttctcaga gctgaatgtt tatatctttt gctgtgcaaa agaaacatgt 700

 aaaatgttgt tcagttgtat atacagaaat gtgtataaaa cattttgtta 750

 ttttttaaaa gtagcactgt tctggttctg tttgcacgcc agtggggaga 800

 gaataaagag gaaaatttaa cagaacaggt gagcgtctgg aactgctgcg 850

 ttggggtggg agaggctgtg tctgaccctg ggatggtgtc ataagacagt 900

 ctttggcctt tcctgtgctt ggagagaatt agggaaggaa ggtccacttt 950

 atgcgccatc tggggccttc ctggacctcc acaactctgg gtgctgtgtc 1000

 tgggaccagc cttttcttgt attatcctgt atttttca 1038

<210> 4520
<211> 29
<212> PRT
<213> Homo sapien

<400> 4520
 Met Arg His Leu Gly Pro Ser Trp Thr Ser Thr Thr Leu Gly Ala
   1               5                  10                  15

 Val Ser Gly Thr Ser Leu Phe Leu Tyr Tyr Pro Val Phe Phe
                  20                  25

<210> 4521
<211> 2178
<212> DNA
<213> Homo sapien

<400> 4521
 acttccggtc gctttcggtc tctcagcggc cggtttctgc gtccgctgcc 50

 gcaggttcca ccgcgctcca ggtatttttt tttctgaagg aaagctgctt 100

 cctcatatgt ttcaagaatg gctctcccta tcattgtaaa atggggtgga 150

 caggagtatt cagtgaccac actttcagaa gatgatactg tgctcgatct 200

 caaacagttt ctcaagaccc ttacaggagt tcttccagaa cgccaaaagt 250

 tacttggact caaagttaaa ggcaaacctg cagaaaatga tgttaagctt 300

 ggagctctca aactgaaacc aaatactaaa atcatgatga tgggaactcg 350

 tgaggagagc ttgggagatg tcttaggtcc accccctgac aatgatgatg 400

 ttgttaatga ctttgatatt gaagatgaag tagttgaagt agaaaatagg 450

 gaagaaaacc tactgaaaat ttctcgcaga gtgaaagagt acaaagtgga 500

 aattttgaat cctcccaggg aagggaaaaa gcttttggtg ctagatgttg 550

 attatacatt atttgaccac aggtcttgtg cagagactgg ggtagaatta 600

 atgcggccat atcttcatga atttctaaca tctgcctatg aagattatga 650

 cattgttatt tggtctgcaa caaatatgaa gtggattgaa gctaaaatga 700

 aagagctggg agtgagcaca aatgcaaatt ataagattac tttcatgttg 750

 gatagtgctg ctatgataac agtacatact ccaaggagag gattaataga 800

 cgtaaagcct cttggtgtta tatggggaaa gttttcggag ttttacagca 850

 agaaaaacac cattatgttt gatgacatag ggagaaattt tctaatgaac 900

 ccacagaatg gactaaagat aaggcctttt atgaaagcgc acctaaatcg 950

 tgataaagac aaagaacttt taaaattaac tcagtacctc aaggagatag 1000

 caaaattaga tgactttttg gatctaaatc acaaatattg ggaaagatat 1050

 ctctcaaaga agcaaggaca gtagttacaa gttatactgg cagttattga 1100

 agatacttaa gatccaagaa cttcttgctt ttatgctaga aatcattatg 1150

 atagtgctgg acactgaagc aaataccata ctgcttatac ttggtcttcc 1200

 agttttttgt aagtttaatt ttatattttt tgaagatgat agcaatatgc 1250

 taaaaaatgc ttgtccccta tatgaatatt ctgttacgct tgaaaaatat 1300

 tttctccagc gttggttact gaccacccca ccctcccacc acacacacac 1350

 acacacacac acacacacac acacacacac acacacacaa agtggagaaa 1400

 aatgtatact caacaatgtc attttgtgac tttggaaaca agttatgttt 1450

 tgtgtttttg tctcattgtg ttattgtctg actaaatcta aaaccaaacc 1500

 catgttgaaa ctagtacttt tccctttaaa aacaaaccaa aaaaaaaaaa 1550

 caaaaaaaaa ctttttaatt aaagaaccta gtttgctatg cttaaaatta 1600

 ccaagaattt tttatttctt tgtcatagac acaatttctc ttctgtatgc 1650

 cactagttac atttctaaat tctgagcggt ctcagttagg cctgtatgtg 1700

 tgtacatgtc caagtaaagc tggaaaatgt cagtcttgac acagctgtgt 1750

 cttagtatga gaaacagaag actgaagaat aaaaactaag gaacaagaat 1800

 gagtctcttt ttggtggcta agtagaatct tcctaaaacc attgtcataa 1850

 aagcagttaa aggcaataaa tttttaaaag ggacatatca ctgattcatt 1900

 cctaaaaagc atgaacaaaa agtttttgtt ctgttccagc tatatcttgt 1950

 ctaagtgcta acactgtttc agtgaaaata tctagccata agattaaaaa 2000

 aatatattat ttgcaatgct taagcctgca gatacgtaat gtgaccactg 2050

 ttttgtgttg acaatattgc tttatacagt tcttgtattt gaaaggaatt 2100

 gatcctttta aagaaacatg gtgtatattg ttcttacagg actaatttca 2150

 gtggtgtaaa taataaatat cttttctg 2178

<210> 4522
<211> 318
<212> PRT
<213> Homo sapien

<400> 4522
 Met Ala Leu Pro Ile Ile Val Lys Trp Gly Gly Gln Glu Tyr Ser
   1               5                  10                  15

 Val Thr Thr Leu Ser Glu Asp Asp Thr Val Leu Asp Leu Lys Gln
                  20                  25                  30

 Phe Leu Lys Thr Leu Thr Gly Val Leu Pro Glu Arg Gln Lys Leu
                  35                  40                  45

 Leu Gly Leu Lys Val Lys Gly Lys Pro Ala Glu Asn Asp Val Lys
                  50                  55                  60

 Leu Gly Ala Leu Lys Leu Lys Pro Asn Thr Lys Ile Met Met Met
                  65                  70                  75

 Gly Thr Arg Glu Glu Ser Leu Gly Asp Val Leu Gly Pro Pro Pro
                  80                  85                  90

 Asp Asn Asp Asp Val Val Asn Asp Phe Asp Ile Glu Asp Glu Val
                  95                 100                 105

 Val Glu Val Glu Asn Arg Glu Glu Asn Leu Leu Lys Ile Ser Arg
                 110                 115                 120

 Arg Val Lys Glu Tyr Lys Val Glu Ile Leu Asn Pro Pro Arg Glu
                 125                 130                 135

 Gly Lys Lys Leu Leu Val Leu Asp Val Asp Tyr Thr Leu Phe Asp
                 140                 145                 150

 His Arg Ser Cys Ala Glu Thr Gly Val Glu Leu Met Arg Pro Tyr
                 155                 160                 165

 Leu His Glu Phe Leu Thr Ser Ala Tyr Glu Asp Tyr Asp Ile Val
                 170                 175                 180

 Ile Trp Ser Ala Thr Asn Met Lys Trp Ile Glu Ala Lys Met Lys
                 185                 190                 195

 Glu Leu Gly Val Ser Thr Asn Ala Asn Tyr Lys Ile Thr Phe Met
                 200                 205                 210

 Leu Asp Ser Ala Ala Met Ile Thr Val His Thr Pro Arg Arg Gly
                 215                 220                 225

 Leu Ile Asp Val Lys Pro Leu Gly Val Ile Trp Gly Lys Phe Ser
                 230                 235                 240

 Glu Phe Tyr Ser Lys Lys Asn Thr Ile Met Phe Asp Asp Ile Gly
                 245                 250                 255

 Arg Asn Phe Leu Met Asn Pro Gln Asn Gly Leu Lys Ile Arg Pro
                 260                 265                 270

 Phe Met Lys Ala His Leu Asn Arg Asp Lys Asp Lys Glu Leu Leu
                 275                 280                 285

 Lys Leu Thr Gln Tyr Leu Lys Glu Ile Ala Lys Leu Asp Asp Phe
                 290                 295                 300

 Leu Asp Leu Asn His Lys Tyr Trp Glu Arg Tyr Leu Ser Lys Lys
                 305                 310                 315

 Gln Gly Gln


<210> 4523
<211> 8564
<212> DNA
<213> Homo sapien

<400> 4523
 ggggcgggga ggctggcgga gagtcggtgg tgcgggatgc cccgcctccg 50

 ggccgcgtcc gttctccacg gctggtacct gtgtcgggtg ggtggccagg 100

 cggggctcgc ccccagcccc ctcgccaggg ctagccgact gcgcggcgcc 150

 cggaggggac agatcaccgg taggggccgc ggctagattc cgcgctggag 200

 aacgccctct cgcggctccc tggcccggcc accgcgctcc ctctccccgc 250

 ccagagggcc ccggggcacc atgcaggcgc agcagctgcc ctacgagttt 300

 ttcagcgaag agaacgcgcc caagtggcgg ggactactgg tgcctgcgct 350

 gaaaaaggtc caggggcaag ttcatcctac tctcgagtct aatgatgatg 400

 ctcttcagta tgttgaagaa ttaattttgc aattattaaa tatgctatgc 450

 caagctcagc cccgaagtgc ttcagatgta gaggaacgtg ttcaaaaaag 500

 tttccctcat ccaattgata aatgggcaat agctgatgcc caatcagcta 550

 ttgaaaagag gaagcgaaga aaccctttat ctctcccagt agaaaaaatt 600

 catcctttat taaaggaggt cctaggttat aaaattgacc accaggtttc 650

 tgtttacata gtagcagtct tagaatacat ttctgcagac attttaaagc 700

 tggttgggaa ttatgtaaga aatatacggc attatgaaat tacaaaacaa 750

 gatattaaag tggcaatgtg tgctgacaag gtattgatgg atatgtttca 800

 tcaagatgta gaagatatta atatattatc tttaactgac gaagagcctt 850

 ccacctcagg agaacaaact tactatgatt tggtaaaagc atttatggca 900

 gaaattcgac aatatataag ggaactaaat ctaattataa aagtttttag 950

 agagcccttt gtctccaatt caaaattgtt ttcagctaat gatgtagaaa 1000

 atatatttag tcgcatagta gatatacatg aacttagtgt aaagttactg 1050

 ggccatatag aagatacagt agaaatgaca gatgaaggca gtccccatcc 1100

 actagtagga agctgctttg aagacttagc agaggaactg gcatttgatc 1150

 catatgaatc gtatgctcga gatattttgc gacctggttt tcatgatcgt 1200

 ttccttagtc agttatcaaa gcctggggca gcactttatt tgcagtcaat 1250

 aggcgaaggt ttcaaagaag ctgttcaata tgttttaccc aggctgcttc 1300

 tggcccctgt ttaccactgt ctccattact ttgaactttt gaagcagtta 1350

 gaagaaaaaa gtgaagatca agaagacaag gaatgtttaa aacaagcaat 1400

 aacagctttg cttaatgttc agagtggtat ggaaaaaata tgttctaaaa 1450

 gtcttgcaaa acgaagactg agtgaatctg catgtcggtt ttatagtcag 1500

 caaatgaagg ggaaacaact agcaatcaag aagatgaacg agattcagaa 1550

 gaatattgat ggttgggagg gaaaagacat tggacagtgt tgtaatgaat 1600

 ttataatgga aggaactctt acacgtgtag gagccaaaca tgagagacac 1650

 atatttctct ttgatggctt aatgatttgc tgtaaatcaa atcatgggca 1700

 gccaagactt cctggtgcta gcaatgcaga atatcgtctt aaagaaaagt 1750

 tttttatgcg aaaggtacaa attaatgata aagatgacac caatgaatac 1800

 aagcatgctt ttgaaataat tttaaaagat gaaaatagtg ttatattttc 1850

 tgccaagtca gctgaagaga aaaacaattg gatggcagca ttgatatctt 1900

 tacagtaccg gagtacactg gaaaggatgc ttgatgtaac aatgctacag 1950

 gaagagaaag aggagcagat gaggctgcct agtgctgatg tttatagatt 2000

 tgcagagcct gactctgaag agaatattat atttgaagag aacatgcagc 2050

 ccaaggctgg aattccaatt atcaaagcag gaactgttat taaacttata 2100

 gagaggctta cgtaccatat gtacgcagat cccaattttg ttcggacatt 2150

 tcttacaaca tacagatcct tttgcaaacc tcaagaacta ctgagtctta 2200

 taatagaaag gtttgaaatt ccagagcctg agccaacaga agctgatcgc 2250

 atagctatag agaatggaga tcaacccttg agtgcagaac tgaaaagatt 2300

 tagaaaagaa tatatacagc ctgtgcaact gcgagtatta aatgtatgtc 2350

 ggcactgggt agagcaccac ttctatgatt ttgaaagaga tgcatatctt 2400

 ttgcaacgaa tggaagaatt tattggaaca gtaagaggta aagcaatgaa 2450

 aaaatgggtt gaatccatca ctaaaataat ccaaaggaaa aaaattgcaa 2500

 gagacaatgg accaggtcat aatattacat ttcagagttc acctcccaca 2550

 gttgagtggc atataagcag acctgggcac atagagactt ttgacctgct 2600

 caccttacac ccaatagaaa ttgctcgaca actcacttta cttgaatcag 2650

 atctataccg agctgtacag ccatcagaat tagttggaag tgtgtggaca 2700

 aaagaagaca aagaaattaa ctctcctaat cttctgaaaa tgattcgaca 2750

 taccaccaac ctcactctgt ggtttgagaa atgtattgta gaaactgaaa 2800

 atttagaaga aagagtagct gtggtgagtc gaattattga gattctacaa 2850

 gtctttcaag agttgaacaa ctttaatggt gtccttgagg ttgtcagtgc 2900

 tatgaattca tcacctgttt acagactaga ccacacattt gagcaaatac 2950

 caagtcgcca gaagaaaatt ttagaagaag ctcatgaatt gagtgaagat 3000

 cactataaga aatatttggc aaaactcagg tctattaatc caccatgtgt 3050

 gcctttcttt ggaatttatc tcactaatat cttgaaaaca gaagaaggca 3100

 accctgaggt cctaaaaaga catggaaaag agcttataaa ctttagcaaa 3150

 aggaggaaag tagcagaaat aacaggagag atccagcagt accaaaatca 3200

 gccttactgt ttacgagtag aatcagatat caaaaggttc tttgaaaact 3250

 tgaatccgat gggaaatagc atggagaagg aatttacaga ttatcttttc 3300

 aacaaatccc tagaaataga accacgaaac cctaagcctc tcccaagatt 3350

 tccaaaaaaa tatagctatc ccctaaaatc tcctggtgtt cgtccatcaa 3400

 acccaagacc aggtaccatg aggcatccca cacctctgca gcaggagcca 3450

 aggaaaatta gttatagtag gatccctgaa agtgaaacag aaagtacagc 3500

 atctgcacca aattctccaa gaacaccgtt aacacctccg cctgcttctg 3550

 gtgcttccag taccacagat gtttgcagtg tatttgattc cgatcattcg 3600

 agcccttttc actcaagcaa tgataccgtc tttatccaag ttactctgcc 3650

 ccatggccca agatctgctt ctgtatcatc tataagttta accaaaggca 3700

 ctgatgaagt gcctgtccct cctcctgttc ctccacgaag acgaccagaa 3750

 tctgccccag cagaatcttc accatctaag attatgtcta agcatttgga 3800

 cagtccccca gccattcctc ctaggcaacc cacatcaaaa gcctattcac 3850

 cacgatattc aatatcagac cggacctcta tctcagaccc tcctgaaagc 3900

 cctcccttat taccaccacg agaacctgtg aggacacctg atgttttctc 3950

 aagctcacca ctacatctcc aacctccccc tttgggcaaa aaaagtgacc 4000

 atggcaatgc cttcttccca aacagccctt ccccctttac accacctcct 4050

 cctcaaacac cttctcctca cggcacaaga aggcatctgc catcaccacc 4100

 attgacacaa gaagtggacc ttcattccat tgctgggccg cctgttcctc 4150

 cacgacaaag cacttctcaa catatcccta aactccctcc aaaaacttac 4200

 aaaagggagc acacacaccc atccatgcac agagatggac caccactgtt 4250

 ggagaatgcc cattcttcct gagttcctct gtactgggat gtatattttc 4300

 ctagccccaa atccattgct ggcaatggat gcactgaatg tgccagcact 4350

 gaggagttaa aatgagaact ccaaacacta acgactcttc ttcaagatgc 4400

 agtataagac aatgaatttt aacctagatg taattataca atggaaatgg 4450

 tattccagtt tagaatatgg aaagaccgac ctagaggaat tggacaactg 4500

 attgcacctg aaaatcataa agggactttt tctggccaat aggcaggagt 4550

 cctctttttg tgaagtgatc ttttgtgaag tgatcattaa agggatggaa 4600

 aacacagtct agtgtccagc aggcccacat gacagttttt gtaattcaaa 4650

 ttatgcactt ttaaaaaaaa acaaacttaa acagggatct taatatcttc 4700

 ctttgttttc ctttgcttta ctcttctact ttagaatatt ttcttaaaaa 4750

 tcactcaaag gactgtgagg aaaggctgtg gtacctgacc ttgttgaaat 4800

 caaggcccgg cactgtacta caggcctgtt tacagattat tacggtgaac 4850

 tgaatgggta ccgaggcttc accaaagagg tacttttttg ttgttgttgt 4900

 tgttttagga ataattgtac caattttaag agcattcccc ccacctgtcc 4950

 ccacacaccc aaacaaaatg tggtggtgtt gccttcaaaa aagagaagtt 5000

 ttgtgtcatt aacatgacag aagaactttt taaaaaaaaa taactgtcaa 5050

 ctattctatt tgcatttagg agactgttca tctatgctag attgtcattt 5100

 tccctccttc tcccacagaa gtttactggt agtccatgtc atggctcgta 5150

 gctatccctc taaccatacc atggaaatgc aggcacccaa tgtgaaaagg 5200

 agcacttgct gggcatcact gacaccgctc atgttttaca catagttgag 5250

 taatcagcat atctagaatt atcttgcatt gcctaaatca tatgtatata 5300

 gtgaatgtta tataatatac ctggcaggtc tgttttaatt taattgaata 5350

 aagatacaaa tactttgttt ggctggcata tattaaatta ttatatgaag 5400

 aaaatggttg attcttattt cttttagttg aaaaacacac aaaaacacta 5450

 aacataaaag cacgttttgt ggtacgcctt ggtttctagt tctggatata 5500

 tgtattaatc ttaaagaatg atctaaagtc acagcttggc atataggaag 5550

 atacttggtt agaataggat gggtatcttt taagcagaac tttgtaagta 5600

 agttttaagt tcctaagcaa caagtataca gtttgttaag gtttatattg 5650

 aacattctac cttgcttgag gttttctgct ttatcaaaac tattcataat 5700

 agaacatcta cctgcatcat tactatcata atatggatta ttcataaagc 5750

 gtatgtactg ttcttctgag tctaacaaat actgtgactg aaatgcatgc 5800

 accttgttga agagaaaaca ttttattaat ctccactata atgtctgtga 5850

 aatgtgcagt attccatcct tagagagtta tctggttcat cagcatctgc 5900

 atgtatcctc tgaataatga agcaacattt cagcaattct gttaaccaca 5950

 ccattagaga catttttaga agtgctgcaa catggtggga acctagtact 6000

 ttaataattt cctatgatat ttattagagc ataaaatgta catcacgata 6050

 gtacagtatg tagtccttta agaccagaag gtatgttaac tgcaccatca 6100

 ttaagcagtc tatcctgttt tcttatttat ttgttagaat tgaatccttt 6150

 ctcaatatct gtaccattcc tatgatggta gccattcttc tctttataaa 6200

 atatttcctc tttgaaaagc gtcctaaaac attaatttca aatcccctct 6250

 tggatgcaaa gtgtccctaa gaccatccat tcaacagtat ttatgtgagc 6300

 caacttacta gagccgctac aactaatcat gatagacagt ccagaatctc 6350

 cctggacttt atactgggcc agcctcattg tccctaagat ttctcttttt 6400

 atgtctcatg gattacttct ctttttaatt gccccaggca cattccaaat 6450

 gagaacctgg taaaagtcac attggacccc cttcagtatg tcttcggcta 6500

 atgtgttagc cttcaatata aggtgataac cccttttcaa cctatctagt 6550

 ctataaagag gaaaaattca gatttggagt tctaatccta tttctcccaa 6600

 agggaactat tcttctaccc catggttcta ggagaccact tcactgtgca 6650

 acagttttac atgcattgtg gatggaggat atttttattc tgaactgtta 6700

 catttaggta aaaatatttt ctgcagtggt aactgattag aaaaatgcca 6750

 attggatgcc cttaggtgga ggtgagaaaa tggcatcctt gccttcttct 6800

 caatatgaaa cattaactag ttgacaaatt tatccttgta gaaatgaaaa 6850

 tctatttaat cagggaccag aaatggctga ggagataaat gcatcattac 6900

 aaaattctgc ttttgaatcc tggacattac aagggggtaa atgcagcatg 6950

 actttttgtt aaccacattc caaaatgtgg aacatttctt ttagaaatga 7000

 aaatatttca aggctgatgt attttaagac tacacattat caggaaacat 7050

 acattgagag ttcgcttaat taaaggttgt tgggcatcaa attatgttta 7100

 gtaggttact attctctaac aactcaagga tgctttaatg gatctgaatt 7150

 tgacaaagag catgccacac taatactaca gtcaacaaca gcccagagaa 7200

 caattactat gtcagctgga ggctatatta tgattctaaa ttcttaaagg 7250

 tttttttccc tccataaatc aaaaattacc ttatgtaaac caaaaattag 7300

 ttggtattta tggtcatgat cttaattctc aagtttagct taatcttgta 7350

 tttcattgtt tgtcttctaa tatgacagct taaattcaga tttttaagtg 7400

 actcagcaaa ataggaggag tgtcccaatt tattagtgtt gtacatattg 7450

 aagaaaacct ttttgttcct tcagatttag aaagaaacag tttaaccatt 7500

 tatttcttgg tattctgctg ctgtgaatag gtttacttat tcttttaaca 7550

 tatattgtgt gactacgcaa gtataggtcc tgttgtattg cattaatctt 7600

 taccagtaac taaacatcac aaggttaata ttggtttggc tgaaagaatt 7650

 atgcagtaaa gttatttata agggaacatg atgactttat tcaatatttt 7700

 tcttctttga aacatctcat tactaacttt taagattatt tcataatccc 7750

 ttatacatga gccaatgaaa tattttgagc tctacttaag aagcatgaag 7800

 tctatattat aaacctaaac aacaaaagca cttgtaactt gtttagtaaa 7850

 ttccatgcct tattttccat ttttgacacc gtaaagtgca ttttctgtcg 7900

 actgtgagca aatttccctt ttgcctttaa tgaaaatagt gcattaagta 7950

 gccaattgct gcagaattat aaagcaaatt agctaacagt gggtcacatt 8000

 ggactaccac tcaaagaaac aagatgcata acagatgatg gaaggtacat 8050

 gtggtgtggc ttagggagag cgcacctgtg ccagatgcat gccactttca 8100

 gtagctgcca aatgtgcctt taattaagaa catctctaat ttttttcttc 8150

 agatcaagtc agcatttggg gtcgggattt gggcagggaa ctctggggtg 8200

 caaatatctg gtgaaaccac cagagaattt gtttgtcaaa gtgacatgta 8250

 taattttagt tgagacgtgt ttgtgtatat atgtgtattt gcctttgttt 8300

 agtagcacgg ttatttgcta aaataattgt caaaaaattg ctctgtcggt 8350

 cggtctttga tgtaagaaca aagtgtggtc tatacatcta atatggcctt 8400

 tgtacctaac catgttcata ggtaatcttt gtactctgtg tgcagcagta 8450

 tttggtttgc atttaaagtg aaaataacgg ctgttatttt tctggcatta 8500

 ctaagataaa ctgaaaaata ataaagaaaa atgccttaca tagcccacaa 8550

 gtgtattatt tttg 8564

<210> 4524
<211> 1333
<212> PRT
<213> Homo sapien

<400> 4524
 Met Gln Ala Gln Gln Leu Pro Tyr Glu Phe Phe Ser Glu Glu Asn
   1               5                  10                  15

 Ala Pro Lys Trp Arg Gly Leu Leu Val Pro Ala Leu Lys Lys Val
                  20                  25                  30

 Gln Gly Gln Val His Pro Thr Leu Glu Ser Asn Asp Asp Ala Leu
                  35                  40                  45

 Gln Tyr Val Glu Glu Leu Ile Leu Gln Leu Leu Asn Met Leu Cys
                  50                  55                  60

 Gln Ala Gln Pro Arg Ser Ala Ser Asp Val Glu Glu Arg Val Gln
                  65                  70                  75

 Lys Ser Phe Pro His Pro Ile Asp Lys Trp Ala Ile Ala Asp Ala
                  80                  85                  90

 Gln Ser Ala Ile Glu Lys Arg Lys Arg Arg Asn Pro Leu Ser Leu
                  95                 100                 105

 Pro Val Glu Lys Ile His Pro Leu Leu Lys Glu Val Leu Gly Tyr
                 110                 115                 120

 Lys Ile Asp His Gln Val Ser Val Tyr Ile Val Ala Val Leu Glu
                 125                 130                 135

 Tyr Ile Ser Ala Asp Ile Leu Lys Leu Val Gly Asn Tyr Val Arg
                 140                 145                 150

 Asn Ile Arg His Tyr Glu Ile Thr Lys Gln Asp Ile Lys Val Ala
                 155                 160                 165

 Met Cys Ala Asp Lys Val Leu Met Asp Met Phe His Gln Asp Val
                 170                 175                 180

 Glu Asp Ile Asn Ile Leu Ser Leu Thr Asp Glu Glu Pro Ser Thr
                 185                 190                 195

 Ser Gly Glu Gln Thr Tyr Tyr Asp Leu Val Lys Ala Phe Met Ala
                 200                 205                 210

 Glu Ile Arg Gln Tyr Ile Arg Glu Leu Asn Leu Ile Ile Lys Val
                 215                 220                 225

 Phe Arg Glu Pro Phe Val Ser Asn Ser Lys Leu Phe Ser Ala Asn
                 230                 235                 240

 Asp Val Glu Asn Ile Phe Ser Arg Ile Val Asp Ile His Glu Leu
                 245                 250                 255

 Ser Val Lys Leu Leu Gly His Ile Glu Asp Thr Val Glu Met Thr
                 260                 265                 270

 Asp Glu Gly Ser Pro His Pro Leu Val Gly Ser Cys Phe Glu Asp
                 275                 280                 285

 Leu Ala Glu Glu Leu Ala Phe Asp Pro Tyr Glu Ser Tyr Ala Arg
                 290                 295                 300

 Asp Ile Leu Arg Pro Gly Phe His Asp Arg Phe Leu Ser Gln Leu
                 305                 310                 315

 Ser Lys Pro Gly Ala Ala Leu Tyr Leu Gln Ser Ile Gly Glu Gly
                 320                 325                 330

 Phe Lys Glu Ala Val Gln Tyr Val Leu Pro Arg Leu Leu Leu Ala
                 335                 340                 345

 Pro Val Tyr His Cys Leu His Tyr Phe Glu Leu Leu Lys Gln Leu
                 350                 355                 360

 Glu Glu Lys Ser Glu Asp Gln Glu Asp Lys Glu Cys Leu Lys Gln
                 365                 370                 375

 Ala Ile Thr Ala Leu Leu Asn Val Gln Ser Gly Met Glu Lys Ile
                 380                 385                 390

 Cys Ser Lys Ser Leu Ala Lys Arg Arg Leu Ser Glu Ser Ala Cys
                 395                 400                 405

 Arg Phe Tyr Ser Gln Gln Met Lys Gly Lys Gln Leu Ala Ile Lys
                 410                 415                 420

 Lys Met Asn Glu Ile Gln Lys Asn Ile Asp Gly Trp Glu Gly Lys
                 425                 430                 435

 Asp Ile Gly Gln Cys Cys Asn Glu Phe Ile Met Glu Gly Thr Leu
                 440                 445                 450

 Thr Arg Val Gly Ala Lys His Glu Arg His Ile Phe Leu Phe Asp
                 455                 460                 465

 Gly Leu Met Ile Cys Cys Lys Ser Asn His Gly Gln Pro Arg Leu
                 470                 475                 480

 Pro Gly Ala Ser Asn Ala Glu Tyr Arg Leu Lys Glu Lys Phe Phe
                 485                 490                 495

 Met Arg Lys Val Gln Ile Asn Asp Lys Asp Asp Thr Asn Glu Tyr
                 500                 505                 510

 Lys His Ala Phe Glu Ile Ile Leu Lys Asp Glu Asn Ser Val Ile
                 515                 520                 525

 Phe Ser Ala Lys Ser Ala Glu Glu Lys Asn Asn Trp Met Ala Ala
                 530                 535                 540

 Leu Ile Ser Leu Gln Tyr Arg Ser Thr Leu Glu Arg Met Leu Asp
                 545                 550                 555

 Val Thr Met Leu Gln Glu Glu Lys Glu Glu Gln Met Arg Leu Pro
                 560                 565                 570

 Ser Ala Asp Val Tyr Arg Phe Ala Glu Pro Asp Ser Glu Glu Asn
                 575                 580                 585

 Ile Ile Phe Glu Glu Asn Met Gln Pro Lys Ala Gly Ile Pro Ile
                 590                 595                 600

 Ile Lys Ala Gly Thr Val Ile Lys Leu Ile Glu Arg Leu Thr Tyr
                 605                 610                 615

 His Met Tyr Ala Asp Pro Asn Phe Val Arg Thr Phe Leu Thr Thr
                 620                 625                 630

 Tyr Arg Ser Phe Cys Lys Pro Gln Glu Leu Leu Ser Leu Ile Ile
                 635                 640                 645

 Glu Arg Phe Glu Ile Pro Glu Pro Glu Pro Thr Glu Ala Asp Arg
                 650                 655                 660

 Ile Ala Ile Glu Asn Gly Asp Gln Pro Leu Ser Ala Glu Leu Lys
                 665                 670                 675

 Arg Phe Arg Lys Glu Tyr Ile Gln Pro Val Gln Leu Arg Val Leu
                 680                 685                 690

 Asn Val Cys Arg His Trp Val Glu His His Phe Tyr Asp Phe Glu
                 695                 700                 705

 Arg Asp Ala Tyr Leu Leu Gln Arg Met Glu Glu Phe Ile Gly Thr
                 710                 715                 720

 Val Arg Gly Lys Ala Met Lys Lys Trp Val Glu Ser Ile Thr Lys
                 725                 730                 735

 Ile Ile Gln Arg Lys Lys Ile Ala Arg Asp Asn Gly Pro Gly His
                 740                 745                 750

 Asn Ile Thr Phe Gln Ser Ser Pro Pro Thr Val Glu Trp His Ile
                 755                 760                 765

 Ser Arg Pro Gly His Ile Glu Thr Phe Asp Leu Leu Thr Leu His
                 770                 775                 780

 Pro Ile Glu Ile Ala Arg Gln Leu Thr Leu Leu Glu Ser Asp Leu
                 785                 790                 795

 Tyr Arg Ala Val Gln Pro Ser Glu Leu Val Gly Ser Val Trp Thr
                 800                 805                 810

 Lys Glu Asp Lys Glu Ile Asn Ser Pro Asn Leu Leu Lys Met Ile
                 815                 820                 825

 Arg His Thr Thr Asn Leu Thr Leu Trp Phe Glu Lys Cys Ile Val
                 830                 835                 840

 Glu Thr Glu Asn Leu Glu Glu Arg Val Ala Val Val Ser Arg Ile
                 845                 850                 855

 Ile Glu Ile Leu Gln Val Phe Gln Glu Leu Asn Asn Phe Asn Gly
                 860                 865                 870

 Val Leu Glu Val Val Ser Ala Met Asn Ser Ser Pro Val Tyr Arg
                 875                 880                 885

 Leu Asp His Thr Phe Glu Gln Ile Pro Ser Arg Gln Lys Lys Ile
                 890                 895                 900

 Leu Glu Glu Ala His Glu Leu Ser Glu Asp His Tyr Lys Lys Tyr
                 905                 910                 915

 Leu Ala Lys Leu Arg Ser Ile Asn Pro Pro Cys Val Pro Phe Phe
                 920                 925                 930

 Gly Ile Tyr Leu Thr Asn Ile Leu Lys Thr Glu Glu Gly Asn Pro
                 935                 940                 945

 Glu Val Leu Lys Arg His Gly Lys Glu Leu Ile Asn Phe Ser Lys
                 950                 955                 960

 Arg Arg Lys Val Ala Glu Ile Thr Gly Glu Ile Gln Gln Tyr Gln
                 965                 970                 975

 Asn Gln Pro Tyr Cys Leu Arg Val Glu Ser Asp Ile Lys Arg Phe
                 980                 985                 990

 Phe Glu Asn Leu Asn Pro Met Gly Asn Ser Met Glu Lys Glu Phe
                 995                1000                1005

 Thr Asp Tyr Leu Phe Asn Lys Ser Leu Glu Ile Glu Pro Arg Asn
                1010                1015                1020

 Pro Lys Pro Leu Pro Arg Phe Pro Lys Lys Tyr Ser Tyr Pro Leu
                1025                1030                1035

 Lys Ser Pro Gly Val Arg Pro Ser Asn Pro Arg Pro Gly Thr Met
                1040                1045                1050

 Arg His Pro Thr Pro Leu Gln Gln Glu Pro Arg Lys Ile Ser Tyr
                1055                1060                1065

 Ser Arg Ile Pro Glu Ser Glu Thr Glu Ser Thr Ala Ser Ala Pro
                1070                1075                1080

 Asn Ser Pro Arg Thr Pro Leu Thr Pro Pro Pro Ala Ser Gly Ala
                1085                1090                1095

 Ser Ser Thr Thr Asp Val Cys Ser Val Phe Asp Ser Asp His Ser
                1100                1105                1110

 Ser Pro Phe His Ser Ser Asn Asp Thr Val Phe Ile Gln Val Thr
                1115                1120                1125

 Leu Pro His Gly Pro Arg Ser Ala Ser Val Ser Ser Ile Ser Leu
                1130                1135                1140

 Thr Lys Gly Thr Asp Glu Val Pro Val Pro Pro Pro Val Pro Pro
                1145                1150                1155

 Arg Arg Arg Pro Glu Ser Ala Pro Ala Glu Ser Ser Pro Ser Lys
                1160                1165                1170

 Ile Met Ser Lys His Leu Asp Ser Pro Pro Ala Ile Pro Pro Arg
                1175                1180                1185

 Gln Pro Thr Ser Lys Ala Tyr Ser Pro Arg Tyr Ser Ile Ser Asp
                1190                1195                1200

 Arg Thr Ser Ile Ser Asp Pro Pro Glu Ser Pro Pro Leu Leu Pro
                1205                1210                1215

 Pro Arg Glu Pro Val Arg Thr Pro Asp Val Phe Ser Ser Ser Pro
                1220                1225                1230

 Leu His Leu Gln Pro Pro Pro Leu Gly Lys Lys Ser Asp His Gly
                1235                1240                1245

 Asn Ala Phe Phe Pro Asn Ser Pro Ser Pro Phe Thr Pro Pro Pro
                1250                1255                1260

 Pro Gln Thr Pro Ser Pro His Gly Thr Arg Arg His Leu Pro Ser
                1265                1270                1275

 Pro Pro Leu Thr Gln Glu Val Asp Leu His Ser Ile Ala Gly Pro
                1280                1285                1290

 Pro Val Pro Pro Arg Gln Ser Thr Ser Gln His Ile Pro Lys Leu
                1295                1300                1305

 Pro Pro Lys Thr Tyr Lys Arg Glu His Thr His Pro Ser Met His
                1310                1315                1320

 Arg Asp Gly Pro Pro Leu Leu Glu Asn Ala His Ser Ser
                1325                1330

<210> 4525
<211> 4281
<212> DNA
<213> Homo sapien

<400> 4525
 ggctccttta ttgagaatca atgtcttctc ctaggtaatt gatcacccta 50

 gacccaggga cacccaattc atcgtaatca tcatgaataa tcaaaaagtg 100

 gtagctgtgc tactgcaaga gtgcaagcaa gtgctggatc agctcttgtt 150

 ggaagcgcca gatgtgtcgg aagaggacaa gagcgaggac cagcgctgca 200

 gagctttact ccccagcgag ttaaggaccc tgatccagga ggcaaaggaa 250

 atgaagtggc ccttcgtgcc tgaaaagtgg cagtacaaac aagccgtggg 300

 cccagaggac aaaacaaacc tgaaggatgt gattggcgcc gggttgcagc 350

 agttactggc gtccctgagg gcctccatcc tcgctcggga ctgtgcggct 400

 gcggcggcta ttgtgttctt ggtggaccgg ttcctgtatg ggctcgacgt 450

 ctctggaaaa cttctgcagg tcgccaaagg tctccacaag ttgcagccag 500

 ccacgccaat tgccccgcag gtggttattc gccaagcccg aatctccgtg 550

 aactcaggaa aacttttaaa agcagagtat attctgagca gtctaataag 600

 caacaatgga gcaacgggta cctggctgta cagaaatgaa agtgacaagg 650

 tcctggtgca gtcggtctgt atacagatca gagggcagat tctgcaaaag 700

 ctgggtatgt ggtacgaagc agcagagtta atatgggcct ccattgtagg 750

 atatttggca cttcctcagc cggataaaaa gggcctctcc acgtcgctag 800

 gtatactggc agacatcttt gtttccatga gcaagaacga ttatgaaaag 850

 tttaaaaaca atccacaaat taatttgagc ctgctgaagg agtttgacca 900

 ccatttgctg tccgctgcag aagcctgcaa gctggcagct gccttcagtg 950

 cctatacgcc gctcttcgtg ctcacagctg tgaatatccg tggcacgtgt 1000

 ttattgtcct acagtagttc aaatgactgt cctccagaat tgaaaaactt 1050

 acatctgtgt gaagccaaag aggcctttga gattggcctc ctcaccaaga 1100

 gagatgatga gcctgttact ggaaaacagg agcttcacag ctttgtcaaa 1150

 gctgctttcg gtctcaccac agtgcacaga aggctccatg gggagacagg 1200

 gacggtccat gcagcaagtc agctctgtaa ggaagcaatg gggaagctgt 1250

 acaatttcag cacttcctcc agaagtcagg acagagaagc tctgtctcaa 1300

 gaagttatgt ctgtgattgc ccaggtgaag gaacatttac aagttcaaag 1350

 cttctcaaat gtagatgaca gatcttatgt tcccgagagt ttcgagtgca 1400

 ggttggataa acttatcttg catgggcaag gggatttcca aaaaatcctt 1450

 gacacctatt cacagcacca tacttcggtg tgtgaagtat ttgaaagtga 1500

 ttgtggaaac aacaaaaatg aacagaaaga tgcaaaaaca ggagtctgca 1550

 tcactgctct aaaaacagaa ataaaaaaca tagatactgt gagtactact 1600

 caagaaaagc cacattgtca aagagacaca ggaatatctt cctccctaat 1650

 gggtaagaat gttcagaggg aactcagaag gggaggaagg agaaactgga 1700

 cccattctga tgcatttcga gtctccttgg atcaagatgt ggagactgag 1750

 actgagccat cggactacag caatgatgag ggagctgttt tcaacaagtc 1800

 tctgagtggc agccagactt ccagtgcttg gagcaactta tcagggttta 1850

 gttcctctgc aagctgggag gaagtgaatt atcacgttga cgacaggtca 1900

 gccagaaaag agcctggcaa agaacatctg gtggacactc agtgttccac 1950

 tgccttgtct gaggagctag agaatgacag ggaaggcaga gctatgcatt 2000

 cattgcgttc acagcttcat gatctctctc ttcaggaacc caacaatgac 2050

 aatttggagc cttctcaaaa tcagccacag caacagatgc ccttgacacc 2100

 cttctcgcct cataataccc caggcatttt cttggcccct ggtgcagggc 2150

 ttctagaagg agctccagaa ggtatccagg aagtcagaaa tatgggaccc 2200

 agaaatactt ctgctcactc cagaccctca tatcgttctg cttcttggtc 2250

 ttctgattct ggtaggccca agaatatagg cacacatcct tcagtccaaa 2300

 aagaagaagc ctttgaaata attgttgagt ttccagaaac caactgcgat 2350

 gtcaaagaca ggcaggggaa agagcaggga gaagaaatta gtgaaagagg 2400

 cgcaggccct acatttaaag ctagtccctc ctgggttgac ccagaaggag 2450

 aaacagcaga aagcactgaa gatgcaccct tagactttca cagggtcctg 2500

 cacaattctc tgggaaacat ttccatgctg ccatgtagct ccttcacccc 2550

 taattggcct gttcaaaatc ctgactccag aaaaagtggt ggcccagtcg 2600

 cagagcaggg catcgaccct gatgcctcca cagtggatga ggaggggcaa 2650

 ctgctcgaca gcacggatgt tccctgcaca aatgggcacg gctctcatag 2700

 actgtgcatt ctgagacagc cgcctggtca gagggcggag acccccaatt 2750

 cctctgtaag cggtaacatc ctcttccctg tcctcagcga ggactgcact 2800

 accacagagg aaggaaatca gcctggaaac atgctaaact gcagccagaa 2850

 ctccagctca tcctcagtgt ggtggctgaa atcacctgca ttttccagtg 2900

 gttcttctga gggggacagc ccttggtcct atctgaattc cagtgggagt 2950

 tcttgggttt cattgccggg aaagatgagg aaagagatcc ttgaggctcg 3000

 caccttgcaa cctgatgact ttgaaaagct gttggcagga gtgaggcatg 3050

 attggctgtt tcagagacta gagaatacgg gggtttttaa gcccagtcaa 3100

 ctccaccgag cacatagtgc tcttttgtta aaatattcaa aaaaatctga 3150

 actgtggacg gcccaggaaa ctattgtcta tttgggggac tacttgactg 3200

 tgaagaaaaa aggcagacaa agaaatgctt tttgggttca tcatcttcat 3250

 caagaagaaa ttctggggag gtatgttggg aaagactata aggagcagaa 3300

 ggggctctgg caccacttca ctgatgtgga gcggcagatg accgcacagc 3350

 actatgtgac agaatttaac aagagactct atgaacaaaa cattcccacc 3400

 cagatattct acatcccatc cacaatacta ctgattttag aggacaagac 3450

 aataaaggga tgtatcagtg tggagcctta catactggga gaatttgtaa 3500

 aattgtcaaa taacacgaaa gtggtgaaaa cagaatacaa agccacagaa 3550

 tatggcttgg cctatggcca tttttcttat gagttttcta atcatagaga 3600

 tgttgtggtc gatttacaag gttgggtaac cggtaatgga aaaggactca 3650

 tctacctcac agatccccag attcactccg ttgatcagaa agttttcact 3700

 accaattttg gaaagagagg aattttttac ttctttaata accagcatgt 3750

 ggaatgtaat gaaatctgcc atcgtctttc tttgactaga ccttcaatgg 3800

 agaaaccatg cacatagaat acggcacagt ctggtccttt ggggcttggg 3850

 cagggccgtg acacaggttc tggccaatga tttgcaagag gaattgatca 3900

 gtatcacttt aagtcctgca tttaattggc agcacaagat cctgcagagc 3950

 ctctttccct ctgccacagt tatcaagaat gggtcaggag accgctgctt 4000

 ctgggcataa gtcctgcaag gaaagcaaca tggaaaacag ccccaactca 4050

 cccatgaggg atgaaaagca ctcttgagaa aggcatgtgt tgtttaagcc 4100

 attgagattt tagagctttt tgtcactatc tgtcaagact gatactactg 4150

 gggcttttcc tattgatttg ggagttcttt acatattaaa aaaatgtgag 4200

 cctttgtgat acgaattcaa tttgttttcc tgtcttttga catttgactt 4250

 tgcataaaag tttatctgtg cataatttta a 4281

<210> 4526
<211> 1244
<212> PRT
<213> Homo sapien

<400> 4526
 Met Asn Asn Gln Lys Val Val Ala Val Leu Leu Gln Glu Cys Lys
   1               5                  10                  15

 Gln Val Leu Asp Gln Leu Leu Leu Glu Ala Pro Asp Val Ser Glu
                  20                  25                  30

 Glu Asp Lys Ser Glu Asp Gln Arg Cys Arg Ala Leu Leu Pro Ser
                  35                  40                  45

 Glu Leu Arg Thr Leu Ile Gln Glu Ala Lys Glu Met Lys Trp Pro
                  50                  55                  60

 Phe Val Pro Glu Lys Trp Gln Tyr Lys Gln Ala Val Gly Pro Glu
                  65                  70                  75

 Asp Lys Thr Asn Leu Lys Asp Val Ile Gly Ala Gly Leu Gln Gln
                  80                  85                  90

 Leu Leu Ala Ser Leu Arg Ala Ser Ile Leu Ala Arg Asp Cys Ala
                  95                 100                 105

 Ala Ala Ala Ala Ile Val Phe Leu Val Asp Arg Phe Leu Tyr Gly
                 110                 115                 120

 Leu Asp Val Ser Gly Lys Leu Leu Gln Val Ala Lys Gly Leu His
                 125                 130                 135

 Lys Leu Gln Pro Ala Thr Pro Ile Ala Pro Gln Val Val Ile Arg
                 140                 145                 150

 Gln Ala Arg Ile Ser Val Asn Ser Gly Lys Leu Leu Lys Ala Glu
                 155                 160                 165

 Tyr Ile Leu Ser Ser Leu Ile Ser Asn Asn Gly Ala Thr Gly Thr
                 170                 175                 180

 Trp Leu Tyr Arg Asn Glu Ser Asp Lys Val Leu Val Gln Ser Val
                 185                 190                 195

 Cys Ile Gln Ile Arg Gly Gln Ile Leu Gln Lys Leu Gly Met Trp
                 200                 205                 210

 Tyr Glu Ala Ala Glu Leu Ile Trp Ala Ser Ile Val Gly Tyr Leu
                 215                 220                 225

 Ala Leu Pro Gln Pro Asp Lys Lys Gly Leu Ser Thr Ser Leu Gly
                 230                 235                 240

 Ile Leu Ala Asp Ile Phe Val Ser Met Ser Lys Asn Asp Tyr Glu
                 245                 250                 255

 Lys Phe Lys Asn Asn Pro Gln Ile Asn Leu Ser Leu Leu Lys Glu
                 260                 265                 270

 Phe Asp His His Leu Leu Ser Ala Ala Glu Ala Cys Lys Leu Ala
                 275                 280                 285

 Ala Ala Phe Ser Ala Tyr Thr Pro Leu Phe Val Leu Thr Ala Val
                 290                 295                 300

 Asn Ile Arg Gly Thr Cys Leu Leu Ser Tyr Ser Ser Ser Asn Asp
                 305                 310                 315

 Cys Pro Pro Glu Leu Lys Asn Leu His Leu Cys Glu Ala Lys Glu
                 320                 325                 330

 Ala Phe Glu Ile Gly Leu Leu Thr Lys Arg Asp Asp Glu Pro Val
                 335                 340                 345

 Thr Gly Lys Gln Glu Leu His Ser Phe Val Lys Ala Ala Phe Gly
                 350                 355                 360

 Leu Thr Thr Val His Arg Arg Leu His Gly Glu Thr Gly Thr Val
                 365                 370                 375

 His Ala Ala Ser Gln Leu Cys Lys Glu Ala Met Gly Lys Leu Tyr
                 380                 385                 390

 Asn Phe Ser Thr Ser Ser Arg Ser Gln Asp Arg Glu Ala Leu Ser
                 395                 400                 405

 Gln Glu Val Met Ser Val Ile Ala Gln Val Lys Glu His Leu Gln
                 410                 415                 420

 Val Gln Ser Phe Ser Asn Val Asp Asp Arg Ser Tyr Val Pro Glu
                 425                 430                 435

 Ser Phe Glu Cys Arg Leu Asp Lys Leu Ile Leu His Gly Gln Gly
                 440                 445                 450

 Asp Phe Gln Lys Ile Leu Asp Thr Tyr Ser Gln His His Thr Ser
                 455                 460                 465

 Val Cys Glu Val Phe Glu Ser Asp Cys Gly Asn Asn Lys Asn Glu
                 470                 475                 480

 Gln Lys Asp Ala Lys Thr Gly Val Cys Ile Thr Ala Leu Lys Thr
                 485                 490                 495

 Glu Ile Lys Asn Ile Asp Thr Val Ser Thr Thr Gln Glu Lys Pro
                 500                 505                 510

 His Cys Gln Arg Asp Thr Gly Ile Ser Ser Ser Leu Met Gly Lys
                 515                 520                 525

 Asn Val Gln Arg Glu Leu Arg Arg Gly Gly Arg Arg Asn Trp Thr
                 530                 535                 540

 His Ser Asp Ala Phe Arg Val Ser Leu Asp Gln Asp Val Glu Thr
                 545                 550                 555

 Glu Thr Glu Pro Ser Asp Tyr Ser Asn Asp Glu Gly Ala Val Phe
                 560                 565                 570

 Asn Lys Ser Leu Ser Gly Ser Gln Thr Ser Ser Ala Trp Ser Asn
                 575                 580                 585

 Leu Ser Gly Phe Ser Ser Ser Ala Ser Trp Glu Glu Val Asn Tyr
                 590                 595                 600

 His Val Asp Asp Arg Ser Ala Arg Lys Glu Pro Gly Lys Glu His
                 605                 610                 615

 Leu Val Asp Thr Gln Cys Ser Thr Ala Leu Ser Glu Glu Leu Glu
                 620                 625                 630

 Asn Asp Arg Glu Gly Arg Ala Met His Ser Leu Arg Ser Gln Leu
                 635                 640                 645

 His Asp Leu Ser Leu Gln Glu Pro Asn Asn Asp Asn Leu Glu Pro
                 650                 655                 660

 Ser Gln Asn Gln Pro Gln Gln Gln Met Pro Leu Thr Pro Phe Ser
                 665                 670                 675

 Pro His Asn Thr Pro Gly Ile Phe Leu Ala Pro Gly Ala Gly Leu
                 680                 685                 690

 Leu Glu Gly Ala Pro Glu Gly Ile Gln Glu Val Arg Asn Met Gly
                 695                 700                 705

 Pro Arg Asn Thr Ser Ala His Ser Arg Pro Ser Tyr Arg Ser Ala
                 710                 715                 720

 Ser Trp Ser Ser Asp Ser Gly Arg Pro Lys Asn Ile Gly Thr His
                 725                 730                 735

 Pro Ser Val Gln Lys Glu Glu Ala Phe Glu Ile Ile Val Glu Phe
                 740                 745                 750

 Pro Glu Thr Asn Cys Asp Val Lys Asp Arg Gln Gly Lys Glu Gln
                 755                 760                 765

 Gly Glu Glu Ile Ser Glu Arg Gly Ala Gly Pro Thr Phe Lys Ala
                 770                 775                 780

 Ser Pro Ser Trp Val Asp Pro Glu Gly Glu Thr Ala Glu Ser Thr
                 785                 790                 795

 Glu Asp Ala Pro Leu Asp Phe His Arg Val Leu His Asn Ser Leu
                 800                 805                 810

 Gly Asn Ile Ser Met Leu Pro Cys Ser Ser Phe Thr Pro Asn Trp
                 815                 820                 825

 Pro Val Gln Asn Pro Asp Ser Arg Lys Ser Gly Gly Pro Val Ala
                 830                 835                 840

 Glu Gln Gly Ile Asp Pro Asp Ala Ser Thr Val Asp Glu Glu Gly
                 845                 850                 855

 Gln Leu Leu Asp Ser Thr Asp Val Pro Cys Thr Asn Gly His Gly
                 860                 865                 870

 Ser His Arg Leu Cys Ile Leu Arg Gln Pro Pro Gly Gln Arg Ala
                 875                 880                 885

 Glu Thr Pro Asn Ser Ser Val Ser Gly Asn Ile Leu Phe Pro Val
                 890                 895                 900

 Leu Ser Glu Asp Cys Thr Thr Thr Glu Glu Gly Asn Gln Pro Gly
                 905                 910                 915

 Asn Met Leu Asn Cys Ser Gln Asn Ser Ser Ser Ser Ser Val Trp
                 920                 925                 930

 Trp Leu Lys Ser Pro Ala Phe Ser Ser Gly Ser Ser Glu Gly Asp
                 935                 940                 945

 Ser Pro Trp Ser Tyr Leu Asn Ser Ser Gly Ser Ser Trp Val Ser
                 950                 955                 960

 Leu Pro Gly Lys Met Arg Lys Glu Ile Leu Glu Ala Arg Thr Leu
                 965                 970                 975

 Gln Pro Asp Asp Phe Glu Lys Leu Leu Ala Gly Val Arg His Asp
                 980                 985                 990

 Trp Leu Phe Gln Arg Leu Glu Asn Thr Gly Val Phe Lys Pro Ser
                 995                1000                1005

 Gln Leu His Arg Ala His Ser Ala Leu Leu Leu Lys Tyr Ser Lys
                1010                1015                1020

 Lys Ser Glu Leu Trp Thr Ala Gln Glu Thr Ile Val Tyr Leu Gly
                1025                1030                1035

 Asp Tyr Leu Thr Val Lys Lys Lys Gly Arg Gln Arg Asn Ala Phe
                1040                1045                1050

 Trp Val His His Leu His Gln Glu Glu Ile Leu Gly Arg Tyr Val
                1055                1060                1065

 Gly Lys Asp Tyr Lys Glu Gln Lys Gly Leu Trp His His Phe Thr
                1070                1075                1080

 Asp Val Glu Arg Gln Met Thr Ala Gln His Tyr Val Thr Glu Phe
                1085                1090                1095

 Asn Lys Arg Leu Tyr Glu Gln Asn Ile Pro Thr Gln Ile Phe Tyr
                1100                1105                1110

 Ile Pro Ser Thr Ile Leu Leu Ile Leu Glu Asp Lys Thr Ile Lys
                1115                1120                1125

 Gly Cys Ile Ser Val Glu Pro Tyr Ile Leu Gly Glu Phe Val Lys
                1130                1135                1140

 Leu Ser Asn Asn Thr Lys Val Val Lys Thr Glu Tyr Lys Ala Thr
                1145                1150                1155

 Glu Tyr Gly Leu Ala Tyr Gly His Phe Ser Tyr Glu Phe Ser Asn
                1160                1165                1170

 His Arg Asp Val Val Val Asp Leu Gln Gly Trp Val Thr Gly Asn
                1175                1180                1185

 Gly Lys Gly Leu Ile Tyr Leu Thr Asp Pro Gln Ile His Ser Val
                1190                1195                1200

 Asp Gln Lys Val Phe Thr Thr Asn Phe Gly Lys Arg Gly Ile Phe
                1205                1210                1215

 Tyr Phe Phe Asn Asn Gln His Val Glu Cys Asn Glu Ile Cys His
                1220                1225                1230

 Arg Leu Ser Leu Thr Arg Pro Ser Met Glu Lys Pro Cys Thr
                1235                1240

<210> 4527
<211> 3639
<212> DNA
<213> Homo sapien

<400> 4527
 ctcgaggctc cgcaccagcc gcgcttctgt ccgcctgcag ggcattccag 50

 aaagatgagg atatttgctg tctttatatt catgacctac tggcatttgc 100

 tgaacgcatt tactgtcacg gttcccaagg acctatatgt ggtagagtat 150

 ggtagcaata tgacaattga atgcaaattc ccagtagaaa aacaattaga 200

 cctggctgca ctaattgtct attgggaaat ggaggataag aacattattc 250

 aatttgtgca tggagaggaa gacctgaagg ttcagcatag tagctacaga 300

 cagagggccc ggctgttgaa ggaccagctc tccctgggaa atgctgcact 350

 tcagatcaca gatgtgaaat tgcaggatgc aggggtgtac cgctgcatga 400

 tcagctatgg tggtgccgac tacaagcgaa ttactgtgaa agtcaatgcc 450

 ccatacaaca aaatcaacca aagaattttg gttgtggatc cagtcacctc 500

 tgaacatgaa ctgacatgtc aggctgaggg ctaccccaag gccgaagtca 550

 tctggacaag cagtgaccat caagtcctga gtggtaagac caccaccacc 600

 aattccaaga gagaggagaa gcttttcaat gtgaccagca cactgagaat 650

 caacacaaca actaatgaga ttttctactg cacttttagg agattagatc 700

 ctgaggaaaa ccatacagct gaattggtca tcccagaact acctctggca 750

 catcctccaa atgaaaggac tcacttggta attctgggag ccatcttatt 800

 atgccttggt gtagcactga cattcatctt ccgtttaaga aaagggagaa 850

 tgatggatgt gaaaaaatgt ggcatccaag atacaaactc aaagaagcaa 900

 agtgatacac atttggagga gacgtaatcc agcattggaa cttctgatct 950

 tcaagcaggg attctcaacc tgtggtttag gggttcatcg gggctgagcg 1000

 tgacaagagg aaggaatgga cccgtgggat gcaggcaatg tgggacttaa 1050

 aaggcccaag cactgaaaat ggaacctggc gaaagcagag gaggagaatg 1100

 aagaaagatg gagtcaaaca gggagcctgg agggagacct tgatactttc 1150

 aaatgcctga ggggctcatc gacgcctgtg acagggagaa aggatacttc 1200

 tgaacaagga gcctccaagc aaatcatcca ttgctcatcc taggaagacg 1250

 ggttgagaat ccctaatttg agggtcagtt cctgcagaag tgccctttgc 1300

 ctccactcaa tgcctcaatt tcttttctgc atgactgaga gtctcagtgt 1350

 tggaacggga cagtatttat gtatgagttt ttcctattta ttttgagtct 1400

 gtgaggtctt cttgtcatgt gagtgtggtt gtgaatgatt tcttttgaag 1450

 atatattgta gtagatgtta caattttgtc gccaaactaa acttgctgct 1500

 taatgatttg ctcacatcta gtaaaacatg gagtatttgt aaggtgcttg 1550

 gtctcctcta taactacaag tatacattgg aagcataaag atcaaaccgt 1600

 tggttgcata ggatgtcacc tttatttaac ccattaatac tctggttgac 1650

 ctaatcttat tctcagacct caagtgtctg tgcagtatct gttccattta 1700

 aatatcagct ttacaattat gtggtagcct acacacataa tctcatttca 1750

 tcgctgtaac caccctgttg tgataaccac tattatttta cccatcgtac 1800

 agctgaggaa gcaaacagat taagtaactt gcccaaacca gtaaatagca 1850

 gacctcagac tgccacccac tgtcctttta taatacaatt tacagctata 1900

 ttttacttta agcaattctt ttattcaaaa accatttatt aagtgccctt 1950

 gcaatatcaa tcgctgtgcc agggcattga atctacagat gtgaggcaag 2000

 acaaagtacc tgtcctcaag gagctcatag tataatgagg agattaacaa 2050

 gaaaatgtat tattacaatt tagtccagtg tcatagcata aggatgatgc 2100

 gaggggaaaa cccgagcagt gttgccaaga ggaggaaata ggccaatgtg 2150

 gtctgggacg gttggatata cttaaacatc ttaataatca gagtaatttt 2200

 catttacaaa gagaggtcgg tacttaaaat aaccctgaaa aataacactg 2250

 gaattccttt tctagcatta tatttattcc tgatttgcct ttgccatata 2300

 atctaatgct tgtttatata gtgtctggta ttgtttaaca gttctgtctt 2350

 ttctatttaa atgccactaa attttaaatt catacctttc catgattcaa 2400

 aattcaaaag atcccatggg agatggttgg aaaatctcca cttcatcctc 2450

 caagccattc aagtttcctt tccagaagca actgctactg cctttcattc 2500

 atatgttctt ctaaagatag tctacatttg gaaatgtatg ttaaaagcac 2550

 gtatttttaa aatttttttc ctaaatagta acacattgta tgtctgctgt 2600

 gtactttgct atttttattt attttagtgt ttcttatata gcagatggaa 2650

 tgaatttgaa gttcccaggg ctgaggatcc atgccttctt tgtttctaag 2700

 ttatctttcc catagctttt cattatcttt catatgatcc agtatatgtt 2750

 aaatatgtcc tacatataca tttagacaac caccatttgt taagtatttg 2800

 ctctaggaca gagtttggat ttgtttatgt ttgctcaaaa ggagacccat 2850

 gggctctcca gggtgcactg agtcaatcta gtcctaaaaa gcaatcttat 2900

 tattaactct gtatgacaga atcatgtctg gaacttttgt tttctgcttt 2950

 ctgtcaagta taaacttcac tttgatgctg tacttgcaaa atcacatttt 3000

 ctttctggaa attccggcag tgtaccttga ctgctagcta ccctgtgcca 3050

 gaaaagcctc attcgttgtg cttgaaccct tgaatgccac cagctgtcat 3100

 cactacacag ccctcctaag aggcttcctg gaggtttcga gattcagatg 3150

 ccctgggaga tcccagagtt tcctttccct cttggccata ttctggtgtc 3200

 aatgacaagg agtaccttgg ctttgccaca tgtcaaggct gaagaaacag 3250

 tgtctccaac agagctcctt gtgttatctg tttgtacatg tgcatttgta 3300

 cagtaattgg tgtgacagtg ttctttgtgt gaattacagg caagaattgt 3350

 ggctgagcaa ggcacatagt ctactcagtc tattcctaag tcctaactcc 3400

 tccttgtggt gttggatttg taaggcactt tatccctttt gtctcatgtt 3450

 tcatcgtaaa tggcataggc agagatgata cctaattctg catttgattg 3500

 tcactttttg tacctgcatt aatttaataa aatattctta tttattttgt 3550

 tacttggtac accagcatgt ccattttctt gtttattttg tgtttaataa 3600

 aatgttcagt ttaacatccc agtggagaaa gttaaaaaa 3639

<210> 4528
<211> 308
<212> PRT
<213> Homo sapien

<400> 4528
 Leu Glu Ala Pro His Gln Pro Arg Phe Cys Pro Pro Ala Gly His
   1               5                  10                  15

 Ser Arg Lys Met Arg Ile Phe Ala Val Phe Ile Phe Met Thr Tyr
                  20                  25                  30

 Trp His Leu Leu Asn Ala Phe Thr Val Thr Val Pro Lys Asp Leu
                  35                  40                  45

 Tyr Val Val Glu Tyr Gly Ser Asn Met Thr Ile Glu Cys Lys Phe
                  50                  55                  60

 Pro Val Glu Lys Gln Leu Asp Leu Ala Ala Leu Ile Val Tyr Trp
                  65                  70                  75

 Glu Met Glu Asp Lys Asn Ile Ile Gln Phe Val His Gly Glu Glu
                  80                  85                  90

 Asp Leu Lys Val Gln His Ser Ser Tyr Arg Gln Arg Ala Arg Leu
                  95                 100                 105

 Leu Lys Asp Gln Leu Ser Leu Gly Asn Ala Ala Leu Gln Ile Thr
                 110                 115                 120

 Asp Val Lys Leu Gln Asp Ala Gly Val Tyr Arg Cys Met Ile Ser
                 125                 130                 135

 Tyr Gly Gly Ala Asp Tyr Lys Arg Ile Thr Val Lys Val Asn Ala
                 140                 145                 150

 Pro Tyr Asn Lys Ile Asn Gln Arg Ile Leu Val Val Asp Pro Val
                 155                 160                 165

 Thr Ser Glu His Glu Leu Thr Cys Gln Ala Glu Gly Tyr Pro Lys
                 170                 175                 180

 Ala Glu Val Ile Trp Thr Ser Ser Asp His Gln Val Leu Ser Gly
                 185                 190                 195

 Lys Thr Thr Thr Thr Asn Ser Lys Arg Glu Glu Lys Leu Phe Asn
                 200                 205                 210

 Val Thr Ser Thr Leu Arg Ile Asn Thr Thr Thr Asn Glu Ile Phe
                 215                 220                 225

 Tyr Cys Thr Phe Arg Arg Leu Asp Pro Glu Glu Asn His Thr Ala
                 230                 235                 240

 Glu Leu Val Ile Pro Glu Leu Pro Leu Ala His Pro Pro Asn Glu
                 245                 250                 255

 Arg Thr His Leu Val Ile Leu Gly Ala Ile Leu Leu Cys Leu Gly
                 260                 265                 270

 Val Ala Leu Thr Phe Ile Phe Arg Leu Arg Lys Gly Arg Met Met
                 275                 280                 285

 Asp Val Lys Lys Cys Gly Ile Gln Asp Thr Asn Ser Lys Lys Gln
                 290                 295                 300

 Ser Asp Thr His Leu Glu Glu Thr
                 305

<210> 4529
<211> 3243
<212> DNA
<213> Homo sapien

<400> 4529
 agtagagcct ggtgcctggg agcggctggc gcggcggaat ccagggccga 50

 cccgggccgg accgacccca ggcggcgacg gaatcagtcc ccaatgcctg 100

 gaaattcctc attggattac tgtgttttaa acagaatttc gtgaacagcc 150

 ttttatctcc aagcggaaag aaagatgtgg aaagcttcag caggccacgc 200

 tgtgtccatc gcccaggatg acgcgggggc cgatgactgg gagaccgacc 250

 ctgattttgt gaatgatgtg agtgagaagg agcaaagatg gggtgccaag 300

 acggtgcagg gctccgggca ccaggagcat atcaacatac acaagctgag 350

 ggagaatgtc tttcaagagc atcagaccct taaggagaag gaacttgaaa 400

 caggaccaaa agcttcccat ggctatggag ggaaatttgg tgtggaacaa 450

 gaccgaatgg ataagtcagc tgtcggccac gaatatcagt cgaaactttc 500

 caagcactgc tcgcaggtgg actcggtccg tggcttcgga ggcaagtttg 550

 gtgtccagat ggacagagtt gatcagtctg ctgtaggctt tgaataccag 600

 gggaagactg agaagcatgc ctcccagaaa gactactcca gtggttttgg 650

 cggcaagtat ggcgtgcagg ccgaccgagt agacaagagc gcggtgggct 700

 tcgactacca gggcaagacg gagaagcacg agtcacagag agattactcc 750

 aaaggtttcg gcggcaaata cggtatcgac aaggacaaag tggataagag 800

 cgccgttggc tttgagtatc aaggcaaaac ggagaagcac gagtcccaga 850

 aagactatgt gaaagggttt ggaggaaaat ttggtgtgca gacagacaga 900

 caagacaaat gtgcccttgg ctgggatcac caggagaaat tgcagctgca 950

 tgaatcccaa aaagattata agactggttt tggaggcaaa ttcggtgttc 1000

 agtcggagag gcaggactcc gctgctgtgg ggtttgatta caaggagaag 1050

 ctggccaagc acgagtccca gcaagactac tccaaaggat tcggcgggaa 1100

 gtatggggtg cagaaggatc ggatggataa gaatgcgtca acctttgagg 1150

 atgtcaccca ggtgtcctct gcctaccaga agacagtacc tgtcgaagct 1200

 gtgaccagca aaacaagtaa catcagagct aactttgaaa acctcgctaa 1250

 ggagaaagag caggaggaca ggcggaaggc ggaggcggag agagcccagc 1300

 ggatggccaa ggagcggcag gagcaggaag aggccaggag gaagctggag 1350

 gagcaagcca gagccaaaac gcaaacgccc cctgtgtcgc ccgcacctca 1400

 gccaaccgag gagaggctgc cctcgagccc cgtctatgag gatgcggctt 1450

 ccttcaaggc agagctgagc tacagaggcc ctgtgagtgg gacggagccg 1500

 gagcccgtgt acagcatgga ggccgctgac taccgagagg ccagcagcca 1550

 gcagggcctg gcctatgcca cagaggctgt ctatgaaagc gcagaggccc 1600

 cgggccacta tcccgcagag gacagcacct acgatgagta cgagaacgat 1650

 ctggggatca cagccgtcgc cctgtacgac taccaggctg cgggcgatga 1700

 tgagatctca tttgaccctg atgacatcat caccaacatc gagatgattg 1750

 acgacggctg gtggcgcggg gtgtgcaagg gccggtacgg gctcttccca 1800

 gccaactatg tggagctgcg gcagtagggc ccccagcccc cccccggagc 1850

 tgcgccctgg atcctcacac tacagatcag gccttctttg gttcttgggt 1900

 ggttttgggt tttttctgtt tttttttttt tttttttttt ttgaaggtgg 1950

 ggaggggaat atacacattg cttttatatt taatactttt gctgatgctt 2000

 ttgaaaatgt ttatgccaca gaatttgcta atatattgta atcacattcc 2050

 ttaggaggac tttggtaatt ggttttatgc attgatggtt ttttttttct 2100

 tttttgccaa attgactgtc acgcggcagc ttcagggagc tcgcattctc 2150

 ttgtgttcgt gttgccctcg tgcccatcaa gtgcagtcgg gacctcccag 2200

 gacaagcacg aggcctcagg tcggccctgt ggcgggtagg caggaaggac 2250

 tgtcccagac gaggggcttc ctctagagtc tcactgctgg ggaggagagg 2300

 actgggcctg atggaagtta acccggagct aagtcaccca gagcacagga 2350

 gctgccatgt cagatgggaa atctgcctat gtcataccgt gacagcccgc 2400

 aggatcaggt gacttctagc agagaccctg gtttttttcc tgtgcccact 2450

 ccggcttgtc ctcatctcta cccatcccct gatgcccagg tcaccgggag 2500

 ggctgctggg agcctctcct gtccccgccg ggcagtgtca ctgagtcctt 2550

 gaaatcctcc cctgccccgc gggtctctgg attgggacgc acagtgcagt 2600

 tgaggtctgc gtcgggcttg gcttttcaca aaggctgatg tcttaactgt 2650

 cacccatatg gtccctgggc caccgggcag cctggggcgg tgtgtgtgcc 2700

 atgtcacagc atggcctctc ggccttggga aggaaggcag tgcctgctct 2750

 gctgtgagcc gccaggaacc ctcctcctgt caatgggggt gtagtatttt 2800

 tgccaaaata tcatgttcaa tttcagtagt ttgatcagtt gaaggctaga 2850

 agtgtgaagt gcagatgagt gtgtgttctt ccccaaggtc cccccacagc 2900

 tccaggacac cgctgtcctg gcatttgtgg ccactcactt tgtaggaaac 2950

 tcatctcctt cctgaggagc cgggaggctg gaccagtccc gtcgtgcagt 3000

 caggtgggcg gtgtgtcttt ccagaaggtc acgtggaaat gtctcgggac 3050

 ttgggtcccg gagtgcccgt gaagcgtgtt tttgctcctg aggtgcattt 3100

 tctcatcatc cttgctttac cacaatgagc aatgaggtcg ggttttatat 3150

 gcaacttatt gtatctgaat tcctgtagca cacctcatag gtatgatttt 3200

 tttaaattaa agaattcaga ataaacattt tttgatccaa aaa 3243

<210> 4530
<211> 550
<212> PRT
<213> Homo sapien

<400> 4530
 Met Trp Lys Ala Ser Ala Gly His Ala Val Ser Ile Ala Gln Asp
   1               5                  10                  15

 Asp Ala Gly Ala Asp Asp Trp Glu Thr Asp Pro Asp Phe Val Asn
                  20                  25                  30

 Asp Val Ser Glu Lys Glu Gln Arg Trp Gly Ala Lys Thr Val Gln
                  35                  40                  45

 Gly Ser Gly His Gln Glu His Ile Asn Ile His Lys Leu Arg Glu
                  50                  55                  60

 Asn Val Phe Gln Glu His Gln Thr Leu Lys Glu Lys Glu Leu Glu
                  65                  70                  75

 Thr Gly Pro Lys Ala Ser His Gly Tyr Gly Gly Lys Phe Gly Val
                  80                  85                  90

 Glu Gln Asp Arg Met Asp Lys Ser Ala Val Gly His Glu Tyr Gln
                  95                 100                 105

 Ser Lys Leu Ser Lys His Cys Ser Gln Val Asp Ser Val Arg Gly
                 110                 115                 120

 Phe Gly Gly Lys Phe Gly Val Gln Met Asp Arg Val Asp Gln Ser
                 125                 130                 135

 Ala Val Gly Phe Glu Tyr Gln Gly Lys Thr Glu Lys His Ala Ser
                 140                 145                 150

 Gln Lys Asp Tyr Ser Ser Gly Phe Gly Gly Lys Tyr Gly Val Gln
                 155                 160                 165

 Ala Asp Arg Val Asp Lys Ser Ala Val Gly Phe Asp Tyr Gln Gly
                 170                 175                 180

 Lys Thr Glu Lys His Glu Ser Gln Arg Asp Tyr Ser Lys Gly Phe
                 185                 190                 195

 Gly Gly Lys Tyr Gly Ile Asp Lys Asp Lys Val Asp Lys Ser Ala
                 200                 205                 210

 Val Gly Phe Glu Tyr Gln Gly Lys Thr Glu Lys His Glu Ser Gln
                 215                 220                 225

 Lys Asp Tyr Val Lys Gly Phe Gly Gly Lys Phe Gly Val Gln Thr
                 230                 235                 240

 Asp Arg Gln Asp Lys Cys Ala Leu Gly Trp Asp His Gln Glu Lys
                 245                 250                 255

 Leu Gln Leu His Glu Ser Gln Lys Asp Tyr Lys Thr Gly Phe Gly
                 260                 265                 270

 Gly Lys Phe Gly Val Gln Ser Glu Arg Gln Asp Ser Ala Ala Val
                 275                 280                 285

 Gly Phe Asp Tyr Lys Glu Lys Leu Ala Lys His Glu Ser Gln Gln
                 290                 295                 300

 Asp Tyr Ser Lys Gly Phe Gly Gly Lys Tyr Gly Val Gln Lys Asp
                 305                 310                 315

 Arg Met Asp Lys Asn Ala Ser Thr Phe Glu Asp Val Thr Gln Val
                 320                 325                 330

 Ser Ser Ala Tyr Gln Lys Thr Val Pro Val Glu Ala Val Thr Ser
                 335                 340                 345

 Lys Thr Ser Asn Ile Arg Ala Asn Phe Glu Asn Leu Ala Lys Glu
                 350                 355                 360

 Lys Glu Gln Glu Asp Arg Arg Lys Ala Glu Ala Glu Arg Ala Gln
                 365                 370                 375

 Arg Met Ala Lys Glu Arg Gln Glu Gln Glu Glu Ala Arg Arg Lys
                 380                 385                 390

 Leu Glu Glu Gln Ala Arg Ala Lys Thr Gln Thr Pro Pro Val Ser
                 395                 400                 405

 Pro Ala Pro Gln Pro Thr Glu Glu Arg Leu Pro Ser Ser Pro Val
                 410                 415                 420

 Tyr Glu Asp Ala Ala Ser Phe Lys Ala Glu Leu Ser Tyr Arg Gly
                 425                 430                 435

 Pro Val Ser Gly Thr Glu Pro Glu Pro Val Tyr Ser Met Glu Ala
                 440                 445                 450

 Ala Asp Tyr Arg Glu Ala Ser Ser Gln Gln Gly Leu Ala Tyr Ala
                 455                 460                 465

 Thr Glu Ala Val Tyr Glu Ser Ala Glu Ala Pro Gly His Tyr Pro
                 470                 475                 480

 Ala Glu Asp Ser Thr Tyr Asp Glu Tyr Glu Asn Asp Leu Gly Ile
                 485                 490                 495

 Thr Ala Val Ala Leu Tyr Asp Tyr Gln Ala Ala Gly Asp Asp Glu
                 500                 505                 510

 Ile Ser Phe Asp Pro Asp Asp Ile Ile Thr Asn Ile Glu Met Ile
                 515                 520                 525

 Asp Asp Gly Trp Trp Arg Gly Val Cys Lys Gly Arg Tyr Gly Leu
                 530                 535                 540

 Phe Pro Ala Asn Tyr Val Glu Leu Arg Gln
                 545                 550

<210> 4531
<211> 3709
<212> DNA
<213> Homo sapien

<400> 4531
 caaaaacaca atagaagtcc attatccctt gataattatt tcttaaaagc 50

 aaatgggagt aagtgttctt atctggaaaa ataaataaat aaaatgctca 100

 aagggtatca ccacttcaat tttatcaagc caccttggac aaagtatcca 150

 aattgtggtt gccttaataa actaaaacat tattgtacat aatgtaatta 200

 taaatctatc agtctgcatg gatgcaaact gtgtgtgaca aatcgtcttt 250

 taaatggtca atttcagctg tacatttctc atccaagttg tactctagcc 300

 attggtttag cgtggacaga tactccatct ctattatcca tttccacagc 350

 ccaaataaaa tatgttaagc aggctcagaa tgaatatgaa gaattccatt 400

 tccgtagatg ttttctaaaa gtcagattgt ggaaatttca aataagtatt 450

 ttcaatttcc tccctcactc cctcttacct tccccaagac atcaaacacc 500

 tggcatggta gattatagaa agagacactg agagagagaa ttaaattttc 550

 taatgggaat tagaatatct ggtttacctc caaattaagt ttctttacag 600

 gaagttggga ccagctggaa attgtattat catttcggaa cacaatatta 650

 cttccttaga gagagatgga tttttgttgg caacataaaa gaataagtga 700

 tggggtatct atgtgagtaa atttttaaat tccaagttaa tatgcttgca 750

 aacattactg ctgcgttatg gcaccaagag ttggttgaaa ttacccacgt 800

 agtcatactc ctgtgctctg tcaccatgga cttcacatca tttgctgccc 850

 actagttcaa tcgcatttaa tcctagcaat atgtaagttt aaaggactgc 900

 attcccctct actttaaagc ttatatccta gatactcagt ttgtgacctt 950

 ggttgacctt tggcatttca cgcaagttga acagcaaaat caaagcagcc 1000

 atttttaatt cgtcattccc aagccctatc tgagtggttc caaagtcacc 1050

 tgagaggaag gtttaaatta gtccctctca ccccaccatt gctataaaac 1100

 agcaacgttt tcattccaat tcagccataa agaggtttct cttcttactg 1150

 ggttttgaaa tcatttcctt ttttctttcg tttgcccttc ttccttcctg 1200

 tgttgtacta tctctccaac cacgtctata agcagactca atcttcttgc 1250

 agaggaagat gagctggcac tctgcaaact tctttaataa ggacccaaag 1300

 tttacttgac attaacctct agtaggtgag aaattccaaa aaagctttgg 1350

 ggtacattag aatttccaaa gctctgaaag atatttcagg agatttaaca 1400

 gcagagttgc aacttacacg tgaattctgg tctatagtgg tcatgtgagt 1450

 taaattcgaa tcctctactt gtatgaccct aggaatagat tggaatactg 1500

 cagaggacca aagctgaggc atgctaaaca gctgcttgga ggtggaagca 1550

 agttcagtca cctactcagc ttcctctctc caccacccag ttcctccctc 1600

 agtatcacat tatttttttc ttctgctttt cattaaccta actcatctca 1650

 tcagtacaac cattttctta ttctctaact acccccaatt cctttagcct 1700

 ctccccacct gtccaaactc agctcagccg tgggccaatg cagcttacag 1750

 acggttgcag agctaggaag aaaacccagc tctcccaacc ctgatcgtgg 1800

 aggtctctgg ccccccaaca ctgccttctg ggggctgcat tttttttttt 1850

 ttttgagaag aggtcttttg ggatgcatgg tgctccacat acagcttcac 1900

 aaaatatttc attataagag aaaccccttg atttttattt ctttttcttt 1950

 tgttttctgg attacctgcc ttcagtaagc agatgcagac ccacttgtaa 2000

 ggagtctggt tagtgatgag aaaaggatga aatctagata caaaagtcac 2050

 cttgaaggtg atgatggatc tttaatccac ttgactaagt gtctggaaga 2100

 gctacttgct cttccacccc tcatctcaaa tgagaggagc agaagtttaa 2150

 cttcctcaaa tagcccagct ctggctaaaa cccaaagaag aaaggtcaaa 2200

 ggaagggaaa gcatgtcagg ggctggtttg tgacttggca ggaccaggaa 2250

 acagcagcca ctgacagccc agagaaggtg actaagggct ggcagaagat 2300

 tagaatgtta atttggctgc tgtccggact aggaggccat gttcaatggc 2350

 agtcagaatt tgtgttctgc gcattgctgg gtctataaat atgataagca 2400

 agtggtgaca gaattatagt ataaggtgat gtactacatg cagatcataa 2450

 aggctttggt tttaagactt aagtagaaaa tccctctcct agcttattac 2500

 ccaacaatat tcagataatg agcttttgga gaatatcttt ttcctatcac 2550

 tagaaagatt tacctgggaa ctgtctaaag tctacacaca tatttccaaa 2600

 gcctttaaat accaactgca gcatggagag agaggggtgg cagaagctga 2650

 aatgcctcaa aagccattta agtgttacgt tgcaggattt tcagtccttc 2700

 tcgttatgta aaagtagata aatatagacg ttattctcaa cactacccta 2750

 tagtatcaca gtggtccaaa tgccagagct tacagataat gtcatcacag 2800

 tgcctagaaa ctcgaactgt aatatatcgt agcattttct tggtgtttct 2850

 taaagtttct ttccacaata caaggtcctc tctgcctctt gtttcttgga 2900

 gagttcaccc cactgatgag tcttccttcc ctgttggact cagtcatttg 2950

 gggaacagtc ttagaagcac atatcaacca aggaagaaac ttcctggata 3000

 tctattgccc acttgcccag gtctaataaa cactaaaggg gggaaattga 3050

 aaggagctgc caactggtca acgtggaagg gcggttccac cctagattgg 3100

 tgtctttctt tttcttcctt tttttaaaaa aaatctattt cttaaataat 3150

 aataaatgca catgatgtgt taaatatgta catatatatt tcaaaagaaa 3200

 aaatggggca caagattgtc ttacaagtcg tgctggctaa tttttagttt 3250

 gtattcataa gtggttttta aaagcctttt ttaaagtgta atttgcatgt 3300

 tctactttga ttgtatgtaa acatatttta gaacaaaaaa tgtatttgta 3350

 ttttattgaa tatagaggca agaaaattgt acattgtttg aaatgttcct 3400

 tttgtaacag tttttattca taaagcattt ttgtacattt aaaatgaaca 3450

 tggacttgct gttatttgag gcgtagatac atctagcatg cttactgtca 3500

 tgctcctcca tggtcttaga tgttgggttt taaacatttt tttctaaaag 3550

 aaagctcagt cttttccgct accagatcag gttagcacag tatagagcac 3600

 ttaactatta aaaaaaaaaa gttaatccta ttcatatgtt attcattgtg 3650

 tgaaattaaa gacattcaat tcagtctaaa aaaaaaaaaa aaaaaaaaaa 3700

 aaaaaaaaa 3709

<210> 4532
<211> 27
<212> PRT
<213> Homo sapien

<400> 4532
 Gln Lys His Asn Arg Ser Pro Leu Ser Leu Asp Asn Tyr Phe Leu
   1               5                  10                  15

 Lys Ala Asn Gly Ser Lys Cys Ser Tyr Leu Glu Lys
                  20                  25

<210> 4533
<211> 1571
<212> DNA
<213> Homo sapien

<400> 4533
 aaaaaaaaaa agaaattact ctccataaca gtctatgtta tcaccaacat 50

 atataaaaac atgatttaga tttccatttc aaagttacat tacccgatta 100

 cttccaaata ggtgctaagc aaaaaccccc aatgtattat tgaaccatgg 150

 acttgcacct catgtttaat gtgaatattt atttccatgt ccctcttaac 200

 tggttttttc ttgtcttccc tctagctgta ttgttatttc agatatgtga 250

 tatctgtttt catactcttg cctttccatc atgaatgctt agttatgaac 300

 agagattcct ttgtagagct cataggcagt acagagaggt aagtcttgcc 350

 tcagagggcc ttgtatcttg gtgtagtttt taaatagtgc atagtgtata 400

 gtgtatagtg tacattttgt tttgcacata gtttgttgcc ccgaatgggt 450

 tttttaccaa gccttttttt ctttcatgta tttacagtcc ggagcacaag 500

 attctcttct ttcaaataca atgtaattcg ctttacttta caacactaaa 550

 tctgggcttt gaatttccag tgcattggac tgattggatt gttgggagtt 600

 agaggctgtt ccaaccatcc ttagtttggg agagtggctc cttctgcttg 650

 ttttctaagc gtacagtcaa cgggtgccat ttgtggtatt taacatgtta 700

 ggatgattgt tccaaatgct gagttgtttt atttctagat gtaattagtt 750

 cactttatgt aatattcttc tctcagactg actttaaaaa caaagtttta 800

 tcattttcat tgtatttgta tttattacag agtgttttag ctttgatatt 850

 ctttgtattt tcattcattt gttacatgag ctttatcagt aacatctgta 900

 taaatggttt ttaaaaatta actatgtatg tgcccatgcc gaagtcgagc 950

 aataaaatca atgctgtttg cactgtcaca gcatcaacgt ttttaaagaa 1000

 tattgagttt gtaatgaatc gttttgaaaa catttatggt tggctctatg 1050

 gagggtgaca acatgagtca caaaatgaaa agttcaagaa cacatgccat 1100

 cctgagttga tgcctctgtc atgttgcaga gctcagcttt ctgtctcctc 1150

 gcagagcagg gaaggtgccc gttttctccg gccgtggtga ctgctcagtt 1200

 ggtagtacct gttgggggta ccgcataggt ggatttctga ggggggtcag 1250

 gggctagtgg ggaagagcat cttggtcctg tcaccagtct gcaaccatct 1300

 ttgctataat acatctccgc tctgtagggc aggcctatga caggggctca 1350

 tatttgccag ccctaccttg gtatgtcgag cagtaaaatt ctcaaaatga 1400

 aaaggagaaa tcaattgtat tttttctaga agctgtggat tttaaggttt 1450

 ataattcact actgtattaa tgatagtgga ctaaagtcca gctaactcta 1500

 tggatagaaa aggaatgaat atggtctgtg taagtctaca cagcataggg 1550

 tacaacaaaa gcatgctcac c 1571

<210> 4534
<211> 23
<212> PRT
<213> Homo sapien

<400> 4534
 Met Asp Arg Lys Gly Met Asn Met Val Cys Val Ser Leu His Ser
   1               5                  10                  15

 Ile Gly Tyr Asn Lys Ser Met Leu
                  20

<210> 4535
<211> 1771
<212> DNA
<213> Homo sapien

<400> 4535
 ccgttgcctg gcccagaatg tttttttaaa tcagatgtag catcttcata 50

 aggtaaagcc tgtcacatca gagtaacaaa gctcctggag tacagtgatg 100

 ctagagtaga atgttccaga agtctggcca tagccccagc ttctgaatta 150

 cctgggagag acaagatgct caggttacta ttttttcttt attctgatag 200

 tacagcctct actcagagac cacggtgtgt gtcacacaac cgaggcagct 250

 agggcatatt ctgagggctt tttttttttt tttggtttcc ttaatgattc 300

 tttaacagag taactggatt ggccaaggtc tgattcaaga ggctgtgagg 350

 agagtagaga acaaatagac tttgcctctc agagttcaga gctttaagtt 400

 gtataagcat ggtccatgtc cacctcttgt agacacttat tccttaaaag 450

 tttccatcat gaaaaataat atcatgtcaa aattttataa gcacccagaa 500

 tgtcccagta gtcaaatgta gtgtctttct ccagtctctg ttttcgataa 550

 taaatacctt gctctcaatt taggatgatc gtaaagccta tgttcatgct 600

 gtgagtcatt gtctcccaca gcttttgaaa catcgttctt tgtcttttct 650

 atacaacacc tgattctttg tgcctcagac tcattgctat caggaagaga 700

 ctttgccaag atccaccacc acatttggcc agtagtgtat acacattaaa 750

 gtgagagctg atgaaatcac aatgctctat tttgttccga caatcagtat 800

 gaaggggtag gtcccagttt gccaatgagc aacagcctct gtatgctggt 850

 gtccaagact tacacaaaac aagtgtcagt gcagtcacag cattttcttg 900

 aatgctgttg tgacagactc cagttataaa catctgcgag ccatatggca 950

 caactcatag ctaaagaggc cggtacaggg cacatgcaca gagctttgaa 1000

 gaacatacac aaacctgttg aatcaagtta ctttcctcat cctcagagac 1050

 tttgacaatt cagagctcac agatggcagg gggaattctc aggcttccct 1100

 tcctcctgat tgacactttt taaaggaagt gatgtggaag ttgttctaga 1150

 agttagatgg acagtgggag cacattcgtg agtggggctt gggagagctc 1200

 aaaagtggca ctttgatttt aggctgggca ggcagaagtc tcacagtaaa 1250

 atatatttca ctagacgtcc aaaccaacac tgcattgtag taacctcttc 1300

 tgaagtaact ggttaaatta ataactggtc ccataagtca gggtcaagcc 1350

 acatttataa cccattcggg ccggccatga agggttctga ctcgacattg 1400

 gtatttaaat gctgttactt tcccaatgct tagtagcact tgagacttta 1450

 tttccatcga caaaaactaa gaaggccaca gaagtagcct aacagtcctc 1500

 cctggtcata ctcgtttcaa acaggtctgc ctgtctagac atattcaggc 1550

 aggaggttgc ttgctgctat cttgaaaacc actggaagat tcagcttctt 1600

 ggggacctca gagcccatat tcatatggaa gcccacccat ataagcctca 1650

 cagagcaaat cacagcaatg ttgaagttgt tattttcaag tgcttatttc 1700

 acgacattaa aaaaaatatt ttttcctggt gtattaaaat taaaaataaa 1750

 atcataactt ttgatttaaa a 1771

<210> 4536
<211> 48
<212> PRT
<213> Homo sapien

<400> 4536
 Met Glu Ala His Pro Tyr Lys Pro His Arg Ala Asn His Ser Asn
   1               5                  10                  15

 Val Glu Val Val Ile Phe Lys Cys Leu Phe His Asp Ile Lys Lys
                  20                  25                  30

 Asn Ile Phe Ser Trp Cys Ile Lys Ile Lys Asn Lys Ile Ile Thr
                  35                  40                  45

 Phe Asp Leu


<210> 4537
<211> 1806
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1722
<223> Unknown base

<400> 4537
 taccctagca tgttgatcag gctaaattaa gttcctctct caagccttat 50

 tgatggctca gtgcccatta tattttaact acaggtaaca gcagtttgtc 100

 ctaaatgcat tagtttgcac ttgtccaggt tgtagctctt ttatgcctct 150

 gctttttccc acatggtctt atgagaacat attgcatata ttcccttcag 200

 ctgagcattt caatacccag acaagtgttt gtcattttag gcctcatcac 250

 atacttgaaa ttccaagtcc tttttaaaag aaatgttaag tagctggtgt 300

 tgctactaga tccctggatt attccacttg tccatccata aaagttcctg 350

 tttattctct accttctgtt tctatttcta agccaatgct ttaagacata 400

 acatctgctc cagcctgttc actatccatg tggttttaaa ctcttaactt 450

 tacttcttag cttcatccct gtaagtaagt gctctctacc tcacaggggt 500

 cttatgaggg ggaaaaaata agatgtttaa gggttgtttt aagagagaga 550

 tccttctttt aaagtgattt tatcaaagcc ccttgggtta gaaatgaaaa 600

 actctatagc tatttttttc ctattctcgt tttgctattt ttatttctga 650

 aaagtgatct gtctgaaaag agccttatat ctggttttaa cttctcctca 700

 ttgacccttt tcacagtgaa atctctactt tatccatgct ctgaactttt 750

 tatttatgga gcccaaacta attttcccac aacaaatctc acatactttt 800

 actcctatca ttaaacaaat taatgtcctc cacaaagaaa catctggctc 850

 ttcctacaag aagtcagaag ctaatgaggt ctcactctgg ccctggcaag 900

 atctcacagt gtgccttggt tctccctgtg taaactgagg tagtccggct 950

 attccccagc gcccaggtgt tgtgagtcct aataaatggt gaaaagcatt 1000

 ttgcaaatgt tctgtactat ataaatgcat agtgcctaat atggagagtc 1050

 ttcaagcaaa aatgtgctct agctcaattc agaatactaa ttcacccatt 1100

 gttttcaaaa gaaatgtttt actaacctgt ttttttttct tttgtaaaat 1150

 tagtttctag tcatttgaac tgtttttatt ttgtgtatag aagtgatcaa 1200

 tagtatatat tcttgcttgt cagagaatac ccaagttgta ttgttaaatg 1250

 ttaaaacaat ggggttacat aacagtatag ttggataggg aggaagattc 1300

 tagctcaaaa gttgcaaaat acagaaatac aaagattagc tttgaattgg 1350

 agattgtact ataaatagta gatgttaatg tggtggtttc tagatatata 1400

 ctttattttt aagttacaag aaattgtctt ttatttttgc agttttgaac 1450

 tatatgattc tttacatgtt ttaaataaag tttttatcaa ctaagatttt 1500

 tcatttacat tattatcagt aaattaaaat acatgtaaaa attaacctaa 1550

 ttacatgact ataaaattta aatttaagat ttaaagaaca tcttttatgg 1600

 caactaagtt tctatacttt agtccttttt aaaaagattt taaaaataat 1650

 agtagaaatg cttttatgct tcaaggagca ttggaaaatt tttttaatat 1700

 gatgttactt attattgtaa tnacttacaa tgacttaata cctttttagt 1750

 gaagctacat ttattccact taaataatta ttgcttattc ctgattaatc 1800

 cttagg 1806

<210> 4538
<211> 9
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1722
<223> Unknown amino acid

<400> 4538
 Tyr Pro Ser Met Leu Ile Arg Leu Asn
   1               5

<210> 4539
<211> 3516
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1533-1550, 1654-1827, 2666-2767
<223> Unknown base

<400> 4539
 aggtaggagt cgactcctgt gaggtatggt gctgggtgca gatgcagtgt 50

 ggctctggat agcaccttat ggacaggtaa gaattgggga aagtatggtg 100

 ggaagaatga aatctaagag gtggtctcag cctgtgatgc tttaagagta 150

 gtggacagaa gggatttctg aaattctatt ctgaggcttt aatgttaaca 200

 gcatttatat ttaacgtgac tgctgtgagg ttcattctca ctgttttgct 250

 tgcatctttt gttttctagt tgtgtcccca aggaaggatg agaatagcta 300

 ctgaagtaag ttgaaaattc cctctcaaaa aggtttaaag ccattggatg 350

 tgccacaatg atgacagttt atttgctact cttgagtgct agaatgatga 400

 ggatcttaac caccattatc ttaactgagg cacccaaaat ggtgagttgg 450

 ggaacataga gagtacacct aagttcacat gaagttgttt cttcccaggt 500

 cctaaagagc aagcctaact caagccattg gcacacaggc attagacaga 550

 aagctggaag ttgaaatggt aagtgaaact gtatccaagt aagcaggtaa 600

 ctgggcaaac ttcctacggc acaaatggct ttttagttac ctcctagtgc 650

 tgaatgcatt aaataaatgg cggattcttg tcttgttatg attaataaga 700

 aagtttgtaa atgcagcctg gatgatgata agcaaatgct gactgaacat 750

 gaaggtctta attagctcta actgactaaa ggcatttgtt agttttggca 800

 gggggtgaac actcatctgt ggctattcta agaccactct tatttcttag 850

 gtggagtcca acttgcctgg accagcttaa tggttctggt aagtattaat 900

 gaaaacagta gatagactta atgaaaatgc tgatggtgat atgcttactg 950

 ctgagctaat ggcttaaggc ttggctgatg aatactgact gtattttcct 1000

 tgagcatgtc tggaacagtg tttatgtgtt ttccttgagc atgtttggaa 1050

 cggggtttgt gtaatgatgt tgatcaaatg tctgacctga aatgagcatg 1100

 tagacaaagg taacactgaa gaaccctgtg acagacaact ttgaaaagag 1150

 tttaatgatg tttagcattt taatggaagt cctcatttgt attccagctc 1200

 ctggtaacgt ttttatccat ggatgacttg cttgggtaag gacatgaaga 1250

 cagttcctgt catacctttt aaaggtacat gttttattga tgttaacgtt 1300

 aattgattga gctactgtta gtgatgattt taaaattaaa gcagatggga 1350

 atctctctga gaaagaaaat ggagattaat cttaaactga aacagtagtt 1400

 gggaaatctt ttagaaatcc acctattact acctattggt aaaggagatt 1450

 aaatttctac aggtatggag agtcggcttg actacactgt gtggagcaag 1500

 ttttaaagaa gcaaaggtat agcagttcca agnnnnnnnn nnnnnnnnnn 1550

 agacaagaag tctagctctt gcccagaaag tggagtgcag cggccctatc 1600

 aagttcactg caacctcgtg cctcccaggc ttcaaggaat tctcctggcc 1650

 tcannnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1700

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1800

 nnnnnnnnnn nnnnnnnnnn nnnnnnntca agtctggttt ttaagtgttg 1850

 taaagccgat acaatgatga taacatagtt cagcagacta acgctgatga 1900

 gcaatattaa gtctttcgct cctatctgat gtatctggcg gtaacattct 1950

 agtttatgcc ccgaaaaggg gaatatagcc attctataat gtttggagat 2000

 tttggattac tcctaattgt atgcaagttg tcttactgtg tattgtccct 2050

 taatttcagg actcagaatt catgattgaa gaaatgcagg ttagtttaaa 2100

 ctttgaagga aatttttaag gtggcaaaag gttttggtgg catatacacc 2150

 ttaatctgta gatgggagtg attagctgtt taaaagttaa aatgtgactg 2200

 agaaggaaat tgagtagggc aaattttaaa tgggtattat ttttcatctt 2250

 caaacaggca gacctgttat cctaaactag gtgagtcagc ttttggtaca 2300

 tgtgatgatt ttcagtgtaa ccaatgatgt aatgattctg ccaaatgaaa 2350

 tataatgata tcactgtaaa accgttccat tttgattctg aggttactct 2400

 actaacaagc atcacacatt tgtattttgc cctgattaat atgttggctt 2450

 cgctttcagg gtttttaatg accacaacaa gcaagcatgc agcttactgc 2500

 ttgaaaggtg aggattggaa atgttgggac tattataatt gcagaataca 2550

 tgatgatctc aatccaactt gaactctctc actgattact tgatgacaat 2600

 aaaatatctg atattctgca ttcccatgta gcattttaat tgaagtctgt 2650

 aaatgtggct aaaagnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2700

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2750

 nnnnnnnnnn nnnnnnnagc ctcccagtgg tctttgtaga ctgcctgatg 2800

 gagtctcatg gcacaagaag attaaaacag tgtctccaat tttaataaat 2850

 ttttgcaatc catctggagt gtgtagtgtt tacttaaaaa aggacagtgc 2900

 ttttcatctg ttcattagct gtaagcataa atcacattca aaagctatta 2950

 taactccatg gtatttgctt cattaacact gcagccagtt aaaattttat 3000

 gggtatttta caaggtgtct tatgcattaa agtgcaatat ttcctaattc 3050

 tccatatgag caaattgtca ggtttcatag gcccctgtgc taattggttt 3100

 tgagcttaaa gtattgatgg agctactttg gagaaagtca tgttgagtct 3150

 gaggctggga aaataagtta tagaaaatac tatagaaatg cccaactagt 3200

 gataggcatt aatggaattg ggaaaatcta caatccatag ccatggtgat 3250

 aggtttttgg caagcactaa gtgtttaggg atgccaaaag tgggtataaa 3300

 gggcacaact ggtttaaggc aatctgtccc agggaaacag gaccaagggg 3350

 ccaaaattcc aagatgggtc aaattttaat ttcagtgtca gtacagctgt 3400

 gcttataatg atgtctttgt tagcagtaat ggttttacaa atctgtttct 3450

 gggctaaagc actttagtcc cattaatgat aaaacttcag ttactctctg 3500

 aattttcctt tttttg 3516

<210> 4540
<211> 13
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1533-1550, 1654-1827, 2666-2767
<223> Unknown amino acid

<400> 4540
 Met Ile Lys Leu Gln Leu Leu Ser Glu Phe Ser Phe Phe
   1               5                  10

<210> 4541
<211> 3845
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3011-3032
<223> Unknown base

<400> 4541
 gcggccgcag ccccggccga gcaggcgccg cgggccaagg gccgcccgag 50

 acggtcccca gagagccacc ggaggagcag ctcacctgag agacggagcc 100

 ccggctcgcc cgtgtgcaga gcggacaagg caaaatctca gcaagttcgg 150

 acctctagta caataaggcg aacctcctct ttggatacaa taacaggacc 200

 ttacctcaca ggacagtggc cacgggatcc tcatgttcac tacccttcat 250

 gcatgaaaga caaagctact cagacaccta gctgttgggc agaagagggt 300

 gcagaaaaga ggtcacatca gcgttctgcg tcatggggga gtgctgatca 350

 actaaaagag cagatcgcca aactgaggca gcaactacaa cgcagtaaac 400

 agagtagtcg tcacagtaag gagaaagatc gccagtcacc tcttcatggc 450

 aaccatataa caatcagtca cactcaggct actggatcaa ggtcagttcc 500

 tatgccactg tcaaatatat cagtgccaaa atcatctgtt tcgcgtgtgc 550

 cctgcaatgt agaaggaata agtcctgaat tagaaaaggt attcattaaa 600

 gaaaataatg ggaaggaaga agtatccaag ccgttggaca taccagatgg 650

 tcgaagagct ccacttcctg ctcattaccg gagcagtagt actcgcagca 700

 ttgacactca gactccttct gtccaggagc gcagcagtag ctgcagcagt 750

 cattcaccct gtgtctcccc tttttgtccc ccggaatccc aggatggtag 800

 cccttgctca acagaagatt tgctctatga tcgtgataaa gacagtggga 850

 gtagctcacc gttacccaag tatgcttcat ctcccaaacc aaacaacagc 900

 tacatgttca aacgggagcc cccagaggga tgtgagcgag tgaaggtctt 950

 tgaggaaatg gcgtctcgtc agcctatctc ggcccctctc ttttcatgtc 1000

 ctgacaaaaa caaggttaat ttcatcccaa ccggatcagc tttctgtcct 1050

 gtaaaacttc taggccccct cttacctgct tctgacctta tgctcaagaa 1100

 ctctcctaac tctggccaga gctcagcttt ggcaactctg accgttgagc 1150

 agctctcatc ccgggtttcc tttacgtctc tttctgatga caccagcaca 1200

 gcgggctcca tggaggcctc tgtccagcag ccatcccagc agcagcagct 1250

 cctgcaggaa ctgcagggtg aggaccacat ctctgctcag aactatgtga 1300

 tcatctaaaa aagggggagc tggcctccac cctgtgttcc atggattcgg 1350

 aacaagattt cagacatctg catgagtgac aaactttctg aacaccacca 1400

 ccaccaataa tacttatcag catcataaag tatctcttaa acactgatct 1450

 tggcagggac ggaactccta ttcagcagtt tttgtggaaa gcagtaatgc 1500

 ttgcaaaacg tgtgtgtcat tcagcatttt aagtggagac tatgcatttc 1550

 atagtatatt tgacagatta gtactgtgtc ctgtgttttg ttccagattc 1600

 ttcagtataa ataagctcta tatcaaaaag ttgcctgtct aaatagaaaa 1650

 tgtcttgctg tgttttgtcc tatggaaaat actgtaattc aggattatgt 1700

 ttacaattga tccaggtgtt tgtttctaac ttctgtaata catacaatgc 1750

 aaaaaaaaaa aaaaaaatgg ccacaacagt tgcacagtgc ccaccctatg 1800

 gcctagcttc aggtacttca gttgaagtct aaactcaggt aacttggaat 1850

 gtatatcata ttgggatatt aaatatttca cagctaaaaa gctaaagagg 1900

 gaacatcact cttttgcctt tccttatttt atgcatttcc ctttcctcat 1950

 tacattccac attcttagaa taagaagtgc attcaatcct aggagaatga 2000

 taatcctgga catgggtgaa catgaggaga accagcaaaa tctgtggtgt 2050

 ttgacatcac tttgtcatgt ggttacaagt aaaacaactg ttgcattcac 2100

 tgtttcaaca tgtgtacatg tggctttttt aaaagttcag gtgttgctca 2150

 gtaaaggact gtgacaatgt tgcaaataaa gtgttcagta ctggactgta 2200

 cataaacatt ccacattgtg tgtgatgaaa tttaaagaca agaatgtcta 2250

 gagttaattt caaaataagt gaagtgtttg acggaatggt tgagattttt 2300

 ttgtttatgt tagccatcag ggtcataact gttaccattt tatctaaaga 2350

 catatttata tttagtttct cccttggaaa ttctttattt tgcaggtgaa 2400

 aaagtgacat actttttgtt attgtcttcc tcaagcagtt taggtgcatg 2450

 atcttcattt acatagaata cttgggtctc agaattgatg caacataagc 2500

 aggttttttt ggtgacttac aagagcaata gtttgaagct atctcattta 2550

 agcctctcat aatgcataat catgagtagt tttgaaattt gcaacctgtg 2600

 aggtagagca taaactcaag aaaatagcct tgaacttgca gacttttgac 2650

 acaagttctc cacaaagtgt gaagagagcc ccaggcattc ctgattggtc 2700

 aatgggagag cctaactttc attgttttct tcagtacaaa gagtatccaa 2750

 aagctaagtt tttgtattcc actactttca gttcaataaa acctagagtt 2800

 gtttcatctg cgcctaaagt gtatggcaca attttcttaa gaattagggg 2850

 aaccaggtgc ctacagttaa aggaacgttt cagttccttt cattcattcc 2900

 tgggtttttc ttttattttc taagaaggtt gaagaaggat gagtgataga 2950

 gaagaaagca acaccattga tttttttttt taagaaatga tatatatatg 3000

 tatatgtttg nnnnnnnnnn nnnnnnnnnn nnagtattct gtgcattatt 3050

 ttgtcatgat ctcaattctc ttctttccac caaagtttgt cgtaatattt 3100

 tctcctgaag gtgcattctg gctcctttaa attagtcagt gttatattgt 3150

 aggagactgt catggaaaaa aggactcagt ttactttcgt cattttcaca 3200

 ggggaacctt ttaaaacaat cttttcagca gcagatacct ttaaccctaa 3250

 taatctcagg ccttgatgaa aatactatat tttgtagatt atggttaaag 3300

 ggggaaaatt actagttccg taagataaat atgagctcca tttgacttct 3350

 gatgtctggt ttagcattac ataatatgtt gatcttacac tctgcttttg 3400

 tccaaataaa atgcaatagt atcaatatca atttcagaaa aatggactga 3450

 atatgctttt ttggtgatga aatctcatgt acgatattta tagtgatgtg 3500

 cttttatttt ctcatgagat actaaatatt aattgtgttg tacatttgtt 3550

 cttagcatat attaaagttt tgaaccaaat gtgttaaagc ttacgctttg 3600

 ccatgtaaat ttcccagaag ttgttgagct caaatgtatc ctacatccag 3650

 ctgtagaaat ttgtcagaaa ttgtttaaat tttgtatata attgtactgt 3700

 ttaattctag ccattgcgct gaacagtatt tgagttacca tataatatgg 3750

 ctttacacaa ggaaatgtgt ggcttttgtt ttgtattttt tcagtataga 3800

 agttcctgtg tcttatttaa ataaagttat tagtaaaact gaaaa 3845

<210> 4542
<211> 435
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3011-3032
<223> Unknown amino acid

<400> 4542
 Ala Ala Ala Ala Pro Ala Glu Gln Ala Pro Arg Ala Lys Gly Arg
   1               5                  10                  15

 Pro Arg Arg Ser Pro Glu Ser His Arg Arg Ser Ser Ser Pro Glu
                  20                  25                  30

 Arg Arg Ser Pro Gly Ser Pro Val Cys Arg Ala Asp Lys Ala Lys
                  35                  40                  45

 Ser Gln Gln Val Arg Thr Ser Ser Thr Ile Arg Arg Thr Ser Ser
                  50                  55                  60

 Leu Asp Thr Ile Thr Gly Pro Tyr Leu Thr Gly Gln Trp Pro Arg
                  65                  70                  75

 Asp Pro His Val His Tyr Pro Ser Cys Met Lys Asp Lys Ala Thr
                  80                  85                  90

 Gln Thr Pro Ser Cys Trp Ala Glu Glu Gly Ala Glu Lys Arg Ser
                  95                 100                 105

 His Gln Arg Ser Ala Ser Trp Gly Ser Ala Asp Gln Leu Lys Glu
                 110                 115                 120

 Gln Ile Ala Lys Leu Arg Gln Gln Leu Gln Arg Ser Lys Gln Ser
                 125                 130                 135

 Ser Arg His Ser Lys Glu Lys Asp Arg Gln Ser Pro Leu His Gly
                 140                 145                 150

 Asn His Ile Thr Ile Ser His Thr Gln Ala Thr Gly Ser Arg Ser
                 155                 160                 165

 Val Pro Met Pro Leu Ser Asn Ile Ser Val Pro Lys Ser Ser Val
                 170                 175                 180

 Ser Arg Val Pro Cys Asn Val Glu Gly Ile Ser Pro Glu Leu Glu
                 185                 190                 195

 Lys Val Phe Ile Lys Glu Asn Asn Gly Lys Glu Glu Val Ser Lys
                 200                 205                 210

 Pro Leu Asp Ile Pro Asp Gly Arg Arg Ala Pro Leu Pro Ala His
                 215                 220                 225

 Tyr Arg Ser Ser Ser Thr Arg Ser Ile Asp Thr Gln Thr Pro Ser
                 230                 235                 240

 Val Gln Glu Arg Ser Ser Ser Cys Ser Ser His Ser Pro Cys Val
                 245                 250                 255

 Ser Pro Phe Cys Pro Pro Glu Ser Gln Asp Gly Ser Pro Cys Ser
                 260                 265                 270

 Thr Glu Asp Leu Leu Tyr Asp Arg Asp Lys Asp Ser Gly Ser Ser
                 275                 280                 285

 Ser Pro Leu Pro Lys Tyr Ala Ser Ser Pro Lys Pro Asn Asn Ser
                 290                 295                 300

 Tyr Met Phe Lys Arg Glu Pro Pro Glu Gly Cys Glu Arg Val Lys
                 305                 310                 315

 Val Phe Glu Glu Met Ala Ser Arg Gln Pro Ile Ser Ala Pro Leu
                 320                 325                 330

 Phe Ser Cys Pro Asp Lys Asn Lys Val Asn Phe Ile Pro Thr Gly
                 335                 340                 345

 Ser Ala Phe Cys Pro Val Lys Leu Leu Gly Pro Leu Leu Pro Ala
                 350                 355                 360

 Ser Asp Leu Met Leu Lys Asn Ser Pro Asn Ser Gly Gln Ser Ser
                 365                 370                 375

 Ala Leu Ala Thr Leu Thr Val Glu Gln Leu Ser Ser Arg Val Ser
                 380                 385                 390

 Phe Thr Ser Leu Ser Asp Asp Thr Ser Thr Ala Gly Ser Met Glu
                 395                 400                 405

 Ala Ser Val Gln Gln Pro Ser Gln Gln Gln Gln Leu Leu Gln Glu
                 410                 415                 420

 Leu Gln Gly Glu Asp His Ile Ser Ala Gln Asn Tyr Val Ile Ile
                 425                 430                 435

<210> 4543
<211> 1634
<212> DNA
<213> Homo sapien

<400> 4543
 ccctgctaac aaagggagcc acttccttcc tctctgcaca taccccatgt 50

 ctcaccacga tgatggagct acagtgggac ttggaatcca gatgtgtgaa 100

 ggatggaggg ttgaagccgc actcagcttc ctgccccacc agaggaagtg 150

 gggagagacg gcaggtgcag tgatggctgg cggagtcatg gacaaggagt 200

 acgtgggttt tgctgccctc cccaaccagc tgcaccgcaa gtctgtcaag 250

 aaggggtttg acttcacgct aatggtggca ggggagtcag gcctagggaa 300

 atccaccctc atcaacagcc tcttcctcac caacctctat gaggatcgcc 350

 aggtgccaga ggccagtgct cgcttgacac agaccctggc cattgagcgc 400

 cggggcgtag agattgagga agggggtgtg aaagtgaagc tgacccttgt 450

 ggacacacct ggctttgggg actcagtgga ctgctctgac tgctggcttc 500

 cggtggtgaa attcatcgag gagcaatttg agcagtacct tagggatgag 550

 agtggcctga accggaagaa catccaggac tcccgagtcc actgctgcct 600

 ctacttcatc tcacccttcg gccgggggct ccggccccta gatgtggcct 650

 tcctccgggc agtacacgag aaagtcaaca tcatcccagt cattggcaaa 700

 gcggatgctc tgatgcccca ggaaacccag gccctcaagc agaagatccg 750

 ggatcagttg aaggaagagg agatccacat ctaccagttc cccgaatgtg 800

 actctgatga agatgaagac ttcaagaggc aggatgcaga gatgaaggaa 850

 agcatccctt ttgcagtcgt gggatcatgc gaggtggtga gggatggcgg 900

 gaaccggccg gtgaggggac gccgctactc ctgggggacc gtggaggtgg 950

 agaacccaca tcactgcgat ttcctgaacc tgcgacggat gctggtgcag 1000

 acacacctgc aggacctgaa agaggtgacg cacgatctgc tctacgaggg 1050

 ctaccgggcc cgctgcctac agagcctggc ccggcctggg gctcgcgatc 1100

 gagccagccg cagtaagctt tcccgccaga gcgccacaga gatcccgctg 1150

 cccatgctgc ctctggcgga caccgagaag ctgatccgcg agaaagacga 1200

 agagctgcgc cgcatgcaag agatgctgga gaagatgcag gcccaaatgc 1250

 agcagagcca ggcccagggc gagcagtcag acgccctctg aggccacgcc 1300

 ccgcccggcc ttacctcggc tccgccttca gtcggcctct tgtccaatcc 1350

 ccgcgcccca cactgcccag cgccccccgg gacctccgcg ggtgccgccc 1400

 tcgcgcgggc tagggggagg ttctcccagc ctgagtccgt agccccgccc 1450

 cggcgctggt cccgcccacc cagacaccgc ccacttcccg gcccggggcc 1500

 tgcacaatct ccgaccgcat cactgtcttc cggagtcccc cttcttctcc 1550

 cagactctgt cttcaataaa aactgagctt cccgcggcca aaaaaaaaaa 1600

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1634

<210> 4544
<211> 367
<212> PRT
<213> Homo sapien

<400> 4544
 Met Asp Lys Glu Tyr Val Gly Phe Ala Ala Leu Pro Asn Gln Leu
   1               5                  10                  15

 His Arg Lys Ser Val Lys Lys Gly Phe Asp Phe Thr Leu Met Val
                  20                  25                  30

 Ala Gly Glu Ser Gly Leu Gly Lys Ser Thr Leu Ile Asn Ser Leu
                  35                  40                  45

 Phe Leu Thr Asn Leu Tyr Glu Asp Arg Gln Val Pro Glu Ala Ser
                  50                  55                  60

 Ala Arg Leu Thr Gln Thr Leu Ala Ile Glu Arg Arg Gly Val Glu
                  65                  70                  75

 Ile Glu Glu Gly Gly Val Lys Val Lys Leu Thr Leu Val Asp Thr
                  80                  85                  90

 Pro Gly Phe Gly Asp Ser Val Asp Cys Ser Asp Cys Trp Leu Pro
                  95                 100                 105

 Val Val Lys Phe Ile Glu Glu Gln Phe Glu Gln Tyr Leu Arg Asp
                 110                 115                 120

 Glu Ser Gly Leu Asn Arg Lys Asn Ile Gln Asp Ser Arg Val His
                 125                 130                 135

 Cys Cys Leu Tyr Phe Ile Ser Pro Phe Gly Arg Gly Leu Arg Pro
                 140                 145                 150

 Leu Asp Val Ala Phe Leu Arg Ala Val His Glu Lys Val Asn Ile
                 155                 160                 165

 Ile Pro Val Ile Gly Lys Ala Asp Ala Leu Met Pro Gln Glu Thr
                 170                 175                 180

 Gln Ala Leu Lys Gln Lys Ile Arg Asp Gln Leu Lys Glu Glu Glu
                 185                 190                 195

 Ile His Ile Tyr Gln Phe Pro Glu Cys Asp Ser Asp Glu Asp Glu
                 200                 205                 210

 Asp Phe Lys Arg Gln Asp Ala Glu Met Lys Glu Ser Ile Pro Phe
                 215                 220                 225

 Ala Val Val Gly Ser Cys Glu Val Val Arg Asp Gly Gly Asn Arg
                 230                 235                 240

 Pro Val Arg Gly Arg Arg Tyr Ser Trp Gly Thr Val Glu Val Glu
                 245                 250                 255

 Asn Pro His His Cys Asp Phe Leu Asn Leu Arg Arg Met Leu Val
                 260                 265                 270

 Gln Thr His Leu Gln Asp Leu Lys Glu Val Thr His Asp Leu Leu
                 275                 280                 285

 Tyr Glu Gly Tyr Arg Ala Arg Cys Leu Gln Ser Leu Ala Arg Pro
                 290                 295                 300

 Gly Ala Arg Asp Arg Ala Ser Arg Ser Lys Leu Ser Arg Gln Ser
                 305                 310                 315

 Ala Thr Glu Ile Pro Leu Pro Met Leu Pro Leu Ala Asp Thr Glu
                 320                 325                 330

 Lys Leu Ile Arg Glu Lys Asp Glu Glu Leu Arg Arg Met Gln Glu
                 335                 340                 345

 Met Leu Glu Lys Met Gln Ala Gln Met Gln Gln Ser Gln Ala Gln
                 350                 355                 360

 Gly Glu Gln Ser Asp Ala Leu
                 365

<210> 4545
<211> 2499
<212> DNA
<213> Homo sapien

<400> 4545
 ggcgggcgtg ggggcagttc cccagcccag gtcctcctct cacccgggcc 50

 agttttcaag gcgggctgta actggtggca tttgtcccgg gaccaggtcc 100

 acagttttat gtgtgagcaa gatggaggct gacctgtctg gctttaacat 150

 cgatgccccc cgttgggacc agcgcacctt cctggggaga gtgaagcact 200

 tcctaaacat cacggacccc cgcactgtct ttgtatctga gcgggagctg 250

 gactgggcca aggtgatggt ggagaagagc aggatggggg ttgtgccccc 300

 aggcacccaa gtggagcagc tgctgtatgc caagaagctg tatgactcgg 350

 ccttccaccc cgacactggg gagaagatga atgtcatcgg gcgcatgtct 400

 ttccagcttc ctggcggcat gatcatcacg ggcttcatgc tccagttcta 450

 caggacgatg ccggcggtga tcttctggca gtgggtgaac cagtccttca 500

 atgccttagt caactacacc aacaggaatg cggcttcccc cacatcagtc 550

 aggcagatgg ccctttccta cttcacagcc acaaccactg ctgtggccac 600

 ggctgtgggc atgaacatgt tgacaaagaa agcgccgccc ttggtgggcc 650

 gctgggtgcc ctttgccgct gtggctgcgg ctaactgtgt caatatcccc 700

 atgatgcgac agcaggagct cataaaggga atctgcgtga aggacaggaa 750

 tgaaaatgag attggtcatt cccggagagc tgcagccata ggcatcaccc 800

 aagtagttat ttctcggatc accatgtcag ctcctgggat gatcttgctg 850

 ccagtcatca tggaaaggct tgagaaattg cacttcatgc agaaagtcaa 900

 ggtcctgcac gccccattgc aggtcatgct gagcgggtgc ttcctcatct 950

 tcatggtgcc agtggcgtgt gggcttttcc cacagaaatg tgaattgcca 1000

 gtttcctatc tggaaccgaa gctccaagac actatcaagg ccaagtatgg 1050

 agaacttgag ccttatgtct acttcaataa gggtctctaa atgccccact 1100

 tcagcaagga ccagtctatt cccatattca ccagctcctc cttagctacg 1150

 tgcacacttg tgtcctcctt cccctttgcc aacaaggcct gaaggccagg 1200

 gtagattggg gggtgggaca atgaatgcct catacttaca ccctggtact 1250

 ggttgattgg acctcagggg aaaaaagtga aaaagggtag caaaggccaa 1300

 tgtcttctag ctgcttcctc aacccctgtc ccctggagac cagaagctga 1350

 ggccctctca gggaggagac atccaagcaa atcatttgga aaagttagga 1400

 aacctttagg attctggttc cagccagggt tgaggaaaag accttggatc 1450

 aaaaggaagc ttctatacct ctttcttctt cgcttcctcc tctcccaagc 1500

 aatggaaact tttacccatg taattctagc tgaactcagg aaaaagaagg 1550

 gggaaaggac tctgtcccct tggggctcat cacccttcca catcctcctc 1600

 ctcgttgccc cctggtcagg cagcttcttt tttttttttt tcaagatgga 1650

 gtcttgctct gtcgcccagg ctggaatgca gtggcgcgat ctcggctcac 1700

 tgcaaactct gcctcctgga ttcaagcgat tctcctgcct cagcctctca 1750

 agtagctggg attacagggc acctgccacc acgcctggct aatttttgta 1800

 ttttagtgga gacggggttt caccatgctg gccagactgg tctcgaactc 1850

 ctgacctcag gtgatccgcc cgcctcagcc tctgaaattg ctgggattac 1900

 aggcatgagc caccacaccc agcccggaca gcttctttgg gagtgctgct 1950

 aaccttgaaa ttatcagaca cttaggagtt attagtgcta aaaaggggac 2000

 cgtgcaaggc agcagagtta catggttctt caaatcatgt ctgaacctat 2050

 tcttggaatc ttctctataa taagggaagt tctcttaccc cactgccaca 2100

 tacctctgtt ttaaaagata agtccactaa ctgtgagtaa aaatgatata 2150

 tataggcatt aaccacacac tttaatgggt ataatttcct ggctgcctcc 2200

 cctcctcagc ccattaggtt aaacaccaaa gaaagactgg tgtgtactga 2250

 ataggaaagg gaagttttat ttggaacctt ctaagaggaa atcaaccagg 2300

 accaaagagc cttaaaggac acacagcaat gcacagccac ttcccttccc 2350

 cagcttggct gccctaggtg atttctcaag ctccttgggg gactgttgtt 2400

 tctcatctgg aatcaatgtg tgtatgagtt ttgtctggta ggattgctga 2450

 ctctgtccaa cagatatccc tgtgaattga ataaatttgt tgaaagagc 2499

<210> 4546
<211> 322
<212> PRT
<213> Homo sapien

<400> 4546
 Met Glu Ala Asp Leu Ser Gly Phe Asn Ile Asp Ala Pro Arg Trp
   1               5                  10                  15

 Asp Gln Arg Thr Phe Leu Gly Arg Val Lys His Phe Leu Asn Ile
                  20                  25                  30

 Thr Asp Pro Arg Thr Val Phe Val Ser Glu Arg Glu Leu Asp Trp
                  35                  40                  45

 Ala Lys Val Met Val Glu Lys Ser Arg Met Gly Val Val Pro Pro
                  50                  55                  60

 Gly Thr Gln Val Glu Gln Leu Leu Tyr Ala Lys Lys Leu Tyr Asp
                  65                  70                  75

 Ser Ala Phe His Pro Asp Thr Gly Glu Lys Met Asn Val Ile Gly
                  80                  85                  90

 Arg Met Ser Phe Gln Leu Pro Gly Gly Met Ile Ile Thr Gly Phe
                  95                 100                 105

 Met Leu Gln Phe Tyr Arg Thr Met Pro Ala Val Ile Phe Trp Gln
                 110                 115                 120

 Trp Val Asn Gln Ser Phe Asn Ala Leu Val Asn Tyr Thr Asn Arg
                 125                 130                 135

 Asn Ala Ala Ser Pro Thr Ser Val Arg Gln Met Ala Leu Ser Tyr
                 140                 145                 150

 Phe Thr Ala Thr Thr Thr Ala Val Ala Thr Ala Val Gly Met Asn
                 155                 160                 165

 Met Leu Thr Lys Lys Ala Pro Pro Leu Val Gly Arg Trp Val Pro
                 170                 175                 180

 Phe Ala Ala Val Ala Ala Ala Asn Cys Val Asn Ile Pro Met Met
                 185                 190                 195

 Arg Gln Gln Glu Leu Ile Lys Gly Ile Cys Val Lys Asp Arg Asn
                 200                 205                 210

 Glu Asn Glu Ile Gly His Ser Arg Arg Ala Ala Ala Ile Gly Ile
                 215                 220                 225

 Thr Gln Val Val Ile Ser Arg Ile Thr Met Ser Ala Pro Gly Met
                 230                 235                 240

 Ile Leu Leu Pro Val Ile Met Glu Arg Leu Glu Lys Leu His Phe
                 245                 250                 255

 Met Gln Lys Val Lys Val Leu His Ala Pro Leu Gln Val Met Leu
                 260                 265                 270

 Ser Gly Cys Phe Leu Ile Phe Met Val Pro Val Ala Cys Gly Leu
                 275                 280                 285

 Phe Pro Gln Lys Cys Glu Leu Pro Val Ser Tyr Leu Glu Pro Lys
                 290                 295                 300

 Leu Gln Asp Thr Ile Lys Ala Lys Tyr Gly Glu Leu Glu Pro Tyr
                 305                 310                 315

 Val Tyr Phe Asn Lys Gly Leu
                 320

<210> 4547
<211> 4052
<212> DNA
<213> Homo sapien

<400> 4547
 gaagtataag tgggattttc accaaaaccc tatccttccc cagactccag 50

 tgacagttta acggtcagct gcatcaaggc ttgtgtactg tgcagtctta 100

 aaaggcacca ctcctgtcca tctcggtgaa attgatggtg gagcaaaagg 150

 gagtttaggt ggttccggtc tggggagaag acgtgcaggg tttcagatgc 200

 gaaagtcgca cccaaccgct tcactcgggc tctaggccat ccgcaggggc 250

 cctgcttcct tccacctgcg agctttttct gcagaatgcg ggaagccgcc 300

 gccgccgcca cagaggaggg ggcggaggca gaggcggagg cggcacccag 350

 gggccggggc aggggaggcc gggaccatcg cagtgacaat ttattttcct 400

 gcagcagcgg cagcagggac ggttgctgca ggttcggggt cggccggcct 450

 gcgcgtgggc ttgcgaggac gctgttcgtc ccctgcgctg gggtgtccga 500

 cagcgaggag gagaacgacg cacggagccc gcgcgactgg aaccagcaaa 550

 gctccatctg tcggcagagg agaaggggga ggaggcacgg ccgaggcaaa 600

 cgagcggacg cctcgtcgcc gggtgccggt atcaccccgc tgcaacgcct 650

 tccagcaaaa gccaccgcgg cccgggttgc agcagccgga cggatgccaa 700

 ggccacacgg cagccacggg ggcagccgtc gcagtcgccg tcccacacgg 750

 gctgcggaca ccaagggttg ctaatgaagt gattgagaag aaacagtgaa 800

 catcctcatt tcacagataa gacaacatgg atcagccttt tactgtgaat 850

 tctctgaaaa agttagctgc tatgcctgac catacagatg tttccctaag 900

 cccagaagag cgagtccgtg ccctaagcaa gcttggttgt aatatcacca 950

 tcagtgaaga catcactcca cgacgttact ttaggtctgg agtagagatg 1000

 gagaggatgg cgtctgtgta tttggaagaa ggaaatttgg aaaatgcctt 1050

 tgttctttat aataaattta taaccttatt tgtagaaaag cttcctaacc 1100

 atcgagatta ccagcaatgt gcagtacctg aaaagcagga tattatgaag 1150

 aaactgaagg agattgcatt cccaaggaca gatgaattga aaaacgacct 1200

 tttaaagaaa tataacgtag aataccaaga atatttgcaa agcaaaaaca 1250

 aatataaagc tgaaattctc aaaaaattgg agcatcagag attgatagag 1300

 gcagaaagga agcggattgc tcagatgcgc cagcagcagc tagaatcgga 1350

 gcagtttctg tttttcgaag atcaactcaa gaagcaagag ttagcccgag 1400

 gtcaaatgcg aagtcagcaa acctcagggc tgtcagagca gattgatggg 1450

 agcgctttgt cctgcttttc cacacaccag aacaattcct tgctgaatgt 1500

 atttgcagat caacctaata aaagtgatgc aaccaattat gctagccact 1550

 ctcctcctgt aaacagggcc ttaacgccag ctgctactct aagtgctgtt 1600

 cagaatttag tggttgaagg actgcgatgt gtagttttgc cagaagatct 1650

 ttgccacaaa tttctgcaac tggcagaatc taatacagtg agaggaatag 1700

 aaacctgtgg aatactctgt ggaaaactga cacataatga atttactatt 1750

 acccatgtaa ttgtgccaaa gcagtctgcg ggaccagact attgtgacat 1800

 ggagaatgta gaggaattat tcaatgttca ggatcaacat gatctcctca 1850

 ctctaggatg gatccataca catcccactc aaactgcatt tttatccagc 1900

 gttgatcttc acactcactg ttcctatcaa ctcatgttgc cagaggccat 1950

 tgccattgtt tgctcaccaa agcataaaga cactggcatc ttcaggctca 2000

 ccaatgctgg catgcttgag gtttctgctt gtaaaaaaaa gggctttcat 2050

 ccacacacca aggagcccag gctgttcagt attcagaaat tcctttctgg 2100

 gataatttct ggcactgctt tggagatgga gcccctgaaa attggctatg 2150

 gaccaaatgg attcccactc ttggggatct ctaggtcatc atcaccatct 2200

 gaacagctct gagagagaca agaagtggaa tggagaaggt gattaggtaa 2250

 tccaagaatt gccaggcgaa caattgtgaa aatctttcat agagttcccg 2300

 atgaaaacaa ctctttcttg ttagccatta tctctgcctt tcctttctaa 2350

 agaaaaacac gtcatttcat cttgattatc agtttctcaa gtactcatgg 2400

 atgtgaggcc aggtaccctg tcaccttggc tctgtttggg atgcaatgtt 2450

 gtgtttgtca ccacttccca ttccccaaaa gcatctttaa catagaccat 2500

 tcattcttca gattcaaaat gcttaagctg aactaacctc aaagggccct 2550

 cattaattta cagacatttg aataacaccc atattcattt ctgctactga 2600

 accaaagcct tttccaaaaa aatcatctag caaactgttt ttgccaggcc 2650

 aaatattaac aggtatatat atttgcatac ataaatattt acctctatgt 2700

 cttgtgtgtt tttgttatga gacagagtct cactctgtcg cccaggctgg 2750

 agtgcagtgg cacagtctca gctcactgca acctccacct cccaggttca 2800

 agcgattctc atgcctcagc ctcccgagta gcgaggacta caggcgtgca 2850

 ccaccacgcc cagctaattt ttgtattttt agtagagatg gggttttacc 2900

 ctgttggcca gggtggtctc gaattcctga cctctgatga tctgcccgcc 2950

 tggacctctc aaagtgctgg gattacagac atgagccact gtgccctgcc 3000

 tctgttttgt gtatttacat aaatacatgt ctccagagct ttaaattctt 3050

 cttaaatttt aaaactagaa ctaaaccaga cattgagagg acccagaaat 3100

 ataccctgac taacgtgggt ggaatttcat ttggcttgac tctttggtga 3150

 aaaaaaaaaa aatcaggctc tcaaggactc aatttggtga accaatgcca 3200

 aatagaaaaa tgttcttgac attttcccca aaatagatgt ctaaagattt 3250

 tgcacttcaa attggtactt tatgtattaa aagtgatatt gaaactaaat 3300

 tcctacccaa ttagttgaaa aatatgaaaa aagcaattgc tagagaatgc 3350

 aatttattaa atgttggtgg tcttttaaaa aatgaattcc tcttgtagcc 3400

 agtgagatca gttatttatt tatttatttt aatagtaaca aggtctcact 3450

 atattgtcca ggctgatctt gaactcctgg cctcaagctg tcctcccatc 3500

 tcagcttccc aaagtgctga gattataggc atgagccacc atgcctggct 3550

 agttaatggt tattaagtaa tacaaacatt tctgtgaatt ccaccagatc 3600

 attgactttg gcatagttca cttaagactt tgtttgataa aataaatctc 3650

 tttcactcta attaggaagc atttttggga tcctgattaa tgctctaata 3700

 ttgtggggcc aaaaaatatg tggaacgtgg ccctgcagtt agatgagctg 3750

 agatcactat agtactatat agcgctctaa atcctaaatg ctagatcact 3800

 gtaatactgt acagatcagc cacttgctgg cttgtgactc tgggccattt 3850

 acttcacctc tcaaaaggca tatttaaagt gaggaaaata ataagtttat 3900

 tttggaaatt cagttagatg atgcaaattg tttactgtaa tttctagcat 3950

 gtagttcgtg ctccatgcat ttaactgtta ttacaggttg tattagtatc 4000

 acattaaatt acccactgaa gtgaaagtga aaccagaatg ctgtcaacga 4050

 tt 4052

<210> 4548
<211> 463
<212> PRT
<213> Homo sapien

<400> 4548
 Asp Asn Met Asp Gln Pro Phe Thr Val Asn Ser Leu Lys Lys Leu
   1               5                  10                  15

 Ala Ala Met Pro Asp His Thr Asp Val Ser Leu Ser Pro Glu Glu
                  20                  25                  30

 Arg Val Arg Ala Leu Ser Lys Leu Gly Cys Asn Ile Thr Ile Ser
                  35                  40                  45

 Glu Asp Ile Thr Pro Arg Arg Tyr Phe Arg Ser Gly Val Glu Met
                  50                  55                  60

 Glu Arg Met Ala Ser Val Tyr Leu Glu Glu Gly Asn Leu Glu Asn
                  65                  70                  75

 Ala Phe Val Leu Tyr Asn Lys Phe Ile Thr Leu Phe Val Glu Lys
                  80                  85                  90

 Leu Pro Asn His Arg Asp Tyr Gln Gln Cys Ala Val Pro Glu Lys
                  95                 100                 105

 Gln Asp Ile Met Lys Lys Leu Lys Glu Ile Ala Phe Pro Arg Thr
                 110                 115                 120

 Asp Glu Leu Lys Asn Asp Leu Leu Lys Lys Tyr Asn Val Glu Tyr
                 125                 130                 135

 Gln Glu Tyr Leu Gln Ser Lys Asn Lys Tyr Lys Ala Glu Ile Leu
                 140                 145                 150

 Lys Lys Leu Glu His Gln Arg Leu Ile Glu Ala Glu Arg Lys Arg
                 155                 160                 165

 Ile Ala Gln Met Arg Gln Gln Gln Leu Glu Ser Glu Gln Phe Leu
                 170                 175                 180

 Phe Phe Glu Asp Gln Leu Lys Lys Gln Glu Leu Ala Arg Gly Gln
                 185                 190                 195

 Met Arg Ser Gln Gln Thr Ser Gly Leu Ser Glu Gln Ile Asp Gly
                 200                 205                 210

 Ser Ala Leu Ser Cys Phe Ser Thr His Gln Asn Asn Ser Leu Leu
                 215                 220                 225

 Asn Val Phe Ala Asp Gln Pro Asn Lys Ser Asp Ala Thr Asn Tyr
                 230                 235                 240

 Ala Ser His Ser Pro Pro Val Asn Arg Ala Leu Thr Pro Ala Ala
                 245                 250                 255

 Thr Leu Ser Ala Val Gln Asn Leu Val Val Glu Gly Leu Arg Cys
                 260                 265                 270

 Val Val Leu Pro Glu Asp Leu Cys His Lys Phe Leu Gln Leu Ala
                 275                 280                 285

 Glu Ser Asn Thr Val Arg Gly Ile Glu Thr Cys Gly Ile Leu Cys
                 290                 295                 300

 Gly Lys Leu Thr His Asn Glu Phe Thr Ile Thr His Val Ile Val
                 305                 310                 315

 Pro Lys Gln Ser Ala Gly Pro Asp Tyr Cys Asp Met Glu Asn Val
                 320                 325                 330

 Glu Glu Leu Phe Asn Val Gln Asp Gln His Asp Leu Leu Thr Leu
                 335                 340                 345

 Gly Trp Ile His Thr His Pro Thr Gln Thr Ala Phe Leu Ser Ser
                 350                 355                 360

 Val Asp Leu His Thr His Cys Ser Tyr Gln Leu Met Leu Pro Glu
                 365                 370                 375

 Ala Ile Ala Ile Val Cys Ser Pro Lys His Lys Asp Thr Gly Ile
                 380                 385                 390

 Phe Arg Leu Thr Asn Ala Gly Met Leu Glu Val Ser Ala Cys Lys
                 395                 400                 405

 Lys Lys Gly Phe His Pro His Thr Lys Glu Pro Arg Leu Phe Ser
                 410                 415                 420

 Ile Gln Lys Phe Leu Ser Gly Ile Ile Ser Gly Thr Ala Leu Glu
                 425                 430                 435

 Met Glu Pro Leu Lys Ile Gly Tyr Gly Pro Asn Gly Phe Pro Leu
                 440                 445                 450

 Leu Gly Ile Ser Arg Ser Ser Ser Pro Ser Glu Gln Leu
                 455                 460

<210> 4549
<211> 2010
<212> DNA
<213> Homo sapien

<400> 4549
 gcagcggcag cagggacggt tgctgcaggt tcggggtcgg ccggcctgcg 50

 cgtgggcttg cgaggacgct gttcgtcccc tgcgctgggg tgtccgacag 100

 cgaggaggag aacgacgcac ggagcccgcg cgactggaac cagcaaagct 150

 ccatctgtcg gcagaggaga agggggagga ggcacggccg aggcaaacga 200

 gcggacgcct cgtcgccggg tgccggtatc accccgctgc aacgccttcc 250

 agcaaaagcc accgcggccc gggttgcagc agccggacgg atgccaaggc 300

 cacacggcag ccacgggggc agccgtcgca gtcgccgtcc cacacgggct 350

 gcggacacca agggttgcta atgaagtgat tgagaagaaa cagtgaacat 400

 cctcatttca cagataagac aacatggatc agccttttac tgtgaattct 450

 ctgaaaaagt tagctgctat gcctgaccat acagatgttt ccctaagccc 500

 agaagagcga gtccgtgccc taagcaagct tggttgtaat atcaccatca 550

 gtgaagacat cactccacga cgttacttta ggtctggagt agagatggag 600

 aggatggcgt ctgtgtattt ggaagaagga aatttggaaa atgcctttgt 650

 tctttataat aaatttataa ccttatttgt agaaaagctt cctaaccatc 700

 gagattacca gcaatgtgca gtacctgaaa agcaggatat tatgaagaaa 750

 ctgaaggaga ttgcattccc aaggacagat gaattgaaaa acgacctttt 800

 aaagaaatat aacgtagaat accaagaata tttgcaaagc aaaaacaaat 850

 ataaagctga aattctcaaa aaattggagc atcagagatt gatagaggca 900

 gaaaggaagc ggattgctca gatgcgccag cagcagctag aatcggagca 950

 gtttctgttt ttcgaagatc aactcaagaa gcaagagtta gcccgaggtc 1000

 aaatgcgaag tcagcaaacc tcagggctgt cagagcagat tgatgggagc 1050

 gctttgtcct gcttttccac acaccagaac aattccttgc tgaatgtatt 1100

 tgcagatcaa cctaataaaa gtgatgcaac caattatgct agccactctc 1150

 ctcctgtaaa cagggcctta acaccagctg ctactctaag tgctgttcag 1200

 aatttagtgg ttgaaggact gcgatgtgta gttttgccag aagatctttg 1250

 ccacaaattt ctgcaactgg cagaatctaa tacagtgaga ggaatagaaa 1300

 cctgtggaat actctgtgga aaactgacac ataatgaatt tactattacc 1350

 catgtaattg tgccaaagca gtctgcggga ccagactatt gtgacatgga 1400

 gaatgtagag gaattattca atgttcagga tcaacatgat ctcctcactc 1450

 taggatggat ccatacacat cccactcaaa ctgcattttt atccagcgtt 1500

 gatcttcaca ctcactgttc ctatcaactc atgttgccag aggccattgc 1550

 cattgtttgc tcaccaaagc ataaagacac tggcatcttc aggctcacca 1600

 atgctggcat gcttgaggtt tctgcttgta aaaaaaaggg ctttcatcca 1650

 cacaccaagg agcccaggct gttcagtata tgcaaacatg tgttggtaaa 1700

 agacataaaa ataattgtgt tggatctgag gtgatatgtt ctgaatgtaa 1750

 gcaccgtcaa catcagacac ctactcatgg acatgtggtt gccggatttt 1800

 cttaagatgt ttccagaaat gactgatatt ttatatttat acattttaga 1850

 tgacaaagct tgatatttat tgctgttgca cattttaaag ttttcttttt 1900

 gggttgctct gtgtcaagag aggttacatg gtgttaaatc ggtacctgat 1950

 aatgtaccca aatactatgg ccagataata aattgtgctg caaacaaaaa 2000

 aaaaaaaaaa 2010

<210> 4550
<211> 421
<212> PRT
<213> Homo sapien

<400> 4550
 Met Pro Asp His Thr Asp Val Ser Leu Ser Pro Glu Glu Arg Val
   1               5                  10                  15

 Arg Ala Leu Ser Lys Leu Gly Cys Asn Ile Thr Ile Ser Glu Asp
                  20                  25                  30

 Ile Thr Pro Arg Arg Tyr Phe Arg Ser Gly Val Glu Met Glu Arg
                  35                  40                  45

 Met Ala Ser Val Tyr Leu Glu Glu Gly Asn Leu Glu Asn Ala Phe
                  50                  55                  60

 Val Leu Tyr Asn Lys Phe Ile Thr Leu Phe Val Glu Lys Leu Pro
                  65                  70                  75

 Asn His Arg Asp Tyr Gln Gln Cys Ala Val Pro Glu Lys Gln Asp
                  80                  85                  90

 Ile Met Lys Lys Leu Lys Glu Ile Ala Phe Pro Arg Thr Asp Glu
                  95                 100                 105

 Leu Lys Asn Asp Leu Leu Lys Lys Tyr Asn Val Glu Tyr Gln Glu
                 110                 115                 120

 Tyr Leu Gln Ser Lys Asn Lys Tyr Lys Ala Glu Ile Leu Lys Lys
                 125                 130                 135

 Leu Glu His Gln Arg Leu Ile Glu Ala Glu Arg Lys Arg Ile Ala
                 140                 145                 150

 Gln Met Arg Gln Gln Gln Leu Glu Ser Glu Gln Phe Leu Phe Phe
                 155                 160                 165

 Glu Asp Gln Leu Lys Lys Gln Glu Leu Ala Arg Gly Gln Met Arg
                 170                 175                 180

 Ser Gln Gln Thr Ser Gly Leu Ser Glu Gln Ile Asp Gly Ser Ala
                 185                 190                 195

 Leu Ser Cys Phe Ser Thr His Gln Asn Asn Ser Leu Leu Asn Val
                 200                 205                 210

 Phe Ala Asp Gln Pro Asn Lys Ser Asp Ala Thr Asn Tyr Ala Ser
                 215                 220                 225

 His Ser Pro Pro Val Asn Arg Ala Leu Thr Pro Ala Ala Thr Leu
                 230                 235                 240

 Ser Ala Val Gln Asn Leu Val Val Glu Gly Leu Arg Cys Val Val
                 245                 250                 255

 Leu Pro Glu Asp Leu Cys His Lys Phe Leu Gln Leu Ala Glu Ser
                 260                 265                 270

 Asn Thr Val Arg Gly Ile Glu Thr Cys Gly Ile Leu Cys Gly Lys
                 275                 280                 285

 Leu Thr His Asn Glu Phe Thr Ile Thr His Val Ile Val Pro Lys
                 290                 295                 300

 Gln Ser Ala Gly Pro Asp Tyr Cys Asp Met Glu Asn Val Glu Glu
                 305                 310                 315

 Leu Phe Asn Val Gln Asp Gln His Asp Leu Leu Thr Leu Gly Trp
                 320                 325                 330

 Ile His Thr His Pro Thr Gln Thr Ala Phe Leu Ser Ser Val Asp
                 335                 340                 345

 Leu His Thr His Cys Ser Tyr Gln Leu Met Leu Pro Glu Ala Ile
                 350                 355                 360

 Ala Ile Val Cys Ser Pro Lys His Lys Asp Thr Gly Ile Phe Arg
                 365                 370                 375

 Leu Thr Asn Ala Gly Met Leu Glu Val Ser Ala Cys Lys Lys Lys
                 380                 385                 390

 Gly Phe His Pro His Thr Lys Glu Pro Arg Leu Phe Ser Ile Cys
                 395                 400                 405

 Lys His Val Leu Val Lys Asp Ile Lys Ile Ile Val Leu Asp Leu
                 410                 415                 420

 Arg


<210> 4551
<211> 4059
<212> DNA
<213> Homo sapien

<400> 4551
 gggagctggt ggcgcggcgc aggtcccggc cgagtgtggc gcagcagtgg 50

 cggcgcttcc cattcgccat gcgccggggg tgggtgcccg aaggttgcat 100

 gatggaattt gaacattact tcaagaggtt ttgtattttg gattagttaa 150

 ttgggtttgt cctctgctga ctgtttcttc ggatgcattt tttggtgtgc 200

 tcttgaggga ttaaatgcaa agagatcaca ccatggacta caaggaaagc 250

 tgcccaagtg taagcattcc cagctccgat gaacacagag agaaaaagaa 300

 gaggtttact gtttataaag ttctggtttc agtgggaaga agtgaatggt 350

 ttgtcttcag gagatatgca gagtttgata aactttataa cactttaaaa 400

 aaacagtttc ctgctatggc cctgaagatt cctgccaaga gaatatttgg 450

 tgataatttt gatccagatt ttattaaaca aagacgagca ggactaaacg 500

 aattcattca gaacctagtt aggtatccag aactttataa ccatccagat 550

 gtcagagcat tccttcaaat ggacagtcca aaacaccagt cagatccatc 600

 tgaagatgag gatgaaagaa gttctcagaa gctacactct acctcacaga 650

 acatcaacct gggaccgtct ggaaatcctc atgccaaacc aactgacttt 700

 gatttcttaa aagttattgg aaaaggcagc tttggcaagg ttcttcttgc 750

 aaaacggaaa ctggatggaa aattttatgc tgtcaaagtg ttacagaaaa 800

 aaatagttct caacagaaaa gagcaaaaac atattatggc tgaacgtaat 850

 gtgctcttga aaaatgtgaa acatccgttt ttggttggat tgcattattc 900

 cttccaaaca actgaaaagc tttattttgt tctggatttt gttaatggag 950

 gggagctttt tttccactta caaagagaac ggtcctttcc tgagcacaga 1000

 gctaggtttt acgctgctga aattgctagt gcattgggtt acttacattc 1050

 catcaaaata gtatacagag acttgaaacc agaaaatatt cttttggatt 1100

 cagtaggaca tgttgtctta acagattttg ggctttgtaa agaaggaatt 1150

 gctatttctg acaccactac cacattttgt gggacaccag agcctccttt 1200

 ttattgccga gatgttgctg aaatgtatga caatatcctt cacaaacccc 1250

 taagtttgag gccaggagtg agtcttacag cctggtccat tctggaagaa 1300

 ctcctagaaa aagacaggca aaatcgactt ggtgccaagg aagactttct 1350

 tgaaattcag aatcatcctt tttttgaatc actcagctgg gctgaccttg 1400

 tacaaaagaa gattccacca ccatttaatc ctaatgtggc tggaccagat 1450

 gatatcagaa actttgacac agcatttaca gaagaaacag ttccatattc 1500

 tgtgtgtgta tcttctgact attctatagt gaatgccagt gtattggagg 1550

 cagatgatgc attcgttggt ttctcttatg cacctccttc agaagactta 1600

 tttttgtgag cagtttgcca ttcagaaacc attgagcaaa ataagtctat 1650

 agatgggact gaaacttcta tttgtgtgaa tatattcaaa tatgtataac 1700

 tagtgcctca tttttatatg taatgatgaa aactatgaaa aaatgtattt 1750

 tcttctatgt gcaagaaaaa tagggcattt caaagagctg ttttgattaa 1800

 aatttatatt cttgtttaat aagcttattt ttaaacaatt taaaagctat 1850

 tattcttagc attaacctat ttttaaagaa accttttttg ctattgactg 1900

 ttttttccct ctaagtttac actaacatct acccaagata gactgttttt 1950

 taacagtcaa tttcagttca gctaacatat attaatacct ttgtaactct 2000

 ttgctatggc ttttgttatc acaccaaaac tatgcaattg gtacatggtt 2050

 gtttaagaag aaaccgtatt tttccatgat aaatcactgt ttgaaatatt 2100

 tggttcatgg tatgatcgaa atgtaaaagc ataattaaca cattggctgc 2150

 tagttaacaa ttggaataac tttattctgc agatcattta agaagtaaca 2200

 ggccgggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggctga 2250

 ggcgggcaga tcacctgagg tcaggagttg gagaccagcc tgaccaacat 2300

 ggacaaaccc cgtctctact aaaaatacaa aattggcagg gtgtggtggc 2350

 acatgcctat aatcccagct acttgggagg ctaaggcagg agaatcgctt 2400

 gaacccggga ggcggaggtt gcagtgagcc gagatcgcac cattgcactc 2450

 ctgcctgggc aacaagagtg aaactccatc tccaaaaaaa aaaagaaaaa 2500

 gtaacaaaag gaaattattt gtttttgaaa taccagttca actttgtgga 2550

 ttatttttcc tctgaaggaa aagaaaaggc ttaatggtta ggatttttaa 2600

 gtattcccaa agatctgaag ggtaataaaa tgtactggat tttttaaggt 2650

 ggtaccaaaa atgaatgtct gtcatatatt tatattacaa atacattata 2700

 tttatgttct attcatcttt tgaatgttta gtatgctatt aagtcattct 2750

 gaatctttgt atttgctttt gcaaataggt atttcaaagc tcttttccta 2800

 actggttaag taaaataaaa aattgagctt tctagaatat ttgcctaatt 2850

 gggaattaaa aagtaaaata ataggccagg catggtggct catgcctata 2900

 agcaccctgg gaggccgagg caggcagatt atttgagctc aggagtttga 2950

 gaccatcctg ggcaacatgg cgaaacccta tctctacaaa aaatacaaaa 3000

 attagccaga catggtggca catgccttta gtcccagcta ctctggaggc 3050

 tgaagttgga ggatggcttg agcccacgag atggaagttg cagtgaactg 3100

 aaattgtgcc actgcacttt tcagcctggg tgccacagcg agaccctagt 3150

 taagagaaaa aaaaagtaaa aacaaattgt gggtcaaagt aaatgtatac 3200

 agttttatta caatgtaaca aaagttgaaa atcaggcaga tgtgtattca 3250

 gtatccaatt caatatatct tagaaaaagc acaggaaaca gaccttaaaa 3300

 ttgtaaccta ccaactaact tacatgctta taaaagtaaa ggagaataac 3350

 tggccgggca cggtggctca tgcctataaa attccagcac tttgggaggc 3400

 caaggcagga ggatcacttg agcctatgag ttcaagacca gcctaggcaa 3450

 tgtagtgaca cctcatttct atttatttta aaaaaaagag agagtaacta 3500

 cagaagaact ttaaaaaata aaaaataagc ttaccttgga ttcttggctt 3550

 agagtagagg ttttttttaa gttatggagg aaacattttt gtaaaagttt 3600

 aatgacccac tttagatgct ccaagaacaa gcatcccttc catgtatgtc 3650

 ttgagaaaga aatcacagaa gcatttctca ccaatactct ttggcttaaa 3700

 atgttcagca gaattgggca gtgggggtga cttttcttat attaataata 3750

 tttacatcca atacactgaa tcttccttta gaggtaagac tttaatatct 3800

 atactgtaaa tatttggttt atttggcact actgtaagtt ttgtttttca 3850

 caaagctctt attatgaagc aaaataaaaa ttctagtttc ttgtatgatt 3900

 ttttgtactc attcattcct gttaagctgc caaaaattaa agtgcaatat 3950

 tgtatatttt taagaacaaa tttaaaatag aattttgatg tttctcagat 4000

 cacaagaaat acaaatctat atagtataat aaaatcagca aaaagatcaa 4050

 aaaaaaaaa 4059

<210> 4552
<211> 397
<212> PRT
<213> Homo sapien

<400> 4552
 Met Ala Leu Lys Ile Pro Ala Lys Arg Ile Phe Gly Asp Asn Phe
   1               5                  10                  15

 Asp Pro Asp Phe Ile Lys Gln Arg Arg Ala Gly Leu Asn Glu Phe
                  20                  25                  30

 Ile Gln Asn Leu Val Arg Tyr Pro Glu Leu Tyr Asn His Pro Asp
                  35                  40                  45

 Val Arg Ala Phe Leu Gln Met Asp Ser Pro Lys His Gln Ser Asp
                  50                  55                  60

 Pro Ser Glu Asp Glu Asp Glu Arg Ser Ser Gln Lys Leu His Ser
                  65                  70                  75

 Thr Ser Gln Asn Ile Asn Leu Gly Pro Ser Gly Asn Pro His Ala
                  80                  85                  90

 Lys Pro Thr Asp Phe Asp Phe Leu Lys Val Ile Gly Lys Gly Ser
                  95                 100                 105

 Phe Gly Lys Val Leu Leu Ala Lys Arg Lys Leu Asp Gly Lys Phe
                 110                 115                 120

 Tyr Ala Val Lys Val Leu Gln Lys Lys Ile Val Leu Asn Arg Lys
                 125                 130                 135

 Glu Gln Lys His Ile Met Ala Glu Arg Asn Val Leu Leu Lys Asn
                 140                 145                 150

 Val Lys His Pro Phe Leu Val Gly Leu His Tyr Ser Phe Gln Thr
                 155                 160                 165

 Thr Glu Lys Leu Tyr Phe Val Leu Asp Phe Val Asn Gly Gly Glu
                 170                 175                 180

 Leu Phe Phe His Leu Gln Arg Glu Arg Ser Phe Pro Glu His Arg
                 185                 190                 195

 Ala Arg Phe Tyr Ala Ala Glu Ile Ala Ser Ala Leu Gly Tyr Leu
                 200                 205                 210

 His Ser Ile Lys Ile Val Tyr Arg Asp Leu Lys Pro Glu Asn Ile
                 215                 220                 225

 Leu Leu Asp Ser Val Gly His Val Val Leu Thr Asp Phe Gly Leu
                 230                 235                 240

 Cys Lys Glu Gly Ile Ala Ile Ser Asp Thr Thr Thr Thr Phe Cys
                 245                 250                 255

 Gly Thr Pro Glu Pro Pro Phe Tyr Cys Arg Asp Val Ala Glu Met
                 260                 265                 270

 Tyr Asp Asn Ile Leu His Lys Pro Leu Ser Leu Arg Pro Gly Val
                 275                 280                 285

 Ser Leu Thr Ala Trp Ser Ile Leu Glu Glu Leu Leu Glu Lys Asp
                 290                 295                 300

 Arg Gln Asn Arg Leu Gly Ala Lys Glu Asp Phe Leu Glu Ile Gln
                 305                 310                 315

 Asn His Pro Phe Phe Glu Ser Leu Ser Trp Ala Asp Leu Val Gln
                 320                 325                 330

 Lys Lys Ile Pro Pro Pro Phe Asn Pro Asn Val Ala Gly Pro Asp
                 335                 340                 345

 Asp Ile Arg Asn Phe Asp Thr Ala Phe Thr Glu Glu Thr Val Pro
                 350                 355                 360

 Tyr Ser Val Cys Val Ser Ser Asp Tyr Ser Ile Val Asn Ala Ser
                 365                 370                 375

 Val Leu Glu Ala Asp Asp Ala Phe Val Gly Phe Ser Tyr Ala Pro
                 380                 385                 390

 Pro Ser Glu Asp Leu Phe Leu
                 395

<210> 4553
<211> 4359
<212> DNA
<213> Homo sapien

<400> 4553
 gctgcggctc gccgcgcggc tccagctggg gcgcggtggt cccgacggtc 50

 acccgaatcg cagggagtcg ccgctggaga ggggctcggc gcccggcggg 100

 gactgcaggc gatgacccag gatgcagcca ggggccacga catgcacgga 150

 ggaccgcatc cagcatgccc tggaacgctg cctgcatgga ctcagcctca 200

 gccgccgctc cacctcctgg tcagctgggc tgtgtctgaa ctgctggagc 250

 ctgcaggagc tggtcagcag ggacccgggc cacttcctta tcctccttga 300

 gcagatcctg cagaagaccc gagaggtcca ggagaagggc acctacgacc 350

 tgctcacccc gctggccctg ctcttctatt ccactgttct ttgtacacca 400

 cacttcccac cagactcgga tctccttctg aaggcagcca gcacctacca 450

 ccggttcctg acctggcctg ttccttactg cagcatctgc caggagctgc 500

 tcaccttcat tgatgctgaa ctcaaggccc cagggatctc ctaccagaga 550

 ctggtgaggg ctgagcaggg cctgcccatc aggagtcacc gcagctccac 600

 cgtgccaaga ccctggcaga gcttgaggac atcttcacgg agaccgcaga 650

 ggcacaggag ctggcatctg gcatcgggga tgctgcagag gcccggcggt 700

 ggctcaggac caagctgcag gcggtgggag aaaaagctgg cttccctggg 750

 gtgttagaca ctgcaaaacc agggaagctc cataccatcc ccatccctgt 800

 cgccaggtgc tacacctaca gctggagcca ggacagcttt gacatcctgc 850

 aggaaatcct gctcaaggaa caggagctgc tccagccagg gatcctggga 900

 gatgatgaag aggaggaaga ggaggaggag gaggtggagg aggacttgga 950

 aactgatggg cactgtgccg agagagattc cctgctctcc accagctctt 1000

 tggcgtccca tgactccacc ctgtcccttg catcctccca ggcctcaggg 1050

 ccggccctct cgcgccatct gctgacttcc tttgtctcag gcctctctga 1100

 tggcatggac agcggctacg tggaggacag cgaggagagc tcctccgagt 1150

 ggccttggag gcgtggcagc caggaacgcc gaggccaccg caggcctggg 1200

 cagaagttca tcaggatcta taaactcttc aagagcacca gccagctggt 1250

 actgcggagg gactctcgga gcctggaggg cagctcggac acggccctgc 1300

 ccctgaggcg ggcagggagc ctctgcagcc ccctggacga accagtatca 1350

 cccccttccc gggcccagcg ctcccgctcc ctgccccagc ccaaactcgg 1400

 tacccagctg cccagctggc ttctggcccc tgcttcacgc ccccagcgcc 1450

 gccgcccctt cctgagtgga gatgaggatc ccaaggcttc cacgctacgt 1500

 gttgtggtct ttggctccga tcggatttca gggaaggtgg ctcgggcgta 1550

 cagcaacctt cggcggctgg agaacaatcg cccactcctc acacggttct 1600

 tcaaacttca gttcttctac gtgcctgtga agcgaagtca tgggaccagc 1650

 cctggtgcct gtccaccccc tcggagccag acgccctcac ccccgacaga 1700

 ctcccctagg cacgccagcc ctggagagct gggcaccacc ccatgggagg 1750

 agagcaccaa tgacatctcc cactacctcg gcatgctgga cccctggtat 1800

 gagcgcaatg tactgggcct catgcacctg ccccctgaag tcctgtgcca 1850

 gcagtccctg aaggctgaag cccaggccct ggagggctcc ccaacccagc 1900

 tgcccatcct ggctgacatg ctactctact actgccgctt tgccgccaga 1950

 ccggtgctgc tgcaagtcta tcagaccgag ctgaccttca tcactgggga 2000

 gaagacgaca gagatcttca tccactcctt ggagctgggt cactccgctg 2050

 ccacacgtgc catcaaggcg tcaggtcctg gcagcaagcg gctgggcatc 2100

 gatggcgacc gggaggctgt tcctctaaca ctacagatta tttacagcaa 2150

 gggggccatc agtggacgaa gtcgctggag caacctggag aaggtctgta 2200

 cctccgtgaa cctcaacaag gcctgccgga agcaggagga gctggattcc 2250

 agcatggagg ccctgacgct aaacctgaca gaagtggtga aaaggcagaa 2300

 ctccaaatcc aagaagggct ttaaccagat tagcacatcg cagatcaaag 2350

 tggacaaggt gcagatcatc ggctccaaca gctgcccctt tgctgtgtgc 2400

 ctggaccagg atgagagaaa gatcctgcag agtgtagtca gatgtgaggt 2450

 ctcaccgtgc tacaagccag agaagagcga cctctcctca ccaccccaga 2500

 cgcctcctga cctgccggcc caggccgcac ctgatctctg ctcccttctc 2550

 tgcctgccca tcatgacttt cagtggagct ctgccctagt gtgggcccag 2600

 cgccagactg gacagaagcc ctggggcaac ctcctcggcc acccctccag 2650

 gacagtccct ctctgtggag aactgaatgg ccctgtgcag agccatagtc 2700

 ccactgtggg tcctgcaatg agcaggggct gggagtagag ggtttctggg 2750

 gcctcagggt tctgggaaag caacagctat cagagagaga agggccagac 2800

 cccatagcct cttagattcc tggcagtaga aggagaagga tgggtaaatt 2850

 gacctctgaa gtccctgacc attagcatgg tctaggatcc tttctagaag 2900

 gaagatctga ggctctggtg ctcaggggga tggcttgggc cttttctctc 2950

 aaccttggct gagcctaccc cttactttgc caaagacttg aggaccctgt 3000

 atgtctggag ttcagtcccc tcctctgtgg ggctcaggtg attgaaatgt 3050

 ggatgaaaca tttctctact tcaagaccac ctctccctgc aaacaccaca 3100

 cacacatggc atgcatgtac gcacatgcgc acacacacac gcacacacct 3150

 caataatttc tctcaagttt cctgagtctc cagaaaaaca gcactaacgc 3200

 tggacctgtc tactctcaga acccggcaca gattctctct tgatctcctt 3250

 ttggaatctg agattcttag aagacaggat agggttaaat ttagtagcag 3300

 ctcagttcta gctaaatcac tagaggaagt taattaactt taagccttca 3350

 tttctccagc actaaaatgg agtggagagt tggggtggaa ataagacatc 3400

 cttaaaaggt taaattgtct gcaaagcacc tagcccagtg ccgagctccc 3450

 agtaggtgtt cagtaaagct tagtgcctga ctttctgaac actgattcct 3500

 cctgtttgga gtcactggga tactctcatt gccgttggga tgttcctcac 3550

 tccttcccag ttcgtggctg aggcagaacc cagactgaag agggaagaga 3600

 cattccagag gaggattgcc ttcgtcaggg taaggggtgg gctgctcagg 3650

 ggccctaccc ttcaccccct tctgtatcag attggccctc ccactcccat 3700

 ctcactctgc gtgtacaatc ttccatatcc gcaagttcac tggcactctt 3750

 ctggcacctg ggcaagatcc cagaacagag gatggagtga ctggcctcac 3800

 agagcttagt gcccgactca ggggaaatgg gactggtgca tgggaaatgg 3850

 tcagcctagg ataggacacg agagtctgaa attcaaagca accagcttga 3900

 agtggtttga gaagctggaa gcaaacatgg gctagagaga tagggcagaa 3950

 gtcaagacga ggatctggac tgatgtggag aaagtagcca cggaagcatg 4000

 aactgtatcc tgcacaaagt ccctcttccc cgcctcctaa ttcattatgc 4050

 ccaaaaggcc ttacgtgaaa ttccagccca gagtactcat gacttgagag 4100

 acgtggacag agccagcttc taccttgcct ggccgtctct cccctgtctt 4150

 aatgtctgct cttgctctaa gctccagaag agtggcgggc catgtatctt 4200

 caatatgttt ttgctgtatg ggcaggttgt cttattatgt gatcaacaga 4250

 tgtccaggaa ctaatgagtg gaatttaata ttattgtcaa ataaaacttg 4300

 atttgtccta taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 4350

 aaaaaaaaa 4359

<210> 4554
<211> 494
<212> PRT
<213> Homo sapien

<400> 4554
 Met Asp Ser Gly Tyr Val Glu Asp Ser Glu Glu Ser Ser Ser Glu
   1               5                  10                  15

 Trp Pro Trp Arg Arg Gly Ser Gln Glu Arg Arg Gly His Arg Arg
                  20                  25                  30

 Pro Gly Gln Lys Phe Ile Arg Ile Tyr Lys Leu Phe Lys Ser Thr
                  35                  40                  45

 Ser Gln Leu Val Leu Arg Arg Asp Ser Arg Ser Leu Glu Gly Ser
                  50                  55                  60

 Ser Asp Thr Ala Leu Pro Leu Arg Arg Ala Gly Ser Leu Cys Ser
                  65                  70                  75

 Pro Leu Asp Glu Pro Val Ser Pro Pro Ser Arg Ala Gln Arg Ser
                  80                  85                  90

 Arg Ser Leu Pro Gln Pro Lys Leu Gly Thr Gln Leu Pro Ser Trp
                  95                 100                 105

 Leu Leu Ala Pro Ala Ser Arg Pro Gln Arg Arg Arg Pro Phe Leu
                 110                 115                 120

 Ser Gly Asp Glu Asp Pro Lys Ala Ser Thr Leu Arg Val Val Val
                 125                 130                 135

 Phe Gly Ser Asp Arg Ile Ser Gly Lys Val Ala Arg Ala Tyr Ser
                 140                 145                 150

 Asn Leu Arg Arg Leu Glu Asn Asn Arg Pro Leu Leu Thr Arg Phe
                 155                 160                 165

 Phe Lys Leu Gln Phe Phe Tyr Val Pro Val Lys Arg Ser His Gly
                 170                 175                 180

 Thr Ser Pro Gly Ala Cys Pro Pro Pro Arg Ser Gln Thr Pro Ser
                 185                 190                 195

 Pro Pro Thr Asp Ser Pro Arg His Ala Ser Pro Gly Glu Leu Gly
                 200                 205                 210

 Thr Thr Pro Trp Glu Glu Ser Thr Asn Asp Ile Ser His Tyr Leu
                 215                 220                 225

 Gly Met Leu Asp Pro Trp Tyr Glu Arg Asn Val Leu Gly Leu Met
                 230                 235                 240

 His Leu Pro Pro Glu Val Leu Cys Gln Gln Ser Leu Lys Ala Glu
                 245                 250                 255

 Ala Gln Ala Leu Glu Gly Ser Pro Thr Gln Leu Pro Ile Leu Ala
                 260                 265                 270

 Asp Met Leu Leu Tyr Tyr Cys Arg Phe Ala Ala Arg Pro Val Leu
                 275                 280                 285

 Leu Gln Val Tyr Gln Thr Glu Leu Thr Phe Ile Thr Gly Glu Lys
                 290                 295                 300

 Thr Thr Glu Ile Phe Ile His Ser Leu Glu Leu Gly His Ser Ala
                 305                 310                 315

 Ala Thr Arg Ala Ile Lys Ala Ser Gly Pro Gly Ser Lys Arg Leu
                 320                 325                 330

 Gly Ile Asp Gly Asp Arg Glu Ala Val Pro Leu Thr Leu Gln Ile
                 335                 340                 345

 Ile Tyr Ser Lys Gly Ala Ile Ser Gly Arg Ser Arg Trp Ser Asn
                 350                 355                 360

 Leu Glu Lys Val Cys Thr Ser Val Asn Leu Asn Lys Ala Cys Arg
                 365                 370                 375

 Lys Gln Glu Glu Leu Asp Ser Ser Met Glu Ala Leu Thr Leu Asn
                 380                 385                 390

 Leu Thr Glu Val Val Lys Arg Gln Asn Ser Lys Ser Lys Lys Gly
                 395                 400                 405

 Phe Asn Gln Ile Ser Thr Ser Gln Ile Lys Val Asp Lys Val Gln
                 410                 415                 420

 Ile Ile Gly Ser Asn Ser Cys Pro Phe Ala Val Cys Leu Asp Gln
                 425                 430                 435

 Asp Glu Arg Lys Ile Leu Gln Ser Val Val Arg Cys Glu Val Ser
                 440                 445                 450

 Pro Cys Tyr Lys Pro Glu Lys Ser Asp Leu Ser Ser Pro Pro Gln
                 455                 460                 465

 Thr Pro Pro Asp Leu Pro Ala Gln Ala Ala Pro Asp Leu Cys Ser
                 470                 475                 480

 Leu Leu Cys Leu Pro Ile Met Thr Phe Ser Gly Ala Leu Pro
                 485                 490

<210> 4555
<211> 4476
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 752-794
<223> Unknown base

<400> 4555
 agatttactt tctaaagcac tcttttcatt cccattcaaa ggactccagt 50

 ataagtgcca cataaactcg ttttctaact tttaaaactc ttcctctaaa 100

 tgcagcccaa ctcagtaaaa acgtacctaa gatctcacag tctaatgttt 150

 ccagctttta aagcctttac tcctaccctt ccctctgcct ggaaagtgtc 200

 tccattccct gctgtggaca aaatccctca aggtctttta taatttcccc 250

 caaccccaaa tcaacttgga ttttcttgga gttctcacag cattcagttt 300

 atgtcctatt cttacccttg tgttactgat attcacgaaa ttgctcagtc 350

 ctttcaagag attgcttaag gacaaagact tcttactcaa ctctgcaata 400

 ttggctacac atagctgact taataaatag tcccttgact ggtataagct 450

 gacgttacaa aaactggtaa ttccgaaacc actcatactg gacttattaa 500

 ataatccctc aactggtaca gactgacatt acaaaaacgg attaattcag 550

 agatcactga acacccaaac actcagattc ttataactat gattcagtaa 600

 atatgtgtgg aatgcctatc ttaccaggtg actatgttag gcgctgcatg 650

 agatataaga tgaaaacaag gttcccattt tccagggaag aatactggag 700

 tggaaaacgc agaggatacc acaacaggag agctatttcc gattagcggc 750

 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnntctccg 800

 tttctctgtc aaggagagat agaaaaagaa cctatttcac aggttcaaac 850

 ctacctcaag aaaaaatagt tgtggggaat gcgtcacgag acctagaaaa 900

 cggtacaaaa ccctcggggg gccgctgttt ctgacctagc gagtggcccg 950

 acccggacaa aatgcctctt cctcgaggag gcggcgacga gcccagcaac 1000

 agctcgagca cggccggccg ggccgcggga agcccgagaa cgcggcgcgc 1050

 gcagctggga ggcgaccctt acccggcgag gctcccggga ccaaacgccg 1100

 cccgacagcc acgcagaaca gacgtggcag tgcgacgcct cccccactgg 1150

 ggacacgaga cagcgacagc cacgcggtga gccggtacaa ggccctctag 1200

 gcttcagcgg gtctggatac tcggtggcat taacccttcc ctaccgccgg 1250

 ggaagacagc agtttctctg gcgaggaagt aggccgggct caggcgcctt 1300

 agccagaggg cgggcctgcg ccaccctcgg aaagcgtcac ttccacttcc 1350

 ggccggcgct ctggctctgt acctggacag ggctgcggta ggccagcggt 1400

 gggctggcgg ttgcgctcct cagattggcg gcctttcggg cggtggcttg 1450

 cgtttgagcc tcagaaagcg aggagcggcc tccacggaag ccaagctggc 1500

 cgagtgcttt taggaagaag atccttttat tgcttttgta caagaccaga 1550

 caggatctca tttgttaaac gtggtaccaa ttgggtgtct taacacagga 1600

 gcagaacttc ctagagcaga atgatgatgg tagatctgaa agtggctgcg 1650

 tacttggacc ctcagatcag ggctttgtgg gagaccaagg ggcctgcaag 1700

 agagagctcc ggtcagagta aaaaatctcc tcaaatggac tgtctcgatc 1750

 ctaagagctc ttgctggcac ttcaggaatt tcacctatga tgaagcaggt 1800

 ggaccccgtg aggctgtcag caaacttcaa gaattatgtc atctatggct 1850

 gaagccagag atccactcaa aagagcagat actggaactg ctggtgctgg 1900

 agcagttcct gactattctg cccagggaga cacagaccca gatgcagaag 1950

 caccatccac agagcattga ggaggctgtg gctctggtag aacacttgca 2000

 gagggaatct ggtcaaacat ggaatggggt tgcagtccat gagctgggaa 2050

 aggaggcagt gctcttggga gaaacagcag aggcctcaag tttcgggctg 2100

 aagccaacag agtcccaacc agtgggcgta tcccaagatg aagaattttg 2150

 gaatacatac gagggtctgc aagaacagct cagcaggaat actcataaag 2200

 agactgagcc tgtgtatgag agggctgtgc ctactcaaca gattctagct 2250

 tttcctgagc aaacaaacac caaagactgg acagtgacac ctgagcacgt 2300

 cttgcctgag tcccagagct tgttgacatt tgaagaagtg gccatgtatt 2350

 tttcccagga agaatgggag ttattggatc ccactcagaa ggccctctac 2400

 aatgatgtaa tgcaggaaaa ctatgagact gtcatctctc tagcattgtt 2450

 tgtgctcccc aaacctaaag tgatctcctg tctagagcaa ggggaagagc 2500

 catgggttca agtatccccg gagtttaagg atagtgccgg aaaatctcct 2550

 acagggttaa agctcaaaaa cgacactgaa aatcatcagc ctgtgtctct 2600

 ttctgactta gaaatacaag catcagcagg cgtcatatca aaaaaggcca 2650

 aagtaaaagt tccccagaaa acagcaggca aagaaaatca ttttgatatg 2700

 cacagagtgg gaaaatggca ccaagatttt ccagtgaaga aaagaaagaa 2750

 actttcaacc tggaaacaag agctgctcaa acttatggat cgtcacaaga 2800

 aagattgtgc aagagagaag ccttttaaat gtcaggaatg tgggaaaacc 2850

 ttcagagtta gctctgacct tattaagcac caaagaattc acactgaaga 2900

 gaaaccctat aaatgtcaac agtgtgataa gaggtttaga tggagttcag 2950

 atcttaataa gcacttaaca acacaccaag gaataaaacc atataaatgt 3000

 tcatggtgtg ggaaaagctt cggtcaaaat acaaatttac atacacacca 3050

 aagaactcat acaggagaaa agcccttcac atgtcatgaa tgtggaaaaa 3100

 aattcagtca gaactcccac cttattaaac accggagaac ccacacaggt 3150

 gagcagccat atacttgtag catatgcagg agaaacttca gcaggcggtc 3200

 aagccttctt agacaccaga aactccacct gtgaagagaa gcttgtccag 3250

 tgtcctcatt ctgaagacat tcaccaaatg gagcttggca ctaaaattta 3300

 tgtaaaagaa aaatcacaaa ccttgaaaaa ttttacatca gaaaatggga 3350

 taaacataca tttcacagaa aataatcaag acttgctctg cagccactca 3400

 gtagtcttct gtggtcacag aagtaaacat tgttggcttt gtattgatct 3450

 ctccagtcat ttttgaacac atccaataga aacattggca gcatggtctt 3500

 ccaaaacaaa aagcagtaac atgcatgttt aattgcatac cattctcttc 3550

 acagtagcag gcttaccaat ttccatagtc tcatgaggcc gaaatgaatt 3600

 acaatgtaaa gtgttccagg aaccaaattg gattttcttt cttttgtcat 3650

 tggacacggt ttgcaaagtt ggacatcact tgagttcctt cttaaacttt 3700

 tcggcaactt ctcttggatc ctgttatcac agttttttac tgtgatgaaa 3750

 tcttgttaac caccactagg gaatctccag atgaactatt aatgcactgt 3800

 cttatgcctc tcattggtga tgtttggaaa atagaagaca tctctaatgg 3850

 aatcatgggg gaaacgggtt ggaatttgta gccatggaat atatattaga 3900

 tgtaaagaat tttctgcaat aaaagaaact agacttgtta atccctgcct 3950

 tgcaatgtca gtaggataaa gcagctataa aaattagtac ttgcccaagg 4000

 cctgaaagag aattagtggg aattaagatc aacttctcag ttttgtttgt 4050

 ttacttttta attggctttt ctttgttgtt aagaatgaga gacttaattt 4100

 ccatgggagt tggagtgtgt gtgctgcagg caggatcctg tggctcattt 4150

 ggcatggaga cctggacatg tagtcagcag gagacggttc cctaaataaa 4200

 agatttgggc actggtgcta agtgttgggc gaggatgagc aaatctacat 4250

 ccatgttgtt ctgtcctgtc ctgtaagctc tacctgtctt tgttctttcc 4300

 agcacagcat ttaacagcag cctcaggtga taaatttgat ggattgccaa 4350

 aagtctgtat agcctatgga ttttcttaca acttgcttgt ttagctacag 4400

 cagtgactca ggtgcattcc ttttagagct cttaggtata tcaggaaagg 4450

 ggttaaataa ctgacctctt ccaaac 4476

<210> 4556
<211> 536
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 752-794
<223> Unknown amino acid

<400> 4556
 Met Met Val Asp Leu Lys Val Ala Ala Tyr Leu Asp Pro Gln Ile
   1               5                  10                  15

 Arg Ala Leu Trp Glu Thr Lys Gly Pro Ala Arg Glu Ser Ser Gly
                  20                  25                  30

 Gln Ser Lys Lys Ser Pro Gln Met Asp Cys Leu Asp Pro Lys Ser
                  35                  40                  45

 Ser Cys Trp His Phe Arg Asn Phe Thr Tyr Asp Glu Ala Gly Gly
                  50                  55                  60

 Pro Arg Glu Ala Val Ser Lys Leu Gln Glu Leu Cys His Leu Trp
                  65                  70                  75

 Leu Lys Pro Glu Ile His Ser Lys Glu Gln Ile Leu Glu Leu Leu
                  80                  85                  90

 Val Leu Glu Gln Phe Leu Thr Ile Leu Pro Arg Glu Thr Gln Thr
                  95                 100                 105

 Gln Met Gln Lys His His Pro Gln Ser Ile Glu Glu Ala Val Ala
                 110                 115                 120

 Leu Val Glu His Leu Gln Arg Glu Ser Gly Gln Thr Trp Asn Gly
                 125                 130                 135

 Val Ala Val His Glu Leu Gly Lys Glu Ala Val Leu Leu Gly Glu
                 140                 145                 150

 Thr Ala Glu Ala Ser Ser Phe Gly Leu Lys Pro Thr Glu Ser Gln
                 155                 160                 165

 Pro Val Gly Val Ser Gln Asp Glu Glu Phe Trp Asn Thr Tyr Glu
                 170                 175                 180

 Gly Leu Gln Glu Gln Leu Ser Arg Asn Thr His Lys Glu Thr Glu
                 185                 190                 195

 Pro Val Tyr Glu Arg Ala Val Pro Thr Gln Gln Ile Leu Ala Phe
                 200                 205                 210

 Pro Glu Gln Thr Asn Thr Lys Asp Trp Thr Val Thr Pro Glu His
                 215                 220                 225

 Val Leu Pro Glu Ser Gln Ser Leu Leu Thr Phe Glu Glu Val Ala
                 230                 235                 240

 Met Tyr Phe Ser Gln Glu Glu Trp Glu Leu Leu Asp Pro Thr Gln
                 245                 250                 255

 Lys Ala Leu Tyr Asn Asp Val Met Gln Glu Asn Tyr Glu Thr Val
                 260                 265                 270

 Ile Ser Leu Ala Leu Phe Val Leu Pro Lys Pro Lys Val Ile Ser
                 275                 280                 285

 Cys Leu Glu Gln Gly Glu Glu Pro Trp Val Gln Val Ser Pro Glu
                 290                 295                 300

 Phe Lys Asp Ser Ala Gly Lys Ser Pro Thr Gly Leu Lys Leu Lys
                 305                 310                 315

 Asn Asp Thr Glu Asn His Gln Pro Val Ser Leu Ser Asp Leu Glu
                 320                 325                 330

 Ile Gln Ala Ser Ala Gly Val Ile Ser Lys Lys Ala Lys Val Lys
                 335                 340                 345

 Val Pro Gln Lys Thr Ala Gly Lys Glu Asn His Phe Asp Met His
                 350                 355                 360

 Arg Val Gly Lys Trp His Gln Asp Phe Pro Val Lys Lys Arg Lys
                 365                 370                 375

 Lys Leu Ser Thr Trp Lys Gln Glu Leu Leu Lys Leu Met Asp Arg
                 380                 385                 390

 His Lys Lys Asp Cys Ala Arg Glu Lys Pro Phe Lys Cys Gln Glu
                 395                 400                 405

 Cys Gly Lys Thr Phe Arg Val Ser Ser Asp Leu Ile Lys His Gln
                 410                 415                 420

 Arg Ile His Thr Glu Glu Lys Pro Tyr Lys Cys Gln Gln Cys Asp
                 425                 430                 435

 Lys Arg Phe Arg Trp Ser Ser Asp Leu Asn Lys His Leu Thr Thr
                 440                 445                 450

 His Gln Gly Ile Lys Pro Tyr Lys Cys Ser Trp Cys Gly Lys Ser
                 455                 460                 465

 Phe Gly Gln Asn Thr Asn Leu His Thr His Gln Arg Thr His Thr
                 470                 475                 480

 Gly Glu Lys Pro Phe Thr Cys His Glu Cys Gly Lys Lys Phe Ser
                 485                 490                 495

 Gln Asn Ser His Leu Ile Lys His Arg Arg Thr His Thr Gly Glu
                 500                 505                 510

 Gln Pro Tyr Thr Cys Ser Ile Cys Arg Arg Asn Phe Ser Arg Arg
                 515                 520                 525

 Ser Ser Leu Leu Arg His Gln Lys Leu His Leu
                 530                 535

<210> 4557
<211> 1428
<212> DNA
<213> Homo sapien

<400> 4557
 aaacgtggcc gggtctgcaa gctaggtgcc agcggggaaa gtttccctgc 50

 ttcttatcgt ctgctttaac gccttaaata gcccgctgaa ggctgcagca 100

 ggtgctaggt agcagcctcc cggccctcgg gaaaggcggg gtggggaggc 150

 gagagcagct tagcctcctc gacctccctt cctggtgacg gacgaacagt 200

 tcccgtagaa tttcgcttca ccgagtgacc ttgagcccag ggcgacggtc 250

 agcttgttaa ttcctggctg caggaacttt gtgagaattt taatgcatgg 300

 aaaagctgtc catgttccaa ctgctgtaca tccaaaagtc tcagtgtaat 350

 agcaggacca aaatattctg tcaatcagct gaccatatac ttaatgactc 400

 ctaaaatctc gtggacttct aagaaagcgc catggcctgt gctgctgtta 450

 tgattcctgg gttgttgcgg tgctctgttg gagccatccg tattgaggct 500

 gcgtcactga gattgacact cagcactttg cgccacctta ctctaaccag 550

 cataatgaaa tccaaaagga aaactgatca catggagaga actgcaagtg 600

 tccttcgacg ggagattgtg tcagcagcta aggtgtgtgg agctgccagt 650

 gagtcaccgt cagtgaagag cctccgcttg cttgttgctg atcaagactt 700

 ttcctttaaa gctggccagt gggttgattt ctttattcca ggagtctctg 750

 tggttggtgg gttttcaata tgctccagtc ccagactgct agaacaagag 800

 agagtgatag aattggcagt gaaatatacg aaccaccctc ctgccctctg 850

 ggttcacaat acgtgtacac ttgactgtga agtggctgtg agagtgggtg 900

 gagagttctt ctttgaccct cagcctgcgg atgcctctag aaacctcgtg 950

 ttgattgcag gaggagtcgg aattaaccct ctgctttcca tcctgcggca 1000

 cgcagcagat ctcctcagag agcaggcaaa caaaagaaat ggatatgaga 1050

 taggaacaat aaaactattc tacagtgcaa aaaataccag cgaactcctg 1100

 tttaagaaaa atatccttga tttagtaaat gaatttcctg agaagattgc 1150

 atgcagtttg catgttacaa aacagactac acaaatcaat gcggaactca 1200

 agccatacat cacggaagga agaataacgg agaaggagat aagagatcat 1250

 atttcaaaag agactttgtt ctatatttgt ggcccacctc caatgacaga 1300

 ctttttctcc aagcaactgg aaaacaacca tgtacccaaa gaacacattt 1350

 gctttgagaa gtggtggtag gaggcagaca aaggcagaaa aaataaagag 1400

 gtgagatcta aaaaaaaaaa aaaaaaaa 1428

<210> 4558
<211> 312
<212> PRT
<213> Homo sapien

<400> 4558
 Met Ala Cys Ala Ala Val Met Ile Pro Gly Leu Leu Arg Cys Ser
   1               5                  10                  15

 Val Gly Ala Ile Arg Ile Glu Ala Ala Ser Leu Arg Leu Thr Leu
                  20                  25                  30

 Ser Thr Leu Arg His Leu Thr Leu Thr Ser Ile Met Lys Ser Lys
                  35                  40                  45

 Arg Lys Thr Asp His Met Glu Arg Thr Ala Ser Val Leu Arg Arg
                  50                  55                  60

 Glu Ile Val Ser Ala Ala Lys Val Cys Gly Ala Ala Ser Glu Ser
                  65                  70                  75

 Pro Ser Val Lys Ser Leu Arg Leu Leu Val Ala Asp Gln Asp Phe
                  80                  85                  90

 Ser Phe Lys Ala Gly Gln Trp Val Asp Phe Phe Ile Pro Gly Val
                  95                 100                 105

 Ser Val Val Gly Gly Phe Ser Ile Cys Ser Ser Pro Arg Leu Leu
                 110                 115                 120

 Glu Gln Glu Arg Val Ile Glu Leu Ala Val Lys Tyr Thr Asn His
                 125                 130                 135

 Pro Pro Ala Leu Trp Val His Asn Thr Cys Thr Leu Asp Cys Glu
                 140                 145                 150

 Val Ala Val Arg Val Gly Gly Glu Phe Phe Phe Asp Pro Gln Pro
                 155                 160                 165

 Ala Asp Ala Ser Arg Asn Leu Val Leu Ile Ala Gly Gly Val Gly
                 170                 175                 180

 Ile Asn Pro Leu Leu Ser Ile Leu Arg His Ala Ala Asp Leu Leu
                 185                 190                 195

 Arg Glu Gln Ala Asn Lys Arg Asn Gly Tyr Glu Ile Gly Thr Ile
                 200                 205                 210

 Lys Leu Phe Tyr Ser Ala Lys Asn Thr Ser Glu Leu Leu Phe Lys
                 215                 220                 225

 Lys Asn Ile Leu Asp Leu Val Asn Glu Phe Pro Glu Lys Ile Ala
                 230                 235                 240

 Cys Ser Leu His Val Thr Lys Gln Thr Thr Gln Ile Asn Ala Glu
                 245                 250                 255

 Leu Lys Pro Tyr Ile Thr Glu Gly Arg Ile Thr Glu Lys Glu Ile
                 260                 265                 270

 Arg Asp His Ile Ser Lys Glu Thr Leu Phe Tyr Ile Cys Gly Pro
                 275                 280                 285

 Pro Pro Met Thr Asp Phe Phe Ser Lys Gln Leu Glu Asn Asn His
                 290                 295                 300

 Val Pro Lys Glu His Ile Cys Phe Glu Lys Trp Trp
                 305                 310

<210> 4559
<211> 3088
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2955, 2974, 2984-2985, 2991
<223> Unknown base

<400> 4559
 tggggagggg tctcgctcag tcccgggagc ttttcccggt ttcccctccc 50

 cttcccgggt cattcccggc agggaggtga cgaggtaggg gcagagcgga 100

 tggaagccgg agatctcagg ttcccggaat actccggctg gggccttcgg 150

 gcttctcctg tcccctccct acccccgtgc ctcgggtttc tccctccgtc 200

 cacaccgccc ggggctactg gactgagcgg cgcccaggca gtcccggggg 250

 cccttctcct gctccccacc cggccacact cctggagacc taacttccgc 300

 gcgcgagttt cccacgctgc gcccttgcag tgcgcgcctg ggaaggggct 350

 gcccggggcc accctgccgg caggggcggg agccgtgcgg gctccgtgag 400

 gcgcctggat cggagcgcgg gcccaggaga gggcccccgg ggcagtgggt 450

 gccccagtcg ctcggcgaag gcaggggagc cggggcgggc cgggcgcgct 500

 ggagggttcc gggcactcaa cgcgctcgcg ccttcctctc cgcagccccc 550

 cgggatgcgg tagcggccgc tgtgcggagg ccgcgaagca gctgcagccg 600

 ccgccgcgca gatccacgct ggctccgtgc gccatggtca cccacagcaa 650

 gtttcccgcc gccgggatga gccgccccct ggacaccagc ctgcgcctca 700

 agaccttcag ctccaagagc gagtaccagc tggtggtgaa cgcagtgcgc 750

 aagctgcagg agagcggctt ctactggagc gcagtgaccg gcggcgaggc 800

 gaacctgctg ctcagtgccg agcccgccgg cacctttctg atccgcgaca 850

 gctcggacca gcgccacttc ttcacgctca gcgtcaagac ccagtctggg 900

 accaagaacc tgcgcatcca gtgtgagggg ggcagcttct ctctgcagag 950

 cgatccccgg agcacgcagc ccgtgccccg cttcgactgc gtgctcaagc 1000

 tggtgcacca ctacatgccg ccccctggag ccccctcctt cccctcgcca 1050

 cctactgaac cctcctccga ggtgcccgag cagccgtctg cccagccact 1100

 ccctgggagt ccccccagaa gagcctatta catctactcc gggggcgaga 1150

 agatccccct ggtgttgagc cggcccctct cctccaacgt ggccactctt 1200

 cagcatctct gtcggaagac cgtcaacggc cacctggact cctatgagaa 1250

 agtcacccag ctgccggggc ccattcggga gttcctggac cagtacgatg 1300

 ccccgcttta aggggtaaag ggcgcaaagg gcatgggtcg ggagagggga 1350

 cgcaggcccc tctcctccgt ggcacatggc acaagcacaa gaagccaacc 1400

 aggagagagt cctgtagctc tggggggaaa gagggcggac aggcccctcc 1450

 ctctgccctc tccctgcaga atgtggcagg cggacctgga atgtgttgga 1500

 gggaaggggg agtaccacct gagtctccag cttctccgga ggagccagct 1550

 gtcctggtgg gacgatagca accacaagtg gattctcctt caattcctca 1600

 gcttcccctc tgcctccaaa caggggacac ttcgggaatg ctgaactaat 1650

 gagaactgcc agggaatctt caaactttcc aacggaactt gtttgctctt 1700

 tgatttggtt taaacctgag ctggttgtgg agcctgggaa aggtggaaga 1750

 gagagaggtc ctgagggccc cagggctgcg ggctggcgaa ggaaatggtc 1800

 acaccccccg cccaccccag gcgaggatcc tggtgacatg ctcctctccc 1850

 tggctccggg gagaagggct tggggtgacc tgaagggaac catcctggtg 1900

 ccccacatcc tctcctccgg gacagtcacc gaaaacacag gttccaaagt 1950

 ctacctggtg cctgagagcc cagggccctt cctccgtttt aagggggaag 2000

 caacatttgg aggggacgga tgggctggtc agctggtctc cttttcctac 2050

 tcatactata ccttcctgta cctgggtgga tggagcggga ggatggagga 2100

 gacgggacat ctttcacctc aggctcctgg tagagaagac aggggattct 2150

 actctgtgcc tcctgactat gtctggctaa gagattcgcc ttaaatgctc 2200

 cctgtcccat ggagagggac ccagcatagg aaagccacat actcagcctg 2250

 gatgggtgga gaggctgagg gactcactgg agggcaccaa gccagcccac 2300

 agccagggaa gtggggaggg ggggcggaaa cccatgcctc ccagctgagc 2350

 actgggaatg tcagcccagt aagtattggc cagtcaggcg cctcgtggtc 2400

 agagcagagc caccaggtcc cactgccccg agccctgcac agccctccct 2450

 cctgcctggg tgggggaggc tggaggtcat tggagaggct ggactgctgc 2500

 caccccgggt gctcccgctc tgccatagca ctgatcagtg acaatttaca 2550

 ggaatgtagc agcgatggaa ttacctggaa cagttttttg tttttgtttt 2600

 tgtttttgtt tttgtggggg ggggcaacta aacaaacaca aagtattctg 2650

 tgtcaggtat tgggctggac agggcagttg tgtgttgggg tggttttttt 2700

 ctctattttt ttgtttgttt cttgtttttt aataatgttt acaatctgcc 2750

 tcaatcactc tgtcttttat aaagattcca cctccagtcc tctctcctcc 2800

 cccctactca ggcccttgag gctattagga gatgcttgaa gaactcaaca 2850

 aaatcccaat ccaagtcaaa ctttgcacat atttatattt atattcagaa 2900

 aagaaacatt tcagtaattt ataataaaga gcactatttt ttaatgaaaa 2950

 aaaanaaaaa aaaaatgaat tcangaatga aaannatgag nggatgaatg 3000

 aatggtaatg gataatgggc tatgaagtca tatttaaagg cactatctca 3050

 tttaaaaaca atctaaataa ataactacaa tgataaaa 3088

<210> 4560
<211> 132
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2955, 2974, 2984-2985, 2991
<223> Unknown amino acid

<400> 4560
 Trp Gly Gly Val Ser Leu Ser Pro Gly Ser Phe Ser Arg Phe Pro
   1               5                  10                  15

 Leu Pro Phe Pro Gly His Ser Arg Gln Gly Gly Asp Glu Val Gly
                  20                  25                  30

 Ala Glu Arg Met Glu Ala Gly Asp Leu Arg Phe Pro Glu Tyr Ser
                  35                  40                  45

 Gly Trp Gly Leu Arg Ala Ser Pro Val Pro Ser Leu Pro Pro Cys
                  50                  55                  60

 Leu Gly Phe Leu Pro Pro Ser Thr Pro Pro Gly Ala Thr Gly Leu
                  65                  70                  75

 Ser Gly Ala Gln Ala Val Pro Gly Ala Leu Leu Leu Leu Pro Thr
                  80                  85                  90

 Arg Pro His Ser Trp Arg Pro Asn Phe Arg Ala Arg Val Ser His
                  95                 100                 105

 Ala Ala Pro Leu Gln Cys Ala Pro Gly Lys Gly Leu Pro Gly Ala
                 110                 115                 120

 Thr Leu Pro Ala Gly Ala Gly Ala Val Arg Ala Pro
                 125                 130

<210> 4561
<211> 2485
<212> DNA
<213> Homo sapien

<400> 4561
 aaaaaaaaaa aaaaaaccgg ctcgcggcgc gtggaggctg ctcccagccg 50

 cgcgcgagtc agactcgggt gggggtcccg gcggcggtag cggcggcggc 100

 ggtgcgagca tgtcgtggct cttcggcatt aacaagggcc ccaagggtga 150

 aggcgcgggg ccgccgccgc ctttgccgcc cgcgcagccc ggggccgagg 200

 gcggcgggga ccgcggcttg ggagaccggc cggcgcccaa ggacaaatgg 250

 agcaacttcg accccaccgg cctggagcgc gccgccaagg cggcgcgcga 300

 gctggagcac tcgcgttatg ccaaggacgc cctgaatctg gcacagatgc 350

 aggagcagac gctgcagttg gagcaacagt ccaagctcaa agagtatgag 400

 gccgccgtgg agcagctcaa gagcgagcag atccgggcgc aggctgagga 450

 gaggaggaag accctgagcg aggagacccg gcagcaccag gccagggccc 500

 agtatcaaga caagctggcc cggcagcgct acgaggacca actgaagcag 550

 cagcaacttc tcaatgagga gaatttacgg aagcaggagg agtccgtgca 600

 gaagcaggaa gccatgcggc gagccaccgt ggagcgggag atggagctgc 650

 ggcacaagaa tgagatgctg cgagtggagg ccgaggcccg ggcgcgcgcc 700

 aaggccgagc gggagaatgc agacatcatc cgcgagcaga tccgcctgaa 750

 ggcggccgag caccgtcaga ccgtcttgga gtccatcagg acggctggca 800

 ccttgtttgg ggaaggattc cgtgcctttg tgacagactg ggacaaagtg 850

 acagccacgg tggctgggct gacgctgctg gctgttgggg tctactcagc 900

 caagaatgcc acgcttgtcg ccggccgctt catcgaggct cggctgggga 950

 agccgtccct agtgagggag acgtcccgca tcacggtgct tgaggcgctg 1000

 cggcacccca tccaggtcag ccggcggctc ctcagtcgac cccaggacgc 1050

 gctggagggt gttgtgctca gtcccagcct ggaagcacgg gtgcgcgaca 1100

 tcgccatagc aacaaggaac accaagaaga accgcagcct gtacaggaac 1150

 atcctgatgt acgggccacc aggcaccggg aagacgctgt ttgccaagaa 1200

 actcgccctg cactcaggca tggactacgc catcatgaca ggcggggacg 1250

 tggcccccat ggggcgggaa ggcgtgaccg ccatgcacaa gctctttgac 1300

 tgggccaata ccagccggcg cggcctcctg ctctttgtgg atgaagcgga 1350

 cgccttcctt cggaagcgag ccaccgagaa gataagcgag gacctcaggg 1400

 ccacactgaa cgccttcctg taccgcacgg gccagcacag caacaagttc 1450

 atgctggtcc tggccagcaa ccaaccagag cagttcgact gggccatcaa 1500

 tgaccgcatc aatgagatgg tccacttcga cctgccaggg caggaggaac 1550

 gggagcgcct ggtgagaatg tattttgaca agtatgttct taagccggcc 1600

 acagaaggaa agcagcgcct gaagctggcc cagtttgact acgggaggaa 1650

 gtgctcggag gtcgctcggc tgacggaggg catgtcgggc cgggagatcg 1700

 ctcagctggc cgtgtcctgg caggccacgg cgtatgcctc cgaggacggg 1750

 gtcctgaccg aggccatgat ggacacccgc gtgcaagatg ctgtccagca 1800

 gcaccagcag aagatgtgct ggctgaaggc ggaagggcct gggcgtgggg 1850

 acgagccttc cccatcctga gtccacaggg agatccacag ctcacggagc 1900

 ctggccgcgg acccctccca cccctgcctt gccggcccct gcacatttag 1950

 gatatgctcc tgggtgggga ctgggctgtg cccagggcct ctgtccccca 2000

 ggatgtcttg tggtgcgggt cggccgttct gccccccagg gcaccccctg 2050

 ttgtaggcac tggctaggga ggggcaggcc tccttcctgc ccctcgagac 2100

 actcttggga gatgcatttt ccgtctggct cacaggggga gggtgaggct 2150

 ttgcacccca gcccctgccc aggccactgt gagggtgggt gctggctgac 2200

 cccccggggc agcaggagcc aggcaggtga tgtctttgtt ctcggctccc 2250

 acagcagagc caggtgaggg ggcgcctgcc agggccagac ccaggtgggg 2300

 cagcctgaac cctgcttccc cctgtggccg gcatgccccg atctttcaca 2350

 cactggtgac cctgagagag gagggaggag ggaacctggc gggggtgtct 2400

 gaggccgcac tgtcagctgg ccggtccaag cctgtggctg gagctggggt 2450

 ctgtttacct aataaagtcc cacaggtgcc tcatt 2485

<210> 4562
<211> 586
<212> PRT
<213> Homo sapien

<400> 4562
 Met Ser Trp Leu Phe Gly Ile Asn Lys Gly Pro Lys Gly Glu Gly
   1               5                  10                  15

 Ala Gly Pro Pro Pro Pro Leu Pro Pro Ala Gln Pro Gly Ala Glu
                  20                  25                  30

 Gly Gly Gly Asp Arg Gly Leu Gly Asp Arg Pro Ala Pro Lys Asp
                  35                  40                  45

 Lys Trp Ser Asn Phe Asp Pro Thr Gly Leu Glu Arg Ala Ala Lys
                  50                  55                  60

 Ala Ala Arg Glu Leu Glu His Ser Arg Tyr Ala Lys Asp Ala Leu
                  65                  70                  75

 Asn Leu Ala Gln Met Gln Glu Gln Thr Leu Gln Leu Glu Gln Gln
                  80                  85                  90

 Ser Lys Leu Lys Glu Tyr Glu Ala Ala Val Glu Gln Leu Lys Ser
                  95                 100                 105

 Glu Gln Ile Arg Ala Gln Ala Glu Glu Arg Arg Lys Thr Leu Ser
                 110                 115                 120

 Glu Glu Thr Arg Gln His Gln Ala Arg Ala Gln Tyr Gln Asp Lys
                 125                 130                 135

 Leu Ala Arg Gln Arg Tyr Glu Asp Gln Leu Lys Gln Gln Gln Leu
                 140                 145                 150

 Leu Asn Glu Glu Asn Leu Arg Lys Gln Glu Glu Ser Val Gln Lys
                 155                 160                 165

 Gln Glu Ala Met Arg Arg Ala Thr Val Glu Arg Glu Met Glu Leu
                 170                 175                 180

 Arg His Lys Asn Glu Met Leu Arg Val Glu Ala Glu Ala Arg Ala
                 185                 190                 195

 Arg Ala Lys Ala Glu Arg Glu Asn Ala Asp Ile Ile Arg Glu Gln
                 200                 205                 210

 Ile Arg Leu Lys Ala Ala Glu His Arg Gln Thr Val Leu Glu Ser
                 215                 220                 225

 Ile Arg Thr Ala Gly Thr Leu Phe Gly Glu Gly Phe Arg Ala Phe
                 230                 235                 240

 Val Thr Asp Trp Asp Lys Val Thr Ala Thr Val Ala Gly Leu Thr
                 245                 250                 255

 Leu Leu Ala Val Gly Val Tyr Ser Ala Lys Asn Ala Thr Leu Val
                 260                 265                 270

 Ala Gly Arg Phe Ile Glu Ala Arg Leu Gly Lys Pro Ser Leu Val
                 275                 280                 285

 Arg Glu Thr Ser Arg Ile Thr Val Leu Glu Ala Leu Arg His Pro
                 290                 295                 300

 Ile Gln Val Ser Arg Arg Leu Leu Ser Arg Pro Gln Asp Ala Leu
                 305                 310                 315

 Glu Gly Val Val Leu Ser Pro Ser Leu Glu Ala Arg Val Arg Asp
                 320                 325                 330

 Ile Ala Ile Ala Thr Arg Asn Thr Lys Lys Asn Arg Ser Leu Tyr
                 335                 340                 345

 Arg Asn Ile Leu Met Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu
                 350                 355                 360

 Phe Ala Lys Lys Leu Ala Leu His Ser Gly Met Asp Tyr Ala Ile
                 365                 370                 375

 Met Thr Gly Gly Asp Val Ala Pro Met Gly Arg Glu Gly Val Thr
                 380                 385                 390

 Ala Met His Lys Leu Phe Asp Trp Ala Asn Thr Ser Arg Arg Gly
                 395                 400                 405

 Leu Leu Leu Phe Val Asp Glu Ala Asp Ala Phe Leu Arg Lys Arg
                 410                 415                 420

 Ala Thr Glu Lys Ile Ser Glu Asp Leu Arg Ala Thr Leu Asn Ala
                 425                 430                 435

 Phe Leu Tyr Arg Thr Gly Gln His Ser Asn Lys Phe Met Leu Val
                 440                 445                 450

 Leu Ala Ser Asn Gln Pro Glu Gln Phe Asp Trp Ala Ile Asn Asp
                 455                 460                 465

 Arg Ile Asn Glu Met Val His Phe Asp Leu Pro Gly Gln Glu Glu
                 470                 475                 480

 Arg Glu Arg Leu Val Arg Met Tyr Phe Asp Lys Tyr Val Leu Lys
                 485                 490                 495

 Pro Ala Thr Glu Gly Lys Gln Arg Leu Lys Leu Ala Gln Phe Asp
                 500                 505                 510

 Tyr Gly Arg Lys Cys Ser Glu Val Ala Arg Leu Thr Glu Gly Met
                 515                 520                 525

 Ser Gly Arg Glu Ile Ala Gln Leu Ala Val Ser Trp Gln Ala Thr
                 530                 535                 540

 Ala Tyr Ala Ser Glu Asp Gly Val Leu Thr Glu Ala Met Met Asp
                 545                 550                 555

 Thr Arg Val Gln Asp Ala Val Gln Gln His Gln Gln Lys Met Cys
                 560                 565                 570

 Trp Leu Lys Ala Glu Gly Pro Gly Arg Gly Asp Glu Pro Ser Pro
                 575                 580                 585

 Ser


<210> 4563
<211> 3490
<212> DNA
<213> Homo sapien

<400> 4563
 ccacgcgtcc gtaaaagcca aaatgggaaa ggaaaagact catatcaaca 50

 ttgtcgtcat tggacacgta gattcgggca agtccaccac tactggccat 100

 ctgatctata aatgcggtgg catcgacaaa agaaccattg aaaaatttga 150

 gaaggaggct gctgagatgg gaaagggctc cttcaagtat gcctgggtct 200

 tggataaact gaaagctgag cgtgaacgtg gtatcaccat tgatatctcc 250

 ttgtggaaat ttgagaccag caagtactat gtgactatca ttgatgcccc 300

 aggacacaga gactttatca aaaacatgat tacagggaca tctcaggctg 350

 actgtgctgt cctgattgtt gctgctggtg ttggtgaatt tgaagctggt 400

 atctccaaga atgggcagac ccgagagcat gcccttctgg cttacacact 450

 gggtgtgaaa caactaattg tcggtgttaa caaaatggat tccactgagc 500

 caccctacag ccagaagaga tatgaggaaa ttgttaagga agtcagcact 550

 tacattaaga aaattggcta caaccccgac acagtagcat ttgtgccaat 600

 ttctggttgg aatggtgaca acatgctgga gccaagtgct aacatgcctt 650

 ggttcaaggg atggaaagtc acccgtaagg atggcaatgc cagtggaacc 700

 acgctgcttg aggctctgga ctgcatccta ccaccaactc gtccaactga 750

 caagcccttg cgcctgcctc tccaggatgt ctacaaaatt ggtggtattg 800

 gtactgttcc tgttggccga gtggagactg gtgttctcaa acccggtatg 850

 gtggtcacct ttgctccagt caacgttaca acggaaagta aaatctgtcg 900

 aaatgcacca tgaagctttg agtgaagctc ttcctgggga caatgtgggc 950

 ttcaatgtca agaatgtgtc tgtcaaggat gttcgtcgtg gcaacgttgc 1000

 tggtgacagc aaaaatgacc caccaatgga agcagctggc ttcactgctc 1050

 aggtgattat cctgaaccat ccaggccaaa taagcgccgg ctatgcccct 1100

 gtattggatt gccacacggc tcacattgca tgcaagtttg ctgagctgaa 1150

 ggaaaagatt gatcgccgtt ctggtaaaaa gctggaagat ggccctaaat 1200

 tcttgaagtc tggtgatgct gccattgttg atatggttcc tggcaagccc 1250

 atgtgtgttg agagcttctc agactatcca cctttgggtc gctttgctgt 1300

 tcgtgatatg agacagacag ttgcggtggg tgtcatcaaa gcagtggaca 1350

 agaaggctgc tggagctggc aaggtcacca agtctgccca gaaagctcag 1400

 aaggctaaat gaatattatc cctaatacct gccaccccac tcttaatcag 1450

 tggtggaaga acggtctcag aactgtttgt ttcaattggc catttaagtt 1500

 tagtagtaaa agactggtta atgataacaa tgcatcgtaa aaccttcaga 1550

 aggaaaggag aatgttttgt ggaccacttt ggttttcttt tttgcgtgtg 1600

 gcagttttaa gttattagtt tttaaaatca gtacttttta atggaaacaa 1650

 cttgaccaaa aatttgtcac agaattttga gacccattaa aaaagttaaa 1700

 tgagaaacct gtgtgttcct ttggtcaaca ccgagacatt taggtgaaag 1750

 acatctaatt ctggttttac gaatctggaa acttcttgaa aatgtaattc 1800

 ttgagttaac acttctgggt ggagaatagg gttgttttcc ccccacataa 1850

 ttggaagggg aaggaatatc atttaaagct atgggagggt tgctttgatt 1900

 acaacactgg agagaaatgc agcatgttgc tgattgcctg tcactaaaac 1950

 aggccaaaaa ctgagtcctt gtgttgcata gaaagcttca tgttgctaaa 2000

 ccaatgttaa gtgaatcttt ggaaacaaaa tgtttccaaa ttactgggat 2050

 gtgcatgttg aaacgtgggt taaaatgact gggcagtgaa agttgactat 2100

 ttgccatgac ataagaaata agtgtagtgg ctagtgtaca ccctatgagt 2150

 ggaagggtcc attttgaagt cagtggagta agctttatgc cagtttgatg 2200

 gtttcacaag ttctattgag tgctattcag aataggaaca aggttctaat 2250

 agaaaaagat ggcaatttga agtagctata aaattagact aatctacatt 2300

 gcttttctcc tgcagagtct aatacctttt atgctttgat aattagcagt 2350

 ttgtctactt ggtcactagg aatgaaacta catggtaata ggcttaacag 2400

 gtgtaatagc ccacttactc ctgaatcttt aagcatttgt gcatttgaaa 2450

 aatgcttttc gcgatcttcc tgctgggatt acaggcatga gccactgtgc 2500

 ctgacctccc atatgtaaaa gtgtctaaag gttttttttt ggttataaaa 2550

 ggaaaatttt tgcttaagtt tgaaggatag gtaaaattaa aagacatgct 2600

 ttctgtttgt gtgatggttt ttaaaaattt tttttaagat ggagttcttg 2650

 ttgcccaggc tagaatgcaa tggcaaaatc tcactgcaat ctcctcctcc 2700

 tgggttcaag caattctcct acttcagcct cccaagtagc tgggattaca 2750

 ggcatgtgct aatttggtgt ttttaataga gatgaggttt ttccatgttg 2800

 gtcaggctgg tctcaaactc ctgaccttag gtgatcgcct cggcctccta 2850

 aagtgctgga attacaggca tgagccacca tgcctggcca ggacatgtgt 2900

 tcttaaggac atgctaagca ggagttaaag cagcccaaga gataaggcct 2950

 cttaaagtga ctggcaatgt gtattgctca agattcaaag gtacttgaat 3000

 tggccataga caagtctgta atgaagtgtt atcgttttcc ctcatctgag 3050

 tctgaattag ataaaatgcc ttcccatcag ccagtgctct gaggtatcaa 3100

 gtctaaattg aactagagat ttttgtcctt agtttctttg ctatctaatg 3150

 tttacacaag taaatagtct aagatttgct ggatgacaga aaaaacaggt 3200

 aaggccttta atagatggcc aatagatgcc ctgataatga aagttgacac 3250

 ctgtaagatt taccagtaga gaattcttga catgcaagga agcaagattt 3300

 aactgaaaaa ttgttcccac tggaagcagg aatgagtcag tttacttgca 3350

 tatactgaga ttgagattaa cttcctgtga aacccagtgt cttagacaac 3400

 tgtggcttga gcaccacctg ctggtattca ttacaaactt gctcactaca 3450

 ataaatgaat tttaagcttt aaaaaaaaaa aaaaaaaagg 3490

<210> 4564
<211> 303
<212> PRT
<213> Homo sapien

<400> 4564
 His Ala Ser Val Lys Ala Lys Met Gly Lys Glu Lys Thr His Ile
   1               5                  10                  15

 Asn Ile Val Val Ile Gly His Val Asp Ser Gly Lys Ser Thr Thr
                  20                  25                  30

 Thr Gly His Leu Ile Tyr Lys Cys Gly Gly Ile Asp Lys Arg Thr
                  35                  40                  45

 Ile Glu Lys Phe Glu Lys Glu Ala Ala Glu Met Gly Lys Gly Ser
                  50                  55                  60

 Phe Lys Tyr Ala Trp Val Leu Asp Lys Leu Lys Ala Glu Arg Glu
                  65                  70                  75

 Arg Gly Ile Thr Ile Asp Ile Ser Leu Trp Lys Phe Glu Thr Ser
                  80                  85                  90

 Lys Tyr Tyr Val Thr Ile Ile Asp Ala Pro Gly His Arg Asp Phe
                  95                 100                 105

 Ile Lys Asn Met Ile Thr Gly Thr Ser Gln Ala Asp Cys Ala Val
                 110                 115                 120

 Leu Ile Val Ala Ala Gly Val Gly Glu Phe Glu Ala Gly Ile Ser
                 125                 130                 135

 Lys Asn Gly Gln Thr Arg Glu His Ala Leu Leu Ala Tyr Thr Leu
                 140                 145                 150

 Gly Val Lys Gln Leu Ile Val Gly Val Asn Lys Met Asp Ser Thr
                 155                 160                 165

 Glu Pro Pro Tyr Ser Gln Lys Arg Tyr Glu Glu Ile Val Lys Glu
                 170                 175                 180

 Val Ser Thr Tyr Ile Lys Lys Ile Gly Tyr Asn Pro Asp Thr Val
                 185                 190                 195

 Ala Phe Val Pro Ile Ser Gly Trp Asn Gly Asp Asn Met Leu Glu
                 200                 205                 210

 Pro Ser Ala Asn Met Pro Trp Phe Lys Gly Trp Lys Val Thr Arg
                 215                 220                 225

 Lys Asp Gly Asn Ala Ser Gly Thr Thr Leu Leu Glu Ala Leu Asp
                 230                 235                 240

 Cys Ile Leu Pro Pro Thr Arg Pro Thr Asp Lys Pro Leu Arg Leu
                 245                 250                 255

 Pro Leu Gln Asp Val Tyr Lys Ile Gly Gly Ile Gly Thr Val Pro
                 260                 265                 270

 Val Gly Arg Val Glu Thr Gly Val Leu Lys Pro Gly Met Val Val
                 275                 280                 285

 Thr Phe Ala Pro Val Asn Val Thr Thr Glu Ser Lys Ile Cys Arg
                 290                 295                 300

 Asn Ala Pro


<210> 4565
<211> 3710
<212> DNA
<213> Homo sapien

<400> 4565
 catgtactgc accctcatct gtcaatctgt ctatcctgta taagttggga 50

 tgaatcattt tcattagatg aacaagtggc tgagacttta tctgacacat 100

 ggcatataca cgatcatcca gccgtgtgct tgtacccgtt ctaaatgctt 150

 tctgtttgag aagggccaaa acatagagag gaaacaactt gagggagctt 200

 ttttgttttt cttggcaaat tttaataact atattttgat tatactgtag 250

 aatgctatgt cagcataagt aagctaaact tgaagctttc ttgtgaagaa 300

 taaatgcaag atagaataca tcttctattt tttgtggtac caaaaatcac 350

 catcccctca agagtgttca tgtatagaac attctctaat gctgaagagt 400

 aaaacattat agcaacacta tgtaaatgta ttgaacagta tcaaagaaat 450

 agtctctaaa ttgtttgtac catatttttt tttctaaact taacataatt 500

 tttagcttta gtttcagtca aaactttgtc ttttctctcc cgagagcctt 550

 agaggttaaa atgcaatcag cctaccgtgt aaggagatgt tgtccatgta 600

 ctttctccag ccagttgggg gatcattgca gctcaggcct ggtgaactca 650

 gagattccat tcaatattaa gaatgggatt gttgaatttt actcacagag 700

 aaatcactgt ttcttcatgt tgtaagatgt tttctgtttg tgtatttgta 750

 tcatggttac tcatcaaaag ctctcattct gcctttgtag aattcagttc 800

 ccttcctttc atcatagcta aagtgacttt tttccctact attaacgtga 850

 tcctacatcc ttaaatctca tcgattacct cacttaggcc tgtggaacct 900

 tggcccttgg tcggtgtcct tggtgtcttc taagcaaggc tgtgcgttgt 950

 tcagaaacgt ggccagacca catttcctgc tgctcccatg ccgcatgcca 1000

 ggtggcctga gacagagctc cccatacggc tgcaaggtgc tttacctgtg 1050

 ggctttggca gtaacccaag agaggatcag aaggtggaga aggtgccacg 1100

 agtgatttaa caggcctgcc acagggagtg ccccccgccc agctcgttct 1150

 cagcacaggt tttctctttg ggagtaccca ggtgatttct agtgacccaa 1200

 ttttgtgtca tctccctgtt ttagccccac ttgcctagag acaactgttt 1250

 ccgatgcctt ttctgcttat catactagtt tctaaccacg cagatttctc 1300

 aaaatcattt attcaatgta ttttatttga gcacttagtg tattgagcta 1350

 ggcaggatat agggtgccgg agatacagcg atgaacaaga caggcaaaac 1400

 ttctgctttc ctaaaacttg tgatgagaga gaacaataaa aaagtgttgc 1450

 tgccacaaag aaaccaaagt gtgtggggaa gggcgcgtgt ttgcggttta 1500

 catctcttct gtcccagaat cacagggatc tggtccggtc acctctggtc 1550

 tttcctctta gtcgccttta ggagccctgg ttcccgtcca tcctctgggg 1600

 ggtttgtttg aagagatctc gtgtgggtac ttgtcatgaa aacaccttgg 1650

 gcatcatctg gtgtatccag ttctagtctc gagaattctg gtttcccact 1700

 gtgctcagca agtggaaagt tcttttcagg ccagaacagc tctgcaccat 1750

 cacatatcgt gttgcggctt agctgtttgg tctgtagttc aggttatggg 1800

 acttctccaa tcctggaagg ctgttgagct ttttagaagt actgtacgct 1850

 atcttcaaga tggagcttgg tcacatctgt taggaatcca aaggacacta 1900

 tgacttattt aaatcttgtc ttactaaacc tctcttgggc acgtgtgcca 1950

 gaatttctct tgttgcttct tgagccaccg cacccggcct aatctcagtt 2000

 tttgaagtgc tccacaagtc attaggcacc aaaacatttt cacctgggga 2050

 acactggcat ttccctgatt agctgtgaag caatctagtg gctaagtgtg 2100

 aaatcctggg tgcgcaggtg ttctcactcc cgccgtgttc tcagtgcagt 2150

 ggtggtcaga ggcccttcca aggagacatc actctgatca gttacagata 2200

 gatgttctgg aagatctgca ggtgagtaga tccagcagag tttcttccca 2250

 ccaactctag aagaaagggc cttatcagag ttgaccctga gcctttggta 2300

 aggttttgtg tgcatgcgat tcagttatct ttggcaattc ttttcttgct 2350

 gcagtgagag attaattggt tgctgatcaa accgttcatg cagatggggg 2400

 gacctttgga ttgtacggct ttctcctctt ggctgctttc ttttcaggaa 2450

 gttggacttt ggccaggttt ggctttccca gagccgttcc tttctctgtc 2500

 ctttccttgg gtcctcatgg tgtgcccatt ggatccttgg ccttgtgatc 2550

 ctctgggaac tgggggccag ttccactttt gcagccttct gtgctggaag 2600

 agaagcccag cgccctggaa ggagcctctt taagtccccc atgtcgcttt 2650

 ctctctctgc tcttttagtg tctgagattg cctttctttg aatttcccag 2700

 tgtttctttt ccttgtccct tccctcacca acctggagtt attttggttg 2750

 actatgtcct ggctttggct tctcctggca ggaagtcatc aggcatcctc 2800

 tccaggtgag ccgaaattcc accctcccag gttggacatc atcttttaaa 2850

 cccaatggtc tactcccctc cttctttatg aaacagtgat ttcccgtgag 2900

 taactctggt tctgattttt tgtaccggcg cttaaattct ttctgtagac 2950

 attggaaagc cacaaagaac gtgactgcag tgagcctccc actggagcag 3000

 ccttaaccaa cactttggcc aaagcccccc cacctcccct gtgtactgtg 3050

 tgtgtgtttg gtggatacag tattcctttt cagtgtccct aaagctgtga 3100

 tggggagtcc ccacttacct agaaagcatt accagtcacc tactctgcat 3150

 tctcagatgt aaaccttgtg tagtgttctt tttgcaatga cctatttatt 3200

 taacctattt atatttattt aatttttact ctgaaatgta tccagttaca 3250

 attgtacttg cttaaagcac atcagatttg ttttggacaa cacccttgac 3300

 cattttaaaa ctggaaaagt gatactgtat ccttccatgg gatggatgct 3350

 ttacagtagt cttattatta aagggtgatt aatttggtcg gggtaaaatg 3400

 ttaattttta ggtgattttt aagaattctg tgccattatg tcttctgtgt 3450

 ggatggttaa ttgtttaatt agtacgtgtt aattgtgtga tacagtcttc 3500

 tttgtggaac ccaaaatcct ctttttagct ttatatttta taaactgcca 3550

 gattgtacaa cttttatgtg catttttaaa gcttgaagac atgagggtca 3600

 ttatctaagt taaacagcct atttttgtgc ctcctgtaca gttttataat 3650

 tctgctgatg gcggcatctt atgtcgagcc aaccacaata aaggtagttt 3700

 tagattttgg 3710

<210> 4566
<211> 47
<212> PRT
<213> Homo sapien

<400> 4566
 His Val Leu His Pro His Leu Ser Ile Cys Leu Ser Cys Ile Ser
   1               5                  10                  15

 Trp Asp Glu Ser Phe Ser Leu Asp Glu Gln Val Ala Glu Thr Leu
                  20                  25                  30

 Ser Asp Thr Trp His Ile His Asp His Pro Ala Val Cys Leu Tyr
                  35                  40                  45

 Pro Phe


<210> 4567
<211> 4092
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1873-1896
<223> Unknown base

<400> 4567
 ggaccacctt tactctgtgg caaggatgga acagtgggta gaatatgaag 50

 atgaatgaga ctcagtactg ccttcaaggg agaagcagac atacacagag 100

 ctctctatca atatcagctc acatcattga aaagataatt ttgaagacat 150

 gttttgctga aaagacacta agaaaaattt tacgaatggg atgaacatgc 200

 tccagttaat tgactaccta ctgcaatttg aatgttaaca ttacccatct 250

 ggtacagtta cctagtgatg tacctatttt cacaataccc tgtttcagtg 300

 tgcttgtctt gattaaagaa ttcaaagtgg agtaccgcaa acttgatatg 350

 gaaaataaaa agaaagacaa ggacaaatca gatgatagaa tggcacgacc 400

 tagtggtcga tcgggacaca acactcgagg aactgggtct tcatcgtctg 450

 gagttttaat ggttggacct aactttagag ttggaaaaaa aattggatgt 500

 ggcaatttgg agaattacga ttagggaaaa atttatacac aaatgaatat 550

 gtggcaatta agttggagcc catgaaatca agagcaccac agctacattt 600

 ggaatacaga ttctataagc agttaggatc tggagatggt atacctcaag 650

 tttactattt cggcccttgt ggtaaataca atgctatggt gctggaactg 700

 ctgggaccta gtttggaaga cttgtttgac ttgtgtgaca gaacattttc 750

 tcttaaaaca gttctcatga tagctataca actgatttct cgcatggaat 800

 atgtccattc aaagaacttg atatacagag atgtaaaacc tgagaacttc 850

 ttaataggac gaccaggaaa caaaacccag caagttattc acattataga 900

 ttttggtttg gcaaaggaat atattgatcc ggagacaaag aaacacatac 950

 catacagaga acacaagagc cttacaggaa cagctagata tatgagcata 1000

 aacacacatt taggaaaaga acaaagtaga agagacgatt tagaagcttt 1050

 aggtcatatg ttcatgtatt ttctgagagg cagtcttcct tggcaaggct 1100

 taaaggctga cacattaaag gagaggtatc agaaaattgg agatacaaaa 1150

 cgggctacac caatagaagt gttatgtgaa aattttccag aagaaatggc 1200

 aacatatctt cgttatgtaa gaaggctaga tttttttgaa aaaccagact 1250

 atgactactt aagaaagctt tttactgact tgtttgatcg aaaaggatat 1300

 atgtttgatt atgaatatga ctggattggt aaacagttgc ctactccagt 1350

 gggtgcagtt cagcaagatc ctgctctgtc atcaaacaga gaagcacatc 1400

 aacacagaga taagatgcaa caatccaaaa accagtcggc agaccacagg 1450

 gcagcttggg actcccagca ggcaaatccc caccatttga gagctcacct 1500

 tgcagcagac agacatggtg gctcggtaca ggttgtaagt tctacaaatg 1550

 gagagttaaa cacagatgac cccaccgcag gacgttcaaa tgcacccatc 1600

 acagccccta ctgaagtaga agtgatggat gaaaccaact gccagaaagt 1650

 gttgaacatg tggtgctgct gctttttcaa acgaaggaaa aggaaaacca 1700

 tacagcgcca caaatgactc tggacacaga cagatcctgg ggagttactt 1750

 acatgttcat ctgctgtctt gtgattaaaa tcatctctgt agtgaccacg 1800

 tatattttca aggactcact cttagaaaca aaaatgtcat actatcatac 1850

 ttcattttgt ggttgtctta cannnnnnnn nnnnnnnnnn nnnnnnaatt 1900

 taacctttat ggaagcttta aagttttgtc aaaacatgag tgctttgccc 1950

 atcagtgaat ggaatggacc aatgaggtgg tatcaatgaa tatagttcca 2000

 tagaacattt tccagaagtt cttctgttgt agaaagcagt acagtatctt 2050

 aagtgtcaac cagttatata cctaatctgg tttttttata acttctgtaa 2100

 gagcataatc aaacaggaat tttcttttct cagtggataa tacaacagag 2150

 aaaacagagt tgcccaaata tttaaaagaa gttattcctt gagaagttca 2200

 tattttgtga catctgcatt gatttcagta ttactgatgg tactgttatt 2250

 cataagtcat attaacattc tctccgtgaa atcatggtac agtcactgcc 2300

 cagaggtact gaggaaaaag caatatgggt tcggcagatg gtggtggtaa 2350

 aatgaatctt aaggagtgtg gtaaatatgt gctccgcttt tgttgcatca 2400

 ctatgtgaag tactgtgttg cagaagtggc aaaagcgctt atttttaaaa 2450

 atgcaaaata tttgtacaat gtaactttat gcttccaaat aataatgtat 2500

 gttagacagc aagaaatgaa tactttaaaa agtgatatat gttggagtta 2550

 taaagaaata cactaaggag aggtagtaaa tgtgaacctt gttgcagtgt 2600

 ataaggtgga agcctaaaga aatctcaccg aaacttactg ctgaatgatt 2650

 acattctccc ttaagcagaa aactttggat gtgccatgca atggtgtctg 2700

 tgtaattatt ttgctctttg attaaaaaaa agacccccag caataaaaag 2750

 tgggtcactc tatgccctct gtgcacatta gtctcttgta ttcaactttg 2800

 ctgattctct ggaattttcc tactctttag cataattttg atgattgaaa 2850

 aatattttgg aaaggatggg tcaggtgctt tgcctccata gtcttttgaa 2900

 gtgcctgcat atgaacaaca aaacaaaagc aaaaaattct gtaaaaaagg 2950

 aagcccattc cacttttcaa gtatgctttg ttttaagcca taaagacaca 3000

 catgtagttt tgtcacattc tactagccaa aattttcaag aagggttaaa 3050

 acaaagactg gctagaaaga taattatttt gaataaatct catattcatc 3100

 tttcatttat ataattgtta cttattcctc ccatgcagtc tcttcgttgt 3150

 ctttaagtgt gtgcctccag gcatgcttat ttatttttat tgtctcaagg 3200

 taacatttaa gatgtatatt aaagtaaagc tacatttttt tacttcatta 3250

 ttgcatttac agggatttaa ttgtactttg taatttattt ttcttattag 3300

 ccaaaagttt aatgcatttt tttttgatga attaggcacc cacatgaaca 3350

 ccacaaatca ggacattgtt tatcattgtt gctatgaatc ctatgaatga 3400

 tctttttttt attttaaaga cctacactta acctacaaaa catttgctgt 3450

 ataatttggt caacagtttc tatctatctg tatactgtca tgatgtctta 3500

 aactgcagga gttacatact gagtttatat ttttatttgc tttgagcaag 3550

 gtagataaac attttggcca ttataatgtg aaaccacttc ttctttcttt 3600

 acagtatttg accaaacttg tgtgtctatg atatttgtaa atacatgcga 3650

 atatctgtat ttcttatcat aagcctattt agttttattc tcagtagggt 3700

 tttttggatt gtacagtgtt tatatgatct gaactcctta tacataagaa 3750

 ggtgtgtata ttaatccaat tatggactta aaatatttta aaagtataaa 3800

 tacccttatt tgctgcaaag accagtgtgt aggcatttgc tttttagcaa 3850

 tatttttaag tgctccattt taatgccgag gaataagtct tttggcaaca 3900

 caaactggtc aataataggt aatgcaggta tgttcaggtt aagccaacaa 3950

 tgttttgcat ttttatgctt attttctgtc aacactaatg aagtcaacat 4000

 tgcctgaatg tctgaataat gaaacacatc cctgtttaaa agtatgtaac 4050

 tgaaaaagaa ataaaaaaaa ataaaagtag tttttttaaa aa 4092

<210> 4568
<211> 381
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1873-1896
<223> Unknown amino acid

<400> 4568
 Met Lys Ser Arg Ala Pro Gln Leu His Leu Glu Tyr Arg Phe Tyr
   1               5                  10                  15

 Lys Gln Leu Gly Ser Gly Asp Gly Ile Pro Gln Val Tyr Tyr Phe
                  20                  25                  30

 Gly Pro Cys Gly Lys Tyr Asn Ala Met Val Leu Glu Leu Leu Gly
                  35                  40                  45

 Pro Ser Leu Glu Asp Leu Phe Asp Leu Cys Asp Arg Thr Phe Ser
                  50                  55                  60

 Leu Lys Thr Val Leu Met Ile Ala Ile Gln Leu Ile Ser Arg Met
                  65                  70                  75

 Glu Tyr Val His Ser Lys Asn Leu Ile Tyr Arg Asp Val Lys Pro
                  80                  85                  90

 Glu Asn Phe Leu Ile Gly Arg Pro Gly Asn Lys Thr Gln Gln Val
                  95                 100                 105

 Ile His Ile Ile Asp Phe Gly Leu Ala Lys Glu Tyr Ile Asp Pro
                 110                 115                 120

 Glu Thr Lys Lys His Ile Pro Tyr Arg Glu His Lys Ser Leu Thr
                 125                 130                 135

 Gly Thr Ala Arg Tyr Met Ser Ile Asn Thr His Leu Gly Lys Glu
                 140                 145                 150

 Gln Ser Arg Arg Asp Asp Leu Glu Ala Leu Gly His Met Phe Met
                 155                 160                 165

 Tyr Phe Leu Arg Gly Ser Leu Pro Trp Gln Gly Leu Lys Ala Asp
                 170                 175                 180

 Thr Leu Lys Glu Arg Tyr Gln Lys Ile Gly Asp Thr Lys Arg Ala
                 185                 190                 195

 Thr Pro Ile Glu Val Leu Cys Glu Asn Phe Pro Glu Glu Met Ala
                 200                 205                 210

 Thr Tyr Leu Arg Tyr Val Arg Arg Leu Asp Phe Phe Glu Lys Pro
                 215                 220                 225

 Asp Tyr Asp Tyr Leu Arg Lys Leu Phe Thr Asp Leu Phe Asp Arg
                 230                 235                 240

 Lys Gly Tyr Met Phe Asp Tyr Glu Tyr Asp Trp Ile Gly Lys Gln
                 245                 250                 255

 Leu Pro Thr Pro Val Gly Ala Val Gln Gln Asp Pro Ala Leu Ser
                 260                 265                 270

 Ser Asn Arg Glu Ala His Gln His Arg Asp Lys Met Gln Gln Ser
                 275                 280                 285

 Lys Asn Gln Ser Ala Asp His Arg Ala Ala Trp Asp Ser Gln Gln
                 290                 295                 300

 Ala Asn Pro His His Leu Arg Ala His Leu Ala Ala Asp Arg His
                 305                 310                 315

 Gly Gly Ser Val Gln Val Val Ser Ser Thr Asn Gly Glu Leu Asn
                 320                 325                 330

 Thr Asp Asp Pro Thr Ala Gly Arg Ser Asn Ala Pro Ile Thr Ala
                 335                 340                 345

 Pro Thr Glu Val Glu Val Met Asp Glu Thr Asn Cys Gln Lys Val
                 350                 355                 360

 Leu Asn Met Trp Cys Cys Cys Phe Phe Lys Arg Arg Lys Arg Lys
                 365                 370                 375

 Thr Ile Gln Arg His Lys
                 380

<210> 4569
<211> 2485
<212> DNA
<213> Homo sapien

<400> 4569
 atggcgaacg cgagcgagcc gggtggcagc ggcggcggcg aggcggccgc 50

 cctgggcctc aagctggcca cgctcagcct gctgctgtgc gtgagcctag 100

 cgggcaacgt gctgttcgcg ctgctgatcg tgcgggagcg cagcctgcac 150

 cgcgccccgt actacctgct gctcgacctg tgcctggccg acgggctgcg 200

 cgcgctcgcc tgcctcccgg ccgtcatgct ggcggcgcgg cgtgcggcgg 250

 ccgcggcggg ggcgccgccg ggcgcgctgg gctgcaagct gctcgccttc 300

 ctggccgcgc tcttctgctt ccacgccgcc ttcctgctgc tgggcgtggg 350

 cgtcacccgc tacctggcca tcgcgcacca ccgcttctat gcagagcgcc 400

 tggccggctg gccgtgcgcc gccatgctgg tgtgcgccgc ctgggcgctg 450

 gcgctggccg cggccttccc gccagtgctg gacggcggtg gcgacgacga 500

 ggacgcgccg tgcgccctgg agcagcggcc cgacggcgcc cccggcgcgc 550

 tgggcttcct gctgctgctg gccgtggtgg tgggcgccac gcacctcgtc 600

 tacctccgcc tgctcttctt catccacgac cgccgcaaga tgcggcccgc 650

 gcgcctggtg cccgccgtca gccacgactg gaccttccac ggcccgggcg 700

 ccaccggcca ggcgaccgcc aactggacgg cgggcttcgg ccgcgggccc 750

 acgccgcccg cgcttgtggg catccggccc gcagggccgg gccgcggcgc 800

 gcgccgcctc ctcgtgctgg aagaattcaa gacggagaag aggctgtgca 850

 agatgttcta cgccgtcacg ctgctcttcc tgctcctctg ggggccctac 900

 gtcgtggcca gctacctgcg ggtcctggtg cggcccggcg ccgtccccca 950

 ggcctacctg acggcctccg tgtggctgac cttcgcgcag gccggcatca 1000

 accccgtcgt gtgcttcctc ttcaacaggg agctgaggga ctgcttcagg 1050

 gcccagttcc cctgctgcca gagcccccgg accacccagg cgacccatcc 1100

 ctgcgacctg aaaggcattg gtttatgagg gaggccccgc cacatagacc 1150

 cccaacccag cctttccctt tggctcggac ggtgacgttg tatcttttcc 1200

 ttctggcccc tgtttaattt tctaagctgc cttcaaaatg actcgaagtg 1250

 gacagacact tggattgtac tgactccttt gggggtgggg tgggtgagga 1300

 gtaggatgct cagcccactc cagctccgca cattcgtcct cctaactcga 1350

 ctttcttcct gacaataggc cctgcagtct ttttgtagcg gtactgacgt 1400

 cttttattcc atgtgtggtt cctttttttc tttttctata aaggctgtac 1450

 taattttctt catgcaacgt ttcctaaaga ccatggccag ttttctacag 1500

 aagctatttt tgacaacctc aagtggcatt acattttgca gtgaagtaga 1550

 ggaacctagg gggacttctt cacaagttag atttcttgag gatcttctgt 1600

 tggaagcagg agaaagtggg gggtgggggg aagttgtccg aaatgccctc 1650

 tgaattgccg gctgcagggt ccttgtgctg cgctggttct ttgaaagtct 1700

 cagtgttgat attgaactta aagagcagag atggagatca gtagcaaggc 1750

 agtcattttt ttaaagcagt aagtaacaag taagatttgg ttcccggttt 1800

 actttctgct gctaaaaacc acgtcagtga caactgctct ctgtattata 1850

 gcaatcttga atggaaacat ttctgtcaag ttgtaagttt taaaagagta 1900

 aagtgttttg gttagtaatg atgtggagaa aaatacagta ttgcatgtgt 1950

 tcgtgtgtat agattgtggt tcgaggattg ggagggctct gagaagcaga 2000

 gtactacatc aaaattgttt taagtatttt ttgccaataa aaaattaatt 2050

 ttatggaaat ggcttgtgct ttgagaagcc cagttttatt ctgtcttatg 2100

 aaactaattt ccactttgaa aattgttctt ctgttgttta tggtataaat 2150

 gaatggaata taatgatatc ctccttctag gaaacaaagc atttccttaa 2200

 aatgtttgct aggttaagct gtgctgttct actgatggtt gttttaaatt 2250

 aataatgaga actataattt aaataatatt tctttgttag acattataat 2300

 gttaaactga aagactaaat tctgcaagta ctatataata tttttggctt 2350

 ataatgctac atttttatta atgtaccttc cgttttgagg atttatatct 2400

 gtatttctct ttgcattata caaatatacc agtattttca aaaaaaatct 2450

 atgtcgggtg cggagaaaga ggtaatgaaa tggca 2485

<210> 4570
<211> 375
<212> PRT
<213> Homo sapien

<400> 4570
 Met Ala Asn Ala Ser Glu Pro Gly Gly Ser Gly Gly Gly Glu Ala
   1               5                  10                  15

 Ala Ala Leu Gly Leu Lys Leu Ala Thr Leu Ser Leu Leu Leu Cys
                  20                  25                  30

 Val Ser Leu Ala Gly Asn Val Leu Phe Ala Leu Leu Ile Val Arg
                  35                  40                  45

 Glu Arg Ser Leu His Arg Ala Pro Tyr Tyr Leu Leu Leu Asp Leu
                  50                  55                  60

 Cys Leu Ala Asp Gly Leu Arg Ala Leu Ala Cys Leu Pro Ala Val
                  65                  70                  75

 Met Leu Ala Ala Arg Arg Ala Ala Ala Ala Ala Gly Ala Pro Pro
                  80                  85                  90

 Gly Ala Leu Gly Cys Lys Leu Leu Ala Phe Leu Ala Ala Leu Phe
                  95                 100                 105

 Cys Phe His Ala Ala Phe Leu Leu Leu Gly Val Gly Val Thr Arg
                 110                 115                 120

 Tyr Leu Ala Ile Ala His His Arg Phe Tyr Ala Glu Arg Leu Ala
                 125                 130                 135

 Gly Trp Pro Cys Ala Ala Met Leu Val Cys Ala Ala Trp Ala Leu
                 140                 145                 150

 Ala Leu Ala Ala Ala Phe Pro Pro Val Leu Asp Gly Gly Gly Asp
                 155                 160                 165

 Asp Glu Asp Ala Pro Cys Ala Leu Glu Gln Arg Pro Asp Gly Ala
                 170                 175                 180

 Pro Gly Ala Leu Gly Phe Leu Leu Leu Leu Ala Val Val Val Gly
                 185                 190                 195

 Ala Thr His Leu Val Tyr Leu Arg Leu Leu Phe Phe Ile His Asp
                 200                 205                 210

 Arg Arg Lys Met Arg Pro Ala Arg Leu Val Pro Ala Val Ser His
                 215                 220                 225

 Asp Trp Thr Phe His Gly Pro Gly Ala Thr Gly Gln Ala Thr Ala
                 230                 235                 240

 Asn Trp Thr Ala Gly Phe Gly Arg Gly Pro Thr Pro Pro Ala Leu
                 245                 250                 255

 Val Gly Ile Arg Pro Ala Gly Pro Gly Arg Gly Ala Arg Arg Leu
                 260                 265                 270

 Leu Val Leu Glu Glu Phe Lys Thr Glu Lys Arg Leu Cys Lys Met
                 275                 280                 285

 Phe Tyr Ala Val Thr Leu Leu Phe Leu Leu Leu Trp Gly Pro Tyr
                 290                 295                 300

 Val Val Ala Ser Tyr Leu Arg Val Leu Val Arg Pro Gly Ala Val
                 305                 310                 315

 Pro Gln Ala Tyr Leu Thr Ala Ser Val Trp Leu Thr Phe Ala Gln
                 320                 325                 330

 Ala Gly Ile Asn Pro Val Val Cys Phe Leu Phe Asn Arg Glu Leu
                 335                 340                 345

 Arg Asp Cys Phe Arg Ala Gln Phe Pro Cys Cys Gln Ser Pro Arg
                 350                 355                 360

 Thr Thr Gln Ala Thr His Pro Cys Asp Leu Lys Gly Ile Gly Leu
                 365                 370                 375

<210> 4571
<211> 923
<212> DNA
<213> Homo sapien

<400> 4571
 cgctgaggcc ccacagcctc ccaattccgg gcagacccct gacacctgct 50

 gtctggcccc ttccggcctg aagctgcagc cgcgccatgt ccacccctcc 100

 gttggccgcg tcggggatgg cgcccgggcc cttcgccggg ccccaggctc 150

 agcaggccgc ccgggaagtc aacacggcgt cgctgtgccg catcgggcag 200

 gagacagtgc aggacatcgt gtaccgcacc atggagatct tccagctcct 250

 gaggaacatg cagctgccaa atggtgtcac ttaccacact ggaacatatc 300

 aagaccggtt aacaaagcta caggataatc ttcgccaact ttcagttctc 350

 ttcaggaagc tgagattggt atatgacaaa tgcaatgaaa actgtggtgg 400

 gatggatccc attccagtcg agcaacttat tccatatgtg gaagaagatg 450

 gctcaaagaa tgatgatcgg gctggcccac ctcgttttgc tagtgaagag 500

 aggcgagaaa ttgctgaagt aaataaaaaa ctcaaacaga agaatcaaca 550

 gctgaaacaa attatggatc aattacgaaa tctcatctgg gatataaatg 600

 ccatgttggc aatgaggaac taagctgata tttaaatttc ctgctttaca 650

 catgttatac cattgttttt ttccctcaag tattttttcc ctgtgaagaa 700

 gattatttat ctgcttttat tttagtcact aaaactaaag tttttatttt 750

 tacattgtga tttttacatt aaaatattaa ctttttttaa tgctatttta 800

 tgaaagatta ttgtaataaa ctttgatggg gtttgtattt tggttaatct 850

 tcatgaattg aataattgtt tttttaaagc aaaataaagt tttttaaata 900

 aatgttaaaa aaaaaaaaaa aaa 923

<210> 4572
<211> 178
<212> PRT
<213> Homo sapien

<400> 4572
 Met Ser Thr Pro Pro Leu Ala Ala Ser Gly Met Ala Pro Gly Pro
   1               5                  10                  15

 Phe Ala Gly Pro Gln Ala Gln Gln Ala Ala Arg Glu Val Asn Thr
                  20                  25                  30

 Ala Ser Leu Cys Arg Ile Gly Gln Glu Thr Val Gln Asp Ile Val
                  35                  40                  45

 Tyr Arg Thr Met Glu Ile Phe Gln Leu Leu Arg Asn Met Gln Leu
                  50                  55                  60

 Pro Asn Gly Val Thr Tyr His Thr Gly Thr Tyr Gln Asp Arg Leu
                  65                  70                  75

 Thr Lys Leu Gln Asp Asn Leu Arg Gln Leu Ser Val Leu Phe Arg
                  80                  85                  90

 Lys Leu Arg Leu Val Tyr Asp Lys Cys Asn Glu Asn Cys Gly Gly
                  95                 100                 105

 Met Asp Pro Ile Pro Val Glu Gln Leu Ile Pro Tyr Val Glu Glu
                 110                 115                 120

 Asp Gly Ser Lys Asn Asp Asp Arg Ala Gly Pro Pro Arg Phe Ala
                 125                 130                 135

 Ser Glu Glu Arg Arg Glu Ile Ala Glu Val Asn Lys Lys Leu Lys
                 140                 145                 150

 Gln Lys Asn Gln Gln Leu Lys Gln Ile Met Asp Gln Leu Arg Asn
                 155                 160                 165

 Leu Ile Trp Asp Ile Asn Ala Met Leu Ala Met Arg Asn
                 170                 175

<210> 4573
<211> 1079
<212> DNA
<213> Homo sapien

<400> 4573
 caccttggta acatactgtt gatatcaaga acctgtttag tttacattgt 50

 aacattctat tgtaaaatca actaaaattc agacttttag caggactttg 100

 tgtacagtta aaggagagat ggccaagcca gggacaaatt gtctattaga 150

 aaacggtcct aagagattct ttggtgtttg gcactttaag gtcatcgttg 200

 ggcagaagtt tagcattaat agttgttctg aaacgtgttt tatcaggttt 250

 agagcccatg ttgagtcttc ttttcatggg ttttcataat attttaaaac 300

 tatttgttta gcgatggttt tgttcgttta agtaaaggtt aatcttgatg 350

 atatacataa taatctttct aaaattgtat gctgaccata cttgctgtca 400

 gaataatgct aggcatatgc tttttgctaa atatgtatgt acagagtatt 450

 tggaagttaa gaattgatta gactagtgaa tttaggagta tttgaggtgg 500

 gtggggggaa gagggaaatg acaactgcaa atgtagacta tactgtaaaa 550

 attcagtttg ttgctttaaa gaaacaaact gatacctgaa ttttgctgtg 600

 tttccatttt ttagagattt ttatcatttt tttctctctc ggcattcttt 650

 tttctcatac tcttcaaaaa gcagttctgc agctggttaa ttcatgtaac 700

 tgtgagagca aatgaataat tcctgctatt ctgaaattgc ctacatgttt 750

 caataccagt tatatggagt gcttgaattt aataagcagt ttttacggag 800

 tttacagtac agaaataggc tttaattttc aagtgaattt tttgccaaac 850

 ttagtaactc tgttaaatat ttggaggatt taaagaacat cccagtttga 900

 attcatttca aactttttaa atttttttgt actatgtttg gttttatttt 950

 ccttctgtta atcttttgta ttcacttatg ctctcgtaca ttgagtactt 1000

 ttattccaaa actagtgggt tttctctact ggaaattttc aataaacctg 1050

 tcattattgc ttaaaaaaaa aaaaaaggg 1079

<210> 4574
<211> 47
<212> PRT
<213> Homo sapien

<400> 4574
 Met Phe Gly Phe Ile Phe Leu Leu Leu Ile Phe Cys Ile His Leu
   1               5                  10                  15

 Cys Ser Arg Thr Leu Ser Thr Phe Ile Pro Lys Leu Val Gly Phe
                  20                  25                  30

 Leu Tyr Trp Lys Phe Ser Ile Asn Leu Ser Leu Leu Leu Lys Lys
                  35                  40                  45

 Lys Lys


<210> 4575
<211> 2594
<212> DNA
<213> Homo sapien

<400> 4575
 aaaagattga ccttgaaaag aatctctctg cttctgaagt tgaagtccag 50

 ctcatcagag agtcgctcaa agtggcgttg cagaagcatt ctgaggaagt 100

 gaagaaacag gaagaaaggg tcaaaggtcg tgataaacat atcaataatt 150

 tgaaaaagaa atgccagaag gaatcagagc agaaccggga gaagcagcag 200

 cgtattgaga ccttggagcg ctacctggct gacctgccca cactggaaga 250

 ccatcagaag cagagccagc agcttaagga ttctgagttg aagagcacag 300

 agctgcagga gaaagtgact gagctggaga gtttgctgga ggagacccag 350

 gcaatctgca gagagaagga gattcaactg gaaagcctga ggcagagaga 400

 agcagaattc tcctccgctg gacatagcct gcaagataaa cagtctgtgg 450

 aggagaccag tggagaaggt ccagaagtgg aaatggagtc ctggcagaag 500

 cgatacgatt cgctccaaaa gattgtggag aagcagcagc agaagatgga 550

 tcagttgcgc tcacaagtac agagcctaga gcaggaagtg gctcaagaag 600

 aaggaacaag ccaggccctg agagaggagg cccagcgaag ggattcagcc 650

 ctgcagcact ggcgcacagc cgtgaaggag ctttcagtgc aaaaccagga 700

 cttgattgag aagaatctga cactccagga acacctgcgc caggcccaac 750

 cagggtctcc accttcacca gacacggccc agctggcact tgagctgcac 800

 caggagttgg ccagttgcct tcaagatctg caggctgtct gtagcattgt 850

 gacccagagg cccagggcca tgaccccaat ctctccctgc tcctgggcat 900

 tcactcagca cagcacccag agactcagct agatttgcag aagccagatg 950

 tgatcaagag gaaactagaa gaggttcaac agctgcgtcg tgacattgag 1000

 gacttaagga ccaccatgtc agacagatat gcccaggaca tgggagaaaa 1050

 ctgtgtcaca cagtgaggaa ttctggggat tccccaggga ggagctgggc 1100

 tgctgagagc ctagtccagc aggtttctgc cctgacattc tcttgtctgc 1150

 tattcccaga gaggtctcag aggggagggg agagcctgca tctgggggcc 1200

 aagggctgat tagggaactg tgtcctaccc acactggcat gttggattac 1250

 gtttgtcctg ttaattcact ctcgacggtg agttactaat taacttttgg 1300

 caggtacaac agataagtcc tcacaaactg ttcccagccc taggctgaca 1350

 tgagagacga acaggctgtc cacctttctt ctccatccaa tgggatggat 1400

 ccatgttcat tcccacttca caccttggtc ctgctgatta gagagctcat 1450

 cagaggggcc tggaaaggct gagcaagtac cagtgacaat ggccatttaa 1500

 gaattctcag gccccatgtg ccagccttct tgggaactga gctggctttc 1550

 tgggttttct catgcctggt cttactgctt cttcctcagg gctcttgttc 1600

 tcccagaagc ctcagggtaa tgtgttggtt agcacgtaac tactaggatt 1650

 ggggccctag ggattatagc caggactcta atctgcctac catgccattt 1700

 aacaagagat cccactctcc agctgccttg tgtccctagg gtcctggcca 1750

 tgtgtttagt gtgctaaact ttctcctttg ttctcaggcc ttccaggtag 1800

 tccccttcct ggacttaaga gtgcaaactc ttctctgtgg ttctagcctt 1850

 gggcagaatt atatcccaga gaccacagag caactgtcaa gctgcttacc 1900

 ccctcaccca gggctacagc ctgtgcccag ccctctaatt tgtgcctctc 1950

 ttgtgttggg ggtggtgggg gttattcctt tccctttcct gctctggcct 2000

 ccttgaaagt tcagagtacc cagtacaagt cagctttaaa gtacagcttt 2050

 tagtgtttcc tgggttgttt ctctggggct ttagtgaggg acctttgccc 2100

 tctggttttt cttgcctcct ggtttaggga gcatctcaca cttgttagta 2150

 tctggttgtt gggccagccg tgcctcctct agatctggag ccaggccagg 2200

 caggggccac gtgtgggcca gtcagccact acaagatttt tgctaagctt 2250

 tgggctgttg gcagcatctt ggacctcatg cctgggcctg aatgaggctc 2300

 tttcttaagt gtttttacaa gtttgtgttt tatttatgga gtgacttatc 2350

 ccttccattc agagcagccc cacccagcca gcccttcagc ctctgggctc 2400

 ctgctgctta aaggcagagc cgcctggttg gtctccaccc tgtgcattgg 2450

 gagcccagcc accatgctga cgggtatttt tcctcataaa gtttataacc 2500

 agttatttat atgaatcttt gttatgtcca tttgtttgta ttgcgtattt 2550

 tgattataaa ataaagtatc ttaacagaca aaaaaaaaaa aaaa 2594

<210> 4576
<211> 2594
<212> DNA
<213> Homo sapien

<400> 4576
 tggtgcgtcg cggcgtggtc ctccggcggc tgtccggggc ggtaggagtt 50

 ggctgcggga tgtgctcagc cggggagctg ctgcggggcg gcgacggcgg 100

 ggaacgcgac gaggacgggg acgcgctggc ggagcgggag gcggcaggga 150

 ccgagtggga tcccggggcg agcccgcggc ggcgcggaca gcggccgaag 200

 gagagcgagc aggatgttga agactcacag aaccacactg gtgagccggt 250

 tggagatgac tacaagaaaa tgggaacact ttttggtgaa ctgaacaaaa 300

 accttatcaa catgggcttc acaaggatgt attttggaga acgaatagtg 350

 gaaccagtaa tagtcatttt cttttgggtt atgctgtggt tccttggcct 400

 gcaagccctt ggactagttg ctgttctttg ccttgttatt atttatgtgc 450

 aacagtaaaa catggccgaa ttgaattgtt tgacatttgg tagccatata 500

 tgtaattgaa gaagttatat atttcacttt ttgacaaccg aaaaagtttg 550

 ccttgtttca aatcatgtgc tggctgtttt gtaagtaaat ttatacatgg 600

 atgtcactta aaactaaact cttgatcata acagggttga atatatattt 650

 tgaatataca ttagcttatt caaaactctt gtttcactac tgtgatctct 700

 gtctccttta tacacctcta tccccatgcc aaatcttaag taacaccacc 750

 agaaagtgaa cagggaaaat aacaggacat ggaattcaaa tcaagcaata 800

 tagttcttat aaagagttcc aataaaacat ttcagaagaa aaagtatgaa 850

 acaagctaaa agtaagtttc acttagaaaa cttctcccca ctcacactcc 900

 ccaccaaata atctcatatt atttgggaaa tatttggatt tcaattgtcc 950

 ctacccagcc taaactaagg taaatgataa ttagcataca ctaccttaat 1000

 attgtgatga aaatcagtaa agatagaacg ttttctaaag gtcgaaaata 1050

 atatatttat tattactggg gaaagctccc aggttaaata taactttttt 1100

 aaaatgtaac atttggacct agacctactt taatatatca tttgaagttt 1150

 cagacaattt tggtgctaat tactttttgt gagtttttaa agtctcatag 1200

 cctagttgac tgcaccctat ggtaatgcca tattttcttg tatctaacaa 1250

 gttgcatatt ttttcctaga gagacatttt cagtgtattt tttttttaga 1300

 aatttataat tttatagttc tttcataaca cttattctga gttttgaaac 1350

 aatgtatttc ctatcttgac atggattttt tcacaaaaaa tttgtatttt 1400

 actgttgttt tcaggaaaaa aatcagatca tttttctttg atatctatat 1450

 cagaaaggta caatattaac agtataaaac caaatgctta aatttggaac 1500

 ttagccaatt ttgataatct ttttctaagg ctaaagtcac atcagtaatt 1550

 ggctagccat gttattaagg tgtcttaatt cagcattttc aggttttata 1600

 ttgaaatacg catttcttta aatattcttt gaaaatggag aatggcttta 1650

 gtgatatttt gggttttgtt agagaaccta aaatctttac actttcatct 1700

 caaagattat aaaggaaagg ggggtagtta agatttagaa ttcaagttaa 1750

 atttcagaaa ttggggcagt caggcatttg tatctttggt agggcaacaa 1800

 gtaaaacatg tagagtgctt gctatcccac ttcataaagc ttttacccaa 1850

 tcttatttct aaacctctgt gcattcttag tgtcttctca ttctgaaaca 1900

 gaaaataagg aaaaacattt aacttagttt tctaaaatca gataatccta 1950

 aacaaaaatg ttagtcaggg tcactaaaaa gtattgcaca tttatataaa 2000

 tacagtcctt ttaaaatttg acttttaaaa aacaaaagac tttgtacgat 2050

 attgtgtttt tattgcgttt gcaatatttt tatagtagcc tttatgaact 2100

 cagtataagt gcaagttgtt tgaaaaggtg tttttattag tgcacaatag 2150

 aattgtgagg ttttcaatag atgtcatgag attttgtata tctacataaa 2200

 atatcagtac atttttttct aatgctactg gaaattttac ttttcctttg 2250

 caacacataa atgatatgat gtacaaaata acagctctgg ttccaccagt 2300

 acctaatgtt gaaaacattt ttaaagtaat ttttaatact aactatttag 2350

 tatactgtca gtactgtaca tctgcacact ggtgttaata gggtatatat 2400

 taaattatat aaagaaataa gatattttgc tgttattctt tctacatata 2450

 ttattggtca gtacatcaaa taatatttgg ctttgatatg ggaaaaaaca 2500

 aactttgcct atgtaatgga aataaaatat tttcttttat gaaatatatt 2550

 agaatgcaga ttatactaat atcctgaaat aaaactggta attt 2594

<210> 4577
<211> 132
<212> PRT
<213> Homo sapien

<400> 4577
 Met Cys Ser Ala Gly Glu Leu Leu Arg Gly Gly Asp Gly Gly Glu
   1               5                  10                  15

 Arg Asp Glu Asp Gly Asp Ala Leu Ala Glu Arg Glu Ala Ala Gly
                  20                  25                  30

 Thr Glu Trp Asp Pro Gly Ala Ser Pro Arg Arg Arg Gly Gln Arg
                  35                  40                  45

 Pro Lys Glu Ser Glu Gln Asp Val Glu Asp Ser Gln Asn His Thr
                  50                  55                  60

 Gly Glu Pro Val Gly Asp Asp Tyr Lys Lys Met Gly Thr Leu Phe
                  65                  70                  75

 Gly Glu Leu Asn Lys Asn Leu Ile Asn Met Gly Phe Thr Arg Met
                  80                  85                  90

 Tyr Phe Gly Glu Arg Ile Val Glu Pro Val Ile Val Ile Phe Phe
                  95                 100                 105

 Trp Val Met Leu Trp Phe Leu Gly Leu Gln Ala Leu Gly Leu Val
                 110                 115                 120

 Ala Val Leu Cys Leu Val Ile Ile Tyr Val Gln Gln
                 125                 130

<210> 4578
<211> 1119
<212> DNA
<213> Homo sapien

<400> 4578
 acctttcagg atcctgctca catatcacct cttctgggag gtcttaccag 50

 gttgcagttt gatgtccagg ctatcccctt agctttgtga cttcaggtaa 100

 cttgctgcat tgttctgatc ttcagtgtca ttgtctctga aatgctactg 150

 atgctgccct gcctgccttg caggactgtt ggcaggcctg attccagaag 200

 ctctctagaa ctgtactgtg ctggacagat aggcaggggg cttggcaggg 250

 taatttcttg gttctagggt gtgtgtttgg ggagtatgtt tggtggtcct 300

 gagagctgca gcatttcagg ttgtttttct cactgcaggt catttcatgg 350

 gcaacaacac agtgctggat gttttgcggc gtgaaggcta tgaggtagaa 400

 cacgcccctg ctggacgacc catccacaaa gggaagagta aaaagacctc 450

 cacacggccc actctgtcca ccatctttgc tccaaaagtc cctaccctgg 500

 aagtaccggc accagaagcc gtatcctcag ggcactcaac gctgcctccc 550

 cttgtgtccc ggcctggaag tgccgacacg cccagtgagg ccgaacagag 600

 gttccggaag aagcggaggc ggtcacagcg gaggccgcga ctccggcaat 650

 tcagcgatct gtgggtccgc ctggaggaga gtgacatagt cccgcaactc 700

 caggtccctg tcctggacag gcacatctcc actgaactgc ggctccctcg 750

 ccgtgggcat tcccaccaca gccagatggt ggccagcagt gcctgcctgt 800

 ctctctggac tcctgtgttc tgggtgctgg tgctggcttt ccaaacagag 850

 acacccctcc tgtaacgact ggaagcacca ggctaagaac ctgacccctc 900

 ggacttgaag aatggccatt cctgtactcc acattctggt ctagccttgt 950

 tgggcccaat ccagaagaga ctgctcttga aaaagcggcc cagtgttgat 1000

 tcttctcttt ccaaggaatg tgactttggg ttatccaact ttgggggcag 1050

 gtgtacagtt ttgtaacata gtgagttgtg tgaaaataaa ttataaatga 1100

 gttgtatgaa aataaatac 1119

<210> 4579
<211> 172
<212> PRT
<213> Homo sapien

<400> 4579
 Met Gly Asn Asn Thr Val Leu Asp Val Leu Arg Arg Glu Gly Tyr
   1               5                  10                  15

 Glu Val Glu His Ala Pro Ala Gly Arg Pro Ile His Lys Gly Lys
                  20                  25                  30

 Ser Lys Lys Thr Ser Thr Arg Pro Thr Leu Ser Thr Ile Phe Ala
                  35                  40                  45

 Pro Lys Val Pro Thr Leu Glu Val Pro Ala Pro Glu Ala Val Ser
                  50                  55                  60

 Ser Gly His Ser Thr Leu Pro Pro Leu Val Ser Arg Pro Gly Ser
                  65                  70                  75

 Ala Asp Thr Pro Ser Glu Ala Glu Gln Arg Phe Arg Lys Lys Arg
                  80                  85                  90

 Arg Arg Ser Gln Arg Arg Pro Arg Leu Arg Gln Phe Ser Asp Leu
                  95                 100                 105

 Trp Val Arg Leu Glu Glu Ser Asp Ile Val Pro Gln Leu Gln Val
                 110                 115                 120

 Pro Val Leu Asp Arg His Ile Ser Thr Glu Leu Arg Leu Pro Arg
                 125                 130                 135

 Arg Gly His Ser His His Ser Gln Met Val Ala Ser Ser Ala Cys
                 140                 145                 150

 Leu Ser Leu Trp Thr Pro Val Phe Trp Val Leu Val Leu Ala Phe
                 155                 160                 165

 Gln Thr Glu Thr Pro Leu Leu
                 170

<210> 4580
<211> 1182
<212> DNA
<213> Homo sapien

<400> 4580
 gacccacgcg tccggttcta tgtactctct aaaatgttat cgttttcatt 50

 tgtctactaa ttttcgagca tttgttacta ctgagtttct taatatctga 100

 ctggcctccg cccacgggct ctgcagagca taaatactca ggctgatggt 150

 agtgcagaga ctctccctcc ttgatcagcg caaacgttgg tctgaggctt 200

 gagggatgga gcaacatttt cttggctgtg tgaagcgggc ttgggattcc 250

 gcagaggtgg cgccagagcc ccagcctcca cctattgtga gttcagaaga 300

 tcgtgggccg tggcctcttc ctttgtatcc agtactagga gagtactcac 350

 tggacagctg tgatttggga ctgctttcca gcccttgctg gcggctgccc 400

 ggagtctact ggcaaaacgg actctctcct ggagtccaga gcaccttgga 450

 accaagtaca gcgaagccca ctgagttcag ttggccgggg acacagaagc 500

 agcaagaggc acccgtagaa gaggtggggc aggcagagga acccgacaga 550

 ctcaggctcc agcagcttcc ctggagcagt cctctccatc cctgggacag 600

 acagcaggac accgaggtct gtgacagcgg gtgccttttg gaacgccgcc 650

 atcctcctgc cctccagccg tggcgccacc tcccgggttt ctcagactgc 700

 ctggagtgga ttcttcgcgt tggttttgcc gcgttctctg tactctgggc 750

 gtgctgttca cggatctgtg gagctaagca gccttagata gcagcagaag 800

 gctttttgga ttctcctcct tgaaaagatt ctcagttacc aaacgtctcc 850

 acctagaaaa taaaaataca ttaagatgtg ctttcattgc tggttgtcag 900

 tttttaaatt ctctttttcc cttatgtttc tttcttgttt cgcgtcgctt 950

 attactttca gtttccttgt attttaaata ttggtatttc attaaatatt 1000

 tcattcgtat ctgttttcac tttgagaaat ctattttacg attgtagaat 1050

 tcttagagtt tttggcaaat ttaaaatttg tttttttcca ttgtatttta 1100

 aaatcttatt cctactattt ttctaattat tgctttttaa atgtattgtt 1150

 tgtttacatt taattttaaa aaaaaaaaaa aa 1182

<210> 4581
<211> 193
<212> PRT
<213> Homo sapien

<400> 4581
 Met Glu Gln His Phe Leu Gly Cys Val Lys Arg Ala Trp Asp Ser
   1               5                  10                  15

 Ala Glu Val Ala Pro Glu Pro Gln Pro Pro Pro Ile Val Ser Ser
                  20                  25                  30

 Glu Asp Arg Gly Pro Trp Pro Leu Pro Leu Tyr Pro Val Leu Gly
                  35                  40                  45

 Glu Tyr Ser Leu Asp Ser Cys Asp Leu Gly Leu Leu Ser Ser Pro
                  50                  55                  60

 Cys Trp Arg Leu Pro Gly Val Tyr Trp Gln Asn Gly Leu Ser Pro
                  65                  70                  75

 Gly Val Gln Ser Thr Leu Glu Pro Ser Thr Ala Lys Pro Thr Glu
                  80                  85                  90

 Phe Ser Trp Pro Gly Thr Gln Lys Gln Gln Glu Ala Pro Val Glu
                  95                 100                 105

 Glu Val Gly Gln Ala Glu Glu Pro Asp Arg Leu Arg Leu Gln Gln
                 110                 115                 120

 Leu Pro Trp Ser Ser Pro Leu His Pro Trp Asp Arg Gln Gln Asp
                 125                 130                 135

 Thr Glu Val Cys Asp Ser Gly Cys Leu Leu Glu Arg Arg His Pro
                 140                 145                 150

 Pro Ala Leu Gln Pro Trp Arg His Leu Pro Gly Phe Ser Asp Cys
                 155                 160                 165

 Leu Glu Trp Ile Leu Arg Val Gly Phe Ala Ala Phe Ser Val Leu
                 170                 175                 180

 Trp Ala Cys Cys Ser Arg Ile Cys Gly Ala Lys Gln Pro
                 185                 190

<210> 4582
<211> 2206
<212> DNA
<213> Homo sapien

<400> 4582
 ttttcaacaa agaaccaatt tattaatata atgtacaaaa atagttggtt 50

 cattttctga attcagtctt tgaaataaaa ctccttgttt tggccgtgtt 100

 tctgaatgta ttggtgattc acccccaagc taatttttta aagtcatttt 150

 tgaagttggg aagtctcatg agagatgttg aagtatgtat ttaatcaaga 200

 gtcatgattt caaactagtt ttacatatta agcagttagt gttctaattt 250

 aatgggtaaa tgtgtgtttg gataaatatc tgaaaatttt atccttaagt 300

 atatataatt atttgcctct tatatgtctt aaagctattt aaacaaggtg 350

 ttaaatgagc caaaacaatt aagtaattag aacagtacat ttttatcaga 400

 gtgtctgtca tatgcaatga atgtatgtaa tactaaaaaa tcatgactac 450

 ttttatcaaa gaaaaaccac acattaatcc tattaatcat gaaagcgtag 500

 cattgtaaat taaaggtttt ctttgaggct cttgaaagtg atcccattgc 550

 tttcctgttt taaaaatatt ttatgctctt tatttccact tctgtgaatg 600

 tgatatttct attttgtgat tatgttactg aataaacaaa cttgctacat 650

 aaaattctta gcaattaaaa aaattctgat tctgccattt tgtctcaaat 700

 gtaatatacc cttttaatat catatgttta catatttatg aatgattaat 750

 catttttgtt tgcattaaac tttatgaaat gtcagaaatg attttactct 800

 aatgaaactc aaattttgcc caaagtagca atattcttaa agatgttgaa 850

 ttttgactgg ttgaatttta tatagtaaca cacaagtcgt gatcatcaat 900

 attattgcag accaggactc tgcttatatg ccttgctaac aaagatttct 950

 ttcacagagg cttttctcct ctcaagactt aaagtaagaa ttacatttta 1000

 ttaagtcagt taaatgcacc atggcttcat atagtaatat aaaaaaactc 1050

 tttgaagaga gaaatattat atcctaaaac ctctaaacca caaacattca 1100

 attgaaagag ttctgttgaa ggataatgac atactgactg cttacagacc 1150

 aagttgcttg cattttgtat gtttagccct cctttgccac tgcttttaga 1200

 gccttggaag gctaagtgtg atagtaatgc tagctctaat gcatatttaa 1250

 aggagactgc ctcgctttta gaagacatct ggtctgctct ctgcatgagg 1300

 cacagcagta aagctctttg attcccagaa tcaagaactc tccccttcag 1350

 actattaccg aatgcaaggt ggttaattga aggccactaa ttgatgctca 1400

 aatagaagga tattgactat attggaacag atggagtctc tactacaaaa 1450

 gtctttgggt atttgtttct tacatagaaa atgctaacat gaatagaaag 1500

 atactggtgc aagaccattc ccgggaaagt agacatactt acattttttt 1550

 ccttttctgc tcatttgaat gaactcaatt ttatgttaaa ttgttatatc 1600

 agagtgacaa ataagtgcta tggcttgata gaagtgaagc tcttcacata 1650

 tattcaaaat acatatcaca aactttggta aataggatag taatctgaag 1700

 aacttttgcc ctttttaccc catttactgt aactcttgtt tctaggtaat 1750

 cgttctctct caacaaactt ctcaagcgtc tgtgtaacaa gccacatgtt 1800

 ctaacaaatt gtctccatcg cacttcaaca gccaggtccc tattttttat 1850

 aacgtattaa ccttattatt ttcttattat tttaaaagaa tctatgcaca 1900

 ttagcaaaat ttaaaagata gagaaaaata taaacagaaa aaattatgtt 1950

 tacttctacc accctaaatc aactattatc aattttatac atattttact 2000

 ccatcttttt tcaaagtttc ttacattttc caatgtcatt aaaattctct 2050

 gtgaatgtaa attttaaaaa ctgtacctac tgttttttgg aaatctgtaa 2100

 caagctatgt gtaatcattc ttctaatatt aaacatattg tgtccaagaa 2150

 aaatctatgt cggtgcggag aaagagtaat gaaatggcag gaattcgata 2200

 tccagc 2206

<210> 4583
<211> 19
<212> PRT
<213> Homo sapien

<400> 4583
 Phe Ser Thr Lys Asn Gln Phe Ile Asn Ile Met Tyr Lys Asn Ser
   1               5                  10                  15

 Trp Phe Ile Phe


<210> 4584
<211> 2742
<212> DNA
<213> Homo sapien

<400> 4584
 aggttactat agtgtctgct cctacccctg ggacaagatc ccctaatgag 50

 ctggcaggtg ggcgtggggg gcacaggtac agcttggctt ctcagctttg 100

 ctcccctatc ctctgctttg ccatgaatct ctcatccagc cccgcaggga 150

 tctgcctggc cagcagtgag cctgagcccc tttcatcctg ggacctgccg 200

 accacggctc acatcctcct gggtgaagaa tgtcaccttg cttcctatct 250

 gcctctttcg tggttggctg gggaggggga ccggggggtg gggtgaggtt 300

 aacctcattg ttgtcttata tggtcattta aatctcccag ggcttcctcc 350

 aagggccaaa aataatccgg agacacagca gctgtgtcca gcacacagag 400

 gacccggcca tctgctttgg ttcagagccc tgtgtctgtc agtcagtctc 450

 tccctggctc tccctccatc ctcattcctg cctgaagcca tgacccgctt 500

 ctcctatgca gagtactttt ccctctttca ctcctgctct gcaccctcca 550

 ggtccactgc acctcctgag agttcgccgg cccgggcccc aatgggcttg 600

 ttccaagggg tcatgcagaa atacagcagc agcttgttca agacctccca 650

 gctggcgcct gcggacccct tgataaaggc catcaaggat ggcgatgaag 700

 aggccttgaa gaccatgatc aaggaaggga agaatctcgc agagcccaac 750

 aaggagggct ggctgccgct gcacgaggcc gcatactatg gccaggtggg 800

 ctgcctgaaa gtcctgcagc gagcgtaccc agggaccatc gaccagcgca 850

 ccctgcagga ggaaacagcc gtttacttgg caacgtgcag gggccacctg 900

 gactgtctcc tgtcactgct ccaagcaggg gcagagccgg acatctccaa 950

 caaatcccga gagacaccgc tctacaaagc ctgcgagcgc aagaacgcgg 1000

 aggccgtgaa gattctggtg cagcacaacg cagacaccaa ccaccgctgc 1050

 aaccgcggct ggaccgctct gcacgagtct gtgtctcgca atgacctgga 1100

 ggtcatgcag atcctggtga gcggaggagc caaggtggaa tccaagaacg 1150

 cctacggcat cacccccttg ttcgtggccg cccagagtgg acagttggag 1200

 gccttgaggt tcttagccaa gtacggtgct gacatcaaca cgcaggccag 1250

 cgacaacgcg tctgccctct acgaggcctg caagaatgag catgaggagg 1300

 tggtggagtt tctgctgtca cagggtgccg acgccaacaa gaccaacaag 1350

 gacggcttgc tcccgctgca catcgcctcc aagaagggca actacaggat 1400

 cgtgcagatg ctgctgccgg tgaccagccg cacgcgcata cgccgtagcg 1450

 gcgtcagtcc gctgcacctg gcggccgagc gcaaccacga cgaggtgctg 1500

 gaggcgctgc tgagcgcgcg cttcgacgtg aacacgccgc tggcgcccga 1550

 gcgcgcgcgc ctctacgaag accggcgcag ctccgcgctg tacttcgcgg 1600

 tggtcaacaa caacgtgtac gccaccgagc tgctgctgca acacggcgcc 1650

 gaccccaacc gcgacgtcat cagccccttg ctcgtggcca tccgccacgg 1700

 ctgcctgcgc acaatgcagc tgctgctgga ccacggcgcg aacatcgacg 1750

 cctatatcgc cacgcacccc accgccttcc ccgccaccat catgttcgcc 1800

 atgaagtgcc tgtcgctgct caagttcctc atggacctgg gctgcgacgg 1850

 cgagccctgc ttctcatgcc tctacggcaa cggcccgcac ccgccggccc 1900

 cgcagccctc cagcaggttc aacgacgcgc ccgcggccga caaggagccc 1950

 agcgtggtgc agttctgtga gttcgtatct gccccagagg tgagccgctg 2000

 ggcggggccc atcatcgatg tcctcctgga ctacgtgggc aacgtgcagc 2050

 tctgctcgcg gctgaaggaa cacatcgaca gctttgagga ctgggccgtc 2100

 atcaaggaga aggcagaacc tccaagacct ctggctcacc tttgccgact 2150

 gcgggttcga aaggccattg ggaaataccg tataaaactc ctagacacct 2200

 tgccgctccc aggcaggctg attagatacc tgaaatacga gaacacccag 2250

 taactggggc cacggggaga gaggagtagc ccctcagact cttcttacta 2300

 agtctcagga cgtcggtgtt cccaactcca aggggacctg gtgacagacg 2350

 aggctgcagg ctgcctccct ctcagcctgg acagctacca ggatctcact 2400

 gggtctcagg gcccagagct ttggccagag cagagaacag aatgtgtcaa 2450

 ggagaagaat catttgttta caaactgatg agcagatccc agaccttctc 2500

 taccttcagg aatggcagaa acctctattc ctggggccag ggcagagctt 2550

 gaggtgttct ggggaaggtg gtgctcagag ccttccctgt gcccctccac 2600

 ttgttctgga aaactcacca cttgacttca gagctttctc tccaaagact 2650

 aagatgaaga cgtggcccaa ggtagggggt agggggagcc tgggtcttgg 2700

 agggctttgt taagtattaa tataataaat gttacacatg tg 2742

<210> 4585
<211> 587
<212> PRT
<213> Homo sapien

<400> 4585
 Met Thr Arg Phe Ser Tyr Ala Glu Tyr Phe Ser Leu Phe His Ser
   1               5                  10                  15

 Cys Ser Ala Pro Ser Arg Ser Thr Ala Pro Pro Glu Ser Ser Pro
                  20                  25                  30

 Ala Arg Ala Pro Met Gly Leu Phe Gln Gly Val Met Gln Lys Tyr
                  35                  40                  45

 Ser Ser Ser Leu Phe Lys Thr Ser Gln Leu Ala Pro Ala Asp Pro
                  50                  55                  60

 Leu Ile Lys Ala Ile Lys Asp Gly Asp Glu Glu Ala Leu Lys Thr
                  65                  70                  75

 Met Ile Lys Glu Gly Lys Asn Leu Ala Glu Pro Asn Lys Glu Gly
                  80                  85                  90

 Trp Leu Pro Leu His Glu Ala Ala Tyr Tyr Gly Gln Val Gly Cys
                  95                 100                 105

 Leu Lys Val Leu Gln Arg Ala Tyr Pro Gly Thr Ile Asp Gln Arg
                 110                 115                 120

 Thr Leu Gln Glu Glu Thr Ala Val Tyr Leu Ala Thr Cys Arg Gly
                 125                 130                 135

 His Leu Asp Cys Leu Leu Ser Leu Leu Gln Ala Gly Ala Glu Pro
                 140                 145                 150

 Asp Ile Ser Asn Lys Ser Arg Glu Thr Pro Leu Tyr Lys Ala Cys
                 155                 160                 165

 Glu Arg Lys Asn Ala Glu Ala Val Lys Ile Leu Val Gln His Asn
                 170                 175                 180

 Ala Asp Thr Asn His Arg Cys Asn Arg Gly Trp Thr Ala Leu His
                 185                 190                 195

 Glu Ser Val Ser Arg Asn Asp Leu Glu Val Met Gln Ile Leu Val
                 200                 205                 210

 Ser Gly Gly Ala Lys Val Glu Ser Lys Asn Ala Tyr Gly Ile Thr
                 215                 220                 225

 Pro Leu Phe Val Ala Ala Gln Ser Gly Gln Leu Glu Ala Leu Arg
                 230                 235                 240

 Phe Leu Ala Lys Tyr Gly Ala Asp Ile Asn Thr Gln Ala Ser Asp
                 245                 250                 255

 Asn Ala Ser Ala Leu Tyr Glu Ala Cys Lys Asn Glu His Glu Glu
                 260                 265                 270

 Val Val Glu Phe Leu Leu Ser Gln Gly Ala Asp Ala Asn Lys Thr
                 275                 280                 285

 Asn Lys Asp Gly Leu Leu Pro Leu His Ile Ala Ser Lys Lys Gly
                 290                 295                 300

 Asn Tyr Arg Ile Val Gln Met Leu Leu Pro Val Thr Ser Arg Thr
                 305                 310                 315

 Arg Ile Arg Arg Ser Gly Val Ser Pro Leu His Leu Ala Ala Glu
                 320                 325                 330

 Arg Asn His Asp Glu Val Leu Glu Ala Leu Leu Ser Ala Arg Phe
                 335                 340                 345

 Asp Val Asn Thr Pro Leu Ala Pro Glu Arg Ala Arg Leu Tyr Glu
                 350                 355                 360

 Asp Arg Arg Ser Ser Ala Leu Tyr Phe Ala Val Val Asn Asn Asn
                 365                 370                 375

 Val Tyr Ala Thr Glu Leu Leu Leu Gln His Gly Ala Asp Pro Asn
                 380                 385                 390

 Arg Asp Val Ile Ser Pro Leu Leu Val Ala Ile Arg His Gly Cys
                 395                 400                 405

 Leu Arg Thr Met Gln Leu Leu Leu Asp His Gly Ala Asn Ile Asp
                 410                 415                 420

 Ala Tyr Ile Ala Thr His Pro Thr Ala Phe Pro Ala Thr Ile Met
                 425                 430                 435

 Phe Ala Met Lys Cys Leu Ser Leu Leu Lys Phe Leu Met Asp Leu
                 440                 445                 450

 Gly Cys Asp Gly Glu Pro Cys Phe Ser Cys Leu Tyr Gly Asn Gly
                 455                 460                 465

 Pro His Pro Pro Ala Pro Gln Pro Ser Ser Arg Phe Asn Asp Ala
                 470                 475                 480

 Pro Ala Ala Asp Lys Glu Pro Ser Val Val Gln Phe Cys Glu Phe
                 485                 490                 495

 Val Ser Ala Pro Glu Val Ser Arg Trp Ala Gly Pro Ile Ile Asp
                 500                 505                 510

 Val Leu Leu Asp Tyr Val Gly Asn Val Gln Leu Cys Ser Arg Leu
                 515                 520                 525

 Lys Glu His Ile Asp Ser Phe Glu Asp Trp Ala Val Ile Lys Glu
                 530                 535                 540

 Lys Ala Glu Pro Pro Arg Pro Leu Ala His Leu Cys Arg Leu Arg
                 545                 550                 555

 Val Arg Lys Ala Ile Gly Lys Tyr Arg Ile Lys Leu Leu Asp Thr
                 560                 565                 570

 Leu Pro Leu Pro Gly Arg Leu Ile Arg Tyr Leu Lys Tyr Glu Asn
                 575                 580                 585

 Thr Gln


<210> 4586
<211> 1027
<212> DNA
<213> Homo sapien

<400> 4586
 gaatctctcg cgggcagcag ggcgcgcgct gcacgcacag tactaggtca 50

 ggtggtgctc ccgggtgagg agctgctcct gccggaacag gaggacgcgg 100

 aaggccctgg gggtgcagtg gagcgaccgt tgagcctgaa tgctagagcg 150

 tgctcgcggg tgcgcgtttg tatgcggtcc gggccttcga cgctgtgggg 200

 accgcctgct ggtcaccaag tgcggccgcc tccgtcacaa ggagcccggc 250

 agtggaggcg gcggcggtgt ttactgggtg gactctcagc agaagcggta 300

 tgttccagta aaaggagacc atgtgattgg catagtgaca gctaaatctg 350

 gagatatatt caaagttgat gttggaggga gtgagccagc ttctttgtct 400

 tacttgtcat ttgaaggtgc aactaaaaga aacagaccaa atgtgcaggt 450

 tggagatctc atctatggcc agtttgtggt tgctaataaa gacatggaac 500

 cagagatggt ctgtattgac agctgtggac gagccaatgg aatgggtgtc 550

 attggacagg atggtctgct ttttaaagtg actctgggct taattagaaa 600

 gctattagct ccagattgtg aaatcataca ggaagtggga aaactctatc 650

 cactggagat agtatttgga atgaatggaa gaatatgggt taaggcaaaa 700

 accatccagc agactttaat tttggcaaac attttagaag cttgtgaaca 750

 catgacgtca gatcaaagaa aacagatctt ctccagattg gcagaaagtt 800

 gatataggtg gactttttta caggtcagtt gaggcaaaaa actatgggtt 850

 ttttcaggtg aacctccccc atttaaatac tcagaagata aggtgtgaat 900

 gtatgtatta ttagagtccg aaagtatttt tataagttac tggttttcac 950

 ccacgctttt gtgggagaga aaatcattgc aaaatcattt tttttgttcg 1000

 gtacaataaa gtttactaaa aaacaaa 1027

<210> 4587
<211> 220
<212> PRT
<213> Homo sapien

<400> 4587
 Met Leu Glu Arg Ala Arg Gly Cys Ala Phe Val Cys Gly Pro Gly
   1               5                  10                  15

 Leu Arg Arg Cys Gly Asp Arg Leu Leu Val Thr Lys Cys Gly Arg
                  20                  25                  30

 Leu Arg His Lys Glu Pro Gly Ser Gly Gly Gly Gly Gly Val Tyr
                  35                  40                  45

 Trp Val Asp Ser Gln Gln Lys Arg Tyr Val Pro Val Lys Gly Asp
                  50                  55                  60

 His Val Ile Gly Ile Val Thr Ala Lys Ser Gly Asp Ile Phe Lys
                  65                  70                  75

 Val Asp Val Gly Gly Ser Glu Pro Ala Ser Leu Ser Tyr Leu Ser
                  80                  85                  90

 Phe Glu Gly Ala Thr Lys Arg Asn Arg Pro Asn Val Gln Val Gly
                  95                 100                 105

 Asp Leu Ile Tyr Gly Gln Phe Val Val Ala Asn Lys Asp Met Glu
                 110                 115                 120

 Pro Glu Met Val Cys Ile Asp Ser Cys Gly Arg Ala Asn Gly Met
                 125                 130                 135

 Gly Val Ile Gly Gln Asp Gly Leu Leu Phe Lys Val Thr Leu Gly
                 140                 145                 150

 Leu Ile Arg Lys Leu Leu Ala Pro Asp Cys Glu Ile Ile Gln Glu
                 155                 160                 165

 Val Gly Lys Leu Tyr Pro Leu Glu Ile Val Phe Gly Met Asn Gly
                 170                 175                 180

 Arg Ile Trp Val Lys Ala Lys Thr Ile Gln Gln Thr Leu Ile Leu
                 185                 190                 195

 Ala Asn Ile Leu Glu Ala Cys Glu His Met Thr Ser Asp Gln Arg
                 200                 205                 210

 Lys Gln Ile Phe Ser Arg Leu Ala Glu Ser
                 215                 220

<210> 4588
<211> 2122
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 780-1076
<223> Unknown base

<400> 4588
 acagagaata cccttcagca tggccactct ggacccaaga ggaggaaaaa 50

 acggaagctt ttttaggaga aggaggactt gctggaatcc aagatgtgaa 100

 gaactcttgg tgactggctg gctggccagc gggcaccaca cctgcacttg 150

 agtgcctcgg gcttgcttat taataacgca cagaagaagc atcacttctc 200

 accatctcct ggcatgtatg gagcagggag caaggctatg ttcccgaaag 250

 ccctgattag cttgtcttgc tctacgctcg acctcgaaca atacagcttg 300

 taagacctca gtcagtcctg gtacactggg gtaaatcagt gtggtggtgg 350

 aagaaaagcc gggaggccta tttttatagg aaaatagtac cattaaaggt 400

 gcaatgctgt cattttggac aaaaggaaag aaatttggaa gagctgggat 450

 tattggcaaa aacttgctga ggggtgaatc tttagagcta atcactgcag 500

 aatcagagtt gcagcaatat gattgcaagc aagtctgaat gcatagtttt 550

 actttaattc ggcttgacaa tttgaatagg taaccccctc gggactgact 600

 gaatcgttat gcatgtgtca atcaatggga ggtgtgcatt ctctagaagt 650

 agttttaggc tgtttggttt ggttttggtt ttgtttttta aatgcagcct 700

 gttgaggcac tgtcatgtgg tgtgaaagat ttaaatgtag caacgctaaa 750

 gagtaataat ttggggataa gaagtggggn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1050

 nnnnnnnnnn nnnnnnnnnn nnnnnncaca ttccagagag tggtgatgac 1100

 ccaaatgttg aaccaattat gttttggtgg tggtgttctt agctgttgaa 1150

 tcctgaatgg tttataaagt gaactagctg gcttaatgca gccagcgttc 1200

 tgggcagcag aacatattca ttcttactgt aaattctatt tgctgcttcc 1250

 aaaggtgatg attttcaagc agacatgttc tatatggtct gtgttttagg 1300

 atctggtgcc cagcctctat cagagcttgc ctacctggca aagctgccta 1350

 cccttcaagt gggaaaatat aatccactgt ttaacaaggc tcaccctctc 1400

 caccctgtcc taacgacctt ttgtgaatgt gctgtgatat tttcttgctc 1450

 aatagcaagg tggtagctct gctttcattt taagaaagtg gaggctgagg 1500

 gcattgtatc aatactgttg caactccaag aagttttcct tgtaaaatta 1550

 aaggaaagat cttgttattg attaaccatt ttcttatgcc ttgctattga 1600

 catattcatg ctctttctac gtctagtggc tgaaaatgtt tgcatttgtt 1650

 catttgacta atggtgtgat ttttgtttct atattattag acctgtaatg 1700

 ttttaaaatg tattttatta aatttggact ggatgtatgt ctctagcaat 1750

 acgaggtact ttctaaacta ttaagggagg ggttgtatcc tcatgttgag 1800

 ataagatgat ggtcgtttaa attttgcaat tttttttggc ctgcagggat 1850

 attttgtgtt tatgtgtcca aaaaaggaat aaattggcat tcttgtgcca 1900

 aaagttgttt ttcctgtcaa ttgtctaata agtatgcagt acactgtaat 1950

 ggcaacatac atggttgctt tataaaaaca gtttcctcag tatgagaaat 2000

 tttacaaaga acagtggaaa aactttgtgt ttttaactct tgggtctccc 2050

 tatttttaaa aattgctatt tggtatacaa ttattatgtg tcaattaaaa 2100

 ctaaaataaa acttttaaaa aa 2122

<210> 4589
<211> 134
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 30-129
<223> unknown amino acid

<220>
<221> Unsure
<222> 780-1076
<223> Unknown amino acid

<400> 4589
 Met Gln Pro Val Glu Ala Leu Ser Cys Gly Val Lys Asp Leu Asn
   1               5                  10                  15

 Val Ala Thr Leu Lys Ser Asn Asn Leu Gly Ile Arg Ser Gly Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 110                 115                 120

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa His Ser Arg Glu Trp
                 125                 130

<210> 4590
<211> 1754
<212> DNA
<213> Homo sapien

<400> 4590
 tactgggttt ttatgagagg aaaatagaaa atgctcttct agaagagaga 50

 gaacaagagc acaaaataat ctggactcac aaaaattcag caagctccaa 100

 gaaaggggga tggagggaac gctggcaaaa atttaaatgc cattaggata 150

 tttagcaagt tattactgtt tggtaaaaat gcatcatcac cctgtgtgca 200

 aaatgcttgc aaagtagtct aaatgtcttt ggagatgggt gttttactgc 250

 ttttttccaa aaacaaattg tttattatgg ttgcagaaat gcagccatta 300

 cggtcacata aatttctaaa aagcctacca aaggttgcaa gcagtcttct 350

 gccactgggc aggccagcag ttcagaccca gcgaggttgc caggaacaaa 400

 tccaggaaat actgggaaga acaagacaag agaattacct aaaagagcaa 450

 acaattcaag taaatcctgt agctattacc acttaaaatc cgtagctcaa 500

 gattcctgtt tcaccacctt atacacttaa gcaattatac ttaagccttt 550

 ttttagtcct aagtgaagaa ctacatcaga atcaggataa gtattttgcc 600

 tgggaaattt ggctgcatat gaatggagaa gacatttaca tcctatgttc 650

 tggcactttc tgaaagatct aattaaacat gttgatgtgc caatttaatc 700

 aagatgagag atccctgctg gtgtcaccct ctagaacctg cacttggtgt 750

 tttgactttc cagaagaaaa aaatgcaact ttggttaggg ggcagtggtt 800

 ggatcacaca gttgtctttc gtttcctacc acagtaattc atatttaaat 850

 atgcttttag attagtgtgg atactattgc tgctgtgttg ctacctgacc 900

 tttttctggg gggggtacct cagaaatgag catttgaggg caagcgaaaa 950

 agccctcttc atcctccaga ggcaacaaag aggcagcaga aatggggaaa 1000

 gattgtgaga ggcagggctt gggtctagac ctggacttag gcaagatatg 1050

 ttgccctcaa ccctgagttt tcttatatgt aaaaagggaa ggttgggctg 1100

 gactagatga ggtcaagatt tgccattctg ggaggctgat attccagaga 1150

 atcaaaatta atcctaaacc aaagctttat ggctgctaca gagacatgtc 1200

 acatttctga gacttgtcac caagagtttg tccctcagac tttggcgctg 1250

 ttgaatgcaa agacaaggat ggccaccttc tggttcttgc ctgttgtcct 1300

 cagctgagag cagtctcggt aaaggtggca aagattctgt gacctcagac 1350

 tggggaccaa atgcttggga gtctgatggc cgggctgggc caccattctc 1400

 atagctctca ttctgtttgg agcaaccaaa ggatttgtgt gaagttattt 1450

 ggaaaaggac cttaactgag cagtaatctt ttttctgtat atttggaatg 1500

 tttttcattc tgacctgttc tgtcagtgat tctactgaaa aacaatttaa 1550

 tcaatataaa aatgttcaag ctatgcaaca ctgttattgt ctgttgacat 1600

 ttttattcta attgatttct gcaaatcttt tcttatttgt gtttgctttt 1650

 tcctttcatt tagaaatcaa ctcttttgga ggagagtgct ctctgctcat 1700

 ctccaccttc cctctggtca ggagcatgaa ctcccatctt ggccttgtcc 1750

 tggg 1754

<210> 4591
<211> 47
<212> PRT
<213> Homo sapien

<400> 4591
 Leu Gly Phe Tyr Glu Arg Lys Ile Glu Asn Ala Leu Leu Glu Glu
   1               5                  10                  15

 Arg Glu Gln Glu His Lys Ile Ile Trp Thr His Lys Asn Ser Ala
                  20                  25                  30

 Ser Ser Lys Lys Gly Gly Trp Arg Glu Arg Trp Gln Lys Phe Lys
                  35                  40                  45

 Cys His


<210> 4592
<211> 1857
<212> DNA
<213> Homo sapien

<400> 4592
 ggtccaaact gtgccacctt ccacccctgc gctgggagag cagacatcgc 50

 ccactcgggc tcacagtgcc atccgggtga ggacctccgt ggagagctct 100

 ctttgccaaa gaaaagcagt tgcattaggt ctgcgagcag gcagggtggc 150

 ctcttcctgg ctccccatcc accaaggaag cttcaagtcc ctgggacaca 200

 ggcactttcc cacacaggat ggagccgggc caccctcaca gctcctgccc 250

 tgcagacgct gagcttgtgg agggaggcag gcagcaggag caggcgatgc 300

 ccaaagcgtg gagaccagca ctgctctctc cccagtgaca ggtgcacgcc 350

 cagatcacgg atgtgtcggg aacagctgtg ctcctgctgc tcagcgtccg 400

 tcactccagg ctgggagcgg gtccccaagc ttctggctgg gcctatccgt 450

 ctccactctc agtgtggggg gtggggggcg ccaacagcac gcatttgctc 500

 tctgcacttc tcgtctgata atgggcagag ggtccttctg cagccccaaa 550

 acatccctag gcaggagccc tggggcccca agcagccagg gaggtgagca 600

 ccaaggacct cccagagagc gtcaccttcc gtcgagggag gcccagcctg 650

 ggggcggtgt ctgagacttg gaatcaacgc ttccgttggt ggcagtaaat 700

 cctgtcccta accctgcagt atagctgtgc cgtgtacagg agggtgttgt 750

 ctgacgccag acacctggac tacagatcgc agcctgattc ctggtcattg 800

 ctccactgaa ccccagaccc cagcctcgtt ctgggccctc atcccctaga 850

 tccagggacc ccagccccat ttcagccctt gggcccttgt aggatgcgag 900

 gccctgggcc ccagccccca gcccatccgt gttccaggca ctggggggct 950

 gaggtcctct gagaagggac acagggcctg gggggctctc tcagcccatc 1000

 agcaggagag gactgactcc agaaaaatca gcgtttgtac ccactcaggc 1050

 tgccaagacc tgtgtccgtc cttccaagct caaccttcag agttcatgag 1100

 gccccttgcc cagaatgtcc acagagttca tgaggcccct tgaatgtcca 1150

 cagagttcat gaggctcctt gcccggaatg tccacatttg aaacctccca 1200

 acaccgagcc ccatttcaag tataaccagg agggaaaatg gtgcttgaaa 1250

 taagcatgcc acaaaggaaa acctgctttc tcgaaatggg ccctggccgc 1300

 ccaggccctg acctccccgg ccaggatgga acgttccaga gacccattag 1350

 tgccaaaggc aaatgaaaac acaccctgtg aaaatgtctc tgctgtctcc 1400

 caagtattta tttttctgag cgtggggaag gaaggcttaa ttaagatgcc 1450

 ctcaggcggg tacgaggggc aaagtgggag cagggagcgt gcttcctctg 1500

 tggccttggt tcagacaaca gccttcagca aagctttgct ctagaggctc 1550

 ataggaaggg acagagggca caggcccagc tcagcctttc ccctgccttt 1600

 cttggggcct gggcatggac agcaccgcct ggcgacacac aacggtgggc 1650

 tctgaggctg tttgttacgc agcattaatg tggccgtcgg tgaccgctac 1700

 acggtgactg ataactgcac tgtgggtaga gctcagcccg cagggctctg 1750

 gtttgtgacc tctgggccag gcaactctca aggcttcttc cagtgcagaa 1800

 tatgattccc gcagcagcgc ccagcgagaa ctgcgaagga ggcaggctcc 1850

 gggcacc 1857

<210> 4593
<211> 198
<212> PRT
<213> Homo sapien

<400> 4593
 Gly Pro Asn Cys Ala Thr Phe His Pro Cys Ala Gly Arg Ala Asp
   1               5                  10                  15

 Ile Ala His Ser Gly Ser Gln Cys His Pro Gly Glu Asp Leu Arg
                  20                  25                  30

 Gly Glu Leu Ser Leu Pro Lys Lys Ser Ser Cys Ile Arg Ser Ala
                  35                  40                  45

 Ser Arg Gln Gly Gly Leu Phe Leu Ala Pro His Pro Pro Arg Lys
                  50                  55                  60

 Leu Gln Val Pro Gly Thr Gln Ala Leu Ser His Thr Gly Trp Ser
                  65                  70                  75

 Arg Ala Thr Leu Thr Ala Pro Ala Leu Gln Thr Leu Ser Leu Trp
                  80                  85                  90

 Arg Glu Ala Gly Ser Arg Ser Arg Arg Cys Pro Lys Arg Gly Asp
                  95                 100                 105

 Gln His Cys Ser Leu Pro Ser Asp Arg Cys Thr Pro Arg Ser Arg
                 110                 115                 120

 Met Cys Arg Glu Gln Leu Cys Ser Cys Cys Ser Ala Ser Val Thr
                 125                 130                 135

 Pro Gly Trp Glu Arg Val Pro Lys Leu Leu Ala Gly Pro Ile Arg
                 140                 145                 150

 Leu His Ser Gln Cys Gly Gly Trp Gly Ala Pro Thr Ala Arg Ile
                 155                 160                 165

 Cys Ser Leu His Phe Ser Ser Asp Asn Gly Gln Arg Val Leu Leu
                 170                 175                 180

 Gln Pro Gln Asn Ile Pro Arg Gln Glu Pro Trp Gly Pro Lys Gln
                 185                 190                 195

 Pro Gly Arg


<210> 4594
<211> 1014
<212> DNA
<213> Homo sapien

<400> 4594
 agcggaaggg gcctttcgga acgatttgga acgaaaggaa gtggaagaaa 50

 cgcggaacca tggccgctgt ggttgctgtt tgcggtggtc tagggaggaa 100

 gaagttgaca cacttggtaa cggctgctgt cagccttaca catcccggga 150

 ctcacacggt gctttggaga agaggttgtt cacaacaggt atccagcaat 200

 gaggacctgc ccatttcaat ggaaaatcct tataaagaac ctcttaagaa 250

 atgtatcttg tgtggaaagc atgtagatta taagaatgta cagcttttgt 300

 cccagtttgt ttctccattt actggatgca tttatggaag gcacattaca 350

 ggtctttgtg ggaagaaaca gaaagaaatc acaaaagcaa ttaagagagc 400

 tcaaataatg gggtttatgc cagttacata caaggatcct gcatatctca 450

 aggaccctaa agtttgtaac atcagatatc gggaataaat tctatcacgt 500

 taccactaat aaacttattt tacagtaagt ggttgtatga tgccaatact 550

 gactcaaacc aacctttgga tagaaaagtg tttgaggagt gaggtaaaga 600

 atgacacttc cccttcatac caatgtccat taagcagatt gcttatttaa 650

 aatgttaaca ctcatcacat tttatctatg ttgaataaaa gtggttctgt 700

 gtgattgtca tttatatctg atccccaaat agctcataca ataatccatt 750

 caatagaatg gaattaaaac tgttcagaat gattttccaa ctagcaaata 800

 taagtatgcc tggttaagat atcttccctt tgtagaaatg ttacattggg 850

 atggatagtg gtgctgtcac agaaggacaa aatattccta gacgagtcta 900

 tcctcaaacc agtagtgtct tttacatgaa gagatgattt acacctaata 950

 gacattgaat atgatagaca tacatgtata tatgtatcag ttctgagttc 1000

 cactggccta tccc 1014

<210> 4595
<211> 142
<212> PRT
<213> Homo sapien

<400> 4595
 Met Ala Ala Val Val Ala Val Cys Gly Gly Leu Gly Arg Lys Lys
   1               5                  10                  15

 Leu Thr His Leu Val Thr Ala Ala Val Ser Leu Thr His Pro Gly
                  20                  25                  30

 Thr His Thr Val Leu Trp Arg Arg Gly Cys Ser Gln Gln Val Ser
                  35                  40                  45

 Ser Asn Glu Asp Leu Pro Ile Ser Met Glu Asn Pro Tyr Lys Glu
                  50                  55                  60

 Pro Leu Lys Lys Cys Ile Leu Cys Gly Lys His Val Asp Tyr Lys
                  65                  70                  75

 Asn Val Gln Leu Leu Ser Gln Phe Val Ser Pro Phe Thr Gly Cys
                  80                  85                  90

 Ile Tyr Gly Arg His Ile Thr Gly Leu Cys Gly Lys Lys Gln Lys
                  95                 100                 105

 Glu Ile Thr Lys Ala Ile Lys Arg Ala Gln Ile Met Gly Phe Met
                 110                 115                 120

 Pro Val Thr Tyr Lys Asp Pro Ala Tyr Leu Lys Asp Pro Lys Val
                 125                 130                 135

 Cys Asn Ile Arg Tyr Arg Glu
                 140

<210> 4596
<211> 1150
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 540-593
<223> Unknown base

<400> 4596
 cgggcttcct gcatcttcca ccgcaaatga ttcttttgag aaaagcaccc 50

 ataatttgct acttgaggat tttattccct ggattctctg gatgctcatt 100

 gcatgaaaag tggaaaagtt tagatctatg gaaacagaac tgttgcctat 150

 atggaaaatc agtgccttgt ggcaatacag gtaagaacag tgttgctctt 200

 gaaaaagtgg acagtgggtg gtctgaatgt gtcctggtcc ctggagtggg 250

 tttttagatt gatgtggact cttcttagac ttgtaagtaa aaaagttgtt 300

 tcttccccta aaagggaact gtgcgcctta gacctggaat tgctgggaaa 350

 ctgaaacatt ctgtagactt acttgtttcc aactgtatcg cagcaagaag 400

 tctatgtgcc ccaggatcct ggattacctg aggaagaaga gatcaaggaa 450

 aaaaaaccca ccagtcaagg aaagtcaagt agcaagaagg aaatgtctaa 500

 aagagatggc aaggagaaaa aagacagagg agtgacgagn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntcaggaa 600

 aatgccagtg aagggaaggc ccctgcagaa gacgtcttta agaagcccct 650

 gcctcctact gtgaagaagg aagagagtcc ccctccacct aaagtggtaa 700

 acccactgat cggcctcttg ggtgaatatg gaggagacag tgactatgag 750

 gaggaagaag aggaggaaca gacccctccc ccacagcccc gcacagcaca 800

 gccccagaag cgagaggagc aaccaagaag gagaatgaag aagacaaact 850

 ccctgactgg aataaactgg cttgtctgct ttgcagaagg catgtttccc 900

 aataaagaag ttctgatcaa acaccagcag ctgtcagacc tgcacaagca 950

 aaacctggaa atccaccgga agataaaaca gtctgagcag gagctagcct 1000

 atctggaaag gagagaacga gagggaaaat tttaaagaaa gaggaaatga 1050

 tcccagggaa aagctccagt cttttgactc tccagaaagg aaacggatta 1100

 agtactccag ggaaactgac agtgatcgta aacttgttga taaagaagat 1150

<210> 4597
<211> 180
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 16-34
<223> unknown amino acid

<220>
<221> Unsure
<222> 540-593
<223> Unknown amino acid

<400> 4597
 Met Ser Lys Arg Asp Gly Lys Glu Lys Lys Asp Arg Gly Val Thr
   1               5                  10                  15

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Gln Glu Asn Ala Ser Glu Gly Lys Ala Pro Ala
                  35                  40                  45

 Glu Asp Val Phe Lys Lys Pro Leu Pro Pro Thr Val Lys Lys Glu
                  50                  55                  60

 Glu Ser Pro Pro Pro Pro Lys Val Val Asn Pro Leu Ile Gly Leu
                  65                  70                  75

 Leu Gly Glu Tyr Gly Gly Asp Ser Asp Tyr Glu Glu Glu Glu Glu
                  80                  85                  90

 Glu Glu Gln Thr Pro Pro Pro Gln Pro Arg Thr Ala Gln Pro Gln
                  95                 100                 105

 Lys Arg Glu Glu Gln Pro Arg Arg Arg Met Lys Lys Thr Asn Ser
                 110                 115                 120

 Leu Thr Gly Ile Asn Trp Leu Val Cys Phe Ala Glu Gly Met Phe
                 125                 130                 135

 Pro Asn Lys Glu Val Leu Ile Lys His Gln Gln Leu Ser Asp Leu
                 140                 145                 150

 His Lys Gln Asn Leu Glu Ile His Arg Lys Ile Lys Gln Ser Glu
                 155                 160                 165

 Gln Glu Leu Ala Tyr Leu Glu Arg Arg Glu Arg Glu Gly Lys Phe
                 170                 175                 180

<210> 4598
<211> 2153
<212> DNA
<213> Homo sapien

<400> 4598
 gggctctcta taatggaatg atgctccttt tcaatactta gagccactgt 50

 actcagttta ggagtaactg aaggtgtgga tgcatgttaa tgggaatcca 100

 atttttacta tttttatatt aataacagcg ttctgtagaa acagtctctc 150

 ccttctaaat aaaaactatg tgactgctgt tactagtgct attctatgcg 200

 aatatcctaa taataggatt caggaattct aatgaattgt ttcttaatta 250

 aggtgaacaa gtagactcct gatcaagagg agaacactgt gaatgtctca 300

 taatcaatag accttcattc tcttgtagaa aatgtggatt ttcaggaaaa 350

 gactgattat tttcatgaat aaattttctt atacaaattc cattttgttt 400

 gacataaaag accctgaatc ttaagatatt tgtaaatcag aatatttaag 450

 aatgtaaaat gaatccccaa atctagtttc ctccaaagca cttcttaatg 500

 taggaaatag tttttacaaa ccctatgtca gtactaatgt tcctgggtca 550

 aacccagtaa tattgttagt gtatgttgtt acaccttatt taagaggcag 600

 agtggttttg agcaagtcag ttaacgtgat ttgatgaaga aataaggaat 650

 tatatacatt tagacagaag aatattttat tttgaaaata ggatttcgtg 700

 caataatttt tcttgcataa cttagttcat ataaatatgt acatctgttt 750

 ttctggcaga tgccttaagg tcatgttttt cagtatttga gtaaatctgt 800

 atgtagcaat gttctcattg atttcagaaa aaaatatatt ctttatattg 850

 ttgccaggag aaatgttttt gtttatttaa aattattatg gatattgtgt 900

 tgttgtatca taactaactg cctcagcaac aataaatatg cagtaagaaa 950

 atcctgtacc ttagattgac aatactgtta ctttaaaaga aatatatacg 1000

 gtacaaattg ctgattctac atgtgtacat ttaacagata ctcagttctg 1050

 caccacctaa atcaaaatgg catttgtatg ctgatgatta catatgtgga 1100

 ttgtagtatc ctttgtgatg aatctttgat aagatttata aagggcattg 1150

 ccaatacttt ttgactgtgt aaattaagtt aattttttgt atgatgtaca 1200

 gtttgtttaa ccttagagct tctatagatt tctactttat tatacttgaa 1250

 tgaggcagaa aagcactgtg gaaaatctgt agctctggat gcaacatgca 1300

 gacataccaa aaaaataata ataaagcaag gtactgaaga gcaatgttaa 1350

 cagaatgctt tatatccaga atgctatgtt tttttcaagc cacattttag 1400

 ttgaatgaag taaagttatt caatctttta ttttaaaata ttggaaagtc 1450

 acaaatgatt acctctttga tatgatgaac ctataagtct attcatctct 1500

 gttatttcat ttctcaaatg tgagccttgt tgaggtccat tatcaaatct 1550

 acactttggt tgattatatg atgtttagga caaggcagaa tttaaaacct 1600

 gcatgtttag tgcatcacat gtcaagtcac catccttctg acagtgtaac 1650

 ttccataacg ttattttgag agccatttaa taatcatatt tgaaaaagtg 1700

 gatttcttga gtctgttgta gtttagtact tacagcagtg cctaaaacag 1750

 caactaatat gaactgcctg agtcctacaa cataaatgca taaagctttt 1800

 ttatgtaaaa gccacaggag gggttcaaaa ttgaactttt ccaaagttta 1850

 tttctcttgc gttagatgaa aaactattta aaaggactga aaaccctgag 1900

 ctttttgctc gtcttggtag cagatatctg taaaaaccta cccagaattg 1950

 tgattttact tcattgttct tgcatccttg aggctacagt ataaatcatc 2000

 tccaaacttg actactattg ggaagatgtg tataaaagca tcgctttggg 2050

 aattttttaa aaaatatgca aaaataaata ttgaataaaa tctacattac 2100

 cataaaacac ccaaaaatgc agttctaaaa taaaattggt cacaattaaa 2150

 ctt 2153

<210> 4599
<211> 12
<212> PRT
<213> Homo sapien

<400> 4599
 Ala Leu Tyr Asn Gly Met Met Leu Leu Phe Asn Thr
   1               5                  10

<210> 4600
<211> 402
<212> DNA
<213> Homo sapien

<400> 4600
 gcggccgcct actactacta aattagcggc cggtcgacgt ccgaggggga 50

 agaggtttgt taatacgttc gccatgtgct acgatcttgg gacgaactga 100

 gccacgagcg tggctttgag ggccgtccga acgctgcagg ccggccaggt 150

 ccctgggcgt ccaggcctgg cctacgcacc actttgtccc ttagcgttta 200

 aaggtttctt cccgaatctc aggccctcag ctacctgcag gtttcgtcgc 250

 gagccggctg caagttttga acctaagtaa acctcaatcc ggagggccta 300

 gcggtaaggt gggcgctgtg tctattgagg tgcttagcaa taaagaaagg 350

 tagtgagttg aaataaagac agtaaagtcg accggccgcg aatttagtag 400

 ta 402

<210> 4601
<211> 32
<212> PRT
<213> Homo sapien

<400> 4601
 Arg Pro Pro Thr Thr Thr Lys Leu Ala Ala Gly Arg Arg Pro Arg
   1               5                  10                  15

 Gly Lys Arg Phe Val Asn Thr Phe Ala Met Cys Tyr Asp Leu Gly
                  20                  25                  30

 Thr Asn


<210> 4602
<211> 1374
<212> DNA
<213> Homo sapien

<400> 4602
 cggctcgagc cgagttccgg gcgcgaggcg gccaccgtgg agagcagagc 50

 gcggcggctg gaagctgcta agtcagagcc gcgatgttcc ggattgaggg 100

 cctcgcgccg aagctggacc cggaggagat gaaacggaag atgcgcgagg 150

 atgtgatctc ctccatacgg aactttctca tctacgtggc cctcctgcga 200

 gtcactccat ttatcttaaa gaaattggac agcatatgaa gacaggacat 250

 cacatatgaa tgcacgatat gaagagcctg gttacagttt cgactcctct 300

 ctgcaagtga ataggcccag aaaggtgtaa gagactcttt gaatggacat 350

 aaaattctgc ttgttaagaa caagtttggc tctggtaact gaccttcaaa 400

 gctaaaatat aaaactattt gggaagtatg aaacgatgtc tcgtgatctg 450

 gtgtaccctt atccctgtga cgtttggcct ctgacaatac tggtataatt 500

 gtaaataatg tcaaactccg ttttctagca agtattaagg gagctgtgtc 550

 tgaaatggca ctgtcttgtc agtcatttct gtttaccttt ttcttctgcc 600

 cagagtgtat ttgtgaagag tctcttatat tatgttttgt ggaaatcagc 650

 acacaaccac aatgacattt aagcacagga tcattattag tctatgtttt 700

 taataaacat atcaattaag atcctgtgct taaatgtcat tgtggttgtg 750

 tgctgatttc cacaaaacat aatataagag actcttcaca aatacactct 800

 gggcagaaga aaaaggtaaa cagaaatgac tgacaagaca gtgccatttc 850

 agacacagct cccttaatac ttgctagaaa acggagtttg acattattta 900

 caattatacc agtattgtca gaggccaaac gtcacaggga taagggtaca 950

 ccagatcacg agacatcgtt tcatacttcc caaatagttt tatattttag 1000

 ctttgaaggt cagttaccag agccaaactt gttcttaaca agcagaattt 1050

 tatgtccatt caaagagtct cttacacctt tctgggccta ttcacttgca 1100

 gagaggagtc gaaactgtaa ccaggctctt catatcgtgc attcatatgt 1150

 gatgtcctgt cttcatatgc tgtccaattt ctttaagata aatggagtga 1200

 ctcgcaagag ggccacgtag atgagaaagt tccgtatgga ggagatcaca 1250

 tcctcgcgca tcttccgttt catctcctcc gggtccagct tcggcgcgag 1300

 gccctcaatc cggaacatcg cggctctgac ttagcagctt ccagccgccg 1350

 cgctctgctc tccacggtgg ccgc 1374

<210> 4603
<211> 74
<212> PRT
<213> Homo sapien

<400> 4603
 Met Ser Cys Leu His Met Leu Ser Asn Phe Phe Lys Asp Lys Trp
   1               5                  10                  15

 Ser Asp Ser Gln Glu Gly His Val Asp Glu Lys Val Pro Tyr Gly
                  20                  25                  30

 Gly Asp His Ile Leu Ala His Leu Pro Phe His Leu Leu Arg Val
                  35                  40                  45

 Gln Leu Arg Arg Glu Ala Leu Asn Pro Glu His Arg Gly Ser Asp
                  50                  55                  60

 Leu Ala Ala Ser Ser Arg Arg Ala Leu Leu Ser Thr Val Ala
                  65                  70

<210> 4604
<211> 1179
<212> DNA
<213> Homo sapien

<400> 4604
 ggcacgaggt gatgaagaag ccagttatct cagatttcga aatagtatat 50

 ggaaaaatga agaagagaaa gtggaaattt ttcatccttt gcgactagtt 100

 cgggatccac tgtcacctgc tgtaagacag aaagaaactg tgaaaaatga 150

 cctgcctgta aatgaagctg caattagaaa aatagctgcc cttgaaaatg 200

 agctgacttt tcttcgctct cagattgcag caattgtgga aatgcaggaa 250

 ctgaaaaata gtacaaattc tagttccttt ggcttgagtg acgagcgcat 300

 tagtttgggt cagctgtcat catcgcgggc tgcccatctg agtgtggacc 350

 cagatcagct tccaggttca gtgctttctc ctcctcctcc tccaccactt 400

 cctcctcagt tttcatctct ccagccaccg tgttttcctc ccgtacaacc 450

 aggatctaat aatatttgtg actcagataa tccagcaact gaaatgagca 500

 aacagaaccc ggctgctaat aagaccaatt atagtcatca ttcaaaaagc 550

 cagagaaata aagatattcc aaacatgttg gacgttctaa aggatatgaa 600

 taaggttaag cttcgtgcaa ttgagcggtc acctggcggt agacccattc 650

 ataagaggaa aagacagaat tcacattggg atccagtttc tttaatatct 700

 catgcactta aacagaaatt tgcatttcaa gaagatgatt cttttgagaa 750

 agagaataga tcttgggaat cttccccatt ttctagtcca gaaacttcaa 800

 ggtttggaca tcacatttca cagtcagaag gacagcgaac taaagaagaa 850

 atggtcaaca caaaagctgt tgaccaaggt atcagcaaca caagccttct 900

 aaactcaagg atttaaactc aacttaaggt tgagctttaa acttccaaaa 950

 cttcttcctg gatgataaat tattcttaga aactgatttg gactgttaaa 1000

 ggctaaaagt agatgtattt aaagactctt cttgacacat tttgcctaca 1050

 cttgctatgt aaatatgtat gcctgtcatt tttgtttcct ttgttccttt 1100

 ttacgtttat actctgttct tctgtacata gagcttaaaa taaacattct 1150

 ttttgaactt gaaaaaaaaa aaaaaaaaa 1179

<210> 4605
<211> 224
<212> PRT
<213> Homo sapien

<400> 4605
 Met Gln Glu Leu Lys Asn Ser Thr Asn Ser Ser Ser Phe Gly Leu
   1               5                  10                  15

 Ser Asp Glu Arg Ile Ser Leu Gly Gln Leu Ser Ser Ser Arg Ala
                  20                  25                  30

 Ala His Leu Ser Val Asp Pro Asp Gln Leu Pro Gly Ser Val Leu
                  35                  40                  45

 Ser Pro Pro Pro Pro Pro Pro Leu Pro Pro Gln Phe Ser Ser Leu
                  50                  55                  60

 Gln Pro Pro Cys Phe Pro Pro Val Gln Pro Gly Ser Asn Asn Ile
                  65                  70                  75

 Cys Asp Ser Asp Asn Pro Ala Thr Glu Met Ser Lys Gln Asn Pro
                  80                  85                  90

 Ala Ala Asn Lys Thr Asn Tyr Ser His His Ser Lys Ser Gln Arg
                  95                 100                 105

 Asn Lys Asp Ile Pro Asn Met Leu Asp Val Leu Lys Asp Met Asn
                 110                 115                 120

 Lys Val Lys Leu Arg Ala Ile Glu Arg Ser Pro Gly Gly Arg Pro
                 125                 130                 135

 Ile His Lys Arg Lys Arg Gln Asn Ser His Trp Asp Pro Val Ser
                 140                 145                 150

 Leu Ile Ser His Ala Leu Lys Gln Lys Phe Ala Phe Gln Glu Asp
                 155                 160                 165

 Asp Ser Phe Glu Lys Glu Asn Arg Ser Trp Glu Ser Ser Pro Phe
                 170                 175                 180

 Ser Ser Pro Glu Thr Ser Arg Phe Gly His His Ile Ser Gln Ser
                 185                 190                 195

 Glu Gly Gln Arg Thr Lys Glu Glu Met Val Asn Thr Lys Ala Val
                 200                 205                 210

 Asp Gln Gly Ile Ser Asn Thr Ser Leu Leu Asn Ser Arg Ile
                 215                 220

<210> 4606
<211> 1230
<212> DNA
<213> Homo sapien

<400> 4606
 gtaaaagcaa aagcaacagc tcaagcagcc tccttggaga aaacctgaaa 50

 attcaacttg ttcaagagaa ggtcttgtac gtgcctaagt tctagagcct 100

 cctgacgtga gcatggctga gagtgaggac cgctccctga ggatcgttct 150

 ggtagggaaa actggaagtg ggaaaagtgc aacagcgaac accatccttg 200

 gagaggaaat ctttgattct agaattgctg cccaagctgt taccaagaac 250

 tgtcaaaaag catcccggga atggcagggg agagaccttc ttgttgtaga 300

 cactccaggg ctctttgaca ccaaggagag cctggacacc acctgcaagg 350

 aaatcagccg ctgcatcatc tcctcctgcc cagggcccca tgctattgtc 400

 ctagttctgc tgctgggccg ctacacagag gaggagcaga aaaccgttgc 450

 attgatcaag gctgtctttg ggaagtcagc catgaagcac atggtcatct 500

 tgttcactcg caaagaagag ttggagggcc agagcttcca tgacttcata 550

 gcagatgcgg atgtgggcct aaaaagcatc gtcaaggagt gcgggaaccg 600

 ctgctgtgcc tttagcaaca gcaagaaaac cagtaaggca gagaaggaaa 650

 gtcaagtgca ggagttggtg gagctgatag agaaaatggt gcagtgcaac 700

 gaaggggctt acttttctga tgacatatac aaggacacag aggaaaggct 750

 gaaacaacgg gaagaggttt tgaggaaaat ctacactgac caattaaatg 800

 aagaaattaa actagtagaa gaggataagc ataaatcaga ggaagaaaag 850

 gagaaagaaa ttaaattact aaaattaaaa tatgatgaaa aaataaaaaa 900

 tataagggaa gaagctgaga gaaatatatt taaagatgtt tttaatagga 950

 tttggaagat gctttcagaa atatggcata ggtttttgtc gaaatgtaag 1000

 ttttattctt cctaatttac tgtgatttgt taatggatga attgtatttt 1050

 gcaaagatag ttagagaaat acctccttcc ccttagcttt attaaggtat 1100

 cattgataaa taaaaataaa atatgtttaa tgtatataat gtgattttta 1150

 aatatatata tatatataca cacattgtga aataatgaaa taaaggtaat 1200

 taacacatct aaaaaaaaaa aaaaaaaaaa 1230

<210> 4607
<211> 300
<212> PRT
<213> Homo sapien

<400> 4607
 Met Ala Glu Ser Glu Asp Arg Ser Leu Arg Ile Val Leu Val Gly
   1               5                  10                  15

 Lys Thr Gly Ser Gly Lys Ser Ala Thr Ala Asn Thr Ile Leu Gly
                  20                  25                  30

 Glu Glu Ile Phe Asp Ser Arg Ile Ala Ala Gln Ala Val Thr Lys
                  35                  40                  45

 Asn Cys Gln Lys Ala Ser Arg Glu Trp Gln Gly Arg Asp Leu Leu
                  50                  55                  60

 Val Val Asp Thr Pro Gly Leu Phe Asp Thr Lys Glu Ser Leu Asp
                  65                  70                  75

 Thr Thr Cys Lys Glu Ile Ser Arg Cys Ile Ile Ser Ser Cys Pro
                  80                  85                  90

 Gly Pro His Ala Ile Val Leu Val Leu Leu Leu Gly Arg Tyr Thr
                  95                 100                 105

 Glu Glu Glu Gln Lys Thr Val Ala Leu Ile Lys Ala Val Phe Gly
                 110                 115                 120

 Lys Ser Ala Met Lys His Met Val Ile Leu Phe Thr Arg Lys Glu
                 125                 130                 135

 Glu Leu Glu Gly Gln Ser Phe His Asp Phe Ile Ala Asp Ala Asp
                 140                 145                 150

 Val Gly Leu Lys Ser Ile Val Lys Glu Cys Gly Asn Arg Cys Cys
                 155                 160                 165

 Ala Phe Ser Asn Ser Lys Lys Thr Ser Lys Ala Glu Lys Glu Ser
                 170                 175                 180

 Gln Val Gln Glu Leu Val Glu Leu Ile Glu Lys Met Val Gln Cys
                 185                 190                 195

 Asn Glu Gly Ala Tyr Phe Ser Asp Asp Ile Tyr Lys Asp Thr Glu
                 200                 205                 210

 Glu Arg Leu Lys Gln Arg Glu Glu Val Leu Arg Lys Ile Tyr Thr
                 215                 220                 225

 Asp Gln Leu Asn Glu Glu Ile Lys Leu Val Glu Glu Asp Lys His
                 230                 235                 240

 Lys Ser Glu Glu Glu Lys Glu Lys Glu Ile Lys Leu Leu Lys Leu
                 245                 250                 255

 Lys Tyr Asp Glu Lys Ile Lys Asn Ile Arg Glu Glu Ala Glu Arg
                 260                 265                 270

 Asn Ile Phe Lys Asp Val Phe Asn Arg Ile Trp Lys Met Leu Ser
                 275                 280                 285

 Glu Ile Trp His Arg Phe Leu Ser Lys Cys Lys Phe Tyr Ser Ser
                 290                 295                 300

<210> 4608
<211> 1772
<212> DNA
<213> Homo sapien

<400> 4608
 agcgggtgcg gtccgtcggt ggcctagaga tgctgctgcc gcggttgcag 50

 ttgtcgcgca cgcctctgcc cgccagcccg ctccaccgcc gtagcgcccg 100

 agtgtcgggg ggcgcacccg agtcgggcca tgaggccggg aaccgcgcta 150

 caggcggtgc tgctggccgt gctgctggtg gggctgcggg ccgcgacggg 200

 tcgcctgctg agtgggcagc cagtctgccg gggagggaca cagaggcctt 250

 gttataaagt catttacttc catgatactt ctcgaagact gaactttgag 300

 gaagccaaag aagcctgcag gagggatgga ggccagctag tcagcatcga 350

 gtctgaagat gaacagaaac tgatagaaaa gttcattgaa aacctcttgc 400

 catctgatgg tgacttctgg attgggctca ggaggcgtga ggagaaacaa 450

 agcaatagca cagcctgcca ggacctttat gcttggactg atggcagcat 500

 atcacaattt aggaactggt atgtggatga gccgtcctgc ggcagcgagg 550

 tctgcgtggt catgtaccat cagccatcgg cacccgctgg catcggaggc 600

 ccctacatgt tccagtggaa tgatgaccgg tgcaacatga agaacaattt 650

 catttgcaaa tattctgatg agaaaccagc agttccttct agagaagctg 700

 aaggtgagga aacagagctg acaacacctg tacttccaga agaaacacag 750

 gaagaagatg ccaaaaaaac atttaaagaa agtagagaag ctgccttgaa 800

 tctggcctac atcctaatcc ccagcattcc ccttctcctc ctccttgtgg 850

 tcaccacagt tgtatgttgg gtttggatct gtagaaaaag aaaacgggag 900

 cagccagacc ctagcacaaa gaagcaacac accatctggc cctctcctca 950

 ccagggaaac agcccggacc tagaggtcta caatgtcata agaaaacaaa 1000

 gcgaagctga cttagctgag acccggccag acctgaagaa tatttcattc 1050

 cgagtgtgtt cgggagaagc cactcccgat gacatgtctt gtgactatga 1100

 caacatggct gtgaacccat cagaaagtgg gtttatgact ctggtgagcg 1150

 tggagagtgg atttgtgacc aatgacattt atgagttctc cccagaccaa 1200

 atggggagga gtaaggagtc tggatgggtg gaaaatgaaa tatatggtta 1250

 ttaggacata taaaaaactg aaactgacaa caatggaaaa gaaatgataa 1300

 gcaaaatcct cttattttct ataaggaaaa tacacagaag gtctatgaac 1350

 aagcttagat caggtcctgt ggatgagcat gtggtcccca cgacctcctg 1400

 ttggaccccc acgttttggc tgtatccttt atcccagcca gtcatccagc 1450

 tcgaccttat gagaaggtac cttgcccagg tctggcacat agtagagtct 1500

 caataaatgt cacttggttg gttgtatcta acttttaagg gacagagctt 1550

 tacctggcag tgataaagat gggctgtgga gcttggaaaa ccacctctgt 1600

 tttccttgct ctatacagca gcacatatta tcatacagac agaaaatcca 1650

 gaatcttttc aaagcccaca tatggtagca caggttggcc tgtgcatcgg 1700

 caattctcat atctgttttt ttcaaagaat aaaatcaaat aaagagcagg 1750

 aaacagaaaa aaaaaaaaaa aa 1772

<210> 4609
<211> 374
<212> PRT
<213> Homo sapien

<400> 4609
 Met Arg Pro Gly Thr Ala Leu Gln Ala Val Leu Leu Ala Val Leu
   1               5                  10                  15

 Leu Val Gly Leu Arg Ala Ala Thr Gly Arg Leu Leu Ser Gly Gln
                  20                  25                  30

 Pro Val Cys Arg Gly Gly Thr Gln Arg Pro Cys Tyr Lys Val Ile
                  35                  40                  45

 Tyr Phe His Asp Thr Ser Arg Arg Leu Asn Phe Glu Glu Ala Lys
                  50                  55                  60

 Glu Ala Cys Arg Arg Asp Gly Gly Gln Leu Val Ser Ile Glu Ser
                  65                  70                  75

 Glu Asp Glu Gln Lys Leu Ile Glu Lys Phe Ile Glu Asn Leu Leu
                  80                  85                  90

 Pro Ser Asp Gly Asp Phe Trp Ile Gly Leu Arg Arg Arg Glu Glu
                  95                 100                 105

 Lys Gln Ser Asn Ser Thr Ala Cys Gln Asp Leu Tyr Ala Trp Thr
                 110                 115                 120

 Asp Gly Ser Ile Ser Gln Phe Arg Asn Trp Tyr Val Asp Glu Pro
                 125                 130                 135

 Ser Cys Gly Ser Glu Val Cys Val Val Met Tyr His Gln Pro Ser
                 140                 145                 150

 Ala Pro Ala Gly Ile Gly Gly Pro Tyr Met Phe Gln Trp Asn Asp
                 155                 160                 165

 Asp Arg Cys Asn Met Lys Asn Asn Phe Ile Cys Lys Tyr Ser Asp
                 170                 175                 180

 Glu Lys Pro Ala Val Pro Ser Arg Glu Ala Glu Gly Glu Glu Thr
                 185                 190                 195

 Glu Leu Thr Thr Pro Val Leu Pro Glu Glu Thr Gln Glu Glu Asp
                 200                 205                 210

 Ala Lys Lys Thr Phe Lys Glu Ser Arg Glu Ala Ala Leu Asn Leu
                 215                 220                 225

 Ala Tyr Ile Leu Ile Pro Ser Ile Pro Leu Leu Leu Leu Leu Val
                 230                 235                 240

 Val Thr Thr Val Val Cys Trp Val Trp Ile Cys Arg Lys Arg Lys
                 245                 250                 255

 Arg Glu Gln Pro Asp Pro Ser Thr Lys Lys Gln His Thr Ile Trp
                 260                 265                 270

 Pro Ser Pro His Gln Gly Asn Ser Pro Asp Leu Glu Val Tyr Asn
                 275                 280                 285

 Val Ile Arg Lys Gln Ser Glu Ala Asp Leu Ala Glu Thr Arg Pro
                 290                 295                 300

 Asp Leu Lys Asn Ile Ser Phe Arg Val Cys Ser Gly Glu Ala Thr
                 305                 310                 315

 Pro Asp Asp Met Ser Cys Asp Tyr Asp Asn Met Ala Val Asn Pro
                 320                 325                 330

 Ser Glu Ser Gly Phe Met Thr Leu Val Ser Val Glu Ser Gly Phe
                 335                 340                 345

 Val Thr Asn Asp Ile Tyr Glu Phe Ser Pro Asp Gln Met Gly Arg
                 350                 355                 360

 Ser Lys Glu Ser Gly Trp Val Glu Asn Glu Ile Tyr Gly Tyr
                 365                 370

<210> 4610
<211> 1959
<212> DNA
<213> Homo sapien

<400> 4610
 atcacttggc tcttctctga tatgaactgg gcagcatcta aatgtatctt 50

 tcttgatttt gttgtctctt tgcatagagc atatcttgtg aaaacagaaa 100

 tatccatgta atggtttttt cttgtagtga ccgctcgaaa ttgcttgagc 150

 aacatagaga taatgggcag gggtccctgt gtgaagcacc tagaggctgg 200

 aaagctgatg gcaaagctgg aggggtgagg cagggagagg ataaacacag 250

 tggaaatgca ggaggaaagc tgtgctctgt ggtggcctaa ttacaaggac 300

 ctgccctaca gccagaatca gccagcaaat gcttttgtaa aggaactaaa 350

 agaaagggaa aagaggaagt aaacaaaagg tcccttttca gagagggaac 400

 cagtgggaga cttaagagca aggaacaacc catttcgtcg ttatggtaag 450

 tggagattat tccttgggcc tgaatgactt gaatgtttcc ccgcctgagc 500

 taacagtcca tgtgggtgat tcagctctga tgggatgtgt tttccagagc 550

 acagaagaca aatgtatatt caagatagac tggactctgt caccaggaga 600

 gcacgccaag gacgaatatg tgctatacta ttactccaat ctcagtgtgc 650

 ctattgggcg cttccagaac cgcgtacact tgatggggga caacttatgc 700

 aatgatggct ctctcctgct ccaagatgtg caagaggctg accagggaac 750

 ctatatctgt gaaatccgcc tcaaagggga gagccaggtg ttcaagaagg 800

 cggtggtact gcatgtgctt ccagaggagc ccaaagagct catggtccat 850

 gtgggtggat tgattcagat gggatgtgtt ttccagagca cagaagtgaa 900

 acacgtgacc aaggtagaat ggatattttc aggacggcgc gcaaaggagg 950

 agattgtatt tcgttactac cacaaactca ggatgtctgc ggagtactcc 1000

 cagagctggg gccacttcca gaatcgtgtg aacctggtgg gggacatttt 1050

 ccgcaatgac ggttccatca tgcttcaagg agtgagggag tcagatggag 1100

 gaaactacac ctgcagtatc cacctaggga acctggtgtt caagaaaacc 1150

 attgtgctgc atgtcagccc ggaagagcct cgaacactgg tgaccccggc 1200

 agccctgagg cctctggtct tgggtggtaa tcagttggtg atcattgtgg 1250

 gaattgtctg tgccacaatc ctgctgctcc ctgttctgat attgatcgtg 1300

 aagaagacct gtggaaataa gagttcagtg aattctacag tcttggtgaa 1350

 gaacacgaag aagactaatc cagagataaa agaaaaaccc tgccattttg 1400

 aaagatgtga aggggagaaa cacatttact ccccaataat tgtacgggag 1450

 gtgatcgagg aagaagaacc aagtgaaaaa tcagaggcca cctacatgac 1500

 catgcaccca gtttggcctt ctctgaggtc agatcggaac aactcacttg 1550

 aaaaaaagtc aggtggggga atgccaaaaa cacagcaagc cttttgagaa 1600

 gaatggagag tcccttcatc tcagcagcgg tggagactct ctcctgtgtg 1650

 tgtcctgggc cactctacca gtgatttcag actcccgctc tcccagctgt 1700

 cctcctgtct cattgtttgg tcaatacact gaagatggag aatttggagc 1750

 ctggcagaga gactggacag ctctggagga acaggcctgc tgaggggagg 1800

 ggagcatgga cttggcctct ggagtgggac actggccctg ggaaccaggc 1850

 tgagctgagt ggcctcaaac cccccgttgg atcagaccct cctgtgggca 1900

 gggttcttag tggatgagtt actgggaaga atcagagata aaaaccaacc 1950

 caaatcatt 1959

<210> 4611
<211> 384
<212> PRT
<213> Homo sapien

<400> 4611
 Met Val Ser Gly Asp Tyr Ser Leu Gly Leu Asn Asp Leu Asn Val
   1               5                  10                  15

 Ser Pro Pro Glu Leu Thr Val His Val Gly Asp Ser Ala Leu Met
                  20                  25                  30

 Gly Cys Val Phe Gln Ser Thr Glu Asp Lys Cys Ile Phe Lys Ile
                  35                  40                  45

 Asp Trp Thr Leu Ser Pro Gly Glu His Ala Lys Asp Glu Tyr Val
                  50                  55                  60

 Leu Tyr Tyr Tyr Ser Asn Leu Ser Val Pro Ile Gly Arg Phe Gln
                  65                  70                  75

 Asn Arg Val His Leu Met Gly Asp Asn Leu Cys Asn Asp Gly Ser
                  80                  85                  90

 Leu Leu Leu Gln Asp Val Gln Glu Ala Asp Gln Gly Thr Tyr Ile
                  95                 100                 105

 Cys Glu Ile Arg Leu Lys Gly Glu Ser Gln Val Phe Lys Lys Ala
                 110                 115                 120

 Val Val Leu His Val Leu Pro Glu Glu Pro Lys Glu Leu Met Val
                 125                 130                 135

 His Val Gly Gly Leu Ile Gln Met Gly Cys Val Phe Gln Ser Thr
                 140                 145                 150

 Glu Val Lys His Val Thr Lys Val Glu Trp Ile Phe Ser Gly Arg
                 155                 160                 165

 Arg Ala Lys Glu Glu Ile Val Phe Arg Tyr Tyr His Lys Leu Arg
                 170                 175                 180

 Met Ser Ala Glu Tyr Ser Gln Ser Trp Gly His Phe Gln Asn Arg
                 185                 190                 195

 Val Asn Leu Val Gly Asp Ile Phe Arg Asn Asp Gly Ser Ile Met
                 200                 205                 210

 Leu Gln Gly Val Arg Glu Ser Asp Gly Gly Asn Tyr Thr Cys Ser
                 215                 220                 225

 Ile His Leu Gly Asn Leu Val Phe Lys Lys Thr Ile Val Leu His
                 230                 235                 240

 Val Ser Pro Glu Glu Pro Arg Thr Leu Val Thr Pro Ala Ala Leu
                 245                 250                 255

 Arg Pro Leu Val Leu Gly Gly Asn Gln Leu Val Ile Ile Val Gly
                 260                 265                 270

 Ile Val Cys Ala Thr Ile Leu Leu Leu Pro Val Leu Ile Leu Ile
                 275                 280                 285

 Val Lys Lys Thr Cys Gly Asn Lys Ser Ser Val Asn Ser Thr Val
                 290                 295                 300

 Leu Val Lys Asn Thr Lys Lys Thr Asn Pro Glu Ile Lys Glu Lys
                 305                 310                 315

 Pro Cys His Phe Glu Arg Cys Glu Gly Glu Lys His Ile Tyr Ser
                 320                 325                 330

 Pro Ile Ile Val Arg Glu Val Ile Glu Glu Glu Glu Pro Ser Glu
                 335                 340                 345

 Lys Ser Glu Ala Thr Tyr Met Thr Met His Pro Val Trp Pro Ser
                 350                 355                 360

 Leu Arg Ser Asp Arg Asn Asn Ser Leu Glu Lys Lys Ser Gly Gly
                 365                 370                 375

 Gly Met Pro Lys Thr Gln Gln Ala Phe
                 380

<210> 4612
<211> 1635
<212> DNA
<213> Homo sapien

<400> 4612
 gggggtggcg gggacgcgag tggcggccgc ggggccccgg acaagggtcc 50

 gcagagctgc agccttcgag ggccagccct ctccgagtcc ggggctgggt 100

 cccaccagtg acaaggcggc agccccgcgc acaccaaaga gaaagcggct 150

 gtggcggcag cggcagcccc agccatgctg tgttatgtga cgaggccgga 200

 cgcggtgctg atggaggtgg aggtggaggc gaaagccaac ggcgaggact 250

 gcctcaacca ggtgtgcagg cgactgggaa tcatagaagt tgactatttt 300

 ggactgcaat ttacgggtag caaaggtgaa agtttatggc taaacctgag 350

 aaaccggatc tcccagcaga tggatgggct agccccttac aggcttaaac 400

 ttagagtcaa gttcttcgtg gagcctcatc tcatcttaca ggagcagact 450

 aggcatatct ttttcttgca catcaaggag gccctcttgg caggccacct 500

 cttgtgttcc ccagagcagg cagtggaact cagtgccctc ctggcccaga 550

 ccaagtttgg agactacaac cagaacactg ccaagtataa ctatgaggag 600

 ctctgtgcca aggagctctc ctctgccacc ttgaacagca ttgttgcaaa 650

 acataaggag ttggagggga ccagccaggc ttcagctgaa taccaagttt 700

 tgcagattgt gtcggcaatg gaaaactatg gcatagaatg gcattctgtg 750

 cgggatagcg aagggcagag actgctcatt ggggttggac ctgaaggaat 800

 ctcaatttgt aaagatgact ttagcccaat taataggata gcttatcctg 850

 tggtgcagat ggccacccag tcaggaaaga atgtatattt gacggtcacc 900

 aaggaatctg ggaacagcat cgtgctcttg tttaaaatga tcagcaccag 950

 ggcggccagc gggctctacc gagcgataac agagacgcac gcattctaca 1000

 ggtgtgacac agtgaccagc gccgtgatga tgcagtatag ccgtgacttg 1050

 aagggccact tggcatctct gtttctgaat gaaaacatta accttggcaa 1100

 gaaatatgtc tttgatatta aaagaacatc aaaggaggtg tatgaccatg 1150

 ccaggagggc tctgtacaat gctggcgttg tggacctcgt ttcaagaagc 1200

 aaccagagcc cttcacactc gcctctgaag tcctcagaaa gcagcatgaa 1250

 ctgcagcagc tgcgagggcc tcagctgcca gcagacccgg gtgctgcagg 1300

 agaagctacg caagctgaag gaagccatgc tgtgcatggt gtgctgcgag 1350

 gaggagatca actccacctt ctgtccctgt ggccacactg tgtgctgtga 1400

 gagctgcgcc gcccagctac agtcatgtcc cgtctgcagg tcgcgtgtgg 1450

 agcatgtcca gcacgtctat ctgccaacgc acaccagtct tctcaatctg 1500

 actgtaatct aatctgttgt gcttttgttg gacttggcat gtttccatga 1550

 actgcactat tataaactat taaaatgata gatgttggag aaagtaatta 1600

 ttccaacacc catctgccca tgcgatgtta aaaaa 1635

<210> 4613
<211> 445
<212> PRT
<213> Homo sapien

<400> 4613
 Met Leu Cys Tyr Val Thr Arg Pro Asp Ala Val Leu Met Glu Val
   1               5                  10                  15

 Glu Val Glu Ala Lys Ala Asn Gly Glu Asp Cys Leu Asn Gln Val
                  20                  25                  30

 Cys Arg Arg Leu Gly Ile Ile Glu Val Asp Tyr Phe Gly Leu Gln
                  35                  40                  45

 Phe Thr Gly Ser Lys Gly Glu Ser Leu Trp Leu Asn Leu Arg Asn
                  50                  55                  60

 Arg Ile Ser Gln Gln Met Asp Gly Leu Ala Pro Tyr Arg Leu Lys
                  65                  70                  75

 Leu Arg Val Lys Phe Phe Val Glu Pro His Leu Ile Leu Gln Glu
                  80                  85                  90

 Gln Thr Arg His Ile Phe Phe Leu His Ile Lys Glu Ala Leu Leu
                  95                 100                 105

 Ala Gly His Leu Leu Cys Ser Pro Glu Gln Ala Val Glu Leu Ser
                 110                 115                 120

 Ala Leu Leu Ala Gln Thr Lys Phe Gly Asp Tyr Asn Gln Asn Thr
                 125                 130                 135

 Ala Lys Tyr Asn Tyr Glu Glu Leu Cys Ala Lys Glu Leu Ser Ser
                 140                 145                 150

 Ala Thr Leu Asn Ser Ile Val Ala Lys His Lys Glu Leu Glu Gly
                 155                 160                 165

 Thr Ser Gln Ala Ser Ala Glu Tyr Gln Val Leu Gln Ile Val Ser
                 170                 175                 180

 Ala Met Glu Asn Tyr Gly Ile Glu Trp His Ser Val Arg Asp Ser
                 185                 190                 195

 Glu Gly Gln Arg Leu Leu Ile Gly Val Gly Pro Glu Gly Ile Ser
                 200                 205                 210

 Ile Cys Lys Asp Asp Phe Ser Pro Ile Asn Arg Ile Ala Tyr Pro
                 215                 220                 225

 Val Val Gln Met Ala Thr Gln Ser Gly Lys Asn Val Tyr Leu Thr
                 230                 235                 240

 Val Thr Lys Glu Ser Gly Asn Ser Ile Val Leu Leu Phe Lys Met
                 245                 250                 255

 Ile Ser Thr Arg Ala Ala Ser Gly Leu Tyr Arg Ala Ile Thr Glu
                 260                 265                 270

 Thr His Ala Phe Tyr Arg Cys Asp Thr Val Thr Ser Ala Val Met
                 275                 280                 285

 Met Gln Tyr Ser Arg Asp Leu Lys Gly His Leu Ala Ser Leu Phe
                 290                 295                 300

 Leu Asn Glu Asn Ile Asn Leu Gly Lys Lys Tyr Val Phe Asp Ile
                 305                 310                 315

 Lys Arg Thr Ser Lys Glu Val Tyr Asp His Ala Arg Arg Ala Leu
                 320                 325                 330

 Tyr Asn Ala Gly Val Val Asp Leu Val Ser Arg Ser Asn Gln Ser
                 335                 340                 345

 Pro Ser His Ser Pro Leu Lys Ser Ser Glu Ser Ser Met Asn Cys
                 350                 355                 360

 Ser Ser Cys Glu Gly Leu Ser Cys Gln Gln Thr Arg Val Leu Gln
                 365                 370                 375

 Glu Lys Leu Arg Lys Leu Lys Glu Ala Met Leu Cys Met Val Cys
                 380                 385                 390

 Cys Glu Glu Glu Ile Asn Ser Thr Phe Cys Pro Cys Gly His Thr
                 395                 400                 405

 Val Cys Cys Glu Ser Cys Ala Ala Gln Leu Gln Ser Cys Pro Val
                 410                 415                 420

 Cys Arg Ser Arg Val Glu His Val Gln His Val Tyr Leu Pro Thr
                 425                 430                 435

 His Thr Ser Leu Leu Asn Leu Thr Val Ile
                 440                 445

<210> 4614
<211> 1103
<212> DNA
<213> Homo sapien

<400> 4614
 gtcttaatga gcaacagcaa cagcagtctc cagttaagaa agagagaatt 50

 aaatacagca gagatttcct gttgaagctc tcaagtgttt ccatctgcag 100

 aaaaaaacca gactttctgc ctgatcatcc cattgtactg caaaaaccag 150

 aaaacaacca aagttttaag tagcatttta agaacagatg aatttaagtt 200

 tggacatctg caaatgaggt ggatctagca acaataactg taatggactg 250

 tgacaattca atttattctt aattttgatg gttggctatt tgacttctct 300

 aaaaatgaga aagagctatt ttaaaatata aagaattttc taatcagttt 350

 cagctttgca ggaggtttcc tgcataaatt gggaagtaac actggaaagt 400

 aggaatttgg ttagtgaagt gggaagactg tatatttata atttgcatac 450

 tacttgcaat tttttgtttt tcatcacttg taataatgga atggaaatgt 500

 aagctgtaaa gactctcaaa tataaaatat ttgctacagt gtatatatgg 550

 tacataattg cttgttgctt ttaaagttcc ttctgttgtt ctgcttccca 600

 ctgatttcat accagctcat gaatggatca ttacagtctc tccagaggct 650

 tagaatgatt cagaatgttc aatgcatagt tctcaataaa caggaggcag 700

 aatttttaat gggtatttct tttcagatat atgattggtc tctaggtttt 750

 tgataataat atggtcttaa attcataatt actagcagag attgataatt 800

 tggaaacaat ggtagtgaat gaaactgaag ttgaaaaacg gctgctactt 850

 atgtcactaa tcagaccata tgaatagcag aagttgagca atttcaaagt 900

 aaaactgata tttttatttc caaaggaatt tagacatttg aaaataattg 950

 acatacatta agttttaatt cgataatttc ttatatatgg atgaacaatt 1000

 tttgggttta agcttttaat tcctagaaat tttatacatt aaatctcctg 1050

 caatttgtca ctctggatgt tactgtttaa aaaaaaaaaa aaaaaactcg 1100

 tag 1103

<210> 4615
<211> 68
<212> PRT
<213> Homo sapien

<400> 4615
 Met Val His Asn Cys Leu Leu Leu Leu Lys Phe Leu Leu Leu Phe
   1               5                  10                  15

 Cys Phe Pro Leu Ile Ser Tyr Gln Leu Met Asn Gly Ser Leu Gln
                  20                  25                  30

 Ser Leu Gln Arg Leu Arg Met Ile Gln Asn Val Gln Cys Ile Val
                  35                  40                  45

 Leu Asn Lys Gln Glu Ala Glu Phe Leu Met Gly Ile Ser Phe Gln
                  50                  55                  60

 Ile Tyr Asp Trp Ser Leu Gly Phe
                  65

<210> 4616
<211> 8107
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 6034-6155
<223> Unknown base

<400> 4616
 atgcagaaga gcgtgcgcta caacgagggg cacgccctgt acctggcctt 50

 tctggcgcgc aaggagggca ccaagcgcgg cttcctgagt aagaagacgg 100

 ccgaggcgag ccgctggcac gagaagtggt tcgccctcta ccagaatgtg 150

 ctcttctact tcgagggcga gcagagctgc cgcccggcgg gcatgtacct 200

 cctggagggc tgcagctgcg aacgaacgcc cgcgccaccc agggccggcg 250

 ccgggcaggg aggcgtccga gacgcgctgg acaagcagta ttactttact 300

 gttctttttg gccatgaagg tcagaagcca ctggagctgc gctgtgagga 350

 ggagcaggat ggtaaagagt ggatggaggc cattcaccaa gccagttatg 400

 cagacatttt gattgagagg gaagtattaa tgcagaagta cattcatcta 450

 gttcagatcg tagagacaga aaaaattgca gctaaccaac tccgacatca 500

 acttgaagat caagacacag aaatcgaaag gcttaaatca gagattattg 550

 ctcttaataa aaccaaagaa cgaatgcgac cttaccaaag caaccaagaa 600

 gacgaagatc cagacatcaa gaagattaaa aaggttcaga gcttcatgcg 650

 aggatggttg tgcagaagga aatggaagac catcgtgcag gattacattt 700

 gttctcctca tgctgaaagt atgaggaaga gaaaccagat tgtgttcacc 750

 atggtggagg cagagtcaga gtacgttcac cagctctaca tcctggtcaa 800

 tggctttctc cggcccctgc gtatggccgc cagctccaag aagcccccca 850

 tcagccacga cgacgtcagc agtatttttc ttaacagtga aacaatcatg 900

 tttcttcatg aaatatttca tcaaggacta aaggcaagga tagcaaactg 950

 gcccacttta attttagctg atctgtttga tattttgctc cccatgctga 1000

 acatttatca agaatttgtg cgtaatcacc agtacagcct gcaagttctc 1050

 gccaattgta agcaaaacag agattttgac aaactcttaa aacagtatga 1100

 agccaatcca gcctgtgagg ggaggatgct ggagacattc ttgacctatc 1150

 ccatgtttca gatccccaga tatatcatca cactccatga gctccttgct 1200

 cacacacccc atgagcatgt ggaaaggaaa agcctggagt ttgccaaatc 1250

 aaagctagag gaactatcca gagtaatgca cgatgaagtc agcgacactg 1300

 aaaacataag gaaaaacctt gccatcgaaa gaatgatcgt ggagggctgt 1350

 gacatcttgc tggacaccag ccaaacgttc atccgccaag gttctcttat 1400

 tcaagtacct tccgttgaga gggggaaact tagtaaagtt cgcctgggtt 1450

 cgttgtcttt gaaaaaggaa ggagagagac aatgcttctt atttacaaaa 1500

 cactttttaa tatgtacaag aagttcagga gggaagcttc atctgctcaa 1550

 gacaggtggg gttctgtctc taatagactg cacattgatt gaggagccag 1600

 atgcaagcga tgatgactct aaaggttctg ggcaagtgtt tgggcacctg 1650

 gattttaaaa tagtggtgga gcctcctgac gctgccgcct tcactgttgt 1700

 cttgttagca ccctcacgcc aggagaaagc tgcctggatg agtgacatca 1750

 gtcagtgtgt ggacaatata cgatgtaatg gtttaatgac tatagtgttt 1800

 gaagagaatt ccaaagtcac tgtgccacat atgattaagt ctgatgcccg 1850

 tcttcataaa gacgacactg acatttgctt cagtaaaaca ctcaactcct 1900

 gcaaagtgcc ccagatccgt tatgccagcg tggagcgcct cttggaacga 1950

 ctgacagact tgcggtttct gtagtattga tttcctcaac acctttctgc 2000

 acacctatcg tattttcact actgccgctg tggtgctggg gaaactctcc 2050

 gacatataca agaggccttt cacctccatc cctgtcaggt cattggaatt 2100

 gttttttgct accagccaga acaacagagg tgaacatttg gtggatggca 2150

 aatccccacg tctgtgtcgc aaattctctt ccccgccacc actggctgtg 2200

 tccagaacat cttccccagt gagggccaga aagctgtctt tgacttctcc 2250

 cttgaactca aagataggag cattggacct gacaacttcc agcagtccca 2300

 ccaccaccac ccagagtccc gctgcgtctc caccaccaca cactggtcag 2350

 ataccactgg atctcagcag aggcctctct tctccagagc aaagcccggg 2400

 aacggtagaa gagaatgtcg ataacccacg cgtggatctg tgtaacaagc 2450

 taaaacgaag tattcaaaaa gcagtcctag agtctgcacc agcggaccga 2500

 gcaggagtgg aaagctcccc tgcagcggac accacagaac tttcaccttg 2550

 cagatccccc tcaactcctc ggcacctccg ctatcgacag cctggaggac 2600

 agacggcgga caatgcccac tgctctgttt caccggcttc tgcttttgca 2650

 atagccacag ctgcagcagg acatgggagt ccaccaggct ttaacaacac 2700

 cgagagaaca tgtgataaag agtttattat acggagaacg gctaccaatc 2750

 gagttctgaa cgtcctccgt cactgggtct caaagcacgc acaggatttc 2800

 gaactcaaca atgaactaaa gatgaatgtc ctaaatttgc tagaagaagt 2850

 tttgcgagac ccagaccttc ttccccaaga aaggaaagcc gccgcgaata 2900

 tcctcagggc cctttcacaa gatgaccaag atgacatcca cctaaaatta 2950

 gaggatataa ttcaaatgac tgactgcatg aaggccgaat gctttgagtc 3000

 cttgtcggcc atggagctgg cagaacagat caccctcctg gaccatgtca 3050

 ttttcagaag cattccctat cgaggagttt cttgggcagg ggtggatgaa 3100

 gctggataaa aacgaaagaa ctccttacat tatgaaaacc agccaacact 3150

 tcaatgacat gagtaacctg gtggcctccc agataatgaa ctatgctgat 3200

 gtcagctccc gtgccaacgc catcgagaaa tgggtggcag tggcggacat 3250

 ctgccgatgc ctgcacaact acaacggcgt gctggagatc acctcggcct 3300

 taaacagaag tgccatctac aggctgaaga aaacctgggc caaggtctct 3350

 aagcagacaa aagctctaat ggacaaactt caaaagactg tttcctctga 3400

 aggaagattt aaaaatctta gagaaaccct taaaaattgt aaccctcctg 3450

 cagttcctta tcttgggatg tacttgacag acctggcatt tattgaagaa 3500

 ggaacaccaa actttactga ggaaggcctt gtcaatttct ccaaaatgag 3550

 aatgatatca cacatcatca gagagatacg ccagttccag cagacttcct 3600

 acagaataga tcatcagcca aaggtcgcac agtacttgct tgacaaagac 3650

 cttatcatag atgaagatac gctatatgag ctgtcactaa aaattgaacc 3700

 tcgactccct gcttgaagat ctggccttgc ccctgagtcc acgggatgtt 3750

 catggaaagc aggacagaca gaattgtgta tgccttgcct atcacggtac 3800

 agcacgaagc caggctcctt tctccaccaa agaagatgga accagactgg 3850

 aattctgtct ccagagagaa acccagctgt ttgggtcaaa gacagatgct 3900

 tcagacttgg gtgggaaggt gaaagatggc tatttagaaa gctggtggca 3950

 cgttttacat aagggaatgt cagatgggag atgctagttg ccattttaac 4000

 aaagcaggta aatcggtaaa ttttaaactc tgtccatgtt ctgatagaac 4050

 tcagggacaa ggatccatga aaaagacctg tgatgtttct ctggcgcttt 4100

 actggcctgg gcacacctac caatcttcta ggatttgact ggttccatta 4150

 catttccttt tggtataagc ttcacagaaa agctgacact tcctctacag 4200

 agatggacca aaacataagc aatttcagtc tacagcatgt gcatggttgt 4250

 cagtgcattc taaatatttc tatgtgagga atggtacctt ctgaaactgc 4300

 ctttccagtc tttaggcaat gggataggaa agaaagaatg aaacacaaat 4350

 ggatttgtat gtaacatttc cttaattaaa tgcagtaggc tgtgccccag 4400

 aggattccag acagtggctg gctgaggtgg gtggggagct tttccttgag 4450

 actgttggtc ctaagaagcc agcccttttg gagaggcagc tgcaaaaagg 4500

 tgcacgccca tctcaccgac aaaactgtgg aacagaaggc caccaagtgc 4550

 tgtggggaat catgggtttc agtgctgagt gaaaatctat acctaaaaat 4600

 catctctgca ccttgctttg tttgttttct ttccccactc atagtactgc 4650

 aggaatctat tctcatttac acagaccttt ttttaggctt actatgaaca 4700

 ttggctgtat tttttttaaa cagtttagtg aaattttctt ttcaaaaccc 4750

 acacttccat atgctgttcg tagatctctt tctttaaaaa ctgatgttga 4800

 gagatctctg agaatattat aagtgcatgg gaaatgggcc caaccaccga 4850

 acagctctta cattacaaaa ccaaatgcaa gggttagtcc tgctacctga 4900

 ggctggggaa gtgaccttcc ttttcccaag attgtcagtt gttgaagaaa 4950

 tagggctatc tcattgttta cctccctctt ctcttctcag ggagactgct 5000

 gctttaaaag aaggaagaga aaaaatatag ttctatttcc ctgaacctgt 5050

 tgcacctgac attttctctt agcagcatga aacttattga tgctgacaat 5100

 gaaaaatgga tctgtctggc tgctttccct ctttccttgc actttaatta 5150

 tgttgctaga gctaacagac taataaattc cacctgctgg ctcttaagac 5200

 tcagtgaaag agctagcatt ggtaatgcac catagaggta gagaatgtac 5250

 actttctgca cggtaagtgc catctctgta tgtaactata tagtgaaata 5300

 tcaactaagt aaaagaaaat ataatatttg aagaccattc ccaaaatatt 5350

 ttcaatagtt catattagcc aacagtgtag cactcaaccc aaggagggtt 5400

 ccttatggat gctttctttt tcttttttaa agttgcttga tggttctctt 5450

 tagtttcaaa taagaggttg acgcatcttg atgcatgatg agaagcatgg 5500

 gctgtttgga tcctaacaac gcataacttg tgatttattt ctcagtgctc 5550

 cagaaactga gggtttgaaa taatatgtat cagttgcacc aaacacctca 5600

 aggtcttgca gaagaaaagt aaaggttagc tttcatggct caaaagcata 5650

 gtcctgaagg gtgaactaaa accgggacaa atctgtgaga ggaccacaca 5700

 catactagtt tcgggccaaa caacacgtgg aaaggtgcat gcattctact 5750

 ctgccttgga gttgccagag tccttcagag ggaaagggat ggttctgtgt 5800

 gcactttttc tggaagttcg gactcatttc tttgacccaa atgttccaga 5850

 gacactgcag ccattcttat taacaaaaaa taagacagga gtttccaaat 5900

 gctccttccc ttttggatcg cagcttttct tcaactagtg acaaagcttt 5950

 tgcgcctatt tcctgcagga tgttggaact gccccgcact ggtcatatta 6000

 ggcactgtca attgctatgc tgacttttag gggnnnnnnn nnnnnnnnnn 6050

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 6100

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 6150

 nnnnncacta gcctttcgca tttttgtttg agaattacac cactttctgg 6200

 agtctgcagc cttcctggag ctgcaagagg gcaagagaga gagctccacc 6250

 tctgagggag tgtctgttga tgacctgcac tattcgtgtg ccagctggga 6300

 gaggaatgca cattttaaaa tcccttcaat ttggtcaaat taaaaatccc 6350

 caagagcaat ttgcagtgtt ttttctggtc gttaaagtac ccatcctctt 6400

 ctgcctacac acaaagcatg cattcccagc tgcatctgcc tctagtccat 6450

 tatggagacc catttctaag aggagatggg aggtcaacct ctaacagcca 6500

 agtagcgaac atgtatactg taaaattaac ctagaaaatc agaagaaaaa 6550

 tccaatttca tgctttcgaa tgaatgccca cattttgtac tgtcaacgaa 6600

 attatcttgg agcttttagg ggatgccttt tcgttattaa ctgagacatc 6650

 tagttttgct acagggacaa atctcttacc taatccaata tattatttga 6700

 cagattcagg catgaagtaa aacgtcgtca cttttcctta gtgcttttct 6750

 gaaggaattt aaagacggaa ttttaaacgg ccattgcaat attttcaagt 6800

 ggctctcata ccaagtccca ttactgtttg ttaaatttca gtacgtctta 6850

 aagtactact tataaacaaa tgaaactcag agaaactgaa tcacctggaa 6900

 gagaaaaatc cattatggtc ccatgtggag tgaataatga tggatcagca 6950

 ccctttctct catgttattg tataagacga gacttttggg ccagcagcga 7000

 ttgggcagct tttaaattct taactgaaaa gagtaatgca atacagggat 7050

 tattcccaat aaaattaact tttatttaaa agcaagagat tttacttagc 7100

 tttttttttt caaagtttga ttttatcccc ttgaaaaaaa atctcttcac 7150

 tttaaagtat aaaggttttt aaaaatccaa ttgcaaaatg tattattttt 7200

 acaactatcg aaaaggcata aaagagaaca tactatttat ggctgaaggg 7250

 tatagccagg ctaatgtgca cagagggaat caataaataa aactcttttt 7300

 catttcagta agaaatcaga ttgtaagttt aatggctcca ttatagatac 7350

 caccgtgtaa tagaagactt aagtcaatga aatctaatca gtgtgtcatt 7400

 tctcagcggc cattggtgac ttaaaattaa gatgaggcag agccaaaatg 7450

 gaaaacagtc attttgttgt aggtataaac acatgaacga ttcagaaaat 7500

 tattcatctc agctgccatg cagcatgaca ttaacattag gattgatagc 7550

 actagtctga tctgctcaag gaaaataata gttctattat acttaatgat 7600

 gttggttttt acacagctca tttcattttt cactagaaag ccagttatga 7650

 aagagagctg gcctaggcat cccggccctg agtcctaggc ccagtctcca 7700

 actggaaaac cttaggctgg tgtttacaca tccctgagcc tcagtttcct 7750

 catctgcaaa acggtgtgaa tagtaatccc tgtgctgctt atctcacagg 7800

 gctattgtga ggaccaaatg gattagactg taaactgcaa agtgctgtcc 7850

 gcacatgagg tcatctgatt actgtcctca gatctctttt gtagaggatt 7900

 tcaatgtatt tctttatcat ttgagtgtgt gtgtgatgga cgaatatgtg 7950

 tgtgagtttg agaagcatat cgttcgtgtc cagttacttt gcaaatttgt 8000

 ggacatttgt gattggacag aggggtttgt gctgtggcct aacacttgcc 8050

 aagtgaggtg taggttatgc ctatatgcaa attaaacttc acctttcttg 8100

 aatattc 8107

<210> 4617
<211> 1035
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 6034-6155
<223> Unknown amino acid

<400> 4617
 Met Gln Lys Ser Val Arg Tyr Asn Glu Gly His Ala Leu Tyr Leu
   1               5                  10                  15

 Ala Phe Leu Ala Arg Lys Glu Gly Thr Lys Arg Gly Phe Leu Ser
                  20                  25                  30

 Lys Lys Thr Ala Glu Ala Ser Arg Trp His Glu Lys Trp Phe Ala
                  35                  40                  45

 Leu Tyr Gln Asn Val Leu Phe Tyr Phe Glu Gly Glu Gln Ser Cys
                  50                  55                  60

 Arg Pro Ala Gly Met Tyr Leu Leu Glu Gly Cys Ser Cys Glu Arg
                  65                  70                  75

 Thr Pro Ala Pro Pro Arg Ala Gly Ala Gly Gln Gly Gly Val Arg
                  80                  85                  90

 Asp Ala Leu Asp Lys Gln Tyr Tyr Phe Thr Val Leu Phe Gly His
                  95                 100                 105

 Glu Gly Gln Lys Pro Leu Glu Leu Arg Cys Glu Glu Glu Gln Asp
                 110                 115                 120

 Gly Lys Glu Trp Met Glu Ala Ile His Gln Ala Ser Tyr Ala Asp
                 125                 130                 135

 Ile Leu Ile Glu Arg Glu Val Leu Met Gln Lys Tyr Ile His Leu
                 140                 145                 150

 Val Gln Ile Val Glu Thr Glu Lys Ile Ala Ala Asn Gln Leu Arg
                 155                 160                 165

 His Gln Leu Glu Asp Gln Asp Thr Glu Ile Glu Arg Leu Lys Ser
                 170                 175                 180

 Glu Ile Ile Ala Leu Asn Lys Thr Lys Glu Arg Met Arg Pro Tyr
                 185                 190                 195

 Gln Ser Asn Gln Glu Asp Glu Asp Pro Asp Ile Lys Lys Ile Lys
                 200                 205                 210

 Lys Val Gln Ser Phe Met Arg Gly Trp Leu Cys Arg Arg Lys Trp
                 215                 220                 225

 Lys Thr Ile Val Gln Asp Tyr Ile Cys Ser Pro His Ala Glu Ser
                 230                 235                 240

 Met Arg Lys Arg Asn Gln Ile Val Phe Thr Met Val Glu Ala Glu
                 245                 250                 255

 Ser Glu Tyr Val His Gln Leu Tyr Ile Leu Val Asn Gly Phe Leu
                 260                 265                 270

 Arg Pro Leu Arg Met Ala Ala Ser Ser Lys Lys Pro Pro Ile Ser
                 275                 280                 285

 His Asp Asp Val Ser Ser Ile Phe Leu Asn Ser Glu Thr Ile Met
                 290                 295                 300

 Phe Leu His Glu Ile Phe His Gln Gly Leu Lys Ala Arg Ile Ala
                 305                 310                 315

 Asn Trp Pro Thr Leu Ile Leu Ala Asp Leu Phe Asp Ile Leu Leu
                 320                 325                 330

 Pro Met Leu Asn Ile Tyr Gln Glu Phe Val Arg Asn His Gln Tyr
                 335                 340                 345

 Ser Leu Gln Val Leu Ala Asn Cys Lys Gln Asn Arg Asp Phe Asp
                 350                 355                 360

 Lys Leu Leu Lys Gln Tyr Glu Ala Asn Pro Ala Cys Glu Gly Arg
                 365                 370                 375

 Met Leu Glu Thr Phe Leu Thr Tyr Pro Met Phe Gln Ile Pro Arg
                 380                 385                 390

 Tyr Ile Ile Thr Leu His Glu Leu Leu Ala His Thr Pro His Glu
                 395                 400                 405

 His Val Glu Arg Lys Ser Leu Glu Phe Ala Lys Ser Lys Leu Glu
                 410                 415                 420

 Glu Leu Ser Arg Val Met His Asp Glu Val Ser Asp Thr Glu Asn
                 425                 430                 435

 Ile Arg Lys Asn Leu Ala Ile Glu Arg Met Ile Val Glu Gly Cys
                 440                 445                 450

 Asp Ile Leu Leu Asp Thr Ser Gln Thr Phe Ile Arg Gln Gly Ser
                 455                 460                 465

 Leu Ile Gln Val Pro Ser Val Glu Arg Gly Lys Leu Ser Lys Val
                 470                 475                 480

 Arg Leu Gly Ser Leu Ser Leu Lys Lys Glu Gly Glu Arg Gln Cys
                 485                 490                 495

 Phe Leu Phe Thr Lys His Phe Leu Ile Cys Thr Arg Ser Ser Gly
                 500                 505                 510

 Gly Lys Leu His Leu Leu Lys Thr Gly Gly Val Leu Ser Leu Ile
                 515                 520                 525

 Asp Cys Thr Leu Ile Glu Glu Pro Asp Ala Ser Asp Asp Asp Ser
                 530                 535                 540

 Lys Gly Ser Gly Gln Val Phe Gly His Leu Asp Phe Lys Ile Val
                 545                 550                 555

 Val Glu Pro Pro Asp Ala Ala Ala Phe Thr Val Val Leu Leu Ala
                 560                 565                 570

 Pro Ser Arg Gln Glu Lys Ala Ala Trp Met Ser Asp Ile Ser Gln
                 575                 580                 585

 Cys Val Asp Asn Ile Arg Cys Asn Gly Leu Met Thr Ile Val Phe
                 590                 595                 600

 Glu Glu Asn Ser Lys Val Thr Val Pro His Met Ile Lys Ser Asp
                 605                 610                 615

 Ala Arg Leu His Lys Asp Asp Thr Asp Ile Cys Phe Ser Lys Thr
                 620                 625                 630

 Leu Asn Ser Cys Lys Val Pro Gln Ile Arg Tyr Ala Ser Val Glu
                 635                 640                 645

 Arg Leu Leu Glu Arg Leu Thr Asp Leu Arg Phe Leu Ser Ile Asp
                 650                 655                 660

 Phe Leu Asn Thr Phe Leu His Thr Tyr Arg Ile Phe Thr Thr Ala
                 665                 670                 675

 Ala Val Val Leu Gly Lys Leu Ser Asp Ile Tyr Lys Arg Pro Phe
                 680                 685                 690

 Thr Ser Ile Pro Val Arg Ser Leu Glu Leu Phe Phe Ala Thr Ser
                 695                 700                 705

 Gln Asn Asn Arg Gly Glu His Leu Val Asp Gly Lys Ser Pro Arg
                 710                 715                 720

 Leu Cys Arg Lys Phe Ser Ser Pro Pro Pro Leu Ala Val Ser Arg
                 725                 730                 735

 Thr Ser Ser Pro Val Arg Ala Arg Lys Leu Ser Leu Thr Ser Pro
                 740                 745                 750

 Leu Asn Ser Lys Ile Gly Ala Leu Asp Leu Thr Thr Ser Ser Ser
                 755                 760                 765

 Pro Thr Thr Thr Thr Gln Ser Pro Ala Ala Ser Pro Pro Pro His
                 770                 775                 780

 Thr Gly Gln Ile Pro Leu Asp Leu Ser Arg Gly Leu Ser Ser Pro
                 785                 790                 795

 Glu Gln Ser Pro Gly Thr Val Glu Glu Asn Val Asp Asn Pro Arg
                 800                 805                 810

 Val Asp Leu Cys Asn Lys Leu Lys Arg Ser Ile Gln Lys Ala Val
                 815                 820                 825

 Leu Glu Ser Ala Pro Ala Asp Arg Ala Gly Val Glu Ser Ser Pro
                 830                 835                 840

 Ala Ala Asp Thr Thr Glu Leu Ser Pro Cys Arg Ser Pro Ser Thr
                 845                 850                 855

 Pro Arg His Leu Arg Tyr Arg Gln Pro Gly Gly Gln Thr Ala Asp
                 860                 865                 870

 Asn Ala His Cys Ser Val Ser Pro Ala Ser Ala Phe Ala Ile Ala
                 875                 880                 885

 Thr Ala Ala Ala Gly His Gly Ser Pro Pro Gly Phe Asn Asn Thr
                 890                 895                 900

 Glu Arg Thr Cys Asp Lys Glu Phe Ile Ile Arg Arg Thr Ala Thr
                 905                 910                 915

 Asn Arg Val Leu Asn Val Leu Arg His Trp Val Ser Lys His Ala
                 920                 925                 930

 Gln Asp Phe Glu Leu Asn Asn Glu Leu Lys Met Asn Val Leu Asn
                 935                 940                 945

 Leu Leu Glu Glu Val Leu Arg Asp Pro Asp Leu Leu Pro Gln Glu
                 950                 955                 960

 Arg Lys Ala Ala Ala Asn Ile Leu Arg Ala Leu Ser Gln Asp Asp
                 965                 970                 975

 Gln Asp Asp Ile His Leu Lys Leu Glu Asp Ile Ile Gln Met Thr
                 980                 985                 990

 Asp Cys Met Lys Ala Glu Cys Phe Glu Ser Leu Ser Ala Met Glu
                 995                1000                1005

 Leu Ala Glu Gln Ile Thr Leu Leu Asp His Val Ile Phe Arg Ser
                1010                1015                1020

 Ile Pro Tyr Arg Gly Val Ser Trp Ala Gly Val Asp Glu Ala Gly
                1025                1030                1035

<210> 4618
<211> 1745
<212> DNA
<213> Homo sapien

<400> 4618
 ggggatgccc gttcgctcgg gatcaggaac ggtgagctcc tgggaccgca 50

 atgccctgag aacgcagccg ggtgctgagc ctccggagtc cggtagctga 100

 atgaaatacg cagggatcac cagccggacc caaatcttgc gtccctgcca 150

 gcatcctgga gtcctaagag gcagggattg gagcggacag gatctcagaa 200

 ctctggtccc gggcgcacaa cggcggagtc gctgttcctg gtgctgaaac 250

 gctcagtcct ggaagaacgt ggccgcctgc ccgcctggta ccgcgccgcg 300

 gccgctgcgg ggaactgtcc agtgctgaaa acggatgcgg cccggcccgc 350

 agagctcaga cccaagcctg ccgcacccag cggagctcga accgagctcc 400

 tggaagcgct gacgcagagc gcagggagag ccggagcggc gagctccaag 450

 cctggcatgg acctgcagag acccgattcc taccagggag gagctggccc 500

 tgacttcaac gaccacgtcc tgcataagac catcctggtg ggtgacagtg 550

 gtgtgggaaa gacgtctctg ctggttcagt tcgatcaggg caagttcatc 600

 cccggctcct tctcggccac tgtgggcatc ggattcacga acaaggtggt 650

 gactgtggat ggcgtgagag tgaagctgca gatctgggac accgctgggc 700

 aggaacggtt ccgaagcgtc acccatgctt attacagaga tgctcaggcc 750

 ttgcttctgc tgtatgacat caccaacaaa tcttctttcg acaacatcag 800

 ggcctggctc actgagattc atgagtatgc ccagagggac gtggtgatca 850

 tgctgctagg caacaaggcg gatatgagca gcgaaagagt gatccgttcc 900

 gaagacggag agaccttggc cagggagtac ggtgttccct tcctggagac 950

 cagcgccaag actggcatga atgtggagtt agcctttctg gccatcgcca 1000

 aggaactgaa ataccgggcc gggcatcagg cggatgagcc cagcttccag 1050

 atccgagact atgtagagtc ccagaagaag cgctccagct gctgctcctt 1100

 catgtgaatc ccagggggca gagaggaggc tctggaggca cacaggatgc 1150

 agccttcccc cacccatgcc ctttccttta acttctcaaa cagataccag 1200

 ggcctaaact gctttacctc ccctcctact gagtcaggtt aggtggtggg 1250

 aggtcaccca tttccgagtt aaaccaatgc aatatgagta aaacaaagtc 1300

 atgtgggtat gtctggggta gagagagggg tagcaagttc atgtgtcctc 1350

 cttggtcaca tatctcccaa agctctgatc cctgccatgg gaagtggaca 1400

 ggaaacatga ggtcatgacc tgcaggcatc tttactgcag ctctgccggc 1450

 ctggaggggg agagggggag gaagaagtat gcgctgcaca tttctgaggc 1500

 tactgcattt gctttcaagg cagaaatctt gctctgagca gtcagcggct 1550

 ccagtttggg cccgataagg aagttctccg tggcctccct caggcagagc 1600

 agggaggagg ctgacattgc cagtctcttc tggggcccaa ggcaggttgc 1650

 aggagatcca atcccataga cagctctggg cctcttgcat ttgagttttt 1700

 cagaattaaa ctgcagtatt ttggaaagca aaaaaaaaaa aaaaa 1745

<210> 4619
<211> 216
<212> PRT
<213> Homo sapien

<400> 4619
 Met Asp Leu Gln Arg Pro Asp Ser Tyr Gln Gly Gly Ala Gly Pro
   1               5                  10                  15

 Asp Phe Asn Asp His Val Leu His Lys Thr Ile Leu Val Gly Asp
                  20                  25                  30

 Ser Gly Val Gly Lys Thr Ser Leu Leu Val Gln Phe Asp Gln Gly
                  35                  40                  45

 Lys Phe Ile Pro Gly Ser Phe Ser Ala Thr Val Gly Ile Gly Phe
                  50                  55                  60

 Thr Asn Lys Val Val Thr Val Asp Gly Val Arg Val Lys Leu Gln
                  65                  70                  75

 Ile Trp Asp Thr Ala Gly Gln Glu Arg Phe Arg Ser Val Thr His
                  80                  85                  90

 Ala Tyr Tyr Arg Asp Ala Gln Ala Leu Leu Leu Leu Tyr Asp Ile
                  95                 100                 105

 Thr Asn Lys Ser Ser Phe Asp Asn Ile Arg Ala Trp Leu Thr Glu
                 110                 115                 120

 Ile His Glu Tyr Ala Gln Arg Asp Val Val Ile Met Leu Leu Gly
                 125                 130                 135

 Asn Lys Ala Asp Met Ser Ser Glu Arg Val Ile Arg Ser Glu Asp
                 140                 145                 150

 Gly Glu Thr Leu Ala Arg Glu Tyr Gly Val Pro Phe Leu Glu Thr
                 155                 160                 165

 Ser Ala Lys Thr Gly Met Asn Val Glu Leu Ala Phe Leu Ala Ile
                 170                 175                 180

 Ala Lys Glu Leu Lys Tyr Arg Ala Gly His Gln Ala Asp Glu Pro
                 185                 190                 195

 Ser Phe Gln Ile Arg Asp Tyr Val Glu Ser Gln Lys Lys Arg Ser
                 200                 205                 210

 Ser Cys Cys Ser Phe Met
                 215

<210> 4620
<211> 5458
<212> DNA
<213> Homo sapien

<400> 4620
 cggatgggtg atgtggtcga gaagagtttg gaagggcccc tggcaccttc 50

 tacagatgag ccctcccaga aaacaggaga cttggtcgag atcttaaatg 100

 gggaaaaggt caaatttgac gacgcgggac tctccttaat tcttcagaat 150

 ggcctggaaa ccctgcgaat ggaaaacgct ctgacagatg tcatcttgtg 200

 tgtggacatt caggaattct cctgccaccg cgtggtgctt gccgcagcca 250

 gcaactattt cagggccatg ttctgcaacg atttaaagga aaagtatgag 300

 aaaaggatca ttattaaagg ggttgatgct gagaccatgc acactctgtt 350

 ggactacacg tacaccagca aggcgctgat caccaagcag aatgtccagc 400

 gggtcctgga ggctgctaac ctcttccagt tcctgcggat ggtggatgcc 450

 tgtgccagct tcctcactga agccttgaac ccagaaaact gcgttggaat 500

 actgaggctg gctgacacac actcgctgga cagtctaaag aagcaggttc 550

 agagttacat cattcaaaac tttgtgcaga ttctgaactc tgaggagttt 600

 cttgacctgc ccgtggacac tctgcaccac atcttgaaga gtgatgacct 650

 ttacgtgacc gaggaggctc aggtgtttga gaccgtgatg agctgggtcc 700

 ggcacaagcc atcagaacga ctctgcttac tcccctatgt cctcgagaac 750

 gtgcgcttac cgcttctgga cccgtggtac tttgtggaga cggtggaagc 800

 agatcctctc atcaggcagt gcccagaggt cttcccgctg ctccaggaag 850

 ccaggatgta ccacctttct ggcaatgaga tcatttcgga acgcaccaag 900

 cccaggatgc atgagttcca gtctgaggtg ttcatgatca ttggcggctg 950

 cacgaaggat gaacggtttg tggcagaggt gacctgcctg gaccccctga 1000

 ggcgcagccg cctggaggtg gccaagctcc cgctaacaga gcatgagctg 1050

 gagagtggga ataagaagtg ggtggagttt gcatgcgtga cattgaaaaa 1100

 tgaggtctac atctcaggtg gcaaagaaac acagcatgat gtttggaaat 1150

 ataattcttc gatcaacaag tggattcaga ttgagtattt aaacataggc 1200

 cgctggaggc ataagatggt ggtgttgggt ggcaaggtct atgtgatcgg 1250

 aggctttgac ggcttacaga gaatcaacaa tgtggagacc tacgacccct 1300

 ttcacaactg ctggtcagag gccgcacccc tccttgtcca tgtcagttcc 1350

 tttgcagcca ccagccataa gaagaagctg tatgtgatcg ggggagggcc 1400

 caatgggaaa ctggccacag acaagactca gtgttatgac ccttccacca 1450

 acaagtggag tttgaaggcg gccatgcccg tggaggctaa atgcatcaat 1500

 gcagtgagtt tccgggaccg catctatgtc gttggtgggg ccatgagagc 1550

 gctgtacgcc tacagcccgc tggaagacag ctggtgcctg gtgacccagc 1600

 tcagccacga gcgggccagc tgcggtatcg cgccctgcaa caaccggctc 1650

 tacatcaccg gcgggcggga cgagaagaac gaggttatcg ccacggtgct 1700

 gtgctgggac cccgaggccc agaaactgac agaggagtgc gtcctgcccc 1750

 ggggcgtgtc gcaccacggc agcgtcacca tcaggaagtc gtacacccac 1800

 atccgcagga tcgtgcccgg agcagtgtct gtctgacggc aggatgggga 1850

 gctggagagc ccccccgacc ctcagcgtac ccgcctcacc tctcaccctc 1900

 ctccagtccc acttcaggca gcaggctcga gtttgaggcc atacatcagg 1950

 ggatcccctt gactcacttt gggggaacct tggaagtcac agtttggggt 2000

 cacttgagac cggccaggaa tgtttgcatg acctacctca ggaggggagg 2050

 cgaggaagag taatatttag cattcaggac ccacccaccc tatgccggct 2100

 tctgtgccag gcacttcctt ttatcggttc atttaacctg gtgactggct 2150

 cttatcactt ctagtttaca ggtgagggaa ccaagtttca cagaggctaa 2200

 gtggcgtgcc cctgatcact cagatagcaa gtagctaccc caggagtcta 2250

 aaatccaggt ctttcatctc cgaagtcaat gctctttcca ccatgctgcc 2300

 tatctcagag caggaaaaac aaacaaaaaa caacaacaaa acctggctcg 2350

 tgctgggcgt ggcggctcac gcctgtaatc ccagccctat gggaggctgg 2400

 tcttgaacgc ctgaccttgt gatctgcccg cctcggtctc ccgaagtgct 2450

 gggattacag gtgtgagcca ctgggcccgg tctttttttt ttaaatgatc 2500

 ataagatggc ccattttgga ccggaactgt cattgccaga cagaattgta 2550

 cctttagcac attctggtgc cctggcctct tagtgttcac cagttgtact 2600

 gcaatataga caagatgtct ctagagactc aaactactgt tttattaaaa 2650

 aagtaaacac ctgagcacag ctggcctaca caggagcgac agattctcct 2700

 tgatggtaca ctttctagtt tttacacagt gatttaggtc cacgttcctg 2750

 ataccccatc ctcctgaagc cttcgttttc aagactttta aaaagcactt 2800

 ctacttggtt ttttgatcag tgtagctcaa ttgtgactta aagaacagaa 2850

 tctgtccttc actgtaagag ctacagcttt caaatgagct cactggaaat 2900

 tcattctaat ccccaagctg gagaaacagg ttaagagatc acttgtttca 2950

 tatgctgtat ttaaaaagca acaatgataa caacatagta actgcgttac 3000

 ccaatggact ttattttcat catatgattt caattctctt tatagagttt 3050

 tatttcatat ccggtgtggc ttgttctttt cagcagtttg ggaagttagt 3100

 tattagagtt gatagtgaat tgaattttca ttaaacagtc acggttagaa 3150

 gaagctaata tttgaaacag attttaaaaa cttgaaaaat tacaggtgag 3200

 atttctgttt atgccagatt attgaagata aatataaatg tatgttggtg 3250

 tgtgaaatgc tctgtgcctt agaagcgtga cagttcagct ctctgctgtg 3300

 gaaagtaaca cagggcaata gaaacatatt tgtggaattt tagaacaaac 3350

 tattgctgac tcatgagcac tataataacc atcaggaagc tcccaactga 3400

 agcaatgtaa cagtgtaatc tagttcaatt cagcaagcat tcatggagtt 3450

 cttcatgtct gtcaagcctt gaggacaccc acgaatggca aatctccact 3500

 gctagacact caatacaggt aaataggcca ccagttaata ttcttgtttt 3550

 tattttcttc aagttagcta aaaatgagat gcgtatgaag tgaggaggct 3600

 ggatccaagt cttgattgcc tttcaggggt caaggtggta agctgtgcag 3650

 tgaagtcaac cagtggccat ggcttacatg tttgtctctt tgagatcgcc 3700

 accagaacca tttgtgaact gatttgtgaa ggaaaagtca gtcttactcc 3750

 aaagactatt gcagggagga acttccagag aggaaatcca atgacaatgg 3800

 tactggcata cacagggagc ctcccttcaa aaagacagcg cccctagtca 3850

 gggaggggat ggcggtcctt tgataagacc cataggcaaa cttcgagccc 3900

 atcagcaggt caaccctatg ctgggaaagt gaggatttgg gatttctgtg 3950

 ctataaacct gattctaaat gtaggaccca agtttctgga ctacttcaga 4000

 atacctaaat gaatcatgga aacactcttt atgatttttt acaacaccag 4050

 atatgcaggt gaattgtgga aaatgtcatg tagctgacac tcaagaaata 4100

 gggattccta ataatgacat gggtagggaa cagatacacc tggttagaag 4150

 gtctagggtt ctgtatatga agctgccagt ctgtagctct tcgagaaaga 4200

 aagttcaagt catttggggg aaacttaaga atagtcatca gggttttagc 4250

 ttctaggcac cagccaagga tgagaacttc taaaatctaa aatccatttc 4300

 aagaaataaa gacgaacaca tttgcaggaa ggtaactgtt ataacccaca 4350

 ccatcagcag ggggaaagcc aagctgagaa taaacccaga gacaaagaac 4400

 cctcggactc aggcaggaca tggcaggatg ttctggcaca gcagactgga 4450

 gactgaggca gggcctgtga gtggacagag cacccctggc tgggaagaag 4500

 aagatggggt aggaggaggt caggttccaa ggatgcaggt ctggaaaatg 4550

 atatcggagg ccctggagtt tgtgagcttg gctctagtcc caagaagggt 4600

 gagggagaat aagggtaagg gagtattcta ggcaaggaac taaggaagga 4650

 atccccttct tagagcagag gcacaagtta gagcaggccc agcatttggg 4700

 ccaacttact gtggggcctc tgagctgctc agctgggtct cctgtcctag 4750

 agggaaggtg gcccagagtc tttggtggag cggaatctgt agatgaggaa 4800

 gggactccag ttgccaaggt tgatctgaaa caggcaggga gctaagctca 4850

 tcagaacacc aacagattca tgttctcgtc ttagctttca tctattctgg 4900

 tctcaatggc ttcgggaaac acacatatac acatacacca tgcccttgaa 4950

 ctcaaagcaa actacgctct cagggaaata caaatatcac gttcttatag 5000

 ctgtaaagta tagcttagct atttatagaa gactatgagg tactgttgtg 5050

 agttatttgc ttatcctgtt ttattctgaa aaatgaaagt gctcaataga 5100

 atttttaacg ttggcaacac cataaggatt tcttatgtta agtcccaact 5150

 tggggttgca aaatcatttt ttcccttaat acctgggtgt tgtattagat 5200

 ctcataattt gacaagttaa ccttttagaa atccacatat atctcaaatc 5250

 tggctactgc aaaaccagtt ttgacaggtc agattttcat atgtataggt 5300

 ataaatagcc aacactcagt gaacaaaatc ctttaagcat tttggttaca 5350

 taaagttgta tgttttaagt gatcaaacta agaatattgt ttataggttt 5400

 taaaaaccaa accaataaaa tttttattta ttcaataaaa tatgcacaga 5450

 acagaaag 5458

<210> 4621
<211> 610
<212> PRT
<213> Homo sapien

<400> 4621
 Met Gly Asp Val Val Glu Lys Ser Leu Glu Gly Pro Leu Ala Pro
   1               5                  10                  15

 Ser Thr Asp Glu Pro Ser Gln Lys Thr Gly Asp Leu Val Glu Ile
                  20                  25                  30

 Leu Asn Gly Glu Lys Val Lys Phe Asp Asp Ala Gly Leu Ser Leu
                  35                  40                  45

 Ile Leu Gln Asn Gly Leu Glu Thr Leu Arg Met Glu Asn Ala Leu
                  50                  55                  60

 Thr Asp Val Ile Leu Cys Val Asp Ile Gln Glu Phe Ser Cys His
                  65                  70                  75

 Arg Val Val Leu Ala Ala Ala Ser Asn Tyr Phe Arg Ala Met Phe
                  80                  85                  90

 Cys Asn Asp Leu Lys Glu Lys Tyr Glu Lys Arg Ile Ile Ile Lys
                  95                 100                 105

 Gly Val Asp Ala Glu Thr Met His Thr Leu Leu Asp Tyr Thr Tyr
                 110                 115                 120

 Thr Ser Lys Ala Leu Ile Thr Lys Gln Asn Val Gln Arg Val Leu
                 125                 130                 135

 Glu Ala Ala Asn Leu Phe Gln Phe Leu Arg Met Val Asp Ala Cys
                 140                 145                 150

 Ala Ser Phe Leu Thr Glu Ala Leu Asn Pro Glu Asn Cys Val Gly
                 155                 160                 165

 Ile Leu Arg Leu Ala Asp Thr His Ser Leu Asp Ser Leu Lys Lys
                 170                 175                 180

 Gln Val Gln Ser Tyr Ile Ile Gln Asn Phe Val Gln Ile Leu Asn
                 185                 190                 195

 Ser Glu Glu Phe Leu Asp Leu Pro Val Asp Thr Leu His His Ile
                 200                 205                 210

 Leu Lys Ser Asp Asp Leu Tyr Val Thr Glu Glu Ala Gln Val Phe
                 215                 220                 225

 Glu Thr Val Met Ser Trp Val Arg His Lys Pro Ser Glu Arg Leu
                 230                 235                 240

 Cys Leu Leu Pro Tyr Val Leu Glu Asn Val Arg Leu Pro Leu Leu
                 245                 250                 255

 Asp Pro Trp Tyr Phe Val Glu Thr Val Glu Ala Asp Pro Leu Ile
                 260                 265                 270

 Arg Gln Cys Pro Glu Val Phe Pro Leu Leu Gln Glu Ala Arg Met
                 275                 280                 285

 Tyr His Leu Ser Gly Asn Glu Ile Ile Ser Glu Arg Thr Lys Pro
                 290                 295                 300

 Arg Met His Glu Phe Gln Ser Glu Val Phe Met Ile Ile Gly Gly
                 305                 310                 315

 Cys Thr Lys Asp Glu Arg Phe Val Ala Glu Val Thr Cys Leu Asp
                 320                 325                 330

 Pro Leu Arg Arg Ser Arg Leu Glu Val Ala Lys Leu Pro Leu Thr
                 335                 340                 345

 Glu His Glu Leu Glu Ser Gly Asn Lys Lys Trp Val Glu Phe Ala
                 350                 355                 360

 Cys Val Thr Leu Lys Asn Glu Val Tyr Ile Ser Gly Gly Lys Glu
                 365                 370                 375

 Thr Gln His Asp Val Trp Lys Tyr Asn Ser Ser Ile Asn Lys Trp
                 380                 385                 390

 Ile Gln Ile Glu Tyr Leu Asn Ile Gly Arg Trp Arg His Lys Met
                 395                 400                 405

 Val Val Leu Gly Gly Lys Val Tyr Val Ile Gly Gly Phe Asp Gly
                 410                 415                 420

 Leu Gln Arg Ile Asn Asn Val Glu Thr Tyr Asp Pro Phe His Asn
                 425                 430                 435

 Cys Trp Ser Glu Ala Ala Pro Leu Leu Val His Val Ser Ser Phe
                 440                 445                 450

 Ala Ala Thr Ser His Lys Lys Lys Leu Tyr Val Ile Gly Gly Gly
                 455                 460                 465

 Pro Asn Gly Lys Leu Ala Thr Asp Lys Thr Gln Cys Tyr Asp Pro
                 470                 475                 480

 Ser Thr Asn Lys Trp Ser Leu Lys Ala Ala Met Pro Val Glu Ala
                 485                 490                 495

 Lys Cys Ile Asn Ala Val Ser Phe Arg Asp Arg Ile Tyr Val Val
                 500                 505                 510

 Gly Gly Ala Met Arg Ala Leu Tyr Ala Tyr Ser Pro Leu Glu Asp
                 515                 520                 525

 Ser Trp Cys Leu Val Thr Gln Leu Ser His Glu Arg Ala Ser Cys
                 530                 535                 540

 Gly Ile Ala Pro Cys Asn Asn Arg Leu Tyr Ile Thr Gly Gly Arg
                 545                 550                 555

 Asp Glu Lys Asn Glu Val Ile Ala Thr Val Leu Cys Trp Asp Pro
                 560                 565                 570

 Glu Ala Gln Lys Leu Thr Glu Glu Cys Val Leu Pro Arg Gly Val
                 575                 580                 585

 Ser His His Gly Ser Val Thr Ile Arg Lys Ser Tyr Thr His Ile
                 590                 595                 600

 Arg Arg Ile Val Pro Gly Ala Val Ser Val
                 605                 610

<210> 4622
<211> 3365
<212> DNA
<213> Homo sapien

<400> 4622
 gaggagaggg gctggctctc agtccccgaa tcgcgtgggg tgcctccacc 50

 ccctgcgatg ggggtcccta gagccagggg gggaagaggg gctggctctc 100

 agtctgcgcc tcgcggagga tgcctccccc acttgcaatg tgagtcctaa 150

 gagccagagg tgggaggggc tggctctcag ttcccgcctc gcggtgtgtg 200

 cctgccccgc tgcgatggag gtcctaagag caaggggggg aagaggggct 250

 ggctctggta gattgcaaat gacctgcttt ttttctgatc ccgagctgcg 300

 ttcggacccc tgtcggatag taaatcccag gtaaggtacc tgcggtcggc 350

 aggtctgagc tttcttcttg gacacctaaa acccacagtc ctccaggtgg 400

 gtgctaagga tcttagaatc cgcggtgggg gtcctaagcc agcgggggaa 450

 gaggggctgg ctctcagtcc ccgactcgtg ggcggtgtct tccccccttg 500

 cgatggggat cctaagagcc agggggggaa gaggggcggg ctctcagtgc 550

 ccgcctcgct ggaagtgcct cccacccatg agatgggtgt cctaagagcc 600

 aaggggggga ataggggcag gctctcgatc cccgcctctc ggggggtgcc 650

 tccccccctt gcgatcgggg tcccaagggc caggggggga agaggggctg 700

 gctctcagtc cccgtctctc gggtggtgcc tcccgccact acgatgtggg 750

 tcctaagagc cgggggtggg agggtctggc tctcagtcac cgcctcgtga 800

 ggagtgcctc ccccgctgcg atggaagttc taagacacag ggggggaaga 850

 ggttctggct ctcagtcccc gcctcgcggg gggtgccacg cgcctgcatt 900

 gggggtccta agagccatgg gggggtagag gggctggctc tcagtccccg 950

 cctcgtgggg ggtgcttccc cccccgcgat ggggtaccta agagcgggtg 1000

 ggggggggga agaggggctg gttctcagtc cccgcctcgc gggggttgcc 1050

 cccccctgcg atgggggtct caagagcctg ggggggaaga ggggctggct 1100

 ctcagtcccc gcctctccgg ggtgcgtccc ccccctgcaa tgggggtcct 1150

 aagagtcagg gggagtgagc ggctggctct cagtccccgc ctcgcagggg 1200

 gtgcctcccc cgcctgcgat gggggtccga agagcctggg ggggaagaga 1250

 ggcaggctct cagtccccgc ttcgcggggg gtgcctcccc gcacagcgat 1300

 gggggtccca agagccaggg gggaagtggg gctggctctc agttcccgcc 1350

 ttgcggtgtg tgcctccccc cctgcgatgg gggtcctaag agccagggga 1400

 tgaaaagggg ctggctctca gtcctcgcct ggcgggagtg cctccccccc 1450

 cgcgatgggg gtcctaagat cctggggggg aagaggagct ctctctcagt 1500

 ccccgcctcg cggggggtgc ctccgactcc tgcgatgggg gtcctaagag 1550

 ccaggggggt aagaggggca ggctctcagt ccccgcctcg ctgcgggtgc 1600

 ctccgcccct gcgatggggg tcctaagaac cagggaggga agaggggctg 1650

 gttctcagtc ctcgcctcgc ggggagtgcc tccctccact gcgatggggg 1700

 tcccaggagc caggggggaa gtggggctgg ctctcagttc ccgcctcacg 1750

 aggggtgcct ccccccactg cgatggggga cctaagagca agcgagggga 1800

 agacgggctg gctccggtag attgtaaatg acctgctttc tttcttttcc 1850

 cgggctgcgt tcggacccct gtcgattgta aatcccaagt aaggtacctg 1900

 ccgtgggcag atctgagctt tcttcttgga caccccatac ccacagtcct 1950

 ccaggccacc cttaagtaca atgttctcct acctaagaag gcatctggat 2000

 tttctctttc cttggaaata gtaaagaact actctttgac tgtttttgac 2050

 ctcacagtga acctcaaata cactggaatt cgcaataaat ccagtatggt 2100

 ggttatagat gtaaaaatgc tatcaggatt tactccaacc atgtcatcca 2150

 ttgaagagct tgaaaacaag ggccaagtga tgaagactga agtcaagaat 2200

 gaccatgttc ttttctactt ggaaaatgtt tttggtcgag cagacagttt 2250

 cactttttct gctgagcaga gcaaccttgt gttcaacatt cagccagccc 2300

 caggcatggt ctacgattag tacgaaaaag gtaggcaagc tacttctgtg 2350

 gactttgact taaaaagagg agtggggaat attctgaaat gttaacttaa 2400

 aaatttgata gattaatttc taaaacatat actaaaatgt tgtagagacc 2450

 atacaactgt tccctggaag gttggtacta tttatttctt gttgaatgct 2500

 gtgtgaagtt tgtggagtgt ttgaattctg tctctatcat ttactaatag 2550

 aatatatttc atcaagtgtc ttaaatatta ttagcatatt tctgcataat 2600

 gtataaaatg ggaaagtaat tgtctctatt tcaaaattat tggaaggatt 2650

 agatctaatg tgcttatatc atctatttaa taaaaataca tgttcccttt 2700

 attttttcag aagaatatgc cctagctttt taccacatca acagtagttc 2750

 agtttccgag tgagacaaag caattactgg aagaagtaaa gaaattttat 2800

 tacgtcataa accattgaaa acacatctag taagaaaatg aaaacctgaa 2850

 taagatagga caatagttga agaaagaaaa gtctctggta cttcattaga 2900

 cttgtgtagc tgtgtactgc atgagtaatc tgataatcat taagattata 2950

 ttaatttctt taaaaatagc tttaaagaat tcacagctat atatgtacct 3000

 tttataaatc tctcattttt gttttgtaag ttgacaggtc agtaaaaatt 3050

 taggcatata tatttgtaca tatgtgtgta tatgtatata catgtctatg 3100

 tgcctatata tgcatgtttt tatttctaaa tatctattta tatatacata 3150

 caaatgtgtt tattgtttaa atgatgtttt aaatcccagg tggagaagca 3200

 tttcttttaa caaactgatt cttctgtatc aaacctggaa aaaaatcatg 3250

 aaccatctga catcgtgaac agtctgcagt gggctatggt ttcttgacaa 3300

 gtcttatttc cttatcatcc cattaaatgt tgtcattttg aaaaaaaaaa 3350

 aaaaaaaaaa aaaag 3365

<210> 4623
<211> 143
<212> PRT
<213> Homo sapien

<400> 4623
 Met Lys Arg Gly Trp Leu Ser Val Leu Ala Trp Arg Glu Cys Leu
   1               5                  10                  15

 Pro Pro Arg Asp Gly Gly Pro Lys Ile Leu Gly Gly Lys Arg Ser
                  20                  25                  30

 Ser Leu Ser Val Pro Ala Ser Arg Gly Val Pro Pro Thr Pro Ala
                  35                  40                  45

 Met Gly Val Leu Arg Ala Arg Gly Val Arg Gly Ala Gly Ser Gln
                  50                  55                  60

 Ser Pro Pro Arg Cys Gly Cys Leu Arg Pro Cys Asp Gly Gly Pro
                  65                  70                  75

 Lys Asn Gln Gly Gly Lys Arg Gly Trp Phe Ser Val Leu Ala Ser
                  80                  85                  90

 Arg Gly Val Pro Pro Ser Thr Ala Met Gly Val Pro Gly Ala Arg
                  95                 100                 105

 Gly Glu Val Gly Leu Ala Leu Ser Ser Arg Leu Thr Arg Gly Ala
                 110                 115                 120

 Ser Pro His Cys Asp Gly Gly Pro Lys Ser Lys Arg Gly Glu Asp
                 125                 130                 135

 Gly Leu Ala Pro Val Asp Cys Lys
                 140

<210> 4624
<211> 2616
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2080, 2156, 2215, 2270
<223> Unknown base

<400> 4624
 ctttatggcg tgggagaggc cacagcccgg actccatcga ctcccccggc 50

 tcttagacta aaatcatgcc caagttcaaa caacgaagac gaaagctaaa 100

 agccaaagcc gaaagattat tcaaaaaaaa agaagcctct cactttcagt 150

 ccaagctaat tacacctcct cctccaccac cctcaccaga aagagtcggt 200

 atttcttcaa tagatatatc tcaaagcaga agctggctaa catcatcctg 250

 gaacttcaat tttcctaaca tcagagatgc aataaaactt tggacaaata 300

 gagtatggtc tatatacagc tggtgccaga actgcataac ccagagttta 350

 gaagtattga aagacaccat ctttccatct cgtatctgcc accgagaact 400

 ttacagtgta aaacaacagt tttgcatttt ggaaagtaaa ttatgcaagc 450

 ttcaggaagc actgaagacc atctcagaaa gttcttcctg tccaagctgt 500

 ggtcaaacat gtcacatgag tggtaaactt acaaatgtgc ctgcctgcgt 550

 tctgatcacc cctggagact ccaaagctgt gcttcctccc acactgccac 600

 agccagccag ccattttcct cctcctcctc cacctccacc tctgccacct 650

 cctccaccac cactagcacc tgtgttgctc agaaaaccca gtctcgctaa 700

 agcacttcag gctggaccat taaaaaaaga tggacccatg cagataacag 750

 ttaaagatct gctgactgta aaattaaaga agacacagag tttagatgaa 800

 aagaggaagc ttataccatc gccgaaagca cggaatccac tagttaccgt 850

 ctctgacttg cagcatgtta ccctgaaacc taactccaaa gtgttatcga 900

 ctcgagttac aaacgtctta atcactcctg gaaaaagtca gatggatctg 950

 cggaaactgc ttagaaaagt cgatgtagag aggaggccag gtggaacccc 1000

 tcttaccaat aaggaaaata tggaaacagg aacaggactg actccagtga 1050

 tgacgcaggc cttaaggaga aagtttcagc tggctcaccc tagaagccca 1100

 actccaactc tgccactttc tacaagcagc tttgatgaac aaaactgatg 1150

 ccaactctgc ctcactccat gagatgatcc ataacaaata cagataaaaa 1200

 cacccagctg ggtgcagtgg ctcgcacctg taatcccagc actttgggag 1250

 gctgaggcag gtggatcacc tgaggtcggg agtttgagac cagcctggcc 1300

 aacatggtga aatcccatct ctactgaaaa tacagaattg gccgggtgtg 1350

 gtgtcacgcg cctgtggtcc cagttacttg aacctgggag gcggaggttg 1400

 cagtgagccg agattgcaac actgccactc cagcctgggt gacagagcaa 1450

 gagaccctgt ctcaaaaaaa aaaaaaaaaa aattaaatgg gtagtgacgt 1500

 taagagatat atatcagctt ctagtaaaag tttttttttt taaacctgct 1550

 agctacattt acattatgta aaaataaatg gaataatcac tgagaataaa 1600

 gcagttgagt atttataaca ataatatttt atggggcgct tataatgttt 1650

 ataatattgt aaaccactgt gtactctatt catttaatgc taaatgactt 1700

 gaccattctt gtgggataag agatcattaa aaaaatgcta gggccgggca 1750

 ccatggctca cgcctgtaat cccaggactt taggaggcca aggcaggtgg 1800

 atgacttgag ctcaggagtt tgagaccagc ctgggcaaca tgatgaaaac 1850

 tccgtctcta ccaaaaatca aaaaaattag ccaggtgtga tgttgtgcgc 1900

 ctgtagtccc agctacttgt gaggctgagg tgggaggatg gtttgggccc 1950

 cggaggtaga ggttgcagtg agctgagatt gtgccactgt attccatcct 2000

 gggcaacaga gccagaccct gcctcaaaaa aaaaaaaaaa aaaaaaaagg 2050

 cctggctttg ctacataatg aggccaggcn aaaaaaaaaa agtcctgtgg 2100

 aaatcatata gacaaacatt tgcaaagctg ctactgccat tgtaccagtg 2150

 ttaaantgtg ttctaccttg catcttttac tgatttttat gacagatttt 2200

 atattgtaac cattngagaa ctctgtaagt gctatggctt ccttaaacta 2250

 cgatttatca tatgctcccn gtgtttactt tgagactgaa tggcaaccag 2300

 agaatgtaaa caaccaaggt gcatctggtt atgtttgcac agtggctcac 2350

 gcctgtaatc ccagcacttt gggaggctga ggcgggcaaa acacttgagg 2400

 tcagacgttt gagaccagcc tggccaacat ggtgaaaccc cgtctctacc 2450

 aaaaataaaa ataaaaatta tccaggcgtg gtggcatgtg cctatagccc 2500

 cagctactca ggaagctaga gcacgagaat tatgtgcatc ctggaggtga 2550

 aggttgcagt gagccaagat cacaccactc cactccagtc tggacaacag 2600

 agtgagaccc tgtgtc 2616

<210> 4625
<211> 360
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2080, 2156, 2215, 2270
<223> Unknown amino acid

<400> 4625
 Met Pro Lys Phe Lys Gln Arg Arg Arg Lys Leu Lys Ala Lys Ala
   1               5                  10                  15

 Glu Arg Leu Phe Lys Lys Lys Glu Ala Ser His Phe Gln Ser Lys
                  20                  25                  30

 Leu Ile Thr Pro Pro Pro Pro Pro Pro Ser Pro Glu Arg Val Gly
                  35                  40                  45

 Ile Ser Ser Ile Asp Ile Ser Gln Ser Arg Ser Trp Leu Thr Ser
                  50                  55                  60

 Ser Trp Asn Phe Asn Phe Pro Asn Ile Arg Asp Ala Ile Lys Leu
                  65                  70                  75

 Trp Thr Asn Arg Val Trp Ser Ile Tyr Ser Trp Cys Gln Asn Cys
                  80                  85                  90

 Ile Thr Gln Ser Leu Glu Val Leu Lys Asp Thr Ile Phe Pro Ser
                  95                 100                 105

 Arg Ile Cys His Arg Glu Leu Tyr Ser Val Lys Gln Gln Phe Cys
                 110                 115                 120

 Ile Leu Glu Ser Lys Leu Cys Lys Leu Gln Glu Ala Leu Lys Thr
                 125                 130                 135

 Ile Ser Glu Ser Ser Ser Cys Pro Ser Cys Gly Gln Thr Cys His
                 140                 145                 150

 Met Ser Gly Lys Leu Thr Asn Val Pro Ala Cys Val Leu Ile Thr
                 155                 160                 165

 Pro Gly Asp Ser Lys Ala Val Leu Pro Pro Thr Leu Pro Gln Pro
                 170                 175                 180

 Ala Ser His Phe Pro Pro Pro Pro Pro Pro Pro Pro Leu Pro Pro
                 185                 190                 195

 Pro Pro Pro Pro Leu Ala Pro Val Leu Leu Arg Lys Pro Ser Leu
                 200                 205                 210

 Ala Lys Ala Leu Gln Ala Gly Pro Leu Lys Lys Asp Gly Pro Met
                 215                 220                 225

 Gln Ile Thr Val Lys Asp Leu Leu Thr Val Lys Leu Lys Lys Thr
                 230                 235                 240

 Gln Ser Leu Asp Glu Lys Arg Lys Leu Ile Pro Ser Pro Lys Ala
                 245                 250                 255

 Arg Asn Pro Leu Val Thr Val Ser Asp Leu Gln His Val Thr Leu
                 260                 265                 270

 Lys Pro Asn Ser Lys Val Leu Ser Thr Arg Val Thr Asn Val Leu
                 275                 280                 285

 Ile Thr Pro Gly Lys Ser Gln Met Asp Leu Arg Lys Leu Leu Arg
                 290                 295                 300

 Lys Val Asp Val Glu Arg Arg Pro Gly Gly Thr Pro Leu Thr Asn
                 305                 310                 315

 Lys Glu Asn Met Glu Thr Gly Thr Gly Leu Thr Pro Val Met Thr
                 320                 325                 330

 Gln Ala Leu Arg Arg Lys Phe Gln Leu Ala His Pro Arg Ser Pro
                 335                 340                 345

 Thr Pro Thr Leu Pro Leu Ser Thr Ser Ser Phe Asp Glu Gln Asn
                 350                 355                 360

<210> 4626
<211> 1292
<212> DNA
<213> Homo sapien

<400> 4626
 ggacgtgact gggaggagcc tgcccgcccc ggctcgctgc gccgcgcgca 50

 cagggcccgc gccagcgacc atggcggagc ccacagtgtg ctccttcctc 100

 accaaggtgc tgtgcgccca cggcggccgc atgttcctga aggacctgcg 150

 cggccacgtg gagctgtcgg aggccaggct ccgggacgtg ctgcagcgcg 200

 ccgggcccga gcgtttcctg ctgcaggagg tggagacgca ggagggcctc 250

 ggggacgcgg aggccgaggc ggcggccggc gcggtgggcg gtggcggcac 300

 ctccgcctgg agggtggtgg ccgtgtccgg gactataggt gcatgccacc 350

 atactcagct aatcttttta ggtttttagt agagacaagg tctcactatg 400

 ttgcccaggc tggtcttgaa ctcctaagct caagcagtcc tcccgccttg 450

 gcctctgaat gtgctgggat tacaggcatg agccactatg cctaaccata 500

 ttttttccaa tattaaaaaa tctttttttc cccctaagga atgtgttata 550

 taaggtcaac atgtttttag tgcttcagtt tgacttgtct acatctaaag 600

 ttaactcttt aaggcttaca tttatgatta taattctttc catcgaggga 650

 tttagtctcc attattgtca tgtttcttga tttttttcat tatacttggt 700

 tcttcttttt gtctaggttt tatatatacc ttaattaatt ctttcttggc 750

 tgttttatat ctatgttgct gtcagcatgg gaatctctat tattagaaag 800

 ctattaactt ttaaaatatg tatcttttgg tgattttctt tgttctaaca 850

 gttttagatg gcctgtttgc tctttctaaa tataaaatca taggtatttc 900

 tattttgttt ttgtgtttca taaaattgta ataagttttt ttgatatttt 950

 ttcattacat atgaagttaa ttgttggttt taaacaaatg ttctttgtta 1000

 ggataacaga aataacatct tctattcttg tttgttggaa gctaaaagct 1050

 tgataaaagg aattggtgtc ttttgataca atcaaatttt tatcacttaa 1100

 attgcctaat atgattataa taagggtttt tgtaatatta aaacatcctt 1150

 aaattcctga gataaaactc tacctggtta tagtatatgt tcttttaatg 1200

 tattatcttt cctatttgct gtacatctat acattcataa ataaaattca 1250

 tttatatttt agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1292

<210> 4627
<211> 102
<212> PRT
<213> Homo sapien

<400> 4627
 Met Ala Glu Pro Thr Val Cys Ser Phe Leu Thr Lys Val Leu Cys
   1               5                  10                  15

 Ala His Gly Gly Arg Met Phe Leu Lys Asp Leu Arg Gly His Val
                  20                  25                  30

 Glu Leu Ser Glu Ala Arg Leu Arg Asp Val Leu Gln Arg Ala Gly
                  35                  40                  45

 Pro Glu Arg Phe Leu Leu Gln Glu Val Glu Thr Gln Glu Gly Leu
                  50                  55                  60

 Gly Asp Ala Glu Ala Glu Ala Ala Ala Gly Ala Val Gly Gly Gly
                  65                  70                  75

 Gly Thr Ser Ala Trp Arg Val Val Ala Val Ser Gly Thr Ile Gly
                  80                  85                  90

 Ala Cys His His Thr Gln Leu Ile Phe Leu Gly Phe
                  95                 100

<210> 4628
<211> 3545
<212> DNA
<213> Homo sapien

<400> 4628
 gggagattcg attggaaggc tgccggcgtg ctactgagtt cggccggtcc 50

 gagtcactgt gcgtcgcctg ggcgcgttcc tggtcttctc ccccagggtc 100

 ttgctctgtc acccaggctg gagtgccatg gcatcatcat agctcactat 150

 ggccttgatc ctcctgcctt agcctcccaa gcagctggta ttacagacca 200

 cggtgtgaac acatgaacag aagacgaaaa tttcttctag cctcagtact 250

 tgctctccag aattcaagtt ttatatatcc atcatgtcag aagtgcttct 300

 ctaggataat cctggtctcc aaaaggtcta attgtccaaa atgtggctct 350

 actggtgaat ctggaaatgc caattacaga tacaaacttt ccttaaaagt 400

 tgcagaatca aacaaattgt ttgttattac tgtatttgga agttgcttag 450

 atacattttt tggtcttact gccactggtt tgcacaggta cattcaggat 500

 cctaataaaa ttccagaaac actggacaat gatacaactc agaatctatt 550

 aactaaagca gttgaaactt gctttgttgg acaaagcttt atttttggag 600

 tgacgaattt tgaaaaccaa cctggacaag gttcagatgc cagtaacttc 650

 ttacagcaat gctctgacca caaaagaaaa gccaaagcac tagtggcttg 700

 ccagattgtt ctaccagacc caggtattgc aggctttact gtcattgact 750

 acttccatca acttttgcag acttttaatt tcaggaaact tcagtgtgac 800

 tctcaggcac ctaacaatca cttacttgct ttagatcact caaatagtga 850

 tctcagcagc acatatactt ctgacagcac ttctgatttt ttcaagtcct 900

 gcagcaagga tactttttca aaattctggc agccatcact tgaattcact 950

 tgcattgttt cacaactaac agataatgat gatttttcag cttcagaaca 1000

 aagtaaggcc tttggtactc ttcagcagaa cagaaagtcc atctccattg 1050

 cagaggccac tggttccagt agctgccatg atcccattca ggattcatgg 1100

 agccttgttt catatatgga taaaaagagt acagcagaaa agttgggtaa 1150

 agaacttggc ttacaagcta aggagctgag tgcagttcac agcagtcatc 1200

 atgaaattgg agttaatgac tctaatttat tctctttgga aatgcgagag 1250

 ccccttgagt caagtaatac aaaatccttc cacagtgcag tggaaattaa 1300

 aaataggtcc cagcatgagc taccatgttt tcagcatcat ggtatagata 1350

 ccccaactag ccttcagaag agatctgcat gttgtccacc ttcgttactc 1400

 agacttgaag agacagccag cagttcccag gatggtgacc ctcaaatttg 1450

 ggatgatctg ccattctctg aaagcctgaa caagtttctg gcagttcttg 1500

 aaagtgagat tgctgtaacc caggcagatg tcagtagtag gaaacatcat 1550

 gtagataatg acattgataa atttcatgca gaccacagca gtttatctgt 1600

 gactccccag agaactactg gagccctgca tacaccacct atagctttaa 1650

 gatcatcaca agtaatagtc aaagcaaact gtagcaaaga tgacttcctt 1700

 ttcaactgta aaggaaatct aagtcctagt gttgaaaagg agtcacaacc 1750

 agataacaaa gtagaggctg tctctgtaaa tcataatgga agagatatgt 1800

 cagaatattt tttaccgaat ccttacctgt cagctctgtc ttcatcttca 1850

 aaagatttag aaacaatagt tactcttaag aagactatca gaatctcacc 1900

 acacagggag agtgaccatt ctagtctaaa taacaaatat ttgaatggat 1950

 gtggagaaat atcagtttca gaaatgaatg aaaagttgac aactctgtgt 2000

 tataggaagt ataatgatgt ctctgatctt tgcaaattag aaaataaaca 2050

 atattgtagg tggtccaaga accaagatga cagttttaca atttgcagga 2100

 aacttacata tcctttagaa actctttgca atagtccaaa tagaagtaca 2150

 aatacattga aagaaatgcc ttggggacat atcaataaca acgtaacaca 2200

 gagctattct attggttatg aaggtagcta tgatgcctct gctgatctct 2250

 ttgatgatat tgctaaagaa atggacattg caactgagat taccaaaaaa 2300

 tcacaggata ttttgttaaa atggggaaca tctttggcag aaagtcaccc 2350

 ttcagagtct gatttttcac tgagatcact ttctgaagac ttcatccagc 2400

 cttcacaaaa attatccttg caaagcctat ctgactctag gcattcaaga 2450

 acatgctctc caacacctca ttttcaatca gattcagaat ataattttga 2500

 aaatagtcaa gactttgttc catgttcaca gtcaactcca atttcagggt 2550

 tccaccaaac aagaattcat gggataaaca gagctttcaa aaaacctgta 2600

 ttttattcag atcttgatgg taactatgaa aaaataagga ttttccctga 2650

 aaatgacaaa cagcaagcca gcccaagctg tccaaaaaat ataaaaacac 2700

 ctagccagaa aatcagaagc cctattgtat ctggtatttc acaaccagac 2750

 gttttcaatc actacccttt tgctgagtgc catgaaactg atagtgatga 2800

 atgggtccct cctaccacac aaaaaatatt tccttcagat atgcttggat 2850

 tccaaggcat aggtctaggg aaatgccttg ctgcctatca tttccctgat 2900

 caacaagagt taccaagaaa gaaactgaaa catattagac aaggaaccaa 2950

 taaaggttta attaagaaga aattaaagaa tatgcttgca gcagttgtta 3000

 cgaaaaagaa aactcataaa tataactgta aaagttcagg ctggatttcc 3050

 aaatgtccag acattcaagt cttagcagca cctcagctgc accctattct 3100

 tggacctgat tcttgttcag aagtcaaatg ttgccttcca ttttcagaaa 3150

 aaggcccacc ttcagtgtgt gaaactcgaa gtgcttggtc acctgaattg 3200

 ttttcataaa aagtcacctg aacccaattc ctgaactttt aaatctgttt 3250

 ggaaatgttt gccttcaggg gtacggaaag cattctttac attttgaaca 3300

 cttggagaga agcaaattga aaacaggact ctgctgggag ctactgtgcc 3350

 ttttaaaata taaagccatt gttttcccca gggttttatc tagaatacta 3400

 tgattaggta gttgagcact ttatcttata ctgtttattg tactttaata 3450

 atattgttaa gattgttttt gaaagtatta atgtttgtta aaatcacata 3500

 tacatccaga aataaagact ttgcaaacca aaaaaaaaaa aaaaa 3545

<210> 4629
<211> 998
<212> PRT
<213> Homo sapien

<400> 4629
 Met Asn Arg Arg Arg Lys Phe Leu Leu Ala Ser Val Leu Ala Leu
   1               5                  10                  15

 Gln Asn Ser Ser Phe Ile Tyr Pro Ser Cys Gln Lys Cys Phe Ser
                  20                  25                  30

 Arg Ile Ile Leu Val Ser Lys Arg Ser Asn Cys Pro Lys Cys Gly
                  35                  40                  45

 Ser Thr Gly Glu Ser Gly Asn Ala Asn Tyr Arg Tyr Lys Leu Ser
                  50                  55                  60

 Leu Lys Val Ala Glu Ser Asn Lys Leu Phe Val Ile Thr Val Phe
                  65                  70                  75

 Gly Ser Cys Leu Asp Thr Phe Phe Gly Leu Thr Ala Thr Gly Leu
                  80                  85                  90

 His Arg Tyr Ile Gln Asp Pro Asn Lys Ile Pro Glu Thr Leu Asp
                  95                 100                 105

 Asn Asp Thr Thr Gln Asn Leu Leu Thr Lys Ala Val Glu Thr Cys
                 110                 115                 120

 Phe Val Gly Gln Ser Phe Ile Phe Gly Val Thr Asn Phe Glu Asn
                 125                 130                 135

 Gln Pro Gly Gln Gly Ser Asp Ala Ser Asn Phe Leu Gln Gln Cys
                 140                 145                 150

 Ser Asp His Lys Arg Lys Ala Lys Ala Leu Val Ala Cys Gln Ile
                 155                 160                 165

 Val Leu Pro Asp Pro Gly Ile Ala Gly Phe Thr Val Ile Asp Tyr
                 170                 175                 180

 Phe His Gln Leu Leu Gln Thr Phe Asn Phe Arg Lys Leu Gln Cys
                 185                 190                 195

 Asp Ser Gln Ala Pro Asn Asn His Leu Leu Ala Leu Asp His Ser
                 200                 205                 210

 Asn Ser Asp Leu Ser Ser Thr Tyr Thr Ser Asp Ser Thr Ser Asp
                 215                 220                 225

 Phe Phe Lys Ser Cys Ser Lys Asp Thr Phe Ser Lys Phe Trp Gln
                 230                 235                 240

 Pro Ser Leu Glu Phe Thr Cys Ile Val Ser Gln Leu Thr Asp Asn
                 245                 250                 255

 Asp Asp Phe Ser Ala Ser Glu Gln Ser Lys Ala Phe Gly Thr Leu
                 260                 265                 270

 Gln Gln Asn Arg Lys Ser Ile Ser Ile Ala Glu Ala Thr Gly Ser
                 275                 280                 285

 Ser Ser Cys His Asp Pro Ile Gln Asp Ser Trp Ser Leu Val Ser
                 290                 295                 300

 Tyr Met Asp Lys Lys Ser Thr Ala Glu Lys Leu Gly Lys Glu Leu
                 305                 310                 315

 Gly Leu Gln Ala Lys Glu Leu Ser Ala Val His Ser Ser His His
                 320                 325                 330

 Glu Ile Gly Val Asn Asp Ser Asn Leu Phe Ser Leu Glu Met Arg
                 335                 340                 345

 Glu Pro Leu Glu Ser Ser Asn Thr Lys Ser Phe His Ser Ala Val
                 350                 355                 360

 Glu Ile Lys Asn Arg Ser Gln His Glu Leu Pro Cys Phe Gln His
                 365                 370                 375

 His Gly Ile Asp Thr Pro Thr Ser Leu Gln Lys Arg Ser Ala Cys
                 380                 385                 390

 Cys Pro Pro Ser Leu Leu Arg Leu Glu Glu Thr Ala Ser Ser Ser
                 395                 400                 405

 Gln Asp Gly Asp Pro Gln Ile Trp Asp Asp Leu Pro Phe Ser Glu
                 410                 415                 420

 Ser Leu Asn Lys Phe Leu Ala Val Leu Glu Ser Glu Ile Ala Val
                 425                 430                 435

 Thr Gln Ala Asp Val Ser Ser Arg Lys His His Val Asp Asn Asp
                 440                 445                 450

 Ile Asp Lys Phe His Ala Asp His Ser Ser Leu Ser Val Thr Pro
                 455                 460                 465

 Gln Arg Thr Thr Gly Ala Leu His Thr Pro Pro Ile Ala Leu Arg
                 470                 475                 480

 Ser Ser Gln Val Ile Val Lys Ala Asn Cys Ser Lys Asp Asp Phe
                 485                 490                 495

 Leu Phe Asn Cys Lys Gly Asn Leu Ser Pro Ser Val Glu Lys Glu
                 500                 505                 510

 Ser Gln Pro Asp Asn Lys Val Glu Ala Val Ser Val Asn His Asn
                 515                 520                 525

 Gly Arg Asp Met Ser Glu Tyr Phe Leu Pro Asn Pro Tyr Leu Ser
                 530                 535                 540

 Ala Leu Ser Ser Ser Ser Lys Asp Leu Glu Thr Ile Val Thr Leu
                 545                 550                 555

 Lys Lys Thr Ile Arg Ile Ser Pro His Arg Glu Ser Asp His Ser
                 560                 565                 570

 Ser Leu Asn Asn Lys Tyr Leu Asn Gly Cys Gly Glu Ile Ser Val
                 575                 580                 585

 Ser Glu Met Asn Glu Lys Leu Thr Thr Leu Cys Tyr Arg Lys Tyr
                 590                 595                 600

 Asn Asp Val Ser Asp Leu Cys Lys Leu Glu Asn Lys Gln Tyr Cys
                 605                 610                 615

 Arg Trp Ser Lys Asn Gln Asp Asp Ser Phe Thr Ile Cys Arg Lys
                 620                 625                 630

 Leu Thr Tyr Pro Leu Glu Thr Leu Cys Asn Ser Pro Asn Arg Ser
                 635                 640                 645

 Thr Asn Thr Leu Lys Glu Met Pro Trp Gly His Ile Asn Asn Asn
                 650                 655                 660

 Val Thr Gln Ser Tyr Ser Ile Gly Tyr Glu Gly Ser Tyr Asp Ala
                 665                 670                 675

 Ser Ala Asp Leu Phe Asp Asp Ile Ala Lys Glu Met Asp Ile Ala
                 680                 685                 690

 Thr Glu Ile Thr Lys Lys Ser Gln Asp Ile Leu Leu Lys Trp Gly
                 695                 700                 705

 Thr Ser Leu Ala Glu Ser His Pro Ser Glu Ser Asp Phe Ser Leu
                 710                 715                 720

 Arg Ser Leu Ser Glu Asp Phe Ile Gln Pro Ser Gln Lys Leu Ser
                 725                 730                 735

 Leu Gln Ser Leu Ser Asp Ser Arg His Ser Arg Thr Cys Ser Pro
                 740                 745                 750

 Thr Pro His Phe Gln Ser Asp Ser Glu Tyr Asn Phe Glu Asn Ser
                 755                 760                 765

 Gln Asp Phe Val Pro Cys Ser Gln Ser Thr Pro Ile Ser Gly Phe
                 770                 775                 780

 His Gln Thr Arg Ile His Gly Ile Asn Arg Ala Phe Lys Lys Pro
                 785                 790                 795

 Val Phe Tyr Ser Asp Leu Asp Gly Asn Tyr Glu Lys Ile Arg Ile
                 800                 805                 810

 Phe Pro Glu Asn Asp Lys Gln Gln Ala Ser Pro Ser Cys Pro Lys
                 815                 820                 825

 Asn Ile Lys Thr Pro Ser Gln Lys Ile Arg Ser Pro Ile Val Ser
                 830                 835                 840

 Gly Ile Ser Gln Pro Asp Val Phe Asn His Tyr Pro Phe Ala Glu
                 845                 850                 855

 Cys His Glu Thr Asp Ser Asp Glu Trp Val Pro Pro Thr Thr Gln
                 860                 865                 870

 Lys Ile Phe Pro Ser Asp Met Leu Gly Phe Gln Gly Ile Gly Leu
                 875                 880                 885

 Gly Lys Cys Leu Ala Ala Tyr His Phe Pro Asp Gln Gln Glu Leu
                 890                 895                 900

 Pro Arg Lys Lys Leu Lys His Ile Arg Gln Gly Thr Asn Lys Gly
                 905                 910                 915

 Leu Ile Lys Lys Lys Leu Lys Asn Met Leu Ala Ala Val Val Thr
                 920                 925                 930

 Lys Lys Lys Thr His Lys Tyr Asn Cys Lys Ser Ser Gly Trp Ile
                 935                 940                 945

 Ser Lys Cys Pro Asp Ile Gln Val Leu Ala Ala Pro Gln Leu His
                 950                 955                 960

 Pro Ile Leu Gly Pro Asp Ser Cys Ser Glu Val Lys Cys Cys Leu
                 965                 970                 975

 Pro Phe Ser Glu Lys Gly Pro Pro Ser Val Cys Glu Thr Arg Ser
                 980                 985                 990

 Ala Trp Ser Pro Glu Leu Phe Ser
                 995

<210> 4630
<211> 661
<212> DNA
<213> Homo sapien

<400> 4630
 ggcgcaacgg gcggcggaag taggagcctg ggaaggaaga gggaacgggt 50

 cctggcggtg ctttgcaaag ggcccgtgtt tctgttgcgg gaagctcccg 100

 ggggtcgcac gtgcgtccga gcccaagccc ctcccctcca ctccccttcc 150

 tgcgtgcccc ggagccgcca agcggctacg ttcttctcgg cccgccgaga 200

 tggcgctcga ccccgcagac cagcatctca gacatgtcga aaaagatgtt 250

 ttgatcccta aaataatgag agaaaaggcc aaagagaggt gttctgaaca 300

 agttcaagat tttaccaaat gttgcaagaa ctctggagtt cttatggtag 350

 taaaatgccg gaaagaaaat tctgcattga aagaatgtct aactgcttac 400

 tataatgatc cagcctttta tgaagaatgc aaaatggaat acctgaagga 450

 aagggaagaa ttcagaaaaa ctggaattcc tacaaagaaa aggctacaga 500

 agcttccaac aagcatgtag gcagatactc aaatgacatt caggaactct 550

 aatattcatg gaagtcattt tatagtcctt aaataatgga ctcaagcata 600

 tatgtttgct ttaccttaat tatggaaata ttaactttat ctgaaataaa 650

 tattttattt c 661

<210> 4631
<211> 172
<212> PRT
<213> Homo sapien

<400> 4631
 Ala Gln Arg Ala Ala Glu Val Gly Ala Trp Glu Gly Arg Gly Asn
   1               5                  10                  15

 Gly Ser Trp Arg Cys Phe Ala Lys Gly Pro Cys Phe Cys Cys Gly
                  20                  25                  30

 Lys Leu Pro Gly Val Ala Arg Ala Ser Glu Pro Lys Pro Leu Pro
                  35                  40                  45

 Ser Thr Pro Leu Pro Ala Cys Pro Gly Ala Ala Lys Arg Leu Arg
                  50                  55                  60

 Ser Ser Arg Pro Ala Glu Met Ala Leu Asp Pro Ala Asp Gln His
                  65                  70                  75

 Leu Arg His Val Glu Lys Asp Val Leu Ile Pro Lys Ile Met Arg
                  80                  85                  90

 Glu Lys Ala Lys Glu Arg Cys Ser Glu Gln Val Gln Asp Phe Thr
                  95                 100                 105

 Lys Cys Cys Lys Asn Ser Gly Val Leu Met Val Val Lys Cys Arg
                 110                 115                 120

 Lys Glu Asn Ser Ala Leu Lys Glu Cys Leu Thr Ala Tyr Tyr Asn
                 125                 130                 135

 Asp Pro Ala Phe Tyr Glu Glu Cys Lys Met Glu Tyr Leu Lys Glu
                 140                 145                 150

 Arg Glu Glu Phe Arg Lys Thr Gly Ile Pro Thr Lys Lys Arg Leu
                 155                 160                 165

 Gln Lys Leu Pro Thr Ser Met
                 170

<210> 4632
<211> 2091
<212> DNA
<213> Homo sapien

<400> 4632
 attgtttaat caaaggaaga gtcaaaataa gctacaccca gattactgag 50

 aaaggtgaaa tgaaaacaag ctcaaaacca aattccagga agatgctgtc 100

 tttgtattga cttaccattt catgttttca cacatgtcaa agtcttgaag 150

 cttcggtcat tagtcttccg cttcctaaag caagaaacta aatgctgact 200

 tgtgtcgttt gccccagatg ccaccggaaa tgtcatcttc tccccagacg 250

 ctggcttgca agcacagcag cacccagagg ctaacctatt tcccctatag 300

 cccaagctct gagatctccc gtctggtcac aatgatctac aggagaggaa 350

 gaaagctatc tagggacgag atctagaatc aactgagaga gatgcttaaa 400

 aatcaccagt tactttaatg accatccgca gagccatcct gtgcaaagga 450

 aggagctagg ctgtgcgccc tgggcgtcat gatccttctg cgggcctccg 500

 aagtgcggca gctgcttcac aataagttcg tggtcatcct gggggactct 550

 gtgcataggg cagtatacaa ggacctggtg cttctgctgc agaaggaccg 600

 cctgctcact cccgggcagc ttagagcaag gggggagctg aacttcgaac 650

 aagatgagct ggtggacgga ggccagcggg gccacatgca caacggcctt 700

 aactaccgtg aggtccgcga gttccgctcc gaccaccatc tggtacgttt 750

 ttacttcctc acccgcgtgt actccgatta cctccagacc atcttgaaag 800

 agctgcagtc gggcgagcac gcccccgacc tggtcatcat gaattcctgc 850

 ctctgggaca tctccaggta tggtccgaac tcctggagaa gctacctgga 900

 gaacctggag aacctgttcc agtgcctggg ccaggtgctg cccgagtctt 950

 gcctcctggt gtggaacacg gccatgcctg tgggcgagga agtcaccggg 1000

 ggttttcttc cgcccaagct ccggcggcag aaggccacct tcctgaaaaa 1050

 cgaagtggtc aaagccaact tccacagcgc caccgaggca cgtaaacata 1100

 acttcgatgt actggacttg catttccact tccgccacgc gagggagaac 1150

 ctgcactggg acggggtgca ctggaatgga cgtgtgcacc gctgcctctc 1200

 ccagctgctg ctggcccacg tggccgacgc ctggggtgtg gagctgcccc 1250

 accgccaccc cgtgggcgag tggatcaaga agaaaaaacc tggcccgaga 1300

 gtcgaagggc cgccccaggc caacagaaat cacccggcct tacctctgtc 1350

 cccaccctta ccttccccca cataccgccc cctgcttggg ttcccacccc 1400

 agcgcttgcc gctgctcccg ctcctgtccc cacagcctcc tcctcccatt 1450

 ctccatcacc agggaatgcc ccggttccca cagggtcccc cagatgcctg 1500

 tttttcctca gaccatactt tccagtcgga tcaattctat tgccattcag 1550

 atgtcccctc atcagcccat gcaggtttct tcgtcgaaga caattttatg 1600

 gttggtcctc agctgcctat gcccttcttc cccacacccc gttatcagcg 1650

 gcctgcccca gtggtacata ggggttttgg caggtatcgt ccccgtggcc 1700

 cctatacgcc ctggggacag cggcctcgac cttcaaagag aagggcccca 1750

 gccaatcctg agccaaggcc tcaatagacg gacctaggcc ttatttcctc 1800

 tttatgaaca tggattggac agatctgaca cttcctttcc attgcttggc 1850

 ctgaacagac tgaccttgtt aacttaagcc tggagtccat gcctcgtctt 1900

 ccttttgttc attgctgtta ccaagaaagc caaggaagag cagcctgact 1950

 cattcttctt ggctgcagcc tcttccccac ttcctgggag tgacccagcg 2000

 ttattcctgc ctcctcactc ctattctctt tgcctttgtg taaaaataaa 2050

 atggaaataa acaagttgca cagaaaaaaa aaaaaaaaaa a 2091

<210> 4633
<211> 432
<212> PRT
<213> Homo sapien

<400> 4633
 Met Ile Leu Leu Arg Ala Ser Glu Val Arg Gln Leu Leu His Asn
   1               5                  10                  15

 Lys Phe Val Val Ile Leu Gly Asp Ser Val His Arg Ala Val Tyr
                  20                  25                  30

 Lys Asp Leu Val Leu Leu Leu Gln Lys Asp Arg Leu Leu Thr Pro
                  35                  40                  45

 Gly Gln Leu Arg Ala Arg Gly Glu Leu Asn Phe Glu Gln Asp Glu
                  50                  55                  60

 Leu Val Asp Gly Gly Gln Arg Gly His Met His Asn Gly Leu Asn
                  65                  70                  75

 Tyr Arg Glu Val Arg Glu Phe Arg Ser Asp His His Leu Val Arg
                  80                  85                  90

 Phe Tyr Phe Leu Thr Arg Val Tyr Ser Asp Tyr Leu Gln Thr Ile
                  95                 100                 105

 Leu Lys Glu Leu Gln Ser Gly Glu His Ala Pro Asp Leu Val Ile
                 110                 115                 120

 Met Asn Ser Cys Leu Trp Asp Ile Ser Arg Tyr Gly Pro Asn Ser
                 125                 130                 135

 Trp Arg Ser Tyr Leu Glu Asn Leu Glu Asn Leu Phe Gln Cys Leu
                 140                 145                 150

 Gly Gln Val Leu Pro Glu Ser Cys Leu Leu Val Trp Asn Thr Ala
                 155                 160                 165

 Met Pro Val Gly Glu Glu Val Thr Gly Gly Phe Leu Pro Pro Lys
                 170                 175                 180

 Leu Arg Arg Gln Lys Ala Thr Phe Leu Lys Asn Glu Val Val Lys
                 185                 190                 195

 Ala Asn Phe His Ser Ala Thr Glu Ala Arg Lys His Asn Phe Asp
                 200                 205                 210

 Val Leu Asp Leu His Phe His Phe Arg His Ala Arg Glu Asn Leu
                 215                 220                 225

 His Trp Asp Gly Val His Trp Asn Gly Arg Val His Arg Cys Leu
                 230                 235                 240

 Ser Gln Leu Leu Leu Ala His Val Ala Asp Ala Trp Gly Val Glu
                 245                 250                 255

 Leu Pro His Arg His Pro Val Gly Glu Trp Ile Lys Lys Lys Lys
                 260                 265                 270

 Pro Gly Pro Arg Val Glu Gly Pro Pro Gln Ala Asn Arg Asn His
                 275                 280                 285

 Pro Ala Leu Pro Leu Ser Pro Pro Leu Pro Ser Pro Thr Tyr Arg
                 290                 295                 300

 Pro Leu Leu Gly Phe Pro Pro Gln Arg Leu Pro Leu Leu Pro Leu
                 305                 310                 315

 Leu Ser Pro Gln Pro Pro Pro Pro Ile Leu His His Gln Gly Met
                 320                 325                 330

 Pro Arg Phe Pro Gln Gly Pro Pro Asp Ala Cys Phe Ser Ser Asp
                 335                 340                 345

 His Thr Phe Gln Ser Asp Gln Phe Tyr Cys His Ser Asp Val Pro
                 350                 355                 360

 Ser Ser Ala His Ala Gly Phe Phe Val Glu Asp Asn Phe Met Val
                 365                 370                 375

 Gly Pro Gln Leu Pro Met Pro Phe Phe Pro Thr Pro Arg Tyr Gln
                 380                 385                 390

 Arg Pro Ala Pro Val Val His Arg Gly Phe Gly Arg Tyr Arg Pro
                 395                 400                 405

 Arg Gly Pro Tyr Thr Pro Trp Gly Gln Arg Pro Arg Pro Ser Lys
                 410                 415                 420

 Arg Arg Ala Pro Ala Asn Pro Glu Pro Arg Pro Gln
                 425                 430

<210> 4634
<211> 3276
<212> DNA
<213> Homo sapien

<400> 4634
 tgaacatcct cagatttggt gttcgagggc atcctggaat caattcccca 50

 tgataccgag ggatgactgg atattaatcg atttccctca agcctgccct 100

 tgctgtgaac tagtgctaca agcacgggaa atccatctgc tctctggctt 150

 aaaatatgta tctcatctaa aattgttcgt taaagtgtga ataaattgct 200

 aagtggttgt tgcttagcaa taatttttgc ctgaccatca gcagagcttt 250

 tatttacctt tgtaattaaa atccaacata gcatgggctc tgggcaaaat 300

 atttcactga ctattaagca tgtagaacag gaaaatgaaa tacactattt 350

 gtgcccttga cctagaacca gaaccactaa ttatgagaac tttgttttat 400

 gtaccaaatt cacattgacc attttctgag ctctagactg atcgtagtaa 450

 gttttgtgac ttaacaatga aagaaagtag aaagatgctt tgggttttca 500

 aaatgttgtt ttttaaaatt gttctttggg tgaatttact cagtgctgct 550

 ttgatttgta tacagaaaca aatgttggga attgctcctc agaaatgtgt 600

 tcctaagttg tgttttcaac tttacatcat gaggtgaagc attagggaaa 650

 gagattcttt cgatttgttt aataatctaa ttatacagac caaagtgctt 700

 tacgtttctg ctctatgtta atgttttaga atggtgattt tgctgattaa 750

 tttagacctg gaattgaaat aatgtgctca gaataataac atggttatag 800

 ttcttgtatg ataaagtatt caatttcaga atagtgttgg aatcctgagt 850

 ttgaataatg tgttgtattt agaaacatag ccctatctgt tttaaacaaa 900

 taatttgttg gccgattgtc catggttgag catgacaaaa atacctcgtc 950

 gaaaggcaag cttaggtaac tgctggcaaa acactgggtg cactattttt 1000

 ctggataaaa tttatagtta ttttctatat tacccttcaa aagggatctc 1050

 ttcaggttaa aaatcacgct tatgctgaag tctttatctg gtgttaacta 1100

 aaaatctcat atgggttcat aaccgaggtc actaataatt catttttatc 1150

 acttgtaaaa atttgctcaa aattccaaaa aaatattgat ttgtttttta 1200

 gtgattttgc aggctgaccc ccaacctaag ttttgataac atctggtaag 1250

 tcagtatagt tctgtgactt catgttttaa ctaagaagga aaattcatag 1300

 atattcctat tagattttat aaaccttcaa aagtctgaaa cttaattttg 1350

 agtctaaatt ttctgacact ggcccctttt aatatttaag tttttgttca 1400

 ctttcttaag taaaaaaaac atttaattac tagttagccc ttaactggga 1450

 aactcaggta atgaactgct gacttttcta aagttcttta actgatcaat 1500

 tctgtataga gggatattta tctaaccact ttccgtattt tacaagtgct 1550

 ctttctaaaa aggaataact attatagctc tatttcccca atctctatag 1600

 gactcatgag agattgcttg tgtaaatata aaagcaccat atgtgttctt 1650

 aactcctatg gctgcttgaa gctcatgatg aaaaagtctt tttgtcagtt 1700

 ttaattgtta agtacagaac aaacaattgt ttggtgatgg cctggttgaa 1750

 agagagcata taaatatatc ccagtggaac tcaccaaaga agaccacacc 1800

 tcagaaatta ttgcattttc tcattatgtg ttgggtttga tttgcttttg 1850

 tttttaatgc agctctttta atataaagat tcttgataca gtgaaatctc 1900

 ttatttcaag tgtaagttat tcttcaccca ccccttcccc tgccattgta 1950

 tttcccatct gtttcaagga gtttcaacaa tttacattgc atcgtatgca 2000

 gtaggtactg ctttttcaga aagacctgga aaacatacct gctatgaata 2050

 ttttgttcag atgtagccat ttacctggct ctcaagttgt ctttgtggag 2100

 agggtcttag acaaaaatct tccttgtatt tacttgggtt aagtgaagtc 2150

 caaattctta cagtatgcta tttcaggatt tctgatatta aaaaagaaaa 2200

 aacaaaatct ttatatctct tattaacact tcccccaaga agggttgtgc 2250

 tgttatttat tttctattat aagaaaagtt cattctttaa gtagtttctt 2300

 ttacctctaa tctaatttca taccaaatac ctgatcaata gaaatgatat 2350

 atttaagcag caaagattcc taatccatca ttatgaaaag tgtcagcata 2400

 cttagtagtg aacagataaa gtcaatttga atataattcc actttgtttt 2450

 tagagactaa attaagattc aattaacatt atcctatgaa ttctgaatgt 2500

 gataatgtga ttcaaacagt caaattttat taagctctta gtaactcagg 2550

 atagcattcc atactaacct caagttagca aaacaaatta gttaaacagc 2600

 ttggttctta gcagactgct taaaagatca agaaaatttt ctcatctttt 2650

 ctttctactt agaaacattg caagaaacct tggacagtct tcaccagacc 2700

 tgccatgatt ttataagatt taggcctcag tgacatgctc ctgaaagttt 2750

 cctgccagcc atccaaacta agcatccact cattccatct tcccaaagtc 2800

 actcaccgat aaaggtagca tccttaagtt catttttgaa aggtggagga 2850

 ggatctcccc ctgcccaaag gaattttttt atcagaatac cttgaaaggg 2900

 gggtatataa atttggaaaa cttaatttct tggctgtgtt tgataacagt 2950

 tcctatgcat ggtttttaat gtgaggtaaa tttgtttctt tcttcagaat 3000

 acctctctcc accccccacc ttattcttcc tctttaatga atatttttat 3050

 tggagctcaa actccatgac ttacgtgctc actaagtttt cttttttccc 3100

 cttgtttact ctgtctgtat gtatgtcaaa agctggcaaa acctctaaaa 3150

 ctgtcaagaa aatgcttgaa agttgatttg tcatagtgca aattcatgat 3200

 aaaatgtctt aatgttattt ggatatgtag tacatagaaa cagaaaaata 3250

 aagtcatttt tataacttaa aataaa 3276

<210> 4635
<211> 62
<212> PRT
<213> Homo sapien

<400> 4635
 Glu His Pro Gln Ile Trp Cys Ser Arg Ala Ser Trp Asn Gln Phe
   1               5                  10                  15

 Pro Met Ile Pro Arg Asp Asp Trp Ile Leu Ile Asp Phe Pro Gln
                  20                  25                  30

 Ala Cys Pro Cys Cys Glu Leu Val Leu Gln Ala Arg Glu Ile His
                  35                  40                  45

 Leu Leu Ser Gly Leu Lys Tyr Val Ser His Leu Lys Leu Phe Val
                  50                  55                  60

 Lys Val


<210> 4636
<211> 4274
<212> DNA
<213> Homo sapien

<400> 4636
 ttccacgttt cttctagata gatgttaaag tagcttaatc acaaaattat 50

 aattccaaga gctgaaaggg acttaaatca actggatttt caggtgaaga 100

 taacactttt attcacgtaa gagatatgag tccaccggtg actatgttct 150

 gaggctgcag ttggaatcag acagacatga cctcctacgc agcaccagta 200

 tgcatgagcg ggtgaaccga acagaaagac agtttcgatc acttccagct 250

 aaccaacaga aactacttcc tcagtttctt cttcacttgg acaagatccg 300

 gaaatgcatt gatcataatc aagaaatact actgaccatt gtgaatgatt 350

 gcatacatat gtttgaaaat aaagaatatg gagaagatgg gaatggaaag 400

 attatgccag catctacatt tgacatggat aagttaaaat ccacgctgaa 450

 acagttgtga gagactggag tgaaactggg aaagcagaaa gggatgcctg 500

 ttaccagcca atcattaaag aaattttaaa aaattttcca aaagagagat 550

 gggatccttc taaagtaaat attctggtac ctggtgctgg actaggaaga 600

 ctggcctggg aaatagctat gctaggttat gcttgtcaag gaaatgaatg 650

 gagttttttt atgctctttt cttccaactt tgtactcaac agatgttctg 700

 aaattaataa atataaactt tatccttgga tccatcagtt tagcaataac 750

 cggagatcag ctgatcagat tcgacccatc tttttccctg atgttgaccc 800

 ccacagtctt cctcctggtt ctaacttttc tatgacagca ggagattttc 850

 aagagattta ttcagaatgc aatacctggg actgtattgc tacctgtttc 900

 ttcatagaca cagctcacaa tgtaattgat tatattgata caatatggaa 950

 aatactcaag ccaggtggaa tttggataaa tctaggtcct ctgctgtacc 1000

 actttgaaaa tctggcaaat gaactttcca tagaattgag ctatgaggat 1050

 ataaaaaacg ttgttctgca gtatggattc aaggtagagg tggaaaaaga 1100

 atctgtattg tcaacatata ctgtgaatga tctctctatg atgaaatact 1150

 actatgaatg tgtcttgttt gtggtccgta agccacaata atggtctcaa 1200

 gtgataccac ctggaaaaaa gtttagtaag aacaaatgct gaaatcaacg 1250

 actcaaaatc aactatcagt gatgacagga cacaacctca aatcagtggt 1300

 gccttcttat tcctaacgaa atttagaaat agtgtctatt ttcttaatat 1350

 gtctattgct ttttcagaaa tatactatgc catgcagatt tgtactacac 1400

 aagtaaaaat ggaggaaatg tcttgaagta tactttttcc ttgaagccca 1450

 gaattgtgtt tcagtaggaa aaaaacctaa tctccagtgt cttcatgatg 1500

 ctgtccattg caagtctgcc gaattaatga ctaatagtat tgaagtacat 1550

 aataatcttc ctttttttgt tgttttgtat gcattgcaca tgtaactttt 1600

 agaagagtct aaggatcctc agtcatattc aacatctgga gttgggactt 1650

 tgttcacttt caatctaaga aaactatgtg taaaatatgt cttttttttt 1700

 ttttccttct caagaaaacg ggattcccgc ctcgtgttcc tcccaggccg 1750

 gagttgcagg ggcaacgact catagcctca cttgtaacct caaacctccg 1800

 tggactcaag cgatctatcc gtgccattag ccttagccct ccgtgagtat 1850

 agctaggacg tggtaggcat gtgtaccacc gcgcctgggc ctgtgtctat 1900

 tttatcattc agattaattt aattttgtat tttctggctc agatgaactt 1950

 aaagaagcat caaacatttc ttttttatga aatgttaaat ttaatagcat 2000

 cacaggccgg taaaatatat tcaagtaaca gaaatatcaa agtcttttgg 2050

 ccacaataaa ctgaacactt tatgaaagca tactcatcat ggatcacttt 2100

 gaaatatacg agatctcaac attcaaagtg agaaataaaa agcctttatt 2150

 aaaagtagtg ctaggaaaca gagaaaataa gaataaaatt tacccatttg 2200

 aaatatgtga ttttcagact ctaaatgaat acagagtttg acagtgtgat 2250

 gtttacaata atgtcttttc tttagaatat ctggattatg aaagcaagca 2300

 cttttttcat taaaaaaatt atatactagg aaaaactgtc ataatagtat 2350

 taatgtgggg aattttgatt atgaaattca gggatatatt actgcccgtg 2400

 gtctgtgtct tcaatattgt aagcagcagc catcatgtaa tttcagatta 2450

 ataccaattt tgttccctga tagatggagc ttaaacagta tatgctgctt 2500

 taaatttcta cctctagcag atctttattg gagggagttt tcctttgtat 2550

 tttttaatgt atgatattct gtttccagta gcttggaaag tagagatgac 2600

 taatgtttta gccttttctt ggagaaaagg aagaactctt cttgaatatt 2650

 ttcacagatg attgtgattg ctttaaatga cctctgtggc aatttaaatt 2700

 agatggattt aatctcagta atgtgctggt cgcataaatg tcatgtttta 2750

 ataggaaaag ttacttgtaa atctttagac ctttgttgtc acttaggctg 2800

 gggagtcact accctatttg gcatcttact agttgggggg accttttccg 2850

 tgtacagtga tgggactttt gtgaccttta ctctcactat gcaatagagg 2900

 gtttcatgta gttaatctga catgtcaaaa ttgggaagac tgtaaccttt 2950

 tttttttttt ttaagatttc tcttttttgt gtccctcaat acttagcaga 3000

 tgttcatttg gtggaaattc ttattactta catgaatgag tttgaattta 3050

 gtggcaagga agaaaaaaaa aactcaaatt attgttttaa aagaagaaaa 3100

 cttgcaaagt acataagtat tttttaaaaa tcaatcgaac agaaaggaat 3150

 gcatgctgtt tttcaatggc ttagacatgc tttttattca ctgactagta 3200

 ttcacttttt tacaacttgt atcaaaacaa atgatctttg tttttgtcac 3250

 aggcaaaaac aggttgacac tggtgggttg gctttattaa ttaatttttt 3300

 ttctattagg ttttctttaa taatgttaaa tttctaaatt atagcatatg 3350

 ttttagttaa ttctgaaatc agttacttca tttgttaatt tatccctcat 3400

 atcatgaata ttgtttttta aatgttctat acaaatttgc atcacttctt 3450

 ttcttacagc ttttgcagtt aatatattct aaacttgaaa atgtggtatc 3500

 aatcaataat agaagtatca ctggaggatt tatttagctt tgtatttctt 3550

 aattttagtc ctagctacta aagtatgtaa gccttaaagt ttaaaatgtt 3600

 tttcttaaat tagctttata cacaaacatt ttcatttact ttatgaaatg 3650

 ggaggagata gtccactgtg cttatgtttt tttgtttaat ttctatattc 3700

 tgaagcagtg cagatatagg gtatgctaat caagtgagca aggtggaaca 3750

 tgtacaatat aaggagaagc tgtaaaaatc acagtataaa attatgaagt 3800

 ttggtaactg taaaatgtac tgtatttata tgtaactctc attctaaaag 3850

 ttgccacaaa agctgaattg gaagcttcat gtctgcatga aatttcctat 3900

 atttttaatg tgtatgatga aattaatttt tcttgaatat taaagtctgc 3950

 caatgtttgg gagtgcagcc tatcttctag aaccctgaag cttggcattc 4000

 attgttcata aactcagctc gaaggcagtg ccttccaaat gtggttaaat 4050

 tgccatggga aagaccaggg ttagttgcag ggcatcattt tccaagcaga 4100

 accatttcaa atgctaaaac tggcccctga ggttacattg agcctccctt 4150

 cctgagtgag atgtttggaa atgaggtggc tgtggaaacc actgttacag 4200

 acaagcttag ttccaaagcc acctcatgtc gtaagagatg agtcaggaag 4250

 ggcggcggct ctagactcga gact 4274

<210> 4637
<211> 190
<212> PRT
<213> Homo sapien

<400> 4637
 Met Leu Gly Tyr Ala Cys Gln Gly Asn Glu Trp Ser Phe Phe Met
   1               5                  10                  15

 Leu Phe Ser Ser Asn Phe Val Leu Asn Arg Cys Ser Glu Ile Asn
                  20                  25                  30

 Lys Tyr Lys Leu Tyr Pro Trp Ile His Gln Phe Ser Asn Asn Arg
                  35                  40                  45

 Arg Ser Ala Asp Gln Ile Arg Pro Ile Phe Phe Pro Asp Val Asp
                  50                  55                  60

 Pro His Ser Leu Pro Pro Gly Ser Asn Phe Ser Met Thr Ala Gly
                  65                  70                  75

 Asp Phe Gln Glu Ile Tyr Ser Glu Cys Asn Thr Trp Asp Cys Ile
                  80                  85                  90

 Ala Thr Cys Phe Phe Ile Asp Thr Ala His Asn Val Ile Asp Tyr
                  95                 100                 105

 Ile Asp Thr Ile Trp Lys Ile Leu Lys Pro Gly Gly Ile Trp Ile
                 110                 115                 120

 Asn Leu Gly Pro Leu Leu Tyr His Phe Glu Asn Leu Ala Asn Glu
                 125                 130                 135

 Leu Ser Ile Glu Leu Ser Tyr Glu Asp Ile Lys Asn Val Val Leu
                 140                 145                 150

 Gln Tyr Gly Phe Lys Val Glu Val Glu Lys Glu Ser Val Leu Ser
                 155                 160                 165

 Thr Tyr Thr Val Asn Asp Leu Ser Met Met Lys Tyr Tyr Tyr Glu
                 170                 175                 180

 Cys Val Leu Phe Val Val Arg Lys Pro Gln
                 185                 190

<210> 4638
<211> 510
<212> DNA
<213> Homo sapien

<400> 4638
 atgggttggt ctcaggattt gttccgcgcc ttgtggagat cgctgtcaag 50

 ggaagtgaag gagcacgtgg gcacggacca attcgggaac aaatactact 100

 acatcccgca gtacaagaac tggagaggac aaactattcg agagaaaaga 150

 attgtagaag cagcaaataa aaaagaagta gactatgaag caggggatat 200

 tccaacagaa tgggaagctt ggattagaag aacaagaaag actccaccta 250

 ctatggagga aatactaaag aatgaaaaac acagagaaga aatcaaaata 300

 aaaagccaag atttttatga aaaagaaaaa ctccttagta aagagaccag 350

 tgaggaactc ctgcctccac cagttcaaac tcaaattaaa ggccatgcct 400

 ctgctccata ctttggaaag gaagaaccct cagtggctcc cagcagcact 450

 ggtaaaacct ttcagccagg atcctggatg ccacgagatg gcaagagcca 500

 caatcaatga 510

<210> 4639
<211> 169
<212> PRT
<213> Homo sapien

<400> 4639
 Met Gly Trp Ser Gln Asp Leu Phe Arg Ala Leu Trp Arg Ser Leu
   1               5                  10                  15

 Ser Arg Glu Val Lys Glu His Val Gly Thr Asp Gln Phe Gly Asn
                  20                  25                  30

 Lys Tyr Tyr Tyr Ile Pro Gln Tyr Lys Asn Trp Arg Gly Gln Thr
                  35                  40                  45

 Ile Arg Glu Lys Arg Ile Val Glu Ala Ala Asn Lys Lys Glu Val
                  50                  55                  60

 Asp Tyr Glu Ala Gly Asp Ile Pro Thr Glu Trp Glu Ala Trp Ile
                  65                  70                  75

 Arg Arg Thr Arg Lys Thr Pro Pro Thr Met Glu Glu Ile Leu Lys
                  80                  85                  90

 Asn Glu Lys His Arg Glu Glu Ile Lys Ile Lys Ser Gln Asp Phe
                  95                 100                 105

 Tyr Glu Lys Glu Lys Leu Leu Ser Lys Glu Thr Ser Glu Glu Leu
                 110                 115                 120

 Leu Pro Pro Pro Val Gln Thr Gln Ile Lys Gly His Ala Ser Ala
                 125                 130                 135

 Pro Tyr Phe Gly Lys Glu Glu Pro Ser Val Ala Pro Ser Ser Thr
                 140                 145                 150

 Gly Lys Thr Phe Gln Pro Gly Ser Trp Met Pro Arg Asp Gly Lys
                 155                 160                 165

 Ser His Asn Gln


<210> 4640
<211> 2917
<212> DNA
<213> Homo sapien

<400> 4640
 ctagaatgct aattgcactt aggcctcatg gttctagtaa acggcagctg 50

 tgggcccttt tgcctcttcc cctgttcttg gcctcacatc tccagctgag 100

 ctgccggtct tggcttcctg gtcgcctctg tcccagagat ggtcccaggg 150

 agccatccta gggcaggtag cactgaggct cctgtggaaa caggagccac 200

 ctgctcagga gacccctttc ctgaggaagt ccttacctct ccccttgaga 250

 tgtaaaaatg gtccagcaga gacaagctcc cgtggaaaac agacaggagc 300

 atgggggcag ctgtcatggc tgtggcgggc acttttcctc agagtttctg 350

 ccttgcgctg gtccaggagc cattttgcac caaggacttg gtaggcagag 400

 gcagccccac tgtaaagaag ggtcagatta aaacaaaaaa ctgccaaaag 450

 catcccctct gccccccatg tggcactggc atcattctct gcttccctgg 500

 gaggaatttt ttcaccatgt tattgaaggg gatggttcat taaggactcc 550

 acccctcaga gctcactcag accccaagga cagaggtgac tggggcttgg 600

 tgacttgttc actccttttt tcccaggtat actgaagggg tgacagagag 650

 aggtcttcat ggcagaccag gccttcacag ctaatgggga gaggaactca 700

 tgttacctct gcaggcctgg ggtcctgagg gggtcttttg gcttcagcct 750

 gttcccccag aggcttgatc atcccacatt gtcccttcag ctcagctgct 800

 cttctccccc acccaccctg ggatgtgggt gctctgggct gaaccaaggc 850

 tatgacttct ggagagaggc tcaggggttg gtctgagagg cctgccatcc 900

 acccctcagg gagctaggtt ttctcagagg ctcagctgga cagcactttt 950

 tagaaaagtt tgtagcatta agctggttta aaatatgaag ttggttttgt 1000

 tggatggctc ctgagctgac tgactgatgt ctgaagtttg agacgaggga 1050

 ttatttcagg gtggggccca atgtgatcta atgcccagct ggggacaatt 1100

 gtgcctcatc atttgctcaa attcctgggc ccccaagtta gccccctccc 1150

 aggagtggtc agcgggtcac agctgccccc actctataag cagggctaat 1200

 tgtgtaccct ttgcagaaat gcttttggtc tcctacccaa atactcacaa 1250

 gggtcttatc agacgcccgt cttaaagtcc agcatgctca gggaccctgt 1300

 gtaggatctc gtttgtggtg agtgggctgc tctgaggtct ccactgggct 1350

 gccatttagc catgtgccat ctctgaagtc agaggtgttt gactcccatt 1400

 ccttgggctc tggagctttc cccaagaatt acatcagaga aaaggaagaa 1450

 ggggcctgca ggacccattg ggaatgagtt taatactgaa gtctggaatg 1500

 taagctcatg ccctagaggc ctctccatat ggctggtcag gggagctgcc 1550

 ttcaggcttg tgccccgtgt gctcagcagc tgcctctgtc cccctctact 1600

 gtccctttca caccttgcct ggccaagggg ctagacctcc caggctaagc 1650

 ctcagattca gtgcaggaca caagctcatg cccccgtctt gccagtgaca 1700

 cttgaagcct cccgacttcc acagagtgct tcaggacaca ttttgagtgg 1750

 tattttcttt tctttttttc ttcttttttt tttttttgag atggagtctc 1800

 gctctgttgc ccaggctgga gtgcagtggc ctgatctcgg ctcactgcaa 1850

 cctctgcctc ccaggttcaa gcgattcttc tgcctcagcc tccagagtag 1900

 ctgggactat agacatgcac caccacgccc ggctaatttt gtatttttgg 1950

 tcgagacggg gttttgccat gttagtcagg ctggtcttga actcctgacc 2000

 tcaagtgatc caccacctcg gcctcccaaa gtgttgagat gacaggcacg 2050

 agccaccagg cccagcctga gtggtatttt ctttagggac caggtagact 2100

 ttaaaacgag ggtaagagaa aagccagtgt ctttctgagg taaataattt 2150

 ctgccaggaa acttcccagc cccaccagca gcccccctaa aaaaatcact 2200

 cgtgtcccca gggacttcta aagcttgggg ctccaggaaa tcatccagta 2250

 gagttggaga ttcagagatt tcttgaagcc agggacatgc tcctaactcc 2300

 tttcccatta aaggtgttag aatagaccag agggtgtccc ttttccacag 2350

 taatgggatc ggctggtgtg ccttcaggga ggaagaggga ggtggtcaag 2400

 cttgaaaaac tggctttagg atggttctga ctttgttctc cctccccaag 2450

 tgttctcaac ctccattctg cagtgttcag agttttaggg aaagggtttg 2500

 ggtgccccag catccaggtg ttgtgtggct tagcgcatgt gaagtgaaaa 2550

 ccttctgggg ttgtttggaa gcagctttct ggttcttgtg attgtatcct 2600

 gaggtcccag aaccctattc tcccacgagg atcctcagtg accatggtgg 2650

 ccacacgcct ggccagcctg ctggctcctg ggtgagctga agaaccttgc 2700

 ctgtggcact tttcgagggt gagctggaac cgagagaaca tggtccccgt 2750

 gctgggactc atgcgggtca tttcctgccg gcctggtttc gcctggtcgt 2800

 gtctttatga gcaccatgta agcctccttg tattgagata attgggcatt 2850

 aaacattaaa ctgcagctct gggaaaaaaa aaaaaaaaaa aaaaaaaaaa 2900

 aaaaaaaaaa aaaaaac 2917

<210> 4641
<211> 83
<212> PRT
<213> Homo sapien

<400> 4641
 Met Glu Ser Arg Ser Val Ala Gln Ala Gly Val Gln Trp Pro Asp
   1               5                  10                  15

 Leu Gly Ser Leu Gln Pro Leu Pro Pro Arg Phe Lys Arg Phe Phe
                  20                  25                  30

 Cys Leu Ser Leu Gln Ser Ser Trp Asp Tyr Arg His Ala Pro Pro
                  35                  40                  45

 Arg Pro Ala Asn Phe Val Phe Leu Val Glu Thr Gly Phe Cys His
                  50                  55                  60

 Val Ser Gln Ala Gly Leu Glu Leu Leu Thr Ser Ser Asp Pro Pro
                  65                  70                  75

 Pro Arg Pro Pro Lys Val Leu Arg
                  80

<210> 4642
<211> 602
<212> DNA
<213> Homo sapien

<400> 4642
 gtgagactcc ctctcaaaaa caaaacaaaa caaaaaaatt agacaaatgc 50

 tacattaatg tttgggtggt cagattctac tttgaatctg aagtttgcag 100

 atatgcctat agatttttgg agtttaccac tttcttattc tgtatcatta 150

 atgtaatatt ttaaattact atatatgtta ccatttttct ggatttagta 200

 agaaatttgc agttttggtt tgatgtaaca agggttttaa tgtaatttat 250

 gttagatttt gcattttttt cattactgtt atattttaac ctgactgact 300

 gatctaattg tattagtatt gtgaataatc atgtgaaatg ttttgagaca 350

 gagtactata tttgtgaata taattttatg gtttttttca cttagaacct 400

 ttctgtgtgg aaaactaaga aaattgcttt ctgctgtata atctggcatt 450

 cattgtagat taaagcttat ttttctgtga ataaaacgta ttcaataaaa 500

 tactattctt taaaattaaa aaaaatctat gtcgggtgcg gagaaagagg 550

 taatgaaatg cggattcgat atcagcttat catacctcac ctcgaggggc 600

 cc 602

<210> 4643
<211> 53
<212> PRT
<213> Homo sapien

<400> 4643
 Glu Thr Pro Ser Gln Lys Gln Asn Lys Thr Lys Lys Leu Asp Lys
   1               5                  10                  15

 Cys Tyr Ile Asn Val Trp Val Val Arg Phe Tyr Phe Glu Ser Glu
                  20                  25                  30

 Val Cys Arg Tyr Ala Tyr Arg Phe Leu Glu Phe Thr Thr Phe Leu
                  35                  40                  45

 Phe Cys Ile Ile Asn Val Ile Phe
                  50

<210> 4644
<211> 1491
<212> DNA
<213> Homo sapien

<400> 4644
 tggctgatca gagcgcgtag ggcttcgccg gggccgggag ctgggcgcgg 50

 tcctgctcag cccagctcac cgcgcgccgg ccctcggcgc cctggttctg 100

 cggatcagga gttgaaacca gcaccttccc tttctctgag tcctgcctcc 150

 ttctgcggaa gggagctcaa aagaactttg ttgttttgcc ttttactctg 200

 gggtgaaagc ggcaggaggt atgtgagatg gtgaaatgat ttgcttctgc 250

 catgctgggg tcacgggtgg atcgccctaa actctcggtg gccccctcag 300

 tagttttgga agaggaccaa gtccttgtct ctccagcagt ggacctggaa 350

 gaaggatgcc ggctcaggga cttcactgag aaaataatga atgtcaaagg 400

 aaaagtaatt ctgtcaatgc tggttgtctc aactgtgatc attgtgtttt 450

 gggaatttat caacagcaca gaaggctctt tcttgtggat atatcactca 500

 aaaaacccag aagttgatga cagcagtgct cagaagggct ggtggtttct 550

 gagctggttt aacaatggga tccacaatta tcaacaaggg gaagaagaca 600

 tagacaaaga aaaaggaaga gaggagacca aaggaaggaa aatgacacaa 650

 cagagcttcg gctatgggac tggtttaatc caaacttgaa ggaatccgaa 700

 taactaaact ggactctggt tttctgactc agtccttcta gaagacctgg 750

 actgagagat catgcggtta aggagtgtgt aacaggcgga ccacctgttg 800

 ggactgcgag attctcaagg ggaaggactg ggtctcattt ctcccatctc 850

 agcgcttagc aggatgacct ggtatagagc agggaactgg gaaatgtggg 900

 tcaggggatc agacactcca gttgggtctt ttatataaat taaatggcaa 950

 aaggctccat acccttctcc ttctttccta ccctccactt tatctgcaaa 1000

 atgggaatga tgataacacc cacttcatag aatggtcatg aagatcaaat 1050

 gagagaataa aagtcaagca cttagcctct ggtgcacaat aagtattaaa 1100

 taagtatacc tattcctcct tttccttttt taaaaataat attaccaaat 1150

 gtccagctta tacacattta caagacttag ctagtgggct atgttagagc 1200

 tactaaaaga tctttgacaa gctaaaacta agatgcaatg aatgaggtgt 1250

 aacgaacaag agagttttaa gttcagaaat ggttacagaa gtataagaca 1300

 gctgtgtggg tgttttttgg tttttggttt ctggtttaca atctcgtcat 1350

 tcaacaaaga tgggagtttt atagaactaa aagcaccatg taagctacta 1400

 aaaacaacaa caaaaaaggc tcatcatttc tcagtctgaa ttgacaaaaa 1450

 tgccaatgca aataaaaatg attacttttt atttttcaac g 1491

<210> 4645
<211> 145
<212> PRT
<213> Homo sapien

<400> 4645
 Met Leu Gly Ser Arg Val Asp Arg Pro Lys Leu Ser Val Ala Pro
   1               5                  10                  15

 Ser Val Val Leu Glu Glu Asp Gln Val Leu Val Ser Pro Ala Val
                  20                  25                  30

 Asp Leu Glu Glu Gly Cys Arg Leu Arg Asp Phe Thr Glu Lys Ile
                  35                  40                  45

 Met Asn Val Lys Gly Lys Val Ile Leu Ser Met Leu Val Val Ser
                  50                  55                  60

 Thr Val Ile Ile Val Phe Trp Glu Phe Ile Asn Ser Thr Glu Gly
                  65                  70                  75

 Ser Phe Leu Trp Ile Tyr His Ser Lys Asn Pro Glu Val Asp Asp
                  80                  85                  90

 Ser Ser Ala Gln Lys Gly Trp Trp Phe Leu Ser Trp Phe Asn Asn
                  95                 100                 105

 Gly Ile His Asn Tyr Gln Gln Gly Glu Glu Asp Ile Asp Lys Glu
                 110                 115                 120

 Lys Gly Arg Glu Glu Thr Lys Gly Arg Lys Met Thr Gln Gln Ser
                 125                 130                 135

 Phe Gly Tyr Gly Thr Gly Leu Ile Gln Thr
                 140                 145

<210> 4646
<211> 2116
<212> DNA
<213> Homo sapien

<400> 4646
 cccaagagag atgggctggt gggtcactga cataaagcag tccacaagat 50

 ctattttaga aaagtatcaa tgacatttcc ttagttggtt tgattctctt 100

 gagaatacat gagtttaaaa gaactgaggt caaattgctt tatgtggaaa 150

 gcaataaaaa caagtatttt tgacttgcaa attagaggta actgtaagca 200

 atttttgcta ttgaagccta tggcccaaat tattccacct gcaaaataac 250

 tttcaccctt gcaaggctga tagacggctc ttcattggtc tttttttatg 300

 gttttgtttt gtttttttaa gtcattggtc ttaaatctgt atggtgacaa 350

 atctatttga gtttgattga gactttcttg gactcctttg gacaagaggt 400

 cagagcacaa aggctagtca ccacttcttt gacttcttga ggtatgagcc 450

 aaaattttac ttttccattg atttaaagca gaatttttgg agatgctgtg 500

 ttctagttcc tgacggaatc ggtggtggtt gctgactttg acactttgga 550

 gagtgatgtg gggagttata tagaagggga aacactagtt taggtgtgag 600

 gagttctagt atgccacaaa ttagctgagg ctttagacga agcacaatat 650

 ttgagcatca atcttctcat ctatgagata gacctgtcag gattattgtg 700

 aaaattagat gagataagtt gaaagtacag tgcttggtaa acagttagca 750

 ctcaaatatt agttcttttt cactttaatt aagagcagac tttgaatggt 800

 ctgatgccaa gtgtagatcc ttaagagaca aaacaaagaa actttcctgg 850

 cttcaaagaa aagaactcca tttctgaaag ggtgccttaa aaggaattca 900

 tttgtctgat ccatcctttt gcctttgggc attactactg tcaccctcca 950

 tttctttaca aacttcaggc aaggtggtct ctctctctct cccaataggc 1000

 aattccaggg ttgtaaactc attatcagga agcttaatct tagaactgaa 1050

 atacctcaca gagcaattta aacctctttc ttcttgttcc tattcttcat 1100

 gggaagaaaa ctgggttgat ccctatcttc tttttaagga gccacatttg 1150

 ccatttatta ttgctctttt gcctatttaa aaaaaataac agtcagaaaa 1200

 aataatgatt attaaaatga tagtcattat ttacttagtg aatgtcagga 1250

 taggtattta ttactcttag cttcttattg gtatcagatg tagatcacgg 1300

 tcttactgtt gattaactct tcagttatat atacatactt tgattcttta 1350

 gttacataat tgataacaaa gtgtgcttct gaagaattat tctggctgta 1400

 tggctcttgt ttcctcccct tggtaaaaat ggaggcatga atctcagttt 1450

 tgtgatctgc ttttaatttc atatatgaca ttatttgata tacataatta 1500

 ccaacatcca aaagcgtttc ttcccctttc tacgtgtgca ctaaattcta 1550

 aaacaaaaat tggaatacaa aatgcctaat aaagaaaaaa ttcatgtaca 1600

 gaaaagcaaa agataatcta ctttgttaag ataatttgtc actagctggt 1650

 tgaataatgc acagtttttg tttaaggtta cacatttatg cctggattaa 1700

 ataacaatag taaaacttga caagtctttt gaaaaacagc tgctaaacat 1750

 attgctttct ggaatgtaat cattagcaac aaatattctc ttattctata 1800

 caattgcaga atgctagtgg aactttcttg taggttattt gacaatgaat 1850

 gttaattgat ttatttttta aaaatgtaaa atcctcttat ccctttaagg 1900

 ccggtttagg ctttcatgtc cctgtggtag aaaatttcaa atgctggctt 1950

 ctaatttcta ctcactgaag tgtcttccag acataccaga tggttggagc 2000

 tcctttgata gtatataagg gagctacata aatgtatttg aactaactcg 2050

 tgagcaaaat ttctgtttcc cgcaaaaaaa atctatgtcg ggtgcggaga 2100

 aagaggtaat gaaatg 2116

<210> 4647
<211> 23
<212> PRT
<213> Homo sapien

<400> 4647
 Pro Arg Glu Met Gly Trp Trp Val Thr Asp Ile Lys Gln Ser Thr
   1               5                  10                  15

 Arg Ser Ile Leu Glu Lys Tyr Gln
                  20

<210> 4648
<211> 5035
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 359-427
<223> Unknown base

<400> 4648
 ggtcgacgaa cacttacatg aagataatgg tgaagttgaa gtgcgtcgaa 50

 gttgtaggat tagaagtcgt tatagtggtg taaaccagtc catgctgttt 100

 gacaaactta taactaacac tgctgaagct gtacttcaaa aaatggatga 150

 catgaagaag atgcgtaggc agcgaatgag agaacttgaa gacttgggag 200

 tgtttaatga aacagaagaa agcaatctta atatgtacac aagaggaaaa 250

 cagaaagata ttcaaagaac tgatgaagaa acaactgata atcaagaagg 300

 cagtgtggag tcatctgaag agggtgaaga ccaagaacat gaagatgatg 350

 gtgaagatnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnngaa gaagatggag aagaagagaa 450

 tcagaagcga tattatctta gacagagaaa agctactgtt tactatcagg 500

 ctccattgga aaaacctcgt caccagagaa agcccaacat attttatagt 550

 ggcccagctt ctcctgcaag accaagatac cgattatctt ccgcaggacc 600

 aagaagtcct tactgtaaac gaatgaacag gcgaaggcat gcaatccaca 650

 gtagtgactc gacttcatct tcctcctctg aagatgaaca gcactttgag 700

 aggcggagga aaaggagtcg taatagggct atcaataggt gcctcccact 750

 aaattttcgg aaagatgaat taaaaggcat ttataaagat cgaatgaaaa 800

 ttggagcaag ccttgccgat gttgatccaa tgcaactaga ttcttcagta 850

 cgatttgata gtgttggtgg cctgtctaat catatagcag ctctaaaaga 900

 gatggtggtg tttccattac tttatccaga agtctttgaa aaatttaaaa 950

 ttcaaccccc aagaggttgt ttgttttatg ggccacctgg aactggaaag 1000

 actctggttg ccagagcact tgccaatgag tgcagtcaag gggataaaag 1050

 agtagcattt ttcatgagga aaggtgctga ttgtctaagt aaatgggtag 1100

 gagaatctga aagacagcta cgattgctgt ttgatcaggc ctatcagatg 1150

 cgcccatcaa ttattttttt tgacgaaatt gatggtctgg ctccagtacg 1200

 gtcaagcagg caagatcaga ttcacagttc tattgtttcc accctgctag 1250

 ctcttatgga tggattggac agcagagggg aaattgtggt cattggtgct 1300

 acgaacaggc tagattctat agatcctgct ttacgaaggc ctggtcgctt 1350

 tgatagagaa ttcctcttta gcctgcctga taaagaggct cgaaaagaga 1400

 ttctaaagat tcacaccagg gattggaatc ccaaaccact ggacacattt 1450

 ttagaagagc tagcagaaaa ctgtgttgga tactgtggag cagatattaa 1500

 atcaatatgt gctgaagctg ctttatgtgc tttacgacga cgctacccac 1550

 agatctatac cactagtgag aaactgcagt tggatctctc ttcaattaat 1600

 atctcagcta aggatttcga ggtagctatg caaaagatga taccagcctc 1650

 ccaaagagct gtgacatcac ctgggcaggc actgtccacc gttgtgaaac 1700

 cactcctgca aaacactgtt gacaagattt tagaagccct gcagagagta 1750

 tttccacatg cagaattcag aacaaataaa acattagact cagatatttc 1800

 ttgtcctctg ctagaaagtg acttggctta cagtgatgat gatgttccat 1850

 cagtttatga aaatggactt tctcagaaat cttctcataa ggcaaaagac 1900

 aattttaatt ttcttcattt gaatagaaat gcttgttacc aacctatgtc 1950

 ttttcgacca agaatattga tagtaggaga accaggattt gggcaaggtt 2000

 ctcacttggc accagctgtc attcatgctt tggaaaagtt tactgtatat 2050

 acattagaca ttcctgttct ttttggagtt agtactacat cccctgaaga 2100

 aacatgtgcc caggtgattc gtgaagctaa gagaacagca ccaagtatag 2150

 tgtatgttcc tcatatccac gtgtggtggg aaatagttgg accgacactt 2200

 aaagccacat ttaccacatt attacagaat attccttcat ttgctccagt 2250

 tttactactt gcaacttctg acaaacccca ttccgctttg ccagaagagg 2300

 tgcaagaatt gtttatccgt gattatggag agatttttaa tgtccagtta 2350

 ccggataaag aagaacggac aaaatttttt gaagatttaa ttctaaaaca 2400

 agctgctaag cctcctatat caaaaaagaa agcagttttg caggctttgg 2450

 aggtactccc agtagcacca ccacctgagc caagatcact gacagcagaa 2500

 gaagtgaaac gactagaaga acaagaagaa gatacattta gagaactgag 2550

 gattttctta agaaatgtta cacataggct tgctattgac aagcgattcc 2600

 gagtgtttac taagcctgtt gaccctgatg aggttcctga ttatgtcact 2650

 gtaataaagc aaccaatgga cctttcatct gtaatcagta aaattgatct 2700

 acacaagtat ctgactgtga aagactattt gagagatatt gatctaatct 2750

 gtagtaatgc cttagaatac aatccagata gagatcctgg agatcgtctt 2800

 attaggcata gagcctgtgc tttaagagat actgcctatg ccataattaa 2850

 agaagaactt gatgaagact ttgagcagct ctgtgaagaa attcaggaat 2900

 ctagaaagaa aagaggttgt agctcctcca aatatgcccc gtcttactac 2950

 catgtgatgc caaagcaaaa ttccactctt gttggtgata aaagatcaga 3000

 cccagagcag aatgaaaagc taaagacacc gagtactcct gtggcttgca 3050

 gcactcctgc tcagttgaag aggaaaattc gcaaaaagtc aaactggtac 3100

 ttaggcacca taaaaaagcg aaggaagatt tcacaggcaa aggatgatag 3150

 ccagaatgcc atagatcaca aaattgagag tgatacagag gaaactcaag 3200

 acacaagtgt agatcataat gagaccggaa acacaggaga gtcttcggtg 3250

 gaagaaaatg aaaaacagca aaatgcctct gaaagcaaac tggaattgag 3300

 aaataattca aatacttgta atatagagaa tgagcttgaa gactctagga 3350

 agactacagc atgtacagaa ttgagagaca agattgcttg taatggagat 3400

 gcttctagct ctcagataat acatatttct gatgaaaatg aaggaaaaga 3450

 aatgtgtgtt ctgcgaatga ctcgagctag acgttcccag gtagaacagc 3500

 agcagctcat cactgttgaa aaggctttgg caattctttc tcagcctaca 3550

 ccctcacttg ttgtggatca tgagcgatta aaaaatcttt tgaagactgt 3600

 tgttaaaaaa agtcaaaact acaacatatt tcagttggaa aatttgtatg 3650

 cagtaatcag ccaatgtatt tatcggcatc gcaaggacca tgataaaaca 3700

 tcacttattc agaaaatgga gcaagaggta gaaaacttca gttgttccag 3750

 atgatgatgt catggtatcg agtattcttt atattcagtt cctatttaag 3800

 tcatttttgt catgtccgcc taattgatgt agtatgaaac cctgcatctt 3850

 taaggaaaag attaaaatag taaaataaaa gtatttaaac tttcctgata 3900

 tttatgtaca tattaagata aatgtcatgt gtaagataac tgataaatat 3950

 tggaactttg ctagaacaag accctgtagt aatagtaata atagttgaag 4000

 tttggccaac tcttaataaa gttattttgg taactaatgt tttatggcac 4050

 ttaagaataa ttagcagcgt taaattttgt ttgtattaag cacttttaat 4100

 tttatccttc ctaaaaatag tttattgtat ctgacaagaa acttacttaa 4150

 ccattgtgtc cttcccatct tttttgtcat ctttgttttc ttcaaatgcc 4200

 ctcctcccat ctgccttgag attcccttgt cttcacttaa aagccagagt 4250

 gcaagtcatg atttgcggga gggctcttga accacttctg gctgcaccac 4300

 aattctgtac ttgagtatca cagtcattgt ttttgagaca aacattttta 4350

 taattctaat ttgggttaat aaagatttta aatatttctt ggtttacttt 4400

 tgtaattata tacacaacaa atgtattaat aactaccttg ttaaacacct 4450

 tttaatagca caaggttttt atatttgcaa gctgttgata tctttctaaa 4500

 actgtttagg ttatagtcta ttgatacttt ttatatacaa ttttataaat 4550

 ataaatatta taattttata ttaatggtac caaaaataca tttcttaagg 4600

 ttaaaagcat gcacttccat gcatacttgc ttttggggag agtggggaga 4650

 agacattcta ataatcagtt tgtgaaatag cttctgttgg aaaccttttg 4700

 aggggaataa ggaatggtca tctaaaatga gagattctgg attttaatgc 4750

 agttcaaagt tgagctgtat ttttgttgtt gatttatctg gatttttttt 4800

 aaagccttct aaaacccagt gaattcaata ccttaattag tacatactat 4850

 cttatgtaat gcataaagca atgccagtca ctgagaacat ttaaatatat 4900

 ttatattcct ggagatacac attctcattt ttgttggttt attataaatt 4950

 attcttctag atgcatcttt tataactagg atttcatttt gtgtgtatag 5000

 cttatgtaat aaattttaaa ggtgaaaact ctctt 5035

<210> 4649
<211> 1250
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 120-142
<223> unknown amino acid

<220>
<221> Unsure
<222> 359-427
<223> Unknown amino acid

<400> 4649
 Val Asp Glu His Leu His Glu Asp Asn Gly Glu Val Glu Val Arg
   1               5                  10                  15

 Arg Ser Cys Arg Ile Arg Ser Arg Tyr Ser Gly Val Asn Gln Ser
                  20                  25                  30

 Met Leu Phe Asp Lys Leu Ile Thr Asn Thr Ala Glu Ala Val Leu
                  35                  40                  45

 Gln Lys Met Asp Asp Met Lys Lys Met Arg Arg Gln Arg Met Arg
                  50                  55                  60

 Glu Leu Glu Asp Leu Gly Val Phe Asn Glu Thr Glu Glu Ser Asn
                  65                  70                  75

 Leu Asn Met Tyr Thr Arg Gly Lys Gln Lys Asp Ile Gln Arg Thr
                  80                  85                  90

 Asp Glu Glu Thr Thr Asp Asn Gln Glu Gly Ser Val Glu Ser Ser
                  95                 100                 105

 Glu Glu Gly Glu Asp Gln Glu His Glu Asp Asp Gly Glu Asp Xaa
                 110                 115                 120

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 125                 130                 135

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Glu Glu Asp Gly Glu Glu Glu Asn
                 140                 145                 150

 Gln Lys Arg Tyr Tyr Leu Arg Gln Arg Lys Ala Thr Val Tyr Tyr
                 155                 160                 165

 Gln Ala Pro Leu Glu Lys Pro Arg His Gln Arg Lys Pro Asn Ile
                 170                 175                 180

 Phe Tyr Ser Gly Pro Ala Ser Pro Ala Arg Pro Arg Tyr Arg Leu
                 185                 190                 195

 Ser Ser Ala Gly Pro Arg Ser Pro Tyr Cys Lys Arg Met Asn Arg
                 200                 205                 210

 Arg Arg His Ala Ile His Ser Ser Asp Ser Thr Ser Ser Ser Ser
                 215                 220                 225

 Ser Glu Asp Glu Gln His Phe Glu Arg Arg Arg Lys Arg Ser Arg
                 230                 235                 240

 Asn Arg Ala Ile Asn Arg Cys Leu Pro Leu Asn Phe Arg Lys Asp
                 245                 250                 255

 Glu Leu Lys Gly Ile Tyr Lys Asp Arg Met Lys Ile Gly Ala Ser
                 260                 265                 270

 Leu Ala Asp Val Asp Pro Met Gln Leu Asp Ser Ser Val Arg Phe
                 275                 280                 285

 Asp Ser Val Gly Gly Leu Ser Asn His Ile Ala Ala Leu Lys Glu
                 290                 295                 300

 Met Val Val Phe Pro Leu Leu Tyr Pro Glu Val Phe Glu Lys Phe
                 305                 310                 315

 Lys Ile Gln Pro Pro Arg Gly Cys Leu Phe Tyr Gly Pro Pro Gly
                 320                 325                 330

 Thr Gly Lys Thr Leu Val Ala Arg Ala Leu Ala Asn Glu Cys Ser
                 335                 340                 345

 Gln Gly Asp Lys Arg Val Ala Phe Phe Met Arg Lys Gly Ala Asp
                 350                 355                 360

 Cys Leu Ser Lys Trp Val Gly Glu Ser Glu Arg Gln Leu Arg Leu
                 365                 370                 375

 Leu Phe Asp Gln Ala Tyr Gln Met Arg Pro Ser Ile Ile Phe Phe
                 380                 385                 390

 Asp Glu Ile Asp Gly Leu Ala Pro Val Arg Ser Ser Arg Gln Asp
                 395                 400                 405

 Gln Ile His Ser Ser Ile Val Ser Thr Leu Leu Ala Leu Met Asp
                 410                 415                 420

 Gly Leu Asp Ser Arg Gly Glu Ile Val Val Ile Gly Ala Thr Asn
                 425                 430                 435

 Arg Leu Asp Ser Ile Asp Pro Ala Leu Arg Arg Pro Gly Arg Phe
                 440                 445                 450

 Asp Arg Glu Phe Leu Phe Ser Leu Pro Asp Lys Glu Ala Arg Lys
                 455                 460                 465

 Glu Ile Leu Lys Ile His Thr Arg Asp Trp Asn Pro Lys Pro Leu
                 470                 475                 480

 Asp Thr Phe Leu Glu Glu Leu Ala Glu Asn Cys Val Gly Tyr Cys
                 485                 490                 495

 Gly Ala Asp Ile Lys Ser Ile Cys Ala Glu Ala Ala Leu Cys Ala
                 500                 505                 510

 Leu Arg Arg Arg Tyr Pro Gln Ile Tyr Thr Thr Ser Glu Lys Leu
                 515                 520                 525

 Gln Leu Asp Leu Ser Ser Ile Asn Ile Ser Ala Lys Asp Phe Glu
                 530                 535                 540

 Val Ala Met Gln Lys Met Ile Pro Ala Ser Gln Arg Ala Val Thr
                 545                 550                 555

 Ser Pro Gly Gln Ala Leu Ser Thr Val Val Lys Pro Leu Leu Gln
                 560                 565                 570

 Asn Thr Val Asp Lys Ile Leu Glu Ala Leu Gln Arg Val Phe Pro
                 575                 580                 585

 His Ala Glu Phe Arg Thr Asn Lys Thr Leu Asp Ser Asp Ile Ser
                 590                 595                 600

 Cys Pro Leu Leu Glu Ser Asp Leu Ala Tyr Ser Asp Asp Asp Val
                 605                 610                 615

 Pro Ser Val Tyr Glu Asn Gly Leu Ser Gln Lys Ser Ser His Lys
                 620                 625                 630

 Ala Lys Asp Asn Phe Asn Phe Leu His Leu Asn Arg Asn Ala Cys
                 635                 640                 645

 Tyr Gln Pro Met Ser Phe Arg Pro Arg Ile Leu Ile Val Gly Glu
                 650                 655                 660

 Pro Gly Phe Gly Gln Gly Ser His Leu Ala Pro Ala Val Ile His
                 665                 670                 675

 Ala Leu Glu Lys Phe Thr Val Tyr Thr Leu Asp Ile Pro Val Leu
                 680                 685                 690

 Phe Gly Val Ser Thr Thr Ser Pro Glu Glu Thr Cys Ala Gln Val
                 695                 700                 705

 Ile Arg Glu Ala Lys Arg Thr Ala Pro Ser Ile Val Tyr Val Pro
                 710                 715                 720

 His Ile His Val Trp Trp Glu Ile Val Gly Pro Thr Leu Lys Ala
                 725                 730                 735

 Thr Phe Thr Thr Leu Leu Gln Asn Ile Pro Ser Phe Ala Pro Val
                 740                 745                 750

 Leu Leu Leu Ala Thr Ser Asp Lys Pro His Ser Ala Leu Pro Glu
                 755                 760                 765

 Glu Val Gln Glu Leu Phe Ile Arg Asp Tyr Gly Glu Ile Phe Asn
                 770                 775                 780

 Val Gln Leu Pro Asp Lys Glu Glu Arg Thr Lys Phe Phe Glu Asp
                 785                 790                 795

 Leu Ile Leu Lys Gln Ala Ala Lys Pro Pro Ile Ser Lys Lys Lys
                 800                 805                 810

 Ala Val Leu Gln Ala Leu Glu Val Leu Pro Val Ala Pro Pro Pro
                 815                 820                 825

 Glu Pro Arg Ser Leu Thr Ala Glu Glu Val Lys Arg Leu Glu Glu
                 830                 835                 840

 Gln Glu Glu Asp Thr Phe Arg Glu Leu Arg Ile Phe Leu Arg Asn
                 845                 850                 855

 Val Thr His Arg Leu Ala Ile Asp Lys Arg Phe Arg Val Phe Thr
                 860                 865                 870

 Lys Pro Val Asp Pro Asp Glu Val Pro Asp Tyr Val Thr Val Ile
                 875                 880                 885

 Lys Gln Pro Met Asp Leu Ser Ser Val Ile Ser Lys Ile Asp Leu
                 890                 895                 900

 His Lys Tyr Leu Thr Val Lys Asp Tyr Leu Arg Asp Ile Asp Leu
                 905                 910                 915

 Ile Cys Ser Asn Ala Leu Glu Tyr Asn Pro Asp Arg Asp Pro Gly
                 920                 925                 930

 Asp Arg Leu Ile Arg His Arg Ala Cys Ala Leu Arg Asp Thr Ala
                 935                 940                 945

 Tyr Ala Ile Ile Lys Glu Glu Leu Asp Glu Asp Phe Glu Gln Leu
                 950                 955                 960

 Cys Glu Glu Ile Gln Glu Ser Arg Lys Lys Arg Gly Cys Ser Ser
                 965                 970                 975

 Ser Lys Tyr Ala Pro Ser Tyr Tyr His Val Met Pro Lys Gln Asn
                 980                 985                 990

 Ser Thr Leu Val Gly Asp Lys Arg Ser Asp Pro Glu Gln Asn Glu
                 995                1000                1005

 Lys Leu Lys Thr Pro Ser Thr Pro Val Ala Cys Ser Thr Pro Ala
                1010                1015                1020

 Gln Leu Lys Arg Lys Ile Arg Lys Lys Ser Asn Trp Tyr Leu Gly
                1025                1030                1035

 Thr Ile Lys Lys Arg Arg Lys Ile Ser Gln Ala Lys Asp Asp Ser
                1040                1045                1050

 Gln Asn Ala Ile Asp His Lys Ile Glu Ser Asp Thr Glu Glu Thr
                1055                1060                1065

 Gln Asp Thr Ser Val Asp His Asn Glu Thr Gly Asn Thr Gly Glu
                1070                1075                1080

 Ser Ser Val Glu Glu Asn Glu Lys Gln Gln Asn Ala Ser Glu Ser
                1085                1090                1095

 Lys Leu Glu Leu Arg Asn Asn Ser Asn Thr Cys Asn Ile Glu Asn
                1100                1105                1110

 Glu Leu Glu Asp Ser Arg Lys Thr Thr Ala Cys Thr Glu Leu Arg
                1115                1120                1125

 Asp Lys Ile Ala Cys Asn Gly Asp Ala Ser Ser Ser Gln Ile Ile
                1130                1135                1140

 His Ile Ser Asp Glu Asn Glu Gly Lys Glu Met Cys Val Leu Arg
                1145                1150                1155

 Met Thr Arg Ala Arg Arg Ser Gln Val Glu Gln Gln Gln Leu Ile
                1160                1165                1170

 Thr Val Glu Lys Ala Leu Ala Ile Leu Ser Gln Pro Thr Pro Ser
                1175                1180                1185

 Leu Val Val Asp His Glu Arg Leu Lys Asn Leu Leu Lys Thr Val
                1190                1195                1200

 Val Lys Lys Ser Gln Asn Tyr Asn Ile Phe Gln Leu Glu Asn Leu
                1205                1210                1215

 Tyr Ala Val Ile Ser Gln Cys Ile Tyr Arg His Arg Lys Asp His
                1220                1225                1230

 Asp Lys Thr Ser Leu Ile Gln Lys Met Glu Gln Glu Val Glu Asn
                1235                1240                1245

 Phe Ser Cys Ser Arg
                1250

<210> 4650
<211> 4731
<212> DNA
<213> Homo sapien

<400> 4650
 cccagctgga ggaagcggcg gcggcggcca cgatgagtgc gggcgacgca 50

 gtgtgcaccg gctggctcgt taagtcgccc cccgagagga agctacagcg 100

 ctacgcctgg cgcaagcgct ggtttgtcct ccggcgaggc cgcatgagcg 150

 gcaaccccga tgtcttggag tactacagga acaagcactc cagcaagccc 200

 atccgggtga tagacctcag cgagtgtgca gtgtggaagc atgtgggccc 250

 cagctttgtt cggaaggaat ttcagaataa tttcgtgttc attgtcaaga 300

 ctacttcccg tacattctac ctggtggcca aaactgagca agaaatgcag 350

 gtgtgggtgc acagcatcag tcaggtctgc aaccttggcc acctggagga 400

 tggtgcagat tccatggaga gcctctctta cacgccctcc tccctgcagc 450

 catcctctgc cagctccctt cttaccgccc atgctgccag ctcctctttg 500

 ccaagagatg acccaaacac taatgccgta gccactgagg aaaccagaag 550

 tgagtcagag cttctcttcc ttccagatta tctggttttg tccaactgcg 600

 agactggaag actgcaccat accagtctac ccaccagatg tgatagctgg 650

 tcaaactcag accgttcatt ggaacaggct tcatttgatg atgtttttgt 700

 tgactgcctg cagccgctcc cctccagtca tttggtccac ccctcatgcc 750

 atggcagtgg agctcaggag gtgccatcct cgaggcctca ggctgccctg 800

 atctggagta gagaaatcaa tgggccaccc agggaccact tgtcttcttc 850

 accattgctg gaaagttcct taagttccac cattcaggta gataaaaatc 900

 aaggttcctt accctgtgga gcaaaagaac tagacattat gtccaacact 950

 ccacctcccc gcccccctaa gccaagccat ctgtctgaac ggcgccaaga 1000

 ggagtggagt acacacagtg gtagcaagaa gccagaatgc actctggttc 1050

 caagaagaat ctccctctct ggtttagaca acatgagaac ctggaaagct 1100

 gatgtagaag gccaatcctt aagacaccga gacaagcggc ttagtttgaa 1150

 tttgccatgc aggttctccc cgatgtaccc cacagcttca gccagtatcg 1200

 aagacagcta tgtgcccatg agcccccagg ctggtgcctc tggtcttgga 1250

 ccccactgca gccctgatga ctacattcca atgaactcag gaagcatctc 1300

 aagcccgttg cctgagctgc ctgcaaacct ggaacctccc ccagtgaata 1350

 gagatctcaa gcctcagagg aaatcacggc cacctcctct ggacctgaga 1400

 aacctctcga tcatccggga acatgcatct cttaccagga cccgcactgt 1450

 gccttgcagt cgaaccagct ttctctctcc agaaagaaat ggtattaatt 1500

 ctgcaagatt ttttgctaat cctgtttcca gagaagacga agaaagctac 1550

 atcgaaatgg aggagcaccg aacagccagt tccctgagca gtggtgccct 1600

 tacgtggaca aagaaattca gcctagatta tttggccctg gacttcaatt 1650

 cagcatcacc agcccccatg cagcagaaac ttctcctttc agaagaacaa 1700

 agagtagact atgtccaagt ggatgagcag aagacacagg ctctccagag 1750

 cacaaaacag gagtggacgg atgaaaggca atccaaagta tgagaggtgc 1800

 gggcttgtgc catgtgtgaa acagggaagc ttggggctca gtttgagttt 1850

 tttctttttt tttttttttt gtccactaaa aacacactga tggtcaacac 1900

 aggtcaaaac caagagagaa tgtgtagttt tcaaggtctt ggccagaacc 1950

 tttaggaaag aagacctgtt tatacattga aggaagaaaa gaaggaagca 2000

 gttgccttcc ggagggggct ctgagagaat ctagcctccc ctctgtccta 2050

 ttggagcaaa gattggagtg agtgttgcca ccaacaggat tttatcgttt 2100

 gactccaata cctgaaattc tgacttctct cctgtgcttc aatgagaatg 2150

 ataaattatc ctagcaaagg ggcctctgga gaccatcttg ttccagcctc 2200

 tgaagacagt tgaggagatc aagcccagca atggtggcag aatcttactc 2250

 cacagacttc agcagactag tcatttcaat acccaaagaa agacaagtga 2300

 caggggcaat ggatctcagg ctctgagata agtatatcag atgacactgg 2350

 tggctctaag gatattgcaa ttaagcagct acctgtagcc aggtattctg 2400

 ctgctcttgg ccttttccca cgcatcgtct cgtgtcttct ccgaaagacc 2450

 ttggaagata ggcctggaag agactgttga tgccactttg aagaaaagaa 2500

 cactgagaac tagaggaggg aacactttgc ccaagattac tcacaaagcc 2550

 aagacccaga gtccagctta gagaatagag ttgttcaggc tgccaattgc 2600

 aagctcattc ctctacctca tacttcctct gaggattttg acaaaatgga 2650

 ttaattgggt gagccttgga gacatgtggg aaacacctgc agacacaaaa 2700

 tgagtagtca tcctgtctcc ctttcaatag ggatctgaac aggtgttttg 2750

 atacttgaaa gatgtgcatg tcaagtgagg gtttctttct gcgatgttca 2800

 actggaactc tcccatcagt agttacaatt agaaatacct actgatggtt 2850

 agtctgaagg ccattctcat ggtcacctat acagtgtgtt tccctgtgag 2900

 ctagcagaca caatgaccag gaaaaaacct atgaattcca ttcttaggtt 2950

 tcccagccaa ttgctccctt ctgctttaga agtgactagg tactgagagt 3000

 acaaacactc ccactttata atgaaggcgt catgtcaccc cttcctttac 3050

 aggtcctggg gtccaggaga cccagaatga aggtgtcagt tgggcatgaa 3100

 gtgttattta gtgtccattc ttgatccttc tgagcaccta cagctggaaa 3150

 ctaagcagat actggtcctg cattctgact gagattgtgt cttctttatg 3200

 aggatagatc aaattggcag tcaggcccat gatagtcagt gcagttgggg 3250

 cagttgtaga ctttgctaca ggatttcagg gtttccaatc accccacagg 3300

 taagtgaatg ccaaagtctt cttttttcag accatacaag aagtcatttt 3350

 gattttcaaa gaagccgttt tgattttcaa agaagcaggt tctggtgaca 3400

 ttattttctt ccttggacaa agtgggggga aatttctaag tattttaact 3450

 gagttcaggg tccttagtga gcctggacag agcaaggaga gggctcccca 3500

 ctccctaagc cccacagcca gttctgcatc accacacaca gccagagcct 3550

 gtgaggagct gccttcttcc ccatgtgact tgcaaagagt ctcaggcaag 3600

 aaaccagggc ttcaaactgc tagttcccat ggagggtagt tccctcgtgt 3650

 ggagcacttg tgttaggatc actgattatc tgacaaaggc tggtgcagaa 3700

 aaaaaattgt aggcccaagt gtcaagaacc acaccagatt ggagatagaa 3750

 aagaatagct gaaattatgt cagtggtgaa atgtcactcc attgacccac 3800

 cgaaaaaaga aaagaaatct gtttctacca aacatttcca gaaacgtatt 3850

 tatagcatga agaaacacac atgggtagtg tgacctgttt ggatgtgatt 3900

 acttaaaaat ggaatgctct gaataggcac tctctacatt aaaggtatgg 3950

 aaggcgatag gggtcagaat tttaaaaatt taattttgaa aaaggtgact 4000

 cacccctcat ttccagagtg taggcaatta tgtcctgctt tgataaaact 4050

 gctagaggat ggctatgcaa aagcataacg attcaaggaa acaaagtaca 4100

 ggtagttttt gagctgacag cagcaaaggc accataagtc aaaatattgg 4150

 ttttggtgga gatgatcgat gtgtgtgtgt gagagagagc tatgtttcta 4200

 accaagggcc taatgtttgt tacagaaatg atcccagaga cctacaagat 4250

 gtgggaatca gcataacagg gcaatgcagc aattaacccc acatcgtttt 4300

 ctgtagttcc tttttgtttc attttcttct gtctcacctc gttagaaaat 4350

 tcctcccagt caggggtcgt ccagtgcagg acgggggacc caagggtctc 4400

 aagcctgcaa gtccagaagg tgacaaaccc aggagcactg ggagttaagc 4450

 tttccttggg gagggaagag ccttgatgtc cagcacacag cctggctata 4500

 aagacacgaa gcgacctacc cactgtacag tccacttcac aggatcagct 4550

 gaatcatgac ctttaaaagt tccgagttga aactgaaggc tctcctcaga 4600

 cctggctttt tcctcagtcc ctgttcatac catctctgca cccacaatca 4650

 cactgatttt tcaaattcat tttgtttttg ctgtttcatt tctggcatta 4700

 ataaaagtct tataaggaaa aaaaaaaaaa a 4731

<210> 4651
<211> 586
<212> PRT
<213> Homo sapien

<400> 4651
 Met Ser Ala Gly Asp Ala Val Cys Thr Gly Trp Leu Val Lys Ser
   1               5                  10                  15

 Pro Pro Glu Arg Lys Leu Gln Arg Tyr Ala Trp Arg Lys Arg Trp
                  20                  25                  30

 Phe Val Leu Arg Arg Gly Arg Met Ser Gly Asn Pro Asp Val Leu
                  35                  40                  45

 Glu Tyr Tyr Arg Asn Lys His Ser Ser Lys Pro Ile Arg Val Ile
                  50                  55                  60

 Asp Leu Ser Glu Cys Ala Val Trp Lys His Val Gly Pro Ser Phe
                  65                  70                  75

 Val Arg Lys Glu Phe Gln Asn Asn Phe Val Phe Ile Val Lys Thr
                  80                  85                  90

 Thr Ser Arg Thr Phe Tyr Leu Val Ala Lys Thr Glu Gln Glu Met
                  95                 100                 105

 Gln Val Trp Val His Ser Ile Ser Gln Val Cys Asn Leu Gly His
                 110                 115                 120

 Leu Glu Asp Gly Ala Asp Ser Met Glu Ser Leu Ser Tyr Thr Pro
                 125                 130                 135

 Ser Ser Leu Gln Pro Ser Ser Ala Ser Ser Leu Leu Thr Ala His
                 140                 145                 150

 Ala Ala Ser Ser Ser Leu Pro Arg Asp Asp Pro Asn Thr Asn Ala
                 155                 160                 165

 Val Ala Thr Glu Glu Thr Arg Ser Glu Ser Glu Leu Leu Phe Leu
                 170                 175                 180

 Pro Asp Tyr Leu Val Leu Ser Asn Cys Glu Thr Gly Arg Leu His
                 185                 190                 195

 His Thr Ser Leu Pro Thr Arg Cys Asp Ser Trp Ser Asn Ser Asp
                 200                 205                 210

 Arg Ser Leu Glu Gln Ala Ser Phe Asp Asp Val Phe Val Asp Cys
                 215                 220                 225

 Leu Gln Pro Leu Pro Ser Ser His Leu Val His Pro Ser Cys His
                 230                 235                 240

 Gly Ser Gly Ala Gln Glu Val Pro Ser Ser Arg Pro Gln Ala Ala
                 245                 250                 255

 Leu Ile Trp Ser Arg Glu Ile Asn Gly Pro Pro Arg Asp His Leu
                 260                 265                 270

 Ser Ser Ser Pro Leu Leu Glu Ser Ser Leu Ser Ser Thr Ile Gln
                 275                 280                 285

 Val Asp Lys Asn Gln Gly Ser Leu Pro Cys Gly Ala Lys Glu Leu
                 290                 295                 300

 Asp Ile Met Ser Asn Thr Pro Pro Pro Arg Pro Pro Lys Pro Ser
                 305                 310                 315

 His Leu Ser Glu Arg Arg Gln Glu Glu Trp Ser Thr His Ser Gly
                 320                 325                 330

 Ser Lys Lys Pro Glu Cys Thr Leu Val Pro Arg Arg Ile Ser Leu
                 335                 340                 345

 Ser Gly Leu Asp Asn Met Arg Thr Trp Lys Ala Asp Val Glu Gly
                 350                 355                 360

 Gln Ser Leu Arg His Arg Asp Lys Arg Leu Ser Leu Asn Leu Pro
                 365                 370                 375

 Cys Arg Phe Ser Pro Met Tyr Pro Thr Ala Ser Ala Ser Ile Glu
                 380                 385                 390

 Asp Ser Tyr Val Pro Met Ser Pro Gln Ala Gly Ala Ser Gly Leu
                 395                 400                 405

 Gly Pro His Cys Ser Pro Asp Asp Tyr Ile Pro Met Asn Ser Gly
                 410                 415                 420

 Ser Ile Ser Ser Pro Leu Pro Glu Leu Pro Ala Asn Leu Glu Pro
                 425                 430                 435

 Pro Pro Val Asn Arg Asp Leu Lys Pro Gln Arg Lys Ser Arg Pro
                 440                 445                 450

 Pro Pro Leu Asp Leu Arg Asn Leu Ser Ile Ile Arg Glu His Ala
                 455                 460                 465

 Ser Leu Thr Arg Thr Arg Thr Val Pro Cys Ser Arg Thr Ser Phe
                 470                 475                 480

 Leu Ser Pro Glu Arg Asn Gly Ile Asn Ser Ala Arg Phe Phe Ala
                 485                 490                 495

 Asn Pro Val Ser Arg Glu Asp Glu Glu Ser Tyr Ile Glu Met Glu
                 500                 505                 510

 Glu His Arg Thr Ala Ser Ser Leu Ser Ser Gly Ala Leu Thr Trp
                 515                 520                 525

 Thr Lys Lys Phe Ser Leu Asp Tyr Leu Ala Leu Asp Phe Asn Ser
                 530                 535                 540

 Ala Ser Pro Ala Pro Met Gln Gln Lys Leu Leu Leu Ser Glu Glu
                 545                 550                 555

 Gln Arg Val Asp Tyr Val Gln Val Asp Glu Gln Lys Thr Gln Ala
                 560                 565                 570

 Leu Gln Ser Thr Lys Gln Glu Trp Thr Asp Glu Arg Gln Ser Lys
                 575                 580                 585

 Val


<210> 4652
<211> 2734
<212> DNA
<213> Homo sapien

<400> 4652
 cccgctcccc gcaggggtgg agcctgagcg aggagcccgc gagctctcct 50

 ctctcctctg gtctccgcgg atgacgagtg gctggataac atggagtcgg 100

 gcaagatggc gcctcccaag aacgctccga gagatgcctt ggtgatggca 150

 cagatcctga aggatatggg aatcacagag tatgaaccaa gggttataaa 200

 tcaaatgttg gaatttgctt tccgttatgt gactacaatt ctggatgatg 250

 caaaaattta ttcgagccat gctaagaaac ctaatgttga tgcagatgat 300

 gtgagactgg caatccagtg tcgtgctgac caatctttta cctctcctcc 350

 cccaagagat tttttactgg atatcgcaag gcagaaaaat caaacccctt 400

 tgccactgat taagccatat gcaggaccta gactgccacc tgatagatac 450

 tgcttaacag ctccaaacta taggctgaag tccttaatta aaaagggacc 500

 taaccaaggg agactagttc cacgattaag tgttggtgct gttagtagca 550

 aacctactac tcctactata gcaaccccac aaacggtgtc tgtcccaaat 600

 aaagttgcaa ctccaatgtc agtgacaagc caaagattta cggtgcagat 650

 tccaccttct cagtccacac ctgtcaaacc agttcctgca acaactgcag 700

 ttcaaaatgt tctgattaat ccttcaatga ttgggcccaa aaatattctt 750

 attaccacca acatggtttc gtcacagaac acagccaatg aagcaaaccc 800

 actgaagaga aaacatgaag atgatgatga caatgatatt atgtaaggaa 850

 tatagtctag tctagatgca tttcaaaagg aaagttggtt ttgagcccag 900

 tatactgaac tagaatattc tagatcttgt tttaccttaa aagactgaaa 950

 tgtagctgca gtatttttcg tcagttaaaa ctgttagatc tctttagtaa 1000

 acatacaaat gtgtttttca gtaggcttca attacaaaca gttaagtact 1050

 tgtttcttaa tagtttcatt aatgttgagt cctaatatgg caattctgtt 1100

 tttgagacac ttttctgcct tctatcactg atagtagcat ttaagtttca 1150

 gattctacag cctagtcagc agatttatct ttgacagcat aatttctgat 1200

 ctacatttaa atactacttt attttataag gtaatatagt tacttactgt 1250

 cactagctaa tttttttttt ttaccaaatc tctcaatata ggaaacattt 1300

 tttggaaagg atggatttag aggagagatt ctaaatccat tttggatgta 1350

 tttgtttctt tgacttcctt aacttccaaa ctcaactccc tttctagatc 1400

 ccattcattt tctgcacctc ccccataggc ttgtttctct ccattgctat 1450

 taaatgtaga aggccatacc tggaatttta aaaatattat tcctggtaat 1500

 acagctcagt gtcattttcc tatttttaaa acatgctcta catgcctaat 1550

 gtttcgtgat tcactttaac ctgatggttt gcatttgctg tttttcactc 1600

 ttatgtcaga gcagttgggt tttacccctt agtttttatg cctgttaagc 1650

 tttactgtgc ttttgacagg tagttttggg tcagttatat tcagttttag 1700

 tattgtattc caagttgata actcttccat gtttcacatt tctaaattta 1750

 acagagatgc tgtagcttaa aacatgtttt gataagtaat tacactggac 1800

 ctaggcaaaa ccactgaaga acaagtgttc ctttttacca catacatatt 1850

 atgttttgat cactgctgct tgagccccgc tattggtata attcagatca 1900

 tattagcttg ttgctgagga tgtcacatat aagacaggat caaacctgaa 1950

 agacactaat ggttcatcct ctataaggcc aacaaagaaa acaaattaat 2000

 gtgatgtaac ttgcatttat gtgcactctg cataggtttc ccaataatac 2050

 tgtaatgttg ctgaacacct ttccctgttt tccatttata cacatattaa 2100

 agtcatattg ggaaagatgg caaagctttt gagaatataa acacacctgt 2150

 tttgtttttc ttaagttcaa catacttttg tagaatttgt aaaataaatg 2200

 ttcgtatcat aattgagaat ttatagccaa ggatcctcaa aacagaagtt 2250

 tcatcttagg atagtgtttg atatatctaa gaaagtccag taacagagaa 2300

 gaaatgtctc aaatgtctcg tatcagtttt agtgtttttc agtattaggg 2350

 aaaggtaata taaaaacagg taaaatgtat aaaaatagac ctgatcaaca 2400

 tcataggaga taaatattca ttatatagca taggatatta ttacttgaat 2450

 gttctcaggg aggcagcaag tcagaaggcc taggttctag tcctagctcc 2500

 atcatttacc aactgtgtga ccttacttca cctcttagcc ttgttctcct 2550

 cactagcagt aggaaagtaa cacctaccct gcctacctca cagggctgtt 2600

 gtgagggttc aattggtata tgtgaaaatt ctttcagaat tgtaaaatgc 2650

 tatatgactg taaggaatta ttgcatttgt tccaaggtta ataaaaattt 2700

 gagcttaaaa aaaaaaaaaa aaaaaaaaaa aaaa 2734

<210> 4653
<211> 251
<212> PRT
<213> Homo sapien

<400> 4653
 Met Glu Ser Gly Lys Met Ala Pro Pro Lys Asn Ala Pro Arg Asp
   1               5                  10                  15

 Ala Leu Val Met Ala Gln Ile Leu Lys Asp Met Gly Ile Thr Glu
                  20                  25                  30

 Tyr Glu Pro Arg Val Ile Asn Gln Met Leu Glu Phe Ala Phe Arg
                  35                  40                  45

 Tyr Val Thr Thr Ile Leu Asp Asp Ala Lys Ile Tyr Ser Ser His
                  50                  55                  60

 Ala Lys Lys Pro Asn Val Asp Ala Asp Asp Val Arg Leu Ala Ile
                  65                  70                  75

 Gln Cys Arg Ala Asp Gln Ser Phe Thr Ser Pro Pro Pro Arg Asp
                  80                  85                  90

 Phe Leu Leu Asp Ile Ala Arg Gln Lys Asn Gln Thr Pro Leu Pro
                  95                 100                 105

 Leu Ile Lys Pro Tyr Ala Gly Pro Arg Leu Pro Pro Asp Arg Tyr
                 110                 115                 120

 Cys Leu Thr Ala Pro Asn Tyr Arg Leu Lys Ser Leu Ile Lys Lys
                 125                 130                 135

 Gly Pro Asn Gln Gly Arg Leu Val Pro Arg Leu Ser Val Gly Ala
                 140                 145                 150

 Val Ser Ser Lys Pro Thr Thr Pro Thr Ile Ala Thr Pro Gln Thr
                 155                 160                 165

 Val Ser Val Pro Asn Lys Val Ala Thr Pro Met Ser Val Thr Ser
                 170                 175                 180

 Gln Arg Phe Thr Val Gln Ile Pro Pro Ser Gln Ser Thr Pro Val
                 185                 190                 195

 Lys Pro Val Pro Ala Thr Thr Ala Val Gln Asn Val Leu Ile Asn
                 200                 205                 210

 Pro Ser Met Ile Gly Pro Lys Asn Ile Leu Ile Thr Thr Asn Met
                 215                 220                 225

 Val Ser Ser Gln Asn Thr Ala Asn Glu Ala Asn Pro Leu Lys Arg
                 230                 235                 240

 Lys His Glu Asp Asp Asp Asp Asn Asp Ile Met
                 245                 250

<210> 4654
<211> 8848
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 5780, 5782, 5784, 5786, 5788, 5790, 5796
<223> Unknown base

<400> 4654
 ctcgcaggag caacacgtga tgtgtctact tatcagggtg agagggggag 50

 agcgagactc cgagcgtgcg ggcgaggaag ctgggcgggg ggccgagacg 100

 ggggccggga cgacggctgg ggcgccgggg tcgccagctc ctcgcccacc 150

 tccctccctg tgggagaaga ggaggagggg aagtgactgc ggagttgatg 200

 aactttgcac atccagaaac gccattttga ttccttttcc ggaacaagtt 250

 tgcatctctc ctcggtctct ccctgaagcc caccggtccc caacgcatca 300

 tgccagggag ccaagcgtcc tgcccggccg taagttgctc cgactgtgtg 350

 ttccaggagt ggtggctctg aggtgtgacc ctgcccacgt ttgggcccag 400

 ccaggttcag ccccccaata aggagggcag cttgataaca caaagaaaac 450

 agtgtcaacg agtactacca agagaagaag acaagaggtc aacacagact 500

 cattttctac tccgtgtgaa tgatagctac agcaggggaa agtttcatag 550

 tctatcagtg ggtcagaaaa tggagtttta tagcagaggc ttcttagaag 600

 cttaaacccc tgtcccaatg acgtcaagtt cgcccgctgg cttggaaggt 650

 tcagacctat cttccatcaa caccatgatg tcggcggtca tgagtgtagg 700

 gaaggtcaca gagaatggcg ggagccccca ggggatcaag tccccctcga 750

 agcctccagg accaaatcgg attggcagaa ggaaccagga aacgaaagag 800

 gagaagtctt cctataactg ccccctgtgt gagaagattt gcactaccca 850

 gcaccagctg accatgcaca ttcgccagca caacacagac actggaggag 900

 ccgaccactc atgcagcatc tgcggaaagt cactgagctc ggccagctcc 950

 ctcgatcgcc acatgctggt gcactctggc gagaggcctt acaagtgcac 1000

 tgtgtgtggc cagtcattta ccaccaatgg gaacatgcac agacatatga 1050

 agatccatga gaaggaccct aacagtgcca cagccacagc ccctccatct 1100

 cctctgaaac gtaggcgatt gtcctccaag aggaaactga gtcacgatgc 1150

 cgagtcagag agagaagacc cagcaccagc taaaaagatg gtagaagacg 1200

 ggcagtcagg tgacttggag aagaaagctg atgaagtctt tcactgccca 1250

 gtatgtttca aggagtttgt ttgcaagtat ggactggaga cccacatgga 1300

 gacccattca gataacccac taagatgtga catttgttgt gtcacctttc 1350

 gaacacatcg aggactgctg cgtcacaacg cgcttgtcca caaacaactt 1400

 cccagggatg caatgggcag acctttcatg acagaacaac ccttcaattc 1450

 ctgctggctt ccacgactta ggattcacgg acttctcctg taggaagttt 1500

 cctcgcattt ctcaggcctg gtgcgaaaca acctgcggag gtgcatcagc 1550

 gagcaacacc gttttgtctg cgacacctgt gacaaggcgt tccccatgct 1600

 ctgctcactg gctctgcaca agcagaccca tgtggcggca gaccagggtc 1650

 aagaaaagcc gcaggccacg cccctgcctg gtgacgccct ggaccagaag 1700

 ggcttcctgg ccttgcttgg cctgcagcac accaaagacg tcaggcctgc 1750

 ccccgccgag gagcccctgc cggatgacaa ccaggcaatt cagctccaga 1800

 cactcaagtg tcagctacct caggaccccg gctgcaccaa cctgctgagc 1850

 ctgtcacctt tcgaagctgc ttccctaggc ggttctctca cagttctccc 1900

 cgcgaccaag gacagcataa agcacctgtc cctgcagccc ttccagaagg 1950

 gcttcatcat ccagcctgac agcagcattg tggtcaagcc catctctggc 2000

 gagtcggcca tcgagctggc agacatccag caaattctga agatggcagc 2050

 ctcggctccc cctcagatca gtcttccgcc cttctccaag gcccctgccg 2100

 ccccactgca ggcgatcttc aagcacatgc cccctctgaa gccaaagccc 2150

 ctggtcacac cacggacggt ggtggccacc tccacgcccc cgcctctcat 2200

 caacgcccag caggcttccc cgggctgtat cagccccagc ctgccgccac 2250

 cgcccctgaa gctcctcaaa ggctcagtgg aggcggcctc caacgcccac 2300

 ctgctgcagt ccaagtccgg gacccagccc cacgcggcca cgcggctctc 2350

 cctgcagcag ccgcgggcgg agctgccggg ccagcctgag atgaagacgc 2400

 agctggagca ggacagcatc atcgaggccc tgctgccgct gagcatggag 2450

 gccaagatca agcaggagat cacagagggg gaactcaagg ccttcatgac 2500

 agcgcccggc ggcaagaaga cgcccgccat gcgcaaggtg ctctacccct 2550

 gccgcttctg caaccaggtg tttgccttct cgggggtctt gcgtgcccac 2600

 gtgcgctccc acctgggcat ctcgccatac cagtgcaaca tctgcgacta 2650

 catcgccgcc gacaaggccg cgctcatccg ccacctgcgc acgcacagtg 2700

 gggagcggcc ctacatttgc aagatctgcc actacccctt cactgtcaaa 2750

 gccaactgcg agcggcacct gcgcaagaag cacctcaagg ccacccgcaa 2800

 ggatatcgag aagaacatcg agtatgtgag tagcagcgcg gccgagctgg 2850

 tggacgcctt ctgcgccccg gacaccgtgt gccggctgtg cggcgaggac 2900

 ctcaagcact atcgtgccct gcgcatccac atgcgcacgc actgcggccg 2950

 cggcctgggc gggggccaca agggccgcaa gcccttcgag tgcaaggagt 3000

 gcagcgccgc gttcgcggcc aagcgcaact gcatccacca catcctcaag 3050

 cagcacctgc acgtgcccga gcaggacatc gagagctacg tgctggccgc 3100

 cgacggcctg ggccccgcag aggcgccggc cgctgaggcg tcggggcgcg 3150

 gggaggacag tggctgcgct gcccttggtg actgcaagcc cctcactgcc 3200

 ttcctggaac cccagaacgg ctttcttcac aggggcccca cccagcctcc 3250

 acctccccat gtctcgatca agttggagcc cgccagtagc tttgcggtgg 3300

 acttcaatga gcccctggac ttctcgcaga agggcctggc cctggtccaa 3350

 gtgaagcagg aaaacatctc ctttctgagc ccttcttccc tggtccccta 3400

 tgactgctcc atggagccca tcgacctgtc catccccaag aacttcagga 3450

 aaggggacaa ggatttggcc actcccagcg aagccaagaa gcctgaggag 3500

 gaggcgggga gcagcgagca gccctctccc tgcccagcac ccggcccttc 3550

 tcttcctgta actttggggc ccagcggaat cctggaaagc cccatggccc 3600

 ctgctccggc ggccaccccg gaacccccag cacagcccct gcagggccct 3650

 gttcagctgg cggtcccaat ctactcctca gccctggtca gcagccctcc 3700

 actcgtgggc agctcagccc tcctgagtgg cacagccttg ctgcgtccac 3750

 tgcggcccaa gcccccgctg cttttgccaa agccccccgt gacagaagag 3800

 ctgcccccgc tggcctccat tgcccagatc atctcatctg tatcctcggc 3850

 ccccaccctg ctgaaaacca aggtggcgga cccagggccc gcaagcactg 3900

 gcagtaacac cacggcttca gacagcttag gaggttctgt ccccaaagcc 3950

 gccaccaccg ccacccccgc tgccaccaac agcccaaaag agtctagtga 4000

 gcctcccgct ccagccagca gcccagaggc tgcctctccc accgagcagg 4050

 gcccagcgcg gacgtcgaag aagaggggcc ggaaaagggg gatgaggagc 4100

 cgaccccgcg ccaacagcgg cggggtggac ctggactcca gcggggagtt 4150

 tgccagcatc gagaagatgc tggccaccac agacaccaac aagttcagtc 4200

 cgtttctgca gacagcggag gacaacactc aggatgaggt ggccggagcc 4250

 cctgccgacc accatgggcc cagtgatgaa gagcagggca gtcccccaga 4300

 agacaagctg ctgagggcca agcggaactc gtacaccaac tgcctgcaga 4350

 agatcacctg tccccactgt ccccgggttt tcccttgggc cagctcccta 4400

 cagaggcaca tgctcacaca cactgacagt cagtcggatg cggagactgc 4450

 agccgccgcg ggcgaagtgc tagacctcac ctcacgggac agagagcagc 4500

 cgtcggaggg cgccactgag ctccgccagg tcgcagggga tgcgcctgtg 4550

 gagcaggcca cggcggaaac ggcctcgcgc gtgcaccggg aagagcacgg 4600

 gcgtggggag agccatgagc cggaggagga gcatggcact gaggagagca 4650

 ctggggacgc cgacggcgga agaggacgcg tcgagcaacc agagcctgga 4700

 cctggacttc gccaccaagc tcatggactt caagctggcg gagggcgacg 4750

 gcgaggcagg cgccgggggc gcggcctcgc aggagcagaa gctcgcctgc 4800

 gacacctgtg ggaagagctt caagttcctg ggcaccctga gccgccaccg 4850

 gaaggcgcac ggccgccagg agcccaagga cgagaaggga gatggcgcca 4900

 gcactgcaga ggaggggccc cagcccgccc ctgaacagga ggagaagccc 4950

 cccgagaccc cggcagaggt ggtggagtcg gccccgggtg ccggggaggc 5000

 cccggcggaa aagctcgcgg aggagacgga gggcccctcc gacggggaga 5050

 gcgcggccga gaaaaggtcc tcagagaaga gcgacgatga caagaaacca 5100

 aagacagact cccccaaaag cgtggccagc aaggcagaca agaggaagaa 5150

 ggtctgcagc gtgtgcaaca agcggttctg gtcgctgcag gacctgaccc 5200

 ggcacatgcg ctcccacaca ggggaaaggc catacaaatg tcagacctgc 5250

 gagcgaacct tcaccttgaa gcacagcctg gttcgccacc agcggatcca 5300

 ccagaaagcc aggcatgcca aacaccacgg gaaggacagc gacaaggaag 5350

 agcggggtga ggaggacagc gagaatgagt ccacccacag cggcaacaac 5400

 gccgtctcag agaacgaggc tgagctggct cccaatgcca gcaaccacat 5450

 ggctgtcacc cggagccgga aggagggctt ggccagtgcc accaaggact 5500

 gcagccacag ggaggagaag gtcacggcag ggtggccgtc tgagcctggc 5550

 cagggtgacc ttaacccaga gagcccggcg gccctggggc aggacctgct 5600

 ggagccgcgc agcaagaggc ctgcccaccc aatcctggcc acagctgatg 5650

 gcgcctccca gctcgtgggg atggagtgac agcctcagtc cccctcagca 5700

 cagacaaaag ccagcagagc aaagcgtcta tacttcatgg ggtttcctca 5750

 gtgccctttg gctgttgagg agtgagagan ananananan agaganagag 5800

 agagacaagc aggagcgtgg ctgctcgctc agtgccatag ccttaccgca 5850

 gcctgcgcgg gaggccacag cccgtgccga ttccagtgcc ttaactactt 5900

 accggatccc tccatattat catgggtgtt gtatttttcc aaaatgactt 5950

 cttaaacaaa acaaatatta taatgatatt gtctggagag gacctcttca 6000

 tttgagcatt agcgttattt tgtattggtg tgtgtgagct tgttcttgtg 6050

 aatctgtgat agcaccgttt gttctgtgag ctggaaacag aaggaaaaaa 6100

 catacccttg ggtacccata gccaataact ggaagaaaat gatgtgaatt 6150

 tcatgtaaat gaccagagga aagatggata agatgataat ttcttaaata 6200

 gacattttcc ctttttcttt gtgcttcatg gtggagctgt catctggtcc 6250

 ttggtattac aggatgtggt tgatgaaggt ttccaatatg gtttcaggcc 6300

 aaaaccaggg aagattctag cttcagcctc atgtccattt ccagtctgtc 6350

 agcattagac atggtcactg ttcaagtttc aagacatcca ttcttaacta 6400

 tagagaagag tactcccctg gcgtcttaac ctatggaaaa catgcacgga 6450

 taggatatat ttgattgcct cctcttccct ttcagtatat gtattattaa 6500

 tattattatt attattatta ttattagttc atcagtttgc tgttctctgc 6550

 agtgagcaga atcaaatggg caatatttgt cctgggagac ctgtgccgca 6600

 cccaggtccc cgtgttaacg tgtgcctgcg gttgtggttg gcaccctcgg 6650

 gtggtagctc ttctactgta atgagacaag cctttcttct gtcactgcag 6700

 aatttagaag gggccgtgag cagtcttccc aagcatggtc caggagcagc 6750

 tcagagaggg tggagtgagg atgcatgcat ccagggaaca ggcatcaaga 6800

 agccagggcc gtgcctggag cactgcagag atgactttgg agaaagcaaa 6850

 gcagtgaccc agtgaccagg cacattactc gtgagcgagg tattcccagt 6900

 cttcctgcta agcctaatcc aagccttacc cagctgtgct actgtcattt 6950

 gcaaagcaag gaaatactac tactggtaat aaaactacac atgcaagatg 7000

 tcagataaga aataggttta tatttacctt cctgcgatgt ggggttggtg 7050

 cttgaagata aatgtgctgt ttctagtttc ttaaatagcc cacacccctg 7100

 gatgcaaaaa ggcagggtta tttttaccca tgagcatcct gtgcaggcaa 7150

 tagacttccc tcactgtctc cgcctgcagg gaggagaatg taccccactg 7200

 cacctgagct cctggtccct cagccaagac ctcaggggtc cccagccagc 7250

 ctgctgctgg ggacccctgt gcttgctgca gtgtatggag cctcttgcct 7300

 tcccctgggg aggcacccct gtaccccagc ttccttcccc tggccttttc 7350

 tggccccagt gctcctcctt tacatagact tgttcacaca gaaacgtgca 7400

 cgcccccttt tctccgccac ttcaccagtt tctgaaatcc aacctcccag 7450

 acttcacagg aagatagata ttcttgagat aatgaaaagt gatatcttcg 7500

 catacgaaag gaaaaaaggt tgaggtatat atgattttta actgtattag 7550

 gggtgtatga accagtttaa aaacgaggtt ttatttactg tagagatgaa 7600

 tgcaaatcag aaccaatgat cccttggcct acttagttaa aaccagttca 7650

 tacatccctt agggttttta ttattattat tattattatt acagttgtta 7700

 ttgttgtttt tgttgttatt attatttggg gtttcttgtg ttttttcttt 7750

 gcgactctcc acactaaact tgcaatattg tggggagaag ctgtgactaa 7800

 actctacgct gcggtgagat gtagcagtaa tcagctccca gcgacgtgtg 7850

 tagctggggc tgccgctcgc aataatcact attgatttaa agctttactt 7900

 agccttgatc tgtaccctcg tagtcaataa ggtcttgcca cattttatta 7950

 gtgaggtgga gaaacgtatt atttgtttgt tgtttttgcc cttcccccac 8000

 cccccaatat taaactgtga aatttgtgat ttgtttaaac tctgggtgaa 8050

 tcatagctta gtttgcatgt ccagctaatt tgtttctata cattttgttt 8100

 gattctcttt ctccttctct cagggctttt acaaaaaaat atatatatat 8150

 ggatcttctg aaaagttttt tgaggtgcaa gttttttctc ttgttttttt 8200

 ttcttttttt tttctcattg attaatggac atgatgctga gattcaatca 8250

 ctacatgaaa cacctggctg tgaaaacaaa acaacccaga gggctgtgtt 8300

 ccaagcagcg ctggggaagc tacgtaacag tcggatgcca gttttggaag 8350

 attcaccatg cgttctgacc ctctgttcgt ctctttcctc tcctctttct 8400

 tcaagaagga aattgatcct agtgatttca gcccatgcat taaacaggaa 8450

 acaataataa atttgtagaa ttcatatttt tctaaaggga acttaaaaac 8500

 tgctgctaca tgttatgtac aaaactggtt tatgccacat gaacagagaa 8550

 tcacaagttt ggttttggta ctttttgttc ctctttgtat tcagttgtat 8600

 agaacttcca aattcagaat gagaagaaag ctgttctgta tcaaaccatt 8650

 taagcaataa atgttatatt ttaaaagctg cagattgccg gtcacgtggc 8700

 cgtcctgtga ttttttgtga tcccatcccc aaacccacag cccacttggg 8750

 gcaggtccca ggtgtgcagt accattgggg ggagtcacag gtgcccagga 8800

 aagctcttgt cacccaggca gcatttttat ttgcgctgga ggctgtgg 8848

<210> 4655
<211> 1418
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 272
<223> unknown amino acid

<220>
<221> Unsure
<222> 5780, 5782, 5784, 5786, 5788, 5790, 5796
<223> Unknown amino acid

<400> 4655
 Met Ser Ala Val Met Ser Val Gly Lys Val Thr Glu Asn Gly Gly
   1               5                  10                  15

 Ser Pro Gln Gly Ile Lys Ser Pro Ser Lys Pro Pro Gly Pro Asn
                  20                  25                  30

 Arg Ile Gly Arg Arg Asn Gln Glu Thr Lys Glu Glu Lys Ser Ser
                  35                  40                  45

 Tyr Asn Cys Pro Leu Cys Glu Lys Ile Cys Thr Thr Gln His Gln
                  50                  55                  60

 Leu Thr Met His Ile Arg Gln His Asn Thr Asp Thr Gly Gly Ala
                  65                  70                  75

 Asp His Ser Cys Ser Ile Cys Gly Lys Ser Leu Ser Ser Ala Ser
                  80                  85                  90

 Ser Leu Asp Arg His Met Leu Val His Ser Gly Glu Arg Pro Tyr
                  95                 100                 105

 Lys Cys Thr Val Cys Gly Gln Ser Phe Thr Thr Asn Gly Asn Met
                 110                 115                 120

 His Arg His Met Lys Ile His Glu Lys Asp Pro Asn Ser Ala Thr
                 125                 130                 135

 Ala Thr Ala Pro Pro Ser Pro Leu Lys Arg Arg Arg Leu Ser Ser
                 140                 145                 150

 Lys Arg Lys Leu Ser His Asp Ala Glu Ser Glu Arg Glu Asp Pro
                 155                 160                 165

 Ala Pro Ala Lys Lys Met Val Glu Asp Gly Gln Ser Gly Asp Leu
                 170                 175                 180

 Glu Lys Lys Ala Asp Glu Val Phe His Cys Pro Val Cys Phe Lys
                 185                 190                 195

 Glu Phe Val Cys Lys Tyr Gly Leu Glu Thr His Met Glu Thr His
                 200                 205                 210

 Ser Asp Asn Pro Leu Arg Cys Asp Ile Cys Cys Val Thr Phe Arg
                 215                 220                 225

 Thr His Arg Gly Leu Leu Arg His Asn Ala Leu Val His Lys Gln
                 230                 235                 240

 Leu Pro Arg Asp Ala Met Gly Arg Pro Phe Met Thr Glu Gln Pro
                 245                 250                 255

 Phe Asn Ser Cys Trp Leu Pro Arg Leu Arg Ile His Gly Leu Leu
                 260                 265                 270

 Leu Xaa Glu Val Ser Ser His Phe Ser Gly Leu Val Arg Asn Asn
                 275                 280                 285

 Leu Arg Arg Cys Ile Ser Glu Gln His Arg Phe Val Cys Asp Thr
                 290                 295                 300

 Cys Asp Lys Ala Phe Pro Met Leu Cys Ser Leu Ala Leu His Lys
                 305                 310                 315

 Gln Thr His Val Ala Ala Asp Gln Gly Gln Glu Lys Pro Gln Ala
                 320                 325                 330

 Thr Pro Leu Pro Gly Asp Ala Leu Asp Gln Lys Gly Phe Leu Ala
                 335                 340                 345

 Leu Leu Gly Leu Gln His Thr Lys Asp Val Arg Pro Ala Pro Ala
                 350                 355                 360

 Glu Glu Pro Leu Pro Asp Asp Asn Gln Ala Ile Gln Leu Gln Thr
                 365                 370                 375

 Leu Lys Cys Gln Leu Pro Gln Asp Pro Gly Cys Thr Asn Leu Leu
                 380                 385                 390

 Ser Leu Ser Pro Phe Glu Ala Ala Ser Leu Gly Gly Ser Leu Thr
                 395                 400                 405

 Val Leu Pro Ala Thr Lys Asp Ser Ile Lys His Leu Ser Leu Gln
                 410                 415                 420

 Pro Phe Gln Lys Gly Phe Ile Ile Gln Pro Asp Ser Ser Ile Val
                 425                 430                 435

 Val Lys Pro Ile Ser Gly Glu Ser Ala Ile Glu Leu Ala Asp Ile
                 440                 445                 450

 Gln Gln Ile Leu Lys Met Ala Ala Ser Ala Pro Pro Gln Ile Ser
                 455                 460                 465

 Leu Pro Pro Phe Ser Lys Ala Pro Ala Ala Pro Leu Gln Ala Ile
                 470                 475                 480

 Phe Lys His Met Pro Pro Leu Lys Pro Lys Pro Leu Val Thr Pro
                 485                 490                 495

 Arg Thr Val Val Ala Thr Ser Thr Pro Pro Pro Leu Ile Asn Ala
                 500                 505                 510

 Gln Gln Ala Ser Pro Gly Cys Ile Ser Pro Ser Leu Pro Pro Pro
                 515                 520                 525

 Pro Leu Lys Leu Leu Lys Gly Ser Val Glu Ala Ala Ser Asn Ala
                 530                 535                 540

 His Leu Leu Gln Ser Lys Ser Gly Thr Gln Pro His Ala Ala Thr
                 545                 550                 555

 Arg Leu Ser Leu Gln Gln Pro Arg Ala Glu Leu Pro Gly Gln Pro
                 560                 565                 570

 Glu Met Lys Thr Gln Leu Glu Gln Asp Ser Ile Ile Glu Ala Leu
                 575                 580                 585

 Leu Pro Leu Ser Met Glu Ala Lys Ile Lys Gln Glu Ile Thr Glu
                 590                 595                 600

 Gly Glu Leu Lys Ala Phe Met Thr Ala Pro Gly Gly Lys Lys Thr
                 605                 610                 615

 Pro Ala Met Arg Lys Val Leu Tyr Pro Cys Arg Phe Cys Asn Gln
                 620                 625                 630

 Val Phe Ala Phe Ser Gly Val Leu Arg Ala His Val Arg Ser His
                 635                 640                 645

 Leu Gly Ile Ser Pro Tyr Gln Cys Asn Ile Cys Asp Tyr Ile Ala
                 650                 655                 660

 Ala Asp Lys Ala Ala Leu Ile Arg His Leu Arg Thr His Ser Gly
                 665                 670                 675

 Glu Arg Pro Tyr Ile Cys Lys Ile Cys His Tyr Pro Phe Thr Val
                 680                 685                 690

 Lys Ala Asn Cys Glu Arg His Leu Arg Lys Lys His Leu Lys Ala
                 695                 700                 705

 Thr Arg Lys Asp Ile Glu Lys Asn Ile Glu Tyr Val Ser Ser Ser
                 710                 715                 720

 Ala Ala Glu Leu Val Asp Ala Phe Cys Ala Pro Asp Thr Val Cys
                 725                 730                 735

 Arg Leu Cys Gly Glu Asp Leu Lys His Tyr Arg Ala Leu Arg Ile
                 740                 745                 750

 His Met Arg Thr His Cys Gly Arg Gly Leu Gly Gly Gly His Lys
                 755                 760                 765

 Gly Arg Lys Pro Phe Glu Cys Lys Glu Cys Ser Ala Ala Phe Ala
                 770                 775                 780

 Ala Lys Arg Asn Cys Ile His His Ile Leu Lys Gln His Leu His
                 785                 790                 795

 Val Pro Glu Gln Asp Ile Glu Ser Tyr Val Leu Ala Ala Asp Gly
                 800                 805                 810

 Leu Gly Pro Ala Glu Ala Pro Ala Ala Glu Ala Ser Gly Arg Gly
                 815                 820                 825

 Glu Asp Ser Gly Cys Ala Ala Leu Gly Asp Cys Lys Pro Leu Thr
                 830                 835                 840

 Ala Phe Leu Glu Pro Gln Asn Gly Phe Leu His Arg Gly Pro Thr
                 845                 850                 855

 Gln Pro Pro Pro Pro His Val Ser Ile Lys Leu Glu Pro Ala Ser
                 860                 865                 870

 Ser Phe Ala Val Asp Phe Asn Glu Pro Leu Asp Phe Ser Gln Lys
                 875                 880                 885

 Gly Leu Ala Leu Val Gln Val Lys Gln Glu Asn Ile Ser Phe Leu
                 890                 895                 900

 Ser Pro Ser Ser Leu Val Pro Tyr Asp Cys Ser Met Glu Pro Ile
                 905                 910                 915

 Asp Leu Ser Ile Pro Lys Asn Phe Arg Lys Gly Asp Lys Asp Leu
                 920                 925                 930

 Ala Thr Pro Ser Glu Ala Lys Lys Pro Glu Glu Glu Ala Gly Ser
                 935                 940                 945

 Ser Glu Gln Pro Ser Pro Cys Pro Ala Pro Gly Pro Ser Leu Pro
                 950                 955                 960

 Val Thr Leu Gly Pro Ser Gly Ile Leu Glu Ser Pro Met Ala Pro
                 965                 970                 975

 Ala Pro Ala Ala Thr Pro Glu Pro Pro Ala Gln Pro Leu Gln Gly
                 980                 985                 990

 Pro Val Gln Leu Ala Val Pro Ile Tyr Ser Ser Ala Leu Val Ser
                 995                1000                1005

 Ser Pro Pro Leu Val Gly Ser Ser Ala Leu Leu Ser Gly Thr Ala
                1010                1015                1020

 Leu Leu Arg Pro Leu Arg Pro Lys Pro Pro Leu Leu Leu Pro Lys
                1025                1030                1035

 Pro Pro Val Thr Glu Glu Leu Pro Pro Leu Ala Ser Ile Ala Gln
                1040                1045                1050

 Ile Ile Ser Ser Val Ser Ser Ala Pro Thr Leu Leu Lys Thr Lys
                1055                1060                1065

 Val Ala Asp Pro Gly Pro Ala Ser Thr Gly Ser Asn Thr Thr Ala
                1070                1075                1080

 Ser Asp Ser Leu Gly Gly Ser Val Pro Lys Ala Ala Thr Thr Ala
                1085                1090                1095

 Thr Pro Ala Ala Thr Asn Ser Pro Lys Glu Ser Ser Glu Pro Pro
                1100                1105                1110

 Ala Pro Ala Ser Ser Pro Glu Ala Ala Ser Pro Thr Glu Gln Gly
                1115                1120                1125

 Pro Ala Arg Thr Ser Lys Lys Arg Gly Arg Lys Arg Gly Met Arg
                1130                1135                1140

 Ser Arg Pro Arg Ala Asn Ser Gly Gly Val Asp Leu Asp Ser Ser
                1145                1150                1155

 Gly Glu Phe Ala Ser Ile Glu Lys Met Leu Ala Thr Thr Asp Thr
                1160                1165                1170

 Asn Lys Phe Ser Pro Phe Leu Gln Thr Ala Glu Asp Asn Thr Gln
                1175                1180                1185

 Asp Glu Val Ala Gly Ala Pro Ala Asp His His Gly Pro Ser Asp
                1190                1195                1200

 Glu Glu Gln Gly Ser Pro Pro Glu Asp Lys Leu Leu Arg Ala Lys
                1205                1210                1215

 Arg Asn Ser Tyr Thr Asn Cys Leu Gln Lys Ile Thr Cys Pro His
                1220                1225                1230

 Cys Pro Arg Val Phe Pro Trp Ala Ser Ser Leu Gln Arg His Met
                1235                1240                1245

 Leu Thr His Thr Asp Ser Gln Ser Asp Ala Glu Thr Ala Ala Ala
                1250                1255                1260

 Ala Gly Glu Val Leu Asp Leu Thr Ser Arg Asp Arg Glu Gln Pro
                1265                1270                1275

 Ser Glu Gly Ala Thr Glu Leu Arg Gln Val Ala Gly Asp Ala Pro
                1280                1285                1290

 Val Glu Gln Ala Thr Ala Glu Thr Ala Ser Arg Val His Arg Glu
                1295                1300                1305

 Glu His Gly Arg Gly Glu Ser His Glu Pro Glu Glu Glu His Gly
                1310                1315                1320

 Thr Glu Glu Ser Thr Gly Asp Ala Asp Gly Gly Arg Gly Arg Val
                1325                1330                1335

 Glu Gln Pro Glu Pro Gly Pro Gly Leu Arg His Gln Ala His Gly
                1340                1345                1350

 Leu Gln Ala Gly Gly Gly Arg Arg Arg Gly Arg Arg Arg Gly Arg
                1355                1360                1365

 Gly Leu Ala Gly Ala Glu Ala Arg Leu Arg His Leu Trp Glu Glu
                1370                1375                1380

 Leu Gln Val Pro Gly His Pro Glu Pro Pro Pro Glu Gly Ala Arg
                1385                1390                1395

 Pro Pro Gly Ala Gln Gly Arg Glu Gly Arg Trp Arg Gln His Cys
                1400                1405                1410

 Arg Gly Gly Ala Pro Ala Arg Pro
                1415

<210> 4656
<211> 5601
<212> DNA
<213> Homo sapien

<400> 4656
 ggcccggctg cgaggaggag gcggcggcgg cgcaggagga tgtacttggt 50

 ggcgggggac agggggttgg ccggctgcgg gcacctcctg gtctcgctgc 100

 tggggctgct gctgctgctg gcgcgctccg gcacccgggc gctggtctgc 150

 ctgccctgtg acgagtccaa gtgcgaggag cccaggaact gcccggggag 200

 catcgtgcag ggcgtctgcg gctgctgcta cacgtgcgcc agccagagga 250

 acgagagctg cggcggcacc ttcgggattt acggaacctg cgaccggggg 300

 ctgcgttgtg tcatccgccc cccgctcaat ggcgactccc tcaccgagta 350

 cgaagcgggc gtttgcgaag atgagaactg gactgatgac caactgcttg 400

 gttttaaacc atgcaatgaa aaccttattg ctggctgcaa tataatcaat 450

 gggaaatgtg aatgtaacac cattcgaacc tgcagcaatc cctttgagtt 500

 tccaagtcag gatatgtgcc tttcagcttt aaagagaatt gaagaagaga 550

 agccagattg ctccaaggcc cgctgtgaag tccagttctc tccacgttgt 600

 cctgaagatt ctgttctgat cgagggttat gctcctcctg gggagtgctg 650

 tcccttaccc agccgctgcg tgtgcaaccc cgcaggctgt ctgcgcaaag 700

 tctgccagcc gggaaacctg aacatactag tgtcaaaagc ctcagggaag 750

 ccgggagagt gctgtgacct ctatgagtgc aaaccagttt tcggcgtgga 800

 ctgcaggact gtggaatgcc ctcctgttca gcagaccgcg tgtcccccgg 850

 acagctatga aactcaagtc agactaactg cagatggttg ctgtactttg 900

 ccaacaagat gcgagtgtct ctctggctta tgtggtttcc ccgtgtgtga 950

 ggtgggatcc actccccgca tagtctctcg tggcgatggg acacctggaa 1000

 agtgctgtga tgtctttgaa tgtgttaatg atacaaagcc agcctgcgta 1050

 tttaacaatg tggaatatta tgatggagac atgtttcgaa tggacaactg 1100

 tcggttctgt cgatgccaag ggggcgttgc catctgcttc actgcccagt 1150

 gtggtgagat aaactgcgag aggtactacg tgcccgaagg agagtgctgc 1200

 ccagtgtgtg aagatccagt gtatcctttt aataatcccg ctggctgcta 1250

 tgccaatggc ctgatccttg cccacggaga ccggtggcgg gaagacgact 1300

 gcacattctg ccagtgcgtc aacggtgaac gccactgcgt tgcgaccgtc 1350

 tgcggacaga cctgcacaaa ccctgtgaaa gtgcctgggg agtgttgccc 1400

 tgtgtgcgaa gaaccaacca tcatcacagt tgatccacct gcatgtgggg 1450

 agttatcaaa ctgcactctg acagggaagg actgcattaa tggtttcaaa 1500

 cgcgatcaca atggttgtcg gacctgtcag tgcataaaca ccgaggaact 1550

 atgttcagaa cgtaaacaag gctgcacctt gaactgtccc ttcggtttcc 1600

 ttactgatgc ccaaaactgt gagatctgtg agtgccgccc aaggcccaag 1650

 aagtgcagac ccataatctg tgacaagtat tgtccacttg gattgctgaa 1700

 gaataagcac ggctgtgaca tctgtcgctg taagaaatgt ccagagctct 1750

 catgcagtaa gatctgcccc ttgggtttcc agcaggacag tcacggctgt 1800

 cttatctgca agtgcagaga ggcctctgct tcagctgggc cacccatcct 1850

 gtcgggcact tgtctcaccg tggatggtca tcatcataaa aatgaggaga 1900

 gctggcacga tgggtgccgg gaatgctact gtctcaatgg acgggaaatg 1950

 tgtgccctga tcacctgccc ggtgcctgcc tgtggcaacc ccaccattca 2000

 ccctggacag tgctgcccat catgtgcaga tgactttgtg gtgcagaagc 2050

 cagagctcag tactccctcc atttgccacg cccctggagg agaatacttt 2100

 gtggaaggag aaacgtggaa cattgactcc tgtactcagt gcacctgcca 2150

 cagcggacgg gtgctgtgtg agacagaggt gtgcccaccg ctgctctgcc 2200

 agaacccctc acgcacccag gattcctgct gcccacagtg tacagatcaa 2250

 ccttttcggc cttccttgtc ccgcaataac agcgtaccta attactgcaa 2300

 aaatgatgaa ggggatatat tcctggcagc tgagtcctgg aagcctgacg 2350

 tttgtaccag ctgcatctgc attgatagcg taattagctg tttctctgag 2400

 tcctgccctt ctgtatcctg tgaaagacct gtcttgagaa aaggccagtg 2450

 ttgtccctac tgcatagaag acacaattcc aaagaaggtg gtgtgccact 2500

 tcagtgggaa ggcctatgcc gacgaggagc ggtgggacct tgacagctgc 2550

 acccactgct actgcctgca gggccagacc ctctgctcga ccgtcagctg 2600

 cccccctctg ccctgtgttg agcccatcaa cgtggaagga agttgctgcc 2650

 caatgtgtcc agaaatgtat gtcccagaac caaccaatat acccattgag 2700

 aagacaaacc atcgaggaga ggttgacctg gaggttcccc tgtggcccac 2750

 gcctagtgaa aatgatatcg tccatctccc tagagatatg ggtcacctcc 2800

 aggtagatta cagagataac aggctgcacc caagtgaaga ttcttcactg 2850

 gactccattg cctcagttgt ggttcccata attatatgcc tctctattat 2900

 aatagcattc ctattcatca atcagaagaa acagtggata ccactgcttt 2950

 gctggtatcg aacaccaact aagccttctt ccttaaataa tcagctagta 3000

 tctgtggact gcaagaaagg aaccagagtc caggtggaca gttcccagag 3050

 aatgctaaga attgcagaac cagatgcaag attcagtggc ttctacagca 3100

 tgcaaaaaca gaaccatcta caggcagaca atttctacca aacagtgtga 3150

 agaaaggcaa ctaggatgag gtttcaaaag acggaagacg actaaatctg 3200

 ctctaaaaag taaactagaa tttgtgcact tgcttagtgg attgtattgg 3250

 attgtgactt gatgtacagc gctaagacct tactgggatg ggctctgtct 3300

 acagcaatgt gcagaacaag cattcccact tttcctcaag ataactgacc 3350

 aagtgttttc ttagaaccaa agtttttaaa gttgctaaga tatatttgcc 3400

 tgtaagatag ctgtagagat atttggggtg gggacagtga gtttggatgg 3450

 ggaaatgggt gggagggtgg tgttgggaag aaaaattggt cagcttggct 3500

 cggggagaaa cctggtaaca taaaagcagt tcagtggccc agaggttatt 3550

 tttttcctat tgctctgaag actgcactgg ttgctgcaaa gctcaggcct 3600

 gaatgagcag gaaacaaaaa aggccttgcg acccagctgc cataaccacc 3650

 ttagaactac cagacgagca catcagaacc ctttgacagc catcccaggt 3700

 ctaaagccac aagtttcttt tctatacagt cacaactgca gtaggcagtg 3750

 aggaagccag agaaatgcga tagcggcatt tctctaaagc gggttattaa 3800

 ggatatatac agttacactt tttgctgctt ttattttctt ccaagccaat 3850

 caatcagcca gttcctagca gagtcagcac atgaacaaga tctaagtcat 3900

 ttcttgatgt gagcactgga gctttttttt ttttacaacg tgacaggaag 3950

 aggagggaga gggtgacgaa caccaggcat ttccaggggc tatatttcac 4000

 tgtttgttgt tgctttgttc tgttatattg ttggttgttc atagtttttg 4050

 ttgaagctct agcttaagaa gaaacttttt ttaaaaagac tgtttgggga 4100

 ttctttttcc ttattatata ctgattctac aaaatagaaa ctacttcatt 4150

 ttaattgtat attattcaag cacctttgtt gaagctcaaa aaaaatgatg 4200

 cctctttaaa ctttagcaat tataggagta tttatgtaac tatcttatgc 4250

 ttcaaaaaac aaaagtattt gtgtgcatgt gtatataata tatatatata 4300

 catatatatt tatacacata caatttatgt tttcctgttg aatgtatttt 4350

 tatgagattt taaccagaac aaaggcagat aaacaggcat tccatagcag 4400

 tgcttttgat cacttacaaa ttttttgaat aacacaaaat ctcattctac 4450

 ctgcagttta attggaaaga tgtgtgtgtg agagtatgta tgtgtgtgtg 4500

 tgtgtgtgtg tgtgtgcgcg cgcacgcacg ccttgagcag tcagcattgc 4550

 acctgctatg gagaagggta ttcctttatt aaaatcttcc tcatttggat 4600

 ttgctttcag ttggttttca atttgctcac tggccagaga cattgatggc 4650

 agttcttatc tgcatcacta atcagctcct ggattttttt tttttttttt 4700

 tcaaacaatg gtttgaaaca actactggaa tattgtccac aataagctgg 4750

 aagtttgttg tagtatgcct caaatataac tgactgtata ctatagtggt 4800

 aacttttcaa acagccctta gcacttttat actaattaac ccatttgtgc 4850

 attgagtttt cttttaaaaa tgcttgttgt gaaagacaca gatacccagt 4900

 atgcttaacg tgaaaagaaa atgtgttctg ttttgtaaag gaactttcaa 4950

 gtattgttgt aaatacttgg acagaggttg ctgaacttta aaaaaaatta 5000

 atttattatt ataatgacct aatttattaa tctgaagatt aaccattttt 5050

 ttgtcttaga atatcaaaaa gaaaaagaaa aaggtgttct agctgtttgc 5100

 atcaaaggaa aaaaagattt attatcaagg ggcaatattt ttatcttttc 5150

 caaaataaat ttgttaatga tacattacaa aaatagattg acatcagcct 5200

 gattagtata aattttgttg gtaattaatc cattcctggc ataaaaagtc 5250

 tttatcaaaa aaaattgtag atgcttgctt tttgtttttt caatcatggc 5300

 catattatga aaatactaac aggatatagg acaaggtgta aattttttta 5350

 ttattatttt aaagatatga tttatcctga gtgctgtatc tattactctt 5400

 ttactttggt tcctgttgtg ctcttgtaaa agaaaaatat aatttcctga 5450

 agaataaaat agatatatgg cacttggagt gcatcatagt tctacagttt 5500

 gtttttgttt tcttcaaaaa agctgtaaga gaattatctg caacttgatt 5550

 cttggcagga aataaacatt ttgagttgaa atcaaaaaaa aaaaaaaaaa 5600

 a 5601

<210> 4657
<211> 1036
<212> PRT
<213> Homo sapien

<400> 4657
 Met Tyr Leu Val Ala Gly Asp Arg Gly Leu Ala Gly Cys Gly His
   1               5                  10                  15

 Leu Leu Val Ser Leu Leu Gly Leu Leu Leu Leu Leu Ala Arg Ser
                  20                  25                  30

 Gly Thr Arg Ala Leu Val Cys Leu Pro Cys Asp Glu Ser Lys Cys
                  35                  40                  45

 Glu Glu Pro Arg Asn Cys Pro Gly Ser Ile Val Gln Gly Val Cys
                  50                  55                  60

 Gly Cys Cys Tyr Thr Cys Ala Ser Gln Arg Asn Glu Ser Cys Gly
                  65                  70                  75

 Gly Thr Phe Gly Ile Tyr Gly Thr Cys Asp Arg Gly Leu Arg Cys
                  80                  85                  90

 Val Ile Arg Pro Pro Leu Asn Gly Asp Ser Leu Thr Glu Tyr Glu
                  95                 100                 105

 Ala Gly Val Cys Glu Asp Glu Asn Trp Thr Asp Asp Gln Leu Leu
                 110                 115                 120

 Gly Phe Lys Pro Cys Asn Glu Asn Leu Ile Ala Gly Cys Asn Ile
                 125                 130                 135

 Ile Asn Gly Lys Cys Glu Cys Asn Thr Ile Arg Thr Cys Ser Asn
                 140                 145                 150

 Pro Phe Glu Phe Pro Ser Gln Asp Met Cys Leu Ser Ala Leu Lys
                 155                 160                 165

 Arg Ile Glu Glu Glu Lys Pro Asp Cys Ser Lys Ala Arg Cys Glu
                 170                 175                 180

 Val Gln Phe Ser Pro Arg Cys Pro Glu Asp Ser Val Leu Ile Glu
                 185                 190                 195

 Gly Tyr Ala Pro Pro Gly Glu Cys Cys Pro Leu Pro Ser Arg Cys
                 200                 205                 210

 Val Cys Asn Pro Ala Gly Cys Leu Arg Lys Val Cys Gln Pro Gly
                 215                 220                 225

 Asn Leu Asn Ile Leu Val Ser Lys Ala Ser Gly Lys Pro Gly Glu
                 230                 235                 240

 Cys Cys Asp Leu Tyr Glu Cys Lys Pro Val Phe Gly Val Asp Cys
                 245                 250                 255

 Arg Thr Val Glu Cys Pro Pro Val Gln Gln Thr Ala Cys Pro Pro
                 260                 265                 270

 Asp Ser Tyr Glu Thr Gln Val Arg Leu Thr Ala Asp Gly Cys Cys
                 275                 280                 285

 Thr Leu Pro Thr Arg Cys Glu Cys Leu Ser Gly Leu Cys Gly Phe
                 290                 295                 300

 Pro Val Cys Glu Val Gly Ser Thr Pro Arg Ile Val Ser Arg Gly
                 305                 310                 315

 Asp Gly Thr Pro Gly Lys Cys Cys Asp Val Phe Glu Cys Val Asn
                 320                 325                 330

 Asp Thr Lys Pro Ala Cys Val Phe Asn Asn Val Glu Tyr Tyr Asp
                 335                 340                 345

 Gly Asp Met Phe Arg Met Asp Asn Cys Arg Phe Cys Arg Cys Gln
                 350                 355                 360

 Gly Gly Val Ala Ile Cys Phe Thr Ala Gln Cys Gly Glu Ile Asn
                 365                 370                 375

 Cys Glu Arg Tyr Tyr Val Pro Glu Gly Glu Cys Cys Pro Val Cys
                 380                 385                 390

 Glu Asp Pro Val Tyr Pro Phe Asn Asn Pro Ala Gly Cys Tyr Ala
                 395                 400                 405

 Asn Gly Leu Ile Leu Ala His Gly Asp Arg Trp Arg Glu Asp Asp
                 410                 415                 420

 Cys Thr Phe Cys Gln Cys Val Asn Gly Glu Arg His Cys Val Ala
                 425                 430                 435

 Thr Val Cys Gly Gln Thr Cys Thr Asn Pro Val Lys Val Pro Gly
                 440                 445                 450

 Glu Cys Cys Pro Val Cys Glu Glu Pro Thr Ile Ile Thr Val Asp
                 455                 460                 465

 Pro Pro Ala Cys Gly Glu Leu Ser Asn Cys Thr Leu Thr Gly Lys
                 470                 475                 480

 Asp Cys Ile Asn Gly Phe Lys Arg Asp His Asn Gly Cys Arg Thr
                 485                 490                 495

 Cys Gln Cys Ile Asn Thr Glu Glu Leu Cys Ser Glu Arg Lys Gln
                 500                 505                 510

 Gly Cys Thr Leu Asn Cys Pro Phe Gly Phe Leu Thr Asp Ala Gln
                 515                 520                 525

 Asn Cys Glu Ile Cys Glu Cys Arg Pro Arg Pro Lys Lys Cys Arg
                 530                 535                 540

 Pro Ile Ile Cys Asp Lys Tyr Cys Pro Leu Gly Leu Leu Lys Asn
                 545                 550                 555

 Lys His Gly Cys Asp Ile Cys Arg Cys Lys Lys Cys Pro Glu Leu
                 560                 565                 570

 Ser Cys Ser Lys Ile Cys Pro Leu Gly Phe Gln Gln Asp Ser His
                 575                 580                 585

 Gly Cys Leu Ile Cys Lys Cys Arg Glu Ala Ser Ala Ser Ala Gly
                 590                 595                 600

 Pro Pro Ile Leu Ser Gly Thr Cys Leu Thr Val Asp Gly His His
                 605                 610                 615

 His Lys Asn Glu Glu Ser Trp His Asp Gly Cys Arg Glu Cys Tyr
                 620                 625                 630

 Cys Leu Asn Gly Arg Glu Met Cys Ala Leu Ile Thr Cys Pro Val
                 635                 640                 645

 Pro Ala Cys Gly Asn Pro Thr Ile His Pro Gly Gln Cys Cys Pro
                 650                 655                 660

 Ser Cys Ala Asp Asp Phe Val Val Gln Lys Pro Glu Leu Ser Thr
                 665                 670                 675

 Pro Ser Ile Cys His Ala Pro Gly Gly Glu Tyr Phe Val Glu Gly
                 680                 685                 690

 Glu Thr Trp Asn Ile Asp Ser Cys Thr Gln Cys Thr Cys His Ser
                 695                 700                 705

 Gly Arg Val Leu Cys Glu Thr Glu Val Cys Pro Pro Leu Leu Cys
                 710                 715                 720

 Gln Asn Pro Ser Arg Thr Gln Asp Ser Cys Cys Pro Gln Cys Thr
                 725                 730                 735

 Asp Gln Pro Phe Arg Pro Ser Leu Ser Arg Asn Asn Ser Val Pro
                 740                 745                 750

 Asn Tyr Cys Lys Asn Asp Glu Gly Asp Ile Phe Leu Ala Ala Glu
                 755                 760                 765

 Ser Trp Lys Pro Asp Val Cys Thr Ser Cys Ile Cys Ile Asp Ser
                 770                 775                 780

 Val Ile Ser Cys Phe Ser Glu Ser Cys Pro Ser Val Ser Cys Glu
                 785                 790                 795

 Arg Pro Val Leu Arg Lys Gly Gln Cys Cys Pro Tyr Cys Ile Glu
                 800                 805                 810

 Asp Thr Ile Pro Lys Lys Val Val Cys His Phe Ser Gly Lys Ala
                 815                 820                 825

 Tyr Ala Asp Glu Glu Arg Trp Asp Leu Asp Ser Cys Thr His Cys
                 830                 835                 840

 Tyr Cys Leu Gln Gly Gln Thr Leu Cys Ser Thr Val Ser Cys Pro
                 845                 850                 855

 Pro Leu Pro Cys Val Glu Pro Ile Asn Val Glu Gly Ser Cys Cys
                 860                 865                 870

 Pro Met Cys Pro Glu Met Tyr Val Pro Glu Pro Thr Asn Ile Pro
                 875                 880                 885

 Ile Glu Lys Thr Asn His Arg Gly Glu Val Asp Leu Glu Val Pro
                 890                 895                 900

 Leu Trp Pro Thr Pro Ser Glu Asn Asp Ile Val His Leu Pro Arg
                 905                 910                 915

 Asp Met Gly His Leu Gln Val Asp Tyr Arg Asp Asn Arg Leu His
                 920                 925                 930

 Pro Ser Glu Asp Ser Ser Leu Asp Ser Ile Ala Ser Val Val Val
                 935                 940                 945

 Pro Ile Ile Ile Cys Leu Ser Ile Ile Ile Ala Phe Leu Phe Ile
                 950                 955                 960

 Asn Gln Lys Lys Gln Trp Ile Pro Leu Leu Cys Trp Tyr Arg Thr
                 965                 970                 975

 Pro Thr Lys Pro Ser Ser Leu Asn Asn Gln Leu Val Ser Val Asp
                 980                 985                 990

 Cys Lys Lys Gly Thr Arg Val Gln Val Asp Ser Ser Gln Arg Met
                 995                1000                1005

 Leu Arg Ile Ala Glu Pro Asp Ala Arg Phe Ser Gly Phe Tyr Ser
                1010                1015                1020

 Met Gln Lys Gln Asn His Leu Gln Ala Asp Asn Phe Tyr Gln Thr
                1025                1030                1035

 Val


<210> 4658
<211> 924
<212> DNA
<213> Homo sapien

<400> 4658
 cctcaaagag gaagcctacc gttgagttta gtaagatctt tgctacacac 50

 aatgtgatgc tggcagtggc aggggcagta atctttattt cgtcattttt 100

 gaaacataga agccgtaacg gaagcaagtg aaatgctcag tcttagacga 150

 ctgcgtcgtg ctatgaccgg actttttctt gaaaggggat gacagcatgg 200

 gaggcaatgg ctccacatgt aaacccgaca ctgaaagaca aggcactctc 250

 tccacagcag ccccaacaac tagccctgca ccctgtctct ctaaccacca 300

 caacaaaaaa catttaatcc ttgccttttg tgctggggtt ctactgacac 350

 tgctgctgat agcctttatc ttcctcatca taaagagcta cagaaaatat 400

 cactccaagc cccaggcccc agattcctca ctcagatcct ccagccaagc 450

 tttcatccat cccaggggaa tcacttacct atgccagcac aactttcaaa 500

 ctctcagaag atgctcaaat taaagtaaca aactaactca gcttttccaa 550

 tgaggcttga atccatttcc tctcatctca gccctatctt cacacatcac 600

 tttcactttt ttacaaattt tggaccacca cctgtgtgaa actgcagtcg 650

 gagttgttta gatgtgatct ggcaatgcta tccagcatct ttggagacca 700

 atggtcagtc ttttcctggc cagaggaaag attgatggcc ctcccacttg 750

 aactgacagc ctgtgagccc cttgggggca tagactgcct tccttggacc 800

 cttccaaagt gtgtggtaca gagctcagtg cacagagtat tcacccagca 850

 tcatgaatca acttgggagg agtcaaccaa atgaacaatc taccaaaaat 900

 ttcaaataaa gtcaaacccc ccac 924

<210> 4659
<211> 42
<212> PRT
<213> Homo sapien

<400> 4659
 Ser Lys Arg Lys Pro Thr Val Glu Phe Ser Lys Ile Phe Ala Thr
   1               5                  10                  15

 His Asn Val Met Leu Ala Val Ala Gly Ala Val Ile Phe Ile Ser
                  20                  25                  30

 Ser Phe Leu Lys His Arg Ser Arg Asn Gly Ser Lys
                  35                  40

<210> 4660
<211> 1828
<212> DNA
<213> Homo sapien

<400> 4660
 agatttttta aagataaaat accatctcta ctggacctgt ttagtggctc 50

 aggctgccct cacaggacat ccctgagacc accctgtcac tcttgatgtt 100

 ggaaccaggg cccaggcctg ctcctcattg tctcctgccc tcctagtccc 150

 caggagagga aaagaaatac tgttttagag aaataacatt ttcaacaaaa 200

 catccctgga gtcagatttt gagttggggt gggctaatca gggagtcggg 250

 gctctctgcg tgatgtcagt tctatggcta actggttttt ctaaaccagc 300

 cagctgccta tcaaaacagt acaacttttc taggaaatgc aattggcaaa 350

 gacacttacg atgctgagaa gtacacaagg tgaaactgct ccagtttttc 400

 tcatagcagg gtcagcagga aagcaagtgg tgcccctggc tcccatctca 450

 cacaggtgag actgcaccga gaggtaacgt ggccctcaca gcccaccacg 500

 cctggccttc gcccaattct gaaacttcgt aggatagagc tggaaagtgc 550

 cacatggtga agcgagatcc agctgtctgg gtggatgtcg gagtccatag 600

 gctgagcaga gatggttctt agtgaggttc tcgctgccag ttgacggtga 650

 aatcatagct gccatttaca ttttgtgaga ttatgaaaaa cataagacta 700

 aagaaactaa atgtgttatt cctgtggaca caaaaatgtg tgtttttcag 750

 atggggaggg gaccaaaaag gaaaaacatt tcatcttaaa actttcctaa 800

 gacaagggaa aacaaaaaac catgctctac aacttcaaat ttttcttaca 850

 aagaaaaatt taatattcga tgagaggttg aaccaggctt aaagcagaca 900

 tactaggaaa tggtgcagcc tgtaagaatg ccagtttgta agtactgact 950

 ttggaaaaga tcatcgcctc tatcagacac ttagggtcct ggtctggcaa 1000

 ttttggcctg atgtgatgcc acaagaccca acagagagag acacagagtc 1050

 caggataatg ttgacagtgg tgtagccctt taggagaaat ggcgctccct 1100

 gcggctggta ttaggttacc attggcaccg aaggaaccag gaggataaga 1150

 atatccataa tttcagagct gccctggcac agtacctgcc ccgtcggagg 1200

 ctctcactgg caaatgacag ctctgtgcaa ggagcactcc caagtataaa 1250

 aattattaca cagttttatt ctgaagaaca ttttgcattt taataaaaaa 1300

 ggatttatgt caggaaagag tcatttacaa accttgaagt gtttttgcct 1350

 ggatcagagt aagaatgtct taagaagagg tttgtaaggt cttcataaca 1400

 aagtggtgtt tgttatttac caaaaaaaaa aaaacacaca caatttaacg 1450

 ggttgtctgt atactattaa aaattttgga ccaaaattgc tacctatcat 1500

 ctatcttttt gattgcaggg aatccctgcc aaggtaactt gacagtcggc 1550

 ctaattctgt tgacagaaaa tgaagccttg acggttctaa ttatccaaaa 1600

 gtgggttttc atcaggacgt acagtcagag tgtgagtgca ttctaatgaa 1650

 aacttcttca gccctcattc aattgcatac aaaagccctc aaagagaaca 1700

 tacagtacag cagttttgta aaaggcaaca atacgatttg tacagacccc 1750

 gacactccaa tcctatagat caccacgttg ctcctctgtc cccagcaccc 1800

 cttatttctt aagcagcacc accagtcc 1828

<210> 4661
<211> 69
<212> PRT
<213> Homo sapien

<400> 4661
 Met Lys Asn Ile Arg Leu Lys Lys Leu Asn Val Leu Phe Leu Trp
   1               5                  10                  15

 Thr Gln Lys Cys Val Phe Phe Arg Trp Gly Gly Asp Gln Lys Gly
                  20                  25                  30

 Lys Thr Phe His Leu Lys Thr Phe Leu Arg Gln Gly Lys Thr Lys
                  35                  40                  45

 Asn His Ala Leu Gln Leu Gln Ile Phe Leu Thr Lys Lys Asn Leu
                  50                  55                  60

 Ile Phe Asp Glu Arg Leu Asn Gln Ala
                  65

<210> 4662
<211> 1370
<212> DNA
<213> Homo sapien

<400> 4662
 cttgcagtga gtttatcagc atactcaaaa tttttttcct ggaatttgga 50

 gggatgggag gagggggtgg ggcttacttg ttgtagcttt tttttttttt 100

 acagacttca cagagaatgc agttgtcttg acttcaggtc tgtctgttct 150

 gttggcaagt aaatgcagta ctgttctgat cccgctgcta ttagaatgca 200

 ttgtgaaacg actggagtat gattaaaagt tgtgttcccc aatgcttgga 250

 gtagtgattg ttgaaggaaa aaatccagct gagtgataaa ggctgagtgt 300

 tgaggaaatt tctgcagttt taagcagtcg tatttgtgat tgaagctgag 350

 tacattttgc tggtgtattt ttaggtaaaa tgctttttgt tcatttctgg 400

 tggtgggagg ggactgaagc ctttagtctt ttccagatgc aaccttaaaa 450

 tcagtgacaa gaaacattcc aaacaagcaa cagtcttcaa gaaattaaac 500

 tggcaagtgg aaatgtttaa acagttcagt gatctttagt gcattgttta 550

 tgtgtgggtt tctctctccc ctcccttggt cttaattctt acatgcagga 600

 acactcagca gacacacgta tgcgaagggc cagagaagcc agacccagta 650

 agaaaaaata gcctatttac tttaaataaa ccaaacattc cattttaaat 700

 gtggggattg ggaaccacta gttctttcag atggtattct tcagactata 750

 gaaggagctt ccagttgaat tcaccagtgg acaaaatgag gaaaacaggt 800

 gaacaagctt tttctgtatt tacatacaaa gtcagatcag ttatgggaca 850

 atagtattga atagatttca gctttatgct ggagtaactg gcatgtgagc 900

 aaactgtgtt ggcgtggggg tggaggggtg aggtgggcgc taagcctttt 950

 tttaagattt ttcaggtacc cctcactaaa ggcaccgaag gcttaaagta 1000

 ggacaaccat ggagccttcc tgtggcagga gagacaacaa agcgctctgc 1050

 ccctgcctag atgagtgtct tcctgtacat cctggcggcc cgggcctcct 1100

 gtgctgccca gcggcagggc tttgagaaga aaggtcctgt ctcgggcctg 1150

 cagccctcct tcgccgtcct cctgctgctg agcgccacgt ggctgctggc 1200

 actgctctct gtcaacagcg acaccctcct cttccactac ctctttgcta 1250

 cctgcaattg catccagggc cccttcatct tcctctccta tgtggtgctt 1300

 agcaaggagg tccggaaagc actcaagctt gcctgcagcc gcaagcccag 1350

 ccctgacctg ctctgaccac 1370

<210> 4663
<211> 101
<212> PRT
<213> Homo sapien

<400> 4663
 Met Ser Val Phe Leu Tyr Ile Leu Ala Ala Arg Ala Ser Cys Ala
   1               5                  10                  15

 Ala Gln Arg Gln Gly Phe Glu Lys Lys Gly Pro Val Ser Gly Leu
                  20                  25                  30

 Gln Pro Ser Phe Ala Val Leu Leu Leu Leu Ser Ala Thr Trp Leu
                  35                  40                  45

 Leu Ala Leu Leu Ser Val Asn Ser Asp Thr Leu Leu Phe His Tyr
                  50                  55                  60

 Leu Phe Ala Thr Cys Asn Cys Ile Gln Gly Pro Phe Ile Phe Leu
                  65                  70                  75

 Ser Tyr Val Val Leu Ser Lys Glu Val Arg Lys Ala Leu Lys Leu
                  80                  85                  90

 Ala Cys Ser Arg Lys Pro Ser Pro Asp Leu Leu
                  95                 100

<210> 4664
<211> 2661
<212> DNA
<213> Homo sapien

<400> 4664
 cagcagtagg ccttgcctca gatccaaggt cactcggaag aggccatgtc 50

 taccctcaat gacactcatg gaggaaatgc tgagagaagc attcagatgc 100

 atgacacaag gtaagactgc caaaaatctt gttcttgctc tcctcatttt 150

 gttatttgtt ttatttttag gagttttgag agcaaaatga caacacccag 200

 aaattcagta aatgggactt tcccggcaga gccaatgaaa ggccctattg 250

 ctatgcaatc tggtccaaaa ccactcttca ggaggatgtc ttcactggtg 300

 ggccccacgc aaagcttctt catgagggaa tctaagactt tgggggctgt 350

 ccagattatg aatgggctct tccacattgc cctggggggt cttctgatga 400

 tcccagcagg gatctatgca cccatctgtg tgactgtgtg gtaccctctc 450

 tggggaggca ttatgtatat tatttccgga tcactcctgg cagcaacgga 500

 gaaaaactcc aggaagtgtt tggtcaaagg aaaaatgata atgaattcat 550

 tgagcctctt tgctgccatt tctggaatga ttctttcaat catggacata 600

 cttaatatta aaatttccca ttttttaaaa atggagagtc tgaattttat 650

 tagagctcac acaccatata ttaacatata caactgtgaa ccagctaatc 700

 cctctgagaa aaactcccca tctacccaat actgttacag catacaatct 750

 ctgttcttgg gcattttgtc agtgatgctg atctttgcct tcttccagga 800

 acttgtaata gctggcatcg ttgagaatga atggaaaaga acgtgctcca 850

 gacccaaatc taacatagtt ctcctgtcag cagaagaaaa aaaagaacag 900

 actattgaaa taaaagaaga agtggttggg ctaactgaaa catcttccca 950

 accaaagaat gaagaagaca ttgaaattat tccaatccaa gaagaggaag 1000

 aagaagaaac agagacgaac tttccagaac ctccccaaga tcaggaatcc 1050

 tcaccaatag aaaatgacag ctctccttaa gtgatttctt ctgttttctg 1100

 tttccttttt taaacattag tgttcatagc ttccaagaga catgctgact 1150

 ttcatttctt gaggtactct gcacatacgc accacatctc tatctggcct 1200

 ttgcatggag tgaccatagc tccttctctc ttacattgaa tgtagagaat 1250

 gtagccattg tagcagcttg tgttgtcacg cttcttcttt tgagcaactt 1300

 tcttacactg aagaaaggca gaatgagtgc ttcagaatgt gatttcctac 1350

 taacctgttc cttggatagg ctttttagta tagtattttt ttttgtcatt 1400

 ttctccatca acaaccaggg agactgcacc tgatggaaaa gatatatgac 1450

 tgcttcatga cattcctaaa ctatcttttt tttattccac atctacgttt 1500

 ttggtggagt cccttttgca tcattgtttt aaggatgata aaaaaaaata 1550

 acaactaggg acaatacaga acccattcca tttatctttc tacagggctg 1600

 acattgtggc acattcttag agttaccaca ccccatgagg gaagctctaa 1650

 atagccaaca cccatctgtt ttttgtaaaa acagcatagc ttatacatgg 1700

 acatgtctct gccttaactt ttcctaactc ccactctagg ctattgtttg 1750

 catgtctacc tacttttagc cattatgcga gaaaagaaaa aaatgaccat 1800

 agaaaatgcc accatgaggt gcccaaattt caaataataa ttaacattta 1850

 gttatattta taatttccag atgacaaagt atttcatcaa ataacttcat 1900

 ttgatgttcc atgatcaaga aagaatccct atctctattt tacaagtaat 1950

 tcaaagaggc caaataactt gtaaacaaga aaaggtaact tgtcaacagt 2000

 cataactagt aattatgaga gccttgtttc ataaccaggt cttcttactc 2050

 aaatcctgtg atgtttgaaa taaccaaatt gtctctccaa tgtctgcata 2100

 aactgtgaga gccaagtcaa cagcttttat caagaattta ctctctgacc 2150

 agcaataaac aagcactgag agacacagag agccagattc agattttacc 2200

 catggggata aaaagactca gactttcacc acatttggaa aactacttgc 2250

 atcataaata tataataact ggtagtttat atgaagcaga cactaagtgc 2300

 tatagacact ctcagaatat catacttgga aacaatgtaa ttaaaatgcc 2350

 gaatctgagt caacagctgc cctacttttc aattcagata tactagtacc 2400

 ttacctagaa ataatgttaa cctagggtga agtcactata atctgtagtc 2450

 tattatttgg gcatttgcta catgatgagt gctgccagat tgtggcaggt 2500

 aaagagacaa tgtaatttgc actccctatg atatttctac atttttagcg 2550

 accactagtg gaagacattc cccaaaatta gaaaaaaagg agatagaaga 2600

 tttctgtcta tgtaaagttc tcaaaatttg ttctaaatta ataaaactat 2650

 ctttgtgttc a 2661

<210> 4665
<211> 297
<212> PRT
<213> Homo sapien

<400> 4665
 Met Thr Thr Pro Arg Asn Ser Val Asn Gly Thr Phe Pro Ala Glu
   1               5                  10                  15

 Pro Met Lys Gly Pro Ile Ala Met Gln Ser Gly Pro Lys Pro Leu
                  20                  25                  30

 Phe Arg Arg Met Ser Ser Leu Val Gly Pro Thr Gln Ser Phe Phe
                  35                  40                  45

 Met Arg Glu Ser Lys Thr Leu Gly Ala Val Gln Ile Met Asn Gly
                  50                  55                  60

 Leu Phe His Ile Ala Leu Gly Gly Leu Leu Met Ile Pro Ala Gly
                  65                  70                  75

 Ile Tyr Ala Pro Ile Cys Val Thr Val Trp Tyr Pro Leu Trp Gly
                  80                  85                  90

 Gly Ile Met Tyr Ile Ile Ser Gly Ser Leu Leu Ala Ala Thr Glu
                  95                 100                 105

 Lys Asn Ser Arg Lys Cys Leu Val Lys Gly Lys Met Ile Met Asn
                 110                 115                 120

 Ser Leu Ser Leu Phe Ala Ala Ile Ser Gly Met Ile Leu Ser Ile
                 125                 130                 135

 Met Asp Ile Leu Asn Ile Lys Ile Ser His Phe Leu Lys Met Glu
                 140                 145                 150

 Ser Leu Asn Phe Ile Arg Ala His Thr Pro Tyr Ile Asn Ile Tyr
                 155                 160                 165

 Asn Cys Glu Pro Ala Asn Pro Ser Glu Lys Asn Ser Pro Ser Thr
                 170                 175                 180

 Gln Tyr Cys Tyr Ser Ile Gln Ser Leu Phe Leu Gly Ile Leu Ser
                 185                 190                 195

 Val Met Leu Ile Phe Ala Phe Phe Gln Glu Leu Val Ile Ala Gly
                 200                 205                 210

 Ile Val Glu Asn Glu Trp Lys Arg Thr Cys Ser Arg Pro Lys Ser
                 215                 220                 225

 Asn Ile Val Leu Leu Ser Ala Glu Glu Lys Lys Glu Gln Thr Ile
                 230                 235                 240

 Glu Ile Lys Glu Glu Val Val Gly Leu Thr Glu Thr Ser Ser Gln
                 245                 250                 255

 Pro Lys Asn Glu Glu Asp Ile Glu Ile Ile Pro Ile Gln Glu Glu
                 260                 265                 270

 Glu Glu Glu Glu Thr Glu Thr Asn Phe Pro Glu Pro Pro Gln Asp
                 275                 280                 285

 Gln Glu Ser Ser Pro Ile Glu Asn Asp Ser Ser Pro
                 290                 295

<210> 4666
<211> 2353
<212> DNA
<213> Homo sapien

<400> 4666
 agcggctctc tctggccctc actcttactc tcttgcactc ttgctctccc 50

 cctccctccc ttactctaac agctgaatac acagtacttg ttgatgtacc 100

 aaaaaggcat tcaaccattt cgttattgat cgtcttttat ttcctttttt 150

 tatttttttt caaaataaca ctgctgtaat acatactggt gcttttattt 200

 atataggttg gattcccaga aatactatgt aggcatatgt ttcagaaata 250

 ttacaagatt actatccaaa atgaaagcgc ccgttccagc gtcctctcca 300

 gcactcttta atgcttgaaa atatgaaagg ctaaaaattg cattgtattg 350

 cttgttagtt taattgcctt ttgtctgagt tcaaagaggt ttgttgttgt 400

 tgctgtcctt gtttctgttt ggatttttct ctgatttgcc tgttcttacc 450

 ctttgctcat gtatctattg atgtttttca ttataaattt gtagaaattc 500

 ttactacata gtgcatatta atcatttgta gctctaatgt gttatgacgt 550

 tttcatcttg actttattga tgatatattt tcctttaaaa tttttaaact 600

 ttttaggtag acccttatct cttttataga ttttggtttc ctttttttat 650

 cacatggatg cccccaccca aagtcataca aatattcacc tacattttct 700

 tctaataact ttattatttt taatgtttaa atgtttgatc catctgaaat 750

 ttatttttgt atatggtgta agatggggat ccagctataa cattttgttc 800

 acattggata cctgattgtg acatttattt aaaatgttac ccattttcaa 850

 atttctgagc caatatcatg atttaattat agtggcttca tcgtaagttt 900

 tagaatccga taaagcaagt cccacttcat tagttttttt tttctttata 950

 taatatgtcc tagacattca ttttttcatg tgaaaaaatg aaatgcagaa 1000

 ttttaataaa attctaatta tgatggctga catcacaatt aaaatcctgc 1050

 atttttgttt agagggctct ttaataatat taaatcttag cactcaagag 1100

 tcttcgtaca tcattgaaat cttttggtct tgttattgga atattcttca 1150

 cgtaagtata tcatagctaa ctgaatttat ttctaagtat ttttacagtt 1200

 ttatttcata ttttgacatt gtgaattggt ttttttcttc tcatttgtaa 1250

 ttagctattt ttgacaatat agacaaccta tagatttttg tatttttatc 1300

 ttctgtctaa tgagcttatt taatcattga aattacagta gatttttaag 1350

 aatataatat tttgggtttt ctagatatga aattatttca cctggacata 1400

 tagatcattt tatttcctct taatgtttat actgattact gttacattag 1450

 ctggattttt caaaacaatg ttgaagagtg atgacagacg tgactgtctt 1500

 gttcttaatt ttcatggaag taagaatgca aaatattaat agggaatagt 1550

 attccctatt agtatgacat ttacttttgg ttattagtag gtagtcatta 1600

 acatgtttaa gagtttccgc tattcctgtt ttatagtgtt attgctagaa 1650

 gtggttcctg aattttataa aatgcctttt cagcatctat tgataaaatt 1700

 gtatgatttt ttttctcttt aatttgttga tgtaatgaat tagaatggta 1750

 ggcatttgat gtggaaccaa acttgtattt ctggaacaaa tactacttgg 1800

 tcattgtgaa ataatgattt gctacatgag tggattttat ttaccagtat 1850

 ttaatttaga attattgcat tttcattcca aagtaaaatt gtattttgtc 1900

 cttctgatgc tatctttatc aagttttgtt attgaagttg tgctagcttt 1950

 aaaaaaatat gaatatgtga gttttcaatt tttttcctgt ggtctggaat 2000

 aatttaaata gcattagaat tatttgtttg ttaaaagtta gctaggacaa 2050

 agtgtaaaac aatctaatcc tgatgacact tttaatagta gatttttaat 2100

 cagctttgtg atttctttaa tagttattgg tttattcagg ctttttatta 2150

 aaaaggtata tacattctct gtgacataca aagttaaaag ttctctatta 2200

 ttgctgattg tactggttgt tgcttgttga ctgtactatt cagatggctt 2250

 tatgcttttg tgtattttat gtcacctaga tctaattctg aaaacattgt 2300

 aataaaataa ttagctataa tggtaaaaaa aaaaagaaaa aaaaaaaaaa 2350

 aaa 2353

<210> 4667
<211> 58
<212> PRT
<213> Homo sapien

<400> 4667
 Arg Leu Ser Leu Ala Leu Thr Leu Thr Leu Leu His Ser Cys Ser
   1               5                  10                  15

 Pro Pro Pro Ser Leu Thr Leu Thr Ala Glu Tyr Thr Val Leu Val
                  20                  25                  30

 Asp Val Pro Lys Arg His Ser Thr Ile Ser Leu Leu Ile Val Phe
                  35                  40                  45

 Tyr Phe Leu Phe Leu Phe Phe Phe Lys Ile Thr Leu Leu
                  50                  55

<210> 4668
<211> 4266
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2862-3212
<223> Unknown base

<400> 4668
 catgggcgct gcagcagcta caaagacgac gccggctgcg ctcgcgggac 50

 cagagggagg gaggctgcgg acgagtgcgg ggaggagttt gagatgggag 100

 gcgcttgcag gggctccccc agttctgcgc tgtgagccgg ggcacaaaga 150

 gccctctgca ctagcgccgc aggaccgcgg acccgagttg gaggcatctg 200

 tccacccatg tggttccaga cacgttcatg tggccaccat gaccccgtcg 250

 gcatcacagg ggtaaccaag gtccacagaa cgaggggaaa gggtcactgt 300

 ggatcaagcc aggctcctct gagcagtcca gggtctattt acagagagca 350

 gcaagttcct gggacagagg agacagaagg gaatttccag gttcttcagg 400

 acgttcacaa ccacactgag aagcatcttt gcagataagt atttaaactt 450

 accagcccat agcctaccag cctgccctct tctggtctgt gcaggaaagt 500

 gtagtatcct agaatgccaa agtgggaggg gaaatgggtg atgtagctca 550

 ttctcttttc tacctctatg gaagaaagaa agagcctgtc cccattttgt 600

 ggggtcccag aaagggtgat tttcacactt cacatttggc attagggcta 650

 gtatttcaca aacattaccg tctggaactt ttgaaggctg agttaaatga 700

 cttcatcttg tgtacttgta gaactgctat tagaaggagg ctggggactc 750

 cctgatgatg tgaaccagcc cttctcttct cagttttagc actttgtgat 800

 catatttata aaccttggac agggctcctt ggccttagag ttaagtgaag 850

 agttaacact gtgactttag atgcattttt ctcagtgcaa gtgtctgagc 900

 tcatctccag ttctggactc gtgcccccac tcccgggtgc tgacagcaag 950

 ctctgaagat atgctgagag agctccctga ctctcctgac tcaggtctgc 1000

 cagttgatga agacagcaca gttgttacca aaaacaaaac ctggcagatg 1050

 gtcctaggtc aggattagtg gtcattctct ggtcttctcc agactggtga 1100

 cacagggtgg tcttaaaaga gtcctagtcc agcctctggc tccccgaatt 1150

 tcctctggtg catggggcat caggaaaggg caggggagaa ggagggggag 1200

 cagaaaaata actgaggctg ggcagaaggg tcccttccat ttcccatcca 1250

 ttgcttcaaa caatgggtga ttaccgtgca ccttgagtga atgtcaaggc 1300

 aggaagggtt ccagggccac ccagtgtggc aggagcagag ctgggatcag 1350

 aattctggat tcctgactct ccgttcagct gctattcagc tatcaccaag 1400

 ctgctgagtt tgtcctactt tctcctgggt cacattctgc tgttgttggg 1450

 aaacagggag tgagtgaagg gaacctggga acccttctcc cctcaccttt 1500

 taaggatgtt ctggggtgga ataaagagag gtggagggtg gggtgcctgg 1550

 gcccagcctc cctggctcct ggtccttctt tcttcagcag ggagttctgg 1600

 caaggcctgg gcctggggag ggggcctggg tgcagttttc tcctgcggtg 1650

 tggttggctc ttttgtcttc caggatgggc ctgtggggtc tgtgtgggga 1700

 aggaaggagc tgggagcctg ggctgcctgt gtgtcggctg gatgctgcca 1750

 ggtggctcca tctgggccgc atctccagga ctcctggcct ggacttctct 1800

 ttggacctcg ggtgaccttg gattctggcc acagtgactt agcggtcaga 1850

 ctccggtggt tttctagccc gctgggtgac tccctgaaga tctcatcctc 1900

 ttcacacctg ttgggatgga gcctcccatg gataggaact cttcctggtt 1950

 gatgctcagc agatgactga tctggctctg gaggacagct ccaggggtat 2000

 gagggaggcc tggcagccca ctactccctc ctcacctgct cgggccctgc 2050

 ctgctgggcc ctattgtctg ggtctggggg ccctttcctg ccccatgtga 2100

 acttgattcc tcctcgcgtt tctgtcggtg accagacaga gcctggcctg 2150

 ggccaagtcc ccactgacca cactttcccc aaggctgggt ctcaaaggac 2200

 cctacaggat ggggacagga acaaggatgg gagtcgggga ggggctgtca 2250

 ggcagagggc agatgcagct cctcgggtgc cgctggctgg agtcctttgt 2300

 ctccatttgc tcagtgcgta attgtcattt tgtgggggac ttccttggtg 2350

 gggcttttcc atgcttttcc tctccctgat ggttacaaag aggagacagt 2400

 caggatctgg gaggagctgg agccttcccc ctgtgctgtt gaactctggg 2450

 aggggcagcc agaggggctg agagtgcacc atcctgaaaa gagagggtct 2500

 ttaagagata agatttaggc tagggaaatt cactagaaag agacaggtgg 2550

 ccctgggttt tttttcctgc catccaaagg gaaccagtct tacccaaagg 2600

 cttaaggggt caccttagcc cagtctcagg acactcttct ccaatcagat 2650

 cgctgcttct agttgcactg ctcctggatt ctgttcttgg ggaacagaag 2700

 gtggcaggac aggccccaca atctgcaatt ccagctccct ccagagggga 2750

 cagtcccagc gtttgcaaga gagcagcttg tggcctccct taggcaagtt 2800

 taaaagccag atgtcctttt tcccagaatg cggagtggtg tgtactattc 2850

 atcagcttgg gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3050

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3100

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3150

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3200

 nnnnnnnnnn nnaggggaca ccattcagtt cttaacaggg tggtcaccgc 3250

 aaacatggaa agtcagagcc ttctcccctt cagaattccc gcccccaccc 3300

 agggatgggg aagaggagca gagaggtatg ggaagcagac acggagagtg 3350

 gcaggtacca tgctggggtg gctcaggagt gcttcggagg acatatggaa 3400

 ctggcagggc tcagtgcagg gaggcggagg ccctgggaga gccgtgtcct 3450

 gagaagggcc tgggctacaa ccctgggcaa gttacttcac ctctgagcct 3500

 ccgatgctct gtgaaatgga aggaatgtgc ttgcctgtca ggtgcaggga 3550

 gaattcagtg agattgtgtg cctagcacag tgcctgactc ccagtaggtg 3600

 ctcagcaaat gctcccatcc atctgggagt atagacttag ggtttatcta 3650

 tttttttttt ttggctctct ggactttaaa actcagcatc ttctgaacca 3700

 gaggcatttc tgattagccc ttccctacct attttcctag tatcactctt 3750

 taatcagctt ggggaggtgg cagcatttca tggcctccgt agtaactcac 3800

 aatgcttcct ggggtattta aattctactc tctcatcagc actgagcacc 3850

 tactttgggc cctttcccgt gctagccatt tgggggaaat ataggtgaag 3900

 agtggctggg gtttgaacct ttaggatttc acagccatgc tggatgggat 3950

 aaaaccagct cacatggaga atcagagaat gggacagtgc cacaaaacag 4000

 tctactgagg cacaagttct gagtgcctgg gaagtggtag agagacccca 4050

 gagagggctg ctgcagtctg gaacagcttc ctagcaagct gtaccaaaca 4100

 gggccttgaa ggatgagaaa gatctggctg agatgatacc cgaccctcta 4150

 gggaaattct tagagtaact tctaggaaat gtcattgctc ctttaaaaaa 4200

 aatctatgtc ggtgcggaga aagaggtaat gaaatggcag gaattcgata 4250

 tcagcttatc atacct 4266

<210> 4669
<211> 213
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 18-134
<223> unknown amino acid

<220>
<221> Unsure
<222> 2862-3212
<223> Unknown amino acid

<400> 4669
 Met Ser Phe Phe Pro Glu Cys Gly Val Val Cys Thr Ile His Gln
   1               5                  10                  15

 Leu Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 110                 115                 120

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Arg
                 125                 130                 135

 Gly His His Ser Val Leu Asn Arg Val Val Thr Ala Asn Met Glu
                 140                 145                 150

 Ser Gln Ser Leu Leu Pro Phe Arg Ile Pro Ala Pro Thr Gln Gly
                 155                 160                 165

 Trp Gly Arg Gly Ala Glu Arg Tyr Gly Lys Gln Thr Arg Arg Val
                 170                 175                 180

 Ala Gly Thr Met Leu Gly Trp Leu Arg Ser Ala Ser Glu Asp Ile
                 185                 190                 195

 Trp Asn Trp Gln Gly Ser Val Gln Gly Gly Gly Gly Pro Gly Arg
                 200                 205                 210

 Ala Val Ser


<210> 4670
<211> 3264
<212> DNA
<213> Homo sapien

<400> 4670
 tttgatgttt acattgcctc taactcggtg cctcagatac ctctgtgacc 50

 aaatttgtct ccaaccacat agctcatttc ctataatgtt atatcatagg 100

 aagccctcac agagacacta acacagctaa agatcttctg atattatcag 150

 caagggatgc aaggacttta ttggaatctg gagagtttaa ctgccttctc 200

 ttggtctcct cacttacttc ttaagaagtt ggcattacct gagactctta 250

 gctgtgatta ggtacaagct taccttttag ggtagaaaaa gaaagatcat 300

 ttgaaaaatg tatctaaaat aatccagaga acataatgtt tgtcttggtc 350

 tgataatgat aagaagtcaa ggattggcag agaaaatact aaacgccaag 400

 agttgagcct gtgggtctct ccataagagt tttaaaactc ttgccagtta 450

 ccactttatc caatttgcta tcattttcgt attatcagct atcgccctgt 500

 aaaatattca aaactagcta tttctaaagt aaacatttta tctgttactt 550

 ttaaccagat aggtgtcttt gtcatccttc tactataaat tgttctttgc 600

 caacctgtac aggtagatga accaggcgag agttttaatc agccttttct 650

 tgtccccttt gtaagaaaga gatgcttgcc atagagaagg acatgagtac 700

 attaaaaata atttaatagc cacaatatga tgttctttaa gctgcaaatt 750

 gagtacactg ggaatcaaca aatttgatga agcctgtctg tctcttcacc 800

 agtggagtga gtgcagcagt tagaaagaga agcaatattg tgcaactggt 850

 gcagtggtga gttaatcata gtgtataacc ttgtgttcat gaaacaggtg 900

 ttcattgttc tgcatctctc ttcatttaaa aaggatacac aattctttcc 950

 tcattgcata ttacaccaaa cgtttgaggg aaaaatcctc attcgtaaag 1000

 gattttggat ttataatcta aaactcaaca ataaagaaat aatattccaa 1050

 gtctctggtt tcctaagata cataataact gtttataaag aaggtctaag 1100

 agctgatatt tgccaaagtg atagaagagt tgttttttcc tctctactac 1150

 caagctttaa gacattaaaa gaagtctagt gtatttgaat attttagaga 1200

 aagctttatc attttttaag atgccaagat gctgcctacg tttgcaaaag 1250

 ttgtctaaga attcaccatg agctatattt tcttctggat ctttgaccaa 1300

 ggtgatgtca gcttatttct ggggaaggtg ttgagctctt atacatgaaa 1350

 atggatatag gctattctct gggatgagtg tcatttcaat gctttataaa 1400

 tccatgaagc tgcttgtctc ataaagtaga actgatacaa attttggttg 1450

 gatatataga gaattttata aatgtattgc cttagaattt ctgggtggag 1500

 acccaactac aatgacattg tcatgcaaga actataaaga taattagagt 1550

 taaaagttgt ttaaattgtg cccttaaata cagcagaacc tggagaaggt 1600

 catacttcaa aggtcgattt tgagtccgaa taaagaaaga cctagtaaca 1650

 gatagttttt ttttgttcat tttcttctac caagtagagg tttatgccct 1700

 cagaactaaa ctagtaaaaa tatctgaaca aaaaaccttt cgttgttggc 1750

 ataaaaatgt gatacactta gagacatttt gtttattgca tataaatcta 1800

 atttttccat aaattagatt tatgatattt tcataaagca cttgattagt 1850

 ttttcaaggc gtaccatcac aaagatgctt tcctgcagag ttctttgtat 1900

 caacagccta tggttgagat gttttctcat ttcctgtaga gagagaatac 1950

 cactaacaaa caagcaaaaa ctttagtgcc aaaatagtgg aactattttg 2000

 tcatcttttg agaaaaaaat atacaaagaa gtcatctttt cattaagtgg 2050

 attccctggt tcctttccag ctggttgtgg aagtaatggc taacatcctt 2100

 cagctgactt tgtctacaag gattattagc aaattctgta ggagcaagca 2150

 tgtctgacct taacttaatg gatcccttat tcaatcagtg gcttctgtct 2200

 ttatgtctgt tggcatatca aaatggtttc tgttcctaga aaagtaataa 2250

 catatgctta tctttattct ttttccaggt gattttgttt tcaaatgctc 2300

 cttgtgaaaa cacctagtgt tgtagaaagg aaagtggcca gaaagaacaa 2350

 cttgggacca tgagtaggtc attaaatagc ttagtgattt atcctcatat 2400

 agggcttata aaccctgtat gtgtttatat gtgcttcaca gagttcgtgt 2450

 caggctcaaa ggagatatgt ataagaaagt ggtttgtaaa ttatgttcca 2500

 tttcataaat agacactatt cacaaactaa aatctaataa aaaaccacag 2550

 ttgtaattta aactgcttga tataaaaaga ggtatcatag cagggaaaac 2600

 acactaattt tcatacagta gaggtattga aaactgaaaa tgggaaggca 2650

 acttgaagtc attgtatttg attgaaaatg tttaatacat ctcattattg 2700

 acaaaatatg tcatcttgta tttatttcaa ggaaaccaat gaattctagg 2750

 tagtatatta caagttggtc aaaatattcc atgtacaaat agggcttctg 2800

 tgtccatagc cttgtaagag atactgattg tatctgaaat tattttttaa 2850

 aaaaataaat tatcctgctt tagtgtgtta aaagtagacg atgttctaat 2900

 ataacactga agtgcttcat tgtatcccaa cagtttacct tcaagtaata 2950

 ttatctttat ttttaggcta agcacgtttg attattttgt ctgtctccta 3000

 tatagatctg ttttgtctag tgctatgaat gtaacttaaa actataaact 3050

 tgaagttttt attctatatg ccccttaata gactgtggtt cctgacgcac 3100

 actgttaggt cattattttg ttgtaccaaa gttctagtgg cttcagaaat 3150

 catagcatcc aatgattttt tggtgtctgg ctatgaatac tatggttgag 3200

 aattgtattc agtgattgtt tctgcacact tttcaaataa aaaatgaatt 3250

 tttatcaatt aaaa 3264

<210> 4671
<211> 96
<212> PRT
<213> Homo sapien

<400> 4671
 Met Lys Gln Val Phe Ile Val Leu His Leu Ser Ser Phe Lys Lys
   1               5                  10                  15

 Asp Thr Gln Phe Phe Pro His Cys Ile Leu His Gln Thr Phe Glu
                  20                  25                  30

 Gly Lys Ile Leu Ile Arg Lys Gly Phe Trp Ile Tyr Asn Leu Lys
                  35                  40                  45

 Leu Asn Asn Lys Glu Ile Ile Phe Gln Val Ser Gly Phe Leu Arg
                  50                  55                  60

 Tyr Ile Ile Thr Val Tyr Lys Glu Gly Leu Arg Ala Asp Ile Cys
                  65                  70                  75

 Gln Ser Asp Arg Arg Val Val Phe Ser Ser Leu Leu Pro Ser Phe
                  80                  85                  90

 Lys Thr Leu Lys Glu Val
                  95

<210> 4672
<211> 3895
<212> DNA
<213> Homo sapien

<400> 4672
 caaaacctgg aaaccaaccc caagtgtcct tcatcgggat aatccttaag 50

 gataaacggg tgcgtccaca caggggaata ccactgagca gtgaagagga 100

 gccagttatt gaaacaggta atttggagga accccagaaa cggtacagtg 150

 agtgaaagaa acttgtcttg aaaggttatg tactgtttgg ttccatttgt 200

 atgatattct caaaaagaca caagaccatg gggatggaga ccagatcggt 250

 ggctggagag gctggggtcg gggagggcat gaccaccaga gaaaagggtg 300

 aagagtgttt tgggtggcag agctgtgtgt atgctggctg tggttgtgag 350

 gacaaaatcc acacaagcgc tcaagttcgt aggctgtacg ccagaaaagc 400

 tgtttcacta cataactgaa aaaataagat tgaaaaataa gatgtatata 450

 ttttttgtgt gcgtgtgtag aaaaatactt gaaggtaaac tgcagagtga 500

 taacagtggt ttcttctagg tactgggtta atatgtgatt tttatgtttg 550

 tttgagcttt tctaagtttt ctacattttc cgtacaaaac atgtattact 600

 tctgtaataa aagcagcttg agattattta aggaagcaaa acacttctgt 650

 tgtttctcat caactacagg atgaagtgca ggctccctgg gtggtttgca 700

 ggggccacag gccttggccc cacctcgctg gtgctccctc tactcctttc 750

 tgtgtttgaa gcaagttctg gttcagacag aaagcctggc ctttgagggc 800

 gttgggtccc cacttcctca gtcatagatg tgatgtgctt cccttgactt 850

 gggaccttct gagggatgca aggtggacca aaggacccgt gaatggccag 900

 ggcatgcctg cgtggctttc ggtttcttaa gcagtgattt cagtccactt 950

 aaagggtgtg aaaattctga gaatgctacg gaccaaatat attttatgta 1000

 acagttggga cccggcaaca cttcagggct ctttcaaaat ctggtagcta 1050

 cgagctcttc cgtgactgag atgggacaag agtgaagatt tgtccttgct 1100

 tttagctctg ctccagttca tagttctaat gggaaattat gtgacttaaa 1150

 cccaggctgt gagatgcatc agtgacgtgt gggcataaaa taaaccctcg 1200

 agatgttctc ttgcatggta cactggccta ggcaggaata ttcttgaggc 1250

 taaaactgta gaactgtcag actagtgtta cgaatgtggt ggtgagaggc 1300

 ctgtgcagcc gcggggcctg tgatgtgtct cctgtgtgtc tttcactcct 1350

 atgcagtttg agttcatgat cgagtccatc ctgtatgccc gggatgcctg 1400

 gctgaaggag gacggggtca tttggcccac catggctgcg ttgcaccttg 1450

 tgccctgcag tgctgataag gattatcgta gcaaggtgct cttctgggac 1500

 aacgcgtacg agttcaacct cagcgctctg aagtaagtgt ccacagctgg 1550

 gactggcacc gtcttgtggg gcctcctggt ccacagtctg caggtgggcc 1600

 aaggccctgg gagatcccat acgacggttg gataaatgag ggtacctgtg 1650

 cacccagata ggacaatctg ttgtagcatt ggagtaatta aagcagtatg 1700

 gtgctataac aagacagatg ggcagagcag ggtagaatgc aaggaacaaa 1750

 aattttcgta tgtgaaaaag gtggcattac gattaggagg gagtgagggc 1800

 caagtcagca aattattctg gagcagttga ttagcccttg ttctctcacg 1850

 ccatacgtga aaacttaatt ctgcatggaa tcagcgtcag cgacagacat 1900

 ccatgggggc ctgtgtgcac catcttaggt ggagaaatga gcagcaacaa 1950

 tggatggaat ggaccctggg ctagatagaa tctggcagtc tatgtggcag 2000

 aaatcagcaa aaacacgatt gtaaaagcaa acaagtaatt agagaaatca 2050

 cgtgctgtca ggtcttggaa tcaattagaa agagatgact agccagatgg 2100

 aattgcagcc caatcatgtg aacaggcaaa ccgcaaaaaa taaataaaat 2150

 taccaataaa tacatgaaaa attataatgt tgttagtagt taaaatgcga 2200

 attaaaatac atgctgtttt ccctaccaga caagcaaaga gtaaattaaa 2250

 atagtagccc aggcttgcct ggcagtggca gggaggtgtg gctgccaggg 2300

 ccttagaggt tggcatcagg ctgcccaccc cagtcactgc cagagcctcc 2350

 cacctgagtg ttcctcccgg cactggaagc cagtggccgt ccagaggaac 2400

 gtgattgaat tgctgtatat ccatctggtg gagcactgct gtgtgtctgt 2450

 taaaaaagaa accataggtt tttagggata tgtaatgata tttagaaagg 2500

 gtttaagaga cagtaaagct tggcagaata aaccgtgtat acagaatgga 2550

 tgtttgcttg cataaataaa tttatataaa tatgtctggg ggataaaaat 2600

 aagtatatca caatgctaag acaggcatat ggggaattta agcttttctt 2650

 tatacttgtc catagtttcc aatttttaaa tttgtaattt tttatcagaa 2700

 aaataaatgt gtaaatatag tggaatcttt attaaaacat tcacttttat 2750

 ttgctatttc agaagttact gctttgctta ttttttacaa catttctgtg 2800

 gtaaataatc ggtgacttac aagcctagtg cagccagtga tgggggttgg 2850

 caaacggtga catgcagggg ccatgcggcg tctagtgtct gtttctgtgt 2900

 tgaatttgtg tagcaacaga gcaagtattt ctcctgaaac tcagactcac 2950

 tcaggccacc tcagcccttc tagttccttt cgtttattat agagtaacct 3000

 acagcaggaa taccgcgttc atttactgtt aatagaagat ccacaaaaga 3050

 ttttgaaatc aaatacattc taaaactagg caagacacgc tgcaactccc 3100

 cttgtcctct gggttatgag gggtgagcgt tggtttccgt gtgctcagat 3150

 cccatgaatg agacctcaca gggaagcgcc cagtgactgg caggctcctt 3200

 aatgcctcca ggtcaggctc aggaagtctc tggatgcctg ggtagagtct 3250

 gggtcttctc agagcgggag gcacccaggg cctgtggagg cctgagggct 3300

 gctctggggt tccagggccc cagatagtgg cttagcatcc tggtgacaca 3350

 gaagggagag cactcaccgc ggtcccacgt gtgtgttttg aagcctaaga 3400

 tgtttgcaat gactctcaac agtcgctttg accttttccc ctagatcttt 3450

 agcagttaag gagttttttt caaagcccaa gtataaccac attttgaaac 3500

 cagaagactg tctctctgaa ccgtgcacta tattgcagtt ggacatgaga 3550

 accgtgcaaa tttctgatct agaggtgaga aaaagatgaa ttgctcctta 3600

 cattcgataa tcagtgacca cgaaacactc agaccagagc ctggcttatc 3650

 aaaaaccttc agtgagtgct gggggtgtga gtgaataact aattatttta 3700

 ttatgcaaat aagtgaattt ataaaacgtt tgctactgat tttttccagt 3750

 cttttttctt ttttacgttc tattttgatt ctttcatatt gtacaccatt 3800

 ttatgtctcc agcgtcttca ttttagattt atgtttaata ttctcagcat 3850

 cttcaaaatc aaataaatta tatttcgttt cattatggta aaaaa 3895

<210> 4673
<211> 50
<212> PRT
<213> Homo sapien

<400> 4673
 Lys Pro Gly Asn Gln Pro Gln Val Ser Phe Ile Gly Ile Ile Leu
   1               5                  10                  15

 Lys Asp Lys Arg Val Arg Pro His Arg Gly Ile Pro Leu Ser Ser
                  20                  25                  30

 Glu Glu Glu Pro Val Ile Glu Thr Gly Asn Leu Glu Glu Pro Gln
                  35                  40                  45

 Lys Arg Tyr Ser Glu
                  50

<210> 4674
<211> 1243
<212> DNA
<213> Homo sapien

<400> 4674
 caaggaagtg gagtctagtt ttagggtggg caagtcagca attacaaaag 50

 tgcaattagg tttgagcaga ggaagcatga gagcacctag gaaaggagtc 100

 tttagcattg tcttaaattt cagttatatt aattatacag tacccatctc 150

 ttttccactc ctgaataaca tctaacatct agaaacttta tgaaaatcat 200

 tattgatttg agcattttta acattaactt gttgccttag acaccaactc 250

 tacaacatta cctgtcatat actgaagaat ctcttcttcc agttatgcag 300

 cacctggcta agaatgtagt catggtaaat caaggactta caaagcacat 350

 ggtgagtcaa tatagtggca ttgtaagatg ctgaaaagtg taataattca 400

 aacttaatgc ctgcaaatgc ctggtttatt tttaatgagt taatgtttta 450

 aatgaatacc tgtatcattg catcttgtga ttttttttct tttgcctctt 500

 taattgctat ctttttgtct tccagactgt caagaacaag tatgccacat 550

 cgaagcatgc taagatcagc actctaccac agctgaattc tgcactagtt 600

 caagatttag ccaaggctgt ggcaaaggtg taacttgtaa acttgagttg 650

 gagtactata tttacaaata aaattggcac catgtgccat ctgtacatat 700

 tactgttgca tttactttta ataaagcttg tggccccttt tactttttta 750

 tagcttaact aatttgaatg tggttacttc ctactgtagg gtagcggaaa 800

 agttgtctta aaaggtatgg tggggatatt tttaaaaact ccttttggtt 850

 tacctgggga tccaattgat gtatatgttt atatactggg ttcttgtttt 900

 atatacctgg cttttacttt attaatatga gttactgaag gtgatggagg 950

 tatttgaaaa ttttacttcc ataggacata ctgcatgtaa gccaagtcat 1000

 ggagaatctg ctgcatagct ctattttaaa gtaaaagtct accaccgaat 1050

 ccctagtccc cctgttttct gtttcttctt gtgattgctg ccataattct 1100

 aagttattta cttttaccac tatttaagtt atcaacttta gctagtatct 1150

 tcaaactttc actttgaaaa atgagaattt tatattctaa gccagttttc 1200

 attttggttt tgtgttttgg ttaataaaac aatactcaaa tac 1243

<210> 4675
<211> 57
<212> PRT
<213> Homo sapien

<400> 4675
 Lys Glu Val Glu Ser Ser Phe Arg Val Gly Lys Ser Ala Ile Thr
   1               5                  10                  15

 Lys Val Gln Leu Gly Leu Ser Arg Gly Ser Met Arg Ala Pro Arg
                  20                  25                  30

 Lys Gly Val Phe Ser Ile Val Leu Asn Phe Ser Tyr Ile Asn Tyr
                  35                  40                  45

 Thr Val Pro Ile Ser Phe Pro Leu Leu Asn Asn Ile
                  50                  55

<210> 4676
<211> 2533
<212> DNA
<213> Homo sapien

<400> 4676
 cgcagccctg gcgcagacgc gtgggctccg tggcgatgcg gggtgttgcc 50

 tgaggctcca ctgaagctat ggcataattt gcagaatttg cacttcatta 100

 cttttctgaa attcaaacaa attctgaaac tgcacgagtt ctggctgaga 150

 gctgtggatc tgtgcatttt gatggtgaca gtgcctacgt ggggatgagt 200

 gacggaaacc cagagctcct gtcaaccagc cagacctaca acggccagag 250

 cgagaacaac gaagactatg agatcccccc gataacacct cccaacctcc 300

 cggagccatc cctcctgcac ctgggggacc acgaagccag ctaccactcg 350

 ctgtgccacg gcctcacccc caacggtctg ctccctgcct actcctatca 400

 ggccatggac ctcccagcca tcatggtgtc caacatgcta gcacaggaca 450

 gccacctgct gtcgggccag ctgcccacga tccaggagat ggtccactcg 500

 gaagtggctg cctatgactc gggccggccc gggcccctgc tgggtcgccc 550

 ggcaatgctg gccagccaca tgagtgccct cagccagtcc cagctcatct 600

 cgcagatggg catccggagc agcatcgccc acagctcccc atcaccgccg 650

 gggagcaagt cagcgacccc ctctccctcc agctccactc aggaagagga 700

 gtcggaagtg catttcaaga tctcgggaga aaagagacct tcagccgacc 750

 caggaaaaaa ggccaagaac ccgaagaaga agaaaaagaa ggaccccaat 800

 gagccgcaga agcctgtgtc ggcctacgca ctcttcttca gagacactca 850

 ggccgccatc aagggtcaga accccagtgc cactttcggt gacgtgtcca 900

 aaatcgtggc ctccatgtgg gacagcctgg gagaggaaca gaagcaggcc 950

 tacaagagga agacagaagc agcaaagaag gaatatctga aggccctggc 1000

 agcctaccgg gctagcctcg tctccaagag ctccccagat caaggtgaga 1050

 ccaagagcac tcaggcaaac ccaccagcca aaatgctccc acccaagcag 1100

 cccatgtatg ccatgccagg cctggcctcc ttcctgacgc cgtcggacct 1150

 gcaggccttc cgcagtgggg cctcccctgc cagcctcgcc cggacgctgg 1200

 gctccaagtc tctgctgcca ggcctcagtg cgtccccgcc gccgccaccc 1250

 tccttcccgc tcagccccac actgcaccag cagctgtcac tgccccctca 1300

 cgcccagggc gccctcctca gtccacctgt tagcatgtcc ccagcccccc 1350

 agccccctgt cctgcccacc cccatggcac tccaggtgca gctggcgatg 1400

 agcccctcac ctccagggcc acaggacttc ccgcacatct ctgagttccc 1450

 cagcagctcg ggatcctgct cacctggccc atccaacccc accagcagcg 1500

 gggactggga cagcagctac cccagtgggg agtgtggcat cagcacctgc 1550

 agcctgctcc ccagggacaa atcgctctac ctcacctaat cccgcctccc 1600

 taccatccct gaggctcgct ggaaggcact gctcagagcc tgaagggctg 1650

 acagcagaaa agaggccctg gccagaggca gggtggccca tcggagagag 1700

 cagtgacaca cccattgccc gggggctgag tctcttcctc aacctcccac 1750

 cagactctgc agaggcagcc cactgcccac caccagccca aagaacctgc 1800

 aggaaccttc cgcccgctga cctgcttgct ccagggtaac tgtggaccct 1850

 gtcctcgccc tgcgcacggt accctatgtc tggacacccg gccccagctc 1900

 cagccccagc ccaggtgggc cgcccctggc ggggtcgctt accaacggac 1950

 acccacccca gatgcatggg ccagagggcc ggcccccggc atagatgtgc 2000

 acatcggttt tccagtgtga acaaaagatt acgaaaccta gaaactgttg 2050

 gttccgtgta agtagttgac tacgtgtttt agaactgtgc tgaagacatc 2100

 tgtaagacta ttttgtgggg gaaaaaagta gtttccttta aggtaaaaag 2150

 cattttatat gatccttagc acatttttaa gttttatctt aagggagacg 2200

 cgcacaaaag cggctgccaa accgtttcgt catcctcaca gcaaggaccg 2250

 gacgcttgct agccaccccg gagcactgct ctccttttaa tcatgtattc 2300

 atctatttta aattgccggc gacgactttt gtctatttat gaagaaacct 2350

 tgagaacgaa gttacagctt atcctaccgt gtgtgtggtt ttggggtttc 2400

 gtttgggttt gggttcttga cgtcgtttgc agctgtttcc tggccctggc 2450

 gagtgtctgt cttggtgccc agtgcttctc tcaaatctct ttataataaa 2500

 acttctgaaa agctgaaaaa aaaaaaaaaa aaa 2533

<210> 4677
<211> 464
<212> PRT
<213> Homo sapien

<400> 4677
 Met Ser Asp Gly Asn Pro Glu Leu Leu Ser Thr Ser Gln Thr Tyr
   1               5                  10                  15

 Asn Gly Gln Ser Glu Asn Asn Glu Asp Tyr Glu Ile Pro Pro Ile
                  20                  25                  30

 Thr Pro Pro Asn Leu Pro Glu Pro Ser Leu Leu His Leu Gly Asp
                  35                  40                  45

 His Glu Ala Ser Tyr His Ser Leu Cys His Gly Leu Thr Pro Asn
                  50                  55                  60

 Gly Leu Leu Pro Ala Tyr Ser Tyr Gln Ala Met Asp Leu Pro Ala
                  65                  70                  75

 Ile Met Val Ser Asn Met Leu Ala Gln Asp Ser His Leu Leu Ser
                  80                  85                  90

 Gly Gln Leu Pro Thr Ile Gln Glu Met Val His Ser Glu Val Ala
                  95                 100                 105

 Ala Tyr Asp Ser Gly Arg Pro Gly Pro Leu Leu Gly Arg Pro Ala
                 110                 115                 120

 Met Leu Ala Ser His Met Ser Ala Leu Ser Gln Ser Gln Leu Ile
                 125                 130                 135

 Ser Gln Met Gly Ile Arg Ser Ser Ile Ala His Ser Ser Pro Ser
                 140                 145                 150

 Pro Pro Gly Ser Lys Ser Ala Thr Pro Ser Pro Ser Ser Ser Thr
                 155                 160                 165

 Gln Glu Glu Glu Ser Glu Val His Phe Lys Ile Ser Gly Glu Lys
                 170                 175                 180

 Arg Pro Ser Ala Asp Pro Gly Lys Lys Ala Lys Asn Pro Lys Lys
                 185                 190                 195

 Lys Lys Lys Lys Asp Pro Asn Glu Pro Gln Lys Pro Val Ser Ala
                 200                 205                 210

 Tyr Ala Leu Phe Phe Arg Asp Thr Gln Ala Ala Ile Lys Gly Gln
                 215                 220                 225

 Asn Pro Ser Ala Thr Phe Gly Asp Val Ser Lys Ile Val Ala Ser
                 230                 235                 240

 Met Trp Asp Ser Leu Gly Glu Glu Gln Lys Gln Ala Tyr Lys Arg
                 245                 250                 255

 Lys Thr Glu Ala Ala Lys Lys Glu Tyr Leu Lys Ala Leu Ala Ala
                 260                 265                 270

 Tyr Arg Ala Ser Leu Val Ser Lys Ser Ser Pro Asp Gln Gly Glu
                 275                 280                 285

 Thr Lys Ser Thr Gln Ala Asn Pro Pro Ala Lys Met Leu Pro Pro
                 290                 295                 300

 Lys Gln Pro Met Tyr Ala Met Pro Gly Leu Ala Ser Phe Leu Thr
                 305                 310                 315

 Pro Ser Asp Leu Gln Ala Phe Arg Ser Gly Ala Ser Pro Ala Ser
                 320                 325                 330

 Leu Ala Arg Thr Leu Gly Ser Lys Ser Leu Leu Pro Gly Leu Ser
                 335                 340                 345

 Ala Ser Pro Pro Pro Pro Pro Ser Phe Pro Leu Ser Pro Thr Leu
                 350                 355                 360

 His Gln Gln Leu Ser Leu Pro Pro His Ala Gln Gly Ala Leu Leu
                 365                 370                 375

 Ser Pro Pro Val Ser Met Ser Pro Ala Pro Gln Pro Pro Val Leu
                 380                 385                 390

 Pro Thr Pro Met Ala Leu Gln Val Gln Leu Ala Met Ser Pro Ser
                 395                 400                 405

 Pro Pro Gly Pro Gln Asp Phe Pro His Ile Ser Glu Phe Pro Ser
                 410                 415                 420

 Ser Ser Gly Ser Cys Ser Pro Gly Pro Ser Asn Pro Thr Ser Ser
                 425                 430                 435

 Gly Asp Trp Asp Ser Ser Tyr Pro Ser Gly Glu Cys Gly Ile Ser
                 440                 445                 450

 Thr Cys Ser Leu Leu Pro Arg Asp Lys Ser Leu Tyr Leu Thr
                 455                 460

<210> 4678
<211> 2101
<212> DNA
<213> Homo sapien

<400> 4678
 ggagggtttt gctctttgtg tgggtgtgtg agtggctatg atcctagttg 50

 tccagctgct gcgtggagaa taagtaaagc aggtctgaat gacaccaggt 100

 cgctgctgtc ttgcggctga cattcaggta gagacgttca tcttcactga 150

 cggggaagat gaggccctgg ccaggcacac gggcaacgtg gtcatcacaa 200

 actgctcggc cgcccacagc cgccaggcgc tgtcctgcaa gatggccgtg 250

 gagtatgacc gcttcatcga gtccggcagg aagtggttct gccacgtgga 300

 cgatgacaac tacgtcaacc tgcgggccct gctgcggctg ctggccagct 350

 acccgcacac gcgggacgtc tacgtcggca agcccagcct ggacaggccc 400

 atccaggcca tggagcgggt cagcgagaac aaggtgcgtc ctgtccactt 450

 ctggtttgcc acgggcggcg ctggcttctg catcagccgt gggctggctc 500

 tgaagatgag cccgtgggcc agcgggggtc acttcatgaa tacggctgag 550

 cggatccggc tgcctgatga ctgcaccatc ggctacatcg tggaggccct 600

 gctgggtgtg cccctcatcc gcagcggcct cttccactcc cacctggaga 650

 acctgcagca ggtgcccacc tcggagctcc acgagcaggt gacgctgagc 700

 tacggtatgt ttgaaaacaa gcggaacgcc gtccacgtga aggggccctt 750

 ctcggtggag gccgacccat ccaggttccg ctccatccac tgccacctgt 800

 acccggacac accctggtgt ccccgcactg ccatcttcta gtggccatgg 850

 ctgagaccca atccctgggc gcccctggta tccaaagggc ccagggaccc 900

 tgttgcgctg ccctggcctc ggcattcgag gctcccctag ggccgtgcct 950

 gtgcgtgtgc gtgtgcatgt gcgtgtgtgt gtgtgtgtac tgcatgccca 1000

 cccgggtagc aggctgctgg gcagttctgc tctgtggagg ggcgggcacc 1050

 agcgccactt atgtgcctct gctccgaggg ccagtgggct gcagggcctg 1100

 cttggaggaa ggatttgtgt gtcggaggcc actccgaggg caattctgtt 1150

 aggatttttg gatctttcta cagctacggg gctccgggct actttgcagg 1200

 gatgcgatgc gtaggtgcct ttctcttcct gctgaccaca agctctgtgc 1250

 tgggggtacc tgtgccctga agtcctggcc cctgtgtcat agccccaagt 1300

 acgactcact gagccatgct cattgcaggg gaggctgggt ctgggggtgc 1350

 gtgacccaat ccccttcctc ctggcctgga cgctgtggct taagagtaac 1400

 agcagccacc gcccagttcc agtggcccca cgaagccccc agtggctggc 1450

 tgtccagctg ggcaaacagt ggcacccctc ccagctcttc tgagtgggga 1500

 gtcttccagg cctcctcaga ggtcttccct ttgcctcccc aggacagggt 1550

 gagtcagagc tcagcattta atctcctctc caaagtagag agcaagtcgc 1600

 ccacagtggg cgtgtctgta aatattgtga cagtattttt ttactgtgct 1650

 gttttttttg aaaggggatg ggtaaaaagt agggtgttct tgttttttgc 1700

 ttgggagggt gggggtgggg gagggtctta ttttatctta tcttttctgt 1750

 ggatcagaaa aaacagaagc caaactcggg gtcatctttg tttttaaagc 1800

 tgaagtggga ctgtctggca ctctgtgtat ttatgcgttc cagcatctgg 1850

 aacctcccat ccctgccctc ctcctgtgta gctgccacct ccccgctggg 1900

 cccagcatgg ctcacctgtc ccgtgggctg tgtttcttgt tgtttttctc 1950

 tttgcaaaga catagctagg aaagcgaatg ataagggaaa agttctcagg 2000

 gaattgaagt gttgttgcta tggtgacgtc cttttgctgt gaataaaggt 2050

 gctctttgca gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2100

 a 2101

<210> 4679
<211> 250
<212> PRT
<213> Homo sapien

<400> 4679
 Met Thr Pro Gly Arg Cys Cys Leu Ala Ala Asp Ile Gln Val Glu
   1               5                  10                  15

 Thr Phe Ile Phe Thr Asp Gly Glu Asp Glu Ala Leu Ala Arg His
                  20                  25                  30

 Thr Gly Asn Val Val Ile Thr Asn Cys Ser Ala Ala His Ser Arg
                  35                  40                  45

 Gln Ala Leu Ser Cys Lys Met Ala Val Glu Tyr Asp Arg Phe Ile
                  50                  55                  60

 Glu Ser Gly Arg Lys Trp Phe Cys His Val Asp Asp Asp Asn Tyr
                  65                  70                  75

 Val Asn Leu Arg Ala Leu Leu Arg Leu Leu Ala Ser Tyr Pro His
                  80                  85                  90

 Thr Arg Asp Val Tyr Val Gly Lys Pro Ser Leu Asp Arg Pro Ile
                  95                 100                 105

 Gln Ala Met Glu Arg Val Ser Glu Asn Lys Val Arg Pro Val His
                 110                 115                 120

 Phe Trp Phe Ala Thr Gly Gly Ala Gly Phe Cys Ile Ser Arg Gly
                 125                 130                 135

 Leu Ala Leu Lys Met Ser Pro Trp Ala Ser Gly Gly His Phe Met
                 140                 145                 150

 Asn Thr Ala Glu Arg Ile Arg Leu Pro Asp Asp Cys Thr Ile Gly
                 155                 160                 165

 Tyr Ile Val Glu Ala Leu Leu Gly Val Pro Leu Ile Arg Ser Gly
                 170                 175                 180

 Leu Phe His Ser His Leu Glu Asn Leu Gln Gln Val Pro Thr Ser
                 185                 190                 195

 Glu Leu His Glu Gln Val Thr Leu Ser Tyr Gly Met Phe Glu Asn
                 200                 205                 210

 Lys Arg Asn Ala Val His Val Lys Gly Pro Phe Ser Val Glu Ala
                 215                 220                 225

 Asp Pro Ser Arg Phe Arg Ser Ile His Cys His Leu Tyr Pro Asp
                 230                 235                 240

 Thr Pro Trp Cys Pro Arg Thr Ala Ile Phe
                 245                 250

<210> 4680
<211> 2191
<212> DNA
<213> Homo sapien

<400> 4680
 gggcgttgct gacagtgtgg agagcagtgg ctgggggaag gggcttagtg 50

 aagtgtgcac ccagaggggt ggagaggaga tgtctgactg agggccatct 100

 gaggtcacgg tgcatcctga ggacagagct gagattggat atcaacgatg 150

 tgggctcagc agccctggag taggagctgg gaaggtcagt gccttggtgg 200

 cggcagggcc agggcactga gagtattggc agggcacagc aggggaaagg 250

 gaagagaagc agagggtggg actctccctc tgtgctggaa gagggctaac 300

 accagcccgg actctccact ctggctaggc caagggggcc ctctgtcctc 350

 tgtgttgccc tagggctcgg tgacctctgt catagcactg accacatggt 400

 atcctgcctg tgccttcctc tagctgtccc cgccctactc cggaccgccc 450

 caaagactcc atgggatgga cctgagtcag ccgaatccca gccccttccc 500

 ttgggcctgc tgtggtgctg gacatcagtg acagacggaa gcaggagacc 550

 atcaaggcta cgggaggccc ggggcgcttg cgaagatgaa gtttggctgc 600

 ctctccttcc ggcagcctta tgctggcttt gtcttaaatg gaatcaagac 650

 tgtggagacg cgctggcgtc ccctgctgag cagccagcgg aactgtacca 700

 tcgccgtcca cattgctcac agggactggg aaggcgatgc ctggcgggag 750

 ctgctggtgg agagactcgg gatgactcct gctcagattc aggccttgct 800

 ccaggaaacg gggaaaagtt tggtcgagga gtgatagcgg gactcgttga 850

 cattggggaa actttgcaat gccccgaagg acttaactcc cgatgaggtt 900

 gtggaactag aaaatcaagc tgcactgacc aacctgaagc agaagtacct 950

 gactgtgatt tcaaacccca ggtggttact ggagcccata cctaggaaag 1000

 gaggcaagga tgtattccag aatccataga ggttcagctg gcgaatgaaa 1050

 ctcgtcaagt tgtctgtttt gaagatcctc tctgcacctt tccgttgaag 1100

 aacctccctc tggaagagat ccttgtcgat gatcacggcg tctccatcat 1150

 cgttccagct cacagacttg aatgtgtctt cctccacaat cgtccaaagc 1200

 tttcttggga aggagagcct aaaaaggttg tggttgtctt ccacgttgac 1250

 cacgcgttgg tttcggtctt ctggtggtga gttatcttgg gagcctggat 1300

 cttggctcat ggcttggtcc tcgtgcctgt ccaaaacctc gctggaatct 1350

 ggatttggat caggtgaaga accagatggg cccccgcttg ttggctctcc 1400

 accaacagat ggggccagct tggcttcata ttcctgttca gtgttctgac 1450

 tcgccatgga gctacaccag aatcaggagc attttgtacc caaggccctt 1500

 atcactgtcc tagcaagtcc aaaatgcctt cagtcagagt aggcgtgccc 1550

 aataaatact gtccacaaaa ttctagagtc tcggtatcag ggcaaccagt 1600

 ggcttaactc atcatctgct gtatttgtcg catgatgtca caaaggtggc 1650

 tctcagccaa tctggagagg gggccctggc caggtgttgg gggagtagac 1700

 aggtggcatg gccttcagct tctccctctt ctaaaagtat aaacaggcat 1750

 ggttcaagtt cccagaaaag tctcccatct tctgacagtc acattgtgtc 1800

 aaagggccag gccccagatg agctgagaaa ccatggctct atggccactc 1850

 ccaaccctga agacagggga ggccatttgc tggcctctaa tttgctcaag 1900

 agccagcccc tagttatccc tagcttgggt ttcaccaaga ctgcctgact 1950

 cagatggacc cctcatgggt gactgccttc taggagatgg tggtccctac 2000

 caggctgttt ggcctgatct gtgtggtagc acccctcttt tccaatcccc 2050

 ccatctcctt tctgctttgg tctcttccag gtactcctaa tgattggttg 2100

 catgtgctcc agtgggccca gataaagtgt ttcttattcc ccttggtcaa 2150

 gttgtcccca gagtggtgct gtgcctgagc atggtgggag c 2191

<210> 4681
<211> 56
<212> PRT
<213> Homo sapien

<400> 4681
 Ala Leu Leu Thr Val Trp Arg Ala Val Ala Gly Gly Arg Gly Leu
   1               5                  10                  15

 Val Lys Cys Ala Pro Arg Gly Val Glu Arg Arg Cys Leu Thr Glu
                  20                  25                  30

 Gly His Leu Arg Ser Arg Cys Ile Leu Arg Thr Glu Leu Arg Leu
                  35                  40                  45

 Asp Ile Asn Asp Val Gly Ser Ala Ala Leu Glu
                  50                  55

<210> 4682
<211> 1249
<212> DNA
<213> Homo sapien

<400> 4682
 cttctcatta gcattaacta gttatgccca gcttgggaga gccttctttg 50

 ggcttatcat ttattataag cccagaaata ggtgactaat cagagataaa 100

 tgtatgggtt gtctgtatct agttttatgc cttttttttt gcctaagacg 150

 tagtcaaatt aatattttaa ctaatacatc ttagcagagt ttagttaagc 200

 acaaagttaa cagtgggtag gattgaatct tgaaagtaat catgtctgta 250

 atgtttttca tgcatgcaaa aagcacagac aaaaccactc atgccctatt 300

 aataaacaaa atacagatca aagttttcaa aagtaatcac tctatttatt 350

 ctaaatgtct gtggctttag gaaaatacca ccagctagta cttacctatt 400

 taaagatgta gaatttatta tcctctaata ttcttatcag ttgtttccac 450

 aactttagtt tactattgga ctttcaaaaa tttaaagaat tacaagtaaa 500

 attcattaaa cacttgtgtg tgaatagtaa tacacagtaa ttagtacagc 550

 atgttgcttc ttcaacaaat tgagttttca gggaaatcag caagtaaatg 600

 aaatataaat ttttggtaaa agtatcaaac attcatcttg cccatttttc 650

 ctcttaaact ttattatcta atcaaacata gttttccata agatgtaata 700

 aaatatagat aaggttggaa tatttgagga tccatttgtg gaactgaatt 750

 taatgagact tcattggtga tacactcaat ttttactggg taattagcta 800

 ataatgttgg tcactgtctc acagttcaag tagctttaag atgatgtggc 850

 aaggaaaaca caaagctttt gggtaaccag cgttcttaaa tgtatggttt 900

 ttgaccaggt gaacccttta gaagtgattt ctgttttaaa agtatgtact 950

 taaaatacct ttggctgtga tgaatgtaga tcccagcaga ataccaaaat 1000

 cctatttttt ttgactgagt atttgtagat gcttaatgac tgaaatgaat 1050

 ttggaggcac tgatgaaagt gattttttta aagttctcag gtactgttca 1100

 attatttaat gttaagttta gtatcaagat acagttgttt ttaaaatgcc 1150

 aaaatgctgt ttattataca gaatatttta ttacatttgc aatatctttg 1200

 tatatagtga tttttttctt gataataaat ggaaaaattc taaaacaaa 1249

<210> 4683
<211> 2938
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1299-1507, 2016-2062
<223> Unknown base

<400> 4683
 cgggcgatca gaagcaggtc acacagcctg tttcctgttt tcaaacgggg 50

 aacttagaaa gtggcagccc ctcggcttgt tgccggagct gagaaccaag 100

 agctcgaagg ggccatatga cactcctccc ggacccctgg acacacacag 150

 ccctggagac tggagccttg gagcatggca agtccagagc accctgggag 200

 ccctggctgc atgggaccca taacccagtg cacggcaagg acccagcagg 250

 aagcaccagc cactggcccc gacctcccgc acccaggacc tgacgggcac 300

 ttagacacac acagtggcct gagctccaac tccagcatga ccacgcggga 350

 gcttcagcag tactggcaga accagaaatg ccgctggaag cacgtcaaac 400

 tgctctttga gatcgcttca gctcgcatcg aggagagaaa agtctctaag 450

 tttgtggtgt accaaatcat cgtcatccag actgggagct ttgacaacaa 500

 caaggccgtc ctggaacggc gctattccga cttcgcgaag ctccagaaag 550

 cgctgctgaa gacgttcagg gaggagatcg aagacgtgga gtttcccagg 600

 aagcacctga ctgggaactt cgctgaggag atgatctgtg agcgtcggcg 650

 cgccctgcag gagtacctgg gcctgctcta cgccatccgc tgcgtgcgcc 700

 gctcccggga gttcctggac ttcctcacgc ggccggagct gcgcgaggct 750

 ttcggctgcc tgcgggccgg ccagtacccg cgcgccctgg agctgctgct 800

 gcgcgtgctg ccgctgcagg agaagctcac cgcccactgc cctgcggccg 850

 ccgtcccggc cctgtgcgcc gtgctgctgt gccaccgcga cctcgaccgc 900

 cccgccgagg ccttcgcggc cggagagagg gccctgcagc gcctgcaggc 950

 ccgggagggc catcgctact atgcgcctct gctggacgcc atggtccgcc 1000

 tggcctacgc gctgggcaag gacttcgtga ctctgcagga gaggctggag 1050

 gagagccagc tccggaggcc cacgccccga ggcatcaccc tgaaggagct 1100

 cactgtgcga gaatacctgc actgagccgg cctgggaccc cgcagggacg 1150

 ctggagattt ggggtcacca tggctcacag tgggctgttt ggggttcttt 1200

 tttttatatt tattccttat actattattc agttattctg gaggacagtc 1250

 ttgcatctgt cacaccatga ctgaagtgca ggtggcgtca cattatgtnn 1300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1500

 nnnnnnncac acagtgtgag ccaccacccc tggcctgggg ttcattttta 1550

 atgggaaaag ccactggggg ctctaactcg ctgggtgact ttggacaagc 1600

 ccctcctctg gtcctcaatt tctccatctg tattggacag aggtgctcct 1650

 gggacccctt ggaagcctct gcttgtgtcc cacgtcctct tgatgccagg 1700

 gccacttcat ctccaaaaca caaaaccaac tgccaaaacc gtccagagca 1750

 gtgtccaccc caccagtgtc tttgtgggaa gctggagaag aagtttacct 1800

 cacacattct agacaaaact tagtccattt ccttgaagac agttctctcc 1850

 agctgctcca aggcttttct ctctgttcct tccaccttgg aattgcttta 1900

 aaatatttcc atccattatc ctaatactat cttagtattc tagcccttcc 1950

 cccttaccat gtagacctga caaagcaaaa caaaagctca cctattgccc 2000

 tcaagaacag cctctnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2050

 nnnnnnnnnn nncacggtgg gagttgtatg ccatcctttt gaagggtggg 2100

 aggaccctgg accagaaagc aataatggca taagattctg tgataccagg 2150

 catttttggc aagggaagtt gccaacaatt tttctggctg ggatggcata 2200

 gcacattgtc taggggtgga ttttcattca taaggcagct gttccctgaa 2250

 tggcttccct gggttatgta gaaacagcct ggggaggagg tgatacaaca 2300

 tacttaatgg ggcctctggg cagaaaacag actgaatcct caacactgcc 2350

 ccttttgagg gtctgtgatc ctggaacttc tctgatggac tgggatgccc 2400

 ttaactgagg tctgctgtct ggaaaggaca ccacaggccc agaatgaagg 2450

 ggcatctgga ccaatgacct agattcaaca cagggcttgg agctggtggt 2500

 acaggctggt tttggcccaa tgtgtgttgg aggctggaag cccctgaaga 2550

 cctaaactgc ctggatgagc ttattagggt gaattaatga gtctgtaatt 2600

 tgggaacctt aatgtgagac accacttaag gagaggaact tggcccagca 2650

 agtgatcact ctagaagtgg acagctatgc actagactgc accagaatct 2700

 gttcaacagc gacaccttgt ggtaaaaact gtagacgccc catcaggctg 2750

 gatgggaaac tagaaacaga ctgtctcatc tttggacaga tatccctcaa 2800

 atctcccaat ctactccagg gaaaagacac ttcaagtgag agatattgga 2850

 cttcttgaaa atctaggcct atggaaaatt aaagtgttaa atggaaaaat 2900

 taaagagcta tgagtctatt tgtaatgatg aaacagaa 2938

<210> 4684
<211> 316
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1299-1507, 2016-2062
<223> Unknown amino acid

<400> 4684
 Met Ala Ser Pro Glu His Pro Gly Ser Pro Gly Cys Met Gly Pro
   1               5                  10                  15

 Ile Thr Gln Cys Thr Ala Arg Thr Gln Gln Glu Ala Pro Ala Thr
                  20                  25                  30

 Gly Pro Asp Leu Pro His Pro Gly Pro Asp Gly His Leu Asp Thr
                  35                  40                  45

 His Ser Gly Leu Ser Ser Asn Ser Ser Met Thr Thr Arg Glu Leu
                  50                  55                  60

 Gln Gln Tyr Trp Gln Asn Gln Lys Cys Arg Trp Lys His Val Lys
                  65                  70                  75

 Leu Leu Phe Glu Ile Ala Ser Ala Arg Ile Glu Glu Arg Lys Val
                  80                  85                  90

 Ser Lys Phe Val Val Tyr Gln Ile Ile Val Ile Gln Thr Gly Ser
                  95                 100                 105

 Phe Asp Asn Asn Lys Ala Val Leu Glu Arg Arg Tyr Ser Asp Phe
                 110                 115                 120

 Ala Lys Leu Gln Lys Ala Leu Leu Lys Thr Phe Arg Glu Glu Ile
                 125                 130                 135

 Glu Asp Val Glu Phe Pro Arg Lys His Leu Thr Gly Asn Phe Ala
                 140                 145                 150

 Glu Glu Met Ile Cys Glu Arg Arg Arg Ala Leu Gln Glu Tyr Leu
                 155                 160                 165

 Gly Leu Leu Tyr Ala Ile Arg Cys Val Arg Arg Ser Arg Glu Phe
                 170                 175                 180

 Leu Asp Phe Leu Thr Arg Pro Glu Leu Arg Glu Ala Phe Gly Cys
                 185                 190                 195

 Leu Arg Ala Gly Gln Tyr Pro Arg Ala Leu Glu Leu Leu Leu Arg
                 200                 205                 210

 Val Leu Pro Leu Gln Glu Lys Leu Thr Ala His Cys Pro Ala Ala
                 215                 220                 225

 Ala Val Pro Ala Leu Cys Ala Val Leu Leu Cys His Arg Asp Leu
                 230                 235                 240

 Asp Arg Pro Ala Glu Ala Phe Ala Ala Gly Glu Arg Ala Leu Gln
                 245                 250                 255

 Arg Leu Gln Ala Arg Glu Gly His Arg Tyr Tyr Ala Pro Leu Leu
                 260                 265                 270

 Asp Ala Met Val Arg Leu Ala Tyr Ala Leu Gly Lys Asp Phe Val
                 275                 280                 285

 Thr Leu Gln Glu Arg Leu Glu Glu Ser Gln Leu Arg Arg Pro Thr
                 290                 295                 300

 Pro Arg Gly Ile Thr Leu Lys Glu Leu Thr Val Arg Glu Tyr Leu
                 305                 310                 315

 His


<210> 4685
<211> 935
<212> DNA
<213> Homo sapien

<400> 4685
 gcaggttccg ggaggtcagg ttgtattcct ggcgggtcgt ctggctgggt 50

 gggccccgga ggtcgtggct cgggagcagg gaggcgtagg ggggccggcc 100

 tgctgtgatg acattccaat taaagcacgt gttagactgc tgacgcgggt 150

 gatgcgaact ggagtctgag cctgcccgag cggagctggg agggggctgg 200

 cgggcgggcg cgcgcacacc cgctgatcta tcactctcgt tcttgtagct 250

 cccagccgag gacgtcggat gtcatcgtcc ttgctgcttt gccaccccat 300

 tcccgtcaat aaagtggttt gaacccaacc ctggtgtcgg tgtgtgtcgt 350

 tggcgacgcg ctgtctttga gcccccgccg agcttcctcg tggcgccggg 400

 ggtcaatctg cagcgctaga gcatgtgctt gcgcataact ggggccgcct 450

 ggcctcccgc gggcggcctt tttaaccgcg agcgacaaga agtaacctga 500

 ctgtccggct gctaggctgg gcaattttcc agctgttttg ccacgacagg 550

 cctcaatccg taataccaag gctggaatgg cgtgttaggg gggcggtggc 600

 tgacggggat acgcggactc ttgatgcgta aggagtgccc ctctgctccc 650

 atacgttccc cagcccagcc ttccctgagt gtatcgcgcg cgctgtgcct 700

 tcgccgtgag ttcgacataa gtcccaggct gtcgcgtctg ccatcagacg 750

 cgcagattta gttgaaggca gcgtggaatg gcgtctgcag ggctgttgtg 800

 tacttgacat aaacagattc ggtgtggaac tgcattgagt taactcctga 850

 ctaaagggta atcgacctgt ttacaaataa ccatgcagga gtactgacaa 900

 gcatgggact aaagcgttgg gcaggttcat ctgtc 935

<210> 4686
<211> 55
<212> PRT
<213> Homo sapien

<400> 4686
 Gln Val Pro Gly Gly Gln Val Val Phe Leu Ala Gly Arg Leu Ala
   1               5                  10                  15

 Gly Trp Ala Pro Glu Val Val Ala Arg Glu Gln Gly Gly Val Gly
                  20                  25                  30

 Gly Pro Ala Cys Cys Asp Asp Ile Pro Ile Lys Ala Arg Val Arg
                  35                  40                  45

 Leu Leu Thr Arg Val Met Arg Thr Gly Val
                  50                  55

<210> 4687
<211> 901
<212> DNA
<213> Homo sapien

<400> 4687
 cttgggggca tggcacagag ctggtcctgt attctccagg gtccggagct 50

 ggccagggga gggaagggcg ttagataagg cactctgggc tgtcaggaga 100

 ctgcctactg ggtgggtcaa cttatttccc actatgacat ttatatcttt 150

 atttttcaca attatattga aggcagtggg agaggggaga gggtgggttt 200

 tacctgatat taaggggtgg caccccttcc ccaggcctga tgcaggtcca 250

 tctagacagc tcagattagc ctaggccatg ccctagggac acggcctagg 300

 ggagctgggc tggagggggt ctgcctgggt aaggggatct ggcttggccc 350

 tgagctgctt agggacaggt gagtccttgg gggcatggca cagagctggt 400

 cctgtattct ccagggtccg gagctggcca ggggcgggga ggaggaggat 450

 ggcttctcct gggagaaggt gggctggcct ttcttggcaa gcggtcctct 500

 ggcccctggg gagtggggtg ggtgaggctg tgccttgtag ggggagaggg 550

 gagggggctt tgtgtgcacc attctgtaaa acacactcaa gattctaaga 600

 ctattaaaga ggatttataa cagtctagtc tggaatggta gggatgctgc 650

 ttcctggggc aggggaggac ccagggcaga gggtgtgagc agagtggctg 700

 ggtctgctgg agactgctgg acccctcact gctctgccct ccccgcaggc 750

 atctgcttct gcagcctgaa ccttaggacc gtgatgggcc aggctctgat 800

 gggcctgcct gcatgccggg gtgcctggag tttgatttgg tgctaagaga 850

 ggtatagatt gtacctctca attcctgctt ctgaaacgtg gggtaggagg 900

 t 901

<210> 4688
<211> 90
<212> PRT
<213> Homo sapien

<400> 4688
 Leu Gly Ala Trp His Arg Ala Gly Pro Val Phe Ser Arg Val Arg
   1               5                  10                  15

 Ser Trp Pro Gly Glu Gly Arg Ala Leu Asp Lys Ala Leu Trp Ala
                  20                  25                  30

 Val Arg Arg Leu Pro Thr Gly Trp Val Asn Leu Phe Pro Thr Met
                  35                  40                  45

 Thr Phe Ile Ser Leu Phe Phe Thr Ile Ile Leu Lys Ala Val Gly
                  50                  55                  60

 Glu Gly Arg Gly Trp Val Leu Pro Asp Ile Lys Gly Trp His Pro
                  65                  70                  75

 Phe Pro Arg Pro Asp Ala Gly Pro Ser Arg Gln Leu Arg Leu Ala
                  80                  85                  90

<210> 4689
<211> 1110
<212> DNA
<213> Homo sapien

<400> 4689
 attttatagt cttcggggaa aaccggctgt ggagaaggaa atagggcccg 50

 gcgctgagtg agcgtggttg cgtgtccttt gcagacactt tctggggcga 100

 ggtgacatgg cgagagtctt ggatcggtgg acgtagacgg tagacagttc 150

 gcgtgcgttt ccttcgccta cttggcctac atgccttctg cccgtgaagc 200

 gatgtttccc ctcgaaaggc cgtaggctac gccgtcagaa tcggtttttc 250

 agtgagtttt gacccctccg acgctccgtc gcctgacaga atcgcggcgt 300

 tcttcgtacc cgcccatcct ccgcggacgc ccgctgccat ggcgactctg 350

 ctgcgccctg tcctccgtcg gctctgcggg ctcccgggcc tacagcggcc 400

 tgcggcaggc aagtggcgcc gggttctggg cgcaggcggg aaggagcctg 450

 agggcgcccg gctcctctga cctcggcctt tttcttgccc cgcagaaatg 500

 cccctccggg ctaggagcga cggcgccggc ccgctatact cgcaccacct 550

 ccccacctcc ccgctgcaga aagcgctgtt ggccgccggc tccgcggcga 600

 tggcgctcta taacccctac cgccacggta aggccgcccg cgcctcgccc 650

 ccgtgggggg cggcttggag ccgtttcctg tgggtaactg gaacatagcc 700

 taggtcgggg tacccaaacc tggttgcagc tcgtaaccac tcggaacgtt 750

 tatgaaaatg cagattcctg gatcccacct aaacgcactg aatctgaatc 800

 tgaatctgca gtggagggag aaatgggcgt gaaaccgaaa gtctgtcttt 850

 aaactacttg ggagaatctg tcatgcagcc atattgagaa catctagact 900

 aaatagatga ttcataagta ccgatcagtt tataatatcc tactagaaag 950

 tcaactccga ggtcgaggac catgtctgcc tcgttccact gcatctgcag 1000

 ccttctggat agtgcctggc acatagttca gcgtctgacg tcagacgctg 1050

 aactatgtgg tgagaccaag agacaagcag atgctgctgg agacaagcca 1100

 tccatgcctg 1110

<210> 4690
<211> 46
<212> PRT
<213> Homo sapien

<400> 4690
 Met Ser Ala Ser Phe His Cys Ile Cys Ser Leu Leu Asp Ser Ala
   1               5                  10                  15

 Trp His Ile Val Gln Arg Leu Thr Ser Asp Ala Glu Leu Cys Gly
                  20                  25                  30

 Glu Thr Lys Arg Gln Ala Asp Ala Ala Gly Asp Lys Pro Ser Met
                  35                  40                  45

 Pro


<210> 4691
<211> 2059
<212> DNA
<213> Homo sapien

<400> 4691
 gcagtgatat aaatatattt ttttcttaga ctaaatatga gctgactatc 50

 tcttttgatg tgtgtacata ggtgtgagtg tgtgtgtatg cgtgcctgtc 100

 tgtgtgcggg tgtgtgtatg tgcatagcct catgcttagg actacccatg 150

 aatgttgtgg aatgctacac ctggagagtt ctggttttcc accagtttca 200

 agatgaagaa ctacatgata cagtggacct ggagaccatc cccttggaaa 250

 gacaacccag agatgttcag catcctgtat ctacacgcat cctgtatcta 300

 cacgtgtatt ttgtagctgt cacactaacc ttaataagaa ttctacagct 350

 ttggacagag gcattttcac cttaatggtg aagtaattta aaatataaat 400

 ccattcaggt gacaacccat catcaaaatt acaaattttc tgattgaact 450

 catctgaatc atcagttcct tgatggagag agagaaggag atggaatgtg 500

 tctggtaacc ccaaatggag tacaagtagc ctttgttttc ctgcataaat 550

 ggacttgttg aatgcgaacg aatatatgca attcatatac ttttggagat 600

 gaacgtagat atgtgtgtca gctttgagat ggtgtgtcct ggattaatac 650

 tttgtctccc aatatcacag aaaaatacat gccagtgact cttgaggtta 700

 aggtagttgg gatgaaatgg cctcaggcaa tttcacattc cctaattacc 750

 tggaaagttc tacagtaatt aatatgcagc taactcctgt tgccctcaca 800

 agagcatcag ccttctagaa tcggagctcc ggagtgtgaa gattcagtat 850

 tgatatgata tgtataccaa actccagcca acttactgcc atttttcata 900

 atctgagtgg ctgccttgct tatcctaagc tgtggttgca gaaaccgtgg 950

 ccatttatat aagctataac atcaaatcag ggaaaaatga ggaaaaaaaa 1000

 tagattctga accatttatt gttgaataag tagagaaaat catcaataaa 1050

 tatttattac attctgacag ggtgtgtggc attgtgttct atgccagagt 1100

 gacaaagttg attcacccct ttttggggac cttaatatat tttttaaggg 1150

 atgtgcctat gcattgatgc ctgaaaaata tgtataaaga aatgaggttg 1200

 actcttctga gcagttcatc ttttccagag gtaagggtag gaggccaact 1250

 tcaggatctg ggtctaagcc cgtgggcaag ccctggccga gtgagctcca 1300

 atgctaactc atgtgccgat ctctagagca gtgggaaact accccgctgc 1350

 accaaatcaa gtagcttcac cttgtgtatg caggccccaa gttatttttt 1400

 agcaatctta cgagtgaaat gttctggtgg gttgaaaaac gttcttattt 1450

 taaagaaagg ttgtgctcgc tacactgctg gtgtgtgcgt tctgagacct 1500

 cttgtattca atctgtgaag gatatgtgta ttaatccgta cacccgtata 1550

 gcctcaatat ttgtctgaag acacttaaat tctgacccat aaaggaaagt 1600

 tctagaagca atattttcac ttatttaaca ttctccaaac aacatcaagc 1650

 attgatacac actgaagagt gcgtttattt tttgtatcac tctaagtatg 1700

 ttggaatatg caaggactgt ggttcaaatt agaatgtata aggcatatta 1750

 taatttagtt catactgaaa aagaaattaa cagaacattg ttcggttcac 1800

 acgttccaaa atttgagtga tttctggagt tagacataga ttttctattt 1850

 tgttttaatt tgtcaaggta tttttcttcc cttcatgaac tttaggtaca 1900

 cataacttat gtcatttatt tatggtcttt tatacctagt ttgtaaaatt 1950

 gtaaaatagc aaactaaatg caaagagttt gcatttgaaa ataataaagt 2000

 agttaccgta tacaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2050

 aaaaaaaaa 2059

<210> 4692
<211> 105
<212> PRT
<213> Homo sapien

<400> 4692
 Met Cys Val His Arg Cys Glu Cys Val Cys Met Arg Ala Cys Leu
   1               5                  10                  15

 Cys Ala Gly Val Cys Met Cys Ile Ala Ser Cys Leu Gly Leu Pro
                  20                  25                  30

 Met Asn Val Val Glu Cys Tyr Thr Trp Arg Val Leu Val Phe His
                  35                  40                  45

 Gln Phe Gln Asp Glu Glu Leu His Asp Thr Val Asp Leu Glu Thr
                  50                  55                  60

 Ile Pro Leu Glu Arg Gln Pro Arg Asp Val Gln His Pro Val Ser
                  65                  70                  75

 Thr Arg Ile Leu Tyr Leu His Val Tyr Phe Val Ala Val Thr Leu
                  80                  85                  90

 Thr Leu Ile Arg Ile Leu Gln Leu Trp Thr Glu Ala Phe Ser Pro
                  95                 100                 105

<210> 4693
<211> 4675
<212> DNA
<213> Homo sapien

<400> 4693
 cagtagcatc gcccatttgc cattcactgc agtagcaaaa gtagtactct 50

 gtggtgggtt aatcggtttg aggcagctcc ttaaatgaac atttgtgttt 100

 catttttctg ttattttccc gaacatgaaa agacgataaa actgaaatgg 150

 aaaagatcta ttccagaggg gagcttcacc acttcattga cggctttaat 200

 gaagagaaaa gcaactggat gcgctatgtg aatccagcac actctccccg 250

 ggagcaaaac ctggctgcgt gtcagaacgg gatgaacatc tacttctaca 300

 ccattaagcc catccctgcc aaccaggaac ttcttgtgtg gtattgtcgg 350

 gactttgcag aaaggcttca ctacccttat cccggagagc tgacaatgat 400

 gaatctcaca caaacacaga gcagtctaaa gcaaccgagc actgagaaaa 450

 atgaactctg cccaaagaat gtcccaaaga gagagtacag cgtgaaagaa 500

 atcctaaaat tggactccaa cccctccaaa ggaaaggacc tctaccgttc 550

 taacatttca cccctcacat cagaaaagga cctcgatgac tttagaagac 600

 gtgggagccc cgaaatgccc ttctaccctc gggtcgttta ccccatccgg 650

 gcccctctgc cagaagactt tttgaaagct tccctggcct acgggatcga 700

 gagacccacg tacatcactc gctcccccat tccatcctcc accactccaa 750

 gcccctctgc aagaagcagc cccgaccaaa gcctcaagag ctccagccct 800

 cacagcagcc ctgggaatac ggtgtcccct gtgggccccg gctctcaaga 850

 gcaccgggac tcctacgctt acttgaacgc gtcctacggc acggaaggtt 900

 tgggctccta ccctggctac gcacccctgc cccacctccc gccagctttc 950

 atcccctcgt acaacgctca ctaccccaag ttcctcttgc ccccctacgg 1000

 catgaattgt aatggcctga gcgctgtgag cagcatgaat ggcatcaaca 1050

 actttggcct cttcccgagg ctgtgccctg tctacagcaa tctcctcggt 1100

 gggggcagcc tgccccaccc catgctcaac cccacttctc tcccgagctc 1150

 gctgccctca gatggagccc ggaggttgct ccagccggag catcccaggg 1200

 aggtgcttgt cccggcgccc cacagtgcct tctcctttac cggggccgcc 1250

 gccagcatga aggacaaggc ctgtagcccc acaagcgggt ctcccacggc 1300

 gggaacagcc gccacggcag aacatgtggt gcagcccaaa gctacctcag 1350

 cagcgatggc agcccccagc agcgacgaag ccatgaatct cattaaaaac 1400

 aaaagaaaca tgaccggcta caagaccctt ccctacccgc tgaagaagca 1450

 gaacggcaag atcaagtacg aatgcaacgt ttgcgccaag actttcggcc 1500

 agctctccaa tctgaaggtc cacctgagag tgcacagtgg agaacggcct 1550

 ttcaaatgtc agacttgcaa caagggcttt actcagctcg cccacctgca 1600

 gaaacactac ctggtacaca cgggagaaaa gccacatgaa tgccaggtct 1650

 gccacaagag atttagcagc accagcaatc tcaagaccca cctgcgactc 1700

 cattctggag agaaaccata ccaatgcaag gtgtgccctg ccaagttcac 1750

 ccagtttgtg cacctgaaac tgcacaagcg tctgcacacc cgggagcggc 1800

 cccacaagtg ctcccagtgc cacaagaact acatccatct ctgtagcctc 1850

 aaggttcacc tgaaagggaa ctgcgctgcg gccccggcgc ctgggctgcc 1900

 cttggaagat ctgacccgaa tcaatgaaga aatcgagaag tttgacatca 1950

 gtgacaatgc tgaccggctc gaggacgtgg aggatgacat cagtgtgatc 2000

 tctgtagtgg agaaggaaat tctggccgtg gtcagaaaag agaaagaaga 2050

 aactggcctg aaagtgtctt tgcaaagaaa catggggaat ggactcctct 2100

 cctcagggtg cagcctttat gagtcatcag atctacccct catgaagttg 2150

 cctcccagca acccactacc tctggtacct gtaaaggtca aacaagaaac 2200

 agttgaacca atggatcctt aagattttca gaaaacactt attttgtttc 2250

 ttaagttatg acttggtgag tcagggtgcc tgtaggaagt ggcttgtaca 2300

 taatcccagc tctgcaaagc tctctcgaca gcaaatggtt tcccctcacc 2350

 tctggaatta aagaaggaac tccaaagtta ctgaaatctc agggcatgaa 2400

 caaggcaaag gccatatata tatatatata tatatctgta tacatattat 2450

 atatacttat ttacacctgt gtctatatat ttgcccctgt gtattttgaa 2500

 tatttgtgtg gacatgtttg catagccttc ccattactaa gactattacc 2550

 tagtcataat tattttttca atgataatcc ttcataattt attatacaat 2600

 ttatcattca gaaagcaata attaaaaaag tttacaatga ctggaaagat 2650

 tccttgtaat ttgagtataa atgtattttt gtcttgtggc cattctttgt 2700

 agataatttc tgcacatctg tataagtacc taagatttag ttaaacaaat 2750

 atatgacttc agtcaacctc tctctctaat aatggtttga aaatgaggtt 2800

 tgggtaattg ccaatgttgg acagttgatg tgttcattcc tgggatccta 2850

 tcatttgaac agcattgtac ataacttggg ggtatgtgtg caggattacc 2900

 caagaataac ttaagtagaa gaaacaagaa agggaatctt gtatattttt 2950

 gttgatagtt catgtttttc ccccagccac aattttaccg gaagggtgac 3000

 aggaaggctt taccaacctg tctctccctc caaaagagca gaatcctccc 3050

 accgccctgc cctccccacc gagtcctgtg gccattcaga gcggccacat 3100

 gacttttgca tccattgtat tatcagaaaa tgtgaagaag aaaaaaatgc 3150

 catgttttaa aaccactgcg aaaatttccc caaagcatag gtggctttgt 3200

 gtgtgtgcga tttgggggct tgagtctggg tggtgttttg ttgttggttt 3250

 ttgttgcttt tttttttttt ttttttttaa tgtcaaaatt gcacaaacat 3300

 ggtgctctac caggaaggat tcgaggtaga taggctcagg ccacacttta 3350

 aaaacaaaca cacaaacaac aaaaaacggg tattctagtc atcttggggt 3400

 aaaagcgggt aatgaacatt cctatcccca acacatcaat tgtatttttt 3450

 ctgtaaaact cagattttcc tcagtatttg tgtttttaca ttttatggtt 3500

 aatttaatgg aagatgaaag ggcattgcaa agttgttcaa caacagttac 3550

 ctcattgagt gtgtccagta gtgcaggaaa tgatgtctta tctaatgatt 3600

 tgcttctcta gaggagaaac cgagtaaatg tgctccagca agatagactt 3650

 tgtgttattc tatcttttat tctgctaagc ccaaagatta catgttggtg 3700

 ttcaaagtgt agcaaaaaat gatgtatatt tataaatcta tttataccac 3750

 tatatcatat gtatatatat ttataaccac ttaaattgtg agccaagcca 3800

 tgtaaaagat ctactttttc taagggcaaa aaaaaaaaaa aaaaaaaaag 3850

 aacactcctt tctgagactt tgcttaatac ttggtgacct cacaatcacg 3900

 tcggtatgat tgggcaccct tgcctactgt aagagaccct aaaaccttgg 3950

 tgcagtggtg gggaccacaa aacaaccagg gaggaagaga tacatcattt 4000

 tttagtatta aggaccatct aagacagctc tatttttttt ttgccacttt 4050

 atgattatgt ggtcacaccc aagtcacaga aataaaaaac tgactttacc 4100

 gctgcaattt ttctgttttc ctccttacta aatactgata cattactcca 4150

 atctatttta taattatatt tgacattttg ttcacatcaa ctaatgttca 4200

 cctgtagaag agaacaaatt tcgaataatc cagggaaacc caagagcctt 4250

 actggtcttc tgtaacttcc aagactgaca gctttttatg tatcagtgtt 4300

 tgataaacac agtccttaac tgaaggtaaa ccaaagcatc acgttgacat 4350

 tagaccaaat acttttgatt cccaactact cgtttgttct ttttctcctt 4400

 ttgtgctttc ccatagtgag aatttttata aagacttctt gcttctctca 4450

 ccatccatcc ttctcttttc tgcctcttac atgtgaatgt tgagcccaca 4500

 atcaacagtg gttttatttt ttcctctact caaagttaaa actgaccaaa 4550

 gttactggct ttttactttg ctagaacaac aaactatctt atgtttacat 4600

 actggtttac aatgttattt atgtgcaaat tgtcaaaatg taaattaaat 4650

 ataaatgttc atgctttacc aaaat 4675

<210> 4694
<211> 691
<212> PRT
<213> Homo sapien

<400> 4694
 Met Glu Lys Ile Tyr Ser Arg Gly Glu Leu His His Phe Ile Asp
   1               5                  10                  15

 Gly Phe Asn Glu Glu Lys Ser Asn Trp Met Arg Tyr Val Asn Pro
                  20                  25                  30

 Ala His Ser Pro Arg Glu Gln Asn Leu Ala Ala Cys Gln Asn Gly
                  35                  40                  45

 Met Asn Ile Tyr Phe Tyr Thr Ile Lys Pro Ile Pro Ala Asn Gln
                  50                  55                  60

 Glu Leu Leu Val Trp Tyr Cys Arg Asp Phe Ala Glu Arg Leu His
                  65                  70                  75

 Tyr Pro Tyr Pro Gly Glu Leu Thr Met Met Asn Leu Thr Gln Thr
                  80                  85                  90

 Gln Ser Ser Leu Lys Gln Pro Ser Thr Glu Lys Asn Glu Leu Cys
                  95                 100                 105

 Pro Lys Asn Val Pro Lys Arg Glu Tyr Ser Val Lys Glu Ile Leu
                 110                 115                 120

 Lys Leu Asp Ser Asn Pro Ser Lys Gly Lys Asp Leu Tyr Arg Ser
                 125                 130                 135

 Asn Ile Ser Pro Leu Thr Ser Glu Lys Asp Leu Asp Asp Phe Arg
                 140                 145                 150

 Arg Arg Gly Ser Pro Glu Met Pro Phe Tyr Pro Arg Val Val Tyr
                 155                 160                 165

 Pro Ile Arg Ala Pro Leu Pro Glu Asp Phe Leu Lys Ala Ser Leu
                 170                 175                 180

 Ala Tyr Gly Ile Glu Arg Pro Thr Tyr Ile Thr Arg Ser Pro Ile
                 185                 190                 195

 Pro Ser Ser Thr Thr Pro Ser Pro Ser Ala Arg Ser Ser Pro Asp
                 200                 205                 210

 Gln Ser Leu Lys Ser Ser Ser Pro His Ser Ser Pro Gly Asn Thr
                 215                 220                 225

 Val Ser Pro Val Gly Pro Gly Ser Gln Glu His Arg Asp Ser Tyr
                 230                 235                 240

 Ala Tyr Leu Asn Ala Ser Tyr Gly Thr Glu Gly Leu Gly Ser Tyr
                 245                 250                 255

 Pro Gly Tyr Ala Pro Leu Pro His Leu Pro Pro Ala Phe Ile Pro
                 260                 265                 270

 Ser Tyr Asn Ala His Tyr Pro Lys Phe Leu Leu Pro Pro Tyr Gly
                 275                 280                 285

 Met Asn Cys Asn Gly Leu Ser Ala Val Ser Ser Met Asn Gly Ile
                 290                 295                 300

 Asn Asn Phe Gly Leu Phe Pro Arg Leu Cys Pro Val Tyr Ser Asn
                 305                 310                 315

 Leu Leu Gly Gly Gly Ser Leu Pro His Pro Met Leu Asn Pro Thr
                 320                 325                 330

 Ser Leu Pro Ser Ser Leu Pro Ser Asp Gly Ala Arg Arg Leu Leu
                 335                 340                 345

 Gln Pro Glu His Pro Arg Glu Val Leu Val Pro Ala Pro His Ser
                 350                 355                 360

 Ala Phe Ser Phe Thr Gly Ala Ala Ala Ser Met Lys Asp Lys Ala
                 365                 370                 375

 Cys Ser Pro Thr Ser Gly Ser Pro Thr Ala Gly Thr Ala Ala Thr
                 380                 385                 390

 Ala Glu His Val Val Gln Pro Lys Ala Thr Ser Ala Ala Met Ala
                 395                 400                 405

 Ala Pro Ser Ser Asp Glu Ala Met Asn Leu Ile Lys Asn Lys Arg
                 410                 415                 420

 Asn Met Thr Gly Tyr Lys Thr Leu Pro Tyr Pro Leu Lys Lys Gln
                 425                 430                 435

 Asn Gly Lys Ile Lys Tyr Glu Cys Asn Val Cys Ala Lys Thr Phe
                 440                 445                 450

 Gly Gln Leu Ser Asn Leu Lys Val His Leu Arg Val His Ser Gly
                 455                 460                 465

 Glu Arg Pro Phe Lys Cys Gln Thr Cys Asn Lys Gly Phe Thr Gln
                 470                 475                 480

 Leu Ala His Leu Gln Lys His Tyr Leu Val His Thr Gly Glu Lys
                 485                 490                 495

 Pro His Glu Cys Gln Val Cys His Lys Arg Phe Ser Ser Thr Ser
                 500                 505                 510

 Asn Leu Lys Thr His Leu Arg Leu His Ser Gly Glu Lys Pro Tyr
                 515                 520                 525

 Gln Cys Lys Val Cys Pro Ala Lys Phe Thr Gln Phe Val His Leu
                 530                 535                 540

 Lys Leu His Lys Arg Leu His Thr Arg Glu Arg Pro His Lys Cys
                 545                 550                 555

 Ser Gln Cys His Lys Asn Tyr Ile His Leu Cys Ser Leu Lys Val
                 560                 565                 570

 His Leu Lys Gly Asn Cys Ala Ala Ala Pro Ala Pro Gly Leu Pro
                 575                 580                 585

 Leu Glu Asp Leu Thr Arg Ile Asn Glu Glu Ile Glu Lys Phe Asp
                 590                 595                 600

 Ile Ser Asp Asn Ala Asp Arg Leu Glu Asp Val Glu Asp Asp Ile
                 605                 610                 615

 Ser Val Ile Ser Val Val Glu Lys Glu Ile Leu Ala Val Val Arg
                 620                 625                 630

 Lys Glu Lys Glu Glu Thr Gly Leu Lys Val Ser Leu Gln Arg Asn
                 635                 640                 645

 Met Gly Asn Gly Leu Leu Ser Ser Gly Cys Ser Leu Tyr Glu Ser
                 650                 655                 660

 Ser Asp Leu Pro Leu Met Lys Leu Pro Pro Ser Asn Pro Leu Pro
                 665                 670                 675

 Leu Val Pro Val Lys Val Lys Gln Glu Thr Val Glu Pro Met Asp
                 680                 685                 690

 Pro


<210> 4695
<211> 4060
<212> DNA
<213> Homo sapien

<400> 4695
 agcggggggg gagggggggc cgacttcctg gggccgcccg tgaggatgtc 50

 gcgaccgccc ccgggtgccc ctcagcccca gagacgccgc cgcggcggag 100

 tccgcagcct ccctgcctga ggcgtccgcg gccgggatcc ggcccctccc 150

 ctcgcctcct ctcctaggtg ccggccggga gggcggccgc agcagatttt 200

 atcatgtggg caacctgctg caactggttc tgcctggatg gacagcctga 250

 ggaggtccca ccaccccagg gagccaggat gcaggcctat tccaaccctg 300

 ggtacagctc cttcccttcc ccaacaggct tggaaccaag ctgcaagtcc 350

 tgtggggctc actttgcaaa cacggccagg aagcagacct gcttggactg 400

 taagaaaaat ttttgcatga cctgttcgag ccaagtaggg aatgggcccc 450

 gcctctgcct tctctgccaa cggtttcgag ctacagcctt tcagcgagag 500

 gagctcatga agatgaaggt gaaggacttg agggactatc tcagcctcca 550

 tgacatctct accgaaatgt gccgggagaa aggagagctg gtgctcttgg 600

 tccttggcca gcagcctgta atctcccagg aggacaggac tcgtgcctcc 650

 accttgtccc cagactttcc tgagcagcag gccttcctga cccagcctca 700

 ctccagcatg gttccaccta cctcacccaa cctcccctct tcatctgcac 750

 aagccacctc tgttccccca gcccaggttc aggagaatca gcagtctatt 800

 gactcagagg acagctttgt cccaggccga agggcctctc tgtctgacct 850

 gactgacctg gaggacattg aaggcctgac agtgcggcag ctgaaagaga 900

 tcttggctcg caactttgtc aactacaagg gctgctgtga gaagtgggag 950

 ctgatggaga gagtgacccg gctatacaag gatcagaaag gactccagca 1000

 cctgggggga gcagtaccat caggcttgga ggagaacctg tgtaagatct 1050

 gcatggactc acccattgac tgtgttcttc tggagtgtgg ccacatggta 1100

 acctgtacca agtgtggcaa gcgcatgaat gaatgtccca tctgccggca 1150

 gtatgtaatc cgagctgtgc atgtcttccg gtcctgagag cttgcatcgg 1200

 tttcttcagt gccttacagg gaaatagcct ggggtgtctg ggctcagggt 1250

 tggccagctt gcagaggagc aagctagtag aaatattgca gggttcccaa 1300

 aaccaggtca agcaagatgc catgtcaccc ctgagcatgc ctgtcttccc 1350

 aggggtgtac ctcttggctg gcaaagccca aggccagtgg gaacttgtat 1400

 aaatcacatg ggtatgttct tggttcagtg atcttggagt gatgatggta 1450

 actgatgaac agagaacttt ccagaacttg ggtcctgtct tcctccctga 1500

 acctagacag tttcacccct cctcctgtac ccaacccatc cccaccccat 1550

 atgggagatg cttgcccatg tgtttcatca atcagaagtc ctcctcccca 1600

 gcacattcgg atttaaattt ctggtctctc cggctttctg tgctttaact 1650

 atctttgcta aagtctcttg ctacattgcc taaatccatt tgtttctttg 1700

 gaccaaaaat gttagtttac cagaccgata gtggtcctta ggacagattt 1750

 tagaccagta aacttatctt tggtgagaaa tgaaatacaa atgctataga 1800

 aaaatttcaa agttgttaaa agccacttca ttaaatgctg ggattggaag 1850

 ctgttggtct cctgacctga ctctgggagc caacaaaaca tcaggctccc 1900

 aaactgctgg gaaatttgtt tctgtctgca agggatagtg cgtgcataat 1950

 ccctgctgct gcttctcttg ggacctgatt tgcaccatcc ttagtttatg 2000

 cggaaagggg aagcaatggg tggaggcagt ggccttctcc ttaattttgg 2050

 cttggcttct gatccttttc ccaactagaa gtcttaagcc acttttcgct 2100

 gaaaatgaaa tccctccctt atccatggta gttttaaatt tggtttcatt 2150

 gaagaaatag atttaggcaa agagcctgtg ctcttctctg gccagactgc 2200

 tgttgaagtt cctggagagc aaatgttaag acagagcact taagagcttt 2250

 caggaggtac tgaatgagac tggattctgt tgtaagccga cagttcaagt 2300

 ctttatttcc caggttggtg gggagtgagg agaccctact ttcattccct 2350

 ttcctagccc actgattttt gggggcaggt cagggagaaa gcattttttt 2400

 tttttttttt gagtctcact ctgttgccca ggctggagtg cagtggtaca 2450

 gtcttggctt actgcaacct ccacctccca ggttcaagct attctcctgc 2500

 cttagcctcc agagtagctg ggattatagg cgcccaccac cacaccaggc 2550

 taatttttgt atttttagta gagacggggt tttaccatgt tcaccaggct 2600

 ggtcttgaaa tcttgacctt atgatccgcc cgcctcagct tcccaaagtg 2650

 ctgggattac aggcgtgagc caccacaccc agcaggagaa accattttct 2700

 aggctcttta ggaaggacca tgcaatgagt aggtgatgta tttgagccct 2750

 cacagtcttt acacccctag aggagctgga ggacttaaga gtttgctgca 2800

 gaagcgtggc caagcacaaa acacatgatc aggaaagcag agtgttttcc 2850

 cattaccaat ggatgaacta tgcaaaccct aaacgccttg gcagacacct 2900

 cccacccctt acccctccca tgcagctgaa aaatctgaga ctagaaccaa 2950

 tcatgactct ggatggcaga gggaaacctc taaagggact tattacattg 3000

 gtacagacat atttatgctt tcttccatca ccaaccacta aacccctttg 3050

 gaggaatgaa ataactgcat aaactagtca actgaacact gggccactta 3100

 cctcaatgtt atacaaagtc ctggatgatt tgattctgaa ccacagcctt 3150

 tgcaggagtt gggggaatca gatttgctca tgaagacatc cctttccact 3200

 tttgtcatgg gcagtaaata ctatagttta caatgcctac caattagcaa 3250

 aggatcattc cttcagctac tcagttcctc tgtaaaacag gtctatgtat 3300

 gtgcaattca gctaagatct agcagtaact taagggcaga agctggctct 3350

 ctacttacaa cctgctttct ctgctgaagc cttacctcct cttcagtttc 3400

 cctcctagac acaaatcgaa aataatatac tgatagctgg ttagtaacct 3450

 cagtaagaat taaaactgag gttgtttact cattttgcct ttaaatcttt 3500

 tatccccttt tggtgaaggt ttccctttag gaaaaaaggt gtcaaacaac 3550

 cctgattttt tttttttttg catcattttt attacaccaa attaaagttg 3600

 ggagttccaa gatcccattc cagttaatat ttaaccaagg tctaaaattt 3650

 gatttttttt aaatctttga atcctccctt ctgcccctca tggatccttg 3700

 gttttaatga tatggaaaca tctaattctt agaattattc cgtagctttt 3750

 gctgattact ctgagatttc agttaggact tgtttcaaaa gacagatagc 3800

 tgactggttc ataatacatt ggaatagttg gatccaaact aataagaata 3850

 agctgtacag gaactagtgc tcaatataca ttgtataaat ttgtggaaat 3900

 ctcttggatg tgaattgtta cttcaagtgg cttttattaa gattttctca 3950

 gacttacttg gaggttaaag caaacccaaa tgtgtattat tttgttacag 4000

 agctctgctt tataattttg taataaagtt tcaatacaga caccaaaaaa 4050

 aaaaaaaaaa 4060

<210> 4696
<211> 327
<212> PRT
<213> Homo sapien

<400> 4696
 Met Trp Ala Thr Cys Cys Asn Trp Phe Cys Leu Asp Gly Gln Pro
   1               5                  10                  15

 Glu Glu Val Pro Pro Pro Gln Gly Ala Arg Met Gln Ala Tyr Ser
                  20                  25                  30

 Asn Pro Gly Tyr Ser Ser Phe Pro Ser Pro Thr Gly Leu Glu Pro
                  35                  40                  45

 Ser Cys Lys Ser Cys Gly Ala His Phe Ala Asn Thr Ala Arg Lys
                  50                  55                  60

 Gln Thr Cys Leu Asp Cys Lys Lys Asn Phe Cys Met Thr Cys Ser
                  65                  70                  75

 Ser Gln Val Gly Asn Gly Pro Arg Leu Cys Leu Leu Cys Gln Arg
                  80                  85                  90

 Phe Arg Ala Thr Ala Phe Gln Arg Glu Glu Leu Met Lys Met Lys
                  95                 100                 105

 Val Lys Asp Leu Arg Asp Tyr Leu Ser Leu His Asp Ile Ser Thr
                 110                 115                 120

 Glu Met Cys Arg Glu Lys Gly Glu Leu Val Leu Leu Val Leu Gly
                 125                 130                 135

 Gln Gln Pro Val Ile Ser Gln Glu Asp Arg Thr Arg Ala Ser Thr
                 140                 145                 150

 Leu Ser Pro Asp Phe Pro Glu Gln Gln Ala Phe Leu Thr Gln Pro
                 155                 160                 165

 His Ser Ser Met Val Pro Pro Thr Ser Pro Asn Leu Pro Ser Ser
                 170                 175                 180

 Ser Ala Gln Ala Thr Ser Val Pro Pro Ala Gln Val Gln Glu Asn
                 185                 190                 195

 Gln Gln Ser Ile Asp Ser Glu Asp Ser Phe Val Pro Gly Arg Arg
                 200                 205                 210

 Ala Ser Leu Ser Asp Leu Thr Asp Leu Glu Asp Ile Glu Gly Leu
                 215                 220                 225

 Thr Val Arg Gln Leu Lys Glu Ile Leu Ala Arg Asn Phe Val Asn
                 230                 235                 240

 Tyr Lys Gly Cys Cys Glu Lys Trp Glu Leu Met Glu Arg Val Thr
                 245                 250                 255

 Arg Leu Tyr Lys Asp Gln Lys Gly Leu Gln His Leu Gly Gly Ala
                 260                 265                 270

 Val Pro Ser Gly Leu Glu Glu Asn Leu Cys Lys Ile Cys Met Asp
                 275                 280                 285

 Ser Pro Ile Asp Cys Val Leu Leu Glu Cys Gly His Met Val Thr
                 290                 295                 300

 Cys Thr Lys Cys Gly Lys Arg Met Asn Glu Cys Pro Ile Cys Arg
                 305                 310                 315

 Gln Tyr Val Ile Arg Ala Val His Val Phe Arg Ser
                 320                 325

<210> 4697
<211> 1320
<212> DNA
<213> Homo sapien

<400> 4697
 caggtaaaaa acaaacaaac aaaggtttag atgttagata tattttacaa 50

 ttaccacacc agtcttttta ctacagcatc tagtaacaca tttaccatag 100

 atttagatgg aaattttcat cccataagcc tttgttagta tttttaaaat 150

 tgaatactca ataaatagtg gccaagttga atctcttaga ggaatctcac 200

 tcaaactaca gtcatatttt ccaataggcc ccacaaaaat cattgctcta 250

 gagtaattta atatatttat ccacctcttt agacacttag gtaagtataa 300

 taatacaagt tttgtgcgtg tgtgtgtatt gtgtaccttg tggcttcttg 350

 cccagtttct gcaacacctg aagctgatgc atgtttaatg taaataatgt 400

 ccagcaatgt tacaaatgtt gacttttatg tgcccatcag ggaaaaaaaa 450

 gatgaatgtt attgtagagg aaattttcat tctggaaaaa atgcatacta 500

 tttgaatatt attttcatga tttccacaga tattacacac agatattata 550

 ttccaaggat tatgtttcaa agtcatcaaa aatagaaaat acatctatat 600

 ttctaactga aaataataac agtaagtagc ccagctttgg ggaaatgtga 650

 taaaaatatt aatgaccatc acaactcatt aaaagcataa attgtgcaat 700

 gatttaaact acatgttctt catatgaatg tgtgtagaaa tatagacaca 750

 ttggataaat gctatttaaa gtctgagtgc gttggtaact gattcagtca 800

 tctgtaggtt gaagtgatta cttttatctg ccttcatagt gagaattaga 850

 tttctattct ttgtaaagca gggaatatag attgtgcatg gagtaaaaga 900

 attcaatcct tattaataat gatggtagct gcgctgcaga aaagaaagcc 950

 tgtcagagta acttattcag ttttacatca taatcagagg tgtgtccatc 1000

 tctgttgaag gcagaattaa aaaccccttc aacattttta aaataataga 1050

 tgaaaaacat ctcaaagtct cctttaaaat ttgaattgac gattccacat 1100

 aaaaggaagg gaccaaaaat atcttaaaga aatacttcac gatggaagtg 1150

 atgttttaag tgaaatttca tcaaggagaa gtttttccaa aaagtatttt 1200

 tacctcagga agaatctcat tagtttattc tgtaaatagt tcctagtaaa 1250

 atgataaaga cttgattttt caaaaacaat aaaaaactta cacggtttaa 1300

 tctaaaaaaa aaaaaaaaaa 1320

<210> 4698
<211> 26
<212> PRT
<213> Homo sapien

<400> 4698
 Gly Lys Lys Gln Thr Asn Lys Gly Leu Asp Val Arg Tyr Ile Leu
   1               5                  10                  15

 Gln Leu Pro His Gln Ser Phe Tyr Tyr Ser Ile
                  20                  25

<210> 4699
<211> 4395
<212> DNA
<213> Homo sapien

<400> 4699
 ggcgaggatg gggagcaatg caaagctctg ctcgcccccc atctcacccc 50

 ccaagcggat actggtcttc tcgtcggatt gcccatgcac ttgttgcaga 100

 aacagccaag gccctggctg tggagaatgc tgaaggaaga agacgcagaa 150

 gcaggacgac cctgaaagat tcagcctctt catcctcaaa caggaccagg 200

 cctcctcttc ccacctgtcc agcagcatga aagcagcatg attggccgac 250

 cgcaggagaa gcccccagaa ccaggccccc aactcagcca tctgcggagg 300

 tcaaggtgtg agcgacgtct cctcaccaca gtgctgtgtg gtctatacct 350

 cagccaggga gaggatgtga aaccccccgc cctgcacatg agtggtacag 400

 gccaacagga acacctggct ccagccacgt tcacagacat gtcagccgtg 450

 gagtagtgct gacacttttc tctcagcttc tcagggtttc agtccttttg 500

 ggtttgtttt atttaccttt tttatggttt tgtggctgga cgttcacaac 550

 caaggcagac agcatgggtg accagcaact gtacaagacc aaccatgtgg 600

 cccatggtag tgagaacctt ttctaccaac agccaccact tggcgtccac 650

 agcgggctga accacaacta tgggaatgca gttacagggg gcggaatgga 700

 tgcccctcag gcctcgccaa tctcccccca cttccctcaa gatacacggg 750

 atggtctggg cttgcctgtt ggctccaaaa accttggcca aatggatacc 800

 tcgaggcagg gagggtgggg aagtcatgca gggcctggaa accatgtcca 850

 gctacgtgga aacctggcca actcaaacat gatgtggggg gcaccagccc 900

 aggctgagcc cactgatggc taccaataca cctactccca ggccagcgag 950

 atccggaccc agaagcttac cagcggtgtc ttacacaagc tggactcttt 1000

 cacccaggtg tttgccaacc aaaacctgcg aattcaggtc aacaatatgg 1050

 cccaggtgct gcacactcag tcagcagtga tggatggagc ccctgacagt 1100

 gctctccgcc agctgctgtc tcagaagccc atggagcccc cagcaccggc 1150

 tatcccttcc cgctaccagc aggtgcccca gcagcctcac cctggtttca 1200

 ctggtgggct gtccaaacca gctcttcagg tcgggcagca ccctacccaa 1250

 gggcacctgt attatgacta ccagcagcct ctggctcagg tgccagtgca 1300

 gggaggacag ccactgcagg ccccacagat gctgtcacag cacatgcaac 1350

 agatgcagca gcaccagtat tacccaccgc agcaacagca gcaagccggg 1400

 caacagcgta tctccatgca agaaatacag acgcagccgc aacaaattcg 1450

 cccatcacag ccacagccgc cgccacagca gcagcagccg cagcagctac 1500

 agctgcagca gcggcagggt tcaatgcaga tacctcagta ttatcagccc 1550

 caacccatga tgcagcactt gcaagagcag cagcagcaac agatgcacct 1600

 gcagcctcct tcttatcaca gggaccctca ccagtatacc ccagagcagg 1650

 cacacactgt ccagctgatt cccctgggct ccatgtccca gtactactac 1700

 caggagcccc agcagcccta cagccacccc ctctaccagc agagccacct 1750

 gtcccagcac cagcagcgtg aggacagtca gctgaagacc tactctagtg 1800

 acagacaggc ccaggccatg ctgagctccc atggggacct ggggcctcct 1850

 gacacaggaa tgggagaccc agcgagctca gatctgaccc gggtcagcag 1900

 caccctcccc catcgccccc tcctatcccc cagtgggatc cacctcaaca 1950

 acatggggcc tcagcatcag cagctgtctc ccagtgccat gtggccccag 2000

 atgcacctac ctgatgggag agcccagcca gggtcccctg agtcaagtgg 2050

 ccaacccaaa ggagcgtttg gggagcagtt tgatgccaag aacaagctga 2100

 catgctccat ctgcctgaag gagttcaaga acctgcctgc cctgaatggc 2150

 cacatgcggt cccacggggg aatgagggcc tcccccaacc tcaaacagga 2200

 ggaaggagag aaggtcctgc cgcctcagcc ccagccacca ctgccgcctc 2250

 cgcctccgcc tccgccgcca ccacagctcc ctcccgaggc agaaagcctc 2300

 acgcctatgg tcatgcccgt gtctgtccct gtcaagcttc tcccgcccaa 2350

 gcccagctct caggggttca ccaacagcac cgttgccgcc ccctccgcca 2400

 gagacaagcc agccagctcg atgtcggacg acgagatgcc tgtgctcgaa 2450

 atccccagga agcatcagcc gagtgtgccc aaagccgagg agcccctcaa 2500

 gaccgtgcag gagaagaaaa agttccggca ccggccggaa cctctcttca 2550

 tcccgccgcc gccctcctac aacccgaacc ccgctgcctc ctactcgggc 2600

 gccaccctgt accagagcca gctgcgctcc ccgcgcgtcc tcggggacca 2650

 cctgctcctg gaccccaccc acgagctgcc cccttacacg cccccaccca 2700

 tgctgagccc ggtgcgccag ggctcggggc tcttcagcaa tgtcctcatc 2750

 tccggccacg gccctggcgc ccacccgcag ctgcccctga cgcccctgac 2800

 gcccacacca cgggtgctgc tgtgtcgctc caacagcatc gatggcagca 2850

 acgtgacggt caccccaggg cctggagagc agactgtaga tgttgaacca 2900

 cgcatcaaca ttggcttgag attccaagca gaaatccctg aactccaaga 2950

 tatctctgcc ctggcccagg acacacacaa ggccacactg gtatggaagc 3000

 cctggccaga actagaaaac catgacctcc agcaaagagt ggagaatctt 3050

 ctgaatttgt gctgttccag tgcattgcca ggtggaggga ccaattctga 3100

 atttgctttg cactctctgt ttgaggccaa aggtgatgtg atggttgctc 3150

 tggaaatgct gctactgcgg aagcctgtca ggttaaaatg tcatccttta 3200

 gcaaattacc actatgccgg ttcggacaag tggacctccc tagaaagaaa 3250

 actgtttaac aaagcactag ccacttacag caaagacttt atttttgtac 3300

 agaagatggt gaagtccaag acggtggctc agtgcgtgga gtactactac 3350

 acgtggaaaa agatcatgcg gctggggcgg aaacaccgga cacgcctggc 3400

 agaaatcatc gacgattgtg tgacaagtga agaagaagaa gagttagagg 3450

 aggaggagga ggaggacccg gaagaagata ggaaatccac aaaagaagaa 3500

 gagagtgagg tgccgaagtc cccggagcca ccacccgtcc ccgtcctggc 3550

 tcccacggag gggccgcccc tgcaggccct gggccagccc tcaggctcct 3600

 tcatctgtga aatgcccaac tgtggggctg tgttcagctc ccgacaggca 3650

 ctgaatggcc atgcccgcat ccacgggggc accaaccagg tgaccaaggc 3700

 ccgaggtgcc atcccctctg ggaagcagaa gcctggtggc acccagagtg 3750

 ggtactgttc ggtaaagagc tcaccctctc acagcaccac cagcggcgag 3800

 acagacccca ccaccatctt cccctgcaag gagtgtggca aagtcttctt 3850

 caagatcaaa agccgaaatg cacacatgaa aactcacagg cagcaggagg 3900

 aacaacagag gcaaaaggct cagaaggcgg cttttgcagc tgagatggca 3950

 gccacgattg agaggactac ggggcccgtg ggggcgccgg ggctgctgcc 4000

 cctggaccag ctgagtctga tcaaacccat caaggatgtg gacatcctcg 4050

 acgacgacgt cgtccagcag ttgggaggtg tcatggaaga ggctgaagtt 4100

 gtggacaccg atcttctctt ggatgatcaa gattcagtct tgcttcaggg 4150

 tgacgcagaa ctataaagcc ctgtgtgtca cttagagaca gtgaaaaccc 4200

 acggcctcca tcttcattaa tcaggaaacc tggactgcct gcttgttttg 4250

 taaccctttt aaactacctg ttttaaaagt ggtcatttta ttcaggttta 4300

 gaaaaaaaaa tcctatttct tttcttttat ttaaaaaaat ttgtttttgt 4350

 ggggggttgg gggaataaat aattggcaca actaaaaaaa aaaaa 4395

<210> 4700
<211> 1200
<212> PRT
<213> Homo sapien

<400> 4700
 Met Gly Asp Gln Gln Leu Tyr Lys Thr Asn His Val Ala His Gly
   1               5                  10                  15

 Ser Glu Asn Leu Phe Tyr Gln Gln Pro Pro Leu Gly Val His Ser
                  20                  25                  30

 Gly Leu Asn His Asn Tyr Gly Asn Ala Val Thr Gly Gly Gly Met
                  35                  40                  45

 Asp Ala Pro Gln Ala Ser Pro Ile Ser Pro His Phe Pro Gln Asp
                  50                  55                  60

 Thr Arg Asp Gly Leu Gly Leu Pro Val Gly Ser Lys Asn Leu Gly
                  65                  70                  75

 Gln Met Asp Thr Ser Arg Gln Gly Gly Trp Gly Ser His Ala Gly
                  80                  85                  90

 Pro Gly Asn His Val Gln Leu Arg Gly Asn Leu Ala Asn Ser Asn
                  95                 100                 105

 Met Met Trp Gly Ala Pro Ala Gln Ala Glu Pro Thr Asp Gly Tyr
                 110                 115                 120

 Gln Tyr Thr Tyr Ser Gln Ala Ser Glu Ile Arg Thr Gln Lys Leu
                 125                 130                 135

 Thr Ser Gly Val Leu His Lys Leu Asp Ser Phe Thr Gln Val Phe
                 140                 145                 150

 Ala Asn Gln Asn Leu Arg Ile Gln Val Asn Asn Met Ala Gln Val
                 155                 160                 165

 Leu His Thr Gln Ser Ala Val Met Asp Gly Ala Pro Asp Ser Ala
                 170                 175                 180

 Leu Arg Gln Leu Leu Ser Gln Lys Pro Met Glu Pro Pro Ala Pro
                 185                 190                 195

 Ala Ile Pro Ser Arg Tyr Gln Gln Val Pro Gln Gln Pro His Pro
                 200                 205                 210

 Gly Phe Thr Gly Gly Leu Ser Lys Pro Ala Leu Gln Val Gly Gln
                 215                 220                 225

 His Pro Thr Gln Gly His Leu Tyr Tyr Asp Tyr Gln Gln Pro Leu
                 230                 235                 240

 Ala Gln Val Pro Val Gln Gly Gly Gln Pro Leu Gln Ala Pro Gln
                 245                 250                 255

 Met Leu Ser Gln His Met Gln Gln Met Gln Gln His Gln Tyr Tyr
                 260                 265                 270

 Pro Pro Gln Gln Gln Gln Gln Ala Gly Gln Gln Arg Ile Ser Met
                 275                 280                 285

 Gln Glu Ile Gln Thr Gln Pro Gln Gln Ile Arg Pro Ser Gln Pro
                 290                 295                 300

 Gln Pro Pro Pro Gln Gln Gln Gln Pro Gln Gln Leu Gln Leu Gln
                 305                 310                 315

 Gln Arg Gln Gly Ser Met Gln Ile Pro Gln Tyr Tyr Gln Pro Gln
                 320                 325                 330

 Pro Met Met Gln His Leu Gln Glu Gln Gln Gln Gln Gln Met His
                 335                 340                 345

 Leu Gln Pro Pro Ser Tyr His Arg Asp Pro His Gln Tyr Thr Pro
                 350                 355                 360

 Glu Gln Ala His Thr Val Gln Leu Ile Pro Leu Gly Ser Met Ser
                 365                 370                 375

 Gln Tyr Tyr Tyr Gln Glu Pro Gln Gln Pro Tyr Ser His Pro Leu
                 380                 385                 390

 Tyr Gln Gln Ser His Leu Ser Gln His Gln Gln Arg Glu Asp Ser
                 395                 400                 405

 Gln Leu Lys Thr Tyr Ser Ser Asp Arg Gln Ala Gln Ala Met Leu
                 410                 415                 420

 Ser Ser His Gly Asp Leu Gly Pro Pro Asp Thr Gly Met Gly Asp
                 425                 430                 435

 Pro Ala Ser Ser Asp Leu Thr Arg Val Ser Ser Thr Leu Pro His
                 440                 445                 450

 Arg Pro Leu Leu Ser Pro Ser Gly Ile His Leu Asn Asn Met Gly
                 455                 460                 465

 Pro Gln His Gln Gln Leu Ser Pro Ser Ala Met Trp Pro Gln Met
                 470                 475                 480

 His Leu Pro Asp Gly Arg Ala Gln Pro Gly Ser Pro Glu Ser Ser
                 485                 490                 495

 Gly Gln Pro Lys Gly Ala Phe Gly Glu Gln Phe Asp Ala Lys Asn
                 500                 505                 510

 Lys Leu Thr Cys Ser Ile Cys Leu Lys Glu Phe Lys Asn Leu Pro
                 515                 520                 525

 Ala Leu Asn Gly His Met Arg Ser His Gly Gly Met Arg Ala Ser
                 530                 535                 540

 Pro Asn Leu Lys Gln Glu Glu Gly Glu Lys Val Leu Pro Pro Gln
                 545                 550                 555

 Pro Gln Pro Pro Leu Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro
                 560                 565                 570

 Gln Leu Pro Pro Glu Ala Glu Ser Leu Thr Pro Met Val Met Pro
                 575                 580                 585

 Val Ser Val Pro Val Lys Leu Leu Pro Pro Lys Pro Ser Ser Gln
                 590                 595                 600

 Gly Phe Thr Asn Ser Thr Val Ala Ala Pro Ser Ala Arg Asp Lys
                 605                 610                 615

 Pro Ala Ser Ser Met Ser Asp Asp Glu Met Pro Val Leu Glu Ile
                 620                 625                 630

 Pro Arg Lys His Gln Pro Ser Val Pro Lys Ala Glu Glu Pro Leu
                 635                 640                 645

 Lys Thr Val Gln Glu Lys Lys Lys Phe Arg His Arg Pro Glu Pro
                 650                 655                 660

 Leu Phe Ile Pro Pro Pro Pro Ser Tyr Asn Pro Asn Pro Ala Ala
                 665                 670                 675

 Ser Tyr Ser Gly Ala Thr Leu Tyr Gln Ser Gln Leu Arg Ser Pro
                 680                 685                 690

 Arg Val Leu Gly Asp His Leu Leu Leu Asp Pro Thr His Glu Leu
                 695                 700                 705

 Pro Pro Tyr Thr Pro Pro Pro Met Leu Ser Pro Val Arg Gln Gly
                 710                 715                 720

 Ser Gly Leu Phe Ser Asn Val Leu Ile Ser Gly His Gly Pro Gly
                 725                 730                 735

 Ala His Pro Gln Leu Pro Leu Thr Pro Leu Thr Pro Thr Pro Arg
                 740                 745                 750

 Val Leu Leu Cys Arg Ser Asn Ser Ile Asp Gly Ser Asn Val Thr
                 755                 760                 765

 Val Thr Pro Gly Pro Gly Glu Gln Thr Val Asp Val Glu Pro Arg
                 770                 775                 780

 Ile Asn Ile Gly Leu Arg Phe Gln Ala Glu Ile Pro Glu Leu Gln
                 785                 790                 795

 Asp Ile Ser Ala Leu Ala Gln Asp Thr His Lys Ala Thr Leu Val
                 800                 805                 810

 Trp Lys Pro Trp Pro Glu Leu Glu Asn His Asp Leu Gln Gln Arg
                 815                 820                 825

 Val Glu Asn Leu Leu Asn Leu Cys Cys Ser Ser Ala Leu Pro Gly
                 830                 835                 840

 Gly Gly Thr Asn Ser Glu Phe Ala Leu His Ser Leu Phe Glu Ala
                 845                 850                 855

 Lys Gly Asp Val Met Val Ala Leu Glu Met Leu Leu Leu Arg Lys
                 860                 865                 870

 Pro Val Arg Leu Lys Cys His Pro Leu Ala Asn Tyr His Tyr Ala
                 875                 880                 885

 Gly Ser Asp Lys Trp Thr Ser Leu Glu Arg Lys Leu Phe Asn Lys
                 890                 895                 900

 Ala Leu Ala Thr Tyr Ser Lys Asp Phe Ile Phe Val Gln Lys Met
                 905                 910                 915

 Val Lys Ser Lys Thr Val Ala Gln Cys Val Glu Tyr Tyr Tyr Thr
                 920                 925                 930

 Trp Lys Lys Ile Met Arg Leu Gly Arg Lys His Arg Thr Arg Leu
                 935                 940                 945

 Ala Glu Ile Ile Asp Asp Cys Val Thr Ser Glu Glu Glu Glu Glu
                 950                 955                 960

 Leu Glu Glu Glu Glu Glu Glu Asp Pro Glu Glu Asp Arg Lys Ser
                 965                 970                 975

 Thr Lys Glu Glu Glu Ser Glu Val Pro Lys Ser Pro Glu Pro Pro
                 980                 985                 990

 Pro Val Pro Val Leu Ala Pro Thr Glu Gly Pro Pro Leu Gln Ala
                 995                1000                1005

 Leu Gly Gln Pro Ser Gly Ser Phe Ile Cys Glu Met Pro Asn Cys
                1010                1015                1020

 Gly Ala Val Phe Ser Ser Arg Gln Ala Leu Asn Gly His Ala Arg
                1025                1030                1035

 Ile His Gly Gly Thr Asn Gln Val Thr Lys Ala Arg Gly Ala Ile
                1040                1045                1050

 Pro Ser Gly Lys Gln Lys Pro Gly Gly Thr Gln Ser Gly Tyr Cys
                1055                1060                1065

 Ser Val Lys Ser Ser Pro Ser His Ser Thr Thr Ser Gly Glu Thr
                1070                1075                1080

 Asp Pro Thr Thr Ile Phe Pro Cys Lys Glu Cys Gly Lys Val Phe
                1085                1090                1095

 Phe Lys Ile Lys Ser Arg Asn Ala His Met Lys Thr His Arg Gln
                1100                1105                1110

 Gln Glu Glu Gln Gln Arg Gln Lys Ala Gln Lys Ala Ala Phe Ala
                1115                1120                1125

 Ala Glu Met Ala Ala Thr Ile Glu Arg Thr Thr Gly Pro Val Gly
                1130                1135                1140

 Ala Pro Gly Leu Leu Pro Leu Asp Gln Leu Ser Leu Ile Lys Pro
                1145                1150                1155

 Ile Lys Asp Val Asp Ile Leu Asp Asp Asp Val Val Gln Gln Leu
                1160                1165                1170

 Gly Gly Val Met Glu Glu Ala Glu Val Val Asp Thr Asp Leu Leu
                1175                1180                1185

 Leu Asp Asp Gln Asp Ser Val Leu Leu Gln Gly Asp Ala Glu Leu
                1190                1195                1200

<210> 4701
<211> 3579
<212> DNA
<213> Homo sapien

<400> 4701
 gagaccatat ggactgcaaa gcctaaaatc tatctggacc cttacagtaa 50

 aacaatgacc ctgggttttc atggcacccc aatgcctttt tggtgacttg 100

 caggaataca gattcctata ttcccgtttg tttttttttt tttctcctta 150

 gcttaaggtt cgtattccca tttgcttctg agaaagttag gaaaattttg 200

 ttttatgttg cagatgctct cacaacataa ttgtgctgga gatagataca 250

 cttagtgaaa ttttcctaca gaactaaaaa cgcaaattgc atcactccta 300

 aaaaaaagaa atttagagta tgaattgagt tggttgagag tagaattaaa 350

 aagatttcta gcactttgag catgttttaa gaaatttgat ccttacattt 400

 aaaattatgt aaatgacatc tttcactggc atttgctcac atttaagtca 450

 atctacagct gttacttact aagctaagaa ataagaagat ccctatggtt 500

 ctgaatctct cataatattc tgaagtaatt tatatcaatt gaattttcat 550

 taatcatttt aggaaatatt atgttttatt ttgtggcatt atatgacaat 600

 gactttctca acaatagctc agggaatacg caaacagcca gctcttttat 650

 gtaagaaagc cattttctaa tccccacgct ttcctgagtg ttacgtattt 700

 tatttctttg aaaagagagg gccttgagta aatgctttcg tttgctttcc 750

 ttacatattt agaaatccaa gaagggccct tgtcttagtc tatttctgtc 800

 acagagaaat tgttcattcc aaaatatcca ccttaaggga agctagtgac 850

 cgagatatgg agaaaaacat aggcattcat gacctttgtg tttccgtttg 900

 actttcaaca tctgtaacca aaaggtcaca aatgaaatat ttagtagaaa 950

 gtgcaatatc aatttattag gagtacctaa aattataact ctaaataata 1000

 tacagcaata ttattgctct attattacag caatcaataa tataatatag 1050

 ccactaggat acactcgctg tagaactcag aacaaaagat atcaatcttc 1100

 tgccagtccg catcattatg tgtagcagag actttactgg aatgagtgag 1150

 gggaaagata acaaaatgta gattaggatt ccacattctc ccctgcccat 1200

 cttcttgatt gctcagtttg aagacgatca ttgatggaca aatactttag 1250

 aaatgaatga agtcaatagc taatgtttct cccagaaact aaacaacata 1300

 gtttagggga tattaggcct acattctaat cacattgtaa ggaagtgatt 1350

 ttctaatttt gaagcttccc aggagcagcc ccctccagga acaattttcc 1400

 ctgtgaactt tcactgagaa actattatat gccatggagg agtcaaagat 1450

 gaattaagtc caatgctatc ctccaggagt gagctttgta gttggagaga 1500

 aaagccaacc ttatagatac aacctgtaca tatataacct atgctgcatt 1550

 taggcagatg ataagcccta ggaatggaaa gagggaaaag ctccctttcg 1600

 ccaggaatga tgaaggaaag ctttatggaa acacaggctg tatgtgaaag 1650

 atgggtgaat ctttgcaggt agggaagaag tagggggcat gtctggctga 1700

 gaaccggcct gatcatagag tggaaaaatg aaaggcagag gtgaaggaag 1750

 aatactaaat gtgaaaggct gaaatacaca gggaagtgtt gccagtgtgc 1800

 aacagaatct catctcgtgc aaaattgaat tagacttcct tactccttcc 1850

 ttactctggg taggtccatg tgcagccttt cctcagagca tctagcctga 1900

 catacttggc tcatctgctg tgcttctaag ccaaataaaa atcatcaaac 1950

 acatcgaaga tatttttggg agtcaccagg ttaaagcaaa gcctcagtca 2000

 ctgaaagcaa aaactgaatt ggccaggtct ccactgacaa aacagagtaa 2050

 atgatagtat gacagataat ttcaagtttt ccaagactcc aatttctgaa 2100

 aaatgtctca tgactccaaa aaatcacgta cttcctaaaa tgttgccagt 2150

 ggaggaccga atcaaggtta ttgctgacct cattttttca accttttcag 2200

 ttatttgacc tgaataggca atcccccagg atttctgatt gaattctacc 2250

 tgaaagttta gattttaaaa gacaacctgt aggaagctaa gtctcaggca 2300

 acaaaattta aaaccatcag aacttgtttc tccaaacatc aacctgctcc 2350

 tgtcaagtcc tttttcatct ctcccttttg tccctttaca tactgttttg 2400

 taagttcctt ttgatatcat ttattgcagg cagtattttt acatccatct 2450

 tcaagaaact tgggagacat ttagacattt agtatgtgta cttttagttg 2500

 tcttgcctct ttatttcaga taatgcctgt gattagtgaa tggcggcatt 2550

 attcctgaag acaaatgaag gaagataggg agcaagattg actgtcattt 2600

 gaatgatgga agagaagtag aattactgtg aggttacaaa aatcgtaagt 2650

 tagcagacat tgagaaagga aaacttccta cttgggcttt tcaggcttat 2700

 gtgacattat ctggatgtgt tttctagtct ttcctaaagg agaaattttt 2750

 attcctgggt tgctgaaagc tttctggact aaaaggatat aagcagctca 2800

 atagcagcat agaggattag attaatggaa cagcactgca tacaggaaag 2850

 ctacatctcc aatagtttag gctgcaagtc agtagccaaa cacaagagca 2900

 tgtaagattt ggaggacaaa gtataaatat tttaagttta cacaaccaag 2950

 attataggct accttcccaa cttctaattt gaagagcact gaaaatggag 3000

 ctgtgaacac ttcattttta aaacctgaca atatggtgct attgactact 3050

 taatacaaag atatattaca atatttttag gtaaatgtat taagtctggc 3100

 ctgggcataa atgtacatac agaaaatgtt tgtagagaat tcatcaaaat 3150

 catgcccatt tgctgttgta gagctacagt attcttcaat ggtggtgact 3200

 gaccagtgag tttctacttc ttacagatgg gacacaacag tcatgggctg 3250

 tctcagctgc ccaaagcctg aggcagacca catgagagct gtggcttctt 3300

 cttggattca ggttggataa cccaattcag taattaaata tgtaaatttt 3350

 ggggggggtt ggggggtgtt ttctaggaac ttgaagagta cgtgacatta 3400

 taaaaaatgg gtgttggaag actaattgta gaaatttgac ctgagggcca 3450

 atgttacttg gtgtaagttc actcagacag acatgtcaga acatgcccaa 3500

 agaagcctat atcttgctgc tgggaaatgt aaagcagttg gcatgtagaa 3550

 tacgataata aatcatttaa gaaaccacc 3579

<210> 4702
<211> 31
<212> PRT
<213> Homo sapien

<400> 4702
 Glu Thr Ile Trp Thr Ala Lys Pro Lys Ile Tyr Leu Asp Pro Tyr
   1               5                  10                  15

 Ser Lys Thr Met Thr Leu Gly Phe His Gly Thr Pro Met Pro Phe
                  20                  25                  30

 Trp


<210> 4703
<211> 1173
<212> DNA
<213> Homo sapien

<400> 4703
 ggcacgaggc agctcccttt gaaggcggat ccatacaaac aggctgacca 50

 tcagggctgg tcccaggcca ccaggctggg tgcaatgcag aaatggagat 100

 ctgccccggg gaaggcaggt ttctgcccaa acggagccac gtgaggacgt 150

 ctttggggat gtgtctccaa gaaaagtgtg ggctgccttc ctcaccctgg 200

 atgcctgtgg gctgccttcc tcaccctgga tgcctgtggg ctgccttcct 250

 caccctggat gcctgtgggc agccttcctc accctggatg cctgtgggct 300

 gccttcctca ccctggatgc ctgtgggctg ccttcctcac cctggatgcc 350

 tgtgggcagc cttcctcacc ctggatgcct gtgggctgcc ttcctcaccc 400

 tggatgcctg tgggcagcct tcctcaccct ggatgcctgt gggctgcctt 450

 cctcaccctg gatgcctgtg ggcagccttc ctcaccctgg atgcctgtgg 500

 gcagccttcc tcaccctgga tgcctgtgac ttggtttcca tgggggcttc 550

 ctaagctcag ggaccccaag cctccatcaa atctaatgac ccgccctgtc 600

 tctgaacaca cctgtgttgt ccccgagccc ctcaccaacc ccctctgcaa 650

 cccggcccac gcatttccca tcctgaaggg tccagctcat aggccggccc 700

 atgtgttccc tttacccctg ctttgtccct acctggtggg gagctgtccc 750

 ttctgggccc tagtgtggca cttcacacac aaatgtgtcc tgtgggtggt 800

 atctgggcct ccccctgcag tgaggggatg accaatgtgc agagctcact 850

 gggcctggat atgggctcgg gtggcacaga acagagagaa agtgctccgt 900

 aaaagtgagc tgcgatgcgg aggtgggcaa gctcttccct ggagggggaa 950

 gagctctcaa cccagaggga tctgaccagg aaggttcacc ccccctccac 1000

 ccaggaagcc cctgcagaca gtatgtgttt taggctttgc tggccaaatg 1050

 gtctctgccg tgactactca gctctgccat tgtggctgca gagtgaccat 1100

 agaccttctg aaagtgaatg agtatgactg tgttccaata aaactttatt 1150

 gacagaaaaa aaaaaaaaaa aaa 1173

<210> 4704
<211> 190
<212> PRT
<213> Homo sapien

<400> 4704
 Met Pro Val Gly Ser Leu Pro His Pro Gly Cys Leu Trp Ala Ala
   1               5                  10                  15

 Phe Leu Thr Leu Asp Ala Cys Gly Leu Pro Ser Ser Pro Trp Met
                  20                  25                  30

 Pro Val Gly Ser Leu Pro His Pro Gly Cys Leu Trp Ala Ala Phe
                  35                  40                  45

 Leu Thr Leu Asp Ala Cys Gly Gln Pro Ser Ser Pro Trp Met Pro
                  50                  55                  60

 Val Gly Cys Leu Pro His Pro Gly Cys Leu Trp Ala Ala Phe Leu
                  65                  70                  75

 Thr Leu Asp Ala Cys Gly Gln Pro Ser Ser Pro Trp Met Pro Val
                  80                  85                  90

 Thr Trp Phe Pro Trp Gly Leu Pro Lys Leu Arg Asp Pro Lys Pro
                  95                 100                 105

 Pro Ser Asn Leu Met Thr Arg Pro Val Ser Glu His Thr Cys Val
                 110                 115                 120

 Val Pro Glu Pro Leu Thr Asn Pro Leu Cys Asn Pro Ala His Ala
                 125                 130                 135

 Phe Pro Ile Leu Lys Gly Pro Ala His Arg Pro Ala His Val Phe
                 140                 145                 150

 Pro Leu Pro Leu Leu Cys Pro Tyr Leu Val Gly Ser Cys Pro Phe
                 155                 160                 165

 Trp Ala Leu Val Trp His Phe Thr His Lys Cys Val Leu Trp Val
                 170                 175                 180

 Val Ser Gly Pro Pro Pro Ala Val Arg Gly
                 185                 190

<210> 4705
<211> 2938
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1299-1507, 2016-2062
<223> Unknown base

<400> 4705
 cgggcgatca gaagcaggtc acacagcctg tttcctgttt tcaaacgggg 50

 aacttagaaa gtggcagccc ctcggcttgt tgccggagct gagaaccaag 100

 agctcgaagg ggccatatga cactcctccc ggacccctgg acacacacag 150

 ccctggagac tggagccttg gagcatggca agtccagagc accctgggag 200

 ccctggctgc atgggaccca taacccagtg cacggcaagg acccagcagg 250

 aagcaccagc cactggcccc gacctcccgc acccaggacc tgacgggcac 300

 ttagacacac acagtggcct gagctccaac tccagcatga ccacgcggga 350

 gcttcagcag tactggcaga accagaaatg ccgctggaag cacgtcaaac 400

 tgctctttga gatcgcttca gctcgcatcg aggagagaaa agtctctaag 450

 tttgtggtgt accaaatcat cgtcatccag actgggagct ttgacaacaa 500

 caaggccgtc ctggaacggc gctattccga cttcgcgaag ctccagaaag 550

 cgctgctgaa gacgttcagg gaggagatcg aagacgtgga gtttcccagg 600

 aagcacctga ctgggaactt cgctgaggag atgatctgtg agcgtcggcg 650

 cgccctgcag gagtacctgg gcctgctcta cgccatccgc tgcgtgcgcc 700

 gctcccggga gttcctggac ttcctcacgc ggccggagct gcgcgaggct 750

 ttcggctgcc tgcgggccgg ccagtacccg cgcgccctgg agctgctgct 800

 gcgcgtgctg ccgctgcagg agaagctcac cgcccactgc cctgcggccg 850

 ccgtcccggc cctgtgcgcc gtgctgctgt gccaccgcga cctcgaccgc 900

 cccgccgagg ccttcgcggc cggagagagg gccctgcagc gcctgcaggc 950

 ccgggagggc catcgctact atgcgcctct gctggacgcc atggtccgcc 1000

 tggcctacgc gctgggcaag gacttcgtga ctctgcagga gaggctggag 1050

 gagagccagc tccggaggcc cacgccccga ggcatcaccc tgaaggagct 1100

 cactgtgcga gaatacctgc actgagccgg cctgggaccc cgcagggacg 1150

 ctggagattt ggggtcacca tggctcacag tgggctgttt ggggttcttt 1200

 tttttatatt tattccttat actattattc agttattctg gaggacagtc 1250

 ttgcatctgt cacaccatga ctgaagtgca ggtggcgtca cattatgtnn 1300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1500

 nnnnnnncac acagtgtgag ccaccacccc tggcctgggg ttcattttta 1550

 atgggaaaag ccactggggg ctctaactcg ctgggtgact ttggacaagc 1600

 ccctcctctg gtcctcaatt tctccatctg tattggacag aggtgctcct 1650

 gggacccctt ggaagcctct gcttgtgtcc cacgtcctct tgatgccagg 1700

 gccacttcat ctccaaaaca caaaaccaac tgccaaaacc gtccagagca 1750

 gtgtccaccc caccagtgtc tttgtgggaa gctggagaag aagtttacct 1800

 cacacattct agacaaaact tagtccattt ccttgaagac agttctctcc 1850

 agctgctcca aggcttttct ctctgttcct tccaccttgg aattgcttta 1900

 aaatatttcc atccattatc ctaatactat cttagtattc tagcccttcc 1950

 cccttaccat gtagacctga caaagcaaaa caaaagctca cctattgccc 2000

 tcaagaacag cctctnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2050

 nnnnnnnnnn nncacggtgg gagttgtatg ccatcctttt gaagggtggg 2100

 aggaccctgg accagaaagc aataatggca taagattctg tgataccagg 2150

 catttttggc aagggaagtt gccaacaatt tttctggctg ggatggcata 2200

 gcacattgtc taggggtgga ttttcattca taaggcagct gttccctgaa 2250

 tggcttccct gggttatgta gaaacagcct ggggaggagg tgatacaaca 2300

 tacttaatgg ggcctctggg cagaaaacag actgaatcct caacactgcc 2350

 ccttttgagg gtctgtgatc ctggaacttc tctgatggac tgggatgccc 2400

 ttaactgagg tctgctgtct ggaaaggaca ccacaggccc agaatgaagg 2450

 ggcatctgga ccaatgacct agattcaaca cagggcttgg agctggtggt 2500

 acaggctggt tttggcccaa tgtgtgttgg aggctggaag cccctgaaga 2550

 cctaaactgc ctggatgagc ttattagggt gaattaatga gtctgtaatt 2600

 tgggaacctt aatgtgagac accacttaag gagaggaact tggcccagca 2650

 agtgatcact ctagaagtgg acagctatgc actagactgc accagaatct 2700

 gttcaacagc gacaccttgt ggtaaaaact gtagacgccc catcaggctg 2750

 gatgggaaac tagaaacaga ctgtctcatc tttggacaga tatccctcaa 2800

 atctcccaat ctactccagg gaaaagacac ttcaagtgag agatattgga 2850

 cttcttgaaa atctaggcct atggaaaatt aaagtgttaa atggaaaaat 2900

 taaagagcta tgagtctatt tgtaatgatg aaacagaa 2938

<210> 4706
<211> 262
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1299-1507, 2016-2062
<223> Unknown amino acid

<400> 4706
 Met Thr Thr Arg Glu Leu Gln Gln Tyr Trp Gln Asn Gln Lys Cys
   1               5                  10                  15

 Arg Trp Lys His Val Lys Leu Leu Phe Glu Ile Ala Ser Ala Arg
                  20                  25                  30

 Ile Glu Glu Arg Lys Val Ser Lys Phe Val Val Tyr Gln Ile Ile
                  35                  40                  45

 Val Ile Gln Thr Gly Ser Phe Asp Asn Asn Lys Ala Val Leu Glu
                  50                  55                  60

 Arg Arg Tyr Ser Asp Phe Ala Lys Leu Gln Lys Ala Leu Leu Lys
                  65                  70                  75

 Thr Phe Arg Glu Glu Ile Glu Asp Val Glu Phe Pro Arg Lys His
                  80                  85                  90

 Leu Thr Gly Asn Phe Ala Glu Glu Met Ile Cys Glu Arg Arg Arg
                  95                 100                 105

 Ala Leu Gln Glu Tyr Leu Gly Leu Leu Tyr Ala Ile Arg Cys Val
                 110                 115                 120

 Arg Arg Ser Arg Glu Phe Leu Asp Phe Leu Thr Arg Pro Glu Leu
                 125                 130                 135

 Arg Glu Ala Phe Gly Cys Leu Arg Ala Gly Gln Tyr Pro Arg Ala
                 140                 145                 150

 Leu Glu Leu Leu Leu Arg Val Leu Pro Leu Gln Glu Lys Leu Thr
                 155                 160                 165

 Ala His Cys Pro Ala Ala Ala Val Pro Ala Leu Cys Ala Val Leu
                 170                 175                 180

 Leu Cys His Arg Asp Leu Asp Arg Pro Ala Glu Ala Phe Ala Ala
                 185                 190                 195

 Gly Glu Arg Ala Leu Gln Arg Leu Gln Ala Arg Glu Gly His Arg
                 200                 205                 210

 Tyr Tyr Ala Pro Leu Leu Asp Ala Met Val Arg Leu Ala Tyr Ala
                 215                 220                 225

 Leu Gly Lys Asp Phe Val Thr Leu Gln Glu Arg Leu Glu Glu Ser
                 230                 235                 240

 Gln Leu Arg Arg Pro Thr Pro Arg Gly Ile Thr Leu Lys Glu Leu
                 245                 250                 255

 Thr Val Arg Glu Tyr Leu His
                 260

<210> 4707
<211> 2893
<212> DNA
<213> Homo sapien

<400> 4707
 taaaagcggc ccggggcggc cggcgcggcg cagaccctcg gtgggcagcg 50

 cactccagtc ttcccaggct agcggctgca gggagctccg gcccgcggcc 100

 cctccgcctc aagtctggga gctgccggtc ccactctgtc tttgcctatg 150

 gggattcgag agtttcccag cggcgcaccc aggggcaaga gcattgccgt 200

 tggcatgagg aggtcaccgg acgtcagccc ccggagactg tccgacatca 250

 gcccccagct ccggcagctc aagtacttgg tggtggacga ggcgattaag 300

 gaggatctga aatggtcgcg ctccgtggag gatctcacca gcgggccggt 350

 ggggctcacg tccatcgagg agcggatcct gcgcatcact ggctactatg 400

 gctaccagcc ctgggcagcg agctgcaaaa gggaggagcg cccccgggac 450

 tccccgggcc cggcggaggc ccaggcaccg gccggggtgg aggccggcgg 500

 gagagcgagt cgccgctgct ggacgtgctc ccgggcgcaa ctcaagaaga 550

 tcttctgggg cgtggcggtc gtgctgtgcg tgtgctcctc gtgggcgggc 600

 tccacgcagc tcgccaagct gaccttcagg aagttcgacg cgcccttcac 650

 cctcacgtgg tttgccacca actggaactt tttattcttc ccgttgtact 700

 acgtggggca cgtctgcaag tccacagaga agcagtctgt gaagcagcga 750

 tacagggaat gctgtcgatt ttttggagac aatggcttga ctttgaaggt 800

 gttttttacc aaggcagcac cctttggtgt tctttggaca ctcacaaact 850

 acctgtactt acatgcaata aagaaaataa acactacgga tgtctccgtg 900

 ttgttctgct gcaacaaagc ttttgtgttc ttgctctcat ggatcgttct 950

 cagggacaga ttcatgggag tgaggattgt ggccgccatc ctcgccatcg 1000

 ctggcattgt gatgatgacc tacgctgatg gcttccacag ccactccgtc 1050

 atcggcatcg cactggtggt ggcctcagca tcgatgtctg ccctctacaa 1100

 ggttttgttc aagctcctcc tgggcagtgc taagtttgga gaagccgcct 1150

 tatttttgtc catcttgggt gtgtttaaca tcctcttcat cacctgcatt 1200

 cctattatcc tctactttac caaagtggaa tactggagct cttttgatga 1250

 cattccatgg ggaaaccttt gtggattttc agttctttta ttgacattca 1300

 atattgtatt aaattttgga attgccgtta catatcccac tctgatgtct 1350

 cttggaatcg tcctcagcat acctgtgaat gcagtgattg atcactacac 1400

 cagtcagatc gtcttcaatg gggtccgggt catcgccatc atcatcatcg 1450

 gcctgggttt tctcctcctg ctcctgccag aggagtggga tgtctggttg 1500

 atcaagctgc tcacccgact caaagtgagg aagaaggagg agcctgcaga 1550

 gggcgctgcc gacctgagct caggacctca gagcaagaac agaagagccc 1600

 gcccttcctt cgcccgctaa caccactcct ctagaactcg gtggtaatga 1650

 ctgggaggtc tattcctgcc gggaggaacc tcagttgggt aaggtgtaca 1700

 tacctgtaca gttttggtca tctgcggtaa gttctatggt atttattggc 1750

 atgtccaatt tgcttgcact tttccacatc agaccttcca cttaagggta 1800

 ccaattcaat acaaaagaga aaagaagaac ctctcagtgc ttttccaacg 1850

 aatgtaaagt gggtttaaaa gttccctgcg tagatcgttt tggatggctg 1900

 acgttcttga caagccagcc atcagggcaa gtgttttgaa tcttagcaag 1950

 tgttttgaat cttagcaact gaacatgaca ttgcacactg tgattatttt 2000

 tcagctatgg taggtcatat tttgttttat accagagctg tactcttaat 2050

 tttaaggaat ttcaatgaac caaaagataa ctgtcaattt atttggatgg 2100

 atggatggag ggatggaagg agggagggaa ggatgtctgg gatgtgaaga 2150

 ggcaaggcag aaatggatga tgaacatcaa aaactgtcag aggacaggtc 2200

 tgtgccaggt accaggaagg acaagataag tccaagcccc ggctggcctg 2250

 ctctcacgtg tctgtgtaag atcatgcaag agaaatcaca gtgccttcta 2300

 cagaattttc gtctttacct atgtgaagcg aggtgacgtg atacgtcact 2350

 ggcgccgtct tataatttag atgtaaaaat ctttagaaac aaataaaact 2400

 ctctatatat gtgtatgtct gtgtacaaaa aaatgacaga gctgatggcc 2450

 agtgtataca gagcgtggcc cgcggtgtac aatacccata taaggtacat 2500

 tgtgcaggag gggaattgct ggctgctttt acttcctgac caagactgaa 2550

 aaattattta ctgaaatctg taaacctttt tatgaaactt ttaagcacca 2600

 ggctgtttac ttacacaatt taggtctgcc agaaaattct atctgtgata 2650

 gatctgtaaa gagggtcagg ggttagagtt tactattttt gaagtttaca 2700

 ttgttacata tgaaatggaa acattatttt gaaacgttgt cataacccaa 2750

 tggtgcattc tgtaaccatg gagtcttctg tttcctgggg gaaaggggca 2800

 ttcatgacct gaacttttta gcaaattatt attctcagtt tccattacct 2850

 gtttggccaa acagattaat aaaatatttg aaaaagaagc gtt 2893

<210> 4708
<211> 490
<212> PRT
<213> Homo sapien

<400> 4708
 Met Gly Ile Arg Glu Phe Pro Ser Gly Ala Pro Arg Gly Lys Ser
   1               5                  10                  15

 Ile Ala Val Gly Met Arg Arg Ser Pro Asp Val Ser Pro Arg Arg
                  20                  25                  30

 Leu Ser Asp Ile Ser Pro Gln Leu Arg Gln Leu Lys Tyr Leu Val
                  35                  40                  45

 Val Asp Glu Ala Ile Lys Glu Asp Leu Lys Trp Ser Arg Ser Val
                  50                  55                  60

 Glu Asp Leu Thr Ser Gly Pro Val Gly Leu Thr Ser Ile Glu Glu
                  65                  70                  75

 Arg Ile Leu Arg Ile Thr Gly Tyr Tyr Gly Tyr Gln Pro Trp Ala
                  80                  85                  90

 Ala Ser Cys Lys Arg Glu Glu Arg Pro Arg Asp Ser Pro Gly Pro
                  95                 100                 105

 Ala Glu Ala Gln Ala Pro Ala Gly Val Glu Ala Gly Gly Arg Ala
                 110                 115                 120

 Ser Arg Arg Cys Trp Thr Cys Ser Arg Ala Gln Leu Lys Lys Ile
                 125                 130                 135

 Phe Trp Gly Val Ala Val Val Leu Cys Val Cys Ser Ser Trp Ala
                 140                 145                 150

 Gly Ser Thr Gln Leu Ala Lys Leu Thr Phe Arg Lys Phe Asp Ala
                 155                 160                 165

 Pro Phe Thr Leu Thr Trp Phe Ala Thr Asn Trp Asn Phe Leu Phe
                 170                 175                 180

 Phe Pro Leu Tyr Tyr Val Gly His Val Cys Lys Ser Thr Glu Lys
                 185                 190                 195

 Gln Ser Val Lys Gln Arg Tyr Arg Glu Cys Cys Arg Phe Phe Gly
                 200                 205                 210

 Asp Asn Gly Leu Thr Leu Lys Val Phe Phe Thr Lys Ala Ala Pro
                 215                 220                 225

 Phe Gly Val Leu Trp Thr Leu Thr Asn Tyr Leu Tyr Leu His Ala
                 230                 235                 240

 Ile Lys Lys Ile Asn Thr Thr Asp Val Ser Val Leu Phe Cys Cys
                 245                 250                 255

 Asn Lys Ala Phe Val Phe Leu Leu Ser Trp Ile Val Leu Arg Asp
                 260                 265                 270

 Arg Phe Met Gly Val Arg Ile Val Ala Ala Ile Leu Ala Ile Ala
                 275                 280                 285

 Gly Ile Val Met Met Thr Tyr Ala Asp Gly Phe His Ser His Ser
                 290                 295                 300

 Val Ile Gly Ile Ala Leu Val Val Ala Ser Ala Ser Met Ser Ala
                 305                 310                 315

 Leu Tyr Lys Val Leu Phe Lys Leu Leu Leu Gly Ser Ala Lys Phe
                 320                 325                 330

 Gly Glu Ala Ala Leu Phe Leu Ser Ile Leu Gly Val Phe Asn Ile
                 335                 340                 345

 Leu Phe Ile Thr Cys Ile Pro Ile Ile Leu Tyr Phe Thr Lys Val
                 350                 355                 360

 Glu Tyr Trp Ser Ser Phe Asp Asp Ile Pro Trp Gly Asn Leu Cys
                 365                 370                 375

 Gly Phe Ser Val Leu Leu Leu Thr Phe Asn Ile Val Leu Asn Phe
                 380                 385                 390

 Gly Ile Ala Val Thr Tyr Pro Thr Leu Met Ser Leu Gly Ile Val
                 395                 400                 405

 Leu Ser Ile Pro Val Asn Ala Val Ile Asp His Tyr Thr Ser Gln
                 410                 415                 420

 Ile Val Phe Asn Gly Val Arg Val Ile Ala Ile Ile Ile Ile Gly
                 425                 430                 435

 Leu Gly Phe Leu Leu Leu Leu Leu Pro Glu Glu Trp Asp Val Trp
                 440                 445                 450

 Leu Ile Lys Leu Leu Thr Arg Leu Lys Val Arg Lys Lys Glu Glu
                 455                 460                 465

 Pro Ala Glu Gly Ala Ala Asp Leu Ser Ser Gly Pro Gln Ser Lys
                 470                 475                 480

 Asn Arg Arg Ala Arg Pro Ser Phe Ala Arg
                 485                 490

<210> 4709
<211> 1602
<212> DNA
<213> Homo sapien

<400> 4709
 gacttaggct gtgacccaca gaaggacgcc agaaagtact caagacattc 50

 acggtgcccc ggtcagcact cgccatgacg aagacttcta catgcatata 100

 ccacttcctt gttctgagct ggtatacttt cctcaattat tacatctcac 150

 aggaaggaaa agacgaggtg aaacccaaaa tcttggcaaa tggtgcaagg 200

 tggaaatata tgacgctgct taatctgctc ttgcagacca ttttctacgg 250

 ggtcacctgc ctggatgatg tgctgaaaag aaccaaaggg ggaaaagaca 300

 ttaagttcct aactgccttc agagacctgc ttttcaccac tctggctttt 350

 cctgtatcca cgtttgtatt tttggcattc tggatcctct ttctctacaa 400

 tcgagatctc atttacccca aggtcctaga tactgtcatc cccgtgtggc 450

 tgaatcatgc aatgcacact ttcatattcc ccatcacatt ggctgaagtc 500

 gtcctcaggc ctcactccta tccatcaaag aagacaggac tcaccttgct 550

 ggctgctgcc agcattgctt acatcagccg catcctatgg ctctactttg 600

 agacgggtac ctgggtgtat cctgtgtttg ccaaactcag cctcttgggt 650

 ctagcagctt tcttctctct cagctacgtc ttcatcgcca gcatctacct 700

 acttggagag aagctcaacc actggaaatg gggtgacatg aggcagccac 750

 ggaagaagag gaagtaattg cacaccattt tccaagaacc aagaaagaag 800

 aaaacacaag agatttttct catctttttt tttttttttt ctggtggagg 850

 gaggtggtgg aggaacatag caaagtagga gggacagaga gtgatactta 900

 aatttaataa gaggttcgtg aaggtagctt aacttgagaa ctcttggttt 950

 tttgaaaggt tgactgcaca tgccaaaaac aactcctgct atctcagaat 1000

 taattatctt tgaccttcgt ggaggatggt ctctggttaa aatctgacca 1050

 aagaaactca cataaacttg gtgttagaga acatctagag agagagagag 1100

 gaacttagag tcatttaaac tcttcagttt acagagaagg atgctgagga 1150

 cctagatgag aagttacctg caaaaggcaa aagggttact tagtgtcaga 1200

 accaaggcaa tgacttctct ctcccagatc tcctagctac tggtcctggg 1250

 ccattttttt ttttttaaat aatcccaact tttctttaaa agacaagcat 1300

 ttcagtaagc tagttatttt catgggttgc tcatccattt ttttcagtga 1350

 tctaaaaatg tagggagatg gctactactg aagttgtctg tctacttggg 1400

 ataatagcaa attaattgaa gacaatggga aagtaagtta taaaaaatac 1450

 tgggaaatct gtttctcttc tgagcaagca ttcagggcag gtataaacat 1500

 caaacatagt gacattgtca aaacctcttc catttgaaca ttgattaatt 1550

 catcaaataa atggtatagt aacaaaaaaa aaaaaaaaaa aaaaaaaaaa 1600

 aa 1602

<210> 4710
<211> 230
<212> PRT
<213> Homo sapien

<400> 4710
 Met Thr Lys Thr Ser Thr Cys Ile Tyr His Phe Leu Val Leu Ser
   1               5                  10                  15

 Trp Tyr Thr Phe Leu Asn Tyr Tyr Ile Ser Gln Glu Gly Lys Asp
                  20                  25                  30

 Glu Val Lys Pro Lys Ile Leu Ala Asn Gly Ala Arg Trp Lys Tyr
                  35                  40                  45

 Met Thr Leu Leu Asn Leu Leu Leu Gln Thr Ile Phe Tyr Gly Val
                  50                  55                  60

 Thr Cys Leu Asp Asp Val Leu Lys Arg Thr Lys Gly Gly Lys Asp
                  65                  70                  75

 Ile Lys Phe Leu Thr Ala Phe Arg Asp Leu Leu Phe Thr Thr Leu
                  80                  85                  90

 Ala Phe Pro Val Ser Thr Phe Val Phe Leu Ala Phe Trp Ile Leu
                  95                 100                 105

 Phe Leu Tyr Asn Arg Asp Leu Ile Tyr Pro Lys Val Leu Asp Thr
                 110                 115                 120

 Val Ile Pro Val Trp Leu Asn His Ala Met His Thr Phe Ile Phe
                 125                 130                 135

 Pro Ile Thr Leu Ala Glu Val Val Leu Arg Pro His Ser Tyr Pro
                 140                 145                 150

 Ser Lys Lys Thr Gly Leu Thr Leu Leu Ala Ala Ala Ser Ile Ala
                 155                 160                 165

 Tyr Ile Ser Arg Ile Leu Trp Leu Tyr Phe Glu Thr Gly Thr Trp
                 170                 175                 180

 Val Tyr Pro Val Phe Ala Lys Leu Ser Leu Leu Gly Leu Ala Ala
                 185                 190                 195

 Phe Phe Ser Leu Ser Tyr Val Phe Ile Ala Ser Ile Tyr Leu Leu
                 200                 205                 210

 Gly Glu Lys Leu Asn His Trp Lys Trp Gly Asp Met Arg Gln Pro
                 215                 220                 225

 Arg Lys Lys Arg Lys
                 230

<210> 4711
<211> 680
<212> DNA
<213> Homo sapien

<400> 4711
 atgggtgtat gttttcacat ctctcttaaa aacaattagt ctgacaaatc 50

 aaatcaaatc atttatgttt atttacgtag aacctcttgc aatcctgttt 100

 ggagagtgca acttacgatc ttagtttaat tgatcaatta ggagacctct 150

 gaataaagac taactcccca atacatccat aagaattttt ctatgagcct 200

 gtcatttaga tgtgataagc aatcaatttc atgaagactg tttcagtctt 250

 gtagaaattg agttgccatc acatagagga tttcttgtcc tctgcattgt 300

 ttaaaggaca actacaaatc atgctggata agagtactca ttcaatcttt 350

 taggattcaa tgaagtagca ttttaaatat gtaagttatt ttatatattg 400

 tctgtctttt aaaattggac tttgcttctt gaaaaaagtt tgtcaaatca 450

 ccaaaccata tgactgtcca ttcattgtag cctatgtttt ctattattaa 500

 gaaataattc atactgagag taaaagaaaa agaatgtatt ttgtgtgcaa 550

 aggatgaatg tattaaaaac tttttatttg taacaatttt ttaaaaaaac 600

 taaatggaaa ttgctttccc atgtacttgt atataaataa acatttcctg 650

 ttgcccacat ttggaaaaac aaataaaagg 680

<210> 4712
<211> 40
<212> PRT
<213> Homo sapien

<400> 4712
 Trp Val Tyr Val Phe Thr Ser Leu Leu Lys Thr Ile Ser Leu Thr
   1               5                  10                  15

 Asn Gln Ile Lys Ser Phe Met Phe Ile Tyr Val Glu Pro Leu Ala
                  20                  25                  30

 Ile Leu Phe Gly Glu Cys Asn Leu Arg Ser
                  35                  40

<210> 4713
<211> 2374
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2173-2204
<223> Unknown base

<400> 4713
 ccctgtctca aaaaaaataa aaaagtagaa agatggagtg gaagcctgcc 50

 cagggttgtg agcatgcacg ggaaaggcac ccaggtcagg ggggatcccc 100

 gaggagatgc ctgaggtgaa ggattgtggt tggggaaagc gtagtcccag 150

 caaggaagca gtttgtgggt aagtgctggg aggtgagtgg agtgagcttg 200

 tcagggagct gctggtggag cctggagggg aaggagggag gcagtgagag 250

 agatcggggt gggggttggg gggatgtcgc cagagctcag gggtggggac 300

 agccttgtgc gcatcagtcc tgaggcctgg ggcacctttc gtctgatgag 350

 cctctgcatg gagagaggct gagggctaaa cacagctgga tgtcacctga 400

 gttcatttat aggaagagag aaatgtcgag gtgaaacgta aaagcatctg 450

 gcaggaaggt gagtctgaag ccctgcaccc gcgttccgac tatcagtggg 500

 gagctgttag cacgtaggat tcttcagagc agctgggctg gagctcccct 550

 gagctcagga agccccaggg tgcaagggca aggaaatgag gggtggtggg 600

 tcagtgaaga tctgggcaga ccttgtgtgg ggaaggggtg ctgctgtgac 650

 ttcagggtct gaggtccaaa gacagcattt gaaaagaggc tctgaagcca 700

 gtgtttgaag aatttgttcc tgaagtacct cctgggggta ggctagaggc 750

 ttctggcttc agggtcctga agaacacatt gaggtgccgt ctgacactgg 800

 aatagggtgc ccttcattcc tatgcctgag tccttaacta tatttccaac 850

 ctccagtgag gaggagaaga ttcggaaatg tgacaggaga gcaaacagga 900

 cagtttgcat gtgtgtgtgc gcacacatac atgtgcgtga aagattatca 950

 ataaaagtgc ataaatttgt tgatctggta agagtttcta gcaggaaggt 1000

 cgagccactt actgtaggtc aagaagttgc tagttgcgga gttttttctt 1050

 gcagttagac tttacctagt ggtagcaggg ccaccaaagc tctgtgtccc 1100

 agatggtgta tggcccataa tccacccaac agcagcaaag gaccaggcaa 1150

 aggagaacag gagcagaagc ctcccagcca ctagcctttt gggctcagtc 1200

 tctccaataa tcctggagag gggcttcgtt gggtctggac acctaccatg 1250

 cattctgtga cctttcccta gcttccaata aataactgtt tgacgcccag 1300

 agtacaggat accacaatgc actcttcctg cgtagagcac atgttcccat 1350

 ctgctcccat tcctcaggaa ccttgaattc tagctctgct ggcctttgag 1400

 cccatgccag taaatgtcct gatgggcatt gcctactatc tccagggcag 1450

 ctgcctttgt cctcctaaca gctttattgg agtacagttc acttaccata 1500

 caatccacaa ttgaccctgc acaatttgat gccggtttag tatagtcaca 1550

 gttcagcagc catcagcaca gtcagtctta gagtttacta cccccaaaag 1600

 aaatccagcc ccccttagtc accaccccaa cctccccatc cctaggcacc 1650

 cctaggctac tttgatctct gtagacttgc ctcttctgga catgacatag 1700

 agaaaggagt cataaattct ccaaggtgtc tgtttcttct ttaatgtcat 1750

 tccctgtttc tcctcacatt ccctccccat ttcctgggcc cagtctcaca 1800

 ctggtccttg cttaccctaa atgctattaa ttccatcact ctgagtatgg 1850

 tgtttgctgt ccgctgaatg ccaagagctt caagagtgtg tgtaaataaa 1900

 gccacacctt tatttttgta ttattctgaa ccatggctaa taaattgttt 1950

 caccaagaaa tgtctctcta agaacagatg ccctccacgc tgtgcccctc 2000

 ccacctcttc agctcgtctc ctgagtgtgc agaggtggtt ccggttggga 2050

 aagaagcagc ggagcatcta accatgcctg tgtccaggcc gattatgcac 2100

 gcagccacca acaagctccc aactcccgcg tagagtttca tgactttttc 2150

 ctgcctacta tcttgatcct agnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2200

 nnnnttactt tgattcaaaa ccagtttctc ttttctgcat aggaaggtcc 2250

 ttgaaggtgt ttagggtcta aaaagggtgg tgttcggtct ctgaaacatc 2300

 cattcagcag tttgagctgg gatctctgaa tgcaagggta tgatggatat 2350

 acttctttct tgcttttgtt gtgt 2374

<210> 4714
<211> 37
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2173-2204
<223> Unknown amino acid

<400> 4714
 Pro Cys Leu Lys Lys Asn Lys Lys Val Glu Arg Trp Ser Gly Ser
   1               5                  10                  15

 Leu Pro Arg Val Val Ser Met His Gly Lys Gly Thr Gln Val Arg
                  20                  25                  30

 Gly Asp Pro Arg Gly Asp Ala
                  35

<210> 4715
<211> 5469
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 5034-5076
<223> Unknown base

<400> 4715
 gccgttcctg ccggcggttg gctaaaagac gttacagccg cgagacccga 50

 cacacaaaag ccgctttctc cgcgccgccc gcccagggag gctgcggcca 100

 gcaagggacc ccacctgaga gcagctcggg ctgctgagtt cgttttgtgt 150

 ctgagctctg cgctctgcac ggaaccgacc ccgtacccat ggctctgata 200

 atggaaccgg tgagcaaatg gtctccgagt caagtagtgg actggatgaa 250

 aggtcttgat gactgtttgc agcagtatat taagaacttt gagagggaga 300

 agatcagtgg ggaccagctg ctgcgcatta cacatcagga gctagaagat 350

 ctgggggtca gccgcattgg ccatcaggaa ctgatcttgg aagcagttga 400

 ccttctgtgt gcattgaatt atggcttgga aacagaaaat ctaaaaaccc 450

 tttctcacaa gttgaatgca tctgccaaaa atctgcagaa ttttataaca 500

 ggaaggagaa ggagtggcca ttatgatggg aggaccagcc gaaaattgcc 550

 aaacgacttt ctgacctcag ttgtggatct gattggagca gccaagagtc 600

 tgcttgcctg gttggacagg tcaccatttg ctgctgtgac agactattca 650

 gttacaagaa ataatgtcat acaactctgc ctggagttaa caacaattgt 700

 gcaacaggat tgtactgtat atgaaacaga gaataaaatt cttcacgtgt 750

 gtaaaactct ttctggagtc tgtgaccaca tcatatccct gtcgtcagat 800

 cctctggttt cacagtctgc tcacctggaa gtgattcaac tggcaaacat 850

 taaaccaagc gaagggctgg gtatgtatat taaatctaca tatgatggcc 900

 tccatgtaat tactggaacc acagaaaatt cacctgcaga tcggtgcaag 950

 aaaatccatg ctggcgatga agtgattcaa gttaatcatc agactgtggt 1000

 ggggtggcag ttgaaaaatt tggtgaatgc actacgagag gacccgagtg 1050

 gtgttatctt aactttgaaa aagcgacctc agagcatgct tacctcaggc 1100

 accagcttta ctgaaaaata tgagatggaa gccccttgct ctgcagcctc 1150

 ttatacctag aagtcccaca agcagcgttg ccacgccttc cagcaccatc 1200

 agtacaccca ccaaaagaga cagttctgcc ctccaggatc tctacattcc 1250

 ccctcctcct gcagaaccat atattcccag ggatgaaaaa ggaaaccttc 1300

 cttgtgaaga cctcagagga catatggtgg gcaagccagt gcataaggga 1350

 tctgaatcac caaattcatt tctggatcag gaatatcgaa agagatttaa 1400

 tattgtcgaa gaagatactg tcttatattg ctatgaatat gaaaaaggaa 1450

 gatcaagtag tcaaggaaga cgagaaagca ccccaactta tggcaagcta 1500

 cgacctatat ctatgccagt ggaatataat tgggtggggg actatgaaga 1550

 tccaaataag atgaagagag atagtagaag agaaaactct ctacttcggt 1600

 atatgagcaa tgaaaagatt gctcaagaag aatacatgtt tcagagaaac 1650

 agcaaaaagg acacagggaa gaagtcaaaa aagaagggtg ataagagtaa 1700

 tagcccaact cactattcat tgctacctag tttacaaatg gatgcactga 1750

 gacaagacat catgggcact cctgtgccag agaccacact ataccataca 1800

 tttcagcagt cctcactgca gcacaaatca aagaagaaaa acaaaggtcc 1850

 tatagcaggc aagagcaaaa gacgaatttc ttgcaaagat cttggccgtg 1900

 gtgactgtga gggctggctt tggaaaaaga aagatgcgaa gagttacttt 1950

 tcacagaaat ggaaaaaata ttggtttgtc ctaaaggatg catcccttta 2000

 ttggtatatt aatgaggagg atgaaaaagc agaaggattc attagcctgc 2050

 ctgaatttaa aattgataga gccagtgaat gccgcaaaaa atatgcattc 2100

 aaagcctgtc atcctaaaat caaaagcttt tattttgctg ctgaacatct 2150

 tgatgatatg aacaggtggc ttaacagaat taatatgctg actgcaggat 2200

 atgcagaaag agagaggatt aagcaggaac aagattactg gagtgagagt 2250

 gacaaggaag aagcagatac tccatcaaca ccaaaacaag atagccctcc 2300

 acccccatat gatacatacc cacgacctcc ctcgatgagt tgcgccagtc 2350

 cttatgtgga agcaaaacat agccgacttt cctccacgga gacttctcag 2400

 tctcagtctt ctcatgagga gtttcgccag gaagtaactg ggagcagtgc 2450

 agtgtctccc attcgcaaga cagccagtca gcgccgctcc tggcaggatt 2500

 taattgagac gccactgaca agttcaggct tacactatct tcagactctg 2550

 cccctggagg attctgtctt ctctgactcc gcggccatct ccccagagca 2600

 caggcggcag tctaccctgc caactcagaa atgccacctg caggatcact 2650

 atgggccata ccccttagct gagagtgaga ggatgcaagt gctaaatgga 2700

 aatgggggca agcctcgaag ttttactctg cctcgagata gcgggttcaa 2750

 ccattgctgt ctgaatgctc cagttagtgc ctgtgaccca caggatgacg 2800

 tgcaaccccc agaggtggag gaagaggagg aggaggagga ggaggaaggg 2850

 gaggcagcag gggaaaacat aggagaaaaa agtgaaagca gagaagaaaa 2900

 gttaggagac tcattgcaag atttatacag ggcactggag caggccagtc 2950

 tgtcaccact aggagaacat cgtatttcaa ccaagatgga atacaagcta 3000

 tcatttataa aaagatgtaa tgatcctgta atgaatgaaa aactacaccg 3050

 gctgagaatt ctcaaaagca ctttaaaggc cagagaaggg gaagtagcca 3100

 ttatcgataa agtcctagac aatccagact tgacatctaa agaattccaa 3150

 caatggaagc agatgtacct cgaccttttc ttggatatct gtcaaaatac 3200

 cacctcaaat gacccactga gtatttcttc tgaagtagat gtaatcactt 3250

 cctctctagc acacactcat tcatacattg aaacgcatgt ctaaatgtat 3300

 tctgccttca gaccatctag tacctgctgg tactctgaac aagtatataa 3350

 ggtagttttt atatcaatgt gtggaacact tgacaagcta tactttaatg 3400

 ttaccaaact atatgaaaca aaccatatat ggtcacaata ccactatctt 3450

 taatgagcat ttgtatattt tatatgcaac agtgctcagc ttatgtttac 3500

 catgtgcaaa atcaactgtc tttaatgact taaaattaac ttttgcaaac 3550

 aattctaaat acaggtggtc ttcaagtagt aaaaccacaa aaggcagttt 3600

 tctatctatg gtcatctttt ctccctttaa gttaatttta tataaacaag 3650

 acttcaaaag taaatcacat tttttcaggt gcagacatcc ttgtgggtgg 3700

 gaaagaattt aaaccttttt tatatttatt aaaatgttct aagaattttc 3750

 ttaaacattg cacaaagttt aatgctgtag ttttattttt gtgaaatgta 3800

 gatgcgcata caagagctaa gcaaaataga agagcatcga cataagaaaa 3850

 gttcaggtat ctaatattcg tcttaatagt ctattaactt gtgaaagcta 3900

 agttaatgga aatattattc caaatctatg agaacacttg gtgtatcagg 3950

 gcaaagcttt gtaagatgtt tttgtaacta agaccaaaat tgaagataga 4000

 gctgctttat tttcttggtt taaatcttcc tttatttttg tagtgatgag 4050

 atgctgattg tgtacagaag aatttgagag gggattttta aaaactgact 4100

 taacacaccc agaaaggcag ctaacagcta tatatatata taaatttcag 4150

 cccaaactca tgtttttaaa ctccaactct taaaagacaa caaggtataa 4200

 actgaaatga atcaactttc cacttagttt ccaattttcc cctagtccac 4250

 taattaaact taggtaatta tacttcaggt agggaagtac aatatgttta 4300

 gtttcaggct gatgtgtgtt ataaaaaaca acactgaaaa ataaaaatgt 4350

 acttcccttc taaggagcaa gcaggtgatg gtcattcaaa gagatgtcac 4400

 attgaattat gagagaaaca atttagaggt ttttttcctg gcttcatgaa 4450

 ttgttctata gagtggatga agtctaagga aaagtcctct tcatatattt 4500

 ccatttataa gcgtcttgtt tttgaaagtg atcacagcat gaaaatgact 4550

 gtgctgcttt ttagtgtctg gctgcataat gtacaagtca caatttgctg 4600

 tttttttcag gaggagaaag ggaacctcct ttactattct atatcctaaa 4650

 atctacttct aatcagcttt atactgttgc ctgtacagct cagtgaatgt 4700

 actttcatct ttaagagttc agatatatgc cagtgaatat ttttgctgta 4750

 gaggagaaag taaaaactcc acagcgggga tctttttctt tgcttttgaa 4800

 accaccattg aatcactatc gttttgcaga ctttgcacaa ctgtacagga 4850

 gagtggcctt tctacagcac attttcagta atcctatatt tagtcaaaat 4900

 ggatgagaaa tcatgtatta atgtttgtat ggaattttgg gtccagtgta 4950

 atatttttat catttaaaaa gaactctatt tgtaaaaaca tttatttact 5000

 gcatggatat tgacgcacat taaatttgtg ggannnnnnn nnnnnnnnnn 5050

 nnnnnnnnnn nnnnnnnnnn nnnnnncctc ttgtcctaaa atgaagtgtg 5100

 cttgttaaca ggtgtttaga cttattgatg tttactagac caaatgtgta 5150

 tgttcactta aaaatatatg tacctgatgg atgtgtcatg tttacagtgg 5200

 ccaggttgtg gcctgtaaac agcaagcagt tgacgggaag actagctctg 5250

 ttgctactaa gcagctttta cttttgtaaa gtcagctctg ttgttttaaa 5300

 tggtaaaaat taaactaatg aatttgacaa gactcgtggc tagcctagca 5350

 tgaaagagac cttttaacac tatataatat ctgtacattt tattgcattc 5400

 gtttcaaatc taggagagag gcagcactgt aaactgaagt caaataaatt 5450

 cagctcttaa tgaatcctt 5469

<210> 4716
<211> 1031
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 5034-5076
<223> Unknown amino acid

<400> 4716
 Met Glu Pro Val Ser Lys Trp Ser Pro Ser Gln Val Val Asp Trp
   1               5                  10                  15

 Met Lys Gly Leu Asp Asp Cys Leu Gln Gln Tyr Ile Lys Asn Phe
                  20                  25                  30

 Glu Arg Glu Lys Ile Ser Gly Asp Gln Leu Leu Arg Ile Thr His
                  35                  40                  45

 Gln Glu Leu Glu Asp Leu Gly Val Ser Arg Ile Gly His Gln Glu
                  50                  55                  60

 Leu Ile Leu Glu Ala Val Asp Leu Leu Cys Ala Leu Asn Tyr Gly
                  65                  70                  75

 Leu Glu Thr Glu Asn Leu Lys Thr Leu Ser His Lys Leu Asn Ala
                  80                  85                  90

 Ser Ala Lys Asn Leu Gln Asn Phe Ile Thr Gly Arg Arg Arg Ser
                  95                 100                 105

 Gly His Tyr Asp Gly Arg Thr Ser Arg Lys Leu Pro Asn Asp Phe
                 110                 115                 120

 Leu Thr Ser Val Val Asp Leu Ile Gly Ala Ala Lys Ser Leu Leu
                 125                 130                 135

 Ala Trp Leu Asp Arg Ser Pro Phe Ala Ala Val Thr Asp Tyr Ser
                 140                 145                 150

 Val Thr Arg Asn Asn Val Ile Gln Leu Cys Leu Glu Leu Thr Thr
                 155                 160                 165

 Ile Val Gln Gln Asp Cys Thr Val Tyr Glu Thr Glu Asn Lys Ile
                 170                 175                 180

 Leu His Val Cys Lys Thr Leu Ser Gly Val Cys Asp His Ile Ile
                 185                 190                 195

 Ser Leu Ser Ser Asp Pro Leu Val Ser Gln Ser Ala His Leu Glu
                 200                 205                 210

 Val Ile Gln Leu Ala Asn Ile Lys Pro Ser Glu Gly Leu Gly Met
                 215                 220                 225

 Tyr Ile Lys Ser Thr Tyr Asp Gly Leu His Val Ile Thr Gly Thr
                 230                 235                 240

 Thr Glu Asn Ser Pro Ala Asp Arg Cys Lys Lys Ile His Ala Gly
                 245                 250                 255

 Asp Glu Val Ile Gln Val Asn His Gln Thr Val Val Gly Trp Gln
                 260                 265                 270

 Leu Lys Asn Leu Val Asn Ala Leu Arg Glu Asp Pro Ser Gly Val
                 275                 280                 285

 Ile Leu Thr Leu Lys Lys Ser Asp Leu Arg Ala Cys Leu Pro Gln
                 290                 295                 300

 Ala Pro Ala Leu Leu Lys Asn Met Arg Trp Lys Pro Leu Ala Leu
                 305                 310                 315

 Gln Pro Leu Ile Pro Arg Ser Pro Thr Ser Ser Val Ala Thr Pro
                 320                 325                 330

 Ser Ser Thr Ile Ser Thr Pro Thr Lys Arg Asp Ser Ser Ala Leu
                 335                 340                 345

 Gln Asp Leu Tyr Ile Pro Pro Pro Pro Ala Glu Pro Tyr Ile Pro
                 350                 355                 360

 Arg Asp Glu Lys Gly Asn Leu Pro Cys Glu Asp Leu Arg Gly His
                 365                 370                 375

 Met Val Gly Lys Pro Val His Lys Gly Ser Glu Ser Pro Asn Ser
                 380                 385                 390

 Phe Leu Asp Gln Glu Tyr Arg Lys Arg Phe Asn Ile Val Glu Glu
                 395                 400                 405

 Asp Thr Val Leu Tyr Cys Tyr Glu Tyr Glu Lys Gly Arg Ser Ser
                 410                 415                 420

 Ser Gln Gly Arg Arg Glu Ser Thr Pro Thr Tyr Gly Lys Leu Arg
                 425                 430                 435

 Pro Ile Ser Met Pro Val Glu Tyr Asn Trp Val Gly Asp Tyr Glu
                 440                 445                 450

 Asp Pro Asn Lys Met Lys Arg Asp Ser Arg Arg Glu Asn Ser Leu
                 455                 460                 465

 Leu Arg Tyr Met Ser Asn Glu Lys Ile Ala Gln Glu Glu Tyr Met
                 470                 475                 480

 Phe Gln Arg Asn Ser Lys Lys Asp Thr Gly Lys Lys Ser Lys Lys
                 485                 490                 495

 Lys Gly Asp Lys Ser Asn Ser Pro Thr His Tyr Ser Leu Leu Pro
                 500                 505                 510

 Ser Leu Gln Met Asp Ala Leu Arg Gln Asp Ile Met Gly Thr Pro
                 515                 520                 525

 Val Pro Glu Thr Thr Leu Tyr His Thr Phe Gln Gln Ser Ser Leu
                 530                 535                 540

 Gln His Lys Ser Lys Lys Lys Asn Lys Gly Pro Ile Ala Gly Lys
                 545                 550                 555

 Ser Lys Arg Arg Ile Ser Cys Lys Asp Leu Gly Arg Gly Asp Cys
                 560                 565                 570

 Glu Gly Trp Leu Trp Lys Lys Lys Asp Ala Lys Ser Tyr Phe Ser
                 575                 580                 585

 Gln Lys Trp Lys Lys Tyr Trp Phe Val Leu Lys Asp Ala Ser Leu
                 590                 595                 600

 Tyr Trp Tyr Ile Asn Glu Glu Asp Glu Lys Ala Glu Gly Phe Ile
                 605                 610                 615

 Ser Leu Pro Glu Phe Lys Ile Asp Arg Ala Ser Glu Cys Arg Lys
                 620                 625                 630

 Lys Tyr Ala Phe Lys Ala Cys His Pro Lys Ile Lys Ser Phe Tyr
                 635                 640                 645

 Phe Ala Ala Glu His Leu Asp Asp Met Asn Arg Trp Leu Asn Arg
                 650                 655                 660

 Ile Asn Met Leu Thr Ala Gly Tyr Ala Glu Arg Glu Arg Ile Lys
                 665                 670                 675

 Gln Glu Gln Asp Tyr Trp Ser Glu Ser Asp Lys Glu Glu Ala Asp
                 680                 685                 690

 Thr Pro Ser Thr Pro Lys Gln Asp Ser Pro Pro Pro Pro Tyr Asp
                 695                 700                 705

 Thr Tyr Pro Arg Pro Pro Ser Met Ser Cys Ala Ser Pro Tyr Val
                 710                 715                 720

 Glu Ala Lys His Ser Arg Leu Ser Ser Thr Glu Thr Ser Gln Ser
                 725                 730                 735

 Gln Ser Ser His Glu Glu Phe Arg Gln Glu Val Thr Gly Ser Ser
                 740                 745                 750

 Ala Val Ser Pro Ile Arg Lys Thr Ala Ser Gln Arg Arg Ser Trp
                 755                 760                 765

 Gln Asp Leu Ile Glu Thr Pro Leu Thr Ser Ser Gly Leu His Tyr
                 770                 775                 780

 Leu Gln Thr Leu Pro Leu Glu Asp Ser Val Phe Ser Asp Ser Ala
                 785                 790                 795

 Ala Ile Ser Pro Glu His Arg Arg Gln Ser Thr Leu Pro Thr Gln
                 800                 805                 810

 Lys Cys His Leu Gln Asp His Tyr Gly Pro Tyr Pro Leu Ala Glu
                 815                 820                 825

 Ser Glu Arg Met Gln Val Leu Asn Gly Asn Gly Gly Lys Pro Arg
                 830                 835                 840

 Ser Phe Thr Leu Pro Arg Asp Ser Gly Phe Asn His Cys Cys Leu
                 845                 850                 855

 Asn Ala Pro Val Ser Ala Cys Asp Pro Gln Asp Asp Val Gln Pro
                 860                 865                 870

 Pro Glu Val Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Gly Glu
                 875                 880                 885

 Ala Ala Gly Glu Asn Ile Gly Glu Lys Ser Glu Ser Arg Glu Glu
                 890                 895                 900

 Lys Leu Gly Asp Ser Leu Gln Asp Leu Tyr Arg Ala Leu Glu Gln
                 905                 910                 915

 Ala Ser Leu Ser Pro Leu Gly Glu His Arg Ile Ser Thr Lys Met
                 920                 925                 930

 Glu Tyr Lys Leu Ser Phe Ile Lys Arg Cys Asn Asp Pro Val Met
                 935                 940                 945

 Asn Glu Lys Leu His Arg Leu Arg Ile Leu Lys Ser Thr Leu Lys
                 950                 955                 960

 Ala Arg Glu Gly Glu Val Ala Ile Ile Asp Lys Val Leu Asp Asn
                 965                 970                 975

 Pro Asp Leu Thr Ser Lys Glu Phe Gln Gln Trp Lys Gln Met Tyr
                 980                 985                 990

 Leu Asp Leu Phe Leu Asp Ile Cys Gln Asn Thr Thr Ser Asn Asp
                 995                1000                1005

 Pro Leu Ser Ile Ser Ser Glu Val Asp Val Ile Thr Ser Ser Leu
                1010                1015                1020

 Ala His Thr His Ser Tyr Ile Glu Thr His Val
                1025                1030

<210> 4717
<211> 11030
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 6512-6670, 8968, 8984
<223> Unknown base

<400> 4717
 gaggaatatg ggaccaaaat aaatgaaact ttcaggaaaa gatttaaaca 50

 acagagatct taaaaatagg aaattgaggt tgaagagaag atggcaaggc 100

 tagataataa gtcaaaaaca ttatttttaa agaaacaatt ttctttaaat 150

 aaatgacaga tactttttgt gtattacctg atatgataga ttgacagtat 200

 acatgtgaaa acagtttgga ttaataagtt cactttaccc atgagggtgg 250

 gaagtcaagg gaaagccagg ctcagctgct atttacatct ctgacctagg 300

 ctcttgtttg acctaagtct gtcttgatgc agcagcacaa gccagcgagg 350

 aggcagtgtc atttcgccgt gaacgcagca catttaggcg ccaggcagta 400

 cggcgccggc acaatgcagg gagtaaccct acccctccta cattgctcat 450

 cggatcaccc ctaagccttc aagatggtca gcaaggccag cagtccacag 500

 cccaggtcaa agtccagtcc cgcccccctt cccaggctgc agtgctcagt 550

 gctagtgcct ccttgctggt gagaaatggg agtgtccact tagaagcatc 600

 acatgacaat gcatctgctg taggcggtag cagtttgcac gatgaacttg 650

 gtaagttctc ttctacgctg tatgagactg gtggctgtga tatgtcactt 700

 gtgaattttg aaccagcagc aagaagagca tccaatatct gtgacacaga 750

 ttctcatgta tccagttcta cctcagttcg attttatcca catgatgtgc 800

 tctctctccc acagattcga ttgaatagac tattgaccat tgatacagat 850

 ttgttggagc aacaggacat tgatctaagc cctgacttgg cagctactta 900

 cggcccaaca gaagaagctg cccaaaaggt taaacactat tatcgctttt 950

 ggatcctacc ccagctgtgg attggcatta actttgacag actcacactt 1000

 ttggccctgt ttgatagaaa tcgtgagatc ctggaaaatg tgttagctgt 1050

 catcctggct attctcgtgg cctttttggg atctattctt ctcatacaag 1100

 gattcttcag agatatctgg gtcttccagt tctgcctcgt catagccagc 1150

 tgtcaatact cactgcttaa gagtgttcaa ccagattctt cttctcccag 1200

 acatggtcat aatcgtatca ttgcctacag tagaccagtt tatttctgca 1250

 tatgttgcgg tcttatttgg ctcttggatt atggtagcag aaacctgact 1300

 gcaaccaagt tcaaattata tggaataact ttcaccaatc cactggtgtt 1350

 tatatcagcc agggatttag ttatagtgtt tacactctgt ttcccaatag 1400

 tgtttttcat tggtctcctg cctcaggtga atacatttgt aatgtacctt 1450

 tgtgaacaat tggatattca tatttttggt ggtaatgcca ctacaagcct 1500

 gcttgcagca ctttacagtt ttatctgtag cattgttgca gtagccttat 1550

 tgtatggatt atgttatggg gctttaaagg attcttggga tggccagcat 1600

 attccagtac ttttctccat tttttgtggt ttattagtgg cagtgtctta 1650

 ccatctcagc cgacaaagca gtgatccatc tgtacttttc tctttagtgc 1700

 aatccaagat ttttccaaaa acggaagaga aaaatccaga agaccctcta 1750

 tctgaagtaa aagatccact gcctgaaaaa cttagaaatt ctgttagtga 1800

 gcgattacag tctgacctgg tagtatgcat tgtaattggt gtgctgtatt 1850

 ttgctattca tgtaagcaca gtcttcacag tattgcagcc tgccctcaag 1900

 tatgtgttgt atacattggt tggctttgtg ggttttggta acccattatg 1950

 tgctgcctca agttagaaaa cagctaccat ggcactgttt ctctcatcct 2000

 ctgctaaaga cactagagta taatcagtat gaagttcgaa atgcagccac 2050

 tatgatgtgg tttgagaaac ttcatgtgtg gcttcttttt gtggagaaga 2100

 atataatcta tccattgatt gttctcaatg aactgagcag cagtgcagag 2150

 acaattgcta gtccaaagaa actgaataca gaattaggtg ctttaatgat 2200

 cactgttgct ggtttgaagt tgctacgatc ctcttttagc agccctacat 2250

 atcagtatgt tacagtcatc tttactgtgc tgtttttcaa atttgactat 2300

 gaagcttttt cagagaccat gctgttggat ctcttcttta tgtccatact 2350

 cttcaacaag ctttgggaac tactttataa attgcagttt gtgtatacct 2400

 atattgcccc atggcagatc acatggggtt ctgctttcca tgcttttgct 2450

 cagccttttg cagtgcctca ttcagccatg ctgtttattc aggctgctgt 2500

 ctcggccttc ttctctactc cactgaaccc ctttctggga agtgcaatat 2550

 tcatcacttc atatgtccga cctgtgaaat tctgggagag agactataac 2600

 acaaaacgag tggatcattc aaataccaga ttggcttccc agcttgatag 2650

 aaatccagga tcagatgaca acaatctgaa ttccatcttt tatgagcatt 2700

 taactagatc cctacagcac agcctctgtg gtgatttgct actaggacgg 2750

 tggggaaact acagtacagg ggactgtttc atccttgcct ctgactatct 2800

 caatgcatta gtacacctta tagagatagg caatggtctg gtcacttttc 2850

 agctgcgggg acttgaattc agaggtacct actgtcaaca acgggaagtg 2900

 gaggccatta ctgaaggtgt agaggaagat gaaggatttt gctgttgtga 2950

 acctggccat attcctcaca tgctttcatt taatgctgca tttagccagc 3000

 gatggctagc ttgggaagtg atagtcacaa agtacattct ggagggttat 3050

 agcatcactg ataacagtgc tgcttctatg cttcaagtct ttgatcttcg 3100

 gaaagtactc accacttact atgtcaaggg tatcatttat tatgttacga 3150

 cctcgtctaa gctagaggag tggctagcta atgagacaat gcaggaagga 3200

 cttcgtctgt gtgctgatcg caattatgtc gatgtggacc cgacctttaa 3250

 tccaaacatt gatgaagact atgaccaccg actggcaggc atatctaggg 3300

 agagtttctg tgtgatttac ctcaactgga tagagtactg ctcttcccga 3350

 agagcaaagc ctgtggatgt ggacaaagat tcatccctag tgactctctg 3400

 ttatggactc tgtgttctgg gacggagagc tttggggact gcatcccatc 3450

 atatgtccag taatttagag tcattcctct atggattgca tgccctattt 3500

 aaaggagatt tccgtatttc ttcaattcga gatgaatgga tctttgctga 3550

 catggaattg ctaagaaaag tagtagtccc tgggatccgt atgtccatta 3600

 aacttcatca ggatcatttt acttctccag atgaatatga tgaccctact 3650

 gtgctctatg aagccatagt atctcatgag aagaacctcg taatagccca 3700

 tgaaggggac cctgcatggc ggagtgcagt acttgccaac tctccctcct 3750

 tgcttgctct gcggcatgtc atggatgatg gcaccaatga atataaaatc 3800

 atcatgctca acagacgcta cctgagcttc agggtcatta aagtgaataa 3850

 ggaatgtgtc cgaggtcttt gggcagggca acagcaggag cttgtttttc 3900

 tacgtaaccg taacccagag agaggtagca tccaaaatgc aaagcaagcc 3950

 ctgagaaaca tgataaactc atcttgtgat caacctattg gctacccaat 4000

 ctttgtctca cccctgacaa cttcttactc tgacagccac gaacagctta 4050

 aagacattct tgggggtcct atcagcttgg gaaatatcag gaacttcata 4100

 gtgtcaacct ggcacaggct taggaaaggt tgcggagctg gatgtaacag 4150

 tggtggcaat attgaagatt ctgatactgg aggtgggact tcctgcactg 4200

 gtaacaatgc aacaactgcc aacaatcccc acagcaacgt gacccaggga 4250

 agcattggaa atcctgggca gggatcagga actggactcc acccacctgt 4300

 cacatcttat cctccaacac taggcactag ccacagctct cactctgtgc 4350

 agtcgggcct ggtcagacag tctcctgccc gggcctcagt agccagccag 4400

 tcttcctact gctatagcag ccggcattca tccctccgga tgtccaccac 4450

 tgggtttgtg ccttgtcggc gctcttctac tagtcagata tcgcttcgaa 4500

 acttgccatc atccatccaa tcccgactgt cgatggtgaa ccaaatggaa 4550

 ccctcaggtc agagcggcct ggcctgtgtg cagcacggcc tgccttcctc 4600

 cagcagctcc agccaaagca tcccagcctg caaacatcac actctcgtgg 4650

 gctttcttgc gacagaggga ggtcagagca gtgccactga tgcacagcca 4700

 ggcaacacct taagtcctgc caacaattca cactccagaa aggcagaagt 4750

 gatttacaga gtccaaattg tggatcccag tcaaattctg gaagggatca 4800

 acctgtctaa aaggaaagag ctacagtggc ctgatgaagg aatccggtta 4850

 aaagctggga gaaatagctg gaaagactgg agtccgcagg agggcatgga 4900

 aggccatgtg attcaccgat gggtgccttg cagcagagat ccaggtacca 4950

 gatcccacat cgacaaggca gtgcttctgg tccagattga tgataaatat 5000

 gtgactgtaa ttgaaactgg ggtactagaa cttggggctg aagtgtgagc 5050

 cagtgtttat tataaagaca tttctttttc cctctcaatt ccaaggcatt 5100

 ggaaaaagag aggaacaagc agaagatgcc tgcaggtatc actttgatcc 5150

 tatgtgggag cgactgaaaa tagaatgagc ttggttaagc acctctcctt 5200

 tgcccttcac cctgactcct gtcactgtct ccatccccaa ataaagctga 5250

 aatatttttt taagttagct gccgagaaaa cattttgcat gaaggataaa 5300

 gttctgttaa aatacatcct taaaaaaagt ttttcctatg cattgcctat 5350

 gctttaaatc aacaaactct tcatttctaa actatgatct catatttttc 5400

 taatttcttt gccaaaaata attgccatgt tttgtcatag aacatgaaat 5450

 tcatttacct tgatttttaa gaacagacca gtgtagaaat gttccttttg 5500

 acttatagca gtataaaagt ttaatgtaca gtgaaagaga ctatgaacag 5550

 acatagattt atcttattcc ttgagcgcta aaaactttaa taaaaaaaac 5600

 tgcactaatt ttttacagca atgcactaaa gtctgagatt tctcagaaca 5650

 tttatttata tataaaaata aaataccatt atttaaattg ccttagggat 5700

 tagccccttc cctttcctta taaacacagg tagcaggaac tgtgctgctc 5750

 atttttctgt tagtagtgtg tacttcatgc caggacattg ggtattttct 5800

 ttaaagtgaa tatagaatct caagatatac gtagcttcat cattgacatt 5850

 tcccagagcc aatagtcagc ggatcggtct tgtgaacacc actgccagct 5900

 cctgtgtcta catctcagag gagcccatgt gctctgcttc tctccaccag 5950

 agcaagctct gctgggcgtg cttctgggaa gaaaacaatt ttctttaaga 6000

 agaagatgaa tgtccaggaa tttaaagaaa ggatcgattg ccttttattt 6050

 atgagtttct agctcttgaa gttattcaca tgcagttcag ttagtcaagt 6100

 aaaatttttt ttcaaataaa agtatccaag tggtgcagtt aattattata 6150

 tccctcttta ataattttgc tttttatttt tcccctcttc tttttctgtt 6200

 acttgaattt tatttcctgt aatttatagt gtgtagctgt aaattgaaat 6250

 atttataact gtgaaattga cttaattcat atgttgtctc ataactttat 6300

 tttttttaaa tgcatattca gggaaatata ttactcatat ttacaattgg 6350

 gcgatatagg aacttcaatt tagatttaat ttgcaactct tagcattttt 6400

 taaatccttg ataaaatttt cccttttggt gtgaaactcc aaagaaaatt 6450

 gtacatctcc tctgagcatt taggagcagc catctttcta ccccttgtga 6500

 ataaatcatt gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 6550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 6600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 6650

 nnnnnnnnnn nnnnnnnnnn tttgttgagg tgacagaaga gagaagctgt 6700

 ttttcctacc aattctgatg tagatctcac attatagcat aacattacag 6750

 tagaaggaat gaaaactaag aaagtaaata gtgaacatac agaacttact 6800

 gcatttccac tttaaaacct atttattttc cctttttcta attttaaact 6850

 tttgtggtca ttcagaacct aatgtgcctt gtgttgacat ttccatagac 6900

 ttcacacttt acaaaattta ctgtttaaaa atacttgtca aatgatttac 6950

 tgaaccttta tacaaaagta ccctttctaa attgaccatt taaaaatgta 7000

 tttttgtgat accgtcatta tgttctgcat ttgcctcatt ttggcagatc 7050

 tacagtatgc cattaaagtt tagtgttgtt tttggttttg gagggttttt 7100

 ttctgaaact gaatttataa tctatttctc tgtatacata tatttttaaa 7150

 atcttctgaa aggaactatg ttccctgctg cttcttccct ttctgaagtg 7200

 aatatgatct tttcatggtc attgcctaga taaaagtaga gccttttcaa 7250

 tcttagatgg aagataattc attttcccac acagaaaaaa aatctgacct 7300

 ttacatgatt taatctgaag ggctagaatt ttttaatttc tagcccctcc 7350

 tccaaaaaaa ttttaaacac atcacatact ctgaaaagtc agatttcaaa 7400

 tgcaagacta gactttatat ggaacatata tgttgggttt tgattttggg 7450

 tagcaattga catatatttt tctcaaaaca agttgaattt tgttaacata 7500

 tataattctt tagtgaattt ataaattagg acccctgaga agaagccctg 7550

 ttgtttttct taagagtcta aaactgacaa tcttttaaaa atcataatac 7600

 ttttctagta attgcatcag ggaattggtg ataattgaag aaagatccat 7650

 ttcttaagaa taatttgatc taaattatta tatggaaata aacatacttg 7700

 tgttaactaa attgatcata aattcttgtt cctgcctcac ccctcacccc 7750

 ccagagaata gtgagtgact cgtttagatt ctctgctttt tttcagttat 7800

 gtacaagact tcagcataca ttaatgtctt tagtttataa atttgccaat 7850

 gctttaattt ccataatttg aaagttaaaa gatgtaacta aaatactagc 7900

 ttttttattc atttcctttt ggtggagttg tatgattgaa aactttgctt 7950

 tttcttgttt aattcttccg ccaccccctc ttttgagaga aaggtaatcg 8000

 tggaatgagt tataaattat tgcctgtttt tcctttattt ctttcattca 8050

 gtggcaaaaa acattttata actcctaagt ttttggttaa tcttccaact 8100

 tataccttgg tgtgaactct ctttttacac cattttcaac actggataaa 8150

 actttaatgt tgactttttg ctaaagaact ttaatttttc caagaatcta 8200

 gattaacata agatgttgat atttaaggaa cttggaagag taagtggtga 8250

 ggctgtatgt atatttttta agagattacc ttttaggaaa ttagtgaaca 8300

 aacttaacca gtgttctgcc ttctttgact ttgttactgg aggatgataa 8350

 tctatttcta ttagattcga agtattttgg aaaatatttc aagtatatct 8400

 gaactactta taattcttaa aacagaagta gtcagacaat atttgtatcc 8450

 taagtgagat atggaaaatt actctgtata ctaaatgtca ggcaatgaaa 8500

 atgtaagttt ttgtgtagaa aacccattaa gaagatgtgt ttttctttct 8550

 gaattagttt atttttccat cacataccaa aatataaaaa tcagcctcac 8600

 atttttcagc aagtttagct tatagccttg ataaattcct ctgtgcttct 8650

 gagcagcatc cttctgcctc tgcttagcag ctctgcattt ggtggattgc 8700

 tgttgtgagt cattcatcca gcactgggcc ttttaagctg aagattcacc 8750

 cagtgtctaa agttgtcctt ttcttatagc tagctttcaa gcatctttcc 8800

 tcctaaataa atatgtgact tgagaaaaag gtaataatga ttttgtcaga 8850

 attctttgaa tttatattta ctagctactt aaccataaac tgctgtccag 8900

 attgttaatt tcatttatat ttattttaat taatttgtca tgaatatgga 8950

 caaagccttt tctggggngt gtgtgtgtgt atanagtttg ttggttaagt 9000

 cgtcattatt cattcgtatt ctttttctgt gtaatgtaat catataaagt 9050

 tactttggac agagacccag ttaattttct cttttgatag gatacatggt 9100

 ttagataagg tataaagtgt ccctttttat tctagaggct tttcctttaa 9150

 ttcagagatt agtggagata ataacatcag tcaaggctaa tgtggtacat 9200

 ggaacttgct aatggaggtt ggacattctg tttcagtctt acatggatat 9250

 tgtttcattg gtgttgagga agaaaaaaat tagatactac catgcattgg 9300

 gacagcataa ttctaatatt acattgaata tggcttttta aaaataagta 9350

 ttaaaaagcc aatcgttttc tccatttatc tatctttttt gtttgttttt 9400

 aatttggttg attgatatgc acccaggccg tcttattttt acttgttaaa 9450

 tgtctgtcta ggaagaactg tgattggaaa ggaattaatt attatacaaa 9500

 taaatctggt aggatatgag tggagtaagt ttgcttgaaa cagaagtata 9550

 ttttctactt tgaatcacct caccagagtc atctgtcaag aattatgtat 9600

 aacaatttat ctttattgcc tacatacaac atactttttc tgaattaaga 9650

 taacttctat ttgtgagttg aacttcatta tctgccattt tgtggaatca 9700

 accttacatt ctttggtgga actagagctg attgtcacca caaggttata 9750

 tgacaactct gttctaagac ttatacctat tatatagggt tatacctttt 9800

 ttcttatgcc tcagctctgt acctgacaat ttatgattca gtggagccaa 9850

 gctagaagga acaaaggtca tctaacactg tgatggggat gaattcctga 9900

 gttttacctg cacaatgagg tggtgccccg gaattcacaa cagagtagtg 9950

 atagagcata agatggctgc tccagatgac tcttgggttt agtgtacttg 10000

 tgattgaaca agatttttta tctatgaagc ttgattctac aaccaaaata 10050

 atagaaatgg gggggggggg ggaatcatgt ctgcttatgc tttttaaaag 10100

 cttatagttt aagtaaaagt aaaatgtaaa aactgattaa acctatacaa 10150

 gtctggcaat gagctctgca tgaggaaatg gaaggaggaa tattgaaaat 10200

 gattctagga aagtgaacgt aagaaaggaa aatgggtttt ccttttctga 10250

 tcatgggctc tggaaagtat tcatggcctt taccagcatt cagtataaac 10300

 cagagataag gacatatgta cttacgtgtg tctgtgagtg tgtgtgtgtc 10350

 tgagtgttat tctgaacagc ttgtaaatat tgtagttgtt taaaatggaa 10400

 aataaaagct gagttctttt ggcaaatata ttgcatcaaa aatacagtat 10450

 tgacagtgga taaaacactg aggaaataaa ttttttttca ttttgccttc 10500

 tgtccatttt ttgtcaaact gagaaaaatt agagtacact atattaagtt 10550

 ctgtatggca tgttcacact tggttctgaa atcattttaa acaagctttg 10600

 gcctgtaaac atgagcttca acttgcaata gatcaaaagc gtacatcata 10650

 cttcatgtta aaacatggtc tgtttcacac ttttcttagt gcaagggttg 10700

 tagtttgtct tctgaattta tctcgatgtt acatattaac aatattagat 10750

 agaacatgta ggataaaaat gtgtgttcaa tcacagacta aactacaata 10800

 cagaaaatgg aaagaacatt tggattatgg tcatcaaagg caggtacaaa 10850

 cttgtttggt atatttgcag tgtgtactaa ctcagtgatt tcacatataa 10900

 tacagaaaat gcaagctaat ttacaatgag aatagacata ttcttgatta 10950

 aatcacttat aatcctttaa tgcatcattt taactattta ttagtaagaa 11000

 ccagaaccag cacgatacag attatatgcc 11030

<210> 4718
<211> 1451
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 6512-6670, 8968, 8984
<223> Unknown amino acid

<400> 4718
 Met Ser Leu Val Asn Phe Glu Pro Ala Ala Arg Arg Ala Ser Asn
   1               5                  10                  15

 Ile Cys Asp Thr Asp Ser His Val Ser Ser Ser Thr Ser Val Arg
                  20                  25                  30

 Phe Tyr Pro His Asp Val Leu Ser Leu Pro Gln Ile Arg Leu Asn
                  35                  40                  45

 Arg Leu Leu Thr Ile Asp Thr Asp Leu Leu Glu Gln Gln Asp Ile
                  50                  55                  60

 Asp Leu Ser Pro Asp Leu Ala Ala Thr Tyr Gly Pro Thr Glu Glu
                  65                  70                  75

 Ala Ala Gln Lys Val Lys His Tyr Tyr Arg Phe Trp Ile Leu Pro
                  80                  85                  90

 Gln Leu Trp Ile Gly Ile Asn Phe Asp Arg Leu Thr Leu Leu Ala
                  95                 100                 105

 Leu Phe Asp Arg Asn Arg Glu Ile Leu Glu Asn Val Leu Ala Val
                 110                 115                 120

 Ile Leu Ala Ile Leu Val Ala Phe Leu Gly Ser Ile Leu Leu Ile
                 125                 130                 135

 Gln Gly Phe Phe Arg Asp Ile Trp Val Phe Gln Phe Cys Leu Val
                 140                 145                 150

 Ile Ala Ser Cys Gln Tyr Ser Leu Leu Lys Ser Val Gln Pro Asp
                 155                 160                 165

 Ser Ser Ser Pro Arg His Gly His Asn Arg Ile Ile Ala Tyr Ser
                 170                 175                 180

 Arg Pro Val Tyr Phe Cys Ile Cys Cys Gly Leu Ile Trp Leu Leu
                 185                 190                 195

 Asp Tyr Gly Ser Arg Asn Leu Thr Ala Thr Lys Phe Lys Leu Tyr
                 200                 205                 210

 Gly Ile Thr Phe Thr Asn Pro Leu Val Phe Ile Ser Ala Arg Asp
                 215                 220                 225

 Leu Val Ile Val Phe Thr Leu Cys Phe Pro Ile Val Phe Phe Ile
                 230                 235                 240

 Gly Leu Leu Pro Gln Val Asn Thr Phe Val Met Tyr Leu Cys Glu
                 245                 250                 255

 Gln Leu Asp Ile His Ile Phe Gly Gly Asn Ala Thr Thr Ser Leu
                 260                 265                 270

 Leu Ala Ala Leu Tyr Ser Phe Ile Cys Ser Ile Val Ala Val Ala
                 275                 280                 285

 Leu Leu Tyr Gly Leu Cys Tyr Gly Ala Leu Lys Asp Ser Trp Asp
                 290                 295                 300

 Gly Gln His Ile Pro Val Leu Phe Ser Ile Phe Cys Gly Leu Leu
                 305                 310                 315

 Val Ala Val Ser Tyr His Leu Ser Arg Gln Ser Ser Asp Pro Ser
                 320                 325                 330

 Val Leu Phe Ser Leu Val Gln Ser Lys Ile Phe Pro Lys Thr Glu
                 335                 340                 345

 Glu Lys Asn Pro Glu Asp Pro Leu Ser Glu Val Lys Asp Pro Leu
                 350                 355                 360

 Pro Glu Lys Leu Arg Asn Ser Val Ser Glu Arg Leu Gln Ser Asp
                 365                 370                 375

 Leu Val Val Cys Ile Val Ile Gly Val Leu Tyr Phe Ala Ile His
                 380                 385                 390

 Val Ser Thr Val Phe Thr Val Leu Gln Pro Ala Leu Lys Tyr Val
                 395                 400                 405

 Leu Tyr Thr Leu Val Gly Phe Val Gly Phe Gly Asn Pro Leu Cys
                 410                 415                 420

 Ala Ala Ser Ser Arg Lys Gln Leu Pro Trp His Cys Phe Ser His
                 425                 430                 435

 Pro Leu Leu Lys Thr Leu Glu Tyr Asn Gln Tyr Glu Val Arg Asn
                 440                 445                 450

 Ala Ala Thr Met Met Trp Phe Glu Lys Leu His Val Trp Leu Leu
                 455                 460                 465

 Phe Val Glu Lys Asn Ile Ile Tyr Pro Leu Ile Val Leu Asn Glu
                 470                 475                 480

 Leu Ser Ser Ser Ala Glu Thr Ile Ala Ser Pro Lys Lys Leu Asn
                 485                 490                 495

 Thr Glu Leu Gly Ala Leu Met Ile Thr Val Ala Gly Leu Lys Leu
                 500                 505                 510

 Leu Arg Ser Ser Phe Ser Ser Pro Thr Tyr Gln Tyr Val Thr Val
                 515                 520                 525

 Ile Phe Thr Val Leu Phe Phe Lys Phe Asp Tyr Glu Ala Phe Ser
                 530                 535                 540

 Glu Thr Met Leu Leu Asp Leu Phe Phe Met Ser Ile Leu Phe Asn
                 545                 550                 555

 Lys Leu Trp Glu Leu Leu Tyr Lys Leu Gln Phe Val Tyr Thr Tyr
                 560                 565                 570

 Ile Ala Pro Trp Gln Ile Thr Trp Gly Ser Ala Phe His Ala Phe
                 575                 580                 585

 Ala Gln Pro Phe Ala Val Pro His Ser Ala Met Leu Phe Ile Gln
                 590                 595                 600

 Ala Ala Val Ser Ala Phe Phe Ser Thr Pro Leu Asn Pro Phe Leu
                 605                 610                 615

 Gly Ser Ala Ile Phe Ile Thr Ser Tyr Val Arg Pro Val Lys Phe
                 620                 625                 630

 Trp Glu Arg Asp Tyr Asn Thr Lys Arg Val Asp His Ser Asn Thr
                 635                 640                 645

 Arg Leu Ala Ser Gln Leu Asp Arg Asn Pro Gly Ser Asp Asp Asn
                 650                 655                 660

 Asn Leu Asn Ser Ile Phe Tyr Glu His Leu Thr Arg Ser Leu Gln
                 665                 670                 675

 His Ser Leu Cys Gly Asp Leu Leu Leu Gly Arg Trp Gly Asn Tyr
                 680                 685                 690

 Ser Thr Gly Asp Cys Phe Ile Leu Ala Ser Asp Tyr Leu Asn Ala
                 695                 700                 705

 Leu Val His Leu Ile Glu Ile Gly Asn Gly Leu Val Thr Phe Gln
                 710                 715                 720

 Leu Arg Gly Leu Glu Phe Arg Gly Thr Tyr Cys Gln Gln Arg Glu
                 725                 730                 735

 Val Glu Ala Ile Thr Glu Gly Val Glu Glu Asp Glu Gly Phe Cys
                 740                 745                 750

 Cys Cys Glu Pro Gly His Ile Pro His Met Leu Ser Phe Asn Ala
                 755                 760                 765

 Ala Phe Ser Gln Arg Trp Leu Ala Trp Glu Val Ile Val Thr Lys
                 770                 775                 780

 Tyr Ile Leu Glu Gly Tyr Ser Ile Thr Asp Asn Ser Ala Ala Ser
                 785                 790                 795

 Met Leu Gln Val Phe Asp Leu Arg Lys Val Leu Thr Thr Tyr Tyr
                 800                 805                 810

 Val Lys Gly Ile Ile Tyr Tyr Val Thr Thr Ser Ser Lys Leu Glu
                 815                 820                 825

 Glu Trp Leu Ala Asn Glu Thr Met Gln Glu Gly Leu Arg Leu Cys
                 830                 835                 840

 Ala Asp Arg Asn Tyr Val Asp Val Asp Pro Thr Phe Asn Pro Asn
                 845                 850                 855

 Ile Asp Glu Asp Tyr Asp His Arg Leu Ala Gly Ile Ser Arg Glu
                 860                 865                 870

 Ser Phe Cys Val Ile Tyr Leu Asn Trp Ile Glu Tyr Cys Ser Ser
                 875                 880                 885

 Arg Arg Ala Lys Pro Val Asp Val Asp Lys Asp Ser Ser Leu Val
                 890                 895                 900

 Thr Leu Cys Tyr Gly Leu Cys Val Leu Gly Arg Arg Ala Leu Gly
                 905                 910                 915

 Thr Ala Ser His His Met Ser Ser Asn Leu Glu Ser Phe Leu Tyr
                 920                 925                 930

 Gly Leu His Ala Leu Phe Lys Gly Asp Phe Arg Ile Ser Ser Ile
                 935                 940                 945

 Arg Asp Glu Trp Ile Phe Ala Asp Met Glu Leu Leu Arg Lys Val
                 950                 955                 960

 Val Val Pro Gly Ile Arg Met Ser Ile Lys Leu His Gln Asp His
                 965                 970                 975

 Phe Thr Ser Pro Asp Glu Tyr Asp Asp Pro Thr Val Leu Tyr Glu
                 980                 985                 990

 Ala Ile Val Ser His Glu Lys Asn Leu Val Ile Ala His Glu Gly
                 995                1000                1005

 Asp Pro Ala Trp Arg Ser Ala Val Leu Ala Asn Ser Pro Ser Leu
                1010                1015                1020

 Leu Ala Leu Arg His Val Met Asp Asp Gly Thr Asn Glu Tyr Lys
                1025                1030                1035

 Ile Ile Met Leu Asn Arg Arg Tyr Leu Ser Phe Arg Val Ile Lys
                1040                1045                1050

 Val Asn Lys Glu Cys Val Arg Gly Leu Trp Ala Gly Gln Gln Gln
                1055                1060                1065

 Glu Leu Val Phe Leu Arg Asn Arg Asn Pro Glu Arg Gly Ser Ile
                1070                1075                1080

 Gln Asn Ala Lys Gln Ala Leu Arg Asn Met Ile Asn Ser Ser Cys
                1085                1090                1095

 Asp Gln Pro Ile Gly Tyr Pro Ile Phe Val Ser Pro Leu Thr Thr
                1100                1105                1110

 Ser Tyr Ser Asp Ser His Glu Gln Leu Lys Asp Ile Leu Gly Gly
                1115                1120                1125

 Pro Ile Ser Leu Gly Asn Ile Arg Asn Phe Ile Val Ser Thr Trp
                1130                1135                1140

 His Arg Leu Arg Lys Gly Cys Gly Ala Gly Cys Asn Ser Gly Gly
                1145                1150                1155

 Asn Ile Glu Asp Ser Asp Thr Gly Gly Gly Thr Ser Cys Thr Gly
                1160                1165                1170

 Asn Asn Ala Thr Thr Ala Asn Asn Pro His Ser Asn Val Thr Gln
                1175                1180                1185

 Gly Ser Ile Gly Asn Pro Gly Gln Gly Ser Gly Thr Gly Leu His
                1190                1195                1200

 Pro Pro Val Thr Ser Tyr Pro Pro Thr Leu Gly Thr Ser His Ser
                1205                1210                1215

 Ser His Ser Val Gln Ser Gly Leu Val Arg Gln Ser Pro Ala Arg
                1220                1225                1230

 Ala Ser Val Ala Ser Gln Ser Ser Tyr Cys Tyr Ser Ser Arg His
                1235                1240                1245

 Ser Ser Leu Arg Met Ser Thr Thr Gly Phe Val Pro Cys Arg Arg
                1250                1255                1260

 Ser Ser Thr Ser Gln Ile Ser Leu Arg Asn Leu Pro Ser Ser Ile
                1265                1270                1275

 Gln Ser Arg Leu Ser Met Val Asn Gln Met Glu Pro Ser Gly Gln
                1280                1285                1290

 Ser Gly Leu Ala Cys Val Gln His Gly Leu Pro Ser Ser Ser Ser
                1295                1300                1305

 Ser Ser Gln Ser Ile Pro Ala Cys Lys His His Thr Leu Val Gly
                1310                1315                1320

 Phe Leu Ala Thr Glu Gly Gly Gln Ser Ser Ala Thr Asp Ala Gln
                1325                1330                1335

 Pro Gly Asn Thr Leu Ser Pro Ala Asn Asn Ser His Ser Arg Lys
                1340                1345                1350

 Ala Glu Val Ile Tyr Arg Val Gln Ile Val Asp Pro Ser Gln Ile
                1355                1360                1365

 Leu Glu Gly Ile Asn Leu Ser Lys Arg Lys Glu Leu Gln Trp Pro
                1370                1375                1380

 Asp Glu Gly Ile Arg Leu Lys Ala Gly Arg Asn Ser Trp Lys Asp
                1385                1390                1395

 Trp Ser Pro Gln Glu Gly Met Glu Gly His Val Ile His Arg Trp
                1400                1405                1410

 Val Pro Cys Ser Arg Asp Pro Gly Thr Arg Ser His Ile Asp Lys
                1415                1420                1425

 Ala Val Leu Leu Val Gln Ile Asp Asp Lys Tyr Val Thr Val Ile
                1430                1435                1440

 Glu Thr Gly Val Leu Glu Leu Gly Ala Glu Val
                1445                1450

<210> 4719
<211> 2158
<212> DNA
<213> Homo sapien

<400> 4719
 agaagatgta cttacaatgc agtgggtggt tttaactcta taacctttgg 50

 gctctgtggt tggtgctccc cttcctaaat aaatgaggtg tatgcagggc 100

 cctcttctgc cttagcgccc tgccagctgg gactccagca aggcccgggg 150

 cacctgagga cagagtgaga tggagggccg ctgctccagc agccgggcct 200

 gcatcccaca agtcaactgt gtcggacaga ggatccttac aaagaagagg 250

 cagcagggtt gggggctggc cagctgctcg tccgccctag gtagcttgct 300

 catctgtaaa gtgggtgggg caggagttcc cacctcatgg ggtcctggca 350

 agcctgcagt atccccgagt ggcaccagcc tgcttctggg gcagagcagt 400

 ttgtgccccc tgaggtacca ctgatcctct ttccctgcta ttaggtattg 450

 ctctctccct ccggtgtttg ccttttcaga ttataaaagt aatatgtgtt 500

 cccatatttg gcgtctctca ggagctcagg aagtacttgg ctgagtggac 550

 atgtccattg tggaaaaatg gcaacaatat ggattccatg ggtatatttt 600

 atagaagaat atgaagaaaa gcagctaccc ctaaacccat ggcacaagct 650

 gttcatgtta attctgtacc cgacgctttc cccacggggc ctcccctcac 700

 tctgaaatgg catccaggtc catcttgccc tccacctctg catggctctc 750

 catgccccat cgcctctccc agatcctagc actgggtcca cactctcgcc 800

 ctgtccattt aggttgatga aagcaggcag tcacccgggt gggccagtct 850

 tgcctgtggg aggaacatgc agtctcctgt ctcatggttt gaagtgtgcc 900

 aggaagcctg gcccagccca cctccccctg gagtccttcc caggaggaat 950

 aaccccttag gtcattgact ataagatgag ttcgctcact ggatccttcc 1000

 tctctgatga gacaggaaga aggtacacag tgaccaggta ggaggaggag 1050

 agggagtaga aaggagggat gcgggtggct ggtccctgca tttgcctgct 1100

 tccctgcacg ggtgtcccac tggccgcctc tgctcaccag tgtcatggga 1150

 ttctctcaga agatgaaaac agcccctgct tttttgctag aatggctgag 1200

 ctttcatgga aaggaagctg gacccaagca acagccgact accgaaggtt 1250

 gcctggagca gtgcagatgt gggaggaaga agggccttgg tgcacactgg 1300

 cttttcttcc tgactgcaat gtggcattgt gccagctacc tcctctttct 1350

 cggcctcagg aaaatggaga gaaagcagcc ctgaaggtgg ctgtgacgag 1400

 ggaaggggca gagggcctga cagtcaacca cgcgctatat tttcctgttc 1450

 ttccttaggg caagaactgc atggccagac tcaggcaagg cctaggtgtg 1500

 ggctgggcat tgcctacacg tgaagagatc actccgcgtc cctactgcac 1550

 ctgtcacaaa gtgccttctg atatgcctgg caaaccaaaa tcggtgagcg 1600

 ccagcttgct tccctagaag acatttctaa atattcataa catgcttgct 1650

 caaatcaatc accttatttt acatccgctc cagggagaaa tgaagacatg 1700

 gtcctacgtt gttctgtaat tattttctat gtaaattttg ttccttgtta 1750

 caattatata tgtcttaggg gaaaggacca tttcacatgt gtcacctcat 1800

 gtgattctca ccacagccct gtgattgctc ctgttttata aataatgaca 1850

 tagttccagt tgatggccaa agccacagct aacgagaggc agagagagct 1900

 caggctccca ggagcttcca ctctcagacc ttgcctcccg ggctgccctg 1950

 agtgaaaccc ctgcttagca tttggcacag ccagaagcag caagctaggg 2000

 tcacaacaca gagaggggct gtgtaatact ggctgcctct gtgctaagaa 2050

 aaaaaaaaaa tcactgtgtg tttgtttatt ttggtgcagg cccagtgttc 2100

 ttgcttagac ttaatactac ccttcatgtt aaaataaaac caaacaaaaa 2150

 cccaaaaa 2158

<210> 4720
<211> 25
<212> PRT
<213> Homo sapien

<400> 4720
 Arg Arg Cys Thr Tyr Asn Ala Val Gly Gly Phe Asn Ser Ile Thr
   1               5                  10                  15

 Phe Gly Leu Cys Gly Trp Cys Ser Pro Ser
                  20                  25

<210> 4721
<211> 5726
<212> DNA
<213> Homo sapien

<400> 4721
 cggcacgtgg actcccttta atccagtgac tgtcaggtcg atcatatgcc 50

 gaggacgatg atcccgccgg gggagtgcac gtacgcgggc cggaagcgga 100

 ggaggcccct gcagaaacag aggcccgccg tgggggcaga gaagtccaac 150

 ccctccaagc gacaccggga ccgcctcaac gccgagttgg accacctggc 200

 cagcctgctg ccgttcccgc ctgacatcat ctccaagctg gacaagcttt 250

 ctgtcctgcg cctcagtgtc agttacctcc gggtgaagag cttcttccaa 300

 gtcgtgcagg agcagagctc acggcagcct gcggccggcg ccccctcgcc 350

 cggagacagc tgtcctcttg cagggtctgc cgtgctggag ggaaggctgc 400

 tgttggagtc tcttaatggc tttgctctgg tcgtgagtgc agaagggacg 450

 atattttatg catcagcaac gatcgtggac tatctgggct tccatcagac 500

 ggatgtaatg caccagaaca tttatgacta catccacgtg gacgaccgcc 550

 aggacttctg ccggcagctc cactgggcca tggaccctcc ccaggtggtg 600

 tttgggcagg ccccgccctt ggagacagga gatgatgcta tcctggggag 650

 gctgctcagg gcccaggagt ggggcacagg cacgcccacc gagtactcgg 700

 ccttcctgac ccgctgcttc atctgccgtg tgcgctgcct gctggacagc 750

 acctcgggct tcctggcccg ggggtcacag gcttggcagc tgcggctctg 800

 ctgtcccgag ccactcatga cgatgcagtt tcaaggaaaa ctaaaattcc 850

 tgtttggaca gaagaagaag gcgccgtcag gagccatgct cccgccgcgg 900

 ctgtcgctgt tctgcattgc ggcacccgtt ctcctcccct ccgcagcgga 950

 gatgaaaatg aggagcgcgc tcctgagggc aaaacccaga gcagacaccg 1000

 cagccaccgc ggatgcaaaa gtaaaagcca ccaccagtct gtgcgaatcg 1050

 gaactgcatg gaaaacccaa ttactcagca ggaaggagca gcagagagag 1100

 cggcgttttg gtgctcaggg aacagactga cgctggccga tgggcacagg 1150

 ttcccgccag ggccccatgc ctgtgcctcc ggggtggccc tgaccttgtc 1200

 cttgacccca aggggggctc aggggacagg gaggaggagc agcacaggat 1250

 gctgagcagg gcctctggag tgacagggcg gagggagact ccaggaccca 1300

 caaagcccct gccctggaca gcgggaaagc acagtgagga tggtgccagg 1350

 ccgaggctgc agcccagcaa gaatgacccg ccctccctgc gccccatgcc 1400

 ccgcggctcc tgcctgccct gcccgtgtgt ccagggcact ttcaggaact 1450

 cgcccatctc tcacccgccg agcccgtccc ccagtgccta ctccagccgg 1500

 accagcagac ccatgcggga tgtcggtgag gaccaggtgc accctcccct 1550

 ctgccacttt ccccagagga gcctgcagca ccagctccct cagcctggag 1600

 ctcagcgttt tgccacgagg ggctatccca tggaggacat gaagctgcaa 1650

 ggtgtaccga tgcctccggg ggacctgtgt ggtccgacgc tgctgctaga 1700

 tgtgtccatc aagatggaga aggactctgg gtgtgagggt gctgcagacg 1750

 gctgtgtgcc cagccaggtg tggctggggg ccagtgacag gagccaccca 1800

 gccaccttcc ctaccaggat gcacctgaaa acagagccag actctcggca 1850

 acaggtgtac atctcgcacc tggggcacgg cgtgcggggg gctcagcccc 1900

 atgggagggc cactgctggg cgcagcaggg agctgacccc tttccaccct 1950

 gcacactgtg cctgcctgga gcccacagac ggccttcccc agtcggagcc 2000

 tccccaccag ctctgtgcac ggggccgagg tgaacagtcc tgcacctgca 2050

 gagctgctga ggccgcccct gtggtcaagc gggagccctt ggactcaccc 2100

 cagtgggcta ctcacagcca gggaatggtg cccgggatgt tgcccaaaag 2150

 tgccttggcc acgctggtcc cgccccaagc ttcggggtgc acattcctgc 2200

 catagcgcag tgaccaccat ccaagctcag atctgtctgt ctacgctcag 2250

 atgcgtcggt ggctgggctg ccctgctcct ggtcaggccg gagcccgtcc 2300

 taagacacac tctttgcaga gctgtgcatg cgcagtctgc tagtgtgtgt 2350

 gtgcagcata cgcaggagcc tatcctgaat tttgtaaaat atcccaacag 2400

 ttcttaaatg aaaactggcc ttaagtctat tcaagcatga cagcatttct 2450

 ctttgaggaa ttaaaatctt taggaaagtg atcatggctg gacagcttca 2500

 tgccccagag gcagcgagca cccgtcccat ggctgccaag tccacagtcg 2550

 gggatgaagc agtcgggtga tgctcccaag tccgcagtcg gggatgaagc 2600

 ggtcgggtga tgctcccaag tccgcagtcg gggatgaagc ggtcgggtga 2650

 cacacctagc tcagccctcc caggccacct gcagctccca gcctgtgctg 2700

 tgcaggcagg gtcagcccat cgccacagtg cactgtagag gccagcacac 2750

 ggcaaattag aaatacaaca cgcggagaaa ggggtccgtg agcccactca 2800

 tagaggaatc tagaatgttc caggcagcag aggctggcag cgtgggtccc 2850

 acactgcccc acaccgtgcg gcaggtgctc catggcgcca tgacagagtc 2900

 tgaggccaga cctggactgg aattgacagc ataacccctg ttccttctgg 2950

 acatctcccg agttctcagt gggtctctgc ggacggttct tcctaatctg 3000

 cctcttggta catcacgtaa tacagagttc acagactccg ggtttggaag 3050

 tacagagaaa cacacaacgt agagagaaga cacaggaaac tgcgctgcct 3100

 gtgggggttt ctctctggct ggctgtacag ttcactcaaa tgagggttcc 3150

 cattgccatc ctaggagaat aattagggac aagacagaca agtattaata 3200

 gcattaaaac agttgtaaag gcgatatttt ctgagagtag gaaatttgga 3250

 tacaaaagca taagtcagaa agtgaaggtc accaatccac caacccgaga 3300

 acctacagct gatggtgcat ttcaggcttc ttccacggtc tggcctggaa 3350

 ccccacccgg ctggtgcagg catcagatca gggtgtagaa gtcaccccaa 3400

 gcaagaggaa gccaggcagt gaggccctgg ggtgtggctg cagctgggcc 3450

 cacctgtgcg ggggtgggaa ggccccatcc tcagggagag ggcatcggcg 3500

 ccctgacgtc agctccactg ggagtggcag gagctgtggg agcccatggg 3550

 tgagggaccc accaccccgc tgcactgtgc attgtgcctc ccgtgtggac 3600

 gccctctctg ttgttggccc gcgggtgagg gacccaccac cccgctgcac 3650

 tgtgcattgt gcctcccgtg tggacgccct ctctgttgtt ggcccgcggg 3700

 tgagggaccc accaccccta gggacccacc accccgccgc actgtgcatt 3750

 ctgcctcctg tgtggacgcc ctctctgttg tcagtggctt tgaggtgtca 3800

 gtgcttactt agatgctggt ttaatgctgg acccatttgt taaacgcacc 3850

 ttcactttgt caaaacccag gtttggttgg caggactggg tcttctgccc 3900

 aatgccaggt gcctgcgcct ctcagtggcc tggttcttgg acagtttgcc 3950

 cccatgtggc agggataggg ataaggatct cctctcagta ctggaggaga 4000

 acagccaacc atctgagccc agagtcacag atccatcgtg gccccctatg 4050

 acccccaagc cctaccgagg gggcactcac tctctgctta gccagggggc 4100

 gtctttcaaa aggtgacctc catgctgtgc tgtcgtgggt gtgagacgtg 4150

 ctcatggcct tccactgcca tctctccctt atctgatgcc taaagtcacg 4200

 atggggacag agctacccag gggccagcca tggggtgacc agccacctga 4250

 gggtcagtca cctgtggaga gcaggcacct gtgaagacca ggcacctgag 4300

 gactggcgcc tacttcccac tttggcccta cactggcaca gagcccctct 4350

 ttattcattt ctcatgctga gcatggcaca cttctggcct ctgggcattt 4400

 atggatttaa gaccaggatg gtatttcaga agcttcccac ttccttccta 4450

 ttctaaccga gtgcccagct cctttgctga tcatggaaag acccttaata 4500

 attaggcctg caggccaggc gcagtggctc atgcctataa tcccagcact 4550

 ttaggaggtc aaggtaggag gatcgcttaa gcccaggagt tcaagaccag 4600

 cctgggcaac acaggaagaa tgtgtctcta caaaaaataa ttaaaaatca 4650

 gatctgctgt atccctgaaa aagtctcaat caacatgcat gttccactct 4700

 tggagttccc tgttctgagg gccagccacg tcctgtgtcc tggagcttag 4750

 ccctcagcag ctcccttcag cctgggcgcc gcctgggtcc caaacgtggc 4800

 agctgctctt ccagtctcgg ggccgaggag ggcagggagc tcagtgactg 4850

 agagtcttgt gtatcacatg tcttgagtgt cctggagcca acggctgtca 4900

 ctgggaaaaa caccaggccc caaagatcga atcagagacg tggctgcgtg 4950

 tttgcgattg tagccaggcc cttcagtgtc atcaaaggag cactggggcc 5000

 tccttaagca cagacggcag cccctgccca ggaggcttct tcaccacgtc 5050

 ctgccctgca gcctcccaga cctttagatg cgcccctgcc caaggccctc 5100

 ctggtgacag gtgccagatt gagtggtggg ttgctgccag gcaggccacg 5150

 ctgtgttgac gctgcactca gcacgtgggt gttggctctg ccggttttgt 5200

 ggtgtgggga ccctacagga ggctgcggcc ctgagagcct gggatcagcg 5250

 aggtgtccga catcccttcc tcaacggcaa caaaaactcc ccaagtcagc 5300

 actttggtta ttttatagcc acaaccctct tggaaaacag tggggaagac 5350

 tatggaacat agaaagtgtg gatgtatcac ttctctctaa aatgtcattg 5400

 ttagcactaa ttacaggttc atgtttttct gtttatgtag cttttcccta 5450

 tatagctgaa aaagtattaa agtcaaatat aaggtgggaa tgggatggaa 5500

 gggaggagat caatacaact tatatttttg cagtttctac tggaagaaaa 5550

 aagttttcaa tacctagacc aacttgttga atttttaaaa cttatgcact 5600

 ataaatgcaa ctttctctac tgctttctca gtgcctttag gaagctttca 5650

 aatttttttg tactgtggtt tgtattaaat ttgcaatatt gatgtaaaat 5700

 acatgacatg ctagtacatg tttaac 5726

<210> 4722
<211> 2428
<212> DNA
<213> Homo sapien

<400> 4722
 gaaaacattt tgctgaaaat ataagcaaac atcggccttg tcctccttgt 50

 gttcatacac tgtggaagct tttctctgcc tcctccgtga gagtgcgtgg 100

 ccgggagacc agaaacgtgg tcctttctct tgcctgtgag ctggtgcaga 150

 gatggaggaa gaagaatatg aacaaattcc ccaggagaat cccccagaag 200

 agctgtccca ggatcctgtg ctggagctgt caggaggtct aagggagaaa 250

 gaacagaaga ccccaaggag actgaggctc attctcatgg ggaaaacagg 300

 gagtgggaag agtgcaacag gaaacagcat cctcggcagg gacgtcttcg 350

 agtctaaact cagcaccaga cccgtgacca agacctccca gagacggagc 400

 cgagagtggg ctgggaagga gcttgaggtg attgacacac ccaacattct 450

 gtccccccag gtctcgccag aggtggcaga cgctatctgc caagccatcg 500

 tcttatccgc cccagggccc cacgccgtgc tcctggtgac acaactgggc 550

 cggttcacgg atgaggatca gcaggtggtc aggcgcctgc aggaggtctt 600

 tggagtgggg gttctgggtc acaccatcct ggtgttcacc cggaaggaag 650

 acctggctgg cagctccctg gaagactatg tgcgagagac caacaaccag 700

 gcccttgcct ggctggatgt gacccttgca cggcgccatt gcggcttcaa 750

 caacagggca cagggggagg agcaggaggc ccaactgcga gagctcatgg 800

 agaaagttga agccattatg tgggaaaacg aaggagatta ttacagcaac 850

 aaggcttacc aatataccca gcaaaacttt cggctgaaag aactacagga 900

 aaggcaagta agccagggcc aaggctctga ggacgtgcct ggtgaggagt 950

 cttggctgga aggactgtcc cagatccaga aggaatctga ggaagcccac 1000

 agatgcctgc tggggaaggc tgacctttga gcctgtgctg gacttgagcc 1050

 aaggacacca tcagcctttg cacccccctg tgtccagccc tctgtttctc 1100

 tttccatccc atggagtgct tcccagtctc caggtcatga cgtctggtgt 1150

 aggaagaggg gcatggggct tgaggacagg gtccagcatg cccagatcac 1200

 attccagttc cttcattcct tcttccagaa catctgggtc ctccctcctc 1250

 tgtgccccaa cagcacgctg tcttcctatt ggaccttcta tctcattggc 1300

 attgcctttc atgagttact tgtctatact ctgatagaac caaagtttct 1350

 tgagggcagg cctgtatctt ttacttctgt gtaacttcca cagcttttga 1400

 ctgcattgga gtcatgcagt cacgtttggt gcggcaactc catgcaagct 1450

 gttgaccaga tgacttctca tctctcccca caccatgatg gtttaaggtg 1500

 cctgttgtgt ctggtggaga cagtgctggg agatgatcag aaatctcagg 1550

 gcacagcctc aggtctacct ggacactcat ccactgttgg agatgctcaa 1600

 cagctagaca cagatgctca cagccgacct gtggcctctt gctctgaagc 1650

 catcccccat cttccctaga cacagcagac atctgagaaa gcttcagcat 1700

 ttctcttgct aacagattca gaaaagtgtc tcaaagcaga gcacagagtt 1750

 atttggtgtt tgctgaagac agcctttgtg ccacaatcac ttattaaata 1800

 agcgatcaat ttcccattga actgaacatg caacatttat catacattca 1850

 gttctcattc acactcctta agatttggtc agaattttta tttctgttca 1900

 tgtcttctac ttttctactc ctgtatgaat aaaatattga tttgattaca 1950

 gtggctttga ctataatgtg ggagccaatt tttgcctcag tcttcatttt 2000

 tatatttacc ttgttattct caggcatttt tttcttctat gtgagagtta 2050

 aaatcattct gtaatttccc cccaaaatca tattggtatt ctagttggca 2100

 atgtcttaca tttatgttaa gtttgaggga attggtagtt caagtataag 2150

 ttaattaagg ccattttatt tctaagtgaa cagacttgaa actccagagc 2200

 tactgaagta aaagttagaa tcatttgcat tttcattcag ataggagata 2250

 attttgtaaa ttttgatgct attattttaa ctctattagc ttaagtaatg 2300

 tcataataga aaacacaagc atttgaccaa atgagatcca ttcagcgact 2350

 aactggcaag gcactcaaaa catgtcattc attaaatgtt gtttttattt 2400

 acctcaaaaa aaaaaaaaaa aaaaaaaa 2428

<210> 4723
<211> 292
<212> PRT
<213> Homo sapien

<400> 4723
 Met Glu Glu Glu Glu Tyr Glu Gln Ile Pro Gln Glu Asn Pro Pro
   1               5                  10                  15

 Glu Glu Leu Ser Gln Asp Pro Val Leu Glu Leu Ser Gly Gly Leu
                  20                  25                  30

 Arg Glu Lys Glu Gln Lys Thr Pro Arg Arg Leu Arg Leu Ile Leu
                  35                  40                  45

 Met Gly Lys Thr Gly Ser Gly Lys Ser Ala Thr Gly Asn Ser Ile
                  50                  55                  60

 Leu Gly Arg Asp Val Phe Glu Ser Lys Leu Ser Thr Arg Pro Val
                  65                  70                  75

 Thr Lys Thr Ser Gln Arg Arg Ser Arg Glu Trp Ala Gly Lys Glu
                  80                  85                  90

 Leu Glu Val Ile Asp Thr Pro Asn Ile Leu Ser Pro Gln Val Ser
                  95                 100                 105

 Pro Glu Val Ala Asp Ala Ile Cys Gln Ala Ile Val Leu Ser Ala
                 110                 115                 120

 Pro Gly Pro His Ala Val Leu Leu Val Thr Gln Leu Gly Arg Phe
                 125                 130                 135

 Thr Asp Glu Asp Gln Gln Val Val Arg Arg Leu Gln Glu Val Phe
                 140                 145                 150

 Gly Val Gly Val Leu Gly His Thr Ile Leu Val Phe Thr Arg Lys
                 155                 160                 165

 Glu Asp Leu Ala Gly Ser Ser Leu Glu Asp Tyr Val Arg Glu Thr
                 170                 175                 180

 Asn Asn Gln Ala Leu Ala Trp Leu Asp Val Thr Leu Ala Arg Arg
                 185                 190                 195

 His Cys Gly Phe Asn Asn Arg Ala Gln Gly Glu Glu Gln Glu Ala
                 200                 205                 210

 Gln Leu Arg Glu Leu Met Glu Lys Val Glu Ala Ile Met Trp Glu
                 215                 220                 225

 Asn Glu Gly Asp Tyr Tyr Ser Asn Lys Ala Tyr Gln Tyr Thr Gln
                 230                 235                 240

 Gln Asn Phe Arg Leu Lys Glu Leu Gln Glu Arg Gln Val Ser Gln
                 245                 250                 255

 Gly Gln Gly Ser Glu Asp Val Pro Gly Glu Glu Ser Trp Leu Glu
                 260                 265                 270

 Gly Leu Ser Gln Ile Gln Lys Glu Ser Glu Glu Ala His Arg Cys
                 275                 280                 285

 Leu Leu Gly Lys Ala Asp Leu
                 290

<210> 4724
<211> 614
<212> DNA
<213> Homo sapien

<400> 4724
 agacggaaag ggtgccgccc atcatagaag taccagaact tgagctggac 50

 tttgctgatt tagcttatgg aagaggaacc agaaatttgt ccttgaataa 100

 tgtttcccgt gttgggctgg atcttgatag cagttgttat catcattctt 150

 ctgattttta catctgtcac ccgatgccta tctccagtta gttttctgca 200

 gctgaaattc tggaaaatct atttggaaca ggagcagcag atccttaaaa 250

 gtaaagccac agagcatgca actgaattgg caaaagagaa tattaaatgt 300

 ttctttgagg gctcgcatcc aaaagaatat aacactccaa gcatgaaaga 350

 gtggcagcaa atttcatcac tgtatacttt caatccgaag ggccagtact 400

 acagcatgtt gcacaaatat gtcaacagaa aagagaagac tcacagtatc 450

 aggtctactg aaggagatac ggtgattcct gttcttggct ttgtagattc 500

 atctggtata aacagcactc ctgagttatg accttttgaa tgagtagaaa 550

 aaaaaattgt tttgaattat tgctttatta aaaaataaac attggtattt 600

 tttgagtgct tttt 614

<210> 4725
<211> 143
<212> PRT
<213> Homo sapien

<400> 4725
 Met Phe Pro Val Leu Gly Trp Ile Leu Ile Ala Val Val Ile Ile
   1               5                  10                  15

 Ile Leu Leu Ile Phe Thr Ser Val Thr Arg Cys Leu Ser Pro Val
                  20                  25                  30

 Ser Phe Leu Gln Leu Lys Phe Trp Lys Ile Tyr Leu Glu Gln Glu
                  35                  40                  45

 Gln Gln Ile Leu Lys Ser Lys Ala Thr Glu His Ala Thr Glu Leu
                  50                  55                  60

 Ala Lys Glu Asn Ile Lys Cys Phe Phe Glu Gly Ser His Pro Lys
                  65                  70                  75

 Glu Tyr Asn Thr Pro Ser Met Lys Glu Trp Gln Gln Ile Ser Ser
                  80                  85                  90

 Leu Tyr Thr Phe Asn Pro Lys Gly Gln Tyr Tyr Ser Met Leu His
                  95                 100                 105

 Lys Tyr Val Asn Arg Lys Glu Lys Thr His Ser Ile Arg Ser Thr
                 110                 115                 120

 Glu Gly Asp Thr Val Ile Pro Val Leu Gly Phe Val Asp Ser Ser
                 125                 130                 135

 Gly Ile Asn Ser Thr Pro Glu Leu
                 140

<210> 4726
<211> 1029
<212> DNA
<213> Homo sapien

<400> 4726
 atggagaagt ttcgggcggt gctggacctg cacgtcaagc accacagcgc 50

 cttgggctac ggcctggtga ccctgctgac ggcgggcggg gagcgcatct 100

 tctccgccgt ggcattccag tgcccgtgca gcgccgcctg gaacctgccc 150

 tacggcctgg tcttcttgct ggtgccggcg ctcgcgctct tcctcctggg 200

 ctacgtgctg agcgcacgca cgtggcgcct gctcaccgga tgctgctcca 250

 gcgcccgcgc gagttgcgga tcggcgctgc gcggctccct ggtgtgcacg 300

 caaatcagcg cggccgccgc gctcgcgccc ctcacctggg tggccgtggc 350

 gctgctcggg ggcgcctttt acgagtgcgc ggccaccggg agcgcggcct 400

 tcgcgcagcg cctgtgcctc ggccgcaacc gcagctgcgc cgcggagctg 450

 ccgctggtgc cgtgcaacca ggccaaggcg tcggacgtgc aggacctcct 500

 gaaggatctg aaggctcagt cgcaggtgtt gggctggatc ttgatagcag 550

 ttgttatcat cattcttctg atttttacat ctgtcacccg atgcctatct 600

 ccagttagtt ttctgcagct gaaattctgg aaaatctatt tggaacagga 650

 gcagcagatc cttaaaagta aagccacaga gcatgcaact gaattggcaa 700

 aagagaatat taaatgtttc tttgagggct cgcatccaaa agaatataac 750

 actccaaggc atgaaaagag gtggcagcaa atttcatcac tgtatacttt 800

 caatccgaag ggccagtact acagcatgtt gcacaaatat gtcaacagaa 850

 aagagaagac tcacagtatc aggtctactg aaggagatac ggtgattcct 900

 gttcttggct ttgtagattc atctggtata aacagcactc ctgagttatg 950

 accttttgaa tgagtagaaa aaaaaattgt tttgaattat tgctttatta 1000

 aaaaataaac attggttaaa aaagaaaaa 1029

<210> 4727
<211> 316
<212> PRT
<213> Homo sapien

<400> 4727
 Met Glu Lys Phe Arg Ala Val Leu Asp Leu His Val Lys His His
   1               5                  10                  15

 Ser Ala Leu Gly Tyr Gly Leu Val Thr Leu Leu Thr Ala Gly Gly
                  20                  25                  30

 Glu Arg Ile Phe Ser Ala Val Ala Phe Gln Cys Pro Cys Ser Ala
                  35                  40                  45

 Ala Trp Asn Leu Pro Tyr Gly Leu Val Phe Leu Leu Val Pro Ala
                  50                  55                  60

 Leu Ala Leu Phe Leu Leu Gly Tyr Val Leu Ser Ala Arg Thr Trp
                  65                  70                  75

 Arg Leu Leu Thr Gly Cys Cys Ser Ser Ala Arg Ala Ser Cys Gly
                  80                  85                  90

 Ser Ala Leu Arg Gly Ser Leu Val Cys Thr Gln Ile Ser Ala Ala
                  95                 100                 105

 Ala Ala Leu Ala Pro Leu Thr Trp Val Ala Val Ala Leu Leu Gly
                 110                 115                 120

 Gly Ala Phe Tyr Glu Cys Ala Ala Thr Gly Ser Ala Ala Phe Ala
                 125                 130                 135

 Gln Arg Leu Cys Leu Gly Arg Asn Arg Ser Cys Ala Ala Glu Leu
                 140                 145                 150

 Pro Leu Val Pro Cys Asn Gln Ala Lys Ala Ser Asp Val Gln Asp
                 155                 160                 165

 Leu Leu Lys Asp Leu Lys Ala Gln Ser Gln Val Leu Gly Trp Ile
                 170                 175                 180

 Leu Ile Ala Val Val Ile Ile Ile Leu Leu Ile Phe Thr Ser Val
                 185                 190                 195

 Thr Arg Cys Leu Ser Pro Val Ser Phe Leu Gln Leu Lys Phe Trp
                 200                 205                 210

 Lys Ile Tyr Leu Glu Gln Glu Gln Gln Ile Leu Lys Ser Lys Ala
                 215                 220                 225

 Thr Glu His Ala Thr Glu Leu Ala Lys Glu Asn Ile Lys Cys Phe
                 230                 235                 240

 Phe Glu Gly Ser His Pro Lys Glu Tyr Asn Thr Pro Arg His Glu
                 245                 250                 255

 Lys Arg Trp Gln Gln Ile Ser Ser Leu Tyr Thr Phe Asn Pro Lys
                 260                 265                 270

 Gly Gln Tyr Tyr Ser Met Leu His Lys Tyr Val Asn Arg Lys Glu
                 275                 280                 285

 Lys Thr His Ser Ile Arg Ser Thr Glu Gly Asp Thr Val Ile Pro
                 290                 295                 300

 Val Leu Gly Phe Val Asp Ser Ser Gly Ile Asn Ser Thr Pro Glu
                 305                 310                 315

 Leu


<210> 4728
<211> 1421
<212> DNA
<213> Homo sapien

<400> 4728
 agcggagccc cgagccgccc gcagagcaag cgcggggaac caaggagacg 50

 ctcctggcac tgcagataac ttgtctgcat ttcaagaaca acctaccaga 100

 gaccttacct gtcaccttgg ctctcccacc caatggagat ggctctaatg 150

 gtggcacaaa ccaggaaggg gaaatctgtg gtttaaattc tttatgcctc 200

 atcctctgag tgctgaaggc ttgctgtagg ctgtatgctg ttaatgctaa 250

 tcgtgatagg ggtttttgcc tccaactgac tcctacatat tagcattaac 300

 agtgtatgat gcctgttact agcattcaca tggaacaaat tgctgccgtg 350

 ggaggatgac aaagaagcat gagtcaccct gctggataaa cttagacttc 400

 aggctttatc atttttcaat ctgttaatca taatctggtc actgggatgt 450

 tcaaccttaa actaagtttt gaaagtaagg ttatttaaaa gatttatcag 500

 tagtatccta aatgcaaaca ttttcattta aatgtcaagc ccatgtttgt 550

 ttttatcatt aacagaaaat atattcatgt cattcttaat tgcaggtttt 600

 ggcttgttca ttataatgtt cataaacacc tttgattcaa ctgttagaaa 650

 tgtgggctaa acacaaattt ctataatatt tttgtagtta aaaattagaa 700

 ggactactaa cctccagtta tatcatggat tgtctggcaa cgttttttaa 750

 aagatttaga aactggtact ttcccccagg taacgatttt ctgttcaggc 800

 aacttcagtt taaaattaat acttttattt gactcttaaa gggaaactga 850

 aaggctatga agctgaattt ttttaatgaa atatttttaa cagttagcag 900

 ggtaaataac atctgacagc taatgagata ttttttccat acaagataaa 950

 aagatttaat caaaaatttc atatttgaaa tgaagtccca aatctaggtt 1000

 caagttcaat agcttagcca cataatacgg ttgtgcgagc agagaatcta 1050

 cctttccact tctaagcctg tttcttcctc cataaaatgg ggataatact 1100

 ttacaaggtt gttgtgaggc ttagatgaga tagagaatta ttccataaga 1150

 taatcaagtg ctacattaat gttatagtta gattaatcca agaactagtc 1200

 accctacttt attagagaag agaaaagcta atgatttgat ttgcagaata 1250

 tttaaggttt ggatttctat gcagtttttc taaataacca tcacttacaa 1300

 atatgtaacc aaacgtaatt gttagtatat ttaatgtaaa cttgttttaa 1350

 caactcttct caacattttg tccaggttat tcactgtaac caaataaatc 1400

 tcatgagtct ttagttgatt t 1421

<210> 4729
<211> 68
<212> PRT
<213> Homo sapien

<400> 4729
 Arg Ser Pro Glu Pro Pro Ala Glu Gln Ala Arg Gly Thr Lys Glu
   1               5                  10                  15

 Thr Leu Leu Ala Leu Gln Ile Thr Cys Leu His Phe Lys Asn Asn
                  20                  25                  30

 Leu Pro Glu Thr Leu Pro Val Thr Leu Ala Leu Pro Pro Asn Gly
                  35                  40                  45

 Asp Gly Ser Asn Gly Gly Thr Asn Gln Glu Gly Glu Ile Cys Gly
                  50                  55                  60

 Leu Asn Ser Leu Cys Leu Ile Leu
                  65

<210> 4730
<211> 2024
<212> DNA
<213> Homo sapien

<400> 4730
 gcccgtgagt tttttaccat gctgctctga ccagtttgag tggcaattac 50

 caatagattt gttttcttta ttctatggag atgtttttac cactgacact 100

 gttttctgat tatagtctgc ttcatagaaa atagcctgca taatcaaaca 150

 aggagttact ttgaaattaa agtatgcctg gctattaaaa atgcagattt 200

 taggtgggta aacatcaggt aggtctgggt gggtcatgtt ctaggcctag 250

 aaaaatacac tattagacaa gttctaaaga aggcaaggag ataaaggcat 300

 caggtggtaa cttctaattg aatattatat gttgatcata cataatatat 350

 actatgcctg gaaattatga ctgaaaagca cctattcggt tagtgctcct 400

 attcatgaga acatatctcc aatactaaat gagataagcc tgttctaaaa 450

 tcttatagcc agtattttaa gaaacttgat tatacttacc aaaggaacat 500

 tgtttgtttt ctcttgtttt aaatatggag aggtttaatc ctttacataa 550

 caaaggaatt aattttagca aaatgattca ttccaacctt cttataagaa 600

 atatctagga gagtcaagta agaaaaataa cgaatctaag tgataaacat 650

 tcaagaaatt ctctaaataa gagatttatt tataatttta atatctcagg 700

 gttcttttta ggtttccagg ggaaaagagc aggataacag tgtggagact 750

 gctaagttga gaatttaaaa caaatgagaa cataagattt ttaaaattgc 800

 attgtgaatg taaaattttt atcaatcctt tgctctcttt tagacatatt 850

 gagaaaatgt taaatagaaa aaattaagta ttttaataag atgtttcaga 900

 tctttgagta tgaaaaacat aacaaaaaag cctaatttca aaaaactatt 950

 tgagatcaag ggacaatggt gtgaccaata tgaagggtca agactgaaat 1000

 gtattgtctt tactatcaag aactctactt tcagttgttt ctcagacagt 1050

 taatttcagc ttcatagaga tttctgagca aattaagaaa cactgttttc 1100

 ctgggtttgt tttgggtata tgtcattata gttatgttat ttcttgttga 1150

 aatttataat tgtaggtttt ttgtattgtt ttagtattta atggtgtata 1200

 atgtgttatt acattatatg tagttatacc aaaatattgc ctgaagataa 1250

 atcatgacaa ggtcccctgt ttattcctgt gttacagacg catggaattg 1300

 ctcctgtaga tttgaatttt tgtttcattt ttttctgtcc cacccttcac 1350

 tctctctgtt tcagaacatt tttggtagaa gtgctatcca gaagtgaact 1400

 tgtcaaaagg caagtagcat gaaagaagac agaagaagca aaaggctaat 1450

 acagtggata atttctgagc acttgaagtt tcttcaaatg tgcaagactg 1500

 tgtgtcttcc tattagatgt ataaattgga tatttcatgc ctaattaaat 1550

 gttgcgttgg attgcagtgc ctatcataca gcgattggag taaattgagg 1600

 cctaatcctg aacacatata gagcatattg ttagatattt ttcctgtgac 1650

 atttgaagtt attattctcc catttccttt ttcttttttt gtttataatc 1700

 atatgtccct aagattgttt tccttttttg gaccaaaaaa aagaaaaaaa 1750

 aaatcttagc ttttcatcct cccagtgtat tctgcattgt ccttacccta 1800

 gatcagcccc ttctgtgtaa cagtttttct cacaatgtag caacttttat 1850

 ccacccttca ggaccttcac tggggactag ttcattcatt ttcaaatagc 1900

 tatttcaacc tttaacatct actggtctta gtcttttaca cagaagccag 1950

 agtgactggg tctgggcaag actctggtgg tggtatcacc actcgtaacc 2000

 ttactggatt ggtttcagca aatt 2024

<210> 4731
<211> 35
<212> PRT
<213> Homo sapien

<400> 4731
 Pro Val Ser Phe Leu Pro Cys Cys Ser Asp Gln Phe Glu Trp Gln
   1               5                  10                  15

 Leu Pro Ile Asp Leu Phe Ser Leu Phe Tyr Gly Asp Val Phe Thr
                  20                  25                  30

 Thr Asp Thr Val Phe
                  35

<210> 4732
<211> 579
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 80-119
<223> Unknown base

<400> 4732
 ggtgaaatgg ggatggaaaa gggttatata aaaacaaata atggtaacaa 50

 taatgatgaa gattggagta ctccatctcn nnnnnnnnnn nnnnnnnnnn 100

 nnnnnnnnnn nnnnnnnnnc atgttcatta tagttcatta cagttacata 150

 gtccgaaggt cttacaacta atcactggta gcaataaatg cttcaggccc 200

 acatgatgct gattagttct cagttttcat tcagttcaca atataaccac 250

 cattcctgcc ctccctgcca agggtcataa atggtgactg cctaacaaca 300

 aaatttgcag tctcatctca ttttcatcca gacttctgga actcaaagat 350

 taacttttga ctaaccctgg aatatctctt atctcactta tagcttcagg 400

 catgtattta tatgtattct tgatagcaat accataatca atgtgtattc 450

 ctgatagtaa tgctacaata aatccaaaca tttcaactct gttagaatag 500

 aggtaattgt gtggtttgtg tatgggacta taacagtaat attaattccc 550

 aaaatttctc ctactaggaa cagtgggta 579

<210> 4733
<211> 56
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 27-40
<223> unknown amino acid

<220>
<221> Unsure
<222> 80-119
<223> Unknown amino acid

<400> 4733
 Gly Glu Met Gly Met Glu Lys Gly Tyr Ile Lys Thr Asn Asn Gly
   1               5                  10                  15

 Asn Asn Asn Asp Glu Asp Trp Ser Thr Pro Ser Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Met Phe Ile Ile Val
                  35                  40                  45

 His Tyr Ser Tyr Ile Val Arg Arg Ser Tyr Asn
                  50                  55

<210> 4734
<211> 4898
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 4221, 4288
<223> Unknown base

<400> 4734
 ctccacgctg tgcagcggat caacaaagcc atccggagga gagtggcggc 50

 tgacactgtg aaggagctga tgtgccctga ggcccagctg cctccagtgt 100

 accctgttgc atcgtctatg taccagctgg agctggcagt gctccagcag 150

 cagcaggggg agcttggcca ggaggagctc ttcgtggctg tggagatgct 200

 ctcagctgtg gtcctgatta accgggccct ggaggcccgg gatgccagtg 250

 gcttctggag cagcctggtg aaccctgcca caggcctggc tgaggtggaa 300

 ggagaaaatg cccagcgtta cttcgatgcc ctgctgaaat tgcgacagga 350

 gcgtgggatg ggtgaggact tcctgagctg gaatgacctg caggccaccg 400

 tgagccaggt caatgcacag acccaggaag agactgaccg ggtccttgca 450

 gtcagcctca tcaatgaggc tctggacaaa ggcagccctg agaagactct 500

 gtctgcccta ctgcttcctg cagctggcct agatgatgtc agcctccctg 550

 tcgcccctcg gtaccatctc ctccttgtgg cagccaaaag gcagaaggcc 600

 caggtgacag gggatcctgg agctgtgctg tggcttgagg agatccgcca 650

 gggagtggtc agagccaacc aggacactaa tacagctcag agaatggctc 700

 ttggtgtggc tgccatcaat caagccatca aggagggcaa ggcagcccag 750

 actgagcggg tgttgaggaa ccccgcagtg gcccttcgag gggtagttcc 800

 cgactgtgcc aacggctacc agcgagccct ggaaagtgcc atggcaaaga 850

 aacagcgtcc agcagacaca gctttctggg ttcaacatga catgaaggat 900

 ggcactgcct actacttcca tctgcagacc ttccagggga tctgggagca 950

 acctcctggc tgccccctca acacctctca cctgacccgg gaggagatcc 1000

 agtcagctgt caccaaggtc actgctgcct atgaccgcca acagctctgg 1050

 aaagccaacg tcggctttgt tatccagctc caggcccgcc tccgtggctt 1100

 cctagttcgg cagaagtttg ctgagcattc ccactttctg aggacctggc 1150

 tcccagcagt catcaagatc cagatccagg cctgggcccg gatgtgggca 1200

 gctcggaggc aatacctgag gcgtctgcac tacttccaga agaatgttaa 1250

 ctccattgtg aagatccagg catttttccg agccaggaaa gcccaagatg 1300

 actacaggat attaggtgag ctgcctgatc caccctcccc agctgttggg 1350

 agggagagga ccccacagag ccaggcaggt ctagacatcc ttctgcgact 1400

 gcacagcagt gtggtacgca gatttgccca tctcttgaat caaagccagc 1450

 aagacttctt ggctgaggca gagctgctga agctccagga agaggtagtt 1500

 aggaagatcc gatccaatca gcagctggag caggacctca acatcatgga 1550

 catcaagatt ggcctgctgg tgaagaaccg gatcactctg caggaagtgg 1600

 tctcccactg caagaagctg accaagagga ataaggaaca gctgtcagat 1650

 atgatggttc tggacaagca gaagggttta aagtcgctga gcaaagagaa 1700

 acggcagaaa ctagaagcat accaacacct cttctacctg ctccagactc 1750

 agcccatcta cctggccaag ctgatctttc agatgccaca gaacaaaacc 1800

 accaagttca tggaggcagt gattttcagc ctgtacaact atgcctccag 1850

 ccgccgagag gcctatctcc tgctccagct gttcaagaca gcactccagg 1900

 aggaaatcaa gtcaaaggtg gagcagcccc aggacgtggt gacaggcaac 1950

 ccaacagtgg tgaggctggt ggtgagattc taccgtaatg ggcggggaca 2000

 gagtgccctg caggagattc tgggcaaggt tatccaggat gtgctagaag 2050

 acaaagtgct cagcgtccac acagaccctg tccacctcta taagaactgg 2100

 atcaaccaga ctgaggccca gacagggcag cgcagccatc tcccatatga 2150

 tgtcaccccg gagcaggcct tgagccaccc cgaggtccag agacgactgg 2200

 acatcgccct acgcaacctc ctcgccatga ctgataagtt ccttttagcc 2250

 atcacctcat ctgtggacca aattccgtat gggatgcgat atgtggccaa 2300

 agtcctgaag gcaactctgg cagagaaatt ccctgacgcc acagacagcg 2350

 aggtctataa ggcaagtgtt gtctccccac ccccacctcc caatccctcc 2400

 tttgctttgc tggtggtcgg gaacctcctg tactaccgct tcctgaaccc 2450

 agctgtggtg gctcctgacg ccttcgacat tgtggccatg gcagctggtg 2500

 gagccctggc tgccccccag cgccatgccc tgggggctgt ggctcagctc 2550

 ctacagcacg ctgcggctgg caaggccttc tctgggcaga gccagcacct 2600

 acgggtcctg aatgactatc tggaggaaac acacctcaag ttcaggaagt 2650

 tcatccatag agcctgccag gtgccagagc cagaggagcg ttttgcagtg 2700

 gacgagtact cagacatggt ggctgtggcc aaacccatgg tgtacatcac 2750

 cgtgggggag ctggtcaaca cgcacaggct gttgctggag caccaggact 2800

 gcattgcccc tgatcaccaa gaccccctgc atgagctcct ggaggatctt 2850

 ggggagctgc ccaccatccc tgaccttatt ggtgagagca tcgctgcaga 2900

 tgggcacacg gacctgagca agctagaagt gtccctgacg ctgaccaaca 2950

 agtttgaagg actagaggca gatgctgatg actccaacac ccgtagcctg 3000

 cttctgagca ccaagcagct gttggccgat atcatacagt tccatcctgg 3050

 ggacaccctc aaggagatcc tgtccctctc ggcttccaga gagcaagaag 3100

 cagcccacaa gcagctgatg agccgacgcc aggcctgtac agcccagaca 3150

 ccggagccac tgcgacgaca ccgctcactg acagctcact ccctcctgcc 3200

 actggcagag aagcagcggc gcgtcctgcg gaacctgcgc cgacttgaag 3250

 ccctggggtt ggtcagcgcc agaaatggct accaggggct agtggacgag 3300

 ctggccaagg acatccgcaa ccagcacaga cacaggcaca ggcggaaggc 3350

 agagctggtg aagctgcagg ccacattaca gggcctgagc actaagacca 3400

 ccttctatga ggagcagggt gactactaca gccagtacat ccgggcctgc 3450

 ctggaccacc tggcccccga ctccaagagt tctgggaagg ggaagaagca 3500

 gccttctctt cattacactg ctgctcagct cctggaaaag ggtgtcttgg 3550

 tggaaattga agatcttccc gcctctcact tcagaaacgt catctttgac 3600

 atcacgccgg gagatgaggc aggaaagttt gaagtaaatg ccaagttcct 3650

 gggtgtggac atggagcgat ttcagcttca ctatcaggat ctcctgcagc 3700

 tccagtatga gggtgtggct gtcatgaaac tcttcaacaa ggccaaagtc 3750

 aatgtcaacc ttctcatctt cctcctcaac aagaagtttt tgcggaagtg 3800

 acagaggcaa agggtgctac ccaagcccct cttacctctc tggatgcttt 3850

 ctttaacact aactcaccac tgtgcttccc tgcagacacc cagagctcag 3900

 gactgggcaa ggcccaggga ttctcacccc ttccccagct gggaggagct 3950

 tgcctgcctg gccacagaca gtgtatcttc taattggcta aagtgggcct 4000

 tgcccagagt ccagctgtgt ggcttttatc atgcatgaca aacccctggc 4050

 tttcctgcca gatggtagga catggacctt gacctgggaa agccattact 4100

 cttgtgtctg ctactgccct cccacagtca ccccaatatt acaagcactg 4150

 ccccagcggc ttgatttccc ctctgccttc cttctctctg cactcccaca 4200

 aagccagggc caggctcccc ntccctacct cccactgcat cagcagtggg 4250

 tgttcctgcc cttcctgagt ctaggcagct ctgctgtngt gatctgcaca 4300

 ccctccaacc tgggcaggga ctggggggat gcagtgtgtg ttagtgccca 4350

 tgtggcattg tggcactgtt gccccccatg gcggcatggg caagatgacc 4400

 ttccattagc ttcaagtctt gttctcttgt ctgtggtctg tttaatatgt 4450

 gggtcactag ggtatttatt ctttctccca tccttacact ctggatcatt 4500

 gtgcagactt aatcagcgtc gatacgactt tttttttttt tttttttttt 4550

 ttttttgagc tcaaagagag ttctcatttt ccctattcaa actaataccc 4600

 atgccgtgtt ttttaccttg gatttaaagt caccttaggt tggggcaaca 4650

 gattctcact catgtttaag atcttgttat ttcagcttca taagatcaaa 4700

 gaggagtctt tcccttttct cttttaccct caggattctc atcccttaca 4750

 gctgactctt ccaggcaatt tccatagatc tgcagtcctg cctctgccac 4800

 agtctctctg ttgtccccac atctacccaa cttcctgtac tgttgccctt 4850

 ctgtcgtctt ctcgcagccg tataactccc aaaaaaaaaa aaaaaaaa 4898

<210> 4735
<211> 1266
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 4221, 4288
<223> Unknown amino acid

<400> 4735
 Leu His Ala Val Gln Arg Ile Asn Lys Ala Ile Arg Arg Arg Val
   1               5                  10                  15

 Ala Ala Asp Thr Val Lys Glu Leu Met Cys Pro Glu Ala Gln Leu
                  20                  25                  30

 Pro Pro Val Tyr Pro Val Ala Ser Ser Met Tyr Gln Leu Glu Leu
                  35                  40                  45

 Ala Val Leu Gln Gln Gln Gln Gly Glu Leu Gly Gln Glu Glu Leu
                  50                  55                  60

 Phe Val Ala Val Glu Met Leu Ser Ala Val Val Leu Ile Asn Arg
                  65                  70                  75

 Ala Leu Glu Ala Arg Asp Ala Ser Gly Phe Trp Ser Ser Leu Val
                  80                  85                  90

 Asn Pro Ala Thr Gly Leu Ala Glu Val Glu Gly Glu Asn Ala Gln
                  95                 100                 105

 Arg Tyr Phe Asp Ala Leu Leu Lys Leu Arg Gln Glu Arg Gly Met
                 110                 115                 120

 Gly Glu Asp Phe Leu Ser Trp Asn Asp Leu Gln Ala Thr Val Ser
                 125                 130                 135

 Gln Val Asn Ala Gln Thr Gln Glu Glu Thr Asp Arg Val Leu Ala
                 140                 145                 150

 Val Ser Leu Ile Asn Glu Ala Leu Asp Lys Gly Ser Pro Glu Lys
                 155                 160                 165

 Thr Leu Ser Ala Leu Leu Leu Pro Ala Ala Gly Leu Asp Asp Val
                 170                 175                 180

 Ser Leu Pro Val Ala Pro Arg Tyr His Leu Leu Leu Val Ala Ala
                 185                 190                 195

 Lys Arg Gln Lys Ala Gln Val Thr Gly Asp Pro Gly Ala Val Leu
                 200                 205                 210

 Trp Leu Glu Glu Ile Arg Gln Gly Val Val Arg Ala Asn Gln Asp
                 215                 220                 225

 Thr Asn Thr Ala Gln Arg Met Ala Leu Gly Val Ala Ala Ile Asn
                 230                 235                 240

 Gln Ala Ile Lys Glu Gly Lys Ala Ala Gln Thr Glu Arg Val Leu
                 245                 250                 255

 Arg Asn Pro Ala Val Ala Leu Arg Gly Val Val Pro Asp Cys Ala
                 260                 265                 270

 Asn Gly Tyr Gln Arg Ala Leu Glu Ser Ala Met Ala Lys Lys Gln
                 275                 280                 285

 Arg Pro Ala Asp Thr Ala Phe Trp Val Gln His Asp Met Lys Asp
                 290                 295                 300

 Gly Thr Ala Tyr Tyr Phe His Leu Gln Thr Phe Gln Gly Ile Trp
                 305                 310                 315

 Glu Gln Pro Pro Gly Cys Pro Leu Asn Thr Ser His Leu Thr Arg
                 320                 325                 330

 Glu Glu Ile Gln Ser Ala Val Thr Lys Val Thr Ala Ala Tyr Asp
                 335                 340                 345

 Arg Gln Gln Leu Trp Lys Ala Asn Val Gly Phe Val Ile Gln Leu
                 350                 355                 360

 Gln Ala Arg Leu Arg Gly Phe Leu Val Arg Gln Lys Phe Ala Glu
                 365                 370                 375

 His Ser His Phe Leu Arg Thr Trp Leu Pro Ala Val Ile Lys Ile
                 380                 385                 390

 Gln Ile Gln Ala Trp Ala Arg Met Trp Ala Ala Arg Arg Gln Tyr
                 395                 400                 405

 Leu Arg Arg Leu His Tyr Phe Gln Lys Asn Val Asn Ser Ile Val
                 410                 415                 420

 Lys Ile Gln Ala Phe Phe Arg Ala Arg Lys Ala Gln Asp Asp Tyr
                 425                 430                 435

 Arg Ile Leu Gly Glu Leu Pro Asp Pro Pro Ser Pro Ala Val Gly
                 440                 445                 450

 Arg Glu Arg Thr Pro Gln Ser Gln Ala Gly Leu Asp Ile Leu Leu
                 455                 460                 465

 Arg Leu His Ser Ser Val Val Arg Arg Phe Ala His Leu Leu Asn
                 470                 475                 480

 Gln Ser Gln Gln Asp Phe Leu Ala Glu Ala Glu Leu Leu Lys Leu
                 485                 490                 495

 Gln Glu Glu Val Val Arg Lys Ile Arg Ser Asn Gln Gln Leu Glu
                 500                 505                 510

 Gln Asp Leu Asn Ile Met Asp Ile Lys Ile Gly Leu Leu Val Lys
                 515                 520                 525

 Asn Arg Ile Thr Leu Gln Glu Val Val Ser His Cys Lys Lys Leu
                 530                 535                 540

 Thr Lys Arg Asn Lys Glu Gln Leu Ser Asp Met Met Val Leu Asp
                 545                 550                 555

 Lys Gln Lys Gly Leu Lys Ser Leu Ser Lys Glu Lys Arg Gln Lys
                 560                 565                 570

 Leu Glu Ala Tyr Gln His Leu Phe Tyr Leu Leu Gln Thr Gln Pro
                 575                 580                 585

 Ile Tyr Leu Ala Lys Leu Ile Phe Gln Met Pro Gln Asn Lys Thr
                 590                 595                 600

 Thr Lys Phe Met Glu Ala Val Ile Phe Ser Leu Tyr Asn Tyr Ala
                 605                 610                 615

 Ser Ser Arg Arg Glu Ala Tyr Leu Leu Leu Gln Leu Phe Lys Thr
                 620                 625                 630

 Ala Leu Gln Glu Glu Ile Lys Ser Lys Val Glu Gln Pro Gln Asp
                 635                 640                 645

 Val Val Thr Gly Asn Pro Thr Val Val Arg Leu Val Val Arg Phe
                 650                 655                 660

 Tyr Arg Asn Gly Arg Gly Gln Ser Ala Leu Gln Glu Ile Leu Gly
                 665                 670                 675

 Lys Val Ile Gln Asp Val Leu Glu Asp Lys Val Leu Ser Val His
                 680                 685                 690

 Thr Asp Pro Val His Leu Tyr Lys Asn Trp Ile Asn Gln Thr Glu
                 695                 700                 705

 Ala Gln Thr Gly Gln Arg Ser His Leu Pro Tyr Asp Val Thr Pro
                 710                 715                 720

 Glu Gln Ala Leu Ser His Pro Glu Val Gln Arg Arg Leu Asp Ile
                 725                 730                 735

 Ala Leu Arg Asn Leu Leu Ala Met Thr Asp Lys Phe Leu Leu Ala
                 740                 745                 750

 Ile Thr Ser Ser Val Asp Gln Ile Pro Tyr Gly Met Arg Tyr Val
                 755                 760                 765

 Ala Lys Val Leu Lys Ala Thr Leu Ala Glu Lys Phe Pro Asp Ala
                 770                 775                 780

 Thr Asp Ser Glu Val Tyr Lys Ala Ser Val Val Ser Pro Pro Pro
                 785                 790                 795

 Pro Pro Asn Pro Ser Phe Ala Leu Leu Val Val Gly Asn Leu Leu
                 800                 805                 810

 Tyr Tyr Arg Phe Leu Asn Pro Ala Val Val Ala Pro Asp Ala Phe
                 815                 820                 825

 Asp Ile Val Ala Met Ala Ala Gly Gly Ala Leu Ala Ala Pro Gln
                 830                 835                 840

 Arg His Ala Leu Gly Ala Val Ala Gln Leu Leu Gln His Ala Ala
                 845                 850                 855

 Ala Gly Lys Ala Phe Ser Gly Gln Ser Gln His Leu Arg Val Leu
                 860                 865                 870

 Asn Asp Tyr Leu Glu Glu Thr His Leu Lys Phe Arg Lys Phe Ile
                 875                 880                 885

 His Arg Ala Cys Gln Val Pro Glu Pro Glu Glu Arg Phe Ala Val
                 890                 895                 900

 Asp Glu Tyr Ser Asp Met Val Ala Val Ala Lys Pro Met Val Tyr
                 905                 910                 915

 Ile Thr Val Gly Glu Leu Val Asn Thr His Arg Leu Leu Leu Glu
                 920                 925                 930

 His Gln Asp Cys Ile Ala Pro Asp His Gln Asp Pro Leu His Glu
                 935                 940                 945

 Leu Leu Glu Asp Leu Gly Glu Leu Pro Thr Ile Pro Asp Leu Ile
                 950                 955                 960

 Gly Glu Ser Ile Ala Ala Asp Gly His Thr Asp Leu Ser Lys Leu
                 965                 970                 975

 Glu Val Ser Leu Thr Leu Thr Asn Lys Phe Glu Gly Leu Glu Ala
                 980                 985                 990

 Asp Ala Asp Asp Ser Asn Thr Arg Ser Leu Leu Leu Ser Thr Lys
                 995                1000                1005

 Gln Leu Leu Ala Asp Ile Ile Gln Phe His Pro Gly Asp Thr Leu
                1010                1015                1020

 Lys Glu Ile Leu Ser Leu Ser Ala Ser Arg Glu Gln Glu Ala Ala
                1025                1030                1035

 His Lys Gln Leu Met Ser Arg Arg Gln Ala Cys Thr Ala Gln Thr
                1040                1045                1050

 Pro Glu Pro Leu Arg Arg His Arg Ser Leu Thr Ala His Ser Leu
                1055                1060                1065

 Leu Pro Leu Ala Glu Lys Gln Arg Arg Val Leu Arg Asn Leu Arg
                1070                1075                1080

 Arg Leu Glu Ala Leu Gly Leu Val Ser Ala Arg Asn Gly Tyr Gln
                1085                1090                1095

 Gly Leu Val Asp Glu Leu Ala Lys Asp Ile Arg Asn Gln His Arg
                1100                1105                1110

 His Arg His Arg Arg Lys Ala Glu Leu Val Lys Leu Gln Ala Thr
                1115                1120                1125

 Leu Gln Gly Leu Ser Thr Lys Thr Thr Phe Tyr Glu Glu Gln Gly
                1130                1135                1140

 Asp Tyr Tyr Ser Gln Tyr Ile Arg Ala Cys Leu Asp His Leu Ala
                1145                1150                1155

 Pro Asp Ser Lys Ser Ser Gly Lys Gly Lys Lys Gln Pro Ser Leu
                1160                1165                1170

 His Tyr Thr Ala Ala Gln Leu Leu Glu Lys Gly Val Leu Val Glu
                1175                1180                1185

 Ile Glu Asp Leu Pro Ala Ser His Phe Arg Asn Val Ile Phe Asp
                1190                1195                1200

 Ile Thr Pro Gly Asp Glu Ala Gly Lys Phe Glu Val Asn Ala Lys
                1205                1210                1215

 Phe Leu Gly Val Asp Met Glu Arg Phe Gln Leu His Tyr Gln Asp
                1220                1225                1230

 Leu Leu Gln Leu Gln Tyr Glu Gly Val Ala Val Met Lys Leu Phe
                1235                1240                1245

 Asn Lys Ala Lys Val Asn Val Asn Leu Leu Ile Phe Leu Leu Asn
                1250                1255                1260

 Lys Lys Phe Leu Arg Lys
                1265

<210> 4736
<211> 1523
<212> DNA
<213> Homo sapien

<400> 4736
 atgaagaggc ggcggcgccg gcgcccggtc gccccggcca cggccgcccg 50

 gggcggcgac tttagggcag aagacggggc tgggttggag gcgcgggagg 100

 agaaggtggt gtactcgcgg tcgcaactgt cgctggctga cagcaccaag 150

 gcgctgggcg acgccttcaa gctcttcatg ccccgcagca cggagttcat 200

 gagctcggac gcggagctct ggagcttcct ctgcagcctc aagcaccagt 250

 tctccccgca catcctgcgc agcaaggacg tctacggcta ctcctcctgc 300

 cgggccctgg tacccgaccc cccggggccc cctacagccc gcggccaggc 350

 gcgccggccg gttccgcgcg cagcggccag gaggaggcgc cgcggagccc 400

 gggcggccgc tgcccgcagg aggaagcccc ggccgccacc cccaccgccg 450

 ccgccccccg aggagagctg cccggccaag cccgtggccc ccgggccctg 500

 cttcgggggc cgcaccttgg aggagatctg gagggcggcc accccgacgc 550

 tgaccacctt ccccaccatc cgcgtcggca gcgacgtgtg gggcgagcgc 600

 agcctggcgg cagcgcggcg cagggcgcgc caggtcctgc gagtgaacct 650

 ggaacccatg gtgaggctcc gccgcttccc ggtgccccgg gcatgaggtg 700

 cggcctccag ggcgcctcct gccggccccg accttgggac aggccttccg 750

 cccggaggaa tgaacaagtg tcagtcgagt gtttacagat ccggccagga 800

 ccccggcccc caatgcactt tacgcgcgaa gaagttgccg gatggttgtc 850

 cctgtcccgg gccgcggcgc ggtcgtcttg gacgctgggg caggtgtgcc 900

 ctctgctgcc tcccgtaccc ggcctgcgga gggaggggac agctggaccc 950

 gcaggggagg tccctttctt cctgaccacc gattgagacg tctccaggac 1000

 cttaggggca gatccgtttt ctcactgttg gactctacct cactggtctg 1050

 gaagtcctcc gaagacatta tttttccaaa ggaatttggt ttcgtgcttg 1100

 tgtaataaag ccagaattta cttgttcttt atctccccct ttttctattt 1150

 cactgtcacc cctctttgtg gacagaagtt cgaacatgtg gtgttgcact 1200

 agtttgtgct cagggtattc tgaagcccac tcgtttccta atttttactg 1250

 gattccaaag ctttgatcga ggatattttt taagaggttc aagcttgtga 1300

 ctgttagtag tgcaaggatt tgtatgggct cagtgattac aaacaaagac 1350

 atgcaaaata caactgttta aacattttca aggtattttt aaaggttttg 1400

 tattgaaaca atgtttatat ttactgagct cctaaaaatg gtagaataca 1450

 catgaaaact tttgtttagg aaaagttaac ttgttaaatt cttttgaatt 1500

 gaataaaaaa atgcattgaa acc 1523

<210> 4737
<211> 231
<212> PRT
<213> Homo sapien

<400> 4737
 Met Lys Arg Arg Arg Arg Arg Arg Pro Val Ala Pro Ala Thr Ala
   1               5                  10                  15

 Ala Arg Gly Gly Asp Phe Arg Ala Glu Asp Gly Ala Gly Leu Glu
                  20                  25                  30

 Ala Arg Glu Glu Lys Val Val Tyr Ser Arg Ser Gln Leu Ser Leu
                  35                  40                  45

 Ala Asp Ser Thr Lys Ala Leu Gly Asp Ala Phe Lys Leu Phe Met
                  50                  55                  60

 Pro Arg Ser Thr Glu Phe Met Ser Ser Asp Ala Glu Leu Trp Ser
                  65                  70                  75

 Phe Leu Cys Ser Leu Lys His Gln Phe Ser Pro His Ile Leu Arg
                  80                  85                  90

 Ser Lys Asp Val Tyr Gly Tyr Ser Ser Cys Arg Ala Leu Val Pro
                  95                 100                 105

 Asp Pro Pro Gly Pro Pro Thr Ala Arg Gly Gln Ala Arg Arg Pro
                 110                 115                 120

 Val Pro Arg Ala Ala Ala Arg Arg Arg Arg Arg Gly Ala Arg Ala
                 125                 130                 135

 Ala Ala Ala Arg Arg Arg Lys Pro Arg Pro Pro Pro Pro Pro Pro
                 140                 145                 150

 Pro Pro Pro Glu Glu Ser Cys Pro Ala Lys Pro Val Ala Pro Gly
                 155                 160                 165

 Pro Cys Phe Gly Gly Arg Thr Leu Glu Glu Ile Trp Arg Ala Ala
                 170                 175                 180

 Thr Pro Thr Leu Thr Thr Phe Pro Thr Ile Arg Val Gly Ser Asp
                 185                 190                 195

 Val Trp Gly Glu Arg Ser Leu Ala Ala Ala Arg Arg Arg Ala Arg
                 200                 205                 210

 Gln Val Leu Arg Val Asn Leu Glu Pro Met Val Arg Leu Arg Arg
                 215                 220                 225

 Phe Pro Val Pro Arg Ala
                 230

<210> 4738
<211> 2994
<212> DNA
<213> Homo sapien

<400> 4738
 ggcctccgcc gccgcctcgg gaggtgagga cgaggaggaa gcgagcagcc 50

 cagacagcgg ccacctcaag gatggaatcc gacgtggtag gcccagagca 100

 gatactgtcc gcgatttaat aaatgaagga gagcattcat ccagcagaat 150

 ccgttgtaac atctgtaata gggtgtttcc acgggagaaa tcgctccagg 200

 ctcacaaaag gactcataca ggtgagaggc cctatctgtg tgactatcca 250

 gactgtggaa aagcctttgt tcaaagtgga cagctcaaaa cacatcagcg 300

 tcttcacacc ggagagaaac ctttgtttgt tcagaaaatg gctgcctgag 350

 cagattcacc catgcaaacc gccactgtcc gaagcacccc tacgccaggc 400

 tgaagagaga ggagcccacg gacacactca gcaaacatca ggctgccgac 450

 aacaaggccg cggccgagtg gctggcgagg tattgggaaa tgagagagca 500

 gcgcaccccc actttgaaag gcaagctggt tcagaaggct gatcaggagc 550

 agcaggaccc tctggaatac cttcagtctg atgaagagga cgacgagaag 600

 agaggggccc agcgccggct gcaggagcag cgggagcgcc tgcatggagc 650

 cctcgcgctc atagagcttg ccaacctgac tggggcgcca ctccgacagt 700

 agcttggaca ctgactcttc cactgtacaa aagtactgcc cagcatactt 750

 aaaaagtaga tccttgggca taagctaagc accttatttg cttatcatag 800

 gctgctattc tgtagaaatt tatgaagaat gttattgccc cagaatatgg 850

 ggtgagagag aactgcactt ttttaatatg gaaatgaatt catcgtaaag 900

 tttaaaatat tttgtaaata tggactgcac agtacagggt agaaaactac 950

 atattgtggg aagctagatt ttgcaagttt aatgcattca ttggaagcag 1000

 ttctcacagg aagcactttc tgaataagac acttgtttga aaaacagaat 1050

 ggtacaaata gccaaagaag attaaaacag attatttata agatcatttt 1100

 taacaatata tattagtatg tttaacaata ctgtaaacac tgaagcaagc 1150

 aagaaagtat aaaatatgta agatagataa ttttaattgc aaaatactgt 1200

 gcccactaag gctagagaaa tgggaggcta ttttggaaga tgttctaagt 1250

 aatggactta gaagaaaata gatatttgag gctcttggta agatgcacaa 1300

 tagttcagaa tttttgaaat tggagcaaaa tcagtcttat tctatctggg 1350

 gctttacaac tcagtataat gtttaagttt gaaaagcact tgtcatccct 1400

 agcatgttaa cttgggaact tttgcacatt tcatatttct catttgctga 1450

 aattgagtga ttaatcttgc aaagtctagg taacatagta attggtaatt 1500

 ttaaaaatac atattaaggg ccctgtaatg agatttggca cttggatttt 1550

 tactaaaggg acacctgcag ggttgttttg tagtgaaatg ttttagatct 1600

 tttgttagca aacactacat tttaattgta ctgcttgttt agaattatta 1650

 gcaaatggaa gcctccatat ttatattttc agtgcataaa gccaccttct 1700

 tgctttactt cagagtaaca tgccaagcta ttttgtgttc actaaattta 1750

 gctatcagtt aaacactgca gaaaatatta gctactcaaa taagtaggct 1800

 tctgaaatag ttttaactgc aagtgtgtta acttgtgtgg tggtttgaag 1850

 ccatttttcc aaataaagtt attaaacacc actttatgta ctgaagcatg 1900

 aacagaaaaa tcaagagctg agcagaccac ctcctttatg taggcaaaac 1950

 ttccatcatt ttggcttttg ttctaaacag aactaaatga catgcatagc 2000

 atggtaactt acagatcgct taattggagt aaaactcaga gtaatagagg 2050

 gaaatatggg ctcttcagtg cctttttagc ttttttgagt tgaagacgtt 2100

 cctacagatg tagtttaaac attacaaagt aggcttcttt atccaaaaat 2150

 cccaatgtgt catagtacac agatagttta aaatatgtag ccacggggaa 2200

 ggggaggcat gtaaatgtct tgaagaggag aaaaagtatg aaagaagata 2250

 cgatagttac gaataatgtg tatgatgagg acatacttta aaaatgtaat 2300

 tcctctgtac agtaaattac aaatctttag ggattttttt gtaataagag 2350

 aatttatatt tgtaatggtc taagaatttt tttgtaatgt ggtatataga 2400

 attttaattt ggagcactta taagctggta agagagacta tagcatctga 2450

 attatcttgg tttatgtttc agcatttcct ctagaatttt tgctctcaaa 2500

 tatgtgattt aatgaactaa aaacaacact catcagtctt gggaaatttg 2550

 aactttgatc aacttaacta aagaaggaag ggtagtaaga atttttcaaa 2600

 tacaaatatt tgccaattca cagatgataa catttaaggc cttcaaaagt 2650

 aagggttttt ccttgtttct ccagtcagct tttgtcaact ctaatagttt 2700

 tttcataaac attttttatt tgtataattg caacagttta agaaattatc 2750

 acaactattt agaaacattt aaaatgttct ttttgatata agctatatac 2800

 ttggaaaaat acattggtat ctaaaatttg aggtgtgtta agactgcttt 2850

 ttgttttaaa aaatggttta cattcaaatt tttgaagtgt tttatgcttc 2900

 atatggctaa gttgtagttt ggcagagtta acagcataag aataaacatg 2950

 ctgtaatttt aaaagatgct ttgaataaaa atttatttta attt 2994

<210> 4739
<211> 139
<212> PRT
<213> Homo sapien

<400> 4739
 Met Lys Glu Ser Ile His Pro Ala Glu Ser Val Val Thr Ser Val
   1               5                  10                  15

 Ile Gly Cys Phe His Gly Arg Asn Arg Ser Arg Leu Thr Lys Gly
                  20                  25                  30

 Leu Ile Gln Val Arg Gly Pro Ile Cys Val Thr Ile Gln Thr Val
                  35                  40                  45

 Glu Lys Pro Leu Phe Lys Val Asp Ser Ser Lys His Ile Ser Val
                  50                  55                  60

 Phe Thr Pro Glu Arg Asn Leu Cys Leu Phe Arg Lys Trp Leu Pro
                  65                  70                  75

 Glu Gln Ile His Pro Cys Lys Pro Pro Leu Ser Glu Ala Pro Leu
                  80                  85                  90

 Arg Gln Ala Glu Glu Arg Gly Ala His Gly His Thr Gln Gln Thr
                  95                 100                 105

 Ser Gly Cys Arg Gln Gln Gly Arg Gly Arg Val Ala Gly Glu Val
                 110                 115                 120

 Leu Gly Asn Glu Arg Ala Ala His Pro His Phe Glu Arg Gln Ala
                 125                 130                 135

 Gly Ser Glu Gly


<210> 4740
<211> 2496
<212> DNA
<213> Homo sapien

<400> 4740
 gttgttctct cgcggcgcga ccgcctcagt cacttcgccc agagacccgg 50

 acctggtccg ctggggagca ggcggccata aaccccctct ctcccggttc 100

 cctgacgccg cggcaggagc tgttacaaac accctgcggt tggtctccga 150

 tgcccttcag tgaggtgggg acgcctggac cctggtgagc gaaccccaag 200

 ccacccccca ccccaactca gtgtcttcgc cggcccccgg cccgtacgcc 250

 tgtctggtcg ccatggctga aaacacagag ggggatctga actccaacct 300

 gctccacgcc ccctaccaca ccggggaccc tcagctggac acggccatcg 350

 ggcagtggct ccgctgggat aagaatccca aaacaaaaga gcagattgaa 400

 aacctgttac ggaatgggat gaacaaggag ctgcgagatc gtctttgttg 450

 ccgaatgact tttggggctg caggacttcg ttctgccatg ggggcagggt 500

 tttgctatat taatgacctt acagtaatac agtcaacaca ggggatgtac 550

 aaataccttg agagatgttt ctcagacttc aagcagagag gctttgtggt 600

 tgggtatgac actcggggtc aagtaactag cagctgcagc agccagaggc 650

 ttgctaaact cactgctgca gtcttgctgg ccaaagatgt tcctgtgtac 700

 cttttttcaa gatatgttcc tacacctttt gtaccatatg cagttcagaa 750

 gctcaaagca gttgcaggtg tgatgattac tgcctctcac aaccgcaagg 800

 aagacaatgg atacaaggtt tactgggaaa ctggtgctca gatcacatct 850

 cctcatgata aagaaattct aaaatgtata gaagaatgtg tggaaccctg 900

 gaatggttcc tggaatgata atttagtgga taccagcccg ctgaagagag 950

 accctctgca ggacatttgc aggagataca tggaagatct gaaaaagatc 1000

 tgtttttaca gggagttaaa ctcgaagacc accttgaaat ttgtgcacac 1050

 atcttttcat ggggtcggac atgactatgt gcagttggct tttaaagtgt 1100

 ttggttttaa gcctccaatt ccagtaccag aacaaaaaga tcctgatcca 1150

 gacttttcta ccgttaaatg tccaaatcct gaagaaggag aatctgtgct 1200

 ggaactttcc ttgagactgg cagagaaaga aaatgcccgg gtagtgctag 1250

 ccacagatcc tgatgcagac agactggcag cagcagaact tcaggagaat 1300

 ggttgttgga aagttttcac agggaatgag ttggcagctt tgtttggatg 1350

 gtggatgttt gattgctgga agaaaaataa atcaagaaat gctgatgtga 1400

 agaacgttta tatgttagcc accacagtct cttctaaaat tctgaaggca 1450

 attgcactta aagaaggatt tcattttgaa gaaacattac caggttttaa 1500

 atggattgga agtaggataa tagacctcct ggaaaatggg aaagaagtcc 1550

 tttttgcatt tgaagagtct attggttttc tctgtggaac ttcagttttg 1600

 gataaagatg gggtgagtgc agctgttgtg gttgctgaga tggcatctta 1650

 cctggaaacc atgaatataa cattgaaaca gcaactggtt aaggtttatg 1700

 aaaaatatgg ttatcatatt tcaaaaactt cctatttctt gtgttatgaa 1750

 ccacctacca tcaaaagtat atttgaaagg cttcgtaatt ttgattctcc 1800

 aaaagaatat ccaaaatttt gtggaacatt tgctatattg catgtacggg 1850

 acattaccac tggatatgac agtagccagc ctaataagaa atcagtgctg 1900

 cctgtgagta aaaacagcca aatgattaca tttacttttc aaaatggctg 1950

 tgttgctacc cttcggacaa gtggaacaga accaaagata aagtattatg 2000

 cagagatgtg tgcgtcacct gaccagagtg acactgcttt actggaggaa 2050

 gaactgaaga aactcattga tgctctgata gagaattttc ttcagcctag 2100

 taagaatgga ctgatctggc gttctgttta ggggtacacc aatatgtcat 2150

 gacactgtgt gggcatatgg aacagagcaa ccgagaactg catacattga 2200

 accttgtgtt agcattctct ctctatctca tctggccgag tatctttttc 2250

 cttttatttt ctttcttttt ggtcaactgg ctagactaaa caaagtataa 2300

 gtttgaaatg aaatggtcta gagggaaatg attcaaattt tttcataatt 2350

 caaacaaaag ttattacact aaaagtatta tagtaacgta ttgtccttcc 2400

 gttaacagaa acatcacaat tcaaaagtga gttttcttat tatagtgtga 2450

 ttaagcctag ttctgtatct cgtaattgtg tatagcatgg taaaag 2496

<210> 4741
<211> 622
<212> PRT
<213> Homo sapien

<400> 4741
 Met Ala Glu Asn Thr Glu Gly Asp Leu Asn Ser Asn Leu Leu His
   1               5                  10                  15

 Ala Pro Tyr His Thr Gly Asp Pro Gln Leu Asp Thr Ala Ile Gly
                  20                  25                  30

 Gln Trp Leu Arg Trp Asp Lys Asn Pro Lys Thr Lys Glu Gln Ile
                  35                  40                  45

 Glu Asn Leu Leu Arg Asn Gly Met Asn Lys Glu Leu Arg Asp Arg
                  50                  55                  60

 Leu Cys Cys Arg Met Thr Phe Gly Ala Ala Gly Leu Arg Ser Ala
                  65                  70                  75

 Met Gly Ala Gly Phe Cys Tyr Ile Asn Asp Leu Thr Val Ile Gln
                  80                  85                  90

 Ser Thr Gln Gly Met Tyr Lys Tyr Leu Glu Arg Cys Phe Ser Asp
                  95                 100                 105

 Phe Lys Gln Arg Gly Phe Val Val Gly Tyr Asp Thr Arg Gly Gln
                 110                 115                 120

 Val Thr Ser Ser Cys Ser Ser Gln Arg Leu Ala Lys Leu Thr Ala
                 125                 130                 135

 Ala Val Leu Leu Ala Lys Asp Val Pro Val Tyr Leu Phe Ser Arg
                 140                 145                 150

 Tyr Val Pro Thr Pro Phe Val Pro Tyr Ala Val Gln Lys Leu Lys
                 155                 160                 165

 Ala Val Ala Gly Val Met Ile Thr Ala Ser His Asn Arg Lys Glu
                 170                 175                 180

 Asp Asn Gly Tyr Lys Val Tyr Trp Glu Thr Gly Ala Gln Ile Thr
                 185                 190                 195

 Ser Pro His Asp Lys Glu Ile Leu Lys Cys Ile Glu Glu Cys Val
                 200                 205                 210

 Glu Pro Trp Asn Gly Ser Trp Asn Asp Asn Leu Val Asp Thr Ser
                 215                 220                 225

 Pro Leu Lys Arg Asp Pro Leu Gln Asp Ile Cys Arg Arg Tyr Met
                 230                 235                 240

 Glu Asp Leu Lys Lys Ile Cys Phe Tyr Arg Glu Leu Asn Ser Lys
                 245                 250                 255

 Thr Thr Leu Lys Phe Val His Thr Ser Phe His Gly Val Gly His
                 260                 265                 270

 Asp Tyr Val Gln Leu Ala Phe Lys Val Phe Gly Phe Lys Pro Pro
                 275                 280                 285

 Ile Pro Val Pro Glu Gln Lys Asp Pro Asp Pro Asp Phe Ser Thr
                 290                 295                 300

 Val Lys Cys Pro Asn Pro Glu Glu Gly Glu Ser Val Leu Glu Leu
                 305                 310                 315

 Ser Leu Arg Leu Ala Glu Lys Glu Asn Ala Arg Val Val Leu Ala
                 320                 325                 330

 Thr Asp Pro Asp Ala Asp Arg Leu Ala Ala Ala Glu Leu Gln Glu
                 335                 340                 345

 Asn Gly Cys Trp Lys Val Phe Thr Gly Asn Glu Leu Ala Ala Leu
                 350                 355                 360

 Phe Gly Trp Trp Met Phe Asp Cys Trp Lys Lys Asn Lys Ser Arg
                 365                 370                 375

 Asn Ala Asp Val Lys Asn Val Tyr Met Leu Ala Thr Thr Val Ser
                 380                 385                 390

 Ser Lys Ile Leu Lys Ala Ile Ala Leu Lys Glu Gly Phe His Phe
                 395                 400                 405

 Glu Glu Thr Leu Pro Gly Phe Lys Trp Ile Gly Ser Arg Ile Ile
                 410                 415                 420

 Asp Leu Leu Glu Asn Gly Lys Glu Val Leu Phe Ala Phe Glu Glu
                 425                 430                 435

 Ser Ile Gly Phe Leu Cys Gly Thr Ser Val Leu Asp Lys Asp Gly
                 440                 445                 450

 Val Ser Ala Ala Val Val Val Ala Glu Met Ala Ser Tyr Leu Glu
                 455                 460                 465

 Thr Met Asn Ile Thr Leu Lys Gln Gln Leu Val Lys Val Tyr Glu
                 470                 475                 480

 Lys Tyr Gly Tyr His Ile Ser Lys Thr Ser Tyr Phe Leu Cys Tyr
                 485                 490                 495

 Glu Pro Pro Thr Ile Lys Ser Ile Phe Glu Arg Leu Arg Asn Phe
                 500                 505                 510

 Asp Ser Pro Lys Glu Tyr Pro Lys Phe Cys Gly Thr Phe Ala Ile
                 515                 520                 525

 Leu His Val Arg Asp Ile Thr Thr Gly Tyr Asp Ser Ser Gln Pro
                 530                 535                 540

 Asn Lys Lys Ser Val Leu Pro Val Ser Lys Asn Ser Gln Met Ile
                 545                 550                 555

 Thr Phe Thr Phe Gln Asn Gly Cys Val Ala Thr Leu Arg Thr Ser
                 560                 565                 570

 Gly Thr Glu Pro Lys Ile Lys Tyr Tyr Ala Glu Met Cys Ala Ser
                 575                 580                 585

 Pro Asp Gln Ser Asp Thr Ala Leu Leu Glu Glu Glu Leu Lys Lys
                 590                 595                 600

 Leu Ile Asp Ala Leu Ile Glu Asn Phe Leu Gln Pro Ser Lys Asn
                 605                 610                 615

 Gly Leu Ile Trp Arg Ser Val
                 620

<210> 4742
<211> 3677
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 611-653, 848-883
<223> Unknown base

<400> 4742
 attttttcat ttccctatat tttttgttaa aacattaata actctcttat 50

 tagctgtgag ccaccgcgcc tggccctctg cagttgttta ataaggcaca 100

 gaatacctgt agcataggtc agccttacga tgtccatgaa ttacatattc 150

 agacgtttta gagcctgata cattttggaa aagaaaaaca acttctacac 200

 ctattctaca gtccgcattt aaaacaataa attcctctat taaaaacgta 250

 aagccgggtt tgcttgcgtg ccacagggaa tatatccagg aaggttatta 300

 tgaagctgtc aaatcaagat gatgggaata aggcagtttg aacgaacagt 350

 cttcccacag tcaggccatt tttgctgatt tggtttagaa ttttcagaaa 400

 tacttagtac actccacctg ttctttgatg ggaatatcta agaaggctag 450

 gtaggttctt agggttagcc tgagtcatct aggggctcaa ctccttgtga 500

 ggggaaatga cagtgaacaa gttagtactt tgctccacaa atgcatgaaa 550

 ggacaaattt gcatcttcta tcagtattta acttcctttt gctaatgaca 600

 aataaatata nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 650

 nnnctctctt attgtttggc caacaatata gccaacaata agagagtttt 700

 taatgtttta acaacaattt taaaggccac agagcaaacc atttttccca 750

 tggattaata gggatgcttc ggatggtttt gattgcaagg tctttactgt 800

 gcaaagcaag cactgcctgt gcttgtggaa accaccggac aagagggnnn 850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntgcttat gtttttataa 900

 gcatagccaa aggtctggaa ttttgtggct ggaggggggc ctgtctcgtt 950

 catctccatt ttgcagaggt ggtgactgaa gccactgagt gtcggtgctt 1000

 tactcatggt catccagttg atccctcagt ggcagaacca ggcctgggag 1050

 cctgtttctg gctgcctggt ccagtgcgct ttgggaggtc acaacccaaa 1100

 cctagtctgg ggcaagacct ccctttggga gatggcctct gatatttttg 1150

 gagcaccagg tcttccttag tgtttgagac cgtctcggag ctgactggct 1200

 ttcacatgag aaacagttgg gtctgtgtta catgtgtgtc tattatttta 1250

 tgggataata gttcagggcc gtcaggggga aactcagtcc aggtagctca 1300

 cagagggacc cactgtacat aagcgagcat gacctgtgca ggctgcactc 1350

 ctttgcagag ttgtctgatg tcctgtgggc catgctgatg cgcgtgggcc 1400

 tccgcgttga caccacctat ggcgtcttgc tactgctccc ggttatcgcg 1450

 ctctttgcag ttttgaccat tttcatcctt ctgatcatgg aagggctttc 1500

 tgcgtttctt cacgccatac gcctccactg gtgagtttga aacctagcct 1550

 tggagctgtt atttaaaaaa catacccgcc ccaccatgcc tggccaaaat 1600

 atgcaaatat tttttatcct gtgctaccta gaattacaag tagaggattg 1650

 tttttacaat tttgtcttgt tttagtaatt ggggacaatg ggataaaatg 1700

 acatacaaca aatggttatc ccacttgtat atttttttaa agactcttat 1750

 cctgttaccc ttacataaaa ccagttatga taattgtatg tttggaagat 1800

 aaattgtatg ctgagcctta aaacccagtg tgactgtaga agatataatg 1850

 cggacatgat ttgaatttag tgacagcttg gctgatgtca ctgaaccaga 1900

 agggtttata ctgagtgaag gaaaggtaaa aagtagtatt ttgtatattt 1950

 ttgtaacaaa atataaatga agatatttta ccatgaagag attgcactta 2000

 tccttgagaa cagtctaaat ataaatgaag atattttacc atgaagagat 2050

 tgcacttatc cttgagaaca gtctaatgat acttttttta ctttcagact 2100

 gtttctagct aaagttctga taaaagtatt gagttaattt aaactttcaa 2150

 acactgttta gatcagttga aaactaattc ttaatagcca ttgttttata 2200

 atctttagtt taaattcatc tgtttgacat ttggtttttt gtgaacttga 2250

 gtcagtccta ttgaacattt tgacctatat tcttgcaaat tatgttaatt 2300

 tttcatattt tagtttgatt ttagacaatt attttcaaaa agaaacctga 2350

 ctttttttca ccttcttgac attgtgagtg atacacgtta aaaggctatt 2400

 tgcccgcatc ctcctctatc ctgtttcgag gtagagagct tggcacttct 2450

 gttacaagct gagagtctgg aggtgctgag tttaacgtgg ctgtgcaggt 2500

 gatttcaagg catgagctga acagcgttga cacagccgtg acttacaatt 2550

 aaaccctttc aattacagta cagattctgt gtgctacttg atgagatgtt 2600

 acccaaggcc agtttggact tactgctttt tgtccctcat attaaattat 2650

 caaatgatgc cgatgaaatg cttgaaaatg attctgctct caaagttatg 2700

 cttccctaga aaggtgtcat gtcgggcact tgtgttgggt gactatgaca 2750

 tcccagcagt gctggtcagg tctcagagtt gctttcacct agagctgatg 2800

 cttccacaag gggacatttg tgttactttg ctccaggggt ctgtcataaa 2850

 aacaatggta actacttcat ccctaggaag cccaagactt cagggcactg 2900

 ttagctgatt ggtaaataag ggacacgata ttcacgggaa ttgtttactg 2950

 ctccccacta gtaattctca tggggccact tttttaactc tttctaatta 3000

 acacctcttc tcagcataga gcagaggatg cagtcatttc tctgttgaaa 3050

 tctatgtagt atttatgtag aatgtcatta tatgaaaagc gaattcagaa 3100

 tcctaactct gggaaagcgc tctctggaaa tgtagtttga taatagtgtc 3150

 ttataggggc cacgggaatt tgtttctcta taaagcgatg ggctccagtg 3200

 tcatgttacc agagttatcg ctcagttttg tttgttaagg cttttgctag 3250

 aacctattat gtatccagtt tttaaaacat acttcattcc cttgatagca 3300

 gagatccaga gcacagatgg caagttgtgt ggatgatact gaatatgttt 3350

 attttcctaa agataaatgt cacgacacga catttctcag tttttattta 3400

 gatgtttatt accatgtgtt aacagaatct taaaacccaa gggatttctt 3450

 cagtaaacta gactttgatt caacctgctg ggctggagac tgtaattgcc 3500

 gtggtcagtt aaggagtgca aagggtgttc tgtctgatag gatctgggtg 3550

 agccctgcgg actttccagc agcgaaagga cttggaactc ctctttcgct 3600

 gaatgctgct ctgtttctgg aatggatatt ttataacaac attctggtgt 3650

 cagcatcccc tcagcagttg tttattt 3677

<210> 4743
<211> 105
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 611-653, 848-883
<223> Unknown amino acid

<400> 4743
 Met Arg Cys Tyr Pro Arg Pro Val Trp Thr Tyr Cys Phe Leu Ser
   1               5                  10                  15

 Leu Ile Leu Asn Tyr Gln Met Met Pro Met Lys Cys Leu Lys Met
                  20                  25                  30

 Ile Leu Leu Ser Lys Leu Cys Phe Pro Arg Lys Val Ser Cys Arg
                  35                  40                  45

 Ala Leu Val Leu Gly Asp Tyr Asp Ile Pro Ala Val Leu Val Arg
                  50                  55                  60

 Ser Gln Ser Cys Phe His Leu Glu Leu Met Leu Pro Gln Gly Asp
                  65                  70                  75

 Ile Cys Val Thr Leu Leu Gln Gly Ser Val Ile Lys Thr Met Val
                  80                  85                  90

 Thr Thr Ser Ser Leu Gly Ser Pro Arg Leu Gln Gly Thr Val Ser
                  95                 100                 105

<210> 4744
<211> 3666
<212> DNA
<213> Homo sapien

<400> 4744
 actggttaca aaaggcagcg agaatatgaa gaggaagatg acgatgatga 50

 tgaatacgac tctgaaatgg aagattttat tgaagatgaa ggagagcctc 100

 aggaagaaat atccaggcac attagagaaa tctttggtta tgaccgaaaa 150

 aaatacaaag atgaaagtga ttatgcctta cgttacatgg aaagtagttg 200

 gaaagagcag cagaaggaag aagcaaagag cttaagactg ggtatgcaag 250

 aggacttaga ggaaatgaga cgtgaagaag aagaaatgca acgtcgaagg 300

 gccaagaagc tgaagaggcg ttagctgctg cttttatttt tgtgaaattc 350

 tagagctgct ctgctgcaag gatttcctgc cttcagactg aagaagcccc 400

 cttatcattt tagatttata cttgggtact caaggagaag gaatgcatac 450

 tgtcatttgc aggctgtcat ttgagcataa aatattttca gatattttcc 500

 agggtgaaat ctgtaatgca gatgatataa tgcccacttg tgctcttatg 550

 aagttaactg ttcacagatg ccagccttga tcctgatgag ctatgcactc 600

 taatgtgggg ccactcacca gtcagccaat cttttattgt tcctttgcta 650

 ctttgaaagg aaaaaaaagg ttgtctcttg atttctgtaa ttcttctgct 700

 gatctgtgag tagggcactg ccctgctccc aatcaaactt agtcttttta 750

 tgagaaacct ggaccttcca tgaatgttgc cagcaataaa gtgacttgtc 800

 ctaatctatg gattgagaac ttgaaaatgt agagtagaat ttataactat 850

 catatggatg tcatcctgtg actttgaagt acaaagtaga ataaattctg 900

 tattcatgga ttggatgctg agcattctta ctcattaatt taggtggcta 950

 ggaattaatg aaaaaatttt caagttaaaa tacaggttat aacagtataa 1000

 tattcttttc taagttttcc tttcagattt actgttatgt tggctttagt 1050

 gtaagacaag gtcactgtgc tgattgattt ttatctaaaa aaattcattt 1100

 ttatatcgaa gaaaaaatat tttattcaaa cattagattt gaaagagtaa 1150

 tagtttataa aataaggaag taacatgtga ggctctcccc tcctcccctc 1200

 ccccatcata aagatatttt gaaatcccaa ggtgccctca tacctcttga 1250

 cattaatgac ttcatttttt agcttgaatt tgttagcaaa tattaatggc 1300

 agaaaaccaa aaactaaatt tatggtatcg agagcaccac cttctctttt 1350

 tgcccatatt gcactttgat ttcaaactat gcactgtgaa gagatttttt 1400

 tccccaggta ggaagggatg ttccctgtta tcgttatttt actgagctgt 1450

 ggaaactcat ttttaccctt tttaaagtca taaatatgga cttaatagcc 1500

 cttaaccttc aagtccaagc agttccaatc aggctgactt aggatcatgc 1550

 tggaaggaag ccaagtctca agaactgtca gcaacagaaa atgagatatg 1600

 atgctagaga gcatttgtcc ttgactgtaa gtacagaggc ttaggggaag 1650

 tgagacataa gcttgtagga ataataaacg ttctacaata aacgttttgg 1700

 ctatcttaag ccattgtatg ggggggatta ggaagtagga gggattgtcc 1750

 tacaacaggc ccttatactt caacagccca aatattttgg tttattcctt 1800

 tttatccata aagtctttat tcttcaagtt tgggtattat agattaccat 1850

 tgttagcctc ccttaatggg accatatgag ccaggctttt aagacggact 1900

 cattttgaat tgagtttcaa actttgaaag tgcaaggatt taatttttaa 1950

 gttgaatccc atgaaaggtg tcatcatcac taggaataac accctttgta 2000

 actacatata gaactgttac aatggtagca gaaaatccta ttgatttcat 2050

 ctcacccatt tcagatacct tcagtgaaat taagggtagt gtgatgtccc 2100

 atgtaataaa acaggcttag aacatcaatt cctctgctgc catttatgtg 2150

 cttttattcc cccttcaaaa attttttatt ggatatatat atttttcagt 2200

 attcagactc tgaaatctgt cattacaatc aagtgcttgt cacagctgaa 2250

 agatttctgg tggcttaaag tttactagca gtaaatttat gatatggtac 2300

 agttctttgt acagaaaggc accattatgt tagaataaat ttccagaact 2350

 tagtgggaag aatcaggttt taaccttgtg tgtctgttac ttctgagtgc 2400

 atttctataa tataaatgtt gatttgcgtc aacattataa aagagcactt 2450

 ctgtggctca tttaaaagaa aaaaaaaggt taagtctttt aaattttggc 2500

 cttgtttcca aatcctgtct tccatgttgt ttttctgcac ttcctgacca 2550

 ctcttataaa aagctcacaa acctttgaag aaactggagt aggctgttat 2600

 ttcattaagg tttacaaatt aaatgcttga tttttaatgt attctctact 2650

 gttttgattt ttggattttc ttaattcaac atttgaagat gtgccttttg 2700

 ggtaatgtta atcacgaatg tagtaatatt tcatgattgt aataatgtta 2750

 catgatcatg ggtgtggcat tctctaacaa atgatgtgaa aggaaagtag 2800

 ttttcataaa actcatggct ctgattgcac agtcccactt gcttttgata 2850

 ttgctatgtc aaagcaaagg gcacttcttt taaggctact ttcagaactt 2900

 tgtattttcg ctaaactata aatgcagttg tgtccagttg gaggccaggg 2950

 taccacatgt cacaggcggc cttacatgtg tgccgtgaaa aggttcaaag 3000

 accgttaaca aaaaagtaag tctggccggg catggtggct caagcctgta 3050

 atcccagcta ccggggaggc tgaggcagga gaatcgctag aacctgggag 3100

 gcggaggttg cagtcagcca agatagcacc actgcactcc aggctgggtg 3150

 acagagcgag actccatgtc aaaaaaaaaa gaatgtggga actcaaattt 3200

 tcatttttaa tgtaatcccc aagattttct ccaagaaata aattgttgtt 3250

 ttgtattttg taacttaaaa gcagctattg gtaaatttct gagatatagc 3300

 aggagaccaa aacatgtttg gaaagagaat aaatatatga agagagactg 3350

 gttgttttat tttcaatgta ttgaatatat tagactacta tttattttct 3400

 gagtggatgt gattaaatat tcagacgttt agtgtatgat taagagtgag 3450

 atagagattt ctttggagta attaaatcca tcctgtcttt tacacaatgg 3500

 acaaatcaag ttaaaaaaat ttttagatag cttagcttgt tttctggtgc 3550

 tgttgacctg caagagaata tacttttgca tatacaggtg aaagttttgc 3600

 aatttatgta tacaagaaat tgtaggcatt aaaaatattt tattgataaa 3650

 aaaaaaaaaa aaaaaa 3666

<210> 4745
<211> 2356
<212> DNA
<213> Homo sapien

<400> 4745
 atccacagta ggcattttaa taggacagat aatactgaag gggtaagcaa 50

 accagatgga tttcaagaac atgttacagc tactcacaaa acttacagat 100

 gtaatgattt ggtagagttg gcagtaggct tgagtcatgg agatcacagc 150

 agcatgaagt tagtagaaga agcagtacag ctgcaatatc agaatgcttg 200

 tgtgcaacaa ggcaactgta caaaaccatt tatgtttgac atttcaagaa 250

 ttttcacttg ctgtctacca ggcttacctg aaacttcttc ttgtgtttgt 300

 ccaggatata tcactgttgt gtcagtatct aataatcctg tgatcaagga 350

 attgcagaat cagcctgtgc gaatagttct cattgagggt gacctcacag 400

 agaattaccg ccacctggga tttaataagt ctgcaaatat taaaacagta 450

 ttagatagca tgcggcttca agaagacagc tcagaagaac tgtgggcaaa 500

 tcacgtgtta caggtgttaa tccagttcaa ggtgaacctt gtcctggtac 550

 aaggaaatgt gtccgaacgc ttaattgaaa aatgtataaa cagtaagcgg 600

 ttggtaatcg gctcagtgaa tggcagtgtg atgcaggctt ttgcagaggc 650

 tgcaggagca gtacaggtgg cctacattac acaagtgaat gaagattgtg 700

 tgggcgacgg ggtctgcgtg accttctgga gaagcagccc tttggatgtt 750

 gtagatagga acaacagaat cgcaatctta ttaaaaacag aaggaattaa 800

 tttggttacg gccgtgctca ctaacccagt tactgcacag atgcaaatca 850

 aagaagatag gttctggaca tgtgcctatc gtttgtatta tgctctaaaa 900

 gaggaaaagg tcttccttgg aggtggtgca gttgaatttt tgtgtcttag 950

 ctgtcttcat attcttgcag agcaatctct gaaaaaagaa aaccatgcct 1000

 gctcagggtg gctgcataat acttcctctt ggctggcttc atctctggca 1050

 atatacagac caactgtgct taaattcctg gcaaatggat ggcagagata 1100

 cctttcaact ctcctatata acactgccaa ttactcatca gaatttgaag 1150

 ccagcacata cattcaacat catctgcaaa atgccacaga ctctggctct 1200

 ccttcatctt acatcttgaa tgaatatagt aaactaaata gtagaatttt 1250

 taattcagac atttcaaata aactggagca gattccgaga gtttatgacg 1300

 ttgttacacc aaagattgag gcgtggcgcc gagcattgga tttagtattg 1350

 ttagtacttc agacagacag tgaaataatt actggacatg gacacacaca 1400

 gataaattca caggaattaa cgggctttct atttttgtag tgttactggc 1450

 taagtctttg gaaaataatt tttcataata tgtcatgcta ataataaata 1500

 tattgatagc caagtcatgg tgcctaaaat gccagctatt gccaagaaga 1550

 aaatagttga tgtctgtcaa taactgtgca tggtctgaga ttttacccta 1600

 cttataagct aacaagttag cctgttactg tttcgtggga tgctacagaa 1650

 tgcataagac acctgggtca gaaacaaagg acttatcgct cacagcaaaa 1700

 gctgtagcca gagcttcatg ttggttttat tcagttcctc atttttctag 1750

 ttcccacagg aggaacacaa agggcccatg atgaaagcct gcacacagtg 1800

 ggttatgttg taagcttggg ttattaactg cttttatagt aagcaaaaaa 1850

 tcctggtctt tgtccaaagg gagttattac cccatacttg aagatagctt 1900

 agtgtaaaca caagcctagg acatggacta ggtaaagaca aagtccttgc 1950

 attcttgaca tacccagtaa gtatgcaggg acactcagag cccatagtgg 2000

 atagtctctt ccaacagtct gctcctcagc ctgagatgtt cttggccaaa 2050

 cttgaatttt cacatgagta tgccactcta tcagctactc tgattaacct 2100

 gacagtcggg ttgtttagtc agtaccaaat ttgttcattt ggtctcatat 2150

 agcaattaat gcaggctatt atcagacaca gcagcaggat gaagccaacc 2200

 tgcagtatta acctcagtcc cgtcccccaa ggtcttgact caatcaactc 2250

 taagttccaa gggaggacca ataggtcttt ttattaggca gccagaatgt 2300

 agtgaaggac aatttattat actttatgac ccaataaagg gagctttgac 2350

 tgacgt 2356

<210> 4746
<211> 428
<212> PRT
<213> Homo sapien

<400> 4746
 Met Lys Leu Val Glu Glu Ala Val Gln Leu Gln Tyr Gln Asn Ala
   1               5                  10                  15

 Cys Val Gln Gln Gly Asn Cys Thr Lys Pro Phe Met Phe Asp Ile
                  20                  25                  30

 Ser Arg Ile Phe Thr Cys Cys Leu Pro Gly Leu Pro Glu Thr Ser
                  35                  40                  45

 Ser Cys Val Cys Pro Gly Tyr Ile Thr Val Val Ser Val Ser Asn
                  50                  55                  60

 Asn Pro Val Ile Lys Glu Leu Gln Asn Gln Pro Val Arg Ile Val
                  65                  70                  75

 Leu Ile Glu Gly Asp Leu Thr Glu Asn Tyr Arg His Leu Gly Phe
                  80                  85                  90

 Asn Lys Ser Ala Asn Ile Lys Thr Val Leu Asp Ser Met Arg Leu
                  95                 100                 105

 Gln Glu Asp Ser Ser Glu Glu Leu Trp Ala Asn His Val Leu Gln
                 110                 115                 120

 Val Leu Ile Gln Phe Lys Val Asn Leu Val Leu Val Gln Gly Asn
                 125                 130                 135

 Val Ser Glu Arg Leu Ile Glu Lys Cys Ile Asn Ser Lys Arg Leu
                 140                 145                 150

 Val Ile Gly Ser Val Asn Gly Ser Val Met Gln Ala Phe Ala Glu
                 155                 160                 165

 Ala Ala Gly Ala Val Gln Val Ala Tyr Ile Thr Gln Val Asn Glu
                 170                 175                 180

 Asp Cys Val Gly Asp Gly Val Cys Val Thr Phe Trp Arg Ser Ser
                 185                 190                 195

 Pro Leu Asp Val Val Asp Arg Asn Asn Arg Ile Ala Ile Leu Leu
                 200                 205                 210

 Lys Thr Glu Gly Ile Asn Leu Val Thr Ala Val Leu Thr Asn Pro
                 215                 220                 225

 Val Thr Ala Gln Met Gln Ile Lys Glu Asp Arg Phe Trp Thr Cys
                 230                 235                 240

 Ala Tyr Arg Leu Tyr Tyr Ala Leu Lys Glu Glu Lys Val Phe Leu
                 245                 250                 255

 Gly Gly Gly Ala Val Glu Phe Leu Cys Leu Ser Cys Leu His Ile
                 260                 265                 270

 Leu Ala Glu Gln Ser Leu Lys Lys Glu Asn His Ala Cys Ser Gly
                 275                 280                 285

 Trp Leu His Asn Thr Ser Ser Trp Leu Ala Ser Ser Leu Ala Ile
                 290                 295                 300

 Tyr Arg Pro Thr Val Leu Lys Phe Leu Ala Asn Gly Trp Gln Arg
                 305                 310                 315

 Tyr Leu Ser Thr Leu Leu Tyr Asn Thr Ala Asn Tyr Ser Ser Glu
                 320                 325                 330

 Phe Glu Ala Ser Thr Tyr Ile Gln His His Leu Gln Asn Ala Thr
                 335                 340                 345

 Asp Ser Gly Ser Pro Ser Ser Tyr Ile Leu Asn Glu Tyr Ser Lys
                 350                 355                 360

 Leu Asn Ser Arg Ile Phe Asn Ser Asp Ile Ser Asn Lys Leu Glu
                 365                 370                 375

 Gln Ile Pro Arg Val Tyr Asp Val Val Thr Pro Lys Ile Glu Ala
                 380                 385                 390

 Trp Arg Arg Ala Leu Asp Leu Val Leu Leu Val Leu Gln Thr Asp
                 395                 400                 405

 Ser Glu Ile Ile Thr Gly His Gly His Thr Gln Ile Asn Ser Gln
                 410                 415                 420

 Glu Leu Thr Gly Phe Leu Phe Leu
                 425

<210> 4747
<211> 1114
<212> DNA
<213> Homo sapien

<400> 4747
 cagatattcc catttatgtt ggaaacacag aaaggcctgt attttggact 50

 ctgaatcaga gcggtgtcca gttgactaat atcaatgtcg tgccatttgg 100

 aatatggcag caggtggaca aaaatcttcg attcatgatc ttgatggacg 150

 gtgttcatcc tgagatggac acttgcatta ttgtggagta caaaggtcat 200

 aaaatactca atatagtaga ctgcaccaga cccaatgggg gaaggctgcc 250

 tatgaaggtt gctaatgatg agtgattttg ctggaggagc atcaggcttt 300

 ccaatgactt tcagtggtgg aaaatttacg gcagaggaga ctccaatcta 350

 aatcctgtca tttcagagga atggaaagcc caattcatta aaacagaaag 400

 gaagaagctc ctgaactaca aggctcggct ggtgaagaac ctgcaacccc 450

 gaatttattg tccctttgct gggtattttg tggaatctca cccatcagac 500

 aagtatggct agacactttg tacattttta catacaactt aacgtatggt 550

 ggaatgagcg actttgctgt gaaagcagtg tgacatgaga aggaaagtga 600

 ttagtaggtg tctggaactt tttaacaagc tgctggagaa cccagagcat 650

 gaataaaagt tacacttggc agccaggaac tctttcagaa gataaaataa 700

 cagatagata ttctccgaaa ggatcccagg aaagaggatg gcaactgcca 750

 tttattatgt gaagtgaact ggggactttt aactaagcca tctaagttaa 800

 tctcccaata gcactatgcg taggaagggg gtattgttcc ttttttgcag 850

 ataaggaatc tgaaactcag aaaggtcaag ggacgtgccc aaagtcaccc 900

 tgttggaaac atgagttgag aatggaaccc tggtatgctt agttctaaag 950

 ctcttttctc tataccatac tgcattccag aatagaatta tgtctttctt 1000

 ctcatgtttt aggtatctaa tgtgattttt cttgcagcaa tataacttct 1050

 gcaaatacta tgaatcatca ccaatgtatg aaattgttga aagaaataaa 1100

 agaccatgaa tttg 1114

<210> 4748
<211> 90
<212> PRT
<213> Homo sapien

<400> 4748
 Asp Ile Pro Ile Tyr Val Gly Asn Thr Glu Arg Pro Val Phe Trp
   1               5                  10                  15

 Thr Leu Asn Gln Ser Gly Val Gln Leu Thr Asn Ile Asn Val Val
                  20                  25                  30

 Pro Phe Gly Ile Trp Gln Gln Val Asp Lys Asn Leu Arg Phe Met
                  35                  40                  45

 Ile Leu Met Asp Gly Val His Pro Glu Met Asp Thr Cys Ile Ile
                  50                  55                  60

 Val Glu Tyr Lys Gly His Lys Ile Leu Asn Ile Val Asp Cys Thr
                  65                  70                  75

 Arg Pro Asn Gly Gly Arg Leu Pro Met Lys Val Ala Asn Asp Glu
                  80                  85                  90

<210> 4749
<211> 3307
<212> DNA
<213> Homo sapien

<400> 4749
 cgcggcggcg gcggcggcgg cggcggcgtt gagtgtctgg cccgccggtc 50

 cggtcggggt gtgcagtcgg acggacgagc agcgcgtcgc tgtcctccgg 100

 cagctggaga tgtccgagcc caaggcaatt gatcccaagt tgtcgacgac 150

 cgacagggtg gtgaaagctg ttccatttcc tccaagtcac cggcttacag 200

 caaaagaagt gtttgataat gatggaaaac ctcgtgtgga tatcttaaag 250

 gcgcatctta tgaaggaggg aaggctggaa gagagtgttg cattgagaat 300

 aataacagag ggtgcatcaa ttcttcgaca ggaaaaaaat ttgctggata 350

 ttgatgcgcc agtcactgtt tgtggggaca ttcatggaca attctttgat 400

 ttgatgaagc tctttgaagt cgggggatct cctgccaaca ctcgctacct 450

 cttcttaggg gactatgttg acagagggta cttcagtatt gaatgtgtgc 500

 tgtatttgtg ggccttgaaa attctctacc ccaaaacact gtttttactt 550

 cgtggaaatc atgaatgtag acatctaaca gagtatttca catttaaaca 600

 agaatgtaaa ataaagtatt cagaacgcgt atatgatgcc tgtatggatg 650

 cctttgactg ccttcccctg gctgccctga tgaaccaaca gttcctgtgt 700

 gtgcatggtg gtttgtctcc agagattaac actttagatg atatcagaaa 750

 attagaccga ttcaaagaac cacctgcata tggacctatg tgtgatatcc 800

 tgtggtcaga ccccctggaa gattttggaa atgagaagac tcaggaacat 850

 ttcactcaca acacagtcag ggggtgttca tacttctaca gttacccggc 900

 tgtatgtgaa ttcttacagc acaataactt gttatctata ctccgagccc 950

 acgaagccca agatgcaggg taccgcatgt acaggaaaag ccaaacaaca 1000

 ggcttccctt ctctaattac aattttttca gcaccaaatt acttagatgt 1050

 atacaataac aaagctgcag tattgaagta tgagaacaat gttatgaata 1100

 tcaggcaatt caactgttct cctcatccat actggcttcc aaatttcatg 1150

 gatgttttta cttggtccct tccatttgtt ggggaaaaag tgactgagat 1200

 gctggtaaat gtcctcaaca tctgctcaga tgatgaacta gggtcagaag 1250

 aagatggatt tgatggtgca acagctgcag cccggaaaga ggtgataagg 1300

 aacaagatcc gagcaatagg caaaatggcc agagtgttct cagtgctcag 1350

 agaagagagt gagagtgtgc tgacgctgaa aggcttgacc ccaactggca 1400

 tgctccccag cggagtactt tctggaggga agcaaaccct gcaaagcgct 1450

 atcaaaggat tttcaccaca acataagatc actagcttcg aggaagccaa 1500

 gggcttagac cgaattaatg agaggatgcc gcctcgcaga gatgccatgc 1550

 cctctgacgc caaccttaac tccatcaaca aggctctcac ctcagagact 1600

 aacggcacgg acagcaatgg cagtaatagc agcaatattc agtgaccact 1650

 tcctgttcac tttttttttt tttttttttt tttttttttg agctgcgggg 1700

 catgatgggg attgctgcat atcagcagtt ggatgttctt gcctctgaca 1750

 gtagcttatt tgctctgggg gccaggaatt ggattcagtt tacactatca 1800

 ttaaaaaaga gggagagaga taataaacta tattttggtg gggatggtga 1850

 ttaaacacct cttttgggta tgccttttaa aaatgcttat agagaaaaaa 1900

 aattttaaaa agaaagctaa tgctagtata tactgcaatg ttaggggaat 1950

 gaacatgttt tcctactgca ttggggactt ctagataggt taatgaaagg 2000

 ccttttattc tgttactgga catgaaaact ttgtctaatt tcttactcta 2050

 ttgtacgttt acagtcgcag cactaaaaat ggatgacatc aaacattttt 2100

 aacaaaatga tgtacaaact aaggactatt tattgataat gttttgctac 2150

 tcttgtcaga caatggctat aaactgaatt aggcagtctt aaaaaaaaaa 2200

 aaaaacagaa aaagaaaaaa aagaacgttg caaatttgtt aaaatgccaa 2250

 aaaggacagt ttaattttgt acagattatg cttacctcag gtttctttag 2300

 tgtgcttgaa tgcccttctt tccatataac acttatcttc ttcttaattc 2350

 ggcaatggaa tatcttttaa gttttaaaaa aaactggaat aattatatct 2400

 atcttttttg ccgtttatat ttaggggttt ttgttgataa aatcaagtct 2450

 tggttgtggc ttgctgaatt aaatatttat gagtggtgca tttttaagta 2500

 tagtgaacaa gacaccatat taagtacagt gataaagcat ctatattctg 2550

 taaaaaaaaa aaaaaatctg cctatgcatg ttttttaaga aaaaaaaaat 2600

 ggctgtatcg gcctgtatgg gactgtaatg cgcttagtgg tctgacatat 2650

 actggaaatg tatgtatact ggcgtacttt atattctcta aaatgcttaa 2700

 tgcctttgaa attttgtaat caaaaaaaag ctttgaaaaa atctaaaggg 2750

 gagagtattc tttaaatttt ttaacataag cttgtcaatg cacatgtaga 2800

 tggttagcat gtttagcaaa ccttgtgaaa ttataataag tttgtagtta 2850

 catgtgaaac tctaaatgca tggcaactgt taatgtcata acagtttagt 2900

 tattttgttc tgttctgtca tgtgccacaa aatatgtact tttttcactt 2950

 ttttcccttt gtatatcagt tacgggttac aactggttca ttctgaaaac 3000

 aacaacaaca aaagtccatt catatttttt aacaattgta taagtgccca 3050

 agtaattcac tacagcctaa agccttgcct ttgtaatttg acttctgaca 3100

 tgttggcaat caaagcatgc acttgtaaca atgaaaaaga aaaagcattt 3150

 tatattacta ctcaataaaa tgtgcatgaa cttaaaaaaa aaaaaaaaaa 3200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3250

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3300

 aaaaaaa 3307

<210> 4750
<211> 511
<212> PRT
<213> Homo sapien

<400> 4750
 Met Ser Glu Pro Lys Ala Ile Asp Pro Lys Leu Ser Thr Thr Asp
   1               5                  10                  15

 Arg Val Val Lys Ala Val Pro Phe Pro Pro Ser His Arg Leu Thr
                  20                  25                  30

 Ala Lys Glu Val Phe Asp Asn Asp Gly Lys Pro Arg Val Asp Ile
                  35                  40                  45

 Leu Lys Ala His Leu Met Lys Glu Gly Arg Leu Glu Glu Ser Val
                  50                  55                  60

 Ala Leu Arg Ile Ile Thr Glu Gly Ala Ser Ile Leu Arg Gln Glu
                  65                  70                  75

 Lys Asn Leu Leu Asp Ile Asp Ala Pro Val Thr Val Cys Gly Asp
                  80                  85                  90

 Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu Val Gly
                  95                 100                 105

 Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr Val
                 110                 115                 120

 Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Ala
                 125                 130                 135

 Leu Lys Ile Leu Tyr Pro Lys Thr Leu Phe Leu Leu Arg Gly Asn
                 140                 145                 150

 His Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu
                 155                 160                 165

 Cys Lys Ile Lys Tyr Ser Glu Arg Val Tyr Asp Ala Cys Met Asp
                 170                 175                 180

 Ala Phe Asp Cys Leu Pro Leu Ala Ala Leu Met Asn Gln Gln Phe
                 185                 190                 195

 Leu Cys Val His Gly Gly Leu Ser Pro Glu Ile Asn Thr Leu Asp
                 200                 205                 210

 Asp Ile Arg Lys Leu Asp Arg Phe Lys Glu Pro Pro Ala Tyr Gly
                 215                 220                 225

 Pro Met Cys Asp Ile Leu Trp Ser Asp Pro Leu Glu Asp Phe Gly
                 230                 235                 240

 Asn Glu Lys Thr Gln Glu His Phe Thr His Asn Thr Val Arg Gly
                 245                 250                 255

 Cys Ser Tyr Phe Tyr Ser Tyr Pro Ala Val Cys Glu Phe Leu Gln
                 260                 265                 270

 His Asn Asn Leu Leu Ser Ile Leu Arg Ala His Glu Ala Gln Asp
                 275                 280                 285

 Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln Thr Thr Gly Phe Pro
                 290                 295                 300

 Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr Leu Asp Val Tyr
                 305                 310                 315

 Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn Val Met Asn
                 320                 325                 330

 Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu Pro Asn
                 335                 340                 345

 Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu Lys
                 350                 355                 360

 Val Thr Glu Met Leu Val Asn Val Leu Asn Ile Cys Ser Asp Asp
                 365                 370                 375

 Glu Leu Gly Ser Glu Glu Asp Gly Phe Asp Gly Ala Thr Ala Ala
                 380                 385                 390

 Ala Arg Lys Glu Val Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys
                 395                 400                 405

 Met Ala Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val
                 410                 415                 420

 Leu Thr Leu Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly
                 425                 430                 435

 Val Leu Ser Gly Gly Lys Gln Thr Leu Gln Ser Ala Ile Lys Gly
                 440                 445                 450

 Phe Ser Pro Gln His Lys Ile Thr Ser Phe Glu Glu Ala Lys Gly
                 455                 460                 465

 Leu Asp Arg Ile Asn Glu Arg Met Pro Pro Arg Arg Asp Ala Met
                 470                 475                 480

 Pro Ser Asp Ala Asn Leu Asn Ser Ile Asn Lys Ala Leu Thr Ser
                 485                 490                 495

 Glu Thr Asn Gly Thr Asp Ser Asn Gly Ser Asn Ser Ser Asn Ile
                 500                 505                 510

 Gln


<210> 4751
<211> 979
<212> DNA
<213> Homo sapien

<400> 4751
 tgctctccca ggcagcaacc tgatcaattc attcacacca tggtgctaat 50

 agctaatgtt aggttcatat taatttaccc aggaatatct gaattccagg 100

 ctttaggact aggcattaaa ccaaagtggt gactttcaat ggagggctaa 150

 tacatactga agcagacaga ctggagggaa agaaattttg gataaagtgg 200

 gtcccacagc actgcctttc atattgcata cagtaagcaa acacctactt 250

 tggttaccat aatgggaatg ctgactttta agaaattaag aaatgtatcc 300

 atgaacatgg ctatcagttt ctcagatgtc tgctcacctt cttttcattt 350

 tgcctctctc ctttcctacg ttgggcctga ttttcagggg aaagtctaaa 400

 ctagtagctt actaatttag gagtactggt gcagctacga tccagacagc 450

 agcctgttct ctgagcttct ccattccatg gcttatccag acttctcatt 500

 tatcactctc tgggttctat gaaattgtgg tgcaaagagt aaacaccctc 550

 aaccatagta atgtatactt caagataaat aattccacat ttcctatata 600

 aagttgttga attttgattc aaaaatgcgt aagtattcca ataagaaaaa 650

 ctttgtatgt agtgatttct atgtaaaaat attgtaatta ttattatatt 700

 caaatggttt atatgttttc attgtcactc agttaagcag ccaattctgt 750

 tagctggtaa ttccacaaag agaagccatc tgccccagga gcaacagacc 800

 aagctgcctt ggtctgagag ggtgcatctg tggaactctt gcgcaactta 850

 cattttatgt caccttttga ttttactccc aagatactgt gaaaatgttg 900

 cacttggaat ttatttatgg ctataactta taatattcat tttaataata 950

 aagattgtct ttgtaattac atagaaaaa 979

<210> 4752
<211> 43
<212> PRT
<213> Homo sapien

<400> 4752
 Cys Ser Pro Arg Gln Gln Pro Asp Gln Phe Ile His Thr Met Val
   1               5                  10                  15

 Leu Ile Ala Asn Val Arg Phe Ile Leu Ile Tyr Pro Gly Ile Ser
                  20                  25                  30

 Glu Phe Gln Ala Leu Gly Leu Gly Ile Lys Pro Lys Trp
                  35                  40

<210> 4753
<211> 1022
<212> DNA
<213> Homo sapien

<400> 4753
 ggaccggcca ctaccggtcc tgagtctggc tccagcgcca ccaccagtgg 50

 ccgtggcctc gccgtctgcc gtcgcccccc gtgagcctgg acccctgcgc 100

 tcccgcacca gcccccgcct ccgccctgca gaagcccaag atctggtccc 150

 tcgcggagac tgccacaagc ccggacaacc cgcgccgctc gcctcccggc 200

 gcgggggggt ctccaccggg ggcagcggtc gcgccttccg ccctgcagct 250

 ctctccggcc gccgccgccg ccgccgctca cagactggtc tcagcgccgc 300

 tgggcaagtt cccggcttgg accaaccggc cgtttccagg cccaccgccc 350

 ggcccccgcc cgcacccgct ctccctgctg ggctctgccc ctccgcacct 400

 gctgggactt cccggagccg cgggccaccc ggctgccgcc gccgccttcg 450

 ctcggccagc ggagcccgaa ggcggaacag atcgctgtag tgccttggaa 500

 gtggagaaaa agttactcaa gacagctttc cagcccgtgc ccaggcggcc 550

 ccagaaccat ctggacgccg ccctggtctt atcggctctc tcctcatcct 600

 agttctttaa aaaaaaacaa aaaaacaaaa aaaacttttt ttaatcgttg 650

 taataattgt ataaaaaaaa tcgctctgta tagttacaac ttgtaagcat 700

 gtccgtgtat aaatacctaa aagcaaaact aaacaaagaa agtaagaaaa 750

 agaaataaaa ccagtcctcc tcagccctcc ccaagtcgct tctgtggcac 800

 cccgcattcg ctgtgaggtt tgtttgtccg gttgattttg gggggtggag 850

 tttcagtgag aataaacgtg tctgcctttg tgtgtgtgta tatatacaga 900

 gaaatgtaca tatgtgtgaa ccaaattgta cgagaaagta tctatttttg 950

 gctaaataaa tgagctgctg ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1000

 aaaaaaaaaa aaaaaaaaaa aa 1022

<210> 4754
<211> 2580
<212> DNA
<213> Homo sapien

<400> 4754
 agctgggctg tcacccccga gctccttaga cactcctcac acctgtccat 50

 acccgagggt ggatattcaa ccagccccac cgcctacccg actcggtttc 100

 tggatatcct ccgtgggcga actgcgagcc ccattcccag ctcttctccc 150

 tgctgacatc gtcccttagt tgtggttctg gccttctcca ttctcctcca 200

 ggggttctgg tctccgtagc ccggtgcacg ccgaaatttc tgtttatttc 250

 actcaggggc actgtggttg ctgtggttgg aattcttctt tcagaggagc 300

 gcctggggct cctgcaagtc agctactctc cgtgcccact tccccccaca 350

 cacacacccc accctgttgc tgaccaaggt gatttttggc acatttgttc 400

 tggcctggct tggtgggacc ccacccctat tctgcttctg tgagtccctg 450

 atagagaagg aggtcccatc aggcccctgg aacacactca ggcttccgtg 500

 actcaggaca aggaccacgg gaggcccagg tgcggaaagg aggctccgtg 550

 agatggggtc cagcccatcc caacacaagg gtgcagcttg attcgggagt 600

 tccccacctc ctgcccattc tccgcgtcct tttaccccat ggagagcctc 650

 agccatggca agtccatctg gagtccagga agcaggcaac tggcctgacc 700

 catgagaccg tttggagacc aagcagcaga tgcaggtgtg gaccccagga 750

 acctacaggg gtgtcagccg ctgagccccc tccctgctgt gtgggtggtg 800

 agcaggctgg gtctttgtct gtcttcttct acacggcatg tgcctgcacc 850

 agccccaaca cctgagctgg tttagcgcaa agaagagctc tgactctcca 900

 ggggtgctgg gacatcacgt ggaattggat cccaggctct cttgggcgag 950

 aaagaccatt ctggaggtgg gagtgggaga gctgcctgtc tgcccacggg 1000

 ctctgcgtct ccgcagtggg tggccttgga tgcccggccc ctccctttct 1050

 gtgcactggg gacgctgatg gaggctgaag ctgctgttcg gaggccctct 1100

 attggtgcct ctctcctgcc gtcatcacta tggcaggaaa acagagatgg 1150

 tttagtaatg aattatcatt cccaaacccg tgtccacctg gaacatcagg 1200

 atgggaccat gtttgaaaat cgggtctttc caaatgtaat taagtaaggc 1250

 gaggccatac tgcatttaca atgggcccaa tccagtgtcc ctatgagaga 1300

 cggaagagga gacacagaca caaagcagga ggccacataa agacagaggc 1350

 agagactgaa gtgatgctgc cccaagccca gggatgcctg gagtccccag 1400

 gagctgggag aggcaggaag gaccctcccc tagagtctct ggagggaact 1450

 ggatacaatt gcagagtgca ctaaacagtt gccccagaaa gacatgtctt 1500

 gttttaaagc ccagaacctg aaattattat agattttatt cggtaataag 1550

 gaactttgca tgtgtaatta cttaaggata tgaagatgag attgtgctgg 1600

 attattaagc accctaaatg ccatgacagg tgtccttcca agagacagaa 1650

 gaggagacac agacacagag caggaggaca cgtggagaca gaggcagact 1700

 ggagtgatgc ggccacaagc ccagggacac ctggagcccc caggagctgg 1750

 gagaggcagg aaggatcctc ccctagagcc tccaggggga actggaggat 1800

 gcgtaagaga cccagaactt ccacagaagg aggaaaatta acctcctgct 1850

 tctctagact gttccaaagc tgaaccctag aaagcaaagc tgatacagaa 1900

 gcatccaggc tgcaggagta caggtcgcaa gtgctgagcg tgggccttgg 1950

 gtgtgtctca tgggggaaaa aaaactgtga aaaacctcag agtagcatct 2000

 tcacagtaac gcacggacga tccctaaact gccttgtaaa caaaaatgag 2050

 agcttgagtc agaggaagcc gagacaatat ccttcctcga caacgtgcga 2100

 gaaccctgac gtcccccagc aaaggaagac gttgcaagca ggcaaaatgc 2150

 gtcgattttt ttttttgtca gtatgatgat ttttgcagcc acttggctat 2200

 tgagagcagc cgacaccccc tcttacagcc gtggatgttt cctggaaact 2250

 gactcagtct gttcactggt tgagctttga gtgaaaagat aacacaggtc 2300

 tattgactca cacacatgtt ttaagatgga aaactttact tctgttcttg 2350

 gcaggacatg gagagaggga gggattccaa aaagtctcag cctccatcaa 2400

 ggcgtggcag ctcatgccgg taatctcagc actttgggag gctcaggcgg 2450

 gaggactgat tgagtccggg tgttcaaggg ccaacctagg caacacagtg 2500

 agaactcatc tctgtaaaaa ataaaaataa aacattaaaa aaaacatgaa 2550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2580

<210> 4755
<211> 97
<212> PRT
<213> Homo sapien

<400> 4755
 Met Lys Met Arg Leu Cys Trp Ile Ile Lys His Pro Lys Cys His
   1               5                  10                  15

 Asp Arg Cys Pro Ser Lys Arg Gln Lys Arg Arg His Arg His Arg
                  20                  25                  30

 Ala Gly Gly His Val Glu Thr Glu Ala Asp Trp Ser Asp Ala Ala
                  35                  40                  45

 Thr Ser Pro Gly Thr Pro Gly Ala Pro Arg Ser Trp Glu Arg Gln
                  50                  55                  60

 Glu Gly Ser Ser Pro Arg Ala Ser Arg Gly Asn Trp Arg Met Arg
                  65                  70                  75

 Lys Arg Pro Arg Thr Ser Thr Glu Gly Gly Lys Leu Thr Ser Cys
                  80                  85                  90

 Phe Ser Arg Leu Phe Gln Ser
                  95

<210> 4756
<211> 1616
<212> DNA
<213> Homo sapien

<400> 4756
 ggttccttct tttggccact taaaatatct tatatttcta gatttccagg 50

 tctatgtgga aatcatcaca ctggggccaa taaatgggtt agttcagatg 100

 tgctgagaaa agtaaatagt gtaccctaaa tatcttgcat gtacatttat 150

 ctatttctct gtttaatgcc acttaatttt gtaagaaatg agaaatgaaa 200

 ccctatgtat cagtggaaaa atccttcttg cttcagattt cccaacttta 250

 ttctggagga gaaaaaaatc tgtatttctc attaacagag atagaaaaag 300

 gtgatgtact tacgatggtc acattcatat tgggcattgg atctatttaa 350

 gcctagaagt ataacagata atcagttcct taagtgtaaa tatgttctta 400

 aatgtttggc ctttttatct gttattcaaa tgtattagta attctcatat 450

 tttgcaaaca gatccttttg tgtatattat aaaatatata ccaaatctgt 500

 ttttcctttt gctgtggaag atgtctttat ataatattga gacttccctt 550

 gcaaatgaga gacgggactc tggtcaggta tagtgtgtag gcctagcccc 600

 atgtattagg aactcataaa ctcagaaatc caaggattaa acattttatg 650

 tctccttcat ttatgcaagt catgctttca ttctacatgt agttaaaact 700

 acaagtatga gaaaaaatag aactttccat tggaattttt tccaatcagg 750

 taatgtttta gcaacttgaa atcagcactt aatttgattg tattacctat 800

 caaagaacca ataacctttc ctttttctgc agtaaagaaa atgaaatatc 850

 ctttattttc caaatgtatg aagcacaaat gcaatatagt tatttaaaat 900

 ataaaatact ttaaaatgaa tgtgaagaat gggaaaatat atttttgcat 950

 gaaaacagac tacttacaaa tgtgcttaat atctcaggaa aaaaagaatg 1000

 aataaccgta tataaaattg gtaaactata aattggctgt atttccttgc 1050

 cggttttaat tttaaggaag catttacatg aaaagaaaaa aggatcctag 1100

 tagtctgaat ttcctctcaa gtatgctaga aaatactttc tatgaattta 1150

 caattaactg caataagaag tgggttagca ttcaagtaag gtcaataccc 1200

 caaatgagaa actcttcagt tagaacacat tagtggttgt aacacagagg 1250

 cagtagataa atatttgaaa tgtgagcatt tctaaacttg gtaccaaatg 1300

 gaaagggttt catgaggtga cagtggcttt taaacattca tttgaccgat 1350

 tattctaatt ttccttgtta aatcattgca acagttgcat gggggagaat 1400

 ggatattttt tgaagaattg cttattccac tttcaatttt taaaaatcga 1450

 ggggattaaa atattacttt ttaaatatgc ataaaagtat cttaactgta 1500

 attacatttt cagttgcttt gttatagtag catgcatatt aaatataaaa 1550

 tgcatttatg aaaatttttg taaaaaataa aagattttct cgagccgggg 1600

 agaatccaaa tacaac 1616

<210> 4757
<211> 42
<212> PRT
<213> Homo sapien

<400> 4757
 Gly Ser Phe Phe Trp Pro Leu Lys Ile Ser Tyr Ile Ser Arg Phe
   1               5                  10                  15

 Pro Gly Leu Cys Gly Asn His His Thr Gly Ala Asn Lys Trp Val
                  20                  25                  30

 Ser Ser Asp Val Leu Arg Lys Val Asn Ser Val Pro
                  35                  40

<210> 4758
<211> 6014
<212> DNA
<213> Homo sapien

<400> 4758
 attatgggct gtgggtgccg ctgagcaaga tggagctgtc tgcagtgggc 50

 gagcgggtct tcgcggccga atccatcatc aaacggcgga tccgaaaggg 100

 acgcatcgag tacctggtga aatggaaggg gtgggcgatc aagtacagca 150

 cttgggagcc cgaggagaac atcctggact cgcggctcat tgcagccttc 200

 gaacaaaagg agagggagcg tgagctgtat gggcccaaga agaggggacc 250

 caaacccaaa actttcctcc tgaaggcgcg ggcccaggcc gaggccctcc 300

 gcatcagtga tgtgcatttc tctgtcaagc cgagcgccag tgcctcctcg 350

 cccaagctgc actccagcgc agccgtgcac cggctcaaga aggacatccg 400

 ccgctgccac cgtatgtccc gccgtcccct gccccgcccg gacccgcagg 450

 ggggcagccc cggactgcgc ccgcccattt cgcccttctc ggagacggtg 500

 cgcatcatca accgcaaggt gaagccgcgg gagcccaagc ggaaccgcat 550

 catcctgaac ctgaaggtga tcgacaaggg cgctggcggc gggggcgccg 600

 ggcagggggc cggggcgctg gcccgcccca aagtcccctc gcggaaccgc 650

 gttataggca agagcaagaa gttcagcgag agcgtcctgc gtacacagat 700

 ccgccacatg aagttcggcg cctttgcgct gtacaagcct ccgcccgccc 750

 ccctggtagc cccgtccccc ggcaaggctg aggcctcagc cccgggccct 800

 gggctacttc tggccgcccc cgccgccccc tacgacgccc gcagctctgg 850

 ctcctccggc tgcccctcgc ctacaccaca gtcctctgac cccgacgaca 900

 cgccccccaa gctcctcccc gagaccgtga gcccatccgc ccccagctgg 950

 cgcgagccgg aggtgctcga cctgtccctc cctcccgagt cggcagccac 1000

 cagcaagcgg gcaccgcctg aggtcacagc tgctgccggc ccggcacctc 1050

 ccacggcccc tgagcccgcc ggtgcctcct ccgagcccga ggctggggac 1100

 tggcgccccg agatgtcacc ctgctccaat gtggtcgtca ccgatgtcac 1150

 cagcaacctc ctgacggtca caatcaagga attctgcaac cctgaggatt 1200

 tcgagaaggt ggctgctggg gtagcaggcg ccgctggggg cggtggcagc 1250

 attggggcga gcaagtgagg gggctccacc aaggaggggg gcttgggggg 1300

 gccctcctgc ccgaagtcat actcttgctc ccaccccacc cttgccccca 1350

 gccctctctc cctgtgcttt gcttgtctca aatggctcgg tgttgaccca 1400

 gggatggggc tgggtagttg gggtcccaga aagccggggg taggggccac 1450

 cctggaatgg ggcaggggaa gggcacaccc cctgcccatg catggtagcc 1500

 cactgggtgg tttctggaaa gccctagaaa ctagggttcc tctgcccctt 1550

 ccacatccca cctgtctctc tagcttgctt cctgctctcc tgtgcggcgt 1600

 ctgatttctc ggtgctaacc tggcagctgt ggggccctta ggagcccccc 1650

 accgagggtg gacacagtcc ctttccttcc tgcagatgcc taggcaggag 1700

 gagggcttcc tgcctgtttg gcaaagtccc aggcagaggc caaggatgag 1750

 gcctgactcg gctcctccct ccacatcagc cagggcatca gaagttgggc 1800

 cagggcgggg tcttccctgc tcgattttgg acgaggccta agtagacccc 1850

 ctatgccctg ccccagccct ggctctttcc taaccccctc aacggtggga 1900

 ggaactggca gagggtgcgc ctggccacag cctccccgca tctaaaggcc 1950

 ccttcagttc ttgaccaaag gtgctacgag aacctgccgt ggaaacttcc 2000

 agttgtgcgt ctgccccact cgctgtgttt gtccgtgggt tcatacatgc 2050

 attgggtgct aggccccagg ctgccgggtg gcacccttta cagttccttt 2100

 gaacaggggc attgaaggcc tggactgcct ctcgcctcag taggcctggg 2150

 gaccaggctt gggtctggag gtttgctgtg gaagtcacca ggcctcccct 2200

 cctggcccag gtgtgctggg ggcaccgtgc cccccacccc cctgccctcc 2250

 tcagggtggt cagcccaacc tgtcggacct tcacttcaca tcatggtggg 2300

 gaccgagata gagagggaga ccccattcca agctccctct tcctccgggt 2350

 gtttggggag gatgctgaag aatccattcc cgagggcctc ccggcttgtc 2400

 ccagcccctc ttttgcttct gaccacggag gctttctcac agcccagcct 2450

 gcctgaagca aaggaggctc ccgtgtcctg ggcagcttct gtttccctct 2500

 gctgcctggg agctgaggca cccgtgccag tggcagaggc cacagcccca 2550

 gccttaggcc aggccctggg agggcaggca ggcaaagggg agaccagagg 2600

 gtctgtgttc tccaggagaa tgagggtgtt ggtcccagaa ttgggaccgg 2650

 ggccccgctg gccagccctg ggccacttcc cgggtctcca ttgtgcgtgg 2700

 gtggcgtgtt ccaggcgtgg ctggagctgg cttcctggct gtgctgccat 2750

 gggcccctcc ctcagaagca cgttggcagg aggccgatca gaaccctagc 2800

 gcctttggtc ctaagaatgg gaggctgcct tccttcccaa tctccctgcc 2850

 agggcccaca gcgtggccct agccctcccc tccccgggat gtagaacggg 2900

 gaccctcgca gggttggggc gggggctgat actcctcggc ccctccctac 2950

 cctgccctgt gtgttggctt tgtggccgtc caagtgccaa ttggcttttc 3000

 gcccaaataa gggctggtat ttctcctctg tccttggagg tgatttcccc 3050

 ctgaccccct cccccaggtg agtgaccacc tgggtgccag ttacaggtgt 3100

 ttccagagac catagaaatg tgttttcctg agagttcgtg tcattcgtga 3150

 cttttttgta aagaagttgt gttttcagag gtgattttat gacaggaaag 3200

 tgaaagaatt agttttgcaa aaaaacaaaa acaaaaaaag aggaaaaaaa 3250

 aaagaaatag aaaaaaatat tgtgggattc ctatgggggg gtggcggggg 3300

 agaaagagct atttaagaaa aaatagtaac gcagtgattg cacaggtgag 3350

 gtggcaatgt caggatgggg cggaggcctg ggcccagctg gcaggtcccc 3400

 tggcatcgca ggcactgtgg agagggcctg gacccagatc tccacacccg 3450

 tgcttgctca aagggaagga caacagcggg cccccgggag ctaacccaag 3500

 ctgcaggtcc cggcaagctg aggtttggga gggtgggggt tgtcactggt 3550

 gattttctcc agggggctgg tgagtgggca gtttggtttc ttgccccctt 3600

 ctgttccttt cccagttgtt gggccatctg gtccccacca ccgccaccct 3650

 atgggggaga cctccctccc cacgggtcac cctaaagccc acaacctctc 3700

 tgagcctccc tggcctgaaa ggggatgcag gcttcaggag gcaagaagct 3750

 gggcccctgg gggtggctgg ggagagggaa tgcatttccc ttgccacagg 3800

 tggtctgctt ctgctggcct gagctccaag tggagcagcc cgggccagcc 3850

 ttggtgcatg aagaggcacc aggcacaccg ccttgaggtg ggcagtgccc 3900

 atgggggccc gagtggatgg gaccgagggt gagtggagcc tccttcctcc 3950

 cctctctagt acccccgcct cccacacact tgcacggatc ggcctccctt 4000

 gggagatcag cctccatggg cccctcgtcc acccttgctg ctttccattt 4050

 gcctaattac caagcagaag ttgcaatctg gtttgcttta tttttgtatg 4100

 tgaaataacc cccaaagccc aatctcctcc tacgttcaat attggttggg 4150

 gcatccgtca tctcccctta agtgcgcccc ctccccaccc aagtatcata 4200

 ggaaaccggt gaggtctggt gtctctggtt tgagacggta agttgggacc 4250

 catccctgtc tgggtgccca ctctgacctt tagtttgccc ttctgtgaaa 4300

 tgggtgtatt gggtagcaag ccctcttcag aaagcgctgc tggtgtcaga 4350

 gcagctgccc agtaccaggt ggggggtcaa ggttgctggt actggggccc 4400

 ccagctgccc acaacccctc tttgttctca ccctgcaaag gggtcaaggt 4450

 caaaatgagc ctcatccttc ctatgatctg ggaagaggtg atgatcaagt 4500

 ccccaacttc agtgtgaggt ggacagagtt ggggggatgg cccctttttg 4550

 aagaggtgaa aatggttttg gagaagcgca gctgcttcac tgggggaatg 4600

 cggcagggac tggggcccag gatgctttgg cctatgggga aaagcccttt 4650

 aaaaggcagg gcccaggccc tggagccagc acaagactgg cctcgagccc 4700

 ctgagccagg aggtcctgga ggagagccag gccggtgggc ccgcccaagg 4750

 ctggagggtc agccccaaca gggagctggg ttggccaggg ggctggactg 4800

 ctaccagcct ctctggccta tggggaccca agaggacaca tccccctttt 4850

 gcccactctt ctgtgtcatt ttgttgtttt ggtttgtggt ggtttttctt 4900

 ttttcttttg tttttctttt ttctttcttt cttttttttt tttttttttt 4950

 ttttttttgc acttcgccca cacaggacag tggagcccca cctggtcagt 5000

 tccacttccg ggctcccatg cacttgccca aggcggcctc tttgggacgg 5050

 ggatggtttg aggaaacact tttaaagaaa aaaggaagac attgaaaggt 5100

 tttagtttct tccctatctg catgtcctct catatagaaa gcccagaatt 5150

 aggggctaga actccaggag agggtctccc cgactcatct cttgctgacg 5200

 gtcaccagga tgcagaaata gggagatggt tagtgggggc caaagatgcc 5250

 ccctcccagg ccttcgtggt tccctcctcc gccccctgca atctttggag 5300

 gagtcagtgc ctcactccag cagtgagtgc ctactgtatg caggtagtca 5350

 gccaggcaaa gagagactaa cggtctcatg ggggaaccct cttgcgggag 5400

 gccgggtagc tggagcgaag cgttccggct gcccttgctg ctgggtggag 5450

 tggagaggga gacttctttt tgttggtttt aatttaaaaa cacaaaggcc 5500

 taaagaaata cgtatcttat aattttttta atttttgaga cgttcattta 5550

 atgaattgtg cacgaatgaa ttctatatat ataaaatata catatatagc 5600

 tctatatttg gggaggggca ctgtctcttt tttctctcat ttttaaaatg 5650

 aagtgttgtt gcctttgtat gtggttcaac catccagctc ccagctggct 5700

 aaactttgcc tccagtggtc aaagatggga aaagagtggg gttggcagga 5750

 gatggaaaac ggaggtgccg ccccagcatg gggggcaggt cccccagtcc 5800

 accctgcccc tccccctgtg gagaagacgc ttagttgggg gtgtgggttt 5850

 gggctccatt ctggattcgg cggttccggg ggaggggtgg gtctgtgccg 5900

 attactctgt cttgtacgtt tgttctgctg ctcttcaata ttgtatcaac 5950

 gccaggaaag gggggtgaaa agcctctttt accccccaaa taaattgtca 6000

 cattccgaag ctga 6014

<210> 4759
<211> 412
<212> PRT
<213> Homo sapien

<400> 4759
 Met Glu Leu Ser Ala Val Gly Glu Arg Val Phe Ala Ala Glu Ser
   1               5                  10                  15

 Ile Ile Lys Arg Arg Ile Arg Lys Gly Arg Ile Glu Tyr Leu Val
                  20                  25                  30

 Lys Trp Lys Gly Trp Ala Ile Lys Tyr Ser Thr Trp Glu Pro Glu
                  35                  40                  45

 Glu Asn Ile Leu Asp Ser Arg Leu Ile Ala Ala Phe Glu Gln Lys
                  50                  55                  60

 Glu Arg Glu Arg Glu Leu Tyr Gly Pro Lys Lys Arg Gly Pro Lys
                  65                  70                  75

 Pro Lys Thr Phe Leu Leu Lys Ala Arg Ala Gln Ala Glu Ala Leu
                  80                  85                  90

 Arg Ile Ser Asp Val His Phe Ser Val Lys Pro Ser Ala Ser Ala
                  95                 100                 105

 Ser Ser Pro Lys Leu His Ser Ser Ala Ala Val His Arg Leu Lys
                 110                 115                 120

 Lys Asp Ile Arg Arg Cys His Arg Met Ser Arg Arg Pro Leu Pro
                 125                 130                 135

 Arg Pro Asp Pro Gln Gly Gly Ser Pro Gly Leu Arg Pro Pro Ile
                 140                 145                 150

 Ser Pro Phe Ser Glu Thr Val Arg Ile Ile Asn Arg Lys Val Lys
                 155                 160                 165

 Pro Arg Glu Pro Lys Arg Asn Arg Ile Ile Leu Asn Leu Lys Val
                 170                 175                 180

 Ile Asp Lys Gly Ala Gly Gly Gly Gly Ala Gly Gln Gly Ala Gly
                 185                 190                 195

 Ala Leu Ala Arg Pro Lys Val Pro Ser Arg Asn Arg Val Ile Gly
                 200                 205                 210

 Lys Ser Lys Lys Phe Ser Glu Ser Val Leu Arg Thr Gln Ile Arg
                 215                 220                 225

 His Met Lys Phe Gly Ala Phe Ala Leu Tyr Lys Pro Pro Pro Ala
                 230                 235                 240

 Pro Leu Val Ala Pro Ser Pro Gly Lys Ala Glu Ala Ser Ala Pro
                 245                 250                 255

 Gly Pro Gly Leu Leu Leu Ala Ala Pro Ala Ala Pro Tyr Asp Ala
                 260                 265                 270

 Arg Ser Ser Gly Ser Ser Gly Cys Pro Ser Pro Thr Pro Gln Ser
                 275                 280                 285

 Ser Asp Pro Asp Asp Thr Pro Pro Lys Leu Leu Pro Glu Thr Val
                 290                 295                 300

 Ser Pro Ser Ala Pro Ser Trp Arg Glu Pro Glu Val Leu Asp Leu
                 305                 310                 315

 Ser Leu Pro Pro Glu Ser Ala Ala Thr Ser Lys Arg Ala Pro Pro
                 320                 325                 330

 Glu Val Thr Ala Ala Ala Gly Pro Ala Pro Pro Thr Ala Pro Glu
                 335                 340                 345

 Pro Ala Gly Ala Ser Ser Glu Pro Glu Ala Gly Asp Trp Arg Pro
                 350                 355                 360

 Glu Met Ser Pro Cys Ser Asn Val Val Val Thr Asp Val Thr Ser
                 365                 370                 375

 Asn Leu Leu Thr Val Thr Ile Lys Glu Phe Cys Asn Pro Glu Asp
                 380                 385                 390

 Phe Glu Lys Val Ala Ala Gly Val Ala Gly Ala Ala Gly Gly Gly
                 395                 400                 405

 Gly Ser Ile Gly Ala Ser Lys
                 410

<210> 4760
<211> 735
<212> DNA
<213> Homo sapien

<400> 4760
 aactggagga agagtatgac aaaaagaatg atatgaaagt gtgaaaagtt 50

 gtttaagtaa tcatgactag tctcctgggt gactggaaaa ttagagacag 100

 tagtggaaga gaggagaaca tgctcatgga cagtgttgaa tggagacaag 150

 gagaaggcct taggatctac tgggggagtc cggaggagca gtctcttctg 200

 tcccgctgga acccatggtc cactgaagtt ccttatgcta ctttcactga 250

 gcatcctatg aaatacacca gtgagaaatt ccttgaaatt tgcaagttgt 300

 ctgggttcat gtctaagctt gttccagcta tccagaatgc ccacaagaat 350

 tcaactggat ctggaagagg aaagaaactg atggtgttaa ctgaacccat 400

 tttgattgag acctacacag ggctgatgtc attcattgga aaccgcaaca 450

 aacttggcta ttcccttgcc cgtgggagta ttggtttttg agagtctttt 500

 tggtaccata agcatatcat ccacagatat gtcactttga aaattccagt 550

 ttgacccacg ctatttttgg actgaaacaa ttaattattt ttaaatgacg 600

 ctttatgatt tagaaattta gtatttccga aaatttaaaa gcttgattgg 650

 actgatagat acacacttta gacctcatac aagaataatc aaattttctt 700

 aaaactagaa aataaatgct gctgagccta tcaaa 735

<210> 4761
<211> 142
<212> PRT
<213> Homo sapien

<400> 4761
 Met Thr Ser Leu Leu Gly Asp Trp Lys Ile Arg Asp Ser Ser Gly
   1               5                  10                  15

 Arg Glu Glu Asn Met Leu Met Asp Ser Val Glu Trp Arg Gln Gly
                  20                  25                  30

 Glu Gly Leu Arg Ile Tyr Trp Gly Ser Pro Glu Glu Gln Ser Leu
                  35                  40                  45

 Leu Ser Arg Trp Asn Pro Trp Ser Thr Glu Val Pro Tyr Ala Thr
                  50                  55                  60

 Phe Thr Glu His Pro Met Lys Tyr Thr Ser Glu Lys Phe Leu Glu
                  65                  70                  75

 Ile Cys Lys Leu Ser Gly Phe Met Ser Lys Leu Val Pro Ala Ile
                  80                  85                  90

 Gln Asn Ala His Lys Asn Ser Thr Gly Ser Gly Arg Gly Lys Lys
                  95                 100                 105

 Leu Met Val Leu Thr Glu Pro Ile Leu Ile Glu Thr Tyr Thr Gly
                 110                 115                 120

 Leu Met Ser Phe Ile Gly Asn Arg Asn Lys Leu Gly Tyr Ser Leu
                 125                 130                 135

 Ala Arg Gly Ser Ile Gly Phe
                 140

<210> 4762
<211> 1015
<212> DNA
<213> Homo sapien

<400> 4762
 aataaataaa tttttaaaaa ccaacctgat gtgaagttga aacacaagac 50

 gcggaaataa aaactcagag tataaatatc tatattgtta ccattatctg 100

 ggataattga tgatttataa gaagctgagg tttcgtcttc ctagaaatgg 150

 acttttatta ggccagcaag aatgaccact tagccattta aatgatttgt 200

 cagcatcttt tgctgctctc ttctaagacc attggttttc actaaaggat 250

 aaatacctgc taagcaaatt ataaaatact ataagacatt taatctcctg 300

 gaagaggact tgctgataat tggatcaaag ttccagcatt attgctcttt 350

 tcgaatcata tggacttagt gttctcatga ccgaggagtc acatttttag 400

 cttgctaaaa tattcactgg agaacatggt gaaatccacg agtggaaacg 450

 ttccatggta ttttcaaacg ccacgtgtca ggaatttggc atgccttcct 500

 ctgggagagg cactggagtg tggccagatg gaacccagca gggtacagag 550

 ggcatttgtg ggagcagtta ggaaaccagg acgtccagct tctgcctgcc 600

 agggagctcg ctcatgttgt ctctgaaatt tgcataagag caattacctc 650

 atattctaat tttaaagata caatttttaa agacatggaa ggctctgagg 700

 cctcctgaag gctattccta tgtgaggtat tgtttacggg tggcctttca 750

 ctatttccaa atcagcgatg aaaagaagac tgagtctaaa ataaatgaag 800

 caacagactt cagcagcctg agagaatttt gttcaattcc agtctcctta 850

 aaaaaaaatc ggtttttgct ttcaatttag gaaaattgtt ttgggttgca 900

 ttgttgaaag taatgatttc tagcagctac ttatgtataa tctcttaacc 950

 aattaaattc tgaatctctt aaatcacttg attattcatg ctggttttag 1000

 ttatccactg ctgta 1015

<210> 4763
<211> 66
<212> PRT
<213> Homo sapien

<400> 4763
 Met Val Lys Ser Thr Ser Gly Asn Val Pro Trp Tyr Phe Gln Thr
   1               5                  10                  15

 Pro Arg Val Arg Asn Leu Ala Cys Leu Pro Leu Gly Glu Ala Leu
                  20                  25                  30

 Glu Cys Gly Gln Met Glu Pro Ser Arg Val Gln Arg Ala Phe Val
                  35                  40                  45

 Gly Ala Val Arg Lys Pro Gly Arg Pro Ala Ser Ala Cys Gln Gly
                  50                  55                  60

 Ala Arg Ser Cys Cys Leu
                  65

<210> 4764
<211> 2400
<212> DNA
<213> Homo sapien

<400> 4764
 tttcatgttt cttttttttt tcccctccag tctgagattt ctgtgtggct 50

 gatggagagt gtgatttggg cgtaggtctt atttgcaaac ctgctcatgt 100

 tctaagcttt cttcaggtag taccacctgt catcgcttct gcatatgatt 150

 taaatggatt tttgttttta taaaagtatc ataaatttag agataaaatg 200

 gaggggaccc agctttcttt acaatgtgga tctacctcag ttaaacagtt 250

 gggtgctatt actaagtctg tcaaattaaa ttggaaaaag taaccaaaca 300

 gtgagataca actccacatg aaacttgaaa ttgtaatttc cgtttattta 350

 atgatatttt tatttatttg tgccttttat gttgaacccc aatgcattga 400

 aaaaattcag tatgaaacag tacatatttt atttatatta caggtgggag 450

 aaaagtccaa ttggtcatgg aatttgatag acttttcccc agccaactgc 500

 tacagtgtat tataatcccg actgcccccc tgtgaaaaga aaaaaaaaaa 550

 tgtccaagag caaatttaac attttacaaa caataaagtc caaactcctc 600

 tatgcacata tttatagctt atcacttcat tttctgtgcc agtgaagggg 650

 tggccagaaa aaaaatccca agtaccctca tcattgcttt tctagccatt 700

 catgccccct cttcctctgg cacattttct aagagtttat ttcataagca 750

 gcaaacggac tgttgtcgat ttcatctctc ctgacctacc tggtggaggt 800

 gctaatggcc atggacagaa aggggcgagc cagagctcgt ggctttgtgg 850

 aggcagaggc ctgcattcag cagcggccct gtgtgcctgt aagttaggaa 900

 ggctttctga caggtaagaa aatgagatag gttgatgact taccatgctt 950

 ttatatttgg cagtttacaa ttctagactt ttcctactat ggcgatcttt 1000

 ttttacttaa ttctttggag gtaacaatat tttggagtct taagaatttg 1050

 attttatacc aataagaaat aaaaattagg gatctttcct gtagtatata 1100

 gttttactat tttaaagaga tctctgaatt ttacaagaga accaacattc 1150

 cttaatggca gaactttgaa agttgatttg ggaggctttt tgctgcagga 1200

 tctcaaaaat agagagagag atgattctac ttaaatgttt ttaattttct 1250

 aacttccatc aggttgatac ttaagctcta ttttgtaaag agtaaatcat 1300

 cctttagtat gctgcataag atgatcagca ttcttgcact ttctcagtaa 1350

 taagacgtgc cgggcaattg gctccccagg acgcattgtg tttttaacct 1400

 aacgagagga ctttggggca ggtgattaaa tttatatagg tacctcaaga 1450

 aaaagaacct gaatatgctg cattttcttt ctttagcttt tacatgtagc 1500

 attttgtttt gcttttgtta tttttgtttt gatatatgct ttttggaccc 1550

 caatagactg ttgaaagaaa tttaaaaatt actcttgtag ggatatagta 1600

 tccttaaaaa ataaaaatta aaaaaaattt aaaaaaattg ctgcaatatc 1650

 tggctcgaag gttgccctat attagaataa tactttagcc aaatacacct 1700

 gaggaggcag acactgtgtt tataagcaga caataatgtt ctgaatcctt 1750

 cctgttcatg ctgctttctt aattcatttc tccatgtcat caagaggttg 1800

 gataacttat ttctaagctc aaggttaaaa atcatgtcac cttttttttt 1850

 tcccccaaca cagacctcag aaaaattgcg attgaggaag tagcatgatc 1900

 ctaaatgtgt tgctgaaatc aggcagcccg agcctctggt ctctccagag 1950

 agcccgtctt cacatttctc tattcctcag cactcacccg aaactgaaca 2000

 gatggggagt ggtcttgatt gtcaagataa aactggtgaa gaaagctaaa 2050

 tgctgagaaa ctgagcatct attgtcgtgt ttaagcttag ctgggtcctt 2100

 tctagtttgt ttttacagct tactaggtga agtagtttgc actatttttg 2150

 caataaattc atggaaaacc taacagttac ttgttttgtt tcttactgtg 2200

 tgtatataaa ctaatactaa aagtttggca tagtgttttt tcacctcctt 2250

 acataacccc taacatgcac agaatgctgt aaatctgata aaatatgatg 2300

 tgaatgatat tttataaagt tattttgtat ggtgtcaatt ttgttttgcc 2350

 tcatagtatg tcagcaaaaa attaaataaa agtcctccta tttacagctg 2400

<210> 4765
<211> 24
<212> PRT
<213> Homo sapien

<400> 4765
 Phe His Val Ser Phe Phe Phe Pro Leu Gln Ser Glu Ile Ser Val
   1               5                  10                  15

 Trp Leu Met Glu Ser Val Ile Trp Ala
                  20

<210> 4766
<211> 2777
<212> DNA
<213> Homo sapien

<400> 4766
 agtgctcttg gccgggagga ggctgtgctg caccagcacc tcttgctcca 50

 catctccaga gagcccaggg ccctgtggcc gagtgtgtcc agcccagtgt 100

 catggggagc ttccatatct catggctcct tgctgggcca agccctccag 150

 aaccccaaac ccccaaagac tgatgaatgc cagagtggcc accttgctta 200

 tctgtggccc cggccctggt gatcaccatg gcagctggga agggagcccc 250

 gttgagccca tcggctgaaa acagatggcg acttagcgaa cctgagctgg 300

 gccggggctg caagccagtg ctgctcgaga agacgaaccg cctgggccct 350

 gaggctgctg tgggcagggc gggccgggat gtgggcagtg cggagctggc 400

 actgttggta gccccaggca agccccgacc tggcaagccg ctgcccccga 450

 agacacgtgg agagcagagg cagagcgcct tcacggagct gccgaggatg 500

 aaggaccggc aggtggatgc tcaggcccag gagagggagc acgatgaccc 550

 cacaggccaa cctggtgccc cacagctgac ccagaacatc cccagaggcc 600

 cagctggcag caaagtcttc tctgtgtggc ccagcggagc acgaagtgag 650

 caaagaagcg cctttagcaa accaaccaag cgaccagcag agaggcctga 700

 gctaacctca gtcttccctg caggggaatc tgcagatgcc ctgggggagc 750

 tgtctggact cctcaacact acagacctcg cttgttgggg tcgactttca 800

 actcccaagc ttttggttgg tgatttgtgg aacttgcaag cattgccaca 850

 gaatgctcca ctctgtagca cttttctggg tgcccctaca ctgtggctgg 900

 agcataccca ggcccaggtg cccccaccct catcatcctc caccacttcg 950

 tgggccctcc tgccacccac cctcacctcc ctgggcttgt ccacccagaa 1000

 ctggtgtgca aagtgcaacc tgtcctttcg cctaacgtcc gacctggtct 1050

 ttcacatgcg atcccaccac aaaaaggagc atgcggggcc tgacccacat 1100

 tctcagaagc ggagagaaga ggcccttgcc tgccctgtgt gccaggagca 1150

 cttccgggag cgccaccacc tctcccggca catgacttct cacagctagc 1200

 aggtgaccgc agaatgacct gctgggtgca gcagccagcc tttggcagag 1250

 gggggctccc tgggcctgcg ttgagggggc tgtcatggtc ctttgcagag 1300

 ctgctgcttt tggcattcat agataaacag ctcaggcata atttgaaaaa 1350

 gccacacctg catgatgtgt tttgaaggaa atgaagtcct gaaataaagt 1400

 gatgggcttt gcaaatccag ggtagaggcc ctaacaggca cagagagcag 1450

 gggcaactcc tggcacacat catgggcttt ggaggcacac aagcctggat 1500

 tcgaatctgg gctctttcac atactagctg tgaccctgga caaagagctt 1550

 taacctgctg agtccccatt ttctcatctg tgaaatggag atgataacac 1600

 tgtgtcttag gttggcattc aggtcacatg aaaggtgtgt ggaaagtggc 1650

 cagcattctg cctgcagacc ctgagcactg agtcaacaag gtttgtgatg 1700

 atgtctgtac tagttagcta ttgttattaa caagatctcc atggcagaca 1750

 agctaaagca tctgcctaag tcgtgagtct gtgggttggc tcaggttaag 1800

 ctgagcaggt ggggatctca gccagcctcc cagactgcac ctcttctatt 1850

 gctctcctct gtccaccgtt ccaggcagca gcactcccac ctggctgctc 1900

 tgatgtcctc gctccctcca ttcctgcctc tcaccatgca cgcatccatt 1950

 gtccacacac acacaaccag ataatcttct gaaagtgtaa ctcagatgat 2000

 gcctccaacc ctgtggctgc ccttcacact tacaggccta accccagcag 2050

 gacctgccag ctgcttcatg aacaagtccc tgcctcatgt taattgcaag 2100

 cactcatttc actctccctg tgtgccaggc aatagcataa gcactggaag 2150

 aatacagatg ttatagtgag tcctacaata gccctggaag gcaagagctg 2200

 tttcctttcc atttctacaa tgagtcaatt gcagatgatg ctataacact 2250

 tccagtgttt ctgacacttc cctgaagcta tacctgctac cttcatgggc 2300

 cgagcttgcc cttatgaggc ccacaggtgg cagtgggcag aggggacccc 2350

 gctataccac ctcgctgctg ttccactgtc tgctcccgtg ttctgaccac 2400

 agctctggtg ccgtttctca agcctgggct tcattcaaca ttttctatct 2450

 agctcttcat ggtgctgctc ctgctatggt tccacagggc ttcttctcgc 2500

 aggtcagctc cttagagagg tctcccagat tccccgtaaa gcagccctgc 2550

 agcctctgcc tctctcagcc gcatcaccct gttgcttcct tcacagcatg 2600

 tctcaccatc tgcaaccatc tttctgtttg tcgtcttgtt gatttgctgc 2650

 ctccacactg tcagctcctt gggaacagag attggtttgt ttactgtgca 2700

 tccctggtgc ccagaacagg gcatggcata ttgttggtgc ataataaata 2750

 ttgtggaaat aaaaaaaaaa aaaaaag 2777

<210> 4767
<211> 340
<212> PRT
<213> Homo sapien

<400> 4767
 Met Pro Glu Trp Pro Pro Cys Leu Ser Val Ala Pro Ala Leu Val
   1               5                  10                  15

 Ile Thr Met Ala Ala Gly Lys Gly Ala Pro Leu Ser Pro Ser Ala
                  20                  25                  30

 Glu Asn Arg Trp Arg Leu Ser Glu Pro Glu Leu Gly Arg Gly Cys
                  35                  40                  45

 Lys Pro Val Leu Leu Glu Lys Thr Asn Arg Leu Gly Pro Glu Ala
                  50                  55                  60

 Ala Val Gly Arg Ala Gly Arg Asp Val Gly Ser Ala Glu Leu Ala
                  65                  70                  75

 Leu Leu Val Ala Pro Gly Lys Pro Arg Pro Gly Lys Pro Leu Pro
                  80                  85                  90

 Pro Lys Thr Arg Gly Glu Gln Arg Gln Ser Ala Phe Thr Glu Leu
                  95                 100                 105

 Pro Arg Met Lys Asp Arg Gln Val Asp Ala Gln Ala Gln Glu Arg
                 110                 115                 120

 Glu His Asp Asp Pro Thr Gly Gln Pro Gly Ala Pro Gln Leu Thr
                 125                 130                 135

 Gln Asn Ile Pro Arg Gly Pro Ala Gly Ser Lys Val Phe Ser Val
                 140                 145                 150

 Trp Pro Ser Gly Ala Arg Ser Glu Gln Arg Ser Ala Phe Ser Lys
                 155                 160                 165

 Pro Thr Lys Arg Pro Ala Glu Arg Pro Glu Leu Thr Ser Val Phe
                 170                 175                 180

 Pro Ala Gly Glu Ser Ala Asp Ala Leu Gly Glu Leu Ser Gly Leu
                 185                 190                 195

 Leu Asn Thr Thr Asp Leu Ala Cys Trp Gly Arg Leu Ser Thr Pro
                 200                 205                 210

 Lys Leu Leu Val Gly Asp Leu Trp Asn Leu Gln Ala Leu Pro Gln
                 215                 220                 225

 Asn Ala Pro Leu Cys Ser Thr Phe Leu Gly Ala Pro Thr Leu Trp
                 230                 235                 240

 Leu Glu His Thr Gln Ala Gln Val Pro Pro Pro Ser Ser Ser Ser
                 245                 250                 255

 Thr Thr Ser Trp Ala Leu Leu Pro Pro Thr Leu Thr Ser Leu Gly
                 260                 265                 270

 Leu Ser Thr Gln Asn Trp Cys Ala Lys Cys Asn Leu Ser Phe Arg
                 275                 280                 285

 Leu Thr Ser Asp Leu Val Phe His Met Arg Ser His His Lys Lys
                 290                 295                 300

 Glu His Ala Gly Pro Asp Pro His Ser Gln Lys Arg Arg Glu Glu
                 305                 310                 315

 Ala Leu Ala Cys Pro Val Cys Gln Glu His Phe Arg Glu Arg His
                 320                 325                 330

 His Leu Ser Arg His Met Thr Ser His Ser
                 335                 340

<210> 4768
<211> 483
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 58-100
<223> Unknown base

<400> 4768
 gtgagccgaa atccacagca ctccagtagc ctaggcgaca gagcaaaact 50

 ccatctcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 100

 gaaattagaa gaataacaag ttattccaaa tgaaggcgta agaaagggaa 150

 taataacaat aataagagga gttgttcatg aggaaaaacc aaagcttgaa 200

 aattcaacaa agccagtgaa gctcattctt gaaaacatga atcacactca 250

 tgaattctaa ctacaatgaa aaagagaaag aaagagcagg catgcatttc 300

 catatgggag tgagccagca gacagcccta cagatcgtac acacgttttc 350

 caaaactaac aatggaacag gcggcaaacc tatgccaata tactagaaat 400

 tgcagattaa atagatgaaa tattctaaac tggagtttac ataatgaaca 450

 taagagtaat cagagaatct gactcatttt aga 483

<210> 4769
<211> 48
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 58-100
<223> Unknown amino acid

<400> 4769
 Met Asn Ser Asn Tyr Asn Glu Lys Glu Lys Glu Arg Ala Gly Met
   1               5                  10                  15

 His Phe His Met Gly Val Ser Gln Gln Thr Ala Leu Gln Ile Val
                  20                  25                  30

 His Thr Phe Ser Lys Thr Asn Asn Gly Thr Gly Gly Lys Pro Met
                  35                  40                  45

 Pro Ile Tyr


<210> 4770
<211> 616
<212> DNA
<213> Homo sapien

<400> 4770
 aaaaaaaaaa aaacctgaga tttttttgga ccttattcaa ggggagagga 50

 gtctggaggg aatgccgctt ggcttcacta ccaaaggttt tatgacttag 100

 cattttaaaa ggttttcctt ttaccaagaa atgcagaaac caagagcaaa 150

 ccccacgtac cagatcactg attcctactg aagcagctag cccgagaaag 200

 gactctctca tactggtctt gggaaatgac ttggcagcct gagccatccc 250

 agcagtggac aaggatggtt aattcttatt ctgtagacgt ccacaggaac 300

 agactaggat ggaaaacaca gttaagcaca gccatgcacc ctgtggctgt 350

 agaaatgccc ctgtgtgaaa gaaaaataaa ttcaagactg gagttttgga 400

 ggaaaaaaaa tacaagtagc atttacaaca gctctttgct ctttaaattt 450

 cttaccattc aataaagtga tccagtcact cacatttgaa ctgagatgcc 500

 ttctccagac tgttctgaca aggtaatgaa aataaaatgc acttggattt 550

 ttccagacat ccacatccac cgtcaagggc tgggaagaaa agcattgttg 600

 cgtggaaacc tgcagc 616

<210> 4771
<211> 79
<212> PRT
<213> Homo sapien

<400> 4771
 Met Thr Trp Gln Pro Glu Pro Ser Gln Gln Trp Thr Arg Met Val
   1               5                  10                  15

 Asn Ser Tyr Ser Val Asp Val His Arg Asn Arg Leu Gly Trp Lys
                  20                  25                  30

 Thr Gln Leu Ser Thr Ala Met His Pro Val Ala Val Glu Met Pro
                  35                  40                  45

 Leu Cys Glu Arg Lys Ile Asn Ser Arg Leu Glu Phe Trp Arg Lys
                  50                  55                  60

 Lys Asn Thr Ser Ser Ile Tyr Asn Ser Ser Leu Leu Phe Lys Phe
                  65                  70                  75

 Leu Thr Ile Gln


<210> 4772
<211> 3848
<212> DNA
<213> Homo sapien

<400> 4772
 ggcagcttct caggtcagcc tcctccgggc ctctccccac tctcctctgc 50

 ccagttctct gtccttatcc acaggcccct cagtgggcac tggccatacc 100

 catgtccagg tgggcacagg cctggtgata tcctggtgag caagctgggg 150

 acccaccctc cttccctttc tggttggcag ctccacatct ggggcaatgt 200

 agagatctgt gcttttggaa ggaggggcaa tttaaattaa gaagtggtta 250

 ggcatgggtc tcgaatctta gcttccccgc gaggtctggg acaagtgaag 300

 agaggtttct tttctggacc tcagtttctc atctgtaaaa tggggtgagt 350

 ctgggaacct gcaccttgga tggctgtcag gggctcagta gaggacctgg 400

 cacacagttt gtgcttggca atctggagca ggtgcagctc ctttcagagt 450

 gacctggatt ggatcctggg gacagcatgt ctcagggccg gagccagttc 500

 ttggaggaga ctctgcgcag ggcatggatc actgtggtgc ccttttcctg 550

 tgcctgtgcc ttctgacttt gcagaatgca acaacagaga catgggaaga 600

 actcctgagc tacatggaga atatgcaggt gtccaggggc cggagctcag 650

 ttttttcctc tcgtcaactc caccagctgg agcagatgct actgaacacc 700

 agcttcccag gctacaacct gaccttgcag acacccacca tccagtctct 750

 ggccttcaag ctgagctgtg acttctctgg cctctcgctg accagtgcca 800

 ctctgaagcg ggtgccccag gcaggaggtc agcatgcccg gggtcagcac 850

 gccatgcagt tccccgccga gctgacccgg gacgcctgca agacccgccc 900

 cagggagctg cggctcatct gtatctactt ctccaacacc cactttttca 950

 aggatgaaaa caactcatct ctgctgaata actacgtcct gggggcccag 1000

 ctgagtcatg ggcacgtgaa caacctcagg gatcctgtga acatcagctt 1050

 ctggcacaac caaagcctgg aaggctacac cctgacctgt gtcttctgga 1100

 aggagggagc caggaaacag ccctgggggg gctggagccc tgagggctgt 1150

 cgtacagagc agccctccca ctctcaggtg ctctgccgct gcaaccacct 1200

 cacctacttt gctgttctca tgcaactctc cccagccctg gtccctgcag 1250

 agttgctggc acctcttacg tacatctccc tcgtgggctg cagcatctcc 1300

 atcgtggcct cgctgatcac agtcctgctg cacttccatt tcaggaagca 1350

 gagtgactcc ttaacacgca tccacatgaa cctgcatgcc tccgtgctgc 1400

 tcctgaacat cgccttcctg ctgagccccg cattcgcaat gtctcctgtg 1450

 cccgggtcag catgcacggc tctggccgct gccctgcact acgcgctgct 1500

 cagctgcctc acctggatgg ccatcgaggg cttcaacctc tacctcctcc 1550

 tcgggcgtgt ctacaacatc tacatccgca gatatgtgtt caagcttggt 1600

 gtgctaggct ggggggcccc agccctcctg gtgctgcttt ccctctctgt 1650

 caagagctcg gtatacggac cctgcacaat ccccgtcttc gacagctggg 1700

 agaatggcac aggcttccag aacatgtcca tatgctgggt gcggagcccc 1750

 gtggtgcaca gtgtcctggt catgggctac ggcggcctca cgtccctctt 1800

 caacctggtg gtgctggcct gggcgctgtg gaccctgcgc aggctgcggg 1850

 agcgggcgga tgcaccaagt gtcagggcct gccatgacac tgtcactgtg 1900

 ctgggcctca ccgtgctgct gggaaccacc tgggccttgg ccttcttttc 1950

 ttttggcgtc ttcctgctgc cccagctgtt cctcttcacc atcttaaact 2000

 cgctctacgg tttcttcctt ttcctgtggt tctgctccca gcggtgccgc 2050

 tcagaagcag aggccaaggc acagatagag gccttcagct cctcccaaac 2100

 aacacagtag tccgggcctc ctggcctgga atcctcagcc tctctggccg 2150

 ccagtagcct gaggctacgg ctcctgctag agagggtggc aggcctgctg 2200

 ctggacccca gaggccactg tgaccgccaa ggggcctttt ccacttccac 2250

 ggcctctcca ggcactgagg ggaaggcatt gctctacctc tccctgacat 2300

 tttgctccgg ggcagatcca accttacctg gggcagcaaa ctttgtcctg 2350

 gtacctgggc ccagctcgcc agggatgtgg gcagagcacc agcctgggca 2400

 tcaggaagcc aagtttcaag gactgtcttt gagtctgtct gtatgacctt 2450

 gggcctgcca cttctcacag accctaggta tccacagctg tgacatgggg 2500

 gcaagcggct ttgtttcagc ctaacccagg agcttagtaa aaattgcata 2550

 agaccagggg gaagagtgtc agcgtggggt gggaattccc gcggcctcca 2600

 cctgcttgct aggggcagga tctcattcag gctgccctgg aagcacctgc 2650

 ttggccctgc caccttcctc caggggaggg ccagatggca tcctggcttg 2700

 gggcgggtgg gacctaccca ggctctgaga ctttactggc ctatgcctga 2750

 ggcctctttt cctttaactc cctaaattat gatgactcca agtccaagcc 2800

 cacccttccc aaagattggg aggttccgcc gttcccagag gctcctcctg 2850

 cggtgctccc aagacttcca tagaccatct ggaccagtag cccatcccgc 2900

 agttttcttg ggggcagagg aaaacgcttc tttctcctcc agctgaatca 2950

 gctggatccc agtgtcctgg ctgtttggtg attgggcaag attgaatttg 3000

 cccaggtagg cgtgagagtg tgggttttaa attcgaagct caggccatag 3050

 tttcagagaa tcacccttac cccagacctt catgagacag tgctcatgaa 3100

 gccagtgcgt ttcccagaac gaacactagg cggcaccgtt ggtccacact 3150

 cagaggccct tggcgccaag actgcatcta gaatcgctca aacacctgtt 3200

 tgcagacccc atgcaccagc tggaggggcc gtaactgcag gactgcgcct 3250

 actgagtgac ccatttcctc caggaggaaa ggcaagacac gcttacacgg 3300

 ccatttgtct cttttcccaa tgcggcggtg cactttcgct cttgggggct 3350

 gcaccccaga catagctggc accagagcag ggtgctcagg tggtgggtgc 3400

 tcagggccct gccccaggcc actgggccgt tttgatgacc tcgaaggtca 3450

 caggcagaaa ataggagcag gatttcccct ggggaaaagt tctcctggga 3500

 catcttctgc tcttctgtac atttctagat gcaaataact ccttcaccag 3550

 gcagtgagtg gcgtaggctc tggagccagg ctgcctgggc tccaatgcca 3600

 gctctgccac ttgctagctg tgagactgtg gacaaaccac tcagcctctg 3650

 tgtgcctcag ttttcctatt tgtaaaatag aggccatagt ggtacctatt 3700

 ttgaagacta agtaaaagaa ttcaaataaa gagacttggc acagagtaag 3750

 tgctcagtaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 3848

<210> 4773
<211> 528
<212> PRT
<213> Homo sapien

<400> 4773
 Met Asp His Cys Gly Ala Leu Phe Leu Cys Leu Cys Leu Leu Thr
   1               5                  10                  15

 Leu Gln Asn Ala Thr Thr Glu Thr Trp Glu Glu Leu Leu Ser Tyr
                  20                  25                  30

 Met Glu Asn Met Gln Val Ser Arg Gly Arg Ser Ser Val Phe Ser
                  35                  40                  45

 Ser Arg Gln Leu His Gln Leu Glu Gln Met Leu Leu Asn Thr Ser
                  50                  55                  60

 Phe Pro Gly Tyr Asn Leu Thr Leu Gln Thr Pro Thr Ile Gln Ser
                  65                  70                  75

 Leu Ala Phe Lys Leu Ser Cys Asp Phe Ser Gly Leu Ser Leu Thr
                  80                  85                  90

 Ser Ala Thr Leu Lys Arg Val Pro Gln Ala Gly Gly Gln His Ala
                  95                 100                 105

 Arg Gly Gln His Ala Met Gln Phe Pro Ala Glu Leu Thr Arg Asp
                 110                 115                 120

 Ala Cys Lys Thr Arg Pro Arg Glu Leu Arg Leu Ile Cys Ile Tyr
                 125                 130                 135

 Phe Ser Asn Thr His Phe Phe Lys Asp Glu Asn Asn Ser Ser Leu
                 140                 145                 150

 Leu Asn Asn Tyr Val Leu Gly Ala Gln Leu Ser His Gly His Val
                 155                 160                 165

 Asn Asn Leu Arg Asp Pro Val Asn Ile Ser Phe Trp His Asn Gln
                 170                 175                 180

 Ser Leu Glu Gly Tyr Thr Leu Thr Cys Val Phe Trp Lys Glu Gly
                 185                 190                 195

 Ala Arg Lys Gln Pro Trp Gly Gly Trp Ser Pro Glu Gly Cys Arg
                 200                 205                 210

 Thr Glu Gln Pro Ser His Ser Gln Val Leu Cys Arg Cys Asn His
                 215                 220                 225

 Leu Thr Tyr Phe Ala Val Leu Met Gln Leu Ser Pro Ala Leu Val
                 230                 235                 240

 Pro Ala Glu Leu Leu Ala Pro Leu Thr Tyr Ile Ser Leu Val Gly
                 245                 250                 255

 Cys Ser Ile Ser Ile Val Ala Ser Leu Ile Thr Val Leu Leu His
                 260                 265                 270

 Phe His Phe Arg Lys Gln Ser Asp Ser Leu Thr Arg Ile His Met
                 275                 280                 285

 Asn Leu His Ala Ser Val Leu Leu Leu Asn Ile Ala Phe Leu Leu
                 290                 295                 300

 Ser Pro Ala Phe Ala Met Ser Pro Val Pro Gly Ser Ala Cys Thr
                 305                 310                 315

 Ala Leu Ala Ala Ala Leu His Tyr Ala Leu Leu Ser Cys Leu Thr
                 320                 325                 330

 Trp Met Ala Ile Glu Gly Phe Asn Leu Tyr Leu Leu Leu Gly Arg
                 335                 340                 345

 Val Tyr Asn Ile Tyr Ile Arg Arg Tyr Val Phe Lys Leu Gly Val
                 350                 355                 360

 Leu Gly Trp Gly Ala Pro Ala Leu Leu Val Leu Leu Ser Leu Ser
                 365                 370                 375

 Val Lys Ser Ser Val Tyr Gly Pro Cys Thr Ile Pro Val Phe Asp
                 380                 385                 390

 Ser Trp Glu Asn Gly Thr Gly Phe Gln Asn Met Ser Ile Cys Trp
                 395                 400                 405

 Val Arg Ser Pro Val Val His Ser Val Leu Val Met Gly Tyr Gly
                 410                 415                 420

 Gly Leu Thr Ser Leu Phe Asn Leu Val Val Leu Ala Trp Ala Leu
                 425                 430                 435

 Trp Thr Leu Arg Arg Leu Arg Glu Arg Ala Asp Ala Pro Ser Val
                 440                 445                 450

 Arg Ala Cys His Asp Thr Val Thr Val Leu Gly Leu Thr Val Leu
                 455                 460                 465

 Leu Gly Thr Thr Trp Ala Leu Ala Phe Phe Ser Phe Gly Val Phe
                 470                 475                 480

 Leu Leu Pro Gln Leu Phe Leu Phe Thr Ile Leu Asn Ser Leu Tyr
                 485                 490                 495

 Gly Phe Phe Leu Phe Leu Trp Phe Cys Ser Gln Arg Cys Arg Ser
                 500                 505                 510

 Glu Ala Glu Ala Lys Ala Gln Ile Glu Ala Phe Ser Ser Ser Gln
                 515                 520                 525

 Thr Thr Gln


<210> 4774
<211> 2154
<212> DNA
<213> Homo sapien

<400> 4774
 tgccatcttg gactcgggct gagtaataaa ttccccccgc accgaaacgc 50

 ggtctttctc tagacgcgtc ttgctgggag agtgtccgtt gcttcccgtc 100

 cgtgtcgcgg ccctgcggtt ggcggcctcc tcgtggagcg gagcaaggcc 150

 aggcggcccc tgctcgagtc ccgcgtcgcc atggccgcgg ttcccgagtt 200

 gctgcagcag caggaggagg accgcagcaa gctgagatct gtatctgtgg 250

 acctgaatgt tgatccctcg cttcagattg acatacctga tgcgctcagt 300

 gagagagaca aagtcaaatt tacagtgcac acaaagacca cactgcccac 350

 gtttcagagc ccagagtttt ctgttacaag gcaacatgaa gactttgtgt 400

 ggctacatga cactcttatt gaaacaacag actatgctgg gcttattatt 450

 ccacctgctc ctacgaagcc cgactttgat ggtcctcgag agaagatgca 500

 gaaactggga gaaggtgaag ggtctatgac caaagaagaa tttgccaaga 550

 tgaaacaaga actggaagct gagtatctcg ctgtgtttaa gaagactgtg 600

 tcctcccatg aagtctttct tcagcggctt tcttctcacc ctgttctcag 650

 taaagatcgc aactttcatg ttttcctgga atatgatcag gatctaagtg 700

 ttaggcggaa aaatactaaa gagatgtttg gtggcttctt caaaagtgtg 750

 gtgaaaagtg ctgatgaagt cctttttact ggagttaagg aggtagatga 800

 cttctttgag caagagaaga acttccttat taactattac aataggatca 850

 aagattcttg tgtgaaagct gacaaaatga ccagatctca taaaaatgtt 900

 gccgatgact atatccacac cgcagcctgc ttacatagcc tggctttaga 950

 agagcccaca gtcatcaaaa agtacctatt gaaggttgct gagctatttg 1000

 aaaaactaag gaaagtagag ggtcgagttt catcagatga agatttgaag 1050

 ctaacagagc tcctccgata ctacatgctc aacattgaag ctgctaagga 1100

 tctcttatac agacgcacca aagccctcat tgactatgag aactcaaaca 1150

 aagctctgga taaggcccgg ttaaagagca aagacgtcaa gttggctgag 1200

 gcacaccagc aggagtgctg ccagaaattt gaacaacttt ccgaatctgc 1250

 aaaagaagaa ctgataaatt tcaaacggaa gagagtggca gcatttagaa 1300

 agaatctaat tgaaatgtct gaactggaaa taaaacatgc caggaacaat 1350

 gtctcccttt tgcagagctg tattgacttg ttcaagaata actgatatgc 1400

 cttcactcag aagaaaagaa atgaatgtga aagaaagcca agcatcactt 1450

 gcacttaaat cattaccacg gaagatatat tagcttcaac tttagtttaa 1500

 aattatgtga ataaatattt tgatttctac aaatcttaac atttaaccat 1550

 gttggtttaa aaatattatt gcttgctact tggacataac taatttttcc 1600

 ttgtgcattt aatacctctg ggcagaatcc aaatactggg ttctcccgta 1650

 gttcgtcttt agttactaag aaagggtgta ggacacatta gccttctgga 1700

 aacaagtaga agccatcacc tggcccatgt ccctacaaac ccatgattgt 1750

 cagggaggtg ccagttacag caggtgattc agctacttga ggtcggtaac 1800

 agaccttcca ttcctcactg aaggtggggt ttgtgttttt gttttgccct 1850

 gttactccac tggtagtcat ctggtgtttg tactataaca acagcaagaa 1900

 aatctcattt atctttatat actctttgca cctccttttt ttagtcgaga 1950

 tataaatatt tgaggggaga gaaatatcta caggtatata tggaaacaaa 2000

 taatgtggtc tgctttataa gatggccaga tctacattag gaaaagtata 2050

 agccccctcc ctaatggccg ctggggggtg agggcggtgt gttgtatgtc 2100

 tttgggtgtt tgttttttta taaagcatat aataaaataa tcgtgctact 2150

 aaaa 2154

<210> 4775
<211> 404
<212> PRT
<213> Homo sapien

<400> 4775
 Met Ala Ala Val Pro Glu Leu Leu Gln Gln Gln Glu Glu Asp Arg
   1               5                  10                  15

 Ser Lys Leu Arg Ser Val Ser Val Asp Leu Asn Val Asp Pro Ser
                  20                  25                  30

 Leu Gln Ile Asp Ile Pro Asp Ala Leu Ser Glu Arg Asp Lys Val
                  35                  40                  45

 Lys Phe Thr Val His Thr Lys Thr Thr Leu Pro Thr Phe Gln Ser
                  50                  55                  60

 Pro Glu Phe Ser Val Thr Arg Gln His Glu Asp Phe Val Trp Leu
                  65                  70                  75

 His Asp Thr Leu Ile Glu Thr Thr Asp Tyr Ala Gly Leu Ile Ile
                  80                  85                  90

 Pro Pro Ala Pro Thr Lys Pro Asp Phe Asp Gly Pro Arg Glu Lys
                  95                 100                 105

 Met Gln Lys Leu Gly Glu Gly Glu Gly Ser Met Thr Lys Glu Glu
                 110                 115                 120

 Phe Ala Lys Met Lys Gln Glu Leu Glu Ala Glu Tyr Leu Ala Val
                 125                 130                 135

 Phe Lys Lys Thr Val Ser Ser His Glu Val Phe Leu Gln Arg Leu
                 140                 145                 150

 Ser Ser His Pro Val Leu Ser Lys Asp Arg Asn Phe His Val Phe
                 155                 160                 165

 Leu Glu Tyr Asp Gln Asp Leu Ser Val Arg Arg Lys Asn Thr Lys
                 170                 175                 180

 Glu Met Phe Gly Gly Phe Phe Lys Ser Val Val Lys Ser Ala Asp
                 185                 190                 195

 Glu Val Leu Phe Thr Gly Val Lys Glu Val Asp Asp Phe Phe Glu
                 200                 205                 210

 Gln Glu Lys Asn Phe Leu Ile Asn Tyr Tyr Asn Arg Ile Lys Asp
                 215                 220                 225

 Ser Cys Val Lys Ala Asp Lys Met Thr Arg Ser His Lys Asn Val
                 230                 235                 240

 Ala Asp Asp Tyr Ile His Thr Ala Ala Cys Leu His Ser Leu Ala
                 245                 250                 255

 Leu Glu Glu Pro Thr Val Ile Lys Lys Tyr Leu Leu Lys Val Ala
                 260                 265                 270

 Glu Leu Phe Glu Lys Leu Arg Lys Val Glu Gly Arg Val Ser Ser
                 275                 280                 285

 Asp Glu Asp Leu Lys Leu Thr Glu Leu Leu Arg Tyr Tyr Met Leu
                 290                 295                 300

 Asn Ile Glu Ala Ala Lys Asp Leu Leu Tyr Arg Arg Thr Lys Ala
                 305                 310                 315

 Leu Ile Asp Tyr Glu Asn Ser Asn Lys Ala Leu Asp Lys Ala Arg
                 320                 325                 330

 Leu Lys Ser Lys Asp Val Lys Leu Ala Glu Ala His Gln Gln Glu
                 335                 340                 345

 Cys Cys Gln Lys Phe Glu Gln Leu Ser Glu Ser Ala Lys Glu Glu
                 350                 355                 360

 Leu Ile Asn Phe Lys Arg Lys Arg Val Ala Ala Phe Arg Lys Asn
                 365                 370                 375

 Leu Ile Glu Met Ser Glu Leu Glu Ile Lys His Ala Arg Asn Asn
                 380                 385                 390

 Val Ser Leu Leu Gln Ser Cys Ile Asp Leu Phe Lys Asn Asn
                 395                 400

<210> 4776
<211> 2561
<212> DNA
<213> Homo sapien

<400> 4776
 tgatatatga aaaagtccaa atgaatataa ggaagtcagt ttggaagctc 50

 ttctagtatt cttggtatta gatcatgaag tgccacaggc tagtgtgata 100

 gatggaggga tggaaaaagt gctgaataca agaaaggaag gttgaatttt 150

 atatatttgt ctataaagtg tcactctggg aataaagctt aaattgtctc 200

 acttatttaa aaaacagttc cagtttgccc acgtgcaaca ttagtgagta 250

 cctaccctgt tcccatgggt tctccaccca cccgaaacaa gcacacactg 300

 ggacaatctg agggtgctca cgtctgccgg tgataaggag gtgttcattt 350

 gcatgatggc atttgtgcat aaaatggtac tgctccagaa gtggttctag 400

 tgaccctgtc ttcaccctag tgtggcaggc cgatggaaca gagcatctgc 450

 attgactgcc atgcgccgat tggaggcatt gaccacaaac ctcgggacgg 500

 ctttcatctg gtcaagtatg tgggtcagga ttctatttcc taagtactca 550

 aactttgggg tgttgggctg tttttattcc agctgataaa gtgatactca 600

 agatagtact aattactcca gtacatgtgg gcctgtgtca tattgaatag 650

 caatgccaaa gtcccagcag tcacacagca gggaggcatc tgatctgttg 700

 ttggatccct gggccctgaa atgcaaagca ggctaccctt taacagctgt 750

 taatatgaat acaggtgtct tccttttggg ccttgggtgc accttctgta 800

 gaaatatgca tgacataaac agatgatcta attcacgagg acatctatgt 850

 ctgcaggacc aaaacctggg catccgtctg tctcagcaga tgccatctca 900

 cttgccagca atcttagctt tctccatttt ttattttttg agaaaaatga 950

 aggagacaga catagtctta tgaaatacca gacttcagaa tccaggtaca 1000

 aatccgatcc cacaatccca tgctgagatg aatgtggttc taaatgctcc 1050

 tttcagagag tgagtgggac ctgcgtgggg gcctcacatt ctgactgttc 1100

 cctgcagtca cagcttaaaa tactttcatg ttatctccag aaactgtcac 1150

 agtgtcctcc atcctctaat agttttgcca ctgagagcat cggccacact 1200

 gcatctcctc tctgccggac tttagatccc ggtttttcct ttggggagat 1250

 gagaacaata tggacaccca tgggatgccg actgtcctcc caaactctag 1300

 ctgttcttag cccaaccgct cctctcctga caaagacttc agtggaaaag 1350

 acgggtccag gcctgcgtct taacaccctg cccggggatc agcatcaata 1400

 ccacacagcg cagccacctg acgctgagaa tgcggtcggg tctggtccac 1450

 cggaaaggcg agtctatcat gagagagact cttaggaaca tggtccaggc 1500

 tttgtggaac agcaagtact cttcacataa ctctcttctc agccgtaagc 1550

 ctcactccaa gtgctgagaa agtgcagcgt gccaaagcgg ccagcctcag 1600

 cctctgtctt gtgttctctc gttctttcca gagacaaggc agacagaacg 1650

 cagaccggcc atgtgctggg caacccgcag cggagagacg tggtgacatg 1700

 tgaccgaggg ctgcccccag tggtcttcct ccttatccgg ctactcactc 1750

 acttggctct gcttctggga gcgtcccaga gttcccaggc tctgataaac 1800

 atcattaagc ctccagtgag ggatccaaaa ggctttctgc agcagcacat 1850

 cctgaaggac ctggagcagt tggccaagat gctgggacac agtgccgacg 1900

 agaccatcgg cgtggtccac ctcgtcctgc gcaggcttct ccaagagcag 1950

 caccagctct ctagcagaag tgaggaaagg ggcaagggct gggcggggat 2000

 cacacagcac aacggcagcg caagcaggct cgctgtcttg tgggccaccc 2050

 cacacacagc cagtctgagc tctgtctgtg ctgttgctgg aaagaatgag 2100

 agaacacaca gagagaaaac cgtgtctagg gaaggcgatg cctggggctg 2150

 gaaaaaggaa gcactctgct tgcccagagg ctggaaggag ctgctctgtt 2200

 ccctccattc acccctgcct ggctaagacc tgcggtattc gggagcgtct 2250

 gcacgcaagt gttcagtgtg catatatggg gagtcttcag ttccgaagtc 2300

 agccccgtag gtcattcccc taccatgctg ggagcacgtg tcgtccacac 2350

 agagcgtgcg tgtcaaagga tcaatcacca tcacagttgt gtgctgattt 2400

 attaaatgtt tatatgtcca cagttatgtt aaaaaaaaaa agctataaaa 2450

 tattgtattc actgagctaa ctttctattt taaaaattta aatccataca 2500

 gaaagaaaag gtctgtaaga caacttagta aaatggttat atggttatct 2550

 gtgaaaaaaa t 2561

<210> 4777
<211> 124
<212> PRT
<213> Homo sapien

<400> 4777
 Met Arg Glu His Thr Glu Arg Lys Pro Cys Leu Gly Lys Ala Met
   1               5                  10                  15

 Pro Gly Ala Gly Lys Arg Lys His Ser Ala Cys Pro Glu Ala Gly
                  20                  25                  30

 Arg Ser Cys Ser Val Pro Ser Ile His Pro Cys Leu Ala Lys Thr
                  35                  40                  45

 Cys Gly Ile Arg Glu Arg Leu His Ala Ser Val Gln Cys Ala Tyr
                  50                  55                  60

 Met Gly Ser Leu Gln Phe Arg Ser Gln Pro Arg Arg Ser Phe Pro
                  65                  70                  75

 Tyr His Ala Gly Ser Thr Cys Arg Pro His Arg Ala Cys Val Ser
                  80                  85                  90

 Lys Asp Gln Ser Pro Ser Gln Leu Cys Ala Asp Leu Leu Asn Val
                  95                 100                 105

 Tyr Met Ser Thr Val Met Leu Lys Lys Lys Ser Tyr Lys Ile Leu
                 110                 115                 120

 Tyr Ser Leu Ser


<210> 4778
<211> 2078
<212> DNA
<213> Homo sapien

<400> 4778
 atgggttggg cattaggaac ggcctggccc cacaaatcac acaactgggg 50

 tgtagaacaa aatggttcca cagatgacac caggctggtc cagggccgat 100

 gcaggccaga accccgctgg gaggactccc cagaacaggc actgagctga 150

 ggaaaggcag gacacgtggt ctgctaccga ccccaccaga tcttgctggg 200

 actctgggca gctccggagt aagagcagca tgctctgcaa cgaagagcta 250

 ggtccaagga ccgcaggcgg aggcaggaag tgtcaagatc ccaggttacg 300

 gaatggcacc aagtcggtaa ccaaaggaag caacaacccg ggttttcaag 350

 gcagtcgtgc aaggcggcgc gggggcgagg ccgaggccac tccctcccac 400

 ttccttgacg ctatttcctg ggaggagccg gagctcgcgg cccggagcca 450

 agagattccc agcccagtgc tccaaaatac tcggcctggg ggaggctggt 500

 ccgtgagcgt gcgcccggac cgttccgcca tgcatagtgg acccagcact 550

 acagcaagcc tggcacgacc tctaaggcgg ttcgcggcaa cgtccgcacg 600

 tcggctcgtt ggtctagggg tatgattctc gcttcgggtg cgagaggtcc 650

 cgggttcaaa tcccggacga gccctccttt accttttact gagacaagag 700

 tgtcttcaag gaatatgtta cctgaccagc gctgcaggag gcttgactgt 750

 aagtcatcaa tgtacagtaa gctcttttgt ggcaccgcgg tagcagaaag 800

 catctcaatc cccagacccg cctggcatgt caggaagaga cgaggcacgc 850

 ccagacttgg gcaggtccct ccctttctgc ttcctgactt ccttcctggt 900

 gtctcaactc ggccaccaca gcctggtttc gctttgattg acacgcgtca 950

 atctatagtt gtggatgaca gtgttcggga gagcccagga actgtcaaaa 1000

 cttggttctc tgcagtcctg aaggcactct gtctctttcg gtcactccat 1050

 ctgacgattg gtgcctgaaa tacacctacg gtttctggtc agcgtttatc 1100

 agtggttgga agaacagaac ccctaggaac cctgctgtca gcacgcagag 1150

 tgtaaagtct cagatcaagg attcggagaa aggtctctac aggtccctcc 1200

 tcgttagtat agtggttggt tgggatgagt cgggttggac ccgtgcggat 1250

 ccaggaaaac agcgatcgag gtaaaagtaa tggctgccgt cgtctgccca 1300

 gcgcgcaatt gtgagtgacc ttcaccgcta gcgcgcgcca cccaccccac 1350

 atgaacctgt agggttatgc ccagtctaca gacgaggaaa ccaagatcca 1400

 gggaagctga gtcaccggca gagctgggat tacgtctaag atttgtccag 1450

 ggggcgagaa ctgcagcgac accatgatga tttatcatct ccagaaaaca 1500

 aaaaaaaagg cctagacaca taaaaatggc ttctctgtag agtgagctca 1550

 acgagctcaa tgtgattcca gttaaggaat tgggccttaa gccaaatgcg 1600

 cctaaacgca acttgcctct ctattattta tccagaggat gaatttaatt 1650

 cctacgtaca tgcgcccaca tctcgtcagc tggtgcctca gagaaatgcg 1700

 ctgacaaatc ttaaaggtgg ggcttcatga caaaagtccg cccgttattg 1750

 ctgctcaaca gacccatcaa gtcacgctgt tggacaggcc tcgtggcgca 1800

 acggtagcgc gtctgactcc agatcagaag gttgcgtgtt caaatcacgt 1850

 cggggtcaaa caaaacattg ttttccctaa tcaaatagac ctacggtgac 1900

 atttttcagg ataggaaaaa aaaaaagcct cctcagtaga aggataggag 1950

 gggaatgaga caaatatgaa cgttattcag aagttgggtg cagactttca 2000

 acattatgtg atatatccct gtggcaaaac tgcgcatgta tccctaaggt 2050

 ctataaaagt aaaaataaat ttaaaaat 2078

<210> 4779
<211> 148
<212> PRT
<213> Homo sapien

<400> 4779
 Met Ile Leu Ala Ser Gly Ala Arg Gly Pro Gly Phe Lys Ser Arg
   1               5                  10                  15

 Thr Ser Pro Pro Leu Pro Phe Thr Glu Thr Arg Val Ser Ser Arg
                  20                  25                  30

 Asn Met Leu Pro Asp Gln Arg Cys Arg Arg Leu Asp Cys Lys Ser
                  35                  40                  45

 Ser Met Tyr Ser Lys Leu Phe Cys Gly Thr Ala Val Ala Glu Ser
                  50                  55                  60

 Ile Ser Ile Pro Arg Pro Ala Trp His Val Arg Lys Arg Arg Gly
                  65                  70                  75

 Thr Pro Arg Leu Gly Gln Val Pro Pro Phe Leu Leu Pro Asp Phe
                  80                  85                  90

 Leu Pro Gly Val Ser Thr Arg Pro Pro Gln Pro Gly Phe Ala Leu
                  95                 100                 105

 Ile Asp Thr Arg Gln Ser Ile Val Val Asp Asp Ser Val Arg Glu
                 110                 115                 120

 Ser Pro Gly Thr Val Lys Thr Trp Phe Ser Ala Val Leu Lys Ala
                 125                 130                 135

 Leu Cys Leu Phe Arg Ser Leu His Leu Thr Ile Gly Ala
                 140                 145

<210> 4780
<211> 3193
<212> DNA
<213> Homo sapien

<400> 4780
 gtgggaccgc tgaccgcgcg gctgctccgc tctccccgct ccaagcgccg 50

 atctgggcac ccgccaccag catggacgct cgccgcgtgc cgcagaaaga 100

 tctcagagta aagaagaact taaagaaatt cagatatgtg aagttgattt 150

 ccatggaaac ctcgtcatcc tctgatgaca gttgtgacag ctttgcttct 200

 gataattttg caaacacgag gctgcagtca gttcgggaag gctgtaggac 250

 ccgcagccag tgcaggcact ctggacctct cagggtggcg atgaagtttc 300

 cagcgcggag taccagggga gcaaccaaca aaaaagcaga gtcccgccag 350

 ccctcagaga attctgtgac tgattccaac tccgattcag aagatgaaag 400

 tggaatgaat tttttggaga aaagggcttt aaatataaag caaaacaaag 450

 caatgcttgc aaaactcatg tctgaattag aaagcttccc tggctcgttc 500

 cgtggaagac atcccctccc aggctccgac tcagtaagta ccagttcttg 550

 tttatataca gtagtgtttt gggcacacct aaggtcgatc tgtgttgtat 600

 ttaaaaatct aatttcttta tttgtgtggc cttctagaca aacgaagggg 650

 acctagagga aaccccctga cagatctctg gatgatcctc cttgaatcct 700

 gggcagtttg gtctctcctt gctgtgctcc tgtggcacta aactcctttt 750

 gattggttct ttctttcctt cccagctaga ctaagcccct catgggcagg 800

 taatgaagat tgaaaacttt tttctgttct ccagtgtgag cacattcctc 850

 ctacatggta gatgtgcaat agatgttttt aaaattggag aatgaaaata 900

 aaagaagaaa atcacaattt cttatcaagt tgtagcttgg tatcatacac 950

 aattgcattc tgaggaatta aggtggtaca acttagggag atttggtgtg 1000

 tctgctgtga tagaaaagat ttctttttcc tggctttccc tgaggaaagg 1050

 aaagatggaa agagggaagc catacagata tccctctgtt ttgcagtgta 1100

 gaaactgaat gtgtttctac agggtcaaga gacattagag aaattttttt 1150

 tttttagaac agaagatcat ttcttacatc ttcattaagt aaaagaataa 1200

 atagctcatc tctcaagttg aaagaaactg ggcttggtat tattacaaaa 1250

 gcaaaattaa aatggccata taggttttag gctcattttg ccatgcatta 1300

 tgcaaaggac aaagaaaaag aaaaaataga gctctcttta cttaaaacat 1350

 ccttaaggag aagctatgaa ttccccaaag tactacttct ctttattatg 1400

 gaataaatgg attcccttat acgtgctttg tttagcaatc aaggagaccg 1450

 cgaaggcgta cattcccggg tgttgcttcc aggagaaacc ctgaacggag 1500

 agctcgtcct cttaccaggt caaggtcccg gatcctcggg tcccttgacg 1550

 ctctacccat ggaggaggag gaggaagagg ataagtacat gttggtgaga 1600

 aagaggaaga ccgtggatgg ctacatgaat gaagatgacc tgcccagaag 1650

 ccgtcgctcc agatcatccg tgacccttcc gcatataatt cgcccagtgg 1700

 aagaaattac agaggaggag ttggagaacg tctgcagcaa ttctcgagag 1750

 agatatataa ccgttcactg aactggcatt gcccgccttg tcgaggaatc 1800

 tgcaactgca gtttctgccg gcagcgagat ggacggtgtg cgactggggt 1850

 ccttgtgtat ttagccaaat atcatggctt tgggaatgtg catgcctact 1900

 tgaaaagcct gaaacaggaa tttgaaatgc aagcataata tctggaaaat 1950

 ttgctgcctg ccttctactt ctcaaatctt tcttgtaaaa gtttccaatt 2000

 ttttcactga aacctgagtt aaaaatcttg atgatcagcc tgtttcataa 2050

 gaaactccaa tcaagttaat cttagcagac atgtgtttct ggagcatcac 2100

 agaaggtata ttgctagtta cactttgccc tcctgcagtt tcttctctgc 2150

 tcccaacccc catctcatag catccccctc tatttccaat gctcctctcc 2200

 aaccgcttag tttctgaatt tcttttaaat tacagtttta tgaaagcata 2250

 ttttatttac ttggtgttga aatagccctc ataaaaccta agcacttgga 2300

 aacacaataa tagtattaac taactagatc tattgaattt cagagaagag 2350

 ccttctaact tgtttacaca aaaacgagta tgatttagca ctcatactag 2400

 ttgaaatttt taatagaatc aaggcacaaa agtcttaaaa ccatgtggaa 2450

 aaattaggta attattgcag attgatgtct ctcaatccca tgtattgcgc 2500

 ttatgttaca agttgttgtc acagttgaga cttaatttct cctaatttct 2550

 tctgcccgaa gggtaagtgg tgcgtccagc ttacacgatc ataattcaaa 2600

 ggttggtggg caatgtaata cttaattaaa ataatgatgg aagagctatc 2650

 tggagattat gagtaagctg atttgaattt tcagtataaa actttagtat 2700

 aattgtagtt tgcaaagttt atttcagttc acatgtaagg tattgcaaat 2750

 aaattcttgg acaattttgt atggaaactt gatattaaaa actagtctgt 2800

 ggttctttgc agtttcttgt aaatttataa accaggcaca aggttcaagt 2850

 ttagatttta agcactttta taacaatgat aagtgccttt ttggagatgt 2900

 aacttttagc agtttgttaa cctgacatct ctgccagtct agtttctggg 2950

 caggtttcct gtgtcagtat tccccctcct ctttgcatta atcaaggtat 3000

 ttggtagagg tggaatctaa gtgtttgtat gtccaattta cttgcatatg 3050

 taaaccattg ctgtgccatt caatgtttga tgcataattg gaccttgaat 3100

 cgataagtgt aaatacagct tttgatctgt aatgctttta tacaaaagtt 3150

 tattttaata ataaaatgtt tgttccaaaa aaaaaaaaaa aaa 3193

<210> 4781
<211> 217
<212> PRT
<213> Homo sapien

<400> 4781
 Gly Thr Ala Asp Arg Ala Ala Ala Pro Leu Ser Pro Leu Gln Ala
   1               5                  10                  15

 Pro Ile Trp Ala Pro Ala Thr Ser Met Asp Ala Arg Arg Val Pro
                  20                  25                  30

 Gln Lys Asp Leu Arg Val Lys Lys Asn Leu Lys Lys Phe Arg Tyr
                  35                  40                  45

 Val Lys Leu Ile Ser Met Glu Thr Ser Ser Ser Ser Asp Asp Ser
                  50                  55                  60

 Cys Asp Ser Phe Ala Ser Asp Asn Phe Ala Asn Thr Arg Leu Gln
                  65                  70                  75

 Ser Val Arg Glu Gly Cys Arg Thr Arg Ser Gln Cys Arg His Ser
                  80                  85                  90

 Gly Pro Leu Arg Val Ala Met Lys Phe Pro Ala Arg Ser Thr Arg
                  95                 100                 105

 Gly Ala Thr Asn Lys Lys Ala Glu Ser Arg Gln Pro Ser Glu Asn
                 110                 115                 120

 Ser Val Thr Asp Ser Asn Ser Asp Ser Glu Asp Glu Ser Gly Met
                 125                 130                 135

 Asn Phe Leu Glu Lys Arg Ala Leu Asn Ile Lys Gln Asn Lys Ala
                 140                 145                 150

 Met Leu Ala Lys Leu Met Ser Glu Leu Glu Ser Phe Pro Gly Ser
                 155                 160                 165

 Phe Arg Gly Arg His Pro Leu Pro Gly Ser Asp Ser Val Ser Thr
                 170                 175                 180

 Ser Ser Cys Leu Tyr Thr Val Val Phe Trp Ala His Leu Arg Ser
                 185                 190                 195

 Ile Cys Val Val Phe Lys Asn Leu Ile Ser Leu Phe Val Trp Pro
                 200                 205                 210

 Ser Arg Gln Thr Lys Gly Thr
                 215

<210> 4782
<211> 3076
<212> DNA
<213> Homo sapien

<400> 4782
 acacagagcc gcctttcagc cgcccgagaa ctgcccgccg cactccgcga 50

 ctgcggcgcc tgctctcggg ccggggtctg cgcgcaccac gcggccggca 100

 gaaagggtaa gagaagggaa ccccgctttg cagggctcca acttcggcgg 150

 acgcgttacg gcgagggcga aatgagtcgg ccgtgaacgg tgtttcctgt 200

 tccgaatccc gagagccctg gaaagttttg aaggaggagg catggcccgg 250

 cagccttatc gttttcccca ggcaaggatt ccggagagag gatcaggtgt 300

 tttcaggtta accgtcagaa acgcaatggc acatcgtgat tctgagatga 350

 aaggagaatg tctaagggaa gacctgaagt tttacttcat gagcccttgt 400

 gaaaaatacc gagccagacg ccagattccg tgaaaactgg gtttgcagat 450

 tttgaagata gtcatggtca ccacacagct tgttcgtttt ggtttaagta 500

 accagctggt ggttgctttc aaagaagata acactgttgc ttttaagcac 550

 ttgtttttga aaggatattc tggtacagat gaagatgact acagctgcag 600

 tgtatatact caagaggatg cctatgagag catctttttt gctattaatc 650

 agtatcatca gctaaaggac attaccctgg ggacccttgg ttatggagaa 700

 aatgaagaca atagaattgg cttaaaagtc tgtaagcagc attacaagaa 750

 agggaccatg tttccttcta atgagacact gaatattgac aacgacgttg 800

 agctcatttc ttgttctttc attgccctag attgtgttca attagacctt 850

 caggacctct ccaagaagcc tccggactgg aagaactcat cattcttcag 900

 actggaattt tatcggctct tacaggttga aatctccttt catcttaaag 950

 gcattgacct acagacaatt cattcccgtg agttaccaga ctgttatgtc 1000

 tttcagaata cgattatctt tgacaataaa gctcacagtg gcaaaatcaa 1050

 aatctatttt gacagtgatg ccaaaattga agaatgtaaa gacttgaaca 1100

 tatttggatc tactcagaaa aatgctcagt atgtcctggt gtttgatgca 1150

 tttgtcattg tgatttgctt ggcatctctt attctgtgta caagatccat 1200

 tgttcttgct ctaaggttac ggaagagatt tctaaatttc ttcctggaga 1250

 agtacaagcg gcctgtgtgt gacaccgacc agtgggagtt catcaacggc 1300

 tggtatgtcc tggtgattat cagcgaccta atgacaatca ttggctccat 1350

 attaaaaatg gaaatcaaag caaagaatct cacaaactat gatctctgca 1400

 gcatttttct tggaacctct acgctcttgg tttgggttgg agtcatcaga 1450

 tacctgggtt atttccaggc atataatgtg ctgattttaa caatgcaggc 1500

 ctcactgcca aaagttcttc ggttttgtgc ttgtgctggt atgatttatc 1550

 tgggttacac attctgtggc tggattgtct taggaccata ccatgacaag 1600

 tttgaaaatc tgaacacagt tgctgagtgt ctgttttctc tggtcaacgg 1650

 tgatgacatg tttgcaacct ttgcccaaat ccagcagaag agcatcttgg 1700

 tgtggctgtt cagtcgtctg tatttatatt ccttcatcag cctttttata 1750

 tatatgattc tcagtctttt tattgcactt attacagatt cttatgacac 1800

 cattaagaaa ttccaacaga atgggtttcc tgaaacggat ttgcaggaat 1850

 tcctgaagga atgcagtagc aaagaagagt atcagaaaga gtcctcagcc 1900

 ttcctgtcct gcatctgctg tcggaggagg aaaagaagtg atgatcactt 1950

 gatacctatt agctaaagtt ctgctaaaga tgattaaagt tcaggcatcc 2000

 ttatccagcg gctgagcaga ggaaccccaa atgacttgga caagcagttc 2050

 caaaatgact ctcttattta attgtggagt gggaaagagg actcacagtt 2100

 agccagctga ccatgactga agttccagct ttacttttta taaacttgaa 2150

 tgataaagaa tagaccatgg gctactactg ggcattagtg caatataaca 2200

 gcgataataa aattctctat tagtctgtta atttatgaca tgatctcgga 2250

 atggaaaaag atcatttcag agtgtgcgaa ataatagtct ttaaccatgt 2300

 aattaaatat gtgtgtttat tgtcaaataa ggatttgttt taaaggtgat 2350

 tcttgggttt gaagacattt gttaattcat ggtctgtaca gaaatgaagc 2400

 tggttgcaat accaatctag agagtccaag ctggcgaact attaagctgt 2450

 ttaaagatca cccttggcct ggcacagtgg ttcacacctg taatcccagc 2500

 actttgggag gcctaggcag gcagactgag ctcaggagct tgagaccagc 2550

 ctgggcaaca tggcaaaaac ccacctctac aaaaagtaca aaaattagtc 2600

 gggcgtgatg gcaggcatct gtagtcccag ctacttggga agctgaagtg 2650

 ggaggatcac ctgagctctg gaggtggagg ctgccatgag ccatgatcgt 2700

 gccactacac tccagcctgg gtgacagagt gagatcctgt ctcaaaaaaa 2750

 aaaaaaaatc acccttaaat caacaaaaag acctcatgct catgcagtgg 2800

 acatttcttg gcctgttttc ctgtgggttt tcttcagcat gatatgaagc 2850

 aactgttggc atagccagtg ggataaataa gaaatggaat catttggctg 2900

 cctcgtcact tgtgctaatg gtcagttgta cacacatgac atgtggaagt 2950

 gacctgtagc agcggtcact cattttaaca attgaactct gctgggttgg 3000

 gtatttacct ttgtctagaa aagaaatatg atatattttc tctaaataaa 3050

 tttattttct aagttaaaaa gaaaaa 3076

<210> 4783
<211> 500
<212> PRT
<213> Homo sapien

<400> 4783
 Met Val Thr Thr Gln Leu Val Arg Phe Gly Leu Ser Asn Gln Leu
   1               5                  10                  15

 Val Val Ala Phe Lys Glu Asp Asn Thr Val Ala Phe Lys His Leu
                  20                  25                  30

 Phe Leu Lys Gly Tyr Ser Gly Thr Asp Glu Asp Asp Tyr Ser Cys
                  35                  40                  45

 Ser Val Tyr Thr Gln Glu Asp Ala Tyr Glu Ser Ile Phe Phe Ala
                  50                  55                  60

 Ile Asn Gln Tyr His Gln Leu Lys Asp Ile Thr Leu Gly Thr Leu
                  65                  70                  75

 Gly Tyr Gly Glu Asn Glu Asp Asn Arg Ile Gly Leu Lys Val Cys
                  80                  85                  90

 Lys Gln His Tyr Lys Lys Gly Thr Met Phe Pro Ser Asn Glu Thr
                  95                 100                 105

 Leu Asn Ile Asp Asn Asp Val Glu Leu Ile Ser Cys Ser Phe Ile
                 110                 115                 120

 Ala Leu Asp Cys Val Gln Leu Asp Leu Gln Asp Leu Ser Lys Lys
                 125                 130                 135

 Pro Pro Asp Trp Lys Asn Ser Ser Phe Phe Arg Leu Glu Phe Tyr
                 140                 145                 150

 Arg Leu Leu Gln Val Glu Ile Ser Phe His Leu Lys Gly Ile Asp
                 155                 160                 165

 Leu Gln Thr Ile His Ser Arg Glu Leu Pro Asp Cys Tyr Val Phe
                 170                 175                 180

 Gln Asn Thr Ile Ile Phe Asp Asn Lys Ala His Ser Gly Lys Ile
                 185                 190                 195

 Lys Ile Tyr Phe Asp Ser Asp Ala Lys Ile Glu Glu Cys Lys Asp
                 200                 205                 210

 Leu Asn Ile Phe Gly Ser Thr Gln Lys Asn Ala Gln Tyr Val Leu
                 215                 220                 225

 Val Phe Asp Ala Phe Val Ile Val Ile Cys Leu Ala Ser Leu Ile
                 230                 235                 240

 Leu Cys Thr Arg Ser Ile Val Leu Ala Leu Arg Leu Arg Lys Arg
                 245                 250                 255

 Phe Leu Asn Phe Phe Leu Glu Lys Tyr Lys Arg Pro Val Cys Asp
                 260                 265                 270

 Thr Asp Gln Trp Glu Phe Ile Asn Gly Trp Tyr Val Leu Val Ile
                 275                 280                 285

 Ile Ser Asp Leu Met Thr Ile Ile Gly Ser Ile Leu Lys Met Glu
                 290                 295                 300

 Ile Lys Ala Lys Asn Leu Thr Asn Tyr Asp Leu Cys Ser Ile Phe
                 305                 310                 315

 Leu Gly Thr Ser Thr Leu Leu Val Trp Val Gly Val Ile Arg Tyr
                 320                 325                 330

 Leu Gly Tyr Phe Gln Ala Tyr Asn Val Leu Ile Leu Thr Met Gln
                 335                 340                 345

 Ala Ser Leu Pro Lys Val Leu Arg Phe Cys Ala Cys Ala Gly Met
                 350                 355                 360

 Ile Tyr Leu Gly Tyr Thr Phe Cys Gly Trp Ile Val Leu Gly Pro
                 365                 370                 375

 Tyr His Asp Lys Phe Glu Asn Leu Asn Thr Val Ala Glu Cys Leu
                 380                 385                 390

 Phe Ser Leu Val Asn Gly Asp Asp Met Phe Ala Thr Phe Ala Gln
                 395                 400                 405

 Ile Gln Gln Lys Ser Ile Leu Val Trp Leu Phe Ser Arg Leu Tyr
                 410                 415                 420

 Leu Tyr Ser Phe Ile Ser Leu Phe Ile Tyr Met Ile Leu Ser Leu
                 425                 430                 435

 Phe Ile Ala Leu Ile Thr Asp Ser Tyr Asp Thr Ile Lys Lys Phe
                 440                 445                 450

 Gln Gln Asn Gly Phe Pro Glu Thr Asp Leu Gln Glu Phe Leu Lys
                 455                 460                 465

 Glu Cys Ser Ser Lys Glu Glu Tyr Gln Lys Glu Ser Ser Ala Phe
                 470                 475                 480

 Leu Ser Cys Ile Cys Cys Arg Arg Arg Lys Arg Ser Asp Asp His
                 485                 490                 495

 Leu Ile Pro Ile Ser
                 500

<210> 4784
<211> 2367
<212> DNA
<213> Homo sapien

<400> 4784
 gatattcttg caggagatcg tgcaagaata tccccgcaca tcaaagatgg 50

 agagaaagat aaacacagag aaaaacatcc gaattcatcc cctaggacat 100

 ataaatggag ctttcagctc aatgaattag ataatatgaa cagtacagag 150

 agaatctcat ttctccaaga aaaactacag gaaatcagaa aatattatat 200

 gtctttgaag tctgaagttg caacgcatag acaggaggag aaaaagatta 250

 aaaaagaaag acagggaagt gtctcatgcg ggagcctcca tgtcatctgc 300

 ttcatcagac actggaatga gtccctcatc atcatctccc ccacaaaatg 350

 tacttgctgt agaatgcagg tgataaacat tttctctacc ttcccagcag 400

 tttgctgcca tggacataaa tccccaaacc ctgaattaca accacagaaa 450

 gcactcaact ggtttgacat tgctaagtat atcctgtata cttttccagg 500

 ctggattgta tctattcccc tctctcttct ttttttcttg ttgcaaaaaa 550

 taagctgatt aataagtgaa ggttaagcag cctgccatat ttgtcataat 600

 ttttcctctt tacttttgtt tttcgtttgt tgtgatatag aacaaagggc 650

 acttagcaaa tttgaatttg tataataaag ctttcaggtg ttacagaaat 700

 cgtagacaag caagtgcaca tgataaacat caaaatatta cccagctgaa 750

 tagttactgc tgcactttca ctaagatgta tttgaacact tggtgagtag 800

 ggggtttatg ttgtgttttt tttcattatc gtttttttta tttttgtgga 850

 agcacttgct atttagaact gccaaagtat atgttcagca gtgtgcccag 900

 gattgaaggt gtaaatggga caaaataaat tgtgaaagga agtgtagttg 950

 actgaaaact acagttgtaa taagtcttcc actttttata ggatttttga 1000

 gcacacaatt atgcaaatat tttaatgttt attaatgttt acagtggaat 1050

 tgtgaataag ttttcagtgg actatcttat cccttgacaa aaatattttg 1100

 tcttttttct atgtaatttc agagttttta ttttgttaca aaaagacaaa 1150

 aatgaaatat ataacaacaa tgaagttatt taacaagatt tctaaagctg 1200

 aaatttttgt gtaaaataag gtattatctt gcaacttgtt aaatatattt 1250

 attcagacat tggatgttgt atttttatgt attttttaaa atattaataa 1300

 aatttaaaaa aagaaaattc taggttaatt cactctttgg atgacaatag 1350

 ctctcagctg tcctttttac aggaggttgc atcctgcagc cttgcctgtg 1400

 ttaaagggag tctgtctcag tccatcaaac agtatagaac tataaatggg 1450

 catctggatc attaaagtat gtccttgttt agaaactttg gcagtcctag 1500

 tatttaaact gttttgagga tcaaattttt ggttgccctt aagatacttt 1550

 gtcacagttt ttatgtttgc tatactgccg aatgaattta tatctcccaa 1600

 agttgagatg caacaactaa gtaaagcaac tatgtatgct ttgtctgtga 1650

 attgttccac agactgatag attttgtaaa taattcttcc aaaatcatgt 1700

 atttaaagca gttttgcata tacattatgt aaaaaggtga ttttataaaa 1750

 gcagttttta aattcatgtt tgtacattga aaggggtttt ttttttaaac 1800

 ctccttttct gtgtttaata tgctgtagaa taataaccta gatgctctag 1850

 actgtatatc aggatctgat ttacaagaaa aagtcagagc taaacactag 1900

 tgatggcata gcattactga aatcattgtt tcttaatttc attttactac 1950

 attgtgaact tgtgattcag attccatttt ctcagagaat taaaaacaaa 2000

 aaaagtactc ttgtaaaatg cacttttctg tcttttcttt gcaaagcaga 2050

 agtatctcaa tgtaaaataa aaatggagct cagtgggcag tattaataaa 2100

 ggccatgttt taaacatagg ctttatactt ttagttttca tttaagtgat 2150

 tgcttttttc ctaagtgctt gtaacttaca gttggaaaat cagatttcac 2200

 aaaaccaagc attttagtat attcagcctt tacaataaaa tatttctact 2250

 aattataaaa atgaaaaaaa aagtgtcatt taaatccatt tggacctagg 2300

 aggcaacctt agatttatac attaaatatt ttaatgattt ccttctgtag 2350

 caattcaata aatgtga 2367

<210> 4785
<211> 185
<212> PRT
<213> Homo sapien

<400> 4785
 Asp Ile Leu Ala Gly Asp Arg Ala Arg Ile Ser Pro His Ile Lys
   1               5                  10                  15

 Asp Gly Glu Lys Asp Lys His Arg Glu Lys His Pro Asn Ser Ser
                  20                  25                  30

 Pro Arg Thr Tyr Lys Trp Ser Phe Gln Leu Asn Glu Leu Asp Asn
                  35                  40                  45

 Met Asn Ser Thr Glu Arg Ile Ser Phe Leu Gln Glu Lys Leu Gln
                  50                  55                  60

 Glu Ile Arg Lys Tyr Tyr Met Ser Leu Lys Ser Glu Val Ala Thr
                  65                  70                  75

 His Arg Gln Glu Glu Lys Lys Ile Lys Lys Glu Arg Gln Gly Ser
                  80                  85                  90

 Val Ser Cys Gly Ser Leu His Val Ile Cys Phe Ile Arg His Trp
                  95                 100                 105

 Asn Glu Ser Leu Ile Ile Ile Ser Pro Thr Lys Cys Thr Cys Cys
                 110                 115                 120

 Arg Met Gln Val Ile Asn Ile Phe Ser Thr Phe Pro Ala Val Cys
                 125                 130                 135

 Cys His Gly His Lys Ser Pro Asn Pro Glu Leu Gln Pro Gln Lys
                 140                 145                 150

 Ala Leu Asn Trp Phe Asp Ile Ala Lys Tyr Ile Leu Tyr Thr Phe
                 155                 160                 165

 Pro Gly Trp Ile Val Ser Ile Pro Leu Ser Leu Leu Phe Phe Leu
                 170                 175                 180

 Leu Gln Lys Ile Ser
                 185

<210> 4786
<211> 1880
<212> DNA
<213> Homo sapien

<400> 4786
 agccgagagg tgtcaccccc agcgggcgcg ggccggagca cgggcaccca 50

 gcatgggggt actgctcaca cagaggacgc tgctcagtct ggtccttgca 100

 ctcctgtttc caagcatggc gagcatggcg gctataggca gctgctcgaa 150

 agagtaccgc gtgctccttg gccagctcca gaagcagaca gatctcatgc 200

 aggacaccag cagactcctg gacccctata tacgtatcca aggcctggat 250

 gttcctaaac tgagagagca ctgcagggag cgccccgggg ccttccccag 300

 tgaggagacc ctgagggggc tgggcaggcg gggcttcctg cagaccctca 350

 atgccacact gggctgcgtc ctgcacagac tggccgactt agagcagcgc 400

 ctccccaagg cccaggattt ggagaggtct gggctgaaca tcgaggactt 450

 ggagaagctg cagatggcga ggccgaacat cctcgggctc aggaacaaca 500

 tctactgcat ggcccagctg ctggacaact cagacacggc tgagcccacg 550

 aaggctggcc ggggggcctc tcagccgccc acccccaccc ctgcctcgga 600

 tgcttttcag cgcaagctgg agggctgcag gttcctgcat ggctaccatc 650

 gcttcatgca ctcagtgggg cgggtcttca gcaagtgggg ggagagcccg 700

 aaccggagcc ggagacacag cccccaccag gccctgagga agggggtgcg 750

 caggaccaga ccctccagga aaggcaagag actcatgacc aggggacagc 800

 tgccccggta gcctcgagag caccccttgc cggtgaagga tgcggcaggt 850

 gctctgtgga tgagaggaac catcgcagga tgacagctcc cgggtcccca 900

 aacctgttcc cctctgctac tagccactga gaagtgcact ttaagaggtg 950

 ggagctgggc agacccctct acctcctcca ggctgggaga cagagtcagg 1000

 ctgttgcgct cccacctcag ccccaagttc cccaggccca gtggggtggc 1050

 cgggcgggcc acgcgggacc gactttccat tgattcaggg gtctgatgac 1100

 acaggctgac tcatggccgg gctgactgcc cccctgcctt gctccccgag 1150

 gcctgccggt ccttccctct catgacttgc agggccgttg cccccagact 1200

 tcctcctttc cgtgtttctg aaggggaggt cacagcctga gctggcctcc 1250

 tatgcctcat catgtcccaa accagacacc tggatgtctg ggtgacctca 1300

 ctttaggcag ctgtaacagc ggcagggtgt cccaggagcc ctgatccggg 1350

 ggtccaggga atggagctca ggtcccaggc cagccccgaa gtcgccacgt 1400

 ggcctggggc aggtcacttt acctctgtgg acctgttttc tctttgtgaa 1450

 gctagggagt tagaggctgt acaaggcccc cactgcctgt cggttgcttg 1500

 gattccctga cgtaaggtgg atattaaaaa tctgtaaatc aggacaggtg 1550

 gtgcaaatgg cgctgggagg tgtacacgga ggtctctgta aaagcagacc 1600

 cacctcccag cgccgggaag cccgtcttgg gtcctcgctg ctggctgctc 1650

 cccctggtgg tggatcctgg aattttctca cgcaggagcc attgctctcc 1700

 tagagggggt ctcagaaact gcgaggccag ttccttggag ggacatgact 1750

 aatttatcga tttttatcaa tttttatcag ttttatattt ataagcctta 1800

 tttatgatgt atatttaatg ttaatattgt gcaaacttat atttaaaact 1850

 tgcctggttt ctaaaaaaaa aaaaaaaaaa 1880

<210> 4787
<211> 252
<212> PRT
<213> Homo sapien

<400> 4787
 Met Gly Val Leu Leu Thr Gln Arg Thr Leu Leu Ser Leu Val Leu
   1               5                  10                  15

 Ala Leu Leu Phe Pro Ser Met Ala Ser Met Ala Ala Ile Gly Ser
                  20                  25                  30

 Cys Ser Lys Glu Tyr Arg Val Leu Leu Gly Gln Leu Gln Lys Gln
                  35                  40                  45

 Thr Asp Leu Met Gln Asp Thr Ser Arg Leu Leu Asp Pro Tyr Ile
                  50                  55                  60

 Arg Ile Gln Gly Leu Asp Val Pro Lys Leu Arg Glu His Cys Arg
                  65                  70                  75

 Glu Arg Pro Gly Ala Phe Pro Ser Glu Glu Thr Leu Arg Gly Leu
                  80                  85                  90

 Gly Arg Arg Gly Phe Leu Gln Thr Leu Asn Ala Thr Leu Gly Cys
                  95                 100                 105

 Val Leu His Arg Leu Ala Asp Leu Glu Gln Arg Leu Pro Lys Ala
                 110                 115                 120

 Gln Asp Leu Glu Arg Ser Gly Leu Asn Ile Glu Asp Leu Glu Lys
                 125                 130                 135

 Leu Gln Met Ala Arg Pro Asn Ile Leu Gly Leu Arg Asn Asn Ile
                 140                 145                 150

 Tyr Cys Met Ala Gln Leu Leu Asp Asn Ser Asp Thr Ala Glu Pro
                 155                 160                 165

 Thr Lys Ala Gly Arg Gly Ala Ser Gln Pro Pro Thr Pro Thr Pro
                 170                 175                 180

 Ala Ser Asp Ala Phe Gln Arg Lys Leu Glu Gly Cys Arg Phe Leu
                 185                 190                 195

 His Gly Tyr His Arg Phe Met His Ser Val Gly Arg Val Phe Ser
                 200                 205                 210

 Lys Trp Gly Glu Ser Pro Asn Arg Ser Arg Arg His Ser Pro His
                 215                 220                 225

 Gln Ala Leu Arg Lys Gly Val Arg Arg Thr Arg Pro Ser Arg Lys
                 230                 235                 240

 Gly Lys Arg Leu Met Thr Arg Gly Gln Leu Pro Arg
                 245                 250

<210> 4788
<211> 3255
<212> DNA
<213> Homo sapien

<400> 4788
 cttgttcaaa gtcacacaac tgttaggcag aaatgaggtc attcaaatcc 50

 ttaatcttct cctccagacc acactgcctc ccaggaagag atgtgggcac 100

 ctcctgctct tgccaggcag gaaaccgctc cttatcaatg tctacggggt 150

 ctgctctcac acccaggaag gactgtgaca agcatggact aacctgcggc 200

 tccactcagc ctgctgtcag caccctcctg ttcagcagga tgcaacatct 250

 gatgttctgc caggaggctg tagagctgca catagaagta gccagtgttt 300

 cttcccattc caaaatggaa atatcactca gcctttttta aaattgactt 350

 cctatgttca ttttgattgt aggtgatgca gcaagcctca gggctgggga 400

 ttttcaaaat cttgttggct gactattata gatggccttg gaatttgctc 450

 ttgggggtct gaatataacg taggaaaatg tcctttctca gggagtgggg 500

 ctttaaagtt cgtttgttcg tcactccaat tttagctgtg cactgcacct 550

 ttctttgcac ccctactctc ttcatcttgt ctcatagcca cagctattga 600

 atttggcctg tgatcataag ttgggtttct gatctgatct cttgcattct 650

 ggtgggtact gggggcagaa tcagctttgt taatgatttt ctgggcagaa 700

 ggtaaattca gctgcatctg aaggggcttc acagtccaat agccgtcctt 750

 ttgttttaca taacagagag tgatggtcaa ggccacccac atctttagtg 800

 gtagagccag gacaaaaagt caggttttct gcctcttaag tctcatgctg 850

 cctcacatag cacctccaga gctctaggga aaggaggctc agagagatga 900

 agtgacttgt ctgaagtcct gtggctagtg gcagagaagt tggaattaga 950

 cctgcattgg acctcaattc gctgagcagt tgcagggaaa tctggaaatc 1000

 cttttttttt ttttttgaga cagagtctta ctctgtcacc caggctggag 1050

 tgcaatggcg tgatctcagc tcactgcaac accgcctccc gggttcaagc 1100

 gattctcctg cctcagcctc ctgagtagct gggattacag acgcacgcca 1150

 ccatgcccgg ctaatttttg tatttttagt agagacaagg tttccccata 1200

 ttggtcaggc tggtcttgaa ctcctgacct tgtgatccgc ccgccttgac 1250

 ctcccaaagt gctgggatga caggcgtgat ccaccgtgcc cagccgggaa 1300

 atccattttt taaaataaat tcaattatgt cttgaatgta ctcagaaaac 1350

 gagctgttta aaatgtccca ttgtgactgt aatgtgaaca atgacctcta 1400

 acttgtattt tatttggcaa ggatggggga tgtgcatcaa atcttcacct 1450

 ctgggatttc ctgaggcttg gtctacttgg ctcaccctcc acctgcatcc 1500

 ccaccccact cctagatatt aatacaaatc tagccttgac accgcctact 1550

 gctccaccac cgcctacgtt tttggccatc agagccttgg agtttacaga 1600

 gcagaggcca tgacattggg gagcttgttt aaaaatcaat gatcagaacc 1650

 ccacatttta gtttcctttt ggggagaaag aggagggccg tggaagaaaa 1700

 ggggtgtgca gctggagcgt tattatgtct ttctcagcgg caggcatgcc 1750

 cgcctctcca ccttctcccc gccaggcaca ggagccagca gctggagcgt 1800

 gctctgagtt tcaggggacc ccccacccag actgactggg gcttctggga 1850

 cttctcatag gaagagtcaa gacctcctgc gcttctttaa aaggtgatgg 1900

 gctcagtgtt cccagtggca tctggaggtg aagccggtac tgtctcagga 1950

 gtggaaggca atggcccact ggcctttttc tcccccacgt cacagtcccc 2000

 atttgctgga gcccttgagg gggccaccga aactgtggct ctcattcagc 2050

 ctcccaaagt gttgcactac tgaatactcc tttctgttta caccagcagt 2100

 gaatagagtc atgaaaagaa catattatat gcaatggctt gatgcttagt 2150

 gtggcaatca aaagcttgcc tgggcagatg taggcagggg ctagacaata 2200

 gtcatggagt tgtcaccagg tcactgtctc tctccttccc cttccaggtc 2250

 tctactgtcc cctgcagcca ccacaagggc taagctgttg aatgagcccc 2300

 ttggtttttc cttataaacg caatgactta cttgtgattc ttggtctaat 2350

 cccaggctaa gaaacaaaac aaaagcttgt gatctgaccc attcctttgc 2400

 tgccttcctt ctctttcagg cacctggacg tatttagtat tctgccctgt 2450

 gccttgccca ggggagggag aagtttctag caaatgtggc tttctgtctg 2500

 ctgcctggtg cttttatagt acttcatctg ctttttattg ttgttgttgt 2550

 gttttttaac caaaatggca tttgtttggc tgtcattgtc gagtatatat 2600

 ttattgtgtt ttacaaacat gagtatatat gtatgtatat gtataaaacc 2650

 aaacttatat atataagaag tcaaggcatg tatactagat attttaaaga 2700

 gttatttatc aagggaaaaa gatgtgtgtt ataaagtaaa cagagtctat 2750

 attttctata taatgtagat agtcaaacat agcttataaa ttataggagg 2800

 ttttggtttt cttttttatt attaaaggaa aaaaagaaga aaaaaaaaag 2850

 acaatgaatg caactgttct tagtgttttt aaggccaaac tactgtggaa 2900

 gctgggaggc ggccctccct gcgggcctcc agcagccctg tgcctgccgc 2950

 taggagctcc agagctgatg cccgttgtga tctctgcgat gctcgatgct 3000

 cggagccagc ggtcagcatc actcagccag ctggcctgtg ccgctctgac 3050

 gtggcttcca gctgttctcc gcaatttgca ttggtgggat aaaggaatga 3100

 aaaggataaa taaagattta aaagaaaaaa aaaaaaaaaa aaaaaaaaaa 3150

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3250

 aaaaa 3255

<210> 4789
<211> 133
<212> PRT
<213> Homo sapien

<400> 4789
 Met Asn Ala Thr Val Leu Ser Val Phe Lys Ala Lys Leu Leu Trp
   1               5                  10                  15

 Lys Leu Gly Gly Gly Pro Pro Cys Gly Pro Pro Ala Ala Leu Cys
                  20                  25                  30

 Leu Pro Leu Gly Ala Pro Glu Leu Met Pro Val Val Ile Ser Ala
                  35                  40                  45

 Met Leu Asp Ala Arg Ser Gln Arg Ser Ala Ser Leu Ser Gln Leu
                  50                  55                  60

 Ala Cys Ala Ala Leu Thr Trp Leu Pro Ala Val Leu Arg Asn Leu
                  65                  70                  75

 His Trp Trp Asp Lys Gly Met Lys Arg Ile Asn Lys Asp Leu Lys
                  80                  85                  90

 Glu Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
                  95                 100                 105

 Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
                 110                 115                 120

 Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys Lys
                 125                 130

<210> 4790
<211> 6476
<212> DNA
<213> Homo sapien

<400> 4790
 ctgggaagga aggagacgcc taaaccgcgg cactgcccgg tttgagcgta 50

 gccaaacctg cccaccggct ttgtagcccc gattctctgt gttttgctcc 100

 cgtctccgac gagagaggcg gcgacggtgg cgtctgcgac gggagacagc 150

 gcgtcggagc gagagagcgc tgcgcctgcc gccgccccaa cagcggaggc 200

 gccgccgcca tcggtcgtca ccagaccgga gccgcaggcc ctcccgagcc 250

 cggccatccg tgccccgctc ccagatctct atccttttgg gaccatgcgc 300

 ggaggaggct ttggggaccg ggaccgggat cgtgaccgtg gaggatttgg 350

 agcaagaggt ggtggtggcc ttcccccgaa gaaatttggt aatcctgggg 400

 agcgtttgcg taaaaaaaag tgggatttga gtgagctccc caagtttgag 450

 aaaaattttt atgtggaaca tccggaagta gcaaggctga caccatatga 500

 ggttgatgag ctacgccgaa agaaggagat tacagtgagg gggggagatg 550

 tttgtcctaa acccgtgttt gccttccatc atgctaactt cccacaatat 600

 gtaatggatg tgttgatgga tcagcacttt acagaaccaa ctccaattca 650

 gtgccaggga tttccgttgg ctcttagtgg ccgggatatg gtgggcattg 700

 ctcagactgg ctctgggaag acgttggcgt atctcctgcc tgcaattgtt 750

 catattaacc accagccata cttggaaagg ggagatggcc caatctgtct 800

 agttctggct cctaccagag agcttgccca gcaagtacag caggtggccg 850

 atgactatgg caaatgttct agattgaaga gtacttgtat ttatggaggt 900

 gctcctaaag gtccccagat tcgagacttg gaaagaggtg ttgagatctg 950

 catagccact cctggacgtc tgatagattt cctggagtca ggaaagacaa 1000

 atcttcgccg atgtacttac cttgtattgg acgaagctga cagaatgctt 1050

 gatatggggt ttgaacccca gatccgtaaa attgttgacc aaatcaggcc 1100

 tgataggcag acactgatgt ggagtgcaac ctggccaaaa gaagtaagac 1150

 agcttgcaga ggatttcctt cgtgattaca cccagatcaa cgtaggcaat 1200

 ctggagttga gtgccaacca caacatcctc cagatagtgg atgtctgcat 1250

 ggaaagtgaa aaagaccaca agttgatcca actaatggaa gaaataatgg 1300

 ctgaaaagga aaacaaaaca ataatatttg tggagacaaa gagacgctgt 1350

 gatgatctga ctcgaaggat gcgcagagat ggttggccag ctatgtgtat 1400

 ccatggagac aagagtcaac cagaaagaga ttgggtactt aatgagttcc 1450

 gttctggaaa ggcacccatc cttattgcta cagatgtagc ctcccgtggg 1500

 ctaggtttgt atagataggt gtctctgtca atggtatatg tatcttttgg 1550

 tttaaagatt cgtcatttca aattcagact tcaagtttag aaagttgtat 1600

 atacatgtgg ttagataaat atttgaaaga aaaaaataca aagcgtgatt 1650

 ctccccattc cctgcccccc ccacaatttt ttttaacttt ggtttccccc 1700

 accccccttt tattttcaaa gtctcttcct gctcctaaca aacaggcttt 1750

 ggtctgcagc aaggcctagg catgactatt caaacagagg gagaggagac 1800

 agacagctga atggctcagc ttctctctgg tggtggtttc tggctggata 1850

 gaataagcct gacgaaacct agctattgta agctagtttc ttcagttatt 1900

 cttttcccta tccctgtcta agctagatat atacagagag gtccagtttt 1950

 atgaatgctt attagatgga attttataag tctaatgcag tatcagaata 2000

 gcaaatatgt gtattgccca gtttaattta ctgaggtcaa attatcatgg 2050

 gcacttggct atcccctcct acccatgcac ttatctgtag gtgtgttatc 2100

 aactgatgat tttctggagt ttttgaccca ttaccattta agatatacag 2150

 agaattttat ggtagtttag cccactattc tgagctaaac aggtctaact 2200

 cagaacttct atattttaaa aaaaaagatt atttgtatta caaggaaatc 2250

 cttaaattat tgacaggtat ttaatttgcc cagtaaggtg agaagtacca 2300

 tattattccc ttatactata taatataaag agaacaggta ttcaaactgg 2350

 aatacaaaag taatgaagcc tttttatgca ttgcactcat cattccctcc 2400

 ttcagaggtg gtgacctgca gccatgatgg aaagttctct ctgcccctct 2450

 gccctctgag gtcatgtctg gatctgtgcc attagaactt gggcctgttg 2500

 ggagaggagg cggaggcctg aaggcagttt acataaagct ttcagtaatg 2550

 gttggttttt aaacaggctt gctatgtgct ggtagcttct ttgtgcatct 2600

 tgcctagaca attaaaaata tttgctccat gtccccttgc atttctaaac 2650

 caaattaatt ggctaccatt agaataactt agactcttca tcccaccccc 2700

 actcatccaa gtgaggggag agggaaggta cccgagtctg tttcttgtta 2750

 ctcaacatca gtgcttgttt tgggcccctt tgtttgctgc cttgtaaaaa 2800

 atcaaaagag ggagaaaacc caccaaaatg gcagaattct gaccaatgtc 2850

 ctacaagatc ctggaaagtg aaggcttcta cctcatagac aggggtgcaa 2900

 ttttcagctg agtcaccagg gccttttttc acttcctgtc aagcgatggt 2950

 ctcttaaatg ttcccttcag gtaagttctt tgattcccat aattttataa 3000

 tagtcatcct taggctacca cttccctttc cactgggata ttttttattt 3050

 ttcctttttt ttgtttgaac tacacactgt taaactaaaa gtattgaatt 3100

 tattttgttt tgttttttaa cagaagcttt gatatcagct gcagatcact 3150

 caatacatgg ccgagacaaa tctacattgg ccggaagcag ctctagatga 3200

 gcctcttggc tagacttagt ccctccttat tagtgattgg cgattcaggc 3250

 catgtcatag ggcctttcag acaaaaggtt cttatcccag tcagctggcc 3300

 aaaacattaa ctttggattt cttaccctgc tacagcatct tctagaaagg 3350

 cagcaagata atattgtggc agtgcacaga taacatcagg gtagacttga 3400

 ctggagaaaa ccaaattctg cgcttgctcc tgtgtgcccc catccagctg 3450

 tgcatgcaca cacaggacac ctttctagta tgaagaactt gcatcatgtc 3500

 tgccctctat tgagcacccc cttctagaaa tacttccaag tattagcatg 3550

 tgaactgttg actccaccct ggtgctttct gctaggaaag cacacttaac 3600

 gcatccagtg tagtaattga acttgttcta ctgccatggt catatgcagt 3650

 gggattgcat aaggagcatt atcctagctc tgaagatacc atggagtaga 3700

 attccccacc ccctgtctta catccaccct ggccctgtaa attctttttt 3750

 cctttgttgc gtcaacgacc ctagccggag actcaagctg ccccctgtga 3800

 taagtgcctt ctcgtctttc tggtgtgatt caggacttta ggggtcagta 3850

 aagaccgagg agcctttatt gtaataagaa acagacataa tgccccttct 3900

 tcacaagccc tgtaacaaca gctaattttt tttttttgat ctcccctttc 3950

 tcccttgaaa ttaatccagt ctgggcaata gatgcagtct gaccctttgg 4000

 atgtaactta catttttttt tattaattat ttttttctac aatcacccca 4050

 attatccttg ggggaggcgt tggaggacct gaaattttta cccgaaccca 4100

 ggttctccgg cgcttggcaa ccaaatgggg ctacagagaa gcatctaagc 4150

 cagttcacag agcgagcgtg tgtggggact tctcactgcc acggaccctt 4200

 gatgcatgct ccccgcgctc cagtggtccc gtgtcagaag gcggagtttt 4250

 cgaaaggagg ccgccaaaaa taaaaggcaa agagacggga tcggctgcag 4300

 cggtttccca aaggaggagg gagtgtgcat cggtctggta acaaacagag 4350

 aatgtttttt aattatttat atcacaaaaa tctgtgtttt atctaggata 4400

 ttttctgaat attctttgta aaatgcagat ttttttccac aaaacagtag 4450

 gattctttgt tatattctta aaattgtttg tttaagtagg taaaaatata 4500

 cattcagctg aaagcattac actaacattt acattttaag ccttaggagg 4550

 ttattcagcc caattcccag cagtagagag aatactaaac ttgtgtctca 4600

 aggtttcatg gttttcccac gttctttggc tattaattta atttcccagg 4650

 tcacgtagac aatcattgat aattgaaaca agtcctgagt tgaaataacc 4700

 ttgagttgag caaaaatatc ctcattttgg cagaagctgg gcttggtagt 4750

 acagtaaaat tttagtgtaa tgtgctcttg taattgaaag gggatagata 4800

 atctggatgt ttctgcaaag gaaaataggt gtgtacttaa cagctttggc 4850

 tctactcagt ttcttaaaaa gataagagca aaaaaagtta aatgttaatc 4900

 aaaacattta agtttccttt aaattgtagt aataaaatat atgaagctcc 4950

 tttttttact ttgctctgtg actggtttaa aggtaagttt gttatgttgt 5000

 tggtagattt tgccaggctt ctcccaacag agtagaagtg atttggcctc 5050

 ataacttcac agtggtttac cactttgttc tatgttctgg ttttgtaaag 5100

 gatagtactg gaatttgcgt ctgaagacca atattggtgt aactcctgtc 5150

 agtatattgg taaaatgtag cagaggcagg agtttggatg tttggatggg 5200

 attcccttag gattctacag ccaataaaga tcctatttcc tatgcatgtc 5250

 ccaggaatca gtaatcctct tttactctgt tgggatgagt ctttttttgt 5300

 ttctgttcag agtggttact aacttcacct tctttcctct tgctgtcatc 5350

 tgcattcgtg cttcccacct gttgttggca tgtcctttac cttctctttc 5400

 cctgccacat caacctacac actgactcat cattgacgtg gaagatgtgg 5450

 aagatgtcaa gtttgtgatc aactatgact atccaaacag ctcagaggat 5500

 tatgtgcacc gtattggccg aacagcccgt agcaccaaca agggtaccgc 5550

 ctataccttc ttcaccccag ggaacctaaa acaggccaga gagcttatca 5600

 aagtgctgga agaggccaat caggctatca atccaaaact gatgcagctt 5650

 gtggaccaca gaggaggcgg cggaggcggg ggtggtcgtt ctcgttaccg 5700

 gaccacttct tcagccaaca atcccaatct gatgtatcag gatgagtgtg 5750

 accgaaggct tcgaggagtc aaggatggtg gccggagaga ctctgcaagc 5800

 tatcgggatc gtagtgaaac cgatagagct ggttatgcta atggcagtgg 5850

 ctatggaagt ccaaattctg cctttggagc acaagcaggc caatacacct 5900

 atggtcaagg cacctatggg gcagctgctt atggcaccag tagctataca 5950

 gctcaagaat atggtgctgg cacttatgga gctagtagca ccacctcaac 6000

 tgggagaagt tcacagagct ctagccagca gtttagtggg ataggccggt 6050

 ctgggcagca gccacagcca ctgatgtcac aacagtttgc acagcctccg 6100

 ggagctacca atatgatagg ttacatgggg cagactgcct accaataccc 6150

 tcctcctcct ccccctcctc ctccttcacg taaatgaaac cactcaagtg 6200

 gtagtgactc cagcagactt aattacattt taaggaacac tgtctttcct 6250

 ttttttttcc tcttcgcctt ttcttttttt ttcctttttt cttttttttt 6300

 tttaattttt ccccccaacc atcgtgattt gtcttttcat gcagattagt 6350

 tagaattcac tgccaggttt cttctgccca ccaaaatgat ccagtctgga 6400

 ataacatttt gtaaaaaaaa aatatatata tatatatata aaaaaaaaaa 6450

 aaaaaaaaaa aaaaaaaaaa aaaaaa 6476

<210> 4791
<211> 505
<212> PRT
<213> Homo sapien

<400> 4791
 Trp Glu Gly Arg Arg Arg Leu Asn Arg Gly Thr Ala Arg Phe Glu
   1               5                  10                  15

 Arg Ser Pro Asn Leu Pro Thr Gly Phe Val Ala Pro Ile Leu Cys
                  20                  25                  30

 Val Leu Leu Pro Ser Pro Thr Arg Glu Ala Ala Thr Val Ala Ser
                  35                  40                  45

 Ala Thr Gly Asp Ser Ala Ser Glu Arg Glu Ser Ala Ala Pro Ala
                  50                  55                  60

 Ala Ala Pro Thr Ala Glu Ala Pro Pro Pro Ser Val Val Thr Arg
                  65                  70                  75

 Pro Glu Pro Gln Ala Leu Pro Ser Pro Ala Ile Arg Ala Pro Leu
                  80                  85                  90

 Pro Asp Leu Tyr Pro Phe Gly Thr Met Arg Gly Gly Gly Phe Gly
                  95                 100                 105

 Asp Arg Asp Arg Asp Arg Asp Arg Gly Gly Phe Gly Ala Arg Gly
                 110                 115                 120

 Gly Gly Gly Leu Pro Pro Lys Lys Phe Gly Asn Pro Gly Glu Arg
                 125                 130                 135

 Leu Arg Lys Lys Lys Trp Asp Leu Ser Glu Leu Pro Lys Phe Glu
                 140                 145                 150

 Lys Asn Phe Tyr Val Glu His Pro Glu Val Ala Arg Leu Thr Pro
                 155                 160                 165

 Tyr Glu Val Asp Glu Leu Arg Arg Lys Lys Glu Ile Thr Val Arg
                 170                 175                 180

 Gly Gly Asp Val Cys Pro Lys Pro Val Phe Ala Phe His His Ala
                 185                 190                 195

 Asn Phe Pro Gln Tyr Val Met Asp Val Leu Met Asp Gln His Phe
                 200                 205                 210

 Thr Glu Pro Thr Pro Ile Gln Cys Gln Gly Phe Pro Leu Ala Leu
                 215                 220                 225

 Ser Gly Arg Asp Met Val Gly Ile Ala Gln Thr Gly Ser Gly Lys
                 230                 235                 240

 Thr Leu Ala Tyr Leu Leu Pro Ala Ile Val His Ile Asn His Gln
                 245                 250                 255

 Pro Tyr Leu Glu Arg Gly Asp Gly Pro Ile Cys Leu Val Leu Ala
                 260                 265                 270

 Pro Thr Arg Glu Leu Ala Gln Gln Val Gln Gln Val Ala Asp Asp
                 275                 280                 285

 Tyr Gly Lys Cys Ser Arg Leu Lys Ser Thr Cys Ile Tyr Gly Gly
                 290                 295                 300

 Ala Pro Lys Gly Pro Gln Ile Arg Asp Leu Glu Arg Gly Val Glu
                 305                 310                 315

 Ile Cys Ile Ala Thr Pro Gly Arg Leu Ile Asp Phe Leu Glu Ser
                 320                 325                 330

 Gly Lys Thr Asn Leu Arg Arg Cys Thr Tyr Leu Val Leu Asp Glu
                 335                 340                 345

 Ala Asp Arg Met Leu Asp Met Gly Phe Glu Pro Gln Ile Arg Lys
                 350                 355                 360

 Ile Val Asp Gln Ile Arg Pro Asp Arg Gln Thr Leu Met Trp Ser
                 365                 370                 375

 Ala Thr Trp Pro Lys Glu Val Arg Gln Leu Ala Glu Asp Phe Leu
                 380                 385                 390

 Arg Asp Tyr Thr Gln Ile Asn Val Gly Asn Leu Glu Leu Ser Ala
                 395                 400                 405

 Asn His Asn Ile Leu Gln Ile Val Asp Val Cys Met Glu Ser Glu
                 410                 415                 420

 Lys Asp His Lys Leu Ile Gln Leu Met Glu Glu Ile Met Ala Glu
                 425                 430                 435

 Lys Glu Asn Lys Thr Ile Ile Phe Val Glu Thr Lys Arg Arg Cys
                 440                 445                 450

 Asp Asp Leu Thr Arg Arg Met Arg Arg Asp Gly Trp Pro Ala Met
                 455                 460                 465

 Cys Ile His Gly Asp Lys Ser Gln Pro Glu Arg Asp Trp Val Leu
                 470                 475                 480

 Asn Glu Phe Arg Ser Gly Lys Ala Pro Ile Leu Ile Ala Thr Asp
                 485                 490                 495

 Val Ala Ser Arg Gly Leu Gly Leu Tyr Arg
                 500                 505

<210> 4792
<211> 3000
<212> DNA
<213> Homo sapien

<400> 4792
 ggggggaaga atgagtagtc aggaactggt cactttgaat gtgggaggga 50

 agatattcac gacaaggttt tctacgataa agcagtttcc tgcttctcgt 100

 ttggcacgca tgttagatgg cagagaccaa gaattcaaga tggttggtgg 150

 ccagattttt gtagacagag atggtgattt gtttagtttc atcttagatt 200

 ttttgagaac tcaccagctt ttattaccca ctgaattttc agactatctt 250

 aggcttcaga gagaggctct tttctatgaa cttcgttctc tagttgatct 300

 cttaaaccca tacctgctac agccaagacc tgctcttgtg gaggtacatt 350

 tcctaagccg gaacactcaa gcttttttca gggtgtttgg ctcttgcagc 400

 aaaacaattg agatgctaac agggaggatt acagtgttta cagaacaacc 450

 ttcagcgccg acctggaatg gtaacttttt ccctcctcag atgaccttac 500

 ttccactgcc tccacaaaga ccttcttacc atgacctggt tttccagtgt 550

 ggttctgaca gcactactga taaccaaact ggagtcaggt attttgtact 600

 ttgcagtatt tctcttgtat accagtttgt gatgttttct ctaaaaactt 650

 gaagttcctc aggcctgtaa cttctggaaa agatgattat tcaaaataat 700

 gttttggggt aaccagtgga gttgggtaga atgaccaaat aattattttc 750

 caaactggga tactttttag agtgaaaggg gctattatta ggtgggacaa 800

 aaggaataaa tgaagactgc ccagaaaaaa ctgagactat ggacattcaa 850

 atcatgggag aaaataattt tgtagattat gttccattgc taatgaattt 900

 gacttagaaa agaattgcct tatttttaag agattgtttc agtggttcac 950

 ataaaggctc gctcactggt ttctcttgag ttccttacac actatataag 1000

 ttgttctttc agttttatga ttcaactact gtttttcctt cagctgactt 1050

 tatttttaaa cacccttaaa gacagatata tctcatggca aatttggtat 1100

 cctgttacag ccttggctct taaacaactc aaaatattgg gataggctgt 1150

 cagtatgtta aggatagttg ctcctgagtc aattcttcac ttactccctc 1200

 tgttgttctt ggctggatcc taacgctgat tttcactctg ctgtcacaaa 1250

 catttttccc cccgtaaaat gtcttaatgc tgtcctacca ttattttacc 1300

 aactgtgaaa gctggcttta atttttagga ggaaaagaaa agcctgcatg 1350

 tgttctttat tggtatcatt taaaatatac tttttttttt tggtaaaggt 1400

 aggcgtattt taagatattt tcttaacttg agcagtagcc aacaggaagg 1450

 ataccagtgt ctctctctct tagcgacaca ctccttggtc ttgcttacca 1500

 actggaggac actaggtaga atacccgagt atgacaattc ttaattgtta 1550

 acatttaata acttcctgtc cttcaaaaga gtttgaaatg tcattttggg 1600

 aaaagagagc cagtcaagct agtaggctga ttgtgaagaa aatctaatac 1650

 cttatcttta tctcaaacct ctgtacaact ttattttcat tgatgggata 1700

 ctttaacaaa aatgaaattt tttttggttt ttaaaatatg agtgattatg 1750

 acctctttgg ggatcatgct tcaaaaagtc agaaacctag agacaaaact 1800

 gtcattgatt tttaagaaga aacacactag gtcaaaagaa gatgtcctgg 1850

 aaatacgaag tactctttaa aaaccatgca tttggagaaa gtaattgttt 1900

 ccttgaaaaa tatgattaaa aactaaaact gggatgttcc tgtgtgtaca 1950

 cagtgccaaa tggttttccc tttttatgtt gtgttttaga aacagcacga 2000

 aagttttttc cattttaaag tgagaaaaca ttatatttag acttccataa 2050

 ttccaaaatc agaagctatt tttaaaatta gcattttctt gcatcaccaa 2100

 atggtattca attgtttgaa gctcaaaatt tttaccattc cataaatgtt 2150

 tgtgaatttt tagacagtgc caatttaaaa gtagagatag ccaatctgaa 2200

 tacggtgaaa ttatggggat ctctggtgat tgggatgaaa actctggcct 2250

 taaaaggtcc acttttagta tataattgcc taattagcaa tcatttttat 2300

 tttttgctca ctccctggtc tgaatctatc tgtctattca gatatttttt 2350

 ggtaggtttg gaaaatggag aagtgagcct aattggtgcc taattgtctg 2400

 gtgtatcatt cactttattc agtttgttct atcaatatga tttacccctc 2450

 aaggttaacc tagcaggttg ctcagttatt atctctcaag gccacagtac 2500

 tagaaatact tggcttgcat ctttcagatg ccattcatgt tatcaagctc 2550

 aaattatagt tggtcacagg attctaaagt ctttatttga cttctccttt 2600

 ttgaactggc tcaaatggaa aagtgtagtt gcttttaaat gttaaaaata 2650

 agtttaaact ttatatttcc cattggtttc ccctattttg tcctttcttt 2700

 gtgtgcttga aatattttat ttttcagttt gtcctcatag ggaatcaagt 2750

 attttagcta ggtgatgtct tgcaagtacg ttccactttg ttacaatcta 2800

 ctatctgtat atactatttg tatcttaatt cttttatgag atgttctgta 2850

 acatttttct cactttgaca aatgttttta gactgtacag tcaagatctg 2900

 gcgcttgggg gtaagtggaa tgatttgcta atattgagaa tctgttgtat 2950

 caaacataat aaactttttt tgagatgtga aaaaaaaaaa aaaaaaaaaa 3000

<210> 4793
<211> 3585
<212> DNA
<213> Homo sapien

<400> 4793
 caagggactt accagtctgg attcagcagt ttcttttcta aaacccattt 50

 gggtgactca gcagccgcat ctgctacctg attttatcct ggagaataca 100

 gtgcaatatt tctctttgat tatttattcc tcttgattgt ggaattaatt 150

 tgattgcttg ctaatggtac tagtagtact cctttcagaa gaaaaaatgg 200

 agcgatttag gtgaccaaat attacataca taaatagcca catgaagttt 250

 tagacgtttg gacttgaagc ctcaaagatc aaccaaccag tccccttatt 300

 tagtaaataa ggaaattgag gctacacaca gaaaattgta ctacagatta 350

 ttactaataa cccagcttgc taaattaggc tatacctagg taatctctag 400

 aagacaactc tgacagactc tttaatattt acccctggtt ggaacaatat 450

 ttgaaatgtc ccagatattt ctatgctact tagatatttg tggcaaagca 500

 gaaagctttt tgactgtgaa ggcagaggtc agcactgggg gaaacttgct 550

 ggtggtctct cccacaacct tgcccagagt cctttccact aaggaggtga 600

 agagaacaga gaaagagatt tccatttctg ctgccagagc tggtatttgc 650

 ctgcctgatt ctctgtgttt cctgtttcac cgccaccctt tcaggagaga 700

 actacaccag ttcatcatga gggtcaggga agcaaaagct ctcagatgtg 750

 tccagggcgt tacttaagaa atgagtatgc agattctgga aggggtgtgg 800

 aaaaggtgat cctttacccc cacccaggaa aacctgcatt gtgctagcat 850

 ggaagaatca tgggctttgg aattaaaccc atttggtgga attaaaccca 900

 tttggtttca aatcccagtt atgacatctg ttaactttgc aaactcacaa 950

 aaattatttg aaattatctg agttttcatt ttctcacctt ccagaatggg 1000

 gataatgcct cctgcatcgg ttgttgtgag gtttcaatga gatgaaatat 1050

 gggaaagaag aggtactcac ctgatggtcc ctgctttcct ctgctaggcc 1100

 tgagtaggaa ctggaactct ctaagagcat tactcatact ttttttttct 1150

 tccaaggtag tttggaatgt gagtgcaagt tagttctgca catacagccc 1200

 ttctccaaat ggtggtttcc tttgaggtct tttacatgat tatttatgac 1250

 tagagacaaa cttaataaga actcaagagg attttaaatg gagagaactc 1300

 aagctgtaga gaaaggagga ggcaacagac aggatatgta ggggcttacc 1350

 tagagcctgg cacgacttct gagaagtcac ccagcagacc ggctagaggg 1400

 gatttgtgtg ccacactcta cttgccgggc tgccattaaa atagaaagat 1450

 ataaaactgg gtcaccaaaa aaaccaaacc tcaaggctat ccttccagag 1500

 cagtagaaat gagtcccaca gcctggtctt tgagcagagg ctgggaagat 1550

 aggatacatc actgtctgga taccttctct ttttaataga atatattccg 1600

 tatgattccc tttccacctt aatggaaata atagctctct cctgcctgaa 1650

 caaaagggat tccaggtagt attgtggcta agagattaca gcggacgatg 1700

 gaaggttcat tttttaggga aggtgttggg taggaagagt cacatttgac 1750

 agaattcata aataatgtgt cctgaagtca gaggatgact gcaaagaaac 1800

 acctcatgat tccattaaat ataaagagat aaggagcaag gaggaaaaaa 1850

 gagaaagaat tggtctttat ttttcttgct aagaactctc tggagtattg 1900

 aaagacattg aaattatccc taaaattgtc acaacttttg tgaatactgg 1950

 tatacggttg gaggtgtttt taaatcttta tttcctctct ttctttgttc 2000

 tagtgacttg tcttgcttta agattttttt taaagaattg ttttattcaa 2050

 catatatcaa gttcttatgg aatgccagtc atggtactag ccccttggga 2100

 tgtagtggtt gagtgtgttc aatggaaaca gccccagtat acaaagacag 2150

 ttcactctgg tgtgctgtag gattggaaag ggagtggtac cagatgaaaa 2200

 tgaaacccta aagaagactg ctgggccatg agttgcttcc tcctcctcca 2250

 ccttaaccct ctgattccag aattgcagtc attttcttct gccaaggaaa 2300

 tccattaaaa actgcagcca cactgcaatt tcctaatgta gaacaagata 2350

 taaagcaggc tttgagacaa caacctacct ttgtttactc tttccaagct 2400

 ggaagagtcc ttctcctcta gttgccccta ggtcactggc taatttattt 2450

 taaaatttag atggaactca tgtatagtta agtgcacaaa tcttagccgt 2500

 gcagatgggt aattttcaca tagctatttg cccacatccg tgcctctaag 2550

 atagagacat acactgtttt cagcacccca gaaagttccc acatgcccat 2600

 ggtgccattt tgtgaaaggt atttataagg cccttcaaat ttgtggcttc 2650

 ctttctcata cttctcaggt ataatgaaag ggggagaaaa accccaccat 2700

 caacacaaaa caaggctata aagactgtgc accttttaac aagtcaattt 2750

 gtagtcagtc cctgggcctg tctttttttt ttttaaattt tgaagctacc 2800

 tgaggtttag aattccttca gccctagctg cttttattct gctttttatt 2850

 taaacaaaaa gagggggagg atctgaagga aactagtttt ctgtacaaag 2900

 gctttgaggt ccatggacta tacttgtccc atttatcatc ccaggtggtg 2950

 ctttgaccct gccataccct ggctattaag ataaaaagat ttgtggacat 3000

 taaaattatg aatatgtcag taataatcca gcacacattg aaatattgac 3050

 acagattacc ataatttgtg caacatctta taaacaatgt catttccata 3100

 gtagtctaag gcttcaccag cctggcccac tgtatctaga ctttaggttc 3150

 attttaataa ttatgctttc cttctctgta tcatttggga agttgataaa 3200

 tatcacttcc ttagatacct tcattcagtg atatatctgg cttttacaat 3250

 taaattggaa aaggtaagtt tctctttggt gggttgagag ttggaccatc 3300

 aattctaatc tacaaaagga aattcatgat ttcactctga cgcctaggat 3350

 ctagccaagg ctggtctgca gtatcagatg tccaaactca tctactatta 3400

 gccatatttt gtgagtcgtt tgtctaaact ttgtcaaaaa tgcctttgcc 3450

 atgattttgt tgctatctgg atttcaaaca tggacagtta ggaagatgtg 3500

 cattgaagta ggaaaatttt gttcagattt gctgttattt attttttaaa 3550

 ttaaaaatgg aaatgtattt taaagtttaa aaaaa 3585

<210> 4794
<211> 44
<212> PRT
<213> Homo sapien

<400> 4794
 Lys Gly Leu Thr Ser Leu Asp Ser Ala Val Ser Phe Leu Lys Pro
   1               5                  10                  15

 Ile Trp Val Thr Gln Gln Pro His Leu Leu Pro Asp Phe Ile Leu
                  20                  25                  30

 Glu Asn Thr Val Gln Tyr Phe Ser Leu Ile Ile Tyr Ser Ser
                  35                  40

<210> 4795
<211> 2566
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 349-452
<223> Unknown base

<400> 4795
 aaagaaaaat ggaaatatgg taggcctgtg gtattcttaa aagctaagtc 50

 attagaacta tgcagatccc caagtttaaa agtacaaata cagcaccagt 100

 agttagcttt ctagctgggg gagaagacag gagatttttc ttccacagat 150

 gtttattttg cttcctgata ggtactgcag caaagccatg ttgatgtgta 200

 gatgcatgat tcaaatttgt gcctcagtaa aattataaat tattgcatgt 250

 cataccttga ataatggaaa cggcaaacat taaacctgtg attacccata 300

 atgtacttta ataataaaaa acatggcagc caggtgcagt agagtgcann 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 450

 nnttaaagga cagaggctaa gctgtaaggt tagcatggtt ctgcctgggc 500

 ttgcttctgt gcttctgtgc aggctgagct gtaaggttag catggttctg 550

 cctgggcttt gcttctgcgc ttctgtgcag gctgagctgt aaggttagca 600

 tggttctgcc tgggctttgc ttctgcgctt ctgtgcaggc tgagctgtaa 650

 ggttagcatg gttctgcctg ggctttgctt ctgcgcttct gtgctagcag 700

 gtgcccacaa aatgtctttt tgaatttctt aatttttggg ttctggatgc 750

 aattcgtgca cgccaagaaa ctacttgctt gtcagtattt taattctgta 800

 gtacatgtgt gtgaatatca gccagtactt acagtaggag gatgaacaga 850

 aaaactgaga agacctgtct ttcaaaagat gggtttatcc actttttaag 900

 ggaaaaagtg acagtttggc atgggatttg aaaagtggaa attgtggaaa 950

 aattgagctg ttgaagtccc acatataacc agatttaata aagcttcaca 1000

 tgtgaattag ctccatatgt gtgtagaagg ttgcttttat agcaggtcct 1050

 taagtactcc ttttgaaatt cctccttttt tttttaagtc ataccattac 1100

 ttctttggat atgaatgtcc caagtggtat ctcctactgt agtatgagga 1150

 agaatggctg ttaatgtatt ttttgaattt tggtcttgtc ttggcctgga 1200

 tcatatccag tcaccactat gcaacaaatg atgtgcactg ggcaaggata 1250

 tgatgggtta tgaaagctgt atcttgtttg ttttttcttt tgcagtactc 1300

 caagtggtct aaacaggaat gtcttgtaaa acctcaagac tccctattga 1350

 ttattccctt acatatttat ttacaattta tcagggtaat tggtggtgcc 1400

 ttatgaaaag tataactcga tttcttgatc tttgagcatg ttttgtgttt 1450

 cttgtgtttt ctaaaagaat attagatatg gttaattgca ttacatctaa 1500

 aagatttaaa aaattgtgtg tatgctcagg ttccccacac ccatacccac 1550

 cctaacccct gtcatttaca ttggtggcaa ctttaaatgg taaccaagca 1600

 aaagtacatt ttgataatga gtattgataa tcctgaggaa aactagtgag 1650

 tatatgggag ccacctttga cctgtgccaa agcagtttct aatttcattt 1700

 gctaactata aaataaagaa ctgagccaaa ataatttgat cagtggtgtg 1750

 attagcctat tatcattgct gagaatagtg tttttggagt gtgaagtgat 1800

 tcctgaagat ttcacctgcc ttctgtttcc agcaagaatc cagtgatgac 1850

 caacacattt cctcactttt ggttcttgag aagtttatcc ctttgcaaca 1900

 aaccattaat agggaaaaca aggaaatgct ttccctttct ctttggcttc 1950

 ttaaagctca caaccaattc agaccccaag ttacttcaga gaagcaaatg 2000

 gcaccttttc cccattgcca aggatcccag cttatgcaga tatgaaggac 2050

 ggatcatttc tgaaaatgtt aagactctgc ttgcagtgga cttggcctca 2100

 gtttcatgaa atgtgtaact ctgtatgtgt atgttaggag gagggttggt 2150

 tgaaagagcg ggggcaggga ggggaatctg attacctctt gggaaataat 2200

 tttcttgcca acaaaaagat acacttgaag tttcttaagg tggcaagtcc 2250

 attaaaaaaa aaaattgtgt tggaccctcc cagtttagat caagtatttc 2300

 ttgggggtct tgctattgtg gttgatacca ataaatggaa gatccagaat 2350

 attttcattt aaagctcaac cattaattgg aacatggtga aacattgtac 2400

 acattgtaaa agtagggaac agtacaaaag aatggaatca aatactatat 2450

 tatgtgaata aactagagtg attttggaat ttcactctct tcaccccttc 2500

 tcacttgtat gttctgtaaa gtgtatttct actttggtag gaagaaagac 2550

 ttgatttaat atttca 2566

<210> 4796
<211> 87
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 349-452
<223> Unknown amino acid

<400> 4796
 Met Thr Asn Thr Phe Pro His Phe Trp Phe Leu Arg Ser Leu Ser
   1               5                  10                  15

 Leu Cys Asn Lys Pro Leu Ile Gly Lys Thr Arg Lys Cys Phe Pro
                  20                  25                  30

 Phe Leu Phe Gly Phe Leu Lys Leu Thr Thr Asn Ser Asp Pro Lys
                  35                  40                  45

 Leu Leu Gln Arg Ser Lys Trp His Leu Phe Pro Ile Ala Lys Asp
                  50                  55                  60

 Pro Ser Leu Cys Arg Tyr Glu Gly Arg Ile Ile Ser Glu Asn Val
                  65                  70                  75

 Lys Thr Leu Leu Ala Val Asp Leu Ala Ser Val Ser
                  80                  85

<210> 4797
<211> 1871
<212> DNA
<213> Homo sapien

<400> 4797
 ctgatgttgg gcagatcagt gaaggatgct gttgtgctcc agtcactgac 50

 atttttcata gaacattacc ccaaaggaca cagaaatgat tccaaaaaat 100

 gtagaagtct ttgcctagta ggtcactgca aagtgctaaa atctgaagaa 150

 aggaagagca gttcataaat gcttatcttc acattgttca ttgggctgcc 200

 ctaacctccc ctgctcccag agaatgccag atggctttac aattgaggtg 250

 gttcaaacac agaaggccct ttttcctttt attaattgct cagctatgtg 300

 tacattggcc cccacacctg ccacctgacc agcgcggctt ctgcctccct 350

 cagcactgcc agccgggggt tttcttagac tcatcccctg ggccaccttc 400

 cgctcctctc cctccctctg cattaacatc caggccaccc tcattactcc 450

 ttggcaacct agcttgggtt ggcctcccca gccagccttc cagactattc 500

 tttctctccc ttgcagcctg tcttgcacac cactgtggcc aggtcagtct 550

 ttctgagaat accatttcct cacatcatgg ccctgtttac aaagcagttt 600

 cccatttgcc tatcacatca gatcaaatca gaactcttcg gctctggatt 650

 gaagccgacg ccactgttcc tggcaagcct cattgccctc cgatcccggc 700

 gttggcctcc gtccctgtca ggtcttgtac gatgctgctc tctgccatcc 750

 tgccgtctcc agctctgcct gcatattggt cctgcattgc tctccacctc 800

 acagactctt attccacggc tctggccagt ccaaagcata catggcccag 850

 ttagttccct tttacttgaa atattccctg aggagccccc aggtattttt 900

 ccttactcac tggagacttg tagtcagggc cacactgatg tcatttggga 950

 attatttgca aagtcacaga tctggacttc tctctccagc taaatcatga 1000

 gttcctcagc taaatcacgg gcccacagtt ctgcagcagc tggtaaacac 1050

 ttttagtcac ggaaggaagc ctttttcggt tctcagctct gccaaggaac 1100

 ttatttcacg tacacaaaac cacaaaccgt gagaggattg ctgcctgtat 1150

 cctgttcccc ctcatctttt tttttctttg aaaagatggt aaagctgatt 1200

 ataagaattt aaataacgtg gccctagaac tacactctga ctctgatccg 1250

 cgtgtcctgc ccacagcacc aggccacgaa gacagaccat gtcgctatcc 1300

 tcacatttgc ttgtaactta ggaggcttgc cagtaaaatc gatactaaca 1350

 gtggacgtac ttctctttga ataagtttat tctatttcct tctcccattt 1400

 tctttatttg ttgaaaagaa tgatgctgat tgagaagcca aatattgtta 1450

 accattttcc ccgtctggca cggttctttt gcacagcact ggattaggcc 1500

 aggggactgg cctaaccctg caaatatcag gaaaggactc ttctagggaa 1550

 agtcgtacta atttgaattg atcactagaa atacatggtc tccacctaaa 1600

 agatgctttg tcacttaaaa ggctgagtag tcatcataat gtaaagaaac 1650

 ctctattgtc atgcaaccat ttgcacccag acattgtgcc tggttggcac 1700

 ttaacatttt atcacttgat tctcacacca cccttgcaat gtgatgaaac 1750

 caaggctcct aggtgctaag tgacattccc ctagtcacgc agcctagtgc 1800

 tagtcacgca gcctagtggt agagcgagga ttcaaaccca gttttgtttt 1850

 cctttgagct ggagctgcaa g 1871

<210> 4798
<211> 207
<212> PRT
<213> Homo sapien

<400> 4798
 Met Ala Leu Gln Leu Arg Trp Phe Lys His Arg Arg Pro Phe Phe
   1               5                  10                  15

 Leu Leu Leu Ile Ala Gln Leu Cys Val His Trp Pro Pro His Leu
                  20                  25                  30

 Pro Pro Asp Gln Arg Gly Phe Cys Leu Pro Gln His Cys Gln Pro
                  35                  40                  45

 Gly Val Phe Leu Asp Ser Ser Pro Gly Pro Pro Ser Ala Pro Leu
                  50                  55                  60

 Pro Pro Ser Ala Leu Thr Ser Arg Pro Pro Ser Leu Leu Leu Gly
                  65                  70                  75

 Asn Leu Ala Trp Val Gly Leu Pro Ser Gln Pro Ser Arg Leu Phe
                  80                  85                  90

 Phe Leu Ser Leu Ala Ala Cys Leu Ala His His Cys Gly Gln Val
                  95                 100                 105

 Ser Leu Ser Glu Asn Thr Ile Ser Ser His His Gly Pro Val Tyr
                 110                 115                 120

 Lys Ala Val Ser His Leu Pro Ile Thr Ser Asp Gln Ile Arg Thr
                 125                 130                 135

 Leu Arg Leu Trp Ile Glu Ala Asp Ala Thr Val Pro Gly Lys Pro
                 140                 145                 150

 His Cys Pro Pro Ile Pro Ala Leu Ala Ser Val Pro Val Arg Ser
                 155                 160                 165

 Cys Thr Met Leu Leu Ser Ala Ile Leu Pro Ser Pro Ala Leu Pro
                 170                 175                 180

 Ala Tyr Trp Ser Cys Ile Ala Leu His Leu Thr Asp Ser Tyr Ser
                 185                 190                 195

 Thr Ala Leu Ala Ser Pro Lys His Thr Trp Pro Ser
                 200                 205

<210> 4799
<211> 1263
<212> DNA
<213> Homo sapien

<400> 4799
 gctgtggacg aagaggcggc ctcggtggta agtggcggcc gctgggaccc 50

 agccaggtac cggtccggct cggccctgcc cctttccggc cgctctcact 100

 ccttccctcg gcctcgagtt cctcgtgggc ccgtgggggc cgccgcgggg 150

 tcggggctgc gaggcagcgc ccgccgttcc atggtaagcg gtgctacggg 200

 acgttcggaa ggaaacctcg ctagagcagg ggacgcctgg gctcctggct 250

 gaccacgggg cctttgcacg gccagggctt tgcgaccgca gtgtcttcct 300

 tctgtccccg gtcgtgcgcc gtgcccctca gcgcggctca cgtttcggaa 350

 cacgtctgcc tttcatgcct cccgaagagc ctccccgcat cccgtgcccc 400

 ctgctcgctg ctgccgctga cccttgggcg ctgcgctggt ccagagcgtg 450

 ttgtcctctg acgccgtcag aacctgagct ccctgcgagc tgggactccg 500

 ccgtgtcttc attgcctcca gtgcaaagca actgcttgca agagaacaaa 550

 agtgtgttca ggtgcacaga gtagaaaatt caaggagcct gaaagggtat 600

 ttggtgaaga cttgatgtgt ttttcccagt cctaacctcc aaggcccagt 650

 tctcccctgg ggcagaggga aacccgtttc ttacgggtct gcaaagaaag 700

 tctatgcagg aacatctacg tgcgtttctg caaaaggtca gttactttac 750

 ttggggctct tatacttaac gtagctcgga gagcgcccca tgcattcaga 800

 tacaggtggg attcctccgg aaacggagtt ttatagcacc agactttatc 850

 ccctttcctg tagaaattta gggtttttgc tgtcttttat aacgaacaat 900

 gctagcttga ctattgcttg tacaaaccgt tttttgccca agtcggacta 950

 ttttcttagg ttaaattcct tggtgcagaa gtgcgagggc tgtatttagg 1000

 cccctaaagg ggtggtacca aatcgccctc ccccaccagc ataagagggg 1050

 gccggcgaca cccttgccca agctggattt tgcagacctg gtaggcgtga 1100

 gatagtattt cactgtagct tgtgtttcct gtaagtatag tcgaacgtcg 1150

 tgatgttcct gttacatcta tgttacgttg atcattgtta ccactgacag 1200

 tcgtttcgag attggaaaat atgtttatta taaacgtttg actatttaaa 1250

 agccatttgt att 1263

<210> 4800
<211> 83
<212> PRT
<213> Homo sapien

<400> 4800
 Ala Val Asp Glu Glu Ala Ala Ser Val Val Ser Gly Gly Arg Trp
   1               5                  10                  15

 Asp Pro Ala Arg Tyr Arg Ser Gly Ser Ala Leu Pro Leu Ser Gly
                  20                  25                  30

 Arg Ser His Ser Phe Pro Arg Pro Arg Val Pro Arg Gly Pro Val
                  35                  40                  45

 Gly Ala Ala Ala Gly Ser Gly Leu Arg Gly Ser Ala Arg Arg Ser
                  50                  55                  60

 Met Val Ser Gly Ala Thr Gly Arg Ser Glu Gly Asn Leu Ala Arg
                  65                  70                  75

 Ala Gly Asp Ala Trp Ala Pro Gly
                  80

<210> 4801
<211> 1577
<212> DNA
<213> Homo sapien

<400> 4801
 ggaaactacg aggcaagaat atccaagaaa aatctagaaa agaagaaacc 50

 tgagtgagtc agcatgacca aatattaaaa catcttataa agctgcaata 100

 attaaaacaa tgtggtgctg atatgtggag ggtcaatgga acaagatgaa 150

 atggccaaaa ataaatttaa aatacatgtt gaaatgtatt aacagcatat 200

 gttaaagtta agttgtgtta actttatatg ttaaattcaa gttaattggt 250

 gaaagatgga ttattcaata tatgatgaac aactctgtca cgcagctaaa 300

 aaaaattaag ctaggtccat atgccagact agataccaaa ataaattcca 350

 ggaggaccaa gtttttaaaa gtaaaaatat ggaatcatgg aagtgcatga 400

 agaagaagta gcacttaaaa aaataataat ctcagcatgg ggaaggtcta 450

 agtatggccc tcaatcagaa accaggaagg aaaatattga ctattttaaa 500

 caaaattatc tctgtaccaa aaacagcata aaaggtcaag aaacaacaca 550

 ctggaaaaag aattgcaatg aatatcacag ccaaatagtt aatttcttat 600

 tttcaaaaaa tagcttctac aaatcgaaga gaaaaattct aaggtctcaa 650

 aggaaaaatg agcaaaggat ttgacaggtg gtagaataca gaaaaagaat 700

 ttaaaatagc tcctaaagat atggaaacat tactcatgat agcagaagta 750

 tcaattgaca aaattactca gattggtaac aaactttaag ggggaaagca 800

 cttccatgca ttgctgtaaa ttggtacatc ttctactgag aacaatccgg 850

 cagtagttaa caaaattgtg aatgcatata tctctttctc tagaaatttc 900

 tcttttggga atttattcta catatatatt caaacatgtg tgaaatactt 950

 ctatacaggt gattgaattt cactttattc ctaagagcag aagactgcaa 1000

 aatagtaaat atatacccaa aagggtctaa tggattagtt tttggcatat 1050

 cagcacatga taatactatg aagccataaa aaagagagat ctctatatgt 1100

 attgatgggg gaccatcttt aagatatact gtggtgttga acaaaacaac 1150

 atgctgaaaa tgtctcttat tcttttagaa tcaatataag tctgtgcttg 1200

 taaatgcagt aagtatcttt ggaagtatac ctaaaaattg gtaatagtgt 1250

 ttgactccag ggaagaacag atgggtgcca gagtgaaaaa aagatagctt 1300

 ttgcttttta tgacttttgg attctgtacc acgtaataat tttgatgtaa 1350

 attttgctgt gtgtgttttt acttgttcat gtagtgattt tataaattac 1400

 tcttttaatt ttctatcaat gaatatcctg ggataaaccc ctcatgatca 1450

 taatgaataa tgatgtgtgg agagtgggga gggtttacat atgaaaaatg 1500

 tagaaaatac aaaaagtgtc tatatataca aaaatgtaag tgttaacatt 1550

 tttatatttg cttcaagctt ttttttt 1577

<210> 4802
<211> 95
<212> PRT
<213> Homo sapien

<400> 4802
 Met Glu Val His Glu Glu Glu Val Ala Leu Lys Lys Ile Ile Ile
   1               5                  10                  15

 Ser Ala Trp Gly Arg Ser Lys Tyr Gly Pro Gln Ser Glu Thr Arg
                  20                  25                  30

 Lys Glu Asn Ile Asp Tyr Phe Lys Gln Asn Tyr Leu Cys Thr Lys
                  35                  40                  45

 Asn Ser Ile Lys Gly Gln Glu Thr Thr His Trp Lys Lys Asn Cys
                  50                  55                  60

 Asn Glu Tyr His Ser Gln Ile Val Asn Phe Leu Phe Ser Lys Asn
                  65                  70                  75

 Ser Phe Tyr Lys Ser Lys Arg Lys Ile Leu Arg Ser Gln Arg Lys
                  80                  85                  90

 Asn Glu Gln Arg Ile
                  95

<210> 4803
<211> 2276
<212> DNA
<213> Homo sapien

<400> 4803
 tggccttagg tgtacacaca cctggcactt tgcttgacac ataataggtg 50

 gaccacaaat atctactaaa tgaatatttg catatagtaa tattttaagg 100

 tactaaaagc agctcaaagt aaatatatta atatattaat tccattgcta 150

 tctggataac cactcaactt tcctgctgaa aatgcccatt taattaaaga 200

 aggttggata gagctctcta tatgcatttt ggacaggcag gggtttcagg 250

 tcataaacat tctgatgagt taatataaaa tgagagaaac tgtaaatttc 300

 cactactaaa aatcacaaaa ataacagaaa caaaagaaga gataagaatt 350

 tggggaattg tgctgaacaa tttagtggtt aaaaaaaaca actgtgcatg 400

 tttagactta aataagcccc catccaagtg tgaggggtcc agtaattttt 450

 caaaacatat gaaagtgtta atacattttg acaaaggacc attaaaaaag 500

 tcctgaattc tgacttgagg gaggaaagta atgactaata cattctctag 550

 agacttgcag actttgggaa ttcataaagg aatggatgat aattattaac 600

 tgttgctggc tgattgccca gacagttctc aacagccctg tacaagtctc 650

 tgggtttggg atggatcaat tctgagactg gaaaatggcc aaatctttgc 700

 aaatgagaaa tatttttctt ataagttctt attgtaggca aataattaca 750

 tagattattc atcagagaat ttttaaatgc tcataatctc aactctttca 800

 tttacaactt gtatttccaa tagtttatgg gtcatctctg catagatgtc 850

 agaagtcacc tcaagtttag tgtgtccaaa atctaactca caggtctgtt 900

 tctgacctcc caacttgctt tccttgtgtt tttcctatgc taatgatcca 950

 ccataatcaa aataattaac atttatccag tgcctactat gtactattcc 1000

 ctgtcctgtt ttacatttac tcatttaaag tccataagaa acattaaatc 1050

 tcatctgcct tctgaagaag atacaaccat gctctctttt acaaagtagg 1100

 aaactgggtc acagaaaggt gaagtcttta aggctgaatc acagtagctc 1150

 atcctagtaa atagaaaagc caggattcaa ctccaggggc tgggtgcaga 1200

 actgctattc ttcactgctt caccaatcag cagctaccca aggcagaaaa 1250

 ctttttcatc cttggctcct tcattctccc tgtcacccca gatcccctct 1300

 acatctagtc agagaatagg tcctgtcaat tccaacttct ctatatggct 1350

 cctctcaggc atgtgccctt aattggccta attctctaat acaccttccc 1400

 tctacatgct cactccctca gatcattgct ttatcacgtg ttacctgggt 1450

 tgctattaca taaagagcaa tctttctaaa atgaggatct tatcacttca 1500

 cttccacact aaaatgtttt tcctggggaa ccacactcct tagcaatctg 1550

 acccatcaga ccttccaggc tgtctcctgc ctgctcccta aggctccagc 1600

 cacacagaat tatcatgggc ccacacaccc accaaatcct cccatgcctt 1650

 tgcccatgtt gtctgggatg cccttctctc ccttctgtct acatcaagca 1700

 tcagactgaa tatccctctt gtgcggcctt ctaaaacctc ccgtccaaag 1750

 cgaaatatat tgccctctat ttatactttt acagcatttg gcacacaagt 1800

 acagagtagt agctttttat cacattctct gataattata tagatatggt 1850

 atttcttagc tctctctcca actggctaat aagttgcttt ttgtctgagt 1900

 gcctaatttt gtgttttgtg tctgagtgcc tcagttcctc aaaaaaaggt 1950

 tttttgatta gttcattatt catttgaaca tggaaattat gctcactagt 2000

 ggcaaatgcc actaaccgta ttccagaagc taggtgtcat gtttgcaata 2050

 agatatatta tcccttctac aagtcacctt ttatttcagg catttgtaaa 2100

 tgcccattaa taaagtatgg ttcataaatt ttaccttgta agtgcctaag 2150

 aaatgagact acaagctcca tttcagcagg acacaataaa tattatttta 2200

 taatgcaaaa aaatctatgt cggtgcggag aaagaggtaa tgaaatggca 2250

 ggaattcgat atcagctatc atacct 2276

<210> 4804
<211> 11
<212> PRT
<213> Homo sapien

<400> 4804
 Met Lys Trp Gln Glu Phe Asp Ile Ser Tyr His
   1               5                  10

<210> 4805
<211> 4526
<212> DNA
<213> Homo sapien

<400> 4805
 gaattccaca tgcacaccca cacccacgcg cgcccgcacc gccccacgcg 50

 cacacactcc tgcccacgcc cacgcagcgc tccgggaagt ccggtccggg 100

 cgagagcgcg aaaggatacc gagaagccac ccgcggagag cgcagcggcg 150

 ccctgggacg cggcgctctc ccggcgctgc tgcctcggct tggtctcggc 200

 ctgcgggccg tcggccggcg atggccctgg attatctact actgctcctc 250

 ctggcatccg cagtggctgc gatggaagaa acgttaatgg acaccagaac 300

 ggctactgca gagcctgggc tggacggcca atcctgcgtc cgggtgggaa 350

 gaagtcagtg gctacgatga aaacctgaac accatccgca cctaccaggt 400

 gtgcaatgtc ttcgagccca accagaacaa ttggctgctc accaccttca 450

 tcaaccggcg gggggcccat cgcatctaca cagagatgcg cttcactgtg 500

 agagactgca gcagcctccc taatgtccca ggatcctgca aggagacctt 550

 caacttgtat tactatgaga ctgactctgt cattgccacc aagaagtcag 600

 ccttctggtc tgaggccccc tacctcaaag tagacaccat tgctgcagat 650

 gagagcttct cccaggtgga ctttggggga aggctgatga aggtaaacac 700

 agaagtcagg agctttgggc ctcttactcg gaatggtttt tacctcgctt 750

 ttcaggatta tggagcctgt atgtctcttc tttctgtccg tgtcttcttc 800

 aaaaagtgtc ccagcattgt gcaaaatttt gcagtgtttc cagagactat 850

 gacaggggca gagagcacat ctctggtgat tgctcggggc acatgcatcc 900

 ccaacgcaga ggaagtggac gtgcccatca aactctactg caacggggat 950

 ggggaatgga tggtgcctat tgggcgatgc acctgcaagc ctggctatga 1000

 gcctgagaac agcgtggcat gcaaggcttg ccctgcaggg acattcaagg 1050

 ccagccagga agctgaaggc tgctcccact gcccctccaa cagccgctcc 1100

 cctgcagagg cgtctcccat ctgcacctgt cggaccggtt attaccgagc 1150

 ggactttgac cctccagaag tggcatgcac tagcgtccca tcaggtcccc 1200

 gcaatgttat ctccatcgtc aatgagacgt ccatcattct ggagtggcac 1250

 cctccaaggg agacaggtgg gcgggatgat gtgacctaca acatcatctg 1300

 caaaaagtgc cgggcagacc gccggagctg ctcccgctgt gacgacaatg 1350

 tggagtttgt gcccaggcag ctgggcctga cggagtgccg cgtctccatc 1400

 agcagcctgt gggcccacac cccctacacc tttgacatcc aggccatcaa 1450

 tggagtctcc agcaagagtc ccttcccccc acagcacgtc tctgtcaaca 1500

 tcaccacaaa ccaagccgcc ccctccaccg ttcccatcat gcaccaagtc 1550

 agtgccacta tgaggagcat caccttgtca tggccacagc cggagcagcc 1600

 caatggcatc atcctggact atgagatccg gtactatgag aaggaacaca 1650

 atgagttcaa ctcctccatg gccaggagtc agaccaacac agcaaggatt 1700

 gatgggctgc ggcctggcat ggtatatgtg gtacaggtgc gtgcccgcac 1750

 tgttgctggc tacggcaagt tcagtggcaa gatgtgcttc cagactctga 1800

 ctgacgatga ttacaagtca gagctgaggg agcagctgcc cctgattgct 1850

 ggctcggcag cggccggggt cgtgttcgtt gtgtccttgg tggccatctc 1900

 tatcgtctgt agcaggaaac gggcttatag caaagaggct gtgtacagcg 1950

 ataagctcca gcattacagc acaggccgag gctccccagg gatgaagatc 2000

 tacattgacc ccttcactta tgaggatccc aacgaagctg tccgggagtt 2050

 tgccaaggag attgatgtat cttttgtgaa aattgaagag gtcatcggag 2100

 caggggagtt tggagaagtg tacaaggggc gtttgaaact gccaggcaag 2150

 agggaaatct acgtggccat caagaccctg aaggcagggt actcggagaa 2200

 gcagcgtcgg gactttctga gtgaggcgag catcatgggc cagttcgacc 2250

 atcctaacat cattcgcctg gagggtgtgg tcaccaagag tcggcctgtc 2300

 atgatcatca cagagttcat ggagaatggt gcattggatt ctttcctcag 2350

 gcaaaatgac gggcagttca ccgtgatcca gcttgtgggt atgctcaggg 2400

 gcatcgctgc tggcatgaag tacctggctg agatgaatta tgtgcatcgg 2450

 gacctggctg ctaggaacat tctggtcaac agtaacctgg tgtgcaaggt 2500

 gtccgacttt ggcctctccc gctacctcca ggatgacacc tcagatccca 2550

 cctacaccag ctccttggga gggaagatcc ctgtgagatg gacagctcca 2600

 gaggccatcg cctaccgcaa gttcacttca gccagcgacg tttggagcta 2650

 tgggatcgtc atgtgggaag tcatgtcatt tggagagaga ccctattggg 2700

 atatgtccaa ccaagatgtc atcaatgcca tcgagcagga ctaccggctg 2750

 cccccaccca tggactgtcc agctgctcta caccagctca tgctggactg 2800

 ttggcagaag gaccggaaca gccggccccg gtttgcggag attgtcaaca 2850

 ccctagataa gatgatccgg aacccggcaa gtctcaagac tgtggcaacc 2900

 atcaccgccg tgccttccca gcccctgctc gaccgctcca tcccagactt 2950

 cacggccttt accaccgtgg atgactggct cagcgccatc aaaatggtcc 3000

 agtacaggga cagcttcctc actgctggct tcacctccct ccagctggtc 3050

 acccagatga catcagaaga cctcctgaga ataggcatca ccttggcagg 3100

 ccatcagaag aagatcctga acagcattca ttctatgagg gtccagataa 3150

 gtcagtcacc aacggcaatg gcatgagaac tcttgtttct tggggaagga 3200

 gaggagggaa aaggaccagg gtcaaggggg accagaggtt gaccactgtg 3250

 gaatgtactg gagagactgg cttctcagct gaggaatgca tttccatcag 3300

 tgaagaatca accggacctg ttgctagcag gcaatctcca tttctcagtg 3350

 acagaagcat gtttgagatg ccgtgggaaa ccaaatatat aataataaaa 3400

 atataaaaag gtgatgttca acagaagtga agacaaaaca atatgcatca 3450

 ggagaacaag agtaaaccca gctcccactc tcagtgggct gcagttgccc 3500

 aaccacagga agaaagggaa ggaggtagag ggaagaaaca gaagcagtgt 3550

 tccattttct tcctcaccaa tgacattctt ttcttttctc ctttcgtact 3600

 cctccctgag agtcccctcc cttctcccac actcgtttcc ctttgctcat 3650

 gactcctgta gggaagtttc ttcaaacaaa acccagctcc tgagtctcca 3700

 gatgttgttc tgtcagttgc caaaggactt tgctgaccac tgcatgggga 3750

 tccaaccaat tcaattaatg tcttcatatt gaagaagaga tgtaccttca 3800

 attgaaaacc tcgtttttct tttgtttgca ttttctgcaa aaaggaaaaa 3850

 gaaaccacaa attggggaaa aaaaaaagaa gaaaaacctg tttccgtgtg 3900

 caaaagcaca catatgtatg tctgtgttat aaaatgactg tgcttgttcg 3950

 taacagatgc aaacaagaaa gaagaactgg gaagtctttg tccctaggaa 4000

 atccaaaggg gctggaatat ggtgttggtt tggctttctg gttggcccaa 4050

 tcggcctatt ggctcaatgg gaagagagga gagggagaaa aataaaatga 4100

 aaggaaaaaa aaaagtttgc aaattcagac aggaaacagg tgagtggttt 4150

 gaattggatg cagtgtgggc catcctggaa tgatactgac tgattaatta 4200

 ttcctgataa catctcaaga aaaggagaag gaaagtgttt ctggagaatg 4250

 ttctttcaca tcactggaat ctgcaattca agaagtgaca agggagaatt 4300

 cttgctttac ctatggactg gcttaagccg tgtggcatcc gaggaatgtt 4350

 tcaaatgtgt ctgtgtttct ctttacattc cttgttgtac ctcattgttc 4400

 aattcacttt tgtaaattcc acctaacatt taattatttt aaatttctcc 4450

 ttttacctta atctccttgc taattttatc tgtctaatta aaaagagcag 4500

 aagcatgtct gggtttacgt aaaaaa 4526

<210> 4806
<211> 1057
<212> PRT
<213> Homo sapien

<400> 4806
 Glu Phe His Met His Thr His Thr His Ala Arg Pro His Arg Pro
   1               5                  10                  15

 Thr Arg Thr His Ser Cys Pro Arg Pro Arg Ser Ala Pro Gly Ser
                  20                  25                  30

 Pro Val Arg Ala Arg Ala Arg Lys Asp Thr Glu Lys Pro Pro Ala
                  35                  40                  45

 Glu Ser Ala Ala Ala Pro Trp Asp Ala Ala Leu Ser Arg Arg Cys
                  50                  55                  60

 Cys Leu Gly Leu Val Ser Ala Cys Gly Pro Ser Ala Gly Asp Gly
                  65                  70                  75

 Pro Gly Leu Ser Thr Thr Ala Pro Pro Gly Ile Arg Ser Gly Cys
                  80                  85                  90

 Asp Gly Arg Asn Val Asn Gly His Gln Asn Gly Tyr Cys Arg Ala
                  95                 100                 105

 Trp Ala Gly Arg Pro Ile Leu Arg Pro Gly Gly Lys Lys Ser Val
                 110                 115                 120

 Ala Thr Glu Asn Leu Asn Thr Ile Arg Thr Tyr Gln Val Cys Asn
                 125                 130                 135

 Val Phe Glu Pro Asn Gln Asn Asn Trp Leu Leu Thr Thr Phe Ile
                 140                 145                 150

 Asn Arg Arg Gly Ala His Arg Ile Tyr Thr Glu Met Arg Phe Thr
                 155                 160                 165

 Val Arg Asp Cys Ser Ser Leu Pro Asn Val Pro Gly Ser Cys Lys
                 170                 175                 180

 Glu Thr Phe Asn Leu Tyr Tyr Tyr Glu Thr Asp Ser Val Ile Ala
                 185                 190                 195

 Thr Lys Lys Ser Ala Phe Trp Ser Glu Ala Pro Tyr Leu Lys Val
                 200                 205                 210

 Asp Thr Ile Ala Ala Asp Glu Ser Phe Ser Gln Val Asp Phe Gly
                 215                 220                 225

 Gly Arg Leu Met Lys Val Asn Thr Glu Val Arg Ser Phe Gly Pro
                 230                 235                 240

 Leu Thr Arg Asn Gly Phe Tyr Leu Ala Phe Gln Asp Tyr Gly Ala
                 245                 250                 255

 Cys Met Ser Leu Leu Ser Val Arg Val Phe Phe Lys Lys Cys Pro
                 260                 265                 270

 Ser Ile Val Gln Asn Phe Ala Val Phe Pro Glu Thr Met Thr Gly
                 275                 280                 285

 Ala Glu Ser Thr Ser Leu Val Ile Ala Arg Gly Thr Cys Ile Pro
                 290                 295                 300

 Asn Ala Glu Glu Val Asp Val Pro Ile Lys Leu Tyr Cys Asn Gly
                 305                 310                 315

 Asp Gly Glu Trp Met Val Pro Ile Gly Arg Cys Thr Cys Lys Pro
                 320                 325                 330

 Gly Tyr Glu Pro Glu Asn Ser Val Ala Cys Lys Ala Cys Pro Ala
                 335                 340                 345

 Gly Thr Phe Lys Ala Ser Gln Glu Ala Glu Gly Cys Ser His Cys
                 350                 355                 360

 Pro Ser Asn Ser Arg Ser Pro Ala Glu Ala Ser Pro Ile Cys Thr
                 365                 370                 375

 Cys Arg Thr Gly Tyr Tyr Arg Ala Asp Phe Asp Pro Pro Glu Val
                 380                 385                 390

 Ala Cys Thr Ser Val Pro Ser Gly Pro Arg Asn Val Ile Ser Ile
                 395                 400                 405

 Val Asn Glu Thr Ser Ile Ile Leu Glu Trp His Pro Pro Arg Glu
                 410                 415                 420

 Thr Gly Gly Arg Asp Asp Val Thr Tyr Asn Ile Ile Cys Lys Lys
                 425                 430                 435

 Cys Arg Ala Asp Arg Arg Ser Cys Ser Arg Cys Asp Asp Asn Val
                 440                 445                 450

 Glu Phe Val Pro Arg Gln Leu Gly Leu Thr Glu Cys Arg Val Ser
                 455                 460                 465

 Ile Ser Ser Leu Trp Ala His Thr Pro Tyr Thr Phe Asp Ile Gln
                 470                 475                 480

 Ala Ile Asn Gly Val Ser Ser Lys Ser Pro Phe Pro Pro Gln His
                 485                 490                 495

 Val Ser Val Asn Ile Thr Thr Asn Gln Ala Ala Pro Ser Thr Val
                 500                 505                 510

 Pro Ile Met His Gln Val Ser Ala Thr Met Arg Ser Ile Thr Leu
                 515                 520                 525

 Ser Trp Pro Gln Pro Glu Gln Pro Asn Gly Ile Ile Leu Asp Tyr
                 530                 535                 540

 Glu Ile Arg Tyr Tyr Glu Lys Glu His Asn Glu Phe Asn Ser Ser
                 545                 550                 555

 Met Ala Arg Ser Gln Thr Asn Thr Ala Arg Ile Asp Gly Leu Arg
                 560                 565                 570

 Pro Gly Met Val Tyr Val Val Gln Val Arg Ala Arg Thr Val Ala
                 575                 580                 585

 Gly Tyr Gly Lys Phe Ser Gly Lys Met Cys Phe Gln Thr Leu Thr
                 590                 595                 600

 Asp Asp Asp Tyr Lys Ser Glu Leu Arg Glu Gln Leu Pro Leu Ile
                 605                 610                 615

 Ala Gly Ser Ala Ala Ala Gly Val Val Phe Val Val Ser Leu Val
                 620                 625                 630

 Ala Ile Ser Ile Val Cys Ser Arg Lys Arg Ala Tyr Ser Lys Glu
                 635                 640                 645

 Ala Val Tyr Ser Asp Lys Leu Gln His Tyr Ser Thr Gly Arg Gly
                 650                 655                 660

 Ser Pro Gly Met Lys Ile Tyr Ile Asp Pro Phe Thr Tyr Glu Asp
                 665                 670                 675

 Pro Asn Glu Ala Val Arg Glu Phe Ala Lys Glu Ile Asp Val Ser
                 680                 685                 690

 Phe Val Lys Ile Glu Glu Val Ile Gly Ala Gly Glu Phe Gly Glu
                 695                 700                 705

 Val Tyr Lys Gly Arg Leu Lys Leu Pro Gly Lys Arg Glu Ile Tyr
                 710                 715                 720

 Val Ala Ile Lys Thr Leu Lys Ala Gly Tyr Ser Glu Lys Gln Arg
                 725                 730                 735

 Arg Asp Phe Leu Ser Glu Ala Ser Ile Met Gly Gln Phe Asp His
                 740                 745                 750

 Pro Asn Ile Ile Arg Leu Glu Gly Val Val Thr Lys Ser Arg Pro
                 755                 760                 765

 Val Met Ile Ile Thr Glu Phe Met Glu Asn Gly Ala Leu Asp Ser
                 770                 775                 780

 Phe Leu Arg Gln Asn Asp Gly Gln Phe Thr Val Ile Gln Leu Val
                 785                 790                 795

 Gly Met Leu Arg Gly Ile Ala Ala Gly Met Lys Tyr Leu Ala Glu
                 800                 805                 810

 Met Asn Tyr Val His Arg Asp Leu Ala Ala Arg Asn Ile Leu Val
                 815                 820                 825

 Asn Ser Asn Leu Val Cys Lys Val Ser Asp Phe Gly Leu Ser Arg
                 830                 835                 840

 Tyr Leu Gln Asp Asp Thr Ser Asp Pro Thr Tyr Thr Ser Ser Leu
                 845                 850                 855

 Gly Gly Lys Ile Pro Val Arg Trp Thr Ala Pro Glu Ala Ile Ala
                 860                 865                 870

 Tyr Arg Lys Phe Thr Ser Ala Ser Asp Val Trp Ser Tyr Gly Ile
                 875                 880                 885

 Val Met Trp Glu Val Met Ser Phe Gly Glu Arg Pro Tyr Trp Asp
                 890                 895                 900

 Met Ser Asn Gln Asp Val Ile Asn Ala Ile Glu Gln Asp Tyr Arg
                 905                 910                 915

 Leu Pro Pro Pro Met Asp Cys Pro Ala Ala Leu His Gln Leu Met
                 920                 925                 930

 Leu Asp Cys Trp Gln Lys Asp Arg Asn Ser Arg Pro Arg Phe Ala
                 935                 940                 945

 Glu Ile Val Asn Thr Leu Asp Lys Met Ile Arg Asn Pro Ala Ser
                 950                 955                 960

 Leu Lys Thr Val Ala Thr Ile Thr Ala Val Pro Ser Gln Pro Leu
                 965                 970                 975

 Leu Asp Arg Ser Ile Pro Asp Phe Thr Ala Phe Thr Thr Val Asp
                 980                 985                 990

 Asp Trp Leu Ser Ala Ile Lys Met Val Gln Tyr Arg Asp Ser Phe
                 995                1000                1005

 Leu Thr Ala Gly Phe Thr Ser Leu Gln Leu Val Thr Gln Met Thr
                1010                1015                1020

 Ser Glu Asp Leu Leu Arg Ile Gly Ile Thr Leu Ala Gly His Gln
                1025                1030                1035

 Lys Lys Ile Leu Asn Ser Ile His Ser Met Arg Val Gln Ile Ser
                1040                1045                1050

 Gln Ser Pro Thr Ala Met Ala
                1055

<210> 4807
<211> 1030
<212> DNA
<213> Homo sapien

<400> 4807
 tgcgtcggag ggcggcggct gccgacggcg ggactgggtt ttctatcaga 50

 tgttccacgt aataatgctg gagttaagaa gtttccatta ttttgctcca 100

 aaccagaaga ctctgttccc tgtatataga ataggagtaa tatttgaaaa 150

 caactggctg atgtttaaaa ctgaagattg tcatgattgt ttatcctaat 200

 cccaatgctg aagtaagatt gtcttggaaa tactaagttg gggtaatcca 250

 aatctatttc tggaaccatg aaaattttgc tagtttttga ctttgacaat 300

 acaatcatag atgacaatag tgacacttgg attgtacaat gtgctcccaa 350

 caaaaagctt cctattgaac tacgtgattc ttatcgaaaa ggattttgga 400

 cagaatttat gggcagagtc tttaagtatt tgggagataa gggtgtaaga 450

 gaacatgaaa tgaaaagagc agtgacatca ttgcctttca ctccagggat 500

 ggtggaactc ttcaacttta taagaaagaa taaggataaa tttgactgca 550

 ttattatttc agattcaaat tcggtcttca tagattgggt tttagaagct 600

 gccagttttc atgacatatt tgataaagtg tttacaaatc cagcagcttt 650

 taatagcaat ggtcatctca ctgttgaaaa ttatcatact cattcttgca 700

 atagatgccc aaagaatctt tgcaaaaagg tagttttgat agaatttgta 750

 gataaacagt tacaacaggg agtgaattat acacaaattg tttatattgg 800

 tgatggtgga aatgatgtct gtccagtcac ctttttaaag aatgatgatg 850

 ttgccatgcc acggaaagga tataccttac agaaaactct ttccagaatg 900

 tctcaaaatc ttgagcctat ggaatattct gttgtagttt ggtcctcagg 950

 tgttgatata atttctcatt tacaatttct aataaaggat taatatgtcg 1000

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1030

<210> 4808
<211> 241
<212> PRT
<213> Homo sapien

<400> 4808
 Met Lys Ile Leu Leu Val Phe Asp Phe Asp Asn Thr Ile Ile Asp
   1               5                  10                  15

 Asp Asn Ser Asp Thr Trp Ile Val Gln Cys Ala Pro Asn Lys Lys
                  20                  25                  30

 Leu Pro Ile Glu Leu Arg Asp Ser Tyr Arg Lys Gly Phe Trp Thr
                  35                  40                  45

 Glu Phe Met Gly Arg Val Phe Lys Tyr Leu Gly Asp Lys Gly Val
                  50                  55                  60

 Arg Glu His Glu Met Lys Arg Ala Val Thr Ser Leu Pro Phe Thr
                  65                  70                  75

 Pro Gly Met Val Glu Leu Phe Asn Phe Ile Arg Lys Asn Lys Asp
                  80                  85                  90

 Lys Phe Asp Cys Ile Ile Ile Ser Asp Ser Asn Ser Val Phe Ile
                  95                 100                 105

 Asp Trp Val Leu Glu Ala Ala Ser Phe His Asp Ile Phe Asp Lys
                 110                 115                 120

 Val Phe Thr Asn Pro Ala Ala Phe Asn Ser Asn Gly His Leu Thr
                 125                 130                 135

 Val Glu Asn Tyr His Thr His Ser Cys Asn Arg Cys Pro Lys Asn
                 140                 145                 150

 Leu Cys Lys Lys Val Val Leu Ile Glu Phe Val Asp Lys Gln Leu
                 155                 160                 165

 Gln Gln Gly Val Asn Tyr Thr Gln Ile Val Tyr Ile Gly Asp Gly
                 170                 175                 180

 Gly Asn Asp Val Cys Pro Val Thr Phe Leu Lys Asn Asp Asp Val
                 185                 190                 195

 Ala Met Pro Arg Lys Gly Tyr Thr Leu Gln Lys Thr Leu Ser Arg
                 200                 205                 210

 Met Ser Gln Asn Leu Glu Pro Met Glu Tyr Ser Val Val Val Trp
                 215                 220                 225

 Ser Ser Gly Val Asp Ile Ile Ser His Leu Gln Phe Leu Ile Lys
                 230                 235                 240

 Asp


<210> 4809
<211> 1438
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 932, 934-937, 946, 951-952, 955
<223> Unknown base

<400> 4809
 ctctctctcc ctctcccttt cttttctaca ttgaaatctg ttcttacata 50

 atagagaaca gggctattga ataaagaccc aatcctacca gatctttagt 100

 tctaaagggc aacttgactg tgagtaggag ggcccccaag aaagggagga 150

 aagtccacac ccagctaacc acacaacagg gcttcattat ggaaatattt 200

 taacaaaagt acatgttatt accaaccaaa gagatgcatg tgcaatagaa 250

 gccttcctta aaaacaggct aaataacctc attttatgca gcagtttaat 300

 ctgagaacag agggaaaggt gtgcagtggt tccagagggg ccttatattc 350

 tatttttagt ctagatattt tttgtttata aattcccaag gaattgttaa 400

 cactttggtg acacctaatg gattcttttt gaaattccaa ggtgcttcag 450

 ttctttgccc aagtgaactg tgccttttat tgcatttctg ttcgtctctt 500

 ggtggctctt ctgacttttt ggagaatacc catcttgttg gaggcagact 550

 taagttgtta tgctgtgcca cacaatttac tgagacaatc atatcttcct 600

 aagcatttaa ggaaagttga aaaaaataga attagctata aaatatgtat 650

 ggcacatctt gtttaatttt gcatgtaact tctcttttgt acattgatga 700

 ggttttagtg acattgtcat ccaacacttt acctttattg ttcagggaat 750

 gccttcgtga ttttttgtac tggttttatt attcagacta tggcctggat 800

 ttgagtatat tgttattacc acctggtttt ttaattattc atcccagtaa 850

 acttatattt tgtgaagcat ttgtttctca gattaagaca ctgttagaac 900

 ctaaagtagt agctgatggg tatctgtgaa tntnnnnttt tttttntttt 950

 nnacntgaag tagattgtct gaataggcat cctcatctat atttacccaa 1000

 aacctcgctt actgtcatgt gcactacaaa ttgcaatttg gaaacctact 1050

 gtattgaaat tctgtcagtt tatggttctt gaagactgat gtcctttccc 1100

 aaacactggt tactgcagca gcatttttaa tgtgtaagtg aagaaaaaag 1150

 gccactaagg ccaaagattt tttaagaatc attgtacaaa tcattatgtt 1200

 aaactatcta agctttgctg taatactgtt ttctcttcaa tatgtgatgg 1250

 tacaggaagg atgttaaatg aaggggtggt attgcaggag agcattttaa 1300

 atggcagaag taaaaagtta taatatttat aattttgatg ggtttaagtt 1350

 tatttttgta gggaagattt ttctccccta aaatagtttc tagaatggca 1400

 aaagtgtttc cattattaaa aattgaagtt attagttg 1438

<210> 4810
<211> 94
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 932, 934-937, 946, 951-952, 955
<223> Unknown amino acid

<400> 4810
 Met Tyr Gly Thr Ser Cys Leu Ile Leu His Val Thr Ser Leu Leu
   1               5                  10                  15

 Tyr Ile Asp Glu Val Leu Val Thr Leu Ser Ser Asn Thr Leu Pro
                  20                  25                  30

 Leu Leu Phe Arg Glu Cys Leu Arg Asp Phe Leu Tyr Trp Phe Tyr
                  35                  40                  45

 Tyr Ser Asp Tyr Gly Leu Asp Leu Ser Ile Leu Leu Leu Pro Pro
                  50                  55                  60

 Gly Phe Leu Ile Ile His Pro Ser Lys Leu Ile Phe Cys Glu Ala
                  65                  70                  75

 Phe Val Ser Gln Ile Lys Thr Leu Leu Glu Pro Lys Val Val Ala
                  80                  85                  90

 Asp Gly Tyr Leu


<210> 4811
<211> 3653
<212> DNA
<213> Homo sapien

<400> 4811
 agcccagcat tcatggcgca gccatctctt gtacttgcta gcaaaacacc 50

 acctgtggaa agtcagctca aacttccaac ctcatccctc acaaaggggg 100

 aatggagggt ttggttttgg ctttcactgg agtctgcaac aagaactggc 150

 atcatgctgc ccatttcccg cctctcccca cccagacccc tgcctcaggg 200

 acgcctgtcc tcagcccagc cctcagctgc agccaggcct tcagcctccg 250

 taacccccgc tcagggtccc caccccctgc agccctgtcc ctccagatgc 300

 atggccttgt cctgtgtggg ggtggccgag agcactgccc cagccctggg 350

 taccttgggc aggaagctgg cagaggccag ggctgccatt caaacagggg 400

 caggtggttt tgccaggagg aagttgacag ttcaacttca aacatgggtg 450

 acgcaggccc cacactgcct gctccccgtc ccacccctcc ctgagacacg 500

 ccaccccgcc ctctccctct ctgagagcga gatacccggc cagacaccct 550

 cacctgcggt gcccagctgc ccaggctgag gcaagagaag gccagaaacc 600

 atgcccatgg ggtctctgca accgctggcc accttgtacc tgctggggat 650

 gctggtcgct tcctgcctcg gacggctcag ctggtatgac ccagatttcc 700

 aggcaaggct cacccgttcc aactcgaagt gccagggcca gctggaggtc 750

 tacctcaagg acggatggca catggtttgc agccagagct ggggccggag 800

 ctccaagcag tgggaggacc ccagtcaagc gtcaaaagtc tgccagcggc 850

 tgaactgtgg ggtgccctta agccttggcc ccttccttgt cacctacaca 900

 cctcagagct caatcatctg ctacggacaa ctgggctcct tctccaactg 950

 cagccacagc agaaatgaca tgtgtcactc tctgggcctg acctgcttag 1000

 aaccccagaa gacaacacct ccaacgacaa ggcccccgcc caccacaact 1050

 ccagagccca cagctcctcc caggctgcag ctggtggcac agtctggcgg 1100

 ccagcactgt gccggcgtgg tggagttcta cagcggcagc ctggggggta 1150

 ccatcagcta tgaggcccag gacaagaccc aggacctgga gaacttcctc 1200

 tgcaacaacc tccagtgtgg ctccttcttg aagcatctgc cagagactga 1250

 ggcaggcaga gcccaagacc taggggagcc acgggaacac cagcccttgc 1300

 caatccaatg gaagatccag aactcaagct gtacctccct ggagcattgc 1350

 ttcaggaaaa tcaagcccca gaaaagtggc cgagttcttg ccctcctttg 1400

 ctcaggtttc cagcccaagg tgcagagccg tctggtgggg ggcagcagca 1450

 tctgtgaagg caccgtggag gtgcgccagg gggctcagtg ggcagccctg 1500

 tgtgacagct cttcagccag gagctcgctg cggtgggagg aggtgtgccg 1550

 ggagcagcag tgtggcagcg tcaactccta tcgagtgctg gacgctggtg 1600

 acccaacatc ccgggggctc ttctgtcccc atcagaagct gtcccagtgc 1650

 cacgaacttt gggagagaaa ttcctactgc aagaaggtgt ttgtcacatg 1700

 ccaggatcca aaccccgcag gcctggccgc aggcacggtg gcaagcatca 1750

 tcctggccct ggtgctcctg gtggtgctgc tggtcgtgtg cggccccctt 1800

 gcctacaaga agctagtgaa gaaattccgc cagaagaagc agcgccagtg 1850

 gattggccca acgggaatga accaaaacat gtctttccat cgcaaccaca 1900

 cggcaaccgt ccgatcccat gctgagaacc ccacagcctc ccacgtggat 1950

 aacgaataca gccaacctcc caggaactcc cgcctgtcag cttatccagc 2000

 tctggaaggg gctctgcatc gctcctccat gcagcctgac aactcctccg 2050

 acagtgacta tgatctgcat ggggctcaga ggctgtaaag aactgggatc 2100

 catgagcaaa aagccgagag ccagacctgt ttgtcctgag aaaactgtcc 2150

 gctcttcact tgaaatcatg tccctatttc taccccggcc agaacatgga 2200

 cagaggccag aagccttccg gacaggcgct gctgccccga gtggcaggcc 2250

 agctcacact ctgctgcaca acagctcggc cgcccctcca cttgtggaag 2300

 ctgtggtggg cagagcccca aaacaagcag ccttccaact agagactcgg 2350

 gggtgtctga agggggcccc ctttccctgc ccgctgggga gcggcgtctc 2400

 agtgaaatcg gctttctcct cagactctgt ccctggtaag gagtgacaag 2450

 gaagctcaca gctgggcgag tgcattttga atagtttttt gtaagtagtg 2500

 cttttcctcc ttcctgacaa atcgagcgct ttggcctctt ctgtgcagca 2550

 tccacccctg cggatccctc tggggaggac aggaagggga ctcccggaga 2600

 cctctgcagc cgtggtggtc agaggctgct cacctgagca caaagacagc 2650

 tctgcacatt caccgcagct gccagccagg ggtctgggtg ggcaccaccc 2700

 tgacccacag cgtcacccca ctccctctgt cttatgactc ccctccccaa 2750

 ccccctcatc taaagacacc ttcctttcca ctggctgtca agcccacagg 2800

 gcaccagtgc cacccagggc cctgcacaaa ggggcgccta gtaaacctta 2850

 accaacttgg ttttttgctt cacccagcaa ttaaaagtcc caagctgagg 2900

 tagtttcagt ccatcacagt tcatcttcta acccaagagt cagagatggg 2950

 gctggtcatg ttcctttggt ttgaataact cccttgacga aaacagactc 3000

 ctctagtact tggagatctt ggacgttaca cctaatccca tggggcctcg 3050

 gcttccttaa ctgcaagtga gaagaggagg tctacccagg agcctcgggt 3100

 ctgatcaagg gagaggccag gcgcagctca ctgcggcggc tccctaagaa 3150

 ggtgaagcaa catgggaaca catcctaaga caggtccttt ctccacgcca 3200

 tttgatgctg tatctcctgg gagcacaggc atcaatggtc caagccgcat 3250

 aataagtctg gaagagcaaa agggagttac taggatatgg ggtgggctgc 3300

 tcccagaatc tgctcagctt tctgccccca ccaacaccct ccaaccaggc 3350

 cttgccttct gagagccccc gtggccaagc ccaggtcaca gatcttcccc 3400

 cgaccatgct gggaatccag aaacagggac cccatttgtc ttcccatatc 3450

 tggtggaggt gagggggctc ctcaaaaggg aactgagagg ctgctcttag 3500

 ggagggcaaa ggttcggggg cagccagtgt ctcccatcag tgcctttttt 3550

 aataaaagct ctttcatcta tagtttggcc accatacagt ggcctcaaag 3600

 caaccatggc ctacttaaaa accaaaccaa aaataaagag tttagttgag 3650

 gag 3653

<210> 4812
<211> 695
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 193
<223> unknown amino acid

<400> 4812
 Ser Pro Ala Phe Met Ala Gln Pro Ser Leu Val Leu Ala Ser Lys
   1               5                  10                  15

 Thr Pro Pro Val Glu Ser Gln Leu Lys Leu Pro Thr Ser Ser Leu
                  20                  25                  30

 Thr Lys Gly Glu Trp Arg Val Trp Phe Trp Leu Ser Leu Glu Ser
                  35                  40                  45

 Ala Thr Arg Thr Gly Ile Met Leu Pro Ile Ser Arg Leu Ser Pro
                  50                  55                  60

 Pro Arg Pro Leu Pro Gln Gly Arg Leu Ser Ser Ala Gln Pro Ser
                  65                  70                  75

 Ala Ala Ala Arg Pro Ser Ala Ser Val Thr Pro Ala Gln Gly Pro
                  80                  85                  90

 His Pro Leu Gln Pro Cys Pro Ser Arg Cys Met Ala Leu Ser Cys
                  95                 100                 105

 Val Gly Val Ala Glu Ser Thr Ala Pro Ala Leu Gly Thr Leu Gly
                 110                 115                 120

 Arg Lys Leu Ala Glu Ala Arg Ala Ala Ile Gln Thr Gly Ala Gly
                 125                 130                 135

 Gly Phe Ala Arg Arg Lys Leu Thr Val Gln Leu Gln Thr Trp Val
                 140                 145                 150

 Thr Gln Ala Pro His Cys Leu Leu Pro Val Pro Pro Leu Pro Glu
                 155                 160                 165

 Thr Arg His Pro Ala Leu Ser Leu Ser Glu Ser Glu Ile Pro Gly
                 170                 175                 180

 Gln Thr Pro Ser Pro Ala Val Pro Ser Cys Pro Gly Xaa Gly Lys
                 185                 190                 195

 Arg Arg Pro Glu Thr Met Pro Met Gly Ser Leu Gln Pro Leu Ala
                 200                 205                 210

 Thr Leu Tyr Leu Leu Gly Met Leu Val Ala Ser Cys Leu Gly Arg
                 215                 220                 225

 Leu Ser Trp Tyr Asp Pro Asp Phe Gln Ala Arg Leu Thr Arg Ser
                 230                 235                 240

 Asn Ser Lys Cys Gln Gly Gln Leu Glu Val Tyr Leu Lys Asp Gly
                 245                 250                 255

 Trp His Met Val Cys Ser Gln Ser Trp Gly Arg Ser Ser Lys Gln
                 260                 265                 270

 Trp Glu Asp Pro Ser Gln Ala Ser Lys Val Cys Gln Arg Leu Asn
                 275                 280                 285

 Cys Gly Val Pro Leu Ser Leu Gly Pro Phe Leu Val Thr Tyr Thr
                 290                 295                 300

 Pro Gln Ser Ser Ile Ile Cys Tyr Gly Gln Leu Gly Ser Phe Ser
                 305                 310                 315

 Asn Cys Ser His Ser Arg Asn Asp Met Cys His Ser Leu Gly Leu
                 320                 325                 330

 Thr Cys Leu Glu Pro Gln Lys Thr Thr Pro Pro Thr Thr Arg Pro
                 335                 340                 345

 Pro Pro Thr Thr Thr Pro Glu Pro Thr Ala Pro Pro Arg Leu Gln
                 350                 355                 360

 Leu Val Ala Gln Ser Gly Gly Gln His Cys Ala Gly Val Val Glu
                 365                 370                 375

 Phe Tyr Ser Gly Ser Leu Gly Gly Thr Ile Ser Tyr Glu Ala Gln
                 380                 385                 390

 Asp Lys Thr Gln Asp Leu Glu Asn Phe Leu Cys Asn Asn Leu Gln
                 395                 400                 405

 Cys Gly Ser Phe Leu Lys His Leu Pro Glu Thr Glu Ala Gly Arg
                 410                 415                 420

 Ala Gln Asp Leu Gly Glu Pro Arg Glu His Gln Pro Leu Pro Ile
                 425                 430                 435

 Gln Trp Lys Ile Gln Asn Ser Ser Cys Thr Ser Leu Glu His Cys
                 440                 445                 450

 Phe Arg Lys Ile Lys Pro Gln Lys Ser Gly Arg Val Leu Ala Leu
                 455                 460                 465

 Leu Cys Ser Gly Phe Gln Pro Lys Val Gln Ser Arg Leu Val Gly
                 470                 475                 480

 Gly Ser Ser Ile Cys Glu Gly Thr Val Glu Val Arg Gln Gly Ala
                 485                 490                 495

 Gln Trp Ala Ala Leu Cys Asp Ser Ser Ser Ala Arg Ser Ser Leu
                 500                 505                 510

 Arg Trp Glu Glu Val Cys Arg Glu Gln Gln Cys Gly Ser Val Asn
                 515                 520                 525

 Ser Tyr Arg Val Leu Asp Ala Gly Asp Pro Thr Ser Arg Gly Leu
                 530                 535                 540

 Phe Cys Pro His Gln Lys Leu Ser Gln Cys His Glu Leu Trp Glu
                 545                 550                 555

 Arg Asn Ser Tyr Cys Lys Lys Val Phe Val Thr Cys Gln Asp Pro
                 560                 565                 570

 Asn Pro Ala Gly Leu Ala Ala Gly Thr Val Ala Ser Ile Ile Leu
                 575                 580                 585

 Ala Leu Val Leu Leu Val Val Leu Leu Val Val Cys Gly Pro Leu
                 590                 595                 600

 Ala Tyr Lys Lys Leu Val Lys Lys Phe Arg Gln Lys Lys Gln Arg
                 605                 610                 615

 Gln Trp Ile Gly Pro Thr Gly Met Asn Gln Asn Met Ser Phe His
                 620                 625                 630

 Arg Asn His Thr Ala Thr Val Arg Ser His Ala Glu Asn Pro Thr
                 635                 640                 645

 Ala Ser His Val Asp Asn Glu Tyr Ser Gln Pro Pro Arg Asn Ser
                 650                 655                 660

 Arg Leu Ser Ala Tyr Pro Ala Leu Glu Gly Ala Leu His Arg Ser
                 665                 670                 675

 Ser Met Gln Pro Asp Asn Ser Ser Asp Ser Asp Tyr Asp Leu His
                 680                 685                 690

 Gly Ala Gln Arg Leu
                 695

<210> 4813
<211> 960
<212> DNA
<213> Homo sapien

<400> 4813
 tcctcccatt ctttcggtgt ttgacttggg tgttctccta tagaattaat 50

 acatactagg tatggtagaa ttcttatttt tagtcactgg ccttactgtt 100

 ccttaaacat ttcaagtttt tgccttaggg ccttggcatt tgctgatatc 150

 tctgtctgga acattcagcg cccaaataat caggtggttt gccccttctg 200

 tacccatagt taatgtacac agcttgctag cttactacat ttatgtcatg 250

 cttattcctt gaccctcccc acccaaatgg tgccccccct tccatcactc 300

 tcctcttacc cttctttatt tctcttcaca gcatttgtca gtactttaca 350

 ttattccata ctagaaggtg agtgtcagtt ctattagaac aggaacttgg 400

 tcttattccc tcctatattt cggtgcccag aatagcactt ggcacacagt 450

 cttttgagtg agtggatgac cttgtgcaca atcagttatt atcattgaac 500

 ttcggtaaag cattaattgt ggcatctttg tcagatgttt agataagatg 550

 gttggcgtac gcatagtctg catgttgtat ttttagtctt tgaagatatg 600

 aagtcaggta agcaacatcc taacatagtc tatttcttga catctcttac 650

 aaacgtagag tatagcctat cctcaggtgt gtgctgaagt ttatattagg 700

 gcttttgggt accttagaat gtgggtattg caatctttat tcaggatgtt 750

 atcagtcact ggtacagtta gtcttgttat taaaagaaaa aagaaaaaaa 800

 aacaggtaga agttggaatt agccttcgta ggaaggattc cagatgcaaa 850

 tgcaggaaaa actctgttgt ccttggaaac tactctggag agagttattg 900

 gcactataat tcccaaacct accctgttaa aagattctgt ggaaatgggt 950

 taacctttat 960

<210> 4814
<211> 80
<212> PRT
<213> Homo sapien

<400> 4814
 Met Trp Val Leu Gln Ser Leu Phe Arg Met Leu Ser Val Thr Gly
   1               5                  10                  15

 Thr Val Ser Leu Val Ile Lys Arg Lys Lys Lys Lys Lys Gln Val
                  20                  25                  30

 Glu Val Gly Ile Ser Leu Arg Arg Lys Asp Ser Arg Cys Lys Cys
                  35                  40                  45

 Arg Lys Asn Ser Val Val Leu Gly Asn Tyr Ser Gly Glu Ser Tyr
                  50                  55                  60

 Trp His Tyr Asn Ser Gln Thr Tyr Pro Val Lys Arg Phe Cys Gly
                  65                  70                  75

 Asn Gly Leu Thr Phe
                  80

<210> 4815
<211> 3254
<212> DNA
<213> Homo sapien

<400> 4815
 ggcggcggcc gcgcgctgct cggggcccga ctgcggcgcg agggcggcgc 50

 gggagcgacg ctggcccgga ccgaggaaac tatgccgcag acgtccgttg 100

 tcttctccag catccttggg cccagctgta gcggacaggt gcagcctggc 150

 atgggggagc gtggaggcgg ggccggtggc ggctccgggg acctcatctt 200

 ccaagatgga cacctcatct ctgggtccct ggaggccctg atggagcacc 250

 ttgttcccac ggtggactat taccccgata ggacgtacat cttcaccttt 300

 ctcctgagct cccgggtctt tatgccccct catgacctgc tggcccgcgt 350

 ggggcagatc tgcgtggagc agaagcagca gctggaagcc gggcctgaaa 400

 aggccaagct gaagtctttc tcagccaaga tcgtgcagct cctgaaggag 450

 tggaccgagg ccttccccta tgacttccag gatgagaagg ccatggccga 500

 gctgaaagcc atcacacacc gtgtcaccca gtgtgatgag gagaatggca 550

 cagtgaagaa ggccattgcc cagatgacac agagcctgtt gctgtccttg 600

 gctgcccgga gccagctcca ggaactgcga gagaagctcc ggccaccggc 650

 tgtagacaag gggcccatcc tcaagaccaa gccaccagcc gcccagaagg 700

 acatcctggg cgtgtgctgc gaccccctgg tgctggccca gcagctgact 750

 cacattgagc tggacagggt cagcagcatt taccctgagg acttgatgca 800

 gatcgtcagc cacatggact cattggacaa ccacaggtgc cgaggggacc 850

 tgaccaagac ctacagcctg gaggcctatg acaactggtt caactgcctg 900

 agcatgctgg tggccactga ggtgtgccgg gtggtgaaga agaaacaccg 950

 gacccgcatg ttggagttct tcattgatgt ggcccgggag tgcttcaaca 1000

 tcgggaactt caactccatg atggccatca tctctggcat gaacctcagt 1050

 cctgtggcaa ggctgaagaa aacttggtcc aaggtcaaga cagccaagtt 1100

 tgatgtcttg gagcatcaca tggacccgtc cagcaacttc tgcaactacc 1150

 gtacagccct gcagggggcc acgcagaggt cccagatggc caacagcagc 1200

 cgtgaaaaga tcgtcatccc tgtgttcaac ctcttcgtta aggacatcta 1250

 cttcctgcac aaaatccata ccaaccacct gcccaacggg cacattaact 1300

 ttaagaaatt ctgggagatc tccagacaga tccatgagtt catgacatgg 1350

 acacaggtag agtgtccttt cgagaaggac aagaagattc agagttacct 1400

 gctcacggcg cccatctaca gcgaggaagc tctcttcgtc gcctcctttg 1450

 aaagtgaggg tcccgagaac cacgtggaaa aagacagctg gaagaccctc 1500

 aggaccaccc ttctgaacag agcctgaggc ggatgcagcc cgcgacgcca 1550

 gaggaagcac gtgcactaac tgggtttaaa ttttgactga tgtgggttga 1600

 gatgaggagg cctcactggt tggggtccat tttgtatata acttttatga 1650

 gaaaaaaatg gtaattattt cacgcatcaa cctttggcac ttacaaagtt 1700

 ttttttgttt attttaaata acagggcagg gccctgcttt ggggaggggg 1750

 aggggagagt atcatgggag atggtatcca tgataacatc ttattctaat 1800

 gaaatgtaga tttttatttt ctacttttga ttattgacat cttatgaaaa 1850

 aaatatttta aaaaacccag ccaaaaccaa cgtgagccct gcctgctcgg 1900

 acgcctttcc agccagtgtc tctgacgtcg gggttagtgc cttagagggt 1950

 actggggtct ggtcttcctg ctctgtggtt tgggctgcgg tgagtcccac 2000

 tccacctggg cgcctgccct caggagcctg ggctgcgagg ctccatagga 2050

 gggctggtgg ctgggaggtc gcgtccgcac acttctggaa gtgagccttt 2100

 gagtacgggc tgtccaaagt ttacattttc attttccttt cagggatttg 2150

 cggggtcagg gaggggcagg gggcacctgg cagcatattt tctgtgacaa 2200

 tgtgtccagc aaatcattct tcaactacat tttagaaagg aggaaatcta 2250

 aaataaggta agggagggaa gcatggagtt gtcagttttc tgggctgtga 2300

 ctgaaagaca cactgagctg tgatgaagaa aaatacatgg ccgactccag 2350

 ggtggtgaca tttagagcta gtcttgaaac ctatcatcta cagaggggag 2400

 ggcagccaac agccctcttc ccacctgggt aggcagcgcc ctaattggaa 2450

 ttggaaacag aaaattcgcc aggccatact gctggagccc attcagataa 2500

 aactgcccaa atactgagag gtgttttcta cacccagcta gaggagcaca 2550

 ctccattttc ccatgtctga cttcgtggtg tgagccctgg gccctactga 2600

 ccatggcgca ggacagctgt ccttcagaaa gcacacggtc aatccacgtg 2650

 gaccgtctcc ctcgcaggaa ctccgcatcc ttgtccctct ctgcattccc 2700

 agtttccgca ggagccttga tcaatgggga agcctgggtg aggatgggcc 2750

 aggtcccaat tcccaaagct cctggaagag cctgaagaca ttgggaaagg 2800

 ctgggcctgg ggaggaggca gccctgggcc cgttgcccat gcctctggtc 2850

 ctgggtggag caggaatagt tccactgtat tgtcacagtg tgtttgcact 2900

 ttctgaggtt ctagctagta cagattgtat attgatagta catattgctt 2950

 tgtttatgtc tttgagatga gaaaggctta aaacttgaga atatatattt 3000

 ggaatacagc cttagaacgg tttctgtaca catccacgtg cacttcacgg 3050

 gtgatcagtt ctagtaccta cttgaaacag tgtctgtctg ctactttatt 3100

 ttcccaattt gatacatacc ctgatttgat gttttggtat ttgagatgaa 3150

 ctctgagtat gaagctgtac cataatgcag ggcgtcagtt ttggtgtgac 3200

 tggacatact tgcttcaata aaagaataca tcactcccaa aaaaaaaaaa 3250

 aaaa 3254

<210> 4816
<211> 428
<212> PRT
<213> Homo sapien

<400> 4816
 Met Glu His Leu Val Pro Thr Val Asp Tyr Tyr Pro Asp Arg Thr
   1               5                  10                  15

 Tyr Ile Phe Thr Phe Leu Leu Ser Ser Arg Val Phe Met Pro Pro
                  20                  25                  30

 His Asp Leu Leu Ala Arg Val Gly Gln Ile Cys Val Glu Gln Lys
                  35                  40                  45

 Gln Gln Leu Glu Ala Gly Pro Glu Lys Ala Lys Leu Lys Ser Phe
                  50                  55                  60

 Ser Ala Lys Ile Val Gln Leu Leu Lys Glu Trp Thr Glu Ala Phe
                  65                  70                  75

 Pro Tyr Asp Phe Gln Asp Glu Lys Ala Met Ala Glu Leu Lys Ala
                  80                  85                  90

 Ile Thr His Arg Val Thr Gln Cys Asp Glu Glu Asn Gly Thr Val
                  95                 100                 105

 Lys Lys Ala Ile Ala Gln Met Thr Gln Ser Leu Leu Leu Ser Leu
                 110                 115                 120

 Ala Ala Arg Ser Gln Leu Gln Glu Leu Arg Glu Lys Leu Arg Pro
                 125                 130                 135

 Pro Ala Val Asp Lys Gly Pro Ile Leu Lys Thr Lys Pro Pro Ala
                 140                 145                 150

 Ala Gln Lys Asp Ile Leu Gly Val Cys Cys Asp Pro Leu Val Leu
                 155                 160                 165

 Ala Gln Gln Leu Thr His Ile Glu Leu Asp Arg Val Ser Ser Ile
                 170                 175                 180

 Tyr Pro Glu Asp Leu Met Gln Ile Val Ser His Met Asp Ser Leu
                 185                 190                 195

 Asp Asn His Arg Cys Arg Gly Asp Leu Thr Lys Thr Tyr Ser Leu
                 200                 205                 210

 Glu Ala Tyr Asp Asn Trp Phe Asn Cys Leu Ser Met Leu Val Ala
                 215                 220                 225

 Thr Glu Val Cys Arg Val Val Lys Lys Lys His Arg Thr Arg Met
                 230                 235                 240

 Leu Glu Phe Phe Ile Asp Val Ala Arg Glu Cys Phe Asn Ile Gly
                 245                 250                 255

 Asn Phe Asn Ser Met Met Ala Ile Ile Ser Gly Met Asn Leu Ser
                 260                 265                 270

 Pro Val Ala Arg Leu Lys Lys Thr Trp Ser Lys Val Lys Thr Ala
                 275                 280                 285

 Lys Phe Asp Val Leu Glu His His Met Asp Pro Ser Ser Asn Phe
                 290                 295                 300

 Cys Asn Tyr Arg Thr Ala Leu Gln Gly Ala Thr Gln Arg Ser Gln
                 305                 310                 315

 Met Ala Asn Ser Ser Arg Glu Lys Ile Val Ile Pro Val Phe Asn
                 320                 325                 330

 Leu Phe Val Lys Asp Ile Tyr Phe Leu His Lys Ile His Thr Asn
                 335                 340                 345

 His Leu Pro Asn Gly His Ile Asn Phe Lys Lys Phe Trp Glu Ile
                 350                 355                 360

 Ser Arg Gln Ile His Glu Phe Met Thr Trp Thr Gln Val Glu Cys
                 365                 370                 375

 Pro Phe Glu Lys Asp Lys Lys Ile Gln Ser Tyr Leu Leu Thr Ala
                 380                 385                 390

 Pro Ile Tyr Ser Glu Glu Ala Leu Phe Val Ala Ser Phe Glu Ser
                 395                 400                 405

 Glu Gly Pro Glu Asn His Val Glu Lys Asp Ser Trp Lys Thr Leu
                 410                 415                 420

 Arg Thr Thr Leu Leu Asn Arg Ala
                 425

<210> 4817
<211> 667
<212> DNA
<213> Homo sapien

<400> 4817
 gtgttaggga atagcttctg gtcgggcatt tgattgagtg ctgtattctg 50

 acatttttca ggaaccaaat acatgtgatt catcttctat aaatatttgc 100

 agtttcttca agttgaaatg agaaaagctc gtaaattgag caccaggtct 150

 aataaatcat tcacttaccc aagaacagaa agacaggaaa agctagcatg 200

 ttaatctaat gaaaaaatcg aatgttaaaa aaccaagaaa gtagaagata 250

 tttgacatta actttctaat cattgataat aatctaataa tcataacatt 300

 attcttaaaa cctgaaagaa tggattcctg ctcccaatgt gtttttaata 350

 tcaacttaaa ctaaaataat ttttttacct atttttggaa gcttggaaat 400

 tgagatgtag ttgtctaatg ttaacctaat taagagagct tggtgtgatt 450

 tctcatatac agcatctaaa tatttaagtt ttaatgtctt ctaaaatatt 500

 attacattct tcatactata gttttttaac atcctttaga aaacttgtat 550

 cagcttcact ttcaaaccat gctggcatcg aactcaggtg tagtggtatc 600

 agaatgttat gaaataattt tttattttca ttataaactc catttttaca 650

 ataaacactt ctcaacc 667

<210> 4818
<211> 32
<212> PRT
<213> Homo sapien

<400> 4818
 Met Leu Ala Ser Asn Ser Gly Val Val Val Ser Glu Cys Tyr Glu
   1               5                  10                  15

 Ile Ile Phe Tyr Phe His Tyr Lys Leu His Phe Tyr Asn Lys His
                  20                  25                  30

 Phe Ser


<210> 4819
<211> 10174
<212> DNA
<213> Homo sapien

<400> 4819
 gactggggtt ttaaggggtg tggcaggagg ttttggactc gatgagtttc 50

 caccgaaatg tcggagaagt caggccagag cacaaaagca aaggatggga 100

 aaaagtatgc aacactcagt ttatttaata cttacaaggg gaaatcatta 150

 gaaacacaga aaaccacagc tcgacatgga ttacagagtc ttggaaaagt 200

 cggtatttca cggcgtatgc ctccacctgc taacctccca agtcttaaag 250

 cagaaaacaa aggcaatgat cctaatgtaa acattgtacc taaagatggc 300

 acagggtggg catcaaaaca agagcaacat gaagaagaaa aaacaccaga 350

 agtgccacca gcacagccaa aacctggggt tgcagctccc ccagaagtag 400

 cacctgctcc caaatcatgg gccagtaaca agcaaggtgg gcaaggagat 450

 ggaatccaag tgaatagtca gtttcagcaa gaatttccca gcctgcaggc 500

 agctggggat caggaaaaaa aagaaaagga aacaaatgat gacaactatg 550

 gacctggacc cagtttacgt ccaccaaatg ttgcttgttg gagagatggt 600

 ggtaaggctg ctggctcacc ttcgtcatct gatcaagatg aaaagctccc 650

 tggccaggat gaaagcacag ctggaacatc agagcaaaat gatatcctca 700

 aagtggtgga aaagaggata gcttgtggtc ctccacaggc taaactgaat 750

 ggacagcagg ctgctctcgc ttcccagtat agagctatga tgcctcctta 800

 tatgttccaa cagtatccga ggatgacata tcctcctcta catggtccca 850

 tgagattccc accttcttta tctgaaacaa acaaaggcct tcgaggaaga 900

 ggcccacctc cttcatgggc ctctgagcct gaacgcccat ccattcttag 950

 tgcatcagaa ctgaaggagc ttgataaatt tgataaccta gatgctgaag 1000

 ctgatgaagg ttgggcaggt gctcagatgg aagtagatta tacagagcaa 1050

 ctgaatttca gtgatgatga tgaacaagga agtaacagtc ctaaagagaa 1100

 taacagtgag gatcaaggtt caaaagcctc tgaaaacaac gaaaacaaaa 1150

 aagaaacaga tgaagtttcc aacactaaat catcttccca aatacctgcc 1200

 caaccatcag tagcaaaagt tccctatggg aaaggacctt catttaatca 1250

 ggaacgtgga acatcttcac atctgccacc acctccaaag ttgcttgcac 1300

 agcagcatcc acctccagat cgacaggcag tacctggaag accaggcccc 1350

 tttccctcca agcagcaagt agctgatgaa gatgaaatat ggaagcaaag 1400

 acgaagacaa caatcagaaa tttctgcagc agtagaacgt gctcgtaaac 1450

 ggcgtgaaga ggaagagcga agaatggaag aacaaaggaa ggcagcttgt 1500

 gcggagaaac tgaaacgatt ggatgagaag cttggcatcc tggaaaaaca 1550

 accatctcca gaggaaatta gggaaaggga gcgagaaaaa gaacgggagc 1600

 gtgagaaaga acttgaaaaa gaacaagaac aggagcgaga gaaggagagg 1650

 gaaaaagaca gagagagaca gcaggaaaag gagaaagagc tggagaagga 1700

 gcaggaaaaa caaagagaaa tggagaaaga aagaaagcaa gaaaaagaaa 1750

 aagaactaga acggcagaaa gaaaaggaaa aagaactaca aaagatgaaa 1800

 gaacaagaaa aggaatgtga gctggagaag gaaagggaaa aattagagga 1850

 gaaaattgaa cccagagaac ctaatttaga gcccatggta gaaaaacaag 1900

 aaagtgaaaa cagctgtaat aaagaggagg aacccgtttt cactagacaa 1950

 gacagcaatc gcagtgaaaa ggaagccaca ccagtggtgc atgaaacaga 2000

 accagaatca gggtctcaac ctcggccggc tgtattatct ggctatttca 2050

 aacagtttca gaagtcttta cctccacgat tccagcggca gcaggaacag 2100

 atgaaacagc agcagtggca gcagcagcaa cagcaaggtg tacttccaca 2150

 gactgttcct tcacaaccgt ccagtagtac tgtccctcct ccaccacaca 2200

 gacctcttta tcagcctatg cagcctcatc ctcagcattt ggcttctatg 2250

 ggttttgatc caaggtggct catgatgcag tcctacatgg atcctcgaat 2300

 gatgtcagga agacctgcta tggatattcc acccattcat cctggaatga 2350

 ttcctcctaa accattaatg agaagagacc agatggaagg gtcaccgaac 2400

 agttctgagt catttgagca tatagctcga tctgcaagag atcacgcaat 2450

 ttccctttct gagcctcgta tgctgtgggg gtcagatccc tatcctcatg 2500

 ctgagcctca acaagcaact actcccaaag caacagaaga gcctgaggat 2550

 gtaaggtctg aagctgcgtt ggaccaggaa cagattactg ctgcttattc 2600

 tgtagaacat aatcaattag aggctcaccc aaaggcagac tttatcagag 2650

 aatcaagtga ggcacaagta caaaagtttt taagcagatc tgtggaagat 2700

 gttagacctc accatactga tgcaaataat cagtctgctt gttttgaagc 2750

 acctgatcaa aagaccttat ccgctcctca agaggagcgg atttcagctg 2800

 tagaaagtca gccttcccgg aaaagaagtg tttcccatgg atctaaccat 2850

 acgcaaaaac cagacgagca gagaagtgaa ccatctgcag gcattcctaa 2900

 agtaaccagc agatgcattg attcaaaaga accaatagaa aggccagagg 2950

 agaaaccaaa aaaggaaggc tttatacgat cttctgaagg accaaaacct 3000

 gaaaaagtat ataaatctaa atcagaaact cgttggggcc cacgaccaag 3050

 ctctaacaga agggaagaag ttaatgatag acctgtgaga agatcaggtc 3100

 ccattaaaaa acctgtactt agagatatga aagaggaacg ggaacagagg 3150

 aaggagaaag aaggagaaaa ggccgaaaag gtcactgaaa aagtagttgt 3200

 aaagcctgaa aagacggaaa agaaggatct tcctcctccc ccaccaccac 3250

 ctcagccacc agcaccaatt cagccacagt cagttccacc accaattcaa 3300

 ccagaagcag agaaatttcc ttcaacagaa actgcaactt tggctcaaaa 3350

 accatctcag gatactgaga agcctctgga acctgtgagt actgttcagg 3400

 tagagcctgc agttaagact gtaaaccaac agactatggc agcaccagta 3450

 gtcaaagaag aaaaacaacc tgagaaagtc atcagcaaag accttgttat 3500

 agagaggcct cgaccagatt caagaccagc agttaaaaaa gaatcaactt 3550

 tgcctcccag gacctattgg aaagaagcta gagagagaga ttggtttcca 3600

 gatcaaggat acagaggtcg aggccgaggt gaatattact ccagaggtcg 3650

 aagctataga ggttcttatg gagggcgtgg caggggtggt aggggacaca 3700

 ctcgagatta tcctcagtat agagacaata agccaagagc agagcatata 3750

 ccctcagggc ctctcagaca gcgagaagaa agtgaaacac ggagtgagag 3800

 ctctgatttt gaagttgtcc ccaaaagaag acgacagcgg ggttcagaga 3850

 ctgacacaga cagtgaaatt catgaaagtg caagtgacaa ggacagttta 3900

 agtaaaggca aacttcccaa aagagaggaa cggcctgaaa acaaaaaacc 3950

 tgtaaagcct cattcttctt tcaagcctga taatcatgtt cgaatagata 4000

 atagactgct agaaaagcct tatgtaaggg atgacgataa agctaaacca 4050

 ggctttcttc ctaaaggaga gcctacaagg agaggcagag ggggaacatt 4100

 caggcgtggt ggaagggatc ctggaggccg tccatcacgc ccttccactt 4150

 tacgaagacc agcttatcgg gacaatcagt ggaacccaag gcagtcagaa 4200

 gttcctaaac cagaagatgg agagccgcca agaagacatg agcagtttat 4250

 tcctatagca gcagataaac gacctccaaa atttgagcga aaatttgacc 4300

 cagctagaga aaggcctcga aggcagcgtc ctactcgacc accaaggcaa 4350

 gacaagccac ctcgatttag acggctaaga gagagggagg ctgcttcaaa 4400

 atcaaatgag gtggtagcag tgcccacaaa tggcacagtt aataatgtgg 4450

 ctcaagaacc agttaatact cttggggata tttccgggaa taagacacca 4500

 gatttatcta atcagaactc ttcagatcag gcaaatgaag aatgggaaac 4550

 agcttctgaa agcagtgatt tcaatgagag gcgagagagg gatgaaaaaa 4600

 aaaatgctga cttgaatgca caaacagttg taaaggttgg agagaatgtt 4650

 ctacctccaa agagggaaat tgcaaagaga agtttttcta gtcagagacc 4700

 agtagatcgt cagaatcgac gtggcaacaa tggtccaccc aaatcaggaa 4750

 ggaatttctc aggtcctaga aatgaaagga gaagtggccc accatcaaaa 4800

 agtgggaaga gagggccatt tgatgaccag cctgcaggca caactggggt 4850

 tgacctcatc aatggcagct ctgcacacca tcaggaagga gtacctaatg 4900

 gtacaggaca aaagaactcc aaagattcta ctgggaaaaa aagagaagac 4950

 cccaaaccag gccctaaaaa accaaaagag aaagtggatg ctctatcaca 5000

 gtttgatctc aacaattatg caagtgttgt tataattgat gatcatcctg 5050

 aagtaacagt aattgaagat ccccagtcaa atttgaatga tgatggtttt 5100

 actgaagtgg tatccaaaaa acaacaaaaa cgtttacagg atgaagaacg 5150

 ccgaaagaag gaagaacaag tcatacaggt ctggaacaaa aagaatgcaa 5200

 atgaaaaagg aagaagccag acttctaagc ttcctccaag atttgccaaa 5250

 aaacaggcta cagggatcca gcaagcacag tcttcagcct cagttccacc 5300

 tctagcttcg gctccacttc caccttcaac ctcagcttca gttccagcct 5350

 caacctcagc tccacttccg gcaaccttaa ctccagttcc agcctcaacc 5400

 tcagctccgg ttccagcctc aactttagct ccagttctgg cctcaacctc 5450

 agctccagtt ccagcctcac ccttagctcc agtttcagcc tcagcctcag 5500

 tctcagcttc agttccagcc tctacttcag ctgcagctat aacctcttct 5550

 tcagctccag cctcagcccc agctccaacc cccatccttg cctcagtttc 5600

 aaccccagct tctgtcacca ttcttgcctc agcctcaatt cccattcttg 5650

 cttcagccct agcatcaact tcagctccaa cgccagcccc agcagcctct 5700

 tccccagctg ccccagtcat cacagcacca actatcccag cctcagcccc 5750

 aactgcctca gtcccacttg cccctgcctc agcttcagcc ccagccccag 5800

 cccctacccc agtctcagcc ccaaatcctg ccccacctgc cccagcccag 5850

 actcaggcac agacccacaa accagtccag aatccactac agactacatc 5900

 tcagtcttca aaacaaccac caccatcaat taggctgcct tcagctcaaa 5950

 cacctaatgg cacagattat gtagcctcag gaaaatccat ccagacccca 6000

 cagtcacatg gcactctgac agctgaatta tgggataaca aggtggcccc 6050

 accagctgtg ctgaatgata tctctaagaa attaggtccc attagtccac 6100

 cacagccacc ttcagtcagt gcatggaata agcccttaac atcgtttgga 6150

 tcagctcctt catcagaggg agcgaagaat ggtcaagaaa gtggactcga 6200

 aattggaact gacacaattc agtttggtgc tccagcctca aatggaaatg 6250

 aaaatgaagt tgttcctgtg ctttcggaaa aatctgctga caaaatacct 6300

 gaacctaaag aacagcggca gaagcagcca cgagcaggac ctatcaaagc 6350

 ccagaagctt ccagatttga gtccagtaga aaacaaagaa cacaaacctg 6400

 gtcccattgg aaaggaacgt tcattaaaaa atagaaaagt aaaagatgcc 6450

 caacaggtgg agccagaagg acaagagaaa ccaagcccag ctacagtcag 6500

 aagcacagat cctgtcacga caaaggagac taaagcagtc tcagaaatgt 6550

 ctactgaaat aggaacaatg atctcggtat catctgcaga atatggtact 6600

 aatgcaaagg agtctgtaac agactatact acaccctctt cttctttgcc 6650

 taacaccgtg gctactaata atacaaagat ggaggatact ttggttaata 6700

 atgtgcccct gcccaacacc cttcccctcc ctaagaggga gactatacaa 6750

 cagagctcca gcctaacttc agttcctccc actactttca gcctcacctt 6800

 caagatggag tctgcacgca aagcatggga gaattctcca aatgtaaggg 6850

 aaaaggggtc tccagtaact tccacagcac ctccaattgc aactggagtc 6900

 agcagtagtg ccagtggacc aagcactgct aattacaatt cgttctcaag 6950

 tgcatccatg ccccagattc ctgttgcttc agtcactcct acagcatcac 7000

 tatcaggagc tggtacatac actacctctt ctttgagcac aaaatctaca 7050

 accacatcgg accctccaaa tatttgtaaa gtgaaacctc agcagttaca 7100

 gacaagcagc ctgccttctg caagtcattt ttcacagtta agctgtatgc 7150

 cttcccttat tgcccagcag caacagaatc cgcaagttta tgtgtctcag 7200

 tctgcagcag ctcaaatccc agccttctat atggacacaa gtcatttatt 7250

 caatacccaa catgcacgat tggctccgcc atccttggct caacaacagg 7300

 gtttccaacc aggtctctct cagccaactt cagttcagca gattccaatc 7350

 cctatttatg caccactgca agggcagcat caagcccaac tgagtttggg 7400

 ggctggccct gctgtttccc aggctcagga attgttcagc tcctcacttc 7450

 aaccatatag atctcagcca gcttttatgc aaagcagttt atcccagcca 7500

 tctgtggtcc tttctggtac tgctattcac aactttccaa ctgtccaaca 7550

 ccaagaactt gccaaggcac aatccggtct tgcctttcag caaacatcaa 7600

 atactcagcc cattcctata ttgtatgaac atcaactggg gcaggcatca 7650

 ggactaggag gttcccagct gattgacaca catcttctcc aggccagagc 7700

 aaatcttacc caggcctcaa atctttattc tggacaagta caacagcctg 7750

 gtcagacaaa tttttataac actgcccagt caccaagtgc tctccagcag 7800

 gttacagtac ctttaccagc atcgcagctt tccttgccta attttggatc 7850

 tacagggcaa cctctaattg ctttgcctca gactcttcag cccccattac 7900

 agcataccac tccccaagca caggctcaga gtctgagtcg tcctgcacaa 7950

 gtaagccagc ctttcagagg attaattcct gctggaacac agcatagcat 8000

 gattgcaacc acaggaaaaa tgtctgaaat ggaactaaaa gcctttggaa 8050

 gtggcattga tataaaacca ggcacacctc caatcgctgg tagaagcacc 8100

 acaccaacat ctagtccttc cgggctactt ctacaagtcc gaacagccag 8150

 tccagcaaaa tgaacagcat tgtctaccag aagcagttcc agtcagcccc 8200

 tgccactgtg agaatgacac aaccatttcc tacacagttt gcaccccagg 8250

 caaagcagag agcagaggtt cttcagtcca cgcaacggtt cttctctgaa 8300

 cagcaacaga gcaaacagat aggaggaggc aaagcccaga aagtggacag 8350

 tgattcaagt aaacctcctg aaacactgac cgaccctcct ggggtctgtc 8400

 aggaaaaagt agaagaaaag ccaccccctg caccctccat agccaccaaa 8450

 cctgttagaa ctggaccaat caaacctcag gcgatcaaaa ccgaagaaac 8500

 aaaatcttaa aggctatggt ttattgcagg ggattgggag gggggcggga 8550

 aaacatggag aattaagtca gataatgctg gcagccaaag gggcaaaatg 8600

 gcctgtgaca ttatcctgtt cagagcttgg agatgtacaa gggacatagg 8650

 agcaatttac actgacacac agctgctgta ccagtgaaaa cgaggctttg 8700

 caagcttgta cctactatat aacatgtgct tggttgatgg ccatgcatct 8750

 tcagtcagaa tttatatata aatgtatgca cccatttttt tgagtgcata 8800

 taatttagac ctaaaaatcc ttatgattag atgaaacacc aaaaatataa 8850

 ggaaaataac acagcagagg aatagctcag cctgaacagt gtgatggtcc 8900

 cagctactac atcagatgcg gtttttttgc tcccttatgt tcttcggata 8950

 tggttatggc atttgtaggc ttggaggtaa agaactgaag ataactggtg 9000

 ctggatagag gagccttatt ttttattatg gcagcttgct atttttataa 9050

 catggtgatt gagttgaaca caatcaaagt acagtagtaa ctgatgtccc 9100

 cttcttcctg gatgaatgag cagataaata ttgatgtcag catccttgaa 9150

 ccatatcaaa gtgagcagtg tttggctact gcttctattt gaaatggtgc 9200

 tgtgttttgg ttgtggtctg aagctttgaa gcgctactta gcatctcctt 9250

 tcttccatgg agctctcacg attcaaacat gacagatttg gtaaaatgct 9300

 ggttaggttg agtcttcctt gcccccactc agtcatcttt gtatgaatcc 9350

 catgatttgg gggttttttt cttttttttt ttataccagt ttttagctgg 9400

 tgtttatgaa gaacagtgag tacctagaac tgtgccacta attaaaggaa 9450

 atcctaagaa ggtgcatttc tttacagagc tgtgtcatgc catcctttgg 9500

 gccctctgct ggaaaagtag aatcaagtct caaataatgc ctttttaatt 9550

 gtatcctcta gtattataga tataggacag tactgtatca tacctctgtg 9600

 aatgtaaaat atcttgtacc tgctttatga tacgtagtag tgaccgtgct 9650

 ttatcagagc tgtttttaat gatgttattc tagaatgttt tctttccaga 9700

 tgatgattca gaagctaatt ttaaaaaacg gtgccaggta ccacaacagt 9750

 aacagaactt tgcaattttc tggggttttg ttttttacct ttttcccccc 9800

 ttttttttaa atggagtgtg ctggatgtct ctataatttt attcagatga 9850

 ctgcagaacc tggaaaagct gttgctgcta ttgatgcata acatactgct 9900

 attggtcttt ttatataaat atatatatat atatacatat atatatataa 9950

 tttgaatttt tggaaacttt agctgtgctg tcaactttgg aaaaagtatc 10000

 ccggtttact gtgttgagtt ggcattgtac agaaattaac agccatattg 10050

 gtctagaaac gttaaactta atttttttcc atttgtacag gggtaacgca 10100

 ctgtattaaa tatgtaaggt cttatctaca tgggtttgat tacagaaact 10150

 aataaagtat tctctaaata atga 10174

<210> 4820
<211> 2000
<212> PRT
<213> Homo sapien

<400> 4820
 Met Ser Glu Lys Ser Gly Gln Ser Thr Lys Ala Lys Asp Gly Lys
   1               5                  10                  15

 Lys Tyr Ala Thr Leu Ser Leu Phe Asn Thr Tyr Lys Gly Lys Ser
                  20                  25                  30

 Leu Glu Thr Gln Lys Thr Thr Ala Arg His Gly Leu Gln Ser Leu
                  35                  40                  45

 Gly Lys Val Gly Ile Ser Arg Arg Met Pro Pro Pro Ala Asn Leu
                  50                  55                  60

 Pro Ser Leu Lys Ala Glu Asn Lys Gly Asn Asp Pro Asn Val Asn
                  65                  70                  75

 Ile Val Pro Lys Asp Gly Thr Gly Trp Ala Ser Lys Gln Glu Gln
                  80                  85                  90

 His Glu Glu Glu Lys Thr Pro Glu Val Pro Pro Ala Gln Pro Lys
                  95                 100                 105

 Pro Gly Val Ala Ala Pro Pro Glu Val Ala Pro Ala Pro Lys Ser
                 110                 115                 120

 Trp Ala Ser Asn Lys Gln Gly Gly Gln Gly Asp Gly Ile Gln Val
                 125                 130                 135

 Asn Ser Gln Phe Gln Gln Glu Phe Pro Ser Leu Gln Ala Ala Gly
                 140                 145                 150

 Asp Gln Glu Lys Lys Glu Lys Glu Thr Asn Asp Asp Asn Tyr Gly
                 155                 160                 165

 Pro Gly Pro Ser Leu Arg Pro Pro Asn Val Ala Cys Trp Arg Asp
                 170                 175                 180

 Gly Gly Lys Ala Ala Gly Ser Pro Ser Ser Ser Asp Gln Asp Glu
                 185                 190                 195

 Lys Leu Pro Gly Gln Asp Glu Ser Thr Ala Gly Thr Ser Glu Gln
                 200                 205                 210

 Asn Asp Ile Leu Lys Val Val Glu Lys Arg Ile Ala Cys Gly Pro
                 215                 220                 225

 Pro Gln Ala Lys Leu Asn Gly Gln Gln Ala Ala Leu Ala Ser Gln
                 230                 235                 240

 Tyr Arg Ala Met Met Pro Pro Tyr Met Phe Gln Gln Tyr Pro Arg
                 245                 250                 255

 Met Thr Tyr Pro Pro Leu His Gly Pro Met Arg Phe Pro Pro Ser
                 260                 265                 270

 Leu Ser Glu Thr Asn Lys Gly Leu Arg Gly Arg Gly Pro Pro Pro
                 275                 280                 285

 Ser Trp Ala Ser Glu Pro Glu Arg Pro Ser Ile Leu Ser Ala Ser
                 290                 295                 300

 Glu Leu Lys Glu Leu Asp Lys Phe Asp Asn Leu Asp Ala Glu Ala
                 305                 310                 315

 Asp Glu Gly Trp Ala Gly Ala Gln Met Glu Val Asp Tyr Thr Glu
                 320                 325                 330

 Gln Leu Asn Phe Ser Asp Asp Asp Glu Gln Gly Ser Asn Ser Pro
                 335                 340                 345

 Lys Glu Asn Asn Ser Glu Asp Gln Gly Ser Lys Ala Ser Glu Asn
                 350                 355                 360

 Asn Glu Asn Lys Lys Glu Thr Asp Glu Val Ser Asn Thr Lys Ser
                 365                 370                 375

 Ser Ser Gln Ile Pro Ala Gln Pro Ser Val Ala Lys Val Pro Tyr
                 380                 385                 390

 Gly Lys Gly Pro Ser Phe Asn Gln Glu Arg Gly Thr Ser Ser His
                 395                 400                 405

 Leu Pro Pro Pro Pro Lys Leu Leu Ala Gln Gln His Pro Pro Pro
                 410                 415                 420

 Asp Arg Gln Ala Val Pro Gly Arg Pro Gly Pro Phe Pro Ser Lys
                 425                 430                 435

 Gln Gln Val Ala Asp Glu Asp Glu Ile Trp Lys Gln Arg Arg Arg
                 440                 445                 450

 Gln Gln Ser Glu Ile Ser Ala Ala Val Glu Arg Ala Arg Lys Arg
                 455                 460                 465

 Arg Glu Glu Glu Glu Arg Arg Met Glu Glu Gln Arg Lys Ala Ala
                 470                 475                 480

 Cys Ala Glu Lys Leu Lys Arg Leu Asp Glu Lys Leu Gly Ile Leu
                 485                 490                 495

 Glu Lys Gln Pro Ser Pro Glu Glu Ile Arg Glu Arg Glu Arg Glu
                 500                 505                 510

 Lys Glu Arg Glu Arg Glu Lys Glu Leu Glu Lys Glu Gln Glu Gln
                 515                 520                 525

 Glu Arg Glu Lys Glu Arg Glu Lys Asp Arg Glu Arg Gln Gln Glu
                 530                 535                 540

 Lys Glu Lys Glu Leu Glu Lys Glu Gln Glu Lys Gln Arg Glu Met
                 545                 550                 555

 Glu Lys Glu Arg Lys Gln Glu Lys Glu Lys Glu Leu Glu Arg Gln
                 560                 565                 570

 Lys Glu Lys Glu Lys Glu Leu Gln Lys Met Lys Glu Gln Glu Lys
                 575                 580                 585

 Glu Cys Glu Leu Glu Lys Glu Arg Glu Lys Leu Glu Glu Lys Ile
                 590                 595                 600

 Glu Pro Arg Glu Pro Asn Leu Glu Pro Met Val Glu Lys Gln Glu
                 605                 610                 615

 Ser Glu Asn Ser Cys Asn Lys Glu Glu Glu Pro Val Phe Thr Arg
                 620                 625                 630

 Gln Asp Ser Asn Arg Ser Glu Lys Glu Ala Thr Pro Val Val His
                 635                 640                 645

 Glu Thr Glu Pro Glu Ser Gly Ser Gln Pro Arg Pro Ala Val Leu
                 650                 655                 660

 Ser Gly Tyr Phe Lys Gln Phe Gln Lys Ser Leu Pro Pro Arg Phe
                 665                 670                 675

 Gln Arg Gln Gln Glu Gln Met Lys Gln Gln Gln Trp Gln Gln Gln
                 680                 685                 690

 Gln Gln Gln Gly Val Leu Pro Gln Thr Val Pro Ser Gln Pro Ser
                 695                 700                 705

 Ser Ser Thr Val Pro Pro Pro Pro His Arg Pro Leu Tyr Gln Pro
                 710                 715                 720

 Met Gln Pro His Pro Gln His Leu Ala Ser Met Gly Phe Asp Pro
                 725                 730                 735

 Arg Trp Leu Met Met Gln Ser Tyr Met Asp Pro Arg Met Met Ser
                 740                 745                 750

 Gly Arg Pro Ala Met Asp Ile Pro Pro Ile His Pro Gly Met Ile
                 755                 760                 765

 Pro Pro Lys Pro Leu Met Arg Arg Asp Gln Met Glu Gly Ser Pro
                 770                 775                 780

 Asn Ser Ser Glu Ser Phe Glu His Ile Ala Arg Ser Ala Arg Asp
                 785                 790                 795

 His Ala Ile Ser Leu Ser Glu Pro Arg Met Leu Trp Gly Ser Asp
                 800                 805                 810

 Pro Tyr Pro His Ala Glu Pro Gln Gln Ala Thr Thr Pro Lys Ala
                 815                 820                 825

 Thr Glu Glu Pro Glu Asp Val Arg Ser Glu Ala Ala Leu Asp Gln
                 830                 835                 840

 Glu Gln Ile Thr Ala Ala Tyr Ser Val Glu His Asn Gln Leu Glu
                 845                 850                 855

 Ala His Pro Lys Ala Asp Phe Ile Arg Glu Ser Ser Glu Ala Gln
                 860                 865                 870

 Val Gln Lys Phe Leu Ser Arg Ser Val Glu Asp Val Arg Pro His
                 875                 880                 885

 His Thr Asp Ala Asn Asn Gln Ser Ala Cys Phe Glu Ala Pro Asp
                 890                 895                 900

 Gln Lys Thr Leu Ser Ala Pro Gln Glu Glu Arg Ile Ser Ala Val
                 905                 910                 915

 Glu Ser Gln Pro Ser Arg Lys Arg Ser Val Ser His Gly Ser Asn
                 920                 925                 930

 His Thr Gln Lys Pro Asp Glu Gln Arg Ser Glu Pro Ser Ala Gly
                 935                 940                 945

 Ile Pro Lys Val Thr Ser Arg Cys Ile Asp Ser Lys Glu Pro Ile
                 950                 955                 960

 Glu Arg Pro Glu Glu Lys Pro Lys Lys Glu Gly Phe Ile Arg Ser
                 965                 970                 975

 Ser Glu Gly Pro Lys Pro Glu Lys Val Tyr Lys Ser Lys Ser Glu
                 980                 985                 990

 Thr Arg Trp Gly Pro Arg Pro Ser Ser Asn Arg Arg Glu Glu Val
                 995                1000                1005

 Asn Asp Arg Pro Val Arg Arg Ser Gly Pro Ile Lys Lys Pro Val
                1010                1015                1020

 Leu Arg Asp Met Lys Glu Glu Arg Glu Gln Arg Lys Glu Lys Glu
                1025                1030                1035

 Gly Glu Lys Ala Glu Lys Val Thr Glu Lys Val Val Val Lys Pro
                1040                1045                1050

 Glu Lys Thr Glu Lys Lys Asp Leu Pro Pro Pro Pro Pro Pro Pro
                1055                1060                1065

 Gln Pro Pro Ala Pro Ile Gln Pro Gln Ser Val Pro Pro Pro Ile
                1070                1075                1080

 Gln Pro Glu Ala Glu Lys Phe Pro Ser Thr Glu Thr Ala Thr Leu
                1085                1090                1095

 Ala Gln Lys Pro Ser Gln Asp Thr Glu Lys Pro Leu Glu Pro Val
                1100                1105                1110

 Ser Thr Val Gln Val Glu Pro Ala Val Lys Thr Val Asn Gln Gln
                1115                1120                1125

 Thr Met Ala Ala Pro Val Val Lys Glu Glu Lys Gln Pro Glu Lys
                1130                1135                1140

 Val Ile Ser Lys Asp Leu Val Ile Glu Arg Pro Arg Pro Asp Ser
                1145                1150                1155

 Arg Pro Ala Val Lys Lys Glu Ser Thr Leu Pro Pro Arg Thr Tyr
                1160                1165                1170

 Trp Lys Glu Ala Arg Glu Arg Asp Trp Phe Pro Asp Gln Gly Tyr
                1175                1180                1185

 Arg Gly Arg Gly Arg Gly Glu Tyr Tyr Ser Arg Gly Arg Ser Tyr
                1190                1195                1200

 Arg Gly Ser Tyr Gly Gly Arg Gly Arg Gly Gly Arg Gly His Thr
                1205                1210                1215

 Arg Asp Tyr Pro Gln Tyr Arg Asp Asn Lys Pro Arg Ala Glu His
                1220                1225                1230

 Ile Pro Ser Gly Pro Leu Arg Gln Arg Glu Glu Ser Glu Thr Arg
                1235                1240                1245

 Ser Glu Ser Ser Asp Phe Glu Val Val Pro Lys Arg Arg Arg Gln
                1250                1255                1260

 Arg Gly Ser Glu Thr Asp Thr Asp Ser Glu Ile His Glu Ser Ala
                1265                1270                1275

 Ser Asp Lys Asp Ser Leu Ser Lys Gly Lys Leu Pro Lys Arg Glu
                1280                1285                1290

 Glu Arg Pro Glu Asn Lys Lys Pro Val Lys Pro His Ser Ser Phe
                1295                1300                1305

 Lys Pro Asp Asn His Val Arg Ile Asp Asn Arg Leu Leu Glu Lys
                1310                1315                1320

 Pro Tyr Val Arg Asp Asp Asp Lys Ala Lys Pro Gly Phe Leu Pro
                1325                1330                1335

 Lys Gly Glu Pro Thr Arg Arg Gly Arg Gly Gly Thr Phe Arg Arg
                1340                1345                1350

 Gly Gly Arg Asp Pro Gly Gly Arg Pro Ser Arg Pro Ser Thr Leu
                1355                1360                1365

 Arg Arg Pro Ala Tyr Arg Asp Asn Gln Trp Asn Pro Arg Gln Ser
                1370                1375                1380

 Glu Val Pro Lys Pro Glu Asp Gly Glu Pro Pro Arg Arg His Glu
                1385                1390                1395

 Gln Phe Ile Pro Ile Ala Ala Asp Lys Arg Pro Pro Lys Phe Glu
                1400                1405                1410

 Arg Lys Phe Asp Pro Ala Arg Glu Arg Pro Arg Arg Gln Arg Pro
                1415                1420                1425

 Thr Arg Pro Pro Arg Gln Asp Lys Pro Pro Arg Phe Arg Arg Leu
                1430                1435                1440

 Arg Glu Arg Glu Ala Ala Ser Lys Ser Asn Glu Val Val Ala Val
                1445                1450                1455

 Pro Thr Asn Gly Thr Val Asn Asn Val Ala Gln Glu Pro Val Asn
                1460                1465                1470

 Thr Leu Gly Asp Ile Ser Gly Asn Lys Thr Pro Asp Leu Ser Asn
                1475                1480                1485

 Gln Asn Ser Ser Asp Gln Ala Asn Glu Glu Trp Glu Thr Ala Ser
                1490                1495                1500

 Glu Ser Ser Asp Phe Asn Glu Arg Arg Glu Arg Asp Glu Lys Lys
                1505                1510                1515

 Asn Ala Asp Leu Asn Ala Gln Thr Val Val Lys Val Gly Glu Asn
                1520                1525                1530

 Val Leu Pro Pro Lys Arg Glu Ile Ala Lys Arg Ser Phe Ser Ser
                1535                1540                1545

 Gln Arg Pro Val Asp Arg Gln Asn Arg Arg Gly Asn Asn Gly Pro
                1550                1555                1560

 Pro Lys Ser Gly Arg Asn Phe Ser Gly Pro Arg Asn Glu Arg Arg
                1565                1570                1575

 Ser Gly Pro Pro Ser Lys Ser Gly Lys Arg Gly Pro Phe Asp Asp
                1580                1585                1590

 Gln Pro Ala Gly Thr Thr Gly Val Asp Leu Ile Asn Gly Ser Ser
                1595                1600                1605

 Ala His His Gln Glu Gly Val Pro Asn Gly Thr Gly Gln Lys Asn
                1610                1615                1620

 Ser Lys Asp Ser Thr Gly Lys Lys Arg Glu Asp Pro Lys Pro Gly
                1625                1630                1635

 Pro Lys Lys Pro Lys Glu Lys Val Asp Ala Leu Ser Gln Phe Asp
                1640                1645                1650

 Leu Asn Asn Tyr Ala Ser Val Val Ile Ile Asp Asp His Pro Glu
                1655                1660                1665

 Val Thr Val Ile Glu Asp Pro Gln Ser Asn Leu Asn Asp Asp Gly
                1670                1675                1680

 Phe Thr Glu Val Val Ser Lys Lys Gln Gln Lys Arg Leu Gln Asp
                1685                1690                1695

 Glu Glu Arg Arg Lys Lys Glu Glu Gln Val Ile Gln Val Trp Asn
                1700                1705                1710

 Lys Lys Asn Ala Asn Glu Lys Gly Arg Ser Gln Thr Ser Lys Leu
                1715                1720                1725

 Pro Pro Arg Phe Ala Lys Lys Gln Ala Thr Gly Ile Gln Gln Ala
                1730                1735                1740

 Gln Ser Ser Ala Ser Val Pro Pro Leu Ala Ser Ala Pro Leu Pro
                1745                1750                1755

 Pro Ser Thr Ser Ala Ser Val Pro Ala Ser Thr Ser Ala Pro Leu
                1760                1765                1770

 Pro Ala Thr Leu Thr Pro Val Pro Ala Ser Thr Ser Ala Pro Val
                1775                1780                1785

 Pro Ala Ser Thr Leu Ala Pro Val Leu Ala Ser Thr Ser Ala Pro
                1790                1795                1800

 Val Pro Ala Ser Pro Leu Ala Pro Val Ser Ala Ser Ala Ser Val
                1805                1810                1815

 Ser Ala Ser Val Pro Ala Ser Thr Ser Ala Ala Ala Ile Thr Ser
                1820                1825                1830

 Ser Ser Ala Pro Ala Ser Ala Pro Ala Pro Thr Pro Ile Leu Ala
                1835                1840                1845

 Ser Val Ser Thr Pro Ala Ser Val Thr Ile Leu Ala Ser Ala Ser
                1850                1855                1860

 Ile Pro Ile Leu Ala Ser Ala Leu Ala Ser Thr Ser Ala Pro Thr
                1865                1870                1875

 Pro Ala Pro Ala Ala Ser Ser Pro Ala Ala Pro Val Ile Thr Ala
                1880                1885                1890

 Pro Thr Ile Pro Ala Ser Ala Pro Thr Ala Ser Val Pro Leu Ala
                1895                1900                1905

 Pro Ala Ser Ala Ser Ala Pro Ala Pro Ala Pro Thr Pro Val Ser
                1910                1915                1920

 Ala Pro Asn Pro Ala Pro Pro Ala Pro Ala Gln Thr Gln Ala Gln
                1925                1930                1935

 Thr His Lys Pro Val Gln Asn Pro Leu Gln Thr Thr Ser Gln Ser
                1940                1945                1950

 Ser Lys Gln Pro Pro Pro Ser Ile Arg Leu Pro Ser Ala Gln Thr
                1955                1960                1965

 Pro Asn Gly Thr Asp Tyr Val Ala Ser Gly Lys Ser Ile Gln Thr
                1970                1975                1980

 Pro Gln Ser His Gly Thr Leu Thr Ala Glu Leu Trp Asp Asn Lys
                1985                1990                1995

 Val Ala Pro Pro Ala
                2000

<210> 4821
<211> 2179
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 520-812
<223> Unknown base

<400> 4821
 ctgtttcctt tgcaaactga cataaaaatg aagaagcaaa atgtgtcttt 50

 agttatatcc aagttccaaa ttcaagttaa ttactgctgc tcctcactct 100

 tctacctttt ccttcaaatt taaagatggg ctttgcagag attaaagctt 150

 cagaaaaaaa tatgggaaaa tatgttaaaa tgttgacctg aaaatgaagt 200

 ggatgactat aaaactcttg agagaattag actttttgta gcagtttatt 250

 acatgataat accttaaagg agatcacatt cagtgacctg cgttgacagg 300

 taatatttaa aattaagtat taatgctgat taattcaggc agatgggtgg 350

 tagcctaaag tatagacatt tttccaatat taattttgat attaaataaa 400

 tgacatcggc tcttgttgga tattgtaaaa tttcctttac ttcaactgta 450

 aaataatttc aacagtgaaa ggtataaagt aagatgaaaa tttccatcat 500

 gatcttacct agagataacn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 650

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 700

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnttctttgt taattttata tgtttcggtt atgtaaatat 850

 ataactgaaa gggtaaatat atataaatac atatttactg cacatttata 900

 ttgatatata tttctctgct tgtatctatc tatatacaca ctttataaat 950

 aaatgagtca agatttttaa aacaaaatac caaatttttc agtatcattt 1000

 gaaatttttc aaaattactt ttttaaaatt tctgcatatt cattcagtga 1050

 agttgaatga tccagtgggc actctgtatt ccttcataaa ctgtgtggtg 1100

 aatgtggcgt gtcgtgtata tggtatgtat atggcacgtg tttatgtgtt 1150

 ttctggggtt aatttcctta aaataaaaag gcaactgtca agactaaagc 1200

 tataataatt tttatgaatc ttagaaaatg ttgaattttt agtgattcca 1250

 gaaattgatc tctatcgatg aaactgcttt ctcaaatacg tcagcaatgg 1300

 gatccaggct ttgcttacaa tgtgaaggaa gttcttagtc tcattgcaca 1350

 aagaaggaag gagggctaaa gataaaaaga actcatagtc ttttccatag 1400

 ttttgggtca tgttcactgt aaaaaaaaat cacaagatgc catttttaca 1450

 cagccttttt aatctacaca tacggcaagc taataattcc aaaaaaataa 1500

 tttctttcct ttgtagccat ttaaaactaa cagctagaaa tatttcttct 1550

 tccaattatt aaaaataagc tgtttctgag tcggtgctga ctacatttac 1600

 tgattgaagc agccaactcc aaatatacca tcttttagta ttgacactta 1650

 aaataaaact tctccccaga aaaagagttc tataaatgat ggctgtagaa 1700

 ataggcactg tccaggcagt tgttttgtgg aagtagtgtt gttattttct 1750

 ggtgttttcc aagtcatctc agatggtgcg tgaaaatgag atgccaaaga 1800

 aggcttaaaa aagataccct gcaccagctt cagaatgtaa gcaaatcttt 1850

 cattccagcg cttaaaagtt ttgagaaagc taatctaaag ttaaatgttt 1900

 actagcatct ctccgattat attttagaaa ctactgcaca aaaataaaac 1950

 aaatttctta ttttctctgg gttgaaaagt gcacataaaa tggaaaatgc 2000

 tttttatacc actatttcca gcagggattt tattttcatt tgtcatttgc 2050

 cagcctgggg tatgttggga gaaggaacaa ttgatttttg aaaaggtgca 2100

 tttgtgtgaa aaccaaaaat tgtgttcaac aaatactact actaacccat 2150

 atgtggatat atgtgtttta tacatgagt 2179

<210> 4822
<211> 120
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 13-110
<223> unknown amino acid

<220>
<221> Unsure
<222> 520-812
<223> Unknown amino acid

<400> 4822
 Met Lys Ile Ser Ile Met Ile Leu Pro Arg Asp Asn Xaa Xaa Xaa
   1               5                  10                  15

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Ser Leu Leu Ile Leu Tyr Val Ser Val Met
                 110                 115                 120

<210> 4823
<211> 2192
<212> DNA
<213> Homo sapien

<400> 4823
 ggggcggaga gaggcgagca ccgggaaggg gagcgtgggg ccgctggaat 50

 gggtgaattt aaggtccatc gagtacgttt ctttaattat gttccatcag 100

 gaatccgctg tgtggcttac aataaccagt caaacagatt ggctgtttca 150

 cgaacagatg gcactgtgga aatttataac ttgtcagcaa actactttca 200

 ggagaaattt ttcccaggtc atgagtctcg ggctacagaa gctttgtgct 250

 gggcagaagg acagcgactc tttagtgctg ggctcaatgg cgagattatg 300

 gagtatgatt tacaggcgtt aaacatcaag tatgctatgg atgcctttgg 350

 aggacctatt tggagcatgg ctgccagccc cagtggctct caacttttgg 400

 ttggttgtga agatggatct gtgaaactat ttcaaattac cccagacaaa 450

 atccagtttg aaagaaattt tgatcggcag aaaagtcgca tcctgagtct 500

 cagctggcat ccctctggta cccacattgc agctggttcc atagactaca 550

 ttagtgtgtt tgatgtcaaa tcaggcagcg ctgttcataa gatgattgtg 600

 gacaggcagt atatgggcgt gtctaagcgg aagtgcatcg tgtggggtgt 650

 cgccttcttg tccgatggca ctatcataag tgtggactct gctgggaagg 700

 tgcagttctg ggactcagcc actgggacgc ttgtgaagag ccatctcatc 750

 gctaatgctg acgtgcagtc cattgctgta gctgaccaag aagacagttt 800

 cgtggtgggc acagccgagg gaacagtctt ccattttcag ctggtccctg 850

 tgacatctaa cagcagtgag aagcagtggg tgcggacaaa accgttccag 900

 catcacactc atgacatgcg cactgtggcc cacagcccaa cagcgctgat 950

 atctggaggc actgacaccc acttagtctt tcgtcctctc atggagaagg 1000

 tggaagtaaa gaattacgat gccgctctcc gaaaaatcac ctttccccac 1050

 cgatgtctca tctcctgttc taaaaagagg cagcttctcc tcttccagtt 1100

 tgctcatcac ttagaacttt ggcgactggg atccacagtt gcaacaggca 1150

 agaatgggga tactcttcca ctctctaaaa atgcagatca tttactgcac 1200

 ctaaagacaa agggtcctga gaacattatc tgtagctgta tctccccatg 1250

 tggaagttgg atagcctatt ctacagtttc tcggtttttt ctctatcggc 1300

 tgaattatga acatgacaac ataagcctca aaagggtttc caaaatgcca 1350

 gcattccttc gctctgccct tcagattttg ttttctgaag attcaacaaa 1400

 gctctttgta gcatcaaatc aaggagctct gcatattgtt cagctgtcag 1450

 gaggaagctt caagcacctg catgctttcc agcctcagtc aggaacagtg 1500

 gaggccatgt gtcttttggc agtcagtcca gatgggaatt ggctagctgc 1550

 atcaggtacc agtgctggag tccatgtcta caacgtaaaa cagctaaagc 1600

 ttcactgcac ggtgcctgct tacaatttcc cagtgactgc tatggctatt 1650

 gcccccaata ccaacaacct tgtcatcgct cattcggacc agcaggtatt 1700

 tgagtacagc atcccagaca aacagtatac agattggagc cggactgtcc 1750

 agaagcaggg ctttcaccac ctttggctcc aaagggatac tcctatcaca 1800

 cacatcagtt ttcatcccaa gagaccgatg cacatccttc tccatgatgc 1850

 ctacatgttc tgcatcattg acaagtcatt gccccttcca aatgacaaaa 1900

 ccttactcta caatccattt cctcccacga atgaatcaga tgtcatccgg 1950

 aggcgcacag ctcatgcttt taaaatttct aagatatata agcctctact 2000

 cttcatggat cttttggatg aaagaacact cgtggcagta gaacggcctc 2050

 tggatgacat cattgctcag ctcccaccac ccattaaaaa gaagaaattt 2100

 ggaacctaaa acagggcact gtctgtgtcc ttccttgaac tgtctaccct 2150

 gttgcttttc acaaatcatg gtaataaaac aagttattct tg 2192

<210> 4824
<211> 686
<212> PRT
<213> Homo sapien

<400> 4824
 Met Gly Glu Phe Lys Val His Arg Val Arg Phe Phe Asn Tyr Val
   1               5                  10                  15

 Pro Ser Gly Ile Arg Cys Val Ala Tyr Asn Asn Gln Ser Asn Arg
                  20                  25                  30

 Leu Ala Val Ser Arg Thr Asp Gly Thr Val Glu Ile Tyr Asn Leu
                  35                  40                  45

 Ser Ala Asn Tyr Phe Gln Glu Lys Phe Phe Pro Gly His Glu Ser
                  50                  55                  60

 Arg Ala Thr Glu Ala Leu Cys Trp Ala Glu Gly Gln Arg Leu Phe
                  65                  70                  75

 Ser Ala Gly Leu Asn Gly Glu Ile Met Glu Tyr Asp Leu Gln Ala
                  80                  85                  90

 Leu Asn Ile Lys Tyr Ala Met Asp Ala Phe Gly Gly Pro Ile Trp
                  95                 100                 105

 Ser Met Ala Ala Ser Pro Ser Gly Ser Gln Leu Leu Val Gly Cys
                 110                 115                 120

 Glu Asp Gly Ser Val Lys Leu Phe Gln Ile Thr Pro Asp Lys Ile
                 125                 130                 135

 Gln Phe Glu Arg Asn Phe Asp Arg Gln Lys Ser Arg Ile Leu Ser
                 140                 145                 150

 Leu Ser Trp His Pro Ser Gly Thr His Ile Ala Ala Gly Ser Ile
                 155                 160                 165

 Asp Tyr Ile Ser Val Phe Asp Val Lys Ser Gly Ser Ala Val His
                 170                 175                 180

 Lys Met Ile Val Asp Arg Gln Tyr Met Gly Val Ser Lys Arg Lys
                 185                 190                 195

 Cys Ile Val Trp Gly Val Ala Phe Leu Ser Asp Gly Thr Ile Ile
                 200                 205                 210

 Ser Val Asp Ser Ala Gly Lys Val Gln Phe Trp Asp Ser Ala Thr
                 215                 220                 225

 Gly Thr Leu Val Lys Ser His Leu Ile Ala Asn Ala Asp Val Gln
                 230                 235                 240

 Ser Ile Ala Val Ala Asp Gln Glu Asp Ser Phe Val Val Gly Thr
                 245                 250                 255

 Ala Glu Gly Thr Val Phe His Phe Gln Leu Val Pro Val Thr Ser
                 260                 265                 270

 Asn Ser Ser Glu Lys Gln Trp Val Arg Thr Lys Pro Phe Gln His
                 275                 280                 285

 His Thr His Asp Met Arg Thr Val Ala His Ser Pro Thr Ala Leu
                 290                 295                 300

 Ile Ser Gly Gly Thr Asp Thr His Leu Val Phe Arg Pro Leu Met
                 305                 310                 315

 Glu Lys Val Glu Val Lys Asn Tyr Asp Ala Ala Leu Arg Lys Ile
                 320                 325                 330

 Thr Phe Pro His Arg Cys Leu Ile Ser Cys Ser Lys Lys Arg Gln
                 335                 340                 345

 Leu Leu Leu Phe Gln Phe Ala His His Leu Glu Leu Trp Arg Leu
                 350                 355                 360

 Gly Ser Thr Val Ala Thr Gly Lys Asn Gly Asp Thr Leu Pro Leu
                 365                 370                 375

 Ser Lys Asn Ala Asp His Leu Leu His Leu Lys Thr Lys Gly Pro
                 380                 385                 390

 Glu Asn Ile Ile Cys Ser Cys Ile Ser Pro Cys Gly Ser Trp Ile
                 395                 400                 405

 Ala Tyr Ser Thr Val Ser Arg Phe Phe Leu Tyr Arg Leu Asn Tyr
                 410                 415                 420

 Glu His Asp Asn Ile Ser Leu Lys Arg Val Ser Lys Met Pro Ala
                 425                 430                 435

 Phe Leu Arg Ser Ala Leu Gln Ile Leu Phe Ser Glu Asp Ser Thr
                 440                 445                 450

 Lys Leu Phe Val Ala Ser Asn Gln Gly Ala Leu His Ile Val Gln
                 455                 460                 465

 Leu Ser Gly Gly Ser Phe Lys His Leu His Ala Phe Gln Pro Gln
                 470                 475                 480

 Ser Gly Thr Val Glu Ala Met Cys Leu Leu Ala Val Ser Pro Asp
                 485                 490                 495

 Gly Asn Trp Leu Ala Ala Ser Gly Thr Ser Ala Gly Val His Val
                 500                 505                 510

 Tyr Asn Val Lys Gln Leu Lys Leu His Cys Thr Val Pro Ala Tyr
                 515                 520                 525

 Asn Phe Pro Val Thr Ala Met Ala Ile Ala Pro Asn Thr Asn Asn
                 530                 535                 540

 Leu Val Ile Ala His Ser Asp Gln Gln Val Phe Glu Tyr Ser Ile
                 545                 550                 555

 Pro Asp Lys Gln Tyr Thr Asp Trp Ser Arg Thr Val Gln Lys Gln
                 560                 565                 570

 Gly Phe His His Leu Trp Leu Gln Arg Asp Thr Pro Ile Thr His
                 575                 580                 585

 Ile Ser Phe His Pro Lys Arg Pro Met His Ile Leu Leu His Asp
                 590                 595                 600

 Ala Tyr Met Phe Cys Ile Ile Asp Lys Ser Leu Pro Leu Pro Asn
                 605                 610                 615

 Asp Lys Thr Leu Leu Tyr Asn Pro Phe Pro Pro Thr Asn Glu Ser
                 620                 625                 630

 Asp Val Ile Arg Arg Arg Thr Ala His Ala Phe Lys Ile Ser Lys
                 635                 640                 645

 Ile Tyr Lys Pro Leu Leu Phe Met Asp Leu Leu Asp Glu Arg Thr
                 650                 655                 660

 Leu Val Ala Val Glu Arg Pro Leu Asp Asp Ile Ile Ala Gln Leu
                 665                 670                 675

 Pro Pro Pro Ile Lys Lys Lys Lys Phe Gly Thr
                 680                 685

<210> 4825
<211> 1920
<212> DNA
<213> Homo sapien

<400> 4825
 gaaaggacag caacagtcag gtggtttacc ttccagaggc tggcaatgct 50

 gtttcactgg aggacacggc taagaaggaa gtccaccagc ctgccaagat 100

 gaattgcctt gaaggagagg gagagggatc ctggcccagc tgactttgaa 150

 tctgagggag ggccaagctg ccactgccct ggatgttgga acacctggtc 200

 ttgctgcttc ctcccaccac ctcaaaaaca cagaccttgg actacctgtc 250

 gcccatccct ttctggccta catttcccag caccagctct ccagcacagc 300

 actttggacc tcggctgccc tcaccagacc caactctctt ctgcagcctg 350

 ctgacctcgt ggccccctag gttcagtcat ctgacccagc tccaccctcg 400

 gcaccaacga atcttgcagc agcagcagca tagtcaaaca ccaagagagc 450

 cccacttcct gctcaccaca ctccttagga agtgccagtg gtgggtaagt 500

 ctaaagggtt gttcctcctg gcttaaagtc ccccagccaa gaagccttgg 550

 tctcagcagc cagaccccta tgctaacctc atgaccagaa aagagaagga 600

 ctgggtgata aaagtgcaga tggtgcagct gcagagtgca aaaccccgcc 650

 tggatgacta ctattaccag gaatattacc agaagctaga gaagaagcag 700

 gcagacgaag agctacttgg acgaagaaac cgggttgagt ccctcaagct 750

 ggtaacgcct tacattccga aggcagaggc ttatgagtcc gtggtccgaa 800

 tcgagggttc cctgggccag gtagctgtgt cgacatgctt cagccctcgc 850

 cgagctattg atgcggtacc ccatggaact caagagcagg atatagaagc 900

 tgcaagcagt cagaggcttc gggtattata ccggattgag aagatgttcc 950

 ttcagttact agaaatagag gaaggctgga agtataggcc tccaccgccc 1000

 tgcttttctg agcagcaaag caaccaggtt gagaagctct tccagacctt 1050

 aaagacccag gagcagaaca acctggaaga ggcagcagat ggcttcctgc 1100

 aggtgctctc tgtgaggaag gggaaggccc tggtggcccg gctgctcccc 1150

 ttcctgcccc aggatcaggc tgttaccatt cttttggcta tcacccacca 1200

 tctgcccctc ctggtccgga gggatgtggc tgatcaggcc ctacaaatgt 1250

 tattcaaacc tctgggcaaa tgtattagtc acttgaccct ccacgaactc 1300

 ctccaaggac ttcagggatt aacgctgttg ccacctggct cctcagagcg 1350

 gccagtcacc gtggtgcttc agaatcagtt tggaatatct ttgctctatg 1400

 ccctgctgag ccatggggag caactggtat cgctgcattc ttccctagag 1450

 gaacccaaca gtgaccatac agcttggaca gacatggtgg ttctgattgc 1500

 ctgggagata gcccaaatgc ctacagcctc tctggcagaa cccctagctt 1550

 tccccagcaa cctacttccc ctgttctgtc accacgtgga caaacaattg 1600

 gttcagcagc tggaggccag gatggagttt gcctggattt actgatctgt 1650

 ttgttctgga atacgtgtat gtgggaagtt gaatcatcag acactagcta 1700

 catagactat gtttacaggg atccagagag tctgaagaca tttcttatgc 1750

 ctttatatat tggagaaccc ttccccattt tcatatcctt tcttcaaaaa 1800

 tctaaatgat gtgcctaaaa ataagacatg gcataataag gtataattaa 1850

 agagataata gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaaaaaa 1920

<210> 4826
<211> 354
<212> PRT
<213> Homo sapien

<400> 4826
 Met Thr Arg Lys Glu Lys Asp Trp Val Ile Lys Val Gln Met Val
   1               5                  10                  15

 Gln Leu Gln Ser Ala Lys Pro Arg Leu Asp Asp Tyr Tyr Tyr Gln
                  20                  25                  30

 Glu Tyr Tyr Gln Lys Leu Glu Lys Lys Gln Ala Asp Glu Glu Leu
                  35                  40                  45

 Leu Gly Arg Arg Asn Arg Val Glu Ser Leu Lys Leu Val Thr Pro
                  50                  55                  60

 Tyr Ile Pro Lys Ala Glu Ala Tyr Glu Ser Val Val Arg Ile Glu
                  65                  70                  75

 Gly Ser Leu Gly Gln Val Ala Val Ser Thr Cys Phe Ser Pro Arg
                  80                  85                  90

 Arg Ala Ile Asp Ala Val Pro His Gly Thr Gln Glu Gln Asp Ile
                  95                 100                 105

 Glu Ala Ala Ser Ser Gln Arg Leu Arg Val Leu Tyr Arg Ile Glu
                 110                 115                 120

 Lys Met Phe Leu Gln Leu Leu Glu Ile Glu Glu Gly Trp Lys Tyr
                 125                 130                 135

 Arg Pro Pro Pro Pro Cys Phe Ser Glu Gln Gln Ser Asn Gln Val
                 140                 145                 150

 Glu Lys Leu Phe Gln Thr Leu Lys Thr Gln Glu Gln Asn Asn Leu
                 155                 160                 165

 Glu Glu Ala Ala Asp Gly Phe Leu Gln Val Leu Ser Val Arg Lys
                 170                 175                 180

 Gly Lys Ala Leu Val Ala Arg Leu Leu Pro Phe Leu Pro Gln Asp
                 185                 190                 195

 Gln Ala Val Thr Ile Leu Leu Ala Ile Thr His His Leu Pro Leu
                 200                 205                 210

 Leu Val Arg Arg Asp Val Ala Asp Gln Ala Leu Gln Met Leu Phe
                 215                 220                 225

 Lys Pro Leu Gly Lys Cys Ile Ser His Leu Thr Leu His Glu Leu
                 230                 235                 240

 Leu Gln Gly Leu Gln Gly Leu Thr Leu Leu Pro Pro Gly Ser Ser
                 245                 250                 255

 Glu Arg Pro Val Thr Val Val Leu Gln Asn Gln Phe Gly Ile Ser
                 260                 265                 270

 Leu Leu Tyr Ala Leu Leu Ser His Gly Glu Gln Leu Val Ser Leu
                 275                 280                 285

 His Ser Ser Leu Glu Glu Pro Asn Ser Asp His Thr Ala Trp Thr
                 290                 295                 300

 Asp Met Val Val Leu Ile Ala Trp Glu Ile Ala Gln Met Pro Thr
                 305                 310                 315

 Ala Ser Leu Ala Glu Pro Leu Ala Phe Pro Ser Asn Leu Leu Pro
                 320                 325                 330

 Leu Phe Cys His His Val Asp Lys Gln Leu Val Gln Gln Leu Glu
                 335                 340                 345

 Ala Arg Met Glu Phe Ala Trp Ile Tyr
                 350

<210> 4827
<211> 1725
<212> DNA
<213> Homo sapien

<400> 4827
 ggggaggtag cacaaaggga ggaccatggt cttctaactg aggaacctga 50

 gcagatgcct tgacccagac cagagaccca agccaaggaa agcccatgat 100

 caccagagta atggggatat gaaggaagaa tcagctgcac aattaggttg 150

 ttgtcatagg cccatggccc tgggaggtac agggggctcc ctgtccccca 200

 gcctggactt ccagctcttc cgaggtgacc aggtcttctc agcctgcaga 250

 ccacttccag acatggtgga tgctcatggc ccatcctgtg ccagctggct 300

 gtgtcccttg cccctggcac cgggcaggtc tgcactgctg gcctgcctac 350

 aggacctgga cctgaacctg tgcaccccac agccggcacc cctgggcaca 400

 gacctgcagg gcctccaaga ggacgccttg agcatgaagc acgagccacc 450

 agggctgcag gccagctcca ccgatgacaa gaaattcaca gtcaagtacc 500

 cacagaacaa ggacaagctg ggaaaacagc cagaaagagc tggcgagggg 550

 gccccctgcc cagccttctc ctctcataac agctcttccc caccaccgct 600

 gcagaacaga aagagcccca gccccttggc tttctgcccc tgtccccctg 650

 tcaactccat ctccaaggag ctcccatttc tcctccacgc cttctaccct 700

 ggatacccac ttctcctgcc tccacccaac ctgttcacct atggggccct 750

 accttctgac caatgtcccc acctcctcat gctgccccaa gacccctcct 800

 accccaccat ggctatgcct agcctgctga tgatggtcaa tgagctgggg 850

 caccccagcg ctcggtggga gaccctgctt ccctacccag gggccttcca 900

 agcctctggc caagctctgc cttcccaggc ccgaaatcca ggtgctggag 950

 ctgccccaac cgactcccca ggcctggagc gtggtggcat ggcatctcca 1000

 gcaaagcggg tcccattgag ttcccagaca ggcaccgcag ccttgcctta 1050

 cccgctgaaa aagaagaatg gcaaaatcct gtacgagtgc aacatatgtg 1100

 gcaagagctt tgggcagctc tccaatctca aggtccacct gcgtgtgcac 1150

 agtggagagc gtccattcca gtgtgccttg tgccagaaga gcttcactca 1200

 acttgcccac ctgcagaagc accacctggt gcacactggg gagcggcccc 1250

 acaagtgctc gataccgtgg gttccaggaa gaaatcactg gaaaagcttc 1300

 caggcctgga gggaaagaga ggtgtgccac aagcgcttca gcagctccag 1350

 taacctcaag acccacctgc gcctgcactc cggggcccgg cccttccagt 1400

 gcagtgtctg ccggagtcgc ttcacccagc acatccacct gaagctgcac 1450

 catcggctgc atgccccaca gccctgtggc ctggtgcaca cccagctgcc 1500

 cctggcctct ctggcctgcc ttgcccaatg gcaccagggg gcactagatc 1550

 ttatggcggt ggcatctgag aaacacatgg gctatgacat agatgaggtc 1600

 aaagtgtcct cgacatccca ggggaaagca agagcagtga gcctgagcag 1650

 tgccgggact cccctggtga tggggcagga ccagaacaat taaaaatgtt 1700

 tcttctgtca aaaaaaaaaa aaaaa 1725

<210> 4828
<211> 509
<212> PRT
<213> Homo sapien

<400> 4828
 Met Ala Leu Gly Gly Thr Gly Gly Ser Leu Ser Pro Ser Leu Asp
   1               5                  10                  15

 Phe Gln Leu Phe Arg Gly Asp Gln Val Phe Ser Ala Cys Arg Pro
                  20                  25                  30

 Leu Pro Asp Met Val Asp Ala His Gly Pro Ser Cys Ala Ser Trp
                  35                  40                  45

 Leu Cys Pro Leu Pro Leu Ala Pro Gly Arg Ser Ala Leu Leu Ala
                  50                  55                  60

 Cys Leu Gln Asp Leu Asp Leu Asn Leu Cys Thr Pro Gln Pro Ala
                  65                  70                  75

 Pro Leu Gly Thr Asp Leu Gln Gly Leu Gln Glu Asp Ala Leu Ser
                  80                  85                  90

 Met Lys His Glu Pro Pro Gly Leu Gln Ala Ser Ser Thr Asp Asp
                  95                 100                 105

 Lys Lys Phe Thr Val Lys Tyr Pro Gln Asn Lys Asp Lys Leu Gly
                 110                 115                 120

 Lys Gln Pro Glu Arg Ala Gly Glu Gly Ala Pro Cys Pro Ala Phe
                 125                 130                 135

 Ser Ser His Asn Ser Ser Ser Pro Pro Pro Leu Gln Asn Arg Lys
                 140                 145                 150

 Ser Pro Ser Pro Leu Ala Phe Cys Pro Cys Pro Pro Val Asn Ser
                 155                 160                 165

 Ile Ser Lys Glu Leu Pro Phe Leu Leu His Ala Phe Tyr Pro Gly
                 170                 175                 180

 Tyr Pro Leu Leu Leu Pro Pro Pro Asn Leu Phe Thr Tyr Gly Ala
                 185                 190                 195

 Leu Pro Ser Asp Gln Cys Pro His Leu Leu Met Leu Pro Gln Asp
                 200                 205                 210

 Pro Ser Tyr Pro Thr Met Ala Met Pro Ser Leu Leu Met Met Val
                 215                 220                 225

 Asn Glu Leu Gly His Pro Ser Ala Arg Trp Glu Thr Leu Leu Pro
                 230                 235                 240

 Tyr Pro Gly Ala Phe Gln Ala Ser Gly Gln Ala Leu Pro Ser Gln
                 245                 250                 255

 Ala Arg Asn Pro Gly Ala Gly Ala Ala Pro Thr Asp Ser Pro Gly
                 260                 265                 270

 Leu Glu Arg Gly Gly Met Ala Ser Pro Ala Lys Arg Val Pro Leu
                 275                 280                 285

 Ser Ser Gln Thr Gly Thr Ala Ala Leu Pro Tyr Pro Leu Lys Lys
                 290                 295                 300

 Lys Asn Gly Lys Ile Leu Tyr Glu Cys Asn Ile Cys Gly Lys Ser
                 305                 310                 315

 Phe Gly Gln Leu Ser Asn Leu Lys Val His Leu Arg Val His Ser
                 320                 325                 330

 Gly Glu Arg Pro Phe Gln Cys Ala Leu Cys Gln Lys Ser Phe Thr
                 335                 340                 345

 Gln Leu Ala His Leu Gln Lys His His Leu Val His Thr Gly Glu
                 350                 355                 360

 Arg Pro His Lys Cys Ser Ile Pro Trp Val Pro Gly Arg Asn His
                 365                 370                 375

 Trp Lys Ser Phe Gln Ala Trp Arg Glu Arg Glu Val Cys His Lys
                 380                 385                 390

 Arg Phe Ser Ser Ser Ser Asn Leu Lys Thr His Leu Arg Leu His
                 395                 400                 405

 Ser Gly Ala Arg Pro Phe Gln Cys Ser Val Cys Arg Ser Arg Phe
                 410                 415                 420

 Thr Gln His Ile His Leu Lys Leu His His Arg Leu His Ala Pro
                 425                 430                 435

 Gln Pro Cys Gly Leu Val His Thr Gln Leu Pro Leu Ala Ser Leu
                 440                 445                 450

 Ala Cys Leu Ala Gln Trp His Gln Gly Ala Leu Asp Leu Met Ala
                 455                 460                 465

 Val Ala Ser Glu Lys His Met Gly Tyr Asp Ile Asp Glu Val Lys
                 470                 475                 480

 Val Ser Ser Thr Ser Gln Gly Lys Ala Arg Ala Val Ser Leu Ser
                 485                 490                 495

 Ser Ala Gly Thr Pro Leu Val Met Gly Gln Asp Gln Asn Asn
                 500                 505

<210> 4829
<211> 2285
<212> DNA
<213> Homo sapien

<400> 4829
 attacactgg attaggtgtt acgaagtaat ttagagacta tttaaagtac 50

 acgggaggat gtgcatagtt atgtgcaaat actacgccca ctttctatga 100

 gagacttgag caacctggat tttggtatcg gcgggggccc tggaccaatc 150

 ccctctcagt tctaccgagg gagaactgtt ttgtttcttc cagcacggct 200

 ttgaccgaca gtgtgttggg attcgctgac gtccatgaga aagcttggca 250

 gcatgctgag accaattttc ccagggccag aattctcctg tgtgagctaa 300

 aatacagtgg ctcggtccaa caaaacagag cctggagcca ggaattatgg 350

 cgaacctgct ccctcccgtc ctcccttggc gcacagatcc ctggcgccgc 400

 cgctcttgag gtcgcctctc gcgtgtcgac ctcatcgtcg gaacggcgct 450

 tcctgaagct ttatataagc acggctctga atccgctcgt cgggattaaa 500

 tcctgcgctg gcgcgctcct gccagtctct ggcctccatt tgctcttcct 550

 gaggctccct ccagagacct ttcccttagc ctcagtgcaa tgccttccgg 600

 gcgtcctcag accagacaca ggccaaagcc actacagaat ccggaagccc 650

 cggttgggat ctgaattctc ccggggactg tggcgtagcg gttaaaaaaa 700

 aaaaagagtg agagggacct gagcagagtg gaggaggagg gagaggaaaa 750

 cagaaaagaa atgacgaaat gtcgagaggg cggggacaat tgagaacgct 800

 tcccgccggc gcgctttcgg ttttcaatct ggtccgatac tcttgtatat 850

 caggggaaga cggtgctcgc cttgacagaa gctgtctatc gggctccagc 900

 ggtcatgtcc ggcagaggaa agggcggaaa aggcttaggc aaagggggcg 950

 ctaagcgcca ccgcaaggtc ttgagagaca acattcaggg catcaccaag 1000

 cctgccattc ggcgtctagc tcggcgtggc ggcgttaagc ggatctctgg 1050

 cctcatttac gaggagaccc gcggtgtgct gaaggtgttc ctggagaatg 1100

 tgattcggga cgcagtcacc tacaccgagc acgccaagcg caagaccgtc 1150

 acagccatgg atgtggtgta cgcgctcaag cgccaggggc gcaccctgta 1200

 cggcttcgga ggctaggccg ccgctccagc tttgcacgtt tcgatcccaa 1250

 aggccctttt tagggccgac cacttgctca tctgaggagt tggacacttg 1300

 actgcgtaaa gtgcaacagt aacgatgttg gaaggtaact ttggcagtgg 1350

 ggcgacaatc ggatctgaag ttaacggaaa gctaccgcgg cccatagcgc 1400

 tcacagccgt aaagacttaa gtcgttgacc gaaagcggct ttttcactta 1450

 cctgggcttt tttttttttt tttttttttt ttaaagcctt tatcggtatg 1500

 aaaggttgaa tgctctaggt ttgagcactg ctttctcggc ttgctcttct 1550

 ggtgcagtat aggcacacct agagggccac gtcagtcttt gcgatcacca 1600

 aatctggttc tgagaaatag gcactggcaa tttacacatg ccttgctgtg 1650

 taatctcact atatttgctc aggcaaagtg ggagaagcag ccttaggttt 1700

 tcattctaga gatgccggct ttcccacctg atcggcttag agttcacgat 1750

 tgactgtttt gggcttcatt tcaccctcta cataacaagc gggtggacta 1800

 gatgccttag caagggtccg tgttgtgtgg tgtctccagc cacgcactca 1850

 gctcaatctt agcacagtta aaaaatgcct ttctagcaag ttatctgccc 1900

 agtgcctgaa aagtatcatt tcttgtgttc aataaaaagc ctcctaattt 1950

 aatcaaggac ctatgagata actgtctttt agttgtggca ttgcaaggat 2000

 acaaatgcag agatatttta aagtgatcct tctgtaagag tgaaccaacg 2050

 atatgatctg aaagcaactt cacaggtaat tcaggtatgt gacttctacc 2100

 tcttagggcc tgttgtagct tagaatgaga gacctgcaga aacatgccca 2150

 ccatcaatac agaaagcaca atttaatttt gacaaggcca aaagccaatt 2200

 ctgtatcagc atggcgtata ttacagcaag ctattcttta cgctaccacc 2250

 tctaaattgc cctaatttgg attaaaatgt gggtt 2285

<210> 4830
<211> 10
<212> PRT
<213> Homo sapien

<400> 4830
 Leu His Trp Ile Arg Cys Tyr Glu Val Ile
   1               5                  10

<210> 4831
<211> 1634
<212> DNA
<213> Homo sapien

<400> 4831
 ggagcacagg gcgagctctc ctccgccctg cagcctcagg taaggatccg 50

 gaccttcact gctgccccaa ctggggctcc tcagctcggg gcctctaggg 100

 gcttgggctg ctggtctggg tggaggcgcg ttgggggtgt cgaggagctt 150

 gggtgcaagc cccatgcggg aagctcaggg caaagcgcct tgaaaccctc 200

 tctagtgaag gaaggtaaaa tggctccggg accccaggcg gggaaagagg 250

 tgtccaagga ggagggctgg agagtaaggc ggggatggca gagggtacgc 300

 agaggctgag aagtgggacc agtgtctcaa ggggcgccag cctcttcctc 350

 cgcccaacat ggccaccatt tttgttggga tagccttggg ctcctgccag 400

 gggaacagca gggcagtgag ggagtcagga ctttgggctg gtggggaggc 450

 cgagaatcaa ggctctgggg agtcaggact ttggggctgg tggagtggct 500

 ggggactgag gccctggggg gtcaggacct tgggctgcta tggaggctgg 550

 gactgaggct ctgggggagt caggaccttg agctggtggg gaggctggga 600

 attgaggccc tggtgtgttc aagaccttgg gctggtgggg aggccagggc 650

 ctgaggccct ggggggtcag gaccctgggc tgttggggag gctggggact 700

 taggccctgg ggggtcagga tcttgggctg gtggggaggc tgaagggtgg 750

 ggactgaggc tctgggcagt caggacctca gggttggggt ggactggaga 800

 ccaagacctt ggcaggggag ctgtggctgc ctcatttgga cgctggaggg 850

 tggctagcgt ggctggaagc ggccagccag gggttcacag aactgaaggt 900

 gaggcctcca gaggccctag tctctacctg agtgtctctg aaactggggg 950

 gatggggtgg agcctttagg gggaagggaa gagggaactg aagaggaagt 1000

 gggggaggga ggtagaggag gcaagtctgg cgccatgctg agtcaccgcc 1050

 cacaaggccc agggcgggcc ctcggggggc cctggcaggg ttggggggat 1100

 cttaggaagc cacaaggagg gctggggggc tcttggagca ggagtcagga 1150

 ggcctgggca gcctgaagag tacacgccga cggacataca gacagtgcag 1200

 tcacccataa agtagaaagc actactaaca gcactggagg gtgtagtgtt 1250

 tcctacttta tggatgagtg tactgtgggc ttcggagatc acgccactgc 1300

 tgccgcccgc tgcccgccac catcttcctc ggcgctcggg gacctcgtgt 1350

 gacaggtgag caccttacgg cccctcccta ccctgcccag atgcctgaaa 1400

 ggcctccatg gctttcctgc ccttcctggt tccggacagc tggggaaagg 1450

 ccacagcagc tcctctgctg ccctgcagtc tttgggggcg gggagggctg 1500

 gacatgtgga accctgatgc agccgcagcg tcaaggacga ggaaggggtg 1550

 ggaagggatg gtacgtggag gggaatgggt ggtgggacca gggacccaat 1600

 gctaataaag actggactgt gcttctcaaa aaaa 1634

<210> 4832
<211> 102
<212> PRT
<213> Homo sapien

<400> 4832
 Gly Ala Gln Gly Glu Leu Ser Ser Ala Leu Gln Pro Gln Val Arg
   1               5                  10                  15

 Ile Arg Thr Phe Thr Ala Ala Pro Thr Gly Ala Pro Gln Leu Gly
                  20                  25                  30

 Ala Ser Arg Gly Leu Gly Cys Trp Ser Gly Trp Arg Arg Val Gly
                  35                  40                  45

 Gly Val Glu Glu Leu Gly Cys Lys Pro His Ala Gly Ser Ser Gly
                  50                  55                  60

 Gln Ser Ala Leu Lys Pro Ser Leu Val Lys Glu Gly Lys Met Ala
                  65                  70                  75

 Pro Gly Pro Gln Ala Gly Lys Glu Val Ser Lys Glu Glu Gly Trp
                  80                  85                  90

 Arg Val Arg Arg Gly Trp Gln Arg Val Arg Arg Gly
                  95                 100

<210> 4833
<211> 1747
<212> DNA
<213> Homo sapien

<400> 4833
 tataaaagca tacttgacat aggtggagct ttttcttttg aaaatatata 50

 ttcacaattt taatatttta atttattttt tactatttaa ccctgtactt 100

 ggcaatgctc aggcagctga ttgtgaaata ttcttgtcct ttacagaaca 150

 tggttgttat tgtgctgttg acatgaatag accatggaaa cattttcatc 200

 attattattc agcctgtgct gtagttaatg ttaagttgct gaaataaaaa 250

 gtgagcaagt aatagatttt cttggcaaat ctaatgattc agcccacagg 300

 actgttgaaa ctactgcgga agtttttcta tctgaaagaa ggtgctgggc 350

 attcaaatgt gttcatgtat tgtatatcat atgaattgta tatcaattac 400

 taatgggaat ttctacatat atgcttacaa aagcaattta tttaagtaat 450

 gctaggggta gtgtacatac caattagtta ttcagctact atacagaaaa 500

 aggatgaaca aattaattta tttctaattg agccagttag acataatgca 550

 tataacgtga tatttggttc atgaaagagt tgttttcatg tggttattgt 600

 agggagtata tataattgtg gaaggggtat gggaagagtt gtgtatagtt 650

 agttgttatc tctacaagtt tgaaagtttt cccatcaaac attatcaata 700

 taccaatgtt ttaaaaattg agtgagggtt attatttgta tttgatgaaa 750

 gaaaatccaa ataaagccca cctagaaata gatattttat tatatatgtg 800

 ctatagatat acctatatag tacaaataga catgtgtgat gcatatatac 850

 aatgttatat atgtgtatat gtctgtatac acactgagtc tgtaatatgt 900

 atacactaaa tttgtgttat gctaacatct tcagggtctg cactgtgaac 950

 tcccctggag ataagtaagt ccactttaga ataaagaagt tcttttgaga 1000

 cttcagttac taacgtgctt taagaggtat ctactttata actgaattct 1050

 atgtcgttca tacgtagagt tacagtaagg gtctagtatg tccaaatctt 1100

 aataataaag aagaaaagta aaggcttcaa gctagcaatg tattcgaatt 1150

 acagttttca gattgtggct ccaggccttg tgtttctcat ttaagtagca 1200

 ccttttaata aaaaccgttt ctttgtgtag gcaaaagcac aagtgtttca 1250

 aatgtaaata gcaggaaaaa aaaagagttt acagagatag cattgctgca 1300

 gagaataatt gctactgagt atttcttata gaatttgtgg aactgaaaga 1350

 tgaggtttat tctgtcaagt tcaagttcat tctgttcaac actgttttct 1400

 tattgtttgt gtatagcaac cgggtattat tgttttatca tttgtaaaat 1450

 tgtaaaataa attaatccct ttttttcact gtttctctta tctcatatat 1500

 ccaagccctt ggttatactt tgtatgtcaa tgttaggtga tcatttttaa 1550

 caagctttgg cttgtgcttt gcttttccac tccccttagc cctagtggtt 1600

 ggcaattagg caaaccattt atttttaagt gtatacatgg gaatatgaac 1650

 aatgtcaaaa accccatgaa tattaggaaa tccttaacga tattttgtgt 1700

 agcacattct gtttgcggtt gagggaataa agtatttcac aagtgaa 1747

<210> 4834
<211> 20
<212> PRT
<213> Homo sapien

<400> 4834
 Tyr Lys Ser Ile Leu Asp Ile Gly Gly Ala Phe Ser Phe Glu Asn
   1               5                  10                  15

 Ile Tyr Ser Gln Phe
                  20

<210> 4835
<211> 2876
<212> DNA
<213> Homo sapien

<400> 4835
 cccatcttag agcagctgaa taatttcctg agaattctat tcctgaagct 50

 aggaagaaaa gtttatttat acatacacgc aacctgcaag tctccagttt 100

 ctattcttcc ttcctctttg acccttcccc tcccccactt tgcaccagag 150

 aagtcagact ccgggagtgc tttaacagtt tgaaggctaa tctgaaagag 200

 gaagaagaat ctgtatatct gtatatattg gctagcaaat gtgccctgct 250

 ctctcccctc ttaaaaatag cagcaaccca tctttgcaaa gaagcttgcc 300

 tatagagcag gcactctgtg aatggactgt gcttttacga ccctacaggg 350

 tatcaagata ctgtgcagct cgccaacaag gattaattgc aaggactggt 400

 agatcgaatt tactgaagac ttggagcttg cttctgagaa caaacgcaaa 450

 aggacagtaa actgtggacc ttgaagttag cagcgtgggc ttcctctaat 500

 attacaccgt aaaaggcatt gatcaccata agaaggaaca tttgtgaagg 550

 tactccagtg ccagaaagag gcacaaagca gacattcgta gagaaacatg 600

 gatgaaacag gaaatctgac agtatcttct gccacatgcc atgacactat 650

 tgatgacttc cgcaatcaag tgtattccac cttgtactct atgatctctg 700

 ttgtaggctt ctttggcaat ggctttgtgc tctatgtcct cataaaaacc 750

 tatcacaaga agtcagcctt ccaagtatac atgattaatt tagcagtagc 800

 agatctactt tgtgtgtgca cactgcctct ccgtgtggtc tattatgttc 850

 acaaaggcat ttggctcttt ggtgacttct tgtgccgcct cagcacctat 900

 gctttgtatg tcaacctcta ttgtagcatc ttctttatga cagccatgag 950

 ctttttccgg tgcattgcaa ttgtttttcc agtccagaac attaatttgg 1000

 ttacacagaa aaaagccagg tttgtgtgtg taggtatttg gatttttgtg 1050

 attttgacca gttctccatt tctaatggcc aaaccacaaa aagatgagaa 1100

 aaataatacc aagtgctttg agcccccaca agacaatcaa actaaaaatc 1150

 atgttttggt cttgcattat gtgtcattgt ttgttggctt tatcatccct 1200

 tttgttatta taattgtctg ttacacaatg atcattttga ccttactaaa 1250

 aaaatcaatg aaaaaaaatc tgtcaagtca taaaaaggct ataggaatga 1300

 tcatggtcgt gaccgctgcc tttttagtca gtttcatgcc atatcatatt 1350

 caacgtacca ttcaccttca ttttttacac aatgaaacta aaccctgtga 1400

 ttctgtcctt agaatgcaga agtccgtggt cataaccttg tctctggctg 1450

 catccaattg ttgctttgac cctctcctat atttcttttc tgggggtaac 1500

 tttaggaaaa ggctgtctac atttagaaag cattctttgt ccagcgtgac 1550

 ttatgtaccc agaaagaagg cctctttgcc agaaaaagga gaagaaatat 1600

 gtaaagtata gtttaaaccc atttccagtc caaaccaatg aaaatagttt 1650

 cccaaataag tattttgtca aatcatttac aaaaaaaata aaaattttac 1700

 ttaatatttt acaaatactt aactatttgg gcctacaact ctatctcatt 1750

 tatgcatcca catgattaga tatttataga tattttaagt gctaaaaatt 1800

 cggtccacaa ctatgaactg aattataaat aattttgacc actcaccaga 1850

 atttggagaa tatttttatc tttgcactat aaaatatgtc ttatattaaa 1900

 gttttcctct tcaaataaaa gctttacaaa cgataaaata tataaaatta 1950

 gtcaataaaa atacatgcaa gctaaaagtt ataaaatata aaactagata 2000

 taaaattggc aaatagttct gaatcattct aacatattcc tttgcatgca 2050

 tgccatcaga tgagaactgg agatgactca ggagctacat aaaacgtact 2100

 gtcacccttc tttgtagtac tgattcgcta ggcaaattag ggccatttct 2150

 tccaaaagag aatgtaaaag tgctagaaca gactagtatt cagctaaagg 2200

 gtcctaaaag caccatacaa tgttcaatat ggcaacagga gaaatctggt 2250

 caaaagccag tttgtctcca gttttcttct gcctttgcct caggctccca 2300

 aaattgaata gtggagtttt agctgctcag tgaggttcct gtagagattt 2350

 ctctccatcc atgacataca attcttcctt aagaagccag acaactggca 2400

 ctcctatata taaatagaag taattaaaaa cttatctgaa gaagagaaaa 2450

 ggaaaaggaa tctacttttc tatatgccaa ttgctgggat caaaataaac 2500

 tacaaaggat ttatgaagaa aattgtgaat gttcacgtta caaattcttt 2550

 taagaagtgc atacatttat gtatatgtat acaactatat gtaagagatt 2600

 ttgctgtatg atatgcatta tgggtgaaag ttcacgataa gttttattat 2650

 tgctttatta ctttttattg gtatgttgac aggaatatca tggatatgtt 2700

 tacagtgact tttatattac agtggacgct ttgatcttaa aacagccaca 2750

 acaactcatc tacggctgaa atataatatg cgtggacaag cttttgctga 2800

 agtgtagtgt gtcctttaag tttgtttttt aaaaagtaac ttacctcaga 2850

 agaaataaat gataactata aagaaa 2876

<210> 4836
<211> 306
<212> PRT
<213> Homo sapien

<400> 4836
 Met Ile Ser Val Val Gly Phe Phe Gly Asn Gly Phe Val Leu Tyr
   1               5                  10                  15

 Val Leu Ile Lys Thr Tyr His Lys Lys Ser Ala Phe Gln Val Tyr
                  20                  25                  30

 Met Ile Asn Leu Ala Val Ala Asp Leu Leu Cys Val Cys Thr Leu
                  35                  40                  45

 Pro Leu Arg Val Val Tyr Tyr Val His Lys Gly Ile Trp Leu Phe
                  50                  55                  60

 Gly Asp Phe Leu Cys Arg Leu Ser Thr Tyr Ala Leu Tyr Val Asn
                  65                  70                  75

 Leu Tyr Cys Ser Ile Phe Phe Met Thr Ala Met Ser Phe Phe Arg
                  80                  85                  90

 Cys Ile Ala Ile Val Phe Pro Val Gln Asn Ile Asn Leu Val Thr
                  95                 100                 105

 Gln Lys Lys Ala Arg Phe Val Cys Val Gly Ile Trp Ile Phe Val
                 110                 115                 120

 Ile Leu Thr Ser Ser Pro Phe Leu Met Ala Lys Pro Gln Lys Asp
                 125                 130                 135

 Glu Lys Asn Asn Thr Lys Cys Phe Glu Pro Pro Gln Asp Asn Gln
                 140                 145                 150

 Thr Lys Asn His Val Leu Val Leu His Tyr Val Ser Leu Phe Val
                 155                 160                 165

 Gly Phe Ile Ile Pro Phe Val Ile Ile Ile Val Cys Tyr Thr Met
                 170                 175                 180

 Ile Ile Leu Thr Leu Leu Lys Lys Ser Met Lys Lys Asn Leu Ser
                 185                 190                 195

 Ser His Lys Lys Ala Ile Gly Met Ile Met Val Val Thr Ala Ala
                 200                 205                 210

 Phe Leu Val Ser Phe Met Pro Tyr His Ile Gln Arg Thr Ile His
                 215                 220                 225

 Leu His Phe Leu His Asn Glu Thr Lys Pro Cys Asp Ser Val Leu
                 230                 235                 240

 Arg Met Gln Lys Ser Val Val Ile Thr Leu Ser Leu Ala Ala Ser
                 245                 250                 255

 Asn Cys Cys Phe Asp Pro Leu Leu Tyr Phe Phe Ser Gly Gly Asn
                 260                 265                 270

 Phe Arg Lys Arg Leu Ser Thr Phe Arg Lys His Ser Leu Ser Ser
                 275                 280                 285

 Val Thr Tyr Val Pro Arg Lys Lys Ala Ser Leu Pro Glu Lys Gly
                 290                 295                 300

 Glu Glu Ile Cys Lys Val
                 305

<210> 4837
<211> 535
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 103
<223> Unknown base

<400> 4837
 tatcccagag agtttttgag catatgggta gtgtttgtga atttaagttt 50

 gttccccaca ttgtcagttt attctaaaat tatcaccatt ttagacttaa 100

 agnaatttta aagccaaaag ataagcaaac agacttgctt aggtcctgta 150

 gcaaattaat tcagaccttg aacaacattt cattgtgctg tttaggaagt 200

 gttaagtata ttgagatttt ccatattact gtgttactat catacttaaa 250

 ttttagaaga tgatcaaatt attttaatga ctaggactat gcttatgaag 300

 ttagcatttc ctgcccttat ttatagaaag cacttgatat atttcacaaa 350

 ggtgaggaga ttaacttttt agggaacaag tcatttaaat tcttgaacca 400

 gtttccatct tttaggctat atgagtattg aatataggag aaaagagaaa 450

 agtatgcatg tttctcaaag gctctttctt taaatgtcac cagcagatct 500

 aaacagtatc cataggcacc tatggcaaat ttact 535

<210> 4838
<211> 1419
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 214-291
<223> Unknown base

<400> 4838
 cccattctct tcctctacct cactccatct gataaaaaac cattctaaat 50

 ctcatgttca ttattcccat gctctcctat ttctatcata ttaatgtatc 100

 tacatgtttt ccttaaatat gtttttatat tagttttaac tataagttaa 150

 agaccatatt gttgtagata atttttttta gtactttctc ttcatgttgt 200

 atttctaaga ttcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn naatgttttc 300

 ctagctatca ccatcaaaaa ctctttccac agtgtgttga atttttaata 350

 tgacaaaaat gaaaatgtac caacaatttt cagtgacttc acctccattc 400

 tgaaatcctg atgtttccaa atatctctga acacctcaag tcctagggac 450

 aactgagatt atattaacat taatctctga atgttgccaa ttctaggcct 500

 tcacttggtt catgtaggaa caccaagtcc ctttcaaagc accacatctt 550

 cctctaatca atatttcttg gagtccctag ggaatgtctt acatgcattc 600

 aaacaatcac catttctgga gatacactac agggtcacca taaactctgc 650

 tacccttagg ttccatcact atggaagctg agtttcacca gaaggcactt 700

 ttgtcctcca ttacgaccag caaagccagc taagccacag ctgctggcct 750

 caaaaaatgt gatgatcaat ccacactgct cccactggcc tctgttaccc 800

 ttatcctggc ctttgagtgc agggcatgat gtcctgcccg tactgagatg 850

 ctgatctctg ccagttcatg ttcatattgg cattaaaatt ttaaggtccc 900

 ttgaagaggg aggaggcaaa tgtctctgtc ttctatgtga tacattctgc 950

 tgtttttttc tctatggtga aaatatgtaa accggttttg ggtaccaacc 1000

 accaggctgt atatggaggc tctcctcctt tctaaccctg ctgctgattt 1050

 ggaattacct tgccaagccc ctttgtgcct tatagtgaac tttctctaag 1100

 ggacctgtca tctcttatca ttgtttatcc attttctaga ttctgaaccc 1150

 aagaaagaac aaagttcaag attttccatg tctttgtaac acttagccct 1200

 gtgcaaatca gagtatgtga gtggaagaag gggtgagtcc taactgtaca 1250

 tctcggatat aacaaatgtg caaattctga ttgattgccc tgtaaaatga 1300

 attattctca tgcagtgctc tacttgactt ttatctttga attcacaact 1350

 aaaaacccat agcccagaaa tctaaaaaaa gtaattttag tggagccttt 1400

 gaaaataaaa gaccattgg 1419

<210> 4839
<211> 30
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 214-291
<223> Unknown amino acid

<400> 4839
 Pro Phe Ser Ser Ser Thr Ser Leu His Leu Ile Lys Asn His Ser
   1               5                  10                  15

 Lys Ser His Val His Tyr Ser His Ala Leu Leu Phe Leu Ser Tyr
                  20                  25                  30

<210> 4840
<211> 3164
<212> DNA
<213> Homo sapien

<400> 4840
 gcagccccgg cggccgaacg cccgcggcgc gggactccat cgtcagagaa 50

 gtcattcaga attcaaaaga agttctaagt ttattgcaag aaaaaaaccc 100

 tgccttcaag ccggttcttg caattatcca ggcaggtgac gacaacttga 150

 tgcaggaaat caaccagaat ttggctgagg aggctggtct gaacatcact 200

 cacatttgcc tccctccaga tagcagtgaa gccgagatta tagatgaaat 250

 cttaaagatc aatgaagata ccagagtaca tggccttgcc cttcagatct 300

 ctgagaactt gtttagcaac aaagtcctca atgccttgaa accagaaaaa 350

 gatgtggatg gagtaacaga cataaacctg gggaagctgg tgcgagggga 400

 tgcccatgaa tgttttgttt cacctgttgc caaagctgta attgaacttc 450

 ttgaaaaatc aggtgtcaac ctagatggaa agaagatttt ggtagtgggg 500

 gcccatgggt ctttggaagc tgctctacaa tgcctgttcc agagaaaagg 550

 gtccatgaca atgagcatcc agtggaaaac acgccagctt caaagcaagc 600

 ttcacgaggc tgacattgtg gtcctaggct cacctaagcc agaagagatt 650

 ccccttactt ggatacaacc aggaactact gttctcaact gctcccatga 700

 cttcctgtca gggaaggttg ggtgtggctc tccaagaata cattttggtg 750

 gactcattga ggaagatgat gtgattctcc ttgctgcagc tctgcgaatt 800

 cagaacatgg tcagtagtgg aaggagatgg cttcgtgaac agcagcacag 850

 gcggtggaga cttcactgct tgaaacttca gcctctctcc cctgtgccaa 900

 gtgacattga gatttcaaga ggacaaactc caaaagctgt ggatgtcctt 950

 gccaaggaga ttggattgct tgcagatgaa attgaaatct atggcaaaag 1000

 caaagccaaa gtacgtttgt ccgtgctaga aaggttaaag gatcaagcag 1050

 atggaaaata cgtcttagtt gctgggatca cacccacccc tcttggagaa 1100

 gggaagagca cagtcaccat cgggcttgtg caggctctga ccgcacacct 1150

 gaatgtcaac tcctttgcct gcttgaggca gccttcccaa ggaccgacgt 1200

 ttggagtgaa aggaggagcc gcgggtggtg gatatgccca ggtcatcccc 1250

 atggaggagt tcaaccttca cttgactgga gacatccacg ccatcaccgc 1300

 tgccaataac ttgctggctg ccgccatcga cacgaggatt cttcatgaaa 1350

 acacgcaaac agataaggct ctgtataatc ggctggttcc tttagtgaat 1400

 ggtgtcagag aattttcaga aattcagctt gctcggctaa aaaaactggg 1450

 aataaataag actgatccga gcacactgac agaagaggaa gtgagtaaat 1500

 ttgcccgtct cgacatcgac ccatctacca tcacgtggca gagagtattg 1550

 gatacaaatg accgatttct acgaaaaata accatcgggc agggaaacac 1600

 agagaagggc cattaccggc aggcgcagtt tgacatcgca gtggccagcg 1650

 agatcatggc ggtgctggcc ctgacggaca gcctcgcaga catgaaggca 1700

 cggctgggaa ggatggtggt ggccagtgac aaaagcgggc agcctgtgac 1750

 agcagatgat ttgggggtga caggtgcttt gacagttttg atgaaagatg 1800

 caataaaacc aaacctgatg cagaccctgg aagggacacc tgtgttcgtg 1850

 catgcgggcc cttttgctaa cattgctcac ggcaactctt cagtgttggc 1900

 tgataaaatt gccctgaaac tggttggtga agaaggattt gtagtgaccg 1950

 aagctggctt tggtgctgac atcggaatgg agaaattctt caacatcaag 2000

 tgccgagctt ccggcttggt gcccaacgtg gttgtgttag tggcaacggt 2050

 gcgagctctg aagatgcatg gaggcgggcc aagtgtaacg gctggtgttc 2100

 ctcttaagaa agaatataca gaggagaaca tccagctggt ggcagacggc 2150

 tgctgtaacc tccagaagca aattcagatc actcagctct ttggggttcc 2200

 cgttgtggtg gctctgaatg tcttcaagac cgacacccgc gctgagattg 2250

 acttggtgtg tgagcttgca aagcgggctg gtgcctttga tgcagtcccc 2300

 tgctatcact ggtccgttgg tggaaaagga tcggtggact tggctcgggc 2350

 tgtgagagag gctgcgagta aaagaagccg attccagttc ctgtatgatg 2400

 ttcaggttcc aattgtggac aagataagga ccattgctca ggctgtctat 2450

 ggagccaaag atattgaact ctctcctgag gcacaagcca aaatagatcg 2500

 ttacactcaa cagggttttg gaaatttgcc catctgcatg gcaaagaccc 2550

 acctttctct atctcaccaa cctgacaaaa aaggtgtgcc aagggacttc 2600

 atcttaccta tcagtgacgt ccgggccagc ataggcgctg ggttcattta 2650

 ccctttggtc ggaacgatga gcaccatgcc aggactgccc acccggccct 2700

 gcttttatga catagatctt gataccgaaa cagaacaagt taaaggcttg 2750

 ttctaagtgg acaaggctct cacaggaccc gatgcagact cctgaaacag 2800

 actactcttt gcctttttgc tgcagttgga gaagaaactg aatttgaaaa 2850

 atgtctgtta tgcaatgctg gagacgtggt gaaataggcc aaagatttct 2900

 tcttcgttca agatgaattc tgttcacagt ggagtatggt gttcggcaaa 2950

 aggacctcca ccaagactga aagaaactaa tttatttctg tttctgtgga 3000

 gtttccatta tttctactgc ttacacttta gaatgtttat tttatgggga 3050

 ctaagggatt aggagtgtga actaaaaggt aacattttcc actctcaagt 3100

 tttctacttt gtctttgaac tgaaaataaa catggatcta gaaaaccaaa 3150

 aaaaaaaaaa aaaa 3164

<210> 4841
<211> 1494
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 139-161, 258-335, 1126-1143
<223> Unknown base

<400> 4841
 tgggactaca ggcatgtgcc accacaccca gctaagttaa tgctaatgtg 50

 tagtttatct gattcagttt tgaagggcgg gatatatata gatagttatg 100

 ttgtgtgtgt ggtggtgggg gtagtgttta tatgtgtgnn nnnnnnnnnn 150

 nnnnnnnnnn ntactagtcc attgctgcta caacaaacta ccagtatgtc 200

 agggcataaa acaaatttat tacactcctg tatgtcagag tatgatgtgg 250

 atctcatnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnncattc tggagtctgc 350

 ctgcattttt tggctttggg ctcttctcca ctctcaccat tagcaacctt 400

 gcatcccatg gactcttctt ctatggccac atgtctctgt ggctctttcc 450

 ttcccccttc tcttccactg ttaaggactc atgtgcttac ttagtcctga 500

 atggagacac cgtcatcatc cacatgagcc cactgtccta atccatacag 550

 gctgctacaa ggaaatgcat tagaccaggt agcttataaa taacagaact 600

 ttgtttctca cagtcctgga ggctgagaag tgcaagatca aggtgccggc 650

 agtcttggtg tctggtgaag gcctgctttc tcatagaggc ttccttcttg 700

 ctgtgtcttc gcatggtgag aggaacaaac aagctccctt gtgcctttaa 750

 taaggtgcta atcccagtca tgagggcaga gtctcccgta aggcttaacc 800

 tcctaatgcc atcaccttga gggttaggat tttaacacat gaacagtgac 850

 ggaacacaac gttcattcca tagcaccagg gtagtctcct catgtcaagg 900

 tctttacctg aatcacatgc atgatgtacc gttttcatgt aaggttctag 950

 gaatctgtgg acatctttgg ggggccatta ttttgctgat cacatattac 1000

 atatttttta atattctaga ctagtatgaa aacaatgcca cttccattgc 1050

 tttatatacg tatctatata cacattgtct aatgctataa ttaaaaaaaa 1100

 gttgtagaca caaatatacc catttnnnnn nnnnnnnnnn nnnggctatt 1150

 ttacttcata ctgccaactc ctttttcctg aaactgcttc aactctggaa 1200

 ttcttttttg ctattagttt tattttattg aaatattcat gaatgagcat 1250

 acacttgtat atggatttaa aattcacagt aatgttctca tgagttcatc 1300

 tgtgaataac attttataga caaaatgtct gcactaagac aagagaaaga 1350

 tctataattc ctttgttcta aggtaccgcc attcattgtt attattttaa 1400

 aataggagtg ttgactgatg ttaaaacaca aaatgggttc gggagtggtg 1450

 gctcccgctg tagtccagca ctttgggaga ccgggtgggg cgga 1494

<210> 4842
<211> 130
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 47-54, 86-112
<223> unknown amino acid

<220>
<221> Unsure
<222> 139-161, 258-335, 1126-1143
<223> Unknown amino acid

<400> 4842
 Trp Asp Tyr Arg His Val Pro Pro His Pro Ala Lys Leu Met Leu
   1               5                  10                  15

 Met Cys Ser Leu Ser Asp Ser Val Leu Lys Gly Gly Ile Tyr Ile
                  20                  25                  30

 Asp Ser Tyr Val Val Cys Val Val Val Gly Val Val Phe Ile Cys
                  35                  40                  45

 Val Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Thr Ser Pro Leu Leu Leu
                  50                  55                  60

 Gln Gln Thr Thr Ser Met Ser Gly His Lys Thr Asn Leu Leu His
                  65                  70                  75

 Ser Cys Met Ser Glu Tyr Asp Val Asp Leu Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ile Leu Glu Ser Ala Cys Ile Phe
                 110                 115                 120

 Trp Leu Trp Ala Leu Leu His Ser His His
                 125                 130

<210> 4843
<211> 1615
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 891
<223> Unknown base

<400> 4843
 atacacatgc agaagctgtg acacgtgcgg aagctgtggt aagtgcatcc 50

 tccttcagtc tcagttctga aaatagatca tcatggtggc accaaagagt 100

 cacacagatg actgggctcc tgggcctttc tccagtaagc cacagaggag 150

 tcagctgcaa atattctctt ctgttctaca gacctctctc ctcttcctgc 200

 tcatgggccc aactcctggg aaacatctct ccgctgcatg gcccggaacc 250

 ccactgtcca gcagatagag ccaatccagt accccagaga ggatctcagc 300

 cacctgggac tgtggcagct actgtccttc tgtgctcccg ctttctccag 350

 ggcttcaggg atgatgatgc aggactaaga gcctctggaa aggactcagc 400

 cccaacagtg gtgtcaggga tcctaggggg ttccgtgact ctccccctaa 450

 acatctcagt agacacagag attgagaacg tcatctggat tggtcccaaa 500

 aatgctcttg ctttcgcacg tcccaaagaa aatgtaacca ttatggtcaa 550

 aagctacctg ggccgactag acatcaccaa gtggagttac tccctgtgca 600

 tcagcaatct gactctgaat gatgcaggat cctacaaagc ccagataaac 650

 caaaggaatt ttgaagtcac cactgaggag gaattcaccc tgttcgtcta 700

 tgcaccattt attgaaaagt tgtccgtcca cgtcatcgag ggtgaccacc 750

 gcacactcct ggagggcagc ggcctggagt ccatcatcag caccctggct 800

 gagccacgtg tgagcgtgcg ggagggctag gccctcgccc ccacctgcca 850

 ctggagaccg ctccgccatc cccacctcac cgccgcgcaa nagagctgga 900

 agggtcctgc cgatgggacc ctgccaggcc cagtgccact gccccccgag 950

 ggctgctaga cgtggggcgt taggcgtgtc ccacccaccc gccgcctccc 1000

 atgggcacgt cgggaacacc ggagccgcca acttggagac ttcctggtct 1050

 gtgaagagcc gctgacgccc gcaggaaacc ggggctgggc cttgtgtgcc 1100

 agtcggggtt ttgtgcttgg tcgtttctcc gcttggattt gcttatttat 1150

 tgcattgctg gtagagactc ccaagcctgt ccaccctgca aagactcctc 1200

 gggcagcatg cgggtcccgc acactgcacc catttcctgg atgtcccctg 1250

 caggcgcggg aggccatccg ggcctgctgg ctgcggcccc ctctcagcca 1300

 ggcctggctc agcccactgc gtgggaggtc accggccact ccccgaggag 1350

 ctgggatccc cgggatgcag gcccacagtg cggggctgca cccatgatgc 1400

 ggagctggcc tccaaccctg cgggccgcgc caggcaccaa ctcagtgttt 1450

 gtcagtgttt gtttttccaa gaaatggttc aaattgctgc tcagattttt 1500

 aaatttactg tagctgccag tgtacacgtg tggaccccat tttattttta 1550

 caccaatttg gtgaaaatgc tgctttcctc agcctcccca caattaaact 1600

 gcacatggtc tctaa 1615

<210> 4844
<211> 275
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 891
<223> Unknown amino acid

<400> 4844
 Thr His Ala Glu Ala Val Thr Arg Ala Glu Ala Val Val Ser Ala
   1               5                  10                  15

 Ser Ser Phe Ser Leu Ser Ser Glu Asn Arg Ser Ser Trp Trp His
                  20                  25                  30

 Gln Arg Val Thr Gln Met Thr Gly Leu Leu Gly Leu Ser Pro Val
                  35                  40                  45

 Ser His Arg Gly Val Ser Cys Lys Tyr Ser Leu Leu Phe Tyr Arg
                  50                  55                  60

 Pro Leu Ser Ser Ser Cys Ser Trp Ala Gln Leu Leu Gly Asn Ile
                  65                  70                  75

 Ser Pro Leu His Gly Pro Glu Pro His Cys Pro Ala Asp Arg Ala
                  80                  85                  90

 Asn Pro Val Pro Gln Arg Gly Ser Gln Pro Pro Gly Thr Val Ala
                  95                 100                 105

 Ala Thr Val Leu Leu Cys Ser Arg Phe Leu Gln Gly Phe Arg Asp
                 110                 115                 120

 Asp Asp Ala Gly Leu Arg Ala Ser Gly Lys Asp Ser Ala Pro Thr
                 125                 130                 135

 Val Val Ser Gly Ile Leu Gly Gly Ser Val Thr Leu Pro Leu Asn
                 140                 145                 150

 Ile Ser Val Asp Thr Glu Ile Glu Asn Val Ile Trp Ile Gly Pro
                 155                 160                 165

 Lys Asn Ala Leu Ala Phe Ala Arg Pro Lys Glu Asn Val Thr Ile
                 170                 175                 180

 Met Val Lys Ser Tyr Leu Gly Arg Leu Asp Ile Thr Lys Trp Ser
                 185                 190                 195

 Tyr Ser Leu Cys Ile Ser Asn Leu Thr Leu Asn Asp Ala Gly Ser
                 200                 205                 210

 Tyr Lys Ala Gln Ile Asn Gln Arg Asn Phe Glu Val Thr Thr Glu
                 215                 220                 225

 Glu Glu Phe Thr Leu Phe Val Tyr Ala Pro Phe Ile Glu Lys Leu
                 230                 235                 240

 Ser Val His Val Ile Glu Gly Asp His Arg Thr Leu Leu Glu Gly
                 245                 250                 255

 Ser Gly Leu Glu Ser Ile Ile Ser Thr Leu Ala Glu Pro Arg Val
                 260                 265                 270

 Ser Val Arg Glu Gly
                 275

<210> 4845
<211> 6478
<212> DNA
<213> Homo sapien

<400> 4845
 agagcgagca ggggagagcg agaccagttt taaggggagg accggtgcga 50

 gtaaggcagc cccgaggctc tgctcgccca ccacccaatc ctcgcctccc 100

 ttctgctcca ccttctctct ctgccctcac ctctcccccg aaaaccccct 150

 atttagccaa aggaaggagg tcaggggaac gctctcccct ccccttccaa 200

 aaaacaaaaa cagaaaaacc cttttccagg ccggggaaag caggagggag 250

 aggggccgcc gggctggcca tggagctgct gtgccacgag gtggacccgg 300

 tccgcagggc cgtgcgggac cgcaacctgc tccgagacga ccgcgtcctg 350

 cagaacctgc tcaccatcga ggagcgctac cttccgcagt gctcctactt 400

 caagtgcgtg cagaaggaca tccaacccta catgcgcaga atggtggcca 450

 cctggatgct ggaggtctgt gaggaacaga agtgcgaaga agaggtcttc 500

 cctctggcca tgaattacct ggaccgtttc ttggctgggg tcccgactcc 550

 gaagtcccat ctgcaactcc tgggtgctgt ctgcatgttc ctggcctcca 600

 aactcaaaga gaccagcccg ctgaccgcgg agaagctgtg catttacacc 650

 gacaactcca tcaagcctca ggagctgctg gagtgggaac tggtggtgct 700

 ggggaagttg aagtggaacc tggcagctgt cactcctcat gacttcattg 750

 agcacatctt gcgcaagctg ccccagcagc gggagaagct gtctctgatc 800

 cgcaagcatg ctcagacctt cattgctctg tgtgccaccg actttaagtt 850

 tgccatgtac ccaccgtcga tgatcgcaac tggaagtgtg ggagcagcca 900

 tctgtgggct ccagcaggat gaggaagtga gctcgctcac ttgtgatgcc 950

 ctgactgagc tgctggctaa gatcaccaac acagacgtgg attgtctcaa 1000

 agcttgccag gagcagattg aggcggtgct cctcaatagc ctgcagcagt 1050

 accgtcagga ccaacgtgac ggatccaagt cggaggatga actggaccaa 1100

 gccagcaccc ctacagacgt gcgggatatc gacctgtgag gatgccagtt 1150

 gggccgaaag agagagacgc gtccataatc tggtctcttc ttctttctgg 1200

 ttgtttttgt tctttgtgtt ttagggtgaa acttaaaaaa aaaattctgc 1250

 ccccacctag atcatattta aagatctttt agaagtgaga gaaaaaggtc 1300

 ctacgaaaac ggaataataa aaagcatttg gtgcctattt gaagtacagc 1350

 ataagggaat cccttgtata tgcgaacagt tattgtttga ttatgtaaaa 1400

 gtaatagtaa aatgcttaca ggaaaacctg cagagtagtt agagaatatg 1450

 tatgcctgca atatgggaac aaattagagg agactttttt tttcatgtta 1500

 tgagctagca catacacccc cttgtagtat aatttcaagg aactgtgtac 1550

 gccatttatg gcatgattag attgcaaagc aatgaactca agaaggaatt 1600

 gaaataagga gggacatgat ggggaaggag tacaaaacaa tctctcaaca 1650

 tgattgaacc atttgggatg gagaagcacc tttgctctca gccacctgtt 1700

 actaagtcag gagtgtagtt ggatctctac attaatgtcc tcttgctgtc 1750

 tacagtagct gctacctaaa aaaagatgtt ttattttgcc agttggacac 1800

 aggtgattgg ctcctgggtt tcatgttctg tgacatcctg cttcttcttc 1850

 caaatgcagt tcattgcaga caccaccata ttgctatcta atggggaaat 1900

 gtagctatgg gccataacca aaactcacat gaaacggagg cagatggaga 1950

 ccaagggtgg gatccagaat ggagtctttt ctgttattgt atttaaaagg 2000

 gtaatgtggc cttggcattt cttcttagaa aaaaactaat ttttggtgct 2050

 gattggcatg tctggttcac agtttagcat tgttataaac cattccattc 2100

 gaaaagcact ttgaaaaatt gttcccgagc gatagatggg atggtttatg 2150

 caagtcatgc tgaatactcc tcccctcttc tcttttgccc cctcccttcc 2200

 tgcccccagt ctgggttact cttcgcttct ggtatctggc gttctttggt 2250

 acacagttct ggtgttccta ccaggactca agagacaccc cttcctgctg 2300

 acattcccat cacaacattc ctcagacaag cctgtaaact aaaatctgtt 2350

 accatctgat ggcacagaag gatcttaatt cccatctcta tacttctcct 2400

 ttggacatgg aaagaaaagt tattgctggt gcaaagatag atggctgaac 2450

 atcagggtgt ggcattttgt tcccttttcc gttttttttt tttttattgt 2500

 tgttgttaat tttattgcaa agttgtattc agcgtacttg aatttttctt 2550

 cctctccact tcttagaggc attcagttag caaagaggtt ggagcaacaa 2600

 cttttttttt ttttttttgc acaattgtaa ttgacaggta atgaagctat 2650

 ttgttaaaat atttgccttt ttaagtaaaa aagaaaaatc agaacagggc 2700

 tatttgaaga attattttat acacagattc tgccttgttt catagtatga 2750

 gggttgaaga cggaaaacaa tctaagggtc tctcattttt ttaattttgt 2800

 tttgttcagt ttggtttttt tttttttttg cgctgctaag aagctaaagt 2850

 catccatcct tattcacgtt gacagtacct agctgtaatg tttcacagag 2900

 tgtgctgcta ttttataaac atttttataa tatattattt tactgcttaa 2950

 attccaagtc ctgaagtaga tggttgagat atgagttctt cgtactggaa 3000

 aagcccttcc gtagtttgtt ttcttctggt agcatattca tggttgtttt 3050

 tttttttctt ttttggtttt ttggtttttt ttttttcctc tgatcacatt 3100

 cttcaaagac ggagtattct tacctcaggt ttactggaca aaatcaataa 3150

 ctacaaaagg caatgattca cgcttttgtt ttcataatac ctcacaaccg 3200

 tacagtttct gcttgggagc ccattcgcat gaggaataca gaagcagtgt 3250

 gagcagggct gactccctct caggtggaag gcagggcggt ctcactccca 3300

 gggacctttt tggtcatgga ggccatcggg ctcccagtta gaccctggta 3350

 tcctcatcat gatggaaaaa atacattgaa ccaagggatc ctccctcccc 3400

 ttcaaggcag acgttcagta caaacattta tgcggtaggc tcagatgtcg 3450

 taatttgcac ttaggtacca ggtgtcagga aacagactaa aaagaattcc 3500

 accaggctgt ttggagatcc tcatcttgga gctttttcaa aagcggggct 3550

 tcatctgcaa agggcccttt catcttgaag tttttcccct ccgtctttcc 3600

 cctcccctgg catggacacc ttgtgtttag gatcatctct gcaggtttcc 3650

 taggtctgaa tctgcgagta gatgaacctg cagcaagcag cgtttatggt 3700

 gcttccttct ccctcctctg tctcaaactg cgcaggcaag cactatgcaa 3750

 gcccaggccc tctgctgagc ggtactaaac ggtcgggttt tcaatcacac 3800

 tgaattggca ggataagaaa aataggtcag ataagtatgg gatgatagtt 3850

 gaagggaggt gaagaggctg cttctctaca gaggtgaaat tccagatgag 3900

 tcagtctctt gggaagtgtg tttagaaggg ttcaggactt tgtgagttag 3950

 catgacccta aaattctagg ggatttctgg tgggacaatg ggtggtgaat 4000

 tttgaagttt tggagaggga agtggagcag ccagcaagta agctagccag 4050

 agttttctca agagccagct ttgctcagca cactctcctg ggccccaagg 4100

 agtcccacgg aatggggaaa gtgggaaccc tggagttctt gggaatcttg 4150

 gagcctaaag agaaaccgag gtgcaaattc atttcatggt gactgaccct 4200

 tgagcttaaa cagaagcagc aaatgaaaga accggacaaa taaggaaggg 4250

 cacaagccta cccgactcta tttacagtct gtaactttcc actcttcctg 4300

 tagtcccgag gcccctgggt ccttctagct tttctctttc ccatccttgg 4350

 ggccttgtgt gatgatgggt gtggggctgc cgatgggaaa gtcgggggtt 4400

 gttaggcttt tctgcctgct cctgcttaaa cacaagaagg aatcctggat 4450

 tttgccctct ccttagctct tagtctcttt ggtaggagtt ttgttccaga 4500

 ggagctctcc cccttggatt tgaacttgct ctttttgttg ttgttgttct 4550

 ttctcttctt tttcttacct cccactaaag gggttccaaa ttatcctggt 4600

 ctttttctac cttgttgtgt ttctatctcg tctttacttc catctgtttg 4650

 tttttttctc catcagtggg ggccgagttg ttcccccagc ctgccaaatt 4700

 ttgatccttc ccctcttttg gccaaatcct agggggaaga aatcctagta 4750

 tgccaaaaat atatgctaag cataattaaa ctccatgcgg gtccataaca 4800

 gccaagaagc ctgcaggaga aagccaaggg cagttccctc cgcagaacac 4850

 cccatgcgtg ctgagaggcg agctccttga agaaggggct gttcttccag 4900

 gaggccttat tttgaactgc ctcaggaccc cactggagag cacagcatgc 4950

 cttactactg ggtcatcctt ggtctatgtg ctctgtactg gaggctctgt 5000

 tctgcctctt atcagccagg tcaggggcac acatggctta agtgacaaag 5050

 ccagaggaga agacaaccct gacagcatca cgctgcatcc cattgctagc 5100

 aggattggca actcttcaga cggagctgcg cttccctgca gtctagcacc 5150

 tctagggcct ctccagactg tgccctggga gctctgggac tgaaaggtta 5200

 agaacataag gcaggatcag atgactctct ccaagagggc aggggaattt 5250

 tctctccatg ggccacaggg gacagggctg ggagaagaaa tagacttgca 5300

 ccttatgtca tgtaaataat tgattttcta gttcaagaag ataatattgg 5350

 tagtgtggga attggaggta ggaaggggag gaagtctgag taagccagtt 5400

 ggcttctaag ccaaaaggat tcctctttgt ttatctctga gacagtccaa 5450

 ccttgagaat agctttaaaa gggaaattaa tgctgagatg ataaagtccc 5500

 cttaagccaa caaaccctct gtagctatag aatgagtgca ggtttctatt 5550

 ggtgtggact cagagcaatt tacaagagct gttcatgcag ccatccattt 5600

 gtgcaaaata gggtaagaag attcaagagg atatttatta cttcctcata 5650

 ccacatggct tttgatgatt ctggattcta aacaacccag aatggtcatt 5700

 tcaggcacaa cgatactaca ttcgtgtgtg tctgctttta aacttggctg 5750

 ggctatcaga ccctattctc ggctcaggtt ttgagaagcc atcagcaaat 5800

 gtgtacgtgc atgctgtagc tgcagcctgc atcccttcgc ctgcagccta 5850

 ctttggggaa ataaagtgcc ttactgactg tagccattac agtatccaat 5900

 gtcttttgac aggtgcctgt ccttgaaaaa caaagtttct atttttattt 5950

 ttaattggtt tagttcttaa ctgctggcca actcttacat ccccagcaaa 6000

 tcatcgggcc attggatttt ttccattatg ttcatcaccc ttatatcatg 6050

 tacctcagat ctctctctct ctcctctctc tcagttatat agtttcttgt 6100

 cttggacttt ttttttcttt tctttttctt tttttttttg ctttaaaaca 6150

 agtgtgatgc catatcaagt ccatgttatt ctctcacagt gtactctata 6200

 agaggtgtgg gtgtctgttt ggtcaggatg ttagaaagtg ctgataagta 6250

 gcatgatcag tgtatgcgaa aaggttttta ggaagtatgg caaaaatgtt 6300

 gtattggcta tgatggtgac atgatatagt cagctgcctt ttaagaggtc 6350

 ttatctgttc agtgttaagt gatttaaaaa aataataacc tgttttctga 6400

 ctagtttaaa gatggatttg aaaatggttt tgaatgcaat taggttatgc 6450

 tatttggaca ataaactcac cttgacct 6478

<210> 4846
<211> 289
<212> PRT
<213> Homo sapien

<400> 4846
 Met Glu Leu Leu Cys His Glu Val Asp Pro Val Arg Arg Ala Val
   1               5                  10                  15

 Arg Asp Arg Asn Leu Leu Arg Asp Asp Arg Val Leu Gln Asn Leu
                  20                  25                  30

 Leu Thr Ile Glu Glu Arg Tyr Leu Pro Gln Cys Ser Tyr Phe Lys
                  35                  40                  45

 Cys Val Gln Lys Asp Ile Gln Pro Tyr Met Arg Arg Met Val Ala
                  50                  55                  60

 Thr Trp Met Leu Glu Val Cys Glu Glu Gln Lys Cys Glu Glu Glu
                  65                  70                  75

 Val Phe Pro Leu Ala Met Asn Tyr Leu Asp Arg Phe Leu Ala Gly
                  80                  85                  90

 Val Pro Thr Pro Lys Ser His Leu Gln Leu Leu Gly Ala Val Cys
                  95                 100                 105

 Met Phe Leu Ala Ser Lys Leu Lys Glu Thr Ser Pro Leu Thr Ala
                 110                 115                 120

 Glu Lys Leu Cys Ile Tyr Thr Asp Asn Ser Ile Lys Pro Gln Glu
                 125                 130                 135

 Leu Leu Glu Trp Glu Leu Val Val Leu Gly Lys Leu Lys Trp Asn
                 140                 145                 150

 Leu Ala Ala Val Thr Pro His Asp Phe Ile Glu His Ile Leu Arg
                 155                 160                 165

 Lys Leu Pro Gln Gln Arg Glu Lys Leu Ser Leu Ile Arg Lys His
                 170                 175                 180

 Ala Gln Thr Phe Ile Ala Leu Cys Ala Thr Asp Phe Lys Phe Ala
                 185                 190                 195

 Met Tyr Pro Pro Ser Met Ile Ala Thr Gly Ser Val Gly Ala Ala
                 200                 205                 210

 Ile Cys Gly Leu Gln Gln Asp Glu Glu Val Ser Ser Leu Thr Cys
                 215                 220                 225

 Asp Ala Leu Thr Glu Leu Leu Ala Lys Ile Thr Asn Thr Asp Val
                 230                 235                 240

 Asp Cys Leu Lys Ala Cys Gln Glu Gln Ile Glu Ala Val Leu Leu
                 245                 250                 255

 Asn Ser Leu Gln Gln Tyr Arg Gln Asp Gln Arg Asp Gly Ser Lys
                 260                 265                 270

 Ser Glu Asp Glu Leu Asp Gln Ala Ser Thr Pro Thr Asp Val Arg
                 275                 280                 285

 Asp Ile Asp Leu


<210> 4847
<211> 3768
<212> DNA
<213> Homo sapien

<400> 4847
 gagaggctgg cggcagtggt ggctctcccg gctgggttgt cagtcagtga 50

 gaggaggggg aagatggctc accgggaccc gttctgctag gaagaagggg 100

 agcaggtggt gctgctactc gggaggaagc agagcagcct ccgtcgctgt 150

 cgctgagagc ctcacgagtc gaggtcctgc aggtggagct ccggcagccg 200

 ccctggttga aggtttagaa cagatgtgga aaaatgttta cttcagagaa 250

 aggggttgtg gaggaatggt tgtcagagtt taagacatta ccagaaacat 300

 ctttaccaaa ttatgccaca aatttgaaag acaagagttc tttagtttca 350

 tctctctata aagttatcca ggagccacaa agtgagttgc tagaacctgt 400

 ctgtcaccag ctctttgaat tctatcgcag tggagaggag cagttgcttc 450

 aatttacgct gcaatttctc ccagaactaa tttggtgcta ccttgcagtc 500

 tcagccagca gaaatgtgca tagcagtgga tgcattgaag ctcttcttct 550

 aggggtttac aatttggaaa tagttgacaa acagggacat accaaagtat 600

 tgagttttac gattccatct ttatccaaac catctgtata ccatgaacct 650

 tccagcattg ggtccatggc tctgactgag agtgcactat cccagcatgg 700

 tttgtcaaaa gtggtataca gtggacctca tcctcaaagg gagatgctga 750

 cagcacagaa tcggtttgaa gtgttgacat tccttttgtt gtgttacaat 800

 gctgccttaa cttacatgcc cagtgtttct cttcagtcac tgtgtcaaat 850

 ttgttcaaga atctgtgttt gtggatatcc tcgacaacat gtaagaaaat 900

 ataaaggtat aagtagcagg ataccagttt cttcaggatt catggtgcaa 950

 atgttaacag ggatttattt tgccttttat aatggagaat gggatctagc 1000

 tcaaaaagca ctggatgata ttatatacag agcccagcta gaattatatc 1050

 cagagccatt gctggttgct aatgcaataa aggcttcatt gcctcatggt 1100

 cccatgaaat ctaataagga aggtacaagg tgtattcaag ttgaaatcac 1150

 accaacttcc tctcgaatat caagaaatgc agtaaccagc atgtcaataa 1200

 ggggtcatag gtggaaaaga catggaaata cagaattaac aggtcaagaa 1250

 gaactgatgg agatatctga agttgacgag ggattttatt ccagggctgc 1300

 gtctagtacc agccagtcgg gtttatcaaa cagtagtcac aattgtagta 1350

 acaagccaag tataggaaag aaccacagac ggtcaggagg aagcaaaact 1400

 ggaggaaaag aaaaagaaac tacaggggaa tcttgcaaag atcactttgc 1450

 tcgaaaacaa actcagagag cccaaagtga gaatcttgag cttctctctt 1500

 tgaagagact tactttaaca accagccaat ccctacctaa gcctagtagc 1550

 catggtttgg ctaagaccgc agcgactgta tttagtaaat cctttgaaca 1600

 agtcagtggt gtcacagtcc cacataaccc gtcatctgct gttggttgtg 1650

 gggctgggac agatgccaat aggttttccg cttgtagtct ccaagaagaa 1700

 aagcttattt acgtttcaga aagaactgaa cttccaatga agcatcaatc 1750

 aggtcagcag agacctccta gtattagcat tactctgtcc acagattaat 1800

 tagtaacata tttttctccc ataacctagt gaacctggaa atacaacttt 1850

 gcttctttat gaaagtaccc tgggtctttc atccgtattc ctgacaggag 1900

 ccctgatgtc ttaaattctg aaggctcccc tgactttatg aagggaagat 1950

 tgtctaggtt gcagtaagtt gaaatatggt tttgttattt cttgattaag 2000

 attttttccc cttggtttga gtcttttttt tccctcctct tatttgttat 2050

 tgttgcccta agattgtcag tgacaataaa ttttgacagg ttgtctaatc 2100

 aagttggtta tgtctcatgt gaggttgtaa ggtggttttt cttgttttgg 2150

 tttggtttgg ttttttaata gctcctattt tgatggctgt gtgtttggcc 2200

 ttcagagtca aagggagtct gcatgtatgg gaactgtttt atagagaatg 2250

 gggcagaggc acaactccag gaattctcta gctcctggtc aggaagccaa 2300

 tctgaaaaca ggcatgtgga aacacaaaaa tgatgtgtat gaaaagcacc 2350

 tgatgaaaat atttgtaagc agatcatctt tatgattaga acaatttgct 2400

 caaagccctg gaaaatgcct ggtaacccag tgcctagaat attatatgat 2450

 tccaggggat ggctagaggc atttctgttg ttatctctga aacattttta 2500

 tatcaaaaat cagattgctg gtaggtgtgt tgttttgaag tgttttatct 2550

 ggatttagca tgtgaagatc cctttcaatt attaaggtat aataggctgt 2600

 aaagctgatt taccctactg ctggactttg gaaatcctag ttagtttgga 2650

 ctcctataat tcagagcata cgtcattgga agacttcctg gaaatcagtg 2700

 taaatcttgc aacatagctc tcaagatacc actgtataat atgtaattgt 2750

 ttgtctgcaa atgcattttt catctataaa atgtcatgaa agaaaataaa 2800

 ggtagtgaaa tatggacaaa ggacatttat atattaacta aagttgttta 2850

 tgtttgtgtt cttaaattta aaacacgaag aaaaagaaat gtctttcttg 2900

 ttagtgaaca ggcctgtttt aaatatctta gtatgatatc aaaagaataa 2950

 tcaatttagt tacctcccaa ctaaaaagta aaaatgaaaa agacgacatg 3000

 gcagaagttg aaacaaactt gtatgtatct gtatgtgacc tctagatgga 3050

 aataaaagtt tgatgtttgc tagccgtggt ccttttggct atggttgcgg 3100

 ttcccctgta aagcaaatgt acttaagtca tcattcagag tgagagagag 3150

 aaagcacggc tgaggctgag tcagttgacc gttgaggaag acctaaggag 3200

 ctgtccagtt cttggctctt tttcactgtg actgcacagc ggtttccttc 3250

 ttcatagtcc cttgctgtag tcaccaagag agcatgctag tgttttcctc 3300

 ttgttcctgc ttatgcagag ctcagatata tgaaaaattt gtatgctttg 3350

 aaggctgcca aagcatttat actctggaca tagttttaac tgcaactgct 3400

 ttggctacca gtttaaaccg agttcttcaa aaagcatgaa ctcgttttca 3450

 ttcattagcc ctgtttacaa tgtggatttt gacataaatg aatttgattt 3500

 tcttttagct ccagtaacag aatggaataa gatctattgc cataaattgt 3550

 agttaagaac tgtaaggcaa tcgggcagtg aaacttgata ttgtattaac 3600

 ttaataggaa ccctgtgtac aatttaaaat atttgtaaaa tatcactgtg 3650

 aatttacaga tgtctttttg tcattcttta acaatgaatt tcccctgtgc 3700

 atagttatta atagtattgg tattattaaa aactaatttg gcattttaaa 3750

 aaaaaaaaaa aaaaaaaa 3768

<210> 4848
<211> 521
<212> PRT
<213> Homo sapien

<400> 4848
 Met Phe Thr Ser Glu Lys Gly Val Val Glu Glu Trp Leu Ser Glu
   1               5                  10                  15

 Phe Lys Thr Leu Pro Glu Thr Ser Leu Pro Asn Tyr Ala Thr Asn
                  20                  25                  30

 Leu Lys Asp Lys Ser Ser Leu Val Ser Ser Leu Tyr Lys Val Ile
                  35                  40                  45

 Gln Glu Pro Gln Ser Glu Leu Leu Glu Pro Val Cys His Gln Leu
                  50                  55                  60

 Phe Glu Phe Tyr Arg Ser Gly Glu Glu Gln Leu Leu Gln Phe Thr
                  65                  70                  75

 Leu Gln Phe Leu Pro Glu Leu Ile Trp Cys Tyr Leu Ala Val Ser
                  80                  85                  90

 Ala Ser Arg Asn Val His Ser Ser Gly Cys Ile Glu Ala Leu Leu
                  95                 100                 105

 Leu Gly Val Tyr Asn Leu Glu Ile Val Asp Lys Gln Gly His Thr
                 110                 115                 120

 Lys Val Leu Ser Phe Thr Ile Pro Ser Leu Ser Lys Pro Ser Val
                 125                 130                 135

 Tyr His Glu Pro Ser Ser Ile Gly Ser Met Ala Leu Thr Glu Ser
                 140                 145                 150

 Ala Leu Ser Gln His Gly Leu Ser Lys Val Val Tyr Ser Gly Pro
                 155                 160                 165

 His Pro Gln Arg Glu Met Leu Thr Ala Gln Asn Arg Phe Glu Val
                 170                 175                 180

 Leu Thr Phe Leu Leu Leu Cys Tyr Asn Ala Ala Leu Thr Tyr Met
                 185                 190                 195

 Pro Ser Val Ser Leu Gln Ser Leu Cys Gln Ile Cys Ser Arg Ile
                 200                 205                 210

 Cys Val Cys Gly Tyr Pro Arg Gln His Val Arg Lys Tyr Lys Gly
                 215                 220                 225

 Ile Ser Ser Arg Ile Pro Val Ser Ser Gly Phe Met Val Gln Met
                 230                 235                 240

 Leu Thr Gly Ile Tyr Phe Ala Phe Tyr Asn Gly Glu Trp Asp Leu
                 245                 250                 255

 Ala Gln Lys Ala Leu Asp Asp Ile Ile Tyr Arg Ala Gln Leu Glu
                 260                 265                 270

 Leu Tyr Pro Glu Pro Leu Leu Val Ala Asn Ala Ile Lys Ala Ser
                 275                 280                 285

 Leu Pro His Gly Pro Met Lys Ser Asn Lys Glu Gly Thr Arg Cys
                 290                 295                 300

 Ile Gln Val Glu Ile Thr Pro Thr Ser Ser Arg Ile Ser Arg Asn
                 305                 310                 315

 Ala Val Thr Ser Met Ser Ile Arg Gly His Arg Trp Lys Arg His
                 320                 325                 330

 Gly Asn Thr Glu Leu Thr Gly Gln Glu Glu Leu Met Glu Ile Ser
                 335                 340                 345

 Glu Val Asp Glu Gly Phe Tyr Ser Arg Ala Ala Ser Ser Thr Ser
                 350                 355                 360

 Gln Ser Gly Leu Ser Asn Ser Ser His Asn Cys Ser Asn Lys Pro
                 365                 370                 375

 Ser Ile Gly Lys Asn His Arg Arg Ser Gly Gly Ser Lys Thr Gly
                 380                 385                 390

 Gly Lys Glu Lys Glu Thr Thr Gly Glu Ser Cys Lys Asp His Phe
                 395                 400                 405

 Ala Arg Lys Gln Thr Gln Arg Ala Gln Ser Glu Asn Leu Glu Leu
                 410                 415                 420

 Leu Ser Leu Lys Arg Leu Thr Leu Thr Thr Ser Gln Ser Leu Pro
                 425                 430                 435

 Lys Pro Ser Ser His Gly Leu Ala Lys Thr Ala Ala Thr Val Phe
                 440                 445                 450

 Ser Lys Ser Phe Glu Gln Val Ser Gly Val Thr Val Pro His Asn
                 455                 460                 465

 Pro Ser Ser Ala Val Gly Cys Gly Ala Gly Thr Asp Ala Asn Arg
                 470                 475                 480

 Phe Ser Ala Cys Ser Leu Gln Glu Glu Lys Leu Ile Tyr Val Ser
                 485                 490                 495

 Glu Arg Thr Glu Leu Pro Met Lys His Gln Ser Gly Gln Gln Arg
                 500                 505                 510

 Pro Pro Ser Ile Ser Ile Thr Leu Ser Thr Asp
                 515                 520

<210> 4849
<211> 348
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 34-35
<223> Unknown base

<400> 4849
 gagggatgat ttcagagcac tttgagattt accnnccttt agaatccctt 50

 acatggtcga tataaaaggg aagcaattct gaatcctatt actagcctgc 100

 accatgatcc caaaaaccta tacaggaagt aggagcatca caacaaccaa 150

 aatctagcca gaatggggaa aatagattag atatcttatt ttgttcccaa 200

 gatccactgc atagtcccag agctaaagtg agagccttta ttcctggtta 250

 cattcacttc cctatgaatc tctccaaaaa acctacaata gtgtgacagc 300

 tagtagctat gcacagtcta tcagcaatgg ctcagtgaac ctctattc 348

<210> 4850
<211> 2
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 34-35
<223> Unknown amino acid

<400> 4850
 Glu Gly
   1

<210> 4851
<211> 2881
<212> DNA
<213> Homo sapien

<400> 4851
 acagaagtgc tagaagccag tgctcgtgaa ctaaggagaa aaagaacaga 50

 caagggaaca gcctggacat ggcatcagag atccacatga caggcccaat 100

 gtgcctcatt gagaacacta atgggcgact gatggcgaat ccagaagctc 150

 tgaagatcct ttctgccatt acacagccta tggtggtggt ggcaattgtg 200

 ggcctctacc gcacaggcaa atcctacctg atgaacaagc tggctggaaa 250

 gaaaaagggc ttctctctgg gctccacggt gcagtctcac actaaaggaa 300

 tctggatgtg gtgtgtgccc caccccaaga agccaggcca catcctagtt 350

 ctgctggaca ccgagggtct gggagatgta gagaagggtg acaaccagaa 400

 tgactcctgg atcttcgccc tggccgtcct cctgagcagc accttcgtgt 450

 acaatagcat aggaaccatc aaccagcagg ctatggacca actgtactat 500

 gtgacagagc tgacacatag aatccgatca aaatcctcac ctgatgagaa 550

 tgagaatgag gttgaggatt cagctgactt tgtgagcttc ttcccagact 600

 ttgtgtggac actgagagat ttctccctgg acttggaagc agatggacaa 650

 cccctcacac cagatgagta cctgacatac tccctgaagc tgaagaaagg 700

 taccagtcaa aaagatgaaa cttttaacct gcccagactc tgtatccgga 750

 aattcttccc aaagaaaaaa tgctttgtct ttgatcggcc cgttcaccgc 800

 aggaagcttg cccagctcga gaaactacaa gatgaagagc tggaccccga 850

 atttgtgcaa caagtagcag acttctgttc ctacatcttt agtaattcca 900

 aaactaaaac tctttcagga ggcatccagg tcaacgggcc tcgtctagag 950

 agcctggtgc tgacctacgt caatgccatc agcagtgggg atctgccgtg 1000

 catggagaac gcagtcctgg ccttggccca gatagagaac tcagctgcag 1050

 tgcaaaaggc tattgcccac tatgaacagc agatgggcca gaaggtgcag 1100

 ctgcccacag aaagcctcca ggagctgctg gacctgcaca gggacagtga 1150

 gagagaggcc attgaagtct tcatcaggag ttccttcaaa gatgtggacc 1200

 atctatttca aaaggagtta gcggcccagc tagaaaaaaa gcgggatgac 1250

 ttttgtaaac agaatcagga agcatcatca gatcgttgct caggtttact 1300

 tcaggtcatt ttcagtcctc tagaagaaga agtgaaggcg ggaatttatt 1350

 cgaaaccagg gggctatcgt ctctttgttc agaagctaca agacctgaag 1400

 aaaaagtact atgaggaacc gaggaagggg atacaggctg aagagattct 1450

 gcagacatac ttgaaatcca aggagtctat gactgatgca attctccaga 1500

 cagaccagac tctcacagaa aaagaaaagg agattgaagt ggaacgtgtg 1550

 aaagctgagt ctgcacaggc ttcagcaaaa atgttgcagg aaatgcaaag 1600

 aaagaatgag cagatgatgg aacagaagga gaggagttat caggaacact 1650

 tgaaacaact gactgagaag atggagaacg acagggtcca gttgctgaaa 1700

 gagcaagaga ggaccctcgc tcttaaactt caggaacagg agcaactact 1750

 aaaagaggga tttcaaaaag aaagcagaat aatgaaaaat gagatacagg 1800

 atctccagac gaaaatgaga cgacgaaagg catgtaccat aagctaaaga 1850

 ccagagcctt cctgtcaccc ctaaccaagg cataattgaa acaattttag 1900

 aatttggaac aagcgtcact acatttgata ataattagat cttgcatcat 1950

 aacaccaaaa gtttataaag gcatgtggta caatgatcaa aatcatgttt 2000

 tttcttaaaa aaaaaaaaaa gactgtaaat tgtgcaacaa agatgcattt 2050

 acctctgtat caactcagga aatctcataa gctggtacca ctcaggagaa 2100

 gtttattctt ccagatgacc agcagtagac aaatggatac tgagcagagt 2150

 cttaggtaaa agtcttggga aatatttggg cattggtctg gccaagtcta 2200

 caatgtccca atatcaagga caaccaccct agcttcttag tgaagacaat 2250

 gtacagttat ccattagatc aagactacac ggtctatgag caataatgtg 2300

 atttctggac attgcccatg tataatcctc actgatgatt tcaagctaaa 2350

 gcaaaccacc ttatacagag atctagaatc tctttatgtt ctccagagga 2400

 aggtggaaga aaccatgggc aggagtagga attgagtgat aaacaattgg 2450

 gctaatgaag aaaacttctc ttattgttca gttcatccag attataactt 2500

 caatgggaca ctttagacca ttagacaatt gacactggat taaacaaatt 2550

 cacataatgc caaatacaca atgtatttat agcaacgtat aatttgcaaa 2600

 gatggacttt aaaagatgct gtgtaactaa actgaaataa ttcaattact 2650

 tattatttag aatgttaaag cttatgatag tcttttctaa ttcttaacac 2700

 tcatacttga aatctttccg agtttcccca gaagagaata tgggattttt 2750

 tttgacattt ttgacccatt taataatgct cttgtgttta cctagtatat 2800

 gtagactttg tcttatgtgt caaaagtcct aggaaagtgg ttgatgtttc 2850

 ttatagcaat taaaaattat ttttgaactg a 2881

<210> 4852
<211> 592
<212> PRT
<213> Homo sapien

<400> 4852
 Met Ala Ser Glu Ile His Met Thr Gly Pro Met Cys Leu Ile Glu
   1               5                  10                  15

 Asn Thr Asn Gly Arg Leu Met Ala Asn Pro Glu Ala Leu Lys Ile
                  20                  25                  30

 Leu Ser Ala Ile Thr Gln Pro Met Val Val Val Ala Ile Val Gly
                  35                  40                  45

 Leu Tyr Arg Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly
                  50                  55                  60

 Lys Lys Lys Gly Phe Ser Leu Gly Ser Thr Val Gln Ser His Thr
                  65                  70                  75

 Lys Gly Ile Trp Met Trp Cys Val Pro His Pro Lys Lys Pro Gly
                  80                  85                  90

 His Ile Leu Val Leu Leu Asp Thr Glu Gly Leu Gly Asp Val Glu
                  95                 100                 105

 Lys Gly Asp Asn Gln Asn Asp Ser Trp Ile Phe Ala Leu Ala Val
                 110                 115                 120

 Leu Leu Ser Ser Thr Phe Val Tyr Asn Ser Ile Gly Thr Ile Asn
                 125                 130                 135

 Gln Gln Ala Met Asp Gln Leu Tyr Tyr Val Thr Glu Leu Thr His
                 140                 145                 150

 Arg Ile Arg Ser Lys Ser Ser Pro Asp Glu Asn Glu Asn Glu Val
                 155                 160                 165

 Glu Asp Ser Ala Asp Phe Val Ser Phe Phe Pro Asp Phe Val Trp
                 170                 175                 180

 Thr Leu Arg Asp Phe Ser Leu Asp Leu Glu Ala Asp Gly Gln Pro
                 185                 190                 195

 Leu Thr Pro Asp Glu Tyr Leu Thr Tyr Ser Leu Lys Leu Lys Lys
                 200                 205                 210

 Gly Thr Ser Gln Lys Asp Glu Thr Phe Asn Leu Pro Arg Leu Cys
                 215                 220                 225

 Ile Arg Lys Phe Phe Pro Lys Lys Lys Cys Phe Val Phe Asp Arg
                 230                 235                 240

 Pro Val His Arg Arg Lys Leu Ala Gln Leu Glu Lys Leu Gln Asp
                 245                 250                 255

 Glu Glu Leu Asp Pro Glu Phe Val Gln Gln Val Ala Asp Phe Cys
                 260                 265                 270

 Ser Tyr Ile Phe Ser Asn Ser Lys Thr Lys Thr Leu Ser Gly Gly
                 275                 280                 285

 Ile Gln Val Asn Gly Pro Arg Leu Glu Ser Leu Val Leu Thr Tyr
                 290                 295                 300

 Val Asn Ala Ile Ser Ser Gly Asp Leu Pro Cys Met Glu Asn Ala
                 305                 310                 315

 Val Leu Ala Leu Ala Gln Ile Glu Asn Ser Ala Ala Val Gln Lys
                 320                 325                 330

 Ala Ile Ala His Tyr Glu Gln Gln Met Gly Gln Lys Val Gln Leu
                 335                 340                 345

 Pro Thr Glu Ser Leu Gln Glu Leu Leu Asp Leu His Arg Asp Ser
                 350                 355                 360

 Glu Arg Glu Ala Ile Glu Val Phe Ile Arg Ser Ser Phe Lys Asp
                 365                 370                 375

 Val Asp His Leu Phe Gln Lys Glu Leu Ala Ala Gln Leu Glu Lys
                 380                 385                 390

 Lys Arg Asp Asp Phe Cys Lys Gln Asn Gln Glu Ala Ser Ser Asp
                 395                 400                 405

 Arg Cys Ser Gly Leu Leu Gln Val Ile Phe Ser Pro Leu Glu Glu
                 410                 415                 420

 Glu Val Lys Ala Gly Ile Tyr Ser Lys Pro Gly Gly Tyr Arg Leu
                 425                 430                 435

 Phe Val Gln Lys Leu Gln Asp Leu Lys Lys Lys Tyr Tyr Glu Glu
                 440                 445                 450

 Pro Arg Lys Gly Ile Gln Ala Glu Glu Ile Leu Gln Thr Tyr Leu
                 455                 460                 465

 Lys Ser Lys Glu Ser Met Thr Asp Ala Ile Leu Gln Thr Asp Gln
                 470                 475                 480

 Thr Leu Thr Glu Lys Glu Lys Glu Ile Glu Val Glu Arg Val Lys
                 485                 490                 495

 Ala Glu Ser Ala Gln Ala Ser Ala Lys Met Leu Gln Glu Met Gln
                 500                 505                 510

 Arg Lys Asn Glu Gln Met Met Glu Gln Lys Glu Arg Ser Tyr Gln
                 515                 520                 525

 Glu His Leu Lys Gln Leu Thr Glu Lys Met Glu Asn Asp Arg Val
                 530                 535                 540

 Gln Leu Leu Lys Glu Gln Glu Arg Thr Leu Ala Leu Lys Leu Gln
                 545                 550                 555

 Glu Gln Glu Gln Leu Leu Lys Glu Gly Phe Gln Lys Glu Ser Arg
                 560                 565                 570

 Ile Met Lys Asn Glu Ile Gln Asp Leu Gln Thr Lys Met Arg Arg
                 575                 580                 585

 Arg Lys Ala Cys Thr Ile Ser
                 590

<210> 4853
<211> 1537
<212> DNA
<213> Homo sapien

<400> 4853
 gaggaagaag aatctgtata tctgtatata ttggctagca aatgtgccct 50

 gctctctccc ctcttaaaaa tagcagcaac ccatctttgc aaagaagctt 100

 gcctatagag caggcactct gtgaatggac tgtgctttta cgaccctaca 150

 gggtatcaag atactgtgca gctcgccaac aaggattaat tgcaaggact 200

 ggtagatcga atttactgaa gacttggagc ttgcttctga gaacaaacgc 250

 aaaaggacag taaactgtgg accttgaagt tagcagcgtg ggcttcctct 300

 aatattacac cgtaaaaggc attgatcacc ataagaagga acatttgtga 350

 aggtactcca gtgccagaaa gaggcacaaa gcagacattc gtagagaaac 400

 atggatgaaa caggaaatct gacagtatct tctgccacat gccatgacac 450

 tattgatgac ttccgcaatc aagtgtattc caccttgtac tctatgatct 500

 ctgttgtagg cttctttggc aatggctttg tgctctatgt cctcataaaa 550

 acctatcaca agaagtcagc cttccaagta tacatgatta atttagcagt 600

 agcagatcta ctttgtgtgt gcacactgcc tctccgtgtg gtctattatg 650

 ttcacaaagg catttggctc tttggtgact tcttgtgccg cctcagcacc 700

 tatgctttgt atgtcaacct ctattgtagc atcttcttta tgacagccat 750

 gagctttttc cggtgcattg caattgtttt tccagtccag aacattaatt 800

 tggttacaca gaaaaaagcc aggtttgtgt gtgtaggtat ttggattttt 850

 gtgattttga ccagttctcc atttctaatg gccaaaccac aaaaagatga 900

 gaaaaataat accaagtgct ttgagccccc acaagacaat caaactaaaa 950

 atcatgtttt ggtcttgcat tatgtgtcat tgtttgttgg ctttatcatc 1000

 ccttttgtta ttataattgt ctgttacaca atgatcattt tgaccttact 1050

 aaaaaaatca atgaaaaaaa atctgtcaag tcataaaaag gctataggaa 1100

 tgatcatggt cgtgaccgct gcctttttag tcagtttcat gccatatcat 1150

 attcaacgta ccattcacct tcatttttta cacaatgaaa ctaaaccctg 1200

 tgattctgtc cttagaatgc agaagtccgt ggtcataacc ttgtctctgg 1250

 ctgcatccaa ttgttgcttt gaccctctcc tatatttctt ttctgggggt 1300

 aactttagga aaaggctgtc tacattcaga aagcattctt tgtccagcgt 1350

 gacttatgta cccagaaaga aggcctcttt gccagaaaaa ggagaagaaa 1400

 tatgtaaagt atagtttaaa cccatttcca gtccaaacca atgaaaatag 1450

 tttcccaaat aagtattttg tcaaatcatt tacaaaaaaa ataaaaattt 1500

 tacttaatat tttaaaaaaa aaaaaaaaaa aaaaaaa 1537

<210> 4854
<211> 337
<212> PRT
<213> Homo sapien

<400> 4854
 Met Asp Glu Thr Gly Asn Leu Thr Val Ser Ser Ala Thr Cys His
   1               5                  10                  15

 Asp Thr Ile Asp Asp Phe Arg Asn Gln Val Tyr Ser Thr Leu Tyr
                  20                  25                  30

 Ser Met Ile Ser Val Val Gly Phe Phe Gly Asn Gly Phe Val Leu
                  35                  40                  45

 Tyr Val Leu Ile Lys Thr Tyr His Lys Lys Ser Ala Phe Gln Val
                  50                  55                  60

 Tyr Met Ile Asn Leu Ala Val Ala Asp Leu Leu Cys Val Cys Thr
                  65                  70                  75

 Leu Pro Leu Arg Val Val Tyr Tyr Val His Lys Gly Ile Trp Leu
                  80                  85                  90

 Phe Gly Asp Phe Leu Cys Arg Leu Ser Thr Tyr Ala Leu Tyr Val
                  95                 100                 105

 Asn Leu Tyr Cys Ser Ile Phe Phe Met Thr Ala Met Ser Phe Phe
                 110                 115                 120

 Arg Cys Ile Ala Ile Val Phe Pro Val Gln Asn Ile Asn Leu Val
                 125                 130                 135

 Thr Gln Lys Lys Ala Arg Phe Val Cys Val Gly Ile Trp Ile Phe
                 140                 145                 150

 Val Ile Leu Thr Ser Ser Pro Phe Leu Met Ala Lys Pro Gln Lys
                 155                 160                 165

 Asp Glu Lys Asn Asn Thr Lys Cys Phe Glu Pro Pro Gln Asp Asn
                 170                 175                 180

 Gln Thr Lys Asn His Val Leu Val Leu His Tyr Val Ser Leu Phe
                 185                 190                 195

 Val Gly Phe Ile Ile Pro Phe Val Ile Ile Ile Val Cys Tyr Thr
                 200                 205                 210

 Met Ile Ile Leu Thr Leu Leu Lys Lys Ser Met Lys Lys Asn Leu
                 215                 220                 225

 Ser Ser His Lys Lys Ala Ile Gly Met Ile Met Val Val Thr Ala
                 230                 235                 240

 Ala Phe Leu Val Ser Phe Met Pro Tyr His Ile Gln Arg Thr Ile
                 245                 250                 255

 His Leu His Phe Leu His Asn Glu Thr Lys Pro Cys Asp Ser Val
                 260                 265                 270

 Leu Arg Met Gln Lys Ser Val Val Ile Thr Leu Ser Leu Ala Ala
                 275                 280                 285

 Ser Asn Cys Cys Phe Asp Pro Leu Leu Tyr Phe Phe Ser Gly Gly
                 290                 295                 300

 Asn Phe Arg Lys Arg Leu Ser Thr Phe Arg Lys His Ser Leu Ser
                 305                 310                 315

 Ser Val Thr Tyr Val Pro Arg Lys Lys Ala Ser Leu Pro Glu Lys
                 320                 325                 330

 Gly Glu Glu Ile Cys Lys Val
                 335

<210> 4855
<211> 1535
<212> DNA
<213> Homo sapien

<400> 4855
 gcgcgttcgg gagcttcggc cctgcgtagg aggcgggtgc aggtgtgggt 50

 gctgagccgc ccgccgcctg gagggggaga cagcttcagg acacgcaggc 100

 cgcagcgagg gcccgggccc gggggatccc aggccatgga tgctccccac 150

 tccaaagcag ccctggacag cattaacgag ctgcccgaga acatcctgct 200

 ggagctgttc acgcacgtgc ccgcccgcca gctgctgctg aactgccgcc 250

 tggtctgcag cctctggcgg gacctcatcg acctcatgac cctctggaaa 300

 cgcaagtgcc tgcgagaggg cttcatcacc aaggactggg accagcccgt 350

 ggccgactgg aaaatcttct acttcctacg gagcctgcat aggaacctcc 400

 tgcgcaaccc gtgtgctgaa gaggatatgt ttgcatggca aattgatttc 450

 aatggtgggg accgctggaa ggtggagagc ctccctggag cccacgggac 500

 agattttcct gaccccaaag tcaagaagta ttttgtcaca tcctacgaaa 550

 tgtgcctcaa gtcccagctg gtggaccttg tagccgaggg ctactgggag 600

 gagctactag acacattccg gccggacatc gtggttaagg actggtttgc 650

 tgccagagcc gactgtggct gcacctacca actcaaagtg cagctggcct 700

 cggctgacta cttcgtgttg gcctccttcg agcccccacc tgtgaccatc 750

 caacagtgga acaatgccac atggacagag gtctcctaca ccttctcaga 800

 ctacccccgg ggtgtccgct acatcctctt ccagcatggg ggcagggaca 850

 cccagtactg ggcaggctgg tatgggcccc gagtcaccaa cagcagcatt 900

 gtcgtcagcc ccaagatgac caggaaccag gcctcctccg aggctcagcc 950

 tgggcagaag catggacagg aggaggctgc ccaatcgccc taccgagctg 1000

 ttgtccagat tttctgacag ctgtccatcc tgtgtctggg tcagccagag 1050

 gttcctccag gcaggagctg agcatggggt gggcagtgag gtccctgtac 1100

 cagcgactcc tgccccggtt caaccctacc agcttgtggt aacttactgt 1150

 cacatagctc tgacgttttg ttgtaataaa tgttttcagg ccgggcactg 1200

 tggctcacgc ctgtaatccc agcactttgg gagaccgagg caggtggatc 1250

 acgaggtcag gagacagaga ccatcctggc caacacggtg aaaccctgtc 1300

 tctactaaaa atacaaaaaa ttagccgggc gtggtggcgg gcgcctgtag 1350

 tcccagctac tcgggaggct gatgcagaag aatggcgtga acccggaagg 1400

 cagagcttgc agtgagccga gatcacgcca ctgcactcca gcctgggtga 1450

 cagagcgaga ctctggctca taaaataata ataataataa ataaataaaa 1500

 aataaatggt tttcagtaaa aaaaaaaaaa aaaaa 1535

<210> 4856
<211> 293
<212> PRT
<213> Homo sapien

<400> 4856
 Met Asp Ala Pro His Ser Lys Ala Ala Leu Asp Ser Ile Asn Glu
   1               5                  10                  15

 Leu Pro Glu Asn Ile Leu Leu Glu Leu Phe Thr His Val Pro Ala
                  20                  25                  30

 Arg Gln Leu Leu Leu Asn Cys Arg Leu Val Cys Ser Leu Trp Arg
                  35                  40                  45

 Asp Leu Ile Asp Leu Met Thr Leu Trp Lys Arg Lys Cys Leu Arg
                  50                  55                  60

 Glu Gly Phe Ile Thr Lys Asp Trp Asp Gln Pro Val Ala Asp Trp
                  65                  70                  75

 Lys Ile Phe Tyr Phe Leu Arg Ser Leu His Arg Asn Leu Leu Arg
                  80                  85                  90

 Asn Pro Cys Ala Glu Glu Asp Met Phe Ala Trp Gln Ile Asp Phe
                  95                 100                 105

 Asn Gly Gly Asp Arg Trp Lys Val Glu Ser Leu Pro Gly Ala His
                 110                 115                 120

 Gly Thr Asp Phe Pro Asp Pro Lys Val Lys Lys Tyr Phe Val Thr
                 125                 130                 135

 Ser Tyr Glu Met Cys Leu Lys Ser Gln Leu Val Asp Leu Val Ala
                 140                 145                 150

 Glu Gly Tyr Trp Glu Glu Leu Leu Asp Thr Phe Arg Pro Asp Ile
                 155                 160                 165

 Val Val Lys Asp Trp Phe Ala Ala Arg Ala Asp Cys Gly Cys Thr
                 170                 175                 180

 Tyr Gln Leu Lys Val Gln Leu Ala Ser Ala Asp Tyr Phe Val Leu
                 185                 190                 195

 Ala Ser Phe Glu Pro Pro Pro Val Thr Ile Gln Gln Trp Asn Asn
                 200                 205                 210

 Ala Thr Trp Thr Glu Val Ser Tyr Thr Phe Ser Asp Tyr Pro Arg
                 215                 220                 225

 Gly Val Arg Tyr Ile Leu Phe Gln His Gly Gly Arg Asp Thr Gln
                 230                 235                 240

 Tyr Trp Ala Gly Trp Tyr Gly Pro Arg Val Thr Asn Ser Ser Ile
                 245                 250                 255

 Val Val Ser Pro Lys Met Thr Arg Asn Gln Ala Ser Ser Glu Ala
                 260                 265                 270

 Gln Pro Gly Gln Lys His Gly Gln Glu Glu Ala Ala Gln Ser Pro
                 275                 280                 285

 Tyr Arg Ala Val Val Gln Ile Phe
                 290

<210> 4857
<211> 2756
<212> DNA
<213> Homo sapien

<400> 4857
 atgcagttag gggagcagct cttggtgagc tcagtgaacc tgcctggcgc 50

 gcacttctac ccgctggaga gtgcgcgagg cggcagcggc gggagcgctg 100

 gccacctccc cagcgcggcc ccctctcctc agaagttgga cttagacaaa 150

 gcgtccaaga agttttccgg cagtctctcc tgcgaggcgg tgagcgggga 200

 gcccgcagcc gccagcgcag gggcccccgc ggccatgctt agtgacaccg 250

 acgccgggga cgcatttgcc agcgctgcgg cagtggccaa gccggggccc 300

 ccggacggcc gcaagggctc cccctgcggg gaggaggagc tgccctccgc 350

 cgctgcagcc gccgccgccg ccgccgccgc ggctgcggcc actgcgcgct 400

 actccatgga cagcctgagc tccgagcggt actacctcca gtcccccggt 450

 cctcaggggt cggagctggc tgcgccctgc tcactcttcc cgtaccaggc 500

 ggcggctggg gcgccccacg gacctgtgta cccggctcct aacggggcgc 550

 gctaccccta cggctccatg ctgccccccg gcggcttccc cgcggctgtg 600

 tgcccacccg ggagggcgca gttcggccca ggagccggtg cgggcagtgg 650

 cgcgggcggt agcagcggcg ggggcggcgg cccgggcacc tatcagtaca 700

 gccagggggc tccgctctac gggccgtacc ctggagccgc agcggcggga 750

 tcttgcggag gactgggggg cctgggggtt ccaggttctg gcttccgtgc 800

 ccacgtctac ctgtgcaacc ggcctctgtg gctcaaattc caccgccacc 850

 aaactgagat gatcattacg aaacagggca ggcgcatgtt tcctttcttg 900

 agcttcaaca taaacggact caatcccact gcccactaca atgtgttcgt 950

 agaggtggtg ctggcggacc ccaaccactg gcgcttccag gggggcaaat 1000

 gggtgacctg tggcaaagcc gacaataaca tgcagggcaa caaaatgtat 1050

 gttcacccag agtctcctaa tactggttcc cactggatga gacaggagat 1100

 ttcattcggg aaattaaaac tcaccaataa caaaggcgca aataacaaca 1150

 acacccagat gatagtctta caatccttac acaaatacca accccgactg 1200

 catattgttg aagttacaga ggatggcgtg gaggacttga atgagccctc 1250

 aaagacccag acttttacct tctcagaaac gcaattcatt gcagtgactg 1300

 cctaccaaaa caccgatatt actcaactaa agattgatca taaccccttt 1350

 gcaaaaggct tcagagacaa ctatgattca tcccatcaga ttgtccctgg 1400

 aggtcggtac ggcgttcaat ccttcttccc ggagcccttt gtcaacactt 1450

 tacctcaagc ccgctattat aatggcgaga gaaccgtgcc acagaccaac 1500

 ggcctccttt caccccaaca gagcgaagag gtggccaacc ctccccagcg 1550

 gtggcttgtc acgcctgtcc agcaacctgg gaccaacaaa ctagacatca 1600

 gttcctatga atctgaatat acttctagca cattgctccc atatggcatt 1650

 aaatccttgc cccttcagac atcccatgcc ctggggtatt acccagaccc 1700

 aacctttcct gcaatggcag ggtggggagg tcgaggttct taccagagga 1750

 agatggcagc tggactacca tggacctcca gaacaagccc cactgtgttc 1800

 tctgaagatc agctctccaa ggagaaagtg aaagaggaaa ttggctcttc 1850

 ttggatagag acaccccctt ccatcaaatc tctagattcc aatgattcag 1900

 gagtatacac cagtgcttgt aagcgaaggc ggctgtctcc tagcaactcc 1950

 agtaatgaaa attcaccctc cataaagtgt gaggacatta atgctgaaga 2000

 gtatagtaaa gacacctcaa aaggcatggg agggtattat gctttttaca 2050

 caactcccta aagagttatt ttaacctcaa aaattagcta actttttgca 2100

 gatggacttg gtggtgtttt ttgttgtctt ctttgcctag gttgccaaaa 2150

 agatgtttgc cttccacctt gatgcatcct gttttgtgca attctctaaa 2200

 agaaggtgcc aaagcttttt gattgctgca ggtaactgaa acaaacctag 2250

 catttttaaa aaataagatt aatggaagac tttaaggtat tttaaaattc 2300

 gaagggtatc caaggttctg tatttattta ttggggagac actaaccctt 2350

 caaagaagca ggctgtgaac attgggtgcc cagtgctatc agatgagtta 2400

 aaacctttga ttctcatttc tatttgtaaa ttcttaagca aatagaagcc 2450

 gagtgttaag gtgttttgct tctgaaagag ggctgtgcct tccgtttcag 2500

 aaggagacat tttgctgtta cattctgcca ggggcaaaag atactaggcc 2550

 caggagtcaa gaaaagcttt tgtgaaagtg atagtttcac ctgactttga 2600

 ttccttaacc cccggctttt ggaacaagcc atgtttgccc tagtccagga 2650

 ttgcctcact tgagacttgc taggcctctg ctgtgtgctg gggtggccag 2700

 tgggactcag gagagagcaa gctaaggagt caccaaaaaa aaaaaaaaaa 2750

 aaaaaa 2756

<210> 4858
<211> 686
<212> PRT
<213> Homo sapien

<400> 4858
 Met Gln Leu Gly Glu Gln Leu Leu Val Ser Ser Val Asn Leu Pro
   1               5                  10                  15

 Gly Ala His Phe Tyr Pro Leu Glu Ser Ala Arg Gly Gly Ser Gly
                  20                  25                  30

 Gly Ser Ala Gly His Leu Pro Ser Ala Ala Pro Ser Pro Gln Lys
                  35                  40                  45

 Leu Asp Leu Asp Lys Ala Ser Lys Lys Phe Ser Gly Ser Leu Ser
                  50                  55                  60

 Cys Glu Ala Val Ser Gly Glu Pro Ala Ala Ala Ser Ala Gly Ala
                  65                  70                  75

 Pro Ala Ala Met Leu Ser Asp Thr Asp Ala Gly Asp Ala Phe Ala
                  80                  85                  90

 Ser Ala Ala Ala Val Ala Lys Pro Gly Pro Pro Asp Gly Arg Lys
                  95                 100                 105

 Gly Ser Pro Cys Gly Glu Glu Glu Leu Pro Ser Ala Ala Ala Ala
                 110                 115                 120

 Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Thr Ala Arg Tyr Ser
                 125                 130                 135

 Met Asp Ser Leu Ser Ser Glu Arg Tyr Tyr Leu Gln Ser Pro Gly
                 140                 145                 150

 Pro Gln Gly Ser Glu Leu Ala Ala Pro Cys Ser Leu Phe Pro Tyr
                 155                 160                 165

 Gln Ala Ala Ala Gly Ala Pro His Gly Pro Val Tyr Pro Ala Pro
                 170                 175                 180

 Asn Gly Ala Arg Tyr Pro Tyr Gly Ser Met Leu Pro Pro Gly Gly
                 185                 190                 195

 Phe Pro Ala Ala Val Cys Pro Pro Gly Arg Ala Gln Phe Gly Pro
                 200                 205                 210

 Gly Ala Gly Ala Gly Ser Gly Ala Gly Gly Ser Ser Gly Gly Gly
                 215                 220                 225

 Gly Gly Pro Gly Thr Tyr Gln Tyr Ser Gln Gly Ala Pro Leu Tyr
                 230                 235                 240

 Gly Pro Tyr Pro Gly Ala Ala Ala Ala Gly Ser Cys Gly Gly Leu
                 245                 250                 255

 Gly Gly Leu Gly Val Pro Gly Ser Gly Phe Arg Ala His Val Tyr
                 260                 265                 270

 Leu Cys Asn Arg Pro Leu Trp Leu Lys Phe His Arg His Gln Thr
                 275                 280                 285

 Glu Met Ile Ile Thr Lys Gln Gly Arg Arg Met Phe Pro Phe Leu
                 290                 295                 300

 Ser Phe Asn Ile Asn Gly Leu Asn Pro Thr Ala His Tyr Asn Val
                 305                 310                 315

 Phe Val Glu Val Val Leu Ala Asp Pro Asn His Trp Arg Phe Gln
                 320                 325                 330

 Gly Gly Lys Trp Val Thr Cys Gly Lys Ala Asp Asn Asn Met Gln
                 335                 340                 345

 Gly Asn Lys Met Tyr Val His Pro Glu Ser Pro Asn Thr Gly Ser
                 350                 355                 360

 His Trp Met Arg Gln Glu Ile Ser Phe Gly Lys Leu Lys Leu Thr
                 365                 370                 375

 Asn Asn Lys Gly Ala Asn Asn Asn Asn Thr Gln Met Ile Val Leu
                 380                 385                 390

 Gln Ser Leu His Lys Tyr Gln Pro Arg Leu His Ile Val Glu Val
                 395                 400                 405

 Thr Glu Asp Gly Val Glu Asp Leu Asn Glu Pro Ser Lys Thr Gln
                 410                 415                 420

 Thr Phe Thr Phe Ser Glu Thr Gln Phe Ile Ala Val Thr Ala Tyr
                 425                 430                 435

 Gln Asn Thr Asp Ile Thr Gln Leu Lys Ile Asp His Asn Pro Phe
                 440                 445                 450

 Ala Lys Gly Phe Arg Asp Asn Tyr Asp Ser Ser His Gln Ile Val
                 455                 460                 465

 Pro Gly Gly Arg Tyr Gly Val Gln Ser Phe Phe Pro Glu Pro Phe
                 470                 475                 480

 Val Asn Thr Leu Pro Gln Ala Arg Tyr Tyr Asn Gly Glu Arg Thr
                 485                 490                 495

 Val Pro Gln Thr Asn Gly Leu Leu Ser Pro Gln Gln Ser Glu Glu
                 500                 505                 510

 Val Ala Asn Pro Pro Gln Arg Trp Leu Val Thr Pro Val Gln Gln
                 515                 520                 525

 Pro Gly Thr Asn Lys Leu Asp Ile Ser Ser Tyr Glu Ser Glu Tyr
                 530                 535                 540

 Thr Ser Ser Thr Leu Leu Pro Tyr Gly Ile Lys Ser Leu Pro Leu
                 545                 550                 555

 Gln Thr Ser His Ala Leu Gly Tyr Tyr Pro Asp Pro Thr Phe Pro
                 560                 565                 570

 Ala Met Ala Gly Trp Gly Gly Arg Gly Ser Tyr Gln Arg Lys Met
                 575                 580                 585

 Ala Ala Gly Leu Pro Trp Thr Ser Arg Thr Ser Pro Thr Val Phe
                 590                 595                 600

 Ser Glu Asp Gln Leu Ser Lys Glu Lys Val Lys Glu Glu Ile Gly
                 605                 610                 615

 Ser Ser Trp Ile Glu Thr Pro Pro Ser Ile Lys Ser Leu Asp Ser
                 620                 625                 630

 Asn Asp Ser Gly Val Tyr Thr Ser Ala Cys Lys Arg Arg Arg Leu
                 635                 640                 645

 Ser Pro Ser Asn Ser Ser Asn Glu Asn Ser Pro Ser Ile Lys Cys
                 650                 655                 660

 Glu Asp Ile Asn Ala Glu Glu Tyr Ser Lys Asp Thr Ser Lys Gly
                 665                 670                 675

 Met Gly Gly Tyr Tyr Ala Phe Tyr Thr Thr Pro
                 680                 685

<210> 4859
<211> 1887
<212> DNA
<213> Homo sapien

<400> 4859
 tttccaaaat gaagcaccca aaagggtagt agaacgaacc cttctggaac 50

 agtttgcaga taaaaatctt agctatgatg aaagatcaat cagcattatg 100

 aaggtggctc aagcgaaact gaaggaaatt ggtccagatg acatgaatat 150

 ggaagagtac aagaagtggc atgaagatta tagtttgttc cgaaaagtgt 200

 ctgtgtatct cctaacaggc ctagaactct atcaaaaagg aaagtaccaa 250

 gaggcacttt cctacctggt atatgcctac cagagcaatg ctgccctgct 300

 gatgaagggg ccccgccggg gggtcaaaga atccgtgatt gctttatacc 350

 gaagaaaatg ccttctggag ctgaatgcca aagcagcttc tctttttgaa 400

 acaaatgatg atcactccgt aactgagggc attaatgtga tgaatgaact 450

 gatcatcccc tgcattcacc ttatcattaa taatgacatt tccaaggatg 500

 atctggatgc cattgaggtc atgagaaacc attggtgctc ttaccttggg 550

 caagatattg cagaaaatct gcagctgtgc ctaggggagt ttctacccag 600

 acttctagat ccttctgcag aaatcatcgt cttgaaagag cctccaacta 650

 ttcgacccaa ttctccctat gacctatgta gccgatttgc agctgtcatg 700

 gagtcaattc agggagtttc aactgtgaca gtgaaataag ctcccacatg 750

 ttcaaggccc attctggttc ctggctgcct gcctcttgca cagaagttcg 800

 ttgtcatagt gctcaccttg ggaaaaggat taggtgggca cataagattc 850

 cgatcagacc ccaaccatgc tgcatgtgta aagaaggatt gaaaataaaa 900

 ttgcactttt taggtacaaa atcataaaag ctgtttcact agaaaaggca 950

 gaaagcagtg tattaaggtg ttgaattacg ccagaagacc tgaaatgcct 1000

 tgtacctaca acaatgctta ggcttttcta agcctcttgc cacttttaaa 1050

 attatccttc aggcataaat atttttgaca gcagaataga agaatgattc 1100

 atgagaacct gaaccagatg aacagctact agttatttta tcaaatacag 1150

 atgacattta aaaattctta actacaagag attagaaata taaccttgcc 1200

 tggctcttgc caggagataa caaaatgggt tgctgatgaa ctgcaccctt 1250

 ttacatgtgg gtagaatata agctcacatg gcagtgagat gttgaaaagt 1300

 caaaagagac ctgtctctct cctttctttt ctatctttaa accagaaaac 1350

 ctcatactca gtcctcagtg aaagaaagta aagtattaag gactttagac 1400

 agaagagcat tgtgtaactt gactgaaggt catccattaa tagttattag 1450

 gcatttaggt aaaattttct aatacctaaa aattgtcaaa aacagtcaat 1500

 agggctactg ctggcccaaa gaccatttag gtccacctcc tcttttttgc 1550

 tctttttttt ttttctgtga cagtttcact gtgtcgccca ggctggcgtt 1600

 cagtggtgca atctcagctc actgcaaact ctgtctcctg ggctcaagtg 1650

 attctcgtgc ctcagcctcc cgaatagctg gaattacggg catgcaccac 1700

 cacacctggc taatttttgt atttttaata gagatggggt ttcaccatat 1750

 tggccaggct gatctctaac tcctggcctc aagtgatcta tctgcctccc 1800

 tcagcctccc aaagtctggg attgcagaca agtcatcgta cccggccttc 1850

 ttttttgccc ttaaaagtaa gggatgtggg tttgtac 1887

<210> 4860
<211> 213
<212> PRT
<213> Homo sapien

<400> 4860
 Met Lys Val Ala Gln Ala Lys Leu Lys Glu Ile Gly Pro Asp Asp
   1               5                  10                  15

 Met Asn Met Glu Glu Tyr Lys Lys Trp His Glu Asp Tyr Ser Leu
                  20                  25                  30

 Phe Arg Lys Val Ser Val Tyr Leu Leu Thr Gly Leu Glu Leu Tyr
                  35                  40                  45

 Gln Lys Gly Lys Tyr Gln Glu Ala Leu Ser Tyr Leu Val Tyr Ala
                  50                  55                  60

 Tyr Gln Ser Asn Ala Ala Leu Leu Met Lys Gly Pro Arg Arg Gly
                  65                  70                  75

 Val Lys Glu Ser Val Ile Ala Leu Tyr Arg Arg Lys Cys Leu Leu
                  80                  85                  90

 Glu Leu Asn Ala Lys Ala Ala Ser Leu Phe Glu Thr Asn Asp Asp
                  95                 100                 105

 His Ser Val Thr Glu Gly Ile Asn Val Met Asn Glu Leu Ile Ile
                 110                 115                 120

 Pro Cys Ile His Leu Ile Ile Asn Asn Asp Ile Ser Lys Asp Asp
                 125                 130                 135

 Leu Asp Ala Ile Glu Val Met Arg Asn His Trp Cys Ser Tyr Leu
                 140                 145                 150

 Gly Gln Asp Ile Ala Glu Asn Leu Gln Leu Cys Leu Gly Glu Phe
                 155                 160                 165

 Leu Pro Arg Leu Leu Asp Pro Ser Ala Glu Ile Ile Val Leu Lys
                 170                 175                 180

 Glu Pro Pro Thr Ile Arg Pro Asn Ser Pro Tyr Asp Leu Cys Ser
                 185                 190                 195

 Arg Phe Ala Ala Val Met Glu Ser Ile Gln Gly Val Ser Thr Val
                 200                 205                 210

 Thr Val Lys


<210> 4861
<211> 2932
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1350-1408, 2345-2512
<223> Unknown base

<400> 4861
 atagcgttac cataggaaac tgttccaaac tgagttagct ttaattataa 50

 ttattttatt cataaatggt gatagtcccc agatctgtac acctttatca 100

 ctccctgccg tagatatact ttaggttagt atttctacat tcgtggcaag 150

 cattttggta acaccagtgg ttttcattgt gacttttatc actatcacta 200

 agaatgcaat ttaagttgcc ttttggcatc atagatcata gaaactttct 250

 ctctgaatca tacccatgtg tgaattttca ttttatatga tagtgtagca 300

 tattagaagc atattttaaa acagagcctt tgagaaattg aaaaacaatt 350

 atttgaagtt caccatagta ccttaaagga acaaagagaa tgtgggatag 400

 gagtaacttg aattcgtgtt tagtatggtg ggctttgaat ttttttcact 450

 atcaaaaata gtgcttttgt ttagttaaaa attgtagttt ttcttttttt 500

 gtgtgtccaa actaacataa aaggagtggt caaagaagga aagaagaaaa 550

 atgagggagg atgtccgaaa ctgtatggca ttttactcct tctgaaagag 600

 aaatactgta cttgaatttt tgagctatgc agacttatac ctagattgtt 650

 gtgtttcttt gattcttagg agaaaagctt tcttcctaat aattcttgag 700

 aactttatat tttgtttgaa aacagtttct atgtacataa aaagggtatt 750

 tacccatttg tgagcactta aaacactcca cagagtcaga cagtgggaaa 800

 ggtcaccctt tttttattcg gcaggtatca agttagaatg tatggaattg 850

 tgaataaaat tatattttat tttatgaaaa tatttttata taataaaatt 900

 taaaaggctg gtaagctaaa aaaatagtct tctttaatcc tagtgtgttt 950

 tccccaattt agtcttttct aaaatttatc tgttttagag tagaaaatat 1000

 tatatcctga gaatcacaga atcatctaaa tatgtcttat tcaactgaag 1050

 tgattgtaag tctttattct tgtgctttgg ttaaatgaat gataatttag 1100

 ttgatagtga aagttaatgt gtttttatat ttttagagtg agggaaaaat 1150

 actaaacttt tgagagtttt gttgtcgttg ctggtttttt accatgtggt 1200

 actaaattcc actttgatac aaaatttaaa ttttgtaact tctcaaaatc 1250

 acttaagatt cttcagtttt acctgtgctt cttgacatcg ctcctataat 1300

 gtatgttagt taactctgca tatggcaaat cttgtcttga attatatcan 1350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1400

 nnnnnnnnag tgtggggggt attgttatga gtaaaacttt atcaaaactt 1450

 ggcctgaaaa agagataact catgatccat tgctatcttt attactcaaa 1500

 ggctgttcat tcccataata ccagatccat aatagttgta gtttttttga 1550

 tgttgttgcc cttaccttaa ttatttgtag ttttagtagg ccttgcctca 1600

 gtttttccca cagaattcca taattttaat gttgaactaa cccatctata 1650

 taggacttct aaaaactacg tcaggaatgt aaggttaaat gagaggtaga 1700

 acttgtagtg taataggtat aatggtagct ttcaaagttt tatcttctca 1750

 aaacattgtc ttagccagtg tatttctgag aactcagact gaagcacaga 1800

 agtcacagta tgcttctttt atttaagcac acagattcat gacacaagta 1850

 cttgttgaac aagtgttctc attgcagaga gatctacttg aatataaaag 1900

 ggtcatcata ctagattatt aaaaagaatt ggaaatcttg agttgtggaa 1950

 gaaatgttta tgctttggag atctaaaaaa gttatgaatg taggaattag 2000

 ataagtccag tttgttctgt taatataaaa tggttagata tattaaactg 2050

 caagtagtat cagcttcacc ataagcttgg gccttcctcc atcttgtttt 2100

 atttaagtct ctttaaatga aattttgttg tcattgtttc agcattcatg 2150

 aactttctta ctatcacagg ttctacttta attttccttg ccatatgtgt 2200

 ttccattttg tgggacatta gccaccacag gaacacaaga gttgtcagaa 2250

 gactcctggg tgtacagagc aaatcaagct gcatcagtat tataggatac 2300

 caaacagaat cctttctatt aggaaataag aaatcagtta agtgnnnnnn 2350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2500

 nnnnnnnnnn nncagtccac ctttctaggc cttggttcct tgcctgaaaa 2550

 atgaaagagg cgctggcttt ccacagtgtc atgctttggc actttagcta 2600

 tggttttctt tctgtgtgtg tgtaagccac tgcttataat aaaaccaaca 2650

 ataccctcag actgaaaggg cggaagttat tatctgcatc tttatcaacc 2700

 ccaagcccca cttcctccct gacctcccca tgccctcccc agcctctccc 2750

 agcacaagtg gggcaaagcc agcatgcaag cagaccccac caccacagcc 2800

 cacctccgtc ctcacatacg tgcaggctgg ctcgggagtc cagtgagcag 2850

 agcattggac ttggctggcc agagggtctc tgagggcaag agacatggcc 2900

 aaccaagggc aaggagtgac cctgtggagg gt 2932

<210> 4862
<211> 126
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 66-122
<223> unknown amino acid

<220>
<221> Unsure
<222> 1350-1408, 2345-2512
<223> Unknown amino acid

<400> 4862
 Met Asn Phe Leu Thr Ile Thr Gly Ser Thr Leu Ile Phe Leu Ala
   1               5                  10                  15

 Ile Cys Val Ser Ile Leu Trp Asp Ile Ser His His Arg Asn Thr
                  20                  25                  30

 Arg Val Val Arg Arg Leu Leu Gly Val Gln Ser Lys Ser Ser Cys
                  35                  40                  45

 Ile Ser Ile Ile Gly Tyr Gln Thr Glu Ser Phe Leu Leu Gly Asn
                  50                  55                  60

 Lys Lys Ser Val Lys Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 110                 115                 120

 Xaa Xaa Ser Pro Pro Phe
                 125

<210> 4863
<211> 7981
<212> DNA
<213> Homo sapien

<400> 4863
 tggaaacaaa gaagtatttt cctgcagagg aataaaattg gcagtggatt 50

 ggtttttgga aagaggccac aaagacatta cagtttttgt tcctgcttgg 100

 aggaaagagc aatcccgacc tgatgctctc attacagatc aggaaatttt 150

 acgtaaatta gagaaggaga aaatcctggt gttcacgcca tcccggcgag 200

 tccaggggag gagagtggtg tgctatgacg acaggttcat cgtgaagctg 250

 gcttttgagt cggacggtat cattgtgtcc aatgataact acagggactt 300

 ggctaatgag aagccagaat ggaagaagtt catagatgaa cgattattaa 350

 tgtattcatt tgtcaatgac aagttcatgc cccctgatga ccctcttggc 400

 agacatggcc ccagtctgga taattttctg aggaagaaac ctattgttcc 450

 tgaacacaaa aagcagcctt gtccatatgg aaagaagtgt acctatggac 500

 acaagtgcaa atattaccat cccgaaaggg gcagtcagcc acagcggtca 550

 gtggctgatg aactccgtgc catgtctaga aatacggcag ccaaaactgc 600

 aaacgaagga ggactggtga aaagcaacag tgttccttgt agcaccaagg 650

 ctgatagcac ttctgatgtc aaacgaggtg ctccaaagag gcaatcagat 700

 ccaagcataa ggacacaagt ctaccaagac ctagaagaaa agcttcccac 750

 caaaaacaaa ttggaaacca ggtctgtacc ttccttagtt agcatcccag 800

 ctacttctac tgcaaaaccc caaagcacta catctttaag caatggcctt 850

 ccatctggag ttcatttccc acctcaggat caaagaccac agggacaata 900

 tccttcaatg atgatggcaa ccaaaaatca tggaacgcca atgccttatg 950

 aacagtatcc aaaatgtgac tcacctgtcg acatcggata ttattccatg 1000

 ttgaatgcat actcaaatct gagtctctca ggcccacgaa gccctgaaag 1050

 gcgtttctcc ttagacacag attatagaat aagttccgta gcttctgact 1100

 gcagcagtga agggagcatg agctgtggga gcagtgactc ctacgtgggt 1150

 tacaatgacc ggtcctatgt cagctccccc gacccacagc tagaggagaa 1200

 tttgaagtgt caacacatgc accctcacag ccgccttaat cctcaaccgt 1250

 tcctgcagaa tttccacgac cccttaacca gagggcaaag ttacagtcac 1300

 gaagaaccaa agttccatca caagcctcct cttccgcacc tggctctgca 1350

 cctgccgcac tccgctgtgg gcgcccggtc cagctgtcct ggcgactacc 1400

 cctctcctcc aagttcagca cactctaagg caccacacct agggaggtcc 1450

 ttggtggcca cgagaataga cagcatctct gactctcgac tttatgacag 1500

 ttctccttca cgacaaagaa agccttattc ccgccaggaa ggcctgggaa 1550

 gctgggagag gccaggctat gggatcgacg cctatgggta ccggcagact 1600

 tattccttgc ccgataactc cacacagccg tgttatgagc agttcacctt 1650

 ccagagcctc cctgagcaac aggagccagc ctggcggatc ccatactgtg 1700

 gaatgccgca agatcccccg aggtatcaag acaaccgaga aaagatttat 1750

 atcaatttgt gcaacatctt cccccctgac cttgtgagaa ttgtcatgaa 1800

 aaggaatcct cacatgacag acgcccagca gctcgccgca gccattttag 1850

 tggagaaatc ccagctgggt tattgaaaga tgatgcatct ttgtggtgtt 1900

 tagtagtttt ttgttcagct caaatgctga gggaggtttg ctacaatagc 1950

 acatgtgatc tccttctcag caaggaggtt atatagtatc catttatgtg 2000

 aaatactgta tcatggaatc tgtatgtata gccccacatg gtggaagtat 2050

 cacgggattg ctttacattt aaactttttt ttttttaaca tttccttttt 2100

 aaagctatat ccttggctgg aaatttttcc agtttgattt aatagatgta 2150

 tctgtgatct ttgatattaa tctttggtgc atcaggggtt tatatgcagc 2200

 actttttatc cttgttttgt gttttattaa cttggtgttt gtctatcaat 2250

 tgcaagcaat tacaatacct tcagaatgtg ggacatttga ctagacctag 2300

 caaactgttt tttcgagcca agcttagtta gactctttta cagcttttta 2350

 agttattttt atttggggaa agtgggcttc tttgtgctat aatcattatt 2400

 tatagaaaca aagttatact acagcactga ctttatattt taaacagaat 2450

 gtaagttacc agttttatgt tgaaatgtgt tacagtatat atatattaga 2500

 atgatttaca atatggcact tttcgatgtg ttatttttgt ttggattttt 2550

 ttttctgtta agaaattagt taatttaata tggtcaattt aaaagaaagc 2600

 agatgcaatc aatggaaaaa tgtttccatt ttttaaaaat gaataaggca 2650

 aaagctgtaa ctgttacagg ttagagcttt gttatccagc tatgatgtgc 2700

 ttcttgacag tagaagtgga attgaattcc tagatttcca ttaacctgta 2750

 tttttaatat gtctgtcttt ttgttttggg gcacaacaat actggataaa 2800

 ataacccttt cacagcactt gcctgttttt aatgaatcta attattcaca 2850

 atgcaacttt tatatttaac atactcttta gctttcctgc tatttatcaa 2900

 ggctggcctg aggtgggttt atgtgttgag gttatgcaac atttcttgat 2950

 actgcactat agagaaatgg tgatggagga gttgtaaatg gtaacttaaa 3000

 atttttgtaa gatattgtat attttccatt ttcctgaagg tagttttctt 3050

 gggggggcct gttatattat taaggccaga ctcttgccac aaatagtgta 3100

 gttttagata cagactaagg tctgttctag tattagtaag ggatatttct 3150

 ggtttcaaag tcatgggttt tgctagtggt gaatacattt ctgcggagta 3200

 gaagatagat tttgcagtca gtggcagaca gttgtgtgat tgacatcact 3250

 tgactgttgc gtccaggttt tgaattgtac ttcacgtaac agatgcattc 3300

 agatcttttt ctgtagtctg cttagatgcc ctggctattc tgattatcct 3350

 acatgctaca gtttgaagtg aagccctgaa aaaccagaaa gtacctttta 3400

 ctgttgatac aaattgtatc tttttaacta taagaactat tttgatttgt 3450

 agatctagtt aaaacacaag tatgtaacta tgattagact tttgggcaac 3500

 attttatccc ttatttaaat acaaattttt aaagtaaaat tgaggtctag 3550

 aatagattag aaaataaaaa taacaattta gataaataga aatgtctgtc 3600

 ttagttttat ataatatatt aaaacacagt aaataaattt attggcattt 3650

 tctttctcct aaaacttacc tagtgtgaac ttaaaataaa ggtaaaatgc 3700

 tgcctgaaaa taatgtccaa gcacctttga ctaggataac attttcacta 3750

 cttgtgtgac actgtgtgtt gcacgaagta ggatttgggt atacagtaaa 3800

 tgcttctaaa aggcattgtg catattgaca taaccaataa tctgaaccgt 3850

 gttcagcaaa cttaattcag gaaagtggta ttctacacaa ttattgctgt 3900

 tgtgtttgaa atgagtgtgg cactcatctg tatccagaaa taatatgggt 3950

 gaggccacac aacccattct gagtggtgtc tgtctgaaag caaccctact 4000

 cgcatgtgaa attgttctcc ttgatttggt cactataaag caagtttaaa 4050

 tgtagaggct aactcagtgc caaaaacagg gttacaaatg tgtagtatct 4100

 tttattttag tcatattcta agacttcttt ttagtatgaa atcactttta 4150

 aattatacat gtaggttttg cttccatttt cttcatttta ccattttaat 4200

 tatttgaaca ttcgccaaat tttacattta tttaaatgag atcttaggtg 4250

 agatgtgtgt gacactttga atttgacctt cttgtgttat tagctgacta 4300

 tttgtcattg cctcatggat tttaaattat gggaaaatag tgtagccagc 4350

 tgccacctct actgaagtga gtagctctga actacccaca ctaaatcctt 4400

 cagtgtaatt aattatgagt ttaaaaatag cagttttctt atgtgaagag 4450

 gacagtttgt cccctttttt tgaagcaccg atgttgcgtt cagagctgta 4500

 gaatgagata attggcagac tttaggtaca gcaaattctt acttatctaa 4550

 agcaataagt caaaggagtc catcattaaa ttaaatccat agctgatcac 4600

 aagccttcat tttagccaaa actttctctc taaccaaatc ttttaccaga 4650

 cttgctaata aataaccaga gagatgtgtt aataagtgaa gttgccagaa 4700

 atggtcaact gatcggaaaa aaaaggattc agactggagt attttgcccc 4750

 tgaataattg acagttgact gtgctttaca cagtaactag ccagtctgtt 4800

 gtctctgtgt cttagtccag agggaatagt acccaattgg ccaaatactg 4850

 gcccttagta tctcctcctt tcttgcatgg gatacagacg ttttcagtct 4900

 tgtttttatg atctctctct atatcctgat aagagtttgt cattgactta 4950

 cacatttgga agaaatgcac accagtgtaa tatatttgat actggtggaa 5000

 acttgaactt tgtgttttta tgaaaattca tttatgagaa tatgtaatat 5050

 aactgaagag tattttatgt atatctatat acacaaatat gtatttgtta 5100

 tgaggtatta aaaacagggg ttggggggag tgcttctgat ggctaacttt 5150

 tctctaatta aactatgttt ctttgagttg tgaacgaccg agtctggggt 5200

 ctggacggcc aatgataaga tttagaacca cttggatgga aagcagttct 5250

 tcactggttt tattcttggt attttcaaag aattattttg atatttttaa 5300

 tagaatgtgt aattttaaaa tacacaaaaa acttaaagta gtattgatta 5350

 tacaaataat tatttaacat gtcttatgga tgtatctata tgtatataga 5400

 cagtaatata tttataaaac aaatatactt tgcttatgtt atagctctta 5450

 gtttgtgaca ggtgggagga tggctctggg tgtgtgtgtg tgtgtgtgtg 5500

 tgtgtgtgtg tgtgtgtgtg tgttttgaaa actctcaagc tgttttccct 5550

 ctgatttaca atggtattta ctttaaagta tgtttggttt tcattattct 5600

 ttttgctctc caacttcctt attcaagata aaataagaca tacagttttc 5650

 tggccattct gttggtgtgt ggtgcaccca ttttattgtc atctaactcc 5700

 tggagaattc ccacgtgacc tgaaatcaaa cagattctgg ctggacatat 5750

 gcttatgttc caaatatatt aaagatgtta attcagctaa cagttaagtt 5800

 tccaaggtat acaccaacaa ataaaatgag gtattaaaaa gagatggatt 5850

 acacacatgc attagaataa gagaaaacag tagtgttaat aaaagtaaag 5900

 aaacatacac tatcttagcc ccctagggca ggggttgact ttttctgtaa 5950

 aggatcagat agtaaataat acaggaatca tatggacttc aaatgccatt 6000

 gtaaaaacta ctcagctctg cctttagagc ataagaacag ccacagataa 6050

 catgtaaatt agtgtggctg tgttccaata aaactttatt tacagaaacg 6100

 ggaagccggt cagattgggc ctgtgggcca taatttgctg atctcaagca 6150

 gtaaatcctg gtatatgtta atagaagaaa tcataattgc atttcagttg 6200

 acattaaaag aaaatctggt agtttttgat gtccttcaaa agaggattgt 6250

 tagacattga tgttaaagca tcttaattca tttgagtttt cttacctgtt 6300

 tacacccatt atttattaga gatatttctt gtgtttaacc acaaaaaaaa 6350

 gcactctgtt aaaatgtttt aatatgtatt gaatttcttt cataaacttt 6400

 tcatttctgt tgataaatgg gaatccctta ccaacctttt gttttttaaa 6450

 agtctcatag accaaaaaaa atctgttgca gcatttaatt agccacagat 6500

 acattttggc tgcatttacc agttacattt ttccattggt tttggcttct 6550

 aataaataac atatctgcca ttccttaaaa atgattttaa agaagataaa 6600

 tatattgtaa tttcacatgc tatagcttta ttctgtaaga ttaaaaattg 6650

 tgactagtat aattgtagct ataatgtgag tggcatgtta caatgtaact 6700

 ctttatgaga aataaaatgt atctctgctt tgtctgtcca gatctttagg 6750

 atttttagat gccttgggac tgtccttggt gaatgatatt cttcatatga 6800

 tcatatgtaa ttttgaattc gttggaagta cacgctgctg agcatgttta 6850

 ttcacagtgc tttataccgg gtgttgcatc agtaatcatt ttcataagaa 6900

 catttaaaca gcatgaacat catcatccac ttaaatagtt aaactttctt 6950

 ttaaaattgg aatgcaactg taggttttaa caatgtttat tgttttttaa 7000

 gtggttactt tgtttttcct taatactttc tgttaactta attattactc 7050

 ctgttgcagt gttactgtta tgtattagaa gtggcttttc cccctaagat 7100

 ccttagtctt ttaaagacaa tttaaggtat tggccatttg gcagtagaaa 7150

 atgtgcatgt tttaacttgg ttttataaaa tctgtaatgt ttcacttctt 7200

 gaaccatgta ccaaatttgc caattttctg tccaagtgtt tcagatgaat 7250

 aacaaaacgc tgttcattga agctttcgcc acctttctta aagcagcgta 7300

 tgttccaagg gaaaaaggca ttgaaaagca atcgtttgtt tttatgaaga 7350

 ataggtgttc agattccttc agtttttttg aaattagaaa tttcttacct 7400

 tatgtgaaat attcacaaac gtgcacactt ctgcagagac aaagcatttc 7450

 actgcacgtg taccaggtta ttgattttat cttttccttt cagggttttg 7500

 tcctcccaaa ccagagtcat atgctgctag tagaattttt tatttgatcc 7550

 tgcgaacttt tcttatagga aaagtaaggc aaaggatgtg tagtgcaacc 7600

 atctgataaa ctagtgtgat tgtatttatc ctctgttctg tgtatttctg 7650

 taatggaatc tttacaattc ccaaaacggt attttagacc tactggaaat 7700

 ctgtatcgaa acagctatgt gattctgcca ctgagaaaaa aaaaattttt 7750

 aattcgtttt tcttatgctg gtttgttttt ctttaatgaa gaaattgatc 7800

 tcatatggca tcatagatgc taaataaata aaagcatcat acttctctag 7850

 tttgcctgca ttcagtggct aacattatga gcattgtgta agataaacac 7900

 atggtcagta tcaatgtaaa tgttagagcc atgattaatt cctatgaaaa 7950

 ttgaaattaa atgtcaaaga caactagaca t 7981

<210> 4864
<211> 624
<212> PRT
<213> Homo sapien

<400> 4864
 Gly Asn Lys Glu Val Phe Ser Cys Arg Gly Ile Lys Leu Ala Val
   1               5                  10                  15

 Asp Trp Phe Leu Glu Arg Gly His Lys Asp Ile Thr Val Phe Val
                  20                  25                  30

 Pro Ala Trp Arg Lys Glu Gln Ser Arg Pro Asp Ala Leu Ile Thr
                  35                  40                  45

 Asp Gln Glu Ile Leu Arg Lys Leu Glu Lys Glu Lys Ile Leu Val
                  50                  55                  60

 Phe Thr Pro Ser Arg Arg Val Gln Gly Arg Arg Val Val Cys Tyr
                  65                  70                  75

 Asp Asp Arg Phe Ile Val Lys Leu Ala Phe Glu Ser Asp Gly Ile
                  80                  85                  90

 Ile Val Ser Asn Asp Asn Tyr Arg Asp Leu Ala Asn Glu Lys Pro
                  95                 100                 105

 Glu Trp Lys Lys Phe Ile Asp Glu Arg Leu Leu Met Tyr Ser Phe
                 110                 115                 120

 Val Asn Asp Lys Phe Met Pro Pro Asp Asp Pro Leu Gly Arg His
                 125                 130                 135

 Gly Pro Ser Leu Asp Asn Phe Leu Arg Lys Lys Pro Ile Val Pro
                 140                 145                 150

 Glu His Lys Lys Gln Pro Cys Pro Tyr Gly Lys Lys Cys Thr Tyr
                 155                 160                 165

 Gly His Lys Cys Lys Tyr Tyr His Pro Glu Arg Gly Ser Gln Pro
                 170                 175                 180

 Gln Arg Ser Val Ala Asp Glu Leu Arg Ala Met Ser Arg Asn Thr
                 185                 190                 195

 Ala Ala Lys Thr Ala Asn Glu Gly Gly Leu Val Lys Ser Asn Ser
                 200                 205                 210

 Val Pro Cys Ser Thr Lys Ala Asp Ser Thr Ser Asp Val Lys Arg
                 215                 220                 225

 Gly Ala Pro Lys Arg Gln Ser Asp Pro Ser Ile Arg Thr Gln Val
                 230                 235                 240

 Tyr Gln Asp Leu Glu Glu Lys Leu Pro Thr Lys Asn Lys Leu Glu
                 245                 250                 255

 Thr Arg Ser Val Pro Ser Leu Val Ser Ile Pro Ala Thr Ser Thr
                 260                 265                 270

 Ala Lys Pro Gln Ser Thr Thr Ser Leu Ser Asn Gly Leu Pro Ser
                 275                 280                 285

 Gly Val His Phe Pro Pro Gln Asp Gln Arg Pro Gln Gly Gln Tyr
                 290                 295                 300

 Pro Ser Met Met Met Ala Thr Lys Asn His Gly Thr Pro Met Pro
                 305                 310                 315

 Tyr Glu Gln Tyr Pro Lys Cys Asp Ser Pro Val Asp Ile Gly Tyr
                 320                 325                 330

 Tyr Ser Met Leu Asn Ala Tyr Ser Asn Leu Ser Leu Ser Gly Pro
                 335                 340                 345

 Arg Ser Pro Glu Arg Arg Phe Ser Leu Asp Thr Asp Tyr Arg Ile
                 350                 355                 360

 Ser Ser Val Ala Ser Asp Cys Ser Ser Glu Gly Ser Met Ser Cys
                 365                 370                 375

 Gly Ser Ser Asp Ser Tyr Val Gly Tyr Asn Asp Arg Ser Tyr Val
                 380                 385                 390

 Ser Ser Pro Asp Pro Gln Leu Glu Glu Asn Leu Lys Cys Gln His
                 395                 400                 405

 Met His Pro His Ser Arg Leu Asn Pro Gln Pro Phe Leu Gln Asn
                 410                 415                 420

 Phe His Asp Pro Leu Thr Arg Gly Gln Ser Tyr Ser His Glu Glu
                 425                 430                 435

 Pro Lys Phe His His Lys Pro Pro Leu Pro His Leu Ala Leu His
                 440                 445                 450

 Leu Pro His Ser Ala Val Gly Ala Arg Ser Ser Cys Pro Gly Asp
                 455                 460                 465

 Tyr Pro Ser Pro Pro Ser Ser Ala His Ser Lys Ala Pro His Leu
                 470                 475                 480

 Gly Arg Ser Leu Val Ala Thr Arg Ile Asp Ser Ile Ser Asp Ser
                 485                 490                 495

 Arg Leu Tyr Asp Ser Ser Pro Ser Arg Gln Arg Lys Pro Tyr Ser
                 500                 505                 510

 Arg Gln Glu Gly Leu Gly Ser Trp Glu Arg Pro Gly Tyr Gly Ile
                 515                 520                 525

 Asp Ala Tyr Gly Tyr Arg Gln Thr Tyr Ser Leu Pro Asp Asn Ser
                 530                 535                 540

 Thr Gln Pro Cys Tyr Glu Gln Phe Thr Phe Gln Ser Leu Pro Glu
                 545                 550                 555

 Gln Gln Glu Pro Ala Trp Arg Ile Pro Tyr Cys Gly Met Pro Gln
                 560                 565                 570

 Asp Pro Pro Arg Tyr Gln Asp Asn Arg Glu Lys Ile Tyr Ile Asn
                 575                 580                 585

 Leu Cys Asn Ile Phe Pro Pro Asp Leu Val Arg Ile Val Met Lys
                 590                 595                 600

 Arg Asn Pro His Met Thr Asp Ala Gln Gln Leu Ala Ala Ala Ile
                 605                 610                 615

 Leu Val Glu Lys Ser Gln Leu Gly Tyr
                 620

<210> 4865
<211> 3828
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3065-3105
<223> Unknown base

<400> 4865
 gtgaaattga agtttgtgta tatgaaagtt atcttagaca tatttttaat 50

 tctccagttt ctgcaaaata attaaaatat acagtaactg gtctcctaaa 100

 tcctgaattt aatgtattaa atacttatgt tctttatatt ggtgcctttt 150

 taaaatgcat tgagagtgtt ggttagctgt tgcagctgta caacactttt 200

 aatatgcatt tttaaaaatc acttaaaatt gagtactata taattcatct 250

 ctgcattttt agtgcaaatc tttagagcaa tttctaatag agaaattttc 300

 agctcagctg ttaaaaggaa aaggaaactt tgaaactaga ctttactacc 350

 tttttagttt catagtattt ctgaatatga ttacaagatt atgcaggtaa 400

 aatatagagt gaaactttac ctgtgaattg aattataatt tgtgtttttg 450

 ttttgttttt aaggaagaat aagttctgta tcaaacaaga atttattaga 500

 taattttttg gtcaataaaa tacagtattc atttggattt tcatctccag 550

 actagtattg ttctagtctt ggaatctgta ttttctaatc tgttagaaaa 600

 tagagattga aaattgatgg aataatgtga aaaagcaggt aattaattct 650

 ccttgaacaa agcaaaactg aacagtcata tcacattgct attctccaaa 700

 gcataatctc aaatggtttc atatcatggt tgtgtattac ttgcaatggg 750

 tgtgttagga tatgacagct ttttaaaaaa atgagctgct ggttatacaa 800

 agcaaatggc atatgaccaa gaagctgtga tatgctagtg tttcttttta 850

 tcatagtgta ttactaggcc aaataatgac accttgaata tttttacatt 900

 tattgcagaa accttaaact tggaatttcc ataaggtttt tatgtaatat 950

 tctatttcta gctttttagt tttatcttgc tgtactgtaa gtttgaggat 1000

 atttttcacc tgcactctta ggaataagtt cataattctg tttatggggc 1050

 tttcctccca taacactgca tttgtatatt ttctgtataa aatatgtgtt 1100

 gtgtattaac ctttatccca tacagagagt ggtacatgaa tgactagttt 1150

 tctaagatgt cctttttatt gtgaataaaa tataaaagtt aaaggccctc 1200

 tgctaagtca cataaagtac agcatataag ttcatatagg tacaaataaa 1250

 tgagtttgca gtggattggg ccttcaaatt acctcaagtg acagatagta 1300

 agaaaagctt cttgagcagg tggaggtcac tgaatcccct actatgcact 1350

 tatcaagatt ttacttactt taatttactg gaaattgatt ttttaaaaaa 1400

 tgactacact gtaacaaggg aagggatctg ggtttttttg ttgttttatt 1450

 cttgtttttt ttaagtagtt caaattctga aactgtgatt taaaaatttt 1500

 ttacagtcaa gcattctgat tttgaacata actcccttcc ctttctgtgt 1550

 aacaaaggtc tctctgttat ctcttaaatt ttgttacatc tccctcagcc 1600

 tctttctttg tccgtctccc ttctgtcatt gtctatggat gtttacctct 1650

 ctgttctcct aaaagtttga agattaggtc aactcttatt tctagttcat 1700

 tggtaattta atcctaattt ttttttcgtg atttttgttg gttgtataat 1750

 ctgctgacgt atttttatac tcaagtgtag ttttctatta aaaagaaaag 1800

 tggttggatt aaaaatagta agctatgtaa ccctcatgtt actttcactt 1850

 tcaaatattg ggtacctaaa acattacttc agagattatg taatcctatt 1900

 atagtatgtt tgctttcctt tattgttgga ttttacattc tgatttggct 1950

 ttcctccaaa aaatgtatat catgaaagac tagacagtta tttgcaagtg 2000

 tttagaaagg tgttaaaaat gtaaagcaaa gagtcttaac tttctcctaa 2050

 ttgggagaaa aatgctttaa cattactata ataatattcc aggtttggag 2100

 ggggtctcca ggccccatat ttgctgttaa tagttggacc ttttagacca 2150

 tgtgttattt gcaatcccag aatgattgct tctgctatta gttaaaaaga 2200

 tactattctt ttctttctgt acaagtgcaa tactcccctt gaagtcttaa 2250

 aaactatggt gatttttttt tcttttctga cctattcttc ctttagctaa 2300

 tgacaaaaag aaactcataa aagtcatagt atgttaaagg acacaacaag 2350

 caaagagaaa aacactccac aatcaaaaga ttacagaatg tggaaaccac 2400

 tagtctgatc tcatggtatc tttatttaag ctaaatttcc atggaaatta 2450

 gtaatctttt gcttgaaaaa tgtgtcctaa agttgaactt tttacagatt 2500

 gaatcttctt agaccctcgc ccaatgctct aaattaagaa cctaatactt 2550

 aatattttta ttttacttct ccccttttag aaataaactt ttaaataaaa 2600

 gcaaagcact tagctgagtt ttaaacactt acatatcacc tattggagaa 2650

 attttttttt aaaaatattt ggagcagtcc tgttttcata caaatttaag 2700

 taagaggtat ttttcttata catatttata tgtagtgtgc taattttctt 2750

 tttttatacc tgtgtccctg tagtaaaact gctgtaatat aaatacatgt 2800

 tttgttaaaa gataacattt ctttggcatt tcttttaaag gcagttactg 2850

 catttctgca tttgtacagt atgtgtcttg gccattttag atattctttc 2900

 tttaacaata ccaaaggtaa ttagactatt ttaaagacta attgcttgac 2950

 agtttctagg gtattttgtg ttttagaagc aaaaaaagaa aaaaaaatag 3000

 gtcaaaccag taaacctcat tttttttcaa actaataatt tggggaaata 3050

 aaaactattg tttannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 3100

 nnnnnaagtt aaaattccat accttgtatg tcaggtttgc taagtgtaat 3150

 gtagtttttt ttaaggctca aataccatac ctcagaaaat gaggtttact 3200

 atggaaatac tgaaacagtc tttgcagctg tgtgacaagt cactctacta 3250

 catactgatt tggagacctc cgctaaatag ttttatcact gcagactaaa 3300

 atgtgggact tgtatcttct ttgtttttaa tgcacacaca tacatgttct 3350

 gtgcatgtat gtggttactg tgtatatgtg tatgagtgtt gtatatgcat 3400

 gtgtgagtgt gtgtctgtat gtgtgtacaa ctaaagaagc tgcagaaact 3450

 ttgtaatact ttgtgaaaag gattatatta taaaggtttg tactgtctga 3500

 gtgcacagct actggaataa atttagggaa tctcaggaac aagcatataa 3550

 tttgtccaag atttatttct tctcagaagt gtaagtgcag tttttaattc 3600

 tgtatattat ttaatatttt accaataaaa taaacttctg acatacagaa 3650

 gtcctaggtc tttactctta agtttgacct tctacagagt cctagagcat 3700

 ggagacaatg cagccagttc tttgtttata ctaacaaggt ttggtccagt 3750

 tcctaataaa ttcttaattt gtatctgaga tgtcagcttg gcctttactg 3800

 tctatatttg tatgaacatt ttgatcac 3828

<210> 4866
<211> 24
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3065-3105
<223> Unknown amino acid

<400> 4866
 Val Lys Leu Lys Phe Val Tyr Met Lys Val Ile Leu Asp Ile Phe
   1               5                  10                  15

 Leu Ile Leu Gln Phe Leu Gln Asn Asn
                  20

<210> 4867
<211> 4644
<212> DNA
<213> Homo sapien

<400> 4867
 agccaagccc agcagagtgg ccccactggc cagccgagcc agcccccagg 50

 cacagccacc acgccactgg agggtgacgg cctctccgcg cccaccgagg 100

 ttggcgacag ccccctgcag gcccaggctt tgggagaggc aggagtggcc 150

 acaggaagtg aggctcagag cagcccgcaa ttccaggacc acacggaagg 200

 ggaggaccag gacgcttcca tcccctctgg gggcagaggc ctgtcccagg 250

 aggggaccgg tccccccacc tctgctggtg aaggccattc taggactgaa 300

 gatgctgccc aggagctcct gttgcctgag tcaaaaggag gcagctctga 350

 gcccgggaca gaactgcaga ccaccgagca acaggcaggg gcctcagcct 400

 ctatggcagt tgatgctgta gctgagccag ccaatgcagt taaaggggcc 450

 gggaaggaaa tgaaagagaa gacccagaga atgaaacagc caccagcaac 500

 cactcctcct ttcaaaacac actgccagga agctgagacc aagaccaagg 550

 acgagatggc tgctgctgaa gaaaaagtcg gtaagaatga acaaggggag 600

 cctgaagacc tcaagaagcc agaggggaag aacagaagtg cagctgctgt 650

 gaaaaacgag aaggagcaaa aaaaccagga agcagatgtc caggaagtga 700

 aggcaagcac gctgagcccg ggtggaggag tcaccgtgtt cttccacgcc 750

 atcatctctc ttcatttccc attcaatcct gacctccata aagtcttcat 800

 cagaggagga gaagaatttg gggagtcaaa atgggacagc aatatctgtg 850

 agctgcacta caccagagac ttgggtcatg accgcgttct tgttgaaggc 900

 attgtctgca tttccaagaa gcacctagat aaatacattc cttacaagta 950

 cgtcatttat aatggggaat cttttgagta tgagttcatt tacaagcacc 1000

 agcagaagaa gggcgagtac gtcaaccgct gtctgttcat aaaatcttca 1050

 cttctgggct caggagactg gcatcagtac tatgacatag tttatatgaa 1100

 gcctcatggg agactccaga aagtcatgaa ccacatcaca gacgggccga 1150

 ggaaggacct ggtgaagggg aagcagattg ccgctgcgct catgctggac 1200

 agcaccttca gcatcctgca gacctgggac accatcaacc tgaacagctt 1250

 cttcacccag ttcgagcagt tttgctttgt cctgcaacag cctatgattt 1300

 atgaaggaca ggcacagctg tggaccgatt tgcagtacag ggagaaagag 1350

 gtgaagagat acctgtggca acatctgaaa aaacacgtgg taccattgcc 1400

 ggacggaaaa agcacggact ttttgcctgt ggactgccca gtgaggagta 1450

 aactgaaaac aggcctgatt gtcctttttg tagtggaaaa aattgagctt 1500

 ttattagaag gcagcctgga ctggttgtgt cacctcctaa cctcagatgc 1550

 cagctcacca gatgagtttc accgtgacct aagccacatc cttgggatac 1600

 ctcagagctg gcggctgtac ctggtgaacc tgtgccaaag atgcatggac 1650

 acaaggacgt acacctggct gggcgccctg cctgtcctgc actgctgtat 1700

 ggagctggcc ccgcggcaca aggatgcctg gagacagcct gaggacacct 1750

 gggccgctct ggagggactc tccttctcac cgttccggga acaaatgcta 1800

 gatacgagtt ccctacttca gtttatgaga gagaagcagc atttgctgag 1850

 catagacgag cctctcttcc ggtcctggtt tagtctgcta cctctgagtc 1900

 acctggttat gtatatggaa aacttcattg agcacctggg tcgttttcct 1950

 gctcatatcc tggactgtct ttcagggatt tactaccggc ttccgggact 2000

 tgagcaagtc ttgaatacgc aggatgttca ggatgttcag aacgttcaga 2050

 acattttaga aatgctgttg cgactcctgg acacttaccg ggacaagatt 2100

 cccgaggagg ccttgtcacc atcctacctg actgtgtgtc tgaaactgca 2150

 tgaagccatc tgcagcagca caaagctact taagttttac gagctgccag 2200

 ccttatctgc cgagattgtc tgcagaatga ttagacttct atctctggtg 2250

 gattctgcag gacagagaga tgaaactgga aataattcag tccaaacagt 2300

 cttccaaggg acccttgctg ctacgaaaag gtggctccga gaagttttta 2350

 caaagaacat gctcacatct tcaggtgcct cattcacata cgtcaaggaa 2400

 attgaggtct ggaggcggct ggtggaaatc caattccccg cggagcatgg 2450

 ctggaaggag tcgttgctgg gagacatgga atggaggctc acaaaggagg 2500

 aacccctctc ccagatcact gcctactgca atagttgctg ggacaccaaa 2550

 ggcttagagg acagtgtggc caagaccttc gagaaatgca tcattgaagc 2600

 cgtgagctca gcctgccagt ctcagaccag tatccttcag gggttctctt 2650

 actctgattt gcggaaattt ggcatcgtct tgtctgctgt gatcactaag 2700

 tcctggccta ggaccgcgga caacttcgat gacattttaa agcatctgct 2750

 cacgttggca gatgtcaagc acgtcttcag attgtgtgga accgacgaga 2800

 aaatactagc aaatgtcaca gaggatgcca agaggctgat agctgttgcc 2850

 gactctgtgt tgacgaaagt tgttggtgac ctcctaagtg gcacgatttt 2900

 agttggacaa ctggagctga ttataaagca caagaatcag tttcttgaca 2950

 tctggcaact gagggaaaaa agtctttcac cccaggatga aaaatgtgct 3000

 gtggaggaag cactggattg gagaagggag gaactgttac ttctaaagaa 3050

 agagaaaaga tgtgttgata gtctcctgaa gatgtgtggg aacgtgaaac 3100

 atctgataca agtggacttt ggagtgcttg cagtaagaca ctcacaagac 3150

 ctcagcagta aaagattaaa tgacaccatg acagtgagac tgtccacctc 3200

 ctcgaactcg cagagggcaa cgcattacca cctgagctcc caggtccaag 3250

 aaatggctgg gaagatagac ttgctcagag acagccacat cttccagctc 3300

 ttctggcggg aagccgcaga gccgctgagt gagcctaagg aggaccagga 3350

 agccgcagag ttgctgagtg agcccgaaga agaatcagaa aggcacatcc 3400

 ttgagcttca agaggtgtat gactatttgt atcagccttc ttacagaaag 3450

 ttcattaagt tgcaccagga tctaaagtca ggagaggtca cccttgcaga 3500

 gattgatgtc atcttcaagg actttgtgaa taaatacacg gacctggatt 3550

 cagaacttaa gatcatgtgc accgtggacc accagggcca aagagattgg 3600

 atcaaggacc gagtggaaca gatcaaggaa taccatcacc tgcaccaggc 3650

 tgtccacgca gccaaggtca tcttgcaggt caaagagagc ctgggactga 3700

 acggtgactt cagtgttctc aacactttac taaattttac tgataacttc 3750

 gacgactttc gccgtgaaac actggaccag atcaaccagg agctcatcca 3800

 ggccaaaaag ctgctccagg acatcagcga ggcccggtgc aaggggctgc 3850

 aggctctgtc cctgagaaag gagttcatct gctgggtccg ggaggctctt 3900

 ggaggcatca atgagctgaa ggtgtttgtg gacctggcct ccatctcagc 3950

 gggggagaat gacattgatg tggaccgggt ggcctgcttc catgacgctg 4000

 tgcagggcta cgcatccctg ctatttaagc tggaccccag cgtggacttc 4050

 agtgcattca tgaagcatct gaaaaagctg tggaaggctc tggataagga 4100

 ccagtacctg cccaggaaac tggtgagtct tattctgtct ctaatgcaga 4150

 ttttgttgaa tagagcattg cttagcaacg ttagggcagt gactgtggaa 4200

 atggtggcac acctgtgtgg taggtttgta cacagccgtt ttcaatgata 4250

 tttaaaaagc ttttcttcat aaatggaaat tcaccatctt gttacctaga 4300

 aagcaggata caaaattaca tgacacatag taatctctaa ggtgcaaaac 4350

 acacgtggaa aaaagacaga agggaaatat gctgaaacgt tgccaggagt 4400

 tttctctgaa tggttgtaat tgtcatttta ttctgttact ttttgttatt 4450

 ttctataatt gatagaattt tttatcagaa aaaagtaaac atttaaaatt 4500

 agccaggcat ggtggtgtgc gcctgtaatc ccagctactc tggaggctga 4550

 gacagaattg cttgaacccg ggaggcagag atagcagtga actgagatca 4600

 caccactgta ctccagcctg agtgacaaag tgagactctg tctc 4644

<210> 4868
<211> 1415
<212> PRT
<213> Homo sapien

<400> 4868
 Ser Gln Ala Gln Gln Ser Gly Pro Thr Gly Gln Pro Ser Gln Pro
   1               5                  10                  15

 Pro Gly Thr Ala Thr Thr Pro Leu Glu Gly Asp Gly Leu Ser Ala
                  20                  25                  30

 Pro Thr Glu Val Gly Asp Ser Pro Leu Gln Ala Gln Ala Leu Gly
                  35                  40                  45

 Glu Ala Gly Val Ala Thr Gly Ser Glu Ala Gln Ser Ser Pro Gln
                  50                  55                  60

 Phe Gln Asp His Thr Glu Gly Glu Asp Gln Asp Ala Ser Ile Pro
                  65                  70                  75

 Ser Gly Gly Arg Gly Leu Ser Gln Glu Gly Thr Gly Pro Pro Thr
                  80                  85                  90

 Ser Ala Gly Glu Gly His Ser Arg Thr Glu Asp Ala Ala Gln Glu
                  95                 100                 105

 Leu Leu Leu Pro Glu Ser Lys Gly Gly Ser Ser Glu Pro Gly Thr
                 110                 115                 120

 Glu Leu Gln Thr Thr Glu Gln Gln Ala Gly Ala Ser Ala Ser Met
                 125                 130                 135

 Ala Val Asp Ala Val Ala Glu Pro Ala Asn Ala Val Lys Gly Ala
                 140                 145                 150

 Gly Lys Glu Met Lys Glu Lys Thr Gln Arg Met Lys Gln Pro Pro
                 155                 160                 165

 Ala Thr Thr Pro Pro Phe Lys Thr His Cys Gln Glu Ala Glu Thr
                 170                 175                 180

 Lys Thr Lys Asp Glu Met Ala Ala Ala Glu Glu Lys Val Gly Lys
                 185                 190                 195

 Asn Glu Gln Gly Glu Pro Glu Asp Leu Lys Lys Pro Glu Gly Lys
                 200                 205                 210

 Asn Arg Ser Ala Ala Ala Val Lys Asn Glu Lys Glu Gln Lys Asn
                 215                 220                 225

 Gln Glu Ala Asp Val Gln Glu Val Lys Ala Ser Thr Leu Ser Pro
                 230                 235                 240

 Gly Gly Gly Val Thr Val Phe Phe His Ala Ile Ile Ser Leu His
                 245                 250                 255

 Phe Pro Phe Asn Pro Asp Leu His Lys Val Phe Ile Arg Gly Gly
                 260                 265                 270

 Glu Glu Phe Gly Glu Ser Lys Trp Asp Ser Asn Ile Cys Glu Leu
                 275                 280                 285

 His Tyr Thr Arg Asp Leu Gly His Asp Arg Val Leu Val Glu Gly
                 290                 295                 300

 Ile Val Cys Ile Ser Lys Lys His Leu Asp Lys Tyr Ile Pro Tyr
                 305                 310                 315

 Lys Tyr Val Ile Tyr Asn Gly Glu Ser Phe Glu Tyr Glu Phe Ile
                 320                 325                 330

 Tyr Lys His Gln Gln Lys Lys Gly Glu Tyr Val Asn Arg Cys Leu
                 335                 340                 345

 Phe Ile Lys Ser Ser Leu Leu Gly Ser Gly Asp Trp His Gln Tyr
                 350                 355                 360

 Tyr Asp Ile Val Tyr Met Lys Pro His Gly Arg Leu Gln Lys Val
                 365                 370                 375

 Met Asn His Ile Thr Asp Gly Pro Arg Lys Asp Leu Val Lys Gly
                 380                 385                 390

 Lys Gln Ile Ala Ala Ala Leu Met Leu Asp Ser Thr Phe Ser Ile
                 395                 400                 405

 Leu Gln Thr Trp Asp Thr Ile Asn Leu Asn Ser Phe Phe Thr Gln
                 410                 415                 420

 Phe Glu Gln Phe Cys Phe Val Leu Gln Gln Pro Met Ile Tyr Glu
                 425                 430                 435

 Gly Gln Ala Gln Leu Trp Thr Asp Leu Gln Tyr Arg Glu Lys Glu
                 440                 445                 450

 Val Lys Arg Tyr Leu Trp Gln His Leu Lys Lys His Val Val Pro
                 455                 460                 465

 Leu Pro Asp Gly Lys Ser Thr Asp Phe Leu Pro Val Asp Cys Pro
                 470                 475                 480

 Val Arg Ser Lys Leu Lys Thr Gly Leu Ile Val Leu Phe Val Val
                 485                 490                 495

 Glu Lys Ile Glu Leu Leu Leu Glu Gly Ser Leu Asp Trp Leu Cys
                 500                 505                 510

 His Leu Leu Thr Ser Asp Ala Ser Ser Pro Asp Glu Phe His Arg
                 515                 520                 525

 Asp Leu Ser His Ile Leu Gly Ile Pro Gln Ser Trp Arg Leu Tyr
                 530                 535                 540

 Leu Val Asn Leu Cys Gln Arg Cys Met Asp Thr Arg Thr Tyr Thr
                 545                 550                 555

 Trp Leu Gly Ala Leu Pro Val Leu His Cys Cys Met Glu Leu Ala
                 560                 565                 570

 Pro Arg His Lys Asp Ala Trp Arg Gln Pro Glu Asp Thr Trp Ala
                 575                 580                 585

 Ala Leu Glu Gly Leu Ser Phe Ser Pro Phe Arg Glu Gln Met Leu
                 590                 595                 600

 Asp Thr Ser Ser Leu Leu Gln Phe Met Arg Glu Lys Gln His Leu
                 605                 610                 615

 Leu Ser Ile Asp Glu Pro Leu Phe Arg Ser Trp Phe Ser Leu Leu
                 620                 625                 630

 Pro Leu Ser His Leu Val Met Tyr Met Glu Asn Phe Ile Glu His
                 635                 640                 645

 Leu Gly Arg Phe Pro Ala His Ile Leu Asp Cys Leu Ser Gly Ile
                 650                 655                 660

 Tyr Tyr Arg Leu Pro Gly Leu Glu Gln Val Leu Asn Thr Gln Asp
                 665                 670                 675

 Val Gln Asp Val Gln Asn Val Gln Asn Ile Leu Glu Met Leu Leu
                 680                 685                 690

 Arg Leu Leu Asp Thr Tyr Arg Asp Lys Ile Pro Glu Glu Ala Leu
                 695                 700                 705

 Ser Pro Ser Tyr Leu Thr Val Cys Leu Lys Leu His Glu Ala Ile
                 710                 715                 720

 Cys Ser Ser Thr Lys Leu Leu Lys Phe Tyr Glu Leu Pro Ala Leu
                 725                 730                 735

 Ser Ala Glu Ile Val Cys Arg Met Ile Arg Leu Leu Ser Leu Val
                 740                 745                 750

 Asp Ser Ala Gly Gln Arg Asp Glu Thr Gly Asn Asn Ser Val Gln
                 755                 760                 765

 Thr Val Phe Gln Gly Thr Leu Ala Ala Thr Lys Arg Trp Leu Arg
                 770                 775                 780

 Glu Val Phe Thr Lys Asn Met Leu Thr Ser Ser Gly Ala Ser Phe
                 785                 790                 795

 Thr Tyr Val Lys Glu Ile Glu Val Trp Arg Arg Leu Val Glu Ile
                 800                 805                 810

 Gln Phe Pro Ala Glu His Gly Trp Lys Glu Ser Leu Leu Gly Asp
                 815                 820                 825

 Met Glu Trp Arg Leu Thr Lys Glu Glu Pro Leu Ser Gln Ile Thr
                 830                 835                 840

 Ala Tyr Cys Asn Ser Cys Trp Asp Thr Lys Gly Leu Glu Asp Ser
                 845                 850                 855

 Val Ala Lys Thr Phe Glu Lys Cys Ile Ile Glu Ala Val Ser Ser
                 860                 865                 870

 Ala Cys Gln Ser Gln Thr Ser Ile Leu Gln Gly Phe Ser Tyr Ser
                 875                 880                 885

 Asp Leu Arg Lys Phe Gly Ile Val Leu Ser Ala Val Ile Thr Lys
                 890                 895                 900

 Ser Trp Pro Arg Thr Ala Asp Asn Phe Asp Asp Ile Leu Lys His
                 905                 910                 915

 Leu Leu Thr Leu Ala Asp Val Lys His Val Phe Arg Leu Cys Gly
                 920                 925                 930

 Thr Asp Glu Lys Ile Leu Ala Asn Val Thr Glu Asp Ala Lys Arg
                 935                 940                 945

 Leu Ile Ala Val Ala Asp Ser Val Leu Thr Lys Val Val Gly Asp
                 950                 955                 960

 Leu Leu Ser Gly Thr Ile Leu Val Gly Gln Leu Glu Leu Ile Ile
                 965                 970                 975

 Lys His Lys Asn Gln Phe Leu Asp Ile Trp Gln Leu Arg Glu Lys
                 980                 985                 990

 Ser Leu Ser Pro Gln Asp Glu Lys Cys Ala Val Glu Glu Ala Leu
                 995                1000                1005

 Asp Trp Arg Arg Glu Glu Leu Leu Leu Leu Lys Lys Glu Lys Arg
                1010                1015                1020

 Cys Val Asp Ser Leu Leu Lys Met Cys Gly Asn Val Lys His Leu
                1025                1030                1035

 Ile Gln Val Asp Phe Gly Val Leu Ala Val Arg His Ser Gln Asp
                1040                1045                1050

 Leu Ser Ser Lys Arg Leu Asn Asp Thr Met Thr Val Arg Leu Ser
                1055                1060                1065

 Thr Ser Ser Asn Ser Gln Arg Ala Thr His Tyr His Leu Ser Ser
                1070                1075                1080

 Gln Val Gln Glu Met Ala Gly Lys Ile Asp Leu Leu Arg Asp Ser
                1085                1090                1095

 His Ile Phe Gln Leu Phe Trp Arg Glu Ala Ala Glu Pro Leu Ser
                1100                1105                1110

 Glu Pro Lys Glu Asp Gln Glu Ala Ala Glu Leu Leu Ser Glu Pro
                1115                1120                1125

 Glu Glu Glu Ser Glu Arg His Ile Leu Glu Leu Gln Glu Val Tyr
                1130                1135                1140

 Asp Tyr Leu Tyr Gln Pro Ser Tyr Arg Lys Phe Ile Lys Leu His
                1145                1150                1155

 Gln Asp Leu Lys Ser Gly Glu Val Thr Leu Ala Glu Ile Asp Val
                1160                1165                1170

 Ile Phe Lys Asp Phe Val Asn Lys Tyr Thr Asp Leu Asp Ser Glu
                1175                1180                1185

 Leu Lys Ile Met Cys Thr Val Asp His Gln Gly Gln Arg Asp Trp
                1190                1195                1200

 Ile Lys Asp Arg Val Glu Gln Ile Lys Glu Tyr His His Leu His
                1205                1210                1215

 Gln Ala Val His Ala Ala Lys Val Ile Leu Gln Val Lys Glu Ser
                1220                1225                1230

 Leu Gly Leu Asn Gly Asp Phe Ser Val Leu Asn Thr Leu Leu Asn
                1235                1240                1245

 Phe Thr Asp Asn Phe Asp Asp Phe Arg Arg Glu Thr Leu Asp Gln
                1250                1255                1260

 Ile Asn Gln Glu Leu Ile Gln Ala Lys Lys Leu Leu Gln Asp Ile
                1265                1270                1275

 Ser Glu Ala Arg Cys Lys Gly Leu Gln Ala Leu Ser Leu Arg Lys
                1280                1285                1290

 Glu Phe Ile Cys Trp Val Arg Glu Ala Leu Gly Gly Ile Asn Glu
                1295                1300                1305

 Leu Lys Val Phe Val Asp Leu Ala Ser Ile Ser Ala Gly Glu Asn
                1310                1315                1320

 Asp Ile Asp Val Asp Arg Val Ala Cys Phe His Asp Ala Val Gln
                1325                1330                1335

 Gly Tyr Ala Ser Leu Leu Phe Lys Leu Asp Pro Ser Val Asp Phe
                1340                1345                1350

 Ser Ala Phe Met Lys His Leu Lys Lys Leu Trp Lys Ala Leu Asp
                1355                1360                1365

 Lys Asp Gln Tyr Leu Pro Arg Lys Leu Val Ser Leu Ile Leu Ser
                1370                1375                1380

 Leu Met Gln Ile Leu Leu Asn Arg Ala Leu Leu Ser Asn Val Arg
                1385                1390                1395

 Ala Val Thr Val Glu Met Val Ala His Leu Cys Gly Arg Phe Val
                1400                1405                1410

 His Ser Arg Phe Gln
                1415

<210> 4869
<211> 1958
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 185-207, 366-424
<223> Unknown base

<400> 4869
 gcacaagtgg cagaaataat ttcctctggg ctgtaatatg gctaatatcc 50

 aggttgatca gatactaagc taaaaccaga tcaaccttgc ctgggaaggg 100

 acgcaaccta gggatggaga gcaacccagg cagagaggga gaaagaggct 150

 gacacaaatt agccaagagg ggaccccctg aactnnnnnn nnnnnnnnnn 200

 nnnnnnngga aagtgagaaa agccagcaag ccagcaattg tatggtaaga 250

 ataaagctag agaaattaat gttgccagta ctgtgaccct atttttacca 300

 cttctaggct gatgtgggct gggaaatggg ttatgcttag aaatgtggag 350

 cctgccaagt gtggtnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnngagttc agcttttatt cacatttttt 450

 ccccgaagtg atttattctt caaagtagac agttatgttc tatagagtgt 500

 tttgtttttt ctttaagaaa ataatttaca taaacagaga ttatggtaaa 550

 cattttaaat cttaggctgt tggttaaatt taatggttta agcactgttg 600

 ggttctcttt aattaatatt tgcagaagga gaacatatgt gtttcactga 650

 tatgtatggt ccagaaaaat tacttaattc tcaaaaatat gttgcattct 700

 catattgtgt tagggaaaat tccataagta gtctattttt tttttctttt 750

 gctgactgtt aacatccaaa cacctgaatg aaaactgact catttctgta 800

 ttggtgttta aaaatattga tttgcagatg ttcacagaac acttgcattt 850

 tttgattcac attgctaaat caaatgtaaa ggcaaatatg tatatttaat 900

 aaatgagaag tattttttta ttactgaaat ttattctcaa agcaaatgta 950

 ttttgtagat gtttcatttg ggagattttg ctttgcctta aaacatacaa 1000

 aataaacctg tcttgtggtc tgcccacctc aaaacctctg ttaacttgac 1050

 atgtagaagg agttcagaat tctttgataa tgtgtggttt tcacttttgt 1100

 ttggattaaa caaaaataaa attagagtcc atagcacttt gtaaactaat 1150

 gtgaagtttc ttgttgaatc ataaaagcta cctgtatgta ctttataatt 1200

 taatgttctg ttagtaaaaa ttgtcagcat tttatctttt tctcttctca 1250

 ttacatttta gtctccaatc tttcccactc tcagcagtca cagttttgca 1300

 gagcaaaaca tttttagaaa ctgaatatgt gtgagttcta tataaaatga 1350

 atgtgttagt aacatccatc tgctgatcaa ggaggcattg gatctggtac 1400

 tagaaggtga aattgattgt agctatcaaa gcattttatc aatgtaagtc 1450

 aagaaaaaag aagaaaactg tgaacctctg atatttttaa cataaaaact 1500

 gttcccaatg agtgttctct tgctgatttt gtgttaatgt tattgtctat 1550

 gatttttaag ctaatgctaa tataaaatct aaaatttcaa catgatgaca 1600

 acaattcctg tagcctgttt ttaccattag gatgtttttg aaaacagatg 1650

 tcatcttaga aattatattt ttaagtgcaa ataaatcatc ctgacttgaa 1700

 agtcaacaca ttttattttt cattccgtag tatcacagaa tatgctgcat 1750

 ttagatacag gtttaatttg ccagattttc tcaaaattct gtatttttat 1800

 attgctacaa ctggtttact taacatgcaa ttgaattgtt atttaaataa 1850

 attacatttg atggaattgg agtcttattc tggttggtct acatgtggaa 1900

 gcagtacacg acatctgttt tgctggtctt agttgtcaat gtgatataaa 1950

 cttgaatt 1958

<210> 4870
<211> 21
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 185-207, 366-424
<223> Unknown amino acid

<400> 4870
 Thr Ser Gly Arg Asn Asn Phe Leu Trp Ala Val Ile Trp Leu Ile
   1               5                  10                  15

 Ser Arg Leu Ile Arg Tyr
                  20

<210> 4871
<211> 1469
<212> DNA
<213> Homo sapien

<400> 4871
 ctttcttttt ctcttggagc tgagctataa gacaacagga ctgaacaggg 50

 agccaactgt ttctttgaac agtaaatcag gaacaccaat ggaccaaaat 100

 gaacacagtc actggggacc acatgcaaag ggccaatgtg ccagcagatc 150

 tgagctgaga atcatcctgg tgggcaaaac aggaactggc aaaagtgctg 200

 cagggaacag catcctcagg aagcaagcat ttgaatcgaa gctgggttcc 250

 cagaccttga ctaagacttg cagcaaaagt cagggaagct ggggaaatag 300

 agagattgtc attattgaca caccagatat gttttcttgg aaggaccact 350

 gtgaagctct gtacaaagag gtgcagaggt gctacttgct gtctgcacca 400

 ggaccccatg tgctgctcct ggtgactcag ctgggccgct atacctcaca 450

 ggaccagcag gctgcacaga gggtgaagga gatctttgga gaggatgcca 500

 tgggacacac aattgtcctc tttacccaca aggaagacct caatggtggc 550

 tccctgatgg attacatgca cgactcagat aacaaagccc taagcaagct 600

 ggtggcagca tgtggtgggc gaatctgtgc ctttaataac cgtgctgaag 650

 ggagcaatca ggatgaccaa gtgaaggaac taatggactg tattgaggat 700

 ctgttgatgg agaaaaatgg tgatcactat accaatgggt tgtacagcct 750

 aatacagagg tctaaatgtg gacctgtggg atcagatgaa agagtaaagg 800

 aattcaaaca gagccttata aagtacatgg aaactcaaag aagttacaca 850

 gccttggctg aagcaaactg cctaaaagga gccttaatca aaacacaact 900

 gtgtgtttta ttttgtattc agttgtttct cagattgata attctgtggc 950

 tttgcatact gcacagcatg tgcaatttgt tttgttgctt actctttagt 1000

 atgtgcaatt tattctgcag tttgctgttt attataccca aaaagttaat 1050

 gatatttttg agaacagtta ttagactaga acgcaagact cctaggttat 1100

 agttacagat cccagttatt atttactcac tatcatttag tgggtgaatc 1150

 acagtaattt ccctgtaaaa tgtggtacct gaagtcatat ttgagattct 1200

 atgaaatgtt taaatctgaa catcactcca attattaatg aaccaaatca 1250

 tacgataagt tactgtttgc attgaaatat aatatcaaag ccttttgaaa 1300

 tctgtaaaca taaaattcct ctcattttca aatatctaaa gccagtttta 1350

 tgttcctaaa atctcatttt cttctttcta gtactactat ttctactgaa 1400

 tataatgaaa atggcaataa aataatatta cataaactga aaaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaa 1469

<210> 4872
<211> 337
<212> PRT
<213> Homo sapien

<400> 4872
 Met Asp Gln Asn Glu His Ser His Trp Gly Pro His Ala Lys Gly
   1               5                  10                  15

 Gln Cys Ala Ser Arg Ser Glu Leu Arg Ile Ile Leu Val Gly Lys
                  20                  25                  30

 Thr Gly Thr Gly Lys Ser Ala Ala Gly Asn Ser Ile Leu Arg Lys
                  35                  40                  45

 Gln Ala Phe Glu Ser Lys Leu Gly Ser Gln Thr Leu Thr Lys Thr
                  50                  55                  60

 Cys Ser Lys Ser Gln Gly Ser Trp Gly Asn Arg Glu Ile Val Ile
                  65                  70                  75

 Ile Asp Thr Pro Asp Met Phe Ser Trp Lys Asp His Cys Glu Ala
                  80                  85                  90

 Leu Tyr Lys Glu Val Gln Arg Cys Tyr Leu Leu Ser Ala Pro Gly
                  95                 100                 105

 Pro His Val Leu Leu Leu Val Thr Gln Leu Gly Arg Tyr Thr Ser
                 110                 115                 120

 Gln Asp Gln Gln Ala Ala Gln Arg Val Lys Glu Ile Phe Gly Glu
                 125                 130                 135

 Asp Ala Met Gly His Thr Ile Val Leu Phe Thr His Lys Glu Asp
                 140                 145                 150

 Leu Asn Gly Gly Ser Leu Met Asp Tyr Met His Asp Ser Asp Asn
                 155                 160                 165

 Lys Ala Leu Ser Lys Leu Val Ala Ala Cys Gly Gly Arg Ile Cys
                 170                 175                 180

 Ala Phe Asn Asn Arg Ala Glu Gly Ser Asn Gln Asp Asp Gln Val
                 185                 190                 195

 Lys Glu Leu Met Asp Cys Ile Glu Asp Leu Leu Met Glu Lys Asn
                 200                 205                 210

 Gly Asp His Tyr Thr Asn Gly Leu Tyr Ser Leu Ile Gln Arg Ser
                 215                 220                 225

 Lys Cys Gly Pro Val Gly Ser Asp Glu Arg Val Lys Glu Phe Lys
                 230                 235                 240

 Gln Ser Leu Ile Lys Tyr Met Glu Thr Gln Arg Ser Tyr Thr Ala
                 245                 250                 255

 Leu Ala Glu Ala Asn Cys Leu Lys Gly Ala Leu Ile Lys Thr Gln
                 260                 265                 270

 Leu Cys Val Leu Phe Cys Ile Gln Leu Phe Leu Arg Leu Ile Ile
                 275                 280                 285

 Leu Trp Leu Cys Ile Leu His Ser Met Cys Asn Leu Phe Cys Cys
                 290                 295                 300

 Leu Leu Phe Ser Met Cys Asn Leu Phe Cys Ser Leu Leu Phe Ile
                 305                 310                 315

 Ile Pro Lys Lys Leu Met Ile Phe Leu Arg Thr Val Ile Arg Leu
                 320                 325                 330

 Glu Arg Lys Thr Pro Arg Leu
                 335

<210> 4873
<211> 1985
<212> DNA
<213> Homo sapien

<400> 4873
 gcaccgcccc cgcccgcaag aaagatggca gtggcctgat ccgggcccgt 50

 tggcggcgtc actgacgctt cgctccggtc ctcggatccc gagcgcgggg 100

 aggcagaccg actgtgagct gcttgtcccc atcctgcggc cgtcctgggg 150

 acacagagcc ctccgtggtg cccggggatt ggattggagc caggacctca 200

 cttcctcctc tgcccctgcc cctgcccctc ccagcacctg gcccacaccc 250

 tgcagcccgc cccatggtct ggccctgggt ggcgatggcg tccaggtggg 300

 gtcccctcat tggcctggct ccgtgctgcc tctggctcct gggggcagtc 350

 cttctgatgg acgcgtctgc acggcctgcc aaccactcgt ccactcgaga 400

 gagagtagcc aacagggagg agaatgagat cctgccccca gaccacctga 450

 acggggtgaa gctggagatg gacgggcacc tcaatcgcgg cttccaccag 500

 gaggtcttcc taggcaagga cctgggtggc tttgatgagg acgcggagcc 550

 gcggcggagc cggaggaagc tgatggtcat cttttccaag gtggatgtga 600

 acactgaccg gaagatcagt gccaaggaga tgcagcgctg gatcatggag 650

 aagacggccg agcacttcca ggaggccatg gaggagagca agacacactt 700

 ccgcgccgtg gaccctgacg gggacggtca cgtgtcttgg gacgagtata 750

 aggtgaagtt tttggcgagt aaaggccata gcgagaagga ggttgccgac 800

 gccatcaggc tcaacgagga actcaaagtg gacgaggaaa cacaggaagt 850

 cctggagaac ctgaaggacc gctggtacca ggcggacagc ccccctgcag 900

 acctgctgct gacggaggag gagttcctgt cgttcctcca ccccgagcac 950

 agccggggaa tgctcaggtt catggtgaag gagatcgtcc gggacctgga 1000

 ccaggacggt gacaagcagc tctctgtgcc cgagttcatc tccctgcccg 1050

 tgggcaccgt ggagaaccag cagggccagg acattgacga caactgggtg 1100

 aaagacagaa aaaaggagtt tgaggagctc attgactcca accacgacgg 1150

 catcgtgacc gccgaggagc tggagagcta catggacccc atgaacgagt 1200

 acaacgcgct gaacgaggcc aagcagatga tcgccgtcgc cgacgagaac 1250

 cagaaccacc acctggagcc cgaggaggtg ctcaagtaca gcgagttctt 1300

 cacgggcagc aagctggtgg actacgcgcg cagcgtgcac gaggagtttt 1350

 gagcgcccgg ccgcgccccg cgccgccccc cacgcaccac cggggcggcc 1400

 tcgcgggtga ctccgggctc cgtggctgtc ccggacccca cctcttccct 1450

 gccgcccgcc accggccgac cgaccgcggc tgccccagtt gatgagcggc 1500

 gtgtcccctc tgcagcgcgc accccggcgg ggctttggct gtgacgcggt 1550

 cggggcgcgg ggctgggctg tggccccgcg gcgccgcctc ctccctggtc 1600

 cctcgaaatc gtggcatctc acttctgaga acgaaatctc gcttcagtca 1650

 ctctgccgaa ggcgctgacg gcatcgcggc cggaacctct gggcccggcc 1700

 cctcccaggg ccgccgctcc gtgggaaaaa acagctcctc catttccttg 1750

 aaaactgaac gattattaaa aatagattaa acttcgctgg aaatgagtag 1800

 ccaggaagtt caggggaggg tgccgggtcc ttcccgggcc tggcgtgtcg 1850

 gagccaccca ggtcccgcag ctgccgctga gaaaatgcaa atatttgttg 1900

 tgacaagaat cacatacatt tactttaaat atagttgcct tttttggtca 1950

 gcttcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1985

<210> 4874
<211> 362
<212> PRT
<213> Homo sapien

<400> 4874
 Met Val Trp Pro Trp Val Ala Met Ala Ser Arg Trp Gly Pro Leu
   1               5                  10                  15

 Ile Gly Leu Ala Pro Cys Cys Leu Trp Leu Leu Gly Ala Val Leu
                  20                  25                  30

 Leu Met Asp Ala Ser Ala Arg Pro Ala Asn His Ser Ser Thr Arg
                  35                  40                  45

 Glu Arg Val Ala Asn Arg Glu Glu Asn Glu Ile Leu Pro Pro Asp
                  50                  55                  60

 His Leu Asn Gly Val Lys Leu Glu Met Asp Gly His Leu Asn Arg
                  65                  70                  75

 Gly Phe His Gln Glu Val Phe Leu Gly Lys Asp Leu Gly Gly Phe
                  80                  85                  90

 Asp Glu Asp Ala Glu Pro Arg Arg Ser Arg Arg Lys Leu Met Val
                  95                 100                 105

 Ile Phe Ser Lys Val Asp Val Asn Thr Asp Arg Lys Ile Ser Ala
                 110                 115                 120

 Lys Glu Met Gln Arg Trp Ile Met Glu Lys Thr Ala Glu His Phe
                 125                 130                 135

 Gln Glu Ala Met Glu Glu Ser Lys Thr His Phe Arg Ala Val Asp
                 140                 145                 150

 Pro Asp Gly Asp Gly His Val Ser Trp Asp Glu Tyr Lys Val Lys
                 155                 160                 165

 Phe Leu Ala Ser Lys Gly His Ser Glu Lys Glu Val Ala Asp Ala
                 170                 175                 180

 Ile Arg Leu Asn Glu Glu Leu Lys Val Asp Glu Glu Thr Gln Glu
                 185                 190                 195

 Val Leu Glu Asn Leu Lys Asp Arg Trp Tyr Gln Ala Asp Ser Pro
                 200                 205                 210

 Pro Ala Asp Leu Leu Leu Thr Glu Glu Glu Phe Leu Ser Phe Leu
                 215                 220                 225

 His Pro Glu His Ser Arg Gly Met Leu Arg Phe Met Val Lys Glu
                 230                 235                 240

 Ile Val Arg Asp Leu Asp Gln Asp Gly Asp Lys Gln Leu Ser Val
                 245                 250                 255

 Pro Glu Phe Ile Ser Leu Pro Val Gly Thr Val Glu Asn Gln Gln
                 260                 265                 270

 Gly Gln Asp Ile Asp Asp Asn Trp Val Lys Asp Arg Lys Lys Glu
                 275                 280                 285

 Phe Glu Glu Leu Ile Asp Ser Asn His Asp Gly Ile Val Thr Ala
                 290                 295                 300

 Glu Glu Leu Glu Ser Tyr Met Asp Pro Met Asn Glu Tyr Asn Ala
                 305                 310                 315

 Leu Asn Glu Ala Lys Gln Met Ile Ala Val Ala Asp Glu Asn Gln
                 320                 325                 330

 Asn His His Leu Glu Pro Glu Glu Val Leu Lys Tyr Ser Glu Phe
                 335                 340                 345

 Phe Thr Gly Ser Lys Leu Val Asp Tyr Ala Arg Ser Val His Glu
                 350                 355                 360

 Glu Phe


<210> 4875
<211> 672
<212> DNA
<213> Homo sapien

<400> 4875
 catacgcaaa gatagtcacc ataagtcgac catgtttttc accttttagt 50

 caatgttaga agcaaggggt aacttaagtc ctggtgggaa gaccatccat 100

 tgagttcttt gaaagtcaac atttttcagc ccacgatagt gaaatgaaag 150

 taaatataaa tgaataacaa ttctaacaaa aagagttttt tgattcaaat 200

 ccattagttt gaacttttcg agcttattat ccatttcctt aaatcccata 250

 gcttatcaga gttaacatca gagggaggta aaatatttct gtgatattct 300

 ttgtataaaa tctacacttt gaaatggatt agtaacctgt gaacaataca 350

 tattttagtt aacatataaa ttatgtgagc aaagtggttt tcagtgtttt 400

 tttcttattt tagttttgaa cctgtcttaa actcacagac ttgtagaaga 450

 aatctctaat tcagtattta ttaggagttc acttttgccc tattacagcc 500

 ttaattagtg acatcccagt gctgttacag catagcagtg tcttaatatg 550

 taatctaatt gaaataacac atttgtaaaa taattactag aaggtaaact 600

 tacgttaatg tcctgtgtgg tttctacaaa gtgtgtcatt gtagacctct 650

 tggccactag atattttaag at 672

<210> 4876
<211> 21
<212> PRT
<213> Homo sapien

<400> 4876
 Met Ser Cys Val Val Ser Thr Lys Cys Val Ile Val Asp Leu Leu
   1               5                  10                  15

 Ala Thr Arg Tyr Phe Lys
                  20

<210> 4877
<211> 1960
<212> DNA
<213> Homo sapien

<400> 4877
 ggcacgaggg gaagttgccg gcggccgcgc ggcctcccgg gcgggcctac 50

 agccatgtcc cgggacccgg ggtcgggcgg ctgggaggag gccccgcgcg 100

 cagctgccgc gctctgcacc ctgtaccacg aggccggaca gcggctgcgc 150

 cgcctgcagg accagctcgc tgcccgcgac gccctcatcg ctcgcctccg 200

 cgcccgcctg gccgcgctgg agggggacgc cgcgccgtcc ctagtggacg 250

 cgctgctgga gcaggttgcg cgcttccggg agcagctgcg aaggcaggag 300

 ggcggcgccg ccgaggccca gatgcgccag gaaattgaga ggctgactga 350

 gcgactagaa gaaaaagaga gggagatgca gcagctgctg agccagcccc 400

 aacacgagcg agagaaggaa gtcgtcctgc tacggaggag catggcagaa 450

 ggggagcgcg cccgggccgc cagtgacgtc ctgtgccgct ccttggccaa 500

 cgagacccat cagctgcgga ggacgctgac cgccaccgcc cacatgtgtc 550

 agcatctggc caagtgtctg gatgaacgac agcatgcaca aaggaatgtg 600

 ggggagagaa gtcctgacca gtcggaacac acagatgggc acacctctgt 650

 ccagagtgtt attgagaagt tgcaggaaga aaatcgactg ttaaaacaga 700

 aggtgactca cgttgaagac ctcaatgcca agtggcagcg ctacaacgcc 750

 agcagggacg aatacgtgag ggggctccat gcgcagctca gggggctgca 800

 gatcccccac gagcccgagc tgatgaggaa ggagatctcc cggctcaaca 850

 gacagttgga agagaaaata aatgactgtg ccgaagtgaa gcaggagctg 900

 gcggcctcca ggacggcccg ggatgctgcg ttggagcggg tgcagatgct 950

 ggaacagcag attctcgctt acaaggatga cttcatgtca gaaagggccg 1000

 atcgggaacg ggctcaaagt aggattcaag aactggagga aaaggtcgcc 1050

 tctttgctgc accaggtgtc ctggagacag gattctcgag agccagacgc 1100

 cggccggatt cacgctggga gcaaaactgc caagtatttg gccgccgacg 1150

 cattagagct tatggtgcct ggtggctgga ggcctgggac tgggtcccag 1200

 cagccagaac cccctgcaga gggcgggcat cctggcgcgg tccagagagg 1250

 ccagggggac cttcagtgcc ctcactgcct gcagtgcttc agtgacgagc 1300

 aaggggaaga gctcctcagg catgtggccg agtgctgcca gtgaccgaga 1350

 ctcacccgtg cccttgcggc ctcctggccc ggtgcagctg ccctcaggga 1400

 cagggtgggt gctctcagat gccatgggtt gagctctact gagagccaag 1450

 gcccctagaa tagttgcggg gcactctgat cgttcacttt ggtccctttg 1500

 gctatggaac aggctgggtc acagggaact gccagtgagg ctggaggctg 1550

 gaggtggaga tggggtcagg aacatctggc agagggaggt cccagtctgt 1600

 gtctccatca ggcttaagcc agagctatct ggtgctggtg tgccagcccc 1650

 tcccccagcc tgcctagaaa ggggtggctg cctgagggag tcacttgtat 1700

 ggtccccagg gtgggagccc catcctgttc tatggaataa agcgtcgcct 1750

 ctctgcctcg aaccagtcaa atggagtatt gcggctgcac gtcacactag 1800

 ggtggccacc cccgccattg cgagccacat gtctgcactg agaaactgca 1850

 tttcagtagc atttgtcatc cagccggaag ttaaagcaca cttactttat 1900

 tcacctattt ttataataaa cgttcttgct gctgtgactg caaaaaaaaa 1950

 aaaaaaaaaa 1960

<210> 4878
<211> 322
<212> PRT
<213> Homo sapien

<400> 4878
 Met Gln Gln Leu Leu Ser Gln Pro Gln His Glu Arg Glu Lys Glu
   1               5                  10                  15

 Val Val Leu Leu Arg Arg Ser Met Ala Glu Gly Glu Arg Ala Arg
                  20                  25                  30

 Ala Ala Ser Asp Val Leu Cys Arg Ser Leu Ala Asn Glu Thr His
                  35                  40                  45

 Gln Leu Arg Arg Thr Leu Thr Ala Thr Ala His Met Cys Gln His
                  50                  55                  60

 Leu Ala Lys Cys Leu Asp Glu Arg Gln His Ala Gln Arg Asn Val
                  65                  70                  75

 Gly Glu Arg Ser Pro Asp Gln Ser Glu His Thr Asp Gly His Thr
                  80                  85                  90

 Ser Val Gln Ser Val Ile Glu Lys Leu Gln Glu Glu Asn Arg Leu
                  95                 100                 105

 Leu Lys Gln Lys Val Thr His Val Glu Asp Leu Asn Ala Lys Trp
                 110                 115                 120

 Gln Arg Tyr Asn Ala Ser Arg Asp Glu Tyr Val Arg Gly Leu His
                 125                 130                 135

 Ala Gln Leu Arg Gly Leu Gln Ile Pro His Glu Pro Glu Leu Met
                 140                 145                 150

 Arg Lys Glu Ile Ser Arg Leu Asn Arg Gln Leu Glu Glu Lys Ile
                 155                 160                 165

 Asn Asp Cys Ala Glu Val Lys Gln Glu Leu Ala Ala Ser Arg Thr
                 170                 175                 180

 Ala Arg Asp Ala Ala Leu Glu Arg Val Gln Met Leu Glu Gln Gln
                 185                 190                 195

 Ile Leu Ala Tyr Lys Asp Asp Phe Met Ser Glu Arg Ala Asp Arg
                 200                 205                 210

 Glu Arg Ala Gln Ser Arg Ile Gln Glu Leu Glu Glu Lys Val Ala
                 215                 220                 225

 Ser Leu Leu His Gln Val Ser Trp Arg Gln Asp Ser Arg Glu Pro
                 230                 235                 240

 Asp Ala Gly Arg Ile His Ala Gly Ser Lys Thr Ala Lys Tyr Leu
                 245                 250                 255

 Ala Ala Asp Ala Leu Glu Leu Met Val Pro Gly Gly Trp Arg Pro
                 260                 265                 270

 Gly Thr Gly Ser Gln Gln Pro Glu Pro Pro Ala Glu Gly Gly His
                 275                 280                 285

 Pro Gly Ala Val Gln Arg Gly Gln Gly Asp Leu Gln Cys Pro His
                 290                 295                 300

 Cys Leu Gln Cys Phe Ser Asp Glu Gln Gly Glu Glu Leu Leu Arg
                 305                 310                 315

 His Val Ala Glu Cys Cys Gln
                 320

<210> 4879
<211> 1688
<212> DNA
<213> Homo sapien

<400> 4879
 gcccaggctg ctcaatgccc gccgctgccc catcgccttc tccgtgcctc 50

 taccctctct tttctcgggt ttacctcctt cactatgggc aaccttccac 100

 cctccattcc tccttcttct cccttagcct gtgttctcaa aaacttaaaa 150

 cctcttcaac tcacacctga cctaaaacct aagtgtctta ttttcttctg 200

 caacaccgct tggccccaat acaaactcga caatgattcc aaatagccag 250

 aaaacggcac tttcgagttc tccatcctac aagttctaga taattcttgt 300

 cataaaatgg gcaaatggtc tgaggtgcct gacgtccagg cattctttta 350

 cacattggtc cctccctagt ctctgctccc aatgtgactc atcccaaatc 400

 tttcttcttt ctctcctttc tgttccttcg gtctccaccc caagttccga 450

 gtcctctgaa tccttctttt ctatggactc atctgacctc cccccttctc 500

 cccaggctgc tcctcgccag gctgagccag gtcccaattc tcacttagcc 550

 tctgctcccc caccctataa tccttttatc acctcccctc ctcacacctg 600

 gtccagctta cagtttcgtt cctcgactag ctctccccga tctgcccaac 650

 aatttcctgt taaagagatg gctgactatc ctgacttcat cagagcaggc 700

 tggtgcctgg ccttcctgga atgagtgggt gttctgacag gcccccagtt 750

 tgtcccatct gcaccgccaa gaggtctccg ggtggccaga ggagcaaagt 800

 tgccttccaa gtgcctgttg gtgcctggga gaacacagca ggagtgtcgt 850

 gcggcccaca gcgcagtgca tggtgattcc aggcgctgaa caactcccct 900

 tgacccttgg gcctgcatct gactcccggc tgcagaatca gaagctgagt 950

 ccaggcaacc gctcggccac tcccggtcac tcctctctgg acacccagtt 1000

 actaaagtca gcaaagaaga tgcggtaatc accgcctgat ctccacatgg 1050

 tgaacacaac actctcacta acacctcctt gaccagtcag tcttcagcac 1100

 tgggggtgga caggcaggtt ttctgtgttt accagaatcg cacaggctaa 1150

 gcacaaacat ggaaccagag ttccaggtga ggaaacctca ctcgcagaag 1200

 cccaggctgc accccaccag gtgatgcagt gcgcctaggc tgtgggtgct 1250

 aggagccaag tgctagggac tcgtcatgag tgggaatccc cacgttcctg 1300

 tcactgctgt caaacagaag gtaaacagtc ttacgaatgt aattccttag 1350

 gaagacttgt acaaactttt attaggatat ctatttattt aatactgaac 1400

 tttggcctac tttgtgataa gactataaac aaattgagga aatcactatt 1450

 tctcacttct gtatttctca aaaaataatt ttgttacaga gttcaatata 1500

 ctgtgtacta ctgatcttct attgtgaaag caaagcattt catcaaaaca 1550

 aagtatttta aattatgagt gaaaattgtg tatgttaatt ttgcagctgt 1600

 aatattaatc aaactttgtg taattctaat cacaaaatga tgtgccttaa 1650

 atgcccctcc agctgtgggt tggcagtgtc cagacagg 1688

<210> 4880
<211> 81
<212> PRT
<213> Homo sapien

<400> 4880
 Ala Gln Ala Ala Gln Cys Pro Pro Leu Pro His Arg Leu Leu Arg
   1               5                  10                  15

 Ala Ser Thr Leu Ser Phe Leu Gly Phe Thr Ser Phe Thr Met Gly
                  20                  25                  30

 Asn Leu Pro Pro Ser Ile Pro Pro Ser Ser Pro Leu Ala Cys Val
                  35                  40                  45

 Leu Lys Asn Leu Lys Pro Leu Gln Leu Thr Pro Asp Leu Lys Pro
                  50                  55                  60

 Lys Cys Leu Ile Phe Phe Cys Asn Thr Ala Trp Pro Gln Tyr Lys
                  65                  70                  75

 Leu Asp Asn Asp Ser Lys
                  80

<210> 4881
<211> 2463
<212> DNA
<213> Homo sapien

<400> 4881
 gcttggtacc gagctcggat ccactagtaa cggccgccag tgtgctggaa 50

 agggacgcca ccgggcgctg acagacctat ggagagtcag ggtgtgcctc 100

 ccgggcctta tcgggccacc aagctgtgga atgaagttac cacatctttt 150

 cgagcaggaa tgcctctaag aaaacacaga caacacttta aaaaatatgg 200

 caattgtttc acagcaggag aagcagtgga ttggctttat gacctattaa 250

 gaaataatag caattttggt cctgaagtta caaggcaaca gactatccaa 300

 ctgttgagga aatttcttaa gaatcatgta attgaagata tcaaagggag 350

 gtggggatca gaaaatgttg atgataacaa ccagctcttc agatttcctg 400

 caacttcgcc acttaaaact ctaccacgaa ggtatccaga attgagaaaa 450

 aacaacatag agaacttttc caaagataaa gatagcattt ttaaattacg 500

 aaacttatct cgtagaactc ctaaaaggca tggattacat ttatctcagg 550

 aaaatggcga gaaaataaag catgaaataa tcaatgaaga tcaagaaaat 600

 gcaattgata atagagaact aagccaggaa gatgttgaag aagtttggag 650

 atatgttatt ctgatctacc tgcaaaccat tttaggtgtg ccatccctag 700

 aagaagtcat aaatccaaaa caagtaattc cccaatatat aatgtacaac 750

 atggccaata caagtaaacg tggagtagtt atactacaaa acaaatcaga 800

 tgacctccct cactgggtat tatctgccat gaagtgccta gcaaattggc 850

 caagaagcaa tgatatgaat aatccaactt atgttggatt tgaacgagat 900

 gtattcagaa caatcgcaga ttattttcta gatctccctg aacctctact 950

 tacttttgaa tattacgaat tatttgtaaa cattttgggc ttgctgcaac 1000

 ctcatttaga gagggttgcc atcgatgctc tacagttatg ttgtttgtta 1050

 cttcccccac caaatcgtag aaagcttcaa cttttaatgc gtatgatttc 1100

 ccgaatgagt caaaatgttg atatgcccaa acttcatgat gcaatgggta 1150

 cgaggtcact gatgatacat accttttctc gatgtgtgtt atgctgtgct 1200

 gaagaagtgg atcttgatga gcttcttgct ggaagattag tttctttctt 1250

 aatggatcat catcaggaaa ttcttcaagt accctcttac ttacagactg 1300

 cagtggaaaa acatcttgac tacttaaaaa agggacatat tgaaaatcct 1350

 ggagatggac tatttgctcc tttgccaact tactcatact gtaagcagat 1400

 tagtgctcag gagtttgatg agcaaaaagt ttctacctct caagctgcaa 1450

 ttgcagaact tttagaaaat attattaaaa acaggagttt acctctaaag 1500

 gagaaaagaa aaaaactaaa acagtttcag aaggaatatc ctttgatata 1550

 tcagaaaaga tttccaacca cggagagtga agcagcactt tttggtgaca 1600

 aacctacaat caagcaacca atgctgattt taagaaaacc aaagttccgt 1650

 agtctaagat aactaactga attaaaaatt atgtaatact tgtggaactt 1700

 tgataaatga agccatatct gagaatgtag ctactcaaaa ggaagtctgt 1750

 cattaataag gtatttctaa ataaacacat tatgtaagga agtgccaaaa 1800

 tagttatcaa tgtgagactc ttaggaaact aactagatct caattgagag 1850

 cacataacaa tagatgatac caaatacttt ttgtttttaa cacagctatc 1900

 cagtaaggct atcatgatgt gtgctaaaat tttatttact tgaattttga 1950

 aaactgagct gtgttaggga ttaaactata attctgttct taaaagaaaa 2000

 tttatctgca aatgtgcaag ttctgagata ttagctaatg aattagttgt 2050

 ttggggttac ttctttgttt ctaagtataa gaatgtgaag aatatttgaa 2100

 aactcaatga aataattctc agctgccaaa tgttgcactc ttttatatat 2150

 tctttttcca cttttgatct atttatatat atgtatgtgt ttttaaaata 2200

 tgtgtatatt ttatcagatt tggttttgcc ttaaatatta tccccaattg 2250

 cttcagtcat tcatttgttc agtatatata ttttgaattc tagttttcat 2300

 aatctattag aagatgggga tataaaagaa gtataaggca atcatatatt 2350

 cattcaaaag atatttattt agcaactgct atgtgccttt cgttgttcca 2400

 gatatgcaga gacaatgata aataaaacat ataatctctt ccaaaaaaaa 2450

 aaaaaaaaaa aaa 2463

<210> 4882
<211> 527
<212> PRT
<213> Homo sapien

<400> 4882
 Met Glu Ser Gln Gly Val Pro Pro Gly Pro Tyr Arg Ala Thr Lys
   1               5                  10                  15

 Leu Trp Asn Glu Val Thr Thr Ser Phe Arg Ala Gly Met Pro Leu
                  20                  25                  30

 Arg Lys His Arg Gln His Phe Lys Lys Tyr Gly Asn Cys Phe Thr
                  35                  40                  45

 Ala Gly Glu Ala Val Asp Trp Leu Tyr Asp Leu Leu Arg Asn Asn
                  50                  55                  60

 Ser Asn Phe Gly Pro Glu Val Thr Arg Gln Gln Thr Ile Gln Leu
                  65                  70                  75

 Leu Arg Lys Phe Leu Lys Asn His Val Ile Glu Asp Ile Lys Gly
                  80                  85                  90

 Arg Trp Gly Ser Glu Asn Val Asp Asp Asn Asn Gln Leu Phe Arg
                  95                 100                 105

 Phe Pro Ala Thr Ser Pro Leu Lys Thr Leu Pro Arg Arg Tyr Pro
                 110                 115                 120

 Glu Leu Arg Lys Asn Asn Ile Glu Asn Phe Ser Lys Asp Lys Asp
                 125                 130                 135

 Ser Ile Phe Lys Leu Arg Asn Leu Ser Arg Arg Thr Pro Lys Arg
                 140                 145                 150

 His Gly Leu His Leu Ser Gln Glu Asn Gly Glu Lys Ile Lys His
                 155                 160                 165

 Glu Ile Ile Asn Glu Asp Gln Glu Asn Ala Ile Asp Asn Arg Glu
                 170                 175                 180

 Leu Ser Gln Glu Asp Val Glu Glu Val Trp Arg Tyr Val Ile Leu
                 185                 190                 195

 Ile Tyr Leu Gln Thr Ile Leu Gly Val Pro Ser Leu Glu Glu Val
                 200                 205                 210

 Ile Asn Pro Lys Gln Val Ile Pro Gln Tyr Ile Met Tyr Asn Met
                 215                 220                 225

 Ala Asn Thr Ser Lys Arg Gly Val Val Ile Leu Gln Asn Lys Ser
                 230                 235                 240

 Asp Asp Leu Pro His Trp Val Leu Ser Ala Met Lys Cys Leu Ala
                 245                 250                 255

 Asn Trp Pro Arg Ser Asn Asp Met Asn Asn Pro Thr Tyr Val Gly
                 260                 265                 270

 Phe Glu Arg Asp Val Phe Arg Thr Ile Ala Asp Tyr Phe Leu Asp
                 275                 280                 285

 Leu Pro Glu Pro Leu Leu Thr Phe Glu Tyr Tyr Glu Leu Phe Val
                 290                 295                 300

 Asn Ile Leu Gly Leu Leu Gln Pro His Leu Glu Arg Val Ala Ile
                 305                 310                 315

 Asp Ala Leu Gln Leu Cys Cys Leu Leu Leu Pro Pro Pro Asn Arg
                 320                 325                 330

 Arg Lys Leu Gln Leu Leu Met Arg Met Ile Ser Arg Met Ser Gln
                 335                 340                 345

 Asn Val Asp Met Pro Lys Leu His Asp Ala Met Gly Thr Arg Ser
                 350                 355                 360

 Leu Met Ile His Thr Phe Ser Arg Cys Val Leu Cys Cys Ala Glu
                 365                 370                 375

 Glu Val Asp Leu Asp Glu Leu Leu Ala Gly Arg Leu Val Ser Phe
                 380                 385                 390

 Leu Met Asp His His Gln Glu Ile Leu Gln Val Pro Ser Tyr Leu
                 395                 400                 405

 Gln Thr Ala Val Glu Lys His Leu Asp Tyr Leu Lys Lys Gly His
                 410                 415                 420

 Ile Glu Asn Pro Gly Asp Gly Leu Phe Ala Pro Leu Pro Thr Tyr
                 425                 430                 435

 Ser Tyr Cys Lys Gln Ile Ser Ala Gln Glu Phe Asp Glu Gln Lys
                 440                 445                 450

 Val Ser Thr Ser Gln Ala Ala Ile Ala Glu Leu Leu Glu Asn Ile
                 455                 460                 465

 Ile Lys Asn Arg Ser Leu Pro Leu Lys Glu Lys Arg Lys Lys Leu
                 470                 475                 480

 Lys Gln Phe Gln Lys Glu Tyr Pro Leu Ile Tyr Gln Lys Arg Phe
                 485                 490                 495

 Pro Thr Thr Glu Ser Glu Ala Ala Leu Phe Gly Asp Lys Pro Thr
                 500                 505                 510

 Ile Lys Gln Pro Met Leu Ile Leu Arg Lys Pro Lys Phe Arg Ser
                 515                 520                 525

 Leu Arg


<210> 4883
<211> 3463
<212> DNA
<213> Homo sapien

<400> 4883
 ctcttacaac attggctgcc ggcgtgactt tgaccgcttc ccggtgcgtt 50

 accggcagct gaacccaccc ggcgccacgg gactttgacg cgtgctctgc 100

 gcttgccatg agactcctgg gagctgcagc cgtcgcggct ctggggcgcg 150

 gaagggcccc cgcctcccta ggctggcaga ggaagcaggt taattggaag 200

 gcctgccgat ggtcttcatc aggggtgatt cctaatgaaa aaatacgaaa 250

 tattggaatc tcagctcaca ttgattctgg gaaaactaca ttaacagaac 300

 gagtccttta ctacactggc agaattgcaa agatgcatga ggtgaaaggt 350

 aaagatggag ttggtgctgt catggattcc atggaactag agagacaaag 400

 aggaatcact attcagtcag cagccactta caccatgtgg aaagatgtca 450

 atattaacat tatagatact cctgggcatg tggacttcac aatagaagtg 500

 gaaagggccc tgagagtgtt ggatggtgca gtccttgttc tctgtgctgt 550

 tggaggggta cagtgccaga ccatgactgt caatcgtcag atgaagcgct 600

 acaacgttcc gtttctaact tttattaaca aattggaccg aatgggctcc 650

 aacccagcca gggccctgca gcaaatgagg tctaaactaa atcataatgc 700

 agcgtttatg cagataccca tgggtttgga gggtaatttt aaaggtattg 750

 tagatcttat tgaggaacga gccatctatt ttgatggaga ctttggtcag 800

 attgttcgat atggtgagat tccagctgaa ttaagggcgg cggccactga 850

 ccaccggcag gagctaattg aatgtgttgc caattcagat gaacagcttg 900

 gtgagatgtt tctggaagaa aaaatcccct cgatttctga tttaaagcta 950

 gcaattcgaa gagctactct gaaaagatca tttactcctg tatttttggg 1000

 aagcgccttg aagaacaaag gagttcagcc tcttttagat gctgttttag 1050

 aatacctccc aaatccatct gaagtccaga actatgctat tctcaataaa 1100

 gaggatgact caaaagagaa aaccaaaatc ctaatgaact ccagtagaga 1150

 caattcccac ccatttgtag gcctggcttt taaactggag gtaggtcgat 1200

 ttggacaatt aacttatgtt cgcagttatc agggagagct aaagaagggt 1250

 gacaccatct ataacacaag gacaagaaag aaagtacggt tgcaacggct 1300

 ggctcgcatg catgccgaca tgatggagga tgttgaggaa gtatatgccg 1350

 gagacatctg tgcattgttt ggcattgact gtgctagtgg agacacattc 1400

 acagacaaag ccaacagcgg cctttctatg gagtcaattc atgttcctga 1450

 tcctgtcatt tcaatagcaa tgaagccttc taacaagaac gatctggaaa 1500

 aattttcaaa aggtattggc aggtttacaa gagaagatcc cacatttaaa 1550

 gtatactttg acactgagaa caaagagaca gttatatctg gaatgggaga 1600

 attacacctg gaaatctatg ctcagaggct ggaaagagag tatggctgtc 1650

 cttgtatcac aggaaagcca aaagttgcct ttcgagagac cattactgcc 1700

 cctgtcccgt ttgactttac acataaaaaa caatcaggtg gtgcaggcca 1750

 gtatggaaaa gtaataggtg tcctggagcc tctggaccca gaggactaca 1800

 ctaaattgga attttcagat gaaacattcg gatcaaatat tccaaagcag 1850

 tttgtgcctg ctgtagaaaa ggggttttta gatgcctgcg agaagggccc 1900

 tctttctggt cacaagctct ctgggctccg gtttgtcctg caagatggag 1950

 cacaccacat ggttgattct aatgaaatct ctttcatccg agcaggagaa 2000

 ggtgctctta aacaagcctt ggcaaatgca acattatgta ttcttgaacc 2050

 tattatggct gtggaagttg tagctccaaa tgaatttcag ggacaagtaa 2100

 ttgcaggaat taaccgacgc catggggtaa tcactgggca agatggagtt 2150

 gaggactatt ttacactgta tgcagatgtc cctctaaatg atatgtttgg 2200

 ttattccact gaacttaggt catgcacaga gggaaaggga gaatacacaa 2250

 tggagtatag caggtatcag ccatgtttac catccacaca agaagacgtc 2300

 attaataagt atttggaagc tacaggtcaa cttcctgtta aaaaaggaaa 2350

 agccaagaac taactttgct tactgtgagt tgactgactc taattgaatc 2400

 tgcgtggttt tgatactttg atggattcca gtggaataaa ttcaggctgc 2450

 tgaaacaaga aattctgagc ccaggaagcg ggctcttctt tcttcaaaag 2500

 aagcccttct tgttcatatt caggagcttc tgttatattc aaaggtaatt 2550

 ctatgtctat ctcaactcta ttgattggtt ttatagttta ttgaaaatcc 2600

 tcaaataaaa tataattatt actgaaatat gtttaatatt taaggggaaa 2650

 agagactaat ttcagttata cttttaagct tagaatgtat gttcatttcc 2700

 aaattttgta tcataagagt tttcaacata gagaaaagct gaaaaaatgc 2750

 aaagaataac cacatacttt ccatctacct tcctttgtta acgggttgtt 2800

 tatcatataa taatttgttt tgtcatattt gctttcactg tctattatct 2850

 gtttaagtct cataactcta tttttagttt gctgaagact tgaaagtgaa 2900

 tcgcatatat catgacactt cttggagtgt cattaatggg caggcttttc 2950

 tgttgaagag tggattccgt atgttcttca tagagagtgt ttttcagatt 3000

 cttcattggg atattaaaat attagccaaa tttctctctg ttttatatat 3050

 gtctgtttat ttcagtttgt ggtttctgca aatttgtaac tgcctctgtt 3100

 ttaggagtat aagtattact tccttgtggt ctattgtgaa gtaaaaagta 3150

 gacccttgca tatactattc ttgtttgtgt tcatcttaat gtttttgtac 3200

 agctaaatca aatgtaattt atagagttag tttcatcaac ctaatgaatg 3250

 ctagttaaat ttgaattcct tggaatttat cgtatattgt attcactgag 3300

 attatgaagg gacaaatgtt aatcttttgt ttccagaaaa agttgggctt 3350

 tcccaagcag ttctattacc cggttcagaa ttgcttcatc caaaaatcat 3400

 ctgatggtat agatggatcc tagtcctttt cattacctga tggtagaaat 3450

 aaaataattg att 3463

<210> 4884
<211> 751
<212> PRT
<213> Homo sapien

<400> 4884
 Met Arg Leu Leu Gly Ala Ala Ala Val Ala Ala Leu Gly Arg Gly
   1               5                  10                  15

 Arg Ala Pro Ala Ser Leu Gly Trp Gln Arg Lys Gln Val Asn Trp
                  20                  25                  30

 Lys Ala Cys Arg Trp Ser Ser Ser Gly Val Ile Pro Asn Glu Lys
                  35                  40                  45

 Ile Arg Asn Ile Gly Ile Ser Ala His Ile Asp Ser Gly Lys Thr
                  50                  55                  60

 Thr Leu Thr Glu Arg Val Leu Tyr Tyr Thr Gly Arg Ile Ala Lys
                  65                  70                  75

 Met His Glu Val Lys Gly Lys Asp Gly Val Gly Ala Val Met Asp
                  80                  85                  90

 Ser Met Glu Leu Glu Arg Gln Arg Gly Ile Thr Ile Gln Ser Ala
                  95                 100                 105

 Ala Thr Tyr Thr Met Trp Lys Asp Val Asn Ile Asn Ile Ile Asp
                 110                 115                 120

 Thr Pro Gly His Val Asp Phe Thr Ile Glu Val Glu Arg Ala Leu
                 125                 130                 135

 Arg Val Leu Asp Gly Ala Val Leu Val Leu Cys Ala Val Gly Gly
                 140                 145                 150

 Val Gln Cys Gln Thr Met Thr Val Asn Arg Gln Met Lys Arg Tyr
                 155                 160                 165

 Asn Val Pro Phe Leu Thr Phe Ile Asn Lys Leu Asp Arg Met Gly
                 170                 175                 180

 Ser Asn Pro Ala Arg Ala Leu Gln Gln Met Arg Ser Lys Leu Asn
                 185                 190                 195

 His Asn Ala Ala Phe Met Gln Ile Pro Met Gly Leu Glu Gly Asn
                 200                 205                 210

 Phe Lys Gly Ile Val Asp Leu Ile Glu Glu Arg Ala Ile Tyr Phe
                 215                 220                 225

 Asp Gly Asp Phe Gly Gln Ile Val Arg Tyr Gly Glu Ile Pro Ala
                 230                 235                 240

 Glu Leu Arg Ala Ala Ala Thr Asp His Arg Gln Glu Leu Ile Glu
                 245                 250                 255

 Cys Val Ala Asn Ser Asp Glu Gln Leu Gly Glu Met Phe Leu Glu
                 260                 265                 270

 Glu Lys Ile Pro Ser Ile Ser Asp Leu Lys Leu Ala Ile Arg Arg
                 275                 280                 285

 Ala Thr Leu Lys Arg Ser Phe Thr Pro Val Phe Leu Gly Ser Ala
                 290                 295                 300

 Leu Lys Asn Lys Gly Val Gln Pro Leu Leu Asp Ala Val Leu Glu
                 305                 310                 315

 Tyr Leu Pro Asn Pro Ser Glu Val Gln Asn Tyr Ala Ile Leu Asn
                 320                 325                 330

 Lys Glu Asp Asp Ser Lys Glu Lys Thr Lys Ile Leu Met Asn Ser
                 335                 340                 345

 Ser Arg Asp Asn Ser His Pro Phe Val Gly Leu Ala Phe Lys Leu
                 350                 355                 360

 Glu Val Gly Arg Phe Gly Gln Leu Thr Tyr Val Arg Ser Tyr Gln
                 365                 370                 375

 Gly Glu Leu Lys Lys Gly Asp Thr Ile Tyr Asn Thr Arg Thr Arg
                 380                 385                 390

 Lys Lys Val Arg Leu Gln Arg Leu Ala Arg Met His Ala Asp Met
                 395                 400                 405

 Met Glu Asp Val Glu Glu Val Tyr Ala Gly Asp Ile Cys Ala Leu
                 410                 415                 420

 Phe Gly Ile Asp Cys Ala Ser Gly Asp Thr Phe Thr Asp Lys Ala
                 425                 430                 435

 Asn Ser Gly Leu Ser Met Glu Ser Ile His Val Pro Asp Pro Val
                 440                 445                 450

 Ile Ser Ile Ala Met Lys Pro Ser Asn Lys Asn Asp Leu Glu Lys
                 455                 460                 465

 Phe Ser Lys Gly Ile Gly Arg Phe Thr Arg Glu Asp Pro Thr Phe
                 470                 475                 480

 Lys Val Tyr Phe Asp Thr Glu Asn Lys Glu Thr Val Ile Ser Gly
                 485                 490                 495

 Met Gly Glu Leu His Leu Glu Ile Tyr Ala Gln Arg Leu Glu Arg
                 500                 505                 510

 Glu Tyr Gly Cys Pro Cys Ile Thr Gly Lys Pro Lys Val Ala Phe
                 515                 520                 525

 Arg Glu Thr Ile Thr Ala Pro Val Pro Phe Asp Phe Thr His Lys
                 530                 535                 540

 Lys Gln Ser Gly Gly Ala Gly Gln Tyr Gly Lys Val Ile Gly Val
                 545                 550                 555

 Leu Glu Pro Leu Asp Pro Glu Asp Tyr Thr Lys Leu Glu Phe Ser
                 560                 565                 570

 Asp Glu Thr Phe Gly Ser Asn Ile Pro Lys Gln Phe Val Pro Ala
                 575                 580                 585

 Val Glu Lys Gly Phe Leu Asp Ala Cys Glu Lys Gly Pro Leu Ser
                 590                 595                 600

 Gly His Lys Leu Ser Gly Leu Arg Phe Val Leu Gln Asp Gly Ala
                 605                 610                 615

 His His Met Val Asp Ser Asn Glu Ile Ser Phe Ile Arg Ala Gly
                 620                 625                 630

 Glu Gly Ala Leu Lys Gln Ala Leu Ala Asn Ala Thr Leu Cys Ile
                 635                 640                 645

 Leu Glu Pro Ile Met Ala Val Glu Val Val Ala Pro Asn Glu Phe
                 650                 655                 660

 Gln Gly Gln Val Ile Ala Gly Ile Asn Arg Arg His Gly Val Ile
                 665                 670                 675

 Thr Gly Gln Asp Gly Val Glu Asp Tyr Phe Thr Leu Tyr Ala Asp
                 680                 685                 690

 Val Pro Leu Asn Asp Met Phe Gly Tyr Ser Thr Glu Leu Arg Ser
                 695                 700                 705

 Cys Thr Glu Gly Lys Gly Glu Tyr Thr Met Glu Tyr Ser Arg Tyr
                 710                 715                 720

 Gln Pro Cys Leu Pro Ser Thr Gln Glu Asp Val Ile Asn Lys Tyr
                 725                 730                 735

 Leu Glu Ala Thr Gly Gln Leu Pro Val Lys Lys Gly Lys Ala Lys
                 740                 745                 750

 Asn


<210> 4885
<211> 736
<212> DNA
<213> Homo sapien

<400> 4885
 acatgttatg gagaaatggt cataagatct gaacaacaaa agtatgttta 50

 ctacttagca aacatgtctg ttggacaggt tctgctaaca taatgagagt 100

 gcatttgtac attcaggtag ctaagactta acaaatctaa aaattcctta 150

 cttcaaaagt tcagctattt aaagtgtttg gttcacaatt aaaggagatt 200

 gtgttttaaa caatacatac tgtacttttt aaaggttgta ttagcacatg 250

 caaacagttc accttaaaaa aacagaatga gtcataagga gtcagacatg 300

 ccattaatca gctcttaatt atcttccata aaagagggaa ggaaaaaaat 350

 agagataaca cgaatctgtg tataatccaa aaggttctct gtgacttgga 400

 atgaagccag aaaaagaatc tcattttgtt tcacacactg gcacctggta 450

 tggagatcaa cagttgctca aaggaatttt aaataattat aatgtgttaa 500

 tagataatta attgggaatt gattctgcaa ggcaaagtca aacatttgtt 550

 ttataattgt gcagttcttg caagagatca cctatacttt ttttccccca 600

 tcaggtataa tgggtctctc ccaaatggcg atagaggaag gaggaaaagt 650

 aggtttgctt tgtttaaaag acctaaggca aatggggtga agcccagcac 700

 tgtgcatatt gcttgtactc ctcaggctgc aaaggt 736

<210> 4886
<211> 111
<212> PRT
<213> Homo sapien

<400> 4886
 Met Lys Pro Glu Lys Glu Ser His Phe Val Ser His Thr Gly Thr
   1               5                  10                  15

 Trp Tyr Gly Asp Gln Gln Leu Leu Lys Gly Ile Leu Asn Asn Tyr
                  20                  25                  30

 Asn Val Leu Ile Asp Asn Asn Trp Glu Leu Ile Leu Gln Gly Lys
                  35                  40                  45

 Val Lys His Leu Phe Tyr Asn Cys Ala Val Leu Ala Arg Asp His
                  50                  55                  60

 Leu Tyr Phe Phe Ser Pro Ile Arg Tyr Asn Gly Ser Leu Pro Asn
                  65                  70                  75

 Gly Asp Arg Gly Arg Arg Lys Ser Arg Phe Ala Leu Phe Lys Arg
                  80                  85                  90

 Pro Lys Ala Asn Gly Val Lys Pro Ser Thr Val His Ile Ala Cys
                  95                 100                 105

 Thr Pro Gln Ala Ala Lys
                 110

<210> 4887
<211> 3967
<212> DNA
<213> Homo sapien

<400> 4887
 ccacgcgtcc gatttttgga aatcaagtgc aatattggaa gccatttcta 50

 ctaattttat ttcactttta aatttatgat ttgatttgaa tactatcatg 100

 ggaggagctg tgagtgctgg ggaagataat gatgacttaa ttgataattt 150

 aaaagaagct cagtatattc gtactgaaag agtggagcaa gccttcagag 200

 cgattgatcg tggagattac tatttggaag gctacagaga caatgcttac 250

 aaagacttag cctggaagca tggaaacatc cacttgtcag caccttgcat 300

 ttattctgaa gttatggaag cattgaaact tcaaccagga ttgtcttttc 350

 ttaacctggg aagtggaacc ggatatttaa gtacaatggt gggcttaatt 400

 ttaggtcctt ttggaataaa tcatgggatt gagcttcatt cagatgtggt 450

 ggaatatgcc aaggaaaaac tggagagctt catcaaaaat agtgatagct 500

 ttgataaatt tgagttctgt gaacctgcat ttgttgttgg taattgcctc 550

 cagatagctt ctgacagtca tcagtatgat cgaatttatt gtggagctgg 600

 agtacagaaa gaccatgaaa actacatgaa aatattacta aaagttggag 650

 gcatattagt catgcctata gaggatcagt taacacagat tatgcgaact 700

 ggacagaaca cttgggaaag taaaaatatc cttgctgttt catttgctcc 750

 acttgtgcaa ccaagtaaga atgataatgg caaaccagat tctgtgggac 800

 tccctccctg tgctgtcagg aatctacagg acttggctcg tatttacatt 850

 cgacgcacac ttagaaattt cataaatgat gagatgcagg ccaaggggat 900

 tcctcaaagg gctccaccca aaaggaaaag aaagagagtt aaacagagaa 950

 ttaacactta cgtatttgtg ggtaatcagc ttattcctca gcctctagac 1000

 agtgaagagg atgaaaaaat ggaagaggat atcaaagaag aggaggaaaa 1050

 agatcacaat gaagcaatga agccagagga gccacctcaa aatttactga 1100

 gagaaaaaat catgaagctg cccctccctg aatctttaaa agcttacttg 1150

 acatatttta gagacaaata acttagatca agaagaaaaa tgcctactga 1200

 taattccttt agtcttgaaa atgtagcatt tgttaggagt taaaagagag 1250

 aattatttct ttcatcagag caaattatag tggaaaaaaa aatcacttgt 1300

 ttctgtcagt aacacaaatg atgtattcag tgaataaaag aatccctttt 1350

 ataaaatcta tttttcttta aatcttggaa aaatgttgtt ttagctcaga 1400

 gtgatttcaa agtggaatgc aacagtagtc aagacttgtg tactataaat 1450

 ccttttctga ttccttacag atttgtagtg atgaggttta gatttaattt 1500

 tatatatggt ttaaataatt gttaagctta tataacctga tctgaattgc 1550

 agttgtttgc atttcctcta tgaaaacttc atttatctaa taaggaagtc 1600

 aaatgctttg tagactattt accttacttt tgttgcaatc actgttgttg 1650

 ggttgctgta tatatattcc gggcaatata tgagtgcaat aacaatacaa 1700

 gatattgaat aatttagctt taaaaaatcc cacaaatttt atgaaatttt 1750

 acagccctgc tacttttgct tttgaatctc ttgccaaaag acatgggtaa 1800

 aatatctgcc tctctcatag agattttaag agcacagcaa gtgaattatt 1850

 aaaacaaagt ctatacttaa tacaactctt tatatggacc ctttacattt 1900

 tcagtattta aaaaaataac tctatagaat tttaaaagta tatttagaat 1950

 tgttttttct gtagttcact gtataaagta tttggttttt taaaaaaagc 2000

 aaaaccattg ttatgtgtga ctcttgatag gacacagaac gagtgaatga 2050

 gcatgagtga ggccactttc ttggatggct gtaagtagca gggccagggt 2100

 agacctggtc agcggatgca ctttagcaga tggaacttct agtttatctg 2150

 aatatttatc tttgacaagg tagggctgag cctacatttg cttttgatct 2200

 atctagtata agaaatattc acagaaattg tatgtagata ccctttgttt 2250

 tgaaaatgct gttcagaatc atagtgtaat ctttgggacc tatgccatgt 2300

 tcatttcact ccttcccata ttttttgtgt ttcttttggt aaaactataa 2350

 tggttttcat tttttactta atatcacaca gttaaactgt ccatatttga 2400

 gctttatttt agcttatcag tgataaaaaa caggtagtaa ctgccattgt 2450

 ttgtttgttt tcctaataag gcctgaaaac agccattcct tgttaagaaa 2500

 gtgtacaatg taacatattt gctagagtta catggattat atatttctta 2550

 aagggaaaaa tttgagagta tcatggacta ccaccagcat tattattaca 2600

 gtagttactc agatttggtt aaggaagccc aagcaatgta tagtgaaagg 2650

 attattatct ctctgctaag attcagatat tgtttcagaa atctcagctc 2700

 cagtaattcc acaacatcta aaaacaaatg tttgtgatca tgtgtaagca 2750

 tgaaattgtt ccaagtaagt gaggatattt tagttatgtg aaagacagtt 2800

 tcatggaagg tatttgtttt gtaccagtgg ctgggatggt ggaattgggg 2850

 ttatttctac aattattctt agacgattac taaactgtta agaaatgccc 2900

 catatcattt ttgtatctag gaaagaaaaa aatcagtttc atactgttgt 2950

 catctgtcag aaatgctcat tttattttga attaaatgtg gcttttgaag 3000

 tacctagtta ccttgaattc ctggtgacca catgttttta tctggaaaac 3050

 ctggagaaag ttatctgtcc catctcccct gcttgttttt tttttttttt 3100

 tttttggttg gagctgctgt ttagatgatg cttttactat gcaggagaga 3150

 gtttttgtta aggatatatt tgaagattgg cttttccata ttgtccttca 3200

 ttctttgacc gtggcaaagt gtacagtaga ttttcatgat cattgcatat 3250

 ttcttgtcat tgaaatgtat cttttatgtt tttaaatgca ttcattttac 3300

 acttgtgagt ttatcattga ctttaagagg tagaaatgaa aaatgaaaat 3350

 taaagctaaa gcctttttat ctattaatgc agatatatta gaataagaat 3400

 attttgggtt tgtgtttatt ttttaatgaa tttatgttta cttgatatgg 3450

 aaaattacgc tttataggtg gaaaagtagc aaataaagat taagtaaaag 3500

 taagtgaaaa tgatggggaa tatagtattg gaattttata gctagttaaa 3550

 acaataagta tcatctaatt tgggtgttta ttttgcagat gagaaaacag 3600

 acctagaacc gtggcatgtt ttgcctgaaa catacagtga gttagagaca 3650

 gggcctaaga tagcttctag catcagatca atcccaagaa tccatcagca 3700

 acctcagacc aacccaagaa gataatttaa atctatactg cttattggtc 3750

 aatatatttg gttctagtat taataaagaa aaatgttatt aaaatagcat 3800

 acatagtagt aaaataaaat acaaaaagtg tgttgattta tagctgtttg 3850

 agatgataaa agtgaagcaa agcctgttaa atcattggaa gacttggaaa 3900

 attattttaa ataaacaatt acatgtaaaa aaaaaaaaaa aaaaaaaaaa 3950

 aaaaaaaaaa aaaaaaa 3967

<210> 4888
<211> 357
<212> PRT
<213> Homo sapien

<400> 4888
 Met Gly Gly Ala Val Ser Ala Gly Glu Asp Asn Asp Asp Leu Ile
   1               5                  10                  15

 Asp Asn Leu Lys Glu Ala Gln Tyr Ile Arg Thr Glu Arg Val Glu
                  20                  25                  30

 Gln Ala Phe Arg Ala Ile Asp Arg Gly Asp Tyr Tyr Leu Glu Gly
                  35                  40                  45

 Tyr Arg Asp Asn Ala Tyr Lys Asp Leu Ala Trp Lys His Gly Asn
                  50                  55                  60

 Ile His Leu Ser Ala Pro Cys Ile Tyr Ser Glu Val Met Glu Ala
                  65                  70                  75

 Leu Lys Leu Gln Pro Gly Leu Ser Phe Leu Asn Leu Gly Ser Gly
                  80                  85                  90

 Thr Gly Tyr Leu Ser Thr Met Val Gly Leu Ile Leu Gly Pro Phe
                  95                 100                 105

 Gly Ile Asn His Gly Ile Glu Leu His Ser Asp Val Val Glu Tyr
                 110                 115                 120

 Ala Lys Glu Lys Leu Glu Ser Phe Ile Lys Asn Ser Asp Ser Phe
                 125                 130                 135

 Asp Lys Phe Glu Phe Cys Glu Pro Ala Phe Val Val Gly Asn Cys
                 140                 145                 150

 Leu Gln Ile Ala Ser Asp Ser His Gln Tyr Asp Arg Ile Tyr Cys
                 155                 160                 165

 Gly Ala Gly Val Gln Lys Asp His Glu Asn Tyr Met Lys Ile Leu
                 170                 175                 180

 Leu Lys Val Gly Gly Ile Leu Val Met Pro Ile Glu Asp Gln Leu
                 185                 190                 195

 Thr Gln Ile Met Arg Thr Gly Gln Asn Thr Trp Glu Ser Lys Asn
                 200                 205                 210

 Ile Leu Ala Val Ser Phe Ala Pro Leu Val Gln Pro Ser Lys Asn
                 215                 220                 225

 Asp Asn Gly Lys Pro Asp Ser Val Gly Leu Pro Pro Cys Ala Val
                 230                 235                 240

 Arg Asn Leu Gln Asp Leu Ala Arg Ile Tyr Ile Arg Arg Thr Leu
                 245                 250                 255

 Arg Asn Phe Ile Asn Asp Glu Met Gln Ala Lys Gly Ile Pro Gln
                 260                 265                 270

 Arg Ala Pro Pro Lys Arg Lys Arg Lys Arg Val Lys Gln Arg Ile
                 275                 280                 285

 Asn Thr Tyr Val Phe Val Gly Asn Gln Leu Ile Pro Gln Pro Leu
                 290                 295                 300

 Asp Ser Glu Glu Asp Glu Lys Met Glu Glu Asp Ile Lys Glu Glu
                 305                 310                 315

 Glu Glu Lys Asp His Asn Glu Ala Met Lys Pro Glu Glu Pro Pro
                 320                 325                 330

 Gln Asn Leu Leu Arg Glu Lys Ile Met Lys Leu Pro Leu Pro Glu
                 335                 340                 345

 Ser Leu Lys Ala Tyr Leu Thr Tyr Phe Arg Asp Lys
                 350                 355

<210> 4889
<211> 1581
<212> DNA
<213> Homo sapien

<400> 4889
 gttggtagaa caccttttca ccttatgtca aaagcatgaa atatgaaggc 50

 ctagaaacaa aggttaattt atatacatag tactaataat tataccaagt 100

 ctactattat ttcctactag tcagatgatt tttatgaatg taaaatatta 150

 gaaaggcaca gtaagtgaca ccaagattaa taagacaaat aggtatggca 200

 gaaacagaga ggtatatgag ctgcataggg atctctgttg ataagaatct 250

 gtgtagactt ttttctcctt ccttcctttg atctttgatc atgggaagac 300

 atggaaaaag aaagctaact acagtgattt tgtccactac actgttattt 350

 ggttaaaaat tttagtttcc taatgagtat tagcatgtat gagaaattat 400

 gggagaaaaa ggcgcatcct agaaaaggtg tgcttaatta ctattgggga 450

 ttggttaaca tagcatggga gctggattgt cagagattca ttatctagaa 500

 aatggcaaca agagtttata aaacgaactt ctgtgagatt actttttagc 550

 tagcaaagac aaagatgtcc ttcagtaggt gaagtgataa actatgatac 600

 atccagatga tggaatacta ttgaggacta aaaagaaata agctgtcaag 650

 ccatgaaaac acatggaggg acgttaaatg catattacta agtgaaaaaa 700

 gctaatctga aagggctaca tactgtgtga ttctaactat ataacattcc 750

 ataaaaggca aaactgtgaa gacagcaaaa aaaaatcagc ggttgccagg 800

 gtttagaagg aagggaggga taaatgtgca gagcacagag gatttttagg 850

 ccagtgaaaa tacttcgtat gatactacaa tggtggaaac atgtcattat 900

 acatttatcc aaacccaaag aatgtccacc accaagagtg aaccctcaac 950

 tatggacttt gggtgatgat gtgtgggaca ggaggtatat gaaaaatctc 1000

 tgtaccttcc tcccaatttt gctgtgaact taaaactgct ctaaaaaaag 1050

 tcttttttaa aaaaagctct atgaactagt tggtattata aaccttaggc 1100

 catttcaagt aaaaattaca tatcaatgtt tattaaatac tgagttaata 1150

 gctgaatacc tctttcatat acaaataagt acatttgcaa ttttttaaaa 1200

 aagtcttaat tccattagta actgtggttt catagttgcc aaataactgt 1250

 aagctatgga tgttgcacaa gactgtgatt ttatttaatc atttcatatc 1300

 tatttaaaca tttccaaagc gcacattcat cttaatgttt tcacactatt 1350

 tttgctcaac aaaaagttat tttatgttaa tggatataag aagtattaat 1400

 aatatttcag tcaaggcaag agaacccgat aaagatcatt gctagagacg 1450

 tttaatgtta cctgtagcgg tacacttgtt aaagaagtga ttaagcagtt 1500

 acataaaatt ctgatcatag ctttgattga taccatgaag gtataattca 1550

 gtgcctggat actaacaact ttacttgttt a 1581

<210> 4890
<211> 52
<212> PRT
<213> Homo sapien

<400> 4890
 Met Ile Leu Gln Trp Trp Lys His Val Ile Ile His Leu Ser Lys
   1               5                  10                  15

 Pro Lys Glu Cys Pro Pro Pro Arg Val Asn Pro Gln Leu Trp Thr
                  20                  25                  30

 Leu Gly Asp Asp Val Trp Asp Arg Arg Tyr Met Lys Asn Leu Cys
                  35                  40                  45

 Thr Phe Leu Pro Ile Leu Leu
                  50

<210> 4891
<211> 2716
<212> DNA
<213> Homo sapien

<400> 4891
 gaccagaact tcctcggggg aggctgcagg ggagcaggcg catcctgcac 50

 agaacgctct agagcgcgca ggccaaagca ccaggctgct cctgacacgt 100

 gctgcaagag ggtccccgac ccgggggtcc agaccctgca cgcatgatgg 150

 ggaaggtgga ggcttccccc tcagctccgc ggagagaagc tgacactgcc 200

 aggctggaac cttccattcc ggcccagcct cttcctccct cgctgtgccg 250

 aggagggatc tagaagggac tttccagaga gggttagcgt gcagggtgtg 300

 gaaatggaat aaaagcatat gcaaataggc cttagctgcc ttcctctacc 350

 ccagcaaata agagtctctc cagaaagatg ctctttctcc aagacgcttg 400

 accgctcttc ctttcctgga tggcaccagc agggccgatt ggagtggtaa 450

 accctgggcc ggaaggcatg ccaaagggtg gacaggatgg acaggagaca 500

 gtagcacaac gaggaggggg agaacagcgg ctgaattgga aatgataaaa 550

 taaaatgaaa ttttaggagc tcgctggctg ggacaggcct ggactgcaag 600

 gaggggtctt tgcaccatct ctgaaaagcc gatgtgtatc ctcagctttg 650

 agaactgaat tccatgggtt gtgtcagtgt cagacctgtg aaattcagtt 700

 cttcagctgg gatatctctg tcatcgtggg cttgaggacc tggagagagt 750

 agatcctgaa gaactttttc agtctgctga agagcttgga agactggaga 800

 cagaaggcag agtctcaggc tctgaaggta taaggagtgt gagttcctgt 850

 gagaaacact catttgattg tgaaaagact tgaattctat gctaagcagg 900

 gttccaagta gctaaatgaa tgatctcagc aagtctctct tgctgctgct 950

 gctactcgtt tacatttatt gattacttac gatgattcag gtactgttgt 1000

 aagtgcttta catgctgtta tacgagactc ttgggagaaa tcactttaat 1050

 gaagcttgag acacatggca ttgccatgca atgatttttc ccccctcttc 1100

 acgggatcag agggaactaa tagaatgtga caatgattct ttagcaggga 1150

 ctgctgaggc ttctggttcc tttttaagat ctgcagtgaa agaagatgag 1200

 aaacatggat atgcccttct tttggtcccc ctcttccttt atttgatctc 1250

 tacttccttc tataaatata ttagggctac attgtccctt tgtatttcaa 1300

 acaaggcaaa aagaggttgt aattacactt tactgcaatc ctcagtttct 1350

 ccagggaaca ggaatgcaaa ggctttgaag gcctctctat ttgctgacat 1400

 ggtcagctgg gtgccatggg ccaagtcctt ctgttgccct cctctgtcac 1450

 caagtaagct aggtcctttc tgaggctcag gtttgctgtg atgatgatca 1500

 cttttaggca gaaggttaga ggcctcatga gtgctatatg gactttatta 1550

 ggctttagat ttgatgggga ataagggatg tgatttgtct tttgggaact 1600

 catctttgat tcatcattgt ctcttggtat cttggaattt ccatgtcatt 1650

 acagtctaca gaatgaaaga gtaacctgtc ccagaggaga ggcaggtgaa 1700

 agactccaca gcatgctcat tctcattctg tcttctcagt gacaccgagg 1750

 tttactgagt gcccactatg tgccaagcac tgtgctcagg gctttctttg 1800

 tatgcatgat ctcagtgaat ctcaccaagc ctcatctgga aaacggggac 1850

 aaattaacaa caggatggca aattgaaaaa cacgtaacca tgttctacag 1900

 atggaaaggg gtgcttggtt attatgaagg ccccctcgca agcgtgtggg 1950

 acatgggtgt gttctctggg ttgtactgat cagatcaagg acctccccca 2000

 cccttctcac actctgccca cttccgccct ttgcttatca gacccttagc 2050

 cagtgactca ttccagaacc agaaccttgg tgaaatctca accgacacca 2100

 gagatcggtg tcttcagtcc tagactgatg gagaaaatcc agaatatata 2150

 ctagaagctc caaatgctct gggtttcagc tcctctgtgc tgtggacact 2200

 gactttggct cagaactccg atttagtaca aaaggctcat ttttatttca 2250

 ggggcactct tcctaaagca aacctaataa atgaaatatg gaattcacag 2300

 atacacacac acattaaaaa attaacctag tgtatctgtg aggagtaggc 2350

 agaaattcac tgtataaaag aatgcttcat ttcatagaga atttgtgtta 2400

 agattccatt agatagtaca tttctcaaag atttttgagg ttgtatttgc 2450

 tttaccaaaa cttggtttat gtaagtggaa aaagcatgtt gcaaaataac 2500

 ttggtgtcta tgattcagtt tatgtaaaat aataaatgta tgtaggaata 2550

 cgtgtgttga aagatgtaca tcaatttgct aacaatggtt atctctgacg 2600

 tggtgggatt tgagatgtgt ttttcttttt ggttgtattt ttctctattg 2650

 tttgacttaa cacagaacat gtttggttac aacaataaag ttattgaaga 2700

 caaaaaaaaa aaaaaa 2716

<210> 4892
<211> 2684
<212> DNA
<213> Homo sapien

<400> 4892
 cggaagcagg aagtgagttt gcgaacggag cagctgctgc agggcccatg 50

 gcggacaccc agtacatcct gcccaatgac atcggcgtgt ctagcctgga 100

 ctgccgtgag gccttccgcc tgctgtcacc cacagagcgc ctctatgcct 150

 accacctgtc ccgtgccgcc tggtacggag gcctggctgt gctgcttcag 200

 acctcccctg aggcccccta catctatgct ctgctcagcc gcctcttccg 250

 cgcccaggac cccgaccagc tgcgccaaca tgccctggct gaaggcctta 300

 ccgaggagga gtatcaggcg ttcctggtct atgccgcggg tgtttactcc 350

 aacatgggca actacaagtc ctttggtgac accaagtttg ttcccaactt 400

 gcccaaggaa aagctggaac gggtgatcct agggagtgag gctgctcagc 450

 agcacccaga agaagtcagg ggcctctggc agacctgcgg ggagcttatg 500

 ttctctctgg agccaaggct tcgacacctc ggactgggga aggagggaat 550

 caccacctat ttctctggga attgtaccat ggaagatgcc aaattggccc 600

 aggactttct ggactcacag aacctcagtg cctacaacac ccggctcttc 650

 aaagaggtcg atggagaagg gaagccctac tacgaggtgc ggctggcttc 700

 tgtgcttggc tcagagcctt ccctggactc tgaggtgact tccaagctga 750

 agagctatga attccgggga agccctttcc aggtgacccg gggggactac 800

 gcgcccatcc tccagaaggt ggtggagcag ctggagaaag ccaaggccta 850

 tgcagccaac agccaccagg ggcagatgct ggcccagtat atagagagct 900

 tcacccaggg ctccatcgag gcccacaaga ggggctcccg cttctggatc 950

 caggacaaag gccccatcgt ggagagttac atcgggttca tcgagagcta 1000

 ccgcgacccc tttggttccc gaggagaatt tgaaggtttc gtagctgtgg 1050

 tgaacaaggc catgagtgcc aagtttgagc ggctggtggc gagcgcagag 1100

 cagctgctga aggagctgcc ctggccccca acctttgaga aggacaagtt 1150

 cctcacccct gacttcacct ccctggatgt tctcaccttc gctggctccg 1200

 gcatccctgc cggcatcaac atccccaact acgatgatct gaggcagacg 1250

 gaaggcttta agaacgtgtc gctggggaat gtgctggctg tggcctacgc 1300

 cacgcagcgg gagaagctta cctttctgga ggaggatgac aaggacctgt 1350

 acatcctctg gaaggggccc tccttcgatg tgcaggtggg cctgcacgag 1400

 ctgctgggcc atggcagtgg caagctcttc gtacaggacg aaaaaggagc 1450

 attcaacttt gaccaggaaa cagtgatcaa cccagagacg ggcgagcaga 1500

 ttcagagctg gtatcggagc ggggagacct gggatagcaa gttcagcacc 1550

 atcgcctcca gctacgaaga gtgccgggct gagagcgtgg gtctctacct 1600

 ctgtctccac ccgcaagtgc tggagatctt tggctttgag ggggctgatg 1650

 cggaggacgt gatctacgtg aactggctca acatggttcg ggccgggctg 1700

 ctcgctctgg agttctacac acctgaggcc ttcaactggc gacaggccca 1750

 tatgcaggcc cggtttgtga tcctgagagt cttgctggag gctggcgagg 1800

 gactcgttac catcactccc accacaggct ccgatgggcg cccagatgcc 1850

 cgggtccgcc tcgaccgcag caagatccgg tctgtgggca agcctgctct 1900

 agagcgcttc ctgcggagac ttcaggtgct gaagtccaca ggggatgtgg 1950

 ccggagggcg ggccctgtac gaggggtatg caacggtcac tgatgcgccc 2000

 cccgagtgct tcctcaccct cagggacacg gtgctgctgc gtaaggaatc 2050

 tcggaagctc attgttcagc ccaacactcg ccttgaaggc tcagacgtgc 2100

 agcttctgga atacgaggcg tcagctgctg gcctcatccg atccttctct 2150

 gagcgtttcc cagaggatgg acccgagttg gaggagatcc tcacacagct 2200

 ggccacagcc gatgcccgat tctggaaggg ccccagtgag gccccatctg 2250

 gccaagcttg aggaagatgt gtggccttgc ccccaattcc atcagaccaa 2300

 ggctgcaagt ggccctccat tcgtgtgtgt atttaggggc tggggagggg 2350

 gaggggcagg agcttggacc ttggtactac ctcagctgag ggtggtgaca 2400

 caaccccttc catttgtcag cactttccag cctgccaatt gcttcccctc 2450

 tgtgatctca tttcatctgc actgccatac gtggagtgag caagacaggg 2500

 cttaccatcc tgtctaccag atgaggaaat ggcagttctg agaagtcact 2550

 ggtctagatc ccgcaggtgg cacgtgacag ctagggttca aaacgttctc 2600

 accaaatcca atgctcctca catattaatt ttataaccag acaaataaat 2650

 attagagaca accaaaaaaa aaaaaaaaaa aaaa 2684

<210> 4893
<211> 737
<212> PRT
<213> Homo sapien

<400> 4893
 Met Ala Asp Thr Gln Tyr Ile Leu Pro Asn Asp Ile Gly Val Ser
   1               5                  10                  15

 Ser Leu Asp Cys Arg Glu Ala Phe Arg Leu Leu Ser Pro Thr Glu
                  20                  25                  30

 Arg Leu Tyr Ala Tyr His Leu Ser Arg Ala Ala Trp Tyr Gly Gly
                  35                  40                  45

 Leu Ala Val Leu Leu Gln Thr Ser Pro Glu Ala Pro Tyr Ile Tyr
                  50                  55                  60

 Ala Leu Leu Ser Arg Leu Phe Arg Ala Gln Asp Pro Asp Gln Leu
                  65                  70                  75

 Arg Gln His Ala Leu Ala Glu Gly Leu Thr Glu Glu Glu Tyr Gln
                  80                  85                  90

 Ala Phe Leu Val Tyr Ala Ala Gly Val Tyr Ser Asn Met Gly Asn
                  95                 100                 105

 Tyr Lys Ser Phe Gly Asp Thr Lys Phe Val Pro Asn Leu Pro Lys
                 110                 115                 120

 Glu Lys Leu Glu Arg Val Ile Leu Gly Ser Glu Ala Ala Gln Gln
                 125                 130                 135

 His Pro Glu Glu Val Arg Gly Leu Trp Gln Thr Cys Gly Glu Leu
                 140                 145                 150

 Met Phe Ser Leu Glu Pro Arg Leu Arg His Leu Gly Leu Gly Lys
                 155                 160                 165

 Glu Gly Ile Thr Thr Tyr Phe Ser Gly Asn Cys Thr Met Glu Asp
                 170                 175                 180

 Ala Lys Leu Ala Gln Asp Phe Leu Asp Ser Gln Asn Leu Ser Ala
                 185                 190                 195

 Tyr Asn Thr Arg Leu Phe Lys Glu Val Asp Gly Glu Gly Lys Pro
                 200                 205                 210

 Tyr Tyr Glu Val Arg Leu Ala Ser Val Leu Gly Ser Glu Pro Ser
                 215                 220                 225

 Leu Asp Ser Glu Val Thr Ser Lys Leu Lys Ser Tyr Glu Phe Arg
                 230                 235                 240

 Gly Ser Pro Phe Gln Val Thr Arg Gly Asp Tyr Ala Pro Ile Leu
                 245                 250                 255

 Gln Lys Val Val Glu Gln Leu Glu Lys Ala Lys Ala Tyr Ala Ala
                 260                 265                 270

 Asn Ser His Gln Gly Gln Met Leu Ala Gln Tyr Ile Glu Ser Phe
                 275                 280                 285

 Thr Gln Gly Ser Ile Glu Ala His Lys Arg Gly Ser Arg Phe Trp
                 290                 295                 300

 Ile Gln Asp Lys Gly Pro Ile Val Glu Ser Tyr Ile Gly Phe Ile
                 305                 310                 315

 Glu Ser Tyr Arg Asp Pro Phe Gly Ser Arg Gly Glu Phe Glu Gly
                 320                 325                 330

 Phe Val Ala Val Val Asn Lys Ala Met Ser Ala Lys Phe Glu Arg
                 335                 340                 345

 Leu Val Ala Ser Ala Glu Gln Leu Leu Lys Glu Leu Pro Trp Pro
                 350                 355                 360

 Pro Thr Phe Glu Lys Asp Lys Phe Leu Thr Pro Asp Phe Thr Ser
                 365                 370                 375

 Leu Asp Val Leu Thr Phe Ala Gly Ser Gly Ile Pro Ala Gly Ile
                 380                 385                 390

 Asn Ile Pro Asn Tyr Asp Asp Leu Arg Gln Thr Glu Gly Phe Lys
                 395                 400                 405

 Asn Val Ser Leu Gly Asn Val Leu Ala Val Ala Tyr Ala Thr Gln
                 410                 415                 420

 Arg Glu Lys Leu Thr Phe Leu Glu Glu Asp Asp Lys Asp Leu Tyr
                 425                 430                 435

 Ile Leu Trp Lys Gly Pro Ser Phe Asp Val Gln Val Gly Leu His
                 440                 445                 450

 Glu Leu Leu Gly His Gly Ser Gly Lys Leu Phe Val Gln Asp Glu
                 455                 460                 465

 Lys Gly Ala Phe Asn Phe Asp Gln Glu Thr Val Ile Asn Pro Glu
                 470                 475                 480

 Thr Gly Glu Gln Ile Gln Ser Trp Tyr Arg Ser Gly Glu Thr Trp
                 485                 490                 495

 Asp Ser Lys Phe Ser Thr Ile Ala Ser Ser Tyr Glu Glu Cys Arg
                 500                 505                 510

 Ala Glu Ser Val Gly Leu Tyr Leu Cys Leu His Pro Gln Val Leu
                 515                 520                 525

 Glu Ile Phe Gly Phe Glu Gly Ala Asp Ala Glu Asp Val Ile Tyr
                 530                 535                 540

 Val Asn Trp Leu Asn Met Val Arg Ala Gly Leu Leu Ala Leu Glu
                 545                 550                 555

 Phe Tyr Thr Pro Glu Ala Phe Asn Trp Arg Gln Ala His Met Gln
                 560                 565                 570

 Ala Arg Phe Val Ile Leu Arg Val Leu Leu Glu Ala Gly Glu Gly
                 575                 580                 585

 Leu Val Thr Ile Thr Pro Thr Thr Gly Ser Asp Gly Arg Pro Asp
                 590                 595                 600

 Ala Arg Val Arg Leu Asp Arg Ser Lys Ile Arg Ser Val Gly Lys
                 605                 610                 615

 Pro Ala Leu Glu Arg Phe Leu Arg Arg Leu Gln Val Leu Lys Ser
                 620                 625                 630

 Thr Gly Asp Val Ala Gly Gly Arg Ala Leu Tyr Glu Gly Tyr Ala
                 635                 640                 645

 Thr Val Thr Asp Ala Pro Pro Glu Cys Phe Leu Thr Leu Arg Asp
                 650                 655                 660

 Thr Val Leu Leu Arg Lys Glu Ser Arg Lys Leu Ile Val Gln Pro
                 665                 670                 675

 Asn Thr Arg Leu Glu Gly Ser Asp Val Gln Leu Leu Glu Tyr Glu
                 680                 685                 690

 Ala Ser Ala Ala Gly Leu Ile Arg Ser Phe Ser Glu Arg Phe Pro
                 695                 700                 705

 Glu Asp Gly Pro Glu Leu Glu Glu Ile Leu Thr Gln Leu Ala Thr
                 710                 715                 720

 Ala Asp Ala Arg Phe Trp Lys Gly Pro Ser Glu Ala Pro Ser Gly
                 725                 730                 735

 Gln Ala


<210> 4894
<211> 879
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 187-247, 338
<223> Unknown base

<400> 4894
 atttcccaga ctttgttttc tcattagcaa aacagaccta ataaaaggac 50

 tcatttcata ggttttttat gaggattaat tgagataaac cagataatac 100

 gcttaacacc gtggtacttg caatgaagaa aatggtgaat ggtacataca 150

 tggtaagtgg tcaatacatt ttagtcattc tattaannnn nnnnnnnnnn 200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnccc 250

 ttctgggtag ttgggagaag tcaagcatta ataccagtga agcacttcaa 300

 atggtgcttt gcatacagcg agtgctcaat taaatgtnaa aattcttaaa 350

 atcatcacca cgattctgac cttatggact ttgaagggca gatgttgtgt 400

 ctcattgctt tcgtgtccac aagacctggc acatagacga tgctcaataa 450

 atattatttg aaggagtgaa tgatggtgac atggttctta ggagttaaaa 500

 tgagaaaacc caaggagccg aaagcatgtc tctacgggga aaggttagag 550

 agcactgact caaaccatcg tctccaatta tgcagtttta atgaggaagc 600

 aagcccaacc ttgaacatta tttaagccag agttatccca ataagcattt 650

 tcctaccatg agtggtagat taagtagcat tgagtcatgt agtgaaagta 700

 atgtcccttc ttcataccat ttcaatgcct ctggtaagtc aagagaaagt 750

 ctttgataat agcctatttt taacacctct cacccttgtt tgtcagaaag 800

 agcagacctc agattcagag actttagcaa gcaaagatat ccagtaaaga 850

 aatgaaataa tggccgggca cagtggcta 879

<210> 4895
<211> 51
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 187-247, 338
<223> Unknown amino acid

<400> 4895
 Met Met Val Thr Trp Phe Leu Gly Val Lys Met Arg Lys Pro Lys
   1               5                  10                  15

 Glu Pro Lys Ala Cys Leu Tyr Gly Glu Arg Leu Glu Ser Thr Asp
                  20                  25                  30

 Ser Asn His Arg Leu Gln Leu Cys Ser Phe Asn Glu Glu Ala Ser
                  35                  40                  45

 Pro Thr Leu Asn Ile Ile
                  50

<210> 4896
<211> 2013
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 777, 811, 831-832, 857, 1634, 1721, 1769, 1990, 1992-1994
<223> Unknown base

<400> 4896
 ttttaagatg gagttttcgc tcttgttgcc caggctggag tgcagtggtg 50

 caatcttggc tcactgcaac ctctgccccc cgggttcagg cgattctctc 100

 ctctcagtct ctcaagtaac tgggattaca ggcacacacc accacggcca 150

 gctaattatt ttgtattttg agtcgagagg agaattcacc atattggcct 200

 caggtaatcc gcccgcctcg gcctcccaaa gtgttgggat tatgggcgtg 250

 agccagccac ggtgcccggc ccgttttatt gtttgaaaaa caagtacagg 300

 ttgttattat ccaagaattg ttgatagagt atatactgta tttgaagtgt 350

 agaactgagg cagaggctga ttaatataac tagtttacat ttgttagcct 400

 ttcacatctg tgaaggaata aagtacagac aaaagtggaa aacaaaccag 450

 aaaaaaaaaa attgtgaagc acagagctgc ttaaaagagt ggtgtcacat 500

 taaaagaaaa aagtcacaga aataagtcag tattttgttt agagactaga 550

 actccaactg ctagccaact gcctagaata tagtaaatat tttctagttt 600

 cttaaatgac tagtaatatt cctacattat gtgatggcat ttcccaaact 650

 gtttaattag atgttagatt tgtagccaaa tatgtctagg aaatgcttaa 700

 acaatataaa acagttttaa tgattggctt tttagaacgt tatatattag 750

 tgtgctttat gcatatccaa gaggtgngtg aggtatttgg ggtttttcag 800

 acttacttga ntacagatct ggagtatctc nnaacagttg ttttgtggaa 850

 aacactntgg caaactctga gtcttagtca ttaaaaatag tttttgggta 900

 aacaacagtg taatagaaat ggaaattact gattcacatt gagccatgaa 950

 gaatttattt tcagcgattt ttatagaagt tgctttatga caaagaaagc 1000

 tttggttaac tggcatttgg catttcacac ccctaaattt tctacatgag 1050

 gatttatttc tctggttctc tcactttctc actcagttat actgaattca 1100

 tttatgatga gcgctctcaa ccattcttat tcatcaaagc tgaagttggc 1150

 agagccctct ctggtacctg attagaagtc cgtcttccgt ctcataggga 1200

 agtgttagag atggataatg tttctgtgta gcagaagtag tcattatgtc 1250

 cccttaaatt cggtcacttt gactgcagta gagcttctta gtgagcagtc 1300

 tgtgatggag tatactttcg gagaagctca tggtggggga aacctggaat 1350

 ttatctaaat atttcatttc tttgataaat tacattaaaa aattaataag 1400

 agtatctatt tggtgaaatc attttcctcc acgtgaccaa atgagaaatt 1450

 tagtgaaaga tttaaaatca tttttcagac tttttccaca ttagttggga 1500

 agcaaacccc ttttttaagg caatgtcagt tattaagctt tagggaacca 1550

 catgccactt taggtaacac atgattggag agattgaaga gtgaagtccc 1600

 tgctttaaag tgtactcctg tggacacagt aatncatata tttaaaatgg 1650

 ttcatgttaa gagtaggtat atttctatct aaatactctg tagcttttgt 1700

 gattcaggga aatgagtgga ncctcacagg cacaagaatc tagtaaattc 1750

 taggtttctt gtgtggaant cagtgggcaa aatcttaact gagtgaattc 1800

 ttgattattg gtatcacatt tgttagtctg tatgtatctg tgtcatcgat 1850

 ctccttaaga agagactcgt agatattgac tgggagaccc aagctgaatg 1900

 ctaaaatctg ctccatggat ataagctgat gcagtcatca tttcacatta 1950

 aaatgtacca cagctatata tgcagcaaaa aaaaaaaaan annncgcccg 2000

 gccgcgaata taa 2013

<210> 4897
<211> 2503
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1499-1533
<223> Unknown base

<400> 4897
 gggggcgctc ggggaattaa aagaggggaa aaaaagcccg aagaaaactc 50

 acgccccaaa caaaacgcaa ggagaggagg gcgcgcggcc tgcagccctc 100

 gcccgcgtcc ccggccgcgg cgtgatgcgc gcggaccagc ccgcgacgcc 150

 cgggctgccg ctgtccccgc acctggacgc tggcgcggtg gccgcgcccc 200

 agcctcgatc gctcgccgcg gcgactcggc cccaggcttc cggcgccggt 250

 gggggccctc gctctccatg gggctgaggg actggctgag aaccgtgtgc 300

 tgctgctgcc ggtgcgagtg cttggaggag cgcgccctgc ctgagaagga 350

 gcccctcgtc agtgataaca atccatattc ctcatttgga gcaactctgg 400

 tgagggatga tgagaagaat ttatggagta tgccccatga tgtgtcccac 450

 acagaggcag acgacgacag aaccctgtac aatttgatag tcattcgtaa 500

 tcagcaggcc aaagactcag aggagtggca gaagctcaac tatgatatcc 550

 ataccctgcg gcaggttcga agggaagtaa gaaacagatg gaagtgcatc 600

 ttagaagatt taggttttca aaaggaagct gactctttgt tgtcagtgac 650

 taaactcagc accatcagtg attctaaaaa cacaaggaaa gctcgagaga 700

 tgttgttaaa actggctgaa gaaaccaata ttttcccaac aagttgggag 750

 ctctcagaga gatatctctt tgttgtggac cgtctcattg cacttgatgc 800

 tgcagaagag ttctttaagc ttgctcgtcg aacttacccc aagaagcctg 850

 gggttccatg cctggcagat ggccagaaag aactgcacta ccttccgttt 900

 ccaagtccct aaaggagagg ctcaggggca gaatgggaat tcttccatga 950

 ggactcagca gtcaaccaaa gttggacaat tacatgtaga agagagtgag 1000

 caaatagagt ttgcttagtg aaaaatgata ctgaattcta cataaatgta 1050

 aagtctttaa tctgaggacc ctgccccatg aattgtgcag gctgcattga 1100

 aacgccttgg tgatctcata tttaggaaga aagttaaaga gttggtcaga 1150

 tggatagttc ataatgggtg gttccattct gagagcccat tgccccagct 1200

 ttggttttag ttgtgtcata atctctgatc attaatccta ctgactgagt 1250

 ggactatttc agttaataaa acaatatgat taatagagag agctgtcatt 1300

 gagtcccaaa atggattgcc agttttaaaa taattattat aaaatgtatg 1350

 ctaaccccaa aataatacta ggcatgaggt gacctctctg atttggtcac 1400

 cttgtagaac cttggagggt gtcagggcat ctctttgagt atcagttatg 1450

 attattcaga agtatagatg tatcaaatga tagaaatgac aaggcatgnn 1500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnaagccct tggcatttta 1550

 tctggaatag catctgtaaa ctgaagtgtt tgacctctgt tttcttctct 1600

 cctctttcat ctgtttctga ttcgttggct ggcagctgca cctgtggggg 1650

 gacctctcat gcagacttgc acatatgcag ggagtattgc actgaagatc 1700

 tttgctggac cttcttctct tcagaagata attttcaaaa gggagcaatg 1750

 ctgtgaatgc agcttgcttc tctctacaga ttgagaagtc cagcttcaaa 1800

 agttacttgc cacttaagca aggaacttgt caagagatca tggttcatgt 1850

 tactgaaaag actttaagga tttgtaaggt taatccatag attgctgaga 1900

 acaatggaaa tatttttatt tttacagatt ttgcacttct gaattcaggt 1950

 taaaaactaa cttgtattta gtctgcttag aggactgtga cttgaaaatt 2000

 tttatatacc aatgagcttt ttggtagcgt ccacaatgtt taaaatattt 2050

 cataggcgag atccgtgttc tccatttatt aatgcattgt agaccaattt 2100

 aactgctgtg tttcaggaaa attcttccta gtttaataag caagctaaaa 2150

 gttttatttt ttatatttag tgcttaatct ttgcctcatg ttatgtaaaa 2200

 ttagcctgca gatattttct ctcaattctg tagactctcg caagataaac 2250

 attcaaacag tgaaacaaac aataaaataa ataaacctaa ggatgtcgta 2300

 ttgttttact ctctgtctca gaatttgtat tttgcctttc tgcctttttt 2350

 atgtcaaaat agatgagatt gtgtgcatct ataaattgtt accacagtat 2400

 ttttgataat gaataaggat aggactatct ctgtgattat taaaatacat 2450

 ggaattatcc aggaaatttt ccttacaagg aattaaaaga ctcctgtatt 2500

 tac 2503

<210> 4898
<211> 303
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1499-1533
<223> Unknown amino acid

<400> 4898
 Gly Gly Ala Arg Gly Ile Lys Arg Gly Glu Lys Lys Pro Glu Glu
   1               5                  10                  15

 Asn Ser Arg Pro Lys Gln Asn Ala Arg Arg Gly Gly Arg Ala Ala
                  20                  25                  30

 Cys Ser Pro Arg Pro Arg Pro Arg Pro Arg Arg Asp Ala Arg Gly
                  35                  40                  45

 Pro Ala Arg Asp Ala Arg Ala Ala Ala Val Pro Ala Pro Gly Arg
                  50                  55                  60

 Trp Arg Gly Gly Arg Ala Pro Ala Ser Ile Ala Arg Arg Gly Asp
                  65                  70                  75

 Ser Ala Pro Gly Phe Arg Arg Arg Trp Gly Pro Ser Leu Ser Met
                  80                  85                  90

 Gly Leu Arg Asp Trp Leu Arg Thr Val Cys Cys Cys Cys Arg Cys
                  95                 100                 105

 Glu Cys Leu Glu Glu Arg Ala Leu Pro Glu Lys Glu Pro Leu Val
                 110                 115                 120

 Ser Asp Asn Asn Pro Tyr Ser Ser Phe Gly Ala Thr Leu Val Arg
                 125                 130                 135

 Asp Asp Glu Lys Asn Leu Trp Ser Met Pro His Asp Val Ser His
                 140                 145                 150

 Thr Glu Ala Asp Asp Asp Arg Thr Leu Tyr Asn Leu Ile Val Ile
                 155                 160                 165

 Arg Asn Gln Gln Ala Lys Asp Ser Glu Glu Trp Gln Lys Leu Asn
                 170                 175                 180

 Tyr Asp Ile His Thr Leu Arg Gln Val Arg Arg Glu Val Arg Asn
                 185                 190                 195

 Arg Trp Lys Cys Ile Leu Glu Asp Leu Gly Phe Gln Lys Glu Ala
                 200                 205                 210

 Asp Ser Leu Leu Ser Val Thr Lys Leu Ser Thr Ile Ser Asp Ser
                 215                 220                 225

 Lys Asn Thr Arg Lys Ala Arg Glu Met Leu Leu Lys Leu Ala Glu
                 230                 235                 240

 Glu Thr Asn Ile Phe Pro Thr Ser Trp Glu Leu Ser Glu Arg Tyr
                 245                 250                 255

 Leu Phe Val Val Asp Arg Leu Ile Ala Leu Asp Ala Ala Glu Glu
                 260                 265                 270

 Phe Phe Lys Leu Ala Arg Arg Thr Tyr Pro Lys Lys Pro Gly Val
                 275                 280                 285

 Pro Cys Leu Ala Asp Gly Gln Lys Glu Leu His Tyr Leu Pro Phe
                 290                 295                 300

 Pro Ser Pro


<210> 4899
<211> 1809
<212> DNA
<213> Homo sapien

<400> 4899
 ctcaaagtaa atccagtgca tctgtatata tgtgtagata gcagcaacaa 50

 acaatcctga aacattattt ttggctgtta ggtaagtaaa cgtgatgata 100

 attataaaca acattcaaat aaccttggac cttggtgaaa tgacttgtgg 150

 tggccagaat ggtgcaacaa gatgttattt gcaagttttt ttaagacaca 200

 aatatctcag atactaataa tgagaataaa gactgttgaa tatgaaatta 250

 aagccaagca ataatgtgcc aaaaagaggc agttatacca gcaaatgcat 300

 ctattatggg cacaccatta tataatgatg gtttgcttta tgaagactga 350

 ctgtaaccca caggataaaa taagcaaagg catagtttct gctttcttcc 400

 tggaaaaact tgtttagaag cttcataaag aggtacagca ctaatgagca 450

 ttagtcagga tacagttggc atctatgttt ttatgtgagc ccagagggaa 500

 gaggagccac tcaaagtctt gctggcttaa aactcaagac agctgcaacc 550

 agaagttttg ttgaaatgga gactttaaac ttatggtaat tactctttct 600

 ggacactagc atgtagaaag caattcagtt aactctgccc agaggattac 650

 cagctttagc tgtgaaaaaa tgggctcccg gatgtaaaat cactaaaaca 700

 tgagatcttg tatccaaaga ggcttcaaat gatgccttac agaaaacgat 750

 gctccagatg ggcacttcta aatgctaact cttcatcaag tatctttctg 800

 gattcaagct caaaattaat tggctgcaaa atagtaggaa taaaaatcac 850

 atattttaca ctttagaaaa ggatattgat gatcaacctg catggtgata 900

 attatgatga gataccccag tgatttaatg atgttagaaa gaattaaatg 950

 ggagagaatt gctaacagct ttcttgatct cttaactatg gagatgtcat 1000

 tcatttattt ctggggtgaa aattatagct tgctttttga cattgctgct 1050

 agtattgttc tttgttgctt taaaaattgt ctctctttag aaaaactctt 1100

 gagcagttaa acagtttttt ttctgattca tatcattgct tttaataaca 1150

 tgtaaaggct gtgtgtagag caaactatat aaaatgagta gaaagggctt 1200

 actcatgtta attggcatcc ttgatgattt tagttgagat tccttaacat 1250

 ttattttaga tcacatcttt acgtaactta tttttcctaa tgttttccat 1300

 cgtgtcttaa aatgatgctg gtatatcagg agattgcagt attatagtca 1350

 tactccccaa tccctagagg agaggaaaga ctaattcttg ttttaagggc 1400

 ccctggagat accttttatt aaggttgaaa aaggtcaaca cagcctgaaa 1450

 ataagaaaaa tatatactag caattactaa ttttctaaat gtgtgtatct 1500

 ctgctgtact aatgtgtgaa caatatgtcg tgcataatac tgtagctggt 1550

 cgtggtatgt caatacattc tgtgagtgtg tacagtctga gtgatcagtt 1600

 ttctattttt atgtgtaaaa aaaataactt gtcgtatccc atttaaaggc 1650

 caatttctgt attcaggcag gcatatgtac atacatgaat aaagccaaca 1700

 aaagtgtgca catgtattca gtaacagaat ttgtcctttt atttttgaag 1750

 gtcagaaagg gctgtttgat ttgtgttttt gttttatcat ctccttgagt 1800

 aggtaacat 1809

<210> 4900
<211> 67
<212> PRT
<213> Homo sapien

<400> 4900
 Met Arg Tyr Pro Ser Asp Leu Met Met Leu Glu Arg Ile Lys Trp
   1               5                  10                  15

 Glu Arg Ile Ala Asn Ser Phe Leu Asp Leu Leu Thr Met Glu Met
                  20                  25                  30

 Ser Phe Ile Tyr Phe Trp Gly Glu Asn Tyr Ser Leu Leu Phe Asp
                  35                  40                  45

 Ile Ala Ala Ser Ile Val Leu Cys Cys Phe Lys Asn Cys Leu Ser
                  50                  55                  60

 Leu Glu Lys Leu Leu Ser Ser
                  65

<210> 4901
<211> 3180
<212> DNA
<213> Homo sapien

<400> 4901
 atacagtttc tctttgccag actagactaa agaaggagca ctactttatt 50

 ctgataaaac aggtctatgc agctaccagg acaatggaat ctacgttgac 100

 tttagcaacg gaacaacctg ttaagaagaa cactcttaag aaatataaaa 150

 tagcttgcat tgttcttctt gctttgctgg tgatcatgtc acttggatta 200

 ggcctggggc ttggactcag gaaactggaa aagcaaggca gctgcaggaa 250

 gaagtgcttt gatgcatcat ttagaggact ggagaactgc cggtgtgatg 300

 tggcatgtaa agaccgaggt gattgctgct gggattttga agacacctgt 350

 gtggaatcaa ctcgaatatg gatgtgcaat aaatttcgtt gtggagagac 400

 cagattagag gccagccttt gctcttgttc agatgactgt ttgcagagga 450

 aagattgctg tgctgactat aagagtgttt gccaaggaga aacctcatgg 500

 ctggaagaaa actgtgacac agcccagcag tctcagtgcc cagaagggtt 550

 tgacctgcca ccagttatct tgttttctat ggatggattt agagctgaat 600

 atttatacac atgggatact ttaatgccaa atatcaataa actgaaaaca 650

 tgtggaattc attcaaaata catgagagct atgtatccta ccaaaacctt 700

 cccaaatcat tacaccattg tcacgggctt gtatccggag tcacatggca 750

 tcattgacaa taatatgtat gatgtaaatc tcaacaagaa tttttcactt 800

 tcttcaaagg aacaaaataa tccagcctgg tggcatgggc aaccaatgtg 850

 gctgacagca atgtatcaag gtttaaaagc cgctacctac ttttggcccg 900

 gatcagaagt ggctataaat ggctcctttc cttccatata catgccttac 950

 aacggaagtg tcccatttga agagaggatt tctacactgt taaaatggct 1000

 ggacctgccc aaagctgaga gacccaggtt ttataccatg ttttttgaag 1050

 aacctgattc ctctggacat gcaggtggac cagtcagtgc cagagtaatt 1100

 aaagccttac aggtagtaga tcatgctttt gggatgttga tggaaggcct 1150

 gaagcagcgg aatttgcaca actgtgtcaa tatcatcctt ctggctgacc 1200

 atggaatgga ccagacttat tgtaacaaga tggaatacat gactgattat 1250

 tttcccagaa taaacttctt ctacatgtac gaagggcctg ccccccgcgt 1300

 ccgagctcat aatatacctc atgacttttt tagttttaat tctgaggaaa 1350

 ttgttagaaa cctcagttgc cgaaaacctg atcagcattt caagccctat 1400

 ttgactcctg atttgccaaa gcgactgcac tatgccaaga acgtcagaat 1450

 cgacaaagtt catctctttg tggatcaaca gtggctggct gttaggagta 1500

 aatcaaatac aaattgtgga ggaggcaacc atggttataa caatgagttt 1550

 aggagcatgg aggctatctt tctggcacat ggacccagtt ttaaagagaa 1600

 gactgaagtt gaaccatttg aaaatattga agtctataac ctaatgtgtg 1650

 atcttctacg cattcaacca gcaccaaaca atggaaccca tggtagttta 1700

 aaccatcttc tgaaggtgcc tttttatgag ccatcccatg cagaggaggt 1750

 gtcaaagttt tctgtttgtg gctttgctaa tccattgccc acagagtctc 1800

 ttgactgttt ctgccctcac ctacaaaata gtactcagct ggaacaagtg 1850

 aatcagatgc taaatctcac ccaagaagaa ataacagcaa cagtgaaagt 1900

 aaatttgcca tttgggaggc ctagggtact gcagaagaac gtggaccact 1950

 gtctccttta ccacagggaa tatgtcagtg gatttggaaa agctatgagg 2000

 atgcccatgt ggagttcata cacagtcccc cagttgggag acacatcgcc 2050

 tctgcctccc actgtcccag actgtctgcg ggctgatgtc agggttcctc 2100

 cttctgagag ccaaaaatgt tccttctatt tagcagacaa gaatatcacc 2150

 cacggcttcc tctatcctcc tgccagcaat agaacatcag atagccaata 2200

 tgatgcttta attactagca atttggtacc tatgtatgaa gaattcagaa 2250

 aaatgtggga ctacttccac agtgttcttc ttataaaaca tgccacagaa 2300

 agaaatggag taaatgtggt tagtggacca atatttgatt ataattatga 2350

 tggccatttt gatgctccag atgaaattac caaacattta gccaacactg 2400

 atgttcccat cccaacacac tactttgtgg tgctgaccag ttgtaaaaac 2450

 aagagccaca caccggaaaa ctgccctggg tggctggatg tcctaccctt 2500

 tatcatccct caccgaccta ccaacgtgga gagctgtcct gaaggtaaac 2550

 cagaagctct ttgggttgaa gaaagattta cagctcacat tgcccgggtc 2600

 cgtgatgtag aacttctcac tgggcttgac ttctatcagg ataaagtgca 2650

 gcctgtctct gaaattttgc aactaaagac atatttacca acatttgaaa 2700

 ccactattta acttaataat gtctacttaa tatataattt actgtataaa 2750

 gtaattttgg caaaatataa gtgatttttt tctggagaat tgtaaaataa 2800

 agttttctat ttttccttaa gtcccctaaa agccataatt tttattattc 2850

 ctttttctct tttttcaatt ctatgaatat gtattatttt aaagttatat 2900

 ttttcacaca gagatgatgc tatattacac cttccctttt ttgttggttt 2950

 cttaaactct aatctcatga cagattatac cttccttatt acttgtttta 3000

 tcttactcag aatctttgaa tatatttttc tgcccagaat tatctaaaca 3050

 aaagggagaa caaaagaagt atgtctcact tgggaactga atcaactcta 3100

 aatcagtttt gtcacaaaac tttttgtatt tgactggcaa tgctgattaa 3150

 aattaaaaat gcacaaaaaa aaaaaaaaaa 3180

<210> 4902
<211> 875
<212> PRT
<213> Homo sapien

<400> 4902
 Met Glu Ser Thr Leu Thr Leu Ala Thr Glu Gln Pro Val Lys Lys
   1               5                  10                  15

 Asn Thr Leu Lys Lys Tyr Lys Ile Ala Cys Ile Val Leu Leu Ala
                  20                  25                  30

 Leu Leu Val Ile Met Ser Leu Gly Leu Gly Leu Gly Leu Gly Leu
                  35                  40                  45

 Arg Lys Leu Glu Lys Gln Gly Ser Cys Arg Lys Lys Cys Phe Asp
                  50                  55                  60

 Ala Ser Phe Arg Gly Leu Glu Asn Cys Arg Cys Asp Val Ala Cys
                  65                  70                  75

 Lys Asp Arg Gly Asp Cys Cys Trp Asp Phe Glu Asp Thr Cys Val
                  80                  85                  90

 Glu Ser Thr Arg Ile Trp Met Cys Asn Lys Phe Arg Cys Gly Glu
                  95                 100                 105

 Thr Arg Leu Glu Ala Ser Leu Cys Ser Cys Ser Asp Asp Cys Leu
                 110                 115                 120

 Gln Arg Lys Asp Cys Cys Ala Asp Tyr Lys Ser Val Cys Gln Gly
                 125                 130                 135

 Glu Thr Ser Trp Leu Glu Glu Asn Cys Asp Thr Ala Gln Gln Ser
                 140                 145                 150

 Gln Cys Pro Glu Gly Phe Asp Leu Pro Pro Val Ile Leu Phe Ser
                 155                 160                 165

 Met Asp Gly Phe Arg Ala Glu Tyr Leu Tyr Thr Trp Asp Thr Leu
                 170                 175                 180

 Met Pro Asn Ile Asn Lys Leu Lys Thr Cys Gly Ile His Ser Lys
                 185                 190                 195

 Tyr Met Arg Ala Met Tyr Pro Thr Lys Thr Phe Pro Asn His Tyr
                 200                 205                 210

 Thr Ile Val Thr Gly Leu Tyr Pro Glu Ser His Gly Ile Ile Asp
                 215                 220                 225

 Asn Asn Met Tyr Asp Val Asn Leu Asn Lys Asn Phe Ser Leu Ser
                 230                 235                 240

 Ser Lys Glu Gln Asn Asn Pro Ala Trp Trp His Gly Gln Pro Met
                 245                 250                 255

 Trp Leu Thr Ala Met Tyr Gln Gly Leu Lys Ala Ala Thr Tyr Phe
                 260                 265                 270

 Trp Pro Gly Ser Glu Val Ala Ile Asn Gly Ser Phe Pro Ser Ile
                 275                 280                 285

 Tyr Met Pro Tyr Asn Gly Ser Val Pro Phe Glu Glu Arg Ile Ser
                 290                 295                 300

 Thr Leu Leu Lys Trp Leu Asp Leu Pro Lys Ala Glu Arg Pro Arg
                 305                 310                 315

 Phe Tyr Thr Met Phe Phe Glu Glu Pro Asp Ser Ser Gly His Ala
                 320                 325                 330

 Gly Gly Pro Val Ser Ala Arg Val Ile Lys Ala Leu Gln Val Val
                 335                 340                 345

 Asp His Ala Phe Gly Met Leu Met Glu Gly Leu Lys Gln Arg Asn
                 350                 355                 360

 Leu His Asn Cys Val Asn Ile Ile Leu Leu Ala Asp His Gly Met
                 365                 370                 375

 Asp Gln Thr Tyr Cys Asn Lys Met Glu Tyr Met Thr Asp Tyr Phe
                 380                 385                 390

 Pro Arg Ile Asn Phe Phe Tyr Met Tyr Glu Gly Pro Ala Pro Arg
                 395                 400                 405

 Val Arg Ala His Asn Ile Pro His Asp Phe Phe Ser Phe Asn Ser
                 410                 415                 420

 Glu Glu Ile Val Arg Asn Leu Ser Cys Arg Lys Pro Asp Gln His
                 425                 430                 435

 Phe Lys Pro Tyr Leu Thr Pro Asp Leu Pro Lys Arg Leu His Tyr
                 440                 445                 450

 Ala Lys Asn Val Arg Ile Asp Lys Val His Leu Phe Val Asp Gln
                 455                 460                 465

 Gln Trp Leu Ala Val Arg Ser Lys Ser Asn Thr Asn Cys Gly Gly
                 470                 475                 480

 Gly Asn His Gly Tyr Asn Asn Glu Phe Arg Ser Met Glu Ala Ile
                 485                 490                 495

 Phe Leu Ala His Gly Pro Ser Phe Lys Glu Lys Thr Glu Val Glu
                 500                 505                 510

 Pro Phe Glu Asn Ile Glu Val Tyr Asn Leu Met Cys Asp Leu Leu
                 515                 520                 525

 Arg Ile Gln Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn
                 530                 535                 540

 His Leu Leu Lys Val Pro Phe Tyr Glu Pro Ser His Ala Glu Glu
                 545                 550                 555

 Val Ser Lys Phe Ser Val Cys Gly Phe Ala Asn Pro Leu Pro Thr
                 560                 565                 570

 Glu Ser Leu Asp Cys Phe Cys Pro His Leu Gln Asn Ser Thr Gln
                 575                 580                 585

 Leu Glu Gln Val Asn Gln Met Leu Asn Leu Thr Gln Glu Glu Ile
                 590                 595                 600

 Thr Ala Thr Val Lys Val Asn Leu Pro Phe Gly Arg Pro Arg Val
                 605                 610                 615

 Leu Gln Lys Asn Val Asp His Cys Leu Leu Tyr His Arg Glu Tyr
                 620                 625                 630

 Val Ser Gly Phe Gly Lys Ala Met Arg Met Pro Met Trp Ser Ser
                 635                 640                 645

 Tyr Thr Val Pro Gln Leu Gly Asp Thr Ser Pro Leu Pro Pro Thr
                 650                 655                 660

 Val Pro Asp Cys Leu Arg Ala Asp Val Arg Val Pro Pro Ser Glu
                 665                 670                 675

 Ser Gln Lys Cys Ser Phe Tyr Leu Ala Asp Lys Asn Ile Thr His
                 680                 685                 690

 Gly Phe Leu Tyr Pro Pro Ala Ser Asn Arg Thr Ser Asp Ser Gln
                 695                 700                 705

 Tyr Asp Ala Leu Ile Thr Ser Asn Leu Val Pro Met Tyr Glu Glu
                 710                 715                 720

 Phe Arg Lys Met Trp Asp Tyr Phe His Ser Val Leu Leu Ile Lys
                 725                 730                 735

 His Ala Thr Glu Arg Asn Gly Val Asn Val Val Ser Gly Pro Ile
                 740                 745                 750

 Phe Asp Tyr Asn Tyr Asp Gly His Phe Asp Ala Pro Asp Glu Ile
                 755                 760                 765

 Thr Lys His Leu Ala Asn Thr Asp Val Pro Ile Pro Thr His Tyr
                 770                 775                 780

 Phe Val Val Leu Thr Ser Cys Lys Asn Lys Ser His Thr Pro Glu
                 785                 790                 795

 Asn Cys Pro Gly Trp Leu Asp Val Leu Pro Phe Ile Ile Pro His
                 800                 805                 810

 Arg Pro Thr Asn Val Glu Ser Cys Pro Glu Gly Lys Pro Glu Ala
                 815                 820                 825

 Leu Trp Val Glu Glu Arg Phe Thr Ala His Ile Ala Arg Val Arg
                 830                 835                 840

 Asp Val Glu Leu Leu Thr Gly Leu Asp Phe Tyr Gln Asp Lys Val
                 845                 850                 855

 Gln Pro Val Ser Glu Ile Leu Gln Leu Lys Thr Tyr Leu Pro Thr
                 860                 865                 870

 Phe Glu Thr Thr Ile
                 875

<210> 4903
<211> 603
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 551-552, 554, 559, 566
<223> Unknown base

<400> 4903
 tcacacacag agaaggcagc agaactggtt ccagagcctt tatgctagaa 50

 tagaaagtgc ctgttatttt gttcattctc ctcctcgtcc agtgtacagc 100

 tgtagtgatg gggaaacagg aaatcaatta ctaggttgcc actaagtcta 150

 caaactattg aagaccagaa tttacataaa tcgtatgcag tcccacatct 200

 gacaggcttg caaaaccttc cacatttcca tgagtaagcc tatccaaata 250

 gtactacttc tcaattgcaa atcataacaa cctcttgtgt ggccgtcaga 300

 gctgactaag cagaaactat gatcctctga atttagtatt tttcctgttt 350

 gccaaaaatg atgtgtcatt agtgacgaag ttattcttaa agttccttta 400

 acaaaactgt gatttatatc aaataacaat ggcttggagg gggtatggaa 450

 aattgattat tcttcctaac aaatctatta attttattaa acttggtctc 500

 cctccctttt tcttggatgt ttataaaatt taagtctttc taaaaaaaat 550

 nnanaaatna aaaatntgta tcccactgcc ttctggcctc catggattct 600

 gat 603

<210> 4904
<211> 47
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 551-552, 554, 559, 566
<223> Unknown amino acid

<400> 4904
 His Thr Gln Arg Arg Gln Gln Asn Trp Phe Gln Ser Leu Tyr Ala
   1               5                  10                  15

 Arg Ile Glu Ser Ala Cys Tyr Phe Val His Ser Pro Pro Arg Pro
                  20                  25                  30

 Val Tyr Ser Cys Ser Asp Gly Glu Thr Gly Asn Gln Leu Leu Gly
                  35                  40                  45

 Cys His


<210> 4905
<211> 2731
<212> DNA
<213> Homo sapien

<400> 4905
 tttaaccatt ctaactttgc cttgggatat tgaaaattct gaatcagtga 50

 ggtatctaaa taatttatat tttcaaaaaa taatgtttat tttataattc 100

 tgagtgtaaa acactatcag aaaagtaatc ctcatgctca ctaaacaaac 150

 ctactctaag acactcaaca accagaacag ttttattatt gagttgtgta 200

 caaaaatctt gactgtccag atgaaatagt ttttcagcct gcagtgtgtt 250

 agtgatatat ctcaaggaga tgaaccaata aagtacagac tttgtggtct 300

 gaagctctgt tgtgaaaaaa taagctaaac caattcacac tgacagtata 350

 atttgattca agtgcagctc cagttcaata aaaactaatg tttttaaaat 400

 taactttgtt ttgtatttgg ttcaactcct tgctagttct ctctctatat 450

 aatttataaa aactgcatgt tgctaatctc atgatcctgt gcatgtggac 500

 tactctgcct ttaacttttt tacaaaaaca tgtttgttca tagattaaat 550

 aaaagtatgt tttcaactta atgtctaatg ttttctgaca attgtaagaa 600

 taattttgaa atggaaatgc tgctgtttag tttccacagt gcctacacaa 650

 cctgataatc cattttctca ccctgacaaa ctcaaaagga tgagcaagtc 700

 tgttccagca tttctccaag atgagagtga tgacagagaa acagatacag 750

 catcagaaag cagttaccag ctcagcagac acaagaagag cccgagctct 800

 ttaaccaatc ttagcagctc ctctggcatg acgtccttgt cttctgtgag 850

 tggcagtgtg atgagtgttt atagtggaga ctttggcaat ctggaagtta 900

 aaggaaatat tcagtttgca attgaatatg tggagtcact gaaggagttg 950

 catgtttttg tggcccagtg taaggactta gcagcagcgg atgtaaaaaa 1000

 acagcgttca gacccatatg taaaggccta tttgctacca gacaaaggca 1050

 aaatgggcaa gaagaaaaca ctcgtagtga agaaaacctt gaatcctgtg 1100

 tataacgaaa tactgcggta taaaattgaa aaacaaatct taaagacaca 1150

 gaaattgaac ctgtccattt ggcatcggga tacatttaag cgcaatagtt 1200

 tcctagggga ggtggaactt gatttggaaa catgggactg ggataacaaa 1250

 cagaataaac aattgagatg gtaccctctg aagcggaaga cagcaccagt 1300

 tgcccttgaa gcagaaaaca gaggtgaaat gaaactagct ctccagtatg 1350

 tcccagagcc agtccctggt aaaaagcttc ctacaactgg agaagtgcac 1400

 atctgggtga aggaatgcct tgatctacca ctgctaaggg gaagtcatct 1450

 aaattctttt gttaaatgta ccatccttcc agatacaagt aggaaaagtc 1500

 gccagaagac aagagctgta gggaaaacca ccaaccctat cttcaaccac 1550

 actatggtgt atgatgggtt caggcctgaa gatctgatgg aagcctgtgt 1600

 agagcttact gtctgggacc attacaaatt aaccaaccaa tttttgggag 1650

 gtcttcgtat tggctttgga acaggtaaaa gttatgggac tgaagtggac 1700

 tggatggact ctacttcaga ggaagttgct ctctgggaga agatggtaaa 1750

 ctcccccaat acttggattg aagcaacact gcctctcaga atgcttttga 1800

 ttgccaagat ttccaaatga gcccaaattc cactggctcc tccactgaaa 1850

 actactaaac cggtggaatc tgatcttgaa aatctgagta ggtggacaaa 1900

 tatcctcact ttctatctat tgcacctaag gaatactaca cagcatgtaa 1950

 aagtcaatct gcatgtgctt ctttgattac aaggcccaag ggatttaaat 2000

 ataacaaaat gtgtaatttg tgactctaat attaaataag atatttgaac 2050

 aagctaggaa aattgaattt ctgctgctgc ttcaaagaaa aagctgcccc 2100

 agagcattaa acatggggta ttgttaagaa gcaaaatgtt cttgtttgcc 2150

 atcatgtgtt tcacaccaca attctgtgcc acagttaaga gggtctggta 2200

 cccttgcagg acctttgtag gttgtgggaa aaagtcgcag aaagatactc 2250

 aaagtggagc agggaatgga gacagacatc agtgatgata aaaaaaaaaa 2300

 aggaccttaa gaaactattt actctgtaat ctctaataaa atatggaatt 2350

 ccatattagg gcaatgagac tgaaactact ggtgtttttc tgccttgaga 2400

 aaacaaacag ttaaaacaag cctcaaatgt attttagtgc cacccactgg 2450

 ccataggtac aattcagttg ttggcttgtt ttgacttaat tctaaaatag 2500

 gtctcaagcc tgtattttta tgagtttatt tttttaaaac cctgcatata 2550

 tatgattgtt tttcttataa ctttactata tgaaagcagc ataagagtag 2600

 tcacaaacat gttttgcaac aaagttttaa ttagaatgta agttgctcag 2650

 ttatactgtt cttcttatgt atgtaaaatt ttcgtatttt gtaaaaaccc 2700

 ttagaataaa ttatcatttg atttaaattg t 2731

<210> 4906
<211> 376
<212> PRT
<213> Homo sapien

<400> 4906
 Met Ser Lys Ser Val Pro Ala Phe Leu Gln Asp Glu Ser Asp Asp
   1               5                  10                  15

 Arg Glu Thr Asp Thr Ala Ser Glu Ser Ser Tyr Gln Leu Ser Arg
                  20                  25                  30

 His Lys Lys Ser Pro Ser Ser Leu Thr Asn Leu Ser Ser Ser Ser
                  35                  40                  45

 Gly Met Thr Ser Leu Ser Ser Val Ser Gly Ser Val Met Ser Val
                  50                  55                  60

 Tyr Ser Gly Asp Phe Gly Asn Leu Glu Val Lys Gly Asn Ile Gln
                  65                  70                  75

 Phe Ala Ile Glu Tyr Val Glu Ser Leu Lys Glu Leu His Val Phe
                  80                  85                  90

 Val Ala Gln Cys Lys Asp Leu Ala Ala Ala Asp Val Lys Lys Gln
                  95                 100                 105

 Arg Ser Asp Pro Tyr Val Lys Ala Tyr Leu Leu Pro Asp Lys Gly
                 110                 115                 120

 Lys Met Gly Lys Lys Lys Thr Leu Val Val Lys Lys Thr Leu Asn
                 125                 130                 135

 Pro Val Tyr Asn Glu Ile Leu Arg Tyr Lys Ile Glu Lys Gln Ile
                 140                 145                 150

 Leu Lys Thr Gln Lys Leu Asn Leu Ser Ile Trp His Arg Asp Thr
                 155                 160                 165

 Phe Lys Arg Asn Ser Phe Leu Gly Glu Val Glu Leu Asp Leu Glu
                 170                 175                 180

 Thr Trp Asp Trp Asp Asn Lys Gln Asn Lys Gln Leu Arg Trp Tyr
                 185                 190                 195

 Pro Leu Lys Arg Lys Thr Ala Pro Val Ala Leu Glu Ala Glu Asn
                 200                 205                 210

 Arg Gly Glu Met Lys Leu Ala Leu Gln Tyr Val Pro Glu Pro Val
                 215                 220                 225

 Pro Gly Lys Lys Leu Pro Thr Thr Gly Glu Val His Ile Trp Val
                 230                 235                 240

 Lys Glu Cys Leu Asp Leu Pro Leu Leu Arg Gly Ser His Leu Asn
                 245                 250                 255

 Ser Phe Val Lys Cys Thr Ile Leu Pro Asp Thr Ser Arg Lys Ser
                 260                 265                 270

 Arg Gln Lys Thr Arg Ala Val Gly Lys Thr Thr Asn Pro Ile Phe
                 275                 280                 285

 Asn His Thr Met Val Tyr Asp Gly Phe Arg Pro Glu Asp Leu Met
                 290                 295                 300

 Glu Ala Cys Val Glu Leu Thr Val Trp Asp His Tyr Lys Leu Thr
                 305                 310                 315

 Asn Gln Phe Leu Gly Gly Leu Arg Ile Gly Phe Gly Thr Gly Lys
                 320                 325                 330

 Ser Tyr Gly Thr Glu Val Asp Trp Met Asp Ser Thr Ser Glu Glu
                 335                 340                 345

 Val Ala Leu Trp Glu Lys Met Val Asn Ser Pro Asn Thr Trp Ile
                 350                 355                 360

 Glu Ala Thr Leu Pro Leu Arg Met Leu Leu Ile Ala Lys Ile Ser
                 365                 370                 375

 Lys


<210> 4907
<211> 2158
<212> DNA
<213> Homo sapien

<400> 4907
 actagcgacc ggtgacctct ttttccccct tgcctggctc ctgtggtggc 50

 aggctgggca cgaggaccat gctgggccgg agcctccgag aagtttctgc 100

 ggcactgaaa caaggccaaa ttacaccaac agagctctgt caaaaatgtc 150

 tctctcttat caagaagacc aagtttctaa atgcctacat tactgtgtca 200

 gaagaggtgg ccttaaaaca agctgaagaa tcagaaaaga gatataagaa 250

 tggacagtca cttggggatt tagatggaat tcctattgca gtaaaagaca 300

 atttcagcac ttctggcatt gagacaacat gtgcatcaaa tatgctgaaa 350

 ggttatatac caccttataa tgctacagta gttcagaagt tgttggatca 400

 gggagctcta ctaatgggaa aaacaaattt agatgagttt gctatgggat 450

 ctgggagcac agatggtgta tttggaccag ttaaaaaccc ctggagttat 500

 tcaaaacaat atagagaaaa gaggaagcag aatccccaca gcgagaatga 550

 agattcagac tggctgataa ctggaggaag ctcaggtggg agtgcagctg 600

 ctgtatcggc gttcacatgc tacgcggctt taggatcaga tacaggagga 650

 tcgaccagaa atcctgctgc ccactgtggg cttgttggtt tcaaaccaag 700

 ctatggctta gtttcccgtc atggtctcat tcccctggtg aattcgatgg 750

 atgtgccagg aatcttaacc agatgtgtgg atgatgcagc aattgtgttg 800

 ggtgcactgg ccggacctga ccccagggac tctaccacag tacatgaacc 850

 tattaataaa ccattcatgc ttcccagttt ggcagatgtg agcaaactat 900

 gtataggaat tccaaaggta actttttcct ttcattactt tacagaaata 950

 ctgtcaagtc caatagagag cacagactag ggaggcggat tgggtgggtt 1000

 tgaatctctg ctctgccact tttattaatc atgtgagttg agtatgtgac 1050

 ttaatctctt ttagctcaat ttccccatct gtaaaatagg aataataaaa 1100

 atactgactt cagagaggtt tgtgaggatc aattagacag tcatgttaag 1150

 tctgtaaatt gtttctgtaa tgggcaagat agcaaatatt ttagattttg 1200

 tggaccatgc agtctttatc ataactgctt aactgccatt atagtgagaa 1250

 agcagccaca gacaatatgt aaatgaaaaa gtgtgtctct gttccaataa 1300

 aactttattt tcaaaaacca gctggcttgt cacatctggc ctatgggcca 1350

 tagtttgccc atccctaatg taaagaaagg actttagccc aaagccacaa 1400

 cttgcatagt aatgcctcaa aaaatgttaa catctttact gttattatta 1450

 ttactactgc atctattaca gtagcaattg agtaatgaat acatgaatgt 1500

 tataatgtta aattactaac cttttaaaaa tattaagcat tgcaatatat 1550

 taatacttta aatcttttag gaagataagt taccctgcag aataatgaag 1600

 tttcacaacc tcagcactgt tggtgtttgg ggctggtaat tgtttgttgt 1650

 gggagactgt cctgtgcatt gtaagatgtt tagtagcatc cctggcctct 1700

 acccctacat gcaagtagta ccccaccacc aaaaccacaa tcccacaacc 1750

 aaaaatgtct gcagacattg tcaagtgtct cctggttagg gaaaaggaga 1800

 caaaagtaac ccccaggtaa gaccactgct atagagaaat actaccttat 1850

 ttaaaatctt ccattaaggt aatatatgta aggccaggtg cgtacacctg 1900

 taatcccagc accttgggaa gccaaggcag gaggatcgct tgagatcagg 1950

 agtttgagac cagcctgggc aacatacaga gccctatgtc tacaaaaagt 2000

 tttaaaaaaa ttgtggggtg tggtggtgtg cacctgtggt cctagctgtt 2050

 tgggaggctg aggggggagg attgcttgag tccaggaggt tgagactgcc 2100

 gtgagccatg attgcaccac tgcactccac cctaggtgac agagcaagac 2150

 cctatctc 2158

<210> 4908
<211> 303
<212> PRT
<213> Homo sapien

<400> 4908
 Met Leu Gly Arg Ser Leu Arg Glu Val Ser Ala Ala Leu Lys Gln
   1               5                  10                  15

 Gly Gln Ile Thr Pro Thr Glu Leu Cys Gln Lys Cys Leu Ser Leu
                  20                  25                  30

 Ile Lys Lys Thr Lys Phe Leu Asn Ala Tyr Ile Thr Val Ser Glu
                  35                  40                  45

 Glu Val Ala Leu Lys Gln Ala Glu Glu Ser Glu Lys Arg Tyr Lys
                  50                  55                  60

 Asn Gly Gln Ser Leu Gly Asp Leu Asp Gly Ile Pro Ile Ala Val
                  65                  70                  75

 Lys Asp Asn Phe Ser Thr Ser Gly Ile Glu Thr Thr Cys Ala Ser
                  80                  85                  90

 Asn Met Leu Lys Gly Tyr Ile Pro Pro Tyr Asn Ala Thr Val Val
                  95                 100                 105

 Gln Lys Leu Leu Asp Gln Gly Ala Leu Leu Met Gly Lys Thr Asn
                 110                 115                 120

 Leu Asp Glu Phe Ala Met Gly Ser Gly Ser Thr Asp Gly Val Phe
                 125                 130                 135

 Gly Pro Val Lys Asn Pro Trp Ser Tyr Ser Lys Gln Tyr Arg Glu
                 140                 145                 150

 Lys Arg Lys Gln Asn Pro His Ser Glu Asn Glu Asp Ser Asp Trp
                 155                 160                 165

 Leu Ile Thr Gly Gly Ser Ser Gly Gly Ser Ala Ala Ala Val Ser
                 170                 175                 180

 Ala Phe Thr Cys Tyr Ala Ala Leu Gly Ser Asp Thr Gly Gly Ser
                 185                 190                 195

 Thr Arg Asn Pro Ala Ala His Cys Gly Leu Val Gly Phe Lys Pro
                 200                 205                 210

 Ser Tyr Gly Leu Val Ser Arg His Gly Leu Ile Pro Leu Val Asn
                 215                 220                 225

 Ser Met Asp Val Pro Gly Ile Leu Thr Arg Cys Val Asp Asp Ala
                 230                 235                 240

 Ala Ile Val Leu Gly Ala Leu Ala Gly Pro Asp Pro Arg Asp Ser
                 245                 250                 255

 Thr Thr Val His Glu Pro Ile Asn Lys Pro Phe Met Leu Pro Ser
                 260                 265                 270

 Leu Ala Asp Val Ser Lys Leu Cys Ile Gly Ile Pro Lys Val Thr
                 275                 280                 285

 Phe Ser Phe His Tyr Phe Thr Glu Ile Leu Ser Ser Pro Ile Glu
                 290                 295                 300

 Ser Thr Asp


<210> 4909
<211> 3019
<212> DNA
<213> Homo sapien

<400> 4909
 gcgccaccag ggcagcagcc gccgcagccg ccgccgctgg gcagaggagc 50

 cggagacgcg agcgggcgag gtggcggcgg cggcggagcg ggagcgggta 100

 ccgggcgcgg gcagagcgcg gcggcgcgga gacggggttt tgccatgttg 150

 acctggctgg tctcgaactc ctgaacgcaa gtgatccgcc tgcctcagcc 200

 tcccaaggtg ctgggattac aggcacgagc cactgtgcct ggcctcaact 250

 gttgcttctt ataaaggtgt gttccagaga acaagccttc agacatttgc 300

 tatattgacg ctgagctgtc aggggactca ggcttatgag gaggtattgt 350

 tacacaaaac agtgtctagt gaagacgaca agaaagaggg gaaaggatcg 400

 gaaaaagaag ctaaaatact atagaaaacc atgagatcta ttcgatcttt 450

 tgctaatgat gatcgccatg ttatggtgaa acattcaaca atctatccat 500

 ctccggagga acttgaagct gttcagaata tggtatctac tgttgaatgt 550

 gctcttaaac atgtctcaga ttggttggat gaaacaaata aaggcacaaa 600

 aacagagggt gagacagaag tgaagaaaga tgaggccgga gaaaactatt 650

 ccaaggatca aggtggtcgg acattgtgtg gtgtaatgag gattggcctg 700

 gttgcaaaag gcttgctgat taaagatgat atggacttgg agctggtttt 750

 aatgtgcaaa gacaaaccca cagagaccct gttaaataca gtcaaagata 800

 atcttcctat tcagattcag aaactcacag aagagaaata tcaagtggaa 850

 caatgtgtaa atgaggcatc tattataatt cggaatacaa aagagcccac 900

 gctaactttg aaggtgatac ttacctcacc tctaattagg gacgaattgg 950

 agaagaagga tggagaaaat gtttcgatga aagatcctcc ggacttattg 1000

 gacaggcaga aatgcctgaa cgccttggcg tctcttcgac atgccaaatg 1050

 gtttcaggca agggcaaatg gattaaaatc atgtgtaatt gtcctccgca 1100

 ttctgcgtga tttgtgcaac agagtcccca catgggcacc attgaaagga 1150

 tggccactag aacttatatg tgaaaagtct ataggtactt gtaatagacc 1200

 tttgggcgct ggggaggcct tgagacgagt aatggagtgt ttggcatctg 1250

 gaatactact tcctgggggt cctggtcttc atgatccttg tgagcgagac 1300

 ccaacagatg ctctgagcta tatgaccatc cagcaaaaag aagatattac 1350

 ccacagtgca cagcatgcac tcagactatc agcctttggt cagatttaca 1400

 aagtgctgga gatggacccc cttccatcta gtaagccttt tcagaagtat 1450

 tcctggtcag ttactgataa agaaggtgct gggtcttcag ctctaaagag 1500

 gccatttgaa gatggattag gggatgataa agaccccaac aagaagatga 1550

 aacgaaactt aaggaaaatt ctggatagta aagcaataga ccttatgaat 1600

 gcactaatga ggctaaatca gatcaggcct gggcttcagt ataagctcct 1650

 atctcagtct ggccccgttc atgccccagt cttcacaatg tctgtagatg 1700

 tggatggcac aacatatgaa gcctcaggac catccaagaa aacagcaaaa 1750

 cttcacgtag cggtgaaggt attgcaggca atgggatatc caacaggctt 1800

 tgatgcagat attgaatgta tgagttccga tgaaaaatca gataatgaaa 1850

 gtaaaaatga aacagtgtct tcaaactcaa gcaataatac tggaaattct 1900

 acaactgaaa cctccagtac cttagaggta agaactcagg gccctatcct 1950

 cacagcaagt ggcaaaaacc ctgtaatgga gctcaatgaa aaaagaagag 2000

 gtctcaagta tgaactcatc tcagagactg gtggaagcca tgacaagcgc 2050

 tttgtaatgg aggtagaagt agatggacag aaattcagag gcgcaggtcc 2100

 aaataagaaa gtggcaaagg cgagtgcagc tttagctgcc ttggagaaac 2150

 tgttttctgg acccaatgcg gcaaataata agaaaaagaa gattatccct 2200

 caggcaaagg gcgttgtgaa tacagctgtg tctgcagcag tccaagctgt 2250

 tcggggcaga ggaagaggaa ctctaacaag gggagctttt gttggggcga 2300

 cagctgctcc tggctacata gctccaggct atggaacacc atatggttac 2350

 agcacagctg cccctgccta tggtttaccc aagagaatgg ttctgttacc 2400

 cgttatgaaa tttccaacat atcctgttcc ccactactca ttcttttagc 2450

 aaatgacaga agctaattcc tattgaacaa caatacagta caacacagaa 2500

 tgttagagaa aaagcctttt tatcctgctt tctttgaaca catacttgat 2550

 caaaattatt tgtaaagaac atctttccta ctttttgatt ttaacaaatg 2600

 caaatttagt tctctaaaac ttgaaaaaaa aaagaaacca gttctgtgaa 2650

 aacggtacct catttctgga aaataactta taccagccct tctgttctag 2700

 ggaaataaaa gtctagcagt tcaaagttta agttttaaga gacgtatcag 2750

 attatgtaaa attaaatttg tgaaggatgt atagagtctc aaacactgat 2800

 cacaaataaa ctgctttgtt gtaacacaga gtactgcctg gttcctgatg 2850

 cagtcactga ttcttagttg attgatatgt atttgcccca gggcacttta 2900

 atttgggctg tagttatttt ttttaataca atagagactt ttcatttaac 2950

 tttaactttg taaatattga agtgtgtaat aaagccaata aaatatgggt 3000

 ttgaaaaaaa aaaaaaaaa 3019

<210> 4910
<211> 672
<212> PRT
<213> Homo sapien

<400> 4910
 Met Arg Ser Ile Arg Ser Phe Ala Asn Asp Asp Arg His Val Met
   1               5                  10                  15

 Val Lys His Ser Thr Ile Tyr Pro Ser Pro Glu Glu Leu Glu Ala
                  20                  25                  30

 Val Gln Asn Met Val Ser Thr Val Glu Cys Ala Leu Lys His Val
                  35                  40                  45

 Ser Asp Trp Leu Asp Glu Thr Asn Lys Gly Thr Lys Thr Glu Gly
                  50                  55                  60

 Glu Thr Glu Val Lys Lys Asp Glu Ala Gly Glu Asn Tyr Ser Lys
                  65                  70                  75

 Asp Gln Gly Gly Arg Thr Leu Cys Gly Val Met Arg Ile Gly Leu
                  80                  85                  90

 Val Ala Lys Gly Leu Leu Ile Lys Asp Asp Met Asp Leu Glu Leu
                  95                 100                 105

 Val Leu Met Cys Lys Asp Lys Pro Thr Glu Thr Leu Leu Asn Thr
                 110                 115                 120

 Val Lys Asp Asn Leu Pro Ile Gln Ile Gln Lys Leu Thr Glu Glu
                 125                 130                 135

 Lys Tyr Gln Val Glu Gln Cys Val Asn Glu Ala Ser Ile Ile Ile
                 140                 145                 150

 Arg Asn Thr Lys Glu Pro Thr Leu Thr Leu Lys Val Ile Leu Thr
                 155                 160                 165

 Ser Pro Leu Ile Arg Asp Glu Leu Glu Lys Lys Asp Gly Glu Asn
                 170                 175                 180

 Val Ser Met Lys Asp Pro Pro Asp Leu Leu Asp Arg Gln Lys Cys
                 185                 190                 195

 Leu Asn Ala Leu Ala Ser Leu Arg His Ala Lys Trp Phe Gln Ala
                 200                 205                 210

 Arg Ala Asn Gly Leu Lys Ser Cys Val Ile Val Leu Arg Ile Leu
                 215                 220                 225

 Arg Asp Leu Cys Asn Arg Val Pro Thr Trp Ala Pro Leu Lys Gly
                 230                 235                 240

 Trp Pro Leu Glu Leu Ile Cys Glu Lys Ser Ile Gly Thr Cys Asn
                 245                 250                 255

 Arg Pro Leu Gly Ala Gly Glu Ala Leu Arg Arg Val Met Glu Cys
                 260                 265                 270

 Leu Ala Ser Gly Ile Leu Leu Pro Gly Gly Pro Gly Leu His Asp
                 275                 280                 285

 Pro Cys Glu Arg Asp Pro Thr Asp Ala Leu Ser Tyr Met Thr Ile
                 290                 295                 300

 Gln Gln Lys Glu Asp Ile Thr His Ser Ala Gln His Ala Leu Arg
                 305                 310                 315

 Leu Ser Ala Phe Gly Gln Ile Tyr Lys Val Leu Glu Met Asp Pro
                 320                 325                 330

 Leu Pro Ser Ser Lys Pro Phe Gln Lys Tyr Ser Trp Ser Val Thr
                 335                 340                 345

 Asp Lys Glu Gly Ala Gly Ser Ser Ala Leu Lys Arg Pro Phe Glu
                 350                 355                 360

 Asp Gly Leu Gly Asp Asp Lys Asp Pro Asn Lys Lys Met Lys Arg
                 365                 370                 375

 Asn Leu Arg Lys Ile Leu Asp Ser Lys Ala Ile Asp Leu Met Asn
                 380                 385                 390

 Ala Leu Met Arg Leu Asn Gln Ile Arg Pro Gly Leu Gln Tyr Lys
                 395                 400                 405

 Leu Leu Ser Gln Ser Gly Pro Val His Ala Pro Val Phe Thr Met
                 410                 415                 420

 Ser Val Asp Val Asp Gly Thr Thr Tyr Glu Ala Ser Gly Pro Ser
                 425                 430                 435

 Lys Lys Thr Ala Lys Leu His Val Ala Val Lys Val Leu Gln Ala
                 440                 445                 450

 Met Gly Tyr Pro Thr Gly Phe Asp Ala Asp Ile Glu Cys Met Ser
                 455                 460                 465

 Ser Asp Glu Lys Ser Asp Asn Glu Ser Lys Asn Glu Thr Val Ser
                 470                 475                 480

 Ser Asn Ser Ser Asn Asn Thr Gly Asn Ser Thr Thr Glu Thr Ser
                 485                 490                 495

 Ser Thr Leu Glu Val Arg Thr Gln Gly Pro Ile Leu Thr Ala Ser
                 500                 505                 510

 Gly Lys Asn Pro Val Met Glu Leu Asn Glu Lys Arg Arg Gly Leu
                 515                 520                 525

 Lys Tyr Glu Leu Ile Ser Glu Thr Gly Gly Ser His Asp Lys Arg
                 530                 535                 540

 Phe Val Met Glu Val Glu Val Asp Gly Gln Lys Phe Arg Gly Ala
                 545                 550                 555

 Gly Pro Asn Lys Lys Val Ala Lys Ala Ser Ala Ala Leu Ala Ala
                 560                 565                 570

 Leu Glu Lys Leu Phe Ser Gly Pro Asn Ala Ala Asn Asn Lys Lys
                 575                 580                 585

 Lys Lys Ile Ile Pro Gln Ala Lys Gly Val Val Asn Thr Ala Val
                 590                 595                 600

 Ser Ala Ala Val Gln Ala Val Arg Gly Arg Gly Arg Gly Thr Leu
                 605                 610                 615

 Thr Arg Gly Ala Phe Val Gly Ala Thr Ala Ala Pro Gly Tyr Ile
                 620                 625                 630

 Ala Pro Gly Tyr Gly Thr Pro Tyr Gly Tyr Ser Thr Ala Ala Pro
                 635                 640                 645

 Ala Tyr Gly Leu Pro Lys Arg Met Val Leu Leu Pro Val Met Lys
                 650                 655                 660

 Phe Pro Thr Tyr Pro Val Pro His Tyr Ser Phe Phe
                 665                 670

<210> 4911
<211> 3857
<212> DNA
<213> Homo sapien

<400> 4911
 agtaacgcct tctccaagtg gatggcgggg tggacacgcg tcccggcgcc 50

 ccgggctccc tgggatatgt agttcgcgac aggacgagcg gaaatactgc 100

 caggatttta ccacctctcg cccatttatt tacttctcgg tcaccgcttt 150

 cgggggacag ataaacacca cagatgccca tcaaaggggc gcacgggtct 200

 ggaggcgcag ctcaggtttt tgcgttggtc accctgccct ccgcacgtgg 250

 agagggcagg cataaagcac cttgaaagga aggtgctgtc aatgctatcc 300

 gacgacctgt cgccgggcac cgcagcatcc tcgctcgctc cgatgggacg 350

 agggacgccg gccccagggt aacaggaggc gcctcgccgg ccgcgcgctg 400

 gatgctgtga tccaggtccg gagccgggtt ccgccgcggc cgcagcgacc 450

 cgaccccacc cgacaggcca gaggaatcag tttagacttg aaattcagtt 500

 tttcctgaaa ctgatcagaa gttagtgaca ccttgattgg atccgttttt 550

 ctgtcaggag ctcattttgc agctctcaag cttttatagc atgctgtaaa 600

 caattgtcaa agttgtttat caagaaacag atagagttgc aacttgtttc 650

 tagtaataga aacttttaca ctgcattcaa tgcctaacgt tgcagaaaca 700

 gaaaggtcaa atgattctgg aaatggtgag cacaaatctg agagaaagtc 750

 acctgaagag aatctacaag gtgctgtaaa atctttctgc acaagtgcct 800

 caggagcacc cttgggtccc aaaggagatg gtcattatcc atggagttgt 850

 ccagtgactc atacacggga aaaaatttat gccatctgtt cggactatgc 900

 ctttctcaac caggcgacct caatctataa aactccaaat ccatcccgct 950

 ctccttgcct ccctgatagt acctctttat ctgctggaaa taattcatca 1000

 agatacattg gtatcccgac tagtacatcg gaaattatct acaatgaaga 1050

 aaatagcttg gaaaacttat ccaacagcct gggcaagcta cctctcgcat 1100

 gggaaattga taaatctgaa tttgatgggg tgaccacaaa ttcgaaacac 1150

 aaatcaggca atgcaaagaa acaagtttcc aagagaaaaa cttcagataa 1200

 aaagggaaga tatcagaagg aatgtcctca gcattctcct cttgaagata 1250

 ttaaacagcg gaaagtatta gacctcagac gatggtactg cataagccga 1300

 ccacagtata agacttcttg tggcatctct tcattaattt cttgttggaa 1350

 tttcttatac agcacaatgg gagctggaaa ccttccacct attacccaag 1400

 aagaagcttt acatattctg ggctttcaac ctccatttga agatattagg 1450

 tttggtcctt tcacggggaa tacaacactt atgaggtggt ttagacaaat 1500

 taatgaccac ttccatgtaa aaggatgctc ttatgttcta tataagcctc 1550

 atgggaagaa taaaacagca ggagaaactg cttcaggggc cctgtcaaag 1600

 ttaacccgtg gattgaaaga tgaatcgctg gcttatatct atcattgcca 1650

 aaatcattat ttttgtccaa ttggcttcga agcaacccct gttaaagcta 1700

 ataaagcatt cagcagggga cctctctcac cacaggaagt tgaatattgg 1750

 atcttaattg gagaatcaag tagaaaacat cctgccattc actgtaaaaa 1800

 atgggcagat attgttactg atctaaacac tcaaaatcca gaatacctgg 1850

 atatccggca cttagagagg ggactgcagt atagaaaaac aaagaaggtt 1900

 gggggaaatt tgcattgcat catagcattc cagagactta actggcaaag 1950

 atttggcctt tggaactttc catttggaac cattagacaa gaatcacaac 2000

 ctccaacaca tgcccaggga attgccaaat ctgagagtga agacaatatt 2050

 tccaagaagc agcatgggcg tctgggccgg tctttcagtg ctagtttcca 2100

 tcaggactcg gcatggaaaa agatgtctag tatccatgag agaaggaaca 2150

 gtggttacca gggttacagt gattacgatg ggaatgattg actatgcttg 2200

 ctactgaaca gctggcatta tatatgaaac tgctatatac aggactgtat 2250

 aaagacagta gaagatttta gtaagcctac attaaatagg agcagatctt 2300

 gtggtataaa aaataacctt gtagttctcc agatactaag cttgtatatg 2350

 attatggtgg gtgatttcag atatataagc agataagcac agattattgt 2400

 cctttcaagt taagagtata taatctggac agaaaatttc acaaaattca 2450

 ataaaattac aactgttgtc taaataagtg aaacacaaat tcacttaata 2500

 gcatcaagat ttgaaatact taagcatgaa gtgactttta taatgactcg 2550

 atccctagac atttgttaca gatagtttta tgcctaagac caagatgtaa 2600

 agtaccatct gcccttaaaa aaaattgggg ctgtcaattt ctagttttca 2650

 ctcatggtta acacgcattt aaaattattt catgagtcta gtagttcttt 2700

 gatttatagc aggatcttgc ttgcctcatt tgtttcctgg ttatgttctt 2750

 aggattctga ctaagaggca aaagagaaaa gactcaagaa actgatcctg 2800

 gagatcgaga ccatcctggc taacatggtg aaaccccgtc tctactaaac 2850

 atacaaaaaa ttagccgggt gtagtggtgg gcacctgtag tcctagctac 2900

 tcgagaggct gaggcaggag aatggcgtga acccgggagg tggagcttgc 2950

 agtgagcgga gatcgcgcca ctgcactcca gcctgggcga cagggcaaga 3000

 ctctgtctca aaaaaaaaaa aaaaaaaaaa gacggatcct tttttttggt 3050

 gcaaatgggt gacttagtgc attgattcag atttttaaaa tttcttgatg 3100

 tggtttgtaa taatcaaata ttgacaagaa ccttaggtct cgaaagactt 3150

 ttataagtct agatgacgtt tgccttaggg gtaaagtaaa agaacaattg 3200

 gcaccttaag tttctatacc caaggttatc tgtgaaatga gatctcctga 3250

 tatttgattg ctttctcagt atggagtcat atgttgataa cagtactgaa 3300

 gatgcataag aaatgcccaa gtcactcaga ggacaactac ccatattcca 3350

 gactctgagc tgtttccttt ttaaaaatca tatagacaat tagctgtttg 3400

 aagtgagtat taaatatttc agaagtgtga atttcatgta tttgagctcc 3450

 tctagttgct gttggttttt cttctgctgc caacctgtga ctcacaaatg 3500

 actaggatct cttgttcttt aattttaggg tcttgttcca ggactcaaat 3550

 cagtaacttg gtgattacaa ggtgctgaat gtgttggtaa ccatatcgca 3600

 atacacctca aggaaaaggt tcagattttt atttttaaaa tattttcatt 3650

 tttttcttga attttatatc cgtttgttca ctcgtacatg cctagcctac 3700

 agaaggggat atatattatg aaatggtcat ttttctgaag agaatatttt 3750

 gcttgaaatg caaaggactg aaagagattt gtaggttgtt gattttgtta 3800

 cttcatactg gaacttttaa aaagatttca tcaaataaag ttttgttttc 3850

 tactttt 3857

<210> 4912
<211> 503
<212> PRT
<213> Homo sapien

<400> 4912
 Met Pro Asn Val Ala Glu Thr Glu Arg Ser Asn Asp Ser Gly Asn
   1               5                  10                  15

 Gly Glu His Lys Ser Glu Arg Lys Ser Pro Glu Glu Asn Leu Gln
                  20                  25                  30

 Gly Ala Val Lys Ser Phe Cys Thr Ser Ala Ser Gly Ala Pro Leu
                  35                  40                  45

 Gly Pro Lys Gly Asp Gly His Tyr Pro Trp Ser Cys Pro Val Thr
                  50                  55                  60

 His Thr Arg Glu Lys Ile Tyr Ala Ile Cys Ser Asp Tyr Ala Phe
                  65                  70                  75

 Leu Asn Gln Ala Thr Ser Ile Tyr Lys Thr Pro Asn Pro Ser Arg
                  80                  85                  90

 Ser Pro Cys Leu Pro Asp Ser Thr Ser Leu Ser Ala Gly Asn Asn
                  95                 100                 105

 Ser Ser Arg Tyr Ile Gly Ile Pro Thr Ser Thr Ser Glu Ile Ile
                 110                 115                 120

 Tyr Asn Glu Glu Asn Ser Leu Glu Asn Leu Ser Asn Ser Leu Gly
                 125                 130                 135

 Lys Leu Pro Leu Ala Trp Glu Ile Asp Lys Ser Glu Phe Asp Gly
                 140                 145                 150

 Val Thr Thr Asn Ser Lys His Lys Ser Gly Asn Ala Lys Lys Gln
                 155                 160                 165

 Val Ser Lys Arg Lys Thr Ser Asp Lys Lys Gly Arg Tyr Gln Lys
                 170                 175                 180

 Glu Cys Pro Gln His Ser Pro Leu Glu Asp Ile Lys Gln Arg Lys
                 185                 190                 195

 Val Leu Asp Leu Arg Arg Trp Tyr Cys Ile Ser Arg Pro Gln Tyr
                 200                 205                 210

 Lys Thr Ser Cys Gly Ile Ser Ser Leu Ile Ser Cys Trp Asn Phe
                 215                 220                 225

 Leu Tyr Ser Thr Met Gly Ala Gly Asn Leu Pro Pro Ile Thr Gln
                 230                 235                 240

 Glu Glu Ala Leu His Ile Leu Gly Phe Gln Pro Pro Phe Glu Asp
                 245                 250                 255

 Ile Arg Phe Gly Pro Phe Thr Gly Asn Thr Thr Leu Met Arg Trp
                 260                 265                 270

 Phe Arg Gln Ile Asn Asp His Phe His Val Lys Gly Cys Ser Tyr
                 275                 280                 285

 Val Leu Tyr Lys Pro His Gly Lys Asn Lys Thr Ala Gly Glu Thr
                 290                 295                 300

 Ala Ser Gly Ala Leu Ser Lys Leu Thr Arg Gly Leu Lys Asp Glu
                 305                 310                 315

 Ser Leu Ala Tyr Ile Tyr His Cys Gln Asn His Tyr Phe Cys Pro
                 320                 325                 330

 Ile Gly Phe Glu Ala Thr Pro Val Lys Ala Asn Lys Ala Phe Ser
                 335                 340                 345

 Arg Gly Pro Leu Ser Pro Gln Glu Val Glu Tyr Trp Ile Leu Ile
                 350                 355                 360

 Gly Glu Ser Ser Arg Lys His Pro Ala Ile His Cys Lys Lys Trp
                 365                 370                 375

 Ala Asp Ile Val Thr Asp Leu Asn Thr Gln Asn Pro Glu Tyr Leu
                 380                 385                 390

 Asp Ile Arg His Leu Glu Arg Gly Leu Gln Tyr Arg Lys Thr Lys
                 395                 400                 405

 Lys Val Gly Gly Asn Leu His Cys Ile Ile Ala Phe Gln Arg Leu
                 410                 415                 420

 Asn Trp Gln Arg Phe Gly Leu Trp Asn Phe Pro Phe Gly Thr Ile
                 425                 430                 435

 Arg Gln Glu Ser Gln Pro Pro Thr His Ala Gln Gly Ile Ala Lys
                 440                 445                 450

 Ser Glu Ser Glu Asp Asn Ile Ser Lys Lys Gln His Gly Arg Leu
                 455                 460                 465

 Gly Arg Ser Phe Ser Ala Ser Phe His Gln Asp Ser Ala Trp Lys
                 470                 475                 480

 Lys Met Ser Ser Ile His Glu Arg Arg Asn Ser Gly Tyr Gln Gly
                 485                 490                 495

 Tyr Ser Asp Tyr Asp Gly Asn Asp
                 500

<210> 4913
<211> 2883
<212> DNA
<213> Homo sapien

<400> 4913
 aacagatctt catgaatgtc gctatctttg aggatgaagt ttttgctgga 50

 gttaccacac accaggaact ctttccacac agcctgctga gtgtgattgc 100

 caacttcatc cctttctctg atctcaacca gagtccacgg aacatgtacc 150

 aatgccagat gggtaagcaa actatgggct ttccacttct cacttatcaa 200

 gaccgatcgg ataacaaact gtatcgtctt cagactcctc agagtccctt 250

 ggtgagaccc tccatgtatg attattatga catggataac tatccaattg 300

 ggaccaatgc catcgttgct gtgatttctt acactggcta tgatatggaa 350

 gatgccatga ttgtgaataa ggcctcttgg gaacgaggct ttgcccatgg 400

 aagtgtctac aagtctgagt tcatagacct ctctgaaaaa attaaacaag 450

 gagatagtag cctggtgttt ggcatcaaac ctggtgaccc acgcgttctg 500

 cagaagttag atgacgatgg attgccgttt ataggagcaa aactgcagta 550

 cggagatccg tattacagct acctcaacct caacaccggg gaaagttttg 600

 tgatgtacta taagagtaaa gaaaattgtg ttgtggataa catcaaagtg 650

 tgcagtaatg acactgggag tggaaaattc aagtgtgttt gcatcactat 700

 gagagtgcct cggaacccaa ctatcggaga taaatttgcc agtcgccatg 750

 ggcagaaggg cattttaagc agattgtggc cggctgagga catgcctttt 800

 actgagagtg ggatggtccc agacattctg ttcaatcccc atggttttcc 850

 atcccgcatg accattggga tgttaattga gagtatggcc gggaagtctg 900

 cagctttgca tggtctctgc catgatgcta cacccttcat cttctcagag 950

 gagaactcgg ccttagaata ctttggtgag atgttaaagg ctgctggcta 1000

 caatttctat ggcaccgaga ggttatatag tggcatcagt gggctagaac 1050

 tggaagcaga catcttcata ggagtggttt attatcagcg cttacgccat 1100

 atggtctcag acaaatttca agtaaggaca actggagccc gagacagagt 1150

 caccaaccag cctattgggg gaagaaatgt ccagggtgga atccgttttg 1200

 gggagatgga acgggatgcg cttttagctc atggtacatc ttttctcctt 1250

 catgaccgcc tcttcaactg ctcagatcgg tcggtagccc atgtgtgtga 1300

 agtgtggcag tttactctct ccactgttgg agaagccacc cccttcttgg 1350

 tctgccatgc gcaacagaaa atacaactgt actctgtgta gtcgcagtga 1400

 cactatcgat actgtttctg tgccttatgt ttttcggtat tttgtagctg 1450

 aactggcagc tatgaacatc aaagtgaaac tggatgttgt ttaacttgat 1500

 gttgaccttt tggattaagg ggactatcag attaaagcaa aatgtaattt 1550

 taattcaatg aagatatcat taccaggtta ctcttgagat ttttcaacgg 1600

 tgttagaact ctcaaccaag acctgaaaac caagtatgca aggtttctga 1650

 atctctctgg tagattaact attgacaatg attttctgtt atctttgttc 1700

 aaaaagttca tgtcttctca aaatatgaaa tattgataaa tggaagagca 1750

 tacggtgaca agtctccttt ccaaccccag gttccctaca ccctgctctc 1800

 agcaggcagt gagtgtcaca cacctgttaa tccatcttga gcaggacagt 1850

 actatacaaa tagaatgcaa gctgtaatgt aattttatat tttcttatag 1900

 ccacgttgaa gtaaaaacaa acaggtacag tgttttttac cagctttata 1950

 gaagtacagt tgttacatat ttaatgaata caatttgatg ggtctgacta 2000

 tatgcacaca cctttgatac catcaccaca atcagggtaa taaacatacc 2050

 tgtcatctcc acaagtttcc tcctgcccct ttgttttttg ctttttggtt 2100

 gctgttgagt ttttgttttg tcttctgtgg taagaacact taactcaaga 2150

 cctaccctct taacaaatct ttaagtgcac gatatagtat tgttaattcc 2200

 aggcaccatg ttgtacaaca gatctttaga ccttacttgt cttgcataac 2250

 tgaagcttta tacctgttga acaactctcc atttccctgg cccctagcaa 2300

 ccacccttct accctgtttc tatgagtttg actattacag atatctcata 2350

 tagtgggatc atgcaatatt tgtcctgtga ctggcttatt tcacttagca 2400

 tagtgaaata agattcatcc attttggaag ccaggcatgg tgctgtgcat 2450

 ctatagtccc tgctatttga gaggctgagg tgggaggatc atttgagtgc 2500

 aggagttcaa ggacagcctg ggtaatatag gaagaccctg tcttgaagac 2550

 cctgacctca agtgatccac ccacctcggc ctccgaaagt gctaggatta 2600

 caggtgtgag ccactgtgcc tggcctccgg tgagtatttt atatttagtc 2650

 tacacttcca tacttggctt ttttctgctt ttatgttgat ctgctttcat 2700

 agcagtgtgt agagtgccac ttatgttttc tttcttgtgt acagtatttt 2750

 attgtatgga tttaccatcc cctgtgtatt taagttgttc cattctttgg 2800

 ccattataac ttttttctgc aaatattctg gtgacttatc tttggccatt 2850

 ataaactgtt gataataaaa aaaaaaaaaa aaa 2883

<210> 4914
<211> 459
<212> PRT
<213> Homo sapien

<400> 4914
 Met Asn Val Ala Ile Phe Glu Asp Glu Val Phe Ala Gly Val Thr
   1               5                  10                  15

 Thr His Gln Glu Leu Phe Pro His Ser Leu Leu Ser Val Ile Ala
                  20                  25                  30

 Asn Phe Ile Pro Phe Ser Asp Leu Asn Gln Ser Pro Arg Asn Met
                  35                  40                  45

 Tyr Gln Cys Gln Met Gly Lys Gln Thr Met Gly Phe Pro Leu Leu
                  50                  55                  60

 Thr Tyr Gln Asp Arg Ser Asp Asn Lys Leu Tyr Arg Leu Gln Thr
                  65                  70                  75

 Pro Gln Ser Pro Leu Val Arg Pro Ser Met Tyr Asp Tyr Tyr Asp
                  80                  85                  90

 Met Asp Asn Tyr Pro Ile Gly Thr Asn Ala Ile Val Ala Val Ile
                  95                 100                 105

 Ser Tyr Thr Gly Tyr Asp Met Glu Asp Ala Met Ile Val Asn Lys
                 110                 115                 120

 Ala Ser Trp Glu Arg Gly Phe Ala His Gly Ser Val Tyr Lys Ser
                 125                 130                 135

 Glu Phe Ile Asp Leu Ser Glu Lys Ile Lys Gln Gly Asp Ser Ser
                 140                 145                 150

 Leu Val Phe Gly Ile Lys Pro Gly Asp Pro Arg Val Leu Gln Lys
                 155                 160                 165

 Leu Asp Asp Asp Gly Leu Pro Phe Ile Gly Ala Lys Leu Gln Tyr
                 170                 175                 180

 Gly Asp Pro Tyr Tyr Ser Tyr Leu Asn Leu Asn Thr Gly Glu Ser
                 185                 190                 195

 Phe Val Met Tyr Tyr Lys Ser Lys Glu Asn Cys Val Val Asp Asn
                 200                 205                 210

 Ile Lys Val Cys Ser Asn Asp Thr Gly Ser Gly Lys Phe Lys Cys
                 215                 220                 225

 Val Cys Ile Thr Met Arg Val Pro Arg Asn Pro Thr Ile Gly Asp
                 230                 235                 240

 Lys Phe Ala Ser Arg His Gly Gln Lys Gly Ile Leu Ser Arg Leu
                 245                 250                 255

 Trp Pro Ala Glu Asp Met Pro Phe Thr Glu Ser Gly Met Val Pro
                 260                 265                 270

 Asp Ile Leu Phe Asn Pro His Gly Phe Pro Ser Arg Met Thr Ile
                 275                 280                 285

 Gly Met Leu Ile Glu Ser Met Ala Gly Lys Ser Ala Ala Leu His
                 290                 295                 300

 Gly Leu Cys His Asp Ala Thr Pro Phe Ile Phe Ser Glu Glu Asn
                 305                 310                 315

 Ser Ala Leu Glu Tyr Phe Gly Glu Met Leu Lys Ala Ala Gly Tyr
                 320                 325                 330

 Asn Phe Tyr Gly Thr Glu Arg Leu Tyr Ser Gly Ile Ser Gly Leu
                 335                 340                 345

 Glu Leu Glu Ala Asp Ile Phe Ile Gly Val Val Tyr Tyr Gln Arg
                 350                 355                 360

 Leu Arg His Met Val Ser Asp Lys Phe Gln Val Arg Thr Thr Gly
                 365                 370                 375

 Ala Arg Asp Arg Val Thr Asn Gln Pro Ile Gly Gly Arg Asn Val
                 380                 385                 390

 Gln Gly Gly Ile Arg Phe Gly Glu Met Glu Arg Asp Ala Leu Leu
                 395                 400                 405

 Ala His Gly Thr Ser Phe Leu Leu His Asp Arg Leu Phe Asn Cys
                 410                 415                 420

 Ser Asp Arg Ser Val Ala His Val Cys Glu Val Trp Gln Phe Thr
                 425                 430                 435

 Leu Ser Thr Val Gly Glu Ala Thr Pro Phe Leu Val Cys His Ala
                 440                 445                 450

 Gln Gln Lys Ile Gln Leu Tyr Ser Val
                 455

<210> 4915
<211> 902
<212> DNA
<213> Homo sapien

<400> 4915
 gactcttacc tacttcgggg cccactttgc tgtcatccgc cgagcgtccc 50

 tggagaagaa cccgtaccag gctgtgcacc aatgggcctt ctctgcgggg 100

 ttgagcctgg tgggcctcct gactctggga gccgtgctga gcgctgcagc 150

 caccgtgagg gaggcccagg gcctcatggc agggggcttc ctgtgcttct 200

 ccctggcgtt ctgtgcacag gtgcaggtgg tgttctggag actccacagc 250

 cccacccagg tggaggacgc catgctggac acctacgacc tggtatatga 300

 gcaggcgatg aaaggtacgt cccacgtccg gcggcaggag ctggcggcca 350

 tccaggacgt gtttctgtgc tgtgggaaga agtctccttt cagccgtctg 400

 gggagcacag aggctgacct gtgtcaggga gaggaggcgg cgagagagga 450

 ctgccttcag ggcatccgga gcttcctgag gacacaccag caggtcgcct 500

 ccagcctgac cagcatcggc ctggccctca cggtgtccgc cttgctcttc 550

 agctccttcc tgtggtttgc catccgctgt ggctgcagct tggaccgcaa 600

 gggcaaatac accctgaccc cacgctctcc agggcagaag tcgcggtggg 650

 ctcagtgggt gccctgagcg gggtctctca gactgacgtc aggccttggt 700

 gggctgcact ctcacctgga ggctccgggg aagcatctgc ctccaggacc 750

 attcaggctg ttgacaagtc aactcctcat ggctgtagga ctgaggttcc 800

 caagtccttg tccctggtcc tgtggtccct ccaccttcaa accagcaatg 850

 gtgcattgag caaattgtgg tcaaatatac atcacatcaa atttaccatc 900

 tt 902

<210> 4916
<211> 3873
<212> DNA
<213> Homo sapien

<400> 4916
 atctgctggc atttcctgca gccaggcccg cgccgccagt ggagcccccg 50

 cgcgcccggc cggcccggag caccgagctc gcggcacggt aggagaagcc 100

 cccgagcgcc cacagcatga aggaggaggc cttcctccgg cgccgcttct 150

 ccctgtgtcc accttcctcc acccctcaga aagtcgaccc ccggaagctc 200

 acccggaact tgctcctcag cggagacaat gagctctacc cactcagccc 250

 agggaaggac atggagccca acggcccgtc gctgcccagg gatgaagggc 300

 ccccgacccc aagctctgcc acgaaggtgc caccggcaga gtacaggctg 350

 tgcaacgggt cagacaagga atgtgtgtcc cccaccgcca gggtcaccaa 400

 gaaggagact ctcaaggcgc agaaggagaa ctaccggcag gagaagaagc 450

 gcgccacacg gcagctgctc agcgctctga cagaccccag cgtggtcatc 500

 atggctgaca gcctgaagat ccgcggcacc ctgaagagct ggaccaagct 550

 gtggtgcgtg ctgaagccgg gggtgctgct catctacaag acgcccaagg 600

 tgggccagtg ggtgggcacg gtgctgctgc actgctgcga gctcatcgag 650

 cggccctcca agaaggacgg cttctgcttc aagctcttcc acccgctgga 700

 tcagtccgtc tgggccgtga agggccccaa aggtgagagc gtgggctcca 750

 tcacacagcc cctgcccagc agctacctga tcttcagggc cgcctccgag 800

 tcagatggtc gctgctggct ggacgccctg gagctggccc tgcgctgctc 850

 tagcctactg agactgggca cctgcaagcc gggccgagac ggggagccag 900

 ggacctcgcc agacgcatca ccctcatcgc tctgtgggct gccagcctca 950

 gccaccgtcc acccagacca agacctgttc ccactgaacg ggtcttccct 1000

 ggagaacgat gcattctcag acaagtcgga gagagagaac cctgaggagt 1050

 cagataccga gacccaggac catagccgga agacggagag tggcagcgac 1100

 cagtcagaga cccctggggc cccggtgcgg agagggacca cctatgtgga 1150

 gcaggtccag gaggagctgg gggagctggg cgaggcgtcc caggtggaga 1200

 cagtgtcaga ggagaacaag agtctgatgt ggaccctgct gaagcagcta 1250

 cggccaggca tggacctgtc ccgcgtggtg ctacccacgt tcgtactgga 1300

 gccgcgctcc ttcctgaaca agctctccga ctactactac cacgcagacc 1350

 tgctctccag ggctgcggtg gaggaggatg cctacagccg catgaagctg 1400

 gtgctgcggt ggtacctgtc tggcttctac aagaagccca agggaatcaa 1450

 gaagccgtac aaccccatcc tgggggagac cttccgctgc tgctggttcc 1500

 acccgcagac tgacagccgc acattctaca tagcagagca ggtgtcccac 1550

 cacccgcccg tgtctgcctt ccacgtcagc aaccggaagg acggcttctg 1600

 catcagtggc agcatcacag ccaagtccag gttttatggg aactcgctgt 1650

 cggcgctgct ggacggcaaa gccacgctca ccttcctgaa ccgagccgag 1700

 gattacaccc ttaccatgcc ctacgcccac tgcaaaggaa tcctgtatgg 1750

 cacgatgacc ctggagctgg gtgggaaggt caccatcgag tgtgcgaaga 1800

 acaacttcca ggcccagctg gaattcaaac tcaagccctt cttcgggggt 1850

 agcaccagca tcaaccagat ctcgggaaag atcacgtcgg gagaggaagt 1900

 cctggcgagc ctcagtggcc actgggacag ggacgtgttt atcaaggagg 1950

 aagggagcgg aagcagtgcg cttttctgga ccccgagcgg ggaggtccgc 2000

 agacagaggc tgaggcagca cacggtgccg ctggaggagc agacggagct 2050

 ggagtccgag aggctctggc agcacgtcac cagggccatc agcaagggcg 2100

 accagcacag ggccacacag gagaagtttg cactggagga ggcacagcgg 2150

 cagcgggccc gtgagcggca ggagagcctc atgccctgga agccgcagct 2200

 gttccacctg gaccccatca cccaggagtg gcactaccga tacgaggacc 2250

 acagcccctg ggaccccctg aaggacatcg cccagtttga gcaagacggg 2300

 atcctgcgga ccttgcagca ggaggccgtg gcccgccaga ccaccttcct 2350

 gggcagccca gggcccaggc acgagaggtc tggcccagac cagcggcttc 2400

 gcaaggccag cgaccagccc tccggccaca gccaggccac ggagagcagc 2450

 ggatccacgc ctgagtcctg cccagagctc tcagacgagg agcaggatgg 2500

 tgactttgtc cctggcggtg agagcccatg ccctcggtgc aggaaggagg 2550

 cgcggcggct gcaggccctg cacgaggcca tcctctccat ccgagaggcc 2600

 cagcaggagc tgcacaggca cctctcggcc atgctgagct ccacggcacg 2650

 ggcagcacag gcaccgaccc caggcctcct gcagagcccc cgatcctggt 2700

 tcctgctctg cgtgttcctg gcgtgtcagc tgttcattaa ccacatcctc 2750

 aaataggagc cctgggggca gagctcctgg ccagtcccga gccctccctc 2800

 ccaggcaccc agcactttaa gcctgctcca tggaggcaga gaggcccggc 2850

 aagcacagcc actgtgacgg ggagtccagg cgcaggaggg acccggggcc 2900

 acaaggcgct gcgggcccag gtgtgctggg cccctctcag gggcactggc 2950

 ctctctgcag ggccttccgc ccagcgctgg ccttaatgct aaagccaaat 3000

 gcagcttctg ctgtgcgacg cactcctggc catcttgccg tgtcaccccc 3050

 tgtccggcct ccacttgcca tgggggatgg atggatttag ggtgggaggg 3100

 cctgtggggg ccctggacag tcacacccca gcagcagtga gtgggcaggt 3150

 ttggaggagc agccagggag ccccgagtgg cccaggagtc cccccacaca 3200

 cagatgcata ggcctgcctt ccggagaccc tgtccacatt gccgggacca 3250

 ccctggtggg gccactggtg ggtgccaggg acaggttagg gccactctgg 3300

 ggaaggcatt ttggtttttt attccacgct gtgctgtttg gatgggagcc 3350

 ccacagaggc aggtcctgga accaccccac ccccacacct ggacgctcgc 3400

 tctggtgggg gcacacgcag gtggaggtgg ttgtgggtgc aggtgtgtgc 3450

 aggggtgtgg ggggcgcagg ggtgtggctt agctggcccc gcacccaggc 3500

 cggggaggct caagttcgcc actttactca gaccgatgca cagtcttccc 3550

 attttacact tttttaataa acataattgc aatattttag gtgggctgcg 3600

 agctgcagtc agccttcacg tctggcctca gtccccgtgt cagtgccgct 3650

 ctgcgtgtgc gtgtgcgcgt gtgtgagcct ctacacatat atatacgtac 3700

 agagccttaa accacatcgt ggcggtgccg tctgagctgt agcgggtggc 3750

 tttgtttcca gtttttgtac ccgtgtcctt gtctcccctc ctcccccatc 3800

 tggggatgtg tctgtgttcc acaccttgaa ataaacagac acatacgtgt 3850

 tctcttaaaa aaaaaaaaaa aaa 3873

<210> 4917
<211> 879
<212> PRT
<213> Homo sapien

<400> 4917
 Met Lys Glu Glu Ala Phe Leu Arg Arg Arg Phe Ser Leu Cys Pro
   1               5                  10                  15

 Pro Ser Ser Thr Pro Gln Lys Val Asp Pro Arg Lys Leu Thr Arg
                  20                  25                  30

 Asn Leu Leu Leu Ser Gly Asp Asn Glu Leu Tyr Pro Leu Ser Pro
                  35                  40                  45

 Gly Lys Asp Met Glu Pro Asn Gly Pro Ser Leu Pro Arg Asp Glu
                  50                  55                  60

 Gly Pro Pro Thr Pro Ser Ser Ala Thr Lys Val Pro Pro Ala Glu
                  65                  70                  75

 Tyr Arg Leu Cys Asn Gly Ser Asp Lys Glu Cys Val Ser Pro Thr
                  80                  85                  90

 Ala Arg Val Thr Lys Lys Glu Thr Leu Lys Ala Gln Lys Glu Asn
                  95                 100                 105

 Tyr Arg Gln Glu Lys Lys Arg Ala Thr Arg Gln Leu Leu Ser Ala
                 110                 115                 120

 Leu Thr Asp Pro Ser Val Val Ile Met Ala Asp Ser Leu Lys Ile
                 125                 130                 135

 Arg Gly Thr Leu Lys Ser Trp Thr Lys Leu Trp Cys Val Leu Lys
                 140                 145                 150

 Pro Gly Val Leu Leu Ile Tyr Lys Thr Pro Lys Val Gly Gln Trp
                 155                 160                 165

 Val Gly Thr Val Leu Leu His Cys Cys Glu Leu Ile Glu Arg Pro
                 170                 175                 180

 Ser Lys Lys Asp Gly Phe Cys Phe Lys Leu Phe His Pro Leu Asp
                 185                 190                 195

 Gln Ser Val Trp Ala Val Lys Gly Pro Lys Gly Glu Ser Val Gly
                 200                 205                 210

 Ser Ile Thr Gln Pro Leu Pro Ser Ser Tyr Leu Ile Phe Arg Ala
                 215                 220                 225

 Ala Ser Glu Ser Asp Gly Arg Cys Trp Leu Asp Ala Leu Glu Leu
                 230                 235                 240

 Ala Leu Arg Cys Ser Ser Leu Leu Arg Leu Gly Thr Cys Lys Pro
                 245                 250                 255

 Gly Arg Asp Gly Glu Pro Gly Thr Ser Pro Asp Ala Ser Pro Ser
                 260                 265                 270

 Ser Leu Cys Gly Leu Pro Ala Ser Ala Thr Val His Pro Asp Gln
                 275                 280                 285

 Asp Leu Phe Pro Leu Asn Gly Ser Ser Leu Glu Asn Asp Ala Phe
                 290                 295                 300

 Ser Asp Lys Ser Glu Arg Glu Asn Pro Glu Glu Ser Asp Thr Glu
                 305                 310                 315

 Thr Gln Asp His Ser Arg Lys Thr Glu Ser Gly Ser Asp Gln Ser
                 320                 325                 330

 Glu Thr Pro Gly Ala Pro Val Arg Arg Gly Thr Thr Tyr Val Glu
                 335                 340                 345

 Gln Val Gln Glu Glu Leu Gly Glu Leu Gly Glu Ala Ser Gln Val
                 350                 355                 360

 Glu Thr Val Ser Glu Glu Asn Lys Ser Leu Met Trp Thr Leu Leu
                 365                 370                 375

 Lys Gln Leu Arg Pro Gly Met Asp Leu Ser Arg Val Val Leu Pro
                 380                 385                 390

 Thr Phe Val Leu Glu Pro Arg Ser Phe Leu Asn Lys Leu Ser Asp
                 395                 400                 405

 Tyr Tyr Tyr His Ala Asp Leu Leu Ser Arg Ala Ala Val Glu Glu
                 410                 415                 420

 Asp Ala Tyr Ser Arg Met Lys Leu Val Leu Arg Trp Tyr Leu Ser
                 425                 430                 435

 Gly Phe Tyr Lys Lys Pro Lys Gly Ile Lys Lys Pro Tyr Asn Pro
                 440                 445                 450

 Ile Leu Gly Glu Thr Phe Arg Cys Cys Trp Phe His Pro Gln Thr
                 455                 460                 465

 Asp Ser Arg Thr Phe Tyr Ile Ala Glu Gln Val Ser His His Pro
                 470                 475                 480

 Pro Val Ser Ala Phe His Val Ser Asn Arg Lys Asp Gly Phe Cys
                 485                 490                 495

 Ile Ser Gly Ser Ile Thr Ala Lys Ser Arg Phe Tyr Gly Asn Ser
                 500                 505                 510

 Leu Ser Ala Leu Leu Asp Gly Lys Ala Thr Leu Thr Phe Leu Asn
                 515                 520                 525

 Arg Ala Glu Asp Tyr Thr Leu Thr Met Pro Tyr Ala His Cys Lys
                 530                 535                 540

 Gly Ile Leu Tyr Gly Thr Met Thr Leu Glu Leu Gly Gly Lys Val
                 545                 550                 555

 Thr Ile Glu Cys Ala Lys Asn Asn Phe Gln Ala Gln Leu Glu Phe
                 560                 565                 570

 Lys Leu Lys Pro Phe Phe Gly Gly Ser Thr Ser Ile Asn Gln Ile
                 575                 580                 585

 Ser Gly Lys Ile Thr Ser Gly Glu Glu Val Leu Ala Ser Leu Ser
                 590                 595                 600

 Gly His Trp Asp Arg Asp Val Phe Ile Lys Glu Glu Gly Ser Gly
                 605                 610                 615

 Ser Ser Ala Leu Phe Trp Thr Pro Ser Gly Glu Val Arg Arg Gln
                 620                 625                 630

 Arg Leu Arg Gln His Thr Val Pro Leu Glu Glu Gln Thr Glu Leu
                 635                 640                 645

 Glu Ser Glu Arg Leu Trp Gln His Val Thr Arg Ala Ile Ser Lys
                 650                 655                 660

 Gly Asp Gln His Arg Ala Thr Gln Glu Lys Phe Ala Leu Glu Glu
                 665                 670                 675

 Ala Gln Arg Gln Arg Ala Arg Glu Arg Gln Glu Ser Leu Met Pro
                 680                 685                 690

 Trp Lys Pro Gln Leu Phe His Leu Asp Pro Ile Thr Gln Glu Trp
                 695                 700                 705

 His Tyr Arg Tyr Glu Asp His Ser Pro Trp Asp Pro Leu Lys Asp
                 710                 715                 720

 Ile Ala Gln Phe Glu Gln Asp Gly Ile Leu Arg Thr Leu Gln Gln
                 725                 730                 735

 Glu Ala Val Ala Arg Gln Thr Thr Phe Leu Gly Ser Pro Gly Pro
                 740                 745                 750

 Arg His Glu Arg Ser Gly Pro Asp Gln Arg Leu Arg Lys Ala Ser
                 755                 760                 765

 Asp Gln Pro Ser Gly His Ser Gln Ala Thr Glu Ser Ser Gly Ser
                 770                 775                 780

 Thr Pro Glu Ser Cys Pro Glu Leu Ser Asp Glu Glu Gln Asp Gly
                 785                 790                 795

 Asp Phe Val Pro Gly Gly Glu Ser Pro Cys Pro Arg Cys Arg Lys
                 800                 805                 810

 Glu Ala Arg Arg Leu Gln Ala Leu His Glu Ala Ile Leu Ser Ile
                 815                 820                 825

 Arg Glu Ala Gln Gln Glu Leu His Arg His Leu Ser Ala Met Leu
                 830                 835                 840

 Ser Ser Thr Ala Arg Ala Ala Gln Ala Pro Thr Pro Gly Leu Leu
                 845                 850                 855

 Gln Ser Pro Arg Ser Trp Phe Leu Leu Cys Val Phe Leu Ala Cys
                 860                 865                 870

 Gln Leu Phe Ile Asn His Ile Leu Lys
                 875

<210> 4918
<211> 799
<212> DNA
<213> Homo sapien

<400> 4918
 aatacaaagc aggcccgtta accaacagtt gaaattaagg gcccttccag 50

 accccccagc tgagaagaag tctgctactg aaaggagctc acaatttaac 100

 aggagagaga gagaaagata cactgtgaag gatagtcaaa agacattgca 150

 aagaggagga ctggtactgt ccccaccccc actaagagct taagatagaa 200

 cagtctgaat gagactctga aatatattta aaatgatgaa agaaaaatgt 250

 cagctttcct ctttccagtc aagacaggtg ggatcccatt gtttaatcta 300

 gaaatacctg tgtgagatac tagtattgat ggtgagacgt caatagtaaa 350

 atatcttgga ggtaaaacta aacattcttc agtcatttaa ataccagcac 400

 agcaggcctg tttgccagtt cactaactac cttgttgcca cagtagttga 450

 ctgccttttt ttcagcaaag ggaataatga tttagagggt agacgagtga 500

 gtcacaatgt aacttggctc agacaagaag aataaagcaa ggattactat 550

 gcagatggaa ttggctgtta ctatgatgac agtaatgtgt taaggggctt 600

 ttccagcaca ggatcctgaa gaaacttaac ccaaatctac atctgttccc 650

 ttttcattga aatctaacct cccattggcc acagagcctc aagcctaata 700

 tttgaggaca gtcagcatgc acgcaagaat gctttacctc ataagtagga 750

 aagagaattt gggtcacaga aaccagggca aattttctgc tcttaaatg 799

<210> 4919
<211> 63
<212> PRT
<213> Homo sapien

<400> 4919
 Ile Gln Ser Arg Pro Val Asn Gln Gln Leu Lys Leu Arg Ala Leu
   1               5                  10                  15

 Pro Asp Pro Pro Ala Glu Lys Lys Ser Ala Thr Glu Arg Ser Ser
                  20                  25                  30

 Gln Phe Asn Arg Arg Glu Arg Glu Arg Tyr Thr Val Lys Asp Ser
                  35                  40                  45

 Gln Lys Thr Leu Gln Arg Gly Gly Leu Val Leu Ser Pro Pro Pro
                  50                  55                  60

 Leu Arg Ala


<210> 4920
<211> 5534
<212> DNA
<213> Homo sapien

<400> 4920
 caggaaaagt tttttacata cgaattaaag atgcttcttt atgcaaattt 50

 ttaaacccca ggtttgaagt aggataaaag gtaacattaa atctgagatc 100

 atttctagct ctggaattct gtgattgtaa tgagttttga tttctaaatg 150

 ttttttcctt tcataatttc agggttagtc agcaacataa aatcaaccta 200

 atgacagcag acaacttatc catctgtttt tggccaacct tgatgagacc 250

 tgattttgaa aatcgagagt ttctgtctac tactaagatt catcaatctg 300

 ttgttgaaac attcattcag cagtgtcagt ttttctttta caatggagaa 350

 attgtagaaa cgacaaacat tgtggctcct ccaccacctt caaacccagg 400

 acagttggtg gaaccaatgg tgccacttca gttgccgcca ccattgcaac 450

 ctcagctgat acaaccacag ttacaaacgg atcctcttgg tattatatga 500

 gtaggaagtg attgcaaaca ggctggattt ggacaaaaag caaatctaga 550

 catgcatgtt tcagggttca gtagtatact tcatgtttca tacagataat 600

 tcacattcaa aattacattt tctctttgaa ctagatggta ttccttattc 650

 acttacatta caaatctaag accatgtgat aagcatgact ggagaggttt 700

 aatttttata aacaaaaata gctataaagt acaaagctgc tgctgcatgc 750

 aaccttattg caatcagtat atcattcctg tggcaatttc tgtcacctta 800

 tattgtgaat aaaatttttc tatagaaatt aaatgattta aaaactcacc 850

 tatatgaaac atttaatgct tttcagcctg ctttctggct gattttgtta 900

 tttgatgtgc taatttgggc aacttaattt acattctggc agtcggtgta 950

 gataactaaa agcccagtta agtattttat aatttcaggc tactgaggcc 1000

 atgcttggga tgttgtttga aagaaagaaa aaatacactt gacatatttc 1050

 acatttctgt accttcatct ttacttccaa gtaaacccgt ggatgatttg 1100

 atgagggata aatgaaccta tttcttttac acacatacca aggacatgct 1150

 tgtggctaaa gtgagttgat aatgttgtgc aaaggatagt tgtcaccaac 1200

 tcatttcttt atggtccata atgaaataaa aattttgtat actgttaatt 1250

 ctgtaaacag atgcatgttc aaaagatcta tgatggtctt gtaatcttaa 1300

 tctaatatat tttagatatt ttaatttttt ccctcttggg gaacacattt 1350

 agtatagtgt agaaaatact tccatgacat tttcatataa ggttatataa 1400

 cttttcatac ataaacatga aatttgttgt agaaaattct ttaaaccaaa 1450

 catttaaatc taggacttca atttaatttg ttccttgaat ctatttttat 1500

 gtggccctta aaaaatatcc aaaaaaccca ttgctaatat agcaataaaa 1550

 atactttggg tactgacaga ctctttggag tgtttatatt acaaatttgt 1600

 attcatattc ttttctgtga tgtgttgtac taaaatccaa aatggctttt 1650

 gcaccatttt taagccaatt ttttcctttg atgttggtac cagaattact 1700

 ataagtgact gctgcttttg ggggtaaaca ttttgttagt gaagataaaa 1750

 ccagaacact aaattatgga taaaattttc agaataggtg gcacaggtaa 1800

 atttcactag gttatatttt gtgtagtaaa gaaaaaaatt atttggtcaa 1850

 tgttatctta attcatacta caatttaaga ttatcttatg tgtattatag 1900

 taaatagatg attttcagat tcaaggctcc taagagtttg atttgctctg 1950

 ttttttccta aaataaatat tgtctctccc aactgttaag ttctaggtat 2000

 tgtacttcca attttaactt cagaaccaag atgttggcat gaaccaggct 2050

 gctgttgaag tacatgtata ttataaatta tcttatttgt gttatactct 2100

 tacatgttat cttttctaag aaaacaaagt ccctattatt cctattgcaa 2150

 agcacacagg aattaagaaa gtacagtaat ttttaaaaaa aaatccggta 2200

 aatgtagtat tcttaacctg ttctatatta cttataccta ttgtctatat 2250

 agctttaatt tatagttgtc agtttaacta ttggcatgtc tggcaaagaa 2300

 aattaaactt taagagtttt ataaactgtt tctaggttgc taaagaattt 2350

 atttttctac tatatatggt atagacaaag catcaaacta tgtacaggaa 2400

 aaaagcctga ctatttctat ttggaagtag gctgaaaaga gaattttcaa 2450

 aactgttcgt gtcttcagtt cattctgtca taactttgct attgtaatat 2500

 gtgaatacca gtttatttaa gctgttctct tttatactgt attaatttaa 2550

 tgttcatctg cgtttagtac catttttgtt attaaaactg gcatttaccg 2600

 tttttcacat taacccacct tgcaccttcc cccaaactta tctccacttt 2650

 tctatgcatt ctatcattga tttgacacac ttcatagtga gtcatttaaa 2700

 tactctacgt ttggttcaat taaccagtag gttacagtta ttgaaaatta 2750

 aagtacagtt taaagctcag tctgttacac tgaattgatt gtgtttgttt 2800

 ttgccaaggg tttagatatg cttttaaata ttagaaacat ctaagaacag 2850

 aataacataa ttaaactttt ttctggtaag ttactggaag gtttcactgt 2900

 ttagggacct atcatatgag acttcttaaa ggattaaaag aataggatag 2950

 tctcataatt gtgagtaaac atcaaggcat tatattttac aatactgaat 3000

 aaaatttcat ctacacacat gttgccattg tttcatttaa ggttcagtgc 3050

 ttatagttaa ctacaatatt ggacctaaca ggatctagat tagcaatata 3100

 aagaagcata gtggtactct gtttcacact ttcagtagat ttattagaag 3150

 tcaaattcta ttcaacagac acttattagg atatacaact aatttaagaa 3200

 taaaattcca ggcacaatat atttttttta aatggtattt gttagtagtg 3250

 cttcttcccc ttaacattta cagtgtaaat actgcaggta accgcaatct 3300

 aagttagcca aaaagcagct ttttttccca tactgtatgt aaataatgta 3350

 gacctgggtt tttttgttta tttgggtttg tttttttttt tgaggtactg 3400

 gaatctaatt aatatctctt aggtatcaac aaaagggaac aattggaatg 3450

 agaatttagg ccttagcttc catggtgatt tttagttttt tatacagtaa 3500

 taattgtgat gctatttgtc aactggatat aaatacacat ataattttaa 3550

 aaagtcaaaa gtgcttttgt ttctttgttt aatgtaattt ttgtgcttca 3600

 cctacaggat gctgcagtaa attaaatatc agtgaagctt ctgatgtata 3650

 aagaatgcta tgaataaaac attaagaagc tgtgtaattt taagttatag 3700

 ttgcctctat ttttaccatt tcattggtaa aaattagcta atttttttca 3750

 agtgaaatga aaaataaaaa tataaattta tcaatatgat ggaaatctta 3800

 ttaaggagat gtattattga attttcactg tacctgaaaa ggagattcaa 3850

 aattttttct ggggatgtat ataggtgaaa atttgatttt ttaaattatc 3900

 aggaaaacaa gataatgcac agatttctaa gactaagatc ttacctggat 3950

 gtgatttttg agctgtggct agacattctt tagagccact ggaaatattt 4000

 tgaaaactat tctagttata gcagagctgc taatattaac gaatatattt 4050

 gtgtcttcat ggtttgtgac tattaggcca aattttgtgg tatatgttgt 4100

 cagtctggat ctggtgaggt ctgttcaaca tgaatctttg tgttatcttg 4150

 aatttagtag tttcaaggta cttaaattct taacagtttc taatttgttt 4200

 caatacatat gggacatggt tgattttttt actgtattag aactcttgga 4250

 agttcttagc cttttcaggt tatgaaatac ctgaaagtaa aattttctaa 4300

 gatttaataa gggaagatac tattcaaatc attttcttag gatagcatct 4350

 ttacatacaa tgagaggatt gtacaagcat taatctcata ttccaacatc 4400

 cagttacttg atgtgatcca agtaccctgg tctttttgaa gcagttaaaa 4450

 tctaattaat taactttggg agtcttcact attcaattga tcctcatcat 4500

 tgtcctattt gcatgactcc attttttcct ccactatatg agttttcttt 4550

 gtcaggggga gaggagtggg aagagtcaca gaatctcata ttcacatctt 4600

 aattaaattg tgtgaaatta gtcttttgtg gaaattctgt aggcagtatg 4650

 attttgaaaa gctaaccaat gataattagc attttagtta atactaaatg 4700

 cataaaatta taacccttga aattaatttg gtgctggcag ttctggttta 4750

 gtcattttta ccagtagtta gtagtattaa gacctgcagt atatgcactt 4800

 tttgagtagc tgtcaaataa ttgtagttga gaaacaactt gtttattctc 4850

 acaattcaga ttttctattc agttttgtct caaatagtaa gttattgtga 4900

 acaatttaat aacggccctc ctgttctagt ttgcctaata ttttagttaa 4950

 gatttagtgt tttaacctat ttttttaagt ttattttttg tattagattt 5000

 tatttgaata agttatgtgg gtttagtaat tgacctattt attcattgct 5050

 tcactaattc atccagatta gttttaagtg tgtatatgta tttgctcacc 5100

 agatcatttt cttgggacct tgaactgtga atgttttgtc ctaaccattt 5150

 aatattttct aggtacttgc tgcaagttct tgaactattt taccagcttt 5200

 aactttgggg ctcttagttt cttttctcca gattcttgtt attttatttt 5250

 atccaaataa atatttaggt gttctaagaa gtagacttct gtctaattcc 5300

 gtaaaatagg taaaatcaga agctgtacac actatcatac tgttattatt 5350

 tgggattgtt tataaatgta ggtgaaagga taaaaaatac ctatctgaga 5400

 gaatacagcc tttagatatc cttcttggaa atttgactta gagatttttc 5450

 atttgttggc agtcacaggc atagctgctg aatgtctttt ggtctgtaat 5500

 atttgaagtg agaaacatta ccagcaatgt actt 5534

<210> 4921
<211> 99
<212> PRT
<213> Homo sapien

<400> 4921
 Met Thr Ala Asp Asn Leu Ser Ile Cys Phe Trp Pro Thr Leu Met
   1               5                  10                  15

 Arg Pro Asp Phe Glu Asn Arg Glu Phe Leu Ser Thr Thr Lys Ile
                  20                  25                  30

 His Gln Ser Val Val Glu Thr Phe Ile Gln Gln Cys Gln Phe Phe
                  35                  40                  45

 Phe Tyr Asn Gly Glu Ile Val Glu Thr Thr Asn Ile Val Ala Pro
                  50                  55                  60

 Pro Pro Pro Ser Asn Pro Gly Gln Leu Val Glu Pro Met Val Pro
                  65                  70                  75

 Leu Gln Leu Pro Pro Pro Leu Gln Pro Gln Leu Ile Gln Pro Gln
                  80                  85                  90

 Leu Gln Thr Asp Pro Leu Gly Ile Ile
                  95

<210> 4922
<211> 2742
<212> DNA
<213> Homo sapien

<400> 4922
 aggttactat agtgtctgct cctacccctg ggacaagatc ccctaatgag 50

 ctggcaggtg ggcgtggggg gcacaggtac agcttggctt ctcagctttg 100

 ctcccctatc ctctgctttg ccatgaatct ctcatccagc cccgcaggga 150

 tctgcctggc cagcagtgag cctgagcccc tttcatcctg ggacctgccg 200

 accacggctc acatcctcct gggtgaagaa tgtcaccttg cttcctatct 250

 gcctctttcg tggttggctg gggaggggga ccggggggtg gggtgaggtt 300

 aacctcattg ttgtcttata tggtcattta aatctcccag ggcttcctcc 350

 aagggccaaa aataatccgg agacacagca gctgtgtcca gcacacagag 400

 gacccggcca tctgctttgg ttcagagccc tgtgtctgtc agtcagtctc 450

 tccctggctc tccctccatc ctcattcctg cctgaagcca tgacccgctt 500

 ctcctatgca gagtactttt ccctctttca ctcctgctct gcaccctcca 550

 ggtccactgc acctcctgag agttcgccgg cccgggcccc aatgggcttg 600

 ttccaagggg tcatgcagaa atacagcagc agcttgttca agacctccca 650

 gctggcgcct gcggacccct tgataaaggc catcaaggat ggcgatgaag 700

 aggccttgaa gaccatgatc aaggaaggga agaatctcgc agagcccaac 750

 aaggagggct ggctgccgct gcacgaggcc gcatactatg gccaggtggg 800

 ctgcctgaaa gtcctgcagc gagcgtaccc agggaccatc gaccagcgca 850

 ccctgcagga ggaaacagcc gtttacttgg caacgtgcag gggccacctg 900

 gactgtctcc tgtcactgct ccaagcaggg gcagagccgg acatctccaa 950

 caaatcccga gagacaccgc tctacaaagc ctgcgagcgc aagaacgcgg 1000

 aggccgtgaa gattctggtg cagcacaacg cagacaccaa ccaccgctgc 1050

 aaccgcggct ggaccgctct gcacgagtct gtgtctcgca atgacctgga 1100

 ggtcatgcag atcctggtga gcggaggagc caaggtggaa tccaagaacg 1150

 cctacggcat cacccccttg ttcgtggccg cccagagtgg acagttggag 1200

 gccttgaggt tcttagccaa gtacggtgct gacatcaaca cgcaggccag 1250

 cgacaacgcg tctgccctct acgaggcctg caagaatgag catgaggagg 1300

 tggtggagtt tctgctgtca cagggtgccg acgccaacaa gaccaacaag 1350

 gacggcttgc tcccgctgca catcgcctcc aagaagggca actacaggat 1400

 cgtgcagatg ctgctgccgg tgaccagccg cacgcgcata cgccgtagcg 1450

 gcgtcagtcc gctgcacctg gcggccgagc gcaaccacga cgaggtgctg 1500

 gaggcgctgc tgagcgcgcg cttcgacgtg aacacgccgc tggcgcccga 1550

 gcgcgcgcgc ctctacgaag accggcgcag ctccgcgctg tacttcgcgg 1600

 tggtcaacaa caacgtgtac gccaccgagc tgctgctgca acacggcgcc 1650

 gaccccaacc gcgacgtcat cagccccttg ctcgtggcca tccgccacgg 1700

 ctgcctgcgc acaatgcagc tgctgctgga ccacggcgcg aacatcgacg 1750

 cctatatcgc cacgcacccc accgccttcc ccgccaccat catgttcgcc 1800

 atgaagtgcc tgtcgctgct caagttcctc atggacctgg gctgcgacgg 1850

 cgagccctgc ttctcatgcc tctacggcaa cggcccgcac ccgccggccc 1900

 cgcagccctc cagcaggttc aacgacgcgc ccgcggccga caaggagccc 1950

 agcgtggtgc agttctgtga gttcgtatct gccccagagg tgagccgctg 2000

 ggcggggccc atcatcgatg tcctcctgga ctacgtgggc aacgtgcagc 2050

 tctgctcgcg gctgaaggaa cacatcgaca gctttgagga ctgggccgtc 2100

 atcaaggaga aggcagaacc tccaagacct ctggctcacc tttgccgact 2150

 gcgggttcga aaggccattg ggaaataccg tataaaactc ctagacacct 2200

 tgccgctccc aggcaggctg attagatacc tgaaatacga gaacacccag 2250

 taactggggc cacggggaga gaggagtagc ccctcagact cttcttacta 2300

 agtctcagga cgtcggtgtt cccaactcca aggggacctg gtgacagacg 2350

 aggctgcagg ctgcctccct ctcagcctgg acagctacca ggatctcact 2400

 gggtctcagg gcccagagct ttggccagag cagagaacag aatgtgtcaa 2450

 ggagaagaat catttgttta caaactgatg agcagatccc agaccttctc 2500

 taccttcagg aatggcagaa acctctattc ctggggccag ggcagagctt 2550

 gaggtgttct ggggaaggtg gtgctcagag ccttccctgt gcccctccac 2600

 ttgttctgga aaactcacca cttgacttca gagctttctc tccaaagact 2650

 aagatgaaga cgtggcccaa ggtagggggt agggggagcc tgggtcttgg 2700

 agggctttgt taagtattaa tataataaat gttacacatg tg 2742

<210> 4923
<211> 587
<212> PRT
<213> Homo sapien

<400> 4923
 Met Thr Arg Phe Ser Tyr Ala Glu Tyr Phe Ser Leu Phe His Ser
   1               5                  10                  15

 Cys Ser Ala Pro Ser Arg Ser Thr Ala Pro Pro Glu Ser Ser Pro
                  20                  25                  30

 Ala Arg Ala Pro Met Gly Leu Phe Gln Gly Val Met Gln Lys Tyr
                  35                  40                  45

 Ser Ser Ser Leu Phe Lys Thr Ser Gln Leu Ala Pro Ala Asp Pro
                  50                  55                  60

 Leu Ile Lys Ala Ile Lys Asp Gly Asp Glu Glu Ala Leu Lys Thr
                  65                  70                  75

 Met Ile Lys Glu Gly Lys Asn Leu Ala Glu Pro Asn Lys Glu Gly
                  80                  85                  90

 Trp Leu Pro Leu His Glu Ala Ala Tyr Tyr Gly Gln Val Gly Cys
                  95                 100                 105

 Leu Lys Val Leu Gln Arg Ala Tyr Pro Gly Thr Ile Asp Gln Arg
                 110                 115                 120

 Thr Leu Gln Glu Glu Thr Ala Val Tyr Leu Ala Thr Cys Arg Gly
                 125                 130                 135

 His Leu Asp Cys Leu Leu Ser Leu Leu Gln Ala Gly Ala Glu Pro
                 140                 145                 150

 Asp Ile Ser Asn Lys Ser Arg Glu Thr Pro Leu Tyr Lys Ala Cys
                 155                 160                 165

 Glu Arg Lys Asn Ala Glu Ala Val Lys Ile Leu Val Gln His Asn
                 170                 175                 180

 Ala Asp Thr Asn His Arg Cys Asn Arg Gly Trp Thr Ala Leu His
                 185                 190                 195

 Glu Ser Val Ser Arg Asn Asp Leu Glu Val Met Gln Ile Leu Val
                 200                 205                 210

 Ser Gly Gly Ala Lys Val Glu Ser Lys Asn Ala Tyr Gly Ile Thr
                 215                 220                 225

 Pro Leu Phe Val Ala Ala Gln Ser Gly Gln Leu Glu Ala Leu Arg
                 230                 235                 240

 Phe Leu Ala Lys Tyr Gly Ala Asp Ile Asn Thr Gln Ala Ser Asp
                 245                 250                 255

 Asn Ala Ser Ala Leu Tyr Glu Ala Cys Lys Asn Glu His Glu Glu
                 260                 265                 270

 Val Val Glu Phe Leu Leu Ser Gln Gly Ala Asp Ala Asn Lys Thr
                 275                 280                 285

 Asn Lys Asp Gly Leu Leu Pro Leu His Ile Ala Ser Lys Lys Gly
                 290                 295                 300

 Asn Tyr Arg Ile Val Gln Met Leu Leu Pro Val Thr Ser Arg Thr
                 305                 310                 315

 Arg Ile Arg Arg Ser Gly Val Ser Pro Leu His Leu Ala Ala Glu
                 320                 325                 330

 Arg Asn His Asp Glu Val Leu Glu Ala Leu Leu Ser Ala Arg Phe
                 335                 340                 345

 Asp Val Asn Thr Pro Leu Ala Pro Glu Arg Ala Arg Leu Tyr Glu
                 350                 355                 360

 Asp Arg Arg Ser Ser Ala Leu Tyr Phe Ala Val Val Asn Asn Asn
                 365                 370                 375

 Val Tyr Ala Thr Glu Leu Leu Leu Gln His Gly Ala Asp Pro Asn
                 380                 385                 390

 Arg Asp Val Ile Ser Pro Leu Leu Val Ala Ile Arg His Gly Cys
                 395                 400                 405

 Leu Arg Thr Met Gln Leu Leu Leu Asp His Gly Ala Asn Ile Asp
                 410                 415                 420

 Ala Tyr Ile Ala Thr His Pro Thr Ala Phe Pro Ala Thr Ile Met
                 425                 430                 435

 Phe Ala Met Lys Cys Leu Ser Leu Leu Lys Phe Leu Met Asp Leu
                 440                 445                 450

 Gly Cys Asp Gly Glu Pro Cys Phe Ser Cys Leu Tyr Gly Asn Gly
                 455                 460                 465

 Pro His Pro Pro Ala Pro Gln Pro Ser Ser Arg Phe Asn Asp Ala
                 470                 475                 480

 Pro Ala Ala Asp Lys Glu Pro Ser Val Val Gln Phe Cys Glu Phe
                 485                 490                 495

 Val Ser Ala Pro Glu Val Ser Arg Trp Ala Gly Pro Ile Ile Asp
                 500                 505                 510

 Val Leu Leu Asp Tyr Val Gly Asn Val Gln Leu Cys Ser Arg Leu
                 515                 520                 525

 Lys Glu His Ile Asp Ser Phe Glu Asp Trp Ala Val Ile Lys Glu
                 530                 535                 540

 Lys Ala Glu Pro Pro Arg Pro Leu Ala His Leu Cys Arg Leu Arg
                 545                 550                 555

 Val Arg Lys Ala Ile Gly Lys Tyr Arg Ile Lys Leu Leu Asp Thr
                 560                 565                 570

 Leu Pro Leu Pro Gly Arg Leu Ile Arg Tyr Leu Lys Tyr Glu Asn
                 575                 580                 585

 Thr Gln


<210> 4924
<211> 4628
<212> DNA
<213> Homo sapien

<400> 4924
 cattttctag cacactgcac tgtcgtgtag acttgtggga agaacttttc 50

 ccgttttcaa gctccacgct gcatcacagg aaatgacact gaccagatta 100

 agctacaaat acaagtctcg cagccagtct caaagtctgt aaccccaata 150

 acatttttta ggtaaataaa aattgttact gggtggtctt cccttctcca 200

 ggaagcagag ctgaggctgg taaagttcct gcctgagatt ttggccttgc 250

 aaagggatct agtgaagcag ttccagaacg tccagcaagt tgaatacagc 300

 tccatcagag gcttcctcag caagcacagc tcagatgggt tgaggcagct 350

 gcttcacaac aggatcacag tctttctgtc cacatggaac aaactgagga 400

 gatcgcttga gacgaacggt gagatcaacc tacccaaaga ctactgcagc 450

 actgacttgg atctggacac tgagtttgag atcctcttgc cacgccgacg 500

 gggcctgggc ctctgtgcta ccgctctcgt cagctacttg attcgcctac 550

 acaatgaaat tgtctacgcc gtggaaaaac tctccaagga aaacaacagc 600

 tattccgtgg atgccgccga ggtcactgaa ctgcatgtca tcagttatga 650

 agtggagcgg gacctgactc cactgattct ctccaactgc cagtaccagg 700

 tggaggaggg cagagagacc gtgcaggagt tcgatctgga gaagattcag 750

 cggcagatcg tcagccgctt cctccagggc aagccccggc tgagcctcaa 800

 gggaataccc actctggtgt acagacacga ctggaactat gaacatctct 850

 ttatggacat caagaacaaa atggcacagg tgatcccgat aaacctgatc 900

 ctgtgcacgg ggctttctgc cttctcagtg tgtttccctc cgtgttaggc 950

 ctactccagc cttgccccgg gtgtttgctg tgagcccaca gtttctgcgg 1000

 cctcccttac agagagcaag caagacagca aatcagcaag ttttcttgta 1050

 gagtaaaagc agattgacat cttgtgggtt tgattcttag gaatgatgtt 1100

 gatgcatggc catgcctgct gaagcgggaa gtccatggaa ccgatttgtt 1150

 cctgctctcc gcatgcgggt actgataggt agacctgtgt gtctccatgg 1200

 cctccaggaa ctgcctgcac accgtgcgcc caagtgtcag ctgttagaga 1250

 gttggccccc cgcatgtggc ttgggcagtg aaggggctcg gctctcttac 1300

 caggtggtga gatgccagaa acccagccca cagacatccc tctcctgctt 1350

 ttcatttccc aggactccct ccccagctcg gtcattagtg ccatcagtgg 1400

 acagctgcag tcctacagcg atgcctgtga agtgctgtct gtcgtagaag 1450

 tcactctggg gtttctgagc acagctggtg gggatccaaa catgcagctg 1500

 aatgtgtata ctcaagacat cctgcaaatg ggtgatcaga cgattcacgt 1550

 gttaaaggcc ttaaacagat gccagttaaa acacaccatt gccctctggc 1600

 agttcctgtc tgctcataag tctgaacagc tgctgcggct gcacaaagag 1650

 ccatttgggg aaatcagttc aaggtacaaa gcggatctga gcccggaaaa 1700

 tgctaagctc ctcagcacat tcctaaatca gactggccta gacgccttcc 1750

 tgctagagct gcacgaaatg ataatcttga aactaaagaa cccccaaacc 1800

 caaaccgagg agcgcttccg ccctcagtgg agcctgagag acactctcgt 1850

 aagttacatg caaactaaag aaagtgaaat tcttcctgaa atggcatctc 1900

 agttcccaga agagatactg ctcgccagct gtgtctcagt gtggaaaaca 1950

 gctgctgtgc tgaaatggaa tcgagaaatg agatagaatt atttcctcag 2000

 ctatctttgg atgactttgg agagaagact cctctctcct cgtctgcggc 2050

 gtggacttga tcatggactg gtgcctttgc attcagaagg agagctgtca 2100

 gcgtagcacc gaattcaaga ccaaggcgtg ctacctgagc tgacagcttt 2150

 ttgaaagccg agctgtttct gaaccatgta catacatgtt ctgaaacttt 2200

 ctcatcattt tatgagtact gttcattgag agatgacaat gaagattaga 2250

 tgaaattgga aataaaccaa cattgtttac attccaggag acttgtagct 2300

 cagccacaca cgcagtaatg acctgtgccc gttcgcctct ggcactgccc 2350

 acccctcttt ttttttttct tctaattctg tactcacaaa agagaatctc 2400

 attttcttct ttcttccatt cccttaaatt ctgagtactg tacatatatt 2450

 tctgggttcc cacgatgatg tgaaaaacta ccagactgtt ttttgtcttc 2500

 tcacaaagac aagaaaaatc agggcatttt gtgagtgcct taagatcaaa 2550

 ctaacaagat ctgaccctct cccctcacag tgagccactg ccccacttca 2600

 gagggtaaga gccaaaagcc tcattgtgaa aggcactgga cttggaccag 2650

 ggacaccatc agggccttgg ttttctcacg cataaaatgg agagtggatt 2700

 aatcgccaaa gattcttctg atctgacatt ttgaaattgt gagagaaact 2750

 agatgactgt aaacttggtc acaggcctgg ttctggcagt tctttgcgga 2800

 cttttttcta gcattatgcc aaataaacat gcagtctcag tgtgctctcg 2850

 catgtatgaa tatctagtcc tttctgtggt tctcagccaa gacataaaaa 2900

 ctaggactca gagcacatac aaaaccagtt atgtttcgga aagagggaaa 2950

 agagtccccg agcccggatc ttgtgctgct tttctcactg acgtgttgcc 3000

 ttttttcttt acaaaatctg ctttgatact taggacctct ctggactaat 3050

 ttctcttcct agacagctca gcacagctat tgatatgtta gaggcagtat 3100

 ccttaatatt cattctaaat gagttaacga cttaacttga aattgggcct 3150

 aaggagtgag aactacaaaa atacaaaatg cttgtccagg actcagccat 3200

 gcacaccttg agcagcgccg gcaggaggca cggaaggaac tgtgctccgt 3250

 tctcctcact gtcatggtgc caccagtgtc tgatgaaggg cagagtgacc 3300

 cagactgcag gcagtaactg acttcacaca gtccctggca tttagtcatc 3350

 tgtgattgtt ttatcactct ggactgtgca gagccacctg ccaccgagat 3400

 ctgcattccg actgcctatg aacgggtgtg ggggccgggg gctggcttgc 3450

 tgaagtcttc aacttgcact cggagctcct ttgatacctc agagctggct 3500

 gtcaggtggc agctcacacc cagactcact ggccacacct cagcaggggg 3550

 ggagtcgagt gtcagtctct ttctgtgaag gctttttttt tcctttggcc 3600

 tgggaatttt tcccattttt atgaaggggt tttaaattgt ttcattttgt 3650

 gtgctgtgct tcaaagcctt aactgtcaaa tcttgcatta tcttgtttgt 3700

 acagaaatat actggcctag cagaggcaaa aaaaaaaaaa tgaattttat 3750

 tttacttgtc acacctgtct taataaactg gagttttgct gctaaagaac 3800

 tcttctctct gggggcagag cttctattta tggcacatag acatcagcta 3850

 ggcttttggg aatcgtttgt gttctttgtg gaaatgtcct ttagaagcac 3900

 ccatgaagta gtgtgttcag actgtgcaca cagaaaacag gctctgcctt 3950

 cacatgtgag acggtggact tttcctctgg acaaaatgac agcatcctgg 4000

 cgactccaca gtggagctga gcgccactcc ctgtagccga tctgggactg 4050

 aaacgcttac acctctgcct cagaaggagt cccccatgcc ctgcctgaaa 4100

 tgacttcact ggacacagcg gggctgcagc taacggggta caggtaggag 4150

 ctaactaact tcacccctga gtccacttgc ggggtaagag ataaacagta 4200

 acccttccag gagcccactg acgttggagt gctaaaaatg ccccttcagg 4250

 gggaaaactg cattttctct tccaaaaagg aaaggttctt ccaggcgaga 4300

 aacctgtggt ctagaaccac agcaagaaga ggaggcatgc tggcctgcac 4350

 cggaagactc actttgtctg ccctgcgcca gcctcacctc accctgcagt 4400

 tcccgtttcc gccatggatg cctcatcacc aaccctgacc ttccccctcc 4450

 caacccttta ttcatcctca ctcccactca tacccgcctc cctggacagt 4500

 tccctgctgc agagttcttt ctgctttcag ccctaccttg gtggtgattt 4550

 acctgaaaat cttcacaact gatcattatc tccttctctt tgagacctga 4600

 ctgaaaaaat taggtgtgca cacctgta 4628

<210> 4925
<211> 224
<212> PRT
<213> Homo sapien

<400> 4925
 Met Pro Glu Thr Gln Pro Thr Asp Ile Pro Leu Leu Leu Phe Ile
   1               5                  10                  15

 Ser Gln Asp Ser Leu Pro Ser Ser Val Ile Ser Ala Ile Ser Gly
                  20                  25                  30

 Gln Leu Gln Ser Tyr Ser Asp Ala Cys Glu Val Leu Ser Val Val
                  35                  40                  45

 Glu Val Thr Leu Gly Phe Leu Ser Thr Ala Gly Gly Asp Pro Asn
                  50                  55                  60

 Met Gln Leu Asn Val Tyr Thr Gln Asp Ile Leu Gln Met Gly Asp
                  65                  70                  75

 Gln Thr Ile His Val Leu Lys Ala Leu Asn Arg Cys Gln Leu Lys
                  80                  85                  90

 His Thr Ile Ala Leu Trp Gln Phe Leu Ser Ala His Lys Ser Glu
                  95                 100                 105

 Gln Leu Leu Arg Leu His Lys Glu Pro Phe Gly Glu Ile Ser Ser
                 110                 115                 120

 Arg Tyr Lys Ala Asp Leu Ser Pro Glu Asn Ala Lys Leu Leu Ser
                 125                 130                 135

 Thr Phe Leu Asn Gln Thr Gly Leu Asp Ala Phe Leu Leu Glu Leu
                 140                 145                 150

 His Glu Met Ile Ile Leu Lys Leu Lys Asn Pro Gln Thr Gln Thr
                 155                 160                 165

 Glu Glu Arg Phe Arg Pro Gln Trp Ser Leu Arg Asp Thr Leu Val
                 170                 175                 180

 Ser Tyr Met Gln Thr Lys Glu Ser Glu Ile Leu Pro Glu Met Ala
                 185                 190                 195

 Ser Gln Phe Pro Glu Glu Ile Leu Leu Ala Ser Cys Val Ser Val
                 200                 205                 210

 Trp Lys Thr Ala Ala Val Leu Lys Trp Asn Arg Glu Met Arg
                 215                 220

<210> 4926
<211> 2311
<212> DNA
<213> Homo sapien

<400> 4926
 cgtgggggcg gtgccggtcg gagggctcct agtgcgccag gttgtgggaa 50

 gtgaggctgg cggtggcgac aaccgaggag gaggggcggg acgccgtgga 100

 gcacggcgac cggctgagcg tcatggaggg ctcaggggag cagccgggcc 150

 cacaaccaca gcatcccgga gaccaccgca tccgcgacgg cgacttcgtg 200

 gtgctgaaac gtgaagatgt gtttaaagca gtacaagtcc agcggagaaa 250

 aaaagtaact ttcgaaaaac agtggttcta cctggataac gtcattggcc 300

 atagttatgg aactgcattt gaagtgacca gtggaggaag tctacagccc 350

 aagaagaaga gggaagagcc tactgcagag actaaagaag cgggcactga 400

 taatcgaaat atagttgatg atgggaaatc tcagaaactt actcaagatg 450

 acataaaagc tttgaaggac aagggcatta aaggagagga aatagttcag 500

 cagttaattg aaaatagtac aacattccga gacaagacag aatttgccca 550

 agataaatat attaaaaaga agaaaaaaaa atatgaagcc atcattactg 600

 ttgtgaagcc atccacccgt attctttcaa ttatgtatta tgcaagagaa 650

 cctggaaaaa ttaaccacat gagatacgat acactagccc agatgttgac 700

 gttgggaaat atccgtgctg gcaacaaaat gattgtgatg gaaacgtgtg 750

 caggcttggt gctgggtgca atgatggaac gaatgggagg ttttggctcc 800

 attattcagc tataccctgg aggaggacct gttcgggcag caacagcatg 850

 ttttggattt cccaaatctt ttctcagtgg tctttatgaa ttccctctca 900

 acaaagtgga cagtcttcta catggaacat tttctgccaa gatgttatct 950

 tcagagccaa aagacagtgc tttggttgaa gaaagtaatg gcacactgga 1000

 ggaaaaacag gcttctgaac aagagaatga agacagcatg gcagaggccc 1050

 cagagagcaa ccacccagaa gaccaggaaa caatggaaac aatttctcaa 1100

 gatccagaac ataaggggcc taaagagaga ggaagcaaaa aagattatat 1150

 tcaggaaaaa cagaggagac aagaagagca gaggaaaaga catttagagg 1200

 ctgccgctct gctgagtgaa agaaacgcag atggtttaat tgtagctagt 1250

 cgtttccacc ccactcccct gctgctgtct ttgctggact ttgtggcccc 1300

 ttcaaggccg tttgtggtct actgtcagta caaagagcct ctgttggaat 1350

 gctacacaaa actgcgggag aggggagggg tcatcaacct caggctgtct 1400

 gaaacctggc tcagaaatta tcaggttttg ccagatcgaa gtcatcctaa 1450

 actgctgatg agtggaggtg ggggttatct tctctccggc ttcaccgttg 1500

 ccatggacaa ccttaaagca gacaccagcc tcaaatctaa tgcaagcact 1550

 ttagaatcac acgagactga ggagcctgca gctaaaaaac gaaaatgccc 1600

 agagtctgac tcttaaccct tttgagaatt gctctgaatt ttgttctcag 1650

 gcattataca gttagtaatt aaactttaaa tgccattact acttgttttt 1700

 tcatatccca agaataagaa catgtctatg tacccgtttc taggaaggag 1750

 gagtatatgc cttttgtcta tttctgacac agatgcattt ggtctgtcaa 1800

 aactgcaacc atggggtatg tagtatgacc aactgcattt aacaaaactc 1850

 ctctaagtac ttctaaatat tctgtgcaaa tatcttgaga acttcaacat 1900

 cctaaaaatg tgtttctaca agactttata ttttaagcta agtggaataa 1950

 tacaacgtaa ctaaaacatg gcgggtaccg aaaggagggc aattcatgga 2000

 agaaatttcc tctgttcatt ccgttctctt caacctaagc aatatggatg 2050

 tgtgagtgtg tgatttatta tggtaccaaa aatgtccacc ttctttcctg 2100

 cagcggaata agcttttttg aaatgctgag gttttatttt aatagttgac 2150

 aacctgggaa agttctgagt atttatttta ctgctctttt ttgtgcatag 2200

 aaaggtttag tagggtactt ttttgcatta atttgccaat actcttattc 2250

 tttgttctaa ataaagtgac tagaattttt gtgtactatt caattaaagg 2300

 aaacaaatgt c 2311

<210> 4927
<211> 497
<212> PRT
<213> Homo sapien

<400> 4927
 Met Glu Gly Ser Gly Glu Gln Pro Gly Pro Gln Pro Gln His Pro
   1               5                  10                  15

 Gly Asp His Arg Ile Arg Asp Gly Asp Phe Val Val Leu Lys Arg
                  20                  25                  30

 Glu Asp Val Phe Lys Ala Val Gln Val Gln Arg Arg Lys Lys Val
                  35                  40                  45

 Thr Phe Glu Lys Gln Trp Phe Tyr Leu Asp Asn Val Ile Gly His
                  50                  55                  60

 Ser Tyr Gly Thr Ala Phe Glu Val Thr Ser Gly Gly Ser Leu Gln
                  65                  70                  75

 Pro Lys Lys Lys Arg Glu Glu Pro Thr Ala Glu Thr Lys Glu Ala
                  80                  85                  90

 Gly Thr Asp Asn Arg Asn Ile Val Asp Asp Gly Lys Ser Gln Lys
                  95                 100                 105

 Leu Thr Gln Asp Asp Ile Lys Ala Leu Lys Asp Lys Gly Ile Lys
                 110                 115                 120

 Gly Glu Glu Ile Val Gln Gln Leu Ile Glu Asn Ser Thr Thr Phe
                 125                 130                 135

 Arg Asp Lys Thr Glu Phe Ala Gln Asp Lys Tyr Ile Lys Lys Lys
                 140                 145                 150

 Lys Lys Lys Tyr Glu Ala Ile Ile Thr Val Val Lys Pro Ser Thr
                 155                 160                 165

 Arg Ile Leu Ser Ile Met Tyr Tyr Ala Arg Glu Pro Gly Lys Ile
                 170                 175                 180

 Asn His Met Arg Tyr Asp Thr Leu Ala Gln Met Leu Thr Leu Gly
                 185                 190                 195

 Asn Ile Arg Ala Gly Asn Lys Met Ile Val Met Glu Thr Cys Ala
                 200                 205                 210

 Gly Leu Val Leu Gly Ala Met Met Glu Arg Met Gly Gly Phe Gly
                 215                 220                 225

 Ser Ile Ile Gln Leu Tyr Pro Gly Gly Gly Pro Val Arg Ala Ala
                 230                 235                 240

 Thr Ala Cys Phe Gly Phe Pro Lys Ser Phe Leu Ser Gly Leu Tyr
                 245                 250                 255

 Glu Phe Pro Leu Asn Lys Val Asp Ser Leu Leu His Gly Thr Phe
                 260                 265                 270

 Ser Ala Lys Met Leu Ser Ser Glu Pro Lys Asp Ser Ala Leu Val
                 275                 280                 285

 Glu Glu Ser Asn Gly Thr Leu Glu Glu Lys Gln Ala Ser Glu Gln
                 290                 295                 300

 Glu Asn Glu Asp Ser Met Ala Glu Ala Pro Glu Ser Asn His Pro
                 305                 310                 315

 Glu Asp Gln Glu Thr Met Glu Thr Ile Ser Gln Asp Pro Glu His
                 320                 325                 330

 Lys Gly Pro Lys Glu Arg Gly Ser Lys Lys Asp Tyr Ile Gln Glu
                 335                 340                 345

 Lys Gln Arg Arg Gln Glu Glu Gln Arg Lys Arg His Leu Glu Ala
                 350                 355                 360

 Ala Ala Leu Leu Ser Glu Arg Asn Ala Asp Gly Leu Ile Val Ala
                 365                 370                 375

 Ser Arg Phe His Pro Thr Pro Leu Leu Leu Ser Leu Leu Asp Phe
                 380                 385                 390

 Val Ala Pro Ser Arg Pro Phe Val Val Tyr Cys Gln Tyr Lys Glu
                 395                 400                 405

 Pro Leu Leu Glu Cys Tyr Thr Lys Leu Arg Glu Arg Gly Gly Val
                 410                 415                 420

 Ile Asn Leu Arg Leu Ser Glu Thr Trp Leu Arg Asn Tyr Gln Val
                 425                 430                 435

 Leu Pro Asp Arg Ser His Pro Lys Leu Leu Met Ser Gly Gly Gly
                 440                 445                 450

 Gly Tyr Leu Leu Ser Gly Phe Thr Val Ala Met Asp Asn Leu Lys
                 455                 460                 465

 Ala Asp Thr Ser Leu Lys Ser Asn Ala Ser Thr Leu Glu Ser His
                 470                 475                 480

 Glu Thr Glu Glu Pro Ala Ala Lys Lys Arg Lys Cys Pro Glu Ser
                 485                 490                 495

 Asp Ser


<210> 4928
<211> 330
<212> DNA
<213> Homo sapien

<400> 4928
 atgatatcct tgagagtttt actggtgatc ctgtggcttc agttaagctg 50

 ggtttggagc caacggaagg aggtggagca ggatcctgga cccttcaatg 100

 ttccagaggg agccactgtc gctttcaact gtacttacag caacagtgct 150

 tctcagtctt tcttctggta cagacaggat tgcaggaaag aacctaagtt 200

 gctgatgtcc gtatactcca gtggtaatga agatggaagg tttacagcac 250

 agctcaatag agccagccag tatatttccc tgctcatcag agactccaag 300

 ctcagtgatt cagccaccta cctctgtgtg 330

<210> 4929
<211> 109
<212> PRT
<213> Homo sapien

<400> 4929
 Met Ile Ser Leu Arg Val Leu Leu Val Ile Leu Trp Leu Gln Leu
   1               5                  10                  15

 Ser Trp Val Trp Ser Gln Arg Lys Glu Val Glu Gln Asp Pro Gly
                  20                  25                  30

 Pro Phe Asn Val Pro Glu Gly Ala Thr Val Ala Phe Asn Cys Thr
                  35                  40                  45

 Tyr Ser Asn Ser Ala Ser Gln Ser Phe Phe Trp Tyr Arg Gln Asp
                  50                  55                  60

 Cys Arg Lys Glu Pro Lys Leu Leu Met Ser Val Tyr Ser Ser Gly
                  65                  70                  75

 Asn Glu Asp Gly Arg Phe Thr Ala Gln Leu Asn Arg Ala Ser Gln
                  80                  85                  90

 Tyr Ile Ser Leu Leu Ile Arg Asp Ser Lys Leu Ser Asp Ser Ala
                  95                 100                 105

 Thr Tyr Leu Cys


<210> 4930
<211> 1335
<212> DNA
<213> Homo sapien

<400> 4930
 cctgtgaggc tcagtaagcc gcagcctaga ttggaacagc gtgactgcct 50

 ggtaggataa aggagacgac atctgaaaag agggtttcag gtgtttgcaa 100

 agaggtcaga tccctacaca tgaaacgctg cggccacagc tgcagccatg 150

 ctacctgcca catgccctgg cctgcgtcag cgttatggag taggcaacct 200

 ggttcggcgc aaagaggaaa tgcgcgttct gtgcccagtc ctcgctcccc 250

 tttgccaacc gggctgctga gtgtgatgct ccctttgtga agtggacatc 300

 tgtctaatgg gaactggacg gtgaccacca gtccgtttta cacaggccac 350

 catacagctg ccaggtggcg ctggctctta gctgttctgc aagtccagca 400

 cagggtgtat tcagctctag aggtggcaaa cacggggccc ttccaccagg 450

 cccactccct gcaaaggaag tgcttccgag agccaaggct ttgctctaat 500

 ctctgtgaag gaagaaaaag acttggggaa aggtaatgaa taaattaaag 550

 acacactttt gtaatcgtat attttaggct ttcctctcta cctaattgtg 600

 ctctaatctg tacttaggag tatagttttt taagtgggac atgtcaggct 650

 tttatgccac agattaaact ccaaggcaaa taaatgtgtg acagcttaag 700

 aggcgaaaag aagagtcttc gtcaaatggc agagtttgat tgtttaacct 750

 agactaatca gtctttggag ggcctgccac atgtcttcca gacggctaga 800

 atgctcagga gataagagtg gggcctatcg ctctgtggct ttctccccct 850

 gcattagccg cagagctgag tgagtctatg aaaacccatt ggtcgggctg 900

 ccctagcaac acagaatgct gtgctgacac atactccatc acatgtttgc 950

 gatgaaaatg ctgtattttt agaacacttc aaagtcagga aaccgttaaa 1000

 ccacactgca tcctctcttg ccctctggcc acttcctcca cacccccagg 1050

 aacattgccc ccatttcaca gaaaaggagc ctgagacaaa gattaagtga 1100

 tattttaagc aaagctgata atcccaggga aaattgctga tcaagtcttg 1150

 aaatccaaca catccttcgg agtaattttt aatgctttcg cttcttttac 1200

 ctaagccatg tgtgttccat atgaccttaa atctaagccc taatattgta 1250

 aatggagttc agaagacaac ttagtctccc attttctttc ctggcattca 1300

 ttcaaataaa aataggcacg taatactgta ctgtt 1335

<210> 4931
<211> 19
<212> PRT
<213> Homo sapien

<400> 4931
 Pro Val Arg Leu Ser Lys Pro Gln Pro Arg Leu Glu Gln Arg Asp
   1               5                  10                  15

 Cys Leu Val Gly


<210> 4932
<211> 351
<212> DNA
<213> Homo sapien

<400> 4932
 tgtaaagtag aagggaaaat taagaaagtt agatgatcaa cccaggaagt 50

 acaaaatctg cctaaagtta caaaaaagag gacaaaaggc attggaggat 100

 aataaattat caaagtaata ctacaggaaa atttccctag taaattatca 150

 aagtaatact aggggaaaat ttccctgaac tacaaaacaa aacaaaacaa 200

 aaaacagtag tctcttggtt gaatgaaaaa gaacccatac tactgagtga 250

 aatttcagac tatctggaca agtcacttag ctatttaatc ggttatacca 300

 cgagatactt atggagggta ttagaacaat taatgatagt ttcattaaaa 350

 g 351

<210> 4933
<211> 11
<212> PRT
<213> Homo sapien

<400> 4933
 Cys Lys Val Glu Gly Lys Ile Lys Lys Val Arg
   1               5                  10

<210> 4934
<211> 4358
<212> DNA
<213> Homo sapien

<400> 4934
 gtttttggag ctgcgacgcc aaacatggcg tgttcctaga agccgctttc 50

 ggcatcagta ggcggcggcg tggggtctgg cagcgtgggg agagggacca 100

 accgacgcca cttcgtgttg ggaagtggga gcgggagggc cgggcaattc 150

 ccgaccgaac caaacggttt ccatggatct caatagtgcc agcactgttg 200

 ttcttcaggt gttaacacag gccaccagtc aggatactgc tgtgttaaaa 250

 ccagctgagg agcagttgaa gcagtgggag acacagccag gtttctattc 300

 agtgttgctg aatattttca ccaaccacac tttggatata aatgtaaggt 350

 ggcttgctgt actgtatttt aaacatggaa ttgatcgcta ctggagacgt 400

 gtagcacctc atgctctctc agaggaggag aaaactactc tgcgtgcagg 450

 gctcatcacc aacttcaatg aaccaataaa ccagattgca actcagattg 500

 cagtgctcat tgcaaaagtt gctagattgg attgtcccag acagtggcct 550

 gaactaattc ccactcttat agagtctgtt aaagtccagg atgatcttcg 600

 acagcacaga gcattactta ccttctatca tgttaccaag acactggcat 650

 ctaaacgact tgctgctgat agaaaactat tttatgattt agcttctgga 700

 atttataatt ttgcctgctc tctgtggaat caccacacag acacattcct 750

 gcaagaagtt tcttctggca atgaagctgc aactttgagt tcactagaac 800

 gaacactgct atcattgaaa gtgctgcgta agttaactgt taatggattt 850

 gtggaacctc ataagaatat ggaggtgatg ggttttttac atggaatatt 900

 tgaacgtcta aaacagtttc tggaatgcag tagaagtata ggtacagata 950

 atgtttgtag agatagactg gaaaagacca tcattctttt tactaaagtg 1000

 cttttggact tcttggatca gcatcctttt tcatttactc ctctaattca 1050

 gagatcactg gaattttctg taagctatgt ttttacagaa gttggtgaag 1100

 gcgttacatt tgaacgattc attgtccaat gtatgaatct tattaagatg 1150

 attgtcaaaa attatgctta taagccatcc aaaaattttg aagatagcag 1200

 ccctgaaact cttgaagccc ataagattaa gatggcattc ttcacatatc 1250

 ctactttgac agagatatgt agaagattag tctctcatta tttcctatta 1300

 actgaagaag aactgacaat gtgggaagaa gacccagaag gctttacagt 1350

 ggaagaaaca ggaggagatt cttggaaata tagtttgagg ccatgcactg 1400

 aagtattatt tatagatata ttccatgaat acaatcagac tcttactcct 1450

 gtacttctag aaatgatgca aacacttcaa ggacccacaa atgtggaaga 1500

 tatgaatgca ctgttaatca aagatgctgt gtataatgct gttggattag 1550

 ctgcttatga gctctttgac agtgttgatt ttgatcagtg gtttaaaaac 1600

 cagcttcttc cagaattaca agtcattcac aataggtata agccattgcg 1650

 acgcagggtg atttggctca tcggtcagtg ggtttctgtg aaattcaagt 1700

 ctgacttaag acccatgctt tatgaagcaa tctgtaactt gcttcaagat 1750

 caagatttag tggtccgtat tgaaacagct acaactttga agttaactgt 1800

 tgatgatttt gaatttagaa cagatcagtt tctaccgtat ttggaaacca 1850

 tgttcacact actttttcag ttactgcagc aagctacaga atgtgacaca 1900

 aagatgcatg ttttgcatgt cctttcttgt gtgatcgaaa gagtcaacat 1950

 gcagatacga ccatatgtgg gatgtttggt acaatatttg cccctccttt 2000

 ggaagcagag tgaagaacac aatatgttga gatgtgctat tttgacaaca 2050

 cttattcatc ttgttcaggg attaggagca gacagcaaga acctgtaccc 2100

 tttcctgctc ccagttattc aactgagtac agatgtttca cagcctccac 2150

 atgtttatct tctggaagat ggtttagaat tatggttagt aactttggaa 2200

 aacagtccat gtattacacc agagttgctt cgtatatttc agaatatgtc 2250

 accacttctt gaactaagtt cagaaaatct tagaacttgc tttaagatca 2300

 tcaatggtta tatcttttta tcatcaacag aatttttaca gacatacgca 2350

 gtaggtctat gccagtcctt ttgtgaactt ttaaaggaaa ttactacaga 2400

 aggtcaagtt caggtgctca aggttgtgga aaatgccctt aaagtgaacc 2450

 caatactagg tccacaaatg tttcaaccga ttttacccta tgttttcaag 2500

 ggtattatag aaggggagag gtatcctgta gtgatgtcca cgtatcttgg 2550

 agttatgggt cgagttctac tacaaaacac tagttttttt tcttcactac 2600

 ttaatgagat ggcccataaa tttaatcagg agatggacca gcttttggga 2650

 aatatgattg aaatgtgggt tgatcgaatg gacaacatta cccagcctga 2700

 aagaagaaaa ctttcagctt tggctttgct ctctcttctg ccatctgata 2750

 atagtgttat ccaagataaa ttctgtggga ttataaacat ttcagtagaa 2800

 ggcctgcatg atgtcatgac ggaagatcct gaaacaggaa cttataaaga 2850

 ctgtatgttg atgtctcatc ttgaggaacc aaaagtaaca gaagatgaag 2900

 aaccacccac agaacaagat aagaggaaaa agatgctggc cctgaaggac 2950

 cctgttcata cagtgtcact gcagcagttc atctacgaga agctcaaggc 3000

 acagcaggag atgctaggag aacaaggttt ccagtccctc atggaaacag 3050

 tggatacgga gattgtcacc cagctacagg agtttttgca aggattctaa 3100

 gagcacatga catgtggctg cctccccttt cagaaacaag ctgagtaacc 3150

 cagcctgccg tttgtatgtg agagcctgct gagatgaaga aatcacttca 3200

 tgaaaataag caaagaccac acatttttta ctacaaaatg taaaggataa 3250

 atgtaaatcc tgcataacta aaatcacaaa cctattcctc aaaagaattt 3300

 aattttatat ttatgagggg gcccttcact aaaaagtaca tgtaaaagta 3350

 catttgatga caatagctgc ttagtttcct gttaagagaa gaaactttat 3400

 cttttaatta tgtgctctta atatttgaag atgagagtta atacctgaga 3450

 tgtttttctg caaccaaaat tcattaaatt tggctgcctt atcctttttt 3500

 taagctaatg aaactacagg tttgaaaaat gacaaagctg ttcagatgat 3550

 gctattaaag aaatgtgtgt actaagcaaa aatatataaa tagtgacaaa 3600

 tacacattac caagcttatc ttgcaaggga gttattttca tctaacatag 3650

 aaagtgtgtt ttatcagaca aatgctttta ttttcattct aataatttga 3700

 tacagaaatt agtaaaggca tttttttctt tttttttcca gtaaatacat 3750

 tgggtctata aatgtgcatt tgtaagggcc acaaaagtga acgtgtggta 3800

 ctgtagtacc acgtgggaga cctctggtta tggtttagtc ctagttcctt 3850

 tgttactcct gtgagcaccg agaagaactg ggcgactccc agtcccacct 3900

 gtgctgtgac agtcccacgt ggctatgaca gactgtttag tacttaccct 3950

 tctcaggttc ctcagtgcag gggtgcatca gggcctcaat aataggggta 4000

 tacctgggag gatccagcag taatccccag ggtactagga ttactagtac 4050

 tctgatggaa ctagtcttcc ttccttattc ctcgaacatg cagtacataa 4100

 aaaggggaaa aggagaaaaa aaaagcctta ctttgtttta cttgccattt 4150

 attgtaagga aactttaaag cattttttag gaaatactca aaagcaaggt 4200

 tggaaaatgt tttatctttc tatagaaagt tgggtacagt atgtaactgc 4250

 gggaaaccca ctgccccttt gtaagctgtg gaacccaaac tgtatgggga 4300

 tatttgatgt tttcagaaag aggaagaaaa tatggtccaa attaaatttt 4350

 ccaaagat 4358

<210> 4935
<211> 975
<212> PRT
<213> Homo sapien

<400> 4935
 Met Asp Leu Asn Ser Ala Ser Thr Val Val Leu Gln Val Leu Thr
   1               5                  10                  15

 Gln Ala Thr Ser Gln Asp Thr Ala Val Leu Lys Pro Ala Glu Glu
                  20                  25                  30

 Gln Leu Lys Gln Trp Glu Thr Gln Pro Gly Phe Tyr Ser Val Leu
                  35                  40                  45

 Leu Asn Ile Phe Thr Asn His Thr Leu Asp Ile Asn Val Arg Trp
                  50                  55                  60

 Leu Ala Val Leu Tyr Phe Lys His Gly Ile Asp Arg Tyr Trp Arg
                  65                  70                  75

 Arg Val Ala Pro His Ala Leu Ser Glu Glu Glu Lys Thr Thr Leu
                  80                  85                  90

 Arg Ala Gly Leu Ile Thr Asn Phe Asn Glu Pro Ile Asn Gln Ile
                  95                 100                 105

 Ala Thr Gln Ile Ala Val Leu Ile Ala Lys Val Ala Arg Leu Asp
                 110                 115                 120

 Cys Pro Arg Gln Trp Pro Glu Leu Ile Pro Thr Leu Ile Glu Ser
                 125                 130                 135

 Val Lys Val Gln Asp Asp Leu Arg Gln His Arg Ala Leu Leu Thr
                 140                 145                 150

 Phe Tyr His Val Thr Lys Thr Leu Ala Ser Lys Arg Leu Ala Ala
                 155                 160                 165

 Asp Arg Lys Leu Phe Tyr Asp Leu Ala Ser Gly Ile Tyr Asn Phe
                 170                 175                 180

 Ala Cys Ser Leu Trp Asn His His Thr Asp Thr Phe Leu Gln Glu
                 185                 190                 195

 Val Ser Ser Gly Asn Glu Ala Ala Thr Leu Ser Ser Leu Glu Arg
                 200                 205                 210

 Thr Leu Leu Ser Leu Lys Val Leu Arg Lys Leu Thr Val Asn Gly
                 215                 220                 225

 Phe Val Glu Pro His Lys Asn Met Glu Val Met Gly Phe Leu His
                 230                 235                 240

 Gly Ile Phe Glu Arg Leu Lys Gln Phe Leu Glu Cys Ser Arg Ser
                 245                 250                 255

 Ile Gly Thr Asp Asn Val Cys Arg Asp Arg Leu Glu Lys Thr Ile
                 260                 265                 270

 Ile Leu Phe Thr Lys Val Leu Leu Asp Phe Leu Asp Gln His Pro
                 275                 280                 285

 Phe Ser Phe Thr Pro Leu Ile Gln Arg Ser Leu Glu Phe Ser Val
                 290                 295                 300

 Ser Tyr Val Phe Thr Glu Val Gly Glu Gly Val Thr Phe Glu Arg
                 305                 310                 315

 Phe Ile Val Gln Cys Met Asn Leu Ile Lys Met Ile Val Lys Asn
                 320                 325                 330

 Tyr Ala Tyr Lys Pro Ser Lys Asn Phe Glu Asp Ser Ser Pro Glu
                 335                 340                 345

 Thr Leu Glu Ala His Lys Ile Lys Met Ala Phe Phe Thr Tyr Pro
                 350                 355                 360

 Thr Leu Thr Glu Ile Cys Arg Arg Leu Val Ser His Tyr Phe Leu
                 365                 370                 375

 Leu Thr Glu Glu Glu Leu Thr Met Trp Glu Glu Asp Pro Glu Gly
                 380                 385                 390

 Phe Thr Val Glu Glu Thr Gly Gly Asp Ser Trp Lys Tyr Ser Leu
                 395                 400                 405

 Arg Pro Cys Thr Glu Val Leu Phe Ile Asp Ile Phe His Glu Tyr
                 410                 415                 420

 Asn Gln Thr Leu Thr Pro Val Leu Leu Glu Met Met Gln Thr Leu
                 425                 430                 435

 Gln Gly Pro Thr Asn Val Glu Asp Met Asn Ala Leu Leu Ile Lys
                 440                 445                 450

 Asp Ala Val Tyr Asn Ala Val Gly Leu Ala Ala Tyr Glu Leu Phe
                 455                 460                 465

 Asp Ser Val Asp Phe Asp Gln Trp Phe Lys Asn Gln Leu Leu Pro
                 470                 475                 480

 Glu Leu Gln Val Ile His Asn Arg Tyr Lys Pro Leu Arg Arg Arg
                 485                 490                 495

 Val Ile Trp Leu Ile Gly Gln Trp Val Ser Val Lys Phe Lys Ser
                 500                 505                 510

 Asp Leu Arg Pro Met Leu Tyr Glu Ala Ile Cys Asn Leu Leu Gln
                 515                 520                 525

 Asp Gln Asp Leu Val Val Arg Ile Glu Thr Ala Thr Thr Leu Lys
                 530                 535                 540

 Leu Thr Val Asp Asp Phe Glu Phe Arg Thr Asp Gln Phe Leu Pro
                 545                 550                 555

 Tyr Leu Glu Thr Met Phe Thr Leu Leu Phe Gln Leu Leu Gln Gln
                 560                 565                 570

 Ala Thr Glu Cys Asp Thr Lys Met His Val Leu His Val Leu Ser
                 575                 580                 585

 Cys Val Ile Glu Arg Val Asn Met Gln Ile Arg Pro Tyr Val Gly
                 590                 595                 600

 Cys Leu Val Gln Tyr Leu Pro Leu Leu Trp Lys Gln Ser Glu Glu
                 605                 610                 615

 His Asn Met Leu Arg Cys Ala Ile Leu Thr Thr Leu Ile His Leu
                 620                 625                 630

 Val Gln Gly Leu Gly Ala Asp Ser Lys Asn Leu Tyr Pro Phe Leu
                 635                 640                 645

 Leu Pro Val Ile Gln Leu Ser Thr Asp Val Ser Gln Pro Pro His
                 650                 655                 660

 Val Tyr Leu Leu Glu Asp Gly Leu Glu Leu Trp Leu Val Thr Leu
                 665                 670                 675

 Glu Asn Ser Pro Cys Ile Thr Pro Glu Leu Leu Arg Ile Phe Gln
                 680                 685                 690

 Asn Met Ser Pro Leu Leu Glu Leu Ser Ser Glu Asn Leu Arg Thr
                 695                 700                 705

 Cys Phe Lys Ile Ile Asn Gly Tyr Ile Phe Leu Ser Ser Thr Glu
                 710                 715                 720

 Phe Leu Gln Thr Tyr Ala Val Gly Leu Cys Gln Ser Phe Cys Glu
                 725                 730                 735

 Leu Leu Lys Glu Ile Thr Thr Glu Gly Gln Val Gln Val Leu Lys
                 740                 745                 750

 Val Val Glu Asn Ala Leu Lys Val Asn Pro Ile Leu Gly Pro Gln
                 755                 760                 765

 Met Phe Gln Pro Ile Leu Pro Tyr Val Phe Lys Gly Ile Ile Glu
                 770                 775                 780

 Gly Glu Arg Tyr Pro Val Val Met Ser Thr Tyr Leu Gly Val Met
                 785                 790                 795

 Gly Arg Val Leu Leu Gln Asn Thr Ser Phe Phe Ser Ser Leu Leu
                 800                 805                 810

 Asn Glu Met Ala His Lys Phe Asn Gln Glu Met Asp Gln Leu Leu
                 815                 820                 825

 Gly Asn Met Ile Glu Met Trp Val Asp Arg Met Asp Asn Ile Thr
                 830                 835                 840

 Gln Pro Glu Arg Arg Lys Leu Ser Ala Leu Ala Leu Leu Ser Leu
                 845                 850                 855

 Leu Pro Ser Asp Asn Ser Val Ile Gln Asp Lys Phe Cys Gly Ile
                 860                 865                 870

 Ile Asn Ile Ser Val Glu Gly Leu His Asp Val Met Thr Glu Asp
                 875                 880                 885

 Pro Glu Thr Gly Thr Tyr Lys Asp Cys Met Leu Met Ser His Leu
                 890                 895                 900

 Glu Glu Pro Lys Val Thr Glu Asp Glu Glu Pro Pro Thr Glu Gln
                 905                 910                 915

 Asp Lys Arg Lys Lys Met Leu Ala Leu Lys Asp Pro Val His Thr
                 920                 925                 930

 Val Ser Leu Gln Gln Phe Ile Tyr Glu Lys Leu Lys Ala Gln Gln
                 935                 940                 945

 Glu Met Leu Gly Glu Gln Gly Phe Gln Ser Leu Met Glu Thr Val
                 950                 955                 960

 Asp Thr Glu Ile Val Thr Gln Leu Gln Glu Phe Leu Gln Gly Phe
                 965                 970                 975

<210> 4936
<211> 2672
<212> DNA
<213> Homo sapien

<400> 4936
 cttccagaga gcaatatggc tggttcccca acatgcctca ccctcatcta 50

 tatcctttgg cagctcacag ggtcagcagc ctctggaccc gtgaaagagc 100

 tggtcggttc cgttggtggg gccgtgactt tccccctgaa gtccaaagta 150

 aagcaagttg actctattgt ctggaccttc aacacaaccc ctcttgtcac 200

 catacagcca gaagggggca ctatcatagt gacccaaaat cgtaataggg 250

 agagagtaga cttcccagat ggaggctact ccctgaagct cagcaaactg 300

 aagaagaatg actcagggat ctactatgtg gggatataca gctcatcact 350

 ccagcagccc tccacccagg agtacgtgct gcatgtctac gagcacctgt 400

 caaagcctaa agtcaccatg ggtctgcaga gcaataagaa tggcacctgt 450

 gtgaccaatc tgacatgctg catggaacat ggggaagagg atgtgattta 500

 tacctggaag gccctggggc aagcagccaa tgagtcccat aatgggtcca 550

 tcctccccat ctcctggaga tggggagaaa gtgatatgac cttcatctgc 600

 gttgccagga accctgtcag cagaaacttc tcaagcccca tccttgccag 650

 gaagctctgt gaaggtgctg ctgatgaccc agattcctcc atggtcctcc 700

 tgtgtctcct gttggtgccc ctcctgctca gtctctttgt actggggcta 750

 tttctttggt ttctgaagag agagagacaa gaagagtaca ttgaagagaa 800

 gaagagagtg gacatttgtc gggaaactcc taacatatgc ccccattctg 850

 gagagaacac agagtacgac acaatccctc acactaatag aacaatccta 900

 aaggaagatc cagcaaatac ggtttactcc actgtggaaa taccgaaaaa 950

 gatggaaaat ccccactcac tgctcacgat gccagacaca ccaaggctat 1000

 ttgcctatga gaatgttatc tagacagcag tgcactcccc taagtctctg 1050

 ctcaaaaaaa aaacaattct cggcccaaag aaaacaatca gaagaattca 1100

 ctgatttgac tagaaacatc aaggaagaat gaagaacgtt gacttttttc 1150

 caggataaat tatctctgat gcttctttag atttaagagt tcataattcc 1200

 atccactgct gagaaatctc ctcaaaccca gaaggtttaa tcacttcatc 1250

 ccaaaaatgg gattgtgaat gtcagcaaac cataaaaaaa gtgcttagaa 1300

 gtattcctat agaaatgtaa atgcaaggtc acacatatta atgacagcct 1350

 gttgtattaa tgatggctcc aggtcagtgt ctggagtttc attccatccc 1400

 agggcttgga tgtaaggatt ataccaagag tcttgctacc aggagggcaa 1450

 gaagaccaaa acagacagac aagtccagca gaagcagatg cacctgacaa 1500

 aaatggatgt attaattggc tctataaact atgtgcccag cactatgctg 1550

 agcttacact aattggtcag acgtgctgtc tgccctcatg aaattggctc 1600

 caaatgaatg aactactttc atgagcagtt gtagcaggcc tgaccacaga 1650

 ttcccagagg gccaggtgtg gatccacagg acttgaaggt caaagttcac 1700

 aaagatgaag aatcagggta gctgaccatg tttggcagat actataatgg 1750

 agacacagaa gtgtgcatgg cccaaggaca aggacctcca gccaggcttc 1800

 atttatgcac ttgtgctgca aaagaaaagt ctaggtttta aggctgtgcc 1850

 agaacccatc ccaataaaga gaccgagtct gaagtcacat tgtaaatcta 1900

 gtgtaggaga cttggagtca ggcagtgaga ctggtggggc acggggggca 1950

 gtgggtactt gtaaaccttt aaagatggtt aattcattca atagatattt 2000

 attaagaacc tatgcggccc ggcatggtgg ctcacacctg taatcccagc 2050

 actttgggag gccaaggtgg gtgggtcatc tgaggtcagg agttcaagac 2100

 cagcctggcc aacatggtga aaccccatct ctactaaaga tacaaaaatt 2150

 tgctgagcgt ggtggtgtgc acctgtaatc ccagctactc gagaggccaa 2200

 ggcatgagaa tcgcttgaac ctgggaggtg gaggttgcag tgagctgaga 2250

 tggcaccact gcactccggc ctaggcaacg agagcaaaac tccaatacaa 2300

 acaaacaaac aaacacctgt gctaggtcag tctggcacgt aagatgaaca 2350

 tccctaccaa cacagagctc accatctctt atacttaagt gaaaaacatg 2400

 gggaagggga aaggggaatg gctgcttttg atatgttccc tgacacatat 2450

 cttgaatgga gacctcccta ccaagtgatg aaagtgttga aaaacttaat 2500

 aacaaatgct tgttgggcaa gaatgggatt gaggattatc ttctctcaga 2550

 aaggcattgt gaaggaattg agccagatct ctctccctac tgcaaaaccc 2600

 tattgtagta aaaaagtctt ctttactatc ttaataaaac agatattgtg 2650

 agattcaaaa aaaaaaaaaa aa 2672

<210> 4937
<211> 335
<212> PRT
<213> Homo sapien

<400> 4937
 Met Ala Gly Ser Pro Thr Cys Leu Thr Leu Ile Tyr Ile Leu Trp
   1               5                  10                  15

 Gln Leu Thr Gly Ser Ala Ala Ser Gly Pro Val Lys Glu Leu Val
                  20                  25                  30

 Gly Ser Val Gly Gly Ala Val Thr Phe Pro Leu Lys Ser Lys Val
                  35                  40                  45

 Lys Gln Val Asp Ser Ile Val Trp Thr Phe Asn Thr Thr Pro Leu
                  50                  55                  60

 Val Thr Ile Gln Pro Glu Gly Gly Thr Ile Ile Val Thr Gln Asn
                  65                  70                  75

 Arg Asn Arg Glu Arg Val Asp Phe Pro Asp Gly Gly Tyr Ser Leu
                  80                  85                  90

 Lys Leu Ser Lys Leu Lys Lys Asn Asp Ser Gly Ile Tyr Tyr Val
                  95                 100                 105

 Gly Ile Tyr Ser Ser Ser Leu Gln Gln Pro Ser Thr Gln Glu Tyr
                 110                 115                 120

 Val Leu His Val Tyr Glu His Leu Ser Lys Pro Lys Val Thr Met
                 125                 130                 135

 Gly Leu Gln Ser Asn Lys Asn Gly Thr Cys Val Thr Asn Leu Thr
                 140                 145                 150

 Cys Cys Met Glu His Gly Glu Glu Asp Val Ile Tyr Thr Trp Lys
                 155                 160                 165

 Ala Leu Gly Gln Ala Ala Asn Glu Ser His Asn Gly Ser Ile Leu
                 170                 175                 180

 Pro Ile Ser Trp Arg Trp Gly Glu Ser Asp Met Thr Phe Ile Cys
                 185                 190                 195

 Val Ala Arg Asn Pro Val Ser Arg Asn Phe Ser Ser Pro Ile Leu
                 200                 205                 210

 Ala Arg Lys Leu Cys Glu Gly Ala Ala Asp Asp Pro Asp Ser Ser
                 215                 220                 225

 Met Val Leu Leu Cys Leu Leu Leu Val Pro Leu Leu Leu Ser Leu
                 230                 235                 240

 Phe Val Leu Gly Leu Phe Leu Trp Phe Leu Lys Arg Glu Arg Gln
                 245                 250                 255

 Glu Glu Tyr Ile Glu Glu Lys Lys Arg Val Asp Ile Cys Arg Glu
                 260                 265                 270

 Thr Pro Asn Ile Cys Pro His Ser Gly Glu Asn Thr Glu Tyr Asp
                 275                 280                 285

 Thr Ile Pro His Thr Asn Arg Thr Ile Leu Lys Glu Asp Pro Ala
                 290                 295                 300

 Asn Thr Val Tyr Ser Thr Val Glu Ile Pro Lys Lys Met Glu Asn
                 305                 310                 315

 Pro His Ser Leu Leu Thr Met Pro Asp Thr Pro Arg Leu Phe Ala
                 320                 325                 330

 Tyr Glu Asn Val Ile
                 335

<210> 4938
<211> 2025
<212> DNA
<213> Homo sapien

<400> 4938
 cttctgtgtg tgcacatgtg taatacatat ctgggatcaa agctatctat 50

 ataaagtcct tgattctgtg tgggttcaaa cacatttcaa agcttcagga 100

 tcctgaaagg ttttgctcta cttcctgaag acctgaacac cgctcccata 150

 aagccatggc ttgccttgga tttcagcggc acaaggctca gctgaacctg 200

 gctaccagga cctggccctg cactctcctg ttttttcttc tcttcatccc 250

 tgtcttctgc aaagcaatgc acgtggccca gcctgctgtg gtactggcca 300

 gcagccgagg catcgccagc tttgtgtgtg agtatgcatc tccaggcaaa 350

 gccactgagg tccgggtgac agtgcttcgg caggctgaca gccaggtgac 400

 tgaagtctgt gcggcaacct acatgatggg gaatgagttg accttcctag 450

 atgattccat ctgcacgggc acctccagtg gaaatcaagt gaacctcact 500

 atccaaggac tgagggccat ggacacggga ctctacatct gcaaggtgga 550

 gctcatgtac ccaccgccat actacctggg cataggcaac ggaacccaga 600

 tttatgtaat tgatccagaa ccgtgcccag attctgactt cctcctctgg 650

 atccttgcag cagttagttc ggggttgttt ttttatagct ttctcctcac 700

 agctgtttct ttgagcaaaa tgctaaagaa aagaagccct cttacaacag 750

 gggtctatgt gaaaatgccc ccaacagagc cagaatgtga aaagcaattt 800

 cagccttatt ttattcccat caattgagaa accattatga agaagagagt 850

 ccatatttca atttccaaga gctgaggcaa ttctaacttt tttgctatcc 900

 agctattttt atttgtttgt gcatttgggg ggaattcatc tctctttaat 950

 ataaagttgg atgcggaacc caaattacgt gtactacaat ttaaagcaaa 1000

 ggagtagaaa gacagagctg ggatgtttct gtcacatcag ctccactttc 1050

 agtgaaagca tcacttggga ttaatatggg gatgcagcat tatgatgtgg 1100

 gtcaaggaat taagttaggg aatggcacag cccaaagaag gaaaaggcag 1150

 ggagcgaggg agaagactat attgtacaca ccttatattt acgtatgaga 1200

 cgtttatagc cgaaatgatc ttttcaagtt aaattttatg ccttttattt 1250

 cttaaacaaa tgtatgatta catcaaggct tcaaaaatac tcacatggct 1300

 atgttttagc cagtgatgct aaaggttgta ttgcatatat acatatatat 1350

 atatatatat atatatatat atatatatat atatatatat tttaatttga 1400

 tagtattgtg catagagcca cgtatgtttt tgtgtatttg ttaatggttt 1450

 gaatataaac actatatggc agtgtctttc caccttgggt cccagggaag 1500

 ttttgtggag gagctcagga cactaataca ccaggtagaa cacaaggtca 1550

 tttgctaact agcttggaaa ctggatgagg tcatagcagt gcttgattgc 1600

 gtggaattgt gctgagttgg tgttgacatg tgctttgggg cttttacacc 1650

 agttcctttc aatggtttgc aaggaagcca cagctggtgg tatctgagtt 1700

 gacttgacag aacactgtct tgaagacaat ggcttactcc aggagaccca 1750

 caggtatgac cttctaggaa gctccagttc gatgggccca attcttacaa 1800

 acatgtggtt aatgccatgg acagaagaag gcagcaggtg gcagaatggg 1850

 gtgcatgaag gtttctgaaa attaacactg cttgtgtttt taactcaata 1900

 ttttccatga aaatgcaaca acatgtataa tatttttaat taaataaaaa 1950

 tctgtggtgg tcgttttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2000

 aaaaaaaaaa aaaaaaaaaa aaaaa 2025

<210> 4939
<211> 223
<212> PRT
<213> Homo sapien

<400> 4939
 Met Ala Cys Leu Gly Phe Gln Arg His Lys Ala Gln Leu Asn Leu
   1               5                  10                  15

 Ala Thr Arg Thr Trp Pro Cys Thr Leu Leu Phe Phe Leu Leu Phe
                  20                  25                  30

 Ile Pro Val Phe Cys Lys Ala Met His Val Ala Gln Pro Ala Val
                  35                  40                  45

 Val Leu Ala Ser Ser Arg Gly Ile Ala Ser Phe Val Cys Glu Tyr
                  50                  55                  60

 Ala Ser Pro Gly Lys Ala Thr Glu Val Arg Val Thr Val Leu Arg
                  65                  70                  75

 Gln Ala Asp Ser Gln Val Thr Glu Val Cys Ala Ala Thr Tyr Met
                  80                  85                  90

 Met Gly Asn Glu Leu Thr Phe Leu Asp Asp Ser Ile Cys Thr Gly
                  95                 100                 105

 Thr Ser Ser Gly Asn Gln Val Asn Leu Thr Ile Gln Gly Leu Arg
                 110                 115                 120

 Ala Met Asp Thr Gly Leu Tyr Ile Cys Lys Val Glu Leu Met Tyr
                 125                 130                 135

 Pro Pro Pro Tyr Tyr Leu Gly Ile Gly Asn Gly Thr Gln Ile Tyr
                 140                 145                 150

 Val Ile Asp Pro Glu Pro Cys Pro Asp Ser Asp Phe Leu Leu Trp
                 155                 160                 165

 Ile Leu Ala Ala Val Ser Ser Gly Leu Phe Phe Tyr Ser Phe Leu
                 170                 175                 180

 Leu Thr Ala Val Ser Leu Ser Lys Met Leu Lys Lys Arg Ser Pro
                 185                 190                 195

 Leu Thr Thr Gly Val Tyr Val Lys Met Pro Pro Thr Glu Pro Glu
                 200                 205                 210

 Cys Glu Lys Gln Phe Gln Pro Tyr Phe Ile Pro Ile Asn
                 215                 220

<210> 4940
<211> 647
<212> DNA
<213> Homo sapien

<400> 4940
 gtttttctgc tgtgggtacg tgagcaggaa acatggagaa gaatcctttg 50

 gcagccccat tactaatcct ctggtttcat cttgactgcg tgagcagcat 100

 actgaacgtg gaacaaagtc ctcagtcact gcatgttcag gagggagaca 150

 gcaccaattt cacctgcagc ttcccttcca gcaattttta tgccttacac 200

 tggtacagat gggaaactgc aaaaagcccc gaggccttgt ttgtaatgac 250

 tttaaatggg gatgaaaaga agaaaggacg aataagtgcc actcttaata 300

 ccaaggaggg ttacagctat ttgtacatca aaggatccca gcctgaagac 350

 tcagccacat acctctgtgc cttcccgggc agctggggga aattgcagtt 400

 tggagcaggg acccaggttg tggtcacccc agatatccag aaccctgacc 450

 ctgccgtgta ccagctgaga gactctaaat ccagtgacaa gtctgtctgc 500

 ctattcaccg attttgattc tcaaacaaat gtgtcacaaa gtaaggattc 550

 tgatgtgtat atcacagaca aaactgtgct agacactgag gtctatggac 600

 ttcaagagca acagtgctgt gggctggagc aacaaatctg actttgg 647

<210> 4941
<211> 202
<212> PRT
<213> Homo sapien

<400> 4941
 Met Glu Lys Asn Pro Leu Ala Ala Pro Leu Leu Ile Leu Trp Phe
   1               5                  10                  15

 His Leu Asp Cys Val Ser Ser Ile Leu Asn Val Glu Gln Ser Pro
                  20                  25                  30

 Gln Ser Leu His Val Gln Glu Gly Asp Ser Thr Asn Phe Thr Cys
                  35                  40                  45

 Ser Phe Pro Ser Ser Asn Phe Tyr Ala Leu His Trp Tyr Arg Trp
                  50                  55                  60

 Glu Thr Ala Lys Ser Pro Glu Ala Leu Phe Val Met Thr Leu Asn
                  65                  70                  75

 Gly Asp Glu Lys Lys Lys Gly Arg Ile Ser Ala Thr Leu Asn Thr
                  80                  85                  90

 Lys Glu Gly Tyr Ser Tyr Leu Tyr Ile Lys Gly Ser Gln Pro Glu
                  95                 100                 105

 Asp Ser Ala Thr Tyr Leu Cys Ala Phe Pro Gly Ser Trp Gly Lys
                 110                 115                 120

 Leu Gln Phe Gly Ala Gly Thr Gln Val Val Val Thr Pro Asp Ile
                 125                 130                 135

 Gln Asn Pro Asp Pro Ala Val Tyr Gln Leu Arg Asp Ser Lys Ser
                 140                 145                 150

 Ser Asp Lys Ser Val Cys Leu Phe Thr Asp Phe Asp Ser Gln Thr
                 155                 160                 165

 Asn Val Ser Gln Ser Lys Asp Ser Asp Val Tyr Ile Thr Asp Lys
                 170                 175                 180

 Thr Val Leu Asp Thr Glu Val Tyr Gly Leu Gln Glu Gln Gln Cys
                 185                 190                 195

 Cys Gly Leu Glu Gln Gln Ile
                 200

<210> 4942
<211> 426
<212> DNA
<213> Homo sapien

<400> 4942
 agaacaatga agacatttgc tggattttcg ttcctgtttt tgtggctgca 50

 gctggactgt atgagtagag gagaggatgt ggagcagagt cttttcctga 100

 gtgtccgaga gggagacagc tccgttataa actgcactta cacagacagc 150

 tcctccacct acttatactg gtataagcaa gaacctggag caggtctcca 200

 gttgctgacg tatatttttt caaatatgga catgaaacaa gaccaaagac 250

 tcactgttct attgaataaa aaggataaac atctgtctct gcgcattgca 300

 gacacccaga ctggggactc agctatctac ttctgtgcag agaagaactc 350

 taagttggga ggaagctaca tacctacatt tggaagagga accagcctta 400

 ttgttcatcc gtatatccag aaccct 426

<210> 4943
<211> 139
<212> PRT
<213> Homo sapien

<400> 4943
 Met Lys Thr Phe Ala Gly Phe Ser Phe Leu Phe Leu Trp Leu Gln
   1               5                  10                  15

 Leu Asp Cys Met Ser Arg Gly Glu Asp Val Glu Gln Ser Leu Phe
                  20                  25                  30

 Leu Ser Val Arg Glu Gly Asp Ser Ser Val Ile Asn Cys Thr Tyr
                  35                  40                  45

 Thr Asp Ser Ser Ser Thr Tyr Leu Tyr Trp Tyr Lys Gln Glu Pro
                  50                  55                  60

 Gly Ala Gly Leu Gln Leu Leu Thr Tyr Ile Phe Ser Asn Met Asp
                  65                  70                  75

 Met Lys Gln Asp Gln Arg Leu Thr Val Leu Leu Asn Lys Lys Asp
                  80                  85                  90

 Lys His Leu Ser Leu Arg Ile Ala Asp Thr Gln Thr Gly Asp Ser
                  95                 100                 105

 Ala Ile Tyr Phe Cys Ala Glu Lys Asn Ser Lys Leu Gly Gly Ser
                 110                 115                 120

 Tyr Ile Pro Thr Phe Gly Arg Gly Thr Ser Leu Ile Val His Pro
                 125                 130                 135

 Tyr Ile Gln Asn


<210> 4944
<211> 735
<212> DNA
<213> Homo sapien

<400> 4944
 atgacagtga agaccctgca tggcccagcc atggtcaagt acttgctgct 50

 gtcgatattg gggcttgcct ttctgagtga ggcggcagct cggaaaatcc 100

 ccaaagtagg acatactttt ttccaaaagc ctgagagttg cccgcctgtg 150

 ccaggaggta gtatgaagct tgacattggc atcatcaatg aaaaccagcg 200

 cgtttccatg tcacgtaaca tcgagagccg ctccacctcc ccctggaatt 250

 acactgtcac ttgggacccc aaccggtacc cctcggaagt tgtacaggcc 300

 cagtgtagga acttgggctg catcaatgct caaggaaagg aagacatctc 350

 catgaattcc gttcccatcc agcaagagac cctggtcgtc cggaggaagc 400

 accaaggctg ctctgtttct ttccagttgg agaaggtgct ggtgactgtt 450

 ggctgcacct gcgtcacccc tgtcatccac catgtgcagt aagaggtgca 500

 tatccactca gctgaagaag ctgtagaaat gccactcctt acccagtgct 550

 ctgcaacaag tcctgtctga cccccaattc cctccacttc acaggactct 600

 taataagacc tgcacggatg gaaacagaaa atattcacaa tgtatgtgtg 650

 tatgtactac actttatatt tgatatctaa aatgttagga gaaaaattaa 700

 tatattcagt gctaatataa taaagtatta ataat 735

<210> 4945
<211> 163
<212> PRT
<213> Homo sapien

<400> 4945
 Met Thr Val Lys Thr Leu His Gly Pro Ala Met Val Lys Tyr Leu
   1               5                  10                  15

 Leu Leu Ser Ile Leu Gly Leu Ala Phe Leu Ser Glu Ala Ala Ala
                  20                  25                  30

 Arg Lys Ile Pro Lys Val Gly His Thr Phe Phe Gln Lys Pro Glu
                  35                  40                  45

 Ser Cys Pro Pro Val Pro Gly Gly Ser Met Lys Leu Asp Ile Gly
                  50                  55                  60

 Ile Ile Asn Glu Asn Gln Arg Val Ser Met Ser Arg Asn Ile Glu
                  65                  70                  75

 Ser Arg Ser Thr Ser Pro Trp Asn Tyr Thr Val Thr Trp Asp Pro
                  80                  85                  90

 Asn Arg Tyr Pro Ser Glu Val Val Gln Ala Gln Cys Arg Asn Leu
                  95                 100                 105

 Gly Cys Ile Asn Ala Gln Gly Lys Glu Asp Ile Ser Met Asn Ser
                 110                 115                 120

 Val Pro Ile Gln Gln Glu Thr Leu Val Val Arg Arg Lys His Gln
                 125                 130                 135

 Gly Cys Ser Val Ser Phe Gln Leu Glu Lys Val Leu Val Thr Val
                 140                 145                 150

 Gly Cys Thr Cys Val Thr Pro Val Ile His His Val Gln
                 155                 160

<210> 4946
<211> 653
<212> DNA
<213> Homo sapien

<400> 4946
 ccctgatatg aagaaaagat gattcttact gtgggcttta gctttttgtt 50

 tttctgtaag tagattcatt tgtttacatt ccacttgctc tataacccca 100

 tttctccttc tctgactctt gaaggctttt tctcttgcac tcttggtttt 150

 tggttatttg ctgcctttgg ctttatttct gtgtccttct cttgcctctg 200

 ctcattgagt tcttctgggc taggcatgtg ctgtactcac tgtctggggg 250

 gtgcagaatt cactatttcc tcattgtctt tttcccagac aggggcacgc 300

 tgtgtgacaa agtaacccag agttccccgg accagacggt ggcgagtggc 350

 agtgaggtgg tactgctctg cacttacgac actgtatatt caaatccaga 400

 tttattctgg taccggataa ggccagatta ttcctttcag tttgtctttt 450

 atggggataa cagcagatca gaaggtgcag attttactca aggacggttt 500

 tctgtgaaac acattctgac ccagaaagcc tttcacttgg tgatctctcc 550

 agtaaggact gaagacagtg ccacttacta ctgtgccttt agcactatga 600

 tgcaggtgcc caggaagtca taacacaaac tcctggggca cagctcagca 650

 gag 653

<210> 4947
<211> 113
<212> PRT
<213> Homo sapien

<400> 4947
 Met Ile Leu Thr Val Gly Phe Ser Phe Leu Phe Phe Tyr Arg Gly
   1               5                  10                  15

 Thr Leu Cys Asp Lys Val Thr Gln Ser Ser Pro Asp Gln Thr Val
                  20                  25                  30

 Ala Ser Gly Ser Glu Val Val Leu Leu Cys Thr Tyr Asp Thr Val
                  35                  40                  45

 Tyr Ser Asn Pro Asp Leu Phe Trp Tyr Arg Ile Arg Pro Asp Tyr
                  50                  55                  60

 Ser Phe Gln Phe Val Phe Tyr Gly Asp Asn Ser Arg Ser Glu Gly
                  65                  70                  75

 Ala Asp Phe Thr Gln Gly Arg Phe Ser Val Lys His Ile Leu Thr
                  80                  85                  90

 Gln Lys Ala Phe His Leu Val Ile Ser Pro Val Arg Thr Glu Asp
                  95                 100                 105

 Ser Ala Thr Tyr Tyr Cys Ala Phe
                 110

<210> 4948
<211> 7320
<212> DNA
<213> Homo sapien

<400> 4948
 cgctgctggg gttaggattc tgcgcggcga ggcaagatgc tcaagtccaa 50

 gacgttctta aaaaagaccc gggcgggcgg cgtgatgaag atcgtgcgcg 100

 agcactacct gcgagacgac atcggctgcg gtgcgcccgg gtgcgcagcg 150

 tgtggagggg cgcacgaggg gccggccctg gagccgcagc cccaggaccc 200

 ggcgagcagc gtctgcccgc aaccgcacta cttgctgccc gacactaatg 250

 tgttactgca ccagattgat gttcttgagg accctgccat caggaatgta 300

 attgtgctac aaacagttct tcaagaagtg agaaatcgca gtgcccccgt 350

 atataaacgc atccgagatg tgactaataa ccaagagaag catttctata 400

 ctttcactaa tgagcaccat agagaaacct atgtagaaca agaacaggga 450

 gaaaatgcta atgacaggaa tgatagagcg attcgagtag cagcaaaatg 500

 gtacaatgaa catttgaaaa aaatgtcagc agacaaccag ctgcaagtta 550

 tcttcataac aaatgacagg agaaacaaag agaaagccat agaagaagga 600

 ataccagctt tcacttgtga agaatatgta aagagcctaa ctgctaaccc 650

 cgaactcata gatcgtcttg cttgtttgtc tgaagaaggg aatgaaatag 700

 aaagtggaaa aataatattt tcagagcatc ttcccttaag taagctacag 750

 caaggcataa aatctggtac ataccttcaa ggaacattta gagctagcag 800

 ggaaaattac ttggaagcta cagtatggat tcatggcgac agtgaagaaa 850

 ataaagagat aatcttacag ggacttaaac atttaaacag agctgttcac 900

 gaagatattg tggctgtgga gcttctcccc aagagtcagt gggtagcacc 950

 atcttctgtg gttttacatg atgaaggtca aaatgaagaa gatgtggaga 1000

 aagaagaaga gacagaacga atgcttaaga ctgctgtaag cgagaaaatg 1050

 ttgaagccta caggtagagt tgtaggaata ataaaaagga attggagacc 1100

 atattgtggc atgctttcca agtctgacat taaggagtca agaagacatc 1150

 tctttacacc tgctgataag agaatccctc gaattcgcat agaaaccaga 1200

 caggcttcca cattagaagg acggagaatt attgttgcta ttgatggttg 1250

 gcccagaaat tccagatatc caaatggaca ctttgtgaga aatttaggtg 1300

 atgttggaga gaaagagact gaaacagaag ttttgttact tgaacacgat 1350

 gttccccatc agcctttttc acaggctgtt cttagttttc tgccaaagat 1400

 gccctggagc attactgaaa aggacatgaa aaaccgagaa gacctgaggc 1450

 atctgtgtat ttgtagtgta gacccaccag gatgtactga tatagacgat 1500

 gctctacatt gtcgagaact cgaaaatgga aatttggagg ttggtgttca 1550

 tattgctgat gtgagccatt ttattaggcc aggaaatgcc ttggatcaag 1600

 aatcagccag aagaggaaca actgtgtatc tttgtgaaaa gaggattgac 1650

 atggttccag agttgcttag ctctaacttg tgttccttaa aatgtgacgt 1700

 ggacaggctg gcattttcat gtatttggga aatgaatcac aatgctgaaa 1750

 tcttaaaaac gaagtttacc aaaagtgtta ttaattcaaa ggcatctctg 1800

 acatatgctg aagctcagtt gagaattgat tcagcaaaca tgaatgatga 1850

 tattaccact agtctccgtg gactgaataa actagccaaa attctgaaga 1900

 aaagaaggat tgaaaaaggg gctttgactc tatcctctcc tgaagttcga 1950

 ttccacatgg acagtgaaac tcacgatcct atagatctgc agaccaagga 2000

 acttagggaa acaaattcca tggttgaaga atttatgtta cttgccaata 2050

 tttctgttgc aaaaaaaatt catgaggaat tttctgaaca tgctctgctt 2100

 cgaaaacatc ctgctccacc tccatcaaat tatgaaattc ttgttaaggc 2150

 agccaggtca aggaatttgg aaattaagac tgatacagcc aagtctttgg 2200

 ctgagtcttt ggatcaggcc gaatctccta cttttccata tctaaacact 2250

 ctgttgagaa tattagccac tcgctgtatg atgcaagctg tgtacttctg 2300

 ttctggaatg gataatgatt ttcatcacta tggcttagcg tctccaatat 2350

 acacacattt tacttcaccc attagaagat acgcagatgt cattgttcat 2400

 cggcttttgg ctgtggctat tggggctgac tgtacttatc cagagttgac 2450

 agacaaacac aagcttgcag atatatgtaa aaatctaaat ttccggcaca 2500

 aaatggctca atatgcccaa cgtgcatcag tggcttttca tacccagtta 2550

 ttcttcaaaa gcaaaggaat agtaagtgaa gaagcctata ttttatttgt 2600

 aagaaagaat gccattgtgg tattaattcc aaagtatggt ttagaaggga 2650

 cagtcttttt tgaagaaaag gacaaaccaa acccacagct tatttatgat 2700

 gatgagatac cctcacttaa aatagaagat acagtgttcc atgtatttga 2750

 taaagttaaa gtgaaaatca tgttagactc atctaatctt caacatcaga 2800

 agatccgaat gtccctggta gaaccacaga taccaggaat aagcattcct 2850

 actgatactt caaacatgga ccttaatgga ccaaagaaaa agaagatgaa 2900

 gcttggaaaa tagctatatt caacaaaaat cttcaaagac tggtttcttt 2950

 tttaaaagaa aaaacttgaa agaacacttc taagcctaag tgtgtgatac 3000

 agtttgttac ttttaagtac attttaataa tttcagacat ctgcattttt 3050

 attgaacagt tgactgtatc tgacccatca tactactata cttctgggtt 3100

 gaacagaatt atttatgcag aataattcaa ttgaatatcc atcacttaaa 3150

 tacagtgaca ggacagcaac ttcagggatc tgtaaagatc atttaaatgg 3200

 agtgctcatc tcattgagga gcagattaat tttgcgtaag tactttgatt 3250

 atttaatatt tgtaagaaaa aactttcatt ttcctacaga ggaaaataga 3300

 acaattttag aagcaaggaa caatctcttt tctaagtctt ggaagctgtc 3350

 agtgttgagg atgtaatctc ctttgccatc tttaattcac ctaacttaca 3400

 ctaggtgttc tcttactgtc tttaaaagct tcctgtattt tattagtggt 3450

 ccttgaaaaa ctgtgaatgt ttgggaattg gtagaaaggc aaaaagtagg 3500

 atattttgac ctgactggaa agatggttgt gtttttattg ccaggtaata 3550

 agtgtgatca ttgttgaact tcagctccag tgtctctcca gaataagaca 3600

 ttggcattca aatgtctata tcttgttact tacaaaataa aaaacagata 3650

 attagtggct tttaaattgt agttatatca gtgtatatac acgaggggaa 3700

 ctgtataaag acatactaaa gggaacagat taaaataagt attattaata 3750

 aaatttggtg tgccagactg actacttccc ttgctaatca cagagattag 3800

 taatgattaa attaatatct tcaggaatat tttgggatag ggttgcctta 3850

 aaacatttta cttggcttat tcaatttcta aagcacttac gttgtgccag 3900

 gttccactca agtaaactat ctctgccttc aaggagcttg cagtatagtg 3950

 agaaaagcct gccaagtaaa tcagcaggta tactaaatag gtagtcattt 4000

 aggcactcaa taaatgttga ctaatttttc cagtttccta ttactgagga 4050

 aaacctccat acactgaggc agaaacttgt gtcagttgga ggaaaataga 4100

 cttgagtagt ctttggtcca ggtaaaatgg gtcagtagac actgaaacag 4150

 tagagtagga gtcaaaaagc cttttctgtg aagtgctaga acattttaga 4200

 ctttgttggc tatggtctgt attgcaacta tagtacacaa ctctgccgtt 4250

 gatagtgtgt aaggagccat atacaatatg taaacaaatc aacatgactg 4300

 tgtttcaaca aggcctgatt tgttaagttt catatatagt catatgtcac 4350

 ttaatgacag ggatatgttc tgagacatgt cacttggcaa tttcatcatt 4400

 gtgtgaaaat catgatgtag ttacacaaac ctagatggta taccctatgg 4450

 tatcctatat gggatagcct attgctccta acctacaaac ctgtatggca 4500

 tattactgta ctgattactg taggcagttg taacacagtg ctaagtattt 4550

 gtgtatctaa acatatctaa acatagaaaa ggtacagtaa aaatatatat 4600

 atagatatat ataagatata aaatggtaca cctatttagg acatttacca 4650

 tgaacaagtt ggcaggactg gaagctggct ctgggtgagt cagtaagtgg 4700

 ttagtgaatg tgaaggccat gatattactg tgcactactg tagactttta 4750

 taaacactat atacttaggc tacataaagt aatttcacta tgatgttacc 4800

 atggctgtgt ccgcaggcaa taggaatttt tcagctccat tgtaatctta 4850

 cgggatcatc atcgtatatt tggccattgt tgaccaaaag ttatgcagca 4900

 catcattata attttgatgt gtcacaaaac attactcatt tgatttcccc 4950

 cacccccgcc aaccatttaa aaaagtttgc cggctaggtg cggtggctca 5000

 tgcctgtaat cctagcattt tgggaggacg aggcgggtgg atcactcgat 5050

 gtcaggagtt tgagaccagc ctggccaaca tggtaaaacg ccgtctctac 5100

 taaaaataca aaaacttagc tgggtgtaac ggcggatgcc tgtaatccca 5150

 gctacttggg aggctgaggc aggagaatcg cttgaacctg ggaggcggaa 5200

 gttgcagtga gccgagattg caccactgca gttcagcctg gatgatgaga 5250

 gtgagactcc atcgcaaaaa aaaaaaaaaa aaaaagaaaa gaaaattagc 5300

 caggtgtggt ggcaagtgcc tttaatccca cctcaggagg ctgaggcagg 5350

 agaatcgctt gaacctggga ggcagaggtt gcagtgagcc aagatcgcgc 5400

 cactgcactc cagcctgggt gacagaacaa gactgtctca aaaaaaaaaa 5450

 aaaagaagaa aaactgccta caggccatag ttaacctgca atagagaaga 5500

 aagggaagta gggcagtgca tgactggcct taggtttttt ctttccaagt 5550

 ttattttctt gtgcttcagc tactagaaag gtttaattca gggataagtc 5600

 ccaattgagt agttcaagat gatcagagac tttgctattt tcccctaagt 5650

 tctattccat aatctaaaat gttctgtttc tagtgccagt tcttatgcta 5700

 agcaggttac gtggaatata tcacttaact caaaaagccc tgttaagcca 5750

 ggactgttat ctccatttaa cagatgagaa aatggaggtt tatggtctgt 5800

 tctcacactg ctacgaagaa ataccccaaa ctgggtaatt attataaagg 5850

 aaagaggttt aatggactca gttccgcatt gctggtgagg cctcaggaca 5900

 cttatacaat catggcagaa aaaggagaag caggcacctt tttcacaggg 5950

 cggcaggatg aaaatgactg ccagcagtgg aaatgccaga cgcttataaa 6000

 accttcagat ctcatgagac cggctcacta tcacaggaac agcatggagg 6050

 aaaccgcccc catgatccag ttacctccac ctggtcccac ccttgacacg 6100

 tggggattgc tacaattcaa ggttagattt gggtgaggac acagagccat 6150

 accatatcag cccagatcaa gtagtgacag agtagggatt tgaatacagg 6200

 ttatagtcac tattgtgtta tttcttgact tttgtactat taaaaaactg 6250

 tagccagtga ggcttctacc cttagtaccc agaactcctt ttaggtatag 6300

 caattgtttt taggtaaatt tatattgagt ttaacacctg tgtgattaaa 6350

 gacaactttc caatgtagta tctgtagcca tgtcccctaa tggctattag 6400

 tgttcatggt tagtgtgttg aagatgagcc aggtacataa cgcggcacat 6450

 tttctgcagg tcagcagtaa ggtttcaagg tacagttatg gaggaaagaa 6500

 gaaaatgaca cattgataac acaggtcttt attccctttt gaatgagaca 6550

 gtttttaaaa gttgatttat aaatacaaaa atacattctc caaagatagt 6600

 atttccaaac tgttatatac ccatctactc ccaacatgga tataagtttt 6650

 ttaaaaaaat agttgtatat aacatacata tctgccccag tgttacttca 6700

 caggcctatg ccctacggga actccactct cccagcccca ctttttctct 6750

 tggttctccc acattcttat tctcccacat ccctacccac gtttgagctg 6800

 gaaaggatgt ccctacccta ggcatgaggt atattttatt ctgggcacca 6850

 cacatttgcc ccatagataa caatacacgt gatgatgtca ctagtactac 6900

 ctttctagta tttacatact taaaagtagt aactagaaca gttatcactg 6950

 gaactaagaa ttttccccac agaggtgaac aggaccaagg aactaaaatt 7000

 tcaggaaacc tgtttaattt cttttgtatc tttgaaaagt tagttttata 7050

 tctaagattt cttcacatag gttataattc atctgtatgt tcaagctttt 7100

 atgtaaaaat atatagtgcc ttcagtttta acatagtttc acatgttctc 7150

 agaactgcta aattcagtgc taccagtaag gcttaataag tagttcattg 7200

 accctgtaag ataggagcac tcagctctgt cacaatttgt tgttaaacac 7250

 atcactcaat gtaagtataa aaatatttat tgataaaaaa taaacttata 7300

 attcagcaaa aaaaaaaaaa 7320

<210> 4949
<211> 958
<212> PRT
<213> Homo sapien

<400> 4949
 Met Leu Lys Ser Lys Thr Phe Leu Lys Lys Thr Arg Ala Gly Gly
   1               5                  10                  15

 Val Met Lys Ile Val Arg Glu His Tyr Leu Arg Asp Asp Ile Gly
                  20                  25                  30

 Cys Gly Ala Pro Gly Cys Ala Ala Cys Gly Gly Ala His Glu Gly
                  35                  40                  45

 Pro Ala Leu Glu Pro Gln Pro Gln Asp Pro Ala Ser Ser Val Cys
                  50                  55                  60

 Pro Gln Pro His Tyr Leu Leu Pro Asp Thr Asn Val Leu Leu His
                  65                  70                  75

 Gln Ile Asp Val Leu Glu Asp Pro Ala Ile Arg Asn Val Ile Val
                  80                  85                  90

 Leu Gln Thr Val Leu Gln Glu Val Arg Asn Arg Ser Ala Pro Val
                  95                 100                 105

 Tyr Lys Arg Ile Arg Asp Val Thr Asn Asn Gln Glu Lys His Phe
                 110                 115                 120

 Tyr Thr Phe Thr Asn Glu His His Arg Glu Thr Tyr Val Glu Gln
                 125                 130                 135

 Glu Gln Gly Glu Asn Ala Asn Asp Arg Asn Asp Arg Ala Ile Arg
                 140                 145                 150

 Val Ala Ala Lys Trp Tyr Asn Glu His Leu Lys Lys Met Ser Ala
                 155                 160                 165

 Asp Asn Gln Leu Gln Val Ile Phe Ile Thr Asn Asp Arg Arg Asn
                 170                 175                 180

 Lys Glu Lys Ala Ile Glu Glu Gly Ile Pro Ala Phe Thr Cys Glu
                 185                 190                 195

 Glu Tyr Val Lys Ser Leu Thr Ala Asn Pro Glu Leu Ile Asp Arg
                 200                 205                 210

 Leu Ala Cys Leu Ser Glu Glu Gly Asn Glu Ile Glu Ser Gly Lys
                 215                 220                 225

 Ile Ile Phe Ser Glu His Leu Pro Leu Ser Lys Leu Gln Gln Gly
                 230                 235                 240

 Ile Lys Ser Gly Thr Tyr Leu Gln Gly Thr Phe Arg Ala Ser Arg
                 245                 250                 255

 Glu Asn Tyr Leu Glu Ala Thr Val Trp Ile His Gly Asp Ser Glu
                 260                 265                 270

 Glu Asn Lys Glu Ile Ile Leu Gln Gly Leu Lys His Leu Asn Arg
                 275                 280                 285

 Ala Val His Glu Asp Ile Val Ala Val Glu Leu Leu Pro Lys Ser
                 290                 295                 300

 Gln Trp Val Ala Pro Ser Ser Val Val Leu His Asp Glu Gly Gln
                 305                 310                 315

 Asn Glu Glu Asp Val Glu Lys Glu Glu Glu Thr Glu Arg Met Leu
                 320                 325                 330

 Lys Thr Ala Val Ser Glu Lys Met Leu Lys Pro Thr Gly Arg Val
                 335                 340                 345

 Val Gly Ile Ile Lys Arg Asn Trp Arg Pro Tyr Cys Gly Met Leu
                 350                 355                 360

 Ser Lys Ser Asp Ile Lys Glu Ser Arg Arg His Leu Phe Thr Pro
                 365                 370                 375

 Ala Asp Lys Arg Ile Pro Arg Ile Arg Ile Glu Thr Arg Gln Ala
                 380                 385                 390

 Ser Thr Leu Glu Gly Arg Arg Ile Ile Val Ala Ile Asp Gly Trp
                 395                 400                 405

 Pro Arg Asn Ser Arg Tyr Pro Asn Gly His Phe Val Arg Asn Leu
                 410                 415                 420

 Gly Asp Val Gly Glu Lys Glu Thr Glu Thr Glu Val Leu Leu Leu
                 425                 430                 435

 Glu His Asp Val Pro His Gln Pro Phe Ser Gln Ala Val Leu Ser
                 440                 445                 450

 Phe Leu Pro Lys Met Pro Trp Ser Ile Thr Glu Lys Asp Met Lys
                 455                 460                 465

 Asn Arg Glu Asp Leu Arg His Leu Cys Ile Cys Ser Val Asp Pro
                 470                 475                 480

 Pro Gly Cys Thr Asp Ile Asp Asp Ala Leu His Cys Arg Glu Leu
                 485                 490                 495

 Glu Asn Gly Asn Leu Glu Val Gly Val His Ile Ala Asp Val Ser
                 500                 505                 510

 His Phe Ile Arg Pro Gly Asn Ala Leu Asp Gln Glu Ser Ala Arg
                 515                 520                 525

 Arg Gly Thr Thr Val Tyr Leu Cys Glu Lys Arg Ile Asp Met Val
                 530                 535                 540

 Pro Glu Leu Leu Ser Ser Asn Leu Cys Ser Leu Lys Cys Asp Val
                 545                 550                 555

 Asp Arg Leu Ala Phe Ser Cys Ile Trp Glu Met Asn His Asn Ala
                 560                 565                 570

 Glu Ile Leu Lys Thr Lys Phe Thr Lys Ser Val Ile Asn Ser Lys
                 575                 580                 585

 Ala Ser Leu Thr Tyr Ala Glu Ala Gln Leu Arg Ile Asp Ser Ala
                 590                 595                 600

 Asn Met Asn Asp Asp Ile Thr Thr Ser Leu Arg Gly Leu Asn Lys
                 605                 610                 615

 Leu Ala Lys Ile Leu Lys Lys Arg Arg Ile Glu Lys Gly Ala Leu
                 620                 625                 630

 Thr Leu Ser Ser Pro Glu Val Arg Phe His Met Asp Ser Glu Thr
                 635                 640                 645

 His Asp Pro Ile Asp Leu Gln Thr Lys Glu Leu Arg Glu Thr Asn
                 650                 655                 660

 Ser Met Val Glu Glu Phe Met Leu Leu Ala Asn Ile Ser Val Ala
                 665                 670                 675

 Lys Lys Ile His Glu Glu Phe Ser Glu His Ala Leu Leu Arg Lys
                 680                 685                 690

 His Pro Ala Pro Pro Pro Ser Asn Tyr Glu Ile Leu Val Lys Ala
                 695                 700                 705

 Ala Arg Ser Arg Asn Leu Glu Ile Lys Thr Asp Thr Ala Lys Ser
                 710                 715                 720

 Leu Ala Glu Ser Leu Asp Gln Ala Glu Ser Pro Thr Phe Pro Tyr
                 725                 730                 735

 Leu Asn Thr Leu Leu Arg Ile Leu Ala Thr Arg Cys Met Met Gln
                 740                 745                 750

 Ala Val Tyr Phe Cys Ser Gly Met Asp Asn Asp Phe His His Tyr
                 755                 760                 765

 Gly Leu Ala Ser Pro Ile Tyr Thr His Phe Thr Ser Pro Ile Arg
                 770                 775                 780

 Arg Tyr Ala Asp Val Ile Val His Arg Leu Leu Ala Val Ala Ile
                 785                 790                 795

 Gly Ala Asp Cys Thr Tyr Pro Glu Leu Thr Asp Lys His Lys Leu
                 800                 805                 810

 Ala Asp Ile Cys Lys Asn Leu Asn Phe Arg His Lys Met Ala Gln
                 815                 820                 825

 Tyr Ala Gln Arg Ala Ser Val Ala Phe His Thr Gln Leu Phe Phe
                 830                 835                 840

 Lys Ser Lys Gly Ile Val Ser Glu Glu Ala Tyr Ile Leu Phe Val
                 845                 850                 855

 Arg Lys Asn Ala Ile Val Val Leu Ile Pro Lys Tyr Gly Leu Glu
                 860                 865                 870

 Gly Thr Val Phe Phe Glu Glu Lys Asp Lys Pro Asn Pro Gln Leu
                 875                 880                 885

 Ile Tyr Asp Asp Glu Ile Pro Ser Leu Lys Ile Glu Asp Thr Val
                 890                 895                 900

 Phe His Val Phe Asp Lys Val Lys Val Lys Ile Met Leu Asp Ser
                 905                 910                 915

 Ser Asn Leu Gln His Gln Lys Ile Arg Met Ser Leu Val Glu Pro
                 920                 925                 930

 Gln Ile Pro Gly Ile Ser Ile Pro Thr Asp Thr Ser Asn Met Asp
                 935                 940                 945

 Leu Asn Gly Pro Lys Lys Lys Lys Met Lys Leu Gly Lys
                 950                 955

<210> 4950
<211> 2705
<212> DNA
<213> Homo sapien

<400> 4950
 tttttttttt ttttttggtg gtttagccaa gagctggctc agctggacag 50

 caaggcttct ggctaacgca gcatttttgg cagcctaagc tgttcccagg 100

 gcgcttagca cacagatctt ggccttcaaa atgcagactt tggccctcag 150

 aatgcatgct ccctggcact gttactaggc ttggagatcc cctcataaat 200

 ttcttcttat ttagggaaat taggtgttcc ctggtctttc ttgggctgac 250

 ccataagtat gtaacatgtc atcaatacca tctatgcttt tcaaccaact 300

 tcaaatcaaa gaaacaggtt accttcagac tgttaagtat gagagatcaa 350

 atctttcgag cacagtaaca gtgccatgtg aagatgttgt gtgcaatttg 400

 cctgactctt tttgacttag aacagaattg gccatagtta cagcatagag 450

 ctttgctgct gcagctgcta ctgctgctgc taccagtact acctctatta 500

 ctactgactg atgtttattg cagacttact gtgtaggaca gtcttttaaa 550

 ttctttccag gaatttagtc ttttaaattt tcaacaaccc taggaggttg 600

 ataatattat tatcaccatt ttaaagatga taaaagggag atgctgagag 650

 atcatgtaat ttgcctggtc actctgagag tggatggata gtgtttcatt 700

 gtattggtct cggtgagaac ttattttctt tttatgaaaa attattatta 750

 tttcttggga cagggtctca ctttgtcacc caggctggag tgcagtagta 800

 cgatctcggc tcactgcaac ctccacctcc tgggttcaag caattctcct 850

 gtcgcagcct cccccgtagc tgggactaca ggcacgtgcc accatgactg 900

 gctaattttt gtatttttag tagagacagg gtttcaccat attggtcaga 950

 ctggtcttga attcctgacc tcaggtgatc cacccacctt ggcctccaaa 1000

 agtgctggga ttacaggcgt gagccactgc gcctggccaa cttttctcct 1050

 taatgatatg cgtcattcat tcaataaaaa tttagtgatc atcttctatg 1100

 tgccagctat atcctagaag ttggagatat attatagtga atgaaacagt 1150

 atagatccct gctgtgatag agcttacatt ttacagggaa gaaatataca 1200

 agcaagtaag caattaataa agaaaatcat tccagttcct gacagaaaaa 1250

 acacagtggt atgataaaga acgattgcat tggagaagct gctttagatt 1300

 agatttgatt ggcagggaag tcctctcata accaagacct gaatggcaag 1350

 aaggagcctg ccatgtaagg atctggggag agaatgactc aggtagagaa 1400

 caaaagccaa agccctctgc cattcaggag tttggtgtgt ccaggaacaa 1450

 aagagctatg aagagaagtt cttccaccaa acatacaaaa tcaggatatg 1500

 caacttctag agttcccatc tggaagtaat aagagaatgt atcaaaacat 1550

 gggcacttct ggtccccaac tttcctctca cacccctcca acctcatttt 1600

 gagagaacaa ttcacatttt aatttttgat ggccattccc aaatggtata 1650

 gtttgtttgt taataatgac tttattgaga tacaattcat agaccataaa 1700

 attcgcccct ttaaagtata caattctgtg attttttagg atattcactg 1750

 ttgcataacc atcactacga tctaattcag aatattttca tcattccaaa 1800

 aagaaactcc gagtttaaca agatttcttg agatcaatat gcaaaaaatc 1850

 atttgtattt ctctacacta gcaatgagca atccaaaaat aaaattaaga 1900

 aaacaactcc atttacaaaa gcacaaaaaa taataaaata ttttggagta 1950

 aatttaacaa attaaatgta agacttgtac attgaaaact gcaaaacatc 2000

 attgaaataa attaaaggag acttaaatga aaagacatcc catgtgcatg 2050

 gattggaaga tttaatattg ttaagataat gcagtaaata gaataatggt 2100

 ccccaaaaga attctatgtc taatctccag aacctgtgaa tatgctacct 2150

 tacctggcaa aaggaactgg tagatgtgat aaagttatga agattatctt 2200

 gggttatcta catggaccta atgtaatcac aagaatcctt atgaaggaga 2250

 caaaaaggtc aaaggcagaa gaaggaaatg cgacaaagaa agcagaggtt 2300

 ggaatgatat actttgcaga tggaggaagg ggctgtgagt caggaaatac 2350

 aggctgcctc tagaagcttc aaagacaaga aaatgaatac tcccctgcag 2400

 cctccagaag tacagccctg ctgacacctt tattttagcc atataaggca 2450

 cattttggta ttctgactcc cagaactgta agataataaa cttgtattgt 2500

 tttaaacacc cagtctgtga gtttgttaca gcagcagtag gaaactaata 2550

 tacatgacaa tagttcccaa attaatctac aaattcaaca caatcccttg 2600

 caaagtccca gctggctttt ttacagaaat tgacaaactg atcctaaaat 2650

 tcatatgaaa atgaaaggga gaagccaaaa caatcctgaa aaaaaaaaaa 2700

 aaaaa 2705

<210> 4951
<211> 127
<212> PRT
<213> Homo sapien

<400> 4951
 Met Lys Asn Tyr Tyr Tyr Phe Leu Gly Gln Gly Leu Thr Leu Ser
   1               5                  10                  15

 Pro Arg Leu Glu Cys Ser Ser Thr Ile Ser Ala His Cys Asn Leu
                  20                  25                  30

 His Leu Leu Gly Ser Ser Asn Ser Pro Val Ala Ala Ser Pro Val
                  35                  40                  45

 Ala Gly Thr Thr Gly Thr Cys His His Asp Trp Leu Ile Phe Val
                  50                  55                  60

 Phe Leu Val Glu Thr Gly Phe His His Ile Gly Gln Thr Gly Leu
                  65                  70                  75

 Glu Phe Leu Thr Ser Gly Asp Pro Pro Thr Leu Ala Ser Lys Ser
                  80                  85                  90

 Ala Gly Ile Thr Gly Val Ser His Cys Ala Trp Pro Thr Phe Leu
                  95                 100                 105

 Leu Asn Asp Met Arg His Ser Phe Asn Lys Asn Leu Val Ile Ile
                 110                 115                 120

 Phe Tyr Val Pro Ala Ile Ser
                 125

<210> 4952
<211> 410
<212> DNA
<213> Homo sapien

<400> 4952
 atgaagttgg tgacaagcat tactgtactc ctatctttgg gtattatggg 50

 tgatgctaag accacacagc caaattcaat ggagagtaac gaagaagagc 100

 ctgttcactt gccttgtaac cactccacaa tcagtggaac tgattacata 150

 cattggtatc gacagcttcc ctcccagggt ccagagtacg tgattcatgg 200

 tcttacaagc aatgtgaaca acagaatggc ctctctggca atcgctgaag 250

 acagaaagtc cagtaccttg atcctgcacc gtgctacctt gagagatgct 300

 gctgtgtact actgcatcag agccaatgct ggtggtacta gctatggaaa 350

 gctgacattt ggacaaggga ccatcttgac tgtccatcca aatatccaga 400

 accctgaccc 410

<210> 4953
<211> 135
<212> PRT
<213> Homo sapien

<400> 4953
 Met Lys Leu Val Thr Ser Ile Thr Val Leu Leu Ser Leu Gly Ile
   1               5                  10                  15

 Met Gly Asp Ala Lys Thr Thr Gln Pro Asn Ser Met Glu Ser Asn
                  20                  25                  30

 Glu Glu Glu Pro Val His Leu Pro Cys Asn His Ser Thr Ile Ser
                  35                  40                  45

 Gly Thr Asp Tyr Ile His Trp Tyr Arg Gln Leu Pro Ser Gln Gly
                  50                  55                  60

 Pro Glu Tyr Val Ile His Gly Leu Thr Ser Asn Val Asn Asn Arg
                  65                  70                  75

 Met Ala Ser Leu Ala Ile Ala Glu Asp Arg Lys Ser Ser Thr Leu
                  80                  85                  90

 Ile Leu His Arg Ala Thr Leu Arg Asp Ala Ala Val Tyr Tyr Cys
                  95                 100                 105

 Ile Arg Ala Asn Ala Gly Gly Thr Ser Tyr Gly Lys Leu Thr Phe
                 110                 115                 120

 Gly Gln Gly Thr Ile Leu Thr Val His Pro Asn Ile Gln Asn Pro
                 125                 130                 135

<210> 4954
<211> 545
<212> DNA
<213> Homo sapien

<400> 4954
 ggcatctctg tagaaacata atgtatattg tttgcaatta ttgtgtattc 50

 ctaggcctgt ggggtagaaa catgagtggt tttttctcta acaaagggac 100

 gactggggag agtggggggc ccatgaaaag atgatttaaa ttctgggtac 150

 gaagtgtccc ctacccaatc tgtcttctct gttctgactg ctgtcttttt 200

 tcacaggggt ttggagccaa cagaaggagg tggagcagga tcctggacca 250

 ctcagtgttc cagagggagc cattgtttct ctcaactgca cttacagcaa 300

 cagtgctttt caatacttca tgtggtacag acagtattcc agaaaaggcc 350

 ctgagttgct gatgtacaca tactccagtg gtaacaaaga agatggaagg 400

 tttacagcac aggtcgataa atccagcaag tatatctcct tgttcatcag 450

 agactcacag cccagtgatt cagccaccta cctctgtgca atgagcgcac 500

 agtgctcccc agacacttgc ttgcagtctg tacccaaacc cagga 545

<210> 4955
<211> 111
<212> PRT
<213> Homo sapien

<400> 4955
 Met Tyr Ile Val Cys Asn Tyr Cys Val Phe Leu Gly Leu Trp Gly
   1               5                  10                  15

 Val Trp Ser Gln Gln Lys Glu Val Glu Gln Asp Pro Gly Pro Leu
                  20                  25                  30

 Ser Val Pro Glu Gly Ala Ile Val Ser Leu Asn Cys Thr Tyr Ser
                  35                  40                  45

 Asn Ser Ala Phe Gln Tyr Phe Met Trp Tyr Arg Gln Tyr Ser Arg
                  50                  55                  60

 Lys Gly Pro Glu Leu Leu Met Tyr Thr Tyr Ser Ser Gly Asn Lys
                  65                  70                  75

 Glu Asp Gly Arg Phe Thr Ala Gln Val Asp Lys Ser Ser Lys Tyr
                  80                  85                  90

 Ile Ser Leu Phe Ile Arg Asp Ser Gln Pro Ser Asp Ser Ala Thr
                  95                 100                 105

 Tyr Leu Cys Ala Met Ser
                 110

<210> 4956
<211> 7338
<212> DNA
<213> Homo sapien

<400> 4956
 ctcgatcact gggccgtgca cagcctcttg aattccctcc ccttcctggg 50

 cctggactca ggttcccagg gagggggaag cccctcaggg tgatcaagtt 100

 ataggggctt ggggggggcc cactcttagg tgtggaaaaa acagcaaagc 150

 acgtagggtg gtatgttcaa aactggaggc ggtgttggtg gaatggaaac 200

 agctcctggg ctgggaagca ggggcttggg ttccactgac tcattgggtg 250

 aacttggatg agtctctgct cctctggggg ccgcagtttc ggcttctgta 300

 taaggggggg tcttcccagc tgtgtcattc tccaatctat ttcacagatg 350

 gctgactcca aaaggcatca aattcaacca ggaggtcaag gccccttggc 400

 aggtcccccc tgtgccattg acccctgagg gtcccatgca ggctggccag 450

 ctgatgagtt tacaacacag ggtgggggcg gggcagcctc tccccctgca 500

 tgactgtcat agctccttac ttgagctgac tcataacgga gcccaaattg 550

 cgtcatggag gctcagccaa ggaaaccaat gtttatgatg ccctcacccc 600

 gtgcctgtcc ctttgaagaa ggtgttatcc ccattttaca gggaagaaaa 650

 ctgaggccca gagaaaggaa gtgactttcc ccagggtctg gctgctcaga 700

 ttcagcagag ctggggctgg aagccaaatc tgactctaga gctctgtggc 750

 tgtcaccata aacctgcttc ctctctggcc aaattagaac tcttgtcccc 800

 accaccccca ccctcagcac caattgaccc accattcagg gacagaagac 850

 tgaatcttca tgaggcttga gatgaggctg agtgagcgtt tccaaggcca 900

 tcttctgcac atgtgccttg ggcagaaaca agtctctttg ggaccttgga 950

 ccagcccatc ctcttccagg gatgtcccca ccccatcctt gttggcctac 1000

 agaggctact gtgagtcaga ggctggtgct aggttctagc cccaagcctg 1050

 gggtccctgg gagaggccag gggttggtgg ccaggctgca gagggacttt 1100

 ctgaagtctt catttaaagg gcatggaagg gcactctggt gtcatgccca 1150

 aggtcggggc tggtgagtca gaggctgaag ttccaatccc attccagaat 1200

 accacatgac cttagacaag ctggcgtcac caccctgggc ctcgcagcct 1250

 ggcctgtgaa atgggagagt agagcttgca agggaaatgg taaaagccgc 1300

 cacctttccc ccactctcca ccctctctcc catcctgaca tgactttggg 1350

 gaacatgcaa gtatagggtt caatcgtctt catgactttt ctacttttga 1400

 gcctctctgg gccttgactc ctcaaggaca tgaagacaca aagggcgctt 1450

 ctggtgaggg gaacagcatg agcgaaggcc cggaggcagg gaagctcccg 1500

 agcatcatgc tggggcagag acccccaagg ggatgcgcag gtggcaacaa 1550

 gaggagtaaa gggccctgaa tgacatgctg gggactcagc ccccagccct 1600

 gcagagggcc ccccagtgcg ggcaggccac caggtttcca caggaaggcc 1650

 cttctcggtg ggcaggccga ggccaggcgt gagtgctggc aatgccactt 1700

 catgtgtttc ccgttgtact tagtcccaac tcccataaaa gccccagagg 1750

 tgccacccag ccacacatgt ggacacctct ccctggcaac aatggtggtg 1800

 gacaatggca gggagtcagc cgcagcccag gggcgaggtg gcatggcagg 1850

 gagctctccg gccgctggtg gatccgggct ctgggcactc ggtgaggggc 1900

 ccgcggggct cctagcccgc ccaggccaat gctggcctta attaagaagg 1950

 agtctcccac ccaggagcca aaccaccctc ctggccacgc ccactgcaac 2000

 cgctttcagt tctgtttctt gggccgcgtg ctgaggccag cctcacaaat 2050

 aaaagccatc acttttctat ttctctctct ctctctcttt cttttttttt 2100

 tttttctttt ccaaaaagag aggcagccac aagatcttct aaaaggccgt 2150

 gacatcacgg cccaggtgac cgcggcccag ccaatgagcc aaggccgcga 2200

 gcaggcttct cgcatcctgt gagctgaggt tgggttgaca ctgggaaggc 2250

 ctggtccctc aaccacagaa ccacaaggcc aggcccttgc cgcctccagg 2300

 gccctgcgcg ggagctggtt ggctcctggt gctccccacc cccggccgcc 2350

 ctcgtaccca ccagagcctg ggctctgtca agggtaagcc tcattcattc 2400

 attccccgtg gcactggagg cggcccactc tgctctgtca gcttcggagc 2450

 tcctccaccc tggctgccga aagccccttc ccgccatcta atgatacact 2500

 ctgcatacgc ttctgttgag aatttgtggc tagacattcc tgtgggaccg 2550

 ggaatccaaa ttcttgggta caaacagaaa cttactttcc ttggggattt 2600

 ttttctctct ctcactcaca cacactctcg cgttctttcc ttttttcttt 2650

 ttcgtagcag caggggggaa aaaagagaca aaaacaaaac aaaaaacaac 2700

 aaaaagcaac acccccccct tttattttca aaagtagcta gaggaaaaaa 2750

 aaataaaaca acagccaacc aagtgaatcc caacccaacc ccctgaaggg 2800

 ctgaaaattc tcgccttctt cagagcgggg catggcatcg aacagcatct 2850

 tcgactcctt cccgacctac tcgccgacct tcatccgcgg tgagtaacaa 2900

 tagcccaggg ccctgggtgg ggagctgtgg ccaggccccg gaccacgtcc 2950

 ctccactgac cgccctggct gccctcaagc gcacagcctg tccgcctaaa 3000

 tccgctggcc tctgaaagcc tgaggtggga agaggggttg gtggtctctg 3050

 tggtctcttg gcgtggaaca tcgctgtggc actttcatcc tccgctggtg 3100

 gggacagtaa gccgtggggg cgatggatac tccaagacct caagacctca 3150

 aagggcagcc ctcagagggg ccaagggaaa ctctcaggga ccctcggctt 3200

 gctgcttcac taacagggcc ccagggcctg cagccccagc ccctgtcctg 3250

 cctgggactc cccacctggg ctcaggaggt cactgctggc aacttctggg 3300

 gagagctgtg ggatgcaggg gtcttcctgg agaccaccgc caacattttg 3350

 tgtgtaactc ctggggtatc agaagcagag ggaggagaag gaagccacag 3400

 gcttttgtgg aaaactgcac agagctgggc tgcactgaag ctggacctgc 3450

 acggggcagg gggacagacc tcgagaaagt tcgtggattt ggccacggaa 3500

 gaggagaaag tgtttctggg cagcttttgc cttttttggt ggctgcaggg 3550

 atgcagagtt ctgggttgtg tctcccagca aggatagggg gtctgggatc 3600

 cccgacctgg agcctctaat ggggctggga ctcatgggga gacttctcct 3650

 gcctctgtct ggcatttagg gctgatgcac cctggcctca gacaccccct 3700

 gctgccttcc tcctccctag caggagccca gatggggctg tgacacctga 3750

 gactggggat caagagtccc tgagctcaag tcccacggct cagtggcttc 3800

 cttgctgaga gaccttagga ggggagttac ttaacctctc tgtgccccaa 3850

 atagagtccc ctctgcttgt ggaattctca ttgtctgagc ctgggggtgg 3900

 accatgtata agggcagtgc ctctggatgg ttccagaaca gagaggctgc 3950

 atgagatcta gaacttcagg gttgggggct ggtgctgcct ttcctcagcc 4000

 gaggcagtca gcagagatgc agaggtgggt ctgcctgcct gcctaccctc 4050

 cagcccattg gcctgccctg ccgctggctg accgagtgat tcagggctgc 4100

 tgcctgggtg gccggctcgg ggcagggacc cagacacatt tgggtgtttg 4150

 agtcctcagg cttctgggaa ggcttgtctg agagcggggc ctgttcttct 4200

 tccctggtga ggccaaggaa ggctgtgctg ctgcagatgg ggactgagtc 4250

 ggggagtgaa gggggcctgc tgtcccctga aatgggggca ctcccatcaa 4300

 acctagctgt agctgatgat gagcggcagc cccaggtctg agagctgaga 4350

 gctgtggctg cttccttgga gttgctgcta ttataacgtt gttccctttg 4400

 tagtcctcgg agctaattaa aggcagttct gtggcaagaa aataagagtt 4450

 tataaaatcc atttgccggg tctttgtaat ctgtatttct ccttccgtgc 4500

 gcaagatgga gaaatgtagg gtttaaaaca aaggaacctt gggagacagg 4550

 gctagagccc cggtcggcct gggctgggtc ctgatcctcg gagcctggga 4600

 ggtggctggc agtagcacaa agggcacaaa gggagaggtg gctttggccc 4650

 aacatgtcat gtatgcgccc agagacagga ggccgctggg cagagcgggc 4700

 tgatcctggc cagcagtggc acagaaggcg cctcataggc tagggtctgt 4750

 ggagatgttt ggatctgggg tctgtggccc gagggccttc cctccacttt 4800

 tgtggagacc tgtctcccct cttcagcctt ctctctcctg ttcatttctg 4850

 ctcacgacgt gctcgccatg ggggcctgtc tcccaaatcc catccctgga 4900

 ggcttacagg gctccagctg ccaattcctt cctcaaagag acgcagcccc 4950

 agggtcccat ttgcagggtg ccaaccccac gctgccccct acagggtccc 5000

 taacccaccg acccttggca gtctcaggga accttcaggt tcctcctcgg 5050

 agttgcgttt ttaaacgcgt aagacaaaat ccaaaggatt acaaaggaaa 5100

 agaaatcgat ggaaatacca ttgtcaaact cagaaagcaa gctggtgaca 5150

 tattgactca cgttttccat ttgttgaact ccatttgtct gtgcctcttc 5200

 aagaactcac tgagtgacaa gaccccgcgg tgggccatgc agttgtgatg 5250

 agcatgaaca atatttcagg tcatccctga ccccgctgtg ataccagaga 5300

 acacctgtga tttccactgg tggaaaatcg ccatggaata tgatgctaaa 5350

 tttcagctag aggccaggga aaggaaagac acggttatct ccagcccagt 5400

 gtcacagacc ccctaaatta tacgcaagac aaaaactcca ggtccatccg 5450

 ggtctcgggt tctcagaatc ttactcgggc tgttctctcg tccacaggct 5500

 tttaccagaa ggggaagggt ctccctgtgc cccccactgc ctcctcttcc 5550

 tcctacctgt gtcttccaaa tgccatccca tctcagtccc tgagcaaagt 5600

 gtgatggagc cagcaggttt tctgaaatca ccgcccctag agagttttaa 5650

 acactggatt cccagttcct acctcaggct gtggaggatt ctccattcct 5700

 acctcagact gcggaatcag aatctctagg gtttgggcct gggcaggtgt 5750

 ggttttgcaa atcccctaaa gcgattctga tgtgcctctc aggcaggctt 5800

 ggggactgct gccagggaag cccagtcccc tacctgcctc tgccgcctgt 5850

 gtgctgtgag actgtgtctg agtcacttga catctctgga tccgtgttct 5900

 ctcatgagta aaagggcacg agtgagttgc atttggtgcc tcctatgtgg 5950

 gcttctctgt ctcccccacc tgacaaccca gggtggtccc tagaattatc 6000

 accgagctcc tactacctca gggtccccat agaccaacgg aagatgactt 6050

 cccttttgtc ttcactggca aaaacaggct gagaatgaag catcccatcc 6100

 atgcctctgc cttcaggcac ctgtactcag ccagtgccac agcctgtgca 6150

 ggggccttca aggcagcaag ggagagatcc agacccctgg agagtccgac 6200

 tgcttgtgca tgacattccc acggctccca cccagccctc ccctctcagt 6250

 ttctctgact ttgagctaag ggatcagaaa ctcccctcag ttcactgtgg 6300

 agagaagggg tgtgggaaaa gggtggagag gcatttggtt cccatcctgc 6350

 agtagaggcg tgagcaggag gtgagaagag ggcaacgcct accctcaggg 6400

 ctggtgcatg gatggtggaa ttctagaagc tggaatggaa ggtgtgagag 6450

 ggcacagggg ccccctgggg tctaccccca ggcaggacaa gggggattta 6500

 ttctccctgt gtgacaaatg gggaagctga gacctaagag ctgtgatcca 6550

 gacactctgt gtaactaagg acaagtccct tcctctctct gggcctcagt 6600

 ttccccgtct gacaattatg ggccaatggc cctgaggacc ccttgcccat 6650

 gcacggttcc actgggggcc agaaccttca ttctgaatct gcctcatgag 6700

 gccctcctct gcaccccctg gggcaccccc ccctcacacc aggtcacctt 6750

 tgctgaaccc tcacttgtac ccccacaggc aaacactcac cagggacact 6800

 ggcagtgggt gcccctccag ggagggaagc caaggaaatg ggcccaaact 6850

 gccacatgta ggctttaagg gggctctggg gcggcggggg ggcaaacgcg 6900

 ttcatctgtt tagtcagtca tttcccaaaa acttatcgag gtgtagagta 6950

 tcgagattcc agcttgggct ttagagccag gctctccagg ttcaagtcct 7000

 gactctgccc tctgccgtca cctgcatgag ttacttcact tctctgtctc 7050

 tggtttcctc atctgtaggg gttacaccaa ccttgcagag ctatggagag 7100

 aattaaagga gcatgatgcc tggcacagag tagttgctca ataagcattt 7150

 tccatttgat gaacaccatg agcatggcct tgtactggga gcccggggga 7200

 aactgggtca ggatctccat cctaagagct caccatctgg tgtagaaaaa 7250

 gatgggtcaa cagaaaattg ccctggggcg tgacaaaggt tttttgggag 7300

 aagaaccagg gctgtgagtt caaagagggg tactagcc 7338

<210> 4957
<211> 18
<212> PRT
<213> Homo sapien

<400> 4957
 Met Ala Ser Asn Ser Ile Phe Asp Ser Phe Pro Thr Tyr Ser Pro
   1               5                  10                  15

 Thr Phe Ile


<210> 4958
<211> 1074
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 691-721
<223> Unknown base

<400> 4958
 tttgtaaatc tgaaaactca ggattgagta gtctttcctt agctgcagtt 50

 gcctgtctgg ccacacctgc cagctgttgc ttgtacccct gtaatttgca 100

 cggccttccg ggcctttctc acaagatcac tgcaggtcac attcatgagg 150

 aaaatgcagg cagttcctgc catcagaccc ctcaggatgt catggtttgg 200

 cctgaaaaca agattcctgc aactctaatt ttcctttgct agatcaaatg 250

 aaggatttga tctaatgttt gcattctagc agcaaaatca ttgaatattt 300

 tatttcttaa gagccctgcc taaccaccgc ccccctcctc ccccgcgatc 350

 acacacacct gggttaggcc ctgcctctca cgcctgtgcc tcctgccaag 400

 tcctcagagg tctctgatcc catgtgcctc caggcatggc atagggggac 450

 tgtgacacag cctctcggcc cacagacccc tgattgtggg cttgctcact 500

 gccccagtca gtcctcttat tgaggattcc gtgccagttc ctgcctctgc 550

 cttcctgaga ttacaggtat gagccactgt gttaagcaaa aaaacttttt 600

 taaatgaaaa tcatttttta aaagacaggc tttccagggg agggtattat 650

 tccacttata tgaagtgtca acagagcaaa actcgatctc nnnnnnnnnn 700

 nnnnnnnnnn nnnnnnnnnn ngcagctctc tctctcggga gagggagggg 750

 acttccgaga ggaaaaggcc tgcaagagcc tttgggttaa ctgagaaagc 800

 acagcccggc caacgcttgg gaagaaagac aggcaagcac tggaaacagg 850

 agctattagg gtgaggagag agccttgcct ttcacagcac agtgaggatg 900

 acattgcacc agggacagag attgtatgtg acaaggctgg ggctccttct 950

 ttcctagaca atcaaagtat cagtgatggg ttttggttgg tgattttgaa 1000

 aaaaaaaaaa agtatgttat gttatactag tgtatgctgt actgaattga 1050

 aataaaacca aaatctgcat cttc 1074

<210> 4959
<211> 79
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 691-721
<223> Unknown amino acid

<400> 4959
 Cys Lys Ser Glu Asn Ser Gly Leu Ser Ser Leu Ser Leu Ala Ala
   1               5                  10                  15

 Val Ala Cys Leu Ala Thr Pro Ala Ser Cys Cys Leu Tyr Pro Cys
                  20                  25                  30

 Asn Leu His Gly Leu Pro Gly Leu Ser His Lys Ile Thr Ala Gly
                  35                  40                  45

 His Ile His Glu Glu Asn Ala Gly Ser Ser Cys His Gln Thr Pro
                  50                  55                  60

 Gln Asp Val Met Val Trp Pro Glu Asn Lys Ile Pro Ala Thr Leu
                  65                  70                  75

 Ile Phe Leu Cys


<210> 4960
<211> 3120
<212> DNA
<213> Homo sapien

<400> 4960
 gtgagaccag gactgagaac agggagaggc gacccgaccc ccagggcccg 50

 gtgctcagga cagcacacag agccgctgaa aacgactgaa gagagcaagg 100

 gatttcctgg gacatctggc tctggagagt aaaaggccaa gctatgatag 150

 caactggtgg agtgataact ggcctggccg ccttgaaaag gcaagactct 200

 gccagatcac agcagcatgt caacctcagc ccgtctcctg ctacccaaga 250

 gaagaagccc atcaggcgcc ggccccgggc agatgttgtg gttgttcgtg 300

 gcaaaatccg gctttattcc ccatctggtt tttttcttat tttaggagtg 350

 ctcatctcca ttataggaat tgccatggcc gttcttggat attggcccca 400

 aaaagaacat tttattgatg ctgaaacaac actgtcaaca aatgaaactc 450

 aggtcattcg gaatgaaggc ggtgtggtgg ttcgcttctt tgagcagcat 500

 ttgcattctg ataagatgaa aatgcttggc ccgttcacca tggggattgg 550

 cattttcatt ttcatttgtg ctaatgccat tcttcatgaa aaccgtgaca 600

 aagagaccaa aatcatacac atgagggata tctattccac agtcattgac 650

 attcacacgc taagaatcaa ggagcaaagg caaatgaacg gcatgtacac 700

 tggtttgatg ggagaaacag aagtaaaaca gaatgggagc tcctgtgcct 750

 cgagattggc agcaaatacg atcgcctctt tctcgggttt tcggagcagt 800

 tttcgaatgg acagctccgt ggaggaggat gaacttatgt taaatgaagg 850

 taagagttct gggcatctta tgcccccttt gctctctgac agctctgtgt 900

 ctgtctttgg cctctatcca cctccttcca agacaactga tgataagacc 950

 agcggctcta agaaatgtga aaccaagtca attgtgtcat cgtccatcag 1000

 tgcttttaca ttgcctgtga tcaaacttaa taactgtgtt attgatgagc 1050

 ccagtataga taacatcact gaagatgctg acaacctcaa aagtaggtca 1100

 aggaatttgt caatggattc ccttgtggtt cctttgccca acaccagtga 1150

 atccttccag cccgtcagca cagtgctacc aaggaataat tccattgggg 1200

 agtcgttgtc gagtcagtac aagtcatcta tggctctcgg acctggggct 1250

 ggacagctct tgtctcctgg ggctgccaga agacagtttg ggtccaatac 1300

 atccttgcat ttgctctcgt cacactcaaa gtccttggac ttagaccggg 1350

 gtccctccac tctaactgtt caggcagaac aacggaaaca tccaagttgg 1400

 cctaggttgg atcggaacaa cagcaaggga tatatgaaac tagagaacaa 1450

 agaagacccg atggataggt tgcttgtgcc ccaagttgcc atcaaaaagg 1500

 actttaccaa taaggagaag cttcttatga tttcaagatc tcacaataat 1550

 ttgagttttg aacatgatga gtttttgagt aacaacctaa agaggggaac 1600

 ttctgaaaca aggttttaat gttaaaagaa tatatcattt tacaagggta 1650

 tatattttaa aacgattttc actggtgttt ccttcttaaa gtattggctg 1700

 taagcctttt taatcaaatg gtttgtagtg tattagaatt ggctgcttag 1750

 ttctgtaatg aagatggttg tatgtttggg ttacttgtga ctgcagtact 1800

 ctatgttacc acacatgatt ttatttttct cttcctttga aagcatgatc 1850

 tcttttatta atatgaatgc aaaatgcttg catccaaatt aaagcttatt 1900

 ttctttactt ttaagttctt tgattgccct attcataaaa tgaaatgtcc 1950

 agtatggaaa acatagggta ccaaagtgtg gaccaggagt acaaattcag 2000

 tcccaatact caatacgtat tatagatgac tatgagtgca aaccttagga 2050

 tgtgattttc tgaataattg ttctttgtag gatttggtta cattatttaa 2100

 aatgaaaaag atctagtttt agtgtgagct cagtaatgtt aattggttaa 2150

 gttcattgtg aatcttgagt tttagataag tagttatttt tttcaatatc 2200

 acttctgttt ttagtgatat tatatcaaga aacaacgtat tcaagagcca 2250

 tggctgacag tgccagatat acttagggat aaacatcaaa atgcaattat 2300

 agttgctata acgttagata ctcggaatca aaatttattt gcaagctgac 2350

 ttgataaact aaatgaacca ataaaatttg tagaaatgct atcctgaaat 2400

 aattatatac atgaagacaa tgttgactaa tgaattaaga tacattatat 2450

 actagttaat gctaactagt ctcagtacct gtttttagcc atctgttact 2500

 gtccaatagc acctcattcc cacattctat tttcccccgg tattctttag 2550

 atcctagtat ttggaaaaca atcggctaac cttgacattt ctttttacct 2600

 tcatatgcca ctatctcggt agttcaaaaa aatttaaatt cttgataaat 2650

 tgccttgaag tttaccttgt gctggagagc cttatgataa ctccaaagac 2700

 tttcttacgg tataatacat gttgtttagg attgtgtttc ttagtcactg 2750

 aagataataa atattaaaat ggatgttttc atcagaaaat tttcatgttt 2800

 tcctttaagg taacataatt gtaagaattg tttaataaaa tactcaggaa 2850

 attctaaagg tttctcctaa tacctaaaca tttctgaaca tcagtattgc 2900

 agttgtggaa gagcagaagg aggatacatt tgtttgtgtt gctccccaaa 2950

 attccacctt gcatttgcat cacaaacttc cctcaattga ggcagttttc 3000

 tttgttagaa cattaagtct gtgtattgta atagagtggg ctcaatattt 3050

 tactataaag catttaataa actgttatta atagaaaaaa aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaaaaaa 3120

<210> 4961
<211> 491
<212> PRT
<213> Homo sapien

<400> 4961
 Met Ile Ala Thr Gly Gly Val Ile Thr Gly Leu Ala Ala Leu Lys
   1               5                  10                  15

 Arg Gln Asp Ser Ala Arg Ser Gln Gln His Val Asn Leu Ser Pro
                  20                  25                  30

 Ser Pro Ala Thr Gln Glu Lys Lys Pro Ile Arg Arg Arg Pro Arg
                  35                  40                  45

 Ala Asp Val Val Val Val Arg Gly Lys Ile Arg Leu Tyr Ser Pro
                  50                  55                  60

 Ser Gly Phe Phe Leu Ile Leu Gly Val Leu Ile Ser Ile Ile Gly
                  65                  70                  75

 Ile Ala Met Ala Val Leu Gly Tyr Trp Pro Gln Lys Glu His Phe
                  80                  85                  90

 Ile Asp Ala Glu Thr Thr Leu Ser Thr Asn Glu Thr Gln Val Ile
                  95                 100                 105

 Arg Asn Glu Gly Gly Val Val Val Arg Phe Phe Glu Gln His Leu
                 110                 115                 120

 His Ser Asp Lys Met Lys Met Leu Gly Pro Phe Thr Met Gly Ile
                 125                 130                 135

 Gly Ile Phe Ile Phe Ile Cys Ala Asn Ala Ile Leu His Glu Asn
                 140                 145                 150

 Arg Asp Lys Glu Thr Lys Ile Ile His Met Arg Asp Ile Tyr Ser
                 155                 160                 165

 Thr Val Ile Asp Ile His Thr Leu Arg Ile Lys Glu Gln Arg Gln
                 170                 175                 180

 Met Asn Gly Met Tyr Thr Gly Leu Met Gly Glu Thr Glu Val Lys
                 185                 190                 195

 Gln Asn Gly Ser Ser Cys Ala Ser Arg Leu Ala Ala Asn Thr Ile
                 200                 205                 210

 Ala Ser Phe Ser Gly Phe Arg Ser Ser Phe Arg Met Asp Ser Ser
                 215                 220                 225

 Val Glu Glu Asp Glu Leu Met Leu Asn Glu Gly Lys Ser Ser Gly
                 230                 235                 240

 His Leu Met Pro Pro Leu Leu Ser Asp Ser Ser Val Ser Val Phe
                 245                 250                 255

 Gly Leu Tyr Pro Pro Pro Ser Lys Thr Thr Asp Asp Lys Thr Ser
                 260                 265                 270

 Gly Ser Lys Lys Cys Glu Thr Lys Ser Ile Val Ser Ser Ser Ile
                 275                 280                 285

 Ser Ala Phe Thr Leu Pro Val Ile Lys Leu Asn Asn Cys Val Ile
                 290                 295                 300

 Asp Glu Pro Ser Ile Asp Asn Ile Thr Glu Asp Ala Asp Asn Leu
                 305                 310                 315

 Lys Ser Arg Ser Arg Asn Leu Ser Met Asp Ser Leu Val Val Pro
                 320                 325                 330

 Leu Pro Asn Thr Ser Glu Ser Phe Gln Pro Val Ser Thr Val Leu
                 335                 340                 345

 Pro Arg Asn Asn Ser Ile Gly Glu Ser Leu Ser Ser Gln Tyr Lys
                 350                 355                 360

 Ser Ser Met Ala Leu Gly Pro Gly Ala Gly Gln Leu Leu Ser Pro
                 365                 370                 375

 Gly Ala Ala Arg Arg Gln Phe Gly Ser Asn Thr Ser Leu His Leu
                 380                 385                 390

 Leu Ser Ser His Ser Lys Ser Leu Asp Leu Asp Arg Gly Pro Ser
                 395                 400                 405

 Thr Leu Thr Val Gln Ala Glu Gln Arg Lys His Pro Ser Trp Pro
                 410                 415                 420

 Arg Leu Asp Arg Asn Asn Ser Lys Gly Tyr Met Lys Leu Glu Asn
                 425                 430                 435

 Lys Glu Asp Pro Met Asp Arg Leu Leu Val Pro Gln Val Ala Ile
                 440                 445                 450

 Lys Lys Asp Phe Thr Asn Lys Glu Lys Leu Leu Met Ile Ser Arg
                 455                 460                 465

 Ser His Asn Asn Leu Ser Phe Glu His Asp Glu Phe Leu Ser Asn
                 470                 475                 480

 Asn Leu Lys Arg Gly Thr Ser Glu Thr Arg Phe
                 485                 490

<210> 4962
<211> 1417
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 334-426
<223> Unknown base

<400> 4962
 cttttagtaa tgctattatt gctgcattta aagtaatgtc ttttttcttt 50

 tggctgcttt taatatttac tctttgtgtt tgttttcaac agttaaactt 100

 tgatgtgcat gggtgtggtt ttctttcctg cctttggttc actgagcttc 150

 tttatctttc attagtttta gaaaattcat agccattatc ttttcaaata 200

 ttgctgcttc attctctctc tcttcttcat taacctacgt atagtagaat 250

 ttttgactat gttctgtgtg tctccaacac tgtgttctgt cctttttgcc 300

 cttggtttct gtgctcagtt tggatttgac ctgnnnnnnn nnnnnnnnnn 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnntggt gctgataaat attgatgaat 450

 tctgctctct gctctctatg gttgtcaaca ctgcagagtt gaggcctcat 500

 atctcacctg cactgctgca acagcttact ggtcccttgc tcccagcctt 550

 ctcctcttca gtccatcgtc cacacagcac tggggaaggg gagccacttg 600

 aaacaaaagt caacaactgg ttgtagttca taaacacaga gctgtttgtg 650

 tcccctgtat ctggaatgcc attatgaccc actacatttt ttctttccta 700

 cccctcttaa aactcagttc aggtagcagc tccactagga agccttggct 750

 gaccataatc ccattcaatt ccatttcacc tcttcgcagg cagtctgggg 800

 ttagggaccc tttctctttg ctccccaaaa taaactggtt atctctacta 850

 ttggatttac aacattgtat tataatcttc tccatgtgtg ccttctctag 900

 tagaatgtga gctctttgag gccaaggtct atttaatttg tttgaaaaat 950

 tcattgttat atcctcaaag cctagcacat agtaggtact gaatgaatga 1000

 atgaacaagg ggtgccagga gactgctact cccagtcctt cccagaaact 1050

 gcctagggct ttgagtcatt ttatgaagct aggtcttaat gcgtaggcaa 1100

 cctcccagct cactatgaac gctgacagaa gagtgttttc atgtctataa 1150

 tcaagaattc cagatacatt ccttttactg aaccttgaat tgatcctaag 1200

 attggtagta aaggtattat gttacctcct aacagcacta caaagtacct 1250

 ttttttatca gaaaaaaatt ttaccattag gactcaattt gaagtactaa 1300

 tgcttctcaa gttctccact atgagagtta ccctgtatta gaccgttacc 1350

 tataagaatt aaggggtaaa gcactaaaca gaaaagaaaa aaaaaatagc 1400

 aactctggtg agcagat 1417

<210> 4963
<211> 4061
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3593-3611
<223> Unknown base

<400> 4963
 gggaccctgg tgaccaaagt ggctccggtc agcgcccctc ctaaagtcag 50

 cagcggccct aggctgcctg ctcctcagat agtcgccgtg aaagccccca 100

 acaccacgac aatccagttt cctgctaatt tgcagcttcc tccaggaacc 150

 gttttgatta aaagtaacag tggtccgttg atgttggtat ctcctcagca 200

 aactgtaaca agagccgaga ccacaagtaa cataacctca aggccagcag 250

 taccagcgaa tcctcaaaca gtcaaaatct gtacagtgcc gaactctagc 300

 tcacaattaa tcaagaaagt ggcagtgaca cctgttaaaa aattggcaca 350

 aataggaact actgtggtaa ccactgttcc gaagccttcc tcagtacaat 400

 ctgtggctgt gccaaccagt gtcgtcacag ttactcctgg aaagccattg 450

 aatactgtaa ctaccctgaa gccttcaagt ttgggagcat catccactcc 500

 ttcaaatgag cccaatctta aagcagagaa ctcagcagct gttcagatta 550

 atctttctcc gacaatgcta gaaaatgtga agaaatgcaa gaacttcctt 600

 gcaatgttaa taaaactagc atgtagtgga tcacagtccc ctgaaatggg 650

 gcaaaatgtg aagaagctgg tggaacaact tttggatgca aaaatcgaag 700

 cagaagaatt tactaggaaa ctgtatgttg aactcaagtc ttcacctcag 750

 cctcacctgg ttccttttct taagaaaagc gtggttgcct tacgacaact 800

 tctgcctaac tcccagagct tcatccagca atgtgttcag cagacttcta 850

 gtgacatggt cattgctacc tgtactacaa cagtaacaac ttctcctgtg 900

 gtgacaacta cagtgtcctc aagccagtct gaaaagtcaa ttattgtttc 950

 tggagcaaca gcacccagaa ctgtgtcagt gcaaactttg aacccacttg 1000

 ctggtccagt gggagcaaaa gctggagttg tgacacttca ttctgtgggc 1050

 ccaactgctg caacaggagg aacaacagct ggaactgttt tgcttcagac 1100

 ttcgaaaacc acttgtgaca tctgtaccaa acacagtgac aatggtctca 1150

 ctgcaacctg aaaagccagt tgtccctgga acagaagtaa cactgtccct 1200

 tccagcagta actttgaaga atcttcaggt gcagctattt gtcttccatc 1250

 tgtgaaacct gttgttacat ctgctgggac cacatctgac aagcctgtta 1300

 ttgggactcc agttcaaatc aaacttgccc agccgggccc tgtcctttca 1350

 caaccagctg ggattccaac aggcagttca agtcaagcaa ctagtagttc 1400

 agcagccttc aggaggcaat gaaaaacaag tgaccacaat ttcacattcc 1450

 tcaacattga ccattcagaa atgtggacag aagacgatgc cagtgaacac 1500

 cataatacct actagtcagt ttcctccagc ttccattcta aagcaaatta 1550

 ctctgcctgg aaataaaatt ctgtcacttc aagcatctcc tactcagaaa 1600

 aatagaataa aagagaatgt aacatcatgc ttccgagatg aggatgacat 1650

 caatgatgtg acttctatgg caggggtcaa ccttaatgaa gaaaatgcct 1700

 gcatcttagc aacaaactct gaattggttg gcacactcat tcagtcatgt 1750

 aaagatgaac catttctttt tattggagct ctacaaaaga gaattttaga 1800

 cattggtaaa aagcatgaca ttacagaact taactctgat gctgtgaact 1850

 tgatctccca agcaacacag gaacgactac gaggccttct agaaaaactg 1900

 actgcaattg ctcagcatcg aatgactact tacaaggcaa gtgaaaatta 1950

 catcctgtgt agtgatacca ggtcacagct caaatttctt gaaaagctgg 2000

 atcaattgga gaagcagaga aaggatttgg aagaaagaga aatgttactt 2050

 aaggcagcca agagtcgttc taataaagaa gatccagaac agctgagatt 2100

 aaagcagaaa gccaaagagt tacagcaatt ggaacttgca cagatacagc 2150

 atagagacgc taatctcaca gctcttgcag ctattggacc aaggaagaag 2200

 agaccactag aatctggaat tgagggctta aaagacaacc ttcttgcttc 2250

 tgggacatcc agcctgacag ccaccaaaca gttgcatcgt ccaagaatca 2300

 cgagaatctg cctcagggac ttgatatttt gtatggaaca ggaacgggag 2350

 atgaagtatt ctcgagctct atacctggcc cttctgaagt gaccactcca 2400

 ctcttccatc cagatccttg ctatttactg ccaaagaaga cacaaagcat 2450

 tgttgcactg tcctgaaatt tcaatttctg gaaaataatc accaacatga 2500

 aagagcattg tttacagtta gaaactttat taactcttac ctatccatct 2550

 catgggactc ttacagactc agattcatct ttgtcttctg aaaatcagtt 2600

 atgaaataca ctttgcacag aattaggcat ctgcctatct gtgcattaaa 2650

 ttaaagcaag ttaaggccct atttgttact acctgcctca tttgccaaat 2700

 tgtagcaggt gaggtgtcct tccctaatac agcatgcatt gagatgcagg 2750

 agaaaggaag aggcataaga aaatacaaga atgactattt cattctatat 2800

 tgaacctgtc ccaaagtggt aggttttctg ggctggaatc agaagttgct 2850

 tagctaacta tgacagtcac cctctgtacg tgacaggcca ctgtggtgac 2900

 tttggtcggc tgagttccag tgttgtcaaa acaagacaaa tggggataga 2950

 ttgtgcctgg ggttgctaat tctctgcttc atatcaccat atgccgtttc 3000

 tggtaccaag tgaggggaca tgcttgtcag ggaaacctta aaattgaatc 3050

 tactgatata tcttgttgaa aaaatggaaa aggtgcaaag tattagaagg 3100

 aacgttaggg cgttgctttc aaactgatga ggggaatgtg aaaatggtat 3150

 cataaaacag gaaatgtgct tcatatgccc aagaggggaa gaggtggaat 3200

 cggaactcca aaacaactgg tacatgtttt gttgatgggc aaaaaaaatc 3250

 acagcacaac cagaaaggag aatgtaccag atgttttcaa attagagtat 3300

 ttcaaaagga aaatgttatt ttttgttttg tattgtttta aatcccaagg 3350

 atagttttta tagttccttc tgtcataata tattttagtt atcctaattt 3400

 ttaagcatgt tggcacattt aaaaaatcct aattgatgat gagaaatttt 3450

 taacaatagg actttatgtt ggattctgta cttaaaaggt actgtcaata 3500

 tctcactctt ggggatatga gctctaaata tgagaagcaa gttatatgtg 3550

 ttcacctgag gaagaagctg acggacaaag caaaccctct ttnnnnnnnn 3600

 nnnnnnnnnn nttccacgtg tgtggaatac agccggtgaa aaataatcac 3650

 tgtagttaga atcacataca gaaaaaaaat gattgaatcc tccaagaagg 3700

 tatttcaaaa atgggaaatg ctatacttat aagaattgaa ggaaaaaaaa 3750

 aaaaacacct cacgtatgtt attcttcatc ctgttcttcc cattgggact 3800

 gttatggcca tattctacag tatagtaaat tttaaattgg ccacattttt 3850

 ttttgtttca gcaagttatg taaaatgcta taaattatgt gtatgttaaa 3900

 ggagtacttt aagaagagat ctttatccaa agttgttttt gtatatttaa 3950

 atgcttacct ttattttttt gtaaagtgca gcatactcat ttgtgtataa 4000

 tcttactgat cagatgttta aaattattcc aaatacttca ttaaaataat 4050

 tattttatta t 4061

<210> 4964
<211> 386
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3593-3611
<223> Unknown amino acid

<400> 4964
 Gly Thr Leu Val Thr Lys Val Ala Pro Val Ser Ala Pro Pro Lys
   1               5                  10                  15

 Val Ser Ser Gly Pro Arg Leu Pro Ala Pro Gln Ile Val Ala Val
                  20                  25                  30

 Lys Ala Pro Asn Thr Thr Thr Ile Gln Phe Pro Ala Asn Leu Gln
                  35                  40                  45

 Leu Pro Pro Gly Thr Val Leu Ile Lys Ser Asn Ser Gly Pro Leu
                  50                  55                  60

 Met Leu Val Ser Pro Gln Gln Thr Val Thr Arg Ala Glu Thr Thr
                  65                  70                  75

 Ser Asn Ile Thr Ser Arg Pro Ala Val Pro Ala Asn Pro Gln Thr
                  80                  85                  90

 Val Lys Ile Cys Thr Val Pro Asn Ser Ser Ser Gln Leu Ile Lys
                  95                 100                 105

 Lys Val Ala Val Thr Pro Val Lys Lys Leu Ala Gln Ile Gly Thr
                 110                 115                 120

 Thr Val Val Thr Thr Val Pro Lys Pro Ser Ser Val Gln Ser Val
                 125                 130                 135

 Ala Val Pro Thr Ser Val Val Thr Val Thr Pro Gly Lys Pro Leu
                 140                 145                 150

 Asn Thr Val Thr Thr Leu Lys Pro Ser Ser Leu Gly Ala Ser Ser
                 155                 160                 165

 Thr Pro Ser Asn Glu Pro Asn Leu Lys Ala Glu Asn Ser Ala Ala
                 170                 175                 180

 Val Gln Ile Asn Leu Ser Pro Thr Met Leu Glu Asn Val Lys Lys
                 185                 190                 195

 Cys Lys Asn Phe Leu Ala Met Leu Ile Lys Leu Ala Cys Ser Gly
                 200                 205                 210

 Ser Gln Ser Pro Glu Met Gly Gln Asn Val Lys Lys Leu Val Glu
                 215                 220                 225

 Gln Leu Leu Asp Ala Lys Ile Glu Ala Glu Glu Phe Thr Arg Lys
                 230                 235                 240

 Leu Tyr Val Glu Leu Lys Ser Ser Pro Gln Pro His Leu Val Pro
                 245                 250                 255

 Phe Leu Lys Lys Ser Val Val Ala Leu Arg Gln Leu Leu Pro Asn
                 260                 265                 270

 Ser Gln Ser Phe Ile Gln Gln Cys Val Gln Gln Thr Ser Ser Asp
                 275                 280                 285

 Met Val Ile Ala Thr Cys Thr Thr Thr Val Thr Thr Ser Pro Val
                 290                 295                 300

 Val Thr Thr Thr Val Ser Ser Ser Gln Ser Glu Lys Ser Ile Ile
                 305                 310                 315

 Val Ser Gly Ala Thr Ala Pro Arg Thr Val Ser Val Gln Thr Leu
                 320                 325                 330

 Asn Pro Leu Ala Gly Pro Val Gly Ala Lys Ala Gly Val Val Thr
                 335                 340                 345

 Leu His Ser Val Gly Pro Thr Ala Ala Thr Gly Gly Thr Thr Ala
                 350                 355                 360

 Gly Thr Val Leu Leu Gln Thr Ser Lys Thr Thr Cys Asp Ile Cys
                 365                 370                 375

 Thr Lys His Ser Asp Asn Gly Leu Thr Ala Thr
                 380                 385

<210> 4965
<211> 2791
<212> DNA
<213> Homo sapien

<400> 4965
 atctcatatc atgctttttg cttttaaata tcgccttgag gtttgtctac 50

 actctgccaa aacaatccct gaacataagt ttggtcagcc tcataattca 100

 gtgagtcgag caaccatttg ttccaagtga taaattgtac taaattacaa 150

 actgcccaat cagggcagag ctccatggac ccagcctcca gcccttattt 200

 tataagacta acccctcttc tgaaaaactc tgaaggctta aaagctagca 250

 tttggatgga ggatacttcc tttttatcct tcagctatgt atggcacttt 300

 acataaaata agaggtaaaa aaggagagaa actgatgtgt ataaagtaat 350

 gcctttcttc ccaagcaaat caaacctctc cctatgtaaa agttgatagt 400

 gtaccaagag acacaatacc actggtgggc tggaactagc tcgttctgat 450

 gcataaaagt tgataattaa agtaccagaa attttgtaag ctagttgtta 500

 aacattacca ttattaaata tgaaattata aaacacagtg gaatacatta 550

 aaaaccaatg taataatcaa aacataccac ttcccaatta ttttactacc 600

 ttatactatt tattagtact cttgagtcta tttaggtcta ttacatcttt 650

 acagtgaaaa caggatacaa tattgtgcta ctgtgggtct cttcctgact 700

 gcagattcag taacatggtg ttcgtagctt gaaactgtcc acagtgggag 750

 tatttacacc atagaaactg gctggcaaat gctacaaact agcaatttta 800

 attcctggaa aggcaattgt tgagcattta ccagcacaca atgaatgcca 850

 tattcttttt tttttattag gaaataaatt attggaggca gtataaaatt 900

 atttaaaaag tatcaaatgc aatcccttat cttcagatgg ctataatttt 950

 ggttatataa atgttttggt ttttaccttc tttaaagact cctattaggt 1000

 taaaagtcat atttgatgac tatattttat tcataattaa attattaaat 1050

 caccttttct cctgataatg ctttgccaga gaattcttag caattcaact 1100

 gtagtctaag caataactca gggctaaatt cagggaactg ttagcccaat 1150

 cagatatcac taaaaatgta cttcaccatc tattttggag tttataattt 1200

 tggcatttgc taaaagtagg aaaaacagta acatattact gtgcccagat 1250

 tctaataaat atagctcaat tgaaaccaaa actgttacat taaacaaatt 1300

 acactctggc actatgctaa atcaccacag atgttttagg tgtttgattt 1350

 ccaagcagga tggtatatca tttgtttggt tcaatatatg aggcaccatt 1400

 tgtagtcttt taggaaataa attagctttt atcacagatt taggaaactt 1450

 gtctaaaaaa actgtgatca tcagttacag agggaaggaa acatattgaa 1500

 cacaaggcat catagtagct ggaggcctta aaaattatgc acgaccaaaa 1550

 agaatgattt ggtgagagat gtgtagctga ttgacaattt tagtgtgaat 1600

 tcatattcat ttaacccagc agcaatctac ataagctatg ctttttcccg 1650

 cctgtattta tgtttcttag cttataaagt cccaatatat tatatctttt 1700

 gttgctttgg cagttttaat ttagagctct gcgttcacag agatgccacc 1750

 tatagcaaaa actatcttta agaattggaa aataaaatga atgttttaga 1800

 taaaatattg caagccatta tgtgtagagt taatgtatgg aaatttgcat 1850

 ttgtttttct gaatcatggt gtacattaat cactcattga attctatttc 1900

 taagcaaata agagaatcaa acatttctaa aaggaacata tgtcttgcta 1950

 ttaataacaa ggagacaggt aaaatagtaa ggtaatataa gcaaaaaaaa 2000

 aaatgtaatg aatttagcta tcctaaattg gaatttttac agattgcatg 2050

 catacttaga attttaaatt tttaaaagat ttacaattga gtatggtacc 2100

 cacagagagt gagtaccaag ggaaggaaga cctaatacaa gtgatgttgc 2150

 ctgataaatc acatcttgcc aaaaaaaata tattttagta aatacagttc 2200

 tttaggaaga aaaatgttgc cctttcacac tcacagtgta aatacattca 2250

 taatattcct tcaatcatct aaattaccgc caggtcatga aaggacgcga 2300

 tcaatgatga cctattgcac tcacaggtaa cattgactca aattttggca 2350

 atattgctat attatctaga taattcttgt gatgttttta tgtcactatc 2400

 aacattaaaa atattttgtt aaacaactat gaaactttca aaagtttgca 2450

 tataactgta tgggcactct catttcactg catacataca atactttgta 2500

 tacacatact tctcgtgtgg atattttata attttattta atctaacatt 2550

 taacttttag gtttttgtgg tactcatctg aaaggttggc atttgttttc 2600

 tttttatgtt atatatgtat tttagatgaa tcaataatgt gtattcctag 2650

 aaattttttc taggcataaa tagatcattt tatgttggca tttaagagat 2700

 atcatttttg ttttattgtt ctgtgtaaac catattcatt gtacactgtg 2750

 tgtatatttt tgtttaaata aatgattttt atttttaaaa a 2791

<210> 4966
<211> 6654
<212> DNA
<213> Homo sapien

<400> 4966
 cgcggcgacc cgcgacgaag gagccgggcg tccggggcga gcgggaggca 50

 gccgcactcg ccctggcagc cgcgagctgt gcggcctggg accggccgga 100

 ggtcgccagc gagcagccgc cggctccatt cattcgcgcg gctccgcctc 150

 ctttcccggg ctcttccagc ggctcccggg gcgcgtctga gaggatggca 200

 ttccctgtgg atatgctgga aaattgcagc catgaggaat tggaaaattc 250

 tgctgaagat tacatgtcag atttaaggtg tggggaccct gaaaatccag 300

 agtgtttttc tcttctcaat attacgattc ctattagcct gtcaaatgta 350

 ggctttgtac ctctttatgg tggagatcag acccagaaaa ttcttgctct 400

 ctttgcacct gaagattcac tgacagctgt ggcactttac cttgctgatc 450

 agtggtgggc tattgatgat attgtgaaaa catctgttcc ttcaagagag 500

 gggcttaagc aggtgagcac tcttggggag agagtggttc tgtatgttct 550

 gaatcgaatt atttatagaa aacaggaaat ggagagaaat gagatcccat 600

 tcctgtgtca tagcagtact gattatgcta agattctgtg gaagaaagga 650

 gaggccattg ggttttattc agttaagcct acaggaagca tatgtgcctc 700

 ttttcttacc caaagttacc aattgccagt tcttgataca atgtttctaa 750

 gaaagaaata cagaggtaaa gattttgggc ttcacatgct ggaggacttt 800

 gttgattcct ttacagaaga tgcgcttggc ttgcggtatc cactgtcttc 850

 tctcatgtat acagcttgca agcaatactt tgagaagtat ccaggagacc 900

 atgaactcct ttgggaagtt gaaggtgttg gacactggta ccagcgaata 950

 ccagtcacca gagcattaca aagagaagca cttaaaattc tagcactttc 1000

 tcaaaatgaa cctaaaagac ctatgtctgg agaatatggt cctgcatctg 1050

 ttccagaata cgaagcaaga actgaagaca atcagtctag tgagatgcag 1100

 ctaactattg attctctaaa agatgccttt gcaagcactt ccgaaggtca 1150

 tgataaaaca tctgtttcca ctcatactcg aagtggtaat ctaaagcggc 1200

 caaagattgg aaagcggttt caggattctg aatttagcag ttctcaaggt 1250

 gaagatgaaa agacctccca gacttcactt acagcttcaa taaacaaatt 1300

 ggagtctact gcacgcccat cagagagctc agaagaattc ctggaagaag 1350

 aacctgaaca gagagggatt gaatttgagg atgaaagcag tgatagagat 1400

 gcacggccag cactggaaac ccagccacag caagagaagc aagatggtga 1450

 aaaggaatct gaattagagc ctatgaatgg tgagataatg gacgattctc 1500

 ttaagacctc acttataaca gaagaggaag actccactag tgaagtttta 1550

 gatgaagaat taaaattgca gccttttaat tccagtgaag actctacaaa 1600

 tcttgttcca ctggtggtag aatcttcaaa accccctgag gtagatgcac 1650

 cagataagac cccacgtata cctgactcag aaatgttgat ggatgaaggc 1700

 acatctgatg aaaaggggca catggaagag aaattgtccc tacttccaag 1750

 aaagaaagca catcttggga gttcagacaa tgttgctact atgtcaaatg 1800

 aagaacgatc tgatggtggt tttccaaact ctgtgatagc tgaattttcc 1850

 gaagaaccgg tctctgagaa tttgtctcct aatactactt cctcattgga 1900

 agaccagggt gaggaggggg tatctgagcc ccaggaaaca tctactgctc 1950

 ttcctcagag ttctttgata gaggttgaac ttgaagacgt gccattttca 2000

 cagaatgcag gacagaagaa tcagtcagag gagcagtctg aagcatcttc 2050

 cgagcaactg gatcagttta cacaatcggc agaaaaagct gtggatagca 2100

 gctcagagga aatagaagtg gaagtgcctg tggtagacag gcggaattta 2150

 agaagaaagg ccaaagggca taaaggacct gctaagaaga aagctaagct 2200

 gacctgaagg aagaagaaag tggatgataa atcctcttct ttgtaacata 2250

 gttgttgttt ttaaaatatg gtaattaata aacagcatgg ggcacaggac 2300

 aaaaatttcc aaaatttcaa tttgaactta cttactatgc agttttttgc 2350

 ttccctttag aacgtagaat tcaccattgt ttttaatttt ccaggctatt 2400

 tttggtaaat gcaatttttt atttttatta accatgtttc aattttggga 2450

 aaccagatca tattatattt tctttatcag gtggtacatc tgaccattat 2500

 ttcaaaaata taattaaaaa gctgtgaaag tagtaggatt tccattactt 2550

 ataaggatca cagaaatctt ttatactaag ggttttaata gtaaaacttg 2600

 gtgagggttc tagaagtttt aaatttcaaa actaatcacc aattttttaa 2650

 aatgtaggca tgcctaaaca aaaataagtg tcaataaatt agaaaaaata 2700

 taacttcaag taaatgagag cacaaaaaca gaaacttacg gtcaaaggtt 2750

 catgaagata ttttggtttt ggcctcttaa tcctagatat agatgcagtt 2800

 ttttcctttg acttcactat ctatggaaag gtacacataa aatctgtttc 2850

 tgattcattc tatcatctga tgttaacagt actgtcaggg atttaactgt 2900

 ggcatgtggg gactaattat ttaaaatttc atttgaagta ttagtttgct 2950

 gtaatttttt ttgtctgcat atgtgcagac gcctagaagt ttagactttc 3000

 acctttaatc aggtaaaaat cacaactata ctttggagac atggtttaat 3050

 ttggacttct ggtcctgatc agatagataa attaagctgg agattttact 3100

 tttatcccaa cccagttaac atctatattt cagaagtatg aggctccttc 3150

 ctaaggcatc tccttaaatc ttgccacctc cctaattcta cagtcttatt 3200

 tatattcccc cacagctttc atctacttct gtaactcatg gagtgattct 3250

 ccaatcaaca gatcttcctg cctgccggct tatgcccttg atgtccattt 3300

 ttgggtaggt ttggaggtgc accccacaat gttagaccta tatggcagga 3350

 gtaaaactgc ccccagtgtt agacctatat ggcaggggta aactgccttt 3400

 gggggagctg tggttacaag ggcttcaatc atattggagg cttcaatcat 3450

 cctttgattt gtactgagta ctggttgcaa gctggcctgt taagtatata 3500

 ttgtgttgcc ataacaaagg cctaggaaaa tttgaagaaa aaaaacactg 3550

 aactgttatt ttttgtaatt tatttaaaaa tggacaaaat ggttattaga 3600

 atccaaagat aatctaaaaa cagttctact ctttggaaat attatgtgta 3650

 ctcaaatttg cacttaagtt ggagaatgtt ttgagaccat ttaaattgtt 3700

 ttaaaaatag cttgatcttg atccttatgc aaaagaaact aagactttgt 3750

 gtcattattt gaggtagcta aggactgatg ttgaaagtgt attcagtcta 3800

 tagtaagctg atgtcaggtc agtaaatttt gtttggggat gttggtattt 3850

 tcgatcaagt taaaatctta aagcagacaa aaatagtaaa cgctcctatt 3900

 tgtgttagat tttgaacaat tgtattaccc tatattttct ttaattagtc 3950

 aaaggtaagc cagattattt cattctaaat gaaaattaaa gcactttggc 4000

 catttatttt ttcaacaaat gctaatacta agtaaaaaaa aaaagtatga 4050

 ctactattag tcaatctacc aaacatttat gctgttttat acattttatg 4100

 agaaacttct gtcaatatca caaagggaaa tattctgtta agattcagta 4150

 aattcttaat ctttacatgt ttcatttctt agatttgaaa acacttgtag 4200

 atattttatt tttacttgga tttgtttaaa atactttctt ttcaaattat 4250

 tttaaacatg gaaacgcttc atgaatttgt gtcatccttg cacaggggcc 4300

 atgctaattt tccctgtatt gttctaattt tagtatatgt gctgccgaag 4350

 tgagcactaa aagactttct ttagacaagt gtagtttttt aaagattgag 4400

 ctcactggct caactcttga tgtgtgaata tagttgagtt tacaaaaaat 4450

 gtttattaat catatatgac cattgggggc taacagtata aacttattct 4500

 tgttaaactt gtttgggtta aatagtaagt gaattgtaaa caatttagaa 4550

 gttttttgtt cagcacacaa gaacacttct gttacagatt ctctctgaca 4600

 gaaattgtta ttttggggtt tatagattat agagggaaaa gttagatcac 4650

 ttggaaaaac ctaactctca tgttcagtaa cttgagtata gaatttatac 4700

 cacaatttat cttcaataag gaacctacat gaacttaatc agttatctgt 4750

 agtttttgca aggcattaga aaaaatttca caattacaga ggactgaaaa 4800

 tgtgatttca accggctagt ctagttgttg aatgtccagt cacattacac 4850

 atagtccttt gtgaacttat ttgtgaaggg agttcacttt ttatgtacat 4900

 acgtgtatat ttccttgtgt aatataaagc agatggttat tagtatttta 4950

 gttctttcaa gtttaaatta ttcaattgct agacatcaca gaaattagta 5000

 tatttaagaa tttattataa agctcctcta caacttttaa aggtgagagg 5050

 gtctattatg atttttttat aaaatcaaac agcatgattt agaacgtcag 5100

 tcttctactt aaaatgtgtc tatattcatg gtatttccat tcagtgtaga 5150

 tggtaaggaa aacatctagt cattaaagat ttacttatag cagactccag 5200

 aacactacct acaatggggt ttcagtgact agaaatcttg aaggtttatg 5250

 attgcatcaa attgagcctg tactaatatc taaatatctg ctcttatgtt 5300

 ctgctttatc ccttgggatt accttctaag gtttggtcac accagcaaac 5350

 tgaaacagat cttaatgtac ataaaaaatt tatactaata ttactcatct 5400

 gtgttacagt attttgaaaa atgtttcagg tgtcatctag tcgtctttca 5450

 tgggtgtgat tagttacaaa tgttatgctt atgttttcat acttaatatc 5500

 aagctttctt tgtaccttac aagatagtat ttttggttct aaaaaaaaca 5550

 agcaaacttc atttttgtag tatccagaaa ttacctggag tcagtatttt 5600

 tattcgcctt ctagaacttg tgatccacac atcacccatt tatattagtg 5650

 gtaaaattat ctgctaaaat ctaattgtaa gaaaggctta ccttctgtca 5700

 tcaagtgatt gtatcatcct ggatcgtcat ttccaaggaa ctagcctttc 5750

 ttttcctaag cgtctgtatg tgttctaaaa cttccagtat atatttatag 5800

 aacttagaaa aaatgttaca ttattcagag tagcaagtct tactggagta 5850

 cctatgtttg ttttcttggt ttttattttt ttttaagttt aaaagtagta 5900

 attaaaccta tattttgtga ttgtttcctg gtctgtgttt ttaaattcct 5950

 ttccttcagt tttcctcatg aagatgtttc agatactgaa tttgtttaga 6000

 cattgaatga ctttgttaaa ggcacaatta atcacattgg ttgtactctg 6050

 aagacagact tctttaaaaa aaaaataaac aatttaaaac aatgtggtga 6100

 ttatagatta atgtaatata cgccatcctt aaaaccacaa catataacag 6150

 atcacaaaag tgctttcacc aagttacaac cgtaaatcct taccttttta 6200

 catcatctaa gtaactgcaa ataaatttct cctcagggaa tcagtgcagt 6250

 cttctttttc cttttaaaac ttagctggag ttacttaaac taattcttaa 6300

 tactattctg aaagtataaa tatattgttt agaatacaga aaatgctaag 6350

 agagtacaaa gactttagta tatttttttc attttcatga ttcaagtaga 6400

 aaatagtgcc aagtaggtat tattatacat ggtaaatgag atgaaaaaaa 6450

 tgtttagaat gtgaattcac tagacctttg ctgtactgga tttcacaggt 6500

 gaaaagattt ctctaagatt tctgaacttt tagtgtcttc tcacatactt 6550

 ctagtgtaaa caaacactat aaacttaaca tctgtattaa tgctacctac 6600

 cttttttagg attaatgatt aacgagattt tgaagatact tcagttaaat 6650

 tctc 6654

<210> 4967
<211> 734
<212> PRT
<213> Homo sapien

<400> 4967
 Arg Arg Pro Ala Thr Lys Glu Pro Gly Val Arg Gly Glu Arg Glu
   1               5                  10                  15

 Ala Ala Ala Leu Ala Leu Ala Ala Ala Ser Cys Ala Ala Trp Asp
                  20                  25                  30

 Arg Pro Glu Val Ala Ser Glu Gln Pro Pro Ala Pro Phe Ile Arg
                  35                  40                  45

 Ala Ala Pro Pro Pro Phe Pro Gly Ser Ser Ser Gly Ser Arg Gly
                  50                  55                  60

 Ala Ser Glu Arg Met Ala Phe Pro Val Asp Met Leu Glu Asn Cys
                  65                  70                  75

 Ser His Glu Glu Leu Glu Asn Ser Ala Glu Asp Tyr Met Ser Asp
                  80                  85                  90

 Leu Arg Cys Gly Asp Pro Glu Asn Pro Glu Cys Phe Ser Leu Leu
                  95                 100                 105

 Asn Ile Thr Ile Pro Ile Ser Leu Ser Asn Val Gly Phe Val Pro
                 110                 115                 120

 Leu Tyr Gly Gly Asp Gln Thr Gln Lys Ile Leu Ala Leu Phe Ala
                 125                 130                 135

 Pro Glu Asp Ser Leu Thr Ala Val Ala Leu Tyr Leu Ala Asp Gln
                 140                 145                 150

 Trp Trp Ala Ile Asp Asp Ile Val Lys Thr Ser Val Pro Ser Arg
                 155                 160                 165

 Glu Gly Leu Lys Gln Val Ser Thr Leu Gly Glu Arg Val Val Leu
                 170                 175                 180

 Tyr Val Leu Asn Arg Ile Ile Tyr Arg Lys Gln Glu Met Glu Arg
                 185                 190                 195

 Asn Glu Ile Pro Phe Leu Cys His Ser Ser Thr Asp Tyr Ala Lys
                 200                 205                 210

 Ile Leu Trp Lys Lys Gly Glu Ala Ile Gly Phe Tyr Ser Val Lys
                 215                 220                 225

 Pro Thr Gly Ser Ile Cys Ala Ser Phe Leu Thr Gln Ser Tyr Gln
                 230                 235                 240

 Leu Pro Val Leu Asp Thr Met Phe Leu Arg Lys Lys Tyr Arg Gly
                 245                 250                 255

 Lys Asp Phe Gly Leu His Met Leu Glu Asp Phe Val Asp Ser Phe
                 260                 265                 270

 Thr Glu Asp Ala Leu Gly Leu Arg Tyr Pro Leu Ser Ser Leu Met
                 275                 280                 285

 Tyr Thr Ala Cys Lys Gln Tyr Phe Glu Lys Tyr Pro Gly Asp His
                 290                 295                 300

 Glu Leu Leu Trp Glu Val Glu Gly Val Gly His Trp Tyr Gln Arg
                 305                 310                 315

 Ile Pro Val Thr Arg Ala Leu Gln Arg Glu Ala Leu Lys Ile Leu
                 320                 325                 330

 Ala Leu Ser Gln Asn Glu Pro Lys Arg Pro Met Ser Gly Glu Tyr
                 335                 340                 345

 Gly Pro Ala Ser Val Pro Glu Tyr Glu Ala Arg Thr Glu Asp Asn
                 350                 355                 360

 Gln Ser Ser Glu Met Gln Leu Thr Ile Asp Ser Leu Lys Asp Ala
                 365                 370                 375

 Phe Ala Ser Thr Ser Glu Gly His Asp Lys Thr Ser Val Ser Thr
                 380                 385                 390

 His Thr Arg Ser Gly Asn Leu Lys Arg Pro Lys Ile Gly Lys Arg
                 395                 400                 405

 Phe Gln Asp Ser Glu Phe Ser Ser Ser Gln Gly Glu Asp Glu Lys
                 410                 415                 420

 Thr Ser Gln Thr Ser Leu Thr Ala Ser Ile Asn Lys Leu Glu Ser
                 425                 430                 435

 Thr Ala Arg Pro Ser Glu Ser Ser Glu Glu Phe Leu Glu Glu Glu
                 440                 445                 450

 Pro Glu Gln Arg Gly Ile Glu Phe Glu Asp Glu Ser Ser Asp Arg
                 455                 460                 465

 Asp Ala Arg Pro Ala Leu Glu Thr Gln Pro Gln Gln Glu Lys Gln
                 470                 475                 480

 Asp Gly Glu Lys Glu Ser Glu Leu Glu Pro Met Asn Gly Glu Ile
                 485                 490                 495

 Met Asp Asp Ser Leu Lys Thr Ser Leu Ile Thr Glu Glu Glu Asp
                 500                 505                 510

 Ser Thr Ser Glu Val Leu Asp Glu Glu Leu Lys Leu Gln Pro Phe
                 515                 520                 525

 Asn Ser Ser Glu Asp Ser Thr Asn Leu Val Pro Leu Val Val Glu
                 530                 535                 540

 Ser Ser Lys Pro Pro Glu Val Asp Ala Pro Asp Lys Thr Pro Arg
                 545                 550                 555

 Ile Pro Asp Ser Glu Met Leu Met Asp Glu Gly Thr Ser Asp Glu
                 560                 565                 570

 Lys Gly His Met Glu Glu Lys Leu Ser Leu Leu Pro Arg Lys Lys
                 575                 580                 585

 Ala His Leu Gly Ser Ser Asp Asn Val Ala Thr Met Ser Asn Glu
                 590                 595                 600

 Glu Arg Ser Asp Gly Gly Phe Pro Asn Ser Val Ile Ala Glu Phe
                 605                 610                 615

 Ser Glu Glu Pro Val Ser Glu Asn Leu Ser Pro Asn Thr Thr Ser
                 620                 625                 630

 Ser Leu Glu Asp Gln Gly Glu Glu Gly Val Ser Glu Pro Gln Glu
                 635                 640                 645

 Thr Ser Thr Ala Leu Pro Gln Ser Ser Leu Ile Glu Val Glu Leu
                 650                 655                 660

 Glu Asp Val Pro Phe Ser Gln Asn Ala Gly Gln Lys Asn Gln Ser
                 665                 670                 675

 Glu Glu Gln Ser Glu Ala Ser Ser Glu Gln Leu Asp Gln Phe Thr
                 680                 685                 690

 Gln Ser Ala Glu Lys Ala Val Asp Ser Ser Ser Glu Glu Ile Glu
                 695                 700                 705

 Val Glu Val Pro Val Val Asp Arg Arg Asn Leu Arg Arg Lys Ala
                 710                 715                 720

 Lys Gly His Lys Gly Pro Ala Lys Lys Lys Ala Lys Leu Thr
                 725                 730

<210> 4968
<211> 4564
<212> DNA
<213> Homo sapien

<400> 4968
 catctggaaa cccgggtcct gcaagaactg cttctgcctg cggagcgacc 50

 accagctggt ggccggccct ccccagccca gagcgggcag cctgccccct 100

 ccaccgcgcc tgcctcccag gcctgagaac tgccgcctgg aagatgaagg 150

 tgtgaacagc tcaccttact ccaagcccac aattgccgtg aagcccacca 200

 tgatgagctc cgaggcctct gatgtgtgga cagaggccaa cctgagtgcc 250

 gaagtctcgc aggtcatctg gagacgagcc cctggcaagc tccccctccc 300

 gaagcaggag gatgcccccg tcgtctacct gggcagcttc cgaggtgtac 350

 agaagcctgc tggtccctct acctcccctg atggcaattc tcgctgtccc 400

 ccagcttaca ccatggtcgg cctgcacaac cttgagcccc gcggcgagag 450

 gaacattgcc ttccacccgg tgagcttccc ggaggagaag gctgtgcaca 500

 aagaaaaacc ctcatttcct taccaagacc ggccctccac ccaggagagc 550

 ttccgccaga aactggctgc ctttgctggg accacatctg gctgtcacca 600

 gggccctggg cccctgcggg aatccctgcc ctcggaggat gacagtgatc 650

 aaaggtgctc gccctccggg gacagcgagg gtggagagta ctgctccatc 700

 ctggactgct gccctgggag ccctgttgcc aaggctgcct cccagactgc 750

 aggttcccgg ggcaggcatg gtggcaggga ctgctcaccc acgtgctggg 800

 agcaggggaa gtgttccggg cccgcagagc aggagaagcg gggcccgagc 850

 ttccccaagg agtgctgtag ccagggcccc actgcccacc catcctgcct 900

 gggccccaag aaactgtccc tcacctcgga ggctgccatt tcttccgacg 950

 gcctctcttg tggcagcggc agcggcagcg gcagcggcgc cagtagcccc 1000

 ttcgtccccc acctcgagag tgattactgc tccctcatga aggaacctgc 1050

 cccagagaag cagcaggacc ctggctgccc aggggtgacc cctagcagat 1100

 gccttgggct gacgggggag ccccagcccc cggcccaccc ccaggaggct 1150

 acacagcctg aacccatcta tgctgagagc accaagagga agaaggcagc 1200

 tccggtgcct tccaagtcac aggccaagat agaacatgca gctgctgccc 1250

 agggccaagg ccaggtatgc acaggtaatg cctgggccca gaaagcagca 1300

 tctggctggg gccgggacag cccagaccca actccccagg tgtcagccac 1350

 catcacagtc atggcggccc acccggaaga ggaccatcgg acgatctacc 1400

 tgagcagccc tgactctgca gtgggggtgc agtggccacg agggcctgtg 1450

 agccagaact ccgaggtagg tgaagaggag acttcggctg ggcaggggct 1500

 gagctccagg gaaagccatg ctcacagtgc cagcgagagc aagcccaagg 1550

 agaggcccgc cattcccccc aagttgtcca agagtagccc tgtagggtcc 1600

 ccggtgtcac cgtctgctgg agggccccca gtgtcactac tggctgacct 1650

 tagtgatggg agctgtggcg gcagcagcat tgggccccag cctccatccc 1700

 aaggtcctgc tgaccccgct ccttcctgcc ggaccaacgg tgtcgctatc 1750

 agtgacccat ccaggtgtcc ccagcctgcg gcctcgtcag cctcggaaca 1800

 gaggcggccc aggttccagg caggcacctg gagtcgtcag tgccggatag 1850

 aggaagaaga ggaggtggag caggaattgc tgagtcacag ctggggaaga 1900

 gagaccaaaa atggccccac ggaccattca aactccacga cctggcaccg 1950

 tctccacccc acagatggct cctctgggca gaacagcaaa gttgggaccg 2000

 ggatgagcaa atccgcctct tttgcctttg agttccccaa ggacagaagt 2050

 gggattgaga cattctcacc tcctcctccg cctccaaagt cgcggcacct 2100

 tctaaaaatg aacaagagca gctctgattt ggaaaaagtg agccagggct 2150

 ctgcagaaag cctcagccca tccttcaggg gtgtccacgt cagcttcacc 2200

 accggctcca cggacagcct ggcctcagac tctaggacct gcagcgatgg 2250

 aggtccctcg tctgagctgg ctcactcgcc caccaacagc gggaagaagc 2300

 tctttgctcc cgttccgttt ccttcaggct ccactgagga cgtgtccccc 2350

 agtggccccc agcagccccc tccactcccc cagaaaaaga tagtgagccg 2400

 ggcagcctct tcaccggatg gcttcttctg gacccaaggc tcccccaagc 2450

 ccggaacagc aagccccaag ctgaacctaa gccactcgga aaccaacgtc 2500

 cacgacgaat ctcactttag ctattcgttg agccccggga accgccacca 2550

 tcctgtcttc tcctcttccg atcctctgga gaaagctttc aaaggcagtg 2600

 gccactggct tccggcagca gggctggcgg gcaacagagg cggctgcggg 2650

 agccctggcc tccagtgcaa aggggccccc tccgcctcat cctcccagct 2700

 gagcgtgtcc agtcaagcct ccaccgggag cacccagctt cagctgcacg 2750

 gtctcctgag caacatcagc agcaaggagg gcacctatgc caagctgggg 2800

 ggactctaca cccagtccct ggcccgcctt gtagccaaat gtgaggacct 2850

 cttcatgggc ggccagaaaa aggagctcca cttcaatgag aataactggt 2900

 cgctcttcaa gctgacttgt aacaagccct gctgtgactc gggggatgcc 2950

 atttattact gtgccacctg ctctgaggac cccggcagca cctatgctgt 3000

 gaaaatctgc aaagcccctg agcccaaaac agtctcctac tgcagcccgt 3050

 ccgtgcccgt gcactttaac atccagcagg actgcggcca cttcgtcgcc 3100

 tcggtgccgt ccagcatgct cagctccccc gacgcgccca aggaccctgt 3150

 gcctgccctg cccacacacc cccctgccca ggagcaggac tgcgtggtgg 3200

 tcatcacccg agaggtgcca catcagaccg cctccgactt cgtgcgggac 3250

 tcggcggcca gccaccagac ggagcccgag gcgtacgagc ggcgcgtgtg 3300

 cttcctgctt ctgcaactct gcaacgggct ggagcacctg aaggagcacg 3350

 ggatcatcca ccgggacctg tgcctggaga acctgctgct ggtgcactgc 3400

 accctccagg ccggccccgg gcccgccccc gcccccgccc cggctcccgc 3450

 ccccgccgcc gccgcgcctc cctgctcctc tgccgccccg cctgctggtg 3500

 gcactctcag ccccgcagcc ggccccgcct ccccggaagg gccccgggag 3550

 aagcagctgc cccggctcat catcagcaac tttttgaagg ccaagcagaa 3600

 gccgggcagc accccaaacc tgcagcagaa gaagagccag gcccggctgg 3650

 cccccgagat cgtgtctgct tcccagtacc gcaagttcga tgagttccag 3700

 acaggcatcc tcatctacga gctgctgcac caacccaacc cgttcgaggt 3750

 gcgcgcccag ctgcgggaga gagactaccg gcaggaggac ctgccgccgc 3800

 tgcccgcgct gtccctctac tcacccggcc tgcagcagct ggcacatctg 3850

 ctactggagg ccgaccccat caagcgtatc cgcatcggcg aggccaagcg 3900

 cgtgctgcag tgcctgctgt gggggcctcg gcgcgagctg gtgcagcagc 3950

 cgggcacctc ggaggaggcg ctgtgcggca cgctgcacaa ctggatcgac 4000

 atgaagcggg ccctgatgat gatgaagttt gcggagaagg cggtggatcg 4050

 caggcggggc gtggagctgg aggactggct ttgctgccag tacctggcgt 4100

 ctgcggagcc cggggccctc ttacagtcgc tgaagctcct gcagcttctg 4150

 tgagccaagc cccagcctgc accgtcgctg ccccttccct gcctaaccct 4200

 ttcctgtctc gccttggaag cacccatgtc tcccctggga aatggtacag 4250

 atgactggga tacctggatg taaaatatat aaatatatat atagaaaata 4300

 catataccat atataaatat gaaagactaa ggatgctgtt gcccgtccac 4350

 actcgtctcc tctctgcact aagtcctccc tgttttcttc tgtaattata 4400

 cacatttcca gttccatgca acgtcctgag gacagttctg tgaactgaat 4450

 gcagcctgga cactggcctc aataccttgt ttaggatttc ttcacccttt 4500

 tgtcaaattg ttatttaaag aaaaaaaaaa aagaagaaaa ttccattaaa 4550

 attttttttg gttg 4564

<210> 4969
<211> 1383
<212> PRT
<213> Homo sapien

<400> 4969
 Ile Trp Lys Pro Gly Ser Cys Lys Asn Cys Phe Cys Leu Arg Ser
   1               5                  10                  15

 Asp His Gln Leu Val Ala Gly Pro Pro Gln Pro Arg Ala Gly Ser
                  20                  25                  30

 Leu Pro Pro Pro Pro Arg Leu Pro Pro Arg Pro Glu Asn Cys Arg
                  35                  40                  45

 Leu Glu Asp Glu Gly Val Asn Ser Ser Pro Tyr Ser Lys Pro Thr
                  50                  55                  60

 Ile Ala Val Lys Pro Thr Met Met Ser Ser Glu Ala Ser Asp Val
                  65                  70                  75

 Trp Thr Glu Ala Asn Leu Ser Ala Glu Val Ser Gln Val Ile Trp
                  80                  85                  90

 Arg Arg Ala Pro Gly Lys Leu Pro Leu Pro Lys Gln Glu Asp Ala
                  95                 100                 105

 Pro Val Val Tyr Leu Gly Ser Phe Arg Gly Val Gln Lys Pro Ala
                 110                 115                 120

 Gly Pro Ser Thr Ser Pro Asp Gly Asn Ser Arg Cys Pro Pro Ala
                 125                 130                 135

 Tyr Thr Met Val Gly Leu His Asn Leu Glu Pro Arg Gly Glu Arg
                 140                 145                 150

 Asn Ile Ala Phe His Pro Val Ser Phe Pro Glu Glu Lys Ala Val
                 155                 160                 165

 His Lys Glu Lys Pro Ser Phe Pro Tyr Gln Asp Arg Pro Ser Thr
                 170                 175                 180

 Gln Glu Ser Phe Arg Gln Lys Leu Ala Ala Phe Ala Gly Thr Thr
                 185                 190                 195

 Ser Gly Cys His Gln Gly Pro Gly Pro Leu Arg Glu Ser Leu Pro
                 200                 205                 210

 Ser Glu Asp Asp Ser Asp Gln Arg Cys Ser Pro Ser Gly Asp Ser
                 215                 220                 225

 Glu Gly Gly Glu Tyr Cys Ser Ile Leu Asp Cys Cys Pro Gly Ser
                 230                 235                 240

 Pro Val Ala Lys Ala Ala Ser Gln Thr Ala Gly Ser Arg Gly Arg
                 245                 250                 255

 His Gly Gly Arg Asp Cys Ser Pro Thr Cys Trp Glu Gln Gly Lys
                 260                 265                 270

 Cys Ser Gly Pro Ala Glu Gln Glu Lys Arg Gly Pro Ser Phe Pro
                 275                 280                 285

 Lys Glu Cys Cys Ser Gln Gly Pro Thr Ala His Pro Ser Cys Leu
                 290                 295                 300

 Gly Pro Lys Lys Leu Ser Leu Thr Ser Glu Ala Ala Ile Ser Ser
                 305                 310                 315

 Asp Gly Leu Ser Cys Gly Ser Gly Ser Gly Ser Gly Ser Gly Ala
                 320                 325                 330

 Ser Ser Pro Phe Val Pro His Leu Glu Ser Asp Tyr Cys Ser Leu
                 335                 340                 345

 Met Lys Glu Pro Ala Pro Glu Lys Gln Gln Asp Pro Gly Cys Pro
                 350                 355                 360

 Gly Val Thr Pro Ser Arg Cys Leu Gly Leu Thr Gly Glu Pro Gln
                 365                 370                 375

 Pro Pro Ala His Pro Gln Glu Ala Thr Gln Pro Glu Pro Ile Tyr
                 380                 385                 390

 Ala Glu Ser Thr Lys Arg Lys Lys Ala Ala Pro Val Pro Ser Lys
                 395                 400                 405

 Ser Gln Ala Lys Ile Glu His Ala Ala Ala Ala Gln Gly Gln Gly
                 410                 415                 420

 Gln Val Cys Thr Gly Asn Ala Trp Ala Gln Lys Ala Ala Ser Gly
                 425                 430                 435

 Trp Gly Arg Asp Ser Pro Asp Pro Thr Pro Gln Val Ser Ala Thr
                 440                 445                 450

 Ile Thr Val Met Ala Ala His Pro Glu Glu Asp His Arg Thr Ile
                 455                 460                 465

 Tyr Leu Ser Ser Pro Asp Ser Ala Val Gly Val Gln Trp Pro Arg
                 470                 475                 480

 Gly Pro Val Ser Gln Asn Ser Glu Val Gly Glu Glu Glu Thr Ser
                 485                 490                 495

 Ala Gly Gln Gly Leu Ser Ser Arg Glu Ser His Ala His Ser Ala
                 500                 505                 510

 Ser Glu Ser Lys Pro Lys Glu Arg Pro Ala Ile Pro Pro Lys Leu
                 515                 520                 525

 Ser Lys Ser Ser Pro Val Gly Ser Pro Val Ser Pro Ser Ala Gly
                 530                 535                 540

 Gly Pro Pro Val Ser Leu Leu Ala Asp Leu Ser Asp Gly Ser Cys
                 545                 550                 555

 Gly Gly Ser Ser Ile Gly Pro Gln Pro Pro Ser Gln Gly Pro Ala
                 560                 565                 570

 Asp Pro Ala Pro Ser Cys Arg Thr Asn Gly Val Ala Ile Ser Asp
                 575                 580                 585

 Pro Ser Arg Cys Pro Gln Pro Ala Ala Ser Ser Ala Ser Glu Gln
                 590                 595                 600

 Arg Arg Pro Arg Phe Gln Ala Gly Thr Trp Ser Arg Gln Cys Arg
                 605                 610                 615

 Ile Glu Glu Glu Glu Glu Val Glu Gln Glu Leu Leu Ser His Ser
                 620                 625                 630

 Trp Gly Arg Glu Thr Lys Asn Gly Pro Thr Asp His Ser Asn Ser
                 635                 640                 645

 Thr Thr Trp His Arg Leu His Pro Thr Asp Gly Ser Ser Gly Gln
                 650                 655                 660

 Asn Ser Lys Val Gly Thr Gly Met Ser Lys Ser Ala Ser Phe Ala
                 665                 670                 675

 Phe Glu Phe Pro Lys Asp Arg Ser Gly Ile Glu Thr Phe Ser Pro
                 680                 685                 690

 Pro Pro Pro Pro Pro Lys Ser Arg His Leu Leu Lys Met Asn Lys
                 695                 700                 705

 Ser Ser Ser Asp Leu Glu Lys Val Ser Gln Gly Ser Ala Glu Ser
                 710                 715                 720

 Leu Ser Pro Ser Phe Arg Gly Val His Val Ser Phe Thr Thr Gly
                 725                 730                 735

 Ser Thr Asp Ser Leu Ala Ser Asp Ser Arg Thr Cys Ser Asp Gly
                 740                 745                 750

 Gly Pro Ser Ser Glu Leu Ala His Ser Pro Thr Asn Ser Gly Lys
                 755                 760                 765

 Lys Leu Phe Ala Pro Val Pro Phe Pro Ser Gly Ser Thr Glu Asp
                 770                 775                 780

 Val Ser Pro Ser Gly Pro Gln Gln Pro Pro Pro Leu Pro Gln Lys
                 785                 790                 795

 Lys Ile Val Ser Arg Ala Ala Ser Ser Pro Asp Gly Phe Phe Trp
                 800                 805                 810

 Thr Gln Gly Ser Pro Lys Pro Gly Thr Ala Ser Pro Lys Leu Asn
                 815                 820                 825

 Leu Ser His Ser Glu Thr Asn Val His Asp Glu Ser His Phe Ser
                 830                 835                 840

 Tyr Ser Leu Ser Pro Gly Asn Arg His His Pro Val Phe Ser Ser
                 845                 850                 855

 Ser Asp Pro Leu Glu Lys Ala Phe Lys Gly Ser Gly His Trp Leu
                 860                 865                 870

 Pro Ala Ala Gly Leu Ala Gly Asn Arg Gly Gly Cys Gly Ser Pro
                 875                 880                 885

 Gly Leu Gln Cys Lys Gly Ala Pro Ser Ala Ser Ser Ser Gln Leu
                 890                 895                 900

 Ser Val Ser Ser Gln Ala Ser Thr Gly Ser Thr Gln Leu Gln Leu
                 905                 910                 915

 His Gly Leu Leu Ser Asn Ile Ser Ser Lys Glu Gly Thr Tyr Ala
                 920                 925                 930

 Lys Leu Gly Gly Leu Tyr Thr Gln Ser Leu Ala Arg Leu Val Ala
                 935                 940                 945

 Lys Cys Glu Asp Leu Phe Met Gly Gly Gln Lys Lys Glu Leu His
                 950                 955                 960

 Phe Asn Glu Asn Asn Trp Ser Leu Phe Lys Leu Thr Cys Asn Lys
                 965                 970                 975

 Pro Cys Cys Asp Ser Gly Asp Ala Ile Tyr Tyr Cys Ala Thr Cys
                 980                 985                 990

 Ser Glu Asp Pro Gly Ser Thr Tyr Ala Val Lys Ile Cys Lys Ala
                 995                1000                1005

 Pro Glu Pro Lys Thr Val Ser Tyr Cys Ser Pro Ser Val Pro Val
                1010                1015                1020

 His Phe Asn Ile Gln Gln Asp Cys Gly His Phe Val Ala Ser Val
                1025                1030                1035

 Pro Ser Ser Met Leu Ser Ser Pro Asp Ala Pro Lys Asp Pro Val
                1040                1045                1050

 Pro Ala Leu Pro Thr His Pro Pro Ala Gln Glu Gln Asp Cys Val
                1055                1060                1065

 Val Val Ile Thr Arg Glu Val Pro His Gln Thr Ala Ser Asp Phe
                1070                1075                1080

 Val Arg Asp Ser Ala Ala Ser His Gln Thr Glu Pro Glu Ala Tyr
                1085                1090                1095

 Glu Arg Arg Val Cys Phe Leu Leu Leu Gln Leu Cys Asn Gly Leu
                1100                1105                1110

 Glu His Leu Lys Glu His Gly Ile Ile His Arg Asp Leu Cys Leu
                1115                1120                1125

 Glu Asn Leu Leu Leu Val His Cys Thr Leu Gln Ala Gly Pro Gly
                1130                1135                1140

 Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Ala Ala Ala
                1145                1150                1155

 Pro Pro Cys Ser Ser Ala Ala Pro Pro Ala Gly Gly Thr Leu Ser
                1160                1165                1170

 Pro Ala Ala Gly Pro Ala Ser Pro Glu Gly Pro Arg Glu Lys Gln
                1175                1180                1185

 Leu Pro Arg Leu Ile Ile Ser Asn Phe Leu Lys Ala Lys Gln Lys
                1190                1195                1200

 Pro Gly Ser Thr Pro Asn Leu Gln Gln Lys Lys Ser Gln Ala Arg
                1205                1210                1215

 Leu Ala Pro Glu Ile Val Ser Ala Ser Gln Tyr Arg Lys Phe Asp
                1220                1225                1230

 Glu Phe Gln Thr Gly Ile Leu Ile Tyr Glu Leu Leu His Gln Pro
                1235                1240                1245

 Asn Pro Phe Glu Val Arg Ala Gln Leu Arg Glu Arg Asp Tyr Arg
                1250                1255                1260

 Gln Glu Asp Leu Pro Pro Leu Pro Ala Leu Ser Leu Tyr Ser Pro
                1265                1270                1275

 Gly Leu Gln Gln Leu Ala His Leu Leu Leu Glu Ala Asp Pro Ile
                1280                1285                1290

 Lys Arg Ile Arg Ile Gly Glu Ala Lys Arg Val Leu Gln Cys Leu
                1295                1300                1305

 Leu Trp Gly Pro Arg Arg Glu Leu Val Gln Gln Pro Gly Thr Ser
                1310                1315                1320

 Glu Glu Ala Leu Cys Gly Thr Leu His Asn Trp Ile Asp Met Lys
                1325                1330                1335

 Arg Ala Leu Met Met Met Lys Phe Ala Glu Lys Ala Val Asp Arg
                1340                1345                1350

 Arg Arg Gly Val Glu Leu Glu Asp Trp Leu Cys Cys Gln Tyr Leu
                1355                1360                1365

 Ala Ser Ala Glu Pro Gly Ala Leu Leu Gln Ser Leu Lys Leu Leu
                1370                1375                1380

 Gln Leu Leu


<210> 4970
<211> 1792
<212> DNA
<213> Homo sapien

<400> 4970
 gaaaaagaaa agaaaagaaa aggtacatca gacatgactg cctgcatgaa 50

 gtcaaacagg gtaacaccag tgaagctcaa gtcaagagct gtggatattt 100

 tgtctaacca acaagaagtc tcaagaaatc aggcagtgca gctgcctgct 150

 ctcagctatc gtatccagcc aaaagatgca tgatgatgga gtggtggggg 200

 aaggccagtt cagtatccta tttaaaagta aacttcctga ataatggata 250

 tatgtggaga tacagacata gatatataga tacagctgta attatttagc 300

 ctcaagtgac tttctccatt gcttcacgct atgccactat tttgcttctt 350

 taattttttt aaccttgctt agtattctat agtttgccca accagtttta 400

 cgtccaagga aaattagcca atgcataaaa tatacaaact atgaaaggca 450

 aggatcagga aaccagagac tttgccacca aatctcagat tattagaaac 500

 taggtgtcag ggtttatcaa gaaggccagg aaggcctttt gggttaagcc 550

 ttacattcat gaagaacctc gagggtagat ttttgagagc attccaaatg 600

 aatggtctct ggtcaaatga atgaatggtc aaatgaataa atctgccctc 650

 acagagatac aaaaggaaaa ggaatataat tcataccatt tggtttaagc 700

 cttacattca tgaagaacct caagggtaga tttttgagat cattccaaat 750

 gaagtcgaat ctgccctcac agagacacaa gaaaggaata taattcatac 800

 actattgcat ttttaataaa tcttttgaaa tttgcagaat tagattgtat 850

 tgtgtatttt cggttaaatg ataattgaat gtaaatattt agatgcagca 900

 ccatatttta taacccagct ttagcatttc ttcatatttt aaggaaaccc 950

 cccacctcct tcttttaagg gcgcttcttg ctctctgaaa tgccctgcta 1000

 aatgcttctc ttaattattt gaataaggta gtttggaata aagaaagaaa 1050

 agatcactct acatacagat agtaaactta atttgtgatc ctatatatga 1100

 gacagtataa aaatacagat aagttttaga aagactcaaa acaatatgta 1150

 aatgactgat gtttgcatta ttaaggaaaa cttgggatgt tgggtcaaga 1200

 ggggaaagtg ttagtcaatc cactttggag caatatcatg aaggtcaatt 1250

 ataattccat atacctttct ttgatgccac agtcagagat agaatacagt 1300

 ttgggtggcc atggatgtgc cccaatacag tacacatttt ttggttaaat 1350

 ttgttttcag atcatttcat ggaatctttg aagtatcttt gactctaact 1400

 ttgacttggt ggtggacctt ccttggtttt tataacacct aagagatatc 1450

 ctttagaatt acatgtattt tagcataagg aaattgaaaa agtaaaacat 1500

 actggttttt ttcaacaaga ccatatgtaa attaaatagt gaaatgtgta 1550

 tgagtttcag tagaactgta ccatcaacaa tgtttccata aatatgcaga 1600

 gttctttctt ttgtattgtt atttacaata ttgttaaatt gaatgcattt 1650

 gcaatttcta ggattctaaa gaattgagta cagaaagtag caattttatt 1700

 atttgatgat aatatgagaa ttactgtgcc aatactgttt tgataaataa 1750

 atagattttt aaaaataaat gtattgtact tattagtgta gt 1792

<210> 4971
<211> 60
<212> PRT
<213> Homo sapien

<400> 4971
 Glu Lys Glu Lys Lys Arg Lys Gly Thr Ser Asp Met Thr Ala Cys
   1               5                  10                  15

 Met Lys Ser Asn Arg Val Thr Pro Val Lys Leu Lys Ser Arg Ala
                  20                  25                  30

 Val Asp Ile Leu Ser Asn Gln Gln Glu Val Ser Arg Asn Gln Ala
                  35                  40                  45

 Val Gln Leu Pro Ala Leu Ser Tyr Arg Ile Gln Pro Lys Asp Ala
                  50                  55                  60

<210> 4972
<211> 1311
<212> DNA
<213> Homo sapien

<400> 4972
 gggggcgcgg ccggttactc gcttaccgga ggcttcagtc cccggcggcg 50

 cggcgacagc tagggttcac ggccactggg gcagaggagc cgcgagaaga 100

 tgtgggtttt tggttacggg tccctgatct ggaaggtgga tttcccctat 150

 caggacaagc tggtcggata catcaccaac tacagcaggc gcttctggca 200

 gggcagcacg gaccaccgcg gggtccccgg caagcctgga agagttgtga 250

 ctcttgttga agatcctgcg ggatgtgtat ggggtgttgc ttacagattg 300

 ccagtaggaa aggaagaaga agtaaaagca taccttgact tcagagaaaa 350

 aggaggctac agaaccacaa cagtcatttt ttatccaaaa gatcccacaa 400

 caaaaccatt cagtgtattg ctatatattg gaacatgtga taatcctgat 450

 tatcttggtc ctgcacctct ggaagacatt gctgaacaaa tttttaatgc 500

 agctggtcca agtggaagaa atacagaata tctttttgaa cttgcaaatt 550

 ctattaggaa ccttgtgcca gaagaagcag atgagcatct tttcgctttg 600

 gaaaaattag taaaggaacg tttagaaggg aaacagaacc tcaattgcat 650

 ataatttagt cttcagagaa ttaacttcag tgcacaatga caatatgatt 700

 tggaaatacg tttacttaaa gatcttattt ttaatgtagt gaggatatta 750

 tttaaacttt tattttaact ggaaatgtcc tgaaacacat atttaaaata 800

 ttgggataca gtgaaagaaa aattcaaatt ttaataacat aaagatttcc 850

 taactttatg ttattgaaca cttactcact agaagtgagt tctttagaaa 900

 aatacagtga aggactcagt tcagtcttgt ttttatcaga gtgataatca 950

 tcctgtttca catcccaata ctattttgaa attctaaaca attaaaccaa 1000

 aattccaata aatataaggt tatgccttca atatattcct atacaattct 1050

 gtaaccatgg tttaaaatac acaagcttaa aataacatgc ttagaaatac 1100

 acaataatat gaacagtatt tcagccttaa ttgtgaattt ccttgttatt 1150

 caagtattaa atgaaatctt ttgagttttt agccaaaaat tggcattttt 1200

 aaaatacgaa aatttccttg gaattataat gtactgtacc tcttcttttt 1250

 taaataaagg cattttacta tatggaaaac taaaaaaaaa aaaaaaaaaa 1300

 aaaaaaaaaa a 1311

<210> 4973
<211> 184
<212> PRT
<213> Homo sapien

<400> 4973
 Met Trp Val Phe Gly Tyr Gly Ser Leu Ile Trp Lys Val Asp Phe
   1               5                  10                  15

 Pro Tyr Gln Asp Lys Leu Val Gly Tyr Ile Thr Asn Tyr Ser Arg
                  20                  25                  30

 Arg Phe Trp Gln Gly Ser Thr Asp His Arg Gly Val Pro Gly Lys
                  35                  40                  45

 Pro Gly Arg Val Val Thr Leu Val Glu Asp Pro Ala Gly Cys Val
                  50                  55                  60

 Trp Gly Val Ala Tyr Arg Leu Pro Val Gly Lys Glu Glu Glu Val
                  65                  70                  75

 Lys Ala Tyr Leu Asp Phe Arg Glu Lys Gly Gly Tyr Arg Thr Thr
                  80                  85                  90

 Thr Val Ile Phe Tyr Pro Lys Asp Pro Thr Thr Lys Pro Phe Ser
                  95                 100                 105

 Val Leu Leu Tyr Ile Gly Thr Cys Asp Asn Pro Asp Tyr Leu Gly
                 110                 115                 120

 Pro Ala Pro Leu Glu Asp Ile Ala Glu Gln Ile Phe Asn Ala Ala
                 125                 130                 135

 Gly Pro Ser Gly Arg Asn Thr Glu Tyr Leu Phe Glu Leu Ala Asn
                 140                 145                 150

 Ser Ile Arg Asn Leu Val Pro Glu Glu Ala Asp Glu His Leu Phe
                 155                 160                 165

 Ala Leu Glu Lys Leu Val Lys Glu Arg Leu Glu Gly Lys Gln Asn
                 170                 175                 180

 Leu Asn Cys Ile


<210> 4974
<211> 982
<212> DNA
<213> Homo sapien

<400> 4974
 aaataattaa atataaataa aaataaagca aaatctgttg ggaaacgaga 50

 aaaaggagag gaatttttca ggaataatca taaaaagaaa tgatcatcag 100

 actgaaagtc cagagcctga gaaatgaaaa catattttta agcattggtg 150

 ttgaccatgc agacaaactt ttgttaattc agagcgatac aaaaggcact 200

 ttgaatctat aaaacttgaa aaagttaaaa attgtatgtc ggataaagct 250

 ttaagtcatc tgtcactatt aacctcagtg cagcaattct gactcctgtg 300

 cctggattcc ttttatgata attttgccac ctacaggaca gattaggtgc 350

 tggtcgcctg aattattttg tgttctgaat tattttgagc tctaaaatgg 400

 taaagtacaa atactcattg ttttactgtg cctttggcct tttataaaaa 450

 ggtatttata attcgttgat aaaaaccaat atttgaagct gttgattacc 500

 aacaaaaaag tttcactctc tttatagtgc ttcaggatac aactttttca 550

 gggccttatt agagaaaaac tgattcacat gttattcttc taaagctaaa 600

 ttattaaaat gtaggttgaa agattggatt gattgtgaat ctacactaaa 650

 gatatggttc caggcagacc tccttagaga cctccaggca gacctcctta 700

 ctgtcttcag tgatgtttaa tttcattact gttactgggt gccaagtgtc 750

 tttcatttgg aagtgaactt actccagtta ttgaatgttt atcatatcat 800

 aatttgcatt tttccaacat tgaaggtatt ttaaaaagtc actaagagat 850

 tcattctttt attattcaac tacaaaaaaa tagtgtaatg atcagaattt 900

 aaaatgtgtg attctttttc ttctgtaagt atgtattgct atgataaata 950

 aaaaatggca ggaccattgt ttttattaaa at 982

<210> 4975
<211> 8
<212> PRT
<213> Homo sapien

<400> 4975
 Met Ala Gly Pro Leu Phe Leu Leu
   1               5

<210> 4976
<211> 924
<212> DNA
<213> Homo sapien

<400> 4976
 ctttccttat gtgtagtttc ttcctgtgac agggagaaac ctggctctca 50

 gattgacagg acattcgctt aggccatgtc agtgctgtag gtgaactgtt 100

 caacctgtgc cccagggagg cgcagtcact atggaggcac cttacttcct 150

 taatcgtgta ctgttgtttt tgtgtttgac ctgtagcatc taagtactgg 200

 tttcaaaagt tgcctagatg agttcttttc tttctttcca cctcctgcaa 250

 attatgtgat ttgcataatt tgtacatagt taggttcatt tgttagtttg 300

 tattcctttt ggcttccccc atatcctcgt tgactttttc tttcttttgt 350

 aacttacata tgttatgaaa tttatatgag gatatataat tttcataaat 400

 gtttatggtt tacatgtatt agttgttatt attaagatca ccctgggatt 450

 gactggccaa gcatttggtg gaagatagca ataaataata catcataaaa 500

 gactttaatg taaaaataaa gccatgaaag taccaagaaa taaatcttct 550

 cattttaatt acatcagctt gtctgtgatc atgtagccta aggtaggcca 600

 gagttaattt ttgtgttatc tatacacgtt attgaagcga attataaaat 650

 gttttagcat gttaattact tgtaaattaa tatctacata taaaaatgtg 700

 agcatatatt ctatttagta tattaatcct tcataaacaa gtaatgcaag 750

 ttagtattaa tgatatctta agacttaaca ttcctttttt agtttgtgtt 800

 gaataaatga acatctaaga gttcatgatg atgcttaagg aaagaagcct 850

 catgtttacc tttggaagtt gtaaggcact gactcataaa aattggcaaa 900

 taaaaggaaa gaatcgggca ttta 924

<210> 4977
<211> 31
<212> PRT
<213> Homo sapien

<400> 4977
 Met Leu Lys Glu Arg Ser Leu Met Phe Thr Phe Gly Ser Cys Lys
   1               5                  10                  15

 Ala Leu Thr His Lys Asn Trp Gln Ile Lys Gly Lys Asn Arg Ala
                  20                  25                  30

 Phe


<210> 4978
<211> 2295
<212> DNA
<213> Homo sapien

<400> 4978
 agagaaaaaa tccctgctgc attatctacc cataaaagaa atacagaacc 50

 atctggaagg tgaagaacaa agaaagggaa tcaagccctg ggaatgcaag 100

 tttgttgctt attcctgtga ctgctgccac agggataagg gtgctaggct 150

 tgggtttagg agacttgggt gaaattccag tctacacatg gctagcaagc 200

 tctctgaaaa atggggagag taagtgtgac ctcatggagt ggtgagcgtt 250

 caattatgtc atgtttataa aagtgcctag cactgtacct ggtacatagt 300

 aggggtgtag tagtagtggt ttccttttgt tcagttgcag ggttggggat 350

 tactttaagg cttagactca aagcgatagg aatgaattgc ttggtcagca 400

 gaagtgcaca ctgcacacca gcctcaaggg acaaggtcaa ccacgacacg 450

 tttgcaaagt gtttgtgcgg ggaagaccac tctgatgttt cttacttaaa 500

 ggcagggtct tccaactttg tctgatacgg aatgacttgt tacaatcatt 550

 tcacaggcaa gccaacactc aggcttttga ctaacttgtc tggcgtgttt 600

 ctcaacaact ccattaagaa ttcactgtta gaaatctgat cttttctcct 650

 ctgttgagct ttacttgggc attttattga tttgatatca cttagtagaa 700

 acccattcaa caaaaggtat ctcttcaggc cactagtcaa tacagcattt 750

 tttatttgct gagattttta cttctatttt gccccacatc agctggtaag 800

 ttttataagt aagcaaaaag taggagctat agacaataag gaagcagaat 850

 gaacctctgc aattcatatt tatgtatgat ttcacttgga gtgggaggag 900

 atgttttttt tccccatctt tgaataagta gaaaaacatc tcacgtaacc 950

 tggggtggtg gtggtgaatt ttcagctgaa gggaatcctt cctcgtgaag 1000

 ctcactgcta tcctgttaat ctagcatttt acttttgtgg taagattctg 1050

 ggtggaaagg gaaaatgaaa tgatacagca tctcaaacat aggcatcaag 1100

 attatttccg ttgacctggt gaccaagatt agggtttgcc taacccagag 1150

 atgataatac gtattaatga tgaagggtaa cggccggccc ttggccaagg 1200

 agaactcttc tgaaggggtg ggccatttgc tcacatttat aaagttggtc 1250

 tcagggcgtt gaggggtggg ggtgcaaacg aggtgctttt acctctggct 1300

 tttggggcaa tgacagcagt tttctttctt ggcccttcta aagggttctc 1350

 tgcattctgt ccccctccct gcccccatcc attaaaggag aacgaataaa 1400

 ctgattttac tgttttccaa gaagaaggca taacacattt tatattacca 1450

 gtgcttaata ttttcatgaa ctacagggag cgttcagcct gccgcgagaa 1500

 ggatttggtt ccctggtgac tggccatcca cccagctcaa tctgcaatct 1550

 ctcttggtat gctgctgagt tggtgggacc tgggcaatta caagggaggt 1600

 cactgcaccc ccaggcagtt cccagcaagt gttttttcca atttcactga 1650

 cattctttcc gggctcaact caatttgttt tcaacttctc tatggcaatt 1700

 gatgactgac tgtgtaattc agcaggatct cctgtgaagt gcttcttccc 1750

 cagttgaata ggagctggtg tttgtctaag cctctgctta tgcatgaggt 1800

 ataatgcttt ttatatgtta tataatgctc ttacgcgtta gctatctgaa 1850

 tgatagattt aataaaatat acctcataat attatgggga aaggatgacg 1900

 actgttatag agaggaactt gggagtatca cttctgtaat ccttatctaa 1950

 cctgaatctg ttagcaggaa actgaaaagg cctgtgtatg acaatgagat 2000

 aaacaatttt aatctcttag caatgtcaag tggaaaatct aactacctgc 2050

 cagtagttta agaaatggct aagagatttt gttgggcaca aataatcctg 2100

 agacccagat tgctgagcca agggtaggaa aattggtttt gctatgtgtt 2150

 acagctggga agtgagaagg tcactgtttg acaaactact aaaaaaacct 2200

 tatggattaa acattcgcca gtgtagggga cattttgaat gtgttataat 2250

 tgatatttta gtctatatgc ggccgctgaa cgctttttct tttac 2295

<210> 4979
<211> 56
<212> PRT
<213> Homo sapien

<400> 4979
 Glu Lys Lys Ser Leu Leu His Tyr Leu Pro Ile Lys Glu Ile Gln
   1               5                  10                  15

 Asn His Leu Glu Gly Glu Glu Gln Arg Lys Gly Ile Lys Pro Trp
                  20                  25                  30

 Glu Cys Lys Phe Val Ala Tyr Ser Cys Asp Cys Cys His Arg Asp
                  35                  40                  45

 Lys Gly Ala Arg Leu Gly Phe Arg Arg Leu Gly
                  50                  55

<210> 4980
<211> 1626
<212> DNA
<213> Homo sapien

<400> 4980
 ttacaaccat tgccttggga cacacagagt gaactgtttg agtgataagt 50

 aatttaggta gaaactttac ccttaatttc aaatgatacc aaacagctca 100

 ttactacccc aagggacgct ctccgtagct tctggattcc ccagtttcct 150

 tctagaaaca aggactccaa tagcactata accctaaaca ggccctaacc 200

 cagaagaata caccacaaaa tgcgattgat tttctcaaaa tatcacagtc 250

 ttagacacta tacaaataat tcaagaaaat tctttctacc ctgcagtgga 300

 tatagtattc tattatattc tccagcaaaa cttttaggac ttttcaaact 350

 catttctaag ccaaatagtt tagataaata tttaccctta tatttggggg 400

 gaattcaggc tcaccatttg ccgaggcaag cccatcaaca gtctagaggc 450

 atattctgtg tcattccttc ccgtctcctt catagaatac tactttttcc 500

 ttttgtctcc tggccattct ccatcatctg ctgattattg ctaaccacag 550

 gatgctggca aagcttacag tgataggcac atgtgttcag tgatgtccaa 600

 tacactctta tcacagtggt tattgcttct tactcttttc aaatgcatta 650

 ttctacccct caacctatat ccaatcatta gaactatacc tgactggagc 700

 ccagaacttg ggaccaatac ttaattcaaa tagcaggggc ttgctcacaa 750

 acattaagcc caaaaagaag cacagcactt tgaaaagtca aataggcctt 800

 tggtagctct gtacatttgc aattttacat ttgttattag tttatagcac 850

 taataacact tcagtcgtga atctacagtc tcaatatgat aagtcttaga 900

 acatgttcta gaaatagtgg taccttgctg ctattatact tagtaactta 950

 taccccaata taataataag tattaaatac agattgtgta tgcattcttt 1000

 gtgtgtatat gccaactgta ctacttaacc tcactgatga gcaattagaa 1050

 aaatacacaa attgtcatag tgaaaataag tcttggtcaa ttcagatgat 1100

 acgtgaacct gataaatgct ctaatagata tgctattttg tcctgtattg 1150

 cttgttttac agtatggtgc atgttgtttg ctaagtaaaa tgataataat 1200

 aataaagtat accaatttta aggttagaat taaaattttg cacatatgct 1250

 tcttgatatt ctgaaatgta ttctgtggct taattatctt attcatacac 1300

 atttcacttg gctttttacc cctaggaaat aactgtccaa gtatatatct 1350

 cgtcttcttt cttgtaactt tgattaaact gcttacttca acttacaaca 1400

 ttgtaaagcc agaatacctc attttaacag tgaaaaaaaa tatgatgacc 1450

 tgatgtgttc tcttgtattt gatttgaact acctaaatag gcttaactgt 1500

 aataataaat atacaatttt ggcaggcatt ttttcctttg tttggatgaa 1550

 cattttgtta ttggtccact tctaattttg tcttaaagag ttataaactc 1600

 agtgtcaata aaacatcttg ttatat 1626

<210> 4981
<211> 104
<212> PRT
<213> Homo sapien

<400> 4981
 Met Arg Leu Ile Phe Ser Lys Tyr His Ser Leu Arg His Tyr Thr
   1               5                  10                  15

 Asn Asn Ser Arg Lys Phe Phe Leu Pro Cys Ser Gly Tyr Ser Ile
                  20                  25                  30

 Leu Leu Tyr Ser Pro Ala Lys Leu Leu Gly Leu Phe Lys Leu Ile
                  35                  40                  45

 Ser Lys Pro Asn Ser Leu Asp Lys Tyr Leu Pro Leu Tyr Leu Gly
                  50                  55                  60

 Gly Ile Gln Ala His His Leu Pro Arg Gln Ala His Gln Gln Ser
                  65                  70                  75

 Arg Gly Ile Phe Cys Val Ile Pro Ser Arg Leu Leu His Arg Ile
                  80                  85                  90

 Leu Leu Phe Pro Phe Val Ser Trp Pro Phe Ser Ile Ile Cys
                  95                 100

<210> 4982
<211> 1932
<212> DNA
<213> Homo sapien

<400> 4982
 cctctagctt agcgagcgct ggagtttgaa gagcgggcag tggctgcaca 50

 cgccaaactt tccctatggc ttcggtgacc agggccgtgt ttggagagct 100

 gccctcggga ggagggacag tggagaagtt ccagctgcag tcagacctct 150

 tgagagtgga catcatctcc tggggctgca cgatcacagc cctagaggtc 200

 aaagacaggc aggggagagc ctcggacgtg gtgcttggct tcgccgagtt 250

 ggaaggatac ctccaaaagc agccatactt tggagcagtt attgggaggg 300

 tggccaaccg aatcgccaaa ggaaccttca aggtggatgg gaaggagtat 350

 cacctggcca ttaacaagga acccaacagt ctgcatggag gagtcagagg 400

 gtttgataaa gtgctctgga cccctcgggt gctgtcaaat ggcgtccagt 450

 tctcgcgcat cagtccagat ggtgaagaag gctaccccgg agagttaaaa 500

 gtctgggtga catacaccct ggatggcgga gagctcatag tcaactacag 550

 agcacaagcc agtcaggcca caccagtcaa cctgaccaac cattcttact 600

 tcaacctggc aggccaggct tccccaaata taaatgacca tgaagtcacc 650

 atagaagcgg atacttattt gcctgtggat gaaaccctga ttcctacagg 700

 agaagttgcc ccagtgcaag gcactgcatt cgacctgaga aagccagtgg 750

 agcttggaaa acacctgcag gacttccatc tcaatggttt tgaccacaat 800

 ttctgtctga agggatctaa agaaaagcat ttttgtgcaa gggtgcatca 850

 tgctgcaagc gggcgggtac tagaagtata caccacccag cccggggtcc 900

 agttttacac gggcaacttc ctggatggca cattaaaggg caagaatgga 950

 gctgtctatc ccaagcactc cggtttctgc ctggagactc agaactggcc 1000

 tgatgcagtc aatcagcccc gcttccctcc tgtgctgctg aggcctggtg 1050

 aggagtatga ccacaccacc tggttcaagt tttctgtggc ttaaggaagt 1100

 gtgaagatat gatccagtcc agggctaggc tcagccacct gtctcctgtc 1150

 cagaaaaaag gtgaagatta agaagctttc agaatgattc tatggattaa 1200

 aatcatacaa atggtggctg ttctgagaat cagtctgggt attgatttcc 1250

 ttttccagtg actggctcca ggccatgtct aatgaccagc tcgattccct 1300

 gtgcagttca gagagcaagt gaacccaacc aacaatgtcg tcatctaagc 1350

 cctgacccta gccagggact cccatgctgc tgttggctcc atctctccac 1400

 actgcctctt tcttttcaac tttttgccct tcctttcttt aaagctattc 1450

 tcacattgct tttatttcct cctccttcac ctccaaccac tgtcagcagc 1500

 actctggagt tttcaaatgt cacattagcc tcaccctgca tgctaggaga 1550

 tggacctgtc tctatacagc agtagatgat tgataagtga ggaaactgag 1600

 gcttacagag gttgaagacc aacaagctaa taaataaaaa gttgaggccg 1650

 ggcacggtgg ctcacgcctg taatcccagc actttggaag gccgaggcag 1700

 gcggatcacg aggtcaggag atcgagacca tcctggctaa cacggtgaaa 1750

 ccccgtctct acataaaaaa ttagctgggt gtggtagcac gcacccgtag 1800

 ttccagctac ttgggaggct gaagcaggag aatcgcttga acctgggagg 1850

 tggaggttgc agtgagccga gatcatgcca ctgcactggg caacagagca 1900

 aaactcgatc tcaaaaaaaa aaaaaaaaaa aa 1932

<210> 4983
<211> 342
<212> PRT
<213> Homo sapien

<400> 4983
 Met Ala Ser Val Thr Arg Ala Val Phe Gly Glu Leu Pro Ser Gly
   1               5                  10                  15

 Gly Gly Thr Val Glu Lys Phe Gln Leu Gln Ser Asp Leu Leu Arg
                  20                  25                  30

 Val Asp Ile Ile Ser Trp Gly Cys Thr Ile Thr Ala Leu Glu Val
                  35                  40                  45

 Lys Asp Arg Gln Gly Arg Ala Ser Asp Val Val Leu Gly Phe Ala
                  50                  55                  60

 Glu Leu Glu Gly Tyr Leu Gln Lys Gln Pro Tyr Phe Gly Ala Val
                  65                  70                  75

 Ile Gly Arg Val Ala Asn Arg Ile Ala Lys Gly Thr Phe Lys Val
                  80                  85                  90

 Asp Gly Lys Glu Tyr His Leu Ala Ile Asn Lys Glu Pro Asn Ser
                  95                 100                 105

 Leu His Gly Gly Val Arg Gly Phe Asp Lys Val Leu Trp Thr Pro
                 110                 115                 120

 Arg Val Leu Ser Asn Gly Val Gln Phe Ser Arg Ile Ser Pro Asp
                 125                 130                 135

 Gly Glu Glu Gly Tyr Pro Gly Glu Leu Lys Val Trp Val Thr Tyr
                 140                 145                 150

 Thr Leu Asp Gly Gly Glu Leu Ile Val Asn Tyr Arg Ala Gln Ala
                 155                 160                 165

 Ser Gln Ala Thr Pro Val Asn Leu Thr Asn His Ser Tyr Phe Asn
                 170                 175                 180

 Leu Ala Gly Gln Ala Ser Pro Asn Ile Asn Asp His Glu Val Thr
                 185                 190                 195

 Ile Glu Ala Asp Thr Tyr Leu Pro Val Asp Glu Thr Leu Ile Pro
                 200                 205                 210

 Thr Gly Glu Val Ala Pro Val Gln Gly Thr Ala Phe Asp Leu Arg
                 215                 220                 225

 Lys Pro Val Glu Leu Gly Lys His Leu Gln Asp Phe His Leu Asn
                 230                 235                 240

 Gly Phe Asp His Asn Phe Cys Leu Lys Gly Ser Lys Glu Lys His
                 245                 250                 255

 Phe Cys Ala Arg Val His His Ala Ala Ser Gly Arg Val Leu Glu
                 260                 265                 270

 Val Tyr Thr Thr Gln Pro Gly Val Gln Phe Tyr Thr Gly Asn Phe
                 275                 280                 285

 Leu Asp Gly Thr Leu Lys Gly Lys Asn Gly Ala Val Tyr Pro Lys
                 290                 295                 300

 His Ser Gly Phe Cys Leu Glu Thr Gln Asn Trp Pro Asp Ala Val
                 305                 310                 315

 Asn Gln Pro Arg Phe Pro Pro Val Leu Leu Arg Pro Gly Glu Glu
                 320                 325                 330

 Tyr Asp His Thr Thr Trp Phe Lys Phe Ser Val Ala
                 335                 340

<210> 4984
<211> 2757
<212> DNA
<213> Homo sapien

<400> 4984
 agaaatcgcc gccagggcta ggctggtgtt tgtcctaagt gggtacttgc 50

 ttgggttgag aaatcacatt ttggctattc cccgacttga accaggggat 100

 agaaatcgta gtcaccggct gggcgcagcg gctcatgctg taatcctggc 150

 agtttgggag gccgaggcgg gcagattatt gaggttagga gttcgagacc 200

 agcctggtca atatgatgaa acaccgcctc tagtaaaaat acaaaaatta 250

 tccgggcgtg gtggcgagcg cctgtaatcc cagctactca ggaggctgag 300

 gcagtagaat cccttgaacc tggggtgcgg aggttgcagt gagccaagat 350

 cgcgccactg cactccaggc tgggcgacac ggcgagactc tgtctcaaaa 400

 caaaacaaaa ggaaaagaag agaaaagaaa aagaaacgca ggcaccctga 450

 aatcgaaact tgttaggacc aacaagccaa cgacagacga atctgcgggg 500

 tcctgcgaca gacacgccag ccccgccgcc acagcacagg gttctggagg 550

 tcgagctgtt ctgcgggttc tgcggcggcg ctgggaagag acggcgcccg 600

 ggcagctccc ctgtcaccgg cttggaggag cggcgggctc ccctagccca 650

 gcgccgccgc cgccgcccgg gaacgccagg ctcaccccag ctggggaagc 700

 tccgaatccc tcagatcggc gacctgagtg ctgtcgcccc gagaaaatgg 750

 aggcatcgag caacgagctg tgctgagacc gagagacctc agttctgcga 800

 aatgtcggtg cctggagctt gcgaatgact gcggccggcg ggttgtcaag 850

 gacaacattc cttatggcgc aaccaacagc gctgtcacca agaaactgga 900

 ctctgagaaa aaagagggtt tcggccaccg agaaactccg tgccacatgt 950

 gccgtgacag caaaaccgcc cgctccgcgc cgctggtgaa agagctaacg 1000

 aacgccaggt gctgcgacag tgacaccggg actagaaggc ctcggatgga 1050

 gaatgggacg cccagagcaa gcaggaaaac gttttgtttg gctcaactag 1100

 cgctgtcgca accggaaaac tgtcaggcca gtgctgctgc ggatgtgaga 1150

 aaccggtgat ccgaaggagg agtggcgctg ggcgctggac tcgctggtgt 1200

 gaaaatctgg ctgctctagg acccggcaag cgcgggcacc aggcgaacgc 1250

 cagcgacttt gccagacaaa tgcatgtctt ttttggtcgc cattcaaaga 1300

 tgcagccggc agtcagcccc ggctctgaga aacaagtgga ggtgtcagcc 1350

 ataaaccctc cgttcaggga aaagagagtc gctgcgacgg atcgattggc 1400

 cgttgggtgg aactttcttt ggtggcctag tgactagaaa ataaaaacga 1450

 aaacgaaata aaaaactgct actgacatta ctcccacgct ccctcctcaa 1500

 gtcagtggct tcaggcttaa gaaaacctgt atttttcttg gctgatccgt 1550

 gatccctaat tactgagggc cccgcgaccc accaagtgcg attcgcagag 1600

 ggaaaggagc tggaataagg atccagaatg ggacggattt ggctcctcca 1650

 ggaagaaagc aaaacaaatg caggtcgcga acactttaca ttgcaggaag 1700

 ctgctcttcc agtggccgcg gctgggtcct tccacaccac ctctctgtcc 1750

 taggccttcg tcccggttca gccctcacgg attctaggct agcggtcaac 1800

 aaccgcatcc ctccggaatc tggaaactct aggtccgaga tctcggtgaa 1850

 gaatgaaagg cacagcgccg ctcaacccag gcttcaggcc tgccccgctg 1900

 gtcccgtccc ttccctgtgg gatggaactc tgtgggaatc gctccttatt 1950

 ctgatggttc actcattcag atgtccttga tatttgggga tatttctaaa 2000

 acagctgggg agaaaaatgg actgcgaggc tccggtgttg gacgtgaaat 2050

 tggcagtgag acatccgcct ctaagcccag ggaaaagctt aaattgtggt 2100

 tctctgtctc tagcaccgtg atctttgaaa tgcgttattg attttcttct 2150

 ttcttctggg aaatgcaatg caggtgaact tgtaagtgtt gaatcctccc 2200

 tctcctcact gttcaatcag actgaggcct acttcctttc tgataagaaa 2250

 tatggaactg ccattgctca gtaggaaaat gtcctttcta caagcattca 2300

 tatttcaata aaaatctgca ctttgtgagt tgagccccct caaagagacc 2350

 tacagaccct gccatgagca tctccatcca cactcatcat ttcccatttt 2400

 caccacttct gctcctgtgc aaaccagtac tatccttttc tgggggatcc 2450

 taggcagaag cgatggcagg acaaaggcag agaaggcact gccaggtcct 2500

 gcatgccagt aaaactactc atgtcagctg ttctgcagga tcccatgaga 2550

 aggtgagtca ccagaaaatg cagtttccac atcctgatga tttcatctcc 2600

 ctaccccaac tgatcaattt ctccaatttt ccagcctctc accctccaca 2650

 atccccttaa aaactgtagc ccagaactct ctggaatgat gaatttgaag 2700

 gtttgctcct gtctcctcac tcagaagcct gtaatcatta aactctttct 2750

 ctgatgc 2757

<210> 4985
<211> 2332
<212> DNA
<213> Homo sapien

<400> 4985
 gaaaaagaaa cgcaggcacc ctgaaatcga aacttgttag gaccaacaag 50

 ccaacgacag acgaatctgc ggggtcctgc gacagacaca ccagccccgc 100

 cgccacagca cagggttctg gaggtcgagc tgttctgcgg gttctgcggc 150

 ggcgctggga agagacggcg cccgggcagc tcccctgtca ccggcttgga 200

 ggagcggcgg gctcccctag cccagcgcgc gccgcgccgg gaacgccagg 250

 ctcaccccag ctggggaagc tccgaatccc tcagatcggc gacctgattg 300

 ctgtcgcccc gagaaaatgg aggcatcgag caacgagctg tgctgagacc 350

 gagagacctc agttctgcga aatgtcggtg cctggagctt gcgaatgact 400

 gcggccggcg ggttgtcaag gacaacattc cttatggcgc aaccaacagc 450

 gctgtcacca agaaactgga ctctgagaaa aaagagggtt tcggccaccg 500

 agaaactccg tgccacatgt gccgtgacag caaaaccgcc cgctccgcgc 550

 cgctggtgaa agagctaaag aacgccaggt gctgcgacag tgacaccggg 600

 actagaaggc ctcggatgga gaatgggacg cccagagcaa gcaggaaaac 650

 gttttgtttg gctcaactag cgctgtcgca accggaaaac tgtcaggcca 700

 gtgctgctgc ggatgtgaga aaccggtgat ccgaaggagg agtggcgctg 750

 ggcgctggac tcgctggtgt gaaaatctgg ctgctctagg acccggcaag 800

 cgcgggcacc aggcgaacgc cagcgacttt gccagacaaa tgcatgtctt 850

 ttttggtcgc cattcaaaga tgcagccggc agtcagcccc ggctctgaga 900

 aacaagtgga ggtgtcagcc ataaaccctc cgttcaggga aaagagagtc 950

 gctgcgacgg atcgattggc cgttgggtgg aactttcttt ggtggcctag 1000

 tgactagaaa ataaaaacga aaacgaaata aaaaactgct actgacatta 1050

 ctcccacgct ccctcctcaa gtcagtggct tcaggcttaa gaaaacctgt 1100

 atttttcttg gctgatccgt gatccctaat tactgagggc cccgcgaccc 1150

 accaagtgcg attcgcagag ggaaaggagc tggaataagg atccagaatg 1200

 ggacggattt ggctcctcca ggaagaaagc aaaacaaatg caggtcgcga 1250

 acactttaca ttgcaggaag ctgctcttcc agtggccgcg gctgggtcct 1300

 tccacaccac ctctctgtcc taggccttcg tcccggttca gccctcacgg 1350

 attctaggct agcggtcaac aaccgcatcc ctccggaacc tggaaactct 1400

 aggtccgaga tctcggtgaa gaatgaaagg cacagcgccg ctcaacccag 1450

 gcttcaggcc tgccccgctg gtcccgtccc ttccctgtgg gatggaactc 1500

 tgtgggaatc gctccttatt ctgatggttc actcattcag atgtccttga 1550

 tatttgggga tatttctaaa acagctgggg agaaaaatgg actgcgaggc 1600

 tccggtgttg gacgtgaaat tggcagtgag acatccgcct ctaagcccag 1650

 ggaaaagctt aaattgtggt tctctgtctc tagcaccgtg atctttgaaa 1700

 tgcgttattg attttcttct ttcttctggg aaatgcaatg caggtgaact 1750

 tgtaagtgtt gaatcctccc tctcctcact gttcaatcag actgaggcct 1800

 acttcctttc tgataagaaa tatggaactg ccattgctca gtaggaaaat 1850

 gtcctttcta caagcattca tatttcaata aaaatctgca ctttgtgagt 1900

 tgagccccct caaagagacc tacagaccct gccatgagca tctccatcca 1950

 cactcatcat ttcccatttt caccacttct gctcctgtgc aaaccagtac 2000

 tatccttttc tgggggatcc taggcagaag cgatggcagg acaaaggcag 2050

 agaaggcact gccaggtcct gcatgccagt aaaactactc atgtcagctg 2100

 ttctgcagga tcccatgaga aggtgagtca ccagaaaatg cagtttccac 2150

 atcctgatga tttcatctcc ctaccccaac tgatcaattt ctccaatttt 2200

 ccagcctctc accctccaca atccccttaa aaactgtagc ccagaactct 2250

 ctggaatgat gaatttgaag gtttgctcct gtctcctcac tcagaagcct 2300

 gtaatcatta aactctttct ctgatgcaaa aa 2332

<210> 4986
<211> 131
<212> PRT
<213> Homo sapien

<400> 4986
 Lys Arg Asn Ala Gly Thr Leu Lys Ser Lys Leu Val Arg Thr Asn
   1               5                  10                  15

 Lys Pro Thr Thr Asp Glu Ser Ala Gly Ser Cys Asp Arg His Thr
                  20                  25                  30

 Ser Pro Ala Ala Thr Ala Gln Gly Ser Gly Gly Arg Ala Val Leu
                  35                  40                  45

 Arg Val Leu Arg Arg Arg Trp Glu Glu Thr Ala Pro Gly Gln Leu
                  50                  55                  60

 Pro Cys His Arg Leu Gly Gly Ala Ala Gly Ser Pro Ser Pro Ala
                  65                  70                  75

 Arg Ala Ala Pro Gly Thr Pro Gly Ser Pro Gln Leu Gly Lys Leu
                  80                  85                  90

 Arg Ile Pro Gln Ile Gly Asp Leu Ile Ala Val Ala Pro Arg Lys
                  95                 100                 105

 Trp Arg His Arg Ala Thr Ser Cys Ala Glu Thr Glu Arg Pro Gln
                 110                 115                 120

 Phe Cys Glu Met Ser Val Pro Gly Ala Cys Glu
                 125                 130

<210> 4987
<211> 2027
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 985
<223> Unknown base

<400> 4987
 cccagctaat ttgttaccta cactctaatt aataatcaat aatttcttat 50

 tttaaaaagt agtactattt aatataatca agataggaga tttaaaatga 100

 gcaagtgatt catttgctct tttaaagaag cccgttgact tacgctttta 150

 aaaaagaagt tggtgggtta cctcaattat tgttcatgct taaacatatc 200

 catttgtaca ggcttatttc tacgtgggac ccaatcatat atactatatt 250

 tctcaaataa tttttctaaa actctggcct atattctaaa cacttgacca 300

 acaccttagt tattgaatag gtaaccattt ttaaagtaca tgtggttcat 350

 tttttaaaat tcaatctctc aagaccgtta gatatttaat aatttaagct 400

 gataagggta tcaaaatgca cattaacttt gatcatcatg atttaagttg 450

 taactttgtg ttattatata aatattaggt tgtttataaa tatattgcag 500

 aaagtattct tgttaagctc ttttaaatga ggggactgtg gtttagagtt 550

 atatattttt gcttattttt aaacttcaat tattccattc ttctgcctta 600

 taataaaact tttaaggcag agaactgaac taattataga atttctcctt 650

 tggagagtta taatgttaca tagtgaacat tcttataaaa gaaagaataa 700

 gtttaagttg atgaatattt agctgcaaag attttttact taaaaaaatc 750

 catgaatatc tttgatttta ttataaagca tttgtaaatt atttgcattt 800

 gagctgtaag attcataaac atttacattt cccaatgatt tctattttga 850

 tttttaaaaa atatacaggg caagctacat ttttaaagca ttaatcaaca 900

 actttattat attacacatt ccagtgcaca aacacacaat atcatttaat 950

 actcacagta gtacctgtga aatatatcag atggntattc ctatctctat 1000

 tttacagcag aggaaaccga aattcagaga acttacattt ctaaggttgt 1050

 acagctgcaa aatgaccaaa ttgtgaagtc cctaacatcc aggttttcat 1100

 aatgccagta ctctttctat gacatgttta tgaccctcca aatgtaccaa 1150

 aactacctaa ctaattcact gagaggaagc caactgcaaa aataggattt 1200

 ttaaaagtac aatagagtat tactacattt tatggatttc agacaaagaa 1250

 acctccgttt attatatcct gatggtgagt attgccagct ctaaattatt 1300

 catatttcta agaccaagga aaatataggt aaatgaaaat tttgaaataa 1350

 agaacaatgc cttaatttgt aaaatctatc attgctacca ccctgcccag 1400

 gtctggccat ttgccataaa tgctggtaaa taaatacaat gactgataga 1450

 gttctgtctc ctttctcttt tgctacccaa ccttggttag agcaaccaaa 1500

 tgtctaaaag gcatgtaaca ggagaaaaaa ataaaaacat tagtcaccaa 1550

 ttcgccgatt ataaaaggga tgtagattcc tttaaattat tactgacctt 1600

 ttgaaagcct tcacgtaagt atgcaacaga taaaatgact catttaccca 1650

 caacaataat ctattatcag tcttaagtaa tgtgaattca ctgtatttct 1700

 ttttatacaa cataaaaact tctgctttcc aaacttcttc cttttcacta 1750

 atttatcagc cactttattt atacacagat aacactttta gaaacatttt 1800

 tctttcttgt ccattttttt ctttcaaaaa taaagtttct tagaacctga 1850

 taaaatggaa acttatggta atatgtgttc tggtaggtgt ccaaaaattc 1900

 cacaccatag actatcaatg atatagccaa ataaaggcca ttcaaaaaaa 1950

 tcagtaattg ggattccttg ccttatatct atggtatagt gtacccattt 2000

 ataacggggt tctgccatct tcgaatt 2027

<210> 4988
<211> 8
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 985
<223> Unknown amino acid

<400> 4988
 Pro Ala Asn Leu Leu Pro Thr Leu
   1               5

<210> 4989
<211> 3797
<212> DNA
<213> Homo sapien

<400> 4989
 cctttgcaga aacacccgaa accctcctgc caggaagacc agggcctggg 50

 aagagggtcg ctctccggcc attctcccct caccctcctc accttcctca 100

 catcctgtgc cctgggggac cagcagctgc ttccacccag aacaagcggg 150

 agcctgtgtc aggaaagcat gtcagagcag agctgccaga tgtccgaact 200

 gcggctcctc ctcctgggga aatgccgctc gggaaaaagt gccacaggaa 250

 atgccattct gggcaaacat gtgttcaagt ccaagttcag tgatcagaca 300

 gtgatcaaaa tgtgccagag agagagttgg gtcctgagag aaaggaaggt 350

 tgtggtaatt gacacccctg accttttctc ctcaatagct tgtgctgaag 400

 acaagcaacg caacatccaa cactgcttgg agctctctgc tcccagcctc 450

 catgctctgc tcttggtaat tgccatcggc catttcacaa gggaggatga 500

 ggaaacagcc aagggcatcc aacaagtgtt tggagctgaa gccaggaggc 550

 acatcattat tgtcttcact cggaaggatg atttggggga tgacttgctg 600

 caagatttca ttgaaaaaaa caaacctctc aagcagttgg ttcaagacta 650

 tgagggccga tactgcattt tcaacaacaa gaccaatagt aaggatgagc 700

 agatcaccca ggtgttggag ctccttcgca aggttgagtc tttggtgaat 750

 acgaacggag gaccctatca tgtgaacttc aaaactgaag gcagcaggtt 800

 tcaagattgt gtgaatgaag ctgcatctca agagggagac aagccacagg 850

 gcccaaggga aaggcagctg cagtccacag gacccgagca gaatccgggg 900

 acatcagaac tgacagtcct ccttgtgggg aaacgcggtg ctggaaaaag 950

 tgcagcagga aacagcattc tggggaggca ggcctttcag accggattta 1000

 gtgagcagtc agtaacccag agcttcttgt ctgagagcag aagctggaga 1050

 aaaaagaaag tttcgatcat tgatgctccg gacatctcat ctttaaagaa 1100

 cattgactca gaagttagaa aacacatctg tacaggcccc catgccttcc 1150

 tgctggtgac accactgggc ttttacacta agaatgatga ggcagtgctg 1200

 agcaccatcc aaaacaattt tggagaaaaa ttctttgagt acatgatcat 1250

 acttcttacc aggaaagaag atttagggga tcaggatcta gatacgttct 1300

 taagaaacag caataaagct ctctatggtc tcatccagaa gtgtaaaaac 1350

 agatatagtg ccttcaacta ccgggcaaca ggagaagaag agcaaaggca 1400

 ggcggacgag ctcctggaaa aaattgagag catggtgcat cagaatggga 1450

 acaagcattg cgttttcaga gaaaaagaaa ccctgaacat tgtccttgtg 1500

 gggagaagcg ggactgggaa gagtgcgacc gggaactcta tcctggggag 1550

 cctcgtcttc acctctcggc tccgggccca gccagtcacc aagaccagcc 1600

 agagtggcag gaggacatgg gacggacagg aggtggtggt tgtggacact 1650

 ccttccttca accagatgct ggatgtcgaa aaggacccat cccggttaga 1700

 agaggaggtc aagcgctgtt tgtcctgctg tgaaaaaggg gacacatttt 1750

 ttgtcctggt gttccagctg ggacgattca ctgaagagga caaaacagct 1800

 gtggcgaaac tggaggccat ctttggagca gactttacga aatacgcgat 1850

 tatgctgttc acccggaagg aagacctagg ggcggggaat ttggaagact 1900

 tcatgaagaa ctcagataac aaagcccttc ggcgcatttt taaaaagtgt 1950

 gggcggcgag tttgtgcttt taacaacaaa gaaacaggcc aggcccagga 2000

 aacccaggtg aaagctcttt taacaaaggt caatgatctg agaaaagaaa 2050

 gtgggtggtc cgggtatccc catacacagg agaacgtcag caaactaatt 2100

 aaaaatgtcc aggaaatgtc ccaagccgaa aaactcctta aaaatttaat 2150

 aggtatttta caataggtag ccgaagtgcc tggggtctct tcaattagag 2200

 acaccctcag gttgggggga ggggcggggc atggtacaac ctgtgggaag 2250

 ggaagcgggt tcatggcttt gagggcctga gaggcaaatg catcccgcct 2300

 tgtgatgtat cagctatttg tagataaata aattgcaggt gggggcgaat 2350

 agtagggtat tataaaggag aaagaagata caaggtgggg aaatctggaa 2400

 aaagatttca gacattaggc tgataataag tggtagaatc aagtcacaag 2450

 aatcacctca cttgtgtagg taggttggaa tcaggataga cactgtgatc 2500

 aaggctgagg ccacctggga tgagaatata gatagtcgta caacaaccca 2550

 ggggatccag atacatgaga ccagggcagc gttcagcaca ctcctgggca 2600

 tggcggaagc aggaagcaga ctccagaggg cctccctgtt gtccagggcc 2650

 gttggctccc tgagctctcc tgtctccttt gggatgcgac ttagggctag 2700

 agtgttcttt tcttcacacg ttagccattc cttacggctc ttcacgttcc 2750

 acgcctagat gtgaagtggg acatagtctt ccattgctgg ctgtccctga 2800

 ggaaacagac atgagtcttg gaggttctga atgattttat tgctaattat 2850

 cacagtgaca tagactagaa cagaaattag aagcatagta agattgccaa 2900

 aatcagagaa tcttgcaaag ttctgtaatt ctaagtgttg ttctagattt 2950

 cctctagaga aggttattag aatctccatt gcgtttctct ttctccttct 3000

 ctttcccttg aggttaggaa acaggttaaa actcagagaa ctccaataat 3050

 aatggtttaa aaacatcagg ggcttcctgt atctcctgtc aggaagccga 3100

 ggaataagca ggctggggct ggtgggcgtc aacatcccag ttttgttcta 3150

 tctttctgtc ccacctgcac tgggatgtgg cttctacact cgaatttgct 3200

 tcttggtttc aagacagtgg tgttctttcc atagctgagc agattatttt 3250

 gagaggtggg tgatatgtga gagagaaatc tggaaccttc ttctgggtag 3300

 atacaggata agatagatac agggtaaaat gttgagcact ttgtacatgc 3350

 tttgagagca taatctttgt catctgtttt tttcccctag acaatatcag 3400

 gttaccgtca acattaatcc atttaaaagg acatggactg ttgccattaa 3450

 tacttttgga ttccatataa cccttaacac aataacttct agaaaatgtg 3500

 tgtgccgtag acacaaagaa gggaacaata gacaccaggg tatacttgag 3550

 ggtggagggt ggcaggaggg tgaagattga aaagctgcct attgcgtgtt 3600

 atgctggttt cctgggtgac aaaattacct gtacaccaca cccctgtgac 3650

 acacaactta ctcatgtaac aaacctgtgc atgtacccct tgaacctgaa 3700

 ataaaaattg gaaagtaaaa aaaagtgtgt aaatatattt agttgaatca 3750

 aataataaag atgaatcatt atgaattcaa aaaaaaaaaa aaaaaaa 3797

<210> 4990
<211> 665
<212> PRT
<213> Homo sapien

<400> 4990
 Met Ser Glu Gln Ser Cys Gln Met Ser Glu Leu Arg Leu Leu Leu
   1               5                  10                  15

 Leu Gly Lys Cys Arg Ser Gly Lys Ser Ala Thr Gly Asn Ala Ile
                  20                  25                  30

 Leu Gly Lys His Val Phe Lys Ser Lys Phe Ser Asp Gln Thr Val
                  35                  40                  45

 Ile Lys Met Cys Gln Arg Glu Ser Trp Val Leu Arg Glu Arg Lys
                  50                  55                  60

 Val Val Val Ile Asp Thr Pro Asp Leu Phe Ser Ser Ile Ala Cys
                  65                  70                  75

 Ala Glu Asp Lys Gln Arg Asn Ile Gln His Cys Leu Glu Leu Ser
                  80                  85                  90

 Ala Pro Ser Leu His Ala Leu Leu Leu Val Ile Ala Ile Gly His
                  95                 100                 105

 Phe Thr Arg Glu Asp Glu Glu Thr Ala Lys Gly Ile Gln Gln Val
                 110                 115                 120

 Phe Gly Ala Glu Ala Arg Arg His Ile Ile Ile Val Phe Thr Arg
                 125                 130                 135

 Lys Asp Asp Leu Gly Asp Asp Leu Leu Gln Asp Phe Ile Glu Lys
                 140                 145                 150

 Asn Lys Pro Leu Lys Gln Leu Val Gln Asp Tyr Glu Gly Arg Tyr
                 155                 160                 165

 Cys Ile Phe Asn Asn Lys Thr Asn Ser Lys Asp Glu Gln Ile Thr
                 170                 175                 180

 Gln Val Leu Glu Leu Leu Arg Lys Val Glu Ser Leu Val Asn Thr
                 185                 190                 195

 Asn Gly Gly Pro Tyr His Val Asn Phe Lys Thr Glu Gly Ser Arg
                 200                 205                 210

 Phe Gln Asp Cys Val Asn Glu Ala Ala Ser Gln Glu Gly Asp Lys
                 215                 220                 225

 Pro Gln Gly Pro Arg Glu Arg Gln Leu Gln Ser Thr Gly Pro Glu
                 230                 235                 240

 Gln Asn Pro Gly Thr Ser Glu Leu Thr Val Leu Leu Val Gly Lys
                 245                 250                 255

 Arg Gly Ala Gly Lys Ser Ala Ala Gly Asn Ser Ile Leu Gly Arg
                 260                 265                 270

 Gln Ala Phe Gln Thr Gly Phe Ser Glu Gln Ser Val Thr Gln Ser
                 275                 280                 285

 Phe Leu Ser Glu Ser Arg Ser Trp Arg Lys Lys Lys Val Ser Ile
                 290                 295                 300

 Ile Asp Ala Pro Asp Ile Ser Ser Leu Lys Asn Ile Asp Ser Glu
                 305                 310                 315

 Val Arg Lys His Ile Cys Thr Gly Pro His Ala Phe Leu Leu Val
                 320                 325                 330

 Thr Pro Leu Gly Phe Tyr Thr Lys Asn Asp Glu Ala Val Leu Ser
                 335                 340                 345

 Thr Ile Gln Asn Asn Phe Gly Glu Lys Phe Phe Glu Tyr Met Ile
                 350                 355                 360

 Ile Leu Leu Thr Arg Lys Glu Asp Leu Gly Asp Gln Asp Leu Asp
                 365                 370                 375

 Thr Phe Leu Arg Asn Ser Asn Lys Ala Leu Tyr Gly Leu Ile Gln
                 380                 385                 390

 Lys Cys Lys Asn Arg Tyr Ser Ala Phe Asn Tyr Arg Ala Thr Gly
                 395                 400                 405

 Glu Glu Glu Gln Arg Gln Ala Asp Glu Leu Leu Glu Lys Ile Glu
                 410                 415                 420

 Ser Met Val His Gln Asn Gly Asn Lys His Cys Val Phe Arg Glu
                 425                 430                 435

 Lys Glu Thr Leu Asn Ile Val Leu Val Gly Arg Ser Gly Thr Gly
                 440                 445                 450

 Lys Ser Ala Thr Gly Asn Ser Ile Leu Gly Ser Leu Val Phe Thr
                 455                 460                 465

 Ser Arg Leu Arg Ala Gln Pro Val Thr Lys Thr Ser Gln Ser Gly
                 470                 475                 480

 Arg Arg Thr Trp Asp Gly Gln Glu Val Val Val Val Asp Thr Pro
                 485                 490                 495

 Ser Phe Asn Gln Met Leu Asp Val Glu Lys Asp Pro Ser Arg Leu
                 500                 505                 510

 Glu Glu Glu Val Lys Arg Cys Leu Ser Cys Cys Glu Lys Gly Asp
                 515                 520                 525

 Thr Phe Phe Val Leu Val Phe Gln Leu Gly Arg Phe Thr Glu Glu
                 530                 535                 540

 Asp Lys Thr Ala Val Ala Lys Leu Glu Ala Ile Phe Gly Ala Asp
                 545                 550                 555

 Phe Thr Lys Tyr Ala Ile Met Leu Phe Thr Arg Lys Glu Asp Leu
                 560                 565                 570

 Gly Ala Gly Asn Leu Glu Asp Phe Met Lys Asn Ser Asp Asn Lys
                 575                 580                 585

 Ala Leu Arg Arg Ile Phe Lys Lys Cys Gly Arg Arg Val Cys Ala
                 590                 595                 600

 Phe Asn Asn Lys Glu Thr Gly Gln Ala Gln Glu Thr Gln Val Lys
                 605                 610                 615

 Ala Leu Leu Thr Lys Val Asn Asp Leu Arg Lys Glu Ser Gly Trp
                 620                 625                 630

 Ser Gly Tyr Pro His Thr Gln Glu Asn Val Ser Lys Leu Ile Lys
                 635                 640                 645

 Asn Val Gln Glu Met Ser Gln Ala Glu Lys Leu Leu Lys Asn Leu
                 650                 655                 660

 Ile Gly Ile Leu Gln
                 665

<210> 4991
<211> 2263
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 535-730
<223> Unknown base

<400> 4991
 gcttccctca gagtgagtat cccaagagat cacagtcaaa gtgcatagca 50

 tttatataat ctaatcttgg aagtcacaaa atgtcattct tgtgatactc 100

 tcattggtga agaagtcata aaatcctgct caggttcaaa aagagggtgt 150

 atagaaccca acactcaata ggaagattgt cagagttaca ttgtaagaag 200

 agcatgtagt tgggagatat cattgtggcc attttgggaa agatgtaaca 250

 tgtcacaatg tcatgttctc catcgtctcc ccgttccacc ttgtactggt 300

 ttccaagggt agtcgtttaa aagtaccaca aaaactgggt ggcttggaac 350

 aacagaaatt tattgtttca cagttctgga ggccagaagt tcaaaatgaa 400

 gtgttggcag aaacatgctg cctctaaagg gactgggaaa ggatctgttc 450

 caggcttccc tatcttctgg ttgttccttg ccttctggct gcgtaactct 500

 agtcttcatt tggtgttctc cctgcatgca tggcnnnnnn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 650

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 700

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn catctctacc caacctctgt 750

 aggttccctc aatccaccaa aattttttgg ctccactgga ttatctagca 800

 gttaggaaac caagatcatt aaatgaattc accgcaacta cagtgagact 850

 gactacctta gcttacctct gtgaaaggag ttaagccaaa ggaatctgtg 900

 gaattttgga gagtttggga gcatttgggg gcaggaggca aatgttcttc 950

 ctttaaatca caacacttag ttctcttcca tttataagac tcacccctcc 1000

 atcccaaccc ctgcaccaca ggacaaggaa gtgttcttgg tcttcaactt 1050

 tcatccctga tggtgaaagc agttgctcct gacctatttg cccaccagct 1100

 tctcctctgg agcctgaggc ttctgatgcc tgcctggctg gttctcagta 1150

 agaaggtcaa gttcaaccag aggggagatg ctgatgcctt tcagtactta 1200

 aatatgagtt cagaccctgg ggcctggaca taagatttgg ggtcccctgg 1250

 atataagatt tctgaaaaca ctcagactgt ggagacccct gctgagggag 1300

 aagctccaaa ctgtggcttc aggggaatgc accaaggctc tcattgaggc 1350

 caccttttcc aacaagctcc cctcctgctt ccccatggct ggcatggctg 1400

 aggaaaaagg acactgagca cagcccgtgc atgagcggct tgccatgcaa 1450

 caggataaaa cccataatgc cactcagcaa gccttggttg taaatctagt 1500

 ttgattacat ttgtaatcaa atgatggcca tttgttctgt ttctggtttg 1550

 tgaaccaact gaagacataa gcagggcctc agctaaccca caaatagcac 1600

 atgtgtgcaa actggaaaaa tgaacccttc ttctgggagg acgccagccc 1650

 aggccaggtc acccggcttg gccagcagaa cacagagtgg attttggtcc 1700

 cgtttgttcc ccagtggggt atctatcctt gtgcagggca caagcctaca 1750

 tggtggctct ggtcatatca ttagaaaata gacagaaatg ggctgcacac 1800

 cagaatgaat gaattgaatt gaaagggagg agtgatggtg gaaaaaaaaa 1850

 caagtcaatt catttagact ggtagaacca gaaccactgt gtagtacatc 1900

 caaacggtta aaattccctg gaagatgtta cataatccta tcatggtgtt 1950

 tatttatgga aatctatttt aaaaatttta tgtaatactg cacagtctgt 2000

 ttgcatgatg ccttgtacgt agtagcaact cagtaaatac tttttgaatg 2050

 aactagtata gtattttaat tagctagtct tcatgtactg gtacaaaaga 2100

 acagtgtcat cttacagctg aagtcataga ggggaaatat cccactcaag 2150

 atcatataac attccaggta ctcaggatga atggtttgag gactggtctg 2200

 aattcttcaa aggtttcagc tgtattaaca ttctccatct aataaacttt 2250

 atcttgtcat tgc 2263

<210> 4992
<211> 127
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 41-106
<223> unknown amino acid

<220>
<221> Unsure
<222> 535-730
<223> Unknown amino acid

<400> 4992
 Met Leu Pro Leu Lys Gly Leu Gly Lys Asp Leu Phe Gln Ala Ser
   1               5                  10                  15

 Leu Ser Ser Gly Cys Ser Leu Pro Ser Gly Cys Val Thr Leu Val
                  20                  25                  30

 Phe Ile Trp Cys Ser Pro Cys Met His Gly Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Ser Leu Pro Asn Leu Cys Arg Phe Pro Gln Ser Thr Lys Ile
                 110                 115                 120

 Phe Trp Leu His Trp Ile Ile
                 125

<210> 4993
<211> 7260
<212> DNA
<213> Homo sapien

<400> 4993
 gttccgctgc ccagtcctgc tggtactcac taggtagtag cggcaacgga 50

 cgccatgggg accgcctcgt cgctcgtgag ccccgcgggc ggggaagtga 100

 tcgaggacac gtacggggcg ggcggcggcg aggcctgcga gatcccggtg 150

 gaggtgaagc ccaaggcccg cctgctgcgc aactcgttcc gccgaggcgc 200

 gggggcggca gcaggggccg ggcccgggtc gctgccccgc ggggtgggcg 250

 cgggcgggct gctgggggcc agcttcaagt ccactggctc gtcggtgcca 300

 gagctggagt acgcggcggc cgagtacgag cggctcagga aggagtacga 350

 gatctttcgc gtcagcaaga accaggagtt gttgtccatg ggccgccgcg 400

 aggccaagct ggacacggag aacaagcggc tgcgggccga actgcaggca 450

 cttcaaaaaa cgtatcagaa gatacttcga gaaaaagaaa gtgctttaga 500

 agcgaaatac caagcaatgg agagagcagc aacatttgaa catgacagag 550

 ataaagttaa aaggcaattc aagattttta gggagaccaa agaaaatgaa 600

 attcaggact tactgagggc caagagggag ttggagagca aacttcagag 650

 gctacaggct cagggtatcc aagtatttga tcctggggag tctgattcag 700

 atgacaactg tacagatgtc actggtaagt gtatatccta tttatatttt 750

 gagctttcaa catggctgta atgacatgta gagccaactt tgaattctgc 800

 tagatttctt ttacttatct atattaggtt attgctttaa ctactgttgc 850

 aaatagtgtc gtgtgttctc tctgtcagct gctaagacac ctcttctcca 900

 cgaagtgtat gaatttgggg actgaagttc cttctacctt gtcactctgc 950

 caaccctaac ccataacttt tactctctag tctaagatat ctaccccagc 1000

 tcccaccagc acatctgcat tttagccaag ggaaagaagg aaggggagaa 1050

 cacgttcctt tcccagaagg tacaacctaa gatcacttct caaatcccat 1100

 tagtcagaac tataactggg aagactggat agtgtaatca gcagccaggc 1150

 agacatgtgt ccaactaaaa tgtagtgttc tgttactgaa gaaagaagag 1200

 gagaatggat attggagtta ctagtctctg caatgttatt tctttacata 1250

 atgatgtatt ctttgcaact atcatttaga atacttgcct tatagttcac 1300

 tgagtggttt ccagtatagc cttgtgaact attcaaaaag tatttgtttt 1350

 ataattaaac aaatgaaaca tgttttctgg aaataaaagc ttgaaatcac 1400

 agagtgaaag ggtttacata ttctaagaaa atgttaaagt gtgattgata 1450

 ctgaaaaaag aaaaatattc tattttaaaa tgcagtggaa aaatgtagtc 1500

 actctcccat ttgtaatgaa ctgtaagcat attctcacaa atggatgcat 1550

 tttggagtaa aatatggtaa ctgacagttc cttcttaatt ttcattgtag 1600

 tatcattgga atctgaccaa catcctggaa tttttattgc taacttttaa 1650

 ggaaaaaatg aaggccgggc acggtggctt atgcctgtaa taccagcact 1700

 ttgggaggcc aaggcgggcg gatcacgagg tcaaaagatc aagaccatcc 1750

 tggccaacat ggtgaaaccc cgtctctact aaatacaaaa attagctggg 1800

 catggtggtg cgtgcctgta gtcccagcta ctcgggaggc tgaggcagga 1850

 aaatcacttg aacccaggag gtggaggttg cagtgagcca agatcgcgcc 1900

 accgcactcc agtgtggcaa cagagccaga ctcatctcaa aaaaaaaaaa 1950

 aaaaaaaaaa aagattctta atggccaaga gtagctgaga aaatgctctt 2000

 ttatacccca acacaagtct tagtgattat ttcagtattg acatattcaa 2050

 atgtacagtg tttcaaaact attgtaattg tcttggcaag ttagaaacaa 2100

 attcctttct aggtcttttt tcatttttgt tttaaacatg aagaaggaac 2150

 acttgagggg gaatgtcacc catgtgagat tcaaagagct acaaatagta 2200

 agctcagttt tgccagagat ttagctcaaa taacaattta cttaaggtta 2250

 tcaaggatgt agatattctg acaaatataa ttgattagaa aatcatcatg 2300

 ttcataagta gctattgatt cagacattaa ttttgttgct ctaggaggtt 2350

 gagaaggagg tacttcctgc tgcaaagagt ttatgtccta ataaattatg 2400

 aatattttta tatttatgtg tgttagtaac agtctgcctt tgaggttttt 2450

 tccttcagat tttaactggt gtctaagctg tacagttgga aatgtttttt 2500

 agaatttttt tttgtaaaat gtttttaact tccttcttat tatgatttct 2550

 tttttattgt attcttgttt attttcatct ttctcttttt aatcctctct 2600

 ttgaatttga gatgataacc agaattatgt taatcagtat ctttgaactt 2650

 tgccaaaagt cgatggcaaa gtattttcaa aatcatttga atatttgtaa 2700

 tattttcata ttttttaaaa tcagcaatcc tgttcagtat atgtgatgag 2750

 tttttgaaca ttcaataagt tggctttcac aagataaaaa tctcttgctg 2800

 aacagctgct ggaacccaat gtgaatattg gactggcgga gccttgggaa 2850

 gtgaaccttc cataggaagc atgatccagc ttcagcagtc cttcagaggc 2900

 cctgagtttg cccatagttc tatagatgtg gaaggaccct ttgcaaatgt 2950

 taatagagat gactgggata ttgctgtagc tagtttatta caagttactc 3000

 ctctgttttc acattctctg tggagtaaca ctgtcagatg ttacctcatt 3050

 tatacagatg aaacccagcc tgagatggat cttttcctta aggactattc 3100

 acctaaactt aagagaatgt gcgagacaat gggatatttt ttccatgctg 3150

 tttattttcc aatagatgtt gaaaatcaat acctcactgt aagaaaatgg 3200

 gaaattgaga aaagttcttt agttatttta tttattcact taacattacc 3250

 aagcctttta ttggaagact gtgaagaagc ttttctgaaa aaccctgaag 3300

 gaaaacctcg attaatcttt catcgtttgg aagatggaaa agtcagttct 3350

 gactctgtcc agcaattgat tgatcaagtt tctaatctaa acaagaccag 3400

 caaagccaag atcattgatc actcaggaga tcctgcagaa ggagtatata 3450

 aaacttatat ttgtgtagaa aagattatta aacaggacat actgggtttt 3500

 gagaacacag acttggagac taaggatttg ggcagtgagg attccattcc 3550

 agaagaagat gattttggtg atgttctgtg ggacatacat gatgaacaag 3600

 agcaaatgga aacttttcag caggcttcta attcagccca tgagttggga 3650

 tttgagaaat attaccaacg ccttaatgat ctagtggcag caccagcccc 3700

 gattccacct cttctcgtgt ctggaggacc aggttctggg aagtctcttc 3750

 ttttatcaaa gtggattcaa ttacaacaga agaattcccc caacacactg 3800

 attctttccc attttgtggg aaggcccatg tcaaccagct cagagtcctc 3850

 cttgattatt aaacgactaa ctctaaagtt gatgcagcac tcttggtcag 3900

 tctctgctct gacactggat cctgctaagc ttctggaaga atttccacgt 3950

 tggctggaaa aactctctgc tcgtcatcaa ggcagcatca tcatcgttat 4000

 tgattctata gatcaagttc aggttgtggc ctacacttca tcttgatccc 4050

 ttaagtccaa aagatgcaaa atctattata attgcagaat gccactctgt 4100

 agacattaaa ttgagtaaag agcagtgctg ggagagcagg caatttagat 4150

 aaaatccttc atcagtgttt ccagtgtcaa gatactcttt cattatatag 4200

 acttgttctg cactctatcc gggagtccat ggcaaatgat gtggataaag 4250

 agctaatgaa gcagatcctc tgccttgtca atgttagtca caatggtgtg 4300

 agtgaatcag aactgatgga actctatcct gagatgtcct ggactttctt 4350

 gacctccctt attcacagtt tatacaaaat gtgtttgttg acttatggat 4400

 gtggcttgct taggtttcaa catctgcagg cttgggaaac agtgagattg 4450

 gagtacctgg aaggccccac tgttacttct tcatacaggc aaaagctaat 4500

 caactatttc accttgcagc taagtcagga cagagtgact tggagaagtg 4550

 cagatgaact cccgtggctt tttcagcagc agggaagtaa acagaagctg 4600

 catgattgcc ttcttaatct ctttgtgtct caaaaccttt ataaaagggg 4650

 acactttgct gagttgctga gttattggca gtttgttggc aaagacaaaa 4700

 gtgcaatggc aacagaatac ttcgattcat tgaagcagta tgagaaaaac 4750

 tgcgaaggcg aggacaacat gagttgctta gctgatcttt atgaaacctt 4800

 ggggcgattt ctcaaggatc taggccttct cagtcaggcc atagtacctt 4850

 tgcagaggtc tttagagatt cgagaaacag ctttagatcc cgatcaccca 4900

 agagtagccc agtccctcca ccaactagca agtgtatacg tgcagtggaa 4950

 gaagtttggc aatgcagaac aactgtataa acaggcgttg gaaatctcag 5000

 aaaatgctta tggtgcggac catccatata ctgctcgtga acttgaagca 5050

 cttgcaactt tgtaccagaa acaaaataaa tatgaacaag ctgaacattt 5100

 taggaaaaaa tcctttaaaa ttcatcagaa agctataaag aaaaaaggca 5150

 acttgtacgg atttgccctt ttacgtagac gggctttaca gttagaagag 5200

 cttacattag gtaaggacac acctgataat gctcggaccc tcaatgaact 5250

 gggtgttctc tactatcttc aaaataacct ggaaacagct gaccagtttc 5300

 tgaagcgttc cttagaaatg agggagcgag ttctaggacc agatcaccct 5350

 gactgtgctc agtctttgaa taatctggca gctctatgca atgaaaagaa 5400

 acagtatgat aaagcagaag aactttatga aagagcttta gatattcgga 5450

 gacgtgcatt agctcctgat cacccttctt tggcatatac ggtgaagcat 5500

 cttgccatct tgtataagaa aatggggaaa cttgacaaag ctgtaccttt 5550

 gtatgaattg gctgttgaaa ttcgacagaa atcttttggc ccaaagcacc 5600

 ctagtgtagc tactgccttg gtgaacttag ctgttcttta tagccaaatg 5650

 aaaaaacacg ttgaagcttt gccattatat gaaagagcat taaagattta 5700

 tgaagatagc ctgggtcgga tgcatcctcg agttggagaa acactgaaaa 5750

 atttagctgt gcttagctat gaaggaggag attttgaaaa agctgctgaa 5800

 ttatacaaaa gggcaatgga aataaaagaa gcagaaacat cactcttggg 5850

 tggaaaagct ccttcacgcc attcatcaag tggagacacg tttagcttaa 5900

 aaacagctca ttctcctaat gttttccttc agcaaggaca aaggtaatag 5950

 cagcagttag aattctttgc aaatgtacct taagacaaaa taattaaaca 6000

 tttggaacat ttgaatttga aactttaaaa aaatgttgta cgaaatttta 6050

 ctacgtgtga tttaactgct atttgtatga agttgtattg gattacatta 6100

 agttggaatt gtgattatgt ctgttttagt tgtttaaaag aattttccta 6150

 ttatatggta tccaaggatg tagacacatt agaattataa gaagacatga 6200

 ggagcaaatc atgaagagcg gattggtctt tgttcaacaa gagctggcag 6250

 agtagttaag acaaggagtt caaaaattcc atgaatcttg gccaggcatg 6300

 gtggctcatg cctgtaatcc caccactttg ggagggtgat gcaggaggat 6350

 cacttgaggc caggagttgg agaccagcct ggccaacatg gtgaaaccct 6400

 gtctctacta aaaatacaaa aaaaaattag ctggacctgg tggcgcatgc 6450

 ctgtaatcct agctactcag gaggctgagg catgagaatc gcttgaactc 6500

 agcaagtgga ggttgctatg agctgagatt gtgccagttc attccaccct 6550

 gggcaacagg gtgagactct gtctcaaaaa aaaaaaaaaa aaaaaaagaa 6600

 ttccatgatt cttttgagct ctcaagagct actttagcct tgccattcct 6650

 cttgcttttc agcagtagtc tggcccaatt ctctacctca aaggaaagtt 6700

 tcaaggatta aagggttaat gtttatgaac gattcaaatt gtcttcagtg 6750

 aaacacatta gtcacaagaa tccctgattg ctgcacttta aaaaattctt 6800

 taccttttcc ttgagcagat tggtccagtc cctctgcttt ctgttctgtc 6850

 tacattgtgt attatttatt actatatagt atatgtatct gcataatgtc 6900

 tgaagtcatt aatgcagtaa caggtcaagc tctttagcat tctttgactt 6950

 ttcccaaaat atagatatga cattctcctt tatcttcctt cttagatggc 7000

 ctaaatctgt ctcttcattt acctcaaact caaattagta tgccattttc 7050

 atactgaaaa ttaaatattt ttatggattt tataaatatt gcaacatttt 7100

 agatattgtt ttggaccatt tgtgtattta tatataataa aatcatcaat 7150

 ttaatacttg taagatccta acatgtattg attgtaaaag tgaaatatgt 7200

 aatagccaca cttcactgtt ttaaaataaa agtgcaattt caaaaaaaaa 7250

 aaaaaaaaaa 7260

<210> 4994
<211> 1025
<212> PRT
<213> Homo sapien

<400> 4994
 Met Ile Gln Leu Gln Gln Ser Phe Arg Gly Pro Glu Phe Ala His
   1               5                  10                  15

 Ser Ser Ile Asp Val Glu Gly Pro Phe Ala Asn Val Asn Arg Asp
                  20                  25                  30

 Asp Trp Asp Ile Ala Val Ala Ser Leu Leu Gln Val Thr Pro Leu
                  35                  40                  45

 Phe Ser His Ser Leu Trp Ser Asn Thr Val Arg Cys Tyr Leu Ile
                  50                  55                  60

 Tyr Thr Asp Glu Thr Gln Pro Glu Met Asp Leu Phe Leu Lys Asp
                  65                  70                  75

 Tyr Ser Pro Lys Leu Lys Arg Met Cys Glu Thr Met Gly Tyr Phe
                  80                  85                  90

 Phe His Ala Val Tyr Phe Pro Ile Asp Val Glu Asn Gln Tyr Leu
                  95                 100                 105

 Thr Val Arg Lys Trp Glu Ile Glu Lys Ser Ser Leu Val Ile Leu
                 110                 115                 120

 Phe Ile His Leu Thr Leu Pro Ser Leu Leu Leu Glu Asp Cys Glu
                 125                 130                 135

 Glu Ala Phe Leu Lys Asn Pro Glu Gly Lys Pro Arg Leu Ile Phe
                 140                 145                 150

 His Arg Leu Glu Asp Gly Lys Val Ser Ser Asp Ser Val Gln Gln
                 155                 160                 165

 Leu Ile Asp Gln Val Ser Asn Leu Asn Lys Thr Ser Lys Ala Lys
                 170                 175                 180

 Ile Ile Asp His Ser Gly Asp Pro Ala Glu Gly Val Tyr Lys Thr
                 185                 190                 195

 Tyr Ile Cys Val Glu Lys Ile Ile Lys Gln Asp Ile Leu Gly Phe
                 200                 205                 210

 Glu Asn Thr Asp Leu Glu Thr Lys Asp Leu Gly Ser Glu Asp Ser
                 215                 220                 225

 Ile Pro Glu Glu Asp Asp Phe Gly Asp Val Leu Trp Asp Ile His
                 230                 235                 240

 Asp Glu Gln Glu Gln Met Glu Thr Phe Gln Gln Ala Ser Asn Ser
                 245                 250                 255

 Ala His Glu Leu Gly Phe Glu Lys Tyr Tyr Gln Arg Leu Asn Asp
                 260                 265                 270

 Leu Val Ala Ala Pro Ala Pro Ile Pro Pro Leu Leu Val Ser Gly
                 275                 280                 285

 Gly Pro Gly Ser Gly Lys Ser Leu Leu Leu Ser Lys Trp Ile Gln
                 290                 295                 300

 Leu Gln Gln Lys Asn Ser Pro Asn Thr Leu Ile Leu Ser His Phe
                 305                 310                 315

 Val Gly Arg Pro Met Ser Thr Ser Ser Glu Ser Ser Leu Ile Ile
                 320                 325                 330

 Lys Arg Leu Thr Leu Lys Leu Met Gln His Ser Trp Ser Val Ser
                 335                 340                 345

 Ala Leu Thr Leu Asp Pro Ala Lys Leu Leu Glu Glu Phe Pro Arg
                 350                 355                 360

 Trp Leu Glu Lys Leu Ser Ala Arg His Gln Gly Ser Ile Ile Ile
                 365                 370                 375

 Val Ile Asp Ser Ile Asp Ile Lys Phe Arg Leu Trp Pro Thr Leu
                 380                 385                 390

 His Leu Asp Pro Leu Ser Pro Lys Asp Ala Lys Ser Ile Ile Ile
                 395                 400                 405

 Ala Glu Cys His Ser Val Asp Ile Lys Leu Ser Lys Glu Gln Cys
                 410                 415                 420

 Trp Glu Ser Arg Gln Phe Arg Lys Ile Leu His Gln Cys Phe Gln
                 425                 430                 435

 Cys Gln Asp Thr Leu Ser Leu Tyr Arg Leu Val Leu His Ser Ile
                 440                 445                 450

 Arg Glu Ser Met Ala Asn Asp Val Asp Lys Glu Leu Met Lys Gln
                 455                 460                 465

 Ile Leu Cys Leu Val Asn Val Ser His Asn Gly Val Ser Glu Ser
                 470                 475                 480

 Glu Leu Met Glu Leu Tyr Pro Glu Met Ser Trp Thr Phe Leu Thr
                 485                 490                 495

 Ser Leu Ile His Ser Leu Tyr Lys Met Cys Leu Leu Thr Tyr Gly
                 500                 505                 510

 Cys Gly Leu Leu Arg Phe Gln His Leu Gln Ala Trp Glu Thr Val
                 515                 520                 525

 Arg Leu Glu Tyr Leu Glu Gly Pro Thr Val Thr Ser Ser Tyr Arg
                 530                 535                 540

 Gln Lys Leu Ile Asn Tyr Phe Thr Leu Gln Leu Ser Gln Asp Arg
                 545                 550                 555

 Val Thr Trp Arg Ser Ala Asp Glu Leu Pro Trp Leu Phe Gln Gln
                 560                 565                 570

 Gln Gly Ser Lys Gln Lys Leu His Asp Cys Leu Leu Asn Leu Phe
                 575                 580                 585

 Val Ser Gln Asn Leu Tyr Lys Arg Gly His Phe Ala Glu Leu Leu
                 590                 595                 600

 Ser Tyr Trp Gln Phe Val Gly Lys Asp Lys Ser Ala Met Ala Thr
                 605                 610                 615

 Glu Tyr Phe Asp Ser Leu Lys Gln Tyr Glu Lys Asn Cys Glu Gly
                 620                 625                 630

 Glu Asp Asn Met Ser Cys Leu Ala Asp Leu Tyr Glu Thr Leu Gly
                 635                 640                 645

 Arg Phe Leu Lys Asp Leu Gly Leu Leu Ser Gln Ala Ile Val Pro
                 650                 655                 660

 Leu Gln Arg Ser Leu Glu Ile Arg Glu Thr Ala Leu Asp Pro Asp
                 665                 670                 675

 His Pro Arg Val Ala Gln Ser Leu His Gln Leu Ala Ser Val Tyr
                 680                 685                 690

 Val Gln Trp Lys Lys Phe Gly Asn Ala Glu Gln Leu Tyr Lys Gln
                 695                 700                 705

 Ala Leu Glu Ile Ser Glu Asn Ala Tyr Gly Ala Asp His Pro Tyr
                 710                 715                 720

 Thr Ala Arg Glu Leu Glu Ala Leu Ala Thr Leu Tyr Gln Lys Gln
                 725                 730                 735

 Asn Lys Tyr Glu Gln Ala Glu His Phe Arg Lys Lys Ser Phe Lys
                 740                 745                 750

 Ile His Gln Lys Ala Ile Lys Lys Lys Gly Asn Leu Tyr Gly Phe
                 755                 760                 765

 Ala Leu Leu Arg Arg Arg Ala Leu Gln Leu Glu Glu Leu Thr Leu
                 770                 775                 780

 Gly Lys Asp Thr Pro Asp Asn Ala Arg Thr Leu Asn Glu Leu Gly
                 785                 790                 795

 Val Leu Tyr Tyr Leu Gln Asn Asn Leu Glu Thr Ala Asp Gln Phe
                 800                 805                 810

 Leu Lys Arg Ser Leu Glu Met Arg Glu Arg Val Leu Gly Pro Asp
                 815                 820                 825

 His Pro Asp Cys Ala Gln Ser Leu Asn Asn Leu Ala Ala Leu Cys
                 830                 835                 840

 Asn Glu Lys Lys Gln Tyr Asp Lys Ala Glu Glu Leu Tyr Glu Arg
                 845                 850                 855

 Ala Leu Asp Ile Arg Arg Arg Ala Leu Ala Pro Asp His Pro Ser
                 860                 865                 870

 Leu Ala Tyr Thr Val Lys His Leu Ala Ile Leu Tyr Lys Lys Met
                 875                 880                 885

 Gly Lys Leu Asp Lys Ala Val Pro Leu Tyr Glu Leu Ala Val Glu
                 890                 895                 900

 Ile Arg Gln Lys Ser Phe Gly Pro Lys His Pro Ser Val Ala Thr
                 905                 910                 915

 Ala Leu Val Asn Leu Ala Val Leu Tyr Ser Gln Met Lys Lys His
                 920                 925                 930

 Val Glu Ala Leu Pro Leu Tyr Glu Arg Ala Leu Lys Ile Tyr Glu
                 935                 940                 945

 Asp Ser Leu Gly Arg Met His Pro Arg Val Gly Glu Thr Leu Lys
                 950                 955                 960

 Asn Leu Ala Val Leu Ser Tyr Glu Gly Gly Asp Phe Glu Lys Ala
                 965                 970                 975

 Ala Glu Leu Tyr Lys Arg Ala Met Glu Ile Lys Glu Ala Glu Thr
                 980                 985                 990

 Ser Leu Leu Gly Gly Lys Ala Pro Ser Arg His Ser Ser Ser Gly
                 995                1000                1005

 Asp Thr Phe Ser Leu Lys Thr Ala His Ser Pro Asn Val Phe Leu
                1010                1015                1020

 Gln Gln Gly Gln Arg
                1025

<210> 4995
<211> 6166
<212> DNA
<213> Homo sapien

<400> 4995
 ctgcaaaaat aagtgaaagt gacagtagcc aatactatac aaagctgaac 50

 catgtaattt acatcttagt gaaattaaac atactataac agcttggctt 100

 ccaggcaaca atactattaa atttgcagta gtagattatg acatcatctg 150

 aaaccccagg atacacattt agagctggct attatggttt gtaatctgta 200

 ttgctgttct ggttagtttt tcatttaatt cattgcacgc ttctattaaa 250

 taaaaaaaaa atacaacagc cttggaggat gcgagttttt tgaaaaatct 300

 gttaagcttc aggttgactg atgtcacatt ttagaatcaa taatgataac 350

 ttatgtctga gaaggattca gaggtcagaa ttacattgaa cggtataatc 400

 attcaaatat ttttatggtc attaagtata atttggggag tttttctaac 450

 tcacctttct tttccaaaat gtttcttagc taactaagac tatacaatgg 500

 tggaataaca acaaaaccta ctgcttttag tagagggttt acattataca 550

 gcagcattct caagcaaata cactgtactg agatcattac aagttcaaac 600

 ttttgcaggg gactggggga tggagaggta agcatatttg aacttcaaaa 650

 aactacttcc agaattttgc gtgtaagtca atttctttgg aaaagggatt 700

 taaacggata tctaattttt ttaaaggcct atttttccaa aaattgtgca 750

 gacattgatt cattttaaca gtgttctcgg gttggggagc tttattacaa 800

 tttcttgtgg tgggtaggaa aaaggatcat atagtttgaa tactcccctc 850

 tctctccacc atatgattct aatgttcttg tctaaggaat ctgtgctcct 900

 cttacccatt cccaagactg aactaatcaa aattccccat ttattgcaag 950

 aggacacttg aacatcaggg acatgaaaat agcttggcaa aacttcttca 1000

 accagtgact gccagacatg ggactagaac ctaggcttct tgtcacatag 1050

 cccagggttc tttataaaaa gctatgtgag aaagagaaag acccacagag 1100

 gtaattcaat tagacatagc agaaaaagat tggttcctgc ttctgccgct 1150

 gccgcccccg gatcccagtg gccccggcgt gctcggctcc cacaggcctg 1200

 cagccagcat cgcaccgaac cttcgggggg ccgcggctgg agcgctcggc 1250

 cggcgtggga gcgcaaggcc gcaggtaatc cagggttggg ggtctccggc 1300

 gtgtctttcg ggtcgcgtcc cgcctgggtg ccccggggat tcccatgcag 1350

 aaatggaggg tgcccccagc agaggggaaa actctggcgt gggagaaggt 1400

 gggggcgtgc ccacagctgc gctcgcgggt cgccggctgc accaggcaca 1450

 gctggaaagc accttgcgca agggtctcac ggggtgcaga ctcgcgactc 1500

 ctcccccttc ctcctccttc ccgtatccgc agcgccaggg ctgtgctggt 1550

 ctgggcagta cgcggggaag cggggacccg ctgtcactgc gcctcccgct 1600

 gccgacgccg cctggacggc cgcactctcc ctgcccgaga cccggtgagt 1650

 gcagctcgga ggctggagga cccgatcctc ccaaatgctg ggtgctttga 1700

 taatttatga cccttttagg ctcccttgac ttagagaacc aggaggaaag 1750

 gagtgggagt gtgggttggc ggagcccaga gacttgtgaa tggctgggac 1800

 taaattcaag tttgtaaccc ggactctatc ccatgactaa agaggtcata 1850

 gcagaacacg aaggctgggc ttttggtcta agaaagaata ctaggagaaa 1900

 aaaaaattta tttccacgga atttgttttc gagcgatact gcatgatcag 1950

 gactctgaaa tttttctagc tctgggcgga aaaggacgcc tagggattgt 2000

 ctccatattt aacaggggaa ggccaccggc tgcctgtaag agagaaacgt 2050

 tgcgatgctt gtctatttca cttttgggaa gacaagatta aaggctgctc 2100

 ttgataaaaa acaggacaga aaggttcttg cagttgcttt acatacctgt 2150

 ggcctgagtc gtttgtgcca aggagagtgt aatccacttc cagctgacgc 2200

 ccccagctct ttgcgacgga ttgaggtttg tgtgcaggac gtctggcata 2250

 cggcccatga ggactttgtc gtgtaaagca aatgggaacg ttgaggcatg 2300

 tagaggtttt gaagcagagt gtcggtcctt ccttccatac gcctgaaacg 2350

 cataatccgg ggctttttga gagcaaaaac atagtcagaa atgtgccctg 2400

 agggagcatg tactattttg gcacacatat gtatatatgt atatataatt 2450

 tttaaatttt ttttgagagg ggtttcactc ttgtcgccca ggctggagcg 2500

 caatggcgcg atctcggctc actgcaacct ccacctcccg ggttcaagcg 2550

 attctcttgc ctcagcctcc cgagtagctg ggattacagg cgcccgccgc 2600

 cacgcccggc taatttttgt agagacaggg tttcaccatg ttggccaggc 2650

 tggtcttgaa ctcctgacct caggtgatgc accctccttg gcctcccaaa 2700

 gtgctgagat tacaggcatg agccactgtg cccggcctgg atattttaaa 2750

 tgagaaataa cacaagtaat agtcattctt tgttaggcag aagcatatgc 2800

 tgttatgctg gccattttca ttcacacttg ccagggaaca ctcacatttt 2850

 gtttctgtat atggaggcag ccaagagtat tatgttaatg tttaggaaga 2900

 gaatttcctc gtgattttat tgctgatttc tgaaataatt cagtgtaact 2950

 aattttgact gtatttgcac atctctccaa ttccaaaagc tggcataatt 3000

 ttctgtttgg ttaggaagta ggaattttat gaggactttt attgtaaact 3050

 gtgtcaaggg aaaaatcatc ttatactaaa cgtctttatt gccaaactag 3100

 aataccttca caatctgaac tttctttaga tggcacagat catgaataaa 3150

 cacagaaacc attagcatat tgtgtgctta attaaggctg gaaagtgctg 3200

 aggctttttg caggcgcagt tagcaggcga actggtcagc agggtttctg 3250

 gggaacgtag atttgcgtga caggggccct gtgttgctaa ggaattaatg 3300

 caggcactga gaaaagtctc agcgtcagac actcctccac ctcccgggtc 3350

 ctgcttccct ccctctcccc tttccaggca actcacagtt taggggtgtg 3400

 gttgtgtgtg ttcaagctct tgggttttac atataaatgc ctgagacttt 3450

 tctgcagggt ttaaaaacta acatcttgtc ttacagtctt gtaggatttg 3500

 tcttttagaa tctccagtcc tcacaggaaa accccccaat taaaaaaata 3550

 aaagaataaa gaataaaaag aataccacta ctactataaa aaaaaaaaaa 3600

 atcctctaaa atttgtcttc ccagatcagc agagtgaatt tgaactgtgt 3650

 ggactttttt cctctttctt tcttgagtca tgttagtact gagaactttt 3700

 ttttttttct gtcaaatcat ctgtttgata aataagtcca ggagacttgg 3750

 atcctttcaa cccctgaggc cctaaattag gctgtttttt ttttaacctc 3800

 tgtgtttcca gtaaattcga caagcagaaa ctgcaactaa acggctcagt 3850

 aaaaccgaag tcaaatgttc ctccattaat ctaagaagtt gctctcctaa 3900

 ctcagcagac tccaagaacc tgaatcacaa tctccctcga agatgtacaa 3950

 gatctcagga ggggaagctg ccccctcact ctagatttca cggtggtgat 4000

 aacagccatg aaagcatttc ataggtttct gccttttttt tctctctctt 4050

 tatgtcttgt tttagatgca atcttcttac cgcgaagaag ccaggggaat 4100

 aggtagccac atcttgtttg cagataagaa aggaagctaa cgcagtatct 4150

 gcaaagccag gagtctgact cagtactttt ctcactcatg catacaagca 4200

 gctaaaaatg acacagctta tttaccatgc ccctgacact gcactgagca 4250

 ctttatgagc ttgaactctg ttaatctcac gaccacctca tgaggtaggt 4300

 gctgttatta cttccatttt acagatgggg aaaattgagg tcgagagagg 4350

 ttgcgttact tgctcaacgt catgcaagca gtaaatggga gtgtgggggg 4400

 aggcaatgag atttgactcc aagcagtctg agaccagagg aatgttggat 4450

 tgcaggatgc taaactgctt tcctcagaca caattcatac gtcagaaaat 4500

 gacctacaag taagtgaatg atgacactaa attgcatggt tcttttgtca 4550

 aatgaaattc actgagaggc agatggctgg gtcatgcgtg caggtggctc 4600

 tgcagtggag catttcctgg agctttgaaa tgaagctcca gattgatcag 4650

 acgtgcgtgg ctttagccct gagtgtcctg tgtgttaaag gcttgtgctt 4700

 ctcagaactt gaaatacctt tcagaaagag gctatgcttt tgggagtgca 4750

 atcggtgatt taagtaaacc aatgtgcctc gaaattctct tagatctctt 4800

 aggacctttt gtcttttctc cttcagaaca gagttgttct aaaatcctga 4850

 gtaacaacgt cagtttttac ccttgcttta ctttcttttt ctcatctaca 4900

 gatctccaag tgtggcagct gatttgtata taagagctga aatgcaattt 4950

 tggttaatat agtcacttgg acttgcttat gataaatttg actttcctgg 5000

 cttctttcta ctactcacag cttctagaag gccatctatt tatatattaa 5050

 tcttctggga ccctcaagat gtttgctttg cactattaaa gaattctggt 5100

 cctaagggag gacagctgaa tcataggtta aatgtatcat catctttctc 5150

 atactcatca ctgggagaac aaggtttcct gtcatccttc caattagctg 5200

 tttaactcat ttgcataaga atcattcctg aaacttgacc tattgccatc 5250

 aaatttgtgt agattgaaat ccatttttcc agcttctggc tttcagggcc 5300

 tgagttttat ttgccaagtt agctcctgca tttagtgaag aggttatttt 5350

 tctttaaagt caccagaggc ataaaaaagc catagcgatt cttgcaggga 5400

 gggtgccact tcgggggaat agctgggttg tgtaaggttg gaagccctaa 5450

 agagccggta gcctaaggtt ttcaaagatt tctgagctgc tcttgattcg 5500

 tgtgtatgtt tagtgaaagt ttgttttcag tgcctgtagc tgataccact 5550

 gactctgtga gtaagagtaa gctctctgga tctcaggttt ccctctgcaa 5600

 agtgagctgg actaaaggtt atcttaggtc cctttcaact ttgcactgtc 5650

 aaattgaatt catacacaca gttgacacag aaccctcgtt ttctgaacaa 5700

 aagcatataa accaaatcct gttgccaatc cttgtatgtc agtttcccat 5750

 gggtcttgaa tgcaaataca aatatcgtaa actaaatatt tgtgttttct 5800

 ttcctagact ctccagaaag agcaacagta atggagtaca tgagcactgg 5850

 aagtgacaat aaagaagaga ttgatttatt aattaaacat ttaaatgtgt 5900

 ctgatgtaat agacattatg gaaaatcttt atgcaagtga agagccagca 5950

 gtttatgaac ccagtctaat gaccatgtgt caagacagta atcaaaacga 6000

 tgagcgttct aagtctctgc tgcttagtgg ccaagaggta ccatggttgt 6050

 catcagtcag atatggaact gtggaggatt tgcttgcttt tgcaaaccat 6100

 atatccaaca ctgcaaagca tttttatgga caacgaccac aggaatctgg 6150

 aattttatta aacatg 6166

<210> 4996
<211> 111
<212> PRT
<213> Homo sapien

<400> 4996
 Met Glu Tyr Met Ser Thr Gly Ser Asp Asn Lys Glu Glu Ile Asp
   1               5                  10                  15

 Leu Leu Ile Lys His Leu Asn Val Ser Asp Val Ile Asp Ile Met
                  20                  25                  30

 Glu Asn Leu Tyr Ala Ser Glu Glu Pro Ala Val Tyr Glu Pro Ser
                  35                  40                  45

 Leu Met Thr Met Cys Gln Asp Ser Asn Gln Asn Asp Glu Arg Ser
                  50                  55                  60

 Lys Ser Leu Leu Leu Ser Gly Gln Glu Val Pro Trp Leu Ser Ser
                  65                  70                  75

 Val Arg Tyr Gly Thr Val Glu Asp Leu Leu Ala Phe Ala Asn His
                  80                  85                  90

 Ile Ser Asn Thr Ala Lys His Phe Tyr Gly Gln Arg Pro Gln Glu
                  95                 100                 105

 Ser Gly Ile Leu Leu Asn
                 110

<210> 4997
<211> 4015
<212> DNA
<213> Homo sapien

<400> 4997
 aaccgccaac ggctgtggcg tttaaaccca agccgcagcc gctgctgctc 50

 gccgagctcc cggagctggg tgggggtgcc ccacgctgaa agagagtgat 100

 ggagtgccca gtgatggaaa ctggctcact ttttacctca ggaattaaga 150

 gacatttgaa agacaaaaga atttcaaaga ctactaagtt gaatgtttct 200

 cttgcttcaa aaataaaaac aaaaatacta aataattctt ctattttcaa 250

 aatatcttta aagcacaaca acagggcatt agctcaggct cttagtagag 300

 aaaaagagaa ttctcgaaga attacaactg aaaagatgct attgcaaaaa 350

 gaagtagaga aactgaattt tgagaacaca tttcttcgcc taaagctaaa 400

 taacttgaat aagaagctta tagacataga agctctcatg aacaataact 450

 tgataactgc aattgaaatg agcagtcttt ctgagttcca tcagagttcc 500

 tttctactgt cagctagcaa gaagaaacga attagtaaac agtgcaagtt 550

 gatgcgtctt ccatttgcaa gggttccatt aacttcaaat gatgatgaag 600

 atgaagataa agagaaaatg cagtgtgaca acaatattaa atcaaagaca 650

 ttacctgata ttccctcttc aggatcaaca acacaacctt tatcaactca 700

 ggataattcg gaagtgttat ttcttaaaga aaataatcaa aatgtatatg 750

 gtttagatga ttcagaacat atttcttcta tagttgatgt acctcccaga 800

 gaaagccatt cccactcaga ccaaagttct aagacttctc taatgagtga 850

 gatgagaaac gcccagtcta ttggccgcag atgggagaaa ccatctccta 900

 gtaatgtgac tgaaaggaag aagcgtgggt catcttggga atcaaataat 950

 ctttctgcag acactccctg tgcaacagtt ttagataaac aacacatttc 1000

 aagtccagaa ttaaattgca ataatgagat aaatggtcat actaatgaaa 1050

 caaatactga aatgcaaaga aataaacagg atcttcctgg cttatcttct 1100

 gagtctgcca gagaacctaa tgcagagtgc atgaatcaaa ttgaggataa 1150

 tgatgacttt caattgcaga aaactgtgta tgatgctgac atggatttaa 1200

 ctgctagtga agtcagcaaa attgtcacag tctcaacagg cattaaaaag 1250

 aaaagtaata aaaaaacaaa tgaacatgga atgaaaactt tcagaaaagt 1300

 gaaagattcc agctctgaaa aaaagagaga aagatcaaag agacagttta 1350

 aaaatagttc agatgtcgat attggggaaa agattgaaaa caggacagaa 1400

 agatctgatg tcctggatgg caaaaggggt gcagaagatc ccggttttat 1450

 tttcaataat gaacagctgg ctcagatgaa tgaacagctg gctcaggtga 1500

 atgaactaaa gaaaatgacc cttcaaactg gctttgaaca aggtgacaga 1550

 gaaaatgtac tgtgtaataa aaaggagaaa agaataacaa atgagcaaga 1600

 ggaaacatac tctttatccc aaagttcagg taaatttcac caggagagta 1650

 aatttgataa gggtcagaat tccctaactt gtaataaaag taaagcttct 1700

 agacagacat ttgtgattca caaattagaa aaagataact tactcccaaa 1750

 ccaaaaggat aaagtaacca tttatgaaaa cctagacgtc acaaatgaat 1800

 ttcacacagc caatctttcc accaaagata atggaaattt atgtgattat 1850

 gggacccaca atatattgga tttgaaaaag tatgtcactg atattcaacc 1900

 ctcagagcaa aatgaatcaa acattaataa gcttagaaag aaagtaaacc 1950

 ggaagacaga aataatttct ggaatgaacc acatgtatga ggataatgat 2000

 aaagatgtgg tgcatggcct aaaaaaaggt aatttttttt ttcaaaaccc 2050

 aagaggataa agaacctatc tctgaaaaca tagaagtttc caaagagctt 2100

 caaatcccag ctctttctac tagagataat gaaaatcaat gtgactatag 2150

 gacccagaat gtgttgggtt tgcaaaagca gatcaccaat atgtaccccg 2200

 ttcagcaaaa tgaatcaaaa gttaataaga agcttaggca gaaagtaaat 2250

 cggaagacag aaataatttc tgaagtgaat catttagata atgacaaaag 2300

 tatagaatac acagttaaaa gtcactcact ctttttaacg caaaaagata 2350

 aggaaatcat ccccggaaac ctagaagacc caagtgagtt tgaaacacct 2400

 gctctttcta ccaaagatag tggaaacctg tatgattctg agattcaaaa 2450

 tgttttgggg gtgaaacatg gccatgatat gcaacctgct tgtcaaaatg 2500

 attcaaaaat aggtaagaag cctagactaa atgtatgtca aaagtcagaa 2550

 ataattcctg aaaccaacca aatatatgag aatgataaca aaggtgtaca 2600

 tgacctagaa aaagataact tcttctctct aaccccaaag aataaagaaa 2650

 caatttctga aaatctacaa gtcacaaatg aatttcaaac agttgatctt 2700

 ctcatcaaag ataatggaaa tttatgtgat tatgacaccc agaatatatt 2750

 ggagttgaaa aagtatgtta ctgataggaa atctgctgag caaaatgaat 2800

 caaaaataaa taagctcagg aataaagtga attggaagac agaaataatt 2850

 tctgaaatga accagatata tgaggataat gataaagatg cacatgtcca 2900

 agaaagctat acaaaagatc ttgattttaa agtaaataaa tctaaacaaa 2950

 aacttgaatg ccaagacatt atcaataaac actatatgga agtcaacagt 3000

 aatgaaaagg aaagttgtga tcaaatttta gattcctaca aagtagttaa 3050

 aaaacgtaag aaagaatcat catgcaaggc aaagaacatt ttgacaaaag 3100

 ctaagaacaa acttgcttca cagttaacag aatcttcaca gacatctatc 3150

 tccttagaat ctgatttaaa acatattact agtgaagcag attctgatcc 3200

 aggaaaccca gttgaactat gtaagactca gaagcaaagc actaccactt 3250

 tgaataaaaa agatctccct tttgtggaag aaataaaaga aggagagtgt 3300

 caggttaaaa aggtaaataa aatgacatct aagtcaaaga aaaggaagac 3350

 ctccatagat ccttctccag agagccatga agtaatggaa agaatacttg 3400

 acagcgttca gggaaagtct actgtatctg aacaagctga taaggaaaac 3450

 aatttggaga atgagaaaat ggtcaaaaat aagccagact tttacacaaa 3500

 ggcatttaga tctttgtctg agatacattc acctaacata caagattctt 3550

 cctttgacag tgttcgtgaa ggtttagtac ctttgagcgt ttcttctggt 3600

 aaaaatgtga taataaaaga aaattttgcc ttggagtgct ccccagcctt 3650

 tcaagtaagt gatgatgagc atgagaagat gaacaagatg aaatttaaag 3700

 tcaaccggag aacccaaaaa tcaggaatag gtgatagacc attacaggac 3750

 ttgtcaaata ccagttttgt ttcaaataac actgctgaat ctgaaaataa 3800

 gtcagaagat ctatcttcag aacggacaag cagaagaaga aggtgtactc 3850

 ctttctattt taaagagcca agcctcagag aataacagtg ttttatggac 3900

 aggcacagtg gctcacacct gtaatcccaa tactttgggt ggctgaggtg 3950

 agaggatcac ttgagcccaa gagtcggaga ccagcctggg caacacaggg 4000

 agacgctcac tctac 4015

<210> 4998
<211> 653
<212> PRT
<213> Homo sapien

<400> 4998
 Met Glu Cys Pro Val Met Glu Thr Gly Ser Leu Phe Thr Ser Gly
   1               5                  10                  15

 Ile Lys Arg His Leu Lys Asp Lys Arg Ile Ser Lys Thr Thr Lys
                  20                  25                  30

 Leu Asn Val Ser Leu Ala Ser Lys Ile Lys Thr Lys Ile Leu Asn
                  35                  40                  45

 Asn Ser Ser Ile Phe Lys Ile Ser Leu Lys His Asn Asn Arg Ala
                  50                  55                  60

 Leu Ala Gln Ala Leu Ser Arg Glu Lys Glu Asn Ser Arg Arg Ile
                  65                  70                  75

 Thr Thr Glu Lys Met Leu Leu Gln Lys Glu Val Glu Lys Leu Asn
                  80                  85                  90

 Phe Glu Asn Thr Phe Leu Arg Leu Lys Leu Asn Asn Leu Asn Lys
                  95                 100                 105

 Lys Leu Ile Asp Ile Glu Ala Leu Met Asn Asn Asn Leu Ile Thr
                 110                 115                 120

 Ala Ile Glu Met Ser Ser Leu Ser Glu Phe His Gln Ser Ser Phe
                 125                 130                 135

 Leu Leu Ser Ala Ser Lys Lys Lys Arg Ile Ser Lys Gln Cys Lys
                 140                 145                 150

 Leu Met Arg Leu Pro Phe Ala Arg Val Pro Leu Thr Ser Asn Asp
                 155                 160                 165

 Asp Glu Asp Glu Asp Lys Glu Lys Met Gln Cys Asp Asn Asn Ile
                 170                 175                 180

 Lys Ser Lys Thr Leu Pro Asp Ile Pro Ser Ser Gly Ser Thr Thr
                 185                 190                 195

 Gln Pro Leu Ser Thr Gln Asp Asn Ser Glu Val Leu Phe Leu Lys
                 200                 205                 210

 Glu Asn Asn Gln Asn Val Tyr Gly Leu Asp Asp Ser Glu His Ile
                 215                 220                 225

 Ser Ser Ile Val Asp Val Pro Pro Arg Glu Ser His Ser His Ser
                 230                 235                 240

 Asp Gln Ser Ser Lys Thr Ser Leu Met Ser Glu Met Arg Asn Ala
                 245                 250                 255

 Gln Ser Ile Gly Arg Arg Trp Glu Lys Pro Ser Pro Ser Asn Val
                 260                 265                 270

 Thr Glu Arg Lys Lys Arg Gly Ser Ser Trp Glu Ser Asn Asn Leu
                 275                 280                 285

 Ser Ala Asp Thr Pro Cys Ala Thr Val Leu Asp Lys Gln His Ile
                 290                 295                 300

 Ser Ser Pro Glu Leu Asn Cys Asn Asn Glu Ile Asn Gly His Thr
                 305                 310                 315

 Asn Glu Thr Asn Thr Glu Met Gln Arg Asn Lys Gln Asp Leu Pro
                 320                 325                 330

 Gly Leu Ser Ser Glu Ser Ala Arg Glu Pro Asn Ala Glu Cys Met
                 335                 340                 345

 Asn Gln Ile Glu Asp Asn Asp Asp Phe Gln Leu Gln Lys Thr Val
                 350                 355                 360

 Tyr Asp Ala Asp Met Asp Leu Thr Ala Ser Glu Val Ser Lys Ile
                 365                 370                 375

 Val Thr Val Ser Thr Gly Ile Lys Lys Lys Ser Asn Lys Lys Thr
                 380                 385                 390

 Asn Glu His Gly Met Lys Thr Phe Arg Lys Val Lys Asp Ser Ser
                 395                 400                 405

 Ser Glu Lys Lys Arg Glu Arg Ser Lys Arg Gln Phe Lys Asn Ser
                 410                 415                 420

 Ser Asp Val Asp Ile Gly Glu Lys Ile Glu Asn Arg Thr Glu Arg
                 425                 430                 435

 Ser Asp Val Leu Asp Gly Lys Arg Gly Ala Glu Asp Pro Gly Phe
                 440                 445                 450

 Ile Phe Asn Asn Glu Gln Leu Ala Gln Met Asn Glu Gln Leu Ala
                 455                 460                 465

 Gln Val Asn Glu Leu Lys Lys Met Thr Leu Gln Thr Gly Phe Glu
                 470                 475                 480

 Gln Gly Asp Arg Glu Asn Val Leu Cys Asn Lys Lys Glu Lys Arg
                 485                 490                 495

 Ile Thr Asn Glu Gln Glu Glu Thr Tyr Ser Leu Ser Gln Ser Ser
                 500                 505                 510

 Gly Lys Phe His Gln Glu Ser Lys Phe Asp Lys Gly Gln Asn Ser
                 515                 520                 525

 Leu Thr Cys Asn Lys Ser Lys Ala Ser Arg Gln Thr Phe Val Ile
                 530                 535                 540

 His Lys Leu Glu Lys Asp Asn Leu Leu Pro Asn Gln Lys Asp Lys
                 545                 550                 555

 Val Thr Ile Tyr Glu Asn Leu Asp Val Thr Asn Glu Phe His Thr
                 560                 565                 570

 Ala Asn Leu Ser Thr Lys Asp Asn Gly Asn Leu Cys Asp Tyr Gly
                 575                 580                 585

 Thr His Asn Ile Leu Asp Leu Lys Lys Tyr Val Thr Asp Ile Gln
                 590                 595                 600

 Pro Ser Glu Gln Asn Glu Ser Asn Ile Asn Lys Leu Arg Lys Lys
                 605                 610                 615

 Val Asn Arg Lys Thr Glu Ile Ile Ser Gly Met Asn His Met Tyr
                 620                 625                 630

 Glu Asp Asn Asp Lys Asp Val Val His Gly Leu Lys Lys Gly Asn
                 635                 640                 645

 Phe Phe Phe Gln Asn Pro Arg Gly
                 650

<210> 4999
<211> 5692
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1911-1939, 4889-5198
<223> Unknown base

<400> 4999
 taggaaggcg ccggaagtgg tcccgcagag gcggggtggg agtggggctc 50

 ccgaggcagt gcagttggct gtagctgggc gcctcggtta ggtgcgctgt 100

 cagtcctttc cgagtgcctg gcccagtctc tcccgcctcg gcccaacatg 150

 gacttcagag aaattctcat gatagcttcc aagggacaag gtgtcaacaa 200

 tgtgccgaaa aggtatagtt tggcagtggg gcctccaaaa aaagacccaa 250

 aagttaaagg tgtccaatca gcagctgtac aagcttttct taaaaggaaa 300

 gaagaggagc tgagacgaaa agccttagag gagaaaagga gaaaagagga 350

 actagtgaaa aagcgaattg agctcaaaca tgacaagaaa gcaagagcta 400

 tggccaagag gacaaaggat aatttccatg gttacaatgg gattcctatt 450

 gaggaaaagt caaagaagag gcaggcaaca gaaagccata ccagccaagg 500

 aaccgaccga gagtatgaaa tggaagaaga gaatgaattc ctcgagtaca 550

 atcacgcaga gtcagagcag gagtatgagg aagagcaaga acctcccaaa 600

 gttgaaagca aaccaaaggt cccccttaaa agtgccccac cacccatgaa 650

 cttcactgat ttactcaggc tggctgagaa aaagcagttt gaaccagtgg 700

 aaatcaaggt agtgaagaaa tcagaagagc gacctatgac cgcagaagaa 750

 cttagggagc gagaattcct tgaacgaaag cataggagaa aaaaacttga 800

 gacagatgga aaactacctc caactgtgtc caaaaaggca ccctctcaga 850

 aagaaagtgt gggcacaaaa cttagcaaag gttctggaga caggcatcct 900

 tcttccaaag gaatgcccct tcctcatgct gagaagaaat caagacccag 950

 catggccaat gagaaacacc tcgcttgtct tcatccaaat ccatgccagg 1000

 agagaggatc aaggcaggat ctggcaatag ctcccaaccc tcacttcgtg 1050

 agggccacga caaacctgtt tttaatggag ctggaaagcc tcattccagc 1100

 acctcttcac caagtgtccc aaagacttct gctagcagga ctcagaaatc 1150

 tgctgttgag cacaaagcca aaaaatctct gtcccatcct agccattcca 1200

 ggcctgggcc catggtcacc ccacacaata aggctaagag tccaggtgtc 1250

 aggcagccag gcagcagctc tagctcagcc cctgggcagc ccagcacagg 1300

 ggttgctcga cccacagtta gttctggccc tgtgcctagg cgccagaatg 1350

 gcagctccag ctcaggacct gagcgatcaa tcagtgggtc caagaagcca 1400

 accaatgact caaatccctc taggcggaca gtcagtggta catgtggccc 1450

 tggacaacct gcaagcagct caggtggccc tgggcgaccc atcagtggtt 1500

 cagttagttc tgcaagaccc ttgggcagct ctcgtggccc tggccggcct 1550

 gtgagcagtc cacatgaact tcgacgacca gtgagtggct tgggcccccc 1600

 ggggcggtct gtcagtggcc ctgggagatc cataagtggc tcaattccag 1650

 ctggacggac tgtcagtaat tcagtcccag gaagaccagt gagcagcttg 1700

 ggacctgggc aaacagttag tagctcaggt cccactataa agcctaagtg 1750

 cactgttgtc tccgaaacaa tttcttccaa gaatatcatt agccggtcca 1800

 gcaatggaca gatgaatgga atgaagcctc ccctatctgg ctacagagct 1850

 gcccaaggtc ctcaaaggct tcccttccct actggttaca aaaggcagcg 1900

 agaatatgaa nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc tctgaaatgg 1950

 aagattttat tgaagatgaa ggagagcctc aggaagaaat atccaagcac 2000

 attagagaaa tctttggtta tgaccgaaaa aaatacaaag atgaaagtga 2050

 ttatgcctta cgttacatgg aaagtagttg gaaagagcag cagaaggaag 2100

 aagcaaagag cttaagactg ggtatgcaag aggacttaga ggaaatgaga 2150

 cgtgaagaag aagaaatgca acgtcgaagg gccaagaagc tgaagaggcg 2200

 ttagctgctg cttttatttt tgtgaaattc tagagctgct ctgctgcaag 2250

 gatttcctgc cttcagactg aagaagcccc cttatcattt tagatttata 2300

 cttgggtact caaggagaag gaatgcatac tgtcatttgc aggctgtcat 2350

 ttgagcataa aatattttca gatattttcc agggtgaaat ctgtaatgca 2400

 gatgatataa tgcccacttg tgctcttatg aagttaactg ttcacagatg 2450

 ccagccttga tcctgatgag ctatgcactc taatgtgggg ccactcacca 2500

 gtcagccaat cttttattgt tcctttgcta ctttgaaagg aaaaaaaagg 2550

 ttgtctcttg atttctgtaa ttcttctgct gatctgtgag tagggcactg 2600

 ccctgctccc aatcaaactt agtcttttta tgagaaacct ggaccttcca 2650

 tgaatgttgc cagcaataaa gtgacttgtc ctaatctatg gattgagaac 2700

 ttgaaaatgt agagtagaat ttataactat catatggatg tcatcctgtg 2750

 actttgaagt acaaagtaga ataaattctg tattcatgga ttggatgctg 2800

 agcattctta ctcattaatt taggtggcta ggaattaatg aaaaaatttt 2850

 caagttaaaa tacaggttat aacagtataa tattcttttc taagttttcc 2900

 tttcagattt actgttatgt tggctttagt gtaagacaag gtcactgtgc 2950

 tgattgattt ttatctaaaa aaattcattt ttatatcgaa gaaaaaatat 3000

 tttattcaaa cattagattt gaaagagtaa tagtttataa aataaggaag 3050

 taacatgtga ggctctcccc tcctcccctc ccccatcata aagatatttt 3100

 gaaatcccaa ggtgccctca tacctcttga cattaatgac ttcatttttt 3150

 agcttgaatt tgttagcaaa tattaatggc agaaaaccaa aaactaaatt 3200

 tatggtatcg agagcaccac cttctctttt tgcccatatt gcactttgat 3250

 ttcaaactat gcactgtgaa gagatttttt tccccaggta ggaagggatg 3300

 ttccctgtta tcgttatttt actgagctgt ggaaactcat ttttaccctt 3350

 tttaaagtca taaatatgga cttaatagcc cttaaccttc aagtccaagc 3400

 agttccaatc aggctgactt aggatcatgc tggaaggaag ccaagtctca 3450

 agaactgtca gcaacagaaa atgagatatg atgctagaga gcatttgtcc 3500

 ttgactgtaa gtacagaggc ttaggggaag tgagacataa gcttgtagga 3550

 ataataaacg ttctacaata aacgttttgg ctatcttaag ccattgtatg 3600

 ggggggatta ggaagtagga gggattgtcc tacaacaggc ccttatactt 3650

 caacagccca aatattttgg tttattcctt tttatccata aagtctttat 3700

 tcttcaagtt tgggtattat agattaccat tgttagcctc ccttaatggg 3750

 accatatgag ccaggctttt aagacggact cattttgaat tgagtttcaa 3800

 actttgaaag tgcaaggatt taatttttaa gttgaatccc atgaaaggtg 3850

 tcatcatcac taggaataac accctttgta actacatata gaactgttac 3900

 aatggtagca gaaaatccta ttgatttcat ctcacccatt tcagatacct 3950

 tcagtgaaat taagggtagt gtgatgtccc atgtaataaa acaggcttag 4000

 aacatcaatt cctctgctgc catttatgtg cttttattcc cccttcaaaa 4050

 attttttatt ggatatatat atttttcagt attcagactc tgaaatctgt 4100

 cattacaatc aagtgcttgt cacagctgaa agatttctgg tggcttaaag 4150

 tttactagca gtaaatttat gatatggtac agttctttgt acagaaaggc 4200

 accattatgt tagaataaat ttccagaact tagtgggaag aatcaggttt 4250

 taaccttgtg tgtctgttac ttctgagtgc atttctataa tataaatgtt 4300

 gatttgcgtc aacattataa aagagcactt ctgtggctca tttaaaagaa 4350

 aaaaaaggtt aagtctttta aattttggcc ttgtttccaa atcctgtctt 4400

 ccatgttgtt tttctgcact tcctgaccac tcttataaaa agctcacaaa 4450

 cctttgaaga aactggagta ggctgttatt tcattaaggt ttacaaatta 4500

 aatgcttgat ttttaatgta ttctctactg ttttgatttt tggattttct 4550

 taattcaaca tttgaagatg tgccttttgg gtaatgttaa tcacgaatgt 4600

 agtaatattt catgattgta ataatgttac atgatcatgg gtgtggcatt 4650

 ctctaacaaa tgatgtgaaa ggaaagtagt tttcataaaa ctcatggctc 4700

 tgattgcaca gtcccacttg cttttgatat tgctatgtca aagcaaaggg 4750

 cacttctttt aaggctactt tcagaacttt gtattttcgc taaactataa 4800

 atgcagttgt gtccagttgg aggccagggt accacatgtc acaggcggcc 4850

 ttacatgtgt gccgtgaaaa ggttcaaaga ctgttaacnn nnnnnnnnnn 4900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 4950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5050

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5100

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 5150

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnat 5200

 gtgggaactc aaattttcat ttttaatgta atccccaaga ttttctccaa 5250

 gaaataaatt gttgttttgt attttgtaac ttaaaagcag ctattggtaa 5300

 atttctgaga tatagcagga gaccaaaaca tgtttggaaa gagaataaat 5350

 atatgaagag agactggttg ttttattttc aatgtattga atatattaga 5400

 ctactattta ttttctgagt ggatgtgatt aaatattcag acgtttagtg 5450

 tatgattaag agtgagatag agatttcttt ggagtaatta aatccatcct 5500

 gtcttttaca caatggacaa atcaagttaa aaaaattttt agatagctta 5550

 gcttgttttc tggtgctgtt gacctgcaag agaatatact tttgcatata 5600

 caggtgaaag ttttgcaatt tatgtataca agaaattgta ggcattaaaa 5650

 atattttatt gataaaataa taataataca ataataataa ta 5692

<210> 5000
<211> 733
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 637-646
<223> unknown amino acid

<220>
<221> Unsure
<222> 1911-1939, 4889-5198
<223> Unknown amino acid

<400> 5000
 Arg Glu Gly Ala Gly Ser Gly Pro Ala Glu Ala Gly Trp Glu Trp
   1               5                  10                  15

 Gly Ser Arg Gly Ser Ala Val Gly Cys Ser Trp Ala Pro Arg Leu
                  20                  25                  30

 Gly Ala Leu Ser Val Leu Ser Glu Cys Leu Ala Gln Ser Leu Pro
                  35                  40                  45

 Pro Arg Pro Asn Met Asp Phe Arg Glu Ile Leu Met Ile Ala Ser
                  50                  55                  60

 Lys Gly Gln Gly Val Asn Asn Val Pro Lys Arg Tyr Ser Leu Ala
                  65                  70                  75

 Val Gly Pro Pro Lys Lys Asp Pro Lys Val Lys Gly Val Gln Ser
                  80                  85                  90

 Ala Ala Val Gln Ala Phe Leu Lys Arg Lys Glu Glu Glu Leu Arg
                  95                 100                 105

 Arg Lys Ala Leu Glu Glu Lys Arg Arg Lys Glu Glu Leu Val Lys
                 110                 115                 120

 Lys Arg Ile Glu Leu Lys His Asp Lys Lys Ala Arg Ala Met Ala
                 125                 130                 135

 Lys Arg Thr Lys Asp Asn Phe His Gly Tyr Asn Gly Ile Pro Ile
                 140                 145                 150

 Glu Glu Lys Ser Lys Lys Arg Gln Ala Thr Glu Ser His Thr Ser
                 155                 160                 165

 Gln Gly Thr Asp Arg Glu Tyr Glu Met Glu Glu Glu Asn Glu Phe
                 170                 175                 180

 Leu Glu Tyr Asn His Ala Glu Ser Glu Gln Glu Tyr Glu Glu Glu
                 185                 190                 195

 Gln Glu Pro Pro Lys Val Glu Ser Lys Pro Lys Val Pro Leu Lys
                 200                 205                 210

 Ser Ala Pro Pro Pro Met Asn Phe Thr Asp Leu Leu Arg Leu Ala
                 215                 220                 225

 Glu Lys Lys Gln Phe Glu Pro Val Glu Ile Lys Val Val Lys Lys
                 230                 235                 240

 Ser Glu Glu Arg Pro Met Thr Ala Glu Glu Leu Arg Glu Arg Glu
                 245                 250                 255

 Phe Leu Glu Arg Lys His Arg Arg Lys Lys Leu Glu Thr Asp Gly
                 260                 265                 270

 Lys Leu Pro Pro Thr Val Ser Lys Lys Ala Pro Ser Gln Lys Glu
                 275                 280                 285

 Ser Val Gly Thr Lys Leu Ser Lys Gly Ser Gly Asp Arg His Pro
                 290                 295                 300

 Ser Ser Lys Gly Met Pro Leu Pro His Ala Glu Lys Lys Ser Arg
                 305                 310                 315

 Pro Ser Met Ala Asn Glu Lys His Leu Ala Cys Leu His Pro Asn
                 320                 325                 330

 Pro Cys Gln Glu Arg Gly Ser Arg Gln Asp Leu Ala Ile Ala Pro
                 335                 340                 345

 Asn Pro His Phe Val Arg Ala Thr Thr Asn Leu Phe Leu Met Glu
                 350                 355                 360

 Leu Glu Ser Leu Ile Pro Ala Pro Leu His Gln Val Ser Gln Arg
                 365                 370                 375

 Leu Leu Leu Ala Gly Leu Arg Asn Leu Leu Leu Ser Thr Lys Pro
                 380                 385                 390

 Lys Asn Leu Cys Pro Ile Leu Ala Ile Pro Gly Leu Gly Pro Trp
                 395                 400                 405

 Ser Pro His Thr Ile Arg Leu Arg Val Gln Val Ser Gly Ser Gln
                 410                 415                 420

 Ala Ala Ala Leu Ala Gln Pro Leu Gly Ser Pro Ala Gln Gly Leu
                 425                 430                 435

 Leu Asp Pro Gln Leu Val Leu Ala Leu Cys Leu Gly Ala Arg Met
                 440                 445                 450

 Ala Ala Pro Ala Gln Asp Leu Ser Asp Gln Ser Val Gly Pro Arg
                 455                 460                 465

 Ser Gln Pro Met Thr Gln Ile Pro Leu Gly Gly Gln Ser Val Val
                 470                 475                 480

 His Val Ala Leu Asp Asn Leu Gln Ala Ala Gln Val Ala Leu Gly
                 485                 490                 495

 Asp Pro Ser Val Val Gln Leu Val Leu Gln Asp Pro Trp Ala Ala
                 500                 505                 510

 Leu Val Ala Leu Ala Gly Leu Ser Ser Pro His Glu Leu Arg Arg
                 515                 520                 525

 Pro Val Ser Gly Leu Gly Pro Pro Gly Arg Ser Val Ser Gly Pro
                 530                 535                 540

 Gly Arg Ser Ile Ser Gly Ser Ile Pro Ala Gly Arg Thr Val Ser
                 545                 550                 555

 Asn Ser Val Pro Gly Arg Pro Val Ser Ser Leu Gly Pro Gly Gln
                 560                 565                 570

 Thr Val Ser Ser Ser Gly Pro Thr Ile Lys Pro Lys Cys Thr Val
                 575                 580                 585

 Val Ser Glu Thr Ile Ser Ser Lys Asn Ile Ile Ser Arg Ser Ser
                 590                 595                 600

 Asn Gly Gln Met Asn Gly Met Lys Pro Pro Leu Ser Gly Tyr Arg
                 605                 610                 615

 Ala Ala Gln Gly Pro Gln Arg Leu Pro Phe Pro Thr Gly Tyr Lys
                 620                 625                 630

 Arg Gln Arg Glu Tyr Glu Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                 635                 640                 645

 Xaa Ser Glu Met Glu Asp Phe Ile Glu Asp Glu Gly Glu Pro Gln
                 650                 655                 660

 Glu Glu Ile Ser Lys His Ile Arg Glu Ile Phe Gly Tyr Asp Arg
                 665                 670                 675

 Lys Lys Tyr Lys Asp Glu Ser Asp Tyr Ala Leu Arg Tyr Met Glu
                 680                 685                 690

 Ser Ser Trp Lys Glu Gln Gln Lys Glu Glu Ala Lys Ser Leu Arg
                 695                 700                 705

 Leu Gly Met Gln Glu Asp Leu Glu Glu Met Arg Arg Glu Glu Glu
                 710                 715                 720

 Glu Met Gln Arg Arg Arg Ala Lys Lys Leu Lys Arg Arg
                 725                 730

<210> 5001
<211> 1568
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 104, 112
<223> Unknown base

<400> 5001
 cattagattt cactttttta aaaaacccag tggacattgc tataaataag 50

 atttatttgg ctacaaataa cctgggatgt tgcttattat gattgatgcc 100

 tgcnggtttg tncccaagct gagtgaaatt gaacctcgtc ctccctactc 150

 attttgatga ctgaggctgg tttataagaa aaggaagttt ggagaagaaa 200

 accgagatta gaaaatatca tgttttggtt ggagataaga accagggatg 250

 gcaagtacca gtgtgtacaa atgtatttca cggagtttga aggaacgcat 300

 aatcaagagg gaaaacaatt tgtccttcat tggacgtatt atttggattt 350

 gggtgagcaa caaaatggaa tgtggtctgt taggagcatt ctgtttgttc 400

 ttttgtccct gatgtgatga atcattgcca catgctagat ggactcttca 450

 tatccaggtt ttgtccctca gggctgagca ctgtattaaa gagtttttgt 500

 tgagtcattt aaccttagtg tccacatcca gatcagctgt aaaatgggga 550

 agacgtgtgc tgatttggaa tgaatgcaaa atatcactat cattttccta 600

 attacagagg agcaaaggtt atcttcagcc ctttcagttc tatgctcaca 650

 tattcaaata tcaaatgtaa tttagctgaa gttatttaat aatcaagtct 700

 ttcaatatct gttcaaagaa aaagaacaca ctttgaaaat tctgcaaagc 750

 tgtctcccag tctttaaaat gtctggaagc actctccttc tttacaatac 800

 caacatcact ggcccagaat cttccctgtg ctaggttgta aatataaata 850

 aattacttgt tttgtaaact tttgtaaaga atattttggt agaaatactt 900

 caaacatatt ctttgggtta tatttataca tatgtgaaat aaatatacta 950

 tcaaaaggtt atattttata caaaaagtaa attgctacct tttgtatgct 1000

 aatatgcaaa gttttgtata atatgatggt ttatttttag ctctacactt 1050

 aaaccatagg tggttgagtg ggaacttttg aaaactatca agaggcttgt 1100

 tagacaaatt tatattctga aacctcaata agaaagcatt ccaggtttca 1150

 atccttgttt tttgtcctgc tcccaaattc ttttttaaac ccatagttct 1200

 tgtgtcttat ttgattcttc tgctgtgcac attgtattgg tccttgttgc 1250

 atgtagtcta ctgtgtgttt tccgatttta taaggcagca tttctccata 1300

 caaaaaraaa aaaaatgatg tacatataaa cgcttttrtt gtatggctcc 1350

 tccatgttac tgtatatatc tgccagcact tcccagttac actcctgtga 1400

 gtcagcttat ttttacccta acataaatag tatgttttgt agtagttatc 1450

 aaatttaaga gataaagcaa tcagaatgtt tggattttct tctatcttaa 1500

 tgtgaatttc ataattaatg tctatttatt cagctattca ttaaaataca 1550

 ggattctttg gggaaaaa 1568

<210> 5002
<211> 2320
<212> DNA
<213> Homo sapien

<400> 5002
 gctcagtggg ggcggctact gctcatgtga ttgtggagta gacagttgga 50

 agaagtaccc agtccatttg gagagttaaa actgtgccta acagaggtgt 100

 cctctgactt ttcttctgca agctccatgt tttcacatct tccctttgac 150

 tgtgtcctgc tgctgctgct gctactactt acaaggtcct cagaagtgga 200

 atacagagcg gaggtcggtc agaatgccta tctgccctgc ttctacaccc 250

 cagccgcccc agggaacctc gtgcccgtct gctggggcaa aggagcctgt 300

 cctgtgtttg aatgtggcaa cgtggtgctc aggactgatg aaagggatgt 350

 gaattattgg acatccagat actggctaaa tggggatttc cgcaaaggag 400

 atgtgtccct gaccatagag aatgtgattc tagcagacag tgggatctac 450

 tgctgccgga tccaaatccc aggcataatg aatgatgaaa aatttaacct 500

 gaagttggtc atcaaaccag ccaaggtcac ccctgcaccg actctgcaga 550

 gagacttcac tgcagccttt ccaaggatgc ttaccaccag gggacatggc 600

 ccagcagaga cacagacact ggggagcctc cctgatataa atctaacaca 650

 aatatccaca ttggccaatg agttacggga ctctagattg gccaatgact 700

 tacgggactc tggagcaacc atcagaatag gcatctacat cggagcaggg 750

 atctgtgctg ggctggctct ggctcttatc ttcggcgctt taattttcaa 800

 atggtattct catagcaaag agaagataca gaatttaagc ctcatctctt 850

 tggccaacct ccctccctca ggattggcaa atgcagtagc agagggaatt 900

 cgctcagaag aaaacatcta taccattgaa gagaacgtat atgaagtgga 950

 ggagcccaat gagtattatt gctatgtcag cagcaggcag caaccctcac 1000

 aacctttggg ttgtcgcttt gcaatgccat agatccaacc accttatttt 1050

 tgagcttggt gttttgtctt tttcagaaac tatgagctgt gtcacctgac 1100

 tggttttgga ggttctgtcc actgctatgg agcagagttt tcccattttc 1150

 agaagataat gactcacatg ggaattgaac tgggacctgc actgaactta 1200

 aacaggcatg tcattgcctc tgtatttaag ccaacagagt tacccaaccc 1250

 agagactgtt aatcatggat gttagagctc aaacgggctt ttatatacac 1300

 taggaattct tgacgtgggg tctctggagc tccaggaaat tcgggcacat 1350

 catatgtcca tgaaacttca gataaactag ggaaaactgg gtgctgaggt 1400

 gaaagcataa cttttttggc acagaaagtc taaaggggcc actgattttc 1450

 aaagagatct gtgatccctt tttgtttttt gtttttgaga tggagtcttg 1500

 ctctgttgcc caggctggag tgcaatggca caatctcggc tcactgcaag 1550

 ctccgcctcc tgggttcaag cgattctcct gcctcagcct cctgagtggc 1600

 tgggattaca ggcatgcacc accatgccca gctaatttgt tgtattttta 1650

 gtagagacag ggtttcacca tgttggccag tgtggtctca aactcctgac 1700

 ctcatgattt gcctgcctcg gcctcccaaa gcactgggat tacaggcgtg 1750

 agccaccaca tccagccagt gatccttaaa agattaagag atgactggac 1800

 taggtctacc ttgatcttga agattccctt ggaatgttga gatttaggct 1850

 tatttgagca ctacctgccc aactgtcagt gccagtgcat agcccttctt 1900

 ttgtctccct tatgaagact gccctgcagg gctgagatgt ggcaggagct 1950

 cccagggaaa aaggaagtgc atttgattgg tgtgtattgg ccaagttttg 2000

 cttgttgtgt gcttgaaaga aaatatctct gaccaacttc tgtattcgtg 2050

 gaccaaactg aagctatatt tttcacagaa gaagaagcag tgacggggac 2100

 acaaattctg ttgcctggtg gaaagaaggc aaaggccttc agcaatctat 2150

 attaccagcg ctggatcctt tgacagagag tggtccctaa acttaaattt 2200

 caagacggta taggcttgat ctgtcttgct tattgttgcc ccctgcgcct 2250

 agcacaattt tgacacacaa ttggaactta ctaaaaattt ttttttactg 2300

 ttaaaaaaaa aaaaaaaaaa 2320

<210> 5003
<211> 301
<212> PRT
<213> Homo sapien

<400> 5003
 Met Phe Ser His Leu Pro Phe Asp Cys Val Leu Leu Leu Leu Leu
   1               5                  10                  15

 Leu Leu Leu Thr Arg Ser Ser Glu Val Glu Tyr Arg Ala Glu Val
                  20                  25                  30

 Gly Gln Asn Ala Tyr Leu Pro Cys Phe Tyr Thr Pro Ala Ala Pro
                  35                  40                  45

 Gly Asn Leu Val Pro Val Cys Trp Gly Lys Gly Ala Cys Pro Val
                  50                  55                  60

 Phe Glu Cys Gly Asn Val Val Leu Arg Thr Asp Glu Arg Asp Val
                  65                  70                  75

 Asn Tyr Trp Thr Ser Arg Tyr Trp Leu Asn Gly Asp Phe Arg Lys
                  80                  85                  90

 Gly Asp Val Ser Leu Thr Ile Glu Asn Val Ile Leu Ala Asp Ser
                  95                 100                 105

 Gly Ile Tyr Cys Cys Arg Ile Gln Ile Pro Gly Ile Met Asn Asp
                 110                 115                 120

 Glu Lys Phe Asn Leu Lys Leu Val Ile Lys Pro Ala Lys Val Thr
                 125                 130                 135

 Pro Ala Pro Thr Leu Gln Arg Asp Phe Thr Ala Ala Phe Pro Arg
                 140                 145                 150

 Met Leu Thr Thr Arg Gly His Gly Pro Ala Glu Thr Gln Thr Leu
                 155                 160                 165

 Gly Ser Leu Pro Asp Ile Asn Leu Thr Gln Ile Ser Thr Leu Ala
                 170                 175                 180

 Asn Glu Leu Arg Asp Ser Arg Leu Ala Asn Asp Leu Arg Asp Ser
                 185                 190                 195

 Gly Ala Thr Ile Arg Ile Gly Ile Tyr Ile Gly Ala Gly Ile Cys
                 200                 205                 210

 Ala Gly Leu Ala Leu Ala Leu Ile Phe Gly Ala Leu Ile Phe Lys
                 215                 220                 225

 Trp Tyr Ser His Ser Lys Glu Lys Ile Gln Asn Leu Ser Leu Ile
                 230                 235                 240

 Ser Leu Ala Asn Leu Pro Pro Ser Gly Leu Ala Asn Ala Val Ala
                 245                 250                 255

 Glu Gly Ile Arg Ser Glu Glu Asn Ile Tyr Thr Ile Glu Glu Asn
                 260                 265                 270

 Val Tyr Glu Val Glu Glu Pro Asn Glu Tyr Tyr Cys Tyr Val Ser
                 275                 280                 285

 Ser Arg Gln Gln Pro Ser Gln Pro Leu Gly Cys Arg Phe Ala Met
                 290                 295                 300

 Pro


<210> 5004
<211> 4257
<212> DNA
<213> Homo sapien

<400> 5004
 gacccacgcg tccggtcttt gatgttttct cagttcactg atatcaaaag 50

 aaaggacttt ggcattatgt tcctgcacca ccttgtatct attttcttga 100

 ttaccttttc atatgtcaac aatatggccc gagtaggaac gctggtcctt 150

 tgtcttcatg attcagctga tgctcttctg gaggctgcca aaatggcaaa 200

 ttatgccaag tttcagaaaa tgtgtgatct cctgtttgtt atgtttgccg 250

 tggtttttat caccacacga ctgggtatat ttcctctctg ggtgttaaat 300

 accacattat ttgaaagctg ggagatcgtt ggaccttacc cttcctggtg 350

 ggtttttaac ctactgctat tgctagtaca agggttgaac tgcttctggt 400

 cttacttgat tgtgaaaata gcttgcaaag ctgtttcaag aggcaaggtg 450

 tccaaggatg atcgaagtga tattgagtct agctcagatg aggaggactc 500

 agaacctccg ggaaagaatc cccacactgc gacaaccacc aatgggacca 550

 gtggtaccaa cgggtatctc ctgactggct cctgctccat ggatgattaa 600

 ttactcaaaa ctacaagtcc caagcaaagt gaactatttg ttcctggaag 650

 tatttaataa gttgcaaatg cagttccttt cataatatct cagcaccaga 700

 aacaaaaatt aagattatca aagcattttg aatagtgcac tgccatgtgt 750

 cctgtctgtg aatgaagaag aattaccatt ctctctttgt aggcatgctg 800

 tatgtaattg acacaaggga acagtatttg catttgtact gtcttagaat 850

 attatttatt tttttgtatt tgtaaatctg tggacaaaag agggtttcct 900

 cactcctttt actcactggg ctcatgacag tgaaggagat gctccatctg 950

 cttctccccc tttctcttgc tgtagtccaa tgtgctatga gcatcagctt 1000

 actttgtcac ttagagcaag caaaacccag tgcaagagtc tcgttcagct 1050

 ctaaataggt ttgctttctt ttagttacag tgcccatttt gaaattgcct 1100

 atacagtctt agtgaccatt taaaccggac gaactaggtg tttaattttc 1150

 actcttcatg ttcaattagc agttcaaatt aaagaagatg gttattggag 1200

 aacttttttg aatggttttg tattaaattg ctttgaaata gatttcattt 1250

 cttgtgcaca cagccaagat ttcttcaatg ggtgtgagct agttgagggt 1300

 taaccttgta ggttgcagag tgtatttgtt tgtttgtttg tttttctctg 1350

 tgatgaggtc agtgctctga ttttgaagga ggatattcac tgaagctcat 1400

 agttataaac aaggaaatca ctgttaagaa tgggaatttg tcctgtgttc 1450

 tgggaataac ataaagagag caactgattt cagccaggtt ttgccactac 1500

 cctataatta gtgcagtctt atgttataaa agaaagaagt taactatatt 1550

 tggggacaaa aaaatatttc aagagttgat aaagattacc tgtgcagtgc 1600

 agagcacttt aatgcaacca gctttcaaga aaaagcccta tctagtactt 1650

 gatgttgatg tttttatttt gctgagcaaa ataaagccaa tgggagaagg 1700

 actattttac cctttgcttt tctccttaaa cgtaatccag atgactttcc 1750

 tgttactaaa cactgagcag cattacacta caatgcttct ttggtttcca 1800

 ggaatttttt tcaaatgggg ctgtttctgg aaaaatgaaa aattctattg 1850

 gacaatggca atatcaacaa tgaggaaaat tactgaagaa taagtttcca 1900

 taagtctcct acatagcagt gttatttatg tacagataag aaaaccatat 1950

 gtcagccaaa gattttatct cttcttctaa cttttagtaa gaggaaaaag 2000

 ggattataaa acccttcata aatcaagaag gccatcactt agaacgaacc 2050

 ccaaacaaaa atgccataat ataaatgtgt gaatcagggc tgtgaagaca 2100

 acagcagaaa tgctaacaag cgtgcagaaa caccagagag tgcgtatcct 2150

 gctcagaacc attcacattt aattcaattc ttggaaaaaa ttaaagcttt 2200

 ttgcccacaa tttgcaatct gtgggttaat agttaaaaga atgttcccaa 2250

 ccaaaaaatt cttaccgtaa tattatatct tgccctactt atttacaaaa 2300

 taatatgttt ctgttatggt ccttagtaat aattgaagag gcttagaaat 2350

 acatctgctt gtttattgag aaaacgatgc aaataattct gcttttagag 2400

 ccttgttatt ttatttcaca aaacaggcat atgtctagga gtgtaatttg 2450

 tggatggttg agtttgtaag aacaatcata aaaggacttg ttagtctcca 2500

 gaacatctgc taaaatgcaa gtatatgtat aaggtaatag catattacag 2550

 ctgaaaattt tgagaaggta aaagtttctt aattaaaata tgaacatatt 2600

 tagcttgctt tagtgtctgg ggcaagtcct ctcaatggct aaaattaact 2650

 ttagagatcc atgtgttcag gtttagatca tatgacactc gagcacagaa 2700

 gaataatttc aaggaggtca tcttgtaaat taaaggttta gaagaattgc 2750

 ataaaacgta gtaaatgggg tctgtcatta gcaaaggcaa atctaagcaa 2800

 tcatttttcc ccccagaagt tacttagaag gagaactggg aacacttggg 2850

 gtctctctaa ctgatggcat tcacttcaca cagtcgtcta tgttatccag 2900

 agatttttat ttcattttac attttagggc acagttcttt ggggctaatt 2950

 aaaatggggt ttgcaggctt tttatggtga agaataatat atctctgtct 3000

 atagctttcc catggtagcc tgataaggct gagagagaaa aatatgtgca 3050

 gtatctcatc ctccccctgt accaggccat agctttgaag tgtattttgt 3100

 aaattcaact ataggttagt cagaatgctg tttttcgtta attaacttag 3150

 cctgtgttga tatctcctcc ttcctggtca cattcaaacc ttcccagagt 3200

 acaaaggggt atgtagaaag gattccagaa gaagtaatac tttattctct 3250

 aatgttaata gcttttctgg atctcttagt agggggaaag tagaaaatcg 3300

 agtagaattt ggcctcaggt caataaatga tataaaaaca tgtgttctat 3350

 ttatgtatat atatgtatgt ttctccaaaa agtgataaaa ccaaaatatc 3400

 actgactcat ccctacccat attcttttca taaaacccac tcaccaggta 3450

 caatagaaac ttccctcctt gtttgtcagc ctcctgttca tgttccccac 3500

 acacctgaag gtggtagaat cttttcagcc tcttagccag tgagctaaat 3550

 atggctaagc acaggtcata agagcaccta aggccagcat ataagccaac 3600

 tacagttcac ctttccaaat ttggtcctat ggatgttgag catagggaag 3650

 caactctcag tattttggat tattcaagtg tatgtggtaa aaatgcagat 3700

 gattgctgct ttaccccagg gtttattagc atcctacttc tgctgggctg 3750

 catcattata taatgccaca ggcatctagt caaggtaaag aagccagaaa 3800

 ggttaggcaa gaagtgagat aaaatcagat cacctttgat caaaatggtt 3850

 ggtgaacctc cacatgtcca gttctgttgc caaactttcc attcagagta 3900

 tttggtggag tttgaatttg agcaaactaa atgccttcat cttaggtaga 3950

 aagggcctga atcttccatt ttatattcaa acctcattgt tatttggcct 4000

 aagtaaaaag tcagatttca tttccattta cctgagttcg ctttaaagag 4050

 cttttcaaag agagctttat agacacccac aattgtcccc aatctcttca 4100

 tgatgttgca ttaatagttg tttttgtccc tttcttggaa atgttaatgc 4150

 caaagttgcc tgaacattgg gcggttttct taatttgaag tataaaaatt 4200

 ataaagagta attccaaagg tattaaaaga ttgtttaaca gtaaaaaaaa 4250

 aaaaaaa 4257

<210> 5005
<211> 199
<212> PRT
<213> Homo sapien

<400> 5005
 Asp Pro Arg Val Arg Ser Leu Met Phe Ser Gln Phe Thr Asp Ile
   1               5                  10                  15

 Lys Arg Lys Asp Phe Gly Ile Met Phe Leu His His Leu Val Ser
                  20                  25                  30

 Ile Phe Leu Ile Thr Phe Ser Tyr Val Asn Asn Met Ala Arg Val
                  35                  40                  45

 Gly Thr Leu Val Leu Cys Leu His Asp Ser Ala Asp Ala Leu Leu
                  50                  55                  60

 Glu Ala Ala Lys Met Ala Asn Tyr Ala Lys Phe Gln Lys Met Cys
                  65                  70                  75

 Asp Leu Leu Phe Val Met Phe Ala Val Val Phe Ile Thr Thr Arg
                  80                  85                  90

 Leu Gly Ile Phe Pro Leu Trp Val Leu Asn Thr Thr Leu Phe Glu
                  95                 100                 105

 Ser Trp Glu Ile Val Gly Pro Tyr Pro Ser Trp Trp Val Phe Asn
                 110                 115                 120

 Leu Leu Leu Leu Leu Val Gln Gly Leu Asn Cys Phe Trp Ser Tyr
                 125                 130                 135

 Leu Ile Val Lys Ile Ala Cys Lys Ala Val Ser Arg Gly Lys Val
                 140                 145                 150

 Ser Lys Asp Asp Arg Ser Asp Ile Glu Ser Ser Ser Asp Glu Glu
                 155                 160                 165

 Asp Ser Glu Pro Pro Gly Lys Asn Pro His Thr Ala Thr Thr Thr
                 170                 175                 180

 Asn Gly Thr Ser Gly Thr Asn Gly Tyr Leu Leu Thr Gly Ser Cys
                 185                 190                 195

 Ser Met Asp Asp


<210> 5006
<211> 1438
<212> DNA
<213> Homo sapien

<400> 5006
 cgcagtgccg gcgtcatggc ggcctccgcg cacggctctg tctgggggcc 50

 gttgcggctt ggcatccccg gcctgtgctg ccgccggccg cctctgggtc 100

 tgtacgcgcg catgcggcgg ctgcccgggc cggaggtgtc tgggcggagc 150

 gtggctgcgg ccagcggacc gggcgcctgg ggcactgacc actactgcct 200

 ggagctgctg cggaaacggg attatgaagg ttatttatgc tccctgctgc 250

 tccctgcaga atcccgaagc tctgtttttg cactgagggc ctttaatgtg 300

 gaactggctc aggctggatt actcttgctg ctgtcttgct gtactgtatg 350

 ccactgggat ctgaacacta aacattgcta agaaacccac ccaccaccag 400

 gatatttgga agtaacttca catatggaaa agttaaagac tcagtctctg 450

 agaaaacaat tggactgatg cgaatgcagt tttggaaaaa aactgtggaa 500

 gatatatact gtgacaatcc accacatcag cctgtggcca ttgaactatg 550

 gaaggttgtc ccagctttgg acagcggaaa ctccttcaca gcggctgcta 600

 tgtccttgtg acacgcttcc gtcatttttt ggagcacttt cttattttct 650

 gacacaataa gatattctag gatccttttg aatctctccc ctgcctcacc 700

 tttggaatcg cccatttctc gagagccctg attcctttaa ggagaatggt 750

 agtagagaca agtgtctggg cactaggctg ttaaaagaca taatctgact 800

 aaaagatggc ttatgaaaat cgtcgatgaa agagaaaaaa atctggatga 850

 caaagcatat cgtaatatca aggaactgga aaattatgct gaaaacacac 900

 agagctctct tctttactta acactagaaa tattgggtat aaaggatctt 950

 catgcagatc atgctgcaag tcatattgga aaagcacaag gcattgtcac 1000

 ttgcttgaga gcaacaccat atcatgggag cagaagaaag gtgttccttc 1050

 ccatggatat ttgtatgctg catggtgttt cacaagagga ctttctacgg 1100

 aggaaccaag ataaaaatgt gagagatgta atatatgaca ttgccagtca 1150

 agcacacttg cacctaaagc atgctaggtc ctttcacaaa actgttcctg 1200

 tgaaagcatt tcctgctttt cttcagacgg tttctctaga ggactttcta 1250

 aagaaaattc agcgagtgga ttttgatata ttccacccat ctttacagca 1300

 gaagaataca ttacttccat tatatttgta tattcagtca tggagaaaaa 1350

 catattaaaa taatttcatg gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1400

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1438

<210> 5007
<211> 121
<212> PRT
<213> Homo sapien

<400> 5007
 Met Ala Ala Ser Ala His Gly Ser Val Trp Gly Pro Leu Arg Leu
   1               5                  10                  15

 Gly Ile Pro Gly Leu Cys Cys Arg Arg Pro Pro Leu Gly Leu Tyr
                  20                  25                  30

 Ala Arg Met Arg Arg Leu Pro Gly Pro Glu Val Ser Gly Arg Ser
                  35                  40                  45

 Val Ala Ala Ala Ser Gly Pro Gly Ala Trp Gly Thr Asp His Tyr
                  50                  55                  60

 Cys Leu Glu Leu Leu Arg Lys Arg Asp Tyr Glu Gly Tyr Leu Cys
                  65                  70                  75

 Ser Leu Leu Leu Pro Ala Glu Ser Arg Ser Ser Val Phe Ala Leu
                  80                  85                  90

 Arg Ala Phe Asn Val Glu Leu Ala Gln Ala Gly Leu Leu Leu Leu
                  95                 100                 105

 Leu Ser Cys Cys Thr Val Cys His Trp Asp Leu Asn Thr Lys His
                 110                 115                 120

 Cys


<210> 5008
<211> 1581
<212> DNA
<213> Homo sapien

<400> 5008
 cattcttgag tttgataaag taattcatac aaagtattgt cctcaaataa 50

 gtcttcctta gctaaatgca atttaaaatt attcaaagat cctagggcac 100

 ttctagtttc acgtaaatat tcatattagg tggttctctt catccatttg 150

 ttttcacact gatacataaa aattaacagc agtctaatct agtgacacct 200

 cagtcatatt tcgctataga ttttacctca aatcagtcca agactttttc 250

 agagatcacc atttgtcttg aaaggtttat ttcgttatta aactgcctac 300

 ttataagtaa ttaagagaaa ttaagaaagt agtatgcatt tttaattgaa 350

 attgttttac attctttgta taataaacct aaaaacaaac atgtcataaa 400

 caaattgacg taaagatata aaatgccaaa tgaagtattc caaattttct 450

 attctaatta tttagcttca ccatcattgt ggaaaaaaat actagatcct 500

 gcttagtatt atatattttt cctagtggat cagtgagtaa taagtaccaa 550

 acactagact agaaggtaat ttctacattg tttagaaagg gtgaaacaat 600

 ttatcccctc tggtattgtt ctagcataag ctttagttat acaatgatta 650

 agatagaaaa cttcatatat aaatttgata agcaaaccca catttatagc 700

 tgcagctaaa atatgtttcc ttagggcaca gtaatccttt ctgtgaattt 750

 tgaccttgtt tgtgtttttg tgaatgaagc tatatgtcta atcaaaaatg 800

 attataaaag aggctcatct ctgacatcat tccaaaaata cattcattga 850

 tctcttttta agaaacatct gttattcact gggcattggg actttttgtg 900

 agtaatttga attgaaattt tatgagctat ccaagaattc tgtatggtct 950

 attattttca agtcaaaatt tccagtaagg atttacttta catttcattt 1000

 ggataaatga atcattatat aggtatgtct ttgcttccat tttgagacat 1050

 ttagattttt acagcctgtt tctatagcat ttgatgttac aactctaagc 1100

 gtagttcaaa gacatttaaa ttgacaagtt accagttaaa gaatttagaa 1150

 tatattagat cccatctagt attatatatt ttttctagtt gatcattgag 1200

 cagtaaatac caaatactcg attagaaggt aatttttaca ttgttttgaa 1250

 agggtgaaac aatttatctc ctctggtatt attcttaaac cacagatagg 1300

 gatagtaggg tagtgaaacg aataaatacc tggtagaaga caagagactt 1350

 gggctctaca cctggctctg ccactgattt gctaagtcat attggcaatc 1400

 accacaccct tcagggaatt agtttcatct gtaaaatgca gcggttagta 1450

 ctataaaatc atacaaattt ctttgtgctt tgagaatcta taaaggaatg 1500

 tctgttgata ttctgagtcg attttcattt gcttttgttc cagaacggtt 1550

 aaaataaagc atattatttc atttaaaaag t 1581

<210> 5009
<211> 19
<212> PRT
<213> Homo sapien

<400> 5009
 Ile Leu Glu Phe Asp Lys Val Ile His Thr Lys Tyr Cys Pro Gln
   1               5                  10                  15

 Ile Ser Leu Pro


<210> 5010
<211> 7122
<212> DNA
<213> Homo sapien

<400> 5010
 actgggagaa cagaagactt cacaatttaa tgcctcagtt tttaaaaaag 50

 gatccttaca cttcatgtct cctagccatc agaagaggaa tgagacagca 100

 aaagttcaaa tggcctgttt caagtttctg atataaaacg atgacatttt 150

 caggaaaatc ctgcatttcc agagagagac tggctggtta aatttctgaa 200

 agaggacacc agctaaaaga aggtattgca tctcacccga gcagactgtg 250

 tctgtggaaa gtgtaagccc cttgccagaa gagcagcttc ccagcaaagg 300

 cagagggtga aaacagcaaa ggtcttaaga cactggggac ctagagtcaa 350

 aagggacctc ctccagggaa aacgctgtgt gagaaatggc ctcattcggt 400

 gactgtgagt gacacagcag aaagttgggt cattccggct gcttttttga 450

 gaagtccctg aagagatcaa taacagcaag agggaacctg gcaaggaagc 500

 tattcctata atccaggaaa gagatgagga aggcttggac caggtggtag 550

 tggtgtcagg tagtcaaatg ctgggtatat tttgaagata caccccatag 600

 gatttgctcc acattgaatg tggaatgctg gaagagagat aaagtgtacc 650

 tgtcacatac tttttgagtt ttatttattt tcttagaagt aagtacacaa 700

 agagatgcta cctaggagaa gggtattctt ttcactattc tttcaaattt 750

 tctgtatgtt cgaacatttt catagtagaa agttgggggg aaaatctgtt 800

 tcataaacat ttcctcagca gcagtccagt ctattgcatt ttaattggtt 850

 gtgatatcat tgttttatgc aatacgttct caacaagtat atcctccggc 900

 aaactgaaca aggaccaagt ctgttctgcc tacagctctg cttcctcata 950

 gctgctttcc agaacgtgac tcttgcaaat tatcaagaaa ggggaactaa 1000

 tctaagggat ccagatcaaa cagcctcatg aagacttatt ttatgtttct 1050

 aatataaaga tagaagtttt cagaaaagcc ctgctacaca gaggatcaga 1100

 gcaggggtgg gcctgctggg ctgcagctgg gattctgagc atcctttccc 1150

 ggaggcacgg aaagtgagtg agtgagccca gtgaggaaga agttgaagct 1200

 ttgatatgag taaacaagta tctctacctg aaatgattaa agactggacc 1250

 aaagagcatg tgaaaaaatg ggtaaatgaa gaccttaaga ttaatgagca 1300

 atacgggcaa attctgctca gtgaagaagt aacaggatta gtcctgcagg 1350

 aattaactga gaaggacctt gtagaaatgg ggctaccatg gggtccagca 1400

 cttttgataa aacgttcata caacaaattg aatagtaagt cccctgaaag 1450

 tgacaatcat gatccgggac aattagataa ttcaaaaccg tccaaaacag 1500

 aacaccagaa aaatccaaaa cacaccaaaa aggaagaaga aaattcaatg 1550

 tcatctaata ttgattatga tcccagagag atcagagata tcaaacaaga 1600

 agaatcaatt cttatgaaag aaaatgtgtt agatgaagta gcaaatgcta 1650

 aacacaagaa aaagggtaag ctaaaacctg aacaattgac ttgtatgcca 1700

 tatccttttg atcagttcca tgacagccat cgctacatag aacattatac 1750

 tctacaacct gaaacaggag cactcaatct cattgatcca atacatgagt 1800

 tcaaagctct cacaaacaca gaaacagcca cggaagtgga cattaagatg 1850

 aaattcagca atgaagtctt ccgatttgca tcagcttgta tgaattcacg 1900

 caccaatggc accatccatt ttggagtcaa ggacaaaccc catggagaaa 1950

 ttgttggtgt gaaaatcacc agtaaggctg ccttcattga ccacttcaat 2000

 gtaatgatca aaaagtattt tgaagaaagt gagatcaatg aagccaagaa 2050

 gtgtattcgg gagccaaggt ttgtggaagt ccttctgcag aacaatacac 2100

 catctgacag atttgtcatt gaagttgata ctattccaaa acactctata 2150

 tgtaatgata agtatttcta cattcagatg caaatttgta aagataaaat 2200

 atggaaacaa aaccaaaatc tttcactgtt tgtaagagaa ggggctagct 2250

 ctagggatat cctggccaat tccaagcaac gggatgtaga tttcaaggca 2300

 tttttacaaa atttaaagtc actggtagca tctagaaaag aggctgaaga 2350

 agagtatgga atgaaggcaa tgaagaagga gagtgaagga ctaaagctgg 2400

 ttaaacttct cataggaaac cgagactcac tggataattc atactatgac 2450

 tggtacattc ttgtaacaaa taaatgccat ccaaaccaaa taaagcactt 2500

 agatttttta aaagaaatta aatggtttgc tgtgttggag tttgatcctg 2550

 aatctatgat caatggagtg gtcaaagctt acaaagaaag tcgggtggca 2600

 aaccttcact ttccaaatca atatgaagac aagacaacta acatgtggga 2650

 gaagatttct actcttaatc tttaccaaca gcccagctgg attttctgca 2700

 acggcagatc agacctgaaa agcgagacat ataaacctct agaaccacat 2750

 ttatggcaga gagaaagagc ttcagaagtc aggaaactaa ttttatttct 2800

 cacagatgaa aatataatga caagaggaaa atttttggta gtgtttctat 2850

 tactctcttc agtggaaagc ccaggagatc cactcattga aactttctgg 2900

 gctttctatc aagctctcaa aggaatggaa aatatgttgt gtatctctgt 2950

 aaactcacat atttatcaac gatggaaaga tctactacaa acaagaatga 3000

 agatggaaga tgaactaaca aaccacagta tttccacttt aaatatagaa 3050

 ctggtaaaca gcactatcct taaactaaaa tcggtgactc ggtcatcaag 3100

 aaggtttttg cccgcccgtg gatcttcttc agttatccta gagaaaaaga 3150

 aagaggatgt cttgactgca ctggaaatcc tctgtgaaaa tgagtgtaca 3200

 gagacagaca tcgagaaaga caaatctaaa ttcctggagt ttaagaaatc 3250

 aaaagaagaa cacttttatc gaggtggcaa agtatcctgg tggaacttct 3300

 atttttcttc tgaaaactat tcttcagatt ttgttaaaag ggacagttat 3350

 gaaaagctta aagatttaat acactgctgg gcagagtctc ctaaaccaat 3400

 atttgcaaaa atcatcaatc tttatcatca tccaggctgt ggaggtacca 3450

 cactggctat gcatgttctc tgggacttaa agaaaaactt cagatgtgct 3500

 gtgttaaaaa acaagacaac tgattttgca gaaattgcag agcaagtgat 3550

 caatctggtc acctataggg caaagagcca tcaggattac attcctgtgc 3600

 ttctccttgt ggatgatttt gaagaacaag aaaatgtcta ctttctacaa 3650

 aatgccatcc attccgtttt agcagaaaag gatttgcgat atgaaaaaac 3700

 attggtaatt atcttaaact gcatgagatc ccggaatcca gatgaaagtg 3750

 caaaattggc agacagtatt gcactaaatt accaactttc ttccaaggaa 3800

 caaagagctt ttggtgccaa actgaaggaa attgaaaagc agcacaagaa 3850

 ctgtgaaaac ttttattcct tcatgatcat gaaaagcaat tttgatgaaa 3900

 catatataga aaatgtagtc aggaatatcc taaaaggaca ggatgttgac 3950

 agcaaggaag cacaactcat ttccttcctg gctttactca gctcttatgt 4000

 tactgactct acaatttcag tttcacagtg tgaaatattt ttgggaatca 4050

 tatacactag tacaccctgg gaacctgaaa gcttagaaga caagatggga 4100

 acttattcta cacttctaat aaaaacagaa gttgcagaat atgggagata 4150

 cacaggtgtg cgtatcattc accctctgat tgccctgtac tgtctaaaag 4200

 aactggaaag aagctatcac ttggataaat gtcaaattgc attgaatata 4250

 ttagaagaga atttattcta tgattctgga ataggaagag acaaatttca 4300

 acatgatgtt caaactcttc tgcttacaag acagcgcaag gtgtatggag 4350

 atgaaacaga cactctgttt tccccattaa tggaagcttt acagaataaa 4400

 gacattgaaa aggtcttgag tgcaggaagt agacgattcc cacaaaatgc 4450

 attcatttgt caagccttag caagacattt ctacattaaa gagaaggact 4500

 ttaacacagc tctggactgg gcacgtcagg ccaaaatgaa agcacctaaa 4550

 aattcctata tttcagatac actaggtcaa gtctacaaaa gtgaaatcaa 4600

 atggtggttg gatgggaaca aaaactgtag gagcattact gttaatgacc 4650

 taacacatct cctagaagct gcggaaaaag cctcaagagc tttcaaagaa 4700

 tcccaaaggc aaactgatag taaaaactat gaaaccgaga actggtcacc 4750

 acagaagtcc cagagacgat atgacatgta taacacagct tgtttcttgg 4800

 gtgaaataga agttggtctt tacactatcc agattcttca gctcactccc 4850

 tttttccaca aagaaaatga attatccaaa aaacatatgg tgcaattttt 4900

 atcaggaaag tggaccattc ctcctgatcc cagaaatgaa tgttatttgg 4950

 ctcttagcaa gttcacatcc cacctaaaaa atttacaatc agatctgaaa 5000

 aggtgctttg acttttttat tgattatatg gttcttctga aaatgaggta 5050

 tacccaaaaa gaaattgcag aaatcatgtt aagcaagaaa gtcagtcgtt 5100

 gtttcaggaa atacacagaa cttttctgtc atttggatcc atgtctatta 5150

 caaagtaaag agagtcaatt actccaggag gagaattgca ggaaaaagct 5200

 agaagctctg agagcagata ggtttgctgg actcttggaa tatcttaatc 5250

 caaactacaa agatgctacc accatggaaa gtatagtgaa tgaatatgcc 5300

 ttcctactgc agcaaaactc aaaaaagccc atgacaaatg agaaacaaaa 5350

 ttccattttg gccaacatta ttctgagttg tctaaagccc aactccaagt 5400

 taattcaacc acttaccacg ctaaaaaaac aactccgaga ggtcttgcaa 5450

 tttgtaggac taagtcatca atatccaggt ccttatttct tggcctgcct 5500

 cctgttctgg ccagaaaatc aagagctaga tcaagattcc aaactaatag 5550

 aaaagtatgt ttcatcctta aatagatcct tcaggggaca gtacaagcgc 5600

 atgtgcaggt ccaagcaggc aagcacactt ttctatctgg gcaaaaggaa 5650

 gggtctaaac agtattgttc acaaggccaa aatagagcag tactttgata 5700

 aagcacaaaa tacaaattcc ctctggcaca gtggggatgt gtggaaaaaa 5750

 aatgaagtca aagacctcct gcgtcgtcta actggtcagg ctgaaggcaa 5800

 gctaatctct gtagaatatg gaacagagga aaaaataaaa ataccagtaa 5850

 tatctgttta ttcaggtcca ctcagaagtg gtaggaacat agaaagagtg 5900

 tctttctacc taggattttc cattgaaggc cctctggcat atgatataga 5950

 agtaatttaa gacaatacat cacctgtagt tcaaatacgt ttatttatat 6000

 ctttatgatt ttattctctc tctctattct catggcactt tcataacatt 6050

 atggctaacc tctaattaca gattttgctt ttgcctccct gaatgaatta 6100

 caagcctttt taagatatga aatatgccta cccgcagagc ttggcacaaa 6150

 gtggagtcaa tcttttaatg ttttaaatat gcattttcag actcaaataa 6200

 ttaagaagtt tcattgatat ccactggtca catcataact gtctataggg 6250

 caataaaatc tgtgttaaac tcaattgctt ttataagttt tctaaattat 6300

 ttcttcactg tgacagcaaa gatttaaata agatgaatgt aaaagagaaa 6350

 gcttattgga ctcaaaccca cagatccaca ccagagttct atttacctca 6400

 tcttggtatc aataaaaact tatgtggaag gtaaatatat tgttccccat 6450

 ccaccacata acactctccc caacacacac acacacacac acacacacac 6500

 acacacacac acacactcct tgtacccctt gcccttctcc cagctcattg 6550

 ctccaggaga gagaagagtt caaaaaataa agtaatcata aacttgaact 6600

 ctctccattc tcttgttccc atttacaggt gaatctcttc ctttaagcca 6650

 tttttgtctc ctgtgaatac agccttatct ccacctgttt cttagatccc 6700

 atctcccctg gcttattttt tccattcatt accctctttg ttccctttac 6750

 ttctcaacct gtgctatata catgctgttc tctctgttga gattgcctta 6800

 tttccatcta acattctctc tcctgctatt ctgatttgtc attcacaact 6850

 gatttcaaga gtcaccttca ccaggaagtc ttccttgacc accatcattc 6900

 ctgcctgatt agagggcttc ctcatggtaa tatgtgttct caagttttca 6950

 gtgtcaagga atgccatccc agaagctcat tctcagatgc acaacagcca 7000

 gaacagtctc aagcagcatt ctagagcttg gaatttaaga actacgcatt 7050

 gcctataaag tgaaacatag gctaatatag attaaattga atattgaata 7100

 aaaaatatat ttatttatcc ac 7122

<210> 5011
<211> 810
<212> DNA
<213> Homo sapien

<400> 5011
 aatataaatg acttacatag cattttagat cagtggatgt ttttgtgatt 50

 cttttatttg agctttggcc aaagataaca gtacccacag gttttttcca 100

 gctactcgct cttctccctt cagtggccct cgagcctgga aaatctgaca 150

 tgacaatgtg cttgctcaac ctaccactgt ttttcttttg aaaagtttgg 200

 cagcctgttt ctgactccta tgaaggtgaa ttcctcagca ttcacagttt 250

 attagaaaaa tactttgctt ctctccaaac tcgaaattca agataaccaa 300

 acctatatat aggctgatct ttcaggatgc agttgtcatg ttgatgccat 350

 gcttttcagt atcgtggcca tcatctgttc agtaggggag gtgtacttct 400

 gtaatgggag gtggtggtta tgtgtgtgtg caagtgttta tttggtgtct 450

 taagttagcc tgtgggaagt tctaaatcag gatggtacgt ggttgccagc 500

 agagagctgc tcctcaagtg aaggaggtag aatcaaagcc aataggaaag 550

 agcctcagat gcttatatat gtaccgtggg gattcagagt gaaagcagtc 600

 attggactag gggtggggtt agggagagcc tgtctgacag acacaagaaa 650

 gggatggata acgccaccca gagaaaaaag cattttaggc aagaacaaat 700

 atgaaaaagg aacaaagtct gtgggtgggg agcaaggagg agataagttg 750

 acttgaagga agacaacact tatgaaagtc acctggaggc tgggtgccat 800

 ggctcatgcc 810

<210> 5012
<211> 12
<212> PRT
<213> Homo sapien

<400> 5012
 Met Lys Val Thr Trp Arg Leu Gly Ala Met Ala His
   1               5                  10

<210> 5013
<211> 3362
<212> DNA
<213> Homo sapien

<400> 5013
 gggtgggtag aggtgcgcgc ctgggacctg aacatggact tcccgtgcct 50

 ctggctaggg ctgttgctgc ctttggtagc tgcgctggat ttcaactacc 100

 accgccagga agggatggaa gcgtttttga agactgttgc ccaaaactac 150

 agttctgtca ctcacttaca cagtattggg aaatctgtga aaggtagaaa 200

 cctgtgggtt cttgttgtgg ggcggtttcc aaaggaacac agaattggga 250

 ttccagagtt caaatacgtg gcaaatatgc atggagatga gactgttggg 300

 cgggagctgc tgctccatct gattgactat ctcgtaacca gtgatggcaa 350

 agaccctgaa atcacaaatc tgatcaatag tacccggata cacatcatgc 400

 cttccatgaa cccagatgga tttgaagccg tcaaaaagcc tgactgttac 450

 tacagcatcg gaagggaaaa ttataaccag tatgacttga atcgaaattt 500

 ccccgatgct tttgaatata ataatgtctc aaggcagcct gaaactgtgg 550

 cagtcatgaa gtggctgaaa acagagacgt ttgtcctctc tgcaaacctc 600

 catggtggtg ccctcgtggc cagttaccca tttgataatg gtgttcaagc 650

 aactggggca ttatactccc gaagcttaac gcctgatgat gatgtttttc 700

 aatatcttgc acatacctat gcttcaagaa atcccaacat gaagaaagga 750

 gacgagtgta aaaacaaaat gaactttcct aatggtgtta caaatggata 800

 ctcttggtat ccactccaag gtggaatgca agattacaac tacatctggg 850

 cccagtgttt tgaaattacg ttggagctgt catgctgtaa atatcctcgt 900

 gaggagaagc ttccatcctt ttggaataat aacaaagcct cattaattga 950

 atatataaag caggtgcacc taggtgtaaa gggtcaagtt tttgatcaga 1000

 atggaaatcc attacccaat gtaattgtgg aagtccaaga cagaaaacat 1050

 atctgcccct atagaaccaa caaatatgga gagtattatc tccttctctt 1100

 gcctgggtct tatattataa atgttacagt ccctggacat gatccacaca 1150

 tcacaaaggt gattattccg gagaaatccc agaacttcag tgctcttaaa 1200

 aaggatattc tacttccatt ccaagggcaa ttggattcta tcccagtatc 1250

 aaatccttca tgcccaatga ttcctctata cagaaatttg ccagaccact 1300

 cagctgcaac aaagcctagt ttgttcttat ttttagtgag tcttttgcac 1350

 atattcttca aataaagtaa aatgtgaaac tcaacccaca tcaccacctg 1400

 gaatcaggga ttgctcactc caggttactg caaccctaac tcactctagt 1450

 gggaccttga ctggagaaac tccacgatct tcctgaagaa gagaaatgga 1500

 tgtttccaaa ttccacaata agcaatatgt ggtgataatg aaaagaatga 1550

 ttcagtcttg acggtgaatg gaagacactt acctaacaag tactgctcat 1600

 ttacactcaa attaatcttg aagtagtctt aaaatgtgta agaagttaaa 1650

 acttgagaag caaaaaaatg cctgcaaaaa gaagatcatt ttgtatacag 1700

 agaaccggat gaatataagc aatgaagatg aacatttatt gatcttctac 1750

 atacaagact tcaccataag gccaggagca gtggctcaca ccttgtaatc 1800

 ccagcacttt gggaggccaa ggtgggcgga tcaccttgag gtcaggagtt 1850

 caagaccagc ctgaccaaca tggtgaaacc ctgtctctac taaatattag 1900

 cggggtgtgg tggcgggcac ctgtagtcgc agcctttcgg gaggctgaga 1950

 caggagaatc gcttgaaccc tagaggcgga gtttgcagtg agccgagata 2000

 gtgccattgt actccagctt gggcaacaga gtaagactct gtctcaaaaa 2050

 aaaaaaaaca aaaacaaaca aacaaaaaaa acacctcacc atgagtgcta 2100

 catgtgaata gatattaagt gccatatata attagttctc agaagaaggg 2150

 agaaatgatc ataggactgg gaattgtttt gcaaacgttc taggagatgt 2200

 gagagaaaat atgtaaccac atcttagtgg cccaagaaaa tacaggcctg 2250

 aagggataag attgtgtctc tatagagctt caaagcatac aggtcaatta 2300

 agaaagcccc tctctctcca gagccgtttc cctagctttt ggcacctgga 2350

 tgccacagtc ctccattagg ctgatgactc caaagatgta actctagcct 2400

 cttgcctgag cttcagactc gcgtcccact gcccacagga cacatccacc 2450

 tggatgtgac tcacaggtac ctccaaccca tcatgtggag atactcatcc 2500

 tgttccccct agagctgctc ttcctgctgc attctctctc tcaattactg 2550

 ggaccaccaa gctaggaacc tgggagtcat ccttgatact ttctcttcct 2600

 ccttaatcct gtgtattcag caagtaacta aaggttggtg ttggccaggc 2650

 atggtggctc atgcctgtaa tcccagcatt ttgggaggcc aaggcgggcg 2700

 gatcacttga ggtcaggagc tcaagaccag cctggccaac atggtgaaac 2750

 cccatctcta ctaaaaaaaa aaaaaaaatt agtcgggcgt ggtggtgcat 2800

 gcctgtaatc ccagctactg gggaggctga ggcaggagaa tcgcttgaac 2850

 ctgggaggca gaggttgcag tgagccggga ttgcgccatt gtactccagc 2900

 ctgggtgaag aagtgagact ctgtcttaaa aaaaaaaatt ggtgctgata 2950

 aatattgatg aattctgctc tctgctctct atggttgtca acactgcaga 3000

 gttgaggcct catatctcac ctgcactgct gcaacagctt actggtccct 3050

 tgctcccagc cttctcctct tcagtccatc gtccacacag cactggggaa 3100

 ggggagccac ttgaaacaaa agtcaacaac tggttgtagt tcataaacac 3150

 agagctgttt gtgtcccctg tatctggatt gccattatga cccactacat 3200

 tttttctttt cctacccctc taaaaactca gttcaggtag cagctccact 3250

 aggaagcctt ggctgaccat aatcccattc aattccattt cacctcttcg 3300

 caggcagtct ggggttaggg accctttctc tttgctcccc aaaataaact 3350

 ggttatctct ac 3362

<210> 5014
<211> 443
<212> PRT
<213> Homo sapien

<400> 5014
 Met Asp Phe Pro Cys Leu Trp Leu Gly Leu Leu Leu Pro Leu Val
   1               5                  10                  15

 Ala Ala Leu Asp Phe Asn Tyr His Arg Gln Glu Gly Met Glu Ala
                  20                  25                  30

 Phe Leu Lys Thr Val Ala Gln Asn Tyr Ser Ser Val Thr His Leu
                  35                  40                  45

 His Ser Ile Gly Lys Ser Val Lys Gly Arg Asn Leu Trp Val Leu
                  50                  55                  60

 Val Val Gly Arg Phe Pro Lys Glu His Arg Ile Gly Ile Pro Glu
                  65                  70                  75

 Phe Lys Tyr Val Ala Asn Met His Gly Asp Glu Thr Val Gly Arg
                  80                  85                  90

 Glu Leu Leu Leu His Leu Ile Asp Tyr Leu Val Thr Ser Asp Gly
                  95                 100                 105

 Lys Asp Pro Glu Ile Thr Asn Leu Ile Asn Ser Thr Arg Ile His
                 110                 115                 120

 Ile Met Pro Ser Met Asn Pro Asp Gly Phe Glu Ala Val Lys Lys
                 125                 130                 135

 Pro Asp Cys Tyr Tyr Ser Ile Gly Arg Glu Asn Tyr Asn Gln Tyr
                 140                 145                 150

 Asp Leu Asn Arg Asn Phe Pro Asp Ala Phe Glu Tyr Asn Asn Val
                 155                 160                 165

 Ser Arg Gln Pro Glu Thr Val Ala Val Met Lys Trp Leu Lys Thr
                 170                 175                 180

 Glu Thr Phe Val Leu Ser Ala Asn Leu His Gly Gly Ala Leu Val
                 185                 190                 195

 Ala Ser Tyr Pro Phe Asp Asn Gly Val Gln Ala Thr Gly Ala Leu
                 200                 205                 210

 Tyr Ser Arg Ser Leu Thr Pro Asp Asp Asp Val Phe Gln Tyr Leu
                 215                 220                 225

 Ala His Thr Tyr Ala Ser Arg Asn Pro Asn Met Lys Lys Gly Asp
                 230                 235                 240

 Glu Cys Lys Asn Lys Met Asn Phe Pro Asn Gly Val Thr Asn Gly
                 245                 250                 255

 Tyr Ser Trp Tyr Pro Leu Gln Gly Gly Met Gln Asp Tyr Asn Tyr
                 260                 265                 270

 Ile Trp Ala Gln Cys Phe Glu Ile Thr Leu Glu Leu Ser Cys Cys
                 275                 280                 285

 Lys Tyr Pro Arg Glu Glu Lys Leu Pro Ser Phe Trp Asn Asn Asn
                 290                 295                 300

 Lys Ala Ser Leu Ile Glu Tyr Ile Lys Gln Val His Leu Gly Val
                 305                 310                 315

 Lys Gly Gln Val Phe Asp Gln Asn Gly Asn Pro Leu Pro Asn Val
                 320                 325                 330

 Ile Val Glu Val Gln Asp Arg Lys His Ile Cys Pro Tyr Arg Thr
                 335                 340                 345

 Asn Lys Tyr Gly Glu Tyr Tyr Leu Leu Leu Leu Pro Gly Ser Tyr
                 350                 355                 360

 Ile Ile Asn Val Thr Val Pro Gly His Asp Pro His Ile Thr Lys
                 365                 370                 375

 Val Ile Ile Pro Glu Lys Ser Gln Asn Phe Ser Ala Leu Lys Lys
                 380                 385                 390

 Asp Ile Leu Leu Pro Phe Gln Gly Gln Leu Asp Ser Ile Pro Val
                 395                 400                 405

 Ser Asn Pro Ser Cys Pro Met Ile Pro Leu Tyr Arg Asn Leu Pro
                 410                 415                 420

 Asp His Ser Ala Ala Thr Lys Pro Ser Leu Phe Leu Phe Leu Val
                 425                 430                 435

 Ser Leu Leu His Ile Phe Phe Lys
                 440

<210> 5015
<211> 2067
<212> DNA
<213> Homo sapien

<400> 5015
 gttcattcca agcggaagtg atggctggtg gatatgactt gaggggaatt 50

 cctgagggca aggaaaagga agaaaggggc cccagagaag acgaggcaca 100

 gctggagaac cctagggctg tgaacactgc gactgccgcg cggggcagct 150

 gcgccgtgtt tgctggaagc ctccggtagc tgctgaaacc ttcgctccgg 200

 aggtcgcctc ggtaaacctt gcggatgatt ccaccacggc ggaaagacga 250

 aaaggaggct tctaggcacc cgggaccgcc cgtgtcccgc ccttttcccc 300

 gatgaagtct gacgcggcag gtccctcggc agggttaatg ggacggcctg 350

 gtggggcatt gccggtcttt cccagccaca gacaagcttc gcgcctcgat 400

 cccccagcgc ccccagacgc tggatgccga ggcctggtcc tttacagccg 450

 ccgacgcctc atgagcgaag ccagccagat gccagcaccg ccttcggccc 500

 cgccccgagc cagcccctcc cacatccccg cccggggcac gccctcggcc 550

 cgcccccatc tccgccccga gcacgcccct agattggccc cgccccgtcc 600

 ccgcccgcaa ctccgccccg accggaagaa gccgcggcac ccagcgctta 650

 tagggccggg aatgggggtg ccgccgctgc ctagtcagtt ctgcgtccgc 700

 tgaggctcgg tcaccgcctc gctgtcgtcg cggcgccccc gccccgtcct 750

 ctgtccgtac cgcccccgga gccagggccg agtcctcgcc atgccggccc 800

 ggcggctgct gctgctgctg acgctgctgc tgcccggcct cggggtgagt 850

 gaccggggag cgtggggtgg aggacagctc gcgacggccg ggtcggggcc 900

 ggggcagcgt cgcggcgccg gggctggagt ccgagctggg agcgcgacgg 950

 cggcggccag atgccccgtg agcccagccg tgggaggctc gggccgggcg 1000

 taggaggcgg caccgggccg ggagagcttc cctgacggga gtcgcggccc 1050

 caccgaggcg tcggccgccc gaagagcctc ccaagccagc gcggctgtca 1100

 cgggcagcgg ctccccggac cccgcgggct cgggcgcaac ttcgtggcgt 1150

 cctgcacggc acttgggggt cccagaaggc cccggcctga ggaggccgcc 1200

 cacctgcggg accctcctcc tcgcgggcgg gcgccggcgc tgcctggcgg 1250

 gggccgcgga ggagccgaaa gggcgttggg atccagggga agggtctgtc 1300

 ctgcgcttcg aatccttgtt tgaacttttt aaaaattcga aaactttggg 1350

 gaacgaatgc aacagggagt aaggactctc acccgagagc tggcttctgc 1400

 cacttgccct gccggtttct tggtactggg aggctgcagg cttccttctg 1450

 tgcaccgaga cttccttgag caagtggagc tgtgggaatt gcactcttgg 1500

 aagatcccgc atgggttcga ggtgaggccg cttcagaacc tcaaatgaaa 1550

 gactgtctcc tcgtgggaga gcacctgggg ccatcagaaa tgtcttttca 1600

 tctttttctg gaggagacga atgatagggc ctggtttaca ttcatttaac 1650

 tctttatgac cttcactcag ctgtggattt gggggcactt tgtgggagac 1700

 ttggcttttt tttttcttct ggttggaaga acctaaatta gtgaatgttt 1750

 ttcacaaaat gtattgttca ggatgtgagc gtggcaaatt tgtccgtgtt 1800

 ctgtttaatg acctctttaa aggtactgtg tactctttaa tagggatatc 1850

 atgtaccagg tgtcccagta gagcactgac atgtgtgtgc ctgagtgcca 1900

 gccaccgtgt gaactctttg gaggttttgc attttaggta aataactgtc 1950

 tgtactcttg gagtaacaag aatttggaaa caggagaagt aaataaataa 2000

 ggttgccttt ttcaaattca gggttttttt tttaaataaa ggaaaatttg 2050

 tagactcttt ataatag 2067

<210> 5016
<211> 133
<212> PRT
<213> Homo sapien

<400> 5016
 Met Lys Ser Asp Ala Ala Gly Pro Ser Ala Gly Leu Met Gly Arg
   1               5                  10                  15

 Pro Gly Gly Ala Leu Pro Val Phe Pro Ser His Arg Gln Ala Ser
                  20                  25                  30

 Arg Leu Asp Pro Pro Ala Pro Pro Asp Ala Gly Cys Arg Gly Leu
                  35                  40                  45

 Val Leu Tyr Ser Arg Arg Arg Leu Met Ser Glu Ala Ser Gln Met
                  50                  55                  60

 Pro Ala Pro Pro Ser Ala Pro Pro Arg Ala Ser Pro Ser His Ile
                  65                  70                  75

 Pro Ala Arg Gly Thr Pro Ser Ala Arg Pro His Leu Arg Pro Glu
                  80                  85                  90

 His Ala Pro Arg Leu Ala Pro Pro Arg Pro Arg Pro Gln Leu Arg
                  95                 100                 105

 Pro Asp Arg Lys Lys Pro Arg His Pro Ala Leu Ile Gly Pro Gly
                 110                 115                 120

 Met Gly Val Pro Pro Leu Pro Ser Gln Phe Cys Val Arg
                 125                 130

<210> 5017
<211> 4201
<212> DNA
<213> Homo sapien

<400> 5017
 ggcctgaaaa cctccgcgcc accgctgcgc tctttacaaa ggccccgggc 50

 gcgagaggac gtgctctgcc agccagtggg aaggcaggcc gcgcgcgcgg 100

 gagcgcggga ggatcggcgg ctcgcggtca ctggtccctg gctcggttcc 150

 ccgcaccccg gggctcacac ttacccgcgc ggaggagcag cggccgggtg 200

 tccaccccca tcctgcgccc agtctcctcg attcccctcg ctctgagccg 250

 ggagagccga acagctgaag agagttcact gactccccag ccccaggtgg 300

 gccttgtgca catcatgacc agttttgaag atgctgacac agaagagaca 350

 gtaacttgtc tccagatgac ggtttaccat cctggccagt tgcagtgtgg 400

 aatatttcag tcaataagtt ttaacagaga gaaactccct tccagcgaag 450

 tggtgaaatt tggccgaaat tccaacatct gtcattatac ttttcaggac 500

 aaacaggttt cccgagttca gttttctctg cagctgttta aaaaattcaa 550

 cagctcagtt ctctcctttg aaataaaaaa tatgagtaaa aagaccaatc 600

 tgatcgtgga cagcagagag ctgggctacc taaataaaat ggacctgcca 650

 tacaggtgca tggtcagatt cggagagtat cagtttctga tggagaagga 700

 agatggcgag tcattggaat tttttgagac tcaatttatt ttatctccaa 750

 gatcactctt gcaagaaaac aactggccac cacacaggcc cataccggag 800

 tatggcactt actcgctctg ctcctcccaa agcagttctc cgacagaaat 850

 ggatgaaaat gagtcatgaa cacagaaagt ctaagaggag aaatatgatg 900

 gatgaagagc tctgtagatg ctgtatagac actaaataag agttgattag 950

 ggtagtatat tatagtcatc tgttatgctg tgaaatttgg aattcagtat 1000

 tatcattttg aagtctgtaa attgtgttag tcattaactt agtcacctgt 1050

 tgtattctgg atctacacaa aattatttta actgctctta ttaatctgtg 1100

 aggattaata tacaaaaagt atcctttgag atgaagtcgt gttctcaaaa 1150

 taaggttata ttattttctt tttctgcttg attttcatct tgtgttttgc 1200

 tttgtttttg taaggaacca tctcttggtt tggtcacatc agttcacaac 1250

 agccatttgt tttcaaggtc aaggctccag gcaggttgtt actggtgttt 1300

 gcagcctgtc agtacttgca gtactggaat aggttctagg ctagtgtctg 1350

 cgcgtcactg tggttttagc atgggaggac ttatttgaga aatactacct 1400

 tacttttcta tgatttcttt ttacagagtt atagtgtgtt tactcctaag 1450

 atgacagttc tctttgtcta tattcagcat ctaagacaaa tatttaaaca 1500

 ttttaaagaa ccactgtgtt aagtttagga ttatttactt accaaattag 1550

 aagtttgact tttatgtgtt atacacaatc ttaaaatttc acgaattcac 1600

 ctttttaata gtatccatgt acataataaa atcaaagttt aattagccat 1650

 tttctttgaa tttttttcta aataagggaa ataactgttc ttgggccact 1700

 ttacagagat aaatgtatgt gaatgtttat gataaacgct taaatatttc 1750

 taaaatgtta acttcaaaaa agtctttttc agttcttaaa taaaaattta 1800

 tttatttaag atacttattc gacttatctt aactaaggta gctatgaatg 1850

 ttaagtagat gaggtaacca ttcagttaag ttaaattgta gcattgccag 1900

 gtagtgaggc tcactgtaca attttccagg taaatgaaat ttcctgtagt 1950

 aagaggtccg tatttttgta acagcctttt aaaaatgctt ttgggaaccc 2000

 tccagcctct taccaaaaga ggctttaaac ctcatcttga ttcagactgt 2050

 cagtctattc ctgggcagta gtatgtgatg tccagcaccc taaccccgac 2100

 tccccagccc tgggactatt ccagtagagt gaaatatttg tccctgtaca 2150

 aagtggcctg aatgactgtt ggagttcctg tgtctggttt tcctgtttat 2200

 tccctgtgat gcccagagta atggcccatc caaagatgtc cagatgtcca 2250

 tgtgctagtc tccagaactt gtaactgtgt tgttatgtgg caaaggggaa 2300

 tgaaggctgc agatggaagt aaaatagatt atgctggatt atctgggtgt 2350

 gcccaattga tcaccggatc cgtaaaagtg gaagagaggc agatcaggat 2400

 gtcagcgtga tgaggtgtga gacagacttg acttgctgtt gctgggagga 2450

 aggggaggtc atgagccaag gaatgtggac agtctcttga agctggaaag 2500

 tgtgcattgg acatctggaa gccagaaaag acaaagaaat atccagaaag 2550

 gaacaaagtc ttgtggacac cttgattttg gtccagtgag aatatgtttg 2600

 acttgttaac ctacaaaact ttatgatgat aaatttgtgt tggtcgtaag 2650

 ccactaaatc acagtaattt gttatagcag cagatagaaa actaatatac 2700

 tccctttaat ataaggttat ctactattga ttctttctag gattttagct 2750

 tctggtctga tgtgggttta cagccagatc acccggcttg aattgcttac 2800

 agtgtgtagt ctcatggtaa aggcgttcta tgagtgaagt gtatatactt 2850

 taatgtgtgt atactgtcac attttgacta ttttggaaga ctttcacctc 2900

 tgtttcttgt ctttgaggct gatgaatgtg tttctaagtt ataaatttaa 2950

 tattaaggga ttcatgtatt attgttattg gatccaaaca atgtgttaag 3000

 taatatttag ggccagaaaa atcttgtaca gaataatgat ttctcctaat 3050

 gtaaatcttg gaaagggttt tgttcaactt gagaaatatt aaattttttg 3100

 ttctattttc ttttcttcaa agattggcaa aggagagagt gggttgctaa 3150

 aagtttatat tgttctccaa agaatagaaa cactttccat agcccaactc 3200

 cggtagtaaa taataatgaa cgctttaata atgaaagagc aattggttag 3250

 tattagaatt gttttgatta caaagttagc atctctgcct gagctaccca 3300

 accccaaagc ggggttgtta gaggaaagct accatatttc acagaaccga 3350

 ggaaggaatg cagcagacct caggtgagat tcgaatgctc tggctctgac 3400

 cctcaatgca tattggctcc atggccacct gtagctccca agttttacac 3450

 gttattgatc ccccaaagag accctgatct cttgatttca gttccaggga 3500

 cgggtcagct tgggtcaggt gcccacccct tcaccaatca acttgtctca 3550

 ggtaacgcag tcacattatg taatggctgc tctggtcagt gatcatgtgg 3600

 atagatacag cattttctca aaaaaatggt cacaggggtg ggggtggggc 3650

 aaacaaaaat attggtgttt gatacaaggt actgaagcta agatgtgaaa 3700

 ccttccatat acactttaag gacttctttg tccctggaaa gtgatttttc 3750

 tggggctcct taggtagaga ggtgtattaa tggtgccagt gttagaatcc 3800

 ttggcagtct cttcttgaac ctgcaactcc agtggttaaa tctcataggc 3850

 catataacca ttttctagag aattctgttc ctactatcta atgcagtaac 3900

 tgacttaaaa gtaagtatta ctgttagact ctaacataag tggtggtatt 3950

 tgttttaatg gaggtgggat caggtatgtg ttcacttaag ctttacatta 4000

 aaaaaaaatt tatatgtgta aataaatata tatgccttgt agaaaaatta 4050

 gccataatct tactaccaga agagaactac tgttaacttt gtgtgtgtgt 4100

 atatgtggtg gatggtttta tgttacctcc tggctctttt tatgtttcca 4150

 attctctaac acttgtttaa ttaattactt atattattaa gataaaaaaa 4200

 a 4201

<210> 5018
<211> 288
<212> PRT
<213> Homo sapien

<400> 5018
 Pro Glu Asn Leu Arg Ala Thr Ala Ala Leu Phe Thr Lys Ala Pro
   1               5                  10                  15

 Gly Ala Arg Gly Arg Ala Leu Pro Ala Ser Gly Lys Ala Gly Arg
                  20                  25                  30

 Ala Arg Gly Ser Ala Gly Gly Ser Ala Ala Arg Gly His Trp Ser
                  35                  40                  45

 Leu Ala Arg Phe Pro Ala Pro Arg Gly Ser His Leu Pro Ala Arg
                  50                  55                  60

 Arg Ser Ser Gly Arg Val Ser Thr Pro Ile Leu Arg Pro Val Ser
                  65                  70                  75

 Ser Ile Pro Leu Ala Leu Ser Arg Glu Ser Arg Thr Ala Glu Glu
                  80                  85                  90

 Ser Ser Leu Thr Pro Gln Pro Gln Val Gly Leu Val His Ile Met
                  95                 100                 105

 Thr Ser Phe Glu Asp Ala Asp Thr Glu Glu Thr Val Thr Cys Leu
                 110                 115                 120

 Gln Met Thr Val Tyr His Pro Gly Gln Leu Gln Cys Gly Ile Phe
                 125                 130                 135

 Gln Ser Ile Ser Phe Asn Arg Glu Lys Leu Pro Ser Ser Glu Val
                 140                 145                 150

 Val Lys Phe Gly Arg Asn Ser Asn Ile Cys His Tyr Thr Phe Gln
                 155                 160                 165

 Asp Lys Gln Val Ser Arg Val Gln Phe Ser Leu Gln Leu Phe Lys
                 170                 175                 180

 Lys Phe Asn Ser Ser Val Leu Ser Phe Glu Ile Lys Asn Met Ser
                 185                 190                 195

 Lys Lys Thr Asn Leu Ile Val Asp Ser Arg Glu Leu Gly Tyr Leu
                 200                 205                 210

 Asn Lys Met Asp Leu Pro Tyr Arg Cys Met Val Arg Phe Gly Glu
                 215                 220                 225

 Tyr Gln Phe Leu Met Glu Lys Glu Asp Gly Glu Ser Leu Glu Phe
                 230                 235                 240

 Phe Glu Thr Gln Phe Ile Leu Ser Pro Arg Ser Leu Leu Gln Glu
                 245                 250                 255

 Asn Asn Trp Pro Pro His Arg Pro Ile Pro Glu Tyr Gly Thr Tyr
                 260                 265                 270

 Ser Leu Cys Ser Ser Gln Ser Ser Ser Pro Thr Glu Met Asp Glu
                 275                 280                 285

 Asn Glu Ser


<210> 5019
<211> 3838
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3608-3632
<223> Unknown base

<400> 5019
 tactaaaatg tagccccaaa atgacgggcc agcctcagcg tatctgccat 50

 atgtatttca aagattacag tcagaatgag ttaatgaaaa tggcaggttc 100

 cttttcaaag tttatttgac tcacagccat attgctaagt ttgggtatag 150

 tgaagttaac aacaatcact taaattaata tcttacagca agatatactg 200

 atactgtttt aaatgaaaaa gactgtaaat tcaatgtaaa tattacctaa 250

 ctttatgtac caagttagga gagtggaaga ggggaatttt tcaaaaaata 300

 agctgtattt gaacaaagca tgaaacttgt tgttttaaaa tttaagaata 350

 attgaattta ccatctaatt ggcatccgta ctgtgcattg atagtaatat 400

 ccaaatcatc ttattcttcc atagaggaag cgctcatata aatcacattg 450

 ctgagaacta tataaaacta catagaggta aatggtgctt attaaatatg 500

 agtatagttt gttacttgct ggaagtcttc tagttcattt ggaccatttt 550

 cttaccctga ggtgaactca atatctgttg gcaatgggtg gttaaatgtg 600

 aagtgccctt gttcagtgtc ccttgttctt gtacaggtat tttcttagtt 650

 taaaaaaaaa attctagcat gccaacattt gtctttggcc tattcctttt 700

 tttctgaagt gtgtaacttc tgattttttc tttgctatgt tgtaaataac 750

 agtagctaaa ttctctgttt tactatctac ttttcttttc ttcccagatc 800

 atttcattct aaaattaaat tgcttggttt tctttagagg aaattgctac 850

 atggtatact tgtagtagtg attcatatta aaaaaatagc tggtaaatct 900

 ttctaggtag taacttatcc aaacaatact ttgagtatca tattttgtga 950

 atgacttgct taaactggga aactgaatat tctttttaaa tcatataatt 1000

 cctgtattaa atgtgaaaca cacagtctcc aaagtcacct gattctctgt 1050

 ggaaaatgaa aggcattgaa ggaaaccaga tacattaata cttagttttg 1100

 gttgaaagtg caacattact gtacttagaa ggggcttggt ttatttttag 1150

 atatttaagc tatcattaat tttagaccaa tggctaataa taagagagat 1200

 ttttggttgc tcatttatgg agagacaaag aacagcatgg cataaacaaa 1250

 catcccagaa ataaatgaaa agttttaagt gataaaattg tgttttctat 1300

 gaaccagtgt tgtacatgaa ccaacattgt gtttcttagc tctgacctgt 1350

 acagtgaggt acctgtcagg acccctagtc ttggcactgg aaatgacaaa 1400

 gttctcctat tactaaattc tcatgccttc cttttctgac ttagtagatt 1450

 gaaattggta ggtactaatg atttatgttt gataaactta agttctgctg 1500

 atatcctgtt actggtaatt ctggtaccaa aatttcaaac ggtttgatta 1550

 ttagtagcat tttgagtacc taggtgcata taatacagtt agcagaccct 1600

 tacagagtca aaagagattt tggaatctgg tgatactgtt gtttattaca 1650

 ctagcctatt acattttctt tctttataat aactgtttat gtgagtttca 1700

 ttgaaaatcg tggctctatt gctttattca tggtttccac aactcttttg 1750

 taacacctta attttctctc ttaggtattt tcctgttaaa taagatatca 1800

 aaagcatcaa tcacaagaca gagaaaacgt attaggaaaa acttgtatta 1850

 gtatattcta aactgaaatg gaaaaactca ttattcatat tttaataaat 1900

 aaaactccca aatgatcttg ctaaattatc ccactattta gaagtagaaa 1950

 ataagagaag agtgctttca aggaaatttg tcatattctg ccttctatct 2000

 agaagttgac aatgaattgc aataaaacta agaaataact gaatgctgaa 2050

 aaataccatg aattaatgtt atggcttctt tatttttgta tatccattcc 2100

 cacaaaattg aatttaagat tattaatgaa aattctatat taagtaataa 2150

 tgcttgtatt agtaatgggc aaagaagtct ttctttgtta cattaaccgt 2200

 tagtaaaaga tgtactttga catttctgat gtaaaaccta tatgtaaata 2250

 ttgtaattta aatatgattg gacagctgtt aagttttggg gagggaagca 2300

 gatgccagcg ttctctgctg aaaagacaag atggcgcttg acggaccaca 2350

 gcagatggag ctggaggagg aaaaggcagg cagtggactc tgccagtatt 2400

 atctgtccaa gattgaagaa ctccagggtc aactgcaata taaattggat 2450

 gggggaaagc cacaaggaac agttctgaac tccaggtgca tttgcagctg 2500

 attttgaatg ataagaccca aaacctctgg aggcggcagg tgcacgggaa 2550

 tgaactaaat gttaaagtgt gcctattaca ggaggagcta cagctgctgc 2600

 aggaatagga ctcctgtgtc agggaagtag tccaggccat gggtaagaag 2650

 aaagtgttgg tcaaggtgca tctcaaggac aagtttgtca tagatgtgga 2700

 caaaaatatc agcatcagtg atgtgacacc cagttccttg gtggttctaa 2750

 gaaatgacag ctacactttg cacaagatcc tacccaacaa ggtggactca 2800

 ttggtgtcac tgatgatggt gaagaaagta ccagattcag cttatgaaat 2850

 gattggtaga ctggataggc agatcaagaa gatcaaagaa gtgatcgacc 2900

 tgcctgctaa gcatcccgag ctcttcaaag cactgggcat tgcacagccc 2950

 aagggaatgc tgcttggaag agactgttgg cctgggctct ggctcatcat 3000

 agggactgtg tacctttatt catgtctctg gctctgaatt ggtacagaaa 3050

 ttcattgggg aatttctgtg atggcagaga aaatgctcat ctgtcatctt 3100

 catggatgaa attgactctt ttggctcctc agagctggag ggggatgctg 3150

 gagggaacag tgaagtgcag cagatgatgc ttcgagggtg gctttgaggc 3200

 caccaagagt atcacggttt atcacggctg ctaatacgat tgatatcctg 3250

 gactcggcac tgctttgccc agggcacatt gacagaaaaa ttgaattccc 3300

 aacctgcaat gagtaggcct ggctggtcac tttgaagatt cattctcaga 3350

 aatgaacctg acccagggga tcaacctgag aaaaattgct gagcttatgc 3400

 caggagcatc aggctgaagt gaagggcatg tgcacagaaa ccggcatgta 3450

 tgccctgagt agcgagtcca tgtcactcag aaggactttg aggtagtcca 3500

 aagtcctatc tcatgccaaa ggacagtgag gaaaaacatg tccatcaaga 3550

 aactatggaa ttgagggcac atcctttgtg tgtatcccta caataaaact 3600

 cagtgggnnn nnnnnnnnnn nnnnnnnnnn nngttttggg gagggatgat 3650

 ctgctagtgt ataatcaata acttttaaca tttagcttgt atttagtaac 3700

 atttcattgt gttttgaaaa aaagtaaaaa atcttttgaa gcacattttc 3750

 atgatgtaaa aggtattgag tttcctagtg taagaacatg atttctggaa 3800

 acagtcttag ggacctgggc agatagagcc tccacccc 3838

<210> 5020
<211> 132
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3608-3632
<223> Unknown amino acid

<400> 5020
 Met Gly Lys Lys Lys Val Leu Val Lys Val His Leu Lys Asp Lys
   1               5                  10                  15

 Phe Val Ile Asp Val Asp Lys Asn Ile Ser Ile Ser Asp Val Thr
                  20                  25                  30

 Pro Ser Ser Leu Val Val Leu Arg Asn Asp Ser Tyr Thr Leu His
                  35                  40                  45

 Lys Ile Leu Pro Asn Lys Val Asp Ser Leu Val Ser Leu Met Met
                  50                  55                  60

 Val Lys Lys Val Pro Asp Ser Ala Tyr Glu Met Ile Gly Arg Leu
                  65                  70                  75

 Asp Arg Gln Ile Lys Lys Ile Lys Glu Val Ile Asp Leu Pro Ala
                  80                  85                  90

 Lys His Pro Glu Leu Phe Lys Ala Leu Gly Ile Ala Gln Pro Lys
                  95                 100                 105

 Gly Met Leu Leu Gly Arg Asp Cys Trp Pro Gly Leu Trp Leu Ile
                 110                 115                 120

 Ile Gly Thr Val Tyr Leu Tyr Ser Cys Leu Trp Leu
                 125                 130

<210> 5021
<211> 964
<212> DNA
<213> Homo sapien

<400> 5021
 taaataaata aaatttacaa aattttaaaa atcaaatgaa atatgtcagg 50

 tttgtaccta ccacatttaa actagggact tgaagaatta aacattttat 100

 tacaaatgaa gcacttcatg cacagactgg cacatagtaa gtagtcgata 150

 ggtgttaaca atttgtgtta ttgttatttt ctggagtcca actaacaaat 200

 cccacagtga atgacatcac agggatgcaa ccaacaagat ccagaatatg 250

 gaaacttcta ctagataaac aactccattt cttcagcaac aattcaagag 300

 agagagagaa gagaagctat acattttaaa aggctgaaga aatatatgaa 350

 ccaaatttgt atgaggcaat cagaaaaact gacaccgact gtattaagga 400

 attatctaat tttagtgtgg taatgagatt gctgttatgt tttctaaaaa 450

 gtcattatac tttagatttt cataataaaa taattatgaa tgaagtatgg 500

 tatctgaaag tatcttcaga ataacccagt gtgcatgtat gattaattgg 550

 gtgggtttac aaaattgccc atgaattgat cattgttaaa gcttggctgt 600

 taaaacatgg cactcttctc tctaatactg ttgaagtttt ctgtaataca 650

 aagtttttca aaaaatgcat tccaggaaag tcccataaac ataggcagag 700

 aaacattctg tttgaagtta tgttagtttt taggcttttc tcatttttat 750

 cacagttagg aaatcctaag tatccaaatc ctgcctaagg ctataggaac 800

 ctctcaaaaa tgcaactcta aagaatgtgt atgcaagaac taataatagc 850

 aaaggaaagc aaagtacttt ttcctttatt attggctgta ctaagccccc 900

 agacttgttt atatattcct taattcatca aaactgcaaa aatggtcttt 950

 gagtaccatt atag 964

<210> 5022
<211> 7
<212> PRT
<213> Homo sapien

<400> 5022
 Met Val Phe Glu Tyr His Tyr
   1               5

<210> 5023
<211> 769
<212> DNA
<213> Homo sapien

<400> 5023
 ccatcttagc aggagatccc tttgaactag aatgccctgt gaaatactgt 50

 gctaacaggc ctcatgtgac ttggtgcaag ctcaatggaa caacatgtgt 100

 aaaacttgaa gatagacaaa caagttggaa ggaagagaag aacatttcat 150

 ttttcattct acattttgaa ccagtgcttc ctaatgacaa tgggtcatac 200

 cgctgttctg caaattttca gtctaatctc attgaaagcc actcaacaac 250

 tctttatgtg acaggaaagc aaaatgaact ctctgacaca gcaggaaggg 300

 aaattaacct ggttgatgct caccttaaga gtgagcaaac agaagcaagc 350

 accaggcaaa attcccaagt actgctatca gaaactggaa tttatgataa 400

 tgaccctgac ctttgtttca ggatgcagga agggtctgaa gtttattcta 450

 atccatgcct ggaagaaaac aaaccaggca ttgtttatgc ttccctgaac 500

 cattctgtca ttggactgaa ctcaagactg gcaagaaatg taaaagaagc 550

 accaacagaa tatgcatcca tatgtgtgag gagttaagtc tgtttctgac 600

 tccaacaggg accactgaat gatcagcatg ttgacatcat tgtctgggct 650

 caacaggatg tcaaataata tttctcaatt tgagaatttt tactttagaa 700

 atgttcatgt tagtgcttgg gtcttaaggg tccataggat aaatgattaa 750

 aatttctctc agaaactta 769

<210> 5024
<211> 194
<212> PRT
<213> Homo sapien

<400> 5024
 Ile Leu Ala Gly Asp Pro Phe Glu Leu Glu Cys Pro Val Lys Tyr
   1               5                  10                  15

 Cys Ala Asn Arg Pro His Val Thr Trp Cys Lys Leu Asn Gly Thr
                  20                  25                  30

 Thr Cys Val Lys Leu Glu Asp Arg Gln Thr Ser Trp Lys Glu Glu
                  35                  40                  45

 Lys Asn Ile Ser Phe Phe Ile Leu His Phe Glu Pro Val Leu Pro
                  50                  55                  60

 Asn Asp Asn Gly Ser Tyr Arg Cys Ser Ala Asn Phe Gln Ser Asn
                  65                  70                  75

 Leu Ile Glu Ser His Ser Thr Thr Leu Tyr Val Thr Gly Lys Gln
                  80                  85                  90

 Asn Glu Leu Ser Asp Thr Ala Gly Arg Glu Ile Asn Leu Val Asp
                  95                 100                 105

 Ala His Leu Lys Ser Glu Gln Thr Glu Ala Ser Thr Arg Gln Asn
                 110                 115                 120

 Ser Gln Val Leu Leu Ser Glu Thr Gly Ile Tyr Asp Asn Asp Pro
                 125                 130                 135

 Asp Leu Cys Phe Arg Met Gln Glu Gly Ser Glu Val Tyr Ser Asn
                 140                 145                 150

 Pro Cys Leu Glu Glu Asn Lys Pro Gly Ile Val Tyr Ala Ser Leu
                 155                 160                 165

 Asn His Ser Val Ile Gly Leu Asn Ser Arg Leu Ala Arg Asn Val
                 170                 175                 180

 Lys Glu Ala Pro Thr Glu Tyr Ala Ser Ile Cys Val Arg Ser
                 185                 190

<210> 5025
<211> 3480
<212> DNA
<213> Homo sapien

<400> 5025
 gtgcaaataa ggtttctgtg gtgagacacc agataaactc aacttcctct 50

 ttcaacaaca aatgtgtcag ttatcagcag gatccatgcc gccagagtaa 100

 agctttctac cctttactcc ctgcaaagaa acaagagtgc ttatcccagc 150

 taagctccag ggtaatgtta tcatgacagc ttcaactttt agaccacagg 200

 caaatgcttt gttaaaactc tatgctggtc attcccttca ggatttggca 250

 ctcaccaaca tacccttctt tcaagtgaaa aggcatctct tttaatggtc 300

 ctgacctttg gaataggaag catgtaccct ggacagagca cttcaaacta 350

 gaggaaccat aaatccatgg ctaaccttga caaatacact gaaacattca 400

 agatgggtag caacagtacc agcactgctg agatttactg taatgtcact 450

 aatgtgaaat ttcaatactc cctctatgca accacctata tcctcatatt 500

 cattcctggt cttctggcta acagtgcagc cttgtgggtt ctgtgccgct 550

 tcatcagcaa gaaaaataaa gccatcattt tcatgatcaa cctctctgtg 600

 gctgaccttg ctcatgtatt atctttaccc ctccggattt actattacat 650

 cagccaccac tggcctttcc agagagccct ttgcctgctc tgcttctacc 700

 tgaagtatct caacatgtat gccagcattt gtttcctgac gtgcatcagt 750

 cttcaaaggt gcttttttct cctcaagccc ttcagggcca gagactggaa 800

 gcgtaggtac gatgtgggca tcagtgctgc catctggatc gttgtgggga 850

 ctgcctgttt gccatttccc atcctgagaa gcacagactt aaacaacaac 900

 aagtcctgct ttgctgatct tggatacaag caaatgaatg cagttgcgtt 950

 ggtcgggatg attacagttg ctgagcttgc aggatttgtg atcccagtga 1000

 tcatcatcgc atggtgtacc tggaaaacta ctatatcctt gagacagcca 1050

 ccaatggctt tccaagggat cagtgagagg cagaaagcac tgcggatggt 1100

 gttcatgtgt gctgcagtct tcttcatctg cttcactccc tatcatatta 1150

 actttatttt ttacaccatg gtaaaggaaa ccatcattag cagttgtccc 1200

 gttgtccgaa tcgcactgta tttccaccct ttttgcctgt gccttgcaag 1250

 tctctgctgc cttttggatc caattcttta ttactttatg gcttcagagt 1300

 ttcgtgacca actatcccgc catggcagtt ctgtgacccg ctcccgcctc 1350

 atgagcaagg agagtggttc atcaatgatt ggctaaaatt aagatatctc 1400

 tttaattacg cctttgttta cctacgttcc ttgtcttttt ccaaaggcca 1450

 gaattgtcaa ccaatttctt taattgaaca ttgtaaaaaa caggaataag 1500

 tacttttgtg taatattcac agtcaacagg ggtgtgatgg tgaaggcaga 1550

 gtgtgaaaaa cgtgagagag gaagagaaaa tagatttacc tgattcctct 1600

 ttaaaattca agccactttc ttatttaaga aacctagatc aagtttttac 1650

 agatgtaaat aaaagttgaa tagtttacct taaatttttt tcaataagta 1700

 agttattgtt aataatgcac agtaaatatg tgaatttttc ctagatgtaa 1750

 aaaaaaaaaa tctttcatat aaagacctta aattctgagt gagagtaaaa 1800

 atgtctaatc tttctaacag gtaaattttt ctaacaggca agacagtgtg 1850

 aagaattgaa gcaatatgtg cataaatttc aggaccacaa gcctgttatt 1900

 aaagaaaagg catggaaatt cattcattcc ttgaaaatgt gttgagtgcc 1950

 tattgtgttc ttggttgtca ctttgttagg tactttcttt ttttttcata 2000

 agttattggg gtacaggtgg tatttggtta catgagtaag ttctttagtg 2050

 gtgatttgtg agattttggt gcagccatca cccgagcagt atacactgca 2100

 ccacatttgt agtcttctat ccctcgcccc cttcccactc ttccacacat 2150

 aacatctcat cttgccctcc taataaacct gtggaagttg ccgatacaaa 2200

 tgaataaatg gaacttcaga gaggttaagc aatttgcctc aggatcaaca 2250

 gtggttagcc aaaattggtc cagtataata caccatatat gcttatgtta 2300

 ttcccttgct tttgttgtta catttattag gtctatacta aattagcctt 2350

 caatgatgaa gacagactaa agctaagcca catgagatca aggccatttc 2400

 aacatggttt gcctggaatt ctccaaaaaa cctgtgggtt gtgggtttgg 2450

 catgtcaagc ttcagaccac aaggtcttaa gtggtaaata gatgcgttgt 2500

 cctaatactg ttccaaggta gagaatcctg atgataagga gtataggaaa 2550

 ctcaaatagt tcattatttc taaaaaatgt atattttaag gcatgataca 2600

 agtcctacaa acctcataag taggtgaaaa aaaaaaccct gtggagtgat 2650

 aaacattcta taaaacctgg aaatttgtgt ggagttcgcc taagctcact 2700

 tttcctaaat atagctatat aatattgtaa acaaatttgt tttttagaaa 2750

 cttttaagaa gatttctgtg agcgtaattg acaatatctg cattagaaac 2800

 agaaagtatt atccatcata aatatgagaa aagtgtgtgt cctctttctg 2850

 acaatctttt tatcttattt ttttcaaacg ttgtggttgt tgtttcagca 2900

 ccattttaaa gaatttgaat acaaacaatc cctcagctta tcaggttgac 2950

 atttatgaag ctgacctcat cactctttat cttttatgtc tgcagtataa 3000

 atagcataga catttggtgt gaagggagga gaaaggaagt agtagttctg 3050

 agaatattca tttgaacaga gtgactatgg aagaatgaat agcaaaaaaa 3100

 ggagaatttt tttaaaaaga tctctcactg ggaaaagaaa aagttatgca 3150

 tttataaagt aattaaactg gttttccttg tactttatta atctgaatct 3200

 aatggcactt ccttacgagg gttttcagat gtgcttgtag ttaatggcaa 3250

 cattatcaga atgactacac agacagtcct actctgagga gatgactttg 3300

 gaagaaaccc atttggaact acacaccctg ctatgtctgt ggagaaatgg 3350

 aactgcaatc ctcaagagtc acacttcata ttccttcctt tcaagtggtt 3400

 gataaaaggt agtgcttcaa gcacaggatt tatggaatag ttggcaaatt 3450

 aaacaacatg ctttttattt tgactaccat 3480

<210> 5026
<211> 339
<212> PRT
<213> Homo sapien

<400> 5026
 Met Ala Asn Leu Asp Lys Tyr Thr Glu Thr Phe Lys Met Gly Ser
   1               5                  10                  15

 Asn Ser Thr Ser Thr Ala Glu Ile Tyr Cys Asn Val Thr Asn Val
                  20                  25                  30

 Lys Phe Gln Tyr Ser Leu Tyr Ala Thr Thr Tyr Ile Leu Ile Phe
                  35                  40                  45

 Ile Pro Gly Leu Leu Ala Asn Ser Ala Ala Leu Trp Val Leu Cys
                  50                  55                  60

 Arg Phe Ile Ser Lys Lys Asn Lys Ala Ile Ile Phe Met Ile Asn
                  65                  70                  75

 Leu Ser Val Ala Asp Leu Ala His Val Leu Ser Leu Pro Leu Arg
                  80                  85                  90

 Ile Tyr Tyr Tyr Ile Ser His His Trp Pro Phe Gln Arg Ala Leu
                  95                 100                 105

 Cys Leu Leu Cys Phe Tyr Leu Lys Tyr Leu Asn Met Tyr Ala Ser
                 110                 115                 120

 Ile Cys Phe Leu Thr Cys Ile Ser Leu Gln Arg Cys Phe Phe Leu
                 125                 130                 135

 Leu Lys Pro Phe Arg Ala Arg Asp Trp Lys Arg Arg Tyr Asp Val
                 140                 145                 150

 Gly Ile Ser Ala Ala Ile Trp Ile Val Val Gly Thr Ala Cys Leu
                 155                 160                 165

 Pro Phe Pro Ile Leu Arg Ser Thr Asp Leu Asn Asn Asn Lys Ser
                 170                 175                 180

 Cys Phe Ala Asp Leu Gly Tyr Lys Gln Met Asn Ala Val Ala Leu
                 185                 190                 195

 Val Gly Met Ile Thr Val Ala Glu Leu Ala Gly Phe Val Ile Pro
                 200                 205                 210

 Val Ile Ile Ile Ala Trp Cys Thr Trp Lys Thr Thr Ile Ser Leu
                 215                 220                 225

 Arg Gln Pro Pro Met Ala Phe Gln Gly Ile Ser Glu Arg Gln Lys
                 230                 235                 240

 Ala Leu Arg Met Val Phe Met Cys Ala Ala Val Phe Phe Ile Cys
                 245                 250                 255

 Phe Thr Pro Tyr His Ile Asn Phe Ile Phe Tyr Thr Met Val Lys
                 260                 265                 270

 Glu Thr Ile Ile Ser Ser Cys Pro Val Val Arg Ile Ala Leu Tyr
                 275                 280                 285

 Phe His Pro Phe Cys Leu Cys Leu Ala Ser Leu Cys Cys Leu Leu
                 290                 295                 300

 Asp Pro Ile Leu Tyr Tyr Phe Met Ala Ser Glu Phe Arg Asp Gln
                 305                 310                 315

 Leu Ser Arg His Gly Ser Ser Val Thr Arg Ser Arg Leu Met Ser
                 320                 325                 330

 Lys Glu Ser Gly Ser Ser Met Ile Gly
                 335

<210> 5027
<211> 3170
<212> DNA
<213> Homo sapien

<400> 5027
 cgaggagcgg ggccaccgcg acgttgcagg gtacctgcgc acagccacgg 50

 gggactgacg ccaggttccc cagccgccca caacgacttt attttcttac 100

 ccaatttccc acccccaccc acctaattcg atgaaggctg ccaacgggga 150

 gcggcggaaa gcctgtaagc ctgcaagcct gtctgagact cacaggaagg 200

 aggagccgac cgggaataac cttccataca tttttttctt tgtcttatct 250

 ggccctcgac actcaccatg aagcgaaaca cagagaagcg gatttccagg 300

 gatatttagg agtgtgtgac attccagggg tcgtttgctt ttcagggttt 350

 tctgagggaa agtgcatatg aaatccttga ctggacctgg tggctacgaa 400

 tcttccgatg gatgaatctc ccactccagc gctgagtggg agaaggcagt 450

 gattagcact tgggtgacgg cagtcgatgc gttcactcca atgtctgctg 500

 aggagttatg gtgaacccac aacttaggcc ctagcggcag aaaggaaaac 550

 ctgaagactg aggacaaagt ggaggagggc cgaggtgggc ttcagtaagt 600

 ccccggcggc gctttagttt gagcgcatgg caagtcacat gcgtaaacga 650

 cactctctgg aagccctgga gaccctcgcc caactccacc agatagcaga 700

 ggggtaagag aggatgtgca agcgacgaca gatgctaaaa tccctggatc 750

 acgacgctgc agagcacctt tgcacaggat gctggccttt gctcttacta 800

 cactgaggag agattcccgc gggttccgca ggcagactac acaggatgag 850

 gtggtggagt ggagtgagag caattgtaac ggttaactgt aacgttttct 900

 ttcacacaca cacacacaca cacacacaca cacatgctag gatgcggaaa 950

 tccccttatg acttgctact ttttgatttt gtgatatttt gtacttttta 1000

 gttgttcagc aactgtctta tttaatgggg agattttaag taacataact 1050

 agtggctctc agttaaaatg tgaggaagaa ctacagctct taaatgtagc 1100

 aatggcactg ttgcaaactc agtgcaaacg cctagattgc tttcttctta 1150

 acctatttat ttctttgtta aatttttctg attgtttcct ttatagagtg 1200

 tctcagggtg cagaggtcag actaagaaat attccaaatg tcttttagaa 1250

 gatagatgca cttatgcagt aaattatctt gggatagttc ccaaaagatt 1300

 gctgaaaaag tagattgagt ataaaaactt gaaaatatat gatggctcgt 1350

 gggatgtcct actatcactg aacaaactaa aggtgcactg ctttgggatt 1400

 taatttccag ggttgcttga tcattatatc attggaacaa ctgatacttc 1450

 actactttaa taaagaatta acagagattg aactccaaga ggtgggtaat 1500

 ttggtttaaa aatacatgtt catgggttta ccactaactc ctgagaaatg 1550

 ttaaaggttc acaggggttc ccttctctca atgtttgtaa taattgctca 1600

 taagcaatac cagcaattca taaaaactgc ttacttatgc catagaaaat 1650

 taaacacaaa gtgtatacat gtattatgct tctaaatgct cattctacca 1700

 gatacacatt taaaagagaa aaaaggaaca gaaacaagtc atttgagagt 1750

 ggagacttat aagaaggagt acatttgagt tgaatacaca aatctttact 1800

 tctctaccaa ttcctattcc caaaatgaac atattactgg ggaaagttag 1850

 ttgagaatca gagcatatgt tattggggaa aggatatgtt tattgacaca 1900

 taatctgtac caggtatgca ttaaaatata tttgttaatt taatatttaa 1950

 acctgagaga taggtattgt ttcccagatg aggacaatga ggcaaagaaa 2000

 tatcaagtaa cttgccaaag gttacaagat attcattcca tggatgcaca 2050

 aagaagtgca tctagttcca cagctgatta tggttgtctt gcttttcttc 2100

 ccattgcacc agcttgtcct ccaaaatcat gaatgataca catgaagata 2150

 acttttttta aaaaaaagca gaaatacaca atgatctccc ttgtaagctc 2200

 ctaaggtggc ttttctttct ctaacttcta gtaaatataa acggtttgtt 2250

 tgaaaactat tttaaaatgt caacaatatg gagaataacc ccccccaaca 2300

 cacctataaa aacccaaatt tttggaacaa agataatgga acctccattt 2350

 tcaaactgaa gcacagggac agaaaatata tttctagtta tcacttaagc 2400

 actcaatcat tagaggctac aagaataata tttttaaagt tacagtattt 2450

 tacaattatt agaaaacatt ctatataaaa gaagtcagtt gatactttaa 2500

 aatctcccat ttggtttata aaatccctta atttgacctc tatatcttaa 2550

 attccaagat gtttaaattt gctagttgca ttatactggg tcatgaaaaa 2600

 ttatcccttg aaatagatat gaaacatgtt acttcatttc tggtttaaat 2650

 aacttgtgga atctttccta atgacaacct gatattaagg gaaactaaag 2700

 aaaatgttat tgtggatccc acagtactat attacactgt tttttttgtt 2750

 tgttttgtta gtttttttta tttaaagcaa acctcaaaca ttattgggta 2800

 tcaattacca cctggttgta ttgaaatagt aacttatcaa tgccatgtaa 2850

 aaattaattc cattttcgaa gccacctggc agacaggttt agctgtttca 2900

 tcagcagcct aatatatact gttaaatttg ttaaggattt cactttgaag 2950

 gatacatgca aaacatatag ttactatttt catgagtcct gcttctagct 3000

 ccattgtgga atacagaaaa ttaaatatac ctgttaagtt cgtatctaaa 3050

 cctaagacat taccaaggtt tgtacaaatt ctactacctg acatttattc 3100

 caagaagatc tggaaagtta aataaattta taaatttaaa aaaaaaaaaa 3150

 aaaaaaaaaa aaaaaaaaaa 3170

<210> 5028
<211> 3722
<212> DNA
<213> Homo sapien

<400> 5028
 ggaactagtc tcgagttttt tttttttttt tttgcaattt taagctcatc 50

 agctatcact agtgttagca tattttatag tgtggcccaa gacaattatt 100

 ttcctaatgt ggtccaggga agccaaaaga ttggacaccc tgatatactt 150

 aattaccagg gtaatattcc taacaccatc acttttactt gacaattctc 200

 ctgctctaaa agttatgaac ctgacattct tggtcttaca caatctggac 250

 ccagtctact cttctataac catcttccac ttaatttaca aatctttatt 300

 aaggcacagg tactcctact tatcccctat tgcctctctc atgctgaatc 350

 aatcatgcca aaagctaaga aaacatgagc atgcttggga ctaaagaaac 400

 agaactgagg atttcctaca catcctaact gcaaggacag tccatcaaaa 450

 gccagagata agtattttta tttgctcttt atttcttaaa ataatttccc 500

 caattttgtt aacccctacc tcaaatgact ttagaggtat tttaaaggat 550

 atgtaatata gttactaagc atttccactg attgtagctg aaggattttc 600

 taatgtctat tacatgaaac ttctccttaa actctctttt aacgaaactg 650

 tcattttcct ctccagaacg gtcttgtctt ttctttctcc tatatatcgc 700

 atataaaatc agcggccaaa tcttctagat caaacatatt catttcatcc 750

 attccttcaa ttatccagtc attcaatcaa cattattatg tgtaaagtat 800

 gacccacttg cattcctaga catggaagat ccaaaattaa tgtgaataat 850

 aatctagtga aaagataagc atggacaaaa gtaattatta gacaaaattg 900

 atgctataat aaatgaacat tggaagggct atggttaagt gattaagctt 950

 gacttggatc tctaaaggtg aatggttctt taccaggcta agaagaaaag 1000

 gaaacattct aggaaaagag aacagcaagc atgaaaacca taaaagggct 1050

 gccgcagaag ttcctcttcc tcctcttcct ctcgggcctg gtcaccctgt 1100

 gcttcggggc cctcttcctg ctgccccact cctctcgcct caagcgcctc 1150

 ttcctggccc cccggaccca gcagcctggt ctggaagtgg tggctgaaat 1200

 cgccggccat gccccggccc gcgagcagga gccgcctccc aacccggccc 1250

 ccgccgcgcc ggccccgggc gaggatgacc ccagcagctg ggccagtccc 1300

 cgccgcagga aaggggggct gcggcgcacc cgccccactg gaccccgcga 1350

 ggaggccacg gcggcccggg gcaatagcat cccggcctcc aggcccgggg 1400

 acgagggcgt ccctttccgc tttgacttca acgcattccg gagccgtctc 1450

 cgccacccgg tcctgggaac gagggccgat gagagtcagg agccccagag 1500

 ccaagtgcga gcccagcggg tagaaaatca aggagacaca gcggtcctgg 1550

 ggttgccttc cagatgaaga tctatcaaag atttgaagtc ttgtgtatgt 1600

 ggtcctagag gaccccaggc tgttataccg atccatgagg catctgaccc 1650

 cttccaaagg atgatgcagt ttgcttggca gagctataag cgttatgcaa 1700

 tggggaaaaa cgaactccgt ccactaacaa aagatggcta cgagggtaac 1750

 atgttcggag gcctcagcgg ggcaacagtc attgactccc tcgataccct 1800

 ctacctcatg gagctgaagg aggagttcca ggaggccaag gcctgggtgg 1850

 gagagagctt ccacctgaac gtgagcggag aagcatcctt gtttgaggtg 1900

 aacatccgct acatcggggg actcctctca gccttctacc tgacaggaga 1950

 agaggtgttc cgaataaagg ccatcaggct gggagagaag ctcctgccgg 2000

 cgttcaacac ccccacggga atcccaaagg gcgtggtgag cttcaaaagt 2050

 gggaactggg gctgggccac agccggcagc agcagcatct tggcggagtt 2100

 tggatccctg cacttggaat tcttacacct cactgaactc tctggcaacc 2150

 aggtcttcgc tgaaaaggtc aggaacatcc gcaaggtcct caggaagatc 2200

 gaaaagccct ttggcctcta ccccaacttc ctcagcccag tgagtgggaa 2250

 ctgggtgcaa caccatgtct cagttggagg actcggggac agtttttatg 2300

 aatatttgat caaatcctgg ttgatgtcgg gcaagacaga tatggaggct 2350

 aaaaatatgt actacgaagc cttggaggcg atagagacct acttgctgaa 2400

 tgtctctccc ggggggctga cctacattgc cgagtggcga ggggggattc 2450

 tggaccacaa gatggggcac ctggcctgtt tctccggggg catgatcgcc 2500

 cttggcgccg aggatgccaa ggaagaaaag agggcccact accgagagct 2550

 cgcagcccag atcaccaaga cgtgtcacga gtcatacgcc cgctcagaca 2600

 ccaaacttgg gcctgaggcc ttctggttta actccggcag agaggccgtg 2650

 gccacccagc tgagcgagag ctactacatc ctccggccag aggtggtgga 2700

 gagctacatg tacctgtggc gacagaccca caaccccatc tacagggagt 2750

 ggggctggga aggtggtgct ggccttggag aaatactgtc ggacagaagc 2800

 cggtttctct gggatccaag acgtgtacag tagcaccccc aaccacggac 2850

 aacaagcagc agagcttctt tctagcggag acactaaagt atctctatct 2900

 tctgttctct gaagatgact tgctctccct ggaagactgg gtgttcaaca 2950

 ccgaggccca cccactcccg gtgaaccact cagacagctc cggcagagcc 3000

 tggggcagac actgacccca tctcctgccg ccgccctggg gccgccgcag 3050

 ggatgccttg ccttttcagg atttgagact gttctcaaag ggattgggaa 3100

 cgaaggcccc atctcgggca gacccccagc agatgtgtcg gacaagcaac 3150

 ttcttttcct ctgtgaggag acaagacttg gagactcagc gatgtcaggc 3200

 cagggccatg gccacactgg cccacacatt cctttctaca gagaatttct 3250

 atgaagccca ctcacttgcc attccagggc caaaggaccg gaggtttgca 3300

 tatccgcccc ttgtatttga tttgcttcct tttggtttct tggtttttgt 3350

 ttttgcttga ttttgtcttt tctctacagt ttagttttgt cacaattaca 3400

 catatagttt tcaaaatcat gcactttcta aaatggtgtc atcctgaaaa 3450

 acaaaaccca gtgtttgcac acacacaaaa tcttgacccc gttatctata 3500

 ttttaaatgc tttttgccca acactgaccc tatgttcaac tttgtgtcat 3550

 ttaccttata atttgaggag gggtttccct ttgggcctca gtgttacaaa 3600

 ttactagtgc tattttcatt attattgtaa tggaaaaatc tgtggactag 3650

 aataaaagag tttattgaat tagaaaaaaa aaaaaaaaaa aaaaaaaaaa 3700

 aaaaaaaaaa aaaaaaaaaa aa 3722

<210> 5029
<211> 390
<212> PRT
<213> Homo sapien

<400> 5029
 Met Met Gln Phe Ala Trp Gln Ser Tyr Lys Arg Tyr Ala Met Gly
   1               5                  10                  15

 Lys Asn Glu Leu Arg Pro Leu Thr Lys Asp Gly Tyr Glu Gly Asn
                  20                  25                  30

 Met Phe Gly Gly Leu Ser Gly Ala Thr Val Ile Asp Ser Leu Asp
                  35                  40                  45

 Thr Leu Tyr Leu Met Glu Leu Lys Glu Glu Phe Gln Glu Ala Lys
                  50                  55                  60

 Ala Trp Val Gly Glu Ser Phe His Leu Asn Val Ser Gly Glu Ala
                  65                  70                  75

 Ser Leu Phe Glu Val Asn Ile Arg Tyr Ile Gly Gly Leu Leu Ser
                  80                  85                  90

 Ala Phe Tyr Leu Thr Gly Glu Glu Val Phe Arg Ile Lys Ala Ile
                  95                 100                 105

 Arg Leu Gly Glu Lys Leu Leu Pro Ala Phe Asn Thr Pro Thr Gly
                 110                 115                 120

 Ile Pro Lys Gly Val Val Ser Phe Lys Ser Gly Asn Trp Gly Trp
                 125                 130                 135

 Ala Thr Ala Gly Ser Ser Ser Ile Leu Ala Glu Phe Gly Ser Leu
                 140                 145                 150

 His Leu Glu Phe Leu His Leu Thr Glu Leu Ser Gly Asn Gln Val
                 155                 160                 165

 Phe Ala Glu Lys Val Arg Asn Ile Arg Lys Val Leu Arg Lys Ile
                 170                 175                 180

 Glu Lys Pro Phe Gly Leu Tyr Pro Asn Phe Leu Ser Pro Val Ser
                 185                 190                 195

 Gly Asn Trp Val Gln His His Val Ser Val Gly Gly Leu Gly Asp
                 200                 205                 210

 Ser Phe Tyr Glu Tyr Leu Ile Lys Ser Trp Leu Met Ser Gly Lys
                 215                 220                 225

 Thr Asp Met Glu Ala Lys Asn Met Tyr Tyr Glu Ala Leu Glu Ala
                 230                 235                 240

 Ile Glu Thr Tyr Leu Leu Asn Val Ser Pro Gly Gly Leu Thr Tyr
                 245                 250                 255

 Ile Ala Glu Trp Arg Gly Gly Ile Leu Asp His Lys Met Gly His
                 260                 265                 270

 Leu Ala Cys Phe Ser Gly Gly Met Ile Ala Leu Gly Ala Glu Asp
                 275                 280                 285

 Ala Lys Glu Glu Lys Arg Ala His Tyr Arg Glu Leu Ala Ala Gln
                 290                 295                 300

 Ile Thr Lys Thr Cys His Glu Ser Tyr Ala Arg Ser Asp Thr Lys
                 305                 310                 315

 Leu Gly Pro Glu Ala Phe Trp Phe Asn Ser Gly Arg Glu Ala Val
                 320                 325                 330

 Ala Thr Gln Leu Ser Glu Ser Tyr Tyr Ile Leu Arg Pro Glu Val
                 335                 340                 345

 Val Glu Ser Tyr Met Tyr Leu Trp Arg Gln Thr His Asn Pro Ile
                 350                 355                 360

 Tyr Arg Glu Trp Gly Trp Glu Gly Gly Ala Gly Leu Gly Glu Ile
                 365                 370                 375

 Leu Ser Asp Arg Ser Arg Phe Leu Trp Asp Pro Arg Arg Val Gln
                 380                 385                 390

<210> 5030
<211> 2025
<212> DNA
<213> Homo sapien

<400> 5030
 cttctgtgtg tgcacatgtg taatacatat ctgggatcaa agctatctat 50

 ataaagtcct tgattctgtg tgggttcaaa cacatttcaa agcttcagga 100

 tcctgaaagg ttttgctcta cttcctgaag acctgaacac cgctcccata 150

 aagccatggc ttgccttgga tttcagcggc acaaggctca gctgaacctg 200

 gctaccagga cctggccctg cactctcctg ttttttcttc tcttcatccc 250

 tgtcttctgc aaagcaatgc acgtggccca gcctgctgtg gtactggcca 300

 gcagccgagg catcgccagc tttgtgtgtg agtatgcatc tccaggcaaa 350

 gccactgagg tccgggtgac agtgcttcgg caggctgaca gccaggtgac 400

 tgaagtctgt gcggcaacct acatgatggg gaatgagttg accttcctag 450

 atgattccat ctgcacgggc acctccagtg gaaatcaagt gaacctcact 500

 atccaaggac tgagggccat ggacacggga ctctacatct gcaaggtgga 550

 gctcatgtac ccaccgccat actacctggg cataggcaac ggaacccaga 600

 tttatgtaat tgatccagaa ccgtgcccag attctgactt cctcctctgg 650

 atccttgcag cagttagttc ggggttgttt ttttatagct ttctcctcac 700

 agctgtttct ttgagcaaaa tgctaaagaa aagaagccct cttacaacag 750

 gggtctatgt gaaaatgccc ccaacagagc cagaatgtga aaagcaattt 800

 cagccttatt ttattcccat caattgagaa accattatga agaagagagt 850

 ccatatttca atttccaaga gctgaggcaa ttctaacttt tttgctatcc 900

 agctattttt atttgtttgt gcatttgggg ggaattcatc tctctttaat 950

 ataaagttgg atgcggaacc caaattacgt gtactacaat ttaaagcaaa 1000

 ggagtagaaa gacagagctg ggatgtttct gtcacatcag ctccactttc 1050

 agtgaaagca tcacttggga ttaatatggg gatgcagcat tatgatgtgg 1100

 gtcaaggaat taagttaggg aatggcacag cccaaagaag gaaaaggcag 1150

 ggagcgaggg agaagactat attgtacaca ccttatattt acgtatgaga 1200

 cgtttatagc cgaaatgatc ttttcaagtt aaattttatg ccttttattt 1250

 cttaaacaaa tgtatgatta catcaaggct tcaaaaatac tcacatggct 1300

 atgttttagc cagtgatgct aaaggttgta ttgcatatat acatatatat 1350

 atatatatat atatatatat atatatatat atatatatat tttaatttga 1400

 tagtattgtg catagagcca cgtatgtttt tgtgtatttg ttaatggttt 1450

 gaatataaac actatatggc agtgtctttc caccttgggt cccagggaag 1500

 ttttgtggag gagctcagga cactaataca ccaggtagaa cacaaggtca 1550

 tttgctaact agcttggaaa ctggatgagg tcatagcagt gcttgattgc 1600

 gtggaattgt gctgagttgg tgttgacatg tgctttgggg cttttacacc 1650

 agttcctttc aatggtttgc aaggaagcca cagctggtgg tatctgagtt 1700

 gacttgacag aacactgtct tgaagacaat ggcttactcc aggagaccca 1750

 caggtatgac cttctaggaa gctccagttc gatgggccca attcttacaa 1800

 acatgtggtt aatgccatgg acagaagaag gcagcaggtg gcagaatggg 1850

 gtgcatgaag gtttctgaaa attaacactg cttgtgtttt taactcaata 1900

 ttttccatga aaatgcaaca acatgtataa tatttttaat taaataaaaa 1950

 tctgtggtgg tcgttttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2000

 aaaaaaaaaa aaaaaaaaaa aaaaa 2025

<210> 5031
<211> 223
<212> PRT
<213> Homo sapien

<400> 5031
 Met Ala Cys Leu Gly Phe Gln Arg His Lys Ala Gln Leu Asn Leu
   1               5                  10                  15

 Ala Thr Arg Thr Trp Pro Cys Thr Leu Leu Phe Phe Leu Leu Phe
                  20                  25                  30

 Ile Pro Val Phe Cys Lys Ala Met His Val Ala Gln Pro Ala Val
                  35                  40                  45

 Val Leu Ala Ser Ser Arg Gly Ile Ala Ser Phe Val Cys Glu Tyr
                  50                  55                  60

 Ala Ser Pro Gly Lys Ala Thr Glu Val Arg Val Thr Val Leu Arg
                  65                  70                  75

 Gln Ala Asp Ser Gln Val Thr Glu Val Cys Ala Ala Thr Tyr Met
                  80                  85                  90

 Met Gly Asn Glu Leu Thr Phe Leu Asp Asp Ser Ile Cys Thr Gly
                  95                 100                 105

 Thr Ser Ser Gly Asn Gln Val Asn Leu Thr Ile Gln Gly Leu Arg
                 110                 115                 120

 Ala Met Asp Thr Gly Leu Tyr Ile Cys Lys Val Glu Leu Met Tyr
                 125                 130                 135

 Pro Pro Pro Tyr Tyr Leu Gly Ile Gly Asn Gly Thr Gln Ile Tyr
                 140                 145                 150

 Val Ile Asp Pro Glu Pro Cys Pro Asp Ser Asp Phe Leu Leu Trp
                 155                 160                 165

 Ile Leu Ala Ala Val Ser Ser Gly Leu Phe Phe Tyr Ser Phe Leu
                 170                 175                 180

 Leu Thr Ala Val Ser Leu Ser Lys Met Leu Lys Lys Arg Ser Pro
                 185                 190                 195

 Leu Thr Thr Gly Val Tyr Val Lys Met Pro Pro Thr Glu Pro Glu
                 200                 205                 210

 Cys Glu Lys Gln Phe Gln Pro Tyr Phe Ile Pro Ile Asn
                 215                 220

<210> 5032
<211> 564
<212> DNA
<213> Homo sapien

<400> 5032
 ggagtggaac catggtctgt agcctaggat actatatcac tattagctct 50

 ggacttcaac tagtctatag atttttttct ttattatgta ttttatgtac 100

 aggtaattgg ccttttaatt gctattatat atgagagcaa aatagaagac 150

 tgacattttc ttattagttc caaataacta gataagttaa tttgcagatg 200

 tataaaattt attgaaatca cctttgacat gtgttgtaac atttttaaaa 250

 aaatcattag ttattgtgct gctgcttctc agatattttt cagtgccacg 300

 aaagctttta ttatcagttc agtccctgcc cttaaggttc atctgacctc 350

 ccttcccctt ccacagattt gtattaagtg aatgattttt tctgtataag 400

 cattgggggg gattggggga ggtgggattt aaaggtgaat aaggggtagg 450

 cccttcacta aagaagcgta tctcctgtta ggaaactgac tatctaagca 500

 tagagttgtt gggttagctt tgaagttgaa gactgtgaat ctgtgtctca 550

 agtaaaaatc tagt 564

<210> 5033
<211> 43
<212> PRT
<213> Homo sapien

<400> 5033
 Ser Gly Thr Met Val Cys Ser Leu Gly Tyr Tyr Ile Thr Ile Ser
   1               5                  10                  15

 Ser Gly Leu Gln Leu Val Tyr Arg Phe Phe Ser Leu Leu Cys Ile
                  20                  25                  30

 Leu Cys Thr Gly Asn Trp Pro Phe Asn Cys Tyr Tyr Ile
                  35                  40

<210> 5034
<211> 1260
<212> DNA
<213> Homo sapien

<400> 5034
 aaaaattaac ttttcccttt tatacagaat ctgaaccaaa tttaccttac 50

 tttccttcca aaatatccac attcaggaat ataggtgaat aacaaataag 100

 gcagcatagc aaactgctca gactcaagcc aaattgaggt caacatagta 150

 tgccaaatcc atagtaaggc aaatccaccc ccctacccca atacttaaca 200

 cacagaatac tatgtgatat agaatgcact gaagacctac ggtcactggt 250

 agtttgagcc acaggccttc ctcatgtaac cagagacaga atgggctact 300

 tgcaaaaacg taactccttg tgtgtatatt aaatccataa aatctctggc 350

 agtaaagcca gcctgaaggg atggcctcac catcttagaa tactgagatc 400

 tcaccagaac actgtaagcc atataaacag tagggaaaga gtcagcaaca 450

 gtgaaaccat ctgtttaaaa tgggcaaaag cgattaaggg aaaaaaaaca 500

 ggtgaatttg aaaataaacc agggtaaggt aaattctaga aataatagca 550

 tttgaaatga aaacctcact taagttcact agaacagtaa acaggagatt 600

 gctgaatttt ttgaagacag caatgacctc acctagatga ctcaagtttg 650

 gggaacatca agattttgac gggtactata atgcttaata tgtccaaatt 700

 ttcaaaatga agtttctcag atattatttc tgccatagga gctacagtgt 750

 agagtatcac ataagtatct tgggctagag aaatgcagtt tatatatacc 800

 gttggatttt tataataaag tttcccaaga cctgttattt tgccagaaat 850

 gcttctagta tgcttctaga taaaattgcc ccttcagtga ctcatggtgt 900

 tcaaatgatc attttagtct gttgcttttt acaagggagt atttcaaatg 950

 tcttaagctt ttgataactt ataatttaag aacacacata aaacatttca 1000

 gtaggaaatc ctactaagta cactcaaaag agtgcctgct tatcagatag 1050

 cattcttttc aaacctctaa aataaaagac agtggagagc agaatcggta 1100

 atcatggtga ctcttgttac ccatgctgaa gtgcagtggc ccactaaaag 1150

 atccagctca aactcctgga ctgctcagct cccgagctgt cagattatga 1200

 cgcatgctgg ctgaagttaa actctaaaaa ccttaaatat agcacaccac 1250

 agatctagta 1260

<210> 5035
<211> 29
<212> PRT
<213> Homo sapien

<400> 5035
 Lys Leu Thr Phe Pro Phe Tyr Thr Glu Ser Glu Pro Asn Leu Pro
   1               5                  10                  15

 Tyr Phe Pro Ser Lys Ile Ser Thr Phe Arg Asn Ile Gly Glu
                  20                  25

<210> 5036
<211> 614
<212> DNA
<213> Homo sapien

<400> 5036
 ggtgagtccc tccccaggtg ggtctgcccc taccccgtgt gggcgggatt 50

 agctcccaga ggctggccag gccccacctg ggtgaggctt gaggtcaggg 100

 ccccaaggct cagattcagg cttggtggaa cagagcagga aagagacccg 150

 gtaccgaaag tgagcggggc aggcacctat gtcacatggg taatgggcag 200

 gggtcggtca ctggctttgg ctccagggcc agagcagtct gacttagtgt 250

 tgagctccaa gcatggaaca ctggagttgg ttcattttga ccagcaagcc 300

 tctaaatggg tgccttgatt actccaccgc aaggagaggg cagttgcctt 350

 tttatgacat gttaattcca gccaggtgag tcaccaggta gctctcatcc 400

 tcctgccagg ctcccctgcc tgtcggtttg gcattgtcag ataatgtgat 450

 cattcattga agtgacattt gagttccaaa ccagttttct cctttaacca 500

 tttcaccctc aggagtgatt ctcctttgtt tggcattgtc agggaatgtg 550

 atgatccatt caaatgactt ttgagttcca aatagtgttt ctactttaac 600

 ttcctaaatg aaaa 614

<210> 5037
<211> 105
<212> PRT
<213> Homo sapien

<400> 5037
 Gly Glu Ser Leu Pro Arg Trp Val Cys Pro Tyr Pro Val Trp Ala
   1               5                  10                  15

 Gly Leu Ala Pro Arg Gly Trp Pro Gly Pro Thr Trp Val Arg Leu
                  20                  25                  30

 Glu Val Arg Ala Pro Arg Leu Arg Phe Arg Leu Gly Gly Thr Glu
                  35                  40                  45

 Gln Glu Arg Asp Pro Val Pro Lys Val Ser Gly Ala Gly Thr Tyr
                  50                  55                  60

 Val Thr Trp Val Met Gly Arg Gly Arg Ser Leu Ala Leu Ala Pro
                  65                  70                  75

 Gly Pro Glu Gln Ser Asp Leu Val Leu Ser Ser Lys His Gly Thr
                  80                  85                  90

 Leu Glu Leu Val His Phe Asp Gln Gln Ala Ser Lys Trp Val Pro
                  95                 100                 105

<210> 5038
<211> 773
<212> DNA
<213> Homo sapien

<400> 5038
 gagactttta attatgcaat gccagactgc attgcataaa ccaaaggcca 50

 acagagaggt gacctttcaa attactggca caagaagagc tgagatcaga 100

 aagctccaac ttaatgcaaa catcgacaag aaatccgaca gaaatgactt 150

 ctgtgtctgg tcaacttaac ataacatgac atattgtcaa gcgcatttgg 200

 ctttttaggt agaattgtct ataaaggttt aactgcttta gaaaatataa 250

 atgtgaagat ttgtggtatt tgggtttata tataagatat ttctacattg 300

 aaaagagact ggaaaagctt ggtataagat ttgtaaaata tgtttgtaat 350

 aatgctaatg gaagaggtga gatttgggtg gggtggggtg tagatgggaa 400

 catggtttgg ggattgggga aagggaagtc atgctgttaa taaaatagtg 450

 aggcatgttg tataaagtgt gttttatgtc tcaattgaaa tgttatagag 500

 ataaatttaa aatagatcat gatgggtttt gaatctgatt tctaatttta 550

 aaatgttatg agcttttgtt gctttcctat ttcatacaca tttctttatg 600

 ggtttcactt agactgcatg aaattgcaga tgccaattac cttttaacaa 650

 aattaaattc acatatatgt ataatttgca tgtatatatt catggaattt 700

 tttattctac acgatatatt attttaaaat ggtttttcaa tgacaaaata 750

 aaaagtattt ttctatactt tca 773

<210> 5039
<211> 55
<212> PRT
<213> Homo sapien

<400> 5039
 Arg Leu Leu Ile Met Gln Cys Gln Thr Ala Leu His Lys Pro Lys
   1               5                  10                  15

 Ala Asn Arg Glu Val Thr Phe Gln Ile Thr Gly Thr Arg Arg Ala
                  20                  25                  30

 Glu Ile Arg Lys Leu Gln Leu Asn Ala Asn Ile Asp Lys Lys Ser
                  35                  40                  45

 Asp Arg Asn Asp Phe Cys Val Trp Ser Thr
                  50                  55

<210> 5040
<211> 590
<212> DNA
<213> Homo sapien

<400> 5040
 agtatttcgt tatagcagtc caagcaaact aatgcacata tcaaaactac 50

 tttagttttt ccactttgtt gcaaacaatt gcaagttgtc caggttttct 100

 gtcttccccc agcctgcaag tgctcagagg acacccaacc ctatgatctc 150

 agccaactca tgaagtttga tttcacaact tagtgatgtc ttcccagtgg 200

 aatcctaaat gataaggaaa atggtataga gccaagactt gaacattaac 250

 aacccaggag cacagaaaca gcacagttag ctgagaggcg ttatggagag 300

 aagcaaccga atgcacactg agcgctgtga gaagtccacg acagtgggga 350

 acagcgccca ccgtcacaaa aagaaagacc ctcggcaggt actttagagt 400

 cacgttcatg ctgtaatatg tggggaagaa agactattcc aaatggatct 450

 ggctttttaa aacaagggaa ttttccttgc tcttgggaac cagcaaaatc 500

 cagctgctca ttgaactgcc tgtctggaat ctcacaaatt tgcaccttga 550

 agttgttaat aaaggactaa gttgataatt cgaacaaaaa 590

<210> 5041
<211> 17
<212> PRT
<213> Homo sapien

<400> 5041
 Val Phe Arg Tyr Ser Ser Pro Ser Lys Leu Met His Ile Ser Lys
   1               5                  10                  15

 Leu Leu


<210> 5042
<211> 463
<212> DNA
<213> Homo sapien

<400> 5042
 caaggtttac atgaacaggg aacttgtctg ttttgtttat tactgtatcc 50

 cctatgctgg cacatactat gtaataagtg tttgttgagt gcatgagtga 100

 ataaccattc taaaaaactc tgatgtttaa agccctttgc tttatataag 150

 aattttactt ggaaccctgg tatttttgtt tgtatttgtt tgttaataaa 200

 tgtcaagagt tcagtagtaa gataggtttc agaaatgcta agttaaacag 250

 aataaagaaa gaatatgtat tacaggtcct ggcagagcct tgaatatgct 300

 aacatttgac agtgggagtc tttgagaatt atcacatgaa gctgctgtac 350

 attacaacac attctaggaa atgctgtctt agacaaaaac ctgtcatatt 400

 agaattgggg taaggggcac gatactgacc gtgaggcagc agattcctat 450

 ggactacatt aaa 463

<210> 5043
<211> 31
<212> PRT
<213> Homo sapien

<400> 5043
 Gln Gly Leu His Glu Gln Gly Thr Cys Leu Phe Cys Leu Leu Leu
   1               5                  10                  15

 Tyr Pro Leu Cys Trp His Ile Leu Cys Asn Lys Cys Leu Leu Ser
                  20                  25                  30

 Ala


<210> 5044
<211> 2321
<212> DNA
<213> Homo sapien

<400> 5044
 caaacatgca ttaagctcct gccaagcacc aggatgtgtc aggcacagca 50

 gggcagtggg gttgccacag agagggaatc aggactccag ccaggacact 100

 aggtagggaa gcaccagggg cctggggcgg agaaggcaac cagccagccc 150

 cgaggggcct ggaacatgca gctcagcttc cctgggattc tgcagaggga 200

 caggcaggtg gatgaaagct atgtccttca gctctagtcc catcccttcc 250

 gtcaagccaa gcccattcag caaggagtcc ttactccctg cctccacttt 300

 cttgccttcc atttcccctc tgcccatcga gtgttgctct tgtttctgcc 350

 tcaccccagt actgttctct gtacattcag gccttttttt tctggagata 400

 cttaatgatc actcttttcg tcattatgga tacagcagtg aaaaagaaaa 450

 atgaagcccc tgtggttttg gagttacttc ctagtcaagg gagacagata 500

 acctggtccc cgcccacagg gagctggcag cctgatgggg gccctaaggg 550

 tgcaactgta cttccccggg gacaaagaca gcgctacctt gggcagtggg 600

 tgggatgtct aattctgcct gtgggtctgg ggaaagaagg aagaagagac 650

 actggttagg taggactttt ctaggtggag ggaagatgga gaagagtact 700

 tagacaaaag gaaggatgtg tgtgcaggaa gctcccaaga acggtatgca 750

 tacggtgtat tgcggaacct cgtgtagctt catgtcactt tccttccctc 800

 tcccgttgtt gctgtcaccc tgttcgtaga aagtgagtgc tctttcctca 850

 aagattcccc tcagctcaca tggggacagg tatttttgga gcccctggct 900

 ggcatgaagc atgggtctgc aatggtagat ccatgtttgc cagcctgggg 950

 actcccacac cactatcctg agactgaccc ctgggccatg atttcctttc 1000

 agccaccgga accccttgat ccggaaatac gcggctgagc acctctcagc 1050

 tgtgctggag cagatcggcg ctgagaagct tctctcgggc accagagaca 1100

 gcacagacat gttggtgcac aacctggtga ggctggcaca ggactccaac 1150

 caggacacca gattttatgg ccggaagatg gtgaatatct tgatggcgaa 1200

 cactaagttt gatgcatttc tgaagcaatc tctcccatct tacgacttgc 1250

 agaaggtcat ggcggccatt aaacagcagg gaatagaaga taatgatgaa 1300

 cttccctctg ccaaaggccg caaggtgttg aggagtctgg tggtgtgtga 1350

 gaacgggctg cccatcaagg aggggctcag ctgcaatggc ccaaggctgg 1400

 tggggctgcg ctccacactg cagggccgcg gggagatggt ggagcagcta 1450

 cgggagctga cacggctgct ggaggccaag gacttccggt cccggatgga 1500

 aggcgtgggg cagctcctgg agctctgcaa ggccaagacg gagcttgtca 1550

 ctgcccacct ggtccaggct tcaggattcc aacaagaaag tgaaccagtg 1600

 ggcgctggag tccttcgcca agatgatccc cctcctcaga gagagcttac 1650

 accccatgct gctctccatc atcatcactg ttgcagacaa cctcaactcc 1700

 aagaactcag ggatttacgc tgctgccgtg gctgtgctgg atgcgatggt 1750

 tgagagcctg gacaaccttt gccttctacc agcgcttgct gggcgagtgc 1800

 gtttcctgag tggccgtgcg gtgctggatg tcacagatcg cctggcagtg 1850

 ctggtggcct cagtttaccc ccggaagcct caagctgtag agcggcatgt 1900

 ccttcccatc ctctggcact tcctgaacac cgccaccagg aatggcgccc 1950

 tgcctggacc cagcgggaac atccgcgggg tggtgtgccg gctgtccagg 2000

 agcctccagg agcacatggg ctcccgcctg ctggactttg ccgccagcca 2050

 gccaaagcac gtcctcaaga cgctccagga actcttagac tcagagtcct 2100

 tgggaggcag ccgcaaggcc actgacagag gggtggcccc tgacagcaag 2150

 acaactggca gctcataccc ttttcagctg gattaaagat ggatctgaaa 2200

 tgggcaatta ttatttatct tatttttttg atggactatt ctcctggtta 2250

 ctttccccct tagagttcca gatgtacatg gtatattttg aagtagaaat 2300

 aaaagaatta cttatttttc t 2321

<210> 5045
<211> 214
<212> PRT
<213> Homo sapien

<400> 5045
 Met Leu Val His Asn Leu Val Arg Leu Ala Gln Asp Ser Asn Gln
   1               5                  10                  15

 Asp Thr Arg Phe Tyr Gly Arg Lys Met Val Asn Ile Leu Met Ala
                  20                  25                  30

 Asn Thr Lys Phe Asp Ala Phe Leu Lys Gln Ser Leu Pro Ser Tyr
                  35                  40                  45

 Asp Leu Gln Lys Val Met Ala Ala Ile Lys Gln Gln Gly Ile Glu
                  50                  55                  60

 Asp Asn Asp Glu Leu Pro Ser Ala Lys Gly Arg Lys Val Leu Arg
                  65                  70                  75

 Ser Leu Val Val Cys Glu Asn Gly Leu Pro Ile Lys Glu Gly Leu
                  80                  85                  90

 Ser Cys Asn Gly Pro Arg Leu Val Gly Leu Arg Ser Thr Leu Gln
                  95                 100                 105

 Gly Arg Gly Glu Met Val Glu Gln Leu Arg Glu Leu Thr Arg Leu
                 110                 115                 120

 Leu Glu Ala Lys Asp Phe Arg Ser Arg Met Glu Gly Val Gly Gln
                 125                 130                 135

 Leu Leu Glu Leu Cys Lys Ala Lys Thr Glu Leu Val Thr Ala His
                 140                 145                 150

 Leu Val Gln Ala Ser Gly Phe Gln Gln Glu Ser Glu Pro Val Gly
                 155                 160                 165

 Ala Gly Val Leu Arg Gln Asp Asp Pro Pro Pro Gln Arg Glu Leu
                 170                 175                 180

 Thr Pro His Ala Ala Leu His His His His Cys Cys Arg Gln Pro
                 185                 190                 195

 Gln Leu Gln Glu Leu Arg Asp Leu Arg Cys Cys Arg Gly Cys Ala
                 200                 205                 210

 Gly Cys Asp Gly


<210> 5046
<211> 891
<212> DNA
<213> Homo sapien

<400> 5046
 gggacagagt gatcaaggca gagtgatcta aaggacacag tagtacttct 50

 ttaggaccct ggcagaatgg aagagagcat ctggcttcta aggcactgca 100

 caaacttgaa tgatcttctt cagaattgac aaggaaaggc catgttatgt 150

 tcaccctggg ttaagtttta agtgtatctt atttaatttt tttcaatatg 200

 agtcatctcc agatactgtg atgatttcca aataaccaga atctagatga 250

 ctagaaattt actctagctg gctttagaca ggaagcgtga ggacagaatc 300

 cagctgcttc cactccaggg taggtctgaa gccaaccgtc ctcggtttcc 350

 tggcctgtgg catcagtctg gttggattac acacaaagcc ctgcagatct 400

 gctgcttttc ctgattctcc tgtcctgagt gagtgcaagg ggctcccctg 450

 tcgccgatgt gttctttgaa gcagatgctg tgcctgatac ctgctggaga 500

 gtcccaccgc cttgagcttc tgggtcgaga aaggccaagt tgcacactac 550

 tgagagactg ccatgcaccc cctggaggcc tcagaacatt cgacatgctc 600

 cagtcatggc cacggcagtg actgctgatt gcctaacccc acatgtgttc 650

 tcccccttcc ctgataatca agcccctgat tttcagctgg gcacaaaata 700

 attcttccta gaacaactcc acgtgtgtta tcgcccttgc agctgggggt 750

 ggccaccact ggggagaggc agggtgaaga ggtcgaagga gcctgagtta 800

 gcagggatga gcagtggcca ggtaacccca gacccattat cctctggatt 850

 tcttttatgt gaaacaataa aatgtcttgt attcgaaaaa a 891

<210> 5047
<211> 1051
<212> DNA
<213> Homo sapien

<400> 5047
 gacccacttg tgtaatactt aattgcctgt gtttttacaa cacaagtcag 50

 aagttctggc gatagtggac tatcacccaa aaaagatttt ctgagacatc 100

 tcatcagagc tgctcgagta ccgcgcatga agacggtgtt agctctgcag 150

 ggcatgtgct aactaccaga cgatgaaaga acatttcctc tagtttctgg 200

 ataatgagca ggcacacagg taaagatgcc tttctcaggg ttgacgcctt 250

 ttgtttccta atgattctga tgattttgtt gaactagact tttaaatatt 300

 aattgttacc tgcatatgtt tgctgttgtg gtttgcagag ggctcagagg 350

 aacaagcatt ttaattggta tcctgggact gtaataactt tttattaaaa 400

 gtctggaaag atagtaatca aaaatagact ctcatctcta tcttctctgt 450

 gcccctggca aatatcctct tcattaattt tgtttttatt atttgccgtc 500

 aagatggtta tctctaaata tcagatgctt caatccacag tgataaccat 550

 gtgtgaatta atgcttgata agcttcaggt tatcaggtgg agaagtgtgg 600

 ttaaggcata cagaaagaaa aaatgcacag aaggaaaggg atagcaaggg 650

 gatactgtgc cttggtaagc gtggtgccac cgcagactaa aagcagatat 700

 aagtcaagtg ctactgactt aagtttggca aaatcactcc tcacagcccg 750

 ctctgtttta gaaatgttta tatttctgat atcacttttg ttaatttgaa 800

 gaacttttaa aataccatca ttgtttcaaa acaaaatgtg gaaggtgtgg 850

 atcaccttcc tgaatttaca gaaaagtttt tgggtacatt tctttgcgga 900

 agattggctg agatgtggtt cacggcaggg tggtgcccgt gccttgcgga 950

 tcacgttgtc tgtacactga ctgacatacc aacttagagt ctttgaaaat 1000

 gcccattggt aagtcaacat tgttttccct gaaagtcctg agacagaaaa 1050

 a 1051

<210> 5048
<211> 17
<212> PRT
<213> Homo sapien

<400> 5048
 Met Pro Ile Gly Lys Ser Thr Leu Phe Ser Leu Lys Val Leu Arg
   1               5                  10                  15

 Gln Lys


<210> 5049
<211> 744
<212> DNA
<213> Homo sapien

<400> 5049
 atcaggttca acgcagtgac tgctcagtag aagccatggc tcgcagacac 50

 tgcttctcct actggttact ggtatgctgg ttggtggtaa ctgtggcaga 100

 aggacaagaa gaggtattta cgcttcctgg agattcacaa aataatgcgg 150

 acgctaccga ctgccagatc tttacactca cccctccacc tgccccgagg 200

 agtccggtca caagggccca gcccatcaca aagacaccca ggtgtccctt 250

 ccattttttt ccacgaaggc ccagaatcca ttttaggttt ccaaacagac 300

 ctttcgtccc ttcaaggtgt aaccaccgtt ttccattcca gccattttat 350

 tggccacacc gttaccttac ttataggtat ttccccagaa gaagactcca 400

 gagaggaagc tcatctgagg aaagctgaga gggaagagaa acccaaacat 450

 actgaagcaa aaaaaagcct atccttcaga aaaaagcaac aaaaagattt 500

 ctgttttatc tttcgaaact aaaactattg gatttgaaga ttaagtatcc 550

 taaacatcac tgactagaaa ctgttctctt tgtcagcagt gaagatattg 600

 gatcataggt tattgatggt tgcaaaattg gacaataacc acgttatttt 650

 tatcctcaac ctcttatggt cacaggatat ttatgcaaat aaaatcttta 700

 aatgggaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 744

<210> 5050
<211> 130
<212> PRT
<213> Homo sapien

<400> 5050
 Met Ala Arg Arg His Cys Phe Ser Tyr Trp Leu Leu Val Cys Trp
   1               5                  10                  15

 Leu Val Val Thr Val Ala Glu Gly Gln Glu Glu Val Phe Thr Leu
                  20                  25                  30

 Pro Gly Asp Ser Gln Asn Asn Ala Asp Ala Thr Asp Cys Gln Ile
                  35                  40                  45

 Phe Thr Leu Thr Pro Pro Pro Ala Pro Arg Ser Pro Val Thr Arg
                  50                  55                  60

 Ala Gln Pro Ile Thr Lys Thr Pro Arg Cys Pro Phe His Phe Phe
                  65                  70                  75

 Pro Arg Arg Pro Arg Ile His Phe Arg Phe Pro Asn Arg Pro Phe
                  80                  85                  90

 Val Pro Ser Arg Cys Asn His Arg Phe Pro Phe Gln Pro Phe Tyr
                  95                 100                 105

 Trp Pro His Arg Tyr Leu Thr Tyr Arg Tyr Phe Pro Arg Arg Arg
                 110                 115                 120

 Leu Gln Arg Gly Ser Ser Ser Glu Glu Ser
                 125                 130

<210> 5051
<211> 2408
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 473-507, 768-1062, 2175-2286
<223> Unknown base

<400> 5051
 gttcttcctt tccttgtctc tcagcaaaat ataatcatct tagaaatttt 50

 cctctcttct attgtctatt ctatccacat atctagctta tttcctgtta 100

 ctgggatttg cctatgtttt tctatacctt acttctgtaa aattggtgag 150

 tttttctatt tatccctctt tctccttagt taatgaggta ccctaaagca 200

 ctagcactta ggaattagtc tacttgtcag caagagcgat ctattaacaa 250

 agggatatgt aagaaacagg agaactaaaa caatcttgtg gaaagggatt 300

 attttctaag cgtgtgtcta ctatattagt ttacttccga aaaacatcag 350

 ttacttctca taaatccatc ctgtgtttaa gaacataaaa tatagtgtgg 400

 ataacaaatg caaagcatgc aaattttcag gtaatcaggc gagccattac 450

 ttacggcaca ggtgtgccgc cannnnnnnn nnnnnnnnnn nnnnnnnnnn 500

 nnnnnnncta ctcaataaat agagagcata ggtgaaagaa ggacctaata 550

 cagaaatttt taacttttcc tgatactgtt tcaactttct tttgaatgtc 600

 tgatttaggc tgccctagtc atccttggac gttatccttg ggtgattcaa 650

 ttagtagcaa attgagttga ttttcaactt ctccattaat gtgcaggacc 700

 tgaaatcaaa gcaaaagtgt gctgttgagg gaaatgtttt gtcacctagg 750

 agataagtca agctgtgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 900

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 950

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1000

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1050

 nnnnnnnnnn nnacagtagc cctcattaat gggaataaag tatcatctga 1100

 gagtcatccc aaagcttact ccctcgttga gccgatgggc tgactgagac 1150

 tctggaaccc acgggtcact ggggtgtgtt agtgctcact gaggagacag 1200

 agctgttgca atactgagtt caagcagcac gactgactca cataatgtga 1250

 agtgaaacca gacagagctc cgaacttggt accttgggta gcaaaggcgg 1300

 cttccaatga tgattctata ccggtgaaca aagaaaaatt tgctttgaga 1350

 agctgagaaa atcgagctag acggcagtga agtaaaggct tctcttgcaa 1400

 aatctgagtg ccgatctgtg atgggaaaaa taacttccag ataaagcaaa 1450

 agttgatgtg gacaccagta cccagtaaat tactgtgaaa aaaaggcaac 1500

 ttctcttggt ccagtttacc tttagataaa tgttttaagg gtaaaaatat 1550

 gtgtatttca agatatgtct tatgtaaact tttttaagtt atgaaaatca 1600

 tccatattga aaaatagaat gttttctatt ttgaaactgt tttgcattgt 1650

 cagttactta agcagcctat tttacatttt ggtttttgag aacataatag 1700

 ggacctgtat actccttgtg gggccgctat tttaagactc ctgacagctc 1750

 atcctgcaaa attaaaatcc aaaatctaag tcgcaaaatt ctcttttctc 1800

 cttcctcagt tatttactta gagtgtagaa cagacatcct cttagagttt 1850

 tttgtaacta tcagttatca ttaacatcat atttttattc taaatccttc 1900

 catagaaaca ctgcttgtgg aaaaaaaaaa ggcttttact tggtttcacc 1950

 attgtacaga gggtaaatga aataactttc gctgaatatt gggtctataa 2000

 tactgttaca tttcctctat tattttaaca tctttgtgaa aaattcaaat 2050

 ttttactggt tcattcacat atcattttaa attggaggtt tagttcacat 2100

 acgatgaatg cacagctcgt aggtatacag tttaacgact tatgacagtg 2150

 gtataaccac aagaccagca acatnnnnnn nnnnnnnnnn nnnnnnnnnn 2200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 2250

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnacca actattattt 2300

 aacgtcatgt aaatgcaaat atgtagtata caatcttctg tggctggatt 2350

 ttttttcact caacattttt ttgggagatt ccttcatttg gttgcatgta 2400

 tcagtggt 2408

<210> 5052
<211> 111
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 12-110
<223> unknown amino acid

<220>
<221> Unsure
<222> 473-507, 768-1062, 2175-2286
<223> Unknown amino acid

<400> 5052
 Met Phe Cys His Leu Gly Asp Lys Ser Ser Cys Xaa Xaa Xaa Xaa
   1               5                  10                  15

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  95                 100                 105

 Xaa Xaa Xaa Xaa Xaa Gln
                 110

<210> 5053
<211> 333
<212> DNA
<213> Homo sapien

<400> 5053
 gagccacttt gcccagccca tttgtatatc tcctttggag aatatctagg 50

 ttcttttgaa ggtagctgta tataaactag ccaaattaac agactgtggt 100

 ttttagatgg ctttccatat ctacaagaac tatttagttc tcaaaactgg 150

 gaagaaatgt ttcagaggca tcattaattc ataatctaaa aatttatctt 200

 gggtttcctt ttttccccca gattctgtat cctccatagt cctattcatg 250

 acatgggtcg ttcatctctg tattctaaac cctcaatgaa ctgtagacag 300

 taataaatat ttattggatg aatggtctct cat 333

<210> 5054
<211> 24
<212> PRT
<213> Homo sapien

<400> 5054
 Glu Pro Leu Cys Pro Ala His Leu Tyr Ile Ser Phe Gly Glu Tyr
   1               5                  10                  15

 Leu Gly Ser Phe Glu Gly Ser Cys Ile
                  20

<210> 5055
<211> 5010
<212> DNA
<213> Homo sapien

<400> 5055
 ggcggctcgg gacggaggac gcgctagtgt gagtgcgggc ttctagaact 50

 acaccgaccc tcgtgtcctc ccttcatcct gcggggctgg ctggagcggc 100

 cgctccggtg ctgtccagca gccataggga gccgcacggg gagcgggaaa 150

 gcggtcgcgg ccccaggcgg ggcggccggg atggagcggg gccgcgagcc 200

 tgtggggaag gggctgtggc ggcgcctcga gcggctgcag gttcttctgt 250

 gtggcagttc agaatgatgg atcaagctag atcagcattc tctaacttgt 300

 ttggtggaga accattgtca tatacccggt tcagcctggc tcggcaagta 350

 gatggcgata acagtcatgt ggagatgaaa cttgctgtag atgaagaaga 400

 aaatgctgac aataacacaa aggccaatgt cacaaaacca aaaaggtgta 450

 gtggaagtat ctgctatggg actattgctg tgatcgtctt tttcttgatt 500

 ggatttatga ttggctactt gggctattgt aaaggggtag aaccaaaaac 550

 tgagtgtgag agactggcag gaaccgagtc tccagtgagg gaggagccag 600

 gagaggactt ccctgcagca cgtcgcttat attgggatga cctgaagaga 650

 aagttgtcgg agaaactgga cagcacagac ttcaccagca ccatcaagct 700

 gctgaatgaa aattcatatg tccctcgtga ggctggatct caaaaagatg 750

 aaaatcttgc gttgtatgtt gaaaatcaat ttcgtgaatt taaactcagc 800

 aaagtctggc gtgatcaaca ttttgttaag attcaggtca aagacagcgc 850

 tcaaaactcg gtgatcatag ttgataagaa cggtagactt gtttacctgg 900

 tggagaatcc tgggggttat gtggcgtata gtaaggctgc aacagttact 950

 ggtaaactgg tccatgctaa ttttggtact aaaaaagatt ttgaggattt 1000

 atacactcct gtgaatggat ctatagtgat tgtcagagca gggaaaatca 1050

 cctttgcaga aaaggttgca aatgctgaaa gcttaaatgc aattggtgtg 1100

 ttgatataca tggaccagac taaatttccc attgttaacg cagaactttc 1150

 attctttgga catgctcatc tggggacagg tgacccttac acacctggat 1200

 tcccttcctt caatcacact cagtttccac catctcggtc atcaggattg 1250

 cctaatatac ctgtccagac aatctccaga gctgctgcag aaaagctgtt 1300

 tgggaatatg gaaggagact gtccctctga ctggaaaaca gactctacat 1350

 gtaggatggt aacctcagaa agcaagaatg tgaagctcac tgtgagcaat 1400

 gtgctgaaag agataaaaat tcttaacatc tttggagtta ttaaaggctt 1450

 tgtagaacca gatcactatg ttgtagttgg ggcccagaga gatgcatggg 1500

 gccctggagc tgcaaaatcc ggtgtaggca cagctctcct attgaaactt 1550

 gcccagatgt tctcagatat ggtcttaaaa gatgggtttc agcccagcag 1600

 aagcattatc tttgccagtt ggagtgctgg agactttgga tcggttggtg 1650

 ccactgaatg gctagaggga tacctttcgt ccctgcattt aaaggctttc 1700

 acttatatta atctggataa agcggttctt ggtaccagca acttcaaggt 1750

 ttctgccagc ccactgttgt atacgcttat tgagaaaaca atgcaaaatg 1800

 tgaagcatcc ggttactggg caatttctat atcaggacag caactgggcc 1850

 agcaaagttg agaaactcac tttagacaat gctgctttcc ctttccttgc 1900

 atattctgga atcccagcag tttctttctg tttttgcgag gacacagatt 1950

 atccttattt gggtaccacc atggacacct ataaggaact gattgagagg 2000

 attcctgagt tgaacaaagt ggcacgagca gctgcagagg tcgctggtca 2050

 gttcgtgatt aaactaaccc atgatgttga attgaacctg gactatgaga 2100

 ggtacaacag ccaactgctt tcatttgtga gggatctgaa ccaatacaga 2150

 gcagacataa aggaaatggg cctgagttta cagtggctgt attctgctcg 2200

 tggagacttc ttccgtgcta cttccagact aacaacagat ttcgggaatg 2250

 ctgagaaaac agacagattt gtcatgaaga aactcaatga tcgtgtcatg 2300

 agagtggagt atcacttcct ctctccctac gtatctccaa aagagtctcc 2350

 tttccgacat gtcttctggg gctccggctc tcacacgctg ccagctttac 2400

 tggagaactt gaaactgcgt aaacaaaata acggtgcttt taatgaaacg 2450

 ctgttcagaa accagttggc tctagctact tggactattc agggagctgc 2500

 aaatgccctc tctggtgacg tttgggacat tgacaatgag ttttaaatgt 2550

 gatacccata gcttccatga gaacagcagg gtagtctggt ttctagactt 2600

 gtgctgatcg tgctaaattt tcagtagggc tacaaaacct gatgttaaaa 2650

 ttccatccca tcatcttggt actactagat gtctttaggc agcagctttt 2700

 aatacagggt agataacctg tacttcaagt taaagtgaat aaccacttaa 2750

 aaaatgtcca tgatggaata ttcccctatc tctagaattt taagtgcttt 2800

 gtaatgggaa ctgcctcttt cctgttgttg ttaatgaaaa tgtcagaaac 2850

 cagttatgtg aatgatctct ctgaatccta agggctggtc tctgctgaag 2900

 gttgtaagtg gttcgcttac tttgagtgat cctccaactt catttgatgc 2950

 taaataggag ataccaggtt gaaagacctc tccaaatgag atctaagcct 3000

 ttccataagg aatgtagcag gtttcctcat tcctgaaaga aacagttaac 3050

 tttcagaaga gatgggcttg ttttcttgcc aatgaggtct gaaatggagg 3100

 tccttctgct ggataaaatg aggttcaact gttgattgca ggaataaggc 3150

 cttaatatgt taacctcagt gtcatttatg aaaagagggg accagaagcc 3200

 aaagacttag tatattttct tttcctctgt cccttccccc ataagcctcc 3250

 atttagttct ttgttatttt tgtttcttcc aaagcacatt gaaagagaac 3300

 cagtttcagg tgtttagttg cagactcagt ttgtcagact ttaaagaata 3350

 atatgctgcc aaattttggc caaagtgtta atcttagggg agagctttct 3400

 gtccttttgg cactgagata tttattgttt atttatcagt gacagagttc 3450

 actataaatg gtgttttttt aatagaatat aattatcgga agcagtgcct 3500

 tccataatta tgacagttat actgtcggtt ttttttaaat aaaagcagca 3550

 tctgctaata aaacccaaca gatactggaa gttttgcatt tatggtcaac 3600

 acttaagggt tttagaaaac agccgtcagc caaatgtaat tgaataaagt 3650

 tgaagctaag atttagagat gaattaaatt taattagggg ttgctaagaa 3700

 gcgagcactg accagataag aatgctggtt ttcctaaatg cagtgaattg 3750

 tgaccaagtt ataaatcaat gtcacttaaa ggctgtggta gtactcctgc 3800

 aaaattttat agctcagttt atccaaggtg taactctaat tcccatttgc 3850

 aaaatttcca gtacctttgt cacaatccta acacattatc gggagcagtg 3900

 tcttccataa tgtataaaga acaaggtagt ttttacctac cacagtgtct 3950

 gtatcggaga cagtgatctc catatgttac actaagggtg taagtaatta 4000

 tcgggaacag tgtttcccat aattttcttc atgcaatgac atcttcaaag 4050

 cttgaagatc gttagtatct aacatgtatc ccaactccta taattcccta 4100

 tcttttagtt ttagttgcag aaacattttg tggtcattaa gcattgggtg 4150

 ggtaaattca accactgtaa aatgaaatta ctacaaaatt tgaaatttag 4200

 cttgggtttt tgttaccttt atggtttctc caggtcctct acttaatgag 4250

 atagcagcat acatttataa tgtttgctat tgacaagtca ttttaattta 4300

 tcacattatt tgcatgttac ctcctataaa cttagtgcgg acaagtttta 4350

 atccagaatt gaccttttga cttaaagcag agggactttg tatagaaggt 4400

 ttgggggctg tggggaagga gagtcccctg aaggtctgac acgtctgcct 4450

 acccattcgt ggtgatcaat taaatgtagg tatgaataag ttcgaagctc 4500

 cgtgagtgaa ccatcatata aacgtgtagt acagctgttt gtcatagggc 4550

 agttggaaac ggcctcctag ggaaaagttc atagggtctc ttcaggttct 4600

 tagtgtcact tacctagatt tacagcctca cttgaatgtg tcactactca 4650

 cagtctcttt aatcttcagt tttatcttta atctcctctt ttatcttgga 4700

 ctgacattta gcgtagctaa gtgaaaaggt catagctgag attcctggtt 4750

 cgggtgttac gcacacgtac ttaaatgaaa gcatgtggca tgttcatcgt 4800

 ataacacaat atgaatacag ggcatgcatt ttgcagcagt gagtctcttc 4850

 agaaaaccct tttctacagt tagggttgag ttacttccta tcaagccagt 4900

 acgtgctaac aggctcaata ttcctgaatg aaatatcaga ctagtgacaa 4950

 gctcctggtc ttgagatgtc ttctcgttaa ggagtagggc cttttggagg 5000

 taaaggtata 5010

<210> 5056
<211> 760
<212> PRT
<213> Homo sapien

<400> 5056
 Met Met Asp Gln Ala Arg Ser Ala Phe Ser Asn Leu Phe Gly Gly
   1               5                  10                  15

 Glu Pro Leu Ser Tyr Thr Arg Phe Ser Leu Ala Arg Gln Val Asp
                  20                  25                  30

 Gly Asp Asn Ser His Val Glu Met Lys Leu Ala Val Asp Glu Glu
                  35                  40                  45

 Glu Asn Ala Asp Asn Asn Thr Lys Ala Asn Val Thr Lys Pro Lys
                  50                  55                  60

 Arg Cys Ser Gly Ser Ile Cys Tyr Gly Thr Ile Ala Val Ile Val
                  65                  70                  75

 Phe Phe Leu Ile Gly Phe Met Ile Gly Tyr Leu Gly Tyr Cys Lys
                  80                  85                  90

 Gly Val Glu Pro Lys Thr Glu Cys Glu Arg Leu Ala Gly Thr Glu
                  95                 100                 105

 Ser Pro Val Arg Glu Glu Pro Gly Glu Asp Phe Pro Ala Ala Arg
                 110                 115                 120

 Arg Leu Tyr Trp Asp Asp Leu Lys Arg Lys Leu Ser Glu Lys Leu
                 125                 130                 135

 Asp Ser Thr Asp Phe Thr Ser Thr Ile Lys Leu Leu Asn Glu Asn
                 140                 145                 150

 Ser Tyr Val Pro Arg Glu Ala Gly Ser Gln Lys Asp Glu Asn Leu
                 155                 160                 165

 Ala Leu Tyr Val Glu Asn Gln Phe Arg Glu Phe Lys Leu Ser Lys
                 170                 175                 180

 Val Trp Arg Asp Gln His Phe Val Lys Ile Gln Val Lys Asp Ser
                 185                 190                 195

 Ala Gln Asn Ser Val Ile Ile Val Asp Lys Asn Gly Arg Leu Val
                 200                 205                 210

 Tyr Leu Val Glu Asn Pro Gly Gly Tyr Val Ala Tyr Ser Lys Ala
                 215                 220                 225

 Ala Thr Val Thr Gly Lys Leu Val His Ala Asn Phe Gly Thr Lys
                 230                 235                 240

 Lys Asp Phe Glu Asp Leu Tyr Thr Pro Val Asn Gly Ser Ile Val
                 245                 250                 255

 Ile Val Arg Ala Gly Lys Ile Thr Phe Ala Glu Lys Val Ala Asn
                 260                 265                 270

 Ala Glu Ser Leu Asn Ala Ile Gly Val Leu Ile Tyr Met Asp Gln
                 275                 280                 285

 Thr Lys Phe Pro Ile Val Asn Ala Glu Leu Ser Phe Phe Gly His
                 290                 295                 300

 Ala His Leu Gly Thr Gly Asp Pro Tyr Thr Pro Gly Phe Pro Ser
                 305                 310                 315

 Phe Asn His Thr Gln Phe Pro Pro Ser Arg Ser Ser Gly Leu Pro
                 320                 325                 330

 Asn Ile Pro Val Gln Thr Ile Ser Arg Ala Ala Ala Glu Lys Leu
                 335                 340                 345

 Phe Gly Asn Met Glu Gly Asp Cys Pro Ser Asp Trp Lys Thr Asp
                 350                 355                 360

 Ser Thr Cys Arg Met Val Thr Ser Glu Ser Lys Asn Val Lys Leu
                 365                 370                 375

 Thr Val Ser Asn Val Leu Lys Glu Ile Lys Ile Leu Asn Ile Phe
                 380                 385                 390

 Gly Val Ile Lys Gly Phe Val Glu Pro Asp His Tyr Val Val Val
                 395                 400                 405

 Gly Ala Gln Arg Asp Ala Trp Gly Pro Gly Ala Ala Lys Ser Gly
                 410                 415                 420

 Val Gly Thr Ala Leu Leu Leu Lys Leu Ala Gln Met Phe Ser Asp
                 425                 430                 435

 Met Val Leu Lys Asp Gly Phe Gln Pro Ser Arg Ser Ile Ile Phe
                 440                 445                 450

 Ala Ser Trp Ser Ala Gly Asp Phe Gly Ser Val Gly Ala Thr Glu
                 455                 460                 465

 Trp Leu Glu Gly Tyr Leu Ser Ser Leu His Leu Lys Ala Phe Thr
                 470                 475                 480

 Tyr Ile Asn Leu Asp Lys Ala Val Leu Gly Thr Ser Asn Phe Lys
                 485                 490                 495

 Val Ser Ala Ser Pro Leu Leu Tyr Thr Leu Ile Glu Lys Thr Met
                 500                 505                 510

 Gln Asn Val Lys His Pro Val Thr Gly Gln Phe Leu Tyr Gln Asp
                 515                 520                 525

 Ser Asn Trp Ala Ser Lys Val Glu Lys Leu Thr Leu Asp Asn Ala
                 530                 535                 540

 Ala Phe Pro Phe Leu Ala Tyr Ser Gly Ile Pro Ala Val Ser Phe
                 545                 550                 555

 Cys Phe Cys Glu Asp Thr Asp Tyr Pro Tyr Leu Gly Thr Thr Met
                 560                 565                 570

 Asp Thr Tyr Lys Glu Leu Ile Glu Arg Ile Pro Glu Leu Asn Lys
                 575                 580                 585

 Val Ala Arg Ala Ala Ala Glu Val Ala Gly Gln Phe Val Ile Lys
                 590                 595                 600

 Leu Thr His Asp Val Glu Leu Asn Leu Asp Tyr Glu Arg Tyr Asn
                 605                 610                 615

 Ser Gln Leu Leu Ser Phe Val Arg Asp Leu Asn Gln Tyr Arg Ala
                 620                 625                 630

 Asp Ile Lys Glu Met Gly Leu Ser Leu Gln Trp Leu Tyr Ser Ala
                 635                 640                 645

 Arg Gly Asp Phe Phe Arg Ala Thr Ser Arg Leu Thr Thr Asp Phe
                 650                 655                 660

 Gly Asn Ala Glu Lys Thr Asp Arg Phe Val Met Lys Lys Leu Asn
                 665                 670                 675

 Asp Arg Val Met Arg Val Glu Tyr His Phe Leu Ser Pro Tyr Val
                 680                 685                 690

 Ser Pro Lys Glu Ser Pro Phe Arg His Val Phe Trp Gly Ser Gly
                 695                 700                 705

 Ser His Thr Leu Pro Ala Leu Leu Glu Asn Leu Lys Leu Arg Lys
                 710                 715                 720

 Gln Asn Asn Gly Ala Phe Asn Glu Thr Leu Phe Arg Asn Gln Leu
                 725                 730                 735

 Ala Leu Ala Thr Trp Thr Ile Gln Gly Ala Ala Asn Ala Leu Ser
                 740                 745                 750

 Gly Asp Val Trp Asp Ile Asp Asn Glu Phe
                 755                 760

<210> 5057
<211> 2629
<212> DNA
<213> Homo sapien

<400> 5057
 caggcctgga ggagaaatga catctctcag ccctctcagc tgcaccggac 50

 caccaacagt tgtgattcaa tgggcatgaa ttgctgtgtg atgctgggga 100

 ggtgtttgtg attcttgaca aagtcatttg aatccatcac ttcaagagag 150

 tgaaaggagc cccgtctgat ctgttggtgt tgtaggaaga aacatgagtc 200

 agcaaaacac cagtggggac tgcctgtttg acggtgtcaa cgagctgatg 250

 aaaaccctac agtttgcagt ccacatcccc accttcgtcc tgggcctgct 300

 cctcaacctg ctggccatcc atggcttcag caccttcctt aagaacaggt 350

 ggcccgatta tgctgccacc tccatctaca tgatcaacct ggcagtcttt 400

 gacctgctgc tggtgctctc cctcccattc aagatggtcc tgtcccaggt 450

 acagtccccc ttcccgtccc tgtgcaccct ggtggagtgc ctttacttcg 500

 tcagcatgta cggaagcgtc ttcaccatct gcttcatcag catggaccgg 550

 ttcttggcca tccgttaccc gctactggtg agccacctcc ggtcccccag 600

 gaagatcttt gggatctgct gcaccatctg ggtcctggtg tggaccggaa 650

 gcatccctat ctacagtttc catgggaaag tggaaaaata catgtgcttc 700

 cacaacatgt ctgatgatac ctggagcgcc aaggtcttct tcccgctgga 750

 ggtgtttggc ttcctccttc ccatgggcat catgggcttc tgctgctcca 800

 ggagcatcca catcctgctg ggccgccgag accacaccca ggactgggtg 850

 cagcagaaag cctgcatcta cagcatcgca gccagcctgg ctgtcttcgt 900

 ggtctccttc ctcccagtcc acctggggtt cttcctgcag ttcctggtga 950

 gaaacagctt tatcgtagag tgcagagcca agcagagcat cagcttcttc 1000

 ttgcaattgt ccatgtgttt ctccaacgtc aactgctgcc tggatgtttt 1050

 ctgctactac tttgtcatca aagaattccg catgaacatc agggcccacc 1100

 ggccttccag ggtccagctg gtcctgcagg acaccacgat ctcccggggc 1150

 taacggaagg acatcctgtt caggggaaga aagccctggc cctgaattct 1200

 ggtaacggat atcgcgttcc agggttttga tgtggtggga tgatccgcac 1250

 catcttcact gatgtgcttc cctttgatgc ccattgagtg ccagctttgc 1300

 tcattatacc ccaaagacct tttttccact gcccagacag cttataccac 1350

 ccagtgttca gggatctctg aagaacccac agaccaggtg aattactgat 1400

 ttctaagtcc aaaaactata gagcagaaga attgagaaag agaatgagac 1450

 catgtcaaca aggctgtttc caactctccc cattttcctg ttcgactggg 1500

 aggttctgga aagaaagaga gagagagaaa agaggtggat ggagggaagg 1550

 gtgaggaaga gagcgtcaat gaaggggtgg aagtggatgt ggaggagtga 1600

 ccagaccaga ccagaccaga ccagagggat cggaggctca ggccccctga 1650

 gctgggcctc taagaaccac agccacagag tcaggctctg cagacccaga 1700

 ggtaaggctg cctggctgcc ccaaacccca gacactcctc tccttgcctg 1750

 caggctgccc tctcccatgg ccaccctaga cagagacacc acccgtgata 1800

 ctctgaggga gccagacttt cacatgcaac ggggcatttg gggctggttc 1850

 gggtcagtgt ctacgggtgg tggatttagt gaccaccctc ctcccacttc 1900

 tttctctgca cgaggagttg ggagcctgcc tggtggagtt gagtgatgcc 1950

 cgtcatgtgc acttgggtct accaatgtgc ttaaggccag atgggcttcc 2000

 taagagacaa gggtgggtgg acctaaccaa ctatcatccc cagcgatgtt 2050

 caaacataaa atcttatcta tgtgcagcat gactctctcc aggtgacaga 2100

 aagggctcta gacagctgag aggacctgat catgtaggga gggacgggga 2150

 ggggagccag gacccaggag ctgcatggct gtaagaggaa ggtccttgga 2200

 gggtatcagc agtctcagtg tgatgtgaca actatggacc tgtgggtgtg 2250

 ccctggggac ccctgaccca tcccaaaaca ctgtggaaag aagggcctct 2300

 tctccgtggg gacccgtgtc tgtgggagcg ggcacaggtc catgctgcag 2350

 gccactacgg ctgctcggca ggagggccga gagtttggac ccacatagct 2400

 gcaacccaag ctggcccata atcagcagtg gggcccagca gcacaggagg 2450

 ggcggacggt tagctttgga aaaaatgact tgattaatct gattcgccaa 2500

 ataaatagat tcatgtgatg ccttgtgaaa aaaaaaaaaa aaaaaaaaaa 2550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2600

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2629

<210> 5058
<211> 319
<212> PRT
<213> Homo sapien

<400> 5058
 Met Ser Gln Gln Asn Thr Ser Gly Asp Cys Leu Phe Asp Gly Val
   1               5                  10                  15

 Asn Glu Leu Met Lys Thr Leu Gln Phe Ala Val His Ile Pro Thr
                  20                  25                  30

 Phe Val Leu Gly Leu Leu Leu Asn Leu Leu Ala Ile His Gly Phe
                  35                  40                  45

 Ser Thr Phe Leu Lys Asn Arg Trp Pro Asp Tyr Ala Ala Thr Ser
                  50                  55                  60

 Ile Tyr Met Ile Asn Leu Ala Val Phe Asp Leu Leu Leu Val Leu
                  65                  70                  75

 Ser Leu Pro Phe Lys Met Val Leu Ser Gln Val Gln Ser Pro Phe
                  80                  85                  90

 Pro Ser Leu Cys Thr Leu Val Glu Cys Leu Tyr Phe Val Ser Met
                  95                 100                 105

 Tyr Gly Ser Val Phe Thr Ile Cys Phe Ile Ser Met Asp Arg Phe
                 110                 115                 120

 Leu Ala Ile Arg Tyr Pro Leu Leu Val Ser His Leu Arg Ser Pro
                 125                 130                 135

 Arg Lys Ile Phe Gly Ile Cys Cys Thr Ile Trp Val Leu Val Trp
                 140                 145                 150

 Thr Gly Ser Ile Pro Ile Tyr Ser Phe His Gly Lys Val Glu Lys
                 155                 160                 165

 Tyr Met Cys Phe His Asn Met Ser Asp Asp Thr Trp Ser Ala Lys
                 170                 175                 180

 Val Phe Phe Pro Leu Glu Val Phe Gly Phe Leu Leu Pro Met Gly
                 185                 190                 195

 Ile Met Gly Phe Cys Cys Ser Arg Ser Ile His Ile Leu Leu Gly
                 200                 205                 210

 Arg Arg Asp His Thr Gln Asp Trp Val Gln Gln Lys Ala Cys Ile
                 215                 220                 225

 Tyr Ser Ile Ala Ala Ser Leu Ala Val Phe Val Val Ser Phe Leu
                 230                 235                 240

 Pro Val His Leu Gly Phe Phe Leu Gln Phe Leu Val Arg Asn Ser
                 245                 250                 255

 Phe Ile Val Glu Cys Arg Ala Lys Gln Ser Ile Ser Phe Phe Leu
                 260                 265                 270

 Gln Leu Ser Met Cys Phe Ser Asn Val Asn Cys Cys Leu Asp Val
                 275                 280                 285

 Phe Cys Tyr Tyr Phe Val Ile Lys Glu Phe Arg Met Asn Ile Arg
                 290                 295                 300

 Ala His Arg Pro Ser Arg Val Gln Leu Val Leu Gln Asp Thr Thr
                 305                 310                 315

 Ile Ser Arg Gly


<210> 5059
<211> 975
<212> DNA
<213> Homo sapien

<400> 5059
 gctaagttgc catgacatgt agatttaaaa gataaacata aaaataactt 50

 atatttatta tcagtcatgg attccaagat tatttatgag aacttccaat 100

 atacctggcc caggaagaat atggctccta acttagggga tctcaccagc 150

 caatgggaaa gactaagcag atgtgtttac tggcaataca ttctgatgag 200

 ggacacctaa tggtgagtag agggtgcgac ggctcctaga aagagtcaaa 250

 gattagagaa gttcatcagg aaaaaacgat aaagtttcca tcaggagaat 300

 acaccctagt aaaggctcaa agtctaaaga gtttaaggac ttctagggac 350

 tgaaaaaatt ctgtataaca ggagggaagg tgggtgtgga agaatagcca 400

 agaaggaaaa atagccaaga agtcagtgga aggaacattg catcataggc 450

 cttgctgaga aattggaatg aatgacagta tttgaataac gctttgctca 500

 gttctgtagt ttcgattcga aatgcagact taaaaagtcg atgaacattc 550

 agacatttct ctttaaacaa gacttcccct tctattcttt agagttggaa 600

 attattctct gcttgggaat agttttcaat atgttccaga cattataaat 650

 gacttccctt ctatttccat gtatttccca tgttgattac agccaggctg 700

 atcagagtaa agcaccaggt gtcatagcat cctaatatta tatgaatcat 750

 gcatttatcc attcatctat gcatgtatcc agggaaaaca gatttttccc 800

 cctactttat cggttctaca gattcagatt cctgtatatt taggtaacat 850

 tccaagggga tagatgtgct cttataaaag actgcttact tcagcaagac 900

 agtttctaaa ccctttactt ttgagaacaa ttctccaggt attctcgggg 950

 gcggtggggg cagaagggaa gcaaa 975

<210> 5060
<211> 37
<212> PRT
<213> Homo sapien

<400> 5060
 Met Cys Ser Tyr Lys Arg Leu Leu Thr Ser Ala Arg Gln Phe Leu
   1               5                  10                  15

 Asn Pro Leu Leu Leu Arg Thr Ile Leu Gln Val Phe Ser Gly Ala
                  20                  25                  30

 Val Gly Ala Glu Gly Lys Gln
                  35

<210> 5061
<211> 703
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 99-116
<223> Unknown base

<400> 5061
 agagaataag tggttgaaag tcaacatgcc tagacaaccc agcaaactag 50

 aagacaccat aagaatgcgt aattattatt ctttatatgt ttataacann 100

 nnnnnnnnnn nnnnnntaac agctcaagac gcaggtagta tagtaatttt 150

 tgccccatac tgctgaatgt tttgcctggc aaatactggg aatggggcaa 200

 ttcctgtggc agttttgttt tccaataatt gttttttctt atatcgggga 250

 tgacaaatgc ttgtcacaaa gagtagcctt gttgattaca cttataaatc 300

 ttcgggagac ttcttcaatg agtcagtgtt agagctttca gtttccataa 350

 atgcagattt cctttactca gttttctttt aaacatgagc tgatctttct 400

 tagtttgcac tataataccc tccactgaag tctcactgca actgctttta 450

 agtatatgtg aagagaaact agccctttgc taaaatagtt gcatgtttca 500

 cgggccagtg agtcatttag tcatacactt aagaactttc cacctttcaa 550

 gtgtttatca tcacctcgga tttcacggcc taatgccagt caatttcatg 600

 gggcatagaa gccctgtacg tattagtttg ggccattatt gtatcagtct 650

 tgtttattcc cagaaaagtc ttatcaagaa aagagggagt gactataatc 700

 aga 703

<210> 5062
<211> 69
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 99-116
<223> Unknown amino acid

<400> 5062
 Met Phe His Gly Pro Val Ser His Leu Val Ile His Leu Arg Thr
   1               5                  10                  15

 Phe His Leu Ser Ser Val Tyr His His Leu Gly Phe His Gly Leu
                  20                  25                  30

 Met Pro Val Asn Phe Met Gly His Arg Ser Pro Val Arg Ile Ser
                  35                  40                  45

 Leu Gly His Tyr Cys Ile Ser Leu Val Tyr Ser Gln Lys Ser Leu
                  50                  55                  60

 Ile Lys Lys Arg Gly Ser Asp Tyr Asn
                  65

<210> 5063
<211> 4312
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3536-3560
<223> Unknown base

<400> 5063
 gtgacacgta agttgggcag gaggtggcgg ggcggcagag gcaccagccg 50

 acccgtcagt gacaccgctg tgccgtcccc aaaaccagcc gagacagctg 100

 gcccccaccc ttccacccat tgggcaggcc gcacgggggc gcggcccgga 150

 gtcctggtcc ctttgttggg cgcgcacccc ctcccttagg tggcaacaaa 200

 gtcgtgcagt gggagccgcc gcgatagggc ggggagtggc cagggcggga 250

 ctccaagaac tgcccggggg cagcggggcc aaaaagtggg aagaaggaaa 300

 aaaggcagga ggcatctggg gacaggcgcg agggcagccg gctctgaagt 350

 atgcggaggg cctcctcccg gccccgggca ttcgcggaga acgagcctcg 400

 cagaagtttg gctgcagctg cccgggcggc gtcgatggct gcgcgccccg 450

 cgccgcgcgg gggctgagcg ggcgccactt cccctccggg ccggcttttg 500

 tgtctggcat ctcctcctca tgctgcgtct ggccacctac tgcggcggcc 550

 gctgctgaga cgctcgctcg gaccaagggg aggagacggc gggggcggcc 600

 gcggctttgg gtccaggcgg gactatggga aacgggatgt gctcccgaaa 650

 gcagaagcgg attttccaga cgctgctgct gctgaccgtc gtgttcggct 700

 ttctctacgg cgcgatgctc tactacgagc tgcagacgca gctgcggaaa 750

 gccgaggcgg tggcgctcaa gtaccagcag caccaggagt ccctctccgc 800

 ccagttacaa gttgtatatg aacacagatc aagattagag aaatccttgc 850

 aaaaagaaag acttgaacat aaaaaagcaa aggaagattt tcttgtttat 900

 aagttagaag cacaagaaac attaaataaa ggaaggcaag attccaatag 950

 cagatacagt gcactgaatg tccaacatca gatgttgaaa agccaacacg 1000

 aggagctaaa gaaacagcac agtgacttgg aagaggaaca tcgcaaacaa 1050

 ggggaagact tcagtagaac atttaatgac cataagcaaa aatacttgca 1100

 gctccagcaa gaaaaagaac aagaactttc taagctaaaa gagactgtat 1150

 acaatttgag agaagagaat agacaactaa ggaaagcaca ccaagacata 1200

 catacacagc ttcaagatgt caagcaacag cataagaatt tactctccga 1250

 gcatgaacaa cttgtagtga ctttggaaga ccacaagagt gcactagctg 1300

 ctgcacagac tcaagttgca gaatataaac aactgaaaga tactctgaat 1350

 aggattccaa gccttcgaaa acctgatcca gcagaacagc aaaatgtgac 1400

 ccaggtggca cattctccac aaggttacaa cacagcaagg gagaagccaa 1450

 cccgagaggt gcaggaggtg tctcgaaata atgatgtgtg gcagaaccat 1500

 gaagcagttc ctggaagagc agaagacaca aaactctatg ctcccaccca 1550

 taaggaggca gaatttcagg ctcccccaga gccaatccaa caagaagtgg 1600

 aacgcagaga acctgaggag catcaggtgg aagaggagca cagaaaggcc 1650

 ctggaggagg aagaaatgga gcaggtcggg caagcagaac atcttgagga 1700

 ggaacacgat ccatcaccag aggagcagga tcgggagtgg aaagagcagc 1750

 atgagcaacg agaagcagcc aacctcctgg aagggcacgc gcgtgctgag 1800

 gtgtaccctt cagccaagcc aatgatcaaa ttccaatcac cctatgagga 1850

 acagttggaa cagcagagac tggcagtgca gcaggtggag gaggcccagc 1900

 agctgcggga acaccaggaa gctttgcacc agcagaggct gcaggggcac 1950

 ttactacggc agcaggaaca gcagcagcag caggtggcaa gagagatggc 2000

 cctgcagagg caggctgagc ttgaggaggg ccggccgcag caccaggagc 2050

 agctccggca gcaagctcat tatgatgcta tggataatga tatcgttcag 2100

 ggagcagagg accagggaat ccaaggagag gaaggagcct atgaaagaga 2150

 caaccagcac caagatgaag cagaaggaga tccaggtaat agacatgagc 2200

 ctcgtgaaca aggaccccga gaagccgacc cagaatctga ggcagatagg 2250

 gcagctgtag aagatataaa cccagcagat gaccctaata atcaaggtga 2300

 ggatgaattt gaagaagccg agcaagtgag agaagaaaat ttgccagatg 2350

 aaaatgaaga gcaaaaacaa agtaatcaaa agcaagagaa tacagaagtg 2400

 gaggaacatt tggtgatggc aggaaatcca gaccagcagg aggacaatgt 2450

 tgatgaacag taccaggaag aggcagaaga ggaggttcag gaagatttga 2500

 ctgaagagaa aaaaagggaa ctggagcata atgctgaaga gacctatggt 2550

 gaaaatgatg aaaatactga tgataaaaat aatgatggag aagagcaaga 2600

 agttcgagat gacaaccgcc ccaaaggccg agaggaacac tacgaggagg 2650

 aagaagagga ggaagaagac ggggctgcag ttgctgagaa atcacatcga 2700

 agagctgaaa tgtagcggca cccaatttct agacaacgct cagccaacgg 2750

 attcttttca agctgctcaa acataaatct gcctactgaa ctctaggata 2800

 tttaattaca aaaattaaga acttagactt ttttaaaact tttgtattag 2850

 aaatgcgcat acatttatat gaatatattt tgataacgta ggtctagagc 2900

 ttcttttata ttcaagctaa acatgaaaaa gaagaaaaac aataaagtaa 2950

 acctgagccc ccacgtccca atttttttaa tagattatgt gatgttggaa 3000

 agctcattga ttttgtatat gtttcagcgt gttacctttc tggcttccag 3050

 ttcccaggtg ttctttgttt gcctttgata aaatacagga tttaagaaca 3100

 gagagtactg caaaatgcca tgcagacttt aaagagaatg gcctgtttac 3150

 taattgctgc ccttctgatg tctttatgta tagctctgat agaattttca 3200

 ccagtctatg tatctctgga gtgagatcta tgtacaaagt gacatacaat 3250

 tggaaatcca tttttgttgt aaagacattg tttttcagac ttttcagatc 3300

 aattagaaaa atgtcattgc tttaaaatca tagctgttct gtttaagagg 3350

 aattgaattt aaaaatgaga gagtattaaa actcatgtgg cagtatcctg 3400

 gtcttaatca ggtattgcag tgttcaaaca aggtatggac acatcaacat 3450

 attcaccttt tggaaggact agtgacttgg ttaaaaacta atgagtgttt 3500

 gcgtgtggtg tttctatgcg agcacccatt ctcaannnnn nnnnnnnnnn 3550

 nnnnnnnnnn gaagccattg attgatattc ttgtttcagt gtctggttcc 3600

 ctataagtaa tatatatttc ctctttaagc tctgtgcctc aatatgcaat 3650

 cactttgata ataagtataa atatgaagac ataccaaact gcaaatagga 3700

 ttatttttca aaactatatg gtgaaacata tggtgatatg atagacttat 3750

 ggtttttctg tttgctggga ttgggtctgc tttttgccta tgtgtaaggc 3800

 attttaatca ttgtgaatat aatagattcc ttaaaataag aaaattaaaa 3850

 atcagaaact tcccttggag tagagacatt tcagttgcaa gcataaagat 3900

 ttttaaatat ataacactag gttatataat tcatatatgt gtggttttgt 3950

 attaataatc aaattaataa aaacatttca ttttctacca ttgtatgaac 4000

 gtaattttat tttttaataa ccacactcat agatggtttt gattgttcca 4050

 gttgagtgat tgtgtatgta cgcataggaa tgttttgttc agttgtactt 4100

 tgtatttcca ataatcagaa atcttacctt tatgtataaa aacccattat 4150

 gtaatgtaaa atgtataata ttgtacataa tattcagaat acaattattt 4200

 tggtaaatta gcttgtattt ttaatgtccc agttgcagta tttaattatt 4250

 tgaaccatac tgaaagttgg taatagtcaa taaagctaaa aaaaaaaagt 4300

 ggcaaatctt tt 4312

<210> 5064
<211> 696
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3536-3560
<223> Unknown amino acid

<400> 5064
 Met Gly Asn Gly Met Cys Ser Arg Lys Gln Lys Arg Ile Phe Gln
   1               5                  10                  15

 Thr Leu Leu Leu Leu Thr Val Val Phe Gly Phe Leu Tyr Gly Ala
                  20                  25                  30

 Met Leu Tyr Tyr Glu Leu Gln Thr Gln Leu Arg Lys Ala Glu Ala
                  35                  40                  45

 Val Ala Leu Lys Tyr Gln Gln His Gln Glu Ser Leu Ser Ala Gln
                  50                  55                  60

 Leu Gln Val Val Tyr Glu His Arg Ser Arg Leu Glu Lys Ser Leu
                  65                  70                  75

 Gln Lys Glu Arg Leu Glu His Lys Lys Ala Lys Glu Asp Phe Leu
                  80                  85                  90

 Val Tyr Lys Leu Glu Ala Gln Glu Thr Leu Asn Lys Gly Arg Gln
                  95                 100                 105

 Asp Ser Asn Ser Arg Tyr Ser Ala Leu Asn Val Gln His Gln Met
                 110                 115                 120

 Leu Lys Ser Gln His Glu Glu Leu Lys Lys Gln His Ser Asp Leu
                 125                 130                 135

 Glu Glu Glu His Arg Lys Gln Gly Glu Asp Phe Ser Arg Thr Phe
                 140                 145                 150

 Asn Asp His Lys Gln Lys Tyr Leu Gln Leu Gln Gln Glu Lys Glu
                 155                 160                 165

 Gln Glu Leu Ser Lys Leu Lys Glu Thr Val Tyr Asn Leu Arg Glu
                 170                 175                 180

 Glu Asn Arg Gln Leu Arg Lys Ala His Gln Asp Ile His Thr Gln
                 185                 190                 195

 Leu Gln Asp Val Lys Gln Gln His Lys Asn Leu Leu Ser Glu His
                 200                 205                 210

 Glu Gln Leu Val Val Thr Leu Glu Asp His Lys Ser Ala Leu Ala
                 215                 220                 225

 Ala Ala Gln Thr Gln Val Ala Glu Tyr Lys Gln Leu Lys Asp Thr
                 230                 235                 240

 Leu Asn Arg Ile Pro Ser Leu Arg Lys Pro Asp Pro Ala Glu Gln
                 245                 250                 255

 Gln Asn Val Thr Gln Val Ala His Ser Pro Gln Gly Tyr Asn Thr
                 260                 265                 270

 Ala Arg Glu Lys Pro Thr Arg Glu Val Gln Glu Val Ser Arg Asn
                 275                 280                 285

 Asn Asp Val Trp Gln Asn His Glu Ala Val Pro Gly Arg Ala Glu
                 290                 295                 300

 Asp Thr Lys Leu Tyr Ala Pro Thr His Lys Glu Ala Glu Phe Gln
                 305                 310                 315

 Ala Pro Pro Glu Pro Ile Gln Gln Glu Val Glu Arg Arg Glu Pro
                 320                 325                 330

 Glu Glu His Gln Val Glu Glu Glu His Arg Lys Ala Leu Glu Glu
                 335                 340                 345

 Glu Glu Met Glu Gln Val Gly Gln Ala Glu His Leu Glu Glu Glu
                 350                 355                 360

 His Asp Pro Ser Pro Glu Glu Gln Asp Arg Glu Trp Lys Glu Gln
                 365                 370                 375

 His Glu Gln Arg Glu Ala Ala Asn Leu Leu Glu Gly His Ala Arg
                 380                 385                 390

 Ala Glu Val Tyr Pro Ser Ala Lys Pro Met Ile Lys Phe Gln Ser
                 395                 400                 405

 Pro Tyr Glu Glu Gln Leu Glu Gln Gln Arg Leu Ala Val Gln Gln
                 410                 415                 420

 Val Glu Glu Ala Gln Gln Leu Arg Glu His Gln Glu Ala Leu His
                 425                 430                 435

 Gln Gln Arg Leu Gln Gly His Leu Leu Arg Gln Gln Glu Gln Gln
                 440                 445                 450

 Gln Gln Gln Val Ala Arg Glu Met Ala Leu Gln Arg Gln Ala Glu
                 455                 460                 465

 Leu Glu Glu Gly Arg Pro Gln His Gln Glu Gln Leu Arg Gln Gln
                 470                 475                 480

 Ala His Tyr Asp Ala Met Asp Asn Asp Ile Val Gln Gly Ala Glu
                 485                 490                 495

 Asp Gln Gly Ile Gln Gly Glu Glu Gly Ala Tyr Glu Arg Asp Asn
                 500                 505                 510

 Gln His Gln Asp Glu Ala Glu Gly Asp Pro Gly Asn Arg His Glu
                 515                 520                 525

 Pro Arg Glu Gln Gly Pro Arg Glu Ala Asp Pro Glu Ser Glu Ala
                 530                 535                 540

 Asp Arg Ala Ala Val Glu Asp Ile Asn Pro Ala Asp Asp Pro Asn
                 545                 550                 555

 Asn Gln Gly Glu Asp Glu Phe Glu Glu Ala Glu Gln Val Arg Glu
                 560                 565                 570

 Glu Asn Leu Pro Asp Glu Asn Glu Glu Gln Lys Gln Ser Asn Gln
                 575                 580                 585

 Lys Gln Glu Asn Thr Glu Val Glu Glu His Leu Val Met Ala Gly
                 590                 595                 600

 Asn Pro Asp Gln Gln Glu Asp Asn Val Asp Glu Gln Tyr Gln Glu
                 605                 610                 615

 Glu Ala Glu Glu Glu Val Gln Glu Asp Leu Thr Glu Glu Lys Lys
                 620                 625                 630

 Arg Glu Leu Glu His Asn Ala Glu Glu Thr Tyr Gly Glu Asn Asp
                 635                 640                 645

 Glu Asn Thr Asp Asp Lys Asn Asn Asp Gly Glu Glu Gln Glu Val
                 650                 655                 660

 Arg Asp Asp Asn Arg Pro Lys Gly Arg Glu Glu His Tyr Glu Glu
                 665                 670                 675

 Glu Glu Glu Glu Glu Glu Asp Gly Ala Ala Val Ala Glu Lys Ser
                 680                 685                 690

 His Arg Arg Ala Glu Met
                 695

<210> 5065
<211> 1294
<212> DNA
<213> Homo sapien

<400> 5065
 cgcggccttt cgggcgaaag ttaggagggg ccgggctggc gggcgggcgg 50

 gttccggggg ctcctttccg caccagcggc ggtcgctccc cgtgggcggg 100

 acctcgggcg tgatcgtcga ggagaccgcg gctccctcac ctgccggctt 150

 gttcctcggg gtccgcggag cgagcccagc tctcggcgcg tgtcggagtc 200

 tcccagcccc gcggccccga gcgcacgatg cgcggacccg ggcaccccct 250

 cctcctgggg ctgctgctgg tgctgggggc ggcggggcgc ggccgggggg 300

 gcgcggagcc ccgggagccg gcggacggac aggcgctgct gcggctggtg 350

 gtggaactcg tccaggagct gcggaagcac cactcggcgg agcacaaggg 400

 cctgcagctc ctcgggcggg actgcgccct gggccgcgcg gaggcggcgg 450

 ggctggggcc ttcgccggag cagcgagtgg aaattgttcc tcgagatctg 500

 aggatgaagg acaagtttct aaaacacctt acaggccctc tttattttag 550

 tccaaagtgc agcaaacact tccatagact ttatcacaac accagagact 600

 gcaccattcc tgcatactat aaaagatgcg ccaggcttct tacccggctg 650

 gctgtcagtc cagtgtgcat ggaggataag cagtgagcag accgtacagg 700

 agcagcacac caggagccat gagaagtgcc ttggaaacca acagggaaac 750

 agaactatct ttatacacat cccctcatgg acaagagatt tatttttgca 800

 gacagactct tccataagtc ctttgagttt tgtatgttgt tgacagtttg 850

 cagatatata ttcgataaat cagtgtactt gacagtgtta tctgtcactt 900

 atttaaaaaa aaaacacaaa aggaatgctc cacatttgac gtgtagtgct 950

 ataaaacaca gaatatttca ttgtcttcat taggtgaaat cgcaaaaaat 1000

 atttctttag aaacataagc agaatcttaa agtatatttt catataacat 1050

 aatttgatat tctgtattac tttcactgtt aaattctcag agtattattt 1100

 ggaacggcat gaaaaattaa aatttcggtc atgttttaga gacagtggag 1150

 tgtaaatctg tggctaattc tgttggtcgt ttgtattata aatgtaaaat 1200

 agtattccag ctattgtgca atatgtaaat agtgtaaata aacacaagta 1250

 ataaatgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1294

<210> 5066
<211> 182
<212> PRT
<213> Homo sapien

<400> 5066
 Ala Ala Phe Arg Ala Lys Val Arg Arg Gly Arg Ala Gly Gly Arg
   1               5                  10                  15

 Ala Gly Ser Gly Gly Ser Phe Pro His Gln Arg Arg Ser Leu Pro
                  20                  25                  30

 Val Gly Gly Thr Ser Gly Val Ile Val Glu Glu Thr Ala Ala Pro
                  35                  40                  45

 Ser Pro Ala Gly Leu Phe Leu Gly Val Arg Gly Ala Ser Pro Ala
                  50                  55                  60

 Leu Gly Ala Cys Arg Ser Leu Pro Ala Pro Arg Pro Arg Ala His
                  65                  70                  75

 Asp Ala Arg Thr Arg Ala Pro Pro Pro Pro Gly Ala Ala Ala Gly
                  80                  85                  90

 Ala Gly Gly Gly Gly Ala Arg Pro Gly Gly Arg Gly Ala Pro Gly
                  95                 100                 105

 Ala Gly Gly Arg Thr Gly Ala Ala Ala Ala Gly Gly Gly Thr Arg
                 110                 115                 120

 Pro Gly Ala Ala Glu Ala Pro Leu Gly Gly Ala Gln Gly Pro Ala
                 125                 130                 135

 Ala Pro Arg Ala Gly Leu Arg Pro Gly Pro Arg Gly Gly Gly Gly
                 140                 145                 150

 Ala Gly Ala Phe Ala Gly Ala Ala Ser Gly Asn Cys Ser Ser Arg
                 155                 160                 165

 Ser Glu Asp Glu Gly Gln Val Ser Lys Thr Pro Tyr Arg Pro Ser
                 170                 175                 180

 Leu Phe


<210> 5067
<211> 4988
<212> DNA
<213> Homo sapien

<400> 5067
 tacccagcac ctaatacctt ttaacataag tattgcatta agattttctc 50

 ttctctttgt agcttaggat ttcctggaag ctggctgtct atcagtgtgt 100

 gttaagtgtg atgcttccat aatacatttg gatgctgtca gctaagttca 150

 cttctgaact aaggggttcc tccaaatgtt ggctgaaatt catcccaagg 200

 ctggtctgca aagtctgcaa ttcataatgg agctactgta ctggctattg 250

 gaaggaggag attctgaaga taaggaggta atattatctc ttttaaaaga 300

 atactttcct ctgtaatcct gaatctttat tacatgtaag aactttgtgc 350

 agtagacagc aatttctttg aatttggtat atggaaacaa ttttattttc 400

 ctctgctaag tttttgagcc tgcctcttct agtgccatgg actgcattgg 450

 tagagctgag aaatatcatt tagccatact cagcaccctt aaaatagctt 500

 ctttctgaga attagatctg tgaaggtgtc ctgcacagtt cttgtagatg 550

 tcattttagt ttgtggttga cgtgcatgca tttagcatgt tgcttaaccg 600

 tcctcattcg cctcccagtt ctttgttgcc ttcatttggg gggatgtgtt 650

 ttctgctgga tgatttactg ctagacatga ccaaactctg agtataagac 700

 ttggtgtttg gcagctggtt ccagtgctct gctgagaagt agttgggccc 750

 agcctggggc attgtagtgt cctggaggcc gggagctcct gcacaggggt 800

 tcttttcctg gttcagagcc ttaggtgcct ttccactttt cacgtaatct 850

 tttcctaggt tggcttgctg cttactttgc agctgttgca gggattcaca 900

 tggaatggag ggctcccttt tattgtggat tatttctttg ataatttacc 950

 catgtgcttt ttcattttca aaaacccagt ggtgtttaag aatgaaagat 1000

 tcttgaagaa caaaaattgg gttaaatttg tatctatcag aaaagattct 1050

 atcctctgat gctatgtagg cacattgaat atgcaggcta aattaaaaac 1100

 agagtaaaac ctttttataa tatgccaatt actatatcta agaatgttta 1150

 tacaggctga aattttgtaa tggtatttat atctgttttc ctttttaagg 1200

 aaaataatat acttttctag gcatcaaaaa tatctgcccc tttcactaat 1250

 gctgatgtac cacttccccc aaccccaacg ctaaatttga ctggcttaaa 1300

 aacatctgcc ccctgaacta tatctgggga ggaatattaa taaaacaatg 1350

 aaggacttca tggtgtctag ttatataatt aggaaattgg ttagaaacgt 1400

 ggctaaaacc agtttctttc attaaaagaa ctagtgtaca tttaaaaaca 1450

 aaaacttcag gaaaaagact ctttgatctt taagtcaaat agtatttttg 1500

 gttaacacag caggaagggg aaatatacca atttcagatt cttttattta 1550

 tgcctaagta gaggttgtaa gcagctaagg aagtgattaa aatgtagtct 1600

 agtaaaaaat ggtgctgatt acttggaaag cagtttacat ttgcaaaaaa 1650

 attcagtatt atgaccttca ccaactttta cacatcatat acttgggtta 1700

 ttacttatgg tatagcttgt gtatggaatg caagggtatt ttcaaattga 1750

 ctaggtcttg ctggtcatct taaaatatgt tacaatatta caaaattgaa 1800

 atgtaatatt ttttaataga aggaaaatat aaatttaata tctgggcaat 1850

 tgagaccttt aaacttactt taaaagtatg atcttgatgt atatgatact 1900

 gttttgtctt tgctatatta acagaattag aggggtgttc tgcaattcaa 1950

 ataccttata tattccaaat tttattctct ataatggact tttaaaataa 2000

 aaggtatatg tgcttcaaga gggcaaaatt tgaatcatga gctaatttgc 2050

 taagcatcag attatagaaa agcatccttg attaatttgg aactgtgaaa 2100

 gggggcgggt aaaactgttt tctgcagaaa tttactagtg cagcaaccat 2150

 ttaaattaaa tgtttgttaa cataatagtg atggcatttt ctcctccccc 2200

 tccttgtggt ttgtccaact agatgttaca gtggcagttg cactgactgt 2250

 taagtgttta aatgatgaca ccattatgtg aagtgatttt gaaatgagag 2300

 attccagcca agaattacat ctgctcccat ctccttcaaa tcatactctc 2350

 tggcagtaca gattatgatt gatttgtttg tgacagattg caggaaacag 2400

 tcattgattt ttcaatattt taccttaaaa ttatttacag ttgtaaccat 2450

 ggggaggtat tttcatgggc tgtcagcccc tgaaagacta ggataatatt 2500

 ccctgctctc tgacaagaca aattacctgt aatgagtgca gtagctgaag 2550

 ggtatacttt tattttaaaa tatgtcaata accccagtga ctaaacgaat 2600

 attgatttag cataatgaag cctgagtaac gtgaaaatga gctttttcaa 2650

 ggggcatggt aaagtctttc tttttagctg gttgtaagaa gcttttgatt 2700

 cttttcagcc agctggtagg aatatagaat tttataagca aaccatcagg 2750

 aatgatagtg ttgtttctga taagcaacat ccaaatattt tgaccctgct 2800

 tttagtggtt tttttcaaat cttattttga gtcttacttt tagtcataga 2850

 atagctactg atttgatgcg gtctttaact gacttaatat ttttacaatt 2900

 tcaatatatt ttgcattgga atctccagta atgaatatta aaatatatgt 2950

 acaatcattt gtagatgata tcaattatat taagacattt cagatgggct 3000

 attgtagtat ttaatgtgcc gtattttatg gtagaataat tctcagtctc 3050

 tggacatcaa gattgctttc agtgggaatg aagattaatt tacttcagtc 3100

 ctgatttttt aggcatcaat gcatgttttc atttttgtca gacttttacc 3150

 ctcttttaat gtaattctca acttcttatg gatttacttc ccaatacata 3200

 aaatccttca aaacaagaat gataataatt tttatacttt ttataaaaat 3250

 aaatttattt ttagtccatc aaggtgtctg aagattttat gcctaggtat 3300

 ctccatatct aacttgataa ggaaaatagg ataaacaatg ctggtaatag 3350

 caggaaagta agtatttgaa taagatgtca aactgatatt tcatgtgaac 3400

 ctaactcatt ttatggtaac taataattat cttatttaaa tcaataggta 3450

 aaacctgttt agaaattaaa aatgagttac gatttaaaga aaattcagat 3500

 gactcattgt gagtgctagt tctcttgtag gatgccactg gaaatgttga 3550

 aatgaaaaat gtaagtatat cttttggtgg aaaaaaggat agtctctagg 3600

 acacaaaatt actgttttat ttttttctca ggagtttgcc taagggtgtg 3650

 acagatgatc tctgtcactt gtcttagttg tgtcctgcaa taaactggat 3700

 gctttataaa atactagacc tgtgatttcg tatgctgtaa tatttcattt 3750

 ctccatcacc cctccaaatt atttcttagt ttggagtaaa ataataaatg 3800

 tattatagtc aacatctctt gacccctctt tagtttcagc taaactaagc 3850

 atgtgtgttt gtgtgttcat tttatagttc atgtgtagaa ctatgtgaat 3900

 taaatttaag aaacatgtaa agtagaggaa atagttttct ggagaaattt 3950

 ttcctttttg gatattatgc ccttttccat tgcttttctc tgcttgaaag 4000

 caaaaaaaag taccctaccc ctgttctcct ttagggaaaa actattccta 4050

 taaagtattt ttaaatcgtg caagtcattg cctagggtta gctaaaacat 4100

 ttctttttaa aaaggagaaa atgccctggc tttaacattt tcttgtattt 4150

 gtatctatta agataaacag tttactttga tacagtacat accaatctac 4200

 ttaatttttt ttccaggatt ccttttacta tgtttggtct gaccttttat 4250

 gataacttaa tatgggaaca aattagcata taattctatt ttccatgtga 4300

 cctcaaccag ttgcagaatt gtaccactac tttagggggg gcaatttgac 4350

 agtttatgta gactatagca ttaattgttc ccaaatgttc agtgcatcct 4400

 ggctaatgtg ttattgaagg tgttttcacg taagcagtta gaggaagcac 4450

 ttcaccccta ttactaagtt attaaaatgc ctcctaaagg tagcatttta 4500

 aattagtata cataattgat tagtaatttg tcttctccca agcataaaac 4550

 agcatagcag agttaagtgt gaccagtgaa gtataagata ttagggattg 4600

 atggtgacaa tgatcatagc aactaaatgg attttttttt tcttttagat 4650

 tcagccgttg gtctttgaaa tttcctgtga tgtgtttcaa tctagatgca 4700

 aagaacatgg aaaaatcaaa gtgctcgagt ggtttaaata tgttttgggt 4750

 attcctgttt atagactata atacttttcc aattaaaatc ctcagttgtc 4800

 acgcagaaga aggttaagct gtatttgatt gccagtttta ctgaaaatgc 4850

 ttagtatttt acagtatcac caaatatatt ttgtttagcc aaggtatagg 4900

 aaaaataaaa taaattgtat aggttgactt ttttctaaaa tgtctttatt 4950

 ggattgaatg aatgtttata cctgaaaaaa aaaggttc 4988

<210> 5068
<211> 21
<212> PRT
<213> Homo sapien

<400> 5068
 Thr Gln His Leu Ile Pro Phe Asn Ile Ser Ile Ala Leu Arg Phe
   1               5                  10                  15

 Ser Leu Leu Phe Val Ala
                  20

<210> 5069
<211> 922
<212> DNA
<213> Homo sapien

<400> 5069
 gggaggagag gtgagccccc gcccgggcca ggccctctgg ccgcgccgtc 50

 cgcccctcta gtcgtgtccc ctcgtgggcc gaacggacgc ggcggtgccc 100

 cgcgcccgac cagacgtccc gtgggctagg gcctgggcct cgggccgcgt 150

 cggcgccggt cgagcctctc cgggtgtcgg ggttcggggc gggcgcgcgt 200

 gggcgtggct cctctgtcca cgcctgttcc cttcgtcgcc gcggctctcg 250

 tccgggacac ggctttccgg agtagagccc ttggaggtgt taagtgtgat 300

 gcttccataa tacatttgga tgctgtcagc taagttcact tctgaactaa 350

 ggggttcctc caaatgttgg ctgaaattca tcccaaggct ggtctgcaaa 400

 gtctgcaatt cataatggag ctactgtact ggctattgga aggaggagat 450

 tctgaagata aggaggtaaa acctgtttag aaattaaaaa tgagttacga 500

 tttaaagaaa attcagatga ctcattgtga gtgctagttc tcttgtagga 550

 tgccactgga aatgttgaaa tgaaaaatat tcagccgttg gtctttgaaa 600

 tttcctgtga tgtgtttcaa tctagatgca aagaacatgg aaaaatcaaa 650

 gtgctcgagt ggtttaaata tgttttgggt attcctgttt atagactata 700

 atacttttcc aattaaaatc ctcagttgtc acgcagaaga aggttaagct 750

 gtatttgatt gccagtttta ctgaaaatgc ttagtatttt acagtatcac 800

 caaatatatt ttgtttagcc aaggtatagg aaaaataaaa taaattgtat 850

 aggttgactt ttttctaaaa tgtcttatat tggattgaat gaatgtttat 900

 acctgaaaaa aaaaggttca aa 922

<210> 5070
<211> 42
<212> PRT
<213> Homo sapien

<400> 5070
 Gly Arg Arg Gly Glu Pro Pro Pro Gly Pro Gly Pro Leu Ala Ala
   1               5                  10                  15

 Pro Ser Ala Pro Leu Val Val Ser Pro Arg Gly Pro Asn Gly Arg
                  20                  25                  30

 Gly Gly Ala Pro Arg Pro Thr Arg Arg Pro Val Gly
                  35                  40

<210> 5071
<211> 863
<212> DNA
<213> Homo sapien

<400> 5071
 aggatgtagt gagctatggg agcacggagt gcactccagg tggatgacag 50

 aggtgggacc ctacctctat gagaaatgtt aaaatgtaga acattgataa 100

 aattaagtca gttattttaa tctgaagcca agaacatgta gaatgttatg 150

 attagagttt atcacatatt aatgtatact ggcaaattgt gttactggag 200

 tatacccata ggaggaataa attcaaacct gttttattta tttgaaccta 250

 tttacggtat gcttaagaat tgaatcagta taaattctca aatatgggag 300

 aaattttgtt cttgagaatt atctgagtca ttaatatttt tcaaaaacag 350

 ctctcactga cttgaacctc ttctgtaagc tctaaccttt tacctgcttt 400

 acatttccac ttgaatgtct agtaggcatc tcttgaccaa aaacagcttt 450

 tgattcctgt tctccaacct gttcctctcc tagttttctc catctcagaa 500

 atgttacttc ctctgcaaag tctttccctg acttatctaa aataataacc 550

 tcctctgttt gctgtgggaa tttgtataga atggtgggaa aatttcaagt 600

 ttcatatttg gattagctct gacatttatt tatctgaaca ctggtaattg 650

 cctcagtaaa gacactgata ataagtacct tttagagtta ttttaatctt 700

 taatgcttta atgtgtagga agagtatagt gtcctgtttt gcacagaaag 750

 gcattctgta aataataagt tgccttaatt ttcctgtaat gttcattata 800

 ttgttgtggg aaggtattta ctcctattat taaaaataaa aatgtgtaaa 850

 atttactacc tga 863

<210> 5072
<211> 26
<212> PRT
<213> Homo sapien

<400> 5072
 Gly Cys Ser Glu Leu Trp Glu His Gly Val His Ser Arg Trp Met
   1               5                  10                  15

 Thr Glu Val Gly Pro Tyr Leu Tyr Glu Lys Cys
                  20                  25

<210> 5073
<211> 958
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 348-475
<223> Unknown base

<400> 5073
 ttatgcaatt agggcttgct taattttggt aatttgtcta tcattttgtg 50

 tgcatatcag aagataaata tgtgcctttg gaaggcctta gcactattca 100

 cttggagttt ttacagaaaa tatttggggg tggccagcat acccagttgg 150

 tgttaatcct tgcttattat atccagtgcc ttgtagagtg cagtaatttc 200

 gttgaaaatc tgcttgtgaa tctttgatgt atacattatc caaaaataac 250

 ctgactttaa ggtcattgct atctggttta ggagtcacat gtttgagaat 300

 tctgggacta ttagcaccac acactttgta attttatatc agatgttnnn 350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 400

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 450

 nnnnnnnnnn nnnnnnnnnn nnnnncacac ccagcccaaa attatttttt 500

 ggcttacaaa agaagttgct ttaaacttct gtttcatctg taggatatgg 550

 ataacaatag ttaagagttg tgagaattag aagttagaga ccttactcag 600

 aatactaggg agcaggtgtt agggattttg gagctttacc ttttaagaac 650

 ttttgtccat atagtagaca acatactcac cagtgaggac ctcaaatagc 700

 aatatttctg tggtgaaatt tggggatatt tatgttaaat aaacagcatg 750

 tcagtcaagg ttgggttttc ctgacaaaat ttgaaagaat ttctctggat 800

 tttggttttc aggactggtg tgacttaaca tacatggcat agatagtata 850

 cgtctgttaa gtcagtaatt acacttactt gagcacaggt actgttcaag 900

 gtgctgagaa tacagtatag acaaattcct acccttatga agctgatgtt 950

 gcaaaaaa 958

<210> 5074
<211> 84
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 20-63
<223> unknown amino acid

<220>
<221> Unsure
<222> 348-475
<223> Unknown amino acid

<400> 5074
 Met Phe Glu Asn Ser Gly Thr Ile Ser Thr Thr His Phe Val Ile
   1               5                  10                  15

 Leu Tyr Gln Met Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa His Pro Ala Gln Asn Tyr Phe Leu Ala Tyr Lys Arg
                  65                  70                  75

 Ser Cys Phe Lys Leu Leu Phe His Leu
                  80

<210> 5075
<211> 2717
<212> DNA
<213> Homo sapien

<400> 5075
 ttttcccatc aagcgttact ttgattctgt tctgacctca ttccatagtt 50

 tgcagtgagc atggcatctt tgcctggaga tactatgcta ggggcagctt 100

 tccaggggca aagcaagccc tcgtgttaca cggctctcct ccagctcaca 150

 cgacatgtga ggagatgacc aaatgtgaaa acaggtttcc cctgtgttgc 200

 ccgtcatcct ttggcccgtt cacaggaatg gagtactgta taattttagg 250

 ctttcattcc cagcagtgtt tactgaggac ctggttttct agaacaggtg 300

 tgtcctgtcc tcttccatgt tccctggggg ctggtcagct ccaagttgtg 350

 ggtggcagag ctgtgtttca gcatgaactg actagagacc catctggagg 400

 caaatattaa gttgccagga ctgctttcac ttcagggtga ttgaaggaca 450

 catattgaag tacctagaat gccagaaagt gttctattgc ccaaaaaaca 500

 aatcagaaaa gcctattctt ttttgcaacg ctgttaatga ttagtggagt 550

 tctgaaatta ctttgtgcca cttggaagta ctgtgaaacc gcattcactg 600

 ggattttgct gtaattcaca tccgctggac tgaagtttac cttgatgtta 650

 gctataagaa atagttttct aacacatacg atagcaaata caagacaaat 700

 agcattgaag gccaacaaaa atggcttcag atacacctta gctataatgt 750

 ttgcattcaa acaatgaatg tattcatcac aagtcactta ccaaagcact 800

 tctagacttc tccaacctcc atgactttgc tctgcttcct cctgtccctg 850

 tcagcagggt tgctgtttgt acttgaaggt aataaacctg taatccttca 900

 aaaatgccat ttagccccag gcttctgagc tgagtcagac tgacccatcc 950

 caccgttagg gcaaaagtca ggctgggaca cagcgccagt acagagagga 1000

 tcctgccttc atgcaactcc ccttttggag ttaatgcagc gtgatttcct 1050

 gggccggtgt tttcaggcat cgccccaccc ccaggtatgc tggttcccag 1100

 ctccacgtag gtgtgcctat cacgctgggc cactttgctg acaacattca 1150

 tagcttgaca tgagagagaa tatcagcaga agcatgagag taggacctga 1200

 cgtctttgac tctgcaaaag catttagcac acactcatgg gggggaactg 1250

 gctgtgagcc acagcagccc cacacagaca gtggtctctg aacttcagga 1300

 aagccatgga cagaaaaaaa aataaaattc ttttccatca ttctattttc 1350

 aaagaggtct tggcgttttc ctacatcttt tgtttagagg ggaaaaaaag 1400

 gtttcatttg ctgccatttc agaaaggtta tgctatcctg ttttttccaa 1450

 gcagttgtga gtcaggaact gcctgggcag tgtgcatcaa ctttgtggcc 1500

 gaaccattac agctgtcata tccttggctg atcgtctctc ccagggacta 1550

 ctgccctcca cttagtgtct gagggtaagc ctagaagggt gctgctattg 1600

 ggtctatgga agcttatcta tcaaaggagc aaacatccag aaaagtgttt 1650

 ataaagcaaa tgtattgcct ctgtttagag atttgcccag ctgttccagt 1700

 tttaaacatt aaaaaataaa ctcagttgcc atggcaaaaa tagaatgcac 1750

 agcttactta taattttcca tgcagtatag cataaggatt tttgacttga 1800

 aacaaccaaa gaactcctcc ttaacgagac agttcaaatt cctgaattag 1850

 tatttcttga ctatcaactt aaagaatgga cttcctagta caatgttgca 1900

 cttatttttt tttctgaaat aattctgcct gcatgtatgt gttgtgtttt 1950

 agcttctccc cttaccccac cccaaagatc ttttcttcct aatggttaat 2000

 gtctcaactc ggttactgtt tactatcaga tggtttttca ttagtgaatt 2050

 tagacctctt tgagaaagct tgtatataaa aagttaacag atatatttta 2100

 tggaaaaacc catcttattt tcaaatatat ttaactgctg ttatatttta 2150

 ttagaggaag gttgtaaata ttttctagga gttctattgt aaagaaaagt 2200

 atttttgaaa aaaattaatg taataaaaag gaaaacattt ttaaatagtg 2250

 gttgtgattg cttcctgttc tggcttcgtt atgttctatt ctcagcagat 2300

 gaattgcatg ccttccatat caggatgtaa tttattcagg tttgcactat 2350

 tataagttga catcataata tctagtgtgc ttaactgtat tttcccggaa 2400

 tgcaagtccc ttggtccata ttaaagcact atgtatagca tattcataat 2450

 ttttcttttg taacgtgtgt atttttaata aggattttat gtaacatttt 2500

 ggcaacaaga ggaccgtatt ttctagtgaa ttttataata acattttgct 2550

 aaaaatgttt cttcctaggt cagtttttgt taaggtgaac caaaagtctt 2600

 attttaccag gggtttaaaa aaagtttgaa gcttgaaagc aaagttatat 2650

 ttaaacatca tatgtaacaa ataaataaag atgttttata gacttgtcct 2700

 aaaaaggtgc attcctt 2717

<210> 5076
<211> 11
<212> PRT
<213> Homo sapien

<400> 5076
 Met Phe Tyr Arg Leu Val Leu Lys Arg Cys Ile
   1               5                  10

<210> 5077
<211> 1081
<212> DNA
<213> Homo sapien

<400> 5077
 gaccgctgac ctagagggag ttatgcacat gggcttataa ggttagccaa 50

 gagaaaggac aagaagaccc aaagtcggca agcaaattta ttaacctgct 100

 gggctgctct acagaaatct gaggaggcag acaccgggct tacaggctaa 150

 ggggtataag taggtctgca ggggttttgt gtgtgtgtgc gggggtgtcg 200

 ggggggcaag gccatttgtg gagacttttc ctcccagtat ggccacatcc 250

 tgcagtttgt cagtttttgc ccccgcctgg ctcagggtac caggatgtgg 300

 tttagcttag gggtggttat agtggcacct aagttctggg aacttgcggt 350

 gggggcgacc ttttggacga aaaataagct gcagggcagc taggggaggg 400

 ggcttgttat attcctctgg gggcagggtg tccctaactg ggctcagtcg 450

 gaaggaactt gaccaaagtc tgggctcagt tgggcatcac tcaggctaat 500

 ggtcgtgtgc tggatgccat cagagggaag taccaatggt aaagtggaaa 550

 caatgtgcag ctttcaactg ggtggaggct gctattctgt ggacagtgag 600

 atgtttcctt ggcactgtca atagacaatc tgcgtagaga aattccaagc 650

 tgaaagccaa taatgttata ataaaataga gattcttcag aagatgaaag 700

 gaattaccag catggaaatt gtgtcatagg cttaagggct aaagaagaag 750

 ccttttcttt tctgttcacc ctcaccaaga gcacaactta aatagggcat 800

 tttataacct gaacacaatt tatattggac ttaattatta tgtgtaatat 850

 gtttataatc ctttagatct tataaatatg tggtataagg aatgccatat 900

 aatgtgccaa aaatctgagt gcatttaatt taatgcttgc ttatagtgct 950

 aaagttaaat gatcttaatt ctttgcaatt atatatgaaa aatgactgat 1000

 ttttcttaaa atatgtaact tatataaata tatctgtttg tacagatttt 1050

 aaccataaaa acatttttgg aaaaccataa a 1081

<210> 5078
<211> 12
<212> PRT
<213> Homo sapien

<400> 5078
 Thr Ala Asp Leu Glu Gly Val Met His Met Gly Leu
   1               5                  10

<210> 5079
<211> 2377
<212> DNA
<213> Homo sapien

<400> 5079
 cttcagactc aagactgcaa caccgtgcct gccctctagc tatgctttaa 50

 ggcaggccta tcagcccaga ctggagtcat gtaatacatg gctctgtcag 100

 tagctctcct tcccacaaat aagttttgat gatcttacac tcatccctgc 150

 cgttagcatt caggaccaat cttctatagc ctatacgcca cactggtcta 200

 ggacagcacc taaataatac tcatgctata aaaaattcat caagttatat 250

 atttttaaaa acatccctaa aattatcttt ttcctttact gaaaagaatt 300

 tcaggatccc ctctctctca ctgcctctct tcacacacac ctaccttagt 350

 tggtcaccta ttttgtaaac atatcttctt taaaaaaaga aagaaatggc 400

 agtacatgaa aaactgcttc gtaaacagaa actatattat ttatatttgt 450

 agcatttttt tccccttgag gttaatttcc tttgcttccc ataactggaa 500

 gccaatgatt cagtgccatt atataagctt attttccctc ttggaaatag 550

 taaattataa gaggtttgac ccaaaaatat acatcaaaat taggcagtat 600

 tcggtgttta gcctccatct gccttgtctt cttgtcttta gttgtgcaag 650

 tagatgctga tgatttctgg cagagctaaa gtaagtaaat catgtgaatt 700

 tatttttttt cctcataaaa cagatggcat ggtctagctc tgggcttgta 750

 tgtttcatga agtacatggg tctgagtgcg tatttatttt gtgagccaag 800

 gtttatgcct tcttctataa ttttctttca ccgaaaatta cctggagagc 850

 tagaaactcc atttgtgtca gcgtaagaag ctttagaatc tatatccaga 900

 ccaaggccat ggaacaatgt agattcactc agtaaaaact cactagcggc 950

 cttctttgta ctagtctgtc acctttgctt ggctttggga agcttcaaac 1000

 tagggcagtt tatgtttggg agtgaccagt caaatagcaa gacagacata 1050

 ggcaaggatg taatttttaa aaatttaagt ggggaatggt gaagcatgaa 1100

 tcaaaacaga aggtagtctt accttcttgg aactgtaaaa taaatacatt 1150

 tgaaaaaggc accctctcaa ccttctgcga gtcagaattt ttgctgccac 1200

 ccctcatttt gaatctctat tctgcatttt ttattctttt ttttaggaag 1250

 gaggaagaaa aatttctcct gaagaattca ttggaaatta aaattaactt 1300

 gcgtattttg tattctttgg aatgtgatga agactgattt gaaagggcag 1350

 tgctggattt ggtcaggcat aggaaaggaa gacatgcagt cgtcctgcct 1400

 agctcatccc cgccacgatg gagaagtggg gttgctttcg ttgtactttt 1450

 tttcatttgt ttcttgccaa gcccagtggc ttctgttata acatgtggca 1500

 gcttctccct tggagactga ttcagtccaa gttaccataa tatttaggac 1550

 cagctacaga gacgtttctt cccctaaacc catgccaaat ctaaatcaaa 1600

 ctatcttctt ctccttagcc gttcaaatag ctccagctct tatataaaaa 1650

 tacgagaaat acacaggcct cttttcgttt tattcctgtt caaacagata 1700

 aacaaacaag gcacatcatg cctaggttgc tttgagcttg atcacttcct 1750

 cctaaagcag tcttacgctg tgttgatttt aagaattgca acttaggtgt 1800

 tctagaacat attctgagag catagtcata gtctgtgatc tcagaatatg 1850

 tttgcttcct tctagaacat ctgagttcta gaaattgcgt acaataaact 1900

 gctgtcagtg ctgctggagg aaggaagagt aactctgaca tcactggcct 1950

 tcaacaggtg tggcgctgag cttctgggcc tcagaagccc tgacttctag 2000

 aggctggggg ccagcggggc agggaggtga tctcatcatg gatggccaca 2050

 gatcatccac ctgccaaaca gttaaccctg aacaagtcat gtcaatttat 2100

 tttgctttta aaaaagaaag tctgcaaaat agaaaaaaaa aaaaagattc 2150

 ttcataaata catttgttct gatctgtaaa taccctggtc atttccccct 2200

 tggcatttga tacacatagt atagacatat tttagtcatc cttgctcaag 2250

 taattatatt ccataaccaa ctttattagc ataaattaac ttcctcatat 2300

 ttttagcaag agttactttc cttcattgct tagcttattg ttttgaaata 2350

 tgaattactt cagcacagtt cattttt 2377

<210> 5080
<211> 33
<212> PRT
<213> Homo sapien

<400> 5080
 Phe Arg Leu Lys Thr Ala Thr Pro Cys Leu Pro Ser Ser Tyr Ala
   1               5                  10                  15

 Leu Arg Gln Ala Tyr Gln Pro Arg Leu Glu Ser Cys Asn Thr Trp
                  20                  25                  30

 Leu Cys Gln


<210> 5081
<211> 4126
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2006, 4009-4054
<223> Unknown base

<400> 5081
 cctaccaccc tgggcagccg agcagagtcg tccccagcgg gtctccctcc 50

 ctgcctccct gactttgcaa caccgcgttc cgggaggacc ggcctcggcg 100

 agggaggagg cgggggagct gcgaacaccc agacccaaac cctggcagcc 150

 gcgagccgag gttggaggcg cccggggctg cttcgccctc cggctccgag 200

 cgccgggctc cgggcgccct gccctgcgcc tgggcagcag ccttgctggt 250

 cttgggggcg ccccccgctt cccgccccgg gggtccgcgg ccggcaggac 300

 catgctgctg aaagagtacc ggatctgcat gccgctcacc gtagacgagt 350

 acaaaattgg acagctgtac atgatcagca aacacagcca tgaacagagt 400

 gaccggggag aaggggtgga ggtcgtccag aatgagccct ttgaggaccc 450

 tcaccatggc aatgggcagt tcaccgagaa gcgggtgtat ctcaacagca 500

 aactgcctag ttgggctaga gctgttgtcc ccaaaatatt ttatgtgaca 550

 gagaaggctt ggaactatta tccctacaca attacagaat acacatgttc 600

 ctttctgccg aaattctcca ttcatataga aaccaagtat gaggacaaca 650

 aaggaagcaa tgacaccatt ttcgacaatg aagccaaaga cgtggagaga 700

 gaagtttgct ttattgatat tgcctgcgat gaaattccag agcgctacta 750

 caaagaatct gaggatccta agcacttcaa gtcagagaag acaggacggg 800

 gacagttgag ggaaggctgg agagatagtc atcagcctat catgtgctcc 850

 tacaagctgg tgactgtgaa gtttgaggtc tgggggcttc agaccagagt 900

 ggaacaattt gtacacaagg tggtccgaga cattctgctg attggacata 950

 gacaggcttt tgcatgggtt gatgagtggt atgacatgac aatggatgaa 1000

 gtccgagaat ttgaacgagc cactcaggaa gccaccaaca agaaaatcgg 1050

 cattttccca cctgcaattt ctatctccag catccccctg ctgccttctt 1100

 ccgtccgcag tgcgccttct agtgctccat ccacccctct ctccacagac 1150

 gcacccgaat ttctgtccgt tcccaaagat cggccccgga aaaagtctgc 1200

 cccagaaact ctcacacttc cagaccctga gaaaaaagcc accctgaatt 1250

 tacccggcat gcactcttca gataagccat gtcggcccaa atctgagtaa 1300

 ctttatataa atatctcatg gggttttata ttttcatttg ttgttgttgt 1350

 ttttttttaa gaatcttctg atagagaaaa agactgcttt gtcactcaaa 1400

 catgttcctt cgacctttca gtgtgcatgt gactcagtaa cttcacatag 1450

 aatatgattc cctaagtatg ctacacagca tcatattaga tgtaagatgt 1500

 aagacttgca aaggacagaa ggaatcttct gtaaccacat agctgtatgc 1550

 cagagaggaa gccttgttat tgggcatttg atgaggtttg gcatggactt 1600

 caaggataaa tgaatgaaaa ctttgcacca cttttgttac aaggtacggt 1650

 agaaaatagt gaagtcagtt tcctctcatc aaatctaaaa ttctccaaaa 1700

 tactctcagg cataacatac ttagctgtta aattttgaac tgctaattac 1750

 taatacttga ataccaatag ttactgagat tcctattttg tggttagtct 1800

 gactcaggat ttggagccta attaactcta aacttttgaa aattttaatc 1850

 atcaagctat agaggctcca agtgcaatta ataataactc atttatacct 1900

 tccacagaat ttaataaaga ttctacttgt ttctgtcttt taataacttt 1950

 ccccttttgt gcccttgtgg cctcagaaat ccttaagaat tgcatggatg 2000

 aatgtnacca taactgattt gggaatggtt cagtttagga accaagaggc 2050

 ccaggtgagg caacatcttt tttctctaca ggtaccaaca aaccttgact 2100

 tgtcagcttc catcatcaat taagattctc agaatttgca attaattgaa 2150

 tagaattcat ttactatctg cccactcaaa gaagtacaag ggtagagtaa 2200

 gctaactggg ctttaacatg gtcagaatgt ctggtgcatg aactataaaa 2250

 aagagaactg tctcccatcc ccttccttgt tttactctta gtaacatcca 2300

 gaattccctg gaacagattg cctaccacca gaccttagaa aagactgtca 2350

 ttctcttgct ccttacttga aatacaaata ttgggaatgt cacagacatc 2400

 aagcaactac tgtcaagtgg gaggagagaa tgagcagaat tgctgactcc 2450

 tatttgtaga gtgaaaagga ggagtgataa tagatgccct tctgtctagc 2500

 tttcctttct tcaactagtg gtaatgcaag attagaatca aggttgacag 2550

 gaggcaagat cactcactga agtgacagaa agacaattct cctttgctcc 2600

 aaagagagaa atctgtcacc tttgcacctc actgccttta aacacagacg 2650

 ggagggcagg ccaaatctca gcattgactt ttgtcctcca agagaggaag 2700

 agaagaagta attgggcaac ttggaggccc gcgccccagc tagccttcct 2750

 gatcgtaacc tccaacctca ggaaagggac cttcccaaaa cacagatccc 2800

 aaaggaaaca aaatagacca aggagcataa tctgcttctc tcacacagcc 2850

 tctctgccag tggaccctgc ctgcttccct ctcagtgctc agcactctgt 2900

 gtagtgtctt tcaggttgat acactctccc aaggtgcagg cgctggcccc 2950

 atgagcccag caccaaagtt ttctaagtca taggtcagac tgtcaagatc 3000

 atttctttat ctataggttg atatttagct taaaaaaaaa gaataaacct 3050

 agaactcaaa ggaaacctgt tgcaaatagc ttagatcaac agtgtatctc 3100

 ttccctaaga atgatagtat cttagtaaga caccttctat gcatggtatg 3150

 gaagcatgat ttttgcttgt gggaaaacct aatattttat cagacccctc 3200

 ggacttctca atccctccct ctccacacag tagtacttaa tgaaaatgtt 3250

 ttgctttaga gagcaaaatg ctactttcag aagacactga aatagtatat 3300

 gtatttgctt accatttgca agctaaaatc aaggtgggat ggggtcatta 3350

 ttttcacata gaatgtattt attttgtgca ggctgttaaa cacatctggc 3400

 acctagtttt tccattaaga gcattgctat tttccctttt tataaagtag 3450

 cttctgctgt caaggttaac aattctatat gctttaggaa gctaagttct 3500

 aatttccttt tgtgagtttc atttctttta taaccagtat gttaccacag 3550

 acatcagttg caaagctacg atgatagtgt gattcttagc cgaaaaaaaa 3600

 gcgtgtgctc ttaaagtatg ttcagttttt ctgtctacat atgctttgtg 3650

 tgagttaaaa agggggtggg tggtgtaaat attcctttag ctgctttgca 3700

 tatttaaccc agtcatcaaa aggcataaat gacttcaata ttttatatat 3750

 cttggttttc aagtatcatt tcacattctc tatacatgac tttgttattg 3800

 tggaatacaa gcctgcaatg gatgtatata tacagaacat taataattct 3850

 tagaaggatg gaagccaaat ggctgcatga tggaaattag aagaaaaaaa 3900

 aagcagaaac ttgaatttgc taagcatgtt tggggggaaa tagaatcctt 3950

 aactcagtgc ctctgtctgc gatatggaaa ccttcaactt tgttcaccaa 4000

 aattgtatnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 4050

 nnnngtatag tgaatcagac accatcagtt ttaagtctct ggtagccaaa 4100

 cttaaataaa taatccatag aatatc 4126

<210> 5082
<211> 432
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 2006, 4009-4054
<223> Unknown amino acid

<400> 5082
 Leu Pro Pro Trp Ala Ala Glu Gln Ser Arg Pro Gln Arg Val Ser
   1               5                  10                  15

 Leu Pro Ala Ser Leu Thr Leu Gln His Arg Val Pro Gly Gly Pro
                  20                  25                  30

 Ala Ser Ala Arg Glu Glu Ala Gly Glu Leu Arg Thr Pro Arg Pro
                  35                  40                  45

 Lys Pro Trp Gln Pro Arg Ala Glu Val Gly Gly Ala Arg Gly Cys
                  50                  55                  60

 Phe Ala Leu Arg Leu Arg Ala Pro Gly Ser Gly Arg Pro Ala Leu
                  65                  70                  75

 Arg Leu Gly Ser Ser Leu Ala Gly Leu Gly Gly Ala Pro Arg Phe
                  80                  85                  90

 Pro Pro Arg Gly Ser Ala Ala Gly Arg Thr Met Leu Leu Lys Glu
                  95                 100                 105

 Tyr Arg Ile Cys Met Pro Leu Thr Val Asp Glu Tyr Lys Ile Gly
                 110                 115                 120

 Gln Leu Tyr Met Ile Ser Lys His Ser His Glu Gln Ser Asp Arg
                 125                 130                 135

 Gly Glu Gly Val Glu Val Val Gln Asn Glu Pro Phe Glu Asp Pro
                 140                 145                 150

 His His Gly Asn Gly Gln Phe Thr Glu Lys Arg Val Tyr Leu Asn
                 155                 160                 165

 Ser Lys Leu Pro Ser Trp Ala Arg Ala Val Val Pro Lys Ile Phe
                 170                 175                 180

 Tyr Val Thr Glu Lys Ala Trp Asn Tyr Tyr Pro Tyr Thr Ile Thr
                 185                 190                 195

 Glu Tyr Thr Cys Ser Phe Leu Pro Lys Phe Ser Ile His Ile Glu
                 200                 205                 210

 Thr Lys Tyr Glu Asp Asn Lys Gly Ser Asn Asp Thr Ile Phe Asp
                 215                 220                 225

 Asn Glu Ala Lys Asp Val Glu Arg Glu Val Cys Phe Ile Asp Ile
                 230                 235                 240

 Ala Cys Asp Glu Ile Pro Glu Arg Tyr Tyr Lys Glu Ser Glu Asp
                 245                 250                 255

 Pro Lys His Phe Lys Ser Glu Lys Thr Gly Arg Gly Gln Leu Arg
                 260                 265                 270

 Glu Gly Trp Arg Asp Ser His Gln Pro Ile Met Cys Ser Tyr Lys
                 275                 280                 285

 Leu Val Thr Val Lys Phe Glu Val Trp Gly Leu Gln Thr Arg Val
                 290                 295                 300

 Glu Gln Phe Val His Lys Val Val Arg Asp Ile Leu Leu Ile Gly
                 305                 310                 315

 His Arg Gln Ala Phe Ala Trp Val Asp Glu Trp Tyr Asp Met Thr
                 320                 325                 330

 Met Asp Glu Val Arg Glu Phe Glu Arg Ala Thr Gln Glu Ala Thr
                 335                 340                 345

 Asn Lys Lys Ile Gly Ile Phe Pro Pro Ala Ile Ser Ile Ser Ser
                 350                 355                 360

 Ile Pro Leu Leu Pro Ser Ser Val Arg Ser Ala Pro Ser Ser Ala
                 365                 370                 375

 Pro Ser Thr Pro Leu Ser Thr Asp Ala Pro Glu Phe Leu Ser Val
                 380                 385                 390

 Pro Lys Asp Arg Pro Arg Lys Lys Ser Ala Pro Glu Thr Leu Thr
                 395                 400                 405

 Leu Pro Asp Pro Glu Lys Lys Ala Thr Leu Asn Leu Pro Gly Met
                 410                 415                 420

 His Ser Ser Asp Lys Pro Cys Arg Pro Lys Ser Glu
                 425                 430

<210> 5083
<211> 633
<212> DNA
<213> Homo sapien

<400> 5083
 cggacgcgtg ggtccttaga cttcctagta ttatggtggt tatagtgaaa 50

 gagcagtcaa actgtgtgag ttccgaaata aaggaaagtg ttatattcta 100

 cagtgcccat attttctatg gtaactaaat caaatatttg taagttcctc 150

 tgctttttga aattattttt caaagaagca acacctgtta tacaacagaa 200

 ttgtataaac taaaaagact tttggccttg gtacatagtc tttatctggc 250

 ctgcaatgga gtcatggttc tttctgaatc ccactctcac ttttttcttt 300

 ttacccttag atattgcatc cgtggtattt caggggtata gagaaataat 350

 attggaattt aggagctatt tttttaagtg aaaatattac taagtggtat 400

 cttttgatga ttacctactt taatgtgtct tagaaaagca ccaaaacata 450

 gcatgattat tttttcagtt aattaaaatt agttaataac atgttcattt 500

 aaaaactatt cattgacttt ttgtaccagt catatgcagg gtacagtaac 550

 tgaggatatg ggaaataaaa taactgacat agtccctgct ctgaaggaac 600

 aaaggaaaag gaattgcaaa tttttattac aat 633

<210> 5084
<211> 41
<212> PRT
<213> Homo sapien

<400> 5084
 Asp Ala Trp Val Leu Arg Leu Pro Ser Ile Met Val Val Ile Val
   1               5                  10                  15

 Lys Glu Gln Ser Asn Cys Val Ser Ser Glu Ile Lys Glu Ser Val
                  20                  25                  30

 Ile Phe Tyr Ser Ala His Ile Phe Tyr Gly Asn
                  35                  40

<210> 5085
<211> 1331
<212> DNA
<213> Homo sapien

<400> 5085
 atattatata tatatgtcta taacatatag acagagaaga taataatata 50

 ttcattttat agtttaggaa acagacttgg aagggcaaat aacttgtcta 100

 agatgactaa gcagctgagt gagaaccaca gcctatctgt ggcattcagt 150

 ttcagccatc tttcccttgc ttcataagga tagttactct ggtatcagtt 200

 gctggattgg gattttgggc atttataaat gtttttattt tggatattac 250

 tgaatcacag acaatttcat cttagttaat taaaaattca tcttacgtga 300

 cacttgtcta aatcttaaaa tattaaaatt ttaatgtata aggatgttaa 350

 taatctttat attttaagag actatgaagt caagtctagc taacttagat 400

 ctgtaagttt ttagctatgg aaagcaattc tattgtgtac aagtttcagc 450

 ctgtgaaggg aattcattga aaatgtatag agatcagaag aactaacacc 500

 tttcttgcat ggatttttct tgattattgg cagttaacaa taaaatgtta 550

 ttagatcact ggtgcttctg tgtggggttg agttttttat gatatcttct 600

 gttagaccca taagggaggc tgtgagttgt tttctacatc cttggaatat 650

 ataagatcct cttttaaaat tatattttat ataagcacat gaaaatggaa 700

 tgaaataatg aattgacata ggaattacct acatattttg gctgtacatt 750

 tagtgcacaa aatatccctt ttttgaatgc caaatggcca agtgtgaaaa 800

 ccaatatttg ttaaagctgg agcagaagtc ggtatcatca tcatagagta 850

 aacttctggc atatgtgaag atatgaaatg ttatccctga agttattata 900

 atttattctc agaaatatta gtaatcttat tttaagagta ggacattata 950

 gtgcagtaat gataattttc tcagtgctgc ctgttgctag attgttccta 1000

 tgattgctgt catgcacata cagacactaa attgagggtc actttccact 1050

 gaagttagtg gaatacaaaa taggtggagg aactttcttc ctctaacgtc 1100

 tttatatgtg tctgtgttta tatatacgtg tatgtatata aatatgtata 1150

 cacatatata atatctggag caaaaatgat tatgttgtaa gaacttttgg 1200

 aggttttcct cctcgtaaaa ttccgaagtg gtagagttaa cattctgctt 1250

 ttaatttatc tacaaaaaca tgtgaagaat ccccaaataa gattttctca 1300

 tagaagattc atggattttg agtctcagaa a 1331

<210> 5086
<211> 6
<212> PRT
<213> Homo sapien

<400> 5086
 Met Asp Phe Glu Ser Gln
   1               5

<210> 5087
<211> 1201
<212> DNA
<213> Homo sapien

<400> 5087
 atcaaaactt catgctgtac aacataaata tactatacaa tttttacttg 50

 tcaattaaaa aagtaatcct aacatttaaa aaggcaatgc ataaaaactg 100

 agaacagact ataacaactg aaacaaactg ggcaaacatg agatgagaaa 150

 ccagccagca agtcaatcag aactctttct tcatctcgtc tacaatattt 200

 tgtatttata actgtaaatt agtgtatagt gtttcactcc agagacttca 250

 ataatacagt gttatcatag gacttgtaca gatttcagag aaagacacat 300

 ttagaagatg gagagttctc cgttatgttc tatctgagag tcagtatgaa 350

 atgtcaaatc taaaagtaca taattcagag gtctatttca aattaataat 400

 catttgagca taatttctcc actgtcagag acgactgtta ttttattttc 450

 aatcaaatta aaagttgttt ttatgcatat cttattttta gttatatgtt 500

 acttgtacat acgtagcagt acaagtgcat ataaatcctg taagagtata 550

 aatcctatag aaatatatta agctgataat tatgtctgtt ctgtttgatc 600

 acagagttgc aacaaatagg cctcatttcc taagttgagg aaatgatttt 650

 ctcattttat atgagacttg tggtgtggaa tttcaaggta gaaccaaaat 700

 gtgtggaatg aatatttcaa tgaagatgcg ttctgctgct aatagcagga 750

 aatcccatct agtggcttta tttttcttta acccgttatc tcacatagcc 800

 gatagatcca aggctgggca tctccagagt tgctcaactc agcaggccag 850

 tggcatcacc agcgaccctg gaacttcata gctcatctct ctatcacaca 900

 cagtatgtca gctttcctga gatggtaggg tgacccctgc agcagcttta 950

 ggtttgttat tctttcacaa caactcccaa aggcaggaaa aggatactcc 1000

 tttctcctgt gtgcctttat aaggagcaac taaactgttt ccagagtgtt 1050

 cccagtaccc actttctcac acattggaat gaccgtggga tcacatgggc 1100

 tcagacaagc caggattcaa cctttgcaga gtgggcctga ggcacatggg 1150

 aagaaaagga gcaaaatcat gtattttaaa aaataaagaa atggtggatg 1200

 g 1201

<210> 5088
<211> 35
<212> PRT
<213> Homo sapien

<400> 5088
 Met Gly Ser Asp Lys Pro Gly Phe Asn Leu Cys Arg Val Gly Leu
   1               5                  10                  15

 Arg His Met Gly Arg Lys Gly Ala Lys Ser Cys Ile Leu Lys Asn
                  20                  25                  30

 Lys Glu Met Val Asp
                  35

<210> 5089
<211> 1044
<212> DNA
<213> Homo sapien

<400> 5089
 gtcttggtta ttcttggttc tttattattc aatataaatt ttagaagctg 50

 aatttgaaaa gatttggatt ggaatttcat taaatctaca ggtcaattta 100

 gggagagttg ataattttac agaattgagt catctggtgt tccaataaga 150

 ataagagaac aattattggc tgtacaattc ttgccaaata gtaggcaaag 200

 caaagcttag gaagtatact ggtgccattt caggaacaaa gctaggtgcg 250

 aatatttttg tctttctgaa tcatgatgct gtaagttcta aagtgatttc 300

 tcctcttggc tttggacaca tggtgtttaa ttacctactg ctgactatcc 350

 acaaacagaa agagactggt catgccccac agggttgggg tatccaagat 400

 aatggagcga ggctctcatg tgtcctaggt tacacaccga aaatccacag 450

 tttattctgt gaagaaagga ggctatgttt atgatacaga ctgtgatatt 500

 tttatcatag cctattctgg tatcatgtgc aaaagctata aatgaaaaac 550

 acaggaactt ggcatgtgag tcattgctcc ccctaaatga caattaataa 600

 ggaaggaaca ttgagacaga ataaaatgat ccccttctgg gtttaattta 650

 gaaagttcca taattaggtt taatagaaat aaatgtaaat ttctatgatt 700

 aaaaataaat tagcacattt agggatacac aaattataaa tcattttcta 750

 aatgctaaaa acaagctcag gtttttttca gaagaaagtt ttaatttttt 800

 ttctttagtg gaagatatca ctctgacgga aagttttgat gtgaggggcg 850

 gatgactata aagtgggcat cttcccccac aggaagatgt ttccatctgt 900

 gggtgagagg tgcccaccgc agctagggca ggttacatgt gccctgtgtg 950

 tggtaggact tggagagtga tctttatcaa cgtttttatt taaaagacta 1000

 tctaataaaa cacaaaacta tgatgttcac aggaaaaaaa gaat 1044

<210> 5090
<211> 7
<212> PRT
<213> Homo sapien

<400> 5090
 Met Phe Thr Gly Lys Lys Glu
   1               5

<210> 5091
<211> 10434
<212> DNA
<213> Homo sapien

<400> 5091
 atggcgaacc ggcgagtggg gcgaggctgc tgggaagtga gcccgaccga 50

 gcggaggccg cccgcggggc tgcggggccc cgcggccgag gaggaggcgt 100

 cttccccgcc ggtcctgtct ctcagccact tctgcaggtc tcctttcctt 150

 tgcttcgggg acgttctcct gggagcctca cggacgctgt ctctggccct 200

 agacaaccct aacgaggagg tggcagaagt gaagatctcc cacttcccgg 250

 ccgcggacct gggcttcagt gtgtcgcagc gctgtttcgt gttgcagcct 300

 aaagagaaaa ttgttatttc tgttaactgg acaccactca aagaaggccg 350

 agtaagagag attatgacat ttcttgtaaa tgatgttctg aaacaccaag 400

 ctatattact aggaaatgca gaagagcaga aaaagaaaaa gaggagtctt 450

 tgggatacca ttaaaaagaa gaaaatttca gcctctacaa gtcacaacag 500

 aagggtttca aatattcaga atgttaataa aacatttagt gtttcccaaa 550

 aagttgacag agttaggagc ccactacaag cttgtgaaaa cttggctatg 600

 aatgaaggcg gtcccccaac agaaaacaat tctttaatac ttgaagaaaa 650

 taaaataccc atatcaccta ttagccctgc tttcaatgaa tgccatggtg 700

 caacttgctt gccactctct gtacgtcgat ctactaccta ctcatctctt 750

 catgcatcag aaaataggga actattaaat gtacacagtg ccaacgtttc 800

 aaaagtttct tttaatgaga aagctgtaac tgaaacttcc tttaattctg 850

 taaatgttaa tggccaaaga ggagagaata gtaaacttag tcttaccccc 900

 aactgttctt caactttgaa cattacacaa agccaaatac attttctaag 950

 tccagattct tttgtaaata atagtcatgg agctaataat gaactagaat 1000

 tagtaacatg tctttcatca gatatgttta tgaaagataa ttcacagcct 1050

 gtgcatttgg aatcaacaat tgcacatgaa atttatcaga aaattttaag 1100

 tccagattct ttcataaaag ataattatgg actaaatcag gatctagaat 1150

 cagagtcagt taatcctatt ttatccccta atcaattttt aaaagataac 1200

 atggcatata tgtgtacatc tcagcaaaca tgtaaagtac cattatcaaa 1250

 tgaaaattct caagtcccac agtctcctga agattggaga aaaagtgaag 1300

 tttcgccacg tattcctgaa tgtcagggtt caaaatctcc caaagctatt 1350

 tttgaagaac tagtagaaat gaagtcaaat tactacagtt ttataaaaca 1400

 aaataatcct aaattttctg cagttcagga tatttctagt catagccaca 1450

 ataaacaacc taagagacgt ccaatacttt ctgccactgt tactaaaagg 1500

 aaggccacct gtaccagaga aaaccaaact gagattaata aaccaaaagc 1550

 aaaaagatgt ctcaacagtg cagtgggtga acatgaaaaa gtaataaata 1600

 atcaaaagga aaaagaagat tttcattctt atcttccaat tatagatcca 1650

 atattaagta aatctaagag ttataaaaac gaggtaacac cctcttcgac 1700

 aacagcttca gttgctcgga aaagaaagag cgatggaagc atggaagatg 1750

 caaatgtgag agttgcaatt acagaacata cagaagtgcg agaaatcaaa 1800

 agaatccatt tttctccctc agagcctaaa acatcagctg ttaagaaaac 1850

 aaaaaatgtg acaacaccca tctcaaaacg tattagcaac agagagaaat 1900

 taaacctgaa gaagaaaact gatttatcaa tattcagaac tccaatttct 1950

 aaaacaaaca aaaggacaaa acccattatc gctgtggcac agtccagttt 2000

 gaccttcata aaaccattaa aaacagatat tcccagacac ccgatgccat 2050

 ttgctgcaaa aaacatgttt tatgatgaac gctggaagga aaagcaggaa 2100

 cagggcttca cttggtggtt aaattttata ttaacccctg atgacttcac 2150

 tgtaaaaaca aatatttctg aagtaaatgc tgctactctt cttttgggaa 2200

 tagagaatca acataaaata agtgttccta gagcacctac aaaagaggaa 2250

 atgtctctca gagcttatac tgctcggtgt aggttaaaca gactacgtcg 2300

 tgcagcatgc cgtttgttta cttctgaaaa aatggttaaa gctattaaaa 2350

 agcttgaaat tgaaattgaa gctaggcggt taattgttcg aaaagataga 2400

 cacctatgga aagatgtggg agaacgtcag aaagtcctga attggctgtt 2450

 gtcctacaat cctttgtggc ttcgaattgg tctagagaca acttatggag 2500

 aactcatatc tttggaagat aacagtgatg tcacagggtt ggctatgttt 2550

 attctgaatc gcctactttg gaatcctgat atagcagctg agtatagaca 2600

 ccccactgtt cctcacctgt atagagatgg tcatgaagaa gctttgtcca 2650

 agtttacatt gaaaaagtta ttgttgttgg tctgttttct tgattatgct 2700

 aaaatttcca gactcattga tcatgatcct tgtctcttct gtaaagatgc 2750

 cgaattcaag gctagtaaag aaatcctttt ggctttttca cgagatttcc 2800

 taagtggtga aggtgacctt tcccgtcacc ttggcttatt gggattacct 2850

 gttaaccatg ttcagacacc atttgatgaa tttgattttg ccgttacaaa 2900

 tcttgccgta gacttgcaat gtggagtgcg ccttgtgcga accatggaac 2950

 ttctcacaca gaactgggac ctctcaaaga aactcaggat tccggcaata 3000

 agtcgtcttc aaaagatgca caatgttgac attgttcttc aagttcttaa 3050

 atcacgagga attgaattaa gtgatgagca tggaaataca attctatcta 3100

 aggatattgt ggataggcac agagaaaaaa ctctcaggtt gctttggaaa 3150

 atagcgtttg cttttcaggt ggatatttcc cttaacttag atcaattaaa 3200

 ggaagaaatt gcctttctaa aacacacaaa gagtataaag aaaacaatat 3250

 ctctactatc atgccattct gatgatctta ttaataagaa aaaaggcaaa 3300

 agggatagtg gttcctttga acaatatagt gaaaacataa agttattgat 3350

 ggattgggta aatgctgttt gtgccttcta taataaaaag gtggagaatt 3400

 ttacagtgtc tttctcagac ggccgtgtgt tatgttacct gatccaccat 3450

 taccatcctt gctatgtgcc atttgacgct atatgtcagc gtactactca 3500

 aactgtggaa tgtacgcaaa ctggttcagt ggtattaaat tcatcatctg 3550

 aatctgatga cagttctctg gatatgtcac ttaaagcatt tgatcatgaa 3600

 aatacttcag agctatacaa agagctccta gaaaatgaaa agaaaaattt 3650

 tcacttggtt aggtctgcag ttagagacct tggtggaata cctgctatga 3700

 ttaatcattc agatatgtca aatacaattc cagatgaaaa ggtggttatt 3750

 acctatttgt catttctttg tgcaaggctt ttggatcttc gtaaagaaat 3800

 aagagctgct cgactcatac aaacaacatg gagaaaatat aaactaaaaa 3850

 cagatctcaa acgccatcag gagagagaga aagctgcaag aattattcaa 3900

 ttggctgtaa tcaattttct agcaaaacaa agattgagaa aaagagttaa 3950

 tgcagcactc gtcattcaga aatattggcg aagagtctta gcacagagaa 4000

 aattattaat gttaaaaaag gaaaagctgg aaaaagttca aaataaagca 4050

 gcatcactta ttcagggata ttggagaaga tattccacta gacaaagatt 4100

 tctgaaattg aaatattatt caatcatcct gcaatctagg ataagaatga 4150

 taattgctgt tacatcttat aaacgatatc tttgggctac agttacaatt 4200

 cagaggcatt ggcgtgctta tttaagaaga aaacaagatc aacaaagata 4250

 tgaaatgcta aaatcatcaa ctcttataat ccaatctatg ttcagaaaat 4300

 ggaagcaacg taaaatgcaa tcacaagtaa aagctacagt aatattgcaa 4350

 agagctttta gagaatggca tttaagaaaa caagctaaag aagaaaattc 4400

 tgctattatc atacaatcat ggtatagaat gcataaagaa ttacggaagt 4450

 atatttatat tagatcttgt gttgttatca ttcagaaaag atttcggtgc 4500

 tttcaagccc aaaagttata taaaagaaga aaagagtcca tactaaccat 4550

 ccagaagtac tacaaagcat atctgaaagg aaagattgag cgcaccaact 4600

 atttgcagaa acgagctgca gccattcaat tacaagctgc ttttaggaga 4650

 ctgaaagctc ataatttatg tagacaaatt agagctgctt gtgttattca 4700

 gtcatactgg agaatgagac aagacagagt tcgattttta aaccttaaga 4750

 agactattat caaatttcag gcacatgtaa gaaaacatca acaacgacag 4800

 aaatataaga agatgaagaa agcagctgtt ataattcaga ctcatttccg 4850

 agcttatatt tttgccatga aagttctagc atcttaccag aaaacacgct 4900

 ctgctgtcat tgtgctgcag tctgcatata gagggatgca agccaggaaa 4950

 atgtatattc acatcctcac atctgttata aagattcaat catattatcg 5000

 tgcttatgtt tctaaaaagg aatttttgag cctaaaaaat gctacaataa 5050

 aattgcagtc aactgttaag atgaaacaaa cacgtaaaca atatttgcat 5100

 ttaagagcag ctgcactatt tatccagcaa tgttaccgtt ccaaaaaaat 5150

 agctgcacaa aagagagaag agtatatgca gatgcgggaa tcttgtatca 5200

 aactgcaagc atttgttaga ggataccttg tccgaaagca gatgaggtta 5250

 caaagaaaag ctgttatttc actacagtct tatttcagaa tgagaaaggc 5300

 tcggcagtat tatctgaaaa tgtataaagc aattattgtc attcagaatt 5350

 actatcatgc atacaaagca caggtcaatc agaggaagaa cttcttgcaa 5400

 gtcaaaaaag cagctacttg cttgcaagca gcttacagag gttataaagt 5450

 acgccagcta atcaaacaac aatctatagc tgctcttaaa attcagtctg 5500

 cttttagagg ctataataaa agggtaaaat atcaatctgt gcttcaatct 5550

 ataataaaga ttcagagatg gtacagggcg tacaagactc ttcatgatac 5600

 aagaacacat tttttgaaga caaaggcagc tgtgatttcc ctccagtctg 5650

 cttatcgtgg ctggaaggtt cggaaacaga ttagaaggga acatcaagct 5700

 gccttgaaga ttcagtctgc ttttagaatg gccaaggccc agaaacagtt 5750

 tagattgttt aaaacagcag cattagtcat ccagcaaaat ttcagagcat 5800

 ggactgcagg aaggaagcaa tgtatggagt atattgaact ccgtcatgcg 5850

 gtactggtgc ttcaatctat gtggaaggga aaaacactga gaagacagct 5900

 tcaaaggcaa cataaatgtg ctatcatcat acagtcatac tatagaatgc 5950

 atgtgcaaca aaagaagtgg aaaatcatga aaaaagctgc tcttctgatt 6000

 caaaagtatt atagggctta cagtattgga agagaacaga atcatttata 6050

 tttgaaaaca aaagcagctg tagtaacttt acagtcagct tatcgtggta 6100

 tgaaagtgag aaaaagaata aaggattgca acaaagcagc agtcactata 6150

 cagtctaaat acagagctta caaaaccaaa aagaaatatg caacctatag 6200

 agcttcagct attataattc agagatggta tcgaggtatt aaaattacaa 6250

 accatcagca taaggagtat cttaatttga agaagacagc aattaaaatc 6300

 caatctgttt atagaggtat tagagttaga agacatattc aacacatgca 6350

 cagggcagcc acttttatta aagccatgtt taaaatgcat cagtcaagaa 6400

 taagttacca tacaatgaga aaagcagcta ttgttattca agtaagatgt 6450

 agagcatatt atcaaggtaa aatgcagcgt gaaaagtacc tgacaatttt 6500

 gaaagctgtt aaagtccttc aggcaagttt tagaggagta agagttagac 6550

 ggactcttag aaagatgcag actgcagcaa cactcattca gtcaaactac 6600

 agaagataca gacagcaaac atactttaat aagttaaaga aaataacaaa 6650

 aacagtacag caaagatact gggcaatgaa agaaagaaac atacaatttc 6700

 aaaggtataa caaactgagg cattctgtaa tatacattca ggctattttt 6750

 aggggaaaga aagctagaag acatttaaaa atgatgcata tagccgcaac 6800

 tctcattcag aggagattta gaactctaat gatgagaaga agattcctct 6850

 ctctcaagaa aactgctatt ttgattcaga gaaaatatcg ggcacatctt 6900

 tgtacaaagc atcacttaca gttccttcag gtacaaaatg cagttattaa 6950

 aatccagtca tcatacagaa gatggatgat aaggaaaagg atgcgagaga 7000

 tgcacagggc tgctactttc atccagtcta ctttcagaat gcacagatta 7050

 catatgagat atcgagcttt gaaacaggcc tccgttgtga tccaacagca 7100

 ataccaagca aatagagctg caaaactgca gaggcagcat tatctcagac 7150

 aaagacactc tgctgtgatc cttcaggctg cattcagggg tatgaaaact 7200

 agaagacatt tgaagagtat gcattcctct gcaaccctta ttcagagtag 7250

 gtttagatca ttactggtga ggagaagatt catttccctc aaaaaagcta 7300

 ctatttttgt tcagaggaaa tatcgagcca ccatttgtgc caaacataaa 7350

 ttgtaccaat tcttgcactt aagaaaggca gccattacaa tacagtcatc 7400

 ttacagaaga ctgatggtaa agaagaagtt acaagaaatg caaagggctg 7450

 cagttctcat tcaggctact ttcaggatgc acagaacata tattacattt 7500

 cagacttgga aacatgcttc aattctaatt cagcaacatt atcgaacata 7550

 tagagctgca aaattgcaaa gagaaaatta tatcagacaa tggcattctg 7600

 ctgtggttat tcaggctgca tataaaggaa tgaaagcaag acaactttta 7650

 agggaaaaac acaaagcttc tatcgtaata caaagcacct acagaatgta 7700

 taggcagtat tgtttctacc aaaagcttca gtgggctaca aaaatcatac 7750

 aagaaaaata tagagcaaat aaaaagaaac agaaagtatt tcaacacaat 7800

 gaacttaaga aagagacttg tgttcaggca ggttttcagg acatgaacat 7850

 aaaaaaacag attcaggaac agcaccaggc tgccattatt attcagaagc 7900

 attgtaaagc ctttaaaata aggaagcatt atctccacct tagagcaaca 7950

 gtagtttcta ttcaaagaag atacagaaaa ctaactgcag tgcgtaccca 8000

 agcagttatt tgtatacagt cttattacag aggctttaaa gtacgaaagg 8050

 atattcaaaa tatgcaccgg gctgccacac taattcagtc attctatcga 8100

 atgcacaggg ccaaagttga ttatgaaaca aagaaaactg caattgtggt 8150

 tatacagaat tattataggt tgtatgttag agtaaaaaca gaaagaaaaa 8200

 actttttagc agttcagaaa tctgtacgaa ctattcaggc tgcttttaga 8250

 ggcatgaaag ttagacaaaa attgaaaaat gtatcagagg aaaagatggc 8300

 agccattgtt aaccaatctg cactctgctg ttacagaagt aaaactcagt 8350

 atgaagctgt tcaaagtgaa ggtgttatga ttcaagagtg gtataaagct 8400

 tctggccttg cttgttcaca ggaagcagag tatcattctc aaagtagggc 8450

 tgcagtaaca attcaaaaag ctttttgtag aatggtcaca agaaaactgg 8500

 aaacacagaa atgtgctgcc ctacggattc agttcttcct tcagatggct 8550

 gtgtatcgga gaagatttgt tcagcagaaa agagctgcta tcactttaca 8600

 gcattatttt aggacgtggc aaaccagaaa acagttttta ctatatagaa 8650

 aagcagcagt ggttttacaa aatcactaca gagcatttct gtctgcaaaa 8700

 catcaaagac aagtctattt acagatcaga agcagtgtta tcattattca 8750

 agctagaagt aaaggattta tacagaaacg gaagtttcag gaaattaaaa 8800

 atagcaccat aaaaattcag gctatgtgga ggagatatag agccaagaaa 8850

 tatttatgta aagtgaaagc tgcctgcaag attcaagcct ggtatagatg 8900

 ttggagagca cacaaagaat atctagctat attaaaagct gttaaaatta 8950

 ttcaaggttg cttctatacc aaactagaga gaacacggtt tttgaatgtg 9000

 agagcatcag caattatcat tcagagaaaa tggagagcta tacttcctgc 9050

 aaagatagct catgaacact tcttaatgat aaaaagacat cgagctgctt 9100

 gtttgatcca agcacattat agaggatata aaggaaggca ggtctttctt 9150

 cggcagaaat ctgctgcttt gatcatacaa aaatatatac gagccaggga 9200

 ggctggaaag catgaaagga taaaatatat tgaatttaaa aaatctacag 9250

 ttatcctaca agcactggtg cgtggttggc tagtacgaaa aagattttta 9300

 gaacagagag ccaaaattcg acttcttcac ttcactgcag ctgcatatta 9350

 tcacctgaat gctgttagaa ttcaaagagc ctataaactt tacctggctg 9400

 tgaagaatgc taacaagcag gttaattcag tcatctgtat tcagagatgg 9450

 tttcgagcaa gattacaaga aaagagattt attcagaaat atcatagcat 9500

 caaaaagatt gagcatgaag gtcaagaatg tctgagccag cgaaataggg 9550

 ctgcatcagt aatacagaaa gcagtgcgcc attttctcct ccgtaaaaag 9600

 caggaaaaat tcactagtgg aatcattaaa attcaggcat tatggagagg 9650

 ctattcttgg aggaagaaaa atgattgtac aaaaattaaa gctatacgac 9700

 taagtcttca agttgttaat agggagattc gagaagaaaa caaactctac 9750

 aaaagaactg cacttgcact tcattacctt ttgacatata agcacctttc 9800

 tgccattctt gaggccttaa aacacctaga ggtagttact agattgtctc 9850

 cactttgttg tgagaacatg gcccagagtg gagcaatttc taaaatattt 9900

 gttttgatcc gaagttgtaa tcgcagtatt ccttgtatgg aagtcatcag 9950

 atatgctgtg caagtcttgc ttaatgtatc taagtatgag aaaactactt 10000

 cagcagttta tgatgtagaa aattgtatag atatactatt ggagcttttg 10050

 cagatatacc gagaaaagcc tggtaataaa gttgcagaca aaggcggaag 10100

 catttttaca aaaacttgtt gtttgttggc tattttactg aagacaacaa 10150

 atagagcctc tgatgtacga agtaggtcca aagttgttga ccgtatttac 10200

 agtctctaca aacttacagc tcataaacat aaaatgaata ctgaaagaat 10250

 actttacaag caaaagaaga attcttctat aagcattcct tttatcccag 10300

 aaacacctgt aaggaccaga atagtttcaa gacttaagcc agattgggtt 10350

 ttgagaagag ataacatgga agaaatcaca aatcccctgc aagctattca 10400

 aatggtgatg gatacgcttg gcattcctta ttag 10434

<210> 5092
<211> 3477
<212> PRT
<213> Homo sapien

<400> 5092
 Met Ala Asn Arg Arg Val Gly Arg Gly Cys Trp Glu Val Ser Pro
   1               5                  10                  15

 Thr Glu Arg Arg Pro Pro Ala Gly Leu Arg Gly Pro Ala Ala Glu
                  20                  25                  30

 Glu Glu Ala Ser Ser Pro Pro Val Leu Ser Leu Ser His Phe Cys
                  35                  40                  45

 Arg Ser Pro Phe Leu Cys Phe Gly Asp Val Leu Leu Gly Ala Ser
                  50                  55                  60

 Arg Thr Leu Ser Leu Ala Leu Asp Asn Pro Asn Glu Glu Val Ala
                  65                  70                  75

 Glu Val Lys Ile Ser His Phe Pro Ala Ala Asp Leu Gly Phe Ser
                  80                  85                  90

 Val Ser Gln Arg Cys Phe Val Leu Gln Pro Lys Glu Lys Ile Val
                  95                 100                 105

 Ile Ser Val Asn Trp Thr Pro Leu Lys Glu Gly Arg Val Arg Glu
                 110                 115                 120

 Ile Met Thr Phe Leu Val Asn Asp Val Leu Lys His Gln Ala Ile
                 125                 130                 135

 Leu Leu Gly Asn Ala Glu Glu Gln Lys Lys Lys Lys Arg Ser Leu
                 140                 145                 150

 Trp Asp Thr Ile Lys Lys Lys Lys Ile Ser Ala Ser Thr Ser His
                 155                 160                 165

 Asn Arg Arg Val Ser Asn Ile Gln Asn Val Asn Lys Thr Phe Ser
                 170                 175                 180

 Val Ser Gln Lys Val Asp Arg Val Arg Ser Pro Leu Gln Ala Cys
                 185                 190                 195

 Glu Asn Leu Ala Met Asn Glu Gly Gly Pro Pro Thr Glu Asn Asn
                 200                 205                 210

 Ser Leu Ile Leu Glu Glu Asn Lys Ile Pro Ile Ser Pro Ile Ser
                 215                 220                 225

 Pro Ala Phe Asn Glu Cys His Gly Ala Thr Cys Leu Pro Leu Ser
                 230                 235                 240

 Val Arg Arg Ser Thr Thr Tyr Ser Ser Leu His Ala Ser Glu Asn
                 245                 250                 255

 Arg Glu Leu Leu Asn Val His Ser Ala Asn Val Ser Lys Val Ser
                 260                 265                 270

 Phe Asn Glu Lys Ala Val Thr Glu Thr Ser Phe Asn Ser Val Asn
                 275                 280                 285

 Val Asn Gly Gln Arg Gly Glu Asn Ser Lys Leu Ser Leu Thr Pro
                 290                 295                 300

 Asn Cys Ser Ser Thr Leu Asn Ile Thr Gln Ser Gln Ile His Phe
                 305                 310                 315

 Leu Ser Pro Asp Ser Phe Val Asn Asn Ser His Gly Ala Asn Asn
                 320                 325                 330

 Glu Leu Glu Leu Val Thr Cys Leu Ser Ser Asp Met Phe Met Lys
                 335                 340                 345

 Asp Asn Ser Gln Pro Val His Leu Glu Ser Thr Ile Ala His Glu
                 350                 355                 360

 Ile Tyr Gln Lys Ile Leu Ser Pro Asp Ser Phe Ile Lys Asp Asn
                 365                 370                 375

 Tyr Gly Leu Asn Gln Asp Leu Glu Ser Glu Ser Val Asn Pro Ile
                 380                 385                 390

 Leu Ser Pro Asn Gln Phe Leu Lys Asp Asn Met Ala Tyr Met Cys
                 395                 400                 405

 Thr Ser Gln Gln Thr Cys Lys Val Pro Leu Ser Asn Glu Asn Ser
                 410                 415                 420

 Gln Val Pro Gln Ser Pro Glu Asp Trp Arg Lys Ser Glu Val Ser
                 425                 430                 435

 Pro Arg Ile Pro Glu Cys Gln Gly Ser Lys Ser Pro Lys Ala Ile
                 440                 445                 450

 Phe Glu Glu Leu Val Glu Met Lys Ser Asn Tyr Tyr Ser Phe Ile
                 455                 460                 465

 Lys Gln Asn Asn Pro Lys Phe Ser Ala Val Gln Asp Ile Ser Ser
                 470                 475                 480

 His Ser His Asn Lys Gln Pro Lys Arg Arg Pro Ile Leu Ser Ala
                 485                 490                 495

 Thr Val Thr Lys Arg Lys Ala Thr Cys Thr Arg Glu Asn Gln Thr
                 500                 505                 510

 Glu Ile Asn Lys Pro Lys Ala Lys Arg Cys Leu Asn Ser Ala Val
                 515                 520                 525

 Gly Glu His Glu Lys Val Ile Asn Asn Gln Lys Glu Lys Glu Asp
                 530                 535                 540

 Phe His Ser Tyr Leu Pro Ile Ile Asp Pro Ile Leu Ser Lys Ser
                 545                 550                 555

 Lys Ser Tyr Lys Asn Glu Val Thr Pro Ser Ser Thr Thr Ala Ser
                 560                 565                 570

 Val Ala Arg Lys Arg Lys Ser Asp Gly Ser Met Glu Asp Ala Asn
                 575                 580                 585

 Val Arg Val Ala Ile Thr Glu His Thr Glu Val Arg Glu Ile Lys
                 590                 595                 600

 Arg Ile His Phe Ser Pro Ser Glu Pro Lys Thr Ser Ala Val Lys
                 605                 610                 615

 Lys Thr Lys Asn Val Thr Thr Pro Ile Ser Lys Arg Ile Ser Asn
                 620                 625                 630

 Arg Glu Lys Leu Asn Leu Lys Lys Lys Thr Asp Leu Ser Ile Phe
                 635                 640                 645

 Arg Thr Pro Ile Ser Lys Thr Asn Lys Arg Thr Lys Pro Ile Ile
                 650                 655                 660

 Ala Val Ala Gln Ser Ser Leu Thr Phe Ile Lys Pro Leu Lys Thr
                 665                 670                 675

 Asp Ile Pro Arg His Pro Met Pro Phe Ala Ala Lys Asn Met Phe
                 680                 685                 690

 Tyr Asp Glu Arg Trp Lys Glu Lys Gln Glu Gln Gly Phe Thr Trp
                 695                 700                 705

 Trp Leu Asn Phe Ile Leu Thr Pro Asp Asp Phe Thr Val Lys Thr
                 710                 715                 720

 Asn Ile Ser Glu Val Asn Ala Ala Thr Leu Leu Leu Gly Ile Glu
                 725                 730                 735

 Asn Gln His Lys Ile Ser Val Pro Arg Ala Pro Thr Lys Glu Glu
                 740                 745                 750

 Met Ser Leu Arg Ala Tyr Thr Ala Arg Cys Arg Leu Asn Arg Leu
                 755                 760                 765

 Arg Arg Ala Ala Cys Arg Leu Phe Thr Ser Glu Lys Met Val Lys
                 770                 775                 780

 Ala Ile Lys Lys Leu Glu Ile Glu Ile Glu Ala Arg Arg Leu Ile
                 785                 790                 795

 Val Arg Lys Asp Arg His Leu Trp Lys Asp Val Gly Glu Arg Gln
                 800                 805                 810

 Lys Val Leu Asn Trp Leu Leu Ser Tyr Asn Pro Leu Trp Leu Arg
                 815                 820                 825

 Ile Gly Leu Glu Thr Thr Tyr Gly Glu Leu Ile Ser Leu Glu Asp
                 830                 835                 840

 Asn Ser Asp Val Thr Gly Leu Ala Met Phe Ile Leu Asn Arg Leu
                 845                 850                 855

 Leu Trp Asn Pro Asp Ile Ala Ala Glu Tyr Arg His Pro Thr Val
                 860                 865                 870

 Pro His Leu Tyr Arg Asp Gly His Glu Glu Ala Leu Ser Lys Phe
                 875                 880                 885

 Thr Leu Lys Lys Leu Leu Leu Leu Val Cys Phe Leu Asp Tyr Ala
                 890                 895                 900

 Lys Ile Ser Arg Leu Ile Asp His Asp Pro Cys Leu Phe Cys Lys
                 905                 910                 915

 Asp Ala Glu Phe Lys Ala Ser Lys Glu Ile Leu Leu Ala Phe Ser
                 920                 925                 930

 Arg Asp Phe Leu Ser Gly Glu Gly Asp Leu Ser Arg His Leu Gly
                 935                 940                 945

 Leu Leu Gly Leu Pro Val Asn His Val Gln Thr Pro Phe Asp Glu
                 950                 955                 960

 Phe Asp Phe Ala Val Thr Asn Leu Ala Val Asp Leu Gln Cys Gly
                 965                 970                 975

 Val Arg Leu Val Arg Thr Met Glu Leu Leu Thr Gln Asn Trp Asp
                 980                 985                 990

 Leu Ser Lys Lys Leu Arg Ile Pro Ala Ile Ser Arg Leu Gln Lys
                 995                1000                1005

 Met His Asn Val Asp Ile Val Leu Gln Val Leu Lys Ser Arg Gly
                1010                1015                1020

 Ile Glu Leu Ser Asp Glu His Gly Asn Thr Ile Leu Ser Lys Asp
                1025                1030                1035

 Ile Val Asp Arg His Arg Glu Lys Thr Leu Arg Leu Leu Trp Lys
                1040                1045                1050

 Ile Ala Phe Ala Phe Gln Val Asp Ile Ser Leu Asn Leu Asp Gln
                1055                1060                1065

 Leu Lys Glu Glu Ile Ala Phe Leu Lys His Thr Lys Ser Ile Lys
                1070                1075                1080

 Lys Thr Ile Ser Leu Leu Ser Cys His Ser Asp Asp Leu Ile Asn
                1085                1090                1095

 Lys Lys Lys Gly Lys Arg Asp Ser Gly Ser Phe Glu Gln Tyr Ser
                1100                1105                1110

 Glu Asn Ile Lys Leu Leu Met Asp Trp Val Asn Ala Val Cys Ala
                1115                1120                1125

 Phe Tyr Asn Lys Lys Val Glu Asn Phe Thr Val Ser Phe Ser Asp
                1130                1135                1140

 Gly Arg Val Leu Cys Tyr Leu Ile His His Tyr His Pro Cys Tyr
                1145                1150                1155

 Val Pro Phe Asp Ala Ile Cys Gln Arg Thr Thr Gln Thr Val Glu
                1160                1165                1170

 Cys Thr Gln Thr Gly Ser Val Val Leu Asn Ser Ser Ser Glu Ser
                1175                1180                1185

 Asp Asp Ser Ser Leu Asp Met Ser Leu Lys Ala Phe Asp His Glu
                1190                1195                1200

 Asn Thr Ser Glu Leu Tyr Lys Glu Leu Leu Glu Asn Glu Lys Lys
                1205                1210                1215

 Asn Phe His Leu Val Arg Ser Ala Val Arg Asp Leu Gly Gly Ile
                1220                1225                1230

 Pro Ala Met Ile Asn His Ser Asp Met Ser Asn Thr Ile Pro Asp
                1235                1240                1245

 Glu Lys Val Val Ile Thr Tyr Leu Ser Phe Leu Cys Ala Arg Leu
                1250                1255                1260

 Leu Asp Leu Arg Lys Glu Ile Arg Ala Ala Arg Leu Ile Gln Thr
                1265                1270                1275

 Thr Trp Arg Lys Tyr Lys Leu Lys Thr Asp Leu Lys Arg His Gln
                1280                1285                1290

 Glu Arg Glu Lys Ala Ala Arg Ile Ile Gln Leu Ala Val Ile Asn
                1295                1300                1305

 Phe Leu Ala Lys Gln Arg Leu Arg Lys Arg Val Asn Ala Ala Leu
                1310                1315                1320

 Val Ile Gln Lys Tyr Trp Arg Arg Val Leu Ala Gln Arg Lys Leu
                1325                1330                1335

 Leu Met Leu Lys Lys Glu Lys Leu Glu Lys Val Gln Asn Lys Ala
                1340                1345                1350

 Ala Ser Leu Ile Gln Gly Tyr Trp Arg Arg Tyr Ser Thr Arg Gln
                1355                1360                1365

 Arg Phe Leu Lys Leu Lys Tyr Tyr Ser Ile Ile Leu Gln Ser Arg
                1370                1375                1380

 Ile Arg Met Ile Ile Ala Val Thr Ser Tyr Lys Arg Tyr Leu Trp
                1385                1390                1395

 Ala Thr Val Thr Ile Gln Arg His Trp Arg Ala Tyr Leu Arg Arg
                1400                1405                1410

 Lys Gln Asp Gln Gln Arg Tyr Glu Met Leu Lys Ser Ser Thr Leu
                1415                1420                1425

 Ile Ile Gln Ser Met Phe Arg Lys Trp Lys Gln Arg Lys Met Gln
                1430                1435                1440

 Ser Gln Val Lys Ala Thr Val Ile Leu Gln Arg Ala Phe Arg Glu
                1445                1450                1455

 Trp His Leu Arg Lys Gln Ala Lys Glu Glu Asn Ser Ala Ile Ile
                1460                1465                1470

 Ile Gln Ser Trp Tyr Arg Met His Lys Glu Leu Arg Lys Tyr Ile
                1475                1480                1485

 Tyr Ile Arg Ser Cys Val Val Ile Ile Gln Lys Arg Phe Arg Cys
                1490                1495                1500

 Phe Gln Ala Gln Lys Leu Tyr Lys Arg Arg Lys Glu Ser Ile Leu
                1505                1510                1515

 Thr Ile Gln Lys Tyr Tyr Lys Ala Tyr Leu Lys Gly Lys Ile Glu
                1520                1525                1530

 Arg Thr Asn Tyr Leu Gln Lys Arg Ala Ala Ala Ile Gln Leu Gln
                1535                1540                1545

 Ala Ala Phe Arg Arg Leu Lys Ala His Asn Leu Cys Arg Gln Ile
                1550                1555                1560

 Arg Ala Ala Cys Val Ile Gln Ser Tyr Trp Arg Met Arg Gln Asp
                1565                1570                1575

 Arg Val Arg Phe Leu Asn Leu Lys Lys Thr Ile Ile Lys Phe Gln
                1580                1585                1590

 Ala His Val Arg Lys His Gln Gln Arg Gln Lys Tyr Lys Lys Met
                1595                1600                1605

 Lys Lys Ala Ala Val Ile Ile Gln Thr His Phe Arg Ala Tyr Ile
                1610                1615                1620

 Phe Ala Met Lys Val Leu Ala Ser Tyr Gln Lys Thr Arg Ser Ala
                1625                1630                1635

 Val Ile Val Leu Gln Ser Ala Tyr Arg Gly Met Gln Ala Arg Lys
                1640                1645                1650

 Met Tyr Ile His Ile Leu Thr Ser Val Ile Lys Ile Gln Ser Tyr
                1655                1660                1665

 Tyr Arg Ala Tyr Val Ser Lys Lys Glu Phe Leu Ser Leu Lys Asn
                1670                1675                1680

 Ala Thr Ile Lys Leu Gln Ser Thr Val Lys Met Lys Gln Thr Arg
                1685                1690                1695

 Lys Gln Tyr Leu His Leu Arg Ala Ala Ala Leu Phe Ile Gln Gln
                1700                1705                1710

 Cys Tyr Arg Ser Lys Lys Ile Ala Ala Gln Lys Arg Glu Glu Tyr
                1715                1720                1725

 Met Gln Met Arg Glu Ser Cys Ile Lys Leu Gln Ala Phe Val Arg
                1730                1735                1740

 Gly Tyr Leu Val Arg Lys Gln Met Arg Leu Gln Arg Lys Ala Val
                1745                1750                1755

 Ile Ser Leu Gln Ser Tyr Phe Arg Met Arg Lys Ala Arg Gln Tyr
                1760                1765                1770

 Tyr Leu Lys Met Tyr Lys Ala Ile Ile Val Ile Gln Asn Tyr Tyr
                1775                1780                1785

 His Ala Tyr Lys Ala Gln Val Asn Gln Arg Lys Asn Phe Leu Gln
                1790                1795                1800

 Val Lys Lys Ala Ala Thr Cys Leu Gln Ala Ala Tyr Arg Gly Tyr
                1805                1810                1815

 Lys Val Arg Gln Leu Ile Lys Gln Gln Ser Ile Ala Ala Leu Lys
                1820                1825                1830

 Ile Gln Ser Ala Phe Arg Gly Tyr Asn Lys Arg Val Lys Tyr Gln
                1835                1840                1845

 Ser Val Leu Gln Ser Ile Ile Lys Ile Gln Arg Trp Tyr Arg Ala
                1850                1855                1860

 Tyr Lys Thr Leu His Asp Thr Arg Thr His Phe Leu Lys Thr Lys
                1865                1870                1875

 Ala Ala Val Ile Ser Leu Gln Ser Ala Tyr Arg Gly Trp Lys Val
                1880                1885                1890

 Arg Lys Gln Ile Arg Arg Glu His Gln Ala Ala Leu Lys Ile Gln
                1895                1900                1905

 Ser Ala Phe Arg Met Ala Lys Ala Gln Lys Gln Phe Arg Leu Phe
                1910                1915                1920

 Lys Thr Ala Ala Leu Val Ile Gln Gln Asn Phe Arg Ala Trp Thr
                1925                1930                1935

 Ala Gly Arg Lys Gln Cys Met Glu Tyr Ile Glu Leu Arg His Ala
                1940                1945                1950

 Val Leu Val Leu Gln Ser Met Trp Lys Gly Lys Thr Leu Arg Arg
                1955                1960                1965

 Gln Leu Gln Arg Gln His Lys Cys Ala Ile Ile Ile Gln Ser Tyr
                1970                1975                1980

 Tyr Arg Met His Val Gln Gln Lys Lys Trp Lys Ile Met Lys Lys
                1985                1990                1995

 Ala Ala Leu Leu Ile Gln Lys Tyr Tyr Arg Ala Tyr Ser Ile Gly
                2000                2005                2010

 Arg Glu Gln Asn His Leu Tyr Leu Lys Thr Lys Ala Ala Val Val
                2015                2020                2025

 Thr Leu Gln Ser Ala Tyr Arg Gly Met Lys Val Arg Lys Arg Ile
                2030                2035                2040

 Lys Asp Cys Asn Lys Ala Ala Val Thr Ile Gln Ser Lys Tyr Arg
                2045                2050                2055

 Ala Tyr Lys Thr Lys Lys Lys Tyr Ala Thr Tyr Arg Ala Ser Ala
                2060                2065                2070

 Ile Ile Ile Gln Arg Trp Tyr Arg Gly Ile Lys Ile Thr Asn His
                2075                2080                2085

 Gln His Lys Glu Tyr Leu Asn Leu Lys Lys Thr Ala Ile Lys Ile
                2090                2095                2100

 Gln Ser Val Tyr Arg Gly Ile Arg Val Arg Arg His Ile Gln His
                2105                2110                2115

 Met His Arg Ala Ala Thr Phe Ile Lys Ala Met Phe Lys Met His
                2120                2125                2130

 Gln Ser Arg Ile Ser Tyr His Thr Met Arg Lys Ala Ala Ile Val
                2135                2140                2145

 Ile Gln Val Arg Cys Arg Ala Tyr Tyr Gln Gly Lys Met Gln Arg
                2150                2155                2160

 Glu Lys Tyr Leu Thr Ile Leu Lys Ala Val Lys Val Leu Gln Ala
                2165                2170                2175

 Ser Phe Arg Gly Val Arg Val Arg Arg Thr Leu Arg Lys Met Gln
                2180                2185                2190

 Thr Ala Ala Thr Leu Ile Gln Ser Asn Tyr Arg Arg Tyr Arg Gln
                2195                2200                2205

 Gln Thr Tyr Phe Asn Lys Leu Lys Lys Ile Thr Lys Thr Val Gln
                2210                2215                2220

 Gln Arg Tyr Trp Ala Met Lys Glu Arg Asn Ile Gln Phe Gln Arg
                2225                2230                2235

 Tyr Asn Lys Leu Arg His Ser Val Ile Tyr Ile Gln Ala Ile Phe
                2240                2245                2250

 Arg Gly Lys Lys Ala Arg Arg His Leu Lys Met Met His Ile Ala
                2255                2260                2265

 Ala Thr Leu Ile Gln Arg Arg Phe Arg Thr Leu Met Met Arg Arg
                2270                2275                2280

 Arg Phe Leu Ser Leu Lys Lys Thr Ala Ile Leu Ile Gln Arg Lys
                2285                2290                2295

 Tyr Arg Ala His Leu Cys Thr Lys His His Leu Gln Phe Leu Gln
                2300                2305                2310

 Val Gln Asn Ala Val Ile Lys Ile Gln Ser Ser Tyr Arg Arg Trp
                2315                2320                2325

 Met Ile Arg Lys Arg Met Arg Glu Met His Arg Ala Ala Thr Phe
                2330                2335                2340

 Ile Gln Ser Thr Phe Arg Met His Arg Leu His Met Arg Tyr Arg
                2345                2350                2355

 Ala Leu Lys Gln Ala Ser Val Val Ile Gln Gln Gln Tyr Gln Ala
                2360                2365                2370

 Asn Arg Ala Ala Lys Leu Gln Arg Gln His Tyr Leu Arg Gln Arg
                2375                2380                2385

 His Ser Ala Val Ile Leu Gln Ala Ala Phe Arg Gly Met Lys Thr
                2390                2395                2400

 Arg Arg His Leu Lys Ser Met His Ser Ser Ala Thr Leu Ile Gln
                2405                2410                2415

 Ser Arg Phe Arg Ser Leu Leu Val Arg Arg Arg Phe Ile Ser Leu
                2420                2425                2430

 Lys Lys Ala Thr Ile Phe Val Gln Arg Lys Tyr Arg Ala Thr Ile
                2435                2440                2445

 Cys Ala Lys His Lys Leu Tyr Gln Phe Leu His Leu Arg Lys Ala
                2450                2455                2460

 Ala Ile Thr Ile Gln Ser Ser Tyr Arg Arg Leu Met Val Lys Lys
                2465                2470                2475

 Lys Leu Gln Glu Met Gln Arg Ala Ala Val Leu Ile Gln Ala Thr
                2480                2485                2490

 Phe Arg Met His Arg Thr Tyr Ile Thr Phe Gln Thr Trp Lys His
                2495                2500                2505

 Ala Ser Ile Leu Ile Gln Gln His Tyr Arg Thr Tyr Arg Ala Ala
                2510                2515                2520

 Lys Leu Gln Arg Glu Asn Tyr Ile Arg Gln Trp His Ser Ala Val
                2525                2530                2535

 Val Ile Gln Ala Ala Tyr Lys Gly Met Lys Ala Arg Gln Leu Leu
                2540                2545                2550

 Arg Glu Lys His Lys Ala Ser Ile Val Ile Gln Ser Thr Tyr Arg
                2555                2560                2565

 Met Tyr Arg Gln Tyr Cys Phe Tyr Gln Lys Leu Gln Trp Ala Thr
                2570                2575                2580

 Lys Ile Ile Gln Glu Lys Tyr Arg Ala Asn Lys Lys Lys Gln Lys
                2585                2590                2595

 Val Phe Gln His Asn Glu Leu Lys Lys Glu Thr Cys Val Gln Ala
                2600                2605                2610

 Gly Phe Gln Asp Met Asn Ile Lys Lys Gln Ile Gln Glu Gln His
                2615                2620                2625

 Gln Ala Ala Ile Ile Ile Gln Lys His Cys Lys Ala Phe Lys Ile
                2630                2635                2640

 Arg Lys His Tyr Leu His Leu Arg Ala Thr Val Val Ser Ile Gln
                2645                2650                2655

 Arg Arg Tyr Arg Lys Leu Thr Ala Val Arg Thr Gln Ala Val Ile
                2660                2665                2670

 Cys Ile Gln Ser Tyr Tyr Arg Gly Phe Lys Val Arg Lys Asp Ile
                2675                2680                2685

 Gln Asn Met His Arg Ala Ala Thr Leu Ile Gln Ser Phe Tyr Arg
                2690                2695                2700

 Met His Arg Ala Lys Val Asp Tyr Glu Thr Lys Lys Thr Ala Ile
                2705                2710                2715

 Val Val Ile Gln Asn Tyr Tyr Arg Leu Tyr Val Arg Val Lys Thr
                2720                2725                2730

 Glu Arg Lys Asn Phe Leu Ala Val Gln Lys Ser Val Arg Thr Ile
                2735                2740                2745

 Gln Ala Ala Phe Arg Gly Met Lys Val Arg Gln Lys Leu Lys Asn
                2750                2755                2760

 Val Ser Glu Glu Lys Met Ala Ala Ile Val Asn Gln Ser Ala Leu
                2765                2770                2775

 Cys Cys Tyr Arg Ser Lys Thr Gln Tyr Glu Ala Val Gln Ser Glu
                2780                2785                2790

 Gly Val Met Ile Gln Glu Trp Tyr Lys Ala Ser Gly Leu Ala Cys
                2795                2800                2805

 Ser Gln Glu Ala Glu Tyr His Ser Gln Ser Arg Ala Ala Val Thr
                2810                2815                2820

 Ile Gln Lys Ala Phe Cys Arg Met Val Thr Arg Lys Leu Glu Thr
                2825                2830                2835

 Gln Lys Cys Ala Ala Leu Arg Ile Gln Phe Phe Leu Gln Met Ala
                2840                2845                2850

 Val Tyr Arg Arg Arg Phe Val Gln Gln Lys Arg Ala Ala Ile Thr
                2855                2860                2865

 Leu Gln His Tyr Phe Arg Thr Trp Gln Thr Arg Lys Gln Phe Leu
                2870                2875                2880

 Leu Tyr Arg Lys Ala Ala Val Val Leu Gln Asn His Tyr Arg Ala
                2885                2890                2895

 Phe Leu Ser Ala Lys His Gln Arg Gln Val Tyr Leu Gln Ile Arg
                2900                2905                2910

 Ser Ser Val Ile Ile Ile Gln Ala Arg Ser Lys Gly Phe Ile Gln
                2915                2920                2925

 Lys Arg Lys Phe Gln Glu Ile Lys Asn Ser Thr Ile Lys Ile Gln
                2930                2935                2940

 Ala Met Trp Arg Arg Tyr Arg Ala Lys Lys Tyr Leu Cys Lys Val
                2945                2950                2955

 Lys Ala Ala Cys Lys Ile Gln Ala Trp Tyr Arg Cys Trp Arg Ala
                2960                2965                2970

 His Lys Glu Tyr Leu Ala Ile Leu Lys Ala Val Lys Ile Ile Gln
                2975                2980                2985

 Gly Cys Phe Tyr Thr Lys Leu Glu Arg Thr Arg Phe Leu Asn Val
                2990                2995                3000

 Arg Ala Ser Ala Ile Ile Ile Gln Arg Lys Trp Arg Ala Ile Leu
                3005                3010                3015

 Pro Ala Lys Ile Ala His Glu His Phe Leu Met Ile Lys Arg His
                3020                3025                3030

 Arg Ala Ala Cys Leu Ile Gln Ala His Tyr Arg Gly Tyr Lys Gly
                3035                3040                3045

 Arg Gln Val Phe Leu Arg Gln Lys Ser Ala Ala Leu Ile Ile Gln
                3050                3055                3060

 Lys Tyr Ile Arg Ala Arg Glu Ala Gly Lys His Glu Arg Ile Lys
                3065                3070                3075

 Tyr Ile Glu Phe Lys Lys Ser Thr Val Ile Leu Gln Ala Leu Val
                3080                3085                3090

 Arg Gly Trp Leu Val Arg Lys Arg Phe Leu Glu Gln Arg Ala Lys
                3095                3100                3105

 Ile Arg Leu Leu His Phe Thr Ala Ala Ala Tyr Tyr His Leu Asn
                3110                3115                3120

 Ala Val Arg Ile Gln Arg Ala Tyr Lys Leu Tyr Leu Ala Val Lys
                3125                3130                3135

 Asn Ala Asn Lys Gln Val Asn Ser Val Ile Cys Ile Gln Arg Trp
                3140                3145                3150

 Phe Arg Ala Arg Leu Gln Glu Lys Arg Phe Ile Gln Lys Tyr His
                3155                3160                3165

 Ser Ile Lys Lys Ile Glu His Glu Gly Gln Glu Cys Leu Ser Gln
                3170                3175                3180

 Arg Asn Arg Ala Ala Ser Val Ile Gln Lys Ala Val Arg His Phe
                3185                3190                3195

 Leu Leu Arg Lys Lys Gln Glu Lys Phe Thr Ser Gly Ile Ile Lys
                3200                3205                3210

 Ile Gln Ala Leu Trp Arg Gly Tyr Ser Trp Arg Lys Lys Asn Asp
                3215                3220                3225

 Cys Thr Lys Ile Lys Ala Ile Arg Leu Ser Leu Gln Val Val Asn
                3230                3235                3240

 Arg Glu Ile Arg Glu Glu Asn Lys Leu Tyr Lys Arg Thr Ala Leu
                3245                3250                3255

 Ala Leu His Tyr Leu Leu Thr Tyr Lys His Leu Ser Ala Ile Leu
                3260                3265                3270

 Glu Ala Leu Lys His Leu Glu Val Val Thr Arg Leu Ser Pro Leu
                3275                3280                3285

 Cys Cys Glu Asn Met Ala Gln Ser Gly Ala Ile Ser Lys Ile Phe
                3290                3295                3300

 Val Leu Ile Arg Ser Cys Asn Arg Ser Ile Pro Cys Met Glu Val
                3305                3310                3315

 Ile Arg Tyr Ala Val Gln Val Leu Leu Asn Val Ser Lys Tyr Glu
                3320                3325                3330

 Lys Thr Thr Ser Ala Val Tyr Asp Val Glu Asn Cys Ile Asp Ile
                3335                3340                3345

 Leu Leu Glu Leu Leu Gln Ile Tyr Arg Glu Lys Pro Gly Asn Lys
                3350                3355                3360

 Val Ala Asp Lys Gly Gly Ser Ile Phe Thr Lys Thr Cys Cys Leu
                3365                3370                3375

 Leu Ala Ile Leu Leu Lys Thr Thr Asn Arg Ala Ser Asp Val Arg
                3380                3385                3390

 Ser Arg Ser Lys Val Val Asp Arg Ile Tyr Ser Leu Tyr Lys Leu
                3395                3400                3405

 Thr Ala His Lys His Lys Met Asn Thr Glu Arg Ile Leu Tyr Lys
                3410                3415                3420

 Gln Lys Lys Asn Ser Ser Ile Ser Ile Pro Phe Ile Pro Glu Thr
                3425                3430                3435

 Pro Val Arg Thr Arg Ile Val Ser Arg Leu Lys Pro Asp Trp Val
                3440                3445                3450

 Leu Arg Arg Asp Asn Met Glu Glu Ile Thr Asn Pro Leu Gln Ala
                3455                3460                3465

 Ile Gln Met Val Met Asp Thr Leu Gly Ile Pro Tyr
                3470                3475

<210> 5093
<211> 4474
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3707-3726, 4456
<223> Unknown base

<400> 5093
 ttatgttaaa ataaaggtca tcaaaagata ttttcctaaa cctttccttt 50

 accagaaata tctctagtgt cacatggtcc tttctccctt cttgcttttg 100

 taggaatcca aagctaatct gtccctgatc cggattgcac gcacctgtgc 150

 cttttggggc ccttctgcat tagttcttcc ttctcttcta acctcaaaaa 200

 tgtgttttct ctattggctc tttcccttta acatagaagt atactcacgc 250

 ttttgttgaa tcttgaaata aaagtcttcc tttaccacat atctcccttt 300

 aatactacat ctctcttctc agccaaatac ttgggaagag aagccctgag 350

 tttgtgtcat tgttttctca cctccagttc actactttgc ccactgcctg 400

 acatccagct cgctcacaca cacacacaag cccaatcact aagttgccat 450

 agctaatttg tagctttcct gccttcctgg caaaatttga ctctgcattg 500

 ggataataca tgtcgagtac ctattgaaca ggcactgtgc taggtgctac 550

 tgttatagat atgaaaagaa ggcatcatct cctttctaac aactcacagg 600

 agcagccatt cctgattcat acatgtctct tgactcccag tgctcacttt 650

 ttcaagcttc acttaatgcc gtgcaaatca ccctattctc caggtcttct 700

 ttcttcccag ttctccttac tatacacaac ttctcaaggc agtcacctcc 750

 acacccatgg cttcaattgc tttctccatt ctctgagaac aatagaattt 800

 taaatggttt tatttcatgt attagcttta ttttatacaa ggtgcctcac 850

 ctgctgtaac catagattca aagttgctcc atgaaagtaa taaatgaaaa 900

 atggtgattt tttagcatgt aaattttagg aaatttcccc agttacgctt 950

 aatggcttga tttagtgtgt atgttatttt tgaaaacata tgttgggatg 1000

 tcacaaatgg acttagccta cagagattta tattcaactt ttgaccagag 1050

 agttccattt taatgtgaca ctgagagtaa aaaactatct tttcctcctt 1100

 acctatttct cttcctacat tctcggccag gaggaaggca ctgctacata 1150

 cccagtcttc cccagcagag cctgagcagc tctgttttcc ttctacttcc 1200

 cctcttcttt cacatctcat gaccaagcac ttcctattct gtctcccaaa 1250

 tgatcacaga ctttttcctc cacttttgtc actgccactg cccttagcat 1300

 tactctgcct ttagagaaag tctcttaatt ggtttggttg cttccttcag 1350

 tctttattat acagaccact acacgcacat ctgacagaga cttttcacct 1400

 ttttatggtt gaatgactga aattcccaga ataaaattaa aaccacccca 1450

 gcatcaaatt tgaggtcaaa tagaggtggg tttgtatccc aggttcatat 1500

 actgtccagc agtatggtct cagaaaactg acctccttaa gcctttgttt 1550

 gtgtatctgc ctaaactcat tgagagttgg gactatttca cacatacagt 1600

 gcctggcatg tagaagggac ttaatgttga aagaagggga ggcattttaa 1650

 aatccacatc aaaaaaatgt tgttctgttc gtgagccact gcgcctggcc 1700

 tgtttattct cttaagagag aaaatgaggg gattaatgga ctgtagttct 1750

 ggacaaggtg gaaaactctt aaagtggaag tactggggca agtgctctga 1800

 cagggtagga tggtgcagtc agtcccttca cccagaaatc agtagaatgt 1850

 tagcagttca gactcaaacc ttgtgaaaaa caggtggtgg aaaggaaatc 1900

 cctcacagca actggcacca taatcaagac aatgtttaca ggataaatgg 1950

 agttacctgc tttcagcccc aggtcgtagc tattgtctgc cctgctgata 2000

 tgtgataata atttgtgatc ctgttgtctt aaaatggggt cactcatctc 2050

 cagtagaatt aagtccacag tgaagttgtc cccccatccc caaagagata 2100

 aacatatatg aatgaactca cgtgataaca actactgctg cctgggatca 2150

 tgagagacct gaactgaact gataggaagt gaaaggtggc tgagataatg 2200

 agaatagacc catctgcaga ggatcataaa accagcaaag acaagatctt 2250

 gtctaagatg ccttcacaag ctttgtccat gagaactctt aaggatttca 2300

 ccagacctgt tggctgctgc tgtgatctct gcccaagagg agcctctgac 2350

 caacatccaa agggcttctg gacccactgg actcctctgg aggtaccttg 2400

 gtctcccgat ccatggctgt ggttttttac tccctttatc actgcctgtg 2450

 tgtagaatga taattgcaca attgatagtg tgaagacctc ttgataaatg 2500

 gtaaatctga gcatatgtat ttggctgaca tgtcattgtg aaacctcaca 2550

 gcttcagtca gtgtctctcc aaggactaaa caatggaaga ctgtagaaga 2600

 tgctattcat taagatatcg caagaatatg gaagactatt attcgcttct 2650

 catgggacag gacttttcag ggcacctgaa aaaactccca tgaaaaatca 2700

 cttttacaaa atgtcaagtt atgatatcca agatgaaacc aatgagtcac 2750

 aacattcaca taatacactg tacaaccctg atctcttgac tgtcatcaaa 2800

 tgtttcttac ctctaaacca aagtttcatt ttataattta atttttctca 2850

 ttttttccat tctcttagct taagaaaaga tcattacaaa ctttttgtaa 2900

 gtttttcata tatgcttgca aagggtcgta aaactttatt gtgattattc 2950

 ttgctttaag ctgaaacatc cctaatcttt ctttagagat tgtggcatag 3000

 catgttagtt tcttttccat atccaattgt tgtctgtaat gaatacagaa 3050

 atacgggcac tattttgtaa ctttaaatag acatcatctc aagtctacaa 3100

 gaattatcca aaatggtatt taatgacatt tctaggtctt cagacactat 3150

 taatgcagat tgtagcctct aggtcctgaa gattttacta gatactggtt 3200

 actgaaactg agctttcttg aattcttttt ccttccactg tggtttcccg 3250

 catttcaaca tatcacctat ttttgtcctc aaaggttact taaatttttt 3300

 ccacagaatt aaattaaata tgaatcatcc ctcctctgat ttttgaaatg 3350

 accctttgct tcctatgata atgattcttc tggtccgttt tgtagttata 3400

 tgttagagtt tgtaaatagt cacacatttt gcaactgcat gtaattttct 3450

 tattattttt tcctcttcct ctaaaactgc tgttatttct tttaactttt 3500

 tgtgggaaaa attaaaccca tctttcactt tgttgatata cttatttata 3550

 attgaactcc ttgatttttg ctcgaattgc ttttcaagtt acccactttt 3600

 agggaagaca ttatttgggt tttgtttagt gtatcaggct ttttttagtt 3650

 agttgtatca agaagtgtag acttttctat acataatatc ctttttccca 3700

 cagtagnnnn nnnnnnnnnn nnnnnnaaag tctggccgtg agcccccgca 3750

 cctggcctgt ttattctctt aagagagaaa atgaggggat tagtggactg 3800

 tagttctgga caaggtggaa aactcttaaa gtggaagtat tggggcaagt 3850

 gctctgacag gctaggatgg tgcagtcagt cccttcaccc agaaatcagt 3900

 agaatgttaa cagttcagac tcaaaccttg tgaaaacagg ttctagaaag 3950

 gaaatccctc acagcaactg gcaccataat caagacagaa tttttgcaga 4000

 ataaatagag ttacctgctt tcagccccag gtcgtagcta ttgtctgccc 4050

 tgctgatatg tgataataat ttgtgatcct gttgtcttaa aatggggtca 4100

 ctcatctcca gtagaattaa gtccacagtg aagttgtccc cccatcccca 4150

 aagagataaa catatatgaa tgaactcacg tgataacaac tactgctgcc 4200

 tgggatcatg agagacctga actgaactga taggatgtga aaggtggctg 4250

 agataatgag aatagaccca tctgcagagg atcataaaac cagcaaagac 4300

 aagatcttgt ctaagatgcc ttcacaagct ttgtccatga gaactcttaa 4350

 ggatttcacc agacctgttg ggctgctgct gtgatctctg cccaagagga 4400

 gcctctgacc aacatccaaa gggcttctgg gacccactgg gactcctctg 4450

 gagggnacct tggtctcccg atcc 4474

<210> 5094
<211> 21
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3707-3726, 4456
<223> Unknown amino acid

<400> 5094
 Tyr Val Lys Ile Lys Val Ile Lys Arg Tyr Phe Pro Lys Pro Phe
   1               5                  10                  15

 Leu Tyr Gln Lys Tyr Leu
                  20

<210> 5095
<211> 272
<212> DNA
<213> Homo sapien

<400> 5095
 caacatgaca tttctataac ttaaaaacaa caaattatat ttgtatgggt 50

 tctcttatac atattgatgt tctctgccca gtgagaacac agggtgtgtg 100

 gtagattgat gtcaaaaata tggttggatc agtcttatca ggcagaattg 150

 gaagtttctg tgtcagacca tgggaaatac cataggccat tgagcaggga 200

 agctatggtg agagtgctga tagaaatgat ttggcaagcc gggtgcggtg 250

 gcttcactcc tgtaatccca gc 272

<210> 5096
<211> 53
<212> PRT
<213> Homo sapien

<400> 5096
 Met Ser Lys Ile Trp Leu Asp Gln Ser Tyr Gln Ala Glu Leu Glu
   1               5                  10                  15

 Val Ser Val Ser Asp His Gly Lys Tyr His Arg Pro Leu Ser Arg
                  20                  25                  30

 Glu Ala Met Val Arg Val Leu Ile Glu Met Ile Trp Gln Ala Gly
                  35                  40                  45

 Cys Gly Gly Phe Thr Pro Val Ile
                  50

<210> 5097
<211> 1543
<212> DNA
<213> Homo sapien

<400> 5097
 atgaggtatt cctttgtatg gcaccccttt caagaagaaa acaaaacaaa 50

 acccaacctg tgagcctctc tgtaggcagc gtactcacca ggagacagga 100

 aagctagaag caccactagg gcccaccgca tgccttcctc tcgggggcct 150

 tggaaggaaa gggaccagat gaagaggagc agaagatcct cttaaaactc 200

 aggtcccact caacaaggaa gtgatcccta gcacagaaga cagtaggagg 250

 agctggtttc ctgagacaca ggcagagaga agtgactgaa gatgtgtctt 300

 aggggactcc caagccttcc tcccagaagg gttggtgcct gggaggacct 350

 gcagaggagc tcccgcatct cctcaggccc tttcttcggc gccctcttgt 400

 ggcagctgag agcaggccca gggcagaagg gaggcagggg cattaagagc 450

 tcaggcctcc agctgaggga ctgcagatgt tgggaagcct ctgattaggg 500

 cccggaacca acttcctttt cgcatctgca gactcatgga ggcaaccact 550

 caaggccact ctgagaaggg ttgaacgtgc tttaaattaa aaggactgag 600

 gatcatgtgt gttggtgtgt cctggactct gctctaagag ctgcacgggg 650

 gcttggatca atgcctgaat ccagtgttcc tgagtgcaga gcatctttgc 700

 tctgggtgag ctttgaccat cctggagaag aaggctgctg ccgggggtgg 750

 gacaaagcca agaccaatgc ccagcggcca agccagccag atggctctgt 800

 gctggcagcc agtgtacaca gattttacct gaaggaaaaa atgtcacatt 850

 ttccacagac aactgaagaa aaagagctct ttggattacc ctaattgtga 900

 tttactcatt ggaaccactg ttttggattg tccaaaatta agtctcaaag 950

 cttaaatatg aggcttcagg gagttatcct gaaatcagtg cttggtatct 1000

 tcttgttttt tgcttgtttt ttaaaacctt aattctcata tttttctgtc 1050

 atatttctca gtgcctggta cattatcacc attaatccat gccagttatg 1100

 tacagttttg catgtttgtt ttttatttta ctcttttctc tccttcattc 1150

 cctattcctg ttcccccata ggtgcccagt ctaatgtatt tgatatctgt 1200

 ccttagagcc tccgtatctg tgaagactag agtcatgcac ttcatcacat 1250

 ttcagtaacg atgggccgca tgtaccacag tcccatgaga tgatagaggt 1300

 gcagaaaaat tcctgtcatc tagtgacatc gtagccatca taacatcaca 1350

 acacgactct catttgtggt gaccctggtg tacacaaacc tactgtactg 1400

 ccagttgtat aaaagtctag cacatcccac gacgcacagt acatacttga 1450

 aaattataat aaatgaccat gttactggtt tatgtaatta ctatattata 1500

 ctttttaatc attattttag agtgtacaac ttctacttgt aaa 1543

<210> 5098
<211> 26
<212> PRT
<213> Homo sapien

<400> 5098
 Met Thr Met Leu Leu Val Tyr Val Ile Thr Ile Leu Tyr Phe Leu
   1               5                  10                  15

 Ile Ile Ile Leu Glu Cys Thr Thr Ser Thr Cys
                  20                  25

<210> 5099
<211> 460
<212> DNA
<213> Homo sapien

<400> 5099
 aagggaaaag cttcggggtg gttttggtcc atttctccag cgaagaagta 50

 gacatggcga gcgactcccc ggctcgaagc ctggatgaaa tagatctctc 100

 ggctctgagg gaccccgcag ggatctttga attggtggaa cttgttggaa 150

 atggaacata cgggcaagtt tataagcaaa tgaaccagtg agtgaagggc 200

 attatcacaa ctccaagaac caactaggag tcacccatga catcatctcc 250

 tgaatttcat caccaagccc agctgatcct atttcctaaa tggttcctga 300

 tttctctctt ctgttttctg tctctgccac cactgtccta gcacaggcat 350

 tgcacatctc tcatatgaac gcctgcagga ctgtcccttg atgttatcct 400

 tgcagcccct acattcctac tgtgcagcca gtaaagtcat attaaaatgc 450

 ttatttgatc 460

<210> 5100
<211> 62
<212> PRT
<213> Homo sapien

<400> 5100
 Gly Lys Ser Phe Gly Val Val Leu Val His Phe Ser Ser Glu Glu
   1               5                  10                  15

 Val Asp Met Ala Ser Asp Ser Pro Ala Arg Ser Leu Asp Glu Ile
                  20                  25                  30

 Asp Leu Ser Ala Leu Arg Asp Pro Ala Gly Ile Phe Glu Leu Val
                  35                  40                  45

 Glu Leu Val Gly Asn Gly Thr Tyr Gly Gln Val Tyr Lys Gln Met
                  50                  55                  60

 Asn Gln


<210> 5101
<211> 696
<212> DNA
<213> Homo sapien

<400> 5101
 catgagacca gcactgtgtg ggtctgaatg atggctttgg tgttcagttt 50

 agcacacgcg gtctaccacg tctgcatgag tggtaaatgt agtgcctggg 100

 tcaaaatgtt ccttctgttc aaatcgaaat acctcatctc tatggctcta 150

 tggctgtaca ttaggaccta gaacagtggc ccattgctct tagactggaa 200

 ccatgtccac taaaataaac ctaagcagat gttgtagacc tagccccaca 250

 ggactgcatt tagctgcttc agtgacactt tgatgaaagt atggagaagt 300

 ggagacatta tagataaaat atatcaattc ccagagaaaa ctcttgactt 350

 aaaaacttaa ctgtagtaaa tatatctttt tcaggtgatg aattattttt 400

 ttaaaaaagg ttacatatag gaattctgca gtataatttg gaggctatta 450

 gtgctatatt aatggaaatt aattattttt taagtaagtc caaaaaataa 500

 tctagaaagt aagtttccag agcaaatctg acctagcatt tggtatgcta 550

 ggctctgctt ttcatgattt tgaaataaat cataattaga cttaacaata 600

 tggagaaaat aaacttgtat ttttaagtgt tctgttggct tattttctgt 650

 ttcatccaac tcaataattc tgataaataa atttggttct agtttg 696

<210> 5102
<211> 47
<212> PRT
<213> Homo sapien

<400> 5102
 Met Met Ala Leu Val Phe Ser Leu Ala His Ala Val Tyr His Val
   1               5                  10                  15

 Cys Met Ser Gly Lys Cys Ser Ala Trp Val Lys Met Phe Leu Leu
                  20                  25                  30

 Phe Lys Ser Lys Tyr Leu Ile Ser Met Ala Leu Trp Leu Tyr Ile
                  35                  40                  45

 Arg Thr


<210> 5103
<211> 945
<212> DNA
<213> Homo sapien

<400> 5103
 ctaagggtgg cccactcttg tgattgcccc atttcctctg gcaacaaaag 50

 ccagagtgtt gtgggccaag tccccccaca gggcctctgc agggcatggc 100

 cctgatttcc ctggtttgag actcacttcc tcatctccct gtcctctgag 150

 ataatatgag tgagcactta ggtatcatat cagatgctca aggctggcag 200

 ctaccccctt cttgagagtc caagaacctg gagcagaaat aatttttatg 250

 tatttttgga ttaatgaatg ttaaaaacag actcagctgt ttctttcctt 300

 ttactactac cagttgctcc catgctgctc caccaggccc tgtttcggat 350

 gccaactggc ccactcccca agcacttgcc cccagcttgc gaccattggc 400

 actgggaggg cctggcttct gggctgatgg gtcagttggg ccttcataaa 450

 cactcacctg gctggctttg ccttccagga ggaagctggc tgaagcaagg 500

 gtgtggaatt ttaaatgtgt gcacagtctg gaaaactgtc agaatcagtt 550

 ttcccataaa agggtgggct agcattgcag ctgcatttgg gaccattcaa 600

 atctgtcact ctcttgtgta tattcctgtg ctattaaata tatcagggca 650

 gtgcatgtaa atcatcctga tatatttaat atatttatta tattgtcccc 700

 cgaggtgggg acagtgagtg agttctctta gtccccccag agctggttgt 750

 taaagagcct ggcacctacc cgctctcact tcatctgtgt catctctgca 800

 cactccagcc cactttctgc cttcagccat tgagtggaag ctgccccagg 850

 cccttaccag gtgcagatgc ccaatcttga tgcccagcca tcagaactgt 900

 gagccaaata aacctttttc tgtataaaaa aaaaaaaaaa aaaaa 945

<210> 5104
<211> 130
<212> PRT
<213> Homo sapien

<400> 5104
 Met Leu Lys Thr Asp Ser Ala Val Ser Phe Leu Leu Leu Leu Pro
   1               5                  10                  15

 Val Ala Pro Met Leu Leu His Gln Ala Leu Phe Arg Met Pro Thr
                  20                  25                  30

 Gly Pro Leu Pro Lys His Leu Pro Pro Ala Cys Asp His Trp His
                  35                  40                  45

 Trp Glu Gly Leu Ala Ser Gly Leu Met Gly Gln Leu Gly Leu His
                  50                  55                  60

 Lys His Ser Pro Gly Trp Leu Cys Leu Pro Gly Gly Ser Trp Leu
                  65                  70                  75

 Lys Gln Gly Cys Gly Ile Leu Asn Val Cys Thr Val Trp Lys Thr
                  80                  85                  90

 Val Arg Ile Ser Phe Pro Ile Lys Gly Trp Ala Ser Ile Ala Ala
                  95                 100                 105

 Ala Phe Gly Thr Ile Gln Ile Cys His Ser Leu Val Tyr Ile Pro
                 110                 115                 120

 Val Leu Leu Asn Ile Ser Gly Gln Cys Met
                 125                 130

<210> 5105
<211> 1253
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 285, 290, 296
<223> Unknown base

<400> 5105
 gctggctttg gcttttttat gtagaaaagg aacctattga aaagatactg 50

 attggttcca ataactgcta gaagtttctg caaaaccatg ctttgaaagt 100

 gagcaggaaa agaagagact aggctgtggc tgggagcaca gccaaaatta 150

 caaaaccagc ccagggatga tgatcctgtt catgcacagc cactgtcccc 200

 agcactaggc acagactcta ccactgcctc actgtctctg ctggacttgg 250

 aaacttgata ttactgttac tgctgcactg tctgncatgn aaatgngttg 300

 tccagggtcc cttcttcatc ctttcatctc tagcttataa ttcaaagtct 350

 gggattgagt ggccaatcct aggtcacatg tccatgtcct atctccaagg 400

 ggggctggga attgaatatc tggcattttc cactttcact tcttatgaat 450

 taaggaattc tacaaataat agaagtggga ttcaggtggt aggcagacaa 500

 aaaagcctca caattatcca ctacgccacc cttgtataac cttaccctca 550

 ttcactgtct actctcaaaa ctgtggagct actaatgaag atttgtaaac 600

 cctgggctta tgagcaccca ttcctttact acaactcaga ttgctctaga 650

 agctcagttc ccagcacttg gatttttcca gtagctgaat tctacctgaa 700

 ggaagggcag aaacaaaggg tgaagaagag gctatcactt ccaagtatcc 750

 tgcacccctg ggctcaagac ctcactgggg agggagtctt ttgggccacc 800

 caccaaacag cactggcatt atgcctctca ccctagacca tggttacacg 850

 tggtaaaaca accccttctg gtgatacatt cacaactctc tagtttcccc 900

 caaatggcac tatggggagc gggagcttgc cttttcctca gacttaaaac 950

 aataagtttt ccccgtgttt cccctctaat gctgttttct tttgaccaag 1000

 catgtctgaa ttctagagaa gtcaggagga acacacccat tctcggtttg 1050

 aagggactga tgttctgaag tacaactggg cacagtccca ggctcttcag 1100

 gacgcttcct ccattcacac agcggggatg tgattgttac agcgggtggt 1150

 gtgtgctggc tgagaagcca ctgtgaattg attcttcttc tgaagtttat 1200

 gtttctactt tttggaaatg aataaattac agccagtcca tcaaggaaat 1250

 tgc 1253

<210> 5106
<211> 83
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 285, 290, 296
<223> Unknown amino acid

<400> 5106
 Met Lys Ile Cys Lys Pro Trp Ala Tyr Glu His Pro Phe Leu Tyr
   1               5                  10                  15

 Tyr Asn Ser Asp Cys Ser Arg Ser Ser Val Pro Ser Thr Trp Ile
                  20                  25                  30

 Phe Pro Val Ala Glu Phe Tyr Leu Lys Glu Gly Gln Lys Gln Arg
                  35                  40                  45

 Val Lys Lys Arg Leu Ser Leu Pro Ser Ile Leu His Pro Trp Ala
                  50                  55                  60

 Gln Asp Leu Thr Gly Glu Gly Val Phe Trp Ala Thr His Gln Thr
                  65                  70                  75

 Ala Leu Ala Leu Cys Leu Ser Pro
                  80

<210> 5107
<211> 1283
<212> DNA
<213> Homo sapien

<400> 5107
 atgaaggctt atctgcattc attccccggc cctccctgcc gtctgcacag 50

 cctcctccag gcctcccctt cccagtgaaa agcaccacca tccagacctc 100

 aggaagcaat cattttagct tcttctcctt ctccctcacc atccaggaca 150

 tcactgagcc ctgtcagttc tgcccccaga atatctaagt tcatccaatg 200

 ccccatttcc actgctgctt cctcacccaa atcaggatgt ttctggcccc 250

 gtctccctcc tacctggtct ccctgcctgt accctcctct ccactgggcc 300

 cattctccac cggcagccag catgatctct aagaaatgta catctgtcat 350

 ctgtcatatc tgctgaaaat tgttcagggc ttcctgctgc cttgagaatg 400

 agggtctgaa tcccaaacaa gggttcaaat ctcaacctct caggcctacc 450

 ctgaccttac gtatctttcc tcagggcctg tgcacatgct gttccttctt 500

 cctggaatgc ttgtccccat agttttcagc tggcgaatgt gagtcaggtc 550

 tccccttaaa tgtcatctaa gagagccctt tctaattcct ccccttcatc 600

 ttaactctat ccccaataca ctctctcaca gagactgttc ttttccttct 650

 gagaccctac tccagcttgt agttctaaat ctgtgattat gcactgtctg 700

 tcttcctctt gaggtcaggg gccatttctt ttgttctctg ctatgctcag 750

 gacccagatc aaaggagctc agtaactatt tacaggcgta catcatatgt 800

 ggaggacact tatgctgtga tggccccaca cacagcttcc tttggggtct 850

 gtcccctgct ctccgttacc cgcgtggtag ccactgagca ctggctcttc 900

 ctggcttcac tctctggcat caaaacttat cagtcctaca tctcagtctt 950

 ttgcaaggtg acacttatct gattacctaa ttcacacgaa ggtgttaatg 1000

 gtggtaatgg catagtattt attaccccag gggacccaga acggtggtat 1050

 caaaacatat cattccccag tggtttaaaa ctctggtagc tttccaggga 1100

 gtccaagtgg agtccagtct ccttagctga gttcacaggg ccccgtctgc 1150

 acgacttggc ttctgtcggc ttccctagcc ctgacttccc aagccttagt 1200

 catcaccctc tctcccaccc agggctcagc acagtacctg gaacagtcaa 1250

 gccctcaata aatgtttact gagtgcatta aaa 1283

<210> 5108
<211> 61
<212> PRT
<213> Homo sapien

<400> 5108
 Glu Gly Leu Ser Ala Phe Ile Pro Arg Pro Ser Leu Pro Ser Ala
   1               5                  10                  15

 Gln Pro Pro Pro Gly Leu Pro Phe Pro Val Lys Ser Thr Thr Ile
                  20                  25                  30

 Gln Thr Ser Gly Ser Asn His Phe Ser Phe Phe Ser Phe Ser Leu
                  35                  40                  45

 Thr Ile Gln Asp Ile Thr Glu Pro Cys Gln Phe Cys Pro Gln Asn
                  50                  55                  60

 Ile


<210> 5109
<211> 1582
<212> DNA
<213> Homo sapien

<400> 5109
 ctcgagccga attcggctcg agagcggttc agcaggcaga ggttctcgga 50

 cgccctccgg cgaagccacc tgttgatgct tttgaccttc tgtccttgtt 100

 cctcgtccca tctggagcat ttccaattct ggttttgcgg agcagcaggt 150

 ctgagcttgt ccggcgaggg tgggagttgg tcccggcgga gatccagtgg 200

 gaagagccgg cggctgcccg ggcaactccc ccactggaaa ggattctgaa 250

 agaaatgaag tcagccctca gaaatgaagt tgactgcctg ctggctttct 300

 gttgactggc ccggagctgt actgcaagac ccttgtgagc ttccctagtc 350

 taagagtagg atgtctgctg aagtcatcca tcaggttgaa gaagcacttg 400

 atacagatga gaaggagatg ctgctctttt tgtgccggga tgttgctata 450

 gatgtggttc cacctaatgt cagggacctt ctggatattt tacgggaaag 500

 aggtaagctg tctgtcgggg acttggctga actgctctac agagtgaggc 550

 gatttgacct gctcaaacgt atcttgaaga tggacagaaa agctgtggag 600

 acccacctgc tcaggaaccc tcaccttgtt tcggactata gagtgctgat 650

 ggcagagatt ggtgaggatt tggataaatc tgatgtgtcc tcattaattt 700

 tcctcatgaa ggattacatg ggccgaggca agataagcaa ggagaagagt 750

 ttcttggacc ttgtggttga gttggagaaa ctaaatctgg ttgccccaga 800

 tcaactggat ttattagaaa aatgcctaaa gaacatccac agaatagacc 850

 tgaagacaaa aatccagaag tacaagcagt ctgttcaagg agcagggaca 900

 agttacagga atgttctcca agcagcaatc caaaagagtc tcaaggatcc 950

 ttcaaataac ttcaggatga taacacccta tgcccattgt cctgatctga 1000

 aaattcttgg aaattgttcc atgtgattaa catggaactg cctctactta 1050

 atcattctga atgattaaat cgtttcattt tctaaatgtg ttataatgtg 1100

 tttagccctt tcttgttgct gtatgtttag atgctttcca atcttttgtt 1150

 actactaata atgctataaa ataaatatcc ttgtacttct ttgtgcattt 1200

 gtttttttac tgagctaatt ttaatgattt cagcaaaagt tattttgtta 1250

 ttgagtgatg aaacaaaaga tttttgaggg tgttcatgag cataagtatc 1300

 atatagtcac ttatggttgt tgtgttccta gtacttagta caaggtatcg 1350

 gaattgttct ttagttaatc ttttatcttg agaagttaaa tcttggtgta 1400

 atcttatcct catgttcata taaagatatg tggagtttgt agtgaggact 1450

 tagagccggg tacaatttca tggttaaatt agaaatgctt ttggcagtgt 1500

 taacagctct tttagaattt gtctagcagg cttttcagtt tttgccagaa 1550

 agccctaaaa aaatagtagg aaaaaaatgc tt 1582

<210> 5110
<211> 221
<212> PRT
<213> Homo sapien

<400> 5110
 Met Ser Ala Glu Val Ile His Gln Val Glu Glu Ala Leu Asp Thr
   1               5                  10                  15

 Asp Glu Lys Glu Met Leu Leu Phe Leu Cys Arg Asp Val Ala Ile
                  20                  25                  30

 Asp Val Val Pro Pro Asn Val Arg Asp Leu Leu Asp Ile Leu Arg
                  35                  40                  45

 Glu Arg Gly Lys Leu Ser Val Gly Asp Leu Ala Glu Leu Leu Tyr
                  50                  55                  60

 Arg Val Arg Arg Phe Asp Leu Leu Lys Arg Ile Leu Lys Met Asp
                  65                  70                  75

 Arg Lys Ala Val Glu Thr His Leu Leu Arg Asn Pro His Leu Val
                  80                  85                  90

 Ser Asp Tyr Arg Val Leu Met Ala Glu Ile Gly Glu Asp Leu Asp
                  95                 100                 105

 Lys Ser Asp Val Ser Ser Leu Ile Phe Leu Met Lys Asp Tyr Met
                 110                 115                 120

 Gly Arg Gly Lys Ile Ser Lys Glu Lys Ser Phe Leu Asp Leu Val
                 125                 130                 135

 Val Glu Leu Glu Lys Leu Asn Leu Val Ala Pro Asp Gln Leu Asp
                 140                 145                 150

 Leu Leu Glu Lys Cys Leu Lys Asn Ile His Arg Ile Asp Leu Lys
                 155                 160                 165

 Thr Lys Ile Gln Lys Tyr Lys Gln Ser Val Gln Gly Ala Gly Thr
                 170                 175                 180

 Ser Tyr Arg Asn Val Leu Gln Ala Ala Ile Gln Lys Ser Leu Lys
                 185                 190                 195

 Asp Pro Ser Asn Asn Phe Arg Met Ile Thr Pro Tyr Ala His Cys
                 200                 205                 210

 Pro Asp Leu Lys Ile Leu Gly Asn Cys Ser Met
                 215                 220

<210> 5111
<211> 446
<212> DNA
<213> Homo sapien

<400> 5111
 atcactgcag ggactgcagc tatgggattt taaaaggaag tgcacagatg 50

 ggcctaggag aggactcagg ggcctgactg attaaagctt ggccaagcac 100

 agaatctttc ccactctcca gaagctcacc ctgacctctc cttttcactc 150

 aggccctgtc tctcattaac agccagtagc ttattggtga tcctagatgc 200

 agcctgcaac cttttgtaca actcacagaa gcactgattt gctgtcaaat 250

 ggtggaaaag ttcaagctgc caaacttttt cttaaaggac caaacagtga 300

 atactgtagg ccttaactgt tgcaacacca tagcctctgt tgcaacaact 350

 caactctgtc cttgtagtac aaaagcagcc actgacaata tgtccataaa 400

 tgaatgcgca tggttgtgtt ctaataaaac tttatttaca aacggg 446

<210> 5112
<211> 39
<212> PRT
<213> Homo sapien

<400> 5112
 Met Gln Pro Ala Thr Phe Cys Thr Thr His Arg Ser Thr Asp Leu
   1               5                  10                  15

 Leu Ser Asn Gly Gly Lys Val Gln Ala Ala Lys Leu Phe Leu Lys
                  20                  25                  30

 Gly Pro Asn Ser Glu Tyr Cys Arg Pro
                  35

<210> 5113
<211> 3256
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1734-1894
<223> Unknown base

<400> 5113
 cagaggcagg gaaaaccacg cagaagcagg agctgaagac ctcagaccgg 50

 caccaggaca gcttaatgaa gacaaactga aggggaaact gagatcctta 100

 gaaaaccagc tatacacctg tacccagaaa tactcccctt ggggaatgaa 150

 aaaagtacta ctggagatgg aagaccagaa aaacagctat gagcagaagg 200

 ccaaggagtc actgcagaaa gtgctggagg agaaaatgaa tgcagagcag 250

 caactacaga gcacacaggt atggggatgc cacatagaca tggggctggg 300

 gactccaggc agcttgggga acaaggggag ccagctgcac aactccctgg 350

 agccctctcc tctctgatct ccctcagcga tccctggccc tggcagagca 400

 gaagtgtgaa gagtggagga gccagtatga ggctctgaag gaggactgga 450

 ggacccttgg gacccagcac agggagctgg agagccaact ccacgtgctt 500

 cagtccaaac tgcaggtacc aggcactggg ggtggggagg gaagacaggg 550

 tatggggagg agggatggtg atgaaagaag ctgttctgga ttagggactc 600

 caaaggcagc tgacagcatc tggctttcag ttcctcagtc accactactt 650

 tgtaccaaat tcactgtttt ggctctgaaa tctaattttg agtttagcaa 700

 ggatgtctgc attgctcatg caaatgaact aagcgttcat tggaatgaca 750

 ccatcaccac ccaaatgaaa agaactggct ggaatattca tcagcctact 800

 aatgtcatct cccaacccac tctccaaact ccatcccaaa aaagcatcca 850

 gttcagaatt gcccactgtt ggcaaagaaa gaatgtcact aatttattta 900

 caggtgagta ttaacacttt ctgccaatgt gtattttaag caattacatt 950

 tagcaattac aattagattc ttggcatcct caagggttcc atcatcttca 1000

 atctgtccta agcctcagtt tcccccatct ctagaatgag gataatagta 1050

 cctacatcat aaggtggctc tgagtattaa gtaagatgat ccatgtcaag 1100

 cacttagcac aatgcctggc acacaaaaac actcagtaaa tattagctat 1150

 tattttgcat agatttattt acctggtttg gaattttgag gatccacctc 1200

 aaaagctgat ctttgtaatt ttcctgaagc agggctcaga acagcccact 1250

 tgataagaga cagagtatgt gagtcttatc aaaggagtga acccagctgg 1300

 tcactctgcg tggtatccac agctcaacct ttgttgtttt cttcttccca 1350

 tcacctataa ggcaactcct atgaagattt ttgtgagggg ttttttaact 1400

 ttaaatcttt gtggaaaaaa aaagacccta accaaaaaaa aactgatact 1450

 gccagaagta gaaaaaagag aaaatgaaaa catccagaaa actaatgact 1500

 ttgtattcct taatttggtg atttaccaaa gtgtcaagac atgactccca 1550

 caccaatgac aaccacttac atttccccta gaatggcaga ttttttaacg 1600

 tactgggttt cctaaagcaa ttcttatttt atatattcta atttatgtac 1650

 atgaatgtgt cacttagacc tgtcactagg gatggtttag aaaataaact 1700

 tacactgcac atgcctcagt ccacttcaaa actnnnnnnn nnnnnnnnnn 1750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1800

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1850

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnagacgc 1900

 gagttccttg tgaatatcaa aagtctaatc tgctgttata aatatgagga 1950

 acaaagcaaa gggaagaaat aggaaaaaag aaagacttct ctattttctc 2000

 atctccctaa cattccttct atctctaaaa ttccagactt ttctacattt 2050

 tcctcttcca tggtacccgc cccccaacct ccaccccaac actgaccatc 2100

 cttctatatt ggcccctcct cctccttaca gggagcagat agcagggact 2150

 tacagatgaa ccaggccctg cgatttttgg aaaatgagca ccaggaactg 2200

 caggccaaga ttgaatgcct gcaaggggac agagacctgt gcagcttgga 2250

 tacccaggac ctacaaggta ctcttctcct tggaggcctt gagtgcatgg 2300

 cagccatggc caagtgagct aagaaaaaag aaactgaatt aagagaaagg 2350

 cttcagcctt ttatttgttt gcttgattgg ttgattggct ttataatctc 2400

 attttacctt gagggagagg caggactgtt ttaatcatcc aaaattgaaa 2450

 attaatttca ctgtagtaga tagagtatct tgttgtctga gctctctttt 2500

 ttagcccatc cctctgggcc agatcacagc tgctcccaca tcagtcacat 2550

 atgtcaaggc cacagtccta atttgaaagg gaaaggtcag ttgaaacaca 2600

 aggcatagag aaagtctctc agtcacatcc tctgtgtccg ctgatagaga 2650

 ggactagata gtgtgtaaac acaagcctca atgcaaccca acattgttga 2700

 tgcacaaaaa cctgaggtac ttggcttctg gtttacctct tcagaactgg 2750

 gacacgaaga tagagcaact tccaatagac acacgttaaa gaccatgaca 2800

 agacagcatc tattactaat ttccatccta agtactgagt tcattaagtc 2850

 ttgggttcct ttattttggc ttgcattatt gcattttcag atcaactaaa 2900

 aaggtcagag gcagagaaac tcaccctggt gaccagagta cagcagttgc 2950

 agggtttgct tcaaaatcaa tccttacagc ttcaagaaca ggagaaactc 3000

 ttaacaaaga aaggtcagca aatttattac cacaaattct aagatattgc 3050

 tcttctctta cctgcctaga ggcagcggga tggactacat gacctcctgg 3100

 agtcccagcc agttctggga gtctgttaag tccgggatgt gtgggagctt 3150

 tttaaggact gatcattggc tctgaggaca cttcaactag ttagccttct 3200

 atcttgaggt atataaactg tgaaaagggt tctattctct ctgaaagcac 3250

 atgtct 3256

<210> 5114
<211> 121
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1734-1894
<223> Unknown amino acid

<400> 5114
 Arg Gly Arg Glu Asn His Ala Glu Ala Gly Ala Glu Asp Leu Arg
   1               5                  10                  15

 Pro Ala Pro Gly Gln Leu Asn Glu Asp Lys Leu Lys Gly Lys Leu
                  20                  25                  30

 Arg Ser Leu Glu Asn Gln Leu Tyr Thr Cys Thr Gln Lys Tyr Ser
                  35                  40                  45

 Pro Trp Gly Met Lys Lys Val Leu Leu Glu Met Glu Asp Gln Lys
                  50                  55                  60

 Asn Ser Tyr Glu Gln Lys Ala Lys Glu Ser Leu Gln Lys Val Leu
                  65                  70                  75

 Glu Glu Lys Met Asn Ala Glu Gln Gln Leu Gln Ser Thr Gln Val
                  80                  85                  90

 Trp Gly Cys His Ile Asp Met Gly Leu Gly Thr Pro Gly Ser Leu
                  95                 100                 105

 Gly Asn Lys Gly Ser Gln Leu His Asn Ser Leu Glu Pro Ser Pro
                 110                 115                 120

 Leu


<210> 5115
<211> 903
<212> DNA
<213> Homo sapien

<400> 5115
 ggcttaactg gtacatctgg actctgatga gtgagaagtc caagcaaata 50

 gaaaagccac agccaaacga taaaactctg caaagacaat gtctagcact 100

 tatatctcca gtaactcctg tcaaggttta ttgttgcttg ttcatcattg 150

 cagtcctgac tacaagtgtg attgcacttt ctattgtttt gtcagaattt 200

 cctgaaaaga tacaaaggcc cttctgacca ttggattggc cttagaagag 250

 aatcatccca tcgcatttgg aaatggacag acaacatgga atataataac 300

 atttttcaca catttacaaa acaatttggg aggaggctgg aaatcatctt 350

 gactgaagac caccaatggc agcagttcat ttgggcttgc tatcagagga 400

 agtggagaat gtgccttcct gaatgacaat ggagtcaaca gtggcagaat 450

 ctacatgaac agaaaatgga tttgtagcaa gccaaacaat tatgtctaca 500

 gttgccagtt atgtccccac tgggatacta cctagtagag ctgtgagaag 550

 agggccacca tcctccagac tccagaatgg tggaatcatc agcagcttcc 600

 accatgcccc tggaaaaact gcaagtaaca gacctgcaca tgtatcccct 650

 acatctaaaa taaaagttgg aaaaaatgga actttgatgt taagatgcac 700

 tgatacaaaa cttaaatttg ggtctcctac attaaaacaa tatgagtctc 750

 ttaaaatatt gatctgtctt agtaagatta caagaggctt gatttttaat 800

 tctgcaatgt tcccttaaca gccattctga attacaaact aaattcctat 850

 ttctgcacat tccttggtga gaactgtcta gtcctgggtt ggggattatc 900

 tta 903

<210> 5116
<211> 108
<212> PRT
<213> Homo sapien

<400> 5116
 Met Ser Thr Val Ala Ser Tyr Val Pro Thr Gly Ile Leu Pro Ser
   1               5                  10                  15

 Arg Ala Val Arg Arg Gly Pro Pro Ser Ser Arg Leu Gln Asn Gly
                  20                  25                  30

 Gly Ile Ile Ser Ser Phe His His Ala Pro Gly Lys Thr Ala Ser
                  35                  40                  45

 Asn Arg Pro Ala His Val Ser Pro Thr Ser Lys Ile Lys Val Gly
                  50                  55                  60

 Lys Asn Gly Thr Leu Met Leu Arg Cys Thr Asp Thr Lys Leu Lys
                  65                  70                  75

 Phe Gly Ser Pro Thr Leu Lys Gln Tyr Glu Ser Leu Lys Ile Leu
                  80                  85                  90

 Ile Cys Leu Ser Lys Ile Thr Arg Gly Leu Ile Phe Asn Ser Ala
                  95                 100                 105

 Met Phe Pro


<210> 5117
<211> 3797
<212> DNA
<213> Homo sapien

<400> 5117
 cctttgcaga aacacccgaa accctcctgc caggaagacc agggcctggg 50

 aagagggtcg ctctccggcc attctcccct caccctcctc accttcctca 100

 catcctgtgc cctgggggac cagcagctgc ttccacccag aacaagcggg 150

 agcctgtgtc aggaaagcat gtcagagcag agctgccaga tgtccgaact 200

 gcggctcctc ctcctgggga aatgccgctc gggaaaaagt gccacaggaa 250

 atgccattct gggcaaacat gtgttcaagt ccaagttcag tgatcagaca 300

 gtgatcaaaa tgtgccagag agagagttgg gtcctgagag aaaggaaggt 350

 tgtggtaatt gacacccctg accttttctc ctcaatagct tgtgctgaag 400

 acaagcaacg caacatccaa cactgcttgg agctctctgc tcccagcctc 450

 catgctctgc tcttggtaat tgccatcggc catttcacaa gggaggatga 500

 ggaaacagcc aagggcatcc aacaagtgtt tggagctgaa gccaggaggc 550

 acatcattat tgtcttcact cggaaggatg atttggggga tgacttgctg 600

 caagatttca ttgaaaaaaa caaacctctc aagcagttgg ttcaagacta 650

 tgagggccga tactgcattt tcaacaacaa gaccaatagt aaggatgagc 700

 agatcaccca ggtgttggag ctccttcgca aggttgagtc tttggtgaat 750

 acgaacggag gaccctatca tgtgaacttc aaaactgaag gcagcaggtt 800

 tcaagattgt gtgaatgaag ctgcatctca agagggagac aagccacagg 850

 gcccaaggga aaggcagctg cagtccacag gacccgagca gaatccgggg 900

 acatcagaac tgacagtcct ccttgtgggg aaacgcggtg ctggaaaaag 950

 tgcagcagga aacagcattc tggggaggca ggcctttcag accggattta 1000

 gtgagcagtc agtaacccag agcttcttgt ctgagagcag aagctggaga 1050

 aaaaagaaag tttcgatcat tgatgctccg gacatctcat ctttaaagaa 1100

 cattgactca gaagttagaa aacacatctg tacaggcccc catgccttcc 1150

 tgctggtgac accactgggc ttttacacta agaatgatga ggcagtgctg 1200

 agcaccatcc aaaacaattt tggagaaaaa ttctttgagt acatgatcat 1250

 acttcttacc aggaaagaag atttagggga tcaggatcta gatacgttct 1300

 taagaaacag caataaagct ctctatggtc tcatccagaa gtgtaaaaac 1350

 agatatagtg ccttcaacta ccgggcaaca ggagaagaag agcaaaggca 1400

 ggcggacgag ctcctggaaa aaattgagag catggtgcat cagaatggga 1450

 acaagcattg cgttttcaga gaaaaagaaa ccctgaacat tgtccttgtg 1500

 gggagaagcg ggactgggaa gagtgcgacc gggaactcta tcctggggag 1550

 cctcgtcttc acctctcggc tccgggccca gccagtcacc aagaccagcc 1600

 agagtggcag gaggacatgg gacggacagg aggtggtggt tgtggacact 1650

 ccttccttca accagatgct ggatgtcgaa aaggacccat cccggttaga 1700

 agaggaggtc aagcgctgtt tgtcctgctg tgaaaaaggg gacacatttt 1750

 ttgtcctggt gttccagctg ggacgattca ctgaagagga caaaacagct 1800

 gtggcgaaac tggaggccat ctttggagca gactttacga aatacgcgat 1850

 tatgctgttc acccggaagg aagacctagg ggcggggaat ttggaagact 1900

 tcatgaagaa ctcagataac aaagcccttc ggcgcatttt taaaaagtgt 1950

 gggcggcgag tttgtgcttt taacaacaaa gaaacaggcc aggcccagga 2000

 aacccaggtg aaagctcttt taacaaaggt caatgatctg agaaaagaaa 2050

 gtgggtggtc cgggtatccc catacacagg agaacgtcag caaactaatt 2100

 aaaaatgtcc aggaaatgtc ccaagccgaa aaactcctta aaaatttaat 2150

 aggtatttta caataggtag ccgaagtgcc tggggtctct tcaattagag 2200

 acaccctcag gttgggggga ggggcggggc atggtacaac ctgtgggaag 2250

 ggaagcgggt tcatggcttt gagggcctga gaggcaaatg catcccgcct 2300

 tgtgatgtat cagctatttg tagataaata aattgcaggt gggggcgaat 2350

 agtagggtat tataaaggag aaagaagata caaggtgggg aaatctggaa 2400

 aaagatttca gacattaggc tgataataag tggtagaatc aagtcacaag 2450

 aatcacctca cttgtgtagg taggttggaa tcaggataga cactgtgatc 2500

 aaggctgagg ccacctggga tgagaatata gatagtcgta caacaaccca 2550

 ggggatccag atacatgaga ccagggcagc gttcagcaca ctcctgggca 2600

 tggcggaagc aggaagcaga ctccagaggg cctccctgtt gtccagggcc 2650

 gttggctccc tgagctctcc tgtctccttt gggatgcgac ttagggctag 2700

 agtgttcttt tcttcacacg ttagccattc cttacggctc ttcacgttcc 2750

 acgcctagat gtgaagtggg acatagtctt ccattgctgg ctgtccctga 2800

 ggaaacagac atgagtcttg gaggttctga atgattttat tgctaattat 2850

 cacagtgaca tagactagaa cagaaattag aagcatagta agattgccaa 2900

 aatcagagaa tcttgcaaag ttctgtaatt ctaagtgttg ttctagattt 2950

 cctctagaga aggttattag aatctccatt gcgtttctct ttctccttct 3000

 ctttcccttg aggttaggaa acaggttaaa actcagagaa ctccaataat 3050

 aatggtttaa aaacatcagg ggcttcctgt atctcctgtc aggaagccga 3100

 ggaataagca ggctggggct ggtgggcgtc aacatcccag ttttgttcta 3150

 tctttctgtc ccacctgcac tgggatgtgg cttctacact cgaatttgct 3200

 tcttggtttc aagacagtgg tgttctttcc atagctgagc agattatttt 3250

 gagaggtggg tgatatgtga gagagaaatc tggaaccttc ttctgggtag 3300

 atacaggata agatagatac agggtaaaat gttgagcact ttgtacatgc 3350

 tttgagagca taatctttgt catctgtttt tttcccctag acaatatcag 3400

 gttaccgtca acattaatcc atttaaaagg acatggactg ttgccattaa 3450

 tacttttgga ttccatataa cccttaacac aataacttct agaaaatgtg 3500

 tgtgccgtag acacaaagaa gggaacaata gacaccaggg tatacttgag 3550

 ggtggagggt ggcaggaggg tgaagattga aaagctgcct attgcgtgtt 3600

 atgctggttt cctgggtgac aaaattacct gtacaccaca cccctgtgac 3650

 acacaactta ctcatgtaac aaacctgtgc atgtacccct tgaacctgaa 3700

 ataaaaattg gaaagtaaaa aaaagtgtgt aaatatattt agttgaatca 3750

 aataataaag atgaatcatt atgaattcaa aaaaaaaaaa aaaaaaa 3797

<210> 5118
<211> 665
<212> PRT
<213> Homo sapien

<400> 5118
 Met Ser Glu Gln Ser Cys Gln Met Ser Glu Leu Arg Leu Leu Leu
   1               5                  10                  15

 Leu Gly Lys Cys Arg Ser Gly Lys Ser Ala Thr Gly Asn Ala Ile
                  20                  25                  30

 Leu Gly Lys His Val Phe Lys Ser Lys Phe Ser Asp Gln Thr Val
                  35                  40                  45

 Ile Lys Met Cys Gln Arg Glu Ser Trp Val Leu Arg Glu Arg Lys
                  50                  55                  60

 Val Val Val Ile Asp Thr Pro Asp Leu Phe Ser Ser Ile Ala Cys
                  65                  70                  75

 Ala Glu Asp Lys Gln Arg Asn Ile Gln His Cys Leu Glu Leu Ser
                  80                  85                  90

 Ala Pro Ser Leu His Ala Leu Leu Leu Val Ile Ala Ile Gly His
                  95                 100                 105

 Phe Thr Arg Glu Asp Glu Glu Thr Ala Lys Gly Ile Gln Gln Val
                 110                 115                 120

 Phe Gly Ala Glu Ala Arg Arg His Ile Ile Ile Val Phe Thr Arg
                 125                 130                 135

 Lys Asp Asp Leu Gly Asp Asp Leu Leu Gln Asp Phe Ile Glu Lys
                 140                 145                 150

 Asn Lys Pro Leu Lys Gln Leu Val Gln Asp Tyr Glu Gly Arg Tyr
                 155                 160                 165

 Cys Ile Phe Asn Asn Lys Thr Asn Ser Lys Asp Glu Gln Ile Thr
                 170                 175                 180

 Gln Val Leu Glu Leu Leu Arg Lys Val Glu Ser Leu Val Asn Thr
                 185                 190                 195

 Asn Gly Gly Pro Tyr His Val Asn Phe Lys Thr Glu Gly Ser Arg
                 200                 205                 210

 Phe Gln Asp Cys Val Asn Glu Ala Ala Ser Gln Glu Gly Asp Lys
                 215                 220                 225

 Pro Gln Gly Pro Arg Glu Arg Gln Leu Gln Ser Thr Gly Pro Glu
                 230                 235                 240

 Gln Asn Pro Gly Thr Ser Glu Leu Thr Val Leu Leu Val Gly Lys
                 245                 250                 255

 Arg Gly Ala Gly Lys Ser Ala Ala Gly Asn Ser Ile Leu Gly Arg
                 260                 265                 270

 Gln Ala Phe Gln Thr Gly Phe Ser Glu Gln Ser Val Thr Gln Ser
                 275                 280                 285

 Phe Leu Ser Glu Ser Arg Ser Trp Arg Lys Lys Lys Val Ser Ile
                 290                 295                 300

 Ile Asp Ala Pro Asp Ile Ser Ser Leu Lys Asn Ile Asp Ser Glu
                 305                 310                 315

 Val Arg Lys His Ile Cys Thr Gly Pro His Ala Phe Leu Leu Val
                 320                 325                 330

 Thr Pro Leu Gly Phe Tyr Thr Lys Asn Asp Glu Ala Val Leu Ser
                 335                 340                 345

 Thr Ile Gln Asn Asn Phe Gly Glu Lys Phe Phe Glu Tyr Met Ile
                 350                 355                 360

 Ile Leu Leu Thr Arg Lys Glu Asp Leu Gly Asp Gln Asp Leu Asp
                 365                 370                 375

 Thr Phe Leu Arg Asn Ser Asn Lys Ala Leu Tyr Gly Leu Ile Gln
                 380                 385                 390

 Lys Cys Lys Asn Arg Tyr Ser Ala Phe Asn Tyr Arg Ala Thr Gly
                 395                 400                 405

 Glu Glu Glu Gln Arg Gln Ala Asp Glu Leu Leu Glu Lys Ile Glu
                 410                 415                 420

 Ser Met Val His Gln Asn Gly Asn Lys His Cys Val Phe Arg Glu
                 425                 430                 435

 Lys Glu Thr Leu Asn Ile Val Leu Val Gly Arg Ser Gly Thr Gly
                 440                 445                 450

 Lys Ser Ala Thr Gly Asn Ser Ile Leu Gly Ser Leu Val Phe Thr
                 455                 460                 465

 Ser Arg Leu Arg Ala Gln Pro Val Thr Lys Thr Ser Gln Ser Gly
                 470                 475                 480

 Arg Arg Thr Trp Asp Gly Gln Glu Val Val Val Val Asp Thr Pro
                 485                 490                 495

 Ser Phe Asn Gln Met Leu Asp Val Glu Lys Asp Pro Ser Arg Leu
                 500                 505                 510

 Glu Glu Glu Val Lys Arg Cys Leu Ser Cys Cys Glu Lys Gly Asp
                 515                 520                 525

 Thr Phe Phe Val Leu Val Phe Gln Leu Gly Arg Phe Thr Glu Glu
                 530                 535                 540

 Asp Lys Thr Ala Val Ala Lys Leu Glu Ala Ile Phe Gly Ala Asp
                 545                 550                 555

 Phe Thr Lys Tyr Ala Ile Met Leu Phe Thr Arg Lys Glu Asp Leu
                 560                 565                 570

 Gly Ala Gly Asn Leu Glu Asp Phe Met Lys Asn Ser Asp Asn Lys
                 575                 580                 585

 Ala Leu Arg Arg Ile Phe Lys Lys Cys Gly Arg Arg Val Cys Ala
                 590                 595                 600

 Phe Asn Asn Lys Glu Thr Gly Gln Ala Gln Glu Thr Gln Val Lys
                 605                 610                 615

 Ala Leu Leu Thr Lys Val Asn Asp Leu Arg Lys Glu Ser Gly Trp
                 620                 625                 630

 Ser Gly Tyr Pro His Thr Gln Glu Asn Val Ser Lys Leu Ile Lys
                 635                 640                 645

 Asn Val Gln Glu Met Ser Gln Ala Glu Lys Leu Leu Lys Asn Leu
                 650                 655                 660

 Ile Gly Ile Leu Gln
                 665

<210> 5119
<211> 616
<212> DNA
<213> Homo sapien

<400> 5119
 gactggaaga aaaatgtttc ccaagcaacc agctttattc tagctgactc 50

 actttgtact ccctccttcc atgtcattgc tcctttttac ctctttagga 100

 gtctgttagg aattttgcaa cctgacaaaa ggcttctgca gagccaacca 150

 cctttttttt cctcagggcc tgaaaaaaaa gtgagtcttc ctactgacag 200

 gaaaataaaa agagaccttg ttagtcaatt tttttctgta tgttcaattg 250

 ttctggtata ttcttttcct tgagtataaa ggaaaagtct gaaaataatg 300

 gtaaaacgtg tgagattgct ctgatatttc ctttttgtac tttaggaggt 350

 ggttctttga gttcctagtt gtttagttga acatgaagca ggtggcaaat 400

 gtaagtttag tctacacact gattccttcc tgttcgcaga agggttcatg 450

 tgttcgtttt taaataatct tcgggtaagg aatagagaaa caccaagccc 500

 aagaggcaga aggatctgtc tatagctaat gagtgagaaa ctaactgtgg 550

 gatggtttat ggtctctggc tctttgaaac cacagaaatt taaagttatt 600

 tttaaaaagc caactt 616

<210> 5120
<211> 90
<212> PRT
<213> Homo sapien

<400> 5120
 Asp Trp Lys Lys Asn Val Ser Gln Ala Thr Ser Phe Ile Leu Ala
   1               5                  10                  15

 Asp Ser Leu Cys Thr Pro Ser Phe His Val Ile Ala Pro Phe Tyr
                  20                  25                  30

 Leu Phe Arg Ser Leu Leu Gly Ile Leu Gln Pro Asp Lys Arg Leu
                  35                  40                  45

 Leu Gln Ser Gln Pro Pro Phe Phe Ser Ser Gly Pro Glu Lys Lys
                  50                  55                  60

 Val Ser Leu Pro Thr Asp Arg Lys Ile Lys Arg Asp Leu Val Ser
                  65                  70                  75

 Gln Phe Phe Ser Val Cys Ser Ile Val Leu Val Tyr Ser Phe Pro
                  80                  85                  90

<210> 5121
<211> 1907
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1340-1396
<223> Unknown base

<400> 5121
 tgtgtttatg cttcatacaa agttgaatga ttgattggcg tggtggacat 50

 ataccatcat gctcattttt tttttttaaa gctttttaaa atgccacctc 100

 atggaggcga gggggaggag aagctcattt tacacaattc agtagttaaa 150

 tatggactcg gtctcaactt ggaattctta tgctttgaga acaaatcaac 200

 aaccagaata tttattggaa tctagctttt attataagaa ggacccaaag 250

 attatatcct gagcaaatgc acactcccca tgtgaggaca tgaagtattt 300

 acttggtgaa tgtttatgtt cttggtataa tctaggaacc ctatgagttt 350

 atctcagagt gaactaattc tagatttgtt gtcaatagat gctataattc 400

 aagaatgttg ctctccatat ttgaaaaacg atggatagga gggtgaggga 450

 agcatacaat gttgaaccag tttctcttat ttaaatatta aatactttaa 500

 gcctttaaag tgaagttgat gctagctgca aacatttact cttgtattta 550

 tcttcactag gaaactgtgg actgtaattt attttattaa atatttagaa 600

 gattatttgg cttgtgtgtt caggtgagaa atactgagtt gtttttgttt 650

 aatttcatgg tttttttttt ttaatgatcc ctagtggggg aaggggaaag 700

 gaatagtctg ataaacagat gtgcatattt taaaaacaag tgaccttttg 750

 ggaatgtagg catttagacg atgattttag tcgcactagg ggtgggattc 800

 aaactactgg tcaaagacca tttggtaaag aaaagggaac atctccgatg 850

 ggtgttaagg taggattttc catgcagccc tttatgtctg agaaatagtc 900

 tcctctgcca ttggggtccc tgcggaatct tctacaggaa ttgcagctct 950

 tcacgtcatg ctaggttacc agcatgggct tcccagagca cttccactct 1000

 gtttctaact ccactgactt ttctgacttg tttcttgagg gacttggaaa 1050

 aggggaaggt attattcaca cagatgtgtg tatgaagcct aaataacatc 1100

 caactttttt tccaaaaaca tagtaagagt ttaaccataa atggaaaaga 1150

 aaatgtattc aaaatactta aatcaaaact agaagatggg gaaaaaaaga 1200

 tttattctat acaaagcctt gtctggacca ctttagagag acttctattt 1250

 ttttaaccct tctataaata tttgatggca cttgaaatat tcctgcaata 1300

 aaatgtgatt tgtgtaaaga aaaaaagatt ttgtaatgtn nnnnnnnnnn 1350

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnntttg 1400

 tattattttc ttgatggaat ttgtctatct gtctttggaa aactttttat 1450

 ttcattgaat gtgccatagt agaaatgtgt gtttttagtt ttagactaag 1500

 gaatagctag ttgttgtgtt ccgacattcc aaaatgcaaa acaacctagt 1550

 agtatctttc atgaaaaggt ttaagtagta tgtaagcttc tctcattgtt 1600

 gcttttttgc acatgttctt cattcctctc tagtgcaata tgtacataga 1650

 gcacttgcgg gtgtaccttg atccctcagg gaaaaataca tatttgtaca 1700

 gttttttggg gtttttttgt tttttggttt tttttgtttt gccttttgtt 1750

 tttggctaag gaatgtcgat cgaatcactt gttattgttg aggggcagcc 1800

 agataataat cctaaagcca ctgtttccaa cattgattgt ttaaatcata 1850

 tgtccttcca atgctattat tttaagataa taataaaaag ttattttctg 1900

 acaaaaa 1907

<210> 5122
<211> 47
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1340-1396
<223> Unknown amino acid

<400> 5122
 Met Ser Ile Glu Ser Leu Val Ile Val Glu Gly Gln Pro Asp Asn
   1               5                  10                  15

 Asn Pro Lys Ala Thr Val Ser Asn Ile Asp Cys Leu Asn His Met
                  20                  25                  30

 Ser Phe Gln Cys Tyr Tyr Phe Lys Ile Ile Ile Lys Ser Tyr Phe
                  35                  40                  45

 Leu Thr


<210> 5123
<211> 2532
<212> DNA
<213> Homo sapien

<400> 5123
 ccggggcggc ggttgcatca gattctagga agtgtctgta gccgcagctg 50

 cgggtccggg attcccagcc atggcagatt cctccgggca gcagggcaaa 100

 ggccggcgtg tgcagcccca gtggtcccct cctgctggga cccagccatg 150

 cagactccac ctttacaaca gcctcaccag gaacaaggaa gtgttcatac 200

 ctcaagatgg gaaaaaggtg acgtggtatt gctgtgggcc aaccgtctat 250

 gacgcatctc acatggggca cgccaggtcc tacatctctt ttgatatctt 300

 gagaagagtg ttgaaggatt acttcaaatt tgatgtcttt tattgcatga 350

 acattacgga tattgatgac aagatcatca agagggcccg gcagaaccac 400

 ctgttcgagc agtatcggga gaagaggcct gaagcggcac agctcttgga 450

 ggatgttcag gccgccctga agccattttc agtaaaatta aatgagacca 500

 cggatcccga taaaaagcag atgctcgaac ggattcagca cgcagtgcag 550

 cttgccacag agccacttga gaaagctgtg cagtccagac tcacgggaga 600

 ggaagtcaac agctgtgtgg aggtgttgct ggaagaagcc aaggatttgc 650

 tctctgactg gctggattct acacttggct gtgatgtcac tgacaattcc 700

 atcttctcca agctgcccaa gttctgggag ggggacttcc acagagacat 750

 ggaagctctg aatgttctcc ctccagatgt cttaacccgg gttagtgagt 800

 atgtgccaga aattgtgaac tttgtccaga agattgtgga caacggttac 850

 ggctatgtct ccaatgggtc tgtctacttt gatacagcga agtttgcttc 900

 tagcgagaag cactcctatg ggaagctggt gcctgaggcc gttggagatc 950

 agaaagccct tcaagaaggg gaaggtgacc tgagcatctc tgcagaccgc 1000

 ctgagtgaga agcgctctcc caacgacttt gccttatgga aggcctctaa 1050

 gcccggagaa ccgtcctggc cgtgcccttg gggaaagggt cgtccgggct 1100

 ggcatatcga gtgctcggcc atggcaggca ccctcctagg ggcttcgatg 1150

 gacattcacg gaggtgggtt cgacctccgg ttcccccacc atgacaatga 1200

 gctggcacag tcggaggcct actttgaaaa cgactgctgg gtcaggtact 1250

 tcctgcacac aggccacctg accattgcag gctgcaaaat gtcaaagtca 1300

 ctaaaaaact tcatcaccat taaagatgcc ttgaaaaagc actcagcacg 1350

 gcagttgcgg ctggccttcc tcatgcactc gtggaaggac accctggact 1400

 actccagcaa caccatggag tcagcgcttc aatatgagaa gttcttgaat 1450

 gagtttttct taaatgtgaa agatatcctt cgcgctcctg ttgacatcac 1500

 tggtcagttt gagaagtggg gagaagaaga agcagaactg aataagaact 1550

 tttatgacaa gaagacagca attcacaaag ccctctgtga caatgttgac 1600

 acccgcaccg tcatggaaga gatgcgggcc ttggtcagtc agtgcaacct 1650

 ctatatggca gcccggaaag ccgtgaggaa gaggcccaac caggctctgc 1700

 tggagaacat cgccctgtac ctcacccata tgctgaagat ctttggggcc 1750

 gtagaagagg acagctccct gggattcccg gtcggagggc ctggaaccag 1800

 cctcagtctc gaggccacag tcatgcccta ccttcaggtg ttatcagaat 1850

 tccgagaagg agtgcggaag attgcccgag agcaaaaagt ccctgagatt 1900

 ctgcagctca gcgatgccct gcgggacaac atcctgcctg agcttggggt 1950

 gcggtttgaa gaccacgaag gactgcccac agtggtgaaa ctggtagaca 2000

 gaaacacctt attaaaagag agagaagaaa agagacgggt tgaagaggag 2050

 aagaggaaga agaaagagga ggcggcccgg aggaaacagg aacaagaagc 2100

 agcaaagctg gccaagatga agattccccc cagtgagatg ttcttgtcag 2150

 aaaccgacaa atactccaag tttgatgaaa atgtaagcat ggtctgccca 2200

 cacatgacat ggagggcaaa gagctcagca aagggcaagc caagaagctg 2250

 aagaagctct tcgaggctca ggagaagctc tacaaggaat atctgcagat 2300

 ggcccagaat ggaagcttcc agtgaggggg cacaggactg actttttaaa 2350

 ccattgtgga ctagtggctg ctgtctgcct cagtgacaat gtcccagcgc 2400

 tcctatcatg tttacagtca cccttgggtc ctaaattaag agttgtgttc 2450

 atgtaggttc gtgtcgtcgt tggctctgag acattgataa taaatttttc 2500

 tcaacagtga aaaaaaaaaa aaaaaaaaaa aa 2532

<210> 5124
<211> 726
<212> PRT
<213> Homo sapien

<400> 5124
 Met Ala Asp Ser Ser Gly Gln Gln Gly Lys Gly Arg Arg Val Gln
   1               5                  10                  15

 Pro Gln Trp Ser Pro Pro Ala Gly Thr Gln Pro Cys Arg Leu His
                  20                  25                  30

 Leu Tyr Asn Ser Leu Thr Arg Asn Lys Glu Val Phe Ile Pro Gln
                  35                  40                  45

 Asp Gly Lys Lys Val Thr Trp Tyr Cys Cys Gly Pro Thr Val Tyr
                  50                  55                  60

 Asp Ala Ser His Met Gly His Ala Arg Ser Tyr Ile Ser Phe Asp
                  65                  70                  75

 Ile Leu Arg Arg Val Leu Lys Asp Tyr Phe Lys Phe Asp Val Phe
                  80                  85                  90

 Tyr Cys Met Asn Ile Thr Asp Ile Asp Asp Lys Ile Ile Lys Arg
                  95                 100                 105

 Ala Arg Gln Asn His Leu Phe Glu Gln Tyr Arg Glu Lys Arg Pro
                 110                 115                 120

 Glu Ala Ala Gln Leu Leu Glu Asp Val Gln Ala Ala Leu Lys Pro
                 125                 130                 135

 Phe Ser Val Lys Leu Asn Glu Thr Thr Asp Pro Asp Lys Lys Gln
                 140                 145                 150

 Met Leu Glu Arg Ile Gln His Ala Val Gln Leu Ala Thr Glu Pro
                 155                 160                 165

 Leu Glu Lys Ala Val Gln Ser Arg Leu Thr Gly Glu Glu Val Asn
                 170                 175                 180

 Ser Cys Val Glu Val Leu Leu Glu Glu Ala Lys Asp Leu Leu Ser
                 185                 190                 195

 Asp Trp Leu Asp Ser Thr Leu Gly Cys Asp Val Thr Asp Asn Ser
                 200                 205                 210

 Ile Phe Ser Lys Leu Pro Lys Phe Trp Glu Gly Asp Phe His Arg
                 215                 220                 225

 Asp Met Glu Ala Leu Asn Val Leu Pro Pro Asp Val Leu Thr Arg
                 230                 235                 240

 Val Ser Glu Tyr Val Pro Glu Ile Val Asn Phe Val Gln Lys Ile
                 245                 250                 255

 Val Asp Asn Gly Tyr Gly Tyr Val Ser Asn Gly Ser Val Tyr Phe
                 260                 265                 270

 Asp Thr Ala Lys Phe Ala Ser Ser Glu Lys His Ser Tyr Gly Lys
                 275                 280                 285

 Leu Val Pro Glu Ala Val Gly Asp Gln Lys Ala Leu Gln Glu Gly
                 290                 295                 300

 Glu Gly Asp Leu Ser Ile Ser Ala Asp Arg Leu Ser Glu Lys Arg
                 305                 310                 315

 Ser Pro Asn Asp Phe Ala Leu Trp Lys Ala Ser Lys Pro Gly Glu
                 320                 325                 330

 Pro Ser Trp Pro Cys Pro Trp Gly Lys Gly Arg Pro Gly Trp His
                 335                 340                 345

 Ile Glu Cys Ser Ala Met Ala Gly Thr Leu Leu Gly Ala Ser Met
                 350                 355                 360

 Asp Ile His Gly Gly Gly Phe Asp Leu Arg Phe Pro His His Asp
                 365                 370                 375

 Asn Glu Leu Ala Gln Ser Glu Ala Tyr Phe Glu Asn Asp Cys Trp
                 380                 385                 390

 Val Arg Tyr Phe Leu His Thr Gly His Leu Thr Ile Ala Gly Cys
                 395                 400                 405

 Lys Met Ser Lys Ser Leu Lys Asn Phe Ile Thr Ile Lys Asp Ala
                 410                 415                 420

 Leu Lys Lys His Ser Ala Arg Gln Leu Arg Leu Ala Phe Leu Met
                 425                 430                 435

 His Ser Trp Lys Asp Thr Leu Asp Tyr Ser Ser Asn Thr Met Glu
                 440                 445                 450

 Ser Ala Leu Gln Tyr Glu Lys Phe Leu Asn Glu Phe Phe Leu Asn
                 455                 460                 465

 Val Lys Asp Ile Leu Arg Ala Pro Val Asp Ile Thr Gly Gln Phe
                 470                 475                 480

 Glu Lys Trp Gly Glu Glu Glu Ala Glu Leu Asn Lys Asn Phe Tyr
                 485                 490                 495

 Asp Lys Lys Thr Ala Ile His Lys Ala Leu Cys Asp Asn Val Asp
                 500                 505                 510

 Thr Arg Thr Val Met Glu Glu Met Arg Ala Leu Val Ser Gln Cys
                 515                 520                 525

 Asn Leu Tyr Met Ala Ala Arg Lys Ala Val Arg Lys Arg Pro Asn
                 530                 535                 540

 Gln Ala Leu Leu Glu Asn Ile Ala Leu Tyr Leu Thr His Met Leu
                 545                 550                 555

 Lys Ile Phe Gly Ala Val Glu Glu Asp Ser Ser Leu Gly Phe Pro
                 560                 565                 570

 Val Gly Gly Pro Gly Thr Ser Leu Ser Leu Glu Ala Thr Val Met
                 575                 580                 585

 Pro Tyr Leu Gln Val Leu Ser Glu Phe Arg Glu Gly Val Arg Lys
                 590                 595                 600

 Ile Ala Arg Glu Gln Lys Val Pro Glu Ile Leu Gln Leu Ser Asp
                 605                 610                 615

 Ala Leu Arg Asp Asn Ile Leu Pro Glu Leu Gly Val Arg Phe Glu
                 620                 625                 630

 Asp His Glu Gly Leu Pro Thr Val Val Lys Leu Val Asp Arg Asn
                 635                 640                 645

 Thr Leu Leu Lys Glu Arg Glu Glu Lys Arg Arg Val Glu Glu Glu
                 650                 655                 660

 Lys Arg Lys Lys Lys Glu Glu Ala Ala Arg Arg Lys Gln Glu Gln
                 665                 670                 675

 Glu Ala Ala Lys Leu Ala Lys Met Lys Ile Pro Pro Ser Glu Met
                 680                 685                 690

 Phe Leu Ser Glu Thr Asp Lys Tyr Ser Lys Phe Asp Glu Asn Val
                 695                 700                 705

 Ser Met Val Cys Pro His Met Thr Trp Arg Ala Lys Ser Ser Ala
                 710                 715                 720

 Lys Gly Lys Pro Arg Ser
                 725

<210> 5125
<211> 837
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 404-623
<223> Unknown base

<400> 5125
 aaaattcttc cttttttgct agatttgttg tcaccaaaat tatctgtttg 50

 gctttaggaa gagggaattt tattagatta tcaagctttg taaaatttat 100

 ttgtacttgg gcaaacctaa gtaagagcat actgcaaagc tactgcttgg 150

 atgtagaggg ctaaattgta ggtacttctg aaacttttta tagatactga 200

 ctcataagtg taatttgaaa gtaccccttg acccaaacaa aactgcttct 250

 caaaacttct cattttctcc ctgagaagca ttctaaagaa ttgttctctg 300

 ttcatttcta agagaaagat ttactgggtg tatgatgcgg ttacttttaa 350

 gttatttcta ctggccagtt ggagcaatat atattaaagg tcttgcatac 400

 agtnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 450

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 600

 nnnnnnnnnn nnnnnnnnnn nnntttggtt tagtctacaa ctataccttc 650

 cttataactt aaccatatgc atttattagg aaaagtttat gtaatgcaga 700

 caggaagctc tatgttccct tctctggggc atcctgaacg tctgaagggt 750

 cacagatgtc tgtgtagaga tctgtaagat gtcaaagaat aaagataatt 800

 tatagactaa gctataactc atgtgccttt actattt 837

<210> 5126
<211> 115
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 25-98
<223> unknown amino acid

<220>
<221> Unsure
<222> 404-623
<223> Unknown amino acid

<400> 5126
 Met Met Arg Leu Leu Leu Ser Tyr Phe Tyr Trp Pro Val Gly Ala
   1               5                  10                  15

 Ile Tyr Ile Lys Gly Leu Ala Tyr Ser Xaa Xaa Xaa Xaa Xaa Xaa
                  20                  25                  30

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  35                  40                  45

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  50                  55                  60

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  65                  70                  75

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
                  80                  85                  90

 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Trp Phe Ser Leu Gln Leu Tyr
                  95                 100                 105

 Leu Pro Tyr Asn Leu Thr Ile Cys Ile Tyr
                 110                 115

<210> 5127
<211> 2343
<212> DNA
<213> Homo sapien

<400> 5127
 agagagatag ctcccatgat ggaaaggagg atggagtgcg gtgccgtcat 50

 catgaatgga tgtatttatg tcactggagg atactcctac tcaaagggaa 100

 cgtatcttca gagcattgag aaatatgatc cagatcttaa taagtgggaa 150

 atagtgggta atcttcccag tgccatgcgg tctcatgggt gtgtttgtgt 200

 gtataatgtc taattgaatc tgcagaaatg accaagcaat cacttttttg 250

 gagtatagtt ttataaaaaa aagaatgcag ggtttgaagt tccttacctg 300

 ataattgtgt ctggcacatg ataggggatc agtaaattgt aattcctaac 350

 cctactgtac tcccaaacat ggtgattcat ggtcaagaaa aatcttatgt 400

 atatgtatgt atatacacat atatatgtgt tcatatgtat gcgttcatac 450

 atacgcgcgt atgtatacat atatgtgtat acatacgtgt gtatgtatac 500

 atatatgtgt atacatacgt gtgtatgtat acatatatgt gtatacatat 550

 atatgtgtgt atatatatac acatatatac gtatatatgt gtatatatat 600

 acacagttga atcagtggga ttaataccta taatctctgg ttttcaaagg 650

 taatatggaa tatttgacac ttggtaaaag gtgaactacc tttgtagtga 700

 atcttttcct cttggtagca tcaacactgg ggataaatca gaaccattct 750

 gtggaatgaa atgtttctca agagcctata atatagtaga tagtgcatat 800

 taagatgtct ggctgggcat ggtggctcat gcctgtaatc ccagcacttt 850

 gggaggctga ggcgggagga tcacttgagc ctagaagttg gagactaacc 900

 tggcgagacc ctgtctcaaa aaaaaaaaaa aaatcaattt agctagcagg 950

 aatttgacat ttaaagaggg aatcttctct acctctacaa aatcaacact 1000

 taacactttt ttcaccttca gaattattta gaatgtggat ttactttgtc 1050

 tagttttttc ctttatagtg taatttattg ttactctcta tttactgact 1100

 accagagata tacaaaatac tgtgcaaaag attgttactg ttcaaagagc 1150

 ttacaaacta aatttaaaag aatagcaagt ctgaaaaata gaagatagtc 1200

 aaatatttgt ttatgccaag aactgttttt aattttcagc tttgatgtaa 1250

 attgctagct taggtgtctt tagttcaagc atgttaggaa atcctcttta 1300

 ttcttaaata tagatacatg tctgcatata tgattgaatt ttagagccag 1350

 aaagcatgta gagcagttgt gattagtaga aaatacactg acaagaagat 1400

 atttgcattt atttcccaaa gctgccagta actagatttt gtgacttaag 1450

 tcatttaacc tctccttgat tagagcttcc tgagccatgc acactggcac 1500

 tgcaaatcac agacaggcct agatacagat cccctcaccc cttgctacat 1550

 ccaaaggtgg cctgggtggc tggagcctct gggccagaac cacctttgtc 1600

 cattttcctc agtgtgccta cagcatcgct ttccatgtgt gccataactt 1650

 gggaatagtt gggatgtgtt gcttaactcc tttgcaccat tagttatctg 1700

 tgagaccatc tattccacac tcttcatttt ttaaaaagag acaataatta 1750

 tttttaactc actgaagttt aaaactacct agcatttctg attaaaaaaa 1800

 atttagaagg aaaattttaa tgcatttatt tcagatggcg ttttaaatag 1850

 atacaaccct ttggaaacac aatatggtac tacatagcaa gggctgtaaa 1900

 aatgaccata tcctttgccc cataaattct acttctatac ttttaacctt 1950

 aaaaataatt cagaaaaaag ataaatgcat gaagacattt atgtctgcat 2000

 tctttataat aacaaaaatt ggggaaaaaa actccatgtc aagaaagtgg 2050

 gataagaaaa atagtgaagt attatactgc cattaaaata attatttgga 2100

 agactgtaga aacgtggaca tgtttgatat ggtaagtaaa atgagcacaa 2150

 tacaaaatag tatgcatact atgattgtga ctttgtaaaa tctttatgca 2200

 tgtggaaggt aatctgcaaa acaaattcat tgtgttagtg tagcgggata 2250

 tggaatgact ttatttattt aaatcttttc tttaatatta ctttgtattt 2300

 tcaataaaaa taaatcactg taaaaaaaaa aaaaaaaaaa aaa 2343

<210> 5128
<211> 75
<212> PRT
<213> Homo sapien

<400> 5128
 Met Tyr Met Tyr Val Tyr Thr His Ile Tyr Val Phe Ile Cys Met
   1               5                  10                  15

 Arg Ser Tyr Ile Arg Ala Tyr Val Tyr Ile Tyr Val Tyr Thr Tyr
                  20                  25                  30

 Val Cys Met Tyr Thr Tyr Met Cys Ile His Thr Cys Val Cys Ile
                  35                  40                  45

 His Ile Cys Val Tyr Ile Tyr Met Cys Val Tyr Ile Tyr Thr Tyr
                  50                  55                  60

 Ile Arg Ile Tyr Val Tyr Ile Tyr Thr Gln Leu Asn Gln Trp Asp
                  65                  70                  75

<210> 5129
<211> 1007
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 905
<223> Unknown base

<400> 5129
 aaaaccaagt tgtcttggaa caaagatggc attctccatg gagtcagata 50

 tcaggatggg aatctggtga tccaattccc tgattactgt ggcatgatcc 100

 tccaccattc acactctacc ctggactctg ggaagggaca ctgctgcctt 150

 gaaactctac aaccctgaac cttgatgctg gttgctgcag acaagaactg 200

 cttctaccct gggtcactgt cactgctaag tggaaagtca tgaacttgat 250

 ggtaccagtc actctgggcc taaaccgaca tagccaggaa acggttcacc 300

 ccccacaaac agaatcatct agacctgtcc atgatttgga atcgtggccc 350

 aatacttcct ggccccagag agagaaaaaa gtctgaccac cccctactca 400

 aagtgccaac tcatttcctt cccagaatta atcacttccc aaaatgtatg 450

 actgtgtgaa catcaattcc cttcagggga aaaccccact cccacctctc 500

 aggctgtcat cttaccctat gaccccaacc tgacaatcat gcaacagccc 550

 attattggta ccttttccaa tgtttaggtg actcattctt atctacaatc 600

 actttgttgt tctaggaaag tttttgacac agcaggcatt tgatatatat 650

 ttcttgatta aatgaaagat taaatgaata ccatcttaga tgtctgcata 700

 gtgctttaaa gtttacacca ctattctttc aaatagtaca agagagaact 750

 aagctgtgta ctcaactggg aagaagcaga actgagagtg ggagcacctg 800

 gtattctgat ttcttgtcta gaactatact atattctgag atcactaaac 850

 tacaacctca ggcgactctg cctacttttg taaagaaagt tgtattggaa 900

 cacanctgcg cccatcggcc tgtgcactgc aatggcagtg gtgaagcatg 950

 gccttcagag cctcaaatag ttactatctg actctttata gaaagtttgc 1000

 tgactcc 1007

<210> 5130
<211> 55
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 905
<223> Unknown amino acid

<400> 5130
 Lys Thr Lys Leu Ser Trp Asn Lys Asp Gly Ile Leu His Gly Val
   1               5                  10                  15

 Arg Tyr Gln Asp Gly Asn Leu Val Ile Gln Phe Pro Asp Tyr Cys
                  20                  25                  30

 Gly Met Ile Leu His His Ser His Ser Thr Leu Asp Ser Gly Lys
                  35                  40                  45

 Gly His Cys Cys Leu Glu Thr Leu Gln Pro
                  50                  55

<210> 5131
<211> 903
<212> DNA
<213> Homo sapien

<400> 5131
 gtgtattatg cctccatgac attgttacat tctatgagga gcatctgtct 50

 cctttctaga cttgaactgt ggtagaaaaa gcccccttct ctcttctatc 100

 tacttagatt tggtgatgct aggaatgtag tgttttagat attaattcta 150

 tttttattta ttcattttta catcaccaat aggatctgag gtggagatgg 200

 cgggtattat cactggcatt ttacaggtga gaaagcccaa agccactgag 250

 gtaattaatg gaataattga ttttgaactt gggtctgtct gatttcatgt 300

 gcaagattat atacttagtg attttgattt taagtttatt cttaacattt 350

 taaaccagac tattaactct tacctttata accacagata caaagaactg 400

 tatcatttat tttctgaata taaaatatta atggtcaata taaaaataca 450

 aaaatagaga actatataca acagaaaagc aaaattaccc actaataaca 500

 ctttgattta tatcccttta gacactgttt agagtttata catatatgta 550

 aatatgcttg tattttaaca aaattgagat attatataaa ctgtttgtag 600

 cagggtgttt aaaattttaa caatatgtta tggatatctt tctgtgtcaa 650

 taaatgtgta tttacattag agttccaagc atttgaactg aatctagtcc 700

 aaaaatgatg tgttttattt ggccagggga cattttttaa aaaaatcttt 750

 aagcaataga cagcttttga aattcagaaa atgttacgta caattcaatg 800

 tcctgcatgt tttaaaatac tggataatct aacaacacag aacacctccc 850

 actccccacc tcacaaccac cacacatata ctttcttgct tggcatcagt 900

 taa 903

<210> 5132
<211> 40
<212> PRT
<213> Homo sapien

<400> 5132
 Met Leu Arg Thr Ile Gln Cys Pro Ala Cys Phe Lys Ile Leu Asp
   1               5                  10                  15

 Asn Leu Thr Thr Gln Asn Thr Ser His Ser Pro Pro His Asn His
                  20                  25                  30

 His Thr Tyr Thr Phe Leu Leu Gly Ile Ser
                  35                  40

<210> 5133
<211> 2582
<212> DNA
<213> Homo sapien

<400> 5133
 attcaccaag gctaacatgg tggccacctc tactgctgtc atctctggag 50

 tgatgagcct cctgggttta gcccttgccc cagcaacagg aggaggaagc 100

 ctgctgctct ccaccgctgg tcaaggtttg gcaacagcag ctggggtcac 150

 cagcatcgtg agtggtacgt tggaacgctc caaaaataaa gaagcccaag 200

 cacgggcgga agacatactg cccacctacg accaagagga cagggaggat 250

 gaggaagaga aggcagacta tgtcacagct gctggaaaga ttatctataa 300

 tcttagaaac accttgaagt atgccaagaa aaacgtccgt gcattttgga 350

 aactcagagc caacccacgc ttggccaatg ctaccaagcg tcttctgacc 400

 actggccaag tctcctcccg gagccgcgtg caggtgcaaa aggcctttgc 450

 gggaacaaca ctggcgatga ccaaaaatgc tcgcgtgctg ggaggtgtga 500

 tgtccgcctt ctcccttggc tatgacttgg ccactctctc aaaggaatgg 550

 aagcacctga aggaaggagc aaggacaaag tttgcggaag agttgagagc 600

 caaggccttg gagctggaga ggaaactcac agaactcacc cagctctaca 650

 agagcttgca gcagaaagtg aggtcaaggg ccagaggggt ggggaaggat 700

 ttaactggga cctgcgaaac cgaggcttac tggaaggagt taagggagca 750

 tgtgtggatg tggctgtggc tgtgtgtgtg tctgtgtgtc tgtgtgtatg 800

 tacagtttac atgaatgttc ctcaggacat ggcatacaat ggccttggag 850

 gtccaaataa tatcaagtac atcttggaga tgagggtgcc tgtcctggac 900

 agacctcggc atgccttctg tttctccttc aatgctcctt aaggcctatg 950

 tgctgggaaa agggtcttcc ctgtttgttt gtttgtttgt ttgtttgttt 1000

 gtttgtttgt tttgagacgg ggtctctgtt gcccaggctg gagtgcagtg 1050

 gcgtaatctc ggctcactgc aacctctgcc tcctgggtgc aagaaagtct 1100

 cctgcctcag cctcccaagt agctgggatt acaggcacgc accaccacgc 1150

 ccagctaatt ttggtatttt tagtagagac agggtttcac cattttggcc 1200

 aggctggtct cgaattcctg acctcaagtg atccacccac cttggcttcc 1250

 caaaatgctg ggattacaag cgtgagctac cctgcccagc cgggtcttcc 1300

 cagttttaac aaagaggtca ctgagccaca ggcggagtta ggaactaaat 1350

 tgtctcctcc tcccaattca tatgttgaag tcctaaacca aaatgtggct 1400

 gtatttagag atggaccctt tgggaggtaa ttagggttga ctgaggccat 1450

 agggtgaggt cctaacccga tggaattgac ttctttataa gaggaggagg 1500

 aaatacaaga gggcctcccc acccctgctg cacacctaca ctgaaggaag 1550

 gctatttgca gatgcagcaa gaaggcagcc atctgcaagg cagaagaaga 1600

 gagccctcac caggaactga ataagtcagt cagtctggga cttccagcct 1650

 ctagaactgt gaaacaataa atttctgtgg tgtaagcaac tcaatctata 1700

 gtagtttgtt actattttgt tatagcaacc aaagatgact aagccagaca 1750

 ggttatgtca ctcgccaagt gtcttagtct gtttgtgctg ctataacaaa 1800

 ataccttaga ctgggtaatt tacaaacaac agagatgtat ccagagatcc 1850

 acagttctgg aggctgagaa gtctaaaatc aaggcaccag cagattccac 1900

 atctcatgaa ggctcactct ctgcttcaca gatggcactg tcttgctgtg 1950

 ttctcacatg gcagaagggg caaacaagcc cccctgggcc tcttttataa 2000

 aggcactaac tctatgccta aaggcagggc cctcatgact ctatcaccta 2050

 ccaaaaggct ccacttcttt atactattgg aggggtagaa ggaacttcct 2100

 ttctagacct tgaaggttta agaatttgaa tctataaaac aagctgacaa 2150

 tagacagatt aacaggagaa gaagcatata cattttttaa tgtgggccag 2200

 atggcagaag cttaaataac accccaagct acaggaagtg aggcctctga 2250

 tggggaggta gtgacacagg ctgtgggagg gggtaggggg aggaagtctg 2300

 tggtgagcaa agtttgcctt attacactga taaagtgtaa ttacactaat 2350

 aaagctggat cacctgaggt taggagtttg agaacagcct ggccaacatg 2400

 gcaaaaccct gtctctacta taaatacaaa aattagccag gtgtagtggc 2450

 agggcacttg tagtcctatc tactcgggag gctgaagcag gagaatcgct 2500

 tgagcccagg ctgtaaaggt tgcagtgagc caagatcgtg ccactgcact 2550

 ccagtctggg tgtcagaatg agaccccgtc tc 2582

<210> 5134
<211> 265
<212> PRT
<213> Homo sapien

<400> 5134
 Met Val Ala Thr Ser Thr Ala Val Ile Ser Gly Val Met Ser Leu
   1               5                  10                  15

 Leu Gly Leu Ala Leu Ala Pro Ala Thr Gly Gly Gly Ser Leu Leu
                  20                  25                  30

 Leu Ser Thr Ala Gly Gln Gly Leu Ala Thr Ala Ala Gly Val Thr
                  35                  40                  45

 Ser Ile Val Ser Gly Thr Leu Glu Arg Ser Lys Asn Lys Glu Ala
                  50                  55                  60

 Gln Ala Arg Ala Glu Asp Ile Leu Pro Thr Tyr Asp Gln Glu Asp
                  65                  70                  75

 Arg Glu Asp Glu Glu Glu Lys Ala Asp Tyr Val Thr Ala Ala Gly
                  80                  85                  90

 Lys Ile Ile Tyr Asn Leu Arg Asn Thr Leu Lys Tyr Ala Lys Lys
                  95                 100                 105

 Asn Val Arg Ala Phe Trp Lys Leu Arg Ala Asn Pro Arg Leu Ala
                 110                 115                 120

 Asn Ala Thr Lys Arg Leu Leu Thr Thr Gly Gln Val Ser Ser Arg
                 125                 130                 135

 Ser Arg Val Gln Val Gln Lys Ala Phe Ala Gly Thr Thr Leu Ala
                 140                 145                 150

 Met Thr Lys Asn Ala Arg Val Leu Gly Gly Val Met Ser Ala Phe
                 155                 160                 165

 Ser Leu Gly Tyr Asp Leu Ala Thr Leu Ser Lys Glu Trp Lys His
                 170                 175                 180

 Leu Lys Glu Gly Ala Arg Thr Lys Phe Ala Glu Glu Leu Arg Ala
                 185                 190                 195

 Lys Ala Leu Glu Leu Glu Arg Lys Leu Thr Glu Leu Thr Gln Leu
                 200                 205                 210

 Tyr Lys Ser Leu Gln Gln Lys Val Arg Ser Arg Ala Arg Gly Val
                 215                 220                 225

 Gly Lys Asp Leu Thr Gly Thr Cys Glu Thr Glu Ala Tyr Trp Lys
                 230                 235                 240

 Glu Leu Arg Glu His Val Trp Met Trp Leu Trp Leu Cys Val Cys
                 245                 250                 255

 Leu Cys Val Cys Val Tyr Val Gln Phe Thr
                 260                 265

<210> 5135
<211> 1517
<212> DNA
<213> Homo sapien

<400> 5135
 ctgcgcctgg cgtcaccgac cggtgcggac aggaagaggc tctgggctgg 50

 cacatgtgta tggcggtgag gcgggcgggt acatggcggg ctctgtggga 100

 ctggcgttgt gcgggcagac gttggtggtg cggggcggca gccgattcct 150

 ggccacctcc atagcaagca gtgatgatga cagcctcttc atctatgact 200

 gcagtgctgc agaaaagaag tcacaagaaa ataaagggga ggacgcgccc 250

 ttggaccagg ggagcggtgc gattctggcg tccaccttct ccaagtctgg 300

 cagctatttt gctttaaccg atgacagtaa gcgtctgatt cttttccgta 350

 caaaaccatg gcaatgtctg agtgtcagga ccgtggcaag gaggtgtaca 400

 gccctgactt tcatagcctc ggaggagaag gtcttggtgg ccgacaagtc 450

 tggagacgtc tactcctttt cggtgctgga gccacacggg tgtggccgtc 500

 tagagctggg gcacctgtct atgctgttag atgtggctgt gagtcctgat 550

 gaccgcttca tcctcactgc cgaccgggac gagaagatcc gagtcagctg 600

 ggccgcggcg ccccatagca tcgagtcctt ctgcttgggg cacacagagt 650

 ttgtgagccg tatctccgtg gtgccaactc agcccgggct gcttctgtcc 700

 tcctctgggg acggcaccct gaggctctgg gagtacagga gcggccgcca 750

 gctgcactgc tgtcacctgg ccagtctgca ggagctggtg gacccccagg 800

 ccccccagaa gtttgccgcg tccaggattg cattctggtg ccaggagaac 850

 tgcgtggcgc tcctgtgcga cggcactcct gtggtctaca tcttccagct 900

 ggacgcccgc agacagcagt tggtgtacag gcagcagctg gcgttccagc 950

 accaagtgtg ggacgtggct ttcgaggaga cccaggggct gtgggtgctc 1000

 caggactgcc aggaagcccc cctggtgctc tacaggcctg tgggcgacca 1050

 gtggcagtct gttcctgaga gcaccgtgtt aaagaaagtc tctggtgttc 1100

 ttcgtgggaa ctgggccatg ctggaaggct ctgccggcgc agacgccagc 1150

 ttcagcagtc tctacaaggc cacgttcgac aacgtgacct cctacctgaa 1200

 gaagaaagag gagagactgc agcagcagct agagaagaag cagcggcgcc 1250

 ggagtccccc gcctgggccc gacgggcatg ccaagaagat gagaccgggg 1300

 gaggcgacgc taagttgctg atcgtggcgg tctgtttctg tcgactgtgg 1350

 accacttatg tgcgatccgt ggaccacttg cgtgcgatct gtcggccgac 1400

 gatgagcttg ttcggatgta gctccatcgt aagtcgagga gcatctgtga 1450

 tttgtcctct gcttatggga tatgtttttc cgctactgag tctgtgtagt 1500

 aaatttttga ctaggaa 1517

<210> 5136
<211> 412
<212> PRT
<213> Homo sapien

<400> 5136
 Met Ala Gly Ser Val Gly Leu Ala Leu Cys Gly Gln Thr Leu Val
   1               5                  10                  15

 Val Arg Gly Gly Ser Arg Phe Leu Ala Thr Ser Ile Ala Ser Ser
                  20                  25                  30

 Asp Asp Asp Ser Leu Phe Ile Tyr Asp Cys Ser Ala Ala Glu Lys
                  35                  40                  45

 Lys Ser Gln Glu Asn Lys Gly Glu Asp Ala Pro Leu Asp Gln Gly
                  50                  55                  60

 Ser Gly Ala Ile Leu Ala Ser Thr Phe Ser Lys Ser Gly Ser Tyr
                  65                  70                  75

 Phe Ala Leu Thr Asp Asp Ser Lys Arg Leu Ile Leu Phe Arg Thr
                  80                  85                  90

 Lys Pro Trp Gln Cys Leu Ser Val Arg Thr Val Ala Arg Arg Cys
                  95                 100                 105

 Thr Ala Leu Thr Phe Ile Ala Ser Glu Glu Lys Val Leu Val Ala
                 110                 115                 120

 Asp Lys Ser Gly Asp Val Tyr Ser Phe Ser Val Leu Glu Pro His
                 125                 130                 135

 Gly Cys Gly Arg Leu Glu Leu Gly His Leu Ser Met Leu Leu Asp
                 140                 145                 150

 Val Ala Val Ser Pro Asp Asp Arg Phe Ile Leu Thr Ala Asp Arg
                 155                 160                 165

 Asp Glu Lys Ile Arg Val Ser Trp Ala Ala Ala Pro His Ser Ile
                 170                 175                 180

 Glu Ser Phe Cys Leu Gly His Thr Glu Phe Val Ser Arg Ile Ser
                 185                 190                 195

 Val Val Pro Thr Gln Pro Gly Leu Leu Leu Ser Ser Ser Gly Asp
                 200                 205                 210

 Gly Thr Leu Arg Leu Trp Glu Tyr Arg Ser Gly Arg Gln Leu His
                 215                 220                 225

 Cys Cys His Leu Ala Ser Leu Gln Glu Leu Val Asp Pro Gln Ala
                 230                 235                 240

 Pro Gln Lys Phe Ala Ala Ser Arg Ile Ala Phe Trp Cys Gln Glu
                 245                 250                 255

 Asn Cys Val Ala Leu Leu Cys Asp Gly Thr Pro Val Val Tyr Ile
                 260                 265                 270

 Phe Gln Leu Asp Ala Arg Arg Gln Gln Leu Val Tyr Arg Gln Gln
                 275                 280                 285

 Leu Ala Phe Gln His Gln Val Trp Asp Val Ala Phe Glu Glu Thr
                 290                 295                 300

 Gln Gly Leu Trp Val Leu Gln Asp Cys Gln Glu Ala Pro Leu Val
                 305                 310                 315

 Leu Tyr Arg Pro Val Gly Asp Gln Trp Gln Ser Val Pro Glu Ser
                 320                 325                 330

 Thr Val Leu Lys Lys Val Ser Gly Val Leu Arg Gly Asn Trp Ala
                 335                 340                 345

 Met Leu Glu Gly Ser Ala Gly Ala Asp Ala Ser Phe Ser Ser Leu
                 350                 355                 360

 Tyr Lys Ala Thr Phe Asp Asn Val Thr Ser Tyr Leu Lys Lys Lys
                 365                 370                 375

 Glu Glu Arg Leu Gln Gln Gln Leu Glu Lys Lys Gln Arg Arg Arg
                 380                 385                 390

 Ser Pro Pro Pro Gly Pro Asp Gly His Ala Lys Lys Met Arg Pro
                 395                 400                 405

 Gly Glu Ala Thr Leu Ser Cys
                 410

<210> 5137
<211> 510
<212> DNA
<213> Homo sapien

<400> 5137
 atttcttaac ttgattactc tttcttcact tgaccagaga gtccagaagg 50

 gcaggttcta tgtctggttt tgcacaccaa ttataaagct tcatttatgc 100

 atttcaaact tgaatagtaa gacgaaaatc tttatatttt cttatgagtc 150

 tccataaaac ctagcgttta ctcattctta actcattctt tgtagcatca 200

 taacattgta gactttgtat aaaataagta agatactctt tgtatatgcc 250

 taagtcaaga tctaaaatat tatatggtac tacaatgtca cttaacattt 300

 ctcactttct gcctttccat ttggttattt aattttataa ccatcccaaa 350

 tcacagaaca actgtatcta tcctacatta tatataagaa aaccttgtag 400

 aagagttgaa acccaggata tcaccacata tcaaagaccc aaccaaaggc 450

 tgaggaatac tgctttgcag tacaatcgat gttatcaata tttgtttgta 500

 tttgtcgacc 510

<210> 5138
<211> 51
<212> PRT
<213> Homo sapien

<400> 5138
 Phe Leu Asn Leu Ile Thr Leu Ser Ser Leu Asp Gln Arg Val Gln
   1               5                  10                  15

 Lys Gly Arg Phe Tyr Val Trp Phe Cys Thr Pro Ile Ile Lys Leu
                  20                  25                  30

 His Leu Cys Ile Ser Asn Leu Asn Ser Lys Thr Lys Ile Phe Ile
                  35                  40                  45

 Phe Ser Tyr Glu Ser Pro
                  50

<210> 5139
<211> 594
<212> DNA
<213> Homo sapien

<400> 5139
 taactcacac agagccagct gtgcaggaga ccagagtttt atttatattt 50

 atagatataa attcataaga gtttaattag ctctcaggct cacttcaggt 100

 acatttcatg actccaactc ctgttgtaca aaatatccct gcttttaaac 150

 agtagattta aaacaaacaa ccttggtttt ctgggacttt tcttttatga 200

 gtattttttt attaatgtaa agtttcaaag aaggctaatc aaacacaaaa 250

 atatctgcaa agagccacaa taagccttga acaacataca gtcagtaaaa 300

 catcaaggtt taaattgttg ctttaacttc cttttggctg gaagctccat 350

 attctggtaa ttcaccaaaa tggccaacac aaggaaaaca ggagaggcac 400

 ccagtgtatg ttttctaggc cttttagaaa acatggagtt ggccacatgc 450

 atgggagtct ataaaaaagg tgatactgta gacatcaagg gaatgggtat 500

 ggttcaaaaa ggaatgcctc acaagtgtta ccatggcaaa aactggaaga 550

 gtctataatg ttactcagca tgctgttagc attgctgtag ggaa 594

<210> 5140
<211> 62
<212> PRT
<213> Homo sapien

<400> 5140
 Met Ala Asn Thr Arg Lys Thr Gly Glu Ala Pro Ser Val Cys Phe
   1               5                  10                  15

 Leu Gly Leu Leu Glu Asn Met Glu Leu Ala Thr Cys Met Gly Val
                  20                  25                  30

 Tyr Lys Lys Gly Asp Thr Val Asp Ile Lys Gly Met Gly Met Val
                  35                  40                  45

 Gln Lys Gly Met Pro His Lys Cys Tyr His Gly Lys Asn Trp Lys
                  50                  55                  60

 Ser Leu


<210> 5141
<211> 1187
<212> DNA
<213> Homo sapien

<400> 5141
 gggaaataaa aacatgtagc tttgtataca tttggcttct aaaacaatta 50

 tcaaaggggt catagtaaaa ggatatataa aggtaacaat tatacttttg 100

 actgagcgtc tctgcttttt ttttttttta actgcaacta atttctagac 150

 tgttacttat tgaaatggag atctttttgg accctgcctt catcagctct 200

 gtgtaaactt tatggggaaa aaagcactgg gtgtatagat aatgtcttta 250

 aaggtacggg gtggtgagtg ggatttcctt cagatagaaa tatttctcat 300

 aggttaacca ttcccctata gtatagttgt tgtgtcttgt acctgagctg 350

 gtaatccaga attatttgta tttctgtgct gcctgcacaa aaaatcatga 400

 agtgagttaa gtagtttgtg ccacccagga gttgcacctt ttctcaggtt 450

 ccactagatg gtatgacagt ggaattagcc ccaggcagtg tctaaaatcc 500

 cacttctgtt gctgaccctg tggcctcaga aaagggtcct ttttgctttg 550

 tttcctcttt atcagggtgt tggaagaagg atctctaagt gtctctctgt 600

 gatcctctga gcaaggaggt agataaaatt gttagcttat ttaattttca 650

 cttttactaa gactctattt ttattttagc cgtataggtg agggacttga 700

 tcaggctctg ccctgtctga cagaactcat tctcaccaat aatagtctcg 750

 tggaactggt aagttgcaca gaaggaaaat gtatttggtg ggtggggtta 800

 aaggtactat gtgcttccta cagaaaattt acaaaatcta gaaaatgatc 850

 tcagtatcct ctttcttgtc tttttcttaa ttcaggatct gggccttttg 900

 ggttctgcag ccgtatgttg caaatatttt cctactttta cttgactttt 950

 gacttaggat gtcttgttag agaagttcct aatttaggtg cagtccaatg 1000

 aatcaatctt cttctttatt gtagcccttt tgatgtttaa atttccccta 1050

 ttccagggtt ataaactcct atgttgtttt ctacaattgc agtgttcaat 1100

 atagtaccag taactacagg tggctactta taattgagat gtgctagaac 1150

 tattaaattc acaattgaat ttcaaagact taagtgc 1187

<210> 5142
<211> 20
<212> PRT
<213> Homo sapien

<400> 5142
 Glu Ile Lys Thr Cys Ser Phe Val Tyr Ile Trp Leu Leu Lys Gln
   1               5                  10                  15

 Leu Ser Lys Gly Ser
                  20

<210> 5143
<211> 1119
<212> DNA
<213> Homo sapien

<400> 5143
 tcgctgcctg tttgtgcacg cttaaggagg gttggtcgaa tgaatgaatt 50

 cagtctgtat cctcaacacc caatgccgcg cctggcacca taggcgttca 100

 catgcagccg tgccgaaaga ctgagtgaat gctggactga atgaatgact 150

 gcctgtaaaa tatctacagg aaagccctgc aggaaatgcc ctccataaat 200

 tctagtcccc ttctccttcc taaccaaatc ctcccctcct tctgcttcca 250

 tcacttccta gctgtgtaac ttaggcaaag tggtttacct ctctgtgtct 300

 aatttcggca aaggtaaaat ggggaagtga acctcatctg gttctggtga 350

 gcttccacgg gtgctgtatg gaaagcctgg caccctgcct ggtggagagg 400

 gctcgatgat ggttagaagg agagtttctc taaactgccg cctaccttcc 450

 ttcccctttc tcatttcctg ccacaagtct cccacccact ttctctgtct 500

 ccctctcacc ccttgtcttt ctccatcttg tcttcccgta aagacccagc 550

 ccttccctcc tccatgaaac ctggattcct ccaaggcgaa ggcccccctc 600

 tctggggtct cagcctccag cgctgacatc ctaggccgcc tcgacaggtg 650

 ggctcaccat ccaacccttc ctcctccccc ttcagccccc tcctcctgct 700

 cttcaactga ggttcgcctt cccagctccc ccacgccctg cacagtgctg 750

 atcagtaaaa gaggaggaca ctgacgagtg gcgacttggt tcacggggtt 800

 ctttgcttcc tcggtggcgg aggggcctgg ggcctctctc cagcacctct 850

 gcccttccgc agccatcgag ttgatcaaag acctggtcgg ttacgatgtg 900

 cgccaggcgc tgctcaaggg cctcgtggcg ctgctgatac cgtcggtcaa 950

 ggagatctcc aaactgcagg ccaagatcct cagtggtaag gacctgctca 1000

 aatggggctg cctgggccac gggagggcgg ctcttgcctc acggctgccc 1050

 cctcctcaga cccctcggtt ctccagctca cccccagcct gccgatgttt 1100

 ttgcagcagc cgcggccgc 1119

<210> 5144
<211> 39
<212> PRT
<213> Homo sapien

<400> 5144
 Met Gly Leu Pro Gly Pro Arg Glu Gly Gly Ser Cys Leu Thr Ala
   1               5                  10                  15

 Ala Pro Ser Ser Asp Pro Ser Val Leu Gln Leu Thr Pro Ser Leu
                  20                  25                  30

 Pro Met Phe Leu Gln Gln Pro Arg Pro
                  35

<210> 5145
<211> 5344
<212> DNA
<213> Homo sapien

<400> 5145
 cgcctgggcg cggcggaggg cggggagccg ggcaggtcgc gcctgcgggc 50

 ggcagccgac cgccgggagc tgttctgatt tccgacgcgc acgctagggg 100

 cccggagcag cccccggccc cggcgcgccg ccgacatggg caacgcaggg 150

 agcatggatt cgcagcagac cgatttcagg gcgcacaacg tgcctttgaa 200

 gctgccgatg ccagagccag gtgaactgga ggagcgattt gccatcgtgc 250

 tgaacgctat gaacctacct cctgacaaag ccaggttact gcggcagtat 300

 gataatgaga aaaaatggga actgatttgt gatcaggaac gattccaggt 350

 gaagaatcct ccccatacat acattcaaaa gctcaaaggc tatctggatc 400

 cagctgtaac caggaagaaa ttcagacggc gtgttcaaga atctacacaa 450

 gtgctaagag aactggaaat ttctttaaga actaaccaca ttggatgggt 500

 cagagaattt ctgaatgaag aaaacaaagg tcttgatgtt ctagtggaat 550

 atctctcatt tgcacagtac gcggtaactt ttgactttga aagtgtggag 600

 agtactgtgg agagctcggt ggacaaatca aagccctgga gtaggtccat 650

 cgaggacctg cacagaggga gcaacctgcc ctcacctgtg ggcaacagtg 700

 tctcccgctc tggaagacat tctgcactgc gatataatac attgccaagc 750

 agaagaactc tgaaaaattc aagattagtg agtaagaaag atgatgtgca 800

 tgtctgtatc atgtgtttac gtgccatcat gaattatcag tatggtttca 850

 acatggtcat gtctcatcca cacgctgtca atgagattgc actaagcctg 900

 aacaacaaga atcccagaac aaaagccctt gtcttagaac tgttggcagc 950

 cgtttgtctt gtcagaggcg ggcatgaaat cattttatca gcatttgata 1000

 actttaaaga ggtttgtgga gaaaaacagc gctttgagaa gttgatggaa 1050

 catttcagga atgaagacaa taacatagat tttatggtgg cttctatgca 1100

 gtttattaat attgtagtcc attcagtaga agatatgaat ttcagagttc 1150

 acctgcagta tgaatttacc aaattaggcc tggacgaata cttggacaag 1200

 ctgaaacaca ctgagagtga caagcttcaa gtccagatcc aggcttacct 1250

 ggacaatgtt tttgatgtag gagctctact ggaagatgct gaaactaaga 1300

 atgctgcctt ggagagggtg gaagaactgg aagaaaacat ttctcattta 1350

 tctgaaaaac tgcaagacac agagaatgaa gccatgtcca agattgtgga 1400

 actggaaaag caactcatgc agaggaacaa ggagctggat gtcgttcggg 1450

 aaatctacaa agatgcaaat actcaagttc acacattaag aaaaatggtc 1500

 aaagaaaaag aagaagcaat tcaaagacag tctaccctgg aaaaaaagat 1550

 tcatgagcta gagaaacaag ggaccattaa aattcagaag aaaggggatg 1600

 gggatatcgc catactgcca gttgtggctt ctggcacatt gtccatgggg 1650

 tcagaagtgg tagcaggtaa ctctgtggga cccacaatgg gggccgcttc 1700

 ctcaggaccc ttgccccctc ctccaccacc actgcctccc tcatcagaca 1750

 cacctgaaac agtgcaaaat ggtccagtaa caccacctat gccaccgccg 1800

 ccgccgccac cccctcctcc acctcctcct cccccaccgc cccctccccc 1850

 tcctcctctc ccaggccctg catctgagac tgtaccagct cctcccttag 1900

 cacctcccct tccctctgca cctccgctgc ctggaacatc ttcacccaca 1950

 gtggttttca actcaggatt agcagctgtg aaaattaaga agccaatcaa 2000

 gacgaagttc agaatgccag tgtttaactg ggttgctctg aagcccaatc 2050

 agatcaatgg cacagtcttc aatgaaattg atgatgagcg aattctggag 2100

 gatttaaatg tggatgaatt tgaggaaata ttcaagacaa aagcccaagg 2150

 acctgccatt gatctttctt caagcaaaca gaagatacca cagaagggat 2200

 caaacaaagt gacattacta gaagcaaaca gggccaaaaa tcttgccata 2250

 actttaagga aagctggaaa gactgctgat gaaatatgta aagctattca 2300

 tgtatttgac ttgaagacac tgcctgtgga ctttgtggaa tgcttgatgc 2350

 ggttcctacc aactgagaat gaagtgaaag tgcttcggct ctacgagcgg 2400

 gaaaggaagc ctctggaaaa cttgtcagat gaagatcggt tcatgatgca 2450

 gtttagtaaa atcgagaggc tcatgcagaa gatgaccatc atggccttca 2500

 ttgggaactt tgctgaaagc attcagatgc tgactcctca actacatgcg 2550

 attatagcag catctgtctc tataaagtcg tcccaaaaac tcaagaaaat 2600

 tctggagatc atcttagccc ttggaaacta catgaatagc agtaaaagag 2650

 gagcagttta tggatttaaa cttcagagtt tagatctgct cttagataca 2700

 aagtcaacag acagaaagca aacactgttg cactatatat ccaatgtggt 2750

 gaaagaaaaa tatcaccaag tgtccctgtt ttataatgag cttcattatg 2800

 tggaaaaagc tgctgcagtc tcccttgaga atgttttgct ggatgtcaag 2850

 gagctccaga ggggaatgga cttgaccaag agagagtaca ccatgcatga 2900

 ccataacacg ctgctgaagg agttcatcct caacaatgag gggaagctga 2950

 agaagctgca ggatgatgcc aagatcgcac aggatgcctt tgatgatgtt 3000

 gtgaagtatt ttggagaaaa ccccaagaca acaccaccct ctgtcttctt 3050

 tcctgtcttt gtccggtttg tgaaagcata taagcaagca gaagaggaaa 3100

 atgagctgag gaaaaagcag gaacaagctc tcatggaaaa actcctagag 3150

 caagaagctc tgatggagca gcaggatcca aagtctcctt ctcataaatc 3200

 aaagaggcag cagcaagagt taattgcaga attaagaaga cgacaagtta 3250

 aagataacag acatgtatat gagggaaaag atggtgccat tgaagatatt 3300

 atcacagatc ttagaaacca accatacaga cgagccgatg cggtgaggag 3350

 aagcgtcagg cggcgctttg atgatcagaa cttgcgttct gttaatggtg 3400

 ccgaaataac aatgtgaacc tgagactggc ctgcatgaat acagggtgtg 3450

 cgtgaatgaa actgcccaca tgaactttat gtgctacgat ttaactgcag 3500

 ccttgaacac acacaaaaat attcttaagg gctcagattt agcaaacacg 3550

 gaagaatttt aaaatgagct ctcctttcaa cccttgttaa caagtgccta 3600

 aaaatggaag tacctgttca gattaatcaa agcaatagga tttgatttga 3650

 ttaggtatct ttttacacca gtatgttatt tttaaccaaa atgtaaagtt 3700

 cttattaaac tcattacctg ccattgtgat tgtcccatca tggcccacct 3750

 ggtttcctga tgttgtaaat aacatcaatg catctgctgt gggtcctttg 3800

 ctgagatgtc ttcgaaggaa ttttgtttta gccatatcca tcaactttgt 3850

 attttacttg caatttggaa gaaggaaagt cacatgatga aactcctttt 3900

 gtctataacc aggccctggc aaagtgcaaa caggatgcaa ctgcagtggc 3950

 acaaaggtca ctcaatcctt tgtttccagt ttcacattct actacttctg 4000

 cgctagagaa cgatgctctg tgagaggcat tcactagtat gaatgtgggg 4050

 atatagtgta taagacttat ttgcagtact gtgttcttca gctagaggca 4100

 gctttttaaa taatgcaagt gtatttatta gcattaaaat taacatctca 4150

 gtaatcagca ttagcatttc tgaggaccat tattaattct gagaacagaa 4200

 attggtgcct tgcaaggaag tttactagct ctatcaacaa gcattcaagg 4250

 ttacatctgc tagcagagta gtgttaggaa cctggcctta ctctcctctg 4300

 acaatcgcaa ttttttctta ttttttataa attcaagaag atacacttgg 4350

 catcgtgtat cgaggctaag tttttcatgc atttcccaga ctacttatgg 4400

 agaattgcag tttaagttgc tgaaaagtat taacatggta ttaagcttaa 4450

 ataatacgta atgggactag atggcccact aagccactgt tattttcctt 4500

 cctctctggc agggcacttg atccattcca aagtcaaaaa ctggactgaa 4550

 gctaaatttg tacttttcat aatatacatt ctgcttctgg cttatcttct 4600

 tggtacatca atatattaat tgtaaagttt attgtatagt atttaaccgc 4650

 tgaagttcct attttatgtt gtgcttatgt gaaccccttg gtgaaggtcc 4700

 cttttccttg gatgtgtagt tatatgatct ttttaaatgt acagatattt 4750

 tgctataaaa tcggtgcagt tttttatggt ttttacactt ctctttaatt 4800

 cccacctaag cctctgggta atattgtaaa tattgtttta aaatgcatca 4850

 gcctatgcta tacaatctga atgttatttt aacttatagt tttttttaat 4900

 atatatattt aactataagg acagtttagg gaacaagtta cctaccacat 4950

 ttcactttag tgtacctatt tacagaaaga ttaaactgcc acctgcgggc 5000

 acattcccat aaatgtgtac tttactttaa aaagaacatg ccacgatttt 5050

 gtctttctgt ggactcaaca ttcacttcga ttaaaaatag caatttgacc 5100

 aagttggact tccactacaa agcagctgtt ttccaaagtt caatgctgac 5150

 atatatgtat attaaaataa ttgcctattt attaatctac aaatagacaa 5200

 cgttggcatg ttcttttctg tttgtctatt aatgggcctg cttcttagca 5250

 atattagaat gttttataaa agcaattcat gttacttttc tggtcttttc 5300

 atggcatatg agcaaataat aaactattta cactactatt ctgt 5344

<210> 5146
<211> 934
<212> DNA
<213> Homo sapien

<400> 5146
 gtgagagggg ctttcacaag ataacattgt agaatcattc agtgagaaca 50

 aaagttgact caagaaagca agagtctgga tttaaatccc tggtaaaatt 100

 gccttagtaa gcaataataa aatttcccag cacatgactg gggtaagtaa 150

 tgaattgttg aaacctgcaa agagccctaa attataagaa ttatggggga 200

 tcggaggagg aaaataaatg aaaacagaag accataaaag aatactttgc 250

 attcagtaga aaacctgtca gtactgtagg acaaaaagga atagattcta 300

 cattttacat caccagtgat gcctcctcat ggtttaacca tttcttccac 350

 attctgccta aagggaaaac tgtgtcagca attgcttttg gtttttaaag 400

 ttataggttg ctactacatg gatgtgacta agaaaataca tagattatct 450

 taaaatgggc atgatgtaaa agactcaatc agtagggtaa ctaaaaactt 500

 tgtagtactc tagctttgga aatctgagag gcctatatag ttcatttgag 550

 tgtttgatca aattcttatt gagattacag cctgtgcaaa atatttgtga 600

 tgcattttta agtttactta agtacacttt gaaattcttt aaaaatttta 650

 aaatctttaa aaggacacaa gagtgtacca cattgagatt aaaatgtgtt 700

 tattattaat ttgtacataa tactataaca aataattgtt ctcaggtatg 750

 tttaaggcct tattttaaaa gttgattctt caatttctaa tttaaaataa 800

 gcttttagtt tttctcaact atgtatatgt aatgattata aatgcctaga 850

 gtagtgtttc ccagacaact agaaccacac acaaattagt accaccaaaa 900

 aaagtcgacg cggccgctaa tttagtagta gtag 934

<210> 5147
<211> 9
<212> PRT
<213> Homo sapien

<400> 5147
 Glu Arg Gly Phe His Lys Ile Thr Leu
   1               5

<210> 5148
<211> 4616
<212> DNA
<213> Homo sapien

<400> 5148
 gctgttggct gggctcggga gggaacgctc caggtaaagc gctgggggag 50

 gaagcgacgc cgaggagcta cggtttcctc cagaggtctc cgcccctctg 100

 cccctatatt cccagagctc gagtctgatc cgggccttgc cgggcaccct 150

 ggaaaggcgg gggtgatagt acagatggag acgcaactgc agagcatttt 200

 cgaagaggtg gtgaaaacgg aagttataga agaggctttt cctggcatgt 250

 ttatggatac tcctgaagat gagaaaacaa aactaattag ctgtttgggg 300

 gccttcagac agttttgggg tggtctttct caggagtctc atgaacagtg 350

 tatccagtgg attgttaagt ttattcatgg tcagcatagt cctaaaagaa 400

 tttcttttct ttatgactgc ttagcaatgg cagttgagac tggtctcctt 450

 ccacccaggc tggtttgtga atccctgata aactctgaca ctcttgagtg 500

 ggaaagaaca cagctttggg ccttaacatt taaactggtt cggaaaataa 550

 ttgggggagt ggattacaag ggtgttcgag atctcttaaa agtgattttg 600

 gagaagattt tgacaattcc taatacagtg agctctgctg ttgtacagca 650

 gcttctggca gcaagagagg ttatagcata tatcttggaa agaaatgcct 700

 gcttattacc agcctatttt gcagtcactg agatcaggaa actgtatcct 750

 gaaggcaaac ttccacactg gttacttgga aacctagtat cagactttgt 800

 ggataccttc aggcccacag caaggataaa ctccatttgt ggtcgctgta 850

 gtcttctgcc agttgtaaat aattcgggtg ccatttgtaa ttcatggaaa 900

 ctggatcctg ctactcttcg ttttcctttg aaaggccttt tgccatatga 950

 taaggatctg tttgaaccac agactgcttt gttgagatat gtattggagc 1000

 agccttattc cagggatatg gtctgcaata tgctaggttt aaataagcag 1050

 accttgaaca ttgctcagca caagcagcgc tgccctgtgc tggaggacca 1100

 gttggtggat ctggttgttt atgccatgga gcgatctgag accgaggaga 1150

 agtttgacga tgggggaaca agccaactcc tgtggcagca tctctcaagt 1200

 cagctcattt tctttgtgct tttccagttt gcaagttttc cacatatggt 1250

 gctttctctt catcagaagt tagcagggcg aggactgatt aaaggcagag 1300

 atcatcttat gtgggttctc ctgcaattca tttctggaag tattcagaaa 1350

 aatgcactag ctgattttct ccctgtgatg aagctcttcg acttgctata 1400

 cccagaaaaa gaatatatcc cagttcctga tattaacaaa ccccagtcaa 1450

 cccatgcctt tgcaatgacc tgtatttgga ttcatctcaa tagaaaagct 1500

 caaaatgaca actccaagct acagattcca atacctcatt ccctaagact 1550

 tcaccatgag ttcctgcagc agagtctaag aaataaaagt ttacagatga 1600

 atgactataa gattgctcta ttgtgtaatg catactctac aaattcagaa 1650

 tgttttacat tacccatggg agctctggta gaaactattt atggaaatgg 1700

 aattatgagg atacctctcc ctggaacaaa ctgtatggct tcaggatcta 1750

 ttaccccctt acctatgaac ctcctggatt cactgacagt tcatgccaaa 1800

 atgagcctta ttcacagcat tgcaaccagg gtgataaaac ttgctcatgc 1850

 aaagtccagt gtggccttgg ctccagccct agtggaaact tacagtcgtt 1900

 tattggtcta tatggaaata gagtctttgg gcatcaaagg atttatcagt 1950

 cagcttttgc caactgtttt caaatcacat gcatggggga tcttacacac 2000

 actccttgag atgtttagct accggatgca tcatattcag cctcattaca 2050

 gagttcagct cctgagtcat cttcatactt tggctgcagt tgcacaaaca 2100

 aaccagaacc agctccatct ttgtgtcgag agcactgctc tcaggcttat 2150

 aacagcatta ggtagctcag aggtacaacc gcagtttaca cgcttcctta 2200

 gtgatcccaa aacagtgctc tcagcagaat ctgaagaact gaaccgagcc 2250

 ttgatattga ccttggctag agcaactcat gtaacagatt tttttacagg 2300

 ctctgattca attcagggaa cttggtgtaa agacatactt cagaccatca 2350

 tgagtttcac tcctcataat tgggcttcac acaccctgag ctgttttcca 2400

 ggcccactac aggcattctt caaacaaaat aatgtgcctc aggaaagccg 2450

 ttttaatctg aaaaaaaatg tggaggagga gtataggaag tggaagtcaa 2500

 tgagcaacga aaacgacatt attacccact tctctatgca gggctcccct 2550

 cctctctttc tttgtcttct ctggaaaatg ctcttggaaa cagatcatat 2600

 taatcagatt ggctatagag tattagagag aattggagcc agggccttgg 2650

 tagcccatgt gaggacattt gcagatttcc tggtatatga gttttctaca 2700

 tcagcagggg gtcagcaact caataaatgc attgaaattc ttaatgacat 2750

 ggtatggaag tataacattg ttacactgga cagattaatt ctctgcctgg 2800

 ccatgcgtag tcacgaagga aatgaagccc aggtttgtta tttcataatt 2850

 cagttgctgt tactcaaacc aaacgatttt agaaatcgag taagtgactt 2900

 tgtgaaggaa aattccccag agcactggtt acagaatgac tggcacacca 2950

 agcacatgaa ttatcacaag aaatatccag agaagttgta ttttgagggc 3000

 ctcgcggaac aggtggatcc tcctgtacag atccagtctc cctatctgcc 3050

 catctatttt gggaatgtgt gtcttcgatt ccttccagta tttgatatag 3100

 taatccacag atttttagag ttgcttccgg tatccaaatc actggagact 3150

 ctactggatc atctaggagg cttatataaa tttcatgatc gtccagtgac 3200

 ttatctgtat aacactctgc actattatga aatgcacctg agagaccgcg 3250

 catttctcaa acgaaaactc gtccatgcga tcattggctc tctgaaggat 3300

 aatcgaccgc agggctggtg tctaagtgac acttacctga aatgcgctat 3350

 gaatgcacga gaggaaaatc cttgggttcc agatgacacc tactattgca 3400

 gattgattgg cagactagtc gatacgatgg ctggcaaatc tcctggtccc 3450

 tttccaaact gtgactggag attcaatgag tttcccaacc cagctgccca 3500

 tgctctccat gttacttgtg tggagctcat ggccttggca gtttcaggca 3550

 aagaagttgg gaatgccctt ctaaatgttg tcctaaaaag tcagccttta 3600

 gtgccaagag agaacattac agcatggatg aatgcaattg gtttgatcat 3650

 cactgcccta ccagagccat attggattgt tcttcatgat cgaattgtga 3700

 gtgtcatcag cagccccagc ttgacgtctg aaacagagtg ggttggctat 3750

 ccattccgcc tctttgattt cactgcctgt catcagtcct actctgagat 3800

 gagttgtagc tatacgttag ctcttgcaca tgctgtgtgg caccattcta 3850

 gcatcggaca actttctctc attccaaagt ttcttactga agtacttctt 3900

 cctatagtga agaccgaatt ccagttgctt tatgtatacc atcttgttgg 3950

 accattttta caaagatttc agcaagagag aactcgttgt atgatagaga 4000

 ttggtgtggc gttttatgac atgctgctga atgttgacca gtgtagcacc 4050

 catttaaatt acatggatcc catctgtgac ttcctctatc acatgaagta 4100

 tatgtttact ggtgacagcg tgaaagagca agtagagaag attatctgta 4150

 acttaaaacc agctttaaaa cttcgtcttc gattcatcac acacattagc 4200

 aagatggagc cagctgcagt gcctccacaa gccatgaaca gtgggtctcc 4250

 agcacctcag tctaatcagt aaaaagtcag agtacacagc aagggttcca 4300

 aattaagagg aagcaaaacg ctgcccagat cctgagaaac ctggagaaaa 4350

 tcaaccttag tagtttcaac tcatacattg tcttgtttga ttttgttctt 4400

 tgttttttat cctctttaag cacagatgcg tgttgaagtc taaggtgttc 4450

 tgtcatcaca ctctctttac tagaataagt gtgcccaggc agaaaaaaaa 4500

 gtgtattcaa tgttgctggc atgtgtggat tcacagctcg tggctgtaag 4550

 gaaatctggg ggtttcataa atccattaaa atccttttag agttgccaaa 4600

 aaaaaaaaaa aaaaaa 4616

<210> 5149
<211> 1365
<212> PRT
<213> Homo sapien

<400> 5149
 Met Glu Thr Gln Leu Gln Ser Ile Phe Glu Glu Val Val Lys Thr
   1               5                  10                  15

 Glu Val Ile Glu Glu Ala Phe Pro Gly Met Phe Met Asp Thr Pro
                  20                  25                  30

 Glu Asp Glu Lys Thr Lys Leu Ile Ser Cys Leu Gly Ala Phe Arg
                  35                  40                  45

 Gln Phe Trp Gly Gly Leu Ser Gln Glu Ser His Glu Gln Cys Ile
                  50                  55                  60

 Gln Trp Ile Val Lys Phe Ile His Gly Gln His Ser Pro Lys Arg
                  65                  70                  75

 Ile Ser Phe Leu Tyr Asp Cys Leu Ala Met Ala Val Glu Thr Gly
                  80                  85                  90

 Leu Leu Pro Pro Arg Leu Val Cys Glu Ser Leu Ile Asn Ser Asp
                  95                 100                 105

 Thr Leu Glu Trp Glu Arg Thr Gln Leu Trp Ala Leu Thr Phe Lys
                 110                 115                 120

 Leu Val Arg Lys Ile Ile Gly Gly Val Asp Tyr Lys Gly Val Arg
                 125                 130                 135

 Asp Leu Leu Lys Val Ile Leu Glu Lys Ile Leu Thr Ile Pro Asn
                 140                 145                 150

 Thr Val Ser Ser Ala Val Val Gln Gln Leu Leu Ala Ala Arg Glu
                 155                 160                 165

 Val Ile Ala Tyr Ile Leu Glu Arg Asn Ala Cys Leu Leu Pro Ala
                 170                 175                 180

 Tyr Phe Ala Val Thr Glu Ile Arg Lys Leu Tyr Pro Glu Gly Lys
                 185                 190                 195

 Leu Pro His Trp Leu Leu Gly Asn Leu Val Ser Asp Phe Val Asp
                 200                 205                 210

 Thr Phe Arg Pro Thr Ala Arg Ile Asn Ser Ile Cys Gly Arg Cys
                 215                 220                 225

 Ser Leu Leu Pro Val Val Asn Asn Ser Gly Ala Ile Cys Asn Ser
                 230                 235                 240

 Trp Lys Leu Asp Pro Ala Thr Leu Arg Phe Pro Leu Lys Gly Leu
                 245                 250                 255

 Leu Pro Tyr Asp Lys Asp Leu Phe Glu Pro Gln Thr Ala Leu Leu
                 260                 265                 270

 Arg Tyr Val Leu Glu Gln Pro Tyr Ser Arg Asp Met Val Cys Asn
                 275                 280                 285

 Met Leu Gly Leu Asn Lys Gln Thr Leu Asn Ile Ala Gln His Lys
                 290                 295                 300

 Gln Arg Cys Pro Val Leu Glu Asp Gln Leu Val Asp Leu Val Val
                 305                 310                 315

 Tyr Ala Met Glu Arg Ser Glu Thr Glu Glu Lys Phe Asp Asp Gly
                 320                 325                 330

 Gly Thr Ser Gln Leu Leu Trp Gln His Leu Ser Ser Gln Leu Ile
                 335                 340                 345

 Phe Phe Val Leu Phe Gln Phe Ala Ser Phe Pro His Met Val Leu
                 350                 355                 360

 Ser Leu His Gln Lys Leu Ala Gly Arg Gly Leu Ile Lys Gly Arg
                 365                 370                 375

 Asp His Leu Met Trp Val Leu Leu Gln Phe Ile Ser Gly Ser Ile
                 380                 385                 390

 Gln Lys Asn Ala Leu Ala Asp Phe Leu Pro Val Met Lys Leu Phe
                 395                 400                 405

 Asp Leu Leu Tyr Pro Glu Lys Glu Tyr Ile Pro Val Pro Asp Ile
                 410                 415                 420

 Asn Lys Pro Gln Ser Thr His Ala Phe Ala Met Thr Cys Ile Trp
                 425                 430                 435

 Ile His Leu Asn Arg Lys Ala Gln Asn Asp Asn Ser Lys Leu Gln
                 440                 445                 450

 Ile Pro Ile Pro His Ser Leu Arg Leu His His Glu Phe Leu Gln
                 455                 460                 465

 Gln Ser Leu Arg Asn Lys Ser Leu Gln Met Asn Asp Tyr Lys Ile
                 470                 475                 480

 Ala Leu Leu Cys Asn Ala Tyr Ser Thr Asn Ser Glu Cys Phe Thr
                 485                 490                 495

 Leu Pro Met Gly Ala Leu Val Glu Thr Ile Tyr Gly Asn Gly Ile
                 500                 505                 510

 Met Arg Ile Pro Leu Pro Gly Thr Asn Cys Met Ala Ser Gly Ser
                 515                 520                 525

 Ile Thr Pro Leu Pro Met Asn Leu Leu Asp Ser Leu Thr Val His
                 530                 535                 540

 Ala Lys Met Ser Leu Ile His Ser Ile Ala Thr Arg Val Ile Lys
                 545                 550                 555

 Leu Ala His Ala Lys Ser Ser Val Ala Leu Ala Pro Ala Leu Val
                 560                 565                 570

 Glu Thr Tyr Ser Arg Leu Leu Val Tyr Met Glu Ile Glu Ser Leu
                 575                 580                 585

 Gly Ile Lys Gly Phe Ile Ser Gln Leu Leu Pro Thr Val Phe Lys
                 590                 595                 600

 Ser His Ala Trp Gly Ile Leu His Thr Leu Leu Glu Met Phe Ser
                 605                 610                 615

 Tyr Arg Met His His Ile Gln Pro His Tyr Arg Val Gln Leu Leu
                 620                 625                 630

 Ser His Leu His Thr Leu Ala Ala Val Ala Gln Thr Asn Gln Asn
                 635                 640                 645

 Gln Leu His Leu Cys Val Glu Ser Thr Ala Leu Arg Leu Ile Thr
                 650                 655                 660

 Ala Leu Gly Ser Ser Glu Val Gln Pro Gln Phe Thr Arg Phe Leu
                 665                 670                 675

 Ser Asp Pro Lys Thr Val Leu Ser Ala Glu Ser Glu Glu Leu Asn
                 680                 685                 690

 Arg Ala Leu Ile Leu Thr Leu Ala Arg Ala Thr His Val Thr Asp
                 695                 700                 705

 Phe Phe Thr Gly Ser Asp Ser Ile Gln Gly Thr Trp Cys Lys Asp
                 710                 715                 720

 Ile Leu Gln Thr Ile Met Ser Phe Thr Pro His Asn Trp Ala Ser
                 725                 730                 735

 His Thr Leu Ser Cys Phe Pro Gly Pro Leu Gln Ala Phe Phe Lys
                 740                 745                 750

 Gln Asn Asn Val Pro Gln Glu Ser Arg Phe Asn Leu Lys Lys Asn
                 755                 760                 765

 Val Glu Glu Glu Tyr Arg Lys Trp Lys Ser Met Ser Asn Glu Asn
                 770                 775                 780

 Asp Ile Ile Thr His Phe Ser Met Gln Gly Ser Pro Pro Leu Phe
                 785                 790                 795

 Leu Cys Leu Leu Trp Lys Met Leu Leu Glu Thr Asp His Ile Asn
                 800                 805                 810

 Gln Ile Gly Tyr Arg Val Leu Glu Arg Ile Gly Ala Arg Ala Leu
                 815                 820                 825

 Val Ala His Val Arg Thr Phe Ala Asp Phe Leu Val Tyr Glu Phe
                 830                 835                 840

 Ser Thr Ser Ala Gly Gly Gln Gln Leu Asn Lys Cys Ile Glu Ile
                 845                 850                 855

 Leu Asn Asp Met Val Trp Lys Tyr Asn Ile Val Thr Leu Asp Arg
                 860                 865                 870

 Leu Ile Leu Cys Leu Ala Met Arg Ser His Glu Gly Asn Glu Ala
                 875                 880                 885

 Gln Val Cys Tyr Phe Ile Ile Gln Leu Leu Leu Leu Lys Pro Asn
                 890                 895                 900

 Asp Phe Arg Asn Arg Val Ser Asp Phe Val Lys Glu Asn Ser Pro
                 905                 910                 915

 Glu His Trp Leu Gln Asn Asp Trp His Thr Lys His Met Asn Tyr
                 920                 925                 930

 His Lys Lys Tyr Pro Glu Lys Leu Tyr Phe Glu Gly Leu Ala Glu
                 935                 940                 945

 Gln Val Asp Pro Pro Val Gln Ile Gln Ser Pro Tyr Leu Pro Ile
                 950                 955                 960

 Tyr Phe Gly Asn Val Cys Leu Arg Phe Leu Pro Val Phe Asp Ile
                 965                 970                 975

 Val Ile His Arg Phe Leu Glu Leu Leu Pro Val Ser Lys Ser Leu
                 980                 985                 990

 Glu Thr Leu Leu Asp His Leu Gly Gly Leu Tyr Lys Phe His Asp
                 995                1000                1005

 Arg Pro Val Thr Tyr Leu Tyr Asn Thr Leu His Tyr Tyr Glu Met
                1010                1015                1020

 His Leu Arg Asp Arg Ala Phe Leu Lys Arg Lys Leu Val His Ala
                1025                1030                1035

 Ile Ile Gly Ser Leu Lys Asp Asn Arg Pro Gln Gly Trp Cys Leu
                1040                1045                1050

 Ser Asp Thr Tyr Leu Lys Cys Ala Met Asn Ala Arg Glu Glu Asn
                1055                1060                1065

 Pro Trp Val Pro Asp Asp Thr Tyr Tyr Cys Arg Leu Ile Gly Arg
                1070                1075                1080

 Leu Val Asp Thr Met Ala Gly Lys Ser Pro Gly Pro Phe Pro Asn
                1085                1090                1095

 Cys Asp Trp Arg Phe Asn Glu Phe Pro Asn Pro Ala Ala His Ala
                1100                1105                1110

 Leu His Val Thr Cys Val Glu Leu Met Ala Leu Ala Val Ser Gly
                1115                1120                1125

 Lys Glu Val Gly Asn Ala Leu Leu Asn Val Val Leu Lys Ser Gln
                1130                1135                1140

 Pro Leu Val Pro Arg Glu Asn Ile Thr Ala Trp Met Asn Ala Ile
                1145                1150                1155

 Gly Leu Ile Ile Thr Ala Leu Pro Glu Pro Tyr Trp Ile Val Leu
                1160                1165                1170

 His Asp Arg Ile Val Ser Val Ile Ser Ser Pro Ser Leu Thr Ser
                1175                1180                1185

 Glu Thr Glu Trp Val Gly Tyr Pro Phe Arg Leu Phe Asp Phe Thr
                1190                1195                1200

 Ala Cys His Gln Ser Tyr Ser Glu Met Ser Cys Ser Tyr Thr Leu
                1205                1210                1215

 Ala Leu Ala His Ala Val Trp His His Ser Ser Ile Gly Gln Leu
                1220                1225                1230

 Ser Leu Ile Pro Lys Phe Leu Thr Glu Val Leu Leu Pro Ile Val
                1235                1240                1245

 Lys Thr Glu Phe Gln Leu Leu Tyr Val Tyr His Leu Val Gly Pro
                1250                1255                1260

 Phe Leu Gln Arg Phe Gln Gln Glu Arg Thr Arg Cys Met Ile Glu
                1265                1270                1275

 Ile Gly Val Ala Phe Tyr Asp Met Leu Leu Asn Val Asp Gln Cys
                1280                1285                1290

 Ser Thr His Leu Asn Tyr Met Asp Pro Ile Cys Asp Phe Leu Tyr
                1295                1300                1305

 His Met Lys Tyr Met Phe Thr Gly Asp Ser Val Lys Glu Gln Val
                1310                1315                1320

 Glu Lys Ile Ile Cys Asn Leu Lys Pro Ala Leu Lys Leu Arg Leu
                1325                1330                1335

 Arg Phe Ile Thr His Ile Ser Lys Met Glu Pro Ala Ala Val Pro
                1340                1345                1350

 Pro Gln Ala Met Asn Ser Gly Ser Pro Ala Pro Gln Ser Asn Gln
                1355                1360                1365

<210> 5150
<211> 455
<212> DNA
<213> Homo sapien

<400> 5150
 gaattcggca cgaggcccgg cgccactcgg cccagggcag ggaccccgcc 50

 acggccggga ccgcccggcc cggccccagc ccgcgcctct ccgcgccgcc 100

 ccgcgctccg caccgcgccc tctccgcgtc cccgcccgcg cggccggacc 150

 gggcagccag aaaaatcatt tttcttctct gggaaggtga acatttgtag 200

 cattgatttc ccggatctgg taacatggca aaagatactt ttaaagcgtc 250

 tgaagcggga tgaaggtgaa agatggaagg atctgatctc tgaagctgcg 300

 gtcaccaccc acaagttgtg gccttggata ccacactgca gttgggtggt 350

 gatggggtgg tgccttctga ctttttcctt atctttaccg actgtgttaa 400

 ttgataattt taaataaacg ccttaattaa caaaaaaaaa aaagcggccg 450

 ccgac 455

<210> 5151
<211> 138
<212> PRT
<213> Homo sapien

<400> 5151
 Glu Phe Gly Thr Arg Pro Gly Ala Thr Arg Pro Arg Ala Gly Thr
   1               5                  10                  15

 Pro Pro Arg Pro Gly Pro Pro Gly Pro Ala Pro Ala Arg Ala Ser
                  20                  25                  30

 Pro Arg Arg Pro Ala Leu Arg Thr Ala Pro Ser Pro Arg Pro Arg
                  35                  40                  45

 Pro Arg Gly Arg Thr Gly Gln Pro Glu Lys Ser Phe Phe Phe Ser
                  50                  55                  60

 Gly Lys Val Asn Ile Cys Ser Ile Asp Phe Pro Asp Leu Val Thr
                  65                  70                  75

 Trp Gln Lys Ile Leu Leu Lys Arg Leu Lys Arg Asp Glu Gly Glu
                  80                  85                  90

 Arg Trp Lys Asp Leu Ile Ser Glu Ala Ala Val Thr Thr His Lys
                  95                 100                 105

 Leu Trp Pro Trp Ile Pro His Cys Ser Trp Val Val Met Gly Trp
                 110                 115                 120

 Cys Leu Leu Thr Phe Ser Leu Ser Leu Pro Thr Val Leu Ile Asp
                 125                 130                 135

 Asn Phe Lys


<210> 5152
<211> 1442
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 21, 925-946
<223> Unknown base

<400> 5152
 tgcctggcct gacattttta naaaaagttt tattttgcac ggctctaaac 50

 ctccatgtta ttttccagtg gtgtagaagg taccagctaa agtgaaccac 100

 tatgtaatat taggccattc taaaggaaag atgttccatg tcatcagaga 150

 tggtaaaata ggcagggaaa aaaaaatctt tggtaccaaa gattacactt 200

 gtgtttctac acagcaaacc atttttcttt catgaaaata atatattatt 250

 aacatgaata tattattttg ctattaatgt gaaagttgtc tctaaatatt 300

 ttttaatttt caaactcata ctttattttc atttgaaatg tttttcacac 350

 cttttgcatt acataataat tttgtggaag cattttgccc tttagaataa 400

 atattagatt gatatagctg aaatgtgact tccagttctt tgatattccc 450

 cttgttattc aaatagaaat atggaaatgc tttatatatt actgttaaat 500

 ttcttagtgc agaaataaca ttattaatag agtattgttt tcaaaacaga 550

 tgattaattt caagaggttt aacagtgaaa ttgtgtcaat attttgcatt 600

 taaaatgaat ttaattgacc gatattttct gtagttaaat ttagtcacaa 650

 tatcacatat gttcttcaag aaacacatga aattattaat aaagtaatta 700

 aaaaattttt aatgtataac agaattgacc aataggccag ttttctggta 750

 acttatgata gtagattgtt tctttagaaa ctgggcagaa gctctgcatt 800

 ctcacttgta ctttgatttc ttatttcttg gtcaggcaat ttgaggaaag 850

 aagaaatggc atggggaata tatatgtttt gtttcttagg gaaaacagtc 900

 tgagaaatga ataaaaagca tgaannnnnn nnnnnnnnnn nnnnnntacc 950

 atggaaaagg atattcacag tagtacagtt ctcaatattt ttaattagat 1000

 gtcatatttt tttaatatag taaaaccttg ggatatagaa tattacatct 1050

 tttgagaatg tatgtgtctc taagtaagta aaatctaatg cgtataggag 1100

 actgatagct aaaaatgaat ggaacattaa tgtactttta taattaaacc 1150

 tcttatctat cagaaattgt aagagaatag atacatgttt tgaatgtaaa 1200

 gttgaaaagt ctggtttact gaataaattg aaagtgattt ataaaatcta 1250

 aatttggact acttgcaaat gataagctat tctagtagcc tttagtttaa 1300

 atccaacaga aatctagaag tcacaagcaa atatcttaaa ggtaaaatcc 1350

 atctgggcac tcatttaaag tatatcttaa aaaagcagca gcaaggtacc 1400

 ttgccatttt tagcatattt tcttcctttt tcttttttct tt 1442

<210> 5153
<211> 30
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 7
<223> unknown amino acid

<220>
<221> Unsure
<222> 21, 925-946
<223> Unknown amino acid

<400> 5153
 Pro Gly Leu Thr Phe Leu Xaa Lys Val Leu Phe Cys Thr Ala Leu
   1               5                  10                  15

 Asn Leu His Val Ile Phe Gln Trp Cys Arg Arg Tyr Gln Leu Lys
                  20                  25                  30

<210> 5154
<211> 1233
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 70
<223> Unknown base

<400> 5154
 catgctctaa acaggttagc tcctccatga catatagttt tggcatgaaa 50

 ggtggatcta aggctaccan agagaaagag ttagaaatga gtgtagactt 100

 cctctagcat cttttcatac ttaattaaga aagagaagga acttagcctt 150

 tatcatggta tagatttgat tgacttaggc ccacatatct gcaagggtca 200

 gccaaattta aattgtaaac atgtttttag aaaatctgaa ttccccagca 250

 cgattggctt gagcgattgg aaacaagatg caggacccca acacagacac 300

 tgagtggaat gacatcttag acaagaaggg catcttaccc accaaggaaa 350

 gtataaaaga atcagaagag aaggcagaag aggagcagca catccttcag 400

 cagtcagtgg tgacaacata cgaagatatg actttggaag agctggagga 450

 tcatgaagac gagtttaatg aggaggatga acatgctatt gaaatgtaca 500

 gatggcagag actcgctgag gggaaagcaa ttaaactgaa gaataaattt 550

 ggagaagttt tggagatttc agggaagtat tatgttctaa gaagttacca 600

 aagccagtga gggcttgtgg gtcatcttgc acctttgcaa acgaggaatt 650

 cccctctgtg ccctgataaa tcagcacctc agtggacttg ccaggaagtt 700

 tcctgatgtc aaaatttagt ctaaagccaa ttcaaccacc tgcataccca 750

 attatcctga taggaatctg cccatggtat ttgtttactt ggaaggagac 800

 atcaaggctc agttgatcgg tcctctggtg tttggcggca tgaacctgac 850

 cagagatgag ttggggtgga aactgtctga atctagagca gttaagacgg 900

 acttggagga aaaccctaag aagccgattg aaggtgtatt gctgtcttca 950

 gtgcagagct ctgtccccat gaggagggac agcgattcca agggtgactg 1000

 aggctgcagc tgctatcaca tgctgaactt tcttgtgaca aattgtctgg 1050

 atttctttaa gaaaaggaaa agcaagaatg aatccttctg gtttttagtt 1100

 ttgtataaat tatgtttcaa atctttacat tttagaaata ataattgctg 1150

 gaaattctgt taaatatttt ggaactcttt ttttaaacta tagtatttcc 1200

 tctaaaaaaa ttaaaaccag ctattggtat ggc 1233

<210> 5155
<211> 110
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 70
<223> Unknown amino acid

<400> 5155
 Met Gln Asp Pro Asn Thr Asp Thr Glu Trp Asn Asp Ile Leu Asp
   1               5                  10                  15

 Lys Lys Gly Ile Leu Pro Thr Lys Glu Ser Ile Lys Glu Ser Glu
                  20                  25                  30

 Glu Lys Ala Glu Glu Glu Gln His Ile Leu Gln Gln Ser Val Val
                  35                  40                  45

 Thr Thr Tyr Glu Asp Met Thr Leu Glu Glu Leu Glu Asp His Glu
                  50                  55                  60

 Asp Glu Phe Asn Glu Glu Asp Glu His Ala Ile Glu Met Tyr Arg
                  65                  70                  75

 Trp Gln Arg Leu Ala Glu Gly Lys Ala Ile Lys Leu Lys Asn Lys
                  80                  85                  90

 Phe Gly Glu Val Leu Glu Ile Ser Gly Lys Tyr Tyr Val Leu Arg
                  95                 100                 105

 Ser Tyr Gln Ser Gln
                 110

<210> 5156
<211> 2661
<212> DNA
<213> Homo sapien

<400> 5156
 aaaagttcca gttctttgag gtaagggttc ctgtttgcct cctatgtcta 50

 tcgatatttg cttttagaat ggtagttttc ctttttattc cttttctaga 100

 aagtaaagtc aacatggatt gatttaattt tttaaaaata gggcaccgtg 150

 gtttctcatg ccaatactgg tggaaaaatt tccatttgtt cgaaaatcag 200

 agagaacact ggaatgttac gttcataact tactaaggat tagtgtatat 250

 tttccaacct tgaggcatga aattctggag cttattattg aaaaactact 300

 caagttggat gtgaatgcat cccggcaggg tattgaagat gctgaagaaa 350

 cagcaaatca aacttgtggt gggacagatt ccacggaagg attgtgtaat 400

 atgggattcg cagaggcatt tttggaacct ctttggaaaa aattgcagga 450

 tccaagtaat cctgccatca tcaggcaggc tgctggaaat tatattggaa 500

 gctttttggc aagagctaaa tttattcctc ttattactgt aaaatcatgc 550

 ctagatcttt tggttaactg gctgcacata taccttaata accaggattc 600

 gggaacaaag gcattctgcg atgttgctct ccatggacca ttttactcag 650

 cctgccaagc tgtgttctac acctttgttt ttagacacaa gcagcttttg 700

 agcggaaacc tgaaagaagg tttgcagtat cttcagagtc tgaattttga 750

 gtggatagtg atgagccagc taaatcccct gaagatttgc ctgccctcag 800

 tggttaactt ttttgctgca atcacaaata agtaccagct cgtcttctgc 850

 tacaccatca ttgagaggaa caatcgccag atgctgccag tcattaggag 900

 taccactgga ggagactcag tgcagacctg cacaaaccca ctggacacct 950

 tcttcccctt tgatccctgt gtgctgaaga ggtcaaagaa attcattgat 1000

 cctatttatc aggtatggga agacatgagt gctgaagagc tacaggagtt 1050

 caagaaaccc atgaaaaagt tgttctggag aatcatgtag cgacagatga 1100

 agacgaacct gctttgaaac gccagcgact agaaatcaat tgccaggatc 1150

 catctataaa gtcattcctg tattccatca accagacaat ctgcttgcgg 1200

 ttggatagca ttgaagccaa attgcaagcc ctggaggcta cttgtaaatc 1250

 cttagaagaa aagctggatc tggtcacgaa caagcagcac agccccatcc 1300

 aggttcccat ggttgccggc tcccctctca ggacaaccca gatgtgcaac 1350

 aaagtgcgat ggtaagaaca gaccagggtg ccggggcctt caggtcactt 1400

 ggggagaagc gcgtcacctc ctcgcccagg cccgcagctt agtggctcag 1450

 tttgctggag atgcgcagtg tctgcctcag cagtctcagc agtttctaac 1500

 taaagctgac tttagttaga ccgaaaccga acacatggca tcctgccagg 1550

 atgacctgaa gtcatcctca cctttccttt ccacataaag ccggcccata 1600

 caccttttct ttggaactaa cccaccagat cttagaagat gtacacgtgc 1650

 ttctttcctt tttcctactc tacctggcta gtctttagat atgtttttct 1700

 tcgtatgtgg tgtttataca tttcacatga atatatcaaa cttttcattc 1750

 aaatctgcag tttttatttt gcttattttt aaaaagtaga gtctaatgag 1800

 tctaatctta gaaggctgtg tggtagtttg cgaactgttt gagtggaacc 1850

 tttatgatgt cttaagaagt ctcggacctg cttggtgtcc actcatccga 1900

 ggcttcctgt cagatattcc agctgacagc tcgcgctgaa gctcaggctc 1950

 tggtgttgct aaccttcccc acacctggcc agaaagaagt cctgcttaag 2000

 gcagtggaca cggcacagct ttgtgcttga caaggggcct tttgactgag 2050

 cgctgctcac ttcaggttcc ctggcctggc tgtagccttc tgcccggtgt 2100

 gtctgggagg agagagaatg gtgggacggc agtggggggg ccggggagga 2150

 catgtggatg ccgaggaatg ggagccgcaa caagcctgga gggactgttg 2200

 tgaccttgct gcccgtgtgt gctgcaggtg ccaccctgcc catgtgtgct 2250

 ggtggctggt gctgggttag gtgctttgtg gacctcgcca gggagtgtgg 2300

 gaagtctggg ggcagctcca catgatggct gctgtgctgg ctgaagcagt 2350

 ggtgcctctt tgagctctcg ggcatgccgg aagttttgga aacgctaccc 2400

 ggccgtcttc cgagtccgct gctggtggtg gagttggcat ctcatttcgc 2450

 aggcgggagc tggggatcgt tcacgtgtta ctctgagatg aggccttcgc 2500

 cctgcacaaa tgctgtcact cacatgtttc cccccagcag gagtttgttt 2550

 accatgtcct ctgtgcaggg acgctgttgg gctcccaggt caggtgtgca 2600

 aagctgttgg acccaatgcc ttttttttta ggatagtttt ttggggtaat 2650

 gtcctcttac c 2661

<210> 5157
<211> 310
<212> PRT
<213> Homo sapien

<400> 5157
 Met Pro Ile Leu Val Glu Lys Phe Pro Phe Val Arg Lys Ser Glu
   1               5                  10                  15

 Arg Thr Leu Glu Cys Tyr Val His Asn Leu Leu Arg Ile Ser Val
                  20                  25                  30

 Tyr Phe Pro Thr Leu Arg His Glu Ile Leu Glu Leu Ile Ile Glu
                  35                  40                  45

 Lys Leu Leu Lys Leu Asp Val Asn Ala Ser Arg Gln Gly Ile Glu
                  50                  55                  60

 Asp Ala Glu Glu Thr Ala Asn Gln Thr Cys Gly Gly Thr Asp Ser
                  65                  70                  75

 Thr Glu Gly Leu Cys Asn Met Gly Phe Ala Glu Ala Phe Leu Glu
                  80                  85                  90

 Pro Leu Trp Lys Lys Leu Gln Asp Pro Ser Asn Pro Ala Ile Ile
                  95                 100                 105

 Arg Gln Ala Ala Gly Asn Tyr Ile Gly Ser Phe Leu Ala Arg Ala
                 110                 115                 120

 Lys Phe Ile Pro Leu Ile Thr Val Lys Ser Cys Leu Asp Leu Leu
                 125                 130                 135

 Val Asn Trp Leu His Ile Tyr Leu Asn Asn Gln Asp Ser Gly Thr
                 140                 145                 150

 Lys Ala Phe Cys Asp Val Ala Leu His Gly Pro Phe Tyr Ser Ala
                 155                 160                 165

 Cys Gln Ala Val Phe Tyr Thr Phe Val Phe Arg His Lys Gln Leu
                 170                 175                 180

 Leu Ser Gly Asn Leu Lys Glu Gly Leu Gln Tyr Leu Gln Ser Leu
                 185                 190                 195

 Asn Phe Glu Trp Ile Val Met Ser Gln Leu Asn Pro Leu Lys Ile
                 200                 205                 210

 Cys Leu Pro Ser Val Val Asn Phe Phe Ala Ala Ile Thr Asn Lys
                 215                 220                 225

 Tyr Gln Leu Val Phe Cys Tyr Thr Ile Ile Glu Arg Asn Asn Arg
                 230                 235                 240

 Gln Met Leu Pro Val Ile Arg Ser Thr Thr Gly Gly Asp Ser Val
                 245                 250                 255

 Gln Thr Cys Thr Asn Pro Leu Asp Thr Phe Phe Pro Phe Asp Pro
                 260                 265                 270

 Cys Val Leu Lys Arg Ser Lys Lys Phe Ile Asp Pro Ile Tyr Gln
                 275                 280                 285

 Val Trp Glu Asp Met Ser Ala Glu Glu Leu Gln Glu Phe Lys Lys
                 290                 295                 300

 Pro Met Lys Lys Leu Phe Trp Arg Ile Met
                 305                 310

<210> 5158
<211> 2703
<212> DNA
<213> Homo sapien

<400> 5158
 ctcctttttg gaaatttttg gacacatcca ataacagacc agcttcgggc 50

 tatgaacaaa gcagcacacc aggagagcac tgaacacgtc ctgtctggag 100

 gagtggtagt gagtgctata ttcttcattt tgtctgccaa tatcttatca 150

 tctccctcta agagaggaca aaaaggtacc cttattggat attctcctga 200

 aggaacacct ctttataact tcatgggtga tgcttttcag catagctctc 250

 aatcgatccc taggtttatt aaggaatcac taaaacaaat tcttgaggag 300

 agtgactcta ggcagatctt ttacttcttg tgcttgaatc tgctttttac 350

 ctttgtggaa ttattctatg gcgtgctgac caatagtctg ggcctgatct 400

 cggatggatt ccacatgctt tttgactgct ctgctttagt catgggactt 450

 tttgctgccc tgatgagtag gtggaaagcc actcggattt tctcctatgg 500

 gtacggccga atagaaattc tgtctggatt tattaatgga ctttttctaa 550

 tagtaatagc gttttttgtg tttatggagt cagtggctag attgattgat 600

 cctccagaat tagacactca catgttaaca ccagtctcag ttggagggct 650

 gatagtaaac cttattggta tctgtgcctt tagccatgcc catagccatg 700

 cccatggagc ttctcaagga agctgtcact catctgatca cagccattca 750

 catcatatgc atggacacag tgaccatggg catggtcaca gccacggatc 800

 tgcgggtgga ggcatgaatg ctaacatgag gggtgtattt ctacatgttt 850

 tggcagatac tcttggcagc attggtgtga tcgtatccac agttcttata 900

 gagcagtttg gatggttcat cgctgaccca ctctgttctc tttttattgc 950

 tatattaata tttctcagtg ttgttccact gattaaagat gcctgccagg 1000

 ttctactcct gagattgcca ccagaatatg aaaaagaact acatattgct 1050

 ttagaaaagg ttacaggaat acttaaagat gctggagtaa acaatttaac 1100

 aattcaagtg gaaaaggagg catactttca acatatgtct ggcctaagta 1150

 ctggatttca tgatgttctg gctatgacaa aacaaatgga atccatgaaa 1200

 tactgcaaag atggtactta catcatgtga gataactcaa gaattacccc 1250

 tggagaataa acaatgaaga ttaaatgact cagtatttgt aatattgcca 1300

 gaaggataaa aattacacat taactgtaca gaaacagagt tccctactac 1350

 tggatcaagg aatctttctt gaaggaaatt taaatacaga atgaaacatt 1400

 aatggtaaaa gtggagtaat tatttaaatt atgtgtataa aaggaatcaa 1450

 attttgagta aacatgatgt attacatcat cttcaaaaat agatatgatg 1500

 gattctagtg aagaccaaaa ttacttctgt ttactttcta tcaggaagca 1550

 tctccattgt aaatatgtat ttacatgttt attacaaaga cccaaatgaa 1600

 aaatttttag tccatttttt gcatagccta aagataaaat aggaataaaa 1650

 gttctatatt tatggatttt ctgtatataa aactggtttc taattataac 1700

 ttaagtccat taagtaaaat ctgtattgcc actttaaatg taaactaaat 1750

 tatttgggag aaacttcaac cactgatatg agataagcaa tgagaatagg 1800

 gaagtgtata acatcacagt ttttgatgta ttacaaaaat caaccactct 1850

 ataaaataaa ttttttttac ttttggtaat atttgcaaat gaataattaa 1900

 tttattaggg taaagaactt atactaagtt gtgtccatgt tattcattta 1950

 cttaccatgt tcctttaaag tagaatattt cctttcttgt tatatatttg 2000

 acattccaag ctgcttatca agctggtatc caagcagtgg taagctttca 2050

 tcctttctta gctccataac gttgtgaaac agccagttaa gagaatcgta 2100

 aataattgtc aactcacagt tgaattctct gcctatgtag gtaacttttt 2150

 tctaatttct ggaacatata gatatataag aaatatcaaa gaataggtag 2200

 ttatttcaaa gtttaataag taaaacttgt tcataaacat ttgagcacca 2250

 tgaaatcaaa ataccctata actactttct atagtcatat ctaatttata 2300

 tttttttcat ttccagttgt aactagatat gtagtaaagt ctgaaaagac 2350

 tttaccatag acaataacat gcagttttat cagcaccaaa gaatgttgtc 2400

 caaaagaaac tttttaatac ctgtctttct atttataaca tctgaatatt 2450

 ttcattctta tattaagaat tttgataagt agattgaatt tagtatgagt 2500

 actattttct tatatatacc acaatggcaa acatgtatta taaatcatat 2550

 ttttgtctta ccaattttaa tatatgaggg gttttagaaa tttgttgtaa 2600

 gttattttta tattccttgt cttttgcata ttttttggcc aaaatcttca 2650

 atacatatta aaatttttga gtggtgggaa aataaaaaaa aaaaaaaaaa 2700

 aaa 2703

<210> 5159
<211> 409
<212> PRT
<213> Homo sapien

<400> 5159
 Leu Leu Phe Gly Asn Phe Trp Thr His Pro Ile Thr Asp Gln Leu
   1               5                  10                  15

 Arg Ala Met Asn Lys Ala Ala His Gln Glu Ser Thr Glu His Val
                  20                  25                  30

 Leu Ser Gly Gly Val Val Val Ser Ala Ile Phe Phe Ile Leu Ser
                  35                  40                  45

 Ala Asn Ile Leu Ser Ser Pro Ser Lys Arg Gly Gln Lys Gly Thr
                  50                  55                  60

 Leu Ile Gly Tyr Ser Pro Glu Gly Thr Pro Leu Tyr Asn Phe Met
                  65                  70                  75

 Gly Asp Ala Phe Gln His Ser Ser Gln Ser Ile Pro Arg Phe Ile
                  80                  85                  90

 Lys Glu Ser Leu Lys Gln Ile Leu Glu Glu Ser Asp Ser Arg Gln
                  95                 100                 105

 Ile Phe Tyr Phe Leu Cys Leu Asn Leu Leu Phe Thr Phe Val Glu
                 110                 115                 120

 Leu Phe Tyr Gly Val Leu Thr Asn Ser Leu Gly Leu Ile Ser Asp
                 125                 130                 135

 Gly Phe His Met Leu Phe Asp Cys Ser Ala Leu Val Met Gly Leu
                 140                 145                 150

 Phe Ala Ala Leu Met Ser Arg Trp Lys Ala Thr Arg Ile Phe Ser
                 155                 160                 165

 Tyr Gly Tyr Gly Arg Ile Glu Ile Leu Ser Gly Phe Ile Asn Gly
                 170                 175                 180

 Leu Phe Leu Ile Val Ile Ala Phe Phe Val Phe Met Glu Ser Val
                 185                 190                 195

 Ala Arg Leu Ile Asp Pro Pro Glu Leu Asp Thr His Met Leu Thr
                 200                 205                 210

 Pro Val Ser Val Gly Gly Leu Ile Val Asn Leu Ile Gly Ile Cys
                 215                 220                 225

 Ala Phe Ser His Ala His Ser His Ala His Gly Ala Ser Gln Gly
                 230                 235                 240

 Ser Cys His Ser Ser Asp His Ser His Ser His His Met His Gly
                 245                 250                 255

 His Ser Asp His Gly His Gly His Ser His Gly Ser Ala Gly Gly
                 260                 265                 270

 Gly Met Asn Ala Asn Met Arg Gly Val Phe Leu His Val Leu Ala
                 275                 280                 285

 Asp Thr Leu Gly Ser Ile Gly Val Ile Val Ser Thr Val Leu Ile
                 290                 295                 300

 Glu Gln Phe Gly Trp Phe Ile Ala Asp Pro Leu Cys Ser Leu Phe
                 305                 310                 315

 Ile Ala Ile Leu Ile Phe Leu Ser Val Val Pro Leu Ile Lys Asp
                 320                 325                 330

 Ala Cys Gln Val Leu Leu Leu Arg Leu Pro Pro Glu Tyr Glu Lys
                 335                 340                 345

 Glu Leu His Ile Ala Leu Glu Lys Val Thr Gly Ile Leu Lys Asp
                 350                 355                 360

 Ala Gly Val Asn Asn Leu Thr Ile Gln Val Glu Lys Glu Ala Tyr
                 365                 370                 375

 Phe Gln His Met Ser Gly Leu Ser Thr Gly Phe His Asp Val Leu
                 380                 385                 390

 Ala Met Thr Lys Gln Met Glu Ser Met Lys Tyr Cys Lys Asp Gly
                 395                 400                 405

 Thr Tyr Ile Met


<210> 5160
<211> 3804
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 607-674, 2124-2188
<223> Unknown base

<400> 5160
 acgaatttag aatataggta gtgttcttgg aatactttta gaatatgttg 50

 gaataaagtc atcctttctc attttctgaa aaagcaggga agaagcaaca 100

 gtttggtttt gatgagtttg gaattttctg ccacttgtag tgataaatgt 150

 tcttagcaga agcacgtggc agcattaaac ttaaaaatta atatcagtac 200

 gtatgttaat aattttaact agttttattt tagaaggata aggatattct 250

 gactagatta cagtaacatc tacaattgca atttctatga cagtaaattt 300

 agcttctata aaacgtaaag aacctttagt aaaacagcag ggaattgagt 350

 atcatctgtt gaataaataa atttatcatt ttatcctgcc agaagtatga 400

 tgggcatctt ccaatagaaa taaaagctgt tcctgagggc tttgtcattc 450

 ccagaggaaa tgttctcttc acggtggaaa acacagatcc agagtgttac 500

 tggcttacaa attggattga ggtaaattgt ttttttaatt cttatttaac 550

 attaattgaa taaagaccat tgaactgaga ttacagttta gaatttgtta 600

 ctaatannnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 650

 nnnnnnnnnn nnnnnnnnnn nnnngactaa ataatcttta aggtttcttc 700

 tagtagaata gaatgttctg agattttgtt taaatcaaat tattgagagt 750

 gattgttttt aaaacctagt tggctttcat ctaattcatt gccattttaa 800

 gtgtgtatta ttttagagca aacttagaaa aacagcacat ttctagtaac 850

 ttacgacatt cgatgaatga taaatgttca agttagacta aaggaacttt 900

 attccaactt ctagtaacta ctttcttcat ttttctctca tcagtttagg 950

 tcttaggatc taccatctgt tacttttcag tttctcatct aaataaaaca 1000

 agatctgctg ttcatattgt ttaatttctc aggaagggta cattttgggc 1050

 tttgggttta tactgcgagc cttttttttg tttttcttgt atgtatacct 1100

 aagtagtcat atgttttcac atggtcagag ttttgataat aatactctac 1150

 ctagcttctg aacagtttaa taatagattt aatccgtgag aggaaatacc 1200

 ctcgaaagtt actatagaaa taacacctta ctatctggtg gcatttactt 1250

 agttcttaga actgactaat tagtttatcg gttaaagtaa tttgctatta 1300

 tattgtaaaa tagtacattt gaggctcact tataaaaatt ggaaaacatc 1350

 gaaatataag aggtccaaga gggtgtttga aacacatttt gctaagttga 1400

 caggaaatta atagactttt tatgggccat taactaataa tacactcaaa 1450

 aaaaaggtac agttaaataa aggttttaaa tagtctatac cgtatactaa 1500

 aactaaatta atatttagga ctgaaataac atattgatta agtaccagct 1550

 atgtacccaa aaaatgctgg gcacagaagt tagagtaaga tgttttactt 1600

 aaagggcctt tgagtgagag ttggcaattc attctgaact aaccactaat 1650

 atcattaaga attagtgctg agttggtagc aggaaatagg taattctgtc 1700

 taaaggaatc atgaaatgga aaataaataa gcttttaata aggagaagga 1750

 agagctgaag aaatggcaca gtgttcttag aatgacagat agtcctatgg 1800

 ggactgcagc ataaaagtga aaaatgtata agataaacct ttagatggta 1850

 agcaaggcaa gattctcaaa ttctgtatga atcagctcca cctccgcccc 1900

 atggacagta gatgaccgtt aatggctttt aaggaaagat gcaacctgga 1950

 aaaaaaaaga aaaaaacttg ttttagaatg gtaaccactg gcaatatgaa 2000

 gaataattag actaaagaag agaggtagga taatcatggg cattggcagt 2050

 ggaattgaaa gagtaatttc agaagcagaa tggtcagatg ttggaggtga 2100

 ttggttatag agtttaagaa ttgnnnnnnn nnnnnnnnnn nnnnnnnnnn 2150

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnncc tgattctgtg 2200

 gttgactgga tggtcgtctg ctgctcttgc ttagacttag gcatctgcat 2250

 ttagctgagg gttcagccag ggctggacat cctttaatgg cctcattccc 2300

 atgtctgggg cctcaggtca gatagctggg actaccgggt ctcactccag 2350

 aagaggcttc ttcagagcat ggtagtcttg gggttctaag agaatgagag 2400

 tagaagctgc aaaacctctt gaaactgggg cttgggagtc acacatgact 2450

 ttctccacat tctgttcgtc aaaagcgaat cataaggaca gcacagactc 2500

 aagggataag aaaggagatt ccatctcttg atgagaagag ctgcaaaggc 2550

 catatttaat cagtcacagg agtctaatgc tacaaagtag ttttttaaaa 2600

 agatgactag attggcaagt tcaaggttaa tctttttatt tgttttattt 2650

 atatatcact tagctggtat tcagtaaaag cttgctttgt aaaatttagt 2700

 taatatcttt ttggttcagc acagacattg catcatctta gcagctcttt 2750

 ttcaaacaga tttgaagctg cttcaaataa caatctggtt tataaaatga 2800

 aaatagaaaa ttatgatctt agaatgaaga agtgaatttc taagccatga 2850

 taattattac ggttgctgtg attagacaga cttttctgtg gagcttcctg 2900

 acaaccaaga aaaaagggga aatcaaggaa ctgttcttat cagaaagtag 2950

 gaacccagca attctttcat tttctcattg ggaacttaat agtcactgaa 3000

 ttacaaagta gacagtgacc ttgattatac aacatatgcg gaagtgtttc 3050

 ctgtaactta cgtgagtatt ttatcaaata cttatatatt tgataaaagc 3100

 taagtacata aagcataact cagtagatag aattctctag tagtaagcta 3150

 aagtgcttca agtattagtt gtcatattaa tccaagagaa aattagatct 3200

 gagactacct cgaggagtaa acgaacaact tctttaaacc aatactagtc 3250

 aaaatgcagt ccacggacca atgctggttc atgccctatt tgatccaagt 3300

 ccacattaag tacagaaatg aagagtaagc atttagaaac ttggggcaat 3350

 ttgacattgc ctcaacatcc aagtttcagt gtcctttata aactattgat 3400

 ccatgacaga tcatgaaact ttctaaaaat tgatcctttt atcacatagt 3450

 ctttcaaaat attatttgct tctttgaagc tttggataga aacttgataa 3500

 tgtgaagttc tctgctatgt ggacctggtg tgcttatctt ctttgttgct 3550

 gatttgagag ctgagctatg tactatatct ggaatgcaca cagcaggcat 3600

 cctgctgtgc agttctgtgt ctagttaata gtatggaagt tcacattatc 3650

 aagtttctat ccaaagcttc aaagaagcaa ataatatttt gaaagactat 3700

 gtgataaaag gatcaatttt tagaaagttt catgatctgt catggatcaa 3750

 tagtttataa aggacactga aacttggatg ttgaggcaat gtcaaattgc 3800

 ccca 3804

<210> 5161
<211> 8
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 607-674, 2124-2188
<223> Unknown amino acid

<400> 5161
 Met Leu Arg Gln Cys Gln Ile Ala
   1               5

<210> 5162
<211> 1863
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1293-1365, 1835
<223> Unknown base

<400> 5162
 ggagacgggc agaaggcagt cagcacgggt gacactacag ggaccgtgga 50

 ggaagcctca cgggagtagc agccgcggag ctccagctca gccccacccc 100

 agggcccggc tgctccccca ggcctgggtc gggtctgttt ggcgactccc 150

 tggccccagc ctccgcccca gggaaaccga ggctgcgtcc aaaacccaga 200

 gtagcccgct gggggccggg gcggggtctc ggccaccctg gtggtgcaaa 250

 caggaaggat gcgcctggtt ttggctttaa tgttcaaaat ggaaaaaaat 300

 acaagaaagt tgtacagtat ttttcctgta aaggttatta ttctacatag 350

 aacaaaaagg aagaaagcag gcgtggtgag agtgcagacc cgcctgggcc 400

 cggcctgagg ttggaggctc agtcccgttt atcctgtggg atttggtcca 450

 gggtttttgt agaggcctta actgtttgag gctgtctgtc ttcacaatag 500

 cactgcatgg gagctgcgtg attccaactc ttaacttgaa ttttgtagag 550

 acaagaaaaa aggactatta ctgttgatcc aagtttgtag ttaatttaac 600

 atttgagttc tctcttggtg atgcgtgtgg ctttataggg cttttttttt 650

 tttccagttt gttttattac tttgtttggg atgcttcttc gctggtgcag 700

 tctacccaga ttgggttccc tttgcaaaac atcccccttc ctggagatga 750

 tgatgccatc gaagcccggg ccagggcctg acctggcagg cacacacctg 800

 gccagtggct ctgaggtccc cggggaccga gtcccctgcg agggcaggct 850

 gcccgaggcc acacctgccc accttcccta ctccaggcca ccagctggtg 900

 tcagattggg ccaccgggag agaacaggcc taggagggaa tggaaggctg 950

 gcggggaggc tgtcatccag aagcctcctc cccagaggtc tccaggagga 1000

 acctggctca actggggggc agtggtttac ttttcccttt tttcttcctt 1050

 tcttttgtcc tctcagctgc ccacagccag aaagccagga ccacccgaac 1100

 tggacaggga gcagggaggg aggagtggtc gcacggagcg tacctgattc 1150

 aacaggaaat cagttatttt ctaaaacagc ccctaccaga gcctcctgaa 1200

 ctctgtgggc accacgtgct gctgtgagca tctgcccaga cagtgacccg 1250

 ccacaggccc cgggcgtctg tggaaggagt tttgtaaagg aannnnnnnn 1300

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1350

 nnnnnnnnnn nnnnngaaga tgccgacagt gcggagtcta gccttttgta 1400

 aacttcatat tgcacactag gactataagc cattgctagc tcattttgaa 1450

 ttttaacgtg taatttttgt tttattttct ttctgtgggg aaacaatgct 1500

 tgatccacca atgctctttt taatgtttta taactatgta tgtgtatata 1550

 tataaatatc aaataatatg tatgcacata tgtgtgtgta tatatctata 1600

 tgtatataca tatatagata tatagagata tatagagagg ttttgagaca 1650

 aaaaaaatac agaacgtgaa acccgagctg aacagcgtgt gctctgatta 1700

 cttgaatctg gtctcctcgg cacctggtta ttaagaactg aatatttttc 1750

 cacttgaatt tagtgctatt agaaatttaa tatatgtgtt ttatttattt 1800

 gatttttttt tttttttgca tgactgatgc aaggnttgac attttcactc 1850

 aataaaaact gga 1863

<210> 5163
<211> 148
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1293-1365, 1835
<223> Unknown amino acid

<400> 5163
 Met Pro Ser Lys Pro Gly Pro Gly Pro Asp Leu Ala Gly Thr His
   1               5                  10                  15

 Leu Ala Ser Gly Ser Glu Val Pro Gly Asp Arg Val Pro Cys Glu
                  20                  25                  30

 Gly Arg Leu Pro Glu Ala Thr Pro Ala His Leu Pro Tyr Ser Arg
                  35                  40                  45

 Pro Pro Ala Gly Val Arg Leu Gly His Arg Glu Arg Thr Gly Leu
                  50                  55                  60

 Gly Gly Asn Gly Arg Leu Ala Gly Arg Leu Ser Ser Arg Ser Leu
                  65                  70                  75

 Leu Pro Arg Gly Leu Gln Glu Glu Pro Gly Ser Thr Gly Gly Gln
                  80                  85                  90

 Trp Phe Thr Phe Pro Phe Phe Leu Pro Phe Phe Cys Pro Leu Ser
                  95                 100                 105

 Cys Pro Gln Pro Glu Ser Gln Asp His Pro Asn Trp Thr Gly Ser
                 110                 115                 120

 Arg Glu Gly Gly Val Val Ala Arg Ser Val Pro Asp Ser Thr Gly
                 125                 130                 135

 Asn Gln Leu Phe Ser Lys Thr Ala Pro Thr Arg Ala Ser
                 140                 145

<210> 5164
<211> 1064
<212> DNA
<213> Homo sapien

<400> 5164
 gacggtatcg ataagctgct atcgagttac tgccatttca ttaccctctt 50

 tctccgcacc cgacatagat tttttttcaa agttacatgt tttattttca 100

 tgtttgtaaa acgaagagct tttttctgga tggttttctt atcagctttt 150

 cacacaacag tcaagtaaac ctcgtggcac tagccagaaa tcgttgcaac 200

 tttggaactt ccaagacaat ctggcctcta tcaatgggca gacagcgacc 250

 ctcattcaaa atgaagctgc tagtcagtca cattcgacat tcattatctt 300

 cactggctac tcgtccacac tcagaacgct gttcactgtt aaaagtgtca 350

 ggttttaacc aagcgatttt ccattaaata ttctcccaga tgttctggaa 400

 gttttttcgt gtatctttgc atcttcagag ctgctccact gtgcctagcc 450

 agtttgtaac atttctgctg tgtttatgct gttgagcaga gatactgtgg 500

 gttctatgta gctcatagga ttattgcaat gatcaaatga aataatgttt 550

 tataatttta aagcaccata gaaagattta agttctatgt atttttaatt 600

 tttaattatg atttctttct cgactaacat atgtatgagg ctttttttcc 650

 catttcctag cgtgtatatt tttaaattct gtgtttattg attcctgttt 700

 taattgaatt tgaattgtgg acagaaaata ggtacatgtt aagactgatc 750

 tgttaatatt tgttgagatt tgctttatga cctagattat aacctgtttc 800

 tgtaaatgtt tcatgattgc ttgaaaagta tgcttgtttt ttagttgttg 850

 gatgtccatt agaccaaagt tgttaatttt gtagttcaaa ttttttccat 900

 tttactattc ttttgtcttc tacttgatct ctcagactct gagatgtgtt 950

 gaaattttct attctagtga acttaccaat ttctccctgt aattctgtca 1000

 attttagttt tatatatttt tatatatttt gaagtcttgt tataaataaa 1050

 taattataaa tata 1064

<210> 5165
<211> 96
<212> PRT
<213> Homo sapien

<400> 5165
 Met Phe Tyr Phe His Val Cys Lys Thr Lys Ser Phe Phe Leu Asp
   1               5                  10                  15

 Gly Phe Leu Ile Ser Phe Ser His Asn Ser Gln Val Asn Leu Val
                  20                  25                  30

 Ala Leu Ala Arg Asn Arg Cys Asn Phe Gly Thr Ser Lys Thr Ile
                  35                  40                  45

 Trp Pro Leu Ser Met Gly Arg Gln Arg Pro Ser Phe Lys Met Lys
                  50                  55                  60

 Leu Leu Val Ser His Ile Arg His Ser Leu Ser Ser Leu Ala Thr
                  65                  70                  75

 Arg Pro His Ser Glu Arg Cys Ser Leu Leu Lys Val Ser Gly Phe
                  80                  85                  90

 Asn Gln Ala Ile Phe His
                  95

<210> 5166
<211> 454
<212> DNA
<213> Homo sapien

<400> 5166
 tagaattaag gaattaacct tagagaatgt ttacatttta aagagtggag 50

 aagaatcaaa gagtagtcaa atatgataga aaatcctggg cgactatttc 100

 tgagttctgt tttgttttgt ttttttgccc tttaagtagc tctctttagt 150

 aggaaaggga agaatattga cttgggttag ttagttctga tttcaaattt 200

 cccctttatc acttacttgg cagtatttaa ccttttcaga gtgtttcact 250

 gtcagaaaat aggaattcag ggttgtgaag attacataaa ataaatacat 300

 aaagcacagt gcttgtgaca gagtttcttt aacttcatta gcaccttccc 350

 tgtgacttca agtatagaca ggacttttat acattagaat ggaatatttg 400

 tttaactttg tttatgtctc ttgttttctc cttccttttg cttccactta 450

 aaaa 454

<210> 5167
<211> 24
<212> PRT
<213> Homo sapien

<400> 5167
 Arg Ile Lys Glu Leu Thr Leu Glu Asn Val Tyr Ile Leu Lys Ser
   1               5                  10                  15

 Gly Glu Glu Ser Lys Ser Ser Gln Ile
                  20

<210> 5168
<211> 4445
<212> DNA
<213> Homo sapien

<400> 5168
 aggaatgaaa ggtcataagc cattagaaat agtggcatta ttatgcaata 50

 acaacaccct agctaacctg cttttgtcat ctgtagcact tacaataaag 100

 aatgatgacc ttccaaccct ggacactacc tcgataaagc aaaccagaga 150

 tcctctctac actttctatg gaagccataa aagttgccat caatatatcc 200

 actttcatag ttctatactt ttatactttc tagacttttt tatagacttt 250

 atgatcagat ctttttgtct cagaggatag gttttgcaag attcaaagga 300

 aaatcaaact ccttggttgt tccagctttg aagcttttgc ttcagtaaat 350

 ttgtttaaag aaccagatca cataccattt atcaaattct ttacttaagt 400

 cagaatactt tgcagacata catatttgga aaacaaactg tttcttgttc 450

 actagataga atctgtattg tagtaagaaa ctacttacaa ggtggctttc 500

 tttctgcttt gttactctat gtattactca ataatatatg tatggtcaca 550

 ggttcctgga gttgttttat ttctttatga cagacacatg agtatgcacc 600

 tctctctaat cctctgatgt cactgcagct tcagtctctc tcactctgtt 650

 tttgagtgcc ttcaaaatgc cagcatcctg gaacattctt ttcctgatct 700

 aaatcctacc tctgactatt tcattatcca tgaatattgg aattcaccca 750

 tattccaatg ggcttaactc tacaaactag ctaaaacctt ggacaagaat 800

 ttgaccgtat ttctgttttg ttcctccatg tcatttttag gttatatttt 850

 taacttttat ttatatctta tttcttcaca tatttcgtct ctctgttgaa 900

 agattttatc cttatttgac tcttcacttt ttttactttc accagaaatt 950

 tgacgttcct ttaaaattaa aggtcattga atgtcttttg aacacctttt 1000

 tctcaactga agtcttcctg aatgcctccc ctttctgatg aaaggatcct 1050

 gagtgctgct gttgctctgc cctgttccca tgtgcccact cccttccgta 1100

 cacattttgc aagactatac tctttatttt agtcaaatta atttaaaatt 1150

 gctccctggg tttctgctct ctcatggccc tgtccctcaa aaacttctgt 1200

 ttactttttc tagctgtttt catctaattt gtttaaaatg tatgatggat 1250

 ccataatata tgaaggatgt aatgaaaagg aggttgcagt gttttatata 1300

 atatgatcga gcacctccgt gatgaaacat ttagcaattg gctagtcctt 1350

 cacagccaga gtggaagttt gtgctgtgga caggtctttt tactcccttc 1400

 cagttctcct ccaaaactgg acgaaaaagg aaaaaaaaaa agaactcttt 1450

 caaatgagga gatttgattg cattttttta ggtgaatgaa agcttggagt 1500

 tgagcatttg ggccttagtc agcatttttc ctttctgact taaaatctca 1550

 tgtccttttc cttaaagtta atagtactca ggtttttaag actaataacc 1600

 acacaaggtg ggtatctaag aaggcagctg ttaatacatt ctccatcttt 1650

 cctgtctggc aacaggaaag atattattgg tgagatagtg caaaattgtg 1700

 agaattggtt atgttcgatg atgaataaat tcaagatttt tgaaggcttc 1750

 actgctattt gggatgggaa ggtgagttta caaaatgaaa aaggtagatt 1800

 tttatgttac agaaatcagt aacgggtttc ttgttgtgtt aattaccttt 1850

 cacttgattt gccatgatgt ttcttcctca ttattgatct agaagtttgc 1900

 ctcttggata gtaactagca acttagtatc tactttaaaa tttgtggctt 1950

 ttctcttcag ggtcccaggc cataaaacaa cggagagctg tacttgcttg 2000

 tcacttggag gaaccacatc cttgagacag cctgctgtct tgtatgtctt 2050

 cagtaggaaa cttctgacac acacattcaa gggagttcct gcccctgaga 2100

 agtgttccca tagctttcca gtcgcaggtt actttcacac tacgtcagct 2150

 tctctggtga gatcagggat gttacatatt acttgaaaat gatttcatag 2200

 gaagtgagga tggggcaaga aaggaggtag aagctgaatt ttgcttaact 2250

 tcagaaggaa atctgatact tgccttggct agttctgatc aactaaagag 2300

 cctgtgtctg tactggatgt gccaaagagt caagttgttt ctggaatatc 2350

 cagctcctct gaatgaacac agcttcctcc ctacctgtct tttatgggtg 2400

 aaaagggacc gtctgatgag catgatagac atcctgtaca ggactcaaga 2450

 ctgtttcatt gcatttgaaa gttggtggga agtattttat tctgctagag 2500

 ctcctaaccc tcctagaaat atcttttcat gctctattaa ttcaattcat 2550

 tagtttaaaa agaaacagtg tgacataatt ttggtgttta cttcttaagt 2600

 tgtctcccca agggcatata tgtagcctct gaaaatggga tgatttcttc 2650

 tcaatcttcc ataaatttga atatgcattt tattcatttc ttgacatggg 2700

 ctgtgtgact gttttccatc agcagttctg gctttgtcca caagggagca 2750

 ataaagtacg ttagctttat tctcaacctt ctaaagaaag atcccacttt 2800

 taaatctctt ctggaatagc ctcttagctc aaagcttatt catgtatttt 2850

 gattatttaa gaaattttcc cttattacaa agtccagtcg tcgttcatcc 2900

 ctcatgatgc caagcaatga ttgatgtgtg ggtgtggagt ccttgtgggt 2950

 caggcatctt aattaattag actttttaca tattgatgat ccccagattg 3000

 aaagccagga ccttcccata ggggcgcctt tgtgtgctaa aggcagagca 3050

 ggcaggcttc tccactccta tctcctccgc aggccaccac catcacatct 3100

 ataggaggaa caagagcact gggggaactc tggagtatga gtaaggaaat 3150

 gcttctcacc ttctctgctc caaagagata tctgttacat cagggaacaa 3200

 gtcctctagg tcaggcactt cctcctgacc agtgcaacgg gcactccagg 3250

 ttagaaactg tgtgtgctcc ctctctgtca gttacttgtc taagggctcc 3300

 tatccgtggt catcagctct ctggccatga gttctgtttg tgcttattgc 3350

 agcagcatct tcacaacaaa caggtcagta atcaacctgg gaagggaaaa 3400

 gacgacagta aatattaccc cctgtagagc cgggaggcat ttacacctgg 3450

 aatggccttc ttaactgatt tctgcctggc cacctcaccc ccagccaagt 3500

 ctgaacctga gcaataccag gcacagagag gtgtctactt gtaactccaa 3550

 cacttgacaa aaaacaaaac tgaagctgtg attggtttag gcagcaagtg 3600

 gccaggtgca acttgtttgt ttttattttt gttttcccca acagtactga 3650

 gatcacttgc acttttcctc atttcttaag aaaatccagt ttgcttgcca 3700

 tgacttgttt agcgttaggt ttacaaagct tgttgttgaa tgttgaatat 3750

 ttgtccaaag gagtttgaca aaatagaagc tgcttggtcc ctgttctgcc 3800

 tgctaggtca taaggatgaa ggccatgtgg ctggggtact tatgtcaagt 3850

 ccagaatggg gcagtgtccc tctcctacct ctctgcggag acgcaattga 3900

 aggtcaagta gactcagtgt agggcaggca gctgtcatgc tgcaaagaag 3950

 tttagaggag tctttgggtt ggggaggtga caggtaggta ggacaggatc 4000

 tcttaagatg ggaaagatac tggggagagg agggctgctt ggccccaggg 4050

 aactgcagtg aggtggaact gagctccgct cctgaatctc caaaggagcc 4100

 catgctgccc ggcttccctg agtcattttt tccagcatcc tgtcagatcc 4150

 ctcaatgtac tgatttcccc cttgtgttaa ctataccgat attatttttt 4200

 tagcaattga aatgcacttt tttatttcaa ctcaatcatg attttaagta 4250

 taaaaaattt atagattgtt aaaactactt ttttgtgtat ttttaaccac 4300

 tcaatgtagc attgtatatt ttattcttgt gagactctgg tacaggtgtg 4350

 ccgcctaatg atttttctga gatgctgggc ctttggatgt gtacggtaac 4400

 caacttaatg ctaatgttca aagtaaaaaa aaaaaagcag ccata 4445

<210> 5169
<211> 92
<212> PRT
<213> Homo sapien

<400> 5169
 Gly Met Lys Gly His Lys Pro Leu Glu Ile Val Ala Leu Leu Cys
   1               5                  10                  15

 Asn Asn Asn Thr Leu Ala Asn Leu Leu Leu Ser Ser Val Ala Leu
                  20                  25                  30

 Thr Ile Lys Asn Asp Asp Leu Pro Thr Leu Asp Thr Thr Ser Ile
                  35                  40                  45

 Lys Gln Thr Arg Asp Pro Leu Tyr Thr Phe Tyr Gly Ser His Lys
                  50                  55                  60

 Ser Cys His Gln Tyr Ile His Phe His Ser Ser Ile Leu Leu Tyr
                  65                  70                  75

 Phe Leu Asp Phe Phe Ile Asp Phe Met Ile Arg Ser Phe Cys Leu
                  80                  85                  90

 Arg Gly


<210> 5170
<211> 474
<212> DNA
<213> Homo sapien

<400> 5170
 agtaaaaggg aagagagcat gtgtgatgta tattatatat aattttttac 50

 tcctggaacc cataaaagat aaaattttaa agcacgtaac gtcattggat 100

 gtcagacatt ctctgaattt acatatatta tctgggtgct gacaatacct 150

 ctttactcta cacatgaata aactgaggat tatagggcac acatgtcttg 200

 cctgagctca gatggttatg aaactagcaa tgaagctggg ctgggattct 250

 ccttctcgat gtttgaaagc agagtgtgta ctctaagcta cacacaatag 300

 aagacccttg agaatcacaa aataccaatt atttcaattg ataaatttgt 350

 gcaatgtgct cacatacatc actggcaaat atatccgttg ggataatttc 400

 taaattgcat ctagtaagaa agagttcatt aaacttttca ttttgttaca 450

 ttaaaatcca tttttcttcc ttgc 474

<210> 5171
<211> 46
<212> PRT
<213> Homo sapien

<400> 5171
 Val Lys Gly Lys Arg Ala Cys Val Met Tyr Ile Ile Tyr Asn Phe
   1               5                  10                  15

 Leu Leu Leu Glu Pro Ile Lys Asp Lys Ile Leu Lys His Val Thr
                  20                  25                  30

 Ser Leu Asp Val Arg His Ser Leu Asn Leu His Ile Leu Ser Gly
                  35                  40                  45

 Cys


<210> 5172
<211> 749
<212> DNA
<213> Homo sapien

<400> 5172
 aagcgaaaga atggaaaaag gagaagaaat ctaagggaag aagagacaga 50

 gaagagatct ggataacaga agaggactta gggatcactt aagcagttaa 100

 cctcatctaa attgaaaact tttcccatta aatggtaaaa taaatctttc 150

 tttcaagact aaaatttgag aattataaat gaaagctgtt ttctactaca 200

 gagaatcaaa ggaagtaaga ggatgaacat tgcaatgggc aaaaaaaatc 250

 ttaagacgaa ttcttgtggc caaatagcaa ataaccagtt caaaaacttt 300

 gcctctttac tgacacatgg gtggagatct caacagctgg ctttcttctc 350

 cctctctctg cctgcttgcc ttttcttcct acctcttctt cccttagatt 400

 tctttccttt tttccattct tcgccttaaa aaaaaaatct acttcctacc 450

 ttcatgtatc tttcctaatc atgatattga attaaagcac acttaaagta 500

 cattgctcat ttatgtcttt aattctcata gaatttattt ttgaatacag 550

 tatggcatta ggattctaac tttttaaata gataattaac cagagcacta 600

 tttcttaata tgccattgtt ttcttcttca tttgtagtga caataatgat 650

 tattattgag agcttgctat gggcaaagca gtgttttgag aggtttgcct 700

 gtatttaaat tcctggttgt gtttcttgaa taaaggtctt cctcatttt 749

<210> 5173
<211> 68
<212> PRT
<213> Homo sapien

<400> 5173
 Met Asn Ile Ala Met Gly Lys Lys Asn Leu Lys Thr Asn Ser Cys
   1               5                  10                  15

 Gly Gln Ile Ala Asn Asn Gln Phe Lys Asn Phe Ala Ser Leu Leu
                  20                  25                  30

 Thr His Gly Trp Arg Ser Gln Gln Leu Ala Phe Phe Ser Leu Ser
                  35                  40                  45

 Leu Pro Ala Cys Leu Phe Phe Leu Pro Leu Leu Pro Leu Asp Phe
                  50                  55                  60

 Phe Pro Phe Phe His Ser Ser Pro
                  65

<210> 5174
<211> 2101
<212> DNA
<213> Homo sapien

<400> 5174
 agagaaaatg aggggattaa tggactgtag ttctggacaa ggtggaaaac 50

 tcttaaagtg gaagtattgg ggcaagtgct ctgacaggct aggatggtgc 100

 agtcagtccc ttcacccaga aatcagtaga atgttaacag ttcagactca 150

 aaccttgtga aaaacaggtg gtggaaagga aatccctcac agcaactggc 200

 accataatca agacagaatg tttgcagaat aaatggagtt acctgctttc 250

 agccccaggt tgtagctatt gtctgccctg atgatatgtg ataataattt 300

 gtgatcctat tgtcttaaaa tggggtcact catctccagt agaattaagt 350

 ccacagtgaa gttgtccccc catccccaaa gagataaaca tatatgaatg 400

 aactcacatg ataacaacta ctgctgcctg ggatcatgag agacctgaac 450

 tgaactgata ggaagtgaaa ggtggctgag ataatgagaa tagacccatc 500

 tgcagaggat cataaaacca gcaaagacaa gatcttgtct aagatgcctt 550

 cacaaacttt gtccatgaga actctaagga cttctccaga cctgttggct 600

 gctgctgtga tctctgccca agaggagcct ctgaccaaca tccaaagggc 650

 ttctggaccc actggactcc tctggaggta ccttggtctc ccgatccatg 700

 gctgtggttt tttactccgt ttatcactcc tgtgtgtaga atgataattg 750

 cacaattgat agtgtgaaca cctcttgata aatggtaaat ctgagcatat 800

 gtatttggct gacatgtcat tgtgaaacct cacagcttca gtcagtgtca 850

 gcacagctag ggagcatgta cctaatgcac atatcactgg gcatagtcta 900

 caggcaccta ataactcagg taccttaaca gtcactaatg agtgtctctc 950

 caaggtctaa acaatggaag actgtagaag atgttattca ttaagatatc 1000

 tcaagaatgt ggaagactat tattcgcttc taaagggaca ggacttcata 1050

 gggcacctga agaaactccc atgaaaaatc acttttacaa aatgtcaagt 1100

 tatgatatcc aagatgaaac caatgagtca caacattcac ataatacact 1150

 gtacaaccct gatctcttga ctgtcatcaa atgtttctta cctctaaacc 1200

 aaagtttcat tttataattt aatttttctc attttttctg ttctcttagc 1250

 ttaagaaaag atcattacag actttttgta agtttttcat atatgcttgc 1300

 aaagggttgt aaaactttat tgtgattatt cttgctttaa gctgaaactt 1350

 ccctaatctt tctttagaga ttgtggcata gcatgttagt ttcttttcca 1400

 tatccaattg ttttctgtaa tgaatacaga aatatgggca ctattttgta 1450

 actttaaata gacatcatct caagtctaca agaattatcc aaaacggtat 1500

 ttaatgacat ttctaggtct tcagacacta ttaatgtaga ttgtagcctc 1550

 taggtcctga ggatttttac tggatactgg ttactgaaac tgagctttct 1600

 tgaattcttt ttccttccac tgtggtttcc cgcatttcaa cacatcacct 1650

 atttttgtcc tcaaacgtta cttaaatttt ttccacagaa ttaaattaaa 1700

 tatgaatcat ccctcctctg atttttgaaa tgaccctttg cttcctatga 1750

 taatgattct tctggtccgt tttgtagtta tatgttagag tttgtaaata 1800

 ttcacacatt ttgcaactgc atataatttt ctcatttttt cctcttcctc 1850

 taaagctgct gttatttctt ttaacttttt gtgggaaaaa ttaaacccat 1900

 ctttcacttt gttgatattt ataattgaac tccttgattt ttgcttgaat 1950

 tgcttttcaa gttacccact tttagggaag acattatttg ggttttgttt 2000

 agtgtatcag gcttttttta gttagttgta tcaagaagtg tagacttttc 2050

 tatacataat atcctttttc ccacagtagt tttttttttt tttaaagtct 2100

 a 2101

<210> 5175
<211> 86
<212> PRT
<213> Homo sapien

<400> 5175
 Met Arg Ile Asp Pro Ser Ala Glu Asp His Lys Thr Ser Lys Asp
   1               5                  10                  15

 Lys Ile Leu Ser Lys Met Pro Ser Gln Thr Leu Ser Met Arg Thr
                  20                  25                  30

 Leu Arg Thr Ser Pro Asp Leu Leu Ala Ala Ala Val Ile Ser Ala
                  35                  40                  45

 Gln Glu Glu Pro Leu Thr Asn Ile Gln Arg Ala Ser Gly Pro Thr
                  50                  55                  60

 Gly Leu Leu Trp Arg Tyr Leu Gly Leu Pro Ile His Gly Cys Gly
                  65                  70                  75

 Phe Leu Leu Arg Leu Ser Leu Leu Cys Val Glu
                  80                  85

<210> 5176
<211> 4383
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3058-3098, 3105, 3107, 3109, 3111, 3113
<223> Unknown base

<400> 5176
 caactacggc taggtacgag gctgggtgtc ggaggctccg ttgcctgctc 50

 ccggagggag acgcgctgcc gaggagaacc cagcgggaga acatttcagg 100

 ataggaatag gccaagtgct gagaagatga gtcttaggat tgatgtggat 150

 acaaactttc ctgagtgtgt tgtagatgca ggaaaagtca cccttgggac 200

 tcagcagagg caggagatgg accctcgcct gcgggagaaa cagaatgaaa 250

 tcatcctgcg agcagtatgt gctctgctga attctggtgg gggcataatc 300

 aaggctgaga ttgagaacaa aggctacaat tatgaacgtc atggagtagg 350

 attggatgtg cctccaattt tcagaagcca tttagataag atgcagaagg 400

 aaaaccactt tttgattttt gtgaaatcat ggaacacaga ggctggtgtg 450

 ccacttgcta ccttatgctc caatttgtac cacagagaga gaacatccac 500

 cgatgtcatg gattctcagg aagctctggc attcctcaaa tgcaggactc 550

 agactccaac gaatattaat gtttccaatt cattaggtcc acaggcagct 600

 cagggtagtg tacaatatga aggtaacata aatgtgtcag ctgctgcttt 650

 atttgataga aagcggcttc agtatctgga aaaactcaac cttcctgagt 700

 ccacacatgt tgaatttgta atgttctcga cagacgtgtc acactgtgtt 750

 aaagacagac ttccgaagtg tgtttctgca tttgcaaata ctgaaggagg 800

 atatgtattt tttggtgtgc atgatgagac ttgtcaagtg attggatgtg 850

 aaaaagagaa aatagacctt acgagcttga gggcttctat tgatggctgt 900

 attaagaagc tacctgtcca tcatttctgc acacagaggc ctgagataaa 950

 atatgtcctt aacttccttg aagtgcatga taagggggcc ctccgtggat 1000

 atgtctgtgc aatcaaggtg gagaaattct gctgtgcggt gtttgccaaa 1050

 gtgcctagtt cctggcaggt gaaggacaac cgtgtgagac aattgcccac 1100

 aagagaatgg actgcttgga tgatggaagc tgacccagac ctttccaggt 1150

 gtcctgagat ggttctccag ttgagtttgt catctgccac gccccgcagc 1200

 aagcctgtgt gcattcataa gaattcggaa tgtctgaaag agcagcagaa 1250

 acgctacttt ccagtatttt cagacagagt ggtatatact ccagaaagcc 1300

 tctacaagga actcttctca caacataaag gactcagaga cttaataaat 1350

 acagaaatgc gccctttctc tcaaggaata ttgatttttt ctcaaagctg 1400

 ggctgtggat ttaggtctgc aagagaagca gggagtcatc tgtgatgctc 1450

 ttctaatttc ccagaacaac acccctattc tctacaccat cttcagcaag 1500

 tgggatgcgg ggtgcaaggg ctattctatg atagttgcct attctttgaa 1550

 gcagaagctg gtgaacaaag gcggctacac tgggaggtta tgcatcaccc 1600

 ccttggtctg tgtgctgaat tctgatagaa aagcacagag cgtttacagt 1650

 tcgtatttac aaatttaccc tgaatcctat aacttcatga ccccccagca 1700

 catggaagcc ctgttacagt ccctcgtgat agtcttgctt gggttcaaat 1750

 ccttcttaag tgaagagctg ggctctgagg ttttgaacct actgacaaat 1800

 aaacagtatg agttgctttc aaagaacctt cgcaagacca gagagttgtt 1850

 tgttcatggc ttacctggat cagggaagac tatcttggct cttaggatca 1900

 tggagaagat caggaatgtg tttcactgtg aaccggctaa cattctctac 1950

 atctgtgaaa accagcccct gaagaagttg gtgagtttca gcaagaaaaa 2000

 catctgccag ccagtgaccc ggaaaacctt catgaaaaac aactttgaac 2050

 acatccagca cattatcatt gatgacgctc agaatttccg tactgaagat 2100

 ggggactggt atgggaaagc aaagttcatc actcagacag caagggatgg 2150

 cccaggagtt ctctggatct ttctggacta ctttcagacc tatcacttga 2200

 gttgcagtgg cctcccccct ccctcagacc agtatccaag agaagagatc 2250

 aacagagtgg tccgcaatgc aggtccaata gctaattacc tacaacaagt 2300

 aatgcaggaa gcccgacaaa atcctccacc taacctcccc cctgggtccc 2350

 tggtgatgct ctatgaacct aaatgggctc aagggtgtcc caggcaactt 2400

 agagattatt gaagacttga acttggagga gatactgatc tatgtagcga 2450

 ataaatgccg ttttctcttg cggaatggtt attctctgaa ggatattgct 2500

 gtgcttttca ccaaagcaag tgaagtggaa aaatataaag acaggcttct 2550

 aacagcaatg aggaagagaa aactgtctca gctccatgag gagtctgatc 2600

 tgttactaca gatcggtgat gcgtcggatg ttctaaccga tcacattgtg 2650

 ttggacagtg tctgtcgatt ttcaggcctg gaaagaaata tcgtgtttgg 2700

 aatcaatcca ggagtagccc caccggctgg ggcctacaat cttctgctct 2750

 gtttggcttc tagggcaaaa agacatctgt atattctgaa ggcttctgtg 2800

 tgacaggaaa cccaagccta agaaacaatt aagtggttct catctctaat 2850

 taactgtgaa accatttaat ccaaacatgt aagcacacac tcacttatta 2900

 agtcacatac ttttctaggt gctggggatt gagaacgaat cgatgtaaga 2950

 ttcctccttt agggcagaga cagaccactg acaaatacac agatagacaa 3000

 ggaatttccc atggtaaaaa gggatatcag taattagagg accgtgagac 3050

 tcagagannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntg 3100

 tccgngngng ngnacgtgca catgtgtgta ggtagatgga gggggtgatt 3150

 attttgggtg gtcagggaag tgctcagtga gggaagaact tgtcatgaga 3200

 atctctgagc gtgccaggca gactcggata tttttataaa tttttaacat 3250

 ggccacttgc agaagagctt gaatgggacg tgcagggaga atgggaagga 3300

 tggagcaggt agctcatctg gccttgtagg tgccgggaac gggcaagaca 3350

 tgttttgaaa tgtaagatca cagactgttt tttgcaagac cacattatat 3400

 tactttatta ttttctgctt tttcttttaa cgacattagt gtttttgatc 3450

 actatatttt aaaatgcttt ttgtgagcct tttggttatg tggaatctgt 3500

 tccttagctc tgatttttta ttcttatgga gcgtcttagg ttactacatg 3550

 aaggtaagac tgccacagtc ccccagggag gcacactgtg ttttactgat 3600

 tgatttgaag atgatagaga gcctaggggg atgagtctat tggactcaaa 3650

 ggttacattt tgtttttcca tttaatttaa taatcaacaa aacgacaaag 3700

 tcagtttaat atctttcttc tgctgagtct tcaggatgtt agctagtctt 3750

 tcaaaagcca ttgctacaaa agtgcaaatt tctcatttcc tgtgggtctc 3800

 tagaaactct ctcaatattt aaagccaaac aaatccatct tttctgagag 3850

 acagaaacta aaaaattcag agttaattca ctattaaaaa cagcaaggcc 3900

 ctgctatttc ccaagaataa agaaatttaa aattctcatt gtaagaagta 3950

 tgaacttgaa gctagaattg gtttatttct ggcagctact tacaatatta 4000

 agaactttac tttttaaatt tgagacaatt tcacaggaaa gcaagaaatt 4050

 agtctattgt gaaatgtttt tacaactaac ttggaatata ctgcaaatca 4100

 ctagtaagta gagacacatt taagataaaa tgattaataa aacaattggt 4150

 aattctgaat aaggatctga ataaatccag atcacagact gttcctttac 4200

 caatatgtaa aagaatgtgc aaaattcgta aaaatatacc caaaaattta 4250

 ccagcaacag agaagcaaag aatggagttc aaccttacac tataaacatc 4300

 taatagatat gtatgaaaat ttaaaaacta gaaaaggttg ggcatggtgg 4350

 ctcatgcttg tgatccccag gactttagga ggc 4383

<210> 5177
<211> 803
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3058-3098, 3105, 3107, 3109, 3111, 3113
<223> Unknown amino acid

<400> 5177
 Gln Leu Arg Leu Gly Thr Arg Leu Gly Val Gly Gly Ser Val Ala
   1               5                  10                  15

 Cys Ser Arg Arg Glu Thr Arg Cys Arg Gly Glu Pro Ser Gly Arg
                  20                  25                  30

 Thr Phe Gln Asp Arg Asn Arg Pro Ser Ala Glu Lys Met Ser Leu
                  35                  40                  45

 Arg Ile Asp Val Asp Thr Asn Phe Pro Glu Cys Val Val Asp Ala
                  50                  55                  60

 Gly Lys Val Thr Leu Gly Thr Gln Gln Arg Gln Glu Met Asp Pro
                  65                  70                  75

 Arg Leu Arg Glu Lys Gln Asn Glu Ile Ile Leu Arg Ala Val Cys
                  80                  85                  90

 Ala Leu Leu Asn Ser Gly Gly Gly Ile Ile Lys Ala Glu Ile Glu
                  95                 100                 105

 Asn Lys Gly Tyr Asn Tyr Glu Arg His Gly Val Gly Leu Asp Val
                 110                 115                 120

 Pro Pro Ile Phe Arg Ser His Leu Asp Lys Met Gln Lys Glu Asn
                 125                 130                 135

 His Phe Leu Ile Phe Val Lys Ser Trp Asn Thr Glu Ala Gly Val
                 140                 145                 150

 Pro Leu Ala Thr Leu Cys Ser Asn Leu Tyr His Arg Glu Arg Thr
                 155                 160                 165

 Ser Thr Asp Val Met Asp Ser Gln Glu Ala Leu Ala Phe Leu Lys
                 170                 175                 180

 Cys Arg Thr Gln Thr Pro Thr Asn Ile Asn Val Ser Asn Ser Leu
                 185                 190                 195

 Gly Pro Gln Ala Ala Gln Gly Ser Val Gln Tyr Glu Gly Asn Ile
                 200                 205                 210

 Asn Val Ser Ala Ala Ala Leu Phe Asp Arg Lys Arg Leu Gln Tyr
                 215                 220                 225

 Leu Glu Lys Leu Asn Leu Pro Glu Ser Thr His Val Glu Phe Val
                 230                 235                 240

 Met Phe Ser Thr Asp Val Ser His Cys Val Lys Asp Arg Leu Pro
                 245                 250                 255

 Lys Cys Val Ser Ala Phe Ala Asn Thr Glu Gly Gly Tyr Val Phe
                 260                 265                 270

 Phe Gly Val His Asp Glu Thr Cys Gln Val Ile Gly Cys Glu Lys
                 275                 280                 285

 Glu Lys Ile Asp Leu Thr Ser Leu Arg Ala Ser Ile Asp Gly Cys
                 290                 295                 300

 Ile Lys Lys Leu Pro Val His His Phe Cys Thr Gln Arg Pro Glu
                 305                 310                 315

 Ile Lys Tyr Val Leu Asn Phe Leu Glu Val His Asp Lys Gly Ala
                 320                 325                 330

 Leu Arg Gly Tyr Val Cys Ala Ile Lys Val Glu Lys Phe Cys Cys
                 335                 340                 345

 Ala Val Phe Ala Lys Val Pro Ser Ser Trp Gln Val Lys Asp Asn
                 350                 355                 360

 Arg Val Arg Gln Leu Pro Thr Arg Glu Trp Thr Ala Trp Met Met
                 365                 370                 375

 Glu Ala Asp Pro Asp Leu Ser Arg Cys Pro Glu Met Val Leu Gln
                 380                 385                 390

 Leu Ser Leu Ser Ser Ala Thr Pro Arg Ser Lys Pro Val Cys Ile
                 395                 400                 405

 His Lys Asn Ser Glu Cys Leu Lys Glu Gln Gln Lys Arg Tyr Phe
                 410                 415                 420

 Pro Val Phe Ser Asp Arg Val Val Tyr Thr Pro Glu Ser Leu Tyr
                 425                 430                 435

 Lys Glu Leu Phe Ser Gln His Lys Gly Leu Arg Asp Leu Ile Asn
                 440                 445                 450

 Thr Glu Met Arg Pro Phe Ser Gln Gly Ile Leu Ile Phe Ser Gln
                 455                 460                 465

 Ser Trp Ala Val Asp Leu Gly Leu Gln Glu Lys Gln Gly Val Ile
                 470                 475                 480

 Cys Asp Ala Leu Leu Ile Ser Gln Asn Asn Thr Pro Ile Leu Tyr
                 485                 490                 495

 Thr Ile Phe Ser Lys Trp Asp Ala Gly Cys Lys Gly Tyr Ser Met
                 500                 505                 510

 Ile Val Ala Tyr Ser Leu Lys Gln Lys Leu Val Asn Lys Gly Gly
                 515                 520                 525

 Tyr Thr Gly Arg Leu Cys Ile Thr Pro Leu Val Cys Val Leu Asn
                 530                 535                 540

 Ser Asp Arg Lys Ala Gln Ser Val Tyr Ser Ser Tyr Leu Gln Ile
                 545                 550                 555

 Tyr Pro Glu Ser Tyr Asn Phe Met Thr Pro Gln His Met Glu Ala
                 560                 565                 570

 Leu Leu Gln Ser Leu Val Ile Val Leu Leu Gly Phe Lys Ser Phe
                 575                 580                 585

 Leu Ser Glu Glu Leu Gly Ser Glu Val Leu Asn Leu Leu Thr Asn
                 590                 595                 600

 Lys Gln Tyr Glu Leu Leu Ser Lys Asn Leu Arg Lys Thr Arg Glu
                 605                 610                 615

 Leu Phe Val His Gly Leu Pro Gly Ser Gly Lys Thr Ile Leu Ala
                 620                 625                 630

 Leu Arg Ile Met Glu Lys Ile Arg Asn Val Phe His Cys Glu Pro
                 635                 640                 645

 Ala Asn Ile Leu Tyr Ile Cys Glu Asn Gln Pro Leu Lys Lys Leu
                 650                 655                 660

 Val Ser Phe Ser Lys Lys Asn Ile Cys Gln Pro Val Thr Arg Lys
                 665                 670                 675

 Thr Phe Met Lys Asn Asn Phe Glu His Ile Gln His Ile Ile Ile
                 680                 685                 690

 Asp Asp Ala Gln Asn Phe Arg Thr Glu Asp Gly Asp Trp Tyr Gly
                 695                 700                 705

 Lys Ala Lys Phe Ile Thr Gln Thr Ala Arg Asp Gly Pro Gly Val
                 710                 715                 720

 Leu Trp Ile Phe Leu Asp Tyr Phe Gln Thr Tyr His Leu Ser Cys
                 725                 730                 735

 Ser Gly Leu Pro Pro Pro Ser Asp Gln Tyr Pro Arg Glu Glu Ile
                 740                 745                 750

 Asn Arg Val Val Arg Asn Ala Gly Pro Ile Ala Asn Tyr Leu Gln
                 755                 760                 765

 Gln Val Met Gln Glu Ala Arg Gln Asn Pro Pro Pro Asn Leu Pro
                 770                 775                 780

 Pro Gly Ser Leu Val Met Leu Tyr Glu Pro Lys Trp Ala Gln Gly
                 785                 790                 795

 Cys Pro Arg Gln Leu Arg Asp Tyr
                 800

<210> 5178
<211> 761
<212> DNA
<213> Homo sapien

<400> 5178
 cggaaggccc gctgcacggg cgggtgcttg cagattcctc cagggccacc 50

 tgcaggcccc ggcgctggcc ccgtgagctc ggcccctccc gcgtcccccg 100

 cgcccaccca cggggccagc gagatccgca gccgtctcag gcttcccctg 150

 tcaccccggc cctgcgaagc gggtgtgcgc cccttagttc tccgagcccg 200

 ccgggagcca cctcctcccc tgcccctgga gggggccacg cccgcagaac 250

 gctgggcaga ggcgaaggaa ccgggaaacg tcccttttct ccacactgac 300

 cttcgggtct gctgggtcct ctccactccc tcccaccctg cccgcgctgt 350

 tccctggggc ccgcagtttc agcaaagttc cctgccgcgc cgggaagccg 400

 tcctgttgcc cactctcacc cttcctcctt tcccggccca ttctctctcc 450

 ccactgggtc tccgacacga ccctctctcc tcccggctgt ccccgagccc 500

 ctctctgctt ccccagctca gccccctctc tgacggcttc tccctcccac 550

 ccccaggcga atctccgggc tcccacgggg tgcccccgat ccccggggtc 600

 taggtcaacc gacaaaatta ttttaaatgg gaagatttga attccattga 650

 attcatggaa gcaggaatcc atctggtcat attttaaata attttgaaat 700

 gataatagca attatcaatt taaagtttaa ccagaattca gaataaccac 750

 cattttacca g 761

<210> 5179
<211> 200
<212> PRT
<213> Homo sapien

<400> 5179
 Arg Lys Ala Arg Cys Thr Gly Gly Cys Leu Gln Ile Pro Pro Gly
   1               5                  10                  15

 Pro Pro Ala Gly Pro Gly Ala Gly Pro Val Ser Ser Ala Pro Pro
                  20                  25                  30

 Ala Ser Pro Ala Pro Thr His Gly Ala Ser Glu Ile Arg Ser Arg
                  35                  40                  45

 Leu Arg Leu Pro Leu Ser Pro Arg Pro Cys Glu Ala Gly Val Arg
                  50                  55                  60

 Pro Leu Val Leu Arg Ala Arg Arg Glu Pro Pro Pro Pro Leu Pro
                  65                  70                  75

 Leu Glu Gly Ala Thr Pro Ala Glu Arg Trp Ala Glu Ala Lys Glu
                  80                  85                  90

 Pro Gly Asn Val Pro Phe Leu His Thr Asp Leu Arg Val Cys Trp
                  95                 100                 105

 Val Leu Ser Thr Pro Ser His Pro Ala Arg Ala Val Pro Trp Gly
                 110                 115                 120

 Pro Gln Phe Gln Gln Ser Ser Leu Pro Arg Arg Glu Ala Val Leu
                 125                 130                 135

 Leu Pro Thr Leu Thr Leu Pro Pro Phe Pro Ala His Ser Leu Ser
                 140                 145                 150

 Pro Leu Gly Leu Arg His Asp Pro Leu Ser Ser Arg Leu Ser Pro
                 155                 160                 165

 Ser Pro Ser Leu Leu Pro Gln Leu Ser Pro Leu Ser Asp Gly Phe
                 170                 175                 180

 Ser Leu Pro Pro Pro Gly Glu Ser Pro Gly Ser His Gly Val Pro
                 185                 190                 195

 Pro Ile Pro Gly Val
                 200

<210> 5180
<211> 943
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 795, 834
<223> Unknown base

<400> 5180
 ttatctcata atgcctttca taaccatttg acattataag tctacttaac 50

 cttaccctgc tattatcatc actgagaatt ttcctgagca ttgacatttt 100

 cttgcctttt tgtatgctat ttagcagttc tgcatttgaa gtgatcgtta 150

 ttagattgct gattgtagca tccttatctt aactatatag atgagaatga 200

 ggagtaaggc taagagtgtg cccagggact gtaagtgcca gcaccttcct 250

 acccccacta tgctgtccat taaggcagca gacagatgat atcaggctgt 300

 ctttcagcct gataatgagt gattgattac acaactcttt aagacctttg 350

 tcatctttgt ggtttttata aaagagcaca tatagggctg taagaccaag 400

 ctaatgaatt agttgtaaca tttatttctt attactattt ataatggtaa 450

 tttatgttga ttattgaaac atttgcaaaa tttaaatgtg cttagagaaa 500

 acagaaacca cttttgactt tgtgcatgct atttagcagt tctacatttc 550

 aagtgattgt tattagacat tatgactcac tccatcttaa ataaccaatt 600

 aatccattga ttcaacgttt tattttatgc ttgccatgta tgcaccaggc 650

 cctgttctag gcatttgaga tacagatctg tctcctgctc tcatgtactg 700

 tagtggagaa aactgaaaat aagccagtaa acaaataaat atacactttg 750

 tgatagctga taattcctat ttttgtattt cataccagca ctttnttcct 800

 tatgcataag tagatgtaaa aagtatctgg actntatggc atttttctag 850

 cctatttaat atgtatgaat gtaatgccag ggggatagaa tgacaatggc 900

 aatacagtgg ctaagagata tgtttgacaa agaaaaagga gat 943

<210> 5181
<211> 17
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 795, 834
<223> Unknown amino acid

<400> 5181
 Met Thr Met Ala Ile Gln Trp Leu Arg Asp Met Phe Asp Lys Glu
   1               5                  10                  15

 Lys Gly


<210> 5182
<211> 875
<212> DNA
<213> Homo sapien

<400> 5182
 gttcactaaa gctttggtga agactcacat gtagaaagat gtagctgttt 50

 tattgccggc ttttgttcag cagaaacaag caaatagaga atctttgaag 100

 ggcctctctg gtgtcagtag gaaatcctga tttttagcta cggttggtgt 150

 gcactaagtc atcttcagaa gttggtagga ttctgtgagt ccagaggaca 200

 gagcttatag aggcattagt attgtaggac taattgtgga tcctgggtgc 250

 cctgttaaag taacccttgt catcatttat gctaaagatg atacccttct 300

 ggcagtttgc cacagtacaa ttcagatgca tctgctttta acccttttcc 350

 gttatcattg gaagtctgac agtgcgctgc ataaacacct tgagtaccac 400

 agcattccgt aatatcaatt tctagaagaa gcctctttct aatagtagtg 450

 tggccggtgc ttattaatca tctagctact gagttactgt attggattaa 500

 aatatataaa gagagagcac accaaatcta tgcagattcc tttatcctag 550

 tatgtcagtt tccttttcta tctctcattt ttaccttatt tactgtaaca 600

 aagattgttg attttaaaga cttatgggta ccgtgctctc tttttagtta 650

 ggtaggttaa atgagtattc ataaaagcaa atgttatttt tctacattat 700

 gcagatattg aaattgtgta ttatgagcac cagtttggtt aagtactttt 750

 tgtggaacca gttagagcta atatctaaaa aaggaagaaa atgatttgtg 800

 gaaccagtta gagttaatat ctaaaaaagg aagaaaatga aaatttcgtg 850

 gtcgaagata atttgtttgg acaca 875

<210> 5183
<211> 13
<212> PRT
<213> Homo sapien

<400> 5183
 Met Lys Ile Ser Trp Ser Lys Ile Ile Cys Leu Asp Thr
   1               5                  10

<210> 5184
<211> 1732
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1655-1680, 1726
<223> Unknown base

<400> 5184
 caatgaacca tgctggatgt ttcgctggag ctgggatcct ttcaggacac 50

 tgtgcttgct gtgcccatcc agtcaaccaa ggaggtaccc ccctaccgtg 100

 cagagctgct ttgggcctcg atgccattgt tgccgaactg acattgccat 150

 gatgaaaatg gactgtaatt tgtacagcta tttgccagtt gttttttcta 200

 ttttgcactg tggaaatctt tgcccaaatt actgcaagag tctcgagcat 250

 cctgctgtcg taagtgcaga gtcaaaggaa gaaaacgatg attttttaaa 300

 ccatctttct gctttctagt ctcacctgag tgcctcacat ttggcagaat 350

 caacctggaa tcctgctcat aagactatca gggaaatata atttccagac 400

 ttccatttcc agaaaaatgt aataaatact tttaaagggg atggagatgg 450

 taccgtgtgc taaccccact ctgagacaaa cctgggtcac aggaaccata 500

 gggaagatgt ctgcagtaga aggggacctc gaagtactca agtacttggc 550

 tcacaacagc actattcaca taaagcctgg cctgcccctt ggtgacctcc 600

 ttcccttacg cctctagact ctactaggtg atcagaaatc cctgcaagct 650

 agttggggag ggaagagtga aagtgaaaaa tggagaggaa acactgctac 700

 ccgcccaatg cctgaagcca aatgcaagcc tgggccaggc ttgggggagg 750

 aatcaagagg aagcttaaac ttaaaatgaa atcgaaagtt tagactccta 800

 catgggattg gacattttaa atgctgaaca gagcctattt ttatagctag 850

 aagttacagg acaaattttt ggttaactga gaatgatcca aaaatcatgt 900

 gaattttgtg atccagaaag tcacagaaca tgccctagat tttatcccag 950

 gggcagggag gagtgacctg cagagcaagt ttgaattggt aaatagaaaa 1000

 caagaataaa atagtttgct gtttacattc ccataagcct ggctctttcg 1050

 acttcatggg tatattcctt ggttgaattt agtatgccac tatgacgccg 1100

 gattgtgata tttgcctagg atgttttggt cctaatattt agtatggaat 1150

 tatttgccca aatcacctgc ccctctccac ttgtagcttt atttcaagag 1200

 gtatgtttct caaagtggag tgactgccag agtgggagaa aggagctagc 1250

 ccttacagct gtagtaggtc tttgtacatc agcttggtaa atctgcaaag 1300

 ccccccacct tcccccctcc caccaccccc aatccccacc ccgccaggag 1350

 ccttccccac gtgtggacaa gagagaaggg aggatctggg aggatgtgct 1400

 gtttctcagg gtcccacagc tagaaggtgg tggagctaga atttaaatca 1450

 cattccaaat gtctaaaaat actaacatta tcacatatta ccagagacac 1500

 ctcaaaaaag acagagacgc cctgcagggc cgcaacattc ccgcagcctg 1550

 gtagggtctg ctgggggccc catgcctgtg agagccgctc ctgccgctgc 1600

 agcaccgggg aggctgtgca ttcaacgagt ccttcctccc ttctcctttc 1650

 attcnnnnnn nnnnnnnnnn nnnnnnnnnn ccctccgctc cttcccctag 1700

 accttccttc cgccctccct accccnctgc ca 1732

<210> 5185
<211> 105
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1655-1680, 1726
<223> Unknown amino acid

<400> 5185
 Asn Glu Pro Cys Trp Met Phe Arg Trp Ser Trp Asp Pro Phe Arg
   1               5                  10                  15

 Thr Leu Cys Leu Leu Cys Pro Ser Ser Gln Pro Arg Arg Tyr Pro
                  20                  25                  30

 Pro Thr Val Gln Ser Cys Phe Gly Pro Arg Cys His Cys Cys Arg
                  35                  40                  45

 Thr Asp Ile Ala Met Met Lys Met Asp Cys Asn Leu Tyr Ser Tyr
                  50                  55                  60

 Leu Pro Val Val Phe Ser Ile Leu His Cys Gly Asn Leu Cys Pro
                  65                  70                  75

 Asn Tyr Cys Lys Ser Leu Glu His Pro Ala Val Val Ser Ala Glu
                  80                  85                  90

 Ser Lys Glu Glu Asn Asp Asp Phe Leu Asn His Leu Ser Ala Phe
                  95                 100                 105

<210> 5186
<211> 1824
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1168-1248
<223> Unknown base

<400> 5186
 gtgggaggca ccctgagccc gctcgccctg gccaataagg cggagagtgt 50

 ggtgtccgtc accatgcccg gcatatatga agttttaaaa aatcagaata 100

 cagaacaaaa tttattggga gatgagcttc tttctttctc tcttcaacac 150

 catcgccaca tcacctccac atatacacac actgaaaaga tactgaaaag 200

 acataataac catgggaaat ggagattact ggattgttaa atgttctttt 250

 tgcctgtctt tattctctaa ctttgctata atgaacagaa attatttttt 300

 gataagcaaa aaatatttta actttaaaca tgtaaagtaa cttagtagtt 350

 gtcttttcaa aatatgtaag aatcattagt tcactagttg gttaaatatg 400

 tttttaatcc caacatcttg ataattgtcg caaaattgag ggaacatttt 450

 ttgaactcta aaatgctata gaattgacag atcatttttc agttcataag 500

 ttattactta taatcagttt ttttattgtt actatggcaa tattttatac 550

 acaagaatgg ctgaggttag gaatttgtgc cctgaaaatt gtatcaacat 600

 atcaaatatg aagtaaataa caatttcttg ctttaaatat aacaaagatg 650

 tgggaagaag tggtaggcaa gagtctctgt gttaccatgg gaacgattaa 700

 gttttccaag gtgcaaacca gcctcattcc agcttcaggg tcaatgactt 750

 actagctcag agggaaatgt ataaatattt aagtacatac ctactatctg 800

 tacagagtga ctctcattac ccagagaact gctgtaaaat attatttatt 850

 cacagattac acaaaaccaa tctaaattag tacttttata cattctattt 900

 ggggagtact taaggtgtat gagcaaacaa attgttatcc aggtcactcc 950

 agaactgttg tatacagatt aagaattgat gttggatact aattaaaatc 1000

 attaaagcaa aatcaaaaaa cactttggct agcatttcaa ttatttttta 1050

 aacaggattt cttaaaacaa tccccaaagt agtcttgtaa tttgttcatt 1100

 ttaaggatct atgttactct gaggccaatc aagggggcta acagtctagt 1150

 tggggagcca agatagcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1200

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntg 1250

 aagaatacct gaaacatggc acctgacctc aaaaagctta aaattaggag 1300

 acatagacat gtaagtaaat aactgctata ggcaaatctc agcaactgcc 1350

 acacctgctt gctcctttag cagaacttct ctgattggcc atattctgca 1400

 catagtgacc aactcacctc ttttccctat ctgctttcct tgctatagct 1450

 gagaaaaaag ctgtggccca aaagtttctc ccctgagagg gacaggatca 1500

 gattgtcttt tcaagagttc ccatgtgcaa tacagagctg aagttgaagc 1550

 tgaaaggatt catagagaaa ggccagtata aatcttcagc ataccaaagt 1600

 tatgagaaag gagaaagctt gcaatgcatg tatagaggag gtgctgagga 1650

 gttggtggta gcagcagaca agggaggaga aatggataga atcatggtta 1700

 ttgtcaaggt ggaggatccg tgaactgcaa ctgaagaggg ctagtgacat 1750

 gacccagttc ttagggctgt ctctattcct gaatatttac ttaatataag 1800

 gcaattctta tatagcatta gggt 1824

<210> 5187
<211> 79
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1168-1248
<223> Unknown amino acid

<400> 5187
 Val Gly Gly Thr Leu Ser Pro Leu Ala Leu Ala Asn Lys Ala Glu
   1               5                  10                  15

 Ser Val Val Ser Val Thr Met Pro Gly Ile Tyr Glu Val Leu Lys
                  20                  25                  30

 Asn Gln Asn Thr Glu Gln Asn Leu Leu Gly Asp Glu Leu Leu Ser
                  35                  40                  45

 Phe Ser Leu Gln His His Arg His Ile Thr Ser Thr Tyr Thr His
                  50                  55                  60

 Thr Glu Lys Ile Leu Lys Arg His Asn Asn His Gly Lys Trp Arg
                  65                  70                  75

 Leu Leu Asp Cys


<210> 5188
<211> 3945
<212> DNA
<213> Homo sapien

<400> 5188
 agcggacttt atcggaacgt gcctaagctg ctgcagctgg cacccggttg 50

 cgctcggcga agagggctgg gggcgggaga tgacggtggt cttctccctg 100

 cttggcaccc tgcgagcacc agctcccttc tcctcgccac tccaaggttg 150

 cagacgaagc aggtactgtc ctagatgtta aggacacaac attgagcaaa 200

 aacatgcata gtccctgctt ccgtgacact tgagtgaact gaatgtgcaa 250

 agtccctgtg gcacaaagtc cctggggcca gtgtgtgtgg cgggtgtaga 300

 aggagctaaa gagatctggt tggagttgga gggtgagaga aaatgaattc 350

 taatttacct gcagagaact taaccattgc agtcaatatg accaagactt 400

 tgcctacagc agtaacgcat ggatttaatt ccactaatga cccaccttca 450

 atgtcaatta caaggctttt tccagcctta ctggaatgct ttggcattgt 500

 cctttgtggc tacatagcag gaagggccaa tgtcataaca tcaacccagg 550

 ccaaaggact aggaaatttt gtctccagat ttgcacttcc agctttatta 600

 ttcaaaaaca tggttgtact taatttttcc aatgtggact ggtccttcct 650

 atatagtatc ttaattgcca aagcttctgt atttttcatt gtatgtgtat 700

 taaccttatt ggttgccagt cctgatagtc gatttagcaa agctggacta 750

 ttccctattt ttgctacaca aagtaatgac tttgcattgg gataccctat 800

 agttgaagct ttatatcaaa ctacataccc agaatatctc cagtacattt 850

 atttggtggc accaatatct cttatgatgt taaaccctat agggtttatt 900

 ttctgtgaaa tccaaaagtg ggaagacact caaaatgctt ctcaaaataa 950

 aataaaaatt gtgggactcg gactcctgcg tgtattacag aacccaatag 1000

 tatttatggt cttcattggc atcgccttca attttattct tgatcgaaag 1050

 gtacctgtat atgtcgaaaa ttttcttgat ggacttggaa attctttttc 1100

 tggatcagcc ctattttatc ttggtctcac gatggtggga aaaataaaga 1150

 gactgaagaa gtcggcattt gtagtactaa ttcttctcat cacagctaaa 1200

 cttctggtgc tgccacttct gtgcagagaa atggtggaac tcttggacaa 1250

 gggcgacagt gtggtgaacc atacaagttt atcaaattat gcatttctgt 1300

 atggtgtatt tcctgtagca ccaggagtgg ctatctttgc aacacaattc 1350

 aacatggaag tagaaattat aacctcaggg atggtgataa gcacatttgt 1400

 gtctgctccc atcatgtacg tttctgcctg gttactgacc tttcccacta 1450

 tggaccctaa gccattggca tatgccatcc agaatgttag ttttgatata 1500

 agtattgtca gcctgatctc cttgatctgg tctctggcta ttcttctttt 1550

 gagtaagaaa tataaacagc ttcctcatat gcttacaact aatttactca 1600

 ttgctcagtc tattgtctgt gctggaatga tgatatggaa ttttgttaaa 1650

 gaaaaaaatt ttgttggaca aattttggtg tttgttctat tgtacagctc 1700

 cctctatagc acctacctgt ggacaggcct tctagcaatt tctttgtttc 1750

 ttttgaaaaa gcgagagagg gtacaaattc ctgttggaat aatcataata 1800

 tctggctggg gaattcctgc tctccttgtt ggtgttcttt tgataactgg 1850

 aaaacacaat ggagatagca ttgactcagc cttcttttat ggaaaagaac 1900

 agatgatcac cacagcagtc accctgttct gcagcatcct gatagctggc 1950

 atatccctca tgtgcatgaa ccagactgcc caagcaggag gctatgaagg 2000

 tttcgatcag tctcagagcc acaaagtggt ggagcctgga aatactgctt 2050

 ttgaggagag tccagcacca gtaaatgaac cagaactttt tacaagctct 2100

 attccagaaa caagttgctg ctcctgctcc atgggaaatg gtgaattaca 2150

 ctgcccatca atagagccaa tagcaaacac aagcaccagt gagcctgtga 2200

 ttccttcgtt tgagaaaaac aatcattgtg tgagtcgctg taactcccag 2250

 agctgcatat tagcccagga agaagaacag tatctacaga gtggagacca 2300

 gcaactgacc cgacatgtgt tgctgtgttt acttctcatc attggcctgt 2350

 tcgctaatct ttacagttgt ttatggtggc tattcaacca agagcctgga 2400

 agactttatg ttgagttaca gtttttctgt gccgtgttta actttggtca 2450

 gggatttatt tcatttggaa tctttggatt agataaacat ttaatcatcc 2500

 tgcctttcaa aagaagactt gaattcctat ggaacaataa agacacagca 2550

 gaaaacaggg attctcctgt ttcagaggaa ataaaaatga cctgtcaaca 2600

 atttatccat tatcaccgtg acctctgtat ccgaaacatt gtcaaagaaa 2650

 gaaggtgtgg tgcaaagact tctgctggaa ctttctgtgg ctgtgacctg 2700

 gtgagctggc taattgaagt cggccttgcc tccgaccgtg gtgaagctgt 2750

 gatatacgga gacaggctgg tacaaggggg agtcatccaa catattacca 2800

 atgagtatga attccgggat gagtacttgt tttacagatt tcttcaaaag 2850

 agtcctgaac agagtcctcc tgctattaat gcaaacactc tccaacagga 2900

 aagatataaa gaaattgagc attcatcccc accctcacat tcccctaaga 2950

 cctaaattat gcaggggaga accctacatg gaatcatatt ctagccgcgt 3000

 attcattagt ttttagctgg gtgaccttgg gcaagttaac agaggcaacc 3050

 tctctgagcc tcagttgtct cttctgtaaa atgtgaaaag atgtgctccc 3100

 accacatgcg cagggtctgt gattttacat gtatgtaaaa cacataggaa 3150

 gctgacttag gaaaaagaga aaaccaaatt aaagttctga taatgaatat 3200

 aatatagtca tcctttagta cccaagggga ttggttccag gactcctgaa 3250

 gatcccaaaa tctgaggata ctcaagtccc ttatataaaa tggtgtaggc 3300

 cgggcatggt ggctcacgcc tgtaatccca gtactttggg aggccgagtc 3350

 aggtggatca cctgaggtca ggagttcaag accagcctgg ccaacatggc 3400

 gaaaccccgt ctctactata aaatacaaaa aattagttgg gtgtggtggc 3450

 gggtgcctgt aatcccagct actcaggagg ctgaggcagg agaatcgctt 3500

 gaatctggga ggcagaggtt gctgtgagcc gagatcgtgc cactgcactc 3550

 cagcctgagc aacagagcaa gactctatct caaaaataaa ataaaataaa 3600

 ataaaataaa ataattaata aaatggtgta gtatttgcat ataacctatg 3650

 cacattctcc catatagttt aatcatcttt agatacttat aatgcctaat 3700

 acaatgtaaa tgctatgtaa atagttgttg ttatactgta ttgtttaggg 3750

 aataacaata agaaaaacag tctgtacatg ttcactacag atgcaaccat 3800

 tgttaagcct gactacatct ttttatctgc agttgattga atctatggat 3850

 gtggaacctg tgcatatgga gggtcaactg tactataaat aatacgaata 3900

 tgccaacatt atataatcat tgctttctgc aaaaaaaaaa aaaaa 3945

<210> 5189
<211> 870
<212> PRT
<213> Homo sapien

<400> 5189
 Met Asn Ser Asn Leu Pro Ala Glu Asn Leu Thr Ile Ala Val Asn
   1               5                  10                  15

 Met Thr Lys Thr Leu Pro Thr Ala Val Thr His Gly Phe Asn Ser
                  20                  25                  30

 Thr Asn Asp Pro Pro Ser Met Ser Ile Thr Arg Leu Phe Pro Ala
                  35                  40                  45

 Leu Leu Glu Cys Phe Gly Ile Val Leu Cys Gly Tyr Ile Ala Gly
                  50                  55                  60

 Arg Ala Asn Val Ile Thr Ser Thr Gln Ala Lys Gly Leu Gly Asn
                  65                  70                  75

 Phe Val Ser Arg Phe Ala Leu Pro Ala Leu Leu Phe Lys Asn Met
                  80                  85                  90

 Val Val Leu Asn Phe Ser Asn Val Asp Trp Ser Phe Leu Tyr Ser
                  95                 100                 105

 Ile Leu Ile Ala Lys Ala Ser Val Phe Phe Ile Val Cys Val Leu
                 110                 115                 120

 Thr Leu Leu Val Ala Ser Pro Asp Ser Arg Phe Ser Lys Ala Gly
                 125                 130                 135

 Leu Phe Pro Ile Phe Ala Thr Gln Ser Asn Asp Phe Ala Leu Gly
                 140                 145                 150

 Tyr Pro Ile Val Glu Ala Leu Tyr Gln Thr Thr Tyr Pro Glu Tyr
                 155                 160                 165

 Leu Gln Tyr Ile Tyr Leu Val Ala Pro Ile Ser Leu Met Met Leu
                 170                 175                 180

 Asn Pro Ile Gly Phe Ile Phe Cys Glu Ile Gln Lys Trp Glu Asp
                 185                 190                 195

 Thr Gln Asn Ala Ser Gln Asn Lys Ile Lys Ile Val Gly Leu Gly
                 200                 205                 210

 Leu Leu Arg Val Leu Gln Asn Pro Ile Val Phe Met Val Phe Ile
                 215                 220                 225

 Gly Ile Ala Phe Asn Phe Ile Leu Asp Arg Lys Val Pro Val Tyr
                 230                 235                 240

 Val Glu Asn Phe Leu Asp Gly Leu Gly Asn Ser Phe Ser Gly Ser
                 245                 250                 255

 Ala Leu Phe Tyr Leu Gly Leu Thr Met Val Gly Lys Ile Lys Arg
                 260                 265                 270

 Leu Lys Lys Ser Ala Phe Val Val Leu Ile Leu Leu Ile Thr Ala
                 275                 280                 285

 Lys Leu Leu Val Leu Pro Leu Leu Cys Arg Glu Met Val Glu Leu
                 290                 295                 300

 Leu Asp Lys Gly Asp Ser Val Val Asn His Thr Ser Leu Ser Asn
                 305                 310                 315

 Tyr Ala Phe Leu Tyr Gly Val Phe Pro Val Ala Pro Gly Val Ala
                 320                 325                 330

 Ile Phe Ala Thr Gln Phe Asn Met Glu Val Glu Ile Ile Thr Ser
                 335                 340                 345

 Gly Met Val Ile Ser Thr Phe Val Ser Ala Pro Ile Met Tyr Val
                 350                 355                 360

 Ser Ala Trp Leu Leu Thr Phe Pro Thr Met Asp Pro Lys Pro Leu
                 365                 370                 375

 Ala Tyr Ala Ile Gln Asn Val Ser Phe Asp Ile Ser Ile Val Ser
                 380                 385                 390

 Leu Ile Ser Leu Ile Trp Ser Leu Ala Ile Leu Leu Leu Ser Lys
                 395                 400                 405

 Lys Tyr Lys Gln Leu Pro His Met Leu Thr Thr Asn Leu Leu Ile
                 410                 415                 420

 Ala Gln Ser Ile Val Cys Ala Gly Met Met Ile Trp Asn Phe Val
                 425                 430                 435

 Lys Glu Lys Asn Phe Val Gly Gln Ile Leu Val Phe Val Leu Leu
                 440                 445                 450

 Tyr Ser Ser Leu Tyr Ser Thr Tyr Leu Trp Thr Gly Leu Leu Ala
                 455                 460                 465

 Ile Ser Leu Phe Leu Leu Lys Lys Arg Glu Arg Val Gln Ile Pro
                 470                 475                 480

 Val Gly Ile Ile Ile Ile Ser Gly Trp Gly Ile Pro Ala Leu Leu
                 485                 490                 495

 Val Gly Val Leu Leu Ile Thr Gly Lys His Asn Gly Asp Ser Ile
                 500                 505                 510

 Asp Ser Ala Phe Phe Tyr Gly Lys Glu Gln Met Ile Thr Thr Ala
                 515                 520                 525

 Val Thr Leu Phe Cys Ser Ile Leu Ile Ala Gly Ile Ser Leu Met
                 530                 535                 540

 Cys Met Asn Gln Thr Ala Gln Ala Gly Gly Tyr Glu Gly Phe Asp
                 545                 550                 555

 Gln Ser Gln Ser His Lys Val Val Glu Pro Gly Asn Thr Ala Phe
                 560                 565                 570

 Glu Glu Ser Pro Ala Pro Val Asn Glu Pro Glu Leu Phe Thr Ser
                 575                 580                 585

 Ser Ile Pro Glu Thr Ser Cys Cys Ser Cys Ser Met Gly Asn Gly
                 590                 595                 600

 Glu Leu His Cys Pro Ser Ile Glu Pro Ile Ala Asn Thr Ser Thr
                 605                 610                 615

 Ser Glu Pro Val Ile Pro Ser Phe Glu Lys Asn Asn His Cys Val
                 620                 625                 630

 Ser Arg Cys Asn Ser Gln Ser Cys Ile Leu Ala Gln Glu Glu Glu
                 635                 640                 645

 Gln Tyr Leu Gln Ser Gly Asp Gln Gln Leu Thr Arg His Val Leu
                 650                 655                 660

 Leu Cys Leu Leu Leu Ile Ile Gly Leu Phe Ala Asn Leu Tyr Ser
                 665                 670                 675

 Cys Leu Trp Trp Leu Phe Asn Gln Glu Pro Gly Arg Leu Tyr Val
                 680                 685                 690

 Glu Leu Gln Phe Phe Cys Ala Val Phe Asn Phe Gly Gln Gly Phe
                 695                 700                 705

 Ile Ser Phe Gly Ile Phe Gly Leu Asp Lys His Leu Ile Ile Leu
                 710                 715                 720

 Pro Phe Lys Arg Arg Leu Glu Phe Leu Trp Asn Asn Lys Asp Thr
                 725                 730                 735

 Ala Glu Asn Arg Asp Ser Pro Val Ser Glu Glu Ile Lys Met Thr
                 740                 745                 750

 Cys Gln Gln Phe Ile His Tyr His Arg Asp Leu Cys Ile Arg Asn
                 755                 760                 765

 Ile Val Lys Glu Arg Arg Cys Gly Ala Lys Thr Ser Ala Gly Thr
                 770                 775                 780

 Phe Cys Gly Cys Asp Leu Val Ser Trp Leu Ile Glu Val Gly Leu
                 785                 790                 795

 Ala Ser Asp Arg Gly Glu Ala Val Ile Tyr Gly Asp Arg Leu Val
                 800                 805                 810

 Gln Gly Gly Val Ile Gln His Ile Thr Asn Glu Tyr Glu Phe Arg
                 815                 820                 825

 Asp Glu Tyr Leu Phe Tyr Arg Phe Leu Gln Lys Ser Pro Glu Gln
                 830                 835                 840

 Ser Pro Pro Ala Ile Asn Ala Asn Thr Leu Gln Gln Glu Arg Tyr
                 845                 850                 855

 Lys Glu Ile Glu His Ser Ser Pro Pro Ser His Ser Pro Lys Thr
                 860                 865                 870

<210> 5190
<211> 374
<212> DNA
<213> Homo sapien

<400> 5190
 agctgttatt gcccttagtt tacagatgag aaagttgaga cttaaagcca 50

 ttaagaattt tgtggtagca aagaaggatc ctgtatttgg taaatttggg 100

 tgtaattatg agtttaatgt atgccttttt ggcagtatcc tttctggctt 150

 catcatgcta tatccccatt gtccacaaca ttgactggtg cttagtaagg 200

 tgctcaagga cgcatcaaat gaatgaacaa agactagaga cagagttgcc 250

 tggccttatt ctttaaatac ccacactata ggactgcaac aaaatacaga 300

 gccctagtga ttagaagact tcaaaagtgt gttttctttt tccaggtgca 350

 tgcctttgat ttcttgagat gatg 374

<210> 5191
<211> 60
<212> PRT
<213> Homo sapien

<400> 5191
 Ala Val Ile Ala Leu Ser Leu Gln Met Arg Lys Leu Arg Leu Lys
   1               5                  10                  15

 Ala Ile Lys Asn Phe Val Val Ala Lys Lys Asp Pro Val Phe Gly
                  20                  25                  30

 Lys Phe Gly Cys Asn Tyr Glu Phe Asn Val Cys Leu Phe Gly Ser
                  35                  40                  45

 Ile Leu Ser Gly Phe Ile Met Leu Tyr Pro His Cys Pro Gln His
                  50                  55                  60

<210> 5192
<211> 1143
<212> DNA
<213> Homo sapien

<400> 5192
 aaggcagttt gcatctgtac atgtgaatgt ttgactgtac cattgactgt 50

 tatggaagtt cagcgttgta tgtctctctc tacactgtgg tgcacttaac 100

 ttgtggaatt tttatactaa aaatgtagaa taaagactat tttgaagatt 150

 tgaataaagt gatgaaggtg actgatgcac ctggggtcat atagaaggtc 200

 tgtggctctt ctgtgttaaa caagtgagct aggtacaagg tagtaaggat 250

 agcatacacc ataggttcta gtatcgagta agctccactt gtcttgcttt 300

 gccgtattct atctttacaa ttcaaaaata tctaaaatga aggacctgat 350

 agatttcaaa gcaactattt ggtagcgaat catgtttata aaacaaacca 400

 aagctcattt taagtctatt attggaaagt gccatcagga ttaagatgtt 450

 ctgttccatg gctatgactg aaatcaatgt tgggaagcta atgttttcat 500

 gactagcatt ctctctctgt tcaagcaccg acaactcctt ttggctgggc 550

 cttgcctctt ttggccacag accttctata tgaccccagg tgcatcagtc 600

 acagttgctc agaaccctgc tcagtgataa acatcttact aaagctgggt 650

 caatcagggt cactctctgg aatgttaaac atgaagcctg agacaagatc 700

 tctcttttat ctggggtccc caaaggcaat gctgtacact tggagctgcc 750

 tgctgccctg caactactcc catttaccaa ttatctggaa gaaccagtct 800

 actatagaag acaacgaggc caacacacaa aaacacagta aaagtatgga 850

 caaattagtg ggatccctga aatctattcc aactatgtgc ttccaagtca 900

 catgactcaa taaatgcttc agctggttga gttgtgcttg gcgttcacta 950

 ccaggagagt tctgattaat aaaaactcat tccatcaatt aataatttag 1000

 tagctctctt tcaacctgag ccaaattcaa gcataagcta aaggataagc 1050

 agtgacccat ggccaatttc ctatgtcata cacttgccat tagtgacgta 1100

 agttaagcca ttcttcaaaa cattaaacag ccttcaagaa caa 1143

<210> 5193
<211> 32
<212> PRT
<213> Homo sapien

<400> 5193
 Lys Ala Val Cys Ile Cys Thr Cys Glu Cys Leu Thr Val Pro Leu
   1               5                  10                  15

 Thr Val Met Glu Val Gln Arg Cys Met Ser Leu Ser Thr Leu Trp
                  20                  25                  30

 Cys Thr


<210> 5194
<211> 1700
<212> DNA
<213> Homo sapien

<400> 5194
 gcatcctgga tgaacatacg tatgcacagg ttatttttta aggacaattc 50

 tttccataag gtctgtaccc ggtacttgaa acaggtgttc atgaaaaaaa 100

 tgcacaaatc ctgcctgccc ggaataattc atgaagaagg ggctggatcc 150

 gtgggtcaga gaacacagga ccagtttgcc atcccaaggc cgaaggatta 200

 tagaacacat gtgctcctta aagaaaaaca ctgtgcatgg agataacagt 250

 catcaaacat ggaaaccttt gagttgaatt cgagggacaa acgtcctgaa 300

 gaatgggaag aaaggaggtt ctgaaggcac agattccagt accatgccag 350

 aggttgagga cactggtgct tgaagggaaa ctggcacact ctggagcccc 400

 aagaagagct ggagctggag gcatgcggcc cacgaagggt agaagtacca 450

 gccatgacca agagcccttc acatcatctg gcaatccatc cagaacccac 500

 tgaatggagg acagcacagc gaggtctttc tcattttgta actgcaaagc 550

 tggaacaaga gccagagaag ccaaagaagc agtacaagtc caacagcttt 600

 tagaataacc ctgagaaaat ggttgaattt tgaccagttt tgcaattgga 650

 tactatgaga agagaccttc cctcctgcac tggatttcat catcatacct 700

 ggaggccatt cctcatggga ctttggccat ctcatatcca cctttaagca 750

 tgttattccc atttcagctg tggtagctct gggtatcctt ccctaggaga 800

 aaatattaat cttttctccc tctgagttct ggattaaact gtcttatctg 850

 aaactgggtc actttaggct agaagcacca ctagacattc ctgttctcag 900

 aagttgccaa gttcatgtca tatctgtttc attgttaacg ggatccactt 950

 ctgcaagagg ctgcctggcc agatcagtgt gtctcctggt cagctccttg 1000

 atgcccttct cctctcccct gcccaatccc agctgagact tgcactgtgg 1050

 tgactctgtc ccctcctggt gctttgactg gatgtgtgag agaaagtatg 1100

 gtctgtggca ctgacatctt tgtgtgtttg gaggtgactg gaacacggat 1150

 ccacccctgg aggaaggtgg ccgtgaagga ggccagcctc agctcagcgt 1200

 tctactctca tcgctcttac tcccgccttt ttagtgcctg ccctactcca 1250

 ggataattgt gcttttcttt tttcagttaa atgttagcat tgctattttt 1300

 cattattgca aagcagcaca tgcttgttac aaaaactttg gaagtgtaga 1350

 caaataaaaa gaagaaaaag ctacttccaa atcctactta ccccaaagac 1400

 aagatgatca tttagtcata tagtatcata catatataat atgtacacat 1450

 atattttaat gtaagtgtag tgtcacaata tcatgtatag tctttcataa 1500

 aacacgttgg cacttaatat cttatatgaa caactttcta gagcaacaag 1550

 cttagtttac agcaattgta atgtaagagt actcatttac atagctacag 1600

 catcctttgt ttacctcatc tcttatggtt tgatgtttag gttgtttcca 1650

 acttttctcc acctaaacag cattaataaa tgtggtttta gtttcctctt 1700

<210> 5195
<211> 81
<212> PRT
<213> Homo sapien

<400> 5195
 Ala Ser Trp Met Asn Ile Arg Met His Arg Leu Phe Phe Lys Asp
   1               5                  10                  15

 Asn Ser Phe His Lys Val Cys Thr Arg Tyr Leu Lys Gln Val Phe
                  20                  25                  30

 Met Lys Lys Met His Lys Ser Cys Leu Pro Gly Ile Ile His Glu
                  35                  40                  45

 Glu Gly Ala Gly Ser Val Gly Gln Arg Thr Gln Asp Gln Phe Ala
                  50                  55                  60

 Ile Pro Arg Pro Lys Asp Tyr Arg Thr His Val Leu Leu Lys Glu
                  65                  70                  75

 Lys His Cys Ala Trp Arg
                  80

<210> 5196
<211> 652
<212> DNA
<213> Homo sapien

<400> 5196
 aaaaagaaag accctagctg tctgaatgat ctgagctaag tccccagacg 50

 tgcaagtgtg gccatcctag accactgagc tccagccaag ccagcttgca 100

 tcagaagaac tgtccagaaa actcacagaa tcataagaaa taatgcagcg 150

 cagcttaact tggactcacc acctatcaag tgctcgacag ccacgtgtgc 200

 agtggttcct acgtggagca gcatacatcc agagatgcaa atattaatga 250

 ggacagtgct agtaacagag ttgctgagca atctatgtcc ccttgtaaga 300

 accagtgccc caggggaaga aacagaactc cacaaggtag cagtgtgggt 350

 gtagtacccg catgtgccca tgttatggga atgtagatgg ggagtgacca 400

 ccgccaacag aagtgtggcc atcttgcccg agatgcctga ggacctccta 450

 tttttagatg ctgctgccca aggcctgtat ttcatgctat ggcttttgtc 500

 atttgaatta tcagtagctg tctcggagct attacgcttc actgggccct 550

 ggaggatatt gtcttataca gtccactggg ttttggatat gcagtctgtg 600

 cctttcattg ccttcctgga aaataataac taaactcttc ctcaccaaaa 650

 aa 652

<210> 5197
<211> 89
<212> PRT
<213> Homo sapien

<400> 5197
 Ala Lys Pro Ala Cys Ile Arg Arg Thr Val Gln Lys Thr His Arg
   1               5                  10                  15

 Ile Ile Arg Asn Asn Ala Ala Gln Leu Asn Leu Asp Ser Pro Pro
                  20                  25                  30

 Ile Lys Cys Ser Thr Ala Thr Cys Ala Val Val Pro Thr Trp Ser
                  35                  40                  45

 Ser Ile His Pro Glu Met Gln Ile Leu Met Arg Thr Val Leu Val
                  50                  55                  60

 Thr Glu Leu Leu Ser Asn Leu Cys Pro Leu Val Arg Thr Ser Ala
                  65                  70                  75

 Pro Gly Glu Glu Thr Glu Leu His Lys Val Ala Val Trp Val
                  80                  85

<210> 5198
<211> 4994
<212> DNA
<213> Homo sapien

<400> 5198
 ccgcagcgct cggctggctg cagcggcacc gcgggttgcg cggccgggga 50

 tgctccagcg ggcgcgatgg cccccgccat gcagccggcc gagatccaat 100

 ttgcccagcg gctggcgtcc agcgagaagg gcatccggga ccgagcggtg 150

 aagaagctgc gccagtacat cagcgtgaag acgcagaggg agacaggagg 200

 tttcagtcag gaagaacttc tacaggaaga gctcgccaac accattgcac 250

 agctagtcca tgctgttaac aactcagcgg ctcaacacct gttcattcag 300

 accttttggc aaaccatgaa tcgagaatgg aaaggaatag acaggctacg 350

 cctggacaaa tactatatgc tgattcgtct ggtcctgagg cagtcctttg 400

 aagtcttgaa gcgaaatggc tgggaagaaa gccgaatcaa ggttttcttg 450

 gatgtcctga tgaaggaggt cctgtgtcct gagagtcagt ctcctaatgg 500

 agtgagattc cacttcattg atatttacct ggatgaactc tccaaagtcg 550

 gggggaagga gcttttagca gatcagaatc tcaagtttat cgatccattc 600

 tgcaaaattg ctgcaaagac gaaggaccac accctggtac agaccatagc 650

 tcggggtgtc ttcgaagcta tcgtagatca gtctcctttt gtgcctgaag 700

 agacgatgga ggaacagaag acaaaagtgg gtgatggtga cctctctgct 750

 gaggagatac ctgaaaatga ggtatccttg agaagagctg tcagtaaaaa 800

 gaagacagca ctgggcaaaa accattccag aaaagatgga ctcagtgatg 850

 aaagaggaag agatgactgt ggaacctttg aggacacagg gccccttctc 900

 cagtttgact ataaggctgt tgctgatcga ctcctggaaa tgaccagcag 950

 gaagaacacg ccccacttca acaggaagcg cctctccaaa ctcatcaaga 1000

 aattccaaga cctttctgaa ggaagcagta tatctcaact cagttttgcg 1050

 gaggacattt ctgctgatga agatgaccaa atcctcagtc aaggaaagca 1100

 taagaagaaa ggaaataaac ttttagagaa aactaacttg gaaaaggaga 1150

 aaggaagcag agtcttttgt gtagaggaag aggacagtga aagcagtctt 1200

 caaaagagaa gaaggaagaa gaagaagaag caccacctgc agcctgaaaa 1250

 tccaggccca gggggtgcag ccccgtccct ggaacagaac cggggcaggg 1300

 agcccgaggc ctctgggccg aaagccctga aggcacgtgt ggccgagcca 1350

 ggtgcagagg ccacgtccag cactggggag gagagtggct ccgagcatcc 1400

 tccagccgtc cccatgcaca ataaaaggaa acggccacgg aagaagagcc 1450

 cgagggccca cagggaaatg ttggaatcag cagtgttgcc cccagaggac 1500

 atgtctcaga gtggcccgag tggcagtcat cctcagggac ctagagggtc 1550

 cccgacaggt ggagcccaac tcctaaaaag gaagcggaaa cttggagttg 1600

 tgcccgtcaa tggcagtggc ctgtccacgc cggcctggcc tccattgcag 1650

 caggaaggcc ctcccacagg ccccgcagag ggggcgaaca gccacaccac 1700

 gctgccccag cgcaggaggc tgcagaaaaa gaaggcaggg cccggcagcc 1750

 tggagctctg tggcctgccc agccagaaaa cagcaagttt gaaaaagagg 1800

 aagaaaatga gagtgatgtc aaacttggtg gagcacaacg gggtgctgga 1850

 gtccgaagct gggcaacccc aggctctggg aagcagtggg acttgcagtt 1900

 ccctgaagaa gcagaagctg agggcagaga gcgactttgt gaagtttgac 1950

 acccccttct taccaaagcc cctgttcttc agaagagcca agagcagcac 2000

 tgccacccac cctccaggcc ctgccgtcca gctaaacaag acaccatcca 2050

 gctccaagaa agtcaccttt gggctgaaca gaaacatgac tgccgaattc 2100

 aagaagacag acaagagtat cttggtcagt cccacgggcc cttctcgagt 2150

 ggccttcgac cctgaacaga agcccctcca cggggtgctg aagaccccca 2200

 ccagctcacc tgccagctca cccctggtgg ccaagaagcc cctgaccacc 2250

 acaccaagga gaaggcccag ggctatggat ttcttctgag gagcagcaga 2300

 gtcccttgta aaagactgct tttgtacaga atgcgctata aattatacct 2350

 ttaagaatgt ggggcctttt ttatgatttt gtaagttccc ataagttgtg 2400

 tgcacgaggt tctgagagtg cccgcaggct gctgcgtcct ggcccctctg 2450

 tagtggctgc gggcgtcttg gttgaatctt ttgctacaaa ccatgtttgc 2500

 gtttgagctc tccaggattt tacatttttg ggtaacctca gtgattccca 2550

 ttggtgtagg aaatgagacc ctctctgaag ctgaggagag cacgttgatc 2600

 tgaactttaa atcaatcagt gctgctggca caatgaaagg tggaactgca 2650

 cttgtgttga gctctcagtt ctgcggaatt tggtactcat taccgtattc 2700

 gccgtactaa gttggtttct gttagtctta acagtctgtt ttcttttaaa 2750

 agcatgtagg gcttcattgc catgttctgt gggtgtttgg caggttaccg 2800

 atggggaaga ttcttgtcac agaatcagca ataccatagt ttttctacat 2850

 gtgctcagct gggggtgtgg acaggtaggg gtggggaaag aagaggctct 2900

 gcgttctggg ggctttttct tctcctcccc ctacccggtt tccctccctg 2950

 ttttcctacc tctacggcaa gcccaaagtg tcttcccggg agcccagcgc 3000

 agcccccggc tcttacccag gaccccgccc cgtgctgagc cttctgctga 3050

 ggtccttgcg tggagcacac tcattcctcc aagcccttgc gctcccgttt 3100

 ctctctctct ccgtccacgt tccagccgag tcactgcctg cctgaccggc 3150

 tccatggcag ctccccatct tccctagagg ctgcctgcgc atctggagcc 3200

 tgcgctccgg ctcagcgacc tttcctctca aatgcggaag cgtgcactta 3250

 cagttcagac cgttctcctg taagttcatt acaaacacgg gcggaaggca 3300

 ctcaggcttt cgttggagaa acagaaataa ggccttcttt tgagcagcga 3350

 ttgctggatc attgatctgt ttgaggaagt gtctgacctg ggcctgagag 3400

 ctggagaagg tgcagattca aagtgagcgg ctcctgagga gagccgccaa 3450

 ggctgctcgc cttctccgtg gcttccgcag ctaccgtctg cacggtgaga 3500

 gggcacgggc acacggttcg ggctggcgtg cagctctccc agccagccac 3550

 gctctgctca ggcctggaag tgaaagccgc ctccttcccg ttatgccccc 3600

 catacaggag cctcggtttt tcagcaaaac gcggccagtc cccttctcca 3650

 ctgctgcctc ccagcagagg gccccaggat ctccaaggtc ccagctatgg 3700

 ctttggacaa cgtggcttcg gcccctgggg ttgcagagct tgcattgggt 3750

 ttacctcggt ctcattcatt catggagcca agggtggggt ttcacctgcg 3800

 aacatcagac tgacttgctg gcgtcaagag cagttgactc actgatgaag 3850

 gccctggtga ggagaaagca ctctgttctt cgcctactct gtaatcgttt 3900

 tgtcataatg agccatgaaa aaagtaatga acttgtgctg ttaatcgtca 3950

 ctgtaatgag aagtcttacg tacaacatag ctgtggtggc tgcgtggttt 4000

 aatggctgca ttagatagga tcctcacatc ccattcagaa ccaaaactga 4050

 tacagtgaaa caattaaggt gagcaaatag ttttaacttt tctttttttt 4100

 ttaagtttca ttcttcctag aatatttttc taacaatttt tatttcagct 4150

 ttaaagatgg gtcatatagc caaacgggcc atataatcca acattgttga 4200

 gatgtcttag gacatctaag gcaaaactgg cacatttgtt ctgcagacta 4250

 ttgcaggaat gttttttcct agcatttcta tattatctgt ccattctgag 4300

 gaaccagtga atgtcctata aatgcacctc ctgtcaaaac catgcctgag 4350

 aggtcccggc tgggagtgac agggtgcttc ttagattcta ttggtccttc 4400

 tctcattctc cgaacttact cctttttatg ggtaagtcaa ctaggtttac 4450

 agtcccttat ttttaatgcc taagttttga cagcaggaag aaaacaattt 4500

 tttaaaaatt ctcattacat agacgcacaa gaatatgtca cataaagaaa 4550

 atgtgtttag aatactggtt ttctatttac gcatgatatt ttcctaagta 4600

 aaattgccaa gtggacttgg aagtccagaa aggaaaataa tttaaattaa 4650

 tgctggtgat cttaacaata ttttgtaaaa tgatgcttcc cccttctcca 4700

 tggtctagtc aattttgtac aattaggtat ctgactttac aagtttgtta 4750

 tcctttctaa tttttactga actgaaagca caaagaagac tacacagaaa 4800

 atctggaaac agttgcaggt gttgggagga agatgaaatc gagctgtctt 4850

 ttaacttttg tatgtgtttt atcagaattt gctggactat gctggcaagg 4900

 actttgttta cgatcaaatt gtactagtgt ctgcagggtt tgtcagtact 4950

 cgtcaaagcc aagtccaatt aaaaaaaaaa agtctttgcc ctcc 4994

<210> 5199
<211> 762
<212> PRT
<213> Homo sapien

<400> 5199
 Pro Gln Arg Ser Ala Gly Cys Ser Gly Thr Ala Gly Cys Ala Ala
   1               5                  10                  15

 Gly Asp Ala Pro Ala Gly Ala Met Ala Pro Ala Met Gln Pro Ala
                  20                  25                  30

 Glu Ile Gln Phe Ala Gln Arg Leu Ala Ser Ser Glu Lys Gly Ile
                  35                  40                  45

 Arg Asp Arg Ala Val Lys Lys Leu Arg Gln Tyr Ile Ser Val Lys
                  50                  55                  60

 Thr Gln Arg Glu Thr Gly Gly Phe Ser Gln Glu Glu Leu Leu Gln
                  65                  70                  75

 Glu Glu Leu Ala Asn Thr Ile Ala Gln Leu Val His Ala Val Asn
                  80                  85                  90

 Asn Ser Ala Ala Gln His Leu Phe Ile Gln Thr Phe Trp Gln Thr
                  95                 100                 105

 Met Asn Arg Glu Trp Lys Gly Ile Asp Arg Leu Arg Leu Asp Lys
                 110                 115                 120

 Tyr Tyr Met Leu Ile Arg Leu Val Leu Arg Gln Ser Phe Glu Val
                 125                 130                 135

 Leu Lys Arg Asn Gly Trp Glu Glu Ser Arg Ile Lys Val Phe Leu
                 140                 145                 150

 Asp Val Leu Met Lys Glu Val Leu Cys Pro Glu Ser Gln Ser Pro
                 155                 160                 165

 Asn Gly Val Arg Phe His Phe Ile Asp Ile Tyr Leu Asp Glu Leu
                 170                 175                 180

 Ser Lys Val Gly Gly Lys Glu Leu Leu Ala Asp Gln Asn Leu Lys
                 185                 190                 195

 Phe Ile Asp Pro Phe Cys Lys Ile Ala Ala Lys Thr Lys Asp His
                 200                 205                 210

 Thr Leu Val Gln Thr Ile Ala Arg Gly Val Phe Glu Ala Ile Val
                 215                 220                 225

 Asp Gln Ser Pro Phe Val Pro Glu Glu Thr Met Glu Glu Gln Lys
                 230                 235                 240

 Thr Lys Val Gly Asp Gly Asp Leu Ser Ala Glu Glu Ile Pro Glu
                 245                 250                 255

 Asn Glu Val Ser Leu Arg Arg Ala Val Ser Lys Lys Lys Thr Ala
                 260                 265                 270

 Leu Gly Lys Asn His Ser Arg Lys Asp Gly Leu Ser Asp Glu Arg
                 275                 280                 285

 Gly Arg Asp Asp Cys Gly Thr Phe Glu Asp Thr Gly Pro Leu Leu
                 290                 295                 300

 Gln Phe Asp Tyr Lys Ala Val Ala Asp Arg Leu Leu Glu Met Thr
                 305                 310                 315

 Ser Arg Lys Asn Thr Pro His Phe Asn Arg Lys Arg Leu Ser Lys
                 320                 325                 330

 Leu Ile Lys Lys Phe Gln Asp Leu Ser Glu Gly Ser Ser Ile Ser
                 335                 340                 345

 Gln Leu Ser Phe Ala Glu Asp Ile Ser Ala Asp Glu Asp Asp Gln
                 350                 355                 360

 Ile Leu Ser Gln Gly Lys His Lys Lys Lys Gly Asn Lys Leu Leu
                 365                 370                 375

 Glu Lys Thr Asn Leu Glu Lys Glu Lys Gly Ser Arg Val Phe Cys
                 380                 385                 390

 Val Glu Glu Glu Asp Ser Glu Ser Ser Leu Gln Lys Arg Arg Arg
                 395                 400                 405

 Lys Lys Lys Lys Lys His His Leu Gln Pro Glu Asn Pro Gly Pro
                 410                 415                 420

 Gly Gly Ala Ala Pro Ser Leu Glu Gln Asn Arg Gly Arg Glu Pro
                 425                 430                 435

 Glu Ala Ser Gly Pro Lys Ala Leu Lys Ala Arg Val Ala Glu Pro
                 440                 445                 450

 Gly Ala Glu Ala Thr Ser Ser Thr Gly Glu Glu Ser Gly Ser Glu
                 455                 460                 465

 His Pro Pro Ala Val Pro Met His Asn Lys Arg Lys Arg Pro Arg
                 470                 475                 480

 Lys Lys Ser Pro Arg Ala His Arg Glu Met Leu Glu Ser Ala Val
                 485                 490                 495

 Leu Pro Pro Glu Asp Met Ser Gln Ser Gly Pro Ser Gly Ser His
                 500                 505                 510

 Pro Gln Gly Pro Arg Gly Ser Pro Thr Gly Gly Ala Gln Leu Leu
                 515                 520                 525

 Lys Arg Lys Arg Lys Leu Gly Val Val Pro Val Asn Gly Ser Gly
                 530                 535                 540

 Leu Ser Thr Pro Ala Trp Pro Pro Leu Gln Gln Glu Gly Pro Pro
                 545                 550                 555

 Thr Gly Pro Ala Glu Gly Ala Asn Ser His Thr Thr Leu Pro Gln
                 560                 565                 570

 Arg Arg Arg Leu Gln Lys Lys Lys Ala Gly Pro Gly Ser Leu Glu
                 575                 580                 585

 Leu Cys Gly Leu Pro Ser Gln Lys Thr Ala Ser Leu Lys Lys Arg
                 590                 595                 600

 Lys Lys Met Arg Val Met Ser Asn Leu Val Glu His Asn Gly Val
                 605                 610                 615

 Leu Glu Ser Glu Ala Gly Gln Pro Gln Ala Leu Gly Ser Ser Gly
                 620                 625                 630

 Thr Cys Ser Ser Leu Lys Lys Gln Lys Leu Arg Ala Glu Ser Asp
                 635                 640                 645

 Phe Val Lys Phe Asp Thr Pro Phe Leu Pro Lys Pro Leu Phe Phe
                 650                 655                 660

 Arg Arg Ala Lys Ser Ser Thr Ala Thr His Pro Pro Gly Pro Ala
                 665                 670                 675

 Val Gln Leu Asn Lys Thr Pro Ser Ser Ser Lys Lys Val Thr Phe
                 680                 685                 690

 Gly Leu Asn Arg Asn Met Thr Ala Glu Phe Lys Lys Thr Asp Lys
                 695                 700                 705

 Ser Ile Leu Val Ser Pro Thr Gly Pro Ser Arg Val Ala Phe Asp
                 710                 715                 720

 Pro Glu Gln Lys Pro Leu His Gly Val Leu Lys Thr Pro Thr Ser
                 725                 730                 735

 Ser Pro Ala Ser Ser Pro Leu Val Ala Lys Lys Pro Leu Thr Thr
                 740                 745                 750

 Thr Pro Arg Arg Arg Pro Arg Ala Met Asp Phe Phe
                 755                 760

<210> 5200
<211> 2427
<212> DNA
<213> Homo sapien

<400> 5200
 cggacgcgtg gggagaggct gtttaccaga acagcataac aagggcaggt 50

 ctgactgcaa ggctgggact gggaggcaga gccgccgcca agggggcctc 100

 ggttaaacac tggtcgttca atcacctgca agacgaagga ggcaaggatg 150

 ctgttggcct gggtacaagc attcctcgtc agcaacatgc tcctagcaga 200

 agcctatgga tctggaggct gtttctggga caacggccac ctgtaccggg 250

 aggaccagac ctcccccgcg ccgggcctcc gctgcctcaa ctggctggac 300

 gcgcagagcg ggctggcctc ggcccccgtg tcgggggccg gcaatcacag 350

 ttactgccga aacccggacg aggacccgcg cgggccctgg tgctacgtca 400

 gtggcgaggc cggcgtccct gagaaacggc cttgcgagga cctgcgctgt 450

 ccagagacca cctcccaggc cctgccagcc ttcacgacag aaatccagga 500

 agcgtctgaa gggccaggtg cagatgaggt gcaggtgttc gctcctgcca 550

 acgccctgcc cgctcggagt gaggcggcag ctgtgcagcc agtgattggg 600

 atcagccagc gggtgcggat gaactccaag gagaaaaagg acctgggaac 650

 tctgggctac gtgctgggca ttaccatgat ggtgatcatc attgccatcg 700

 gagctggcat catcttgggc tactcctaca agagggggaa ggatttgaaa 750

 gaacagcatg atcagaaagt atgtgagagg gagatgcagc gaatcactct 800

 gcccttgtct gccttcacca accccacctg tgagattgtg gatgagaaga 850

 ctgtcgtggt ccacaccagc cagactccag ttgaccctca ggagggcagc 900

 acccccctta tgggccaggc cgggactcct ggggcctgag cccccccagt 950

 gggcaggagc ccatgcagac actggtgcag gacagcccac cctcctacag 1000

 ctaggaggaa ctaccacttt gtgttctggt taaaacccta ccactccccc 1050

 gcttttttgg cgaatcctag taagagtgac agaagcaggt ggccctgtgg 1100

 gctgagggta aggctgggta gggtcctaac agtgctcctt gtccatccct 1150

 tggagcagat tttgtctgtg gatggagaca gtggcagctc ccacagtgat 1200

 gctgctgcta agggcttcca aacattgcct gcacccctgg aactgaacca 1250

 gggatagacg gggagctccc ccaggctcct ctgtgcttta ctaagatggc 1300

 ctcagtctcc actgtgggct tgagtggcat acactgttat tcatggttaa 1350

 ggtaaagcag gtcaagggat ggcattgaaa aaatatattt agtttttaaa 1400

 atatttggga tggaactccc tactgacctc tgagaactgg aaacgagttt 1450

 gtacagaagt cagaactttg ggttgggaat gagatctagg ttgtggctgc 1500

 tggtatgctt cagcttgctg gcaatgatgt gccttgacaa ccgtgggcca 1550

 ggcctgggcc cagggactct tcctgtttca taaggaaagg aagaattgca 1600

 ctgagcattc cacttaggaa gaggatagag aaggatctgc tccgcctttg 1650

 gccacaggag cagaggcaga cctgggatgc cccagtttct cttcagggat 1700

 ggatagtgac ctgtcttcat tttgcacagg taagagagta gttagctaac 1750

 ctatgggaat tatactgtgg ggccttgtga gctgcttcta agaggctaac 1800

 ctggaaacta agctcagagg caaggtaata aagcacttca gggcttgctc 1850

 cccaagtggg cctgatttag caggtggtcc tgcgggcgtc caggtcagca 1900

 ccttcctgta gggcactggg gctagggtca cagcccctaa ctcataaagc 1950

 aatcaaagaa ccattagaaa gggctcatta agccttttgg acacaggacc 2000

 ccagagagga aaaagtgact tgcccaaggt cgtaagcaag ctactggcat 2050

 ggcaagagcc cagcttcctg acggagcgca acatttctcc actgcactgt 2100

 gctagcagct cagcagggcc tctaacctgt gatgtcacac tcaagaggcc 2150

 ttggcagctc ctagccatag agcttccttt ccagaaccct tccactgccc 2200

 aatgtggaga caggggttag tggggctttc tatggagcca tctgctttgg 2250

 ggacctagac ctcaggtggt ctcttggtgt tagtgatgct ggagaagaga 2300

 atattactgg tttctacttt tctataaagg catttctcta tatacatgtt 2350

 ttatatacct cattctgaca cctgcatata gtgtgggaaa ttgctctgca 2400

 tttgacttaa ttaaaaaaaa aaaaaaa 2427

<210> 5201
<211> 263
<212> PRT
<213> Homo sapien

<400> 5201
 Met Leu Leu Ala Trp Val Gln Ala Phe Leu Val Ser Asn Met Leu
   1               5                  10                  15

 Leu Ala Glu Ala Tyr Gly Ser Gly Gly Cys Phe Trp Asp Asn Gly
                  20                  25                  30

 His Leu Tyr Arg Glu Asp Gln Thr Ser Pro Ala Pro Gly Leu Arg
                  35                  40                  45

 Cys Leu Asn Trp Leu Asp Ala Gln Ser Gly Leu Ala Ser Ala Pro
                  50                  55                  60

 Val Ser Gly Ala Gly Asn His Ser Tyr Cys Arg Asn Pro Asp Glu
                  65                  70                  75

 Asp Pro Arg Gly Pro Trp Cys Tyr Val Ser Gly Glu Ala Gly Val
                  80                  85                  90

 Pro Glu Lys Arg Pro Cys Glu Asp Leu Arg Cys Pro Glu Thr Thr
                  95                 100                 105

 Ser Gln Ala Leu Pro Ala Phe Thr Thr Glu Ile Gln Glu Ala Ser
                 110                 115                 120

 Glu Gly Pro Gly Ala Asp Glu Val Gln Val Phe Ala Pro Ala Asn
                 125                 130                 135

 Ala Leu Pro Ala Arg Ser Glu Ala Ala Ala Val Gln Pro Val Ile
                 140                 145                 150

 Gly Ile Ser Gln Arg Val Arg Met Asn Ser Lys Glu Lys Lys Asp
                 155                 160                 165

 Leu Gly Thr Leu Gly Tyr Val Leu Gly Ile Thr Met Met Val Ile
                 170                 175                 180

 Ile Ile Ala Ile Gly Ala Gly Ile Ile Leu Gly Tyr Ser Tyr Lys
                 185                 190                 195

 Arg Gly Lys Asp Leu Lys Glu Gln His Asp Gln Lys Val Cys Glu
                 200                 205                 210

 Arg Glu Met Gln Arg Ile Thr Leu Pro Leu Ser Ala Phe Thr Asn
                 215                 220                 225

 Pro Thr Cys Glu Ile Val Asp Glu Lys Thr Val Val Val His Thr
                 230                 235                 240

 Ser Gln Thr Pro Val Asp Pro Gln Glu Gly Ser Thr Pro Leu Met
                 245                 250                 255

 Gly Gln Ala Gly Thr Pro Gly Ala
                 260

<210> 5202
<211> 1591
<212> DNA
<213> Homo sapien

<400> 5202
 agcctggggc ggccggccag gaaccacccg ttaaggtgtc ttctctttag 50

 ggatggtgag gttggaaaaa ggctcctgta accctcctcc aggatgaacc 100

 acctgccaga agacatggag aacgctctca ccgggagcca gagctcccat 150

 gcttctctgc gcaatatcca ttccatcaac cccacacaac tcatggccag 200

 gattgagtcc tatgaaggaa gggaaaagaa aggcatatct gatgtcagga 250

 ggactttctg tttgtttgtc acctttgacc tcttattcgt aacattactg 300

 tggataatag agttaaatgt gaatggaggc attgagaaca cattagagaa 350

 ggaggtgatg cagtatgact actattcttc atattttgat atatttcttc 400

 tggcagtttt tcgatttaaa gtgttaatac ttgcatatgc tgtgtgcaga 450

 ctgcgccatt ggtgggcaat agcgttgaca acggcagtga ccagtgcctt 500

 tttactagca aaagtgatcc tttcgaagct tttctctcaa ggggcttttg 550

 gctatgtgct gcccatcatt tcattcatcc ttgcctggat tgagacgtgg 600

 ttcctggatt tcaaagtgtt acctcaagaa gcagaagaag aaaacagact 650

 cctgatagtt caggatgctt cagagagggc agcacttata cctggtggtc 700

 tttctgatgg tcagttttat tcccctcctg aatccgaagc aggatctgaa 750

 gaagctgaag aaaaacagga cagtgagaaa ccacttttag aactatgagt 800

 actacttttg ttaaatgtga aaaaccctca cagaaagtca tcgaggcaaa 850

 aagaggcagg cagtggagtc tccctgtcga cagtaaagtt gaaatggtga 900

 cgtccactgc tggctttatt gaacagctaa taaagattta tttattgtaa 950

 tacctcacag acgttgcacc atatccatgc acatttagtt gcctgcctgt 1000

 ggctggtaag gtaatgtcat gattcatcct ctcttcagtg agactgagcc 1050

 tgatgtgtta acaaataggt gaagaaagtc ttgtgctgta ttcctaatca 1100

 aaagacttaa tatattgaag taacactttt ttagtaagca agataccttt 1150

 ttatttcaat tcacagaatg gaattttttt gtttcatgtc tcagatttat 1200

 tttgtatttc ttttttaaca ctctacattt cccttgtttt ttaactcatg 1250

 cacatgtgct ctttgtacag ttttaaaaag tgtaataaaa tctgacatgt 1300

 caatgtggct agttttattt ttcttgtttt gcattatgtg tatggcctga 1350

 agtgttggac ttgcaaaagg ggaagaaagg aattgcgaat acatgtaaaa 1400

 tgtcaccaga catttgtatt atttttatca tgaaatcatg tttttctctg 1450

 attgttctga aatgttctaa atactcttat tttgaatgca caaaatgact 1500

 taaaccattc atatcatgtt tcctttgcgt tcagccaatt tcaattaaaa 1550

 tgaactaaat taaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1591

<210> 5203
<211> 234
<212> PRT
<213> Homo sapien

<400> 5203
 Met Asn His Leu Pro Glu Asp Met Glu Asn Ala Leu Thr Gly Ser
   1               5                  10                  15

 Gln Ser Ser His Ala Ser Leu Arg Asn Ile His Ser Ile Asn Pro
                  20                  25                  30

 Thr Gln Leu Met Ala Arg Ile Glu Ser Tyr Glu Gly Arg Glu Lys
                  35                  40                  45

 Lys Gly Ile Ser Asp Val Arg Arg Thr Phe Cys Leu Phe Val Thr
                  50                  55                  60

 Phe Asp Leu Leu Phe Val Thr Leu Leu Trp Ile Ile Glu Leu Asn
                  65                  70                  75

 Val Asn Gly Gly Ile Glu Asn Thr Leu Glu Lys Glu Val Met Gln
                  80                  85                  90

 Tyr Asp Tyr Tyr Ser Ser Tyr Phe Asp Ile Phe Leu Leu Ala Val
                  95                 100                 105

 Phe Arg Phe Lys Val Leu Ile Leu Ala Tyr Ala Val Cys Arg Leu
                 110                 115                 120

 Arg His Trp Trp Ala Ile Ala Leu Thr Thr Ala Val Thr Ser Ala
                 125                 130                 135

 Phe Leu Leu Ala Lys Val Ile Leu Ser Lys Leu Phe Ser Gln Gly
                 140                 145                 150

 Ala Phe Gly Tyr Val Leu Pro Ile Ile Ser Phe Ile Leu Ala Trp
                 155                 160                 165

 Ile Glu Thr Trp Phe Leu Asp Phe Lys Val Leu Pro Gln Glu Ala
                 170                 175                 180

 Glu Glu Glu Asn Arg Leu Leu Ile Val Gln Asp Ala Ser Glu Arg
                 185                 190                 195

 Ala Ala Leu Ile Pro Gly Gly Leu Ser Asp Gly Gln Phe Tyr Ser
                 200                 205                 210

 Pro Pro Glu Ser Glu Ala Gly Ser Glu Glu Ala Glu Glu Lys Gln
                 215                 220                 225

 Asp Ser Glu Lys Pro Leu Leu Glu Leu
                 230

<210> 5204
<211> 1138
<212> DNA
<213> Homo sapien

<400> 5204
 ccctttaaag ggtgactcgt cccacttgtg ttctctctcc tggtgcagag 50

 ttgcaagcaa gtttatcaga gtatcgccat gaagttcgtc ccctgcctcc 100

 tgctggtgac cttgtcctgc ctggggactt tgggtcaggc cccgaggcaa 150

 aagcaaggaa gcactgggga ggaattccat ttccagactg gagggagaga 200

 ttcctgcact atgcgtccca gcagcttggg gcaaggtgct ggagaagtct 250

 ggcttcgcgt cgactgccgc aacacagacc agacctactg gtgtgagtac 300

 agggggcagc ccagcatgtg ccaggctttt gctgctgacc ccaaacctta 350

 ctggaatcaa gccctgcagg agctgaggcg ccttcaccat gcgtgccagg 400

 gggccccggt gcttaggcca tccgtgtgca gggaggctgg accccaggcc 450

 catatgcagc aggtgacttc cagcctcaag ggcagcccag agcccaacca 500

 gcagcctgag gctgggacgc catctctgag gcccaaggcc acagtgaaac 550

 tcacagaagc aacacagctg ggaaaggact cgatggaaga gctgggaaaa 600

 gccaaaccca ccacccgacc cacagccaaa cctacccagc ctggacccag 650

 gcccggaggg aatgaggaag caaagaagaa ggcctgggaa cattgttgga 700

 aacccttcca ggccctgtgc gcctttctca tcagcttctt ccgagggtga 750

 caggtgaaag acccctacag atctgacctc tccctgacag acaaccatct 800

 ctttttatat tatgccgctt tcaatccaac gttctcacac tggaagaaga 850

 gagtttctaa tcagatgcaa cggcccaaat tcttgatctg cagcttctct 900

 gaagtttgga aaagaaacct tcctttctgg agtttgcaga gttcagcaat 950

 atgataggga acaggtgctg atgggcccaa gagtgacaag catacacaac 1000

 tacttattat ctgtagaagt tttgctttgt tgatctgagc cttctatgaa 1050

 agtttaaata tgtaacgcat tcatgaattt ccagtgttca gtaaatagca 1100

 gctatgtgtg tgcaaaataa aagaatgatt tcagaaat 1138

<210> 5205
<211> 223
<212> PRT
<213> Homo sapien

<400> 5205
 Met Lys Phe Val Pro Cys Leu Leu Leu Val Thr Leu Ser Cys Leu
   1               5                  10                  15

 Gly Thr Leu Gly Gln Ala Pro Arg Gln Lys Gln Gly Ser Thr Gly
                  20                  25                  30

 Glu Glu Phe His Phe Gln Thr Gly Gly Arg Asp Ser Cys Thr Met
                  35                  40                  45

 Arg Pro Ser Ser Leu Gly Gln Gly Ala Gly Glu Val Trp Leu Arg
                  50                  55                  60

 Val Asp Cys Arg Asn Thr Asp Gln Thr Tyr Trp Cys Glu Tyr Arg
                  65                  70                  75

 Gly Gln Pro Ser Met Cys Gln Ala Phe Ala Ala Asp Pro Lys Pro
                  80                  85                  90

 Tyr Trp Asn Gln Ala Leu Gln Glu Leu Arg Arg Leu His His Ala
                  95                 100                 105

 Cys Gln Gly Ala Pro Val Leu Arg Pro Ser Val Cys Arg Glu Ala
                 110                 115                 120

 Gly Pro Gln Ala His Met Gln Gln Val Thr Ser Ser Leu Lys Gly
                 125                 130                 135

 Ser Pro Glu Pro Asn Gln Gln Pro Glu Ala Gly Thr Pro Ser Leu
                 140                 145                 150

 Arg Pro Lys Ala Thr Val Lys Leu Thr Glu Ala Thr Gln Leu Gly
                 155                 160                 165

 Lys Asp Ser Met Glu Glu Leu Gly Lys Ala Lys Pro Thr Thr Arg
                 170                 175                 180

 Pro Thr Ala Lys Pro Thr Gln Pro Gly Pro Arg Pro Gly Gly Asn
                 185                 190                 195

 Glu Glu Ala Lys Lys Lys Ala Trp Glu His Cys Trp Lys Pro Phe
                 200                 205                 210

 Gln Ala Leu Cys Ala Phe Leu Ile Ser Phe Phe Arg Gly
                 215                 220

<210> 5206
<211> 2431
<212> DNA
<213> Homo sapien

<400> 5206
 ctccaggctg tggaaccttt gttctttcac tctttgcaat aaatcttgct 50

 gctgctcact ctttgggtcc acactgcctt tatgagctgt aacactcact 100

 gggaatgtct gcagcttcac tcctgaagcc agcgagacca cgaacccacc 150

 aggaggaaca aacaactcca gacgcgcagc cttaagagct gtaacactca 200

 ccgcgaaggt ctgcagcttc actcctgagc cagccagacc acgaacccac 250

 cagaaggaag aaactccaaa cacatccgaa catcagaagg agcaaactcc 300

 tgacacgcca cctttaagaa ccgtgacact caacgctagg gtccgcggct 350

 tcattcttga agtcagtgag accaagaacc caccaattcc ggacacgcta 400

 attgttgtag atcatcactt caaggtgccc atatctttct agtggaaaaa 450

 ttattctggc ctccgctgca tacaaatcag gcaaccagaa ttctacatat 500

 ataaggcaaa gtaacatcct agacatggct ttagagatcc acatgtcaga 550

 ccccatgtgc ctcatcgaga actttaatga gcagctgaag gttaatcagg 600

 aagctttgga gatcctgtct gccattacgc aacctgtagt tgtggtagcg 650

 attgtgggcc tctatcgcac tggcaaatcc tacctgatga acaagctggc 700

 tgggaagaac aagggcttct ctgttgcatc tacggtgcag tctcacacca 750

 agggaatttg gatatggtgt gtgcctcatc ccaactggcc aaatcacaca 800

 ttagttctgc ttgacaccga gggcctggga gatgtagaga aggctgacaa 850

 caagaatgat atccagatct ttgcactggc actcttactg agcagcacct 900

 ttgtgtacaa tactgtgaac aaaattgatc agggtgctat cgacctactg 950

 cacaatgtga cagaactgac agatctgctc aaggcaagaa actcacccga 1000

 ccttgacagg gttgaagatc ctgctgactc tgcgagcttc ttcccagact 1050

 tagtgtggac tctgagagat ttctgcttag gcctggaaat agatgggcaa 1100

 cttgtcacac cagatgaata cctggagaat tccctaaggc caaagcaagg 1150

 tagtgatcaa agagttcaaa atttcaattt gccccgtctg tgtatacaga 1200

 agttctttcc aaaaaagaaa tgctttatct ttgacttacc tgctcaccaa 1250

 aaaaagcttg cccaacttga aacactgcct gatgatgagc tagagcctga 1300

 atttgtgcaa caagtgacag aattctgttc ctacatcttt agccattcta 1350

 tgaccaagac tcttccaggt ggcatcatgg tcaatggatc tcgtctaaag 1400

 aacctggtgc tgacctatgt caatgccatc agcagtgggg atctgccttg 1450

 catagagaat gcagtcctgg ccttggctca gagagagaac tcagctgcag 1500

 tgcaaaaggc cattgcccac tatgaccagc aaatgggcca gaaagtgcag 1550

 ctgcccatgg aaaccctcca ggagctgctg gacctgcaca ggaccagtga 1600

 gagggaggcc attgaagtct tcatgaaaaa ctctttcaag gatgtagacc 1650

 aaagtttcca gaaagaattg gagactctac tagatgcaaa acagaatgac 1700

 atttgtaaac ggaacctgga agcatcctcg gattattgct cggctttact 1750

 taaggatatt tttggtcctc tagaagaagc agtgaagcag ggaatttatt 1800

 ctaagccagg aggccataat ctcttcattc agaaaacaga agaactgaag 1850

 gcaaagtact atcgggagcc tcggaaagga atacaggctg aagaagttct 1900

 gcagaaatat ttaaagtcca aggagtctgt gagtcatgca atattacaga 1950

 ctgaccaggc tctcacagag acggaaaaaa agaagaaaga ggcacaagtg 2000

 aaagcagaag ctgaaaaggc tgaagcgcaa aggttggcgg cgattcaaag 2050

 gcagaacgag caaatgatgc aggagaggga gagactccat caggaacaag 2100

 tgagacaaat ggagatagcc aaacaaaatt ggctggcaga gcaacagaaa 2150

 atgcaggaac aacagatgca ggaacaggct gcacagctca gcacaacatt 2200

 ccaagctcaa aatagaagcc ttctcagtga gctccagcac gcccagagga 2250

 ctgttaataa cgatgatcca tgtgttttac tctaaagtgc taaatatggg 2300

 agtttccttt ttttactctt tgtcactgat gacacaacag aaaagaaact 2350

 gtagaccttg ggacaatcaa catttaaata aactttataa ttattttttc 2400

 aaactttaaa aaaaaaaaaa aaaaaaaaaa a 2431

<210> 5207
<211> 586
<212> PRT
<213> Homo sapien

<400> 5207
 Met Ala Leu Glu Ile His Met Ser Asp Pro Met Cys Leu Ile Glu
   1               5                  10                  15

 Asn Phe Asn Glu Gln Leu Lys Val Asn Gln Glu Ala Leu Glu Ile
                  20                  25                  30

 Leu Ser Ala Ile Thr Gln Pro Val Val Val Val Ala Ile Val Gly
                  35                  40                  45

 Leu Tyr Arg Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly
                  50                  55                  60

 Lys Asn Lys Gly Phe Ser Val Ala Ser Thr Val Gln Ser His Thr
                  65                  70                  75

 Lys Gly Ile Trp Ile Trp Cys Val Pro His Pro Asn Trp Pro Asn
                  80                  85                  90

 His Thr Leu Val Leu Leu Asp Thr Glu Gly Leu Gly Asp Val Glu
                  95                 100                 105

 Lys Ala Asp Asn Lys Asn Asp Ile Gln Ile Phe Ala Leu Ala Leu
                 110                 115                 120

 Leu Leu Ser Ser Thr Phe Val Tyr Asn Thr Val Asn Lys Ile Asp
                 125                 130                 135

 Gln Gly Ala Ile Asp Leu Leu His Asn Val Thr Glu Leu Thr Asp
                 140                 145                 150

 Leu Leu Lys Ala Arg Asn Ser Pro Asp Leu Asp Arg Val Glu Asp
                 155                 160                 165

 Pro Ala Asp Ser Ala Ser Phe Phe Pro Asp Leu Val Trp Thr Leu
                 170                 175                 180

 Arg Asp Phe Cys Leu Gly Leu Glu Ile Asp Gly Gln Leu Val Thr
                 185                 190                 195

 Pro Asp Glu Tyr Leu Glu Asn Ser Leu Arg Pro Lys Gln Gly Ser
                 200                 205                 210

 Asp Gln Arg Val Gln Asn Phe Asn Leu Pro Arg Leu Cys Ile Gln
                 215                 220                 225

 Lys Phe Phe Pro Lys Lys Lys Cys Phe Ile Phe Asp Leu Pro Ala
                 230                 235                 240

 His Gln Lys Lys Leu Ala Gln Leu Glu Thr Leu Pro Asp Asp Glu
                 245                 250                 255

 Leu Glu Pro Glu Phe Val Gln Gln Val Thr Glu Phe Cys Ser Tyr
                 260                 265                 270

 Ile Phe Ser His Ser Met Thr Lys Thr Leu Pro Gly Gly Ile Met
                 275                 280                 285

 Val Asn Gly Ser Arg Leu Lys Asn Leu Val Leu Thr Tyr Val Asn
                 290                 295                 300

 Ala Ile Ser Ser Gly Asp Leu Pro Cys Ile Glu Asn Ala Val Leu
                 305                 310                 315

 Ala Leu Ala Gln Arg Glu Asn Ser Ala Ala Val Gln Lys Ala Ile
                 320                 325                 330

 Ala His Tyr Asp Gln Gln Met Gly Gln Lys Val Gln Leu Pro Met
                 335                 340                 345

 Glu Thr Leu Gln Glu Leu Leu Asp Leu His Arg Thr Ser Glu Arg
                 350                 355                 360

 Glu Ala Ile Glu Val Phe Met Lys Asn Ser Phe Lys Asp Val Asp
                 365                 370                 375

 Gln Ser Phe Gln Lys Glu Leu Glu Thr Leu Leu Asp Ala Lys Gln
                 380                 385                 390

 Asn Asp Ile Cys Lys Arg Asn Leu Glu Ala Ser Ser Asp Tyr Cys
                 395                 400                 405

 Ser Ala Leu Leu Lys Asp Ile Phe Gly Pro Leu Glu Glu Ala Val
                 410                 415                 420

 Lys Gln Gly Ile Tyr Ser Lys Pro Gly Gly His Asn Leu Phe Ile
                 425                 430                 435

 Gln Lys Thr Glu Glu Leu Lys Ala Lys Tyr Tyr Arg Glu Pro Arg
                 440                 445                 450

 Lys Gly Ile Gln Ala Glu Glu Val Leu Gln Lys Tyr Leu Lys Ser
                 455                 460                 465

 Lys Glu Ser Val Ser His Ala Ile Leu Gln Thr Asp Gln Ala Leu
                 470                 475                 480

 Thr Glu Thr Glu Lys Lys Lys Lys Glu Ala Gln Val Lys Ala Glu
                 485                 490                 495

 Ala Glu Lys Ala Glu Ala Gln Arg Leu Ala Ala Ile Gln Arg Gln
                 500                 505                 510

 Asn Glu Gln Met Met Gln Glu Arg Glu Arg Leu His Gln Glu Gln
                 515                 520                 525

 Val Arg Gln Met Glu Ile Ala Lys Gln Asn Trp Leu Ala Glu Gln
                 530                 535                 540

 Gln Lys Met Gln Glu Gln Gln Met Gln Glu Gln Ala Ala Gln Leu
                 545                 550                 555

 Ser Thr Thr Phe Gln Ala Gln Asn Arg Ser Leu Leu Ser Glu Leu
                 560                 565                 570

 Gln His Ala Gln Arg Thr Val Asn Asn Asp Asp Pro Cys Val Leu
                 575                 580                 585

 Leu


<210> 5208
<211> 1726
<212> DNA
<213> Homo sapien

<400> 5208
 gtcaggttca tggttacgaa gctgctgacc ccaggatccc agcccgtggg 50

 agagaagggg gtctctgaca gcccccaccc ctccccactg ccagatcctt 100

 attgggtctg agtttcaggg gtggggcccc agctggaggt tataaaacag 150

 ctcaatcggg gagtacaacc ttcggtttct cttcggggaa agctgctttc 200

 agcgcacacg ggaagatatc agaaacatcc taggatcagg acaccccaga 250

 tcttctcaac tggaaccacg aaggctgttt cttccacaca gcactttgat 300

 ctccatttaa gcaggcacct ctgtcctgcg ttccggagct gcgttcccga 350

 tggtcctcct ttggctcacg ctgctcctga tcgccctgcc ctgtctcctg 400

 caaacgaagg aagatccaaa cccaccaatc acgaacctaa ggatgaaagc 450

 aaaggctcag cagttgacct gggaccttaa cagaaatgtg accgatatcg 500

 agtgtgttaa agacgccgac tattctatgc cggcagtgaa caatagctat 550

 tgccagtttg gagcaatttc cttatgtgaa gtgaccaact acaccgtccg 600

 agtggccaac ccaccattct ccacgtggat cctcttccct gagaacagtg 650

 ggaagccttg ggcaggtgcg gagaatctga cctgctggat tcatgacgtg 700

 gatttcttga gctgcagctg ggcggtaggc ccgggggccc ccgcggacgt 750

 ccagtacgac ctgtacttga acgttgccaa caggcgtcaa cagtacgagt 800

 gtcttcacta caaaacggat gctcagggaa cacgtatcgg gtgtcgtttc 850

 gatgacatct ctcgactctc cagcggttct caaagttccc acatcctggt 900

 gcggggcagg agcgcagcct tcggtatccc ctgcacagat aagtttgtcg 950

 tcttttcaca gattgagata ttaactccac ccaacatgac tgcaaagtgt 1000

 aataagacac attcctttat gcactggaaa atgagaagtc atttcaatcg 1050

 caaatttcgc tatgagcttc agatacaaaa gagaatgcag cctgtaatca 1100

 cagaacaggt cagagacaga acctccttcc agctactcaa tcctggaacg 1150

 tacacagtac aaataagagc ccgggaaaga gtgtatgaat tcttgagcgc 1200

 ctggagcacc ccccagcgct tcgagtgcga ccaggaggag ggcgcaaaca 1250

 cacgtgcctg gcggacgtcg ctgctgatcg cgctggggac gctgctggcc 1300

 ctggtctgtg tcttcgtgat ctgcagaagg tatctggtga tgcagagact 1350

 ctttccccgc atccctcaca tgaaagaccc catcggtgac agcttccaaa 1400

 acgacaagct ggtggtctgg gaggcgggca aagccggcct ggaggagtgt 1450

 ctggtgactg aagtacaggt cgtgcagaaa acttgagact ggggttcagg 1500

 gcttgtgggg gtctgcctca atctccctgg ccgggccagg cgcctgcaca 1550

 gactggctgc tggacctgcg cacgcagccc aggaatggac attcctaacg 1600

 ggtggtgggc atgggagatg cctgtgtaat ttcgtccgaa gctgccagga 1650

 agaagaacag aactttgtgt gtttatttca tgataaagtg attttttttt 1700

 ttttaaccca aaaaaaaaaa aaaaaa 1726

<210> 5209
<211> 378
<212> PRT
<213> Homo sapien

<400> 5209
 Met Val Leu Leu Trp Leu Thr Leu Leu Leu Ile Ala Leu Pro Cys
   1               5                  10                  15

 Leu Leu Gln Thr Lys Glu Asp Pro Asn Pro Pro Ile Thr Asn Leu
                  20                  25                  30

 Arg Met Lys Ala Lys Ala Gln Gln Leu Thr Trp Asp Leu Asn Arg
                  35                  40                  45

 Asn Val Thr Asp Ile Glu Cys Val Lys Asp Ala Asp Tyr Ser Met
                  50                  55                  60

 Pro Ala Val Asn Asn Ser Tyr Cys Gln Phe Gly Ala Ile Ser Leu
                  65                  70                  75

 Cys Glu Val Thr Asn Tyr Thr Val Arg Val Ala Asn Pro Pro Phe
                  80                  85                  90

 Ser Thr Trp Ile Leu Phe Pro Glu Asn Ser Gly Lys Pro Trp Ala
                  95                 100                 105

 Gly Ala Glu Asn Leu Thr Cys Trp Ile His Asp Val Asp Phe Leu
                 110                 115                 120

 Ser Cys Ser Trp Ala Val Gly Pro Gly Ala Pro Ala Asp Val Gln
                 125                 130                 135

 Tyr Asp Leu Tyr Leu Asn Val Ala Asn Arg Arg Gln Gln Tyr Glu
                 140                 145                 150

 Cys Leu His Tyr Lys Thr Asp Ala Gln Gly Thr Arg Ile Gly Cys
                 155                 160                 165

 Arg Phe Asp Asp Ile Ser Arg Leu Ser Ser Gly Ser Gln Ser Ser
                 170                 175                 180

 His Ile Leu Val Arg Gly Arg Ser Ala Ala Phe Gly Ile Pro Cys
                 185                 190                 195

 Thr Asp Lys Phe Val Val Phe Ser Gln Ile Glu Ile Leu Thr Pro
                 200                 205                 210

 Pro Asn Met Thr Ala Lys Cys Asn Lys Thr His Ser Phe Met His
                 215                 220                 225

 Trp Lys Met Arg Ser His Phe Asn Arg Lys Phe Arg Tyr Glu Leu
                 230                 235                 240

 Gln Ile Gln Lys Arg Met Gln Pro Val Ile Thr Glu Gln Val Arg
                 245                 250                 255

 Asp Arg Thr Ser Phe Gln Leu Leu Asn Pro Gly Thr Tyr Thr Val
                 260                 265                 270

 Gln Ile Arg Ala Arg Glu Arg Val Tyr Glu Phe Leu Ser Ala Trp
                 275                 280                 285

 Ser Thr Pro Gln Arg Phe Glu Cys Asp Gln Glu Glu Gly Ala Asn
                 290                 295                 300

 Thr Arg Ala Trp Arg Thr Ser Leu Leu Ile Ala Leu Gly Thr Leu
                 305                 310                 315

 Leu Ala Leu Val Cys Val Phe Val Ile Cys Arg Arg Tyr Leu Val
                 320                 325                 330

 Met Gln Arg Leu Phe Pro Arg Ile Pro His Met Lys Asp Pro Ile
                 335                 340                 345

 Gly Asp Ser Phe Gln Asn Asp Lys Leu Val Val Trp Glu Ala Gly
                 350                 355                 360

 Lys Ala Gly Leu Glu Glu Cys Leu Val Thr Glu Val Gln Val Val
                 365                 370                 375

 Gln Lys Thr


<210> 5210
<211> 2166
<212> DNA
<213> Homo sapien

<400> 5210
 tgcgggtgag gctggcgccc gtaccatgag cgaggcggac gggctgcgac 50

 agcgccggcc cctgcggccg caggtcgtca cagacgatga tggccaggcc 100

 ccggaggcta aggacggcag ctcctttagc ggcagagttt tccgagtgac 150

 cttcttgatg ctggctgttt ctctcaccgt tcccctgctt ggagccatga 200

 tgctgctgga atctcctata gatccacagc ctctcagctt caaagaaccc 250

 ccgctcttgc ttggtgttct gcatccaaat acgaagctgc gacaggcaga 300

 aaggctgttt gaaaatcaac ttgttggacc ggagtccata gcacatattg 350

 gggatgtgat gtttactggg acagcagatg gccgggtcgt aaaacttgaa 400

 aatggtgaaa tagagaccat tgcccggttt ggttcgggcc cttgcaaaac 450

 ccgagatgat gagcctgtgt gtgggagacc cctgggtatc cgtgcagggc 500

 ccaatgggac tctctttgtg gccgatgcat acaagggact atttgaagta 550

 aatccctgga aacgtgaagt gaaactgctg ctgtcctccg agacacccat 600

 tgaggggaag aacatgtcct ttgtgaatga tcttacagtc actcaggatg 650

 ggaggaagat ttatttcacc gattctagca gcaaatggca aagacgagac 700

 tacctgcttc tggtgatgga gggcacagat gacgggcgcc tgctggagta 750

 tgatactgtg accagggaag taaaagtttt attggaccag ctgcggttcc 800

 cgaatggagt ccagctgtct cctgcagaag actttgtcct ggtggcagaa 850

 acaaccatgg ccaggatacg aagagtctac gtttctggcc tgatgaaggg 900

 cggggctgat ctgtttgtgg agaacatgcc tggatttcca gacaacatcc 950

 ggcccagcag ctctgggggg tactgggtgg gcatgtcgac catccgccct 1000

 aaccctgggt tttccatgct ggatttctta tctgagagac cctggattaa 1050

 aaggatgatt tttaagctct ttagtcaaga gacggtgatg aagtttgtgc 1100

 cgcggtacag cctcgtccta gaactcagcg acagcggtgc cttccggaga 1150

 agcctgcatg atcccgatgg gctggtggcc acctacatca gcgaggtgca 1200

 cgaacacgat gggcacctgt acctgggctc tttcaggtcc cccttcctct 1250

 gcagactcag cctccaggct gtttagccct cccagatagc tgcccctgcc 1300

 acgcaggcca ggagtcttca cactcaggca ccaggcctgg tccaggagga 1350

 gctgtggaca cagtcgtggt tcaagtgtcc acatgcacct attagtccct 1400

 gagaggtggt gggaatggct gcttcattcc tcgaggatgc ccgggcccca 1450

 cctgggcttg tctttctgtt tagagggaag tgtaacatat ctgccatgag 1500

 gaacataaat tcatgtaaag ccattttctc ttaaacaaaa caaaactttc 1550

 taagtacagt cattctctag gatttgggaa gctccttgca cttggaacag 1600

 ggctcaggtg ggtggagcag taaggcacta cccagagagc ttgctgctgc 1650

 ggccctgtcc tgcggcctca aagttcttct ttactatata taacgtgcgg 1700

 tcataccttt cttcgttgtg gtggggatgg aagagcagag ggagcatggc 1750

 ccaggggtgt tgaggccagc ggtgagagcc gtgttagcca agacatggaa 1800

 ctgtgttctc aagggttatg tggggcgtgg gctctccata gtgtgtatga 1850

 aaagcttgtt gactctagcg gctcagagag gactttgctg ggtttctttc 1900

 tgtgaatatc tccgtgctga ccatgctgga attggatgat tctgcaattc 1950

 gggacctact gcaggggtcc gtttagtaac gtcttgtctg tgatctttgt 2000

 tcttgacctc tagaccccaa gatgtgaaca gtgcacgtgt taatgtcatc 2050

 tttgctcatg tgttataagc cccaagttgc tgtatatttt cacaagtatg 2100

 tctacacact ggtcatgatt ttgataataa ataacgataa atcgaaaaaa 2150

 aaaaaaaaaa aaaaaa 2166

<210> 5211
<211> 416
<212> PRT
<213> Homo sapien

<400> 5211
 Met Ser Glu Ala Asp Gly Leu Arg Gln Arg Arg Pro Leu Arg Pro
   1               5                  10                  15

 Gln Val Val Thr Asp Asp Asp Gly Gln Ala Pro Glu Ala Lys Asp
                  20                  25                  30

 Gly Ser Ser Phe Ser Gly Arg Val Phe Arg Val Thr Phe Leu Met
                  35                  40                  45

 Leu Ala Val Ser Leu Thr Val Pro Leu Leu Gly Ala Met Met Leu
                  50                  55                  60

 Leu Glu Ser Pro Ile Asp Pro Gln Pro Leu Ser Phe Lys Glu Pro
                  65                  70                  75

 Pro Leu Leu Leu Gly Val Leu His Pro Asn Thr Lys Leu Arg Gln
                  80                  85                  90

 Ala Glu Arg Leu Phe Glu Asn Gln Leu Val Gly Pro Glu Ser Ile
                  95                 100                 105

 Ala His Ile Gly Asp Val Met Phe Thr Gly Thr Ala Asp Gly Arg
                 110                 115                 120

 Val Val Lys Leu Glu Asn Gly Glu Ile Glu Thr Ile Ala Arg Phe
                 125                 130                 135

 Gly Ser Gly Pro Cys Lys Thr Arg Asp Asp Glu Pro Val Cys Gly
                 140                 145                 150

 Arg Pro Leu Gly Ile Arg Ala Gly Pro Asn Gly Thr Leu Phe Val
                 155                 160                 165

 Ala Asp Ala Tyr Lys Gly Leu Phe Glu Val Asn Pro Trp Lys Arg
                 170                 175                 180

 Glu Val Lys Leu Leu Leu Ser Ser Glu Thr Pro Ile Glu Gly Lys
                 185                 190                 195

 Asn Met Ser Phe Val Asn Asp Leu Thr Val Thr Gln Asp Gly Arg
                 200                 205                 210

 Lys Ile Tyr Phe Thr Asp Ser Ser Ser Lys Trp Gln Arg Arg Asp
                 215                 220                 225

 Tyr Leu Leu Leu Val Met Glu Gly Thr Asp Asp Gly Arg Leu Leu
                 230                 235                 240

 Glu Tyr Asp Thr Val Thr Arg Glu Val Lys Val Leu Leu Asp Gln
                 245                 250                 255

 Leu Arg Phe Pro Asn Gly Val Gln Leu Ser Pro Ala Glu Asp Phe
                 260                 265                 270

 Val Leu Val Ala Glu Thr Thr Met Ala Arg Ile Arg Arg Val Tyr
                 275                 280                 285

 Val Ser Gly Leu Met Lys Gly Gly Ala Asp Leu Phe Val Glu Asn
                 290                 295                 300

 Met Pro Gly Phe Pro Asp Asn Ile Arg Pro Ser Ser Ser Gly Gly
                 305                 310                 315

 Tyr Trp Val Gly Met Ser Thr Ile Arg Pro Asn Pro Gly Phe Ser
                 320                 325                 330

 Met Leu Asp Phe Leu Ser Glu Arg Pro Trp Ile Lys Arg Met Ile
                 335                 340                 345

 Phe Lys Leu Phe Ser Gln Glu Thr Val Met Lys Phe Val Pro Arg
                 350                 355                 360

 Tyr Ser Leu Val Leu Glu Leu Ser Asp Ser Gly Ala Phe Arg Arg
                 365                 370                 375

 Ser Leu His Asp Pro Asp Gly Leu Val Ala Thr Tyr Ile Ser Glu
                 380                 385                 390

 Val His Glu His Asp Gly His Leu Tyr Leu Gly Ser Phe Arg Ser
                 395                 400                 405

 Pro Phe Leu Cys Arg Leu Ser Leu Gln Ala Val
                 410                 415

<210> 5212
<211> 2082
<212> DNA
<213> Homo sapien

<400> 5212
 cttggctgga acctgagacg gattcgctcc caaatgatgc tccagtggct 50

 ggagcaactc aagttcatca ttgtcctgag agagaggagc agcgcggttc 100

 tcggccggga cagcagaacg ccaggggacc ctcacctggg cgcgccgggg 150

 cacgggcttt gattgtcctg gggtcgcgga gacccgcgcg cctgccctgc 200

 acgccgggcg gcaacctttg cagtcgcgtt ggctgctgcg atcggccggc 250

 gggtccctgc cgaaggctcg gctgcttctg tccacctctt acacttcttc 300

 atttatcggt ggatcatttc gagagtccgt cttgtaaatg tttggcactt 350

 tgctacttta ttgcttcttt ctggcgacag ttccagcact cgccgagacc 400

 ggcggagaaa ggcagctgag cccggagaag agcgaaatat ggggacccgg 450

 gctaaaagca gacgtcgtcc ttcccgcccg ctatttctat attcaggcag 500

 tggatacatc agggaataaa ttcacatctt ctccaggcga aaaggtcttc 550

 caggtgaaag tctcagcacc agaggagcaa ttcactagag ttggagtcca 600

 ggttttagac cgaaaagatg ggtccttcat agtaagatac agaatgtatg 650

 caagctacaa aaatctgaag gtggaagtta aattccaagg gcaacatgtg 700

 gccaaatccc catatatttt aaaagggccg gtttaccatg agaactgtga 750

 ctgtcctctg caagatagtg cagcctggct acgggagatg aactgccctg 800

 aaaccattgc tcagattcag agagatctgg cacatttccc tgctgtggat 850

 ccagaaaaga ttgcagtaga aatcccaaaa agatttggac agaggcagag 900

 cctatgtcac tacaccttaa aggataacaa ggtttatatc aagactcatg 950

 gtgaacatgt aggttttaga attttcatgg atgccatact actttctttg 1000

 actagaaagg tgaagatgcc agatgtggag ctctttgtta atttgggaga 1050

 ctggcctttg gaaaaaaaga aatccaattc aaacatccat ccgatctttt 1100

 cctggtgtgg ctccacagat tccaaggata tcgtgatgcc tacgtacgat 1150

 ttgactgatt ctgttctgga aaccatgggc cgggtaagtc tggatatgat 1200

 gtccgtgcaa gctaacacgg gtcctccctg ggaaagcaaa aattccactg 1250

 ccgtctggag agggcgagac agccgcaaag agagactcga gctggttaaa 1300

 ctcagtagaa aacacccaga actcatagac gctgctttca ccaacttttt 1350

 cttctttaaa cacgatgaaa acctgtatgg tcccattgtg aaacatattt 1400

 cattttttga tttcttcaag cataagtatc aaataaatat cgatggcact 1450

 gtagcagctt atcgcctgcc atatttgcta gttggtgaca gtgttgtgct 1500

 gaagcaggat tccatctact atgaacattt ttacaatgag ctgcagccct 1550

 ggaaacacta cattccagtt aagagcaacc tgagcgatct gctagaaaaa 1600

 cttaaatggg cgaaagatca cgatgaagag gccaaaaaga tagcaaaagc 1650

 aggacaagaa tttgcaagaa ataatctcat gggcgatgac atattctgtt 1700

 attatttcaa acttttccag gaatatgcca atttacaagt gagtgagccc 1750

 caaatccgag agggcatgaa aagggtagaa ccacagactg aggacgacct 1800

 cttcccttgt acttgccata ggaaaaagac caaagatgaa ctctgatatg 1850

 caaaataact tctattagaa taatggtgct ctgaagactc ttcttaacta 1900

 aaaagaagaa tttttttaag tattaattcc atggacaata taaaatctgt 1950

 gtgattgttt gcagtatgaa gacacatttc tacttatgca gtattctcat 2000

 gactgtactt taaagtacat ttttagaatt ttataataaa accaccttta 2050

 ttttaaagga aaaaaaaaaa aaaaaaaaaa aa 2082

<210> 5213
<211> 502
<212> PRT
<213> Homo sapien

<400> 5213
 Met Phe Gly Thr Leu Leu Leu Tyr Cys Phe Phe Leu Ala Thr Val
   1               5                  10                  15

 Pro Ala Leu Ala Glu Thr Gly Gly Glu Arg Gln Leu Ser Pro Glu
                  20                  25                  30

 Lys Ser Glu Ile Trp Gly Pro Gly Leu Lys Ala Asp Val Val Leu
                  35                  40                  45

 Pro Ala Arg Tyr Phe Tyr Ile Gln Ala Val Asp Thr Ser Gly Asn
                  50                  55                  60

 Lys Phe Thr Ser Ser Pro Gly Glu Lys Val Phe Gln Val Lys Val
                  65                  70                  75

 Ser Ala Pro Glu Glu Gln Phe Thr Arg Val Gly Val Gln Val Leu
                  80                  85                  90

 Asp Arg Lys Asp Gly Ser Phe Ile Val Arg Tyr Arg Met Tyr Ala
                  95                 100                 105

 Ser Tyr Lys Asn Leu Lys Val Glu Val Lys Phe Gln Gly Gln His
                 110                 115                 120

 Val Ala Lys Ser Pro Tyr Ile Leu Lys Gly Pro Val Tyr His Glu
                 125                 130                 135

 Asn Cys Asp Cys Pro Leu Gln Asp Ser Ala Ala Trp Leu Arg Glu
                 140                 145                 150

 Met Asn Cys Pro Glu Thr Ile Ala Gln Ile Gln Arg Asp Leu Ala
                 155                 160                 165

 His Phe Pro Ala Val Asp Pro Glu Lys Ile Ala Val Glu Ile Pro
                 170                 175                 180

 Lys Arg Phe Gly Gln Arg Gln Ser Leu Cys His Tyr Thr Leu Lys
                 185                 190                 195

 Asp Asn Lys Val Tyr Ile Lys Thr His Gly Glu His Val Gly Phe
                 200                 205                 210

 Arg Ile Phe Met Asp Ala Ile Leu Leu Ser Leu Thr Arg Lys Val
                 215                 220                 225

 Lys Met Pro Asp Val Glu Leu Phe Val Asn Leu Gly Asp Trp Pro
                 230                 235                 240

 Leu Glu Lys Lys Lys Ser Asn Ser Asn Ile His Pro Ile Phe Ser
                 245                 250                 255

 Trp Cys Gly Ser Thr Asp Ser Lys Asp Ile Val Met Pro Thr Tyr
                 260                 265                 270

 Asp Leu Thr Asp Ser Val Leu Glu Thr Met Gly Arg Val Ser Leu
                 275                 280                 285

 Asp Met Met Ser Val Gln Ala Asn Thr Gly Pro Pro Trp Glu Ser
                 290                 295                 300

 Lys Asn Ser Thr Ala Val Trp Arg Gly Arg Asp Ser Arg Lys Glu
                 305                 310                 315

 Arg Leu Glu Leu Val Lys Leu Ser Arg Lys His Pro Glu Leu Ile
                 320                 325                 330

 Asp Ala Ala Phe Thr Asn Phe Phe Phe Phe Lys His Asp Glu Asn
                 335                 340                 345

 Leu Tyr Gly Pro Ile Val Lys His Ile Ser Phe Phe Asp Phe Phe
                 350                 355                 360

 Lys His Lys Tyr Gln Ile Asn Ile Asp Gly Thr Val Ala Ala Tyr
                 365                 370                 375

 Arg Leu Pro Tyr Leu Leu Val Gly Asp Ser Val Val Leu Lys Gln
                 380                 385                 390

 Asp Ser Ile Tyr Tyr Glu His Phe Tyr Asn Glu Leu Gln Pro Trp
                 395                 400                 405

 Lys His Tyr Ile Pro Val Lys Ser Asn Leu Ser Asp Leu Leu Glu
                 410                 415                 420

 Lys Leu Lys Trp Ala Lys Asp His Asp Glu Glu Ala Lys Lys Ile
                 425                 430                 435

 Ala Lys Ala Gly Gln Glu Phe Ala Arg Asn Asn Leu Met Gly Asp
                 440                 445                 450

 Asp Ile Phe Cys Tyr Tyr Phe Lys Leu Phe Gln Glu Tyr Ala Asn
                 455                 460                 465

 Leu Gln Val Ser Glu Pro Gln Ile Arg Glu Gly Met Lys Arg Val
                 470                 475                 480

 Glu Pro Gln Thr Glu Asp Asp Leu Phe Pro Cys Thr Cys His Arg
                 485                 490                 495

 Lys Lys Thr Lys Asp Glu Leu
                 500

<210> 5214
<211> 1705
<212> DNA
<213> Homo sapien

<400> 5214
 gtttttttcc cttctgagca atggagctta ccatctttat cctgagactg 50

 gccatttaca tcctgacatt tcccttgtac ctgctgaact ttctgggctt 100

 gtggagctgg atatgcaaaa aatggttccc ctacttcttg gtgaggttca 150

 ctgtgatata caacgaacag atggcaagca agaagcggga gctcttcagt 200

 aacctgcagg agtttgcggg cccctccggg aaactctccc tgctggaagt 250

 gggctgtggc acgggggcca acttcaagtt ctacccacct gggtgcaggg 300

 tgacctgtat tgaccccaac cccaactttg agaagttttt gatcaagagc 350

 attgcagaga accgacacct gcagtttgag cgctttgtgg tagctgccgg 400

 ggagaacatg caccaggtgg ctgatggctc tgtggatgtg gtggtctgca 450

 ccctggtgct gtgctctgtg aagaaccagg agcggattct ccgcgaggtg 500

 tgcagagtgc tgagaccggg aggggctttc tatttcatgg agcatgtggc 550

 agctgagtgt tcgacttgga attacttctg gcaacaagtc ctggatcctg 600

 cctggcacct tctgtttgat gggtgcaacc tgaccagaga gagctggaag 650

 gccctggagc gggccagctt ctctaagctg aagctgcagc acatccaggc 700

 cccactgtcc tgggagttgg tgcgccctca tatctatgga tatgctgtga 750

 aatagtgtga gctggcagtt aagagctgaa tggctcaaag aatttaaagc 800

 ttcagtttta catttaaaat gctaagtggg agaagagaaa cctttttttt 850

 ggggggcggt ttttttggtt tgttgttggt tttttttttt tttttggcaa 900

 gactccgtct caaaaaaaaa aaaaaaaaaa aaaagaagta gagacaggga 950

 gacagggtct cactgtgttg cctaggccgg tcttgaactc ctgggctcaa 1000

 gtgattctcc caccttgacc tcctaaattg ttgggattac aggtgtgaga 1050

 cagtgcacct ggccgaaata gctcaagttt ctgaaaaaca aatctgaatc 1100

 tatttgttat tcttagcgtc actggtctgg ctttcagaat taacatacaa 1150

 ggttgccaca cctagttctg cccagcttta tgtcttttat tccagtattc 1200

 caccaaagtt tgttttcctg cattccagtt ctcaagtctt aagataaaga 1250

 ttgtacttga cagtttagta tatccataaa actatttgag gtggttaagg 1300

 ttcttgggtt cattttcctt aatactttgc tgaatattgt agattgtagg 1350

 caatgaaaaa gtctactaaa ttaggaaaac cttgaataat taggtatcct 1400

 aggtaagagc ccctaaacat caagcaatct gtgagtctgt aaagaaataa 1450

 atattttttg gattattctt atctaattcc acccctgttg gaagatgatt 1500

 tctttgttct ttgcaactat ggaagctgtg aaaatcatca caagtgcctc 1550

 tgaaagcgag tgttaggttg gttagagggt ttaatatttt ctgcaatggt 1600

 ttgtaggaat tttaataaat gtagtatatt ttctgagatg attttgtaaa 1650

 agtactattt taaatatcaa atcaaccaat aaattcacat ttgtgttagg 1700

 aacag 1705

<210> 5215
<211> 244
<212> PRT
<213> Homo sapien

<400> 5215
 Met Glu Leu Thr Ile Phe Ile Leu Arg Leu Ala Ile Tyr Ile Leu
   1               5                  10                  15

 Thr Phe Pro Leu Tyr Leu Leu Asn Phe Leu Gly Leu Trp Ser Trp
                  20                  25                  30

 Ile Cys Lys Lys Trp Phe Pro Tyr Phe Leu Val Arg Phe Thr Val
                  35                  40                  45

 Ile Tyr Asn Glu Gln Met Ala Ser Lys Lys Arg Glu Leu Phe Ser
                  50                  55                  60

 Asn Leu Gln Glu Phe Ala Gly Pro Ser Gly Lys Leu Ser Leu Leu
                  65                  70                  75

 Glu Val Gly Cys Gly Thr Gly Ala Asn Phe Lys Phe Tyr Pro Pro
                  80                  85                  90

 Gly Cys Arg Val Thr Cys Ile Asp Pro Asn Pro Asn Phe Glu Lys
                  95                 100                 105

 Phe Leu Ile Lys Ser Ile Ala Glu Asn Arg His Leu Gln Phe Glu
                 110                 115                 120

 Arg Phe Val Val Ala Ala Gly Glu Asn Met His Gln Val Ala Asp
                 125                 130                 135

 Gly Ser Val Asp Val Val Val Cys Thr Leu Val Leu Cys Ser Val
                 140                 145                 150

 Lys Asn Gln Glu Arg Ile Leu Arg Glu Val Cys Arg Val Leu Arg
                 155                 160                 165

 Pro Gly Gly Ala Phe Tyr Phe Met Glu His Val Ala Ala Glu Cys
                 170                 175                 180

 Ser Thr Trp Asn Tyr Phe Trp Gln Gln Val Leu Asp Pro Ala Trp
                 185                 190                 195

 His Leu Leu Phe Asp Gly Cys Asn Leu Thr Arg Glu Ser Trp Lys
                 200                 205                 210

 Ala Leu Glu Arg Ala Ser Phe Ser Lys Leu Lys Leu Gln His Ile
                 215                 220                 225

 Gln Ala Pro Leu Ser Trp Glu Leu Val Arg Pro His Ile Tyr Gly
                 230                 235                 240

 Tyr Ala Val Lys


<210> 5216
<211> 3848
<212> DNA
<213> Homo sapien

<400> 5216
 ggcagcttct caggtcagcc tcctccgggc ctctccccac tctcctctgc 50

 ccagttctct gtccttatcc acaggcccct cagtgggcac tggccatacc 100

 catgtccagg tgggcacagg cctggtgata tcctggtgag caagctgggg 150

 acccaccctc cttccctttc tggttggcag ctccacatct ggggcaatgt 200

 agagatctgt gcttttggaa ggaggggcaa tttaaattaa gaagtggtta 250

 ggcatgggtc tcgaatctta gcttccccgc gaggtctggg acaagtgaag 300

 agaggtttct tttctggacc tcagtttctc atctgtaaaa tggggtgagt 350

 ctgggaacct gcaccttgga tggctgtcag gggctcagta gaggacctgg 400

 cacacagttt gtgcttggca atctggagca ggtgcagctc ctttcagagt 450

 gacctggatt ggatcctggg gacagcatgt ctcagggccg gagccagttc 500

 ttggaggaga ctctgcgcag ggcatggatc actgtggtgc ccttttcctg 550

 tgcctgtgcc ttctgacttt gcagaatgca acaacagaga catgggaaga 600

 actcctgagc tacatggaga atatgcaggt gtccaggggc cggagctcag 650

 ttttttcctc tcgtcaactc caccagctgg agcagatgct actgaacacc 700

 agcttcccag gctacaacct gaccttgcag acacccacca tccagtctct 750

 ggccttcaag ctgagctgtg acttctctgg cctctcgctg accagtgcca 800

 ctctgaagcg ggtgccccag gcaggaggtc agcatgcccg gggtcagcac 850

 gccatgcagt tccccgccga gctgacccgg gacgcctgca agacccgccc 900

 cagggagctg cggctcatct gtatctactt ctccaacacc cactttttca 950

 aggatgaaaa caactcatct ctgctgaata actacgtcct gggggcccag 1000

 ctgagtcatg ggcacgtgaa caacctcagg gatcctgtga acatcagctt 1050

 ctggcacaac caaagcctgg aaggctacac cctgacctgt gtcttctgga 1100

 aggagggagc caggaaacag ccctgggggg gctggagccc tgagggctgt 1150

 cgtacagagc agccctccca ctctcaggtg ctctgccgct gcaaccacct 1200

 cacctacttt gctgttctca tgcaactctc cccagccctg gtccctgcag 1250

 agttgctggc acctcttacg tacatctccc tcgtgggctg cagcatctcc 1300

 atcgtggcct cgctgatcac agtcctgctg cacttccatt tcaggaagca 1350

 gagtgactcc ttaacacgca tccacatgaa cctgcatgcc tccgtgctgc 1400

 tcctgaacat cgccttcctg ctgagccccg cattcgcaat gtctcctgtg 1450

 cccgggtcag catgcacggc tctggccgct gccctgcact acgcgctgct 1500

 cagctgcctc acctggatgg ccatcgaggg cttcaacctc tacctcctcc 1550

 tcgggcgtgt ctacaacatc tacatccgca gatatgtgtt caagcttggt 1600

 gtgctaggct ggggggcccc agccctcctg gtgctgcttt ccctctctgt 1650

 caagagctcg gtatacggac cctgcacaat ccccgtcttc gacagctggg 1700

 agaatggcac aggcttccag aacatgtcca tatgctgggt gcggagcccc 1750

 gtggtgcaca gtgtcctggt catgggctac ggcggcctca cgtccctctt 1800

 caacctggtg gtgctggcct gggcgctgtg gaccctgcgc aggctgcggg 1850

 agcgggcgga tgcaccaagt gtcagggcct gccatgacac tgtcactgtg 1900

 ctgggcctca ccgtgctgct gggaaccacc tgggccttgg ccttcttttc 1950

 ttttggcgtc ttcctgctgc cccagctgtt cctcttcacc atcttaaact 2000

 cgctctacgg tttcttcctt ttcctgtggt tctgctccca gcggtgccgc 2050

 tcagaagcag aggccaaggc acagatagag gccttcagct cctcccaaac 2100

 aacacagtag tccgggcctc ctggcctgga atcctcagcc tctctggccg 2150

 ccagtagcct gaggctacgg ctcctgctag agagggtggc aggcctgctg 2200

 ctggacccca gaggccactg tgaccgccaa ggggcctttt ccacttccac 2250

 ggcctctcca ggcactgagg ggaaggcatt gctctacctc tccctgacat 2300

 tttgctccgg ggcagatcca accttacctg gggcagcaaa ctttgtcctg 2350

 gtacctgggc ccagctcgcc agggatgtgg gcagagcacc agcctgggca 2400

 tcaggaagcc aagtttcaag gactgtcttt gagtctgtct gtatgacctt 2450

 gggcctgcca cttctcacag accctaggta tccacagctg tgacatgggg 2500

 gcaagcggct ttgtttcagc ctaacccagg agcttagtaa aaattgcata 2550

 agaccagggg gaagagtgtc agcgtggggt gggaattccc gcggcctcca 2600

 cctgcttgct aggggcagga tctcattcag gctgccctgg aagcacctgc 2650

 ttggccctgc caccttcctc caggggaggg ccagatggca tcctggcttg 2700

 gggcgggtgg gacctaccca ggctctgaga ctttactggc ctatgcctga 2750

 ggcctctttt cctttaactc cctaaattat gatgactcca agtccaagcc 2800

 cacccttccc aaagattggg aggttccgcc gttcccagag gctcctcctg 2850

 cggtgctccc aagacttcca tagaccatct ggaccagtag cccatcccgc 2900

 agttttcttg ggggcagagg aaaacgcttc tttctcctcc agctgaatca 2950

 gctggatccc agtgtcctgg ctgtttggtg attgggcaag attgaatttg 3000

 cccaggtagg cgtgagagtg tgggttttaa attcgaagct caggccatag 3050

 tttcagagaa tcacccttac cccagacctt catgagacag tgctcatgaa 3100

 gccagtgcgt ttcccagaac gaacactagg cggcaccgtt ggtccacact 3150

 cagaggccct tggcgccaag actgcatcta gaatcgctca aacacctgtt 3200

 tgcagacccc atgcaccagc tggaggggcc gtaactgcag gactgcgcct 3250

 actgagtgac ccatttcctc caggaggaaa ggcaagacac gcttacacgg 3300

 ccatttgtct cttttcccaa tgcggcggtg cactttcgct cttgggggct 3350

 gcaccccaga catagctggc accagagcag ggtgctcagg tggtgggtgc 3400

 tcagggccct gccccaggcc actgggccgt tttgatgacc tcgaaggtca 3450

 caggcagaaa ataggagcag gatttcccct ggggaaaagt tctcctggga 3500

 catcttctgc tcttctgtac atttctagat gcaaataact ccttcaccag 3550

 gcagtgagtg gcgtaggctc tggagccagg ctgcctgggc tccaatgcca 3600

 gctctgccac ttgctagctg tgagactgtg gacaaaccac tcagcctctg 3650

 tgtgcctcag ttttcctatt tgtaaaatag aggccatagt ggtacctatt 3700

 ttgaagacta agtaaaagaa ttcaaataaa gagacttggc acagagtaag 3750

 tgctcagtaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 3848

<210> 5217
<211> 528
<212> PRT
<213> Homo sapien

<400> 5217
 Met Asp His Cys Gly Ala Leu Phe Leu Cys Leu Cys Leu Leu Thr
   1               5                  10                  15

 Leu Gln Asn Ala Thr Thr Glu Thr Trp Glu Glu Leu Leu Ser Tyr
                  20                  25                  30

 Met Glu Asn Met Gln Val Ser Arg Gly Arg Ser Ser Val Phe Ser
                  35                  40                  45

 Ser Arg Gln Leu His Gln Leu Glu Gln Met Leu Leu Asn Thr Ser
                  50                  55                  60

 Phe Pro Gly Tyr Asn Leu Thr Leu Gln Thr Pro Thr Ile Gln Ser
                  65                  70                  75

 Leu Ala Phe Lys Leu Ser Cys Asp Phe Ser Gly Leu Ser Leu Thr
                  80                  85                  90

 Ser Ala Thr Leu Lys Arg Val Pro Gln Ala Gly Gly Gln His Ala
                  95                 100                 105

 Arg Gly Gln His Ala Met Gln Phe Pro Ala Glu Leu Thr Arg Asp
                 110                 115                 120

 Ala Cys Lys Thr Arg Pro Arg Glu Leu Arg Leu Ile Cys Ile Tyr
                 125                 130                 135

 Phe Ser Asn Thr His Phe Phe Lys Asp Glu Asn Asn Ser Ser Leu
                 140                 145                 150

 Leu Asn Asn Tyr Val Leu Gly Ala Gln Leu Ser His Gly His Val
                 155                 160                 165

 Asn Asn Leu Arg Asp Pro Val Asn Ile Ser Phe Trp His Asn Gln
                 170                 175                 180

 Ser Leu Glu Gly Tyr Thr Leu Thr Cys Val Phe Trp Lys Glu Gly
                 185                 190                 195

 Ala Arg Lys Gln Pro Trp Gly Gly Trp Ser Pro Glu Gly Cys Arg
                 200                 205                 210

 Thr Glu Gln Pro Ser His Ser Gln Val Leu Cys Arg Cys Asn His
                 215                 220                 225

 Leu Thr Tyr Phe Ala Val Leu Met Gln Leu Ser Pro Ala Leu Val
                 230                 235                 240

 Pro Ala Glu Leu Leu Ala Pro Leu Thr Tyr Ile Ser Leu Val Gly
                 245                 250                 255

 Cys Ser Ile Ser Ile Val Ala Ser Leu Ile Thr Val Leu Leu His
                 260                 265                 270

 Phe His Phe Arg Lys Gln Ser Asp Ser Leu Thr Arg Ile His Met
                 275                 280                 285

 Asn Leu His Ala Ser Val Leu Leu Leu Asn Ile Ala Phe Leu Leu
                 290                 295                 300

 Ser Pro Ala Phe Ala Met Ser Pro Val Pro Gly Ser Ala Cys Thr
                 305                 310                 315

 Ala Leu Ala Ala Ala Leu His Tyr Ala Leu Leu Ser Cys Leu Thr
                 320                 325                 330

 Trp Met Ala Ile Glu Gly Phe Asn Leu Tyr Leu Leu Leu Gly Arg
                 335                 340                 345

 Val Tyr Asn Ile Tyr Ile Arg Arg Tyr Val Phe Lys Leu Gly Val
                 350                 355                 360

 Leu Gly Trp Gly Ala Pro Ala Leu Leu Val Leu Leu Ser Leu Ser
                 365                 370                 375

 Val Lys Ser Ser Val Tyr Gly Pro Cys Thr Ile Pro Val Phe Asp
                 380                 385                 390

 Ser Trp Glu Asn Gly Thr Gly Phe Gln Asn Met Ser Ile Cys Trp
                 395                 400                 405

 Val Arg Ser Pro Val Val His Ser Val Leu Val Met Gly Tyr Gly
                 410                 415                 420

 Gly Leu Thr Ser Leu Phe Asn Leu Val Val Leu Ala Trp Ala Leu
                 425                 430                 435

 Trp Thr Leu Arg Arg Leu Arg Glu Arg Ala Asp Ala Pro Ser Val
                 440                 445                 450

 Arg Ala Cys His Asp Thr Val Thr Val Leu Gly Leu Thr Val Leu
                 455                 460                 465

 Leu Gly Thr Thr Trp Ala Leu Ala Phe Phe Ser Phe Gly Val Phe
                 470                 475                 480

 Leu Leu Pro Gln Leu Phe Leu Phe Thr Ile Leu Asn Ser Leu Tyr
                 485                 490                 495

 Gly Phe Phe Leu Phe Leu Trp Phe Cys Ser Gln Arg Cys Arg Ser
                 500                 505                 510

 Glu Ala Glu Ala Lys Ala Gln Ile Glu Ala Phe Ser Ser Ser Gln
                 515                 520                 525

 Thr Thr Gln


<210> 5218
<211> 2292
<212> DNA
<213> Homo sapien

<400> 5218
 tctcagggct tcatacagga aatctattgc tgtgtcaagt tccagagaaa 50

 agcttctgtt cgtccaagtt actaaccagg ctaaaccaca tagacgtgaa 100

 ggaaggggct agaaggaagg gagtgcccca ctgttgatgg ggtaagagga 150

 tcctgtactg agaagttgac cagagagggt ctcaccatgc gcacagttcc 200

 ttctgtacct gtgtggagga aaagtactga gtgaagggca gaaaaagaga 250

 aaacagaaat gctctgccct tggagaactg ctaacctagg gctactgttg 300

 attttgacta tcttcttagt ggccgaagcg gagggtgctg ctcaaccaaa 350

 caactcatta atgctgcaaa ctagcaagga gaatcatgct ttagcttcaa 400

 gcagtttatg tatggatgaa aaacagatta cacagaacta ctcgaaagta 450

 ctcgcagaag ttaacacttc atggcctgta aagatggcta caaatgctgt 500

 gctttgttgc cctcctatcg cattaagaaa tttgatcata ataacatggg 550

 aaataatcct gagaggccag ccttcctgca caaaagccta caggaaagaa 600

 acaaatgaga ccaaggaaac caactgtact gatgagagaa taacctgggt 650

 ctccagacct gatcagaatt cggaccttca gattcgtcca gtggccatca 700

 ctcatgacgg gtattacaga tgcataatgg taacacctga tgggaatttc 750

 catcgtggat atcacctcca agtgttagtt acacctgaac tgaccctgtt 800

 tcaaaacagg aatagaactg cagtatgcaa ggcagttgca gggaagccag 850

 ctgcgcagat ctcctggatc ccagagggcg attgtgccac taagcaagaa 900

 tactggagca atggcacagt gactgttaag agtacatgcc actgggaggt 950

 ccacaatgtg tctaccgtga cctgccacgt ctcccatttg actggcaaca 1000

 agagtctgta catagagcta cttcctgttc caggtgccaa aaaatcagca 1050

 aaattatata ttccatatat catccttact attattattt tgaccatcgt 1100

 gggattcatt tggttgttga aagtcaatgg ctgcagaaaa tataaattga 1150

 ataaaacaga atctactcca gttgttgagg aggatgaaat gcagccctat 1200

 gccagctaca cagagaagaa caatcctctc tatgatacta caaacaaggt 1250

 gaaggcatct caggcattac aaagtgaagt tgacacagac ctccatactt 1300

 tataagttgt tggactctag taccaagaaa caacaacaaa cgagatacat 1350

 tataattact gtctgatttt cttacagttc tagaatgaag acttatattg 1400

 aaattaggtt ttccaaggtt cttagaagac attttaatgg attctcattc 1450

 atacccttgt ataattggaa tttttgattc ttagctgcta ccagctagtt 1500

 ctctgaagaa ctgatgttat tacaaagaaa atacatgccc atgaccaaat 1550

 attcaaattg tgcaggacag taaataatga aaaccaaatt tcctcaagaa 1600

 ataactgaag aaggagcaag tgtgaacagt ttcttgtgta tcctttcaga 1650

 atattttaat gtacatatga catgtgtata tgcctatggt atatgtgtca 1700

 atttatgtgt ccccttacat atacatgcac atatctttgt caaggcacca 1750

 gtgggaacaa tacactgcat tactgttcta tacatatgaa aacctaataa 1800

 tataagtctt agagatcatt ttatatcatg acaagtagag ctacctcatt 1850

 ctttttaatg gttatataaa attccattgt atagttatat cattatttaa 1900

 ttaaaaacaa ccctaatgat ggatatttag attcttttaa gttttgttta 1950

 tttcttttaa gttttgtttg tggtataaac aataccacat agaatgtttc 2000

 ttgttcatat atctctttgt ttttgagtat atctgtagga taactttctt 2050

 gagtggaatt gtcaggtcaa agggtttgtg cattttacta ttgatatata 2100

 tgttaaattg tgtcaaatat atatgtcaaa ttccctccaa cattgtttaa 2150

 atgtgccttt ccctaaattt ctattttaat aactgtacta ttcctgcttc 2200

 tacagttgcc actttctctt tttaatcaac cagattaaat atgatgtgag 2250

 attataataa gaattatact atttaataaa aatggattta ta 2292

<210> 5219
<211> 348
<212> PRT
<213> Homo sapien

<400> 5219
 Met Leu Cys Pro Trp Arg Thr Ala Asn Leu Gly Leu Leu Leu Ile
   1               5                  10                  15

 Leu Thr Ile Phe Leu Val Ala Glu Ala Glu Gly Ala Ala Gln Pro
                  20                  25                  30

 Asn Asn Ser Leu Met Leu Gln Thr Ser Lys Glu Asn His Ala Leu
                  35                  40                  45

 Ala Ser Ser Ser Leu Cys Met Asp Glu Lys Gln Ile Thr Gln Asn
                  50                  55                  60

 Tyr Ser Lys Val Leu Ala Glu Val Asn Thr Ser Trp Pro Val Lys
                  65                  70                  75

 Met Ala Thr Asn Ala Val Leu Cys Cys Pro Pro Ile Ala Leu Arg
                  80                  85                  90

 Asn Leu Ile Ile Ile Thr Trp Glu Ile Ile Leu Arg Gly Gln Pro
                  95                 100                 105

 Ser Cys Thr Lys Ala Tyr Arg Lys Glu Thr Asn Glu Thr Lys Glu
                 110                 115                 120

 Thr Asn Cys Thr Asp Glu Arg Ile Thr Trp Val Ser Arg Pro Asp
                 125                 130                 135

 Gln Asn Ser Asp Leu Gln Ile Arg Pro Val Ala Ile Thr His Asp
                 140                 145                 150

 Gly Tyr Tyr Arg Cys Ile Met Val Thr Pro Asp Gly Asn Phe His
                 155                 160                 165

 Arg Gly Tyr His Leu Gln Val Leu Val Thr Pro Glu Leu Thr Leu
                 170                 175                 180

 Phe Gln Asn Arg Asn Arg Thr Ala Val Cys Lys Ala Val Ala Gly
                 185                 190                 195

 Lys Pro Ala Ala Gln Ile Ser Trp Ile Pro Glu Gly Asp Cys Ala
                 200                 205                 210

 Thr Lys Gln Glu Tyr Trp Ser Asn Gly Thr Val Thr Val Lys Ser
                 215                 220                 225

 Thr Cys His Trp Glu Val His Asn Val Ser Thr Val Thr Cys His
                 230                 235                 240

 Val Ser His Leu Thr Gly Asn Lys Ser Leu Tyr Ile Glu Leu Leu
                 245                 250                 255

 Pro Val Pro Gly Ala Lys Lys Ser Ala Lys Leu Tyr Ile Pro Tyr
                 260                 265                 270

 Ile Ile Leu Thr Ile Ile Ile Leu Thr Ile Val Gly Phe Ile Trp
                 275                 280                 285

 Leu Leu Lys Val Asn Gly Cys Arg Lys Tyr Lys Leu Asn Lys Thr
                 290                 295                 300

 Glu Ser Thr Pro Val Val Glu Glu Asp Glu Met Gln Pro Tyr Ala
                 305                 310                 315

 Ser Tyr Thr Glu Lys Asn Asn Pro Leu Tyr Asp Thr Thr Asn Lys
                 320                 325                 330

 Val Lys Ala Ser Gln Ala Leu Gln Ser Glu Val Asp Thr Asp Leu
                 335                 340                 345

 His Thr Leu


<210> 5220
<211> 2270
<212> DNA
<213> Homo sapien

<400> 5220
 ggcacgaggt tttcctcggc gcttctccat ggaggaggcg gtgcgaacgg 50

 cttcagcccc gaatgctcgc atctcccact ggacggcgac gaaggcggtg 100

 gccgtgcgag cgcaggactg ggcggcctgt gtgggggtgt gagccgcggt 150

 gcccaaggct gcgccggcga ggggaagccg cgcggccggc cggccgacta 200

 gggtttgaag actgcttcat tctgcctcta gtaccagcgg tttctctgtt 250

 ctgtgatcaa tgtgattcac aggaactcct taagtaacaa acgaaatgag 300

 ccaggggcgt ggaaaatatg acttctatat tggtctggga ttggctatga 350

 gctccagcat tttcattgga ggaagtttca ttttgaaaaa aaagggcctc 400

 cttcgacttg ccaggaaagg ctctatgaga gcaggtcaag gtggccatgc 450

 atatcttaag gaatggttgt ggtgggctgg actgctgtca atgggagctg 500

 gtgaggtggc caacttcgct gcgtatgcgt ttgcaccagc cactctagtg 550

 actccactag gagctctcag cgtgctagta agtgccattc tttcttcata 600

 ctttctcaat gaaagactta atcttcatgg gaaaattggg tgtttgctaa 650

 gtattctagg atctacagtt atggtcattc atgctccaaa ggaagaggag 700

 attgagactt taaatgaaat gtctcacaag ctaggtgatc caggttttgt 750

 ggtctttgca acccttgtgg tcattgtggc cttgatatta atcttcgtgg 800

 tgggtcctcg ccatggacag acaaacattc ttgtgtacat aacaatctgc 850

 tctgtaatcg gcgcgttttc agtctcctgt gtgaagggcc tgggcattgc 900

 tatcaaggag ctgtttgcag ggaagcctgt gctgcggcat cccctggctt 950

 ggattctgct gctgagcctc atcgtctgtg tgagcacaca gattaattac 1000

 ctaaataggg ccctggatat attcaacact tccattgtga ctccaatata 1050

 ttatgtattc tttacaacat cagttttaac ttgttcagct attcttttta 1100

 aggagtggca agatatgcct gttgacgatg tcattggtac tttgagtggc 1150

 ttctttacaa tcattgtggg gatattcttg ttgcatgcct ttaaagacgt 1200

 cggctttagt ctagcaagtc tgcctgtgtc ttttcgaaaa gacgagaaag 1250

 caatgaatgg caatctctct aatatgtatg aagttcttaa taataatgaa 1300

 gaaagcttaa cctgtggaat cgaacaacac actggtgaaa atgtctcccg 1350

 aagaaatgga aatctgacag ctttttaaga aaggtgtaat taaaggttaa 1400

 tctgtgattg ttatgaagtg aatttgaata tcatcagaat gtgtctgaaa 1450

 aaacattgtc ctcaaataat gttctttaaa ggcaatcttt ttaaagattt 1500

 cactaatttg gaccaagaaa ttacttttct tgtatttaaa caaacaatgg 1550

 tagctcacta aaatgacctc agcacatgac gatttctatt aacattttat 1600

 tgttgtagaa gtattttaca ttttcatccc ttctccaaaa gccgaatgca 1650

 ctaatgacag ttttaagtct atgaaaatgc tttatttttt cattggtgat 1700

 gaaagtctga aatgtgcatt tgtcatcccc actccatcaa tccctgacca 1750

 tgtaaggctt ttttatttta aaaaaacaga gttatcccaa tacattatcc 1800

 tgtgatttac cttacctaca aaagtggctc ctgtttgttt gatgatgatt 1850

 ggttttattt ttgaaatatt tattaaggga aaactaagtt actgaatgaa 1900

 ggaacctctt tcttacaaaa caaaaaaaag ggcagaaatc accccaagga 1950

 acgatttctc aggttgagat gatcaccgtg aatccggctt cctctgagca 2000

 ttcgatggcc ttagcacctc atcaagccag cacatcctgc ctgctgttgc 2050

 agcctggctg ggtttattct tcagttaccc taatcccatg atgcctggaa 2100

 ccttgattac cgttttacat cagctcttgt acttttcagt atattttcat 2150

 aatgagttat attgtcattt agactttgaa cagctctggg aaatagaaga 2200

 ctagggttgt ttcttaaatt tagctcatgt tataataaaa agttgaaatg 2250

 aaaaaaaaaa aaaaaaaaaa 2270

<210> 5221
<211> 360
<212> PRT
<213> Homo sapien

<400> 5221
 Met Ser Gln Gly Arg Gly Lys Tyr Asp Phe Tyr Ile Gly Leu Gly
   1               5                  10                  15

 Leu Ala Met Ser Ser Ser Ile Phe Ile Gly Gly Ser Phe Ile Leu
                  20                  25                  30

 Lys Lys Lys Gly Leu Leu Arg Leu Ala Arg Lys Gly Ser Met Arg
                  35                  40                  45

 Ala Gly Gln Gly Gly His Ala Tyr Leu Lys Glu Trp Leu Trp Trp
                  50                  55                  60

 Ala Gly Leu Leu Ser Met Gly Ala Gly Glu Val Ala Asn Phe Ala
                  65                  70                  75

 Ala Tyr Ala Phe Ala Pro Ala Thr Leu Val Thr Pro Leu Gly Ala
                  80                  85                  90

 Leu Ser Val Leu Val Ser Ala Ile Leu Ser Ser Tyr Phe Leu Asn
                  95                 100                 105

 Glu Arg Leu Asn Leu His Gly Lys Ile Gly Cys Leu Leu Ser Ile
                 110                 115                 120

 Leu Gly Ser Thr Val Met Val Ile His Ala Pro Lys Glu Glu Glu
                 125                 130                 135

 Ile Glu Thr Leu Asn Glu Met Ser His Lys Leu Gly Asp Pro Gly
                 140                 145                 150

 Phe Val Val Phe Ala Thr Leu Val Val Ile Val Ala Leu Ile Leu
                 155                 160                 165

 Ile Phe Val Val Gly Pro Arg His Gly Gln Thr Asn Ile Leu Val
                 170                 175                 180

 Tyr Ile Thr Ile Cys Ser Val Ile Gly Ala Phe Ser Val Ser Cys
                 185                 190                 195

 Val Lys Gly Leu Gly Ile Ala Ile Lys Glu Leu Phe Ala Gly Lys
                 200                 205                 210

 Pro Val Leu Arg His Pro Leu Ala Trp Ile Leu Leu Leu Ser Leu
                 215                 220                 225

 Ile Val Cys Val Ser Thr Gln Ile Asn Tyr Leu Asn Arg Ala Leu
                 230                 235                 240

 Asp Ile Phe Asn Thr Ser Ile Val Thr Pro Ile Tyr Tyr Val Phe
                 245                 250                 255

 Phe Thr Thr Ser Val Leu Thr Cys Ser Ala Ile Leu Phe Lys Glu
                 260                 265                 270

 Trp Gln Asp Met Pro Val Asp Asp Val Ile Gly Thr Leu Ser Gly
                 275                 280                 285

 Phe Phe Thr Ile Ile Val Gly Ile Phe Leu Leu His Ala Phe Lys
                 290                 295                 300

 Asp Val Gly Phe Ser Leu Ala Ser Leu Pro Val Ser Phe Arg Lys
                 305                 310                 315

 Asp Glu Lys Ala Met Asn Gly Asn Leu Ser Asn Met Tyr Glu Val
                 320                 325                 330

 Leu Asn Asn Asn Glu Glu Ser Leu Thr Cys Gly Ile Glu Gln His
                 335                 340                 345

 Thr Gly Glu Asn Val Ser Arg Arg Asn Gly Asn Leu Thr Ala Phe
                 350                 355                 360

<210> 5222
<211> 2534
<212> DNA
<213> Homo sapien

<400> 5222
 gcagaggtga gtgccgggct cggcgctctg ctcctggagc tcccgcggga 50

 ctgcctgggg acagggactg ctgtggcgct cggccctcca ctgcggacct 100

 ctcctgagtg ggtgcgccga gtcatggagg gcgcagagct ggccgggaag 150

 atcctttcca cctggctgac gctggttctc ggcttcatcc ttttaccttc 200

 ggtcttcgga gtgtctctgg gcatctccga gatctacatg aagatcctag 250

 tgaaaacttt agagtgggcc acaatacgaa ttgaaaaagg aaccccaaag 300

 gagtcgattc ttaaaaactc tgcttctgtt ggtattatcc aaagagatga 350

 gtcacccatg gaaaaagggc tctctggtct acgaggaagg gactttgagc 400

 tgtctgacgt gttttatttc tccaagaagg gattggaagc cattgtagaa 450

 gatgaagtga cccagaggtt ttcctcagag gagctagtgt catggaatct 500

 cctcacaaga accaatgtaa atttccagta catcagtctg cggctcacta 550

 tggtgtgggt gctgggcgtc atagtgcgct attgtgtcct actgcctctg 600

 agggttacct tggctttcat tgggatcagt ttgctggtta taggaactac 650

 actggttggg cagctgccag acagcagcct caaaaactgg ctgagtgaac 700

 tggtccatct gacttgctgc cggatctgtg tgcgagccct ctctggtacc 750

 attcattatc ataacaagca gtacagaccc cagaagggag gcatttgtgt 800

 tgccaaccat acttccccca ttgatgtttt aatcttgaca acggatggat 850

 gttatgctat ggttggccag gttcatggcg gcttgatggg aattattcag 900

 agagctatgg tcaaggcttg tcctcatgtc tggtttgaac gctcagaaat 950

 gaaggatcga cacctggtta ctaagagact aaaagaacat attgctgata 1000

 agaagaaact acccatacta atttttcctg aaggaacttg catcaacaat 1050

 acttcagtca tgatgtttaa aaaggggagc tttgaaattg gaggaaccat 1100

 acatccagtt gcaattaagt ataaccctca gttcggtgat gcattttgga 1150

 acagtagtaa atacaacatg gtgagctacc tgcttcgaat gatgaccagc 1200

 tgggccatcg tctgtgacgt gtggtacatg ccccccatga ccagagagga 1250

 aggagaagat gcagtccagt ttgctaacag ggttaagtct gctattgcta 1300

 tacaaggagg cctgactgaa cttccctggg atggaggact aaagagagca 1350

 aaggtgaagg acatctttaa ggaagagcag cagaaaaatt acagcaagat 1400

 gattgtgggc aatggatctc tcagctaaga ggacggatga cagcctttag 1450

 atctagaact agcccttaga aatggaatgg ctttttttgt tttgttttgt 1500

 tttattgttt tgtttttatt attgttaatc ttttctacag aatgattgtc 1550

 tctacctctt tatgccagag gcagaaccta caggtgccct ttttggcttt 1600

 tgttgttgtt gtaacattag ccccatggat tgtaaggtgg tttactgagt 1650

 taaaacagat tctgcttttg taaaatgatg gcatcactgt ggactgaatg 1700

 aaatatttgt atagaaaaaa gtgcttgaaa agtgtgtttg gaactcatcg 1750

 atagggtaat tctccaaaaa tgcccaaact ctttttctgt aattagcctt 1800

 gccactttct tcagtcactt aaatggtgag attacacatc agtgcaagat 1850

 gaccattatg gttatggtct actgcaaggt tgaaaggaaa aatggaggat 1900

 tgtatttagg aaaagggaca actttgtggc cacctgctct gaaagtcaaa 1950

 aggaaatgta aattagtgtc attagtgtgt tggaagagaa atactattca 2000

 gtaagcttcg ccaaagaaaa gtgagtcaaa gttaatgtgt gtgcgcattt 2050

 atatgtaggc agctcgtaga ccacatttta accagcaact ggtaacaaag 2100

 agcttagttt tccttgtttg aatgctgtag atctgtacct agtacccctc 2150

 ccatctactg atttgtttgt ttttgtaacc aaacacattt tcagatagaa 2200

 ggagccttaa aaaaaaaaaa tcacattgag taacttcagt atgaatgaat 2250

 gagagtgtgt ggagctaccc ctcaccctcc acccctttgt gctttttatt 2300

 cccgaatttt cccagtctct taaacagaaa aatgactgat ataattatct 2350

 tttggaaact gagccttaat tttttttaga gggggaaata agttttcccc 2400

 aactcacaca gcataagcaa tgtttgacag caatataatg ccgttgtaaa 2450

 ctactgagag tattgtatct gttctggtaa ccatgtacag aatgtgaaac 2500

 tgtcttatga atataaataa attctatatt tcta 2534

<210> 5223
<211> 434
<212> PRT
<213> Homo sapien

<400> 5223
 Met Glu Gly Ala Glu Leu Ala Gly Lys Ile Leu Ser Thr Trp Leu
   1               5                  10                  15

 Thr Leu Val Leu Gly Phe Ile Leu Leu Pro Ser Val Phe Gly Val
                  20                  25                  30

 Ser Leu Gly Ile Ser Glu Ile Tyr Met Lys Ile Leu Val Lys Thr
                  35                  40                  45

 Leu Glu Trp Ala Thr Ile Arg Ile Glu Lys Gly Thr Pro Lys Glu
                  50                  55                  60

 Ser Ile Leu Lys Asn Ser Ala Ser Val Gly Ile Ile Gln Arg Asp
                  65                  70                  75

 Glu Ser Pro Met Glu Lys Gly Leu Ser Gly Leu Arg Gly Arg Asp
                  80                  85                  90

 Phe Glu Leu Ser Asp Val Phe Tyr Phe Ser Lys Lys Gly Leu Glu
                  95                 100                 105

 Ala Ile Val Glu Asp Glu Val Thr Gln Arg Phe Ser Ser Glu Glu
                 110                 115                 120

 Leu Val Ser Trp Asn Leu Leu Thr Arg Thr Asn Val Asn Phe Gln
                 125                 130                 135

 Tyr Ile Ser Leu Arg Leu Thr Met Val Trp Val Leu Gly Val Ile
                 140                 145                 150

 Val Arg Tyr Cys Val Leu Leu Pro Leu Arg Val Thr Leu Ala Phe
                 155                 160                 165

 Ile Gly Ile Ser Leu Leu Val Ile Gly Thr Thr Leu Val Gly Gln
                 170                 175                 180

 Leu Pro Asp Ser Ser Leu Lys Asn Trp Leu Ser Glu Leu Val His
                 185                 190                 195

 Leu Thr Cys Cys Arg Ile Cys Val Arg Ala Leu Ser Gly Thr Ile
                 200                 205                 210

 His Tyr His Asn Lys Gln Tyr Arg Pro Gln Lys Gly Gly Ile Cys
                 215                 220                 225

 Val Ala Asn His Thr Ser Pro Ile Asp Val Leu Ile Leu Thr Thr
                 230                 235                 240

 Asp Gly Cys Tyr Ala Met Val Gly Gln Val His Gly Gly Leu Met
                 245                 250                 255

 Gly Ile Ile Gln Arg Ala Met Val Lys Ala Cys Pro His Val Trp
                 260                 265                 270

 Phe Glu Arg Ser Glu Met Lys Asp Arg His Leu Val Thr Lys Arg
                 275                 280                 285

 Leu Lys Glu His Ile Ala Asp Lys Lys Lys Leu Pro Ile Leu Ile
                 290                 295                 300

 Phe Pro Glu Gly Thr Cys Ile Asn Asn Thr Ser Val Met Met Phe
                 305                 310                 315

 Lys Lys Gly Ser Phe Glu Ile Gly Gly Thr Ile His Pro Val Ala
                 320                 325                 330

 Ile Lys Tyr Asn Pro Gln Phe Gly Asp Ala Phe Trp Asn Ser Ser
                 335                 340                 345

 Lys Tyr Asn Met Val Ser Tyr Leu Leu Arg Met Met Thr Ser Trp
                 350                 355                 360

 Ala Ile Val Cys Asp Val Trp Tyr Met Pro Pro Met Thr Arg Glu
                 365                 370                 375

 Glu Gly Glu Asp Ala Val Gln Phe Ala Asn Arg Val Lys Ser Ala
                 380                 385                 390

 Ile Ala Ile Gln Gly Gly Leu Thr Glu Leu Pro Trp Asp Gly Gly
                 395                 400                 405

 Leu Lys Arg Ala Lys Val Lys Asp Ile Phe Lys Glu Glu Gln Gln
                 410                 415                 420

 Lys Asn Tyr Ser Lys Met Ile Val Gly Asn Gly Ser Leu Ser
                 425                 430

<210> 5224
<211> 2610
<212> DNA
<213> Homo sapien

<400> 5224
 ggactgttaa ctgtttctgg caaacatgaa gtcaggcctc tggtatttct 50

 ttctcttctg cttgcgcatt aaagttttaa caggagaaat caatggttct 100

 gccaattatg agatgtttat atttcacaac ggaggtgtac aaattttatg 150

 caaatatcct gacattgtcc agcaatttaa aatgcagttg ctgaaagggg 200

 ggcaaatact ctgcgatctc actaagacaa aaggaagtgg aaacacagtg 250

 tccattaaga gtctgaaatt ctgccattct cagttatcca acaacagtgt 300

 ctcttttttt ctatacaact tggaccattc tcatgccaac tattacttct 350

 gcaacctatc aatttttgat cctcctcctt ttaaagtaac tcttacagga 400

 ggatatttgc atatttatga atcacaactt tgttgccagc tgaagttctg 450

 gttacccata ggatgtgcag cctttgttgt agtctgcatt ttgggatgca 500

 tacttatttg ttggcttaca aaaaagaagt attcatccag tgtgcacgac 550

 cctaacggtg aatacatgtt catgagagca gtgaacacag ccaaaaaatc 600

 tagactcaca gatgtgaccc tataatatgg aactctggca cccaggcatg 650

 aagcacgttg gccagttttc ctcaacttga agtgcaagat tctcttattt 700

 ccgggaccac ggagagtctg acttaactac atacatcttc tgctggtgtt 750

 ttgttcaatc tggaagaatg actgtatcag tcaatgggga ttttaacaga 800

 ctgccttggt actgccgagt cctctcaaaa caaacaccct cttgcaacca 850

 gctttggaga aagcccagct cctgtgtgct cactgggagt ggaatccctg 900

 tctccacatc tgctcctagc agtgcatcag ccagtaaaac aaacacattt 950

 acaagaaaaa tgttttaaag atgccagggg tactgaatct gcaaagcaaa 1000

 tgagcagcca aggaccagca tctgtccgca tttcactatc atactacctc 1050

 ttctttctgt agggatgaga attcctcttt taatcagtca agggagatgc 1100

 ttcaaagctg gagctatttt atttctgaga tgttgatgtg aactgtacat 1150

 tagtacatac tcagtactct ccttcaattg ctgaacccca gttgaccatt 1200

 ttaccaagac tttagatgct ttcttgtgcc ctcaattttc tttttaaaaa 1250

 tacttctaca tgactgcttg acagcccaac agccactctc aatagagagc 1300

 tatgtcttac attctttcct ctgctgctca atagttttat atatctatgc 1350

 atacatatat acacacatat gtatataaaa ttcataatga atatatttgc 1400

 ctatattctc cctacaagaa tatttttgct ccagaaagac atgttctttt 1450

 ctcaaattca gttaaaatgg tttactttgt tcaagttagt ggtaggaaac 1500

 attgcccgga attgaaagca aatttatttt attatcctat tttctaccat 1550

 tatctatgtt ttcatggtgc tattaattac aagtttagtt ctttttgtag 1600

 atcatattaa aattgcaaac aaaatcatct ttaatgggcc agcattctca 1650

 tggggtagag cagaatattc atttagcctg aaagctgcag ttactatagg 1700

 ttgctgtcag actataccca tggtgcctct gggcttgaca ggtcaaaatg 1750

 gtccccatca gcctggagca gccctccaga cctgggtgga attccagggt 1800

 tgagagactc ccctgagcca gaggccacta ggtattcttg ctcccagagg 1850

 ctgaagtcac cctgggaatc acagtggtct acctgcattc ataattccag 1900

 gatctgtgaa gagcacatat gtgtcagggc acaattccct ctcataaaaa 1950

 ccacacagcc tggaaattgg ccctggccct tcaagatagc cttctttaga 2000

 atatgatttg gctagaaaga ttcttaaata tgtggaatat gattattctt 2050

 agctggaata ttttctctac ttcctgtctg catgcccaag gcttctgaag 2100

 cagccaatgt cgatgcaaca acatttgtaa ctttaggtaa actgggatta 2150

 tgttgtagtt taacattttg taactgtgtg cttatagttt acaagtgaga 2200

 cccgatatgt cattatgcat acttatatta tcttaagcat gtgtaatgct 2250

 ggatgtgtac agtacagtac ttaacttgta atttgaatct agtatggtgt 2300

 tctgttttca gctgacttgg acaacctgac tggctttgca caggtgttcc 2350

 ctgagttgtt tgcaggtttc tgtgtgtggg gtggggtatg gggaggagaa 2400

 ccttcatggt ggcccacctg gcctggttgt ccaagctgtg cctcgacaca 2450

 tcctcatccc aagcatggga cacctcaaga tgaataataa ttcacaaaat 2500

 ttctgtgaaa tcaaatccag ttttaagagg agccacttat caaagagatt 2550

 ttaacagtag taagaaggca aagaataaac atttgatatt cagcaactga 2600

 aaaaaaaaaa 2610

<210> 5225
<211> 199
<212> PRT
<213> Homo sapien

<400> 5225
 Met Lys Ser Gly Leu Trp Tyr Phe Phe Leu Phe Cys Leu Arg Ile
   1               5                  10                  15

 Lys Val Leu Thr Gly Glu Ile Asn Gly Ser Ala Asn Tyr Glu Met
                  20                  25                  30

 Phe Ile Phe His Asn Gly Gly Val Gln Ile Leu Cys Lys Tyr Pro
                  35                  40                  45

 Asp Ile Val Gln Gln Phe Lys Met Gln Leu Leu Lys Gly Gly Gln
                  50                  55                  60

 Ile Leu Cys Asp Leu Thr Lys Thr Lys Gly Ser Gly Asn Thr Val
                  65                  70                  75

 Ser Ile Lys Ser Leu Lys Phe Cys His Ser Gln Leu Ser Asn Asn
                  80                  85                  90

 Ser Val Ser Phe Phe Leu Tyr Asn Leu Asp His Ser His Ala Asn
                  95                 100                 105

 Tyr Tyr Phe Cys Asn Leu Ser Ile Phe Asp Pro Pro Pro Phe Lys
                 110                 115                 120

 Val Thr Leu Thr Gly Gly Tyr Leu His Ile Tyr Glu Ser Gln Leu
                 125                 130                 135

 Cys Cys Gln Leu Lys Phe Trp Leu Pro Ile Gly Cys Ala Ala Phe
                 140                 145                 150

 Val Val Val Cys Ile Leu Gly Cys Ile Leu Ile Cys Trp Leu Thr
                 155                 160                 165

 Lys Lys Lys Tyr Ser Ser Ser Val His Asp Pro Asn Gly Glu Tyr
                 170                 175                 180

 Met Phe Met Arg Ala Val Asn Thr Ala Lys Lys Ser Arg Leu Thr
                 185                 190                 195

 Asp Val Thr Leu


<210> 5226
<211> 3024
<212> DNA
<213> Homo sapien

<400> 5226
 ggggtcctgc agcctcccga gtgcggagag gcggggccgc ccgctgccgc 50

 ccggctgcct gcgccccctc ccgcggcccc ggctctggga gcggggcgcc 100

 ccgcgcgcgg gcacacggcg gccagagcgc cgaggcggta ccttcagcct 150

 gcaatgagag gaacccggga gagcccccgg gagccagcga agagcttggc 200

 tgctgcgtcc agggctgctg ctgccgccgc ggctgcttga aactcctcaa 250

 agttgagagc cggctagagg gtgccgcccg ccgggagccg gagggaaagg 300

 aagtcgggag gtgcaagagt gacagacacg gacagacgga cgcgcagacc 350

 ttcggaaggc actgcgtagg cagcctcccc ggagcccacg aggctcccca 400

 gcaccgttca ctggtgggag gctgagccgg tggaaaagac accgggaaga 450

 gactcagagg cgaccataat gtcgttacgt gtacacactc tgcccaccct 500

 gcttggagcc gtcgtcagac cgggctgcag ggagctgctg tgtttgctga 550

 tgatcacagt gactgtgggc cctggtgcct ctggggtgtg ccccaccgct 600

 tgcatctgtg ccactgacat cgtcagctgc accaacaaaa acctgtccaa 650

 ggtgcctggg aaccttttca gactgattaa gagactggac ctgagttata 700

 acagaattgg gcttctggat tctgagtgga ttccagtatc gtttgcaaag 750

 ctgaacaccc taattcttcg tcataacaac atcaccagca tttccacggg 800

 cagtttttcc acaactccaa atttgaagtg tcttgactta tcgtccaata 850

 agctgaagac ggtgaaaaat gctgtattcc aagagttgaa ggttctggaa 900

 gtgcttctgc tttacaacaa tcacatatcc tatctcgatc cttcagcgtt 950

 tggagggctc tcccagttgc agaaactcta cttaagtgga aattttctca 1000

 cacagtttcc gatggatttg tatgttggaa ggttcaagct ggcagaactg 1050

 atgtttttag atgtttctta taaccgaatt ccttccatgc caatgcacca 1100

 cataaattta gtgccaggaa aacagctgag aggcatctac cttcatggaa 1150

 acccatttgt ctgtgactgt tccctgtact ccttgctggt cttttggtat 1200

 cgtaggcact ttagctcagt gatggatttt aagaacgatt acacctgtcg 1250

 cctgtggtct gactccaggc actcgcgtca ggtacttctg ctccaggata 1300

 gctttatgaa ttgctctgac agcatcatca atggttcctt tcgtgcgctt 1350

 ggctttattc atgaggctca ggtcggggaa agactgatgg tccactgtga 1400

 cagcaagaca ggtaatgcaa atacggattt catctgggtg ggtccagata 1450

 acagactgct agagccggat aaagagatgg aaaactttta cgtgtttcac 1500

 aatggaagtc tggttataga aagccctcgt tttgaggatg ctggagtgta 1550

 ttcttgtatc gcaatgaata agcaacgcct gttaaatgaa actgtggacg 1600

 tcacaataaa tgtgagcaat ttcactgtaa gcagatccca tgctcatgag 1650

 gcatttaaca cagcttttac cactcttgct gcttgcgtgg ccagtatcgt 1700

 tttggtactt ttgtacctct atctgactcc atgcccctgc aagtgtaaaa 1750

 ccaagagaca gaaaaatatg ctacaccaaa gcaatgccca ttcatcgatt 1800

 ctcagtcctg gccctgctag tgatgcctcc gctgatgaac ggaaggcagg 1850

 tgcaggtaaa agagtggtgt ttttggaacc cctgaaggat actgcagcag 1900

 ggcagaacgg gaaagtcagg ctctttccca gcgaggcagt gatagctgag 1950

 ggcatcctaa agtccacgag ggggaaatct gactcagatt cagtcaattc 2000

 agtgttttct gacacacctt ttgtggcgtc cacttaattt gtgcctatat 2050

 ttgtatgatg tcataattta atctgttcat atttaacttt gtgtgtggtc 2100

 tgcaaaataa acagcaggac agaaattgtg ttgttttgtt ctttgaaata 2150

 caaccaaatt ctcttaaaat gattggtagg aaatgaggta aagtacttca 2200

 gttcctcaat gtgccagaga aagatggggt tgttttccaa agtttaagtt 2250

 ctagatcaca atatcttagc ttttagcact attggtaatt tcagagtagg 2300

 cccaaaggtg atatgactcc cattgtccct ttatttagga tattgaaaga 2350

 aaaaataaac tttatgtatt agtgtccttt aaaaatagac tttgctaact 2400

 tactagtacc agagttattt taaagaaaaa cactagtgtc caatttcatt 2450

 tttaaaagat gtagaaagaa gaatcaagca tcaattaatt ataaagccta 2500

 aagcaaagtt agatttgggg gttattcagc caaaattacc gttttagacc 2550

 agaatgaata gactacactg ataaaatgta ctggataatg ccacatccta 2600

 tatggtgtta tagaaatagt gcaaggaaag tacatttgtt tgcctgtctt 2650

 ttcattttgt acattcttcc cattctgtat tcttgtacaa aagatctcat 2700

 tgaaaattta aagtcatcat aatttgttgc cataaatatg taagtgtcaa 2750

 taccaaaatg tctgagtaac ttcttaaatc cctgttctag caaactaata 2800

 ttggttcatg tgcttgtgta tatgtaaatc ttaaattatg tgaactatta 2850

 aatagaccct actgtactgt gctttggaca tttgaattaa tgtaaatata 2900

 tgtaatctgt gacttgatat tttgttttat ttggctattt aaaaacataa 2950

 atctaaaatg tcttatgtta tcagattatg ctattttgta taaagcacca 3000

 ctgatagcaa aaaaaaaaaa aaaa 3024

<210> 5227
<211> 522
<212> PRT
<213> Homo sapien

<400> 5227
 Met Ser Leu Arg Val His Thr Leu Pro Thr Leu Leu Gly Ala Val
   1               5                  10                  15

 Val Arg Pro Gly Cys Arg Glu Leu Leu Cys Leu Leu Met Ile Thr
                  20                  25                  30

 Val Thr Val Gly Pro Gly Ala Ser Gly Val Cys Pro Thr Ala Cys
                  35                  40                  45

 Ile Cys Ala Thr Asp Ile Val Ser Cys Thr Asn Lys Asn Leu Ser
                  50                  55                  60

 Lys Val Pro Gly Asn Leu Phe Arg Leu Ile Lys Arg Leu Asp Leu
                  65                  70                  75

 Ser Tyr Asn Arg Ile Gly Leu Leu Asp Ser Glu Trp Ile Pro Val
                  80                  85                  90

 Ser Phe Ala Lys Leu Asn Thr Leu Ile Leu Arg His Asn Asn Ile
                  95                 100                 105

 Thr Ser Ile Ser Thr Gly Ser Phe Ser Thr Thr Pro Asn Leu Lys
                 110                 115                 120

 Cys Leu Asp Leu Ser Ser Asn Lys Leu Lys Thr Val Lys Asn Ala
                 125                 130                 135

 Val Phe Gln Glu Leu Lys Val Leu Glu Val Leu Leu Leu Tyr Asn
                 140                 145                 150

 Asn His Ile Ser Tyr Leu Asp Pro Ser Ala Phe Gly Gly Leu Ser
                 155                 160                 165

 Gln Leu Gln Lys Leu Tyr Leu Ser Gly Asn Phe Leu Thr Gln Phe
                 170                 175                 180

 Pro Met Asp Leu Tyr Val Gly Arg Phe Lys Leu Ala Glu Leu Met
                 185                 190                 195

 Phe Leu Asp Val Ser Tyr Asn Arg Ile Pro Ser Met Pro Met His
                 200                 205                 210

 His Ile Asn Leu Val Pro Gly Lys Gln Leu Arg Gly Ile Tyr Leu
                 215                 220                 225

 His Gly Asn Pro Phe Val Cys Asp Cys Ser Leu Tyr Ser Leu Leu
                 230                 235                 240

 Val Phe Trp Tyr Arg Arg His Phe Ser Ser Val Met Asp Phe Lys
                 245                 250                 255

 Asn Asp Tyr Thr Cys Arg Leu Trp Ser Asp Ser Arg His Ser Arg
                 260                 265                 270

 Gln Val Leu Leu Leu Gln Asp Ser Phe Met Asn Cys Ser Asp Ser
                 275                 280                 285

 Ile Ile Asn Gly Ser Phe Arg Ala Leu Gly Phe Ile His Glu Ala
                 290                 295                 300

 Gln Val Gly Glu Arg Leu Met Val His Cys Asp Ser Lys Thr Gly
                 305                 310                 315

 Asn Ala Asn Thr Asp Phe Ile Trp Val Gly Pro Asp Asn Arg Leu
                 320                 325                 330

 Leu Glu Pro Asp Lys Glu Met Glu Asn Phe Tyr Val Phe His Asn
                 335                 340                 345

 Gly Ser Leu Val Ile Glu Ser Pro Arg Phe Glu Asp Ala Gly Val
                 350                 355                 360

 Tyr Ser Cys Ile Ala Met Asn Lys Gln Arg Leu Leu Asn Glu Thr
                 365                 370                 375

 Val Asp Val Thr Ile Asn Val Ser Asn Phe Thr Val Ser Arg Ser
                 380                 385                 390

 His Ala His Glu Ala Phe Asn Thr Ala Phe Thr Thr Leu Ala Ala
                 395                 400                 405

 Cys Val Ala Ser Ile Val Leu Val Leu Leu Tyr Leu Tyr Leu Thr
                 410                 415                 420

 Pro Cys Pro Cys Lys Cys Lys Thr Lys Arg Gln Lys Asn Met Leu
                 425                 430                 435

 His Gln Ser Asn Ala His Ser Ser Ile Leu Ser Pro Gly Pro Ala
                 440                 445                 450

 Ser Asp Ala Ser Ala Asp Glu Arg Lys Ala Gly Ala Gly Lys Arg
                 455                 460                 465

 Val Val Phe Leu Glu Pro Leu Lys Asp Thr Ala Ala Gly Gln Asn
                 470                 475                 480

 Gly Lys Val Arg Leu Phe Pro Ser Glu Ala Val Ile Ala Glu Gly
                 485                 490                 495

 Ile Leu Lys Ser Thr Arg Gly Lys Ser Asp Ser Asp Ser Val Asn
                 500                 505                 510

 Ser Val Phe Ser Asp Thr Pro Phe Val Ala Ser Thr
                 515                 520

<210> 5228
<211> 6225
<212> DNA
<213> Homo sapien

<400> 5228
 gagggacttc tgtaaggcgg cacgaccaca ccaaataaca gcagcagagg 50

 gaggtggggg agagggaaat aaaggggagt catgcttaaa atgctacagc 100

 ggtgtgaaac agcagagcaa agaagcgccc ccagcttctg agagccctgg 150

 cccgagtccc ctcccccgtt agaaacaggg ctttgggatg gtcatggagc 200

 actgccagta actccaaccg cagcacgccg gcctgctcgc ccatcctccg 250

 gaagcggtct cgctcgccaa ccccgcagaa ccaggacgga gacaccatgg 300

 tggagaaggg ctcagatcac tcctcggaca agtccccgtc cacaccggag 350

 cagggcgtgc agcgcagctg ctcctcccag tccggccgga gcggcggcaa 400

 gaattccaag aaaagccaga gttggtataa tgtgttaagc cccacctaca 450

 agcagagaaa tgaagacttc agaaagctct ttaagcagct tccagacacg 500

 gagcgcctca ttgttgatta ctcatgtgca ctccaaagag acattctcct 550

 tcagggccga ctctacctct ctgaaaattg gatctgcttc tacagcaaca 600

 tcttccgctg ggaaactctg ctgacagtcc gtttgaaaga catctgttcc 650

 atgactaaag aaaaaacagc tcgcctcatt cccaatgcca tccaagtttg 700

 cactgattca gaaaagcact tcttcacttc gtttggggcc cgggatagga 750

 catatatgat gatgttccgg ctctggcaga atgctctcct tgaaaagcct 800

 ctgtgtccca aggagctctg gcactttgtt caccagtgct atgggaacga 850

 attgggcctg accagtgatg acgaggacta cgtgccccct gacgacgact 900

 tcaacacaat gggatactgt gaagagatcc ctgtggaaga gaatgaagtg 950

 aatgacagct catccaagag cagcatagag accaagccag atgccagtcc 1000

 acagctgccc aagaaatcca tcaccaacag cacactaaca tccacaggga 1050

 gcagtgaggc ccccgtctcg tttgatgggc tgcccctgga ggaagaggcg 1100

 ctggaaggag acgggtccct ggaaaaggag ctcgccattg acaacatcat 1150

 gggggagaag attgagatga tcgctcctgt gaactcccct tcactggact 1200

 tcaatgacaa tgaggacatc cccactgagc tcagtgactc ttccgacaca 1250

 cacgatgaag gagaggtcca ggccttctat gaggacctga gtggccggca 1300

 gtacgtgaat gaagtcttca acttcagcgt ggacaagctc tatgacctcc 1350

 tcttcaccaa ctcgcccttc cagcgggatt tcatggagca gcggcgcttc 1400

 tctgatatca tcttccatcc atggaaaaag gaggagaatg gaaaccagag 1450

 ccgagtgatt ctttacacca tcacccttac caaccctctg gctcccaaaa 1500

 ctgccactgt cagggagaca cagaccatgt acaaggcgag ccaggagagt 1550

 gaatgttacg tgatagatgc cgaagtcctc acccacgacg tgccctacca 1600

 cgactacttc tacacaatca atcgctacac gctcacccgt gtggctcgga 1650

 acaagagccg actcagggtc tccacagagc tgcgctatcg aaaacagccc 1700

 tgggggttag tgaaaacgtt catcgagaag aacttctgga gtgggctgga 1750

 ggactacttc cgccatttag agagcgagct ggccaaaacg gagagcactt 1800

 atttggctga gatgcacaga caatctccca aagagaaggc cagcaagact 1850

 acaacggtgc ggaggaggaa gcgtccccat gcccacctgc gagtccctca 1900

 cctggaagag gtgatgagcc cggtcaccac gcccacagat gaggatgtgg 1950

 gccacaggat caaacatgtg gcaggttcca cacagacgcg gcatatcccg 2000

 gaggacaccc ccaacggttt ccacctgcag agcgtgtcca agctgctgct 2050

 ggttatcagc tgtgtgatct gtttcagtct ggtgctgctg gtcatcctta 2100

 acatgatgct cttctacaaa ctctggatgt tggaatacac cacgcagacc 2150

 ctcactgcct ggcagggtct aaggctccaa gaaaggttac cccagtctca 2200

 gacagaatgg gcccagctct tagagtccca acaaaagtac cacgatactg 2250

 agctccaaaa atggagggaa atcatcaaat cctcagtgat gctccttgac 2300

 cagatgaagg actcgctcat caaccttcag aacggcatca ggtcccgcga 2350

 ctacacgtcg gaaagtgaag aaaagaggaa tcgctatcat tgacaaggca 2400

 ggaacagggt ggctgcaaga ggcctgtgca atacatgtac atagaccata 2450

 taaatatata tatataaata tatatatata cagaatataa atatatatat 2500

 tatatacaga ttttaaaaaa gagataatgc ctatgtacca gggagaagga 2550

 gcgggccctc ccgcgccctg tgctggccgg agcagcgttt tcttatggtg 2600

 gagcagctga ggagggcagg aaccgcctct cagcaccgac ctcccctgat 2650

 ctccctcctc ccaccctctg ttccccaccc cttcccttgc tggccattct 2700

 tggcttttag aagggaaatg ttgagccaaa gttatgcctg cgaagaccct 2750

 aaggtctcaa aaagaagtct taagacggca ttgcttaagg tgcttcattc 2800

 cctaatcccc ttttgatttg tttccaaaat aaaagagaat cttttcttcc 2850

 ctaccccagg cttccccagg cattctcttg ggaacacaga agcatcaagg 2900

 gagcccagtc taaactccta gggttggcca cccacttgat ccggaccgta 2950

 ctgagtgtca gatggagagg atgcttggaa agctaggaag gctgcattgt 3000

 gtggtggcag gctcccgaga ctcgtgttct gaaggatact ctcctccatc 3050

 acccctgcac cttcctccga cctgtgtagg gtgtggaccc agtaagggct 3100

 gggaatttct tactttccca cccgctttct ctctggtctt ctcccaggct 3150

 ggatctgggc gaagtgtcac tttttagtgc ctaaagtcct attgtttctc 3200

 tgtgccctaa gagcacattg tttattagcc agggtggagc gttttcgacc 3250

 ttattaaacc tcttttagtg cttctaagca agtcaggtct gtggctctga 3300

 ggccttcact tagagctgtc agtgtgattt ccaggatgag tcagggtgtg 3350

 ctgggccctc caggatttga gagagggaga gaaggccctt gccacgtccg 3400

 gggtgcaggg tctacccaca gaacactgtg agtggtgagc accaagatgg 3450

 gttgccagcc tcatttgctc tttgaacgaa ccaacattag ccagtggaga 3500

 cgactgtctg agacagtttg cacatagaaa aagcatctga gccactggag 3550

 ggaaggattt ggcaaaggtg catgtgtttg ggcaggaaaa ggccaagtga 3600

 aatctatgcc ctacgggagc cattcccaat cctgagtttc tcagacttgg 3650

 caatgggggt tctggcgggg gttggagtac aaatcctgct ctggtctctg 3700

 gccccacaga ggtgtaagat cattaagaag tagaaggcac tagcttcaaa 3750

 gagtgagaca ttcagggcct tttcagcatt ggcccactag caccatgcat 3800

 ttatctgaat tcacggggcc ctctgggcac attcatcatc cctcatacac 3850

 taactactgt ttcttcatgt aatgaccaaa agagtcccac cagctccagg 3900

 cagagctcgt ggagattcat gaaagagtca cagccagttt ggcatgcaga 3950

 ggtcttcagt cttgcttatt cttctcctgg gcttcttgac acaggggcag 4000

 aagaaacccc agatgtccca gatgtcccag aacatcagcc caaaagacag 4050

 aagattttat cactcatcta ccccaaagat aaagttgtat ttttctctta 4100

 gaatggcctt taattccctg tggcaattac agtttttgac ttttccatgt 4150

 gagaataagg ccttggtatt tccctaaggg caggatcaga aaacaggaag 4200

 gtccatgccc aggtgatcct ccaagggagg agggtgagga ggctccaggg 4250

 catgagctag agtggatatt cctcccctag aagaggagat gggaggaaat 4300

 gcagtttcat gtaatccctg tgaagagtgc ctatgcccac agcccagtgg 4350

 gtccttgttc agttcttgtc caggcctttg ggtgagggac actggtaggg 4400

 atcaaggctc atgggctctg agccaaagaa ggaggcatgg tgcagactgc 4450

 tggaaatctc ccacttggca cagccagaag ccaaaactat tcccagaaag 4500

 ttttgaatgc aaaacttgta gattcctgaa tttattccat acataattat 4550

 ttccttaagt tatttaatta ttaaaggtgc cacggtggga cctttgggat 4600

 gacttaaaaa gggttctttg ttgggagtca agtgacagag cagacctggc 4650

 cgcagggagt tgttctgctt ctgctttacc tctcaggacc attcccagga 4700

 ggaaaatgtg gcagagaggg cagtactgag tatgtcagaa gagccctcct 4750

 ggttttttag cgatttgaac ccactagaca atgtgtgcac atagggaatg 4800

 tcctttaaga atcatggatc tcttgtaggc tctctgtgtt ccaataattt 4850

 tttgactatc ataccaggaa aaaaccaaca actctattca ttcccaaaca 4900

 aaatctcttc ccccttagtc aatagcttgc gaaagagatc ttaactcacc 4950

 cttgcagata agtcttggag tgaaacaaat aaatagcatt gtattcctgg 5000

 ccatttgcct ggctagttgc tgtctacaag ggagcatcaa aacatcacta 5050

 cttcttatgt aacttcttcc agccagtgct tttattgttc gttttagttt 5100

 actggggaca cacaggagtc tttctgtaat gacttatgtg gtaaaatgtt 5150

 tgagagtttg cactcaattt taaagaattt gcagtttcta acaaggtgaa 5200

 gaacagctat aggatctaaa gttccattac agcttactgt gaaagaattg 5250

 acaagactgg cctcagacaa gctaatcatg gtgcgactct ctcccttcct 5300

 catccacctc tttggggaca agaggattac atctcaggcc agcaagatca 5350

 gctgcttgaa gctctgtgta agagcactgc actgacggtt tggagacctg 5400

 agcctgggtc ctgacttttc cattgactaa gctctgtggc cttgggcaag 5450

 tcactccccc tctctgagct tcagtatcct cctgtcacag gagggagttg 5500

 ggctagatca tctttaaggt aggttctagc tttgacatca tcttgggggt 5550

 taggccagag gctgggaaga ctgggtggac tttctcaatt gctctgccag 5600

 gagggaacaa gcccagaggc tgaagcttcc cagtatttag aggtgtggta 5650

 gggcagtgtc tgcattccca ggagacccag ggtgattaaa atttattctt 5700

 taggtggcta ggagggctgg ggaggcccag tggaagagag agagagagag 5750

 agagagagag agagagagag agagagatcg agagagatcg agcttgatgt 5800

 attgctcagt attcacttag aagggtttct ttctctttgg cctagtttgt 5850

 gaagggatct tcctttggac tttctctaag ttgggagaag aacattcttt 5900

 tcaatggagc tcatcttcta tctctagggt ctgttcagcc tttcatctat 5950

 ccatccttcc tctttattgg tagaagaaac agtggagagt agccacttct 6000

 ggttctagca cttctctttt gttaagatag ggtttggatt tagtatgaag 6050

 ctttggctaa aacccttggg tttgccttag aacactgaca ctaagaacct 6100

 ggaatgacat ggggaggaca aagagagctc aagaggaatg ctttgtgaga 6150

 agtggattct ctccgtgtcc ctgcccccca cccaaacttg aactatacct 6200

 tctgcataat gaattaacta gaaat 6225

<210> 5229
<211> 761
<212> PRT
<213> Homo sapien

<400> 5229
 Asn Ser Arg Ala Lys Lys Arg Pro Gln Leu Leu Arg Ala Leu Ala
   1               5                  10                  15

 Arg Val Pro Ser Pro Val Arg Asn Arg Ala Leu Gly Trp Ser Trp
                  20                  25                  30

 Ser Thr Ala Ser Asn Ser Asn Arg Ser Thr Pro Ala Cys Ser Pro
                  35                  40                  45

 Ile Leu Arg Lys Arg Ser Arg Ser Pro Thr Pro Gln Asn Gln Asp
                  50                  55                  60

 Gly Asp Thr Met Val Glu Lys Gly Ser Asp His Ser Ser Asp Lys
                  65                  70                  75

 Ser Pro Ser Thr Pro Glu Gln Gly Val Gln Arg Ser Cys Ser Ser
                  80                  85                  90

 Gln Ser Gly Arg Ser Gly Gly Lys Asn Ser Lys Lys Ser Gln Ser
                  95                 100                 105

 Trp Tyr Asn Val Leu Ser Pro Thr Tyr Lys Gln Arg Asn Glu Asp
                 110                 115                 120

 Phe Arg Lys Leu Phe Lys Gln Leu Pro Asp Thr Glu Arg Leu Ile
                 125                 130                 135

 Val Asp Tyr Ser Cys Ala Leu Gln Arg Asp Ile Leu Leu Gln Gly
                 140                 145                 150

 Arg Leu Tyr Leu Ser Glu Asn Trp Ile Cys Phe Tyr Ser Asn Ile
                 155                 160                 165

 Phe Arg Trp Glu Thr Leu Leu Thr Val Arg Leu Lys Asp Ile Cys
                 170                 175                 180

 Ser Met Thr Lys Glu Lys Thr Ala Arg Leu Ile Pro Asn Ala Ile
                 185                 190                 195

 Gln Val Cys Thr Asp Ser Glu Lys His Phe Phe Thr Ser Phe Gly
                 200                 205                 210

 Ala Arg Asp Arg Thr Tyr Met Met Met Phe Arg Leu Trp Gln Asn
                 215                 220                 225

 Ala Leu Leu Glu Lys Pro Leu Cys Pro Lys Glu Leu Trp His Phe
                 230                 235                 240

 Val His Gln Cys Tyr Gly Asn Glu Leu Gly Leu Thr Ser Asp Asp
                 245                 250                 255

 Glu Asp Tyr Val Pro Pro Asp Asp Asp Phe Asn Thr Met Gly Tyr
                 260                 265                 270

 Cys Glu Glu Ile Pro Val Glu Glu Asn Glu Val Asn Asp Ser Ser
                 275                 280                 285

 Ser Lys Ser Ser Ile Glu Thr Lys Pro Asp Ala Ser Pro Gln Leu
                 290                 295                 300

 Pro Lys Lys Ser Ile Thr Asn Ser Thr Leu Thr Ser Thr Gly Ser
                 305                 310                 315

 Ser Glu Ala Pro Val Ser Phe Asp Gly Leu Pro Leu Glu Glu Glu
                 320                 325                 330

 Ala Leu Glu Gly Asp Gly Ser Leu Glu Lys Glu Leu Ala Ile Asp
                 335                 340                 345

 Asn Ile Met Gly Glu Lys Ile Glu Met Ile Ala Pro Val Asn Ser
                 350                 355                 360

 Pro Ser Leu Asp Phe Asn Asp Asn Glu Asp Ile Pro Thr Glu Leu
                 365                 370                 375

 Ser Asp Ser Ser Asp Thr His Asp Glu Gly Glu Val Gln Ala Phe
                 380                 385                 390

 Tyr Glu Asp Leu Ser Gly Arg Gln Tyr Val Asn Glu Val Phe Asn
                 395                 400                 405

 Phe Ser Val Asp Lys Leu Tyr Asp Leu Leu Phe Thr Asn Ser Pro
                 410                 415                 420

 Phe Gln Arg Asp Phe Met Glu Gln Arg Arg Phe Ser Asp Ile Ile
                 425                 430                 435

 Phe His Pro Trp Lys Lys Glu Glu Asn Gly Asn Gln Ser Arg Val
                 440                 445                 450

 Ile Leu Tyr Thr Ile Thr Leu Thr Asn Pro Leu Ala Pro Lys Thr
                 455                 460                 465

 Ala Thr Val Arg Glu Thr Gln Thr Met Tyr Lys Ala Ser Gln Glu
                 470                 475                 480

 Ser Glu Cys Tyr Val Ile Asp Ala Glu Val Leu Thr His Asp Val
                 485                 490                 495

 Pro Tyr His Asp Tyr Phe Tyr Thr Ile Asn Arg Tyr Thr Leu Thr
                 500                 505                 510

 Arg Val Ala Arg Asn Lys Ser Arg Leu Arg Val Ser Thr Glu Leu
                 515                 520                 525

 Arg Tyr Arg Lys Gln Pro Trp Gly Leu Val Lys Thr Phe Ile Glu
                 530                 535                 540

 Lys Asn Phe Trp Ser Gly Leu Glu Asp Tyr Phe Arg His Leu Glu
                 545                 550                 555

 Ser Glu Leu Ala Lys Thr Glu Ser Thr Tyr Leu Ala Glu Met His
                 560                 565                 570

 Arg Gln Ser Pro Lys Glu Lys Ala Ser Lys Thr Thr Thr Val Arg
                 575                 580                 585

 Arg Arg Lys Arg Pro His Ala His Leu Arg Val Pro His Leu Glu
                 590                 595                 600

 Glu Val Met Ser Pro Val Thr Thr Pro Thr Asp Glu Asp Val Gly
                 605                 610                 615

 His Arg Ile Lys His Val Ala Gly Ser Thr Gln Thr Arg His Ile
                 620                 625                 630

 Pro Glu Asp Thr Pro Asn Gly Phe His Leu Gln Ser Val Ser Lys
                 635                 640                 645

 Leu Leu Leu Val Ile Ser Cys Val Ile Cys Phe Ser Leu Val Leu
                 650                 655                 660

 Leu Val Ile Leu Asn Met Met Leu Phe Tyr Lys Leu Trp Met Leu
                 665                 670                 675

 Glu Tyr Thr Thr Gln Thr Leu Thr Ala Trp Gln Gly Leu Arg Leu
                 680                 685                 690

 Gln Glu Arg Leu Pro Gln Ser Gln Thr Glu Trp Ala Gln Leu Leu
                 695                 700                 705

 Glu Ser Gln Gln Lys Tyr His Asp Thr Glu Leu Gln Lys Trp Arg
                 710                 715                 720

 Glu Ile Ile Lys Ser Ser Val Met Leu Leu Asp Gln Met Lys Asp
                 725                 730                 735

 Ser Leu Ile Asn Leu Gln Asn Gly Ile Arg Ser Arg Asp Tyr Thr
                 740                 745                 750

 Ser Glu Ser Glu Glu Lys Arg Asn Arg Tyr His
                 755                 760

<210> 5230
<211> 3120
<212> DNA
<213> Homo sapien

<400> 5230
 gtgagaccag gactgagaac agggagaggc gacccgaccc ccagggcccg 50

 gtgctcagga cagcacacag agccgctgaa aacgactgaa gagagcaagg 100

 gatttcctgg gacatctggc tctggagagt aaaaggccaa gctatgatag 150

 caactggtgg agtgataact ggcctggccg ccttgaaaag gcaagactct 200

 gccagatcac agcagcatgt caacctcagc ccgtctcctg ctacccaaga 250

 gaagaagccc atcaggcgcc ggccccgggc agatgttgtg gttgttcgtg 300

 gcaaaatccg gctttattcc ccatctggtt tttttcttat tttaggagtg 350

 ctcatctcca ttataggaat tgccatggcc gttcttggat attggcccca 400

 aaaagaacat tttattgatg ctgaaacaac actgtcaaca aatgaaactc 450

 aggtcattcg gaatgaaggc ggtgtggtgg ttcgcttctt tgagcagcat 500

 ttgcattctg ataagatgaa aatgcttggc ccgttcacca tggggattgg 550

 cattttcatt ttcatttgtg ctaatgccat tcttcatgaa aaccgtgaca 600

 aagagaccaa aatcatacac atgagggata tctattccac agtcattgac 650

 attcacacgc taagaatcaa ggagcaaagg caaatgaacg gcatgtacac 700

 tggtttgatg ggagaaacag aagtaaaaca gaatgggagc tcctgtgcct 750

 cgagattggc agcaaatacg atcgcctctt tctcgggttt tcggagcagt 800

 tttcgaatgg acagctccgt ggaggaggat gaacttatgt taaatgaagg 850

 taagagttct gggcatctta tgcccccttt gctctctgac agctctgtgt 900

 ctgtctttgg cctctatcca cctccttcca agacaactga tgataagacc 950

 agcggctcta agaaatgtga aaccaagtca attgtgtcat cgtccatcag 1000

 tgcttttaca ttgcctgtga tcaaacttaa taactgtgtt attgatgagc 1050

 ccagtataga taacatcact gaagatgctg acaacctcaa aagtaggtca 1100

 aggaatttgt caatggattc ccttgtggtt cctttgccca acaccagtga 1150

 atccttccag cccgtcagca cagtgctacc aaggaataat tccattgggg 1200

 agtcgttgtc gagtcagtac aagtcatcta tggctctcgg acctggggct 1250

 ggacagctct tgtctcctgg ggctgccaga agacagtttg ggtccaatac 1300

 atccttgcat ttgctctcgt cacactcaaa gtccttggac ttagaccggg 1350

 gtccctccac tctaactgtt caggcagaac aacggaaaca tccaagttgg 1400

 cctaggttgg atcggaacaa cagcaaggga tatatgaaac tagagaacaa 1450

 agaagacccg atggataggt tgcttgtgcc ccaagttgcc atcaaaaagg 1500

 actttaccaa taaggagaag cttcttatga tttcaagatc tcacaataat 1550

 ttgagttttg aacatgatga gtttttgagt aacaacctaa agaggggaac 1600

 ttctgaaaca aggttttaat gttaaaagaa tatatcattt tacaagggta 1650

 tatattttaa aacgattttc actggtgttt ccttcttaaa gtattggctg 1700

 taagcctttt taatcaaatg gtttgtagtg tattagaatt ggctgcttag 1750

 ttctgtaatg aagatggttg tatgtttggg ttacttgtga ctgcagtact 1800

 ctatgttacc acacatgatt ttatttttct cttcctttga aagcatgatc 1850

 tcttttatta atatgaatgc aaaatgcttg catccaaatt aaagcttatt 1900

 ttctttactt ttaagttctt tgattgccct attcataaaa tgaaatgtcc 1950

 agtatggaaa acatagggta ccaaagtgtg gaccaggagt acaaattcag 2000

 tcccaatact caatacgtat tatagatgac tatgagtgca aaccttagga 2050

 tgtgattttc tgaataattg ttctttgtag gatttggtta cattatttaa 2100

 aatgaaaaag atctagtttt agtgtgagct cagtaatgtt aattggttaa 2150

 gttcattgtg aatcttgagt tttagataag tagttatttt tttcaatatc 2200

 acttctgttt ttagtgatat tatatcaaga aacaacgtat tcaagagcca 2250

 tggctgacag tgccagatat acttagggat aaacatcaaa atgcaattat 2300

 agttgctata acgttagata ctcggaatca aaatttattt gcaagctgac 2350

 ttgataaact aaatgaacca ataaaatttg tagaaatgct atcctgaaat 2400

 aattatatac atgaagacaa tgttgactaa tgaattaaga tacattatat 2450

 actagttaat gctaactagt ctcagtacct gtttttagcc atctgttact 2500

 gtccaatagc acctcattcc cacattctat tttcccccgg tattctttag 2550

 atcctagtat ttggaaaaca atcggctaac cttgacattt ctttttacct 2600

 tcatatgcca ctatctcggt agttcaaaaa aatttaaatt cttgataaat 2650

 tgccttgaag tttaccttgt gctggagagc cttatgataa ctccaaagac 2700

 tttcttacgg tataatacat gttgtttagg attgtgtttc ttagtcactg 2750

 aagataataa atattaaaat ggatgttttc atcagaaaat tttcatgttt 2800

 tcctttaagg taacataatt gtaagaattg tttaataaaa tactcaggaa 2850

 attctaaagg tttctcctaa tacctaaaca tttctgaaca tcagtattgc 2900

 agttgtggaa gagcagaagg aggatacatt tgtttgtgtt gctccccaaa 2950

 attccacctt gcatttgcat cacaaacttc cctcaattga ggcagttttc 3000

 tttgttagaa cattaagtct gtgtattgta atagagtggg ctcaatattt 3050

 tactataaag catttaataa actgttatta atagaaaaaa aaaaaaaaaa 3100

 aaaaaaaaaa aaaaaaaaaa 3120

<210> 5231
<211> 491
<212> PRT
<213> Homo sapien

<400> 5231
 Met Ile Ala Thr Gly Gly Val Ile Thr Gly Leu Ala Ala Leu Lys
   1               5                  10                  15

 Arg Gln Asp Ser Ala Arg Ser Gln Gln His Val Asn Leu Ser Pro
                  20                  25                  30

 Ser Pro Ala Thr Gln Glu Lys Lys Pro Ile Arg Arg Arg Pro Arg
                  35                  40                  45

 Ala Asp Val Val Val Val Arg Gly Lys Ile Arg Leu Tyr Ser Pro
                  50                  55                  60

 Ser Gly Phe Phe Leu Ile Leu Gly Val Leu Ile Ser Ile Ile Gly
                  65                  70                  75

 Ile Ala Met Ala Val Leu Gly Tyr Trp Pro Gln Lys Glu His Phe
                  80                  85                  90

 Ile Asp Ala Glu Thr Thr Leu Ser Thr Asn Glu Thr Gln Val Ile
                  95                 100                 105

 Arg Asn Glu Gly Gly Val Val Val Arg Phe Phe Glu Gln His Leu
                 110                 115                 120

 His Ser Asp Lys Met Lys Met Leu Gly Pro Phe Thr Met Gly Ile
                 125                 130                 135

 Gly Ile Phe Ile Phe Ile Cys Ala Asn Ala Ile Leu His Glu Asn
                 140                 145                 150

 Arg Asp Lys Glu Thr Lys Ile Ile His Met Arg Asp Ile Tyr Ser
                 155                 160                 165

 Thr Val Ile Asp Ile His Thr Leu Arg Ile Lys Glu Gln Arg Gln
                 170                 175                 180

 Met Asn Gly Met Tyr Thr Gly Leu Met Gly Glu Thr Glu Val Lys
                 185                 190                 195

 Gln Asn Gly Ser Ser Cys Ala Ser Arg Leu Ala Ala Asn Thr Ile
                 200                 205                 210

 Ala Ser Phe Ser Gly Phe Arg Ser Ser Phe Arg Met Asp Ser Ser
                 215                 220                 225

 Val Glu Glu Asp Glu Leu Met Leu Asn Glu Gly Lys Ser Ser Gly
                 230                 235                 240

 His Leu Met Pro Pro Leu Leu Ser Asp Ser Ser Val Ser Val Phe
                 245                 250                 255

 Gly Leu Tyr Pro Pro Pro Ser Lys Thr Thr Asp Asp Lys Thr Ser
                 260                 265                 270

 Gly Ser Lys Lys Cys Glu Thr Lys Ser Ile Val Ser Ser Ser Ile
                 275                 280                 285

 Ser Ala Phe Thr Leu Pro Val Ile Lys Leu Asn Asn Cys Val Ile
                 290                 295                 300

 Asp Glu Pro Ser Ile Asp Asn Ile Thr Glu Asp Ala Asp Asn Leu
                 305                 310                 315

 Lys Ser Arg Ser Arg Asn Leu Ser Met Asp Ser Leu Val Val Pro
                 320                 325                 330

 Leu Pro Asn Thr Ser Glu Ser Phe Gln Pro Val Ser Thr Val Leu
                 335                 340                 345

 Pro Arg Asn Asn Ser Ile Gly Glu Ser Leu Ser Ser Gln Tyr Lys
                 350                 355                 360

 Ser Ser Met Ala Leu Gly Pro Gly Ala Gly Gln Leu Leu Ser Pro
                 365                 370                 375

 Gly Ala Ala Arg Arg Gln Phe Gly Ser Asn Thr Ser Leu His Leu
                 380                 385                 390

 Leu Ser Ser His Ser Lys Ser Leu Asp Leu Asp Arg Gly Pro Ser
                 395                 400                 405

 Thr Leu Thr Val Gln Ala Glu Gln Arg Lys His Pro Ser Trp Pro
                 410                 415                 420

 Arg Leu Asp Arg Asn Asn Ser Lys Gly Tyr Met Lys Leu Glu Asn
                 425                 430                 435

 Lys Glu Asp Pro Met Asp Arg Leu Leu Val Pro Gln Val Ala Ile
                 440                 445                 450

 Lys Lys Asp Phe Thr Asn Lys Glu Lys Leu Leu Met Ile Ser Arg
                 455                 460                 465

 Ser His Asn Asn Leu Ser Phe Glu His Asp Glu Phe Leu Ser Asn
                 470                 475                 480

 Asn Leu Lys Arg Gly Thr Ser Glu Thr Arg Phe
                 485                 490

<210> 5232
<211> 2065
<212> DNA
<213> Homo sapien

<400> 5232
 gggacgcgag cgggatccaa acttccggtg cctgcagagc tcggagcggc 50

 ggaggcagag accgaggctg caccggcaga ggctgcgggg cggacgcgcg 100

 ggccggcgca gccatggtga agattagctt ccagcccgcc gtggctggca 150

 tcaagggcga caaggctgac aaggcgtcgg cgtcggcccc tgcgccggcc 200

 tcggccaccg agatcctgct gacgccggct agggaggagc agcccccaca 250

 acatcgatcc aagagggggg gctcagtggg cggcgtgtgc tacctgtcga 300

 tgggcatggt cgtgctgctc atgggcctcg tgttcgcctc tgtctacatc 350

 tacagatact tcttccttgc gcagctggcc cgagataact tcttccgctg 400

 tggtgtgctg tatgaggact ccctgtcctc ccaggtccgg actcagatgg 450

 agctggaaga ggatgtgaaa atctacctcg acgagaacta cgagcgcatc 500

 aacgtgcctg tgccccagtt tggcggcggt gaccctgcag acatcatcca 550

 tgacttccag cggggtctga ctgcgtacca tgatatctcc ctggacaagt 600

 gctatgtcat cgaactcaac accaccattg tgctgccccc tcgcaacttc 650

 tgggagctcc tcatgaacgt gaagaggggg acctacctgc cgcagacgta 700

 catcatccag gaggagatgg tggtcacgga gcatgtcagt gacaaggagg 750

 ccctggggtc cttcatctac cacctgtgca acgggaaaga cacctaccgg 800

 ctccggcgcc gggcaacgcg gaggcggatc aacaagcgtg gggccaagaa 850

 ctgcaatgcc atccgccact tcgagaacac cttcgtggtg gagacgctca 900

 tctgcggggt ggtgtgaggc cctcctcccc cagaaccccc tgccgtgttc 950

 ctcttttctt ctttccggct gctctctggc cctcctcctt ccccctgctt 1000

 agcttgtact ttggacgcgt ttctatagag gtgacatgtc tctccattcc 1050

 tctccaaccc tgcccacctc cctgtaccag agctgtgatc tctcggtggg 1100

 gggcccatct ctgctgacct gggtgtggcg gagggagagg cgatgctgca 1150

 aagtgttttc tgtgtcccac tgtcttgaag ctgggcctgc caaagcctgg 1200

 gcccacagct gcaccggcag cccaagggga aggaccggtt gggggagccg 1250

 ggcatgtgag gccctgggca aggggatggg gctgtggggg cggggcggca 1300

 tgggcttcag aagtatctgc acaattagaa aagtcctcag aagctttttc 1350

 ttggagggta cactttcttc actgtcccta ttcctagacc tggggcttga 1400

 gctgaggatg ggacgatgtg cccagggagg gacccaccag agcacaagag 1450

 aaggtggcta cctgggggtg tcccagggac tctgtcagtg ccttcagccc 1500

 accagcagga gcttggagtt tggggagtgg ggatgagtcc gtcaagcaca 1550

 actgttctct gagtggaacc aaagaagcaa ggagctagga cccccagtcc 1600

 tgccccccag gagcacaagc agggtcccct cagtcaaggc agtgggatgg 1650

 gcggctgagg aacggggcag gcaaggtcac tgctcagtca cgtccacggg 1700

 ggacgagccg tgggttctgc tgagtaggtg gagctcattg ctttctccaa 1750

 gcttggaact gttttgaaag ataacacaga gggaaaggga gagccacctg 1800

 gtacttgtcc accctgcctc ctctgttctg aaattccatc cccctcagct 1850

 taggggaatg cacctttttc cctttccttc tcacttttgc atgtttttac 1900

 tgatcattcg atatgctaac cgttctcagc cctgagcctt ggagaggagg 1950

 gctgtaacgc cttcagtcag tctctgggga tgaaactctt aaatgctttg 2000

 tatattttct caattagatc tcttttcaga agtgtctata gaacaataaa 2050

 aatcttttac ttctg 2065

<210> 5233
<211> 267
<212> PRT
<213> Homo sapien

<400> 5233
 Met Val Lys Ile Ser Phe Gln Pro Ala Val Ala Gly Ile Lys Gly
   1               5                  10                  15

 Asp Lys Ala Asp Lys Ala Ser Ala Ser Ala Pro Ala Pro Ala Ser
                  20                  25                  30

 Ala Thr Glu Ile Leu Leu Thr Pro Ala Arg Glu Glu Gln Pro Pro
                  35                  40                  45

 Gln His Arg Ser Lys Arg Gly Gly Ser Val Gly Gly Val Cys Tyr
                  50                  55                  60

 Leu Ser Met Gly Met Val Val Leu Leu Met Gly Leu Val Phe Ala
                  65                  70                  75

 Ser Val Tyr Ile Tyr Arg Tyr Phe Phe Leu Ala Gln Leu Ala Arg
                  80                  85                  90

 Asp Asn Phe Phe Arg Cys Gly Val Leu Tyr Glu Asp Ser Leu Ser
                  95                 100                 105

 Ser Gln Val Arg Thr Gln Met Glu Leu Glu Glu Asp Val Lys Ile
                 110                 115                 120

 Tyr Leu Asp Glu Asn Tyr Glu Arg Ile Asn Val Pro Val Pro Gln
                 125                 130                 135

 Phe Gly Gly Gly Asp Pro Ala Asp Ile Ile His Asp Phe Gln Arg
                 140                 145                 150

 Gly Leu Thr Ala Tyr His Asp Ile Ser Leu Asp Lys Cys Tyr Val
                 155                 160                 165

 Ile Glu Leu Asn Thr Thr Ile Val Leu Pro Pro Arg Asn Phe Trp
                 170                 175                 180

 Glu Leu Leu Met Asn Val Lys Arg Gly Thr Tyr Leu Pro Gln Thr
                 185                 190                 195

 Tyr Ile Ile Gln Glu Glu Met Val Val Thr Glu His Val Ser Asp
                 200                 205                 210

 Lys Glu Ala Leu Gly Ser Phe Ile Tyr His Leu Cys Asn Gly Lys
                 215                 220                 225

 Asp Thr Tyr Arg Leu Arg Arg Arg Ala Thr Arg Arg Arg Ile Asn
                 230                 235                 240

 Lys Arg Gly Ala Lys Asn Cys Asn Ala Ile Arg His Phe Glu Asn
                 245                 250                 255

 Thr Phe Val Val Glu Thr Leu Ile Cys Gly Val Val
                 260                 265

<210> 5234
<211> 4573
<212> DNA
<213> Homo sapien

<400> 5234
 cgcgtgtcta cgcggacgca ccggctaagc tgcttctgcc gccgccggcc 50

 gcctgggacc ttgcggtgag gctgcgcggg gccgaggccg cctccgagcg 100

 ccaggtttat tcagtcacca tgaagctgct gctgctgcac ccggccttcc 150

 agagctgcct cctgctgacc ctgcttggct tatggagaac cacccctgag 200

 gctcacgctt catccctggg tgcaccagct atcagcgctg cctccttcct 250

 gcaggatcta atacatcggt atggcgaggg tgacagcctc actctgcagc 300

 agctgaaggc cctgctcaac cacctggatg tgggagtggg ccggggtaat 350

 gtcacccagc acgtgcaagg acacaggaac ctctccacgt gctttagttc 400

 tggagacctc ttcactgccc acaatttcag cgagcagtcg cggattggga 450

 gcagcgagct ccaggagttc tgccccacca tcctccagca gctggattcc 500

 cgggcctgca cctcggagaa ccaggaaaac gaggagaatg agcagacgga 550

 ggaggggcgg ccaagcgctg ttgaagtgtg gggatacggt ctcctctgtg 600

 tgaccgtcat ctccctctgc tccctcctgg gggccagcgt ggtgcccttc 650

 atgaagaaga ccttttacaa gaggctgctg ctctacttca tagctctggc 700

 gattggaacc ctctactcca acgccctctt ccagctcatc ccggaggcat 750

 ttggtttcaa ccctctggaa gattattatg tctccaagtc tgcagtggtg 800

 tttgggggct tttatctttt ctttttcaca gagaagatct tgaagattct 850

 tcttaagcag aaaaatgagc atcatcatgg acacagccat tatgcctctg 900

 agtcgcttcc ctccaagaag gaccaggagg agggggtgat ggagaagctg 950

 cagaacgggg acctggacca catgattcct cagcactgca gcagtgagct 1000

 ggacggcaag gcgcccatgg tggacgagaa ggtcattgtg ggctcgctct 1050

 ctgtgcagga cctgcaggct tcccagagtg cttgctactg gctgaaaggt 1100

 gtccgctact ctgatatcgg cactctggcc tggatgatca ctctgagcga 1150

 cggcctccac aatttcatcg atggcctggc catcggtgct tccttcactg 1200

 tgtcagtttt ccaaggcatc agcacctcgg tggccatcct ctgtgaggag 1250

 ttcccacatg agctaggaga ctttgtcatc ctgctcaacg ctgggatgag 1300

 catccaacaa gctctcttct tcaacttcct ttctgcctgc tgctgctacc 1350

 tgggtctggc ctttggcatc ctggccggca gccacttctc tgccaactgg 1400

 atttttgcgc tagctggagg aatgttcttg tatatttctc tggctgatat 1450

 gttccctgag atgaatgagg tctgtcaaga ggatgaaagg aagggcagca 1500

 tcttgattcc atttatcatc cagaacctgg gcctcctgac tggattcacc 1550

 atcatggtgg tcctcaccat gtattcagga cagatccaga ttgggtaggg 1600

 ctctgccaag agcctgtggg actggaagtc gggccctggg ctgcccgatc 1650

 gccagcccga ggacttacca tccacaatgc accacggaag aggccgttct 1700

 atgaaaaact gacacagact gtattcctgc attcaaatgt cagccgtttg 1750

 taaaatgctg tatcctagga ataagctgcc ctggtaacca gtctctagct 1800

 agtgcctctt gccctctcct cacctccttt tctctcagtg actctggaac 1850

 ctgaatgcag cttacaagac aagcctgact tttttctctg attaccttgg 1900

 cctcctcttg gaaccagtgc tgaaaggttt tgaatccttt acccaacaat 1950

 gcaaaaatag agccaatggt tataacttgg ctagaaatat caagagttga 2000

 atccatagtg tggggcccat gactctagct gggcaccttg gacctccagc 2050

 tggccaatag aagagacagg agacaggaag ccttcccatt ttttcaaagt 2100

 ctgtttaatt gcctattact tctctcaaag agaacctgaa gtcagaacac 2150

 atgagcaggg tgagaggtga ggcaaggttc atcctgaatg ggagaggaag 2200

 tcgaaccact gctgtgtgtc ttgtcaggat gctcacttgt tcctactgag 2250

 atgctggata ttgattttgt aacagcacct ggtgtttcac ggctgtccga 2300

 gtgagctaac gtggcggtgt ggctgcctgg acctcctctt tcaggttaac 2350

 gctgacagaa tggaggctca ggctgtctgc aagaaaacag ttggtttggc 2400

 tgtgattttg acctcctctt ccccactgcc atcttctaag agactttgta 2450

 gctgcctcct agaagcacat tctgagcaca tttgagacct ctgtgttaga 2500

 ggggagactg cacaaactat cctcccccag gttgagacgt ctgcagagtg 2550

 gcaagctgac ttgtagaaat ggggtgccat ttatgctcta cttagacaag 2600

 ggtaatcaga aatggaatca gtgcaggcaa aatttaggat ttgccgcttc 2650

 cataaatcaa agcatgacta atagggggtc tctgaaatgt aagggcacaa 2700

 acttcactta gggcatcgca gatgtttgca gaatggttgg cctaatgatt 2750

 atgctacaga tgggttttaa atgacccgtc taggttactg cttccttgca 2800

 aaaaaagtcg aatcctgcat tgaattgaat atgaatttct ctaactctct 2850

 ccagaaaatg gatggagata acttgtcttt aaaactgtag gccagcctta 2900

 gccactgtgg agcccttgcc tccgagctct ggcttcaagg ggagctcttc 2950

 tccaggttca ctaggtgaat tgatttatta ttatcatatt gataatgtga 3000

 gattctttag ccactttggg gagcctgtct ctccagaagc ctttcttagt 3050

 ggtgcccaca gttggagccc aggggccatg tttgcaaact gattcatgtg 3100

 catggctgac aggagtactg gttcactacc aatgcctgag cttttctctt 3150

 acatagaaaa actgtccact ctcagtaatc acaagcagca tccgttttgt 3200

 tttctcttct tgggagacat ctgtcaaacc aggaatattc ttgaaaagaa 3250

 cgtgagcagg aaaaactgct ggtgatactt tttttaagtt ttgtttttat 3300

 cttgcctgtt ggcttcaata catttgagaa tacgctgaag agggaaaatt 3350

 tcagtgatgg agattctaga ttaaatatca ggactgattt cctggtggga 3400

 ttatggtcca gttttaccaa agaaccaatt ccttgaatgt tggaatctaa 3450

 ctttttatat tgtcattatt attgttgttt ttaaacggtt ctttgtcttt 3500

 tctgttttat ttttctcaag ctgctttcag gagctagcag aaaataactc 3550

 aaagttgaag actctggaag attttgcttt aacctaactc gcattgatgt 3600

 attaaattta taattttagc attcccaata gatcctatca ttccttaaac 3650

 ataataccct ttgtcttgga gtagaatact aagttagagt tagtggattt 3700

 ctagtttagg agaggagctc aaaactataa tctttaacaa attgaaaaat 3750

 gaaatagggt gttttccctt tttgtgcaca cctatattac cttaagaaat 3800

 ttccttccat agacagctgc ctcaaaggga aatcctcttt aaaccgtagt 3850

 tggcgcagag gtcagtccta gtcggagctt aggaggggcg gagacgctca 3900

 catcgtctga cttgagtcgc cactgattgt ggcaacagct ttgcctcatg 3950

 agtcaaaaat tggcaatttc ttttgatttt tagttgttga atttgctgtt 4000

 tcaagcattt gtacatatta gaagtctaag gagtagcaag tcagtgggag 4050

 gactttttca cccctggcat tagcagcttc gacctcattt tccagatgca 4100

 ccagctccta ttaataagtt agcaaggaaa gtgtatgtca cgtgcaggaa 4150

 cagtgaggca gggacagggg ttctgctcct tctcacttca ccaccggcac 4200

 acagcttgcc cctgtctttg cccccaaagg tattttgtgt ctagtgtcaa 4250

 attggagcta ttcttcactg gtccttaacc ttgggtttta aaaagaaggc 4300

 ttctctgttt gggtagcgta agagctgagt atagtaagtc ctcttccaaa 4350

 gagatggcaa tatgctgggc atctacttta aaacaaagtt gtctgatttt 4400

 tgcaagagag gttaggattt tattgttctt atttcccttt acagttctgc 4450

 agttccatca cagtattttt ttaaataact caggtgtatg agcagaaatt 4500

 agaaaagaaa attaacttat gtggactgta aatgttttat ttgtaagatt 4550

 ctataaataa agctatattc tgt 4573

<210> 5235
<211> 2728
<212> DNA
<213> Homo sapien

<400> 5235
 accgcggaaa gcatgttgtg gctgttccaa tcgctcctgt ttgtcttctg 50

 ctttggccca gggaatgtag tttcacaaag cagcttaacc ccattgatgg 100

 tgaacgggat tctgggggag tcagtaactc ttcccctgga gtttcctgca 150

 ggagagaagg tcaacttcat cacttggctt ttcaatgaaa catctcttgc 200

 cttcatagta ccccatgaaa ccaaaagtcc agaaatccac gtgactaatc 250

 cgaaacaggg aaagcgactg aacttcaccc agtcctactc cctgcaactc 300

 agcaacctga agatggaaga cacaggctct tacagagccc agatatccac 350

 aaagacctct gcaaagctgt ccagttacac tctgaggata ttaagacaac 400

 tgaggaacat acaagttacc aatcacagtc agctatttca gaatatgacc 450

 tgtgagctcc atctgacttg ctctgtggag gatgcagatg acaatgtctc 500

 attcagatgg gaggccttgg gaaacacact ttcaagtcag ccaaacctca 550

 ctgtctcctg ggaccccagg atttccagtg aacaggacta cacctgcata 600

 gcagagaatg ctgtcagtaa tttatccttc tctgtctctg cccagaagct 650

 ttgcgaagat gttaaaattc aatatacaga taccaaaatg attctgttta 700

 tggtttctgg gatatgcata gtcttcggtt tcatcatact gctgttactt 750

 gttttgagga aaagaagaga ttccctatct ttgtctactc agcgaacaca 800

 gggccccgag tccgcaagga acctagagta tgtttcagtg tctccaacga 850

 acaacactgt gtatgcttca gtcactcatt caaacaggga aacagaaatc 900

 tggacaccta gagaaaatga tactatcaca atttactcca caattaatca 950

 ttccaaagag agtaaaccca ctttttccag ggcaactgcc cttgacaatg 1000

 tcgtgtaagt tgctgaaagg cctcagagga attcgggaat gacacgtctt 1050

 ctgatcccat gagacagaac aaagaacagg aagcttggtt cctgttgttc 1100

 ctggcaacag aatttgaata tctaggatag gatgatcacc tccagtcctt 1150

 cggacttaaa cctgcctacc tgagtcaaac acctaaggat aacatcattt 1200

 ccagcatgtg gttcaaataa tattttccaa tccacttcag gccaaaacat 1250

 gctaaagata acacaccagc acattgactc tctctttgat aactaagcaa 1300

 atggaattat ggttgacaga gagtttatga tccagaagac aaccacttct 1350

 ctccttttag aaagcagcag gattgactta ttgagaaata atgcagtgtg 1400

 ttggttacat gtgtagtctc tggagttgga tgggcccatc ctgatacaag 1450

 ttgagcatcc cttgtctgaa atgcttggga ttagaaatgt ttcagatttc 1500

 aatttttttt cagattttgg aatatttgca ttatatttag cggttgagta 1550

 tccaaatcca aaaatccaaa attcaaaatg ctccaataag catttccctt 1600

 gagtttcatt gatgtcgatg cagtgctcaa aatctcagat tttggagcat 1650

 tttggatatt ggatttttgg atttgggatg ctcaacttgt acaatgttta 1700

 ttagacacat ctcctgggac atactgccta accttttgga gccttagtct 1750

 cccagactga aaaaggaaga ggatggtatt acatcagctc cattgtttga 1800

 gccaagaatc taagtcatcc ctgactccag tgtctttgtc accaggccct 1850

 ttggactcta cctcagaaat atttcttgga ccttccactt ctcctccaac 1900

 tccttgacca ccatcctgta tccaaccatc accacctcta acctgaatcc 1950

 taccttaaga tcagaacagt tgtcctcact tttgttcttg tccctctcca 2000

 acccactctc cacaagatgg ccagagtaat gtttttaata taaattggat 2050

 ccttcagttt cctgcttaaa accctgcagg tttcccaatg cactcagaaa 2100

 gaaatccagt ttccatggcc ctggatggtc tggcccacct ccagcctcag 2150

 ctagcattac ccttctgaca ctctctatgt agcctccctg atcttctttc 2200

 agctcctcta ttaaaggaaa agttctttat gttaattatt tacatcttcc 2250

 tgcaggccct tcctctgcct gctggggtcc tcctattctt taggtttaat 2300

 tttaaatatg tcacctccta agagaaacct tcccagacca ctctttctaa 2350

 aatgaatctt ctaggctggg catggtggct cacacctgta atcccagtac 2400

 tttgggaggc caagggggga gatcacttga ggtcaggagt tcaagaccag 2450

 cctggccaac ttggtgaaac cccgtcttta ctaaaaatac aaaaaaatta 2500

 gccaggcgtg gtggtgcacc cctaaaatcc cagctacttg agagactgag 2550

 gcaggagaat cgcttgaacc caggaggtgg aggttccagt gagccaaaat 2600

 catgccaatg tattccagtc tgggtgacag agtgagactc tgtctcaaaa 2650

 aataaataaa taaaataaaa tgaaatagat cttataaaaa aaaaaaaaaa 2700

 aaaaaaaaaa aaaaaaaaaa aaaaaaaa 2728

<210> 5236
<211> 331
<212> PRT
<213> Homo sapien

<400> 5236
 Met Leu Trp Leu Phe Gln Ser Leu Leu Phe Val Phe Cys Phe Gly
   1               5                  10                  15

 Pro Gly Asn Val Val Ser Gln Ser Ser Leu Thr Pro Leu Met Val
                  20                  25                  30

 Asn Gly Ile Leu Gly Glu Ser Val Thr Leu Pro Leu Glu Phe Pro
                  35                  40                  45

 Ala Gly Glu Lys Val Asn Phe Ile Thr Trp Leu Phe Asn Glu Thr
                  50                  55                  60

 Ser Leu Ala Phe Ile Val Pro His Glu Thr Lys Ser Pro Glu Ile
                  65                  70                  75

 His Val Thr Asn Pro Lys Gln Gly Lys Arg Leu Asn Phe Thr Gln
                  80                  85                  90

 Ser Tyr Ser Leu Gln Leu Ser Asn Leu Lys Met Glu Asp Thr Gly
                  95                 100                 105

 Ser Tyr Arg Ala Gln Ile Ser Thr Lys Thr Ser Ala Lys Leu Ser
                 110                 115                 120

 Ser Tyr Thr Leu Arg Ile Leu Arg Gln Leu Arg Asn Ile Gln Val
                 125                 130                 135

 Thr Asn His Ser Gln Leu Phe Gln Asn Met Thr Cys Glu Leu His
                 140                 145                 150

 Leu Thr Cys Ser Val Glu Asp Ala Asp Asp Asn Val Ser Phe Arg
                 155                 160                 165

 Trp Glu Ala Leu Gly Asn Thr Leu Ser Ser Gln Pro Asn Leu Thr
                 170                 175                 180

 Val Ser Trp Asp Pro Arg Ile Ser Ser Glu Gln Asp Tyr Thr Cys
                 185                 190                 195

 Ile Ala Glu Asn Ala Val Ser Asn Leu Ser Phe Ser Val Ser Ala
                 200                 205                 210

 Gln Lys Leu Cys Glu Asp Val Lys Ile Gln Tyr Thr Asp Thr Lys
                 215                 220                 225

 Met Ile Leu Phe Met Val Ser Gly Ile Cys Ile Val Phe Gly Phe
                 230                 235                 240

 Ile Ile Leu Leu Leu Leu Val Leu Arg Lys Arg Arg Asp Ser Leu
                 245                 250                 255

 Ser Leu Ser Thr Gln Arg Thr Gln Gly Pro Glu Ser Ala Arg Asn
                 260                 265                 270

 Leu Glu Tyr Val Ser Val Ser Pro Thr Asn Asn Thr Val Tyr Ala
                 275                 280                 285

 Ser Val Thr His Ser Asn Arg Glu Thr Glu Ile Trp Thr Pro Arg
                 290                 295                 300

 Glu Asn Asp Thr Ile Thr Ile Tyr Ser Thr Ile Asn His Ser Lys
                 305                 310                 315

 Glu Ser Lys Pro Thr Phe Ser Arg Ala Thr Ala Leu Asp Asn Val
                 320                 325                 330

 Val


<210> 5237
<211> 3108
<212> DNA
<213> Homo sapien

<400> 5237
 ggagcccatg atttcctgga agagccctag agctttgctt tttctctcct 50

 gcagcactta accgaaacca gttttgcaat caattcctgt tcaaaggcca 100

 ccctactctt cctatccgtc tttctccagc ccagacactc acagccccct 150

 gccagaccag gggacctcgg agaggcaagg acagaggttc aggatcttcc 200

 tctccctcgg gacccaaggc cacaaaggag agctccgtgg agagaagaaa 250

 atcatttgac tcctggggac acagatttgc tgccacagag gctgatggac 300

 aaccaggcgg agagagaaag tgaggctggt gttggtttgc aaagggatga 350

 ggatgacgct cctctgtgtg aagacgtgga gctacaagac ggagatctgt 400

 cccccgaaga aaaaatattt ttgagagaat ttcccagatt gaaagaagat 450

 ctgaaaggga acattgacaa gctccgtgcc ctcgcagacg atattgacaa 500

 aacccacaag aaattcacca aggctaacat ggtggccacc tctactgctg 550

 tcatctctgg agtgatgagc ctcctgggtt tagcccttgc cccagcaaca 600

 ggaggaggaa gcctgctgct ctccaccgct ggtcaaggtt tggcaacagc 650

 agctggggtc accagcatcg tgagtggtac gttggaacgc tccaaaaata 700

 aagaagccca agcacgggcg gaagacatac tgcccaccta cgaccaagag 750

 gacagggagg atgaggaaga gaaggcagac tatgtcacag ctgctggaaa 800

 gattatctat aatcttagaa acaccttgaa gtatgccaag aaaaacgtcc 850

 gtgcattttg gaaactcaga gccaacccac gcttggccaa tgctaccaag 900

 cgtcttctga ccactggcca agtctcctcc cggagccgcg tgcaggtgca 950

 aaaggccttt gcgggaacaa cactggcgat gaccaaaaat gctcgcgtgc 1000

 tgggaggtgt gatgtccgcc ttctcccttg gctatgactt ggccactctc 1050

 tcaaaggaat ggaagcacct gaaggaagga gcaaggacaa agtttgcgga 1100

 agagttgaga gccaaggcct tggagctgga gaggaaactc acagaactca 1150

 cccagctcta caagagcttg cagcagaaag tgaggtcaag ggccagaggg 1200

 gtggggaagg atttaactgg gacctgcgaa accgaggctt actggaagga 1250

 gttaagggag catgtgtgga tgtggctgtg gctgtgtgtg tgtctgtgtg 1300

 tctgtgtgta tgtacagttt acatgaatgt tcctcaggac atggcataca 1350

 atggccttgg aggtccaaat aatatcaagt acatcttgga gatgagggtg 1400

 cctgtcctgg acagacctcg gcatgccttc tgtttctcct tcaatgctcc 1450

 ttaaggccta tgtgctggga aaagggtctt ccctgtttgt ttgtttgttt 1500

 gtttgtttgt ttgttttgag actccagtct gggtgtcaga atgagacccc 1550

 atctcaaaaa aaaaaaaaaa aaaaaaaaag aagaagaata cagtcatgta 1600

 tctcttggtg acagggacgc attctgataa atgtgtcatt aggcaattgc 1650

 attgtagtgt gattatcaca gattgtactt atacaaaact tagatggcat 1700

 agcctactgc atacctaggc tatatgggag agcctattgc tcccaggcta 1750

 cgcacctgta cagcatgtga ctactgaata ctataggcaa ttgcagcaca 1800

 atgggaaata tttgtgtatc taaacatatg taaacagaga aaaaggaaag 1850

 taaaaatatg gcataaaaga taagaattgg ctctcctgta cagggcactt 1900

 actacgaatg gagcttgcag ggctgagagt tgctccagat gagtcagtga 1950

 gtggtgaatg aatgtgaagg cctagggcat tactgtatac tactgtaggc 2000

 tttataaaca cagcacactt agggtacaca aaatgcatat taaaacattt 2050

 tcttccttca gtatattagg caataggaat ttttcaagtc cactataaat 2100

 cttatcaaac catggttgta tatgcagttg accgaaacat tgttattgga 2150

 cacataacta tagttgaaag aataagcaaa aagtctatct aggtgtgctg 2200

 tcttgagcaa cttttaatta ttctcctgtc ctgcaatatg agttaatctt 2250

 ctctgatcga tgtagattcc aggaaggggt gtccaggaca attaccttcc 2300

 ttctggagaa acttccctta atcaaataag agaacttcaa agaaaatccc 2350

 tccctgtgct ttggaaggga agggaggtgg gcagcagtgg gtcagagata 2400

 gacctttgtt ctcttatttc tgaggccctt cagtctcctt tattcaaagc 2450

 actcagcatg ccaaagcacc ctattttagg gtatcttttt ctgagcccta 2500

 aacactgtgt tggggatgtc aactgtgaca ggaaaatatc ttggggcccc 2550

 agaatcacta aggaaaactc aagcttaggg aaacttctta gggcaaaccc 2600

 acctcccact ctattcaaag ttatctctct gctcactgag atagatacat 2650

 atctgattgc ctcctttgga aaggctaatc agaaactcaa aagaatgcaa 2700

 ctgtttgtgt ctcacctatc tgtgacctgg aagctccctc cccactgaac 2750

 caatgttctt cttacatata ttgattaatg tcttatgtct ccctaaaatg 2800

 tataaaacca aggtatgccc caaccatctt ggccacatgt catcaggact 2850

 tcctgagtct gtgtcacagt gtgtcctcaa ccttggcaaa ataaactttc 2900

 taaattaact gagacctgtc tcggattttc tgggttcaca ttttggaaac 2950

 catgaatgga ttctgggtgg agatgcccct gacccttgac aaatctatcg 3000

 gtgcttggta ccagcatgag ctaactttat ggctcaaacc aataggacaa 3050

 tttgctgagg tctgagagga ctccctccag aaaatccctg atctcttaaa 3100

 atttggta 3108

<210> 5238
<211> 343
<212> PRT
<213> Homo sapien

<400> 5238
 Met Asp Asn Gln Ala Glu Arg Glu Ser Glu Ala Gly Val Gly Leu
   1               5                  10                  15

 Gln Arg Asp Glu Asp Asp Ala Pro Leu Cys Glu Asp Val Glu Leu
                  20                  25                  30

 Gln Asp Gly Asp Leu Ser Pro Glu Glu Lys Ile Phe Leu Arg Glu
                  35                  40                  45

 Phe Pro Arg Leu Lys Glu Asp Leu Lys Gly Asn Ile Asp Lys Leu
                  50                  55                  60

 Arg Ala Leu Ala Asp Asp Ile Asp Lys Thr His Lys Lys Phe Thr
                  65                  70                  75

 Lys Ala Asn Met Val Ala Thr Ser Thr Ala Val Ile Ser Gly Val
                  80                  85                  90

 Met Ser Leu Leu Gly Leu Ala Leu Ala Pro Ala Thr Gly Gly Gly
                  95                 100                 105

 Ser Leu Leu Leu Ser Thr Ala Gly Gln Gly Leu Ala Thr Ala Ala
                 110                 115                 120

 Gly Val Thr Ser Ile Val Ser Gly Thr Leu Glu Arg Ser Lys Asn
                 125                 130                 135

 Lys Glu Ala Gln Ala Arg Ala Glu Asp Ile Leu Pro Thr Tyr Asp
                 140                 145                 150

 Gln Glu Asp Arg Glu Asp Glu Glu Glu Lys Ala Asp Tyr Val Thr
                 155                 160                 165

 Ala Ala Gly Lys Ile Ile Tyr Asn Leu Arg Asn Thr Leu Lys Tyr
                 170                 175                 180

 Ala Lys Lys Asn Val Arg Ala Phe Trp Lys Leu Arg Ala Asn Pro
                 185                 190                 195

 Arg Leu Ala Asn Ala Thr Lys Arg Leu Leu Thr Thr Gly Gln Val
                 200                 205                 210

 Ser Ser Arg Ser Arg Val Gln Val Gln Lys Ala Phe Ala Gly Thr
                 215                 220                 225

 Thr Leu Ala Met Thr Lys Asn Ala Arg Val Leu Gly Gly Val Met
                 230                 235                 240

 Ser Ala Phe Ser Leu Gly Tyr Asp Leu Ala Thr Leu Ser Lys Glu
                 245                 250                 255

 Trp Lys His Leu Lys Glu Gly Ala Arg Thr Lys Phe Ala Glu Glu
                 260                 265                 270

 Leu Arg Ala Lys Ala Leu Glu Leu Glu Arg Lys Leu Thr Glu Leu
                 275                 280                 285

 Thr Gln Leu Tyr Lys Ser Leu Gln Gln Lys Val Arg Ser Arg Ala
                 290                 295                 300

 Arg Gly Val Gly Lys Asp Leu Thr Gly Thr Cys Glu Thr Glu Ala
                 305                 310                 315

 Tyr Trp Lys Glu Leu Arg Glu His Val Trp Met Trp Leu Trp Leu
                 320                 325                 330

 Cys Val Cys Leu Cys Val Cys Val Tyr Val Gln Phe Thr
                 335                 340

<210> 5239
<211> 1379
<212> DNA
<213> Homo sapien

<400> 5239
 gcggccggga ggccggagca gcacggccgc aggacctgaa gctccggctg 50

 cgtcttcccg cagcgctacc cgccatgcgc ctgccgcgcc gggccgcgct 100

 ggggctcctg ccgcttctgc tgctgctgcc gcccgcgccg gaggccgcca 150

 agaagccgac gccctgccac cggtgccggg ggctggtgga caagtttaac 200

 caggggatgg tggacaccgc aaagaagaac tttggcggcg ggaacacggc 250

 ttgggaggaa aagacgctgt ccaagtacga gtccagcgag attcgcctgc 300

 tggagatcct ggaggggctg tgcgagagca gcgacttcga atgcaaccag 350

 atgctagagg cgcaggagga gcacctggag gcctggtggc tgcagctgaa 400

 gagcgaatat cctgacttat tcgagtggtt ttgtgtgaag acactgaaag 450

 tgtgctgctc tccaggaacc tacggtcccg actgtctcgc atgccagggc 500

 ggatcccaga ggccctgcag cgggaatggc cactgcagcg gagatgggag 550

 cagacagggc gacgggtcct gccggtgcca catggggtac cagggcccgc 600

 tgtgcactga ctgcatggac ggctacttca gctcgctccg gaacgagacc 650

 cacagcatct gcacagcctg tgacgagtcc tgcaagacgt gctcgggcct 700

 gaccaacaga gactgcggcg agtgtgaagt gggctgggtg ctggacgagg 750

 gcgcctgtgt ggatgtggac gagtgtgcgg ccgagccgcc tccctgcagc 800

 gctgcgcagt tctgtaagaa cgccaacggc tcctacacgt gcgaagagtg 850

 tgactccagc tgtgtgggct gcacagggga aggcccagga aactgtaaag 900

 agtgtatctc tggctacgcg agggagcacg gacagtgtgc agatgtggac 950

 gagtgcgcac tagcagaaaa aacctgtgtg aggaaaaacg aaaactgcta 1000

 caatactcca gggagctacg tctgtgtgtg tcctgacggc ttcgaaggaa 1050

 cggaagatgc ctgtgtgccg ccggcagagg ctgaagccac agaaggagaa 1100

 agcccgacac agctgccctc ccgcgaagac ctgtaatgtg ccggacttac 1150

 cctttaaatt attcagaagg atgtcccgtg gaaaatgtgg ccctgaggat 1200

 gccgtctcct gcagtggaca gcggcgggga gaggctgcct gctctctaac 1250

 ggttgattct catttgtccc ttaaacagct gcatttcttg gttgttctta 1300

 aacagacttg tatattttga tacagttctt tgtaataaaa ttgaccattg 1350

 taggtaaaaa aaaaaaaaaa aaaaaaaaa 1379

<210> 5240
<211> 353
<212> PRT
<213> Homo sapien

<400> 5240
 Met Arg Leu Pro Arg Arg Ala Ala Leu Gly Leu Leu Pro Leu Leu
   1               5                  10                  15

 Leu Leu Leu Pro Pro Ala Pro Glu Ala Ala Lys Lys Pro Thr Pro
                  20                  25                  30

 Cys His Arg Cys Arg Gly Leu Val Asp Lys Phe Asn Gln Gly Met
                  35                  40                  45

 Val Asp Thr Ala Lys Lys Asn Phe Gly Gly Gly Asn Thr Ala Trp
                  50                  55                  60

 Glu Glu Lys Thr Leu Ser Lys Tyr Glu Ser Ser Glu Ile Arg Leu
                  65                  70                  75

 Leu Glu Ile Leu Glu Gly Leu Cys Glu Ser Ser Asp Phe Glu Cys
                  80                  85                  90

 Asn Gln Met Leu Glu Ala Gln Glu Glu His Leu Glu Ala Trp Trp
                  95                 100                 105

 Leu Gln Leu Lys Ser Glu Tyr Pro Asp Leu Phe Glu Trp Phe Cys
                 110                 115                 120

 Val Lys Thr Leu Lys Val Cys Cys Ser Pro Gly Thr Tyr Gly Pro
                 125                 130                 135

 Asp Cys Leu Ala Cys Gln Gly Gly Ser Gln Arg Pro Cys Ser Gly
                 140                 145                 150

 Asn Gly His Cys Ser Gly Asp Gly Ser Arg Gln Gly Asp Gly Ser
                 155                 160                 165

 Cys Arg Cys His Met Gly Tyr Gln Gly Pro Leu Cys Thr Asp Cys
                 170                 175                 180

 Met Asp Gly Tyr Phe Ser Ser Leu Arg Asn Glu Thr His Ser Ile
                 185                 190                 195

 Cys Thr Ala Cys Asp Glu Ser Cys Lys Thr Cys Ser Gly Leu Thr
                 200                 205                 210

 Asn Arg Asp Cys Gly Glu Cys Glu Val Gly Trp Val Leu Asp Glu
                 215                 220                 225

 Gly Ala Cys Val Asp Val Asp Glu Cys Ala Ala Glu Pro Pro Pro
                 230                 235                 240

 Cys Ser Ala Ala Gln Phe Cys Lys Asn Ala Asn Gly Ser Tyr Thr
                 245                 250                 255

 Cys Glu Glu Cys Asp Ser Ser Cys Val Gly Cys Thr Gly Glu Gly
                 260                 265                 270

 Pro Gly Asn Cys Lys Glu Cys Ile Ser Gly Tyr Ala Arg Glu His
                 275                 280                 285

 Gly Gln Cys Ala Asp Val Asp Glu Cys Ala Leu Ala Glu Lys Thr
                 290                 295                 300

 Cys Val Arg Lys Asn Glu Asn Cys Tyr Asn Thr Pro Gly Ser Tyr
                 305                 310                 315

 Val Cys Val Cys Pro Asp Gly Phe Glu Gly Thr Glu Asp Ala Cys
                 320                 325                 330

 Val Pro Pro Ala Glu Ala Glu Ala Thr Glu Gly Glu Ser Pro Thr
                 335                 340                 345

 Gln Leu Pro Ser Arg Glu Asp Leu
                 350

<210> 5241
<211> 2961
<212> DNA
<213> Homo sapien

<400> 5241
 acatactcca ccttcaaaaa gtacatcaat attatatcat taaggaaata 50

 gtaaccttct cttctccaat atgcatgaca tttttggaca atgcaattgt 100

 ggcactggca cttatttcag tgaagaaaaa ctttgtggtt ctatggcatt 150

 catcatttga caaatgcaag catcttcctt atcaatcagc tcctattgaa 200

 cttactagca ctgactgtgg aatccttaag ggcccattac atttctgaag 250

 aagaaagcta agatgaagga catgccactc cgaattcatg tgctacttgg 300

 cctagctatc actacactag tacaagctgt agataaaaaa gtggattgtc 350

 cacggttatg tacgtgtgaa atcaggcctt ggtttacacc cagatccatt 400

 tatatggaag catctacagt ggattgtaat gatttaggtc ttttaacttt 450

 cccagccaga ttgccagcta acacacagat tcttctccta cagactaaca 500

 atattgcaaa aattgaatac tccacagact ttccagtaaa ccttactggc 550

 ctggatttat ctcaaaacaa tttatcttca gtcaccaata ttaatgtaaa 600

 aaagatgcct cagctccttt ctgtgtacct agaggaaaac aaacttactg 650

 aactgcctga aaaatgtctg tccgaactga gcaacttaca agaactctat 700

 attaatcaca acttgctttc tacaatttca cctggagcct ttattggcct 750

 acataatctt cttcgacttc atctcaattc aaatagattg cagatgatca 800

 acagtaagtg gtttgatgct cttccaaatc tagagattct gatgattggg 850

 gaaaatccaa ttatcagaat caaagacatg aactttaagc ctcttatcaa 900

 tcttcgcagc ctggttatag ctggtataaa cctcacagaa ataccagata 950

 acgccttggt tggactggaa aacttagaaa gcatctcttt ttacgataac 1000

 aggcttatta aagtacccca tgttgctctt caaaaagttg taaatctcaa 1050

 atttttggat ctaaataaaa atcctattaa tagaatacga aggggtgatt 1100

 ttagcaatat gctacactta aaagagttgg ggataaataa tatgcctgag 1150

 ctgatttcca tcgatagtct tgctgtggat aacctgccag atttaagaaa 1200

 aatagaagct actaacaacc ctagattgtc ttacattcac cccaatgcat 1250

 ttttcagact ccccaagctg gaatcactca tgctgaacag caatgctctc 1300

 agtgccctgt accatggtac cattgagtct ctgccaaacc tcaaggaaat 1350

 cagcatacac agtaacccca tcaggtgtga ctgtgtcatc cgttggatga 1400

 acatgaacaa aaccaacatt cgattcatgg agccagattc actgttttgc 1450

 gtggacccac ctgaattcca aggtcagaat gttcggcaag tgcatttcag 1500

 ggacatgatg gaaatttgtc tccctcttat agctcctgag agctttcctt 1550

 ctaatctaaa tgtagaagct gggagctatg tttcctttca ctgtagagct 1600

 actgcagaac cacagcctga aatctactgg ataacacctt ctggtcaaaa 1650

 actcttgcct aataccctga cagacaagtt ctatgtccat tctgagggaa 1700

 cactagatat aaatggcgta actcccaaag aagggggttt atatacttgt 1750

 atagcaacta acctagttgg cgctgacttg aagtctgtta tgatcaaagt 1800

 ggatggatct tttccacaag ataacaatgg ctctttgaat attaaaataa 1850

 gagatattca ggccaattca gttttggtgt cctggaaagc aagttctaaa 1900

 attctcaaat ctagtgttaa atggacagcc tttgtcaaga ctgaaaattc 1950

 tcatgctgcg caaagtgctc gaataccatc tgatgtcaag gtatataatc 2000

 ttactcatct gaatccatca actgagtata aaatttgtat tgatattccc 2050

 accatctatc agaaaaacag aaaaaaatgt gtaaatgtca ccaccaaagg 2100

 tttgcaccct gatcaaaaag agtatgaaaa gaataatacc acaacactta 2150

 tggcctgtct tggaggcctt ctggggatta ttggtgtgat atgtcttatc 2200

 agctgcctct ctccagaaat gaactgtgat ggtggacaca gctatgtgag 2250

 gaattactta cagaaaccaa cctttgcatt aggtgagctt tatcctcctc 2300

 tgataaatct ctgggaagca ggaaaagaaa aaagtacatc actgaaagta 2350

 aaagcaactg ttataggttt accaacaaat atgtcctaaa aaccaccaag 2400

 gaaacctact ccaaaaatga acaaaaaaaa aaaaaagcga aagactgcag 2450

 ttgtgctaaa aacaaaacaa aacaaacaaa caaacaaaaa agtaaaaaaa 2500

 gattactttc gagagagaag tttaagcttc accaatgctg ctcctgacca 2550

 atggaaatat gtacaacttc agcattttaa gtaactggct tcaaggggta 2600

 ctgtggcaac caaataaaat aactccattt tctaaaactt tcatgtaact 2650

 tttatgtctg gactacagtt caagtggaca aaaacatttc tgtatttttt 2700

 ttaagtaaat aagagtagtt gaactgagca atacctcctc ctgtgttgta 2750

 ttacacatat tagccacgag tttttgcagt gaccagataa acttgaattg 2800

 acacgtggtg taataaaatg gacaaattct gtagagtaga cacagtgagt 2850

 atgtggacct cttttataag gaaaaataca ttttggatta aaatcaattg 2900

 cttctgtctt gttttgtttc taaataaaga ataatttctg ggaaaaaaaa 2950

 aaaaaaaaaa a 2961

<210> 5242
<211> 708
<212> PRT
<213> Homo sapien

<400> 5242
 Met Lys Asp Met Pro Leu Arg Ile His Val Leu Leu Gly Leu Ala
   1               5                  10                  15

 Ile Thr Thr Leu Val Gln Ala Val Asp Lys Lys Val Asp Cys Pro
                  20                  25                  30

 Arg Leu Cys Thr Cys Glu Ile Arg Pro Trp Phe Thr Pro Arg Ser
                  35                  40                  45

 Ile Tyr Met Glu Ala Ser Thr Val Asp Cys Asn Asp Leu Gly Leu
                  50                  55                  60

 Leu Thr Phe Pro Ala Arg Leu Pro Ala Asn Thr Gln Ile Leu Leu
                  65                  70                  75

 Leu Gln Thr Asn Asn Ile Ala Lys Ile Glu Tyr Ser Thr Asp Phe
                  80                  85                  90

 Pro Val Asn Leu Thr Gly Leu Asp Leu Ser Gln Asn Asn Leu Ser
                  95                 100                 105

 Ser Val Thr Asn Ile Asn Val Lys Lys Met Pro Gln Leu Leu Ser
                 110                 115                 120

 Val Tyr Leu Glu Glu Asn Lys Leu Thr Glu Leu Pro Glu Lys Cys
                 125                 130                 135

 Leu Ser Glu Leu Ser Asn Leu Gln Glu Leu Tyr Ile Asn His Asn
                 140                 145                 150

 Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe Ile Gly Leu His Asn
                 155                 160                 165

 Leu Leu Arg Leu His Leu Asn Ser Asn Arg Leu Gln Met Ile Asn
                 170                 175                 180

 Ser Lys Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile Leu Met Ile
                 185                 190                 195

 Gly Glu Asn Pro Ile Ile Arg Ile Lys Asp Met Asn Phe Lys Pro
                 200                 205                 210

 Leu Ile Asn Leu Arg Ser Leu Val Ile Ala Gly Ile Asn Leu Thr
                 215                 220                 225

 Glu Ile Pro Asp Asn Ala Leu Val Gly Leu Glu Asn Leu Glu Ser
                 230                 235                 240

 Ile Ser Phe Tyr Asp Asn Arg Leu Ile Lys Val Pro His Val Ala
                 245                 250                 255

 Leu Gln Lys Val Val Asn Leu Lys Phe Leu Asp Leu Asn Lys Asn
                 260                 265                 270

 Pro Ile Asn Arg Ile Arg Arg Gly Asp Phe Ser Asn Met Leu His
                 275                 280                 285

 Leu Lys Glu Leu Gly Ile Asn Asn Met Pro Glu Leu Ile Ser Ile
                 290                 295                 300

 Asp Ser Leu Ala Val Asp Asn Leu Pro Asp Leu Arg Lys Ile Glu
                 305                 310                 315

 Ala Thr Asn Asn Pro Arg Leu Ser Tyr Ile His Pro Asn Ala Phe
                 320                 325                 330

 Phe Arg Leu Pro Lys Leu Glu Ser Leu Met Leu Asn Ser Asn Ala
                 335                 340                 345

 Leu Ser Ala Leu Tyr His Gly Thr Ile Glu Ser Leu Pro Asn Leu
                 350                 355                 360

 Lys Glu Ile Ser Ile His Ser Asn Pro Ile Arg Cys Asp Cys Val
                 365                 370                 375

 Ile Arg Trp Met Asn Met Asn Lys Thr Asn Ile Arg Phe Met Glu
                 380                 385                 390

 Pro Asp Ser Leu Phe Cys Val Asp Pro Pro Glu Phe Gln Gly Gln
                 395                 400                 405

 Asn Val Arg Gln Val His Phe Arg Asp Met Met Glu Ile Cys Leu
                 410                 415                 420

 Pro Leu Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu Asn Val Glu
                 425                 430                 435

 Ala Gly Ser Tyr Val Ser Phe His Cys Arg Ala Thr Ala Glu Pro
                 440                 445                 450

 Gln Pro Glu Ile Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu Leu
                 455                 460                 465

 Pro Asn Thr Leu Thr Asp Lys Phe Tyr Val His Ser Glu Gly Thr
                 470                 475                 480

 Leu Asp Ile Asn Gly Val Thr Pro Lys Glu Gly Gly Leu Tyr Thr
                 485                 490                 495

 Cys Ile Ala Thr Asn Leu Val Gly Ala Asp Leu Lys Ser Val Met
                 500                 505                 510

 Ile Lys Val Asp Gly Ser Phe Pro Gln Asp Asn Asn Gly Ser Leu
                 515                 520                 525

 Asn Ile Lys Ile Arg Asp Ile Gln Ala Asn Ser Val Leu Val Ser
                 530                 535                 540

 Trp Lys Ala Ser Ser Lys Ile Leu Lys Ser Ser Val Lys Trp Thr
                 545                 550                 555

 Ala Phe Val Lys Thr Glu Asn Ser His Ala Ala Gln Ser Ala Arg
                 560                 565                 570

 Ile Pro Ser Asp Val Lys Val Tyr Asn Leu Thr His Leu Asn Pro
                 575                 580                 585

 Ser Thr Glu Tyr Lys Ile Cys Ile Asp Ile Pro Thr Ile Tyr Gln
                 590                 595                 600

 Lys Asn Arg Lys Lys Cys Val Asn Val Thr Thr Lys Gly Leu His
                 605                 610                 615

 Pro Asp Gln Lys Glu Tyr Glu Lys Asn Asn Thr Thr Thr Leu Met
                 620                 625                 630

 Ala Cys Leu Gly Gly Leu Leu Gly Ile Ile Gly Val Ile Cys Leu
                 635                 640                 645

 Ile Ser Cys Leu Ser Pro Glu Met Asn Cys Asp Gly Gly His Ser
                 650                 655                 660

 Tyr Val Arg Asn Tyr Leu Gln Lys Pro Thr Phe Ala Leu Gly Glu
                 665                 670                 675

 Leu Tyr Pro Pro Leu Ile Asn Leu Trp Glu Ala Gly Lys Glu Lys
                 680                 685                 690

 Ser Thr Ser Leu Lys Val Lys Ala Thr Val Ile Gly Leu Pro Thr
                 695                 700                 705

 Asn Met Ser


<210> 5243
<211> 1772
<212> DNA
<213> Homo sapien

<400> 5243
 agcgggtgcg gtccgtcggt ggcctagaga tgctgctgcc gcggttgcag 50

 ttgtcgcgca cgcctctgcc cgccagcccg ctccaccgcc gtagcgcccg 100

 agtgtcgggg ggcgcacccg agtcgggcca tgaggccggg aaccgcgcta 150

 caggcggtgc tgctggccgt gctgctggtg gggctgcggg ccgcgacggg 200

 tcgcctgctg agtgggcagc cagtctgccg gggagggaca cagaggcctt 250

 gttataaagt catttacttc catgatactt ctcgaagact gaactttgag 300

 gaagccaaag aagcctgcag gagggatgga ggccagctag tcagcatcga 350

 gtctgaagat gaacagaaac tgatagaaaa gttcattgaa aacctcttgc 400

 catctgatgg tgacttctgg attgggctca ggaggcgtga ggagaaacaa 450

 agcaatagca cagcctgcca ggacctttat gcttggactg atggcagcat 500

 atcacaattt aggaactggt atgtggatga gccgtcctgc ggcagcgagg 550

 tctgcgtggt catgtaccat cagccatcgg cacccgctgg catcggaggc 600

 ccctacatgt tccagtggaa tgatgaccgg tgcaacatga agaacaattt 650

 catttgcaaa tattctgatg agaaaccagc agttccttct agagaagctg 700

 aaggtgagga aacagagctg acaacacctg tacttccaga agaaacacag 750

 gaagaagatg ccaaaaaaac atttaaagaa agtagagaag ctgccttgaa 800

 tctggcctac atcctaatcc ccagcattcc ccttctcctc ctccttgtgg 850

 tcaccacagt tgtatgttgg gtttggatct gtagaaaaag aaaacgggag 900

 cagccagacc ctagcacaaa gaagcaacac accatctggc cctctcctca 950

 ccagggaaac agcccggacc tagaggtcta caatgtcata agaaaacaaa 1000

 gcgaagctga cttagctgag acccggccag acctgaagaa tatttcattc 1050

 cgagtgtgtt cgggagaagc cactcccgat gacatgtctt gtgactatga 1100

 caacatggct gtgaacccat cagaaagtgg gtttatgact ctggtgagcg 1150

 tggagagtgg atttgtgacc aatgacattt atgagttctc cccagaccaa 1200

 atggggagga gtaaggagtc tggatgggtg gaaaatgaaa tatatggtta 1250

 ttaggacata taaaaaactg aaactgacaa caatggaaaa gaaatgataa 1300

 gcaaaatcct cttattttct ataaggaaaa tacacagaag gtctatgaac 1350

 aagcttagat caggtcctgt ggatgagcat gtggtcccca cgacctcctg 1400

 ttggaccccc acgttttggc tgtatccttt atcccagcca gtcatccagc 1450

 tcgaccttat gagaaggtac cttgcccagg tctggcacat agtagagtct 1500

 caataaatgt cacttggttg gttgtatcta acttttaagg gacagagctt 1550

 tacctggcag tgataaagat gggctgtgga gcttggaaaa ccacctctgt 1600

 tttccttgct ctatacagca gcacatatta tcatacagac agaaaatcca 1650

 gaatcttttc aaagcccaca tatggtagca caggttggcc tgtgcatcgg 1700

 caattctcat atctgttttt ttcaaagaat aaaatcaaat aaagagcagg 1750

 aaacagaaaa aaaaaaaaaa aa 1772

<210> 5244
<211> 374
<212> PRT
<213> Homo sapien

<400> 5244
 Met Arg Pro Gly Thr Ala Leu Gln Ala Val Leu Leu Ala Val Leu
   1               5                  10                  15

 Leu Val Gly Leu Arg Ala Ala Thr Gly Arg Leu Leu Ser Gly Gln
                  20                  25                  30

 Pro Val Cys Arg Gly Gly Thr Gln Arg Pro Cys Tyr Lys Val Ile
                  35                  40                  45

 Tyr Phe His Asp Thr Ser Arg Arg Leu Asn Phe Glu Glu Ala Lys
                  50                  55                  60

 Glu Ala Cys Arg Arg Asp Gly Gly Gln Leu Val Ser Ile Glu Ser
                  65                  70                  75

 Glu Asp Glu Gln Lys Leu Ile Glu Lys Phe Ile Glu Asn Leu Leu
                  80                  85                  90

 Pro Ser Asp Gly Asp Phe Trp Ile Gly Leu Arg Arg Arg Glu Glu
                  95                 100                 105

 Lys Gln Ser Asn Ser Thr Ala Cys Gln Asp Leu Tyr Ala Trp Thr
                 110                 115                 120

 Asp Gly Ser Ile Ser Gln Phe Arg Asn Trp Tyr Val Asp Glu Pro
                 125                 130                 135

 Ser Cys Gly Ser Glu Val Cys Val Val Met Tyr His Gln Pro Ser
                 140                 145                 150

 Ala Pro Ala Gly Ile Gly Gly Pro Tyr Met Phe Gln Trp Asn Asp
                 155                 160                 165

 Asp Arg Cys Asn Met Lys Asn Asn Phe Ile Cys Lys Tyr Ser Asp
                 170                 175                 180

 Glu Lys Pro Ala Val Pro Ser Arg Glu Ala Glu Gly Glu Glu Thr
                 185                 190                 195

 Glu Leu Thr Thr Pro Val Leu Pro Glu Glu Thr Gln Glu Glu Asp
                 200                 205                 210

 Ala Lys Lys Thr Phe Lys Glu Ser Arg Glu Ala Ala Leu Asn Leu
                 215                 220                 225

 Ala Tyr Ile Leu Ile Pro Ser Ile Pro Leu Leu Leu Leu Leu Val
                 230                 235                 240

 Val Thr Thr Val Val Cys Trp Val Trp Ile Cys Arg Lys Arg Lys
                 245                 250                 255

 Arg Glu Gln Pro Asp Pro Ser Thr Lys Lys Gln His Thr Ile Trp
                 260                 265                 270

 Pro Ser Pro His Gln Gly Asn Ser Pro Asp Leu Glu Val Tyr Asn
                 275                 280                 285

 Val Ile Arg Lys Gln Ser Glu Ala Asp Leu Ala Glu Thr Arg Pro
                 290                 295                 300

 Asp Leu Lys Asn Ile Ser Phe Arg Val Cys Ser Gly Glu Ala Thr
                 305                 310                 315

 Pro Asp Asp Met Ser Cys Asp Tyr Asp Asn Met Ala Val Asn Pro
                 320                 325                 330

 Ser Glu Ser Gly Phe Met Thr Leu Val Ser Val Glu Ser Gly Phe
                 335                 340                 345

 Val Thr Asn Asp Ile Tyr Glu Phe Ser Pro Asp Gln Met Gly Arg
                 350                 355                 360

 Ser Lys Glu Ser Gly Trp Val Glu Asn Glu Ile Tyr Gly Tyr
                 365                 370

<210> 5245
<211> 2190
<212> DNA
<213> Homo sapien

<400> 5245
 ggcacgaggg acctctctgt gcagtatcct ccagagaacc tgagagtgat 50

 ggtttcccaa gcaaacagga cagtcctgga aaaccttggg aacggcacgt 100

 ctctcccagt actggagggc caaagcctgt gcctggtctg tgtcacacac 150

 agcagccccc cagccaggct gagctggacc cagaggggac aggttctgag 200

 cccctcccag ccctcagacc ccggggtcct ggagctgcct cgggttcaag 250

 tggagcacga aggagagttc acctgccacg ctcggcaccc actgggctcc 300

 cagcacgtct ctctcagcct ctccgtgcac tactccccga agctgctggg 350

 cccctcctgc tcctgggagg ctgagggtct gcactgcagc tgctcctccc 400

 aggccagccc ggccccctct ctgcgctggt ggcttgggga ggagctgctg 450

 gaggggaaca gcagccagga ctccttcgag gtcaccccca gctcagccgg 500

 gccctgggcc aacagctccc tgagcctcca tggagggctc agctccggcc 550

 tcaggctccg ctgtgaggcc tggaacgtcc atggggccca gagtggatcc 600

 atcctgcagc tgccagataa gaagggactc atctcaacgg cattctccaa 650

 cggagcgttt ctgggaatcg gcatcacggc tcttcttttc ctctgcctgg 700

 ccctgatcat catgaagatt ctaccgaaga gacggactca gacagaaacc 750

 ccgaggccca ggttctcccg gcacagcacg atcctggatt acatcaatgt 800

 ggtcccgacg gctggccccc tggctcagaa gcggaatcag aaagccacac 850

 caaacagtcc tcggacccct cttccaccag gtgctccctc cccagaatca 900

 aagaagaacc agaaaaagca gtatcagttg cccagtttcc cagaacccaa 950

 atcatccact caagccccag aatcccagga gagccaagag gagctccatt 1000

 atgccacgct caacttccca ggcgtcagac ccaggcctga ggcccggatg 1050

 cccaagggca cccaggcgga ttatgcagaa gtcaagttcc aatgagggtc 1100

 tcttaggctt taggactggg acttcggcta gggaggaagg tagagtaaga 1150

 ggttgaagat aacagagtgc aaagtttcct tctctccctc tctctctctc 1200

 tttctctctc tctctctctt tctctctctt ttaaaaaaac atctggccag 1250

 ggcacagtgg ctcacgcctg taatcccagc actttgggag gttgaggtgg 1300

 gcagatcgcc tgaggtcggg agttcgagac cagcctggcc aacttggtga 1350

 aaccccgtct ctactaaaaa tacaaaaatt agctgggcat ggtggcaggc 1400

 gcctgtaatc ctacctactt gggaagctga ggcaggagaa tcacttgaac 1450

 ctgggagacg gaggttgcag tgagccaaga tcacaccatt gcatgccagc 1500

 ctgggcaaca aagcgagact ccatctcaaa aaaaaaatcc tccaaatggg 1550

 ttgggtgtct gtaatcccag cactttggga ggctaaggtg ggtggattgc 1600

 ttgagcccag gagttcgaga ccagcctggg caacatggtg aaaccccatc 1650

 tctacaaaaa atacaaaaca tagctgggct tggtggtgtg tgcctgtagt 1700

 cccagctgtc agacatttaa accagagcaa ctccatctgg aataggagct 1750

 gaatacaatg aggctgagac ctactgggct gcattctcag acagtggagg 1800

 cattctaagt cacaggatga gacaggaggt ccgtacaaga tacaggtcat 1850

 aaagactttg ctgataaaac agattgcagt aaagaagcca accaaatccc 1900

 accaaaacca agttggccac gagagtgacc tctggtcgtc ctcactgcta 1950

 cactcctgac agcaccatga cagtttacaa atgccatggc aacatcagga 2000

 agttacccga tatgtcccaa aagggggagg aatgaataat ccaccccttg 2050

 tttagcaaat aagcaagaaa taaccataaa agtgggcaac cagcagctct 2100

 aggcgctgct cttgtctatg gagtagccat tcttttgttc ctttactttc 2150

 ttaataaact tgctttcacc ttaaaaaaaa aaaaaaaaaa 2190

<210> 5246
<211> 4689
<212> DNA
<213> Homo sapien

<400> 5246
 ccggccgcgt cccgcccgct ccccggcacc agaagttcct ctgcgcgtcc 50

 gacggcgaca tgggcgtccc cacggccctg gaggccggca gctggcgctg 100

 gggatccctg ctcttcgctc tcttcctggc tgcgtcccta ggtccggtgg 150

 cagccttcaa ggtcgccacg ccgtattccc tgtatgtctg tcccgagggg 200

 cagaacgtca ccctcacctg caggctcttg ggccctgtgg acaaagggca 250

 cgatgtgacc ttctacaaga cgtggtaccg cagctcgagg ggcgaggtgc 300

 agacctgctc agagcgccgg cccatccgca acctcacgtt ccaggacctt 350

 cacctgcacc atggaggcca ccaggctgcc aacaccagcc acgacctggc 400

 tcagcgccac gggctggagt cggcctccga ccaccatggc aacttctcca 450

 tcaccatgcg caacctgacc ctgctggata gcggcctcta ctgctgcctg 500

 gtggtggaga tcaggcacca ccactcggag cacagggtcc atggtgccat 550

 ggagctgcag gtgcagacag gcaaagatgc accatccaac tgtgtggtgt 600

 acccatcctc ctcccaggag agtgaaaaca tcacggctgc agccctggct 650

 acgggtgcct gcatcgtagg aatcctctgc ctccccctca tcctgctcct 700

 ggtctacaag caaaggcagg cagcctccaa ccgccgtgcc caggagctgg 750

 tgcggatgga cagcaacatt caagggattg aaaaccccgg ctttgaagcc 800

 tcaccacctg cccaggggat acccgaggcc aaagtcaggc accccctgtc 850

 ctatgtggcc cagcggcagc cttctgagtc tgggcggcat ctgctttcgg 900

 agcccagcac ccccctgtct cctccaggcc ccggagacgt cttcttccca 950

 tccctggacc ctgtccctga ctctccaaac tttgaggtca tctagcccag 1000

 ctgggggaca gtgggctgtt gtggctgggt ctggggcagg tgcatttgag 1050

 ccagggctgg ctctgtgagt ggcctccttg gcctcggccc tggttccctc 1100

 cctcctgctc tgggctcaga tactgtgaca tcccagaagc ccagcccctc 1150

 aacccctctg gatgctacat ggggatgctg gacggctcag cccctgttcc 1200

 aaggattttg gggtgctgag attctcccct agagacctga aattcaccag 1250

 ctacagatgc caaatgactt acatcttaag aagtctcaga acgtccagcc 1300

 cttcagcagc tctcgttctg agacatgagc cttgggatgt ggcagcatca 1350

 gtgggacaag atggacactg ggccaccctc ccaggcacca gacacagggc 1400

 acggtggaga gacttctccc ccgtggccgc cttggctccc ccgttttgcc 1450

 cgaggctgct cttctgtcag acttcctctt tgtaccacag tggctctggg 1500

 gccaggcctg cctgcccact ggccatcgcc accttaccca gctgcctcct 1550

 accagcagtt tctctgaaga tctgtcaaca ggttaagtca atctggggct 1600

 tccactgcct gcattccagt ccccagagct tggtggtccc gaaacgggaa 1650

 gtacatattg gggcatggtg gcctccgtga gcaaatggtg tcttgggcaa 1700

 tctgaggcca ggacagatgt tgccccaccc actggagatg gtgctgaggg 1750

 aggtgggtgg ggccttctgg gaaggtgagt ggagaggggc acctgccccc 1800

 cgccctcccc atcccctact cccactgctc agcgcgggcc attgcaaggg 1850

 tgccacacaa tgtcttgtcc accctgggac acttctgagt atgaagcggg 1900

 atgctattaa aaactacatg gggaaacagg tgcaaaccct ggagatggat 1950

 tgtaagagcc agtttaaatc tgcactctgc tgctcctccc ccacccccac 2000

 cttccactcc atacaatctg ggcctggtgg agtcttcgct tcagagccat 2050

 tcggccaggt gcgggtgatg ttcccatctc ctgcttgtgg gcatgccctg 2100

 gctttgtttt tatacacata ggcaaggtga gtcctctgtg gaattgtgat 2150

 tgaaggattt taaagcaggg gaggagagta gggggcatct ctgtacactc 2200

 tgggggtaaa acagggaagg cagtgcctga gcatggggac aggtgaggtg 2250

 gggctgggca gaccccctgt agcgtttagc aggatggggg ccccaggtac 2300

 tgtggagagc atagtccagc ctgggcattt gtctcctagc agcctacact 2350

 ggctctgctg agctgggcct gggtgctgaa agccaggatt tggggctagg 2400

 cgggaagatg ttcgcccaat tgcttggggg gttgggggga tggaaaaggg 2450

 gagcacctct aggctgcctg gcagcagtga gccctgggcc tgtggctaca 2500

 gccagggaac cccacctgga cacatggccc tgcttctaag ccccccagtt 2550

 aggcccaaag gaatggtcca ctgagggcct cctgctctgc ctgggctggg 2600

 ccaggggctt tgaggagagg gtaaacatag gcccggagat ggggctgaca 2650

 cctcgagtgg ccagaatatg cccaaacccc ggcttctccc ttgtccctag 2700

 gcagaggggg gtcccttctt ttgttccctc tggtcaccac aatgcttgat 2750

 gccagctgcc ataggaagag ggtgctggct ggccatggtg gcacacacct 2800

 gtcctcccag cactttgcag ggctgaggtg gaaggaccgc ttaagcccag 2850

 gtgttcaagg ctgctgtgag ctgtgttcga gccactacac tccagcctgg 2900

 ggacggagca aaactttgcc tcaaaacaaa ttttaaaaag aaagaaagaa 2950

 ggaaagaggg tatgtttttc acaattcatg ggggcctgca tggcaggagt 3000

 ggggacagga cacctgctgt tcctggagtc gaaggacaag cccacagccc 3050

 agattccggt tctcccaact caggaagagc atgccctgcc ctctggggag 3100

 gctggcctgg ccccagccct cagctgctga ccttgaggca gagacaactt 3150

 ctaagaattt ggctgccaga ccccaggcct ggctgctgct gtgtggagag 3200

 ggaggcggcc cgcggcagaa cagccaccgc acttcctcct cagcttcctc 3250

 tggtgcggcc ctgccctctc ttctctggac ccttttacaa ctgaacgcat 3300

 ctgggcttcg tggtttcctg ttttcagcga aatttactct gagctcccag 3350

 ttccatcttc atccatggcc acaggccctg cctacaacgc actagggacg 3400

 tccctccctg ctgctgctgg ggaggggcag gctgctggag ccgccctctg 3450

 agttgcccgg gatggtagtg cctctgatgc cagccctggt ggctgtgggc 3500

 tggggtgcat gggagagctg ggtgcgagaa catggcgcct ccagggggcg 3550

 ggaggagcac taggggctgg ggcaggaggc tcctggagcg ctggattcgt 3600

 ggcacagtct gaggccctga gagggaaatc catgctttta agaactaatt 3650

 cattgttagg agatcaatca ggaattaggg gccatcttac ctatctcctg 3700

 acattcacag tttaatagag acttcctgcc tttattccct cccagggaga 3750

 ggctgaagga atggaattga aagcaccatt tggagggttt tgctgacaca 3800

 gcggggaccg ctcagcactc cctaaaaaca caccatggag gccactggtg 3850

 actgctggtg ggcaggctgg ccctgcctgg gggagtccgt ggcgatgggc 3900

 gctggggtgg aggtgcagga gccccaggac ctgcttttca aaagacttct 3950

 gcctgaccag agctcccact acatgcagtg gcccagggca gaggggctga 4000

 tacatggcct ttttcagggg gtgctcctcg cggggtggac ttgggagtgt 4050

 gcagtgggac agggggctgc aggggtcctg ccaccaccga gcaccaactt 4100

 ggcccctggg gtcctgcccc atgaatgagg ccttccccag ggctggcctg 4150

 actgtgctgg gggctgggtt aacgttttct cagggaacca caatgcacga 4200

 aagaggaact ggggttgcta accaggatgc tgggaacaaa ggcctcttga 4250

 agcccagcca cagcccagct gagcatgagg cccagcccat agacggcaca 4300

 ggccacctgg cccattccct gggcattccc tgctttgcat tgctgcttct 4350

 cttcacccca tggaggctat gtcaccctaa ctatcctgga atgtgttgag 4400

 agggattctg aatgatcaat atagcttggt gagacagtgc cgagatagat 4450

 agccatgtct gccttgggca cgggagaggg aagtggcagc atgcatgctg 4500

 tttcttggcc ttttctgtta gaatacttgg tgctttccaa cacactttca 4550

 catgtgttgt aacttgtttg atccaccccc ttccctgaaa atcctgggag 4600

 gttttattgc tgccatttaa cacagagggc aatagaggtt ctgaaaggtc 4650

 tgtgtcttgt caaaacaagt aaacggtgga actacgact 4689

<210> 5247
<211> 330
<212> PRT
<213> Homo sapien

<400> 5247
 Gly Arg Val Pro Pro Ala Pro Arg His Gln Lys Phe Leu Cys Ala
   1               5                  10                  15

 Ser Asp Gly Asp Met Gly Val Pro Thr Ala Leu Glu Ala Gly Ser
                  20                  25                  30

 Trp Arg Trp Gly Ser Leu Leu Phe Ala Leu Phe Leu Ala Ala Ser
                  35                  40                  45

 Leu Gly Pro Val Ala Ala Phe Lys Val Ala Thr Pro Tyr Ser Leu
                  50                  55                  60

 Tyr Val Cys Pro Glu Gly Gln Asn Val Thr Leu Thr Cys Arg Leu
                  65                  70                  75

 Leu Gly Pro Val Asp Lys Gly His Asp Val Thr Phe Tyr Lys Thr
                  80                  85                  90

 Trp Tyr Arg Ser Ser Arg Gly Glu Val Gln Thr Cys Ser Glu Arg
                  95                 100                 105

 Arg Pro Ile Arg Asn Leu Thr Phe Gln Asp Leu His Leu His His
                 110                 115                 120

 Gly Gly His Gln Ala Ala Asn Thr Ser His Asp Leu Ala Gln Arg
                 125                 130                 135

 His Gly Leu Glu Ser Ala Ser Asp His His Gly Asn Phe Ser Ile
                 140                 145                 150

 Thr Met Arg Asn Leu Thr Leu Leu Asp Ser Gly Leu Tyr Cys Cys
                 155                 160                 165

 Leu Val Val Glu Ile Arg His His His Ser Glu His Arg Val His
                 170                 175                 180

 Gly Ala Met Glu Leu Gln Val Gln Thr Gly Lys Asp Ala Pro Ser
                 185                 190                 195

 Asn Cys Val Val Tyr Pro Ser Ser Ser Gln Glu Ser Glu Asn Ile
                 200                 205                 210

 Thr Ala Ala Ala Leu Ala Thr Gly Ala Cys Ile Val Gly Ile Leu
                 215                 220                 225

 Cys Leu Pro Leu Ile Leu Leu Leu Val Tyr Lys Gln Arg Gln Ala
                 230                 235                 240

 Ala Ser Asn Arg Arg Ala Gln Glu Leu Val Arg Met Asp Ser Asn
                 245                 250                 255

 Ile Gln Gly Ile Glu Asn Pro Gly Phe Glu Ala Ser Pro Pro Ala
                 260                 265                 270

 Gln Gly Ile Pro Glu Ala Lys Val Arg His Pro Leu Ser Tyr Val
                 275                 280                 285

 Ala Gln Arg Gln Pro Ser Glu Ser Gly Arg His Leu Leu Ser Glu
                 290                 295                 300

 Pro Ser Thr Pro Leu Ser Pro Pro Gly Pro Gly Asp Val Phe Phe
                 305                 310                 315

 Pro Ser Leu Asp Pro Val Pro Asp Ser Pro Asn Phe Glu Val Ile
                 320                 325                 330

<210> 5248
<211> 3338
<212> DNA
<213> Homo sapien

<400> 5248
 cccagcccgg ccccgccgcc ccggctgcgc acgcgacgcc ccctccaggc 50

 cccgctcctg cgccctattt ggtcattcgg ggggcaagcg gcgggagggg 100

 aaacgtgcgc ggccgaaggg gaagcggagc cggcgccggc tgcgcagagg 150

 agccgctctc gccgccgcca cctcggctgg gagcccacga ggctgccgca 200

 tcctgccctc ggaacaatgg gactcggcgc gcgaggtgct tgggccgcgc 250

 tgctcctggg gacgctgcag gtgctagcgc tgctgggggc cgcccatgaa 300

 agcgcagcca tggcggagac tctccaacat gtgccttctg accatacaaa 350

 tgaaacttcc aacagtactg tgaaaccacc aacttcagtt gcctcagact 400

 ccagtaatac aacggtcacc accatgaaac ctacagcggc atctaataca 450

 acaacaccag ggatggtctc aacaaatatg acttctacca ccttaaagtc 500

 tacacccaaa acaacaagtg tttcacagaa cacatctcag atatcaacat 550

 ccacaatgac cgtaacccac aatagttcag tgacatctgc tgcttcatca 600

 gtaacaatca caacaactat gcattctgaa gcaaagaaag gatcaaaatt 650

 tgatactggg agctttgttg gtggtattgt attaacgctg ggagttttat 700

 ctattcttta cattggatgc aaaatgtatt actcaagaag aggcattcgg 750

 tatcgaacca tagatgaaca tgatgccatc atttaaggaa atccatggac 800

 caaggatgga atacagattg atgctgccct atcaattaat tttggtttat 850

 taatagttta aaacaatatt ctctttttga aaatagtata aacaggccat 900

 gcatataatg tacagtgtat tacgtaaata tgtaaagatt cttcaaggta 950

 acaagggttt gggttttgaa ataaacatct ggatcttata gaccgttcat 1000

 acaatggttt tagcaagttc atagtaagac aaacaagtcc tatctttttt 1050

 tttttggctg gggtgggggc attggtcaca tatgaccagt aattgaaaga 1100

 cgtcatcact gaaagacaga atgccatctg ggcatacaaa taagaagttt 1150

 gtcacagcac tcaggatttt gggtatcttt tgtagctcac ataaagaact 1200

 tcagtgcttt tcagagctgg atatatctta attactaatg ccacacagaa 1250

 attatacaat caaactagat ctgaagcata atttaagaaa aacatcaaca 1300

 ttttttgtgc tttaaactgt agtagttggt ctagaaacaa aatactccaa 1350

 gaaaaagaaa attttcaaat aaaacccaaa ataatagctt tgcttagccc 1400

 tgttagggat ccattggagc attaaggagc acatattttt attaacttct 1450

 tttgagcttt caatgttgat gtaatttttg ttctctgtgt aatttaggta 1500

 aactgcagtg tttaacataa taatgtttta aagacttagt tgtcagtatt 1550

 aaataatcct ggcattatag ggaaaaaacc tcctagaagt tagattattt 1600

 gctactgtga gaatattgtc accactggaa gttactttag ttcatttaat 1650

 tttaatttta tattttgtga atattttaag aactgtagag ctgctttcaa 1700

 tatctagaaa tttttaattg agtgtaaaca cacctaactt taagaaaaag 1750

 aaccgcttgt atgattttca aaagaacatt tagaattcta tagagtcaaa 1800

 actatagcgt aatgctgtgt ttattaagcc agggattgtg ggacttcccc 1850

 caggcaacta aacctgcagg atgaaaatgc tatattttct ttcatgcact 1900

 gtcgatatta ctcagatttg gggaaatgac atttttatac taaaacaaac 1950

 accaaaatat tttagaataa attcttagaa agttttgaga ggaattttta 2000

 gagaggacat ttcctccttc ctgatttgga tattccctca aatccctcct 2050

 cttactccat gctgaaggag aagtactctc agatgcatta tgttaatgga 2100

 gagaaaaagc acagtattgt agagacacca atattagcta atgtattttg 2150

 gagtgttttc cattttacag tttatattcc agcactcaaa actcagggtc 2200

 aagttttaac aaaagaggta tgtagtcaca gtaaatacta agatggcatt 2250

 tctatctcag agggccaaag tgaatcacac cagtttctga aggtcctaaa 2300

 aatagctcag atgtcctaat gaacatgcac ctacatttaa taggagtaca 2350

 ataaaactgt tgtcagcttt tgttttacag agaacgctag atattaagaa 2400

 ttttgaaatg gatcatttct acttgctgtg cattttaacc aataatctga 2450

 tgaatataga aaaaaatgat ccaaaatatg gatatgattg gatgtatgta 2500

 acacatacat ggagtatgga ggaaattttc tgaaaaatac atttagatta 2550

 gtttagtttg aaggagaggt gggctgatgg ctgagttgta tgttactaac 2600

 ttggccctga ctggttgtgc aaccattgct tcatttcttt gcaaaatgta 2650

 gttaagatat actttattct aatgaaggcc ttttaaattt gtccactgca 2700

 ttcttggtat ttcactactt caagtcagtc agaacttcgt agaccgacct 2750

 gaagtttctt tttgaatact tgtttcttta gcactttgaa gatagaaaaa 2800

 ccacttttta agtactaagt catcatttgc cttgaaagtt tcctctgcat 2850

 tgggtttgaa gtagtttagt tatgtctttt tctctgtatg taagtagtat 2900

 aatttgttac tttcaaatac ccgtactttg aatgtaggtt tttttgttgt 2950

 tgttatctat aaaaattgag ggaaatggtt atgcaaaaaa atattttgct 3000

 ttggaccata tttcttaagc ataaaaaaat gctcagtttt gcttgcattc 3050

 cttgagaatg tatttatctg aagatcaaaa caaacaatcc agatgtataa 3100

 gtactaggca gaagccaatt ttaaaatttc cttgaataat ccatgaaagg 3150

 aataattcaa atacagataa acagagttgg cagtatatta tagtgataat 3200

 tttgtatttt caamaaaaaa aaagttaaac tcttcttttc tttttattat 3250

 aatgaccagc ttttggtatt tcattgttac caagttctat ttttagataa 3300

 aattgttctc cttctaaaaa aaaaaaaaaa aaaaaaaa 3338

<210> 5249
<211> 189
<212> PRT
<213> Homo sapien

<400> 5249
 Met Gly Leu Gly Ala Arg Gly Ala Trp Ala Ala Leu Leu Leu Gly
   1               5                  10                  15

 Thr Leu Gln Val Leu Ala Leu Leu Gly Ala Ala His Glu Ser Ala
                  20                  25                  30

 Ala Met Ala Glu Thr Leu Gln His Val Pro Ser Asp His Thr Asn
                  35                  40                  45

 Glu Thr Ser Asn Ser Thr Val Lys Pro Pro Thr Ser Val Ala Ser
                  50                  55                  60

 Asp Ser Ser Asn Thr Thr Val Thr Thr Met Lys Pro Thr Ala Ala
                  65                  70                  75

 Ser Asn Thr Thr Thr Pro Gly Met Val Ser Thr Asn Met Thr Ser
                  80                  85                  90

 Thr Thr Leu Lys Ser Thr Pro Lys Thr Thr Ser Val Ser Gln Asn
                  95                 100                 105

 Thr Ser Gln Ile Ser Thr Ser Thr Met Thr Val Thr His Asn Ser
                 110                 115                 120

 Ser Val Thr Ser Ala Ala Ser Ser Val Thr Ile Thr Thr Thr Met
                 125                 130                 135

 His Ser Glu Ala Lys Lys Gly Ser Lys Phe Asp Thr Gly Ser Phe
                 140                 145                 150

 Val Gly Gly Ile Val Leu Thr Leu Gly Val Leu Ser Ile Leu Tyr
                 155                 160                 165

 Ile Gly Cys Lys Met Tyr Tyr Ser Arg Arg Gly Ile Arg Tyr Arg
                 170                 175                 180

 Thr Ile Asp Glu His Asp Ala Ile Ile
                 185

<210> 5250
<211> 1835
<212> DNA
<213> Homo sapien

<400> 5250
 gtgcagttgc ggctccaggg ccatggcgga ggagcagggc cgggaacggg 50

 actcggttcc caagccgtcg gtgctgttcc tccacccaga cctgggcgtg 100

 ggcggcgctg agcggctggt gttggacgcg gcgctggcgc tgcaggcgcg 150

 cgggtgtagc gtgaagatct ggacagcgca ctacgacccg ggccactgtt 200

 tcgccgagag ccgcgagcta ccggtgcgct gtgccgggga ctggctgccg 250

 cgaggcctgg gctggggcgg ccgcggcgcc gccgtctgcg cctacgtgcg 300

 catggttttc ctggcgctct acgtgctgtt cctcgccgac gaggagttcg 350

 acgtggtagt gtgcgaccag gtgtctgcct gtatcccagt gttcaggctg 400

 gctagacggc ggaagaagat cctattttac tgtcacttcc cagatctgct 450

 tctcaccaag agagattctt ttcttaaacg actatacagg gccccaattg 500

 actggataga ggaatacacc acaggcatgg cagactgcat cttagtcaac 550

 agccagttca cagctgctgt ttttaaggaa acattcaagt ccctgtctca 600

 catagaccct gatgtcctct atccatctct aaatgtcacc agctttgact 650

 cagttgttcc tgaaaagctg gatgacctag tccccaaggg gaaaaaattc 700

 ctgctgctct ccatcaacag atacgaaagg aagaaaaatc tgactttggc 750

 actggaagcc ctagtacagc tgcgtggaag attgacatcc caagattggg 800

 agagggttca tctgatcgtg gcaggtggtt atgacgagag agtcctggag 850

 aatgtggaac attatcagga attgaagaaa atggtccaac agtccgacct 900

 tggccagtat gtgaccttct tgaggtcttt ctcagacaaa cagaaaatct 950

 ccctcctcca cagctgcacg tgtgtgcttt acacaccaag caatgagcac 1000

 tttggcattg tccctctgga agccatgtac atgcagtgcc cagtcattgc 1050

 tgttaattcg ggtggaccct tggagtccat tgaccacagt gtcacagggt 1100

 ttctgtgtga gcctgacccg gtgcacttct cagaagcaat agaaaagttc 1150

 atccgtgaac cttccttaaa agccaccatg ggcctggctg gaagagccag 1200

 agtgaaggaa aaattttccc ctgaagcatt tacagaacag ctctaccgat 1250

 atgttaccaa actgctggta taatcagatt gtttttaaga tctccattaa 1300

 tgtcattttt atggattgta gacccagttt tgaaaccaaa aaagaaacct 1350

 agaatctaat gcagaagaga tcttttaaaa aataaacttg agtcttgaat 1400

 gtgagccact ttcctatata ccacacctcc ctgtccactt ttcagaaaaa 1450

 ccatgtcttt tatgctataa tcattccaaa ttttgccagt gttaagttac 1500

 aaatgtggtg tcattccatg ttcagcagag tattttaatt atattttctc 1550

 gggattattg ctcttctgtc tataaatttt gaatgatact gtgccttaat 1600

 tggttttcat agtttaagtg tgtatcatta tcaaagttga ttaatttggc 1650

 ttcatagtat aatgagagca gggctattgt agttcccaga ttcaatccac 1700

 cgaagtgttc actgtcatct gttagggaat ttttgtttgt cctgtctttg 1750

 cctggatcca tagcgagagt gctctgtatt ttttttaaga taatttgtat 1800

 ttttgcacac tgagatataa taaaaggtgt ttatc 1835

<210> 5251
<211> 416
<212> PRT
<213> Homo sapien

<400> 5251
 Met Ala Glu Glu Gln Gly Arg Glu Arg Asp Ser Val Pro Lys Pro
   1               5                  10                  15

 Ser Val Leu Phe Leu His Pro Asp Leu Gly Val Gly Gly Ala Glu
                  20                  25                  30

 Arg Leu Val Leu Asp Ala Ala Leu Ala Leu Gln Ala Arg Gly Cys
                  35                  40                  45

 Ser Val Lys Ile Trp Thr Ala His Tyr Asp Pro Gly His Cys Phe
                  50                  55                  60

 Ala Glu Ser Arg Glu Leu Pro Val Arg Cys Ala Gly Asp Trp Leu
                  65                  70                  75

 Pro Arg Gly Leu Gly Trp Gly Gly Arg Gly Ala Ala Val Cys Ala
                  80                  85                  90

 Tyr Val Arg Met Val Phe Leu Ala Leu Tyr Val Leu Phe Leu Ala
                  95                 100                 105

 Asp Glu Glu Phe Asp Val Val Val Cys Asp Gln Val Ser Ala Cys
                 110                 115                 120

 Ile Pro Val Phe Arg Leu Ala Arg Arg Arg Lys Lys Ile Leu Phe
                 125                 130                 135

 Tyr Cys His Phe Pro Asp Leu Leu Leu Thr Lys Arg Asp Ser Phe
                 140                 145                 150

 Leu Lys Arg Leu Tyr Arg Ala Pro Ile Asp Trp Ile Glu Glu Tyr
                 155                 160                 165

 Thr Thr Gly Met Ala Asp Cys Ile Leu Val Asn Ser Gln Phe Thr
                 170                 175                 180

 Ala Ala Val Phe Lys Glu Thr Phe Lys Ser Leu Ser His Ile Asp
                 185                 190                 195

 Pro Asp Val Leu Tyr Pro Ser Leu Asn Val Thr Ser Phe Asp Ser
                 200                 205                 210

 Val Val Pro Glu Lys Leu Asp Asp Leu Val Pro Lys Gly Lys Lys
                 215                 220                 225

 Phe Leu Leu Leu Ser Ile Asn Arg Tyr Glu Arg Lys Lys Asn Leu
                 230                 235                 240

 Thr Leu Ala Leu Glu Ala Leu Val Gln Leu Arg Gly Arg Leu Thr
                 245                 250                 255

 Ser Gln Asp Trp Glu Arg Val His Leu Ile Val Ala Gly Gly Tyr
                 260                 265                 270

 Asp Glu Arg Val Leu Glu Asn Val Glu His Tyr Gln Glu Leu Lys
                 275                 280                 285

 Lys Met Val Gln Gln Ser Asp Leu Gly Gln Tyr Val Thr Phe Leu
                 290                 295                 300

 Arg Ser Phe Ser Asp Lys Gln Lys Ile Ser Leu Leu His Ser Cys
                 305                 310                 315

 Thr Cys Val Leu Tyr Thr Pro Ser Asn Glu His Phe Gly Ile Val
                 320                 325                 330

 Pro Leu Glu Ala Met Tyr Met Gln Cys Pro Val Ile Ala Val Asn
                 335                 340                 345

 Ser Gly Gly Pro Leu Glu Ser Ile Asp His Ser Val Thr Gly Phe
                 350                 355                 360

 Leu Cys Glu Pro Asp Pro Val His Phe Ser Glu Ala Ile Glu Lys
                 365                 370                 375

 Phe Ile Arg Glu Pro Ser Leu Lys Ala Thr Met Gly Leu Ala Gly
                 380                 385                 390

 Arg Ala Arg Val Lys Glu Lys Phe Ser Pro Glu Ala Phe Thr Glu
                 395                 400                 405

 Gln Leu Tyr Arg Tyr Val Thr Lys Leu Leu Val
                 410                 415

<210> 5252
<211> 1959
<212> DNA
<213> Homo sapien

<400> 5252
 atcacttggc tcttctctga tatgaactgg gcagcatcta aatgtatctt 50

 tcttgatttt gttgtctctt tgcatagagc atatcttgtg aaaacagaaa 100

 tatccatgta atggtttttt cttgtagtga ccgctcgaaa ttgcttgagc 150

 aacatagaga taatgggcag gggtccctgt gtgaagcacc tagaggctgg 200

 aaagctgatg gcaaagctgg aggggtgagg cagggagagg ataaacacag 250

 tggaaatgca ggaggaaagc tgtgctctgt ggtggcctaa ttacaaggac 300

 ctgccctaca gccagaatca gccagcaaat gcttttgtaa aggaactaaa 350

 agaaagggaa aagaggaagt aaacaaaagg tcccttttca gagagggaac 400

 cagtgggaga cttaagagca aggaacaacc catttcgtcg ttatggtaag 450

 tggagattat tccttgggcc tgaatgactt gaatgtttcc ccgcctgagc 500

 taacagtcca tgtgggtgat tcagctctga tgggatgtgt tttccagagc 550

 acagaagaca aatgtatatt caagatagac tggactctgt caccaggaga 600

 gcacgccaag gacgaatatg tgctatacta ttactccaat ctcagtgtgc 650

 ctattgggcg cttccagaac cgcgtacact tgatggggga caacttatgc 700

 aatgatggct ctctcctgct ccaagatgtg caagaggctg accagggaac 750

 ctatatctgt gaaatccgcc tcaaagggga gagccaggtg ttcaagaagg 800

 cggtggtact gcatgtgctt ccagaggagc ccaaagagct catggtccat 850

 gtgggtggat tgattcagat gggatgtgtt ttccagagca cagaagtgaa 900

 acacgtgacc aaggtagaat ggatattttc aggacggcgc gcaaaggagg 950

 agattgtatt tcgttactac cacaaactca ggatgtctgc ggagtactcc 1000

 cagagctggg gccacttcca gaatcgtgtg aacctggtgg gggacatttt 1050

 ccgcaatgac ggttccatca tgcttcaagg agtgagggag tcagatggag 1100

 gaaactacac ctgcagtatc cacctaggga acctggtgtt caagaaaacc 1150

 attgtgctgc atgtcagccc ggaagagcct cgaacactgg tgaccccggc 1200

 agccctgagg cctctggtct tgggtggtaa tcagttggtg atcattgtgg 1250

 gaattgtctg tgccacaatc ctgctgctcc ctgttctgat attgatcgtg 1300

 aagaagacct gtggaaataa gagttcagtg aattctacag tcttggtgaa 1350

 gaacacgaag aagactaatc cagagataaa agaaaaaccc tgccattttg 1400

 aaagatgtga aggggagaaa cacatttact ccccaataat tgtacgggag 1450

 gtgatcgagg aagaagaacc aagtgaaaaa tcagaggcca cctacatgac 1500

 catgcaccca gtttggcctt ctctgaggtc agatcggaac aactcacttg 1550

 aaaaaaagtc aggtggggga atgccaaaaa cacagcaagc cttttgagaa 1600

 gaatggagag tcccttcatc tcagcagcgg tggagactct ctcctgtgtg 1650

 tgtcctgggc cactctacca gtgatttcag actcccgctc tcccagctgt 1700

 cctcctgtct cattgtttgg tcaatacact gaagatggag aatttggagc 1750

 ctggcagaga gactggacag ctctggagga acaggcctgc tgaggggagg 1800

 ggagcatgga cttggcctct ggagtgggac actggccctg ggaaccaggc 1850

 tgagctgagt ggcctcaaac cccccgttgg atcagaccct cctgtgggca 1900

 gggttcttag tggatgagtt actgggaaga atcagagata aaaaccaacc 1950

 caaatcatt 1959

<210> 5253
<211> 384
<212> PRT
<213> Homo sapien

<400> 5253
 Met Val Ser Gly Asp Tyr Ser Leu Gly Leu Asn Asp Leu Asn Val
   1               5                  10                  15

 Ser Pro Pro Glu Leu Thr Val His Val Gly Asp Ser Ala Leu Met
                  20                  25                  30

 Gly Cys Val Phe Gln Ser Thr Glu Asp Lys Cys Ile Phe Lys Ile
                  35                  40                  45

 Asp Trp Thr Leu Ser Pro Gly Glu His Ala Lys Asp Glu Tyr Val
                  50                  55                  60

 Leu Tyr Tyr Tyr Ser Asn Leu Ser Val Pro Ile Gly Arg Phe Gln
                  65                  70                  75

 Asn Arg Val His Leu Met Gly Asp Asn Leu Cys Asn Asp Gly Ser
                  80                  85                  90

 Leu Leu Leu Gln Asp Val Gln Glu Ala Asp Gln Gly Thr Tyr Ile
                  95                 100                 105

 Cys Glu Ile Arg Leu Lys Gly Glu Ser Gln Val Phe Lys Lys Ala
                 110                 115                 120

 Val Val Leu His Val Leu Pro Glu Glu Pro Lys Glu Leu Met Val
                 125                 130                 135

 His Val Gly Gly Leu Ile Gln Met Gly Cys Val Phe Gln Ser Thr
                 140                 145                 150

 Glu Val Lys His Val Thr Lys Val Glu Trp Ile Phe Ser Gly Arg
                 155                 160                 165

 Arg Ala Lys Glu Glu Ile Val Phe Arg Tyr Tyr His Lys Leu Arg
                 170                 175                 180

 Met Ser Ala Glu Tyr Ser Gln Ser Trp Gly His Phe Gln Asn Arg
                 185                 190                 195

 Val Asn Leu Val Gly Asp Ile Phe Arg Asn Asp Gly Ser Ile Met
                 200                 205                 210

 Leu Gln Gly Val Arg Glu Ser Asp Gly Gly Asn Tyr Thr Cys Ser
                 215                 220                 225

 Ile His Leu Gly Asn Leu Val Phe Lys Lys Thr Ile Val Leu His
                 230                 235                 240

 Val Ser Pro Glu Glu Pro Arg Thr Leu Val Thr Pro Ala Ala Leu
                 245                 250                 255

 Arg Pro Leu Val Leu Gly Gly Asn Gln Leu Val Ile Ile Val Gly
                 260                 265                 270

 Ile Val Cys Ala Thr Ile Leu Leu Leu Pro Val Leu Ile Leu Ile
                 275                 280                 285

 Val Lys Lys Thr Cys Gly Asn Lys Ser Ser Val Asn Ser Thr Val
                 290                 295                 300

 Leu Val Lys Asn Thr Lys Lys Thr Asn Pro Glu Ile Lys Glu Lys
                 305                 310                 315

 Pro Cys His Phe Glu Arg Cys Glu Gly Glu Lys His Ile Tyr Ser
                 320                 325                 330

 Pro Ile Ile Val Arg Glu Val Ile Glu Glu Glu Glu Pro Ser Glu
                 335                 340                 345

 Lys Ser Glu Ala Thr Tyr Met Thr Met His Pro Val Trp Pro Ser
                 350                 355                 360

 Leu Arg Ser Asp Arg Asn Asn Ser Leu Glu Lys Lys Ser Gly Gly
                 365                 370                 375

 Gly Met Pro Lys Thr Gln Gln Ala Phe
                 380

<210> 5254
<211> 1388
<212> DNA
<213> Homo sapien

<400> 5254
 gtgcgtgagt ttggtggcgg ccggctgtgc agagacgcca tgtaccggct 50

 catgtcagca gtgactgccc gggctgccgc ccccgggggc ttggcctcaa 100

 gctgcggacg acgcggggtc catcagcgcg ccgggctgcc gcctctcggc 150

 cacggctggg tcgggggcct cgggctgggg ctggggctgg cgctcggggt 200

 gaagctggca ggtgggctga ggggcgcggc cccggcgcag tcccccgcgg 250

 cccccgaccc tgaggcgtcg cctctggccg agccgccaca ggagcagtcc 300

 ctcgccccgt ggtctccgca gaccccggcg ccgccctgct ccaggtgctt 350

 cgccagagcc atcgagagca gccgcgacct gctgcacagg atcaaggatg 400

 aggtgggcgc accgggcata gtggttggag tttctgtaga tggaaaagaa 450

 gtctggtcag aaggtttagg ttatgctgat gttgagaacc gtgtaccatg 500

 taaaccagag acagttatgc gaattgctag catcagcaaa agtctcacca 550

 tggttgctct tgccaaattg tgggaagcag ggaaactgga tcttgatatt 600

 ccagtacaac attatgttcc cgaattccca gaaaaagaat atgaaggtga 650

 aaaggtttct gtcacaacaa gattactgat ttcccattta agtggaattc 700

 gtcattatga aaaggacata aaaaaggtga aagaagagaa agcttataaa 750

 gccttgaaga tgatgaaaga gaatgttgca tttgagcaag aaaaagaagg 800

 caaaagtaat gaaaagaatg attttactaa atttaaaaca gagcaggaga 850

 atgaagccaa atgccggaat tcaaaacctg gcaagaaaaa gaatgatttt 900

 gaacaaggcg aattatattt gagagaaaag tttgaaaatt caattgaatc 950

 cctaagatta tttaaaaatg atcctttgtt cttcaaacct ggtagtcagt 1000

 ttttgtattc aacttttggc tataccctac tggcagccat agtagagaga 1050

 gcttcaggat gtaaatattt ggactatatg cagaaaatat tccatgactt 1100

 ggatatgctg acgactgtgc aggaagaaaa cgagccagtg atttacaata 1150

 gagcaaggta aatgaatacc ttctgctgtg tctagctata tcgcatctta 1200

 acactatttt attaattaaa agtcaaattt tctttgtttc cattccaaaa 1250

 tcaacctgcc acattttggg agcttttcta catgtctgtt ttctcatctg 1300

 taaagtgaag gaagtaaaac atgtttataa agtaaaaaaa aaaaaaaaaa 1350

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1388

<210> 5255
<211> 373
<212> PRT
<213> Homo sapien

<400> 5255
 Met Tyr Arg Leu Met Ser Ala Val Thr Ala Arg Ala Ala Ala Pro
   1               5                  10                  15

 Gly Gly Leu Ala Ser Ser Cys Gly Arg Arg Gly Val His Gln Arg
                  20                  25                  30

 Ala Gly Leu Pro Pro Leu Gly His Gly Trp Val Gly Gly Leu Gly
                  35                  40                  45

 Leu Gly Leu Gly Leu Ala Leu Gly Val Lys Leu Ala Gly Gly Leu
                  50                  55                  60

 Arg Gly Ala Ala Pro Ala Gln Ser Pro Ala Ala Pro Asp Pro Glu
                  65                  70                  75

 Ala Ser Pro Leu Ala Glu Pro Pro Gln Glu Gln Ser Leu Ala Pro
                  80                  85                  90

 Trp Ser Pro Gln Thr Pro Ala Pro Pro Cys Ser Arg Cys Phe Ala
                  95                 100                 105

 Arg Ala Ile Glu Ser Ser Arg Asp Leu Leu His Arg Ile Lys Asp
                 110                 115                 120

 Glu Val Gly Ala Pro Gly Ile Val Val Gly Val Ser Val Asp Gly
                 125                 130                 135

 Lys Glu Val Trp Ser Glu Gly Leu Gly Tyr Ala Asp Val Glu Asn
                 140                 145                 150

 Arg Val Pro Cys Lys Pro Glu Thr Val Met Arg Ile Ala Ser Ile
                 155                 160                 165

 Ser Lys Ser Leu Thr Met Val Ala Leu Ala Lys Leu Trp Glu Ala
                 170                 175                 180

 Gly Lys Leu Asp Leu Asp Ile Pro Val Gln His Tyr Val Pro Glu
                 185                 190                 195

 Phe Pro Glu Lys Glu Tyr Glu Gly Glu Lys Val Ser Val Thr Thr
                 200                 205                 210

 Arg Leu Leu Ile Ser His Leu Ser Gly Ile Arg His Tyr Glu Lys
                 215                 220                 225

 Asp Ile Lys Lys Val Lys Glu Glu Lys Ala Tyr Lys Ala Leu Lys
                 230                 235                 240

 Met Met Lys Glu Asn Val Ala Phe Glu Gln Glu Lys Glu Gly Lys
                 245                 250                 255

 Ser Asn Glu Lys Asn Asp Phe Thr Lys Phe Lys Thr Glu Gln Glu
                 260                 265                 270

 Asn Glu Ala Lys Cys Arg Asn Ser Lys Pro Gly Lys Lys Lys Asn
                 275                 280                 285

 Asp Phe Glu Gln Gly Glu Leu Tyr Leu Arg Glu Lys Phe Glu Asn
                 290                 295                 300

 Ser Ile Glu Ser Leu Arg Leu Phe Lys Asn Asp Pro Leu Phe Phe
                 305                 310                 315

 Lys Pro Gly Ser Gln Phe Leu Tyr Ser Thr Phe Gly Tyr Thr Leu
                 320                 325                 330

 Leu Ala Ala Ile Val Glu Arg Ala Ser Gly Cys Lys Tyr Leu Asp
                 335                 340                 345

 Tyr Met Gln Lys Ile Phe His Asp Leu Asp Met Leu Thr Thr Val
                 350                 355                 360

 Gln Glu Glu Asn Glu Pro Val Ile Tyr Asn Arg Ala Arg
                 365                 370

<210> 5256
<211> 7734
<212> DNA
<213> Homo sapien

<400> 5256
 agaggctgcg gtgagtccgc cagccccagc tgctcctcct caagccccca 50

 aggcccttcg gcgggcccct gctgaaagac cggcatgccc tattctgtgg 100

 gcttccgcga agccgatgct gctaccagct ttctgagagc agcaagatca 150

 ggtaacttgg acaaagcttt ggatcacctg cggaatgggg tagatattaa 200

 cacctgtaac cagaatgggt tgaatggctt gcatctggct tctaaggaag 250

 gccatgtgaa aatggtggtt gaacttctgc acaaagaaat cattctagaa 300

 acgacaacca agaaggggaa cacggccctg cacatcgctg ctctagccgg 350

 gcaggatgag gtggtccggg agcttgtcaa ctatggagcc aacgtcaatg 400

 cccagtcaca gaaaggtttt acacccctgt acatggcagc acaagagaac 450

 cacttggaag tggttaagtt tttactggaa aatggagcta accagaatgt 500

 agccacagaa gacggcttca cgcctctggc ggtagccctg cagcagggcc 550

 atgagaacgt cgtcgcgcac ctcatcaact acggcaccaa ggggaaggtg 600

 cgcctcccgg ccctgcacat cgcggcccgc aacgacgaca cgcgcacggc 650

 tgcggtgctg ctgcagaacg accccaaccc ggacgtgctt tccaagacgg 700

 gattcacgcc cctgcacatt gcggctcact acgagaacct caacgtggcc 750

 cagttgctcc tcaacagagg agccagcgtc aatttcacac cacagaacgg 800

 catcacgcca ctgcacatcg cctcccgcag gggcaacgtg atcatggtgc 850

 ggctgctgct ggatcgggga gcccagatag aaaccaagac caaggacgaa 900

 ttgacacctc tccactgtgc agctcgaaat gggcacgtgc gaatctcaga 950

 gatcctgctg gaccacgggg caccaatcca agccaaaacc aagaacggcc 1000

 tgtccccaat tcacatggcg gctcagggag accacctcga ctgtgtccgg 1050

 ctcctgttgc aatacgacgc agagatagac gacatcaccc tggaccacct 1100

 gaccccactc cacgtggctg cccactgtgg acaccacagg gtggctaagg 1150

 tccttctgga taaaggggcc aaacccaact ccagagccct gaatggcttt 1200

 acccccttac acatcgcctg caaaaagaac cacgtccgtg tcatggagct 1250

 gctgctgaag acgggagcct cgatcgacgc ggtcaccgag tctggcctga 1300

 cacctctcca cgtggcctcc ttcatggggc accttcccat cgtgaagaac 1350

 ctcctgcagc ggggggcgtc gcccaacgtc tccaacgtga aagtggagac 1400

 cccgctacac atggcagcca gagccgggca cacggaagtg gccaaatatt 1450

 tactccagaa caaagccaaa gtcaatgcca aggccaagga tgaccagacc 1500

 ccacttcact gtgcagctcg catcggccac acaaacatgg tgaagctcct 1550

 gctggaaaat aacgccaacc ccaacctggc caccaccgcc gggcacaccc 1600

 ccctgcacat tgcagcccgt gagggccatg tggaaacagt cctggccctt 1650

 ctggaaaagg aagcatccca ggcctgcatg accaagaaag gatttacccc 1700

 tctgcacgtg gcggccaagt acgggaaggt gcgggtggca gagctgctgc 1750

 tggagcggga cgcacacccg aatgctgccg gaaaaaatgg cctgaccccc 1800

 ctgcacgtgg ccgtccatca caacaacctg gacatcgtca agctgctgct 1850

 tccccggggc ggctccccgc acagccctgc ctggaatggc tacacccctt 1900

 tgcacatcgc tgccaagcag aaccaggtgg aggtggcccg tagtctgctg 1950

 cagtatgggg gctcagcaaa cgccgagtcg gtgcaaggtg tgacgcccct 2000

 tcacctggcc gcccaggagg gccacgcaga gatggtggct ctgctgctct 2050

 cgaaacaagc caatggcaac ctggggaaca agagcggact cactcccctc 2100

 catctggtag cacaagaagg ccacgttcca gtggcagatg tgctgatcaa 2150

 acacggtgtc atggtggacg ccaccacccg gatgggctac actcccctcc 2200

 atgtggccag tcactatgga aacatcaagc tggtgaagtt tctgctgcag 2250

 caccaggcag atgtcaatgc caagaccaag ctaggataca gccccctgca 2300

 ccaggcagcc cagcagggac acacagacat cgtgactctg cttctgaaaa 2350

 acggtgcttc cccaaacgag gtcagctcgg atggaaccac acctctggcc 2400

 atagccaagc gcttgggcta catttctgtc accgacgtgc tcaaggtcgt 2450

 cacggatgaa accagtttcg tgttagtcag tgataagcat cgaatgagtt 2500

 tccctgagac agttgatgag atcctggatg tctcggaaga tgaaggggaa 2550

 gaactcatca gcttcaaggc tgagaggcgg gattccaggg atgttgatga 2600

 agagaaggag ctgctggatt ttgtgccgaa gctagaccaa gtggtggaat 2650

 ctccagccat ccccaggatt ccctgtgcca tgcctgagac agtggtgatc 2700

 aggtcagaag agcaggagca ggcatctaaa gagtatgatg aggactccct 2750

 catccccagc agcccggcca ccgagacctc agacaacatc agcccggtgg 2800

 ccagcccggt gcatacaggg tttctggtga gcttcatggt tgacgcccgg 2850

 ggtggttcca tgagaggaag tcgccacaac ggcctgcgag tggtgatccc 2900

 gccacggacg tgcgcagcgc ccacccgcat cacctgccgc ctggtcaagc 2950

 cccagaagct cagcacgccg cccccactgg ccgaggagga gggcctggcc 3000

 agcaggatca tagcactggg gcccacgggg gcacagttcc tgagccctgt 3050

 aatcgtggag atcccgcact ttgcctccca tggccgtgga gaccgcgagc 3100

 tcgtggttct gaggagcgaa aacggctccg tgtggaagga gcacaggagc 3150

 cgctatggag agagctacct ggatcagatc ctcaacggga tggacgaaga 3200

 gctggggagc ctggaggagc tagagaagaa gagggtgtgc cgaatcatca 3250

 ccaccgactt cccgctgtac ttcgtgatca tgtcacggct ctgccaggac 3300

 tacgacatca tcggtcccga agggggctcc ctgaagagca agctggtgcc 3350

 cctggtacag gcaacgttcc cggagaatgc cgtcaccaag agagtgaagc 3400

 tggctctgca ggcccagcct gtcccggatg agcttgtcac taagctcctg 3450

 ggcaaccagg ccacattcag ccccattgtc accgtggagc cccggcgccg 3500

 gaagttccac cgccccattg ggcttcggat cccactacct ccttcctgga 3550

 ccgacaaccc gagggacagt ggggagggag acaccaccag cctgcgcctg 3600

 ctttgcagcg tcattggagg aacagaccaa gcccagtggg aagacataac 3650

 aggaaccacc aaacttgtat atgccaacga gtgcgccaac ttcaccacca 3700

 atgtctctgc caggttttgg ctgtcggact gtcctcggac tgctgaggct 3750

 gtgaactttg ccaccctgct gtacaaagag ctcactgcag tgccctacat 3800

 ggccaaattc gtcatctttg ccaagatgaa tgacccccga gaggggcgcc 3850

 tgcgctgcta ctgcatgaca gatgataaag tggacaagac cctggagcag 3900

 catgagaact tcgtggaggt ggcccggagc agggacatag aggtgttgga 3950

 aggaatgtcc ctgtttgcag aactctctgg gaacctggtg cctgtgaaga 4000

 aagctgccca gcagcggagc ttccacttcc agtcatttcg ggagaaccgt 4050

 ctggccatgc ctgtaaaggt gagggacagc agtcgagagc cgggagggtc 4100

 cctgtcgttt ctgcgcaagg cgatgaagta cgaggacacc cagcacattc 4150

 tctgccacct gaacatcacc atgcccccct gcgctaaggg aagtggagcc 4200

 gaagatagga gaaggacccc gacgcccctg gccctgcgat acagcattct 4250

 cagtgagtcc acaccaggtt ctctcagtgg gacagagcag gcagagatga 4300

 agatggctgt tatctcagag cacctcggtc tcagctgggc agagttggcc 4350

 cgggagctgc agttcagtgt ggaagacatc aacaggatcc gagtggaaaa 4400

 tcccaactcc ctgttggagc agagtgtggc cttgctgaac ctctgggtca 4450

 tccgtgaagg ccaaaacgca aacatggaga atctgtacac agccctgcag 4500

 agcattgacc gtggcgagat cgtgaacatg ctggagggtt ccggccgaca 4550

 gagccgcaac ttgaagccag acaggcggca caccgaccgc gactactcgc 4600

 tgtcaccctc ccagatgaat ggccatcaga gggggcaagc ccgaatcaca 4650

 cattccccca ccgtgagtca ggtgacggag aggagtcagg acagactgca 4700

 ggactgggat gcagacggct cgattgtctc atacctgcaa gatgctgcac 4750

 aaggttcctg gcaagaggag gtcacgcaag gtccacactc attccaggga 4800

 acaagtacca tgactgaagg gctagagccc ggtggatctc aggagtacga 4850

 gaaggtcctg gtgtctgtaa gtgagcacac gtggacagaa cagcccgagg 4900

 ctgagagctc ccaggccgac agggaccgga ggcagcaagg ccaagaagag 4950

 caggtgcagg aggccaagaa caccttcacc caagtggtgc aggggaatga 5000

 gtttcagaat attccagggg agcaggtgac agaggagcaa ttcacggatg 5050

 agcagggcaa cattgtcacc aagaagatca ttcgcaaggt ggttcgacag 5100

 atagacttgt ccagcgccga tgccgcccag gagcacgagg aggtgactgt 5150

 agaggggccc ctggaggatc ccagtgagct ggaggtcgat attgattact 5200

 ttatgaaaca ctccaaggat cacacctcga cacccaaccc ctgaacccca 5250

 cacactctgc catgcacaca ggaggagagc tggacctgag ggccaccgca 5300

 gcggtgcaca cattcctctg ggctgacggc atgacctctg taagggactc 5350

 ctgctagtcc cctcttggca tgaatgactg actgtagacg catgacctcc 5400

 aggcttcaat cctgcctctt gcaatgacag ctgatctgtc ggaaccagga 5450

 cacaaaagca gcaagaagcg gggagagaga gggatagaaa acaagcgcag 5500

 gagagcctgc gaacgcaaaa gtgaatgagg gctttttgtg gctggggatg 5550

 ggttttggtt ttggggtttt ttttttaaat tgttttgact tcgtacaggg 5600

 tactttttcc caacctcatc tgtcagaaat ccatgtgggc ttcctggaaa 5650

 gaaaaaaaaa aaaaagaaaa ctaggcatga aatcagttta acaccttaat 5700

 cttaagccat gtcctcatct gcccaccctc cccaacccac atacctccat 5750

 tccacttgtg acaccccctc gactccctgg tgacgctcct cccagatcgc 5800

 tctacatgac attcaggaca cacacacaca cacacacaca cacaccactc 5850

 gcctccactg aatctacaca cagattttac tgtgacttct gaagctgtgg 5900

 ataaattgga attttttatg ttgtctctct ctctgccaat ttcaatacga 5950

 atcatcttcc aatggaaaat cattaccttg aagagtgcat tcggggttcc 6000

 ttgtgttagg gacttaagaa tctgaggcgc gaggaccccc aggcttacct 6050

 gtaggactca aagggagcca ggaccccatc tgaaagggtc tcctctctca 6100

 gttgggggac aggccggtgg ctgacccagg attgcaccag catgtccata 6150

 gagaagaggt tttctatgtc ttcaagcact atatcatagt ccgtgttcaa 6200

 agtgtaaact gtacagtaat cagccttgtg tatatgaaaa acaataaata 6250

 ctatgcaaac caatagaaac atttagcagt acgtacagag cctgacagcg 6300

 cagctcctga ggacttctgc ggctgcagga gaaggagctg tggcctgtct 6350

 ttcagtgaaa gaggaaggaa aggagtaggg ctagtgaatg tatctgccag 6400

 gtcttagaag tcaggaccac ccagggtctc ccagagtgaa cttggtgctc 6450

 taagtccagg cagcctgcag gctggggacc ctgggtgcag gtgccaggct 6500

 cgaggctgtt ccctgtcctg cctcagtgcc tcccctctgc ccagcccctg 6550

 tggcctcttg gagaggcgag ccagggggct ccccggaccg catggccggt 6600

 gagagtagag tcggaggcgg agagcctgga cgcccagagg ccggggccag 6650

 gctctgggtc aaggcaggaa ggagacagac agctggcagt tcctcgcctc 6700

 ggtgccatca gggaggagcc ttaagttcca ctagagcctc cggcccaggg 6750

 aggccagaat cagcacaatc ccggccccgc cctcgcggcg ggcgccccca 6800

 gggccaggag agagagacag ggctggctcc tctcgcccct ggagccgcgg 6850

 tgtggacggc ccggccccgt ccgccccgcc gctctgcggg agtgtccttc 6900

 gggacacact taaaccttcc aagtagcaca gaagccccct ccacgtcaga 6950

 gccccctggc cgcggggcct gtgagcggag aggggccctg cttcccacac 7000

 aaatccgccc cggtgcaccc ccggccaggc aggccccggg gcggcctagg 7050

 cgccttgtcg gccgggggtg gggctgcttt tgcttccttt agaggggcgg 7100

 gcagggagag gaagctctag ctccgggcct gagtttcccc gaggctgcgt 7150

 cggaggagct gcagggcgag cccggacggc tgccgtctcc gccagaggcc 7200

 accccggccc ggcctccagg cagaggcgcc cccctccatc ctcccccatc 7250

 ccgggggcca cggcaggggg gccgcacagc gcggctggga ccgattcggt 7300

 gacggcccaa ggaagctggg cgcagggctc gcctctcccg cctcgatcct 7350

 gcaccttcct ctcccaggtc gctgctgcag ccaacccagt agccccctta 7400

 gcgcccccgc ggaccccgca gctccagact ccgctttggc acctctgctc 7450

 cggctggcat ggctgcacgc tccggctgct agtaggagcc gttaggggag 7500

 gagtttgggg tctccacacg atgcctagag aatgctgcag tctgcacatt 7550

 agacgctttt tagaagtttt gaaattacct tgattttttt aattgttatg 7600

 aaaatggatc ttttcttgac tctcccacat gctctgttat gggagagaat 7650

 cccctaccct actctgatgt atagaccatt ctcccttcac cagccgaacc 7700

 aatgtcaaaa ttaataaaga aatggactaa ggca 7734

<210> 5257
<211> 1719
<212> PRT
<213> Homo sapien

<400> 5257
 Met Pro Tyr Ser Val Gly Phe Arg Glu Ala Asp Ala Ala Thr Ser
   1               5                  10                  15

 Phe Leu Arg Ala Ala Arg Ser Gly Asn Leu Asp Lys Ala Leu Asp
                  20                  25                  30

 His Leu Arg Asn Gly Val Asp Ile Asn Thr Cys Asn Gln Asn Gly
                  35                  40                  45

 Leu Asn Gly Leu His Leu Ala Ser Lys Glu Gly His Val Lys Met
                  50                  55                  60

 Val Val Glu Leu Leu His Lys Glu Ile Ile Leu Glu Thr Thr Thr
                  65                  70                  75

 Lys Lys Gly Asn Thr Ala Leu His Ile Ala Ala Leu Ala Gly Gln
                  80                  85                  90

 Asp Glu Val Val Arg Glu Leu Val Asn Tyr Gly Ala Asn Val Asn
                  95                 100                 105

 Ala Gln Ser Gln Lys Gly Phe Thr Pro Leu Tyr Met Ala Ala Gln
                 110                 115                 120

 Glu Asn His Leu Glu Val Val Lys Phe Leu Leu Glu Asn Gly Ala
                 125                 130                 135

 Asn Gln Asn Val Ala Thr Glu Asp Gly Phe Thr Pro Leu Ala Val
                 140                 145                 150

 Ala Leu Gln Gln Gly His Glu Asn Val Val Ala His Leu Ile Asn
                 155                 160                 165

 Tyr Gly Thr Lys Gly Lys Val Arg Leu Pro Ala Leu His Ile Ala
                 170                 175                 180

 Ala Arg Asn Asp Asp Thr Arg Thr Ala Ala Val Leu Leu Gln Asn
                 185                 190                 195

 Asp Pro Asn Pro Asp Val Leu Ser Lys Thr Gly Phe Thr Pro Leu
                 200                 205                 210

 His Ile Ala Ala His Tyr Glu Asn Leu Asn Val Ala Gln Leu Leu
                 215                 220                 225

 Leu Asn Arg Gly Ala Ser Val Asn Phe Thr Pro Gln Asn Gly Ile
                 230                 235                 240

 Thr Pro Leu His Ile Ala Ser Arg Arg Gly Asn Val Ile Met Val
                 245                 250                 255

 Arg Leu Leu Leu Asp Arg Gly Ala Gln Ile Glu Thr Lys Thr Lys
                 260                 265                 270

 Asp Glu Leu Thr Pro Leu His Cys Ala Ala Arg Asn Gly His Val
                 275                 280                 285

 Arg Ile Ser Glu Ile Leu Leu Asp His Gly Ala Pro Ile Gln Ala
                 290                 295                 300

 Lys Thr Lys Asn Gly Leu Ser Pro Ile His Met Ala Ala Gln Gly
                 305                 310                 315

 Asp His Leu Asp Cys Val Arg Leu Leu Leu Gln Tyr Asp Ala Glu
                 320                 325                 330

 Ile Asp Asp Ile Thr Leu Asp His Leu Thr Pro Leu His Val Ala
                 335                 340                 345

 Ala His Cys Gly His His Arg Val Ala Lys Val Leu Leu Asp Lys
                 350                 355                 360

 Gly Ala Lys Pro Asn Ser Arg Ala Leu Asn Gly Phe Thr Pro Leu
                 365                 370                 375

 His Ile Ala Cys Lys Lys Asn His Val Arg Val Met Glu Leu Leu
                 380                 385                 390

 Leu Lys Thr Gly Ala Ser Ile Asp Ala Val Thr Glu Ser Gly Leu
                 395                 400                 405

 Thr Pro Leu His Val Ala Ser Phe Met Gly His Leu Pro Ile Val
                 410                 415                 420

 Lys Asn Leu Leu Gln Arg Gly Ala Ser Pro Asn Val Ser Asn Val
                 425                 430                 435

 Lys Val Glu Thr Pro Leu His Met Ala Ala Arg Ala Gly His Thr
                 440                 445                 450

 Glu Val Ala Lys Tyr Leu Leu Gln Asn Lys Ala Lys Val Asn Ala
                 455                 460                 465

 Lys Ala Lys Asp Asp Gln Thr Pro Leu His Cys Ala Ala Arg Ile
                 470                 475                 480

 Gly His Thr Asn Met Val Lys Leu Leu Leu Glu Asn Asn Ala Asn
                 485                 490                 495

 Pro Asn Leu Ala Thr Thr Ala Gly His Thr Pro Leu His Ile Ala
                 500                 505                 510

 Ala Arg Glu Gly His Val Glu Thr Val Leu Ala Leu Leu Glu Lys
                 515                 520                 525

 Glu Ala Ser Gln Ala Cys Met Thr Lys Lys Gly Phe Thr Pro Leu
                 530                 535                 540

 His Val Ala Ala Lys Tyr Gly Lys Val Arg Val Ala Glu Leu Leu
                 545                 550                 555

 Leu Glu Arg Asp Ala His Pro Asn Ala Ala Gly Lys Asn Gly Leu
                 560                 565                 570

 Thr Pro Leu His Val Ala Val His His Asn Asn Leu Asp Ile Val
                 575                 580                 585

 Lys Leu Leu Leu Pro Arg Gly Gly Ser Pro His Ser Pro Ala Trp
                 590                 595                 600

 Asn Gly Tyr Thr Pro Leu His Ile Ala Ala Lys Gln Asn Gln Val
                 605                 610                 615

 Glu Val Ala Arg Ser Leu Leu Gln Tyr Gly Gly Ser Ala Asn Ala
                 620                 625                 630

 Glu Ser Val Gln Gly Val Thr Pro Leu His Leu Ala Ala Gln Glu
                 635                 640                 645

 Gly His Ala Glu Met Val Ala Leu Leu Leu Ser Lys Gln Ala Asn
                 650                 655                 660

 Gly Asn Leu Gly Asn Lys Ser Gly Leu Thr Pro Leu His Leu Val
                 665                 670                 675

 Ala Gln Glu Gly His Val Pro Val Ala Asp Val Leu Ile Lys His
                 680                 685                 690

 Gly Val Met Val Asp Ala Thr Thr Arg Met Gly Tyr Thr Pro Leu
                 695                 700                 705

 His Val Ala Ser His Tyr Gly Asn Ile Lys Leu Val Lys Phe Leu
                 710                 715                 720

 Leu Gln His Gln Ala Asp Val Asn Ala Lys Thr Lys Leu Gly Tyr
                 725                 730                 735

 Ser Pro Leu His Gln Ala Ala Gln Gln Gly His Thr Asp Ile Val
                 740                 745                 750

 Thr Leu Leu Leu Lys Asn Gly Ala Ser Pro Asn Glu Val Ser Ser
                 755                 760                 765

 Asp Gly Thr Thr Pro Leu Ala Ile Ala Lys Arg Leu Gly Tyr Ile
                 770                 775                 780

 Ser Val Thr Asp Val Leu Lys Val Val Thr Asp Glu Thr Ser Phe
                 785                 790                 795

 Val Leu Val Ser Asp Lys His Arg Met Ser Phe Pro Glu Thr Val
                 800                 805                 810

 Asp Glu Ile Leu Asp Val Ser Glu Asp Glu Gly Glu Glu Leu Ile
                 815                 820                 825

 Ser Phe Lys Ala Glu Arg Arg Asp Ser Arg Asp Val Asp Glu Glu
                 830                 835                 840

 Lys Glu Leu Leu Asp Phe Val Pro Lys Leu Asp Gln Val Val Glu
                 845                 850                 855

 Ser Pro Ala Ile Pro Arg Ile Pro Cys Ala Met Pro Glu Thr Val
                 860                 865                 870

 Val Ile Arg Ser Glu Glu Gln Glu Gln Ala Ser Lys Glu Tyr Asp
                 875                 880                 885

 Glu Asp Ser Leu Ile Pro Ser Ser Pro Ala Thr Glu Thr Ser Asp
                 890                 895                 900

 Asn Ile Ser Pro Val Ala Ser Pro Val His Thr Gly Phe Leu Val
                 905                 910                 915

 Ser Phe Met Val Asp Ala Arg Gly Gly Ser Met Arg Gly Ser Arg
                 920                 925                 930

 His Asn Gly Leu Arg Val Val Ile Pro Pro Arg Thr Cys Ala Ala
                 935                 940                 945

 Pro Thr Arg Ile Thr Cys Arg Leu Val Lys Pro Gln Lys Leu Ser
                 950                 955                 960

 Thr Pro Pro Pro Leu Ala Glu Glu Glu Gly Leu Ala Ser Arg Ile
                 965                 970                 975

 Ile Ala Leu Gly Pro Thr Gly Ala Gln Phe Leu Ser Pro Val Ile
                 980                 985                 990

 Val Glu Ile Pro His Phe Ala Ser His Gly Arg Gly Asp Arg Glu
                 995                1000                1005

 Leu Val Val Leu Arg Ser Glu Asn Gly Ser Val Trp Lys Glu His
                1010                1015                1020

 Arg Ser Arg Tyr Gly Glu Ser Tyr Leu Asp Gln Ile Leu Asn Gly
                1025                1030                1035

 Met Asp Glu Glu Leu Gly Ser Leu Glu Glu Leu Glu Lys Lys Arg
                1040                1045                1050

 Val Cys Arg Ile Ile Thr Thr Asp Phe Pro Leu Tyr Phe Val Ile
                1055                1060                1065

 Met Ser Arg Leu Cys Gln Asp Tyr Asp Ile Ile Gly Pro Glu Gly
                1070                1075                1080

 Gly Ser Leu Lys Ser Lys Leu Val Pro Leu Val Gln Ala Thr Phe
                1085                1090                1095

 Pro Glu Asn Ala Val Thr Lys Arg Val Lys Leu Ala Leu Gln Ala
                1100                1105                1110

 Gln Pro Val Pro Asp Glu Leu Val Thr Lys Leu Leu Gly Asn Gln
                1115                1120                1125

 Ala Thr Phe Ser Pro Ile Val Thr Val Glu Pro Arg Arg Arg Lys
                1130                1135                1140

 Phe His Arg Pro Ile Gly Leu Arg Ile Pro Leu Pro Pro Ser Trp
                1145                1150                1155

 Thr Asp Asn Pro Arg Asp Ser Gly Glu Gly Asp Thr Thr Ser Leu
                1160                1165                1170

 Arg Leu Leu Cys Ser Val Ile Gly Gly Thr Asp Gln Ala Gln Trp
                1175                1180                1185

 Glu Asp Ile Thr Gly Thr Thr Lys Leu Val Tyr Ala Asn Glu Cys
                1190                1195                1200

 Ala Asn Phe Thr Thr Asn Val Ser Ala Arg Phe Trp Leu Ser Asp
                1205                1210                1215

 Cys Pro Arg Thr Ala Glu Ala Val Asn Phe Ala Thr Leu Leu Tyr
                1220                1225                1230

 Lys Glu Leu Thr Ala Val Pro Tyr Met Ala Lys Phe Val Ile Phe
                1235                1240                1245

 Ala Lys Met Asn Asp Pro Arg Glu Gly Arg Leu Arg Cys Tyr Cys
                1250                1255                1260

 Met Thr Asp Asp Lys Val Asp Lys Thr Leu Glu Gln His Glu Asn
                1265                1270                1275

 Phe Val Glu Val Ala Arg Ser Arg Asp Ile Glu Val Leu Glu Gly
                1280                1285                1290

 Met Ser Leu Phe Ala Glu Leu Ser Gly Asn Leu Val Pro Val Lys
                1295                1300                1305

 Lys Ala Ala Gln Gln Arg Ser Phe His Phe Gln Ser Phe Arg Glu
                1310                1315                1320

 Asn Arg Leu Ala Met Pro Val Lys Val Arg Asp Ser Ser Arg Glu
                1325                1330                1335

 Pro Gly Gly Ser Leu Ser Phe Leu Arg Lys Ala Met Lys Tyr Glu
                1340                1345                1350

 Asp Thr Gln His Ile Leu Cys His Leu Asn Ile Thr Met Pro Pro
                1355                1360                1365

 Cys Ala Lys Gly Ser Gly Ala Glu Asp Arg Arg Arg Thr Pro Thr
                1370                1375                1380

 Pro Leu Ala Leu Arg Tyr Ser Ile Leu Ser Glu Ser Thr Pro Gly
                1385                1390                1395

 Ser Leu Ser Gly Thr Glu Gln Ala Glu Met Lys Met Ala Val Ile
                1400                1405                1410

 Ser Glu His Leu Gly Leu Ser Trp Ala Glu Leu Ala Arg Glu Leu
                1415                1420                1425

 Gln Phe Ser Val Glu Asp Ile Asn Arg Ile Arg Val Glu Asn Pro
                1430                1435                1440

 Asn Ser Leu Leu Glu Gln Ser Val Ala Leu Leu Asn Leu Trp Val
                1445                1450                1455

 Ile Arg Glu Gly Gln Asn Ala Asn Met Glu Asn Leu Tyr Thr Ala
                1460                1465                1470

 Leu Gln Ser Ile Asp Arg Gly Glu Ile Val Asn Met Leu Glu Gly
                1475                1480                1485

 Ser Gly Arg Gln Ser Arg Asn Leu Lys Pro Asp Arg Arg His Thr
                1490                1495                1500

 Asp Arg Asp Tyr Ser Leu Ser Pro Ser Gln Met Asn Gly His Gln
                1505                1510                1515

 Arg Gly Gln Ala Arg Ile Thr His Ser Pro Thr Val Ser Gln Val
                1520                1525                1530

 Thr Glu Arg Ser Gln Asp Arg Leu Gln Asp Trp Asp Ala Asp Gly
                1535                1540                1545

 Ser Ile Val Ser Tyr Leu Gln Asp Ala Ala Gln Gly Ser Trp Gln
                1550                1555                1560

 Glu Glu Val Thr Gln Gly Pro His Ser Phe Gln Gly Thr Ser Thr
                1565                1570                1575

 Met Thr Glu Gly Leu Glu Pro Gly Gly Ser Gln Glu Tyr Glu Lys
                1580                1585                1590

 Val Leu Val Ser Val Ser Glu His Thr Trp Thr Glu Gln Pro Glu
                1595                1600                1605

 Ala Glu Ser Ser Gln Ala Asp Arg Asp Arg Arg Gln Gln Gly Gln
                1610                1615                1620

 Glu Glu Gln Val Gln Glu Ala Lys Asn Thr Phe Thr Gln Val Val
                1625                1630                1635

 Gln Gly Asn Glu Phe Gln Asn Ile Pro Gly Glu Gln Val Thr Glu
                1640                1645                1650

 Glu Gln Phe Thr Asp Glu Gln Gly Asn Ile Val Thr Lys Lys Ile
                1655                1660                1665

 Ile Arg Lys Val Val Arg Gln Ile Asp Leu Ser Ser Ala Asp Ala
                1670                1675                1680

 Ala Gln Glu His Glu Glu Val Thr Val Glu Gly Pro Leu Glu Asp
                1685                1690                1695

 Pro Ser Glu Leu Glu Val Asp Ile Asp Tyr Phe Met Lys His Ser
                1700                1705                1710

 Lys Asp His Thr Ser Thr Pro Asn Pro
                1715

<210> 5258
<211> 1816
<212> DNA
<213> Homo sapien

<400> 5258
 cttctctgcc agaagatacc atttcaactt taacacagca tgatcgaaac 50

 atacaaccaa acttctcccc gatctgcggc cactggactg cccatcagca 100

 tgaaaatttt tatgtattta cttactgttt ttcttatcac ccagatgatt 150

 gggtcagcac tttttgctgt gtatcttcat agaaggttgg acaagataga 200

 agatgaaagg aatcttcatg aagattttgt attcatgaaa acgatacaga 250

 gatgcaacac aggagaaaga tccttatcct tactgaactg tgaggagatt 300

 aaaagccagt ttgaaggctt tgtgaaggat ataatgttaa acaaagagga 350

 gacgaagaaa gaaaacagct ttgaaatgca aaaaggtgat cagaatcctc 400

 aaattgcggc acatgtcata agtgaggcca gcagtaaaac aacatctgtg 450

 ttacagtggg ctgaaaaagg atactacacc atgagcaaca acttggtaac 500

 cctggaaaat gggaaacagc tgaccgttaa aagacaagga ctctattata 550

 tctatgccca agtcaccttc tgttccaatc gggaagcttc gagtcaagct 600

 ccatttatag ccagcctctg cctaaagtcc cccggtagat tcgagagaat 650

 cttactcaga gctgcaaata cccacagttc cgccaaacct tgcgggcaac 700

 aatccattca cttgggagga gtatttgaat tgcaaccagg tgcttcggtg 750

 tttgtcaatg tgactgatcc aagccaagtg agccatggca ctggcttcac 800

 gtcctttggc ttactcaaac tctgaacagt gtcaccttgc aggctgtggt 850

 ggagctgacg ctgggagtct tcataataca gcacagcggt taagcccacc 900

 ccctgttaac tgcctattta taaccctagg atcctcctta tggagaacta 950

 tttattatac actccaaggc atgtagaact gtaataagtg aattacaggt 1000

 cacatgaaac caaaacgggc cctgctccat aagagcttat atatctgaag 1050

 cagcaacccc actgatgcag acatccagag agtcctatga aaagacaagg 1100

 ccattatgca caggttgaat tctgagtaaa cagcagataa cttgccaagt 1150

 tcagttttgt ttctttgcgt gcagtgtctt tccatggata atgcatttga 1200

 tttatcagtg aagatgcaga agggaaatgg ggagcctcag ctcacattca 1250

 gttatggttg actctgggtt cctatggcct tgttggaggg ggccaggctc 1300

 tagaacgtct aacacagtgg agaaccgaaa cccccccccc cccccccgcc 1350

 accctctcgg acagttattc attctctttc aatctctctc tctccatctc 1400

 tctctttcag tctctctctc tcaacctctt tcttccaatc tctctttctc 1450

 aatctctctg tttccctttg tcagtctctt ccctccccca gtctctcttc 1500

 tcaatccccc tttctaacac acacacacac acacacacac acacacacac 1550

 acacacacac acacacacac acacacacac agagtcaggc cgttgctagt 1600

 cagttctctt ctttccaccc tgtccctatc tctaccacta tagatgaggg 1650

 tgaggagtag ggagtgcagc cctgagcctg cccactcctc attacgaaat 1700

 gactgtattt aaaggaaatc tattgtatct acctgcagtc tccattgttt 1750

 ccagagtgaa cttgtaatta tcttgttatt tattttttga ataataaaga 1800

 cctcttaaca ttaaaa 1816

<210> 5259
<211> 261
<212> PRT
<213> Homo sapien

<400> 5259
 Met Ile Glu Thr Tyr Asn Gln Thr Ser Pro Arg Ser Ala Ala Thr
   1               5                  10                  15

 Gly Leu Pro Ile Ser Met Lys Ile Phe Met Tyr Leu Leu Thr Val
                  20                  25                  30

 Phe Leu Ile Thr Gln Met Ile Gly Ser Ala Leu Phe Ala Val Tyr
                  35                  40                  45

 Leu His Arg Arg Leu Asp Lys Ile Glu Asp Glu Arg Asn Leu His
                  50                  55                  60

 Glu Asp Phe Val Phe Met Lys Thr Ile Gln Arg Cys Asn Thr Gly
                  65                  70                  75

 Glu Arg Ser Leu Ser Leu Leu Asn Cys Glu Glu Ile Lys Ser Gln
                  80                  85                  90

 Phe Glu Gly Phe Val Lys Asp Ile Met Leu Asn Lys Glu Glu Thr
                  95                 100                 105

 Lys Lys Glu Asn Ser Phe Glu Met Gln Lys Gly Asp Gln Asn Pro
                 110                 115                 120

 Gln Ile Ala Ala His Val Ile Ser Glu Ala Ser Ser Lys Thr Thr
                 125                 130                 135

 Ser Val Leu Gln Trp Ala Glu Lys Gly Tyr Tyr Thr Met Ser Asn
                 140                 145                 150

 Asn Leu Val Thr Leu Glu Asn Gly Lys Gln Leu Thr Val Lys Arg
                 155                 160                 165

 Gln Gly Leu Tyr Tyr Ile Tyr Ala Gln Val Thr Phe Cys Ser Asn
                 170                 175                 180

 Arg Glu Ala Ser Ser Gln Ala Pro Phe Ile Ala Ser Leu Cys Leu
                 185                 190                 195

 Lys Ser Pro Gly Arg Phe Glu Arg Ile Leu Leu Arg Ala Ala Asn
                 200                 205                 210

 Thr His Ser Ser Ala Lys Pro Cys Gly Gln Gln Ser Ile His Leu
                 215                 220                 225

 Gly Gly Val Phe Glu Leu Gln Pro Gly Ala Ser Val Phe Val Asn
                 230                 235                 240

 Val Thr Asp Pro Ser Gln Val Ser His Gly Thr Gly Phe Thr Ser
                 245                 250                 255

 Phe Gly Leu Leu Lys Leu
                 260

<210> 5260
<211> 1474
<212> DNA
<213> Homo sapien

<400> 5260
 agccctccca gtttccgcgc gcctctttgg cagctggtca catggtgagg 50

 gtgggggtga gggggcctct ctagcttgcg gcctgtgtct atggtcgggc 100

 cctctgcgtc cagctgctcc ggaccgagct cgggtgtatg gggccgtagg 150

 aaccggctcc ggggccccga taacgggccg cccccacagc accccgggct 200

 ggcgtgaggg tctcccttga tctgagaatg gctacctctc gatatgagcc 250

 agtggctgaa attggtgtcg gtgcctatgg gacagtgtac aaggcccgtg 300

 atccccacag tggccacttt gtggccctca agagtgtgag agtccccaat 350

 ggaggaggag gtggaggagg ccttcccatc agcacagttc gtgaggtggc 400

 tttactgagg cgactggagg cttttgagca tcccaatgtt gtccggctga 450

 tggacgtctg tgccacatcc cgaactgacc gggagatcaa ggtaaccctg 500

 gtgtttgagc atgtagacca ggacctaagg acatatctgg acaaggcacc 550

 cccaccaggc ttgccagccg aaacgatcaa ggatctgatg cgccagtttc 600

 taagaggcct agatttcctt catgccaatt gcatcgttca ccgagatctg 650

 aagccagaga acattctggt gacaagtggt ggaacagtca agctggctga 700

 ctttggcctg gccagaatct acagctacca gatggcactt acacccgtgg 750

 ttgttacact ctggtaccga gctcccgaag ttcttctgca gtccacatat 800

 gcaacacctg tggacatgtg gagtgttggc tgtatctttg cagagatgtt 850

 tcgtcgaaag cctctcttct gtggaaactc tgaagccgac cagttgggca 900

 aaatctttga cctgattggg ctgcctccag aggatgactg gcctcgagat 950

 gtatccctgc cccgtggagc ctttcccccc agagggcccc gcccagtgca 1000

 gtcggtggta cctgagatgg aggagtcggg agcacagctg ctgctggaaa 1050

 tgctgacttt taacccacac aagcgaatct ctgcctttcg agctctgcag 1100

 cactcttatc tacataagga tgaaggtaat ccggagtgag caatggagtg 1150

 gctgccatgg aaggaagaaa agctgccatt tcccttctgg acactgagag 1200

 ggcaatcttt gcctttatct ctgaggctat ggagggtcct cctccatctt 1250

 tctacagaga ttactttgct gccttaatga cattcccctc ccacctctcc 1300

 ttttgaggct tctccttctc cttcccattt ctctacacta aggggtatgt 1350

 tccctcttgt ccctttccct acctttatat ttggggtcct tttttataca 1400

 ggaaaaacaa aacaaagaaa taatggtctt tttttttttt ttaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaaa aaaa 1474

<210> 5261
<211> 303
<212> PRT
<213> Homo sapien

<400> 5261
 Met Ala Thr Ser Arg Tyr Glu Pro Val Ala Glu Ile Gly Val Gly
   1               5                  10                  15

 Ala Tyr Gly Thr Val Tyr Lys Ala Arg Asp Pro His Ser Gly His
                  20                  25                  30

 Phe Val Ala Leu Lys Ser Val Arg Val Pro Asn Gly Gly Gly Gly
                  35                  40                  45

 Gly Gly Gly Leu Pro Ile Ser Thr Val Arg Glu Val Ala Leu Leu
                  50                  55                  60

 Arg Arg Leu Glu Ala Phe Glu His Pro Asn Val Val Arg Leu Met
                  65                  70                  75

 Asp Val Cys Ala Thr Ser Arg Thr Asp Arg Glu Ile Lys Val Thr
                  80                  85                  90

 Leu Val Phe Glu His Val Asp Gln Asp Leu Arg Thr Tyr Leu Asp
                  95                 100                 105

 Lys Ala Pro Pro Pro Gly Leu Pro Ala Glu Thr Ile Lys Asp Leu
                 110                 115                 120

 Met Arg Gln Phe Leu Arg Gly Leu Asp Phe Leu His Ala Asn Cys
                 125                 130                 135

 Ile Val His Arg Asp Leu Lys Pro Glu Asn Ile Leu Val Thr Ser
                 140                 145                 150

 Gly Gly Thr Val Lys Leu Ala Asp Phe Gly Leu Ala Arg Ile Tyr
                 155                 160                 165

 Ser Tyr Gln Met Ala Leu Thr Pro Val Val Val Thr Leu Trp Tyr
                 170                 175                 180

 Arg Ala Pro Glu Val Leu Leu Gln Ser Thr Tyr Ala Thr Pro Val
                 185                 190                 195

 Asp Met Trp Ser Val Gly Cys Ile Phe Ala Glu Met Phe Arg Arg
                 200                 205                 210

 Lys Pro Leu Phe Cys Gly Asn Ser Glu Ala Asp Gln Leu Gly Lys
                 215                 220                 225

 Ile Phe Asp Leu Ile Gly Leu Pro Pro Glu Asp Asp Trp Pro Arg
                 230                 235                 240

 Asp Val Ser Leu Pro Arg Gly Ala Phe Pro Pro Arg Gly Pro Arg
                 245                 250                 255

 Pro Val Gln Ser Val Val Pro Glu Met Glu Glu Ser Gly Ala Gln
                 260                 265                 270

 Leu Leu Leu Glu Met Leu Thr Phe Asn Pro His Lys Arg Ile Ser
                 275                 280                 285

 Ala Phe Arg Ala Leu Gln His Ser Tyr Leu His Lys Asp Glu Gly
                 290                 295                 300

 Asn Pro Glu


<210> 5262
<211> 2921
<212> DNA
<213> Homo sapien

<400> 5262
 ccggctcgga gtgtgatcta agcaggtcgc gtaccttcct caggtgactc 50

 cggccacagc ccattgtccg cggccaccgg cggagtttag ccgcagacct 100

 cgaagcgccc cggggtcctt cccgaacggc agcggctgcg gcgggtccat 150

 ggagaagggc cctgtgcggg caccggcgga gaagccgcgg ggcgccaggt 200

 gcagcaatgg gttccccgag cgggatccgc cgcggcccgg gcccagcagg 250

 ccggcggaga agcccccgcg gcccgaggcc aagagcgcgc agcccgcgga 300

 cggctggaag ggcgagcggc cccgcagcga ggaggataac gagctgaacc 350

 tccctaacct ggcagccgcc tactcgtcca tcctgagctc gctgggcgag 400

 aacccccagc ggcaagggct gctcaagacg ccctggaggg cggcctcggc 450

 catgcagttc ttcaccaagg gctaccagga gaccatctca gatgtcctaa 500

 acgatgctat atttgatgaa gatcatgatg agatggtgat tgtgaaggac 550

 atagacatgt tttccatgtg tgagcatcac ttggttccat ttgttggaaa 600

 ggtccatatt ggttatcttc ctaacaagca agtccttggc ctcagcaaac 650

 ttgcgaggat tgtagaaatc tatagtagaa gactacaagt tcaggagcgc 700

 cttacaaaac aaattgctgt agcaatcacg gaagccttgc ggcctgctgg 750

 agtcggggta gtggttgaag caacacacat gtgtatggta atgcgaggtg 800

 tacagaaaat gaacagcaaa actgtgacca gcacaatgtt gggtgtgttc 850

 cgggaggatc caaagactcg ggaagagttc ctgactctca ttaggagctg 900

 agcttcattc agtgtgtgtg cgttggttgc cgatcgtact gccagtagca 950

 ttgtctgtct gtccggtctt gtttgtacat tccattttca attgttacag 1000

 atgtgaactt tattccttgt cactaattat atttaaaatt atttctagga 1050

 agtcaaataa atataataaa gggttgagcc tctactttct tcttgccacc 1100

 tttttgtggc aatattaaag tgaactgcta atagtgtaag tatgtgcaca 1150

 aaaccactgc cagataacca gaggggcctg ggaagggaga agaattagtg 1200

 tatttttttc aaatagtaca gtaatttgcc tcataagcat aggagcattg 1250

 ggaatgagag ggaactgtgc ccagtatact gttttttttc ttcctccaat 1300

 aaaagtggtg tagtgccgaa agtgctaaaa tatttagtgc ggtattgctc 1350

 tgtgaattca agttcaacag acttcacttt ggtcatgttt attaaaccac 1400

 cagtgacatt taaaaatata tttttagcag tcgtaatgtt agtcaccaag 1450

 ggaaggtggt ggaatgtcta tgtttttgat tttactgtga gttaaaaagg 1500

 cacatttcta ccttctattg tttttaaatt caagaatagg gaattagttc 1550

 ctggtgttgt ttacgagtgt attctcgtgt caacatacag ggatttagac 1600

 atttaactct ctgtgccttg ataagaatat catttagagt gtagatactt 1650

 ttgccttttt aaaaaagcca ttattttatg agacttagta ctcacactgc 1700

 aaataactag tcagctcagt tttaacttta taggtttatt gagtttcctt 1750

 tgtgtgatcc atgtagatgc ctcaaaatgt ttcttcttct tctttttttt 1800

 aatcttataa gatatttttc taagtatttc cagaaacatt tgagagtgcc 1850

 catcattttc aggtctgcag aaccatagct tccacgcacc tgaacgagca 1900

 cagaatgaac tgacggtgga agacattatg agctgtgtcc aacgttttaa 1950

 ccaaagcgta tcgtaccaac gatctgtgaa aatgcactgg aagcttctgg 2000

 tcccggtttc ctttgtggtc tatgtgggtc ttgtcctcat tgtaactccg 2050

 tatagatggt ataggtattt taatcctgga agctgttgcc ttattaatga 2100

 ttatcttaaa atttcctcca ttggggcagc gtgggccaaa ttaaaacaaa 2150

 caaaaccgca actcctccac agaaacacaa acacagttat tccatgaagt 2200

 ttagtatttg gttgacatag tgctcttcaa attcatccca ttaccctaaa 2250

 agtaataact ttgatgcttg ctttaacttt agtcccatct ctgccacttt 2300

 gatgctattt gggttatgat ggggcaagat ggcagaggta ttgggttttt 2350

 ttgttttttt ccattcctct ctacttctgt ttcctagctt tttctttctg 2400

 gagtttaagt acagtgatgg ttggcttgag taccttttta aatctagccc 2450

 agtataaaca ttagcctgct taatatttag acatttatag gtagaattct 2500

 gagcactcaa ctcatgtttg gcattttaaa gtaaaaacaa gtgtgacttc 2550

 gaggaccaaa gaaattgtca gctatacatt tatctttatg aactcattta 2600

 tattcctttt taatgactcg ttgttctaac atttcctaga agtgttctta 2650

 taaaggtcta atgtatccac aggctgttgt cttattagta aatgcaaagt 2700

 aatgactttg tctgttttac tctagtcttt agtacttcaa aattaccttt 2750

 tcatatccat gatcttgagt ccatttgggg gatttttaag aatttgatgt 2800

 atttcaatac actgttcaaa attaaattgt ttaattttat gtatgagtat 2850

 gtatgttcct gaagttggtc ctatttaaat tattaaacta ttgtaacttt 2900

 aaaaaaaaaa aaaaaaaaaa a 2921

<210> 5263
<211> 250
<212> PRT
<213> Homo sapien

<400> 5263
 Met Glu Lys Gly Pro Val Arg Ala Pro Ala Glu Lys Pro Arg Gly
   1               5                  10                  15

 Ala Arg Cys Ser Asn Gly Phe Pro Glu Arg Asp Pro Pro Arg Pro
                  20                  25                  30

 Gly Pro Ser Arg Pro Ala Glu Lys Pro Pro Arg Pro Glu Ala Lys
                  35                  40                  45

 Ser Ala Gln Pro Ala Asp Gly Trp Lys Gly Glu Arg Pro Arg Ser
                  50                  55                  60

 Glu Glu Asp Asn Glu Leu Asn Leu Pro Asn Leu Ala Ala Ala Tyr
                  65                  70                  75

 Ser Ser Ile Leu Ser Ser Leu Gly Glu Asn Pro Gln Arg Gln Gly
                  80                  85                  90

 Leu Leu Lys Thr Pro Trp Arg Ala Ala Ser Ala Met Gln Phe Phe
                  95                 100                 105

 Thr Lys Gly Tyr Gln Glu Thr Ile Ser Asp Val Leu Asn Asp Ala
                 110                 115                 120

 Ile Phe Asp Glu Asp His Asp Glu Met Val Ile Val Lys Asp Ile
                 125                 130                 135

 Asp Met Phe Ser Met Cys Glu His His Leu Val Pro Phe Val Gly
                 140                 145                 150

 Lys Val His Ile Gly Tyr Leu Pro Asn Lys Gln Val Leu Gly Leu
                 155                 160                 165

 Ser Lys Leu Ala Arg Ile Val Glu Ile Tyr Ser Arg Arg Leu Gln
                 170                 175                 180

 Val Gln Glu Arg Leu Thr Lys Gln Ile Ala Val Ala Ile Thr Glu
                 185                 190                 195

 Ala Leu Arg Pro Ala Gly Val Gly Val Val Val Glu Ala Thr His
                 200                 205                 210

 Met Cys Met Val Met Arg Gly Val Gln Lys Met Asn Ser Lys Thr
                 215                 220                 225

 Val Thr Ser Thr Met Leu Gly Val Phe Arg Glu Asp Pro Lys Thr
                 230                 235                 240

 Arg Glu Glu Phe Leu Thr Leu Ile Arg Ser
                 245                 250

<210> 5264
<211> 1350
<212> DNA
<213> Homo sapien

<400> 5264
 aggttaatct taaaagccca ggttacccgc ggaaatttat gctgtccggt 50

 caccgtgaca atgcagctga ggaacccaga actacatctg ggctgcgcgc 100

 ttgcgcttcg cttcctggcc ctcgtttcct gggacatccc tggggctaga 150

 gcactggaca atggattggc aaggacgcct accatgggct ggctgcactg 200

 ggagcgcttc atgtgcaacc ttgactgcca ggaagagcca gattcctgca 250

 tcagtgagaa gctcttcatg gagatggcag agctcatggt ctcagaaggc 300

 tggaaggatg caggttatga gtacctctgc attgatgact gttggatggc 350

 tccccaaaga gattcagaag gcagacttca ggcagaccct cagcgctttc 400

 ctcatgggat tcgccagcta gctaattatg ttcacagcaa aggactgaag 450

 ctagggattt atgcagatgt tggaaataaa acctgcgcag gcttccctgg 500

 gagttttgga tactacgaca ttgatgccca gacctttgct gactggggag 550

 tagatctgct aaaatttgat ggttgttact gtgacagttt ggaaaatttg 600

 gcagatggtt ataagcacat gtccttggcc ctgaatagga ctggcagaag 650

 cattgtgtac tcctgtgagt ggcctcttta tatgtggccc tttcaaaagc 700

 ccaattatac agaaatccga cagtactgca atcactggcg aaattttgct 750

 gacattgatg attcctggaa aagtataaag agtatcttgg actggacatc 800

 ttttaaccag gagagaattg ttgatgttgc tggaccaggg ggttggaatg 850

 acccagatat gttagtgatt ggcaactttg gcctcagctg gaatcagcaa 900

 gtaactcaga tggccctctg ggctatcatg gctgctcctt tattcatgtc 950

 taatgacctc cgacacatca gccctcaagc caaagctctc cttcaggata 1000

 aggacgtaat tgccatcaat caggacccct tgggcaagca agggtaccag 1050

 cttagacagg gagacaactt tgaagtgtgg gaacgacctc tctcaggctt 1100

 agcctgggct gtagctatga taaaccggca ggagattggt ggacctcgct 1150

 cttataccat cgcagttgct tccctgggta aaggagtggc ctgtaatcct 1200

 gcctgcttca tcacacagct cctccctgtg aaaaggaagc tagggttcta 1250

 tgaatggact tcaaggttaa gaagtcacat aaatcccaca ggcactgttt 1300

 tgcttcagct agaaaataca atgcagatgt cattaaaaga cttactttaa 1350

<210> 5265
<211> 429
<212> PRT
<213> Homo sapien

<400> 5265
 Met Gln Leu Arg Asn Pro Glu Leu His Leu Gly Cys Ala Leu Ala
   1               5                  10                  15

 Leu Arg Phe Leu Ala Leu Val Ser Trp Asp Ile Pro Gly Ala Arg
                  20                  25                  30

 Ala Leu Asp Asn Gly Leu Ala Arg Thr Pro Thr Met Gly Trp Leu
                  35                  40                  45

 His Trp Glu Arg Phe Met Cys Asn Leu Asp Cys Gln Glu Glu Pro
                  50                  55                  60

 Asp Ser Cys Ile Ser Glu Lys Leu Phe Met Glu Met Ala Glu Leu
                  65                  70                  75

 Met Val Ser Glu Gly Trp Lys Asp Ala Gly Tyr Glu Tyr Leu Cys
                  80                  85                  90

 Ile Asp Asp Cys Trp Met Ala Pro Gln Arg Asp Ser Glu Gly Arg
                  95                 100                 105

 Leu Gln Ala Asp Pro Gln Arg Phe Pro His Gly Ile Arg Gln Leu
                 110                 115                 120

 Ala Asn Tyr Val His Ser Lys Gly Leu Lys Leu Gly Ile Tyr Ala
                 125                 130                 135

 Asp Val Gly Asn Lys Thr Cys Ala Gly Phe Pro Gly Ser Phe Gly
                 140                 145                 150

 Tyr Tyr Asp Ile Asp Ala Gln Thr Phe Ala Asp Trp Gly Val Asp
                 155                 160                 165

 Leu Leu Lys Phe Asp Gly Cys Tyr Cys Asp Ser Leu Glu Asn Leu
                 170                 175                 180

 Ala Asp Gly Tyr Lys His Met Ser Leu Ala Leu Asn Arg Thr Gly
                 185                 190                 195

 Arg Ser Ile Val Tyr Ser Cys Glu Trp Pro Leu Tyr Met Trp Pro
                 200                 205                 210

 Phe Gln Lys Pro Asn Tyr Thr Glu Ile Arg Gln Tyr Cys Asn His
                 215                 220                 225

 Trp Arg Asn Phe Ala Asp Ile Asp Asp Ser Trp Lys Ser Ile Lys
                 230                 235                 240

 Ser Ile Leu Asp Trp Thr Ser Phe Asn Gln Glu Arg Ile Val Asp
                 245                 250                 255

 Val Ala Gly Pro Gly Gly Trp Asn Asp Pro Asp Met Leu Val Ile
                 260                 265                 270

 Gly Asn Phe Gly Leu Ser Trp Asn Gln Gln Val Thr Gln Met Ala
                 275                 280                 285

 Leu Trp Ala Ile Met Ala Ala Pro Leu Phe Met Ser Asn Asp Leu
                 290                 295                 300

 Arg His Ile Ser Pro Gln Ala Lys Ala Leu Leu Gln Asp Lys Asp
                 305                 310                 315

 Val Ile Ala Ile Asn Gln Asp Pro Leu Gly Lys Gln Gly Tyr Gln
                 320                 325                 330

 Leu Arg Gln Gly Asp Asn Phe Glu Val Trp Glu Arg Pro Leu Ser
                 335                 340                 345

 Gly Leu Ala Trp Ala Val Ala Met Ile Asn Arg Gln Glu Ile Gly
                 350                 355                 360

 Gly Pro Arg Ser Tyr Thr Ile Ala Val Ala Ser Leu Gly Lys Gly
                 365                 370                 375

 Val Ala Cys Asn Pro Ala Cys Phe Ile Thr Gln Leu Leu Pro Val
                 380                 385                 390

 Lys Arg Lys Leu Gly Phe Tyr Glu Trp Thr Ser Arg Leu Arg Ser
                 395                 400                 405

 His Ile Asn Pro Thr Gly Thr Val Leu Leu Gln Leu Glu Asn Thr
                 410                 415                 420

 Met Gln Met Ser Leu Lys Asp Leu Leu
                 425

<210> 5266
<211> 2075
<212> DNA
<213> Homo sapien

<400> 5266
 gccataaagg ccgccgcgcg cccacgcgcc tcgcttgctg cgcgctgccg 50

 gcgctccttc ctcctcggct cgcgtctcac tcagtgtacc ttctagtccc 100

 gccatggccg ctctcacccg ggacccccag ttccagaagc tgcagcaatg 150

 gtaccgcgag caccgctccg agctgaacct gcgccgcctc ttcgatgcca 200

 acaaggaccg cttcaaccac ttcagcttga ccctcaacac caaccatggg 250

 catatcctgg tggattactc caagaacctg gtgacggagg acgtgatgcg 300

 gatgctggtg gacttggcca agtccagggg cgtggaggcc gcccgggagc 350

 ggatgttcaa tggtgagaag atcaactaca ccgagggtcg agccgtgctg 400

 cacgtggctc tgcggaaccg gtcaaacaca cccatcctgg tagacggcaa 450

 ggatgtgatg ccagaggtca acaaggttct ggacaagatg aagtctttct 500

 gccagcgtgt ccggagcggt gactggaagg ggtacacagg caagaccatc 550

 acggacgtca tcaacattgg cattggcggc tccgacctgg gacccctcat 600

 ggtgactgaa gcccttaagc catactcttc aggaggtccc cgcgtctggt 650

 atgtctccaa cattgatgga actcacattg ccaaaaccct ggcccagctg 700

 aaccccgagt cctccctgtt catcattgcc tccaagacct ttactaccca 750

 ggagaccatc acgaatgcag agacggcgaa ggagtggttt ctccaggcgg 800

 ccaaggatcc ttctgcagtg gcgaagcact ttgttgccct gtctactaac 850

 acaaccaaag tgaaggagtt tggaattgac cctcaaaaca tgttcgagtt 900

 ctgggattgg gtgggaggac gctactcgct gtggtcggcc atcggactct 950

 ccattgccct gcacgtgggt tttgacaact tcgagcagct gctctcgggg 1000

 gctcactgga tggaccagca cttccgcacg acgcccctgg agaagaacgc 1050

 ccccgtcttg ctggccctgc tgggtatctg gtacatcaac tgctttgggt 1100

 gtgagacaca cgccatgctg ccctatgacc agtacctgca ccgctttgct 1150

 gcgtacttcc agcagggcga catggagtcc aatgggaaat acatcaccaa 1200

 atctggaacc cgtgtggacc accagacagg ccccattgtg tggggggagc 1250

 cagggaccaa tggccagcat gctttttacc agctcatcca ccaaggcacc 1300

 aagatgatac cctgtgactt cctcatcccg gtccagaccc agcaccccat 1350

 acggaagggt ctgcatcaca agatcctcct ggccaacttc ttggcccaga 1400

 cagaggccct gatgagggga aaatcgacgg aggaggcccg aaaggagctc 1450

 caggctgcgg gcaagagtcc agaggacctt gagaggctgc tgccacataa 1500

 ggtctttgaa ggaaatcgcc caaccaactc tattgtgttc accaagctca 1550

 caccattcat gcttggagcc ttggtcgcca tgtatgagca caagatcttc 1600

 gttcagggca tcatctggga catcaacagc tttgaccagt ggggagtgga 1650

 gctgggaaag cagctggcta agaaaataga gcctgagctt gatggcagtg 1700

 ctcaagtgac ctctcacgac gcttctacca atgggctcat caacttcatc 1750

 aagcagcagc gcgaggccag agtccaataa actcgtgctc atctgcagcc 1800

 tcctctgtga ctcccctttc tcttctcgtc cctcctcccc ggagccggca 1850

 ctgcatgttc ctggacacca cccagagcac cctctggttg tgggcttgga 1900

 ccacgagccc ttagcaggga aggctggtct cccccagcct aacccccagc 1950

 ccctccatgt ctatgctccc tctgtgttag aattggctga agtgtttttg 2000

 tgcagctgac ttttctgacc catgttcacg ttgttcacat cccatgtaga 2050

 aaaataaaga tgccacggag gaggt 2075

<210> 5267
<211> 558
<212> PRT
<213> Homo sapien

<400> 5267
 Met Ala Ala Leu Thr Arg Asp Pro Gln Phe Gln Lys Leu Gln Gln
   1               5                  10                  15

 Trp Tyr Arg Glu His Arg Ser Glu Leu Asn Leu Arg Arg Leu Phe
                  20                  25                  30

 Asp Ala Asn Lys Asp Arg Phe Asn His Phe Ser Leu Thr Leu Asn
                  35                  40                  45

 Thr Asn His Gly His Ile Leu Val Asp Tyr Ser Lys Asn Leu Val
                  50                  55                  60

 Thr Glu Asp Val Met Arg Met Leu Val Asp Leu Ala Lys Ser Arg
                  65                  70                  75

 Gly Val Glu Ala Ala Arg Glu Arg Met Phe Asn Gly Glu Lys Ile
                  80                  85                  90

 Asn Tyr Thr Glu Gly Arg Ala Val Leu His Val Ala Leu Arg Asn
                  95                 100                 105

 Arg Ser Asn Thr Pro Ile Leu Val Asp Gly Lys Asp Val Met Pro
                 110                 115                 120

 Glu Val Asn Lys Val Leu Asp Lys Met Lys Ser Phe Cys Gln Arg
                 125                 130                 135

 Val Arg Ser Gly Asp Trp Lys Gly Tyr Thr Gly Lys Thr Ile Thr
                 140                 145                 150

 Asp Val Ile Asn Ile Gly Ile Gly Gly Ser Asp Leu Gly Pro Leu
                 155                 160                 165

 Met Val Thr Glu Ala Leu Lys Pro Tyr Ser Ser Gly Gly Pro Arg
                 170                 175                 180

 Val Trp Tyr Val Ser Asn Ile Asp Gly Thr His Ile Ala Lys Thr
                 185                 190                 195

 Leu Ala Gln Leu Asn Pro Glu Ser Ser Leu Phe Ile Ile Ala Ser
                 200                 205                 210

 Lys Thr Phe Thr Thr Gln Glu Thr Ile Thr Asn Ala Glu Thr Ala
                 215                 220                 225

 Lys Glu Trp Phe Leu Gln Ala Ala Lys Asp Pro Ser Ala Val Ala
                 230                 235                 240

 Lys His Phe Val Ala Leu Ser Thr Asn Thr Thr Lys Val Lys Glu
                 245                 250                 255

 Phe Gly Ile Asp Pro Gln Asn Met Phe Glu Phe Trp Asp Trp Val
                 260                 265                 270

 Gly Gly Arg Tyr Ser Leu Trp Ser Ala Ile Gly Leu Ser Ile Ala
                 275                 280                 285

 Leu His Val Gly Phe Asp Asn Phe Glu Gln Leu Leu Ser Gly Ala
                 290                 295                 300

 His Trp Met Asp Gln His Phe Arg Thr Thr Pro Leu Glu Lys Asn
                 305                 310                 315

 Ala Pro Val Leu Leu Ala Leu Leu Gly Ile Trp Tyr Ile Asn Cys
                 320                 325                 330

 Phe Gly Cys Glu Thr His Ala Met Leu Pro Tyr Asp Gln Tyr Leu
                 335                 340                 345

 His Arg Phe Ala Ala Tyr Phe Gln Gln Gly Asp Met Glu Ser Asn
                 350                 355                 360

 Gly Lys Tyr Ile Thr Lys Ser Gly Thr Arg Val Asp His Gln Thr
                 365                 370                 375

 Gly Pro Ile Val Trp Gly Glu Pro Gly Thr Asn Gly Gln His Ala
                 380                 385                 390

 Phe Tyr Gln Leu Ile His Gln Gly Thr Lys Met Ile Pro Cys Asp
                 395                 400                 405

 Phe Leu Ile Pro Val Gln Thr Gln His Pro Ile Arg Lys Gly Leu
                 410                 415                 420

 His His Lys Ile Leu Leu Ala Asn Phe Leu Ala Gln Thr Glu Ala
                 425                 430                 435

 Leu Met Arg Gly Lys Ser Thr Glu Glu Ala Arg Lys Glu Leu Gln
                 440                 445                 450

 Ala Ala Gly Lys Ser Pro Glu Asp Leu Glu Arg Leu Leu Pro His
                 455                 460                 465

 Lys Val Phe Glu Gly Asn Arg Pro Thr Asn Ser Ile Val Phe Thr
                 470                 475                 480

 Lys Leu Thr Pro Phe Met Leu Gly Ala Leu Val Ala Met Tyr Glu
                 485                 490                 495

 His Lys Ile Phe Val Gln Gly Ile Ile Trp Asp Ile Asn Ser Phe
                 500                 505                 510

 Asp Gln Trp Gly Val Glu Leu Gly Lys Gln Leu Ala Lys Lys Ile
                 515                 520                 525

 Glu Pro Glu Leu Asp Gly Ser Ala Gln Val Thr Ser His Asp Ala
                 530                 535                 540

 Ser Thr Asn Gly Leu Ile Asn Phe Ile Lys Gln Gln Arg Glu Ala
                 545                 550                 555

 Arg Val Gln


<210> 5268
<211> 1451
<212> DNA
<213> Homo sapien

<400> 5268
 gaagagcaag cgccatgttg aagccatcat taccattcac atccctctta 50

 ttcctgcagc tgcccctgct gggagtgggg ctgaacacga caattctgac 100

 gcccaatggg aatgaagaca ccacagctga tttcttcctg accactatgc 150

 ccactgactc cctcagtgtt tccactctgc ccctcccaga ggttcagtgt 200

 tttgtgttca atgtcgagta catgaattgc acttggaaca gcagctctga 250

 gccccagcct accaacctca ctctgcatta ttggtacaag aactcggata 300

 atgataaagt ccagaagtgc agccactatc tattctctga agaaatcact 350

 tctggctgtc agttgcaaaa aaaggagatc cacctctacc aaacatttgt 400

 tgttcagctc caggacccac gggaacccag gagacaggcc acacagatgc 450

 taaaactgca gaatctggtg atcccctggg ctccagagaa cctaacactt 500

 cacaaactga gtgaatccca gctagaactg aactggaaca acagattctt 550

 gaaccactgt ttggagcact tggtgcagta ccggactgac tgggaccaca 600

 gctggactga acaatcagtg gattatagac ataagttctc cttgcctagt 650

 gtggatgggc agaaacgcta cacgtttcgt gttcggagcc gctttaaccc 700

 actctgtgga agtgctcagc attggagtga atggagccac ccaatccact 750

 gggggagcaa tacttcaaaa gagaatcctt tcctgtttgc attggaagcc 800

 gtggttatct ctgttggctc catgggattg attatcagcc ttctctgtgt 850

 gtatttctgg ctggaacgga cgatgccccg aattcccacc ctgaagaacc 900

 tagaggatct tgttactgaa taccacggga acttttcggc ctggagtggt 950

 gtgtctaagg gactggctga gagtctgcag ccagactaca gtgaacgact 1000

 ctgcctcgtc agtgagattc ccccaaaagg aggggccctt ggggaggggc 1050

 ctggggcctc cccatgcaac cagcatagcc cctactgggc ccccccatgt 1100

 tacaccctaa agcctgaaac ctgaacccca atcctctgac agaagaaccc 1150

 cagggtcctg tagccctaag tggtactaac tttccttcat tcaacccacc 1200

 tgcgtctcat actcacctca ccccactgtg gctgatttgg aattttgtgc 1250

 ccccatgtaa gcaccccttc atttggcatt ccccacttga gaattaccct 1300

 tttgccccga acatgttttt cttctccctc agtctggccc ttccttttcg 1350

 caggattctt cctccctccc tctttccctc ccttcctctt tccatctacc 1400

 ctccgattgt tcctgaaccg atgagaaata aagtttctgt tgataatcat 1450

 c 1451

<210> 5269
<211> 369
<212> PRT
<213> Homo sapien

<400> 5269
 Met Leu Lys Pro Ser Leu Pro Phe Thr Ser Leu Leu Phe Leu Gln
   1               5                  10                  15

 Leu Pro Leu Leu Gly Val Gly Leu Asn Thr Thr Ile Leu Thr Pro
                  20                  25                  30

 Asn Gly Asn Glu Asp Thr Thr Ala Asp Phe Phe Leu Thr Thr Met
                  35                  40                  45

 Pro Thr Asp Ser Leu Ser Val Ser Thr Leu Pro Leu Pro Glu Val
                  50                  55                  60

 Gln Cys Phe Val Phe Asn Val Glu Tyr Met Asn Cys Thr Trp Asn
                  65                  70                  75

 Ser Ser Ser Glu Pro Gln Pro Thr Asn Leu Thr Leu His Tyr Trp
                  80                  85                  90

 Tyr Lys Asn Ser Asp Asn Asp Lys Val Gln Lys Cys Ser His Tyr
                  95                 100                 105

 Leu Phe Ser Glu Glu Ile Thr Ser Gly Cys Gln Leu Gln Lys Lys
                 110                 115                 120

 Glu Ile His Leu Tyr Gln Thr Phe Val Val Gln Leu Gln Asp Pro
                 125                 130                 135

 Arg Glu Pro Arg Arg Gln Ala Thr Gln Met Leu Lys Leu Gln Asn
                 140                 145                 150

 Leu Val Ile Pro Trp Ala Pro Glu Asn Leu Thr Leu His Lys Leu
                 155                 160                 165

 Ser Glu Ser Gln Leu Glu Leu Asn Trp Asn Asn Arg Phe Leu Asn
                 170                 175                 180

 His Cys Leu Glu His Leu Val Gln Tyr Arg Thr Asp Trp Asp His
                 185                 190                 195

 Ser Trp Thr Glu Gln Ser Val Asp Tyr Arg His Lys Phe Ser Leu
                 200                 205                 210

 Pro Ser Val Asp Gly Gln Lys Arg Tyr Thr Phe Arg Val Arg Ser
                 215                 220                 225

 Arg Phe Asn Pro Leu Cys Gly Ser Ala Gln His Trp Ser Glu Trp
                 230                 235                 240

 Ser His Pro Ile His Trp Gly Ser Asn Thr Ser Lys Glu Asn Pro
                 245                 250                 255

 Phe Leu Phe Ala Leu Glu Ala Val Val Ile Ser Val Gly Ser Met
                 260                 265                 270

 Gly Leu Ile Ile Ser Leu Leu Cys Val Tyr Phe Trp Leu Glu Arg
                 275                 280                 285

 Thr Met Pro Arg Ile Pro Thr Leu Lys Asn Leu Glu Asp Leu Val
                 290                 295                 300

 Thr Glu Tyr His Gly Asn Phe Ser Ala Trp Ser Gly Val Ser Lys
                 305                 310                 315

 Gly Leu Ala Glu Ser Leu Gln Pro Asp Tyr Ser Glu Arg Leu Cys
                 320                 325                 330

 Leu Val Ser Glu Ile Pro Pro Lys Gly Gly Ala Leu Gly Glu Gly
                 335                 340                 345

 Pro Gly Ala Ser Pro Cys Asn Gln His Ser Pro Tyr Trp Ala Pro
                 350                 355                 360

 Pro Cys Tyr Thr Leu Lys Pro Glu Thr
                 365

<210> 5270
<211> 5611
<212> DNA
<213> Homo sapien

<400> 5270
 gcgcgaccgt cccgggggtg gggccgggcg cagcggcgag aggaggcgaa 50

 ggtggctgcg gtagcagcag cgcggcagcc tcggacccag cccggagcgc 100

 agggcggccg ctgcaggtcc ccgctcccct ccccgtgcgt ccgcccatgg 150

 ccgccgccgg gcagctgtgc ttgctctacc tgtcggcggg gctcctgtcc 200

 cggctcggcg cagccttcaa cttggacact cgggaggaca acgtgatccg 250

 gaaatatgga gaccccggga gcctcttcgg cttctcgctg gccatgcact 300

 ggcaactgca gcccgaggac aagcggctgt tgctcgtggg ggccccgcgc 350

 ggagaagcgc ttccactgca gagagccaac agaacgggag ggctgtacag 400

 ctgcgacatc accgcccggg ggccatgcac gcggatcgag tttgataacg 450

 atgctgaccc cacgtcagaa agcaaggaag atcagtggat gggggtcacc 500

 gtccagagcc aaggtccagg gggcaaggtc gtgacatgtg ctcaccgata 550

 tgaaaaaagg cagcatgtta atacgaagca ggaatcccga gacatctttg 600

 ggcggtgtta tgtcctgagt cagaatctca ggattgaaga cgatatggat 650

 gggggagatt ggagcttttg tgatgggcga ttgagaggcc atgagaaatt 700

 tggctcttgc cagcaaggtg tagcagctac ttttactaaa gactttcatt 750

 acattgtatt tggagccccg ggtacttata actggaaagg gattgttcgt 800

 gtagagcaaa agaataacac tttttttgac atgaacatct ttgaagatgg 850

 gccttatgaa gttggtggag agactgagca tgatgaaagt ctcgttcctg 900

 ttcctgctaa cagttactta ggtttttctt tggactcagg gaaaggtatt 950

 gtttctaaag atgagatcac ttttgtatct ggtgctccca gagccaatca 1000

 cagtggagcc gtggttttgc tgaagagaga catgaagtct gcacatctcc 1050

 tccctgagca catattcgat ggagaaggtc tggcctcttc atttggctat 1100

 gatgtggcgg tggtggacct caacaaggat gggtggcaag atatagttat 1150

 tggagcccca cagtattttg atagagatgg agaagttgga ggtgcagtgt 1200

 atgtctacat gaaccagcaa ggcagatgga ataatgtgaa gccaattcgt 1250

 cttaatggaa ccaaagattc tatgtttggc attgcagtaa aaaatattgg 1300

 agatattaat caagatggct acccagatat tgcagttgga gctccgtatg 1350

 atgacttggg aaaggttttt atctatcatg gatctgcaaa tggaataaat 1400

 accaaaccaa cacaggttct caagggtata tcaccttatt ttggatattc 1450

 aattgctgga aacatggacc ttgatcgaaa ttcctaccct gatgttgctg 1500

 ttggttccct ctcagattca gtaactattt tcagatcccg gcctgtgatt 1550

 aatattcaga aaaccatcac agtaactcct aacagaattg acctccgcca 1600

 gaaaacagcg tgtggggcgc ctagtgggat atgcctccag gttaaatcct 1650

 gttttgaata tactgctaac cccgctggtt ataatccttc aatatcaatt 1700

 gtgggcacac ttgaagctga aaaagaaaga agaaaatctg ggctatcctc 1750

 aagagttcag tttcgaaacc aaggttctga gcccaaatat actcaagaac 1800

 taactctgaa gaggcagaaa cagaaagtgt gcatggagga aaccctgtgg 1850

 ctacaggata atatcagaga taaactgcgt cccattccca taactgcctc 1900

 agtggagatc caagagccaa gctctcgtag gcgagtgaat tcacttccag 1950

 aagttcttcc aattctgaat tcagatgaac ccaagacagc tcatattgat 2000

 gttcacttct taaaagaggg atgtggagac gacaatgtat gtaacagcaa 2050

 ccttaaacta gaatataaat tttgcacccg agaaggaaat caagacaaat 2100

 tttcttattt accaattcaa aaaggtgtac cagaactagt tctaaaagat 2150

 cagaaggata ttgctttaga aataacagtg acaaacagcc cttccaaccc 2200

 aaggaatccc acaaaagatg gcgatgacgc ccatgaggct aaactgattg 2250

 caacgtttcc agacacttta acctattctg catatagaga actgagggct 2300

 ttccctgaga aacagttgag ttgtgttgcc aaccagaatg gctcgcaagc 2350

 tgactgtgag ctcggaaatc cttttaaaag aaattcaaat gtcacttttt 2400

 atttggtttt aagtacaact gaagtcacct ttgacacccc atatctggat 2450

 attaatctga agttagaaac aacaagcaat caagataatt tggctccaat 2500

 tacagctaaa gcaaaagtgg ttattgaact gcttttatcg gtctcgggag 2550

 ttgctaaacc ttcccaggtg tattttggag gtacagttgt tggcgagcaa 2600

 gctatgaaat ctgaagatga agtgggaagt ttaatagagt atgaattcag 2650

 ggtaataaac ttaggtaaac ctcttacaaa cctcggcaca gcaaccttga 2700

 acattcagtg gccaaaagaa attagcaatg ggaaatggtt gctttatttg 2750

 gtgaaagtag aatccaaagg attggaaaag gtaacttgtg agccacaaaa 2800

 ggagataaac tccctgaacc taacggagtc tcacaactca agaaagaaac 2850

 gggaaattac tgaaaaacag atagatgata acagaaaatt ttctttattt 2900

 gctgaaagaa aataccagac tcttaactgt agcgtgaacg tgaactgtgt 2950

 gaacatcaga tgcccgctgc gggggctgga cagcaaggcg tctcttattt 3000

 tgcgctcgag gttatggaac agcacatttc tagaggaata ttccaaactg 3050

 aactacttgg acattctcat gcgagccttc attgatgtga ctgctgctgc 3100

 cgaaaatatc aggctgccaa atgcaggcac tcaggttcga gtgactgtgt 3150

 ttccctcaaa gactgtagct cagtattcgg gagtaccttg gtggatcatc 3200

 ctagtggcta ttctcgctgg gatcttgatg cttgctttat tagtgtttat 3250

 actatggaag tgtggtttct tcaagagaaa taagaaagat cattatgatg 3300

 ccacatatca caaggctgag atccatgctc agccatctga taaagagagg 3350

 cttacttctg atgcatagta ttgatctact tctgtaattg tgtggattct 3400

 ttaaacgctc taggtacgat gacagtgttc cccgatacca tgctgtaagg 3450

 atccggaaag aagagcgaga gatcaaagat gaaaagtata ttgataacct 3500

 tgaaaaaaaa cagtggatca caaagtggaa cagaaatgaa agctactcat 3550

 agcgggggcc taaaaaaaaa aaagcttcac agtacccaaa ctgctttttc 3600

 caactcagaa attcaatttg gatttaaaag cctgctcaat ccctgaggac 3650

 tgatttcaga gtgactacac acagtacgaa cctacagttt taactgtgga 3700

 tattgttacg tagcctaagg ctcctgtttt gcacagccaa atttaaaact 3750

 gttggaatgg atttttcttt aactgccgta atttaacttt ctgggttgcc 3800

 tttgtttttg gcgtggctga cttacatcat gtgttgggga agggcctgcc 3850

 cagttgcact caggtgacat cctccagata gtgtagctga ggaggcacct 3900

 acactcacct gcactaacag agtggccgtc ctaacctcgg gcctgctgcg 3950

 cagacgtcca tcacgttagc tgtcccacat cacaagacta tgccattggg 4000

 gtagttgtgt ttcaacggaa agtgctgtct taaactaaat gtgcaataga 4050

 aggtgatgtt gccatcctac cgtcttttcc tgtttcctag ctgtgtgaat 4100

 acctgctcac gtcaaatgca tacaagtttc attctccctt tcactaaaaa 4150

 cacacaggtg caacagactt gaatgctagt tatacttatt tgtatatggt 4200

 atttattttt tcttttcttt acaaaccatt ttgttattga ctaacaggcc 4250

 aaagagtctc cagtttaccc ttcaggttgg tttaatcaat cagaattaga 4300

 attagagcat gggagggtca tcactatgac ctaaattatt tactgcaaaa 4350

 agaaaatctt tataaatgta ccagagagag ttgttttaat aacttatcta 4400

 taaactataa cctctccttc atgacagcct ccaccccaca acccaaaagg 4450

 tttaagaaat agaattataa ctgtaaagat gtttatttca ggcattggat 4500

 attttttact ttagaagcct gcataatgtt tctggattta catactgtaa 4550

 cattcaggaa ttcttggaga agatgggttt attcactgaa ctctagtgcg 4600

 gtttactcac tgctgcaaat actgtatatt caggacttga aagaaatggt 4650

 gaatgcctat ggaactagtg gatccaaact gatccagtat aagactactg 4700

 aatctgctac caaaacagtt aatcagtgag tcgagtgttc tattttttgt 4750

 tttgtttcct cccctatctg tattcccaaa aattactttg gggctaattt 4800

 aacaagaact ttaaattgtg ttttaattgt aaaaatggca gggggtggaa 4850

 ttattactct atacattcaa cagagactga atagatatga aagctgattt 4900

 tttttaatta ccatgcttca caatgttaag ttatatgggg agcaacagca 4950

 aacaggtgct aatttgtttt ggatatagta taagcagtgt ctgtgttttg 5000

 aaagaataga acacagtttg tagtgccact gttgttttgg ggggggcttt 5050

 ttttcttttt ccggaaaatc cttaaacctt aagatactaa ggacgttgtt 5100

 ttggttgtac ttggaattct tagtcacaaa atatattttg tttacaaaaa 5150

 tttctgtaaa acaggttata acagtgttta aagtctcagt ttcttgcttg 5200

 gggaacttgt gtccctaatg tgttagattg ctagattgct aaggagctga 5250

 tacttgacag ttttttagac ctgtgttact aaaaaaaaga tgaatgtcgg 5300

 aaaagggtgt tgggagggtg gtcaacaaag aaacaaagat gttatggtgt 5350

 ttagacttat ggttgttaaa aatgtcatct caagtcaagt cactggtctg 5400

 tttgcatttg atacattttt gtactaacta gcattgtaaa attatttcat 5450

 gattagaaat tacctgtgga tatttgtata aaagtgtgaa ataaattttt 5500

 tataaaagtg ttcattgttt cgtaacacag cattgtatat gtgaagcaaa 5550

 ctctaaaatt ataaatgaca acctgaatta tctatttcat caaaaaaaaa 5600

 aaaaaaaaaa a 5611

<210> 5271
<211> 1073
<212> PRT
<213> Homo sapien

<400> 5271
 Met Ala Ala Ala Gly Gln Leu Cys Leu Leu Tyr Leu Ser Ala Gly
   1               5                  10                  15

 Leu Leu Ser Arg Leu Gly Ala Ala Phe Asn Leu Asp Thr Arg Glu
                  20                  25                  30

 Asp Asn Val Ile Arg Lys Tyr Gly Asp Pro Gly Ser Leu Phe Gly
                  35                  40                  45

 Phe Ser Leu Ala Met His Trp Gln Leu Gln Pro Glu Asp Lys Arg
                  50                  55                  60

 Leu Leu Leu Val Gly Ala Pro Arg Gly Glu Ala Leu Pro Leu Gln
                  65                  70                  75

 Arg Ala Asn Arg Thr Gly Gly Leu Tyr Ser Cys Asp Ile Thr Ala
                  80                  85                  90

 Arg Gly Pro Cys Thr Arg Ile Glu Phe Asp Asn Asp Ala Asp Pro
                  95                 100                 105

 Thr Ser Glu Ser Lys Glu Asp Gln Trp Met Gly Val Thr Val Gln
                 110                 115                 120

 Ser Gln Gly Pro Gly Gly Lys Val Val Thr Cys Ala His Arg Tyr
                 125                 130                 135

 Glu Lys Arg Gln His Val Asn Thr Lys Gln Glu Ser Arg Asp Ile
                 140                 145                 150

 Phe Gly Arg Cys Tyr Val Leu Ser Gln Asn Leu Arg Ile Glu Asp
                 155                 160                 165

 Asp Met Asp Gly Gly Asp Trp Ser Phe Cys Asp Gly Arg Leu Arg
                 170                 175                 180

 Gly His Glu Lys Phe Gly Ser Cys Gln Gln Gly Val Ala Ala Thr
                 185                 190                 195

 Phe Thr Lys Asp Phe His Tyr Ile Val Phe Gly Ala Pro Gly Thr
                 200                 205                 210

 Tyr Asn Trp Lys Gly Ile Val Arg Val Glu Gln Lys Asn Asn Thr
                 215                 220                 225

 Phe Phe Asp Met Asn Ile Phe Glu Asp Gly Pro Tyr Glu Val Gly
                 230                 235                 240

 Gly Glu Thr Glu His Asp Glu Ser Leu Val Pro Val Pro Ala Asn
                 245                 250                 255

 Ser Tyr Leu Gly Phe Ser Leu Asp Ser Gly Lys Gly Ile Val Ser
                 260                 265                 270

 Lys Asp Glu Ile Thr Phe Val Ser Gly Ala Pro Arg Ala Asn His
                 275                 280                 285

 Ser Gly Ala Val Val Leu Leu Lys Arg Asp Met Lys Ser Ala His
                 290                 295                 300

 Leu Leu Pro Glu His Ile Phe Asp Gly Glu Gly Leu Ala Ser Ser
                 305                 310                 315

 Phe Gly Tyr Asp Val Ala Val Val Asp Leu Asn Lys Asp Gly Trp
                 320                 325                 330

 Gln Asp Ile Val Ile Gly Ala Pro Gln Tyr Phe Asp Arg Asp Gly
                 335                 340                 345

 Glu Val Gly Gly Ala Val Tyr Val Tyr Met Asn Gln Gln Gly Arg
                 350                 355                 360

 Trp Asn Asn Val Lys Pro Ile Arg Leu Asn Gly Thr Lys Asp Ser
                 365                 370                 375

 Met Phe Gly Ile Ala Val Lys Asn Ile Gly Asp Ile Asn Gln Asp
                 380                 385                 390

 Gly Tyr Pro Asp Ile Ala Val Gly Ala Pro Tyr Asp Asp Leu Gly
                 395                 400                 405

 Lys Val Phe Ile Tyr His Gly Ser Ala Asn Gly Ile Asn Thr Lys
                 410                 415                 420

 Pro Thr Gln Val Leu Lys Gly Ile Ser Pro Tyr Phe Gly Tyr Ser
                 425                 430                 435

 Ile Ala Gly Asn Met Asp Leu Asp Arg Asn Ser Tyr Pro Asp Val
                 440                 445                 450

 Ala Val Gly Ser Leu Ser Asp Ser Val Thr Ile Phe Arg Ser Arg
                 455                 460                 465

 Pro Val Ile Asn Ile Gln Lys Thr Ile Thr Val Thr Pro Asn Arg
                 470                 475                 480

 Ile Asp Leu Arg Gln Lys Thr Ala Cys Gly Ala Pro Ser Gly Ile
                 485                 490                 495

 Cys Leu Gln Val Lys Ser Cys Phe Glu Tyr Thr Ala Asn Pro Ala
                 500                 505                 510

 Gly Tyr Asn Pro Ser Ile Ser Ile Val Gly Thr Leu Glu Ala Glu
                 515                 520                 525

 Lys Glu Arg Arg Lys Ser Gly Leu Ser Ser Arg Val Gln Phe Arg
                 530                 535                 540

 Asn Gln Gly Ser Glu Pro Lys Tyr Thr Gln Glu Leu Thr Leu Lys
                 545                 550                 555

 Arg Gln Lys Gln Lys Val Cys Met Glu Glu Thr Leu Trp Leu Gln
                 560                 565                 570

 Asp Asn Ile Arg Asp Lys Leu Arg Pro Ile Pro Ile Thr Ala Ser
                 575                 580                 585

 Val Glu Ile Gln Glu Pro Ser Ser Arg Arg Arg Val Asn Ser Leu
                 590                 595                 600

 Pro Glu Val Leu Pro Ile Leu Asn Ser Asp Glu Pro Lys Thr Ala
                 605                 610                 615

 His Ile Asp Val His Phe Leu Lys Glu Gly Cys Gly Asp Asp Asn
                 620                 625                 630

 Val Cys Asn Ser Asn Leu Lys Leu Glu Tyr Lys Phe Cys Thr Arg
                 635                 640                 645

 Glu Gly Asn Gln Asp Lys Phe Ser Tyr Leu Pro Ile Gln Lys Gly
                 650                 655                 660

 Val Pro Glu Leu Val Leu Lys Asp Gln Lys Asp Ile Ala Leu Glu
                 665                 670                 675

 Ile Thr Val Thr Asn Ser Pro Ser Asn Pro Arg Asn Pro Thr Lys
                 680                 685                 690

 Asp Gly Asp Asp Ala His Glu Ala Lys Leu Ile Ala Thr Phe Pro
                 695                 700                 705

 Asp Thr Leu Thr Tyr Ser Ala Tyr Arg Glu Leu Arg Ala Phe Pro
                 710                 715                 720

 Glu Lys Gln Leu Ser Cys Val Ala Asn Gln Asn Gly Ser Gln Ala
                 725                 730                 735

 Asp Cys Glu Leu Gly Asn Pro Phe Lys Arg Asn Ser Asn Val Thr
                 740                 745                 750

 Phe Tyr Leu Val Leu Ser Thr Thr Glu Val Thr Phe Asp Thr Pro
                 755                 760                 765

 Tyr Leu Asp Ile Asn Leu Lys Leu Glu Thr Thr Ser Asn Gln Asp
                 770                 775                 780

 Asn Leu Ala Pro Ile Thr Ala Lys Ala Lys Val Val Ile Glu Leu
                 785                 790                 795

 Leu Leu Ser Val Ser Gly Val Ala Lys Pro Ser Gln Val Tyr Phe
                 800                 805                 810

 Gly Gly Thr Val Val Gly Glu Gln Ala Met Lys Ser Glu Asp Glu
                 815                 820                 825

 Val Gly Ser Leu Ile Glu Tyr Glu Phe Arg Val Ile Asn Leu Gly
                 830                 835                 840

 Lys Pro Leu Thr Asn Leu Gly Thr Ala Thr Leu Asn Ile Gln Trp
                 845                 850                 855

 Pro Lys Glu Ile Ser Asn Gly Lys Trp Leu Leu Tyr Leu Val Lys
                 860                 865                 870

 Val Glu Ser Lys Gly Leu Glu Lys Val Thr Cys Glu Pro Gln Lys
                 875                 880                 885

 Glu Ile Asn Ser Leu Asn Leu Thr Glu Ser His Asn Ser Arg Lys
                 890                 895                 900

 Lys Arg Glu Ile Thr Glu Lys Gln Ile Asp Asp Asn Arg Lys Phe
                 905                 910                 915

 Ser Leu Phe Ala Glu Arg Lys Tyr Gln Thr Leu Asn Cys Ser Val
                 920                 925                 930

 Asn Val Asn Cys Val Asn Ile Arg Cys Pro Leu Arg Gly Leu Asp
                 935                 940                 945

 Ser Lys Ala Ser Leu Ile Leu Arg Ser Arg Leu Trp Asn Ser Thr
                 950                 955                 960

 Phe Leu Glu Glu Tyr Ser Lys Leu Asn Tyr Leu Asp Ile Leu Met
                 965                 970                 975

 Arg Ala Phe Ile Asp Val Thr Ala Ala Ala Glu Asn Ile Arg Leu
                 980                 985                 990

 Pro Asn Ala Gly Thr Gln Val Arg Val Thr Val Phe Pro Ser Lys
                 995                1000                1005

 Thr Val Ala Gln Tyr Ser Gly Val Pro Trp Trp Ile Ile Leu Val
                1010                1015                1020

 Ala Ile Leu Ala Gly Ile Leu Met Leu Ala Leu Leu Val Phe Ile
                1025                1030                1035

 Leu Trp Lys Cys Gly Phe Phe Lys Arg Asn Lys Lys Asp His Tyr
                1040                1045                1050

 Asp Ala Thr Tyr His Lys Ala Glu Ile His Ala Gln Pro Ser Asp
                1055                1060                1065

 Lys Glu Arg Leu Thr Ser Asp Ala
                1070

<210> 5272
<211> 2493
<212> DNA
<213> Homo sapien

<400> 5272
 actgcgactc gagacagcgg cccggcagga cagctccaga atgaaaatgc 50

 ggttcttggg gttggtggtc tgtttggttc tctggcccct gcattctgag 100

 gggtctggag ggaaactgac agctgtggat cctgaaacaa acatgaatgt 150

 gagtgaaatt atctcttact ggggattccc tagtgaggaa tacctagttg 200

 agacagaaga tggatatatt ctgtgcctta accgaattcc tcatgggagg 250

 aagaaccatt ctgacaaagg tcccaaacca gttgtcttcc tgcaacatgg 300

 cttgctggca gattctagta actgggtcac aaaccttgcc aacagcagcc 350

 tgggcttcat tcttgctgat gctggttttg acgtgtggat gggcaacagc 400

 agaggaaata cctggtctcg gaaacataag acactctcag tttctcagga 450

 tgaattctgg gctttcagtt atgatgagat ggcaaaatat gacctaccag 500

 cttccattaa cttcattctg aataaaactg gccaagaaca agtgtattat 550

 gtgggtcatt ctcaaggcac cactataggt tttatagcat tttcacagat 600

 ccctgagctg gctaaaagga ttaaaatgtt ttttgccctg ggtcctgtgg 650

 cttccgtcgc cttctgtact agccctatgg ccaaattagg acgattacca 700

 gatcatctca ttaaggactt atttggagac aaagaatttc ttccccagag 750

 tgcgtttttg aagtggctgg gtacccacgt ttgcactcat gtcatactga 800

 aggagctctg tggaaatctc tgttttcttc tgtgtggatt taatgagaga 850

 aatttaaata tgtctagagt ggatgtatat acaacacatt ctcctgctgg 900

 aacttctgtg caaaacatgt tacactggag ccaggctgtt aaattccaaa 950

 agtttcaagc ctttgactgg ggaagcagtg ccaagaatta ttttcattac 1000

 aaccagagtt atcctcccac atacaatgtg aaggacatgc ttgtgccgac 1050

 tgcagtctgg agcgggggtc acgactggct tgcagatgtc tacgacgtca 1100

 atatcttact gactcagatc accaacttgg tgttccatga gagcattccg 1150

 gaatgggagc atcttgactt catttggggc ctggatgccc cttggaggct 1200

 ttataataaa attattaatc taatgaggaa atatcagtga aagctggact 1250

 tgagctgtgt accaccaagt caatgattat gtcatgtgaa aatgtgtttg 1300

 cttcatttct gtaaaacact tgtttttctt tcccaggtct tttgtttttt 1350

 tatatccaag aaaatgataa ctttgaagat gcccagttca ctctagtttc 1400

 aattagaaac atactagcta ttttttcttt aattagggct ggaataggaa 1450

 gccagtgtct caaccatagt attgtctctt taagtctttt aaatatcact 1500

 gatgtgtaaa aaggtcatta tatccattct gtttttaaaa tttaaaatat 1550

 attgactttt tgcccttcat aggacaaagt aatatatgtg ttggaatttt 1600

 aaaattgtgt tgtcattggt aaatctgtca ctgacttaag cgaggtataa 1650

 aagtacgcag ttttcatgtc cttgccttaa agagctctct agtctaacgg 1700

 tcttgtagtt agagatctaa atgacatttt atcatgtttt cctgcagcag 1750

 gtgcatagtc aaatccagaa atatcacagc tgtgccagta ataaggatgc 1800

 taacaattaa ttttatcaaa cctaactgtg acagctgtga tttgacacgt 1850

 tttaattgct caggttaaat gaaatagttt tccggcgtct tcaaaaacaa 1900

 attgcactga taaaacaaaa acaaaagtat gttttaaatg ctttgaagac 1950

 tgatacactc aaccatctat attcatgagc tctcaatttc atggcaggcc 2000

 atagttctac ttatctgaga agcaaatccc tgtggagact ataccactat 2050

 tttttctgag attaatgtac tcttggagcc cgctactgtc gttattgatc 2100

 acatctgtgt gaagccaaag ccccgtggtt gcccatgaga agtgtccttg 2150

 ttcattttca cccaaatgaa gtgtgaacgt gatgttttcg gatgcaaact 2200

 cagctcaggg attcattttg tgtcttagtt ttatatgcat ccttattttt 2250

 aatacacctg cttcacgtcc ctatgttggg aagtccatat ttgtctgctt 2300

 ttcttgcagc atcatttcct tacaatactg tccggtggac aaaatgacaa 2350

 ttgatatgtt tttctgatat aattacttta gctgcactaa cagtacaatg 2400

 cttgttaatg gttaatatag gcagggcgaa tactactttg taacttttaa 2450

 agtcttaaac ttttcaataa aattgagtga gacttatagg ccc 2493

<210> 5273
<211> 399
<212> PRT
<213> Homo sapien

<400> 5273
 Met Lys Met Arg Phe Leu Gly Leu Val Val Cys Leu Val Leu Trp
   1               5                  10                  15

 Pro Leu His Ser Glu Gly Ser Gly Gly Lys Leu Thr Ala Val Asp
                  20                  25                  30

 Pro Glu Thr Asn Met Asn Val Ser Glu Ile Ile Ser Tyr Trp Gly
                  35                  40                  45

 Phe Pro Ser Glu Glu Tyr Leu Val Glu Thr Glu Asp Gly Tyr Ile
                  50                  55                  60

 Leu Cys Leu Asn Arg Ile Pro His Gly Arg Lys Asn His Ser Asp
                  65                  70                  75

 Lys Gly Pro Lys Pro Val Val Phe Leu Gln His Gly Leu Leu Ala
                  80                  85                  90

 Asp Ser Ser Asn Trp Val Thr Asn Leu Ala Asn Ser Ser Leu Gly
                  95                 100                 105

 Phe Ile Leu Ala Asp Ala Gly Phe Asp Val Trp Met Gly Asn Ser
                 110                 115                 120

 Arg Gly Asn Thr Trp Ser Arg Lys His Lys Thr Leu Ser Val Ser
                 125                 130                 135

 Gln Asp Glu Phe Trp Ala Phe Ser Tyr Asp Glu Met Ala Lys Tyr
                 140                 145                 150

 Asp Leu Pro Ala Ser Ile Asn Phe Ile Leu Asn Lys Thr Gly Gln
                 155                 160                 165

 Glu Gln Val Tyr Tyr Val Gly His Ser Gln Gly Thr Thr Ile Gly
                 170                 175                 180

 Phe Ile Ala Phe Ser Gln Ile Pro Glu Leu Ala Lys Arg Ile Lys
                 185                 190                 195

 Met Phe Phe Ala Leu Gly Pro Val Ala Ser Val Ala Phe Cys Thr
                 200                 205                 210

 Ser Pro Met Ala Lys Leu Gly Arg Leu Pro Asp His Leu Ile Lys
                 215                 220                 225

 Asp Leu Phe Gly Asp Lys Glu Phe Leu Pro Gln Ser Ala Phe Leu
                 230                 235                 240

 Lys Trp Leu Gly Thr His Val Cys Thr His Val Ile Leu Lys Glu
                 245                 250                 255

 Leu Cys Gly Asn Leu Cys Phe Leu Leu Cys Gly Phe Asn Glu Arg
                 260                 265                 270

 Asn Leu Asn Met Ser Arg Val Asp Val Tyr Thr Thr His Ser Pro
                 275                 280                 285

 Ala Gly Thr Ser Val Gln Asn Met Leu His Trp Ser Gln Ala Val
                 290                 295                 300

 Lys Phe Gln Lys Phe Gln Ala Phe Asp Trp Gly Ser Ser Ala Lys
                 305                 310                 315

 Asn Tyr Phe His Tyr Asn Gln Ser Tyr Pro Pro Thr Tyr Asn Val
                 320                 325                 330

 Lys Asp Met Leu Val Pro Thr Ala Val Trp Ser Gly Gly His Asp
                 335                 340                 345

 Trp Leu Ala Asp Val Tyr Asp Val Asn Ile Leu Leu Thr Gln Ile
                 350                 355                 360

 Thr Asn Leu Val Phe His Glu Ser Ile Pro Glu Trp Glu His Leu
                 365                 370                 375

 Asp Phe Ile Trp Gly Leu Asp Ala Pro Trp Arg Leu Tyr Asn Lys
                 380                 385                 390

 Ile Ile Asn Leu Met Arg Lys Tyr Gln
                 395

<210> 5274
<211> 1487
<212> DNA
<213> Homo sapien

<400> 5274
 ctagcactct gacctagcag tcaacatgaa ggctctcatt gttctggggc 50

 ttgtcctcct ttctgttacg gtccagggca aggtctttga aaggtgtgag 100

 ttggccagaa ctctgaaaag attgggaatg gatggctaca ggggaatcag 150

 cctagcaaac tggatgtgtt tggccaaatg ggagagtggt tacaacacac 200

 gagctacaaa ctacaatgct ggagacagaa gcactgatta tgggatattt 250

 cagatcaata gccgctactg gtgtaatgat ggcaaaaccc caggagcagt 300

 taatgcctgt catttatcct gcagtgcttt gctgcaagat aacatcgctg 350

 atgctgtagc ttgtgcaaag agggttgtcc gtgatccaca aggcattaga 400

 gcatgggtgg catggagaaa tcgttgtcaa aacagagatg tccgtcagta 450

 tgttcaaggt tgtggagtgt aactccagaa ttttccttct tcagctcatt 500

 ttgtctctct cacattaagg gagtaggaat taagtgaaag gtcacactac 550

 cattatttcc ccttcaaaca aataatattt ttacagaagc aggagcaaaa 600

 tatggccttt cttctaagag atataatgtt cactaatgtg gttattttac 650

 attaagccta caacattttt cagtttgcaa atagaactaa tactggtgaa 700

 aatttaccta aaaccttggt tatcaaatac atctccagta cattccgttc 750

 tttttttttt ttgagacagt ctcgctctgt cgcccaggct ggagtgcagt 800

 ggcgcaatct cggctcactg caacctccac ctcccgggtt cacgccattc 850

 tcctgcctca gcctcccgag tagctgggat tacgggcgcc cgccaccacg 900

 cccggctaat tttttgtatt tttagtagag acagggtttc accgtgttag 950

 ccaggatggt ctcgatctcc tgaccttgtg atccacccac ctcggcctcc 1000

 caaagtgctg ggattacagg cgtgagccac tgcgcccggc cacattcagt 1050

 tcttatcaaa gaaataaccc agacttaatc ttgaatgata cgattatgcc 1100

 caatattaag taaaaaatat aagaaaaggt tatcttaaat agatcttagg 1150

 caaaatacca gctgatgaag gcatctgatg ccttcatctg ttcagtcatc 1200

 tccaaaaaca gtaaaaataa ccactttttg ttgggcaata tgaaattttt 1250

 aaaggagtag aataccaaat gatagaaaca gactgcctga attgagaatt 1300

 ttgatttctt aaagtgtgtt tctttctaaa ttgctgttcc ttaatttgat 1350

 taatttaatt catgtattat gattaaatct gaggcagatg agcttacaag 1400

 tattgaaata attactaatt aatcacaaat gtgaagttat gcatgatgta 1450

 aaaaatacaa acattctaat taaaggcttt gcaacac 1487

<210> 5275
<211> 148
<212> PRT
<213> Homo sapien

<400> 5275
 Met Lys Ala Leu Ile Val Leu Gly Leu Val Leu Leu Ser Val Thr
   1               5                  10                  15

 Val Gln Gly Lys Val Phe Glu Arg Cys Glu Leu Ala Arg Thr Leu
                  20                  25                  30

 Lys Arg Leu Gly Met Asp Gly Tyr Arg Gly Ile Ser Leu Ala Asn
                  35                  40                  45

 Trp Met Cys Leu Ala Lys Trp Glu Ser Gly Tyr Asn Thr Arg Ala
                  50                  55                  60

 Thr Asn Tyr Asn Ala Gly Asp Arg Ser Thr Asp Tyr Gly Ile Phe
                  65                  70                  75

 Gln Ile Asn Ser Arg Tyr Trp Cys Asn Asp Gly Lys Thr Pro Gly
                  80                  85                  90

 Ala Val Asn Ala Cys His Leu Ser Cys Ser Ala Leu Leu Gln Asp
                  95                 100                 105

 Asn Ile Ala Asp Ala Val Ala Cys Ala Lys Arg Val Val Arg Asp
                 110                 115                 120

 Pro Gln Gly Ile Arg Ala Trp Val Ala Trp Arg Asn Arg Cys Gln
                 125                 130                 135

 Asn Arg Asp Val Arg Gln Tyr Val Gln Gly Cys Gly Val
                 140                 145

<210> 5276
<211> 732
<212> DNA
<213> Homo sapien

<400> 5276
 tgctgcgaac cacgtgggtc ccgggcgcgt ttcgggtgct ggcggctgca 50

 gccggagttc aaacctaagc agctggaagg aaccatggcc aactgtgagc 100

 gtaccttcat tgcgatcaaa ccagatgggg tccagcgggg tcttgtggga 150

 gagattatca agcgttttga gcagaaagga ttccgccttg ttggtctgaa 200

 attcatgcaa gcttccgaag atcttctcaa ggaacactac gttgacctga 250

 aggaccgtcc attctttgcc ggcctggtga aatacatgca ctcagggccg 300

 gtagttgcca tggtctggga ggggctgaat gtggtgaaga cgggccgagt 350

 catgctcggg gagaccaacc ctgcagactc caagcctggg accatccgtg 400

 gagacttctg catacaagtt ggcaggaaca ttatacatgg cagtgattct 450

 gtggagagtg cagagaagga gatcggcttg tggtttcacc ctgaggaact 500

 ggtagattac acgagctgtg ctcagaactg gatctatgaa tgacaggagg 550

 gcagaccaca ttgcttttca catccatttc ccctccttcc catgggcaga 600

 ggaccaggct gtaggaaatc tagttattta caggaacttc atcataattt 650

 ggagggaagc tcttggagct gtgagttctc cctgtacagt gttaccatcc 700

 ccgaccatct gattaaaatg cttcctccca gc 732

<210> 5277
<211> 152
<212> PRT
<213> Homo sapien

<400> 5277
 Met Ala Asn Cys Glu Arg Thr Phe Ile Ala Ile Lys Pro Asp Gly
   1               5                  10                  15

 Val Gln Arg Gly Leu Val Gly Glu Ile Ile Lys Arg Phe Glu Gln
                  20                  25                  30

 Lys Gly Phe Arg Leu Val Gly Leu Lys Phe Met Gln Ala Ser Glu
                  35                  40                  45

 Asp Leu Leu Lys Glu His Tyr Val Asp Leu Lys Asp Arg Pro Phe
                  50                  55                  60

 Phe Ala Gly Leu Val Lys Tyr Met His Ser Gly Pro Val Val Ala
                  65                  70                  75

 Met Val Trp Glu Gly Leu Asn Val Val Lys Thr Gly Arg Val Met
                  80                  85                  90

 Leu Gly Glu Thr Asn Pro Ala Asp Ser Lys Pro Gly Thr Ile Arg
                  95                 100                 105

 Gly Asp Phe Cys Ile Gln Val Gly Arg Asn Ile Ile His Gly Ser
                 110                 115                 120

 Asp Ser Val Glu Ser Ala Glu Lys Glu Ile Gly Leu Trp Phe His
                 125                 130                 135

 Pro Glu Glu Leu Val Asp Tyr Thr Ser Cys Ala Gln Asn Trp Ile
                 140                 145                 150

 Tyr Glu


<210> 5278
<211> 1600
<212> DNA
<213> Homo sapien

<400> 5278
 cggagcgagg cagcgcgccc ggctcccgcg ccatggggcg gctggtggct 50

 gtgggcttgc tggggatcgc gctggcgctc ctgggcgaga ggcttctggc 100

 actcagaaat cgacttaaag cctccagaga agtagaatct gtagaccttc 150

 cacactgcca cctgattaaa ggaattgaag ctggctctga agatattgac 200

 atacttccca atggtctggc tttttttagt gtgggtctaa aattcccagg 250

 actccacagc tttgcaccag ataagcctgg aggaatacta atgatggatc 300

 taaaagaaga aaaaccaagg gcacgggaat taagaatcag tcgtgggttt 350

 gatttggcct cattcaatcc acatggcatc agcactttca tagacaacga 400

 tgacacagtt tatctctttg ttgtaaacca cccagaattc aagaatacag 450

 tggaaatttt taaatttgaa gaagcagaaa attctctgtt gcatctgaaa 500

 acagtcaaac atgagcttct tccaagtgtg aatgacatca cagctgttgg 550

 accggcacat ttctatgcca caaatgacca ctacttctct gatcctttct 600

 taaagtattt agaaacatac ttgaacttac actgggcaaa tgttgtttac 650

 tacagtccaa atgaagttaa agtggtagca gaaggatttg attcagcaaa 700

 tgggatcaat atttcacctg atgataagta tatctatgtt gctgacatat 750

 tggctcatga aattcatgtt ttggaaaaac acactaatat gaatttaact 800

 cagttgaagg tacttgagct ggatacactg gtggataatt tatctattga 850

 tccttcctcg ggggacatct gggtagtctg tcatcctaat ggccagaagc 900

 tcttcgtgta tgacccgaac aatcctccct cgtcagaggt tctccgcatc 950

 cagaacattc tatctgagaa gcctacagtg actacagttt atgccaacaa 1000

 tgggtctgtt ctccaaggaa gttctgtagc ctcagtgtat gatgggaagc 1050

 tgctcatagg cactttatac cacagagcct tgtattgtga actctaaatt 1100

 gtacttttgg catgaaagtg cgataactta acaattaatt ttctatgaaa 1150

 ttgctaattc tgagggaatt taaccagcaa cattgaccca gaaatgtatg 1200

 gcatgtgtag ttaattttat tccagtaagg aacggccctt ttagttctta 1250

 gagcactttt aacaaaaaag gaaaatgaac aggttcttta aaatgccaag 1300

 caagggacag aaaagaaagc tgctttcgaa taaagtgaat acattttgca 1350

 caaagtaagc ctcacctttg ccttccaact gccagaacat ggattccact 1400

 gaaatagagt gaattatatt tccttaaaat gtgagtgacc tcacttctgg 1450

 cactgtgact actatggctg tttagaacta ctgataataa cgtattttga 1500

 tgttttgtac ttacatcttt gtttaccatt aaaaagttgg agttatatta 1550

 aagactaact aaaatcccaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1600

<210> 5279
<211> 354
<212> PRT
<213> Homo sapien

<400> 5279
 Met Gly Arg Leu Val Ala Val Gly Leu Leu Gly Ile Ala Leu Ala
   1               5                  10                  15

 Leu Leu Gly Glu Arg Leu Leu Ala Leu Arg Asn Arg Leu Lys Ala
                  20                  25                  30

 Ser Arg Glu Val Glu Ser Val Asp Leu Pro His Cys His Leu Ile
                  35                  40                  45

 Lys Gly Ile Glu Ala Gly Ser Glu Asp Ile Asp Ile Leu Pro Asn
                  50                  55                  60

 Gly Leu Ala Phe Phe Ser Val Gly Leu Lys Phe Pro Gly Leu His
                  65                  70                  75

 Ser Phe Ala Pro Asp Lys Pro Gly Gly Ile Leu Met Met Asp Leu
                  80                  85                  90

 Lys Glu Glu Lys Pro Arg Ala Arg Glu Leu Arg Ile Ser Arg Gly
                  95                 100                 105

 Phe Asp Leu Ala Ser Phe Asn Pro His Gly Ile Ser Thr Phe Ile
                 110                 115                 120

 Asp Asn Asp Asp Thr Val Tyr Leu Phe Val Val Asn His Pro Glu
                 125                 130                 135

 Phe Lys Asn Thr Val Glu Ile Phe Lys Phe Glu Glu Ala Glu Asn
                 140                 145                 150

 Ser Leu Leu His Leu Lys Thr Val Lys His Glu Leu Leu Pro Ser
                 155                 160                 165

 Val Asn Asp Ile Thr Ala Val Gly Pro Ala His Phe Tyr Ala Thr
                 170                 175                 180

 Asn Asp His Tyr Phe Ser Asp Pro Phe Leu Lys Tyr Leu Glu Thr
                 185                 190                 195

 Tyr Leu Asn Leu His Trp Ala Asn Val Val Tyr Tyr Ser Pro Asn
                 200                 205                 210

 Glu Val Lys Val Val Ala Glu Gly Phe Asp Ser Ala Asn Gly Ile
                 215                 220                 225

 Asn Ile Ser Pro Asp Asp Lys Tyr Ile Tyr Val Ala Asp Ile Leu
                 230                 235                 240

 Ala His Glu Ile His Val Leu Glu Lys His Thr Asn Met Asn Leu
                 245                 250                 255

 Thr Gln Leu Lys Val Leu Glu Leu Asp Thr Leu Val Asp Asn Leu
                 260                 265                 270

 Ser Ile Asp Pro Ser Ser Gly Asp Ile Trp Val Val Cys His Pro
                 275                 280                 285

 Asn Gly Gln Lys Leu Phe Val Tyr Asp Pro Asn Asn Pro Pro Ser
                 290                 295                 300

 Ser Glu Val Leu Arg Ile Gln Asn Ile Leu Ser Glu Lys Pro Thr
                 305                 310                 315

 Val Thr Thr Val Tyr Ala Asn Asn Gly Ser Val Leu Gln Gly Ser
                 320                 325                 330

 Ser Val Ala Ser Val Tyr Asp Gly Lys Leu Leu Ile Gly Thr Leu
                 335                 340                 345

 Tyr His Arg Ala Leu Tyr Cys Glu Leu
                 350

<210> 5280
<211> 2279
<212> DNA
<213> Homo sapien

<400> 5280
 ggcacgagcg aagatggcgt cgcccggctg cctgtggctc ttggctgtgg 50

 ctctcctgcc atggacctgc gcttctcggg cgctgcagca tctggacccg 100

 ccggcgccgc tgccgttggt gatctggcat gggatgggag acagctgttg 150

 caatccctta agcatgggtg ctattaaaaa aatggtggag aagaaaatac 200

 ctggaattta cgtcttatct ttagagattg ggaagaccct gatggaggac 250

 gtggagaaca gcttcttctt gaatgtcaat tcccaagtaa caacagtgtg 300

 tcaggcactt gctaaggatc ctaaattgca gcaaggctac aatgctatgg 350

 gattctccca gggaggccaa tttctgaggg cagtggctca gagatgccct 400

 tcacctccca tgatcaatct gatctcggtt gggggacaac atcaaggtgt 450

 ttttggactc cctcgatgcc caggagagag ctctcacatc tgtgacttca 500

 tccgaaaaac actgaatgct ggggcgtact ccaaagttgt tcaggaacgc 550

 ctcgtgcaag ccgaatactg gcatgacccc ataaaggagg atgtgtatcg 600

 caaccacagc atcttcttgg cagatataaa tcaggagcgg ggtatcaatg 650

 agtcctacaa gaaaaacctg atggccctga agaagtttgt gatggtgaaa 700

 ttcctcaatg attccattgt ggaccctgta gattcggagt ggtttggatt 750

 ttacagaagt ggccaagcca aggaaaccat tcccttacag gagacctccc 800

 tgtacacaca ggaccgcctg gggctaaagg aaatggacaa tgcaggacag 850

 ctagtgtttc tggctacaga aggggaccat cttcagttgt ctgaagaatg 900

 gttttatgcc cacatcatac cattccttgg atgaaacccg tatagttcac 950

 aatagagctc agggagcccc taactcttcc aaaccacatg ggagacagtt 1000

 tccttcatgc ccaagcctga gctcagatcc agcttgcaac taatccttct 1050

 atcatctaac atgcactact tggaaagatc taagatctga atcttatcct 1100

 ttgccatctt ctgttaccat atggtgttga atgcaagttt aattaccatg 1150

 gagattgttt tacaaacttt tgatgtggtc aagttcagtt ttagaaaagg 1200

 gagtctgttc cagatcaggg ccagaactgt gcccaggccc aaaggagaca 1250

 actaactaaa gtagtgagat agattctaag ggcaaacatt tttccaagtc 1300

 ttgccatatt tcaagcaaag aggtgcccag gcctgaggta ctcacataaa 1350

 tgctttgttt tgctggtgat ttaaccagtg cttggaaaaa tcttgcttgg 1400

 ctatttctgc atcatttctt aaggctgcct tcctctctga gtacgttgcc 1450

 ctctgtgcta tcaatcatct tatcatcaat tattagacaa atcccactgg 1500

 cctacagtct tgcttctgca gcacccactt tgtctcctca ggtagtgatg 1550

 aattagttgc tgtcacaaaa ggagggaagt agcacccaaa ttaaattgct 1600

 taagagagga aatgtacatc ttgtataact tagggagcga agaaaatgta 1650

 ggcgcgaaag tgaaaagtga ggcagctagt tcttcctatt ccattctcga 1700

 ccaacctgcc ctttcttaat atgactagtg gtcttgatgc tagagtcaac 1750

 ttactctgtt gctggcttta gcagagaata ggaggaacca tatgaaaaag 1800

 atcaggcttt ctgacttcca tccccaaaac acatttacca gcatactcca 1850

 aactgtttct gatgtgttcc atgagaaaag gattgtttgc tcaaaaagct 1900

 tggaaaatac tacacactcc ctttctcctt ctggagatca acccacatta 1950

 gagtgtctaa ggactcctga gaattcctgt tacagtaaac aaaactaacg 2000

 taatctacca tttcctacac tatttgagca tggaaatcat agtccccact 2050

 ctatgaaaac ttaacgcttt ttggaagaca tttctgtagc atgtcagttt 2100

 ggagaaatga tgagctacgc cttgatgaaa gaaccgtgtt ggtgctgcta 2150

 agtttagcca ttatggtttt tcctttctct ctcttaagcc ttattcttca 2200

 actaaaagat gaggattaag agcaagaagt tgggggggat gtgaaaataa 2250

 ttttatgagg ttgtctaaaa tctcgtgcc 2279

<210> 5281
<211> 306
<212> PRT
<213> Homo sapien

<400> 5281
 Met Ala Ser Pro Gly Cys Leu Trp Leu Leu Ala Val Ala Leu Leu
   1               5                  10                  15

 Pro Trp Thr Cys Ala Ser Arg Ala Leu Gln His Leu Asp Pro Pro
                  20                  25                  30

 Ala Pro Leu Pro Leu Val Ile Trp His Gly Met Gly Asp Ser Cys
                  35                  40                  45

 Cys Asn Pro Leu Ser Met Gly Ala Ile Lys Lys Met Val Glu Lys
                  50                  55                  60

 Lys Ile Pro Gly Ile Tyr Val Leu Ser Leu Glu Ile Gly Lys Thr
                  65                  70                  75

 Leu Met Glu Asp Val Glu Asn Ser Phe Phe Leu Asn Val Asn Ser
                  80                  85                  90

 Gln Val Thr Thr Val Cys Gln Ala Leu Ala Lys Asp Pro Lys Leu
                  95                 100                 105

 Gln Gln Gly Tyr Asn Ala Met Gly Phe Ser Gln Gly Gly Gln Phe
                 110                 115                 120

 Leu Arg Ala Val Ala Gln Arg Cys Pro Ser Pro Pro Met Ile Asn
                 125                 130                 135

 Leu Ile Ser Val Gly Gly Gln His Gln Gly Val Phe Gly Leu Pro
                 140                 145                 150

 Arg Cys Pro Gly Glu Ser Ser His Ile Cys Asp Phe Ile Arg Lys
                 155                 160                 165

 Thr Leu Asn Ala Gly Ala Tyr Ser Lys Val Val Gln Glu Arg Leu
                 170                 175                 180

 Val Gln Ala Glu Tyr Trp His Asp Pro Ile Lys Glu Asp Val Tyr
                 185                 190                 195

 Arg Asn His Ser Ile Phe Leu Ala Asp Ile Asn Gln Glu Arg Gly
                 200                 205                 210

 Ile Asn Glu Ser Tyr Lys Lys Asn Leu Met Ala Leu Lys Lys Phe
                 215                 220                 225

 Val Met Val Lys Phe Leu Asn Asp Ser Ile Val Asp Pro Val Asp
                 230                 235                 240

 Ser Glu Trp Phe Gly Phe Tyr Arg Ser Gly Gln Ala Lys Glu Thr
                 245                 250                 255

 Ile Pro Leu Gln Glu Thr Ser Leu Tyr Thr Gln Asp Arg Leu Gly
                 260                 265                 270

 Leu Lys Glu Met Asp Asn Ala Gly Gln Leu Val Phe Leu Ala Thr
                 275                 280                 285

 Glu Gly Asp His Leu Gln Leu Ser Glu Glu Trp Phe Tyr Ala His
                 290                 295                 300

 Ile Ile Pro Phe Leu Gly
                 305

<210> 5282
<211> 4740
<212> DNA
<213> Homo sapien

<400> 5282
 ttccggtttt tctcagggga cgttgaaatt atttttgtaa cgggagtcgg 50

 gagaggacgg ggcgtgcccc gcgtgcgcgc gcgtcgtcct ccccggcgct 100

 cctccacagc tcgctggctc ccgccgcgga aaggcgtcat gccgcccaaa 150

 accccccgaa aaacggccgc caccgccgcc gctgccgccg cggaaccccc 200

 ggcaccgccg ccgccgcccc ctcctgagga ggacccagag caggacagcg 250

 gcccggagga cctgcctctc gtcaggcttg agtttgaaga aacagaagaa 300

 cctgatttta ctgcattatg tcagaaatta aagataccag atcatgtcag 350

 agagagagct tggttaactt gggagaaagt ttcatctgtg gatggagtat 400

 tgggaggtta tattcaaaag aaaaaggaac tgtggggaat ctgtatcttt 450

 attgcacgag ttgacctaga tgagatgtcg ttcactttac tgagctacag 500

 aaaaacatac gaaatcagtg tccataaatt ctttaactta ctaaaagaaa 550

 ttgataccag taccaaagtt gataatgcta tgtcaagact gttgaagaag 600

 tatgatgtat tgtttgcact cttcagcaaa ttggaaagga catgtgaact 650

 tatatatttg acacaaccca gcagttcgat atctactgaa ataaattctg 700

 cattggtgct aaaagtttct tggatcacat ttttattagc taaaggggaa 750

 gtattacaaa tggaagatga tctggtgatt tcatttcagt taatgctatg 800

 tgtccttgac tattttatta aactctcacc tcccatgttg ctcaaagaac 850

 catataaaac agctgttata cccattaatg gttcacctcg aacacccagg 900

 cgaggtcaga acaggagtgc acggatagca aaacaactag aaaatgatac 950

 aagaattatt gaagttctct gtaaagaaca tgaatgtaat atagatgagg 1000

 tgaaaaatgt ttatttcaaa aattttatac cttttatgaa ttctcttgga 1050

 cttgtaacat ctaatggact tccagaggtt gaaaatcttt ctaaacgata 1100

 cgaagaaatt tatcttaaaa ataaagatct agatcgaaga ttatttttgg 1150

 atcatgataa aactcttcag actgattcta tagacagttt tgaaacacag 1200

 agaacaccac gaaaaagtaa ccttgatgaa gaggtgaata taattcctcc 1250

 acacactcca gttaggactg ttatgaacac tatccaacaa ttaatgatga 1300

 ttttaaattc tgcaagtgat caaccttcag aaaatctgat ttcctatttt 1350

 aacaactgca cagtgaatcc aaaagaaagt atactgaaaa gagtgaagga 1400

 tataggatac atctttaaag agaaatttgc taaagctgtg ggacagggtt 1450

 gtgtcgaaat tggatcacag cgatacaaac ttggagttcg cttgtattac 1500

 cgagtaatgg aatccatgct taaatcagaa gaagaacgat tatccattca 1550

 aaattttagc aaacttctga atgacaacat ttttcatatg tctttattgg 1600

 cgtgcgctct tgaggttgta atggccacat atagcagaag tacatctcag 1650

 aatcttgatt ctggaacaga tttgtctttc ccatggattc tgaatgtgct 1700

 taatttaaaa gcctttgatt tttacaaagt gatcgaaagt tttatcaaag 1750

 cagaaggcaa cttgacaaga gaaatgataa aacatttaga acgatgtgaa 1800

 catcgaatca tggaatccct tgcatggctc tcagattcac ctttatttga 1850

 tcttattaaa caatcaaagg accgagaagg accaactgat caccttgaat 1900

 ctgcttgtcc tcttaatctt cctctccaga ataatcacac tgcagcagat 1950

 atgtatcttt ctcctgtaag atctccaaag aaaaaaggtt caactacgcg 2000

 tgtaaattct actgcaaatg cagagacaca agcaacctca gccttccaga 2050

 cccagaagcc attgaaatct acctctcttt cactgtttta taaaaaagtg 2100

 tatcggctag cctatctccg gctaaataca ctttgtgaac gccttctgtc 2150

 tgagcaccca gaattagaac atatcatctg gacccttttc cagcacaccc 2200

 tgcagaatga gtatgaactc atgagagaca ggcatttgga ccaaattatg 2250

 atgtgttcca tgtatggcat atgcaaagtg aagaatatag accttaaatt 2300

 caaaatcatt gtaacagcat acaaggatct tcctcatgct gttcaggaga 2350

 cattcaaacg tgttttgatc aaagaagagg agtatgattc tattatagta 2400

 ttctataact cggtcttcat gcagagactg aaaacaaata ttttgcagta 2450

 tgcttccacc aggcccccta ccttgtcacc aatacctcac attcctcgaa 2500

 gcccttacaa gtttcctagt tcacccttac ggattcctgg agggaacatc 2550

 tatatttcac ccctgaagag tccatataaa atttcagaag gtctgccaac 2600

 accaacaaaa atgactccaa gatcaagaat cttagtatca attggtgaat 2650

 cattcgggac ttctgagaag ttccagaaaa taaatcagat ggtatgtaac 2700

 agcgaccgtg tgctcaaaag aagtgctgaa ggaagcaacc ctcctaaacc 2750

 actgaaaaaa ctacgctttg atattgaagg atcagatgaa gcagatggaa 2800

 gtaaacatct cccaggagag tccaaatttc agcagaaact ggcagaaatg 2850

 acttctactc gaacacgaat gcaaaagcag aaaatgaatg atagcatgga 2900

 tacctcaaac aaggaagaga aatgaggatc tcaggacctt ggtggacact 2950

 gtgtacacct ctggattcat tgtctctcac agatgtgact gtataacttt 3000

 cccaggttct gtttatggcc acatttaata tcttcagctc tttttgtgga 3050

 tataaaatgt gcagatgcaa ttgtttgggt gagtcctaag ccacttgaaa 3100

 tgttagtcat tgttatttat acaagattga aaatcttgtg taaatcctgc 3150

 catttaaaaa gttgtagcag attgtttcct cttccaaagt aaaattgctg 3200

 tgctttatgg atagtaagaa tggccctaga gtgggagtcc tgataaccca 3250

 ggcctgtctg actactttgc cttcttttgt agcatatagg tgatgtttgc 3300

 tcttgttttt attaatttat atgtatattt ttttaattta acatgaacac 3350

 ccttagaaaa tgtgtcctat ctatcttcca aatgcaattt gattgactgc 3400

 ccattcacca aaattatcct gaactcttct gcaaaaatgg atattattag 3450

 aaattagaaa aaaattacta attttacaca ttagatttta ttttactatt 3500

 ggaatctgat atactgtgtg cttgttttat aaaattttgc ttttaattaa 3550

 ataaaagctg gaagcaaagt ataaccatat gatactatca tactactgaa 3600

 acagatttca tacctcagaa tgtaaaagaa cttactgatt attttcttca 3650

 tccaacttat gtttttaaat gaggattatt gatagtactc ttggttttta 3700

 taccattcag atcactgaat ttataaagta cccatctagt acttgaaaaa 3750

 gtaaagtgtt ctgccagatc ttaggtatag aggaccctaa cacagtatat 3800

 cccaagtgca ctttctaatg tttctgggtc ctgaagaatt aagatacaaa 3850

 ttaattttac tccataaaca gactgttaat tataggagcc ttaatttttt 3900

 tttcatagag atttgtctaa ttgcatctca aaattattct gccctcctta 3950

 atttgggaag gtttgtgttt tctctggaat ggtacatgtc ttccatgtat 4000

 cttttgaact ggcaattgtc tatttatctt ttattttttt aagtcagtat 4050

 ggtctaacac tggcatgttc aaagccacat tatttctagt ccaaaattac 4100

 aagtaatcaa gggtcattat gggttaggca ttaatgtttc tatctgattt 4150

 tgtgcaaaag cttcaaatta aaacagctgc attagaaaaa gaggcgcttc 4200

 tcccctcccc tacacctaaa ggtgtattta aactatcttg tgtgattaac 4250

 ttatttagag atgctgtaac ttaaaatagg ggatatttaa ggtagcttca 4300

 gctagctttt aggaaaatca ctttgtctaa ctcagaatta tttttaaaaa 4350

 gaaatctggt cttgttagaa aacaaaattt tattttgtgc tcatttaagt 4400

 ttcaaactta ctattttgac agttattttg ataacaatga cactagaaaa 4450

 cttgactcca tttcatcatt gtttctgcat gaatatcata caaatcagtt 4500

 agtttttagg tcaagggctt actatttctg ggtcttttgc tactaagttc 4550

 acattagaat tagtgccaga attttaggaa cttcagagat cgtgtattga 4600

 gatttcttaa ataatgcttc agatattatt gctttattgc ttttttgtat 4650

 tggttaaaac tgtacattta aaattgctat gttactattt tctacaatta 4700

 atagtttgtc tattttaaaa taaattagtt gttaagagtc 4740

<210> 5283
<211> 928
<212> PRT
<213> Homo sapien

<400> 5283
 Met Pro Pro Lys Thr Pro Arg Lys Thr Ala Ala Thr Ala Ala Ala
   1               5                  10                  15

 Ala Ala Ala Glu Pro Pro Ala Pro Pro Pro Pro Pro Pro Pro Glu
                  20                  25                  30

 Glu Asp Pro Glu Gln Asp Ser Gly Pro Glu Asp Leu Pro Leu Val
                  35                  40                  45

 Arg Leu Glu Phe Glu Glu Thr Glu Glu Pro Asp Phe Thr Ala Leu
                  50                  55                  60

 Cys Gln Lys Leu Lys Ile Pro Asp His Val Arg Glu Arg Ala Trp
                  65                  70                  75

 Leu Thr Trp Glu Lys Val Ser Ser Val Asp Gly Val Leu Gly Gly
                  80                  85                  90

 Tyr Ile Gln Lys Lys Lys Glu Leu Trp Gly Ile Cys Ile Phe Ile
                  95                 100                 105

 Ala Arg Val Asp Leu Asp Glu Met Ser Phe Thr Leu Leu Ser Tyr
                 110                 115                 120

 Arg Lys Thr Tyr Glu Ile Ser Val His Lys Phe Phe Asn Leu Leu
                 125                 130                 135

 Lys Glu Ile Asp Thr Ser Thr Lys Val Asp Asn Ala Met Ser Arg
                 140                 145                 150

 Leu Leu Lys Lys Tyr Asp Val Leu Phe Ala Leu Phe Ser Lys Leu
                 155                 160                 165

 Glu Arg Thr Cys Glu Leu Ile Tyr Leu Thr Gln Pro Ser Ser Ser
                 170                 175                 180

 Ile Ser Thr Glu Ile Asn Ser Ala Leu Val Leu Lys Val Ser Trp
                 185                 190                 195

 Ile Thr Phe Leu Leu Ala Lys Gly Glu Val Leu Gln Met Glu Asp
                 200                 205                 210

 Asp Leu Val Ile Ser Phe Gln Leu Met Leu Cys Val Leu Asp Tyr
                 215                 220                 225

 Phe Ile Lys Leu Ser Pro Pro Met Leu Leu Lys Glu Pro Tyr Lys
                 230                 235                 240

 Thr Ala Val Ile Pro Ile Asn Gly Ser Pro Arg Thr Pro Arg Arg
                 245                 250                 255

 Gly Gln Asn Arg Ser Ala Arg Ile Ala Lys Gln Leu Glu Asn Asp
                 260                 265                 270

 Thr Arg Ile Ile Glu Val Leu Cys Lys Glu His Glu Cys Asn Ile
                 275                 280                 285

 Asp Glu Val Lys Asn Val Tyr Phe Lys Asn Phe Ile Pro Phe Met
                 290                 295                 300

 Asn Ser Leu Gly Leu Val Thr Ser Asn Gly Leu Pro Glu Val Glu
                 305                 310                 315

 Asn Leu Ser Lys Arg Tyr Glu Glu Ile Tyr Leu Lys Asn Lys Asp
                 320                 325                 330

 Leu Asp Arg Arg Leu Phe Leu Asp His Asp Lys Thr Leu Gln Thr
                 335                 340                 345

 Asp Ser Ile Asp Ser Phe Glu Thr Gln Arg Thr Pro Arg Lys Ser
                 350                 355                 360

 Asn Leu Asp Glu Glu Val Asn Ile Ile Pro Pro His Thr Pro Val
                 365                 370                 375

 Arg Thr Val Met Asn Thr Ile Gln Gln Leu Met Met Ile Leu Asn
                 380                 385                 390

 Ser Ala Ser Asp Gln Pro Ser Glu Asn Leu Ile Ser Tyr Phe Asn
                 395                 400                 405

 Asn Cys Thr Val Asn Pro Lys Glu Ser Ile Leu Lys Arg Val Lys
                 410                 415                 420

 Asp Ile Gly Tyr Ile Phe Lys Glu Lys Phe Ala Lys Ala Val Gly
                 425                 430                 435

 Gln Gly Cys Val Glu Ile Gly Ser Gln Arg Tyr Lys Leu Gly Val
                 440                 445                 450

 Arg Leu Tyr Tyr Arg Val Met Glu Ser Met Leu Lys Ser Glu Glu
                 455                 460                 465

 Glu Arg Leu Ser Ile Gln Asn Phe Ser Lys Leu Leu Asn Asp Asn
                 470                 475                 480

 Ile Phe His Met Ser Leu Leu Ala Cys Ala Leu Glu Val Val Met
                 485                 490                 495

 Ala Thr Tyr Ser Arg Ser Thr Ser Gln Asn Leu Asp Ser Gly Thr
                 500                 505                 510

 Asp Leu Ser Phe Pro Trp Ile Leu Asn Val Leu Asn Leu Lys Ala
                 515                 520                 525

 Phe Asp Phe Tyr Lys Val Ile Glu Ser Phe Ile Lys Ala Glu Gly
                 530                 535                 540

 Asn Leu Thr Arg Glu Met Ile Lys His Leu Glu Arg Cys Glu His
                 545                 550                 555

 Arg Ile Met Glu Ser Leu Ala Trp Leu Ser Asp Ser Pro Leu Phe
                 560                 565                 570

 Asp Leu Ile Lys Gln Ser Lys Asp Arg Glu Gly Pro Thr Asp His
                 575                 580                 585

 Leu Glu Ser Ala Cys Pro Leu Asn Leu Pro Leu Gln Asn Asn His
                 590                 595                 600

 Thr Ala Ala Asp Met Tyr Leu Ser Pro Val Arg Ser Pro Lys Lys
                 605                 610                 615

 Lys Gly Ser Thr Thr Arg Val Asn Ser Thr Ala Asn Ala Glu Thr
                 620                 625                 630

 Gln Ala Thr Ser Ala Phe Gln Thr Gln Lys Pro Leu Lys Ser Thr
                 635                 640                 645

 Ser Leu Ser Leu Phe Tyr Lys Lys Val Tyr Arg Leu Ala Tyr Leu
                 650                 655                 660

 Arg Leu Asn Thr Leu Cys Glu Arg Leu Leu Ser Glu His Pro Glu
                 665                 670                 675

 Leu Glu His Ile Ile Trp Thr Leu Phe Gln His Thr Leu Gln Asn
                 680                 685                 690

 Glu Tyr Glu Leu Met Arg Asp Arg His Leu Asp Gln Ile Met Met
                 695                 700                 705

 Cys Ser Met Tyr Gly Ile Cys Lys Val Lys Asn Ile Asp Leu Lys
                 710                 715                 720

 Phe Lys Ile Ile Val Thr Ala Tyr Lys Asp Leu Pro His Ala Val
                 725                 730                 735

 Gln Glu Thr Phe Lys Arg Val Leu Ile Lys Glu Glu Glu Tyr Asp
                 740                 745                 750

 Ser Ile Ile Val Phe Tyr Asn Ser Val Phe Met Gln Arg Leu Lys
                 755                 760                 765

 Thr Asn Ile Leu Gln Tyr Ala Ser Thr Arg Pro Pro Thr Leu Ser
                 770                 775                 780

 Pro Ile Pro His Ile Pro Arg Ser Pro Tyr Lys Phe Pro Ser Ser
                 785                 790                 795

 Pro Leu Arg Ile Pro Gly Gly Asn Ile Tyr Ile Ser Pro Leu Lys
                 800                 805                 810

 Ser Pro Tyr Lys Ile Ser Glu Gly Leu Pro Thr Pro Thr Lys Met
                 815                 820                 825

 Thr Pro Arg Ser Arg Ile Leu Val Ser Ile Gly Glu Ser Phe Gly
                 830                 835                 840

 Thr Ser Glu Lys Phe Gln Lys Ile Asn Gln Met Val Cys Asn Ser
                 845                 850                 855

 Asp Arg Val Leu Lys Arg Ser Ala Glu Gly Ser Asn Pro Pro Lys
                 860                 865                 870

 Pro Leu Lys Lys Leu Arg Phe Asp Ile Glu Gly Ser Asp Glu Ala
                 875                 880                 885

 Asp Gly Ser Lys His Leu Pro Gly Glu Ser Lys Phe Gln Gln Lys
                 890                 895                 900

 Leu Ala Glu Met Thr Ser Thr Arg Thr Arg Met Gln Lys Gln Lys
                 905                 910                 915

 Met Asn Asp Ser Met Asp Thr Ser Asn Lys Glu Glu Lys
                 920                 925

<210> 5284
<211> 7947
<212> DNA
<213> Homo sapien

<400> 5284
 ggatccacgc ttagtgggaa actggaggga tcaatggaca gagagaagtc 50

 agattaatag gagtgaggaa aaacaatggc ttgaaaaaac agaaggttat 100

 agtctaagaa agcattctat aattataatt tcaaaggtag agcagttttg 150

 agagatagca agcccaatgc agccatggga ctggtttgct taagtgaagt 200

 gaaggtaatg ctcactgggt ttaatgagat gaagaaatgg aaggttaggg 250

 tgttgaatgg gtcttttacc tagatatttt gatcatctag gtcaaatgat 300

 cgcaggagtt gggatggaca gaaaggtgaa gtgccataat cttcagtgtg 350

 ggaatataat ctataggtta atggaagcca gtggcctgta ggacaacagc 400

 aggagtagag ggatctatct aaaaagtatt gaggtcagaa caagggattt 450

 cacatgagta ttggattaat ggttttggaa gttaaaatga cactgctgac 500

 accatcttcc atatggattt ttggggggaa aaaaaggaag actggaaggg 550

 aattgaatcc tcagggtttt aactctcatt gaaaatcctc ttgtaatgac 600

 cccagttgga agtagtaaac tcagacctcc ttgtgggctt tgagttacca 650

 ttagaagaag caaaggtccg tttccatttt atccacctga gcccactaaa 700

 caagatgcaa gattcctcca tggcccttag aacaaagttg atttccttga 750

 aaaccttggg aacccataat aaacaggacc ccagctgatt gtagatctcc 800

 tgggaagcta cttaaaactg gaaactgatt tgaataaaag gatcctggtc 850

 ttgcaaaagc tttactctgt tcataaatgt agtcgtaaaa tgaagacaaa 900

 attgataata tggggacata aaggataaaa gaggaaaaaa attttttcac 950

 tgcaatcttt cgaggcagat cacttttata taagtctcca tattgtaaat 1000

 gcagaaacct aggctctgag aggttatttt gctgatgtca tacagctagg 1050

 aagaacccca gtctgtgggt ctctacagcc cactcacttg tggtgattcc 1100

 caggggacca ggctcaggac gcaggtgggg agccctgggc ttactcagtg 1150

 cttgactggc cagaggggag aatccgggtg gcggccccac ccttgcctag 1200

 catttgggac cacccatgca agggaggagc cagtaccgtc actagttact 1250

 aggcagaggg gtagtggtgg tggaatatag agctcatgtg atccgtcaca 1300

 tgacagcaga tccgcggaag ggcagaatgg gactccaagc ctggtgagaa 1350

 attgagaggg ctcgggagaa agggatcacg ttggagggag cacacattgg 1400

 gagggtggga acacaaggac aacgtagctc ccactgaaac ccacctgctg 1450

 cccctacagc ctcctagggc tctttgccct catcctctct ggcaaatgca 1500

 gttacagccc ggagcccgac cagcggagga cgtgagttga cttagcacag 1550

 actgccccct tccccatacc ctgttctgcc tcccactgtc ctggtcctag 1600

 cttctctcac ccccgtgcca gctcctagta cgcactccat agcttcatct 1650

 ctatgttcct agcctcagtc cccttcattc acctcatgtg atctgtatct 1700

 gctcctagga tcctccccaa ggtctcagct cctaatctgg aaccttccat 1750

 gaccaatatt ttccatctcc accctaacca aagccatgtc cctgacccct 1800

 gaccctacag gctgccccca ggctgggtgt ccctgggccg tgcggaccct 1850

 gaggaagagc tgagtctcac ctttgccctg agacagcaga atgtggaaag 1900

 actctcggag ctggtgcagg ctgtgtcgga tcccagctct cctcaatacg 1950

 gtgccttttg ggactgagga caggatgtgg gatgcggtgg agggacacag 2000

 ggctgggttg ggcatggaat ggcgatcatg tcagagcctg ccaagacact 2050

 tgtgttcctc aggctagaaa cctaaaaggg gatgtggttc agtatacagg 2100

 ctttatgatc aaatacgaac tcaaattctg actctgctac ttactagcta 2150

 ccaggcatct agtacaactt acgttctttc ccctaccctc aaatccattc 2200

 taatttcctc ttttgttcac atactaaggc tgccagttct aactcccaaa 2250

 gagcctttgg attaatctcc ttcttgccgt cttttgttac gaccaactcc 2300

 gttatttatt cccactcctg gactactgcc cagctcccca gctgatctgc 2350

 agtctcctcc ctccacccca cccctcactg tactccccca ctctgcttca 2400

 aaacagtctc tccaacagtc aaaatggatt ggtctctctg tactcctaca 2450

 gcaggggagt gtgtgcttgt gaactgcaga ggctggggac ggggcagtgt 2500

 gacatagtgt gcatggcagg aaacagtgac tcaccattcg tgttaagctt 2550

 aaaatcaaaa agtatgcaaa tttgagtaaa ctgaataact ggtgccgaaa 2600

 gatttgaaaa catttaccgg acataagctt aaaattaaaa tggaaaattt 2650

 atatgtatta actcattcat tttcatgatc atggcaatac atgctgtggt 2700

 gcgacatttg caacttactg gcctttaggg taaatccata ttattggcca 2750

 tggcatttca agtctctcca gccttttctt ctctgcttcc caagtacacc 2800

 tacacctgca cacatagccc tcctttaccc tgttccaggc tttgggaagt 2850

 cctgatgtct catagttgag gtccaaaagg gggagtttgg gaaagcaatg 2900

 aatgagggca agtgcctctt ctgaatccct gcaggaaaat acctgaccct 2950

 agagaatgtg gctgatctgg tgaggccatc cccactgacc ctccacacgg 3000

 tgcaaaaatg gctcttggca gccggagccc agaagtgcca ttctgtgatc 3050

 acacaggact ttctgacttg ctggctgagc atccggtgag aggaaatgat 3100

 tgctccatgg agggcaccag tcatcccatc agtgagatgg atgggaggga 3150

 gttgagagct tgctggggct tgtgggtggg agctaatgca tggggagaca 3200

 gtgactgact gcccagggat gctcagaggt agcttcttct gttccgtttt 3250

 gagctttctg acctctgttc tctgacctcc agacaagcag agctgctgct 3300

 ccctggggct gagtttcatc actatgtggg aggacctacg gaaacccatg 3350

 ttgtaaggtc cccacatccc taccagcttc cacaggcctt ggccccccat 3400

 gtggactttg gtaacaccta tggggtgaat gggggatggg gcacacagat 3450

 ccaggggctg aggaagttta gatgccattg gggactgggg gtggggtggt 3500

 tgtaaggtgg gcattacagt ctataagatc tcctcaagcc tgacttctcc 3550

 ctacagtggg gggactgcac cgttttcccc caacatcatc cctgaggcaa 3600

 cgtcctgagc cgcaggtgac agggactgta ggcctgcatc tgggggtaac 3650

 cccctctgtg atccgtaagc gatacaactt gacctcacaa gacgtgggct 3700

 ctggcaccag caataacagc caagcctgtg cccaggtgag ccaagcaaag 3750

 agccccaggg tcctcatagc ctccccacag tgtcctcaat tccttaccac 3800

 cctgggactc accctcggac ccacgatctc tgctctgact ccctccatag 3850

 ttcctggagc agtatttcca tgactcagac ctggctcagt tcatgcgcct 3900

 cttcggtggc aactttgcac atcaggcatc agtagcccgt gtggttggac 3950

 aacagggccg gggccgggcc gggattgagg ccagtctaga tgtgcagtac 4000

 ctgatgagtg ctggtgccaa catctccacc tgggtctaca gtagccctgg 4050

 tactaccaag aggactggac agtggggaag ggggtgggag atgggtgttg 4100

 atccctgctc cctcaaggga atgctataag ctggagagag atcctgacaa 4150

 cccccagtga ctatctttgt gcccatccct caaaaaaaaa aaaaaaaaaa 4200

 tccaggccgg catgagggac aggagccctt cctgcagtgg ctcatgctgc 4250

 tcagtaatga gtcagccctg ccacatgtgc atactgtgag ctatggagat 4300

 gatgaggact ccctcagcag cgcctacatc cagcgggtca acactgagct 4350

 catgaaggct gccgctcggg gtctcaccct gctcttcgcc tcaggtgacc 4400

 tcctacccta aacttagaca acgcttacac ctctgcacgc ctgggtgctt 4450

 tgactccaca gtgatccctg agcctggtct ctgactcata atctgacact 4500

 cagaccttcc agtagggacc actgacctga cctctacact ctgacctcct 4550

 acagtaacaa atttcccctc tgacatccga acccacatac taagccctaa 4600

 ccaattaata tgaatgctac acttggtctc tctcaggtga cagtggggcc 4650

 gggtgttggt ctgtctctgg aagacaccag ttccgcccta ccttccctgc 4700

 ctccaggtaa gtactctagc ctaccactca ggtataacca ccacctttca 4750

 cttgtgatct catgatgtag aacctttgtc ttgaccccac catgtgctcc 4800

 tgtggttcag ccttaagctt tgcctgccct ggttgctgta ctcctgtctc 4850

 ttcttcctgc aggtcccagg ccccaaatct cttgtgtggg atacagggtc 4900

 atagctgttc cttttcgtca gttcccaggc atttgagtgg aagatttggt 4950

 gggtgttctg tacagaaaag tgtgcacagt cacctcaggc catgccttga 5000

 aggctcaaaa tctcttagtc aatcccatat acatgcttcc ccacagagtc 5050

 tagttcctcc agcaagacct gggctatact cacccctccc cacatatctt 5100

 ggaggtcccc ttgggtcccc tactatccaa atgctgtctt ctcccctcag 5150

 cccctatgtc accacagtgg gaggcacatc cttccaggaa cctttcctca 5200

 tcacaaatga aattgttgac tatatcagtg gtggtggctt cagcaatgtg 5250

 ttcccacggc cttcatacca ggtacgtgtg tttgtgtgga tggatgcagg 5300

 gtaagagtga ggatggggga tcctcagttc agctgactgc tgggcaggcc 5350

 acatgccaat actcactcaa aaatgccttt caggaggaag ctgtaacgaa 5400

 gttcctgagc tctagccccc acctgccacc atccagttac ttcaatgcca 5450

 gtggccgtgc ctacccagat gtggctgcac tttctgatgg ctactgggtg 5500

 gtcagcaaca gagtgcccat tccatgggtg tccggaacct cggtgagaat 5550

 cagcccatct ccaaactctc actcaggaac tacccttacc ccctaacacc 5600

 ttgaacacct tgcacctaga acccctgact ccttagagat gtctgatact 5650

 ttaaagcatc actcccaaaa agtccaatca ctcagaaccc ctgaccttac 5700

 ttgcaccttc actcttgtag gcctctactc cagtgtttgg ggggatccta 5750

 tccttgatca atgagcacag gatccttagt ggccgccccc ctcttggctt 5800

 tctcaaccca aggctctacc agcagcatgg ggcaggactc tttgatgtaa 5850

 gtatggaagg gaagggtgtg gacgttttca aacaactatg gggagtgcta 5900

 agggggactt gggggcagtt agggtggtgt ggaatagcct ttgaaatgtg 5950

 agtacagggt gaggagatat actctttaag tactggtact agtaggccca 6000

 gatctgatgc cagcctcctc cctaggtaac ccgtggctgc catgagtcct 6050

 gtctggatga agaggtagag ggccagggtt tctgctctgg tcctggctgg 6100

 gatcctgtaa caggctgggg aacacccaac ttcccagctt tgctgaagac 6150

 tctactcaac ccctgaccct ttcctatcag gagagatggc ttgtcccctg 6200

 ccctgaagct ggcagttcag tcccttattc tgccctgttg gaagccctgc 6250

 tgaaccctca actattgact gctgcagaca gcttatctcc ctaaccctga 6300

 aatgcggtga gcttgacttg actcccaacc ctaccatgct ccatcatact 6350

 caggtctccc tactcctgcc ttagattcct caataagatg ctgtaactag 6400

 cattttttga atgcctctcc ctccgcatct catctttctc ttttcaatca 6450

 ggcttttcca aagggttgta tacagactct gtgcactatt tcacttgata 6500

 ttcattcccc aattcactgc aaggagacct ctactgtcac cgtttactct 6550

 ttcctaccct gacatccaga aacaatggcc tccagtgcat acttctcaat 6600

 ctttgcttta tggcctttcc atcatagttg cccactccct ctccttactt 6650

 agcttccagg tcttaacttc tctgactact cttgtcttcc tctctcatca 6700

 atttctgctt cttcatggaa tgctgacctt cattgctcca tttgtagatt 6750

 tttgctcttc tcagtttact cattgtcccc tggaacaaat cactgacatc 6800

 tacaaccatt accatctcac taaataagac tttctatcca ataatgattg 6850

 atacctcaaa tgtaagatgc gtgatactca acatttcatc gtccaccttc 6900

 ccaaccccaa acaattccat ctcgtttctt cttggtaaat gatgctatgc 6950

 tttttccaac caagccagaa acctgtgtca tcttttcacc ccaccttcaa 7000

 tcaacaagtc ctcaatcaac aagtcctact gactgcacat cttaaatata 7050

 tctttatcag tccacaagtc cttccaatta tatttcccaa gtatatctag 7100

 aacttatcca cttatatccc cactgctact accttagttt agggctatat 7150

 tctcttgaaa aaaagtgtcc ttacttcctg ccaatcccca agtcatcttc 7200

 cagagtaaaa tgcaaatccc atcaggccac ttggatgaaa acccttcaag 7250

 gattactgga tagaattcag gctttcccct ccagccccca atcatagctc 7300

 acaaaccttc cttgctattt gttcttaagt aaaaaatcat ttttcctcct 7350

 ccctccccaa accccaagga actctcactc ttgctcaagc tgttccgtcc 7400

 ccttaccacc cctgatacaa ctgccaggtt aatttccaga attcttgcaa 7450

 gactcagttc agaagtcacc ttctttcgtg aatgttttga ttccctgagg 7500

 ctactttatt ttggtatggc tgaaaaatcc tagattttct aaacaaaacc 7550

 tgtttgaatc ttggttctga tatggactag gagagagact gggtcaagta 7600

 agcttatctc cctgaggctg tttcctcgtc tgttaagtgt gaatatcaat 7650

 acctgccttt cataatcacc agggaataaa gtggaataat gttgataaca 7700

 gtgcttggca cctggaagta ggtggcagat gttaacgccc ttcctccctt 7750

 gcactgcgcc ccctgtgcct acctctagca ttgtaacgac cacatagtat 7800

 tgaaatggcc agtttacttg tctgccttcc tttccaagac cgttggtgcc 7850

 tagaggacta gaatcgtgtc ctatttaact ttgtgttccc aggtcctagc 7900

 tcaggagttg gcaaataaga attaaatgtc tgctacaccg aaacaaa 7947

<210> 5285
<211> 2984
<212> DNA
<213> Homo sapien

<400> 5285
 taactgagcg aggagcaatt gattaatagc tcggcgaggg gactcactga 50

 ctgttataat aacactacac cagcaactcc tggcttccca gcagccggaa 100

 cacagacagg agagagtcag tggcaaatag acatttttct tatttcttaa 150

 aaaacagcaa cttgtttgct acttttattt ctgttgattt ttttttcttg 200

 gtgtgtgtgg tggttgtttt taagtgtgga gggcaaaagg agataccatc 250

 ccaggctcag tccaacccct ctccaaaacg gcttttctga cactccaggt 300

 agcgagggag ttgggtctcc aggttgtgcg aggagcaaat gatgaccgcc 350

 aaggccgtag acaaaatccc agtaactctc agtggttttg tgcaccagct 400

 gtctgacaac atctacccgg tggaggacct cgccgccacg tcggtgacca 450

 tctttcccaa tgccgaactg ggaggcccct ttgaccagat gaacggagtg 500

 gccggagatg gcatgatcaa cattgacatg actggagaga agaggtcgtt 550

 ggatctccca tatcccagca gctttgctcc cgtctctgca cctagaaacc 600

 agaccttcac ttacatgggc aagttctcca ttgaccctca gtaccctggt 650

 gccagctgct acccagaagg cataatcaat attgtgagtg caggcatctt 700

 gcaaggggtc acttccccag cttcaaccac agcctcatcc agcgtcacct 750

 ctgcctcccc caacccactg gccacaggac ccctgggtgt gtgcaccatg 800

 tcccagaccc agcctgacct ggaccacctg tactctccgc caccgcctcc 850

 tcctccttat tctggctgtg caggagacct ctaccaggac ccttctgcgt 900

 tcctgtcagc agccaccacc tccacctctt cctctctggc ctacccacca 950

 cctccttcct atccatcccc caagccagcc acggacccag gtctcttccc 1000

 aatgatccca gactatcctg gattctttcc atctcagtgc cagagagacc 1050

 tacatggtac agctggccca gaccgtaagc cctttccctg cccactggac 1100

 accctgcggg tgccccctcc actcactcca ctctctacaa tccgtaactt 1150

 taccctgggg ggccccagtg ctggggtgac cggaccaggg gccagtggag 1200

 gcagcgaggg accccggctg cctggtagca gctcagcagc agcagcagcc 1250

 gccgccgccg ccgcctataa cccacaccac ctgccactgc ggcccattct 1300

 gaggcctcgc aagtacccca acagacccag caagacgccg gtgcacgaga 1350

 ggccctaccc gtgcccagca gaaggctgcg accggcggtt ctcccgctct 1400

 gacgagctga cacggcacat ccgaatccac actgggcata agcccttcca 1450

 gtgtcggatc tgcatgcgca acttcagccg cagtgaccac ctcaccaccc 1500

 atatccgcac ccacaccggt gagaagccct tcgcctgtga ctactgtggc 1550

 cgaaagtttg cccggagtga tgagaggaag cgccacacca agatccacct 1600

 gagacagaaa gagcggaaaa gcagtgcccc ctctgcatcg gtgccagccc 1650

 cctctacagc ctcctgctct gggggcgtgc agcctggggg taccctgtgc 1700

 agcagtaaca gcagcagtct tggcggaggg ccgctcgccc cttgctcctc 1750

 tcggacccgg acaccttgag atgagactca ggctgataca ccagctccca 1800

 aaggtcccgg aggccctttg tccactggag ctgcacaaca aacactacca 1850

 ccctttcctg tccctctctc cctttgttgg gcaaagggct ttggtggagc 1900

 tagcactgcc ccctttccac ctagaagcag gttcttccta aaacttagcc 1950

 cattctagtc tctcttaggt gagttgacta tcaacccaag gcaaagggga 2000

 ggctcagaag gaggtggtgt ggggatcccc tggccaagag ggctgaggtc 2050

 tgaccctgct ttaaagggtt gtttgactag gttttgctac cccacttccc 2100

 cttattttga cccatcacag gtttttgacc ctggatgtca gagttgatct 2150

 aagacgtttt ctacaatagg ttgggagatg ctgatccctt caagtgggga 2200

 cagcaaaaag acaagcaaaa ctgatgtgca ctttatggct tgggactgat 2250

 ttgggggaca ttgtacagtg agtgaagtat agcctttatg ccacactctg 2300

 tggccctaaa atggtgaatc agagcatatc tagttgtctc aacccttgaa 2350

 gcaatatgta ttatatactc agagaacaga agtgcaatgt gatgggagga 2400

 acgtagcaat atctgctcct tttcgagttg tttgagaaat gtaggctatt 2450

 ttttcagtgt atatccactc agattttgtg tatttttgat gtacccacac 2500

 tgttctctaa attctgaatc tttgggaaaa aatgtaaagc atttatgatc 2550

 tcagaggtta acttatttaa gggggatgta catattctct gaaactagga 2600

 tgcatgcaat tgtgttggaa gtgtccttgg tcgccttgtg tgatgtagac 2650

 aaatgttaca aggctgcatg taaatgggtt gccttattat ggagaaaaaa 2700

 atcactccct gagtttagta tggctgtata tttatgccta ttaatatttg 2750

 gaattttttt tagaaagtat atttttgtat gctttgtttt gtgacttaaa 2800

 agtgttacct ttgtagtcaa atttcagata agaatgtaca taatgttacc 2850

 ggagctgatt tgtttggtca ttagctctta atagttgtga aaaaataaat 2900

 ctattctaac gcaaaaccac taactgaagt tcagatataa tggatggttt 2950

 gtgactatag tgtaaataaa tacttttcaa caat 2984

<210> 5286
<211> 476
<212> PRT
<213> Homo sapien

<400> 5286
 Met Met Thr Ala Lys Ala Val Asp Lys Ile Pro Val Thr Leu Ser
   1               5                  10                  15

 Gly Phe Val His Gln Leu Ser Asp Asn Ile Tyr Pro Val Glu Asp
                  20                  25                  30

 Leu Ala Ala Thr Ser Val Thr Ile Phe Pro Asn Ala Glu Leu Gly
                  35                  40                  45

 Gly Pro Phe Asp Gln Met Asn Gly Val Ala Gly Asp Gly Met Ile
                  50                  55                  60

 Asn Ile Asp Met Thr Gly Glu Lys Arg Ser Leu Asp Leu Pro Tyr
                  65                  70                  75

 Pro Ser Ser Phe Ala Pro Val Ser Ala Pro Arg Asn Gln Thr Phe
                  80                  85                  90

 Thr Tyr Met Gly Lys Phe Ser Ile Asp Pro Gln Tyr Pro Gly Ala
                  95                 100                 105

 Ser Cys Tyr Pro Glu Gly Ile Ile Asn Ile Val Ser Ala Gly Ile
                 110                 115                 120

 Leu Gln Gly Val Thr Ser Pro Ala Ser Thr Thr Ala Ser Ser Ser
                 125                 130                 135

 Val Thr Ser Ala Ser Pro Asn Pro Leu Ala Thr Gly Pro Leu Gly
                 140                 145                 150

 Val Cys Thr Met Ser Gln Thr Gln Pro Asp Leu Asp His Leu Tyr
                 155                 160                 165

 Ser Pro Pro Pro Pro Pro Pro Pro Tyr Ser Gly Cys Ala Gly Asp
                 170                 175                 180

 Leu Tyr Gln Asp Pro Ser Ala Phe Leu Ser Ala Ala Thr Thr Ser
                 185                 190                 195

 Thr Ser Ser Ser Leu Ala Tyr Pro Pro Pro Pro Ser Tyr Pro Ser
                 200                 205                 210

 Pro Lys Pro Ala Thr Asp Pro Gly Leu Phe Pro Met Ile Pro Asp
                 215                 220                 225

 Tyr Pro Gly Phe Phe Pro Ser Gln Cys Gln Arg Asp Leu His Gly
                 230                 235                 240

 Thr Ala Gly Pro Asp Arg Lys Pro Phe Pro Cys Pro Leu Asp Thr
                 245                 250                 255

 Leu Arg Val Pro Pro Pro Leu Thr Pro Leu Ser Thr Ile Arg Asn
                 260                 265                 270

 Phe Thr Leu Gly Gly Pro Ser Ala Gly Val Thr Gly Pro Gly Ala
                 275                 280                 285

 Ser Gly Gly Ser Glu Gly Pro Arg Leu Pro Gly Ser Ser Ser Ala
                 290                 295                 300

 Ala Ala Ala Ala Ala Ala Ala Ala Ala Tyr Asn Pro His His Leu
                 305                 310                 315

 Pro Leu Arg Pro Ile Leu Arg Pro Arg Lys Tyr Pro Asn Arg Pro
                 320                 325                 330

 Ser Lys Thr Pro Val His Glu Arg Pro Tyr Pro Cys Pro Ala Glu
                 335                 340                 345

 Gly Cys Asp Arg Arg Phe Ser Arg Ser Asp Glu Leu Thr Arg His
                 350                 355                 360

 Ile Arg Ile His Thr Gly His Lys Pro Phe Gln Cys Arg Ile Cys
                 365                 370                 375

 Met Arg Asn Phe Ser Arg Ser Asp His Leu Thr Thr His Ile Arg
                 380                 385                 390

 Thr His Thr Gly Glu Lys Pro Phe Ala Cys Asp Tyr Cys Gly Arg
                 395                 400                 405

 Lys Phe Ala Arg Ser Asp Glu Arg Lys Arg His Thr Lys Ile His
                 410                 415                 420

 Leu Arg Gln Lys Glu Arg Lys Ser Ser Ala Pro Ser Ala Ser Val
                 425                 430                 435

 Pro Ala Pro Ser Thr Ala Ser Cys Ser Gly Gly Val Gln Pro Gly
                 440                 445                 450

 Gly Thr Leu Cys Ser Ser Asn Ser Ser Ser Leu Gly Gly Gly Pro
                 455                 460                 465

 Leu Ala Pro Cys Ser Ser Arg Thr Arg Thr Pro
                 470                 475

<210> 5287
<211> 3597
<212> DNA
<213> Homo sapien

<400> 5287
 ggcgaatgga gcaggggcgc gcagataatt aaagatttac acacagctgg 50

 aagaaatcat agagaagccg ggcgtggtgg ctcatgccta taatcccagc 100

 acttttggag gctgaggcgg gcagatcact tgagatcagg agttcgagac 150

 cagcctggtg ccttggcatc tcccaatggg gtggctttgc tctgggctcc 200

 tgttccctgt gagctgcctg gtcctgctgc aggtggcaag ctctgggaac 250

 atgaaggtct tgcaggagcc cacctgcgtc tccgactaca tgagcatctc 300

 tacttgcgag tggaagatga atggtcccac caattgcagc accgagctcc 350

 gcctgttgta ccagctggtt tttctgctct ccgaagccca cacgtgtatc 400

 cctgagaaca acggaggcgc ggggtgcgtg tgccacctgc tcatggatga 450

 cgtggtcagt gcggataact atacactgga cctgtgggct gggcagcagc 500

 tgctgtggaa gggctccttc aagcccagcg agcatgtgaa acccagggcc 550

 ccaggaaacc tgacagttca caccaatgtc tccgacactc tgctgctgac 600

 ctggagcaac ccgtatcccc ctgacaatta cctgtataat catctcacct 650

 atgcagtcaa catttggagt gaaaacgacc cggcagattt cagaatctat 700

 aacgtgacct acctagaacc ctccctccgc atcgcagcca gcaccctgaa 750

 gtctgggatt tcctacaggg cacgggtgag ggcctgggct cagtgctata 800

 acaccacctg gagtgagtgg agccccagca ccaagtggca caactcctac 850

 agggagccct tcgagcagca cctcctgctg ggcgtcagcg tttcctgcat 900

 tgtcatcctg gccgtctgcc tgttgtgcta tgtcagcatc accaagatta 950

 agaaagaatg gtgggatcag attcccaacc cagcccgcag ccgcctcgtg 1000

 gctataataa tccaggatgc tcaggggtca cagtgggaga agcggtcccg 1050

 aggccaggaa ccagccaagt gcccacactg gaagaattgt cttaccaagc 1100

 tcttgccctg ttttctggag cacaacatga aaagggatga agatcctcac 1150

 aaggctgcca aagagatgcc tttccagggc tctggaaaat cagcatggtg 1200

 cccagtggag atcagcaaga cagtcctctg gccagagagc atcagcgtgg 1250

 tgcgatgtgt ggagttgttt gaggccccgg tggagtgtga ggaggaggag 1300

 gaggtagagg aagaaaaagg gagcttctgt gcatcgcctg agagcagcag 1350

 ggatgacttc caggagggaa gggagggcat tgtggcccgg ctaacagaga 1400

 gcctgttcct ggacctgctc ggagaggaga atgggggctt ttgccagcag 1450

 gacatggggg agtcatgcct tcttccacct tcgggaagta cgagtgctca 1500

 catgccctgg gatgagttcc caagtgcagg gcccaaggag gcacctccct 1550

 ggggcaagga gcagcctctc cacctggagc caagtcctcc tgccagcccg 1600

 acccagagtc cagacaacct gacttgcaca gagacgcccc tcgtcatcgc 1650

 aggcaaccct gcttaccgca gcttcagcaa ctccctgagc cagtcaccgt 1700

 gtcccagaga gctgggtcca gacccactgc tggccagaca cctggaggaa 1750

 gtagaacccg agatgccctg tgtcccccag ctctctgagc caaccactgt 1800

 gccccaacct gagccagaaa cctgggagca gatcctccgc cgaaatgtcc 1850

 tccagcatgg ggcagctgca gcccccgtct cggcccccac cagtggctat 1900

 caggagtttg tacatgcggt ggagcagggt ggcacccagg ccagtgcggt 1950

 ggtgggcttg ggtcccccag gagaggctgg ttacaaggcc ttctcaagcc 2000

 tgcttgccag cagtgctgtg tccccagaga aatgtgggtt tggggctagc 2050

 agtggggaag aggggtataa gcctttccaa gacctcattc ctggctgccc 2100

 tggggaccct gccccagtcc ctgtcccctt gttcaccttt ggactggaca 2150

 gggagccacc tcgcagtccg cagagctcac atctcccaag cagctcccca 2200

 gagcacctgg gtctggagcc gggggaaaag gtagaggaca tgccaaagcc 2250

 cccacttccc caggagcagg ccacagaccc ccttgtggac agcctgggca 2300

 gtggcattgt ctactcagcc cttacctgcc acctgtgcgg ccacctgaaa 2350

 cagtgtcatg gccaggagga tggtggccag acccctgtca tggccagtcc 2400

 ttgctgtggc tgctgctgtg gagacaggtc ctcgccccct acaacccccc 2450

 tgagggcccc agacccctct ccaggtgggg ttccactgga ggccagtctg 2500

 tgtccggcct ccctggcacc ctcgggcatc tcagagaaga gtaaatcctc 2550

 atcatccttc catcctgccc ctggcaatgc tcagagctca agccagaccc 2600

 ccaaaatcgt gaactttgtc tccgtgggac ccacatacat gagggtctct 2650

 taggtgcatg tcctcttgtt gctgagtctg cagatgagga ctagggctta 2700

 tccatgcctg ggaaatgcca cctcctggaa ggcagccagg ctggcagatt 2750

 tccaaaagac ttgaagaacc atggtatgaa ggtgattggc cccactgacg 2800

 ttggcctaac actgggctgc agagactgga ccccgcccag cattgggctg 2850

 ggctcgccac atcccatgag agtagagggc actgggtcgc cgtgccccac 2900

 ggcaggcccc tgcaggaaaa ctgaggccct tgggcacctc gacttgtgaa 2950

 cgagttgttg gctgctccct ccacagcttc tgcagcagac tgtccctgtt 3000

 gtaactgccc aaggcatgtt ttgcccacca gatcatggcc cacgtggagg 3050

 cccacctgcc tctgtctcac tgaactagaa gccgagccta gaaactaaca 3100

 cagccatcaa gggaatgact tgggcggcct tgggaaatcg atgagaaatt 3150

 gaacttcagg gagggtggtc attgcctaga ggtgctcatt catttaacag 3200

 agcttcctta ggttgatgct ggaggcagaa tcccggctgt caaggggtgt 3250

 tcagttaagg ggagcaacag aggacatgaa aaattgctat gactaaagca 3300

 gggacaattt gctgccaaac acccatgccc agctgtatgg ctgggggctc 3350

 ctcgtatgca tggaaccccc agaataaata tgctcagcca ccctgtgggc 3400

 cgggcaatcc agacagcagg cataaggcac cagttaccct gcatgttggc 3450

 ccagacctca ggtgctaggg aaggcgggaa ccttgggttg agtaatgctc 3500

 gtctgtgtgt tttagtttca tcacctgtta tctgtgtttg ctgaggagag 3550

 tggaacagaa ggggtggagt tttgtataaa taaagtttct ttgtctc 3597

<210> 5288
<211> 825
<212> PRT
<213> Homo sapien

<400> 5288
 Met Gly Trp Leu Cys Ser Gly Leu Leu Phe Pro Val Ser Cys Leu
   1               5                  10                  15

 Val Leu Leu Gln Val Ala Ser Ser Gly Asn Met Lys Val Leu Gln
                  20                  25                  30

 Glu Pro Thr Cys Val Ser Asp Tyr Met Ser Ile Ser Thr Cys Glu
                  35                  40                  45

 Trp Lys Met Asn Gly Pro Thr Asn Cys Ser Thr Glu Leu Arg Leu
                  50                  55                  60

 Leu Tyr Gln Leu Val Phe Leu Leu Ser Glu Ala His Thr Cys Ile
                  65                  70                  75

 Pro Glu Asn Asn Gly Gly Ala Gly Cys Val Cys His Leu Leu Met
                  80                  85                  90

 Asp Asp Val Val Ser Ala Asp Asn Tyr Thr Leu Asp Leu Trp Ala
                  95                 100                 105

 Gly Gln Gln Leu Leu Trp Lys Gly Ser Phe Lys Pro Ser Glu His
                 110                 115                 120

 Val Lys Pro Arg Ala Pro Gly Asn Leu Thr Val His Thr Asn Val
                 125                 130                 135

 Ser Asp Thr Leu Leu Leu Thr Trp Ser Asn Pro Tyr Pro Pro Asp
                 140                 145                 150

 Asn Tyr Leu Tyr Asn His Leu Thr Tyr Ala Val Asn Ile Trp Ser
                 155                 160                 165

 Glu Asn Asp Pro Ala Asp Phe Arg Ile Tyr Asn Val Thr Tyr Leu
                 170                 175                 180

 Glu Pro Ser Leu Arg Ile Ala Ala Ser Thr Leu Lys Ser Gly Ile
                 185                 190                 195

 Ser Tyr Arg Ala Arg Val Arg Ala Trp Ala Gln Cys Tyr Asn Thr
                 200                 205                 210

 Thr Trp Ser Glu Trp Ser Pro Ser Thr Lys Trp His Asn Ser Tyr
                 215                 220                 225

 Arg Glu Pro Phe Glu Gln His Leu Leu Leu Gly Val Ser Val Ser
                 230                 235                 240

 Cys Ile Val Ile Leu Ala Val Cys Leu Leu Cys Tyr Val Ser Ile
                 245                 250                 255

 Thr Lys Ile Lys Lys Glu Trp Trp Asp Gln Ile Pro Asn Pro Ala
                 260                 265                 270

 Arg Ser Arg Leu Val Ala Ile Ile Ile Gln Asp Ala Gln Gly Ser
                 275                 280                 285

 Gln Trp Glu Lys Arg Ser Arg Gly Gln Glu Pro Ala Lys Cys Pro
                 290                 295                 300

 His Trp Lys Asn Cys Leu Thr Lys Leu Leu Pro Cys Phe Leu Glu
                 305                 310                 315

 His Asn Met Lys Arg Asp Glu Asp Pro His Lys Ala Ala Lys Glu
                 320                 325                 330

 Met Pro Phe Gln Gly Ser Gly Lys Ser Ala Trp Cys Pro Val Glu
                 335                 340                 345

 Ile Ser Lys Thr Val Leu Trp Pro Glu Ser Ile Ser Val Val Arg
                 350                 355                 360

 Cys Val Glu Leu Phe Glu Ala Pro Val Glu Cys Glu Glu Glu Glu
                 365                 370                 375

 Glu Val Glu Glu Glu Lys Gly Ser Phe Cys Ala Ser Pro Glu Ser
                 380                 385                 390

 Ser Arg Asp Asp Phe Gln Glu Gly Arg Glu Gly Ile Val Ala Arg
                 395                 400                 405

 Leu Thr Glu Ser Leu Phe Leu Asp Leu Leu Gly Glu Glu Asn Gly
                 410                 415                 420

 Gly Phe Cys Gln Gln Asp Met Gly Glu Ser Cys Leu Leu Pro Pro
                 425                 430                 435

 Ser Gly Ser Thr Ser Ala His Met Pro Trp Asp Glu Phe Pro Ser
                 440                 445                 450

 Ala Gly Pro Lys Glu Ala Pro Pro Trp Gly Lys Glu Gln Pro Leu
                 455                 460                 465

 His Leu Glu Pro Ser Pro Pro Ala Ser Pro Thr Gln Ser Pro Asp
                 470                 475                 480

 Asn Leu Thr Cys Thr Glu Thr Pro Leu Val Ile Ala Gly Asn Pro
                 485                 490                 495

 Ala Tyr Arg Ser Phe Ser Asn Ser Leu Ser Gln Ser Pro Cys Pro
                 500                 505                 510

 Arg Glu Leu Gly Pro Asp Pro Leu Leu Ala Arg His Leu Glu Glu
                 515                 520                 525

 Val Glu Pro Glu Met Pro Cys Val Pro Gln Leu Ser Glu Pro Thr
                 530                 535                 540

 Thr Val Pro Gln Pro Glu Pro Glu Thr Trp Glu Gln Ile Leu Arg
                 545                 550                 555

 Arg Asn Val Leu Gln His Gly Ala Ala Ala Ala Pro Val Ser Ala
                 560                 565                 570

 Pro Thr Ser Gly Tyr Gln Glu Phe Val His Ala Val Glu Gln Gly
                 575                 580                 585

 Gly Thr Gln Ala Ser Ala Val Val Gly Leu Gly Pro Pro Gly Glu
                 590                 595                 600

 Ala Gly Tyr Lys Ala Phe Ser Ser Leu Leu Ala Ser Ser Ala Val
                 605                 610                 615

 Ser Pro Glu Lys Cys Gly Phe Gly Ala Ser Ser Gly Glu Glu Gly
                 620                 625                 630

 Tyr Lys Pro Phe Gln Asp Leu Ile Pro Gly Cys Pro Gly Asp Pro
                 635                 640                 645

 Ala Pro Val Pro Val Pro Leu Phe Thr Phe Gly Leu Asp Arg Glu
                 650                 655                 660

 Pro Pro Arg Ser Pro Gln Ser Ser His Leu Pro Ser Ser Ser Pro
                 665                 670                 675

 Glu His Leu Gly Leu Glu Pro Gly Glu Lys Val Glu Asp Met Pro
                 680                 685                 690

 Lys Pro Pro Leu Pro Gln Glu Gln Ala Thr Asp Pro Leu Val Asp
                 695                 700                 705

 Ser Leu Gly Ser Gly Ile Val Tyr Ser Ala Leu Thr Cys His Leu
                 710                 715                 720

 Cys Gly His Leu Lys Gln Cys His Gly Gln Glu Asp Gly Gly Gln
                 725                 730                 735

 Thr Pro Val Met Ala Ser Pro Cys Cys Gly Cys Cys Cys Gly Asp
                 740                 745                 750

 Arg Ser Ser Pro Pro Thr Thr Pro Leu Arg Ala Pro Asp Pro Ser
                 755                 760                 765

 Pro Gly Gly Val Pro Leu Glu Ala Ser Leu Cys Pro Ala Ser Leu
                 770                 775                 780

 Ala Pro Ser Gly Ile Ser Glu Lys Ser Lys Ser Ser Ser Ser Phe
                 785                 790                 795

 His Pro Ala Pro Gly Asn Ala Gln Ser Ser Ser Gln Thr Pro Lys
                 800                 805                 810

 Ile Val Asn Phe Val Ser Val Gly Pro Thr Tyr Met Arg Val Ser
                 815                 820                 825

<210> 5289
<211> 2557
<212> DNA
<213> Homo sapien

<400> 5289
 gaattccggg agaagtgacc agagcaattt ctgcttttca cagggcgggt 50

 ttctcaacgg tgacttgtgg gcagtgcctt ctgctgagcg agtcatggcc 100

 cgaaggcaga actaactgtg cctgcagtct tcactctcag gatgcagccg 150

 aggtgggccc aaggggccac gatgtggctt ggagtcctgc tgacccttct 200

 gctctgttca agccttgagg gtcaagaaaa ctctttcaca atcaacagtg 250

 ttgacatgaa gagcctgccg gactggacgg tgcaaaatgg gaagaacctg 300

 accctgcagt gcttcgcgga tgtcagcacc acctctcacg tcaagcctca 350

 gcaccagatg ctgttctata aggatgacgt gctgttttac aacatctcct 400

 ccatgaagag cacagagagt tattttattc ctgaagtccg gatctatgac 450

 tcagggacat ataaatgtac tgtgattgtg aacaacaaag agaaaaccac 500

 tgcagagtac cagctgttgg tggaaggagt gcccagtccc agggtgacac 550

 tggacaagaa agaggccatc caaggtggga tcgtgagggt caactgttct 600

 gtcccagagg aaaaggcccc aatacacttc acaattgaaa aacttgaact 650

 aaatgaaaaa atggtcaagc tgaaaagaga gaagaattct cgagaccaga 700

 attttgtgat actggaattc cccgttgagg aacaggaccg cgttttatcc 750

 ttccgatgtc aagctaggat catttctggg atccatatgc agacctcaga 800

 atctaccaag agtgaactgg tcaccgtgac ggaatccttc tctacaccca 850

 agttccacat cagccccacc ggaatgatca tggaaggagc tcagctccac 900

 attaagtgca ccattcaagt gactcacctg gcccaggagt ttccagaaat 950

 cataattcag aaggacaagg cgattgtggc ccacaacaga catggcaaca 1000

 aggctgtgta ctcagtcatg gccatggtgg agcacagtgg caactacacg 1050

 tgcaaagtgg agtccagccg catatccaag gtcagcagca tcgtggtcaa 1100

 cataacagaa ctattttcca agcccgaact ggaatcttcc ttcacacatc 1150

 tggaccaagg tgaaagactg aacctgtcct gctccatccc aggagcacct 1200

 ccagccaact tcaccatcca gaaggaagat acgattgtgt cacagactca 1250

 agatttcacc aagatagcct caaagtcgga cagtgggacg tatatctgca 1300

 ctgcaggtat tgacaaagtg gtcaagaaaa gcaacacagt ccagatagtc 1350

 gtatgtgaaa tgctctccca gcccaggatt tcttatgatg cccagtttga 1400

 ggtcataaaa ggacagacca tcgaagtccg ttgcgaatcg atcagtggaa 1450

 ctttgcctat ttcttaccaa cttttaaaaa caagtaaagt tttggagaat 1500

 agtaccaaga actcaaatga tcctgcggta ttcaaagaca accccactga 1550

 agacgtcgaa taccagtgtg ttgcagataa ttgccattcc catgccaaaa 1600

 tgttaagtga ggttctgagg gtgaaggtga tagccccggt ggatgaggtc 1650

 cagatttcta tcctgtcaag taaggtggtg gagtctggag aggacattgt 1700

 gctgcaatgt gctgtgaatg aaggatctgg tcccatcacc tataagtttt 1750

 acagagaaaa agagggcaaa cccttctatc aaatgacctc aaatgccacc 1800

 caggcatttt ggaccaagca gaaggctagc aaggaacagg agggagagta 1850

 ttactgcaca gccttcaaca gagccaacca cgcctccagt gtccccagaa 1900

 gcaaaatact gacagtcaga gtcattcttg ccccatggaa gaaaggactt 1950

 attgcagtgg ttatcatcgg agtgatcatt gctctcttga tcattgcggc 2000

 caaatgttat tttctgagga aagccaaggc caagcagatg ccagtggaaa 2050

 tgtccaggcc agcagtacca cttctgaact ccaacaacga gaaaatgtca 2100

 gatcccaata tggaagctaa cagtcattac ggtcacaatg acgatgtcag 2150

 aaaccatgca atgaaaccaa taaatgataa taaagagcct ctgaactcag 2200

 acgtgcagta cacggaagtt caagtgtcct cagctgagtc tcacaaagat 2250

 ctaggaaaga aggacacaga gacagtgtac agtgaagtcc ggaaagctgt 2300

 ccctgatgcc gtggaaagca gatactctag aacggaaggc tcccttgatg 2350

 gaacttagac agcaaggcca gatgcacatc cctggaagga catccatgtt 2400

 ccgagaagaa cagataatcc ctgtatttca agacctctgt gcacttattt 2450

 atgaacctgc cctgctccca cagaacacag caattcctca ggctaagctg 2500

 ccggttctta aatccatcct gctaagttaa tgttgggtag aaagagatac 2550

 agagggg 2557

<210> 5290
<211> 738
<212> PRT
<213> Homo sapien

<400> 5290
 Met Gln Pro Arg Trp Ala Gln Gly Ala Thr Met Trp Leu Gly Val
   1               5                  10                  15

 Leu Leu Thr Leu Leu Leu Cys Ser Ser Leu Glu Gly Gln Glu Asn
                  20                  25                  30

 Ser Phe Thr Ile Asn Ser Val Asp Met Lys Ser Leu Pro Asp Trp
                  35                  40                  45

 Thr Val Gln Asn Gly Lys Asn Leu Thr Leu Gln Cys Phe Ala Asp
                  50                  55                  60

 Val Ser Thr Thr Ser His Val Lys Pro Gln His Gln Met Leu Phe
                  65                  70                  75

 Tyr Lys Asp Asp Val Leu Phe Tyr Asn Ile Ser Ser Met Lys Ser
                  80                  85                  90

 Thr Glu Ser Tyr Phe Ile Pro Glu Val Arg Ile Tyr Asp Ser Gly
                  95                 100                 105

 Thr Tyr Lys Cys Thr Val Ile Val Asn Asn Lys Glu Lys Thr Thr
                 110                 115                 120

 Ala Glu Tyr Gln Leu Leu Val Glu Gly Val Pro Ser Pro Arg Val
                 125                 130                 135

 Thr Leu Asp Lys Lys Glu Ala Ile Gln Gly Gly Ile Val Arg Val
                 140                 145                 150

 Asn Cys Ser Val Pro Glu Glu Lys Ala Pro Ile His Phe Thr Ile
                 155                 160                 165

 Glu Lys Leu Glu Leu Asn Glu Lys Met Val Lys Leu Lys Arg Glu
                 170                 175                 180

 Lys Asn Ser Arg Asp Gln Asn Phe Val Ile Leu Glu Phe Pro Val
                 185                 190                 195

 Glu Glu Gln Asp Arg Val Leu Ser Phe Arg Cys Gln Ala Arg Ile
                 200                 205                 210

 Ile Ser Gly Ile His Met Gln Thr Ser Glu Ser Thr Lys Ser Glu
                 215                 220                 225

 Leu Val Thr Val Thr Glu Ser Phe Ser Thr Pro Lys Phe His Ile
                 230                 235                 240

 Ser Pro Thr Gly Met Ile Met Glu Gly Ala Gln Leu His Ile Lys
                 245                 250                 255

 Cys Thr Ile Gln Val Thr His Leu Ala Gln Glu Phe Pro Glu Ile
                 260                 265                 270

 Ile Ile Gln Lys Asp Lys Ala Ile Val Ala His Asn Arg His Gly
                 275                 280                 285

 Asn Lys Ala Val Tyr Ser Val Met Ala Met Val Glu His Ser Gly
                 290                 295                 300

 Asn Tyr Thr Cys Lys Val Glu Ser Ser Arg Ile Ser Lys Val Ser
                 305                 310                 315

 Ser Ile Val Val Asn Ile Thr Glu Leu Phe Ser Lys Pro Glu Leu
                 320                 325                 330

 Glu Ser Ser Phe Thr His Leu Asp Gln Gly Glu Arg Leu Asn Leu
                 335                 340                 345

 Ser Cys Ser Ile Pro Gly Ala Pro Pro Ala Asn Phe Thr Ile Gln
                 350                 355                 360

 Lys Glu Asp Thr Ile Val Ser Gln Thr Gln Asp Phe Thr Lys Ile
                 365                 370                 375

 Ala Ser Lys Ser Asp Ser Gly Thr Tyr Ile Cys Thr Ala Gly Ile
                 380                 385                 390

 Asp Lys Val Val Lys Lys Ser Asn Thr Val Gln Ile Val Val Cys
                 395                 400                 405

 Glu Met Leu Ser Gln Pro Arg Ile Ser Tyr Asp Ala Gln Phe Glu
                 410                 415                 420

 Val Ile Lys Gly Gln Thr Ile Glu Val Arg Cys Glu Ser Ile Ser
                 425                 430                 435

 Gly Thr Leu Pro Ile Ser Tyr Gln Leu Leu Lys Thr Ser Lys Val
                 440                 445                 450

 Leu Glu Asn Ser Thr Lys Asn Ser Asn Asp Pro Ala Val Phe Lys
                 455                 460                 465

 Asp Asn Pro Thr Glu Asp Val Glu Tyr Gln Cys Val Ala Asp Asn
                 470                 475                 480

 Cys His Ser His Ala Lys Met Leu Ser Glu Val Leu Arg Val Lys
                 485                 490                 495

 Val Ile Ala Pro Val Asp Glu Val Gln Ile Ser Ile Leu Ser Ser
                 500                 505                 510

 Lys Val Val Glu Ser Gly Glu Asp Ile Val Leu Gln Cys Ala Val
                 515                 520                 525

 Asn Glu Gly Ser Gly Pro Ile Thr Tyr Lys Phe Tyr Arg Glu Lys
                 530                 535                 540

 Glu Gly Lys Pro Phe Tyr Gln Met Thr Ser Asn Ala Thr Gln Ala
                 545                 550                 555

 Phe Trp Thr Lys Gln Lys Ala Ser Lys Glu Gln Glu Gly Glu Tyr
                 560                 565                 570

 Tyr Cys Thr Ala Phe Asn Arg Ala Asn His Ala Ser Ser Val Pro
                 575                 580                 585

 Arg Ser Lys Ile Leu Thr Val Arg Val Ile Leu Ala Pro Trp Lys
                 590                 595                 600

 Lys Gly Leu Ile Ala Val Val Ile Ile Gly Val Ile Ile Ala Leu
                 605                 610                 615

 Leu Ile Ile Ala Ala Lys Cys Tyr Phe Leu Arg Lys Ala Lys Ala
                 620                 625                 630

 Lys Gln Met Pro Val Glu Met Ser Arg Pro Ala Val Pro Leu Leu
                 635                 640                 645

 Asn Ser Asn Asn Glu Lys Met Ser Asp Pro Asn Met Glu Ala Asn
                 650                 655                 660

 Ser His Tyr Gly His Asn Asp Asp Val Arg Asn His Ala Met Lys
                 665                 670                 675

 Pro Ile Asn Asp Asn Lys Glu Pro Leu Asn Ser Asp Val Gln Tyr
                 680                 685                 690

 Thr Glu Val Gln Val Ser Ser Ala Glu Ser His Lys Asp Leu Gly
                 695                 700                 705

 Lys Lys Asp Thr Glu Thr Val Tyr Ser Glu Val Arg Lys Ala Val
                 710                 715                 720

 Pro Asp Ala Val Glu Ser Arg Tyr Ser Arg Thr Glu Gly Ser Leu
                 725                 730                 735

 Asp Gly Thr


<210> 5291
<211> 15359
<212> DNA
<213> Homo sapien

<400> 5291
 tctacctcgc gggtgcctct ggtgtctcca gaggtctccg accccagccc 50

 gcccccagcc ctcccgccca gcccgcagcc ccctccctct gttccccgac 100

 ctcagaccct gggcttccga cctcgacatc atgggtgacg cagaaggcga 150

 agacgaggtc cagttcctgc ggacggacga tgaggtggtc ctgcagtgca 200

 gcgctaccgt gctcaaggag cagctcaagc tctgcctggc cgccgagggc 250

 ttcggcaacc gcctgtgctt cctggagccc actagcaacg cgcagaatgt 300

 gccccccgat ctggccatct gttgcttcgt cctggagcag tccctgtctg 350

 tgcgagccct gcaggagatg ctggctaaca cggtggaggc tggcgtggag 400

 tcatcccagg gcgggggaca caggacgctc ctgtatggcc atgccatcct 450

 gctccggcat gcacacagcc gcatgtatct gagctgcctc accacctccc 500

 gctccatgac tgacaagctg gccttcgatg tgggactgca ggaggacgca 550

 acaggagagg cttgctggtg gaccatgcac ccagcctcca agcagaggtc 600

 tgaaggagaa aaggtccgcg ttggggatga catcatcctt gtcagtgtct 650

 cctccgagcg ctacctgcac ctgtcgaccg ccagtgggga gctccaggtt 700

 gacgcttcct tcatgcagac actgtggaac atgaacccca tctgctcccg 750

 ctgcgaagag ggcttcgtga cgggaggtca cgtcctccgc ctctttcatg 800

 gacatatgga tgagtgtctg accatttccc ctgctgacag tgatgaccag 850

 cgcagacttg tctactatga ggggggagct gtgtgcactc atgcccgctc 900

 cctctggagg ctggagccac tgagaatcag ctggagtggg agccacctgc 950

 gctggggcca gccactccga gtccggcatg tcactaccgg gcagtaccta 1000

 gcgctcaccg aggaccaggg cctggtggtg gttgacgcca gcaaggctca 1050

 caccaaggct acctccttct gcttccgcat ctccaaggag aagctggatg 1100

 tggcccccaa gcgggatgtg gagggcatgg gcccccctga gatcaagtac 1150

 ggggagtcac tgtgcttcgt gcagcatgtg gcctcaggac tgtggctcac 1200

 ctatgccgct ccagacccca aggccctgcg gctcggcgtg ctcaagaaga 1250

 aggccatgct gcaccaggag ggccacatgg acgacgcact gtcgctgacc 1300

 cgctgccagc aggaggagtc ccaggccgcc cgcatgatcc acagcaccaa 1350

 tggcctatac aaccagttca tcaagagcct ggacagcttc agcgggaagc 1400

 cacggggctc ggggccaccc gctggcacgg cgctgcccat cgagggcgtt 1450

 atcctgagcc tgcaggacct catcatctac ttcgagcctc cctccgagga 1500

 cttgcagcac gaggagaagc agagcaagct gcgaagcctg cgcaaccgcc 1550

 agagcctctt ccaggaggag gggatgctct ccatggtcct gaattgcata 1600

 gaccgcctaa atgtctacac cactgctgcc cactttgctg agtttgcagg 1650

 ggaggaggca gccgagtcct ggaaagagat tgtgaatctt ctctatgaac 1700

 tcctagcttc tctaatccgt ggcaatcgta gcaactgtgc cctcttctcc 1750

 acaaacttgg actggctggt cagcaagctg gatcggctgg aggcctcgtc 1800

 tggcatcctg gaggtcctgt actgtgtcct cattgagagt ccagaggttc 1850

 tgaacatcat ccaggagaat cacatcaagt ccatcatctc cctcctggac 1900

 aagcatggga ggaaccacaa ggtcctggac gtgctatgct ccctgtgtgt 1950

 gtgtaatggt gtggctgtac gctccaacca agatcttatt actgagaact 2000

 tgctgcctgg ccgtgagctt ctgctgcaga caaacctcat caactatgtc 2050

 accagcatcc gccccaacat ctttgtgggc cgagcggaag gcaccacgca 2100

 gtacagcaaa tggtactttg aggtgatggt ggacgaggtg actccatttc 2150

 tgacagctca ggccacccac ttgcgggtgg gctgggccct caccgagggc 2200

 tacaccccct accctggggc cggcgagggc tggggcggca acggggtcgg 2250

 cgatgacctc tattcctacg gctttgatgg actgcatctc tggacaggac 2300

 acgtggcacg cccagtgact tccccagggc agcacctcct ggcccctgaa 2350

 gacgtgatca gctgctgcct ggacctcagc gtgccgtcca tctccttccg 2400

 catcaacggc tgccctgtgc agggtgtctt tgagtccttc aacctggacg 2450

 ggctcttctt ccctgttgtc agcttctcgg ctggtgtcaa ggtgcggttc 2500

 ctccttggtg gccgccatgg tgaattcaag ttcctgcccc cacctggcta 2550

 tgctccatgc catgaggctg tgctccctcg agagcgactc catcttgaac 2600

 ccatcaagga gtatcgacgg gaggggcccc gggggcctca cctggtgggc 2650

 cccagtcgct gcctctcaca caccgacttc gtgccctgcc ctgtggacac 2700

 tgtccagatt gtcctgccgc cccatctgga gcgcattcgg gagaagctgg 2750

 cggagaacat ccacgagctc tgggcgctaa cccgcatcga gcagggctgg 2800

 acctacggcc cggttcggga tgacaacaag aggctgcacc cgtgtcttgt 2850

 ggacttccac agccttccag agcctgagag gaactacaac ctgcagatgt 2900

 ctggggagac gctcaagact ctgctggctc tgggctgcca cgtgggcatg 2950

 gcggatgaga aggcggagga caacctgaag aagacaaaac tccccaagac 3000

 gtatatgatg agcaatgggt acaagccggc tccgctggac ctgagccacg 3050

 tgcggctgac gccggcgcag acaacactgg tggaccgtct ggcagaaaat 3100

 gggcacaacg tgtgggcccg agaccgcgtg ggccagggct ggagctacag 3150

 cgcagtgcag gacatcccag cgcgccgaaa ccctcggctg gtgccctacc 3200

 gcctgctgga tgaagccacc aagcgcagca accgggacag cctctgccag 3250

 gccgtgcgca ccctcctggg ctacggctac aacatcgagc ctcctgacca 3300

 ggagcccagt caggtggaga accagtctcg ttgtgaccgg gtgcgcatct 3350

 tccgggcaga gaaatcctat acagtgcaga gcggccgctg gtacttcgag 3400

 tttgaagcag tcaccacagg cgagatgcgc gtgggctggg cgaggcccga 3450

 gctgaggcct gatgtagagc tgggagctga cgagctggcc tatgtcttca 3500

 atgggcaccg cggccagcgc tggcacttgg gcagtgaacc atttgggcgc 3550

 ccctggcagc cgggcgatgt cgttggctgt atgatcgacc tcacagagaa 3600

 caccattatc ttcaccctca atggcgaggt cctcatgtct gactcaggct 3650

 ccgaaacagc cttccgggag attgagattg gggacggctt cctgcccgtc 3700

 tgcagcttgg gacctggcca ggtgggtcat ctgaacctgg gccaggacgt 3750

 gagctctctg aggttctttg ccatctgtgg cctccaggaa ggcttcgagc 3800

 catttgccat caacatgcag cgcccagtca ccacctggtt cagcaaaggc 3850

 ctgccccagt ttgagccagt gccccttgaa caccctcact atgaggtatc 3900

 ccgagtggac ggcactgtgg acacgccccc ctgcctgcgc ctgacccacc 3950

 gcacctgggg ctcccagaac agcctggtgg agatgctttt cctgcggctg 4000

 agcctcccag tccagttcca ccagcacttc cgctgcactg caggggccac 4050

 cccgctggca cctcctggcc tgcagccccc cgccgaggac gaggcccggg 4100

 cggcggaacc cgaccctgac tacgaaaacc tgcgccgctc agctgggggc 4150

 tggagcgagg cagagaacgg caaagaaggg actgcgaagg agggcgcccc 4200

 cgggggcacc ccgcaggcgg ggggagaggc gcagcccgcc agggcggaga 4250

 atgagaagga tgccaccacc gagaagaaca agaagagagg cttcttattc 4300

 aaggccaaga aggtcgccat gatgacccag ccaccggcca cccccacgct 4350

 gccccgactc cctcacgacg tggtgcctgc agacaaccgc gatgaccccg 4400

 agatcatcct caacaccacc acgtactatt actccgtgag ggtctttgct 4450

 ggacaggagc ccagctgcgt gtgggcgggc tgggtcaccc ctgactacca 4500

 tcagcacgac atgagcttcg acctcagcaa ggtccgggtc gtgacggtga 4550

 ccatggggga tgaacaaggc aacgtccaca gcagcctcaa gtgtagcaac 4600

 tgctacatgg tgtggggcgg agactttgtg agtcccgggc agcagggccg 4650

 gatcagccac acggaccttg tcattgggtg cctggtggac ttggccactg 4700

 gcttaatgac ctttacagcc aatggcaaag agagcaacac ctttttccag 4750

 gtggaaccca acactaagct atttcctgcc gtcttcgtcc tgcccaccca 4800

 ccagaacgtc atccagtttg agctggggaa gcagaagaac atcatgccgt 4850

 tgtcagccgc catgttccaa agcgagcgca agaacccggc cccgcagtgc 4900

 ccaccgcggc tggagatgca gatgctgatg ccagtgtcct ggagccgcat 4950

 gcccaaccac ttcctgcagg tggagacgag gcgtgccggc gagcggctgg 5000

 gctgggccgt gcagtgccag gagccgctga ccatgatggc gctgcacatc 5050

 cccgaggaga accggtgcat ggacatcctg gagctgtcgg agcgcctgga 5100

 cctgcagcgc ttccactcgc acaccctgcg cctctaccgc gctgtgtgcg 5150

 ccctgggcaa caatcgcgtg gcgcacgctc tgtgcagcca cgtagaccaa 5200

 gctcagctgc tgcacgccct ggaggacgcg cacctgccag gcccactgcg 5250

 cgcaggctac tatgacctcc tcatcagcat ccacctcgaa agtgcctgcc 5300

 gcagccgccg ctccatgctc tctgaataca tcgtgcccct cacgcctgag 5350

 acccgcgcca tcacgctctt ccctcctgga aggagcacag aaaatggtca 5400

 cccccggcat ggcctgccgg gagttggagt caccacttcg ctgaggcccc 5450

 cgcatcattt ctcgcccccc tgtttcgtgg ccgctctgcc agctgctggg 5500

 gcagcagagg ccccggcccg cctcagccct gccatcccgc tggaggccct 5550

 gcgggacaag gcactgagga tgctggggga ggcggtgcgc gacggtgggc 5600

 agcacgctcg cgaccccgtc ggggcctccg tggagttcca gtttgtgcct 5650

 gtgctcaagc tcgtgtccac cctgctggtg atgggcatct ttggcgatga 5700

 ggatgtgaaa cagatcttga agatgattga gcctgaggtc ttcactgagg 5750

 aagaggagga ggaggacgag gaggaagagg gtgaagagga agatgaggag 5800

 gagaaggagg aggatgagga ggaaacagca caggaaaagg aagatgagga 5850

 aaaagaggaa gaggaggcag cagaagggga gaaagaagaa ggcttggagg 5900

 aagggctgct ccagatgaag ttgccagagt ctgtgaagtt acagatgtgc 5950

 cacctgctgg agtatttctg tgaccaagag ctgcagcacc gtgtggagtc 6000

 cctggcagcc tttgcggagc gctatgtgga caagctccag gccaaccagc 6050

 ggagccgcta tggcctcctc ataaaagcct tcagcatgac cgcagcagag 6100

 actgcaagac gtacccgtga gttccgctcc ccaccccagg aacagatcaa 6150

 tatgctattg caattcaaag atggtacaga tgaggaagac tgtcctctcc 6200

 ctgaagagat tcgacaggat ttgcttgact ttcatcaaga cctgctggca 6250

 cactgtggaa ttcagctaga tggagaggag gaggaaccag aggaagagac 6300

 caccctgggc agccgcctca tgagcctgtt ggagaaagtg cggctggtga 6350

 agaagaagga agagaaacct gaggaggagc ggtcagcaga ggagagcaaa 6400

 ccccggtccc tgcaggagct ggtgtcccac atggtggtgc gctgggccca 6450

 agaggacttc gtgcagagcc ccgagctggt gcgggccatg ttcagcctcc 6500

 tgcaccggca gtacgacggg ctgggtgagc tgctgcgtgc cctgccgcgg 6550

 gcgtacacca tctcaccgtc ctccgtggaa gacaccatga gcctgctcga 6600

 gtgcctcggc cagatccgct cgctgctcat cgtgcagatg ggcccccagg 6650

 aggagaacct catgatccag agcatcggga acatcatgaa caacaaagtc 6700

 ttctaccaac acccgaacct gatgagggcg ctgggcatgc acgagacggt 6750

 catggaggtc atggtcaacg tcctcggggg cggcgagtcc aaggagatcc 6800

 gcttccccaa gatggtgaca agctgctgcc gcttcctctg ctatttctgc 6850

 cgaatcagcc ggcagaacca gcgctccatg tttgaccacc tgagctacct 6900

 gctggagaac agtggcatcg gcctgggcat gcagggctcc acgcccctgg 6950

 acgtggctgc tgcctccgtc attgacaaca atgagctggc cttggcattg 7000

 caggagcagg acctggaaaa ggttgtgtcc tacctggcag gctgtggcct 7050

 ccagagctgc cccatgcttg tggccaaagg gtacccagac attggctgga 7100

 acccctgtgg tggagagcgc tacctggact tcctgcgctt tgctgtcttc 7150

 gtcaacggcg agagcgtgga ggagaacgcc aatgtggtgg tgcggctgct 7200

 catccggaag cctgagtgct tcggacccgc cctgcggggt gagggtggct 7250

 cagggctgct ggctgccatc gaagaggcca tccgcatctc cgaggaccct 7300

 gcgagggatg gcccaggcat ccgcagggac cggcggcgcg agcactttgg 7350

 tgaggaaccg cctgaagaaa accgggtgca cctgggacac gccatcatgt 7400

 ccttctatgc cgccttgatc gacctgctcg gacgctgtgc accagagatg 7450

 catctaatcc aagccggcaa gggtgaggcc ctgcggatcc gcgccatcct 7500

 ccgctccctt gtgcccttgg aggaccttgt gggcatcatc agcctcccac 7550

 tgcagattcc caccctgggc aaagatgggg ctctggtgca gccaaagatg 7600

 tcagcatcct tcgtgccgga ccacaaggcg tccatggtgc tcttcctgga 7650

 ccgtgtgtat ggcatcgaga accaggactt cttgctgcac gtgctggacg 7700

 tggggttcct gcccgacatg agggcagccg cctcgctgga cacggccact 7750

 ttcagcacca ccgagatggc gctggccgtg aaccgctacc tgtgcctggc 7800

 cgtgctgccg ctcatcacca agtgtgcgcc gctctttgcg ggcacagaac 7850

 accgcgccat catggtggac tctatgctgc ataccgtgta ccgcctgtct 7900

 cggggtcgtt cgctcaccaa ggcgcagcgt gacgtcatcg aggactgcct 7950

 catgtcgctc tgcaggtaca tccgcccgtc gatgctgcag cacctgttgc 8000

 gccgcctggt gttcgacgtg cccatcctca acgagttcgc caagatgcca 8050

 ctcaagctcc tcaccaacca ctatgagcgc tgttggaagt actactgcct 8100

 acccacgggc tgggccaact tcggggtcac ctcagaggag gagctgcacc 8150

 tcacacggaa actcttctgg ggcatctttg actctctggc ccataagaaa 8200

 tacgacccgg agctgtaccg catggccatg ccttgtctgt gcgccattgc 8250

 cggggctctg ccccccgact atgtggatgc ctcatactca tctaaggcag 8300

 agaaaaaggc cacagtggat gctgaaggca actttgatcc ccggcctgtg 8350

 gagaccctca atgtgatcat cccggagaag ctggactcct tcattaacaa 8400

 gtttgcggag tacacacacg agaagtgggc cttcgacaag atccagaaca 8450

 actggtccta tggagagaac atagacgagg agctgaagac ccaccccatg 8500

 ctgaggccct acaagacctt ttcagagaag gacaaagaga tttaccgctg 8550

 gcccatcaag gagtccctga aggccatgat tgcctgggaa tggacgatag 8600

 agaaggccag ggagggtgag gaggagaaga cggaaaagaa aaaaacgcgg 8650

 aagatatcac aaagtgccca gacctatgat cctcgagaag gctacaaccc 8700

 tcagcccccc gaccttagtg ctgttaccct gtcccgggag ctgcaggcca 8750

 tggcagaaca actggcagaa aattaccaca acacgtgggg acggaagaag 8800

 aagcaggagc tggaagccaa aggcggtggg acccaccccc tgctggtccc 8850

 ctacgacacg ctcacggcca aggagaaggc acgagatcga gagaaggccc 8900

 aggagctact gaaattcctg cagatgaatg gctacgcggt tacaagaggc 8950

 cttaaggaca tggaactgga ctcgtcttcc attgaaaagc ggtttgcctt 9000

 tggcttcctg cagcagctgc tgcgctggat ggacatttct caggagttca 9050

 ttgcccacct ggaggctgtg gtcagcagtg ggcgagtgga aaagtcccca 9100

 catgaacagg agattaaatt ctttgccaag atcctgctcc ctttgatcaa 9150

 ccagtacttc accaaccact gcctctattt cttgtccact ccggctaaag 9200

 tgctgggcag cggtggccac gcctctaaca aggagaagga aatgatcacc 9250

 agcctcttct gcaaacttgc tgctctcgtc cgccaccgag tctctctctt 9300

 tgggacagac gccccagctg tggtcaactg tcttcacatc ctggcccgct 9350

 ccctggatgc caggacagtg atgaagtcag gccctgagat cgtgaaggct 9400

 ggcctccgct ccttcttcga gagtgcctcg gaggacatcg agaagatggt 9450

 ggagaacctg cggctgggca aggtgtcgca ggcgcgcacc caggtgaaag 9500

 gcgtgggcca gaacctcacc tacaccactg tggcactgct gccggtcctc 9550

 accaccctct tccagcacat cgcccagcac cagttcggag atgacgtcat 9600

 cctggacgac gtccaggtct cttgctaccg aacgctgtgc agtatctact 9650

 ccctgggaac caccaagaac acttatgtgg aaaagcttcg gccagccctc 9700

 ggggagtgcc tggcccgtct ggcagcagcc atgccggtgg cgttcctgga 9750

 gccgcagctg aacgagtaca acgcctgctc cgtgtacacc accaagtctc 9800

 cgcgggagcg ggccatcctg gggctcccca acagtgtgga ggagatgtgt 9850

 cccgacatcc cggtgctgga gcggctcatg gcagacattg gggggctggc 9900

 cgagtcaggt gcccgctaca cagagatgcc gcatgtcatc gagatcacgc 9950

 tgcccatgct atgcagctac ctgccccgat ggtgggagcg cgggcccgag 10000

 gcaccccctt ccgccctgcc cgccggcgcc cccccaccct gcacagctgt 10050

 cacctctgac cacctcaact ccctgctggg gaatatcctg agaatcatcg 10100

 tcaacaacct gggcattgac gaggcctcct ggatgaagcg gctggctgtg 10150

 ttcgcacagc ccattgtgag ccgtgcacgg ccggagctcc tgcagtccca 10200

 cttcatccca actatcgggc ggctgcgcaa gagggcaggg aaggtggtgt 10250

 ccgaggagga gcagctgcgc ctggaggcca aggcggaggc ccaggagggc 10300

 gagctgctgg tgcgggacga gttctctgtg ctctgccggg acctctacgc 10350

 cctgtatccg ctgctcatcc gctacgtgga caacaacagg gcgcagtggc 10400

 tgacggagcc gaatcccagc gcggaggagc tgttcaggat ggtgggcgag 10450

 atcttcatct actggtccaa gtcccacaac ttcaagcgcg aggagcagaa 10500

 ctttgtggtc cagaatgaga tcaacaacat gtccttcctg actgctgaca 10550

 acaaaagcaa aatggctaag gcgggagata tacagtccgg tggctcggac 10600

 caggaacgca ccaagaagaa gcgccggggg gaccggtact ctgtgcagac 10650

 gtcactgatc gtggccacac tgaagaagat gctgcccatc ggcctgaata 10700

 tgtgtgcgcc caccgaccaa gacctcatca cgctggccaa gacccgttac 10750

 gccctgaaag acacagatga ggaggtccgg gaatttctgc acaacaacct 10800

 tcaccttcag ggaaaggtcg aaggctcccc gtctctgcgc tggcagatgg 10850

 ctctgtaccg gggcgtcccg ggtcgcgagg aggacgccga tgaccccgag 10900

 aaaatcgtgc gcagagtcca ggaagtgtca gccgtgctct actacctgga 10950

 ccagaccgag cacccttaca agtctaagaa ggccgtgtgg cacaagcttt 11000

 tgtccaaaca gcgccggcgg gcagtcgtgg cctgtttccg tatgacgccc 11050

 ctgtacaacc tgcccacgca ccgggcatgt aacatgttcc tggagagcta 11100

 caaggctgca tggatcctga ctgaagacca cagttttgag gaccgcatga 11150

 tagatgacct ttcaaaagct ggggagcagg aggaggagga ggaagaggtg 11200

 gaagagaaga agccagaccc cctgcaccag ttggtcctgc acttcagccg 11250

 cactgccctg acggaaaaga gcaaactgga tgaggattac ctgtacatgg 11300

 cctatgctga tatcatggca aagagctgcc acctggagga gggaggggag 11350

 aacggtgaag ctgaagagga ggttgaggtc tcctttgagg agaaacagat 11400

 ggagaagcag aggctcttgt accagcaagc acggctgcac acccgggggg 11450

 cggccgagat ggtgctgcag atgatcagtg cctgcaaagg agagacaggt 11500

 gccatggtgt cctccaccct gaagctgggc atctccatcc tcaatggagg 11550

 caatgctgag gtccagcaga aaatgctgga ttatcttaag gacaagaagg 11600

 aagttggctt cttccagagt atccaggcac tgatgcaaac atgcagcgtc 11650

 ctggatctca atgcctttga gagacaaaac aaggccgagg ggctgggcat 11700

 ggtgaatgag gatggcactg tcatcaatcg ccagaacgga gagaaggtca 11750

 tggcggatga tgaattcaca caagacctgt tccgattcct acaattgctc 11800

 tgtgaggggc acaataatga tttccagaac tacctacgga cacagacagg 11850

 gaacacgacc actattaaca tcatcatttg cactgtggac tacctcctgc 11900

 ggctgcagga atccatcagc gacttctact ggtactactc gggcaaggat 11950

 gtcattgaag agcagggcaa gaggaacttc tccaaagcca tgtcggtggc 12000

 taagcaggtg ttcaacagcc tcactgagta catccagggt ccctgcaccg 12050

 ggaaccagca gagcctggcg cacagtcgcc tatgggacgc agtggtggga 12100

 ttcctgcacg tgttcgccca catgatgatg aagctcgctc aggactcaag 12150

 ccagatcgag ctgctgaagg agctgctgga tctgcagaag gacatggtgg 12200

 tgatgttgct gtcgctacta gaagggaacg tggtgaacgg catgatcgcc 12250

 cggcagatgg tggacatgct cgtggaatcc tcatccaatg tggagatgat 12300

 cctcaagttc ttcgacatgt tcctgaaact caaggacatt gtgggctctg 12350

 aagccttcca ggactacgta acggatcccc gtggcctcat ctccaagaag 12400

 gacttccaga aggccatgga cagccagaag cagttcagcg gtccagaaat 12450

 ccagttcctg ctttcgtgct ccgaagcgga tgagaacgaa atgatcaact 12500

 gcgaagagtt cgccaaccgc ttccaggagc cagcacgcga catcggcttc 12550

 aacgtggcgg tgctgctgac caacctgtcg gagcatgtgc cgcatgaccc 12600

 tcgcctgcac aacttcctgg agctggccga gagcatcctt gagtacttcc 12650

 gcccctacct gggccgcatc gagatcatgg gcgcgtcacg ccgcatcgag 12700

 cgcatctact tcgagatctc agagaccaac cgcgcccagt gggagatgcc 12750

 ccaggtgaag gagtccaagc gccagttcat cttcgacgtg gtgaacgagg 12800

 gcggcgaggc tgagaagatg gagctcttcg tgagtttctg cgaggacacc 12850

 atcttcgaga tgcagatcgc cgcgcagatc tcggagcccg agggcgagcc 12900

 ggagaccgac gaggacgagg gcgcgggcgc ggcggaggcg ggcgcggaag 12950

 gcgcggagga gggcgcggcg gggctcgagg gcacggcggc cacggcggcg 13000

 gcgggggcga cggcgcgggt tgtggcggcc gcaggccggg ccctgcgagg 13050

 cctcagctac cgcagcctgc ggcggcgcgt gcggcggctg cggcggctta 13100

 cggcccgcga ggcggccacc gcagtggcgg cgctgctctg ggcagcagtg 13150

 acgcgcgctg gggccgctgg cgcgggggcg gcggcgggcg cgctgggcct 13200

 gctctggggc tcgctgttcg gcggcggcct ggtggagggc gccaagaagg 13250

 tgacggtgac cgagctcctg gcaggcatgc ccgaccccac cagcgacgag 13300

 gtgcacggcg agcagccggc cgggccgggc ggagacgcag acggcgaggg 13350

 tgccagcgag ggcgctggag acgccgcgga gggcgctgga gacgaggagg 13400

 aggcggtgca cgaggccggg ccgggcggtg ccgacggggc ggtggccgtg 13450

 accgatgggg gccccttccg gcccgaaggg gctggcggtc tcggggacat 13500

 gggggacacg acgcctgcgg aaccgcccac acccgagggc tctcccatcc 13550

 tcaagaggaa attgggggtg gatggagtgg aggaggagct cccgccagag 13600

 ccagagcccg agccggaacc agagctggag ccggagaaag ccgatgccga 13650

 gaatggggag aaggaagaag ttcccgagcc cacaccagag ccccccaaga 13700

 agcaagcacc tccctcaccc cctccaaaga aggaggaagc tggaggcgaa 13750

 ttctggggag aactggaggt gcagagggtg aagttcctga actacctgtc 13800

 ccggaacttt tacaccctgc ggttccttgc cctcttcttg gcatttgcca 13850

 tcaacttcat cttgctgttt tataaggtct cagactctcc accaggggag 13900

 gacgacatgg aaggctcagc tgctggggat gtgtcaggtg caggctctgg 13950

 tggcagctct ggctggggct tgggggccgg agaggaggca gagggcgatg 14000

 aggatgagaa catggtgtac tacttcctgg aggaaagcac aggctacatg 14050

 gaacccgccc tgcggtgtct gagcctcctg catacactgg tggcctttct 14100

 ctgcatcatt ggctataatt gtctcaaggt gcccctggta atctttaagc 14150

 gggagaagga gctggcccgg aagctggagt ttgatggcct gtacatcacg 14200

 gagcagcctg aggacgatga cgtgaagggg cagtgggacc gactggtgct 14250

 caacacgccg tctttcccta gcaactactg ggacaagttt gtcaagcgca 14300

 aggtcctgga caaacatggg gacatctacg ggcgggagcg gattgctgag 14350

 ctactgggca tggacctggc cacactagag atcacagccc acaatgagcg 14400

 caagcccaac ccgccgccag ggctgctgac ctggctcatg tccatcgatg 14450

 tcaagtacca gatctggaag ttcggggtca tcttcacaga caactccttc 14500

 ctgtacctgg gctggtatat ggtgatgtcc ctcttgggac actacaacaa 14550

 cttcttcttt gctgcccatc tcctggacat cgccatgggg gtcaagacgc 14600

 tgcgcaccat cctgtcctct gtcacccaca atgggaaaca gctggtgatg 14650

 accgtgggcc ttctggcggt ggtcgtctac ctgtacaccg tggtggcctt 14700

 caacttcttc cgcaagttct acaacaagag cgaggatgag gatgaacctg 14750

 acatgaagtg tgatgacatg atgacgtgtt acctgtttca catgtacgtg 14800

 ggtgtccggg ctggcggagg cattggggac gagatcgagg accccgcggg 14850

 tgacgaatac gagctctaca gggtggtctt cgacatcacc ttcttcttct 14900

 tcgtcatcgt catcctgttg gccatcatcc agggtctgat catcgacgct 14950

 tttggtgagc tccgagacca acaagagcaa gtgaaggagg atatggagac 15000

 caagtgcttc atctgtggaa tcggcagtga ctactttgat acgacaccgc 15050

 atggcttcga gactcacacg ctggaggagc acaacctggc caattacatg 15100

 tttttcctga tgtatttgat aaacaaggat gagacagaac acacgggtca 15150

 ggagtcttat gtctggaaga tgtaccaaga gagatgttgg gatttcttcc 15200

 cagctggtga ttgtttccgt aagcagtatg aggaccagct tagctgacac 15250

 acccccagct ggccctccac ccccacctca agtgccttat tctcacagca 15300

 agccccttag tccccaagcc cctcccccta aggcagctgg gggagaggtg 15350

 acctagtac 15359

<210> 5292
<211> 5038
<212> PRT
<213> Homo sapien

<400> 5292
 Met Gly Asp Ala Glu Gly Glu Asp Glu Val Gln Phe Leu Arg Thr
   1               5                  10                  15

 Asp Asp Glu Val Val Leu Gln Cys Ser Ala Thr Val Leu Lys Glu
                  20                  25                  30

 Gln Leu Lys Leu Cys Leu Ala Ala Glu Gly Phe Gly Asn Arg Leu
                  35                  40                  45

 Cys Phe Leu Glu Pro Thr Ser Asn Ala Gln Asn Val Pro Pro Asp
                  50                  55                  60

 Leu Ala Ile Cys Cys Phe Val Leu Glu Gln Ser Leu Ser Val Arg
                  65                  70                  75

 Ala Leu Gln Glu Met Leu Ala Asn Thr Val Glu Ala Gly Val Glu
                  80                  85                  90

 Ser Ser Gln Gly Gly Gly His Arg Thr Leu Leu Tyr Gly His Ala
                  95                 100                 105

 Ile Leu Leu Arg His Ala His Ser Arg Met Tyr Leu Ser Cys Leu
                 110                 115                 120

 Thr Thr Ser Arg Ser Met Thr Asp Lys Leu Ala Phe Asp Val Gly
                 125                 130                 135

 Leu Gln Glu Asp Ala Thr Gly Glu Ala Cys Trp Trp Thr Met His
                 140                 145                 150

 Pro Ala Ser Lys Gln Arg Ser Glu Gly Glu Lys Val Arg Val Gly
                 155                 160                 165

 Asp Asp Ile Ile Leu Val Ser Val Ser Ser Glu Arg Tyr Leu His
                 170                 175                 180

 Leu Ser Thr Ala Ser Gly Glu Leu Gln Val Asp Ala Ser Phe Met
                 185                 190                 195

 Gln Thr Leu Trp Asn Met Asn Pro Ile Cys Ser Arg Cys Glu Glu
                 200                 205                 210

 Gly Phe Val Thr Gly Gly His Val Leu Arg Leu Phe His Gly His
                 215                 220                 225

 Met Asp Glu Cys Leu Thr Ile Ser Pro Ala Asp Ser Asp Asp Gln
                 230                 235                 240

 Arg Arg Leu Val Tyr Tyr Glu Gly Gly Ala Val Cys Thr His Ala
                 245                 250                 255

 Arg Ser Leu Trp Arg Leu Glu Pro Leu Arg Ile Ser Trp Ser Gly
                 260                 265                 270

 Ser His Leu Arg Trp Gly Gln Pro Leu Arg Val Arg His Val Thr
                 275                 280                 285

 Thr Gly Gln Tyr Leu Ala Leu Thr Glu Asp Gln Gly Leu Val Val
                 290                 295                 300

 Val Asp Ala Ser Lys Ala His Thr Lys Ala Thr Ser Phe Cys Phe
                 305                 310                 315

 Arg Ile Ser Lys Glu Lys Leu Asp Val Ala Pro Lys Arg Asp Val
                 320                 325                 330

 Glu Gly Met Gly Pro Pro Glu Ile Lys Tyr Gly Glu Ser Leu Cys
                 335                 340                 345

 Phe Val Gln His Val Ala Ser Gly Leu Trp Leu Thr Tyr Ala Ala
                 350                 355                 360

 Pro Asp Pro Lys Ala Leu Arg Leu Gly Val Leu Lys Lys Lys Ala
                 365                 370                 375

 Met Leu His Gln Glu Gly His Met Asp Asp Ala Leu Ser Leu Thr
                 380                 385                 390

 Arg Cys Gln Gln Glu Glu Ser Gln Ala Ala Arg Met Ile His Ser
                 395                 400                 405

 Thr Asn Gly Leu Tyr Asn Gln Phe Ile Lys Ser Leu Asp Ser Phe
                 410                 415                 420

 Ser Gly Lys Pro Arg Gly Ser Gly Pro Pro Ala Gly Thr Ala Leu
                 425                 430                 435

 Pro Ile Glu Gly Val Ile Leu Ser Leu Gln Asp Leu Ile Ile Tyr
                 440                 445                 450

 Phe Glu Pro Pro Ser Glu Asp Leu Gln His Glu Glu Lys Gln Ser
                 455                 460                 465

 Lys Leu Arg Ser Leu Arg Asn Arg Gln Ser Leu Phe Gln Glu Glu
                 470                 475                 480

 Gly Met Leu Ser Met Val Leu Asn Cys Ile Asp Arg Leu Asn Val
                 485                 490                 495

 Tyr Thr Thr Ala Ala His Phe Ala Glu Phe Ala Gly Glu Glu Ala
                 500                 505                 510

 Ala Glu Ser Trp Lys Glu Ile Val Asn Leu Leu Tyr Glu Leu Leu
                 515                 520                 525

 Ala Ser Leu Ile Arg Gly Asn Arg Ser Asn Cys Ala Leu Phe Ser
                 530                 535                 540

 Thr Asn Leu Asp Trp Leu Val Ser Lys Leu Asp Arg Leu Glu Ala
                 545                 550                 555

 Ser Ser Gly Ile Leu Glu Val Leu Tyr Cys Val Leu Ile Glu Ser
                 560                 565                 570

 Pro Glu Val Leu Asn Ile Ile Gln Glu Asn His Ile Lys Ser Ile
                 575                 580                 585

 Ile Ser Leu Leu Asp Lys His Gly Arg Asn His Lys Val Leu Asp
                 590                 595                 600

 Val Leu Cys Ser Leu Cys Val Cys Asn Gly Val Ala Val Arg Ser
                 605                 610                 615

 Asn Gln Asp Leu Ile Thr Glu Asn Leu Leu Pro Gly Arg Glu Leu
                 620                 625                 630

 Leu Leu Gln Thr Asn Leu Ile Asn Tyr Val Thr Ser Ile Arg Pro
                 635                 640                 645

 Asn Ile Phe Val Gly Arg Ala Glu Gly Thr Thr Gln Tyr Ser Lys
                 650                 655                 660

 Trp Tyr Phe Glu Val Met Val Asp Glu Val Thr Pro Phe Leu Thr
                 665                 670                 675

 Ala Gln Ala Thr His Leu Arg Val Gly Trp Ala Leu Thr Glu Gly
                 680                 685                 690

 Tyr Thr Pro Tyr Pro Gly Ala Gly Glu Gly Trp Gly Gly Asn Gly
                 695                 700                 705

 Val Gly Asp Asp Leu Tyr Ser Tyr Gly Phe Asp Gly Leu His Leu
                 710                 715                 720

 Trp Thr Gly His Val Ala Arg Pro Val Thr Ser Pro Gly Gln His
                 725                 730                 735

 Leu Leu Ala Pro Glu Asp Val Ile Ser Cys Cys Leu Asp Leu Ser
                 740                 745                 750

 Val Pro Ser Ile Ser Phe Arg Ile Asn Gly Cys Pro Val Gln Gly
                 755                 760                 765

 Val Phe Glu Ser Phe Asn Leu Asp Gly Leu Phe Phe Pro Val Val
                 770                 775                 780

 Ser Phe Ser Ala Gly Val Lys Val Arg Phe Leu Leu Gly Gly Arg
                 785                 790                 795

 His Gly Glu Phe Lys Phe Leu Pro Pro Pro Gly Tyr Ala Pro Cys
                 800                 805                 810

 His Glu Ala Val Leu Pro Arg Glu Arg Leu His Leu Glu Pro Ile
                 815                 820                 825

 Lys Glu Tyr Arg Arg Glu Gly Pro Arg Gly Pro His Leu Val Gly
                 830                 835                 840

 Pro Ser Arg Cys Leu Ser His Thr Asp Phe Val Pro Cys Pro Val
                 845                 850                 855

 Asp Thr Val Gln Ile Val Leu Pro Pro His Leu Glu Arg Ile Arg
                 860                 865                 870

 Glu Lys Leu Ala Glu Asn Ile His Glu Leu Trp Ala Leu Thr Arg
                 875                 880                 885

 Ile Glu Gln Gly Trp Thr Tyr Gly Pro Val Arg Asp Asp Asn Lys
                 890                 895                 900

 Arg Leu His Pro Cys Leu Val Asp Phe His Ser Leu Pro Glu Pro
                 905                 910                 915

 Glu Arg Asn Tyr Asn Leu Gln Met Ser Gly Glu Thr Leu Lys Thr
                 920                 925                 930

 Leu Leu Ala Leu Gly Cys His Val Gly Met Ala Asp Glu Lys Ala
                 935                 940                 945

 Glu Asp Asn Leu Lys Lys Thr Lys Leu Pro Lys Thr Tyr Met Met
                 950                 955                 960

 Ser Asn Gly Tyr Lys Pro Ala Pro Leu Asp Leu Ser His Val Arg
                 965                 970                 975

 Leu Thr Pro Ala Gln Thr Thr Leu Val Asp Arg Leu Ala Glu Asn
                 980                 985                 990

 Gly His Asn Val Trp Ala Arg Asp Arg Val Gly Gln Gly Trp Ser
                 995                1000                1005

 Tyr Ser Ala Val Gln Asp Ile Pro Ala Arg Arg Asn Pro Arg Leu
                1010                1015                1020

 Val Pro Tyr Arg Leu Leu Asp Glu Ala Thr Lys Arg Ser Asn Arg
                1025                1030                1035

 Asp Ser Leu Cys Gln Ala Val Arg Thr Leu Leu Gly Tyr Gly Tyr
                1040                1045                1050

 Asn Ile Glu Pro Pro Asp Gln Glu Pro Ser Gln Val Glu Asn Gln
                1055                1060                1065

 Ser Arg Cys Asp Arg Val Arg Ile Phe Arg Ala Glu Lys Ser Tyr
                1070                1075                1080

 Thr Val Gln Ser Gly Arg Trp Tyr Phe Glu Phe Glu Ala Val Thr
                1085                1090                1095

 Thr Gly Glu Met Arg Val Gly Trp Ala Arg Pro Glu Leu Arg Pro
                1100                1105                1110

 Asp Val Glu Leu Gly Ala Asp Glu Leu Ala Tyr Val Phe Asn Gly
                1115                1120                1125

 His Arg Gly Gln Arg Trp His Leu Gly Ser Glu Pro Phe Gly Arg
                1130                1135                1140

 Pro Trp Gln Pro Gly Asp Val Val Gly Cys Met Ile Asp Leu Thr
                1145                1150                1155

 Glu Asn Thr Ile Ile Phe Thr Leu Asn Gly Glu Val Leu Met Ser
                1160                1165                1170

 Asp Ser Gly Ser Glu Thr Ala Phe Arg Glu Ile Glu Ile Gly Asp
                1175                1180                1185

 Gly Phe Leu Pro Val Cys Ser Leu Gly Pro Gly Gln Val Gly His
                1190                1195                1200

 Leu Asn Leu Gly Gln Asp Val Ser Ser Leu Arg Phe Phe Ala Ile
                1205                1210                1215

 Cys Gly Leu Gln Glu Gly Phe Glu Pro Phe Ala Ile Asn Met Gln
                1220                1225                1230

 Arg Pro Val Thr Thr Trp Phe Ser Lys Gly Leu Pro Gln Phe Glu
                1235                1240                1245

 Pro Val Pro Leu Glu His Pro His Tyr Glu Val Ser Arg Val Asp
                1250                1255                1260

 Gly Thr Val Asp Thr Pro Pro Cys Leu Arg Leu Thr His Arg Thr
                1265                1270                1275

 Trp Gly Ser Gln Asn Ser Leu Val Glu Met Leu Phe Leu Arg Leu
                1280                1285                1290

 Ser Leu Pro Val Gln Phe His Gln His Phe Arg Cys Thr Ala Gly
                1295                1300                1305

 Ala Thr Pro Leu Ala Pro Pro Gly Leu Gln Pro Pro Ala Glu Asp
                1310                1315                1320

 Glu Ala Arg Ala Ala Glu Pro Asp Pro Asp Tyr Glu Asn Leu Arg
                1325                1330                1335

 Arg Ser Ala Gly Gly Trp Ser Glu Ala Glu Asn Gly Lys Glu Gly
                1340                1345                1350

 Thr Ala Lys Glu Gly Ala Pro Gly Gly Thr Pro Gln Ala Gly Gly
                1355                1360                1365

 Glu Ala Gln Pro Ala Arg Ala Glu Asn Glu Lys Asp Ala Thr Thr
                1370                1375                1380

 Glu Lys Asn Lys Lys Arg Gly Phe Leu Phe Lys Ala Lys Lys Val
                1385                1390                1395

 Ala Met Met Thr Gln Pro Pro Ala Thr Pro Thr Leu Pro Arg Leu
                1400                1405                1410

 Pro His Asp Val Val Pro Ala Asp Asn Arg Asp Asp Pro Glu Ile
                1415                1420                1425

 Ile Leu Asn Thr Thr Thr Tyr Tyr Tyr Ser Val Arg Val Phe Ala
                1430                1435                1440

 Gly Gln Glu Pro Ser Cys Val Trp Ala Gly Trp Val Thr Pro Asp
                1445                1450                1455

 Tyr His Gln His Asp Met Ser Phe Asp Leu Ser Lys Val Arg Val
                1460                1465                1470

 Val Thr Val Thr Met Gly Asp Glu Gln Gly Asn Val His Ser Ser
                1475                1480                1485

 Leu Lys Cys Ser Asn Cys Tyr Met Val Trp Gly Gly Asp Phe Val
                1490                1495                1500

 Ser Pro Gly Gln Gln Gly Arg Ile Ser His Thr Asp Leu Val Ile
                1505                1510                1515

 Gly Cys Leu Val Asp Leu Ala Thr Gly Leu Met Thr Phe Thr Ala
                1520                1525                1530

 Asn Gly Lys Glu Ser Asn Thr Phe Phe Gln Val Glu Pro Asn Thr
                1535                1540                1545

 Lys Leu Phe Pro Ala Val Phe Val Leu Pro Thr His Gln Asn Val
                1550                1555                1560

 Ile Gln Phe Glu Leu Gly Lys Gln Lys Asn Ile Met Pro Leu Ser
                1565                1570                1575

 Ala Ala Met Phe Gln Ser Glu Arg Lys Asn Pro Ala Pro Gln Cys
                1580                1585                1590

 Pro Pro Arg Leu Glu Met Gln Met Leu Met Pro Val Ser Trp Ser
                1595                1600                1605

 Arg Met Pro Asn His Phe Leu Gln Val Glu Thr Arg Arg Ala Gly
                1610                1615                1620

 Glu Arg Leu Gly Trp Ala Val Gln Cys Gln Glu Pro Leu Thr Met
                1625                1630                1635

 Met Ala Leu His Ile Pro Glu Glu Asn Arg Cys Met Asp Ile Leu
                1640                1645                1650

 Glu Leu Ser Glu Arg Leu Asp Leu Gln Arg Phe His Ser His Thr
                1655                1660                1665

 Leu Arg Leu Tyr Arg Ala Val Cys Ala Leu Gly Asn Asn Arg Val
                1670                1675                1680

 Ala His Ala Leu Cys Ser His Val Asp Gln Ala Gln Leu Leu His
                1685                1690                1695

 Ala Leu Glu Asp Ala His Leu Pro Gly Pro Leu Arg Ala Gly Tyr
                1700                1705                1710

 Tyr Asp Leu Leu Ile Ser Ile His Leu Glu Ser Ala Cys Arg Ser
                1715                1720                1725

 Arg Arg Ser Met Leu Ser Glu Tyr Ile Val Pro Leu Thr Pro Glu
                1730                1735                1740

 Thr Arg Ala Ile Thr Leu Phe Pro Pro Gly Arg Ser Thr Glu Asn
                1745                1750                1755

 Gly His Pro Arg His Gly Leu Pro Gly Val Gly Val Thr Thr Ser
                1760                1765                1770

 Leu Arg Pro Pro His His Phe Ser Pro Pro Cys Phe Val Ala Ala
                1775                1780                1785

 Leu Pro Ala Ala Gly Ala Ala Glu Ala Pro Ala Arg Leu Ser Pro
                1790                1795                1800

 Ala Ile Pro Leu Glu Ala Leu Arg Asp Lys Ala Leu Arg Met Leu
                1805                1810                1815

 Gly Glu Ala Val Arg Asp Gly Gly Gln His Ala Arg Asp Pro Val
                1820                1825                1830

 Gly Ala Ser Val Glu Phe Gln Phe Val Pro Val Leu Lys Leu Val
                1835                1840                1845

 Ser Thr Leu Leu Val Met Gly Ile Phe Gly Asp Glu Asp Val Lys
                1850                1855                1860

 Gln Ile Leu Lys Met Ile Glu Pro Glu Val Phe Thr Glu Glu Glu
                1865                1870                1875

 Glu Glu Glu Asp Glu Glu Glu Glu Gly Glu Glu Glu Asp Glu Glu
                1880                1885                1890

 Glu Lys Glu Glu Asp Glu Glu Glu Thr Ala Gln Glu Lys Glu Asp
                1895                1900                1905

 Glu Glu Lys Glu Glu Glu Glu Ala Ala Glu Gly Glu Lys Glu Glu
                1910                1915                1920

 Gly Leu Glu Glu Gly Leu Leu Gln Met Lys Leu Pro Glu Ser Val
                1925                1930                1935

 Lys Leu Gln Met Cys His Leu Leu Glu Tyr Phe Cys Asp Gln Glu
                1940                1945                1950

 Leu Gln His Arg Val Glu Ser Leu Ala Ala Phe Ala Glu Arg Tyr
                1955                1960                1965

 Val Asp Lys Leu Gln Ala Asn Gln Arg Ser Arg Tyr Gly Leu Leu
                1970                1975                1980

 Ile Lys Ala Phe Ser Met Thr Ala Ala Glu Thr Ala Arg Arg Thr
                1985                1990                1995

 Arg Glu Phe Arg Ser Pro Pro Gln Glu Gln Ile Asn Met Leu Leu
                2000                2005                2010

 Gln Phe Lys Asp Gly Thr Asp Glu Glu Asp Cys Pro Leu Pro Glu
                2015                2020                2025

 Glu Ile Arg Gln Asp Leu Leu Asp Phe His Gln Asp Leu Leu Ala
                2030                2035                2040

 His Cys Gly Ile Gln Leu Asp Gly Glu Glu Glu Glu Pro Glu Glu
                2045                2050                2055

 Glu Thr Thr Leu Gly Ser Arg Leu Met Ser Leu Leu Glu Lys Val
                2060                2065                2070

 Arg Leu Val Lys Lys Lys Glu Glu Lys Pro Glu Glu Glu Arg Ser
                2075                2080                2085

 Ala Glu Glu Ser Lys Pro Arg Ser Leu Gln Glu Leu Val Ser His
                2090                2095                2100

 Met Val Val Arg Trp Ala Gln Glu Asp Phe Val Gln Ser Pro Glu
                2105                2110                2115

 Leu Val Arg Ala Met Phe Ser Leu Leu His Arg Gln Tyr Asp Gly
                2120                2125                2130

 Leu Gly Glu Leu Leu Arg Ala Leu Pro Arg Ala Tyr Thr Ile Ser
                2135                2140                2145

 Pro Ser Ser Val Glu Asp Thr Met Ser Leu Leu Glu Cys Leu Gly
                2150                2155                2160

 Gln Ile Arg Ser Leu Leu Ile Val Gln Met Gly Pro Gln Glu Glu
                2165                2170                2175

 Asn Leu Met Ile Gln Ser Ile Gly Asn Ile Met Asn Asn Lys Val
                2180                2185                2190

 Phe Tyr Gln His Pro Asn Leu Met Arg Ala Leu Gly Met His Glu
                2195                2200                2205

 Thr Val Met Glu Val Met Val Asn Val Leu Gly Gly Gly Glu Ser
                2210                2215                2220

 Lys Glu Ile Arg Phe Pro Lys Met Val Thr Ser Cys Cys Arg Phe
                2225                2230                2235

 Leu Cys Tyr Phe Cys Arg Ile Ser Arg Gln Asn Gln Arg Ser Met
                2240                2245                2250

 Phe Asp His Leu Ser Tyr Leu Leu Glu Asn Ser Gly Ile Gly Leu
                2255                2260                2265

 Gly Met Gln Gly Ser Thr Pro Leu Asp Val Ala Ala Ala Ser Val
                2270                2275                2280

 Ile Asp Asn Asn Glu Leu Ala Leu Ala Leu Gln Glu Gln Asp Leu
                2285                2290                2295

 Glu Lys Val Val Ser Tyr Leu Ala Gly Cys Gly Leu Gln Ser Cys
                2300                2305                2310

 Pro Met Leu Val Ala Lys Gly Tyr Pro Asp Ile Gly Trp Asn Pro
                2315                2320                2325

 Cys Gly Gly Glu Arg Tyr Leu Asp Phe Leu Arg Phe Ala Val Phe
                2330                2335                2340

 Val Asn Gly Glu Ser Val Glu Glu Asn Ala Asn Val Val Val Arg
                2345                2350                2355

 Leu Leu Ile Arg Lys Pro Glu Cys Phe Gly Pro Ala Leu Arg Gly
                2360                2365                2370

 Glu Gly Gly Ser Gly Leu Leu Ala Ala Ile Glu Glu Ala Ile Arg
                2375                2380                2385

 Ile Ser Glu Asp Pro Ala Arg Asp Gly Pro Gly Ile Arg Arg Asp
                2390                2395                2400

 Arg Arg Arg Glu His Phe Gly Glu Glu Pro Pro Glu Glu Asn Arg
                2405                2410                2415

 Val His Leu Gly His Ala Ile Met Ser Phe Tyr Ala Ala Leu Ile
                2420                2425                2430

 Asp Leu Leu Gly Arg Cys Ala Pro Glu Met His Leu Ile Gln Ala
                2435                2440                2445

 Gly Lys Gly Glu Ala Leu Arg Ile Arg Ala Ile Leu Arg Ser Leu
                2450                2455                2460

 Val Pro Leu Glu Asp Leu Val Gly Ile Ile Ser Leu Pro Leu Gln
                2465                2470                2475

 Ile Pro Thr Leu Gly Lys Asp Gly Ala Leu Val Gln Pro Lys Met
                2480                2485                2490

 Ser Ala Ser Phe Val Pro Asp His Lys Ala Ser Met Val Leu Phe
                2495                2500                2505

 Leu Asp Arg Val Tyr Gly Ile Glu Asn Gln Asp Phe Leu Leu His
                2510                2515                2520

 Val Leu Asp Val Gly Phe Leu Pro Asp Met Arg Ala Ala Ala Ser
                2525                2530                2535

 Leu Asp Thr Ala Thr Phe Ser Thr Thr Glu Met Ala Leu Ala Val
                2540                2545                2550

 Asn Arg Tyr Leu Cys Leu Ala Val Leu Pro Leu Ile Thr Lys Cys
                2555                2560                2565

 Ala Pro Leu Phe Ala Gly Thr Glu His Arg Ala Ile Met Val Asp
                2570                2575                2580

 Ser Met Leu His Thr Val Tyr Arg Leu Ser Arg Gly Arg Ser Leu
                2585                2590                2595

 Thr Lys Ala Gln Arg Asp Val Ile Glu Asp Cys Leu Met Ser Leu
                2600                2605                2610

 Cys Arg Tyr Ile Arg Pro Ser Met Leu Gln His Leu Leu Arg Arg
                2615                2620                2625

 Leu Val Phe Asp Val Pro Ile Leu Asn Glu Phe Ala Lys Met Pro
                2630                2635                2640

 Leu Lys Leu Leu Thr Asn His Tyr Glu Arg Cys Trp Lys Tyr Tyr
                2645                2650                2655

 Cys Leu Pro Thr Gly Trp Ala Asn Phe Gly Val Thr Ser Glu Glu
                2660                2665                2670

 Glu Leu His Leu Thr Arg Lys Leu Phe Trp Gly Ile Phe Asp Ser
                2675                2680                2685

 Leu Ala His Lys Lys Tyr Asp Pro Glu Leu Tyr Arg Met Ala Met
                2690                2695                2700

 Pro Cys Leu Cys Ala Ile Ala Gly Ala Leu Pro Pro Asp Tyr Val
                2705                2710                2715

 Asp Ala Ser Tyr Ser Ser Lys Ala Glu Lys Lys Ala Thr Val Asp
                2720                2725                2730

 Ala Glu Gly Asn Phe Asp Pro Arg Pro Val Glu Thr Leu Asn Val
                2735                2740                2745

 Ile Ile Pro Glu Lys Leu Asp Ser Phe Ile Asn Lys Phe Ala Glu
                2750                2755                2760

 Tyr Thr His Glu Lys Trp Ala Phe Asp Lys Ile Gln Asn Asn Trp
                2765                2770                2775

 Ser Tyr Gly Glu Asn Ile Asp Glu Glu Leu Lys Thr His Pro Met
                2780                2785                2790

 Leu Arg Pro Tyr Lys Thr Phe Ser Glu Lys Asp Lys Glu Ile Tyr
                2795                2800                2805

 Arg Trp Pro Ile Lys Glu Ser Leu Lys Ala Met Ile Ala Trp Glu
                2810                2815                2820

 Trp Thr Ile Glu Lys Ala Arg Glu Gly Glu Glu Glu Lys Thr Glu
                2825                2830                2835

 Lys Lys Lys Thr Arg Lys Ile Ser Gln Ser Ala Gln Thr Tyr Asp
                2840                2845                2850

 Pro Arg Glu Gly Tyr Asn Pro Gln Pro Pro Asp Leu Ser Ala Val
                2855                2860                2865

 Thr Leu Ser Arg Glu Leu Gln Ala Met Ala Glu Gln Leu Ala Glu
                2870                2875                2880

 Asn Tyr His Asn Thr Trp Gly Arg Lys Lys Lys Gln Glu Leu Glu
                2885                2890                2895

 Ala Lys Gly Gly Gly Thr His Pro Leu Leu Val Pro Tyr Asp Thr
                2900                2905                2910

 Leu Thr Ala Lys Glu Lys Ala Arg Asp Arg Glu Lys Ala Gln Glu
                2915                2920                2925

 Leu Leu Lys Phe Leu Gln Met Asn Gly Tyr Ala Val Thr Arg Gly
                2930                2935                2940

 Leu Lys Asp Met Glu Leu Asp Ser Ser Ser Ile Glu Lys Arg Phe
                2945                2950                2955

 Ala Phe Gly Phe Leu Gln Gln Leu Leu Arg Trp Met Asp Ile Ser
                2960                2965                2970

 Gln Glu Phe Ile Ala His Leu Glu Ala Val Val Ser Ser Gly Arg
                2975                2980                2985

 Val Glu Lys Ser Pro His Glu Gln Glu Ile Lys Phe Phe Ala Lys
                2990                2995                3000

 Ile Leu Leu Pro Leu Ile Asn Gln Tyr Phe Thr Asn His Cys Leu
                3005                3010                3015

 Tyr Phe Leu Ser Thr Pro Ala Lys Val Leu Gly Ser Gly Gly His
                3020                3025                3030

 Ala Ser Asn Lys Glu Lys Glu Met Ile Thr Ser Leu Phe Cys Lys
                3035                3040                3045

 Leu Ala Ala Leu Val Arg His Arg Val Ser Leu Phe Gly Thr Asp
                3050                3055                3060

 Ala Pro Ala Val Val Asn Cys Leu His Ile Leu Ala Arg Ser Leu
                3065                3070                3075

 Asp Ala Arg Thr Val Met Lys Ser Gly Pro Glu Ile Val Lys Ala
                3080                3085                3090

 Gly Leu Arg Ser Phe Phe Glu Ser Ala Ser Glu Asp Ile Glu Lys
                3095                3100                3105

 Met Val Glu Asn Leu Arg Leu Gly Lys Val Ser Gln Ala Arg Thr
                3110                3115                3120

 Gln Val Lys Gly Val Gly Gln Asn Leu Thr Tyr Thr Thr Val Ala
                3125                3130                3135

 Leu Leu Pro Val Leu Thr Thr Leu Phe Gln His Ile Ala Gln His
                3140                3145                3150

 Gln Phe Gly Asp Asp Val Ile Leu Asp Asp Val Gln Val Ser Cys
                3155                3160                3165

 Tyr Arg Thr Leu Cys Ser Ile Tyr Ser Leu Gly Thr Thr Lys Asn
                3170                3175                3180

 Thr Tyr Val Glu Lys Leu Arg Pro Ala Leu Gly Glu Cys Leu Ala
                3185                3190                3195

 Arg Leu Ala Ala Ala Met Pro Val Ala Phe Leu Glu Pro Gln Leu
                3200                3205                3210

 Asn Glu Tyr Asn Ala Cys Ser Val Tyr Thr Thr Lys Ser Pro Arg
                3215                3220                3225

 Glu Arg Ala Ile Leu Gly Leu Pro Asn Ser Val Glu Glu Met Cys
                3230                3235                3240

 Pro Asp Ile Pro Val Leu Glu Arg Leu Met Ala Asp Ile Gly Gly
                3245                3250                3255

 Leu Ala Glu Ser Gly Ala Arg Tyr Thr Glu Met Pro His Val Ile
                3260                3265                3270

 Glu Ile Thr Leu Pro Met Leu Cys Ser Tyr Leu Pro Arg Trp Trp
                3275                3280                3285

 Glu Arg Gly Pro Glu Ala Pro Pro Ser Ala Leu Pro Ala Gly Ala
                3290                3295                3300

 Pro Pro Pro Cys Thr Ala Val Thr Ser Asp His Leu Asn Ser Leu
                3305                3310                3315

 Leu Gly Asn Ile Leu Arg Ile Ile Val Asn Asn Leu Gly Ile Asp
                3320                3325                3330

 Glu Ala Ser Trp Met Lys Arg Leu Ala Val Phe Ala Gln Pro Ile
                3335                3340                3345

 Val Ser Arg Ala Arg Pro Glu Leu Leu Gln Ser His Phe Ile Pro
                3350                3355                3360

 Thr Ile Gly Arg Leu Arg Lys Arg Ala Gly Lys Val Val Ser Glu
                3365                3370                3375

 Glu Glu Gln Leu Arg Leu Glu Ala Lys Ala Glu Ala Gln Glu Gly
                3380                3385                3390

 Glu Leu Leu Val Arg Asp Glu Phe Ser Val Leu Cys Arg Asp Leu
                3395                3400                3405

 Tyr Ala Leu Tyr Pro Leu Leu Ile Arg Tyr Val Asp Asn Asn Arg
                3410                3415                3420

 Ala Gln Trp Leu Thr Glu Pro Asn Pro Ser Ala Glu Glu Leu Phe
                3425                3430                3435

 Arg Met Val Gly Glu Ile Phe Ile Tyr Trp Ser Lys Ser His Asn
                3440                3445                3450

 Phe Lys Arg Glu Glu Gln Asn Phe Val Val Gln Asn Glu Ile Asn
                3455                3460                3465

 Asn Met Ser Phe Leu Thr Ala Asp Asn Lys Ser Lys Met Ala Lys
                3470                3475                3480

 Ala Gly Asp Ile Gln Ser Gly Gly Ser Asp Gln Glu Arg Thr Lys
                3485                3490                3495

 Lys Lys Arg Arg Gly Asp Arg Tyr Ser Val Gln Thr Ser Leu Ile
                3500                3505                3510

 Val Ala Thr Leu Lys Lys Met Leu Pro Ile Gly Leu Asn Met Cys
                3515                3520                3525

 Ala Pro Thr Asp Gln Asp Leu Ile Thr Leu Ala Lys Thr Arg Tyr
                3530                3535                3540

 Ala Leu Lys Asp Thr Asp Glu Glu Val Arg Glu Phe Leu His Asn
                3545                3550                3555

 Asn Leu His Leu Gln Gly Lys Val Glu Gly Ser Pro Ser Leu Arg
                3560                3565                3570

 Trp Gln Met Ala Leu Tyr Arg Gly Val Pro Gly Arg Glu Glu Asp
                3575                3580                3585

 Ala Asp Asp Pro Glu Lys Ile Val Arg Arg Val Gln Glu Val Ser
                3590                3595                3600

 Ala Val Leu Tyr Tyr Leu Asp Gln Thr Glu His Pro Tyr Lys Ser
                3605                3610                3615

 Lys Lys Ala Val Trp His Lys Leu Leu Ser Lys Gln Arg Arg Arg
                3620                3625                3630

 Ala Val Val Ala Cys Phe Arg Met Thr Pro Leu Tyr Asn Leu Pro
                3635                3640                3645

 Thr His Arg Ala Cys Asn Met Phe Leu Glu Ser Tyr Lys Ala Ala
                3650                3655                3660

 Trp Ile Leu Thr Glu Asp His Ser Phe Glu Asp Arg Met Ile Asp
                3665                3670                3675

 Asp Leu Ser Lys Ala Gly Glu Gln Glu Glu Glu Glu Glu Glu Val
                3680                3685                3690

 Glu Glu Lys Lys Pro Asp Pro Leu His Gln Leu Val Leu His Phe
                3695                3700                3705

 Ser Arg Thr Ala Leu Thr Glu Lys Ser Lys Leu Asp Glu Asp Tyr
                3710                3715                3720

 Leu Tyr Met Ala Tyr Ala Asp Ile Met Ala Lys Ser Cys His Leu
                3725                3730                3735

 Glu Glu Gly Gly Glu Asn Gly Glu Ala Glu Glu Glu Val Glu Val
                3740                3745                3750

 Ser Phe Glu Glu Lys Gln Met Glu Lys Gln Arg Leu Leu Tyr Gln
                3755                3760                3765

 Gln Ala Arg Leu His Thr Arg Gly Ala Ala Glu Met Val Leu Gln
                3770                3775                3780

 Met Ile Ser Ala Cys Lys Gly Glu Thr Gly Ala Met Val Ser Ser
                3785                3790                3795

 Thr Leu Lys Leu Gly Ile Ser Ile Leu Asn Gly Gly Asn Ala Glu
                3800                3805                3810

 Val Gln Gln Lys Met Leu Asp Tyr Leu Lys Asp Lys Lys Glu Val
                3815                3820                3825

 Gly Phe Phe Gln Ser Ile Gln Ala Leu Met Gln Thr Cys Ser Val
                3830                3835                3840

 Leu Asp Leu Asn Ala Phe Glu Arg Gln Asn Lys Ala Glu Gly Leu
                3845                3850                3855

 Gly Met Val Asn Glu Asp Gly Thr Val Ile Asn Arg Gln Asn Gly
                3860                3865                3870

 Glu Lys Val Met Ala Asp Asp Glu Phe Thr Gln Asp Leu Phe Arg
                3875                3880                3885

 Phe Leu Gln Leu Leu Cys Glu Gly His Asn Asn Asp Phe Gln Asn
                3890                3895                3900

 Tyr Leu Arg Thr Gln Thr Gly Asn Thr Thr Thr Ile Asn Ile Ile
                3905                3910                3915

 Ile Cys Thr Val Asp Tyr Leu Leu Arg Leu Gln Glu Ser Ile Ser
                3920                3925                3930

 Asp Phe Tyr Trp Tyr Tyr Ser Gly Lys Asp Val Ile Glu Glu Gln
                3935                3940                3945

 Gly Lys Arg Asn Phe Ser Lys Ala Met Ser Val Ala Lys Gln Val
                3950                3955                3960

 Phe Asn Ser Leu Thr Glu Tyr Ile Gln Gly Pro Cys Thr Gly Asn
                3965                3970                3975

 Gln Gln Ser Leu Ala His Ser Arg Leu Trp Asp Ala Val Val Gly
                3980                3985                3990

 Phe Leu His Val Phe Ala His Met Met Met Lys Leu Ala Gln Asp
                3995                4000                4005

 Ser Ser Gln Ile Glu Leu Leu Lys Glu Leu Leu Asp Leu Gln Lys
                4010                4015                4020

 Asp Met Val Val Met Leu Leu Ser Leu Leu Glu Gly Asn Val Val
                4025                4030                4035

 Asn Gly Met Ile Ala Arg Gln Met Val Asp Met Leu Val Glu Ser
                4040                4045                4050

 Ser Ser Asn Val Glu Met Ile Leu Lys Phe Phe Asp Met Phe Leu
                4055                4060                4065

 Lys Leu Lys Asp Ile Val Gly Ser Glu Ala Phe Gln Asp Tyr Val
                4070                4075                4080

 Thr Asp Pro Arg Gly Leu Ile Ser Lys Lys Asp Phe Gln Lys Ala
                4085                4090                4095

 Met Asp Ser Gln Lys Gln Phe Ser Gly Pro Glu Ile Gln Phe Leu
                4100                4105                4110

 Leu Ser Cys Ser Glu Ala Asp Glu Asn Glu Met Ile Asn Cys Glu
                4115                4120                4125

 Glu Phe Ala Asn Arg Phe Gln Glu Pro Ala Arg Asp Ile Gly Phe
                4130                4135                4140

 Asn Val Ala Val Leu Leu Thr Asn Leu Ser Glu His Val Pro His
                4145                4150                4155

 Asp Pro Arg Leu His Asn Phe Leu Glu Leu Ala Glu Ser Ile Leu
                4160                4165                4170

 Glu Tyr Phe Arg Pro Tyr Leu Gly Arg Ile Glu Ile Met Gly Ala
                4175                4180                4185

 Ser Arg Arg Ile Glu Arg Ile Tyr Phe Glu Ile Ser Glu Thr Asn
                4190                4195                4200

 Arg Ala Gln Trp Glu Met Pro Gln Val Lys Glu Ser Lys Arg Gln
                4205                4210                4215

 Phe Ile Phe Asp Val Val Asn Glu Gly Gly Glu Ala Glu Lys Met
                4220                4225                4230

 Glu Leu Phe Val Ser Phe Cys Glu Asp Thr Ile Phe Glu Met Gln
                4235                4240                4245

 Ile Ala Ala Gln Ile Ser Glu Pro Glu Gly Glu Pro Glu Thr Asp
                4250                4255                4260

 Glu Asp Glu Gly Ala Gly Ala Ala Glu Ala Gly Ala Glu Gly Ala
                4265                4270                4275

 Glu Glu Gly Ala Ala Gly Leu Glu Gly Thr Ala Ala Thr Ala Ala
                4280                4285                4290

 Ala Gly Ala Thr Ala Arg Val Val Ala Ala Ala Gly Arg Ala Leu
                4295                4300                4305

 Arg Gly Leu Ser Tyr Arg Ser Leu Arg Arg Arg Val Arg Arg Leu
                4310                4315                4320

 Arg Arg Leu Thr Ala Arg Glu Ala Ala Thr Ala Val Ala Ala Leu
                4325                4330                4335

 Leu Trp Ala Ala Val Thr Arg Ala Gly Ala Ala Gly Ala Gly Ala
                4340                4345                4350

 Ala Ala Gly Ala Leu Gly Leu Leu Trp Gly Ser Leu Phe Gly Gly
                4355                4360                4365

 Gly Leu Val Glu Gly Ala Lys Lys Val Thr Val Thr Glu Leu Leu
                4370                4375                4380

 Ala Gly Met Pro Asp Pro Thr Ser Asp Glu Val His Gly Glu Gln
                4385                4390                4395

 Pro Ala Gly Pro Gly Gly Asp Ala Asp Gly Glu Gly Ala Ser Glu
                4400                4405                4410

 Gly Ala Gly Asp Ala Ala Glu Gly Ala Gly Asp Glu Glu Glu Ala
                4415                4420                4425

 Val His Glu Ala Gly Pro Gly Gly Ala Asp Gly Ala Val Ala Val
                4430                4435                4440

 Thr Asp Gly Gly Pro Phe Arg Pro Glu Gly Ala Gly Gly Leu Gly
                4445                4450                4455

 Asp Met Gly Asp Thr Thr Pro Ala Glu Pro Pro Thr Pro Glu Gly
                4460                4465                4470

 Ser Pro Ile Leu Lys Arg Lys Leu Gly Val Asp Gly Val Glu Glu
                4475                4480                4485

 Glu Leu Pro Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Leu Glu
                4490                4495                4500

 Pro Glu Lys Ala Asp Ala Glu Asn Gly Glu Lys Glu Glu Val Pro
                4505                4510                4515

 Glu Pro Thr Pro Glu Pro Pro Lys Lys Gln Ala Pro Pro Ser Pro
                4520                4525                4530

 Pro Pro Lys Lys Glu Glu Ala Gly Gly Glu Phe Trp Gly Glu Leu
                4535                4540                4545

 Glu Val Gln Arg Val Lys Phe Leu Asn Tyr Leu Ser Arg Asn Phe
                4550                4555                4560

 Tyr Thr Leu Arg Phe Leu Ala Leu Phe Leu Ala Phe Ala Ile Asn
                4565                4570                4575

 Phe Ile Leu Leu Phe Tyr Lys Val Ser Asp Ser Pro Pro Gly Glu
                4580                4585                4590

 Asp Asp Met Glu Gly Ser Ala Ala Gly Asp Val Ser Gly Ala Gly
                4595                4600                4605

 Ser Gly Gly Ser Ser Gly Trp Gly Leu Gly Ala Gly Glu Glu Ala
                4610                4615                4620

 Glu Gly Asp Glu Asp Glu Asn Met Val Tyr Tyr Phe Leu Glu Glu
                4625                4630                4635

 Ser Thr Gly Tyr Met Glu Pro Ala Leu Arg Cys Leu Ser Leu Leu
                4640                4645                4650

 His Thr Leu Val Ala Phe Leu Cys Ile Ile Gly Tyr Asn Cys Leu
                4655                4660                4665

 Lys Val Pro Leu Val Ile Phe Lys Arg Glu Lys Glu Leu Ala Arg
                4670                4675                4680

 Lys Leu Glu Phe Asp Gly Leu Tyr Ile Thr Glu Gln Pro Glu Asp
                4685                4690                4695

 Asp Asp Val Lys Gly Gln Trp Asp Arg Leu Val Leu Asn Thr Pro
                4700                4705                4710

 Ser Phe Pro Ser Asn Tyr Trp Asp Lys Phe Val Lys Arg Lys Val
                4715                4720                4725

 Leu Asp Lys His Gly Asp Ile Tyr Gly Arg Glu Arg Ile Ala Glu
                4730                4735                4740

 Leu Leu Gly Met Asp Leu Ala Thr Leu Glu Ile Thr Ala His Asn
                4745                4750                4755

 Glu Arg Lys Pro Asn Pro Pro Pro Gly Leu Leu Thr Trp Leu Met
                4760                4765                4770

 Ser Ile Asp Val Lys Tyr Gln Ile Trp Lys Phe Gly Val Ile Phe
                4775                4780                4785

 Thr Asp Asn Ser Phe Leu Tyr Leu Gly Trp Tyr Met Val Met Ser
                4790                4795                4800

 Leu Leu Gly His Tyr Asn Asn Phe Phe Phe Ala Ala His Leu Leu
                4805                4810                4815

 Asp Ile Ala Met Gly Val Lys Thr Leu Arg Thr Ile Leu Ser Ser
                4820                4825                4830

 Val Thr His Asn Gly Lys Gln Leu Val Met Thr Val Gly Leu Leu
                4835                4840                4845

 Ala Val Val Val Tyr Leu Tyr Thr Val Val Ala Phe Asn Phe Phe
                4850                4855                4860

 Arg Lys Phe Tyr Asn Lys Ser Glu Asp Glu Asp Glu Pro Asp Met
                4865                4870                4875

 Lys Cys Asp Asp Met Met Thr Cys Tyr Leu Phe His Met Tyr Val
                4880                4885                4890

 Gly Val Arg Ala Gly Gly Gly Ile Gly Asp Glu Ile Glu Asp Pro
                4895                4900                4905

 Ala Gly Asp Glu Tyr Glu Leu Tyr Arg Val Val Phe Asp Ile Thr
                4910                4915                4920

 Phe Phe Phe Phe Val Ile Val Ile Leu Leu Ala Ile Ile Gln Gly
                4925                4930                4935

 Leu Ile Ile Asp Ala Phe Gly Glu Leu Arg Asp Gln Gln Glu Gln
                4940                4945                4950

 Val Lys Glu Asp Met Glu Thr Lys Cys Phe Ile Cys Gly Ile Gly
                4955                4960                4965

 Ser Asp Tyr Phe Asp Thr Thr Pro His Gly Phe Glu Thr His Thr
                4970                4975                4980

 Leu Glu Glu His Asn Leu Ala Asn Tyr Met Phe Phe Leu Met Tyr
                4985                4990                4995

 Leu Ile Asn Lys Asp Glu Thr Glu His Thr Gly Gln Glu Ser Tyr
                5000                5005                5010

 Val Trp Lys Met Tyr Gln Glu Arg Cys Trp Asp Phe Phe Pro Ala
                5015                5020                5025

 Gly Asp Cys Phe Arg Lys Gln Tyr Glu Asp Gln Leu Ser
                5030                5035

<210> 5293
<211> 2102
<212> DNA
<213> Homo sapien

<400> 5293
 ccgctgggcg tagctgcgac tcggcggagt cccggcggcg cgtccttgtt 50

 ctaacccggc gcgccatgac cgtcgcgcgg ccgagcgtgc ccgcggcgct 100

 gcccctcctc ggggagctgc cccggctgct gctgctggtg ctgttgtgcc 150

 tgccggccgt gtggggtgac tgtggccttc ccccagatgt acctaatgcc 200

 cagccagctt tggaaggccg tacaagtttt cccgaggata ctgtaataac 250

 gtacaaatgt gaagaaagct ttgtgaaaat tcctggcgag aaggactcag 300

 tgatctgcct taagggcagt caatggtcag atattgaaga gttctgcaat 350

 cgtagctgcg aggtgccaac aaggctaaat tctgcatccc tcaaacagcc 400

 ttatatcact cagaattatt ttccagtcgg tactgttgtg gaatatgagt 450

 gccgtccagg ttacagaaga gaaccttctc tatcaccaaa actaacttgc 500

 cttcagaatt taaaatggtc cacagcagtc gaattttgta aaaagaaatc 550

 atgccctaat ccgggagaaa tacgaaatgg tcagattgat gtaccaggtg 600

 gcatattatt tggtgcaacc atctccttct catgtaacac agggtacaaa 650

 ttatttggct cgacttctag tttttgtctt atttcaggca gctctgtcca 700

 gtggagtgac ccgttgccag agtgcagaga aatttattgt ccagcaccac 750

 cacaaattga caatggaata attcaagggg aacgtgacca ttatggatat 800

 agacagtctg taacgtatgc atgtaataaa ggattcacca tgattggaga 850

 gcactctatt tattgtactg tgaataatga tgaaggagag tggagtggcc 900

 caccacctga atgcagagga aaatctctaa cttccaaggt cccaccaaca 950

 gttcagaaac ctaccacagt aaatgttcca actacagaag tctcaccaac 1000

 ttctcagaaa accaccacaa aaaccaccac accaaatgct caagcaacac 1050

 ggagtacacc tgtttccagg acaaccaagc attttcatga aacaacccca 1100

 aataaaggaa gtggaaccac ttcaggtact acccgtcttc tatctgggca 1150

 cacgtgtttc acgttgacag gtttgcttgg gacgctagta accatgggct 1200

 tgctgactta gccaaagaag agttaagaag aaaatacaca caagtataca 1250

 gactgttcct agtttcttag acttatctgc atattggata aaataaatgc 1300

 aattgtgctc ttcatttagg atgctttcat tgtctttaag atgtgttagg 1350

 aatgtcaaca gagcaaggag aaaaaaggca gtcctggaat cacattctta 1400

 gcacacctac acctcttgaa aatagaacaa cttgcagaat tgagagtgat 1450

 tcctttccta aaagtgtaag aaagcataga gatttgttcg tatttagaat 1500

 gggatcacga ggaaaagaga aggaaagtga tttttttcca caagatctgt 1550

 aatgttattt ccacttataa aggaaataaa aaatgaaaaa cattatttgg 1600

 atatcaaaag caaataaaaa cccaattcag tctcttctaa gcaaaattgc 1650

 taaagagaga tgaaccacat tataaagtaa tctttggctg taaggcattt 1700

 tcatctttcc ttcgggttgg caaaatattt taaaggtaaa acatgctggt 1750

 gaaccagggg tgttgatggt gataagggag gaatatagaa tgaaagactg 1800

 aatcttcctt tgttgcacaa atagagtttg gaaaaagcct gtgaaaggtg 1850

 tcttctttga cttaatgtct ttaaaagtat ccagagatac tacaatatta 1900

 acataagaaa agattatata ttatttctga atcgagatgt ccatagtcaa 1950

 atttgtaaat cttattcttt tgtaatattt atttatattt atttatgaca 2000

 gtgaacattc tgattttaca tgtaaaacaa gaaaagttga agaagatatg 2050

 tgaagaaaaa tgtatttttc ctaaatagaa ataaatgatc ccattttttg 2100

 gt 2102

<210> 5294
<211> 381
<212> PRT
<213> Homo sapien

<400> 5294
 Met Thr Val Ala Arg Pro Ser Val Pro Ala Ala Leu Pro Leu Leu
   1               5                  10                  15

 Gly Glu Leu Pro Arg Leu Leu Leu Leu Val Leu Leu Cys Leu Pro
                  20                  25                  30

 Ala Val Trp Gly Asp Cys Gly Leu Pro Pro Asp Val Pro Asn Ala
                  35                  40                  45

 Gln Pro Ala Leu Glu Gly Arg Thr Ser Phe Pro Glu Asp Thr Val
                  50                  55                  60

 Ile Thr Tyr Lys Cys Glu Glu Ser Phe Val Lys Ile Pro Gly Glu
                  65                  70                  75

 Lys Asp Ser Val Ile Cys Leu Lys Gly Ser Gln Trp Ser Asp Ile
                  80                  85                  90

 Glu Glu Phe Cys Asn Arg Ser Cys Glu Val Pro Thr Arg Leu Asn
                  95                 100                 105

 Ser Ala Ser Leu Lys Gln Pro Tyr Ile Thr Gln Asn Tyr Phe Pro
                 110                 115                 120

 Val Gly Thr Val Val Glu Tyr Glu Cys Arg Pro Gly Tyr Arg Arg
                 125                 130                 135

 Glu Pro Ser Leu Ser Pro Lys Leu Thr Cys Leu Gln Asn Leu Lys
                 140                 145                 150

 Trp Ser Thr Ala Val Glu Phe Cys Lys Lys Lys Ser Cys Pro Asn
                 155                 160                 165

 Pro Gly Glu Ile Arg Asn Gly Gln Ile Asp Val Pro Gly Gly Ile
                 170                 175                 180

 Leu Phe Gly Ala Thr Ile Ser Phe Ser Cys Asn Thr Gly Tyr Lys
                 185                 190                 195

 Leu Phe Gly Ser Thr Ser Ser Phe Cys Leu Ile Ser Gly Ser Ser
                 200                 205                 210

 Val Gln Trp Ser Asp Pro Leu Pro Glu Cys Arg Glu Ile Tyr Cys
                 215                 220                 225

 Pro Ala Pro Pro Gln Ile Asp Asn Gly Ile Ile Gln Gly Glu Arg
                 230                 235                 240

 Asp His Tyr Gly Tyr Arg Gln Ser Val Thr Tyr Ala Cys Asn Lys
                 245                 250                 255

 Gly Phe Thr Met Ile Gly Glu His Ser Ile Tyr Cys Thr Val Asn
                 260                 265                 270

 Asn Asp Glu Gly Glu Trp Ser Gly Pro Pro Pro Glu Cys Arg Gly
                 275                 280                 285

 Lys Ser Leu Thr Ser Lys Val Pro Pro Thr Val Gln Lys Pro Thr
                 290                 295                 300

 Thr Val Asn Val Pro Thr Thr Glu Val Ser Pro Thr Ser Gln Lys
                 305                 310                 315

 Thr Thr Thr Lys Thr Thr Thr Pro Asn Ala Gln Ala Thr Arg Ser
                 320                 325                 330

 Thr Pro Val Ser Arg Thr Thr Lys His Phe His Glu Thr Thr Pro
                 335                 340                 345

 Asn Lys Gly Ser Gly Thr Thr Ser Gly Thr Thr Arg Leu Leu Ser
                 350                 355                 360

 Gly His Thr Cys Phe Thr Leu Thr Gly Leu Leu Gly Thr Leu Val
                 365                 370                 375

 Thr Met Gly Leu Leu Thr
                 380

<210> 5295
<211> 3655
<212> DNA
<213> Homo sapien

<400> 5295
 cttcagatag attatatctg gagtgaagga tcctgccacc tacgtatctg 50

 gcatagtatt ctgtgtagtg ggatgagcag agaacaaaaa caaaataatc 100

 cagtgagaaa agcccgtaaa taaaccttca gaccagagat ctattctcca 150

 gcttatttta agctcaactt aaaaagaaga actgttctct gattcttttc 200

 gccttcaata cacttaatga tttaactcca ccctccttca aaagaaacag 250

 catttcctac ttttatactg tctatatgat tgatttgcac agctcatctg 300

 gccagaagag ctgagacatc cgttccccta caagaaactc tccccgggtg 350

 gaacaagatg gattatcaag tgtcaagtcc aatctatgac atcaattatt 400

 atacatcgga gccctgccaa aaaatcaatg tgaagcaaat cgcagcccgc 450

 ctcctgcctc cgctctactc actggtgttc atctttggtt ttgtgggcaa 500

 catgctggtc atcctcatcc tgataaactg caaaaggctg aagagcatga 550

 ctgacatcta cctgctcaac ctggccatct ctgacctgtt tttccttctt 600

 actgtcccct tctgggctca ctatgctgcc gcccagtggg actttggaaa 650

 tacaatgtgt caactcttga cagggctcta ttttataggc ttcttctctg 700

 gaatcttctt catcatcctc ctgacaatcg ataggtacct ggctgtcgtc 750

 catgctgtgt ttgctttaaa agccaggacg gtcacctttg gggtggtgac 800

 aagtgtgatc acttgggtgg tggctgtgtt tgcgtctctc ccaggaatca 850

 tctttaccag atctcaaaaa gaaggtcttc attacacctg cagctctcat 900

 tttccataca gtcagtatca attctggaag aatttccaga cattaaagat 950

 agtcatcttg gggctggtcc tgccgctgct tgtcatggtc atctgctact 1000

 cgggaatcct aaaaactctg cttcggtgtc gaaatgagaa gaagaggcac 1050

 agggctgtga ggcttatctt caccatcatg attgtttatt ttctcttctg 1100

 ggctccctac aacattgtcc ttctcctgaa caccttccag gaattctttg 1150

 gcctgaataa ttgcagtagc tctaacaggt tggaccaagc tatgcaggtg 1200

 acagagactc ttgggatgac gcactgctgc atcaacccca tcatctatgc 1250

 ctttgtcggg gagaagttca gaaactacct cttagtcttc ttccaaaagc 1300

 acattgccaa acgcttctgc aaatgctgtt ctattttcca gcaagaggct 1350

 cccgagcgag caagctcagt ttacacccga tccactgggg agcaggaaat 1400

 atctgtgggc ttgtgacacg gactcaagtg ggctggtgac ccagtcagag 1450

 ttgtgcacat ggcttagttt tcatacacag cctgggctgg gggtggggtg 1500

 ggagaggtct tttttaaaag gaagttactg ttatagaggg tctaagattc 1550

 atccatttat ttggcatctg tttaaagtag attagatctt ttaagcccat 1600

 caattataga aagccaaatc aaaatatgtt gatgaaaaat agcaaccttt 1650

 ttatctcccc ttcacatgca tcaagttatt gacaaactct cccttcactc 1700

 cgaaagttcc ttatgtatat ttaaaagaaa gcctcagaga attgctgatt 1750

 cttgagttta gtgatctgaa cagaaatacc aaaattattt cagaaatgta 1800

 caacttttta cctagtacaa ggcaacatat aggttgtaaa tgtgtttaaa 1850

 acaggtcttt gtcttgctat ggggagaaaa gacatgaata tgattagtaa 1900

 agaaatgaca cttttcatgt gtgatttccc ctccaaggta tggttaataa 1950

 gtttcactga cttagaacca ggcgagagac ttgtggcctg ggagagctgg 2000

 ggaagcttct taaatgagaa ggaatttgag ttggatcatc tattgctggc 2050

 aaagacagaa gcctcactgc aagcactgca tgggcaagct tggctgtaga 2100

 aggagacaga gctggttggg aagacatggg gaggaaggac aaggctagat 2150

 catgaagaac cttgacggca ttgctccgtc taagtcatga gctgagcagg 2200

 gagatcctgg ttggtgttgc agaaggttta ctctgtggcc aaaggagggt 2250

 caggaaggat gagcatttag ggcaaggaga ccaccaacag ccctcaggtc 2300

 agggtgagga tggcctctgc taagctcaag gcgtgaggat gggaaggagg 2350

 gaggtattcg taaggatggg aaggagggag gtattcgtgc agcatatgag 2400

 gatgcagagt cagcagaact ggggtggatt tggtttggaa gtgagggtca 2450

 gagaggagtc agagagaatc cctagtcttc aagcagattg gagaaaccct 2500

 tgaaaagaca tcaagcacag aaggaggagg aggaggttta ggtcaagaag 2550

 aagatggatt ggtgtaaaag gatgggtctg gtttgcagag cttgaacaca 2600

 gtctcaccca gactccaggc tgtctttcac tgaatgcttc tgacttcata 2650

 gatttccttc ccatcccagc tgaaatactg aggggtctcc aggaggagac 2700

 tagatttatg aatacacgag gtatgaggtc taggaacata cttcagctca 2750

 cacatgagat ctaggtgagg attgattacc tagtagtcat ttcatgggtt 2800

 gttgggagga ttctatgagg caaccacagg cagcatttag cacatactac 2850

 acattcaata agcatcaaac tcttagttac tcattcaggg atagcactga 2900

 gcaaagcatt gagcaaaggg gtcccatata ggtgagggaa gcctgaaaaa 2950

 ctaagatgct gcctgcccag tgcacacaag tgtaggtatc attttctgca 3000

 tttaaccgtc aataggcaaa ggggggaagg gacatattca tttggaaata 3050

 agctgccttg agccttaaaa cccacaaaag tacaatttac cagcctccgt 3100

 atttcagact gaatgggggt ggggggggcg ccttaggtac ttattccaga 3150

 tgccttctcc agacaaacca gaagcaacag aaaaaatcgt ctctccctcc 3200

 ctttgaaatg aatatacccc ttagtgtttg ggtatattca tttcaaaggg 3250

 agagagagag gtttttttct gttctttctc atatgattgt gcacatactt 3300

 gagactgttt tgaatttggg ggatggctaa aaccatcata gtacaggtaa 3350

 ggtgagggaa tagtaagtgg tgagaactac tcagggaatg aaggtgtcag 3400

 aataataaga ggtgctactg actttctcag cctctgaata tgaacggtga 3450

 gcattgtggc tgtcagcagg aagcaacgaa gggaaatgtc tttccttttg 3500

 ctcttaagtt gtggagagtg caacagtagc ataggaccct accctctggg 3550

 ccaagtcaaa gacattctga catcttagta tttgcatatt cttatgtatg 3600

 tgaaagttac aaattgcttg aaagaaaata tgcatctaat aaaaaacacc 3650

 ttcta 3655

<210> 5296
<211> 352
<212> PRT
<213> Homo sapien

<400> 5296
 Met Asp Tyr Gln Val Ser Ser Pro Ile Tyr Asp Ile Asn Tyr Tyr
   1               5                  10                  15

 Thr Ser Glu Pro Cys Gln Lys Ile Asn Val Lys Gln Ile Ala Ala
                  20                  25                  30

 Arg Leu Leu Pro Pro Leu Tyr Ser Leu Val Phe Ile Phe Gly Phe
                  35                  40                  45

 Val Gly Asn Met Leu Val Ile Leu Ile Leu Ile Asn Cys Lys Arg
                  50                  55                  60

 Leu Lys Ser Met Thr Asp Ile Tyr Leu Leu Asn Leu Ala Ile Ser
                  65                  70                  75

 Asp Leu Phe Phe Leu Leu Thr Val Pro Phe Trp Ala His Tyr Ala
                  80                  85                  90

 Ala Ala Gln Trp Asp Phe Gly Asn Thr Met Cys Gln Leu Leu Thr
                  95                 100                 105

 Gly Leu Tyr Phe Ile Gly Phe Phe Ser Gly Ile Phe Phe Ile Ile
                 110                 115                 120

 Leu Leu Thr Ile Asp Arg Tyr Leu Ala Val Val His Ala Val Phe
                 125                 130                 135

 Ala Leu Lys Ala Arg Thr Val Thr Phe Gly Val Val Thr Ser Val
                 140                 145                 150

 Ile Thr Trp Val Val Ala Val Phe Ala Ser Leu Pro Gly Ile Ile
                 155                 160                 165

 Phe Thr Arg Ser Gln Lys Glu Gly Leu His Tyr Thr Cys Ser Ser
                 170                 175                 180

 His Phe Pro Tyr Ser Gln Tyr Gln Phe Trp Lys Asn Phe Gln Thr
                 185                 190                 195

 Leu Lys Ile Val Ile Leu Gly Leu Val Leu Pro Leu Leu Val Met
                 200                 205                 210

 Val Ile Cys Tyr Ser Gly Ile Leu Lys Thr Leu Leu Arg Cys Arg
                 215                 220                 225

 Asn Glu Lys Lys Arg His Arg Ala Val Arg Leu Ile Phe Thr Ile
                 230                 235                 240

 Met Ile Val Tyr Phe Leu Phe Trp Ala Pro Tyr Asn Ile Val Leu
                 245                 250                 255

 Leu Leu Asn Thr Phe Gln Glu Phe Phe Gly Leu Asn Asn Cys Ser
                 260                 265                 270

 Ser Ser Asn Arg Leu Asp Gln Ala Met Gln Val Thr Glu Thr Leu
                 275                 280                 285

 Gly Met Thr His Cys Cys Ile Asn Pro Ile Ile Tyr Ala Phe Val
                 290                 295                 300

 Gly Glu Lys Phe Arg Asn Tyr Leu Leu Val Phe Phe Gln Lys His
                 305                 310                 315

 Ile Ala Lys Arg Phe Cys Lys Cys Cys Ser Ile Phe Gln Gln Glu
                 320                 325                 330

 Ala Pro Glu Arg Ala Ser Ser Val Tyr Thr Arg Ser Thr Gly Glu
                 335                 340                 345

 Gln Glu Ile Ser Val Gly Leu
                 350

<210> 5297
<211> 1666
<212> DNA
<213> Homo sapien

<400> 5297
 ctccataagg cacaaacttt cagagacagc agagcacaca agcttctagg 50

 acaagagcca ggaagaaacc accggaagga accatctcac tgtgtgtaaa 100

 catgacttcc aagctggccg tggctctctt ggcagccttc ctgatttctg 150

 cagctctgtg tgaaggtgca gttttgccaa ggagtgctaa agaacttaga 200

 tgtcagtgca taaagacata ctccaaacct ttccacccca aatttatcaa 250

 agaactgaga gtgattgaga gtggaccaca ctgcgccaac acagaaatta 300

 ttgtaaagct ttctgatgga agagagctct gtctggaccc caaggaaaac 350

 tgggtgcaga gggttgtgga gaagtttttg aagagggctg agaattcata 400

 aaaaaattca ttctctgtgg tatccaagaa tcagtgaaga tgccagtgaa 450

 acttcaagca aatctacttc aacacttcat gtattgtgtg ggtctgttgt 500

 agggttgcca gatgcaatac aagattcctg gttaaatttg aatttcagta 550

 aacaatgaat agtttttcat tgtaccatga aatatccaga acatacttat 600

 atgtaaagta ttatttattt gaatctacaa aaaacaacaa ataattttta 650

 aatataagga ttttcctaga tattgcacgg gagaatatac aaatagcaaa 700

 attgaggcca agggccaaga gaatatccga actttaattt caggaattga 750

 atgggtttgc tagaatgtga tatttgaagc atcacataaa aatgatggga 800

 caataaattt tgccataaag tcaaatttag ctggaaatcc tggatttttt 850

 tctgttaaat ctggcaaccc tagtctgcta gccaggatcc acaagtcctt 900

 gttccactgt gccttggttt ctcctttatt tctaagtgga aaaagtatta 950

 gccaccatct tacctcacag tgatgttgtg aggacatgtg gaagcacttt 1000

 aagttttttc atcataacat aaattatttt caagtgtaac ttattaacct 1050

 atttattatt tatgtattta tttaagcatc aaatatttgt gcaagaattt 1100

 ggaaaaatag aagatgaatc attgattgaa tagttataaa gatgttatag 1150

 taaatttatt ttattttaga tattaaatga tgttttatta gataaatttc 1200

 aatcagggtt tttagattaa acaaacaaac aattgggtac ccagttaaat 1250

 tttcatttca gataaacaac aaataatttt ttagtataag tacattattg 1300

 tttatctgaa attttaattg aactaacaat cctagtttga tactcccagt 1350

 cttgtcattg ccagctgtgt tggtagtgct gtgttgaatt acggaataat 1400

 gagttagaac tattaaaaca gccaaaactc cacagtcaat attagtaatt 1450

 tcttgctggt tgaaacttgt ttattatgta caaatagatt cttataatat 1500

 tatttaaatg actgcatttt taaatacaag gctttatatt tttaacttta 1550

 agatgttttt atgtgctctc caaatttttt ttactgtttc tgattgtatg 1600

 gaaatataaa agtaaatatg aaacatttaa aatataattt gttgtcaaag 1650

 taaaaaaaaa aaaaaa 1666

<210> 5298
<211> 99
<212> PRT
<213> Homo sapien

<400> 5298
 Met Thr Ser Lys Leu Ala Val Ala Leu Leu Ala Ala Phe Leu Ile
   1               5                  10                  15

 Ser Ala Ala Leu Cys Glu Gly Ala Val Leu Pro Arg Ser Ala Lys
                  20                  25                  30

 Glu Leu Arg Cys Gln Cys Ile Lys Thr Tyr Ser Lys Pro Phe His
                  35                  40                  45

 Pro Lys Phe Ile Lys Glu Leu Arg Val Ile Glu Ser Gly Pro His
                  50                  55                  60

 Cys Ala Asn Thr Glu Ile Ile Val Lys Leu Ser Asp Gly Arg Glu
                  65                  70                  75

 Leu Cys Leu Asp Pro Lys Glu Asn Trp Val Gln Arg Val Val Glu
                  80                  85                  90

 Lys Phe Leu Lys Arg Ala Glu Asn Ser
                  95

<210> 5299
<211> 924
<212> DNA
<213> Homo sapien

<400> 5299
 cagagcccca cgaaggacca gaacaagaca gagtgcctcc tgccgatcca 50

 aacatgagcc gcctgcccgt cctgctcctg ctccaactcc tggtccgccc 100

 cggactccaa gctcccatga cccagacaac gcccttgaag acaagctggg 150

 ttaactgctc taacatgatc gatgaaatta taacacactt aaagcagcca 200

 cctttgcctt tgctggactt caacaacctc aatggggaag accaagacat 250

 tctgatggaa aataaccttc gaaggccaaa cctggaggca ttcaacaggg 300

 ctgtcaagag tttacagaac gcatcagcaa ttgagagcat tcttaaaaat 350

 ctcctgccat gtctgcccct ggccacggcc gcacccacgc gacatccaat 400

 ccatatcaag gacggtgact ggaatgaatt ccggaggaaa ctgacgttct 450

 atctgaaaac ccttgagaat gcgcaggctc aacagacgac tttgagcctc 500

 gcgatctttt gagtccaacg tccagctcgt tctctgggcc ttctcaccac 550

 agagcctcgg gacatcaaaa acagcagaac ttctgaaacc tctgggtcat 600

 ctctcacaca ttccaggacc agaagcattt caccttttcc tgcggcatca 650

 gatgaattgt taattatcta atttctgaaa tgtgcagctc ccatttggcc 700

 ttgtgcggtt gtgttctcat ttttatccca ttgagactat ttatttatgt 750

 atgtatgtat ttatttattt attgcctgga gtgtgaactg tatttatttt 800

 agcagaggag ccatgtcctg ctgcttctgc aaaaaactca gagtggggtg 850

 gggagcatgt tcatttgtac ctcgagtttt aaactggttc ctagggatgt 900

 gtgagaataa actagactct gaac 924

<210> 5300
<211> 152
<212> PRT
<213> Homo sapien

<400> 5300
 Met Ser Arg Leu Pro Val Leu Leu Leu Leu Gln Leu Leu Val Arg
   1               5                  10                  15

 Pro Gly Leu Gln Ala Pro Met Thr Gln Thr Thr Pro Leu Lys Thr
                  20                  25                  30

 Ser Trp Val Asn Cys Ser Asn Met Ile Asp Glu Ile Ile Thr His
                  35                  40                  45

 Leu Lys Gln Pro Pro Leu Pro Leu Leu Asp Phe Asn Asn Leu Asn
                  50                  55                  60

 Gly Glu Asp Gln Asp Ile Leu Met Glu Asn Asn Leu Arg Arg Pro
                  65                  70                  75

 Asn Leu Glu Ala Phe Asn Arg Ala Val Lys Ser Leu Gln Asn Ala
                  80                  85                  90

 Ser Ala Ile Glu Ser Ile Leu Lys Asn Leu Leu Pro Cys Leu Pro
                  95                 100                 105

 Leu Ala Thr Ala Ala Pro Thr Arg His Pro Ile His Ile Lys Asp
                 110                 115                 120

 Gly Asp Trp Asn Glu Phe Arg Arg Lys Leu Thr Phe Tyr Leu Lys
                 125                 130                 135

 Thr Leu Glu Asn Ala Gln Ala Gln Gln Thr Thr Leu Ser Leu Ala
                 140                 145                 150

 Ile Phe


<210> 5301
<211> 591
<212> DNA
<213> Homo sapien

<400> 5301
 ccgctgtcaa gatgcttctg gccatggtcc ttacctctgc cctgctcctg 50

 tgctccgtgg caggccaggg gtgtccaacc ttggcgggga tcctggacat 100

 caacttcctc atcaacaaga tgcaggaaga tccagcttcc aagtgccact 150

 gcagtgctaa tgtgaccagt tgtctctgtt tgggcattcc ctctgacaac 200

 tgcaccagac catgcttcag tgagagactg tctcagatga ccaataccac 250

 catgcaaaca agatacccac tgattttcag tcgggtgaaa aaatcagttg 300

 aagtactaaa gaacaacaag tgtccatatt tttcctgtga acagccatgc 350

 aaccaaacca cggcaggcaa cgcgctgaca tttctgaaga gtcttctgga 400

 aattttccag aaagaaaaga tgagagggat gagaggcaag atatgaagat 450

 gaaatattat ttatcctatt tattaaattt aaaaagcttt ctctttaagt 500

 tgctacaatt taaaaatcaa gtaagctact ctaaatcagt atcagttgtg 550

 attatttgtt taacattgta tgtctttatt ttgaaataaa t 591

<210> 5302
<211> 144
<212> PRT
<213> Homo sapien

<400> 5302
 Met Leu Leu Ala Met Val Leu Thr Ser Ala Leu Leu Leu Cys Ser
   1               5                  10                  15

 Val Ala Gly Gln Gly Cys Pro Thr Leu Ala Gly Ile Leu Asp Ile
                  20                  25                  30

 Asn Phe Leu Ile Asn Lys Met Gln Glu Asp Pro Ala Ser Lys Cys
                  35                  40                  45

 His Cys Ser Ala Asn Val Thr Ser Cys Leu Cys Leu Gly Ile Pro
                  50                  55                  60

 Ser Asp Asn Cys Thr Arg Pro Cys Phe Ser Glu Arg Leu Ser Gln
                  65                  70                  75

 Met Thr Asn Thr Thr Met Gln Thr Arg Tyr Pro Leu Ile Phe Ser
                  80                  85                  90

 Arg Val Lys Lys Ser Val Glu Val Leu Lys Asn Asn Lys Cys Pro
                  95                 100                 105

 Tyr Phe Ser Cys Glu Gln Pro Cys Asn Gln Thr Thr Ala Gly Asn
                 110                 115                 120

 Ala Leu Thr Phe Leu Lys Ser Leu Leu Glu Ile Phe Gln Lys Glu
                 125                 130                 135

 Lys Met Arg Gly Met Arg Gly Lys Ile
                 140

<210> 5303
<211> 2960
<212> DNA
<213> Homo sapien

<400> 5303
 ggcacgaggg tgtgcgtgat ggagaaaatt gggcaccagg gctgctcccg 50

 agattctcag atctgatttc cacgcttgct accaaaatag tctgggcagg 100

 ccacttttgg aagtaggcgt tatctagtga gcaggcggcc gctttcgatt 150

 tcgctttccc ctaaatggct gagcttctcg ccagcgcagg atcagcctgt 200

 tcctgggact ttccgagagc cccgccctcg ttccctcccc cagccgccag 250

 taggggagga ctcggcggta cccggagctt caggccccac cggggcgcgg 300

 agagtcccag gcccggccgg gaccgggacg gcgtccgagt gccaatggct 350

 agctctaggt gtcccgctcc ccgcgggtgc cgctgcctcc ccggagcttc 400

 tctcgcatgg ctggggacag tactgctact tctcgccgac tgggtgctgc 450

 tccggaccgc gctgccccgc atattctccc tgctggtgcc caccgcgctg 500

 ccactgctcc gggtctgggc ggtgggcctg agccgctggg ccgtgctctg 550

 gctgggggcc tgcggggtcc tcagggcaac ggttggctcc aagagcgaaa 600

 acgcaggtgc ccagggctgg ctggctgctt tgaagccatt agctgcggca 650

 ctgggcttgg ccctgccggg acttgccttg ttccgagagc tgatctcatg 700

 gggagccccc gggtccgcgg atagcaccag gctactgcac tggggaagtc 750

 accctaccgc cttcgttgtc agttatgcag cggcactgcc cgcagcagcc 800

 ctgtggcaca aactcgggag cctctgggtg cccggcggtc agggcggctc 850

 tggaaaccct gtgcgtcggc ttctaggctg cctgggctcg gagacgcgcc 900

 gcctctcgct gttcctggtc ctggtggtcc tctcctctct tggggagatg 950

 gccattccat tctttacggg ccgcctcact gactggattc tacaagatgg 1000

 ctcagccgat accttcactc gaaacttaac tctcatgtcc attctcacca 1050

 tagccagtgc agtgctggag ttcgtgggtg acgggatcta taacaacacc 1100

 atgggccacg tgcacagcca cttgcaggga gaggtgtttg gggctgtcct 1150

 gcgccaggag acggagtttt tccaacagaa ccagacaggt aacatcatgt 1200

 ctcgggtaac agaggacacg tccaccctga gtgattctct gagtgagaat 1250

 ctgagcttat ttctgtggta cctggtgcga ggcctatgtc tcttggggat 1300

 catgctctgg ggatcagtgt ccctcaccat ggtcaccctg atcaccctgc 1350

 ctctgctttt ccttctgccc aagaaggtgg gaaaatggta ccagttgctg 1400

 gaagtgcagg tgcgggaatc tctggcaaag tccagccagg tggccattga 1450

 ggctctgtcg gccatgccta cagttcgaag ctttgccaac gaggagggcg 1500

 aagcccagaa gtttagggaa aagctgcaag aaataaagac actcaaccag 1550

 aaggaggctg tggcctatgc agtcaactcc tggaccacta gtatttcagg 1600

 tatgctgctg aaagtgggaa tcctctacat tggtgggcag ctggtgacca 1650

 gtggggctgt aagcagtggg aaccttgtca catttgttct ctaccagatg 1700

 cagttcaccc aggctgtgga ggtactgctc tccatctacc ccagagtaca 1750

 gaaggctgtg ggctcctcag agaaaatatt tgagtacctg gaccgcaccc 1800

 ctcgctgccc acccagtggt ctgttgactc ccttacactt ggagggcctt 1850

 gtccagttcc aagatgtctc ctttgcctac ccaaaccgcc cagatgtctt 1900

 agtgctacag gggctgacat tcaccctacg ccctggcgag gtgacggcgc 1950

 tggtgggacc caatgggtct gggaagagca cagtggctgc cctgctgcag 2000

 aatctgtacc agcccaccgg gggacagctg ctgttggatg ggaagcccct 2050

 tccccaatat gagcaccgct acctgcacag gcaggtggct gcagtgggac 2100

 aagagccaca ggtatttgga agaagtcttc aagaaaatat tgcctatggc 2150

 ctgacccaga agccaactat ggaggaaatc acagctgctg cagtaaagtc 2200

 tggggcccat agtttcatct ctggactccc tcagggctat gacacagagg 2250

 tagacgaggc tgggagccag ctgtcagggg gtcagcgaca ggcagtggcg 2300

 ttggcccgag cattgatccg gaaaccgtgt gtacttatcc tggatgatgc 2350

 caccagtgcc ctggatgcaa acagccagtt acaggtggag cagctcctgt 2400

 acgaaagccc tgagcggtac tcccgctcag tgcttctcat cacccagcac 2450

 ctcagcctgg tggagcaggc tgaccacatc ctctttctgg aaggaggcgc 2500

 tatccgggag gggggaaccc accagcagct catggagaaa aaggggtgct 2550

 actgggccat ggtgcaggct cctgcagatg ctccagaatg aaagccttct 2600

 cagacctgcg cactccatct ccctcccttt tcttctctct gtggtggaga 2650

 accacagctg cagagtaggc agctgcctcc aggatgagtt acttgaaatt 2700

 tgccttgagt gtgttacctc ctttccaagc tcctcgtgat aatgcagact 2750

 tcctggagta caaacacagg atttgtaatt ccttactgta acggagttta 2800

 gagccagggc tgatgctttg gtgtggccag cactctgaaa ctgagaaatg 2850

 ttcagaatgt acggaaagat gatcagctat tttcaacata actgaaggca 2900

 tatgctggcc cataaacacc ctgtaggttc ttgatattta taataaaatt 2950

 ggtgttttgt 2960

<210> 5304
<211> 808
<212> PRT
<213> Homo sapien

<400> 5304
 Met Ala Glu Leu Leu Ala Ser Ala Gly Ser Ala Cys Ser Trp Asp
   1               5                  10                  15

 Phe Pro Arg Ala Pro Pro Ser Phe Pro Pro Pro Ala Ala Ser Arg
                  20                  25                  30

 Gly Gly Leu Gly Gly Thr Arg Ser Phe Arg Pro His Arg Gly Ala
                  35                  40                  45

 Glu Ser Pro Arg Pro Gly Arg Asp Arg Asp Gly Val Arg Val Pro
                  50                  55                  60

 Met Ala Ser Ser Arg Cys Pro Ala Pro Arg Gly Cys Arg Cys Leu
                  65                  70                  75

 Pro Gly Ala Ser Leu Ala Trp Leu Gly Thr Val Leu Leu Leu Leu
                  80                  85                  90

 Ala Asp Trp Val Leu Leu Arg Thr Ala Leu Pro Arg Ile Phe Ser
                  95                 100                 105

 Leu Leu Val Pro Thr Ala Leu Pro Leu Leu Arg Val Trp Ala Val
                 110                 115                 120

 Gly Leu Ser Arg Trp Ala Val Leu Trp Leu Gly Ala Cys Gly Val
                 125                 130                 135

 Leu Arg Ala Thr Val Gly Ser Lys Ser Glu Asn Ala Gly Ala Gln
                 140                 145                 150

 Gly Trp Leu Ala Ala Leu Lys Pro Leu Ala Ala Ala Leu Gly Leu
                 155                 160                 165

 Ala Leu Pro Gly Leu Ala Leu Phe Arg Glu Leu Ile Ser Trp Gly
                 170                 175                 180

 Ala Pro Gly Ser Ala Asp Ser Thr Arg Leu Leu His Trp Gly Ser
                 185                 190                 195

 His Pro Thr Ala Phe Val Val Ser Tyr Ala Ala Ala Leu Pro Ala
                 200                 205                 210

 Ala Ala Leu Trp His Lys Leu Gly Ser Leu Trp Val Pro Gly Gly
                 215                 220                 225

 Gln Gly Gly Ser Gly Asn Pro Val Arg Arg Leu Leu Gly Cys Leu
                 230                 235                 240

 Gly Ser Glu Thr Arg Arg Leu Ser Leu Phe Leu Val Leu Val Val
                 245                 250                 255

 Leu Ser Ser Leu Gly Glu Met Ala Ile Pro Phe Phe Thr Gly Arg
                 260                 265                 270

 Leu Thr Asp Trp Ile Leu Gln Asp Gly Ser Ala Asp Thr Phe Thr
                 275                 280                 285

 Arg Asn Leu Thr Leu Met Ser Ile Leu Thr Ile Ala Ser Ala Val
                 290                 295                 300

 Leu Glu Phe Val Gly Asp Gly Ile Tyr Asn Asn Thr Met Gly His
                 305                 310                 315

 Val His Ser His Leu Gln Gly Glu Val Phe Gly Ala Val Leu Arg
                 320                 325                 330

 Gln Glu Thr Glu Phe Phe Gln Gln Asn Gln Thr Gly Asn Ile Met
                 335                 340                 345

 Ser Arg Val Thr Glu Asp Thr Ser Thr Leu Ser Asp Ser Leu Ser
                 350                 355                 360

 Glu Asn Leu Ser Leu Phe Leu Trp Tyr Leu Val Arg Gly Leu Cys
                 365                 370                 375

 Leu Leu Gly Ile Met Leu Trp Gly Ser Val Ser Leu Thr Met Val
                 380                 385                 390

 Thr Leu Ile Thr Leu Pro Leu Leu Phe Leu Leu Pro Lys Lys Val
                 395                 400                 405

 Gly Lys Trp Tyr Gln Leu Leu Glu Val Gln Val Arg Glu Ser Leu
                 410                 415                 420

 Ala Lys Ser Ser Gln Val Ala Ile Glu Ala Leu Ser Ala Met Pro
                 425                 430                 435

 Thr Val Arg Ser Phe Ala Asn Glu Glu Gly Glu Ala Gln Lys Phe
                 440                 445                 450

 Arg Glu Lys Leu Gln Glu Ile Lys Thr Leu Asn Gln Lys Glu Ala
                 455                 460                 465

 Val Ala Tyr Ala Val Asn Ser Trp Thr Thr Ser Ile Ser Gly Met
                 470                 475                 480

 Leu Leu Lys Val Gly Ile Leu Tyr Ile Gly Gly Gln Leu Val Thr
                 485                 490                 495

 Ser Gly Ala Val Ser Ser Gly Asn Leu Val Thr Phe Val Leu Tyr
                 500                 505                 510

 Gln Met Gln Phe Thr Gln Ala Val Glu Val Leu Leu Ser Ile Tyr
                 515                 520                 525

 Pro Arg Val Gln Lys Ala Val Gly Ser Ser Glu Lys Ile Phe Glu
                 530                 535                 540

 Tyr Leu Asp Arg Thr Pro Arg Cys Pro Pro Ser Gly Leu Leu Thr
                 545                 550                 555

 Pro Leu His Leu Glu Gly Leu Val Gln Phe Gln Asp Val Ser Phe
                 560                 565                 570

 Ala Tyr Pro Asn Arg Pro Asp Val Leu Val Leu Gln Gly Leu Thr
                 575                 580                 585

 Phe Thr Leu Arg Pro Gly Glu Val Thr Ala Leu Val Gly Pro Asn
                 590                 595                 600

 Gly Ser Gly Lys Ser Thr Val Ala Ala Leu Leu Gln Asn Leu Tyr
                 605                 610                 615

 Gln Pro Thr Gly Gly Gln Leu Leu Leu Asp Gly Lys Pro Leu Pro
                 620                 625                 630

 Gln Tyr Glu His Arg Tyr Leu His Arg Gln Val Ala Ala Val Gly
                 635                 640                 645

 Gln Glu Pro Gln Val Phe Gly Arg Ser Leu Gln Glu Asn Ile Ala
                 650                 655                 660

 Tyr Gly Leu Thr Gln Lys Pro Thr Met Glu Glu Ile Thr Ala Ala
                 665                 670                 675

 Ala Val Lys Ser Gly Ala His Ser Phe Ile Ser Gly Leu Pro Gln
                 680                 685                 690

 Gly Tyr Asp Thr Glu Val Asp Glu Ala Gly Ser Gln Leu Ser Gly
                 695                 700                 705

 Gly Gln Arg Gln Ala Val Ala Leu Ala Arg Ala Leu Ile Arg Lys
                 710                 715                 720

 Pro Cys Val Leu Ile Leu Asp Asp Ala Thr Ser Ala Leu Asp Ala
                 725                 730                 735

 Asn Ser Gln Leu Gln Val Glu Gln Leu Leu Tyr Glu Ser Pro Glu
                 740                 745                 750

 Arg Tyr Ser Arg Ser Val Leu Leu Ile Thr Gln His Leu Ser Leu
                 755                 760                 765

 Val Glu Gln Ala Asp His Ile Leu Phe Leu Glu Gly Gly Ala Ile
                 770                 775                 780

 Arg Glu Gly Gly Thr His Gln Gln Leu Met Glu Lys Lys Gly Cys
                 785                 790                 795

 Tyr Trp Ala Met Val Gln Ala Pro Ala Asp Ala Pro Glu
                 800                 805

<210> 5305
<211> 1585
<212> DNA
<213> Homo sapien

<400> 5305
 cacaccctga caagctgcca ggcaggttct cttcctctca catactgacc 50

 cacggctcca ccctctctcc cctggaaagg acaccatgag cactgaaagc 100

 atgatccggg acgtggagct ggccgaggag gcgctcccca agaagacagg 150

 ggggccccag ggctccaggc ggtgcttgtt cctcagcctc ttctccttcc 200

 tgatcgtggc aggcgccacc acgctcttct gcctgctgca ctttggagtg 250

 atcggccccc agagggaaga gtcccccagg gacctctctc taatcagccc 300

 tctggcccag gcagtcagat catcttctcg aaccccgagt gacaagcctg 350

 tagcccatgt tgtagcaaac cctcaagctg aggggcagct ccagtggctg 400

 aaccgccggg ccaatgccct cctggccaat ggcgtggagc tgagagataa 450

 ccagctggtg gtgccatcag agggcctgta cctcatctac tcccaggtcc 500

 tcttcaaggg ccaaggctgc ccctccaccc atgtgctcct cacccacacc 550

 atcagccgca tcgccgtctc ctaccagacc aaggtcaacc tcctctctgc 600

 catcaagagc ccctgccaga gggagacccc agagggggct gaggccaagc 650

 cctggtatga gcccatctat ctgggagggg tcttccagct ggagaagggt 700

 gaccgactca gcgctgagat caatcggccc gactatctcg actttgccga 750

 gtctgggcag gtctactttg ggatcattgc cctgtgagga ggacgaacat 800

 ccaaccttcc caaacgcctc ccctgcccca atccctttat taccccctcc 850

 ttcagacacc ctcaacctct tctggctcaa aaagagaatt gggggcttag 900

 ggtcggaacc caagcttaga actttaagca acaagaccac cacttcgaaa 950

 cctgggattc aggaatgtgt ggcctgcaca gtgaagtgct ggcaaccact 1000

 aagaattcaa actggggcct ccagaactca ctggggccta cagctttgat 1050

 ccctgacatc tggaatctgg agaccaggga gcctttggtt ctggccagaa 1100

 tgctgcagga cttgagaaga cctcacctag aaattgacac aagtggacct 1150

 taggccttcc tctctccaga tgtttccaga cttccttgag acacggagcc 1200

 cagccctccc catggagcca gctccctcta tttatgtttg cacttgtgat 1250

 tatttattat ttatttatta tttatttatt tacagatgaa tgtatttatt 1300

 tgggagaccg gggtatcctg ggggacccaa tgtaggagct gccttggctc 1350

 agacatgttt tccgtgaaaa cggaggctga acaataggct gttcccatgt 1400

 agccccctgg cctctgtgcc ttcttttgat tatgtttttt aaaatattat 1450

 ctgattaagt tgtctaaaca atgctgattt ggtgaccaac tgtcactcat 1500

 tgctgaggcc tctgctcccc agggagttgt gtctgtaatc ggcctactat 1550

 tcagtggcga gaaataaagg ttgcttagga aagaa 1585

<210> 5306
<211> 233
<212> PRT
<213> Homo sapien

<400> 5306
 Met Ser Thr Glu Ser Met Ile Arg Asp Val Glu Leu Ala Glu Glu
   1               5                  10                  15

 Ala Leu Pro Lys Lys Thr Gly Gly Pro Gln Gly Ser Arg Arg Cys
                  20                  25                  30

 Leu Phe Leu Ser Leu Phe Ser Phe Leu Ile Val Ala Gly Ala Thr
                  35                  40                  45

 Thr Leu Phe Cys Leu Leu His Phe Gly Val Ile Gly Pro Gln Arg
                  50                  55                  60

 Glu Glu Ser Pro Arg Asp Leu Ser Leu Ile Ser Pro Leu Ala Gln
                  65                  70                  75

 Ala Val Arg Ser Ser Ser Arg Thr Pro Ser Asp Lys Pro Val Ala
                  80                  85                  90

 His Val Val Ala Asn Pro Gln Ala Glu Gly Gln Leu Gln Trp Leu
                  95                 100                 105

 Asn Arg Arg Ala Asn Ala Leu Leu Ala Asn Gly Val Glu Leu Arg
                 110                 115                 120

 Asp Asn Gln Leu Val Val Pro Ser Glu Gly Leu Tyr Leu Ile Tyr
                 125                 130                 135

 Ser Gln Val Leu Phe Lys Gly Gln Gly Cys Pro Ser Thr His Val
                 140                 145                 150

 Leu Leu Thr His Thr Ile Ser Arg Ile Ala Val Ser Tyr Gln Thr
                 155                 160                 165

 Lys Val Asn Leu Leu Ser Ala Ile Lys Ser Pro Cys Gln Arg Glu
                 170                 175                 180

 Thr Pro Glu Gly Ala Glu Ala Lys Pro Trp Tyr Glu Pro Ile Tyr
                 185                 190                 195

 Leu Gly Gly Val Phe Gln Leu Glu Lys Gly Asp Arg Leu Ser Ala
                 200                 205                 210

 Glu Ile Asn Arg Pro Asp Tyr Leu Asp Phe Ala Glu Ser Gly Gln
                 215                 220                 225

 Val Tyr Phe Gly Ile Ile Ala Leu
                 230

<210> 5307
<211> 1386
<212> DNA
<213> Homo sapien

<400> 5307
 gccccatctc cttgggctgc ccgtgcttcg tgctttggac taccgcccag 50

 cagtgtcctg ccctctgcct gggcctcggt ccctcctgca cctgctgcct 100

 ggatccccgg cctgcctggg cctgggcctt ggttctcccc atgacaccac 150

 ctgaacgtct cttcctccca agggtgtgtg gcaccaccct acacctcctc 200

 cttctggggc tgctgctggt tctgctgcct ggggcccagg ggctccctgg 250

 tgttggcctc acaccttcag ctgcccagac tgcccgtcag caccccaaga 300

 tgcatcttgc ccacagcacc ctcaaacctg ctgctcacct cattggagac 350

 cccagcaagc agaactcact gctctggaga gcaaacacgg accgtgcctt 400

 cctccaggat ggtttctcct tgagcaacaa ttctctcctg gtccccacca 450

 gtggcatcta cttcgtctac tcccaggtgg tcttctctgg gaaagcctac 500

 tctcccaagg ccacctcctc cccactctac ctggcccatg aggtccagct 550

 cttctcctcc cagtacccct tccatgtgcc tctcctcagc tcccagaaga 600

 tggtgtatcc agggctgcag gaaccctggc tgcactcgat gtaccacggg 650

 gctgcgttcc agctcaccca gggagaccag ctatccaccc acacagatgg 700

 catcccccac ctagtcctca gccctagtac tgtcttcttt ggagccttcg 750

 ctctgtagaa cttggaaaaa tccagaaaga aaaaataatt gatttcaaga 800

 ccttctcccc attctgcctc cattctgacc atttcagggg tcgtcaccac 850

 ctctcctttg gccattccaa cagctcaagt cttccctgat caagtcaccg 900

 gagctttcaa agaaggaatt ctaggcatcc caggggacca cacctccctg 950

 aaccatccct gatgtctgtc tggctgagga tttcaagcct gcctaggaat 1000

 tcccagccca aagctgttgg tctgtcccac cagctaggtg gggcctagat 1050

 ccacacacag aggaagagca ggcacatgga ggagcttggg ggatgactag 1100

 aggcagggag gggactattt atgaaggcaa aaaaattaaa ttatttattt 1150

 atggaggatg gagagagggg aataatagaa gaacatccaa ggagaaacag 1200

 agacaggccc aagagatgaa gagtgagagg gcatgcgcac aaggctgacc 1250

 aagagagaaa gaagtaggca tgagggatca cagggcccca gaaggcaggg 1300

 aaaggctctg aaagccagct gccgaccaga gccccacacg gaggcatctg 1350

 caccctcgat gaagcccaat aaacctcttt tctctg 1386

<210> 5308
<211> 205
<212> PRT
<213> Homo sapien

<400> 5308
 Met Thr Pro Pro Glu Arg Leu Phe Leu Pro Arg Val Cys Gly Thr
   1               5                  10                  15

 Thr Leu His Leu Leu Leu Leu Gly Leu Leu Leu Val Leu Leu Pro
                  20                  25                  30

 Gly Ala Gln Gly Leu Pro Gly Val Gly Leu Thr Pro Ser Ala Ala
                  35                  40                  45

 Gln Thr Ala Arg Gln His Pro Lys Met His Leu Ala His Ser Thr
                  50                  55                  60

 Leu Lys Pro Ala Ala His Leu Ile Gly Asp Pro Ser Lys Gln Asn
                  65                  70                  75

 Ser Leu Leu Trp Arg Ala Asn Thr Asp Arg Ala Phe Leu Gln Asp
                  80                  85                  90

 Gly Phe Ser Leu Ser Asn Asn Ser Leu Leu Val Pro Thr Ser Gly
                  95                 100                 105

 Ile Tyr Phe Val Tyr Ser Gln Val Val Phe Ser Gly Lys Ala Tyr
                 110                 115                 120

 Ser Pro Lys Ala Thr Ser Ser Pro Leu Tyr Leu Ala His Glu Val
                 125                 130                 135

 Gln Leu Phe Ser Ser Gln Tyr Pro Phe His Val Pro Leu Leu Ser
                 140                 145                 150

 Ser Gln Lys Met Val Tyr Pro Gly Leu Gln Glu Pro Trp Leu His
                 155                 160                 165

 Ser Met Tyr His Gly Ala Ala Phe Gln Leu Thr Gln Gly Asp Gln
                 170                 175                 180

 Leu Ser Thr His Thr Asp Gly Ile Pro His Leu Val Leu Ser Pro
                 185                 190                 195

 Ser Thr Val Phe Phe Gly Ala Phe Ala Leu
                 200                 205

<210> 5309
<211> 1794
<212> DNA
<213> Homo sapien

<400> 5309
 cccgcgccct ccgttcgctc cggacaccat ggacaagttt tggtggcacg 50

 cagcctgggg actctgcctc gtgccgctga gcctggcgca gatcgatttg 100

 aatataacct gccgctttgc aggtgtattc cacgtggaga aaaatggtcg 150

 ctacagcatc tctcggacgg aggccgctga cctctgcaag gctttcaata 200

 gcaccttgcc cacaatggcc cagatggaga aagctctgag catcggattt 250

 gagacctgca ggtatgggtt catagaaggg catgtggtga ttccccggat 300

 ccaccccaac tccatctgtg cagcaaacaa cacaggggtg tacatcctca 350

 catacaacac ctcccagtat gacacatatt gcttcaatgc ttcagctcca 400

 cctgaagaag attgtacatc agtcacagac ctgcccaatg cctttgatgg 450

 accaattacc ataactattg ttaaccgtga tggcacccgc tatgtccaga 500

 aaggagaata cagaacgaat cctgaagaca tctaccccag caaccctact 550

 gatgatgacg tgagcagcgg ctcctccagt gaaaggagca gcacttcagg 600

 aggttacatc ttttacacct tttctactgt acaccccatc ccagacgaag 650

 acagtccctg gatcaccgac agcacagaca gaatccctgc taccagagac 700

 caagacacat tccaccccag tggggggtcc cataccactc atggatctga 750

 atcagatgga cactcacatg ggagtcaaga aggtggagca aacacaacct 800

 ctggtcctat aaggacaccc caaattccag aatggctgat catcttggca 850

 tccctcttgg ccttggcttt gattcttgca gtttgcattg cagtcaacag 900

 tcgaagaagg tgtgggcaga agaaaaagct agtgatcaac agtggcaatg 950

 gagctgtgga ggacagaaag ccaagtggac tcaacggaga ggccagcaag 1000

 tctcaggaaa tggtgcattt ggtgaacaag gagtcgtcag aaactccaga 1050

 ccagtttatg acagctgatg agacaaggaa cctgcagaat gtggacatga 1100

 agattggggt gtaacaccta caccattatc ttggaaagaa acaaccgttg 1150

 gaaacataac cattacaggg agctgggaca cttaacagat gcaatgtgct 1200

 actgattgtt tcattgcgaa tcttttttag cataaaattt tctactcttt 1250

 ttgttttttg tgttttgttc tttaaagtca ggtccaattt gtaaaaacag 1300

 cattgctttg taaattaggg cccaattaat aatcagcaag aatttgatcg 1350

 ttcagttcca cttggaggcc ttcatcctcg ggtgtgctat ggatggcttc 1400

 taacaaaaac tacacatatg tattcctgat cgccaacctt tcccccacca 1450

 gctaaggaca tttcccaggg ttaatagggc ctggtccctg ggaggaaatt 1500

 tgaatgggtc cattttgccc ttccatagcc taatccctgg gcattgcttt 1550

 ccactgaggt tggggtgtac tagttacaca tcttcaacag accccctcta 1600

 gaaatttttc agatgcttct gggagacacc aaagggtgaa gctatttatc 1650

 tgtagtaaac tatttatctg tgtttttgaa atattaaacc ctggatcagt 1700

 cctttgatca gtataatttt ttaaagttac tttgtcagag gcacaaaagg 1750

 gtttaaactg attcataata aatatctgta cttcttcgat cttc 1794

<210> 5310
<211> 361
<212> PRT
<213> Homo sapien

<400> 5310
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val
   1               5                  10                  15

 Pro Leu Ser Leu Ala Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe
                  20                  25                  30

 Ala Gly Val Phe His Val Glu Lys Asn Gly Arg Tyr Ser Ile Ser
                  35                  40                  45

 Arg Thr Glu Ala Ala Asp Leu Cys Lys Ala Phe Asn Ser Thr Leu
                  50                  55                  60

 Pro Thr Met Ala Gln Met Glu Lys Ala Leu Ser Ile Gly Phe Glu
                  65                  70                  75

 Thr Cys Arg Tyr Gly Phe Ile Glu Gly His Val Val Ile Pro Arg
                  80                  85                  90

 Ile His Pro Asn Ser Ile Cys Ala Ala Asn Asn Thr Gly Val Tyr
                  95                 100                 105

 Ile Leu Thr Tyr Asn Thr Ser Gln Tyr Asp Thr Tyr Cys Phe Asn
                 110                 115                 120

 Ala Ser Ala Pro Pro Glu Glu Asp Cys Thr Ser Val Thr Asp Leu
                 125                 130                 135

 Pro Asn Ala Phe Asp Gly Pro Ile Thr Ile Thr Ile Val Asn Arg
                 140                 145                 150

 Asp Gly Thr Arg Tyr Val Gln Lys Gly Glu Tyr Arg Thr Asn Pro
                 155                 160                 165

 Glu Asp Ile Tyr Pro Ser Asn Pro Thr Asp Asp Asp Val Ser Ser
                 170                 175                 180

 Gly Ser Ser Ser Glu Arg Ser Ser Thr Ser Gly Gly Tyr Ile Phe
                 185                 190                 195

 Tyr Thr Phe Ser Thr Val His Pro Ile Pro Asp Glu Asp Ser Pro
                 200                 205                 210

 Trp Ile Thr Asp Ser Thr Asp Arg Ile Pro Ala Thr Arg Asp Gln
                 215                 220                 225

 Asp Thr Phe His Pro Ser Gly Gly Ser His Thr Thr His Gly Ser
                 230                 235                 240

 Glu Ser Asp Gly His Ser His Gly Ser Gln Glu Gly Gly Ala Asn
                 245                 250                 255

 Thr Thr Ser Gly Pro Ile Arg Thr Pro Gln Ile Pro Glu Trp Leu
                 260                 265                 270

 Ile Ile Leu Ala Ser Leu Leu Ala Leu Ala Leu Ile Leu Ala Val
                 275                 280                 285

 Cys Ile Ala Val Asn Ser Arg Arg Arg Cys Gly Gln Lys Lys Lys
                 290                 295                 300

 Leu Val Ile Asn Ser Gly Asn Gly Ala Val Glu Asp Arg Lys Pro
                 305                 310                 315

 Ser Gly Leu Asn Gly Glu Ala Ser Lys Ser Gln Glu Met Val His
                 320                 325                 330

 Leu Val Asn Lys Glu Ser Ser Glu Thr Pro Asp Gln Phe Met Thr
                 335                 340                 345

 Ala Asp Glu Thr Arg Asn Leu Gln Asn Val Asp Met Lys Ile Gly
                 350                 355                 360

 Val


<210> 5311
<211> 3084
<212> DNA
<213> Homo sapien

<400> 5311
 ctgggctcct ggttgcagag ctccaagtcc tcacacagat acgcctgttt 50

 gagaagcagc gggcaagaaa gacgcaagcc cagaggccct gccatttctg 100

 tgggctcagg tccctactgg ctcaggcccc tgcctccctc ggcaaggcca 150

 caatgaaccg gggagtccct tttaggcact tgcttctggt gctgcaactg 200

 gcgctcctcc cagcagccac tcagggaaag aaagtggtgc tgggcaaaaa 250

 aggggataca gtggaactga cctgtacagc ttcccagaag aagagcatac 300

 aattccactg gaaaaactcc aaccagataa agattctggg aaatcagggc 350

 tccttcttaa ctaaaggtcc atccaagctg aatgatcgcg ctgactcaag 400

 aagaagcctt tgggaccaag gaaactttcc cctgatcatc aagaatctta 450

 agatagaaga ctcagatact tacatctgtg aagtggagga ccagaaggag 500

 gaggtgcaat tgctagtgtt cggattgact gccaactctg acacccacct 550

 gcttcagggg cagagcctga ccctgacctt ggagagcccc cctggtagta 600

 gcccctcagt gcaatgtagg agtccaaggg gtaaaaacat acaggggggg 650

 aagaccctct ccgtgtctca gctggagctc caggatagtg gcacctggac 700

 atgcactgtc ttgcagaacc agaagaaggt ggagttcaaa atagacatcg 750

 tggtgctagc tttccagaag gcctccagca tagtctataa gaaagagggg 800

 gaacaggtgg agttctcctt cccactcgcc tttacagttg aaaagctgac 850

 gggcagtggc gagctgtggt ggcaggcgga gagggcttcc tcctccaagt 900

 cttggatcac ctttgacctg aagaacaagg aagtgtctgt aaaacgggtt 950

 acccaggacc ctaagctcca gatgggcaag aagctcccgc tccacctcac 1000

 cctgccccag gccttgcctc agtatgctgg ctctggaaac ctcaccctgg 1050

 cccttgaagc gaaaacagga aagttgcatc aggaagtgaa cctggtggtg 1100

 atgagagcca ctcagctcca gaaaaatttg acctgtgagg tgtggggacc 1150

 cacctcccct aagctgatgc tgagcttgaa actggagaac aaggaggcaa 1200

 aggtctcgaa gcgggagaag gcggtgtggg tgctgaaccc tgaggcgggg 1250

 atgtggcagt gtctgctgag tgactcggga caggtcctgc tggaatccaa 1300

 catcaaggtt ctgcccacat ggtccacccc ggtgcagcca atggccctga 1350

 ttgtgctggg gggcgtcgcc ggcctcctgc ttttcattgg gctaggcatc 1400

 ttcttctgtg tcaggtgccg gcaccgaagg cgccaagcag agcggatgtc 1450

 tcagatcaag agactcctca gtgagaagaa gacctgccag tgccctcacc 1500

 ggtttcagaa gacatgtagc cccatttgag gcacgaggcc aggcagatcc 1550

 cacttgcagc ctccccaggt gtctgccccg cgtttcctgc ctgcggacca 1600

 gatgaatgta gcagatccca ggcctctggc ctcctgttcg cctcctctac 1650

 aatttgccat tgtttctcct gggttaggcc ccggcttcac tggttgagtg 1700

 ttgctctcta gtttccagag gcttaatcac accgtcctcc acgccatttc 1750

 cttttccttc aagcctagcc cttctctcat tatttctctc tgaccctctc 1800

 cccactgctc atttggatcc caggggagtg ttcagggcca gccctggctg 1850

 gcatggaggg tgaggctggg tgtctggaag catggagcat gggactgttc 1900

 ttttacaaga caggaccctg ggaccacaga gggcaggagc ttgcacgaaa 1950

 tcacacagcc aagccagtca aggatggatg cagatccaga ggtttctggc 2000

 agccagtacc tcctgcccca tgctgcccgc ttctcaccct atgtgggtgg 2050

 ggccacagac tcacatcctg accttgcaca aacagcccct ctggacacag 2100

 ccccatgtac acggcctcaa gggatgtctc acatcctctg tctatttgag 2150

 acttagaaaa atcctacaag gctggcagtg acagaactaa gatgatcatc 2200

 tccagtttat agaccagaac cagagctcag agaggctaga tgattgatta 2250

 ccaagtgccg gactagcaag tgctggagtc gggactaacc caggtccctt 2300

 gtcccaagtt ccactgctgc ctcttgaatg cagggacaaa tgccacacgg 2350

 ctctcaccag tggctagtgg tgggtactca atgtgtactt ttgggttcac 2400

 agaagcacag cacccatggg aagggtccat ctcagagaat ttacgagcag 2450

 ggatgaaggc ctccctgtct aaaatccctc cttcatcccc cgctggtggc 2500

 agaatctgtt accagaggac aaagcctttg gctcttctaa tcagagtgca 2550

 agctgggagc acaggcactg caggagagaa tgcccagtga ccagtcactg 2600

 accctgtgca gaacctcctg gaagcgagct ttgctgggag agggggtagc 2650

 tagcctgaga gggaaccctc caagggacct caaaggtgat tgtgccaggc 2700

 tctgcgcctg ccccacaccc tcccttaccc tcctccagac cattcaggac 2750

 acagggaaat cagggttaca aatcttcttg atccacttct ctcaggatcc 2800

 cctctcttcc tacccttcct caccacttcc ctcagtccca actccttttc 2850

 cctatttcct tctcctcctg tctttaaagc ctgcctcttc caggaagacc 2900

 cccctattgc tgctggggct ccccatttgc ttactttgca tttgtgccca 2950

 ctctccaccc ctgctcccct gagctgaaat aaaaatacaa taaacttact 3000

 ataaagataa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3050

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 3084

<210> 5312
<211> 458
<212> PRT
<213> Homo sapien

<400> 5312
 Met Asn Arg Gly Val Pro Phe Arg His Leu Leu Leu Val Leu Gln
   1               5                  10                  15

 Leu Ala Leu Leu Pro Ala Ala Thr Gln Gly Lys Lys Val Val Leu
                  20                  25                  30

 Gly Lys Lys Gly Asp Thr Val Glu Leu Thr Cys Thr Ala Ser Gln
                  35                  40                  45

 Lys Lys Ser Ile Gln Phe His Trp Lys Asn Ser Asn Gln Ile Lys
                  50                  55                  60

 Ile Leu Gly Asn Gln Gly Ser Phe Leu Thr Lys Gly Pro Ser Lys
                  65                  70                  75

 Leu Asn Asp Arg Ala Asp Ser Arg Arg Ser Leu Trp Asp Gln Gly
                  80                  85                  90

 Asn Phe Pro Leu Ile Ile Lys Asn Leu Lys Ile Glu Asp Ser Asp
                  95                 100                 105

 Thr Tyr Ile Cys Glu Val Glu Asp Gln Lys Glu Glu Val Gln Leu
                 110                 115                 120

 Leu Val Phe Gly Leu Thr Ala Asn Ser Asp Thr His Leu Leu Gln
                 125                 130                 135

 Gly Gln Ser Leu Thr Leu Thr Leu Glu Ser Pro Pro Gly Ser Ser
                 140                 145                 150

 Pro Ser Val Gln Cys Arg Ser Pro Arg Gly Lys Asn Ile Gln Gly
                 155                 160                 165

 Gly Lys Thr Leu Ser Val Ser Gln Leu Glu Leu Gln Asp Ser Gly
                 170                 175                 180

 Thr Trp Thr Cys Thr Val Leu Gln Asn Gln Lys Lys Val Glu Phe
                 185                 190                 195

 Lys Ile Asp Ile Val Val Leu Ala Phe Gln Lys Ala Ser Ser Ile
                 200                 205                 210

 Val Tyr Lys Lys Glu Gly Glu Gln Val Glu Phe Ser Phe Pro Leu
                 215                 220                 225

 Ala Phe Thr Val Glu Lys Leu Thr Gly Ser Gly Glu Leu Trp Trp
                 230                 235                 240

 Gln Ala Glu Arg Ala Ser Ser Ser Lys Ser Trp Ile Thr Phe Asp
                 245                 250                 255

 Leu Lys Asn Lys Glu Val Ser Val Lys Arg Val Thr Gln Asp Pro
                 260                 265                 270

 Lys Leu Gln Met Gly Lys Lys Leu Pro Leu His Leu Thr Leu Pro
                 275                 280                 285

 Gln Ala Leu Pro Gln Tyr Ala Gly Ser Gly Asn Leu Thr Leu Ala
                 290                 295                 300

 Leu Glu Ala Lys Thr Gly Lys Leu His Gln Glu Val Asn Leu Val
                 305                 310                 315

 Val Met Arg Ala Thr Gln Leu Gln Lys Asn Leu Thr Cys Glu Val
                 320                 325                 330

 Trp Gly Pro Thr Ser Pro Lys Leu Met Leu Ser Leu Lys Leu Glu
                 335                 340                 345

 Asn Lys Glu Ala Lys Val Ser Lys Arg Glu Lys Ala Val Trp Val
                 350                 355                 360

 Leu Asn Pro Glu Ala Gly Met Trp Gln Cys Leu Leu Ser Asp Ser
                 365                 370                 375

 Gly Gln Val Leu Leu Glu Ser Asn Ile Lys Val Leu Pro Thr Trp
                 380                 385                 390

 Ser Thr Pro Val Gln Pro Met Ala Leu Ile Val Leu Gly Gly Val
                 395                 400                 405

 Ala Gly Leu Leu Leu Phe Ile Gly Leu Gly Ile Phe Phe Cys Val
                 410                 415                 420

 Arg Cys Arg His Arg Arg Arg Gln Ala Glu Arg Met Ser Gln Ile
                 425                 430                 435

 Lys Arg Leu Leu Ser Glu Lys Lys Thr Cys Gln Cys Pro His Arg
                 440                 445                 450

 Phe Gln Lys Thr Cys Ser Pro Ile
                 455

<210> 5313
<211> 1193
<212> DNA
<213> Homo sapien

<400> 5313
 tgaagatcag ctattagaag agaaagatca gttaagtcct ttggacctga 50

 tcagcttgat acaagaacta ctgatttcaa cttctttggc ttaattctct 100

 cggaaacgat gaaatataca agttatatct tggcttttca gctctgcatc 150

 gttttgggtt ctcttggctg ttactgccag gacccatatg taaaagaagc 200

 agaaaacctt aagaaatatt ttaatgcagg tcattcagat gtagcggata 250

 atggaactct tttcttaggc attttgaaga attggaaaga ggagagtgac 300

 agaaaaataa tgcagagcca aattgtctcc ttttacttca aactttttaa 350

 aaactttaaa gatgaccaga gcatccaaaa gagtgtggag accatcaagg 400

 aagacatgaa tgtcaagttt ttcaatagca acaaaaagaa acgagatgac 450

 ttcgaaaagc tgactaatta ttcggtaact gacttgaatg tccaacgcaa 500

 agcaatacat gaactcatcc aagtgatggc tgaactgtcg ccagcagcta 550

 aaacagggaa gcgaaaaagg agtcagatgc tgtttcaagg tcgaagagca 600

 tcccagtaat ggttgtcctg cctgcaatat ttgaatttta aatctaaatc 650

 tatttattaa tatttaacat tatttatatg gggaatatat ttttagactc 700

 atcaatcaaa taagtattta taatagcaac ttttgtgtaa tgaaaatgaa 750

 tatctattaa tatatgtatt atttataatt cctatatcct gtgactgtct 800

 cacttaatcc tttgttttct gactaattag gcaaggctat gtgattacaa 850

 ggctttatct caggggccaa ctaggcagcc aacctaagca agatcccatg 900

 ggttgtgtgt ttatttcact tgatgataca atgaacactt ataagtgaag 950

 tgatactatc cagttactgc cggtttgaaa atatgcctgc aatctgagcc 1000

 agtgctttaa tggcatgtca gacagaactt gaatgtgtca ggtgaccctg 1050

 atgaaaacat agcatctcag gagatttcat gcctggtgct tccaaatatt 1100

 gttgacaact gtgactgtac ccaaatggaa agtaactcat ttgttaaaat 1150

 tatcaatatc taatatatat gaataaagtg taagttcaca act 1193

<210> 5314
<211> 166
<212> PRT
<213> Homo sapien

<400> 5314
 Met Lys Tyr Thr Ser Tyr Ile Leu Ala Phe Gln Leu Cys Ile Val
   1               5                  10                  15

 Leu Gly Ser Leu Gly Cys Tyr Cys Gln Asp Pro Tyr Val Lys Glu
                  20                  25                  30

 Ala Glu Asn Leu Lys Lys Tyr Phe Asn Ala Gly His Ser Asp Val
                  35                  40                  45

 Ala Asp Asn Gly Thr Leu Phe Leu Gly Ile Leu Lys Asn Trp Lys
                  50                  55                  60

 Glu Glu Ser Asp Arg Lys Ile Met Gln Ser Gln Ile Val Ser Phe
                  65                  70                  75

 Tyr Phe Lys Leu Phe Lys Asn Phe Lys Asp Asp Gln Ser Ile Gln
                  80                  85                  90

 Lys Ser Val Glu Thr Ile Lys Glu Asp Met Asn Val Lys Phe Phe
                  95                 100                 105

 Asn Ser Asn Lys Lys Lys Arg Asp Asp Phe Glu Lys Leu Thr Asn
                 110                 115                 120

 Tyr Ser Val Thr Asp Leu Asn Val Gln Arg Lys Ala Ile His Glu
                 125                 130                 135

 Leu Ile Gln Val Met Ala Glu Leu Ser Pro Ala Ala Lys Thr Gly
                 140                 145                 150

 Lys Arg Lys Arg Ser Gln Met Leu Phe Gln Gly Arg Arg Ala Ser
                 155                 160                 165

 Gln


<210> 5315
<211> 1026
<212> DNA
<213> Homo sapien

<400> 5315
 cagcatgttg agccgggcag tgtgcggcac cagcaggcag ctgcctccgg 50

 ttttggggta tctgggctcc aggcagaagc acagcctccc cgacctgccc 100

 tacgactacg gcgccctgga acctcacatc aacgcgcaga tcatgcagct 150

 gcaccacagc aagcaccacg cggcctacgt gaacaacctg aacgtcaccg 200

 aggagaagta ccaggaggcg ttggccaagg gagatgttac agcccagata 250

 gctcttcagc ctgcactgaa gttcaatggt ggtggtcata tcaatcatag 300

 cattttctgg acaaacctca gccctaacgg tggtggagaa cccaaagggg 350

 agttgctgga agccatcaaa ctggactttg gttcctttga caagtttaag 400

 gagaagctga cggctgcatc tgttggtgtc caaggctcag gttggggttg 450

 gcttggtttc aataaggaac ggggacactt acaaattgct gcttgtccaa 500

 atcaggatcc actgcaagga acaacaggcc ttattccact gctggggatt 550

 gatgtgtggg agcacgctta ctaccttcag tataaaaatg tcaggcctga 600

 ttatctaaaa gctatttgga atgtaatcaa ctgggagaat gtaactgaaa 650

 gatacatggc ttgcaaaaag taaaccacga tcgttatgct gagtatgtta 700

 agctctttat gactgttttt gtagtggtat agagtactgc agaatacagt 750

 aagctgctct attgtagcat ttcttgatgt tgcttagtca cttatttcat 800

 aaacaactta atgttctgaa taatttctta ctaaacattt tgttattggg 850

 caagtgattg aaaatagtaa atgctttgtg tgattgaatc tgattggaca 900

 ttttcttcag agagctaaat tacaattgtc atttataaaa ccatcaaaaa 950

 tattccatcc atatactttg gggacttgta gggatgcctt tctagtccta 1000

 ttctattgca gttatagaaa atctag 1026

<210> 5316
<211> 222
<212> PRT
<213> Homo sapien

<400> 5316
 Met Leu Ser Arg Ala Val Cys Gly Thr Ser Arg Gln Leu Pro Pro
   1               5                  10                  15

 Val Leu Gly Tyr Leu Gly Ser Arg Gln Lys His Ser Leu Pro Asp
                  20                  25                  30

 Leu Pro Tyr Asp Tyr Gly Ala Leu Glu Pro His Ile Asn Ala Gln
                  35                  40                  45

 Ile Met Gln Leu His His Ser Lys His His Ala Ala Tyr Val Asn
                  50                  55                  60

 Asn Leu Asn Val Thr Glu Glu Lys Tyr Gln Glu Ala Leu Ala Lys
                  65                  70                  75

 Gly Asp Val Thr Ala Gln Ile Ala Leu Gln Pro Ala Leu Lys Phe
                  80                  85                  90

 Asn Gly Gly Gly His Ile Asn His Ser Ile Phe Trp Thr Asn Leu
                  95                 100                 105

 Ser Pro Asn Gly Gly Gly Glu Pro Lys Gly Glu Leu Leu Glu Ala
                 110                 115                 120

 Ile Lys Leu Asp Phe Gly Ser Phe Asp Lys Phe Lys Glu Lys Leu
                 125                 130                 135

 Thr Ala Ala Ser Val Gly Val Gln Gly Ser Gly Trp Gly Trp Leu
                 140                 145                 150

 Gly Phe Asn Lys Glu Arg Gly His Leu Gln Ile Ala Ala Cys Pro
                 155                 160                 165

 Asn Gln Asp Pro Leu Gln Gly Thr Thr Gly Leu Ile Pro Leu Leu
                 170                 175                 180

 Gly Ile Asp Val Trp Glu His Ala Tyr Tyr Leu Gln Tyr Lys Asn
                 185                 190                 195

 Val Arg Pro Asp Tyr Leu Lys Ala Ile Trp Asn Val Ile Asn Trp
                 200                 205                 210

 Glu Asn Val Thr Glu Arg Tyr Met Ala Cys Lys Lys
                 215                 220

<210> 5317
<211> 1909
<212> DNA
<213> Homo sapien

<400> 5317
 gaggtgtttc ccttagctat ggaaactcta taagagagat ccagcttgcc 50

 tcctcttgag cagtcagcaa cagggtcccg tccttgacac ctcagcctct 100

 acaggactga gaagaagtaa aaccgtttgc tggggctggc ctgactcacc 150

 agctgccatg cagcagccct tcaattaccc atatccccag atctactggg 200

 tggacagcag tgccagctct ccctgggccc ctccaggcac agttcttccc 250

 tgtccaacct ctgtgcccag aaggcctggt caaaggaggc caccaccacc 300

 accgccaccg ccaccactac cacctccgcc gccgccgcca ccactgcctc 350

 cactaccgct gccacccctg aagaagagag ggaaccacag cacaggcctg 400

 tgtctccttg tgatgttttt catggttctg gttgccttgg taggattggg 450

 cctggggatg tttcagctct tccacctaca gaaggagctg gcagaactcc 500

 gagagtctac cagccagatg cacacagcat catctttgga gaagcaaata 550

 ggccacccca gtccaccccc tgaaaaaaag gagctgagga aagtggccca 600

 tttaacaggc aagtccaact caaggtccat gcctctggaa tgggaagaca 650

 cctatggaat tgtcctgctt tctggagtga agtataagaa gggtggcctt 700

 gtgatcaatg aaactgggct gtactttgta tattccaaag tatacttccg 750

 gggtcaatct tgcaacaacc tgcccctgag ccacaaggtc tacatgagga 800

 actctaagta tccccaggat ctggtgatga tggaggggaa gatgatgagc 850

 tactgcacta ctgggcagat gtgggcccgc agcagctacc tgggggcagt 900

 gttcaatctt accagtgctg atcatttata tgtcaacgta tctgagctct 950

 ctctggtcaa ttttgaggaa tctcagacgt ttttcggctt atataagctc 1000

 taagagaagc actttgggat tctttccatt atgattcttt gttacaggca 1050

 ccgagaatgt tgtattcagt gagggtcttc ttacatgcat ttgaggtcaa 1100

 gtaagaagac atgaaccaag tggaccttga gaccacaggg ttcaaaatgt 1150

 ctgtagctcc tcaactcacc taatgtttat gagccagaca aatggaggaa 1200

 tatgacggaa gaacatagaa ctctgggctg ccatgtgaag agggagaagc 1250

 atgaaaaagc agctaccagg tgttctacac tcatcttagt gcctgagagt 1300

 atttaggcag attgaaaagg acacctttta actcacctct caaggtgggc 1350

 cttgctacct caagggggac tgtctttcag atacatggtt gtgacctgag 1400

 gatttaaggg atggaaaagg aagactagag gcttgcataa taagctaaag 1450

 aggctgaaag aggccaatgc cccactggca gcatcttcac ttctaaatgc 1500

 atatcctgag ccatcggtga aactaacaga taagcaagag agatgttttg 1550

 gggactcatt tcattcctaa cacagcatgt gtatttccag tgcaattgta 1600

 ggggtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtatgac taaagagaga 1650

 atgtagatat tgtgaagtac atattaggaa aatatgggtt gcatttggtc 1700

 aagattttga atgcttcctg acaatcaact ctaatagtgc ttaaaaatca 1750

 ttgattgtca gctactaatg atgttttcct ataatataat aaatatttat 1800

 gtagatgtgc atttttgtga aatgaaaaca tgtaataaaa agtatatgtt 1850

 aggatacaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1900

 aaaaaaaaa 1909

<210> 5318
<211> 281
<212> PRT
<213> Homo sapien

<400> 5318
 Met Gln Gln Pro Phe Asn Tyr Pro Tyr Pro Gln Ile Tyr Trp Val
   1               5                  10                  15

 Asp Ser Ser Ala Ser Ser Pro Trp Ala Pro Pro Gly Thr Val Leu
                  20                  25                  30

 Pro Cys Pro Thr Ser Val Pro Arg Arg Pro Gly Gln Arg Arg Pro
                  35                  40                  45

 Pro Pro Pro Pro Pro Pro Pro Pro Leu Pro Pro Pro Pro Pro Pro
                  50                  55                  60

 Pro Pro Leu Pro Pro Leu Pro Leu Pro Pro Leu Lys Lys Arg Gly
                  65                  70                  75

 Asn His Ser Thr Gly Leu Cys Leu Leu Val Met Phe Phe Met Val
                  80                  85                  90

 Leu Val Ala Leu Val Gly Leu Gly Leu Gly Met Phe Gln Leu Phe
                  95                 100                 105

 His Leu Gln Lys Glu Leu Ala Glu Leu Arg Glu Ser Thr Ser Gln
                 110                 115                 120

 Met His Thr Ala Ser Ser Leu Glu Lys Gln Ile Gly His Pro Ser
                 125                 130                 135

 Pro Pro Pro Glu Lys Lys Glu Leu Arg Lys Val Ala His Leu Thr
                 140                 145                 150

 Gly Lys Ser Asn Ser Arg Ser Met Pro Leu Glu Trp Glu Asp Thr
                 155                 160                 165

 Tyr Gly Ile Val Leu Leu Ser Gly Val Lys Tyr Lys Lys Gly Gly
                 170                 175                 180

 Leu Val Ile Asn Glu Thr Gly Leu Tyr Phe Val Tyr Ser Lys Val
                 185                 190                 195

 Tyr Phe Arg Gly Gln Ser Cys Asn Asn Leu Pro Leu Ser His Lys
                 200                 205                 210

 Val Tyr Met Arg Asn Ser Lys Tyr Pro Gln Asp Leu Val Met Met
                 215                 220                 225

 Glu Gly Lys Met Met Ser Tyr Cys Thr Thr Gly Gln Met Trp Ala
                 230                 235                 240

 Arg Ser Ser Tyr Leu Gly Ala Val Phe Asn Leu Thr Ser Ala Asp
                 245                 250                 255

 His Leu Tyr Val Asn Val Ser Glu Leu Ser Leu Val Asn Phe Glu
                 260                 265                 270

 Glu Ser Gln Thr Phe Phe Gly Leu Tyr Lys Leu
                 275                 280

<210> 5319
<211> 2273
<212> DNA
<213> Homo sapien

<400> 5319
 caggactgcc tgagacaagc cacaagctga acagagaaag tggattgaac 50

 aaggacgcat ttccccagta catccacaac atgctgtcca catctcgttc 100

 tcggtttatc agaaatacca acgagagcgg tgaagaagtc accacctttt 150

 ttgattatga ttacggtgct ccctgtcata aatttgacgt gaagcaaatt 200

 ggggcccaac tcctgcctcc gctctactcg ctggtgttca tctttggttt 250

 tgtgggcaac atgctggtcg tcctcatctt aataaactgc aaaaagctga 300

 agtgcttgac tgacatttac ctgctcaacc tggccatctc tgatctgctt 350

 tttcttatta ctctcccatt gtgggctcac tctgctgcaa atgagtgggt 400

 ctttgggaat gcaatgtgca aattattcac agggctgtat cacatcggtt 450

 attttggcgg aatcttcttc atcatcctcc tgacaatcga tagatacctg 500

 gctattgtcc atgctgtgtt tgctttaaaa gccaggacgg tcacctttgg 550

 ggtggtgaca agtgtgatca cctggttggt ggctgtgttt gcttctgtcc 600

 caggaatcat ctttactaaa tgccagaaag aagattctgt ttatgtctgt 650

 ggcccttatt ttccacgagg atggaataat ttccacacaa taatgaggaa 700

 cattttgggg ctggtcctgc cgctgctcat catggtcatc tgctactcgg 750

 gaatcctgaa aaccctgctt cggtgtcgaa acgagaagaa gaggcatagg 800

 gcagtgagag tcatcttcac catcatgatt gtttactttc tcttctggac 850

 tccctataac attgtcattc tcctgaacac cttccaggaa ttcttcggcc 900

 tgagtaactg tgaaagcacc agtcaactgg accaagccac gcaggtgaca 950

 gagactcttg ggatgactca ctgctgcatc aatcccatca tctatgcctt 1000

 cgttggggag aagttcagaa gcctttttca catagctctt ggctgtagga 1050

 ttgccccact ccaaaaacca gtgtgtggag gtccaggagt gagaccagga 1100

 aagaatgtga aagtgactac acaaggactc ctcgatggtc gtggaaaagg 1150

 aaagtcaatt ggcagagccc ctgaagccag tcttcaggac aaagaaggag 1200

 cctagagaca gaaatgacag atctctgctt tggaaatcac acgtctggct 1250

 tcacagatgt gtgattcaca gtgtgaatct tggtgtctac gttaccaggc 1300

 aggaaggctg agaggagaga gactccagct gggttggaaa acagtatttt 1350

 ccaaactacc ttccagttcc tcatttttga atacaggcat agagttcaga 1400

 ctttttttaa atagtaaaaa taaaattaaa gctgaaaact gcaacttgta 1450

 aatgtggtaa agagttagtt tgagttgcta tcatgtcaaa cgtgaaaatg 1500

 ctgtattagt cacagagata attctagctt tgagcttaag aattttgagc 1550

 aggtggtatg tttgggagac tgctgagtca acccaatagt tgttgattgg 1600

 caggagttgg aagtgtgtga tctgtgggca cattagccta tgtgcatgca 1650

 gcatctaagt aatgatgtcg tttgaatcac agtatacgct ccatcgctgt 1700

 catctcagct ggatctccat tctctcaggc ttgctgccaa aagccttttg 1750

 tgttttgttt tgtatcatta tgaagtcatg cgtttaatca cattcgagtg 1800

 tttcagtgct tcgcagatgt ccttgatgct catattgttc cctaatttgc 1850

 cagtgggaac tcctaaatca aattggcttc taatcaaagc ttttaaaccc 1900

 tattggtaaa gaatggaagg tggagaagct ccctgaagta agcaaagact 1950

 ttcctcttag tcgagccaag ttaagaatgt tcttatgttg cccagtgtgt 2000

 ttctgatctg atgcaagcaa gaaacactgg gcttctagaa ccaggcaact 2050

 tgggaactag actcccaagc tggactatgg ctctactttc aggccacatg 2100

 gctaaagaag gtttcagaaa gaagtgggga cagagcagaa ctttcacctt 2150

 catatatttg tatgatccta atgaatgcat aaaatgttaa gttgatggtg 2200

 atgaaatgta aatactgttt ttaacaacta tgatttggaa aataaatcaa 2250

 tgctataact atgttgataa aag 2273

<210> 5320
<211> 374
<212> PRT
<213> Homo sapien

<400> 5320
 Met Leu Ser Thr Ser Arg Ser Arg Phe Ile Arg Asn Thr Asn Glu
   1               5                  10                  15

 Ser Gly Glu Glu Val Thr Thr Phe Phe Asp Tyr Asp Tyr Gly Ala
                  20                  25                  30

 Pro Cys His Lys Phe Asp Val Lys Gln Ile Gly Ala Gln Leu Leu
                  35                  40                  45

 Pro Pro Leu Tyr Ser Leu Val Phe Ile Phe Gly Phe Val Gly Asn
                  50                  55                  60

 Met Leu Val Val Leu Ile Leu Ile Asn Cys Lys Lys Leu Lys Cys
                  65                  70                  75

 Leu Thr Asp Ile Tyr Leu Leu Asn Leu Ala Ile Ser Asp Leu Leu
                  80                  85                  90

 Phe Leu Ile Thr Leu Pro Leu Trp Ala His Ser Ala Ala Asn Glu
                  95                 100                 105

 Trp Val Phe Gly Asn Ala Met Cys Lys Leu Phe Thr Gly Leu Tyr
                 110                 115                 120

 His Ile Gly Tyr Phe Gly Gly Ile Phe Phe Ile Ile Leu Leu Thr
                 125                 130                 135

 Ile Asp Arg Tyr Leu Ala Ile Val His Ala Val Phe Ala Leu Lys
                 140                 145                 150

 Ala Arg Thr Val Thr Phe Gly Val Val Thr Ser Val Ile Thr Trp
                 155                 160                 165

 Leu Val Ala Val Phe Ala Ser Val Pro Gly Ile Ile Phe Thr Lys
                 170                 175                 180

 Cys Gln Lys Glu Asp Ser Val Tyr Val Cys Gly Pro Tyr Phe Pro
                 185                 190                 195

 Arg Gly Trp Asn Asn Phe His Thr Ile Met Arg Asn Ile Leu Gly
                 200                 205                 210

 Leu Val Leu Pro Leu Leu Ile Met Val Ile Cys Tyr Ser Gly Ile
                 215                 220                 225

 Leu Lys Thr Leu Leu Arg Cys Arg Asn Glu Lys Lys Arg His Arg
                 230                 235                 240

 Ala Val Arg Val Ile Phe Thr Ile Met Ile Val Tyr Phe Leu Phe
                 245                 250                 255

 Trp Thr Pro Tyr Asn Ile Val Ile Leu Leu Asn Thr Phe Gln Glu
                 260                 265                 270

 Phe Phe Gly Leu Ser Asn Cys Glu Ser Thr Ser Gln Leu Asp Gln
                 275                 280                 285

 Ala Thr Gln Val Thr Glu Thr Leu Gly Met Thr His Cys Cys Ile
                 290                 295                 300

 Asn Pro Ile Ile Tyr Ala Phe Val Gly Glu Lys Phe Arg Ser Leu
                 305                 310                 315

 Phe His Ile Ala Leu Gly Cys Arg Ile Ala Pro Leu Gln Lys Pro
                 320                 325                 330

 Val Cys Gly Gly Pro Gly Val Arg Pro Gly Lys Asn Val Lys Val
                 335                 340                 345

 Thr Thr Gln Gly Leu Leu Asp Gly Arg Gly Lys Gly Lys Ser Ile
                 350                 355                 360

 Gly Arg Ala Pro Glu Ala Ser Leu Gln Asp Lys Glu Gly Ala
                 365                 370

<210> 5321
<211> 2324
<212> DNA
<213> Homo sapien

<400> 5321
 ctccctttgg gcaaggacct gagacccttg tgctaagtca agaggctcaa 50

 tgggctgcag aagaactaga gaaggaccaa gcaaagccat gatatttcca 100

 tggaaatgtc agagcaccca gagggactta tggaacatct tcaagttgtg 150

 ggggtggaca atgctctgtt gtgatttcct ggcacatcat ggaaccgact 200

 gctggactta ccattattct gaaaaaccca tgaactggca aagggctaga 250

 agattctgcc gagacaatta cacagattta gttgccatac aaaacaaggc 300

 ggaaattgag tatctggaga agactctgcc tttcagtcgt tcttactact 350

 ggataggaat ccggaagata ggaggaatat ggacgtgggt gggaaccaac 400

 aaatctctta ctgaagaagc agagaactgg ggagatggtg agcccaacaa 450

 caagaagaac aaggaggact gcgtggagat ctatatcaag agaaacaaag 500

 atgcaggcaa atggaacgat gacgcctgcc acaaactaaa ggcagccctc 550

 tgttacacag cttcttgcca gccctggtca tgcagtggcc atggagaatg 600

 tgtagaaatc atcaataatt acacctgcaa ctgtgatgtg gggtactatg 650

 ggccccagtg tcagtttgtg attcagtgtg agcctttgga ggccccagag 700

 ctgggtacca tggactgtac tcaccctttg ggaaacttca gcttcagctc 750

 acagtgtgcc ttcagctgct ctgaaggaac aaacttaact gggattgaag 800

 aaaccacctg tggaccattt ggaaactggt catctccaga accaacctgt 850

 caagtgattc agtgtgagcc tctatcagca ccagatttgg ggatcatgaa 900

 ctgtagccat cccctggcca gcttcagctt tacctctgca tgtaccttca 950

 tctgctcaga aggaactgag ttaattggga agaagaaaac catttgtgaa 1000

 tcatctggaa tctggtcaaa tcctagtcca atatgtcaaa aattggacaa 1050

 aagtttctca atgattaagg agggtgatta taaccccctc ttcattccag 1100

 tggcagtcat ggttactgca ttctctgggt tggcatttat catttggctg 1150

 gcaaggagat taaaaaaagg caagaaatcc aagagaagta tgaatgaccc 1200

 atattaaatc gcccttggtg aaagaaaatt cttggaatac taaaaatcat 1250

 gagatccttt aaatccttcc atgaaacgtt ttgtgtggtg gcacctccta 1300

 cgtcaaacat gaagtgtgtt tccttcagtg catctgggaa gatttctacc 1350

 tgaccaacag ttccttcagc ttccatttcg cccctcattt atccctcaac 1400

 ccccagccca caggtgttta tacagctcag ctttttgtct tttctgagga 1450

 gaaacaaata agaccataaa gggaaaggat tcatgtggaa tataaagatg 1500

 gctgactttg ctctttcttg actcttgttt tcagtttcaa ttcagtgctg 1550

 tacttgatga cagacacttc taaatgaagt gcaaatttga tacatatgtg 1600

 aatatggact cagttttctt gcagatcaaa tttcacgtcg tcttctgtat 1650

 actgtggagg tacactctta tagaaagttc aaaaagtcta cgctctcctt 1700

 tctttctaac tccagtgaag taatggggtc ctgctcaagt tgaaagagtc 1750

 ctatttgcac tgtagcctcg ccgtctgtga attggaccat cctatttaac 1800

 tggcttcagc ctccccacct tcttcagcca cctctctttt tcagttggct 1850

 gacttccaca cctagcatct catgagtgcc aagcaaaagg agagaagaga 1900

 gaaatagcct gcgctgtttt ttagtttggg ggttttgctg tttcctttta 1950

 tgagacccat tcctatttct tatagtcaat gtttctttta tcacgatatt 2000

 attagtaaga aaacatcact gaaatgctag ctgcaagtga catctctttg 2050

 atgtcatatg gaagagttaa aacaggtgga gaaattcctt gattcacaat 2100

 gaaatgctct cctttcccct gcccccagac cttttatcca cttacctaga 2150

 ttctacatat tctttaaatt tcatctcagg cctccctcaa ccccaccact 2200

 tcttttataa ctagtccttt actaatccaa cccatgatga gctcctcttc 2250

 ctggcttctt actgaaaggt taccctgtaa catgcaattt tgcatttgaa 2300

 taaagcctgc tttttaagtg ttaa 2324

<210> 5322
<211> 372
<212> PRT
<213> Homo sapien

<400> 5322
 Met Ile Phe Pro Trp Lys Cys Gln Ser Thr Gln Arg Asp Leu Trp
   1               5                  10                  15

 Asn Ile Phe Lys Leu Trp Gly Trp Thr Met Leu Cys Cys Asp Phe
                  20                  25                  30

 Leu Ala His His Gly Thr Asp Cys Trp Thr Tyr His Tyr Ser Glu
                  35                  40                  45

 Lys Pro Met Asn Trp Gln Arg Ala Arg Arg Phe Cys Arg Asp Asn
                  50                  55                  60

 Tyr Thr Asp Leu Val Ala Ile Gln Asn Lys Ala Glu Ile Glu Tyr
                  65                  70                  75

 Leu Glu Lys Thr Leu Pro Phe Ser Arg Ser Tyr Tyr Trp Ile Gly
                  80                  85                  90

 Ile Arg Lys Ile Gly Gly Ile Trp Thr Trp Val Gly Thr Asn Lys
                  95                 100                 105

 Ser Leu Thr Glu Glu Ala Glu Asn Trp Gly Asp Gly Glu Pro Asn
                 110                 115                 120

 Asn Lys Lys Asn Lys Glu Asp Cys Val Glu Ile Tyr Ile Lys Arg
                 125                 130                 135

 Asn Lys Asp Ala Gly Lys Trp Asn Asp Asp Ala Cys His Lys Leu
                 140                 145                 150

 Lys Ala Ala Leu Cys Tyr Thr Ala Ser Cys Gln Pro Trp Ser Cys
                 155                 160                 165

 Ser Gly His Gly Glu Cys Val Glu Ile Ile Asn Asn Tyr Thr Cys
                 170                 175                 180

 Asn Cys Asp Val Gly Tyr Tyr Gly Pro Gln Cys Gln Phe Val Ile
                 185                 190                 195

 Gln Cys Glu Pro Leu Glu Ala Pro Glu Leu Gly Thr Met Asp Cys
                 200                 205                 210

 Thr His Pro Leu Gly Asn Phe Ser Phe Ser Ser Gln Cys Ala Phe
                 215                 220                 225

 Ser Cys Ser Glu Gly Thr Asn Leu Thr Gly Ile Glu Glu Thr Thr
                 230                 235                 240

 Cys Gly Pro Phe Gly Asn Trp Ser Ser Pro Glu Pro Thr Cys Gln
                 245                 250                 255

 Val Ile Gln Cys Glu Pro Leu Ser Ala Pro Asp Leu Gly Ile Met
                 260                 265                 270

 Asn Cys Ser His Pro Leu Ala Ser Phe Ser Phe Thr Ser Ala Cys
                 275                 280                 285

 Thr Phe Ile Cys Ser Glu Gly Thr Glu Leu Ile Gly Lys Lys Lys
                 290                 295                 300

 Thr Ile Cys Glu Ser Ser Gly Ile Trp Ser Asn Pro Ser Pro Ile
                 305                 310                 315

 Cys Gln Lys Leu Asp Lys Ser Phe Ser Met Ile Lys Glu Gly Asp
                 320                 325                 330

 Tyr Asn Pro Leu Phe Ile Pro Val Ala Val Met Val Thr Ala Phe
                 335                 340                 345

 Ser Gly Leu Ala Phe Ile Ile Trp Leu Ala Arg Arg Leu Lys Lys
                 350                 355                 360

 Gly Lys Lys Ser Lys Arg Ser Met Asn Asp Pro Tyr
                 365                 370

<210> 5323
<211> 1399
<212> DNA
<213> Homo sapien

<400> 5323
 agtgtgaaat cttcagagaa gaatttctct ttagttcttt gcaagaaggt 50

 agagataaag acactttttc aaaaatggca atggtatcag aattcctcaa 100

 gcaggcctgg tttattgaaa atgaagagca ggaatatgtt caaactgtga 150

 agtcatccaa aggtggtccc ggatcagcgg tgagccccta tcctaccttc 200

 aatccatcct cggatgtcgc tgccttgcat aaggccataa tggttaaagg 250

 tgtggatgaa gcaaccatca ttgacattct aactaagcga aacaatgcac 300

 agcgtcaaca gatcaaagca gcatatctcc aggaaacagg aaagcccctg 350

 gatgaaacac ttaagaaagc ccttacaggt caccttgagg aggttgtttt 400

 agctctgcta aaaactccag cgcaatttga tgctgatgaa cttcgtgctg 450

 ccatgaaggg ccttggaact gatgaagata ctctaattga gattttggca 500

 tcaagaacta acaaagaaat cagagacatt aacagggtct acagagagga 550

 actgaagaga gatctggcca aagacataac ctcagacaca tctggagatt 600

 ttcggaacgc tttgctttct cttgctaagg gtgaccgatc tgaggacttt 650

 ggtgtgaatg aagacttggc tgattcagat gccagggcct tgtatgaagc 700

 aggagaaagg agaaagggga cagacgtaaa cgtgttcaat accatcctta 750

 ccaccagaag ctatccacaa cttcgcagag tgtttcagaa atacaccaag 800

 tacagtaagc atgacatgaa caaagttctg gacctggagt tgaaaggtga 850

 cattgagaaa tgcctcacag ctatcgtgaa gtgcgccaca agcaaaccag 900

 ctttctttgc agagaagctt catcaagcca tgaaaggtgt tggaactcgc 950

 cataaggcat tgatcaggat tatggtttcc cgttctgaaa ttgacatgaa 1000

 tgatatcaaa gcattctatc agaagatgta tggtatctcc ctttgccaag 1050

 ccatcctgga tgaaaccaaa ggagattatg agaaaatcct ggtggctctt 1100

 tgtggaggaa actaaacatt cccttgatgg tctcaagcta tgatcagaag 1150

 actttaatta tatattttca tcctataagc ttaaatagga aagtttcttc 1200

 aacaggatta cagtgtagct acctacatgc tgaaaaatat agcctttaaa 1250

 tcatttttat attataactc tgtataatag agataagtcc attttttaaa 1300

 aatgttttcc ccaaaccata aaaccctata caagttgttc tagtaacaat 1350

 acatgagaaa gatgtctatg tagctgaaaa taaaatgacg tcacaagac 1399

<210> 5324
<211> 346
<212> PRT
<213> Homo sapien

<400> 5324
 Met Ala Met Val Ser Glu Phe Leu Lys Gln Ala Trp Phe Ile Glu
   1               5                  10                  15

 Asn Glu Glu Gln Glu Tyr Val Gln Thr Val Lys Ser Ser Lys Gly
                  20                  25                  30

 Gly Pro Gly Ser Ala Val Ser Pro Tyr Pro Thr Phe Asn Pro Ser
                  35                  40                  45

 Ser Asp Val Ala Ala Leu His Lys Ala Ile Met Val Lys Gly Val
                  50                  55                  60

 Asp Glu Ala Thr Ile Ile Asp Ile Leu Thr Lys Arg Asn Asn Ala
                  65                  70                  75

 Gln Arg Gln Gln Ile Lys Ala Ala Tyr Leu Gln Glu Thr Gly Lys
                  80                  85                  90

 Pro Leu Asp Glu Thr Leu Lys Lys Ala Leu Thr Gly His Leu Glu
                  95                 100                 105

 Glu Val Val Leu Ala Leu Leu Lys Thr Pro Ala Gln Phe Asp Ala
                 110                 115                 120

 Asp Glu Leu Arg Ala Ala Met Lys Gly Leu Gly Thr Asp Glu Asp
                 125                 130                 135

 Thr Leu Ile Glu Ile Leu Ala Ser Arg Thr Asn Lys Glu Ile Arg
                 140                 145                 150

 Asp Ile Asn Arg Val Tyr Arg Glu Glu Leu Lys Arg Asp Leu Ala
                 155                 160                 165

 Lys Asp Ile Thr Ser Asp Thr Ser Gly Asp Phe Arg Asn Ala Leu
                 170                 175                 180

 Leu Ser Leu Ala Lys Gly Asp Arg Ser Glu Asp Phe Gly Val Asn
                 185                 190                 195

 Glu Asp Leu Ala Asp Ser Asp Ala Arg Ala Leu Tyr Glu Ala Gly
                 200                 205                 210

 Glu Arg Arg Lys Gly Thr Asp Val Asn Val Phe Asn Thr Ile Leu
                 215                 220                 225

 Thr Thr Arg Ser Tyr Pro Gln Leu Arg Arg Val Phe Gln Lys Tyr
                 230                 235                 240

 Thr Lys Tyr Ser Lys His Asp Met Asn Lys Val Leu Asp Leu Glu
                 245                 250                 255

 Leu Lys Gly Asp Ile Glu Lys Cys Leu Thr Ala Ile Val Lys Cys
                 260                 265                 270

 Ala Thr Ser Lys Pro Ala Phe Phe Ala Glu Lys Leu His Gln Ala
                 275                 280                 285

 Met Lys Gly Val Gly Thr Arg His Lys Ala Leu Ile Arg Ile Met
                 290                 295                 300

 Val Ser Arg Ser Glu Ile Asp Met Asn Asp Ile Lys Ala Phe Tyr
                 305                 310                 315

 Gln Lys Met Tyr Gly Ile Ser Leu Cys Gln Ala Ile Leu Asp Glu
                 320                 325                 330

 Thr Lys Gly Asp Tyr Glu Lys Ile Leu Val Ala Leu Cys Gly Gly
                 335                 340                 345

 Asn


<210> 5325
<211> 1311
<212> DNA
<213> Homo sapien

<400> 5325
 gtaagtctgc tggcctccgc catcttagta aagtaacagt cccatgaaac 50

 aaagatgcag tcgggcactc actggagagt tctgggcctc tgcctcttat 100

 cagttggcgt ttgggggcaa gatggtaatg aagaaatggg tggtattaca 150

 cagacaccat ataaagtctc catctctgga accacagtaa tattgacatg 200

 ccctcagtat cctggatctg aaatactatg gcaacacaat gataaaaaca 250

 taggcggtga tgaggatgat aaaaacatag gcagtgatga ggatcacctg 300

 tcactgaagg aattttcaga attggagcaa agtggttatt atgtctgcta 350

 ccccagagga agcaaaccag aagatgcgaa cttttatctc tacctgaggg 400

 caagagtgtg tgagaactgc atggagatgg atgtgatgtc ggtggccaca 450

 attgtcatag tggacatctg catcactggg ggcttgctgc tgctggttta 500

 ctactggagc aagaatagaa aggccaaggc caagcctgtg acacgaggag 550

 cgggtgctgg cggcaggcaa aggggacaaa acaaggagag gccaccacct 600

 gttcccaacc cagactatga gcccatccgg aaaggccagc gggacctgta 650

 ttctggcctg aatcagagac gcatctgacc ctctggagaa cactgcctcc 700

 cgctggccca ggtctcctct ccagtccccc tgcgactccc tgtttcctgg 750

 gctagtcttg gaccccacga gagagaatcg ttcctcagcc tcatggtgaa 800

 ctcgcgccct ccagcctgat cccccgctcc ctcctccctg ccttctctgc 850

 tggtacccag tcctaaaata ttgctgcttc ctcttccttt gaagcatcat 900

 cagtagtcac accctcacag ctggcctgcc ctcttgccag gatatttatt 950

 tgtgctattc actcccttcc ctttggatgt aacttctccg ttcagttccc 1000

 tccttttctt gcatgtaagt tgtcccccat cccaaagtat tccatctact 1050

 tttctatcgc cgtccccttt tgcagccctc tctggggatg gactgggtaa 1100

 atgttgacag aggccctgcc ccgttcacag atcctggccc tgagccagcc 1150

 ctgtgctcct ccctccccca acactcccta ccaaccccct aatcccctac 1200

 tccctccaac cccccctccc actgtaggcc actggatggt catttggcat 1250

 ctccgtatat gtgctctggc tcctcagctg agagagaaaa aaataaactg 1300

 tatttggctg c 1311

<210> 5326
<211> 207
<212> PRT
<213> Homo sapien

<400> 5326
 Met Gln Ser Gly Thr His Trp Arg Val Leu Gly Leu Cys Leu Leu
   1               5                  10                  15

 Ser Val Gly Val Trp Gly Gln Asp Gly Asn Glu Glu Met Gly Gly
                  20                  25                  30

 Ile Thr Gln Thr Pro Tyr Lys Val Ser Ile Ser Gly Thr Thr Val
                  35                  40                  45

 Ile Leu Thr Cys Pro Gln Tyr Pro Gly Ser Glu Ile Leu Trp Gln
                  50                  55                  60

 His Asn Asp Lys Asn Ile Gly Gly Asp Glu Asp Asp Lys Asn Ile
                  65                  70                  75

 Gly Ser Asp Glu Asp His Leu Ser Leu Lys Glu Phe Ser Glu Leu
                  80                  85                  90

 Glu Gln Ser Gly Tyr Tyr Val Cys Tyr Pro Arg Gly Ser Lys Pro
                  95                 100                 105

 Glu Asp Ala Asn Phe Tyr Leu Tyr Leu Arg Ala Arg Val Cys Glu
                 110                 115                 120

 Asn Cys Met Glu Met Asp Val Met Ser Val Ala Thr Ile Val Ile
                 125                 130                 135

 Val Asp Ile Cys Ile Thr Gly Gly Leu Leu Leu Leu Val Tyr Tyr
                 140                 145                 150

 Trp Ser Lys Asn Arg Lys Ala Lys Ala Lys Pro Val Thr Arg Gly
                 155                 160                 165

 Ala Gly Ala Gly Gly Arg Gln Arg Gly Gln Asn Lys Glu Arg Pro
                 170                 175                 180

 Pro Pro Val Pro Asn Pro Asp Tyr Glu Pro Ile Arg Lys Gly Gln
                 185                 190                 195

 Arg Asp Leu Tyr Ser Gly Leu Asn Gln Arg Arg Ile
                 200                 205

<210> 5327
<211> 1279
<212> DNA
<213> Homo sapien

<400> 5327
 agaaactcag agaccaagtc cattgagaga ctgaggggaa agagaggaga 50

 gaaagaaaaa gagagtggga acagtaaaga gaaaggaaga caacctccag 100

 agaaagcccc cggagacgtc tctctgcaga gaggcggcag cacccggctc 150

 acctgcgaag cgcctgggaa gcgagtgccc ctaacatgcg gctgccgctg 200

 cttgtgtccg cgggagtcct gctggtggct ctcctgccct gcccgccatg 250

 cagggcgctc ctgagccgcg ggccggtccc gggagctcgg caggcgccgc 300

 agcaccctca gcccttggat ttcttccagc cgccgccgca gtccgagcag 350

 ccccagcagc cgcaggctcg gccggtcctg ctccgcatgg gagaggagta 400

 cttcctccgc ctggggaacc tcaacaagag cccggccgct cccctttcgc 450

 ccgcctcctc gctcctcgcc ggaggcagcg gcagccgccc ttcgccggaa 500

 caggcgaccg ccaacttttt ccgcgtgttg ctgcagcagc tgctgctgcc 550

 tcggcgctcg ctcgacagcc ccgcggctct cgcggagcgc ggcgctagga 600

 atgccctcgg cggccaccag gaggcaccgg agagagaaag gcggtccgag 650

 gagcctccca tctccctgga tctcaccttc cacctcctcc gggaagtctt 700

 ggaaatggcc agggccgagc agttagcaca gcaagctcac agcaacagga 750

 aactcatgga gattattggg aaataaaacg gtgcgtttgg ccaaaaagaa 800

 tctgcattta gcacaaaaaa aatttaaaaa aatacagtat tctgtaccat 850

 agcgctgctc ttatgccatt tgtttatttt tatatagctt gaaacataga 900

 gggagagagg gagagagcct atacccctta cttagcatgc acaaagtgta 950

 ttcacgtgca gcagcaacac aatgttattc gttttgtcta cgtttagttt 1000

 ccgtttccag gtgtttatag tggtgtttta aagagaatgt agacctgtga 1050

 gaaaacgttt tgtttgaaaa agcagacaga agtcactcaa ttgtttttgt 1100

 tgtggtctga gccaaagaga atgccattct cttgggtggg taagactaaa 1150

 tctgtaagct ctttgaaaca actttctctt gtaaacgttt cagtaataaa 1200

 acatctttcc agtccttggt cagtttggtt gtgtaagaga atgttgaata 1250

 cttatatttt taataaaagt tgcaaaggt 1279

<210> 5328
<211> 196
<212> PRT
<213> Homo sapien

<400> 5328
 Met Arg Leu Pro Leu Leu Val Ser Ala Gly Val Leu Leu Val Ala
   1               5                  10                  15

 Leu Leu Pro Cys Pro Pro Cys Arg Ala Leu Leu Ser Arg Gly Pro
                  20                  25                  30

 Val Pro Gly Ala Arg Gln Ala Pro Gln His Pro Gln Pro Leu Asp
                  35                  40                  45

 Phe Phe Gln Pro Pro Pro Gln Ser Glu Gln Pro Gln Gln Pro Gln
                  50                  55                  60

 Ala Arg Pro Val Leu Leu Arg Met Gly Glu Glu Tyr Phe Leu Arg
                  65                  70                  75

 Leu Gly Asn Leu Asn Lys Ser Pro Ala Ala Pro Leu Ser Pro Ala
                  80                  85                  90

 Ser Ser Leu Leu Ala Gly Gly Ser Gly Ser Arg Pro Ser Pro Glu
                  95                 100                 105

 Gln Ala Thr Ala Asn Phe Phe Arg Val Leu Leu Gln Gln Leu Leu
                 110                 115                 120

 Leu Pro Arg Arg Ser Leu Asp Ser Pro Ala Ala Leu Ala Glu Arg
                 125                 130                 135

 Gly Ala Arg Asn Ala Leu Gly Gly His Gln Glu Ala Pro Glu Arg
                 140                 145                 150

 Glu Arg Arg Ser Glu Glu Pro Pro Ile Ser Leu Asp Leu Thr Phe
                 155                 160                 165

 His Leu Leu Arg Glu Val Leu Glu Met Ala Arg Ala Glu Gln Leu
                 170                 175                 180

 Ala Gln Gln Ala His Ser Asn Arg Lys Leu Met Glu Ile Ile Gly
                 185                 190                 195

 Lys


<210> 5329
<211> 781
<212> DNA
<213> Homo sapien

<400> 5329
 acacagagag aaaggctaaa gttctctgga ggatgtggct gcagagcctg 50

 ctgctcttgg gcactgtggc ctgcagcatc tctgcacccg cccgctcgcc 100

 cagccccagc acgcagccct gggagcatgt gaatgccatc caggaggccc 150

 ggcgtctcct gaacctgagt agagacactg ctgctgagat gaatgaaaca 200

 gtagaagtca tctcagaaat gtttgacctc caggagccga cctgcctaca 250

 gacccgcctg gagctgtaca agcagggcct gcggggcagc ctcaccaagc 300

 tcaagggccc cttgaccatg atggccagcc actacaagca gcactgccct 350

 ccaaccccgg aaacttcctg tgcaacccag attatcacct ttgaaagttt 400

 caaagagaac ctgaaggact ttctgcttgt catccccttt gactgctggg 450

 agccagtcca ggagtgagac cggccagatg aggctggcca agccggggag 500

 ctgctctctc atgaaacaag agctagaaac tcaggatggt catcttggag 550

 ggaccaaggg gtgggccaca gccatggtgg gagtggcctg gacctgccct 600

 gggccacact gaccctgata caggcatggc agaagaatgg gaatatttta 650

 tactgacaga aatcagtaat atttatatat ttatattttt aaaatattta 700

 tttatttatt tatttaagtt catattccat atttattcaa gatgttttac 750

 cgtaataatt attattaaaa atatgcttct a 781

<210> 5330
<211> 144
<212> PRT
<213> Homo sapien

<400> 5330
 Met Trp Leu Gln Ser Leu Leu Leu Leu Gly Thr Val Ala Cys Ser
   1               5                  10                  15

 Ile Ser Ala Pro Ala Arg Ser Pro Ser Pro Ser Thr Gln Pro Trp
                  20                  25                  30

 Glu His Val Asn Ala Ile Gln Glu Ala Arg Arg Leu Leu Asn Leu
                  35                  40                  45

 Ser Arg Asp Thr Ala Ala Glu Met Asn Glu Thr Val Glu Val Ile
                  50                  55                  60

 Ser Glu Met Phe Asp Leu Gln Glu Pro Thr Cys Leu Gln Thr Arg
                  65                  70                  75

 Leu Glu Leu Tyr Lys Gln Gly Leu Arg Gly Ser Leu Thr Lys Leu
                  80                  85                  90

 Lys Gly Pro Leu Thr Met Met Ala Ser His Tyr Lys Gln His Cys
                  95                 100                 105

 Pro Pro Thr Pro Glu Thr Ser Cys Ala Thr Gln Ile Ile Thr Phe
                 110                 115                 120

 Glu Ser Phe Lys Glu Asn Leu Lys Asp Phe Leu Leu Val Ile Pro
                 125                 130                 135

 Phe Asp Cys Trp Glu Pro Val Gln Glu
                 140

<210> 5331
<211> 3900
<212> DNA
<213> Homo sapien

<400> 5331
 cgatggccct gcccagtccc agacagaacc tactacgtgc ggcggcagct 50

 ggggcgggaa ggcgggcgct gggggcgctg cggccgctgc agcgcagggt 100

 ccacctggtc ggctgcacct gtggaggagg aggtggattt caggcttccc 150

 gtagactgga agaatcggct caaaaccgct tgcctcgcag gggctgagct 200

 ggaggcagcg aggccgcccg acgcaggctt ccggcgagac atggcagggc 250

 aaggatggca gcccggcggc agggcccggc gaggagcgcg aacccgcggc 300

 cgcagttccc aggcgtctgc gggcgcgagc acgccgcgac cctgcgtgcg 350

 ccggggcggg ggggcggggc ctcgcctgca caaataggga cgagggggcg 400

 gggcggccac aatttcgcgc caaacttgac cgcgcgttct gctgtaacga 450

 gcgggctcgg aggtcctccc gctgctgtca tggttggttc gctaaactgc 500

 atcgtcgctg tgtcccagaa catgggcatc ggcaagaacg gggacctgcc 550

 ctggccaccg ctcaggaatg aattcagata tttccagaga atgaccacaa 600

 cctcttcagt agaaggtaaa cagaatctgg tgattatggg taagaagacc 650

 tggttctcca ttcctgagaa gaatcgacct ttaaagggta gaattaattt 700

 agttctcagc agagaactca aggaacctcc acaaggagct cattttcttt 750

 ccagaagtct agatgatgcc ttaaaactta ctgaacaacc agaattagca 800

 aataaagtag acatggtctg gatagttggt ggcagttctg tttataagga 850

 agccatgaat cacccaggcc atcttaaact atttgtgaca aggatcatgc 900

 aagactttga aagtgacacg ttttttccag aaattgattt ggagaaatat 950

 aaacttctgc cagaataccc aggtgttctc tctgatgtcc aggaggagaa 1000

 aggcattaag tacaaatttg aagtatatga gaagaatgat taatatgaag 1050

 gtgttttcta gtttaagttg ttccccctcc ctctgaaaaa agtatgtatt 1100

 tttacattag aaaaggtttt ttgttgactt tagatctata attatttcta 1150

 agcaacttgt ttttattccc cactactctt ctctctatca gataccattt 1200

 atgagacatt cttgctataa ctaagtgctt ctccaagacc ccaactgagt 1250

 ccccagcacc tgctacagtg agctgccatt ccacacccat cacatgtggc 1300

 actcttgcca gtccttgaca ttgtcgggct tttcacatgt tggtaatatt 1350

 tattaaagat gaagatccac atacccttca actgagcagt ttcactagtg 1400

 gaaataccaa aagcttccta cgtgtatatc cagaggtttg tagataaatg 1450

 ttgccacctt gtttgtaaca gtgaaaaatt gaaaacaacc tggaagtcca 1500

 gtgatgggaa aatgagtatg tttctgtctt agattgggga acccaaagca 1550

 gattgcaaga ctgaaatttc agtgaaagca gtgtatttgc taggtcatac 1600

 cagaaatcat caattgaggt acggagaaac tgaactgaga aggtaagaaa 1650

 agcaatttaa agtcagcgag caggttctca ttgataacaa gctccatact 1700

 gctgagatac agggaaatgg aggggggaaa gctggagtat tgatcccgcc 1750

 cccctccttg gttgtcagct ccctgtcctg tgtgtgggcg gaacatagtc 1800

 cagctgctct atagcaagtc tcaggtgttt gcagtaagaa gctgctggca 1850

 tgcacgggaa cagtgaatgc caaacactta aagcaattcg atgtttaagt 1900

 atgtaagttc tttttttttt agacagcgtt tcgctcttgt tgcccaggct 1950

 agcatgcaat ggtgtgacct cggcttactg caacctccgc cttcccagat 2000

 tcaagcgatt ctcctgcctc aggctcccaa gtagctagga ccaggtgcgc 2050

 gccaccacgc ccggctaatt tttgtatttt gtatttttag tagagatggg 2100

 gtttcaccat gttggtcagg ctagtctcga actcgtgacc gcaagcgatt 2150

 cacccacctc agcctcccaa agtgctggga ttaccggctt gagccaccac 2200

 acccggcaca tcttcattct ttttatgtag taaaaagtat aaggccacac 2250

 atggtttatt tgaagtattt tataatttaa aaaaatacag aagcaggaaa 2300

 accaattata agttcaagtg agggatgatg gttgcttgaa ccaaagggtt 2350

 gcatgtagta agaaattgtg atttaagata tattttaaag ttataagtag 2400

 caggatattc tgatggagtt tgactttggt tttgggccca gggagtttca 2450

 gatgcctttg agaaatgaat gaagtagaga gaaaataaaa gaaaaaccag 2500

 ccaggcacag tggctcacac ctgtaatccc agcgctttgg gaggctaagg 2550

 caggcagatc acttgagacc agcttgggca acatggcaaa gccccatctc 2600

 tacaaaaaac acaaaaatta gctgggcatt gtggcgcaca cctgtattcc 2650

 catctagtca ggaagctgag atggaagaat taattgagcc cacgagttca 2700

 aggctgcagt gagtcgtgat tgtgccactg cactccagcc ggggtgacag 2750

 aagagacctt gtctcgaaaa cgaatctgaa aacaatggaa ccatgccttc 2800

 ataattctag aaagttattt tcaactgata aatctatatt cacccaaata 2850

 atcaagggtg aaggtaaaat aatacatttt tagacaagca aagactcagg 2900

 ggttacctcc atgtgccctt tttagggaag ctgttggaga aaatactcca 2950

 gcaaaatgaa ggagtacaca aaccagagaa tgacatgaat ccagcaaata 3000

 ggatccaaca caggcaatat tccagctatg gagctagctt taaaaaggaa 3050

 cagtaaaaat attaatcggt tagctgggtg gaatggccca tgcctgtagt 3100

 cccagctact caggaggctc agcagcagga cgacttgagc ccaagagttc 3150

 cagaccagcc tggccacctt agtgagatcc cttctcttaa aaataataac 3200

 ttattgccag atttggggca tttggaaaga agttcattga agataaagca 3250

 aaagtaaaaa aaaaaaaaaa aaaaacaagg ggaaagggtt ggttaggcaa 3300

 tcattctagg gcagaaagaa gtacaggata ggaagagcat aatacactgt 3350

 ttttctcaac aaggagcagt atgtacacag tcataatgat gtgactgctt 3400

 agcccctaaa tatggtaact actctgggac aatatgggag gaaaagtgaa 3450

 gattgtgatg gtgtaagagc taatcctcat ctgtcatatc cagaaatcac 3500

 tatataatat ataataatga aatgactaag ttatgtgagg aaaaaaacag 3550

 aagacattgc taaaagagtt aaaagtcatt gctctggaga attaggaggg 3600

 atggggcagg ggactgttag gatgcattat aaactgaaaa gcctttttaa 3650

 aattttatgt attaatatat gcattcactt gaaaaactaa aaaaaaacaa 3700

 taatttggaa aaacccatga aggtaactaa cggaaggaaa aactaagaga 3750

 atgaaaagta tttgcctctg gaaagaacaa ctggcaggac tgttgttttc 3800

 attgtaagac ttttggagcc atttaattgt acttaaccat tttcatctat 3850

 ttctttaata agaacaattc catcttaata aagagttaca cttgttaata 3900

<210> 5332
<211> 187
<212> PRT
<213> Homo sapien

<400> 5332
 Met Val Gly Ser Leu Asn Cys Ile Val Ala Val Ser Gln Asn Met
   1               5                  10                  15

 Gly Ile Gly Lys Asn Gly Asp Leu Pro Trp Pro Pro Leu Arg Asn
                  20                  25                  30

 Glu Phe Arg Tyr Phe Gln Arg Met Thr Thr Thr Ser Ser Val Glu
                  35                  40                  45

 Gly Lys Gln Asn Leu Val Ile Met Gly Lys Lys Thr Trp Phe Ser
                  50                  55                  60

 Ile Pro Glu Lys Asn Arg Pro Leu Lys Gly Arg Ile Asn Leu Val
                  65                  70                  75

 Leu Ser Arg Glu Leu Lys Glu Pro Pro Gln Gly Ala His Phe Leu
                  80                  85                  90

 Ser Arg Ser Leu Asp Asp Ala Leu Lys Leu Thr Glu Gln Pro Glu
                  95                 100                 105

 Leu Ala Asn Lys Val Asp Met Val Trp Ile Val Gly Gly Ser Ser
                 110                 115                 120

 Val Tyr Lys Glu Ala Met Asn His Pro Gly His Leu Lys Leu Phe
                 125                 130                 135

 Val Thr Arg Ile Met Gln Asp Phe Glu Ser Asp Thr Phe Phe Pro
                 140                 145                 150

 Glu Ile Asp Leu Glu Lys Tyr Lys Leu Leu Pro Glu Tyr Pro Gly
                 155                 160                 165

 Val Leu Ser Asp Val Gln Glu Glu Lys Gly Ile Lys Tyr Lys Phe
                 170                 175                 180

 Glu Val Tyr Glu Lys Asn Asp
                 185

<210> 5333
<211> 2518
<212> DNA
<213> Homo sapien

<400> 5333
 ccagcagtgg ctgcaccatg cacgtgaacg gcaaagtggc gctggtgacc 50

 ggcgcggctc agggcatagg cagagccttt gcagaggcgc tgctgcttaa 100

 gggcgccaag gtagcgctgg tggattggaa tcttgaagca ggtgtacagt 150

 gtaaagctgc cctgcatgag caatttgaac ctcagaagac tctgttcatc 200

 cagtgcgatg tggctgacca gcaacaactg agagacactt ttagaaaagt 250

 tgtagaccac tttggaagac tggacatttt ggtcaataat gctggagtga 300

 ataatgagaa aaactgggaa aaaactctgc aaattaattt ggtttctgtt 350

 atcagtggaa cctatcttgg tttggattac atgagtaagc aaaatggagg 400

 tgaaggcggc atcattatca atatgtcatc tttagcagga ctcatgcccg 450

 ttgcacagca gccggtttat tgtgcttcaa agcatggcat agttggattc 500

 acacgctcag cagcgttggc tgctaatctt atgaacagtg gtgtgagact 550

 gaatgccatt tgtccaggct ttgttaacac agccatcctt gaatcaattg 600

 aaaaagaaga aaacatggga caatatatag aatataagga tcatatcaag 650

 gatatgatta aatactatgg aattttggac ccaccattga ttgccaatgg 700

 attgataaca ctcattgaag atgatgcttt aaatggtgct attatgaaga 750

 tcacaacttc taagggaatt cattttcaag actatgatac aactccattt 800

 caagcaaaaa cccaatgaac agcttatgtg ttagccatag ctgaaaataa 850

 gcacaaatag cttatattca gatcctatct tcatttgaat atagctttta 900

 aatgaaatgt tacagtttga agttttcctt catgcacttg gtgataaacg 950

 ttttctaaat ttttagttaa gtatatggat aaaaagttat gaactattaa 1000

 aaatgtgatg tggaccaaag gctaggttgt aatcttgata gtctaaaaaa 1050

 tgatcaaaac aaatgatttt caaggaatat tcaatattct gcctttcaga 1100

 aagtgtattt atatctgtgc ttcataaata ttaatgttct tcagaacatc 1150

 attttaaagg agatacttga attgttattt aaatcaaacc agatgtaaaa 1200

 cactcacata caagttcata ctttaaaaga ggaaagctac ttaacaatga 1250

 caaatatttc acaataataa tttttactta tataccatct ttcaactgaa 1300

 catttcagtt cttccaagag cttcttagag tagtatattt tgggggcagt 1350

 caaggaataa actacagtgt aaacatatcc cagatgaaaa ctgctgtatg 1400

 gaaaaatgac agaaagtaac tgattgacac tgttgattca cagttcagcc 1450

 tcctatctgg gaaagacatt tctttcctct gctcacttta agaactttta 1500

 ccgactccaa aaatctcagg aattaaactt ttaacagtta cagcaataaa 1550

 gaatagttag tactccaaaa atattatatt taagatgctc aacaagaaaa 1600

 aaatgcaaat gtaatatttt tttcaaatta cttctttatt gacttgtcca 1650

 aatttcaaaa gtgcctaccc ttcaataaaa cttttttatt ctgatctcca 1700

 taaattactt agtcttctat gtatagctat caaggaaata aaaccaattt 1750

 tgccacagcc acaactgtaa atgtttttgt acccatgctg aaactcataa 1800

 caacacagac ataaaaatag ctgtgaggtt ttgctttttt tgttgtcagc 1850

 tatcttaaga atcattaaat acacctgctt tgggtaaaac tctttgcaag 1900

 cagtaattaa cactagtaac agtgaaagca caagatttcc aaatcagtcg 1950

 ttttctcaaa aaaatatcgt ataagtgact catcctgtct gctaactcca 2000

 gacctcccag cttgaagcca aatctttcca tgtgagattg atatggattt 2050

 cctagaagta ctggaatgtt gtcatatctt gccctatttt aattctgcta 2100

 tagaaaacaa ttgccttcac ttttaaggag taatttgaat attaataact 2150

 ctggtctaga ttttcatata atgtattaaa gacaaagtag tgaacatcaa 2200

 tgaacatctg atagagataa actgtaatca ggcataagct tgtttgtatg 2250

 ttctggcagt gactaatcag taaatgatgt cggtttgccc agtatcactt 2300

 atcttctgta tttttcctct gtcgtgtaaa tagtataacc ttttcattta 2350

 tggacaattt tttggactag tagccttcaa tatacattct gctttgaatt 2400

 aattttttca aatcaataaa ttatgtagac atttaaaatc aaatatcaag 2450

 tagaattgaa aaatgtgagt tacataagtt aaaaacttac tttaaatctt 2500

 accttctata ggtagctc 2518

<210> 5334
<211> 266
<212> PRT
<213> Homo sapien

<400> 5334
 Met His Val Asn Gly Lys Val Ala Leu Val Thr Gly Ala Ala Gln
   1               5                  10                  15

 Gly Ile Gly Arg Ala Phe Ala Glu Ala Leu Leu Leu Lys Gly Ala
                  20                  25                  30

 Lys Val Ala Leu Val Asp Trp Asn Leu Glu Ala Gly Val Gln Cys
                  35                  40                  45

 Lys Ala Ala Leu His Glu Gln Phe Glu Pro Gln Lys Thr Leu Phe
                  50                  55                  60

 Ile Gln Cys Asp Val Ala Asp Gln Gln Gln Leu Arg Asp Thr Phe
                  65                  70                  75

 Arg Lys Val Val Asp His Phe Gly Arg Leu Asp Ile Leu Val Asn
                  80                  85                  90

 Asn Ala Gly Val Asn Asn Glu Lys Asn Trp Glu Lys Thr Leu Gln
                  95                 100                 105

 Ile Asn Leu Val Ser Val Ile Ser Gly Thr Tyr Leu Gly Leu Asp
                 110                 115                 120

 Tyr Met Ser Lys Gln Asn Gly Gly Glu Gly Gly Ile Ile Ile Asn
                 125                 130                 135

 Met Ser Ser Leu Ala Gly Leu Met Pro Val Ala Gln Gln Pro Val
                 140                 145                 150

 Tyr Cys Ala Ser Lys His Gly Ile Val Gly Phe Thr Arg Ser Ala
                 155                 160                 165

 Ala Leu Ala Ala Asn Leu Met Asn Ser Gly Val Arg Leu Asn Ala
                 170                 175                 180

 Ile Cys Pro Gly Phe Val Asn Thr Ala Ile Leu Glu Ser Ile Glu
                 185                 190                 195

 Lys Glu Glu Asn Met Gly Gln Tyr Ile Glu Tyr Lys Asp His Ile
                 200                 205                 210

 Lys Asp Met Ile Lys Tyr Tyr Gly Ile Leu Asp Pro Pro Leu Ile
                 215                 220                 225

 Ala Asn Gly Leu Ile Thr Leu Ile Glu Asp Asp Ala Leu Asn Gly
                 230                 235                 240

 Ala Ile Met Lys Ile Thr Thr Ser Lys Gly Ile His Phe Gln Asp
                 245                 250                 255

 Tyr Asp Thr Thr Pro Phe Gln Ala Lys Thr Gln
                 260                 265

<210> 5335
<211> 4909
<212> DNA
<213> Homo sapien

<400> 5335
 tagacgcacc ctctgaagat ggtgactccc tcctgagaag ctggacccct 50

 tggtaaaaga caaggccttc tccaagaaga atatgaaagt gttactcaga 100

 cttatttgtt tcatagctct actgatttct tctctggagg ctgataaatg 150

 caaggaacgt gaagaaaaaa taattttagt gtcatctgca aatgaaattg 200

 atgttcgtcc ctgtcctctt aacccaaatg aacacaaagg cactataact 250

 tggtataaag atgacagcaa gacacctgta tctacagaac aagcctccag 300

 gattcatcaa cacaaagaga aactttggtt tgttcctgct aaggtggagg 350

 attcaggaca ttactattgc gtggtaagaa attcatctta ctgcctcaga 400

 attaaaataa gtgcaaaatt tgtggagaat gagcctaact tatgttataa 450

 tgcacaagcc atatttaagc agaaactacc cgttgcagga gacggaggac 500

 ttgtgtgccc ttatatggag ttttttaaaa atgaaaataa tgagttacct 550

 aaattacagt ggtataagga ttgcaaacct ctacttcttg acaatataca 600

 ctttagtgga gtcaaagata ggctcatcgt gatgaatgtg gctgaaaagc 650

 atagagggaa ctatacttgt catgcatcct acacatactt gggcaagcaa 700

 tatcctatta cccgggtaat agaatttatt actctagagg aaaacaaacc 750

 cacaaggcct gtgattgtga gcccagctaa tgagacaatg gaagtagact 800

 tgggatccca gatacaattg atctgtaatg tcaccggcca gttgagtgac 850

 attgcttact ggaagtggaa tgggtcagta attgatgaag atgacccagt 900

 gctaggggaa gactattaca gtgtggaaaa tcctgcaaac aaaagaagga 950

 gtaccctcat cacagtgctt aatatatcgg aaattgaaag tagattttat 1000

 aaacatccat ttacctgttt tgccaagaat acacatggta tagatgcagc 1050

 atatatccag ttaatatatc cagtcactaa tttccagaag cacatgattg 1100

 gtatatgtgt cacgttgaca gtcataattg tgtgttctgt tttcatctat 1150

 aaaatcttca agattgacat tgtgctttgg tacagggatt cctgctatga 1200

 ttttctccca ataaaagctt cagatggaaa gacctatgac gcatatatac 1250

 tgtatccaaa gactgttggg gaagggtcta cctctgactg tgatattttt 1300

 gtgtttaaag tcttgcctga ggtcttggaa aaacagtgtg gatataagct 1350

 gttcatttat ggaagggatg actacgttgg ggaagacatt gttgaggtca 1400

 ttaatgaaaa cgtaaagaaa agcagaagac tgattatcat tttagtcaga 1450

 gaaacatcag gcttcagctg gctgggtggt tcatctgaag agcaaatagc 1500

 catgtataat gctcttgttc aggatggaat taaagttgtc ctgcttgagc 1550

 tggagaaaat ccaagactat gagaaaatgc cagaatcgat taaattcatt 1600

 aagcagaaac atggggctat ccgctggtca ggggacttta cacagggacc 1650

 acagtctgca aagacaaggt tctggaagaa tgtcaggtac cacatgccag 1700

 tccagcgacg gtcaccttca tctaaacacc agttactgtc accagccact 1750

 aaggagaaac tgcaaagaga ggctcacgtg cctctcgggt agcatggaga 1800

 agttgccaag agttctttag gtgcctcctg tcttatggcg ttgcaggcca 1850

 ggttatgcct catgctgact tgcagagttc atggaatgta actatatcat 1900

 cctttatccc tgaggtcacc tggaatcaga ttattaaggg aataagccat 1950

 gacgtcaata gcagcccagg gcacttcaga gtagagggct tgggaagatc 2000

 ttttaaaaag gcagtaggcc cggtgtggtg gctcacgcct ataatcccag 2050

 cactttggga ggctgaagtg ggtggatcac cagaggtcag gagttcgaga 2100

 ccagcccagc caacatggca aaaccccatc tctactaaaa atacaaaaat 2150

 gagctaggca tggtggcaca cgcctgtaat cccagctaca cctgaggctg 2200

 aggcaggaga attgcttgaa ccggggagac ggaggttgca gtgagccgag 2250

 tttgggccac tgcactctag cctggcaaca gagcaagact ccgtctcaaa 2300

 aaaagggcaa taaatgccct ctctgaatgt ttgaactgcc aagaaaaggc 2350

 atggagacag cgaactagaa gaaagggcaa gaaggaaata gccaccgtct 2400

 acagatggct tagttaagtc atccacagcc caagggcggg gctatgcctt 2450

 gtctggggac cctgtagagt cactgaccct ggagcggctc tcctgagagg 2500

 tgctgcaggc aaagtgagac tgacacctca ctgaggaagg gagacatatt 2550

 cttggagaac tttccatctg cttgtatttt ccatacacat ccccagccag 2600

 aagttagtgt ccgaagaccg aattttattt tacagagctt gaaaactcac 2650

 ttcaatgaac aaagggattc tccaggattc caaagttttg aagtcatctt 2700

 agctttccac aggagggaga gaacttaaaa aagcaacagt agcagggaat 2750

 tgatccactt cttaatgctt tcctccctgg catgaccatc ctgtcctttg 2800

 ttattatcct gcattttacg tctttggagg aacagctccc tagtggcttc 2850

 ctccgtctgc aatgtccctt gcacagccca cacatgaacc atccttccca 2900

 tgatgccgct cttctgtcat cccgctcctg ctgaaacacc tcccaggggc 2950

 tccacctgtt caggagctga agcccatgct ttcccaccag catgtcactc 3000

 ccagaccacc tccctgccct gtcctccagc ttcccctcgc tgtcctgctg 3050

 tgtgaattcc caggttggcc tggtggccat gtcgcctgcc cccagcactc 3100

 ctctgtctct gctcttgcct cgacccttcc tcctcctttg cctaggaggc 3150

 cttctcgcat tttctctagc tgatcagaat tttaccaaaa ttcagaacat 3200

 cctccaattc cacagtctct gggagacttt ccctaagagg cgacttcctc 3250

 tccagccttc tctctctggt caggcccact gcagagatgg tggtgagcac 3300

 atctgggagg ctggtctccc tccagctgga attgctgctc tctgagggag 3350

 aggctgtggt ggctgtctct gtccctcact gccttccagg agcaatttgc 3400

 acatgtaaca tagatttatg taatgcttta tgtttaaaaa cattccccaa 3450

 ttatcttatt taatttttgc aattattcta attttatata tagagaaagt 3500

 gacctatttt ttaaaaaaat cacactctaa gttctattga acctaggact 3550

 tgagcctcca tttctggctt ctagtctggt gttctgagta cttgatttca 3600

 ggtcaataac ggtcccccct cactccacac tggcacgttt gtgagaagaa 3650

 atgacatttt gctaggaagt gaccgagtct aggaatgctt ttattcaaga 3700

 caccaaattc caaacttcta aatgttggaa ttttcaaaaa ttgtgtttag 3750

 attttatgaa aaactcttct actttcatct attctttccc tagaggcaaa 3800

 catttcttaa aatgtttcat tttcattaaa aatgaaagcc aaatttatat 3850

 gccaccgatt gcaggacaca agcacagttt taagagttgt atgaacatgg 3900

 agaggacttt tggtttttat atttctcgta tttaatatgg gtgaacacca 3950

 acttttattt ggaataataa ttttcctcct aaacaaaaac acattgagtt 4000

 taagtctctg actcttgcct ttccacctgc tttctcctgg gcccgctttg 4050

 cctgcttgaa ggaacagtgc tgttctggag ctgctgttcc aacagacagg 4100

 gcctagcttt catttgacac acagactaca gccagaagcc catggagcag 4150

 ggatgtcacg tcttgaaaag cctattagat gttttacaaa tttaattttg 4200

 cagattattt tagtctgtca tccagaaaat gtgtcagcat gcatagtgct 4250

 aagaaagcaa gccaatttgg aaacttaggt tagtgacaaa attggccaga 4300

 gagtgggggt gatgatgacc aagaattaca agtagaatgg cagctggaat 4350

 ttaaggaggg acaagaatca atggataagc gtgggtggag gaagatccaa 4400

 acagaaaagt gcaaagttat tccccatctt ccaagggttg aattctggag 4450

 gaagaagaca cattcctagt tccccgtgaa cttcctttga cttattgtcc 4500

 ccactaaaac aaaacaaaaa acttttaatg ccttccacat taattagatt 4550

 ttcttgcagt ttttttatgg cattttttta aagatgccct aagtgttgaa 4600

 gaagagtttg caaatgcaac aaaatattta attaccggtt gttaaaactg 4650

 gtttagcaca atttatattt tccctctctt gcctttctta tttgcaataa 4700

 aaggtattga gccatttttt aaatgacatt tttgataaat tatgtttgta 4750

 ctagttgatg aaggagtttt ttttaacctg tttatataat tttgcagcag 4800

 aagccaaatt ttttgtatat taaagcacca aattcatgta cagcatgcat 4850

 cacggatcaa tagactgtac ttattttcca ataaaatttt caaactttgt 4900

 actgttaaa 4909

<210> 5336
<211> 569
<212> PRT
<213> Homo sapien

<400> 5336
 Met Lys Val Leu Leu Arg Leu Ile Cys Phe Ile Ala Leu Leu Ile
   1               5                  10                  15

 Ser Ser Leu Glu Ala Asp Lys Cys Lys Glu Arg Glu Glu Lys Ile
                  20                  25                  30

 Ile Leu Val Ser Ser Ala Asn Glu Ile Asp Val Arg Pro Cys Pro
                  35                  40                  45

 Leu Asn Pro Asn Glu His Lys Gly Thr Ile Thr Trp Tyr Lys Asp
                  50                  55                  60

 Asp Ser Lys Thr Pro Val Ser Thr Glu Gln Ala Ser Arg Ile His
                  65                  70                  75

 Gln His Lys Glu Lys Leu Trp Phe Val Pro Ala Lys Val Glu Asp
                  80                  85                  90

 Ser Gly His Tyr Tyr Cys Val Val Arg Asn Ser Ser Tyr Cys Leu
                  95                 100                 105

 Arg Ile Lys Ile Ser Ala Lys Phe Val Glu Asn Glu Pro Asn Leu
                 110                 115                 120

 Cys Tyr Asn Ala Gln Ala Ile Phe Lys Gln Lys Leu Pro Val Ala
                 125                 130                 135

 Gly Asp Gly Gly Leu Val Cys Pro Tyr Met Glu Phe Phe Lys Asn
                 140                 145                 150

 Glu Asn Asn Glu Leu Pro Lys Leu Gln Trp Tyr Lys Asp Cys Lys
                 155                 160                 165

 Pro Leu Leu Leu Asp Asn Ile His Phe Ser Gly Val Lys Asp Arg
                 170                 175                 180

 Leu Ile Val Met Asn Val Ala Glu Lys His Arg Gly Asn Tyr Thr
                 185                 190                 195

 Cys His Ala Ser Tyr Thr Tyr Leu Gly Lys Gln Tyr Pro Ile Thr
                 200                 205                 210

 Arg Val Ile Glu Phe Ile Thr Leu Glu Glu Asn Lys Pro Thr Arg
                 215                 220                 225

 Pro Val Ile Val Ser Pro Ala Asn Glu Thr Met Glu Val Asp Leu
                 230                 235                 240

 Gly Ser Gln Ile Gln Leu Ile Cys Asn Val Thr Gly Gln Leu Ser
                 245                 250                 255

 Asp Ile Ala Tyr Trp Lys Trp Asn Gly Ser Val Ile Asp Glu Asp
                 260                 265                 270

 Asp Pro Val Leu Gly Glu Asp Tyr Tyr Ser Val Glu Asn Pro Ala
                 275                 280                 285

 Asn Lys Arg Arg Ser Thr Leu Ile Thr Val Leu Asn Ile Ser Glu
                 290                 295                 300

 Ile Glu Ser Arg Phe Tyr Lys His Pro Phe Thr Cys Phe Ala Lys
                 305                 310                 315

 Asn Thr His Gly Ile Asp Ala Ala Tyr Ile Gln Leu Ile Tyr Pro
                 320                 325                 330

 Val Thr Asn Phe Gln Lys His Met Ile Gly Ile Cys Val Thr Leu
                 335                 340                 345

 Thr Val Ile Ile Val Cys Ser Val Phe Ile Tyr Lys Ile Phe Lys
                 350                 355                 360

 Ile Asp Ile Val Leu Trp Tyr Arg Asp Ser Cys Tyr Asp Phe Leu
                 365                 370                 375

 Pro Ile Lys Ala Ser Asp Gly Lys Thr Tyr Asp Ala Tyr Ile Leu
                 380                 385                 390

 Tyr Pro Lys Thr Val Gly Glu Gly Ser Thr Ser Asp Cys Asp Ile
                 395                 400                 405

 Phe Val Phe Lys Val Leu Pro Glu Val Leu Glu Lys Gln Cys Gly
                 410                 415                 420

 Tyr Lys Leu Phe Ile Tyr Gly Arg Asp Asp Tyr Val Gly Glu Asp
                 425                 430                 435

 Ile Val Glu Val Ile Asn Glu Asn Val Lys Lys Ser Arg Arg Leu
                 440                 445                 450

 Ile Ile Ile Leu Val Arg Glu Thr Ser Gly Phe Ser Trp Leu Gly
                 455                 460                 465

 Gly Ser Ser Glu Glu Gln Ile Ala Met Tyr Asn Ala Leu Val Gln
                 470                 475                 480

 Asp Gly Ile Lys Val Val Leu Leu Glu Leu Glu Lys Ile Gln Asp
                 485                 490                 495

 Tyr Glu Lys Met Pro Glu Ser Ile Lys Phe Ile Lys Gln Lys His
                 500                 505                 510

 Gly Ala Ile Arg Trp Ser Gly Asp Phe Thr Gln Gly Pro Gln Ser
                 515                 520                 525

 Ala Lys Thr Arg Phe Trp Lys Asn Val Arg Tyr His Met Pro Val
                 530                 535                 540

 Gln Arg Arg Ser Pro Ser Ser Lys His Gln Leu Leu Ser Pro Ala
                 545                 550                 555

 Thr Lys Glu Lys Leu Gln Arg Glu Ala His Val Pro Leu Gly
                 560                 565

<210> 5337
<211> 4045
<212> DNA
<213> Homo sapien

<400> 5337
 gcagccagag ctcagcaggg ccctggagag atggccacgg tcccagcacc 50

 ggggaggact ggagagcgcg cgctgccacc gccccatgtc tcagccaggg 100

 cttccttcct cggctccacc ctgtggatgt aatggcggcc cctgctctgt 150

 cctggcgtct gcccctcctc atcctcctcc tgcccctggc tacctcttgg 200

 gcatctgcag cggtgaatgg cacttcccag ttcacatgct tctacaactc 250

 gagagccaac atctcctgtg tctggagcca agatggggct ctgcaggaca 300

 cttcctgcca agtccatgcc tggccggaca gacggcggtg gaaccaaacc 350

 tgtgagctgc tccccgtgag tcaagcatcc tgggcctgca acctgatcct 400

 cggagcccca gattctcaga aactgaccac agttgacatc gtcaccctga 450

 gggtgctgtg ccgtgagggg gtgcgatgga gggtgatggc catccaggac 500

 ttcaagccct ttgagaacct tcgcctgatg gcccccatct ccctccaagt 550

 tgtccacgtg gagacccaca gatgcaacat aagctgggaa atctcccaag 600

 cctcccacta ctttgaaaga cacctggagt tcgaggcccg gacgctgtcc 650

 ccaggccaca cctgggagga ggcccccctg ctgactctca agcagaagca 700

 ggaatggatc tgcctggaga cgctcacccc agacacccag tatgagtttc 750

 aggtgcgggt caagcctctg caaggcgagt tcacgacctg gagcccctgg 800

 agccagcccc tggccttcag gacaaagcct gcagcccttg ggaaggacac 850

 cattccgtgg ctcggccacc tcctcgtggg cctcagcggg gcttttggct 900

 tcatcatctt agtgtacttg ctgatcaact gcaggaacac cgggccatgg 950

 ctgaagaagg tcctgaagtg taacacccca gacccctcga agttcttttc 1000

 ccagctgagc tcagagcatg gaggagacgt ccagaagtgg ctctcttcgc 1050

 ccttcccctc atcgtccttc agccctggcg gcctggcacc tgagatctcg 1100

 ccactagaag tgctggagag ggacaaggtg acgcagctgc tcctgcagca 1150

 ggacaaggtg cctgagcccg catccttaag cagcaaccac tcgctgacca 1200

 gctgcttcac caaccagggt tacttcttct tccacctccc ggatgccttg 1250

 gagatagagg cctgccaggt gtactttact tacgacccct actcagagga 1300

 agaccctgat gagggtgtgg ccggggcacc cacagggtct tccccccaac 1350

 ccctgcagcc tctgtcaggg gaggacgacg cctactgcac cttcccctcc 1400

 agggatgacc tgctgctctt ctcccccagt ctcctcggtg gccccagccc 1450

 cccaagcact gcccctgggg gcagtggggc cggtgaagag aggatgcccc 1500

 cttctttgca agaaagagtc cccagagact gggaccccca gcccctgggg 1550

 cctcccaccc caggagtccc agacctggtg gattttcagc caccccctga 1600

 gctggtgctg cgagaggctg gggaggaggt ccctgacgct ggccccaggg 1650

 agggagtcag tttcccctgg tccaggcctc ctgggcaggg ggagttcagg 1700

 gcccttaatg ctcgcctgcc cctgaacact gatgcctact tgtccctcca 1750

 agaactccag ggtcaggacc caactcactt ggtgtagaca gatggccagg 1800

 gtgggaggca ggcagctgcc tgctctgcgc cgagcctcag aaggaccctg 1850

 ttgagggtcc tcagtccact gctgaggaca ctcagtgtcc agttgcagct 1900

 ggacttctcc acccggatgg cccccaccca gtcctgcaca cttggtccat 1950

 ccatttccaa acctccactg ctgctcccgg gtcctgctgc ccgagccagg 2000

 aactgtgtgt gttgcagggg ggcagtaact ccccaactcc ctcgttaatc 2050

 acaggatccc acgaatttag gctcagaagc atcgctcctc tccagccctg 2100

 cagctattca ccaatatcag tcctcgcggc tctccagggc tccctgccct 2150

 gacctcttcc ctgggttttc tgccccagcc tcctccttcc ctcccctccc 2200

 cgtccacagg gcagcctgag cgtgctttcc aaaacccaaa tatggccacg 2250

 ctccccctcg gttcaaaacc ttgcacaggt cccactgccc tcagccccac 2300

 ttctcagcct ggtacttgta cctccggtgt cgtgtgggga catccccttc 2350

 tgcaatcctc cctaccgtcc tcctgagcca ctcagagctc cctcacaccc 2400

 cctctgttgc acatgctatt ccctggggct gctgtgcgct ccccctcatc 2450

 taggtgacaa acttccctga ctcttcaagt gccggttttg cttctcctgg 2500

 agggaagcac tgcctccctt aatctgccag aaacttctag cgtcagtgct 2550

 ggagggagaa gctgtcaggg acccagggcg cctggagaaa gaggccctgt 2600

 tactattcct ttgggatctc tgaggcctca gagtgcttgg ctgctgtatc 2650

 tttaatgctg gggcccaagt aagggcacag atccccccac aaagtggatg 2700

 cctgctgcat cttcccacag tggcttcaca gacccacaag agaagctgat 2750

 ggggagtaaa ccctggagtc cgaggcccag gcagcagccc cgcctagtgg 2800

 tgggccctga tgctgccagg cctgggacct cccactgccc cctccactgg 2850

 aggggtctcc tctgcagctc agggactggc acactggcct ccagaagggc 2900

 agctccacag ggcagggcct cattattttt cactgcccca gacacagtgc 2950

 ccaacacccc gtcgtatacc ctggatgaac gaattaatta cctggcacca 3000

 cctcgtctgg gctccctgcg cctgacattc acacagagag gcagagtccc 3050

 gtgcccatta ggtctggcat gccccctcct gcaaggggct caacccccta 3100

 ccccgacccc tccacgtatc tttcctaggc agatcacgtt gcaatggctc 3150

 aaacaacatt ccaccccagc aggacagtga ccccagtccc agctaactct 3200

 gacctgggag ccctcaggca cctgcactta caggccttgc tcacagctga 3250

 ttgggcacct gaccacacgc ccccacaggc tctgaccagc agcctatgag 3300

 ggggtttggc accaagctct gtccaatcag gtaggctggg cctgaactag 3350

 ccaatcagat caactctgtc ttgggcgttt gaactcaggg agggaggccc 3400

 ttgggagcag gtgcttgtgg acaaggctcc acaagcgttg agccttggaa 3450

 aggtagacaa gcgttgagcc actaagcaga ggaccttggg ttcccaatac 3500

 aaaaatacct actgctgaga gggctgctga ccatttggtc aggattcctg 3550

 ttgcctttat atccaaaata aactcccctt tcttgaggtt gtctgagtct 3600

 tgggtctatg ccttgaaaaa agctgaatta ttggacagtc tcacctcctg 3650

 ccatagggtc ctgaatgttt cagaccacaa ggggctccac acctttgctg 3700

 tgtgttctgg ggcaacctac taatcctctc tgcaagtcgg tctccttatc 3750

 cccccaaatg gaaattgtat ttgccttctc cactttggga ggctcccact 3800

 tcttgggagg gttacatttt ttaagtctta atcatttgtg acatatgtat 3850

 ctatacatcc gtatctttta atgatccgtg tgtaccatct ttgtgattat 3900

 ttccttaata ttttttcttt aagtcagttc attttcgttg aaatacattt 3950

 atttaaagaa aaatctttgt tactctgtaa atgaaaaaac ccattttcgc 4000

 tataaataaa aggtaactgt acaaaataag tacaatgcaa caaaa 4045

<210> 5338
<211> 551
<212> PRT
<213> Homo sapien

<400> 5338
 Met Ala Ala Pro Ala Leu Ser Trp Arg Leu Pro Leu Leu Ile Leu
   1               5                  10                  15

 Leu Leu Pro Leu Ala Thr Ser Trp Ala Ser Ala Ala Val Asn Gly
                  20                  25                  30

 Thr Ser Gln Phe Thr Cys Phe Tyr Asn Ser Arg Ala Asn Ile Ser
                  35                  40                  45

 Cys Val Trp Ser Gln Asp Gly Ala Leu Gln Asp Thr Ser Cys Gln
                  50                  55                  60

 Val His Ala Trp Pro Asp Arg Arg Arg Trp Asn Gln Thr Cys Glu
                  65                  70                  75

 Leu Leu Pro Val Ser Gln Ala Ser Trp Ala Cys Asn Leu Ile Leu
                  80                  85                  90

 Gly Ala Pro Asp Ser Gln Lys Leu Thr Thr Val Asp Ile Val Thr
                  95                 100                 105

 Leu Arg Val Leu Cys Arg Glu Gly Val Arg Trp Arg Val Met Ala
                 110                 115                 120

 Ile Gln Asp Phe Lys Pro Phe Glu Asn Leu Arg Leu Met Ala Pro
                 125                 130                 135

 Ile Ser Leu Gln Val Val His Val Glu Thr His Arg Cys Asn Ile
                 140                 145                 150

 Ser Trp Glu Ile Ser Gln Ala Ser His Tyr Phe Glu Arg His Leu
                 155                 160                 165

 Glu Phe Glu Ala Arg Thr Leu Ser Pro Gly His Thr Trp Glu Glu
                 170                 175                 180

 Ala Pro Leu Leu Thr Leu Lys Gln Lys Gln Glu Trp Ile Cys Leu
                 185                 190                 195

 Glu Thr Leu Thr Pro Asp Thr Gln Tyr Glu Phe Gln Val Arg Val
                 200                 205                 210

 Lys Pro Leu Gln Gly Glu Phe Thr Thr Trp Ser Pro Trp Ser Gln
                 215                 220                 225

 Pro Leu Ala Phe Arg Thr Lys Pro Ala Ala Leu Gly Lys Asp Thr
                 230                 235                 240

 Ile Pro Trp Leu Gly His Leu Leu Val Gly Leu Ser Gly Ala Phe
                 245                 250                 255

 Gly Phe Ile Ile Leu Val Tyr Leu Leu Ile Asn Cys Arg Asn Thr
                 260                 265                 270

 Gly Pro Trp Leu Lys Lys Val Leu Lys Cys Asn Thr Pro Asp Pro
                 275                 280                 285

 Ser Lys Phe Phe Ser Gln Leu Ser Ser Glu His Gly Gly Asp Val
                 290                 295                 300

 Gln Lys Trp Leu Ser Ser Pro Phe Pro Ser Ser Ser Phe Ser Pro
                 305                 310                 315

 Gly Gly Leu Ala Pro Glu Ile Ser Pro Leu Glu Val Leu Glu Arg
                 320                 325                 330

 Asp Lys Val Thr Gln Leu Leu Leu Gln Gln Asp Lys Val Pro Glu
                 335                 340                 345

 Pro Ala Ser Leu Ser Ser Asn His Ser Leu Thr Ser Cys Phe Thr
                 350                 355                 360

 Asn Gln Gly Tyr Phe Phe Phe His Leu Pro Asp Ala Leu Glu Ile
                 365                 370                 375

 Glu Ala Cys Gln Val Tyr Phe Thr Tyr Asp Pro Tyr Ser Glu Glu
                 380                 385                 390

 Asp Pro Asp Glu Gly Val Ala Gly Ala Pro Thr Gly Ser Ser Pro
                 395                 400                 405

 Gln Pro Leu Gln Pro Leu Ser Gly Glu Asp Asp Ala Tyr Cys Thr
                 410                 415                 420

 Phe Pro Ser Arg Asp Asp Leu Leu Leu Phe Ser Pro Ser Leu Leu
                 425                 430                 435

 Gly Gly Pro Ser Pro Pro Ser Thr Ala Pro Gly Gly Ser Gly Ala
                 440                 445                 450

 Gly Glu Glu Arg Met Pro Pro Ser Leu Gln Glu Arg Val Pro Arg
                 455                 460                 465

 Asp Trp Asp Pro Gln Pro Leu Gly Pro Pro Thr Pro Gly Val Pro
                 470                 475                 480

 Asp Leu Val Asp Phe Gln Pro Pro Pro Glu Leu Val Leu Arg Glu
                 485                 490                 495

 Ala Gly Glu Glu Val Pro Asp Ala Gly Pro Arg Glu Gly Val Ser
                 500                 505                 510

 Phe Pro Trp Ser Arg Pro Pro Gly Gln Gly Glu Phe Arg Ala Leu
                 515                 520                 525

 Asn Ala Arg Leu Pro Leu Asn Thr Asp Ala Tyr Leu Ser Leu Gln
                 530                 535                 540

 Glu Leu Gln Gly Gln Asp Pro Thr His Leu Val
                 545                 550

<210> 5339
<211> 816
<212> DNA
<213> Homo sapien

<400> 5339
 atgcactttc tttgccaaag gcaaacgcag aacgtttcag agccatgagg 50

 atgcttctgc atttgagttt gctagctctt ggagctgcct acgtgtatgc 100

 catccccaca gaaattccca caagtgcatt ggtgaaagag accttggcac 150

 tgctttctac tcatcgaact ctgctgatag ccaatgagac tctgaggatt 200

 cctgttcctg tacataaaaa tcaccaactg tgcactgaag aaatctttca 250

 gggaataggc acactggaga gtcaaactgt gcaagggggt actgtggaaa 300

 gactattcaa aaacttgtcc ttaataaaga aatacattga cggccaaaaa 350

 aaaaagtgtg gagaagaaag acggagagta aaccaattcc tagactacct 400

 gcaagagttt cttggtgtaa tgaacaccga gtggataata gaaagttgag 450

 actaaactgg tttgttgcag ccaaagattt tggaggagaa ggacatttta 500

 ctgcagtgag aatgagggcc aagaaagagt caggccttaa ttttcagtat 550

 aatttaactt cagagggaaa gtaaatattt caggcatact gacactttgc 600

 cagaaagcat aaaattctta aaatatattt cagatatcag aatcattgaa 650

 gtattttcct ccaggcaaaa ttgatatact tttttcttat ttaacttaac 700

 attctgtaaa atgtctgtta acttaatagt atttatgaaa tggttaagaa 750

 tttggtaaat tagtatttat ttaatgttat gttgtgttct aataaaacaa 800

 aaatagacaa ctgttc 816

<210> 5340
<211> 134
<212> PRT
<213> Homo sapien

<400> 5340
 Met Arg Met Leu Leu His Leu Ser Leu Leu Ala Leu Gly Ala Ala
   1               5                  10                  15

 Tyr Val Tyr Ala Ile Pro Thr Glu Ile Pro Thr Ser Ala Leu Val
                  20                  25                  30

 Lys Glu Thr Leu Ala Leu Leu Ser Thr His Arg Thr Leu Leu Ile
                  35                  40                  45

 Ala Asn Glu Thr Leu Arg Ile Pro Val Pro Val His Lys Asn His
                  50                  55                  60

 Gln Leu Cys Thr Glu Glu Ile Phe Gln Gly Ile Gly Thr Leu Glu
                  65                  70                  75

 Ser Gln Thr Val Gln Gly Gly Thr Val Glu Arg Leu Phe Lys Asn
                  80                  85                  90

 Leu Ser Leu Ile Lys Lys Tyr Ile Asp Gly Gln Lys Lys Lys Cys
                  95                 100                 105

 Gly Glu Glu Arg Arg Arg Val Asn Gln Phe Leu Asp Tyr Leu Gln
                 110                 115                 120

 Glu Phe Leu Gly Val Met Asn Thr Glu Trp Ile Ile Glu Ser
                 125                 130

<210> 5341
<211> 4932
<212> DNA
<213> Homo sapien

<400> 5341
 ggcagggcac acctggattg cattagaatg agactcacta cccagttcag 50

 gtgtgttgcg ttgtgggtct ccggcacatt tcagaggctg attaggaccc 100

 tgaccccaca ctggggttta cacccctaaa agcaggtgtg tcccgtggca 150

 actgagtggg tgcgtgaaaa ggggggatca tcaattacca gctggagcaa 200

 tcgaatcggt taaatgtgaa tcaagtcaca gtgcttcctt aacccaacct 250

 ctctgttggg gtcagccaca gcctaaaccg cctgccgttc agcctgagag 300

 gctgctgcta gcctgctcac gcatgcagcc cgggctgcag aggaagtgtg 350

 gggaggaagg aagtgggtat agaagggtgc tgagatgtgg gtcttgaaga 400

 gaatagccat aacgtctttg tcactaaaat gttccccagg ggccttcggc 450

 gagtcttttt gtttggtttt ttgtttttaa tctgtggctc ttgataattt 500

 atctagtggt tgcctacacc tgaaaaacaa gacacagtgt ttaactatca 550

 acgaaagaac tggacggctc cccgccgcag tcccactccc cgagtttgtg 600

 gctggcattt gggccacgcc gggctgggcg gctcacagcg aggggcgcgc 650

 agtttggggt cacacagctc cgcttctagg ccccaaccac cgttaaaagg 700

 ggaagcccgt gccccatcag gtccgctctt gctgagccca gagccatccc 750

 gcgctctgcg ggctgggagg cccgggccag acgcgagtcc tgcgcagccg 800

 aggttcccca gcgccccctg cagccgcgcg taggcagaga cggagcccgg 850

 ccctgcgcct ccgcaccacg cccgggaccc cacccagcgg cccgtacccg 900

 gagaagcagc gcgagcaccc gaagctcccg gctcggcggc agaaaccggg 950

 agtggggccg ggcgagtgcg cggcatccca ggccggcccg aacgtccgcc 1000

 cgcggtgggc cgacttcccc tcctcttccc tctctccttc ctttagcccg 1050

 ctggcgccgg acacgctgcg cctcatctct tggggcgttc ttccccgttg 1100

 gccaaccgtc gcatcccgtg caactttggg gtagtggccg cttagtgttg 1150

 aatgttcccc accgagagcg catggcttgg gaagcgaggc gcgaacccgg 1200

 gccccgaagc cgccgtccgg gagacggtga tgctgttgct gtgcctgggg 1250

 gtcccgaccg gccgccccta caacgtggac actgagagcg cgctgcttta 1300

 ccagggcccc cacaacacgc tgttcggcta ctcggtcgtg ctgcacagcc 1350

 acggggcgaa ccgatggctc ctagtgggtg cgcccactgc caactggctc 1400

 gccaacgctt cagtgatcaa tcccggggcg atttacagat gcaggatcgg 1450

 aaagaatccc ggccagacgt gcgaacagct ccagctgggt agccctaatg 1500

 gagaaccttg tggaaagact tgtttggaag agagagacaa tcagtggttg 1550

 ggggtcacac tttccagaca gccaggagaa aatggatcca tcgtgacttg 1600

 tgggcataga tggaaaaata tattttacat aaagaatgaa aataagctcc 1650

 ccactggtgg ttgctatgga gtgccccctg atttacgaac agaactgagt 1700

 aaaagaatag ctccgtgtta tcaagattat gtgaaaaaat ttggagaaaa 1750

 ttttgcatca tgtcaagctg gaatatccag tttttacaca aaggatttaa 1800

 ttgtgatggg ggccccagga tcatcttact ggactggctc tctttttgtc 1850

 tacaatataa ctacaaataa atacaaggct tttttagaca aacaaaatca 1900

 agtaaaattt ggaagttatt taggatattc agtcggagct ggtcattttc 1950

 ggagccagca tactaccgaa gtagtcggag gagctcctca acatgagcag 2000

 attggtaagg catatatatt cagcattgat gaaaaagaac taaatatctt 2050

 acatgaaatg aaaggtaaaa agcttggatc gtactttgga gcttctgtct 2100

 gtgctgtgga cctcaatgca gatggcttct cagatctgct cgtgggagca 2150

 cccatgcaga gcaccatcag agaggaagga agagtgtttg tgtacatcaa 2200

 ctctggctcg ggagcagtaa tgaatgcaat ggaaacaaac ctcgttggaa 2250

 gtgacaaata tgctgcaaga tttggggaat ctatagttaa tcttggcgac 2300

 attgacaatg atggctttga agatgttgct atcggagctc cacaagaaga 2350

 tgacttgcaa ggtgctattt atatttacaa tggccgtgca gatgggatct 2400

 cgtcaacctt ctcacagaga attgaaggac ttcagatcag caaatcgtta 2450

 agtatgtttg gacagtctat atcaggacaa attgatgcag ataataatgg 2500

 ctatgtagat gtagcagttg gtgcttttcg gtctgattct gctgtcttgc 2550

 taaggacaag acctgtagta attgttgacg cttctttaag ccaccctgag 2600

 tcagtaaata gaacgaaatt tgactgtgtt gaaaatggat ggccttctgt 2650

 gtgcatagat ctaacacttt gtttctcata taagggcaag gaagttccag 2700

 gttacattgt tttgttttat aacatgagtt tggatgtgaa cagaaaggca 2750

 gagtctccac caagattcta tttctcttct aatggaactt ctgacgtgat 2800

 tacaggaagc atacaggtgt ccagcagaga agctaactgt agaacacatc 2850

 aagcatttat gcggaaagat gtgcgggaca tcctcacccc aattcagatt 2900

 gaagctgctt accaccttgg tcctcatgtc atcagtaaac gaagtacaga 2950

 ggaattccca ccacttcagc caattcttca gcagaagaaa gaaaaagaca 3000

 taatgaaaaa aacaataaac tttgcaaggt tttgtgccca tgaaaattgt 3050

 tctgctgatt tacaggtttc tgcaaagatt gggtttttga agccccatga 3100

 aaataaaaca tatcttgctg ttgggagtat gaagacattg atgttgaatg 3150

 tgtccttgtt taatgctgga gatgatgcat atgaaacgac tctacatgtc 3200

 aaactacccg tgggtcttta tttcattaag attttagagc tggaagagaa 3250

 gcaaataaac tgtgaagtca cagataactc tggcgtggta caacttgact 3300

 gcagtattgg ctatatatat gtagatcatc tctcaaggat agatattagc 3350

 tttctcctgg atgtgagctc actcagcaga gcggaagagg acctcagtat 3400

 cacagtgcat gctacctgtg aaaatgaaga ggaaatggac aatctaaagc 3450

 acagcagagt gactgtagca atacctttaa aatatgaggt taagctgact 3500

 gttcatgggt ttgtaaaccc aacttcattt gtgtatggat caaatgatga 3550

 aaatgagcct gaaacgtgca tggtggagaa aatgaactta actttccatg 3600

 ttatcaacac tggcaatagt atggctccca atgttagtgt ggaaataatg 3650

 gtaccaaatt cttttagccc ccaaactgat aagctgttca acattttgga 3700

 tgtccagact actactggag aatgccactt tgaaaattat caaagagtgt 3750

 gtgcattaga gcagcaaaag agtgcaatgc agaccttgaa aggcatagtc 3800

 cggttcttgt ccaagactga taagaggcta ttgtactgca taaaagctga 3850

 tccacattgt ttaaatttct tgtgtaattt tgggaaaatg gaaagtggaa 3900

 aagaagccag tgttcatatc caactggaag gccggccatc cattttagaa 3950

 atggatgaga cttcagcact caagtttgaa ataagagcaa caggttttcc 4000

 agagccaaat ccaagagtaa ttgaactaaa caaggatgag aatgttgcgc 4050

 atgttctact ggaaggacta catcatcaaa gacccaaacg ttatttcacc 4100

 atagtgatta tttcaagtag cttgctactt ggacttattg tacttctgtt 4150

 gatctcatat gttatgtgga aggctggctt ctttaaaaga caatacaaat 4200

 ctatcctaca agaagaaaac agaagagaca gttggagtta tatcaacagt 4250

 aaaagcaatg atgattaagg acttctttca aattgagaga atggaaaaca 4300

 gactcaggtt gtagtaaaga aatttaaaag acactgttta caagaaaaaa 4350

 tgaattttgt ttggacttct tttactcatg atcttgtgac atattatgtc 4400

 ttcatgcaag gggaaaatct cagcaatgat tactctttga gatagaagaa 4450

 ctgcaaaggt aataatacag ccaaagataa tctctcagct tttaaatggg 4500

 tagagaaaca ctaaagcatt caatttattc aagaaaagta agcccttgaa 4550

 gatatcttga aatgaaagta taactgagtt aaattatact ggagaagtct 4600

 tagacttgaa atactactta ccatatgtgc ttgcctcagt aaaatgaacc 4650

 ccactgggtg ggcagaggtt catttcaaat acatctttga tacttgttca 4700

 aaatatgttc tttaaaaata taatttttta gagagctgtt cccaaatttt 4750

 ctaacgagtg gaccattatc actttaaagc cctttattta taatacattt 4800

 cctacgggct gtgttccaac aaccattttt tttcagcaga ctatgaatat 4850

 tatagtatta taggccaaac tggcaaactt cagactgaac atgtacactg 4900

 gtttgagctt agtgaaatga cttccggaat ct 4932

<210> 5342
<211> 1038
<212> PRT
<213> Homo sapien

<400> 5342
 Met Phe Pro Thr Glu Ser Ala Trp Leu Gly Lys Arg Gly Ala Asn
   1               5                  10                  15

 Pro Gly Pro Glu Ala Ala Val Arg Glu Thr Val Met Leu Leu Leu
                  20                  25                  30

 Cys Leu Gly Val Pro Thr Gly Arg Pro Tyr Asn Val Asp Thr Glu
                  35                  40                  45

 Ser Ala Leu Leu Tyr Gln Gly Pro His Asn Thr Leu Phe Gly Tyr
                  50                  55                  60

 Ser Val Val Leu His Ser His Gly Ala Asn Arg Trp Leu Leu Val
                  65                  70                  75

 Gly Ala Pro Thr Ala Asn Trp Leu Ala Asn Ala Ser Val Ile Asn
                  80                  85                  90

 Pro Gly Ala Ile Tyr Arg Cys Arg Ile Gly Lys Asn Pro Gly Gln
                  95                 100                 105

 Thr Cys Glu Gln Leu Gln Leu Gly Ser Pro Asn Gly Glu Pro Cys
                 110                 115                 120

 Gly Lys Thr Cys Leu Glu Glu Arg Asp Asn Gln Trp Leu Gly Val
                 125                 130                 135

 Thr Leu Ser Arg Gln Pro Gly Glu Asn Gly Ser Ile Val Thr Cys
                 140                 145                 150

 Gly His Arg Trp Lys Asn Ile Phe Tyr Ile Lys Asn Glu Asn Lys
                 155                 160                 165

 Leu Pro Thr Gly Gly Cys Tyr Gly Val Pro Pro Asp Leu Arg Thr
                 170                 175                 180

 Glu Leu Ser Lys Arg Ile Ala Pro Cys Tyr Gln Asp Tyr Val Lys
                 185                 190                 195

 Lys Phe Gly Glu Asn Phe Ala Ser Cys Gln Ala Gly Ile Ser Ser
                 200                 205                 210

 Phe Tyr Thr Lys Asp Leu Ile Val Met Gly Ala Pro Gly Ser Ser
                 215                 220                 225

 Tyr Trp Thr Gly Ser Leu Phe Val Tyr Asn Ile Thr Thr Asn Lys
                 230                 235                 240

 Tyr Lys Ala Phe Leu Asp Lys Gln Asn Gln Val Lys Phe Gly Ser
                 245                 250                 255

 Tyr Leu Gly Tyr Ser Val Gly Ala Gly His Phe Arg Ser Gln His
                 260                 265                 270

 Thr Thr Glu Val Val Gly Gly Ala Pro Gln His Glu Gln Ile Gly
                 275                 280                 285

 Lys Ala Tyr Ile Phe Ser Ile Asp Glu Lys Glu Leu Asn Ile Leu
                 290                 295                 300

 His Glu Met Lys Gly Lys Lys Leu Gly Ser Tyr Phe Gly Ala Ser
                 305                 310                 315

 Val Cys Ala Val Asp Leu Asn Ala Asp Gly Phe Ser Asp Leu Leu
                 320                 325                 330

 Val Gly Ala Pro Met Gln Ser Thr Ile Arg Glu Glu Gly Arg Val
                 335                 340                 345

 Phe Val Tyr Ile Asn Ser Gly Ser Gly Ala Val Met Asn Ala Met
                 350                 355                 360

 Glu Thr Asn Leu Val Gly Ser Asp Lys Tyr Ala Ala Arg Phe Gly
                 365                 370                 375

 Glu Ser Ile Val Asn Leu Gly Asp Ile Asp Asn Asp Gly Phe Glu
                 380                 385                 390

 Asp Val Ala Ile Gly Ala Pro Gln Glu Asp Asp Leu Gln Gly Ala
                 395                 400                 405

 Ile Tyr Ile Tyr Asn Gly Arg Ala Asp Gly Ile Ser Ser Thr Phe
                 410                 415                 420

 Ser Gln Arg Ile Glu Gly Leu Gln Ile Ser Lys Ser Leu Ser Met
                 425                 430                 435

 Phe Gly Gln Ser Ile Ser Gly Gln Ile Asp Ala Asp Asn Asn Gly
                 440                 445                 450

 Tyr Val Asp Val Ala Val Gly Ala Phe Arg Ser Asp Ser Ala Val
                 455                 460                 465

 Leu Leu Arg Thr Arg Pro Val Val Ile Val Asp Ala Ser Leu Ser
                 470                 475                 480

 His Pro Glu Ser Val Asn Arg Thr Lys Phe Asp Cys Val Glu Asn
                 485                 490                 495

 Gly Trp Pro Ser Val Cys Ile Asp Leu Thr Leu Cys Phe Ser Tyr
                 500                 505                 510

 Lys Gly Lys Glu Val Pro Gly Tyr Ile Val Leu Phe Tyr Asn Met
                 515                 520                 525

 Ser Leu Asp Val Asn Arg Lys Ala Glu Ser Pro Pro Arg Phe Tyr
                 530                 535                 540

 Phe Ser Ser Asn Gly Thr Ser Asp Val Ile Thr Gly Ser Ile Gln
                 545                 550                 555

 Val Ser Ser Arg Glu Ala Asn Cys Arg Thr His Gln Ala Phe Met
                 560                 565                 570

 Arg Lys Asp Val Arg Asp Ile Leu Thr Pro Ile Gln Ile Glu Ala
                 575                 580                 585

 Ala Tyr His Leu Gly Pro His Val Ile Ser Lys Arg Ser Thr Glu
                 590                 595                 600

 Glu Phe Pro Pro Leu Gln Pro Ile Leu Gln Gln Lys Lys Glu Lys
                 605                 610                 615

 Asp Ile Met Lys Lys Thr Ile Asn Phe Ala Arg Phe Cys Ala His
                 620                 625                 630

 Glu Asn Cys Ser Ala Asp Leu Gln Val Ser Ala Lys Ile Gly Phe
                 635                 640                 645

 Leu Lys Pro His Glu Asn Lys Thr Tyr Leu Ala Val Gly Ser Met
                 650                 655                 660

 Lys Thr Leu Met Leu Asn Val Ser Leu Phe Asn Ala Gly Asp Asp
                 665                 670                 675

 Ala Tyr Glu Thr Thr Leu His Val Lys Leu Pro Val Gly Leu Tyr
                 680                 685                 690

 Phe Ile Lys Ile Leu Glu Leu Glu Glu Lys Gln Ile Asn Cys Glu
                 695                 700                 705

 Val Thr Asp Asn Ser Gly Val Val Gln Leu Asp Cys Ser Ile Gly
                 710                 715                 720

 Tyr Ile Tyr Val Asp His Leu Ser Arg Ile Asp Ile Ser Phe Leu
                 725                 730                 735

 Leu Asp Val Ser Ser Leu Ser Arg Ala Glu Glu Asp Leu Ser Ile
                 740                 745                 750

 Thr Val His Ala Thr Cys Glu Asn Glu Glu Glu Met Asp Asn Leu
                 755                 760                 765

 Lys His Ser Arg Val Thr Val Ala Ile Pro Leu Lys Tyr Glu Val
                 770                 775                 780

 Lys Leu Thr Val His Gly Phe Val Asn Pro Thr Ser Phe Val Tyr
                 785                 790                 795

 Gly Ser Asn Asp Glu Asn Glu Pro Glu Thr Cys Met Val Glu Lys
                 800                 805                 810

 Met Asn Leu Thr Phe His Val Ile Asn Thr Gly Asn Ser Met Ala
                 815                 820                 825

 Pro Asn Val Ser Val Glu Ile Met Val Pro Asn Ser Phe Ser Pro
                 830                 835                 840

 Gln Thr Asp Lys Leu Phe Asn Ile Leu Asp Val Gln Thr Thr Thr
                 845                 850                 855

 Gly Glu Cys His Phe Glu Asn Tyr Gln Arg Val Cys Ala Leu Glu
                 860                 865                 870

 Gln Gln Lys Ser Ala Met Gln Thr Leu Lys Gly Ile Val Arg Phe
                 875                 880                 885

 Leu Ser Lys Thr Asp Lys Arg Leu Leu Tyr Cys Ile Lys Ala Asp
                 890                 895                 900

 Pro His Cys Leu Asn Phe Leu Cys Asn Phe Gly Lys Met Glu Ser
                 905                 910                 915

 Gly Lys Glu Ala Ser Val His Ile Gln Leu Glu Gly Arg Pro Ser
                 920                 925                 930

 Ile Leu Glu Met Asp Glu Thr Ser Ala Leu Lys Phe Glu Ile Arg
                 935                 940                 945

 Ala Thr Gly Phe Pro Glu Pro Asn Pro Arg Val Ile Glu Leu Asn
                 950                 955                 960

 Lys Asp Glu Asn Val Ala His Val Leu Leu Glu Gly Leu His His
                 965                 970                 975

 Gln Arg Pro Lys Arg Tyr Phe Thr Ile Val Ile Ile Ser Ser Ser
                 980                 985                 990

 Leu Leu Leu Gly Leu Ile Val Leu Leu Leu Ile Ser Tyr Val Met
                 995                1000                1005

 Trp Lys Ala Gly Phe Phe Lys Arg Gln Tyr Lys Ser Ile Leu Gln
                1010                1015                1020

 Glu Glu Asn Arg Arg Asp Ser Trp Ser Tyr Ile Asn Ser Lys Ser
                1025                1030                1035

 Asn Asp Asp


<210> 5343
<211> 2798
<212> DNA
<213> Homo sapien

<400> 5343
 cgttgctgtc gctctgcacg cacctatgtg gaaactaaag cccagagaga 50

 aagtctgact tgccccacag ccagtgagtg actgcagcag caccagaatc 100

 tggtctgttt cctgtttggc tcttctacca ctacggcttg ggatctcggg 150

 catggtggct ttgccaatgg tccttgtttt gctgctggtc ctgagcagag 200

 gtgagagtga attggacgcc aagatcccat ccacagggga tgccacagaa 250

 tggcggaatc ctcacctgtc catgctgggg tcctgccagc cagccccctc 300

 ctgccagaag tgcatcctct cacaccccag ctgtgcatgg tgcaagcaac 350

 tgaacttcac cgcgtcggga gaggcggagg cgcggcgctg cgcccgacga 400

 gaggagctgc tggctcgagg ctgcccgctg gaggagctgg aggagccccg 450

 cggccagcag gaggtgctgc aggaccagcc gctcagccag ggcgcccgcg 500

 gagagggtgc cacccagctg gcgccgcagc gggtccgggt cacgctgcgg 550

 cctggggagc cccagcagct ccaggtccgc ttccttcgtg ctgagggata 600

 cccggtggac ctgtactacc ttatggacct gagctactcc atgaaggacg 650

 acctggaacg cgtgcgccag ctcgggcacg ctctgctggt ccggctgcag 700

 gaagtcaccc attctgtgcg cattggtttt ggttcctttg tggacaaaac 750

 ggtgctgccc tttgtgagca cagtaccctc caaactgcgc cacccctgcc 800

 ccacccggct ggagcgctgc cagtcaccat tcagctttca ccatgtgctg 850

 tccctgacgg gggacgcaca agccttcgag cgggaggtgg ggcgccagag 900

 tgtgtccggc aatctggact cgcctgaagg tggcttcgat gccattctgc 950

 aggctgcact ctgccaggag cagattggct ggagaaatgt gtcccggctg 1000

 ctggtgttca cttcagacga cacattccat acagctgggg acgggaagtt 1050

 gggcggcatt ttcatgccca gtgatgggca ctgccacttg gacagcaatg 1100

 gcctctacag tcgcagcaca gagtttgact acccttctgt gggtcaggta 1150

 gcccaggccc tctctgcagc aaatatccag cccatctttg ctgtcaccag 1200

 tgccgcactg cctgtctacc aggagctgag taaactgatt cctaagtctg 1250

 cagttgggga gctgagtgag gactccagca acgtggtaca gctcatcatg 1300

 gatgcttata atagcctgtc ttccaccgtg acccttgaac actcttcact 1350

 ccctcctggg gtccacattt cttacgaatc ccagtgtgag ggtcctgaga 1400

 agagggaggg taaggctgag gatcgaggac agtgcaacca cgtccgaatc 1450

 aaccagacgg tgactttctg ggtttctctc caagccaccc actgcctccc 1500

 agagccccat ctcctgaggc tccgggccct tggcttctca gaggagctga 1550

 ttgtggagtt gcacacgctg tgtgactgta attgcagtga cacccagccc 1600

 caggctcccc actgcagtga tggccaggga cacctacaat gtggtgtatg 1650

 cagctgtgcc cctggccgcc taggtcggct ctgtgagtgc tctgtggcag 1700

 agctgtcctc cccagacctg gaatctgggt gccgggctcc caatggcaca 1750

 gggcccctgt gcagtggaaa gggtcactgt caatgtggac gctgcagctg 1800

 cagtggacag agctctgggc atctgtgcga gtgtgacgat gccagctgtg 1850

 agcgacatga gggcatcctc tgcggaggct ttggtcgctg ccaatgtgga 1900

 gtatgtcact gtcatgccaa ccgcacgggc agagcatgcg aatgcagtgg 1950

 ggacatggac agttgcatca gtcccgaggg agggctctgc agtgggcatg 2000

 gacgctgcaa atgcaaccgc tgccagtgct tggacggcta ctatggtgct 2050

 ctatgcgacc aatgcccagg ctgcaagaca ccatgcgaga gacaccggga 2100

 ctgtgcagag tgtggggcct tcaggactgg cccactggcc accaactgca 2150

 gtacagcttg tgcccatacc aatgtgaccc tggccttggc ccctatcttg 2200

 gatgatggct ggtgcaaaga gcggaccctg gacaaccagc tgttcttctt 2250

 cttggtggag gatgacgcca gaggcacggt cgtgctcaga gtgagacccc 2300

 aagaaaaggg agcagaccac acgcaggcca ttgtgctggg ctgcgtaggg 2350

 ggcatcgtgg cagtggggct ggggctggtc ctggcttacc ggctctcggt 2400

 ggaaatctat gaccgccggg aatacagtcg ctttgagaag gagcagcaac 2450

 aactcaactg gaagcaggac agtaatcctc tctacaaaag tgccatcacg 2500

 accaccatca atcctcgctt tcaagaggca gacagtccca ctctctgaag 2550

 gagggaggga cacttaccca aggctcttct ccttggagga cagtgggaac 2600

 tggagggtga gaggaagggt gggtctgtaa gaccttggta ggggactaat 2650

 tcactggcga ggtgcggcca ccaccctact tcattttcag agtgacaccc 2700

 aagagggctg cttcccatgc ctgcaacctt gcatccatct gggctacccc 2750

 acccaagtat acaataaagt cttacctcag aaaaaaaaaa aaaaaaaa 2798

<210> 5344
<211> 798
<212> PRT
<213> Homo sapien

<400> 5344
 Met Val Ala Leu Pro Met Val Leu Val Leu Leu Leu Val Leu Ser
   1               5                  10                  15

 Arg Gly Glu Ser Glu Leu Asp Ala Lys Ile Pro Ser Thr Gly Asp
                  20                  25                  30

 Ala Thr Glu Trp Arg Asn Pro His Leu Ser Met Leu Gly Ser Cys
                  35                  40                  45

 Gln Pro Ala Pro Ser Cys Gln Lys Cys Ile Leu Ser His Pro Ser
                  50                  55                  60

 Cys Ala Trp Cys Lys Gln Leu Asn Phe Thr Ala Ser Gly Glu Ala
                  65                  70                  75

 Glu Ala Arg Arg Cys Ala Arg Arg Glu Glu Leu Leu Ala Arg Gly
                  80                  85                  90

 Cys Pro Leu Glu Glu Leu Glu Glu Pro Arg Gly Gln Gln Glu Val
                  95                 100                 105

 Leu Gln Asp Gln Pro Leu Ser Gln Gly Ala Arg Gly Glu Gly Ala
                 110                 115                 120

 Thr Gln Leu Ala Pro Gln Arg Val Arg Val Thr Leu Arg Pro Gly
                 125                 130                 135

 Glu Pro Gln Gln Leu Gln Val Arg Phe Leu Arg Ala Glu Gly Tyr
                 140                 145                 150

 Pro Val Asp Leu Tyr Tyr Leu Met Asp Leu Ser Tyr Ser Met Lys
                 155                 160                 165

 Asp Asp Leu Glu Arg Val Arg Gln Leu Gly His Ala Leu Leu Val
                 170                 175                 180

 Arg Leu Gln Glu Val Thr His Ser Val Arg Ile Gly Phe Gly Ser
                 185                 190                 195

 Phe Val Asp Lys Thr Val Leu Pro Phe Val Ser Thr Val Pro Ser
                 200                 205                 210

 Lys Leu Arg His Pro Cys Pro Thr Arg Leu Glu Arg Cys Gln Ser
                 215                 220                 225

 Pro Phe Ser Phe His His Val Leu Ser Leu Thr Gly Asp Ala Gln
                 230                 235                 240

 Ala Phe Glu Arg Glu Val Gly Arg Gln Ser Val Ser Gly Asn Leu
                 245                 250                 255

 Asp Ser Pro Glu Gly Gly Phe Asp Ala Ile Leu Gln Ala Ala Leu
                 260                 265                 270

 Cys Gln Glu Gln Ile Gly Trp Arg Asn Val Ser Arg Leu Leu Val
                 275                 280                 285

 Phe Thr Ser Asp Asp Thr Phe His Thr Ala Gly Asp Gly Lys Leu
                 290                 295                 300

 Gly Gly Ile Phe Met Pro Ser Asp Gly His Cys His Leu Asp Ser
                 305                 310                 315

 Asn Gly Leu Tyr Ser Arg Ser Thr Glu Phe Asp Tyr Pro Ser Val
                 320                 325                 330

 Gly Gln Val Ala Gln Ala Leu Ser Ala Ala Asn Ile Gln Pro Ile
                 335                 340                 345

 Phe Ala Val Thr Ser Ala Ala Leu Pro Val Tyr Gln Glu Leu Ser
                 350                 355                 360

 Lys Leu Ile Pro Lys Ser Ala Val Gly Glu Leu Ser Glu Asp Ser
                 365                 370                 375

 Ser Asn Val Val Gln Leu Ile Met Asp Ala Tyr Asn Ser Leu Ser
                 380                 385                 390

 Ser Thr Val Thr Leu Glu His Ser Ser Leu Pro Pro Gly Val His
                 395                 400                 405

 Ile Ser Tyr Glu Ser Gln Cys Glu Gly Pro Glu Lys Arg Glu Gly
                 410                 415                 420

 Lys Ala Glu Asp Arg Gly Gln Cys Asn His Val Arg Ile Asn Gln
                 425                 430                 435

 Thr Val Thr Phe Trp Val Ser Leu Gln Ala Thr His Cys Leu Pro
                 440                 445                 450

 Glu Pro His Leu Leu Arg Leu Arg Ala Leu Gly Phe Ser Glu Glu
                 455                 460                 465

 Leu Ile Val Glu Leu His Thr Leu Cys Asp Cys Asn Cys Ser Asp
                 470                 475                 480

 Thr Gln Pro Gln Ala Pro His Cys Ser Asp Gly Gln Gly His Leu
                 485                 490                 495

 Gln Cys Gly Val Cys Ser Cys Ala Pro Gly Arg Leu Gly Arg Leu
                 500                 505                 510

 Cys Glu Cys Ser Val Ala Glu Leu Ser Ser Pro Asp Leu Glu Ser
                 515                 520                 525

 Gly Cys Arg Ala Pro Asn Gly Thr Gly Pro Leu Cys Ser Gly Lys
                 530                 535                 540

 Gly His Cys Gln Cys Gly Arg Cys Ser Cys Ser Gly Gln Ser Ser
                 545                 550                 555

 Gly His Leu Cys Glu Cys Asp Asp Ala Ser Cys Glu Arg His Glu
                 560                 565                 570

 Gly Ile Leu Cys Gly Gly Phe Gly Arg Cys Gln Cys Gly Val Cys
                 575                 580                 585

 His Cys His Ala Asn Arg Thr Gly Arg Ala Cys Glu Cys Ser Gly
                 590                 595                 600

 Asp Met Asp Ser Cys Ile Ser Pro Glu Gly Gly Leu Cys Ser Gly
                 605                 610                 615

 His Gly Arg Cys Lys Cys Asn Arg Cys Gln Cys Leu Asp Gly Tyr
                 620                 625                 630

 Tyr Gly Ala Leu Cys Asp Gln Cys Pro Gly Cys Lys Thr Pro Cys
                 635                 640                 645

 Glu Arg His Arg Asp Cys Ala Glu Cys Gly Ala Phe Arg Thr Gly
                 650                 655                 660

 Pro Leu Ala Thr Asn Cys Ser Thr Ala Cys Ala His Thr Asn Val
                 665                 670                 675

 Thr Leu Ala Leu Ala Pro Ile Leu Asp Asp Gly Trp Cys Lys Glu
                 680                 685                 690

 Arg Thr Leu Asp Asn Gln Leu Phe Phe Phe Leu Val Glu Asp Asp
                 695                 700                 705

 Ala Arg Gly Thr Val Val Leu Arg Val Arg Pro Gln Glu Lys Gly
                 710                 715                 720

 Ala Asp His Thr Gln Ala Ile Val Leu Gly Cys Val Gly Gly Ile
                 725                 730                 735

 Val Ala Val Gly Leu Gly Leu Val Leu Ala Tyr Arg Leu Ser Val
                 740                 745                 750

 Glu Ile Tyr Asp Arg Arg Glu Tyr Ser Arg Phe Glu Lys Glu Gln
                 755                 760                 765

 Gln Gln Leu Asn Trp Lys Gln Asp Ser Asn Pro Leu Tyr Lys Ser
                 770                 775                 780

 Ala Ile Thr Thr Thr Ile Asn Pro Arg Phe Gln Glu Ala Asp Ser
                 785                 790                 795

 Pro Thr Leu


<210> 5345
<211> 3699
<212> DNA
<213> Homo sapien

<400> 5345
 gttctgaatg atgactgacg cgggtttggg tgatacccct cacagcccct 50

 gtcattccgg agtcataagg cacccgcgcg tctagcccca gcgccagggc 100

 acgcgagcgg cgctggaggg aggaaagctt ccgcctgcgg gccggacaaa 150

 agtcccgcct gcccacggct ttttgcccgc cgctcgtgac cgagacgcct 200

 cgccgcggcc agctcgctgc tctcgctggc ggatggtgtg tggccgccgc 250

 aggacgcccg ccgtgcccgg gccatgaagt agcggctgct ggcggcgccg 300

 ctgcccaacc gccagcccca gccccgcgct gcgctgcccg gtcctctccc 350

 ggcggggtcg tatcggcgtg gacatggctg gccgcgtccc tagcctgcta 400

 gttctccttg tttttccaag cagctgtttg gctttccgaa gcccactttc 450

 tgtctttaag aggtttaaag aaactaccag accattttcc aatgaatgtc 500

 ttggtaccac cagacccgta gttcctattg attcatcaga ttttgcattg 550

 gatattcgca tgcctggggt tacacctaaa cagtccgata catacttctg 600

 catgtctatg cgaataccag tggatgagga agccttcgtg attgacttca 650

 agcctcgagc cagcatggat actgtccatc acatgttact ttttggatgc 700

 aatatgcctt catccactgg aagttactgg ttttgtgatg aaggaacctg 750

 tacagataaa gccaatattc tgtatgcctg ggcgagaaat gctcccccta 800

 cccggctccc caaaggtgtt ggattcagag ttggaggaga gactggaagt 850

 aaatactttg tactacaggt acactatggg gatattagtg cttttagaga 900

 taataacaag gactgttctg gtgtgtcctt acacctcaca cgtctgccac 950

 agcctttaat tgctggcatg taccttatga tgtctgttga cactgttatc 1000

 ccagcaggag aaaaagtggt gaattctgac atttcatgcc attataaaaa 1050

 ttatccaatg catgtctttg cctatagagt tcacactcac catttaggta 1100

 aggtagtaag tggatacaga gtaagaaatg gacagtggac actgattgga 1150

 cggcagagcc ctcagctgcc acaggctttc taccctgtgg ggcatccagt 1200

 tgatgtaagt tttggtgacc tactggctgc aagatgtgta ttcactggtg 1250

 aaggaaggac agaagccaca cacattggtg gcacgtctag tgatgaaatg 1300

 tgcaacttat acattatgta ttacatggaa gccaagcatg cagtttcttt 1350

 catgacctgt acccagaatg tagctccaga tatgttcaga accataccac 1400

 cagaggccaa cattccaatt cccgtgaagt ctgatatggt tatgatgcat 1450

 gaacatcata aagaaacaga atataaagat aagattcctt tactacagca 1500

 gccaaaacga gaagaagaag aagtgttaga ccagggtgat ttctattcac 1550

 tactttccaa gctgctagga gaaagggaag atgttgttca tgtgcacaaa 1600

 tataatccta cagaaaaggc agaatcagag tcagacctgg tagctgagat 1650

 tgcaaatgta gtccaaaaaa aggatcttgg tcgatctgat gccagagagg 1700

 gtgcagaaca tgagaggggt aatgctattc ttgtcagaga cagaattcac 1750

 aaattccaca gactagtatc taccttgagg ccaccagaga gcagagtttt 1800

 ctcattacag cagcccccac ctggtgaagg cacctgggaa ccagaacaca 1850

 caggagattt ccacatggaa gaggcactgg attggcctgg agtatacttg 1900

 ttaccaggcc aggtttctgg ggtggctcta gaccctaaga ataacctggt 1950

 gattttccac agaggtgacc atgtctggga tggaaactcg tttgacagca 2000

 agtttgttta ccagcaaata ggactcggac caattgaaga agacactatt 2050

 cttgtcatag atccaaataa tgctgcagta ctccagtcca gtggaaaaaa 2100

 tctgttttac ttgccacatg gcttgagtat agataaagat gggaattatt 2150

 gggtcacaga cgtggctctc catcaggtgt tcaaactgga tccaaacaat 2200

 aaagaaggcc ctgtattaat cctgggaagg agcatgcaac caggcagtga 2250

 ccagaatcac ttctgtcaac ccactgatgt ggctgtggat ccaggcactg 2300

 gagccattta tgtatcagat ggttactgca acagcaggat tgtgcagttt 2350

 tcaccaagtg gaaagttcat cacacagtgg ggagaagagt cttcagggag 2400

 cagtcctctg ccaggccagt tcactgttcc tcacagcttg gctcttgtgc 2450

 ctcttttggg ccaattatgt gtggcagacc gggaaaatgg tcggatccag 2500

 tgttttaaaa ctgacaccaa agaatttgtg agagagatta agcattcatc 2550

 atttggaaga aatgtatttg caatttcata tataccaggc ttgctctttg 2600

 cagtgaatgg gaagcctcat tttggggacc aagaacctgt acaaggattt 2650

 gtgatgaact tttccaatgg ggaaattata gacatcttca agccagtgcg 2700

 caagcacttt gatatgcctc atgatattgt tgcatctgaa gatgggactg 2750

 tgtacattgg agatgctcat accaacaccg tgtggaagtt caccttgact 2800

 gagaaattgg aacatcgatc agttaaaaag gctggcattg aggtccagga 2850

 aatcaaagga aagggaagtg gaggcttaaa ccttggtaat ttctttgcaa 2900

 gccgtaaggg ctacagtcga aaagggtttg accggcttag cactgagggc 2950

 agtgaccaag agaaagagga tgatggaagt gaatcagaag aggagtattc 3000

 agcacctctg cctgcgctcg caccttcctc ctcctgaaaa ccaagctttg 3050

 atttagattg agtaagattt acccagaatg tcagattcct ttccctttag 3100

 cacgtttaaa gttctgtgta tttaattgta aactgtacta gtctgtgtgg 3150

 gactgtacac actttattta cttcgttttg gttaagttgg cttctgtttc 3200

 tagttgagga gtttcctaaa agttcataac agtgccattg tctttatatg 3250

 aacatagact agagaaaccg tcctcttttt ccatcataat tctaatctaa 3300

 caatggaaga tttgcccatt tacacttttg agactttttg gtggatgtaa 3350

 ataaccccat tctttgcttg aacacagtat tttcccaata gcactttcat 3400

 tgccagtgtc tttctttggt gcctttcctg ttcagcattc ttagcctgtg 3450

 gcagtaaaga gaaactttgt gctacatgac gacaaagctg ctaaatctcc 3500

 tattttttta aaatcactaa cattatattg caatgaagga aataaaaaag 3550

 tctctattta aattcttttt taaattttct tcagttggtg tgtttttggg 3600

 atgtcttatt tttagatggt tacactgtta gaacactatt ttcagaatct 3650

 gaatgtaatt tgtgtaataa agtgttttca gagcaaaaaa aaaaaaaaa 3699

<210> 5346
<211> 887
<212> PRT
<213> Homo sapien

<400> 5346
 Met Ala Gly Arg Val Pro Ser Leu Leu Val Leu Leu Val Phe Pro
   1               5                  10                  15

 Ser Ser Cys Leu Ala Phe Arg Ser Pro Leu Ser Val Phe Lys Arg
                  20                  25                  30

 Phe Lys Glu Thr Thr Arg Pro Phe Ser Asn Glu Cys Leu Gly Thr
                  35                  40                  45

 Thr Arg Pro Val Val Pro Ile Asp Ser Ser Asp Phe Ala Leu Asp
                  50                  55                  60

 Ile Arg Met Pro Gly Val Thr Pro Lys Gln Ser Asp Thr Tyr Phe
                  65                  70                  75

 Cys Met Ser Met Arg Ile Pro Val Asp Glu Glu Ala Phe Val Ile
                  80                  85                  90

 Asp Phe Lys Pro Arg Ala Ser Met Asp Thr Val His His Met Leu
                  95                 100                 105

 Leu Phe Gly Cys Asn Met Pro Ser Ser Thr Gly Ser Tyr Trp Phe
                 110                 115                 120

 Cys Asp Glu Gly Thr Cys Thr Asp Lys Ala Asn Ile Leu Tyr Ala
                 125                 130                 135

 Trp Ala Arg Asn Ala Pro Pro Thr Arg Leu Pro Lys Gly Val Gly
                 140                 145                 150

 Phe Arg Val Gly Gly Glu Thr Gly Ser Lys Tyr Phe Val Leu Gln
                 155                 160                 165

 Val His Tyr Gly Asp Ile Ser Ala Phe Arg Asp Asn Asn Lys Asp
                 170                 175                 180

 Cys Ser Gly Val Ser Leu His Leu Thr Arg Leu Pro Gln Pro Leu
                 185                 190                 195

 Ile Ala Gly Met Tyr Leu Met Met Ser Val Asp Thr Val Ile Pro
                 200                 205                 210

 Ala Gly Glu Lys Val Val Asn Ser Asp Ile Ser Cys His Tyr Lys
                 215                 220                 225

 Asn Tyr Pro Met His Val Phe Ala Tyr Arg Val His Thr His His
                 230                 235                 240

 Leu Gly Lys Val Val Ser Gly Tyr Arg Val Arg Asn Gly Gln Trp
                 245                 250                 255

 Thr Leu Ile Gly Arg Gln Ser Pro Gln Leu Pro Gln Ala Phe Tyr
                 260                 265                 270

 Pro Val Gly His Pro Val Asp Val Ser Phe Gly Asp Leu Leu Ala
                 275                 280                 285

 Ala Arg Cys Val Phe Thr Gly Glu Gly Arg Thr Glu Ala Thr His
                 290                 295                 300

 Ile Gly Gly Thr Ser Ser Asp Glu Met Cys Asn Leu Tyr Ile Met
                 305                 310                 315

 Tyr Tyr Met Glu Ala Lys His Ala Val Ser Phe Met Thr Cys Thr
                 320                 325                 330

 Gln Asn Val Ala Pro Asp Met Phe Arg Thr Ile Pro Pro Glu Ala
                 335                 340                 345

 Asn Ile Pro Ile Pro Val Lys Ser Asp Met Val Met Met His Glu
                 350                 355                 360

 His His Lys Glu Thr Glu Tyr Lys Asp Lys Ile Pro Leu Leu Gln
                 365                 370                 375

 Gln Pro Lys Arg Glu Glu Glu Glu Val Leu Asp Gln Gly Asp Phe
                 380                 385                 390

 Tyr Ser Leu Leu Ser Lys Leu Leu Gly Glu Arg Glu Asp Val Val
                 395                 400                 405

 His Val His Lys Tyr Asn Pro Thr Glu Lys Ala Glu Ser Glu Ser
                 410                 415                 420

 Asp Leu Val Ala Glu Ile Ala Asn Val Val Gln Lys Lys Asp Leu
                 425                 430                 435

 Gly Arg Ser Asp Ala Arg Glu Gly Ala Glu His Glu Arg Gly Asn
                 440                 445                 450

 Ala Ile Leu Val Arg Asp Arg Ile His Lys Phe His Arg Leu Val
                 455                 460                 465

 Ser Thr Leu Arg Pro Pro Glu Ser Arg Val Phe Ser Leu Gln Gln
                 470                 475                 480

 Pro Pro Pro Gly Glu Gly Thr Trp Glu Pro Glu His Thr Gly Asp
                 485                 490                 495

 Phe His Met Glu Glu Ala Leu Asp Trp Pro Gly Val Tyr Leu Leu
                 500                 505                 510

 Pro Gly Gln Val Ser Gly Val Ala Leu Asp Pro Lys Asn Asn Leu
                 515                 520                 525

 Val Ile Phe His Arg Gly Asp His Val Trp Asp Gly Asn Ser Phe
                 530                 535                 540

 Asp Ser Lys Phe Val Tyr Gln Gln Ile Gly Leu Gly Pro Ile Glu
                 545                 550                 555

 Glu Asp Thr Ile Leu Val Ile Asp Pro Asn Asn Ala Ala Val Leu
                 560                 565                 570

 Gln Ser Ser Gly Lys Asn Leu Phe Tyr Leu Pro His Gly Leu Ser
                 575                 580                 585

 Ile Asp Lys Asp Gly Asn Tyr Trp Val Thr Asp Val Ala Leu His
                 590                 595                 600

 Gln Val Phe Lys Leu Asp Pro Asn Asn Lys Glu Gly Pro Val Leu
                 605                 610                 615

 Ile Leu Gly Arg Ser Met Gln Pro Gly Ser Asp Gln Asn His Phe
                 620                 625                 630

 Cys Gln Pro Thr Asp Val Ala Val Asp Pro Gly Thr Gly Ala Ile
                 635                 640                 645

 Tyr Val Ser Asp Gly Tyr Cys Asn Ser Arg Ile Val Gln Phe Ser
                 650                 655                 660

 Pro Ser Gly Lys Phe Ile Thr Gln Trp Gly Glu Glu Ser Ser Gly
                 665                 670                 675

 Ser Ser Pro Leu Pro Gly Gln Phe Thr Val Pro His Ser Leu Ala
                 680                 685                 690

 Leu Val Pro Leu Leu Gly Gln Leu Cys Val Ala Asp Arg Glu Asn
                 695                 700                 705

 Gly Arg Ile Gln Cys Phe Lys Thr Asp Thr Lys Glu Phe Val Arg
                 710                 715                 720

 Glu Ile Lys His Ser Ser Phe Gly Arg Asn Val Phe Ala Ile Ser
                 725                 730                 735

 Tyr Ile Pro Gly Leu Leu Phe Ala Val Asn Gly Lys Pro His Phe
                 740                 745                 750

 Gly Asp Gln Glu Pro Val Gln Gly Phe Val Met Asn Phe Ser Asn
                 755                 760                 765

 Gly Glu Ile Ile Asp Ile Phe Lys Pro Val Arg Lys His Phe Asp
                 770                 775                 780

 Met Pro His Asp Ile Val Ala Ser Glu Asp Gly Thr Val Tyr Ile
                 785                 790                 795

 Gly Asp Ala His Thr Asn Thr Val Trp Lys Phe Thr Leu Thr Glu
                 800                 805                 810

 Lys Leu Glu His Arg Ser Val Lys Lys Ala Gly Ile Glu Val Gln
                 815                 820                 825

 Glu Ile Lys Gly Lys Gly Ser Gly Gly Leu Asn Leu Gly Asn Phe
                 830                 835                 840

 Phe Ala Ser Arg Lys Gly Tyr Ser Arg Lys Gly Phe Asp Arg Leu
                 845                 850                 855

 Ser Thr Glu Gly Ser Asp Gln Glu Lys Glu Asp Asp Gly Ser Glu
                 860                 865                 870

 Ser Glu Glu Glu Tyr Ser Ala Pro Leu Pro Ala Leu Ala Pro Ser
                 875                 880                 885

 Ser Ser


<210> 5347
<211> 1028
<212> DNA
<213> Homo sapien

<400> 5347
 ggcacgagga cggcgcccgc cgcccgcccg gagcccgcga gcaaccccag 50

 tcccccccac ccgcgcgtgg cggcgccggc tccctagcca ccgcggcccc 100

 accctcttcc ggcctcagct gtccgggctg ctttcgcctc cgcctgtgga 150

 tgctgcgcct ctccgaacgc aacatgaagg tgctccttgc cgccgccctc 200

 atcgcggggt ccgtcttctt cctgctgctg ccgggacctt ctgcggccga 250

 tgagaagaag aaggggccca aagtcaccgt caaggtgtat tttgacctac 300

 gaattggaga tgaagatgta ggccgggtga tctttggtct cttcggaaag 350

 actgttccaa aaacagtgga taattttgtg gccttagcta caggagagaa 400

 aggatttggc tacaaaaaca gcaaattcca tcgtgtaatc aaggacttca 450

 tgatccaggg cggagacttc accaggggag atggcacagg aggaaagagc 500

 atctacggtg agcgcttccc cgatgagaac ttcaaactga agcactacgg 550

 gcctggctgg gtgagcatgg ccaacgcagg caaagacacc aacggctccc 600

 agttcttcat cacgacagtc aagacagcct ggctagatgg caagcatgtg 650

 gtgtttggca aagttctaga gggcatggag gtggtgcgga aggtggagag 700

 caccaagaca gacagccggg ataaacccct gaaggatgtg atcatcgcag 750

 actgcggcaa gatcgaggtg gagaagccct ttgccatcgc caaggagtag 800

 ggcacaggga catctttctt tgagtgaccg tctgtgcagg ccctgtagtc 850

 cgccacaggg ctttgagctg cactggcccc ggtgctggca tctggtggag 900

 cggacccact cccctcacat tccacaggcc catggactca cttttgtaac 950

 aaactcctac caaccctgac caataaaaaa aaatgtgggt tttttttttt 1000

 ttttaataaa aaaaaaaaaa aaaaaaaa 1028

<210> 5348
<211> 216
<212> PRT
<213> Homo sapien

<400> 5348
 Met Leu Arg Leu Ser Glu Arg Asn Met Lys Val Leu Leu Ala Ala
   1               5                  10                  15

 Ala Leu Ile Ala Gly Ser Val Phe Phe Leu Leu Leu Pro Gly Pro
                  20                  25                  30

 Ser Ala Ala Asp Glu Lys Lys Lys Gly Pro Lys Val Thr Val Lys
                  35                  40                  45

 Val Tyr Phe Asp Leu Arg Ile Gly Asp Glu Asp Val Gly Arg Val
                  50                  55                  60

 Ile Phe Gly Leu Phe Gly Lys Thr Val Pro Lys Thr Val Asp Asn
                  65                  70                  75

 Phe Val Ala Leu Ala Thr Gly Glu Lys Gly Phe Gly Tyr Lys Asn
                  80                  85                  90

 Ser Lys Phe His Arg Val Ile Lys Asp Phe Met Ile Gln Gly Gly
                  95                 100                 105

 Asp Phe Thr Arg Gly Asp Gly Thr Gly Gly Lys Ser Ile Tyr Gly
                 110                 115                 120

 Glu Arg Phe Pro Asp Glu Asn Phe Lys Leu Lys His Tyr Gly Pro
                 125                 130                 135

 Gly Trp Val Ser Met Ala Asn Ala Gly Lys Asp Thr Asn Gly Ser
                 140                 145                 150

 Gln Phe Phe Ile Thr Thr Val Lys Thr Ala Trp Leu Asp Gly Lys
                 155                 160                 165

 His Val Val Phe Gly Lys Val Leu Glu Gly Met Glu Val Val Arg
                 170                 175                 180

 Lys Val Glu Ser Thr Lys Thr Asp Ser Arg Asp Lys Pro Leu Lys
                 185                 190                 195

 Asp Val Ile Ile Ala Asp Cys Gly Lys Ile Glu Val Glu Lys Pro
                 200                 205                 210

 Phe Ala Ile Ala Lys Glu
                 215

<210> 5349
<211> 2372
<212> DNA
<213> Homo sapien

<400> 5349
 gggccgccgt cggcgcgctg ggtgcgggaa gggggctctg gatttcggtc 50

 cctccccttt ttcctctgag tctcggaacg ctccagctct cagaccctct 100

 tcctcccagg taaaggccgg gagaggaggg cgcatctctt ttccaggcac 150

 cccaccatgg gcaatgcctc caatgactcc cagtctgagg actgcgagac 200

 gcgacagtgg cttcccccag gcgaaagccc agccatcagc tccgtcatgt 250

 tctcggccgg ggtgctgggg aacctcatag cactggcgct gctggcgcgc 300

 cgctggcggg gggacgtggg gtgcagcgcc ggccgcagga gctccctctc 350

 cttgttccac gtgctggtga ccgagctggt gttcaccgac ctgctcggga 400

 cctgcctcat cagcccagtg gtactggctt cgtacgcgcg gaaccagacc 450

 ctggtggcac tggcgcccga gagccgcgcg tgcacctact tcgctttcgc 500

 catgaccttc ttcagcctgg ccacgatgct catgctcttc gccatggccc 550

 tggagcgcta cctctcgatc gggcacccct acttctacca gcgccgcgtc 600

 tcggcctccg ggggcctggc cgtgctgcct gtcatctatg cagtctccct 650

 gctcttctgc tcgctgccgc tgctggacta tgggcagtac gtccagtact 700

 gccccgggac ctggtgcttc atccggcacg ggcggaccgc ttacctgcag 750

 ctgtacgcca ccctgctgct gcttctcatt gtctcggtgc tcgcctgcaa 800

 cttcagtgtc attctcaacc tcatccgcat gcaccgccga agccggagaa 850

 gccgctgcgg accttccctg ggcagtggcc ggggcggccc cggggcccgc 900

 aggagagggg aaagggtgtc catggcggag gagacggacc acctcattct 950

 cctggctatc atgaccatca ccttcgccgt ctgctccttg cctttcacga 1000

 tttttgcata tatgaatgaa acctcttccc gaaaggaaaa atgggacctc 1050

 caagctctta ggtttttatc aattaattca ataattgacc cttgggtctt 1100

 tgccatcctt aggcctcctg ttctgagact aatgcgttca gtcctctgtt 1150

 gtcggatttc attaagaaca caagatgcaa cacaaacttc ctgttctaca 1200

 cagtcagatg ccagtaaaca ggctgacctt tgaggtcagt agtttaaaag 1250

 ttcttagtta tatagcatct ggaagatcat tttgaaattg ttccctggag 1300

 aaatgaaaac agtgtgtaaa caaaatgaag ctgccctaat aaaaaggagt 1350

 atacaaacat ttaagctgtg gtcaaggcta cagatgtgct gacaaggcac 1400

 ttcatgtaaa gtgtcagaag gagctacaaa acctaccctc aatgagcatg 1450

 gtacttggcc tttggaggaa caatcggctg cattgaagat ccagctgcct 1500

 attgatttaa gctttcctgt tgaatgacaa agtatgtggt tttgtaattt 1550

 gtttgaaacc ccaaacagtg actgtacttt ctattttaat cttgctacta 1600

 ccgttataca catatagtgt acagccagac cagattaaac ttcatatgta 1650

 atctctagga agtcaatatg tggaagcaac caagcctgct gtcttgtgat 1700

 cacttagcga accctttatt tgaacaatga agttgaaaat cataggcacc 1750

 ttttactgtg atgtttgtgt atgtgggagt actctcatca ctacagtatt 1800

 actcttacaa gagtggactc agtgggttaa catcagtttt gtttactcat 1850

 cctccaggaa ctgcaggtca agttgtcagg ttatttattt tataatgtcc 1900

 atatgctaat agtgatcaag aagactttag gaatggttct ctcaacaaga 1950

 aataatagaa atgtctcaag gcagttaatt ctcattaata ctcttattat 2000

 cctatttctg ggggaggatg tacgtggcca tgtatgaagc caaatattag 2050

 gcttaaaaac tgaaaaatct ggttcattct tcagatatac tggaaccctt 2100

 ttaaagttga tattggggcc atgagtaaaa tagattttat aagatgactg 2150

 tgttgtacca aaattcatct gtctatattt tatttagggg aacatggttt 2200

 gactcatctt atatgggaaa ccatgtagca gtgagtcata tcttaatata 2250

 tttctaaatg tttggcatgt aaatgtaaac tcagcatcaa aatatttcag 2300

 tgaatttgca ctgtttaatc atagttactg tgtaaactca tctgaaatgt 2350

 tacaaaaata aactataaaa ca 2372

<210> 5350
<211> 358
<212> PRT
<213> Homo sapien

<400> 5350
 Met Gly Asn Ala Ser Asn Asp Ser Gln Ser Glu Asp Cys Glu Thr
   1               5                  10                  15

 Arg Gln Trp Leu Pro Pro Gly Glu Ser Pro Ala Ile Ser Ser Val
                  20                  25                  30

 Met Phe Ser Ala Gly Val Leu Gly Asn Leu Ile Ala Leu Ala Leu
                  35                  40                  45

 Leu Ala Arg Arg Trp Arg Gly Asp Val Gly Cys Ser Ala Gly Arg
                  50                  55                  60

 Arg Ser Ser Leu Ser Leu Phe His Val Leu Val Thr Glu Leu Val
                  65                  70                  75

 Phe Thr Asp Leu Leu Gly Thr Cys Leu Ile Ser Pro Val Val Leu
                  80                  85                  90

 Ala Ser Tyr Ala Arg Asn Gln Thr Leu Val Ala Leu Ala Pro Glu
                  95                 100                 105

 Ser Arg Ala Cys Thr Tyr Phe Ala Phe Ala Met Thr Phe Phe Ser
                 110                 115                 120

 Leu Ala Thr Met Leu Met Leu Phe Ala Met Ala Leu Glu Arg Tyr
                 125                 130                 135

 Leu Ser Ile Gly His Pro Tyr Phe Tyr Gln Arg Arg Val Ser Ala
                 140                 145                 150

 Ser Gly Gly Leu Ala Val Leu Pro Val Ile Tyr Ala Val Ser Leu
                 155                 160                 165

 Leu Phe Cys Ser Leu Pro Leu Leu Asp Tyr Gly Gln Tyr Val Gln
                 170                 175                 180

 Tyr Cys Pro Gly Thr Trp Cys Phe Ile Arg His Gly Arg Thr Ala
                 185                 190                 195

 Tyr Leu Gln Leu Tyr Ala Thr Leu Leu Leu Leu Leu Ile Val Ser
                 200                 205                 210

 Val Leu Ala Cys Asn Phe Ser Val Ile Leu Asn Leu Ile Arg Met
                 215                 220                 225

 His Arg Arg Ser Arg Arg Ser Arg Cys Gly Pro Ser Leu Gly Ser
                 230                 235                 240

 Gly Arg Gly Gly Pro Gly Ala Arg Arg Arg Gly Glu Arg Val Ser
                 245                 250                 255

 Met Ala Glu Glu Thr Asp His Leu Ile Leu Leu Ala Ile Met Thr
                 260                 265                 270

 Ile Thr Phe Ala Val Cys Ser Leu Pro Phe Thr Ile Phe Ala Tyr
                 275                 280                 285

 Met Asn Glu Thr Ser Ser Arg Lys Glu Lys Trp Asp Leu Gln Ala
                 290                 295                 300

 Leu Arg Phe Leu Ser Ile Asn Ser Ile Ile Asp Pro Trp Val Phe
                 305                 310                 315

 Ala Ile Leu Arg Pro Pro Val Leu Arg Leu Met Arg Ser Val Leu
                 320                 325                 330

 Cys Cys Arg Ile Ser Leu Arg Thr Gln Asp Ala Thr Gln Thr Ser
                 335                 340                 345

 Cys Ser Thr Gln Ser Asp Ala Ser Lys Gln Ala Asp Leu
                 350                 355

<210> 5351
<211> 1958
<212> DNA
<213> Homo sapien

<400> 5351
 cggcacagcc tcacacctga acgctgtcct cccgcagacg agaccggcgg 50

 gcactgcaaa gctgggactc gtctttgaag gaaaaaaaat agcgagtaag 100

 aaatccagca ccattcttca ctgacccatc ccgctgcacc tcttgtttcc 150

 caagtttttg aaagctggca actctgacct cggtgtccaa aaatcgacag 200

 ccactgagac cggctttgag aagccgaaga tttggcagtt tccagactga 250

 gcaggacaag gtgaaagcag gttggaggcg ggtccaggac atctgagggc 300

 tgaccctggg ggctcgtgag gctgccaccg ctgctgccgc tacagaccca 350

 gccttgcact ccaaggctgc gcaccgccag ccactatcat gtccactccc 400

 ggggtcaatt cgtccgcctc cttgagcccc gaccggctga acagcccagt 450

 gaccatcccg gcggtgatgt tcatcttcgg ggtggtgggc aacctggtgg 500

 ccatcgtggt gctgtgcaag tcgcgcaagg agcagaagga gacgaccttc 550

 tacacgctgg tatgtgggct ggctgtcacc gacctgttgg gcactttgtt 600

 ggtgagcccg gtgaccatcg ccacgtacat gaagggccaa tggcccgggg 650

 gccagccgct gtgcgagtac agcaccttca ttctgctctt cttcagcctg 700

 tccggcctca gcatcatctg cgccatgagt gtcgagcgct acctggccat 750

 caaccatgcc tatttctaca gccactacgt ggacaagcga ttggcgggcc 800

 tcacgctctt tgcagtctat gcgtccaacg tgctcttttg cgcgctgccc 850

 aacatgggtc tcggtagctc gcggctgcag tacccagaca cctggtgctt 900

 catcgactgg accaccaacg tgacggcgca cgccgcctac tcctacatgt 950

 acgcgggctt cagctccttc ctcattctcg ccaccgtcct ctgcaacgtg 1000

 cttgtgtgcg gcgcgctgct ccgcatgcac cgccagttca tgcgccgcac 1050

 ctcgctgggc accgagcagc accacgcggc cgcggccgcc tcggttgcct 1100

 cccggggcca ccccgctgcc tccccagcct tgccgcgcct cagcgacttt 1150

 cggcgccgcc ggagcttccg ccgcatcgcg ggcgccgaga tccagatggt 1200

 catcttactc attgccacct ccctggtggt gctcatctgc tccatcccgc 1250

 tcgtggtgcg agtattcgtc aaccagttat atcagccaag tttggagcga 1300

 gaagtcagta aaaatccaga tttgcaggcc atccgaattg cttctgtgaa 1350

 ccccatccta gacccctgga tatatatcct cctgagaaag acagtgctca 1400

 gtaaagcaat agagaagatc aaatgcctct tctgccgcat tggcgggtcc 1450

 cgcagggagc gctccggaca gcactgctca gacagtcaaa ggacatcttc 1500

 tgccatgtca ggccactctc gctccttcat ctcccgggag ctgaaggaga 1550

 tcagcagtac atctcagacc ctcctgccag acctctcact gccagacctc 1600

 agtgaaaatg gccttggagg caggaatttg cttccaggtg tgcctggcat 1650

 gggcctggcc caggaagaca ccacctcact gaggactttg cgaatatcag 1700

 agacctcaga ctcttcacag ggtcaggact cagagagtgt cttactggtg 1750

 gatgaggctg gtgggagcgg cagggctggg cctgccccta aggggagctc 1800

 cctgcaagtc acatttccca gtgaaacact gaacttatca gaaaaatgta 1850

 tataataggc aaggaaagaa atacagtact gtttctggac ccttataaaa 1900

 tcctgtgcaa tagacacata catgtcacat ttagctgtgc tcagaagggc 1950

 tatcatca 1958

<210> 5352
<211> 488
<212> PRT
<213> Homo sapien

<400> 5352
 Met Ser Thr Pro Gly Val Asn Ser Ser Ala Ser Leu Ser Pro Asp
   1               5                  10                  15

 Arg Leu Asn Ser Pro Val Thr Ile Pro Ala Val Met Phe Ile Phe
                  20                  25                  30

 Gly Val Val Gly Asn Leu Val Ala Ile Val Val Leu Cys Lys Ser
                  35                  40                  45

 Arg Lys Glu Gln Lys Glu Thr Thr Phe Tyr Thr Leu Val Cys Gly
                  50                  55                  60

 Leu Ala Val Thr Asp Leu Leu Gly Thr Leu Leu Val Ser Pro Val
                  65                  70                  75

 Thr Ile Ala Thr Tyr Met Lys Gly Gln Trp Pro Gly Gly Gln Pro
                  80                  85                  90

 Leu Cys Glu Tyr Ser Thr Phe Ile Leu Leu Phe Phe Ser Leu Ser
                  95                 100                 105

 Gly Leu Ser Ile Ile Cys Ala Met Ser Val Glu Arg Tyr Leu Ala
                 110                 115                 120

 Ile Asn His Ala Tyr Phe Tyr Ser His Tyr Val Asp Lys Arg Leu
                 125                 130                 135

 Ala Gly Leu Thr Leu Phe Ala Val Tyr Ala Ser Asn Val Leu Phe
                 140                 145                 150

 Cys Ala Leu Pro Asn Met Gly Leu Gly Ser Ser Arg Leu Gln Tyr
                 155                 160                 165

 Pro Asp Thr Trp Cys Phe Ile Asp Trp Thr Thr Asn Val Thr Ala
                 170                 175                 180

 His Ala Ala Tyr Ser Tyr Met Tyr Ala Gly Phe Ser Ser Phe Leu
                 185                 190                 195

 Ile Leu Ala Thr Val Leu Cys Asn Val Leu Val Cys Gly Ala Leu
                 200                 205                 210

 Leu Arg Met His Arg Gln Phe Met Arg Arg Thr Ser Leu Gly Thr
                 215                 220                 225

 Glu Gln His His Ala Ala Ala Ala Ala Ser Val Ala Ser Arg Gly
                 230                 235                 240

 His Pro Ala Ala Ser Pro Ala Leu Pro Arg Leu Ser Asp Phe Arg
                 245                 250                 255

 Arg Arg Arg Ser Phe Arg Arg Ile Ala Gly Ala Glu Ile Gln Met
                 260                 265                 270

 Val Ile Leu Leu Ile Ala Thr Ser Leu Val Val Leu Ile Cys Ser
                 275                 280                 285

 Ile Pro Leu Val Val Arg Val Phe Val Asn Gln Leu Tyr Gln Pro
                 290                 295                 300

 Ser Leu Glu Arg Glu Val Ser Lys Asn Pro Asp Leu Gln Ala Ile
                 305                 310                 315

 Arg Ile Ala Ser Val Asn Pro Ile Leu Asp Pro Trp Ile Tyr Ile
                 320                 325                 330

 Leu Leu Arg Lys Thr Val Leu Ser Lys Ala Ile Glu Lys Ile Lys
                 335                 340                 345

 Cys Leu Phe Cys Arg Ile Gly Gly Ser Arg Arg Glu Arg Ser Gly
                 350                 355                 360

 Gln His Cys Ser Asp Ser Gln Arg Thr Ser Ser Ala Met Ser Gly
                 365                 370                 375

 His Ser Arg Ser Phe Ile Ser Arg Glu Leu Lys Glu Ile Ser Ser
                 380                 385                 390

 Thr Ser Gln Thr Leu Leu Pro Asp Leu Ser Leu Pro Asp Leu Ser
                 395                 400                 405

 Glu Asn Gly Leu Gly Gly Arg Asn Leu Leu Pro Gly Val Pro Gly
                 410                 415                 420

 Met Gly Leu Ala Gln Glu Asp Thr Thr Ser Leu Arg Thr Leu Arg
                 425                 430                 435

 Ile Ser Glu Thr Ser Asp Ser Ser Gln Gly Gln Asp Ser Glu Ser
                 440                 445                 450

 Val Leu Leu Val Asp Glu Ala Gly Gly Ser Gly Arg Ala Gly Pro
                 455                 460                 465

 Ala Pro Lys Gly Ser Ser Leu Gln Val Thr Phe Pro Ser Glu Thr
                 470                 475                 480

 Leu Asn Leu Ser Glu Lys Cys Ile
                 485

<210> 5353
<211> 4465
<212> DNA
<213> Homo sapien

<400> 5353
 caattgtcat acgacttgca gtgagcgtca ggagcacgtc caggaactcc 50

 tcagcagcgc ctccttcagc tccacagcca gacgccctca gacagcaaag 100

 cctacccccg cgccgcgccc tgcccgccgc tcggatgctc gcccgcgccc 150

 tgctgctgtg cgcggtcctg gcgctcagcc atacagcaaa tccttgctgt 200

 tcccacccat gtcaaaaccg aggtgtatgt atgagtgtgg gatttgacca 250

 gtataagtgc gattgtaccc ggacaggatt ctatggagaa aactgctcaa 300

 caccggaatt tttgacaaga ataaaattat ttctgaaacc cactccaaac 350

 acagtgcact acatacttac ccacttcaag ggattttgga acgttgtgaa 400

 taacattccc ttccttcgaa atgcaattat gagttatgtc ttgacatcca 450

 gatcacattt gattgacagt ccaccaactt acaatgctga ctatggctac 500

 aaaagctggg aagccttctc taacctctcc tattatacta gagcccttcc 550

 tcctgtgcct gatgattgcc cgactccctt gggtgtcaaa ggtaaaaagc 600

 agcttcctga ttcaaatgag attgtggaaa aattgcttct aagaagaaag 650

 ttcatccctg atccccaggg ctcaaacatg atgtttgcat tctttgccca 700

 gcacttcacg catcagtttt tcaagacaga tcataagcga gggccagctt 750

 tcaccaacgg gctgggccat ggggtggact taaatcatat ttacggtgaa 800

 actctggcta gacagcgtaa actgcgcctt ttcaaggatg gaaaaatgaa 850

 atatcagata attgatggag agatgtatcc tcccacagtc aaagatactc 900

 aggcagagat gatctaccct cctcaagtcc ctgagcatct acggtttgct 950

 gtggggcagg aggtctttgg tctggtgcct ggtctgatga tgtatgccac 1000

 aatctggctg cgggaacaca acagagtatg cgatgtgctt aaacaggagc 1050

 atcctgaatg gggtgatgag cagttgttcc agacaagcag gctaatactg 1100

 ataggagaga ctattaagat tgtgattgaa gattatgtgc aacacttgag 1150

 tggctatcac ttcaaactga aatttgaccc agaactactt ttcaacaaac 1200

 aattccagta ccaaaatcgt attgctgctg aatttaacac cctctatcac 1250

 tggcatcccc ttctgcctga cacctttcaa attcatgacc agaaatacaa 1300

 ctatcaacag tttatctaca acaactctat attgctggaa catggaatta 1350

 cccagtttgt tgaatcattc accaggcaaa ttgctggcag ggttgctggt 1400

 ggtaggaatg ttccacccgc agtacagaaa gtatcacagg cttccattga 1450

 ccagagcagg cagatgaaat accagtcttt taatgagtac cgcaaacgct 1500

 ttatgctgaa gccctatgaa tcatttgaag aacttacagg agaaaaggaa 1550

 atgtctgcag agttggaagc actctatggt gacatcgatg ctgtggagct 1600

 gtatcctgcc cttctggtag aaaagcctcg gccagatgcc atctttggtg 1650

 aaaccatggt agaagttgga gcaccattct ccttgaaagg acttatgggt 1700

 aatgttatat gttctcctgc ctactggaag ccaagcactt ttggtggaga 1750

 agtgggtttt caaatcatca acactgcctc aattcagtct ctcatctgca 1800

 ataacgtgaa gggctgtccc tttacttcat tcagtgttcc agatccagag 1850

 ctcattaaaa cagtcaccat caatgcaagt tcttcccgct ccggactaga 1900

 tgatatcaat cccacagtac tactaaaaga acgttcgact gaactgtaga 1950

 agtctaatga tcatatttat ttatttatat gaaccatgtc tattaattta 2000

 attatttaat aatatttata ttaaactcct tatgttactt aacatcttct 2050

 gtaacagaag tcagtactcc tgttgcggag aaaggagtca tacttgtgaa 2100

 gacttttatg tcactactct aaagattttg ctgttgctgt taagtttgga 2150

 aaacagtttt tattctgttt tataaaccag agagaaatga gttttgacgt 2200

 ctttttactt gaatttcaac ttatattata agaacgaaag taaagatgtt 2250

 tgaatactta aacactatca caagatggca aaatgctgaa agtttttaca 2300

 ctgtcgatgt ttccaatgca tcttccatga tgcattagaa gtaactaatg 2350

 tttgaaattt taaagtactt ttggttattt ttctgtcatc aaacaaaaac 2400

 aggtatcagt gcattattaa atgaatattt aaattagaca ttaccagtaa 2450

 tttcatgtct actttttaaa atcagcaatg aaacaataat ttgaaatttc 2500

 taaattcata gggtagaatc acctgtaaaa gcttgtttga tttcttaaag 2550

 ttattaaact tgtacatata ccaaaaagaa gctgtcttgg atttaaatct 2600

 gtaaaatcag atgaaatttt actacaattg cttgttaaaa tattttataa 2650

 gtgatgttcc tttttcacca agagtataaa cctttttagt gtgactgtta 2700

 aaacttcctt ttaaatcaaa atgccaaatt tattaaggtg gtggagccac 2750

 tgcagtgtta tctcaaaata agaatatttt gttgagatat tccagaattt 2800

 gtttatatgg ctggtaacat gtaaaatcta tatcagcaaa agggtctacc 2850

 tttaaaataa gcaataacaa agaagaaaac caaattattg ttcaaattta 2900

 ggtttaaact tttgaagcaa actttttttt atccttgtgc actgcaggcc 2950

 tggtactcag attttgctat gaggttaatg aagtaccaag ctgtgcttga 3000

 ataacgatat gttttctcag attttctgtt gtacagttta atttagcagt 3050

 ccatatcaca ttgcaaaagt agcaatgacc tcataaaata cctcttcaaa 3100

 atgcttaaat tcatttcaca cattaatttt atctcagtct tgaagccaat 3150

 tcagtaggtg cattggaatc aagcctggct acctgcatgc tgttcctttt 3200

 cttttcttct tttagccatt ttgctaagag acacagtctt ctcatcactt 3250

 cgtttctcct attttgtttt actagtttta agatcagagt tcactttctt 3300

 tggactctgc ctatattttc ttacctgaac ttttgcaagt tttcaggtaa 3350

 acctcagctc aggactgcta tttagctcct cttaagaaga ttaaaagaga 3400

 aaaaaaaagg cccttttaaa aatagtatac acttatttta agtgaaaagc 3450

 agagaatttt atttatagct aattttagct atctgtaacc aagatggatg 3500

 caaagaggct agtgcctcag agagaactgt acggggtttg tgactggaaa 3550

 aagttacgtt cccattctaa ttaatgccct ttcttattta aaaacaaaac 3600

 caaatgatat ctaagtagtt ctcagcaata ataataatga cgataatact 3650

 tcttttccac atctcattgt cactgacatt taatggtact gtatattact 3700

 taatttattg aagattatta tttatgtctt attaggacac tatggttata 3750

 aactgtgttt aagcctacaa tcattgattt ttttttgtta tgtcacaatc 3800

 agtatatttt ctttggggtt acctctctga atattatgta aacaatccaa 3850

 agaaatgatt gtattaagat ttgtgaataa atttttagaa atctgattgg 3900

 catattgaga tatttaaggt tgaatgtttg tccttaggat aggcctatgt 3950

 gctagcccac aaagaatatt gtctcattag cctgaatgtg ccataagact 4000

 gaccttttaa aatgttttga gggatctgtg gatgcttcgt taatttgttc 4050

 agccacaatt tattgagaaa atattctgtg tcaagcactg tgggttttaa 4100

 tatttttaaa tcaaacgctg attacagata atagtattta tataaataat 4150

 tgaaaaaaat tttcttttgg gaagagggag aaaatgaaat aaatatcatt 4200

 aaagataact caggagaatc ttctttacaa ttttacgttt agaatgttta 4250

 aggttaagaa agaaatagtc aatatgcttg tataaaacac tgttcactgt 4300

 tttttttaaa aaaaaaactt gatttgttat taacattgat ctgctgacaa 4350

 aacctgggaa tttgggttgt gtatgcgaat gtttcagtgc ctcagacaaa 4400

 tgtgtattta acttatgtaa aagataagtc tggaaataaa tgtctgttta 4450

 tttttgtact attta 4465

<210> 5354
<211> 604
<212> PRT
<213> Homo sapien

<400> 5354
 Met Leu Ala Arg Ala Leu Leu Leu Cys Ala Val Leu Ala Leu Ser
   1               5                  10                  15

 His Thr Ala Asn Pro Cys Cys Ser His Pro Cys Gln Asn Arg Gly
                  20                  25                  30

 Val Cys Met Ser Val Gly Phe Asp Gln Tyr Lys Cys Asp Cys Thr
                  35                  40                  45

 Arg Thr Gly Phe Tyr Gly Glu Asn Cys Ser Thr Pro Glu Phe Leu
                  50                  55                  60

 Thr Arg Ile Lys Leu Phe Leu Lys Pro Thr Pro Asn Thr Val His
                  65                  70                  75

 Tyr Ile Leu Thr His Phe Lys Gly Phe Trp Asn Val Val Asn Asn
                  80                  85                  90

 Ile Pro Phe Leu Arg Asn Ala Ile Met Ser Tyr Val Leu Thr Ser
                  95                 100                 105

 Arg Ser His Leu Ile Asp Ser Pro Pro Thr Tyr Asn Ala Asp Tyr
                 110                 115                 120

 Gly Tyr Lys Ser Trp Glu Ala Phe Ser Asn Leu Ser Tyr Tyr Thr
                 125                 130                 135

 Arg Ala Leu Pro Pro Val Pro Asp Asp Cys Pro Thr Pro Leu Gly
                 140                 145                 150

 Val Lys Gly Lys Lys Gln Leu Pro Asp Ser Asn Glu Ile Val Glu
                 155                 160                 165

 Lys Leu Leu Leu Arg Arg Lys Phe Ile Pro Asp Pro Gln Gly Ser
                 170                 175                 180

 Asn Met Met Phe Ala Phe Phe Ala Gln His Phe Thr His Gln Phe
                 185                 190                 195

 Phe Lys Thr Asp His Lys Arg Gly Pro Ala Phe Thr Asn Gly Leu
                 200                 205                 210

 Gly His Gly Val Asp Leu Asn His Ile Tyr Gly Glu Thr Leu Ala
                 215                 220                 225

 Arg Gln Arg Lys Leu Arg Leu Phe Lys Asp Gly Lys Met Lys Tyr
                 230                 235                 240

 Gln Ile Ile Asp Gly Glu Met Tyr Pro Pro Thr Val Lys Asp Thr
                 245                 250                 255

 Gln Ala Glu Met Ile Tyr Pro Pro Gln Val Pro Glu His Leu Arg
                 260                 265                 270

 Phe Ala Val Gly Gln Glu Val Phe Gly Leu Val Pro Gly Leu Met
                 275                 280                 285

 Met Tyr Ala Thr Ile Trp Leu Arg Glu His Asn Arg Val Cys Asp
                 290                 295                 300

 Val Leu Lys Gln Glu His Pro Glu Trp Gly Asp Glu Gln Leu Phe
                 305                 310                 315

 Gln Thr Ser Arg Leu Ile Leu Ile Gly Glu Thr Ile Lys Ile Val
                 320                 325                 330

 Ile Glu Asp Tyr Val Gln His Leu Ser Gly Tyr His Phe Lys Leu
                 335                 340                 345

 Lys Phe Asp Pro Glu Leu Leu Phe Asn Lys Gln Phe Gln Tyr Gln
                 350                 355                 360

 Asn Arg Ile Ala Ala Glu Phe Asn Thr Leu Tyr His Trp His Pro
                 365                 370                 375

 Leu Leu Pro Asp Thr Phe Gln Ile His Asp Gln Lys Tyr Asn Tyr
                 380                 385                 390

 Gln Gln Phe Ile Tyr Asn Asn Ser Ile Leu Leu Glu His Gly Ile
                 395                 400                 405

 Thr Gln Phe Val Glu Ser Phe Thr Arg Gln Ile Ala Gly Arg Val
                 410                 415                 420

 Ala Gly Gly Arg Asn Val Pro Pro Ala Val Gln Lys Val Ser Gln
                 425                 430                 435

 Ala Ser Ile Asp Gln Ser Arg Gln Met Lys Tyr Gln Ser Phe Asn
                 440                 445                 450

 Glu Tyr Arg Lys Arg Phe Met Leu Lys Pro Tyr Glu Ser Phe Glu
                 455                 460                 465

 Glu Leu Thr Gly Glu Lys Glu Met Ser Ala Glu Leu Glu Ala Leu
                 470                 475                 480

 Tyr Gly Asp Ile Asp Ala Val Glu Leu Tyr Pro Ala Leu Leu Val
                 485                 490                 495

 Glu Lys Pro Arg Pro Asp Ala Ile Phe Gly Glu Thr Met Val Glu
                 500                 505                 510

 Val Gly Ala Pro Phe Ser Leu Lys Gly Leu Met Gly Asn Val Ile
                 515                 520                 525

 Cys Ser Pro Ala Tyr Trp Lys Pro Ser Thr Phe Gly Gly Glu Val
                 530                 535                 540

 Gly Phe Gln Ile Ile Asn Thr Ala Ser Ile Gln Ser Leu Ile Cys
                 545                 550                 555

 Asn Asn Val Lys Gly Cys Pro Phe Thr Ser Phe Ser Val Pro Asp
                 560                 565                 570

 Pro Glu Leu Ile Lys Thr Val Thr Ile Asn Ala Ser Ser Ser Arg
                 575                 580                 585

 Ser Gly Leu Asp Asp Ile Asn Pro Thr Val Leu Leu Lys Glu Arg
                 590                 595                 600

 Ser Thr Glu Leu


<210> 5355
<211> 3682
<212> DNA
<213> Homo sapien

<400> 5355
 gcgagcgcag cggagcctgg agagaaggcg ctgggctgcg agggcgcgag 50

 ggcgcgaggg cagggggcaa ccggaccccg cccgcaccca tggcgcccgt 100

 cgccgtctgg gccgcgctgg ccgtcggact ggagctctgg gctgcggcgc 150

 acgccttgcc cgcccaggtg gcatttacac cctacgcccc ggagcccggg 200

 agcacatgcc ggctcagaga atactatgac cagacagctc agatgtgctg 250

 cagcaaatgc tcgccgggcc aacatgcaaa agtcttctgt accaagacct 300

 cggacaccgt gtgtgactcc tgtgaggaca gcacatacac ccagctctgg 350

 aactgggttc ccgagtgctt gagctgtggc tcccgctgta gctctgacca 400

 ggtggaaact caagcctgca ctcgggaaca gaaccgcatc tgcacctgca 450

 ggcccggctg gtactgcgcg ctgagcaagc aggaggggtg ccggctgtgc 500

 gcgccgctgc gcaagtgccg cccgggcttc ggcgtggcca gaccaggaac 550

 tgaaacatca gacgtggtgt gcaagccctg tgccccgggg acgttctcca 600

 acacgacttc atccacggat atttgcaggc cccaccagat ctgtaacgtg 650

 gtggccatcc ctgggaatgc aagcatggat gcagtctgca cgtccacgtc 700

 ccccacccgg agtatggccc caggggcagt acacttaccc cagccagtgt 750

 ccacacgatc ccaacacacg cagccaactc cagaacccag cactgctcca 800

 agcacctcct tcctgctccc aatgggcccc agccccccag ctgaagggag 850

 cactggcgac ttcgctcttc cagttggact gattgtgggt gtgacagcct 900

 tgggtctact aataatagga gtggtgaact gtgtcatcat gacccaggtg 950

 aaaaagaagc ccttgtgcct gcagagagaa gccaaggtgc ctcacttgcc 1000

 tgccgataag gcccggggta cacagggccc cgagcagcag cacctgctga 1050

 tcacagcgcc gagctccagc agcagctccc tggagagctc ggccagtgcg 1100

 ttggacagaa gggcgcccac tcggaaccag ccacaggcac caggcgtgga 1150

 ggccagtggg gccggggagg cccgggccag caccgggagc tcagattctt 1200

 cccctggtgg ccatgggacc caggtcaatg tcacctgcat cgtgaacgtc 1250

 tgtagcagct ctgaccacag ctcacagtgc tcctcccaag ccagctccac 1300

 aatgggagac acagattcca gcccctcgga gtccccgaag gacgagcagg 1350

 tccccttctc caaggaggaa tgtgcctttc ggtcacagct ggagacgcca 1400

 gagaccctgc tggggagcac cgaagagaag cccctgcccc ttggagtgcc 1450

 tgatgctggg atgaagccca gttaaccagg ccggtgtggg ctgtgtcgta 1500

 gccaaggtgg gctgagccct ggcaggatga ccctgcgaag gggccctggt 1550

 ccttccaggc ccccaccact aggactctga ggctctttct gggccaagtt 1600

 cctctagtgc cctccacagc cgcagcctcc ctctgacctg caggccaaga 1650

 gcagaggcag cgagttgtgg aaagcctctg ctgccatggc gtgtccctct 1700

 cggaaggctg gctgggcatg gacgttcggg gcatgctggg gcaagtccct 1750

 gactctctgt gacctgcccc gcccagctgc acctgccagc ctggcttctg 1800

 gagcccttgg gttttttgtt tgtttgtttg tttgtttgtt tgtttctccc 1850

 cctgggctct gccccagctc tggcttccag aaaaccccag catccttttc 1900

 tgcagagggg ctttctggag aggagggatg ctgcctgagt cacccatgaa 1950

 gacaggacag tgcttcagcc tgaggctgag actgcgggat ggtcctgggg 2000

 ctctgtgcag ggaggaggtg gcagccctgt agggaacggg gtccttcaag 2050

 ttagctcagg aggcttggaa agcatcacct caggccaggt gcagtggctc 2100

 acgcctatga tcccagcact ttgggaggct gaggcgggtg gatcacctga 2150

 ggttaggagt tcgagaccag cctggccaac atggtaaaac cccatctcta 2200

 ctaaaaatac agaaattagc cgggcgtggt ggcgggcacc tatagtccca 2250

 gctactcaga agcctgaggc tgggaaatcg tttgaacccg ggaagcggag 2300

 gttgcaggga gccgagatca cgccactgca ctccagcctg ggcgacagag 2350

 cgagagtctg tctcaaaaga aaaaaaaaag caccgcctcc aaatgccaac 2400

 ttgtcctttt gtaccatggt gtgaaagtca gatgcccaga gggcccaggc 2450

 aggccaccat attcagtgct gtggcctggg caagataacg cacttctaac 2500

 tagaaatctg ccaatttttt aaaaaagtaa gtaccactca ggccaacaag 2550

 ccaacgacaa agccaaactc tgccagccac atccaacccc ccacctgcca 2600

 tttgcaccct ccgccttcac tccggtgtgc ctgcagcccc gcgcctcctt 2650

 ccttgctgtc ctaggccaca ccatctcctt tcagggaatt tcaggaacta 2700

 gagatgactg agtcctcgta gccatctctc tactcctacc tcagcctaga 2750

 ccctcctcct cccccagagg ggtgggttcc tcttccccac tccccacctt 2800

 caattcctgg gccccaaacg ggctgccctg ccactttggt acatggccag 2850

 tgtgatccca agtgccagtc ttgtgtctgc gtctgtgttg cgtgtcgtgg 2900

 gtgtgtgtag ccaaggtcgg taagttgaat ggcctgcctt gaagccactg 2950

 aagctgggat tcctccccat tagagtcagc cttccccctc ccagggccag 3000

 ggccctgcag aggggaaacc agtgtagcct tgcccggatt ctgggaggaa 3050

 gcaggttgag gggctcctgg aaaggctcag tctcaggagc atggggataa 3100

 aggagaaggc atgaaattgt ctagcagagc aggggcaggg tgataaattg 3150

 ttgataaatt ccactggact tgagcttggc agctgaacta ttggagggtg 3200

 ggagagccca gccattacca tggagacaag aagggttttc caccctggaa 3250

 tcaagatgtc agactggctg gctgcagtga cgtgcacctg tactcaggag 3300

 gctgagggga ggatcactgg agcccaggag tttgaggctg cagcgagcta 3350

 tgatcgcgcc actacactcc agcctgagca acagagtgag accctgtctc 3400

 ttaaagaaaa aaaaagtcag actgctggga ctggccaggt ttctgcccac 3450

 attggaccca catgaggaca tgatggagcg cacctgcccc ctggtggaca 3500

 gtcctgggag aacctcaggc ttccttggca tcacagggca gagccgggaa 3550

 gcgatgaatt tggagactct gtggggcctt ggttcccttg tgtgtgtgtg 3600

 ttgatcccaa gacaatgaaa gtttgcactg tatgctggac ggcattcctg 3650

 cttatcaata aacctgtttg ttttaaaaaa aa 3682

<210> 5356
<211> 461
<212> PRT
<213> Homo sapien

<400> 5356
 Met Ala Pro Val Ala Val Trp Ala Ala Leu Ala Val Gly Leu Glu
   1               5                  10                  15

 Leu Trp Ala Ala Ala His Ala Leu Pro Ala Gln Val Ala Phe Thr
                  20                  25                  30

 Pro Tyr Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu Tyr
                  35                  40                  45

 Tyr Asp Gln Thr Ala Gln Met Cys Cys Ser Lys Cys Ser Pro Gly
                  50                  55                  60

 Gln His Ala Lys Val Phe Cys Thr Lys Thr Ser Asp Thr Val Cys
                  65                  70                  75

 Asp Ser Cys Glu Asp Ser Thr Tyr Thr Gln Leu Trp Asn Trp Val
                  80                  85                  90

 Pro Glu Cys Leu Ser Cys Gly Ser Arg Cys Ser Ser Asp Gln Val
                  95                 100                 105

 Glu Thr Gln Ala Cys Thr Arg Glu Gln Asn Arg Ile Cys Thr Cys
                 110                 115                 120

 Arg Pro Gly Trp Tyr Cys Ala Leu Ser Lys Gln Glu Gly Cys Arg
                 125                 130                 135

 Leu Cys Ala Pro Leu Arg Lys Cys Arg Pro Gly Phe Gly Val Ala
                 140                 145                 150

 Arg Pro Gly Thr Glu Thr Ser Asp Val Val Cys Lys Pro Cys Ala
                 155                 160                 165

 Pro Gly Thr Phe Ser Asn Thr Thr Ser Ser Thr Asp Ile Cys Arg
                 170                 175                 180

 Pro His Gln Ile Cys Asn Val Val Ala Ile Pro Gly Asn Ala Ser
                 185                 190                 195

 Met Asp Ala Val Cys Thr Ser Thr Ser Pro Thr Arg Ser Met Ala
                 200                 205                 210

 Pro Gly Ala Val His Leu Pro Gln Pro Val Ser Thr Arg Ser Gln
                 215                 220                 225

 His Thr Gln Pro Thr Pro Glu Pro Ser Thr Ala Pro Ser Thr Ser
                 230                 235                 240

 Phe Leu Leu Pro Met Gly Pro Ser Pro Pro Ala Glu Gly Ser Thr
                 245                 250                 255

 Gly Asp Phe Ala Leu Pro Val Gly Leu Ile Val Gly Val Thr Ala
                 260                 265                 270

 Leu Gly Leu Leu Ile Ile Gly Val Val Asn Cys Val Ile Met Thr
                 275                 280                 285

 Gln Val Lys Lys Lys Pro Leu Cys Leu Gln Arg Glu Ala Lys Val
                 290                 295                 300

 Pro His Leu Pro Ala Asp Lys Ala Arg Gly Thr Gln Gly Pro Glu
                 305                 310                 315

 Gln Gln His Leu Leu Ile Thr Ala Pro Ser Ser Ser Ser Ser Ser
                 320                 325                 330

 Leu Glu Ser Ser Ala Ser Ala Leu Asp Arg Arg Ala Pro Thr Arg
                 335                 340                 345

 Asn Gln Pro Gln Ala Pro Gly Val Glu Ala Ser Gly Ala Gly Glu
                 350                 355                 360

 Ala Arg Ala Ser Thr Gly Ser Ser Asp Ser Ser Pro Gly Gly His
                 365                 370                 375

 Gly Thr Gln Val Asn Val Thr Cys Ile Val Asn Val Cys Ser Ser
                 380                 385                 390

 Ser Asp His Ser Ser Gln Cys Ser Ser Gln Ala Ser Ser Thr Met
                 395                 400                 405

 Gly Asp Thr Asp Ser Ser Pro Ser Glu Ser Pro Lys Asp Glu Gln
                 410                 415                 420

 Val Pro Phe Ser Lys Glu Glu Cys Ala Phe Arg Ser Gln Leu Glu
                 425                 430                 435

 Thr Pro Glu Thr Leu Leu Gly Ser Thr Glu Glu Lys Pro Leu Pro
                 440                 445                 450

 Leu Gly Val Pro Asp Ala Gly Met Lys Pro Ser
                 455                 460

<210> 5357
<211> 6196
<212> DNA
<213> Homo sapien

<400> 5357
 tgaggaactg cgtgtggagt cagcccagtc tggatgcaca ggaggatgct 50

 ggcggcacag tgagtgaggc ctggtgccag agctgtgcgg accccttgtt 100

 ggccatggag cagcaggccc agaggccctc tccccagccc tgcttgcctg 150

 cctcggagag gacagaggcc taggcccacg ggggagggtg ttggcagaca 200

 gatgccctcc aggccctggg gcctccttaa cggcccctta acgacacgcg 250

 tgccaagggt ggaggatgcc agccaagggg cgctacttcc tcaacgaggg 300

 cgaggagggc cctgaccaag atgcgctcta cgagaagtac cagctcacca 350

 gccagcatgg gccgctgctg ctcacgctcc tgctggtggc cgccactgcc 400

 tgcgtggccc tcatcatcat tgccttcagc cagggggacc cctccagaca 450

 ccaggccatt ctgggcatgg cgttcctggt gctggcggtg tttgcggccc 500

 tctctgtgct gatgtacgtc gagtgtctcc tgcggcgctg gctcagggcc 550

 ttggcgctgc tcacctgggc ctgcttggtg gcgctgggct atgtgctggt 600

 gttcgacgca tggacaaagg cggcctgtgc gtgggagcag gtgcccttct 650

 tcctgttcat tgtcttcgtg gtgtacacac tactgccctt cagcatgcgg 700

 ggcgctgtcg ccgttggggc cgtctccact gcctcccacc tcctggtgct 750

 cggttctttg atgggaggct tcacgacacc cagtgtccgg gtggggctgc 800

 agctgctggc caacgcagtc atcttcctgt gtgggaacct gacaggcgcc 850

 ttccacaagc accaaatgca ggatgcgtcc cgggacctct tcacctacac 900

 tgtgaagtgc atccagatcc gccggaagct gcgcatcgag aagcgccagc 950

 aggagaacct gctgctgtca gtgcttccgg cccacatctc catgggcatg 1000

 aagctggcca tcatcgaacg gctcaaggag catggtgacc gtcgctgcat 1050

 gcctgacaac aacttccaca gcctctacgt caagaggcac cagaatgtca 1100

 gcatcctcta tgcggacatc gtgggcttca cgcagctggc cagcgactgt 1150

 tctcccaagg agctggtggt ggtgctgaat gagctctttg gcaagttcga 1200

 ccagatcgcc aaggccaacg agtgcatgcg aatcaagatc ctcggcgact 1250

 gctactactg tgtatcgggc ctgcccgtgt cgctgcctac ccacgcccgg 1300

 aactgcgtga agatggggct ggacatgtgc caggccatca agcaggtgcg 1350

 ggaggccacg ggcgtggaca tcaacatgcg tgtgggcata cactcgggga 1400

 atgtgctgtg cggggtcatc gggctgcgca agtggcagta tgacgtgtgg 1450

 tcccacgacg tgtccctggc caaccggatg gaggcagccg gagtacccgg 1500

 ccgggtgcac atcacggagg ccacgctaaa gcacctggac aaggcgtacg 1550

 aggtggagga tgggcacggg cagcagcggg acccctacct caaggagatg 1600

 aacatccgca cctacctggt catcgacccc cggagccagc agccaccccc 1650

 gcccagccaa cacctcccca ggcccaaggg ggacgcggcc ctgaagatgc 1700

 gggcgtcagt gcgcatgacc cggtacctcg agtcctgggg ggcggcacgg 1750

 ccctttgcac atctcaacca ccgtgagagc gtgagcagtg gtgagaccca 1800

 cgtccccaac gggcggaggc ctaagagcgt tccccagcgc caccgccgga 1850

 ccccagacag aagcatgtcc cccaaggggc ggtcggagga tgactcgtac 1900

 gatgacgaga tgctgtcagc cattgagggg ctcagctcca cgaggccctg 1950

 ctgctccaag tccgatgact tctacacctt tgggtccatc ttcctggaga 2000

 agggctttga gcgcgagtac cgcctggcac ccatcccccg ggcccgccac 2050

 gactttgcct gcgccagcct gatcttcgtc tgcatcctgc tcgtccatgt 2100

 cctgctcatg cccaggacgg cggcactggg tgtgtccttc gggctggtgg 2150

 cctgtgtact ggggctggtg ctgggcctgt gctttgccac caagttctcg 2200

 aggtgctgcc cagctcgggg gacgctctgc actatctctg agagggtgga 2250

 gacacagccc ctgctgaggc tgaccctggc cgtcctgacc atcggcagcc 2300

 tgctcactgt ggccatcatc aacctgcccc tgatgccttt ccaagttcca 2350

 gagctgcctg ttggcaatga gacaggccta ctggccgcga gcagcaagac 2400

 aagagccctg tgtgagcccc tcccgtacta cacctgcagc tgtgtcctgg 2450

 gcttcatcgc ctgctcggtc ttcctgagga tgagcctgga gccaaaggtt 2500

 gtgctgctga cagtggccct ggtggcctac ctggtgctct tcaacctctc 2550

 cccatgctgg cagtgggact gctgcggcca aggcctgggc aacctcacca 2600

 agcccaacgg caccaccagt ggcaccccta gctgttcctg gaaggacctg 2650

 aagaccatga ccaatttcta cctggtcctg ttctacatca ccctgcttac 2700

 actctccaga cagattgact attactgccg cttggactgc ctatggaaga 2750

 agaagttcaa gaaggagcac gaggagtttg agaccatgga gaacgtgaac 2800

 cgccttcttc tggagaacgt cctgccagcc cacgtggctg cccactttat 2850

 cggtgacaag ttaaacgagg actggtacca tcagtcctat gactgcgtct 2900

 gtgtcatgtt tgcctccgtg ccggacttca aagtgttcta cacagagtgc 2950

 gatgtcaaca aagaagggct ggagtgccta cgcctgctca atgagatcat 3000

 tgccgacttc gacgagctcc tactgaagcc caagttcagc ggcgtggaga 3050

 agatcaagac catcggcagc acgtacatgg cagctgcagg gctcagcgtc 3100

 gcctcagggc acgagaacca ggagctggag cggcagcatg cccacattgg 3150

 tgtcatggtg gagttcagca tcgccctgat gagtaagctg gacggcatca 3200

 acaggcactc cttcaactcc ttccgcctcc gcgtcggcat aaaccatggg 3250

 cctgtgattg ctggagtgat tggggcccga aaacctcagt atgacatctg 3300

 gggaaacact gtcaatgtgg ccagccgaat ggaaagcact ggagaacttg 3350

 ggaaaatcca ggttaccgag gagacctgca ccatcctcca gggcctcggg 3400

 tactcttgtg aatgccgtgg cctgatcaac gtcaaaggca aaggcgagct 3450

 gaggacttac tttgtctgta cggacactgc caagtttcag gggctggggc 3500

 tgaactgagg gctcctgctg gattccgaaa aggccgggaa gccagtctcc 3550

 ttccctgaag caagcccagg agaagactct ccgccccacg ccaatcccaa 3600

 aggcatgcag atggctgtgc atgttggctt ctttggacct gcactggagg 3650

 atttctcaga cacatgcacc agattctggc tcgaagcagc cactgagcca 3700

 taatgcgcag gggaggccag aagctctgtg cctggtctgt aacagtttcc 3750

 aggccagctg gagaatgttc actggttcgg ggctgacttt gagatctttg 3800

 ttccctgagg tgccaggcag gcaactttag cacatgatga aaacagactt 3850

 ccacctcagt ggcctgtggg cacgcacaag tgaggtctgt ttttctagac 3900

 accaaggggg agtaagctga gctgtctagc acggattgga gactccctct 3950

 ccctggtggg cctggcaatg acagcatttc tcacagaggc attctggtaa 4000

 atgaagctga aaggggtgtt ttacatctgt aaacggtttc aaacaggtag 4050

 agagaaaaac accacaatta acactgttac tttttgcctt gtctggcatg 4100

 tttgttttaa atgaatacat taatggggtt tttatccttt tgaatgactt 4150

 ttcagacact agacataaat ctcttccctc cagtgtatgc tctgcctttt 4200

 taaccactga catgtaagga ggactactgt ctagcatcag cttatggggt 4250

 cagctggctg tggggataga gtcctgagga atgtggtcac agcaagaagg 4300

 cggggagcag cagagccttg cctttgaatg aggcagcttg tgaggcaagc 4350

 attctggaga gaggtgcttt gaaagtaagg tgcggccttt cacctcttcc 4400

 ttgattactc acacatcttt gcgttctccc ctgccgtcct tcaactgtat 4450

 cttacttttc ttaccagaaa ggaatggagt ctgtttagag acaacttgga 4500

 caacctgtga gtgcatctct tctttccttt agtcttcaca gctaactctg 4550

 gagagcttca aaactagaag gatctactcc gcatgggtgc atgcagaggc 4600

 tcctggatct gggaagcccg ccccctcaca aatgctgagc cgttcttgct 4650

 ctgaaactgc gtgagtcaag gcaaatgcaa aaagccaggt tttggggatg 4700

 tgtcttactg tgcttcaact tcccaaggaa ttgaaagtca acctaactgt 4750

 aacaacaggg tgagaaatga ccaaactgcc cgtgactttt tctgaatgga 4800

 cttcataacc ggaagactta accggtggcc tcatcaccag agcatcgcca 4850

 ggatttctaa tgcactcagt ttccctacat agcagggatt cttagctagg 4900

 tgtccccatg aaccccgtaa agttctacac aaagtcttgc atacaggagc 4950

 ctttacaaga tgattataca gggttgcaga ttgggtgact gaccagactt 5000

 gttggggtcc tgggatgagt tgccccgggc tgcaaattaa gagtacagct 5050

 aagtgcgggg gtggcggtgg agggaacgaa aattgaacct gtctgcctgt 5100

 gctgtgtcgt gtggctttat cagcccgagg aagggcaggt gtattctaat 5150

 ttgcacaaag gtgctgggta gactagtggc agctctcatg tgctgcacat 5200

 aagtggaatc agtatgaata gaagaacttg ctgtataaag gaatttcatg 5250

 gcaacaatgc tggtaagggc aattagcctc gcttaagttg ccttttttac 5300

 acaccaaaac tttttacatg aagggctggt ttcacatgaa tactatactg 5350

 aaatctgtgc cacaccaaaa ctttttacat gaagggctgg tttcacatga 5400

 atactatact gaaatctgtg ctctcaagat ctagcagtga ccagggctgc 5450

 ccggcggggg ctctcctggc aagtcaggaa ggtttctgtt gctaatataa 5500

 catagaaaca cattagtgca ctgggcctct ctgaggtcag catatttgta 5550

 ctcttggaat atttgttttt ttcttcagta acaacagaaa ccccagttgg 5600

 gagtttaaca aataactgac taccactcac tcatgcattt ttatttccaa 5650

 ttaaagcaaa gcactgtgct gtgctcagat aataatagtt tgtaagtaaa 5700

 agtttttagt tttcagtgtt caggttatag aatataactg accataaaaa 5750

 ttacctgcag gtattttctt tttatgaact tgtttttaaa ttaccaagta 5800

 attactggtg tcattttgtt ttatgacaga cacacgtatc taacaaacaa 5850

 acaaacagtg accttctcca tgggtcaagg acttccttac aatttctcct 5900

 gagttaactt ttgtgaaaat aatacctaag gttttctggc ttattgagga 5950

 aatttcctaa caaacaaaca aacaaacaaa cagaagagaa gatcattaac 6000

 cactgtatac tttgtgtata taataggtca gtgtaaagaa atatgatttg 6050

 aggtggtgca tgcaagtaac tagggtttat tctatataat gaatatttat 6100

 agatctgtaa catttgtttc aaaatgctgt ttcattttta taaagtacca 6150

 gtgtttagct gctttttata cattaaatta gcaatttgaa aaactc 6196

<210> 5358
<211> 1080
<212> PRT
<213> Homo sapien

<400> 5358
 Met Pro Ala Lys Gly Arg Tyr Phe Leu Asn Glu Gly Glu Glu Gly
   1               5                  10                  15

 Pro Asp Gln Asp Ala Leu Tyr Glu Lys Tyr Gln Leu Thr Ser Gln
                  20                  25                  30

 His Gly Pro Leu Leu Leu Thr Leu Leu Leu Val Ala Ala Thr Ala
                  35                  40                  45

 Cys Val Ala Leu Ile Ile Ile Ala Phe Ser Gln Gly Asp Pro Ser
                  50                  55                  60

 Arg His Gln Ala Ile Leu Gly Met Ala Phe Leu Val Leu Ala Val
                  65                  70                  75

 Phe Ala Ala Leu Ser Val Leu Met Tyr Val Glu Cys Leu Leu Arg
                  80                  85                  90

 Arg Trp Leu Arg Ala Leu Ala Leu Leu Thr Trp Ala Cys Leu Val
                  95                 100                 105

 Ala Leu Gly Tyr Val Leu Val Phe Asp Ala Trp Thr Lys Ala Ala
                 110                 115                 120

 Cys Ala Trp Glu Gln Val Pro Phe Phe Leu Phe Ile Val Phe Val
                 125                 130                 135

 Val Tyr Thr Leu Leu Pro Phe Ser Met Arg Gly Ala Val Ala Val
                 140                 145                 150

 Gly Ala Val Ser Thr Ala Ser His Leu Leu Val Leu Gly Ser Leu
                 155                 160                 165

 Met Gly Gly Phe Thr Thr Pro Ser Val Arg Val Gly Leu Gln Leu
                 170                 175                 180

 Leu Ala Asn Ala Val Ile Phe Leu Cys Gly Asn Leu Thr Gly Ala
                 185                 190                 195

 Phe His Lys His Gln Met Gln Asp Ala Ser Arg Asp Leu Phe Thr
                 200                 205                 210

 Tyr Thr Val Lys Cys Ile Gln Ile Arg Arg Lys Leu Arg Ile Glu
                 215                 220                 225

 Lys Arg Gln Gln Glu Asn Leu Leu Leu Ser Val Leu Pro Ala His
                 230                 235                 240

 Ile Ser Met Gly Met Lys Leu Ala Ile Ile Glu Arg Leu Lys Glu
                 245                 250                 255

 His Gly Asp Arg Arg Cys Met Pro Asp Asn Asn Phe His Ser Leu
                 260                 265                 270

 Tyr Val Lys Arg His Gln Asn Val Ser Ile Leu Tyr Ala Asp Ile
                 275                 280                 285

 Val Gly Phe Thr Gln Leu Ala Ser Asp Cys Ser Pro Lys Glu Leu
                 290                 295                 300

 Val Val Val Leu Asn Glu Leu Phe Gly Lys Phe Asp Gln Ile Ala
                 305                 310                 315

 Lys Ala Asn Glu Cys Met Arg Ile Lys Ile Leu Gly Asp Cys Tyr
                 320                 325                 330

 Tyr Cys Val Ser Gly Leu Pro Val Ser Leu Pro Thr His Ala Arg
                 335                 340                 345

 Asn Cys Val Lys Met Gly Leu Asp Met Cys Gln Ala Ile Lys Gln
                 350                 355                 360

 Val Arg Glu Ala Thr Gly Val Asp Ile Asn Met Arg Val Gly Ile
                 365                 370                 375

 His Ser Gly Asn Val Leu Cys Gly Val Ile Gly Leu Arg Lys Trp
                 380                 385                 390

 Gln Tyr Asp Val Trp Ser His Asp Val Ser Leu Ala Asn Arg Met
                 395                 400                 405

 Glu Ala Ala Gly Val Pro Gly Arg Val His Ile Thr Glu Ala Thr
                 410                 415                 420

 Leu Lys His Leu Asp Lys Ala Tyr Glu Val Glu Asp Gly His Gly
                 425                 430                 435

 Gln Gln Arg Asp Pro Tyr Leu Lys Glu Met Asn Ile Arg Thr Tyr
                 440                 445                 450

 Leu Val Ile Asp Pro Arg Ser Gln Gln Pro Pro Pro Pro Ser Gln
                 455                 460                 465

 His Leu Pro Arg Pro Lys Gly Asp Ala Ala Leu Lys Met Arg Ala
                 470                 475                 480

 Ser Val Arg Met Thr Arg Tyr Leu Glu Ser Trp Gly Ala Ala Arg
                 485                 490                 495

 Pro Phe Ala His Leu Asn His Arg Glu Ser Val Ser Ser Gly Glu
                 500                 505                 510

 Thr His Val Pro Asn Gly Arg Arg Pro Lys Ser Val Pro Gln Arg
                 515                 520                 525

 His Arg Arg Thr Pro Asp Arg Ser Met Ser Pro Lys Gly Arg Ser
                 530                 535                 540

 Glu Asp Asp Ser Tyr Asp Asp Glu Met Leu Ser Ala Ile Glu Gly
                 545                 550                 555

 Leu Ser Ser Thr Arg Pro Cys Cys Ser Lys Ser Asp Asp Phe Tyr
                 560                 565                 570

 Thr Phe Gly Ser Ile Phe Leu Glu Lys Gly Phe Glu Arg Glu Tyr
                 575                 580                 585

 Arg Leu Ala Pro Ile Pro Arg Ala Arg His Asp Phe Ala Cys Ala
                 590                 595                 600

 Ser Leu Ile Phe Val Cys Ile Leu Leu Val His Val Leu Leu Met
                 605                 610                 615

 Pro Arg Thr Ala Ala Leu Gly Val Ser Phe Gly Leu Val Ala Cys
                 620                 625                 630

 Val Leu Gly Leu Val Leu Gly Leu Cys Phe Ala Thr Lys Phe Ser
                 635                 640                 645

 Arg Cys Cys Pro Ala Arg Gly Thr Leu Cys Thr Ile Ser Glu Arg
                 650                 655                 660

 Val Glu Thr Gln Pro Leu Leu Arg Leu Thr Leu Ala Val Leu Thr
                 665                 670                 675

 Ile Gly Ser Leu Leu Thr Val Ala Ile Ile Asn Leu Pro Leu Met
                 680                 685                 690

 Pro Phe Gln Val Pro Glu Leu Pro Val Gly Asn Glu Thr Gly Leu
                 695                 700                 705

 Leu Ala Ala Ser Ser Lys Thr Arg Ala Leu Cys Glu Pro Leu Pro
                 710                 715                 720

 Tyr Tyr Thr Cys Ser Cys Val Leu Gly Phe Ile Ala Cys Ser Val
                 725                 730                 735

 Phe Leu Arg Met Ser Leu Glu Pro Lys Val Val Leu Leu Thr Val
                 740                 745                 750

 Ala Leu Val Ala Tyr Leu Val Leu Phe Asn Leu Ser Pro Cys Trp
                 755                 760                 765

 Gln Trp Asp Cys Cys Gly Gln Gly Leu Gly Asn Leu Thr Lys Pro
                 770                 775                 780

 Asn Gly Thr Thr Ser Gly Thr Pro Ser Cys Ser Trp Lys Asp Leu
                 785                 790                 795

 Lys Thr Met Thr Asn Phe Tyr Leu Val Leu Phe Tyr Ile Thr Leu
                 800                 805                 810

 Leu Thr Leu Ser Arg Gln Ile Asp Tyr Tyr Cys Arg Leu Asp Cys
                 815                 820                 825

 Leu Trp Lys Lys Lys Phe Lys Lys Glu His Glu Glu Phe Glu Thr
                 830                 835                 840

 Met Glu Asn Val Asn Arg Leu Leu Leu Glu Asn Val Leu Pro Ala
                 845                 850                 855

 His Val Ala Ala His Phe Ile Gly Asp Lys Leu Asn Glu Asp Trp
                 860                 865                 870

 Tyr His Gln Ser Tyr Asp Cys Val Cys Val Met Phe Ala Ser Val
                 875                 880                 885

 Pro Asp Phe Lys Val Phe Tyr Thr Glu Cys Asp Val Asn Lys Glu
                 890                 895                 900

 Gly Leu Glu Cys Leu Arg Leu Leu Asn Glu Ile Ile Ala Asp Phe
                 905                 910                 915

 Asp Glu Leu Leu Leu Lys Pro Lys Phe Ser Gly Val Glu Lys Ile
                 920                 925                 930

 Lys Thr Ile Gly Ser Thr Tyr Met Ala Ala Ala Gly Leu Ser Val
                 935                 940                 945

 Ala Ser Gly His Glu Asn Gln Glu Leu Glu Arg Gln His Ala His
                 950                 955                 960

 Ile Gly Val Met Val Glu Phe Ser Ile Ala Leu Met Ser Lys Leu
                 965                 970                 975

 Asp Gly Ile Asn Arg His Ser Phe Asn Ser Phe Arg Leu Arg Val
                 980                 985                 990

 Gly Ile Asn His Gly Pro Val Ile Ala Gly Val Ile Gly Ala Arg
                 995                1000                1005

 Lys Pro Gln Tyr Asp Ile Trp Gly Asn Thr Val Asn Val Ala Ser
                1010                1015                1020

 Arg Met Glu Ser Thr Gly Glu Leu Gly Lys Ile Gln Val Thr Glu
                1025                1030                1035

 Glu Thr Cys Thr Ile Leu Gln Gly Leu Gly Tyr Ser Cys Glu Cys
                1040                1045                1050

 Arg Gly Leu Ile Asn Val Lys Gly Lys Gly Glu Leu Arg Thr Tyr
                1055                1060                1065

 Phe Val Cys Thr Asp Thr Ala Lys Phe Gln Gly Leu Gly Leu Asn
                1070                1075                1080

<210> 5359
<211> 1630
<212> DNA
<213> Homo sapien

<400> 5359
 agggccgggg tggggcgctg gcgtttccgt tgcttggatc agtctaggtg 50

 cagctgcgga tccttcagcg tctgcatctc ggcgtcgccc cgcgtaccgt 100

 cgcccggctc tccgccgctc tcccgggggt tcggggcact tgggtcccac 150

 agtctggtcc tgcttcacct tcccctgacc tgagtagtcg ccatggcaca 200

 ggttctcaga ggcactgtga ctgacttccc tggatttgat gagcgggctg 250

 atgcagaaac tcttcggaag gctatgaaag gcttgggcac agatgaggag 300

 agcatcctga ctctgttgac atcccgaagt aatgctcagc gccaggaaat 350

 ctctgcagct tttaagactc tgtttggcag ggatcttctg gatgacctga 400

 aatcagaact aactggaaaa tttgaaaaat taattgtggc tctgatgaaa 450

 ccctctcggc tttatgatgc ttatgaactg aaacatgcct tgaagggagc 500

 tggaacaaat gaaaaagtac tgacagaaat tattgcttca aggacacctg 550

 aagaactgag agccatcaaa caagtttatg aagaagaata tggctcaagc 600

 ctggaagatg acgtggtggg ggacacttca gggtactacc agcggatgtt 650

 ggtggttctc cttcaggcta acagagaccc tgatgctgga attgatgaag 700

 ctcaagttga acaagatgct caggctttat ttcaggctgg agaacttaaa 750

 tgggggacag atgaagaaaa gtttatcacc atctttggaa cacgaagtgt 800

 gtctcatttg agaaaggtgt ttgacaagta catgactata tcaggatttc 850

 aaattgagga aaccattgac cgcgagactt ctggcaattt agagcaacta 900

 ctccttgctg ttgtgaaatc tattcgaagt atacctgcct accttgcaga 950

 gaccctctat tatgctatga agggagctgg gacagatgat cataccctca 1000

 tcagagtcat ggtttccagg agtgagattg atctgtttaa catcaggaag 1050

 gagtttagga agaattttgc cacctctctt tattccatga ttaagggaga 1100

 tacatctggg gactataaga aagctcttct gctgctctgt ggagaagatg 1150

 actaacgtgt cacggggaag agctccctgc tgtgtgcctg caccacccca 1200

 ctgccttcct tcagcacctt tagctgcatt tgtatgccag tgcttaacac 1250

 attgccttat tcatactagc atgctcatga ccaacacata cacgtcatag 1300

 aagaaaatag tggtgcttct ttctgatctc tagtggagat ctctttgact 1350

 gctgtagtac taaagtgtac ttaatgttac taagtttaat gcctggccat 1400

 tttccattta tatatatttt ttaagaggct agagtgcttt tagccttttt 1450

 taaaaactcc atttatatta catttgtaac catgatactt taattagaag 1500

 cttagccttg aaattgtgaa ctcttggaaa tgttattagt gaagttcgca 1550

 actaaactaa acctgtaaaa ttatgatgat tgtattcaaa agattaatga 1600

 aaaataaaca tttctgtccc cctgaattat 1630

<210> 5360
<211> 320
<212> PRT
<213> Homo sapien

<400> 5360
 Met Ala Gln Val Leu Arg Gly Thr Val Thr Asp Phe Pro Gly Phe
   1               5                  10                  15

 Asp Glu Arg Ala Asp Ala Glu Thr Leu Arg Lys Ala Met Lys Gly
                  20                  25                  30

 Leu Gly Thr Asp Glu Glu Ser Ile Leu Thr Leu Leu Thr Ser Arg
                  35                  40                  45

 Ser Asn Ala Gln Arg Gln Glu Ile Ser Ala Ala Phe Lys Thr Leu
                  50                  55                  60

 Phe Gly Arg Asp Leu Leu Asp Asp Leu Lys Ser Glu Leu Thr Gly
                  65                  70                  75

 Lys Phe Glu Lys Leu Ile Val Ala Leu Met Lys Pro Ser Arg Leu
                  80                  85                  90

 Tyr Asp Ala Tyr Glu Leu Lys His Ala Leu Lys Gly Ala Gly Thr
                  95                 100                 105

 Asn Glu Lys Val Leu Thr Glu Ile Ile Ala Ser Arg Thr Pro Glu
                 110                 115                 120

 Glu Leu Arg Ala Ile Lys Gln Val Tyr Glu Glu Glu Tyr Gly Ser
                 125                 130                 135

 Ser Leu Glu Asp Asp Val Val Gly Asp Thr Ser Gly Tyr Tyr Gln
                 140                 145                 150

 Arg Met Leu Val Val Leu Leu Gln Ala Asn Arg Asp Pro Asp Ala
                 155                 160                 165

 Gly Ile Asp Glu Ala Gln Val Glu Gln Asp Ala Gln Ala Leu Phe
                 170                 175                 180

 Gln Ala Gly Glu Leu Lys Trp Gly Thr Asp Glu Glu Lys Phe Ile
                 185                 190                 195

 Thr Ile Phe Gly Thr Arg Ser Val Ser His Leu Arg Lys Val Phe
                 200                 205                 210

 Asp Lys Tyr Met Thr Ile Ser Gly Phe Gln Ile Glu Glu Thr Ile
                 215                 220                 225

 Asp Arg Glu Thr Ser Gly Asn Leu Glu Gln Leu Leu Leu Ala Val
                 230                 235                 240

 Val Lys Ser Ile Arg Ser Ile Pro Ala Tyr Leu Ala Glu Thr Leu
                 245                 250                 255

 Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp His Thr Leu Ile
                 260                 265                 270

 Arg Val Met Val Ser Arg Ser Glu Ile Asp Leu Phe Asn Ile Arg
                 275                 280                 285

 Lys Glu Phe Arg Lys Asn Phe Ala Thr Ser Leu Tyr Ser Met Ile
                 290                 295                 300

 Lys Gly Asp Thr Ser Gly Asp Tyr Lys Lys Ala Leu Leu Leu Leu
                 305                 310                 315

 Cys Gly Glu Asp Asp
                 320

<210> 5361
<211> 3702
<212> DNA
<213> Homo sapien

<400> 5361
 gtttgttagg gagtcgtgtg cgtgccttgg tcgcttctgt agctccgagg 50

 gcaggttgcg gaagaaagcc caggcggtct gtggcccaga ggaaaggcct 100

 gcagcaggac gaggacctga gccaggaatg caggatggcg gcggtgaaga 150

 aggaaggggg tgctctgagt gaagccatgt ccctggaggg agatgaatgg 200

 gaactgagta aagaaaatgt acaaccttta aggcaagggc ggatcatgtc 250

 cacgcttcag ggagcactgg cacaagaatc tgcctgtaac aatactcttc 300

 agcagcagaa acgggcattt gaatatgaaa ttcgatttta cactggaaat 350

 gaccctctgg atgtttggga taggtatatc agctggacag agcagaacta 400

 tcctcaaggt gggaaggaga gtaatatgtc aacgttatta gaaagagctg 450

 tagaagcact acaaggagaa aaacgatatt atagtgatcc tcgatttctc 500

 aatctctggc ttaaattagg gcgtttatgc aatgagcctt tggatatgta 550

 cagttacttg cacaaccaag ggattggtgt ttcacttgct cagttctata 600

 tctcatgggc agaagaatat gaagctagag aaaactttag gaaagcagat 650

 gcgatatttc aggaagggat tcaacagaag gctgaaccac tagaaagact 700

 acagtcccag caccgacaat tccaagctcg agtgtctcgg caaactctgt 750

 tggcacttga gaaagaagaa gaggaggaag tttttgagtc ttctgtacca 800

 caacgaagca cactagctga actaaagagc aaagggaaaa agacagcaag 850

 agctccaatc atccgtgtag gaggtgctct caaggctcca agccagaaca 900

 gaggactcca aaatccattt cctcaacaga tgcaaaataa tagtagaatt 950

 actgtttttg atgaaaatgc tgatgaggct tctacagcag agttgtctaa 1000

 gcctacagtc cagccatgga tagcaccccc catgcccagg gccaaagaga 1050

 atgagctgca agcaggccct tggaacacag gcaggtcctt ggaacacagg 1100

 cctcgtggca atacagcttc actgatagct gtacccgctg tgcttcccag 1150

 tttcactcca tatgtggaag agactgcaca acagccagtt atgacaccat 1200

 gtaaaattga acctagtata aaccacatcc taagcaccag aaagcctgga 1250

 aaggaagaag gagattctct acaaagggtt cagagccatc agcaagcgtc 1300

 tgaggagaag aaagagaaga tgatgtattg taaggagaag atttatgcag 1350

 gagtagggga attctccttt gaagaaattc gggctgaagt tttccggaag 1400

 aaattaaaag agcaaaggga agccgagcta ttgaccagtg cagagaagag 1450

 agcagaaatg cagaaacaga ttgaagagat ggagaagaag ctaaaagaaa 1500

 tccaaactac tcagcaagaa agaacaggtg atcagcaaga agagacgatg 1550

 cctacaaagg agacaactaa actgcaaatt gcttccgagt ctcagaaaat 1600

 accaggaatg actctatcca gttctgtttg tcaagtaaac tgttgtgcca 1650

 gagaaacttc acttgcggag aacatttggc aggaacaacc tcattctaaa 1700

 ggtcccagtg tacctttctc catttttgat gagtttcttc tttcagaaaa 1750

 gaagaataaa agtcctcctg cagatccccc acgagtttta gctcaacgaa 1800

 gaccccttgc agttctcaaa acctcagaaa gcatcacctc aaatgaagat 1850

 gtgtctccag atgtttgtga tgaatttaca ggaattgaac ccttgagcga 1900

 ggatgccatt atcacaggct tcagaaatgt aacaatttgt cctaacccag 1950

 aagacacttg tgactttgcc agagcagctc gttttgtatc cactcctttt 2000

 catgagataa tgtccttgaa ggatctccct tctgatcctg agagactgtt 2050

 accggaagaa gatctagatg taaagacctc tgaggaccag cagacagctt 2100

 gtggcactat ctacagtcag actctcagca tcaagaagct gagcccaatt 2150

 attgaagaca gtcgtgaagc cacacactcc tctggcttct ctggttcttc 2200

 tgcctcggtt gcaagcacct cctccatcaa atgtcttcaa attcctgaga 2250

 aactagaact tactaatgag acttcagaaa accctactca gtcaccatgg 2300

 tgttcacagt atcgcagaca gctactgaag tccctaccag agttaagtgc 2350

 ctctgcagag ttgtgtatag aagacagacc aatgcctaag ttggaaattg 2400

 agaaggaaat tgaattaggt aatgaggatt actgcattaa acgagaatac 2450

 ctaatatgtg aagattacaa gttattctgg gtggcgccaa gaaactctgc 2500

 agaattaaca gtaataaagg tatcttctca acctgtccca tgggactttt 2550

 atatcaacct caagttaaag gaacgtttaa atgaagattt tgatcatttt 2600

 tgcagctgtt atcaatatca agatggctgt attgtttggc accaatatat 2650

 aaactgcttc acccttcagg atcttctcca acacagtgaa tatattaccc 2700

 atgaaataac agtgttgatt atttataacc ttttgacaat agtggagatg 2750

 ctacacaaag cagaaatagt ccatggtgac ttgagtccaa ggtgtctgat 2800

 tctcagaaac agaatccacg atccctatga ttgtaacaag aacaatcaag 2850

 ctttgaagat agtggacttt tcctacagtg ttgaccttag ggtgcagctg 2900

 gatgttttta ccctcagcgg ctttcggact gtacagatcc tggaaggaca 2950

 aaagatcctg gctaactgtt cttctcccta ccaggtagac ctgtttggta 3000

 tagcagattt agcacattta ctattgttca aggaacacct acaggtcttc 3050

 tgggatgggt ccttctggaa acttagccaa aatatttctg agctaaaaga 3100

 tggtgaattg tggaataaat tctttgtgcg gattctgaat gccaatgatg 3150

 aggccacagt gtctgttctt ggggagcttg cagcagaaat gaatggggtt 3200

 tttgacacta cattccaaag tcacctgaac aaagccttat ggaaggtagg 3250

 gaagttaact agtcctgggg ctttgctctt tcagtgagct aggcaatcaa 3300

 gtctcacaga ttgctgcctc agagcaatgg ttgtattgtg gaacactgaa 3350

 actgtatgtg ctgtaattta atttaggaca catttagatg cactaccatt 3400

 gctgttctac tttttggtac aggtatattt tgacgtcact gatatttttt 3450

 atacagtgat atacttactc atggccttgt ctaacttttg tgaagaacta 3500

 ttttattcta aacagactca ttacaaatgg ttaccttgtt atttaaccca 3550

 tttgtctcta cttttccctg tacttttccc atttgtaatt tgtaaaatgt 3600

 tctcttatga tcaccatgta ttttgtaaat aataaaatag tatctgttaa 3650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3700

 aa 3702

<210> 5362
<211> 1050
<212> PRT
<213> Homo sapien

<400> 5362
 Met Ala Ala Val Lys Lys Glu Gly Gly Ala Leu Ser Glu Ala Met
   1               5                  10                  15

 Ser Leu Glu Gly Asp Glu Trp Glu Leu Ser Lys Glu Asn Val Gln
                  20                  25                  30

 Pro Leu Arg Gln Gly Arg Ile Met Ser Thr Leu Gln Gly Ala Leu
                  35                  40                  45

 Ala Gln Glu Ser Ala Cys Asn Asn Thr Leu Gln Gln Gln Lys Arg
                  50                  55                  60

 Ala Phe Glu Tyr Glu Ile Arg Phe Tyr Thr Gly Asn Asp Pro Leu
                  65                  70                  75

 Asp Val Trp Asp Arg Tyr Ile Ser Trp Thr Glu Gln Asn Tyr Pro
                  80                  85                  90

 Gln Gly Gly Lys Glu Ser Asn Met Ser Thr Leu Leu Glu Arg Ala
                  95                 100                 105

 Val Glu Ala Leu Gln Gly Glu Lys Arg Tyr Tyr Ser Asp Pro Arg
                 110                 115                 120

 Phe Leu Asn Leu Trp Leu Lys Leu Gly Arg Leu Cys Asn Glu Pro
                 125                 130                 135

 Leu Asp Met Tyr Ser Tyr Leu His Asn Gln Gly Ile Gly Val Ser
                 140                 145                 150

 Leu Ala Gln Phe Tyr Ile Ser Trp Ala Glu Glu Tyr Glu Ala Arg
                 155                 160                 165

 Glu Asn Phe Arg Lys Ala Asp Ala Ile Phe Gln Glu Gly Ile Gln
                 170                 175                 180

 Gln Lys Ala Glu Pro Leu Glu Arg Leu Gln Ser Gln His Arg Gln
                 185                 190                 195

 Phe Gln Ala Arg Val Ser Arg Gln Thr Leu Leu Ala Leu Glu Lys
                 200                 205                 210

 Glu Glu Glu Glu Glu Val Phe Glu Ser Ser Val Pro Gln Arg Ser
                 215                 220                 225

 Thr Leu Ala Glu Leu Lys Ser Lys Gly Lys Lys Thr Ala Arg Ala
                 230                 235                 240

 Pro Ile Ile Arg Val Gly Gly Ala Leu Lys Ala Pro Ser Gln Asn
                 245                 250                 255

 Arg Gly Leu Gln Asn Pro Phe Pro Gln Gln Met Gln Asn Asn Ser
                 260                 265                 270

 Arg Ile Thr Val Phe Asp Glu Asn Ala Asp Glu Ala Ser Thr Ala
                 275                 280                 285

 Glu Leu Ser Lys Pro Thr Val Gln Pro Trp Ile Ala Pro Pro Met
                 290                 295                 300

 Pro Arg Ala Lys Glu Asn Glu Leu Gln Ala Gly Pro Trp Asn Thr
                 305                 310                 315

 Gly Arg Ser Leu Glu His Arg Pro Arg Gly Asn Thr Ala Ser Leu
                 320                 325                 330

 Ile Ala Val Pro Ala Val Leu Pro Ser Phe Thr Pro Tyr Val Glu
                 335                 340                 345

 Glu Thr Ala Gln Gln Pro Val Met Thr Pro Cys Lys Ile Glu Pro
                 350                 355                 360

 Ser Ile Asn His Ile Leu Ser Thr Arg Lys Pro Gly Lys Glu Glu
                 365                 370                 375

 Gly Asp Ser Leu Gln Arg Val Gln Ser His Gln Gln Ala Ser Glu
                 380                 385                 390

 Glu Lys Lys Glu Lys Met Met Tyr Cys Lys Glu Lys Ile Tyr Ala
                 395                 400                 405

 Gly Val Gly Glu Phe Ser Phe Glu Glu Ile Arg Ala Glu Val Phe
                 410                 415                 420

 Arg Lys Lys Leu Lys Glu Gln Arg Glu Ala Glu Leu Leu Thr Ser
                 425                 430                 435

 Ala Glu Lys Arg Ala Glu Met Gln Lys Gln Ile Glu Glu Met Glu
                 440                 445                 450

 Lys Lys Leu Lys Glu Ile Gln Thr Thr Gln Gln Glu Arg Thr Gly
                 455                 460                 465

 Asp Gln Gln Glu Glu Thr Met Pro Thr Lys Glu Thr Thr Lys Leu
                 470                 475                 480

 Gln Ile Ala Ser Glu Ser Gln Lys Ile Pro Gly Met Thr Leu Ser
                 485                 490                 495

 Ser Ser Val Cys Gln Val Asn Cys Cys Ala Arg Glu Thr Ser Leu
                 500                 505                 510

 Ala Glu Asn Ile Trp Gln Glu Gln Pro His Ser Lys Gly Pro Ser
                 515                 520                 525

 Val Pro Phe Ser Ile Phe Asp Glu Phe Leu Leu Ser Glu Lys Lys
                 530                 535                 540

 Asn Lys Ser Pro Pro Ala Asp Pro Pro Arg Val Leu Ala Gln Arg
                 545                 550                 555

 Arg Pro Leu Ala Val Leu Lys Thr Ser Glu Ser Ile Thr Ser Asn
                 560                 565                 570

 Glu Asp Val Ser Pro Asp Val Cys Asp Glu Phe Thr Gly Ile Glu
                 575                 580                 585

 Pro Leu Ser Glu Asp Ala Ile Ile Thr Gly Phe Arg Asn Val Thr
                 590                 595                 600

 Ile Cys Pro Asn Pro Glu Asp Thr Cys Asp Phe Ala Arg Ala Ala
                 605                 610                 615

 Arg Phe Val Ser Thr Pro Phe His Glu Ile Met Ser Leu Lys Asp
                 620                 625                 630

 Leu Pro Ser Asp Pro Glu Arg Leu Leu Pro Glu Glu Asp Leu Asp
                 635                 640                 645

 Val Lys Thr Ser Glu Asp Gln Gln Thr Ala Cys Gly Thr Ile Tyr
                 650                 655                 660

 Ser Gln Thr Leu Ser Ile Lys Lys Leu Ser Pro Ile Ile Glu Asp
                 665                 670                 675

 Ser Arg Glu Ala Thr His Ser Ser Gly Phe Ser Gly Ser Ser Ala
                 680                 685                 690

 Ser Val Ala Ser Thr Ser Ser Ile Lys Cys Leu Gln Ile Pro Glu
                 695                 700                 705

 Lys Leu Glu Leu Thr Asn Glu Thr Ser Glu Asn Pro Thr Gln Ser
                 710                 715                 720

 Pro Trp Cys Ser Gln Tyr Arg Arg Gln Leu Leu Lys Ser Leu Pro
                 725                 730                 735

 Glu Leu Ser Ala Ser Ala Glu Leu Cys Ile Glu Asp Arg Pro Met
                 740                 745                 750

 Pro Lys Leu Glu Ile Glu Lys Glu Ile Glu Leu Gly Asn Glu Asp
                 755                 760                 765

 Tyr Cys Ile Lys Arg Glu Tyr Leu Ile Cys Glu Asp Tyr Lys Leu
                 770                 775                 780

 Phe Trp Val Ala Pro Arg Asn Ser Ala Glu Leu Thr Val Ile Lys
                 785                 790                 795

 Val Ser Ser Gln Pro Val Pro Trp Asp Phe Tyr Ile Asn Leu Lys
                 800                 805                 810

 Leu Lys Glu Arg Leu Asn Glu Asp Phe Asp His Phe Cys Ser Cys
                 815                 820                 825

 Tyr Gln Tyr Gln Asp Gly Cys Ile Val Trp His Gln Tyr Ile Asn
                 830                 835                 840

 Cys Phe Thr Leu Gln Asp Leu Leu Gln His Ser Glu Tyr Ile Thr
                 845                 850                 855

 His Glu Ile Thr Val Leu Ile Ile Tyr Asn Leu Leu Thr Ile Val
                 860                 865                 870

 Glu Met Leu His Lys Ala Glu Ile Val His Gly Asp Leu Ser Pro
                 875                 880                 885

 Arg Cys Leu Ile Leu Arg Asn Arg Ile His Asp Pro Tyr Asp Cys
                 890                 895                 900

 Asn Lys Asn Asn Gln Ala Leu Lys Ile Val Asp Phe Ser Tyr Ser
                 905                 910                 915

 Val Asp Leu Arg Val Gln Leu Asp Val Phe Thr Leu Ser Gly Phe
                 920                 925                 930

 Arg Thr Val Gln Ile Leu Glu Gly Gln Lys Ile Leu Ala Asn Cys
                 935                 940                 945

 Ser Ser Pro Tyr Gln Val Asp Leu Phe Gly Ile Ala Asp Leu Ala
                 950                 955                 960

 His Leu Leu Leu Phe Lys Glu His Leu Gln Val Phe Trp Asp Gly
                 965                 970                 975

 Ser Phe Trp Lys Leu Ser Gln Asn Ile Ser Glu Leu Lys Asp Gly
                 980                 985                 990

 Glu Leu Trp Asn Lys Phe Phe Val Arg Ile Leu Asn Ala Asn Asp
                 995                1000                1005

 Glu Ala Thr Val Ser Val Leu Gly Glu Leu Ala Ala Glu Met Asn
                1010                1015                1020

 Gly Val Phe Asp Thr Thr Phe Gln Ser His Leu Asn Lys Ala Leu
                1025                1030                1035

 Trp Lys Val Gly Lys Leu Thr Ser Pro Gly Ala Leu Leu Phe Gln
                1040                1045                1050

<210> 5363
<211> 1343
<212> DNA
<213> Homo sapien

<400> 5363
 gctctttcca acgctgtaaa aaggacagag gctgttccct atggcagaag 50

 gcaaccacag aaaaaagcca cttaaggtgt tggaatccct gggcaaagat 100

 ttcctcactg gtgttttgga taacttggtg gaacaaaatg tactgaactg 150

 gaaggaagag gaaaaaaaga aatattacga tgctaaaact gaagacaaag 200

 ttcgggtcat ggcagactct atgcaagaga agcaacgtat ggcaggacaa 250

 atgcttcttc aaaccttttt taacatagac caaatatccc ccaataaaaa 300

 aggtgataaa ttgggtcaca gaggcagaaa tcacaattta tgttctgcaa 350

 tatcctgcag ctcatccgaa tatggaggct ggaccacctg agtcaggaga 400

 atctacagat gccctcaagc tttgtcctca tgaagaattc ctgagactat 450

 gtaaagaaag agctgaagag atctatccaa taaaggagag aaacaaccgc 500

 acacgcctgg ctctcatcat atgcaataca gagtttgacc atctgcctcc 550

 gaggaatgga gctgactttg acatcacagg gatgaaggag ctacttgagg 600

 gtctggacta tagtgtagat gtagaagaga atctgacagc cagggatatg 650

 gagtcagcgc tgagggcatt tgctaccaga ccagagcaca agtcctctga 700

 cagcacattc ttggtactca tgtctcatgg catcctggag ggaatctgcg 750

 gaactgtgca tgatgagaaa aaaccagatg tgctgcttta tgacaccatc 800

 ttccagatat tcaacaaccg caactgcctc agtctgaagg acaaacccaa 850

 ggtcatcatt gtccaggcct gcagaggtgc aaaccgtggg gaactgtggg 900

 tcagagactc tccagcatcc ttggaagtgg cctcttcaca gtcatctgag 950

 aacctggagg aagatgctgt ttacaagacc cacgtggaga aggacttcat 1000

 tgctttctgc tcttcaacgc cacacaacgt gtcctggaga gacagcacaa 1050

 tgggctctat cttcatcaca caactcatca catgcttcca gaaatattct 1100

 tggtgctgcc acctagagga agtatttcgg aaggtacagc aatcatttga 1150

 aactccaagg gccaaagctc aaatgcccac catagaacga ctgtccatga 1200

 caagatattt ctacctcttt cctggcaatt gaaaatggaa gccacaagca 1250

 gcccagccct ccttaatcaa cttcaaggag caccttcatt agtacagctt 1300

 gcatatttaa cattttgtat ttcaataaaa gtgaagacaa acg 1343

<210> 5364
<211> 286
<212> PRT
<213> Homo sapien

<400> 5364
 Met Glu Ala Gly Pro Pro Glu Ser Gly Glu Ser Thr Asp Ala Leu
   1               5                  10                  15

 Lys Leu Cys Pro His Glu Glu Phe Leu Arg Leu Cys Lys Glu Arg
                  20                  25                  30

 Ala Glu Glu Ile Tyr Pro Ile Lys Glu Arg Asn Asn Arg Thr Arg
                  35                  40                  45

 Leu Ala Leu Ile Ile Cys Asn Thr Glu Phe Asp His Leu Pro Pro
                  50                  55                  60

 Arg Asn Gly Ala Asp Phe Asp Ile Thr Gly Met Lys Glu Leu Leu
                  65                  70                  75

 Glu Gly Leu Asp Tyr Ser Val Asp Val Glu Glu Asn Leu Thr Ala
                  80                  85                  90

 Arg Asp Met Glu Ser Ala Leu Arg Ala Phe Ala Thr Arg Pro Glu
                  95                 100                 105

 His Lys Ser Ser Asp Ser Thr Phe Leu Val Leu Met Ser His Gly
                 110                 115                 120

 Ile Leu Glu Gly Ile Cys Gly Thr Val His Asp Glu Lys Lys Pro
                 125                 130                 135

 Asp Val Leu Leu Tyr Asp Thr Ile Phe Gln Ile Phe Asn Asn Arg
                 140                 145                 150

 Asn Cys Leu Ser Leu Lys Asp Lys Pro Lys Val Ile Ile Val Gln
                 155                 160                 165

 Ala Cys Arg Gly Ala Asn Arg Gly Glu Leu Trp Val Arg Asp Ser
                 170                 175                 180

 Pro Ala Ser Leu Glu Val Ala Ser Ser Gln Ser Ser Glu Asn Leu
                 185                 190                 195

 Glu Glu Asp Ala Val Tyr Lys Thr His Val Glu Lys Asp Phe Ile
                 200                 205                 210

 Ala Phe Cys Ser Ser Thr Pro His Asn Val Ser Trp Arg Asp Ser
                 215                 220                 225

 Thr Met Gly Ser Ile Phe Ile Thr Gln Leu Ile Thr Cys Phe Gln
                 230                 235                 240

 Lys Tyr Ser Trp Cys Cys His Leu Glu Glu Val Phe Arg Lys Val
                 245                 250                 255

 Gln Gln Ser Phe Glu Thr Pro Arg Ala Lys Ala Gln Met Pro Thr
                 260                 265                 270

 Ile Glu Arg Leu Ser Met Thr Arg Tyr Phe Tyr Leu Phe Pro Gly
                 275                 280                 285

 Asn


<210> 5365
<211> 1682
<212> DNA
<213> Homo sapien

<400> 5365
 cggcagccag cctattcttt ggccgggtcg gtgcgagtgg tcggctgggc 50

 agagtgcacg ctgcttggcg ccgcaggctg atcccgccgt ccactcccgg 100

 gagcagtgat gttgggcaac tctgcgccgg ggcctgcgac ccgcgaggcg 150

 ggctcggcgc tgctagcatt gcagcagacg gcgctccaag aggaccagga 200

 gaatatcaac ccggaaaagg cagcgcccgt ccaacaaccg cggacccggg 250

 ccgcgctggc ggtactgaag tccgggaacc cgcggggtct agcgcagcag 300

 cagaggccga agacgagacg ggttgcaccc cttaaggatc ttcctgtaaa 350

 tgatgagcat gtcaccgttc ctccttggaa agcaaacagt aaacagcctg 400

 cgttcaccat tcatgtggat gaagcagaaa aagaagctca gaagaagcca 450

 gctgaatctc aaaaaataga gcgtgaagat gccctggctt ttaattcagc 500

 cattagttta cctggaccca gaaaaccatt ggtccctctt gattatccaa 550

 tggatggtag ttttgagtca ccacatacta tggacatgtc aattgtatta 600

 gaagatgaaa agccagtgag tgttaatgaa gtaccagact accatgagga 650

 tattcacaca taccttaggg aaatggaggt taaatgtaaa cctaaagtgg 700

 gttacatgaa gaaacagcca gacatcacta acagtatgag agctatcctc 750

 gtggactggt tagttgaagt aggagaagaa tataaactac agaatgagac 800

 cctgcatttg gctgtgaact acattgatag gttcctgtct tccatgtcag 850

 tgctgagagg aaaacttcag cttgtgggca ctgctgctat gctgttagcc 900

 tcaaagtttg aagaaatata ccccccagaa gtagcagagt ttgtgtacat 950

 tacagatgat acctacacca agaaacaagt tctgagaatg gagcatctag 1000

 ttttgaaagt ccttactttt gacttagctg ctccaacagt aaatcagttt 1050

 cttacccaat actttctgca tcagcagcct gcaaactgca aagttgaaag 1100

 tttagcaatg tttttgggag aattaagttt gatagatgct gacccatacc 1150

 tcaagtattt gccatcagtt attgctggag ctgcctttca tttagcactc 1200

 tacacagtca cgggacaaag ctggcctgaa tcattaatac gaaagactgg 1250

 atataccctg gaaagtctta agccttgtct catggacctt caccagacct 1300

 acctcaaagc accacagcat gcacaacagt caataagaga aaagtacaaa 1350

 aattcaaagt atcatggtgt ttctctcctc aacccaccag agacactaaa 1400

 tctgtaacaa tgaaagactg cctttgtttt ctaagatgta aatcactcaa 1450

 agtatatggt gtacagtttt taacttaggt tttaatttta caatcatttc 1500

 tgaatacaga agttgtggcc aagtacaaat tatggtatct attacttttt 1550

 aaatggtttt aatttgtata tcttttgtat atgtatctgt cttagatatt 1600

 tggctaattt taagtggttt tgttaaagta ttaatgatgc cagctgtcag 1650

 gataataaat tgatttggaa aacttaaaaa aa 1682

<210> 5366
<211> 432
<212> PRT
<213> Homo sapien

<400> 5366
 Met Leu Gly Asn Ser Ala Pro Gly Pro Ala Thr Arg Glu Ala Gly
   1               5                  10                  15

 Ser Ala Leu Leu Ala Leu Gln Gln Thr Ala Leu Gln Glu Asp Gln
                  20                  25                  30

 Glu Asn Ile Asn Pro Glu Lys Ala Ala Pro Val Gln Gln Pro Arg
                  35                  40                  45

 Thr Arg Ala Ala Leu Ala Val Leu Lys Ser Gly Asn Pro Arg Gly
                  50                  55                  60

 Leu Ala Gln Gln Gln Arg Pro Lys Thr Arg Arg Val Ala Pro Leu
                  65                  70                  75

 Lys Asp Leu Pro Val Asn Asp Glu His Val Thr Val Pro Pro Trp
                  80                  85                  90

 Lys Ala Asn Ser Lys Gln Pro Ala Phe Thr Ile His Val Asp Glu
                  95                 100                 105

 Ala Glu Lys Glu Ala Gln Lys Lys Pro Ala Glu Ser Gln Lys Ile
                 110                 115                 120

 Glu Arg Glu Asp Ala Leu Ala Phe Asn Ser Ala Ile Ser Leu Pro
                 125                 130                 135

 Gly Pro Arg Lys Pro Leu Val Pro Leu Asp Tyr Pro Met Asp Gly
                 140                 145                 150

 Ser Phe Glu Ser Pro His Thr Met Asp Met Ser Ile Val Leu Glu
                 155                 160                 165

 Asp Glu Lys Pro Val Ser Val Asn Glu Val Pro Asp Tyr His Glu
                 170                 175                 180

 Asp Ile His Thr Tyr Leu Arg Glu Met Glu Val Lys Cys Lys Pro
                 185                 190                 195

 Lys Val Gly Tyr Met Lys Lys Gln Pro Asp Ile Thr Asn Ser Met
                 200                 205                 210

 Arg Ala Ile Leu Val Asp Trp Leu Val Glu Val Gly Glu Glu Tyr
                 215                 220                 225

 Lys Leu Gln Asn Glu Thr Leu His Leu Ala Val Asn Tyr Ile Asp
                 230                 235                 240

 Arg Phe Leu Ser Ser Met Ser Val Leu Arg Gly Lys Leu Gln Leu
                 245                 250                 255

 Val Gly Thr Ala Ala Met Leu Leu Ala Ser Lys Phe Glu Glu Ile
                 260                 265                 270

 Tyr Pro Pro Glu Val Ala Glu Phe Val Tyr Ile Thr Asp Asp Thr
                 275                 280                 285

 Tyr Thr Lys Lys Gln Val Leu Arg Met Glu His Leu Val Leu Lys
                 290                 295                 300

 Val Leu Thr Phe Asp Leu Ala Ala Pro Thr Val Asn Gln Phe Leu
                 305                 310                 315

 Thr Gln Tyr Phe Leu His Gln Gln Pro Ala Asn Cys Lys Val Glu
                 320                 325                 330

 Ser Leu Ala Met Phe Leu Gly Glu Leu Ser Leu Ile Asp Ala Asp
                 335                 340                 345

 Pro Tyr Leu Lys Tyr Leu Pro Ser Val Ile Ala Gly Ala Ala Phe
                 350                 355                 360

 His Leu Ala Leu Tyr Thr Val Thr Gly Gln Ser Trp Pro Glu Ser
                 365                 370                 375

 Leu Ile Arg Lys Thr Gly Tyr Thr Leu Glu Ser Leu Lys Pro Cys
                 380                 385                 390

 Leu Met Asp Leu His Gln Thr Tyr Leu Lys Ala Pro Gln His Ala
                 395                 400                 405

 Gln Gln Ser Ile Arg Glu Lys Tyr Lys Asn Ser Lys Tyr His Gly
                 410                 415                 420

 Val Ser Leu Leu Asn Pro Pro Glu Thr Leu Asn Leu
                 425                 430

<210> 5367
<211> 2156
<212> DNA
<213> Homo sapien

<400> 5367
 ggcacgagcc cagaaacaaa gacttcacgg acaaagtccc ttggaaccag 50

 agagaagccg ggatggaaac tccaaacacc acagaggact atgacacgac 100

 cacagagttt gactatgggg atgcaactcc gtgccagaag gtgaacgaga 150

 gggcctttgg ggcccaactg ctgccccctc tgtactcctt ggtatttgtc 200

 attggcctgg ttggaaacat cctggtggtc ctggtccttg tgcaatacaa 250

 gaggctaaaa aacatgacca gcatctacct cctgaacctg gccatttctg 300

 acctgctctt cctgttcacg cttcccttct ggatcgacta caagttgaag 350

 gatgactggg tttttggtga tgccatgtgt aagatcctct ctgggtttta 400

 ttacacaggc ttgtacagcg agatcttttt catcatcctg ctgacgattg 450

 acaggtacct ggccatcgtc cacgccgtgt ttgccttgcg ggcacggacc 500

 gtcacttttg gtgtcatcac cagcatcatc atttgggccc tggccatctt 550

 ggcttccatg ccaggcttat acttttccaa gacccaatgg gaattcactc 600

 accacacctg cagccttcac tttcctcacg aaagcctacg agagtggaag 650

 ctgtttcagg ctctgaaact gaacctcttt gggctggtat tgcctttgtt 700

 ggtcatgatc atctgctaca cagggattat aaagattctg ctaagacgac 750

 caaatgagaa gaaatccaaa gctgtccgtt tgatttttgt catcatgatc 800

 atcttttttc tcttttggac cccctacaat ttgactatac ttatttctgt 850

 tttccaagac ttcctgttca cccatgagtg tgagcagagc agacatttgg 900

 acctggctgt gcaagtgacg gaggtgatcg cctacacgca ctgctgtgtc 950

 aacccagtga tctacgcctt cgttggtgag aggttccgga agtacctgcg 1000

 gcagttgttc cacaggcgtg tggctgtgca cctggttaaa tggctcccct 1050

 tcctctccgt ggacaggctg gagagggtca gctccacatc tccctccaca 1100

 ggggagcatg aactctctgc tgggttctga ctcagaccat aggaggccaa 1150

 cccaaaataa gcaggcgtga cctgccaggc acactgagcc agcagcctgg 1200

 ctctcccagc caggttctga ctcttggcac agcatggagt cacagccact 1250

 tgggatagag agggaatgta atggtggcct ggggcttctg aggcttctgg 1300

 ggcttcagtc ttttccatga acttctcccc tggtagaaag aagatgaatg 1350

 agcaaaacca aatattccag agactgggac taagtgtacc agagaagggc 1400

 ttggactcaa gcaagatttc agatttgtga ccattagcat ttgtcaacaa 1450

 agtcacccac ttcccactat tgcttgcaca aaccaattaa acccagtagt 1500

 ggtgactgtg ggctccattc aaagtgagct cctaagccat gggagacact 1550

 gatgtatgag gaatttctgt tcttccatca cctccccccc cccgccaccc 1600

 tcccactgcc aagaacttgg aaatagtgat ttccacagtg actccactct 1650

 gagtcccaga gccaatcagt agccagcatc tgcctcccct tcactcccac 1700

 cgcaggattt gggctcttgg aatcctgggg aacatagaac tcatgacgga 1750

 agagttgaga cctaacgaga aatagaaatg ggggaactac tgctggcagt 1800

 ggaactaaga aagcccttag gaagaatttt tatatccact aaaatcaaac 1850

 aattcaggga gtgggctaag cacgggccat atgaataaca tggtgtgctt 1900

 cttaaaatag ccataaaggg gagggactca tcatttccat ttacccttct 1950

 tttctgacta tttttcagaa tctctcttct tttcaagttg ggtgatatgt 2000

 tggtagattc taatggcttt attgcagcga ttaataacag gcaaaaggaa 2050

 gcagggttgg tttcccttct ttttgttctt catctaagcc ttctggtttt 2100

 atgggtcaga gttccgactg ccatcttgga cttgtcagca aaaaaaaaaa 2150

 aaaaaa 2156

<210> 5368
<211> 355
<212> PRT
<213> Homo sapien

<400> 5368
 Met Glu Thr Pro Asn Thr Thr Glu Asp Tyr Asp Thr Thr Thr Glu
   1               5                  10                  15

 Phe Asp Tyr Gly Asp Ala Thr Pro Cys Gln Lys Val Asn Glu Arg
                  20                  25                  30

 Ala Phe Gly Ala Gln Leu Leu Pro Pro Leu Tyr Ser Leu Val Phe
                  35                  40                  45

 Val Ile Gly Leu Val Gly Asn Ile Leu Val Val Leu Val Leu Val
                  50                  55                  60

 Gln Tyr Lys Arg Leu Lys Asn Met Thr Ser Ile Tyr Leu Leu Asn
                  65                  70                  75

 Leu Ala Ile Ser Asp Leu Leu Phe Leu Phe Thr Leu Pro Phe Trp
                  80                  85                  90

 Ile Asp Tyr Lys Leu Lys Asp Asp Trp Val Phe Gly Asp Ala Met
                  95                 100                 105

 Cys Lys Ile Leu Ser Gly Phe Tyr Tyr Thr Gly Leu Tyr Ser Glu
                 110                 115                 120

 Ile Phe Phe Ile Ile Leu Leu Thr Ile Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val His Ala Val Phe Ala Leu Arg Ala Arg Thr Val Thr Phe Gly
                 140                 145                 150

 Val Ile Thr Ser Ile Ile Ile Trp Ala Leu Ala Ile Leu Ala Ser
                 155                 160                 165

 Met Pro Gly Leu Tyr Phe Ser Lys Thr Gln Trp Glu Phe Thr His
                 170                 175                 180

 His Thr Cys Ser Leu His Phe Pro His Glu Ser Leu Arg Glu Trp
                 185                 190                 195

 Lys Leu Phe Gln Ala Leu Lys Leu Asn Leu Phe Gly Leu Val Leu
                 200                 205                 210

 Pro Leu Leu Val Met Ile Ile Cys Tyr Thr Gly Ile Ile Lys Ile
                 215                 220                 225

 Leu Leu Arg Arg Pro Asn Glu Lys Lys Ser Lys Ala Val Arg Leu
                 230                 235                 240

 Ile Phe Val Ile Met Ile Ile Phe Phe Leu Phe Trp Thr Pro Tyr
                 245                 250                 255

 Asn Leu Thr Ile Leu Ile Ser Val Phe Gln Asp Phe Leu Phe Thr
                 260                 265                 270

 His Glu Cys Glu Gln Ser Arg His Leu Asp Leu Ala Val Gln Val
                 275                 280                 285

 Thr Glu Val Ile Ala Tyr Thr His Cys Cys Val Asn Pro Val Ile
                 290                 295                 300

 Tyr Ala Phe Val Gly Glu Arg Phe Arg Lys Tyr Leu Arg Gln Leu
                 305                 310                 315

 Phe His Arg Arg Val Ala Val His Leu Val Lys Trp Leu Pro Phe
                 320                 325                 330

 Leu Ser Val Asp Arg Leu Glu Arg Val Ser Ser Thr Ser Pro Ser
                 335                 340                 345

 Thr Gly Glu His Glu Leu Ser Ala Gly Phe
                 350                 355

<210> 5369
<211> 1292
<212> DNA
<213> Homo sapien

<400> 5369
 tgcgcggctt cctgcctcca tgccactcca gactgcaccg gcatggcact 50

 gactgcccac ccctcctgcc tcctggccct gttggtggca ggcctagccc 100

 aaggcatcag aggccccctt agggcccagg acctaggtcc ccagccgcta 150

 gagctgaaag aggccttcaa gttgttccag atccagttca accggagtta 200

 cctgagccca gaagagcatg ctcaccgcct ggacatcttt gcccacaacc 250

 tggcccaggc tcagaggctg caggaggagg acttgggcac agctgagttt 300

 ggggtgactc cattcagtga cctcacagag gaggagtttg gccagctcta 350

 tggctatcgg agggcagctg gaggggtccc cagcatgggc agagaaataa 400

 ggtctgaaga gccagaggag tcagtacctt tcagctgtga ctggcggaag 450

 gtggccggcg ccatctcacc catcaaggac cagaaaaact gcaactgctg 500

 ctgggccatg gcagcggcag gcaacataga gaccctgtgg cgcatcagtt 550

 tctgggattt tgtggacgtc tccgtgcagg aactgctgga ctgtggccgc 600

 tgtggggatg gctgccacgg tggcttcgtc tgggacgcgt tcataactgt 650

 cctcaacaac agcggcctgg ccagtgaaaa ggactacccg ttccagggca 700

 aagtcagagc ccacaggtgc caccccaaga agtaccagaa ggtggcctgg 750

 atccaggact tcatcatgct gcagaacaac gagcacagaa ttgcgcagta 800

 cctggccact tatggcccca tcaccgtgac catcaacatg aagccccttc 850

 agctataccg gaaaggtgtg atcaaggcca cacccaccac ctgtgacccc 900

 cagcttgtgg accactctgt cctgctggtg ggttttggca gcgtcaagtc 950

 agaggagggg atatgggcag agacagtctc atcgcagtct cagcctcagc 1000

 ctccacaccc caccccatac tggatcctga agaactcctg gggggcccaa 1050

 tggggagaga agggctattt ccggctgcac cgagggagca atacctgtgg 1100

 catcaccaag ttcccgctca ctgcccgtgt gcagaaaccg gatatgaagc 1150

 cccgagtctc ctgccctccc tgaccacctg gccccctcag ctctgtcctg 1200

 ttaggccaac tgcctccttg ccagccccac ccccaggttt ttgcccatcc 1250

 tcccaatctc aatacagcct gaataaacca agacaagacc tc 1292

<210> 5370
<211> 376
<212> PRT
<213> Homo sapien

<400> 5370
 Met Ala Leu Thr Ala His Pro Ser Cys Leu Leu Ala Leu Leu Val
   1               5                  10                  15

 Ala Gly Leu Ala Gln Gly Ile Arg Gly Pro Leu Arg Ala Gln Asp
                  20                  25                  30

 Leu Gly Pro Gln Pro Leu Glu Leu Lys Glu Ala Phe Lys Leu Phe
                  35                  40                  45

 Gln Ile Gln Phe Asn Arg Ser Tyr Leu Ser Pro Glu Glu His Ala
                  50                  55                  60

 His Arg Leu Asp Ile Phe Ala His Asn Leu Ala Gln Ala Gln Arg
                  65                  70                  75

 Leu Gln Glu Glu Asp Leu Gly Thr Ala Glu Phe Gly Val Thr Pro
                  80                  85                  90

 Phe Ser Asp Leu Thr Glu Glu Glu Phe Gly Gln Leu Tyr Gly Tyr
                  95                 100                 105

 Arg Arg Ala Ala Gly Gly Val Pro Ser Met Gly Arg Glu Ile Arg
                 110                 115                 120

 Ser Glu Glu Pro Glu Glu Ser Val Pro Phe Ser Cys Asp Trp Arg
                 125                 130                 135

 Lys Val Ala Gly Ala Ile Ser Pro Ile Lys Asp Gln Lys Asn Cys
                 140                 145                 150

 Asn Cys Cys Trp Ala Met Ala Ala Ala Gly Asn Ile Glu Thr Leu
                 155                 160                 165

 Trp Arg Ile Ser Phe Trp Asp Phe Val Asp Val Ser Val Gln Glu
                 170                 175                 180

 Leu Leu Asp Cys Gly Arg Cys Gly Asp Gly Cys His Gly Gly Phe
                 185                 190                 195

 Val Trp Asp Ala Phe Ile Thr Val Leu Asn Asn Ser Gly Leu Ala
                 200                 205                 210

 Ser Glu Lys Asp Tyr Pro Phe Gln Gly Lys Val Arg Ala His Arg
                 215                 220                 225

 Cys His Pro Lys Lys Tyr Gln Lys Val Ala Trp Ile Gln Asp Phe
                 230                 235                 240

 Ile Met Leu Gln Asn Asn Glu His Arg Ile Ala Gln Tyr Leu Ala
                 245                 250                 255

 Thr Tyr Gly Pro Ile Thr Val Thr Ile Asn Met Lys Pro Leu Gln
                 260                 265                 270

 Leu Tyr Arg Lys Gly Val Ile Lys Ala Thr Pro Thr Thr Cys Asp
                 275                 280                 285

 Pro Gln Leu Val Asp His Ser Val Leu Leu Val Gly Phe Gly Ser
                 290                 295                 300

 Val Lys Ser Glu Glu Gly Ile Trp Ala Glu Thr Val Ser Ser Gln
                 305                 310                 315

 Ser Gln Pro Gln Pro Pro His Pro Thr Pro Tyr Trp Ile Leu Lys
                 320                 325                 330

 Asn Ser Trp Gly Ala Gln Trp Gly Glu Lys Gly Tyr Phe Arg Leu
                 335                 340                 345

 His Arg Gly Ser Asn Thr Cys Gly Ile Thr Lys Phe Pro Leu Thr
                 350                 355                 360

 Ala Arg Val Gln Lys Pro Asp Met Lys Pro Arg Val Ser Cys Pro
                 365                 370                 375

 Pro


<210> 5371
<211> 2753
<212> DNA
<213> Homo sapien

<400> 5371
 gtcgggggca gcagcaagat gcgaagcgag ccgtacagat cccgggctct 50

 ccgaacgcaa cttcgccctg cttgagcgag gctgcggttt ccgaggccct 100

 ctccagccaa ggaaaagcta cacaaaaagc ctggatcact catcgaacca 150

 cccctgaagc cagtgaaggc tctctcgcct cgccctctag cgttcgtctg 200

 gagtagcgcc accccggctt cctggggaca cagggttggc accatggggc 250

 ccaccagcgt cccgctggtc aaggcccacc gcagctcggt ctctgactac 300

 gtcaactatg atatcatcgt ccggcattac aactacacgg gaaagctgaa 350

 tatcagcgcg gacaaggaga acagcattaa actgacctcg gtggtgttca 400

 ttctcatctg ctgctttatc atcctggaga acatctttgt cttgctgacc 450

 atttggaaaa ccaagaaatt ccaccgaccc atgtactatt ttattggcaa 500

 tctggccctc tcagacctgt tggcaggagt agcctacaca gctaacctgc 550

 tcttgtctgg ggccaccacc tacaagctca ctcccgccca gtggtttctg 600

 cgggaaggga gtatgtttgt ggccctgtca gcctccgtgt tcagtctcct 650

 cgccatcgcc attgagcgct atatcacaat gctgaaaatg aaactccaca 700

 acgggagcaa taacttccgc ctcttcctgc taatcagcgc ctgctgggtc 750

 atctccctca tcctgggtgg cctgcctatc atgggctgga actgcatcag 800

 tgcgctgtcc agctgctcca ccgtgctgcc gctctaccac aagcactata 850

 tcctcttctg caccacggtc ttcactctgc ttctgctctc catcgtcatt 900

 ctgtactgca gaatctactc cttggtcagg actcggagcc gccgcctgac 950

 gttccgcaag aacatttcca aggccagccg cagctctgag aagtcgctgg 1000

 cgctgctcaa gaccgtaatt atcgtcctga gcgtcttcat cgcctgctgg 1050

 gcaccgctct tcatcctgct cctgctggat gtgggctgca aggtgaagac 1100

 ctgtgacatc ctcttcagag cggagtactt cctggtgtta gctgtgctca 1150

 actccggcac caaccccatc atttacactc tgaccaacaa ggagatgcgt 1200

 cgggccttca tccggatcat gtcctgctgc aagtgcccga gcggagactc 1250

 tgctggcaaa ttcaagcgac ccatcatcgc cggcatggaa ttcagccgca 1300

 gcaaatcgga caattcctcc cacccccaga aagacgaagg ggacaaccca 1350

 gagaccatta tgtcttctgg aaacgtcaac tcttcttcct agaactggaa 1400

 gctgtccacc caccggaagc gctctttact tggtcgctgg ccaccccagt 1450

 gtttggaaaa aaatctctgg gcttcgactg ctgccaggga ggagctgctg 1500

 caagccagag ggaggaaggg ggagaatacg aacagcctgg tggtgtcggg 1550

 tgttggtggg tagagttagt tcctgtgaac aatgcactgg gaagggtgga 1600

 gatcaggtcc cggcctggaa tatatattct acccccctgg agctttgatt 1650

 ttgcactgag ccaaaggtct agcattgtca agctcctaaa gggttcattt 1700

 ggcccctcct caaagactaa tgtccccatg tgaaagcgtc tctttgtctg 1750

 gagctttgag gagatgtttt ccttcacttt agtttcaaac ccaagtgagt 1800

 gtgtgcactt ctgcttcttt agggatgccc tgtacatccc acaccccacc 1850

 ctcccttccc ttcatacccc tcctcaacgt tcttttactt tatactttaa 1900

 ctacctgaga gttatcagag ctggggttgt ggaatgatcg atcatctata 1950

 gcaaataggc tatgttgagt acgtaggctg tgggaagatg aagatggttt 2000

 ggaggtgtaa aacaatgtcc ttcgctgagg ccaaagtttc catgtaagcg 2050

 ggatccgttt tttggaattt ggttgaagtc actttgattt ctttaaaaaa 2100

 catcttttca atgaaatgtg ttaccatttc atatccattg aagccgaaat 2150

 ctgcataagg aagcccactt tatctaaatg atattagcca ggatccttgg 2200

 tgtcctagga gaaacagaca agcaaaacaa agtgaaaacc gaatggatta 2250

 acttttgcaa accaagggag atttcttagc aaatgagtct aacaaatatg 2300

 acatccgtct ttcccacttt tgttgatgtt tatttcagaa tcttgtgtga 2350

 ttcatttcaa gcaacaacat gttgtatttt gttgtgttaa aagtactttt 2400

 cttgattttt gaatgtattt gtttcaggaa gaagtcattt tatggatttt 2450

 tctaacccgt gttaactttt ctagaatcca ccctcttgtg cccttaagca 2500

 ttactttaac tggtagggaa cgccagaact tttaagtcca gctattcatt 2550

 agatagtaat tgaagatatg tataaatatt acaaagaata aaaatatatt 2600

 actgtctctt tagtatggtt ttcagtgcaa ttaaaccgag agatgtcttg 2650

 tttttttaaa aagaatagta tttaataggt ttctgacttt tgtggatcat 2700

 tttgcacata gctttatcaa cttttaaaca ttaataaact gattttttta 2750

 aag 2753

<210> 5372
<211> 382
<212> PRT
<213> Homo sapien

<400> 5372
 Met Gly Pro Thr Ser Val Pro Leu Val Lys Ala His Arg Ser Ser
   1               5                  10                  15

 Val Ser Asp Tyr Val Asn Tyr Asp Ile Ile Val Arg His Tyr Asn
                  20                  25                  30

 Tyr Thr Gly Lys Leu Asn Ile Ser Ala Asp Lys Glu Asn Ser Ile
                  35                  40                  45

 Lys Leu Thr Ser Val Val Phe Ile Leu Ile Cys Cys Phe Ile Ile
                  50                  55                  60

 Leu Glu Asn Ile Phe Val Leu Leu Thr Ile Trp Lys Thr Lys Lys
                  65                  70                  75

 Phe His Arg Pro Met Tyr Tyr Phe Ile Gly Asn Leu Ala Leu Ser
                  80                  85                  90

 Asp Leu Leu Ala Gly Val Ala Tyr Thr Ala Asn Leu Leu Leu Ser
                  95                 100                 105

 Gly Ala Thr Thr Tyr Lys Leu Thr Pro Ala Gln Trp Phe Leu Arg
                 110                 115                 120

 Glu Gly Ser Met Phe Val Ala Leu Ser Ala Ser Val Phe Ser Leu
                 125                 130                 135

 Leu Ala Ile Ala Ile Glu Arg Tyr Ile Thr Met Leu Lys Met Lys
                 140                 145                 150

 Leu His Asn Gly Ser Asn Asn Phe Arg Leu Phe Leu Leu Ile Ser
                 155                 160                 165

 Ala Cys Trp Val Ile Ser Leu Ile Leu Gly Gly Leu Pro Ile Met
                 170                 175                 180

 Gly Trp Asn Cys Ile Ser Ala Leu Ser Ser Cys Ser Thr Val Leu
                 185                 190                 195

 Pro Leu Tyr His Lys His Tyr Ile Leu Phe Cys Thr Thr Val Phe
                 200                 205                 210

 Thr Leu Leu Leu Leu Ser Ile Val Ile Leu Tyr Cys Arg Ile Tyr
                 215                 220                 225

 Ser Leu Val Arg Thr Arg Ser Arg Arg Leu Thr Phe Arg Lys Asn
                 230                 235                 240

 Ile Ser Lys Ala Ser Arg Ser Ser Glu Lys Ser Leu Ala Leu Leu
                 245                 250                 255

 Lys Thr Val Ile Ile Val Leu Ser Val Phe Ile Ala Cys Trp Ala
                 260                 265                 270

 Pro Leu Phe Ile Leu Leu Leu Leu Asp Val Gly Cys Lys Val Lys
                 275                 280                 285

 Thr Cys Asp Ile Leu Phe Arg Ala Glu Tyr Phe Leu Val Leu Ala
                 290                 295                 300

 Val Leu Asn Ser Gly Thr Asn Pro Ile Ile Tyr Thr Leu Thr Asn
                 305                 310                 315

 Lys Glu Met Arg Arg Ala Phe Ile Arg Ile Met Ser Cys Cys Lys
                 320                 325                 330

 Cys Pro Ser Gly Asp Ser Ala Gly Lys Phe Lys Arg Pro Ile Ile
                 335                 340                 345

 Ala Gly Met Glu Phe Ser Arg Ser Lys Ser Asp Asn Ser Ser His
                 350                 355                 360

 Pro Gln Lys Asp Glu Gly Asp Asn Pro Glu Thr Ile Met Ser Ser
                 365                 370                 375

 Gly Asn Val Asn Ser Ser Ser
                 380

<210> 5373
<211> 1202
<212> DNA
<213> Homo sapien

<400> 5373
 ggcacgaggc gccatttgct gccgccgagc gtggacgcag gcggatctct 50

 gaagagctgg gtcgccagcc tctcccgcgc acgttgcctg gcctccagca 100

 cctacttggt cccgcgcgct ccctcgtgtc gcccctcgga gcagcagccg 150

 ccgcggtcgc cgctacccgg aaagaagtca gagacgccgc gagtcgccgc 200

 caccgccatg cccaagaata aaggtaaagg aggtaaaaac agacgcaggg 250

 gtaagaatga gaatgaatct gaaaaaagag aactggtatt caaagaggat 300

 gggcaggagt atgctcaggt aatcaaaatg ttgggaaatg gacggctaga 350

 agcaatgtgt ttcgatggtg taaagaggtt atgtcacatc agaggaaaat 400

 tgagaaaaaa ggtttggata aatacctcgg acattatttt ggttggtctc 450

 cgagactacc aggataacaa agctgatgta attttaaaat acaatgcaga 500

 cgaagctaga agtctgaagg catacggcga gcttccagag catgctaaaa 550

 tcaatgaaac tgatacattt ggtcctggag atgatgatga aattcagttt 600

 gatgacattg gagatgatga tgaagatatt gatgacatct aaattgaact 650

 caacatttta cattccatct tttctgaaga ttgtcctaca atttggattt 700

 tgatcatgac aaagaagatt aaaatttcat tagcatgaat gcaatttgtt 750

 aaagcagact gatttgtttc taagatattt ttggtttttt taaaactgat 800

 aataatgctg aattatctta agtgagatgt taagcccact ttgttctttt 850

 aatgtaatgg agcttatggg tagaagacca tgtctactaa ttacaaaaaa 900

 aaaaaaaaac catgattgct gcttttccta ccacttccag taagaaaatg 950

 ggtgttttga agaaatcatt tgccttgtct cacggaatct gattaagccc 1000

 tggcctcttg atgtatagag tcatggatat tccagttacc tagatattcc 1050

 cttgagattt tgatacaatt tgagggaggc agaagtctgc agttgaagaa 1100

 aaaaaataag tctgtttgtc atatttaagt agcctgtgcg tatttttata 1150

 ctgattttga tatcatgttc ttttcatagt cgtattttgc caccgtaaac 1200

 at 1202

<210> 5374
<211> 144
<212> PRT
<213> Homo sapien

<400> 5374
 Met Pro Lys Asn Lys Gly Lys Gly Gly Lys Asn Arg Arg Arg Gly
   1               5                  10                  15

 Lys Asn Glu Asn Glu Ser Glu Lys Arg Glu Leu Val Phe Lys Glu
                  20                  25                  30

 Asp Gly Gln Glu Tyr Ala Gln Val Ile Lys Met Leu Gly Asn Gly
                  35                  40                  45

 Arg Leu Glu Ala Met Cys Phe Asp Gly Val Lys Arg Leu Cys His
                  50                  55                  60

 Ile Arg Gly Lys Leu Arg Lys Lys Val Trp Ile Asn Thr Ser Asp
                  65                  70                  75

 Ile Ile Leu Val Gly Leu Arg Asp Tyr Gln Asp Asn Lys Ala Asp
                  80                  85                  90

 Val Ile Leu Lys Tyr Asn Ala Asp Glu Ala Arg Ser Leu Lys Ala
                  95                 100                 105

 Tyr Gly Glu Leu Pro Glu His Ala Lys Ile Asn Glu Thr Asp Thr
                 110                 115                 120

 Phe Gly Pro Gly Asp Asp Asp Glu Ile Gln Phe Asp Asp Ile Gly
                 125                 130                 135

 Asp Asp Asp Glu Asp Ile Asp Asp Ile
                 140

<210> 5375
<211> 1383
<212> DNA
<213> Homo sapien

<400> 5375
 ctagtttcta aggatcatgt ctgcgagcca ggattcccga tccagagaca 50

 atggccccga tgggatggag cccgaaggcg tcatcgagag taactggaat 100

 gagattgttg acagctttga tgacatgaac ctctcggagt cccttctccg 150

 tggcatctac gcctatggtt ttgagaagcc ctctgccatc cagcagcgag 200

 ccattctacc ttgtatcaag ggttatgatg tgattgctca agcccaatct 250

 gggactggga aaacggccac atttgccata tcgattctgc agcagattga 300

 attagatcta aaagccaccc aggccttggt cctagcaccc actcgagaat 350

 tggctcagca gatacagaag gtggtcatgg cactaggaga ctacatgggc 400

 gcctcctgtc acgcctgtat cgggggcacc aacgtgcgtg ctgaggtgca 450

 gaaactgcag atggaagctc cccacatcat cgtgggtacc cctggccgtg 500

 tgtttgatat gcttaaccgg agatacctgt cccccaaata catcaagatg 550

 tttgtactgg atgaagctga cgaaatgtta agccgtggat tcaaggacca 600

 gatctatgac atattccaaa agctcaacag caacacccag gtagttttgc 650

 tgtcagccac aatgccttct gatgtgcttg aggtgaccaa gaagttcatg 700

 agggacccca ttcggattct tgtcaagaag gaagagttga ccctggaggg 750

 tatccgccag ttctacatca acgtggaacg agaggagtgg aagctggaca 800

 cactatgtga cttgtatgaa accctgacca tcacccaggc agtcatcttc 850

 atcaacaccc ggaggaaggt ggactggctc accgagaaga tgcatgctcg 900

 agatttcact gtatccgcca tgcatggaga tatggaccaa aaggaacgag 950

 acgtgattat gagggagttt cgttctggct ctagcagagt tttgattacc 1000

 actgacctgc tggccagagg cattgatgtg cagcaggttt ctttagtcat 1050

 caactatgac cttcccacca acagggaaaa ctatatccac agaatcggtc 1100

 gaggtggacg gtttggccgt aaaggtgtgg ctattaacat ggtgacagaa 1150

 gaagacaaga ggactcttcg agacattgag accttctaca acacctccat 1200

 tgaggaaatg cccctcaatg ttgctgacct catctgaggg gctgtcctgc 1250

 cacccagccc cagccagggc tcaatctctg ggggctgagg agcagcagga 1300

 ggggggaggg aagggagcca agggatggac atcttgtcat tttttttctt 1350

 tgaataaatg tcactttttg aggcaaaaga agg 1383

<210> 5376
<211> 406
<212> PRT
<213> Homo sapien

<400> 5376
 Met Ser Ala Ser Gln Asp Ser Arg Ser Arg Asp Asn Gly Pro Asp
   1               5                  10                  15

 Gly Met Glu Pro Glu Gly Val Ile Glu Ser Asn Trp Asn Glu Ile
                  20                  25                  30

 Val Asp Ser Phe Asp Asp Met Asn Leu Ser Glu Ser Leu Leu Arg
                  35                  40                  45

 Gly Ile Tyr Ala Tyr Gly Phe Glu Lys Pro Ser Ala Ile Gln Gln
                  50                  55                  60

 Arg Ala Ile Leu Pro Cys Ile Lys Gly Tyr Asp Val Ile Ala Gln
                  65                  70                  75

 Ala Gln Ser Gly Thr Gly Lys Thr Ala Thr Phe Ala Ile Ser Ile
                  80                  85                  90

 Leu Gln Gln Ile Glu Leu Asp Leu Lys Ala Thr Gln Ala Leu Val
                  95                 100                 105

 Leu Ala Pro Thr Arg Glu Leu Ala Gln Gln Ile Gln Lys Val Val
                 110                 115                 120

 Met Ala Leu Gly Asp Tyr Met Gly Ala Ser Cys His Ala Cys Ile
                 125                 130                 135

 Gly Gly Thr Asn Val Arg Ala Glu Val Gln Lys Leu Gln Met Glu
                 140                 145                 150

 Ala Pro His Ile Ile Val Gly Thr Pro Gly Arg Val Phe Asp Met
                 155                 160                 165

 Leu Asn Arg Arg Tyr Leu Ser Pro Lys Tyr Ile Lys Met Phe Val
                 170                 175                 180

 Leu Asp Glu Ala Asp Glu Met Leu Ser Arg Gly Phe Lys Asp Gln
                 185                 190                 195

 Ile Tyr Asp Ile Phe Gln Lys Leu Asn Ser Asn Thr Gln Val Val
                 200                 205                 210

 Leu Leu Ser Ala Thr Met Pro Ser Asp Val Leu Glu Val Thr Lys
                 215                 220                 225

 Lys Phe Met Arg Asp Pro Ile Arg Ile Leu Val Lys Lys Glu Glu
                 230                 235                 240

 Leu Thr Leu Glu Gly Ile Arg Gln Phe Tyr Ile Asn Val Glu Arg
                 245                 250                 255

 Glu Glu Trp Lys Leu Asp Thr Leu Cys Asp Leu Tyr Glu Thr Leu
                 260                 265                 270

 Thr Ile Thr Gln Ala Val Ile Phe Ile Asn Thr Arg Arg Lys Val
                 275                 280                 285

 Asp Trp Leu Thr Glu Lys Met His Ala Arg Asp Phe Thr Val Ser
                 290                 295                 300

 Ala Met His Gly Asp Met Asp Gln Lys Glu Arg Asp Val Ile Met
                 305                 310                 315

 Arg Glu Phe Arg Ser Gly Ser Ser Arg Val Leu Ile Thr Thr Asp
                 320                 325                 330

 Leu Leu Ala Arg Gly Ile Asp Val Gln Gln Val Ser Leu Val Ile
                 335                 340                 345

 Asn Tyr Asp Leu Pro Thr Asn Arg Glu Asn Tyr Ile His Arg Ile
                 350                 355                 360

 Gly Arg Gly Gly Arg Phe Gly Arg Lys Gly Val Ala Ile Asn Met
                 365                 370                 375

 Val Thr Glu Glu Asp Lys Arg Thr Leu Arg Asp Ile Glu Thr Phe
                 380                 385                 390

 Tyr Asn Thr Ser Ile Glu Glu Met Pro Leu Asn Val Ala Asp Leu
                 395                 400                 405

 Ile


<210> 5377
<211> 859
<212> DNA
<213> Homo sapien

<400> 5377
 tggaaagggc tgtcacccgg cttggcccct tccacaccca actggggcaa 50

 gcctgacccg gcgacaggag gcatgagggg cccccggccg aaatgacagt 100

 gctggcgcca gcctggagcc caacaaccta tctcctcctg ctgctgctgc 150

 tgagctcggg actcagtggg acccaggact gctccttcca acacagcccc 200

 atctcctccg acttcgctgt caaaatccgt gagctgtctg actacctgct 250

 tcaagattac ccagtcaccg tggcctccaa cctgcaggac gaggagctct 300

 gcggggcgct ctggcggctg gtcctggcac agcgctggat ggagcggctc 350

 aagactgtcg ctgggtccaa gatgcaaggc ttgctggagc gcgtgaacac 400

 ggagatacac tttgtcacca aatgtgcctt tcagcccccc cccagctgtc 450

 ttcgcttcgt ccagaccaac atctcccgcc tcctgcagga gacctccgag 500

 cagctggtgg cgctgaagcc ctggatcact cgccagaact tctcccggtg 550

 cctggagctg cagtgtcagc ccgactcctc aaccctgcca cccccatgga 600

 gtccccggcc cctggaggcc acagccccga cagccccgca gccccctctg 650

 ctcctcctac tgctgctgcc cgtgggcctc ctgctgctgg ccgctgcctg 700

 gtgcctgcac tggcagagga cgcggcggag gacaccccgc cctggggagc 750

 aggtgccccc cgtccccagt ccccaggacc tgctgcttgt ggagcactga 800

 cctggccaag gcctcatcct ggggaggata cgtaggcaca cagaggggag 850

 tcaccagcc 859

<210> 5378
<211> 235
<212> PRT
<213> Homo sapien

<400> 5378
 Met Thr Val Leu Ala Pro Ala Trp Ser Pro Thr Thr Tyr Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Leu Ser Ser Gly Leu Ser Gly Thr Gln Asp Cys
                  20                  25                  30

 Ser Phe Gln His Ser Pro Ile Ser Ser Asp Phe Ala Val Lys Ile
                  35                  40                  45

 Arg Glu Leu Ser Asp Tyr Leu Leu Gln Asp Tyr Pro Val Thr Val
                  50                  55                  60

 Ala Ser Asn Leu Gln Asp Glu Glu Leu Cys Gly Ala Leu Trp Arg
                  65                  70                  75

 Leu Val Leu Ala Gln Arg Trp Met Glu Arg Leu Lys Thr Val Ala
                  80                  85                  90

 Gly Ser Lys Met Gln Gly Leu Leu Glu Arg Val Asn Thr Glu Ile
                  95                 100                 105

 His Phe Val Thr Lys Cys Ala Phe Gln Pro Pro Pro Ser Cys Leu
                 110                 115                 120

 Arg Phe Val Gln Thr Asn Ile Ser Arg Leu Leu Gln Glu Thr Ser
                 125                 130                 135

 Glu Gln Leu Val Ala Leu Lys Pro Trp Ile Thr Arg Gln Asn Phe
                 140                 145                 150

 Ser Arg Cys Leu Glu Leu Gln Cys Gln Pro Asp Ser Ser Thr Leu
                 155                 160                 165

 Pro Pro Pro Trp Ser Pro Arg Pro Leu Glu Ala Thr Ala Pro Thr
                 170                 175                 180

 Ala Pro Gln Pro Pro Leu Leu Leu Leu Leu Leu Leu Pro Val Gly
                 185                 190                 195

 Leu Leu Leu Leu Ala Ala Ala Trp Cys Leu His Trp Gln Arg Thr
                 200                 205                 210

 Arg Arg Arg Thr Pro Arg Pro Gly Glu Gln Val Pro Pro Val Pro
                 215                 220                 225

 Ser Pro Gln Asp Leu Leu Leu Val Glu His
                 230                 235

<210> 5379
<211> 1670
<212> DNA
<213> Homo sapien

<400> 5379
 ccaaccacaa gcaccaaagc agaggggcag gcagcacacc acccagcagc 50

 cagagcacca gcccagccat ggtccttgag gtgagtgacc accaagtgct 100

 aaatgacgcc gaggttgccg ccctcctgga gaacttcagc tcttcctatg 150

 actatggaga aaacgagagt gactcgtgct gtacctcccc gccctgccca 200

 caggacttca gcctgaactt cgaccgggcc ttcctgccag ccctctacag 250

 cctcctcttt ctgctggggc tgctgggcaa cggcgcggtg gcagccgtgc 300

 tgctgagccg gcggacagcc ctgagcagca ccgacacctt cctgctccac 350

 ctagctgtag cagacacgct gctggtgctg acactgccgc tctgggcagt 400

 ggacgctgcc gtccagtggg tctttggctc tggcctctgc aaagtggcag 450

 gtgccctctt caacatcaac ttctacgcag gagccctcct gctggcctgc 500

 atcagctttg accgctacct gaacatagtt catgccaccc agctctaccg 550

 ccgggggccc ccggcccgcg tgaccctcac ctgcctggct gtctgggggc 600

 tctgcctgct tttcgccctc ccagacttca tcttcctgtc ggcccaccac 650

 gacgagcgcc tcaacgccac ccactgccaa tacaacttcc cacaggtggg 700

 ccgcacggct ctgcgggtgc tgcagctggt ggctggcttt ctgctgcccc 750

 tgctggtcat ggcctactgc tatgcccaca tcctggccgt gctgctggtt 800

 tccaggggcc agcggcgcct gcgggccatg cggctggtgg tggtggtcgt 850

 ggtggccttt gccctctgct ggacccccta tcacctggtg gtgctggtgg 900

 acatcctcat ggacctgggc gctttggccc gcaactgtgg ccgagaaagc 950

 agggtagacg tggccaagtc ggtcacctca ggcctgggct acatgcactg 1000

 ctgcctcaac ccgctgctct atgcctttgt aggggtcaag ttccgggagc 1050

 ggatgtggat gctgctcttg cgcctgggct gccccaacca gagagggctc 1100

 cagaggcagc catcgtcttc ccgccgggat tcatcctggt ctgagacctc 1150

 agaggcctcc tactcgggct tgtgaggccg gaatccgggc tcccctttcg 1200

 cccacagtct gacttccccg cattccaggc tcctccctcc ctctgccggc 1250

 tctggctctc cccaatatcc tcgctcccgg gactcactgg cagccccagc 1300

 accaccaggt ctcccgggaa gccaccctcc cagctctgag gactgcacca 1350

 ttgctgctcc ttagctgcca agccccatcc tgccgcccga ggtggctgcc 1400

 tggagcccca ctgcccttct catttggaaa ctaaaacttc atcttcccca 1450

 agtgcgggga gtacaaggca tggcgtagag ggtgctgccc catgaagcca 1500

 cagcccaggc ctccagctca gcagtgactg tggccatggt ccccaagacc 1550

 tctatatttg ctcttttatt tttatgtcta aaatcctgct taaaactttt 1600

 caataaacaa gatcgtcagg accaaaaaaa aaaaaaaaaa aaaaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaaa 1670

<210> 5380
<211> 368
<212> PRT
<213> Homo sapien

<400> 5380
 Met Val Leu Glu Val Ser Asp His Gln Val Leu Asn Asp Ala Glu
   1               5                  10                  15

 Val Ala Ala Leu Leu Glu Asn Phe Ser Ser Ser Tyr Asp Tyr Gly
                  20                  25                  30

 Glu Asn Glu Ser Asp Ser Cys Cys Thr Ser Pro Pro Cys Pro Gln
                  35                  40                  45

 Asp Phe Ser Leu Asn Phe Asp Arg Ala Phe Leu Pro Ala Leu Tyr
                  50                  55                  60

 Ser Leu Leu Phe Leu Leu Gly Leu Leu Gly Asn Gly Ala Val Ala
                  65                  70                  75

 Ala Val Leu Leu Ser Arg Arg Thr Ala Leu Ser Ser Thr Asp Thr
                  80                  85                  90

 Phe Leu Leu His Leu Ala Val Ala Asp Thr Leu Leu Val Leu Thr
                  95                 100                 105

 Leu Pro Leu Trp Ala Val Asp Ala Ala Val Gln Trp Val Phe Gly
                 110                 115                 120

 Ser Gly Leu Cys Lys Val Ala Gly Ala Leu Phe Asn Ile Asn Phe
                 125                 130                 135

 Tyr Ala Gly Ala Leu Leu Leu Ala Cys Ile Ser Phe Asp Arg Tyr
                 140                 145                 150

 Leu Asn Ile Val His Ala Thr Gln Leu Tyr Arg Arg Gly Pro Pro
                 155                 160                 165

 Ala Arg Val Thr Leu Thr Cys Leu Ala Val Trp Gly Leu Cys Leu
                 170                 175                 180

 Leu Phe Ala Leu Pro Asp Phe Ile Phe Leu Ser Ala His His Asp
                 185                 190                 195

 Glu Arg Leu Asn Ala Thr His Cys Gln Tyr Asn Phe Pro Gln Val
                 200                 205                 210

 Gly Arg Thr Ala Leu Arg Val Leu Gln Leu Val Ala Gly Phe Leu
                 215                 220                 225

 Leu Pro Leu Leu Val Met Ala Tyr Cys Tyr Ala His Ile Leu Ala
                 230                 235                 240

 Val Leu Leu Val Ser Arg Gly Gln Arg Arg Leu Arg Ala Met Arg
                 245                 250                 255

 Leu Val Val Val Val Val Val Ala Phe Ala Leu Cys Trp Thr Pro
                 260                 265                 270

 Tyr His Leu Val Val Leu Val Asp Ile Leu Met Asp Leu Gly Ala
                 275                 280                 285

 Leu Ala Arg Asn Cys Gly Arg Glu Ser Arg Val Asp Val Ala Lys
                 290                 295                 300

 Ser Val Thr Ser Gly Leu Gly Tyr Met His Cys Cys Leu Asn Pro
                 305                 310                 315

 Leu Leu Tyr Ala Phe Val Gly Val Lys Phe Arg Glu Arg Met Trp
                 320                 325                 330

 Met Leu Leu Leu Arg Leu Gly Cys Pro Asn Gln Arg Gly Leu Gln
                 335                 340                 345

 Arg Gln Pro Ser Ser Ser Arg Arg Asp Ser Ser Trp Ser Glu Thr
                 350                 355                 360

 Ser Glu Ala Ser Tyr Ser Gly Leu
                 365

<210> 5381
<211> 2160
<212> DNA
<213> Homo sapien

<400> 5381
 agccccctgc ccctcgccgc cccccgccgc ctgcctgggc cgggccgagg 50

 atgcggcgca gcgcctcggc ggccaggctt gctcccctcc ggcacgcctg 100

 ctaacttccc ccgctacgtc cccgttcgcc cgccgggccg ccccgtctcc 150

 ccgcggcctc cgggtccggg tcctccagga cggccaggcc gtgccgccgt 200

 gtgccctccg ccgctcgccc gcgcgccgcg cgctccccgc ctgcgcccag 250

 cgccccgcgc ccgcgcccca gtcctcgggc ggtccatgct gcccctctgc 300

 ctcgtggccg ccctgctgct ggccgccggg cccgggccga gcctgggcga 350

 cgaagccatc cactgcccgc cctgctccga ggagaagctg gcgcgctgcc 400

 gcccccccgt gggctgcgag gagctggtgc gagaggcggg ctgcggctgt 450

 tgcgccactt gcgccctggg cttggggatg ccctgcgggg tgtacacccc 500

 ccgttgcggc tcgggcctgc gctgctaccc gccccgaggg gtggagaagc 550

 ccctgcacac actgatgcac gggcaaggcg tgtgcatgga gctggcggag 600

 atcgaggcca tccaggaaag cctgcagccc tctgacaagg acgagggtga 650

 ccaccccaac aacagcttca gcccctgtag cgcccatgac cgcaggtgcc 700

 tgcagaagca cttcgccaaa attcgagacc ggagcaccag tgggggcaag 750

 atgaaggtca atggggcgcc ccgggaggat gcccggcctg tgccccaggg 800

 ctcctgccag agcgagctgc accgggcgct ggagcggctg gccgcttcac 850

 agagccgcac ccacgaggac ctctacttca tccccatccc caactgcgac 900

 cgcaacggca acttccaccc caagcagtgt cacccagctc tggatgggca 950

 gcgtggcaag tgctggtgtg tggaccggaa gacgggggtg aagcttccgg 1000

 ggggcctgga gccaaagggg gagctggact gccaccagct ggctgacagc 1050

 tttcgagagt gaggcctgcc agcaggccag ggactcagcg tcccctgcta 1100

 ctcctgtgct ctggaggctg cagagctgac ccagagtgga gtctgagtct 1150

 gagtcctgtc tctgcctgcg gcccagaagt ttccctcaaa tgcgcgtgtg 1200

 cacgtgtgcg tgtgcgtgcg tgtgtgtgtg tttgtgagca tgggtgtgcc 1250

 cttggggtaa gccagagcct ggggtgttct ctttggtgtt acacagccca 1300

 agaggactga gactggcact tagcccaaga ggtctgagcc ctggtgtgtt 1350

 tccagatcga tcctggattc actcactcac tcattccttc actcatccag 1400

 ccacctaaaa acatttactg accatgtact acgtgccagc tctagttttc 1450

 agccttggga ggttttattc tgacttcctc tgattttggc atgtggagac 1500

 actcctataa ggagagttca agcctgtggg agtagaaaaa tctcattccc 1550

 agagtcagag gagaagagac atgtaccttg accatcgtcc ttcctctcaa 1600

 gctagcccag agggtgggag cctaaggaag cgtggggtag cagatggagt 1650

 aatggtcacg aggtccagac ccactcccaa agctcagact tgccaggctc 1700

 cctttctctt cttccccagg tccttccttt aggtctggtt gttgcaccat 1750

 ctgcttggtt ggctggcagc tgagagccct gctgtgggag agcgaagggg 1800

 gtcaaaggaa gacttgaagc acagagggct agggaggtgg ggtacatttc 1850

 tctgagcagt cagggtggga agaaagaatg caagagtgga ctgaatgtgc 1900

 ctaatggaga agacccacgt gctaggggat gaggggcttc ctgggtcctg 1950

 ttcccctacc ccatttgtgg tcacagccat gaagtcaccg ggatgaacct 2000

 atccttccag tggctcgctc cctgtagctc tgcctccctc tccatatctc 2050

 cttcccctac acctccctcc ccacacctcc ctactcccct gggcatcttc 2100

 tggcttgact ggatggaagg agacttagga acctaccagt tggccatgat 2150

 gtcttttctt 2160

<210> 5382
<211> 258
<212> PRT
<213> Homo sapien

<400> 5382
 Met Leu Pro Leu Cys Leu Val Ala Ala Leu Leu Leu Ala Ala Gly
   1               5                  10                  15

 Pro Gly Pro Ser Leu Gly Asp Glu Ala Ile His Cys Pro Pro Cys
                  20                  25                  30

 Ser Glu Glu Lys Leu Ala Arg Cys Arg Pro Pro Val Gly Cys Glu
                  35                  40                  45

 Glu Leu Val Arg Glu Ala Gly Cys Gly Cys Cys Ala Thr Cys Ala
                  50                  55                  60

 Leu Gly Leu Gly Met Pro Cys Gly Val Tyr Thr Pro Arg Cys Gly
                  65                  70                  75

 Ser Gly Leu Arg Cys Tyr Pro Pro Arg Gly Val Glu Lys Pro Leu
                  80                  85                  90

 His Thr Leu Met His Gly Gln Gly Val Cys Met Glu Leu Ala Glu
                  95                 100                 105

 Ile Glu Ala Ile Gln Glu Ser Leu Gln Pro Ser Asp Lys Asp Glu
                 110                 115                 120

 Gly Asp His Pro Asn Asn Ser Phe Ser Pro Cys Ser Ala His Asp
                 125                 130                 135

 Arg Arg Cys Leu Gln Lys His Phe Ala Lys Ile Arg Asp Arg Ser
                 140                 145                 150

 Thr Ser Gly Gly Lys Met Lys Val Asn Gly Ala Pro Arg Glu Asp
                 155                 160                 165

 Ala Arg Pro Val Pro Gln Gly Ser Cys Gln Ser Glu Leu His Arg
                 170                 175                 180

 Ala Leu Glu Arg Leu Ala Ala Ser Gln Ser Arg Thr His Glu Asp
                 185                 190                 195

 Leu Tyr Phe Ile Pro Ile Pro Asn Cys Asp Arg Asn Gly Asn Phe
                 200                 205                 210

 His Pro Lys Gln Cys His Pro Ala Leu Asp Gly Gln Arg Gly Lys
                 215                 220                 225

 Cys Trp Cys Val Asp Arg Lys Thr Gly Val Lys Leu Pro Gly Gly
                 230                 235                 240

 Leu Glu Pro Lys Gly Glu Leu Asp Cys His Gln Leu Ala Asp Ser
                 245                 250                 255

 Phe Arg Glu


<210> 5383
<211> 3649
<212> DNA
<213> Homo sapien

<400> 5383
 agtcccagcc caagggtagc tggaggcgcg caggccggct ccgctccggc 50

 cccggacgat gcggcgcgcc caggatgctg ccgtgcctcg tagtgctgct 100

 ggcggcgctc ctcagcctcc gtcttggctc agacgctcat gggacagagc 150

 tgcccagccc tccgtctgtg tggtttgaag cagaattttt ccaccacatc 200

 ctccactgga cacccatccc aaatcagtct gaaagtacct gctatgaagt 250

 ggcgctcctg aggtatggaa tagagtcctg gaactccatc tccaactgta 300

 gccagaccct gtcctatgac cttaccgcag tgaccttgga cctgtaccac 350

 agcaatggct accgggccag agtgcgggct gtggacggca gccggcactc 400

 caactggacc gtcaccaaca cccgcttctc tgtggatgaa gtgactctga 450

 cagttggcag tgtgaaccta gagatccaca atggcttcat cctcgggaag 500

 attcagctac ccaggcccaa gatggccccc gcaaatgaca catatgaaag 550

 catcttcagt cacttccgag agtatgagat tgccattcgc aaggtgccgg 600

 gaaacttcac gttcacacac aagaaagtaa aacatgaaaa cttcagcctc 650

 ctaacctctg gagaagtggg agagttctgt gtccaggtga aaccatctgt 700

 cgcttcccga agtaacaagg ggatgtggtc taaagaggag tgcatctccc 750

 tcaccaggca gtatttcacc gtgaccaacg tcatcatctt ctttgccttt 800

 gtcctgctgc tctccggagc cctcgcctac tgcctggccc tccagctgta 850

 tgtgcggcgc cgaaagaagc tacccagtgt cctgctcttc aagaagccca 900

 gccccttcat cttcatcagc cagcgtccct ccccagagac ccaagacacc 950

 atccacccgc ttgatgagga ggcctttttg aaggtgtccc cagagctgaa 1000

 gaacttggac ctgcacggca gcacagacag tggctttggc agcaccaagc 1050

 catccctgca gactgaagag ccccagttcc tcctccctga ccctcacccc 1100

 caggctgaca gaacgctggg aaacggggag ccccctgtgc tgggggacag 1150

 ctgcagtagt ggcagcagca atagcacaga cagcgggatc tgcctgcagg 1200

 agcccagcct gagccccagc acagggccca cctgggagca acaggtgggg 1250

 agcaacagca ggggccagga tgacagtggc attgacttag ttcaaaactc 1300

 tgagggccgg gctggggaca cacagggtgg ctcggccttg ggccaccaca 1350

 gtcccccgga gcctgaggtg cctggggaag aagacccagc tgctgtggca 1400

 ttccagggtt acctgaggca gaccagatgt gctgaagaga aggcaaccaa 1450

 gacaggctgc ctggaggaag aatcgccctt gacagatggc cttggcccca 1500

 aattcgggag atgcctggtt gatgaggcag gcttgcatcc accagccctg 1550

 gccaagggct atttgaaaca ggatcctcta gaaatgactc tggcttcctc 1600

 aggggcccca acgggacagt ggaaccagcc cactgaggaa tggtcactcc 1650

 tggccttgag cagctgcagt gacctgggaa tatctgactg gagctttgcc 1700

 catgaccttg cccctctagg ctgtgtggca gccccaggtg gtctcctggg 1750

 cagctttaac tcagacctgg tcaccctgcc cctcatctct agcctgcagt 1800

 caagtgagtg actcgggctg agaggctgct tttgatttta gccatgcctg 1850

 ctcctctgcc tggaccagga ggagggcccc tggggcagaa gttaggcacg 1900

 aggcagtctg ggcacttttc tgcaagtcca ctggggctgg ccccagccag 1950

 gccctgcagg gctggtcagg gtgtctgggg caggaggagg ccaactcact 2000

 gaactagtgc agggtatgtg ggtggcactg acctgttctg ttgactgggg 2050

 ccctgcagac tctggcagag ctgagaaggg cagggacctt ctccctccta 2100

 ggaactcttt cctgtatcat aaaggattat ttgctcaggg gaaccatggg 2150

 gctttctgga gttgtggtga ggccaccagg ctgaagtcag ctcagaccca 2200

 gacctccctg cttaggccac tcgagcatca gagcttccag caggaggaag 2250

 ggctgtagga atggaagctt cagggccttg ctgctggggt catttttagg 2300

 ggaaaaagga ggatatgatg gtcacatggg gaacctcccc tcatcgggcc 2350

 tctggggcag gaagcttgtc actggaagat cttaaggtat atattttctg 2400

 gacactcaaa cacatcataa tggattcact gaggggagac aaagggagcc 2450

 gagaccctgg atggggcttc cagctcagaa cccatccctc tggtgggtac 2500

 ctctggcacc catctgcaaa tatctccctc tctccaacaa atggagtagc 2550

 atccccctgg ggcacttgct gaggccaagc cactcacatc ctcactttgc 2600

 tgccccacca tcttgctgac aacttccaga gaagccatgg ttttttgtat 2650

 tggtcataac tcagcccttt gggcggcctc tgggcttggg caccagctca 2700

 tgccagcccc agagggtcag ggttggaggc ctgtgcttgt gtttgctgct 2750

 aatgtccagc tacagaccca gaggataagc cactgggcac tgggctgggg 2800

 tccctgcctt gttggtgttc agctgtgtga ttttggacta gccacttgtc 2850

 agagggcctc aatctcccat ctgtgaaata aggactccac ctttagggga 2900

 ccctccatgt ttgctgggta ttagccaagc tggtcctggg agaatgcaga 2950

 tactgtccgt ggactaccaa gctggcttgt ttcttatgcc agaggctaac 3000

 agatccaatg ggagtccatg gtgtcatgcc aagacagtat cagacacagc 3050

 cccagaaggg ggcattatgg gccctgcctc cccataggcc atttggactc 3100

 tgccttcaaa caaaggcagt tcagtccaca ggcatggaag ctgtgagggg 3150

 acaggcctgt gcgtgccatc cagagtcatc tcagccctgc ctttctctgg 3200

 agcattctga aaacagatat tctggcccag ggaatccagc catgaccccc 3250

 acccctctgc caaagtactc ttaggtgcca gtctggtaac tgaactccct 3300

 ctggaggcag gcttgaggga ggattcctca gggttccctt gaaagcttta 3350

 tttatttatt ttgttcattt atttattgga gaggcagcat tgcacagtga 3400

 aagaattctg gatatctcag gagccccgaa attctagctc tgactttgct 3450

 gtttccagtg gtatgacctt ggagaagtca cttatcctct tggagcctca 3500

 gtttcctcat ctgcagaata atgactgact tgtctaattc gtagggatgt 3550

 gaggttctgc tgaggaaatg ggtatgaatg tgccttgaac acaaagctct 3600

 gtcaataagt gatacatgtt ttttattcca ataaattgtc aagaccaca 3649

<210> 5384
<211> 578
<212> PRT
<213> Homo sapien

<400> 5384
 Met Leu Pro Cys Leu Val Val Leu Leu Ala Ala Leu Leu Ser Leu
   1               5                  10                  15

 Arg Leu Gly Ser Asp Ala His Gly Thr Glu Leu Pro Ser Pro Pro
                  20                  25                  30

 Ser Val Trp Phe Glu Ala Glu Phe Phe His His Ile Leu His Trp
                  35                  40                  45

 Thr Pro Ile Pro Asn Gln Ser Glu Ser Thr Cys Tyr Glu Val Ala
                  50                  55                  60

 Leu Leu Arg Tyr Gly Ile Glu Ser Trp Asn Ser Ile Ser Asn Cys
                  65                  70                  75

 Ser Gln Thr Leu Ser Tyr Asp Leu Thr Ala Val Thr Leu Asp Leu
                  80                  85                  90

 Tyr His Ser Asn Gly Tyr Arg Ala Arg Val Arg Ala Val Asp Gly
                  95                 100                 105

 Ser Arg His Ser Asn Trp Thr Val Thr Asn Thr Arg Phe Ser Val
                 110                 115                 120

 Asp Glu Val Thr Leu Thr Val Gly Ser Val Asn Leu Glu Ile His
                 125                 130                 135

 Asn Gly Phe Ile Leu Gly Lys Ile Gln Leu Pro Arg Pro Lys Met
                 140                 145                 150

 Ala Pro Ala Asn Asp Thr Tyr Glu Ser Ile Phe Ser His Phe Arg
                 155                 160                 165

 Glu Tyr Glu Ile Ala Ile Arg Lys Val Pro Gly Asn Phe Thr Phe
                 170                 175                 180

 Thr His Lys Lys Val Lys His Glu Asn Phe Ser Leu Leu Thr Ser
                 185                 190                 195

 Gly Glu Val Gly Glu Phe Cys Val Gln Val Lys Pro Ser Val Ala
                 200                 205                 210

 Ser Arg Ser Asn Lys Gly Met Trp Ser Lys Glu Glu Cys Ile Ser
                 215                 220                 225

 Leu Thr Arg Gln Tyr Phe Thr Val Thr Asn Val Ile Ile Phe Phe
                 230                 235                 240

 Ala Phe Val Leu Leu Leu Ser Gly Ala Leu Ala Tyr Cys Leu Ala
                 245                 250                 255

 Leu Gln Leu Tyr Val Arg Arg Arg Lys Lys Leu Pro Ser Val Leu
                 260                 265                 270

 Leu Phe Lys Lys Pro Ser Pro Phe Ile Phe Ile Ser Gln Arg Pro
                 275                 280                 285

 Ser Pro Glu Thr Gln Asp Thr Ile His Pro Leu Asp Glu Glu Ala
                 290                 295                 300

 Phe Leu Lys Val Ser Pro Glu Leu Lys Asn Leu Asp Leu His Gly
                 305                 310                 315

 Ser Thr Asp Ser Gly Phe Gly Ser Thr Lys Pro Ser Leu Gln Thr
                 320                 325                 330

 Glu Glu Pro Gln Phe Leu Leu Pro Asp Pro His Pro Gln Ala Asp
                 335                 340                 345

 Arg Thr Leu Gly Asn Gly Glu Pro Pro Val Leu Gly Asp Ser Cys
                 350                 355                 360

 Ser Ser Gly Ser Ser Asn Ser Thr Asp Ser Gly Ile Cys Leu Gln
                 365                 370                 375

 Glu Pro Ser Leu Ser Pro Ser Thr Gly Pro Thr Trp Glu Gln Gln
                 380                 385                 390

 Val Gly Ser Asn Ser Arg Gly Gln Asp Asp Ser Gly Ile Asp Leu
                 395                 400                 405

 Val Gln Asn Ser Glu Gly Arg Ala Gly Asp Thr Gln Gly Gly Ser
                 410                 415                 420

 Ala Leu Gly His His Ser Pro Pro Glu Pro Glu Val Pro Gly Glu
                 425                 430                 435

 Glu Asp Pro Ala Ala Val Ala Phe Gln Gly Tyr Leu Arg Gln Thr
                 440                 445                 450

 Arg Cys Ala Glu Glu Lys Ala Thr Lys Thr Gly Cys Leu Glu Glu
                 455                 460                 465

 Glu Ser Pro Leu Thr Asp Gly Leu Gly Pro Lys Phe Gly Arg Cys
                 470                 475                 480

 Leu Val Asp Glu Ala Gly Leu His Pro Pro Ala Leu Ala Lys Gly
                 485                 490                 495

 Tyr Leu Lys Gln Asp Pro Leu Glu Met Thr Leu Ala Ser Ser Gly
                 500                 505                 510

 Ala Pro Thr Gly Gln Trp Asn Gln Pro Thr Glu Glu Trp Ser Leu
                 515                 520                 525

 Leu Ala Leu Ser Ser Cys Ser Asp Leu Gly Ile Ser Asp Trp Ser
                 530                 535                 540

 Phe Ala His Asp Leu Ala Pro Leu Gly Cys Val Ala Ala Pro Gly
                 545                 550                 555

 Gly Leu Leu Gly Ser Phe Asn Ser Asp Leu Val Thr Leu Pro Leu
                 560                 565                 570

 Ile Ser Ser Leu Gln Ser Ser Glu
                 575

<210> 5385
<211> 4040
<212> DNA
<213> Homo sapien

<400> 5385
 tgcagagcac agagaaagga catctgcgag gaaagttccc tgatggctgt 50

 caacaaagtg ccacgtctct atggctgtga acgctgagca cacgatttta 100

 tcgcgcctat catatcttgg tgcataaacg cacctcacct cggtcaaccc 150

 ttgctccgtc ttatgagaca ggctttatta tccgcatttt atatgagggg 200

 aaactgacgg tggagagaga attatcttgc tcaaggcgac acagcagagc 250

 ccacaggtgg cagaatccca cccgagcccg cttcgacccg cggggtggaa 300

 accacgggcg cccgcccggc tgcgcttcca gagctgaact gagaagcgag 350

 tcctctccgc cctgcggcca ccgcccagcc ccgacccccg ccccggcccg 400

 atcctcactc gccgccagct ccccgcgccc accccggagt tggtggcgca 450

 gaggcgggag gcggaggcgg gagggcgggc gctggcaccg ggaacgcccg 500

 agcgccggca gagagcgcgg agagcgcgac acgtgcggcc cagagcaccg 550

 gggccacccg gtccccgcag gcccgggacc gcgcccgctg gcaggcgaca 600

 cgtggaagaa tacggagttc tataccagag ttgattgttg atggcacata 650

 cttttagagg atgctcattg gcatttatgt ttataatcac gtggctgttg 700

 attaaagcaa aaatagatgc gtgcaagaga ggcgatgtga ctgtgaagcc 750

 ttcccatgta attttacttg gatccactgt caatattaca tgctctttga 800

 agcccagaca aggctgcttt cactattcca gacgtaacaa gttaatcctg 850

 tacaagtttg acagaagaat caattttcac catggccact ccctcaattc 900

 tcaagtcaca ggtcttcccc ttggtacaac cttgtttgtc tgcaaactgg 950

 cctgtatcaa tagtgatgaa attcaaatat gtggagcaga gatcttcgtt 1000

 ggtgttgctc cagaacagcc tcaaaattta tcctgcatac agaagggaga 1050

 acaggggact gtggcctgca cctgggaaag aggacgagac acccacttat 1100

 acactgagta tactctacag ctaagtggac caaaaaattt aacctggcag 1150

 aagcaatgta aagacattta ttgtgactat ttggactttg gaatcaacct 1200

 cacccctgaa tcacctgaat ccaatttcac agccaaggtt actgctgtca 1250

 atagtcttgg aagctcctct tcacttccat ccacattcac attcttggac 1300

 atagtgaggc ctcttcctcc gtgggacatt agaatcaaat ttcaaaaggc 1350

 ttctgtgagc agatgtaccc tttattggag agatgaggga ctggtactgc 1400

 ttaatcgact cagatatcgg cccagtaaca gcaggctctg gaatatggtt 1450

 aatgttacaa aggccaaagg aagacatgat ttgctggatc tgaaaccatt 1500

 tacagaatat gaatttcaga tttcctctaa gctacatctt tataagggaa 1550

 gttggagtga ttggagtgaa tcattgagag cacaaacacc agaagaagag 1600

 cctactggga tgttagatgt ctggtacatg aaacggcaca ttgactacag 1650

 tagacaacag atttctcttt tctggaagaa tctgagtgtc tcagaggcaa 1700

 gaggaaaaat tctccactat caggtgacct tgcaggagct gacaggaggg 1750

 aaagccatga cacagaacat cacaggacac acctcctgga ccacagtcat 1800

 tcctagaacc ggaaattggg ctgtggctgt gtctgcagca aattcaaaag 1850

 gcagttctct gcccactcgt attaacataa tgaacctgtg tgaggcaggg 1900

 ttgctggctc ctcgccaggt ctctgcaaac tcagagggca tggacaacat 1950

 tctggtgact tggcagcctc ccaggaaaga tccctctgct gttcaggagt 2000

 acgtggtgga atggagagag ctccatccag ggggtgacac acaggtccct 2050

 ctaaactggc tacggagtcg accctacaat gtgtctgctc tgatttcaga 2100

 gaacataaaa tcctacatct gttatgaaat ccgtgtgtat gcactctcag 2150

 gggatcaagg aggatgcagc tccatcctgg gtaactctaa gcacaaagca 2200

 ccactgagtg gcccccacat taatgccatc acagaggaaa aggggagcat 2250

 tttaatttca tggaacagca ttccagtcca ggagcaaatg ggctgcctcc 2300

 tccattatag gatatactgg aaggaacggg actccaactc ccagcctcag 2350

 ctctgtgaaa ttccctacag agtctcccaa aattcacatc caataaacag 2400

 cctgcagccc cgagtgacat atgtcctgtg gatgacagct ctgacagctg 2450

 ctggtgaaag ttcccacgga aatgagaggg aattttgtct gcaaggtaaa 2500

 gccaattgga tggcgtttgt ggcaccaagc atttgcattg ctatcatcat 2550

 ggtgggcatt ttctcaacgc attacttcca gcaaaaggtg tttgttctcc 2600

 tagcagccct cagacctcag tggtgtagca gagaaattcc agatccagca 2650

 aatagcactt gcgctaagaa atatcccatt gcagaggaga agacacagct 2700

 gcccttggac aggctcctga tagactggcc cacgcctgaa gatcctgaac 2750

 cgctggtcat cagtgaagtc cttcatcaag tgaccccagt tttcagacat 2800

 cccccctgct ccaactggcc acaaagggaa aaaggaatcc aaggtcatca 2850

 ggcctctgag aaagacatga tgcacagtgc ctcaagccca ccacctccaa 2900

 gagctctcca agctgagagc agacaactgg tggatctgta caaggtgctg 2950

 gagagcaggg gctccgaccc aaagcccgaa aacccagcct gtccctggac 3000

 ggtgctccca gcaggtgacc ttcccaccca tgatggctac ttaccctcca 3050

 acatagatga cctcccctca catgaggcac ctctcgctga ctctctggaa 3100

 gaactggagc ctcagcacat ctccctttct gttttcccct caagttctct 3150

 tcacccactc accttctcct gtggtgataa gctgactctg gatcagttaa 3200

 agatgaggtg tgactccctc atgctctgag tggtgaggct tcaagcctta 3250

 aagtcagtgt gccctcaacc agcacagcct gccccaattc ccccagcccc 3300

 tgctccagca gctgtcatct ctgggtgcca ccatcggtct ggctgcagct 3350

 agaggacagg caagccagct ctgggggagt cttaggaact gggagttggt 3400

 cttcactcag atgcctcatc ttgcctttcc cagggcctta aaattacatc 3450

 cttcactgtg tggacctaga gactccaact tgaattccta gtaactttct 3500

 tggtatgctg gccagaaagg gaaatgagga ggagagtaga aaccacagct 3550

 cttagtagta atggcataca gtctagagga ccattcatgc aatgactatt 3600

 tctaaagcac ctgctacaca gcaggctgta cacagcagat cagtactgtt 3650

 caacagaact tcctgagatg atggaaatgt tctacctctg cactcactgt 3700

 ccagtacatt agacactagg cacattggct gttaatcact tggaatgtgt 3750

 ttagcttgac tgaggaatta aattttgatt gtaaatttaa atcgccacac 3800

 atggctagtg gctactgtat tggagtgcac agctctagat ggctcctaga 3850

 ttattgagag ccttcaaaac aaatcaacct agttctatag atgaagacat 3900

 aaaagacact ggtaaacacc aaggtaaaag ggcccccaag gtggtcatga 3950

 ctggtctcat ttgcagaagt ctaagaatgt acctttttct ggccgggcgt 4000

 ggtagctcat gcctgtaatc ccagcacttt gggaggctga 4040

<210> 5386
<211> 862
<212> PRT
<213> Homo sapien

<400> 5386
 Met Ala His Thr Phe Arg Gly Cys Ser Leu Ala Phe Met Phe Ile
   1               5                  10                  15

 Ile Thr Trp Leu Leu Ile Lys Ala Lys Ile Asp Ala Cys Lys Arg
                  20                  25                  30

 Gly Asp Val Thr Val Lys Pro Ser His Val Ile Leu Leu Gly Ser
                  35                  40                  45

 Thr Val Asn Ile Thr Cys Ser Leu Lys Pro Arg Gln Gly Cys Phe
                  50                  55                  60

 His Tyr Ser Arg Arg Asn Lys Leu Ile Leu Tyr Lys Phe Asp Arg
                  65                  70                  75

 Arg Ile Asn Phe His His Gly His Ser Leu Asn Ser Gln Val Thr
                  80                  85                  90

 Gly Leu Pro Leu Gly Thr Thr Leu Phe Val Cys Lys Leu Ala Cys
                  95                 100                 105

 Ile Asn Ser Asp Glu Ile Gln Ile Cys Gly Ala Glu Ile Phe Val
                 110                 115                 120

 Gly Val Ala Pro Glu Gln Pro Gln Asn Leu Ser Cys Ile Gln Lys
                 125                 130                 135

 Gly Glu Gln Gly Thr Val Ala Cys Thr Trp Glu Arg Gly Arg Asp
                 140                 145                 150

 Thr His Leu Tyr Thr Glu Tyr Thr Leu Gln Leu Ser Gly Pro Lys
                 155                 160                 165

 Asn Leu Thr Trp Gln Lys Gln Cys Lys Asp Ile Tyr Cys Asp Tyr
                 170                 175                 180

 Leu Asp Phe Gly Ile Asn Leu Thr Pro Glu Ser Pro Glu Ser Asn
                 185                 190                 195

 Phe Thr Ala Lys Val Thr Ala Val Asn Ser Leu Gly Ser Ser Ser
                 200                 205                 210

 Ser Leu Pro Ser Thr Phe Thr Phe Leu Asp Ile Val Arg Pro Leu
                 215                 220                 225

 Pro Pro Trp Asp Ile Arg Ile Lys Phe Gln Lys Ala Ser Val Ser
                 230                 235                 240

 Arg Cys Thr Leu Tyr Trp Arg Asp Glu Gly Leu Val Leu Leu Asn
                 245                 250                 255

 Arg Leu Arg Tyr Arg Pro Ser Asn Ser Arg Leu Trp Asn Met Val
                 260                 265                 270

 Asn Val Thr Lys Ala Lys Gly Arg His Asp Leu Leu Asp Leu Lys
                 275                 280                 285

 Pro Phe Thr Glu Tyr Glu Phe Gln Ile Ser Ser Lys Leu His Leu
                 290                 295                 300

 Tyr Lys Gly Ser Trp Ser Asp Trp Ser Glu Ser Leu Arg Ala Gln
                 305                 310                 315

 Thr Pro Glu Glu Glu Pro Thr Gly Met Leu Asp Val Trp Tyr Met
                 320                 325                 330

 Lys Arg His Ile Asp Tyr Ser Arg Gln Gln Ile Ser Leu Phe Trp
                 335                 340                 345

 Lys Asn Leu Ser Val Ser Glu Ala Arg Gly Lys Ile Leu His Tyr
                 350                 355                 360

 Gln Val Thr Leu Gln Glu Leu Thr Gly Gly Lys Ala Met Thr Gln
                 365                 370                 375

 Asn Ile Thr Gly His Thr Ser Trp Thr Thr Val Ile Pro Arg Thr
                 380                 385                 390

 Gly Asn Trp Ala Val Ala Val Ser Ala Ala Asn Ser Lys Gly Ser
                 395                 400                 405

 Ser Leu Pro Thr Arg Ile Asn Ile Met Asn Leu Cys Glu Ala Gly
                 410                 415                 420

 Leu Leu Ala Pro Arg Gln Val Ser Ala Asn Ser Glu Gly Met Asp
                 425                 430                 435

 Asn Ile Leu Val Thr Trp Gln Pro Pro Arg Lys Asp Pro Ser Ala
                 440                 445                 450

 Val Gln Glu Tyr Val Val Glu Trp Arg Glu Leu His Pro Gly Gly
                 455                 460                 465

 Asp Thr Gln Val Pro Leu Asn Trp Leu Arg Ser Arg Pro Tyr Asn
                 470                 475                 480

 Val Ser Ala Leu Ile Ser Glu Asn Ile Lys Ser Tyr Ile Cys Tyr
                 485                 490                 495

 Glu Ile Arg Val Tyr Ala Leu Ser Gly Asp Gln Gly Gly Cys Ser
                 500                 505                 510

 Ser Ile Leu Gly Asn Ser Lys His Lys Ala Pro Leu Ser Gly Pro
                 515                 520                 525

 His Ile Asn Ala Ile Thr Glu Glu Lys Gly Ser Ile Leu Ile Ser
                 530                 535                 540

 Trp Asn Ser Ile Pro Val Gln Glu Gln Met Gly Cys Leu Leu His
                 545                 550                 555

 Tyr Arg Ile Tyr Trp Lys Glu Arg Asp Ser Asn Ser Gln Pro Gln
                 560                 565                 570

 Leu Cys Glu Ile Pro Tyr Arg Val Ser Gln Asn Ser His Pro Ile
                 575                 580                 585

 Asn Ser Leu Gln Pro Arg Val Thr Tyr Val Leu Trp Met Thr Ala
                 590                 595                 600

 Leu Thr Ala Ala Gly Glu Ser Ser His Gly Asn Glu Arg Glu Phe
                 605                 610                 615

 Cys Leu Gln Gly Lys Ala Asn Trp Met Ala Phe Val Ala Pro Ser
                 620                 625                 630

 Ile Cys Ile Ala Ile Ile Met Val Gly Ile Phe Ser Thr His Tyr
                 635                 640                 645

 Phe Gln Gln Lys Val Phe Val Leu Leu Ala Ala Leu Arg Pro Gln
                 650                 655                 660

 Trp Cys Ser Arg Glu Ile Pro Asp Pro Ala Asn Ser Thr Cys Ala
                 665                 670                 675

 Lys Lys Tyr Pro Ile Ala Glu Glu Lys Thr Gln Leu Pro Leu Asp
                 680                 685                 690

 Arg Leu Leu Ile Asp Trp Pro Thr Pro Glu Asp Pro Glu Pro Leu
                 695                 700                 705

 Val Ile Ser Glu Val Leu His Gln Val Thr Pro Val Phe Arg His
                 710                 715                 720

 Pro Pro Cys Ser Asn Trp Pro Gln Arg Glu Lys Gly Ile Gln Gly
                 725                 730                 735

 His Gln Ala Ser Glu Lys Asp Met Met His Ser Ala Ser Ser Pro
                 740                 745                 750

 Pro Pro Pro Arg Ala Leu Gln Ala Glu Ser Arg Gln Leu Val Asp
                 755                 760                 765

 Leu Tyr Lys Val Leu Glu Ser Arg Gly Ser Asp Pro Lys Pro Glu
                 770                 775                 780

 Asn Pro Ala Cys Pro Trp Thr Val Leu Pro Ala Gly Asp Leu Pro
                 785                 790                 795

 Thr His Asp Gly Tyr Leu Pro Ser Asn Ile Asp Asp Leu Pro Ser
                 800                 805                 810

 His Glu Ala Pro Leu Ala Asp Ser Leu Glu Glu Leu Glu Pro Gln
                 815                 820                 825

 His Ile Ser Leu Ser Val Phe Pro Ser Ser Ser Leu His Pro Leu
                 830                 835                 840

 Thr Phe Ser Cys Gly Asp Lys Leu Thr Leu Asp Gln Leu Lys Met
                 845                 850                 855

 Arg Cys Asp Ser Leu Met Leu
                 860

<210> 5387
<211> 1419
<212> DNA
<213> Homo sapien

<400> 5387
 ccacgcgtcc gagaccaagg agtggaaagt tctccggcag ccctgagatc 50

 tcaagagtga catttgtgag accagctaat ttgattaaaa ttctcttgga 100

 atcagctttg ctagtatcat acctgtcgca gatttcatca tgggaaacag 150

 ctgttacaac atagtagcca ctctgttgct ggtcctcaac tttgagagga 200

 caagatcatt gcaggatcct tgtagtaact gcccagctgg tacattctgt 250

 gataataaca ggaatcagat ttgcagtccc tgtcctccaa atagtttctc 300

 cagcgcaggt ggacaaagga cctgtgacat atgcaggcag tgtaaaggtg 350

 ttttcaggac caggaaggag tgttcctcca ccagcaatgc agagtgtgac 400

 tgcactccag ggtttcactg cctgggggca ggatgcagca tgtgtgaaca 450

 ggattgtaaa caaggtcaag aactgacaaa aaaaggttgt aaagactgtt 500

 gctttgggac atttaacgat cagaaacgtg gcatctgtcg accctggaca 550

 aactgttctt tggatggaaa gtctgtgctt gtgaatggga cgaaggagag 600

 ggacgtggtc tgtggaccat ctccagccga cctctctccg ggagcatcct 650

 ctgtgacccc gcctgcccct gcgagagagc caggacactc tccgcagatc 700

 atctccttct ttcttgcgct gacgtcgact gcgttgctct tcctgctgtt 750

 cttcctcacg ctccgtttct ctgttgttaa acggggcaga aagaaactcc 800

 tgtatatatt caaacaacca tttatgagac cagtacaaac tactcaagag 850

 gaagatggct gtagctgccg atttccagaa gaagaagaag gaggatgtga 900

 actgtgaaat ggaagtcaat agggctgttg ggactttctt gaaaagaagc 950

 aaggaaatat gagtcatccg ctatcacagc tttcaaaagc aagaacacca 1000

 tcctacataa tacccaggat tcccccaaca cacgttcttt tctaaatgcc 1050

 aatgagttgg cctttaaaaa tgcaccactt tttttttttt tttggacagg 1100

 gtctcactct gtcacccagg ctggagtgca gtggcaccac catggctctc 1150

 tgcagccttg acctctggga gctcaagtga tcctcctgcc tcagtctcct 1200

 gagtagctgg aactacaagg aagggccacc acacctgact aacttttttg 1250

 ttttttgttg gtaaagatgg catttcgcca tgttgtacag gctggtctca 1300

 aactcctagg ttcactttgg cctcccaaag tgctgggatt acagacatga 1350

 actgccaggc ccggccaaaa taatgcacca cttttaacag aacagacaga 1400

 tgaggacaga gctggtgat 1419

<210> 5388
<211> 255
<212> PRT
<213> Homo sapien

<400> 5388
 Met Gly Asn Ser Cys Tyr Asn Ile Val Ala Thr Leu Leu Leu Val
   1               5                  10                  15

 Leu Asn Phe Glu Arg Thr Arg Ser Leu Gln Asp Pro Cys Ser Asn
                  20                  25                  30

 Cys Pro Ala Gly Thr Phe Cys Asp Asn Asn Arg Asn Gln Ile Cys
                  35                  40                  45

 Ser Pro Cys Pro Pro Asn Ser Phe Ser Ser Ala Gly Gly Gln Arg
                  50                  55                  60

 Thr Cys Asp Ile Cys Arg Gln Cys Lys Gly Val Phe Arg Thr Arg
                  65                  70                  75

 Lys Glu Cys Ser Ser Thr Ser Asn Ala Glu Cys Asp Cys Thr Pro
                  80                  85                  90

 Gly Phe His Cys Leu Gly Ala Gly Cys Ser Met Cys Glu Gln Asp
                  95                 100                 105

 Cys Lys Gln Gly Gln Glu Leu Thr Lys Lys Gly Cys Lys Asp Cys
                 110                 115                 120

 Cys Phe Gly Thr Phe Asn Asp Gln Lys Arg Gly Ile Cys Arg Pro
                 125                 130                 135

 Trp Thr Asn Cys Ser Leu Asp Gly Lys Ser Val Leu Val Asn Gly
                 140                 145                 150

 Thr Lys Glu Arg Asp Val Val Cys Gly Pro Ser Pro Ala Asp Leu
                 155                 160                 165

 Ser Pro Gly Ala Ser Ser Val Thr Pro Pro Ala Pro Ala Arg Glu
                 170                 175                 180

 Pro Gly His Ser Pro Gln Ile Ile Ser Phe Phe Leu Ala Leu Thr
                 185                 190                 195

 Ser Thr Ala Leu Leu Phe Leu Leu Phe Phe Leu Thr Leu Arg Phe
                 200                 205                 210

 Ser Val Val Lys Arg Gly Arg Lys Lys Leu Leu Tyr Ile Phe Lys
                 215                 220                 225

 Gln Pro Phe Met Arg Pro Val Gln Thr Thr Gln Glu Glu Asp Gly
                 230                 235                 240

 Cys Ser Cys Arg Phe Pro Glu Glu Glu Glu Gly Gly Cys Glu Leu
                 245                 250                 255

<210> 5389
<211> 1172
<212> DNA
<213> Homo sapien

<400> 5389
 gagacattcc tcaattgctt agacatattc tgagcctaca gcagaggaac 50

 ctccagtctc agcaccatga atcaaactgc gattctgatt tgctgcctta 100

 tctttctgac tctaagtggc attcaaggag tacctctctc tagaaccgta 150

 cgctgtacct gcatcagcat tagtaatcaa cctgttaatc caaggtcttt 200

 agaaaaactt gaaattattc ctgcaagcca attttgtcca cgtgttgaga 250

 tcattgctac aatgaaaaag aagggtgaga agagatgtct gaatccagaa 300

 tcgaaggcca tcaagaattt actgaaagca gttagcaagg aaatgtctaa 350

 aagatctcct taaaaccaga ggggagcaaa atcgatgcag tgcttccaag 400

 gatggaccac acagaggctg cctctcccat cacttcccta catggagtat 450

 atgtcaagcc ataattgttc ttagtttgca gttacactaa aaggtgacca 500

 atgatggtca ccaaatcagc tgctactact cctgtaggaa ggttaatgtt 550

 catcatccta agctattcag taataactct accctggcac tataatgtaa 600

 gctctactga ggtgctatgt tcttagtgga tgttctgacc ctgcttcaaa 650

 tatttccctc acctttccca tcttccaagg gtactaagga atctttctgc 700

 tttggggttt atcagaattc tcagaatctc aaataactaa aaggtatgca 750

 atcaaatctg ctttttaaag aatgctcttt acttcatgga cttccactgc 800

 catcctccca aggggcccaa attctttcag tggctaccta catacaattc 850

 caaacacata caggaaggta gaaatatctg aaaatgtatg tgtaagtatt 900

 cttatttaat gaaagactgt acaaagtata agtcttagat gtatatattt 950

 cctatattgt tttcagtgta catggaataa catgtaatta agtactatgt 1000

 atcaatgagt aacaggaaaa ttttaaaaat acagatagat atatgctctg 1050

 catgttacat aagataaatg tgctgaatgg ttttcaaata aaaatgaggt 1100

 actctcctgg aaatattaag aaagactatc taaatgttga aagatcaaaa 1150

 ggttaataaa gtaattataa ct 1172

<210> 5390
<211> 98
<212> PRT
<213> Homo sapien

<400> 5390
 Met Asn Gln Thr Ala Ile Leu Ile Cys Cys Leu Ile Phe Leu Thr
   1               5                  10                  15

 Leu Ser Gly Ile Gln Gly Val Pro Leu Ser Arg Thr Val Arg Cys
                  20                  25                  30

 Thr Cys Ile Ser Ile Ser Asn Gln Pro Val Asn Pro Arg Ser Leu
                  35                  40                  45

 Glu Lys Leu Glu Ile Ile Pro Ala Ser Gln Phe Cys Pro Arg Val
                  50                  55                  60

 Glu Ile Ile Ala Thr Met Lys Lys Lys Gly Glu Lys Arg Cys Leu
                  65                  70                  75

 Asn Pro Glu Ser Lys Ala Ile Lys Asn Leu Leu Lys Ala Val Ser
                  80                  85                  90

 Lys Glu Met Ser Lys Arg Ser Pro
                  95

<210> 5391
<211> 5496
<212> DNA
<213> Homo sapien

<400> 5391
 attcagccgg tgcgcgcggc ggcgggaggc agtggctggg gagtcccgtc 50

 gacgctctgt tccgagagcg tgccccggac cgccagctca gaacaggggc 100

 agccgtgtag ccgaacggaa gctgggagca gccgggactg gtggcccgcg 150

 cccgagctcc gcaggcggga agcaccctgg atttgggaag tcccgggagc 200

 agcgcggcgg cacctccctc acccaagggg ccgcggcgac ggtcacgggg 250

 cgcggcgcca ccgtgagcga cccaggccag gattctaaat agacggccca 300

 ggctcctcct ccgcccgggc cgcctcacct gcgggcattg ccgcgccgcc 350

 tccgccggtg tagacggcac ctgcgccgcc ttgctcgcgg gtctccgccc 400

 ctcgcccacc ctcactgcgc caggcccagg cagctcacct gtactggcgc 450

 gggctgcgga agcctgcgtg agccgaggcg ttgaggcgcg gcgcccacgc 500

 cactgtcccg agaggacgca ggtggagcgg gcgcggcttc gcggaacccg 550

 gcgccggccg ccgcagtggt cccagcctac accgggttcc ggggacccgg 600

 ccgccagtgc ccggggagta gccgccgccg tcggctgggc accatgaaca 650

 gcagcagcgc caacatcacc tacgccagtc gcaagcggcg gaagccggtg 700

 cagaaaacag taaagccaat cccagctgaa ggaatcaagt caaatccttc 750

 caagcggcat agagaccgac ttaatacaga gttggaccgt ttggctagcc 800

 tgctgccttt cccacaagat gttattaata agttggacaa actttcagtt 850

 cttaggctca gcgtcagtta cctgagagcc aagagcttct ttgatgttgc 900

 attaaaatcc tcccctactg aaagaaacgg aggccaggat aactgtagag 950

 cagcaaattt cagagaaggc ctgaacttac aagaaggaga attcttatta 1000

 caggctctga atggctttgt attagttgtc actacagatg ctttggtctt 1050

 ttatgcttct tctactatac aagattatct agggtttcag cagtctgatg 1100

 tcatacatca gagtgtatat gaacttatcc ataccgaaga ccgagctgaa 1150

 tttcagcgtc agctacactg ggcattaaat ccttctcagt gtacagagtc 1200

 tggacaagga attgaagaag ccactggtct cccccagaca gtagtctgtt 1250

 ataacccaga ccagattcct ccagaaaact ctcctttaat ggagaggtgc 1300

 ttcatatgtc gtctaaggtg tctgctggat aattcatctg gttttctggc 1350

 aatgaatttc caagggaagt taaagtatct tcatggacag aaaaagaaag 1400

 ggaaagatgg atcaatactt ccacctcagt tggctttgtt tgcgatagct 1450

 actccacttc agccaccatc catacttgaa atccggacca aaaattttat 1500

 ctttagaacc aaacacaaac tagacttcac acctattggt tgtgatgcca 1550

 aaggaagaat tgttttagga tatactgaag cagagctgtg cacgagaggc 1600

 tcaggttatc agtttattca tgcagctgat atgctttatt gtgccgagtc 1650

 ccatatccga atgattaaga ctggagaaag tggcatgata gttttccggc 1700

 ttcttacaaa aaacaaccga tggacttggg tccagtctaa tgcacgcctg 1750

 ctttataaaa atggaagacc agattatatc attgtaactc agagaccact 1800

 aacagatgag gaaggaacag agcatttacg aaaacgaaat acgaagttgc 1850

 cttttatgtt taccactgga gaagctgtgt tgtatgaggc aaccaaccct 1900

 tttcctgcca taatggatcc cttaccacta aggactaaaa atggcactag 1950

 tggaaaagac tctgctacca catccactct aagcaaggac tctctcaatc 2000

 ctagttccct cctggctgcc atgatgcaac aagatgagtc tatttatctc 2050

 tatcctgctt caagtacttc aagtactgca ccttttgaaa acaacttttt 2100

 caacgaatct atgaatgaat gcagaaattg gcaagataat actgcaccga 2150

 tgggaaatga tactatcctg aaacatgagc aaattgacca gcctcaggat 2200

 gtgaactcat ttgctggagg tcacccaggg ctctttcaag atagtaaaaa 2250

 cagtgacttg tacagcataa tgaaaaacct aggcattgat tttgaagaca 2300

 tcagacacat gcagaatgaa aaatttttca gaaatgattt ttctggtgag 2350

 gttgacttca gagacattga cttaacggat gaaatcctga cgtatgtcca 2400

 agattcttta agtaagtctc ccttcatacc ttcagattat caacagcaac 2450

 agtccttggc tctgaactca agctgtatgg tacaggaaca cctacatcta 2500

 gaacagcaac agcaacatca ccaaaagcaa gtagtagtgg agccacagca 2550

 acagctgtgt cagaagatga agcacatgca agttaatggc atgtttgaaa 2600

 attggaactc taaccaattc gtgcctttca attgtccaca gcaagaccca 2650

 caacaatata atgtctttac agacttacat gggatcagtc aagagttccc 2700

 ctacaaatct gaaatggatt ctatgcctta tacacagaac tttatttcct 2750

 gtaatcagcc tgtattacca caacattcca aatgtacaga gctggactac 2800

 cctatgggga gttttgaacc atccccatac cccactactt ctagtttaga 2850

 agattttgtc acttgtttac aacttcctga aaaccaaaag catggattaa 2900

 atccacagtc agccataata actcctcaga catgttatgc tggggccgtg 2950

 tcgatgtatc agtgccagcc agaacctcag cacacccacg tgggtcagat 3000

 gcagtacaat ccagtactgc caggccaaca ggcattttta aacaagtttc 3050

 agaatggagt tttaaatgaa acatatccag ctgaattaaa taacataaat 3100

 aacactcaga ctaccacaca tcttcagcca cttcatcatc cgtcagaagc 3150

 cagacctttt cctgatttga catccagtgg attcctgtaa ttccaagccc 3200

 aattttgacc ctggtttttg gattaaatta gtttgtgaag gattatggaa 3250

 aaataaaact gtcactgttg gacgtcagca agttcacatg gaggcattga 3300

 tgcatgctat tcacaattat tccaaaccaa attttaattt ttgcttttag 3350

 aaaagggagt ttaaaaatgg tatcaaaatt acatatacta cagtcaagat 3400

 agaaagggtg ctgccacgga gtggtgaggt accgtctaca tttcacatta 3450

 ttctgggcac cacaaaatat acaaaacttt atcagggaaa ctaagattct 3500

 tttaaattag aaaatattct ctatttgaat tatttctgtc acagtaaaaa 3550

 taaaatactt tgagttttga gctactggat tcttattagt tccccaaata 3600

 caaagttaga gaactaaact agtttttcct atcatgttaa cctctgcttt 3650

 tatctcagat gttaaaataa atggtttggt gctttttata aaaagataat 3700

 ctcagtgctt tcctccttca ctgtttcatc taagtgcctc acattttttt 3750

 ctacctataa cactctagga tgtatatttt atataaagta ttctttttct 3800

 tttttaaatt aatatctttc tgcacacaaa tattatttgt gtttcctaaa 3850

 tccaaccaat tttcattaat tcaggcatat tttaactcca ctgcttacct 3900

 actttcttca ggtaaaaggg caaataatga tcgaaaaaat aattatttat 3950

 tacataattt agttgtttct agactataaa tgttgctatg tgccttatgt 4000

 tgaaaaaatt taaaagtaaa atgtctttcc aaattatttc ttaattatta 4050

 taaaaatatt aagacaatag cacttaaatt cctcaacagt gttttcagaa 4100

 gaaataaata taccactctt tacctttatt gatatctcca tgatgatagt 4150

 tgaatgttgc aatgtgaaaa atctgctgtt aactgcaacc ttgtttatta 4200

 aattgcaaga agctttattt ctagcttttt aattaagcaa agcacccatt 4250

 tcaatgtgta taaattgtct ttaaaaactg ttttagacct ataatccttg 4300

 ataatatatt gtgttgactt tataaatttc gcttcttaga acagtggaaa 4350

 ctatgtgttt ttctcatatt tgaggagtgt taagattgca gatagcaagg 4400

 tttggtgcaa agtattgtaa tgagtgaatt gaatggtgca ttgtatagat 4450

 ataatgaaca aaattatttg taagatattt gcagtttttc attttaaaaa 4500

 gtccatacct tatatatgca cttaatttgt tggggcttta catactttat 4550

 caatgtgtct ttctaagaaa tcaagtaatg aatccaactg cttaaagttg 4600

 gtattaataa aaagacaacc acatagttcg tttaccttca aactttaggt 4650

 ttttttaatg atatactgat cttcattacc aataggcaaa ttaatcaccc 4700

 taccaacttt actgtcctaa catggacttt caaaaagaaa aaatgacacc 4750

 atcttttatt cttttttttt tttttttttt gagagagagt cttactctgc 4800

 cgcccaaact ggagtgcagt ggcacaatct tggctcactg caacctctac 4850

 ctcctgggtt caagtgattc tcttgcctca gcctcccgag ttgctgggat 4900

 tgcgggcatg gtggcgtgag cctgtagtcc tagctactcg ggaggctgag 4950

 gcaggagaat agcctgaacc tgggaatcgg aggttgcagg gccaagatcg 5000

 ccccactgca ctccagcctg gcaatagacc gagctccgtc tccaaaaaaa 5050

 aaaatacaat ttttatttct tttacttttt ttagtaagtt aatgtatata 5100

 aaaatggctt cggacaaaat atctctgagt tctgtgtatt ttcagtcaaa 5150

 actttaaacc tgtagaatca atttaagtgt tgaaaaaaat ttgtctgaaa 5200

 catttcataa tttgtttcca gcatgaggta tctaaggatt tagaccagag 5250

 gtctagatta atactctatt tttacattta aaccttttat tataagtctt 5300

 acataaacca tttttgttac tctcttccac atgttactgg ataaattgtt 5350

 tagtggaaaa taggcttttt aatcatgaat atgatgacaa tcagttatac 5400

 agttataaaa ttaaaagttt gaaaagcaat attgtatatt tttatctata 5450

 taaaataact aaaatgtatc taagaataat aaaatcacgt taaacc 5496

<210> 5392
<211> 848
<212> PRT
<213> Homo sapien

<400> 5392
 Met Asn Ser Ser Ser Ala Asn Ile Thr Tyr Ala Ser Arg Lys Arg
   1               5                  10                  15

 Arg Lys Pro Val Gln Lys Thr Val Lys Pro Ile Pro Ala Glu Gly
                  20                  25                  30

 Ile Lys Ser Asn Pro Ser Lys Arg His Arg Asp Arg Leu Asn Thr
                  35                  40                  45

 Glu Leu Asp Arg Leu Ala Ser Leu Leu Pro Phe Pro Gln Asp Val
                  50                  55                  60

 Ile Asn Lys Leu Asp Lys Leu Ser Val Leu Arg Leu Ser Val Ser
                  65                  70                  75

 Tyr Leu Arg Ala Lys Ser Phe Phe Asp Val Ala Leu Lys Ser Ser
                  80                  85                  90

 Pro Thr Glu Arg Asn Gly Gly Gln Asp Asn Cys Arg Ala Ala Asn
                  95                 100                 105

 Phe Arg Glu Gly Leu Asn Leu Gln Glu Gly Glu Phe Leu Leu Gln
                 110                 115                 120

 Ala Leu Asn Gly Phe Val Leu Val Val Thr Thr Asp Ala Leu Val
                 125                 130                 135

 Phe Tyr Ala Ser Ser Thr Ile Gln Asp Tyr Leu Gly Phe Gln Gln
                 140                 145                 150

 Ser Asp Val Ile His Gln Ser Val Tyr Glu Leu Ile His Thr Glu
                 155                 160                 165

 Asp Arg Ala Glu Phe Gln Arg Gln Leu His Trp Ala Leu Asn Pro
                 170                 175                 180

 Ser Gln Cys Thr Glu Ser Gly Gln Gly Ile Glu Glu Ala Thr Gly
                 185                 190                 195

 Leu Pro Gln Thr Val Val Cys Tyr Asn Pro Asp Gln Ile Pro Pro
                 200                 205                 210

 Glu Asn Ser Pro Leu Met Glu Arg Cys Phe Ile Cys Arg Leu Arg
                 215                 220                 225

 Cys Leu Leu Asp Asn Ser Ser Gly Phe Leu Ala Met Asn Phe Gln
                 230                 235                 240

 Gly Lys Leu Lys Tyr Leu His Gly Gln Lys Lys Lys Gly Lys Asp
                 245                 250                 255

 Gly Ser Ile Leu Pro Pro Gln Leu Ala Leu Phe Ala Ile Ala Thr
                 260                 265                 270

 Pro Leu Gln Pro Pro Ser Ile Leu Glu Ile Arg Thr Lys Asn Phe
                 275                 280                 285

 Ile Phe Arg Thr Lys His Lys Leu Asp Phe Thr Pro Ile Gly Cys
                 290                 295                 300

 Asp Ala Lys Gly Arg Ile Val Leu Gly Tyr Thr Glu Ala Glu Leu
                 305                 310                 315

 Cys Thr Arg Gly Ser Gly Tyr Gln Phe Ile His Ala Ala Asp Met
                 320                 325                 330

 Leu Tyr Cys Ala Glu Ser His Ile Arg Met Ile Lys Thr Gly Glu
                 335                 340                 345

 Ser Gly Met Ile Val Phe Arg Leu Leu Thr Lys Asn Asn Arg Trp
                 350                 355                 360

 Thr Trp Val Gln Ser Asn Ala Arg Leu Leu Tyr Lys Asn Gly Arg
                 365                 370                 375

 Pro Asp Tyr Ile Ile Val Thr Gln Arg Pro Leu Thr Asp Glu Glu
                 380                 385                 390

 Gly Thr Glu His Leu Arg Lys Arg Asn Thr Lys Leu Pro Phe Met
                 395                 400                 405

 Phe Thr Thr Gly Glu Ala Val Leu Tyr Glu Ala Thr Asn Pro Phe
                 410                 415                 420

 Pro Ala Ile Met Asp Pro Leu Pro Leu Arg Thr Lys Asn Gly Thr
                 425                 430                 435

 Ser Gly Lys Asp Ser Ala Thr Thr Ser Thr Leu Ser Lys Asp Ser
                 440                 445                 450

 Leu Asn Pro Ser Ser Leu Leu Ala Ala Met Met Gln Gln Asp Glu
                 455                 460                 465

 Ser Ile Tyr Leu Tyr Pro Ala Ser Ser Thr Ser Ser Thr Ala Pro
                 470                 475                 480

 Phe Glu Asn Asn Phe Phe Asn Glu Ser Met Asn Glu Cys Arg Asn
                 485                 490                 495

 Trp Gln Asp Asn Thr Ala Pro Met Gly Asn Asp Thr Ile Leu Lys
                 500                 505                 510

 His Glu Gln Ile Asp Gln Pro Gln Asp Val Asn Ser Phe Ala Gly
                 515                 520                 525

 Gly His Pro Gly Leu Phe Gln Asp Ser Lys Asn Ser Asp Leu Tyr
                 530                 535                 540

 Ser Ile Met Lys Asn Leu Gly Ile Asp Phe Glu Asp Ile Arg His
                 545                 550                 555

 Met Gln Asn Glu Lys Phe Phe Arg Asn Asp Phe Ser Gly Glu Val
                 560                 565                 570

 Asp Phe Arg Asp Ile Asp Leu Thr Asp Glu Ile Leu Thr Tyr Val
                 575                 580                 585

 Gln Asp Ser Leu Ser Lys Ser Pro Phe Ile Pro Ser Asp Tyr Gln
                 590                 595                 600

 Gln Gln Gln Ser Leu Ala Leu Asn Ser Ser Cys Met Val Gln Glu
                 605                 610                 615

 His Leu His Leu Glu Gln Gln Gln Gln His His Gln Lys Gln Val
                 620                 625                 630

 Val Val Glu Pro Gln Gln Gln Leu Cys Gln Lys Met Lys His Met
                 635                 640                 645

 Gln Val Asn Gly Met Phe Glu Asn Trp Asn Ser Asn Gln Phe Val
                 650                 655                 660

 Pro Phe Asn Cys Pro Gln Gln Asp Pro Gln Gln Tyr Asn Val Phe
                 665                 670                 675

 Thr Asp Leu His Gly Ile Ser Gln Glu Phe Pro Tyr Lys Ser Glu
                 680                 685                 690

 Met Asp Ser Met Pro Tyr Thr Gln Asn Phe Ile Ser Cys Asn Gln
                 695                 700                 705

 Pro Val Leu Pro Gln His Ser Lys Cys Thr Glu Leu Asp Tyr Pro
                 710                 715                 720

 Met Gly Ser Phe Glu Pro Ser Pro Tyr Pro Thr Thr Ser Ser Leu
                 725                 730                 735

 Glu Asp Phe Val Thr Cys Leu Gln Leu Pro Glu Asn Gln Lys His
                 740                 745                 750

 Gly Leu Asn Pro Gln Ser Ala Ile Ile Thr Pro Gln Thr Cys Tyr
                 755                 760                 765

 Ala Gly Ala Val Ser Met Tyr Gln Cys Gln Pro Glu Pro Gln His
                 770                 775                 780

 Thr His Val Gly Gln Met Gln Tyr Asn Pro Val Leu Pro Gly Gln
                 785                 790                 795

 Gln Ala Phe Leu Asn Lys Phe Gln Asn Gly Val Leu Asn Glu Thr
                 800                 805                 810

 Tyr Pro Ala Glu Leu Asn Asn Ile Asn Asn Thr Gln Thr Thr Thr
                 815                 820                 825

 His Leu Gln Pro Leu His His Pro Ser Glu Ala Arg Pro Phe Pro
                 830                 835                 840

 Asp Leu Thr Ser Ser Gly Phe Leu
                 845

<210> 5393
<211> 2254
<212> DNA
<213> Homo sapien

<400> 5393
 aaagaaccgc acaccacaga ctccctccag ctctttgtgt gtggctctct 50

 cagggtccaa caagagcaag ctgtgggtct gtgagtgttt atgtgtgctt 100

 ttattcactt cacacttatt gaaaagtgtg tatgtgagag ggtggggtgt 150

 gtgtgtcaaa gagagtgagg aagagaagga gagagagatc aattgattct 200

 gcagcctcag ctccagcatc cctcagttgg gagcttccaa agccgggtga 250

 tcacttgggg tgcatagctc ggagatgcag tccccctgga aaatccttac 300

 ggtggcgcct ctattcttgc tcctgtctct tcagtcctcg gcctctccag 350

 ccaacgatga ccagtccagg cccagcctct cgaatgggca cacctgtgta 400

 gggtgtgtgc tggtggtgtc tgtaatagaa cagcttgctc aagttcacaa 450

 ctcgacggtc caggcctcga tggagagact gtgcagctac ctgcctgaaa 500

 aactgttctt gaaaaccacc tgctatttag tcattgacaa gtttggatca 550

 gacatcataa aactgcttag cgcagatatg aatgctgatg tggtatgtca 600

 cactctggag ttttgtaaac agaacactgg ccaaccattg tgtcatctct 650

 accctcttcc caaggagaca tggaaattta cactacagaa ggcaagacaa 700

 attgtcaaga agtccccgat tctgaaatat tctagaagtg gttctgacat 750

 ttgttcactc ccggttttgg ccaagatctg ccagaaaatt aaattagcta 800

 tggaacagtc tgtgccattc aaagatgtgg attcagacaa atacagcgtt 850

 ttcccaacac tgcggggcta tcactggcgg gggagagact gtaatgacag 900

 cgacgagtca gtgtacccag gtagaaggcc gaacaactgg gatgtccatc 950

 aggattcaaa ctgtaatggc atttggggtg tcgatccaaa agatggagtt 1000

 ccatatgaga agaaattctg tgaaggttca cagcccaggg gaatcatttt 1050

 gctgggagac tcagctgggg ctcattttca catctctcct gaatggatca 1100

 cagcgtcgca gatgtctttg aactctttca tcaatctacc aacagccctt 1150

 accaacgagc ttgactggcc ccaactctct ggtgctacag gatttctgga 1200

 ctccactgtt ggaattaaag aaaaatctat ttaccttcgc ttatggaaaa 1250

 gaaaccactg taatcacagg gactaccaga atatttcaag aaatggtgca 1300

 tcttcccgaa acctgaagaa atttatagaa agcttgtcta gaaacaaggt 1350

 gttggactat cccgccatcg ttatatatgc catgattgga aatgatgtct 1400

 gcagtgggaa gagtgaccca gtcccagcca tgaccactcc tgagaaactc 1450

 tactccaacg tcatgcagac tctgaagcat ctaaattccc acctgcccaa 1500

 tggcagccat gttattttgt atggcttacc agatggaacc tttctctggg 1550

 ataatttgca caacagatat catcctctcg gccagctaaa taaagacatg 1600

 acctatgcgc agttgtactc cttcctgaac tgcctccagg tcagcccctg 1650

 ccacggctgg atgtcttcca acaagacgtt gcggactctc acttcagaga 1700

 gagcagagca actctccaac acactgaaaa aaattgcagc cagtgagaaa 1750

 tttacaaact tcaatctttt ctacatggat tttgccttcc atgaaatcat 1800

 acaggagtgg cagaagagag gcggacagcc ctggcagctc atcgagcccg 1850

 tggatggatt ccaccccaac gaggtggctt tgctgttgtt ggcggatcat 1900

 ttctggaaaa aggtgcagct ccagtggccc caaatcctgg gaaaggagaa 1950

 tccgttcaac ccccagatta aacaggtgtt tggagaccaa ggcgggcact 2000

 gagcctctca ggagcatgca cccctgggga gcacagggag gcagaggctt 2050

 gggtaaactc attccacaaa ccctatgggg gctgccacgt cacaggccca 2100

 aaggactctt cttcagcagc atctttgcaa aatgtctttc tctcaatgaa 2150

 gagcatatct ggacgactgt gcaatgctgt gtgctcccgg ggatcagtaa 2200

 cccttccgct gttcctgaaa taacctttca taaagtgctt tgggtgccat 2250

 tcca 2254

<210> 5394
<211> 575
<212> PRT
<213> Homo sapien

<400> 5394
 Met Gln Ser Pro Trp Lys Ile Leu Thr Val Ala Pro Leu Phe Leu
   1               5                  10                  15

 Leu Leu Ser Leu Gln Ser Ser Ala Ser Pro Ala Asn Asp Asp Gln
                  20                  25                  30

 Ser Arg Pro Ser Leu Ser Asn Gly His Thr Cys Val Gly Cys Val
                  35                  40                  45

 Leu Val Val Ser Val Ile Glu Gln Leu Ala Gln Val His Asn Ser
                  50                  55                  60

 Thr Val Gln Ala Ser Met Glu Arg Leu Cys Ser Tyr Leu Pro Glu
                  65                  70                  75

 Lys Leu Phe Leu Lys Thr Thr Cys Tyr Leu Val Ile Asp Lys Phe
                  80                  85                  90

 Gly Ser Asp Ile Ile Lys Leu Leu Ser Ala Asp Met Asn Ala Asp
                  95                 100                 105

 Val Val Cys His Thr Leu Glu Phe Cys Lys Gln Asn Thr Gly Gln
                 110                 115                 120

 Pro Leu Cys His Leu Tyr Pro Leu Pro Lys Glu Thr Trp Lys Phe
                 125                 130                 135

 Thr Leu Gln Lys Ala Arg Gln Ile Val Lys Lys Ser Pro Ile Leu
                 140                 145                 150

 Lys Tyr Ser Arg Ser Gly Ser Asp Ile Cys Ser Leu Pro Val Leu
                 155                 160                 165

 Ala Lys Ile Cys Gln Lys Ile Lys Leu Ala Met Glu Gln Ser Val
                 170                 175                 180

 Pro Phe Lys Asp Val Asp Ser Asp Lys Tyr Ser Val Phe Pro Thr
                 185                 190                 195

 Leu Arg Gly Tyr His Trp Arg Gly Arg Asp Cys Asn Asp Ser Asp
                 200                 205                 210

 Glu Ser Val Tyr Pro Gly Arg Arg Pro Asn Asn Trp Asp Val His
                 215                 220                 225

 Gln Asp Ser Asn Cys Asn Gly Ile Trp Gly Val Asp Pro Lys Asp
                 230                 235                 240

 Gly Val Pro Tyr Glu Lys Lys Phe Cys Glu Gly Ser Gln Pro Arg
                 245                 250                 255

 Gly Ile Ile Leu Leu Gly Asp Ser Ala Gly Ala His Phe His Ile
                 260                 265                 270

 Ser Pro Glu Trp Ile Thr Ala Ser Gln Met Ser Leu Asn Ser Phe
                 275                 280                 285

 Ile Asn Leu Pro Thr Ala Leu Thr Asn Glu Leu Asp Trp Pro Gln
                 290                 295                 300

 Leu Ser Gly Ala Thr Gly Phe Leu Asp Ser Thr Val Gly Ile Lys
                 305                 310                 315

 Glu Lys Ser Ile Tyr Leu Arg Leu Trp Lys Arg Asn His Cys Asn
                 320                 325                 330

 His Arg Asp Tyr Gln Asn Ile Ser Arg Asn Gly Ala Ser Ser Arg
                 335                 340                 345

 Asn Leu Lys Lys Phe Ile Glu Ser Leu Ser Arg Asn Lys Val Leu
                 350                 355                 360

 Asp Tyr Pro Ala Ile Val Ile Tyr Ala Met Ile Gly Asn Asp Val
                 365                 370                 375

 Cys Ser Gly Lys Ser Asp Pro Val Pro Ala Met Thr Thr Pro Glu
                 380                 385                 390

 Lys Leu Tyr Ser Asn Val Met Gln Thr Leu Lys His Leu Asn Ser
                 395                 400                 405

 His Leu Pro Asn Gly Ser His Val Ile Leu Tyr Gly Leu Pro Asp
                 410                 415                 420

 Gly Thr Phe Leu Trp Asp Asn Leu His Asn Arg Tyr His Pro Leu
                 425                 430                 435

 Gly Gln Leu Asn Lys Asp Met Thr Tyr Ala Gln Leu Tyr Ser Phe
                 440                 445                 450

 Leu Asn Cys Leu Gln Val Ser Pro Cys His Gly Trp Met Ser Ser
                 455                 460                 465

 Asn Lys Thr Leu Arg Thr Leu Thr Ser Glu Arg Ala Glu Gln Leu
                 470                 475                 480

 Ser Asn Thr Leu Lys Lys Ile Ala Ala Ser Glu Lys Phe Thr Asn
                 485                 490                 495

 Phe Asn Leu Phe Tyr Met Asp Phe Ala Phe His Glu Ile Ile Gln
                 500                 505                 510

 Glu Trp Gln Lys Arg Gly Gly Gln Pro Trp Gln Leu Ile Glu Pro
                 515                 520                 525

 Val Asp Gly Phe His Pro Asn Glu Val Ala Leu Leu Leu Leu Ala
                 530                 535                 540

 Asp His Phe Trp Lys Lys Val Gln Leu Gln Trp Pro Gln Ile Leu
                 545                 550                 555

 Gly Lys Glu Asn Pro Phe Asn Pro Gln Ile Lys Gln Val Phe Gly
                 560                 565                 570

 Asp Gln Gly Gly His
                 575

<210> 5395
<211> 3536
<212> DNA
<213> Mus musculus

<400> 5395
 ggcccctcga gcctcgaacc ggaacctcca aatccgagac gctctgctta 50

 tgaggacctc gaaatatgcc ggccagtgaa aaaatcttat ggctttgagg 100

 gcttttggtt ggccaggggc agtaaaaatc tcggagagct gacaccaagt 150

 cctcccctgc cacgtagcag tggtaaagtc cgaagctcaa attccgagaa 200

 ttgagctctg ttgattctta gaactggggt tcttagaagt ggtgatgcaa 250

 gaagtttcta ggaaaggccg gacaccaggt tttgagcaaa attttggact 300

 gtgaagcaag gcattggtga agacaaaatg gcctcgccgg ctgacagctg 350

 tatccagttc acccgccatg ccagtgatgt tcttctcaac cttaatcgtc 400

 tccggagtcg agacatcttg actgatgttg tcattgttgt gagccgtgag 450

 cagtttagag cccataaaac ggtcctcatg gcctgcagtg gcctgttcta 500

 tagcatcttt acagaccagt tgaaatgcaa ccttagtgtg atcaatctag 550

 atcctgagat caaccctgag ggattctgca tcctcctgga cttcatgtac 600

 acatctcggc tcaatttgcg ggagggcaac atcatggctg tgatggccac 650

 ggctatgtac ctgcagatgg agcatgttgt ggacacttgc cggaagttta 700

 ttaaggccag tgaagcagag atggtttctg ccatcaagcc tcctcgtgaa 750

 gagttcctca acagccggat gctgatgccc caagacatca tggcctatcg 800

 gggtcgtgag gtggtggaga acaacctgcc actgaggagc gcccctgggt 850

 gtgagagcag agcctttgcc cccagcctgt acagtggcct gtccacaccg 900

 ccagcctctt attccatgta cagccacctc cctgtcagca gcctcctctt 950

 ctccgatgag gagtttcggg atgtccggat gcctgtggcc aaccccttcc 1000

 ccaaggagcg ggcactccca tgtgatagtg ccaggccagt ccctggtgag 1050

 tacagccggc cgactttgga ggtgtccccc aatgtgtgcc acagcaatat 1100

 ctattcaccc aaggaaacaa tcccagaaga ggcacgaagt gatatgcact 1150

 acagtgtggc tgagggcctc aaacctgctg ccccctcagc ccgaaatgcc 1200

 ccctacttcc cttgtgacaa ggccagcaaa gaagaagaga gaccctcctc 1250

 ggaagatgag attgccctgc atttcgagcc ccccaatgca cccctgaacc 1300

 ggaagggtct ggttagtcca cagagccccc agaaatctga ctgccagccc 1350

 aactcgccca cagaggcctg cagcagtaag aatgcctgca tcctccaggc 1400

 ttctggctcc cctccagcca agagccccac tgaccccaaa gcctgcaact 1450

 ggaagaaata caagttcatc gtgctcaaca gcctcaacca gaatgccaaa 1500

 ccaggggggc ctgagcaggc tgagctgggc cgcctttccc cacgagccta 1550

 cacggcccca cctgcctgcc agccacccat ggagcctgag aaccttgacc 1600

 tccagtcccc aaccaagctg agtgccagcg gggaggactc caccatccca 1650

 caagccagcc ggctcaataa catcgttaac aggtccatga cgggctctcc 1700

 ccgcagcagc agcgagagcc actcaccact ctacatgcac cccccgaagt 1750

 gcacgtcctg cggctctcag tccccacagc atgcagagat gtgcctccac 1800

 accgctggcc ccacgttcgc tgaggagatg ggagagaccc agtctgagta 1850

 ctcagattct agctgtgaga acggggcctt cttctgcaat gagtgtgact 1900

 gccgcttctc tgaggaggcc tcactcaaga ggcacacgct gcagacccac 1950

 agtgacaaac cctacaagtg tgaccgctgc caggcctcct tccgctacaa 2000

 gggcaacctc gccagccaca agaccgtcca taccggtgag aaaccctatc 2050

 gttgcaacat ctgtggggcc cagttcaacc ggccagccaa cctgaaaacc 2100

 cacactcgaa ttcactctgg agagaagccc tacaaatgcg aaacctgcgg 2150

 agccagattt gtacaggtgg cccacctccg tgcccatgtg cttatccaca 2200

 ctggtgagaa gccctatccc tgtgaaatct gtggcacccg tttccggcac 2250

 cttcagactc tgaagagcca cctgcgaatc cacacaggag agaaacctta 2300

 ccattgtgag aagtgtaacc tgcatttccg tcacaaaagc cagctgcgac 2350

 ttcacttgcg ccagaagcat ggcgccatca ccaacaccaa ggtgcaatac 2400

 cgcgtgtcag ccactgacct gcctccggag ctccccaaag cctgctgaag 2450

 catggagtgt tgatgctttc gtctccagcc ccttctcaga atctacccaa 2500

 aggatactgt aacactttac aatgttcatc ccatgatgta gtgcctcttt 2550

 catccactag tgcaaatcat agctgggggt tgggggtggt gggggtcggg 2600

 gcctggggga ctgggagccg cagcagctcc ccctccccca ctgccataaa 2650

 acattaagaa aatcatattg cttcttctcc tatgtgtaag gtgaaccatg 2700

 tcagcaaaaa gcaaaatcat tttatatgtc aaagcagggg agtatgcaaa 2750

 agttctgact tgactttagt ctgcaaaatg aggaatgtat atgttttgtg 2800

 ggaacagatg tttcttttgt atgtaaatgt gcattctttt aaaagacaag 2850

 acttcagtat gttgtcaaag agagggcttt aattttttta accaaaggtg 2900

 aaggaatata tggcagagtt gtaaatatat aaatatatat atatataaaa 2950

 taaatatata taaacctaac aaagatatat taaaaatata aaactgcgtt 3000

 aaaggctcga ttttgtatct gcaggcagac acggatctga gaatctttat 3050

 tgagaaagag cacttaagag aatattttaa gtattgcatc tgtataagta 3100

 agaaaatatt ttgtctaaaa tgcctcagtg tatttgtatt tttttgcaag 3150

 tgaaggttta caatttacaa agtgtgtatt aaaaaaaacc caaagaaccc 3200

 aaaaatctgc agaaggaaaa atgtgtaatt ttgttctagt tttcagtttg 3250

 tatatacccg tacaacgtgt cctcacggtg ccttttttca cggaagtttt 3300

 caatgatggg cgagcgtgca ccatcccttt ttgaagtgta ggcagacaca 3350

 gggacttgaa gttgttacta actaaactct ctttgggaat gtttgtctca 3400

 tcccattctg cgtcatgctt gtgtgataac tactccggag acagggtttg 3450

 gctgtgtcta aactgcatta ccgcgttgta aaaaatagct gtaccaatat 3500

 aagaataaaa tgttggaaag tcgcaaaaaa aaaaaa 3536

<210> 5396
<211> 706
<212> PRT
<213> Mus musculus

<400> 5396
 Met Ala Ser Pro Ala Asp Ser Cys Ile Gln Phe Thr Arg His Ala
   1               5                  10                  15

 Ser Asp Val Leu Leu Asn Leu Asn Arg Leu Arg Ser Arg Asp Ile
                  20                  25                  30

 Leu Thr Asp Val Val Ile Val Val Ser Arg Glu Gln Phe Arg Ala
                  35                  40                  45

 His Lys Thr Val Leu Met Ala Cys Ser Gly Leu Phe Tyr Ser Ile
                  50                  55                  60

 Phe Thr Asp Gln Leu Lys Cys Asn Leu Ser Val Ile Asn Leu Asp
                  65                  70                  75

 Pro Glu Ile Asn Pro Glu Gly Phe Cys Ile Leu Leu Asp Phe Met
                  80                  85                  90

 Tyr Thr Ser Arg Leu Asn Leu Arg Glu Gly Asn Ile Met Ala Val
                  95                 100                 105

 Met Ala Thr Ala Met Tyr Leu Gln Met Glu His Val Val Asp Thr
                 110                 115                 120

 Cys Arg Lys Phe Ile Lys Ala Ser Glu Ala Glu Met Val Ser Ala
                 125                 130                 135

 Ile Lys Pro Pro Arg Glu Glu Phe Leu Asn Ser Arg Met Leu Met
                 140                 145                 150

 Pro Gln Asp Ile Met Ala Tyr Arg Gly Arg Glu Val Val Glu Asn
                 155                 160                 165

 Asn Leu Pro Leu Arg Ser Ala Pro Gly Cys Glu Ser Arg Ala Phe
                 170                 175                 180

 Ala Pro Ser Leu Tyr Ser Gly Leu Ser Thr Pro Pro Ala Ser Tyr
                 185                 190                 195

 Ser Met Tyr Ser His Leu Pro Val Ser Ser Leu Leu Phe Ser Asp
                 200                 205                 210

 Glu Glu Phe Arg Asp Val Arg Met Pro Val Ala Asn Pro Phe Pro
                 215                 220                 225

 Lys Glu Arg Ala Leu Pro Cys Asp Ser Ala Arg Pro Val Pro Gly
                 230                 235                 240

 Glu Tyr Ser Arg Pro Thr Leu Glu Val Ser Pro Asn Val Cys His
                 245                 250                 255

 Ser Asn Ile Tyr Ser Pro Lys Glu Thr Ile Pro Glu Glu Ala Arg
                 260                 265                 270

 Ser Asp Met His Tyr Ser Val Ala Glu Gly Leu Lys Pro Ala Ala
                 275                 280                 285

 Pro Ser Ala Arg Asn Ala Pro Tyr Phe Pro Cys Asp Lys Ala Ser
                 290                 295                 300

 Lys Glu Glu Glu Arg Pro Ser Ser Glu Asp Glu Ile Ala Leu His
                 305                 310                 315

 Phe Glu Pro Pro Asn Ala Pro Leu Asn Arg Lys Gly Leu Val Ser
                 320                 325                 330

 Pro Gln Ser Pro Gln Lys Ser Asp Cys Gln Pro Asn Ser Pro Thr
                 335                 340                 345

 Glu Ala Cys Ser Ser Lys Asn Ala Cys Ile Leu Gln Ala Ser Gly
                 350                 355                 360

 Ser Pro Pro Ala Lys Ser Pro Thr Asp Pro Lys Ala Cys Asn Trp
                 365                 370                 375

 Lys Lys Tyr Lys Phe Ile Val Leu Asn Ser Leu Asn Gln Asn Ala
                 380                 385                 390

 Lys Pro Gly Gly Pro Glu Gln Ala Glu Leu Gly Arg Leu Ser Pro
                 395                 400                 405

 Arg Ala Tyr Thr Ala Pro Pro Ala Cys Gln Pro Pro Met Glu Pro
                 410                 415                 420

 Glu Asn Leu Asp Leu Gln Ser Pro Thr Lys Leu Ser Ala Ser Gly
                 425                 430                 435

 Glu Asp Ser Thr Ile Pro Gln Ala Ser Arg Leu Asn Asn Ile Val
                 440                 445                 450

 Asn Arg Ser Met Thr Gly Ser Pro Arg Ser Ser Ser Glu Ser His
                 455                 460                 465

 Ser Pro Leu Tyr Met His Pro Pro Lys Cys Thr Ser Cys Gly Ser
                 470                 475                 480

 Gln Ser Pro Gln His Ala Glu Met Cys Leu His Thr Ala Gly Pro
                 485                 490                 495

 Thr Phe Ala Glu Glu Met Gly Glu Thr Gln Ser Glu Tyr Ser Asp
                 500                 505                 510

 Ser Ser Cys Glu Asn Gly Ala Phe Phe Cys Asn Glu Cys Asp Cys
                 515                 520                 525

 Arg Phe Ser Glu Glu Ala Ser Leu Lys Arg His Thr Leu Gln Thr
                 530                 535                 540

 His Ser Asp Lys Pro Tyr Lys Cys Asp Arg Cys Gln Ala Ser Phe
                 545                 550                 555

 Arg Tyr Lys Gly Asn Leu Ala Ser His Lys Thr Val His Thr Gly
                 560                 565                 570

 Glu Lys Pro Tyr Arg Cys Asn Ile Cys Gly Ala Gln Phe Asn Arg
                 575                 580                 585

 Pro Ala Asn Leu Lys Thr His Thr Arg Ile His Ser Gly Glu Lys
                 590                 595                 600

 Pro Tyr Lys Cys Glu Thr Cys Gly Ala Arg Phe Val Gln Val Ala
                 605                 610                 615

 His Leu Arg Ala His Val Leu Ile His Thr Gly Glu Lys Pro Tyr
                 620                 625                 630

 Pro Cys Glu Ile Cys Gly Thr Arg Phe Arg His Leu Gln Thr Leu
                 635                 640                 645

 Lys Ser His Leu Arg Ile His Thr Gly Glu Lys Pro Tyr His Cys
                 650                 655                 660

 Glu Lys Cys Asn Leu His Phe Arg His Lys Ser Gln Leu Arg Leu
                 665                 670                 675

 His Leu Arg Gln Lys His Gly Ala Ile Thr Asn Thr Lys Val Gln
                 680                 685                 690

 Tyr Arg Val Ser Ala Thr Asp Leu Pro Pro Glu Leu Pro Lys Ala
                 695                 700                 705

 Cys


<210> 5397
<211> 4117
<212> DNA
<213> Homo sapien

<400> 5397
 tccgcctctc tctttactgc ggcgcggggc aaggtgtgcg ggcgggaagg 50

 ggcacgggca cccccgcggt ccccgggagg ctagagatca tggaagggaa 100

 gtggttgctg tgtatgttac tggtgcttgg aactgctatt gttgaggctc 150

 atgatggaca tgatgatgat gtgattgata ttgaggatga ccttgacgat 200

 gtcattgaag aggtagaaga ctcaaaacca gataccactg ctcctccttc 250

 atctcccaag gttacttaca aagctccagt tccaacaggg gaagtatatt 300

 ttgctgattc ttttgacaga ggaactctgt cagggtggat tttatccaaa 350

 gccaagaaag acgataccga tgatgaaatt gccaaatatg atggaaagtg 400

 ggaggtagag gaaatgaagg agtcaaagct tccaggtgat aaaggacttg 450

 tgttgatgtc tcgggccaag catcatgcga tctctgctaa actgaacaag 500

 cccttcctgt ttgacaccaa gcctctcatt gttcagtatg aggttaattt 550

 ccaaaatgga atagaatgtg gtggtgccta tgtgaaactg ctttctaaaa 600

 caccagaact caacctggat cagttccatg acaagacccc ttatacgatt 650

 atgtttggtc cagataaatg tggagaggac tataaactgc acttcatctt 700

 ccgacacaaa aaccccaaaa cgggtatcta tgaagaaaaa catgctaaga 750

 ggccagatgc agatctgaag acctatttta ctgataagaa aacacatctt 800

 tacacactaa tcttgaatcc agataatagt tttgaaatac tggttgacca 850

 atctgtggtg aatagtggaa atctgctcaa tgacatgact cctcctgtaa 900

 atccttcacg tgaaattgag gacccagaag accggaagcc cgaggattgg 950

 gatgaaagac caaaaatccc agatccagaa gctgtcaagc cagatgactg 1000

 ggatgaagat gcccctgcta agattccaga tgaagaggcc acaaaacccg 1050

 aaggctggtt agatgatgag cctgagtacg tacctgatcc agacgcagag 1100

 aaacctgagg attgggatga agacatggat ggagaatggg aggctcctca 1150

 gattgccaac cctagatgtg agtcagctcc tggatgtggt gtctggcagc 1200

 gacctgtgat tgacaacccc aattataaag gcaaatggaa gcctcctatg 1250

 attgacaatc ccagttacca gggaatctgg aaacccagga aaataccaaa 1300

 tccagatttc tttgaagatc tggaaccttt cagaatgact ccttttagtg 1350

 ctattggttt ggagctgtgg tccatgacct ctgacatttt ttttgacaac 1400

 tttatcattt gtgctgatcg aagaatagtt gatgattggg ccaatgatgg 1450

 atggggcctg aagaaagctg ctgatggggc tgctgagcca ggcgttgtgg 1500

 ggcagatgat cgaggcagct gaagagcgcc cgtggctgtg ggtagtctat 1550

 attctaactg tagcccttcc tgtgttcctg gttatcctct tctgctgttc 1600

 tggaaagaaa cagaccagtg gtatggagta taagaaaact gatgcacctc 1650

 aaccggatgt gaaggaagag gaagaagaga aggaagagga aaaggacaag 1700

 ggagatgagg aggaggaagg agaagagaaa cttgaagaga aacagaaaag 1750

 tgatgctgaa gaagatggtg gcactgtcag tcaagaggag gaagacagaa 1800

 aacctaaagc agaggaggat gaaattttga acagatcacc aagaaacaga 1850

 aagccacgaa gagagtgaaa caatcttaag agcttgatct gtgatttctt 1900

 ctccctcctc ccctgcaaga gtggtcctag gagaggacct ggcacacctt 1950

 aggttgacat tcagaaaact tcaagacatc accatcagca ggctccagtt 2000

 gaacactagt ctgtgtaact ttaaacatct agcagtaaat acttgcagtt 2050

 gtgatataaa ggaccctgtt tctgtagaaa agaaaacatt taacataatg 2100

 gttgtgaaat gtaacatgaa gcaaactaac tttttttttt ttaacatctt 2150

 tgtttttaaa atagaatgat agaactttgc cagtctttaa gatcttggct 2200

 taatttaatg tattaatctg tttgtgcaaa cataatacca ccatttaaaa 2250

 atgttaggga gatgagttgc agtttttata atagattttt tttaaagttt 2300

 ggtattgtaa aacattcaca cctctgtccc tcaaaattga taattacgtt 2350

 taaagtgcag tcatttgtgg ttagaatctt gttttgtttg cttccattat 2400

 tgagttcctc ctaaggaaat tgaggagagg gactgaatag aagcccaaat 2450

 tcatataaaa gttgcgttta agttgtatta aaaatagata tataagaaaa 2500

 aattctttca cttgatgttt gttagaccag aaagtgtgtg tgttctgtag 2550

 ctcagttccc agacagcttt ttaggtagtg gaggaggtgg cttcatgtgg 2600

 cacttgggca tttatattcc acttgggagg gtcaggcctg tggcttctgg 2650

 agcaggtggc ttgttaagga acgctagcag ggcatggcac gtgagctccg 2700

 gaatagatgt cttcatcact tcttccactg tgtgttgaca ctgttttcct 2750

 tacctatttc ctcagatccc cagctttctc ctcgctatgc attttcttca 2800

 cagtgcagct tgcagtccgt tgctgaaaat gattataagc cctgcataat 2850

 gttaagcttt attgtgatta cgtgtatgtt tcttctttct tttaagcaga 2900

 cccatacctt tccagggtca aagtacagaa tagaatacat tgatacaaag 2950

 tacagaaaaa tactttgatt tttatccatt tcttttactc tgtgtaaaga 3000

 ctttagaagt ctaattcaca ggcaaaccaa tacagaattg actgcagttg 3050

 aacagactag aagtatttgt gggaggagtg acatgaagca tgagttatct 3100

 gatttttttt gtagctgcta tatattttaa gccttcattt gcaattcatg 3150

 taacagttgt gtcataaatt acacaataaa gcagtcctgt tcaaattttt 3200

 ttttaacgtg gcttgtagaa tttttaaaaa agtgatctta ggtttgtttt 3250

 ttcatgcggg atgcagatgg gtgctatcag agcctctccc acaccactat 3300

 agtgtaataa tgttattatt actctacact gaaacgtatt cagagttaga 3350

 tattatttta gcttcagttg ttctttagag gctttcaaat gtaccgatga 3400

 tactgtttct tgcactgaat atataaacac tccacagtgt ttatattggg 3450

 aagatattgg gaaggaaata tatttgtaaa agatgaaggc tgtatctatt 3500

 tttttttctt tttaaactgg ttcacttaaa ttcttttgag gatgggatgt 3550

 atttttcttg ctgttcagtg ctttttcctt ttcatctgtt gttctgtggt 3600

 cacagtgacc ttagctacat agcagacttt cccaaatgta ttgattacaa 3650

 ataaacagtt gttacttagc aagacctgaa aatatgtctg caggtttctc 3700

 cttgaagcaa atgtgtggga tcattgcatt tccagaaatc tgcctccttc 3750

 acccaccgtt gacagtatat gtcatgcctc actttcttgt agctgagctt 3800

 taaatcatta gagcttaaat tgtcagatcg ttcattgcct ttccagggtt 3850

 atttagtaaa gtttgttgaa aacaaaaacg ccttttcttg gttctttttt 3900

 cagttatttt gaaggtccag catcctgatt aaatgtctga cacttaatga 3950

 atgaccagca gcagctttca gctcttaaaa agacacttat attttgattt 4000

 tacatgctgg ttacctgttc cattgttgtc aaatgcccag tgtccatcag 4050

 atgtgttcct ccattttctt atccacaaag tactcctcac ttttcaattt 4100

 gtcatgttac taaaccc 4117

<210> 5398
<211> 592
<212> PRT
<213> Homo sapien

<400> 5398
 Met Glu Gly Lys Trp Leu Leu Cys Met Leu Leu Val Leu Gly Thr
   1               5                  10                  15

 Ala Ile Val Glu Ala His Asp Gly His Asp Asp Asp Val Ile Asp
                  20                  25                  30

 Ile Glu Asp Asp Leu Asp Asp Val Ile Glu Glu Val Glu Asp Ser
                  35                  40                  45

 Lys Pro Asp Thr Thr Ala Pro Pro Ser Ser Pro Lys Val Thr Tyr
                  50                  55                  60

 Lys Ala Pro Val Pro Thr Gly Glu Val Tyr Phe Ala Asp Ser Phe
                  65                  70                  75

 Asp Arg Gly Thr Leu Ser Gly Trp Ile Leu Ser Lys Ala Lys Lys
                  80                  85                  90

 Asp Asp Thr Asp Asp Glu Ile Ala Lys Tyr Asp Gly Lys Trp Glu
                  95                 100                 105

 Val Glu Glu Met Lys Glu Ser Lys Leu Pro Gly Asp Lys Gly Leu
                 110                 115                 120

 Val Leu Met Ser Arg Ala Lys His His Ala Ile Ser Ala Lys Leu
                 125                 130                 135

 Asn Lys Pro Phe Leu Phe Asp Thr Lys Pro Leu Ile Val Gln Tyr
                 140                 145                 150

 Glu Val Asn Phe Gln Asn Gly Ile Glu Cys Gly Gly Ala Tyr Val
                 155                 160                 165

 Lys Leu Leu Ser Lys Thr Pro Glu Leu Asn Leu Asp Gln Phe His
                 170                 175                 180

 Asp Lys Thr Pro Tyr Thr Ile Met Phe Gly Pro Asp Lys Cys Gly
                 185                 190                 195

 Glu Asp Tyr Lys Leu His Phe Ile Phe Arg His Lys Asn Pro Lys
                 200                 205                 210

 Thr Gly Ile Tyr Glu Glu Lys His Ala Lys Arg Pro Asp Ala Asp
                 215                 220                 225

 Leu Lys Thr Tyr Phe Thr Asp Lys Lys Thr His Leu Tyr Thr Leu
                 230                 235                 240

 Ile Leu Asn Pro Asp Asn Ser Phe Glu Ile Leu Val Asp Gln Ser
                 245                 250                 255

 Val Val Asn Ser Gly Asn Leu Leu Asn Asp Met Thr Pro Pro Val
                 260                 265                 270

 Asn Pro Ser Arg Glu Ile Glu Asp Pro Glu Asp Arg Lys Pro Glu
                 275                 280                 285

 Asp Trp Asp Glu Arg Pro Lys Ile Pro Asp Pro Glu Ala Val Lys
                 290                 295                 300

 Pro Asp Asp Trp Asp Glu Asp Ala Pro Ala Lys Ile Pro Asp Glu
                 305                 310                 315

 Glu Ala Thr Lys Pro Glu Gly Trp Leu Asp Asp Glu Pro Glu Tyr
                 320                 325                 330

 Val Pro Asp Pro Asp Ala Glu Lys Pro Glu Asp Trp Asp Glu Asp
                 335                 340                 345

 Met Asp Gly Glu Trp Glu Ala Pro Gln Ile Ala Asn Pro Arg Cys
                 350                 355                 360

 Glu Ser Ala Pro Gly Cys Gly Val Trp Gln Arg Pro Val Ile Asp
                 365                 370                 375

 Asn Pro Asn Tyr Lys Gly Lys Trp Lys Pro Pro Met Ile Asp Asn
                 380                 385                 390

 Pro Ser Tyr Gln Gly Ile Trp Lys Pro Arg Lys Ile Pro Asn Pro
                 395                 400                 405

 Asp Phe Phe Glu Asp Leu Glu Pro Phe Arg Met Thr Pro Phe Ser
                 410                 415                 420

 Ala Ile Gly Leu Glu Leu Trp Ser Met Thr Ser Asp Ile Phe Phe
                 425                 430                 435

 Asp Asn Phe Ile Ile Cys Ala Asp Arg Arg Ile Val Asp Asp Trp
                 440                 445                 450

 Ala Asn Asp Gly Trp Gly Leu Lys Lys Ala Ala Asp Gly Ala Ala
                 455                 460                 465

 Glu Pro Gly Val Val Gly Gln Met Ile Glu Ala Ala Glu Glu Arg
                 470                 475                 480

 Pro Trp Leu Trp Val Val Tyr Ile Leu Thr Val Ala Leu Pro Val
                 485                 490                 495

 Phe Leu Val Ile Leu Phe Cys Cys Ser Gly Lys Lys Gln Thr Ser
                 500                 505                 510

 Gly Met Glu Tyr Lys Lys Thr Asp Ala Pro Gln Pro Asp Val Lys
                 515                 520                 525

 Glu Glu Glu Glu Glu Lys Glu Glu Glu Lys Asp Lys Gly Asp Glu
                 530                 535                 540

 Glu Glu Glu Gly Glu Glu Lys Leu Glu Glu Lys Gln Lys Ser Asp
                 545                 550                 555

 Ala Glu Glu Asp Gly Gly Thr Val Ser Gln Glu Glu Glu Asp Arg
                 560                 565                 570

 Lys Pro Lys Ala Glu Glu Asp Glu Ile Leu Asn Arg Ser Pro Arg
                 575                 580                 585

 Asn Arg Lys Pro Arg Arg Glu
                 590

<210> 5399
<211> 1221
<212> DNA
<213> Homo sapien

<400> 5399
 cgcaggctgg aaggaagacg aacctacgaa gcagagatct gaagacagca 50

 tgtacacagc cattccccag agtggctctc cattcccagg ctcagtgcag 100

 gatccaggcc tgcatgtgtg gcgggtggag aagctgaagc cggtgcctgt 150

 ggcgcaagag aaccagggcg tcttcttctc gggggactcc tacctagtgc 200

 tgcacaatgg cccagaagag gtttcccatc tgcacctgtg gataggccag 250

 cagtcatccc gggatgagca gggggcctgt gccgtgctgg ctgtgcacct 300

 caacacgctg ctgggagagc ggcctgtgca gcaccgcgag gtgcagggca 350

 atgagtctga cctcttcatg agctacttcc cacggggcct caagtaccag 400

 gaaggtggtg tggagtcagc atttcacaag acctccacag gagccccagc 450

 tgccatcaag aaactctacc aggtgaaggg gaagaagaac atccgtgcca 500

 ccgagcgggc actgaactgg gacagcttca acactgggga ctgcttcatc 550

 ctggacctgg gccagaacat cttcgcctgg tgtggtggaa agtccaacat 600

 cctggaacgc aacaaggcga gggacctggc cctggccatc cgggacagtg 650

 agcgacaggg caaggcccag gtggagattg tcactgatgg ggaggagcct 700

 gctgagatga tccaggtcct gggccccaag cctgctctga aggagggcaa 750

 ccctgaggaa gacctcacag ctgacaaggc aaatgcccag gccgcagctc 800

 tgtataaggt ctctgatgcc actggacaga tgaacctgac caaggtggct 850

 gactccagcc cctttgccct tgaactgctg atatctgatg actgctttgt 900

 gctggacaac gggctctgtg gcaagatcta tatctggaag gggcgaaaag 950

 cgaatgagaa ggagcggcag gcagccctgc aggtggccga gggcttcatc 1000

 tcgcgcatgc agtacgcccc gaacactcag gtggagattc tgcctcaggg 1050

 ccgtgagagt cccatcttca agcaattttt caaggactgg aaatgagggt 1100

 gggcgtcttc ctgccccatg ctcccctgcc ccccaccacc tgcctgcttg 1150

 cttctctggc tgcctggtca gtgcagaggt gccccctgca gatgttcaat 1200

 aaaggagaca agtgctttcc c 1221

<210> 5400
<211> 348
<212> PRT
<213> Homo sapien

<400> 5400
 Met Tyr Thr Ala Ile Pro Gln Ser Gly Ser Pro Phe Pro Gly Ser
   1               5                  10                  15

 Val Gln Asp Pro Gly Leu His Val Trp Arg Val Glu Lys Leu Lys
                  20                  25                  30

 Pro Val Pro Val Ala Gln Glu Asn Gln Gly Val Phe Phe Ser Gly
                  35                  40                  45

 Asp Ser Tyr Leu Val Leu His Asn Gly Pro Glu Glu Val Ser His
                  50                  55                  60

 Leu His Leu Trp Ile Gly Gln Gln Ser Ser Arg Asp Glu Gln Gly
                  65                  70                  75

 Ala Cys Ala Val Leu Ala Val His Leu Asn Thr Leu Leu Gly Glu
                  80                  85                  90

 Arg Pro Val Gln His Arg Glu Val Gln Gly Asn Glu Ser Asp Leu
                  95                 100                 105

 Phe Met Ser Tyr Phe Pro Arg Gly Leu Lys Tyr Gln Glu Gly Gly
                 110                 115                 120

 Val Glu Ser Ala Phe His Lys Thr Ser Thr Gly Ala Pro Ala Ala
                 125                 130                 135

 Ile Lys Lys Leu Tyr Gln Val Lys Gly Lys Lys Asn Ile Arg Ala
                 140                 145                 150

 Thr Glu Arg Ala Leu Asn Trp Asp Ser Phe Asn Thr Gly Asp Cys
                 155                 160                 165

 Phe Ile Leu Asp Leu Gly Gln Asn Ile Phe Ala Trp Cys Gly Gly
                 170                 175                 180

 Lys Ser Asn Ile Leu Glu Arg Asn Lys Ala Arg Asp Leu Ala Leu
                 185                 190                 195

 Ala Ile Arg Asp Ser Glu Arg Gln Gly Lys Ala Gln Val Glu Ile
                 200                 205                 210

 Val Thr Asp Gly Glu Glu Pro Ala Glu Met Ile Gln Val Leu Gly
                 215                 220                 225

 Pro Lys Pro Ala Leu Lys Glu Gly Asn Pro Glu Glu Asp Leu Thr
                 230                 235                 240

 Ala Asp Lys Ala Asn Ala Gln Ala Ala Ala Leu Tyr Lys Val Ser
                 245                 250                 255

 Asp Ala Thr Gly Gln Met Asn Leu Thr Lys Val Ala Asp Ser Ser
                 260                 265                 270

 Pro Phe Ala Leu Glu Leu Leu Ile Ser Asp Asp Cys Phe Val Leu
                 275                 280                 285

 Asp Asn Gly Leu Cys Gly Lys Ile Tyr Ile Trp Lys Gly Arg Lys
                 290                 295                 300

 Ala Asn Glu Lys Glu Arg Gln Ala Ala Leu Gln Val Ala Glu Gly
                 305                 310                 315

 Phe Ile Ser Arg Met Gln Tyr Ala Pro Asn Thr Gln Val Glu Ile
                 320                 325                 330

 Leu Pro Gln Gly Arg Glu Ser Pro Ile Phe Lys Gln Phe Phe Lys
                 335                 340                 345

 Asp Trp Lys


<210> 5401
<211> 3419
<212> DNA
<213> Homo sapien

<400> 5401
 ttccctccgg tgaatcatcg ctcgcagcgg cggcgcccgc agtggccgca 50

 gcagcgcgcc gggccctggc cgcgccccag ccgagcgcag cgcggagtcg 100

 ccccgacctt tctctgcgca gtacggccgc cgggaccgca gcatggcggg 150

 catcgcggcc aagctggcga aggaccggga ggcggccgag gggctgggct 200

 cccacgagag ggccatcaag tacctcaacc aggactacga ggcgctgcgg 250

 aacgagtgcc tggaggccgg gacgctcttc caggacccgt ccttcccggc 300

 catcccctcg gccctgggct tcaaggagtt ggggccctac tccagcaaaa 350

 cccggggcat gagatggaag cgccccacgg agatctgcgc tgacccccag 400

 tttatcattg gaggagccac ccgcacagac atctgccaag gagccctagg 450

 tgactgctgg ctgctggcag ccattgcctc cctcaccttg aatgaagaaa 500

 tcctggctcg agtcgtcccc ctaaaccaga gcttccagga aaactatgca 550

 gggatctttc acttccagtt ctggcaatac ggcgagtggg tggaggtggt 600

 ggtggatgac aggctgccca ccaaggacgg ggagctgctc tttgtgcatt 650

 cagccgaagg gagcgagttc tggagcgccc tgctggagaa ggcatacgcc 700

 aagatcaacg gatgctatga agctctatca gggggtgcca ccactgaggg 750

 cttcgaagac ttcaccggag gcattgctga gtggtatgag ttgaagaagc 800

 cccctcccaa cctgttcaag atcatccaga aagctctgca aaaaggctct 850

 ctccttggct gctccatcga catcaccagc gccgcggact cggaggccat 900

 cacgtttcag aagctggtga aggggcacgc gtactcggtc accggagccg 950

 aggaggttga aagtaacgga agcctacaga aactgatccg catccgaaat 1000

 ccctggggag aagtggagtg gacagggcgg tggaatgaca actgcccaag 1050

 ctggaacact atagacccag aggagaggga aaggctgacc agacggcatg 1100

 aagatggaga attctggatg tctttcagtg acttcctgag gcactattcc 1150

 cgcctggaga tctgtaacct gaccccagac actctcacca gcgataccta 1200

 caagaagtgg aaactcacca aaatggatgg gaactggagg cggggctcca 1250

 ccgcgggagg ttgcaggaac tacccgaaca cattctggat gaaccctcag 1300

 tacctgatca agctggagga ggaggatgag gacgaggagg atggggagag 1350

 cggctgcacc ttcctggtgg ggctcattca gaagcaccga cggcggcaga 1400

 ggaagatggg cgaggacatg cacaccatcg gctttggcat ctatgaggtt 1450

 ccagaggagt taagtgggca gaccaacatc cacctcagca aaaacttctt 1500

 cctgacgaat cgcgccaggg agcgctcaga caccttcatc aacctccggg 1550

 aggtgctcaa ccgcttcaag ctgccgccag gagagtacat tctcgtgcct 1600

 tccaccttcg aacccaacaa ggatggggat ttctgcatcc gggtcttttc 1650

 tgaaaagaaa gctgactacc aagctgtcga tgatgaaatc gaggccaatc 1700

 ttgaagagtt cgacatcagc gaggatgaca ttgatgatgg agtcaggaga 1750

 ctgtttgccc agttggcagg agaggatgcg gagatctctg cctttgagct 1800

 gcagaccatc ctgagaaggg ttctagcaaa gcgccaagat atcaagtcag 1850

 atggcttcag catcgagaca tgcaaaatta tggttgacat gctagattcg 1900

 gacgggagtg gcaagctggg gctgaaggag ttctacattc tctggacgaa 1950

 gattcaaaaa taccaaaaaa tttaccgaga aatcgacgtt gacaggtctg 2000

 gtaccatgaa ttcctatgaa atgcggaagg cattagaaga agcaggtttc 2050

 aagatgccct gtcaactcca ccaagtcatc gttgctcggt ttgcagatga 2100

 ccagctcatc atcgattttg ataattttgt tcggtgtttg gttcggctgg 2150

 aaacgctatt caagatattt aagcagctgg atcccgagaa tactggaaca 2200

 atagagctcg accttatctc ttggctctgt ttctcagtac tttgaagtta 2250

 taactaatct gcctgaagac ttctcatgat ggaaaatcag ccaaggacta 2300

 agcttccata gaaatacact ttgtatctgg acctcaaaat tatgggaaca 2350

 tttacttaaa cggatgatca tagctgaaaa taatgatact gtcaatttga 2400

 gatagcagaa gtttcacaca tcaaagtaaa agatttgcat atcattatac 2450

 taaatgcaaa tgagtcgctt aacccttgac aaggtcaaag aaagctttaa 2500

 atctgtaaat agtatacact ttttactttt acacactttc ctgttcatag 2550

 caatattaaa tcaggaaaaa aaaatgcagg gaggtattta acagctgagc 2600

 aaaaacattg agtcgctctc aaaggacacg aggcccttgg cagggaatat 2650

 ttaaagcaac ttcaagttta aaatgcagct gttgattcta ccaaacaaca 2700

 gtccaagatt accatttccc atgagccaac tgggaaacat ggtatatcat 2750

 gaagtaatct tgtcaaggca tctggagagt ccaggagagg agactcacct 2800

 ctgtcgcttg ggttaaacaa gagacaggtt ttgtagaata ttgattggta 2850

 atagtaaatc gttctcctta caatcaagtt cttgacccta ttcggcctta 2900

 tacatctggt cttacaaaga ccaaagggat cctgcgcttg atcaactgaa 2950

 ccagtatgcc aaaaccaggc atccaatttg taaaccaatt atgataaagg 3000

 acaaaataag ctgtttgcca cctcaaaact ttatgaactt caccaccact 3050

 agtgtctgtc catggagtta gaggggacat cacttagaag ttcttataga 3100

 aaggacacaa gtttgtttcc tggctttacc ttgggaaaat gctagcaaca 3150

 ttatagaaat tttgccttgt tgccttatct tcttccaaat gtactgttaa 3200

 ataaaaataa agggttaccc catgcaatca caccatgcca tgttttcctt 3250

 cctggagggc agccccacag gacggtttat gagcacacaa ttatagcttg 3300

 tttctacttt aacagggtat gctgcctctg taaattcatg tattcaaagg 3350

 aaaagacacc ttgcctataa ttaaaatgtg gaactataaa attttttaaa 3400

 atccaaaaaa aaaaaaaaa 3419

<210> 5402
<211> 700
<212> PRT
<213> Homo sapien

<400> 5402
 Met Ala Gly Ile Ala Ala Lys Leu Ala Lys Asp Arg Glu Ala Ala
   1               5                  10                  15

 Glu Gly Leu Gly Ser His Glu Arg Ala Ile Lys Tyr Leu Asn Gln
                  20                  25                  30

 Asp Tyr Glu Ala Leu Arg Asn Glu Cys Leu Glu Ala Gly Thr Leu
                  35                  40                  45

 Phe Gln Asp Pro Ser Phe Pro Ala Ile Pro Ser Ala Leu Gly Phe
                  50                  55                  60

 Lys Glu Leu Gly Pro Tyr Ser Ser Lys Thr Arg Gly Met Arg Trp
                  65                  70                  75

 Lys Arg Pro Thr Glu Ile Cys Ala Asp Pro Gln Phe Ile Ile Gly
                  80                  85                  90

 Gly Ala Thr Arg Thr Asp Ile Cys Gln Gly Ala Leu Gly Asp Cys
                  95                 100                 105

 Trp Leu Leu Ala Ala Ile Ala Ser Leu Thr Leu Asn Glu Glu Ile
                 110                 115                 120

 Leu Ala Arg Val Val Pro Leu Asn Gln Ser Phe Gln Glu Asn Tyr
                 125                 130                 135

 Ala Gly Ile Phe His Phe Gln Phe Trp Gln Tyr Gly Glu Trp Val
                 140                 145                 150

 Glu Val Val Val Asp Asp Arg Leu Pro Thr Lys Asp Gly Glu Leu
                 155                 160                 165

 Leu Phe Val His Ser Ala Glu Gly Ser Glu Phe Trp Ser Ala Leu
                 170                 175                 180

 Leu Glu Lys Ala Tyr Ala Lys Ile Asn Gly Cys Tyr Glu Ala Leu
                 185                 190                 195

 Ser Gly Gly Ala Thr Thr Glu Gly Phe Glu Asp Phe Thr Gly Gly
                 200                 205                 210

 Ile Ala Glu Trp Tyr Glu Leu Lys Lys Pro Pro Pro Asn Leu Phe
                 215                 220                 225

 Lys Ile Ile Gln Lys Ala Leu Gln Lys Gly Ser Leu Leu Gly Cys
                 230                 235                 240

 Ser Ile Asp Ile Thr Ser Ala Ala Asp Ser Glu Ala Ile Thr Phe
                 245                 250                 255

 Gln Lys Leu Val Lys Gly His Ala Tyr Ser Val Thr Gly Ala Glu
                 260                 265                 270

 Glu Val Glu Ser Asn Gly Ser Leu Gln Lys Leu Ile Arg Ile Arg
                 275                 280                 285

 Asn Pro Trp Gly Glu Val Glu Trp Thr Gly Arg Trp Asn Asp Asn
                 290                 295                 300

 Cys Pro Ser Trp Asn Thr Ile Asp Pro Glu Glu Arg Glu Arg Leu
                 305                 310                 315

 Thr Arg Arg His Glu Asp Gly Glu Phe Trp Met Ser Phe Ser Asp
                 320                 325                 330

 Phe Leu Arg His Tyr Ser Arg Leu Glu Ile Cys Asn Leu Thr Pro
                 335                 340                 345

 Asp Thr Leu Thr Ser Asp Thr Tyr Lys Lys Trp Lys Leu Thr Lys
                 350                 355                 360

 Met Asp Gly Asn Trp Arg Arg Gly Ser Thr Ala Gly Gly Cys Arg
                 365                 370                 375

 Asn Tyr Pro Asn Thr Phe Trp Met Asn Pro Gln Tyr Leu Ile Lys
                 380                 385                 390

 Leu Glu Glu Glu Asp Glu Asp Glu Glu Asp Gly Glu Ser Gly Cys
                 395                 400                 405

 Thr Phe Leu Val Gly Leu Ile Gln Lys His Arg Arg Arg Gln Arg
                 410                 415                 420

 Lys Met Gly Glu Asp Met His Thr Ile Gly Phe Gly Ile Tyr Glu
                 425                 430                 435

 Val Pro Glu Glu Leu Ser Gly Gln Thr Asn Ile His Leu Ser Lys
                 440                 445                 450

 Asn Phe Phe Leu Thr Asn Arg Ala Arg Glu Arg Ser Asp Thr Phe
                 455                 460                 465

 Ile Asn Leu Arg Glu Val Leu Asn Arg Phe Lys Leu Pro Pro Gly
                 470                 475                 480

 Glu Tyr Ile Leu Val Pro Ser Thr Phe Glu Pro Asn Lys Asp Gly
                 485                 490                 495

 Asp Phe Cys Ile Arg Val Phe Ser Glu Lys Lys Ala Asp Tyr Gln
                 500                 505                 510

 Ala Val Asp Asp Glu Ile Glu Ala Asn Leu Glu Glu Phe Asp Ile
                 515                 520                 525

 Ser Glu Asp Asp Ile Asp Asp Gly Val Arg Arg Leu Phe Ala Gln
                 530                 535                 540

 Leu Ala Gly Glu Asp Ala Glu Ile Ser Ala Phe Glu Leu Gln Thr
                 545                 550                 555

 Ile Leu Arg Arg Val Leu Ala Lys Arg Gln Asp Ile Lys Ser Asp
                 560                 565                 570

 Gly Phe Ser Ile Glu Thr Cys Lys Ile Met Val Asp Met Leu Asp
                 575                 580                 585

 Ser Asp Gly Ser Gly Lys Leu Gly Leu Lys Glu Phe Tyr Ile Leu
                 590                 595                 600

 Trp Thr Lys Ile Gln Lys Tyr Gln Lys Ile Tyr Arg Glu Ile Asp
                 605                 610                 615

 Val Asp Arg Ser Gly Thr Met Asn Ser Tyr Glu Met Arg Lys Ala
                 620                 625                 630

 Leu Glu Glu Ala Gly Phe Lys Met Pro Cys Gln Leu His Gln Val
                 635                 640                 645

 Ile Val Ala Arg Phe Ala Asp Asp Gln Leu Ile Ile Asp Phe Asp
                 650                 655                 660

 Asn Phe Val Arg Cys Leu Val Arg Leu Glu Thr Leu Phe Lys Ile
                 665                 670                 675

 Phe Lys Gln Leu Asp Pro Glu Asn Thr Gly Thr Ile Glu Leu Asp
                 680                 685                 690

 Leu Ile Ser Trp Leu Cys Phe Ser Val Leu
                 695                 700

<210> 5403
<211> 1229
<212> DNA
<213> Homo sapien

<400> 5403
 gtttattcat ttatttagca gggagttact gagcacttaa ctatatcctg 50

 caggaggtac tgctctaggt actaaagata taagtaaatt tagtcatggc 100

 ccttgctctc atgtgggtta ttggcctcgt gaaggagaca gaagtaggat 150

 aataattaca attttcagtg atgagaatag ctttaaaagg gaaattaatg 200

 ctgagatgat aaagtcccct taagccaaca aaccctctgt agctatagaa 250

 tgagtgcagg tttctattgg tgtggactca gagcaattta caagagctgt 300

 tcatgcagcc atccatttgt gcaaaatagg gtaagaagat tcaagaggat 350

 atttattact tcctcatacc acatggcttt tgatgattct ggattctaaa 400

 caacccagaa tggtcatttc aggcacaacg atactacatt cgtgtgtgtc 450

 tgcttttaaa cttggctggg ctatcagacc ctattctcgg ctcaggtttt 500

 gagaagccat cagccaatgt gtacgtgcat gctgtagctg cagcctgcat 550

 cccttcgcct gcagcctact ttggggaaat aaagtgcctt actgactgta 600

 gccattacag tatcccaagt cttttgacag gtgcctgtcc ttgaaaaaca 650

 aagtttctat ttttattttt aattggttta gttcttaact gctggccaac 700

 tcttacatcc ccagcaaatc atcgggccat tggatttttt ccattatgtt 750

 catcaccctt atatcatgta cctcagatct ctctctctct cctctctctc 800

 agttatatag tttcttgtct tggacttttt ttttttcttt tctttttctt 850

 ttttttttgc tttaaaacaa gtgtgatgcc atatcaagtc catgttattc 900

 tctcacagtg tactctataa gaggtgtggg tgtctgtttg gtcaggatgt 950

 tagaaagtgc tgataagtag catgatcagt gtatgcgaaa aggtttttag 1000

 gaagtatggc aaaaatgttg tattggctat gatggtgaca tgatatagtc 1050

 agctgccttt taagaggtct tatctgttca gtgttaagtg atttaaaaaa 1100

 ataataacct gttttctgac tagtttaaag atggatttga aaatggtttt 1150

 gaatgcaatt aggttatgct atttggacaa taaactcacc ttgaccttaa 1200

 aaaaaaaaaa aagcggacgc tcgcatcta 1229

<210> 5404
<211> 32
<212> PRT
<213> Homo sapien

<400> 5404
 Met Asp Leu Lys Met Val Leu Asn Ala Ile Arg Leu Cys Tyr Leu
   1               5                  10                  15

 Asp Asn Lys Leu Thr Leu Thr Leu Lys Lys Lys Lys Ser Gly Arg
                  20                  25                  30

 Ser His


<210> 5405
<211> 2010
<212> DNA
<213> Homo sapien

<400> 5405
 cgagaagacc cggatagttc ctcccggcca cgccgcgccg gctctgggca 50

 ctcagcatcg tttccttttc ctccgctgga gcagctatgg cggcggtgaa 100

 gaccctgaac cccaaggccg aggtggcccg agcgcaggcg gcgctggcgg 150

 tcaacatcag cgcagcgcgg ggtctgcagg acgtgctaag gaccaacctg 200

 gggcccaagg gcaccatgaa gatgctcgtt tctggcgctg gagacatcaa 250

 acttactaaa gacggcaatg tgctgcttca cgaaatgcaa attcaacacc 300

 caacagcttc cttaatagca aaggtagcaa cagcccagga tgatataact 350

 ggtgatggta cgacttctaa tgtcctaatc attggagagc tgctgaaaca 400

 ggcggatctc tacatttctg aaggccttca tcctagaata atcactgaag 450

 gatttgaagc tgcaaaggaa aaggcccttc agtttttgga agaagtcaaa 500

 gtaagcagag agatggacag ggaaacactt atagatgtgg ccagaacatc 550

 tcttcgtact aaagttcatg ctgaacttgc agatgtctta acagaggctg 600

 tagtggactc cattttggcc attaaaaagc aagatgaacc tattgatctc 650

 ttcatgattg agatcatgga gatgaaacat aaatctgaaa ctgatacaag 700

 cttaatcaga gggcttgttt tggaccacgg agcacggcat cctgatatga 750

 agaaaagggt ggaggatgca tacatcctca cttgtaacgt gtcattagag 800

 tatgagaaaa cagaagtgaa ttctggcttt ttttacaaga gtgcagaaga 850

 gagagaaaaa ctcgtgaaag ctgaaagaaa attcattgaa gatagggtta 900

 aaaaaataat agaactgaaa aggaaagtct gtggcgattc agataaagga 950

 tttgttgtta ttaatcaaaa gggaattgac cccttttcct tagatgctct 1000

 ttcaaaagaa ggcatagtcg ctctgcgcag agctaaaagg agaaatatgg 1050

 agaggctgac tcttgcttgt ggtggggtag ccctgaattc ttttgacgac 1100

 ctaagtcctg actgcttggg acatgcagga cttgtatatg agtatacatt 1150

 gggagaagag aagtttacct ttattgagaa atgtaacaac cctcgttctg 1200

 tcacattatt gatcaaagga ccaaataagc acacactcac tcagatcaaa 1250

 gatgcagtga gggacggctt gagggctgtc aaaaatgcta ttgatgatgg 1300

 ctgtgtggtt ccaggtgctg gtgccgtgga agtggcaatg gcagaagccc 1350

 tgattaaaca taagcccagt gtaaagggca gggcacagct tggagtccaa 1400

 gcatttgctg atgcattgct cattattccc aaggttcttg ctcagaactc 1450

 tggttttgac cttcaggaaa cattagttaa aattcaagca gaacattcag 1500

 aatcaggtca gcttgtgggt gtggacctga acacaggtga gccaatggtg 1550

 gcagcagaag taggcgtatg ggataactat tgtgtaaaga aacagcttct 1600

 tcactcctgc actgtgattg ccaccaacat tctcttggtt gatgagatca 1650

 tgcgagctgg aatgtcttct ctgaaaggtt gaattgaagc ttcctctgta 1700

 tctgaatctt gaagactgca aagtgatcct gaggattaca gctgtggaat 1750

 ttttgtccaa gcttcaaata attttgaaag aaattttccc atatgaaaaa 1800

 aggagagaac actggcatct gttgaaattt ggaagttctg aaattatagt 1850

 atttttaaaa attgcactga agtgtataca cataaagcag gtcttttatc 1900

 cagtgaacag gatgttttgc tttagcagca gtgacataaa attccatgtt 1950

 agataagcat atgttactta ccttgttatt aaatatttct tgaaaagcag 2000

 gccacgaagg 2010

<210> 5406
<211> 531
<212> PRT
<213> Homo sapien

<400> 5406
 Met Ala Ala Val Lys Thr Leu Asn Pro Lys Ala Glu Val Ala Arg
   1               5                  10                  15

 Ala Gln Ala Ala Leu Ala Val Asn Ile Ser Ala Ala Arg Gly Leu
                  20                  25                  30

 Gln Asp Val Leu Arg Thr Asn Leu Gly Pro Lys Gly Thr Met Lys
                  35                  40                  45

 Met Leu Val Ser Gly Ala Gly Asp Ile Lys Leu Thr Lys Asp Gly
                  50                  55                  60

 Asn Val Leu Leu His Glu Met Gln Ile Gln His Pro Thr Ala Ser
                  65                  70                  75

 Leu Ile Ala Lys Val Ala Thr Ala Gln Asp Asp Ile Thr Gly Asp
                  80                  85                  90

 Gly Thr Thr Ser Asn Val Leu Ile Ile Gly Glu Leu Leu Lys Gln
                  95                 100                 105

 Ala Asp Leu Tyr Ile Ser Glu Gly Leu His Pro Arg Ile Ile Thr
                 110                 115                 120

 Glu Gly Phe Glu Ala Ala Lys Glu Lys Ala Leu Gln Phe Leu Glu
                 125                 130                 135

 Glu Val Lys Val Ser Arg Glu Met Asp Arg Glu Thr Leu Ile Asp
                 140                 145                 150

 Val Ala Arg Thr Ser Leu Arg Thr Lys Val His Ala Glu Leu Ala
                 155                 160                 165

 Asp Val Leu Thr Glu Ala Val Val Asp Ser Ile Leu Ala Ile Lys
                 170                 175                 180

 Lys Gln Asp Glu Pro Ile Asp Leu Phe Met Ile Glu Ile Met Glu
                 185                 190                 195

 Met Lys His Lys Ser Glu Thr Asp Thr Ser Leu Ile Arg Gly Leu
                 200                 205                 210

 Val Leu Asp His Gly Ala Arg His Pro Asp Met Lys Lys Arg Val
                 215                 220                 225

 Glu Asp Ala Tyr Ile Leu Thr Cys Asn Val Ser Leu Glu Tyr Glu
                 230                 235                 240

 Lys Thr Glu Val Asn Ser Gly Phe Phe Tyr Lys Ser Ala Glu Glu
                 245                 250                 255

 Arg Glu Lys Leu Val Lys Ala Glu Arg Lys Phe Ile Glu Asp Arg
                 260                 265                 270

 Val Lys Lys Ile Ile Glu Leu Lys Arg Lys Val Cys Gly Asp Ser
                 275                 280                 285

 Asp Lys Gly Phe Val Val Ile Asn Gln Lys Gly Ile Asp Pro Phe
                 290                 295                 300

 Ser Leu Asp Ala Leu Ser Lys Glu Gly Ile Val Ala Leu Arg Arg
                 305                 310                 315

 Ala Lys Arg Arg Asn Met Glu Arg Leu Thr Leu Ala Cys Gly Gly
                 320                 325                 330

 Val Ala Leu Asn Ser Phe Asp Asp Leu Ser Pro Asp Cys Leu Gly
                 335                 340                 345

 His Ala Gly Leu Val Tyr Glu Tyr Thr Leu Gly Glu Glu Lys Phe
                 350                 355                 360

 Thr Phe Ile Glu Lys Cys Asn Asn Pro Arg Ser Val Thr Leu Leu
                 365                 370                 375

 Ile Lys Gly Pro Asn Lys His Thr Leu Thr Gln Ile Lys Asp Ala
                 380                 385                 390

 Val Arg Asp Gly Leu Arg Ala Val Lys Asn Ala Ile Asp Asp Gly
                 395                 400                 405

 Cys Val Val Pro Gly Ala Gly Ala Val Glu Val Ala Met Ala Glu
                 410                 415                 420

 Ala Leu Ile Lys His Lys Pro Ser Val Lys Gly Arg Ala Gln Leu
                 425                 430                 435

 Gly Val Gln Ala Phe Ala Asp Ala Leu Leu Ile Ile Pro Lys Val
                 440                 445                 450

 Leu Ala Gln Asn Ser Gly Phe Asp Leu Gln Glu Thr Leu Val Lys
                 455                 460                 465

 Ile Gln Ala Glu His Ser Glu Ser Gly Gln Leu Val Gly Val Asp
                 470                 475                 480

 Leu Asn Thr Gly Glu Pro Met Val Ala Ala Glu Val Gly Val Trp
                 485                 490                 495

 Asp Asn Tyr Cys Val Lys Lys Gln Leu Leu His Ser Cys Thr Val
                 500                 505                 510

 Ile Ala Thr Asn Ile Leu Leu Val Asp Glu Ile Met Arg Ala Gly
                 515                 520                 525

 Met Ser Ser Leu Lys Gly
                 530

<210> 5407
<211> 1504
<212> DNA
<213> Homo sapien

<400> 5407
 cctaagatga gctttccatg taaatttgta gccagcttcc ttctgatttt 50

 caatgtttct tccaaaggtg cagtctccaa agagattacg aatgccttgg 100

 aaacctgggg tgccttgggt caggacatca acttggacat tcctagtttt 150

 caaatgagtg atgatattga cgatataaaa tgggaaaaaa cttcagacaa 200

 gaaaaagatt gcacaattca gaaaagagaa agagactttc aaggaaaaag 250

 atacatataa gctatttaaa aatggaactc tgaaaattaa gcatctgaag 300

 accgatgatc aggatatcta caaggtatca atatatgata caaaaggaaa 350

 aaatgtgttg gaaaaaatat ttgatttgaa gattcaagag agggtctcaa 400

 aaccaaagat ctcctggact tgtatcaaca caaccctgac ctgtgaggta 450

 atgaatggaa ctgaccccga attaaacctg tatcaagatg ggaaacatct 500

 aaaactttct cagagggtca tcacacacaa gtggaccacc agcctgagtg 550

 caaaattcaa gtgcacagca gggaacaaag tcagcaagga atccagtgtc 600

 gagcctgtca gctgtccaga gaaaggtctg gacatctatc tcatcattgg 650

 catatgtgga ggaggcagcc tcttgatggt ctttgtggca ctgctcgttt 700

 tctatatcac caaaaggaaa aaacagagga gtcggagaaa tgatgaggag 750

 ctggagacaa gagcccacag agtagctact gaagaaaggg gccggaagcc 800

 ccaacaaatt ccagcttcaa cccctcagaa tccagcaact tcccaacatc 850

 ctcctccacc acctggtcat cgttcccagg cacctagtca tcgtcccccg 900

 cctcctggac accgtgttca gcaccagcct cagaagaggc ctcctgctcc 950

 gtcgggcaca caagttcacc agcagaaagg cccgcccctc cccagacctc 1000

 gagttcagcc aaaacctccc catggggcag cagaaaactc attgtcccct 1050

 tcctctaatt aaaaaagata gaaactgtct ttttcaataa aaagcactgt 1100

 ggatttctgc cctcctgatg tgcatatccg tacttccatg aggtgttttc 1150

 tgtgtgcaga acattgtcac ctcctgaggc tgtgggccac agccacctct 1200

 gcatcttcga actcagccat gtggtcaaca tctggagttt ttggtctcct 1250

 cagagagctc catcacacca gtaaggagaa gcaatataag tgtgattgca 1300

 agaatggtag aggaccgagc acagaaatct tagagatttc ttgtcccctc 1350

 tcaggtcatg tgtagatgcg ataaatcaag tgattggtgt gcctgggtct 1400

 cactacaagc agcctatctg cttaagagac tctggagttt cttatgtgcc 1450

 ctggtggaca cttgcccacc atcctgtgag taaaagtgaa ataaaagctt 1500

 tgac 1504

<210> 5408
<211> 351
<212> PRT
<213> Homo sapien

<400> 5408
 Met Ser Phe Pro Cys Lys Phe Val Ala Ser Phe Leu Leu Ile Phe
   1               5                  10                  15

 Asn Val Ser Ser Lys Gly Ala Val Ser Lys Glu Ile Thr Asn Ala
                  20                  25                  30

 Leu Glu Thr Trp Gly Ala Leu Gly Gln Asp Ile Asn Leu Asp Ile
                  35                  40                  45

 Pro Ser Phe Gln Met Ser Asp Asp Ile Asp Asp Ile Lys Trp Glu
                  50                  55                  60

 Lys Thr Ser Asp Lys Lys Lys Ile Ala Gln Phe Arg Lys Glu Lys
                  65                  70                  75

 Glu Thr Phe Lys Glu Lys Asp Thr Tyr Lys Leu Phe Lys Asn Gly
                  80                  85                  90

 Thr Leu Lys Ile Lys His Leu Lys Thr Asp Asp Gln Asp Ile Tyr
                  95                 100                 105

 Lys Val Ser Ile Tyr Asp Thr Lys Gly Lys Asn Val Leu Glu Lys
                 110                 115                 120

 Ile Phe Asp Leu Lys Ile Gln Glu Arg Val Ser Lys Pro Lys Ile
                 125                 130                 135

 Ser Trp Thr Cys Ile Asn Thr Thr Leu Thr Cys Glu Val Met Asn
                 140                 145                 150

 Gly Thr Asp Pro Glu Leu Asn Leu Tyr Gln Asp Gly Lys His Leu
                 155                 160                 165

 Lys Leu Ser Gln Arg Val Ile Thr His Lys Trp Thr Thr Ser Leu
                 170                 175                 180

 Ser Ala Lys Phe Lys Cys Thr Ala Gly Asn Lys Val Ser Lys Glu
                 185                 190                 195

 Ser Ser Val Glu Pro Val Ser Cys Pro Glu Lys Gly Leu Asp Ile
                 200                 205                 210

 Tyr Leu Ile Ile Gly Ile Cys Gly Gly Gly Ser Leu Leu Met Val
                 215                 220                 225

 Phe Val Ala Leu Leu Val Phe Tyr Ile Thr Lys Arg Lys Lys Gln
                 230                 235                 240

 Arg Ser Arg Arg Asn Asp Glu Glu Leu Glu Thr Arg Ala His Arg
                 245                 250                 255

 Val Ala Thr Glu Glu Arg Gly Arg Lys Pro Gln Gln Ile Pro Ala
                 260                 265                 270

 Ser Thr Pro Gln Asn Pro Ala Thr Ser Gln His Pro Pro Pro Pro
                 275                 280                 285

 Pro Gly His Arg Ser Gln Ala Pro Ser His Arg Pro Pro Pro Pro
                 290                 295                 300

 Gly His Arg Val Gln His Gln Pro Gln Lys Arg Pro Pro Ala Pro
                 305                 310                 315

 Ser Gly Thr Gln Val His Gln Gln Lys Gly Pro Pro Leu Pro Arg
                 320                 325                 330

 Pro Arg Val Gln Pro Lys Pro Pro His Gly Ala Ala Glu Asn Ser
                 335                 340                 345

 Leu Ser Pro Ser Ser Asn
                 350

<210> 5409
<211> 1246
<212> DNA
<213> Homo sapien

<400> 5409
 gaccagccta cagccgcctg catctgtatc cagcgccagg tcccgccagt 50

 cccagctgcg cgcgcccccc agtcccgcac ccgttcggcc caggctaagt 100

 tagccctcac catgccggtc aaaggaggca ccaagtgcat caaatacctg 150

 ctgttcggat ttaacttcat cttctggctt gccgggattg ctgtccttgc 200

 cattggacta tggctccgat tcgactctca gaccaagagc atcttcgagc 250

 aagaaactaa taataataat tccagcttct acacaggagt ctatattctg 300

 atcggagccg gcgccctcat gatgctggtg ggcttcctgg gctgctgcgg 350

 ggctgtgcag gagtcccagt gcatgctggg actgttcttc ggcttcctct 400

 tggtgatatt cgccattgaa atagctgcgg ccatctgggg atattcccac 450

 aaggatgagg tgattaagga agtccaggag ttttacaagg acacctacaa 500

 caagctgaaa accaaggatg agccccagcg ggaaacgctg aaagccatcc 550

 actatgcgtt gaactgctgt ggtttggctg ggggcgtgga acagtttatc 600

 tcagacatct gccccaagaa ggacgtactc gaaaccttca ccgtgaagtc 650

 ctgtcctgat gccatcaaag aggtcttcga caataaattc cacatcatcg 700

 gcgcagtggg catcggcatt gccgtggtca tgatatttgg catgatcttc 750

 agtatgatct tgtgctgtgc tatccgcagg aaccgcgaga tggtctagag 800

 tcagcttaca tccctgagca ggaaagttta cccatgaaga ttggtgggat 850

 tttttgtttg tttgttttgt tttgtttgtt gtttgttgtt tgtttttttg 900

 ccactaattt tagtattcat tctgcattgc tagataaaag ctgaagttac 950

 tttatgtttg tcttttaatg cttcattcaa tattgacatt tgtagttgag 1000

 cggggggttt ggtttgcttt ggtttatatt ttttcagttg tttgtttttg 1050

 cttgttatat taagcagaaa tcctgcaatg aaaggtacta tatttgctag 1100

 actctagaca agatattgta cataaaagaa tttttttgtc tttaaataga 1150

 tacaaatgtc tatcaacttt aatcaagttg taacttatat tgaagacaat 1200

 ttgatacata ataaaaaatt atgacaatgt caaaaaaaaa aaaaaa 1246

<210> 5410
<211> 228
<212> PRT
<213> Homo sapien

<400> 5410
 Met Pro Val Lys Gly Gly Thr Lys Cys Ile Lys Tyr Leu Leu Phe
   1               5                  10                  15

 Gly Phe Asn Phe Ile Phe Trp Leu Ala Gly Ile Ala Val Leu Ala
                  20                  25                  30

 Ile Gly Leu Trp Leu Arg Phe Asp Ser Gln Thr Lys Ser Ile Phe
                  35                  40                  45

 Glu Gln Glu Thr Asn Asn Asn Asn Ser Ser Phe Tyr Thr Gly Val
                  50                  55                  60

 Tyr Ile Leu Ile Gly Ala Gly Ala Leu Met Met Leu Val Gly Phe
                  65                  70                  75

 Leu Gly Cys Cys Gly Ala Val Gln Glu Ser Gln Cys Met Leu Gly
                  80                  85                  90

 Leu Phe Phe Gly Phe Leu Leu Val Ile Phe Ala Ile Glu Ile Ala
                  95                 100                 105

 Ala Ala Ile Trp Gly Tyr Ser His Lys Asp Glu Val Ile Lys Glu
                 110                 115                 120

 Val Gln Glu Phe Tyr Lys Asp Thr Tyr Asn Lys Leu Lys Thr Lys
                 125                 130                 135

 Asp Glu Pro Gln Arg Glu Thr Leu Lys Ala Ile His Tyr Ala Leu
                 140                 145                 150

 Asn Cys Cys Gly Leu Ala Gly Gly Val Glu Gln Phe Ile Ser Asp
                 155                 160                 165

 Ile Cys Pro Lys Lys Asp Val Leu Glu Thr Phe Thr Val Lys Ser
                 170                 175                 180

 Cys Pro Asp Ala Ile Lys Glu Val Phe Asp Asn Lys Phe His Ile
                 185                 190                 195

 Ile Gly Ala Val Gly Ile Gly Ile Ala Val Val Met Ile Phe Gly
                 200                 205                 210

 Met Ile Phe Ser Met Ile Leu Cys Cys Ala Ile Arg Arg Asn Arg
                 215                 220                 225

 Glu Met Val


<210> 5411
<211> 1125
<212> DNA
<213> Homo sapien

<400> 5411
 gtctccccca ctgtcagcac ctcttctgtg tggtgagtgg accgcttacc 50

 ccactaggtg aagatgtcag cccaggagag ctgcctcagc ctcatcaagt 100

 acttcctctt cgttttcaac ctcttcttct tcgtcctcgg cagcctgatc 150

 ttctgcttcg gcatctggat cctcatcgac aagaccagct tcgtgtcctt 200

 tgtgggcttg gccttcgtgc ctctgcagat ctggtccaaa gtcctggcca 250

 tctcaggaat cttcaccatg ggcatcgccc tcctgggttg tgtgggggcc 300

 ctcaaggagc tccgctgcct cctgggcctg tattttggga tgctgctgct 350

 cctgtttgcc acacagatca ccctgggaat cctcatctcc actcagcggg 400

 cccagctgga gcgaagcttg cgggacgtcg tagagaaaac catccaaaag 450

 tacggcacca accccgagga gaccgcggcc gaggagagct gggactatgt 500

 gcagttccag ctgcgctgct gcggctggca ctacccgcag gactggttcc 550

 aagtcctcat cctgagaggt aacgggtcgg aggcgcaccg cgtgccctgc 600

 tcctgctaca acttgtcggc gaccaacgac tccacaatcc tagataaggt 650

 gatcttgccc cagctcagca ggcttggaca cctggcgcgg tccagacaca 700

 gtgcagacat ctgcgctgtc cctgcagaga gccacatcta ccgcgagggc 750

 tgcgcgcagg gcctccagaa gtggctgcac aacaacctta tttccatagt 800

 gggcatttgc ctgggcgtcg gcctactcga gctcgggttc atgacgctct 850

 cgatattcct gtgcagaaac ctggaccacg tctacaaccg gctcgctcga 900

 taccgttagg ccccgccctc cccaaagtcc cgccccgccc ccgtcacgtg 950

 cgctgggcac ttccctgctg cctgtaaata tttgtttaat ccccagttcg 1000

 cctggagccc tccgccttca cattcccctg gggacccacg tggctgcgtg 1050

 cccctgctgc tgtcacctct cccacgggac ctggggcttt cgtccacagc 1100

 ttcctgtccc catctgtcgg cctac 1125

<210> 5412
<211> 281
<212> PRT
<213> Homo sapien

<400> 5412
 Met Ser Ala Gln Glu Ser Cys Leu Ser Leu Ile Lys Tyr Phe Leu
   1               5                  10                  15

 Phe Val Phe Asn Leu Phe Phe Phe Val Leu Gly Ser Leu Ile Phe
                  20                  25                  30

 Cys Phe Gly Ile Trp Ile Leu Ile Asp Lys Thr Ser Phe Val Ser
                  35                  40                  45

 Phe Val Gly Leu Ala Phe Val Pro Leu Gln Ile Trp Ser Lys Val
                  50                  55                  60

 Leu Ala Ile Ser Gly Ile Phe Thr Met Gly Ile Ala Leu Leu Gly
                  65                  70                  75

 Cys Val Gly Ala Leu Lys Glu Leu Arg Cys Leu Leu Gly Leu Tyr
                  80                  85                  90

 Phe Gly Met Leu Leu Leu Leu Phe Ala Thr Gln Ile Thr Leu Gly
                  95                 100                 105

 Ile Leu Ile Ser Thr Gln Arg Ala Gln Leu Glu Arg Ser Leu Arg
                 110                 115                 120

 Asp Val Val Glu Lys Thr Ile Gln Lys Tyr Gly Thr Asn Pro Glu
                 125                 130                 135

 Glu Thr Ala Ala Glu Glu Ser Trp Asp Tyr Val Gln Phe Gln Leu
                 140                 145                 150

 Arg Cys Cys Gly Trp His Tyr Pro Gln Asp Trp Phe Gln Val Leu
                 155                 160                 165

 Ile Leu Arg Gly Asn Gly Ser Glu Ala His Arg Val Pro Cys Ser
                 170                 175                 180

 Cys Tyr Asn Leu Ser Ala Thr Asn Asp Ser Thr Ile Leu Asp Lys
                 185                 190                 195

 Val Ile Leu Pro Gln Leu Ser Arg Leu Gly His Leu Ala Arg Ser
                 200                 205                 210

 Arg His Ser Ala Asp Ile Cys Ala Val Pro Ala Glu Ser His Ile
                 215                 220                 225

 Tyr Arg Glu Gly Cys Ala Gln Gly Leu Gln Lys Trp Leu His Asn
                 230                 235                 240

 Asn Leu Ile Ser Ile Val Gly Ile Cys Leu Gly Val Gly Leu Leu
                 245                 250                 255

 Glu Leu Gly Phe Met Thr Leu Ser Ile Phe Leu Cys Arg Asn Leu
                 260                 265                 270

 Asp His Val Tyr Asn Arg Leu Ala Arg Tyr Arg
                 275                 280

<210> 5413
<211> 1233
<212> DNA
<213> Homo sapien

<400> 5413
 ctaaagctct cttgctgcct agcctcctgc cggcctcatc ttcgcccagc 50

 caaccccgcc tggagcccta tggccaactg cgagttcagc ccggtgtccg 100

 gggacaaacc ctgctgccgg ctctctagga gagcccaact ctgtcttggc 150

 gtcagtatcc tggtcctgat cctcgtcgtg gtgctcgcgg tggtcgtccc 200

 gaggtggcgc cagacgtgga gcggtccggg caccaccaag cgctttcccg 250

 agaccgtcct ggcgcgatgc gtcaagtaca ctgaaattca tcctgagatg 300

 agacatgtag actgccaaag tgtatgggat gctttcaagg gtgcatttat 350

 ttcaaaacat ccttgcaaca ttactgaaga agactatcag ccactaatga 400

 agttgggaac tcagaccgta ccttgcaaca agattcttct ttggagcaga 450

 ataaaagatc tggcccatca gttcacacag gtccagcggg acatgttcac 500

 cctggaggac acgctgctag gctaccttgc tgatgacctc acatggtgtg 550

 gtgaattcaa cacttccaaa ataaactatc aatcttgccc agactggaga 600

 aaggactgca gcaacaaccc tgtttcagta ttctggaaaa cggtttcccg 650

 caggtttgca gaagctgcct gtgatgtggt ccatgtgatg ctcaatggat 700

 cccgcagtaa aatctttgac aaaaacagca cttttgggag tgtggaagtc 750

 cataatttgc aaccagagaa ggttcagaca ctagaggcct gggtgataca 800

 tggtggaaga gaagattcca gagacttatg ccaggatccc accataaaag 850

 agctggaatc gattataagc aaaaggaata ttcaattttc ctgcaagaat 900

 atctacagac ctgacaagtt tcttcagtgt gtgaaaaatc ctgaggattc 950

 atcttgcaca tctgagatct gagccagtcg ctgtggttgt tttagctcct 1000

 tgactccttg tggtttatgt catcatacat gactcagcat acctgctggt 1050

 gcagagctga agattttgga gggtcctcca caataaggtc aatgccagag 1100

 acggaagcct ttttccccaa agtcttaaaa taacttatat catcagcata 1150

 cctttattgt gatctatcaa tagtcaagaa aaattattgt ataagattag 1200

 aatgaaaatt gtatgttaag ttacttcctt tag 1233

<210> 5414
<211> 300
<212> PRT
<213> Homo sapien

<400> 5414
 Met Ala Asn Cys Glu Phe Ser Pro Val Ser Gly Asp Lys Pro Cys
   1               5                  10                  15

 Cys Arg Leu Ser Arg Arg Ala Gln Leu Cys Leu Gly Val Ser Ile
                  20                  25                  30

 Leu Val Leu Ile Leu Val Val Val Leu Ala Val Val Val Pro Arg
                  35                  40                  45

 Trp Arg Gln Thr Trp Ser Gly Pro Gly Thr Thr Lys Arg Phe Pro
                  50                  55                  60

 Glu Thr Val Leu Ala Arg Cys Val Lys Tyr Thr Glu Ile His Pro
                  65                  70                  75

 Glu Met Arg His Val Asp Cys Gln Ser Val Trp Asp Ala Phe Lys
                  80                  85                  90

 Gly Ala Phe Ile Ser Lys His Pro Cys Asn Ile Thr Glu Glu Asp
                  95                 100                 105

 Tyr Gln Pro Leu Met Lys Leu Gly Thr Gln Thr Val Pro Cys Asn
                 110                 115                 120

 Lys Ile Leu Leu Trp Ser Arg Ile Lys Asp Leu Ala His Gln Phe
                 125                 130                 135

 Thr Gln Val Gln Arg Asp Met Phe Thr Leu Glu Asp Thr Leu Leu
                 140                 145                 150

 Gly Tyr Leu Ala Asp Asp Leu Thr Trp Cys Gly Glu Phe Asn Thr
                 155                 160                 165

 Ser Lys Ile Asn Tyr Gln Ser Cys Pro Asp Trp Arg Lys Asp Cys
                 170                 175                 180

 Ser Asn Asn Pro Val Ser Val Phe Trp Lys Thr Val Ser Arg Arg
                 185                 190                 195

 Phe Ala Glu Ala Ala Cys Asp Val Val His Val Met Leu Asn Gly
                 200                 205                 210

 Ser Arg Ser Lys Ile Phe Asp Lys Asn Ser Thr Phe Gly Ser Val
                 215                 220                 225

 Glu Val His Asn Leu Gln Pro Glu Lys Val Gln Thr Leu Glu Ala
                 230                 235                 240

 Trp Val Ile His Gly Gly Arg Glu Asp Ser Arg Asp Leu Cys Gln
                 245                 250                 255

 Asp Pro Thr Ile Lys Glu Leu Glu Ser Ile Ile Ser Lys Arg Asn
                 260                 265                 270

 Ile Gln Phe Ser Cys Lys Asn Ile Tyr Arg Pro Asp Lys Phe Leu
                 275                 280                 285

 Gln Cys Val Lys Asn Pro Glu Asp Ser Ser Cys Thr Ser Glu Ile
                 290                 295                 300

<210> 5415
<211> 1099
<212> DNA
<213> Homo sapien

<400> 5415
 tcctgcgttg ctgggaagtt ctggaaggaa gcatgtgctc cagaggttgg 50

 gattcgtgtc tggctctgga attgctactg ctgcctctgt cactcctggt 100

 gaccagcatt caaggtcact tggtacatat gaccgtggtc tccggcagca 150

 acgtgactct gaacatctct gagagcctgc ctgagaacta caaacaacta 200

 acctggtttt atactttcga ccagaagatt gtagaatggg attccagaaa 250

 atctaagtac tttgaatcca aatttaaagg cagggtcaga cttgatcctc 300

 agagtggcgc actgtacatc tctaaggtcc agaaagagga caacagcacc 350

 tacatcatga gggtgttgaa aaagactggg aatgagcaag aatggaagat 400

 caagctgcaa gtgcttgacc ctgtacccaa gcctgtcatc aaaattgaga 450

 agatagaaga catggatgac aactgttatt tgaaactgtc atgtgtgata 500

 cctggcgagt ctgtaaacta cacctggtat ggggacaaaa ggcccttccc 550

 aaaggagctc cagaacagtg tgcttgaaac cacccttatg ccacataatt 600

 actccaggtg ttatacttgc caagtcagca attctgtgag cagcaagaat 650

 ggcacggtct gcctcagtcc accctgtacc ctggcccggt cctttggagt 700

 agaatggatt gcaagttggc tagtggtcac ggtgcccacc attcttggcc 750

 tgttacttac ctgagatgag ctcttttaac tcaagcgaaa cttcaaggcc 800

 agaagatctt gcctgttggt gatcatgctc ctcaccagga cagagactgt 850

 ataggctgac cagaagcatg ctgctgaatt atcaacgagg attttcaagt 900

 taacttttaa atactggtta ttatttaatt ttatatccct ttgttgtttt 950

 ctagtacaca gagatataga gatacacatg cttttttccc acccaaaatt 1000

 gtgacaacat tatgtgaatg ttttattatt ttttaaaata aacatttgat 1050

 ataattatca attaactgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1099

<210> 5416
<211> 243
<212> PRT
<213> Homo sapien

<400> 5416
 Met Cys Ser Arg Gly Trp Asp Ser Cys Leu Ala Leu Glu Leu Leu
   1               5                  10                  15

 Leu Leu Pro Leu Ser Leu Leu Val Thr Ser Ile Gln Gly His Leu
                  20                  25                  30

 Val His Met Thr Val Val Ser Gly Ser Asn Val Thr Leu Asn Ile
                  35                  40                  45

 Ser Glu Ser Leu Pro Glu Asn Tyr Lys Gln Leu Thr Trp Phe Tyr
                  50                  55                  60

 Thr Phe Asp Gln Lys Ile Val Glu Trp Asp Ser Arg Lys Ser Lys
                  65                  70                  75

 Tyr Phe Glu Ser Lys Phe Lys Gly Arg Val Arg Leu Asp Pro Gln
                  80                  85                  90

 Ser Gly Ala Leu Tyr Ile Ser Lys Val Gln Lys Glu Asp Asn Ser
                  95                 100                 105

 Thr Tyr Ile Met Arg Val Leu Lys Lys Thr Gly Asn Glu Gln Glu
                 110                 115                 120

 Trp Lys Ile Lys Leu Gln Val Leu Asp Pro Val Pro Lys Pro Val
                 125                 130                 135

 Ile Lys Ile Glu Lys Ile Glu Asp Met Asp Asp Asn Cys Tyr Leu
                 140                 145                 150

 Lys Leu Ser Cys Val Ile Pro Gly Glu Ser Val Asn Tyr Thr Trp
                 155                 160                 165

 Tyr Gly Asp Lys Arg Pro Phe Pro Lys Glu Leu Gln Asn Ser Val
                 170                 175                 180

 Leu Glu Thr Thr Leu Met Pro His Asn Tyr Ser Arg Cys Tyr Thr
                 185                 190                 195

 Cys Gln Val Ser Asn Ser Val Ser Ser Lys Asn Gly Thr Val Cys
                 200                 205                 210

 Leu Ser Pro Pro Cys Thr Leu Ala Arg Ser Phe Gly Val Glu Trp
                 215                 220                 225

 Ile Ala Ser Trp Leu Val Val Thr Val Pro Thr Ile Leu Gly Leu
                 230                 235                 240

 Leu Leu Thr


<210> 5417
<211> 1702
<212> DNA
<213> Homo sapien

<400> 5417
 agactcaaca agagctccag caaagacttt cactgtagct tgacttgacc 50

 tgagattaac tagggaatct tgagaataaa gatgagctct gaaaattgtt 100

 tcgtagcaga gaacagctct ttgcatccgg agagtggaca agaaaatgat 150

 gccaccagtc cccatttctc aacacgtcat gaagggtcct tccaagttcc 200

 tgtcctgtgt gctgtaatga atgtggtctt catcaccatt ttaatcatag 250

 ctctcattgc cttatcagtg ggccaataca attgtccagg ccaatacaca 300

 ttctcaatgc catcagacag ccatgtttct tcatgctctg aggactgggt 350

 tggctaccag aggaaatgct actttatttc tactgtgaag aggagctgga 400

 cttcagccca aaatgcttgt tctgaacatg gtgctactct tgctgtcatt 450

 gattctgaaa aggacatgaa ctttctaaaa cgatacgcag gtagagagga 500

 acactgggtt ggactgaaaa aggaacctgg tcacccatgg aagtggtcaa 550

 atggcaaaga atttaacaac tggttcaacg ttacagggtc tgacaagtgt 600

 gtttttctga aaaacacaga ggtcagcagc atggaatgtg agaagaattt 650

 atactggata tgtaacaaac cttacaaata ataaggaaac atgttcactt 700

 attgactatt atagaatgga actcaaggaa atctgtgtca gtggatgctg 750

 ctctgtggtc cgaagtcttc catagagact ttgtgaaaaa aaattttata 800

 gtgtcttggg aattttcttc caaacagaac tatggaaaaa aaggaagaaa 850

 ttccaggaaa atctgcactg tgggctttta ttgccatgag ctagaagcat 900

 cacaggttga ccaataacca tgcccaagaa tgagaagaat gactatgcaa 950

 cctttggatg cactttatat tattttgaat ccagaaataa tgaaataact 1000

 aggcgtggac ttactattta ttgctgaatg actaccaaca gtgagagccc 1050

 ttcatgcatt tgcactactg gaaggagtta gatgttggta ctagatactg 1100

 aatgtaaaca aaggaattat ggctggtaac ataggttttt agtctaattg 1150

 aatcccttaa actcagggag catttataaa tggacaaatg cttatgaaac 1200

 taagatttgt aatatttctc tctttttaga gaaatttgcc aatttacttt 1250

 gttatttttc cccaaaaaga atgggatgat cgtgtattta tttttttact 1300

 tcctcagctg tagacaggtc cttttcgatg gtacatattt ctttgccttt 1350

 ataatctttt atacagtgtc ttacagagaa aagacataag caaagactat 1400

 gaggaatatt tgcaagacat agaatagtgt tggaaaatgt gcaatatgtg 1450

 atgtggcaaa tctctattag gaaatattct gtaatcttca gacctagaat 1500

 aatactagtc ttataatagg tttgtgactt tcctaaatca attctattac 1550

 gtgcaatact tcaatacttc atttaaaata tttttatgtg caataaaatg 1600

 tatttgtttg tattttgtgt tcagtacaat tataagctgt ttttatatat 1650

 gtgaaataaa agtagaataa acacaaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aa 1702

<210> 5418
<211> 199
<212> PRT
<213> Homo sapien

<400> 5418
 Met Ser Ser Glu Asn Cys Phe Val Ala Glu Asn Ser Ser Leu His
   1               5                  10                  15

 Pro Glu Ser Gly Gln Glu Asn Asp Ala Thr Ser Pro His Phe Ser
                  20                  25                  30

 Thr Arg His Glu Gly Ser Phe Gln Val Pro Val Leu Cys Ala Val
                  35                  40                  45

 Met Asn Val Val Phe Ile Thr Ile Leu Ile Ile Ala Leu Ile Ala
                  50                  55                  60

 Leu Ser Val Gly Gln Tyr Asn Cys Pro Gly Gln Tyr Thr Phe Ser
                  65                  70                  75

 Met Pro Ser Asp Ser His Val Ser Ser Cys Ser Glu Asp Trp Val
                  80                  85                  90

 Gly Tyr Gln Arg Lys Cys Tyr Phe Ile Ser Thr Val Lys Arg Ser
                  95                 100                 105

 Trp Thr Ser Ala Gln Asn Ala Cys Ser Glu His Gly Ala Thr Leu
                 110                 115                 120

 Ala Val Ile Asp Ser Glu Lys Asp Met Asn Phe Leu Lys Arg Tyr
                 125                 130                 135

 Ala Gly Arg Glu Glu His Trp Val Gly Leu Lys Lys Glu Pro Gly
                 140                 145                 150

 His Pro Trp Lys Trp Ser Asn Gly Lys Glu Phe Asn Asn Trp Phe
                 155                 160                 165

 Asn Val Thr Gly Ser Asp Lys Cys Val Phe Leu Lys Asn Thr Glu
                 170                 175                 180

 Val Ser Ser Met Glu Cys Glu Lys Asn Leu Tyr Trp Ile Cys Asn
                 185                 190                 195

 Lys Pro Tyr Lys


<210> 5419
<211> 2419
<212> DNA
<213> Homo sapien

<400> 5419
 cgaaaggccg gccttggctg cgacagcctg ggtaagaggt gtaggtcggc 50

 ttggttttct gctacccgga gctgggcaag cgggttggga gaacagcgaa 100

 gacagcgtga gcctgggccg ttgcctcgag gctctcgccc ggcttctctt 150

 gccgacccgc cacgtttgtt tggatttaat cttacagctg gttgccggcg 200

 cccgcccgcc cgctggcctc gcggtgtgag agggaagcac ccgtgcctgt 250

 ggctggtggc tggcgcctgg agggtccgca cacccgcccg gccgcgccgc 300

 tttgcccgcg gcagccgcgt ccctgaaccg cggagtcgtg tttgtgtttg 350

 acccgcgggc gccggtggcg cgcggccgag gccggtgtcg gcggggcggg 400

 gcggtcgcgg cggaggcaga ggaagaggga gcgggagctc tgcgaggccg 450

 ggcgccgcca tggaactggg cccgagcccc gcaccgcgcc gcctgctctt 500

 cgcctgcagc ccccctcccg cgtcgcagcc cgtcgtgaag gcgctatttg 550

 gcgcttcagc cgccggggga ctgtcgcctg tcaccaacct gaccgtcact 600

 atggaccagc tgcagggtct gggcagtgat tatgagcaac cactggaggt 650

 gaagaacaac agtaatctgc agagaatggg ctcctccgag tcaacagatt 700

 caggtttctg tctagattct cctgggccat tggacagtaa agaaaacctt 750

 gaaaatccta tgagaagaat acattcccta cctcaaaagc tgttgggatg 800

 tagtccagct ctgaagagga gccattctga ttctcttgac catgacatct 850

 ttcagctcat cgacccagat gagaacaagg aaaatgaagc ctttgagttt 900

 aagaagccag taagacctgt atctcgtggc tgcctgcact ctcatggact 950

 ccaggagggt aaagatctct tcacacagag gcagaactct gcccagctcg 1000

 gaatgctttc ctcaaatgaa agagatagca gtgaaccagg gaatttcatt 1050

 cctcttttta caccccagtc acctgtgaca gccactttgt ctgatgagga 1100

 tgatggcttc gtggaccttc tcgatggaga gaatctgaag aatgaggagg 1150

 agaccccctc gtgcatggca agcctctgga cagctcctct cgtcatgaga 1200

 actacaaacc ttgacaaccg atgcaagctg tttgactccc cttccctgtg 1250

 tagctccagc actcggtcag tgttgaagag accagaacgt tctcaagagg 1300

 agtctccacc tggaagtaca aagaggagga agagcatgtc tggggccagc 1350

 cccaaagagt caactaatcc agagaaggcc catgagactc ttcatcagtc 1400

 tttatccctg gcatcttccc ccaaaggaac cattgagaac attttggaca 1450

 atgacccaag ggaccttata ggagacttct ccaagggtta tctctttcat 1500

 acagttgctg ggaaacatca ggatttaaaa tacatctctc cagaaattat 1550

 ggcatctgtt ttgaatggca agtttgccaa cctcattaaa gagtttgtta 1600

 tcatcgactg tcgataccca tatgaatacg agggaggcca catcaagggt 1650

 gcagtgaact tgcacatgga agaagaggtt gaagacttct tattgaagaa 1700

 gcccattgta cctactgatg gcaagcgtgt cattgttgtg tttcactgcg 1750

 agttttcttc tgagagaggt ccccgcatgt gccggtatgt gagagagaga 1800

 gatcgcctgg gtaatgaata ccccaaactc cactaccctg agctgtatgt 1850

 cctgaagggg ggatacaagg agttctttat gaaatgccag tcttactgtg 1900

 agccccctag ctaccggccc atgcaccacg aggactttaa agaagacctg 1950

 aagaagttcc gcaccaagag ccggacctgg gcaggggaga agagcaagag 2000

 ggagatgtac agtcgtctga agaagctctg agggcggcag gaccagccag 2050

 cagcagccca agcttccctc catccccctt taccctcttt cctgcagaga 2100

 aacttaagca aaggggacag ctgtgtgaca tttggagagg gggcctggga 2150

 cttccatgcc ttaaacctac ctcccacact cccaaggttg gagcccaggg 2200

 catcttgctg gctacgcctc ttctgtccct gttagacgtc ctccgtccat 2250

 atcagaactg tgccacaatg cagttctgag caccgtgtca agctgctctg 2300

 agccacagtg ggatgaacca gccggggcct tatcgggctc cagcatctca 2350

 tgaggggaga ggagacggag gggagtagag aagtttacac agaaatgctg 2400

 ctggccaaat agcaaagag 2419

<210> 5420
<211> 523
<212> PRT
<213> Homo sapien

<400> 5420
 Met Glu Leu Gly Pro Ser Pro Ala Pro Arg Arg Leu Leu Phe Ala
   1               5                  10                  15

 Cys Ser Pro Pro Pro Ala Ser Gln Pro Val Val Lys Ala Leu Phe
                  20                  25                  30

 Gly Ala Ser Ala Ala Gly Gly Leu Ser Pro Val Thr Asn Leu Thr
                  35                  40                  45

 Val Thr Met Asp Gln Leu Gln Gly Leu Gly Ser Asp Tyr Glu Gln
                  50                  55                  60

 Pro Leu Glu Val Lys Asn Asn Ser Asn Leu Gln Arg Met Gly Ser
                  65                  70                  75

 Ser Glu Ser Thr Asp Ser Gly Phe Cys Leu Asp Ser Pro Gly Pro
                  80                  85                  90

 Leu Asp Ser Lys Glu Asn Leu Glu Asn Pro Met Arg Arg Ile His
                  95                 100                 105

 Ser Leu Pro Gln Lys Leu Leu Gly Cys Ser Pro Ala Leu Lys Arg
                 110                 115                 120

 Ser His Ser Asp Ser Leu Asp His Asp Ile Phe Gln Leu Ile Asp
                 125                 130                 135

 Pro Asp Glu Asn Lys Glu Asn Glu Ala Phe Glu Phe Lys Lys Pro
                 140                 145                 150

 Val Arg Pro Val Ser Arg Gly Cys Leu His Ser His Gly Leu Gln
                 155                 160                 165

 Glu Gly Lys Asp Leu Phe Thr Gln Arg Gln Asn Ser Ala Gln Leu
                 170                 175                 180

 Gly Met Leu Ser Ser Asn Glu Arg Asp Ser Ser Glu Pro Gly Asn
                 185                 190                 195

 Phe Ile Pro Leu Phe Thr Pro Gln Ser Pro Val Thr Ala Thr Leu
                 200                 205                 210

 Ser Asp Glu Asp Asp Gly Phe Val Asp Leu Leu Asp Gly Glu Asn
                 215                 220                 225

 Leu Lys Asn Glu Glu Glu Thr Pro Ser Cys Met Ala Ser Leu Trp
                 230                 235                 240

 Thr Ala Pro Leu Val Met Arg Thr Thr Asn Leu Asp Asn Arg Cys
                 245                 250                 255

 Lys Leu Phe Asp Ser Pro Ser Leu Cys Ser Ser Ser Thr Arg Ser
                 260                 265                 270

 Val Leu Lys Arg Pro Glu Arg Ser Gln Glu Glu Ser Pro Pro Gly
                 275                 280                 285

 Ser Thr Lys Arg Arg Lys Ser Met Ser Gly Ala Ser Pro Lys Glu
                 290                 295                 300

 Ser Thr Asn Pro Glu Lys Ala His Glu Thr Leu His Gln Ser Leu
                 305                 310                 315

 Ser Leu Ala Ser Ser Pro Lys Gly Thr Ile Glu Asn Ile Leu Asp
                 320                 325                 330

 Asn Asp Pro Arg Asp Leu Ile Gly Asp Phe Ser Lys Gly Tyr Leu
                 335                 340                 345

 Phe His Thr Val Ala Gly Lys His Gln Asp Leu Lys Tyr Ile Ser
                 350                 355                 360

 Pro Glu Ile Met Ala Ser Val Leu Asn Gly Lys Phe Ala Asn Leu
                 365                 370                 375

 Ile Lys Glu Phe Val Ile Ile Asp Cys Arg Tyr Pro Tyr Glu Tyr
                 380                 385                 390

 Glu Gly Gly His Ile Lys Gly Ala Val Asn Leu His Met Glu Glu
                 395                 400                 405

 Glu Val Glu Asp Phe Leu Leu Lys Lys Pro Ile Val Pro Thr Asp
                 410                 415                 420

 Gly Lys Arg Val Ile Val Val Phe His Cys Glu Phe Ser Ser Glu
                 425                 430                 435

 Arg Gly Pro Arg Met Cys Arg Tyr Val Arg Glu Arg Asp Arg Leu
                 440                 445                 450

 Gly Asn Glu Tyr Pro Lys Leu His Tyr Pro Glu Leu Tyr Val Leu
                 455                 460                 465

 Lys Gly Gly Tyr Lys Glu Phe Phe Met Lys Cys Gln Ser Tyr Cys
                 470                 475                 480

 Glu Pro Pro Ser Tyr Arg Pro Met His His Glu Asp Phe Lys Glu
                 485                 490                 495

 Asp Leu Lys Lys Phe Arg Thr Lys Ser Arg Thr Trp Ala Gly Glu
                 500                 505                 510

 Lys Ser Lys Arg Glu Met Tyr Ser Arg Leu Lys Lys Leu
                 515                 520

<210> 5421
<211> 1904
<212> DNA
<213> Homo sapien

<400> 5421
 agctatttca aggcgcgcgc ctcgtggtgg actcaccgct agcccgcagc 50

 gctcggcttc ctggtaattc ttcacctctt ttctcagctc cctgcagcat 100

 gggtgctggg ccctccttgc tgctcgccgc cctcctgctg cttctctccg 150

 gcgacggcgc cgtgcgctgc gacacacctg ccaactgcac ctatcttgac 200

 ctgctgggca cctgggtctt ccaggtgggc tccagcggtt cccagcgcga 250

 tgtcaactgc tcggttatgg gaccacaaga aaaaaaagta gtggtgtacc 300

 ttcagaagct ggatacagca tatgatgacc ttggcaattc tggccatttc 350

 accatcattt acaaccaagg ctttgagatt gtgttgaatg actacaagtg 400

 gtttgccttt tttaagtata aagaagaggg cagcaaggtg accacttact 450

 gcaacgagac aatgactggg tgggtgcatg atgtgttggg ccggaactgg 500

 gcttgtttca ccggaaagaa ggtgggaact gcctctgaga atgtgtatgt 550

 caacacagca caccttaaga attctcagga aaagtattct aataggctct 600

 acaagtatga tcacaacttt gtgaaagcta tcaatgccat tcagaagtct 650

 tggactgcaa ctacatacat ggaatatgag actcttaccc tgggagatat 700

 gattaggaga agtggtggcc acagtcgaaa aatcccaagg cccaaacctg 750

 caccactgac tgctgaaata cagcaaaaga ttttgcattt gccaacatct 800

 tgggactgga gaaatgttca tggtatcaat tttgtcagtc ctgttcgaaa 850

 ccaagcatcc tgtggcagct gctactcatt tgcttctatg ggtatgctag 900

 aagcgagaat ccgtatacta accaacaatt ctcagacccc aatcctaagc 950

 cctcaggagg ttgtgtcttg tagccagtat gctcaaggct gtgaaggcgg 1000

 cttcccatac cttattgcag gaaagtacgc ccaagatttt gggctggtgg 1050

 aagaagcttg cttcccctac acaggcactg attctccatg caaaatgaag 1100

 gaagactgct ttcgttatta ctcctctgag taccactatg taggaggttt 1150

 ctatggaggc tgcaatgaag ccctgatgaa gcttgagttg gtccatcatg 1200

 ggcccatggc agttgctttt gaagtatatg atgacttcct ccactacaaa 1250

 aaggggatct accaccacac tggtctaaga gaccctttca acccctttga 1300

 gctgactaat catgctgttc tgcttgtggg ctatggcact gactcagcct 1350

 ctgggatgga ttactggatt gttaaaaaca gctggggcac cggctggggt 1400

 gagaatggct acttccggat ccgcagagga actgatgagt gtgcaattga 1450

 gagcatagca gtggcagcca caccaattcc taaattgtag ggtatgcctt 1500

 ccagtatttc ataatgatct gcatcagttg taaaggggaa ttggtatatt 1550

 cacagactgt agactttcag cagcaatctc agaagcttac aaatagattt 1600

 ccatgaagat atttgtcttc agaattaaaa ctgcccttaa ttttaatata 1650

 cctttcaatc ggccactggc catttttttc taagtattca attaagtggg 1700

 aattttctgg aagatggtca gctatgaagt aatagagttt gcttaatcat 1750

 ttgtaattca aacatgctat attttttaaa atcaatgtga aaacatagac 1800

 ttatttttaa attgtaccaa tcacaagaaa ataatggcaa taattatcaa 1850

 aacttttaaa atagatgctc atatttttaa aataaagttt taaaaataac 1900

 tgca 1904

<210> 5422
<211> 463
<212> PRT
<213> Homo sapien

<400> 5422
 Met Gly Ala Gly Pro Ser Leu Leu Leu Ala Ala Leu Leu Leu Leu
   1               5                  10                  15

 Leu Ser Gly Asp Gly Ala Val Arg Cys Asp Thr Pro Ala Asn Cys
                  20                  25                  30

 Thr Tyr Leu Asp Leu Leu Gly Thr Trp Val Phe Gln Val Gly Ser
                  35                  40                  45

 Ser Gly Ser Gln Arg Asp Val Asn Cys Ser Val Met Gly Pro Gln
                  50                  55                  60

 Glu Lys Lys Val Val Val Tyr Leu Gln Lys Leu Asp Thr Ala Tyr
                  65                  70                  75

 Asp Asp Leu Gly Asn Ser Gly His Phe Thr Ile Ile Tyr Asn Gln
                  80                  85                  90

 Gly Phe Glu Ile Val Leu Asn Asp Tyr Lys Trp Phe Ala Phe Phe
                  95                 100                 105

 Lys Tyr Lys Glu Glu Gly Ser Lys Val Thr Thr Tyr Cys Asn Glu
                 110                 115                 120

 Thr Met Thr Gly Trp Val His Asp Val Leu Gly Arg Asn Trp Ala
                 125                 130                 135

 Cys Phe Thr Gly Lys Lys Val Gly Thr Ala Ser Glu Asn Val Tyr
                 140                 145                 150

 Val Asn Thr Ala His Leu Lys Asn Ser Gln Glu Lys Tyr Ser Asn
                 155                 160                 165

 Arg Leu Tyr Lys Tyr Asp His Asn Phe Val Lys Ala Ile Asn Ala
                 170                 175                 180

 Ile Gln Lys Ser Trp Thr Ala Thr Thr Tyr Met Glu Tyr Glu Thr
                 185                 190                 195

 Leu Thr Leu Gly Asp Met Ile Arg Arg Ser Gly Gly His Ser Arg
                 200                 205                 210

 Lys Ile Pro Arg Pro Lys Pro Ala Pro Leu Thr Ala Glu Ile Gln
                 215                 220                 225

 Gln Lys Ile Leu His Leu Pro Thr Ser Trp Asp Trp Arg Asn Val
                 230                 235                 240

 His Gly Ile Asn Phe Val Ser Pro Val Arg Asn Gln Ala Ser Cys
                 245                 250                 255

 Gly Ser Cys Tyr Ser Phe Ala Ser Met Gly Met Leu Glu Ala Arg
                 260                 265                 270

 Ile Arg Ile Leu Thr Asn Asn Ser Gln Thr Pro Ile Leu Ser Pro
                 275                 280                 285

 Gln Glu Val Val Ser Cys Ser Gln Tyr Ala Gln Gly Cys Glu Gly
                 290                 295                 300

 Gly Phe Pro Tyr Leu Ile Ala Gly Lys Tyr Ala Gln Asp Phe Gly
                 305                 310                 315

 Leu Val Glu Glu Ala Cys Phe Pro Tyr Thr Gly Thr Asp Ser Pro
                 320                 325                 330

 Cys Lys Met Lys Glu Asp Cys Phe Arg Tyr Tyr Ser Ser Glu Tyr
                 335                 340                 345

 His Tyr Val Gly Gly Phe Tyr Gly Gly Cys Asn Glu Ala Leu Met
                 350                 355                 360

 Lys Leu Glu Leu Val His His Gly Pro Met Ala Val Ala Phe Glu
                 365                 370                 375

 Val Tyr Asp Asp Phe Leu His Tyr Lys Lys Gly Ile Tyr His His
                 380                 385                 390

 Thr Gly Leu Arg Asp Pro Phe Asn Pro Phe Glu Leu Thr Asn His
                 395                 400                 405

 Ala Val Leu Leu Val Gly Tyr Gly Thr Asp Ser Ala Ser Gly Met
                 410                 415                 420

 Asp Tyr Trp Ile Val Lys Asn Ser Trp Gly Thr Gly Trp Gly Glu
                 425                 430                 435

 Asn Gly Tyr Phe Arg Ile Arg Arg Gly Thr Asp Glu Cys Ala Ile
                 440                 445                 450

 Glu Ser Ile Ala Val Ala Ala Thr Pro Ile Pro Lys Leu
                 455                 460

<210> 5423
<211> 1676
<212> DNA
<213> Homo sapien

<400> 5423
 gaattccgcc gctgaccgag gcgtgcaaag actccagaat tggaggcatg 50

 atgaagactc tgctgctgtt tgtggggctg ctgctgacct gggagagtgg 100

 gcaggtcctg ggggaccaga cggtctcaga caatgagctc caggaaatgt 150

 ccaatcaggg aagtaagtac gtcaataagg aaattcaaaa tgctgtcaac 200

 ggggtgaaac agataaagac tctcatagaa aaaacaaacg aagagcgcaa 250

 gacactgctc agcaacctag aagaagccaa gaagaagaaa gaggatgccc 300

 taaatgagac cagggaatca gagacaaagc tgaaggagct cccaggagtg 350

 tgcaatgaga ccatgatggc cctctgggaa gagtgtaagc cctgcctgaa 400

 acagacctgc atgaagttct acgcacgcgt ctgcagaagt ggctcaggcc 450

 tggttggccg ccagcttgag gagttcctga accagagctc gcccttctac 500

 ttctggatga atggtgaccg catcgactcc ctgctggaga acgaccggca 550

 gcagacgcac atgctggatg tcatgcagga ccacttcagc cgcgcgtcca 600

 gcatcataga cgagctcttc caggacaggt tcttcacccg ggagccccag 650

 gatacctacc actacctgcc cttcagcctg ccccaccgga ggcctcactt 700

 cttctttccc aagtcccgca tcgtccgcag cttgatgccc ttctctccgt 750

 acgagcccct gaacttccac gccatgttcc agcccttcct tgagatgata 800

 cacgaggctc agcaggccat ggacatccac ttccacagcc cggccttcca 850

 gcacccgcca acagaattca tacgagaagg cgacgatgac cggactgtgt 900

 gccgggagat ccgccacaac tccacgggct gcctgcggat gaaggaccag 950

 tgtgacaagt gccgggagat cttgtctgtg gactgttcca ccaacaaccc 1000

 ctcccaggct aagctgcggc gggagctcga cgaatccctc caggtcgctg 1050

 agaggttgac caggaaatac aacgagctgc taaagtccta ccagtggaag 1100

 atgctcaaca cctcctcctt gctggagcag ctgaacgagc agtttaactg 1150

 ggtgtcccgg ctggcaaacc tcacgcaagg cgaagaccag tactatctgc 1200

 gggtcaccac ggtggcttcc cacacttctg actcggacgt tccttccggt 1250

 gtcactgagg tggtcgtgaa gctctttgac tctgatccca tcactgtgac 1300

 ggtccctgta gaagtctcca ggaagaaccc taaatttatg gagaccgtgg 1350

 cggagaaagc gctgcaggaa taccgcaaaa agcaccggga ggagtgagat 1400

 gtggatgttg cttttgcacc ttacgggggc atcttgagtc cagctccccc 1450

 caagatgagc tgcagccccc cagagagagc tctgcacgtc accaagtaac 1500

 caggccccag cctccaggcc cccaactccg cccagcctct ccccgctctg 1550

 gatcctgcac tctaacactc gactctgctg ctcatgggaa gaacagaatt 1600

 gctcctgcat gcaactaatt caataaaact gtcttgtgag ctgaaaaaaa 1650

 aaaaaaaaaa aaaaaaaaag gaattc 1676

<210> 5424
<211> 449
<212> PRT
<213> Homo sapien

<400> 5424
 Met Met Lys Thr Leu Leu Leu Phe Val Gly Leu Leu Leu Thr Trp
   1               5                  10                  15

 Glu Ser Gly Gln Val Leu Gly Asp Gln Thr Val Ser Asp Asn Glu
                  20                  25                  30

 Leu Gln Glu Met Ser Asn Gln Gly Ser Lys Tyr Val Asn Lys Glu
                  35                  40                  45

 Ile Gln Asn Ala Val Asn Gly Val Lys Gln Ile Lys Thr Leu Ile
                  50                  55                  60

 Glu Lys Thr Asn Glu Glu Arg Lys Thr Leu Leu Ser Asn Leu Glu
                  65                  70                  75

 Glu Ala Lys Lys Lys Lys Glu Asp Ala Leu Asn Glu Thr Arg Glu
                  80                  85                  90

 Ser Glu Thr Lys Leu Lys Glu Leu Pro Gly Val Cys Asn Glu Thr
                  95                 100                 105

 Met Met Ala Leu Trp Glu Glu Cys Lys Pro Cys Leu Lys Gln Thr
                 110                 115                 120

 Cys Met Lys Phe Tyr Ala Arg Val Cys Arg Ser Gly Ser Gly Leu
                 125                 130                 135

 Val Gly Arg Gln Leu Glu Glu Phe Leu Asn Gln Ser Ser Pro Phe
                 140                 145                 150

 Tyr Phe Trp Met Asn Gly Asp Arg Ile Asp Ser Leu Leu Glu Asn
                 155                 160                 165

 Asp Arg Gln Gln Thr His Met Leu Asp Val Met Gln Asp His Phe
                 170                 175                 180

 Ser Arg Ala Ser Ser Ile Ile Asp Glu Leu Phe Gln Asp Arg Phe
                 185                 190                 195

 Phe Thr Arg Glu Pro Gln Asp Thr Tyr His Tyr Leu Pro Phe Ser
                 200                 205                 210

 Leu Pro His Arg Arg Pro His Phe Phe Phe Pro Lys Ser Arg Ile
                 215                 220                 225

 Val Arg Ser Leu Met Pro Phe Ser Pro Tyr Glu Pro Leu Asn Phe
                 230                 235                 240

 His Ala Met Phe Gln Pro Phe Leu Glu Met Ile His Glu Ala Gln
                 245                 250                 255

 Gln Ala Met Asp Ile His Phe His Ser Pro Ala Phe Gln His Pro
                 260                 265                 270

 Pro Thr Glu Phe Ile Arg Glu Gly Asp Asp Asp Arg Thr Val Cys
                 275                 280                 285

 Arg Glu Ile Arg His Asn Ser Thr Gly Cys Leu Arg Met Lys Asp
                 290                 295                 300

 Gln Cys Asp Lys Cys Arg Glu Ile Leu Ser Val Asp Cys Ser Thr
                 305                 310                 315

 Asn Asn Pro Ser Gln Ala Lys Leu Arg Arg Glu Leu Asp Glu Ser
                 320                 325                 330

 Leu Gln Val Ala Glu Arg Leu Thr Arg Lys Tyr Asn Glu Leu Leu
                 335                 340                 345

 Lys Ser Tyr Gln Trp Lys Met Leu Asn Thr Ser Ser Leu Leu Glu
                 350                 355                 360

 Gln Leu Asn Glu Gln Phe Asn Trp Val Ser Arg Leu Ala Asn Leu
                 365                 370                 375

 Thr Gln Gly Glu Asp Gln Tyr Tyr Leu Arg Val Thr Thr Val Ala
                 380                 385                 390

 Ser His Thr Ser Asp Ser Asp Val Pro Ser Gly Val Thr Glu Val
                 395                 400                 405

 Val Val Lys Leu Phe Asp Ser Asp Pro Ile Thr Val Thr Val Pro
                 410                 415                 420

 Val Glu Val Ser Arg Lys Asn Pro Lys Phe Met Glu Thr Val Ala
                 425                 430                 435

 Glu Lys Ala Leu Gln Glu Tyr Arg Lys Lys His Arg Glu Glu
                 440                 445

<210> 5425
<211> 1201
<212> DNA
<213> Homo sapien

<400> 5425
 tttttcttct tctatcacag ggagaagtga aatgacaacc tcactagata 50

 cagttgagac ctttggtacc acatcctact atgatgacgt gggcctgctc 100

 tgtgaaaaag ctgataccag agcactgatg gcccagtttg tgcccccgct 150

 gtactccctg gtgttcactg tgggcctctt gggcaatgtg gtggtggtga 200

 tgatcctcat aaaatacagg aggctccgaa ttatgaccaa catctacctg 250

 ctcaacctgg ccatttcgga cctgctcttc ctcgtcaccc ttccattctg 300

 gatccactat gtcagggggc ataactgggt ttttggccat ggcatgtgta 350

 agctcctctc agggttttat cacacaggct tgtacagcga gatctttttc 400

 ataatcctgc tgacaatcga caggtacctg gccattgtcc atgctgtgtt 450

 tgcccttcga gcccggactg tcacttttgg tgtcatcacc agcatcgtca 500

 cctggggcct ggcagtgcta gcagctcttc ctgaatttat cttctatgag 550

 actgaagagt tgtttgaaga gactctttgc agtgctcttt acccagagga 600

 tacagtatat agctggaggc atttccacac tctgagaatg accatcttct 650

 gtctcgttct ccctctgctc gttatggcca tctgctacac aggaatcatc 700

 aaaacgctgc tgaggtgccc cagtaaaaaa aagtacaagg ccatccggct 750

 catttttgtc atcatggcgg tgtttttcat tttctggaca ccctacaatg 800

 tggctatcct tctctcttcc tatcaatcca tcttatttgg aaatgactgt 850

 gagcggagca agcatctgga cctggtcatg ctggtgacag aggtgatcgc 900

 ctactcccac tgctgcatga acccggtgat ctacgccttt gttggagaga 950

 ggttccggaa gtacctgcgc cacttcttcc acaggcactt gctcatgcac 1000

 ctgggcagat acatcccatt ccttcctagt gagaagctgg aaagaaccag 1050

 ctctgtctct ccatccacag cagagccgga actctctatt gtgttttagg 1100

 tcagatgcag aaaattgcct aaagaggaag gaccaaggag atgaagcaaa 1150

 cacattaagc cttccacact cacctctaaa acagtccttc aaacttccag 1200

 t 1201

<210> 5426
<211> 355
<212> PRT
<213> Homo sapien

<400> 5426
 Met Thr Thr Ser Leu Asp Thr Val Glu Thr Phe Gly Thr Thr Ser
   1               5                  10                  15

 Tyr Tyr Asp Asp Val Gly Leu Leu Cys Glu Lys Ala Asp Thr Arg
                  20                  25                  30

 Ala Leu Met Ala Gln Phe Val Pro Pro Leu Tyr Ser Leu Val Phe
                  35                  40                  45

 Thr Val Gly Leu Leu Gly Asn Val Val Val Val Met Ile Leu Ile
                  50                  55                  60

 Lys Tyr Arg Arg Leu Arg Ile Met Thr Asn Ile Tyr Leu Leu Asn
                  65                  70                  75

 Leu Ala Ile Ser Asp Leu Leu Phe Leu Val Thr Leu Pro Phe Trp
                  80                  85                  90

 Ile His Tyr Val Arg Gly His Asn Trp Val Phe Gly His Gly Met
                  95                 100                 105

 Cys Lys Leu Leu Ser Gly Phe Tyr His Thr Gly Leu Tyr Ser Glu
                 110                 115                 120

 Ile Phe Phe Ile Ile Leu Leu Thr Ile Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val His Ala Val Phe Ala Leu Arg Ala Arg Thr Val Thr Phe Gly
                 140                 145                 150

 Val Ile Thr Ser Ile Val Thr Trp Gly Leu Ala Val Leu Ala Ala
                 155                 160                 165

 Leu Pro Glu Phe Ile Phe Tyr Glu Thr Glu Glu Leu Phe Glu Glu
                 170                 175                 180

 Thr Leu Cys Ser Ala Leu Tyr Pro Glu Asp Thr Val Tyr Ser Trp
                 185                 190                 195

 Arg His Phe His Thr Leu Arg Met Thr Ile Phe Cys Leu Val Leu
                 200                 205                 210

 Pro Leu Leu Val Met Ala Ile Cys Tyr Thr Gly Ile Ile Lys Thr
                 215                 220                 225

 Leu Leu Arg Cys Pro Ser Lys Lys Lys Tyr Lys Ala Ile Arg Leu
                 230                 235                 240

 Ile Phe Val Ile Met Ala Val Phe Phe Ile Phe Trp Thr Pro Tyr
                 245                 250                 255

 Asn Val Ala Ile Leu Leu Ser Ser Tyr Gln Ser Ile Leu Phe Gly
                 260                 265                 270

 Asn Asp Cys Glu Arg Ser Lys His Leu Asp Leu Val Met Leu Val
                 275                 280                 285

 Thr Glu Val Ile Ala Tyr Ser His Cys Cys Met Asn Pro Val Ile
                 290                 295                 300

 Tyr Ala Phe Val Gly Glu Arg Phe Arg Lys Tyr Leu Arg His Phe
                 305                 310                 315

 Phe His Arg His Leu Leu Met His Leu Gly Arg Tyr Ile Pro Phe
                 320                 325                 330

 Leu Pro Ser Glu Lys Leu Glu Arg Thr Ser Ser Val Ser Pro Ser
                 335                 340                 345

 Thr Ala Glu Pro Glu Leu Ser Ile Val Phe
                 350                 355

<210> 5427
<211> 2139
<212> DNA
<213> Homo sapien

<400> 5427
 gtgagacagg ggtagtgcga ggccgggcac agccttcctg tgtggtttta 50

 ccgcccagag agcgtcatgg acctggggaa accaatgaaa agcgtgctgg 100

 tggtggctct ccttgtcatt ttccaggtat gcctgtgtca agatgaggtc 150

 acggacgatt acatcggaga caacaccaca gtggactaca ctttgttcga 200

 gtctttgtgc tccaagaagg acgtgcggaa ctttaaagcc tggttcctcc 250

 ctatcatgta ctccatcatt tgtttcgtgg gcctactggg caatgggctg 300

 gtcgtgttga cctatatcta tttcaagagg ctcaagacca tgaccgatac 350

 ctacctgctc aacctggcgg tggcagacat cctcttcctc ctgacccttc 400

 ccttctgggc ctacagcgcg gccaagtcct gggtcttcgg tgtccacttt 450

 tgcaagctca tctttgccat ctacaagatg agcttcttca gtggcatgct 500

 cctacttctt tgcatcagca ttgaccgcta cgtggccatc gtccaggctg 550

 tctcagctca ccgccaccgt gcccgcgtcc ttctcatcag caagctgtcc 600

 tgtgtgggca tctggatact agccacagtg ctctccatcc cagagctcct 650

 gtacagtgac ctccagagga gcagcagtga gcaagcgatg cgatgctctc 700

 tcatcacaga gcatgtggag gcctttatca ccatccaggt ggcccagatg 750

 gtgatcggct ttctggtccc cctgctggcc atgagcttct gttaccttgt 800

 catcatccgc accctgctcc aggcacgcaa ctttgagcgc aacaaggcca 850

 tcaaggtgat catcgctgtg gtcgtggtct tcatagtctt ccagctgccc 900

 tacaatgggg tggtcctggc ccagacggtg gccaacttca acatcaccag 950

 tagcacctgt gagctcagta agcaactcaa catcgcctac gacgtcacct 1000

 acagcctggc ctgcgtccgc tgctgcgtca accctttctt gtacgccttc 1050

 atcggcgtca agttccgcaa cgatctcttc aagctcttca aggacctggg 1100

 ctgcctcagc caggagcagc tccggcagtg gtcttcctgt cggcacatcc 1150

 ggcgctcctc catgagtgtg gaggccgaga ccaccaccac cttctcccca 1200

 taggcgactc ttctgcctgg actagaggga cctctcccag ggtccctggg 1250

 gtggggatag ggagcagatg caatgactca ggacatcccc ccgccaaaag 1300

 ctgctcaggg aaaagcagct ctcccctcag agtgcaagcc ctgctccaga 1350

 agttagcttc accccaatcc cagctacctc aaccaatgcc gaaaaagaca 1400

 gggctgataa gctaacacca gacagacaac actgggaaac agaggctatt 1450

 gtcccctaaa ccaaaaactg aaagtgaaag tccagaaact gttcccacct 1500

 gctggagtga aggggccaag gagggtgagt gcaaggggcg tgggagtggc 1550

 ctgaagagtc ctctgaatga accttctggc ctcccacaga ctcaaatgct 1600

 cagaccagct cttccgaaaa ccaggcctta tctccaagac cagagatagt 1650

 ggggagactt cttggcttgg tgaggaaaag cggacatcag ctggtcaaac 1700

 aaactctctg aacccctccc tccatcgttt tcttcactgt cctccaagcc 1750

 agcgggaatg gcagctgcca cgccgcccta aaagcacact catcccctca 1800

 cttgccgcgt cgccctccca ggctctcaac aggggagagt gtggtgtttc 1850

 ctgcaggcca ggccagctgc ctccgcgtga tcaaagccac actctgggct 1900

 ccagagtggg gatgacatgc actcagctct tggctccact gggatgggag 1950

 gagaggacaa gggaaatgtc aggggcgggg agggtgacag tggccgccca 2000

 aggccacgag cttgttcttt gttctttgtc acagggactg aaaacctctc 2050

 ctcatgttct gctttcgatt cgttaagaga gcaacatttt acccacacac 2100

 agataaagtt ttcccttgag gaaacaacag ctttaaaag 2139

<210> 5428
<211> 378
<212> PRT
<213> Homo sapien

<400> 5428
 Met Asp Leu Gly Lys Pro Met Lys Ser Val Leu Val Val Ala Leu
   1               5                  10                  15

 Leu Val Ile Phe Gln Val Cys Leu Cys Gln Asp Glu Val Thr Asp
                  20                  25                  30

 Asp Tyr Ile Gly Asp Asn Thr Thr Val Asp Tyr Thr Leu Phe Glu
                  35                  40                  45

 Ser Leu Cys Ser Lys Lys Asp Val Arg Asn Phe Lys Ala Trp Phe
                  50                  55                  60

 Leu Pro Ile Met Tyr Ser Ile Ile Cys Phe Val Gly Leu Leu Gly
                  65                  70                  75

 Asn Gly Leu Val Val Leu Thr Tyr Ile Tyr Phe Lys Arg Leu Lys
                  80                  85                  90

 Thr Met Thr Asp Thr Tyr Leu Leu Asn Leu Ala Val Ala Asp Ile
                  95                 100                 105

 Leu Phe Leu Leu Thr Leu Pro Phe Trp Ala Tyr Ser Ala Ala Lys
                 110                 115                 120

 Ser Trp Val Phe Gly Val His Phe Cys Lys Leu Ile Phe Ala Ile
                 125                 130                 135

 Tyr Lys Met Ser Phe Phe Ser Gly Met Leu Leu Leu Leu Cys Ile
                 140                 145                 150

 Ser Ile Asp Arg Tyr Val Ala Ile Val Gln Ala Val Ser Ala His
                 155                 160                 165

 Arg His Arg Ala Arg Val Leu Leu Ile Ser Lys Leu Ser Cys Val
                 170                 175                 180

 Gly Ile Trp Ile Leu Ala Thr Val Leu Ser Ile Pro Glu Leu Leu
                 185                 190                 195

 Tyr Ser Asp Leu Gln Arg Ser Ser Ser Glu Gln Ala Met Arg Cys
                 200                 205                 210

 Ser Leu Ile Thr Glu His Val Glu Ala Phe Ile Thr Ile Gln Val
                 215                 220                 225

 Ala Gln Met Val Ile Gly Phe Leu Val Pro Leu Leu Ala Met Ser
                 230                 235                 240

 Phe Cys Tyr Leu Val Ile Ile Arg Thr Leu Leu Gln Ala Arg Asn
                 245                 250                 255

 Phe Glu Arg Asn Lys Ala Ile Lys Val Ile Ile Ala Val Val Val
                 260                 265                 270

 Val Phe Ile Val Phe Gln Leu Pro Tyr Asn Gly Val Val Leu Ala
                 275                 280                 285

 Gln Thr Val Ala Asn Phe Asn Ile Thr Ser Ser Thr Cys Glu Leu
                 290                 295                 300

 Ser Lys Gln Leu Asn Ile Ala Tyr Asp Val Thr Tyr Ser Leu Ala
                 305                 310                 315

 Cys Val Arg Cys Cys Val Asn Pro Phe Leu Tyr Ala Phe Ile Gly
                 320                 325                 330

 Val Lys Phe Arg Asn Asp Leu Phe Lys Leu Phe Lys Asp Leu Gly
                 335                 340                 345

 Cys Leu Ser Gln Glu Gln Leu Arg Gln Trp Ser Ser Cys Arg His
                 350                 355                 360

 Ile Arg Arg Ser Ser Met Ser Val Glu Ala Glu Thr Thr Thr Thr
                 365                 370                 375

 Phe Ser Pro


<210> 5429
<211> 1431
<212> DNA
<213> Homo sapien

<400> 5429
 atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc 50

 tttgacagag agcaagtctg ctcatgtgca gactcagact gggcaaattt 100

 caatccctgc tttagctcag tgcagtgagc tgagatcagg caccagaaga 150

 ggctccccag ctgtaactct agtgcagtta ccttcgggcc aaactataca 200

 tgtccaggga gtaattcaga caccacagcc atgggttatt cagtcatcag 250

 aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca 300

 gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg 350

 aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg 400

 gtgttcccaa gattgaagaa gagagatcag aggaagaagg aacaccacct 450

 agtattgcta ccatggcagt accaactagc atatatcaga ctagcacggg 500

 gcaatacatt gctatagccc aaggtggaac aatccagatt tctaacccag 550

 gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga 600

 gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga 650

 tggcacacag cagttctttg tcccaggcag ccaggttgtt gttcaagctg 700

 ccactggtga catgccaact taccagatcc gagctcctac tgctgctttg 750

 ccacagggag tggtgatggc tgcatcgccc ggaagtttgc acagtcccca 800

 gcagctggca gaagaagcaa cacgcaaacg agagctgagg ctaatgaaaa 850

 acagagaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa 900

 tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat 950

 tgaggaactc aaggccctca aagatcttta ttgccataaa gtagagtaac 1000

 tgtctttgac ttggaccttg tttactctaa tcaaggcagg agatgcagca 1050

 gtcctactta ttgccatgtg gacttgtggg aaggacacgt gtgaccctta 1100

 agaatccagt ttggattagt gtttgaaatt gaattgggaa tgttgttcca 1150

 ggatgtggaa tgcagcgtga tcacacttac cgagcttact ttgatctgtt 1200

 tgtcaatagc atgcaaaaaa tgctttgttt gccctttgct tctgcttttt 1250

 ttcagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa 1300

 atgcctggag agccgagttg cagtgctgga agtccagaac aagaagctta 1350

 tagaggaact tgaaaccttg aaagacattt gttctcccaa aactgattac 1400

 tagaaatatt taactatgaa ctgattacag a 1431

<210> 5430
<211> 332
<212> PRT
<213> Homo sapien

<400> 5430
 Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr
   1               5                  10                  15

 Ala Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr
                  20                  25                  30

 Gly Gln Ile Ser Ile Pro Ala Leu Ala Gln Cys Ser Glu Leu Arg
                  35                  40                  45

 Ser Gly Thr Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu
                  50                  55                  60

 Pro Ser Gly Gln Thr Ile His Val Gln Gly Val Ile Gln Thr Pro
                  65                  70                  75

 Gln Pro Trp Val Ile Gln Ser Ser Glu Ile His Thr Val Gln Val
                  80                  85                  90

 Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly Val
                  95                 100                 105

 Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser
                 110                 115                 120

 Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val
                 125                 130                 135

 Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro
                 140                 145                 150

 Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser
                 155                 160                 165

 Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile
                 170                 175                 180

 Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr
                 185                 190                 195

 Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val Gln
                 200                 205                 210

 Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro
                 215                 220                 225

 Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr
                 230                 235                 240

 Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val
                 245                 250                 255

 Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala
                 260                 265                 270

 Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg
                 275                 280                 285

 Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys
                 290                 295                 300

 Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr
                 305                 310                 315

 Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys
                 320                 325                 330

 Val Glu


<210> 5431
<211> 1996
<212> DNA
<213> Homo sapien

<400> 5431
 tccggcaacg ccaaccgctc cgctgcgcgc aggctgggct gcaggctctc 50

 ggctgcagcg ctgggctggt gtgcagtggt gcgaccacgg ctcacggcag 100

 cctcagccac ccagatgtaa gcgatctggt tcccacctca gcctcccgag 150

 tagtggatct aggatccggc ttccaacatg tggcagctct gggcctccct 200

 ctgctgcctg ctggtgttgg ccaatgcccg gagcaggccc tctttccatc 250

 ccctgtcgga tgagctggtc aactatgtca acaaacggaa taccacgtgg 300

 caggccgggc acaacttcta caacgtggac atgagctact tgaagaggct 350

 atgtggtacc ttcctgggtg ggcccaagcc accccagaga gttatgttta 400

 ccgaggacct gaagctgcct gcaagcttcg atgcacggga acaatggcca 450

 cagtgtccca ccatcaaaga gatcagagac cagggctcct gtggctcctg 500

 ctgggccttc ggggctgtgg aagccatctc tgaccggatc tgcatccaca 550

 ccaatgcgca cgtcagcgtg gaggtgtcgg cggaggacct gctcacatgc 600

 tgtggcagca tgtgtgggga cggctgtaat ggtggctatc ctgctgaagc 650

 ttggaacttc tggacaagaa aaggcctggt ttctggtggc ctctatgaat 700

 cccatgtagg gtgcagaccg tactccatcc ctccctgtga gcaccacgtc 750

 aacggctccc ggcccccatg cacgggggag ggagataccc ccaagtgtag 800

 caagatctgt gagcctggct acagcccgac ctacaaacag gacaagcact 850

 acggatacaa ttcctacagc gtctccaata gcgagaagga catcatggcc 900

 gagatctaca aaaacggccc cgtggaggga gctttctctg tgtattcgga 950

 cttcctgctc tacaagtcag gagtgtacca acacgtcacc ggagagatga 1000

 tgggtggcca tgccatccgc atcctgggct ggggagtgga gaatggcaca 1050

 ccctactggc tggttgccaa ctcctggaac actgactggg gtgacaatgg 1100

 cttctttaaa atactcagag gacaggatca ctgtggaatc gaatcagaag 1150

 tggtggctgg aattccacgc accgatcagt actgggaaaa gatctaatct 1200

 gccgtgggcc tgtcgtgcca gtcctggggg cgagatcggg gtagaaatgc 1250

 attttattct ttaagttcac gtaagataca agtttcaggc agggtctgaa 1300

 ggactggatt ggccaaacat cagacctgtc ttccaaggag accaagtcct 1350

 ggctacatcc cagcctgtgg ttacagtgca gacaggccat gtgagccacc 1400

 gctgccagca cagagcgtcc ttccccctgt agactagtgc cgtgggagta 1450

 cctgctgccc agctgctgtg gccccctccg tgatccatcc atctccaggg 1500

 agcaagacag agacgcagga tggaaagcgg agttcctaac aggatgaaag 1550

 ttcccccatc agttccccca gtacctccaa gcaagtagct ttccacattt 1600

 gtcacagaaa tcagaggaga gatggtgttg ggagcccttt ggagaacgcc 1650

 agtctccagg tccccctgca tctatcgagt ttgcaatgtc acaacctctc 1700

 tgatcttgtg ctcagcatga ttctttaata gaagttttat ttttcgtgca 1750

 ctctgctaat catgtgggtg agccagtgga acagcgggag cctgtgctgg 1800

 tttgcagatt gcctcctaat gacgcggctc aaaaggaaac caagtggtca 1850

 ggagttgttt ctgacccact gatctctact accacaagga aaatagttta 1900

 ggagaaacca gcttttactg tttttgaaaa attacagctt caccctgtca 1950

 agttaacaag gaatgcctgt gccaataaaa ggtttctcca acttga 1996

<210> 5432
<211> 339
<212> PRT
<213> Homo sapien

<400> 5432
 Met Trp Gln Leu Trp Ala Ser Leu Cys Cys Leu Leu Val Leu Ala
   1               5                  10                  15

 Asn Ala Arg Ser Arg Pro Ser Phe His Pro Leu Ser Asp Glu Leu
                  20                  25                  30

 Val Asn Tyr Val Asn Lys Arg Asn Thr Thr Trp Gln Ala Gly His
                  35                  40                  45

 Asn Phe Tyr Asn Val Asp Met Ser Tyr Leu Lys Arg Leu Cys Gly
                  50                  55                  60

 Thr Phe Leu Gly Gly Pro Lys Pro Pro Gln Arg Val Met Phe Thr
                  65                  70                  75

 Glu Asp Leu Lys Leu Pro Ala Ser Phe Asp Ala Arg Glu Gln Trp
                  80                  85                  90

 Pro Gln Cys Pro Thr Ile Lys Glu Ile Arg Asp Gln Gly Ser Cys
                  95                 100                 105

 Gly Ser Cys Trp Ala Phe Gly Ala Val Glu Ala Ile Ser Asp Arg
                 110                 115                 120

 Ile Cys Ile His Thr Asn Ala His Val Ser Val Glu Val Ser Ala
                 125                 130                 135

 Glu Asp Leu Leu Thr Cys Cys Gly Ser Met Cys Gly Asp Gly Cys
                 140                 145                 150

 Asn Gly Gly Tyr Pro Ala Glu Ala Trp Asn Phe Trp Thr Arg Lys
                 155                 160                 165

 Gly Leu Val Ser Gly Gly Leu Tyr Glu Ser His Val Gly Cys Arg
                 170                 175                 180

 Pro Tyr Ser Ile Pro Pro Cys Glu His His Val Asn Gly Ser Arg
                 185                 190                 195

 Pro Pro Cys Thr Gly Glu Gly Asp Thr Pro Lys Cys Ser Lys Ile
                 200                 205                 210

 Cys Glu Pro Gly Tyr Ser Pro Thr Tyr Lys Gln Asp Lys His Tyr
                 215                 220                 225

 Gly Tyr Asn Ser Tyr Ser Val Ser Asn Ser Glu Lys Asp Ile Met
                 230                 235                 240

 Ala Glu Ile Tyr Lys Asn Gly Pro Val Glu Gly Ala Phe Ser Val
                 245                 250                 255

 Tyr Ser Asp Phe Leu Leu Tyr Lys Ser Gly Val Tyr Gln His Val
                 260                 265                 270

 Thr Gly Glu Met Met Gly Gly His Ala Ile Arg Ile Leu Gly Trp
                 275                 280                 285

 Gly Val Glu Asn Gly Thr Pro Tyr Trp Leu Val Ala Asn Ser Trp
                 290                 295                 300

 Asn Thr Asp Trp Gly Asp Asn Gly Phe Phe Lys Ile Leu Arg Gly
                 305                 310                 315

 Gln Asp His Cys Gly Ile Glu Ser Glu Val Val Ala Gly Ile Pro
                 320                 325                 330

 Arg Thr Asp Gln Tyr Trp Glu Lys Ile
                 335

<210> 5433
<211> 1600
<212> DNA
<213> Homo sapien

<400> 5433
 gccccgccgc cggcagtgga ccgctgtgcg cgaaccctga accctacggt 50

 cccgacccgc gggcgaggcc gggtacctgg gctgggatcc ggagcaagcg 100

 ggcgagggca gcgccctaag caggcccgga gcgatggcag ccttgatgac 150

 cccgggaacc ggggccccac ccgcgcctgg tgacttctcc ggggaaggga 200

 gccagggact tcccgaccct tcgccagagc ccaagcagct cccggagctg 250

 atccgcatga agcgagacgg aggccgcctg agcgaagcgg acatcagggg 300

 cttcgtggcc gctgtggtga atgggagcgc gcagggcgca cagatcgggg 350

 ccatgctgat ggccatccga cttcggggca tggatctgga ggagacctcg 400

 gtgctgaccc aggccctggc tcagtcggga cagcagctgg agtggccaga 450

 ggcctggcgc cagcagcttg tggacaagca ttccacaggg ggtgtgggtg 500

 acaaggtcag cctggtcctc gcacctgccc tggcggcatg tggctgcaag 550

 gtgccaatga tcagcggacg tggtctgggg cacacaggag gcaccttgga 600

 taagctggag tctattcctg gattcaatgt catccagagc ccagagcaga 650

 tgcaagtgct gctggaccag gcgggctgct gtatcgtggg tcagagtgag 700

 cagctggttc ctgcggacgg aatcctatat gcagccagag atgtgacagc 750

 caccgtggac agcctgccac tcatcacagc ctccattctc agtaagaaac 800

 tcgtggaggg gctgtccgct ctggtggtgg acgttaagtt cggaggggcc 850

 gccgtcttcc ccaaccagga gcaggcccgg gagctggcaa agacgctggt 900

 tggcgtggga gccagcctag ggcttcgggt cgcggcagcg ctgaccgcca 950

 tggacaagcc cctgggtcgc tgcgtgggcc acgccctgga ggtggaggag 1000

 gcgctgctct gcatggacgg cgcaggcccg ccagacttaa gggacctggt 1050

 caccacgctc gggggcgccc tgctctggct cagcggacac gcggggactc 1100

 aggctcaggg cgctgcccgg gtggccgcgg cgctggacga cggctcggcc 1150

 cttggccgct tcgagcggat gctggcggcg cagggcgtgg atcccggtct 1200

 ggcccgagcc ctgtgctcgg gaagtcccgc agaacgccgg cagctgctgc 1250

 ctcgcgcccg ggagcaggag gagctgctgg cgcccgcaga tggcaccgtg 1300

 gagctggtcc gggcgctgcc gctggcgctg gtgctgcacg agctcggggc 1350

 cgggcgcagc cgcgctgggg agccgctccg cctgggggtg ggcgcagagc 1400

 tgctggtcga cgtgggtcag aggctgcgcc gtgggacccc ctggctccgc 1450

 gtgcaccggg acggccccgc gctcagcggc ccgcagagcc gcgccctgca 1500

 ggaggcgctc gtactctccg accgcgcgcc attcgccgcc ccctcgccct 1550

 tcgcagagct cgttctgccg ccgcagcaat aaagctcctt tgccgcgaaa 1600

<210> 5434
<211> 482
<212> PRT
<213> Homo sapien

<400> 5434
 Met Ala Ala Leu Met Thr Pro Gly Thr Gly Ala Pro Pro Ala Pro
   1               5                  10                  15

 Gly Asp Phe Ser Gly Glu Gly Ser Gln Gly Leu Pro Asp Pro Ser
                  20                  25                  30

 Pro Glu Pro Lys Gln Leu Pro Glu Leu Ile Arg Met Lys Arg Asp
                  35                  40                  45

 Gly Gly Arg Leu Ser Glu Ala Asp Ile Arg Gly Phe Val Ala Ala
                  50                  55                  60

 Val Val Asn Gly Ser Ala Gln Gly Ala Gln Ile Gly Ala Met Leu
                  65                  70                  75

 Met Ala Ile Arg Leu Arg Gly Met Asp Leu Glu Glu Thr Ser Val
                  80                  85                  90

 Leu Thr Gln Ala Leu Ala Gln Ser Gly Gln Gln Leu Glu Trp Pro
                  95                 100                 105

 Glu Ala Trp Arg Gln Gln Leu Val Asp Lys His Ser Thr Gly Gly
                 110                 115                 120

 Val Gly Asp Lys Val Ser Leu Val Leu Ala Pro Ala Leu Ala Ala
                 125                 130                 135

 Cys Gly Cys Lys Val Pro Met Ile Ser Gly Arg Gly Leu Gly His
                 140                 145                 150

 Thr Gly Gly Thr Leu Asp Lys Leu Glu Ser Ile Pro Gly Phe Asn
                 155                 160                 165

 Val Ile Gln Ser Pro Glu Gln Met Gln Val Leu Leu Asp Gln Ala
                 170                 175                 180

 Gly Cys Cys Ile Val Gly Gln Ser Glu Gln Leu Val Pro Ala Asp
                 185                 190                 195

 Gly Ile Leu Tyr Ala Ala Arg Asp Val Thr Ala Thr Val Asp Ser
                 200                 205                 210

 Leu Pro Leu Ile Thr Ala Ser Ile Leu Ser Lys Lys Leu Val Glu
                 215                 220                 225

 Gly Leu Ser Ala Leu Val Val Asp Val Lys Phe Gly Gly Ala Ala
                 230                 235                 240

 Val Phe Pro Asn Gln Glu Gln Ala Arg Glu Leu Ala Lys Thr Leu
                 245                 250                 255

 Val Gly Val Gly Ala Ser Leu Gly Leu Arg Val Ala Ala Ala Leu
                 260                 265                 270

 Thr Ala Met Asp Lys Pro Leu Gly Arg Cys Val Gly His Ala Leu
                 275                 280                 285

 Glu Val Glu Glu Ala Leu Leu Cys Met Asp Gly Ala Gly Pro Pro
                 290                 295                 300

 Asp Leu Arg Asp Leu Val Thr Thr Leu Gly Gly Ala Leu Leu Trp
                 305                 310                 315

 Leu Ser Gly His Ala Gly Thr Gln Ala Gln Gly Ala Ala Arg Val
                 320                 325                 330

 Ala Ala Ala Leu Asp Asp Gly Ser Ala Leu Gly Arg Phe Glu Arg
                 335                 340                 345

 Met Leu Ala Ala Gln Gly Val Asp Pro Gly Leu Ala Arg Ala Leu
                 350                 355                 360

 Cys Ser Gly Ser Pro Ala Glu Arg Arg Gln Leu Leu Pro Arg Ala
                 365                 370                 375

 Arg Glu Gln Glu Glu Leu Leu Ala Pro Ala Asp Gly Thr Val Glu
                 380                 385                 390

 Leu Val Arg Ala Leu Pro Leu Ala Leu Val Leu His Glu Leu Gly
                 395                 400                 405

 Ala Gly Arg Ser Arg Ala Gly Glu Pro Leu Arg Leu Gly Val Gly
                 410                 415                 420

 Ala Glu Leu Leu Val Asp Val Gly Gln Arg Leu Arg Arg Gly Thr
                 425                 430                 435

 Pro Trp Leu Arg Val His Arg Asp Gly Pro Ala Leu Ser Gly Pro
                 440                 445                 450

 Gln Ser Arg Ala Leu Gln Glu Ala Leu Val Leu Ser Asp Arg Ala
                 455                 460                 465

 Pro Phe Ala Ala Pro Ser Pro Phe Ala Glu Leu Val Leu Pro Pro
                 470                 475                 480

 Gln Gln


<210> 5435
<211> 3132
<212> DNA
<213> Homo sapien

<400> 5435
 ccgcagaact tggggagccg ccgccgccat ccgccgccgc agccagcttc 50

 cgccgccgca ggaccggccc ctgccccagc ctccgcagcc gcggcgcgtc 100

 cacgcccgcc cgcgcccagg gcgagtcggg gtcgccgcct gcacgcttct 150

 cagtgttccc cgcgccccgc atgtaacccg gccaggcccc cgcaacggtg 200

 tcccctgcag ctccagcccc gggctgcacc cccccgcccc gacaccagct 250

 ctccagcctg ctcgtccagg atggccgcgg ccaaggccga gatgcagctg 300

 atgtccccgc tgcagatctc tgacccgttc ggatcctttc ctcactcgcc 350

 caccatggac aactacccta agctggagga gatgatgctg ctgagcaacg 400

 gggctcccca gttcctcggc gccgccgggg ccccagaggg cagcggcagc 450

 aacagcagca gcagcagcag cgggggcggt ggaggcggcg ggggcggcag 500

 caacagcagc agcagcagca gcaccttcaa ccctcaggcg gacacgggcg 550

 agcagcccta cgagcacctg accgcagagt cttttcctga catctctctg 600

 aacaacgaga aggtgctggt ggagaccagt taccccagcc aaaccactcg 650

 actgcccccc atcacctata ctggccgctt ttccctggag cctgcaccca 700

 acagtggcaa caccttgtgg cccgagcccc tcttcagctt ggtcagtggc 750

 ctagtgagca tgaccaaccc accggcctcc tcgtcctcag caccatctcc 800

 agcggcctcc tccgcctccg cctcccagag cccacccctg agctgcgcag 850

 tgccatccaa cgacagcagt cccatttact cagcggcacc caccttcccc 900

 acgccgaaca ctgacatttt ccctgagcca caaagccagg ccttcccggg 950

 ctcggcaggg acagcgctcc agtacccgcc tcctgcctac cctgccgcca 1000

 agggtggctt ccaggttccc atgatccccg actacctgtt tccacagcag 1050

 cagggggatc tgggcctggg caccccagac cagaagccct tccagggcct 1100

 ggagagccgc acccagcagc cttcgctaac ccctctgtct actattaagg 1150

 cctttgccac tcagtcgggc tcccaggacc tgaaggccct caataccagc 1200

 taccagtccc agctcatcaa acccagccgc atgcgcaagt atcccaaccg 1250

 gcccagcaag acgccccccc acgaacgccc ttacgcttgc ccagtggagt 1300

 cctgtgatcg ccgcttctcc cgctccgacg agctcacccg ccacatccgc 1350

 atccacacag gccagaagcc cttccagtgc cgcatctgca tgcgcaactt 1400

 cagccgcagc gaccacctca ccacccacat ccgcacccac acaggcgaaa 1450

 agcccttcgc ctgcgacatc tgtggaagaa agtttgccag gagcgatgaa 1500

 cgcaagaggc ataccaagat ccacttgcgg cagaaggaca agaaagcaga 1550

 caaaagtgtt gtggcctctt cggccacctc ctctctctct tcctacccgt 1600

 ccccggttgc tacctcttac ccgtccccgg ttactacctc ttatccatcc 1650

 ccggccacca cctcataccc atcccctgtg cccacctcct tctcctctcc 1700

 cggctcctcg acctacccat cccctgtgca cagtggcttc ccctccccgt 1750

 cggtggccac cacgtactcc tctgttcccc ctgctttccc ggcccaggtc 1800

 agcagcttcc cttcctcagc tgtcaccaac tccttcagcg cctccacagg 1850

 gctttcggac atgacagcaa ccttttctcc caggacaatt gaaatttgct 1900

 aaagggaaag gggaaagaaa gggaaaaggg agaaaaagaa acacaagaga 1950

 cttaaaggac aggaggagga gatggccata ggagaggagg gttcctctta 2000

 ggtcagatgg aggttctcag agccaagtcc tccctctcta ctggagtgga 2050

 aggtctattg gccaacaatc ctttctgccc acttcccctt ccccaattac 2100

 tattcccttt gacttcagct gcctgaaaca gccatgtcca agttcttcac 2150

 ctctatccaa agaacttgat ttgcatggat tttggataaa tcatttcagt 2200

 atcatctcca tcatatgcct gaccccttgc tcccttcaat gctagaaaat 2250

 cgagttggca aaatggggtt tgggcccctc agagccctgc cctgcaccct 2300

 tgtacagtgt ctgtgccatg gatttcgttt ttcttggggt actcttgatg 2350

 tgaagataat ttgcatattc tattgtatta tttggagtta ggtcctcact 2400

 tgggggaaaa aaaaaaaaaa aagccaagca aaccaatggt gatcctctat 2450

 tttgtgatga tgctgtgaca ataagtttga accttttttt ttgaaacagc 2500

 agtcccagta ttctcagagc atgtgtcaga gtgttgttcc gttaaccttt 2550

 ttgtaaatac tgcttgaccg tactctcaca tgtggcaaaa tatggtttgg 2600

 tttttctttt ttttttttga aagtgttttt tcttcgtcct tttggtttaa 2650

 aaagtttcac gtcttggtgc cttttgtgtg atgccccttg ctgatggctt 2700

 gacatgtgca attgtgaggg acatgctcac ctctagcctt aaggggggca 2750

 gggagtgatg atttggggga ggctttggga gcaaaataag gaagagggct 2800

 gagctgagct tcggttctcc agaatgtaag aaaacaaaat ctaaaacaaa 2850

 atctgaactc tcaaaagtct atttttttaa ctgaaaatgt aaatttataa 2900

 atatattcag gagttggaat gttgtagtta cctactgagt aggcggcgat 2950

 ttttgtatgt tatgaacatg cagttcatta ttttgtggtt ctattttact 3000

 ttgtacttgt gtttgcttaa acaaagtgac tgtttggctt ataaacacat 3050

 tgaatgcgct ttattgccca tgggatatgt ggtgtatatc cttccaaaaa 3100

 attaaaacga aaataaagta gctgcgattg gg 3132

<210> 5436
<211> 543
<212> PRT
<213> Homo sapien

<400> 5436
 Met Ala Ala Ala Lys Ala Glu Met Gln Leu Met Ser Pro Leu Gln
   1               5                  10                  15

 Ile Ser Asp Pro Phe Gly Ser Phe Pro His Ser Pro Thr Met Asp
                  20                  25                  30

 Asn Tyr Pro Lys Leu Glu Glu Met Met Leu Leu Ser Asn Gly Ala
                  35                  40                  45

 Pro Gln Phe Leu Gly Ala Ala Gly Ala Pro Glu Gly Ser Gly Ser
                  50                  55                  60

 Asn Ser Ser Ser Ser Ser Ser Gly Gly Gly Gly Gly Gly Gly Gly
                  65                  70                  75

 Gly Ser Asn Ser Ser Ser Ser Ser Ser Thr Phe Asn Pro Gln Ala
                  80                  85                  90

 Asp Thr Gly Glu Gln Pro Tyr Glu His Leu Thr Ala Glu Ser Phe
                  95                 100                 105

 Pro Asp Ile Ser Leu Asn Asn Glu Lys Val Leu Val Glu Thr Ser
                 110                 115                 120

 Tyr Pro Ser Gln Thr Thr Arg Leu Pro Pro Ile Thr Tyr Thr Gly
                 125                 130                 135

 Arg Phe Ser Leu Glu Pro Ala Pro Asn Ser Gly Asn Thr Leu Trp
                 140                 145                 150

 Pro Glu Pro Leu Phe Ser Leu Val Ser Gly Leu Val Ser Met Thr
                 155                 160                 165

 Asn Pro Pro Ala Ser Ser Ser Ser Ala Pro Ser Pro Ala Ala Ser
                 170                 175                 180

 Ser Ala Ser Ala Ser Gln Ser Pro Pro Leu Ser Cys Ala Val Pro
                 185                 190                 195

 Ser Asn Asp Ser Ser Pro Ile Tyr Ser Ala Ala Pro Thr Phe Pro
                 200                 205                 210

 Thr Pro Asn Thr Asp Ile Phe Pro Glu Pro Gln Ser Gln Ala Phe
                 215                 220                 225

 Pro Gly Ser Ala Gly Thr Ala Leu Gln Tyr Pro Pro Pro Ala Tyr
                 230                 235                 240

 Pro Ala Ala Lys Gly Gly Phe Gln Val Pro Met Ile Pro Asp Tyr
                 245                 250                 255

 Leu Phe Pro Gln Gln Gln Gly Asp Leu Gly Leu Gly Thr Pro Asp
                 260                 265                 270

 Gln Lys Pro Phe Gln Gly Leu Glu Ser Arg Thr Gln Gln Pro Ser
                 275                 280                 285

 Leu Thr Pro Leu Ser Thr Ile Lys Ala Phe Ala Thr Gln Ser Gly
                 290                 295                 300

 Ser Gln Asp Leu Lys Ala Leu Asn Thr Ser Tyr Gln Ser Gln Leu
                 305                 310                 315

 Ile Lys Pro Ser Arg Met Arg Lys Tyr Pro Asn Arg Pro Ser Lys
                 320                 325                 330

 Thr Pro Pro His Glu Arg Pro Tyr Ala Cys Pro Val Glu Ser Cys
                 335                 340                 345

 Asp Arg Arg Phe Ser Arg Ser Asp Glu Leu Thr Arg His Ile Arg
                 350                 355                 360

 Ile His Thr Gly Gln Lys Pro Phe Gln Cys Arg Ile Cys Met Arg
                 365                 370                 375

 Asn Phe Ser Arg Ser Asp His Leu Thr Thr His Ile Arg Thr His
                 380                 385                 390

 Thr Gly Glu Lys Pro Phe Ala Cys Asp Ile Cys Gly Arg Lys Phe
                 395                 400                 405

 Ala Arg Ser Asp Glu Arg Lys Arg His Thr Lys Ile His Leu Arg
                 410                 415                 420

 Gln Lys Asp Lys Lys Ala Asp Lys Ser Val Val Ala Ser Ser Ala
                 425                 430                 435

 Thr Ser Ser Leu Ser Ser Tyr Pro Ser Pro Val Ala Thr Ser Tyr
                 440                 445                 450

 Pro Ser Pro Val Thr Thr Ser Tyr Pro Ser Pro Ala Thr Thr Ser
                 455                 460                 465

 Tyr Pro Ser Pro Val Pro Thr Ser Phe Ser Ser Pro Gly Ser Ser
                 470                 475                 480

 Thr Tyr Pro Ser Pro Val His Ser Gly Phe Pro Ser Pro Ser Val
                 485                 490                 495

 Ala Thr Thr Tyr Ser Ser Val Pro Pro Ala Phe Pro Ala Gln Val
                 500                 505                 510

 Ser Ser Phe Pro Ser Ser Ala Val Thr Asn Ser Phe Ser Ala Ser
                 515                 520                 525

 Thr Gly Leu Ser Asp Met Thr Ala Thr Phe Ser Pro Arg Thr Ile
                 530                 535                 540

 Glu Ile Cys


<210> 5437
<211> 2423
<212> DNA
<213> Homo sapien

<400> 5437
 acccgcgctc gtacgtgcgc ctccgccggc agctcctgac tcatcggggg 50

 ctccgggtca catgcgcccg cgcggcccta taggcgcctc ctccgcccgc 100

 cgcccgggag ccgcagccgc cgccgccact gccactcccg ctctctcagc 150

 gccgccgtcg ccaccgccac cgccaccgcc actaccaccg tctgagtctg 200

 cagtcccgag atcccagcca tcatgtccat agagaagatc tgggcccggg 250

 agatcctgga ctcccgcggg aaccccacag tggaggtgga tctctatact 300

 gccaaaggtc ttttccgggc tgcagtgccc agtggagcct ctacgggcat 350

 ctatgaggcc ctggagctga gggatggaga caaacagcgt tacttaggca 400

 aaggtgtcct gaaggcagtg gaccacatca actccaccat cgcgccagcc 450

 ctcatcagct caggtctctc tgtggtggag caagagaaac tggacaacct 500

 gatgctggag ttggatggga ctgagaacaa atccaagttt ggggccaatg 550

 ccatcctggg tgtgtctctg gccgtgtgta aggcaggggc agctgagcgg 600

 gaactgcccc tgtatcgcca cattgctcag ctggccggga actcagacct 650

 catcctgcct gtgccggcct tcaacgtgat caatggtggc tctcatgctg 700

 gcaacaagct ggccatgcag gagttcatga tcctcccagt gggagctgag 750

 agctttcggg atgccatgcg actaggtgca gaggtctacc atacactcaa 800

 gggagtcatc aaggacaaat acggcaagga tgccaccaat gtgggggatg 850

 aaggtggctt tgcccccaat atcctggaga acagtgaagc cttggagctg 900

 gtgaaggaag ccatcgacaa ggctggctac acggaaaaga tcgttattgg 950

 catggatgtt gctgcctcag agttttatcg tgatggcaaa tatgacttgg 1000

 acttcaagtc tcccactgat ccttcccgat acatcactgg ggaccagctg 1050

 ggggcactct accaggactt tgtcagggac tatcctgtgg tctccattga 1100

 ggacccattt gaccaggatg attgggctgc ctggtccaag ttcacagcca 1150

 atgtagggat ccagattgtg ggtgatgacc tgacagtgac caacccaaaa 1200

 cgtattgagc gggcagtgga agaaaaggcc tgcaactgtc tgctgctcaa 1250

 ggtcaaccag atcggctcgg tcactgaagc catccaagcg tgcaagctgg 1300

 cccaggagaa tggctggggg gtcatggtga gtcatcgctc aggagagact 1350

 gaggacacat tcattgctga cctggtggtg gggctgtgca caggccagat 1400

 caagactggt gccccgtgcc gttctgaacg tctggctaaa tacaaccagc 1450

 tcatgagaat tgaggaagag ctgggggatg aagctcgctt tgccggacat 1500

 aacttccgta atcccagtgt gctgtgattc ctctgcttgc ctggagacgt 1550

 ggaacctctg tctcatcctc ctggaacctt gctgtcctga tctgtgatag 1600

 ttcaccccct gagatcccct gagccccagg gtgcccagaa cttccctgat 1650

 tgacctgctc cgctgctcct tggcttacct gacctcttgc tgtctctgct 1700

 cgccctcctt tctgtgccct actcattggg gttccgcact ttccacttct 1750

 tcctttctct ttctctcttc cctcagaaac tagaaatgtg aatgaggatt 1800

 attataaaag ggggtccgtg gaagaatgat cagcatctgt gatgggagcg 1850

 tcagggttgg tgtgctgagg tgttagagag ggaccatgtg tcacttgtgc 1900

 tttgctcttg tcccacgtgt cttccacttt gcatatgagc cgtgaactgt 1950

 gcatagtgct gggatggagg ggagtgttgg gcatgtgatc acgcctggct 2000

 aataaggctt tagtgtattt atttatttat ttattttatt tgtttttcat 2050

 tcatcccatt aatcatttcc ccataactca atggcctaaa actggcctga 2100

 cttgggggaa cgatgtgtct gtatttcatg tggctgtaga tcccaagatg 2150

 actggggtgg gaggtcttgc tagaatggga agggtcatag aaagggcctt 2200

 gacatcagtt cctttgtgtg tactcactga agcctgcgtt ggtccagagc 2250

 ggaggctgtg tgcctggggg agttttcctc tatacatctc tccccaaccc 2300

 taggttccct gttcttcctc cagctgcacc agagcaacct ctcactcccc 2350

 atgccacgtt ccacagttgc caccacctct gtggcattga aatgagcacc 2400

 tccattaaag tctgaatcag tgc 2423

<210> 5438
<211> 434
<212> PRT
<213> Homo sapien

<400> 5438
 Met Ser Ile Glu Lys Ile Trp Ala Arg Glu Ile Leu Asp Ser Arg
   1               5                  10                  15

 Gly Asn Pro Thr Val Glu Val Asp Leu Tyr Thr Ala Lys Gly Leu
                  20                  25                  30

 Phe Arg Ala Ala Val Pro Ser Gly Ala Ser Thr Gly Ile Tyr Glu
                  35                  40                  45

 Ala Leu Glu Leu Arg Asp Gly Asp Lys Gln Arg Tyr Leu Gly Lys
                  50                  55                  60

 Gly Val Leu Lys Ala Val Asp His Ile Asn Ser Thr Ile Ala Pro
                  65                  70                  75

 Ala Leu Ile Ser Ser Gly Leu Ser Val Val Glu Gln Glu Lys Leu
                  80                  85                  90

 Asp Asn Leu Met Leu Glu Leu Asp Gly Thr Glu Asn Lys Ser Lys
                  95                 100                 105

 Phe Gly Ala Asn Ala Ile Leu Gly Val Ser Leu Ala Val Cys Lys
                 110                 115                 120

 Ala Gly Ala Ala Glu Arg Glu Leu Pro Leu Tyr Arg His Ile Ala
                 125                 130                 135

 Gln Leu Ala Gly Asn Ser Asp Leu Ile Leu Pro Val Pro Ala Phe
                 140                 145                 150

 Asn Val Ile Asn Gly Gly Ser His Ala Gly Asn Lys Leu Ala Met
                 155                 160                 165

 Gln Glu Phe Met Ile Leu Pro Val Gly Ala Glu Ser Phe Arg Asp
                 170                 175                 180

 Ala Met Arg Leu Gly Ala Glu Val Tyr His Thr Leu Lys Gly Val
                 185                 190                 195

 Ile Lys Asp Lys Tyr Gly Lys Asp Ala Thr Asn Val Gly Asp Glu
                 200                 205                 210

 Gly Gly Phe Ala Pro Asn Ile Leu Glu Asn Ser Glu Ala Leu Glu
                 215                 220                 225

 Leu Val Lys Glu Ala Ile Asp Lys Ala Gly Tyr Thr Glu Lys Ile
                 230                 235                 240

 Val Ile Gly Met Asp Val Ala Ala Ser Glu Phe Tyr Arg Asp Gly
                 245                 250                 255

 Lys Tyr Asp Leu Asp Phe Lys Ser Pro Thr Asp Pro Ser Arg Tyr
                 260                 265                 270

 Ile Thr Gly Asp Gln Leu Gly Ala Leu Tyr Gln Asp Phe Val Arg
                 275                 280                 285

 Asp Tyr Pro Val Val Ser Ile Glu Asp Pro Phe Asp Gln Asp Asp
                 290                 295                 300

 Trp Ala Ala Trp Ser Lys Phe Thr Ala Asn Val Gly Ile Gln Ile
                 305                 310                 315

 Val Gly Asp Asp Leu Thr Val Thr Asn Pro Lys Arg Ile Glu Arg
                 320                 325                 330

 Ala Val Glu Glu Lys Ala Cys Asn Cys Leu Leu Leu Lys Val Asn
                 335                 340                 345

 Gln Ile Gly Ser Val Thr Glu Ala Ile Gln Ala Cys Lys Leu Ala
                 350                 355                 360

 Gln Glu Asn Gly Trp Gly Val Met Val Ser His Arg Ser Gly Glu
                 365                 370                 375

 Thr Glu Asp Thr Phe Ile Ala Asp Leu Val Val Gly Leu Cys Thr
                 380                 385                 390

 Gly Gln Ile Lys Thr Gly Ala Pro Cys Arg Ser Glu Arg Leu Ala
                 395                 400                 405

 Lys Tyr Asn Gln Leu Met Arg Ile Glu Glu Glu Leu Gly Asp Glu
                 410                 415                 420

 Ala Arg Phe Ala Gly His Asn Phe Arg Asn Pro Ser Val Leu
                 425                 430

<210> 5439
<211> 3592
<212> DNA
<213> Homo sapien

<400> 5439
 ggcggggggc gcacagagcc agaggggctt gcgagcggcg gctgagggac 50

 cgcggggagg gggcgccgag cggctccagc gcagagactc tcactgcacg 100

 ccggaggccc cttcctcgct ccgcccgcgc gaccgcgcgc cccagtcccg 150

 ccccgccccg ctaaccgccc cagacacagc gctcgccgag ggtcgcttgg 200

 accctgatct tacccgtggg caccctgcgc tctgcctgcc gcgaagaccg 250

 gctccccgac ccgcagaagt caggagagag ggtgaagcgg agcagcccga 300

 ggcggggcag cctcccggag cagcgccgcg cagagcccgg gacaatgggg 350

 ccgcggcggc tgctgctggt ggccgcctgc ttcagtctgt gcggcccgct 400

 gttgtctgcc cgcacccggg cccgcaggcc agaatcaaaa gcaacaaatg 450

 ccaccttaga tccccggtca tttcttctca ggaaccccaa tgataaatat 500

 gaaccatttt gggaggatga ggagaaaaat gaaagtgggt taactgaata 550

 cagattagtc tccatcaata aaagcagtcc tcttcaaaaa caacttcctg 600

 cattcatctc agaagatgcc tccggatatt tgaccagctc ctggctgaca 650

 ctctttgtcc catctgtgta caccggagtg tttgtagtca gcctcccact 700

 aaacatcatg gccatcgttg tgttcatcct gaaaatgaag gtcaagaagc 750

 cggcggtggt gtacatgctg cacctggcca cggcagatgt gctgtttgtg 800

 tctgtgctcc cctttaagat cagctattac ttttccggca gtgattggca 850

 gtttgggtct gaattgtgtc gcttcgtcac tgcagcattt tactgtaaca 900

 tgtacgcctc tatcttgctc atgacagtca taagcattga ccggtttctg 950

 gctgtggtgt atcccatgca gtccctctcc tggcgtactc tgggaagggc 1000

 ttccttcact tgtctggcca tctgggcttt ggccatcgca ggggtagtgc 1050

 ctctcgtcct caaggagcaa accatccagg tgcccgggct caacatcact 1100

 acctgtcatg atgtgctcaa tgaaaccctg ctcgaaggct actatgccta 1150

 ctacttctca gccttctctg ctgtcttctt ttttgtgccg ctgatcattt 1200

 ccacggtctg ttatgtgtct atcattcgat gtcttagctc ttccgcagtt 1250

 gccaaccgca gcaagaagtc ccgggctttg ttcctgtcag ctgctgtttt 1300

 ctgcatcttc atcatttgct tcggacccac aaacgtcctc ctgattgcgc 1350

 attactcatt cctttctcac acttccacca cagaggctgc ctactttgcc 1400

 tacctcctct gtgtctgtgt cagcagcata agctcgtgca tcgaccccct 1450

 aatttactat tacgcttcct ctgagtgcca gaggtacgtc tacagtatct 1500

 tatgctgcaa agaaagttcc gatcccagca gttataacag cagtgggcag 1550

 ttgatggcaa gtaaaatgga tacctgctct agtaacctga ataacagcat 1600

 atacaaaaag ctgttaactt aggaaaaggg actgctggga ggttaaaaag 1650

 aaaagtttat aaaagtgaat aacctgagga ttctattagt ccccacccaa 1700

 actttattga ttcacctcct aaaacaacag atgtacgact tgcatacctg 1750

 ctttttatgg gagctgtcaa gcatgtattt ttgtcaatta ccagaaagat 1800

 aacaggacga gatgacggtg ttattccaag ggaatattgc caatgctaca 1850

 gtaataaatg aatgtcactt ctggatatag ctaggtgaca tatacatact 1900

 tacatgtgtg tatatgtaga tgtatgcaca cacatatatt atttgcagtg 1950

 cagtatagaa taggcacttt aaaacactct ttccccgcac cccagcaatt 2000

 atgaaaataa tctctgattc cctgatttaa tatgcaaagt ctaggttggt 2050

 agagtttagc cctgaacatt tcatggtgtt catcaacagt gagagactcc 2100

 atagtttggg cttgtaccac ttttgcaaat aagtgtattt tgaaattgtt 2150

 tgacggcaag gtttaagtta ttaagaggta agacttagta ctatctgtgc 2200

 gtagaagttc tagtgttttc aattttaaac atatccaagt ttgaattcct 2250

 aaaattatgg aaacagatga aaagcctctg ttttgatatg ggtagtattt 2300

 tttacatttt acacactgta cacataagcc aaaactgagc ataagtcctc 2350

 tagtgaatgt aggctggctt tcagagtagg ctattcctga gagctgcatg 2400

 tgtccgcccc cgatggagga ctccaggcag cagacacatg ccagggccat 2450

 gtcagacaca gattggccag aaaccttcct gctgagcctc acagcagtga 2500

 gactggggcc actacatttg ctccatcctc ctgggattgg ctgtgaactg 2550

 atcatgttta tgagaaactg gcaaagcaga atgtgatatc ctaggaggta 2600

 atgaccatga aagacttctc tacccatctt aaaaacaacg aaagaaggca 2650

 tggacttctg gatgcccatc cactgggtgt aaacacatct agtagttgtt 2700

 ctgaaatgtc agttctgata tggaagcacc cattatgcgc tgtggccact 2750

 ccaataggtg ctgagtgtac agagtggaat aagacagaga cctgccctca 2800

 agagcaaagt agatcatgca tagagtgtga tgtatgtgta ataaatatgt 2850

 ttcacacaaa caaggcctgt cagctaaaga agtttgaaca tttgggttac 2900

 tatttcttgt ggttataact taatgaaaac aatgcagtac aggacatata 2950

 ttttttaaaa taagtctgat ttaattgggc actatttatt tacaaatgtt 3000

 ttgctcaata gattgctcaa atcaggtttt cttttaagaa tcaatcatgt 3050

 cagtctgctt agaaataaca gaagaaaata gaattgacat tgaaatctag 3100

 gaaaattatt ctataatttc catttactta agacttaatg agactttaaa 3150

 agcatttttt aacctcctaa gtatcaagta tagaaaatct tcatggaatt 3200

 cacaaagtaa tttggaaatt aggttgaaac atatctctta tcttacgaaa 3250

 aaatggtagc attttaaaca aaatagaaag ttgcaaggca aatgtttatt 3300

 taaaagagca ggccaggcgc ggtggctcac gcctgtaatc ccagcacttt 3350

 gggaggctga ggcgggtgga tcacgaggtc aggagatcga gaccatcctg 3400

 gctaacacgg tgaaacccgt ctctactaaa aatgcaaaaa aaattagccg 3450

 ggcgtggtgg caggcacctg tagtcccagc tactcgggag gctgaggcag 3500

 gagactggcg tgaacccagg aggcggacct tgtagtgagc cgagatcgcg 3550

 ccactgtgct ccagcctggg caacagagca agactccatc tc 3592

<210> 5440
<211> 425
<212> PRT
<213> Homo sapien

<400> 5440
 Met Gly Pro Arg Arg Leu Leu Leu Val Ala Ala Cys Phe Ser Leu
   1               5                  10                  15

 Cys Gly Pro Leu Leu Ser Ala Arg Thr Arg Ala Arg Arg Pro Glu
                  20                  25                  30

 Ser Lys Ala Thr Asn Ala Thr Leu Asp Pro Arg Ser Phe Leu Leu
                  35                  40                  45

 Arg Asn Pro Asn Asp Lys Tyr Glu Pro Phe Trp Glu Asp Glu Glu
                  50                  55                  60

 Lys Asn Glu Ser Gly Leu Thr Glu Tyr Arg Leu Val Ser Ile Asn
                  65                  70                  75

 Lys Ser Ser Pro Leu Gln Lys Gln Leu Pro Ala Phe Ile Ser Glu
                  80                  85                  90

 Asp Ala Ser Gly Tyr Leu Thr Ser Ser Trp Leu Thr Leu Phe Val
                  95                 100                 105

 Pro Ser Val Tyr Thr Gly Val Phe Val Val Ser Leu Pro Leu Asn
                 110                 115                 120

 Ile Met Ala Ile Val Val Phe Ile Leu Lys Met Lys Val Lys Lys
                 125                 130                 135

 Pro Ala Val Val Tyr Met Leu His Leu Ala Thr Ala Asp Val Leu
                 140                 145                 150

 Phe Val Ser Val Leu Pro Phe Lys Ile Ser Tyr Tyr Phe Ser Gly
                 155                 160                 165

 Ser Asp Trp Gln Phe Gly Ser Glu Leu Cys Arg Phe Val Thr Ala
                 170                 175                 180

 Ala Phe Tyr Cys Asn Met Tyr Ala Ser Ile Leu Leu Met Thr Val
                 185                 190                 195

 Ile Ser Ile Asp Arg Phe Leu Ala Val Val Tyr Pro Met Gln Ser
                 200                 205                 210

 Leu Ser Trp Arg Thr Leu Gly Arg Ala Ser Phe Thr Cys Leu Ala
                 215                 220                 225

 Ile Trp Ala Leu Ala Ile Ala Gly Val Val Pro Leu Val Leu Lys
                 230                 235                 240

 Glu Gln Thr Ile Gln Val Pro Gly Leu Asn Ile Thr Thr Cys His
                 245                 250                 255

 Asp Val Leu Asn Glu Thr Leu Leu Glu Gly Tyr Tyr Ala Tyr Tyr
                 260                 265                 270

 Phe Ser Ala Phe Ser Ala Val Phe Phe Phe Val Pro Leu Ile Ile
                 275                 280                 285

 Ser Thr Val Cys Tyr Val Ser Ile Ile Arg Cys Leu Ser Ser Ser
                 290                 295                 300

 Ala Val Ala Asn Arg Ser Lys Lys Ser Arg Ala Leu Phe Leu Ser
                 305                 310                 315

 Ala Ala Val Phe Cys Ile Phe Ile Ile Cys Phe Gly Pro Thr Asn
                 320                 325                 330

 Val Leu Leu Ile Ala His Tyr Ser Phe Leu Ser His Thr Ser Thr
                 335                 340                 345

 Thr Glu Ala Ala Tyr Phe Ala Tyr Leu Leu Cys Val Cys Val Ser
                 350                 355                 360

 Ser Ile Ser Ser Cys Ile Asp Pro Leu Ile Tyr Tyr Tyr Ala Ser
                 365                 370                 375

 Ser Glu Cys Gln Arg Tyr Val Tyr Ser Ile Leu Cys Cys Lys Glu
                 380                 385                 390

 Ser Ser Asp Pro Ser Ser Tyr Asn Ser Ser Gly Gln Leu Met Ala
                 395                 400                 405

 Ser Lys Met Asp Thr Cys Ser Ser Asn Leu Asn Asn Ser Ile Tyr
                 410                 415                 420

 Lys Lys Leu Leu Thr
                 425

<210> 5441
<211> 2881
<212> DNA
<213> Homo sapien

<400> 5441
 acagaagtgc tagaagccag tgctcgtgaa ctaaggagaa aaagaacaga 50

 caagggaaca gcctggacat ggcatcagag atccacatga caggcccaat 100

 gtgcctcatt gagaacacta atgggcgact gatggcgaat ccagaagctc 150

 tgaagatcct ttctgccatt acacagccta tggtggtggt ggcaattgtg 200

 ggcctctacc gcacaggcaa atcctacctg atgaacaagc tggctggaaa 250

 gaaaaagggc ttctctctgg gctccacggt gcagtctcac actaaaggaa 300

 tctggatgtg gtgtgtgccc caccccaaga agccaggcca catcctagtt 350

 ctgctggaca ccgagggtct gggagatgta gagaagggtg acaaccagaa 400

 tgactcctgg atcttcgccc tggccgtcct cctgagcagc accttcgtgt 450

 acaatagcat aggaaccatc aaccagcagg ctatggacca actgtactat 500

 gtgacagagc tgacacatag aatccgatca aaatcctcac ctgatgagaa 550

 tgagaatgag gttgaggatt cagctgactt tgtgagcttc ttcccagact 600

 ttgtgtggac actgagagat ttctccctgg acttggaagc agatggacaa 650

 cccctcacac cagatgagta cctgacatac tccctgaagc tgaagaaagg 700

 taccagtcaa aaagatgaaa cttttaacct gcccagactc tgtatccgga 750

 aattcttccc aaagaaaaaa tgctttgtct ttgatcggcc cgttcaccgc 800

 aggaagcttg cccagctcga gaaactacaa gatgaagagc tggaccccga 850

 atttgtgcaa caagtagcag acttctgttc ctacatcttt agtaattcca 900

 aaactaaaac tctttcagga ggcatccagg tcaacgggcc tcgtctagag 950

 agcctggtgc tgacctacgt caatgccatc agcagtgggg atctgccgtg 1000

 catggagaac gcagtcctgg ccttggccca gatagagaac tcagctgcag 1050

 tgcaaaaggc tattgcccac tatgaacagc agatgggcca gaaggtgcag 1100

 ctgcccacag aaagcctcca ggagctgctg gacctgcaca gggacagtga 1150

 gagagaggcc attgaagtct tcatcaggag ttccttcaaa gatgtggacc 1200

 atctatttca aaaggagtta gcggcccagc tagaaaaaaa gcgggatgac 1250

 ttttgtaaac agaatcagga agcatcatca gatcgttgct caggtttact 1300

 tcaggtcatt ttcagtcctc tagaagaaga agtgaaggcg ggaatttatt 1350

 cgaaaccagg gggctatcgt ctctttgttc agaagctaca agacctgaag 1400

 aaaaagtact atgaggaacc gaggaagggg atacaggctg aagagattct 1450

 gcagacatac ttgaaatcca aggagtctat gactgatgca attctccaga 1500

 cagaccagac tctcacagaa aaagaaaagg agattgaagt ggaacgtgtg 1550

 aaagctgagt ctgcacaggc ttcagcaaaa atgttgcagg aaatgcaaag 1600

 aaagaatgag cagatgatgg aacagaagga gaggagttat caggaacact 1650

 tgaaacaact gactgagaag atggagaacg acagggtcca gttgctgaaa 1700

 gagcaagaga ggaccctcgc tcttaaactt caggaacagg agcaactact 1750

 aaaagaggga tttcaaaaag aaagcagaat aatgaaaaat gagatacagg 1800

 atctccagac gaaaatgaga cgacgaaagg catgtaccat aagctaaaga 1850

 ccagagcctt cctgtcaccc ctaaccaagg cataattgaa acaattttag 1900

 aatttggaac aagcgtcact acatttgata ataattagat cttgcatcat 1950

 aacaccaaaa gtttataaag gcatgtggta caatgatcaa aatcatgttt 2000

 tttcttaaaa aaaaaaaaaa gactgtaaat tgtgcaacaa agatgcattt 2050

 acctctgtat caactcagga aatctcataa gctggtacca ctcaggagaa 2100

 gtttattctt ccagatgacc agcagtagac aaatggatac tgagcagagt 2150

 cttaggtaaa agtcttggga aatatttggg cattggtctg gccaagtcta 2200

 caatgtccca atatcaagga caaccaccct agcttcttag tgaagacaat 2250

 gtacagttat ccattagatc aagactacac ggtctatgag caataatgtg 2300

 atttctggac attgcccatg tataatcctc actgatgatt tcaagctaaa 2350

 gcaaaccacc ttatacagag atctagaatc tctttatgtt ctccagagga 2400

 aggtggaaga aaccatgggc aggagtagga attgagtgat aaacaattgg 2450

 gctaatgaag aaaacttctc ttattgttca gttcatccag attataactt 2500

 caatgggaca ctttagacca ttagacaatt gacactggat taaacaaatt 2550

 cacataatgc caaatacaca atgtatttat agcaacgtat aatttgcaaa 2600

 gatggacttt aaaagatgct gtgtaactaa actgaaataa ttcaattact 2650

 tattatttag aatgttaaag cttatgatag tcttttctaa ttcttaacac 2700

 tcatacttga aatctttccg agtttcccca gaagagaata tgggattttt 2750

 tttgacattt ttgacccatt taataatgct cttgtgttta cctagtatat 2800

 gtagactttg tcttatgtgt caaaagtcct aggaaagtgg ttgatgtttc 2850

 ttatagcaat taaaaattat ttttgaactg a 2881

<210> 5442
<211> 592
<212> PRT
<213> Homo sapien

<400> 5442
 Met Ala Ser Glu Ile His Met Thr Gly Pro Met Cys Leu Ile Glu
   1               5                  10                  15

 Asn Thr Asn Gly Arg Leu Met Ala Asn Pro Glu Ala Leu Lys Ile
                  20                  25                  30

 Leu Ser Ala Ile Thr Gln Pro Met Val Val Val Ala Ile Val Gly
                  35                  40                  45

 Leu Tyr Arg Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly
                  50                  55                  60

 Lys Lys Lys Gly Phe Ser Leu Gly Ser Thr Val Gln Ser His Thr
                  65                  70                  75

 Lys Gly Ile Trp Met Trp Cys Val Pro His Pro Lys Lys Pro Gly
                  80                  85                  90

 His Ile Leu Val Leu Leu Asp Thr Glu Gly Leu Gly Asp Val Glu
                  95                 100                 105

 Lys Gly Asp Asn Gln Asn Asp Ser Trp Ile Phe Ala Leu Ala Val
                 110                 115                 120

 Leu Leu Ser Ser Thr Phe Val Tyr Asn Ser Ile Gly Thr Ile Asn
                 125                 130                 135

 Gln Gln Ala Met Asp Gln Leu Tyr Tyr Val Thr Glu Leu Thr His
                 140                 145                 150

 Arg Ile Arg Ser Lys Ser Ser Pro Asp Glu Asn Glu Asn Glu Val
                 155                 160                 165

 Glu Asp Ser Ala Asp Phe Val Ser Phe Phe Pro Asp Phe Val Trp
                 170                 175                 180

 Thr Leu Arg Asp Phe Ser Leu Asp Leu Glu Ala Asp Gly Gln Pro
                 185                 190                 195

 Leu Thr Pro Asp Glu Tyr Leu Thr Tyr Ser Leu Lys Leu Lys Lys
                 200                 205                 210

 Gly Thr Ser Gln Lys Asp Glu Thr Phe Asn Leu Pro Arg Leu Cys
                 215                 220                 225

 Ile Arg Lys Phe Phe Pro Lys Lys Lys Cys Phe Val Phe Asp Arg
                 230                 235                 240

 Pro Val His Arg Arg Lys Leu Ala Gln Leu Glu Lys Leu Gln Asp
                 245                 250                 255

 Glu Glu Leu Asp Pro Glu Phe Val Gln Gln Val Ala Asp Phe Cys
                 260                 265                 270

 Ser Tyr Ile Phe Ser Asn Ser Lys Thr Lys Thr Leu Ser Gly Gly
                 275                 280                 285

 Ile Gln Val Asn Gly Pro Arg Leu Glu Ser Leu Val Leu Thr Tyr
                 290                 295                 300

 Val Asn Ala Ile Ser Ser Gly Asp Leu Pro Cys Met Glu Asn Ala
                 305                 310                 315

 Val Leu Ala Leu Ala Gln Ile Glu Asn Ser Ala Ala Val Gln Lys
                 320                 325                 330

 Ala Ile Ala His Tyr Glu Gln Gln Met Gly Gln Lys Val Gln Leu
                 335                 340                 345

 Pro Thr Glu Ser Leu Gln Glu Leu Leu Asp Leu His Arg Asp Ser
                 350                 355                 360

 Glu Arg Glu Ala Ile Glu Val Phe Ile Arg Ser Ser Phe Lys Asp
                 365                 370                 375

 Val Asp His Leu Phe Gln Lys Glu Leu Ala Ala Gln Leu Glu Lys
                 380                 385                 390

 Lys Arg Asp Asp Phe Cys Lys Gln Asn Gln Glu Ala Ser Ser Asp
                 395                 400                 405

 Arg Cys Ser Gly Leu Leu Gln Val Ile Phe Ser Pro Leu Glu Glu
                 410                 415                 420

 Glu Val Lys Ala Gly Ile Tyr Ser Lys Pro Gly Gly Tyr Arg Leu
                 425                 430                 435

 Phe Val Gln Lys Leu Gln Asp Leu Lys Lys Lys Tyr Tyr Glu Glu
                 440                 445                 450

 Pro Arg Lys Gly Ile Gln Ala Glu Glu Ile Leu Gln Thr Tyr Leu
                 455                 460                 465

 Lys Ser Lys Glu Ser Met Thr Asp Ala Ile Leu Gln Thr Asp Gln
                 470                 475                 480

 Thr Leu Thr Glu Lys Glu Lys Glu Ile Glu Val Glu Arg Val Lys
                 485                 490                 495

 Ala Glu Ser Ala Gln Ala Ser Ala Lys Met Leu Gln Glu Met Gln
                 500                 505                 510

 Arg Lys Asn Glu Gln Met Met Glu Gln Lys Glu Arg Ser Tyr Gln
                 515                 520                 525

 Glu His Leu Lys Gln Leu Thr Glu Lys Met Glu Asn Asp Arg Val
                 530                 535                 540

 Gln Leu Leu Lys Glu Gln Glu Arg Thr Leu Ala Leu Lys Leu Gln
                 545                 550                 555

 Glu Gln Glu Gln Leu Leu Lys Glu Gly Phe Gln Lys Glu Ser Arg
                 560                 565                 570

 Ile Met Lys Asn Glu Ile Gln Asp Leu Gln Thr Lys Met Arg Arg
                 575                 580                 585

 Arg Lys Ala Cys Thr Ile Ser
                 590

<210> 5443
<211> 2379
<212> DNA
<213> Homo sapien

<400> 5443
 ggaattccgg tcggcctctc gcccttcagc tacctgtgcg tccctccgtc 50

 ccgtcccgtc ccggggtcac cccggagcct gtccgctatg cggctcctgc 100

 ctctagcccc aggtcggctc cggcggggca gcccccgcca cctgccctcc 150

 tgcagcccag cgctgctact gctggtgctg ggcggctgcc tgggggtctt 200

 cggggtggct gcgggaaccc ggaggcccaa cgtggtgctg ctcctcacgg 250

 acgaccagga cgaagtgctc ggcggcatga caccactaaa gaaaaccaaa 300

 gctctcatcg gagagatggg gatgactttt tccagtgctt atgtgccaag 350

 tgctctctgc tgccccagca gagccagtat cctgacagga aagtacccac 400

 ataatcatca cgttgtgaac aacactctgg aggggaactg cagtagtaag 450

 tcctggcaga agatccaaga accaaatact ttcccagcaa ttctcagatc 500

 aatgtgtggt tatcagacct tttttgcagg gaaatattta aatgagtacg 550

 gagccccaga tgcaggtgga ctagaacacg ttcctctggg ttggagttac 600

 tggtatgcct tggaaaagaa ttctaagtat tataattaca ccctgtctat 650

 caatgggaag gcacggaagc atggtgaaaa ctatagtgtg gactacctga 700

 cagatgtttt ggctaatgtc tccttggact ttctggacta caagtccaac 750

 tttgagccct tcttcatgat gatcgccact ccagcgcctc attcgccttg 800

 gacagctgca cctcagtacc agaaggcttt ccagaatgtc tttgcaccaa 850

 gaaacaagaa cttcaacatc catggaacga acaagcactg gttaattagg 900

 caagccaaga ctccaatgac taattcttca atacagtttt tagataatgc 950

 atttaggaaa aggtggcaaa ctctcctctc agttgatgac cttgtggaga 1000

 aactggtcaa gaggctggag ttcactgggg agctcaacaa cacttacatc 1050

 ttctatacct cagacaatgg ctatcacaca ggacagtttt ccttgccaat 1100

 agacaagaga cagctgtatg agtttgatat caaagttcca ctgttggttc 1150

 gaggacctgg gatcaaacca aatcagacaa gcaagatgct ggttgccaac 1200

 attgacttgg gtcctactat tttggacatt gctggctacg acctaaataa 1250

 gacacagatg gatgggatgt ccttattgcc cattttgaga ggtgccagta 1300

 acttgacctg gcgatcagat gtcctggtgg aataccaagg agaaggccgt 1350

 aacgtcactg acccaacatg cccttccctg agtcctggcg tatctcaatg 1400

 cttcccagac tgtgtatgtg aagatgctta taacaatacc tatgcctgtg 1450

 tgaggacaat gtcagcattg tggaatttgc agtattgcga gtttgatgac 1500

 caggaggtgt ttgtagaagt ctataatctg actgcagacc cagaccagat 1550

 cactaacatt gctaaaacca tagacccaga gcttttagga aagatgaact 1600

 atcggttaat gatgttacag tcctgttctg ggccaacctg tcgcactcca 1650

 ggggtttttg accccggata caggtttgac ccccgtctca tgttcagcaa 1700

 tcgcggcagt gtcaggactc gaagattttc caaacatctt ctgtagcgac 1750

 ctcacacagc ctctgcagat ggatccctgc acgcctcttt ctgatgaagt 1800

 gattgtagta ggtgtctgta gctagtcttc aagaccacac ctggaagagt 1850

 ttctgggctg gctttaagtc ctgtttgaaa aagcaaccca gtcagctgac 1900

 ttcctcgtgc aatgtgttaa actgtgaact ctgcccatgt gtcaggagtg 1950

 gctgtctctg gtctcttcct ttagctgaca aggacactcc tgaggtcttt 2000

 gttctcactg tatttttttt atcctggggc cacagttctt gattattcct 2050

 cttgtggtta aagactgaat ttgtaaaccc attcagataa atggcagtac 2100

 tttaggacac acacaaacac acagatacac cttttgatat gtaagcttga 2150

 cctaaagtca aaggacctgt gtagcatttc agattgagca cttcactatc 2200

 aaaaatacta acatcacatg gcttgaagag taaccatcag agctgaatca 2250

 tccaagtaag aacaagtacc attgttgatt gataagtaga gatacatttt 2300

 ttatgatgtt catcacagtg tggtaaggtt gcaaattcaa aacatgtcac 2350

 ccaagctctg ttcatgtttt tgtgaattc 2379

<210> 5444
<211> 552
<212> PRT
<213> Homo sapien

<400> 5444
 Met Arg Leu Leu Pro Leu Ala Pro Gly Arg Leu Arg Arg Gly Ser
   1               5                  10                  15

 Pro Arg His Leu Pro Ser Cys Ser Pro Ala Leu Leu Leu Leu Val
                  20                  25                  30

 Leu Gly Gly Cys Leu Gly Val Phe Gly Val Ala Ala Gly Thr Arg
                  35                  40                  45

 Arg Pro Asn Val Val Leu Leu Leu Thr Asp Asp Gln Asp Glu Val
                  50                  55                  60

 Leu Gly Gly Met Thr Pro Leu Lys Lys Thr Lys Ala Leu Ile Gly
                  65                  70                  75

 Glu Met Gly Met Thr Phe Ser Ser Ala Tyr Val Pro Ser Ala Leu
                  80                  85                  90

 Cys Cys Pro Ser Arg Ala Ser Ile Leu Thr Gly Lys Tyr Pro His
                  95                 100                 105

 Asn His His Val Val Asn Asn Thr Leu Glu Gly Asn Cys Ser Ser
                 110                 115                 120

 Lys Ser Trp Gln Lys Ile Gln Glu Pro Asn Thr Phe Pro Ala Ile
                 125                 130                 135

 Leu Arg Ser Met Cys Gly Tyr Gln Thr Phe Phe Ala Gly Lys Tyr
                 140                 145                 150

 Leu Asn Glu Tyr Gly Ala Pro Asp Ala Gly Gly Leu Glu His Val
                 155                 160                 165

 Pro Leu Gly Trp Ser Tyr Trp Tyr Ala Leu Glu Lys Asn Ser Lys
                 170                 175                 180

 Tyr Tyr Asn Tyr Thr Leu Ser Ile Asn Gly Lys Ala Arg Lys His
                 185                 190                 195

 Gly Glu Asn Tyr Ser Val Asp Tyr Leu Thr Asp Val Leu Ala Asn
                 200                 205                 210

 Val Ser Leu Asp Phe Leu Asp Tyr Lys Ser Asn Phe Glu Pro Phe
                 215                 220                 225

 Phe Met Met Ile Ala Thr Pro Ala Pro His Ser Pro Trp Thr Ala
                 230                 235                 240

 Ala Pro Gln Tyr Gln Lys Ala Phe Gln Asn Val Phe Ala Pro Arg
                 245                 250                 255

 Asn Lys Asn Phe Asn Ile His Gly Thr Asn Lys His Trp Leu Ile
                 260                 265                 270

 Arg Gln Ala Lys Thr Pro Met Thr Asn Ser Ser Ile Gln Phe Leu
                 275                 280                 285

 Asp Asn Ala Phe Arg Lys Arg Trp Gln Thr Leu Leu Ser Val Asp
                 290                 295                 300

 Asp Leu Val Glu Lys Leu Val Lys Arg Leu Glu Phe Thr Gly Glu
                 305                 310                 315

 Leu Asn Asn Thr Tyr Ile Phe Tyr Thr Ser Asp Asn Gly Tyr His
                 320                 325                 330

 Thr Gly Gln Phe Ser Leu Pro Ile Asp Lys Arg Gln Leu Tyr Glu
                 335                 340                 345

 Phe Asp Ile Lys Val Pro Leu Leu Val Arg Gly Pro Gly Ile Lys
                 350                 355                 360

 Pro Asn Gln Thr Ser Lys Met Leu Val Ala Asn Ile Asp Leu Gly
                 365                 370                 375

 Pro Thr Ile Leu Asp Ile Ala Gly Tyr Asp Leu Asn Lys Thr Gln
                 380                 385                 390

 Met Asp Gly Met Ser Leu Leu Pro Ile Leu Arg Gly Ala Ser Asn
                 395                 400                 405

 Leu Thr Trp Arg Ser Asp Val Leu Val Glu Tyr Gln Gly Glu Gly
                 410                 415                 420

 Arg Asn Val Thr Asp Pro Thr Cys Pro Ser Leu Ser Pro Gly Val
                 425                 430                 435

 Ser Gln Cys Phe Pro Asp Cys Val Cys Glu Asp Ala Tyr Asn Asn
                 440                 445                 450

 Thr Tyr Ala Cys Val Arg Thr Met Ser Ala Leu Trp Asn Leu Gln
                 455                 460                 465

 Tyr Cys Glu Phe Asp Asp Gln Glu Val Phe Val Glu Val Tyr Asn
                 470                 475                 480

 Leu Thr Ala Asp Pro Asp Gln Ile Thr Asn Ile Ala Lys Thr Ile
                 485                 490                 495

 Asp Pro Glu Leu Leu Gly Lys Met Asn Tyr Arg Leu Met Met Leu
                 500                 505                 510

 Gln Ser Cys Ser Gly Pro Thr Cys Arg Thr Pro Gly Val Phe Asp
                 515                 520                 525

 Pro Gly Tyr Arg Phe Asp Pro Arg Leu Met Phe Ser Asn Arg Gly
                 530                 535                 540

 Ser Val Arg Thr Arg Arg Phe Ser Lys His Leu Leu
                 545                 550

<210> 5445
<211> 1040
<212> DNA
<213> Homo sapien

<400> 5445
 aacacatttc atctgggctt cttaaatcta aatctttaaa atgactaagt 50

 tttcttcctt ttctctgttt ttcctaatag ttggggctta tatgactcat 100

 gtgtgtttca atatggaaat tattggaggg aaagaagtgt cacctcattc 150

 caggccattt atggcctcca tccagtatgg cggacatcac gtttgtggag 200

 gtgttctgat tgatccacag tgggtgctga cagcagccca ctgccaatat 250

 cggtttacca aaggccagtc tcccactgtg gttttaggcg cacactctct 300

 ctcaaagaat gaggcctcca aacaaacact ggagatcaaa aaatttatac 350

 cattctcaag agttacatca gatcctcaat caaatgatat catgctggtt 400

 aagcttcaaa cagccgcaaa actcaataaa catgtcaaga tgctccacat 450

 aagatccaaa acctctctta gatctggaac caaatgcaag gttactggct 500

 ggggagccac cgatccagat tcattaagac cttctgacac cctgcgagaa 550

 gtcactgtta ctgtcctaag tcgaaaactt tgcaacagcc aaagttacta 600

 caacggcgac ccttttatca ccaaagacat ggtctgtgca ggagatgcca 650

 aaggccagaa ggattcctgt aagggtgact cagggggccc cttgatctgt 700

 aaaggtgtct tccacgctat agtctctgga ggtcatgaat gtggtgttgc 750

 cacaaagcct ggaatctaca ccctgttaac caagaaatac cagacttgga 800

 tcaaaagcaa ccttgtcccg cctcatacaa attaagttac aaataatttt 850

 attggatgca cttgcttctt ttttcctaat atgctcgcag gttagagttg 900

 ggtgtaagta aagcagagca catatggggt ccatttttgc acttgtaagt 950

 cattttatta aggaatcaag ttctttttca cttgtatcac tgatgtattt 1000

 ctaccatgct ggttttattc taaataaaat ttagaagact 1040

<210> 5446
<211> 264
<212> PRT
<213> Homo sapien

<400> 5446
 Met Thr Lys Phe Ser Ser Phe Ser Leu Phe Phe Leu Ile Val Gly
   1               5                  10                  15

 Ala Tyr Met Thr His Val Cys Phe Asn Met Glu Ile Ile Gly Gly
                  20                  25                  30

 Lys Glu Val Ser Pro His Ser Arg Pro Phe Met Ala Ser Ile Gln
                  35                  40                  45

 Tyr Gly Gly His His Val Cys Gly Gly Val Leu Ile Asp Pro Gln
                  50                  55                  60

 Trp Val Leu Thr Ala Ala His Cys Gln Tyr Arg Phe Thr Lys Gly
                  65                  70                  75

 Gln Ser Pro Thr Val Val Leu Gly Ala His Ser Leu Ser Lys Asn
                  80                  85                  90

 Glu Ala Ser Lys Gln Thr Leu Glu Ile Lys Lys Phe Ile Pro Phe
                  95                 100                 105

 Ser Arg Val Thr Ser Asp Pro Gln Ser Asn Asp Ile Met Leu Val
                 110                 115                 120

 Lys Leu Gln Thr Ala Ala Lys Leu Asn Lys His Val Lys Met Leu
                 125                 130                 135

 His Ile Arg Ser Lys Thr Ser Leu Arg Ser Gly Thr Lys Cys Lys
                 140                 145                 150

 Val Thr Gly Trp Gly Ala Thr Asp Pro Asp Ser Leu Arg Pro Ser
                 155                 160                 165

 Asp Thr Leu Arg Glu Val Thr Val Thr Val Leu Ser Arg Lys Leu
                 170                 175                 180

 Cys Asn Ser Gln Ser Tyr Tyr Asn Gly Asp Pro Phe Ile Thr Lys
                 185                 190                 195

 Asp Met Val Cys Ala Gly Asp Ala Lys Gly Gln Lys Asp Ser Cys
                 200                 205                 210

 Lys Gly Asp Ser Gly Gly Pro Leu Ile Cys Lys Gly Val Phe His
                 215                 220                 225

 Ala Ile Val Ser Gly Gly His Glu Cys Gly Val Ala Thr Lys Pro
                 230                 235                 240

 Gly Ile Tyr Thr Leu Leu Thr Lys Lys Tyr Gln Thr Trp Ile Lys
                 245                 250                 255

 Ser Asn Leu Val Pro Pro His Thr Asn
                 260

<210> 5447
<211> 1550
<212> DNA
<213> Homo sapien

<400> 5447
 tcaacgcctg cctcccctcg agcgtcctca gcgcagccgc cgcccgcgga 50

 gccagcacga acgagcccag caccggccgg atggagcgtc cgcaacccga 100

 cagcatgccc caggatttgt cagaggccct gaaggaggcc accaaggagg 150

 tgcacaccca ggcagagaat gctgagttca tgaggaactt tcagaagggc 200

 caggtgaccc gagacggctt caagctggtg atggcctccc tgtaccacat 250

 ctatgtggcc ctggaggagg agattgagcg caacaaggag agcccagtct 300

 tcgcccctgt ctacttccca gaagagctgc accgcaaggc tgccctggag 350

 caggacctgg ccttctggta cgggccccgc tggcaggagg tcatccccta 400

 cacaccagcc atgcagcgct atgtgaagcg gctccacgag gtggggcgca 450

 cagagcccga gctgctggtg gcccacgcct acacccgcta cctgggtgac 500

 ctgtctgggg gccaggtgct caaaaagatt gcccagaaag ccctggacct 550

 gcccagctct ggcgagggcc tggccttctt caccttcccc aacattgcca 600

 gtgccaccaa gttcaagcag ctctaccgct cccgcatgaa ctccctggag 650

 atgactcccg cagtcaggca gagggtgata gaagaggcca agactgcgtt 700

 cctgctcaac atccagctct ttgaggagtt gcaggagctg ctgacccatg 750

 acaccaagga ccagagcccc tcacgggcac cagggcttcg ccagcgggcc 800

 agcaacaaag tgcaagattc tgcccccgtg gagactccca gagggaagcc 850

 cccactcaac acccgctccc aggctccgct tctccgatgg gtccttacac 900

 tcagctttct ggtggcgaca gttgctgtag ggctttatgc catgtgaatg 950

 caggcatgct ggctcccagg gccatgaact ttgtccggtg gaaggccttc 1000

 tttctagaga gggaattctc ttggctggct tccttaccgt gggcactgaa 1050

 ggctttcagg gcctccagcc ctctcactgt gtccctctct ctggaaagga 1100

 ggaaggagcc tatggcatct tccccaacga aaagcacatc caggcaatgg 1150

 cctaaacttc agagggggcg aaggggtcag ccctgccctt cagcatcctc 1200

 agttcctgca gcagagcctg gaagacaccc taatgtggca gctgtctcaa 1250

 acctccaaaa gccctgagtt tcaagtatcc ttgttgacac ggccatgacc 1300

 actttccccg tgggccatgg caatttttac acaaacctga aaagatgttg 1350

 tgtcttgtgt ttttgtctta tttttgttgg agccactctg ttcctggctc 1400

 agcctcaaat gcagtatttt tgttgtgttc tgttgttttt atagcagggt 1450

 tggggtggtt tttgagccat gcgtgggtgg ggagggaggt gtttaacggc 1500

 actgtggcct tggtctaact tttgtgtgaa ataataaaca acattgtctg 1550

<210> 5448
<211> 288
<212> PRT
<213> Homo sapien

<400> 5448
 Met Glu Arg Pro Gln Pro Asp Ser Met Pro Gln Asp Leu Ser Glu
   1               5                  10                  15

 Ala Leu Lys Glu Ala Thr Lys Glu Val His Thr Gln Ala Glu Asn
                  20                  25                  30

 Ala Glu Phe Met Arg Asn Phe Gln Lys Gly Gln Val Thr Arg Asp
                  35                  40                  45

 Gly Phe Lys Leu Val Met Ala Ser Leu Tyr His Ile Tyr Val Ala
                  50                  55                  60

 Leu Glu Glu Glu Ile Glu Arg Asn Lys Glu Ser Pro Val Phe Ala
                  65                  70                  75

 Pro Val Tyr Phe Pro Glu Glu Leu His Arg Lys Ala Ala Leu Glu
                  80                  85                  90

 Gln Asp Leu Ala Phe Trp Tyr Gly Pro Arg Trp Gln Glu Val Ile
                  95                 100                 105

 Pro Tyr Thr Pro Ala Met Gln Arg Tyr Val Lys Arg Leu His Glu
                 110                 115                 120

 Val Gly Arg Thr Glu Pro Glu Leu Leu Val Ala His Ala Tyr Thr
                 125                 130                 135

 Arg Tyr Leu Gly Asp Leu Ser Gly Gly Gln Val Leu Lys Lys Ile
                 140                 145                 150

 Ala Gln Lys Ala Leu Asp Leu Pro Ser Ser Gly Glu Gly Leu Ala
                 155                 160                 165

 Phe Phe Thr Phe Pro Asn Ile Ala Ser Ala Thr Lys Phe Lys Gln
                 170                 175                 180

 Leu Tyr Arg Ser Arg Met Asn Ser Leu Glu Met Thr Pro Ala Val
                 185                 190                 195

 Arg Gln Arg Val Ile Glu Glu Ala Lys Thr Ala Phe Leu Leu Asn
                 200                 205                 210

 Ile Gln Leu Phe Glu Glu Leu Gln Glu Leu Leu Thr His Asp Thr
                 215                 220                 225

 Lys Asp Gln Ser Pro Ser Arg Ala Pro Gly Leu Arg Gln Arg Ala
                 230                 235                 240

 Ser Asn Lys Val Gln Asp Ser Ala Pro Val Glu Thr Pro Arg Gly
                 245                 250                 255

 Lys Pro Pro Leu Asn Thr Arg Ser Gln Ala Pro Leu Leu Arg Trp
                 260                 265                 270

 Val Leu Thr Leu Ser Phe Leu Val Ala Thr Val Ala Val Gly Leu
                 275                 280                 285

 Tyr Ala Met


<210> 5449
<211> 1824
<212> DNA
<213> Homo sapien

<400> 5449
 cagctctctg tcagaatggc caccatggta ccatccgtgt tgtggcccag 50

 ggcctgctgg actctgctgg tctgctgtct gctgacccca ggtgtccagg 100

 ggcaggagtt ccttttgcgg gtggagcccc agaaccctgt gctctctgct 150

 ggagggtccc tgtttgtgaa ctgcagtact gattgtccca gctctgagaa 200

 aatcgccttg gagacgtccc tatcaaagga gctggtggcc agtggcatgg 250

 gctgggcagc cttcaatctc agcaacgtga ctggcaacag tcggatcctc 300

 tgctcagtgt actgcaatgg ctcccagata acaggctcct ctaacatcac 350

 cgtgtacggg ctcccggagc gtgtggagct ggcacccctg cctccttggc 400

 agccggtggg ccagaacttc accctgcgct gccaagtgga gggtgggtcg 450

 ccccggacca gcctcacggt ggtgctgctt cgctgggagg aggagctgag 500

 ccggcagccc gcagtggagg agccagcgga ggtcactgcc actgtgctgg 550

 ccagcagaga cgaccacgga gcccctttct catgccgcac agaactggac 600

 atgcagcccc aggggctggg actgttcgtg aacacctcag ccccccgcca 650

 gctccgaacc tttgtcctgc ccgtgacccc cccgcgcctc gtggcccccc 700

 ggttcttgga ggtggaaacg tcgtggccgg tggactgcac cctagacggg 750

 ctttttccag cctcagaggc ccaggtctac ctggcgctgg gggaccagat 800

 gctgaatgcg acagtcatga accacgggga cacgctaacg gccacagcca 850

 cagccacggc gcgcgcggat caggagggtg cccgggagat cgtctgcaac 900

 gtgaccctag ggggcgagag acgggaggcc cgggagaact tgacggtctt 950

 tagcttccta ggacccattg tgaacctcag cgagcccacc gcccatgagg 1000

 ggtccacagt gaccgtgagt tgcatggctg gggctcgagt ccaggtcacg 1050

 ctggacggag ttccggccgc ggccccgggg cagccagctc aacttcagct 1100

 aaatgctacc gagagtgacg acggacgcag cttcttctgc agtgccactc 1150

 tcgaggtgga cggcgagttc ttgcacagga acagtagcgt ccagctgcga 1200

 gtcctgtatg gtcccaaaat tgaccgagcc acatgccccc agcacttgaa 1250

 atggaaagat aaaacgagac acgtcctgca gtgccaagcc aggggcaacc 1300

 cgtaccccga gctgcggtgt ttgaaggaag gctccagccg ggaggtgccg 1350

 gtggggatcc cgttcttcgt caacgtaaca cataatggta cttatcagtg 1400

 ccaagcgtcc agctcacgag gcaaatacac cctggtcgtg gtgatggaca 1450

 ttgaggctgg gagctcccac tttgtccccg tcttcgtggc ggtgttactg 1500

 accctgggcg tggtgactat cgtactggcc ttaatgtacg tcttcaggga 1550

 gcaccaacgg agcggcagtt accatgttag ggaggagagc acctatctgc 1600

 ccctcacgtc tatgcagccg acagaagcaa tgggggaaga accgtccaga 1650

 gctgagtgac gctgggatcc gggatcaaag ttggcggggg cttggctgtg 1700

 ccctcagatt ccgcaccaat aaagccttca aactccctaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800

 aaaaaaaaaa aaaaaaaaaa aaaa 1824

<210> 5450
<211> 547
<212> PRT
<213> Homo sapien

<400> 5450
 Met Ala Thr Met Val Pro Ser Val Leu Trp Pro Arg Ala Cys Trp
   1               5                  10                  15

 Thr Leu Leu Val Cys Cys Leu Leu Thr Pro Gly Val Gln Gly Gln
                  20                  25                  30

 Glu Phe Leu Leu Arg Val Glu Pro Gln Asn Pro Val Leu Ser Ala
                  35                  40                  45

 Gly Gly Ser Leu Phe Val Asn Cys Ser Thr Asp Cys Pro Ser Ser
                  50                  55                  60

 Glu Lys Ile Ala Leu Glu Thr Ser Leu Ser Lys Glu Leu Val Ala
                  65                  70                  75

 Ser Gly Met Gly Trp Ala Ala Phe Asn Leu Ser Asn Val Thr Gly
                  80                  85                  90

 Asn Ser Arg Ile Leu Cys Ser Val Tyr Cys Asn Gly Ser Gln Ile
                  95                 100                 105

 Thr Gly Ser Ser Asn Ile Thr Val Tyr Gly Leu Pro Glu Arg Val
                 110                 115                 120

 Glu Leu Ala Pro Leu Pro Pro Trp Gln Pro Val Gly Gln Asn Phe
                 125                 130                 135

 Thr Leu Arg Cys Gln Val Glu Gly Gly Ser Pro Arg Thr Ser Leu
                 140                 145                 150

 Thr Val Val Leu Leu Arg Trp Glu Glu Glu Leu Ser Arg Gln Pro
                 155                 160                 165

 Ala Val Glu Glu Pro Ala Glu Val Thr Ala Thr Val Leu Ala Ser
                 170                 175                 180

 Arg Asp Asp His Gly Ala Pro Phe Ser Cys Arg Thr Glu Leu Asp
                 185                 190                 195

 Met Gln Pro Gln Gly Leu Gly Leu Phe Val Asn Thr Ser Ala Pro
                 200                 205                 210

 Arg Gln Leu Arg Thr Phe Val Leu Pro Val Thr Pro Pro Arg Leu
                 215                 220                 225

 Val Ala Pro Arg Phe Leu Glu Val Glu Thr Ser Trp Pro Val Asp
                 230                 235                 240

 Cys Thr Leu Asp Gly Leu Phe Pro Ala Ser Glu Ala Gln Val Tyr
                 245                 250                 255

 Leu Ala Leu Gly Asp Gln Met Leu Asn Ala Thr Val Met Asn His
                 260                 265                 270

 Gly Asp Thr Leu Thr Ala Thr Ala Thr Ala Thr Ala Arg Ala Asp
                 275                 280                 285

 Gln Glu Gly Ala Arg Glu Ile Val Cys Asn Val Thr Leu Gly Gly
                 290                 295                 300

 Glu Arg Arg Glu Ala Arg Glu Asn Leu Thr Val Phe Ser Phe Leu
                 305                 310                 315

 Gly Pro Ile Val Asn Leu Ser Glu Pro Thr Ala His Glu Gly Ser
                 320                 325                 330

 Thr Val Thr Val Ser Cys Met Ala Gly Ala Arg Val Gln Val Thr
                 335                 340                 345

 Leu Asp Gly Val Pro Ala Ala Ala Pro Gly Gln Pro Ala Gln Leu
                 350                 355                 360

 Gln Leu Asn Ala Thr Glu Ser Asp Asp Gly Arg Ser Phe Phe Cys
                 365                 370                 375

 Ser Ala Thr Leu Glu Val Asp Gly Glu Phe Leu His Arg Asn Ser
                 380                 385                 390

 Ser Val Gln Leu Arg Val Leu Tyr Gly Pro Lys Ile Asp Arg Ala
                 395                 400                 405

 Thr Cys Pro Gln His Leu Lys Trp Lys Asp Lys Thr Arg His Val
                 410                 415                 420

 Leu Gln Cys Gln Ala Arg Gly Asn Pro Tyr Pro Glu Leu Arg Cys
                 425                 430                 435

 Leu Lys Glu Gly Ser Ser Arg Glu Val Pro Val Gly Ile Pro Phe
                 440                 445                 450

 Phe Val Asn Val Thr His Asn Gly Thr Tyr Gln Cys Gln Ala Ser
                 455                 460                 465

 Ser Ser Arg Gly Lys Tyr Thr Leu Val Val Val Met Asp Ile Glu
                 470                 475                 480

 Ala Gly Ser Ser His Phe Val Pro Val Phe Val Ala Val Leu Leu
                 485                 490                 495

 Thr Leu Gly Val Val Thr Ile Val Leu Ala Leu Met Tyr Val Phe
                 500                 505                 510

 Arg Glu His Gln Arg Ser Gly Ser Tyr His Val Arg Glu Glu Ser
                 515                 520                 525

 Thr Tyr Leu Pro Leu Thr Ser Met Gln Pro Thr Glu Ala Met Gly
                 530                 535                 540

 Glu Glu Pro Ser Arg Ala Glu
                 545

<210> 5451
<211> 4726
<212> DNA
<213> Homo sapien

<400> 5451
 tgccgggatc caggtctccg gggtccgctt tggccagagg cgcggaagga 50

 agcagtgccc ggcgacactg cacccatccc ggctgctttt gctgcgccct 100

 ctcagcttcc caagaaaggc atcgtcatgt gatcatcacc taagaactag 150

 aacatcagca ggccctagaa gcctcactct tgcccctccc tttaatatct 200

 caaaggatga cacttctgtg gtgtgtagtg agtctctact tttatggaat 250

 cctgcaaagt gatgcctcag aacgctgcga tgactgggga ctagacacca 300

 tgaggcaaat ccaagtgttt gaagatgagc cagctcgcat caagtgccca 350

 ctctttgaac acttcttgaa attcaactac agcacagccc attcagctgg 400

 ccttactctg atctggtatt ggactaggca ggaccgggac cttgaggagc 450

 caattaactt ccgcctcccc gagaaccgca ttagtaagga gaaagatgtg 500

 ctgtggttcc ggcccactct cctcaatgac actggcaact atacctgcat 550

 gttaaggaac actacatatt gcagcaaagt tgcatttccc ttggaagttg 600

 ttcaaaaaga cagctgtttc aattccccca tgaaactccc agtgcataaa 650

 ctgtatatag aatatggcat tcagaggatc acttgtccaa atgtagatgg 700

 atattttcct tccagtgtca aaccgactat cacttggtat atgggctgtt 750

 ataaaataca gaattttaat aatgtaatac ccgaaggtat gaacttgagt 800

 ttcctcattg ccttaatttc aaataatgga aattacacat gtgttgttac 850

 atatccagaa aatggacgta cgtttcatct caccaggact ctgactgtaa 900

 aggtagtagg ctctccaaaa aatgcagtgc cccctgtgat ccattcacct 950

 aatgatcatg tggtctatga gaaagaacca ggagaggagc tactcattcc 1000

 ctgtacggtc tattttagtt ttctgatgga ttctcgcaat gaggtttggt 1050

 ggaccattga tggaaaaaaa cctgatgaca tcactattga tgtcaccatt 1100

 aacgaaagta taagtcatag tagaacagaa gatgaaacaa gaactcagat 1150

 tttgagcatc aagaaagtta cctctgagga tctcaagcgc agctatgtct 1200

 gtcatgctag aagtgccaaa ggcgaagttg ccaaagcagc caaggtgaag 1250

 cagaaagtgc cagctccaag atacacagtg gaactggctt gtggttttgg 1300

 agccacagtc ctgctagtgg tgattctcat tgttgtttac catgtttact 1350

 ggctagagat ggtcctattt taccgggctc attttggaac agatgaaacc 1400

 attttagatg gaaaagagta tgatatttat gtatcctatg caaggaatgc 1450

 ggaagaagaa gaatttgtat tactgaccct ccgtggagtt ttggagaatg 1500

 aatttggata caagctgtgc atctttgacc gagacagtct gcctggggga 1550

 attgtcacag atgagacttt gagcttcatt cagaaaagca gacgcctcct 1600

 ggttgttcta agccccaact acgtgctcca gggaacccaa gccctcctgg 1650

 agctcaaggc tggcctagaa aatatggcct ctcggggcaa catcaacgtc 1700

 attttagtac agtacaaagc tgtgaaggaa acgaaggtga aagagctgaa 1750

 gagggctaag acggtgctca cggtcattaa atggaaaggg gaaaaatcca 1800

 agtatccaca gggcaggttc tggaagcagc tgcaggtggc catgccagtg 1850

 aagaaaagtc ccaggcggtc tagcagtgat gagcagggcc tctcgtattc 1900

 atctttgaaa aatgtatgaa aggaataatg aaaagggtaa aaagaacaag 1950

 gggtgctcca ggaagaaaga gtccccccag tcttcattcg cagtttatgg 2000

 tttcataggc aaaaataatg gtctaagcct cccaataggg ataaatttag 2050

 ggtgactgtg tggctgacta ttctgcttcc tcaggcaaca ctaaagttta 2100

 gaaagatatc atcaacgttc tgtcaccagt ctctgatgcc actatgttct 2150

 ttgcaggcaa agacttgttc aatgcgaatt tccccttcta cattgtctat 2200

 ccctgttttt atatgtctcc attcttttta aaatcttaac atatggagca 2250

 gcctttccta tgaatttaaa tatgccttta aaataagtca ctgttgacag 2300

 ggtcatgagt ttccgagtat agttttcttt ttatcttatt tttactcgtc 2350

 cgttgaaaag ataatcaagg cctacatttt agctgaggat aatgaacttt 2400

 tttcctcatt cggctgtata atacataacc acagcaagac tgacatccac 2450

 ttaggatgat acaaagcagt gtaactgaaa atgtttcttt taattgattt 2500

 aaaggacttg tcttctatac cacccttgtc ctcatctcag gtaatttatg 2550

 aaatctatgt aaacttgaaa aatatttctt aatttttgtt tttgctccag 2600

 tcaattcctg attatccaca ggtcaaccca cattttttca ttccttctcc 2650

 ctatctgctt atatcgcatt gctcatttag agtttgcagg aggctccata 2700

 ctaggttcag tctgaaagaa atctcctaat ggtgctatag agagggaggt 2750

 aacagaaaga ctcttttagg gcatttttct gactcatgaa aagagcacag 2800

 aaaaggatgt ttggcaattt gtcttttaag tcttaacctt gctaatgtga 2850

 atactgggaa agtgattttt tctcactcgt ttttgttgct ccattgtaaa 2900

 gggcggaggt cagtcttagt ggccttgaga gttgcttttg gcattaatat 2950

 tctaagagaa ttaactgtat ttcctgtcac ctattcacta gtgcaggaaa 3000

 tatacttgct ccaaataagt cagtatgaga agtcactgtc aatgaaagtt 3050

 gttttgtttg ttttcagtaa tattttgctg tttttaagac ttggaaaact 3100

 aagtgcagag tttacagagt ggtaaatatc tatgttacat gtagattata 3150

 catatatata cacacgtgta tatgagatat atatcttata tctccacaaa 3200

 cacaaattat atatatacat atccacacac atacattaca tatatctgtg 3250

 tatataaatc cacatgcaca tgaaatatat atatatatat aatttgtgtg 3300

 tgtgtatgtg tatgtatatg actttaaata gctatgggta caatattaaa 3350

 aaccactgga actcttgtcc agtttttaaa ttatgttttt actggaatgt 3400

 ttttgtgtca gtgttttctg tacatattat ttgttaattc acagctcaca 3450

 gagtgatagt tgtcatagtt cttgccttcc ctaagtttat ataaataact 3500

 taagtattgc tacagtttat ctaggttgca gtggcatctg ctgtgcacag 3550

 agcttccatg gtcactgcta agcagtagcc agccatcggg cattaattga 3600

 tttcctacta tattcccagc agacacattt agaaactaag ctatgttaac 3650

 ctcagtgctc aactatttga actgttgagt gataaaggaa acaaatataa 3700

 ctgtaaatga atcttggtat cctgtgaaac agaataattc gtaatttaag 3750

 aaagccctta tcccggtaac atgaatgttg atgaacaaat gtaaaattat 3800

 atcctatatt taagtaccca taataaatca tttccctcta taagtgttat 3850

 tgattatttt aaattgaaaa aagtttcact tggatgaaaa aagtagaaaa 3900

 gtaggtcatt cttggatcta ctttttttta gccttattaa tatttttccc 3950

 tattagaaac cacaattact ccctctatta acccttcact tactagacca 4000

 gaaaagaact tattccagat aagctttgaa tatcaattct tacataaact 4050

 ttaggcaaac agggaatagt ctagtcacca aaggaccatt ctcttgccaa 4100

 tgctgcattc cttttgcact tttggattcc atatttatcc caaatgctgt 4150

 tgggcacccc tagaaatacc ttgatgtttt ttctatttat atgcctgcct 4200

 ttggtactta attttacaaa tgctgtaata taaagcatat caagtttatg 4250

 tgatacgtat cattgcaaga gaatttgttt caagattttt ttttaatgtt 4300

 ccagaagatg gccaatagag aacattcaag ggaaatgggg aaacataatt 4350

 tagagaacaa gaacaaacca tgtctcaaat ttttttaaaa aaaattaatg 4400

 gttttaaata tatgctatag ggacgttcca tgcccaggtt aacaaagaac 4450

 tgtgatatat agagtgtcta attacaaaat catatacgat ttatttaatt 4500

 ctcttctgta ttgtaactta gatgattccc aaggactcta ataaaaaatc 4550

 acttcattgt atttggaaac aaaaacatca ttcattaatt acttattttc 4600

 tttccatagg ttttaatatt ttgagagtgt cttttttatt tcattcatga 4650

 acttttgtat ttttcatttt tcatttgatt tgtaaattta cttatgttaa 4700

 aaataaacca tttattttca gctttg 4726

<210> 5452
<211> 570
<212> PRT
<213> Homo sapien

<400> 5452
 Met Thr Leu Leu Trp Cys Val Val Ser Leu Tyr Phe Tyr Gly Ile
   1               5                  10                  15

 Leu Gln Ser Asp Ala Ser Glu Arg Cys Asp Asp Trp Gly Leu Asp
                  20                  25                  30

 Thr Met Arg Gln Ile Gln Val Phe Glu Asp Glu Pro Ala Arg Ile
                  35                  40                  45

 Lys Cys Pro Leu Phe Glu His Phe Leu Lys Phe Asn Tyr Ser Thr
                  50                  55                  60

 Ala His Ser Ala Gly Leu Thr Leu Ile Trp Tyr Trp Thr Arg Gln
                  65                  70                  75

 Asp Arg Asp Leu Glu Glu Pro Ile Asn Phe Arg Leu Pro Glu Asn
                  80                  85                  90

 Arg Ile Ser Lys Glu Lys Asp Val Leu Trp Phe Arg Pro Thr Leu
                  95                 100                 105

 Leu Asn Asp Thr Gly Asn Tyr Thr Cys Met Leu Arg Asn Thr Thr
                 110                 115                 120

 Tyr Cys Ser Lys Val Ala Phe Pro Leu Glu Val Val Gln Lys Asp
                 125                 130                 135

 Ser Cys Phe Asn Ser Pro Met Lys Leu Pro Val His Lys Leu Tyr
                 140                 145                 150

 Ile Glu Tyr Gly Ile Gln Arg Ile Thr Cys Pro Asn Val Asp Gly
                 155                 160                 165

 Tyr Phe Pro Ser Ser Val Lys Pro Thr Ile Thr Trp Tyr Met Gly
                 170                 175                 180

 Cys Tyr Lys Ile Gln Asn Phe Asn Asn Val Ile Pro Glu Gly Met
                 185                 190                 195

 Asn Leu Ser Phe Leu Ile Ala Leu Ile Ser Asn Asn Gly Asn Tyr
                 200                 205                 210

 Thr Cys Val Val Thr Tyr Pro Glu Asn Gly Arg Thr Phe His Leu
                 215                 220                 225

 Thr Arg Thr Leu Thr Val Lys Val Val Gly Ser Pro Lys Asn Ala
                 230                 235                 240

 Val Pro Pro Val Ile His Ser Pro Asn Asp His Val Val Tyr Glu
                 245                 250                 255

 Lys Glu Pro Gly Glu Glu Leu Leu Ile Pro Cys Thr Val Tyr Phe
                 260                 265                 270

 Ser Phe Leu Met Asp Ser Arg Asn Glu Val Trp Trp Thr Ile Asp
                 275                 280                 285

 Gly Lys Lys Pro Asp Asp Ile Thr Ile Asp Val Thr Ile Asn Glu
                 290                 295                 300

 Ser Ile Ser His Ser Arg Thr Glu Asp Glu Thr Arg Thr Gln Ile
                 305                 310                 315

 Leu Ser Ile Lys Lys Val Thr Ser Glu Asp Leu Lys Arg Ser Tyr
                 320                 325                 330

 Val Cys His Ala Arg Ser Ala Lys Gly Glu Val Ala Lys Ala Ala
                 335                 340                 345

 Lys Val Lys Gln Lys Val Pro Ala Pro Arg Tyr Thr Val Glu Leu
                 350                 355                 360

 Ala Cys Gly Phe Gly Ala Thr Val Leu Leu Val Val Ile Leu Ile
                 365                 370                 375

 Val Val Tyr His Val Tyr Trp Leu Glu Met Val Leu Phe Tyr Arg
                 380                 385                 390

 Ala His Phe Gly Thr Asp Glu Thr Ile Leu Asp Gly Lys Glu Tyr
                 395                 400                 405

 Asp Ile Tyr Val Ser Tyr Ala Arg Asn Ala Glu Glu Glu Glu Phe
                 410                 415                 420

 Val Leu Leu Thr Leu Arg Gly Val Leu Glu Asn Glu Phe Gly Tyr
                 425                 430                 435

 Lys Leu Cys Ile Phe Asp Arg Asp Ser Leu Pro Gly Gly Ile Val
                 440                 445                 450

 Thr Asp Glu Thr Leu Ser Phe Ile Gln Lys Ser Arg Arg Leu Leu
                 455                 460                 465

 Val Val Leu Ser Pro Asn Tyr Val Leu Gln Gly Thr Gln Ala Leu
                 470                 475                 480

 Leu Glu Leu Lys Ala Gly Leu Glu Asn Met Ala Ser Arg Gly Asn
                 485                 490                 495

 Ile Asn Val Ile Leu Val Gln Tyr Lys Ala Val Lys Glu Thr Lys
                 500                 505                 510

 Val Lys Glu Leu Lys Arg Ala Lys Thr Val Leu Thr Val Ile Lys
                 515                 520                 525

 Trp Lys Gly Glu Lys Ser Lys Tyr Pro Gln Gly Arg Phe Trp Lys
                 530                 535                 540

 Gln Leu Gln Val Ala Met Pro Val Lys Lys Ser Pro Arg Arg Ser
                 545                 550                 555

 Ser Ser Asp Glu Gln Gly Leu Ser Tyr Ser Ser Leu Lys Asn Val
                 560                 565                 570

<210> 5453
<211> 1809
<212> DNA
<213> Homo sapien

<400> 5453
 gtcttcctcc ctccctccct tcctcttact ctcattcatt tcatacacac 50

 tggctcacac atctactctc tctctctatc tctctcagaa tgacaattct 100

 aggtacaact tttggcatgg ttttttcttt acttcaagtc gtttctggag 150

 aaagtggcta tgctcaaaat ggagacttgg aagatgcaga actggatgac 200

 tactcattct catgctatag ccagttggaa gtgaatggat cgcagcactc 250

 actgacctgt gcttttgagg acccagatgt caacatcacc aatctggaat 300

 ttgaaatatg tggggccctc gtggaggtaa agtgcctgaa tttcaggaaa 350

 ctacaagaga tatatttcat cgagacaaag aaattcttac tgattggaaa 400

 gagcaatata tgtgtgaagg ttggagaaaa gagtctaacc tgcaaaaaaa 450

 tagacctaac cactatagtt aaacctgagg ctccttttga cctgagtgtc 500

 gtctatcggg aaggagccaa tgactttgtg gtgacattta atacatcaca 550

 cttgcaaaag aagtatgtaa aagttttaat gcacgatgta gcttaccgcc 600

 aggaaaagga tgaaaacaaa tggacgcatg tgaatttatc cagcacaaag 650

 ctgacactcc tgcagagaaa gctccaaccg gcagcaatgt atgagattaa 700

 agttcgatcc atccctgatc actattttaa aggcttctgg agtgaatgga 750

 gtccaagtta ttacttcaga actccagaga tcaataatag ctcaggggag 800

 atggatccta tcttactaac catcagcatt ttgagttttt tctctgtcgc 850

 tctgttggtc atcttggcct gtgtgttatg gaaaaaaagg attaagccta 900

 tcgtatggcc cagtctcccc gatcataaga agactctgga acatctttgt 950

 aagaaaccaa gaaaaaattt aaatgtgagt ttcaatcctg aaagtttcct 1000

 ggactgccag attcataggg tggatgacat tcaagctaga gatgaagtgg 1050

 aaggttttct gcaagatacg tttcctcagc aactagaaga atctgagaag 1100

 cagaggcttg gaggggatgt gcagagcccc aactgcccat ctgaggatgt 1150

 agtcatcact ccagaaagct ttggaagaga ttcatccctc acatgcctgg 1200

 ctgggaatgt cagtgcatgt gacgccccta ttctctcctc ttccaggtcc 1250

 ctagactgca gggagagtgg caagaatggg cctcatgtgt accaggacct 1300

 cctgcttagc cttgggacta caaacagcac gctgccccct ccattttctc 1350

 tccaatctgg aatcctgaca ttgaacccag ttgctcaggg tcagcccatt 1400

 cttacttccc tgggatcaaa tcaagaagaa gcatatgtca ccatgtccag 1450

 cttctaccaa aaccagtgaa gtgtaagaaa cccagactga acttaccgtg 1500

 agcgacaaag atgatttaaa agggaagtct agagttccta gtctccctca 1550

 cagcacagag aagacaaaat tagcaaaacc ccactacaca gtctgcaaga 1600

 ttctgaaaca ttgctttgac cactcttcct gagttcagtg gcactcaaca 1650

 tgagtcaaga gcatcctgct tctaccatgt ggatttggtc acaaggttta 1700

 aggtgaccca atgattcagc tatttaaaaa aaaaagagga aagaatgaaa 1750

 gagtaaagga aatgattgag gagtgaggaa ggcaggaaga gagcatgaga 1800

 ggaaaaaaa 1809

<210> 5454
<211> 459
<212> PRT
<213> Homo sapien

<400> 5454
 Met Thr Ile Leu Gly Thr Thr Phe Gly Met Val Phe Ser Leu Leu
   1               5                  10                  15

 Gln Val Val Ser Gly Glu Ser Gly Tyr Ala Gln Asn Gly Asp Leu
                  20                  25                  30

 Glu Asp Ala Glu Leu Asp Asp Tyr Ser Phe Ser Cys Tyr Ser Gln
                  35                  40                  45

 Leu Glu Val Asn Gly Ser Gln His Ser Leu Thr Cys Ala Phe Glu
                  50                  55                  60

 Asp Pro Asp Val Asn Ile Thr Asn Leu Glu Phe Glu Ile Cys Gly
                  65                  70                  75

 Ala Leu Val Glu Val Lys Cys Leu Asn Phe Arg Lys Leu Gln Glu
                  80                  85                  90

 Ile Tyr Phe Ile Glu Thr Lys Lys Phe Leu Leu Ile Gly Lys Ser
                  95                 100                 105

 Asn Ile Cys Val Lys Val Gly Glu Lys Ser Leu Thr Cys Lys Lys
                 110                 115                 120

 Ile Asp Leu Thr Thr Ile Val Lys Pro Glu Ala Pro Phe Asp Leu
                 125                 130                 135

 Ser Val Val Tyr Arg Glu Gly Ala Asn Asp Phe Val Val Thr Phe
                 140                 145                 150

 Asn Thr Ser His Leu Gln Lys Lys Tyr Val Lys Val Leu Met His
                 155                 160                 165

 Asp Val Ala Tyr Arg Gln Glu Lys Asp Glu Asn Lys Trp Thr His
                 170                 175                 180

 Val Asn Leu Ser Ser Thr Lys Leu Thr Leu Leu Gln Arg Lys Leu
                 185                 190                 195

 Gln Pro Ala Ala Met Tyr Glu Ile Lys Val Arg Ser Ile Pro Asp
                 200                 205                 210

 His Tyr Phe Lys Gly Phe Trp Ser Glu Trp Ser Pro Ser Tyr Tyr
                 215                 220                 225

 Phe Arg Thr Pro Glu Ile Asn Asn Ser Ser Gly Glu Met Asp Pro
                 230                 235                 240

 Ile Leu Leu Thr Ile Ser Ile Leu Ser Phe Phe Ser Val Ala Leu
                 245                 250                 255

 Leu Val Ile Leu Ala Cys Val Leu Trp Lys Lys Arg Ile Lys Pro
                 260                 265                 270

 Ile Val Trp Pro Ser Leu Pro Asp His Lys Lys Thr Leu Glu His
                 275                 280                 285

 Leu Cys Lys Lys Pro Arg Lys Asn Leu Asn Val Ser Phe Asn Pro
                 290                 295                 300

 Glu Ser Phe Leu Asp Cys Gln Ile His Arg Val Asp Asp Ile Gln
                 305                 310                 315

 Ala Arg Asp Glu Val Glu Gly Phe Leu Gln Asp Thr Phe Pro Gln
                 320                 325                 330

 Gln Leu Glu Glu Ser Glu Lys Gln Arg Leu Gly Gly Asp Val Gln
                 335                 340                 345

 Ser Pro Asn Cys Pro Ser Glu Asp Val Val Ile Thr Pro Glu Ser
                 350                 355                 360

 Phe Gly Arg Asp Ser Ser Leu Thr Cys Leu Ala Gly Asn Val Ser
                 365                 370                 375

 Ala Cys Asp Ala Pro Ile Leu Ser Ser Ser Arg Ser Leu Asp Cys
                 380                 385                 390

 Arg Glu Ser Gly Lys Asn Gly Pro His Val Tyr Gln Asp Leu Leu
                 395                 400                 405

 Leu Ser Leu Gly Thr Thr Asn Ser Thr Leu Pro Pro Pro Phe Ser
                 410                 415                 420

 Leu Gln Ser Gly Ile Leu Thr Leu Asn Pro Val Ala Gln Gly Gln
                 425                 430                 435

 Pro Ile Leu Thr Ser Leu Gly Ser Asn Gln Glu Glu Ala Tyr Val
                 440                 445                 450

 Thr Met Ser Ser Phe Tyr Gln Asn Gln
                 455

<210> 5455
<211> 2171
<212> DNA
<213> Homo sapien

<400> 5455
 agcagctctg taatgcgctt gtggtttcag atgtgggcgg cctgtgtgaa 50

 cctgtcgtgc aaagctcacg tcaccaactg ctgcagttat ctcctgaatc 100

 aggctgaggg tctttgctgt gcacccagag atagttgggt gacaaatcac 150

 ctccaggttg gggatgcctc agacttgtga tgggactggg cagatgcatc 200

 tgggaaggct ggaccttgga gagtgaggcc ctgaggcgag acatgggcac 250

 ctggctcctg gcctgcatct gcatctgcac ctgtgtctgc ttgggagtct 300

 ctgtcacagg ggaaggacaa gggccaaggt ctagaacctt cacctgcctc 350

 accaacaaca ttctcaggat cgattgccac tggtctgccc cagagctggg 400

 acagggctcc agcccctggc tcctcttcac cagcaaccag gctcctggcg 450

 gcacacataa gtgcatcttg cggggcagtg agtgcaccgt cgtgctgcca 500

 cctgaggcag tgctcgtgcc atctgacaat ttcaccatca ctttccacca 550

 ctgcatgtct gggagggagc aggtcagcct ggtggacccg gagtacctgc 600

 cccggagaca cgttaagctg gacccgccct ctgacttgca gagcaacatc 650

 agttctggcc actgcatcct gacctggagc atcagtcctg ccttggagcc 700

 aatgaccaca cttctcagct atgagctggc cttcaagaag caggaagagg 750

 cctgggagca ggcccagcac agggatcaca ttgtcggggt gacctggctt 800

 atacttgaag cctttgagct ggaccctggc tttatccatg aggccaggct 850

 gcgtgtccag atggccacac tggaggatga tgtggtagag gaggagcgtt 900

 atacaggcca gtggagtgag tggagccagc ctgtgtgctt ccaggctccc 950

 cagagacaag gccctctgat cccaccctgg gggtggccag gcaacaccct 1000

 tgttgctgtg tccatctttc tcctgctgac tggcccgacc tacctcctgt 1050

 tcaagctgtc gcccagggtg aagagaatct tctaccagaa cgtgccctct 1100

 ccagcgatgt tcttccagcc cctctacagt gtacacaatg ggaacttcca 1150

 gacttggatg ggggcccacg gggccggtgt gctgttgagc caggactgtg 1200

 ctggcacccc acagggagcc ttggagccct gcgtccagga ggccactgca 1250

 ctgctcactt gtggcccagc gcgtccttgg aaatctgtgg ccctggagga 1300

 ggaacaggag ggccctggga ccaggctccc ggggaacctg agctcagagg 1350

 atgtgctgcc agcagggtgt acggagtgga gggtacagac gcttgcctat 1400

 ctgccacagg aggactgggc ccccacgtcc ctgactaggc cggctccccc 1450

 agactcagag ggcagcagga gcagcagcag cagcagcagc agcaacaaca 1500

 acaactactg tgccttgggc tgctatgggg gatggcacct ctcagccctc 1550

 ccaggaaaca cacagagctc tgggcccatc ccagccctgg cctgtggcct 1600

 ttcttgtgac catcagggcc tggagaccca gcaaggagtt gcctgggtgc 1650

 tggctggtca ctgccagagg cctgggctgc atgaggacct ccagggcatg 1700

 ttgctccctt ctgtcctcag caaggctcgg tcctggacat tctaggtccc 1750

 tgactcgcca gatgcatcat gtccattttg ggaaaatgga ctgaagtttc 1800

 tggagccctt gtctgagact gaacctcctg agaaggggcc cctagcagcg 1850

 gtcagaggtc ctgtctggat ggaggctgga ggctcccccc tcaacccctc 1900

 tgctcagtgc ctgtggggag cagcctctac cctcagcatc ctggccacaa 1950

 gttcttcctt ccattgtccc ttttctttat ccctgacctc tctgagaagt 2000

 ggggtgtggt ctctcagctg ttctgccctc atacccttaa agggccagcc 2050

 tgggcccagt ggacacaggt aaggcaccat gaccacctgg tgtgacctct 2100

 ctgtgcctta ctgaggcacc tttctagaga ttaaaagggg cttgatggct 2150

 gttaaaaaaa aaaaaaaaaa a 2171

<210> 5456
<211> 521
<212> PRT
<213> Homo sapien

<400> 5456
 Met Gly Leu Gly Arg Cys Ile Trp Glu Gly Trp Thr Leu Glu Ser
   1               5                  10                  15

 Glu Ala Leu Arg Arg Asp Met Gly Thr Trp Leu Leu Ala Cys Ile
                  20                  25                  30

 Cys Ile Cys Thr Cys Val Cys Leu Gly Val Ser Val Thr Gly Glu
                  35                  40                  45

 Gly Gln Gly Pro Arg Ser Arg Thr Phe Thr Cys Leu Thr Asn Asn
                  50                  55                  60

 Ile Leu Arg Ile Asp Cys His Trp Ser Ala Pro Glu Leu Gly Gln
                  65                  70                  75

 Gly Ser Ser Pro Trp Leu Leu Phe Thr Ser Asn Gln Ala Pro Gly
                  80                  85                  90

 Gly Thr His Lys Cys Ile Leu Arg Gly Ser Glu Cys Thr Val Val
                  95                 100                 105

 Leu Pro Pro Glu Ala Val Leu Val Pro Ser Asp Asn Phe Thr Ile
                 110                 115                 120

 Thr Phe His His Cys Met Ser Gly Arg Glu Gln Val Ser Leu Val
                 125                 130                 135

 Asp Pro Glu Tyr Leu Pro Arg Arg His Val Lys Leu Asp Pro Pro
                 140                 145                 150

 Ser Asp Leu Gln Ser Asn Ile Ser Ser Gly His Cys Ile Leu Thr
                 155                 160                 165

 Trp Ser Ile Ser Pro Ala Leu Glu Pro Met Thr Thr Leu Leu Ser
                 170                 175                 180

 Tyr Glu Leu Ala Phe Lys Lys Gln Glu Glu Ala Trp Glu Gln Ala
                 185                 190                 195

 Gln His Arg Asp His Ile Val Gly Val Thr Trp Leu Ile Leu Glu
                 200                 205                 210

 Ala Phe Glu Leu Asp Pro Gly Phe Ile His Glu Ala Arg Leu Arg
                 215                 220                 225

 Val Gln Met Ala Thr Leu Glu Asp Asp Val Val Glu Glu Glu Arg
                 230                 235                 240

 Tyr Thr Gly Gln Trp Ser Glu Trp Ser Gln Pro Val Cys Phe Gln
                 245                 250                 255

 Ala Pro Gln Arg Gln Gly Pro Leu Ile Pro Pro Trp Gly Trp Pro
                 260                 265                 270

 Gly Asn Thr Leu Val Ala Val Ser Ile Phe Leu Leu Leu Thr Gly
                 275                 280                 285

 Pro Thr Tyr Leu Leu Phe Lys Leu Ser Pro Arg Val Lys Arg Ile
                 290                 295                 300

 Phe Tyr Gln Asn Val Pro Ser Pro Ala Met Phe Phe Gln Pro Leu
                 305                 310                 315

 Tyr Ser Val His Asn Gly Asn Phe Gln Thr Trp Met Gly Ala His
                 320                 325                 330

 Gly Ala Gly Val Leu Leu Ser Gln Asp Cys Ala Gly Thr Pro Gln
                 335                 340                 345

 Gly Ala Leu Glu Pro Cys Val Gln Glu Ala Thr Ala Leu Leu Thr
                 350                 355                 360

 Cys Gly Pro Ala Arg Pro Trp Lys Ser Val Ala Leu Glu Glu Glu
                 365                 370                 375

 Gln Glu Gly Pro Gly Thr Arg Leu Pro Gly Asn Leu Ser Ser Glu
                 380                 385                 390

 Asp Val Leu Pro Ala Gly Cys Thr Glu Trp Arg Val Gln Thr Leu
                 395                 400                 405

 Ala Tyr Leu Pro Gln Glu Asp Trp Ala Pro Thr Ser Leu Thr Arg
                 410                 415                 420

 Pro Ala Pro Pro Asp Ser Glu Gly Ser Arg Ser Ser Ser Ser Ser
                 425                 430                 435

 Ser Ser Ser Asn Asn Asn Asn Tyr Cys Ala Leu Gly Cys Tyr Gly
                 440                 445                 450

 Gly Trp His Leu Ser Ala Leu Pro Gly Asn Thr Gln Ser Ser Gly
                 455                 460                 465

 Pro Ile Pro Ala Leu Ala Cys Gly Leu Ser Cys Asp His Gln Gly
                 470                 475                 480

 Leu Glu Thr Gln Gln Gly Val Ala Trp Val Leu Ala Gly His Cys
                 485                 490                 495

 Gln Arg Pro Gly Leu His Glu Asp Leu Gln Gly Met Leu Leu Pro
                 500                 505                 510

 Ser Val Leu Ser Lys Ala Arg Ser Trp Thr Phe
                 515                 520

<210> 5457
<211> 1282
<212> DNA
<213> Homo sapien

<400> 5457
 aagccaccca gcctatgcat ccgctcctca atcctctcct gttggcactg 50

 ggcctcatgg cgcttttgtt gaccacggtc attgctctca cttgccttgg 100

 cggctttgcc tccccaggcc ctgtgcctcc ctctacagcc ctcagggagc 150

 tcattgagga gctggtcaac atcacccaga accagaaggc tccgctctgc 200

 aatggcagca tggtatggag catcaacctg acagctggca tgtactgtgc 250

 agccctggaa tccctgatca acgtgtcagg ctgcagtgcc atcgagaaga 300

 cccagaggat gctgagcgga ttctgcccgc acaaggtctc agctgggcag 350

 ttttccagct tgcatgtccg agacaccaaa atcgaggtgg cccagtttgt 400

 aaaggacctg ctcttacatt taaagaaact ttttcgcgag ggacagttca 450

 actgaaactt cgaaagcatc attatttgca gagacaggac ctgactattg 500

 aagttgcaga ttcatttttc tttctgatgt caaaaatgtc ttgggtaggc 550

 gggaaggagg gttagggagg ggtaaaattc cttagcttag acctcagcct 600

 gtgctgcccg tcttcagcct agccgacctc agccttcccc ttgcccaggg 650

 ctcagcctgg tgggcctcct ctgtccaggg ccctgagctc ggtggaccca 700

 gggatgacat gtccctacac ccctcccctg ccctagagca cactgtagca 750

 ttacagtggg tgcccccctt gccagacatg tggtgggaca gggacccact 800

 tcacacacag gcaactgagg cagacagcag ctcaggcaca cttcttcttg 850

 gtcttattta ttattgtgtg ttatttaaat gagtgtgttt gtcaccgttg 900

 gggattgggg aagactgtgg ctgctagcac ttggagccaa gggttcagag 950

 actcagggcc ccagcactaa agcagtggac accaggagtc cctggtaata 1000

 agtactgtgt acagaattct gctacctcac tggggtcctg gggcctcgga 1050

 gcctcatccg aggcagggtc aggagagggg cagaacagcc gctcctgtct 1100

 gccagccagc agccagctct cagccaacga gtaatttatt gtttttcctt 1150

 gtatttaaat attaaatatg ttagcaaaga gttaatatat agaagggtac 1200

 cttgaacact gggggagggg acattgaaca agttgtttca ttgactatca 1250

 aactgaagcc agaaataaag ttggtgacag at 1282

<210> 5458
<211> 146
<212> PRT
<213> Homo sapien

<400> 5458
 Met His Pro Leu Leu Asn Pro Leu Leu Leu Ala Leu Gly Leu Met
   1               5                  10                  15

 Ala Leu Leu Leu Thr Thr Val Ile Ala Leu Thr Cys Leu Gly Gly
                  20                  25                  30

 Phe Ala Ser Pro Gly Pro Val Pro Pro Ser Thr Ala Leu Arg Glu
                  35                  40                  45

 Leu Ile Glu Glu Leu Val Asn Ile Thr Gln Asn Gln Lys Ala Pro
                  50                  55                  60

 Leu Cys Asn Gly Ser Met Val Trp Ser Ile Asn Leu Thr Ala Gly
                  65                  70                  75

 Met Tyr Cys Ala Ala Leu Glu Ser Leu Ile Asn Val Ser Gly Cys
                  80                  85                  90

 Ser Ala Ile Glu Lys Thr Gln Arg Met Leu Ser Gly Phe Cys Pro
                  95                 100                 105

 His Lys Val Ser Ala Gly Gln Phe Ser Ser Leu His Val Arg Asp
                 110                 115                 120

 Thr Lys Ile Glu Val Ala Gln Phe Val Lys Asp Leu Leu Leu His
                 125                 130                 135

 Leu Lys Lys Leu Phe Arg Glu Gly Gln Phe Asn
                 140                 145

<210> 5459
<211> 5361
<212> DNA
<213> Homo sapien

<400> 5459
 ctgcaaaccc agcgcaacta cggtcccccg gtcagaccca ggatggggcc 50

 agaacggaca ggggccgcgc cgctgccgct gctgctggtg ttagcgctca 100

 gtcaaggcat tttaaattgt tgtttggcct acaatgttgg tctcccagaa 150

 gcaaaaatat tttccggtcc ttcaagtgaa cagtttgggt atgcagtgca 200

 gcagtttata aatccaaaag gcaactggtt actggttggt tcaccctgga 250

 gtggctttcc tgagaaccga atgggagatg tgtataaatg tcctgttgac 300

 ctatccactg ccacatgtga aaaactaaat ttgcaaactt caacaagcat 350

 tccaaatgtt actgagatga aaaccaacat gagcctcggc ttgatcctca 400

 ccaggaacat gggaactgga ggttttctca catgtggtcc tctgtgggca 450

 cagcaatgtg ggaatcagta ttacacaacg ggtgtgtgtt ctgacatcag 500

 tcctgatttt cagctctcag ccagcttctc acctgcaact cagccctgcc 550

 cttccctcat agatgttgtg gttgtgtgtg atgaatcaaa tagtatttat 600

 ccttgggatg cagtaaagaa ttttttggaa aaatttgtac aaggccttga 650

 tataggcccc acaaagacac aggtggggtt aattcagtat gccaataatc 700

 caagagttgt gtttaacttg aacacatata aaaccaaaga agaaatgatt 750

 gtagcaacat cccagacatc ccaatatggt ggggacctca caaacacatt 800

 cggagcaatt caatatgcaa gaaaatatgc ctattcagca gcttctggtg 850

 ggcgacgaag tgctacgaaa gtaatggtag ttgtaactga cggtgaatca 900

 catgatggtt caatgttgaa agctgtgatt gatcaatgca accatgacaa 950

 tatactgagg tttggcatag cagttcttgg gtacttaaac agaaacgccc 1000

 ttgatactaa aaatttaata aaagaaataa aagcgatcgc tagtattcca 1050

 acagaaagat actttttcaa tgtgtctgat gaagcagctc tactagaaaa 1100

 ggctgggaca ttaggagaac aaattttcag cattgaaggt actgttcaag 1150

 gaggagacaa ctttcagatg gaaatgtcac aagtgggatt cagtgcagat 1200

 tactcttctc aaaatgatat tctgatgctg ggtgcagtgg gagcttttgg 1250

 ctggagtggg accattgtcc agaagacatc tcatggccat ttgatctttc 1300

 ctaaacaagc ctttgaccaa attctgcagg acagaaatca cagttcatat 1350

 ttaggttact ctgtggctgc aatttctact ggagaaagca ctcactttgt 1400

 tgctggtgct cctcgggcaa attataccgg ccagatagtg ctatatagtg 1450

 tgaatgagaa tggcaatatc acggttattc aggctcaccg aggtgaccag 1500

 attggctcct attttggtag tgtgctgtgt tcagttgatg tggataaaga 1550

 caccattaca gacgtgctct tggtaggtgc accaatgtac atgagtgacc 1600

 taaagaaaga ggaaggaaga gtctacctgt ttactatcaa aaagggcatt 1650

 ttgggtcagc accaatttct tgaaggcccc gagggcattg aaaacactcg 1700

 atttggttca gcaattgcag ctctttcaga catcaacatg gatggcttta 1750

 atgatgtgat tgttggttca ccactagaaa atcagaattc tggagctgta 1800

 tacatttaca atggtcatca gggcactatc cgcacaaagt attcccagaa 1850

 aatcttggga tccgatggag cctttaggag ccatctccag tactttggga 1900

 ggtccttgga tggctatgga gatttaaatg gggattccat caccgatgtg 1950

 tctattggtg cctttggaca agtggttcaa ctctggtcac aaagtattgc 2000

 tgatgtagct atagaagctt cattcacacc agaaaaaatc actttggtca 2050

 acaagaatgc tcagataatt ctcaaactct gcttcagtgc aaagttcaga 2100

 cctactaagc aaaacaatca agtggccatt gtatataaca tcacacttga 2150

 tgcagatgga ttttcatcca gagtaacctc cagggggtta tttaaagaaa 2200

 acaatgaaag gtgcctgcag aagaatatgg tagtaaatca agcacagagt 2250

 tgccccgagc acatcattta tatacaggag ccctctgatg ttgtcaactc 2300

 tttggatttg cgtgtggaca tcagtctgga aaaccctggc actagccctg 2350

 cccttgaagc ctattctgag actgccaagg tcttcagtat tcctttccac 2400

 aaagactgtg gtgaggatgg actttgcatt tctgatctag tcctagatgt 2450

 ccgacaaata ccagctgctc aagaacaacc ctttattgtc agcaaccaaa 2500

 acaaaaggtt aacattttca gtaacactga aaaataaaag ggaaagtgca 2550

 tacaacactg gaattgttgt tgatttttca gaaaacttgt tttttgcatc 2600

 attctcccta ccggttgatg ggacagaagt aacatgccag gtggctgcat 2650

 ctcagaagtc tgttgcctgc gatgtaggct accctgcttt aaagagagaa 2700

 caacaggtga cttttactat taactttgac ttcaatcttc aaaaccttca 2750

 gaatcaggcg tctctcagtt tccaagcctt aagtgaaagc caagaagaaa 2800

 acaaggctga taatttggtc aacctcaaaa ttcctctcct gtatgatgct 2850

 gaaattcact taacaagatc taccaacata aatttttatg aaatctcttc 2900

 ggatgggaat gttccttcaa tcgtgcacag ttttgaagat gttggtccaa 2950

 aattcatctt ctccctgaag gtaacaacag gaagtgttcc agtaagcatg 3000

 gcaactgtaa tcatccacat ccctcagtat accaaagaaa agaacccact 3050

 gatgtaccta actggggtgc aaacagacaa ggctggtgac atcagttgta 3100

 atgcagatat caatccactg aaaataggac aaacatcttc ttctgtatct 3150

 ttcaaaagtg aaaatttcag gcacaccaaa gaattgaact gcagaactgc 3200

 ttcctgtagt aatgttacct gctggttgaa agacgttcac atgaaaggag 3250

 aatactttgt taatgtgact accagaattt ggaacgggac tttcgcatca 3300

 tcaacgttcc agacagtaca gctaacggca gctgcagaaa tcaacaccta 3350

 taaccctgag atatatgtga ttgaagataa cactgttacg attcccctga 3400

 tgataatgaa acctgatgag aaagccgaag taccaacagg agttataata 3450

 ggaagtataa ttgctggaat ccttttgctg ttagctctgg ttgcaatttt 3500

 atggaagctc ggcttcttca aaagaaaata tgaaaagatg accaaaaatc 3550

 cagatgagat tgatgagacc acagagctca gtagctgaac cagcagacct 3600

 acctgcagtg ggaaccggca gcatcccagc cagggtttgc tgtttgcgtg 3650

 catggatttc tttttaaatc ccatattttt tttatcatgt cgtaggtaaa 3700

 ctaacctggt attttaagag aaaactgcag gtcagtttgg atgaagaaat 3750

 tgtggggggt gggggaggtg cggggggcag gtagggaaat aatagggaaa 3800

 atacctattt tatatgatgg gggaaaaaaa gtaatcttta aactggctgg 3850

 cccagagttt acattctaat ttgcattgtg tcagaaacat gaaatgcttc 3900

 caagcatgac aacttttaaa gaaaaatatg atactctcag attttaaggg 3950

 ggaaaactgt tctctttaaa atatttgtct ttaaacagca actacagaag 4000

 tggaagtgct tgatatgtaa gtacttccac ttgtgtatat tttaatgaat 4050

 attgatgtta acaagagggg aaaacaaaac acaggttttt tcaatttatg 4100

 ctgctcatcc aaagttgcca cagatgatac ttccaagtga taattttatt 4150

 tataaactag gtaaaatttg ttgttggttc cttttatacc acggctgccc 4200

 cttccacacc ccatcttgct ctaatgatca aaacatgctt gaataactga 4250

 gcttagagta tacctcctat atgtccattt aagttaggag agggggcgat 4300

 atagagacta aggcacaaaa ttttgtttaa aactcagaat ataacattta 4350

 tgtaaaatcc catctgctag aagcccatcc tgtgccagag gaaggaaaag 4400

 gaggaaattt cctttctctt ttaggaggca caacagttct cttctaggat 4450

 ttgtttggct gactggcagt aacctagtga atttttgaaa gatgagtaat 4500

 ttctttggca accttcctcc tcccttactg aaccactctc ccacctcctg 4550

 gtggtaccat tattatagaa gccctctaca gcctgacttt ctctccagcg 4600

 gtccaaagtt atcccctcct ttacccctca tccaaagttc ccactccttc 4650

 aggacagctg ctgtgcatta gatattaggg gggaaagtca tctgtttaat 4700

 ttacacactt gcatgaatta ctgtatataa actccttaac ttcagggagc 4750

 tattttcatt tagtgctaaa caagtaagaa aaataagcta gagtgaattt 4800

 ctaaatgttg gaatgttatg ggatgtaaac aatgtaaagt aaaacactct 4850

 caggatttca ccagaagtta cagatgaggc actggaaacc accaccaaat 4900

 tagcaggtgc accttctgtg gctgtcttgt ttctgaagta ctttttcttc 4950

 cacaagagtg aatttgacct aggcaagttt gttcaaaagg tagatcctga 5000

 gatgatttgg tcagattggg ataaggccca gcaatctgca ttttaacaag 5050

 caccccagtc actaggatgc agatggacca cactttgaga aacaccaccc 5100

 atttctactt tttgcacctt attttctctg ttcctgagcc cccacattct 5150

 ctaggagaaa cttagattaa aattcacaga cactacatat ctaaagcttt 5200

 gacaagtcct tgacctctat aaacttcaga gtcctcatta taaaatggga 5250

 agactgagct ggagttcagc agtgatgctt tttagtttta aaagtctatg 5300

 atctgatctg gacttcctat aatacaaata cacaatcctc caagaatttg 5350

 acttggaaaa g 5361

<210> 5460
<211> 1181
<212> PRT
<213> Homo sapien

<400> 5460
 Met Gly Pro Glu Arg Thr Gly Ala Ala Pro Leu Pro Leu Leu Leu
   1               5                  10                  15

 Val Leu Ala Leu Ser Gln Gly Ile Leu Asn Cys Cys Leu Ala Tyr
                  20                  25                  30

 Asn Val Gly Leu Pro Glu Ala Lys Ile Phe Ser Gly Pro Ser Ser
                  35                  40                  45

 Glu Gln Phe Gly Tyr Ala Val Gln Gln Phe Ile Asn Pro Lys Gly
                  50                  55                  60

 Asn Trp Leu Leu Val Gly Ser Pro Trp Ser Gly Phe Pro Glu Asn
                  65                  70                  75

 Arg Met Gly Asp Val Tyr Lys Cys Pro Val Asp Leu Ser Thr Ala
                  80                  85                  90

 Thr Cys Glu Lys Leu Asn Leu Gln Thr Ser Thr Ser Ile Pro Asn
                  95                 100                 105

 Val Thr Glu Met Lys Thr Asn Met Ser Leu Gly Leu Ile Leu Thr
                 110                 115                 120

 Arg Asn Met Gly Thr Gly Gly Phe Leu Thr Cys Gly Pro Leu Trp
                 125                 130                 135

 Ala Gln Gln Cys Gly Asn Gln Tyr Tyr Thr Thr Gly Val Cys Ser
                 140                 145                 150

 Asp Ile Ser Pro Asp Phe Gln Leu Ser Ala Ser Phe Ser Pro Ala
                 155                 160                 165

 Thr Gln Pro Cys Pro Ser Leu Ile Asp Val Val Val Val Cys Asp
                 170                 175                 180

 Glu Ser Asn Ser Ile Tyr Pro Trp Asp Ala Val Lys Asn Phe Leu
                 185                 190                 195

 Glu Lys Phe Val Gln Gly Leu Asp Ile Gly Pro Thr Lys Thr Gln
                 200                 205                 210

 Val Gly Leu Ile Gln Tyr Ala Asn Asn Pro Arg Val Val Phe Asn
                 215                 220                 225

 Leu Asn Thr Tyr Lys Thr Lys Glu Glu Met Ile Val Ala Thr Ser
                 230                 235                 240

 Gln Thr Ser Gln Tyr Gly Gly Asp Leu Thr Asn Thr Phe Gly Ala
                 245                 250                 255

 Ile Gln Tyr Ala Arg Lys Tyr Ala Tyr Ser Ala Ala Ser Gly Gly
                 260                 265                 270

 Arg Arg Ser Ala Thr Lys Val Met Val Val Val Thr Asp Gly Glu
                 275                 280                 285

 Ser His Asp Gly Ser Met Leu Lys Ala Val Ile Asp Gln Cys Asn
                 290                 295                 300

 His Asp Asn Ile Leu Arg Phe Gly Ile Ala Val Leu Gly Tyr Leu
                 305                 310                 315

 Asn Arg Asn Ala Leu Asp Thr Lys Asn Leu Ile Lys Glu Ile Lys
                 320                 325                 330

 Ala Ile Ala Ser Ile Pro Thr Glu Arg Tyr Phe Phe Asn Val Ser
                 335                 340                 345

 Asp Glu Ala Ala Leu Leu Glu Lys Ala Gly Thr Leu Gly Glu Gln
                 350                 355                 360

 Ile Phe Ser Ile Glu Gly Thr Val Gln Gly Gly Asp Asn Phe Gln
                 365                 370                 375

 Met Glu Met Ser Gln Val Gly Phe Ser Ala Asp Tyr Ser Ser Gln
                 380                 385                 390

 Asn Asp Ile Leu Met Leu Gly Ala Val Gly Ala Phe Gly Trp Ser
                 395                 400                 405

 Gly Thr Ile Val Gln Lys Thr Ser His Gly His Leu Ile Phe Pro
                 410                 415                 420

 Lys Gln Ala Phe Asp Gln Ile Leu Gln Asp Arg Asn His Ser Ser
                 425                 430                 435

 Tyr Leu Gly Tyr Ser Val Ala Ala Ile Ser Thr Gly Glu Ser Thr
                 440                 445                 450

 His Phe Val Ala Gly Ala Pro Arg Ala Asn Tyr Thr Gly Gln Ile
                 455                 460                 465

 Val Leu Tyr Ser Val Asn Glu Asn Gly Asn Ile Thr Val Ile Gln
                 470                 475                 480

 Ala His Arg Gly Asp Gln Ile Gly Ser Tyr Phe Gly Ser Val Leu
                 485                 490                 495

 Cys Ser Val Asp Val Asp Lys Asp Thr Ile Thr Asp Val Leu Leu
                 500                 505                 510

 Val Gly Ala Pro Met Tyr Met Ser Asp Leu Lys Lys Glu Glu Gly
                 515                 520                 525

 Arg Val Tyr Leu Phe Thr Ile Lys Lys Gly Ile Leu Gly Gln His
                 530                 535                 540

 Gln Phe Leu Glu Gly Pro Glu Gly Ile Glu Asn Thr Arg Phe Gly
                 545                 550                 555

 Ser Ala Ile Ala Ala Leu Ser Asp Ile Asn Met Asp Gly Phe Asn
                 560                 565                 570

 Asp Val Ile Val Gly Ser Pro Leu Glu Asn Gln Asn Ser Gly Ala
                 575                 580                 585

 Val Tyr Ile Tyr Asn Gly His Gln Gly Thr Ile Arg Thr Lys Tyr
                 590                 595                 600

 Ser Gln Lys Ile Leu Gly Ser Asp Gly Ala Phe Arg Ser His Leu
                 605                 610                 615

 Gln Tyr Phe Gly Arg Ser Leu Asp Gly Tyr Gly Asp Leu Asn Gly
                 620                 625                 630

 Asp Ser Ile Thr Asp Val Ser Ile Gly Ala Phe Gly Gln Val Val
                 635                 640                 645

 Gln Leu Trp Ser Gln Ser Ile Ala Asp Val Ala Ile Glu Ala Ser
                 650                 655                 660

 Phe Thr Pro Glu Lys Ile Thr Leu Val Asn Lys Asn Ala Gln Ile
                 665                 670                 675

 Ile Leu Lys Leu Cys Phe Ser Ala Lys Phe Arg Pro Thr Lys Gln
                 680                 685                 690

 Asn Asn Gln Val Ala Ile Val Tyr Asn Ile Thr Leu Asp Ala Asp
                 695                 700                 705

 Gly Phe Ser Ser Arg Val Thr Ser Arg Gly Leu Phe Lys Glu Asn
                 710                 715                 720

 Asn Glu Arg Cys Leu Gln Lys Asn Met Val Val Asn Gln Ala Gln
                 725                 730                 735

 Ser Cys Pro Glu His Ile Ile Tyr Ile Gln Glu Pro Ser Asp Val
                 740                 745                 750

 Val Asn Ser Leu Asp Leu Arg Val Asp Ile Ser Leu Glu Asn Pro
                 755                 760                 765

 Gly Thr Ser Pro Ala Leu Glu Ala Tyr Ser Glu Thr Ala Lys Val
                 770                 775                 780

 Phe Ser Ile Pro Phe His Lys Asp Cys Gly Glu Asp Gly Leu Cys
                 785                 790                 795

 Ile Ser Asp Leu Val Leu Asp Val Arg Gln Ile Pro Ala Ala Gln
                 800                 805                 810

 Glu Gln Pro Phe Ile Val Ser Asn Gln Asn Lys Arg Leu Thr Phe
                 815                 820                 825

 Ser Val Thr Leu Lys Asn Lys Arg Glu Ser Ala Tyr Asn Thr Gly
                 830                 835                 840

 Ile Val Val Asp Phe Ser Glu Asn Leu Phe Phe Ala Ser Phe Ser
                 845                 850                 855

 Leu Pro Val Asp Gly Thr Glu Val Thr Cys Gln Val Ala Ala Ser
                 860                 865                 870

 Gln Lys Ser Val Ala Cys Asp Val Gly Tyr Pro Ala Leu Lys Arg
                 875                 880                 885

 Glu Gln Gln Val Thr Phe Thr Ile Asn Phe Asp Phe Asn Leu Gln
                 890                 895                 900

 Asn Leu Gln Asn Gln Ala Ser Leu Ser Phe Gln Ala Leu Ser Glu
                 905                 910                 915

 Ser Gln Glu Glu Asn Lys Ala Asp Asn Leu Val Asn Leu Lys Ile
                 920                 925                 930

 Pro Leu Leu Tyr Asp Ala Glu Ile His Leu Thr Arg Ser Thr Asn
                 935                 940                 945

 Ile Asn Phe Tyr Glu Ile Ser Ser Asp Gly Asn Val Pro Ser Ile
                 950                 955                 960

 Val His Ser Phe Glu Asp Val Gly Pro Lys Phe Ile Phe Ser Leu
                 965                 970                 975

 Lys Val Thr Thr Gly Ser Val Pro Val Ser Met Ala Thr Val Ile
                 980                 985                 990

 Ile His Ile Pro Gln Tyr Thr Lys Glu Lys Asn Pro Leu Met Tyr
                 995                1000                1005

 Leu Thr Gly Val Gln Thr Asp Lys Ala Gly Asp Ile Ser Cys Asn
                1010                1015                1020

 Ala Asp Ile Asn Pro Leu Lys Ile Gly Gln Thr Ser Ser Ser Val
                1025                1030                1035

 Ser Phe Lys Ser Glu Asn Phe Arg His Thr Lys Glu Leu Asn Cys
                1040                1045                1050

 Arg Thr Ala Ser Cys Ser Asn Val Thr Cys Trp Leu Lys Asp Val
                1055                1060                1065

 His Met Lys Gly Glu Tyr Phe Val Asn Val Thr Thr Arg Ile Trp
                1070                1075                1080

 Asn Gly Thr Phe Ala Ser Ser Thr Phe Gln Thr Val Gln Leu Thr
                1085                1090                1095

 Ala Ala Ala Glu Ile Asn Thr Tyr Asn Pro Glu Ile Tyr Val Ile
                1100                1105                1110

 Glu Asp Asn Thr Val Thr Ile Pro Leu Met Ile Met Lys Pro Asp
                1115                1120                1125

 Glu Lys Ala Glu Val Pro Thr Gly Val Ile Ile Gly Ser Ile Ile
                1130                1135                1140

 Ala Gly Ile Leu Leu Leu Leu Ala Leu Val Ala Ile Leu Trp Lys
                1145                1150                1155

 Leu Gly Phe Phe Lys Arg Lys Tyr Glu Lys Met Thr Lys Asn Pro
                1160                1165                1170

 Asp Glu Ile Asp Glu Thr Thr Glu Leu Ser Ser
                1175                1180

<210> 5461
<211> 5133
<212> DNA
<213> Homo sapien

<400> 5461
 cctctttcac cctgtctagg ttgccagcaa atcccacggg cctcctgacg 50

 ctgcccctgg ggccacaggt ccctcgagtg ctggaaggat gaaggattcc 100

 tgcatcactg tgatggccat ggcgctgctg tctgggttct ttttcttcgc 150

 gccggcctcg agctacaacc tggacgtgcg gggcgcgcgg agcttctccc 200

 caccgcgcgc cgggaggcac tttggatacc gcgtcctgca ggtcggaaac 250

 ggggtcatcg tgggagctcc aggggagggg aacagcacag gaagcctcta 300

 tcagtgccag tcgggcacag gacactgcct gccagtcacc ctgagaggtt 350

 ccaactatac ctccaagtac ttgggaatga ccttggcaac agaccccaca 400

 gatggaagca ttttggcctg tgaccctggg ctgtctcgaa cgtgtgacca 450

 gaacacctat ctgagtggcc tgtgttacct cttccgccag aatctgcagg 500

 gtcccatgct gcaggggcgc cctggttttc aggaatgtat caagggcaac 550

 gtagacctgg tatttctgtt tgatggttcg atgagcttgc agccagatga 600

 atttcagaaa attctggact tcatgaagga tgtgatgaag aaactcagca 650

 acacttcgta ccagtttgct gctgttcagt tttccacaag ctacaaaaca 700

 gaatttgatt tctcagatta tgttaaatgg aaggaccctg atgctctgct 750

 gaagcatgta aagcacatgt tgctgttgac caataccttt ggtgccatca 800

 attatgtcgc gacagaggtg ttccgggagg agctgggggc ccggccagat 850

 gccaccaaag tgcttatcat catcacggat ggggaggcca ctgacagtgg 900

 caacatcgat gcggccaaag acatcatccg ctacatcatc gggattggaa 950

 agcattttca gaccaaggag agtcaggaga ccctccacaa atttgcatca 1000

 aaacccgcga gcgagtttgt gaaaattctg gacacatttg agaagctgaa 1050

 agatctattc actgagctgc agaagaagat ctatgtcatt gagggcacaa 1100

 gcaaacagga cctgacttcc ttcaacatgg agctgtcctc cagcggcatc 1150

 agtgctgacc tcagcagggg ccatgcagtc gtgggggcag taggagccaa 1200

 ggactgggct gggggctttc ttgacctgaa ggcagacctg caggatgaca 1250

 catttattgg gaatgaacca ttgacaccag aagtgagagc aggctatttg 1300

 ggttacaccg tgacctggct gccctcccgg caaaagactt cgttgctggc 1350

 ctcgggagcc cctcgatacc agcacatggg ccgagtgctg ctgttccaag 1400

 agccacaggg cggaggacac tggagccagg tccagacaat ccatgggacc 1450

 cagattggct cttatttcgg tggggagctg tgtggcgtcg acgtggacca 1500

 agatggggag acagagctgc tgctgattgg tgccccactg ttctatgggg 1550

 agcagagagg aggccgggtg tttatctacc agagaagaca gttggggttt 1600

 gaagaagtct cagagctgca gggggacccc ggctacccac tcgggcggtt 1650

 tggagaagcc atcactgctc tgacagacat caacggcgat gggctggtag 1700

 acgtggctgt gggggcccct ctggaggagc agggggctgt gtacatcttc 1750

 aatgggaggc acggggggct tagtccccag ccaagtcagc ggatagaagg 1800

 gacccaagtg ctctcaggaa ttcagtggtt tggacgctcc atccatgggg 1850

 tgaaggacct tgaaggggat ggcttggcag atgtggctgt gggggctgag 1900

 agccagatga tcgtgctgag ctcccggccc gtggtggata tggtcaccct 1950

 gatgtccttc tctccagctg agatcccagt gcatgaagtg gagtgctcct 2000

 attcaaccag taacaagatg aaagaaggag ttaatatcac aatctgtttc 2050

 cagatcaagt ctctctaccc ccagttccaa ggccgcctgg ttgccaatct 2100

 cacttacact ctgcagctgg atggccaccg gaccagaaga cgggggttgt 2150

 tcccaggagg gagacatgaa ctcagaagga atatagctgt caccaccagc 2200

 atgtcatgca ctgacttctc atttcatttc ccggtatgtg ttcaagacct 2250

 catctccccc atcaatgttt ccctgaattt ctctctttgg gaggaggaag 2300

 ggacaccgag ggaccaaagg gcgcagggca aggacatacc gcccatcctg 2350

 agaccctccc tgcactcgga aacctgggag atcccttttg agaagaactg 2400

 tggggaggac aagaagtgtg aggcaaactt gagagtgtcc ttctctcctg 2450

 caagatccag agccctgcgt ctaactgctt ttgccagcct ctctgtggag 2500

 ctgagcctga gtaacttgga agaagatgct tactgggtcc agctggacct 2550

 gcacttcccc ccgggactct ccttccgcaa ggtggagatg ctgaagcccc 2600

 atagccagat acctgtgagc tgcgaggagc ttcctgaaga gtccaggctt 2650

 ctgtccaggg cattatcttg caatgtgagc tctcccatct tcaaagcagg 2700

 ccactcggtt gctctgcaga tgatgtttaa tacactggta aacagctcct 2750

 ggggggactc ggttgaattg cacgccaatg tgacctgtaa caatgaggac 2800

 tcagacctcc tggaggacaa ctcagccact accatcatcc ccatcctgta 2850

 ccccatcaac atcctcatcc aggaccaaga agactccaca ctctatgtca 2900

 gtttcacccc caaaggcccc aagatccacc aagtcaagca catgtaccag 2950

 gtgaggatcc agccttccat ccacgaccac aacataccca ccctggaggc 3000

 tgtggttggg gtgccacagc ctcccagcga ggggcccatc acacaccagt 3050

 ggagcgtgca gatggagcct cccgtgccct gccactatga ggatctggag 3100

 aggctcccgg atgcagctga gccttgtctc cccggagccc tgttccgctg 3150

 ccctgttgtc ttcaggcagg agatcctcgt ccaagtgatc gggactctgg 3200

 agctggtggg agagatcgag gcctcttcca tgttcagcct ctgcagctcc 3250

 ctctccatct ccttcaacag cagcaagcat ttccacctct atggcagcaa 3300

 cgcctccctg gcccaggttg tcatgaaggt tgacgtggtg tatgagaagc 3350

 agatgctcta cctctacgtg ctgagcggca tcggggggct gctgctgctg 3400

 ctgctcattt tcatagtgct gtacaaggtt ggtttcttca aacggaacct 3450

 gaaggagaag atggaggctg gcagaggtgt cccgaatgga atccctgcag 3500

 aagactctga gcagctggca tctgggcaag aggctgggga tcccggctgc 3550

 ctgaagcccc tccatgagaa ggactctgag agtggtggtg gcaaggactg 3600

 agtccaggcc tgtgaggtgc agagtgccca gaactggact caggatgccc 3650

 agggccactc tgcctctgcc tgcattctgc cgtgtgccct cgggcgagtc 3700

 actgcctctc cctggccctc agtttcccta tctcgaacat ggaactcatt 3750

 cctgaatgtc tcctttgcag gctcataggg aagacctgct gagggaccag 3800

 ccaagagggc tgcaaaagtg agggcttgtc attaccagac ggttcaccag 3850

 cctctcttgg ttccttcctt ggaagagaat gtctgatcta aatgtggaga 3900

 aactgtagtc tcaggaccta gggatgttct ggccctcacc cctgccctgg 3950

 gatgtccaca gatgcctcca ccccccagaa cctgtccttg cacactcccc 4000

 tgcactggag tccagtctct tctgctggca gaaagcaaat gtgacctgtg 4050

 tcactacgtg actgtggcac acgccttgtt cttggccaaa gaccaaattc 4100

 cttggcatgc cttccagcac cctgcaaaat gagaccctcg tggccttccc 4150

 cagcctcttc tagagccgtg atgcctccct gttgaagctc tggtgacacc 4200

 agcctttctc ccaggccagg ctccttcctg tcttcctgca ttcacccaga 4250

 cagctccctc tgcctgaacc ttccatctcg cccacccctc cttccttgac 4300

 cagcagatcc cagctcacgt cacacacttg gttgggtcct cacatctttc 4350

 acacttccac caccctgcac tactccctca aagcacacgt catgtttctt 4400

 catccggcag cctggatgtt ttttccctgt ttaatgattg acgtacttag 4450

 cagctatctc tcagtgaact gtgagggtaa aggctatact tgtcttgttc 4500

 accttgggat gacgccgcat gatatgtcag ggcgtgggac atctagtagg 4550

 tgcttgacat aatttcactg aattaatgac agagccagtg ggaagataca 4600

 gaaaaagagg gccggggctg ggcgcggtgg ttcacgcctg taatcccagc 4650

 actttgggag gccaaggagg gtggatcacc tgaggtcagg agttagaggc 4700

 cagcctggcg aaaccccatc tctactaaaa atacaaaatc caggcgtggt 4750

 ggcacacacc tgtagtccca gctactcagg aggttgaggt aggagaattg 4800

 cttgaacctg ggaggtggag gttgcagtga gccaagattg cgccattgca 4850

 ctccagcctg ggcaacacag cgagactccg tctcaaggaa aaaataaaaa 4900

 taaaaagcgg gcacgggccc ggacatcccc acccttggag gctgtcttct 4950

 caggctctgc cctgccctag ctccacaccc tctcccagga cccatcacgc 5000

 ctgtgcagtg gcccccacag aaagactgag ctcaaggtgg gaaccacgtc 5050

 tgctaacttg gagccccagt gccaagcaca gtgcctgcat gtatttatcc 5100

 aataaatgtg aaattctgtc caaaaaaaaa aaa 5133

<210> 5462
<211> 1170
<212> PRT
<213> Homo sapien

<400> 5462
 Met Lys Asp Ser Cys Ile Thr Val Met Ala Met Ala Leu Leu Ser
   1               5                  10                  15

 Gly Phe Phe Phe Phe Ala Pro Ala Ser Ser Tyr Asn Leu Asp Val
                  20                  25                  30

 Arg Gly Ala Arg Ser Phe Ser Pro Pro Arg Ala Gly Arg His Phe
                  35                  40                  45

 Gly Tyr Arg Val Leu Gln Val Gly Asn Gly Val Ile Val Gly Ala
                  50                  55                  60

 Pro Gly Glu Gly Asn Ser Thr Gly Ser Leu Tyr Gln Cys Gln Ser
                  65                  70                  75

 Gly Thr Gly His Cys Leu Pro Val Thr Leu Arg Gly Ser Asn Tyr
                  80                  85                  90

 Thr Ser Lys Tyr Leu Gly Met Thr Leu Ala Thr Asp Pro Thr Asp
                  95                 100                 105

 Gly Ser Ile Leu Ala Cys Asp Pro Gly Leu Ser Arg Thr Cys Asp
                 110                 115                 120

 Gln Asn Thr Tyr Leu Ser Gly Leu Cys Tyr Leu Phe Arg Gln Asn
                 125                 130                 135

 Leu Gln Gly Pro Met Leu Gln Gly Arg Pro Gly Phe Gln Glu Cys
                 140                 145                 150

 Ile Lys Gly Asn Val Asp Leu Val Phe Leu Phe Asp Gly Ser Met
                 155                 160                 165

 Ser Leu Gln Pro Asp Glu Phe Gln Lys Ile Leu Asp Phe Met Lys
                 170                 175                 180

 Asp Val Met Lys Lys Leu Ser Asn Thr Ser Tyr Gln Phe Ala Ala
                 185                 190                 195

 Val Gln Phe Ser Thr Ser Tyr Lys Thr Glu Phe Asp Phe Ser Asp
                 200                 205                 210

 Tyr Val Lys Trp Lys Asp Pro Asp Ala Leu Leu Lys His Val Lys
                 215                 220                 225

 His Met Leu Leu Leu Thr Asn Thr Phe Gly Ala Ile Asn Tyr Val
                 230                 235                 240

 Ala Thr Glu Val Phe Arg Glu Glu Leu Gly Ala Arg Pro Asp Ala
                 245                 250                 255

 Thr Lys Val Leu Ile Ile Ile Thr Asp Gly Glu Ala Thr Asp Ser
                 260                 265                 270

 Gly Asn Ile Asp Ala Ala Lys Asp Ile Ile Arg Tyr Ile Ile Gly
                 275                 280                 285

 Ile Gly Lys His Phe Gln Thr Lys Glu Ser Gln Glu Thr Leu His
                 290                 295                 300

 Lys Phe Ala Ser Lys Pro Ala Ser Glu Phe Val Lys Ile Leu Asp
                 305                 310                 315

 Thr Phe Glu Lys Leu Lys Asp Leu Phe Thr Glu Leu Gln Lys Lys
                 320                 325                 330

 Ile Tyr Val Ile Glu Gly Thr Ser Lys Gln Asp Leu Thr Ser Phe
                 335                 340                 345

 Asn Met Glu Leu Ser Ser Ser Gly Ile Ser Ala Asp Leu Ser Arg
                 350                 355                 360

 Gly His Ala Val Val Gly Ala Val Gly Ala Lys Asp Trp Ala Gly
                 365                 370                 375

 Gly Phe Leu Asp Leu Lys Ala Asp Leu Gln Asp Asp Thr Phe Ile
                 380                 385                 390

 Gly Asn Glu Pro Leu Thr Pro Glu Val Arg Ala Gly Tyr Leu Gly
                 395                 400                 405

 Tyr Thr Val Thr Trp Leu Pro Ser Arg Gln Lys Thr Ser Leu Leu
                 410                 415                 420

 Ala Ser Gly Ala Pro Arg Tyr Gln His Met Gly Arg Val Leu Leu
                 425                 430                 435

 Phe Gln Glu Pro Gln Gly Gly Gly His Trp Ser Gln Val Gln Thr
                 440                 445                 450

 Ile His Gly Thr Gln Ile Gly Ser Tyr Phe Gly Gly Glu Leu Cys
                 455                 460                 465

 Gly Val Asp Val Asp Gln Asp Gly Glu Thr Glu Leu Leu Leu Ile
                 470                 475                 480

 Gly Ala Pro Leu Phe Tyr Gly Glu Gln Arg Gly Gly Arg Val Phe
                 485                 490                 495

 Ile Tyr Gln Arg Arg Gln Leu Gly Phe Glu Glu Val Ser Glu Leu
                 500                 505                 510

 Gln Gly Asp Pro Gly Tyr Pro Leu Gly Arg Phe Gly Glu Ala Ile
                 515                 520                 525

 Thr Ala Leu Thr Asp Ile Asn Gly Asp Gly Leu Val Asp Val Ala
                 530                 535                 540

 Val Gly Ala Pro Leu Glu Glu Gln Gly Ala Val Tyr Ile Phe Asn
                 545                 550                 555

 Gly Arg His Gly Gly Leu Ser Pro Gln Pro Ser Gln Arg Ile Glu
                 560                 565                 570

 Gly Thr Gln Val Leu Ser Gly Ile Gln Trp Phe Gly Arg Ser Ile
                 575                 580                 585

 His Gly Val Lys Asp Leu Glu Gly Asp Gly Leu Ala Asp Val Ala
                 590                 595                 600

 Val Gly Ala Glu Ser Gln Met Ile Val Leu Ser Ser Arg Pro Val
                 605                 610                 615

 Val Asp Met Val Thr Leu Met Ser Phe Ser Pro Ala Glu Ile Pro
                 620                 625                 630

 Val His Glu Val Glu Cys Ser Tyr Ser Thr Ser Asn Lys Met Lys
                 635                 640                 645

 Glu Gly Val Asn Ile Thr Ile Cys Phe Gln Ile Lys Ser Leu Tyr
                 650                 655                 660

 Pro Gln Phe Gln Gly Arg Leu Val Ala Asn Leu Thr Tyr Thr Leu
                 665                 670                 675

 Gln Leu Asp Gly His Arg Thr Arg Arg Arg Gly Leu Phe Pro Gly
                 680                 685                 690

 Gly Arg His Glu Leu Arg Arg Asn Ile Ala Val Thr Thr Ser Met
                 695                 700                 705

 Ser Cys Thr Asp Phe Ser Phe His Phe Pro Val Cys Val Gln Asp
                 710                 715                 720

 Leu Ile Ser Pro Ile Asn Val Ser Leu Asn Phe Ser Leu Trp Glu
                 725                 730                 735

 Glu Glu Gly Thr Pro Arg Asp Gln Arg Ala Gln Gly Lys Asp Ile
                 740                 745                 750

 Pro Pro Ile Leu Arg Pro Ser Leu His Ser Glu Thr Trp Glu Ile
                 755                 760                 765

 Pro Phe Glu Lys Asn Cys Gly Glu Asp Lys Lys Cys Glu Ala Asn
                 770                 775                 780

 Leu Arg Val Ser Phe Ser Pro Ala Arg Ser Arg Ala Leu Arg Leu
                 785                 790                 795

 Thr Ala Phe Ala Ser Leu Ser Val Glu Leu Ser Leu Ser Asn Leu
                 800                 805                 810

 Glu Glu Asp Ala Tyr Trp Val Gln Leu Asp Leu His Phe Pro Pro
                 815                 820                 825

 Gly Leu Ser Phe Arg Lys Val Glu Met Leu Lys Pro His Ser Gln
                 830                 835                 840

 Ile Pro Val Ser Cys Glu Glu Leu Pro Glu Glu Ser Arg Leu Leu
                 845                 850                 855

 Ser Arg Ala Leu Ser Cys Asn Val Ser Ser Pro Ile Phe Lys Ala
                 860                 865                 870

 Gly His Ser Val Ala Leu Gln Met Met Phe Asn Thr Leu Val Asn
                 875                 880                 885

 Ser Ser Trp Gly Asp Ser Val Glu Leu His Ala Asn Val Thr Cys
                 890                 895                 900

 Asn Asn Glu Asp Ser Asp Leu Leu Glu Asp Asn Ser Ala Thr Thr
                 905                 910                 915

 Ile Ile Pro Ile Leu Tyr Pro Ile Asn Ile Leu Ile Gln Asp Gln
                 920                 925                 930

 Glu Asp Ser Thr Leu Tyr Val Ser Phe Thr Pro Lys Gly Pro Lys
                 935                 940                 945

 Ile His Gln Val Lys His Met Tyr Gln Val Arg Ile Gln Pro Ser
                 950                 955                 960

 Ile His Asp His Asn Ile Pro Thr Leu Glu Ala Val Val Gly Val
                 965                 970                 975

 Pro Gln Pro Pro Ser Glu Gly Pro Ile Thr His Gln Trp Ser Val
                 980                 985                 990

 Gln Met Glu Pro Pro Val Pro Cys His Tyr Glu Asp Leu Glu Arg
                 995                1000                1005

 Leu Pro Asp Ala Ala Glu Pro Cys Leu Pro Gly Ala Leu Phe Arg
                1010                1015                1020

 Cys Pro Val Val Phe Arg Gln Glu Ile Leu Val Gln Val Ile Gly
                1025                1030                1035

 Thr Leu Glu Leu Val Gly Glu Ile Glu Ala Ser Ser Met Phe Ser
                1040                1045                1050

 Leu Cys Ser Ser Leu Ser Ile Ser Phe Asn Ser Ser Lys His Phe
                1055                1060                1065

 His Leu Tyr Gly Ser Asn Ala Ser Leu Ala Gln Val Val Met Lys
                1070                1075                1080

 Val Asp Val Val Tyr Glu Lys Gln Met Leu Tyr Leu Tyr Val Leu
                1085                1090                1095

 Ser Gly Ile Gly Gly Leu Leu Leu Leu Leu Leu Ile Phe Ile Val
                1100                1105                1110

 Leu Tyr Lys Val Gly Phe Phe Lys Arg Asn Leu Lys Glu Lys Met
                1115                1120                1125

 Glu Ala Gly Arg Gly Val Pro Asn Gly Ile Pro Ala Glu Asp Ser
                1130                1135                1140

 Glu Gln Leu Ala Ser Gly Gln Glu Ala Gly Asp Pro Gly Cys Leu
                1145                1150                1155

 Lys Pro Leu His Glu Lys Asp Ser Glu Ser Gly Gly Gly Lys Asp
                1160                1165                1170

<210> 5463
<211> 3700
<212> DNA
<213> Homo sapien

<400> 5463
 agccgccgcc acccgccgcg cccgacaccc gggaggcccc gccagcccgc 50

 gggagaggcc cagcgggagt cgcggaacag caggcccgag cccaccgcgc 100

 cgggccccgg acgccgcgcg gaaaagatga atttacaacc aattttctgg 150

 attggactga tcagttcagt ttgctgtgtg tttgctcaaa cagatgaaaa 200

 tagatgttta aaagcaaatg ccaaatcatg tggagaatgt atacaagcag 250

 ggccaaattg tgggtggtgc acaaattcaa catttttaca ggaaggaatg 300

 cctacttctg cacgatgtga tgatttagaa gccttaaaaa agaagggttg 350

 ccctccagat gacatagaaa atcccagagg ctccaaagat ataaagaaaa 400

 ataaaaatgt aaccaaccgt agcaaaggaa cagcagagaa gctcaagcca 450

 gaggatatta ctcagatcca accacagcag ttggttttgc gattaagatc 500

 aggggagcca cagacattta cattaaaatt caagagagct gaagactatc 550

 ccattgacct ctactacctt atggacctgt cttactcaat gaaagacgat 600

 ttggagaatg taaaaagtct tggaacagat ctgatgaatg aaatgaggag 650

 gattacttcg gacttcagaa ttggatttgg ctcatttgtg gaaaagactg 700

 tgatgcctta cattagcaca acaccagcta agctcaggaa cccttgcaca 750

 agtgaacaga actgcaccag cccatttagc tacaaaaatg tgctcagtct 800

 tactaataaa ggagaagtat ttaatgaact tgttggaaaa cagcgcatat 850

 ctggaaattt ggattctcca gaaggtggtt tcgatgccat catgcaagtt 900

 gcagtttgtg gatcactgat tggctggagg aatgttacac ggctgctggt 950

 gttttccaca gatgccgggt ttcactttgc tggagatggg aaacttggtg 1000

 gcattgtttt accaaatgat ggacaatgtc acctggaaaa taatatgtac 1050

 acaatgagcc attattatga ttatccttct attgctcacc ttgtccagaa 1100

 actgagtgaa aataatattc agacaatttt tgcagttact gaagaatttc 1150

 agcctgttta caaggagctg aaaaacttga tccctaagtc agcagtagga 1200

 acattatctg caaattctag caatgtaatt cagttgatca ttgatgcata 1250

 caattccctt tcctcagaag tcattttgga aaacggcaaa ttgtcagaag 1300

 gagtaacaat aagttacaaa tcttactgca agaacggggt gaatggaaca 1350

 ggggaaaatg gaagaaaatg ttccaatatt tccattggag atgaggttca 1400

 atttgaaatt agcataactt caaataagtg tccaaaaaag gattctgaca 1450

 gctttaaaat taggcctctg ggctttacgg aggaagtaga ggttattctt 1500

 cagtacatct gtgaatgtga atgccaaagc gaaggcatcc ctgaaagtcc 1550

 caagtgtcat gaaggaaatg ggacatttga gtgtggcgcg tgcaggtgca 1600

 atgaagggcg tgttggtaga cattgtgaat gcagcacaga tgaagttaac 1650

 agtgaagaca tggatgctta ctgcaggaaa gaaaacagtt cagaaatctg 1700

 cagtaacaat ggagagtgcg tctgcggaca gtgtgtttgt aggaagaggg 1750

 ataatacaaa tgaaatttat tctggcaaat tctgcgagtg tgataatttc 1800

 aactgtgata gatccaatgg cttaatttgt ggaggaaatg gtgtttgcaa 1850

 gtgtcgtgtg tgtgagtgca accccaacta cactggcagt gcatgtgact 1900

 gttctttgga tactagtact tgtgaagcca gcaacggaca gatctgcaat 1950

 ggccggggca tctgcgagtg tggtgtctgt aagtgtacag atccgaagtt 2000

 tcaagggcaa acgtgtgaga tgtgtcagac ctgccttggt gtctgtgctg 2050

 agcataaaga atgtgttcag tgcagagcct tcaataaagg agaaaagaaa 2100

 gacacatgca cacaggaatg ttcctatttt aacattacca aggtagaaag 2150

 tcgggacaaa ttaccccagc cggtccaacc tgatcctgtg tcccattgta 2200

 aggagaagga tgttgacgac tgttggttct attttacgta ttcagtgaat 2250

 gggaacaacg aggtcatggt tcatgttgtg gagaatccag agtgtcccac 2300

 tggtccagac atcattccaa ttgtagctgg tgtggttgct ggaattgttc 2350

 ttattggcct tgcattactg ctgatatgga agcttttaat gataattcat 2400

 gacagaaggg agtttgctaa atttgaaaag gagaaaatga atgccaaatg 2450

 ggacacgggt gaaaatccta tttataagag tgccgtaaca actgtggtca 2500

 atccgaagta tgagggaaaa tgagtactgc ccgtgcaaat cccacaacac 2550

 tgaatgcaaa gtagcaattt ccatagtcac agttaggtag ctttagggca 2600

 atattgccat ggttttactc atgtgcaggt tttgaaaatg tacaatatgt 2650

 ataattttta aaatgtttta ttattttgaa aataatgttg taattcatgc 2700

 cagggactga caaaagactt gagacaggat ggttattctt gtcagctaag 2750

 gtcacattgt gcctttttga ccttttcttc ctggactatt gaaatcaagc 2800

 ttattggatt aagtgatatt tctatagcga ttgaaagggc aatagttaaa 2850

 gtaatgagca tgatgagagt ttctgttaat catgtattaa aactgatttt 2900

 tagctttaca aatatgtcag tttgcagtta tgcagaatcc aaagtaaatg 2950

 tcctgctagc tagttaagga ttgttttaaa tctgttattt tgctatttgc 3000

 ctgttagaca tgactgatga catatctgaa agacaagtat gttgagagtt 3050

 gctggtgtaa aatacgtttg aaatagttga tctacaaagg ccatgggaaa 3100

 aattcagaga gttaggaagg aaaaaccaat agctttaaaa cctgtgtgcc 3150

 attttaagag ttacttaatg tttggtaact tttatgcctt cactttacaa 3200

 attcaagcct tagataaaag aaccgagcaa ttttctgcta aaaagtcctt 3250

 gatttagcac tatttacata caggccatac tttacaaagt atttgctgaa 3300

 tggggacctt ttgagttgaa tttattttat tatttttatt ttgtttaatg 3350

 tctggtgctt tctatcacct cttctaatct tttaatgtat ttgtttgcaa 3400

 ttttggggta agactttttt atgagtactt tttctttgaa gttttagcgg 3450

 tcaatttgcc tttttaatga acatgtgaag ttatactgtg gctatgcaac 3500

 agctctcacc tacgcgagtc ttactttgag ttagtgccat aacagaccac 3550

 tgtatgttta cttctcacca tttgagttgc ccatcttgtt tcacactagt 3600

 cacattcttg ttttaagtgc ctttagtttt aacagttcac tttttacagt 3650

 gctatttact gaagttattt attaaatatg cctaaaatac ttaaatcgga 3700

<210> 5464
<211> 798
<212> PRT
<213> Homo sapien

<400> 5464
 Met Asn Leu Gln Pro Ile Phe Trp Ile Gly Leu Ile Ser Ser Val
   1               5                  10                  15

 Cys Cys Val Phe Ala Gln Thr Asp Glu Asn Arg Cys Leu Lys Ala
                  20                  25                  30

 Asn Ala Lys Ser Cys Gly Glu Cys Ile Gln Ala Gly Pro Asn Cys
                  35                  40                  45

 Gly Trp Cys Thr Asn Ser Thr Phe Leu Gln Glu Gly Met Pro Thr
                  50                  55                  60

 Ser Ala Arg Cys Asp Asp Leu Glu Ala Leu Lys Lys Lys Gly Cys
                  65                  70                  75

 Pro Pro Asp Asp Ile Glu Asn Pro Arg Gly Ser Lys Asp Ile Lys
                  80                  85                  90

 Lys Asn Lys Asn Val Thr Asn Arg Ser Lys Gly Thr Ala Glu Lys
                  95                 100                 105

 Leu Lys Pro Glu Asp Ile Thr Gln Ile Gln Pro Gln Gln Leu Val
                 110                 115                 120

 Leu Arg Leu Arg Ser Gly Glu Pro Gln Thr Phe Thr Leu Lys Phe
                 125                 130                 135

 Lys Arg Ala Glu Asp Tyr Pro Ile Asp Leu Tyr Tyr Leu Met Asp
                 140                 145                 150

 Leu Ser Tyr Ser Met Lys Asp Asp Leu Glu Asn Val Lys Ser Leu
                 155                 160                 165

 Gly Thr Asp Leu Met Asn Glu Met Arg Arg Ile Thr Ser Asp Phe
                 170                 175                 180

 Arg Ile Gly Phe Gly Ser Phe Val Glu Lys Thr Val Met Pro Tyr
                 185                 190                 195

 Ile Ser Thr Thr Pro Ala Lys Leu Arg Asn Pro Cys Thr Ser Glu
                 200                 205                 210

 Gln Asn Cys Thr Ser Pro Phe Ser Tyr Lys Asn Val Leu Ser Leu
                 215                 220                 225

 Thr Asn Lys Gly Glu Val Phe Asn Glu Leu Val Gly Lys Gln Arg
                 230                 235                 240

 Ile Ser Gly Asn Leu Asp Ser Pro Glu Gly Gly Phe Asp Ala Ile
                 245                 250                 255

 Met Gln Val Ala Val Cys Gly Ser Leu Ile Gly Trp Arg Asn Val
                 260                 265                 270

 Thr Arg Leu Leu Val Phe Ser Thr Asp Ala Gly Phe His Phe Ala
                 275                 280                 285

 Gly Asp Gly Lys Leu Gly Gly Ile Val Leu Pro Asn Asp Gly Gln
                 290                 295                 300

 Cys His Leu Glu Asn Asn Met Tyr Thr Met Ser His Tyr Tyr Asp
                 305                 310                 315

 Tyr Pro Ser Ile Ala His Leu Val Gln Lys Leu Ser Glu Asn Asn
                 320                 325                 330

 Ile Gln Thr Ile Phe Ala Val Thr Glu Glu Phe Gln Pro Val Tyr
                 335                 340                 345

 Lys Glu Leu Lys Asn Leu Ile Pro Lys Ser Ala Val Gly Thr Leu
                 350                 355                 360

 Ser Ala Asn Ser Ser Asn Val Ile Gln Leu Ile Ile Asp Ala Tyr
                 365                 370                 375

 Asn Ser Leu Ser Ser Glu Val Ile Leu Glu Asn Gly Lys Leu Ser
                 380                 385                 390

 Glu Gly Val Thr Ile Ser Tyr Lys Ser Tyr Cys Lys Asn Gly Val
                 395                 400                 405

 Asn Gly Thr Gly Glu Asn Gly Arg Lys Cys Ser Asn Ile Ser Ile
                 410                 415                 420

 Gly Asp Glu Val Gln Phe Glu Ile Ser Ile Thr Ser Asn Lys Cys
                 425                 430                 435

 Pro Lys Lys Asp Ser Asp Ser Phe Lys Ile Arg Pro Leu Gly Phe
                 440                 445                 450

 Thr Glu Glu Val Glu Val Ile Leu Gln Tyr Ile Cys Glu Cys Glu
                 455                 460                 465

 Cys Gln Ser Glu Gly Ile Pro Glu Ser Pro Lys Cys His Glu Gly
                 470                 475                 480

 Asn Gly Thr Phe Glu Cys Gly Ala Cys Arg Cys Asn Glu Gly Arg
                 485                 490                 495

 Val Gly Arg His Cys Glu Cys Ser Thr Asp Glu Val Asn Ser Glu
                 500                 505                 510

 Asp Met Asp Ala Tyr Cys Arg Lys Glu Asn Ser Ser Glu Ile Cys
                 515                 520                 525

 Ser Asn Asn Gly Glu Cys Val Cys Gly Gln Cys Val Cys Arg Lys
                 530                 535                 540

 Arg Asp Asn Thr Asn Glu Ile Tyr Ser Gly Lys Phe Cys Glu Cys
                 545                 550                 555

 Asp Asn Phe Asn Cys Asp Arg Ser Asn Gly Leu Ile Cys Gly Gly
                 560                 565                 570

 Asn Gly Val Cys Lys Cys Arg Val Cys Glu Cys Asn Pro Asn Tyr
                 575                 580                 585

 Thr Gly Ser Ala Cys Asp Cys Ser Leu Asp Thr Ser Thr Cys Glu
                 590                 595                 600

 Ala Ser Asn Gly Gln Ile Cys Asn Gly Arg Gly Ile Cys Glu Cys
                 605                 610                 615

 Gly Val Cys Lys Cys Thr Asp Pro Lys Phe Gln Gly Gln Thr Cys
                 620                 625                 630

 Glu Met Cys Gln Thr Cys Leu Gly Val Cys Ala Glu His Lys Glu
                 635                 640                 645

 Cys Val Gln Cys Arg Ala Phe Asn Lys Gly Glu Lys Lys Asp Thr
                 650                 655                 660

 Cys Thr Gln Glu Cys Ser Tyr Phe Asn Ile Thr Lys Val Glu Ser
                 665                 670                 675

 Arg Asp Lys Leu Pro Gln Pro Val Gln Pro Asp Pro Val Ser His
                 680                 685                 690

 Cys Lys Glu Lys Asp Val Asp Asp Cys Trp Phe Tyr Phe Thr Tyr
                 695                 700                 705

 Ser Val Asn Gly Asn Asn Glu Val Met Val His Val Val Glu Asn
                 710                 715                 720

 Pro Glu Cys Pro Thr Gly Pro Asp Ile Ile Pro Ile Val Ala Gly
                 725                 730                 735

 Val Val Ala Gly Ile Val Leu Ile Gly Leu Ala Leu Leu Leu Ile
                 740                 745                 750

 Trp Lys Leu Leu Met Ile Ile His Asp Arg Arg Glu Phe Ala Lys
                 755                 760                 765

 Phe Glu Lys Glu Lys Met Asn Ala Lys Trp Asp Thr Gly Glu Asn
                 770                 775                 780

 Pro Ile Tyr Lys Ser Ala Val Thr Thr Val Val Asn Pro Lys Tyr
                 785                 790                 795

 Glu Gly Lys


<210> 5465
<211> 2553
<212> DNA
<213> Homo sapien

<400> 5465
 cccacgcgtc cgcggacgcg tgggcggacg cgtgggtgcg ccgctgaacg 50

 gatggctgag ggagccccgc ggatcgttta ggaaagccgg ccagctgatc 100

 gtcgtgtgtt gccacccatt catgtcaaga tgactaagtt tggatttttg 150

 cgattgtcct atgagaagca ggacacactt ttgaagcttc tcattctgtc 200

 aatggctgct gtattatcct tctccactcg tctgtttgct gtcctgagat 250

 ttgaaagtgt tatccatgag tttgatccgt actttaatta tcggactacc 300

 aggttcctgg ctgaggaggg gttttataaa ttccataact ggtttgatga 350

 ccgagcctgg taccctttgg gacgaatcat tggaggaaca atttacccag 400

 gtttaatgat cacctctgct gcaatctacc atgtactcca ttttttccac 450

 atcaccatcg acattcggaa tgtctgtgtg ttcctggccc ctctcttctc 500

 ctccttcacc accatcgtca cgtaccacct taccaaagag ctcaaggatg 550

 caggggctgg gcttcttgct gctgccatga ttgctgtagt tcctggatat 600

 atctcccgat ctgtggctgg ctcctatgat aatgaaggga ttgccatctt 650

 ttgcatgcta ctcacctact acatgtggat caaggcagta aagactggtt 700

 ccatctgttg ggcagctaag tgtgcccttg cttatttcta catggtctcg 750

 tcatggggag gttatgtgtt cctgatcaac ttaattcctc tccacgtcct 800

 cgtgctgatg ctcacaggcc gtttctctca ccggatctat gtggcctact 850

 gtactgttta ctgcctgggc actatacttt ctatgcagat ctcctttgtg 900

 ggtttccagc ctgtcctttc atcagagcac atggcagcct ttggggtctt 950

 tggtctctgc cagatccatg cctttgtgga ttacctgcgc agcaagttga 1000

 atccacaaca atttgaagtt cttttccgga gcgtcatctc tctggtaggc 1050

 tttgtccttc tcaccgtggg agctctcctc atgctgacag gaaaaatatc 1100

 tccctggacg gggcgtttct actcgctgct ggatccctct tatgctaaga 1150

 acaacatccc catcattgct tctgtgtctg agcatcagcc cacaacctgg 1200

 tcctcatact attttgacct gcagctcctc gtcttcatgt ttccagttgg 1250

 cctctattac tgctttagca acctgtctga tgcccggatt tttatcatca 1300

 tgtatggtgt gaccagcatg tacttttcag ctgtaatggt gcgtctaatg 1350

 ctagtgttgg cacctgttat gtgcattctc tctggcattg gagtctccca 1400

 ggtgctgtcc acatacatga agaatctgga cataagtcgt ccagacaaga 1450

 agagcaagaa gcaacaggat tccacctacc ctattaagaa tgaagtggca 1500

 agtgggatga tactggtcat ggctttcttt ctcatcacct acacctttca 1550

 ttcaacctgg gtgaccagtg aggcctactc ttctccgtcc attgtactat 1600

 ctgcccgtgg tggggatggc agtaggatca tatttgatga cttccgagaa 1650

 gcatattatt ggcttcgtca taatactcca gaggatgcga aggtcatgtc 1700

 ctggtgggat tatggctatc agattacagc tatggcaaac cgaacaattt 1750

 tagtggacaa taacacatgg aataataccc atatttctcg agtagggcag 1800

 gcaatggcgt ccacagagga aaaagcctat gagatcatga gggagctcga 1850

 tgtcagctat gtgctggtca tttttggagg cctcactggg tattcctctg 1900

 atgatatcaa caagtttctt tggatggtcc ggattggagg gagcacagat 1950

 acaggcaaac atatcaagga gaatgactat tatactccaa ctggggagtt 2000

 ccgtgtggac cgtgaaggtt ctccagtgct gctcaactgc ctcatgtaca 2050

 agatgtgtta ctatcgcttt ggacaggttt acacagaagc caagcgtcct 2100

 ccaggctttg accgtgtccg aaatgctgag attgggaata aagactttga 2150

 gcttgatgtc ctggaggaag catataccac agaacattgg ctggtcagga 2200

 tatacaaggt aaaggacctg gataatcgag gcttgtcaag gacataaatg 2250

 tcacgtccag ctctgatatg cttcgcactg agcacatcac atttaggacg 2300

 ttgaagattt tttttttttt ttttttttta atatgcagtt tgtaagaaca 2350

 aaactggatg gcatcagaat tgtctggaag ttttgtcttg ggcagtatgg 2400

 gctgggccaa atgaaatgat ttttataatt ctaaacaggt taccaaatga 2450

 aatgtcatgg ctttactttg gtcaattaaa ggggggaatt tttttaaaaa 2500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2550

 aaa 2553

<210> 5466
<211> 705
<212> PRT
<213> Homo sapien

<400> 5466
 Met Thr Lys Phe Gly Phe Leu Arg Leu Ser Tyr Glu Lys Gln Asp
   1               5                  10                  15

 Thr Leu Leu Lys Leu Leu Ile Leu Ser Met Ala Ala Val Leu Ser
                  20                  25                  30

 Phe Ser Thr Arg Leu Phe Ala Val Leu Arg Phe Glu Ser Val Ile
                  35                  40                  45

 His Glu Phe Asp Pro Tyr Phe Asn Tyr Arg Thr Thr Arg Phe Leu
                  50                  55                  60

 Ala Glu Glu Gly Phe Tyr Lys Phe His Asn Trp Phe Asp Asp Arg
                  65                  70                  75

 Ala Trp Tyr Pro Leu Gly Arg Ile Ile Gly Gly Thr Ile Tyr Pro
                  80                  85                  90

 Gly Leu Met Ile Thr Ser Ala Ala Ile Tyr His Val Leu His Phe
                  95                 100                 105

 Phe His Ile Thr Ile Asp Ile Arg Asn Val Cys Val Phe Leu Ala
                 110                 115                 120

 Pro Leu Phe Ser Ser Phe Thr Thr Ile Val Thr Tyr His Leu Thr
                 125                 130                 135

 Lys Glu Leu Lys Asp Ala Gly Ala Gly Leu Leu Ala Ala Ala Met
                 140                 145                 150

 Ile Ala Val Val Pro Gly Tyr Ile Ser Arg Ser Val Ala Gly Ser
                 155                 160                 165

 Tyr Asp Asn Glu Gly Ile Ala Ile Phe Cys Met Leu Leu Thr Tyr
                 170                 175                 180

 Tyr Met Trp Ile Lys Ala Val Lys Thr Gly Ser Ile Cys Trp Ala
                 185                 190                 195

 Ala Lys Cys Ala Leu Ala Tyr Phe Tyr Met Val Ser Ser Trp Gly
                 200                 205                 210

 Gly Tyr Val Phe Leu Ile Asn Leu Ile Pro Leu His Val Leu Val
                 215                 220                 225

 Leu Met Leu Thr Gly Arg Phe Ser His Arg Ile Tyr Val Ala Tyr
                 230                 235                 240

 Cys Thr Val Tyr Cys Leu Gly Thr Ile Leu Ser Met Gln Ile Ser
                 245                 250                 255

 Phe Val Gly Phe Gln Pro Val Leu Ser Ser Glu His Met Ala Ala
                 260                 265                 270

 Phe Gly Val Phe Gly Leu Cys Gln Ile His Ala Phe Val Asp Tyr
                 275                 280                 285

 Leu Arg Ser Lys Leu Asn Pro Gln Gln Phe Glu Val Leu Phe Arg
                 290                 295                 300

 Ser Val Ile Ser Leu Val Gly Phe Val Leu Leu Thr Val Gly Ala
                 305                 310                 315

 Leu Leu Met Leu Thr Gly Lys Ile Ser Pro Trp Thr Gly Arg Phe
                 320                 325                 330

 Tyr Ser Leu Leu Asp Pro Ser Tyr Ala Lys Asn Asn Ile Pro Ile
                 335                 340                 345

 Ile Ala Ser Val Ser Glu His Gln Pro Thr Thr Trp Ser Ser Tyr
                 350                 355                 360

 Tyr Phe Asp Leu Gln Leu Leu Val Phe Met Phe Pro Val Gly Leu
                 365                 370                 375

 Tyr Tyr Cys Phe Ser Asn Leu Ser Asp Ala Arg Ile Phe Ile Ile
                 380                 385                 390

 Met Tyr Gly Val Thr Ser Met Tyr Phe Ser Ala Val Met Val Arg
                 395                 400                 405

 Leu Met Leu Val Leu Ala Pro Val Met Cys Ile Leu Ser Gly Ile
                 410                 415                 420

 Gly Val Ser Gln Val Leu Ser Thr Tyr Met Lys Asn Leu Asp Ile
                 425                 430                 435

 Ser Arg Pro Asp Lys Lys Ser Lys Lys Gln Gln Asp Ser Thr Tyr
                 440                 445                 450

 Pro Ile Lys Asn Glu Val Ala Ser Gly Met Ile Leu Val Met Ala
                 455                 460                 465

 Phe Phe Leu Ile Thr Tyr Thr Phe His Ser Thr Trp Val Thr Ser
                 470                 475                 480

 Glu Ala Tyr Ser Ser Pro Ser Ile Val Leu Ser Ala Arg Gly Gly
                 485                 490                 495

 Asp Gly Ser Arg Ile Ile Phe Asp Asp Phe Arg Glu Ala Tyr Tyr
                 500                 505                 510

 Trp Leu Arg His Asn Thr Pro Glu Asp Ala Lys Val Met Ser Trp
                 515                 520                 525

 Trp Asp Tyr Gly Tyr Gln Ile Thr Ala Met Ala Asn Arg Thr Ile
                 530                 535                 540

 Leu Val Asp Asn Asn Thr Trp Asn Asn Thr His Ile Ser Arg Val
                 545                 550                 555

 Gly Gln Ala Met Ala Ser Thr Glu Glu Lys Ala Tyr Glu Ile Met
                 560                 565                 570

 Arg Glu Leu Asp Val Ser Tyr Val Leu Val Ile Phe Gly Gly Leu
                 575                 580                 585

 Thr Gly Tyr Ser Ser Asp Asp Ile Asn Lys Phe Leu Trp Met Val
                 590                 595                 600

 Arg Ile Gly Gly Ser Thr Asp Thr Gly Lys His Ile Lys Glu Asn
                 605                 610                 615

 Asp Tyr Tyr Thr Pro Thr Gly Glu Phe Arg Val Asp Arg Glu Gly
                 620                 625                 630

 Ser Pro Val Leu Leu Asn Cys Leu Met Tyr Lys Met Cys Tyr Tyr
                 635                 640                 645

 Arg Phe Gly Gln Val Tyr Thr Glu Ala Lys Arg Pro Pro Gly Phe
                 650                 655                 660

 Asp Arg Val Arg Asn Ala Glu Ile Gly Asn Lys Asp Phe Glu Leu
                 665                 670                 675

 Asp Val Leu Glu Glu Ala Tyr Thr Thr Glu His Trp Leu Val Arg
                 680                 685                 690

 Ile Tyr Lys Val Lys Asp Leu Asp Asn Arg Gly Leu Ser Arg Thr
                 695                 700                 705

<210> 5467
<211> 9517
<212> DNA
<213> Homo sapien

<400> 5467
 gttgctgtcg gagagagaaa gccgcacccg agaggaggtg tgggtgttcc 50

 gcttccatcc taacggaacg agctccctct tcgcggacat gggattaccc 100

 agcggctgct aacccctctc ctcgccctgc tcccccaaac cggcgtggct 150

 ccccgggcac caaggagctg actacagagg agcaggattt gcacccctcg 200

 ctgggcttgc tttggcaaca gagtgcctga cccaggtcag gattttcaag 250

 aaagacatgt ctgacaaaat gtctagcttc ctacatattg gagacatttg 300

 ttctctgtac gcggagggat cgacaaatgg atttattagc accttgggcc 350

 tggttgatga tcgttgtgtt gtacagccag aaaccgggga ccttaacaat 400

 ccacctaaga aattcagaga ctgcctcttt aagctatgtc ccatgaaccg 450

 ctactctgcc caaaagcagt tctggaaagc cgctaagcct ggggccaaca 500

 gcaccacaga cgcagtgcta ctcaacaaac tgcaccacgc tgcagacttg 550

 gaaaagaagc agaatgagac agaaaacagg aaattgctgg ggaccgtaat 600

 ccagtatggc aatgtgatcc agctcctgca tttgaaaagt aataaatacc 650

 taacagtgaa taagaggctt cctgctctgt tggagaagaa tgccatgaga 700

 gtcacattgg acgaggctgg aaatgaaggg tcctggtttt atattcagcc 750

 attctacaag ctgcgatcca ttggagacag cgtggtcata ggtgacaagg 800

 tggttctgaa ccccgtcaat gctggtcagc ccctacatgc tagcagccat 850

 caactggtag ataacccagg ctgcaatgag gtcaattccg tcaactgcaa 900

 tacaagctgg aaaatagtcc ttttcatgaa atggagtgat aacaaagacg 950

 acatattaaa ggggggtgac gtggtgaggc tgtttcatgc tgagcaggag 1000

 aagtttctca cctgtgacga acacaggaag aagcagcacg tcttcctgag 1050

 aaccacgggc cggcagtcgg ccacatctgc caccagttca aaagccctgt 1100

 gggaggtgga ggtggtccag catgacccat gtcggggcgg agcagggtat 1150

 tggaacagcc ttttccgttt caagcatctg gccacggggc attacttggc 1200

 agcagaggtg gaccctgatc aggacgcctc tcgaagtagg ttgcggaatg 1250

 cccaagaaaa gatggtatac tccctggtct ctgtgcctga aggcaatgac 1300

 atctcctcca ttttcgagct agatcccacc actctgcgtg gaggtgacag 1350

 ccttgtccca aggaactctt atgttcggct cagacaccta tgtactaata 1400

 cctgggttca cagcacaaat attcctattg acaaggaaga agaaaagccc 1450

 gtgatgctga aaattggcac ctctcctgtg aaggaggata aggaagcatt 1500

 tgccatagtt ccggtttctc ctgctgaagt tcgggacctg gactttgcca 1550

 atgatgccag caaggtgctg ggctccattg ctgggaagct agagaagggc 1600

 accatcaccc agaatgaaag gaggtctgta accaagctgc tagaagattt 1650

 ggtttacttc gtcactggtg gaactaattc tggtcaagat gttctcgaag 1700

 ttgtcttctc caagcccaac agagaacggc agaaactgat gagagaacag 1750

 aatattctca agcagatctt caagttgtta caagccccat tcacagactg 1800

 cggtgatggc ccaatgcttc ggctggaaga gctcggggac cagcggcacg 1850

 ctcctttcag acacatctgc cggctctgct acagggtgct gagacactcg 1900

 cagcaagact acaggaagaa ccaggagtat atagccaagc agtttggctt 1950

 catgcagaag cagattggct atgatgtgtt ggctgaagac actatcactg 2000

 ccctgctcca caataatcgg aaactcctgg aaaaacacat taccgcggca 2050

 gagattgaca catttgtcag cctggtgcga aagaacaggg agcccagatt 2100

 cttagattac ctctccgacc tctgtgtctc catgaacaaa tcaattccag 2150

 tgacccagga actgatatgt aaagctgtgc tgaaccccac caacgctgac 2200

 atcctgattg agaccaaatt ggttctttct cgttttgaat ttgaaggtgt 2250

 ctcttccact ggagagaatg ctctggaggc aggagaagac gaggaagagg 2300

 tgtggctgtt ttggagggac agcaacaaag agattcgcag caagagtgtg 2350

 agggaattgg ctcaggatgc taaagaaggg cagaaggagg accgagacgt 2400

 tctcagctac tacagatatc agctgaacct ctttgcgagg atgtgtctgg 2450

 accgccaata cctggccatc aacgaaatct caggccagct ggatgtcgat 2500

 ctcattctcc gctgcatgtc tgacgagaac ctgccctatg acctcagggc 2550

 gtccttctgc cgcctcatgc ttcacatgca tgtggaccga gatccccagg 2600

 aacaagtcac ccccgtgaaa tatgcccgcc tctggtcgga gattccctcg 2650

 gagatcgcca ttgacgacta tgatagtagt ggagcttcca aagatgaaat 2700

 taaggagaga tttgctcaga ccatggagtt tgtggaggag tatttaagag 2750

 atgtggtttg tcagaggttc cctttctctg ataaagagaa gaataagctt 2800

 acgtttgagg ttgtaaattt agctaggaat ctcatatact ttggtttcta 2850

 caacttctct gaccttctcc gattaactaa gatccttctg gccatattgg 2900

 actgtgtaca tgtgacaaca atcttcccca ttagcaagat ggcgaaagga 2950

 gaagagaata aaggcagtaa cgtgatgaga tctattcatg gcgtgggaga 3000

 gctgatgacc caggtggtgc tccggggagg aggctttttg cccatgactc 3050

 ccatggctgc tgcccctgaa ggcaatgtga agcaggcaga gcctgagaag 3100

 gaggacatca tggtcatgga caccaagctg aagatcattg agatactcca 3150

 gtttattttg aatgtgaggt tggattatag gatctcctgc ctcctgtgta 3200

 tatttaagcg agagtttgat gaaagcaatt cccagacttc agaaacatcc 3250

 tccggaaaca gcagccaaga agggccaagt aatgtaccag gtgctcttga 3300

 ctttgaacac attgaagaac aagcagaagg catctttgga ggaagtgagg 3350

 agaacacccc actggacttg gatgaccacg gcggcagaac ctttctccgt 3400

 gtcctgctcc acttgacgat gcatgactac ccacccctgg tgtcaggggc 3450

 cctgcagctc ctcttccggc acttcagcca gaggcaggag gtgctccagg 3500

 ccttcaaaca ggttcaactg ctggttacca gccaagatgt ggacaactac 3550

 aaacagatca aacaagactt ggatcaactg aggtccatcg tggaaaagtc 3600

 agagctttgg gtgtacaaag ggcagggccc cgatgagact atggatggtg 3650

 catctggaga aaatgaacat aagaaaacgg aggagggaaa taacaagcca 3700

 caaaagcatg aaagcaccag cagctacaac tacagagtgg tcaaagagat 3750

 tttgattcgg cttagcaaac tctgtgttca agagagtgcc tcagtgagaa 3800

 agagcaggaa gcagcaacag cgtctgctcc ggaacatggg cgcgcacgcc 3850

 gtggtgctgg agctgctgca gattccctat gagaaggccg aagataccaa 3900

 gatgcaagag ataatgaggt tggctcatga atttttgcag aatttctgcg 3950

 caggcaacca gcagaatcaa gctttgctac ataaacacat aaacctgttt 4000

 ctcaacccag ggatcctgga ggcagtaacc atgcagcaca tcttcatgaa 4050

 caatttccag ctttgcagtg agatcaacga gagagttgtt cagcacttcg 4100

 ttcactgcat agagactcac ggtcggaatg tccagtatat aaagttctta 4150

 cagacaattg tcaaggcaga agggaaattt attaaaaaat gccaagacat 4200

 ggttatggcc gagctggtca attcgggaga ggatgtcctc gtgttctaca 4250

 acgacagagc ctctttccag actctgatcc agatgatgcg gtcagaacgg 4300

 gatcggatgg atgagaacag ccctctcatg taccacatcc acttggtcga 4350

 gctcctggct gtgtgcacgg agggtaagaa tgtctacaca gagatcaagt 4400

 gcaactccct gctcccgctg gatgacatcg ttcgcgtggt gacccacgag 4450

 gactgcatcc ctgaggttaa aattgcatac attaacttcc tgaatcactg 4500

 ctatgtggat acagaggtgg aaatgaagga gatttatacc agcaatcaca 4550

 tgtggaaatt gtttgagaat ttccttgtag acatctgcag ggcctgtaac 4600

 aacactagtg acaggaaaca tgcagactcg attttggaga agtatgtcac 4650

 cgaaatcgtc atgagtattg ttactacttt cttcagctct cccttctcag 4700

 accagagtac gactttgcag actcgccagc ctgtctttgt gcaactgctg 4750

 caaggcgtgt tcagggttta ccactgcaac tggttaatgc caagccaaaa 4800

 agcctccgtg gagagctgta ttcgggtgct gtctgatgta gccaagagcc 4850

 gggccattgc cattcccgtg gacctggaca gccaagtcaa caacctcttt 4900

 ctcaagtccc acagcattgt gcagaaaaca gccatgaact ggcggctctc 4950

 agcccgcaat gccgcacgca gggactctgt tctggcagct tccagagact 5000

 accggaatat cattgagaga ttgcaggaca tcgtctccgc gctggaggac 5050

 cgtctcaggc ccctggtgca ggcagagtta tctgtgctcg tggatgttct 5100

 ccacagaccc gagctgcttt tcccagagaa cacagacgcc agaaggaaat 5150

 gtgaaagtgg cggtttcatt tgcaagttaa taaagcatac aaaacagctg 5200

 ctagaagaaa atgaagagaa gctctgcatt aaggtcctac agaccctgag 5250

 ggaaatgatg accaaagata gaggctatgg agaaaagggt gaggcgctca 5300

 ggcaagttct ggtcaaccgt tactatggaa acgtcagacc ttcgggacga 5350

 agagagagcc ttaccagctt tggcaatggc ccactgtcag caggaggacc 5400

 cggcaagccc gggggaggag ggggaggttc cggatccagc tctatgagca 5450

 ggggtgagat gagtctggcc gaggttcagt gtcaccttga caaggagggg 5500

 gcttccaatc tagttatcga cctcatcatg aacgcatcca gtgaccgagt 5550

 gttccatgaa agcattctcc tggccattgc ccttctggaa ggaggcaaca 5600

 ccaccatcca gcactccttt ttctgtcgct tgacagaaga taagaagtca 5650

 gagaaattct ttaaggtgtt ttatgaccgg atgaaggtgg cccagcaaga 5700

 aatcaaagca acagtgacag tgaacaccag tgacttggga aataaaaaga 5750

 aagacgatga ggtagacagg gatgccccat cacggaaaaa agctaaagag 5800

 cccacaacac agataacaga agaggtccgg gatcagctcc tggaggcctc 5850

 cgctgccacc aggaaagcct tcaccacttt caggagggag gctgatcccg 5900

 acgaccacta ccagcctgga gagggcaccc aggccactgc cgacaaggcc 5950

 aaggacgacc tggagatgag cgcggtcatc accatcatgc agcccatcct 6000

 ccgcttcctt cagctcctgt gtgaaaacca caaccgagac ctgcagaact 6050

 tcctccgttg ccaaaataac aagaccaact acaatttggt atgtgagacc 6100

 ctgcagtttc tggactgtat ttgtggaagc acaactggag gccttggtct 6150

 tctgggcttg tatataaatg aaaagaacgt agcgcttatc aaccaaaccc 6200

 tggaaagtct gaccgaatac tgtcaaggac cttgccatga gaaccagaac 6250

 tgcatagcca cccatgaatc caatggcatt gacatcatca cagccctgat 6300

 cctcaatgat atcaatcctt tgggaaagaa gaggatggac cttgtgttag 6350

 aactgaagaa caatgcctcg aagttgctcc tggccatcat ggaaagcagg 6400

 cacgacagtg aaaacgcaga gaggatactt tataacatga ggcccaagga 6450

 actggtggaa gtgatcaaga aagcctacat gcaaggtgaa gtggaatttg 6500

 aggatggaga aaacggtgag gatggggcgg cgtcccccag gaacgtgggg 6550

 cacaacatct acatattagc ccatcagttg gctcggcata acaaagaact 6600

 tcagagcatg ctgaaacctg gtggccaagt ggacggagat gaagccctgg 6650

 agttttatgc caagcacacg gcgcagatag agattgtcag attagaccga 6700

 acaatggaac agatagtctt tcccgtgccc agcatatgtg aattcctaac 6750

 caaggagtca aaactacgaa tttactatac tacagagaga gacgaacaag 6800

 gcagcaaaat caatgatttc tttctgcggt ctgaagacct cttcaatgaa 6850

 atgaattggc agaagaaact gagagcccag cccgtgttgt actggtgtgc 6900

 ccgcaacatg tctttctgga gcagcatttc gtttaacctg gccgtcctga 6950

 tgaacctgct ggtggcgttt ttctacccgt ttaagggagt ccgaggagga 7000

 accctggagc cccactggtc gggactcctg tggacagcca tgctcatctc 7050

 tctggccatc gtcattgccc tccccaagcc ccatggcatc cgggccttaa 7100

 ttgcctccac aattctacga ctgatatttt cagtcgggtt acaacccacg 7150

 ttgtttcttc tgggcgcttt caatgtatgc aataaaatca tctttctaat 7200

 gagctttgtg ggcaactgtg ggacattcac aagaggctac cgagccatgg 7250

 ttctggatgt tgagttcctc tatcatttgt tgtatctggt gatctgtgcc 7300

 atggggctct ttgtccatga attcttctac agtctgctgc tttttgattt 7350

 agtgtacaga gaagagactt tgcttaatgt cattaaaagt gtcactcgca 7400

 atggacggtc catcatcctg acagcagttc tggctctgat cctcgtttac 7450

 ctgttctcaa tagtgggcta tcttttcttc aaggatgact ttatcttgga 7500

 agtagatagg ctgcccaatg aaacagctgt tccagaaacc ggcgagagtt 7550

 tggcaagcga gttcctgttc tccgatgtgt gtagggtgga gagtggggag 7600

 aactgctcct ctcctgcacc cagagaagag ctggtccctg cagaagagac 7650

 ggaacaggat aaagagcaca catgtgagac gctgctgatg tgcattgtca 7700

 ccgtgctgag tcacgggctg cggagcgggg gtggagtagg agatgtactc 7750

 aggaaaccgt ccaaagagga acccctgttt gctgctagag ttatttatga 7800

 cctcttgttc ttcttcatgg tcatcatcat tgttcttaac ctgatttttg 7850

 gggttatcat tgacactttt gctgacctga ggagtgagaa gcagaagaag 7900

 gaagagatct tgaagaccac gtgctttatc tgtggcttgg aaagagacaa 7950

 gtttgacaac aagactgtca cctttgaaga gcacatcaag gaagaacaca 8000

 acatgtggca ctatctgtgc ttcatcgtcc tggtgaaagt aaaggactcc 8050

 accgaatata ctgggcctga gagttacgtg gcagaaatga tcaaggaaag 8100

 aaaccttgac tggttcccca ggatgagagc catgtcattg gtcagcagtg 8150

 attctgaagg agaacagaat gagctgagaa acctgcagga gaagctggag 8200

 tccaccatga aacttgtcac gaacctttct ggccagctgt cggaattaaa 8250

 ggatcagatg acagaacaaa ggaagcagaa acaaagaatt ggtcttctag 8300

 gacatcctcc tcacatgaat gtcaacccac aacaaccagc ataagcaaat 8350

 gaaagaaagg aattgtattt accttttata attattatta gtgtgggtat 8400

 ggctaatgag ttctgattca cccacgaagg ttacatttat gctgaataca 8450

 tttgtaaata ctcagtttta tactgtatgt atatgattgc tactctaaag 8500

 gtttggatat atgtattgta attagaattg ttggcatgat gacatttcat 8550

 ttgtgccaaa aatattaaaa atgccttttt tggaaggact aacagaaagc 8600

 acctgatttg cacttgaacc agattataga tttaaaagta tatgacatgt 8650

 attttgtatt taaaactaga atagccagta tttatgtttt ttataaaact 8700

 gtgcaatacg aattatgcaa tcacaataca tttgtagctc ccgagtgtcc 8750

 taaagggagt gcacttcttt gaagctggtg tgttaatact atgtaataaa 8800

 tggttaactt tcaaatgatg ctgctgccaa aattatatta atagtgagtt 8850

 tcaggcccct gggcattttg taccatgtaa ttatcctctg gtgatgctgt 8900

 ttctcgttag tggcagtagt gcctccgtct cctagtgata atgctccaag 8950

 tctatgaact gttaaatcag cattcatttt aagaaaagca actttagttt 9000

 caaagatact tttaagcttc taaattgatc atttaaacta tttctttaaa 9050

 taagagagcc aaattagagg ctcatacttt agcttgtgaa gaagataatg 9100

 aattttttaa agggaacttt ctatgcaatg ttcaggataa atcgatactg 9150

 ctggccaatc agtgtcatct cctgggtaaa ttttgatgtc gcattataaa 9200

 gacatgcata attgatggtt tctagattat ctagtccaaa caatagagtt 9250

 tattttttct tcatctgaac caacatgcta cagtagctaa gaagtattaa 9300

 aactatatac atccatataa agatgaaata tgaactatct cattagaagt 9350

 catagttgac cacagacatg ttattcttct gaaagagcca cattttggtt 9400

 ttatttcttg tcacatgatt tcttttcttg atggatgaaa aatatgaaat 9450

 gaaatctttt atatctgttg cctagttttg tacatggatc tcattttaca 9500

 agagaatctc tctgcta 9517

<210> 5468
<211> 2695
<212> PRT
<213> Homo sapien

<400> 5468
 Met Ser Asp Lys Met Ser Ser Phe Leu His Ile Gly Asp Ile Cys
   1               5                  10                  15

 Ser Leu Tyr Ala Glu Gly Ser Thr Asn Gly Phe Ile Ser Thr Leu
                  20                  25                  30

 Gly Leu Val Asp Asp Arg Cys Val Val Gln Pro Glu Thr Gly Asp
                  35                  40                  45

 Leu Asn Asn Pro Pro Lys Lys Phe Arg Asp Cys Leu Phe Lys Leu
                  50                  55                  60

 Cys Pro Met Asn Arg Tyr Ser Ala Gln Lys Gln Phe Trp Lys Ala
                  65                  70                  75

 Ala Lys Pro Gly Ala Asn Ser Thr Thr Asp Ala Val Leu Leu Asn
                  80                  85                  90

 Lys Leu His His Ala Ala Asp Leu Glu Lys Lys Gln Asn Glu Thr
                  95                 100                 105

 Glu Asn Arg Lys Leu Leu Gly Thr Val Ile Gln Tyr Gly Asn Val
                 110                 115                 120

 Ile Gln Leu Leu His Leu Lys Ser Asn Lys Tyr Leu Thr Val Asn
                 125                 130                 135

 Lys Arg Leu Pro Ala Leu Leu Glu Lys Asn Ala Met Arg Val Thr
                 140                 145                 150

 Leu Asp Glu Ala Gly Asn Glu Gly Ser Trp Phe Tyr Ile Gln Pro
                 155                 160                 165

 Phe Tyr Lys Leu Arg Ser Ile Gly Asp Ser Val Val Ile Gly Asp
                 170                 175                 180

 Lys Val Val Leu Asn Pro Val Asn Ala Gly Gln Pro Leu His Ala
                 185                 190                 195

 Ser Ser His Gln Leu Val Asp Asn Pro Gly Cys Asn Glu Val Asn
                 200                 205                 210

 Ser Val Asn Cys Asn Thr Ser Trp Lys Ile Val Leu Phe Met Lys
                 215                 220                 225

 Trp Ser Asp Asn Lys Asp Asp Ile Leu Lys Gly Gly Asp Val Val
                 230                 235                 240

 Arg Leu Phe His Ala Glu Gln Glu Lys Phe Leu Thr Cys Asp Glu
                 245                 250                 255

 His Arg Lys Lys Gln His Val Phe Leu Arg Thr Thr Gly Arg Gln
                 260                 265                 270

 Ser Ala Thr Ser Ala Thr Ser Ser Lys Ala Leu Trp Glu Val Glu
                 275                 280                 285

 Val Val Gln His Asp Pro Cys Arg Gly Gly Ala Gly Tyr Trp Asn
                 290                 295                 300

 Ser Leu Phe Arg Phe Lys His Leu Ala Thr Gly His Tyr Leu Ala
                 305                 310                 315

 Ala Glu Val Asp Pro Asp Gln Asp Ala Ser Arg Ser Arg Leu Arg
                 320                 325                 330

 Asn Ala Gln Glu Lys Met Val Tyr Ser Leu Val Ser Val Pro Glu
                 335                 340                 345

 Gly Asn Asp Ile Ser Ser Ile Phe Glu Leu Asp Pro Thr Thr Leu
                 350                 355                 360

 Arg Gly Gly Asp Ser Leu Val Pro Arg Asn Ser Tyr Val Arg Leu
                 365                 370                 375

 Arg His Leu Cys Thr Asn Thr Trp Val His Ser Thr Asn Ile Pro
                 380                 385                 390

 Ile Asp Lys Glu Glu Glu Lys Pro Val Met Leu Lys Ile Gly Thr
                 395                 400                 405

 Ser Pro Val Lys Glu Asp Lys Glu Ala Phe Ala Ile Val Pro Val
                 410                 415                 420

 Ser Pro Ala Glu Val Arg Asp Leu Asp Phe Ala Asn Asp Ala Ser
                 425                 430                 435

 Lys Val Leu Gly Ser Ile Ala Gly Lys Leu Glu Lys Gly Thr Ile
                 440                 445                 450

 Thr Gln Asn Glu Arg Arg Ser Val Thr Lys Leu Leu Glu Asp Leu
                 455                 460                 465

 Val Tyr Phe Val Thr Gly Gly Thr Asn Ser Gly Gln Asp Val Leu
                 470                 475                 480

 Glu Val Val Phe Ser Lys Pro Asn Arg Glu Arg Gln Lys Leu Met
                 485                 490                 495

 Arg Glu Gln Asn Ile Leu Lys Gln Ile Phe Lys Leu Leu Gln Ala
                 500                 505                 510

 Pro Phe Thr Asp Cys Gly Asp Gly Pro Met Leu Arg Leu Glu Glu
                 515                 520                 525

 Leu Gly Asp Gln Arg His Ala Pro Phe Arg His Ile Cys Arg Leu
                 530                 535                 540

 Cys Tyr Arg Val Leu Arg His Ser Gln Gln Asp Tyr Arg Lys Asn
                 545                 550                 555

 Gln Glu Tyr Ile Ala Lys Gln Phe Gly Phe Met Gln Lys Gln Ile
                 560                 565                 570

 Gly Tyr Asp Val Leu Ala Glu Asp Thr Ile Thr Ala Leu Leu His
                 575                 580                 585

 Asn Asn Arg Lys Leu Leu Glu Lys His Ile Thr Ala Ala Glu Ile
                 590                 595                 600

 Asp Thr Phe Val Ser Leu Val Arg Lys Asn Arg Glu Pro Arg Phe
                 605                 610                 615

 Leu Asp Tyr Leu Ser Asp Leu Cys Val Ser Met Asn Lys Ser Ile
                 620                 625                 630

 Pro Val Thr Gln Glu Leu Ile Cys Lys Ala Val Leu Asn Pro Thr
                 635                 640                 645

 Asn Ala Asp Ile Leu Ile Glu Thr Lys Leu Val Leu Ser Arg Phe
                 650                 655                 660

 Glu Phe Glu Gly Val Ser Ser Thr Gly Glu Asn Ala Leu Glu Ala
                 665                 670                 675

 Gly Glu Asp Glu Glu Glu Val Trp Leu Phe Trp Arg Asp Ser Asn
                 680                 685                 690

 Lys Glu Ile Arg Ser Lys Ser Val Arg Glu Leu Ala Gln Asp Ala
                 695                 700                 705

 Lys Glu Gly Gln Lys Glu Asp Arg Asp Val Leu Ser Tyr Tyr Arg
                 710                 715                 720

 Tyr Gln Leu Asn Leu Phe Ala Arg Met Cys Leu Asp Arg Gln Tyr
                 725                 730                 735

 Leu Ala Ile Asn Glu Ile Ser Gly Gln Leu Asp Val Asp Leu Ile
                 740                 745                 750

 Leu Arg Cys Met Ser Asp Glu Asn Leu Pro Tyr Asp Leu Arg Ala
                 755                 760                 765

 Ser Phe Cys Arg Leu Met Leu His Met His Val Asp Arg Asp Pro
                 770                 775                 780

 Gln Glu Gln Val Thr Pro Val Lys Tyr Ala Arg Leu Trp Ser Glu
                 785                 790                 795

 Ile Pro Ser Glu Ile Ala Ile Asp Asp Tyr Asp Ser Ser Gly Ala
                 800                 805                 810

 Ser Lys Asp Glu Ile Lys Glu Arg Phe Ala Gln Thr Met Glu Phe
                 815                 820                 825

 Val Glu Glu Tyr Leu Arg Asp Val Val Cys Gln Arg Phe Pro Phe
                 830                 835                 840

 Ser Asp Lys Glu Lys Asn Lys Leu Thr Phe Glu Val Val Asn Leu
                 845                 850                 855

 Ala Arg Asn Leu Ile Tyr Phe Gly Phe Tyr Asn Phe Ser Asp Leu
                 860                 865                 870

 Leu Arg Leu Thr Lys Ile Leu Leu Ala Ile Leu Asp Cys Val His
                 875                 880                 885

 Val Thr Thr Ile Phe Pro Ile Ser Lys Met Ala Lys Gly Glu Glu
                 890                 895                 900

 Asn Lys Gly Ser Asn Val Met Arg Ser Ile His Gly Val Gly Glu
                 905                 910                 915

 Leu Met Thr Gln Val Val Leu Arg Gly Gly Gly Phe Leu Pro Met
                 920                 925                 930

 Thr Pro Met Ala Ala Ala Pro Glu Gly Asn Val Lys Gln Ala Glu
                 935                 940                 945

 Pro Glu Lys Glu Asp Ile Met Val Met Asp Thr Lys Leu Lys Ile
                 950                 955                 960

 Ile Glu Ile Leu Gln Phe Ile Leu Asn Val Arg Leu Asp Tyr Arg
                 965                 970                 975

 Ile Ser Cys Leu Leu Cys Ile Phe Lys Arg Glu Phe Asp Glu Ser
                 980                 985                 990

 Asn Ser Gln Thr Ser Glu Thr Ser Ser Gly Asn Ser Ser Gln Glu
                 995                1000                1005

 Gly Pro Ser Asn Val Pro Gly Ala Leu Asp Phe Glu His Ile Glu
                1010                1015                1020

 Glu Gln Ala Glu Gly Ile Phe Gly Gly Ser Glu Glu Asn Thr Pro
                1025                1030                1035

 Leu Asp Leu Asp Asp His Gly Gly Arg Thr Phe Leu Arg Val Leu
                1040                1045                1050

 Leu His Leu Thr Met His Asp Tyr Pro Pro Leu Val Ser Gly Ala
                1055                1060                1065

 Leu Gln Leu Leu Phe Arg His Phe Ser Gln Arg Gln Glu Val Leu
                1070                1075                1080

 Gln Ala Phe Lys Gln Val Gln Leu Leu Val Thr Ser Gln Asp Val
                1085                1090                1095

 Asp Asn Tyr Lys Gln Ile Lys Gln Asp Leu Asp Gln Leu Arg Ser
                1100                1105                1110

 Ile Val Glu Lys Ser Glu Leu Trp Val Tyr Lys Gly Gln Gly Pro
                1115                1120                1125

 Asp Glu Thr Met Asp Gly Ala Ser Gly Glu Asn Glu His Lys Lys
                1130                1135                1140

 Thr Glu Glu Gly Asn Asn Lys Pro Gln Lys His Glu Ser Thr Ser
                1145                1150                1155

 Ser Tyr Asn Tyr Arg Val Val Lys Glu Ile Leu Ile Arg Leu Ser
                1160                1165                1170

 Lys Leu Cys Val Gln Glu Ser Ala Ser Val Arg Lys Ser Arg Lys
                1175                1180                1185

 Gln Gln Gln Arg Leu Leu Arg Asn Met Gly Ala His Ala Val Val
                1190                1195                1200

 Leu Glu Leu Leu Gln Ile Pro Tyr Glu Lys Ala Glu Asp Thr Lys
                1205                1210                1215

 Met Gln Glu Ile Met Arg Leu Ala His Glu Phe Leu Gln Asn Phe
                1220                1225                1230

 Cys Ala Gly Asn Gln Gln Asn Gln Ala Leu Leu His Lys His Ile
                1235                1240                1245

 Asn Leu Phe Leu Asn Pro Gly Ile Leu Glu Ala Val Thr Met Gln
                1250                1255                1260

 His Ile Phe Met Asn Asn Phe Gln Leu Cys Ser Glu Ile Asn Glu
                1265                1270                1275

 Arg Val Val Gln His Phe Val His Cys Ile Glu Thr His Gly Arg
                1280                1285                1290

 Asn Val Gln Tyr Ile Lys Phe Leu Gln Thr Ile Val Lys Ala Glu
                1295                1300                1305

 Gly Lys Phe Ile Lys Lys Cys Gln Asp Met Val Met Ala Glu Leu
                1310                1315                1320

 Val Asn Ser Gly Glu Asp Val Leu Val Phe Tyr Asn Asp Arg Ala
                1325                1330                1335

 Ser Phe Gln Thr Leu Ile Gln Met Met Arg Ser Glu Arg Asp Arg
                1340                1345                1350

 Met Asp Glu Asn Ser Pro Leu Met Tyr His Ile His Leu Val Glu
                1355                1360                1365

 Leu Leu Ala Val Cys Thr Glu Gly Lys Asn Val Tyr Thr Glu Ile
                1370                1375                1380

 Lys Cys Asn Ser Leu Leu Pro Leu Asp Asp Ile Val Arg Val Val
                1385                1390                1395

 Thr His Glu Asp Cys Ile Pro Glu Val Lys Ile Ala Tyr Ile Asn
                1400                1405                1410

 Phe Leu Asn His Cys Tyr Val Asp Thr Glu Val Glu Met Lys Glu
                1415                1420                1425

 Ile Tyr Thr Ser Asn His Met Trp Lys Leu Phe Glu Asn Phe Leu
                1430                1435                1440

 Val Asp Ile Cys Arg Ala Cys Asn Asn Thr Ser Asp Arg Lys His
                1445                1450                1455

 Ala Asp Ser Ile Leu Glu Lys Tyr Val Thr Glu Ile Val Met Ser
                1460                1465                1470

 Ile Val Thr Thr Phe Phe Ser Ser Pro Phe Ser Asp Gln Ser Thr
                1475                1480                1485

 Thr Leu Gln Thr Arg Gln Pro Val Phe Val Gln Leu Leu Gln Gly
                1490                1495                1500

 Val Phe Arg Val Tyr His Cys Asn Trp Leu Met Pro Ser Gln Lys
                1505                1510                1515

 Ala Ser Val Glu Ser Cys Ile Arg Val Leu Ser Asp Val Ala Lys
                1520                1525                1530

 Ser Arg Ala Ile Ala Ile Pro Val Asp Leu Asp Ser Gln Val Asn
                1535                1540                1545

 Asn Leu Phe Leu Lys Ser His Ser Ile Val Gln Lys Thr Ala Met
                1550                1555                1560

 Asn Trp Arg Leu Ser Ala Arg Asn Ala Ala Arg Arg Asp Ser Val
                1565                1570                1575

 Leu Ala Ala Ser Arg Asp Tyr Arg Asn Ile Ile Glu Arg Leu Gln
                1580                1585                1590

 Asp Ile Val Ser Ala Leu Glu Asp Arg Leu Arg Pro Leu Val Gln
                1595                1600                1605

 Ala Glu Leu Ser Val Leu Val Asp Val Leu His Arg Pro Glu Leu
                1610                1615                1620

 Leu Phe Pro Glu Asn Thr Asp Ala Arg Arg Lys Cys Glu Ser Gly
                1625                1630                1635

 Gly Phe Ile Cys Lys Leu Ile Lys His Thr Lys Gln Leu Leu Glu
                1640                1645                1650

 Glu Asn Glu Glu Lys Leu Cys Ile Lys Val Leu Gln Thr Leu Arg
                1655                1660                1665

 Glu Met Met Thr Lys Asp Arg Gly Tyr Gly Glu Lys Gly Glu Ala
                1670                1675                1680

 Leu Arg Gln Val Leu Val Asn Arg Tyr Tyr Gly Asn Val Arg Pro
                1685                1690                1695

 Ser Gly Arg Arg Glu Ser Leu Thr Ser Phe Gly Asn Gly Pro Leu
                1700                1705                1710

 Ser Ala Gly Gly Pro Gly Lys Pro Gly Gly Gly Gly Gly Gly Ser
                1715                1720                1725

 Gly Ser Ser Ser Met Ser Arg Gly Glu Met Ser Leu Ala Glu Val
                1730                1735                1740

 Gln Cys His Leu Asp Lys Glu Gly Ala Ser Asn Leu Val Ile Asp
                1745                1750                1755

 Leu Ile Met Asn Ala Ser Ser Asp Arg Val Phe His Glu Ser Ile
                1760                1765                1770

 Leu Leu Ala Ile Ala Leu Leu Glu Gly Gly Asn Thr Thr Ile Gln
                1775                1780                1785

 His Ser Phe Phe Cys Arg Leu Thr Glu Asp Lys Lys Ser Glu Lys
                1790                1795                1800

 Phe Phe Lys Val Phe Tyr Asp Arg Met Lys Val Ala Gln Gln Glu
                1805                1810                1815

 Ile Lys Ala Thr Val Thr Val Asn Thr Ser Asp Leu Gly Asn Lys
                1820                1825                1830

 Lys Lys Asp Asp Glu Val Asp Arg Asp Ala Pro Ser Arg Lys Lys
                1835                1840                1845

 Ala Lys Glu Pro Thr Thr Gln Ile Thr Glu Glu Val Arg Asp Gln
                1850                1855                1860

 Leu Leu Glu Ala Ser Ala Ala Thr Arg Lys Ala Phe Thr Thr Phe
                1865                1870                1875

 Arg Arg Glu Ala Asp Pro Asp Asp His Tyr Gln Pro Gly Glu Gly
                1880                1885                1890

 Thr Gln Ala Thr Ala Asp Lys Ala Lys Asp Asp Leu Glu Met Ser
                1895                1900                1905

 Ala Val Ile Thr Ile Met Gln Pro Ile Leu Arg Phe Leu Gln Leu
                1910                1915                1920

 Leu Cys Glu Asn His Asn Arg Asp Leu Gln Asn Phe Leu Arg Cys
                1925                1930                1935

 Gln Asn Asn Lys Thr Asn Tyr Asn Leu Val Cys Glu Thr Leu Gln
                1940                1945                1950

 Phe Leu Asp Cys Ile Cys Gly Ser Thr Thr Gly Gly Leu Gly Leu
                1955                1960                1965

 Leu Gly Leu Tyr Ile Asn Glu Lys Asn Val Ala Leu Ile Asn Gln
                1970                1975                1980

 Thr Leu Glu Ser Leu Thr Glu Tyr Cys Gln Gly Pro Cys His Glu
                1985                1990                1995

 Asn Gln Asn Cys Ile Ala Thr His Glu Ser Asn Gly Ile Asp Ile
                2000                2005                2010

 Ile Thr Ala Leu Ile Leu Asn Asp Ile Asn Pro Leu Gly Lys Lys
                2015                2020                2025

 Arg Met Asp Leu Val Leu Glu Leu Lys Asn Asn Ala Ser Lys Leu
                2030                2035                2040

 Leu Leu Ala Ile Met Glu Ser Arg His Asp Ser Glu Asn Ala Glu
                2045                2050                2055

 Arg Ile Leu Tyr Asn Met Arg Pro Lys Glu Leu Val Glu Val Ile
                2060                2065                2070

 Lys Lys Ala Tyr Met Gln Gly Glu Val Glu Phe Glu Asp Gly Glu
                2075                2080                2085

 Asn Gly Glu Asp Gly Ala Ala Ser Pro Arg Asn Val Gly His Asn
                2090                2095                2100

 Ile Tyr Ile Leu Ala His Gln Leu Ala Arg His Asn Lys Glu Leu
                2105                2110                2115

 Gln Ser Met Leu Lys Pro Gly Gly Gln Val Asp Gly Asp Glu Ala
                2120                2125                2130

 Leu Glu Phe Tyr Ala Lys His Thr Ala Gln Ile Glu Ile Val Arg
                2135                2140                2145

 Leu Asp Arg Thr Met Glu Gln Ile Val Phe Pro Val Pro Ser Ile
                2150                2155                2160

 Cys Glu Phe Leu Thr Lys Glu Ser Lys Leu Arg Ile Tyr Tyr Thr
                2165                2170                2175

 Thr Glu Arg Asp Glu Gln Gly Ser Lys Ile Asn Asp Phe Phe Leu
                2180                2185                2190

 Arg Ser Glu Asp Leu Phe Asn Glu Met Asn Trp Gln Lys Lys Leu
                2195                2200                2205

 Arg Ala Gln Pro Val Leu Tyr Trp Cys Ala Arg Asn Met Ser Phe
                2210                2215                2220

 Trp Ser Ser Ile Ser Phe Asn Leu Ala Val Leu Met Asn Leu Leu
                2225                2230                2235

 Val Ala Phe Phe Tyr Pro Phe Lys Gly Val Arg Gly Gly Thr Leu
                2240                2245                2250

 Glu Pro His Trp Ser Gly Leu Leu Trp Thr Ala Met Leu Ile Ser
                2255                2260                2265

 Leu Ala Ile Val Ile Ala Leu Pro Lys Pro His Gly Ile Arg Ala
                2270                2275                2280

 Leu Ile Ala Ser Thr Ile Leu Arg Leu Ile Phe Ser Val Gly Leu
                2285                2290                2295

 Gln Pro Thr Leu Phe Leu Leu Gly Ala Phe Asn Val Cys Asn Lys
                2300                2305                2310

 Ile Ile Phe Leu Met Ser Phe Val Gly Asn Cys Gly Thr Phe Thr
                2315                2320                2325

 Arg Gly Tyr Arg Ala Met Val Leu Asp Val Glu Phe Leu Tyr His
                2330                2335                2340

 Leu Leu Tyr Leu Val Ile Cys Ala Met Gly Leu Phe Val His Glu
                2345                2350                2355

 Phe Phe Tyr Ser Leu Leu Leu Phe Asp Leu Val Tyr Arg Glu Glu
                2360                2365                2370

 Thr Leu Leu Asn Val Ile Lys Ser Val Thr Arg Asn Gly Arg Ser
                2375                2380                2385

 Ile Ile Leu Thr Ala Val Leu Ala Leu Ile Leu Val Tyr Leu Phe
                2390                2395                2400

 Ser Ile Val Gly Tyr Leu Phe Phe Lys Asp Asp Phe Ile Leu Glu
                2405                2410                2415

 Val Asp Arg Leu Pro Asn Glu Thr Ala Val Pro Glu Thr Gly Glu
                2420                2425                2430

 Ser Leu Ala Ser Glu Phe Leu Phe Ser Asp Val Cys Arg Val Glu
                2435                2440                2445

 Ser Gly Glu Asn Cys Ser Ser Pro Ala Pro Arg Glu Glu Leu Val
                2450                2455                2460

 Pro Ala Glu Glu Thr Glu Gln Asp Lys Glu His Thr Cys Glu Thr
                2465                2470                2475

 Leu Leu Met Cys Ile Val Thr Val Leu Ser His Gly Leu Arg Ser
                2480                2485                2490

 Gly Gly Gly Val Gly Asp Val Leu Arg Lys Pro Ser Lys Glu Glu
                2495                2500                2505

 Pro Leu Phe Ala Ala Arg Val Ile Tyr Asp Leu Leu Phe Phe Phe
                2510                2515                2520

 Met Val Ile Ile Ile Val Leu Asn Leu Ile Phe Gly Val Ile Ile
                2525                2530                2535

 Asp Thr Phe Ala Asp Leu Arg Ser Glu Lys Gln Lys Lys Glu Glu
                2540                2545                2550

 Ile Leu Lys Thr Thr Cys Phe Ile Cys Gly Leu Glu Arg Asp Lys
                2555                2560                2565

 Phe Asp Asn Lys Thr Val Thr Phe Glu Glu His Ile Lys Glu Glu
                2570                2575                2580

 His Asn Met Trp His Tyr Leu Cys Phe Ile Val Leu Val Lys Val
                2585                2590                2595

 Lys Asp Ser Thr Glu Tyr Thr Gly Pro Glu Ser Tyr Val Ala Glu
                2600                2605                2610

 Met Ile Lys Glu Arg Asn Leu Asp Trp Phe Pro Arg Met Arg Ala
                2615                2620                2625

 Met Ser Leu Val Ser Ser Asp Ser Glu Gly Glu Gln Asn Glu Leu
                2630                2635                2640

 Arg Asn Leu Gln Glu Lys Leu Glu Ser Thr Met Lys Leu Val Thr
                2645                2650                2655

 Asn Leu Ser Gly Gln Leu Ser Glu Leu Lys Asp Gln Met Thr Glu
                2660                2665                2670

 Gln Arg Lys Gln Lys Gln Arg Ile Gly Leu Leu Gly His Pro Pro
                2675                2680                2685

 His Met Asn Val Asn Pro Gln Gln Pro Ala
                2690                2695

<210> 5469
<211> 3254
<212> DNA
<213> Homo sapien

<400> 5469
 agagttgcac tgagtgtggc tgaagcagcg aggcgggagt ggaggtgcgc 50

 ggagtcaggc agacagacag acacagccag ccagccaggt cggcagtata 100

 gtccgaactg caaatcttat tttcttttca ccttctctct aactgcccag 150

 agctagcgcc tgtggctccc gggctggtgg ttcgggagtg tccagagagc 200

 cttgtctcca gccggccccg ggaggagagc cctgctgccc aggcgctgtt 250

 gacagcggcg gaaagcagcg gtaccccacg cgcccgccgg gggacgtcgg 300

 cgagcggctg cagcagcaaa gaactttccc ggcggggagg accggagaca 350

 agtggcagag tcccggagcg aacttttgca agcctttcct gcgtcttagg 400

 cttctccacg gcggtaaaga ccagaaggcg gcggagagcc acgcaagaga 450

 agaaggacgt gcgctcagct tcgctcgcac cggttgttga acttgggcga 500

 gcgcgagccg cggctgccgg gcgccccctc cccctagcag cggaggaggg 550

 gacaagtcgt cggagtccgg gcggccaaga cccgccgccg gccggccact 600

 gcagggtccg cactgatccg ctccgcgggg agagccgctg ctctgggaag 650

 tgagttcgcc tgcggactcc gaggaaccgc tgcgcccgaa gagcgctcag 700

 tgagtgaccg cgacttttca aagccgggta gcgcgcgcga gtcgacaagt 750

 aagagtgcgg gaggcatctt aattaaccct gcgctccctg gagcgagctg 800

 gtgaggaggg cgcagcgggg acgacagcca gcgggtgcgt gcgctcttag 850

 agaaactttc cctgtcaaag gctccggggg gcgcgggtgt cccccgcttg 900

 ccagagccct gttgcggccc cgaaacttgt gcgcgcacgc caaactaacc 950

 tcacgtgaag tgacggactg ttctatgact gcaaagatgg aaacgacctt 1000

 ctatgacgat gccctcaacg cctcgttcct cccgtccgag agcggacctt 1050

 atggctacag taaccccaag atcctgaaac agagcatgac cctgaacctg 1100

 gccgacccag tggggagcct gaagccgcac ctccgcgcca agaactcgga 1150

 cctcctcacc tcgcccgacg tggggctgct caagctggcg tcgcccgagc 1200

 tggagcgcct gataatccag tccagcaacg ggcacatcac caccacgccg 1250

 acccccaccc agttcctgtg ccccaagaac gtgacagatg agcaggaggg 1300

 gttcgccgag ggcttcgtgc gcgccctggc cgaactgcac agccagaaca 1350

 cgctgcccag cgtcacgtcg gcggcgcagc cggtcaacgg ggcaggcatg 1400

 gtggctcccg cggtagcctc ggtggcaggg ggcagcggca gcggcggctt 1450

 cagcgccagc ctgcacagcg agccgccggt ctacgcaaac ctcagcaact 1500

 tcaacccagg cgcgctgagc agcggcggcg gggcgccctc ctacggcgcg 1550

 gccggcctgg cctttcccgc gcaaccccag cagcagcagc agccgccgca 1600

 ccacctgccc cagcagatgc ccgtgcagca cccgcggctg caggccctga 1650

 aggaggagcc tcagacagtg cccgagatgc ccggcgagac accgcccctg 1700

 tcccccatcg acatggagtc ccaggagcgg atcaaggcgg agaggaagcg 1750

 catgaggaac cgcatcgctg cctccaagtg ccgaaaaagg aagctggaga 1800

 gaatcgcccg gctggaggaa aaagtgaaaa ccttgaaagc tcagaactcg 1850

 gagctggcgt ccacggccaa catgctcagg gaacaggtgg cacagcttaa 1900

 acagaaagtc atgaaccacg ttaacagtgg gtgccaactc atgctaacgc 1950

 agcagttgca aacattttga agagagaccg tcgggggctg aggggcaacg 2000

 aagaaaaaaa ataacacaga gagacagact tgagaacttg acaagttgcg 2050

 acggagagaa aaaagaagtg tccgagaact aaagccaagg gtatccaagt 2100

 tggactgggt tcggtctgac ggcgccccca gtgtgcacga gtgggaagga 2150

 cttggtcgcg ccctcccttg gcgtggagcc agggagcggc cgcctgcggg 2200

 ctgccccgct ttgcggacgg gctgtccccg cgcgaacgga acgttggact 2250

 ttcgttaaca ttgaccaaga actgcatgga cctaacattc gatctcattc 2300

 agtattaaag gggggagggg gagggggtta caaactgcaa tagagactgt 2350

 agattgcttc tgtagtactc cttaagaaca caaagcgggg ggagggttgg 2400

 ggaggggcgg caggagggag gtttgtgaga gcgaggctga gcctacagat 2450

 gaactctttc tggcctgctt tcgttaactg tgtatgtaca tatatatatt 2500

 ttttaatttg attaaagctg attactgtca ataaacagct tcatgccttt 2550

 gtaagttatt tcttgtttgt ttgtttgggt atcctgccca gtgttgtttg 2600

 taaataagag atttggagca ctctgagttt accatttgta ataaagtata 2650

 taattttttt atgttttgtt tctgaaaatt ccagaaagga tatttaagaa 2700

 aatacaataa actattggaa agtactcccc taacctcttt tctgcatcat 2750

 ctgtagatcc tagtctatct aggtggagtt gaaagagtta agaatgctcg 2800

 ataaaatcac tctcagtgct tcttactatt aagcagtaaa aactgttctc 2850

 tattagactt agaaataaat gtacctgatg tacctgatgc tatgtcaggc 2900

 ttcatactcc acgctccccc agcgtatcta tatggaattg cttaccaaag 2950

 gctagtgcga tgtttcagga ggctggagga aggggggttg cagtggagag 3000

 ggacagccca ctgagaagtc aaacatttca aagtttggat tgcatcaagt 3050

 ggcatgtgct gtgaccattt ataatgttag aaattttaca ataggtgctt 3100

 attctcaaag caggaattgg tggcagattt tacaaaagat gtatccttcc 3150

 aatttggaat cttctctttg acaattccta gataaaaaga tggcctttgt 3200

 cttatgaata tttataacag cattctgtca caataaatgt attcaaatac 3250

 caat 3254

<210> 5470
<211> 331
<212> PRT
<213> Homo sapien

<400> 5470
 Met Thr Ala Lys Met Glu Thr Thr Phe Tyr Asp Asp Ala Leu Asn
   1               5                  10                  15

 Ala Ser Phe Leu Pro Ser Glu Ser Gly Pro Tyr Gly Tyr Ser Asn
                  20                  25                  30

 Pro Lys Ile Leu Lys Gln Ser Met Thr Leu Asn Leu Ala Asp Pro
                  35                  40                  45

 Val Gly Ser Leu Lys Pro His Leu Arg Ala Lys Asn Ser Asp Leu
                  50                  55                  60

 Leu Thr Ser Pro Asp Val Gly Leu Leu Lys Leu Ala Ser Pro Glu
                  65                  70                  75

 Leu Glu Arg Leu Ile Ile Gln Ser Ser Asn Gly His Ile Thr Thr
                  80                  85                  90

 Thr Pro Thr Pro Thr Gln Phe Leu Cys Pro Lys Asn Val Thr Asp
                  95                 100                 105

 Glu Gln Glu Gly Phe Ala Glu Gly Phe Val Arg Ala Leu Ala Glu
                 110                 115                 120

 Leu His Ser Gln Asn Thr Leu Pro Ser Val Thr Ser Ala Ala Gln
                 125                 130                 135

 Pro Val Asn Gly Ala Gly Met Val Ala Pro Ala Val Ala Ser Val
                 140                 145                 150

 Ala Gly Gly Ser Gly Ser Gly Gly Phe Ser Ala Ser Leu His Ser
                 155                 160                 165

 Glu Pro Pro Val Tyr Ala Asn Leu Ser Asn Phe Asn Pro Gly Ala
                 170                 175                 180

 Leu Ser Ser Gly Gly Gly Ala Pro Ser Tyr Gly Ala Ala Gly Leu
                 185                 190                 195

 Ala Phe Pro Ala Gln Pro Gln Gln Gln Gln Gln Pro Pro His His
                 200                 205                 210

 Leu Pro Gln Gln Met Pro Val Gln His Pro Arg Leu Gln Ala Leu
                 215                 220                 225

 Lys Glu Glu Pro Gln Thr Val Pro Glu Met Pro Gly Glu Thr Pro
                 230                 235                 240

 Pro Leu Ser Pro Ile Asp Met Glu Ser Gln Glu Arg Ile Lys Ala
                 245                 250                 255

 Glu Arg Lys Arg Met Arg Asn Arg Ile Ala Ala Ser Lys Cys Arg
                 260                 265                 270

 Lys Arg Lys Leu Glu Arg Ile Ala Arg Leu Glu Glu Lys Val Lys
                 275                 280                 285

 Thr Leu Lys Ala Gln Asn Ser Glu Leu Ala Ser Thr Ala Asn Met
                 290                 295                 300

 Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Met Asn His
                 305                 310                 315

 Val Asn Ser Gly Cys Gln Leu Met Leu Thr Gln Gln Leu Gln Thr
                 320                 325                 330

 Phe


<210> 5471
<211> 1797
<212> DNA
<213> Homo sapien

<400> 5471
 ccagcaggga gctgggagct gggggaaacg acgccaggaa agctatcgcg 50

 ccagagaggg cgacgggggc tcgggaagcc tgacagggct tttgcgcaca 100

 gctgccggct ggctgctacc cgcccgcgcc agcccccgag aacgcgcgac 150

 caggcaccca gtccggtcac cgcagcggag agctcgccgc tcgctgcagc 200

 gaggcccgga gcggccccgc agggaccctc cccagaccgc ctgggccgcc 250

 cggatgtgca ctaaaatgga acagcccttc taccacgacg actcatacac 300

 agctacggga tacggccggg cccctggtgg cctctctcta cacgactaca 350

 aactcctgaa accgagcctg gcggtcaacc tggccgaccc ctaccggagt 400

 ctcaaagcgc ctggggctcg cggacccggc ccagagggcg gcggtggcgg 450

 cagctacttt tctggtcagg gctcggacac cggcgcgtct ctcaagctcg 500

 cctcttcgga gctggaacgc ctgattgtcc ccaacagcaa cggcgtgatc 550

 acgacgacgc ctacaccccc gggacagtac ttttaccccc gcgggggtgg 600

 cagcggtgga ggtgcagggg gcgcaggggg cggcgtcacc gaggagcagg 650

 agggcttcgc cgacggcttt gtcaaagccc tggacgatct gcacaagatg 700

 aaccacgtga caccccccaa cgtgtccctg ggcgctaccg gggggccccc 750

 ggctgggccc gggggcgtct acgccggccc ggagccacct cccgtttaca 800

 ccaacctcag cagctactcc ccagcctctg cgtcctcggg aggcgccggg 850

 gctgccgtcg ggaccgggag ctcgtacccg acgaccacca tcagctacct 900

 cccacacgcg ccgcccttcg ccggtggcca cccggcgcag ctgggcttgg 950

 gccgcggcgc ctccaccttc aaggaggaac cgcagaccgt gccggaggcg 1000

 cgcagccggg acgccacgcc gccggtgtcc cccatcaaca tggaagacca 1050

 agagcgcatc aaagtggagc gcaagcggct gcggaaccgg ctggcggcca 1100

 ccaagtgccg gaagcggaag ctggagcgca tcgcgcgcct ggaggacaag 1150

 gtgaagacgc tcaaggccga gaacgcgggg ctgtcgagta ccgccggcct 1200

 cctccgggag caggtggccc agctcaaaca gaaggtcatg acccacgtca 1250

 gcaacggctg tcagctgctg cttggggtca agggacacgc cttctgaacg 1300

 tcccctgccc ctttacggac accccctcgc ttggacggct gggcacacgc 1350

 ctcccactgg ggtccaggga gcaggcggtg ggcacccacc ctgggaccta 1400

 ggggcgccgc aaaccacact ggactccggc ccccctaccc tgcgcccagt 1450

 ccttccacct cgacgtttac aagccccccc ttccactttt ttttgtatgt 1500

 tttttttctg ctggaaacag actcgattca tattgaatat aatatatttg 1550

 tgtatttaac agggagggga agagggggcg atcgcggcgg agctggcccc 1600

 gccgcctggt actcaagccc gcggggacat tgggaagggg acccccgccc 1650

 cctgccctcc cctctctgca ccgtactgtg gaaaagaaac acgcacttag 1700

 tctctaaaga gtttatttta agacgtgttt gtgtttgtgt gtgtttgttc 1750

 tttttattga atctatttaa gtaaaaaaaa aattggttct ttattaa 1797

<210> 5472
<211> 347
<212> PRT
<213> Homo sapien

<400> 5472
 Met Cys Thr Lys Met Glu Gln Pro Phe Tyr His Asp Asp Ser Tyr
   1               5                  10                  15

 Thr Ala Thr Gly Tyr Gly Arg Ala Pro Gly Gly Leu Ser Leu His
                  20                  25                  30

 Asp Tyr Lys Leu Leu Lys Pro Ser Leu Ala Val Asn Leu Ala Asp
                  35                  40                  45

 Pro Tyr Arg Ser Leu Lys Ala Pro Gly Ala Arg Gly Pro Gly Pro
                  50                  55                  60

 Glu Gly Gly Gly Gly Gly Ser Tyr Phe Ser Gly Gln Gly Ser Asp
                  65                  70                  75

 Thr Gly Ala Ser Leu Lys Leu Ala Ser Ser Glu Leu Glu Arg Leu
                  80                  85                  90

 Ile Val Pro Asn Ser Asn Gly Val Ile Thr Thr Thr Pro Thr Pro
                  95                 100                 105

 Pro Gly Gln Tyr Phe Tyr Pro Arg Gly Gly Gly Ser Gly Gly Gly
                 110                 115                 120

 Ala Gly Gly Ala Gly Gly Gly Val Thr Glu Glu Gln Glu Gly Phe
                 125                 130                 135

 Ala Asp Gly Phe Val Lys Ala Leu Asp Asp Leu His Lys Met Asn
                 140                 145                 150

 His Val Thr Pro Pro Asn Val Ser Leu Gly Ala Thr Gly Gly Pro
                 155                 160                 165

 Pro Ala Gly Pro Gly Gly Val Tyr Ala Gly Pro Glu Pro Pro Pro
                 170                 175                 180

 Val Tyr Thr Asn Leu Ser Ser Tyr Ser Pro Ala Ser Ala Ser Ser
                 185                 190                 195

 Gly Gly Ala Gly Ala Ala Val Gly Thr Gly Ser Ser Tyr Pro Thr
                 200                 205                 210

 Thr Thr Ile Ser Tyr Leu Pro His Ala Pro Pro Phe Ala Gly Gly
                 215                 220                 225

 His Pro Ala Gln Leu Gly Leu Gly Arg Gly Ala Ser Thr Phe Lys
                 230                 235                 240

 Glu Glu Pro Gln Thr Val Pro Glu Ala Arg Ser Arg Asp Ala Thr
                 245                 250                 255

 Pro Pro Val Ser Pro Ile Asn Met Glu Asp Gln Glu Arg Ile Lys
                 260                 265                 270

 Val Glu Arg Lys Arg Leu Arg Asn Arg Leu Ala Ala Thr Lys Cys
                 275                 280                 285

 Arg Lys Arg Lys Leu Glu Arg Ile Ala Arg Leu Glu Asp Lys Val
                 290                 295                 300

 Lys Thr Leu Lys Ala Glu Asn Ala Gly Leu Ser Ser Thr Ala Gly
                 305                 310                 315

 Leu Leu Arg Glu Gln Val Ala Gln Leu Lys Gln Lys Val Met Thr
                 320                 325                 330

 His Val Ser Asn Gly Cys Gln Leu Leu Leu Gly Val Lys Gly His
                 335                 340                 345

 Ala Phe


<210> 5473
<211> 2240
<212> DNA
<213> Homo sapien

<400> 5473
 gtccttcggt gtctgggtgt ggtgagtaga ggtgtgtgtc acaaagtaca 50

 gaccattgtg tgtgacaaag cccatcgtgt gtctgtgtgt gtctttatcc 100

 acgtggatgg acgtctcttt cttgctctgc cccaagacac accctagccc 150

 ctccttattc tcaaaagggg gagctgggga gcctccccct accctggggc 200

 ctcccctgcc cctccccgcc ctgcctggcc gtcaccactc cccagagggc 250

 acagggctct gctgtgcctc agagcaaaag tcccagagcc agcagagcag 300

 gctgacgacc tgcaagccac agtggctgcc ctgtgcgtgc tgcgaggtgg 350

 gggaccctgg gcaggaagct ggctgagccc caagaccccg ggggccatgg 400

 gcggggatct ggtgcttggc ctgggggcct tgagacgccg aaagcgcttg 450

 ctggagcagg agaagtctct ggccggctgg gcactggtgc tggcaggaac 500

 tggcattgga ctcatggtgc tgcatgcaga gatgctgtgg ttcggggggt 550

 gctcgtgggc gctctacctg ttcctggtta aatgcacgat cagcatttcc 600

 accttcttac tcctctgcct catcgtggcc tttcatgcca aagaggtcca 650

 gctgttcatg accgacaacg ggctgcggga ctggcgcgtg gcgctgaccg 700

 ggcggcaggc ggcgcagatc gtgctggagc tggtggtgtg tgggctgcac 750

 ccggcgcccg tgcggggccc gccgtgcgtg caggatttag gggcgccgct 800

 gacctccccg cagccctggc cgggattcct gggccaaggg gaagcgctgc 850

 tgtccctggc catgctgctg cgtctctacc tggtgccccg cgccgtgctc 900

 ctgcgcagcg gcgtcctgct caacgcttcc taccgcagca tcggcgctct 950

 caatcaagtc cgcttccgcc actggttcgt ggccaagctt tacatgaaca 1000

 cgcaccctgg ccgcctgctg ctcggcctca cgcttggcct ctggctgacc 1050

 accgcctggg tgctgtccgt ggccgagagg caggctgtta atgccactgg 1100

 gcacctttca gacacacttt ggctgatccc catcacattc ctgaccatcg 1150

 gctatggtga cgtggtgccg ggcaccatgt ggggcaagat cgtctgcctg 1200

 tgcactggag tcatgggtgt ctgctgcaca gccctgctgg tggccgtggt 1250

 ggcccggaag ctggagttta acaaggcaga gaagcacgtg cacaacttca 1300

 tgatggatat ccagtatacc aaagagatga aggagtccgc tgcccgagtg 1350

 ctacaagaag cctggatgtt ctacaaacat actcgcagga aggagtctca 1400

 tgctgcccgc aggcatcagc gcaagctgct ggccgccatc aacgcgttcc 1450

 gccaggtgcg gctgaaacac cggaagctcc gggaacaagt gaactccatg 1500

 gtggacatct ccaagatgca catgatcctg tatgacctgc agcagaatct 1550

 gagcagctca caccgggccc tggagaaaca gattgacacg ctggcgggga 1600

 agctggatgc cctgactgag ctgcttagca ctgccctggg gccgaggcag 1650

 cttccagaac ccagccagca gtccaagtag ctggacccac gaggaggaac 1700

 caggctactt tccccagtac tgaggtggtg gacatcgtct ctgccactcc 1750

 tgacccagcc ctgaacaaag cacctcaagt gcaaggacca aagggggccc 1800

 tggcttggag tgggttggct tgctgatggc tgctggaggg gacgctggct 1850

 aaagtgggta ggccttggcc cacctgaggc cccaggtggg aacatggtca 1900

 cccccactct gcataccctc atcaaaaaca ctctcactat gctgctatgg 1950

 acgacctcca gctctcagtt acaagtgcag gcgactggag gcaggactcc 2000

 tgggtccctg ggaaagaggg tactaggggc ccggatccag gattctggga 2050

 ggcttcagtt accgctggcc gagctgaaga actgggtatg aggctggggc 2100

 ggggctggag gtggcgcccc ctggtgggac aacaaagagg acaccatttt 2150

 tccagagctg cagagagcac ctggtgggga ggaagaagtg taactcacca 2200

 gcctctgctc ttatctttgt aataaatgtt aaagccagaa 2240

<210> 5474
<211> 427
<212> PRT
<213> Homo sapien

<400> 5474
 Met Gly Gly Asp Leu Val Leu Gly Leu Gly Ala Leu Arg Arg Arg
   1               5                  10                  15

 Lys Arg Leu Leu Glu Gln Glu Lys Ser Leu Ala Gly Trp Ala Leu
                  20                  25                  30

 Val Leu Ala Gly Thr Gly Ile Gly Leu Met Val Leu His Ala Glu
                  35                  40                  45

 Met Leu Trp Phe Gly Gly Cys Ser Trp Ala Leu Tyr Leu Phe Leu
                  50                  55                  60

 Val Lys Cys Thr Ile Ser Ile Ser Thr Phe Leu Leu Leu Cys Leu
                  65                  70                  75

 Ile Val Ala Phe His Ala Lys Glu Val Gln Leu Phe Met Thr Asp
                  80                  85                  90

 Asn Gly Leu Arg Asp Trp Arg Val Ala Leu Thr Gly Arg Gln Ala
                  95                 100                 105

 Ala Gln Ile Val Leu Glu Leu Val Val Cys Gly Leu His Pro Ala
                 110                 115                 120

 Pro Val Arg Gly Pro Pro Cys Val Gln Asp Leu Gly Ala Pro Leu
                 125                 130                 135

 Thr Ser Pro Gln Pro Trp Pro Gly Phe Leu Gly Gln Gly Glu Ala
                 140                 145                 150

 Leu Leu Ser Leu Ala Met Leu Leu Arg Leu Tyr Leu Val Pro Arg
                 155                 160                 165

 Ala Val Leu Leu Arg Ser Gly Val Leu Leu Asn Ala Ser Tyr Arg
                 170                 175                 180

 Ser Ile Gly Ala Leu Asn Gln Val Arg Phe Arg His Trp Phe Val
                 185                 190                 195

 Ala Lys Leu Tyr Met Asn Thr His Pro Gly Arg Leu Leu Leu Gly
                 200                 205                 210

 Leu Thr Leu Gly Leu Trp Leu Thr Thr Ala Trp Val Leu Ser Val
                 215                 220                 225

 Ala Glu Arg Gln Ala Val Asn Ala Thr Gly His Leu Ser Asp Thr
                 230                 235                 240

 Leu Trp Leu Ile Pro Ile Thr Phe Leu Thr Ile Gly Tyr Gly Asp
                 245                 250                 255

 Val Val Pro Gly Thr Met Trp Gly Lys Ile Val Cys Leu Cys Thr
                 260                 265                 270

 Gly Val Met Gly Val Cys Cys Thr Ala Leu Leu Val Ala Val Val
                 275                 280                 285

 Ala Arg Lys Leu Glu Phe Asn Lys Ala Glu Lys His Val His Asn
                 290                 295                 300

 Phe Met Met Asp Ile Gln Tyr Thr Lys Glu Met Lys Glu Ser Ala
                 305                 310                 315

 Ala Arg Val Leu Gln Glu Ala Trp Met Phe Tyr Lys His Thr Arg
                 320                 325                 330

 Arg Lys Glu Ser His Ala Ala Arg Arg His Gln Arg Lys Leu Leu
                 335                 340                 345

 Ala Ala Ile Asn Ala Phe Arg Gln Val Arg Leu Lys His Arg Lys
                 350                 355                 360

 Leu Arg Glu Gln Val Asn Ser Met Val Asp Ile Ser Lys Met His
                 365                 370                 375

 Met Ile Leu Tyr Asp Leu Gln Gln Asn Leu Ser Ser Ser His Arg
                 380                 385                 390

 Ala Leu Glu Lys Gln Ile Asp Thr Leu Ala Gly Lys Leu Asp Ala
                 395                 400                 405

 Leu Thr Glu Leu Leu Ser Thr Ala Leu Gly Pro Arg Gln Leu Pro
                 410                 415                 420

 Glu Pro Ser Gln Gln Ser Lys
                 425

<210> 5475
<211> 738
<212> DNA
<213> Homo sapien

<400> 5475
 aaagcagaat tgagagtttg ttcttacaca caagtttaat gccaccttcc 50

 tctgtctgcc atggaccaac aagcaatata tgctgagtta aacttaccca 100

 cagactcagg cccagaaagt tcttcacctt catctcttcc tcgggatgtc 150

 tgtcagggtt caccttggca tcaatttgcc ctgaaactta gctgtgctgg 200

 gattattctc cttgtcttgg ttgttactgg gttgagtgtt tcagtgacat 250

 ccttaataca gaaatcatca atagaaaaat gcagtgtgga cattcaacag 300

 agcaggaata aaacaacaga gagaccgggt ctcttaaact gcccaatata 350

 ttggcagcaa ctccgagaga aatgcttgtt attttctcac actgtcaacc 400

 cttggaataa cagtctagct gattgttcca ccaaagaatc cagcctgctg 450

 cttattcgag ataaggatga attgatacac acacagaacc tgatacgtga 500

 caaagcaatt ctgttttgga ttggattaaa tttttcatta tcagaaaaga 550

 actggaagtg gataaacggc tcttttttaa attctaatga cttagaaatt 600

 agaggtgatg ctaaagaaaa cagctgtatt tccatctcac agacatctgt 650

 gtattctgag tactgtagta cagaaatcag atggatctgc caaaaagaac 700

 taacacctgt gagaaataaa gtgtatcctg actcttga 738

<210> 5476
<211> 225
<212> PRT
<213> Homo sapien

<400> 5476
 Met Asp Gln Gln Ala Ile Tyr Ala Glu Leu Asn Leu Pro Thr Asp
   1               5                  10                  15

 Ser Gly Pro Glu Ser Ser Ser Pro Ser Ser Leu Pro Arg Asp Val
                  20                  25                  30

 Cys Gln Gly Ser Pro Trp His Gln Phe Ala Leu Lys Leu Ser Cys
                  35                  40                  45

 Ala Gly Ile Ile Leu Leu Val Leu Val Val Thr Gly Leu Ser Val
                  50                  55                  60

 Ser Val Thr Ser Leu Ile Gln Lys Ser Ser Ile Glu Lys Cys Ser
                  65                  70                  75

 Val Asp Ile Gln Gln Ser Arg Asn Lys Thr Thr Glu Arg Pro Gly
                  80                  85                  90

 Leu Leu Asn Cys Pro Ile Tyr Trp Gln Gln Leu Arg Glu Lys Cys
                  95                 100                 105

 Leu Leu Phe Ser His Thr Val Asn Pro Trp Asn Asn Ser Leu Ala
                 110                 115                 120

 Asp Cys Ser Thr Lys Glu Ser Ser Leu Leu Leu Ile Arg Asp Lys
                 125                 130                 135

 Asp Glu Leu Ile His Thr Gln Asn Leu Ile Arg Asp Lys Ala Ile
                 140                 145                 150

 Leu Phe Trp Ile Gly Leu Asn Phe Ser Leu Ser Glu Lys Asn Trp
                 155                 160                 165

 Lys Trp Ile Asn Gly Ser Phe Leu Asn Ser Asn Asp Leu Glu Ile
                 170                 175                 180

 Arg Gly Asp Ala Lys Glu Asn Ser Cys Ile Ser Ile Ser Gln Thr
                 185                 190                 195

 Ser Val Tyr Ser Glu Tyr Cys Ser Thr Glu Ile Arg Trp Ile Cys
                 200                 205                 210

 Gln Lys Glu Leu Thr Pro Val Arg Asn Lys Val Tyr Pro Asp Ser
                 215                 220                 225

<210> 5477
<211> 1261
<212> DNA
<213> Homo sapien

<400> 5477
 gcagttatca tagagcacag tccctcacat cacacagctg cagagatgag 50

 taaacaaaga ggaaccttct cagaagtgag tctggcccag gacccaaagc 100

 ggcagcaaag gaaacctaaa ggcaataaaa gctccatttc aggaaccgaa 150

 caggaaatat tccaagtaga attaaatctt caaaatcctt ccctgaatca 200

 tcaagggatt gataaaatat atgactgcca aggtttactg ccacctccag 250

 agaagctcac tgccgaggtc ctaggaatca tttgcattgt cctgatggcc 300

 actgtgttaa aaacaatagt tcttattcct ttcctggagc agaacaattc 350

 ttccccgaat acaagaacgc agaaagcacg tcattgtggc cattgtcctg 400

 aggagtggat tacatattcc aacagttgtt attacattgg taaggaaaga 450

 agaacttggg aagagagttt gctggcctgt acttcgaaga actccagtct 500

 gctttctata gataatgaag aagaaataaa atttctggcc agcattttac 550

 cttcctcatg gattggtgtg tttcgtaaca gcagtcatca tccatgggtg 600

 acaataaatg gtttggcttt caaacataag ataaaagact cagataatgc 650

 tgaacttaac tgtgcagtgc tacaagtaaa tcgacttaaa tcagcccagt 700

 gtggatcttc aatgatatat cattgtaagc ataagcttta gaagtaaagc 750

 atttgcgttt acagtgcatc agatacattt tatatttctt aaaatagaaa 800

 tattatgatt gcataaatct gaaaatgaat tatgttattt gctctaatac 850

 aaaaattcta aatcaattat tgaaatagga tgcacacaat tactaaagta 900

 cagacatcct agcatttgtg tcgggctcat tttgctcaac atggtatttg 950

 tggttttcag cctttctaaa agttgcatgt tatgtgagtc agcttatagg 1000

 aagtaccaag aacagtcaaa cccatggaga cagaaagtag aatagtggtt 1050

 gccaatgtct cagggaggtt gaaataggag atgaccacta attgatagaa 1100

 cgtttctttg tgtcgtgatg aaaactttct aaatttcagt aatggtgatg 1150

 gttgtaactt tgcgaatata ctaaacatca ttgattttta atcattttaa 1200

 gtgcatgaaa tgtatgcttt gtacatgaca cttcaataaa gctatccaga 1250

 aaaaaaaaaa a 1261

<210> 5478
<211> 231
<212> PRT
<213> Homo sapien

<400> 5478
 Met Ser Lys Gln Arg Gly Thr Phe Ser Glu Val Ser Leu Ala Gln
   1               5                  10                  15

 Asp Pro Lys Arg Gln Gln Arg Lys Pro Lys Gly Asn Lys Ser Ser
                  20                  25                  30

 Ile Ser Gly Thr Glu Gln Glu Ile Phe Gln Val Glu Leu Asn Leu
                  35                  40                  45

 Gln Asn Pro Ser Leu Asn His Gln Gly Ile Asp Lys Ile Tyr Asp
                  50                  55                  60

 Cys Gln Gly Leu Leu Pro Pro Pro Glu Lys Leu Thr Ala Glu Val
                  65                  70                  75

 Leu Gly Ile Ile Cys Ile Val Leu Met Ala Thr Val Leu Lys Thr
                  80                  85                  90

 Ile Val Leu Ile Pro Phe Leu Glu Gln Asn Asn Ser Ser Pro Asn
                  95                 100                 105

 Thr Arg Thr Gln Lys Ala Arg His Cys Gly His Cys Pro Glu Glu
                 110                 115                 120

 Trp Ile Thr Tyr Ser Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg
                 125                 130                 135

 Arg Thr Trp Glu Glu Ser Leu Leu Ala Cys Thr Ser Lys Asn Ser
                 140                 145                 150

 Ser Leu Leu Ser Ile Asp Asn Glu Glu Glu Ile Lys Phe Leu Ala
                 155                 160                 165

 Ser Ile Leu Pro Ser Ser Trp Ile Gly Val Phe Arg Asn Ser Ser
                 170                 175                 180

 His His Pro Trp Val Thr Ile Asn Gly Leu Ala Phe Lys His Lys
                 185                 190                 195

 Ile Lys Asp Ser Asp Asn Ala Glu Leu Asn Cys Ala Val Leu Gln
                 200                 205                 210

 Val Asn Arg Leu Lys Ser Ala Gln Cys Gly Ser Ser Met Ile Tyr
                 215                 220                 225

 His Cys Lys His Lys Leu
                 230

<210> 5479
<211> 4360
<212> DNA
<213> Homo sapien

<400> 5479
 aaattctcca aatgtaccat attcttttct gactcagaaa gtatgctaaa 50

 atgttttcct cctttaaatc tttttcatct agttaactcc tatttatgct 100

 acagtactta gttttgagtc acttcctcaa aaaaaggttc ttgtaactgc 150

 ccctcatctt acactctgct acatgctgtt ttaacatact taattttttt 200

 gtacttatct aaatcatcac taaatatcgt taataaatta ttgaaaatta 250

 tataattgta attctatctc tagaatataa tctccatgag gaaaaagcat 300

 catgttcatg tctaattagt tcacattagt agcccctgaa gtgtggtgta 350

 tacagtagat tctgaatgtt aaaagaatac acagcaaata atttttgaat 400

 aattaaatag cattgaaaaa aatgtctagt ctccagtgtc attagtcatg 450

 ctttatgttt tctgtcagac tctgactgct gttcttgcca agaaaaatgg 500

 gttgggtacc ggtgcaactg ttacttcatt tccagtgaac agaaaacttg 550

 gaacgaaagt cggcatctct gtgcttctca gaaatccagc ctgcttcagc 600

 ttcaaaacac agatgaactg gcatgtgctg agtctgattt tctacatttt 650

 ctttgatcta gaaaaatata ctatctaaac aagttaaata ctttggttta 700

 agtcattaat cacatagtaa gtggatggtt atattggaat tgagttatct 750

 gttctgtgta ccttaaagta gtcattgtaa aatctttatt aaattcctta 800

 atgattatat catgggaata caaatcaaga taggtgccaa ataaagtgaa 850

 agaaactttt caggaagaat tcaaagaaga taataggtca ttatatttac 900

 ccattttatt tgaagaacca actaaatgac tgtgattctt aactctttta 950

 attgaattta taatatcttt tataatttta tagtttttgt catctttctg 1000

 ggatataagc tagtatggaa atatggtaag aaaacgtacc caattctttt 1050

 cttttctttt tttttttttt tttttgaaac agagttttac tctgttgccc 1100

 aggctggagt gcactggtgc aatttcagct cactgcagcc tccacctcct 1150

 gggttcaagt gattctcctg cctcagcctc ctgagtagct gggattacag 1200

 acacctgcca ccaggcctgg cactttttgt atttttagta gagacagggt 1250

 ttcaccgtat tggcgaggct ggtcttgaac tcctgacctc gggtgatcta 1300

 ccctccttgg cctcccaaag tgctaggatt acaggcatga gccaccgtgc 1350

 ctggccctaa ttacccaatt cttttttgtt tgtttgtttg tttgtttgtt 1400

 tgagatggag tctcgctctg tcgcccaggc tggagtgcag tggcgtgatc 1450

 ttggctcact gcaagctccg cctcccgggt tcacgccatt ctcctgcctc 1500

 agcctcccga gtagctggga ctacaggcgc ccacaaccac gcccagttaa 1550

 ttttgtgtat ttttagtaga gacgcggttt caccgtgtta gccaggatgg 1600

 tctcgatctt ctgacctcat gatctgccca cctctgcctc ccaaagtgct 1650

 gggattacag gcgtgagcca ccgtgcccgg cccctaatta cccagttctt 1700

 aagaaaaagt gcggccgggc gcagtggctg aaacctgtaa tcccagcact 1750

 ttgggaggcc gaggagggtg gatcacagtc aggagatcga gaccatcctg 1800

 gctaacacgg tgaaaccacg tctctactaa aaatacaaaa aattagccgg 1850

 gcgtggtggc gggcgcctgt agtcccagct actcgggagg cggaggcagg 1900

 agaatggcgt gaacctggga ggcagagctt gcagtgagct gagatcgtcc 1950

 cactgcactc cagcctgggc gacagagcaa gactccctct caacaaaaag 2000

 aaaaaagaaa aagcgaaaaa cttctcctgc tgcacgtggc acctttgcgg 2050

 attataggtt gagtagatta tacccatggg attcctcctt cacaatacca 2100

 tgattttgga atcaaattta atctttgatc ccccgtgaag aaagtgttcc 2150

 atgaaaactc tatctccttt tagaaggttt ttaattcttc aggaagtgag 2200

 attttgtggt attttttctc catatatgaa tgggcctgat aaatgagaac 2250

 tttcagtctt gtgattatac cttttaaata ggaagttaaa aataatttcc 2300

 gtttgtgtga tggacaggct gaatcttatt ctaaacactg actttccctc 2350

 aaaatatgtt attcccagaa tagattaaaa ttagattaat gtgattgtct 2400

 tttacttgaa gcaggatttt atgagctcca gtcaacaatt ttactggatt 2450

 ggactctctt acagtgagga gcacaccgcc tggttgtggg agaatggctc 2500

 tgcactctcc cagtatctgt aagtttctgg caatcatggc gttttttgct 2550

 ctttatgaat ttgtccttaa atgtgactag taaaggtaac atccaggagc 2600

 actgtggctg aaataacctt gtctagggca tgagaataca gtaaaaggaa 2650

 aaagtacaac aaaataacaa ttttagatct aggcagatct aaaccactct 2700

 aagtgttaaa atcaaaacag aagataatgc ctaatgaaag gaggtcgggg 2750

 tataggatag ttggtgcaaa aaaatactga taaccattac atgcttgcct 2800

 gtattatttt aaatttttta attaaaaata tattattttg tagtcacatg 2850

 gacaacaaaa ccaaaacatt acaaatctcc agaaagtgca atgcataagc 2900

 tctcttagtt caaattaaac atttgaaagg tattatattt catcctatat 2950

 cttttgtcag ttaactgaag tgcatttttc ctaaatcaat cttcatacaa 3000

 gaatgtgaag agggccaggg atggtggctt gagcatccaa gttaatgctc 3050

 aagtgacatg aaatttagtg tattcgtggc cataaaagaa cttttaacat 3100

 atgctttatt tttgccttag taccagcact tggaagtata tgtgcatgta 3150

 cagatactca tatacacaga ggcagtccaa aaaaatagta tatttttatt 3200

 ttatttattc tggtagaccc caatattctc agcatgctct tatgttttat 3250

 atactataga ctcattgtct gtatgtgtgt actttttgaa tctcattttc 3300

 atttataaac atgagatttg cagcatcaca cagggacaaa gtttatgctc 3350

 tggtttgttt tcctagacta gatcagataa tacatcttaa ataaaataga 3400

 agaaaagcat atcacatatt taaaccatta atgacaacag aaaaacagca 3450

 aggaaaaaat ccctggcctc agtgctattg attagtgaga aaataactgg 3500

 gtattttgta gcattacact agaaaatcat gaaaattgtg gtaactgaaa 3550

 aaaaaaggac tcaatatgtt agtatctcac tcaaatgctt ttaaaattat 3600

 atcatttaat tgaaaaatgc cctgaacatt cttacttcct ttttgtgtat 3650

 gtgaacattt tcttcttcat tacagatttc catcatttga aacttttaat 3700

 acaaagaact gcatagcgta taatccaaat ggaaatgctt tagatgaatc 3750

 ctgtgaagat aaaaatcgtt atatctgtaa gcaacagctc atttaaatgt 3800

 ttcttggggc agagaaggtg gagagtaaag acccaacatt actaacaatg 3850

 atacagttgc atgttatatt attactaatt gtctacttct ggagtctata 3900

 aaatgttttt aaacagtgtc atatacaatt gtcatgtatg tgaaacaatg 3950

 tgttttaaaa ttgatgaaat tcgttcacct acatttgaga attataaaat 4000

 taacataaag aattttgtat tttcatttaa tgtatataat gttaaattca 4050

 atgtagtttt attacacatt tatgtaattt tatttacatt cttgctaatt 4100

 ctcagcagaa atttaaataa gatttaattc acatcaaata aaatttagaa 4150

 aataaaattt aactcacact gcccaggctg gagcatagtg gcaagatcat 4200

 agctcattgc aagctcaagt gatcctcctg actcagcctc ccaagtagct 4250

 aggactgcag gcaccatgtc actatgcccg actaattttt aatttttaat 4300

 tttttgtcaa gacaaggtct tgctatgttg cccaggctgg tcttgaactc 4350

 ctggcctcaa 4360

<210> 5480
<211> 3242
<212> DNA
<213> Homo sapien

<400> 5480
 ggcacgaggc tcactcacag cctcccttcc ttctttctcc ctccgcctcc 50

 cgagcaccag cgcgctctga gctgccccca gggtccctcc cccgccgcca 100

 gcagcccatt tggagggagg aagtaaggga agaggagagg aaggggagcc 150

 ggaccgacta cccagacaga gccggtgaat gggtttgtgg tgacccccgc 200

 cccccacccc accctccctt cccacccgac ccccaacccc catccccagt 250

 tcgagccgcc gcccgaaagg ccgggccgtc gtcttaggag gagtcgccgc 300

 cgccgccacc tccgccatgg agctgatcac cattctcgag aagaccgtgt 350

 ctcccgatcg gctggagctg gaagcggcgc agaagttcct ggagcgtgcg 400

 gccgtggaga acctgcccac tttccttgtg gaactgtcca gagtgctggc 450

 aaatccagga aacagtcagg ttgccagagt tgcagctggt ctacaaatca 500

 agaactcttt gacatctaaa gatccagata tcaaggcaca atatcagcag 550

 aggtggcttg ctattgatgc taatgctcga cgagaagtca agaactatgt 600

 tttgcagaca ttgggtacag aaacttaccg gcctagttct gcctcacagt 650

 gtgtggctgg tattgcttgt gcagagatcc cagtaaacca gtggccagaa 700

 ctcattcctc agctggtggc caatgtcaca aaccccaaca gcacagagca 750

 catgaaggag tcgacattgg aagccatcgg ttatatttgc caagatatag 800

 acccagagca gctacaagat aaatccaatg agattctgac tgccataatc 850

 caggggatga ggaaagaaga gcctagtaat aatgtgaagc tagctgctac 900

 gaatgcactc ctgaactcat tggagttcac caaagcaaac tttgataaag 950

 agtctgaaag gcactttatt atgcaggtgg tctgtgaagc cacacagtgt 1000

 ccagatacga gggtacgagt ggctgcttta cagaatctgg tgaagataat 1050

 gtccttatat tatcagtaca tggagacata tatgggtcct gctctttttg 1100

 caatcacaat cgaagcaatg aaaagtgaca ttgatgaggt ggctttacaa 1150

 gggatagaat tctggtccaa tgtctgtgat gaggaaatgg atttggccat 1200

 tgaagcttca gaggcagcag aacaaggacg gccccctgag cacaccagca 1250

 agttttatgc gaagggagca ctacagtatc tggttccaat cctcacacag 1300

 acactaacta aacaggacga aaatgatgat gacgatgact ggaacccctg 1350

 caaagcagca ggggtgtgcc tcatgcttct ggccacctgc tgtgaagatg 1400

 acattgtccc acatgtcctc cccttcatta aagaacacat caagaaccca 1450

 gattggcggt accgggatgc agcagtgatg gcttttggtt gtatcttgga 1500

 aggaccagag cccagtcagc tcaaaccact agttatacag gctatgccca 1550

 ccctaataga attaatgaaa gaccccagtg tagttgttcg agatacagct 1600

 gcatggactg taggcagaat ttgtgagctg cttcctgaag ctgccatcaa 1650

 tgatgtctac ttggctcccc tgctacagtg tctgattgag ggtctcagtg 1700

 ctgaacccag agtggcttca aatgtgtgct gggctttctc cagtctggct 1750

 gaagctgctt atgaagctgc agacgttgct gatgatcagg aagaaccagc 1800

 tacttactgc ttatcttctt catttgaact catagttcag aagctcctag 1850

 agactacaga cagacctgat ggacaccaga acaacctgag gagttctgca 1900

 tatgaatctc tgatggaaat tgtgaaaaac agtgccaagg attgttatcc 1950

 tgctgtccag aaaacgactt tggtcatcat ggaacgactg caacaggttc 2000

 ttcagatgga gtcacatatc cagagcacat ccgatagaat ccagttcaat 2050

 gaccttcagt ctttactctg tgcaactctt cagaatgttc ttcggaaagt 2100

 gcaacatcaa gatgctttgc agatctctga tgtggttatg gcctccctgt 2150

 taaggatgtt ccaaagcaca gctgggtctg ggggagtaca agaggatgcc 2200

 ctgatggcag ttagcacact ggtggaagtg ttgggtggtg aattcctcaa 2250

 gtacatggag gcctttaaac ccttcctggg cattggatta aaaaattatg 2300

 ctgaatacca ggtttgtttg gcagctgtgg gcttagtggg agacttgtgc 2350

 cgtgccctgc aatccaacat catacctttc tgtgacgagg tgatgcagct 2400

 gcttctggaa aatttgggga atgagaacgt ccacaggtct gtgaagccgc 2450

 agattctgtc agtgtttggt gatattgccc ttgctattgg aggagagttt 2500

 aaaaaatact tagaggttgt attgaatact cttcagcagg cctcccaagc 2550

 ccaggtggac aagtcagact atgacatggt ggattatctg aatgagctaa 2600

 gggaaagctg cttggaagcc tatactggaa tcgtccaggg attaaagggg 2650

 gatcaggaga acgtacaccc ggatgtgatg ctggtacaac ccagagtaga 2700

 atttattctg tctttcattg accacattgc tggagatgag gatcacacag 2750

 atggagtagt agcttgtgct gctggactaa taggggactt atgtacagca 2800

 tttgggaagg atgtactgaa attagtagaa gctaggccaa tgatccatga 2850

 attgttaact gaagggcgga gatcgaagac taacaaagca aaaacccttg 2900

 ctacatgggc aacaaaagaa ctgaggaaac tgaagaacca agcttgatct 2950

 gttaccattg ggatgataac ctgaggaccc ccactggaaa tctcccatct 3000

 tttgaaaaac ctggaagtga ggagtgtgca cggatgctga atgtttggga 3050

 atgagaggat gagtgagtga ggcttgaaaa cacaccacat tgaaaatcct 3100

 gccacagcag cagccgcagc cgccaacagc agcgctgtta gtgagctaag 3150

 taagcactga cttcgtagaa aaccataaca tcggccatct tggaaaagag 3200

 aaaaacaatg gagttactta tttaaaaaaa aaaaaaaaaa aa 3242

<210> 5481
<211> 876
<212> PRT
<213> Homo sapien

<400> 5481
 Met Glu Leu Ile Thr Ile Leu Glu Lys Thr Val Ser Pro Asp Arg
   1               5                  10                  15

 Leu Glu Leu Glu Ala Ala Gln Lys Phe Leu Glu Arg Ala Ala Val
                  20                  25                  30

 Glu Asn Leu Pro Thr Phe Leu Val Glu Leu Ser Arg Val Leu Ala
                  35                  40                  45

 Asn Pro Gly Asn Ser Gln Val Ala Arg Val Ala Ala Gly Leu Gln
                  50                  55                  60

 Ile Lys Asn Ser Leu Thr Ser Lys Asp Pro Asp Ile Lys Ala Gln
                  65                  70                  75

 Tyr Gln Gln Arg Trp Leu Ala Ile Asp Ala Asn Ala Arg Arg Glu
                  80                  85                  90

 Val Lys Asn Tyr Val Leu Gln Thr Leu Gly Thr Glu Thr Tyr Arg
                  95                 100                 105

 Pro Ser Ser Ala Ser Gln Cys Val Ala Gly Ile Ala Cys Ala Glu
                 110                 115                 120

 Ile Pro Val Asn Gln Trp Pro Glu Leu Ile Pro Gln Leu Val Ala
                 125                 130                 135

 Asn Val Thr Asn Pro Asn Ser Thr Glu His Met Lys Glu Ser Thr
                 140                 145                 150

 Leu Glu Ala Ile Gly Tyr Ile Cys Gln Asp Ile Asp Pro Glu Gln
                 155                 160                 165

 Leu Gln Asp Lys Ser Asn Glu Ile Leu Thr Ala Ile Ile Gln Gly
                 170                 175                 180

 Met Arg Lys Glu Glu Pro Ser Asn Asn Val Lys Leu Ala Ala Thr
                 185                 190                 195

 Asn Ala Leu Leu Asn Ser Leu Glu Phe Thr Lys Ala Asn Phe Asp
                 200                 205                 210

 Lys Glu Ser Glu Arg His Phe Ile Met Gln Val Val Cys Glu Ala
                 215                 220                 225

 Thr Gln Cys Pro Asp Thr Arg Val Arg Val Ala Ala Leu Gln Asn
                 230                 235                 240

 Leu Val Lys Ile Met Ser Leu Tyr Tyr Gln Tyr Met Glu Thr Tyr
                 245                 250                 255

 Met Gly Pro Ala Leu Phe Ala Ile Thr Ile Glu Ala Met Lys Ser
                 260                 265                 270

 Asp Ile Asp Glu Val Ala Leu Gln Gly Ile Glu Phe Trp Ser Asn
                 275                 280                 285

 Val Cys Asp Glu Glu Met Asp Leu Ala Ile Glu Ala Ser Glu Ala
                 290                 295                 300

 Ala Glu Gln Gly Arg Pro Pro Glu His Thr Ser Lys Phe Tyr Ala
                 305                 310                 315

 Lys Gly Ala Leu Gln Tyr Leu Val Pro Ile Leu Thr Gln Thr Leu
                 320                 325                 330

 Thr Lys Gln Asp Glu Asn Asp Asp Asp Asp Asp Trp Asn Pro Cys
                 335                 340                 345

 Lys Ala Ala Gly Val Cys Leu Met Leu Leu Ala Thr Cys Cys Glu
                 350                 355                 360

 Asp Asp Ile Val Pro His Val Leu Pro Phe Ile Lys Glu His Ile
                 365                 370                 375

 Lys Asn Pro Asp Trp Arg Tyr Arg Asp Ala Ala Val Met Ala Phe
                 380                 385                 390

 Gly Cys Ile Leu Glu Gly Pro Glu Pro Ser Gln Leu Lys Pro Leu
                 395                 400                 405

 Val Ile Gln Ala Met Pro Thr Leu Ile Glu Leu Met Lys Asp Pro
                 410                 415                 420

 Ser Val Val Val Arg Asp Thr Ala Ala Trp Thr Val Gly Arg Ile
                 425                 430                 435

 Cys Glu Leu Leu Pro Glu Ala Ala Ile Asn Asp Val Tyr Leu Ala
                 440                 445                 450

 Pro Leu Leu Gln Cys Leu Ile Glu Gly Leu Ser Ala Glu Pro Arg
                 455                 460                 465

 Val Ala Ser Asn Val Cys Trp Ala Phe Ser Ser Leu Ala Glu Ala
                 470                 475                 480

 Ala Tyr Glu Ala Ala Asp Val Ala Asp Asp Gln Glu Glu Pro Ala
                 485                 490                 495

 Thr Tyr Cys Leu Ser Ser Ser Phe Glu Leu Ile Val Gln Lys Leu
                 500                 505                 510

 Leu Glu Thr Thr Asp Arg Pro Asp Gly His Gln Asn Asn Leu Arg
                 515                 520                 525

 Ser Ser Ala Tyr Glu Ser Leu Met Glu Ile Val Lys Asn Ser Ala
                 530                 535                 540

 Lys Asp Cys Tyr Pro Ala Val Gln Lys Thr Thr Leu Val Ile Met
                 545                 550                 555

 Glu Arg Leu Gln Gln Val Leu Gln Met Glu Ser His Ile Gln Ser
                 560                 565                 570

 Thr Ser Asp Arg Ile Gln Phe Asn Asp Leu Gln Ser Leu Leu Cys
                 575                 580                 585

 Ala Thr Leu Gln Asn Val Leu Arg Lys Val Gln His Gln Asp Ala
                 590                 595                 600

 Leu Gln Ile Ser Asp Val Val Met Ala Ser Leu Leu Arg Met Phe
                 605                 610                 615

 Gln Ser Thr Ala Gly Ser Gly Gly Val Gln Glu Asp Ala Leu Met
                 620                 625                 630

 Ala Val Ser Thr Leu Val Glu Val Leu Gly Gly Glu Phe Leu Lys
                 635                 640                 645

 Tyr Met Glu Ala Phe Lys Pro Phe Leu Gly Ile Gly Leu Lys Asn
                 650                 655                 660

 Tyr Ala Glu Tyr Gln Val Cys Leu Ala Ala Val Gly Leu Val Gly
                 665                 670                 675

 Asp Leu Cys Arg Ala Leu Gln Ser Asn Ile Ile Pro Phe Cys Asp
                 680                 685                 690

 Glu Val Met Gln Leu Leu Leu Glu Asn Leu Gly Asn Glu Asn Val
                 695                 700                 705

 His Arg Ser Val Lys Pro Gln Ile Leu Ser Val Phe Gly Asp Ile
                 710                 715                 720

 Ala Leu Ala Ile Gly Gly Glu Phe Lys Lys Tyr Leu Glu Val Val
                 725                 730                 735

 Leu Asn Thr Leu Gln Gln Ala Ser Gln Ala Gln Val Asp Lys Ser
                 740                 745                 750

 Asp Tyr Asp Met Val Asp Tyr Leu Asn Glu Leu Arg Glu Ser Cys
                 755                 760                 765

 Leu Glu Ala Tyr Thr Gly Ile Val Gln Gly Leu Lys Gly Asp Gln
                 770                 775                 780

 Glu Asn Val His Pro Asp Val Met Leu Val Gln Pro Arg Val Glu
                 785                 790                 795

 Phe Ile Leu Ser Phe Ile Asp His Ile Ala Gly Asp Glu Asp His
                 800                 805                 810

 Thr Asp Gly Val Val Ala Cys Ala Ala Gly Leu Ile Gly Asp Leu
                 815                 820                 825

 Cys Thr Ala Phe Gly Lys Asp Val Leu Lys Leu Val Glu Ala Arg
                 830                 835                 840

 Pro Met Ile His Glu Leu Leu Thr Glu Gly Arg Arg Ser Lys Thr
                 845                 850                 855

 Asn Lys Ala Lys Thr Leu Ala Thr Trp Ala Thr Lys Glu Leu Arg
                 860                 865                 870

 Lys Leu Lys Asn Gln Ala
                 875

<210> 5482
<211> 1991
<212> DNA
<213> Homo sapien

<400> 5482
 acaggggtga aggcccagag accagcagaa cggcatccca gccacgacgg 50

 ccactttgct ctgtctgctg tccgccacgg ccctgctctg ttccctggga 100

 cacccccgcc cccacctcct caggctgcct gatctgccca gctttccagc 150

 tttcctctgg attccggcct ctggtcatcc ctccccaccc tctctccaag 200

 gccctctcct ggtctccctt cttctagaac cccttcctcc acctccctct 250

 ctgcagaact tctcctttac cccccacccc ccaccactgc cccctttcct 300

 tttctgacct ccttttggag ggctcagcgc tgcccagacc ataggagaga 350

 tgtgggaggc tcagttcctg ggcttgctgt ttctgcagcc gctttgggtg 400

 gctccagtga agcctctcca gccaggggct gaggtcccgg tggtgtgggc 450

 ccaggagggg gctcctgccc agctcccctg cagccccaca atccccctcc 500

 aggatctcag ccttctgcga agagcagggg tcacttggca gcatcagcca 550

 gacagtggcc cgcccgctgc cgcccccggc catcccctgg cccccggccc 600

 tcacccggcg gcgccctcct cctgggggcc caggccccgc cgctacacgg 650

 tgctgagcgt gggtcccgga ggcctgcgca gcgggaggct gcccctgcag 700

 ccccgcgtcc agctggatga gcgcggccgg cagcgcgggg acttctcgct 750

 atggctgcgc ccagcccggc gcgcggacgc cggcgagtac cgcgccgcgg 800

 tgcacctcag ggaccgcgcc ctctcctgcc gcctccgtct gcgcctgggc 850

 caggcctcga tgactgccag ccccccagga tctctcagag cctccgactg 900

 ggtcattttg aactgctcct tcagccgccc tgaccgccca gcctctgtgc 950

 attggttccg gaaccggggc cagggccgag tccctgtccg ggagtccccc 1000

 catcaccact tagcggaaag cttcctcttc ctgccccaag tcagccccat 1050

 ggactctggg ccctggggct gcatcctcac ctacagagat ggcttcaacg 1100

 tctccatcat gtataacctc actgttctgg gtctggagcc cccaactccc 1150

 ttgacagtgt acgctggagc aggttccagg gtggggctgc cctgccgcct 1200

 gcctgctggt gtggggaccc ggtctttcct cactgccaag tggactcctc 1250

 ctgggggagg ccctgacctc ctggtgactg gagacaatgg cgactttacc 1300

 cttcgactag aggatgtgag ccaggcccag gctgggacct acacctgcca 1350

 tatccatctg caggaacagc agctcaatgc cactgtcaca ttggcaatca 1400

 tcacagtgac tcccaaatcc tttgggtcac ctggatccct ggggaagctg 1450

 ctttgtgagg tgactccagt atctggacaa gaacgctttg tgtggagctc 1500

 tctggacacc ccatcccaga ggagtttctc aggaccttgg ctggaggcac 1550

 aggaggccca gctcctttcc cagccttggc aatgccagct gtaccagggg 1600

 gagaggcttc ttggagcagc agtgtacttc acagagctgt ctagcccagg 1650

 tgcccaacgc tctgggagag ccccaggtgc cctcccagca ggccacctcc 1700

 tgctgtttct cacccttggt gtcctttctc tgctcctttt ggtgactgga 1750

 gcctttggct ttcacctttg gagaagacag tggcgaccaa gacgattttc 1800

 tgccttagag caagggattc accctccgca ggctcagagc aagatagagg 1850

 agctggagca agaaccggag ccggagccgg agccggaacc ggagcccgag 1900

 cccgagcccg agccggagca gctctgacct ggagctgagg cagccagcag 1950

 atctcagcag cccagtccaa ataaacgtcc tgtctagcag c 1991

<210> 5483
<211> 525
<212> PRT
<213> Homo sapien

<400> 5483
 Met Trp Glu Ala Gln Phe Leu Gly Leu Leu Phe Leu Gln Pro Leu
   1               5                  10                  15

 Trp Val Ala Pro Val Lys Pro Leu Gln Pro Gly Ala Glu Val Pro
                  20                  25                  30

 Val Val Trp Ala Gln Glu Gly Ala Pro Ala Gln Leu Pro Cys Ser
                  35                  40                  45

 Pro Thr Ile Pro Leu Gln Asp Leu Ser Leu Leu Arg Arg Ala Gly
                  50                  55                  60

 Val Thr Trp Gln His Gln Pro Asp Ser Gly Pro Pro Ala Ala Ala
                  65                  70                  75

 Pro Gly His Pro Leu Ala Pro Gly Pro His Pro Ala Ala Pro Ser
                  80                  85                  90

 Ser Trp Gly Pro Arg Pro Arg Arg Tyr Thr Val Leu Ser Val Gly
                  95                 100                 105

 Pro Gly Gly Leu Arg Ser Gly Arg Leu Pro Leu Gln Pro Arg Val
                 110                 115                 120

 Gln Leu Asp Glu Arg Gly Arg Gln Arg Gly Asp Phe Ser Leu Trp
                 125                 130                 135

 Leu Arg Pro Ala Arg Arg Ala Asp Ala Gly Glu Tyr Arg Ala Ala
                 140                 145                 150

 Val His Leu Arg Asp Arg Ala Leu Ser Cys Arg Leu Arg Leu Arg
                 155                 160                 165

 Leu Gly Gln Ala Ser Met Thr Ala Ser Pro Pro Gly Ser Leu Arg
                 170                 175                 180

 Ala Ser Asp Trp Val Ile Leu Asn Cys Ser Phe Ser Arg Pro Asp
                 185                 190                 195

 Arg Pro Ala Ser Val His Trp Phe Arg Asn Arg Gly Gln Gly Arg
                 200                 205                 210

 Val Pro Val Arg Glu Ser Pro His His His Leu Ala Glu Ser Phe
                 215                 220                 225

 Leu Phe Leu Pro Gln Val Ser Pro Met Asp Ser Gly Pro Trp Gly
                 230                 235                 240

 Cys Ile Leu Thr Tyr Arg Asp Gly Phe Asn Val Ser Ile Met Tyr
                 245                 250                 255

 Asn Leu Thr Val Leu Gly Leu Glu Pro Pro Thr Pro Leu Thr Val
                 260                 265                 270

 Tyr Ala Gly Ala Gly Ser Arg Val Gly Leu Pro Cys Arg Leu Pro
                 275                 280                 285

 Ala Gly Val Gly Thr Arg Ser Phe Leu Thr Ala Lys Trp Thr Pro
                 290                 295                 300

 Pro Gly Gly Gly Pro Asp Leu Leu Val Thr Gly Asp Asn Gly Asp
                 305                 310                 315

 Phe Thr Leu Arg Leu Glu Asp Val Ser Gln Ala Gln Ala Gly Thr
                 320                 325                 330

 Tyr Thr Cys His Ile His Leu Gln Glu Gln Gln Leu Asn Ala Thr
                 335                 340                 345

 Val Thr Leu Ala Ile Ile Thr Val Thr Pro Lys Ser Phe Gly Ser
                 350                 355                 360

 Pro Gly Ser Leu Gly Lys Leu Leu Cys Glu Val Thr Pro Val Ser
                 365                 370                 375

 Gly Gln Glu Arg Phe Val Trp Ser Ser Leu Asp Thr Pro Ser Gln
                 380                 385                 390

 Arg Ser Phe Ser Gly Pro Trp Leu Glu Ala Gln Glu Ala Gln Leu
                 395                 400                 405

 Leu Ser Gln Pro Trp Gln Cys Gln Leu Tyr Gln Gly Glu Arg Leu
                 410                 415                 420

 Leu Gly Ala Ala Val Tyr Phe Thr Glu Leu Ser Ser Pro Gly Ala
                 425                 430                 435

 Gln Arg Ser Gly Arg Ala Pro Gly Ala Leu Pro Ala Gly His Leu
                 440                 445                 450

 Leu Leu Phe Leu Thr Leu Gly Val Leu Ser Leu Leu Leu Leu Val
                 455                 460                 465

 Thr Gly Ala Phe Gly Phe His Leu Trp Arg Arg Gln Trp Arg Pro
                 470                 475                 480

 Arg Arg Phe Ser Ala Leu Glu Gln Gly Ile His Pro Pro Gln Ala
                 485                 490                 495

 Gln Ser Lys Ile Glu Glu Leu Glu Gln Glu Pro Glu Pro Glu Pro
                 500                 505                 510

 Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Pro Glu Gln Leu
                 515                 520                 525

<210> 5484
<211> 3868
<212> DNA
<213> Homo sapien

<400> 5484
 atgaacctct gaaaactgcc ggcatctgag gtttcctcca aggccctctg 50

 aagtgcagcc cataatgaag gtcttggcgg caggagttgt gcccctgctg 100

 ttggttctgc actggaaaca tggggcgggg agccccctcc ccatcacccc 150

 tgtcaacgcc acctgtgcca tacgccaccc atgtcacaac aacctcatga 200

 accagatcag gagccaactg gcacagctca atggcagtgc caatgccctc 250

 tttattctct attacacagc ccagggggag ccgttcccca acaacctgga 300

 caagctatgt ggccccaacg tgacggactt cccgcccttc cacgccaacg 350

 gcacggagaa ggccaagctg gtggagctgt accgcatagt cgtgtacctt 400

 ggcacctccc tgggcaacat cacccgggac cagaagatcc tcaaccccag 450

 tgccctcagc ctccacagca agctcaacgc caccgccgac atcctgcgag 500

 gcctccttag caacgtgctg tgccgcctgt gcagcaagta ccacgtgggc 550

 catgtggacg tgacctacgg ccctgacacc tcgggtaagg atgtcttcca 600

 gaagaagaag ctgggctgtc aactcctggg gaagtataag cagatcatcg 650

 ccgtgttggc ccaggccttc tagcaggagg tcttgaagtg tgctgtgaac 700

 cgagggatct caggagttgg gtccagatgt gggggcctgt ccaagggtgg 750

 ctggggccca gggcatcgct aaacccaaat gggggctgct ggcagacccc 800

 gagggtgcct ggccagtcca ctccactctg ggctgggctg tgatgaagct 850

 gagcagagtg gaaacttcca tagggaggga gctagaagaa ggtgcccctt 900

 cctctgggag attgtggact ggggagcgtg ggctggactt ctgcctctac 950

 ttgtcccttt ggccccttgc tcactttgtg cagtgaacaa actacacaag 1000

 tcatctacaa gagccctgac cacagggtga gacagcaggg cccaggggag 1050

 tggaccagcc cccagcaaat tatcaccatc tgtgcctttg ctgcccctta 1100

 ggttgggact taggtgggcc agaggggcta ggatcccaaa ggactccttg 1150

 tcccctagaa gtttgatgag tggaagatag agaggggcct ctgggatgga 1200

 aggctgtctt cttttgagga tgatcagaga acttgggcat aggaacaatc 1250

 tggcagaagt ttccagaagg aggtcacttg gcattcaggc tcttggggag 1300

 gcagagaagc caccttcagg cctgggaagg aagacactgg gaggaggaga 1350

 ggcctggaaa gctttggtag gttcttcgtt ctcttccccg tgatcttccc 1400

 tgcagcctgg gatggccagg gtctgatggc tggacctgca gcaggggttt 1450

 gtggaggtgg gtagggcagg ggcaggttgc taagtcaggt gcagaggttc 1500

 tgagggaccc aggctcttcc tctgggtaaa ggtctgtaag aaggggctgg 1550

 ggtagctcag agtagcagct cacatctgag gccctgggag gtcttgtgag 1600

 gtcacacaga ggtacttgag ggggactgga ggccgtctct ggtccccagg 1650

 gcaagggaac agcagaactt agggtcaggg tctcagggaa ccctgagctc 1700

 caagcgtgct gtgcgtctga cctggcatga tttctattta ttatgatatc 1750

 ctatttatat taacttattg gtgctttcag tggccaagtt aattcccctt 1800

 tccctggtcc ctactcaaca aaatatgatg atggctcccg acacaagcgc 1850

 cagggccagg gcttagcagg gcctggtctg gaagtcgaca atgttacaag 1900

 tggaataagc ttacgggtga agctcagaga agggtcggat ctgagagaat 1950

 ggggaggcct gagtgggagt ggggggcctt gctccacccc catcccctac 2000

 tgtgacttgc tttagcgtgt cagggtccag gctgcagggg ctgggccaat 2050

 ttgtggagag gccgggtgcc tttctgtctt gcttccaggg ggctggttca 2100

 cactgttctt gggcgcccca gcattgtgtt gtgaggcgca ctgttcctgg 2150

 cagatattgt gccccctgga gcagtgggca agacagtcct tgtggcccac 2200

 cctgtccttg tttctgtgtc cccatgctgc ctctgaaata gcgccctgga 2250

 acaaccctgc ccctgcaccc agcatgctcc gacacagcag ggaagctcct 2300

 cctgtggccc ggacacccat agacggtgcg gggggcctgg ctgggccaga 2350

 ccccaggaag gtggggtaga ctggggggat cagctgccca ttgctcccaa 2400

 gaggaggaga gggaggctgc agacgcctgg gactcagacc aggaagctgt 2450

 gggccctcct gctccacccc catcccactc ccacccatgt ctgggctccc 2500

 aggcagggaa cccgatctct tcctttgtgc tggggccagg cgagtggaga 2550

 aacgccctcc agtctgagag caggggaggg aaggaggcag cagagttggg 2600

 gcagctgctc agagcagtgt tctggcttct tctcaaaccc tgagcgggct 2650

 gccggcctcc aagttcctcc gacaagatga tggtactaat tatggtactt 2700

 ttcactcact ttgcaccttt ccctgtcgct ctctaagcac tttacctgga 2750

 tggcgcgtgg gcagtgtgca ggcaggtcct gaggcctggg gttggggtgg 2800

 agggtgcggc ccggagttgt ccatctgtcc atcccaacag caagacgagg 2850

 atgtggctgt tgagatgtgg gccacactca cccttgtcca ggatgcaggg 2900

 actgccttct ccttcctgct tcatccggct tagcttgggg ctggctgcat 2950

 tcccccagga tgggcttcga gaaagacaaa cttgtctgga aaccagagtt 3000

 gctgattcca cccggggggc ccggctgact cgcccatcac ctcatctccc 3050

 tgtggacttg ggagctctgt gccaggccca ccttgcggcc ctggctctga 3100

 gtcgctctcc cacccagcct ggacttggcc ccatgggacc catcctcagt 3150

 gctccctcca gatcccgtcc ggcagcttgg cgtccaccct gcacagcatc 3200

 actgaatcac agagcctttg cgtgaaacag ctctgccagg ccgggagctg 3250

 ggtttctctt ccctttttat ctgctggtgt ggaccacacc tgggcctggc 3300

 cggaggaaga gagagtttac caagagagat gtctccgggc ccttatttat 3350

 tatttaaaca tttttttaaa aagcactgct agtttacttg tctctcctcc 3400

 ccatcgtccc catcgtcctc cttgtccctg acttggggca cttccaccct 3450

 gacccagcca gtccagctct gccttgccgg ctctccagag tagacatagt 3500

 gtgtggggtt ggagctctgg cacccgggga ggtagcattt ccctgcagat 3550

 ggtacagatg ttcctgcctt agagtcatct ctagttcccc acctcaatcc 3600

 cggcatccag ccttcagtcc cgcccacgtg ctagctccgt gggcccaccg 3650

 tgcggcctta gaggtttccc tccttccttt ccactgaaaa gcacatggcc 3700

 ttgggtgaca aattcctctt tgatgaatgt accctgtggg gatgtttcat 3750

 actgacagat tatttttatt tattcaatgt catatttaaa atatttattt 3800

 tttataccaa atgaatcact ttttttttta agaaaaaaaa gagaaatgaa 3850

 taaagaatct actcttcg 3868

<210> 5485
<211> 202
<212> PRT
<213> Homo sapien

<400> 5485
 Met Lys Val Leu Ala Ala Gly Val Val Pro Leu Leu Leu Val Leu
   1               5                  10                  15

 His Trp Lys His Gly Ala Gly Ser Pro Leu Pro Ile Thr Pro Val
                  20                  25                  30

 Asn Ala Thr Cys Ala Ile Arg His Pro Cys His Asn Asn Leu Met
                  35                  40                  45

 Asn Gln Ile Arg Ser Gln Leu Ala Gln Leu Asn Gly Ser Ala Asn
                  50                  55                  60

 Ala Leu Phe Ile Leu Tyr Tyr Thr Ala Gln Gly Glu Pro Phe Pro
                  65                  70                  75

 Asn Asn Leu Asp Lys Leu Cys Gly Pro Asn Val Thr Asp Phe Pro
                  80                  85                  90

 Pro Phe His Ala Asn Gly Thr Glu Lys Ala Lys Leu Val Glu Leu
                  95                 100                 105

 Tyr Arg Ile Val Val Tyr Leu Gly Thr Ser Leu Gly Asn Ile Thr
                 110                 115                 120

 Arg Asp Gln Lys Ile Leu Asn Pro Ser Ala Leu Ser Leu His Ser
                 125                 130                 135

 Lys Leu Asn Ala Thr Ala Asp Ile Leu Arg Gly Leu Leu Ser Asn
                 140                 145                 150

 Val Leu Cys Arg Leu Cys Ser Lys Tyr His Val Gly His Val Asp
                 155                 160                 165

 Val Thr Tyr Gly Pro Asp Thr Ser Gly Lys Asp Val Phe Gln Lys
                 170                 175                 180

 Lys Lys Leu Gly Cys Gln Leu Leu Gly Lys Tyr Lys Gln Ile Ile
                 185                 190                 195

 Ala Val Leu Ala Gln Ala Phe
                 200

<210> 5486
<211> 848
<212> DNA
<213> Homo sapien

<400> 5486
 cagtctcaat gggggcactg gggctggagg gcaggggtgg gaggctccag 50

 gggaggggtt ccctcctgct agctgtggca ggagccactt ctctggtgac 100

 cttgttgctg gcggtgccta tcactgtcct ggctgtgctg gccttagtgc 150

 cccaggatca gggaggactg ggtttcagaa gctgccagag gaggagccag 200

 aaacagatct cagccccggg ctcccagctg cccacctcat aggcgctccg 250

 ctgaaggggc aggggctagg ctgggagacg acgaaggaac aggcgtttct 300

 gacgagcggg acgcagttct cggacgccga ggggctggcg ctcccgcagg 350

 acggcctcta ttacctctac tgtctcgtcg gctaccgggg ccgggcgccc 400

 cctggcggcg gggaccccca gggccgctcg gtcacgctgc gcagctctct 450

 gtaccgggcg gggggcgcct acgggccggg cactcccgag ctgctgctcg 500

 agggcgccga gacggtgact ccagtgctgg acccggccag gagacaaggg 550

 tacgggcctc tctggtacac gagcgtgggg ttcggcggcc tggtgcagct 600

 ccggaggggc gagagggtgt acgtcaacat cagtcacccc gatatggtgg 650

 acttcgcgag agggaagacc ttctttgggg ccgtgatggt ggggtgaggg 700

 aatatgagtg cgtggtgcga gtgcgtgaat attgggggcc cggacgccca 750

 ggaccccatg gcagtgggaa aaatgtagga gactgtttgg aaattgattt 800

 tgaacctgat gaaaataaag aatggaaagc ttcagtgctg ccgataaa 848

<210> 5487
<211> 77
<212> PRT
<213> Homo sapien

<400> 5487
 Met Gly Ala Leu Gly Leu Glu Gly Arg Gly Gly Arg Leu Gln Gly
   1               5                  10                  15

 Arg Gly Ser Leu Leu Leu Ala Val Ala Gly Ala Thr Ser Leu Val
                  20                  25                  30

 Thr Leu Leu Leu Ala Val Pro Ile Thr Val Leu Ala Val Leu Ala
                  35                  40                  45

 Leu Val Pro Gln Asp Gln Gly Gly Leu Gly Phe Arg Ser Cys Gln
                  50                  55                  60

 Arg Arg Ser Gln Lys Gln Ile Ser Ala Pro Gly Ser Gln Leu Pro
                  65                  70                  75

 Thr Ser


<210> 5488
<211> 6928
<212> DNA
<213> Homo sapien

<400> 5488
 ggcgggagcg cgtgcgcccg aggacccggc cggaaggctt gcgccagctc 50

 aggatgagga caggctgggc gacccctcgc cgcccggcgg ggctcctcat 100

 gctgctcttc tggttcttcg atctcgcgga gccctctggc cgcgcagcta 150

 atgacccctt caccatcgtc catggaaata cgggcaagtg catcaagcca 200

 gtgtatggct ggatagtagc agacgactgt gatgaaactg aggacaagtt 250

 atggaagtgg gtgtcccagc atcggctctt tcatttgcac tcccaaaagt 300

 gccttggcct cgatattacc aaatcggtaa atgagctgag aatgttcagc 350

 tgtgactcca gtgccatgct gtggtggaaa tgtgagcacc actctctgta 400

 cggagctgcc cggtaccggc tggctctgaa ggatggacat ggcacagcaa 450

 tctcaaatgc atctgatgtc tggaagaaag gaggctcaga ggaaagcctt 500

 tgtgaccagc cttatcatga gatctatacc agagatggga actcttatgg 550

 gagaccttgt gaatttccat tcttaattga tgggacctgg catcatgatt 600

 gcattcttga tgaagatcat agtgggccat ggtgtgccac caccttaaat 650

 tatgaatatg accgaaagtg gggcatctgc ttaaagcctg aaaacggttg 700

 tgaagataat tgggaaaaga acgagcagtt tggaagttgc taccaattta 750

 atactcagac ggctctttct tggaaagaag cttatgtttc atgtcagaat 800

 caaggagctg atttactgag catcaacagt gctgctgaat taacttacct 850

 taaagaaaaa gaaggcattg ctaagatttt ctggattggt ttaaatcagc 900

 tatactctgc tagaggctgg gaatggtcag accacaaacc attaaacttt 950

 ctcaactggg atccagacag gcccagtgca cctactatag gtggctccag 1000

 ctgtgcaaga atggatgctg agtctggtct gtggcagagc ttttcctgtg 1050

 aagctcaact gccctatgtc tgcaggaaac cattaaataa tacagtggag 1100

 ttaacagatg tctggacata ctcagatacc cgctgtgatg caggctggct 1150

 gccaaataat ggattttgct atctgctggt aaatgaaagt aattcctggg 1200

 ataaggcaca tgcgaaatgc aaagccttca gtagtgacct aatcagcatt 1250

 cattctctag cagatgtgga ggtggttgtc acaaaactcc ataatgagga 1300

 tatcaaagaa gaagtgtgga taggccttaa gaacataaac ataccaactt 1350

 tatttcagtg gtcagatggt actgaagtta ctctaacata ttgggatgag 1400

 aatgagccaa atgttcccta caataagacg cccaactgtg tttcctactt 1450

 aggagagcta ggtcagtgga aagtccaatc atgtgaggag aaactaaaat 1500

 atgtatgcaa gagaaaggga gaaaaactga atgacgcaag ttctgataag 1550

 atgtgtcctc cagatgaggg ctggaagaga catggagaaa cctgttacaa 1600

 gatttatgag gatgaggtcc cttttggaac aaactgcaat ctgactatca 1650

 ctagcagatt tgagcaagaa tacctaaatg atttgatgaa aaagtatgat 1700

 aaatctctaa gaaaatactt ctggactggc ctgagagatg tagattcttg 1750

 tggagagtat aactgggcaa ctgttggtgg aagaaggcgg gctgtaacct 1800

 tttccaactg gaattttctt gagccagctt ccccgggcgg ctgcgtggct 1850

 atgtctactg gaaagtctgt tggaaagtgg gaggtgaagg actgcagaag 1900

 cttcaaagca ctttcaattt gcaagaaaat gagtggaccc cttgggcctg 1950

 aagaagcatc ccctaagcct gatgacccct gtcctgaagg ctggcagagt 2000

 ttccccgcaa gtctttcttg ttataaggta ttccatgcag aaagaattgt 2050

 aagaaagagg aactgggaag aagctgaacg attctgccaa gcccttggag 2100

 cacacctttc tagcttcagc catgtggatg aaataaagga atttcttcac 2150

 tttttaacgg accagttcag tggccagcat tggctgtgga ttggtttgaa 2200

 taaaaggagc ccagatttac aaggatcctg gcaatggagt gatcgtacac 2250

 cagtgtctac tattatcatg ccaaatgagt ttcagcagga ttatgacatc 2300

 agagactgtg ctgctgtcaa ggtatttcat aggccatggc gaagaggctg 2350

 gcatttctat gatgatagag aatttattta tttgaggcct tttgcttgtg 2400

 atacaaaact tgaatgggtg tgccaaattc caaaaggccg tactccaaaa 2450

 acaccagact ggtacaatcc agaccgtgct ggaattcatg gacctccact 2500

 tataattgaa ggaagtgaat attggtttgt tgctgatctt cacctaaact 2550

 atgaagaagc cgtcctgtac tgtgccagca atcacagctt tcttgcgact 2600

 ataacatctt ttgtgggact aaaagccatc aaaaacaaaa tagcaaatat 2650

 atctggtgat ggacagaagt ggtggataag aattagcgag tggccaatag 2700

 atgatcattt tacatactca cgatatccat ggcaccgctt tcctgtgaca 2750

 tttggagagg aatgcttgta catgtctgcc aagacttggc ttatcgactt 2800

 aggtaaacca acagactgta gtaccaagtt gcccttcatc tgtgaaaaat 2850

 ataatgtttc ttcgttagag aaatacagcc cagattctgc agctaaagtg 2900

 caatgttctg agcaatggat tccttttcag aataagtgtt ttctaaagat 2950

 caaacccgtg tctctcacat tttctcaagc aagcgatacc tgtcactcct 3000

 atggtggcac ccttccttca gtgttgagcc agattgaaca agactttatt 3050

 acatccttgc ttccggatat ggaagctact ttatggattg gtttgcgctg 3100

 gactgcctat gaaaagataa acaaatggac agataacaga gagctgacgt 3150

 acagtaactt tcacccatta ttggttagtg ggaggctgag aataccagaa 3200

 aatttttttg aggaagagtc tcgctaccac tgtgccctaa tactcaacct 3250

 ccaaaaatca ccgtttactg ggacgtggaa ttttacatcc tgcagtgaac 3300

 gccactttgt gtctctctgt cagaaatatt cagaagttaa aagcagacag 3350

 acgttgcaga atgcttcaga aactgtaaag tatctaaata atctgtacaa 3400

 aataatccca aagactctga cttggcacag tgctaaaagg gagtgtctga 3450

 aaagtaacat gcagctggtg agcatcacgg acccttacca gcaggcattc 3500

 ctcagtgtgc aggcgctcct tcacaactct tccttatgga tcggactctt 3550

 cagtcaagat gatgaactca actttggttg gtcagatggg aaacgtcttc 3600

 attttagtcg ctgggctgaa actaatgggc aactcgaaga ctgtgtagta 3650

 ttagacactg atggattctg gaaaacagtt gattgcaatg acaatcaacc 3700

 aggtgctatt tgctactatt caggaaatga gactgaaaaa gaggtcaaac 3750

 cagttgacag tgttaaatgt ccatctcctg ttctaaatac tccgtggata 3800

 ccatttcaga actgttgcta caatttcata ataacaaaga ataggcatat 3850

 ggcaacaaca caggatgaag ttcatactaa atgccagaaa ctgaatccaa 3900

 aatcacatat tctgagtatt cgagatgaaa aggagaataa ctttgttctt 3950

 gagcaactgc tgtacttcaa ttatatggct tcatgggtca tgttaggaat 4000

 aacttataga aataattctc ttatgtggtt tgataagacc ccactgtcat 4050

 atacacattg gagagcagga agaccaacta taaaaaatga gaagtttttg 4100

 gctggtttaa gtactgacgg cttctgggat attcaaacct ttaaagttat 4150

 tgaagaagca gtttattttc accagcacag cattcttgct tgtaaaattg 4200

 aaatggttga ctacaaagaa gaacataata ctacactgcc acagtttatg 4250

 ccatatgaag atggtattta cagtgttatt caaaaaaagg taacatggta 4300

 tgaagcatta aacatgtgtt ctcaaagtgg aggtcacttg gcaagcgttc 4350

 acaaccaaaa tggccagctc tttctggaag atattgtaaa acgtgatgga 4400

 tttccactat gggttgggct ctcaagtcat gatggaagtg aatcaagttt 4450

 tgaatggtct gatggtagta catttgacta tatcccatgg aaaggccaaa 4500

 catctcctgg aaattgtgtt ctcttggatc caaaaggaac ttggaaacat 4550

 gaaaaatgca actctgttaa ggatggtgct atttgttata aacctacaaa 4600

 atctaaaaag ctgtcccgtc ttacatattc atcaagatgt ccagcagcaa 4650

 aagagaatgg gtcacggtgg atccagtaca agggtcactg ttacaagtct 4700

 gatcaggcat tgcacagttt ttcagaggcc aaaaaattgt gttcaaaaca 4750

 tgatcactct gcaactatcg tttccataaa agatgaagat gagaataaat 4800

 ttgtgagcag actgatgagg gaaaataata acattaccat gagagtttgg 4850

 cttggattat ctcaacattc tgttgaccag tcttggagtt ggttagatgg 4900

 atcagaagtg acatttgtca aatgggaaaa taaaagtaag agtggtgttg 4950

 gaagatgtag catgttgata gcttcaaatg aaacttggaa aaaagttgaa 5000

 tgtgaacatg gttttggaag agttgtctgc aaagtgcctc tgggccctga 5050

 ttacacagca atagctatca tagttgccac actaagtatc ttagttctca 5100

 tgggcggact gatttggttc ctcttccaaa ggcaccgttt gcacctggcg 5150

 ggtttctcat cagttcgata tgcacaagga gtgaatgaag atgagattat 5200

 gcttccttct ttccatgact aaattcttct aaaagttttc taatttgcac 5250

 taatgtggtt atggagaaat tagtcactta aaatgtccca gtgtcagtat 5300

 ttactctgct ccaaagtaga actcttaaat actttttcag ttgtttagat 5350

 cttaggcatg tgctggtatc cacagttaat tccctgctaa atgccatgtt 5400

 tatcacccta attaatagaa tggaggggac tccaaagctg gaactgaagt 5450

 ccaaattgtt tgtacagtaa tatgtttaat gttcattttc tctgtatgaa 5500

 tgtgattggt aactaggata tgtatatttt aatagaattt ttaacaaaac 5550

 ttcttagaaa attaaaatag gcatattact aggtgacatg tctacttttt 5600

 aatttttaag agcatccggc caaatgcaaa attagtacct caaagtaaaa 5650

 attgaactgt aaactctatc agcattgttt caaaatagtc atttttagca 5700

 ctggggaaaa ataaacaata agacatgctt actttttaat ttttattttt 5750

 ttgagactga gtctctctct gttgcccagg ctggagtaca atggcgtgat 5800

 ctcggctcac tgcaaatctc cgcctcccag gttcaagcga ttctcctgcc 5850

 tcagcctcct gagtagctgg gattacaggc aactgccacc atgcccggct 5900

 aatttttgta tttttagtag agatggggtt tcaccatgtt ggccaggctg 5950

 gtctcgaact cgtgaccgca gtgatcctcc cgcctcggcc tcccaaagtg 6000

 ctgggattac aggcatgagc caccgcgcct ggcctctgct tactttttat 6050

 atagcaaaat gattcccctt ggcaagatgt ttcttatatt attccaaagt 6100

 tatttcatac cattattatg taaatatgaa gagttttttt ctgtttataa 6150

 ttgtttataa aacaatgact tttaaagatt tagtgcttaa cattttccca 6200

 agtgtgggaa cattattttt agattgagta ggtaccttgt agcagtgtgc 6250

 tttgcatttt ctgatgtatt acatgactgt ttcttttgta aagagaatca 6300

 actaggtatt taagactgat aattttacaa tttatatgct tcacatagca 6350

 tgtcaacttt tgactaagaa ttttgtttta cttttttaac atgtgttaaa 6400

 cagagaaagg gtccatgaag gaaagtgtat gagttgcatt tgtaaaaatg 6450

 agactttttc agtggaactc taaaccttgt gatgactact aacaaatgta 6500

 aaattatgag tgattaagaa aacattgctt tgtggttatc actttaagtt 6550

 ttgacaccta gattatagtc ttagtaatag catccactgg aaaaggtgaa 6600

 aatgttttat tcagcattta acttacattt gtactttaga gtatttttgt 6650

 ataaaatcca tagatttatt ttacatttag agtatttaca ctatgataaa 6700

 gttgtaaata attttctaag acagttttta tatagtctac agttgtcctg 6750

 atttcttatt gaatttgtta gactagttct cttgtcttgt gatctgtgta 6800

 caattttagt cactaagact ttcctccaag aactaagcca acttgatgtg 6850

 aaaagcacgg ctgtatataa tggtgatgtc ataataaagt tgttttatct 6900

 tttaagtaaa aaaaaaaaaa aaaaaaaa 6928

<210> 5489
<211> 1722
<212> PRT
<213> Homo sapien

<400> 5489
 Met Arg Thr Gly Trp Ala Thr Pro Arg Arg Pro Ala Gly Leu Leu
   1               5                  10                  15

 Met Leu Leu Phe Trp Phe Phe Asp Leu Ala Glu Pro Ser Gly Arg
                  20                  25                  30

 Ala Ala Asn Asp Pro Phe Thr Ile Val His Gly Asn Thr Gly Lys
                  35                  40                  45

 Cys Ile Lys Pro Val Tyr Gly Trp Ile Val Ala Asp Asp Cys Asp
                  50                  55                  60

 Glu Thr Glu Asp Lys Leu Trp Lys Trp Val Ser Gln His Arg Leu
                  65                  70                  75

 Phe His Leu His Ser Gln Lys Cys Leu Gly Leu Asp Ile Thr Lys
                  80                  85                  90

 Ser Val Asn Glu Leu Arg Met Phe Ser Cys Asp Ser Ser Ala Met
                  95                 100                 105

 Leu Trp Trp Lys Cys Glu His His Ser Leu Tyr Gly Ala Ala Arg
                 110                 115                 120

 Tyr Arg Leu Ala Leu Lys Asp Gly His Gly Thr Ala Ile Ser Asn
                 125                 130                 135

 Ala Ser Asp Val Trp Lys Lys Gly Gly Ser Glu Glu Ser Leu Cys
                 140                 145                 150

 Asp Gln Pro Tyr His Glu Ile Tyr Thr Arg Asp Gly Asn Ser Tyr
                 155                 160                 165

 Gly Arg Pro Cys Glu Phe Pro Phe Leu Ile Asp Gly Thr Trp His
                 170                 175                 180

 His Asp Cys Ile Leu Asp Glu Asp His Ser Gly Pro Trp Cys Ala
                 185                 190                 195

 Thr Thr Leu Asn Tyr Glu Tyr Asp Arg Lys Trp Gly Ile Cys Leu
                 200                 205                 210

 Lys Pro Glu Asn Gly Cys Glu Asp Asn Trp Glu Lys Asn Glu Gln
                 215                 220                 225

 Phe Gly Ser Cys Tyr Gln Phe Asn Thr Gln Thr Ala Leu Ser Trp
                 230                 235                 240

 Lys Glu Ala Tyr Val Ser Cys Gln Asn Gln Gly Ala Asp Leu Leu
                 245                 250                 255

 Ser Ile Asn Ser Ala Ala Glu Leu Thr Tyr Leu Lys Glu Lys Glu
                 260                 265                 270

 Gly Ile Ala Lys Ile Phe Trp Ile Gly Leu Asn Gln Leu Tyr Ser
                 275                 280                 285

 Ala Arg Gly Trp Glu Trp Ser Asp His Lys Pro Leu Asn Phe Leu
                 290                 295                 300

 Asn Trp Asp Pro Asp Arg Pro Ser Ala Pro Thr Ile Gly Gly Ser
                 305                 310                 315

 Ser Cys Ala Arg Met Asp Ala Glu Ser Gly Leu Trp Gln Ser Phe
                 320                 325                 330

 Ser Cys Glu Ala Gln Leu Pro Tyr Val Cys Arg Lys Pro Leu Asn
                 335                 340                 345

 Asn Thr Val Glu Leu Thr Asp Val Trp Thr Tyr Ser Asp Thr Arg
                 350                 355                 360

 Cys Asp Ala Gly Trp Leu Pro Asn Asn Gly Phe Cys Tyr Leu Leu
                 365                 370                 375

 Val Asn Glu Ser Asn Ser Trp Asp Lys Ala His Ala Lys Cys Lys
                 380                 385                 390

 Ala Phe Ser Ser Asp Leu Ile Ser Ile His Ser Leu Ala Asp Val
                 395                 400                 405

 Glu Val Val Val Thr Lys Leu His Asn Glu Asp Ile Lys Glu Glu
                 410                 415                 420

 Val Trp Ile Gly Leu Lys Asn Ile Asn Ile Pro Thr Leu Phe Gln
                 425                 430                 435

 Trp Ser Asp Gly Thr Glu Val Thr Leu Thr Tyr Trp Asp Glu Asn
                 440                 445                 450

 Glu Pro Asn Val Pro Tyr Asn Lys Thr Pro Asn Cys Val Ser Tyr
                 455                 460                 465

 Leu Gly Glu Leu Gly Gln Trp Lys Val Gln Ser Cys Glu Glu Lys
                 470                 475                 480

 Leu Lys Tyr Val Cys Lys Arg Lys Gly Glu Lys Leu Asn Asp Ala
                 485                 490                 495

 Ser Ser Asp Lys Met Cys Pro Pro Asp Glu Gly Trp Lys Arg His
                 500                 505                 510

 Gly Glu Thr Cys Tyr Lys Ile Tyr Glu Asp Glu Val Pro Phe Gly
                 515                 520                 525

 Thr Asn Cys Asn Leu Thr Ile Thr Ser Arg Phe Glu Gln Glu Tyr
                 530                 535                 540

 Leu Asn Asp Leu Met Lys Lys Tyr Asp Lys Ser Leu Arg Lys Tyr
                 545                 550                 555

 Phe Trp Thr Gly Leu Arg Asp Val Asp Ser Cys Gly Glu Tyr Asn
                 560                 565                 570

 Trp Ala Thr Val Gly Gly Arg Arg Arg Ala Val Thr Phe Ser Asn
                 575                 580                 585

 Trp Asn Phe Leu Glu Pro Ala Ser Pro Gly Gly Cys Val Ala Met
                 590                 595                 600

 Ser Thr Gly Lys Ser Val Gly Lys Trp Glu Val Lys Asp Cys Arg
                 605                 610                 615

 Ser Phe Lys Ala Leu Ser Ile Cys Lys Lys Met Ser Gly Pro Leu
                 620                 625                 630

 Gly Pro Glu Glu Ala Ser Pro Lys Pro Asp Asp Pro Cys Pro Glu
                 635                 640                 645

 Gly Trp Gln Ser Phe Pro Ala Ser Leu Ser Cys Tyr Lys Val Phe
                 650                 655                 660

 His Ala Glu Arg Ile Val Arg Lys Arg Asn Trp Glu Glu Ala Glu
                 665                 670                 675

 Arg Phe Cys Gln Ala Leu Gly Ala His Leu Ser Ser Phe Ser His
                 680                 685                 690

 Val Asp Glu Ile Lys Glu Phe Leu His Phe Leu Thr Asp Gln Phe
                 695                 700                 705

 Ser Gly Gln His Trp Leu Trp Ile Gly Leu Asn Lys Arg Ser Pro
                 710                 715                 720

 Asp Leu Gln Gly Ser Trp Gln Trp Ser Asp Arg Thr Pro Val Ser
                 725                 730                 735

 Thr Ile Ile Met Pro Asn Glu Phe Gln Gln Asp Tyr Asp Ile Arg
                 740                 745                 750

 Asp Cys Ala Ala Val Lys Val Phe His Arg Pro Trp Arg Arg Gly
                 755                 760                 765

 Trp His Phe Tyr Asp Asp Arg Glu Phe Ile Tyr Leu Arg Pro Phe
                 770                 775                 780

 Ala Cys Asp Thr Lys Leu Glu Trp Val Cys Gln Ile Pro Lys Gly
                 785                 790                 795

 Arg Thr Pro Lys Thr Pro Asp Trp Tyr Asn Pro Asp Arg Ala Gly
                 800                 805                 810

 Ile His Gly Pro Pro Leu Ile Ile Glu Gly Ser Glu Tyr Trp Phe
                 815                 820                 825

 Val Ala Asp Leu His Leu Asn Tyr Glu Glu Ala Val Leu Tyr Cys
                 830                 835                 840

 Ala Ser Asn His Ser Phe Leu Ala Thr Ile Thr Ser Phe Val Gly
                 845                 850                 855

 Leu Lys Ala Ile Lys Asn Lys Ile Ala Asn Ile Ser Gly Asp Gly
                 860                 865                 870

 Gln Lys Trp Trp Ile Arg Ile Ser Glu Trp Pro Ile Asp Asp His
                 875                 880                 885

 Phe Thr Tyr Ser Arg Tyr Pro Trp His Arg Phe Pro Val Thr Phe
                 890                 895                 900

 Gly Glu Glu Cys Leu Tyr Met Ser Ala Lys Thr Trp Leu Ile Asp
                 905                 910                 915

 Leu Gly Lys Pro Thr Asp Cys Ser Thr Lys Leu Pro Phe Ile Cys
                 920                 925                 930

 Glu Lys Tyr Asn Val Ser Ser Leu Glu Lys Tyr Ser Pro Asp Ser
                 935                 940                 945

 Ala Ala Lys Val Gln Cys Ser Glu Gln Trp Ile Pro Phe Gln Asn
                 950                 955                 960

 Lys Cys Phe Leu Lys Ile Lys Pro Val Ser Leu Thr Phe Ser Gln
                 965                 970                 975

 Ala Ser Asp Thr Cys His Ser Tyr Gly Gly Thr Leu Pro Ser Val
                 980                 985                 990

 Leu Ser Gln Ile Glu Gln Asp Phe Ile Thr Ser Leu Leu Pro Asp
                 995                1000                1005

 Met Glu Ala Thr Leu Trp Ile Gly Leu Arg Trp Thr Ala Tyr Glu
                1010                1015                1020

 Lys Ile Asn Lys Trp Thr Asp Asn Arg Glu Leu Thr Tyr Ser Asn
                1025                1030                1035

 Phe His Pro Leu Leu Val Ser Gly Arg Leu Arg Ile Pro Glu Asn
                1040                1045                1050

 Phe Phe Glu Glu Glu Ser Arg Tyr His Cys Ala Leu Ile Leu Asn
                1055                1060                1065

 Leu Gln Lys Ser Pro Phe Thr Gly Thr Trp Asn Phe Thr Ser Cys
                1070                1075                1080

 Ser Glu Arg His Phe Val Ser Leu Cys Gln Lys Tyr Ser Glu Val
                1085                1090                1095

 Lys Ser Arg Gln Thr Leu Gln Asn Ala Ser Glu Thr Val Lys Tyr
                1100                1105                1110

 Leu Asn Asn Leu Tyr Lys Ile Ile Pro Lys Thr Leu Thr Trp His
                1115                1120                1125

 Ser Ala Lys Arg Glu Cys Leu Lys Ser Asn Met Gln Leu Val Ser
                1130                1135                1140

 Ile Thr Asp Pro Tyr Gln Gln Ala Phe Leu Ser Val Gln Ala Leu
                1145                1150                1155

 Leu His Asn Ser Ser Leu Trp Ile Gly Leu Phe Ser Gln Asp Asp
                1160                1165                1170

 Glu Leu Asn Phe Gly Trp Ser Asp Gly Lys Arg Leu His Phe Ser
                1175                1180                1185

 Arg Trp Ala Glu Thr Asn Gly Gln Leu Glu Asp Cys Val Val Leu
                1190                1195                1200

 Asp Thr Asp Gly Phe Trp Lys Thr Val Asp Cys Asn Asp Asn Gln
                1205                1210                1215

 Pro Gly Ala Ile Cys Tyr Tyr Ser Gly Asn Glu Thr Glu Lys Glu
                1220                1225                1230

 Val Lys Pro Val Asp Ser Val Lys Cys Pro Ser Pro Val Leu Asn
                1235                1240                1245

 Thr Pro Trp Ile Pro Phe Gln Asn Cys Cys Tyr Asn Phe Ile Ile
                1250                1255                1260

 Thr Lys Asn Arg His Met Ala Thr Thr Gln Asp Glu Val His Thr
                1265                1270                1275

 Lys Cys Gln Lys Leu Asn Pro Lys Ser His Ile Leu Ser Ile Arg
                1280                1285                1290

 Asp Glu Lys Glu Asn Asn Phe Val Leu Glu Gln Leu Leu Tyr Phe
                1295                1300                1305

 Asn Tyr Met Ala Ser Trp Val Met Leu Gly Ile Thr Tyr Arg Asn
                1310                1315                1320

 Asn Ser Leu Met Trp Phe Asp Lys Thr Pro Leu Ser Tyr Thr His
                1325                1330                1335

 Trp Arg Ala Gly Arg Pro Thr Ile Lys Asn Glu Lys Phe Leu Ala
                1340                1345                1350

 Gly Leu Ser Thr Asp Gly Phe Trp Asp Ile Gln Thr Phe Lys Val
                1355                1360                1365

 Ile Glu Glu Ala Val Tyr Phe His Gln His Ser Ile Leu Ala Cys
                1370                1375                1380

 Lys Ile Glu Met Val Asp Tyr Lys Glu Glu His Asn Thr Thr Leu
                1385                1390                1395

 Pro Gln Phe Met Pro Tyr Glu Asp Gly Ile Tyr Ser Val Ile Gln
                1400                1405                1410

 Lys Lys Val Thr Trp Tyr Glu Ala Leu Asn Met Cys Ser Gln Ser
                1415                1420                1425

 Gly Gly His Leu Ala Ser Val His Asn Gln Asn Gly Gln Leu Phe
                1430                1435                1440

 Leu Glu Asp Ile Val Lys Arg Asp Gly Phe Pro Leu Trp Val Gly
                1445                1450                1455

 Leu Ser Ser His Asp Gly Ser Glu Ser Ser Phe Glu Trp Ser Asp
                1460                1465                1470

 Gly Ser Thr Phe Asp Tyr Ile Pro Trp Lys Gly Gln Thr Ser Pro
                1475                1480                1485

 Gly Asn Cys Val Leu Leu Asp Pro Lys Gly Thr Trp Lys His Glu
                1490                1495                1500

 Lys Cys Asn Ser Val Lys Asp Gly Ala Ile Cys Tyr Lys Pro Thr
                1505                1510                1515

 Lys Ser Lys Lys Leu Ser Arg Leu Thr Tyr Ser Ser Arg Cys Pro
                1520                1525                1530

 Ala Ala Lys Glu Asn Gly Ser Arg Trp Ile Gln Tyr Lys Gly His
                1535                1540                1545

 Cys Tyr Lys Ser Asp Gln Ala Leu His Ser Phe Ser Glu Ala Lys
                1550                1555                1560

 Lys Leu Cys Ser Lys His Asp His Ser Ala Thr Ile Val Ser Ile
                1565                1570                1575

 Lys Asp Glu Asp Glu Asn Lys Phe Val Ser Arg Leu Met Arg Glu
                1580                1585                1590

 Asn Asn Asn Ile Thr Met Arg Val Trp Leu Gly Leu Ser Gln His
                1595                1600                1605

 Ser Val Asp Gln Ser Trp Ser Trp Leu Asp Gly Ser Glu Val Thr
                1610                1615                1620

 Phe Val Lys Trp Glu Asn Lys Ser Lys Ser Gly Val Gly Arg Cys
                1625                1630                1635

 Ser Met Leu Ile Ala Ser Asn Glu Thr Trp Lys Lys Val Glu Cys
                1640                1645                1650

 Glu His Gly Phe Gly Arg Val Val Cys Lys Val Pro Leu Gly Pro
                1655                1660                1665

 Asp Tyr Thr Ala Ile Ala Ile Ile Val Ala Thr Leu Ser Ile Leu
                1670                1675                1680

 Val Leu Met Gly Gly Leu Ile Trp Phe Leu Phe Gln Arg His Arg
                1685                1690                1695

 Leu His Leu Ala Gly Phe Ser Ser Val Arg Tyr Ala Gln Gly Val
                1700                1705                1710

 Asn Glu Asp Glu Ile Met Leu Pro Ser Phe His Asp
                1715                1720

<210> 5490
<211> 2298
<212> DNA
<213> Homo sapien

<400> 5490
 tcggccgagc ccagagacag ccagttcctc tcccgccgcg ccgggccgcg 50

 tgccgctcgc tccccggccg tggcgcctcc gggccagacg cgctgcagcc 100

 tccagcccgc ggcaagcggg cggggcggcc gcgccacccc cggccccgcg 150

 ccagcagccc ctcgccgcgc gtccagcgtt cccggccagc agcctcccca 200

 tacgcagtcc tgctggaccg ccccgtcgcg ccccccactc tgaactcaag 250

 tcaccgtgga gctccgccgc cccgaaactt tcacgcgagc gggaaatatg 300

 ggatgtataa aatcaaaagg gaaagacagc ttgagtgacg atggagtaga 350

 tttgaagact caaccagtac gtaatactga aagaactatt tatgtgagag 400

 atccaacgtc caataaacag caaaggccag ttccagaatc tcagctttta 450

 cctggacaga ggtttcaaac taaagatcca gaggaacaag gagacattgt 500

 ggtagccttg tacccctatg atggcatcca cccggacgac ttgtctttca 550

 agaaaggaga gaagatgaaa gtcctggagg agcatggaga atggtggaaa 600

 gcaaagtccc ttttaacaaa aaaagaaggc ttcatcccca gcaactatgt 650

 ggccaaactc aacaccttag aaacagaaga gtggtttttc aaggatataa 700

 ccaggaagga cgcagaaagg cagcttttgg caccaggaaa tagcgctgga 750

 gctttcctta ttagagaaag tgaaacatta aaaggaagct tctctctgtc 800

 tgtcagagac tttgaccctg tgcatggtga tgttattaag cactacaaaa 850

 ttagaagtct ggataatggg ggctattaca tctctccacg aatcactttt 900

 ccctgtatca gcgacatgat taaacattac caaaagcagg cagatggctt 950

 gtgcagaaga ttggagaagg cttgtattag tcccaagcca cagaagccat 1000

 gggataaaga tgcctgggag atcccccggg agtccatcaa gttggtgaaa 1050

 aggcttggcg ctgggcagtt tggggaagtc tggatgggtt actataacaa 1100

 cagtaccaag gtggctgtga aaaccctgaa gccaggaact atgtctgtgc 1150

 aagccttcct ggaagaagcc aacctcatga agaccctgca gcatgacaag 1200

 ctcgtgaggc tctacgctgt ggtcaccagg gaggagccca tttacatcat 1250

 caccgagtac atggccaagg gcagtttgct ggatttcctg aagagcgatg 1300

 aaggtggcaa agtgctgctt ccaaagctca ttgacttttc tgctcagatt 1350

 gcagagggaa tggcatacat cgagcggaag aactacattc accgggacct 1400

 gcgagcagct aatgttctgg tctccgagtc actaatgtgc aaaattgcag 1450

 attttggcct tgctagagta attgaagata atgagtacac agcaagggaa 1500

 ggtgctaagt tccctattaa gtggacggct ccagaagcaa tcaactttgg 1550

 atgtttcact attaagtctg atgtgtggtc ctttggaatc ctcctatacg 1600

 aaattgtcac ctatgggaaa attccctacc cagggagaac taatgccgac 1650

 gtgatgaccg ccctgtccca gggctacagg atgccccgtg tggagaactg 1700

 cccagatgag ctctatgaca ttatgaaaat gtgctggaaa gaaaaggcag 1750

 aagagagacc aacgtttgac tacttacaga gcgtcctgga tgatttctac 1800

 acagccacgg aagggcaata ccagcagcag ccttagagca cagggagacc 1850

 cgtccatttg gcaggggtgg ctgcctcatt tagagaggaa aagtaaccat 1900

 cactggttgc acttatgatt tcatgtgcgg ggatcatctg ccgtgcctgg 1950

 atcctgaaat agaggctaaa ttactcagga agaacaccct ctaaatggga 2000

 aagtattctg tactcttaga tggattctcc actcagttgc aacttggact 2050

 tgtcctcagc agctggtaat cttgctctgc ttgacaacat ctgagtgcag 2100

 ccgtttgaga agaaaacatc tattctctcc aaaaatgcac ccaactagct 2150

 ctatgtttac aaatggacat aggactcaaa gtttcagaga ccattgcaat 2200

 gaatccccaa taattgcaga actaaactca tttataaagc taaaataacc 2250

 ggatatatac atagcatgac atttctttgt gctttggctt acttgttt 2298

<210> 5491
<211> 512
<212> PRT
<213> Homo sapien

<400> 5491
 Met Gly Cys Ile Lys Ser Lys Gly Lys Asp Ser Leu Ser Asp Asp
   1               5                  10                  15

 Gly Val Asp Leu Lys Thr Gln Pro Val Arg Asn Thr Glu Arg Thr
                  20                  25                  30

 Ile Tyr Val Arg Asp Pro Thr Ser Asn Lys Gln Gln Arg Pro Val
                  35                  40                  45

 Pro Glu Ser Gln Leu Leu Pro Gly Gln Arg Phe Gln Thr Lys Asp
                  50                  55                  60

 Pro Glu Glu Gln Gly Asp Ile Val Val Ala Leu Tyr Pro Tyr Asp
                  65                  70                  75

 Gly Ile His Pro Asp Asp Leu Ser Phe Lys Lys Gly Glu Lys Met
                  80                  85                  90

 Lys Val Leu Glu Glu His Gly Glu Trp Trp Lys Ala Lys Ser Leu
                  95                 100                 105

 Leu Thr Lys Lys Glu Gly Phe Ile Pro Ser Asn Tyr Val Ala Lys
                 110                 115                 120

 Leu Asn Thr Leu Glu Thr Glu Glu Trp Phe Phe Lys Asp Ile Thr
                 125                 130                 135

 Arg Lys Asp Ala Glu Arg Gln Leu Leu Ala Pro Gly Asn Ser Ala
                 140                 145                 150

 Gly Ala Phe Leu Ile Arg Glu Ser Glu Thr Leu Lys Gly Ser Phe
                 155                 160                 165

 Ser Leu Ser Val Arg Asp Phe Asp Pro Val His Gly Asp Val Ile
                 170                 175                 180

 Lys His Tyr Lys Ile Arg Ser Leu Asp Asn Gly Gly Tyr Tyr Ile
                 185                 190                 195

 Ser Pro Arg Ile Thr Phe Pro Cys Ile Ser Asp Met Ile Lys His
                 200                 205                 210

 Tyr Gln Lys Gln Ala Asp Gly Leu Cys Arg Arg Leu Glu Lys Ala
                 215                 220                 225

 Cys Ile Ser Pro Lys Pro Gln Lys Pro Trp Asp Lys Asp Ala Trp
                 230                 235                 240

 Glu Ile Pro Arg Glu Ser Ile Lys Leu Val Lys Arg Leu Gly Ala
                 245                 250                 255

 Gly Gln Phe Gly Glu Val Trp Met Gly Tyr Tyr Asn Asn Ser Thr
                 260                 265                 270

 Lys Val Ala Val Lys Thr Leu Lys Pro Gly Thr Met Ser Val Gln
                 275                 280                 285

 Ala Phe Leu Glu Glu Ala Asn Leu Met Lys Thr Leu Gln His Asp
                 290                 295                 300

 Lys Leu Val Arg Leu Tyr Ala Val Val Thr Arg Glu Glu Pro Ile
                 305                 310                 315

 Tyr Ile Ile Thr Glu Tyr Met Ala Lys Gly Ser Leu Leu Asp Phe
                 320                 325                 330

 Leu Lys Ser Asp Glu Gly Gly Lys Val Leu Leu Pro Lys Leu Ile
                 335                 340                 345

 Asp Phe Ser Ala Gln Ile Ala Glu Gly Met Ala Tyr Ile Glu Arg
                 350                 355                 360

 Lys Asn Tyr Ile His Arg Asp Leu Arg Ala Ala Asn Val Leu Val
                 365                 370                 375

 Ser Glu Ser Leu Met Cys Lys Ile Ala Asp Phe Gly Leu Ala Arg
                 380                 385                 390

 Val Ile Glu Asp Asn Glu Tyr Thr Ala Arg Glu Gly Ala Lys Phe
                 395                 400                 405

 Pro Ile Lys Trp Thr Ala Pro Glu Ala Ile Asn Phe Gly Cys Phe
                 410                 415                 420

 Thr Ile Lys Ser Asp Val Trp Ser Phe Gly Ile Leu Leu Tyr Glu
                 425                 430                 435

 Ile Val Thr Tyr Gly Lys Ile Pro Tyr Pro Gly Arg Thr Asn Ala
                 440                 445                 450

 Asp Val Met Thr Ala Leu Ser Gln Gly Tyr Arg Met Pro Arg Val
                 455                 460                 465

 Glu Asn Cys Pro Asp Glu Leu Tyr Asp Ile Met Lys Met Cys Trp
                 470                 475                 480

 Lys Glu Lys Ala Glu Glu Arg Pro Thr Phe Asp Tyr Leu Gln Ser
                 485                 490                 495

 Val Leu Asp Asp Phe Tyr Thr Ala Thr Glu Gly Gln Tyr Gln Gln
                 500                 505                 510

 Gln Pro


<210> 5492
<211> 1056
<212> DNA
<213> Homo sapien

<400> 5492
 gtctgcgcgg agtctgagcg gcgctcgtcc cgtcccaagg ccgacgccag 50

 cacgccgtca tggcccccgc agcggcgacg gggggcagca ccctgcccag 100

 tggcttctcg gtcttcacca ccttgcccga cttgctcttc atctttgagt 150

 ttatcttcgg gggcctggtg tggatcctgg tggcctcctc cctggtgccc 200

 tggcccctgg tccagggctg ggtgatgttc gtgtctgtgt tctgcttcgt 250

 ggccaccacc accttgatca tcctgtacat aattggagcc cacggtggag 300

 agacttcctg ggtcaccttg gacgcagcct accactgcac cgctgccctc 350

 ttttacctca gcgcctcagt cctggaggcc ctggccacca tcacgatgca 400

 agacggcttc acctacaggc actaccatga aaacattgct gccgtggtgt 450

 tctcctacat agccactctg ctctacgtgg tccatgcggt gttctcttta 500

 atcagatgga agtcttcata aagccgcagt agaacttgag ctgaaaaccc 550

 agatggtgtt aactggccgc cccactttcc ggcataactt tttagaaaac 600

 agaaatgccc ttgatggtgg aaaaaagaaa acaaccaccc ccccactgcc 650

 caaaaaaaaa agccctgccc tgttgctcgt gggtgctgtg tttactctcc 700

 cgtgtgcctt cgcgtccggg ttgggagctt gctgtgtcta acctccaact 750

 gctgtgctgt ctgctagggt cacctcctgt ttgtgaaagg ggaccttctt 800

 gttcgggggt gggaagtggc gaccgtgacc tgagaaggaa agaaagatcc 850

 tctgctgacc cctggagcag ctctcgagaa ctacctgttg gtattgtcca 900

 caagctctcc cgagcgcccc atcttgtgcc atgttttaag tcttcatgga 950

 tgttctgcat gtcatgggga ctaaaactca cccaacagat ctttccagag 1000

 gtccatggtg gaagacgata accctgtgaa atactttata aaatgtctta 1050

 atgttc 1056

<210> 5493
<211> 153
<212> PRT
<213> Homo sapien

<400> 5493
 Met Ala Pro Ala Ala Ala Thr Gly Gly Ser Thr Leu Pro Ser Gly
   1               5                  10                  15

 Phe Ser Val Phe Thr Thr Leu Pro Asp Leu Leu Phe Ile Phe Glu
                  20                  25                  30

 Phe Ile Phe Gly Gly Leu Val Trp Ile Leu Val Ala Ser Ser Leu
                  35                  40                  45

 Val Pro Trp Pro Leu Val Gln Gly Trp Val Met Phe Val Ser Val
                  50                  55                  60

 Phe Cys Phe Val Ala Thr Thr Thr Leu Ile Ile Leu Tyr Ile Ile
                  65                  70                  75

 Gly Ala His Gly Gly Glu Thr Ser Trp Val Thr Leu Asp Ala Ala
                  80                  85                  90

 Tyr His Cys Thr Ala Ala Leu Phe Tyr Leu Ser Ala Ser Val Leu
                  95                 100                 105

 Glu Ala Leu Ala Thr Ile Thr Met Gln Asp Gly Phe Thr Tyr Arg
                 110                 115                 120

 His Tyr His Glu Asn Ile Ala Ala Val Val Phe Ser Tyr Ile Ala
                 125                 130                 135

 Thr Leu Leu Tyr Val Val His Ala Val Phe Ser Leu Ile Arg Trp
                 140                 145                 150

 Lys Ser Ser


<210> 5494
<211> 3371
<212> DNA
<213> Homo sapien

<400> 5494
 gctcgggcca cgcccacctg tcctgcagca ctggatgctt tgtgagttgg 50

 ggattgttgc gtcccatatc tggacccaga agggacttcc ctgctcggct 100

 ggctctcggt ttctctgctt tcctccggag aaataacagc gtcttccgcg 150

 ccgcgcatgg agcctcccgg ccgccgcgag tgtccctttc cttcctggcg 200

 ctttcctggg ttgcttctgg cggccatggt gttgctgctg tactccttct 250

 ccgatgcctg tgaggagcca ccaacatttg aagctatgga gctcattggt 300

 aaaccaaaac cctactatga gattggtgaa cgagtagatt ataagtgtaa 350

 aaaaggatac ttctatatac ctcctcttgc cacccatact atttgtgatc 400

 ggaatcatac atggctacct gtctcagatg acgcctgtta tagagaaaca 450

 tgtccatata tacgggatcc tttaaatggc caagcagtcc ctgcaaatgg 500

 gacttacgag tttggttatc agatgcactt tatttgtaat gagggttatt 550

 acttaattgg tgaagaaatt ctatattgtg aacttaaagg atcagtagca 600

 atttggagcg gtaagccccc aatatgtgaa aaggttttgt gtacaccacc 650

 tccaaaaata aaaaatggaa aacacacctt tagtgaagta gaagtatttg 700

 agtatcttga tgcagtaact tatagttgtg atcctgcacc tggaccagat 750

 ccattttcac ttattggaga gagcacgatt tattgtggtg acaattcagt 800

 gtggagtcgt gctgctccag agtgtaaagt ggtcaaatgt cgatttccag 850

 tagtcgaaaa tggaaaacag atatcaggat ttggaaaaaa attttactac 900

 aaagcaacag ttatgtttga atgcgataag ggtttttacc tcgatggcag 950

 cgacacaatt gtctgtgaca gtaacagtac ttgggatccc ccagttccaa 1000

 agtgtcttaa agtgctgcct ccatctagta caaaacctcc agctttgagt 1050

 cattcagtgt cgacttcttc cactacaaaa tctccagcgt ccagtgcctc 1100

 aggtcctagg cctacttaca agcctccagt ctcaaattat ccaggatatc 1150

 ctaaacctga ggaaggaata cttgacagtt tggatgtttg ggtcattgct 1200

 gtgattgtta ttgccatagt tgttggagtt gcagtaattt gtgttgtccc 1250

 gtacagatat cttcaaagga ggaagaagaa aggcacatac ctaactgatg 1300

 agacccacag agaagtaaaa tttacttctc tctgagaagg agagatgaga 1350

 gaaaggtttg cttttatcat taaaaggaaa gcagatggtg gagctgaata 1400

 tgccacttac cagactaaat caaccactcc agcagagcag agaggctgaa 1450

 tagattccac aacctggttt gccagttcat cttttgactc tattaaaatc 1500

 ttcaatagtt gttattctgt agtttcactc tcatgagtgc aactgtggct 1550

 tagctaatat tgcaatgtgg cttgaatgta ggtagcatcc tttgatgctt 1600

 ctttgaaact tgtatgaatt tgggtatgaa cagattgcct gctttccctt 1650

 aaataacact tagatttatt ggaccagtca gcacagcatg cctggttgta 1700

 ttaaagcagg gatatgctgt attttataaa attggcaaaa ttagagaaat 1750

 atagttcaca atgaaattat attttctttg taaagaaagt ggcttgaaat 1800

 cttttttgtt caaagattaa tgccaactct taagattatt ctttcaccaa 1850

 ctatagaatg tattttatat atcgttcatt gtaaaaagcc cttaaaaata 1900

 tgtgtatact actttggctc ttgtgcataa aaacaagaac actgaaaatt 1950

 gggaatatgc acaaacttgg cttctttaac caagaatatt attggaaaat 2000

 tctctaaaag ttaatagggt aaattctcta ttttttgtaa tgtgttcggt 2050

 gatttcagaa agctagaaag tgtatgtgtg gcatttgttt tcacttttta 2100

 aaacatccct aactgatcga atatatcagt aatttcagaa tcagatgcat 2150

 cctttcataa gaagtgagag gactctgaca gccataacag gagtgccact 2200

 tcatggtgcg aagtgaacac tgtagtcttg ttgttttccc aaagagaact 2250

 ccgtatgttc tcttaggttg agtaacccac tctgaattct ggttacatgt 2300

 gtttttctct ccctccttaa ataaagagag gggttaaaca tgccctctaa 2350

 aagtaggtgg ttttgaagag aataaattca tcagataacc tcaagtcaca 2400

 tgagaatctt agtccattta cattgccttg gctagtaaaa gccatctatg 2450

 tatatgtctt acctcatctc ctaaaaggca gagtacaaag taagccatgt 2500

 atctcaggaa ggtaacttca ttttgtctat ttgctgttga ttgtaccaag 2550

 ggatggaaga agtaaatata gctcaggtag cactttatac tcaggcagat 2600

 ctcagccctc tactgagtcc cttagccaag cagtttcttt caaagaagcc 2650

 agcaggcgaa aagcagggac tgccactgca tttcatatca cactgttaaa 2700

 agttgtgttt tgaaatttta tgtttagttg cacaaattgg gccaaagaaa 2750

 cattgccttg aggaagatat gattggaaaa tcaagagtgt agaagaataa 2800

 atactgtttt actgtccaaa gacatgttta tagtgctctg taaatgttcc 2850

 tttcctttgt agtctctggc aagatgcttt aggaagataa aagtttgagg 2900

 agaacaaaca ggaattctga attaagcaca gagttgaagt ttatacccgt 2950

 ttcacatgct tttcaagaat gtcgcaatta ctaagaagca gataatggtg 3000

 ttttttagaa acctaattga agtatattca accaaatact ttaatgtata 3050

 aaataaatat tatacaatat acttgtatag cagtttctgc ttcacatttg 3100

 attttttcaa atttaatatt tatattagag atctatatat gtataaatat 3150

 gtattttgtc aaatttgtta cttaaatata tagagaccag ttttctctgg 3200

 aagtttgttt aaatgacaga agcgtatatg aattcaagaa aatttaagct 3250

 gcaaaaatgt atttgctata aaatgagaag tctcactgat agaggttctt 3300

 tattgctcat tttttaaaaa atggactctt gaaatctgtt aaaataaaat 3350

 tgtacatttg gagatgtttc a 3371

<210> 5495
<211> 392
<212> PRT
<213> Homo sapien

<400> 5495
 Met Glu Pro Pro Gly Arg Arg Glu Cys Pro Phe Pro Ser Trp Arg
   1               5                  10                  15

 Phe Pro Gly Leu Leu Leu Ala Ala Met Val Leu Leu Leu Tyr Ser
                  20                  25                  30

 Phe Ser Asp Ala Cys Glu Glu Pro Pro Thr Phe Glu Ala Met Glu
                  35                  40                  45

 Leu Ile Gly Lys Pro Lys Pro Tyr Tyr Glu Ile Gly Glu Arg Val
                  50                  55                  60

 Asp Tyr Lys Cys Lys Lys Gly Tyr Phe Tyr Ile Pro Pro Leu Ala
                  65                  70                  75

 Thr His Thr Ile Cys Asp Arg Asn His Thr Trp Leu Pro Val Ser
                  80                  85                  90

 Asp Asp Ala Cys Tyr Arg Glu Thr Cys Pro Tyr Ile Arg Asp Pro
                  95                 100                 105

 Leu Asn Gly Gln Ala Val Pro Ala Asn Gly Thr Tyr Glu Phe Gly
                 110                 115                 120

 Tyr Gln Met His Phe Ile Cys Asn Glu Gly Tyr Tyr Leu Ile Gly
                 125                 130                 135

 Glu Glu Ile Leu Tyr Cys Glu Leu Lys Gly Ser Val Ala Ile Trp
                 140                 145                 150

 Ser Gly Lys Pro Pro Ile Cys Glu Lys Val Leu Cys Thr Pro Pro
                 155                 160                 165

 Pro Lys Ile Lys Asn Gly Lys His Thr Phe Ser Glu Val Glu Val
                 170                 175                 180

 Phe Glu Tyr Leu Asp Ala Val Thr Tyr Ser Cys Asp Pro Ala Pro
                 185                 190                 195

 Gly Pro Asp Pro Phe Ser Leu Ile Gly Glu Ser Thr Ile Tyr Cys
                 200                 205                 210

 Gly Asp Asn Ser Val Trp Ser Arg Ala Ala Pro Glu Cys Lys Val
                 215                 220                 225

 Val Lys Cys Arg Phe Pro Val Val Glu Asn Gly Lys Gln Ile Ser
                 230                 235                 240

 Gly Phe Gly Lys Lys Phe Tyr Tyr Lys Ala Thr Val Met Phe Glu
                 245                 250                 255

 Cys Asp Lys Gly Phe Tyr Leu Asp Gly Ser Asp Thr Ile Val Cys
                 260                 265                 270

 Asp Ser Asn Ser Thr Trp Asp Pro Pro Val Pro Lys Cys Leu Lys
                 275                 280                 285

 Val Leu Pro Pro Ser Ser Thr Lys Pro Pro Ala Leu Ser His Ser
                 290                 295                 300

 Val Ser Thr Ser Ser Thr Thr Lys Ser Pro Ala Ser Ser Ala Ser
                 305                 310                 315

 Gly Pro Arg Pro Thr Tyr Lys Pro Pro Val Ser Asn Tyr Pro Gly
                 320                 325                 330

 Tyr Pro Lys Pro Glu Glu Gly Ile Leu Asp Ser Leu Asp Val Trp
                 335                 340                 345

 Val Ile Ala Val Ile Val Ile Ala Ile Val Val Gly Val Ala Val
                 350                 355                 360

 Ile Cys Val Val Pro Tyr Arg Tyr Leu Gln Arg Arg Lys Lys Lys
                 365                 370                 375

 Gly Thr Tyr Leu Thr Asp Glu Thr His Arg Glu Val Lys Phe Thr
                 380                 385                 390

 Ser Leu


<210> 5496
<211> 1861
<212> DNA
<213> Homo sapien

<400> 5496
 ggggggggag atgcagtagc cgaaaactgc gcggaggcac gagaggccgg 50

 ggagagcgtt ctgggtccga gggtccaggt aggggttgag ccaccatctg 100

 accgcaagct gcgtcgtgtc gccttctctg caggcaccat gagccaggac 150

 accgaggtgg atatgaagga ggtggagctg aatgagttag agcccgagaa 200

 gcagccgatg aacgcggcgt ctggggcggc catgtccctg gcggaagccg 250

 agaagaatgg tctggtgaag atcaaggtgg cggaagacga ggcggaggcg 300

 gcagccgcgg ctaagttcac gggcctgtcc aaggaggagc tgctgaaggt 350

 ggcaggcagc cccggctggg tacgcacccg ctgggcactg ctgctgctct 400

 tctggctcgg ctggctcggc atgcttgctg gtgccgtggt gataatcgtg 450

 cgagcgccgc gttgtcgcga gctaccggcg cagaagtggt ggcacacggg 500

 ccccctctac cgcatcggcg accttcaggc cttccagggc cacggcgcgg 550

 gcaacctggc gggtctgaag gggcgtctcg attacctgag ctctctgaag 600

 gtgaagggcc ttgtgctggg tccaattcac aagaaccaga aggatgatgt 650

 cgctcagact gacttgctgc agatcgaccc caattttggc tccaaggaag 700

 attttgacag tctcttgcaa tcggctaaaa aaaagagcat ccgtgtcatt 750

 ctggacctta ctcccaacta ccggggtgac aactcgtggt tctccactca 800

 ggttgacact gtggccacca aggtgaagga tgctctggag ttttggctgc 850

 aagctggcgt ggatgggttc caggttcggg acatagagaa tctgaaggat 900

 gcatcctcat tcttggctga gtggcaaaat atcaccaagg gcttcagtgg 950

 agacaggctc ttgattgcgg ggactaactc ctccgacctt cagcagatcc 1000

 tgagcctact cgaatccaac aaagacttgc tgttgactag ctcatacctg 1050

 tctgattctg gttctactcc ccagcataca aaatccctag tcacacagta 1100

 tttgaatgcc actggcaatc gctggtgcag ctggagtttg tctcaggcaa 1150

 ggctcctgac ttccttcttg ccggctcaac ttctccgact ctaccagctg 1200

 atgctcttca ccctgccagg gacccctctt ttcagctacg gggatgagat 1250

 tggcctggat gcagctgccc ttcctccaca gcctatggag gctccagtca 1300

 tgctgtggga tgagtccagc ttccctgaca tcccaggggc tgtaagtgcc 1350

 aacatgactg tgaagggcca gagtgaagac cctggctccc tcctttcctt 1400

 gttccggcgg ctgagtgacc agcggagtaa ggagcgctcc ctactgcatg 1450

 gggacttcca cgcgttctcc gctgggcctg gactcttctc ctatatccgc 1500

 cactgggacc agaatgagcg ttttctggta gtgcttaact ttggggatgt 1550

 gggcctctcg gctggactgc aggcctccga cctgcctgcc agcgccagcc 1600

 tgccagccaa ggctgacctc ctgctcagca cccagccagg ccgtgaggag 1650

 ggctcccctc ctgagctggg acgcctgaaa ctggagcctc acgaagggct 1700

 gctgctccgc ttcccctacg cggcctgacc tcagcctgac atggacccac 1750

 tacccttctc ctttccttcc caggcccttt ggcttctgat tttttttctc 1800

 ttttttaaaa caaacaaaca aactgttgca gattatgagt gaaccccaaa 1850

 tagggtgttt t 1861

<210> 5497
<211> 529
<212> PRT
<213> Homo sapien

<400> 5497
 Met Ser Gln Asp Thr Glu Val Asp Met Lys Glu Val Glu Leu Asn
   1               5                  10                  15

 Glu Leu Glu Pro Glu Lys Gln Pro Met Asn Ala Ala Ser Gly Ala
                  20                  25                  30

 Ala Met Ser Leu Ala Glu Ala Glu Lys Asn Gly Leu Val Lys Ile
                  35                  40                  45

 Lys Val Ala Glu Asp Glu Ala Glu Ala Ala Ala Ala Ala Lys Phe
                  50                  55                  60

 Thr Gly Leu Ser Lys Glu Glu Leu Leu Lys Val Ala Gly Ser Pro
                  65                  70                  75

 Gly Trp Val Arg Thr Arg Trp Ala Leu Leu Leu Leu Phe Trp Leu
                  80                  85                  90

 Gly Trp Leu Gly Met Leu Ala Gly Ala Val Val Ile Ile Val Arg
                  95                 100                 105

 Ala Pro Arg Cys Arg Glu Leu Pro Ala Gln Lys Trp Trp His Thr
                 110                 115                 120

 Gly Pro Leu Tyr Arg Ile Gly Asp Leu Gln Ala Phe Gln Gly His
                 125                 130                 135

 Gly Ala Gly Asn Leu Ala Gly Leu Lys Gly Arg Leu Asp Tyr Leu
                 140                 145                 150

 Ser Ser Leu Lys Val Lys Gly Leu Val Leu Gly Pro Ile His Lys
                 155                 160                 165

 Asn Gln Lys Asp Asp Val Ala Gln Thr Asp Leu Leu Gln Ile Asp
                 170                 175                 180

 Pro Asn Phe Gly Ser Lys Glu Asp Phe Asp Ser Leu Leu Gln Ser
                 185                 190                 195

 Ala Lys Lys Lys Ser Ile Arg Val Ile Leu Asp Leu Thr Pro Asn
                 200                 205                 210

 Tyr Arg Gly Asp Asn Ser Trp Phe Ser Thr Gln Val Asp Thr Val
                 215                 220                 225

 Ala Thr Lys Val Lys Asp Ala Leu Glu Phe Trp Leu Gln Ala Gly
                 230                 235                 240

 Val Asp Gly Phe Gln Val Arg Asp Ile Glu Asn Leu Lys Asp Ala
                 245                 250                 255

 Ser Ser Phe Leu Ala Glu Trp Gln Asn Ile Thr Lys Gly Phe Ser
                 260                 265                 270

 Gly Asp Arg Leu Leu Ile Ala Gly Thr Asn Ser Ser Asp Leu Gln
                 275                 280                 285

 Gln Ile Leu Ser Leu Leu Glu Ser Asn Lys Asp Leu Leu Leu Thr
                 290                 295                 300

 Ser Ser Tyr Leu Ser Asp Ser Gly Ser Thr Pro Gln His Thr Lys
                 305                 310                 315

 Ser Leu Val Thr Gln Tyr Leu Asn Ala Thr Gly Asn Arg Trp Cys
                 320                 325                 330

 Ser Trp Ser Leu Ser Gln Ala Arg Leu Leu Thr Ser Phe Leu Pro
                 335                 340                 345

 Ala Gln Leu Leu Arg Leu Tyr Gln Leu Met Leu Phe Thr Leu Pro
                 350                 355                 360

 Gly Thr Pro Leu Phe Ser Tyr Gly Asp Glu Ile Gly Leu Asp Ala
                 365                 370                 375

 Ala Ala Leu Pro Pro Gln Pro Met Glu Ala Pro Val Met Leu Trp
                 380                 385                 390

 Asp Glu Ser Ser Phe Pro Asp Ile Pro Gly Ala Val Ser Ala Asn
                 395                 400                 405

 Met Thr Val Lys Gly Gln Ser Glu Asp Pro Gly Ser Leu Leu Ser
                 410                 415                 420

 Leu Phe Arg Arg Leu Ser Asp Gln Arg Ser Lys Glu Arg Ser Leu
                 425                 430                 435

 Leu His Gly Asp Phe His Ala Phe Ser Ala Gly Pro Gly Leu Phe
                 440                 445                 450

 Ser Tyr Ile Arg His Trp Asp Gln Asn Glu Arg Phe Leu Val Val
                 455                 460                 465

 Leu Asn Phe Gly Asp Val Gly Leu Ser Ala Gly Leu Gln Ala Ser
                 470                 475                 480

 Asp Leu Pro Ala Ser Ala Ser Leu Pro Ala Lys Ala Asp Leu Leu
                 485                 490                 495

 Leu Ser Thr Gln Pro Gly Arg Glu Glu Gly Ser Pro Pro Glu Leu
                 500                 505                 510

 Gly Arg Leu Lys Leu Glu Pro His Glu Gly Leu Leu Leu Arg Phe
                 515                 520                 525

 Pro Tyr Ala Ala


<210> 5498
<211> 670
<212> DNA
<213> Homo sapien

<400> 5498
 cggccacgag gcggaatccc ttctgctctc ccagcgcagc gccgccgccc 50

 ggcccctcca gcttcccgga ccatggccaa cctggagcgc accttcatcg 100

 ccatcaagcc ggacggcgtg cagcgcggcc tggtgggcga gatcatcaag 150

 cgcttcgagc agaagggatt ccgcctcgtg gccatgaagt tcctccgggc 200

 ctctgaagaa cacctgaagc agcactacat tgacctgaaa gaccgaccat 250

 tcttccctgg gctggtgaag tacatgaact cagggccggt tgtggccatg 300

 gtctgggagg ggctgaacgt ggtgaagaca ggccgagtga tgcttgggga 350

 gaccaatcca gcagattcaa agccaggcac cattcgtggg gacttctgca 400

 ttcaggttgg caggaacatc attcatggca gtgattcagt aaaaagtgct 450

 gaaaaagaaa tcagcctatg gtttaagcct gaagaactgg ttgactacaa 500

 gtcttgtgct catgactggg tctatgaata agaggtggac acaacagcag 550

 tctccttcag cacggcgtgg tgtgtccctg gacacagctc ttcattccat 600

 tgacttagag gcaacaggat tgatcattct tttatagagc atatttgcca 650

 ataaagcttt tggaagccgg 670

<210> 5499
<211> 152
<212> PRT
<213> Homo sapien

<400> 5499
 Met Ala Asn Leu Glu Arg Thr Phe Ile Ala Ile Lys Pro Asp Gly
   1               5                  10                  15

 Val Gln Arg Gly Leu Val Gly Glu Ile Ile Lys Arg Phe Glu Gln
                  20                  25                  30

 Lys Gly Phe Arg Leu Val Ala Met Lys Phe Leu Arg Ala Ser Glu
                  35                  40                  45

 Glu His Leu Lys Gln His Tyr Ile Asp Leu Lys Asp Arg Pro Phe
                  50                  55                  60

 Phe Pro Gly Leu Val Lys Tyr Met Asn Ser Gly Pro Val Val Ala
                  65                  70                  75

 Met Val Trp Glu Gly Leu Asn Val Val Lys Thr Gly Arg Val Met
                  80                  85                  90

 Leu Gly Glu Thr Asn Pro Ala Asp Ser Lys Pro Gly Thr Ile Arg
                  95                 100                 105

 Gly Asp Phe Cys Ile Gln Val Gly Arg Asn Ile Ile His Gly Ser
                 110                 115                 120

 Asp Ser Val Lys Ser Ala Glu Lys Glu Ile Ser Leu Trp Phe Lys
                 125                 130                 135

 Pro Glu Glu Leu Val Asp Tyr Lys Ser Cys Ala His Asp Trp Val
                 140                 145                 150

 Tyr Glu


<210> 5500
<211> 3547
<212> DNA
<213> Homo sapien

<400> 5500
 gcactcgccc ggctcgcccg ctttcgcacc cagttcacgc gccacagcta 50

 tgtgtccccg agccgcgcgg gcgcccgcga cgctactcct cgccctgggc 100

 gcggtgctgt ggcctgcggc tggcgcctgg gagcttacga ttttgcacac 150

 caacgacgtg cacagccggc tggagcagac cagcgaggac tccagcaagt 200

 gcgtcaacgc cagccgctgc atgggtggcg tggctcggct cttcaccaag 250

 gttcagcaga tccgccgcgc cgaacccaac gtgctgctgc tggacgccgg 300

 cgaccagtac cagggcacta tctggttcac cgtgtacaag ggcgccgagg 350

 tggcgcactt catgaacgcc ctgcgctacg atgccatggc actgggaaat 400

 catgaatttg ataatggtgt ggaaggactg atcgagccac tcctcaaaga 450

 ggccaaattt ccaattctga gtgcaaacat taaagcaaag gggccactag 500

 catctcaaat atcaggactt tatttgccat ataaagttct tcctgttggt 550

 gatgaagttg tgggaatcgt tggatacact tccaaagaaa ccccttttct 600

 ctcaaatcca gggacaaatt tagtgtttga agatgaaatc actgcattac 650

 aacctgaagt agataagtta aaaactctaa atgtgaacaa aattattgca 700

 ctgggacatt cgggttttga aatggataaa ctcatcgctc agaaagtgag 750

 gggtgtggac gtcgtggtgg gaggacactc caacacattt ctttacacag 800

 gcaatccacc ttccaaagag gtgcctgctg ggaagtaccc attcatagtc 850

 acttctgatg atgggcggaa ggttcctgta gtccaggcct atgcttttgg 900

 caaataccta ggctatctga agatcgagtt tgatgaaaga ggaaacgtca 950

 tctcttccca tggaaatccc attcttctaa acagcagcat tcctgaagat 1000

 ccaagcataa aagcagacat taacaaatgg aggataaaat tggataatta 1050

 ttctacccag gaattaggga aaacaattgt ctatctggat ggctcctctc 1100

 aatcatgccg ctttagagaa tgcaacatgg gcaacctgat ttgtgatgca 1150

 atgattaaca acaacctgag acacacggat gaaatgttct ggaaccacgt 1200

 atccatgtgc attttaaatg gaggtggtat ccggtcgccc attgatgaac 1250

 gcaacaatgg cacaattacc tgggagaacc tggctgctgt attgcccttt 1300

 ggaggcacat ttgacctagt ccagttaaaa ggttccaccc tgaagaaggc 1350

 ctttgagcat agcgtgcacc gctacggcca gtccactgga gagttcctgc 1400

 aggtgggcgg aatccatgtg gtgtatgatc tttcccgaaa acctggagac 1450

 agagtagtca aattagatgt tctttgcacc aagtgtcgag tgcccagtta 1500

 tgaccctctc aaaatggacg aggtatataa ggtgatcctc ccaaacttcc 1550

 tggccaatgg tggagatggg ttccagatga taaaagatga attattaaga 1600

 catgactctg gtgaccaaga tatcaacgtg gtttctacat atatctccaa 1650

 aatgaaagta atttatccag cagttgaagg tcggatcaag ttttccacag 1700

 gaagtcactg ccatggaagc ttttctttaa tatttctttc actttgggca 1750

 gtgatctttg ttttatacca atagccaaaa attctccttg cctttaatgt 1800

 gtgaaactgc attttttcaa gtgagattca aatctgcctt ttaggacctg 1850

 gctttgtgac agcaaaaacc atctttacag gctcctagaa gctgaaggtt 1900

 agagcattat aaaatgaaga gacagacatg attactcagg gtcagcaacc 1950

 tagtgagtta gaaaaaaaat taacataggg ccctataagg agaaagccaa 2000

 ctatgttaag tttacgtgtc caaattttaa tgaaatttta ctaacaattt 2050

 taaaccatat ttttcttctt catatccatt tctaatccat caaacagctt 2100

 atgtttacat aaaattttat cattcacaag gaagttttaa gcacactgtc 2150

 tcatttgata tccacaactt atttttggta ggaaagagag atgtttttcc 2200

 cacctgtcag atgaaaaaac tgaagctcaa aaagggttga cttgaccata 2250

 cagctaatgc tgacagatcc aagacctaga cctaggtctt ttgaactcaa 2300

 gtccagcatt ctcaactata tcaagttact gttcagaata cttaatatct 2350

 cctctcttca taattatcaa tagccccaag ctcatggatg acaaatctct 2400

 gctttatttc ttgtctctat tttttcactt tatagctcct gttataatag 2450

 caagtttaat ggtataaaca caggatacca tcctctcttg caacacccat 2500

 gtgcctttga tgagtcaggt agcaagctgt agtagataat gagaaaggcc 2550

 agaggctgca aagacagtca aaggacacga gagaaaggaa ggggaagaac 2600

 aggactccag gactgtttta tattatagaa aagcaagagc taaagagcat 2650

 ttacacatgt taaacagata cttgttaagc atagtgcctg acacacggca 2700

 ttagctgtta ttttatgaga ttccatcagc tctgcctctg tcctctttct 2750

 tctaacatga aggtatcatg agaagagaac cttctaacat aagctgtaat 2800

 tctaaacctg cacttgtccc tctccagcaa gaggctagca ctgaattcat 2850

 tctactcata ctacacaccc agttatggaa tgtccagagt tctcgaagaa 2900

 aataaatgac tttaggaaga ggtatacatt ttttaagtcg ctctgcctcc 2950

 aaatctgaac agtcactgta aatcattctt aagcccagat atgagaactt 3000

 ctgctggaaa gtgggaccct ctgagtgggt ggtcagaaaa tacccatgct 3050

 gatgaaatga cctatgccca aagaacaaat acttaacgtg ggagtggaac 3100

 cacatgagcc tgctcagctc tgcataagta attcaagaaa tgggaggctt 3150

 caccttaaaa acagtgtgca aatggcagct agaggttttg ataggaagta 3200

 tgtttgtttc ttagtgttta caaatattaa gtactcttga tacaaaatat 3250

 acttttaaac ttcataacct ttttataaaa gttgttgcag caaaataata 3300

 gcctcggttc tatgcatata tggattgcta taaaaaatgt caataagatt 3350

 gtacaaggaa aattagagaa agtcacattt agggtttatt ttttacactt 3400

 ggccagtaaa atagggtaaa tcctattaga aattttttaa agaacttttt 3450

 ttaagtttcc taaatctgtg tgtgtattgt gaagtggtat aagaaatgac 3500

 tttgaaccac tttgcaattg tagattccca acaataaaat tgaagat 3547

<210> 5501
<211> 574
<212> PRT
<213> Homo sapien

<400> 5501
 Met Cys Pro Arg Ala Ala Arg Ala Pro Ala Thr Leu Leu Leu Ala
   1               5                  10                  15

 Leu Gly Ala Val Leu Trp Pro Ala Ala Gly Ala Trp Glu Leu Thr
                  20                  25                  30

 Ile Leu His Thr Asn Asp Val His Ser Arg Leu Glu Gln Thr Ser
                  35                  40                  45

 Glu Asp Ser Ser Lys Cys Val Asn Ala Ser Arg Cys Met Gly Gly
                  50                  55                  60

 Val Ala Arg Leu Phe Thr Lys Val Gln Gln Ile Arg Arg Ala Glu
                  65                  70                  75

 Pro Asn Val Leu Leu Leu Asp Ala Gly Asp Gln Tyr Gln Gly Thr
                  80                  85                  90

 Ile Trp Phe Thr Val Tyr Lys Gly Ala Glu Val Ala His Phe Met
                  95                 100                 105

 Asn Ala Leu Arg Tyr Asp Ala Met Ala Leu Gly Asn His Glu Phe
                 110                 115                 120

 Asp Asn Gly Val Glu Gly Leu Ile Glu Pro Leu Leu Lys Glu Ala
                 125                 130                 135

 Lys Phe Pro Ile Leu Ser Ala Asn Ile Lys Ala Lys Gly Pro Leu
                 140                 145                 150

 Ala Ser Gln Ile Ser Gly Leu Tyr Leu Pro Tyr Lys Val Leu Pro
                 155                 160                 165

 Val Gly Asp Glu Val Val Gly Ile Val Gly Tyr Thr Ser Lys Glu
                 170                 175                 180

 Thr Pro Phe Leu Ser Asn Pro Gly Thr Asn Leu Val Phe Glu Asp
                 185                 190                 195

 Glu Ile Thr Ala Leu Gln Pro Glu Val Asp Lys Leu Lys Thr Leu
                 200                 205                 210

 Asn Val Asn Lys Ile Ile Ala Leu Gly His Ser Gly Phe Glu Met
                 215                 220                 225

 Asp Lys Leu Ile Ala Gln Lys Val Arg Gly Val Asp Val Val Val
                 230                 235                 240

 Gly Gly His Ser Asn Thr Phe Leu Tyr Thr Gly Asn Pro Pro Ser
                 245                 250                 255

 Lys Glu Val Pro Ala Gly Lys Tyr Pro Phe Ile Val Thr Ser Asp
                 260                 265                 270

 Asp Gly Arg Lys Val Pro Val Val Gln Ala Tyr Ala Phe Gly Lys
                 275                 280                 285

 Tyr Leu Gly Tyr Leu Lys Ile Glu Phe Asp Glu Arg Gly Asn Val
                 290                 295                 300

 Ile Ser Ser His Gly Asn Pro Ile Leu Leu Asn Ser Ser Ile Pro
                 305                 310                 315

 Glu Asp Pro Ser Ile Lys Ala Asp Ile Asn Lys Trp Arg Ile Lys
                 320                 325                 330

 Leu Asp Asn Tyr Ser Thr Gln Glu Leu Gly Lys Thr Ile Val Tyr
                 335                 340                 345

 Leu Asp Gly Ser Ser Gln Ser Cys Arg Phe Arg Glu Cys Asn Met
                 350                 355                 360

 Gly Asn Leu Ile Cys Asp Ala Met Ile Asn Asn Asn Leu Arg His
                 365                 370                 375

 Thr Asp Glu Met Phe Trp Asn His Val Ser Met Cys Ile Leu Asn
                 380                 385                 390

 Gly Gly Gly Ile Arg Ser Pro Ile Asp Glu Arg Asn Asn Gly Thr
                 395                 400                 405

 Ile Thr Trp Glu Asn Leu Ala Ala Val Leu Pro Phe Gly Gly Thr
                 410                 415                 420

 Phe Asp Leu Val Gln Leu Lys Gly Ser Thr Leu Lys Lys Ala Phe
                 425                 430                 435

 Glu His Ser Val His Arg Tyr Gly Gln Ser Thr Gly Glu Phe Leu
                 440                 445                 450

 Gln Val Gly Gly Ile His Val Val Tyr Asp Leu Ser Arg Lys Pro
                 455                 460                 465

 Gly Asp Arg Val Val Lys Leu Asp Val Leu Cys Thr Lys Cys Arg
                 470                 475                 480

 Val Pro Ser Tyr Asp Pro Leu Lys Met Asp Glu Val Tyr Lys Val
                 485                 490                 495

 Ile Leu Pro Asn Phe Leu Ala Asn Gly Gly Asp Gly Phe Gln Met
                 500                 505                 510

 Ile Lys Asp Glu Leu Leu Arg His Asp Ser Gly Asp Gln Asp Ile
                 515                 520                 525

 Asn Val Val Ser Thr Tyr Ile Ser Lys Met Lys Val Ile Tyr Pro
                 530                 535                 540

 Ala Val Glu Gly Arg Ile Lys Phe Ser Thr Gly Ser His Cys His
                 545                 550                 555

 Gly Ser Phe Ser Leu Ile Phe Leu Ser Leu Trp Ala Val Ile Phe
                 560                 565                 570

 Val Leu Tyr Gln


<210> 5502
<211> 2150
<212> DNA
<213> Homo sapien

<400> 5502
 ggaggaggag gaggaggagg aagaagaggt agcggcaagg tcgcggtctg 50

 aggttccggt gctcgccgcc gcccagctcc cagccgaggc tttctcaacc 100

 gcgtcaataa aaggccgccc cgacccgccc ccgcgccccg cagccctgcc 150

 ggacaccccg ggctgcagct gagcgggcgc agacgggccg aggcgggcgc 200

 cgggcgcgca gggaccgagg gaccgagtgc tccccatgag cgcacgtggg 250

 ccgggcggtc cgcaagcccg gctgagagcg cgccatgggg caggcgggct 300

 gcaaggggct ctgcctgtcg ctgttcgact acaagaccga gaagtatgtc 350

 atcgccaaga acaagaaggt gggcctgctg taccggctgc tgcaggcctc 400

 catcctggcg tacctggtcg tatgggtgtt cctgataaag aagggttacc 450

 aagacgtcga cacctccctg cagagtgctg tcatcaccaa agtcaagggc 500

 gtggccttca ccaacacctc ggatcttggg cagcggatct gggatgtcgc 550

 cgactacgtc attccagccc agaatgaagg cattcctgat ggcgcgtgct 600

 ccaaggacag cgactgccac gctggggaag cggttacagc tggaaacgga 650

 gtgaagaccg gccgctgcct gcggagagag aacttggcca ggggcacctg 700

 tgagatcttt gcctggtgcc cgttggagac aagctccagg ccggaggagc 750

 cattcctgaa ggaggccgaa gacttcacca ttttcataaa gaaccacatc 800

 cgtttcccca aattcaactt ctccaacaat gtgatggacg tcaaggacag 850

 atctttcctg aaatcatgcc actttggccc caagaaccac tactgcccca 900

 tcttccgact gggctccgtg atccgctggg ccgggagcga cttccaggat 950

 atagccctgg agggtggcgt gataggaatt aatattgaat ggaactgtga 1000

 tcttgataaa gctgcctctg agtgccaccc tcactattct tttagccgtc 1050

 tggacaataa actttcaaag tctgtctcct ccgggtacaa cttcagattt 1100

 gccagatatt accgagacgc agccggggtg gagttccgca ccctgatgaa 1150

 agcctacggg atccgctttg acgtgatggt gaacggcaag ggtgctttct 1200

 tctgcgacct ggtactcatc tacctcatca aaaagagaga gttttaccgt 1250

 gacaagaagt acgaggaagt gaggggccta gaagacagtt cccaggaggc 1300

 cgaggacgag gcatcggggc tggggctatc tgagcagctc acatctgggc 1350

 cagggctgct ggggatgccg gagcagcagg agctgcagga gccacccgag 1400

 gcgaagcgtg gaagcagcag tcagaagggg aacggatctg tgtgcccaca 1450

 gctcctggag ccccacagga gcacgtgaat tgcctctgct tacgttcagg 1500

 ccctgtccta aacccagccg tctagcaccc agtgatccca tgcctttggg 1550

 aatcccagga tgctgcccaa cgggaaattt gtacattggg tgctatcaat 1600

 gccacatcac agggaccagc catcacagag caaagtgacc tccacgtctg 1650

 atgctggggt catcaggacg gacccatcat ggctgtcttt ttgccccacc 1700

 ccctgccgtc agttcttcct ttctccgtgg ctggcttccc gcactaggga 1750

 acgggttgta aatggggaac atgacttcct tccggagtcc ttgagcacct 1800

 cagctaagga ccgcagtgcc ctgtagagtt cctagattac ctcactggga 1850

 atagcattgt gcgtgtccgg aaaagggctc catttggttc cagcccactc 1900

 ccctctgcaa gtgccgcagc ttccctcaga gcatactctc cagtggatcc 1950

 aagtactctc tctcctaaag acaccacctt cctgccagct gtttgccctt 2000

 aggccagtac acagaattaa agtgggggag atggcagacg ctttctggga 2050

 cctgcccaag atatgtattc tctgacactc ttatttggtc ataaaacaat 2100

 aaatggtgtc aatttcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2150

<210> 5503
<211> 397
<212> PRT
<213> Homo sapien

<400> 5503
 Met Gly Gln Ala Gly Cys Lys Gly Leu Cys Leu Ser Leu Phe Asp
   1               5                  10                  15

 Tyr Lys Thr Glu Lys Tyr Val Ile Ala Lys Asn Lys Lys Val Gly
                  20                  25                  30

 Leu Leu Tyr Arg Leu Leu Gln Ala Ser Ile Leu Ala Tyr Leu Val
                  35                  40                  45

 Val Trp Val Phe Leu Ile Lys Lys Gly Tyr Gln Asp Val Asp Thr
                  50                  55                  60

 Ser Leu Gln Ser Ala Val Ile Thr Lys Val Lys Gly Val Ala Phe
                  65                  70                  75

 Thr Asn Thr Ser Asp Leu Gly Gln Arg Ile Trp Asp Val Ala Asp
                  80                  85                  90

 Tyr Val Ile Pro Ala Gln Asn Glu Gly Ile Pro Asp Gly Ala Cys
                  95                 100                 105

 Ser Lys Asp Ser Asp Cys His Ala Gly Glu Ala Val Thr Ala Gly
                 110                 115                 120

 Asn Gly Val Lys Thr Gly Arg Cys Leu Arg Arg Glu Asn Leu Ala
                 125                 130                 135

 Arg Gly Thr Cys Glu Ile Phe Ala Trp Cys Pro Leu Glu Thr Ser
                 140                 145                 150

 Ser Arg Pro Glu Glu Pro Phe Leu Lys Glu Ala Glu Asp Phe Thr
                 155                 160                 165

 Ile Phe Ile Lys Asn His Ile Arg Phe Pro Lys Phe Asn Phe Ser
                 170                 175                 180

 Asn Asn Val Met Asp Val Lys Asp Arg Ser Phe Leu Lys Ser Cys
                 185                 190                 195

 His Phe Gly Pro Lys Asn His Tyr Cys Pro Ile Phe Arg Leu Gly
                 200                 205                 210

 Ser Val Ile Arg Trp Ala Gly Ser Asp Phe Gln Asp Ile Ala Leu
                 215                 220                 225

 Glu Gly Gly Val Ile Gly Ile Asn Ile Glu Trp Asn Cys Asp Leu
                 230                 235                 240

 Asp Lys Ala Ala Ser Glu Cys His Pro His Tyr Ser Phe Ser Arg
                 245                 250                 255

 Leu Asp Asn Lys Leu Ser Lys Ser Val Ser Ser Gly Tyr Asn Phe
                 260                 265                 270

 Arg Phe Ala Arg Tyr Tyr Arg Asp Ala Ala Gly Val Glu Phe Arg
                 275                 280                 285

 Thr Leu Met Lys Ala Tyr Gly Ile Arg Phe Asp Val Met Val Asn
                 290                 295                 300

 Gly Lys Gly Ala Phe Phe Cys Asp Leu Val Leu Ile Tyr Leu Ile
                 305                 310                 315

 Lys Lys Arg Glu Phe Tyr Arg Asp Lys Lys Tyr Glu Glu Val Arg
                 320                 325                 330

 Gly Leu Glu Asp Ser Ser Gln Glu Ala Glu Asp Glu Ala Ser Gly
                 335                 340                 345

 Leu Gly Leu Ser Glu Gln Leu Thr Ser Gly Pro Gly Leu Leu Gly
                 350                 355                 360

 Met Pro Glu Gln Gln Glu Leu Gln Glu Pro Pro Glu Ala Lys Arg
                 365                 370                 375

 Gly Ser Ser Ser Gln Lys Gly Asn Gly Ser Val Cys Pro Gln Leu
                 380                 385                 390

 Leu Glu Pro His Arg Ser Thr
                 395

<210> 5504
<211> 4180
<212> DNA
<213> Homo sapien

<400> 5504
 gcggggaagc agcagcggcc aggatgaatc ccaggtgctc tggagctgga 50

 tggtgaaggt cggcactctt caccctcccg agccctgccc gtctcggccc 100

 catgccccca ccagtcagcc ccgggccaca ggcagtgagc aggcacctgg 150

 gagccgaggc cctgtgacca ggccaaggag acgggcgctc cagggtccca 200

 gccacctgtc ccccccatgg agctgaggcc ctggttgcta tgggtggtag 250

 cagcaacagg aaccttggtc ctgctagcag ctgatgctca gggccagaag 300

 gtcttcacca acacgtgggc tgtgcgcatc cctggaggcc cagcggtggc 350

 caacagtgtg gcacggaagc atgggttcct caacctgggc cagatcttcg 400

 gggactatta ccacttctgg catcgaggag tgacgaagcg gtccctgtcg 450

 cctcaccgcc cgcggcacag ccggctgcag agggagcctc aagtacagtg 500

 gctggaacag caggtggcaa agcgacggac taaacgggac gtgtaccagg 550

 agcccacaga ccccaagttt cctcagcagt ggtacctgtc tggtgtcact 600

 cagcgggacc tgaatgtgaa ggcggcctgg gcgcagggct acacagggca 650

 cggcattgtg gtctccattc tggacgatgg catcgagaag aaccacccgg 700

 acttggcagg caattatgat cctggggcca gttttgatgt caatgaccag 750

 gaccctgacc cccagcctcg gtacacacag atgaatgaca acaggcacgg 800

 cacacggtgt gcgggggaag tggctgcggt ggccaacaac ggtgtctgtg 850

 gtgtaggtgt ggcctacaac gcccgcattg gaggggtgcg catgctggat 900

 ggcgaggtga cagatgcagt ggaggcacgc tcgctgggcc tgaaccccaa 950

 ccacatccac atctacagtg ccagctgggg ccccgaggat gacggcaaga 1000

 cagtggatgg gccagcccgc ctcgccgagg aggccttctt ccgtggggtt 1050

 agccagggcc gaggggggct gggctccatc tttgtctggg cctcggggaa 1100

 cgggggccgg gaacatgaca gctgcaactg cgacggctac accaacagta 1150

 tctacacgct gtccatcagc agcgccacgc agtttggcaa cgtgccgtgg 1200

 tacagcgagg cctgctcgtc cacactggcc acgacctaca gcagtggcaa 1250

 ccagaatgag aagcagatcg tgacgactga cttgcggcag aagtgcacgg 1300

 agtctcacac gggcacctca gcctctgccc ccttagcagc cggcatcatt 1350

 gctctcaccc tggaggccaa taagaacctc acatggcggg acatgcaaca 1400

 cctggtggta cagacctcga agccagccca cctcaatgcc aacgactggg 1450

 ccaccaatgg tgtgggccgg aaagtgagcc actcatatgg ctacgggctt 1500

 ttggacgcag gcgccatggt ggccctggcc cagaattgga ccacagtggc 1550

 cccccagcgg aagtgcatca tcgacatcct caccgagccc aaagacatcg 1600

 ggaaacggct cgaggtgcgg aagaccgtga ccgcgtgcct gggcgagccc 1650

 aaccacatca ctcggctgga gcacgctcag gcgcggctca ccctgtccta 1700

 taatcgccgt ggcgacctgg ccatccacct ggtcagcccc atgggcaccc 1750

 gctccaccct gctggcagcc aggccacatg actactccgc agatgggttt 1800

 aatgactggg ccttcatgac aactcattcc tgggatgagg atccctctgg 1850

 cgagtgggtc ctagagattg aaaacaccag cgaagccaac aactatggga 1900

 cgctgaccaa gttcaccctc gtactctatg gcaccgcccc tgaggggctg 1950

 cccgtacctc cagaaagcag tggctgcaag accctcacgt ccagtcaggc 2000

 ctgtgtggtg tgcgaggaag gcttctccct gcaccagaag agctgtgtcc 2050

 agcactgccc tccagggttc gccccccaag tcctcgatac gcactatagc 2100

 accgagaatg acgtggagac catccgggcc agcgtctgcg ccccctgcca 2150

 cgcctcatgt gccacatgcc aggggccggc cctgacagac tgcctcagct 2200

 gccccagcca cgcctccttg gaccctgtgg agcagacttg ctcccggcaa 2250

 agccagagca gccgagagtc cccgccacag cagcagccac ctcggctgcc 2300

 cccggaggtg gaggcggggc aacggctgcg ggcagggctg ctgccctcac 2350

 acctgcctga ggtggtggcc ggcctcagct gcgccttcat cgtgctggtc 2400

 ttcgtcactg tcttcctggt cctgcagctg cgctctggct ttagttttcg 2450

 gggggtgaag gtgtacacca tggaccgtgg cctcatctcc tacaaggggc 2500

 tgccccctga agcctggcag gaggagtgcc cgtctgactc agaagaggac 2550

 gagggccggg gcgagaggac cgcctttatc aaagaccaga gcgccctctg 2600

 atgagcccac tgcccacccc ctcaagccaa tcccctcctt gggcactttt 2650

 taattcacca aagtattttt ttatcttggg actgggtttg gaccccagct 2700

 gggaggcaag aggggtggag actgcttccc atcctaccct cgggcccacc 2750

 tggccacctg aggtgggccc aggaccagct ggggcgtggg gagggccgta 2800

 ccccaccctc agcacccctt ccatgtggag aaaggagtga aacctttagg 2850

 gcagcttgcc ccggccccgg ccccagccag agttcctgcg gagtgaagag 2900

 gggcagccct tgcttgttgg gattcctgac ccaggccgca gctcttgccc 2950

 ttccctgtcc ctctaaagca ataatggtcc catccaggca gtcgggggct 3000

 ggcctaggag atatctgagg gaggaggcca cctctccaag ggcttctgca 3050

 ccctccaccc tgtcccccag ctctggtgag tcttggcggc agcagccatc 3100

 ataggaaggg accaaggcaa ggcaggtgcc tccaggtgtg cacgtggcat 3150

 gtggcctgtg gcctgtgtcc catgacccac ccctgtgctc cgtgcctcca 3200

 ccaccactgg ccaccaggct ggcgcagcca aggccgaagc tctggctgaa 3250

 ccctgtgctg gtgtcctgac caccctcccc tctcttgcac ccgcctctcc 3300

 cgtcagggcc caagtccctg ttttctgagc ccgggctgcc tgggctgttg 3350

 gcactcacag acctggagcc cctgggtggg tggtggggag gggcgctggc 3400

 ccagccggcc tctctggcct cccacccgat gctgctttcc cctgtgggga 3450

 tctcaggggc tgtttgagga tatattttca ctttgtgatt atttcacttt 3500

 agatgctgat gatttgtttt tgtattttta atgggggtag cagctggact 3550

 acccacgttc tcacacccac cgtccgccct gctcctccct ggctgccctg 3600

 gccctgaggt gtgggggctg cagcatgttg ctgaggagtg aggaatagtt 3650

 gagccccaag tcctgaagag gcgggccagc caggcgggct caaggaaagg 3700

 gggtcccagt gggaggggca ggctgacatc tgtgtttcaa gtggggctcg 3750

 ccatgccggg ggttcatagg tcactggctc tccaagtgcc agaggtgggc 3800

 aggtggtggc actgagcccc cccaacactg tgccctggtg gagaaagcac 3850

 tgacctgtca tgcccccctc aaacctcctc ttctgacgtg ccttttgcac 3900

 ccctcccatt aggacaatca gtcccctccc atctgggagt ccccttttct 3950

 tttctaccct agccattcct ggtacccagc catctgccca ggggtgcccc 4000

 ctcctctccc atccccctgc cctcgtggcc agcccggctg gttttgtaag 4050

 atgctgggtt ggtgcacagt gatttttttc ttgtaattta aacaggccca 4100

 gcattgctgg ttctatttaa tggacatgag ataatgttag aggttttaaa 4150

 gtgattaaac gtgcagacta tgcaaaccag 4180

<210> 5505
<211> 794
<212> PRT
<213> Homo sapien

<400> 5505
 Met Glu Leu Arg Pro Trp Leu Leu Trp Val Val Ala Ala Thr Gly
   1               5                  10                  15

 Thr Leu Val Leu Leu Ala Ala Asp Ala Gln Gly Gln Lys Val Phe
                  20                  25                  30

 Thr Asn Thr Trp Ala Val Arg Ile Pro Gly Gly Pro Ala Val Ala
                  35                  40                  45

 Asn Ser Val Ala Arg Lys His Gly Phe Leu Asn Leu Gly Gln Ile
                  50                  55                  60

 Phe Gly Asp Tyr Tyr His Phe Trp His Arg Gly Val Thr Lys Arg
                  65                  70                  75

 Ser Leu Ser Pro His Arg Pro Arg His Ser Arg Leu Gln Arg Glu
                  80                  85                  90

 Pro Gln Val Gln Trp Leu Glu Gln Gln Val Ala Lys Arg Arg Thr
                  95                 100                 105

 Lys Arg Asp Val Tyr Gln Glu Pro Thr Asp Pro Lys Phe Pro Gln
                 110                 115                 120

 Gln Trp Tyr Leu Ser Gly Val Thr Gln Arg Asp Leu Asn Val Lys
                 125                 130                 135

 Ala Ala Trp Ala Gln Gly Tyr Thr Gly His Gly Ile Val Val Ser
                 140                 145                 150

 Ile Leu Asp Asp Gly Ile Glu Lys Asn His Pro Asp Leu Ala Gly
                 155                 160                 165

 Asn Tyr Asp Pro Gly Ala Ser Phe Asp Val Asn Asp Gln Asp Pro
                 170                 175                 180

 Asp Pro Gln Pro Arg Tyr Thr Gln Met Asn Asp Asn Arg His Gly
                 185                 190                 195

 Thr Arg Cys Ala Gly Glu Val Ala Ala Val Ala Asn Asn Gly Val
                 200                 205                 210

 Cys Gly Val Gly Val Ala Tyr Asn Ala Arg Ile Gly Gly Val Arg
                 215                 220                 225

 Met Leu Asp Gly Glu Val Thr Asp Ala Val Glu Ala Arg Ser Leu
                 230                 235                 240

 Gly Leu Asn Pro Asn His Ile His Ile Tyr Ser Ala Ser Trp Gly
                 245                 250                 255

 Pro Glu Asp Asp Gly Lys Thr Val Asp Gly Pro Ala Arg Leu Ala
                 260                 265                 270

 Glu Glu Ala Phe Phe Arg Gly Val Ser Gln Gly Arg Gly Gly Leu
                 275                 280                 285

 Gly Ser Ile Phe Val Trp Ala Ser Gly Asn Gly Gly Arg Glu His
                 290                 295                 300

 Asp Ser Cys Asn Cys Asp Gly Tyr Thr Asn Ser Ile Tyr Thr Leu
                 305                 310                 315

 Ser Ile Ser Ser Ala Thr Gln Phe Gly Asn Val Pro Trp Tyr Ser
                 320                 325                 330

 Glu Ala Cys Ser Ser Thr Leu Ala Thr Thr Tyr Ser Ser Gly Asn
                 335                 340                 345

 Gln Asn Glu Lys Gln Ile Val Thr Thr Asp Leu Arg Gln Lys Cys
                 350                 355                 360

 Thr Glu Ser His Thr Gly Thr Ser Ala Ser Ala Pro Leu Ala Ala
                 365                 370                 375

 Gly Ile Ile Ala Leu Thr Leu Glu Ala Asn Lys Asn Leu Thr Trp
                 380                 385                 390

 Arg Asp Met Gln His Leu Val Val Gln Thr Ser Lys Pro Ala His
                 395                 400                 405

 Leu Asn Ala Asn Asp Trp Ala Thr Asn Gly Val Gly Arg Lys Val
                 410                 415                 420

 Ser His Ser Tyr Gly Tyr Gly Leu Leu Asp Ala Gly Ala Met Val
                 425                 430                 435

 Ala Leu Ala Gln Asn Trp Thr Thr Val Ala Pro Gln Arg Lys Cys
                 440                 445                 450

 Ile Ile Asp Ile Leu Thr Glu Pro Lys Asp Ile Gly Lys Arg Leu
                 455                 460                 465

 Glu Val Arg Lys Thr Val Thr Ala Cys Leu Gly Glu Pro Asn His
                 470                 475                 480

 Ile Thr Arg Leu Glu His Ala Gln Ala Arg Leu Thr Leu Ser Tyr
                 485                 490                 495

 Asn Arg Arg Gly Asp Leu Ala Ile His Leu Val Ser Pro Met Gly
                 500                 505                 510

 Thr Arg Ser Thr Leu Leu Ala Ala Arg Pro His Asp Tyr Ser Ala
                 515                 520                 525

 Asp Gly Phe Asn Asp Trp Ala Phe Met Thr Thr His Ser Trp Asp
                 530                 535                 540

 Glu Asp Pro Ser Gly Glu Trp Val Leu Glu Ile Glu Asn Thr Ser
                 545                 550                 555

 Glu Ala Asn Asn Tyr Gly Thr Leu Thr Lys Phe Thr Leu Val Leu
                 560                 565                 570

 Tyr Gly Thr Ala Pro Glu Gly Leu Pro Val Pro Pro Glu Ser Ser
                 575                 580                 585

 Gly Cys Lys Thr Leu Thr Ser Ser Gln Ala Cys Val Val Cys Glu
                 590                 595                 600

 Glu Gly Phe Ser Leu His Gln Lys Ser Cys Val Gln His Cys Pro
                 605                 610                 615

 Pro Gly Phe Ala Pro Gln Val Leu Asp Thr His Tyr Ser Thr Glu
                 620                 625                 630

 Asn Asp Val Glu Thr Ile Arg Ala Ser Val Cys Ala Pro Cys His
                 635                 640                 645

 Ala Ser Cys Ala Thr Cys Gln Gly Pro Ala Leu Thr Asp Cys Leu
                 650                 655                 660

 Ser Cys Pro Ser His Ala Ser Leu Asp Pro Val Glu Gln Thr Cys
                 665                 670                 675

 Ser Arg Gln Ser Gln Ser Ser Arg Glu Ser Pro Pro Gln Gln Gln
                 680                 685                 690

 Pro Pro Arg Leu Pro Pro Glu Val Glu Ala Gly Gln Arg Leu Arg
                 695                 700                 705

 Ala Gly Leu Leu Pro Ser His Leu Pro Glu Val Val Ala Gly Leu
                 710                 715                 720

 Ser Cys Ala Phe Ile Val Leu Val Phe Val Thr Val Phe Leu Val
                 725                 730                 735

 Leu Gln Leu Arg Ser Gly Phe Ser Phe Arg Gly Val Lys Val Tyr
                 740                 745                 750

 Thr Met Asp Arg Gly Leu Ile Ser Tyr Lys Gly Leu Pro Pro Glu
                 755                 760                 765

 Ala Trp Gln Glu Glu Cys Pro Ser Asp Ser Glu Glu Asp Glu Gly
                 770                 775                 780

 Arg Gly Glu Arg Thr Ala Phe Ile Lys Asp Gln Ser Ala Leu
                 785                 790

<210> 5506
<211> 741
<212> DNA
<213> Homo sapien

<400> 5506
 gagaaatttt tcattttctt tcttgtttga ctgtatgcaa acatcaaact 50

 aagaatggca aagatgaatc tctcttccta tatattaata ctaacttttt 100

 ctttgttttc tcaaggtatt ttactttcag catccaagtc cataagaaat 150

 ttagatgatg acatggtatt taatacattc aggttgggga aaggctttca 200

 gaaggaagac actgcagaaa aatcagttat tgctccttcc ctggaacaat 250

 ataaaaatga tgagagcagt ttcatgaacg aagaggaaaa taaagtttca 300

 aagaacacag gctccaaaca taatttctta aatcatggtc tgccactcaa 350

 tctggctata aaaggatatc aagcactaaa aggatctgta gatttcccag 400

 ctgagaatgg agttcagaat actgaatcaa cacaagaaaa gagagaaatt 450

 ggggatgaag aaaactcagc taaatttcct ataggaagga gagattttga 500

 catgctcaga tgtatgctcg gaagagtcta ccgaccctgt tggcaagtct 550

 gatacctgtt ggtccacatc atcttttcag aagaaaataa aagcatttaa 600

 ttgccaatgg gaggagaagc ccatactgct actataactt gtgtatgtta 650

 aatgtctgtt ttaaaagaaa gtagtgttaa atgtatcagt aactgaaatg 700

 atatgctttc tctgtgcatt aaatttgtga aaattctgca t 741

<210> 5507
<211> 165
<212> PRT
<213> Homo sapien

<400> 5507
 Met Ala Lys Met Asn Leu Ser Ser Tyr Ile Leu Ile Leu Thr Phe
   1               5                  10                  15

 Ser Leu Phe Ser Gln Gly Ile Leu Leu Ser Ala Ser Lys Ser Ile
                  20                  25                  30

 Arg Asn Leu Asp Asp Asp Met Val Phe Asn Thr Phe Arg Leu Gly
                  35                  40                  45

 Lys Gly Phe Gln Lys Glu Asp Thr Ala Glu Lys Ser Val Ile Ala
                  50                  55                  60

 Pro Ser Leu Glu Gln Tyr Lys Asn Asp Glu Ser Ser Phe Met Asn
                  65                  70                  75

 Glu Glu Glu Asn Lys Val Ser Lys Asn Thr Gly Ser Lys His Asn
                  80                  85                  90

 Phe Leu Asn His Gly Leu Pro Leu Asn Leu Ala Ile Lys Gly Tyr
                  95                 100                 105

 Gln Ala Leu Lys Gly Ser Val Asp Phe Pro Ala Glu Asn Gly Val
                 110                 115                 120

 Gln Asn Thr Glu Ser Thr Gln Glu Lys Arg Glu Ile Gly Asp Glu
                 125                 130                 135

 Glu Asn Ser Ala Lys Phe Pro Ile Gly Arg Arg Asp Phe Asp Met
                 140                 145                 150

 Leu Arg Cys Met Leu Gly Arg Val Tyr Arg Pro Cys Trp Gln Val
                 155                 160                 165

<210> 5508
<211> 2165
<212> DNA
<213> Homo sapien

<400> 5508
 gtcccgttac cgcctcctgc tcctgccgcg cgcacccccg gggcttcggc 50

 tccggcacgg gtcgcgccca gctttcctgc acctgaggcc gccggccagc 100

 cgccgccatg ggtgcctacc tctcccagcc caacacggtg aagtgctccg 150

 gggacggggt cggcgccccg cgcctgccgc tgccctacgg cttctccgcc 200

 atgcaaggct ggcgcgtctc catggaggat gctcacaact gtattcctga 250

 gctggacagt gagacagcca tgttttctgt ctacgatgga catggagggg 300

 aggaagttgc cttgtactgt gccaaatatc ttcctgatat catcaaagat 350

 cagaaggcct acaaggaagg caagctacag aaggctttag aagatgcctt 400

 cttggctatt gacgccaaat tgaccactga agaagtcatt aaagagctgg 450

 cacagattgc agggcgaccc actgaggatg aagatgaaaa agaaaaagta 500

 gctgatgaag atgatgtgga caatgaggag gctgcactgc tgcatgaaga 550

 ggctaccatg actattgaag agctgctgac acgctacggg cagaactgtc 600

 acaagggccc tccccacagc aaatctggag gtgggacagg cgaggaacca 650

 gggtcccagg gcctcaatgg ggaggcagga cctgaggact caactaggga 700

 aactccttca caagaaaatg gccccacagc caaggcctac acaggctttt 750

 cctccaactc ggaacgtggg actgaggcag gccaagttgg tgagcctggc 800

 attcccactg gtgaggctgg gccttcctgc tcttcagcct ctgacaagct 850

 gcctcgagtt gctaagtcca agttctttga ggacagtgag gatgagtcag 900

 atgaggcgga ggaagaagag gaagacagtg aggaatgcag cgaggaagag 950

 gatggctaca gcagtgagga ggcagagaat gaggaagatg aggatgacac 1000

 cgaggaggct gaagaggacg atgaagaaga agaagaagag atgatggtgc 1050

 cagggatgga aggcaaagag gagcctggct ctgacagtgg tacaacagcg 1100

 gtggtggccc tgatacgagg gaagcagttg attgtagcca acgcaggaga 1150

 ctctcgctgt gtggtatctg aggctggcaa agctttagac atgtcctatg 1200

 atcacaaacc agaggatgaa gtagaactag cacgcatcaa gaatgctggt 1250

 ggcaaggtca ccatggatgg gcgagtcaac gggggcctca acctctccag 1300

 agccattggg gaccacttct ataagagaaa caagaacctg ccacctgagg 1350

 aacagatgat ttcagccctt cctgacatca aggtgctgac tctcactgac 1400

 gaccatgaat tcatggtcat tgcctgtgat ggcatctgga atgtgatgag 1450

 cagccaggaa gttgtagatt tcattcaatc aaagatcagc cagcgtgatg 1500

 aaaatgggga gcttcggtta ttgtcatcca ttgtggaaga gctgctggat 1550

 cagtgcctgg caccagacac ttctggggat ggtacagggt gtgacaacat 1600

 gacctgcatc atcatttgct tcaagccccg aaacacagca gagctccagc 1650

 cagagagtgg caagcgaaaa ctagaggagg tgctctctac tgagggggct 1700

 gaagaaaatg gcaacagcga caagaagaag aaggccaagc gagactagca 1750

 gtcatccaga cccctgccca cctagactgt tttctgagcc ctccggacct 1800

 gagactgagt tttgtctttt tcctttagcc ttagcagtgg gtatgaggtg 1850

 tgcaggggga gctgggtggc ttcactccgc ccattccaaa gagggctctc 1900

 cctccacact gcagccggga gcctctgctg tccttcccag ccgcctctgc 1950

 tcctcgggct catcaccggt tctgtgcctg tgctctgttg tgttggaggg 2000

 aaggactggc ggttctggtt tttactctgt gaactttatt taaggacatt 2050

 cttttttatt ggcggctcca tggccctcgg ccgcttgcac ccgctctctg 2100

 ttgtacactt tcaatcaaca ctttttcaga ctaaaggcca aaacctaatc 2150

 gtaaaaaaaa aaaaa 2165

<210> 5509
<211> 2808
<212> DNA
<213> Homo sapien

<400> 5509
 gcggcggcgg cggcgcagtt tgctcatact ttgtgacttg cggtcacagt 50

 ggcattcagc tccacacttg gtagaaccac aggcacgaca agcatagaaa 100

 catcctaaac aatcttcatc gaggcatcga ggtccatccc aataaaaatc 150

 aggagaccct ggctatcata gaccttagtc ttcgctggta tactcgctgt 200

 ctgtcaacca gcggttgact ttttttaagc cttctttttt ctcttttacc 250

 agtttctgga gcaaattcag tttgccttcc tggatttgta aattgtaatg 300

 acctcaaaac tttagcagtt cttccatctg actcaggttt gcttctctgg 350

 cggtcttcag aatcaacatc cacacttccg tgattatctg cgtgcatttt 400

 ggacaaagct tccaaccagg atacgggaag aagaaatggc tggtgatctt 450

 tcagcaggtt tcttcatgga ggaacttaat acataccgtc agaagcaggg 500

 agtagtactt aaatatcaag aactgcctaa ttcaggacct ccacatgata 550

 ggaggtttac atttcaagtt ataatagatg gaagagaatt tccagaaggt 600

 gaaggtagat caaagaagga agcaaaaaat gccgcagcca aattagctgt 650

 tgagatactt aataaggaaa agaaggcagt tagtccttta ttattgacaa 700

 caacgaattc ttcagaagga ttatccatgg ggaattacat aggccttatc 750

 aatagaattg cccagaagaa aagactaact gtaaattatg aacagtgtgc 800

 atcgggggtg catgggccag aaggatttca ttataaatgc aaaatgggac 850

 agaaagaata tagtattggt acaggttcta ctaaacagga agcaaaacaa 900

 ttggccgcta aacttgcata tcttcagata ttatcagaag aaacctcagt 950

 gaaatctgac tacctgtcct ctggttcttt tgctactacg tgtgagtccc 1000

 aaagcaactc tttagtgacc agcacactcg cttctgaatc atcatctgaa 1050

 ggtgacttct cagcagatac atcagagata aattctaaca gtgacagttt 1100

 aaacagttct tcgttgctta tgaatggtct cagaaataat caaaggaagg 1150

 caaaaagatc tttggcaccc agatttgacc ttcctgacat gaaagaaaca 1200

 aagtatactg tggacaagag gtttggcatg gattttaaag aaatagaatt 1250

 aattggctca ggtggatttg gccaagtttt caaagcaaaa cacagaattg 1300

 acggaaagac ttacgttatt aaacgtgtta aatataataa cgagaaggcg 1350

 gagcgtgaag taaaagcatt ggcaaaactt gatcatgtaa atattgttca 1400

 ctacaatggc tgttgggatg gatttgatta tgatcctgag accagtgatg 1450

 attctcttga gagcagtgat tatgatcctg agaacagcaa aaatagttca 1500

 aggtcaaaga ctaagtgcct tttcatccaa atggaattct gtgataaagg 1550

 gaccttggaa caatggattg aaaaaagaag aggcgagaaa ctagacaaag 1600

 ttttggcttt ggaactcttt gaacaaataa caaaaggggt ggattatata 1650

 cattcaaaaa aattaattca tagagatctt aagccaagta atatattctt 1700

 agtagataca aaacaagtaa agattggaga ctttggactt gtaacatctc 1750

 tgaaaaatga tggaaagcga acaaggagta agggaacttt gcgatacatg 1800

 agcccagaac agatttcttc gcaagactat ggaaaggaag tggacctcta 1850

 cgctttgggg ctaattcttg ctgaacttct tcatgtatgt gacactgctt 1900

 ttgaaacatc aaagtttttc acagacctac gggatggcat catctcagat 1950

 atatttgata aaaaagaaaa aactcttcta cagaaattac tctcaaagaa 2000

 acctgaggat cgacctaaca catctgaaat actaaggacc ttgactgtgt 2050

 ggaagaaaag cccagagaaa aatgaacgac acacatgtta gagcccttct 2100

 gaaaaagtat cctgcttctg atatgcagtt ttccttaaat tatctaaaat 2150

 ctgctaggga atatcaatag atatttacct tttattttaa tgtttccttt 2200

 aattttttac tatttttact aatctttctg cagaaacaga aaggttttct 2250

 tctttttgct tcaaaaacat tcttacattt tactttttcc tggctcatct 2300

 ctttattctt tttttttttt ttaaagacag agtctcgctc tgttgcccag 2350

 gctggagtgc aatgacacag tcttggctca ctgcaacttc tgcctcttgg 2400

 gttcaagtga ttctcctgcc tcagcctcct gagtagctgg attacaggca 2450

 tgtgccaccc acccaactaa tttttgtgtt tttaataaag acagggtttc 2500

 accatgttgg ccaggctggt ctcaaactcc tgacctcaag taatccacct 2550

 gcctcggcct cccaaagtgc tgggattaca gggatgagcc accgcgccca 2600

 gcctcatctc tttgttctaa agatggaaaa accaccccca aattttcttt 2650

 ttatactatt aatgaatcaa tcaattcata tctatttatt aaatttctac 2700

 cgcttttagg ccaaaaaaat gtaagatcgt tctctgcctc acatagctta 2750

 caagccagct ggagaaatat ggtactcatt aaaaaaaaaa aaaaagtgat 2800

 gtacaacc 2808

<210> 5510
<211> 551
<212> PRT
<213> Homo sapien

<400> 5510
 Met Ala Gly Asp Leu Ser Ala Gly Phe Phe Met Glu Glu Leu Asn
   1               5                  10                  15

 Thr Tyr Arg Gln Lys Gln Gly Val Val Leu Lys Tyr Gln Glu Leu
                  20                  25                  30

 Pro Asn Ser Gly Pro Pro His Asp Arg Arg Phe Thr Phe Gln Val
                  35                  40                  45

 Ile Ile Asp Gly Arg Glu Phe Pro Glu Gly Glu Gly Arg Ser Lys
                  50                  55                  60

 Lys Glu Ala Lys Asn Ala Ala Ala Lys Leu Ala Val Glu Ile Leu
                  65                  70                  75

 Asn Lys Glu Lys Lys Ala Val Ser Pro Leu Leu Leu Thr Thr Thr
                  80                  85                  90

 Asn Ser Ser Glu Gly Leu Ser Met Gly Asn Tyr Ile Gly Leu Ile
                  95                 100                 105

 Asn Arg Ile Ala Gln Lys Lys Arg Leu Thr Val Asn Tyr Glu Gln
                 110                 115                 120

 Cys Ala Ser Gly Val His Gly Pro Glu Gly Phe His Tyr Lys Cys
                 125                 130                 135

 Lys Met Gly Gln Lys Glu Tyr Ser Ile Gly Thr Gly Ser Thr Lys
                 140                 145                 150

 Gln Glu Ala Lys Gln Leu Ala Ala Lys Leu Ala Tyr Leu Gln Ile
                 155                 160                 165

 Leu Ser Glu Glu Thr Ser Val Lys Ser Asp Tyr Leu Ser Ser Gly
                 170                 175                 180

 Ser Phe Ala Thr Thr Cys Glu Ser Gln Ser Asn Ser Leu Val Thr
                 185                 190                 195

 Ser Thr Leu Ala Ser Glu Ser Ser Ser Glu Gly Asp Phe Ser Ala
                 200                 205                 210

 Asp Thr Ser Glu Ile Asn Ser Asn Ser Asp Ser Leu Asn Ser Ser
                 215                 220                 225

 Ser Leu Leu Met Asn Gly Leu Arg Asn Asn Gln Arg Lys Ala Lys
                 230                 235                 240

 Arg Ser Leu Ala Pro Arg Phe Asp Leu Pro Asp Met Lys Glu Thr
                 245                 250                 255

 Lys Tyr Thr Val Asp Lys Arg Phe Gly Met Asp Phe Lys Glu Ile
                 260                 265                 270

 Glu Leu Ile Gly Ser Gly Gly Phe Gly Gln Val Phe Lys Ala Lys
                 275                 280                 285

 His Arg Ile Asp Gly Lys Thr Tyr Val Ile Lys Arg Val Lys Tyr
                 290                 295                 300

 Asn Asn Glu Lys Ala Glu Arg Glu Val Lys Ala Leu Ala Lys Leu
                 305                 310                 315

 Asp His Val Asn Ile Val His Tyr Asn Gly Cys Trp Asp Gly Phe
                 320                 325                 330

 Asp Tyr Asp Pro Glu Thr Ser Asp Asp Ser Leu Glu Ser Ser Asp
                 335                 340                 345

 Tyr Asp Pro Glu Asn Ser Lys Asn Ser Ser Arg Ser Lys Thr Lys
                 350                 355                 360

 Cys Leu Phe Ile Gln Met Glu Phe Cys Asp Lys Gly Thr Leu Glu
                 365                 370                 375

 Gln Trp Ile Glu Lys Arg Arg Gly Glu Lys Leu Asp Lys Val Leu
                 380                 385                 390

 Ala Leu Glu Leu Phe Glu Gln Ile Thr Lys Gly Val Asp Tyr Ile
                 395                 400                 405

 His Ser Lys Lys Leu Ile His Arg Asp Leu Lys Pro Ser Asn Ile
                 410                 415                 420

 Phe Leu Val Asp Thr Lys Gln Val Lys Ile Gly Asp Phe Gly Leu
                 425                 430                 435

 Val Thr Ser Leu Lys Asn Asp Gly Lys Arg Thr Arg Ser Lys Gly
                 440                 445                 450

 Thr Leu Arg Tyr Met Ser Pro Glu Gln Ile Ser Ser Gln Asp Tyr
                 455                 460                 465

 Gly Lys Glu Val Asp Leu Tyr Ala Leu Gly Leu Ile Leu Ala Glu
                 470                 475                 480

 Leu Leu His Val Cys Asp Thr Ala Phe Glu Thr Ser Lys Phe Phe
                 485                 490                 495

 Thr Asp Leu Arg Asp Gly Ile Ile Ser Asp Ile Phe Asp Lys Lys
                 500                 505                 510

 Glu Lys Thr Leu Leu Gln Lys Leu Leu Ser Lys Lys Pro Glu Asp
                 515                 520                 525

 Arg Pro Asn Thr Ser Glu Ile Leu Arg Thr Leu Thr Val Trp Lys
                 530                 535                 540

 Lys Ser Pro Glu Lys Asn Glu Arg His Thr Cys
                 545                 550

<210> 5511
<211> 1583
<212> DNA
<213> Homo sapien

<400> 5511
 gattcgctgc tccgcagcac ggccggagct ggtcgggtca agagtcggga 50

 tttgtgggga gaggttttcc actggtcaag agaaggcttt aagaaagacg 100

 gtattaatct cccgttgcgg ctcccgcctg gtcccatctt ctgcccgctc 150

 ctccaggaaa tgaatctgct gccgaatatt gagagtccag tgactcggca 200

 ggagaagatg gcgaccgtgt gggatgaggc cgagcaagat ggaattgggg 250

 aggaggtgct caagatgtcc acggaggaga tcatccagcg cacacggctg 300

 ctggacagtg agatcaagat catgaagagt gaagtgttga gagtcaccca 350

 tgagctccaa gccatgaagg acaagataaa agagaacagt gagaaaatca 400

 aagtgaacaa gaccctgccg taccttgtct ccaacgtcat cgagctcctg 450

 gatgttgatc ctaatgacca agaggaggat ggtgccaata ttgacctgga 500

 ctcccagagg aagggcaagt gtgctgtgat caaaacctct acacgacaga 550

 cgtacttcct tcctgtgatt gggttggtgg atgctgaaaa gctaaagcca 600

 ggagacctgg tgggtgtgaa caaagactcc tatctgatcc tggagacgct 650

 gcccacagag tatgactcgc gggtgaaggc catggaggta gacgagaggc 700

 ccacggagca atacagtgac attgggggtt tggacaagca gatccaggag 750

 ctggtggagg ccattgtctt gccaatgaac cacaaggaga agtttgagaa 800

 cttggggatc caacctccaa aaggggtgct gatgtatggg cccccaggga 850

 cggggaagac cctcctggcc cgggcctgtg ccgcacagac taaggccacc 900

 ttcctaaagc tggctggccc ccagctggtg cagatgttca ttggagatgg 950

 tgccaagcta gtccgggatg cctttgccct ggccaaggag aaagcgccct 1000

 ctatcatctt cattgatgag ttggatgcca tcggcaccaa gcgctttgac 1050

 agtgagaagg ctggggaccg ggaggtgcag aggacaatgc tggagcttct 1100

 gaaccagctg gatggcttcc agcccaacac ccaagttaag gtaattgcag 1150

 ccacaaacag ggtggacatc ctggaccccg ccctcctccg ctcgggccgc 1200

 cttgaccgca agatagagtt cccgatgccc aatgaggagg cccgggccag 1250

 aatcatgcag atccactccc gaaagatgaa tgtcagtcct gacgtgaact 1300

 acgaggagct ggcccgctgc acagatgact tcaatggggc ccagtgcaag 1350

 gctgtgtgtg tggaggcggg catgatcgca ctgcgcaggg gtgccacgga 1400

 gctcacccac gaggactaca tggaaggcat cctggaggtg caggccaaga 1450

 agaaagccaa cctacaatac tacgcctagg gcacacaggc cagccccagt 1500

 ctcacggctg aagtgcgcaa taaaagatgg tttagggtcc ctgccaaaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1583

<210> 5512
<211> 439
<212> PRT
<213> Homo sapien

<400> 5512
 Met Asn Leu Leu Pro Asn Ile Glu Ser Pro Val Thr Arg Gln Glu
   1               5                  10                  15

 Lys Met Ala Thr Val Trp Asp Glu Ala Glu Gln Asp Gly Ile Gly
                  20                  25                  30

 Glu Glu Val Leu Lys Met Ser Thr Glu Glu Ile Ile Gln Arg Thr
                  35                  40                  45

 Arg Leu Leu Asp Ser Glu Ile Lys Ile Met Lys Ser Glu Val Leu
                  50                  55                  60

 Arg Val Thr His Glu Leu Gln Ala Met Lys Asp Lys Ile Lys Glu
                  65                  70                  75

 Asn Ser Glu Lys Ile Lys Val Asn Lys Thr Leu Pro Tyr Leu Val
                  80                  85                  90

 Ser Asn Val Ile Glu Leu Leu Asp Val Asp Pro Asn Asp Gln Glu
                  95                 100                 105

 Glu Asp Gly Ala Asn Ile Asp Leu Asp Ser Gln Arg Lys Gly Lys
                 110                 115                 120

 Cys Ala Val Ile Lys Thr Ser Thr Arg Gln Thr Tyr Phe Leu Pro
                 125                 130                 135

 Val Ile Gly Leu Val Asp Ala Glu Lys Leu Lys Pro Gly Asp Leu
                 140                 145                 150

 Val Gly Val Asn Lys Asp Ser Tyr Leu Ile Leu Glu Thr Leu Pro
                 155                 160                 165

 Thr Glu Tyr Asp Ser Arg Val Lys Ala Met Glu Val Asp Glu Arg
                 170                 175                 180

 Pro Thr Glu Gln Tyr Ser Asp Ile Gly Gly Leu Asp Lys Gln Ile
                 185                 190                 195

 Gln Glu Leu Val Glu Ala Ile Val Leu Pro Met Asn His Lys Glu
                 200                 205                 210

 Lys Phe Glu Asn Leu Gly Ile Gln Pro Pro Lys Gly Val Leu Met
                 215                 220                 225

 Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu Leu Ala Arg Ala Cys
                 230                 235                 240

 Ala Ala Gln Thr Lys Ala Thr Phe Leu Lys Leu Ala Gly Pro Gln
                 245                 250                 255

 Leu Val Gln Met Phe Ile Gly Asp Gly Ala Lys Leu Val Arg Asp
                 260                 265                 270

 Ala Phe Ala Leu Ala Lys Glu Lys Ala Pro Ser Ile Ile Phe Ile
                 275                 280                 285

 Asp Glu Leu Asp Ala Ile Gly Thr Lys Arg Phe Asp Ser Glu Lys
                 290                 295                 300

 Ala Gly Asp Arg Glu Val Gln Arg Thr Met Leu Glu Leu Leu Asn
                 305                 310                 315

 Gln Leu Asp Gly Phe Gln Pro Asn Thr Gln Val Lys Val Ile Ala
                 320                 325                 330

 Ala Thr Asn Arg Val Asp Ile Leu Asp Pro Ala Leu Leu Arg Ser
                 335                 340                 345

 Gly Arg Leu Asp Arg Lys Ile Glu Phe Pro Met Pro Asn Glu Glu
                 350                 355                 360

 Ala Arg Ala Arg Ile Met Gln Ile His Ser Arg Lys Met Asn Val
                 365                 370                 375

 Ser Pro Asp Val Asn Tyr Glu Glu Leu Ala Arg Cys Thr Asp Asp
                 380                 385                 390

 Phe Asn Gly Ala Gln Cys Lys Ala Val Cys Val Glu Ala Gly Met
                 395                 400                 405

 Ile Ala Leu Arg Arg Gly Ala Thr Glu Leu Thr His Glu Asp Tyr
                 410                 415                 420

 Met Glu Gly Ile Leu Glu Val Gln Ala Lys Lys Lys Ala Asn Leu
                 425                 430                 435

 Gln Tyr Tyr Ala


<210> 5513
<211> 5982
<212> DNA
<213> Homo sapien

<400> 5513
 cgagcatgga gagctgccgc cgcggccggc cggcgacgct ggcgacgctt 50

 tcgcccctga ggtagtttgg cgaccgcgaa gaaggaaaaa gggcgggcgg 100

 gcggctgtcc tctcaccgtc ctcaccccgc gaggcccggc ccgctcctcc 150

 gtcgtggatt tcgcggcgat ccccccggca gctctttgca aagctgcttg 200

 aaacttctcc caaactcggc atggatacga ctgcggcggc ggcgctgcct 250

 gcttttgtgg cgctcttgct cctctctcct tggcctctcc tgggatcggc 300

 ccaaggccag ttctccgcag gtggctgtac ttttgatgat ggtccagggg 350

 cctgtgatta ccaccaggat ctgtatgatg actttgaatg ggtgcatgtt 400

 agtgctcaag agcctcatta tctaccaccc gagatgcccc aaggttccta 450

 tatgatagtg gactcttcag atcacgaccc tggagaaaaa gccagacttc 500

 agctgcctac aatgaaggag aacgacactc actgcattga tttcagttac 550

 ctattatata gccagaaagg actgaatcct ggcactttga acatattagt 600

 tagggtgaat aaaggacctc ttgccaatcc aatttggaat gtgactggat 650

 tcacgggtag agattggctt cgggctgagc tagcagtgag caccttttgg 700

 cccaatgaat atcaggtaat atttgaagct gaagtctcag gagggagaag 750

 tggttatatt gccattgatg acatccaagt actgagttat ccttgtgata 800

 aatctcctca tttcctccgt ctaggggatg tagaggtgaa tgcagggcaa 850

 aacgctacat ttcagtgcat tgccacaggg agagatgctg tgcataacaa 900

 gttatggctc cagagacgaa atggagaaga tataccagta gcccagacta 950

 agaacatcaa tcatagaagg tttgccgctt ccttcagatt gcaagaagtg 1000

 acaaaaactg accaggattt gtatcgctgt gtaactcagt cagaacgagg 1050

 ttccggtgtg tccaattttg ctcaacttat tgtgagagaa ccgccaagac 1100

 ccattgctcc tcctcagctt cttggtgttg ggcctacata tttgctgatc 1150

 caactaaatg ccaactcgat cattggcgat ggtcctatca tcctgaaaga 1200

 agtagagtac cgaatgacat caggatcctg gacagaaacc catgcagtca 1250

 atgctccaac ttacaaatta tggcatttag atccagatac cgaatatgag 1300

 atccgagttc tacttacaag acctggtgaa ggtggaacgg ggctcccagg 1350

 acctccacta atcaccagaa caaaatgtgc agaacctatg agaaccccaa 1400

 agacattaaa gattgctgaa atacaggcaa gacggattgc tgtggactgg 1450

 gaatccttgg gttacaacat tacgcgttgc cacactttta atgtcactat 1500

 ctgctaccat tacttccgtg gtcacaacga gagcaaggca gactgtttgg 1550

 acatggaccc caaagcccct cagcatgttg tgaaccatct gccaccttat 1600

 acaaatgtca gcctcaagat gatcctaacc aatccagagg gaaggaagga 1650

 gagtgaagag acaattattc aaactgatga agatgtgcct ggtcccgtac 1700

 cagtaaaatc tcttcaagga acatcctttg aaaataagat cttcttgaac 1750

 tggaaagaac ctttggatcc aaatggaatc atcactcaat atgagatcag 1800

 ctatagcagt ataagatcat ttgatcctgc agttccagtg gctggacctc 1850

 cccagactgt atcaaattta tggaacagta cacaccatgt ctttatgcat 1900

 ctccaccctg gaaccacgta ccagtttttc ataagagcca gcacggtcaa 1950

 aggctttggt ccagccacag ccatcaatgt caccaccaat atctcagctc 2000

 caactttacc tgactatgaa ggagttgatg cctctctcaa tgaaactgcc 2050

 accacaataa ctgtattgtt gagaccagca caagccaaag gtgctcctat 2100

 cagtgcttat cagattgttg tggaagaact gcacccacac cgaaccaaga 2150

 gagaagccgg agccatggaa tgctaccagg ttcctgtcac ataccaaaat 2200

 gccatgagtg ggggtgcacc gtattacttt gctgcagaac tccccccggg 2250

 aaacctacct gagcctgccc cgttcactgt gggtgacaat cggacctacc 2300

 aaggcttttg gaaccctcct ttggctccgc gcaaaggata caacatctat 2350

 ttccaggcga tgagcagtgt ggagaaggaa actaaaaccc agtgcgtacg 2400

 cattgctaca aaagcagcag caacagaaga accagaagtg atcccagatc 2450

 ccgccaagca gacagacaga gtggtgaaaa tagcaggaat tagtgctgga 2500

 attttggtgt tcatcctcct tctcctagtt gtcatattaa ttgtaaaaaa 2550

 gagcaaactt gctaaaaaac gcaaagatgc catggggaat acccggcagg 2600

 agatgactca catggtgaat gcaatggatc gaagttatgc tgatcagagc 2650

 actctgcatg cagaagatcc tctttccatc accttcatgg accaacataa 2700

 ctttagtcca agatatgaga accacagtgc tacagcagag tccagtcgcc 2750

 ttctagacgt acctcgctac ctctgtgagg ggacggaatc cccttaccag 2800

 acaggacagc tgcatccagc catcagggta gctgatttac tgcagcacat 2850

 taatctcatg aagacatcag acagctatgg gttcaaagag gaatatgaga 2900

 gcttttttga aggacagtca gcatcttggg atgtagctaa aaaagatcaa 2950

 aatagagcaa aaaaccgata tggaaacatt atagcatatg atcactccag 3000

 agtgattttg caacccgtag aggatgatcc ttcctcagat tatattaatg 3050

 ccaactatat tgatggctac cagagaccaa gtcattacat tgcaacccaa 3100

 ggtcccgttc atgaaacagt gtatgatttc tggaggatga tttggcaaga 3150

 acaatctgct tgcattgtga tggttacaaa tttagttgag gttggccggg 3200

 ttaaatgcta taaatattgg cctgatgata ctgaagttta tggtgacttc 3250

 aaagtaacgt gtgtagaaat ggaaccactt gctgaatatg tagttaggac 3300

 attcaccctg gaaaggaggg ggtacaatga aatccgtgaa gttaaacagt 3350

 tccatttcac gggctggcct gaccatggag tgccctacca tgctacaggg 3400

 ctgctttcct ttatccggcg agtcaagtta tcaaaccctc ccagtgctgg 3450

 ccccatcgtt gtacattgca gtgctggtgc tggacgaact ggctgctaca 3500

 ttgtgattga catcatgcta gacatggctg aaagagaggg tgttgttgat 3550

 atttacaatt gtgtcaaagc cttaagatct cggcgtatta atatggtcca 3600

 gacagaggaa cagtacattt ttattcatga tgccatttta gaagcctgct 3650

 tatgtggaga aactgccata cctgtctgtg aatttaaagc tgcatatttt 3700

 gatatgatta gaatagactc ccagactaac tcttcacatc tcaaggatga 3750

 atttcagact ctgaattcag tcacccctcg actacaagct gaagactgca 3800

 gtatagcgtg cctgccaagg aaccatgaca agaaccgttt catggacatg 3850

 ctgccacctg acagatgtct gcctttttta attacaattg atggggagag 3900

 cagtaactac atcaatgctg ctcttatgga cagctacagg caaccagctg 3950

 ctttcatcgt cacacaatac cctctgccaa acactgtaaa agacttctgg 4000

 agattagtgt atgattatgg ctgtacctcc attgtgatgt taaacgaagt 4050

 cgacttgtcc cagggctgcc ctcagtactg gccagaggaa gggatgctac 4100

 gatatggccc catccaagtg gaatgtatgt cttgttcaat ggactgtgat 4150

 gtgatcaacc ggatttttag gatatgcaat ctaacaagac cacaggaagg 4200

 ttatctgatg gtgcaacagt ttcagtacct aggatgggct tctcatcgag 4250

 aagtgcctgg atccaaaagg tcattcttga aactgatact tcaggtggaa 4300

 aagtggcagg aggaatgcga ggaaggggaa ggccggacga ttatccactg 4350

 cctaaatggt ggcgggcgaa gtggcatgtt ctgtgctata ggcatcgttg 4400

 ttgaaatggt gaaacggcaa aatgttgtcg atgttttcca tgcagtaaag 4450

 acactgagga acagcaagcc aaacatggtg gaagccccgg agcaataccg 4500

 tttctgctat gatgtagctt tggagtacct ggaatcatct tagttgggtg 4550

 agactcttta aagtgcatcc atgaagaaac ctgtccatct attgagccag 4600

 cagctgttgt acctgttaca cttgtgcaga aagattttaa tgtggggggt 4650

 gggagacttt tacatttgag aggtaaaagt atttttttta tgaagttgtg 4700

 tatcttaata aaaaggactg aattagtttt tattactata ttaaagcatc 4750

 aacatttcat gccacataaa ttatatttaa taagaaccag attgaaatga 4800

 gaacgtattg gtgtttgtac agtgaacatg ccaccttttt tctcatggtt 4850

 tcagtagagc agctaccaca tgttgcatga gttcatactt tctacgtggc 4900

 atttttctcc ctttctaaaa tgaaagctga tgaatcttaa aaggaagaag 4950

 aaaagaaaag ctgtgcaaat tcatagtaaa gttcgttttt tatatgtttc 5000

 cagtgtagca gatctctata taaatatata aatatatata actggcttat 5050

 tttcttttaa tgtgcaatga tggctggatc atttaaagtt ctttttagaa 5100

 aataacataa gccaaagact caagtgtaaa tatgtctata tggagaaagc 5150

 acattatatt tattggttac ttacattcct tttttgatgg ctaaaatact 5200

 accaccacac aatcatcttt ttttcctgaa gaaagctttt tctttagcta 5250

 aaatcaattg taaacgattt ttgtagatta ttttttgtat gttttagtgt 5300

 aagtagaaga taaacttttt attcataaac caggaagcaa tgttctttat 5350

 agtgattctc ttgtgtacat gcttgtgaat taaatttgtg taaaatccct 5400

 tggcaattgg gtcttttaat ataggaccaa attaaaacat tttgctgaat 5450

 atgtatagtt tttcacaatt tcattaggta aataatggtt tggtgatcat 5500

 acatgagaaa tgtacacatt aaaaggcctt gctgacaact tgcacaatgt 5550

 tgaacatagc ctttaagcat catttaaatt ttaaaggaat ggagtttttc 5600

 agcctgtggc ccagcactgg tcaagaaaac aagatggcaa catatatgct 5650

 ttcagggtca aatttgagca aactgtaaac tgtcagggtg ataaaatgtt 5700

 tctcttgatg tttacatgca caagctttgc gttctgacta taaaaagtgt 5750

 gaacaaatca atgccagatt cctgttttgc gcattgtcat gggattctta 5800

 agtgaacctt tctaaatgtg gtcttgttca catgctccac gtagctgtaa 5850

 cttcacatca tcagcttgca gtttgtaatt gactaaagca ttccagtgtc 5900

 ctctttctag attgccagct catgacatgg tgcttataaa gatttaatta 5950

 aagtaagaat gaaataaagt ttttataatt at 5982

<210> 5514
<211> 1440
<212> PRT
<213> Homo sapien

<400> 5514
 Met Asp Thr Thr Ala Ala Ala Ala Leu Pro Ala Phe Val Ala Leu
   1               5                  10                  15

 Leu Leu Leu Ser Pro Trp Pro Leu Leu Gly Ser Ala Gln Gly Gln
                  20                  25                  30

 Phe Ser Ala Gly Gly Cys Thr Phe Asp Asp Gly Pro Gly Ala Cys
                  35                  40                  45

 Asp Tyr His Gln Asp Leu Tyr Asp Asp Phe Glu Trp Val His Val
                  50                  55                  60

 Ser Ala Gln Glu Pro His Tyr Leu Pro Pro Glu Met Pro Gln Gly
                  65                  70                  75

 Ser Tyr Met Ile Val Asp Ser Ser Asp His Asp Pro Gly Glu Lys
                  80                  85                  90

 Ala Arg Leu Gln Leu Pro Thr Met Lys Glu Asn Asp Thr His Cys
                  95                 100                 105

 Ile Asp Phe Ser Tyr Leu Leu Tyr Ser Gln Lys Gly Leu Asn Pro
                 110                 115                 120

 Gly Thr Leu Asn Ile Leu Val Arg Val Asn Lys Gly Pro Leu Ala
                 125                 130                 135

 Asn Pro Ile Trp Asn Val Thr Gly Phe Thr Gly Arg Asp Trp Leu
                 140                 145                 150

 Arg Ala Glu Leu Ala Val Ser Thr Phe Trp Pro Asn Glu Tyr Gln
                 155                 160                 165

 Val Ile Phe Glu Ala Glu Val Ser Gly Gly Arg Ser Gly Tyr Ile
                 170                 175                 180

 Ala Ile Asp Asp Ile Gln Val Leu Ser Tyr Pro Cys Asp Lys Ser
                 185                 190                 195

 Pro His Phe Leu Arg Leu Gly Asp Val Glu Val Asn Ala Gly Gln
                 200                 205                 210

 Asn Ala Thr Phe Gln Cys Ile Ala Thr Gly Arg Asp Ala Val His
                 215                 220                 225

 Asn Lys Leu Trp Leu Gln Arg Arg Asn Gly Glu Asp Ile Pro Val
                 230                 235                 240

 Ala Gln Thr Lys Asn Ile Asn His Arg Arg Phe Ala Ala Ser Phe
                 245                 250                 255

 Arg Leu Gln Glu Val Thr Lys Thr Asp Gln Asp Leu Tyr Arg Cys
                 260                 265                 270

 Val Thr Gln Ser Glu Arg Gly Ser Gly Val Ser Asn Phe Ala Gln
                 275                 280                 285

 Leu Ile Val Arg Glu Pro Pro Arg Pro Ile Ala Pro Pro Gln Leu
                 290                 295                 300

 Leu Gly Val Gly Pro Thr Tyr Leu Leu Ile Gln Leu Asn Ala Asn
                 305                 310                 315

 Ser Ile Ile Gly Asp Gly Pro Ile Ile Leu Lys Glu Val Glu Tyr
                 320                 325                 330

 Arg Met Thr Ser Gly Ser Trp Thr Glu Thr His Ala Val Asn Ala
                 335                 340                 345

 Pro Thr Tyr Lys Leu Trp His Leu Asp Pro Asp Thr Glu Tyr Glu
                 350                 355                 360

 Ile Arg Val Leu Leu Thr Arg Pro Gly Glu Gly Gly Thr Gly Leu
                 365                 370                 375

 Pro Gly Pro Pro Leu Ile Thr Arg Thr Lys Cys Ala Glu Pro Met
                 380                 385                 390

 Arg Thr Pro Lys Thr Leu Lys Ile Ala Glu Ile Gln Ala Arg Arg
                 395                 400                 405

 Ile Ala Val Asp Trp Glu Ser Leu Gly Tyr Asn Ile Thr Arg Cys
                 410                 415                 420

 His Thr Phe Asn Val Thr Ile Cys Tyr His Tyr Phe Arg Gly His
                 425                 430                 435

 Asn Glu Ser Lys Ala Asp Cys Leu Asp Met Asp Pro Lys Ala Pro
                 440                 445                 450

 Gln His Val Val Asn His Leu Pro Pro Tyr Thr Asn Val Ser Leu
                 455                 460                 465

 Lys Met Ile Leu Thr Asn Pro Glu Gly Arg Lys Glu Ser Glu Glu
                 470                 475                 480

 Thr Ile Ile Gln Thr Asp Glu Asp Val Pro Gly Pro Val Pro Val
                 485                 490                 495

 Lys Ser Leu Gln Gly Thr Ser Phe Glu Asn Lys Ile Phe Leu Asn
                 500                 505                 510

 Trp Lys Glu Pro Leu Asp Pro Asn Gly Ile Ile Thr Gln Tyr Glu
                 515                 520                 525

 Ile Ser Tyr Ser Ser Ile Arg Ser Phe Asp Pro Ala Val Pro Val
                 530                 535                 540

 Ala Gly Pro Pro Gln Thr Val Ser Asn Leu Trp Asn Ser Thr His
                 545                 550                 555

 His Val Phe Met His Leu His Pro Gly Thr Thr Tyr Gln Phe Phe
                 560                 565                 570

 Ile Arg Ala Ser Thr Val Lys Gly Phe Gly Pro Ala Thr Ala Ile
                 575                 580                 585

 Asn Val Thr Thr Asn Ile Ser Ala Pro Thr Leu Pro Asp Tyr Glu
                 590                 595                 600

 Gly Val Asp Ala Ser Leu Asn Glu Thr Ala Thr Thr Ile Thr Val
                 605                 610                 615

 Leu Leu Arg Pro Ala Gln Ala Lys Gly Ala Pro Ile Ser Ala Tyr
                 620                 625                 630

 Gln Ile Val Val Glu Glu Leu His Pro His Arg Thr Lys Arg Glu
                 635                 640                 645

 Ala Gly Ala Met Glu Cys Tyr Gln Val Pro Val Thr Tyr Gln Asn
                 650                 655                 660

 Ala Met Ser Gly Gly Ala Pro Tyr Tyr Phe Ala Ala Glu Leu Pro
                 665                 670                 675

 Pro Gly Asn Leu Pro Glu Pro Ala Pro Phe Thr Val Gly Asp Asn
                 680                 685                 690

 Arg Thr Tyr Gln Gly Phe Trp Asn Pro Pro Leu Ala Pro Arg Lys
                 695                 700                 705

 Gly Tyr Asn Ile Tyr Phe Gln Ala Met Ser Ser Val Glu Lys Glu
                 710                 715                 720

 Thr Lys Thr Gln Cys Val Arg Ile Ala Thr Lys Ala Ala Ala Thr
                 725                 730                 735

 Glu Glu Pro Glu Val Ile Pro Asp Pro Ala Lys Gln Thr Asp Arg
                 740                 745                 750

 Val Val Lys Ile Ala Gly Ile Ser Ala Gly Ile Leu Val Phe Ile
                 755                 760                 765

 Leu Leu Leu Leu Val Val Ile Leu Ile Val Lys Lys Ser Lys Leu
                 770                 775                 780

 Ala Lys Lys Arg Lys Asp Ala Met Gly Asn Thr Arg Gln Glu Met
                 785                 790                 795

 Thr His Met Val Asn Ala Met Asp Arg Ser Tyr Ala Asp Gln Ser
                 800                 805                 810

 Thr Leu His Ala Glu Asp Pro Leu Ser Ile Thr Phe Met Asp Gln
                 815                 820                 825

 His Asn Phe Ser Pro Arg Tyr Glu Asn His Ser Ala Thr Ala Glu
                 830                 835                 840

 Ser Ser Arg Leu Leu Asp Val Pro Arg Tyr Leu Cys Glu Gly Thr
                 845                 850                 855

 Glu Ser Pro Tyr Gln Thr Gly Gln Leu His Pro Ala Ile Arg Val
                 860                 865                 870

 Ala Asp Leu Leu Gln His Ile Asn Leu Met Lys Thr Ser Asp Ser
                 875                 880                 885

 Tyr Gly Phe Lys Glu Glu Tyr Glu Ser Phe Phe Glu Gly Gln Ser
                 890                 895                 900

 Ala Ser Trp Asp Val Ala Lys Lys Asp Gln Asn Arg Ala Lys Asn
                 905                 910                 915

 Arg Tyr Gly Asn Ile Ile Ala Tyr Asp His Ser Arg Val Ile Leu
                 920                 925                 930

 Gln Pro Val Glu Asp Asp Pro Ser Ser Asp Tyr Ile Asn Ala Asn
                 935                 940                 945

 Tyr Ile Asp Gly Tyr Gln Arg Pro Ser His Tyr Ile Ala Thr Gln
                 950                 955                 960

 Gly Pro Val His Glu Thr Val Tyr Asp Phe Trp Arg Met Ile Trp
                 965                 970                 975

 Gln Glu Gln Ser Ala Cys Ile Val Met Val Thr Asn Leu Val Glu
                 980                 985                 990

 Val Gly Arg Val Lys Cys Tyr Lys Tyr Trp Pro Asp Asp Thr Glu
                 995                1000                1005

 Val Tyr Gly Asp Phe Lys Val Thr Cys Val Glu Met Glu Pro Leu
                1010                1015                1020

 Ala Glu Tyr Val Val Arg Thr Phe Thr Leu Glu Arg Arg Gly Tyr
                1025                1030                1035

 Asn Glu Ile Arg Glu Val Lys Gln Phe His Phe Thr Gly Trp Pro
                1040                1045                1050

 Asp His Gly Val Pro Tyr His Ala Thr Gly Leu Leu Ser Phe Ile
                1055                1060                1065

 Arg Arg Val Lys Leu Ser Asn Pro Pro Ser Ala Gly Pro Ile Val
                1070                1075                1080

 Val His Cys Ser Ala Gly Ala Gly Arg Thr Gly Cys Tyr Ile Val
                1085                1090                1095

 Ile Asp Ile Met Leu Asp Met Ala Glu Arg Glu Gly Val Val Asp
                1100                1105                1110

 Ile Tyr Asn Cys Val Lys Ala Leu Arg Ser Arg Arg Ile Asn Met
                1115                1120                1125

 Val Gln Thr Glu Glu Gln Tyr Ile Phe Ile His Asp Ala Ile Leu
                1130                1135                1140

 Glu Ala Cys Leu Cys Gly Glu Thr Ala Ile Pro Val Cys Glu Phe
                1145                1150                1155

 Lys Ala Ala Tyr Phe Asp Met Ile Arg Ile Asp Ser Gln Thr Asn
                1160                1165                1170

 Ser Ser His Leu Lys Asp Glu Phe Gln Thr Leu Asn Ser Val Thr
                1175                1180                1185

 Pro Arg Leu Gln Ala Glu Asp Cys Ser Ile Ala Cys Leu Pro Arg
                1190                1195                1200

 Asn His Asp Lys Asn Arg Phe Met Asp Met Leu Pro Pro Asp Arg
                1205                1210                1215

 Cys Leu Pro Phe Leu Ile Thr Ile Asp Gly Glu Ser Ser Asn Tyr
                1220                1225                1230

 Ile Asn Ala Ala Leu Met Asp Ser Tyr Arg Gln Pro Ala Ala Phe
                1235                1240                1245

 Ile Val Thr Gln Tyr Pro Leu Pro Asn Thr Val Lys Asp Phe Trp
                1250                1255                1260

 Arg Leu Val Tyr Asp Tyr Gly Cys Thr Ser Ile Val Met Leu Asn
                1265                1270                1275

 Glu Val Asp Leu Ser Gln Gly Cys Pro Gln Tyr Trp Pro Glu Glu
                1280                1285                1290

 Gly Met Leu Arg Tyr Gly Pro Ile Gln Val Glu Cys Met Ser Cys
                1295                1300                1305

 Ser Met Asp Cys Asp Val Ile Asn Arg Ile Phe Arg Ile Cys Asn
                1310                1315                1320

 Leu Thr Arg Pro Gln Glu Gly Tyr Leu Met Val Gln Gln Phe Gln
                1325                1330                1335

 Tyr Leu Gly Trp Ala Ser His Arg Glu Val Pro Gly Ser Lys Arg
                1340                1345                1350

 Ser Phe Leu Lys Leu Ile Leu Gln Val Glu Lys Trp Gln Glu Glu
                1355                1360                1365

 Cys Glu Glu Gly Glu Gly Arg Thr Ile Ile His Cys Leu Asn Gly
                1370                1375                1380

 Gly Gly Arg Ser Gly Met Phe Cys Ala Ile Gly Ile Val Val Glu
                1385                1390                1395

 Met Val Lys Arg Gln Asn Val Val Asp Val Phe His Ala Val Lys
                1400                1405                1410

 Thr Leu Arg Asn Ser Lys Pro Asn Met Val Glu Ala Pro Glu Gln
                1415                1420                1425

 Tyr Arg Phe Cys Tyr Asp Val Ala Leu Glu Tyr Leu Glu Ser Ser
                1430                1435                1440

<210> 5515
<211> 3423
<212> DNA
<213> Homo sapien

<400> 5515
 cggctcgctg gtaccggcag tgccatggcg gccttcagca agtacttgac 50

 ggcgcggaac tcctcgctgg ctggtgccgc gttcctgctg ctctgcctgc 100

 tccacaagcg gcgccgcgcc ctcggcctgc acggtaagaa aagtggaaaa 150

 ccaccattac agaacaatga gaaagagggg aaaaaagagc gagctgtggt 200

 ggacaaggtg tttttctcaa ggctcataca gattctgaaa atcatggtcc 250

 ctagaacatt ttgtaaagag acaggttact tggtacttat tgctgttatg 300

 ctggtgtctc gaacatattg tgatgtttgg atgattcaaa atgggacact 350

 aattgaaagt ggtatcattg gtcgtagcag gaaagatttc aagagatact 400

 tactcaactt catcgctgcc atgcctctta tctctctggt taataacttc 450

 ttgaagtatg ggttaaatga gcttaaactg tgcttccgag taaggctcac 500

 taaatacctc tatgaggagt atcttcaagc tttcacatat tataaaatgg 550

 ggaatctgga caacagaata gctaatccag accagctgct tacacaagat 600

 gtagaaaaat tttgtaacag tgtagtcgat ctgtattcaa atcttagtaa 650

 gccattttta gacatagttt tgtatatctt taagttaacg agtgcaattg 700

 gagctcaggg cccagcgagc atgatggcct acttggttgt ttctgggcta 750

 ttcctaactc gacttcgaag acccattggt aagatgacaa taactgagca 800

 aaagtatgaa ggagaatata gatatgttaa ttctcggctc atcacaaaca 850

 gtgaagaaat tgccttttac aatgggaata aaagagaaaa gcagacagtc 900

 cactcagtct tccgaaaact ggtggaacac ctacataatt tcattttgtt 950

 tcggttttca atgggcttca ttgatagtat tattgccaaa taccttgcca 1000

 ctgttgttgg ttacctagtt gtcagtcgcc ctttcttaga tttgtctcat 1050

 cctcgacatc tcaagagtac acattcggaa cttctagagg attactacca 1100

 aagtggaaga atgcttttgc gaatgtctca agctctgggt cgaatagttt 1150

 tggctgggcg tgaaatgact agattggccg gttttactgc tcggattaca 1200

 gaattaatgc aagtactgaa ggatttaaat catggcaaat atgagcgcac 1250

 aatggtctca caacaggaaa agggtattga aggagtacaa gtcattccct 1300

 tgatacctgg tgctggagaa atcattattg cagataacat tataaagttt 1350

 gatcatgttc ctttagcaac gccaaatgga gatgttttga tccgagacct 1400

 taattttgaa gttcgatctg gggctaatgt tctaatttgt ggtccaaatg 1450

 gctgcggaaa gagttcactt ttccgtgttc ttggtgaatt atggcctctt 1500

 tttggaggac gtctaactaa acctgaaaga ggaaaattat tttatgttcc 1550

 tcagagacct tacatgaccc ttggaacact tcgagatcaa gtgatatatc 1600

 cagatggacg agaagatcag aaaaggaagg gaatttctga cctagtactg 1650

 aaggaatact tagacaatgt ccagttgggt catatccttg aacgtgaagg 1700

 aggctgggac agtgttcagg attggatgga cgtactcagt ggtggagaaa 1750

 agcaaagaat ggcgatggca agattatttt atcataaacc ccagtttgcc 1800

 attttggatg aatgcacaag tgcagttagt gtcgacgtgg aaggctacat 1850

 ttatagtcat tgtcgaaagg ttggcatcac tctcttcact gtgtctcata 1900

 ggaaatctct ttggaaacat catgagtact acctgcatat ggatggcaga 1950

 ggcaactatg aattcaaaca gataacagaa gatacagttg agtttggctc 2000

 ttagagaaat ctggagaact atacctgctt cagtgaaata attacagaat 2050

 atacttagaa aggcaaagta cattgtaaaa taaagttgag cttagttttt 2100

 tttaaaaaaa aaaaacaaag caacaaatta actagataca gaataatgga 2150

 gaacaagttg ttaaaacatt taatattata taggatattg ctaattgtgt 2200

 atatgttggt ttaattaata atatgtacta agaatgtcct tattcttgtg 2250

 gttaaaaacc tgcctaaatt aaattgggct tcaatcactg taacctgatt 2300

 catcctggga tgtaaaccat tcgaagtcag ctaattggac ttttatggct 2350

 ctatcttttc cttcagtgaa gaaccctatt taaaactggg tcatcatttg 2400

 tcctgttcta gcaagatagt cttcagtttc attttcctgt gccctgtggt 2450

 agttggaaac aaatcataat gtattattta aatgtttaac atcattgcat 2500

 aacagcgttt attatacagt ggcagatttc tttagctgcc acagtaatac 2550

 tcattccttg tgtgtgtctt ggagtgcatt tgactccagg aaaagccatt 2600

 ttggttttcc ttaactaaat gataaatgta cccctctcag tctgcagtat 2650

 tgagttgttt aaagtatatg tgcagtcttg cttacaagga ggggttacca 2700

 tgtatcacac ctaatcttcc caatgtttgg gatattaaaa cacaaagtcc 2750

 ttaacatgcc aggctcaagg tcttataaga gttctagatt tttaagagaa 2800

 ttagacaaat ttgtgtgtgt tagaagccca ttcattagaa gtgtggtggt 2850

 tatttggtat taaactccaa atgagccata ggaaggcact acatgaaata 2900

 atgcactgag tatgcaatgc tatcactgtc tttgactgtg attttatgtt 2950

 taaaaagtat gttctaaaat tattatatat acatgggtga attatgtttc 3000

 cgaggcactg ttttatctct gtgaatcttg aataactttt ttatatttgg 3050

 gttatgatgt caaacgatcc taagcgaaga tgatttcagt tcatcaaatc 3100

 atcattaatg actttatgta ttatttgcac agggagaatt gaaactgagt 3150

 ataatcaata agctagatac gaaatcagtt tctcaaactg agcttcagaa 3200

 aggggcattt tgtactcttg tttttgcata actggttttg tttttttgca 3250

 gaattaacta taacaatcac tggctaccga agtaaactga tgtactgaat 3300

 tccataatac ataacattca atttttacca cttctgttta gcgaacttgt 3350

 atacttattt tctgttcaga ttaaaaaaaa aaaaaaaaaa aactcagata 3400

 tcctataaaa aaaaaaggaa ttc 3423

<210> 5516
<211> 659
<212> PRT
<213> Homo sapien

<400> 5516
 Met Ala Ala Phe Ser Lys Tyr Leu Thr Ala Arg Asn Ser Ser Leu
   1               5                  10                  15

 Ala Gly Ala Ala Phe Leu Leu Leu Cys Leu Leu His Lys Arg Arg
                  20                  25                  30

 Arg Ala Leu Gly Leu His Gly Lys Lys Ser Gly Lys Pro Pro Leu
                  35                  40                  45

 Gln Asn Asn Glu Lys Glu Gly Lys Lys Glu Arg Ala Val Val Asp
                  50                  55                  60

 Lys Val Phe Phe Ser Arg Leu Ile Gln Ile Leu Lys Ile Met Val
                  65                  70                  75

 Pro Arg Thr Phe Cys Lys Glu Thr Gly Tyr Leu Val Leu Ile Ala
                  80                  85                  90

 Val Met Leu Val Ser Arg Thr Tyr Cys Asp Val Trp Met Ile Gln
                  95                 100                 105

 Asn Gly Thr Leu Ile Glu Ser Gly Ile Ile Gly Arg Ser Arg Lys
                 110                 115                 120

 Asp Phe Lys Arg Tyr Leu Leu Asn Phe Ile Ala Ala Met Pro Leu
                 125                 130                 135

 Ile Ser Leu Val Asn Asn Phe Leu Lys Tyr Gly Leu Asn Glu Leu
                 140                 145                 150

 Lys Leu Cys Phe Arg Val Arg Leu Thr Lys Tyr Leu Tyr Glu Glu
                 155                 160                 165

 Tyr Leu Gln Ala Phe Thr Tyr Tyr Lys Met Gly Asn Leu Asp Asn
                 170                 175                 180

 Arg Ile Ala Asn Pro Asp Gln Leu Leu Thr Gln Asp Val Glu Lys
                 185                 190                 195

 Phe Cys Asn Ser Val Val Asp Leu Tyr Ser Asn Leu Ser Lys Pro
                 200                 205                 210

 Phe Leu Asp Ile Val Leu Tyr Ile Phe Lys Leu Thr Ser Ala Ile
                 215                 220                 225

 Gly Ala Gln Gly Pro Ala Ser Met Met Ala Tyr Leu Val Val Ser
                 230                 235                 240

 Gly Leu Phe Leu Thr Arg Leu Arg Arg Pro Ile Gly Lys Met Thr
                 245                 250                 255

 Ile Thr Glu Gln Lys Tyr Glu Gly Glu Tyr Arg Tyr Val Asn Ser
                 260                 265                 270

 Arg Leu Ile Thr Asn Ser Glu Glu Ile Ala Phe Tyr Asn Gly Asn
                 275                 280                 285

 Lys Arg Glu Lys Gln Thr Val His Ser Val Phe Arg Lys Leu Val
                 290                 295                 300

 Glu His Leu His Asn Phe Ile Leu Phe Arg Phe Ser Met Gly Phe
                 305                 310                 315

 Ile Asp Ser Ile Ile Ala Lys Tyr Leu Ala Thr Val Val Gly Tyr
                 320                 325                 330

 Leu Val Val Ser Arg Pro Phe Leu Asp Leu Ser His Pro Arg His
                 335                 340                 345

 Leu Lys Ser Thr His Ser Glu Leu Leu Glu Asp Tyr Tyr Gln Ser
                 350                 355                 360

 Gly Arg Met Leu Leu Arg Met Ser Gln Ala Leu Gly Arg Ile Val
                 365                 370                 375

 Leu Ala Gly Arg Glu Met Thr Arg Leu Ala Gly Phe Thr Ala Arg
                 380                 385                 390

 Ile Thr Glu Leu Met Gln Val Leu Lys Asp Leu Asn His Gly Lys
                 395                 400                 405

 Tyr Glu Arg Thr Met Val Ser Gln Gln Glu Lys Gly Ile Glu Gly
                 410                 415                 420

 Val Gln Val Ile Pro Leu Ile Pro Gly Ala Gly Glu Ile Ile Ile
                 425                 430                 435

 Ala Asp Asn Ile Ile Lys Phe Asp His Val Pro Leu Ala Thr Pro
                 440                 445                 450

 Asn Gly Asp Val Leu Ile Arg Asp Leu Asn Phe Glu Val Arg Ser
                 455                 460                 465

 Gly Ala Asn Val Leu Ile Cys Gly Pro Asn Gly Cys Gly Lys Ser
                 470                 475                 480

 Ser Leu Phe Arg Val Leu Gly Glu Leu Trp Pro Leu Phe Gly Gly
                 485                 490                 495

 Arg Leu Thr Lys Pro Glu Arg Gly Lys Leu Phe Tyr Val Pro Gln
                 500                 505                 510

 Arg Pro Tyr Met Thr Leu Gly Thr Leu Arg Asp Gln Val Ile Tyr
                 515                 520                 525

 Pro Asp Gly Arg Glu Asp Gln Lys Arg Lys Gly Ile Ser Asp Leu
                 530                 535                 540

 Val Leu Lys Glu Tyr Leu Asp Asn Val Gln Leu Gly His Ile Leu
                 545                 550                 555

 Glu Arg Glu Gly Gly Trp Asp Ser Val Gln Asp Trp Met Asp Val
                 560                 565                 570

 Leu Ser Gly Gly Glu Lys Gln Arg Met Ala Met Ala Arg Leu Phe
                 575                 580                 585

 Tyr His Lys Pro Gln Phe Ala Ile Leu Asp Glu Cys Thr Ser Ala
                 590                 595                 600

 Val Ser Val Asp Val Glu Gly Tyr Ile Tyr Ser His Cys Arg Lys
                 605                 610                 615

 Val Gly Ile Thr Leu Phe Thr Val Ser His Arg Lys Ser Leu Trp
                 620                 625                 630

 Lys His His Glu Tyr Tyr Leu His Met Asp Gly Arg Gly Asn Tyr
                 635                 640                 645

 Glu Phe Lys Gln Ile Thr Glu Asp Thr Val Glu Phe Gly Ser
                 650                 655

<210> 5517
<211> 1764
<212> DNA
<213> Homo sapien

<400> 5517
 atggcctcgg aagacattgc caagctggca gagacacttg ccaagactca 50

 ggtggccggg ggacagctga gtttcaaagg caagagcctc aaactcaaca 100

 ctgcagaaga tgctaaagat gtgattaaag agattgaaga ctttgacagc 150

 ttggaggctc tgcgtctgga aggcaacaca gtgggcgtgg aagcagccag 200

 ggtcatcgcc aaggccttag agaagaagtc ggagttgaag cgctgccact 250

 ggagtgacat gttcacggga aggctgcgga ccgagatccc accagccctg 300

 atctcactag gggaaggact catcacagct ggggctcagc tggtggagct 350

 ggacttaagc gacaacgcat tcgggcccga cggtgtgcaa ggcttcgagg 400

 ccctgctcaa gagctcagcc tgcttcaccc tgcaggaact caagctcaac 450

 aactgtggca tgggcattgg cggcggcaag atcctggctg cagctctgac 500

 cgaatgtcac cggaaatcca gtgcccaagg caagcctctg gccctgaagg 550

 tctttgtggc tggcagaaac cgtctggaga atgatggcgc cactgccttg 600

 gcagaagctt ttagggtcat cgggaccctg gaggaggtcc acatgccaca 650

 gaatgggatc aaccaccctg gcatcactgc cctggcccag gctttcgctg 700

 tcaaccccct gctgcgggtc atcaacctga atgacaacac cttcactgag 750

 aagggcgccg tggccatggc cgagaccttg aagaccttgc ggcaggtgga 800

 ggtgattaat tttggggact gcctggtgcg ctccaagggt gcagttgcca 850

 ttgcagatgc catccgcggc ggcctgccca agctaaagga gctgaacttg 900

 tcattctgtg aaatcaagag ggatgctgcc ctggctgttg ctgaggccat 950

 ggcagacaaa gctgagctgg agaagctgga cctgaatggc aacaccctgg 1000

 gagaagaagg ctgtgaacag cttcaggagg tgctggaggg cttcaacatg 1050

 gccaaggtgc tggcgtccct cagtgatgac gaggacgagg aggaggagga 1100

 ggaaggagaa gaggaagaag aggaagcaga agaagaggag gaggaagatg 1150

 aggaagagga ggaagaagag gaggaggagg aggaagaaga gcctcagcag 1200

 cgagggcagg gagagaagtc agccacgccc tcacggaaga ttctggaccc 1250

 taacactggg gagccagctc ccgtgctgtc ctccccacct cctgcagacg 1300

 tctccacctt cctggctttt ccctctccag agaagctcct gcgcctaggg 1350

 cccaagagct ccgtgctgat agcccagcag actgacacgt ctgaccccga 1400

 gaaggtggtc tctgccttcc taaaggtgtc atctgtgttc aaggacgaag 1450

 ctactgtgag gatggcagtg caggatgcag tagatgccct gatgcagaag 1500

 gctttcaact cctcgtcctt caactccaac accttcctca ccaggctcct 1550

 cgtgcacatg ggtctgctca agagtgaaga caaggtcaag gccattgcca 1600

 acctgtacgg ccccctgatg gcgctgaacc acatggtgca gcaggactat 1650

 ttccccaagg cccttgcacc cctgctgctg gcgttcgtga ccaagcccaa 1700

 cagcgccctg gaatcctgct ccttcgcccg ccacagtctg ctgcagacgc 1750

 tgtacaaggt ctag 1764

<210> 5518
<211> 587
<212> PRT
<213> Homo sapien

<400> 5518
 Met Ala Ser Glu Asp Ile Ala Lys Leu Ala Glu Thr Leu Ala Lys
   1               5                  10                  15

 Thr Gln Val Ala Gly Gly Gln Leu Ser Phe Lys Gly Lys Ser Leu
                  20                  25                  30

 Lys Leu Asn Thr Ala Glu Asp Ala Lys Asp Val Ile Lys Glu Ile
                  35                  40                  45

 Glu Asp Phe Asp Ser Leu Glu Ala Leu Arg Leu Glu Gly Asn Thr
                  50                  55                  60

 Val Gly Val Glu Ala Ala Arg Val Ile Ala Lys Ala Leu Glu Lys
                  65                  70                  75

 Lys Ser Glu Leu Lys Arg Cys His Trp Ser Asp Met Phe Thr Gly
                  80                  85                  90

 Arg Leu Arg Thr Glu Ile Pro Pro Ala Leu Ile Ser Leu Gly Glu
                  95                 100                 105

 Gly Leu Ile Thr Ala Gly Ala Gln Leu Val Glu Leu Asp Leu Ser
                 110                 115                 120

 Asp Asn Ala Phe Gly Pro Asp Gly Val Gln Gly Phe Glu Ala Leu
                 125                 130                 135

 Leu Lys Ser Ser Ala Cys Phe Thr Leu Gln Glu Leu Lys Leu Asn
                 140                 145                 150

 Asn Cys Gly Met Gly Ile Gly Gly Gly Lys Ile Leu Ala Ala Ala
                 155                 160                 165

 Leu Thr Glu Cys His Arg Lys Ser Ser Ala Gln Gly Lys Pro Leu
                 170                 175                 180

 Ala Leu Lys Val Phe Val Ala Gly Arg Asn Arg Leu Glu Asn Asp
                 185                 190                 195

 Gly Ala Thr Ala Leu Ala Glu Ala Phe Arg Val Ile Gly Thr Leu
                 200                 205                 210

 Glu Glu Val His Met Pro Gln Asn Gly Ile Asn His Pro Gly Ile
                 215                 220                 225

 Thr Ala Leu Ala Gln Ala Phe Ala Val Asn Pro Leu Leu Arg Val
                 230                 235                 240

 Ile Asn Leu Asn Asp Asn Thr Phe Thr Glu Lys Gly Ala Val Ala
                 245                 250                 255

 Met Ala Glu Thr Leu Lys Thr Leu Arg Gln Val Glu Val Ile Asn
                 260                 265                 270

 Phe Gly Asp Cys Leu Val Arg Ser Lys Gly Ala Val Ala Ile Ala
                 275                 280                 285

 Asp Ala Ile Arg Gly Gly Leu Pro Lys Leu Lys Glu Leu Asn Leu
                 290                 295                 300

 Ser Phe Cys Glu Ile Lys Arg Asp Ala Ala Leu Ala Val Ala Glu
                 305                 310                 315

 Ala Met Ala Asp Lys Ala Glu Leu Glu Lys Leu Asp Leu Asn Gly
                 320                 325                 330

 Asn Thr Leu Gly Glu Glu Gly Cys Glu Gln Leu Gln Glu Val Leu
                 335                 340                 345

 Glu Gly Phe Asn Met Ala Lys Val Leu Ala Ser Leu Ser Asp Asp
                 350                 355                 360

 Glu Asp Glu Glu Glu Glu Glu Glu Gly Glu Glu Glu Glu Glu Glu
                 365                 370                 375

 Ala Glu Glu Glu Glu Glu Glu Asp Glu Glu Glu Glu Glu Glu Glu
                 380                 385                 390

 Glu Glu Glu Glu Glu Glu Glu Pro Gln Gln Arg Gly Gln Gly Glu
                 395                 400                 405

 Lys Ser Ala Thr Pro Ser Arg Lys Ile Leu Asp Pro Asn Thr Gly
                 410                 415                 420

 Glu Pro Ala Pro Val Leu Ser Ser Pro Pro Pro Ala Asp Val Ser
                 425                 430                 435

 Thr Phe Leu Ala Phe Pro Ser Pro Glu Lys Leu Leu Arg Leu Gly
                 440                 445                 450

 Pro Lys Ser Ser Val Leu Ile Ala Gln Gln Thr Asp Thr Ser Asp
                 455                 460                 465

 Pro Glu Lys Val Val Ser Ala Phe Leu Lys Val Ser Ser Val Phe
                 470                 475                 480

 Lys Asp Glu Ala Thr Val Arg Met Ala Val Gln Asp Ala Val Asp
                 485                 490                 495

 Ala Leu Met Gln Lys Ala Phe Asn Ser Ser Ser Phe Asn Ser Asn
                 500                 505                 510

 Thr Phe Leu Thr Arg Leu Leu Val His Met Gly Leu Leu Lys Ser
                 515                 520                 525

 Glu Asp Lys Val Lys Ala Ile Ala Asn Leu Tyr Gly Pro Leu Met
                 530                 535                 540

 Ala Leu Asn His Met Val Gln Gln Asp Tyr Phe Pro Lys Ala Leu
                 545                 550                 555

 Ala Pro Leu Leu Leu Ala Phe Val Thr Lys Pro Asn Ser Ala Leu
                 560                 565                 570

 Glu Ser Cys Ser Phe Ala Arg His Ser Leu Leu Gln Thr Leu Tyr
                 575                 580                 585

 Lys Val


<210> 5519
<211> 2104
<212> DNA
<213> Homo sapien

<400> 5519
 gctgttgtcg ctcgctcagc gtctccctct cggccgccct ctcctcggga 50

 cgatggcgcg cggtggccgc ggccgccgcc tggggttagc cctggggctg 100

 ctgctggcgc tggtgctggc gccgcgggtt ctgcgggcca agcccacggt 150

 gcgcaaagag cgcgtggtgc ggcccgactc ggagctgggc gagcggcccc 200

 ctgaggacaa ccagagcttc cagtacgacc acgaggcctt cctgggcaag 250

 gaggactcca agaccttcga ccagctcacc ccggacgaga gcaaggagag 300

 gctagggaag attgttgatc gaatcgacaa tgatggggat ggctttgtca 350

 ctactgagga gctgaaaacc tggatcaaac gggtgcagaa aagatacatc 400

 tttgataatg tcgccaaagt ctggaaggat tatgataggg acaaggatga 450

 taaaatttcc tgggaagaat acaaacaagc cacctatggt tactacctag 500

 gaaaccccgc agagtttcat gattcttcag atcatcacac ctttaaaaag 550

 atgctgccac gtgatgagag aagattcaaa gctgcagacc tcaatggtga 600

 cctgacagct actcgggagg agttcactgc ctttctgcat cctgaagagt 650

 ttgaacatat gaaggaaatt gtggttttgg aaaccctgga ggacatcgac 700

 aagaacgggg atgggtttgt ggatcaggat gagtatattg cggatatgtt 750

 ttcccatgag gagaatggcc ctgagccaga ctgggtttta tcagaacggg 800

 agcagtttaa cgaattccgg gatctgaaca aggacgggaa gttagacaaa 850

 gatgagattc gccactggat cctccctcaa gattatgatc acgcacaggc 900

 tgaggccagg catctggtat atgaatcaga caaaaacaag gatgagaagc 950

 taactaaaga ggaaatattg gagaactgga acatgtttgt tggaagccaa 1000

 gctaccaatt acggggaaga tctcacaaaa aatcatgatg agctttgata 1050

 gacactcacc agaatatggc agactgtcat aggcattctg ttattgtctt 1100

 ggattgttgc tacaattgtc taattacagc agttgtgatc ccacaaaaag 1150

 caagtttata cctcagattg gggtataaaa attgtttttc gctcagtatt 1200

 tactggaaaa tggacatcac tagtctttca gtaagatttc tctcaaaaca 1250

 cgtgaaaacc ttggtaaatt gcaattcttt ctggggatat attggtacaa 1300

 catgacttaa aacttttttt tttctattaa aacttaaagg ggaacaaaac 1350

 ttgaaaaagc cctgttcttc agaaggtgag tgggttgagg gaggcagtaa 1400

 tatgaagtga ctgctgtgta ttttaactac cagattttta tatttgccac 1450

 tgttagatag ttggaaaggg gaaattctgt ttaagcgaaa gtggtatcat 1500

 cctaggtaag cttatttcag aacaagtcta atatatcaga ttctttcttt 1550

 tcgactttat actctgagtt attacttact gtaagtggtg tatatgaaac 1600

 ctccatgcat tttccagtat ggatctgcta atatgcacag taaatccatg 1650

 tctttgtttg tttttctatt aagaagcaat caagaaagat aatgtgaaaa 1700

 agaaaggaat ttagaggtag ggaaaagatg aatgtcagac atgtgaagaa 1750

 ctatagtaaa aatgataaac cacctaaata tccttgaacc taccttaaaa 1800

 tgccaatgag gtaggcctga tctttgaata gtggctagga tacaatgcat 1850

 ttcctcagtg atcactgatt agaatgagtt ggtgggatcc ttgggaagcc 1900

 aaacggagcg gggttctgga tcatgtccca tccagtccag tgaatccccg 1950

 acccgcagac ctgccccccc cgcaacagct tataccatgg aatgaggaca 2000

 aggtgatact ctgagctgtg gactgaactg gcagacacaa cctgtacaga 2050

 ttgaaatttc accttgtaag gaggaagtga atgaaataaa ggatccccct 2100

 aagg 2104

<210> 5520
<211> 331
<212> PRT
<213> Homo sapien

<400> 5520
 Met Ala Arg Gly Gly Arg Gly Arg Arg Leu Gly Leu Ala Leu Gly
   1               5                  10                  15

 Leu Leu Leu Ala Leu Val Leu Ala Pro Arg Val Leu Arg Ala Lys
                  20                  25                  30

 Pro Thr Val Arg Lys Glu Arg Val Val Arg Pro Asp Ser Glu Leu
                  35                  40                  45

 Gly Glu Arg Pro Pro Glu Asp Asn Gln Ser Phe Gln Tyr Asp His
                  50                  55                  60

 Glu Ala Phe Leu Gly Lys Glu Asp Ser Lys Thr Phe Asp Gln Leu
                  65                  70                  75

 Thr Pro Asp Glu Ser Lys Glu Arg Leu Gly Lys Ile Val Asp Arg
                  80                  85                  90

 Ile Asp Asn Asp Gly Asp Gly Phe Val Thr Thr Glu Glu Leu Lys
                  95                 100                 105

 Thr Trp Ile Lys Arg Val Gln Lys Arg Tyr Ile Phe Asp Asn Val
                 110                 115                 120

 Ala Lys Val Trp Lys Asp Tyr Asp Arg Asp Lys Asp Asp Lys Ile
                 125                 130                 135

 Ser Trp Glu Glu Tyr Lys Gln Ala Thr Tyr Gly Tyr Tyr Leu Gly
                 140                 145                 150

 Asn Pro Ala Glu Phe His Asp Ser Ser Asp His His Thr Phe Lys
                 155                 160                 165

 Lys Met Leu Pro Arg Asp Glu Arg Arg Phe Lys Ala Ala Asp Leu
                 170                 175                 180

 Asn Gly Asp Leu Thr Ala Thr Arg Glu Glu Phe Thr Ala Phe Leu
                 185                 190                 195

 His Pro Glu Glu Phe Glu His Met Lys Glu Ile Val Val Leu Glu
                 200                 205                 210

 Thr Leu Glu Asp Ile Asp Lys Asn Gly Asp Gly Phe Val Asp Gln
                 215                 220                 225

 Asp Glu Tyr Ile Ala Asp Met Phe Ser His Glu Glu Asn Gly Pro
                 230                 235                 240

 Glu Pro Asp Trp Val Leu Ser Glu Arg Glu Gln Phe Asn Glu Phe
                 245                 250                 255

 Arg Asp Leu Asn Lys Asp Gly Lys Leu Asp Lys Asp Glu Ile Arg
                 260                 265                 270

 His Trp Ile Leu Pro Gln Asp Tyr Asp His Ala Gln Ala Glu Ala
                 275                 280                 285

 Arg His Leu Val Tyr Glu Ser Asp Lys Asn Lys Asp Glu Lys Leu
                 290                 295                 300

 Thr Lys Glu Glu Ile Leu Glu Asn Trp Asn Met Phe Val Gly Ser
                 305                 310                 315

 Gln Ala Thr Asn Tyr Gly Glu Asp Leu Thr Lys Asn His Asp Glu
                 320                 325                 330

 Leu


<210> 5521
<211> 2337
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 61, 2277
<223> Unknown base

<400> 5521
 cggaaggtgt gagccgcaaa cccagcggag ggcgggaaga aggaggaggc 50

 ctctagggtg ntcgggggac tgggggcccc gccggcagag gtccctcggc 100

 ctcctgactg actgactgcg gccgcctccg gccaggacgc tgggagctgc 150

 ctgcgggaag gtgcggggag cggagccatg gcctccggtg cgtataaccc 200

 gtatatagag ataattgaac aacccaggca gaggggaatg cgttttagat 250

 acaaatgtga agggcgatca gcaggcagca ttccagggga gcacagcaca 300

 gacaacaacc gaacataccc ttctatccag attatgaact attatggaaa 350

 aggaaaagtg agaattacat tagtaacaaa gaatgaccca tataaacctc 400

 atcctcatga tttagttgga aaagactgca gagacggcta ctatgaagca 450

 gaatttggac aagaacgcag acctttgttt ttccaaaatt tgggtattcg 500

 atgtgtgaag aaaaaagaag taaaagaagc tattattaca agaataaagg 550

 caggaatcaa tccattcaat gtccctgaaa aacagctgaa tgatattgaa 600

 gattgtgacc tcaatgtggt gagactgtgt tttcaagttt ttctccctga 650

 tgaacatggt aatttgacga ctgctcttcc tcctgttgtc tcgaacccaa 700

 tttatgacaa ccgtgctcca aatactgcag aattaaggat ttgtcgtgta 750

 aacaagaatt gtggaagtgt cagaggagga gatgaaatat ttctactttg 800

 tgacaaagtt cagaaagatg acatagaagt tcgttttgtg ttgaacgatt 850

 gggaagcaaa aggcatcttt tcacaagctg atgtacaccg tcaagtagcc 900

 attgttttca aaactccacc atattgcaaa gctatcacag aacccgtaac 950

 agtaaaaatg cagttgcgga gaccttctga ccaggaagtt agtgaatcta 1000

 tggattttag atatctgcca gatgaaaaag atacttacgg caataaagca 1050

 aagaaacaaa agacaactct gcttttccag aaactgtgcc aggatcacgt 1100

 agaaacaggg tttcgccatg ttgaccagga tggtcttgaa ctcctgacat 1150

 caggtgatcc acccaccttg gcctcccaaa gtgctgggat tacagttaat 1200

 tttcctgaga gaccaagacc tggtctcctc ggttcaattg gagaaggaag 1250

 atacttcaaa aaagaaccaa acttgttttc tcatgatgca gttgtgagag 1300

 aaatgcctac aggggtttca agtcaagcag aatcctacta tccctcacct 1350

 gggcccatct caagtggatt gtcacatcat gcctcaatgg cacctctgcc 1400

 ttcttcaagc tggtcatcag tggcccaccc caccccacgc tcaggcaata 1450

 caaacccact gagtagtttt tcaacaagga cacttccttc taattcgcaa 1500

 ggtatcccac cattcctgag aatacctgtt gggaatgatt taaatgcttc 1550

 taatgcttgc atttacaaca atgccgatga catagtcgga atggaagcgt 1600

 catccatgcc atcagcagat ttatatggta tttctgatcc caacatgctg 1650

 tctaattgtt ctgtgaatat gatgacaacc agcagtgaca gcatgggaga 1700

 gactgataat ccaagacttc tgagcatgaa tcttgaaaac ccctcatgta 1750

 attcagtgtt agacccaaga gacttgagac agctccatca gatgtcctct 1800

 tccagtatgt cagcaggcgc caattccaat actactgttt ttgtttcaca 1850

 atcagatgca tttgagggat ctgacttcag ttgtgcagat aacagcatga 1900

 taaatgagtc gggaccatca aacagtacta atccaaacag tcatggtttt 1950

 gttcaagata gtcagtattc aggtattggc agtatgcaaa atgagcaatt 2000

 gagtgactcc tttccatatg aattttttca agtataactt gcaagattta 2050

 aatcctttta aatcttgata ccacctatat agatgcagca ttttgtattt 2100

 gtctaactgg ggatataata ctatatttat actgtatata taatactgac 2150

 tgagaatata atactgtatt tgagaatata aaaaactttt ttcagggaag 2200

 aagcatacaa ctttggacat agcgaataca aaattggaag ctgtcataaa 2250

 aagacaactc agaggccagg cgcaggngct cacacctgta atcctagcac 2300

 tttgggaggc caaggcgggt ggatcacttg agaccag 2337

<210> 5522
<211> 619
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 61, 2277
<223> Unknown amino acid

<400> 5522
 Met Ala Ser Gly Ala Tyr Asn Pro Tyr Ile Glu Ile Ile Glu Gln
   1               5                  10                  15

 Pro Arg Gln Arg Gly Met Arg Phe Arg Tyr Lys Cys Glu Gly Arg
                  20                  25                  30

 Ser Ala Gly Ser Ile Pro Gly Glu His Ser Thr Asp Asn Asn Arg
                  35                  40                  45

 Thr Tyr Pro Ser Ile Gln Ile Met Asn Tyr Tyr Gly Lys Gly Lys
                  50                  55                  60

 Val Arg Ile Thr Leu Val Thr Lys Asn Asp Pro Tyr Lys Pro His
                  65                  70                  75

 Pro His Asp Leu Val Gly Lys Asp Cys Arg Asp Gly Tyr Tyr Glu
                  80                  85                  90

 Ala Glu Phe Gly Gln Glu Arg Arg Pro Leu Phe Phe Gln Asn Leu
                  95                 100                 105

 Gly Ile Arg Cys Val Lys Lys Lys Glu Val Lys Glu Ala Ile Ile
                 110                 115                 120

 Thr Arg Ile Lys Ala Gly Ile Asn Pro Phe Asn Val Pro Glu Lys
                 125                 130                 135

 Gln Leu Asn Asp Ile Glu Asp Cys Asp Leu Asn Val Val Arg Leu
                 140                 145                 150

 Cys Phe Gln Val Phe Leu Pro Asp Glu His Gly Asn Leu Thr Thr
                 155                 160                 165

 Ala Leu Pro Pro Val Val Ser Asn Pro Ile Tyr Asp Asn Arg Ala
                 170                 175                 180

 Pro Asn Thr Ala Glu Leu Arg Ile Cys Arg Val Asn Lys Asn Cys
                 185                 190                 195

 Gly Ser Val Arg Gly Gly Asp Glu Ile Phe Leu Leu Cys Asp Lys
                 200                 205                 210

 Val Gln Lys Asp Asp Ile Glu Val Arg Phe Val Leu Asn Asp Trp
                 215                 220                 225

 Glu Ala Lys Gly Ile Phe Ser Gln Ala Asp Val His Arg Gln Val
                 230                 235                 240

 Ala Ile Val Phe Lys Thr Pro Pro Tyr Cys Lys Ala Ile Thr Glu
                 245                 250                 255

 Pro Val Thr Val Lys Met Gln Leu Arg Arg Pro Ser Asp Gln Glu
                 260                 265                 270

 Val Ser Glu Ser Met Asp Phe Arg Tyr Leu Pro Asp Glu Lys Asp
                 275                 280                 285

 Thr Tyr Gly Asn Lys Ala Lys Lys Gln Lys Thr Thr Leu Leu Phe
                 290                 295                 300

 Gln Lys Leu Cys Gln Asp His Val Glu Thr Gly Phe Arg His Val
                 305                 310                 315

 Asp Gln Asp Gly Leu Glu Leu Leu Thr Ser Gly Asp Pro Pro Thr
                 320                 325                 330

 Leu Ala Ser Gln Ser Ala Gly Ile Thr Val Asn Phe Pro Glu Arg
                 335                 340                 345

 Pro Arg Pro Gly Leu Leu Gly Ser Ile Gly Glu Gly Arg Tyr Phe
                 350                 355                 360

 Lys Lys Glu Pro Asn Leu Phe Ser His Asp Ala Val Val Arg Glu
                 365                 370                 375

 Met Pro Thr Gly Val Ser Ser Gln Ala Glu Ser Tyr Tyr Pro Ser
                 380                 385                 390

 Pro Gly Pro Ile Ser Ser Gly Leu Ser His His Ala Ser Met Ala
                 395                 400                 405

 Pro Leu Pro Ser Ser Ser Trp Ser Ser Val Ala His Pro Thr Pro
                 410                 415                 420

 Arg Ser Gly Asn Thr Asn Pro Leu Ser Ser Phe Ser Thr Arg Thr
                 425                 430                 435

 Leu Pro Ser Asn Ser Gln Gly Ile Pro Pro Phe Leu Arg Ile Pro
                 440                 445                 450

 Val Gly Asn Asp Leu Asn Ala Ser Asn Ala Cys Ile Tyr Asn Asn
                 455                 460                 465

 Ala Asp Asp Ile Val Gly Met Glu Ala Ser Ser Met Pro Ser Ala
                 470                 475                 480

 Asp Leu Tyr Gly Ile Ser Asp Pro Asn Met Leu Ser Asn Cys Ser
                 485                 490                 495

 Val Asn Met Met Thr Thr Ser Ser Asp Ser Met Gly Glu Thr Asp
                 500                 505                 510

 Asn Pro Arg Leu Leu Ser Met Asn Leu Glu Asn Pro Ser Cys Asn
                 515                 520                 525

 Ser Val Leu Asp Pro Arg Asp Leu Arg Gln Leu His Gln Met Ser
                 530                 535                 540

 Ser Ser Ser Met Ser Ala Gly Ala Asn Ser Asn Thr Thr Val Phe
                 545                 550                 555

 Val Ser Gln Ser Asp Ala Phe Glu Gly Ser Asp Phe Ser Cys Ala
                 560                 565                 570

 Asp Asn Ser Met Ile Asn Glu Ser Gly Pro Ser Asn Ser Thr Asn
                 575                 580                 585

 Pro Asn Ser His Gly Phe Val Gln Asp Ser Gln Tyr Ser Gly Ile
                 590                 595                 600

 Gly Ser Met Gln Asn Glu Gln Leu Ser Asp Ser Phe Pro Tyr Glu
                 605                 610                 615

 Phe Phe Gln Val


<210> 5523
<211> 542
<212> DNA
<213> Homo sapien

<400> 5523
 acagtggtga gctcttagct tcaccaggct catcaaagct gctccaggaa 50

 ggcccaagcc agaccagaag acatgcagat catcaccaca gccctggtgt 100

 gcttgctgct agctgggatg tggccggaag atgtggacag caagagcatg 150

 caggtaccct tctccagatg ttgcttctca tttgcggagc aagagattcc 200

 cctgagggca atcctgtgtt acagaaatac cagctccatc tgctccaatg 250

 agggcttaat attcaagctg aagagaggca aagaggcctg cgccttggac 300

 acagttggat gggttcagag gcacagaaaa atgctgaggc actgcccgtc 350

 aaaaagaaaa tgagcagatt tctttccatt gtgggctctg gaaaccacat 400

 ggcttcacct gtccccgaaa ctaccagccc tacaccattc cttctgccct 450

 gcttttgcta ggtcacagag gatctgcttg gtcttgataa gctatgttgt 500

 tgcactttaa acatttaaat tatacaatca tcaaccccca ac 542

<210> 5524
<211> 96
<212> PRT
<213> Homo sapien

<400> 5524
 Met Gln Ile Ile Thr Thr Ala Leu Val Cys Leu Leu Leu Ala Gly
   1               5                  10                  15

 Met Trp Pro Glu Asp Val Asp Ser Lys Ser Met Gln Val Pro Phe
                  20                  25                  30

 Ser Arg Cys Cys Phe Ser Phe Ala Glu Gln Glu Ile Pro Leu Arg
                  35                  40                  45

 Ala Ile Leu Cys Tyr Arg Asn Thr Ser Ser Ile Cys Ser Asn Glu
                  50                  55                  60

 Gly Leu Ile Phe Lys Leu Lys Arg Gly Lys Glu Ala Cys Ala Leu
                  65                  70                  75

 Asp Thr Val Gly Trp Val Gln Arg His Arg Lys Met Leu Arg His
                  80                  85                  90

 Cys Pro Ser Lys Arg Lys
                  95

<210> 5525
<211> 776
<212> DNA
<213> Homo sapien

<400> 5525
 aaggacacgg gcagcagaca gtggtcagtc ctttcttggc tctgctgaca 50

 ctcgagccca cattccgtca cctgctcaga atcatgcagg tctccactgc 100

 tgcccttgct gtcctcctct gcaccatggc tctctgcaac cagttctctg 150

 catcacttgc tgctgacacg ccgaccgcct gctgcttcag ctacacctcc 200

 cggcagattc cacagaattt catagctgac tactttgaga cgagcagcca 250

 gtgctccaag cccggtgtca tcttcctaac caagcgaagc cggcaggtct 300

 gtgctgaccc cagtgaggag tgggtccaga aatatgtcag cgacctagag 350

 ctgagtgcct gaggggtcca gaagcttcga ggcccagcga cctcggtggg 400

 ccagtgggga ggagcaggag cctgagcctt gggaaacatg cgtgtgacct 450

 ccacagctac ctcttctatg gactggttgt tgccaaacag ccacactgtg 500

 ggactcttct taacttaaat tttaatttat ttatactatt tagtttttgt 550

 aatttatttt cgatttcaca gtgtgtttgt gattgtttgc tctgagagtt 600

 cccctgtccc ctcccccttc cctcacaccg cgtctggtga caaccgagtg 650

 gctgtcatca gcctgtgtag gcagtcatgg caccaaagcc accagactga 700

 caaatgtgta tcggatgctt ttgttcaggg ctgtgatcgg cctggggaaa 750

 taataaagca cgctctttta aaaggt 776

<210> 5526
<211> 92
<212> PRT
<213> Homo sapien

<400> 5526
 Met Gln Val Ser Thr Ala Ala Leu Ala Val Leu Leu Cys Thr Met
   1               5                  10                  15

 Ala Leu Cys Asn Gln Phe Ser Ala Ser Leu Ala Ala Asp Thr Pro
                  20                  25                  30

 Thr Ala Cys Cys Phe Ser Tyr Thr Ser Arg Gln Ile Pro Gln Asn
                  35                  40                  45

 Phe Ile Ala Asp Tyr Phe Glu Thr Ser Ser Gln Cys Ser Lys Pro
                  50                  55                  60

 Gly Val Ile Phe Leu Thr Lys Arg Ser Arg Gln Val Cys Ala Asp
                  65                  70                  75

 Pro Ser Glu Glu Trp Val Gln Lys Tyr Val Ser Asp Leu Glu Leu
                  80                  85                  90

 Ser Ala


<210> 5527
<211> 696
<212> DNA
<213> Homo sapien

<400> 5527
 ttcccccccc cccccccccc ccccgcccga gcacaggaca cagctgggtt 50

 ctgaagcttc tgagttctgc agcctcacct ctgagaaaac ctcttttcca 100

 ccaataccat gaagctctgc gtgactgtcc tgtctctcct catgctagta 150

 gctgccttct gctctccagc gctctcagca ccaatgggct cagaccctcc 200

 caccgcctgc tgcttttctt acaccgcgag gaagcttcct cgcaactttg 250

 tggtagatta ctatgagacc agcagcctct gctcccagcc agctgtggta 300

 ttccaaacca aaagaagcaa gcaagtctgt gctgatccca gtgaatcctg 350

 ggtccaggag tacgtgtatg acctggaact gaactgagct gctcagagac 400

 aggaagtctt cagggaaggt cacctgagcc cggatgcttc tccatgagac 450

 acatctcctc catactcagg actcctctcc gcagttcctg tcccttctct 500

 taatttaatc ttttttatgt gccgtgttat tgtattaggt gtcatttcca 550

 ttatttatat tagtttagcc aaaggataag tgtcctatgg ggatggtcca 600

 ctgtcactgt ttctctgctg ttgcaaatac atggataaca catttgattc 650

 tgtgtgtttt ccataataaa actttaaaat aaaatgcaga cagtta 696

<210> 5528
<211> 92
<212> PRT
<213> Homo sapien

<400> 5528
 Met Lys Leu Cys Val Thr Val Leu Ser Leu Leu Met Leu Val Ala
   1               5                  10                  15

 Ala Phe Cys Ser Pro Ala Leu Ser Ala Pro Met Gly Ser Asp Pro
                  20                  25                  30

 Pro Thr Ala Cys Cys Phe Ser Tyr Thr Ala Arg Lys Leu Pro Arg
                  35                  40                  45

 Asn Phe Val Val Asp Tyr Tyr Glu Thr Ser Ser Leu Cys Ser Gln
                  50                  55                  60

 Pro Ala Val Val Phe Gln Thr Lys Arg Ser Lys Gln Val Cys Ala
                  65                  70                  75

 Asp Pro Ser Glu Ser Trp Val Gln Glu Tyr Val Tyr Asp Leu Glu
                  80                  85                  90

 Leu Asn


<210> 5529
<211> 2577
<212> DNA
<213> Homo sapien

<400> 5529
 cacatgtcgg cgcaggcggc caaagtcagt aaaaaggagc tcaactccaa 50

 ccacgacggg gccgacgaga cctcagaaaa agaacagcaa gaagcgattg 100

 aacacattga tgaagtacaa aatgaaatag acagacttaa tgaacaagcc 150

 agtgaggaga ttttgaaagt agaacagaaa tataacaaac tccgccaacc 200

 attttttcag aagaggtcag aattgatcgc caaaatccca aatttttggg 250

 taacaacatt tgtcaaccat ccacaagtgt ctgcactgct tggggaggaa 300

 gatgaagagg cactgcatta tttgaccaga gttgaagtga cagaatttga 350

 agatattaaa tcaggttaca gaatagattt ttattttgat gaaaatcctt 400

 actttgaaaa taaagttctc tccaaagaat ttcatctgaa tgagagtggt 450

 gatccatctt cgaagtccac cgaaatcaaa tggaaatctg gaaaggattt 500

 gacgaaacgt tcgagtcaaa cgcagaataa agccagcagg aagaggcagc 550

 atgaggaacc agagagcttc tttacctggt ttactgacca ttctgatgca 600

 ggtgctgatg agttaggaga ggtcatcaaa gatgatattt ggccaaaccc 650

 attacagtac tacttggttc ccgatatgga tgatgaagaa ggagaaggag 700

 aagaagatga tgatgatgat gaagaggagg aaggattaga agatattgac 750

 gaagaagggg atgaggatga aggtgaagaa gatgaagatg atgatgaagg 800

 ggaggaagga gaggaggatg aaggagaaga tgactaaata gaacactgat 850

 ggattccaac cttccttttt ttaaattttc tccagtccct gggagcaagt 900

 tgcagtcttt tttttttttt tttttttttt ccctcttgtg ctcagtcgcc 950

 ctgttcttga ggtctctttt ctctactcca tggttctcaa tttatttggg 1000

 gggaaatacc ttgagcagaa tacaatggga aaagagtctc tacccctttc 1050

 tgttcgaagt tcatttttat cccttcctgt ctgaacaaaa actgtatgga 1100

 atcaacacca ccgagctctg tgggaaaaaa gaaaaacctg ctccctttgc 1150

 tctgctggaa gctggagggt gctaggcccc tgtgtagtag tgtatagaat 1200

 tctagctttt ttcctccttt ctctgtatat tgggctcaga gagtacactg 1250

 tgtctctatg tgaatatgga cagttagcat ttaccaacat gtatctgtct 1300

 actttctctt gtttaaaaaa agaaaaaaaa acttaaaaaa atggggttat 1350

 agaaggtcag caaaggggtg gggtttgaga tgtttgggtg ggttagtggg 1400

 cattttgaca acatggcttc tcctttggca tgtttaattg tgatatttga 1450

 cagacatcct tgcagtttaa gatgacactt ttaaaataaa ttctctccta 1500

 atgatgactt gagccctgcc actcaatggg agaatcagca gaacctgtag 1550

 gatcttattt ggaattgaca ttctctattg taattttgtt cctgtttatt 1600

 tttgggtttc tttttgtttc actggaaagg aaagatgatg ctcagtttta 1650

 aacgttaaaa gtgtacaagt tgctttgtta caataaaact aaatgtgtac 1700

 acaaaggatt tgatgctttt ctctcagcat aggtatgctt actatgacct 1750

 tccaagtttg acttgtataa catcactgtc aaactttgtc accctaactt 1800

 cgtatttttt gatacgcact tttgcaggat gacctcaggg ctatgtggat 1850

 tgagtaatgg gatttgaatc aatgtattaa tatctccata gctgggaaac 1900

 gtgggttcaa tttgccattg gtttctgaaa agtattcaca tcatttggga 1950

 taccagatag ctcaatactc tctgagtaca ttgtgccctt gatttttatc 2000

 tccaagtggc agtttttaaa attggccttt tacctggata taaattaatt 2050

 gtgcctgcca ccaccatcca acagacctgg tgctctaatg ccaagttata 2100

 cacgggacag ttgctggcat gtcttcattg gctctctaaa atgtggccaa 2150

 gaagataggc tctcagtaag aagtctgatg gtgagcagta actgtccctg 2200

 ctttctggta taaagctctc aaatgtgacc atgtgaatct gggtgggata 2250

 atggactcag ctctgtctgc tcaatgccat tgtgcagaga agcaccctaa 2300

 tgcataagct ttttaatgct gtaaaatata gtcgctgaaa ttaaatgcca 2350

 ctttttcaga ggtgaattaa tggacagtct ggtgaacttc aaaagctttt 2400

 tgatgtataa aacttgataa atggaactat tccatcaata ggcaaaagtg 2450

 taacaaccta tctagatgga tagtatgtaa tttctgcaca ggtctctgtt 2500

 tagtaaatac atcactgtat accgatcagg aatcttgctc caataaagga 2550

 acataaagat ttaaaaaaaa aaaaaaa 2577

<210> 5530
<211> 277
<212> PRT
<213> Homo sapien

<400> 5530
 Met Ser Ala Gln Ala Ala Lys Val Ser Lys Lys Glu Leu Asn Ser
   1               5                  10                  15

 Asn His Asp Gly Ala Asp Glu Thr Ser Glu Lys Glu Gln Gln Glu
                  20                  25                  30

 Ala Ile Glu His Ile Asp Glu Val Gln Asn Glu Ile Asp Arg Leu
                  35                  40                  45

 Asn Glu Gln Ala Ser Glu Glu Ile Leu Lys Val Glu Gln Lys Tyr
                  50                  55                  60

 Asn Lys Leu Arg Gln Pro Phe Phe Gln Lys Arg Ser Glu Leu Ile
                  65                  70                  75

 Ala Lys Ile Pro Asn Phe Trp Val Thr Thr Phe Val Asn His Pro
                  80                  85                  90

 Gln Val Ser Ala Leu Leu Gly Glu Glu Asp Glu Glu Ala Leu His
                  95                 100                 105

 Tyr Leu Thr Arg Val Glu Val Thr Glu Phe Glu Asp Ile Lys Ser
                 110                 115                 120

 Gly Tyr Arg Ile Asp Phe Tyr Phe Asp Glu Asn Pro Tyr Phe Glu
                 125                 130                 135

 Asn Lys Val Leu Ser Lys Glu Phe His Leu Asn Glu Ser Gly Asp
                 140                 145                 150

 Pro Ser Ser Lys Ser Thr Glu Ile Lys Trp Lys Ser Gly Lys Asp
                 155                 160                 165

 Leu Thr Lys Arg Ser Ser Gln Thr Gln Asn Lys Ala Ser Arg Lys
                 170                 175                 180

 Arg Gln His Glu Glu Pro Glu Ser Phe Phe Thr Trp Phe Thr Asp
                 185                 190                 195

 His Ser Asp Ala Gly Ala Asp Glu Leu Gly Glu Val Ile Lys Asp
                 200                 205                 210

 Asp Ile Trp Pro Asn Pro Leu Gln Tyr Tyr Leu Val Pro Asp Met
                 215                 220                 225

 Asp Asp Glu Glu Gly Glu Gly Glu Glu Asp Asp Asp Asp Asp Glu
                 230                 235                 240

 Glu Glu Glu Gly Leu Glu Asp Ile Asp Glu Glu Gly Asp Glu Asp
                 245                 250                 255

 Glu Gly Glu Glu Asp Glu Asp Asp Asp Glu Gly Glu Glu Gly Glu
                 260                 265                 270

 Glu Asp Glu Gly Glu Asp Asp
                 275

<210> 5531
<211> 1789
<212> DNA
<213> Homo sapien

<400> 5531
 ggttcaggaa cctgctggtt ctgatacata aatcagacag cctctgctgc 50

 atgacacgaa gcttgcttct gcctggcatc tgtgagcagc tgccaggctc 100

 cggccaggat cccttccttc tcctcattgg ctgatggatc ccaaggggct 150

 cctctccttg accttcgtgc tgtttctctc cctggctttt ggggcaagct 200

 acggaacagg tgggcgcatg atgaactgcc caaagattct ccggcagttg 250

 ggaagcaaag tgctgctgcc cctgacatat gaaaggataa ataagagcat 300

 gaacaaaagc atccacattg tcgtcacaat ggcaaaatca ctggagaaca 350

 gtgtcgagaa caaaatagtg tctcttgatc catccgaagc aggccctcca 400

 cgttatctag gagatcgcta caagttttat ctggagaatc tcaccctggg 450

 gatacgggaa agcaggaagg aggatgaggg atggtacctt atgaccctgg 500

 agaaaaatgt ttcagttcag cgcttttgcc tgcagttgag gctttatgag 550

 caggtctcca ctccagaaat taaagtttta aacaagaccc aggagaacgg 600

 gacctgcacc ttgatactgg gctgcacagt ggagaagggg gaccatgtgg 650

 cttacagctg gagtgaaaag gcgggcaccc acccactgaa cccagccaac 700

 agctcccacc tcctgtccct caccctcggc ccccagcatg ctgacaatat 750

 ctacatctgc accgtgagca accctatcag caacaattcc cagaccttca 800

 gcccgtggcc cggatgcagg acagacccct cagaaacaaa accatgggca 850

 gtgtatgctg ggctgttagg gggtgtcatc atgattctca tcatggtggt 900

 aatactacag ttgagaagaa gaggtaaaac gaaccattac cagacaacag 950

 tggaaaaaaa aagccttacg atctatgccc aagtccagaa accaggtcct 1000

 cttcagaaga aacttgactc cttcccagct caggaccctt gcaccaccat 1050

 atatgttgct gccacagagc ctgtcccaga gtctgtccag gaaacaaatt 1100

 ccatcacagt ctatgctagt gtgacacttc cagagagctg acaccagaga 1150

 ccaacaaagg gactttctga aggaaaatgg aaaaaccaaa atgaacactg 1200

 aacttggcca caggcccaag tttcctctgg cagacatgct gcacgtctgt 1250

 acccttctca gatcaactcc ctggtgatgt ttcttccaca tacatctgtg 1300

 aaatgaacaa ggaagtgagg cttcccaaga atttagcttg ctgtgcagtg 1350

 gctgcaggcg cagaacagag cgttacttga taacagcgtt ccatctttgt 1400

 gttgtagcag atgaaatgga cagtaatgtg agttcagact ttgggcatct 1450

 tgctcttggc tggaactgat aataaaaatc agactgaaag ccaggacatc 1500

 tgagtaccta tctcacacac tgaccaccag tcacaaagtc tggaaaagtt 1550

 tacattttgg ctatctttac tttgttctgg gagctgatca tgataacctg 1600

 cagacctgat caagcctctg tgcctcagtt tctctctcag gataaagagt 1650

 gaatagaggc cgaagggtga atttcttatt atacataaaa cactctgata 1700

 ttattgtata aaggaagcta agaatattat tttatttgca aaacccagaa 1750

 gctaaaaagt caataaacag aaagaatgat tttgagaaa 1789

<210> 5532
<211> 335
<212> PRT
<213> Homo sapien

<400> 5532
 Met Asp Pro Lys Gly Leu Leu Ser Leu Thr Phe Val Leu Phe Leu
   1               5                  10                  15

 Ser Leu Ala Phe Gly Ala Ser Tyr Gly Thr Gly Gly Arg Met Met
                  20                  25                  30

 Asn Cys Pro Lys Ile Leu Arg Gln Leu Gly Ser Lys Val Leu Leu
                  35                  40                  45

 Pro Leu Thr Tyr Glu Arg Ile Asn Lys Ser Met Asn Lys Ser Ile
                  50                  55                  60

 His Ile Val Val Thr Met Ala Lys Ser Leu Glu Asn Ser Val Glu
                  65                  70                  75

 Asn Lys Ile Val Ser Leu Asp Pro Ser Glu Ala Gly Pro Pro Arg
                  80                  85                  90

 Tyr Leu Gly Asp Arg Tyr Lys Phe Tyr Leu Glu Asn Leu Thr Leu
                  95                 100                 105

 Gly Ile Arg Glu Ser Arg Lys Glu Asp Glu Gly Trp Tyr Leu Met
                 110                 115                 120

 Thr Leu Glu Lys Asn Val Ser Val Gln Arg Phe Cys Leu Gln Leu
                 125                 130                 135

 Arg Leu Tyr Glu Gln Val Ser Thr Pro Glu Ile Lys Val Leu Asn
                 140                 145                 150

 Lys Thr Gln Glu Asn Gly Thr Cys Thr Leu Ile Leu Gly Cys Thr
                 155                 160                 165

 Val Glu Lys Gly Asp His Val Ala Tyr Ser Trp Ser Glu Lys Ala
                 170                 175                 180

 Gly Thr His Pro Leu Asn Pro Ala Asn Ser Ser His Leu Leu Ser
                 185                 190                 195

 Leu Thr Leu Gly Pro Gln His Ala Asp Asn Ile Tyr Ile Cys Thr
                 200                 205                 210

 Val Ser Asn Pro Ile Ser Asn Asn Ser Gln Thr Phe Ser Pro Trp
                 215                 220                 225

 Pro Gly Cys Arg Thr Asp Pro Ser Glu Thr Lys Pro Trp Ala Val
                 230                 235                 240

 Tyr Ala Gly Leu Leu Gly Gly Val Ile Met Ile Leu Ile Met Val
                 245                 250                 255

 Val Ile Leu Gln Leu Arg Arg Arg Gly Lys Thr Asn His Tyr Gln
                 260                 265                 270

 Thr Thr Val Glu Lys Lys Ser Leu Thr Ile Tyr Ala Gln Val Gln
                 275                 280                 285

 Lys Pro Gly Pro Leu Gln Lys Lys Leu Asp Ser Phe Pro Ala Gln
                 290                 295                 300

 Asp Pro Cys Thr Thr Ile Tyr Val Ala Ala Thr Glu Pro Val Pro
                 305                 310                 315

 Glu Ser Val Gln Glu Thr Asn Ser Ile Thr Val Tyr Ala Ser Val
                 320                 325                 330

 Thr Leu Pro Glu Ser
                 335

<210> 5533
<211> 5681
<212> DNA
<213> Homo sapien

<400> 5533
 cgccgcggtg ctgaggggga ggggagccgg cgagcgcgcg cgcagcgggg 50

 gcgcgggtgg cgcgcgtgtg tgtgaagggg gggcggtggc cgaggcgggc 100

 gggcgcgcgc gcgaggcttc ccctcgtttg gcggcggcgg cggcttcttt 150

 gtttcgtgaa gagaagcgag acgcccattc tgcccccggc cccgcgcgga 200

 ggggcggggg aggcgccggg aagtcgacgg cgccggcggc tcctgcagga 250

 ggccactgtc tgcagctccc gtgaagatgt ccactccaga cccacccctg 300

 ggcggaactc ctcggccagg tccttccccg ggccctggcc cttcccctgg 350

 agccatgctg ggccctagcc cgggtccctc gccgggctcc gcccacagca 400

 tgatggggcc cagcccaggg ccgccctcag caggacaccc catccccacc 450

 caggggcctg gagggtaccc tcaggacaac atgcaccaga tgcacaagcc 500

 catggagtcc atgcatgaga agggcatgtc ggacgacccg cgctacaacc 550

 agatgaaagg aatggggatg cggtcagggg gccatgctgg gatggggccc 600

 ccgcccagcc ccatggacca gcactcccaa ggttacccct cgcccctggg 650

 tggctctgag catgcctcta gtccagttcc agccagtggc ccgtcttcgg 700

 ggccccagat gtcttccggg ccaggaggtg ccccgctgga tggtgctgac 750

 ccccaggcct tggggcagca gaaccggggc ccaaccccat ttaaccagaa 800

 ccagctgcac cagctcagag ctcagatcat ggcctacaag atgctggcca 850

 gggggcagcc cctccccgac cacctgcaga tggcggtgca gggcaagcgg 900

 ccgatgcccg ggatgcagca gcagatgcca acgctacctc caccctcggt 950

 gtccgcaaca ggacccggcc ctggccctgg ccctggcccc ggcccgggtc 1000

 ccggcccggc acctccaaat tacagcaggc ctcatggtat gggagggccc 1050

 aacatgcctc ccccaggacc ctcgggcgtg ccccccggga tgccaggcca 1100

 gcctcctgga gggcctccca agccctggcc tgaaggaccc atggcgaatg 1150

 ctgctgcccc cacgagcacc cctcagaagc tgattccccc gcagccaacg 1200

 ggccgccctt cccccgcgcc ccctgccgtc ccacccgccg cctcgcccgt 1250

 gatgccaccg cagacccagt cccccgggca gccggcccag cccgcgccca 1300

 tggtgccact gcaccagaag cagagccgca tcacccccat ccagaagccg 1350

 cggggcctcg accctgtgga gatcctgcag gagcgcgagt acaggctgca 1400

 ggctcgcatc gcacaccgaa ttcaggaact tgaaaacctt cccgggtccc 1450

 tggccgggga tttgcgaacc aaagcgacca ttgagctcaa ggccctcagg 1500

 ctgctgaact tccagaggca gctgcgccag gaggtggtgg tgtgcatgcg 1550

 gagggacaca gcgctggaga cagccctcaa tgctaaggcc tacaagcgca 1600

 gcaagcgcca gtccctgcgc gaggcccgca tcactgagaa gctggagaag 1650

 cagcagaaga tcgagcagga gcgcaagcgc cggcagaagc accaggaata 1700

 cctcaatagc attctccagc atgccaagga tttcaaggaa tatcacagat 1750

 ccgtcacagg caaaatccag aagctgacca aggcagtggc cacgtaccat 1800

 gccaacacgg agcgggagca gaagaaagag aacgagcgga tcgagaagga 1850

 gcgcatgcgg aggctcatgg ctgaagatga ggaggggtac cgcaagctca 1900

 tcgaccagaa gaaggacaag cgcctggcct acctcttgca gcagacagac 1950

 gagtacgtgg ctaacctcac ggagctggtg cggcagcaca aggctgccca 2000

 ggtcgccaag gagaaaaaga agaaaaagaa aaagaagaag gcagaaaatg 2050

 cagaaggaca gacgcctgcc attgggccgg atggcgagcc tctggacgag 2100

 accagccaga tgagcgacct cccggtgaag gtgatccacg tggagagtgg 2150

 gaagatcctc acaggcacag atgcccccaa agccgggcag ctggaggcct 2200

 ggctcgagat gaacccgggg tatgaagtag ctccgaggtc tgatagtgaa 2250

 gaaagtggct cagaagaaga ggaagaggag gaggaggaag agcagccgca 2300

 ggcagcacag cctcccaccc tgcccgtgga ggagaagaag aagattccag 2350

 atccagacag cgatgacgtc tctgaggtgg acgcgcggca catcattgag 2400

 aatgccaagc aagatgtcga tgatgaatat ggcgtgtccc aggcccttgc 2450

 acgtggcctg cagtcctact atgccgtggc ccatgctgtc actgagagag 2500

 tggacaagca gtcagcgctt atggtcaatg gtgtcctcaa acagtaccag 2550

 atcaaaggtt tggagtggct ggtgtccctg tacaacaaca acctgaacgg 2600

 catcctggcc gacgagatgg gcctggggaa gaccatccag accatcgcgc 2650

 tcatcacgta cctcatggag cacaaacgca tcaatgggcc cttcctcatc 2700

 atcgtgcctc tctcaacgct gtccaactgg gcgtacgagt ttgacaagtg 2750

 ggccccctcc gtggtgaagg tgtcttacaa gggatcccca gcagcaagac 2800

 gggcctttgt cccccagctc cggagtggga agttcaacgt cttgctgacg 2850

 acgtacgagt acatcatcaa agacaagcac atcctcgcca agatccgttg 2900

 gaagtacatg attgtggacg aaggtcaccg catgaagaac caccactgca 2950

 agctgacgca ggtgctcaac acgcactatg tggcaccccg ccgcctgctg 3000

 ctgacgggca caccgctgca gaacaagctt cccgagctct gggcgctgct 3050

 caacttcctg ctgcccacca tcttcaagag ctgcagcacc ttcgagcagt 3100

 ggtttaacgc accctttgcc atgaccgggg aaaaggtgga cctgaatgag 3150

 gaggaaacca ttctcatcat ccggcgtctc cacaaagtgc tgcggccctt 3200

 cttgctccga cgactcaaga aggaagtcga ggcccagttg cccgaaaagg 3250

 tggagtacgt catcaagtgc gacatgtctg cgctgcagcg agtgctctac 3300

 cgccacatgc aggccaaggg cgtgctgctg actgatggct ccgagaagga 3350

 caagaagggc aaaggcggca ccaagaccct gatgaacacc atcatgcagc 3400

 tgcggaagat ctgcaaccac ccctacatgt tccagcacat cgaggagtcc 3450

 ttttccgagc acttggggtt cactggcggc attgtccaag ggctggacct 3500

 gtaccgagcc tcgggtaaat ttgagcttct tgatagaatt cttcccaaac 3550

 tccgagcaac caaccacaaa gtgctgctgt tctgccaaat gacctccctc 3600

 atgaccatca tggaagatta ctttgcgtat cgcggcttta aatacctcag 3650

 gcttgatgga accacgaagg cggaggaccg gggcatgctg ctgaaaacct 3700

 tcaacgagcc cggctctgag tacttcatct tcctgctcag cacccgggct 3750

 ggggggctcg gcctgaacct ccagtcggca gacactgtga tcatttttga 3800

 cagcgactgg aatcctcacc aggacctgca agcgcaggac cgagcccacc 3850

 gcatcgggca gcagaacgag gtgcgtgtgc tccgcctctg caccgtcaac 3900

 agcgtggagg agaagatcct agctgcagcc aagtacaagc tcaacgtgga 3950

 ccagaaggtg atccaggccg gcatgttcga ccagaagtcc tccagccatg 4000

 agcggcgcgc cttcctgcag gccatcctgg agcacgagga gcaggatgag 4050

 agcagacact gcagcacggg cagcggcagt gccagcttcg cccacactgc 4100

 ccctccgcca gcgggcgtca accccgactt ggaggagcca cctctaaagg 4150

 aggaagacga ggtgcccgac gacgagaccg tcaaccagat gatcgcccgg 4200

 cacgaggagg agtttgatct gttcatgcgc atggacctgg accgcaggcg 4250

 cgaggaggcc cgcaacccca agcggaagcc gcgcctcatg gaggaggacg 4300

 agctcccctc gtggatcatc aaggacgacg cggaggtgga gcggctgacc 4350

 tgtgaggagg aggaggagaa gatgttcggc cgtggctccc gccaccgcaa 4400

 ggaggtggac tacagcgact cactgacgga gaagcagtgg ctcaaggcca 4450

 tcgaggaggg cacgctggag gagatcgaag aggaggtccg gcagaagaaa 4500

 tcatcacgga agcgcaagcg agacagcgac gccggctcct ccaccccgac 4550

 caccagcacc cgcagccgcg acaaggacga cgagagcaag aagcagaaga 4600

 agcgcgggcg gccgcctgcc gagaaactct cccctaaccc acccaacctc 4650

 accaagaaga tgaagaagat tgtggatgcc gtgatcaagt acaaggacag 4700

 cagcagtgga cgtcagctca gcgaggtctt catccagctg ccctcgcgaa 4750

 aggagctgcc cgagtactac gagctcatcc gcaagcccgt ggacttcaag 4800

 aagataaagg agcgcattcg caaccacaag taccgcagcc tcaacgacct 4850

 agagaaggac gtcatgctcc tgtgccagaa cgcacagacc ttcaacctgg 4900

 agggctccct gatctatgaa gactccatcg tcttgcagtc ggtcttcacc 4950

 agcgtgcggc agaaaatcga gaaggaggat gacagtgaag gcgaggagag 5000

 tgaggaggag gaagagggcg aggaggaagg ctccgaatcc gaatctcggt 5050

 ccgtcaaagt gaagatcaag cttggccgga aggagaaggc acaggaccgg 5100

 ctgaagggcg gccggcggcg gccgagccga gggtcccgag ccaagccggt 5150

 cgtgagtgac gatgacagtg aggaggaaca agaggaggac cgctcaggaa 5200

 gtggcagcga agaagactga gccccgacat tccagtctcg accccgagcc 5250

 cctcgttcca gagctgagat ggcataggcc ttagcagtaa cgggtagcag 5300

 cagatgtagt ttcagacttg gagtaaaact gtataaacaa aagaatcttc 5350

 catatttata cagcagagaa gctgtaggac tgtttgtgac tggccctgtc 5400

 ctggcatcag tagcatctgt aacagcatta actgtcttaa agagagagag 5450

 agagaattcc gaattgggga acacacgata cctgtttttc ttttccgttg 5500

 ctggcagtac tgttgcgccg cagtttggag tcactgtagt taagtgtgga 5550

 tgcatgtgcg tcaccgtcca ctcctcctac tgtattttat tggacaggtc 5600

 agactcgccg ggggcccggc gagggtatgt cagtgtcact ggatgtcaaa 5650

 cagtaataaa ttaaaccaac aacaaaacgc a 5681

<210> 5534
<211> 1647
<212> PRT
<213> Homo sapien

<400> 5534
 Met Ser Thr Pro Asp Pro Pro Leu Gly Gly Thr Pro Arg Pro Gly
   1               5                  10                  15

 Pro Ser Pro Gly Pro Gly Pro Ser Pro Gly Ala Met Leu Gly Pro
                  20                  25                  30

 Ser Pro Gly Pro Ser Pro Gly Ser Ala His Ser Met Met Gly Pro
                  35                  40                  45

 Ser Pro Gly Pro Pro Ser Ala Gly His Pro Ile Pro Thr Gln Gly
                  50                  55                  60

 Pro Gly Gly Tyr Pro Gln Asp Asn Met His Gln Met His Lys Pro
                  65                  70                  75

 Met Glu Ser Met His Glu Lys Gly Met Ser Asp Asp Pro Arg Tyr
                  80                  85                  90

 Asn Gln Met Lys Gly Met Gly Met Arg Ser Gly Gly His Ala Gly
                  95                 100                 105

 Met Gly Pro Pro Pro Ser Pro Met Asp Gln His Ser Gln Gly Tyr
                 110                 115                 120

 Pro Ser Pro Leu Gly Gly Ser Glu His Ala Ser Ser Pro Val Pro
                 125                 130                 135

 Ala Ser Gly Pro Ser Ser Gly Pro Gln Met Ser Ser Gly Pro Gly
                 140                 145                 150

 Gly Ala Pro Leu Asp Gly Ala Asp Pro Gln Ala Leu Gly Gln Gln
                 155                 160                 165

 Asn Arg Gly Pro Thr Pro Phe Asn Gln Asn Gln Leu His Gln Leu
                 170                 175                 180

 Arg Ala Gln Ile Met Ala Tyr Lys Met Leu Ala Arg Gly Gln Pro
                 185                 190                 195

 Leu Pro Asp His Leu Gln Met Ala Val Gln Gly Lys Arg Pro Met
                 200                 205                 210

 Pro Gly Met Gln Gln Gln Met Pro Thr Leu Pro Pro Pro Ser Val
                 215                 220                 225

 Ser Ala Thr Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro
                 230                 235                 240

 Gly Pro Gly Pro Ala Pro Pro Asn Tyr Ser Arg Pro His Gly Met
                 245                 250                 255

 Gly Gly Pro Asn Met Pro Pro Pro Gly Pro Ser Gly Val Pro Pro
                 260                 265                 270

 Gly Met Pro Gly Gln Pro Pro Gly Gly Pro Pro Lys Pro Trp Pro
                 275                 280                 285

 Glu Gly Pro Met Ala Asn Ala Ala Ala Pro Thr Ser Thr Pro Gln
                 290                 295                 300

 Lys Leu Ile Pro Pro Gln Pro Thr Gly Arg Pro Ser Pro Ala Pro
                 305                 310                 315

 Pro Ala Val Pro Pro Ala Ala Ser Pro Val Met Pro Pro Gln Thr
                 320                 325                 330

 Gln Ser Pro Gly Gln Pro Ala Gln Pro Ala Pro Met Val Pro Leu
                 335                 340                 345

 His Gln Lys Gln Ser Arg Ile Thr Pro Ile Gln Lys Pro Arg Gly
                 350                 355                 360

 Leu Asp Pro Val Glu Ile Leu Gln Glu Arg Glu Tyr Arg Leu Gln
                 365                 370                 375

 Ala Arg Ile Ala His Arg Ile Gln Glu Leu Glu Asn Leu Pro Gly
                 380                 385                 390

 Ser Leu Ala Gly Asp Leu Arg Thr Lys Ala Thr Ile Glu Leu Lys
                 395                 400                 405

 Ala Leu Arg Leu Leu Asn Phe Gln Arg Gln Leu Arg Gln Glu Val
                 410                 415                 420

 Val Val Cys Met Arg Arg Asp Thr Ala Leu Glu Thr Ala Leu Asn
                 425                 430                 435

 Ala Lys Ala Tyr Lys Arg Ser Lys Arg Gln Ser Leu Arg Glu Ala
                 440                 445                 450

 Arg Ile Thr Glu Lys Leu Glu Lys Gln Gln Lys Ile Glu Gln Glu
                 455                 460                 465

 Arg Lys Arg Arg Gln Lys His Gln Glu Tyr Leu Asn Ser Ile Leu
                 470                 475                 480

 Gln His Ala Lys Asp Phe Lys Glu Tyr His Arg Ser Val Thr Gly
                 485                 490                 495

 Lys Ile Gln Lys Leu Thr Lys Ala Val Ala Thr Tyr His Ala Asn
                 500                 505                 510

 Thr Glu Arg Glu Gln Lys Lys Glu Asn Glu Arg Ile Glu Lys Glu
                 515                 520                 525

 Arg Met Arg Arg Leu Met Ala Glu Asp Glu Glu Gly Tyr Arg Lys
                 530                 535                 540

 Leu Ile Asp Gln Lys Lys Asp Lys Arg Leu Ala Tyr Leu Leu Gln
                 545                 550                 555

 Gln Thr Asp Glu Tyr Val Ala Asn Leu Thr Glu Leu Val Arg Gln
                 560                 565                 570

 His Lys Ala Ala Gln Val Ala Lys Glu Lys Lys Lys Lys Lys Lys
                 575                 580                 585

 Lys Lys Lys Ala Glu Asn Ala Glu Gly Gln Thr Pro Ala Ile Gly
                 590                 595                 600

 Pro Asp Gly Glu Pro Leu Asp Glu Thr Ser Gln Met Ser Asp Leu
                 605                 610                 615

 Pro Val Lys Val Ile His Val Glu Ser Gly Lys Ile Leu Thr Gly
                 620                 625                 630

 Thr Asp Ala Pro Lys Ala Gly Gln Leu Glu Ala Trp Leu Glu Met
                 635                 640                 645

 Asn Pro Gly Tyr Glu Val Ala Pro Arg Ser Asp Ser Glu Glu Ser
                 650                 655                 660

 Gly Ser Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Gln Pro Gln
                 665                 670                 675

 Ala Ala Gln Pro Pro Thr Leu Pro Val Glu Glu Lys Lys Lys Ile
                 680                 685                 690

 Pro Asp Pro Asp Ser Asp Asp Val Ser Glu Val Asp Ala Arg His
                 695                 700                 705

 Ile Ile Glu Asn Ala Lys Gln Asp Val Asp Asp Glu Tyr Gly Val
                 710                 715                 720

 Ser Gln Ala Leu Ala Arg Gly Leu Gln Ser Tyr Tyr Ala Val Ala
                 725                 730                 735

 His Ala Val Thr Glu Arg Val Asp Lys Gln Ser Ala Leu Met Val
                 740                 745                 750

 Asn Gly Val Leu Lys Gln Tyr Gln Ile Lys Gly Leu Glu Trp Leu
                 755                 760                 765

 Val Ser Leu Tyr Asn Asn Asn Leu Asn Gly Ile Leu Ala Asp Glu
                 770                 775                 780

 Met Gly Leu Gly Lys Thr Ile Gln Thr Ile Ala Leu Ile Thr Tyr
                 785                 790                 795

 Leu Met Glu His Lys Arg Ile Asn Gly Pro Phe Leu Ile Ile Val
                 800                 805                 810

 Pro Leu Ser Thr Leu Ser Asn Trp Ala Tyr Glu Phe Asp Lys Trp
                 815                 820                 825

 Ala Pro Ser Val Val Lys Val Ser Tyr Lys Gly Ser Pro Ala Ala
                 830                 835                 840

 Arg Arg Ala Phe Val Pro Gln Leu Arg Ser Gly Lys Phe Asn Val
                 845                 850                 855

 Leu Leu Thr Thr Tyr Glu Tyr Ile Ile Lys Asp Lys His Ile Leu
                 860                 865                 870

 Ala Lys Ile Arg Trp Lys Tyr Met Ile Val Asp Glu Gly His Arg
                 875                 880                 885

 Met Lys Asn His His Cys Lys Leu Thr Gln Val Leu Asn Thr His
                 890                 895                 900

 Tyr Val Ala Pro Arg Arg Leu Leu Leu Thr Gly Thr Pro Leu Gln
                 905                 910                 915

 Asn Lys Leu Pro Glu Leu Trp Ala Leu Leu Asn Phe Leu Leu Pro
                 920                 925                 930

 Thr Ile Phe Lys Ser Cys Ser Thr Phe Glu Gln Trp Phe Asn Ala
                 935                 940                 945

 Pro Phe Ala Met Thr Gly Glu Lys Val Asp Leu Asn Glu Glu Glu
                 950                 955                 960

 Thr Ile Leu Ile Ile Arg Arg Leu His Lys Val Leu Arg Pro Phe
                 965                 970                 975

 Leu Leu Arg Arg Leu Lys Lys Glu Val Glu Ala Gln Leu Pro Glu
                 980                 985                 990

 Lys Val Glu Tyr Val Ile Lys Cys Asp Met Ser Ala Leu Gln Arg
                 995                1000                1005

 Val Leu Tyr Arg His Met Gln Ala Lys Gly Val Leu Leu Thr Asp
                1010                1015                1020

 Gly Ser Glu Lys Asp Lys Lys Gly Lys Gly Gly Thr Lys Thr Leu
                1025                1030                1035

 Met Asn Thr Ile Met Gln Leu Arg Lys Ile Cys Asn His Pro Tyr
                1040                1045                1050

 Met Phe Gln His Ile Glu Glu Ser Phe Ser Glu His Leu Gly Phe
                1055                1060                1065

 Thr Gly Gly Ile Val Gln Gly Leu Asp Leu Tyr Arg Ala Ser Gly
                1070                1075                1080

 Lys Phe Glu Leu Leu Asp Arg Ile Leu Pro Lys Leu Arg Ala Thr
                1085                1090                1095

 Asn His Lys Val Leu Leu Phe Cys Gln Met Thr Ser Leu Met Thr
                1100                1105                1110

 Ile Met Glu Asp Tyr Phe Ala Tyr Arg Gly Phe Lys Tyr Leu Arg
                1115                1120                1125

 Leu Asp Gly Thr Thr Lys Ala Glu Asp Arg Gly Met Leu Leu Lys
                1130                1135                1140

 Thr Phe Asn Glu Pro Gly Ser Glu Tyr Phe Ile Phe Leu Leu Ser
                1145                1150                1155

 Thr Arg Ala Gly Gly Leu Gly Leu Asn Leu Gln Ser Ala Asp Thr
                1160                1165                1170

 Val Ile Ile Phe Asp Ser Asp Trp Asn Pro His Gln Asp Leu Gln
                1175                1180                1185

 Ala Gln Asp Arg Ala His Arg Ile Gly Gln Gln Asn Glu Val Arg
                1190                1195                1200

 Val Leu Arg Leu Cys Thr Val Asn Ser Val Glu Glu Lys Ile Leu
                1205                1210                1215

 Ala Ala Ala Lys Tyr Lys Leu Asn Val Asp Gln Lys Val Ile Gln
                1220                1225                1230

 Ala Gly Met Phe Asp Gln Lys Ser Ser Ser His Glu Arg Arg Ala
                1235                1240                1245

 Phe Leu Gln Ala Ile Leu Glu His Glu Glu Gln Asp Glu Ser Arg
                1250                1255                1260

 His Cys Ser Thr Gly Ser Gly Ser Ala Ser Phe Ala His Thr Ala
                1265                1270                1275

 Pro Pro Pro Ala Gly Val Asn Pro Asp Leu Glu Glu Pro Pro Leu
                1280                1285                1290

 Lys Glu Glu Asp Glu Val Pro Asp Asp Glu Thr Val Asn Gln Met
                1295                1300                1305

 Ile Ala Arg His Glu Glu Glu Phe Asp Leu Phe Met Arg Met Asp
                1310                1315                1320

 Leu Asp Arg Arg Arg Glu Glu Ala Arg Asn Pro Lys Arg Lys Pro
                1325                1330                1335

 Arg Leu Met Glu Glu Asp Glu Leu Pro Ser Trp Ile Ile Lys Asp
                1340                1345                1350

 Asp Ala Glu Val Glu Arg Leu Thr Cys Glu Glu Glu Glu Glu Lys
                1355                1360                1365

 Met Phe Gly Arg Gly Ser Arg His Arg Lys Glu Val Asp Tyr Ser
                1370                1375                1380

 Asp Ser Leu Thr Glu Lys Gln Trp Leu Lys Ala Ile Glu Glu Gly
                1385                1390                1395

 Thr Leu Glu Glu Ile Glu Glu Glu Val Arg Gln Lys Lys Ser Ser
                1400                1405                1410

 Arg Lys Arg Lys Arg Asp Ser Asp Ala Gly Ser Ser Thr Pro Thr
                1415                1420                1425

 Thr Ser Thr Arg Ser Arg Asp Lys Asp Asp Glu Ser Lys Lys Gln
                1430                1435                1440

 Lys Lys Arg Gly Arg Pro Pro Ala Glu Lys Leu Ser Pro Asn Pro
                1445                1450                1455

 Pro Asn Leu Thr Lys Lys Met Lys Lys Ile Val Asp Ala Val Ile
                1460                1465                1470

 Lys Tyr Lys Asp Ser Ser Ser Gly Arg Gln Leu Ser Glu Val Phe
                1475                1480                1485

 Ile Gln Leu Pro Ser Arg Lys Glu Leu Pro Glu Tyr Tyr Glu Leu
                1490                1495                1500

 Ile Arg Lys Pro Val Asp Phe Lys Lys Ile Lys Glu Arg Ile Arg
                1505                1510                1515

 Asn His Lys Tyr Arg Ser Leu Asn Asp Leu Glu Lys Asp Val Met
                1520                1525                1530

 Leu Leu Cys Gln Asn Ala Gln Thr Phe Asn Leu Glu Gly Ser Leu
                1535                1540                1545

 Ile Tyr Glu Asp Ser Ile Val Leu Gln Ser Val Phe Thr Ser Val
                1550                1555                1560

 Arg Gln Lys Ile Glu Lys Glu Asp Asp Ser Glu Gly Glu Glu Ser
                1565                1570                1575

 Glu Glu Glu Glu Glu Gly Glu Glu Glu Gly Ser Glu Ser Glu Ser
                1580                1585                1590

 Arg Ser Val Lys Val Lys Ile Lys Leu Gly Arg Lys Glu Lys Ala
                1595                1600                1605

 Gln Asp Arg Leu Lys Gly Gly Arg Arg Arg Pro Ser Arg Gly Ser
                1610                1615                1620

 Arg Ala Lys Pro Val Val Ser Asp Asp Asp Ser Glu Glu Glu Gln
                1625                1630                1635

 Glu Glu Asp Arg Ser Gly Ser Gly Ser Glu Glu Asp
                1640                1645

<210> 5535
<211> 3455
<212> DNA
<213> Homo sapien

<400> 5535
 ggtttccgga gctgcggcgg cgcagactgg gagggggagc cgggggttcc 50

 gacgtcgcag ccgagggaac aagccccaac cggatcctgg acaggcaccc 100

 cggcttggcg ctgtctctcc ccctcggctc ggagaggccc ttcggcctga 150

 gggagcctcg ccgcccgtcc ccggcacacg cgcagccccg gcctctcggc 200

 ctctgccgga gaaacagttg ggacccctga ttttagcagg atggcccaat 250

 ggaatcagct acagcagctt gacacacggt acctggagca gctccatcag 300

 ctctacagtg acagcttccc aatggagctg cggcagtttc tggccccttg 350

 gattgagagt caagattggg catatgcggc cagcaaagaa tcacatgcca 400

 ctttggtgtt tcataatctc ctgggagaga ttgaccagca gtatagccgc 450

 ttcctgcaag agtcgaatgt tctctatcag cacaatctac gaagaatcaa 500

 gcagtttctt cagagcaggt atcttgagaa gccaatggag attgcccgga 550

 ttgtggcccg gtgcctgtgg gaagaatcac gccttctaca gactgcagcc 600

 actgcggccc agcaaggggg ccaggccaac caccccacag cagccgtggt 650

 gacggagaag cagcagatgc tggagcagca ccttcaggat gtccggaaga 700

 gagtgcagga tctagaacag aaaatgaaag tggtagagaa tctccaggat 750

 gactttgatt tcaactataa aaccctcaag agtcaaggag acatgcaaga 800

 tctgaatgga aacaaccagt cagtgaccag gcagaagatg cagcagctgg 850

 aacagatgct cactgcgctg gaccagatgc ggagaagcat cgtgagtgag 900

 ctggcggggc ttttgtcagc gatggagtac gtgcagaaaa ctctcacgga 950

 cgaggagctg gctgactgga agaggcggca acagattgcc tgcattggag 1000

 gcccgcccaa catctgccta gatcggctag aaaactggat aacgtcatta 1050

 gcagaatctc aacttcagac ccgtcaacaa attaagaaac tggaggagtt 1100

 gcagcaaaaa gtttcctaca aaggggaccc cattgtacag caccggccga 1150

 tgctggagga gagaatcgtg gagctgttta gaaacttaat gaaaagtgcc 1200

 tttgtggtgg agcggcagcc ctgcatgccc atgcatcctg accggcccct 1250

 cgtcatcaag accggcgtcc agttcactac taaagtcagg ttgctggtca 1300

 aattccctga gttgaattat cagcttaaaa ttaaagtgtg cattgacaaa 1350

 gactctgggg acgttgcagc tctcagagga tcccggaaat ttaacattct 1400

 gggcacaaac acaaaagtga tgaacatgga agaatccaac aacggcagcc 1450

 tctctgcaga attcaaacac ttgaccctga gggagcagag atgtgggaat 1500

 gggggccgag ccaattgtga tgcttccctg attgtgactg aggagctgca 1550

 cctgatcacc tttgagaccg aggtgtatca ccaaggcctc aagattgacc 1600

 tagagaccca ctccttgcca gttgtggtga tctccaacat ctgtcagatg 1650

 ccaaatgcct gggcgtccat cctgtggtac aacatgctga ccaacaatcc 1700

 caagaatgta aactttttta ccaagccccc aattggaacc tgggatcaag 1750

 tggccgaggt cctgagctgg cagttctcct ccaccaccaa gcgaggactg 1800

 agcatcgagc agctgactac actggcagag aaactcttgg gacctggtgt 1850

 gaattattca gggtgtcaga tcacatgggc taaattttgc aaagaaaaca 1900

 tggctggcaa gggcttctcc ttctgggtct ggctggacaa tatcattgac 1950

 cttgtgaaaa agtacatcct ggccctttgg aacgaagggt acatcatggg 2000

 ctttatcagt aaggagcggg agcgggccat cttgagcact aagcctccag 2050

 gcaccttcct gctaagattc agtgaaagca gcaaagaagg aggcgtcact 2100

 ttcacttggg tggagaagga catcagcggt aagacccaga tccagtccgt 2150

 ggaaccatac acaaagcagc agctgaacaa catgtcattt gctgaaatca 2200

 tcatgggcta taagatcatg gatgctacca atatcctggt gtctccactg 2250

 gtctatctct atcctgacat tcccaaggag gaggcattcg gaaagtattg 2300

 tcggccagag agccaggagc atcctgaagc tgacccaggt agcgctgccc 2350

 catacctgaa gaccaagttt atctgtgtga caccaacgac ctgcagcaat 2400

 accattgacc tgccgatgtc cccccgcact ttagattcat tgatgcagtt 2450

 tggaaataat ggtgaaggtg ctgaaccctc agcaggaggg cagtttgagt 2500

 ccctcacctt tgacatggag ttgacctcgg agtgcgctac ctcccccatg 2550

 tgaggagctg agaacggaag ctgcagaaag atacgactga ggcgcctacc 2600

 tgcattctgc cacccctcac acagccaaac cccagatcat ctgaaactac 2650

 taactttgtg gttccagatt ttttttaatc tcctacttct gctatctttg 2700

 agcaatctgg gcacttttaa aaatagagaa atgagtgaat gtgggtgatc 2750

 tgcttttatc taaatgcaaa taaggatgtg ttctctgaga cccatgatca 2800

 ggggatgtgg cggggggtgg ctagagggag aaaaaggaaa tgtcttgtgt 2850

 tgttttgttc ccctgccctc ctttctcagc agctttttgt tattgttgtt 2900

 gttgttctta gacaagtgcc tcctggtgcc tgcggcatcc ttctgcctgt 2950

 ttctgtaagc aaatgccaca ggccacctat agctacatac tcctggcatt 3000

 gcacttttta accttgctga catccaaata gaagatagga ctatctaagc 3050

 cctaggtttc tttttaaatt aagaaataat aacaattaaa gggcaaaaaa 3100

 cactgtatca gcatagcctt tctgtattta agaaacttaa gcagccgggc 3150

 atggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcggatc 3200

 ataaggtcag gagatcaaga ccatcctggc taacacggtg aaaccccgtc 3250

 tctactaaaa gtacaaaaaa ttagctgggt gtggtggtgg gcgcctgtag 3300

 tcccagctac tcgggaggct gaggcaggag aatcgcttga acctgagagg 3350

 cggaggttgc agtgagccaa aattgcacca ctgcacactg cactccatcc 3400

 tgggcgacag tctgagactc tgtctcaaaa aaaaaaaaaa aaaaaaaaaa 3450

 aaaaa 3455

<210> 5536
<211> 770
<212> PRT
<213> Homo sapien

<400> 5536
 Met Ala Gln Trp Asn Gln Leu Gln Gln Leu Asp Thr Arg Tyr Leu
   1               5                  10                  15

 Glu Gln Leu His Gln Leu Tyr Ser Asp Ser Phe Pro Met Glu Leu
                  20                  25                  30

 Arg Gln Phe Leu Ala Pro Trp Ile Glu Ser Gln Asp Trp Ala Tyr
                  35                  40                  45

 Ala Ala Ser Lys Glu Ser His Ala Thr Leu Val Phe His Asn Leu
                  50                  55                  60

 Leu Gly Glu Ile Asp Gln Gln Tyr Ser Arg Phe Leu Gln Glu Ser
                  65                  70                  75

 Asn Val Leu Tyr Gln His Asn Leu Arg Arg Ile Lys Gln Phe Leu
                  80                  85                  90

 Gln Ser Arg Tyr Leu Glu Lys Pro Met Glu Ile Ala Arg Ile Val
                  95                 100                 105

 Ala Arg Cys Leu Trp Glu Glu Ser Arg Leu Leu Gln Thr Ala Ala
                 110                 115                 120

 Thr Ala Ala Gln Gln Gly Gly Gln Ala Asn His Pro Thr Ala Ala
                 125                 130                 135

 Val Val Thr Glu Lys Gln Gln Met Leu Glu Gln His Leu Gln Asp
                 140                 145                 150

 Val Arg Lys Arg Val Gln Asp Leu Glu Gln Lys Met Lys Val Val
                 155                 160                 165

 Glu Asn Leu Gln Asp Asp Phe Asp Phe Asn Tyr Lys Thr Leu Lys
                 170                 175                 180

 Ser Gln Gly Asp Met Gln Asp Leu Asn Gly Asn Asn Gln Ser Val
                 185                 190                 195

 Thr Arg Gln Lys Met Gln Gln Leu Glu Gln Met Leu Thr Ala Leu
                 200                 205                 210

 Asp Gln Met Arg Arg Ser Ile Val Ser Glu Leu Ala Gly Leu Leu
                 215                 220                 225

 Ser Ala Met Glu Tyr Val Gln Lys Thr Leu Thr Asp Glu Glu Leu
                 230                 235                 240

 Ala Asp Trp Lys Arg Arg Gln Gln Ile Ala Cys Ile Gly Gly Pro
                 245                 250                 255

 Pro Asn Ile Cys Leu Asp Arg Leu Glu Asn Trp Ile Thr Ser Leu
                 260                 265                 270

 Ala Glu Ser Gln Leu Gln Thr Arg Gln Gln Ile Lys Lys Leu Glu
                 275                 280                 285

 Glu Leu Gln Gln Lys Val Ser Tyr Lys Gly Asp Pro Ile Val Gln
                 290                 295                 300

 His Arg Pro Met Leu Glu Glu Arg Ile Val Glu Leu Phe Arg Asn
                 305                 310                 315

 Leu Met Lys Ser Ala Phe Val Val Glu Arg Gln Pro Cys Met Pro
                 320                 325                 330

 Met His Pro Asp Arg Pro Leu Val Ile Lys Thr Gly Val Gln Phe
                 335                 340                 345

 Thr Thr Lys Val Arg Leu Leu Val Lys Phe Pro Glu Leu Asn Tyr
                 350                 355                 360

 Gln Leu Lys Ile Lys Val Cys Ile Asp Lys Asp Ser Gly Asp Val
                 365                 370                 375

 Ala Ala Leu Arg Gly Ser Arg Lys Phe Asn Ile Leu Gly Thr Asn
                 380                 385                 390

 Thr Lys Val Met Asn Met Glu Glu Ser Asn Asn Gly Ser Leu Ser
                 395                 400                 405

 Ala Glu Phe Lys His Leu Thr Leu Arg Glu Gln Arg Cys Gly Asn
                 410                 415                 420

 Gly Gly Arg Ala Asn Cys Asp Ala Ser Leu Ile Val Thr Glu Glu
                 425                 430                 435

 Leu His Leu Ile Thr Phe Glu Thr Glu Val Tyr His Gln Gly Leu
                 440                 445                 450

 Lys Ile Asp Leu Glu Thr His Ser Leu Pro Val Val Val Ile Ser
                 455                 460                 465

 Asn Ile Cys Gln Met Pro Asn Ala Trp Ala Ser Ile Leu Trp Tyr
                 470                 475                 480

 Asn Met Leu Thr Asn Asn Pro Lys Asn Val Asn Phe Phe Thr Lys
                 485                 490                 495

 Pro Pro Ile Gly Thr Trp Asp Gln Val Ala Glu Val Leu Ser Trp
                 500                 505                 510

 Gln Phe Ser Ser Thr Thr Lys Arg Gly Leu Ser Ile Glu Gln Leu
                 515                 520                 525

 Thr Thr Leu Ala Glu Lys Leu Leu Gly Pro Gly Val Asn Tyr Ser
                 530                 535                 540

 Gly Cys Gln Ile Thr Trp Ala Lys Phe Cys Lys Glu Asn Met Ala
                 545                 550                 555

 Gly Lys Gly Phe Ser Phe Trp Val Trp Leu Asp Asn Ile Ile Asp
                 560                 565                 570

 Leu Val Lys Lys Tyr Ile Leu Ala Leu Trp Asn Glu Gly Tyr Ile
                 575                 580                 585

 Met Gly Phe Ile Ser Lys Glu Arg Glu Arg Ala Ile Leu Ser Thr
                 590                 595                 600

 Lys Pro Pro Gly Thr Phe Leu Leu Arg Phe Ser Glu Ser Ser Lys
                 605                 610                 615

 Glu Gly Gly Val Thr Phe Thr Trp Val Glu Lys Asp Ile Ser Gly
                 620                 625                 630

 Lys Thr Gln Ile Gln Ser Val Glu Pro Tyr Thr Lys Gln Gln Leu
                 635                 640                 645

 Asn Asn Met Ser Phe Ala Glu Ile Ile Met Gly Tyr Lys Ile Met
                 650                 655                 660

 Asp Ala Thr Asn Ile Leu Val Ser Pro Leu Val Tyr Leu Tyr Pro
                 665                 670                 675

 Asp Ile Pro Lys Glu Glu Ala Phe Gly Lys Tyr Cys Arg Pro Glu
                 680                 685                 690

 Ser Gln Glu His Pro Glu Ala Asp Pro Gly Ser Ala Ala Pro Tyr
                 695                 700                 705

 Leu Lys Thr Lys Phe Ile Cys Val Thr Pro Thr Thr Cys Ser Asn
                 710                 715                 720

 Thr Ile Asp Leu Pro Met Ser Pro Arg Thr Leu Asp Ser Leu Met
                 725                 730                 735

 Gln Phe Gly Asn Asn Gly Glu Gly Ala Glu Pro Ser Ala Gly Gly
                 740                 745                 750

 Gln Phe Glu Ser Leu Thr Phe Asp Met Glu Leu Thr Ser Glu Cys
                 755                 760                 765

 Ala Thr Ser Pro Met
                 770

<210> 5537
<211> 2910
<212> DNA
<213> Homo sapien

<400> 5537
 gcccaggtga ctgactaatc cgccgccttc aggagacaga attggccaag 50

 gcctgaaggc cccggagtgc accagcggca tgtacaaaga gaccgtctac 100

 tccgccttca atctgctcat gcattaccca cccccctcgg gagcagggca 150

 gcacccccag ccgcagcccc cgctgcacaa ggccaatcag cccccccacg 200

 gtgtccccca actctctctc tacgaacatt tcaacagccc acatcccacc 250

 cctgcacctg cggacatcag ccagaagcaa gttcacaggc ctctgcagac 300

 ccctgacctc tctggcttct actccctgac ctcaggcagc atggggcagc 350

 tcccccacac tgtgagctgg ttcacccacc catccttgat gctaggttct 400

 ggtgtacctg gtcacccagc agccatcccc cacccggcca ttgtgccccc 450

 ctcagggaag caggagctgc agcccttcga ccgcaacctg aagacacaag 500

 cagagtccaa ggcagagaag gaggccaaga agccaaccat caagaagccc 550

 ctcaatgcct tcatgctgta catgaaggag atgagagcca aggtcattgc 600

 agagtgcaca cttaaggaga gcgctgccat caaccagatc ctgggccgca 650

 ggtggcacgc gctgtcgcga gaagagcagg ccaagtacta tgagctggcc 700

 cgcaaggaga ggcagctgca catgcagcta tacccaggct ggtcagcgcg 750

 ggacaactac gggaagaaga agaggcggtc gagggaaaag caccaagaat 800

 ccaccacaga ccctggctcg cctaagaaat gccgtgctcg ctttggcctc 850

 aaccagcaga cggattggtg tggtccgtgc agataactct cttcactatt 900

 cctaggagga aaaagaaatg cattcggtac ttacccggag aaggccgctg 950

 ccccagcccc gttccttccg atgacagtgc tctaggctgc cccgggtccc 1000

 cagctcccca ggactcaccc tcataccatc tgctgccccg cttccccaca 1050

 gaactgctta ctagccctgc ggagcggcac ctacatcccc aggtctctcc 1100

 actgctctca gcctcccaac cccagggccc ccacaggccc cccgcagcac 1150

 cctgcagagc acacaggtac agcaacagga atctcagaga caggtggcct 1200

 agcaggcaca ggacacctgg ccgcctccag gagcctaccc cctgaaaatg 1250

 acagagaccc agatctcatg gaaactggca ggggtcctgt taacgtcatc 1300

 tcagggtcca gaccctgaag atttcagagg ctgcagaact tctgcctgaa 1350

 cctggggtca tcgattcaaa ctgctccaag tggtgggaat cagatctgtc 1400

 ttgatgtgtc atctaattaa gggaatccct tgtacctatg actccgtcga 1450

 tctattcttt gtaccatctg tcttgccagc cagaagcctc tgcctcccta 1500

 gcttttctgc tataggtcag agatgggctg aactgagcct agctaccttc 1550

 tctacccatc tcccccatcc cccactgcca caccctcccc attcagacac 1600

 ttcatggacc aagaatgagc tggtttgtca aacaacatgt gagcatggtc 1650

 acaagcacaa agctcaagat gacagctctt ctaaggaaat ggagaagctc 1700

 tgtttataaa aacaaaaaca aaaccagctg ctactcataa gttggaccag 1750

 aggaagcccc ttactatgat ctcaggagct tgcaagaagc aggaagggga 1800

 atggaatagg ttaagtttag gcctatcaac ctaagcaaca gaaataatct 1850

 gacactacct tatcaggcaa attggggagg ggagggtgta tctagctcta 1900

 gttcaaatta tttggaagtg ttccctgaga aacccaccag cctaagaagc 1950

 tctggcccca ggcttgtcac tagcagctgc agtcaacagt tcaaagaagt 2000

 catggcccaa atccagtgtg cacccctccc cattcacaga gcctttttca 2050

 caattccatt tccagttcat ctatggcagt ccagccagct tctgggcagc 2100

 ttgagagggc aaacccaaaa cctcatgaca gccagagcct gtctttcagc 2150

 attcagtcgc ctgggaagct ccagtttccc catggggctg cgggacagag 2200

 gaccattaca actagatcaa ggagcccaga aaacctccag tagtggacaa 2250

 caggttttca ccatagccta cgttaaccca tttttgagcc aagcttcaac 2300

 cctcagcctt gaaaaacaag tctttaattt aatttttgtt ttttgcctaa 2350

 atccaaagaa aaagggctgc cgggccaggc gcggtcgtca cgcctgtaat 2400

 cccagcactt tggcaggccg aggcaggtgg atcacctgac gtcagtagtt 2450

 tgagaccagc ctggccaaca tggtgaaacc ctgtatctac taaaaataca 2500

 aaaattagcc ggacgtggtg gtgcgcgcat gtaatcccag ctactcggga 2550

 ggctgaggcg gaagaatcac ttgaacccgg gaggcggagg ttccagtgag 2600

 ccgagatggc gctattgcac tccagtctgg gtaacaggga gactgcatct 2650

 caaaaaaaaa aaaaaaaaaa aagggctgtc catgtattca cacacccctc 2700

 aaaaaaagcc tttagttcct actttagcca ctggtttctc agaatccaaa 2750

 gatcacatat tctagtgtaa cactgcaaga agtcttgaga aaaagattat 2800

 tgtagtgttc aaaatatttt tgtattgtta atgcatcatc atagaaaaac 2850

 ttttaaacat gagaataaag atacttttta ctgggtttgt ttttcaaagc 2900

 ctgaaaaaaa 2910

<210> 5538
<211> 268
<212> PRT
<213> Homo sapien

<400> 5538
 Met Tyr Lys Glu Thr Val Tyr Ser Ala Phe Asn Leu Leu Met His
   1               5                  10                  15

 Tyr Pro Pro Pro Ser Gly Ala Gly Gln His Pro Gln Pro Gln Pro
                  20                  25                  30

 Pro Leu His Lys Ala Asn Gln Pro Pro His Gly Val Pro Gln Leu
                  35                  40                  45

 Ser Leu Tyr Glu His Phe Asn Ser Pro His Pro Thr Pro Ala Pro
                  50                  55                  60

 Ala Asp Ile Ser Gln Lys Gln Val His Arg Pro Leu Gln Thr Pro
                  65                  70                  75

 Asp Leu Ser Gly Phe Tyr Ser Leu Thr Ser Gly Ser Met Gly Gln
                  80                  85                  90

 Leu Pro His Thr Val Ser Trp Phe Thr His Pro Ser Leu Met Leu
                  95                 100                 105

 Gly Ser Gly Val Pro Gly His Pro Ala Ala Ile Pro His Pro Ala
                 110                 115                 120

 Ile Val Pro Pro Ser Gly Lys Gln Glu Leu Gln Pro Phe Asp Arg
                 125                 130                 135

 Asn Leu Lys Thr Gln Ala Glu Ser Lys Ala Glu Lys Glu Ala Lys
                 140                 145                 150

 Lys Pro Thr Ile Lys Lys Pro Leu Asn Ala Phe Met Leu Tyr Met
                 155                 160                 165

 Lys Glu Met Arg Ala Lys Val Ile Ala Glu Cys Thr Leu Lys Glu
                 170                 175                 180

 Ser Ala Ala Ile Asn Gln Ile Leu Gly Arg Arg Trp His Ala Leu
                 185                 190                 195

 Ser Arg Glu Glu Gln Ala Lys Tyr Tyr Glu Leu Ala Arg Lys Glu
                 200                 205                 210

 Arg Gln Leu His Met Gln Leu Tyr Pro Gly Trp Ser Ala Arg Asp
                 215                 220                 225

 Asn Tyr Gly Lys Lys Lys Arg Arg Ser Arg Glu Lys His Gln Glu
                 230                 235                 240

 Ser Thr Thr Asp Pro Gly Ser Pro Lys Lys Cys Arg Ala Arg Phe
                 245                 250                 255

 Gly Leu Asn Gln Gln Thr Asp Trp Cys Gly Pro Cys Arg
                 260                 265

<210> 5539
<211> 5010
<212> DNA
<213> Homo sapien

<400> 5539
 ggcggctcgg gacggaggac gcgctagtgt gagtgcgggc ttctagaact 50

 acaccgaccc tcgtgtcctc ccttcatcct gcggggctgg ctggagcggc 100

 cgctccggtg ctgtccagca gccataggga gccgcacggg gagcgggaaa 150

 gcggtcgcgg ccccaggcgg ggcggccggg atggagcggg gccgcgagcc 200

 tgtggggaag gggctgtggc ggcgcctcga gcggctgcag gttcttctgt 250

 gtggcagttc agaatgatgg atcaagctag atcagcattc tctaacttgt 300

 ttggtggaga accattgtca tatacccggt tcagcctggc tcggcaagta 350

 gatggcgata acagtcatgt ggagatgaaa cttgctgtag atgaagaaga 400

 aaatgctgac aataacacaa aggccaatgt cacaaaacca aaaaggtgta 450

 gtggaagtat ctgctatggg actattgctg tgatcgtctt tttcttgatt 500

 ggatttatga ttggctactt gggctattgt aaaggggtag aaccaaaaac 550

 tgagtgtgag agactggcag gaaccgagtc tccagtgagg gaggagccag 600

 gagaggactt ccctgcagca cgtcgcttat attgggatga cctgaagaga 650

 aagttgtcgg agaaactgga cagcacagac ttcaccagca ccatcaagct 700

 gctgaatgaa aattcatatg tccctcgtga ggctggatct caaaaagatg 750

 aaaatcttgc gttgtatgtt gaaaatcaat ttcgtgaatt taaactcagc 800

 aaagtctggc gtgatcaaca ttttgttaag attcaggtca aagacagcgc 850

 tcaaaactcg gtgatcatag ttgataagaa cggtagactt gtttacctgg 900

 tggagaatcc tgggggttat gtggcgtata gtaaggctgc aacagttact 950

 ggtaaactgg tccatgctaa ttttggtact aaaaaagatt ttgaggattt 1000

 atacactcct gtgaatggat ctatagtgat tgtcagagca gggaaaatca 1050

 cctttgcaga aaaggttgca aatgctgaaa gcttaaatgc aattggtgtg 1100

 ttgatataca tggaccagac taaatttccc attgttaacg cagaactttc 1150

 attctttgga catgctcatc tggggacagg tgacccttac acacctggat 1200

 tcccttcctt caatcacact cagtttccac catctcggtc atcaggattg 1250

 cctaatatac ctgtccagac aatctccaga gctgctgcag aaaagctgtt 1300

 tgggaatatg gaaggagact gtccctctga ctggaaaaca gactctacat 1350

 gtaggatggt aacctcagaa agcaagaatg tgaagctcac tgtgagcaat 1400

 gtgctgaaag agataaaaat tcttaacatc tttggagtta ttaaaggctt 1450

 tgtagaacca gatcactatg ttgtagttgg ggcccagaga gatgcatggg 1500

 gccctggagc tgcaaaatcc ggtgtaggca cagctctcct attgaaactt 1550

 gcccagatgt tctcagatat ggtcttaaaa gatgggtttc agcccagcag 1600

 aagcattatc tttgccagtt ggagtgctgg agactttgga tcggttggtg 1650

 ccactgaatg gctagaggga tacctttcgt ccctgcattt aaaggctttc 1700

 acttatatta atctggataa agcggttctt ggtaccagca acttcaaggt 1750

 ttctgccagc ccactgttgt atacgcttat tgagaaaaca atgcaaaatg 1800

 tgaagcatcc ggttactggg caatttctat atcaggacag caactgggcc 1850

 agcaaagttg agaaactcac tttagacaat gctgctttcc ctttccttgc 1900

 atattctgga atcccagcag tttctttctg tttttgcgag gacacagatt 1950

 atccttattt gggtaccacc atggacacct ataaggaact gattgagagg 2000

 attcctgagt tgaacaaagt ggcacgagca gctgcagagg tcgctggtca 2050

 gttcgtgatt aaactaaccc atgatgttga attgaacctg gactatgaga 2100

 ggtacaacag ccaactgctt tcatttgtga gggatctgaa ccaatacaga 2150

 gcagacataa aggaaatggg cctgagttta cagtggctgt attctgctcg 2200

 tggagacttc ttccgtgcta cttccagact aacaacagat ttcgggaatg 2250

 ctgagaaaac agacagattt gtcatgaaga aactcaatga tcgtgtcatg 2300

 agagtggagt atcacttcct ctctccctac gtatctccaa aagagtctcc 2350

 tttccgacat gtcttctggg gctccggctc tcacacgctg ccagctttac 2400

 tggagaactt gaaactgcgt aaacaaaata acggtgcttt taatgaaacg 2450

 ctgttcagaa accagttggc tctagctact tggactattc agggagctgc 2500

 aaatgccctc tctggtgacg tttgggacat tgacaatgag ttttaaatgt 2550

 gatacccata gcttccatga gaacagcagg gtagtctggt ttctagactt 2600

 gtgctgatcg tgctaaattt tcagtagggc tacaaaacct gatgttaaaa 2650

 ttccatccca tcatcttggt actactagat gtctttaggc agcagctttt 2700

 aatacagggt agataacctg tacttcaagt taaagtgaat aaccacttaa 2750

 aaaatgtcca tgatggaata ttcccctatc tctagaattt taagtgcttt 2800

 gtaatgggaa ctgcctcttt cctgttgttg ttaatgaaaa tgtcagaaac 2850

 cagttatgtg aatgatctct ctgaatccta agggctggtc tctgctgaag 2900

 gttgtaagtg gttcgcttac tttgagtgat cctccaactt catttgatgc 2950

 taaataggag ataccaggtt gaaagacctc tccaaatgag atctaagcct 3000

 ttccataagg aatgtagcag gtttcctcat tcctgaaaga aacagttaac 3050

 tttcagaaga gatgggcttg ttttcttgcc aatgaggtct gaaatggagg 3100

 tccttctgct ggataaaatg aggttcaact gttgattgca ggaataaggc 3150

 cttaatatgt taacctcagt gtcatttatg aaaagagggg accagaagcc 3200

 aaagacttag tatattttct tttcctctgt cccttccccc ataagcctcc 3250

 atttagttct ttgttatttt tgtttcttcc aaagcacatt gaaagagaac 3300

 cagtttcagg tgtttagttg cagactcagt ttgtcagact ttaaagaata 3350

 atatgctgcc aaattttggc caaagtgtta atcttagggg agagctttct 3400

 gtccttttgg cactgagata tttattgttt atttatcagt gacagagttc 3450

 actataaatg gtgttttttt aatagaatat aattatcgga agcagtgcct 3500

 tccataatta tgacagttat actgtcggtt ttttttaaat aaaagcagca 3550

 tctgctaata aaacccaaca gatactggaa gttttgcatt tatggtcaac 3600

 acttaagggt tttagaaaac agccgtcagc caaatgtaat tgaataaagt 3650

 tgaagctaag atttagagat gaattaaatt taattagggg ttgctaagaa 3700

 gcgagcactg accagataag aatgctggtt ttcctaaatg cagtgaattg 3750

 tgaccaagtt ataaatcaat gtcacttaaa ggctgtggta gtactcctgc 3800

 aaaattttat agctcagttt atccaaggtg taactctaat tcccatttgc 3850

 aaaatttcca gtacctttgt cacaatccta acacattatc gggagcagtg 3900

 tcttccataa tgtataaaga acaaggtagt ttttacctac cacagtgtct 3950

 gtatcggaga cagtgatctc catatgttac actaagggtg taagtaatta 4000

 tcgggaacag tgtttcccat aattttcttc atgcaatgac atcttcaaag 4050

 cttgaagatc gttagtatct aacatgtatc ccaactccta taattcccta 4100

 tcttttagtt ttagttgcag aaacattttg tggtcattaa gcattgggtg 4150

 ggtaaattca accactgtaa aatgaaatta ctacaaaatt tgaaatttag 4200

 cttgggtttt tgttaccttt atggtttctc caggtcctct acttaatgag 4250

 atagcagcat acatttataa tgtttgctat tgacaagtca ttttaattta 4300

 tcacattatt tgcatgttac ctcctataaa cttagtgcgg acaagtttta 4350

 atccagaatt gaccttttga cttaaagcag agggactttg tatagaaggt 4400

 ttgggggctg tggggaagga gagtcccctg aaggtctgac acgtctgcct 4450

 acccattcgt ggtgatcaat taaatgtagg tatgaataag ttcgaagctc 4500

 cgtgagtgaa ccatcatata aacgtgtagt acagctgttt gtcatagggc 4550

 agttggaaac ggcctcctag ggaaaagttc atagggtctc ttcaggttct 4600

 tagtgtcact tacctagatt tacagcctca cttgaatgtg tcactactca 4650

 cagtctcttt aatcttcagt tttatcttta atctcctctt ttatcttgga 4700

 ctgacattta gcgtagctaa gtgaaaaggt catagctgag attcctggtt 4750

 cgggtgttac gcacacgtac ttaaatgaaa gcatgtggca tgttcatcgt 4800

 ataacacaat atgaatacag ggcatgcatt ttgcagcagt gagtctcttc 4850

 agaaaaccct tttctacagt tagggttgag ttacttccta tcaagccagt 4900

 acgtgctaac aggctcaata ttcctgaatg aaatatcaga ctagtgacaa 4950

 gctcctggtc ttgagatgtc ttctcgttaa ggagtagggc cttttggagg 5000

 taaaggtata 5010

<210> 5540
<211> 760
<212> PRT
<213> Homo sapien

<400> 5540
 Met Met Asp Gln Ala Arg Ser Ala Phe Ser Asn Leu Phe Gly Gly
   1               5                  10                  15

 Glu Pro Leu Ser Tyr Thr Arg Phe Ser Leu Ala Arg Gln Val Asp
                  20                  25                  30

 Gly Asp Asn Ser His Val Glu Met Lys Leu Ala Val Asp Glu Glu
                  35                  40                  45

 Glu Asn Ala Asp Asn Asn Thr Lys Ala Asn Val Thr Lys Pro Lys
                  50                  55                  60

 Arg Cys Ser Gly Ser Ile Cys Tyr Gly Thr Ile Ala Val Ile Val
                  65                  70                  75

 Phe Phe Leu Ile Gly Phe Met Ile Gly Tyr Leu Gly Tyr Cys Lys
                  80                  85                  90

 Gly Val Glu Pro Lys Thr Glu Cys Glu Arg Leu Ala Gly Thr Glu
                  95                 100                 105

 Ser Pro Val Arg Glu Glu Pro Gly Glu Asp Phe Pro Ala Ala Arg
                 110                 115                 120

 Arg Leu Tyr Trp Asp Asp Leu Lys Arg Lys Leu Ser Glu Lys Leu
                 125                 130                 135

 Asp Ser Thr Asp Phe Thr Ser Thr Ile Lys Leu Leu Asn Glu Asn
                 140                 145                 150

 Ser Tyr Val Pro Arg Glu Ala Gly Ser Gln Lys Asp Glu Asn Leu
                 155                 160                 165

 Ala Leu Tyr Val Glu Asn Gln Phe Arg Glu Phe Lys Leu Ser Lys
                 170                 175                 180

 Val Trp Arg Asp Gln His Phe Val Lys Ile Gln Val Lys Asp Ser
                 185                 190                 195

 Ala Gln Asn Ser Val Ile Ile Val Asp Lys Asn Gly Arg Leu Val
                 200                 205                 210

 Tyr Leu Val Glu Asn Pro Gly Gly Tyr Val Ala Tyr Ser Lys Ala
                 215                 220                 225

 Ala Thr Val Thr Gly Lys Leu Val His Ala Asn Phe Gly Thr Lys
                 230                 235                 240

 Lys Asp Phe Glu Asp Leu Tyr Thr Pro Val Asn Gly Ser Ile Val
                 245                 250                 255

 Ile Val Arg Ala Gly Lys Ile Thr Phe Ala Glu Lys Val Ala Asn
                 260                 265                 270

 Ala Glu Ser Leu Asn Ala Ile Gly Val Leu Ile Tyr Met Asp Gln
                 275                 280                 285

 Thr Lys Phe Pro Ile Val Asn Ala Glu Leu Ser Phe Phe Gly His
                 290                 295                 300

 Ala His Leu Gly Thr Gly Asp Pro Tyr Thr Pro Gly Phe Pro Ser
                 305                 310                 315

 Phe Asn His Thr Gln Phe Pro Pro Ser Arg Ser Ser Gly Leu Pro
                 320                 325                 330

 Asn Ile Pro Val Gln Thr Ile Ser Arg Ala Ala Ala Glu Lys Leu
                 335                 340                 345

 Phe Gly Asn Met Glu Gly Asp Cys Pro Ser Asp Trp Lys Thr Asp
                 350                 355                 360

 Ser Thr Cys Arg Met Val Thr Ser Glu Ser Lys Asn Val Lys Leu
                 365                 370                 375

 Thr Val Ser Asn Val Leu Lys Glu Ile Lys Ile Leu Asn Ile Phe
                 380                 385                 390

 Gly Val Ile Lys Gly Phe Val Glu Pro Asp His Tyr Val Val Val
                 395                 400                 405

 Gly Ala Gln Arg Asp Ala Trp Gly Pro Gly Ala Ala Lys Ser Gly
                 410                 415                 420

 Val Gly Thr Ala Leu Leu Leu Lys Leu Ala Gln Met Phe Ser Asp
                 425                 430                 435

 Met Val Leu Lys Asp Gly Phe Gln Pro Ser Arg Ser Ile Ile Phe
                 440                 445                 450

 Ala Ser Trp Ser Ala Gly Asp Phe Gly Ser Val Gly Ala Thr Glu
                 455                 460                 465

 Trp Leu Glu Gly Tyr Leu Ser Ser Leu His Leu Lys Ala Phe Thr
                 470                 475                 480

 Tyr Ile Asn Leu Asp Lys Ala Val Leu Gly Thr Ser Asn Phe Lys
                 485                 490                 495

 Val Ser Ala Ser Pro Leu Leu Tyr Thr Leu Ile Glu Lys Thr Met
                 500                 505                 510

 Gln Asn Val Lys His Pro Val Thr Gly Gln Phe Leu Tyr Gln Asp
                 515                 520                 525

 Ser Asn Trp Ala Ser Lys Val Glu Lys Leu Thr Leu Asp Asn Ala
                 530                 535                 540

 Ala Phe Pro Phe Leu Ala Tyr Ser Gly Ile Pro Ala Val Ser Phe
                 545                 550                 555

 Cys Phe Cys Glu Asp Thr Asp Tyr Pro Tyr Leu Gly Thr Thr Met
                 560                 565                 570

 Asp Thr Tyr Lys Glu Leu Ile Glu Arg Ile Pro Glu Leu Asn Lys
                 575                 580                 585

 Val Ala Arg Ala Ala Ala Glu Val Ala Gly Gln Phe Val Ile Lys
                 590                 595                 600

 Leu Thr His Asp Val Glu Leu Asn Leu Asp Tyr Glu Arg Tyr Asn
                 605                 610                 615

 Ser Gln Leu Leu Ser Phe Val Arg Asp Leu Asn Gln Tyr Arg Ala
                 620                 625                 630

 Asp Ile Lys Glu Met Gly Leu Ser Leu Gln Trp Leu Tyr Ser Ala
                 635                 640                 645

 Arg Gly Asp Phe Phe Arg Ala Thr Ser Arg Leu Thr Thr Asp Phe
                 650                 655                 660

 Gly Asn Ala Glu Lys Thr Asp Arg Phe Val Met Lys Lys Leu Asn
                 665                 670                 675

 Asp Arg Val Met Arg Val Glu Tyr His Phe Leu Ser Pro Tyr Val
                 680                 685                 690

 Ser Pro Lys Glu Ser Pro Phe Arg His Val Phe Trp Gly Ser Gly
                 695                 700                 705

 Ser His Thr Leu Pro Ala Leu Leu Glu Asn Leu Lys Leu Arg Lys
                 710                 715                 720

 Gln Asn Asn Gly Ala Phe Asn Glu Thr Leu Phe Arg Asn Gln Leu
                 725                 730                 735

 Ala Leu Ala Thr Trp Thr Ile Gln Gly Ala Ala Asn Ala Leu Ser
                 740                 745                 750

 Gly Asp Val Trp Asp Ile Asp Asn Glu Phe
                 755                 760

<210> 5541
<211> 4208
<212> DNA
<213> Homo sapien

<400> 5541
 tctttaagat ttgtagctac taagaaagaa aggagctttt tttccttggg 50

 ccttcaaact gaaagaaccg catgagcctg acggcgcatg gtcttaacat 100

 caggctgtgc aggaagaagc tatctgcaga tggatgccag cacacacaag 150

 gaagcagagc tctggcaaca ttgagtcaaa gcaaggacac aacatcagag 200

 ggacggcaga gaatccttgt gtgtagtctt tggtggcagt ttgaaaattg 250

 caaggaggga ctttaagact acttctgatt tgcaaagatg gtctgtgctc 300

 cgagcaggct aaagtgactg gacgagacgc actgttggag aaataaaaat 350

 gacttcccat tatgtgattg ccatctttgc cctgatgagc ttctgtttag 400

 ccactgcagg tccagagcct ggtgcactgt gtgaactgtc acctgtcagt 450

 gcctcccatc ctgtccaggc cttgatggag agcttcactg ttttgtcagg 500

 ctgtgccagc agaggcacaa ctgggctgcc acaggaggtg catgtcctga 550

 atctcgcact gcgccagggg cctggccagc tacagagaga ggtcacactt 600

 cacctgaatc ccatctcctc agtccacatc caccacaagt ctgttgtgtt 650

 cctgctcaac tccccacacc ccctggtgtg gcatctgaag acagagagac 700

 ttgccactgg ggtctccaga ctgtttttgg tgtctgaggg ttctgtggtc 750

 cagttttcat cagcaaactt ctccttgaca gcagaaacag aagaaaggaa 800

 cttcccccat ggaaatgaac atctgttaaa ttgggcccga aaagagtatg 850

 gagcagttac ttcattcacc gaactcaaga tagcaagaaa catttatatt 900

 aaagtggggg aagatcaagt gttccctcca aagtgcaaca tagggaagaa 950

 ttttctctca ctcaattacc ttgctgagta ccttcaaccc aaagcagcag 1000

 aagggtgtgt gatgtccagc cagccccaga atgaggaagt acacatcatc 1050

 gagctaatca cccccaactc taacccctac agtgctttcc aggtggatat 1100

 aacaattgat ataagacctt ctcaagagga tcttgaagtg gtcaaaaatc 1150

 tcatcctgat cttgaagtgc aaaaagtctg tcaactgggt gatcaaatct 1200

 tttgatgtta agggaagcct gaaaattatt gctcctaaca gtattggctt 1250

 tggaaaagag agtgaaagat ctatgacaat gaccaaatca ataagagatg 1300

 acattccttc aacccaaggg aatctggtga agtgggcttt ggacaatggc 1350

 tatagtccaa taacttcata cacaatggct cctgtggcaa tagtatttca 1400

 tcttcggctt gaaaataatg aggagatggg agatgaggaa gtccacacta 1450

 ttcctcctga gctacggatc ctgctggacc ctggtgccct gcctgccctg 1500

 cagaacccgc ccatccgggg aggggaaggc caaaatggag gccttccgtt 1550

 tcctttccca gatatttcca ggagagtctg gaatgaagag ggagaagatg 1600

 ggctccctcg gccaaaggac cctgtcattc ccagcataca actgtttcct 1650

 ggtctcagag agccagaaga ggtgcaaggg agcgtggata ttgccctgtc 1700

 tgtcaaatgt gacaatgaga agatgatcgt ggctgtagaa aaagattctt 1750

 ttcaggccag tggctactcg gggatggacg tcaccctgtt ggatcctacc 1800

 tgcaaggcca agatgaatgg cacacacttt gttttggagt ctcctctgaa 1850

 tggctgcggt actcggcccc ggtggtcagc ccttgatggt gtggtctact 1900

 ataactccat tgtgatacag gttccagccc ttggggacag tagtggttgg 1950

 ccagatggtt atgaagatct ggagtcaggt gataatggat ttccgggaga 2000

 tatggatgaa ggagatgctt ccctgttcac ccgacctgaa atcgtggtgt 2050

 ttaattgcag ccttcagcag gtgaggaacc ccagcagctt ccaggaacag 2100

 ccccacggaa acatcacctt caacatggag ctatacaaca ctgacctctt 2150

 tttggtgccc tcccagggcg tcttctctgt gccagagaat ggacacgttt 2200

 atgttgaggt atctgttact aaggctgaac aagaactggg atttgccatc 2250

 caaacgtgct ttatctctcc atattcgaac cctgatagga tgtctcatta 2300

 caccattatt gagaatattt gtcctaaaga tgaatctgtg aaattctaca 2350

 gtcccaagag agtgcacttc cctatcccgc aagctgacat ggataagaag 2400

 cgattcagct ttgtcttcaa gcctgtcttc aacacctcac tgctctttct 2450

 acagtgtgag ctgacgctgt gtacgaagat ggagaagcac ccccagaagt 2500

 tgcctaagtg tgtgcctcct gacgaagcct gcacctcgct ggacgcctcg 2550

 ataatctggg ccatgatgca gaataagaag acgttcacca agccccttgc 2600

 tgtgatccac catgaagcag aatctaaaga aaaaggtcca agcatgaagg 2650

 aaccaaatcc aatttctcca ccaattttcc atggtctgga caccctaacc 2700

 gtgatgggca ttgcgtttgc agcctttgtg atcggagcac tcctgacggg 2750

 ggccttgtgg tacatctatt ctcacacagg ggagacagca ggaaggcagc 2800

 aagtccccac ctccccgcca gcctcggaaa acagcagtgc tgcccacagc 2850

 atcggcagca cgcagagcac gccttgctcc agcagcagca cggcctagcc 2900

 caacccaggc ccaacccggc ccaacccagc ccagcccagc tcagctcagc 2950

 tactccaagg gcaggaccaa tggctgagcc tcgtgtccag actcagaggg 3000

 ctggattttg gttcccttgt aaagacagag tgaatttcag tataaagatc 3050

 acccgttgta ttcaccccac acccagggct agtataaaca tgaccctggg 3100

 cttctgtacc acactagaat tcatgtgaga aagctaaaat ggtggtcttc 3150

 tccaccagcc cctcacaggc ttgggggttt tctatgtgaa acacatgcca 3200

 gtttttaaaa tgctgctttg tccaggtgag aacatccata atttggggcc 3250

 ctgagtttta cccagactca aggagttggt aaagggttaa tagccagata 3300

 gtagaaccag tgaggagatg cggccaaaga ttctttatat ctgaaccaag 3350

 atgtaaaaca agaaatgctt tgaggctttc taagcgatcc tcctgtctaa 3400

 tttgcacctt tgtctggatg cactcttctg accttgctgc cacaacctgt 3450

 ggggtctgat gtgtcccaag atgggtgctg ccctcaggga ctgcaccctg 3500

 acaagtgtta aggcaacatt ccttgcttgt gccctgggcc aaaaccaatg 3550

 ctgatgacct tatcagcttc ctgtttcttc ccatactgca tacaccactg 3600

 caaaatgtct taatgcaaat tttgtatttc ttacaggcct acagaaattg 3650

 aaaatgacca aaatcaggaa ccacagattt gtgcccattc ctaatatttt 3700

 gttctgcaaa ttaatgtata atttgaggtg aaattcagtt ataaagtcaa 3750

 ggacgaattt gcacagtgat atatttctat gtgtatgcaa gtacaagtat 3800

 ataatatgtc acctggcaca ttcattttct cagttgaaga agagaaaatt 3850

 tgaaaatgtc cttatgcttt tagagttgca acttaagtat atttggtagg 3900

 gtgagtgttt ccactcaaaa tatgtcaact taaaaaaaaa taggcccttt 3950

 cataaaaacc aaactgtagc aagatgcaaa tgcatggcaa atctgtcggt 4000

 ctccagttgg ttatctgaat agtgtcacca attccaccaa gacagtgctg 4050

 agattggaaa gggcactcat ttggattgcc ttacttctct tgccttaaat 4100

 atatcccata tatttaatat gtcaaaaagg gcttgaggtg aatttcatta 4150

 aatggaataa tatgatgcca ctttgcagct aaaataagct cagtgatacc 4200

 tccttgtt 4208

<210> 5542
<211> 849
<212> PRT
<213> Homo sapien

<400> 5542
 Met Thr Ser His Tyr Val Ile Ala Ile Phe Ala Leu Met Ser Phe
   1               5                  10                  15

 Cys Leu Ala Thr Ala Gly Pro Glu Pro Gly Ala Leu Cys Glu Leu
                  20                  25                  30

 Ser Pro Val Ser Ala Ser His Pro Val Gln Ala Leu Met Glu Ser
                  35                  40                  45

 Phe Thr Val Leu Ser Gly Cys Ala Ser Arg Gly Thr Thr Gly Leu
                  50                  55                  60

 Pro Gln Glu Val His Val Leu Asn Leu Ala Leu Arg Gln Gly Pro
                  65                  70                  75

 Gly Gln Leu Gln Arg Glu Val Thr Leu His Leu Asn Pro Ile Ser
                  80                  85                  90

 Ser Val His Ile His His Lys Ser Val Val Phe Leu Leu Asn Ser
                  95                 100                 105

 Pro His Pro Leu Val Trp His Leu Lys Thr Glu Arg Leu Ala Thr
                 110                 115                 120

 Gly Val Ser Arg Leu Phe Leu Val Ser Glu Gly Ser Val Val Gln
                 125                 130                 135

 Phe Ser Ser Ala Asn Phe Ser Leu Thr Ala Glu Thr Glu Glu Arg
                 140                 145                 150

 Asn Phe Pro His Gly Asn Glu His Leu Leu Asn Trp Ala Arg Lys
                 155                 160                 165

 Glu Tyr Gly Ala Val Thr Ser Phe Thr Glu Leu Lys Ile Ala Arg
                 170                 175                 180

 Asn Ile Tyr Ile Lys Val Gly Glu Asp Gln Val Phe Pro Pro Lys
                 185                 190                 195

 Cys Asn Ile Gly Lys Asn Phe Leu Ser Leu Asn Tyr Leu Ala Glu
                 200                 205                 210

 Tyr Leu Gln Pro Lys Ala Ala Glu Gly Cys Val Met Ser Ser Gln
                 215                 220                 225

 Pro Gln Asn Glu Glu Val His Ile Ile Glu Leu Ile Thr Pro Asn
                 230                 235                 240

 Ser Asn Pro Tyr Ser Ala Phe Gln Val Asp Ile Thr Ile Asp Ile
                 245                 250                 255

 Arg Pro Ser Gln Glu Asp Leu Glu Val Val Lys Asn Leu Ile Leu
                 260                 265                 270

 Ile Leu Lys Cys Lys Lys Ser Val Asn Trp Val Ile Lys Ser Phe
                 275                 280                 285

 Asp Val Lys Gly Ser Leu Lys Ile Ile Ala Pro Asn Ser Ile Gly
                 290                 295                 300

 Phe Gly Lys Glu Ser Glu Arg Ser Met Thr Met Thr Lys Ser Ile
                 305                 310                 315

 Arg Asp Asp Ile Pro Ser Thr Gln Gly Asn Leu Val Lys Trp Ala
                 320                 325                 330

 Leu Asp Asn Gly Tyr Ser Pro Ile Thr Ser Tyr Thr Met Ala Pro
                 335                 340                 345

 Val Ala Ile Val Phe His Leu Arg Leu Glu Asn Asn Glu Glu Met
                 350                 355                 360

 Gly Asp Glu Glu Val His Thr Ile Pro Pro Glu Leu Arg Ile Leu
                 365                 370                 375

 Leu Asp Pro Gly Ala Leu Pro Ala Leu Gln Asn Pro Pro Ile Arg
                 380                 385                 390

 Gly Gly Glu Gly Gln Asn Gly Gly Leu Pro Phe Pro Phe Pro Asp
                 395                 400                 405

 Ile Ser Arg Arg Val Trp Asn Glu Glu Gly Glu Asp Gly Leu Pro
                 410                 415                 420

 Arg Pro Lys Asp Pro Val Ile Pro Ser Ile Gln Leu Phe Pro Gly
                 425                 430                 435

 Leu Arg Glu Pro Glu Glu Val Gln Gly Ser Val Asp Ile Ala Leu
                 440                 445                 450

 Ser Val Lys Cys Asp Asn Glu Lys Met Ile Val Ala Val Glu Lys
                 455                 460                 465

 Asp Ser Phe Gln Ala Ser Gly Tyr Ser Gly Met Asp Val Thr Leu
                 470                 475                 480

 Leu Asp Pro Thr Cys Lys Ala Lys Met Asn Gly Thr His Phe Val
                 485                 490                 495

 Leu Glu Ser Pro Leu Asn Gly Cys Gly Thr Arg Pro Arg Trp Ser
                 500                 505                 510

 Ala Leu Asp Gly Val Val Tyr Tyr Asn Ser Ile Val Ile Gln Val
                 515                 520                 525

 Pro Ala Leu Gly Asp Ser Ser Gly Trp Pro Asp Gly Tyr Glu Asp
                 530                 535                 540

 Leu Glu Ser Gly Asp Asn Gly Phe Pro Gly Asp Met Asp Glu Gly
                 545                 550                 555

 Asp Ala Ser Leu Phe Thr Arg Pro Glu Ile Val Val Phe Asn Cys
                 560                 565                 570

 Ser Leu Gln Gln Val Arg Asn Pro Ser Ser Phe Gln Glu Gln Pro
                 575                 580                 585

 His Gly Asn Ile Thr Phe Asn Met Glu Leu Tyr Asn Thr Asp Leu
                 590                 595                 600

 Phe Leu Val Pro Ser Gln Gly Val Phe Ser Val Pro Glu Asn Gly
                 605                 610                 615

 His Val Tyr Val Glu Val Ser Val Thr Lys Ala Glu Gln Glu Leu
                 620                 625                 630

 Gly Phe Ala Ile Gln Thr Cys Phe Ile Ser Pro Tyr Ser Asn Pro
                 635                 640                 645

 Asp Arg Met Ser His Tyr Thr Ile Ile Glu Asn Ile Cys Pro Lys
                 650                 655                 660

 Asp Glu Ser Val Lys Phe Tyr Ser Pro Lys Arg Val His Phe Pro
                 665                 670                 675

 Ile Pro Gln Ala Asp Met Asp Lys Lys Arg Phe Ser Phe Val Phe
                 680                 685                 690

 Lys Pro Val Phe Asn Thr Ser Leu Leu Phe Leu Gln Cys Glu Leu
                 695                 700                 705

 Thr Leu Cys Thr Lys Met Glu Lys His Pro Gln Lys Leu Pro Lys
                 710                 715                 720

 Cys Val Pro Pro Asp Glu Ala Cys Thr Ser Leu Asp Ala Ser Ile
                 725                 730                 735

 Ile Trp Ala Met Met Gln Asn Lys Lys Thr Phe Thr Lys Pro Leu
                 740                 745                 750

 Ala Val Ile His His Glu Ala Glu Ser Lys Glu Lys Gly Pro Ser
                 755                 760                 765

 Met Lys Glu Pro Asn Pro Ile Ser Pro Pro Ile Phe His Gly Leu
                 770                 775                 780

 Asp Thr Leu Thr Val Met Gly Ile Ala Phe Ala Ala Phe Val Ile
                 785                 790                 795

 Gly Ala Leu Leu Thr Gly Ala Leu Trp Tyr Ile Tyr Ser His Thr
                 800                 805                 810

 Gly Glu Thr Ala Gly Arg Gln Gln Val Pro Thr Ser Pro Pro Ala
                 815                 820                 825

 Ser Glu Asn Ser Ser Ala Ala His Ser Ile Gly Ser Thr Gln Ser
                 830                 835                 840

 Thr Pro Cys Ser Ser Ser Ser Thr Ala
                 845

<210> 5543
<211> 501
<212> DNA
<213> Homo sapien

<400> 5543
 gaattcgctt tggatccatt tccatcggtc cttacagccg ctcgtcagac 50

 tccagcagcc aagatggtga agcagatcga gagcaagact gcttttcagg 100

 aagccttgga cgctgcaggt gataaacttg tagtagttga cttctcagcc 150

 acgtggtgtg ggccttgcaa aatgatcaac cctttctttc attccctctc 200

 tgaaaagtat tccaacgtga tattccttga agtagatgtg gatgactgtc 250

 aggatgttgc ttcagagtgt gaagtcaaat gcacgccaac attccagttt 300

 tttaagaagg gacaaaaggt gggtgaattt tctggagcca ataaggaaaa 350

 gcttgaagcc accattaatg aattagtcta atcatgtttt ctgaaaacat 400

 aaccagccat tggctattta aacttgtatt tttttattta caaaatataa 450

 atatgaagac ataaccagtt gccatctgcg tgacaataaa cattatgcta 500

 a 501

<210> 5544
<211> 105
<212> PRT
<213> Homo sapien

<400> 5544
 Met Val Lys Gln Ile Glu Ser Lys Thr Ala Phe Gln Glu Ala Leu
   1               5                  10                  15

 Asp Ala Ala Gly Asp Lys Leu Val Val Val Asp Phe Ser Ala Thr
                  20                  25                  30

 Trp Cys Gly Pro Cys Lys Met Ile Asn Pro Phe Phe His Ser Leu
                  35                  40                  45

 Ser Glu Lys Tyr Ser Asn Val Ile Phe Leu Glu Val Asp Val Asp
                  50                  55                  60

 Asp Cys Gln Asp Val Ala Ser Glu Cys Glu Val Lys Cys Thr Pro
                  65                  70                  75

 Thr Phe Gln Phe Phe Lys Lys Gly Gln Lys Val Gly Glu Phe Ser
                  80                  85                  90

 Gly Ala Asn Lys Glu Lys Leu Glu Ala Thr Ile Asn Glu Leu Val
                  95                 100                 105

<210> 5545
<211> 1404
<212> DNA
<213> Homo sapien

<400> 5545
 gctgcagctg cagcagctgg agggcgaagt gaaggagaca ccgttccgcc 50

 cgcggcctcg ccatggcgac ccacggacag acttgcgcgc gtccaatgtg 100

 tattcctcca tcatatgctg accttggcaa agttgccaga gatattttca 150

 acaaaggatt tggttttggg ttggtgaaac tggatgtgaa aacaaagtct 200

 tgcagtggcg tggaattttc aacgtccggt tcatctaata cagacactgg 250

 taaagttact gggaccttgg agaccaaata caagtggtgt gagtatggtc 300

 tgactttcac agaaaagtgg aacactgata acactctggg aacagaaatc 350

 gcaattgaag accagatttg tcaaggtttg aaactgacat ttgatactac 400

 cttctcacca aacacaggaa agaaaagtgg taaaatcaag tcttcttaca 450

 agagggagtg tataaacctt ggttgtgatg ttgactttga ttttgctgga 500

 cctgcaatcc atggttcagc tgtctttggt tatgagggct ggcttgctgg 550

 ctaccagatg acctttgaca gtgccaaatc aaagctgaca aggaataact 600

 ttgcagtggg ctacaggact ggggacttcc agctacacac taatgtcaat 650

 gatgggacag aatttggagg atcaatttat cagaaagttt gtgaagatct 700

 tgacacttca gtaaaccttg cttggacatc aggtaccaac tgcactcgtt 750

 ttggcattgc agctaaatat cagttggatc ccactgcttc catttctgca 800

 aaagtcaaca actctagctt aattggagta ggctatactc agactctgag 850

 gcctggtgtg aagcttacac tctctgctct ggtagatggg aagagcatta 900

 atgctggagg ccacaaggtt gggctcgccc tggagttgga ggcttaatcc 950

 agctgaaaga aacctttggg aatggatatc agaagatttg gccttaatat 1000

 atttccattg tgaccagcag caggcttttt tcccccaaga agatgatcaa 1050

 aacaaaggat gatctcaaca agagctgtat tttaagtatt tagacagttc 1100

 tttgttagct ggtttctagt tggttatcta gttaccaatg ctgcagtcct 1150

 gcagtcacct atacattatt taaatgtatt taactgttaa atgcgctacc 1200

 caccaataat gaaatagacc tttatgaaaa ctgtgcaatt gtgtgcatgt 1250

 ttgtttttat gttcctttag aaaacattga ctgttaccat tgaatgagat 1300

 ggatcagtgg atattaagat gaggttacaa attttgttaa gttcagccat 1350

 tattactttt ggtatcccag aacatgacaa attatgaata aaacaagtat 1400

 acat 1404

<210> 5546
<211> 294
<212> PRT
<213> Homo sapien

<400> 5546
 Met Ala Thr His Gly Gln Thr Cys Ala Arg Pro Met Cys Ile Pro
   1               5                  10                  15

 Pro Ser Tyr Ala Asp Leu Gly Lys Val Ala Arg Asp Ile Phe Asn
                  20                  25                  30

 Lys Gly Phe Gly Phe Gly Leu Val Lys Leu Asp Val Lys Thr Lys
                  35                  40                  45

 Ser Cys Ser Gly Val Glu Phe Ser Thr Ser Gly Ser Ser Asn Thr
                  50                  55                  60

 Asp Thr Gly Lys Val Thr Gly Thr Leu Glu Thr Lys Tyr Lys Trp
                  65                  70                  75

 Cys Glu Tyr Gly Leu Thr Phe Thr Glu Lys Trp Asn Thr Asp Asn
                  80                  85                  90

 Thr Leu Gly Thr Glu Ile Ala Ile Glu Asp Gln Ile Cys Gln Gly
                  95                 100                 105

 Leu Lys Leu Thr Phe Asp Thr Thr Phe Ser Pro Asn Thr Gly Lys
                 110                 115                 120

 Lys Ser Gly Lys Ile Lys Ser Ser Tyr Lys Arg Glu Cys Ile Asn
                 125                 130                 135

 Leu Gly Cys Asp Val Asp Phe Asp Phe Ala Gly Pro Ala Ile His
                 140                 145                 150

 Gly Ser Ala Val Phe Gly Tyr Glu Gly Trp Leu Ala Gly Tyr Gln
                 155                 160                 165

 Met Thr Phe Asp Ser Ala Lys Ser Lys Leu Thr Arg Asn Asn Phe
                 170                 175                 180

 Ala Val Gly Tyr Arg Thr Gly Asp Phe Gln Leu His Thr Asn Val
                 185                 190                 195

 Asn Asp Gly Thr Glu Phe Gly Gly Ser Ile Tyr Gln Lys Val Cys
                 200                 205                 210

 Glu Asp Leu Asp Thr Ser Val Asn Leu Ala Trp Thr Ser Gly Thr
                 215                 220                 225

 Asn Cys Thr Arg Phe Gly Ile Ala Ala Lys Tyr Gln Leu Asp Pro
                 230                 235                 240

 Thr Ala Ser Ile Ser Ala Lys Val Asn Asn Ser Ser Leu Ile Gly
                 245                 250                 255

 Val Gly Tyr Thr Gln Thr Leu Arg Pro Gly Val Lys Leu Thr Leu
                 260                 265                 270

 Ser Ala Leu Val Asp Gly Lys Ser Ile Asn Ala Gly Gly His Lys
                 275                 280                 285

 Val Gly Leu Ala Leu Glu Leu Glu Ala
                 290

<210> 5547
<211> 1645
<212> DNA
<213> Homo sapien

<400> 5547
 gtagcaaagt gacgccgagg gcctgagtgc tccagtagcc accgcatctg 50

 gagaaccagc ggttaccatg gaggggatca gtatatacac ttcagataac 100

 tacaccgagg aaatgggctc aggggactat gactccatga aggaaccctg 150

 tttccgtgaa gaaaatgcta atttcaataa aatcttcctg cccaccatct 200

 actccatcat cttcttaact ggcattgtgg gcaatggatt ggtcatcctg 250

 gtcatgggtt accagaagaa actgagaagc atgacggaca agtacaggct 300

 gcacctgtca gtggccgacc tcctctttgt catcacgctt cccttctggg 350

 cagttgatgc cgtggcaaac tggtactttg ggaacttcct atgcaaggca 400

 gtccatgtca tctacacagt caacctctac agcagtgtcc tcatcctggc 450

 cttcatcagt ctggaccgct acctggccat cgtccacgcc accaacagtc 500

 agaggccaag gaagctgttg gctgaaaagg tggtctatgt tggcgtctgg 550

 atccctgccc tcctgctgac tattcccgac ttcatctttg ccaacgtcag 600

 tgaggcagat gacagatata tctgtgaccg cttctacccc aatgacttgt 650

 gggtggttgt gttccagttt cagcacatca tggttggcct tatcctgcct 700

 ggtattgtca tcctgtcctg ctattgcatt atcatctcca agctgtcaca 750

 ctccaagggc caccagaagc gcaaggccct caagaccaca gtcatcctca 800

 tcctggcttt cttcgcctgt tggctgcctt actacattgg gatcagcatc 850

 gactccttca tcctcctgga aatcatcaag caagggtgtg agtttgagaa 900

 cactgtgcac aagtggattt ccatcaccga ggccctagct ttcttccact 950

 gttgtctgaa ccccatcctc tatgctttcc ttggagccaa atttaaaacc 1000

 tctgcccagc acgcactcac ctctgtgagc agagggtcca gcctcaagat 1050

 cctctccaaa ggaaagcgag gtggacattc atctgtttcc actgagtctg 1100

 agtcttcaag ttttcactcc agctaacaca gatgtaaaag actttttttt 1150

 atacgataaa taactttttt ttaagttaca catttttcag atataaaaga 1200

 ctgaccaata ttgtacagtt tttattgctt gttggatttt tgtcttgtgt 1250

 ttctttagtt tttgtgaagt ttaattgact tatttatata aatttttttt 1300

 gtttcatatt gatgtgtgtc taggcaggac ctgtggccaa gttcttagtt 1350

 gctgtatgtc tcgtggtagg actgtagaaa agggaactga acattccaga 1400

 gcgtgtagtg aatcacgtaa agctagaaat gatccccagc tgtttatgca 1450

 tagataatct ctccattccc gtggaacgtt tttcctgttc ttaagacgtg 1500

 attttgctgt agaagatggc acttataacc aaagcccaaa gtggtataga 1550

 aatgctggtt tttcagtttt caggagtggg ttgatttcag cacctacagt 1600

 gtacagtctt gtattaagtt gttaataaaa gtacatgtta aactt 1645

<210> 5548
<211> 352
<212> PRT
<213> Homo sapien

<400> 5548
 Met Glu Gly Ile Ser Ile Tyr Thr Ser Asp Asn Tyr Thr Glu Glu
   1               5                  10                  15

 Met Gly Ser Gly Asp Tyr Asp Ser Met Lys Glu Pro Cys Phe Arg
                  20                  25                  30

 Glu Glu Asn Ala Asn Phe Asn Lys Ile Phe Leu Pro Thr Ile Tyr
                  35                  40                  45

 Ser Ile Ile Phe Leu Thr Gly Ile Val Gly Asn Gly Leu Val Ile
                  50                  55                  60

 Leu Val Met Gly Tyr Gln Lys Lys Leu Arg Ser Met Thr Asp Lys
                  65                  70                  75

 Tyr Arg Leu His Leu Ser Val Ala Asp Leu Leu Phe Val Ile Thr
                  80                  85                  90

 Leu Pro Phe Trp Ala Val Asp Ala Val Ala Asn Trp Tyr Phe Gly
                  95                 100                 105

 Asn Phe Leu Cys Lys Ala Val His Val Ile Tyr Thr Val Asn Leu
                 110                 115                 120

 Tyr Ser Ser Val Leu Ile Leu Ala Phe Ile Ser Leu Asp Arg Tyr
                 125                 130                 135

 Leu Ala Ile Val His Ala Thr Asn Ser Gln Arg Pro Arg Lys Leu
                 140                 145                 150

 Leu Ala Glu Lys Val Val Tyr Val Gly Val Trp Ile Pro Ala Leu
                 155                 160                 165

 Leu Leu Thr Ile Pro Asp Phe Ile Phe Ala Asn Val Ser Glu Ala
                 170                 175                 180

 Asp Asp Arg Tyr Ile Cys Asp Arg Phe Tyr Pro Asn Asp Leu Trp
                 185                 190                 195

 Val Val Val Phe Gln Phe Gln His Ile Met Val Gly Leu Ile Leu
                 200                 205                 210

 Pro Gly Ile Val Ile Leu Ser Cys Tyr Cys Ile Ile Ile Ser Lys
                 215                 220                 225

 Leu Ser His Ser Lys Gly His Gln Lys Arg Lys Ala Leu Lys Thr
                 230                 235                 240

 Thr Val Ile Leu Ile Leu Ala Phe Phe Ala Cys Trp Leu Pro Tyr
                 245                 250                 255

 Tyr Ile Gly Ile Ser Ile Asp Ser Phe Ile Leu Leu Glu Ile Ile
                 260                 265                 270

 Lys Gln Gly Cys Glu Phe Glu Asn Thr Val His Lys Trp Ile Ser
                 275                 280                 285

 Ile Thr Glu Ala Leu Ala Phe Phe His Cys Cys Leu Asn Pro Ile
                 290                 295                 300

 Leu Tyr Ala Phe Leu Gly Ala Lys Phe Lys Thr Ser Ala Gln His
                 305                 310                 315

 Ala Leu Thr Ser Val Ser Arg Gly Ser Ser Leu Lys Ile Leu Ser
                 320                 325                 330

 Lys Gly Lys Arg Gly Gly His Ser Ser Val Ser Thr Glu Ser Glu
                 335                 340                 345

 Ser Ser Ser Phe His Ser Ser
                 350

<210> 5549
<211> 1932
<212> DNA
<213> Homo sapien

<400> 5549
 ggcacgaggc ctcgtgccgc cgggctcttg gtacctcagc gcgagcgcca 50

 ggcgtccggc cgccgtggct atgttcgtgt ccgatttccg caaagagttc 100

 tacgaggtgg tccagagcca gagggtcctt ctcttcgtgg cctcggacgt 150

 ggatgctctg tgtgcgtgca agatccttca ggccttgttc cagtgtgacc 200

 acgtgcaata tacgctggtt ccagtttctg ggtggcaaga acttgaaact 250

 gcatttcttg agcataaaga acagtttcat tattttattc tcataaactg 300

 tggagctaat gtagacctat tggatattct tcaacctgat gaagacacta 350

 tattctttgt gtgtgacacc cataggccag tcaatgtcgt caatgtatac 400

 aacgataccc agatcaaatt actcattaaa caagatgatg accttgaagt 450

 tcccgcctat gaagacatct tcagggatga agaggaggat gaagagcatt 500

 caggaaatga cagtgatggg tcagagcctt ctgagaagcg cacacggtta 550

 gaagaggaga tagtggagca aaccatgcgg aggaggcagc ggcgagagtg 600

 ggaggcccgg agaagagaca tcctctttga ctacgagcag tatgaatatc 650

 atgggacatc gtcagccatg gtgatgtttg agctggcttg gatgctgtcc 700

 aaggacctga atgacatgct gtggtgggcc atcgttggac taacagacca 750

 gtgggtgcaa gacaagatca ctcaaatgaa atacgtgact gatgttggtg 800

 tcctgcagcg ccacgtttcc cgccacaacc accggaacga ggatgaggag 850

 aacacactct ccgtggactg cacacggatc tcctttgagt atgacctccg 900

 cctggtgctc taccagcact ggtccctcca tgacagcctg tgcaacacca 950

 gctataccgc agccaggttc aagctgtggt ctgtgcatgg acagaagcgg 1000

 ctccaggagt tccttgcaga catgggtctt cccctgaagc aggtgaagca 1050

 gaagttccag gccatggaca tctccttgaa ggagaatttg cgggaaatga 1100

 ttgaagagtc tgcaaataaa tttgggatga aggacatgcg cgtgcagact 1150

 ttcagcattc attttgggtt caagcacaag tttctggcca gcgacgtggt 1200

 ctttgccacc atgtctttga tggagagccc cgagaaggat ggctcaggga 1250

 cagatcactt catccaggct ctggacagcc tctccaggag taacctggac 1300

 aagctgtacc atggcctgga actcgccaag aagcagctgc gagccaccca 1350

 gcagaccatt gccagctgcc tttgcaccaa cctcgtcatc tcccaggggc 1400

 ctttcctgta ctgctctctc atggagggca ctccagatgt catgctgttc 1450

 tctaggccgg catccctaag cctgctcagc aaacacctgc tcaagtcctt 1500

 tgtgtgttcg acaaagaacc ggcgctgcaa actgctgccc ctggtgatgg 1550

 ctgcccccct gagcatggag catggcacag tgaccgtggt gggcatcccc 1600

 ccagagaccg acagctcgga caggaagaac ttttttggga gggcgtttga 1650

 gaaggcagcg gaaagcacca gctcccggat gctgcacaac cattttgacc 1700

 tctcagtaat tgagctgaaa gctgaggatc ggagcaagtt tctggacgca 1750

 cttatttccc tcctgtccta ggaatttgat tcttccagaa tgaccttctt 1800

 atttatgtaa ctggctttca tttagattgt aagttatgga catgatttga 1850

 gatgtagaag ccatttttta ttaaataaaa tgcttatttt aggctccgtc 1900

 cccaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1932

<210> 5550
<211> 566
<212> PRT
<213> Homo sapien

<400> 5550
 Met Phe Val Ser Asp Phe Arg Lys Glu Phe Tyr Glu Val Val Gln
   1               5                  10                  15

 Ser Gln Arg Val Leu Leu Phe Val Ala Ser Asp Val Asp Ala Leu
                  20                  25                  30

 Cys Ala Cys Lys Ile Leu Gln Ala Leu Phe Gln Cys Asp His Val
                  35                  40                  45

 Gln Tyr Thr Leu Val Pro Val Ser Gly Trp Gln Glu Leu Glu Thr
                  50                  55                  60

 Ala Phe Leu Glu His Lys Glu Gln Phe His Tyr Phe Ile Leu Ile
                  65                  70                  75

 Asn Cys Gly Ala Asn Val Asp Leu Leu Asp Ile Leu Gln Pro Asp
                  80                  85                  90

 Glu Asp Thr Ile Phe Phe Val Cys Asp Thr His Arg Pro Val Asn
                  95                 100                 105

 Val Val Asn Val Tyr Asn Asp Thr Gln Ile Lys Leu Leu Ile Lys
                 110                 115                 120

 Gln Asp Asp Asp Leu Glu Val Pro Ala Tyr Glu Asp Ile Phe Arg
                 125                 130                 135

 Asp Glu Glu Glu Asp Glu Glu His Ser Gly Asn Asp Ser Asp Gly
                 140                 145                 150

 Ser Glu Pro Ser Glu Lys Arg Thr Arg Leu Glu Glu Glu Ile Val
                 155                 160                 165

 Glu Gln Thr Met Arg Arg Arg Gln Arg Arg Glu Trp Glu Ala Arg
                 170                 175                 180

 Arg Arg Asp Ile Leu Phe Asp Tyr Glu Gln Tyr Glu Tyr His Gly
                 185                 190                 195

 Thr Ser Ser Ala Met Val Met Phe Glu Leu Ala Trp Met Leu Ser
                 200                 205                 210

 Lys Asp Leu Asn Asp Met Leu Trp Trp Ala Ile Val Gly Leu Thr
                 215                 220                 225

 Asp Gln Trp Val Gln Asp Lys Ile Thr Gln Met Lys Tyr Val Thr
                 230                 235                 240

 Asp Val Gly Val Leu Gln Arg His Val Ser Arg His Asn His Arg
                 245                 250                 255

 Asn Glu Asp Glu Glu Asn Thr Leu Ser Val Asp Cys Thr Arg Ile
                 260                 265                 270

 Ser Phe Glu Tyr Asp Leu Arg Leu Val Leu Tyr Gln His Trp Ser
                 275                 280                 285

 Leu His Asp Ser Leu Cys Asn Thr Ser Tyr Thr Ala Ala Arg Phe
                 290                 295                 300

 Lys Leu Trp Ser Val His Gly Gln Lys Arg Leu Gln Glu Phe Leu
                 305                 310                 315

 Ala Asp Met Gly Leu Pro Leu Lys Gln Val Lys Gln Lys Phe Gln
                 320                 325                 330

 Ala Met Asp Ile Ser Leu Lys Glu Asn Leu Arg Glu Met Ile Glu
                 335                 340                 345

 Glu Ser Ala Asn Lys Phe Gly Met Lys Asp Met Arg Val Gln Thr
                 350                 355                 360

 Phe Ser Ile His Phe Gly Phe Lys His Lys Phe Leu Ala Ser Asp
                 365                 370                 375

 Val Val Phe Ala Thr Met Ser Leu Met Glu Ser Pro Glu Lys Asp
                 380                 385                 390

 Gly Ser Gly Thr Asp His Phe Ile Gln Ala Leu Asp Ser Leu Ser
                 395                 400                 405

 Arg Ser Asn Leu Asp Lys Leu Tyr His Gly Leu Glu Leu Ala Lys
                 410                 415                 420

 Lys Gln Leu Arg Ala Thr Gln Gln Thr Ile Ala Ser Cys Leu Cys
                 425                 430                 435

 Thr Asn Leu Val Ile Ser Gln Gly Pro Phe Leu Tyr Cys Ser Leu
                 440                 445                 450

 Met Glu Gly Thr Pro Asp Val Met Leu Phe Ser Arg Pro Ala Ser
                 455                 460                 465

 Leu Ser Leu Leu Ser Lys His Leu Leu Lys Ser Phe Val Cys Ser
                 470                 475                 480

 Thr Lys Asn Arg Arg Cys Lys Leu Leu Pro Leu Val Met Ala Ala
                 485                 490                 495

 Pro Leu Ser Met Glu His Gly Thr Val Thr Val Val Gly Ile Pro
                 500                 505                 510

 Pro Glu Thr Asp Ser Ser Asp Arg Lys Asn Phe Phe Gly Arg Ala
                 515                 520                 525

 Phe Glu Lys Ala Ala Glu Ser Thr Ser Ser Arg Met Leu His Asn
                 530                 535                 540

 His Phe Asp Leu Ser Val Ile Glu Leu Lys Ala Glu Asp Arg Ser
                 545                 550                 555

 Lys Phe Leu Asp Ala Leu Ile Ser Leu Leu Ser
                 560                 565

<210> 5551
<211> 3342
<212> DNA
<213> Homo sapien

<400> 5551
 gcagctccag tcccggacgc aaccccggag ccgtctcagg tccctggggg 50

 gaacggtggg ttagacgggg acgggaaggg acagcggcct tcgaccgccc 100

 cccgagtaat tgacccagga ctcattttca ggaaagcctg aaaatgagta 150

 aaatagtgaa atgaggaatt tgaacatttt atctttggat ggggatcttc 200

 tgaggatgca aagagtgatt catccaagcc atgtggtaaa atcaggaatt 250

 tgaagaaaat ggagatgttt acatttttgt tgacgtgtat ttttctaccc 300

 ctcctaagag ggcacagtct cttcacctgt gaaccaatta ctgttcccag 350

 atgtatgaaa atggcctaca acatgacgtt tttccctaat ctgatgggtc 400

 attatgacca gagtattgcc gcggtggaaa tggagcattt tcttcctctc 450

 gcaaatctgg aatgttcacc aaacattgaa actttcctct gcaaagcatt 500

 tgtaccaacc tgcatagaac aaattcatgt ggttccacct tgtcgtaaac 550

 tttgtgagaa agtatattct gattgcaaaa aattaattga cacttttggg 600

 atccgatggc ctgaggagct tgaatgtgac agattacaat actgtgatga 650

 gactgttcct gtaacttttg atccacacac agaatttctt ggtcctcaga 700

 agaaaacaga acaagtccaa agagacattg gattttggtg tccaaggcat 750

 cttaagactt ctgggggaca aggatataag tttctgggaa ttgaccagtg 800

 tgcgcctcca tgccccaaca tgtattttaa aagtgatgag ctagagtttg 850

 caaaaagttt tattggaaca gtttcaatat tttgtctttg tgcaactctg 900

 ttcacattcc ttactttttt aattgatgtt agaagattca gatacccaga 950

 gagaccaatt atatattact ctgtctgtta cagcattgta tctcttatgt 1000

 acttcattgg atttttgctg ggcgatagca cagcctgcaa taaggcagat 1050

 gagaagctag aacttggtga cactgttgtc ctaggctctc aaaataaggc 1100

 ttgcaccgtt ttgttcatgc ttttgtattt tttcacaatg gctggcactg 1150

 tgtggtgggt gattcttacc attacttggt tcttagctgc aggaagaaaa 1200

 tggagttgtg aagccatcga gcaaaaagca gtgtggtttc atgctgttgc 1250

 atggggaaca ccaggtttcc tgactgttat gcttcttgct ctgaacaaag 1300

 ttgaaggaga caacattagt ggagtttgct ttgttggcct ttatgacctg 1350

 gatgcttctc gctactttgt actcttgcca ctgtgccttt gtgtgtttgt 1400

 tgggctctct cttcttttag ctggcattat ttccttaaat catgttcgac 1450

 aagtcataca acatgatggc cggaaccaag aaaaactaaa gaaatttatg 1500

 attcgaattg gagtcttcag cggcttgtat cttgtgccat tagtgacact 1550

 tctcggatgt tacgtctatg agcaagtgaa caggattacc tgggagataa 1600

 cttgggtctc tgatcattgt cgtcagtacc atatcccatg tccttatcag 1650

 gcaaaagcaa aagctcgacc agaattggct ttatttatga taaaatacct 1700

 gatgacatta attgttggca tctctgctgt cttctgggtt ggaagcaaaa 1750

 agacatgcac agaatgggct gggtttttta aacgaaatcg caagagagat 1800

 ccaatcagtg aaagtcgaag agtactacag gaatcatgtg agtttttctt 1850

 aaagcacaat tctaaagtta aacacaaaaa gaagcactat aaaccaagtt 1900

 cacacaagct gaaggtcatt tccaaatcca tgggaaccag cacaggagct 1950

 acagcaaatc atggcacttc tgcagtagca attactagcc atgattacct 2000

 aggacaagaa actttgacag aaatccaaac ctcaccagaa acatcaatga 2050

 gagaggtgaa agcggacgga gctagcaccc ccaggttaag agaacaggac 2100

 tgtggtgaac ctgcctcgcc agcagcatcc atctccagac tctctgggga 2150

 acaggtcgac gggaagggcc aggcaggcag tgtatctgaa agtgcgcgga 2200

 gtgaaggaag gattagtcca aagagtgata ttactgacac tggcctggca 2250

 cagagcaaca atttgcaggt ccccagttct tcagaaccaa gcagcctcaa 2300

 aggttccaca tctctgcttg ttcacccagt ttcaggagtg agaaaagagc 2350

 agggaggtgg ttgtcattca gatacttgaa gaacattttc tctcgttact 2400

 cagaagcaaa tttgtgttac actggaagtg acctatgcac tgttttgtaa 2450

 gaatcactgt tacgttcttc ttttgcactt aaagttgcat tgcctactgt 2500

 tatactggaa aaaatagagt tcaagaataa tatgactcat ttcacacaaa 2550

 ggttaatgac aacaatatac ctgaaaacag aaatgtgcag gttaataata 2600

 tttttttaat agtgtgggag gacagagtta gaggaatctt ccttttctat 2650

 ttatgaagat tctactcttg gtaagagtat tttaagatgt actatgctat 2700

 tttacctttt tgatataaaa tcaagatatt tctttgctga agtatttaaa 2750

 tcttatcctt gtatcttttt atacatattt gaaaataagc ttatatgtat 2800

 ttgaactttt ttgaaatcct attcaagtat ttttatcatg ctattgtgat 2850

 attttagcac tttggtagct tttacactga atttctaaga aaattgtaaa 2900

 atagtcttct tttatactgt aaaaaaagat ataccaaaaa gtcttataat 2950

 aggaatttaa ctttaaaaac ccacttattg ataccttacc atctaaaatg 3000

 tgtgattttt atagtctcgt tttaggaatt tcacagatct aaattatgta 3050

 actgaaataa ggtgcttact caaagagtgt ccactattga ttgtattatg 3100

 ctgctcactg atccttctgc atatttaaaa taaaatgtcc taaagggtta 3150

 gtagacaaaa tgttagtctt ttgtatatta ggccaagtgc aattgacttc 3200

 ccttttttaa tgtttcatga ccacccattg attgtattat aaccacttac 3250

 agttgcttat attttttgtt ttaacttttg tttcttaaca tttagaatat 3300

 tacattttgt attatacagt acctttctca gacattttgt ag 3342

<210> 5552
<211> 706
<212> PRT
<213> Homo sapien

<400> 5552
 Met Glu Met Phe Thr Phe Leu Leu Thr Cys Ile Phe Leu Pro Leu
   1               5                  10                  15

 Leu Arg Gly His Ser Leu Phe Thr Cys Glu Pro Ile Thr Val Pro
                  20                  25                  30

 Arg Cys Met Lys Met Ala Tyr Asn Met Thr Phe Phe Pro Asn Leu
                  35                  40                  45

 Met Gly His Tyr Asp Gln Ser Ile Ala Ala Val Glu Met Glu His
                  50                  55                  60

 Phe Leu Pro Leu Ala Asn Leu Glu Cys Ser Pro Asn Ile Glu Thr
                  65                  70                  75

 Phe Leu Cys Lys Ala Phe Val Pro Thr Cys Ile Glu Gln Ile His
                  80                  85                  90

 Val Val Pro Pro Cys Arg Lys Leu Cys Glu Lys Val Tyr Ser Asp
                  95                 100                 105

 Cys Lys Lys Leu Ile Asp Thr Phe Gly Ile Arg Trp Pro Glu Glu
                 110                 115                 120

 Leu Glu Cys Asp Arg Leu Gln Tyr Cys Asp Glu Thr Val Pro Val
                 125                 130                 135

 Thr Phe Asp Pro His Thr Glu Phe Leu Gly Pro Gln Lys Lys Thr
                 140                 145                 150

 Glu Gln Val Gln Arg Asp Ile Gly Phe Trp Cys Pro Arg His Leu
                 155                 160                 165

 Lys Thr Ser Gly Gly Gln Gly Tyr Lys Phe Leu Gly Ile Asp Gln
                 170                 175                 180

 Cys Ala Pro Pro Cys Pro Asn Met Tyr Phe Lys Ser Asp Glu Leu
                 185                 190                 195

 Glu Phe Ala Lys Ser Phe Ile Gly Thr Val Ser Ile Phe Cys Leu
                 200                 205                 210

 Cys Ala Thr Leu Phe Thr Phe Leu Thr Phe Leu Ile Asp Val Arg
                 215                 220                 225

 Arg Phe Arg Tyr Pro Glu Arg Pro Ile Ile Tyr Tyr Ser Val Cys
                 230                 235                 240

 Tyr Ser Ile Val Ser Leu Met Tyr Phe Ile Gly Phe Leu Leu Gly
                 245                 250                 255

 Asp Ser Thr Ala Cys Asn Lys Ala Asp Glu Lys Leu Glu Leu Gly
                 260                 265                 270

 Asp Thr Val Val Leu Gly Ser Gln Asn Lys Ala Cys Thr Val Leu
                 275                 280                 285

 Phe Met Leu Leu Tyr Phe Phe Thr Met Ala Gly Thr Val Trp Trp
                 290                 295                 300

 Val Ile Leu Thr Ile Thr Trp Phe Leu Ala Ala Gly Arg Lys Trp
                 305                 310                 315

 Ser Cys Glu Ala Ile Glu Gln Lys Ala Val Trp Phe His Ala Val
                 320                 325                 330

 Ala Trp Gly Thr Pro Gly Phe Leu Thr Val Met Leu Leu Ala Leu
                 335                 340                 345

 Asn Lys Val Glu Gly Asp Asn Ile Ser Gly Val Cys Phe Val Gly
                 350                 355                 360

 Leu Tyr Asp Leu Asp Ala Ser Arg Tyr Phe Val Leu Leu Pro Leu
                 365                 370                 375

 Cys Leu Cys Val Phe Val Gly Leu Ser Leu Leu Leu Ala Gly Ile
                 380                 385                 390

 Ile Ser Leu Asn His Val Arg Gln Val Ile Gln His Asp Gly Arg
                 395                 400                 405

 Asn Gln Glu Lys Leu Lys Lys Phe Met Ile Arg Ile Gly Val Phe
                 410                 415                 420

 Ser Gly Leu Tyr Leu Val Pro Leu Val Thr Leu Leu Gly Cys Tyr
                 425                 430                 435

 Val Tyr Glu Gln Val Asn Arg Ile Thr Trp Glu Ile Thr Trp Val
                 440                 445                 450

 Ser Asp His Cys Arg Gln Tyr His Ile Pro Cys Pro Tyr Gln Ala
                 455                 460                 465

 Lys Ala Lys Ala Arg Pro Glu Leu Ala Leu Phe Met Ile Lys Tyr
                 470                 475                 480

 Leu Met Thr Leu Ile Val Gly Ile Ser Ala Val Phe Trp Val Gly
                 485                 490                 495

 Ser Lys Lys Thr Cys Thr Glu Trp Ala Gly Phe Phe Lys Arg Asn
                 500                 505                 510

 Arg Lys Arg Asp Pro Ile Ser Glu Ser Arg Arg Val Leu Gln Glu
                 515                 520                 525

 Ser Cys Glu Phe Phe Leu Lys His Asn Ser Lys Val Lys His Lys
                 530                 535                 540

 Lys Lys His Tyr Lys Pro Ser Ser His Lys Leu Lys Val Ile Ser
                 545                 550                 555

 Lys Ser Met Gly Thr Ser Thr Gly Ala Thr Ala Asn His Gly Thr
                 560                 565                 570

 Ser Ala Val Ala Ile Thr Ser His Asp Tyr Leu Gly Gln Glu Thr
                 575                 580                 585

 Leu Thr Glu Ile Gln Thr Ser Pro Glu Thr Ser Met Arg Glu Val
                 590                 595                 600

 Lys Ala Asp Gly Ala Ser Thr Pro Arg Leu Arg Glu Gln Asp Cys
                 605                 610                 615

 Gly Glu Pro Ala Ser Pro Ala Ala Ser Ile Ser Arg Leu Ser Gly
                 620                 625                 630

 Glu Gln Val Asp Gly Lys Gly Gln Ala Gly Ser Val Ser Glu Ser
                 635                 640                 645

 Ala Arg Ser Glu Gly Arg Ile Ser Pro Lys Ser Asp Ile Thr Asp
                 650                 655                 660

 Thr Gly Leu Ala Gln Ser Asn Asn Leu Gln Val Pro Ser Ser Ser
                 665                 670                 675

 Glu Pro Ser Ser Leu Lys Gly Ser Thr Ser Leu Leu Val His Pro
                 680                 685                 690

 Val Ser Gly Val Arg Lys Glu Gln Gly Gly Gly Cys His Ser Asp
                 695                 700                 705

 Thr


<210> 5553
<211> 647
<212> DNA
<213> Homo sapien

<400> 5553
 gctcactgag caccgtccca gcatccggac accacagcgg cccttcgctc 50

 cacgcagaaa accacacttc tcataccttc actcaacact tccttcccca 100

 aagccagaag atgcacaagg aggaacatga ggtggctgtg ctgggggcac 150

 cccccagcac catccttcca aggtccaccg tgattaacat ccacagcgag 200

 acctccgtgc ccgaccatgt cgtctggtcc ctgttcaaca ccctcttctt 250

 gaactggtgc tgtctgggct tcatagcatt cgcctactcc gtaaagtcta 300

 gggacaggaa gatggttggc gacgtgaccg gggcccaggc ctatgcctcc 350

 accgccaagt gcctgaacat ctgggccctg attctgggca tcctcatgac 400

 cattggattc atcctgttac tggtattcgg ctctgtaaca gtctaccata 450

 ttatgttaca gataatacag gaaaaacggg gttactagta gccgcccata 500

 gcctgcaacc tttgcactcc actgtgcaat gctggccctg cacgctgggg 550

 ctgttgcccc tgcccccttg gtcctgcccc tagatacagc agtttatacc 600

 cacacacctg tctacagtgt cattcaataa agtgcacgtg cttgtga 647

<210> 5554
<211> 125
<212> PRT
<213> Homo sapien

<400> 5554
 Met His Lys Glu Glu His Glu Val Ala Val Leu Gly Ala Pro Pro
   1               5                  10                  15

 Ser Thr Ile Leu Pro Arg Ser Thr Val Ile Asn Ile His Ser Glu
                  20                  25                  30

 Thr Ser Val Pro Asp His Val Val Trp Ser Leu Phe Asn Thr Leu
                  35                  40                  45

 Phe Leu Asn Trp Cys Cys Leu Gly Phe Ile Ala Phe Ala Tyr Ser
                  50                  55                  60

 Val Lys Ser Arg Asp Arg Lys Met Val Gly Asp Val Thr Gly Ala
                  65                  70                  75

 Gln Ala Tyr Ala Ser Thr Ala Lys Cys Leu Asn Ile Trp Ala Leu
                  80                  85                  90

 Ile Leu Gly Ile Leu Met Thr Ile Gly Phe Ile Leu Leu Leu Val
                  95                 100                 105

 Phe Gly Ser Val Thr Val Tyr His Ile Met Leu Gln Ile Ile Gln
                 110                 115                 120

 Glu Lys Arg Gly Tyr
                 125

<210> 5555
<211> 928
<212> DNA
<213> Homo sapien

<400> 5555
 gctgtggccc tggcacctgc ccctgggctg ggacagccca ctgttccatg 50

 ctgcccaaga aggctcagca caggcacaaa ccattgcccg gcactggccc 100

 gtgctgcctg agaaggattg gcacgggcac agaccactgc ccccacctgc 150

 cctgcgccat ctacccaaga aggctcggca cgggcaccaa ccactgcctc 200

 caactgcccc atgctgcctg agaaggcact gcacggccac ccccaactgc 250

 cccgcactgt ccctacccgg gcagccatgc gagcggctgg aactctgctg 300

 gccttctgct gcctggtctt gagcaccact gggggccctt ccccagatac 350

 ttgttcccag gaccttaact cacgtgtgaa gccaggattt cctaaaacaa 400

 taaagaccaa tgacccagga gtcctccaag cagccagata cagtgttgaa 450

 aagttcaaca actgcacgaa cgacatgttc ttgttcaagg agtcccgcat 500

 cacaagggcc ctagttcaga tagtgaaagg cctgaaatat atgctggagg 550

 tggaaattgg cagaactacc tgcaagaaaa accagcacct gcgtctggat 600

 gactgtgact tccaaaccaa ccacaccttg aagcagactc tgagctgcta 650

 ctctgaagtc tgggtcgtgc cctggctcca gcacttcgag gtgcctgttc 700

 tccgttgtca ctgacccccg cctcttcagc aagaccacag ccatgacaaa 750

 caccaggatg catgctcctt gtcccctccc acccgcctca tgacccagcc 800

 tcacagaccc tctcaggcct ctgacgagtg agcgggtgaa gtgccactgg 850

 gtcaccgcag ggcagctgga atggcagcat ggtagcacct cctaacagat 900

 taaatagatc acatttgctt ctaaaatt 928

<210> 5556
<211> 167
<212> PRT
<213> Homo sapien

<400> 5556
 Met Leu Pro Glu Lys Ala Leu His Gly His Pro Gln Leu Pro Arg
   1               5                  10                  15

 Thr Val Pro Thr Arg Ala Ala Met Arg Ala Ala Gly Thr Leu Leu
                  20                  25                  30

 Ala Phe Cys Cys Leu Val Leu Ser Thr Thr Gly Gly Pro Ser Pro
                  35                  40                  45

 Asp Thr Cys Ser Gln Asp Leu Asn Ser Arg Val Lys Pro Gly Phe
                  50                  55                  60

 Pro Lys Thr Ile Lys Thr Asn Asp Pro Gly Val Leu Gln Ala Ala
                  65                  70                  75

 Arg Tyr Ser Val Glu Lys Phe Asn Asn Cys Thr Asn Asp Met Phe
                  80                  85                  90

 Leu Phe Lys Glu Ser Arg Ile Thr Arg Ala Leu Val Gln Ile Val
                  95                 100                 105

 Lys Gly Leu Lys Tyr Met Leu Glu Val Glu Ile Gly Arg Thr Thr
                 110                 115                 120

 Cys Lys Lys Asn Gln His Leu Arg Leu Asp Asp Cys Asp Phe Gln
                 125                 130                 135

 Thr Asn His Thr Leu Lys Gln Thr Leu Ser Cys Tyr Ser Glu Val
                 140                 145                 150

 Trp Val Val Pro Trp Leu Gln His Phe Glu Val Pro Val Leu Arg
                 155                 160                 165

 Cys His


<210> 5557
<211> 2922
<212> DNA
<213> Homo sapien

<400> 5557
 ggacaccggg ccatgcacgc ccccaactga agctgcatct caaagccgaa 50

 gattccagca gcccagggga tttcaaagag ctcagactca gaggaacatc 100

 tgcggagaga cccccgaagc cctctccagg gcagtcctca tccagacgct 150

 ccgctagtgc agacaggagc gcgcagtggc cccggctcgc cgcgccatgg 200

 agcggatccc cagcgcgcaa ccaccccccg cctgcctgcc caaagcaccg 250

 ggactggagc acggagacct accagggatg taccctgccc acatgtacca 300

 agtgtacaag tcaagacggg gaataaagcg gagcgaggac agcaaggaga 350

 cctacaaatt gccgcaccgg ctcatcgaga aaaagagacg tgaccggatt 400

 aacgagtgca tcgcccagct gaaggatctc ctacccgaac atctcaaact 450

 tacaactttg ggtcacttgg aaaaagcagt ggttcttgaa cttaccttga 500

 agcatgtgaa agcactaaca aacctaattg atcagcagca gcagaaaatc 550

 attgccctgc agagtggttt acaagctggt gagctgtcag ggagaaatgt 600

 cgaaacaggt caagagatgt tctgctcagg tttccagaca tgtgcccggg 650

 aggtgcttca gtatctggcc aagcacgaga acactcggga cctgaagtct 700

 tcgcagcttg tcacccacct ccaccgggtg gtctcggagc tgctgcaggg 750

 tggtacctcc aggaagccat cagacccagc tcccaaagtg atggacttca 800

 aggaaaaacc cagctctccg gccaaaggtt cggaaggtcc tgggaaaaac 850

 tgcgtgccag tcatccagcg gactttcgct cactcgagtg gggagcagag 900

 cggcagcgac acggacacag acagtggcta tggaggagaa tcggagaagg 950

 gcgacttgcg cagtgagcag ccgtgcttca aaagtgacca cggacgcagg 1000

 ttcacgatgg gagaaaggat cggcgcaatt aagcaagagt ccgaagaacc 1050

 ccccacaaaa aagaaccgga tgcagctttc ggatgatgaa ggccatttca 1100

 ctagcagtga cctgatcagc tccccgttcc tgggcccaca cccacaccag 1150

 cctcctttct gcctgccctt ctacctgatc ccaccttcag cgactgccta 1200

 cctgcccatg ctggagaagt gctggtatcc cacctcagtg ccagtgctat 1250

 acccaggcct caacgcctct gccgcagccc tctctagctt catgaaccca 1300

 gacaagatct cggctccctt gctcatgccc cagagactcc cttctccctt 1350

 gccagctcat ccgtccgtcg actcttctgt cttgctccaa gctctgaagc 1400

 caatcccccc tttaaactta gaaaccaaag actaaactct ctaggggatc 1450

 ctgctgcttt gctttccttc ctcgctactt cctaaaaagc aacaaaaaag 1500

 tttttgtgaa tgctgcaaga ttgttgcatt gtgtatactg agataatctg 1550

 aggcatggag agcagattca gggtgtgtgt gtgtgtgtgt gtgtgtgtgt 1600

 gtatgtgcgt gtgcgtgcac atgtgtgcct gcgtgttggt ataggacttt 1650

 aaagctcctt ttggcatagg gaagtcacga aggattgctt gacatcagga 1700

 gacttggggg ggattgtagc agacgtctgg gcttttcccc acccagagaa 1750

 tagccccctt cgatacacat cagctggatt ttcaaaagct tcaaagtctt 1800

 ggtctgtgag tcactcttca gtttgggagc tgggtctgtg gctttgatca 1850

 gaaggtactt tcaaaagagg gctttccagg gctcagctcc caaccagctg 1900

 ttaggacccc acccttttgc ctttattgtc gacgtgactc accagacgtc 1950

 ggggagagag agcagtcaga ccgagctttc tgctaacatg gggaggtagc 2000

 aggcactggc atagcacggt agtggtttgg ggaggtttcc gcaggtctgc 2050

 tccccacccc tgcctcggaa gaataaagag aatgtagttc cctactcagg 2100

 ctttcgtagt gattagctta ctaaggaact gaaaatgggc cccttgtaca 2150

 agctgagctg ccccggaggg agggaggagt tccctgggct tctggcacct 2200

 gtttctaggc ctaaccatta gtacttactg tgcagggaac caaaccaagg 2250

 tctgagaaat gcggacaccc cgagcgagca ccccaaagtg cacaaagctg 2300

 agtaaaaagc tgcccccttc aaacagaact agactcagtt ttcaattcca 2350

 tcctaaaact ccttttaacc aagcttagct tctcaaaggc ctaaccaagc 2400

 cttggcaccg ccagatcctt tctgtaggct aattcctctt gcccaacggc 2450

 atatggagtg tccttattgc taaaaaggat tccgtctcct tcaaagaagt 2500

 tttatttttg gtccagagta cttgttttcc cgatgtgtcc agccagctcc 2550

 gcagcagctt ttcaagatgc actatgcctg attgctgatc gtgttttaac 2600

 tttttctttt cctgttttta ttttggtatt aagtcgttgc ctttatttgt 2650

 aaagctgtta taaatatata ttatataaat atattaaaaa ggaaaatgtt 2700

 tcagatgttt atttgtataa ttacttgatt cacacagtga gaaaaaatga 2750

 atgtattcct gtttttgaag agaagaataa tttttttttc tctagggaga 2800

 ggtacagtgt ttatattttg gagccttcct gaaggtgtaa aattgtaaat 2850

 atttttatct atgagtaaat gttaagtagt tgttttaaaa tacttaataa 2900

 aataattctt ttcctgtgga ag 2922

<210> 5558
<211> 412
<212> PRT
<213> Homo sapien

<400> 5558
 Met Glu Arg Ile Pro Ser Ala Gln Pro Pro Pro Ala Cys Leu Pro
   1               5                  10                  15

 Lys Ala Pro Gly Leu Glu His Gly Asp Leu Pro Gly Met Tyr Pro
                  20                  25                  30

 Ala His Met Tyr Gln Val Tyr Lys Ser Arg Arg Gly Ile Lys Arg
                  35                  40                  45

 Ser Glu Asp Ser Lys Glu Thr Tyr Lys Leu Pro His Arg Leu Ile
                  50                  55                  60

 Glu Lys Lys Arg Arg Asp Arg Ile Asn Glu Cys Ile Ala Gln Leu
                  65                  70                  75

 Lys Asp Leu Leu Pro Glu His Leu Lys Leu Thr Thr Leu Gly His
                  80                  85                  90

 Leu Glu Lys Ala Val Val Leu Glu Leu Thr Leu Lys His Val Lys
                  95                 100                 105

 Ala Leu Thr Asn Leu Ile Asp Gln Gln Gln Gln Lys Ile Ile Ala
                 110                 115                 120

 Leu Gln Ser Gly Leu Gln Ala Gly Glu Leu Ser Gly Arg Asn Val
                 125                 130                 135

 Glu Thr Gly Gln Glu Met Phe Cys Ser Gly Phe Gln Thr Cys Ala
                 140                 145                 150

 Arg Glu Val Leu Gln Tyr Leu Ala Lys His Glu Asn Thr Arg Asp
                 155                 160                 165

 Leu Lys Ser Ser Gln Leu Val Thr His Leu His Arg Val Val Ser
                 170                 175                 180

 Glu Leu Leu Gln Gly Gly Thr Ser Arg Lys Pro Ser Asp Pro Ala
                 185                 190                 195

 Pro Lys Val Met Asp Phe Lys Glu Lys Pro Ser Ser Pro Ala Lys
                 200                 205                 210

 Gly Ser Glu Gly Pro Gly Lys Asn Cys Val Pro Val Ile Gln Arg
                 215                 220                 225

 Thr Phe Ala His Ser Ser Gly Glu Gln Ser Gly Ser Asp Thr Asp
                 230                 235                 240

 Thr Asp Ser Gly Tyr Gly Gly Glu Ser Glu Lys Gly Asp Leu Arg
                 245                 250                 255

 Ser Glu Gln Pro Cys Phe Lys Ser Asp His Gly Arg Arg Phe Thr
                 260                 265                 270

 Met Gly Glu Arg Ile Gly Ala Ile Lys Gln Glu Ser Glu Glu Pro
                 275                 280                 285

 Pro Thr Lys Lys Asn Arg Met Gln Leu Ser Asp Asp Glu Gly His
                 290                 295                 300

 Phe Thr Ser Ser Asp Leu Ile Ser Ser Pro Phe Leu Gly Pro His
                 305                 310                 315

 Pro His Gln Pro Pro Phe Cys Leu Pro Phe Tyr Leu Ile Pro Pro
                 320                 325                 330

 Ser Ala Thr Ala Tyr Leu Pro Met Leu Glu Lys Cys Trp Tyr Pro
                 335                 340                 345

 Thr Ser Val Pro Val Leu Tyr Pro Gly Leu Asn Ala Ser Ala Ala
                 350                 355                 360

 Ala Leu Ser Ser Phe Met Asn Pro Asp Lys Ile Ser Ala Pro Leu
                 365                 370                 375

 Leu Met Pro Gln Arg Leu Pro Ser Pro Leu Pro Ala His Pro Ser
                 380                 385                 390

 Val Asp Ser Ser Val Leu Leu Gln Ala Leu Lys Pro Ile Pro Pro
                 395                 400                 405

 Leu Asn Leu Glu Thr Lys Asp
                 410

<210> 5559
<211> 1683
<212> DNA
<213> Homo sapien

<400> 5559
 atgggggacg ctcccagccc tgaagagaaa ctgcacctta tcacccggaa 50

 cctgcaggag gttctggggg aagagaagct gaaggagata ctgaaggagc 100

 gggaacttaa aatttactgg ggaacggcaa ccacgggcaa accacatgtg 150

 gcttactttg tgcccatgtc aaagattgca gacttcttaa aggcagggtg 200

 tgaggtaaca attctgtttg cggacctcca cgcatacctg gataacatga 250

 aagccccatg ggaacttcta gaactccgag tcagttacta tgagaatgtg 300

 atcaaagcaa tgctggagag cattggtgtg cccttggaga agctcaagtt 350

 catcaaaggc actgattacc agctcagcaa agagtacaca ctagatgtgt 400

 acagactctc ctccgtggtc acacagcacg attccaagaa ggctggagct 450

 gaggtggtaa agcaggtgga gcaccctttg ctgagtggcc tcttataccc 500

 cggactgcag gctttggatg aagagtattt aaaagtagat gcccaatttg 550

 gaggcattga tcagagaaag attttcacct ttgcagagaa gtacctccct 600

 gcacttggct attcaaaacg ggtccatctg atgaatccta tggttccagg 650

 attaacaggc agcaaaatga gctcttcaga agaggagtcc aagattgatc 700

 tccttgatcg gaaggaggat gtgaagaaaa aactgaagaa ggccttctgt 750

 gagccaggaa atgtggagaa caatggggtt ctgtccttca tcaagcatgt 800

 cctttttccc cttaagtccg agtttgtgat cctacgagat gagaaatggg 850

 gtggaaacaa aacctacaca gcttacgtgg acctggaaaa ggactttgct 900

 gctgaggttg tacatcctgg agacctgaag aattctgttg aagtcgcact 950

 gaacaagttg ctggatccaa tccgggaaaa gtttaatacc cctgccctga 1000

 aaaaactggc cagcgctgcc tacccagatc cctcaaagca gaagccaatg 1050

 gccaaaggcc ctgccaagaa ttcagaacca gaggaggtca tcccatcccg 1100

 gctggatatc cgtgtgggga aaatcatcac tgtggagaag cacccagatg 1150

 cagacagcct gtatgtagag aagattgacg tgggggaagc tgaaccacgg 1200

 actgtggtga gcggcctggt acagttcgtg cccaaggagg aactgcagga 1250

 caggctggta gtggtgctgt gcaacctgaa accccagaag atgagaggag 1300

 tcgagtccca aggcatgctt ctgtgtgctt ctatagaagg gataaaccgc 1350

 caggttgaac ctctggaccc tccggcaggc tctgctcctg gtgagcacgt 1400

 gtttgtgaag ggctatgaaa agggccaacc agatgaggag ctcaagccca 1450

 agaagaaagt cttcgagaag ttgcaggctg acttcaaaat ttctgaggag 1500

 tgcatcgcac agtggaagca aaccaacttc atgaccaagc tgggctccat 1550

 ttcctgtaaa tcgctgaaag gggggaacat tagctagcca gcccagcatc 1600

 ttcccccctt cttccaccac tgagtcatct gctgtctctt cagtctgctc 1650

 catccatcac ccatttaccc atctctcagg aca 1683

<210> 5560
<211> 528
<212> PRT
<213> Homo sapien

<400> 5560
 Met Gly Asp Ala Pro Ser Pro Glu Glu Lys Leu His Leu Ile Thr
   1               5                  10                  15

 Arg Asn Leu Gln Glu Val Leu Gly Glu Glu Lys Leu Lys Glu Ile
                  20                  25                  30

 Leu Lys Glu Arg Glu Leu Lys Ile Tyr Trp Gly Thr Ala Thr Thr
                  35                  40                  45

 Gly Lys Pro His Val Ala Tyr Phe Val Pro Met Ser Lys Ile Ala
                  50                  55                  60

 Asp Phe Leu Lys Ala Gly Cys Glu Val Thr Ile Leu Phe Ala Asp
                  65                  70                  75

 Leu His Ala Tyr Leu Asp Asn Met Lys Ala Pro Trp Glu Leu Leu
                  80                  85                  90

 Glu Leu Arg Val Ser Tyr Tyr Glu Asn Val Ile Lys Ala Met Leu
                  95                 100                 105

 Glu Ser Ile Gly Val Pro Leu Glu Lys Leu Lys Phe Ile Lys Gly
                 110                 115                 120

 Thr Asp Tyr Gln Leu Ser Lys Glu Tyr Thr Leu Asp Val Tyr Arg
                 125                 130                 135

 Leu Ser Ser Val Val Thr Gln His Asp Ser Lys Lys Ala Gly Ala
                 140                 145                 150

 Glu Val Val Lys Gln Val Glu His Pro Leu Leu Ser Gly Leu Leu
                 155                 160                 165

 Tyr Pro Gly Leu Gln Ala Leu Asp Glu Glu Tyr Leu Lys Val Asp
                 170                 175                 180

 Ala Gln Phe Gly Gly Ile Asp Gln Arg Lys Ile Phe Thr Phe Ala
                 185                 190                 195

 Glu Lys Tyr Leu Pro Ala Leu Gly Tyr Ser Lys Arg Val His Leu
                 200                 205                 210

 Met Asn Pro Met Val Pro Gly Leu Thr Gly Ser Lys Met Ser Ser
                 215                 220                 225

 Ser Glu Glu Glu Ser Lys Ile Asp Leu Leu Asp Arg Lys Glu Asp
                 230                 235                 240

 Val Lys Lys Lys Leu Lys Lys Ala Phe Cys Glu Pro Gly Asn Val
                 245                 250                 255

 Glu Asn Asn Gly Val Leu Ser Phe Ile Lys His Val Leu Phe Pro
                 260                 265                 270

 Leu Lys Ser Glu Phe Val Ile Leu Arg Asp Glu Lys Trp Gly Gly
                 275                 280                 285

 Asn Lys Thr Tyr Thr Ala Tyr Val Asp Leu Glu Lys Asp Phe Ala
                 290                 295                 300

 Ala Glu Val Val His Pro Gly Asp Leu Lys Asn Ser Val Glu Val
                 305                 310                 315

 Ala Leu Asn Lys Leu Leu Asp Pro Ile Arg Glu Lys Phe Asn Thr
                 320                 325                 330

 Pro Ala Leu Lys Lys Leu Ala Ser Ala Ala Tyr Pro Asp Pro Ser
                 335                 340                 345

 Lys Gln Lys Pro Met Ala Lys Gly Pro Ala Lys Asn Ser Glu Pro
                 350                 355                 360

 Glu Glu Val Ile Pro Ser Arg Leu Asp Ile Arg Val Gly Lys Ile
                 365                 370                 375

 Ile Thr Val Glu Lys His Pro Asp Ala Asp Ser Leu Tyr Val Glu
                 380                 385                 390

 Lys Ile Asp Val Gly Glu Ala Glu Pro Arg Thr Val Val Ser Gly
                 395                 400                 405

 Leu Val Gln Phe Val Pro Lys Glu Glu Leu Gln Asp Arg Leu Val
                 410                 415                 420

 Val Val Leu Cys Asn Leu Lys Pro Gln Lys Met Arg Gly Val Glu
                 425                 430                 435

 Ser Gln Gly Met Leu Leu Cys Ala Ser Ile Glu Gly Ile Asn Arg
                 440                 445                 450

 Gln Val Glu Pro Leu Asp Pro Pro Ala Gly Ser Ala Pro Gly Glu
                 455                 460                 465

 His Val Phe Val Lys Gly Tyr Glu Lys Gly Gln Pro Asp Glu Glu
                 470                 475                 480

 Leu Lys Pro Lys Lys Lys Val Phe Glu Lys Leu Gln Ala Asp Phe
                 485                 490                 495

 Lys Ile Ser Glu Glu Cys Ile Ala Gln Trp Lys Gln Thr Asn Phe
                 500                 505                 510

 Met Thr Lys Leu Gly Ser Ile Ser Cys Lys Ser Leu Lys Gly Gly
                 515                 520                 525

 Asn Ile Ser


<210> 5561
<211> 3122
<212> DNA
<213> Homo sapien

<400> 5561
 cgctgcggcc gctatcccct ccggaccatg gccgacgacg acgtgctgtt 50

 cgaggatgtg tacgagctgt gcgaggtgat cggaaagggt cccttcagtg 100

 ttgtacgacg atgtatcaac agagaaactg ggcaacaatt tgctgtaaaa 150

 attgttgatg tagccaagtt cacatcaagt ccagggttaa gtacagaaga 200

 tctaaagcgg gaagccagta tctgtcatat gctgaaacat ccacacattg 250

 tagagttatt ggagacatat agctcagatg gaatgcttta catggttttc 300

 gaatttatgg atggagcaga tctgtgtttt gaaatcgtaa agcgagctga 350

 cgctggtttt gtgtacagtg aagctgtagc cagccattat atgagacaga 400

 tactggaagc tctacgctac tgccatgata ataacataat tcacagggat 450

 gtgaagcccc actgtgttct ccttgcctca aaagaaaact cggcacctgt 500

 taaacttgga ggctttgggg tagctattca attaggggag tctggacttg 550

 tagctggagg acgtgttgga acacctcatt ttatggcacc agaagtggtc 600

 aaaagagagc cttacggaaa gcctgtagac gtctgggggt gcggtgtgat 650

 cctttttatc ctgctcagtg gttgtttgcc tttttacgga accaaggaaa 700

 gattgtttga aggcattatt aaaggaaaat ataagatgaa tccaaggcag 750

 tggagccata tctctgaaag tgccaaagac ctagtacgtc gcatgctgat 800

 gctggatcca gctgaaagga tcactgttta tgaagcactg aatcacccat 850

 ggcttaagga gcgggatcgt tacgcctaca agattcatct tccagaaaca 900

 gtagagcagc tgaggaaatt caatgcaagg aggaaactaa agggtgcagt 950

 actagccgct gtgtcaagtc acaaattcaa ctcattctat ggggatcccc 1000

 ctgaagagtt accagatttc tccgaagacc ctacctcctc agggcttcta 1050

 gcagcagaaa gagcagtctc acaggtgctg gacagcctgg aagagattca 1100

 tgcgcttaca gactgcagtg aaaaggacct agattttcta cacagtgttt 1150

 tccaggatca gcatcttcac acactactag atctgtatga caaaattaac 1200

 acaaagtctt caccacaaat caggaatcct ccaagcgatg cagtacagag 1250

 agccaaagag gtattggaag aaatttcatg ttaccctgag aataacgacg 1300

 caaaggaact aaagcgtatt ttaacacaac ctcatttcat ggccttactt 1350

 cagactcacg acgtagtggc acatgaagtt tacagtgatg aagcattgag 1400

 ggtcacacct cctcccacct ctccctattt aaacggcgat tctccagaaa 1450

 gtgctaacgg aggcatggat atggagaatg tgaccagagt tcggctggta 1500

 cagtttcaaa agaacacaga tgaaccaatg ggaatcactt taaaaatgaa 1550

 tgaactaaat cattgtattg ttgcaagaat tatgcatggg ggcatgattc 1600

 acaggcaagg tacacttcat gttggtgatg aaattcgaga aatcaatggc 1650

 atcagtgtgg ctaaccaaac agtggaacaa ctgcaaaaaa tgcttaggga 1700

 aatgcggggg agtattacct tcaagattgt gccaagttac cgcactcagt 1750

 cttcgtcctg tgagagagat tccccttcca cttccagaca gtccccagct 1800

 aatggtcata gcagcactaa caattctgtt tcggacttgc catcaactac 1850

 ccaaccaaaa ggacgacaga tctatgtaag agcacaattt gaatatgatc 1900

 cagccaagga tgacctcatc ccctgtaaag aagctggcat tcgattcaga 1950

 gttggtgaca tcatccagat tattagtaag gatgatcata attggtggca 2000

 gggtaaactg gaaaactcca aaaatggaac tgcaggtctc attccttctt 2050

 ctgaacttca ggaatggcga gtagcttgca ttgccatgga gaagaccaaa 2100

 caggagcagc aggccagctg tacttggttt ggcaagaaaa agaagcagta 2150

 caaagataaa tatttggcaa agcacaatgc agatcttgtc acatatgaag 2200

 aagtagtaaa actgccagca ttcaagagga aaacactagt cttattaggc 2250

 gcacatggtg ttgggagaag acacataaaa aacactctca tcacaaagca 2300

 cccagaccgg tttgcgtacc ctattccaca tacaaccaga cctccaaaga 2350

 gagacgaaga aaatggaaag aattattact ttgtatctca tgaccaaatg 2400

 atgcaagaca tctctaataa cgagtacttg gagtacggca gccacgagga 2450

 tgcgatgtat gggacaaaac tggagaccat ccggaagatc cacgagcagg 2500

 ggctgattgc aatactggac gtggagcctc aggcactgaa ggtcctgaga 2550

 actgcagagt ttgctccttt tgttgttttc attgctgcac caactattac 2600

 tccaggttta aatgaggatg aatctcttca gcgtctgcag aaggagtctg 2650

 acatcttaca gagaacatat gcacactact tcgatctcac aattatcaac 2700

 aatgaaattg atgagacaat cagacatctg gaggaagctg ttgagctcgt 2750

 gtgcacagcc ccacagtggg tccctgtctc ctgggtctat taggcctctc 2800

 cccagatatc tgagcataac tgggagcacc tcatttgtgg aaaagcctct 2850

 ttgttatcgg ccttgtgtca gcaggtcatg gtccctagag actacctagt 2900

 tgtagtgtga cctacattta taattattgt catgtccgaa tagataggag 2950

 gagaaaaaca attacacact aatttaaaga gacagtatct tttttaatca 3000

 gttctcctaa actttaataa aatgtatctt taaatgtatg tattattcaa 3050

 tcctttggaa tgttatattt ttggaaatca tagcttttta tttccaaggc 3100

 ccctaaaact gcacaaaata ga 3122

<210> 5562
<211> 921
<212> PRT
<213> Homo sapien

<400> 5562
 Met Ala Asp Asp Asp Val Leu Phe Glu Asp Val Tyr Glu Leu Cys
   1               5                  10                  15

 Glu Val Ile Gly Lys Gly Pro Phe Ser Val Val Arg Arg Cys Ile
                  20                  25                  30

 Asn Arg Glu Thr Gly Gln Gln Phe Ala Val Lys Ile Val Asp Val
                  35                  40                  45

 Ala Lys Phe Thr Ser Ser Pro Gly Leu Ser Thr Glu Asp Leu Lys
                  50                  55                  60

 Arg Glu Ala Ser Ile Cys His Met Leu Lys His Pro His Ile Val
                  65                  70                  75

 Glu Leu Leu Glu Thr Tyr Ser Ser Asp Gly Met Leu Tyr Met Val
                  80                  85                  90

 Phe Glu Phe Met Asp Gly Ala Asp Leu Cys Phe Glu Ile Val Lys
                  95                 100                 105

 Arg Ala Asp Ala Gly Phe Val Tyr Ser Glu Ala Val Ala Ser His
                 110                 115                 120

 Tyr Met Arg Gln Ile Leu Glu Ala Leu Arg Tyr Cys His Asp Asn
                 125                 130                 135

 Asn Ile Ile His Arg Asp Val Lys Pro His Cys Val Leu Leu Ala
                 140                 145                 150

 Ser Lys Glu Asn Ser Ala Pro Val Lys Leu Gly Gly Phe Gly Val
                 155                 160                 165

 Ala Ile Gln Leu Gly Glu Ser Gly Leu Val Ala Gly Gly Arg Val
                 170                 175                 180

 Gly Thr Pro His Phe Met Ala Pro Glu Val Val Lys Arg Glu Pro
                 185                 190                 195

 Tyr Gly Lys Pro Val Asp Val Trp Gly Cys Gly Val Ile Leu Phe
                 200                 205                 210

 Ile Leu Leu Ser Gly Cys Leu Pro Phe Tyr Gly Thr Lys Glu Arg
                 215                 220                 225

 Leu Phe Glu Gly Ile Ile Lys Gly Lys Tyr Lys Met Asn Pro Arg
                 230                 235                 240

 Gln Trp Ser His Ile Ser Glu Ser Ala Lys Asp Leu Val Arg Arg
                 245                 250                 255

 Met Leu Met Leu Asp Pro Ala Glu Arg Ile Thr Val Tyr Glu Ala
                 260                 265                 270

 Leu Asn His Pro Trp Leu Lys Glu Arg Asp Arg Tyr Ala Tyr Lys
                 275                 280                 285

 Ile His Leu Pro Glu Thr Val Glu Gln Leu Arg Lys Phe Asn Ala
                 290                 295                 300

 Arg Arg Lys Leu Lys Gly Ala Val Leu Ala Ala Val Ser Ser His
                 305                 310                 315

 Lys Phe Asn Ser Phe Tyr Gly Asp Pro Pro Glu Glu Leu Pro Asp
                 320                 325                 330

 Phe Ser Glu Asp Pro Thr Ser Ser Gly Leu Leu Ala Ala Glu Arg
                 335                 340                 345

 Ala Val Ser Gln Val Leu Asp Ser Leu Glu Glu Ile His Ala Leu
                 350                 355                 360

 Thr Asp Cys Ser Glu Lys Asp Leu Asp Phe Leu His Ser Val Phe
                 365                 370                 375

 Gln Asp Gln His Leu His Thr Leu Leu Asp Leu Tyr Asp Lys Ile
                 380                 385                 390

 Asn Thr Lys Ser Ser Pro Gln Ile Arg Asn Pro Pro Ser Asp Ala
                 395                 400                 405

 Val Gln Arg Ala Lys Glu Val Leu Glu Glu Ile Ser Cys Tyr Pro
                 410                 415                 420

 Glu Asn Asn Asp Ala Lys Glu Leu Lys Arg Ile Leu Thr Gln Pro
                 425                 430                 435

 His Phe Met Ala Leu Leu Gln Thr His Asp Val Val Ala His Glu
                 440                 445                 450

 Val Tyr Ser Asp Glu Ala Leu Arg Val Thr Pro Pro Pro Thr Ser
                 455                 460                 465

 Pro Tyr Leu Asn Gly Asp Ser Pro Glu Ser Ala Asn Gly Gly Met
                 470                 475                 480

 Asp Met Glu Asn Val Thr Arg Val Arg Leu Val Gln Phe Gln Lys
                 485                 490                 495

 Asn Thr Asp Glu Pro Met Gly Ile Thr Leu Lys Met Asn Glu Leu
                 500                 505                 510

 Asn His Cys Ile Val Ala Arg Ile Met His Gly Gly Met Ile His
                 515                 520                 525

 Arg Gln Gly Thr Leu His Val Gly Asp Glu Ile Arg Glu Ile Asn
                 530                 535                 540

 Gly Ile Ser Val Ala Asn Gln Thr Val Glu Gln Leu Gln Lys Met
                 545                 550                 555

 Leu Arg Glu Met Arg Gly Ser Ile Thr Phe Lys Ile Val Pro Ser
                 560                 565                 570

 Tyr Arg Thr Gln Ser Ser Ser Cys Glu Arg Asp Ser Pro Ser Thr
                 575                 580                 585

 Ser Arg Gln Ser Pro Ala Asn Gly His Ser Ser Thr Asn Asn Ser
                 590                 595                 600

 Val Ser Asp Leu Pro Ser Thr Thr Gln Pro Lys Gly Arg Gln Ile
                 605                 610                 615

 Tyr Val Arg Ala Gln Phe Glu Tyr Asp Pro Ala Lys Asp Asp Leu
                 620                 625                 630

 Ile Pro Cys Lys Glu Ala Gly Ile Arg Phe Arg Val Gly Asp Ile
                 635                 640                 645

 Ile Gln Ile Ile Ser Lys Asp Asp His Asn Trp Trp Gln Gly Lys
                 650                 655                 660

 Leu Glu Asn Ser Lys Asn Gly Thr Ala Gly Leu Ile Pro Ser Ser
                 665                 670                 675

 Glu Leu Gln Glu Trp Arg Val Ala Cys Ile Ala Met Glu Lys Thr
                 680                 685                 690

 Lys Gln Glu Gln Gln Ala Ser Cys Thr Trp Phe Gly Lys Lys Lys
                 695                 700                 705

 Lys Gln Tyr Lys Asp Lys Tyr Leu Ala Lys His Asn Ala Asp Leu
                 710                 715                 720

 Val Thr Tyr Glu Glu Val Val Lys Leu Pro Ala Phe Lys Arg Lys
                 725                 730                 735

 Thr Leu Val Leu Leu Gly Ala His Gly Val Gly Arg Arg His Ile
                 740                 745                 750

 Lys Asn Thr Leu Ile Thr Lys His Pro Asp Arg Phe Ala Tyr Pro
                 755                 760                 765

 Ile Pro His Thr Thr Arg Pro Pro Lys Arg Asp Glu Glu Asn Gly
                 770                 775                 780

 Lys Asn Tyr Tyr Phe Val Ser His Asp Gln Met Met Gln Asp Ile
                 785                 790                 795

 Ser Asn Asn Glu Tyr Leu Glu Tyr Gly Ser His Glu Asp Ala Met
                 800                 805                 810

 Tyr Gly Thr Lys Leu Glu Thr Ile Arg Lys Ile His Glu Gln Gly
                 815                 820                 825

 Leu Ile Ala Ile Leu Asp Val Glu Pro Gln Ala Leu Lys Val Leu
                 830                 835                 840

 Arg Thr Ala Glu Phe Ala Pro Phe Val Val Phe Ile Ala Ala Pro
                 845                 850                 855

 Thr Ile Thr Pro Gly Leu Asn Glu Asp Glu Ser Leu Gln Arg Leu
                 860                 865                 870

 Gln Lys Glu Ser Asp Ile Leu Gln Arg Thr Tyr Ala His Tyr Phe
                 875                 880                 885

 Asp Leu Thr Ile Ile Asn Asn Glu Ile Asp Glu Thr Ile Arg His
                 890                 895                 900

 Leu Glu Glu Ala Val Glu Leu Val Cys Thr Ala Pro Gln Trp Val
                 905                 910                 915

 Pro Val Ser Trp Val Tyr
                 920

<210> 5563
<211> 1094
<212> DNA
<213> Homo sapien

<400> 5563
 ctccggctgg ccccttctgt aggatggtag cacacaacca ggtggcagcc 50

 gacaatgcag tctccacagc agcagagccc cgacggcggc cagaaccttc 100

 ctcctcttcc tcctcctcgc ccgcggcccc cgcgcgcccg cggccgtgcc 150

 ccgcggtccc ggccccggcc cccggcgaca cgcacttccg cacattccgt 200

 tcgcacgccg attaccggcg catcacgcgc gccagcgcgc tcctggacgc 250

 ctgcggattc tactgggggc ccctgagcgt gcacggggcg cacgagcggc 300

 tgcgcgccga gcccgtgggc accttcctgg tgcgcgacag ccgccagcgg 350

 aactgctttt tcgcccttag cgtgaagatg gcctcgggac ccacgagcat 400

 ccgcgtgcac tttcaggccg gccgctttca cctggatggc agccgcgaga 450

 gcttcgactg cctcttcgag ctgctggagc actacgtggc ggcgccgcgc 500

 cgcatgctgg gggccccgct gcgccagcgc cgcgtgcggc cgctgcagga 550

 gctgtgccgc cagcgcatcg tggccaccgt gggccgcgag aacctggctc 600

 gcatccccct caaccccgtc ctccgcgact acctgagctc cttccccttc 650

 cagatttgac cggcagcgcc cgccgtgcac gcagcattaa ctgggatgcc 700

 gtgttatttt gttattactt gcctggaacc atgtgggtac cctccccggc 750

 ctgggttgga gggagcggat gggtgtaggg gcgaggcgcc tcccgccctc 800

 ggctggagac gaggccgcag accccttctc acctcttgag ggggtcctcc 850

 ccctcctggt gctccctctg ggtccccctg gttgttgtag cagcttaact 900

 gtatctggag ccaggacctg aactcgcacc tcctacctct tcatgtttac 950

 atatacccag tatctttgca caaaccaggg gttgggggag ggtctctggc 1000

 tttatttttc tgctgtgcag aatcctattt tatatttttt aaagtcagtt 1050

 taggtaataa actttattat gaaagttttt ttttttaaaa aaaa 1094

<210> 5564
<211> 211
<212> PRT
<213> Homo sapien

<400> 5564
 Met Val Ala His Asn Gln Val Ala Ala Asp Asn Ala Val Ser Thr
   1               5                  10                  15

 Ala Ala Glu Pro Arg Arg Arg Pro Glu Pro Ser Ser Ser Ser Ser
                  20                  25                  30

 Ser Ser Pro Ala Ala Pro Ala Arg Pro Arg Pro Cys Pro Ala Val
                  35                  40                  45

 Pro Ala Pro Ala Pro Gly Asp Thr His Phe Arg Thr Phe Arg Ser
                  50                  55                  60

 His Ala Asp Tyr Arg Arg Ile Thr Arg Ala Ser Ala Leu Leu Asp
                  65                  70                  75

 Ala Cys Gly Phe Tyr Trp Gly Pro Leu Ser Val His Gly Ala His
                  80                  85                  90

 Glu Arg Leu Arg Ala Glu Pro Val Gly Thr Phe Leu Val Arg Asp
                  95                 100                 105

 Ser Arg Gln Arg Asn Cys Phe Phe Ala Leu Ser Val Lys Met Ala
                 110                 115                 120

 Ser Gly Pro Thr Ser Ile Arg Val His Phe Gln Ala Gly Arg Phe
                 125                 130                 135

 His Leu Asp Gly Ser Arg Glu Ser Phe Asp Cys Leu Phe Glu Leu
                 140                 145                 150

 Leu Glu His Tyr Val Ala Ala Pro Arg Arg Met Leu Gly Ala Pro
                 155                 160                 165

 Leu Arg Gln Arg Arg Val Arg Pro Leu Gln Glu Leu Cys Arg Gln
                 170                 175                 180

 Arg Ile Val Ala Thr Val Gly Arg Glu Asn Leu Ala Arg Ile Pro
                 185                 190                 195

 Leu Asn Pro Val Leu Arg Asp Tyr Leu Ser Ser Phe Pro Phe Gln
                 200                 205                 210

 Ile


<210> 5565
<211> 1222
<212> DNA
<213> Homo sapien

<400> 5565
 cgggccctgc gggcgcgggg ctgaaggcgg aaccacgacg ggcagagagc 50

 acggagccgg gaagcccctg ggcgcccgtc ggagggctat ggagcagcgg 100

 ccgcggggct gcgcggcggt ggcggcggcg ctcctcctgg tgctgctggg 150

 ggcccgggcc cagggcggca ctcgtagccc caggtgtgac tgtgccggtg 200

 acttccacaa gaagattggt ctgttttgtt gcagaggctg cccagcggcc 250

 tcccaggtgg cgctggagaa ctgttcagca gtggccgaca cccgctgtgg 300

 ctgtaagcca ggctggtttg tggagtgcca ggtcagccaa tgtgtcagca 350

 gttcaccctt ctactgccaa ccatgcctag actgcggggc cctgcaccgc 400

 cacacacggc tactctgcca cccatctgtc acccttggac agcgcccaca 450

 cccttctagc acctcctgac agcagtgaga agatctgcac cgtccagttg 500

 gtgggtaaca gctggacccc tggctacccc gagacccagg aggcgctctg 550

 cccgcaggtg acatggtcct gggaccagtt gcccagcaga gctcttggcc 600

 ccgctgctgc gcccacactc tcgccagagt ccccagccgg ctcgccagcc 650

 atgatgctgc agccgggccc gcagctctac gacgtgatgg acgcggtccc 700

 agcgcggcgc tggaaggagt tcgtgcgcac gctggggctg cgcgaggcag 750

 agatcgaagc cgtggaggtg gagatcggcc gcttccgaga ccagcagtac 800

 gagatgctca agcgctggcg ccagcagcag cccgcgggcc tcggagccgt 850

 ttacgcggcc ctggagcgca tggggctgga cggctgcgtg gaagacttgc 900

 gcagccgcct gcagcgcggc ccgtgacacg gcgcccactt gccacctagg 950

 cgctctggtg gcccttgcag aagccctaag tacggttact tatgcgtgta 1000

 gacattttat gtcacttatt aagccgctgg cacggccctg cgtagcagca 1050

 ccagccggcc ccacccctgc tcgcccctat cgctccagcc aaggcgaaga 1100

 agcacgaacg aatgtcgaga gggggtgaag acatttctca acttctcggc 1150

 cggagtttgg ctgagatcgc ggtattaaat ctgtgaaaga aaacaaaaca 1200

 aaacaaaaaa aaaaaaaaaa aa 1222

<210> 5566
<211> 126
<212> PRT
<213> Homo sapien

<400> 5566
 Met Glu Gln Arg Pro Arg Gly Cys Ala Ala Val Ala Ala Ala Leu
   1               5                  10                  15

 Leu Leu Val Leu Leu Gly Ala Arg Ala Gln Gly Gly Thr Arg Ser
                  20                  25                  30

 Pro Arg Cys Asp Cys Ala Gly Asp Phe His Lys Lys Ile Gly Leu
                  35                  40                  45

 Phe Cys Cys Arg Gly Cys Pro Ala Ala Ser Gln Val Ala Leu Glu
                  50                  55                  60

 Asn Cys Ser Ala Val Ala Asp Thr Arg Cys Gly Cys Lys Pro Gly
                  65                  70                  75

 Trp Phe Val Glu Cys Gln Val Ser Gln Cys Val Ser Ser Ser Pro
                  80                  85                  90

 Phe Tyr Cys Gln Pro Cys Leu Asp Cys Gly Ala Leu His Arg His
                  95                 100                 105

 Thr Arg Leu Leu Cys His Pro Ser Val Thr Leu Gly Gln Arg Pro
                 110                 115                 120

 His Pro Ser Ser Thr Ser
                 125

<210> 5567
<211> 2446
<212> DNA
<213> Homo sapien

<400> 5567
 gcgccgcggc gcggagtccc ggctgcggga tagaccgagg gccatggccg 50

 cctctcccgg acccgccggc gttggcggcg ccggagcagt ctacggctcc 100

 ggctcttcgg gcttcgccct cgactcggga ctggagatca aaactcgctc 150

 ggtggagcag acgctactcc cgctggtttc tcagatcacc acgcttatta 200

 atcataaaga taataccaaa aagtctgata aaactctgca agcaattcag 250

 cgtgtaggac aagctgtcaa cttggcagtt ggaagatttg ttaaagtagg 300

 agaagctata gccaatgaaa actgggattt gaaagaagaa ataaatattg 350

 cttgtattga agctaaacaa gcaggagaaa caattgcagc acttacagac 400

 ataaccaact tgaaccatct ggaatctgat gggcagatca caatttttac 450

 agacaaaaca ggagtgataa aggctgcaag attacttctt tcttcagtga 500

 caaaagtgtt gttgctggca gaccgagtag tcattaaaca gataataaca 550

 tcaagaaata aggttctcgc aactatggaa agactagaga aagtgaatag 600

 ctttcaagag tttgtccaaa tattcagtca atttggaaat gaaatggtgg 650

 agtttgcaca tctgagtgga gatagacaaa atgatttgaa agatgaaaag 700

 aaaaaggcaa aaatggcagc agctagggca gttcttgaaa agtgtacaat 750

 gatgcttctc acagcttcaa agacatgtct gaggcatcct aactgcgaat 800

 cagcccataa aaacaaagaa ggagtatttg accgtatgaa agtggcattg 850

 gataaggtca ttgaaattgt gactgactgt aaaccgaatg gagagactga 900

 catttcatct atcagtattt ttactggaat taaggaattc aagatgaata 950

 ttgaagctct tcgggagaat ctttattttc agtccaaaga gaacctttct 1000

 gtgacattgg aagtcatctt ggagcgtatg gaggacttta ctgattctgc 1050

 ctacaccagc catgagcaca gagaacgcat cttggaactg tcaactcagg 1100

 cgagaatgga actgcagcag ttaatttctg tgtggattca agctcaaagc 1150

 aagaaaacaa aaagcatcgc tgaagaactg gaactcagta ttttgaaaat 1200

 cagtcacagt cttaatgaac ttaagaaaga acttcatagt acagcgacac 1250

 agctggcagc agatctatta aaataccatg ctgatcatgt ggttctaaaa 1300

 gcattaaaac ttactggagt agaaggaaat ttagaagctt tggctgaata 1350

 tgcctgtaaa ctctctgaac agaaagagca gcttgttgag acctgtcgat 1400

 tgttacgaca catatctggg acagaacctc tggaaataac ctgtatacat 1450

 gcagaggaga catttcaggt gactggccaa cagataattt ctgctgctga 1500

 aacattgaca ttgcatccat ctagtaaaat tgctaaagaa aacctagatg 1550

 tattttgtga agcttgggaa tcccaaatta gtgacatgtc aacactgctg 1600

 agagaaatca atgacgtgtt tgaaggaaga cgaggagaga agtatggcta 1650

 cctttcactt ccaaagccaa tgaagaataa tgcaaacctg aaatcattaa 1700

 agccagacaa gcctgactct gaggagcaag ccaagatagc aaagcttgga 1750

 cttaagctgg gtttgctcac ctctgacgct gactgcgaaa ttgagaagtg 1800

 ggaagatcag gagaatgaga ttgttcaata tggacggaac atgtccagta 1850

 tggcctattc tctgtattta tttactagag gagaggggcc actgaaaact 1900

 tcccaggatt taattcatca actagaggtt tttgctgcag agggtttaaa 1950

 gcttacttcc agtgttcaag ctttttcaaa acagctgaaa gacgatgaca 2000

 agcttatgct tctcctggaa ataaacaagc taattcctct atgccaccag 2050

 ctccagacag taactaagac ttctttgcag aataaagtat ttctaaaggt 2100

 tgacaagtgt attacgaaga caagatccat gatggctctc ttagtccaac 2150

 ttctttcact ttgttataaa ctgctgaaga agcttcagat ggaaaataac 2200

 ggatgggtct cagttacaaa taaggacact atggatagta aaacttgaga 2250

 agcttttggg gtcagatctc tggaacatca tgtgatgaag ctgacatttt 2300

 taaaaatcaa atgatccttt atcttttcag aaattcatca attttataaa 2350

 gaaaacaata ttgaaatttt gctctatttt ctgatcatga aactgattgt 2400

 aaagcttttt gacaactaat aaatgtcttg gtaattgcta gattct 2446

<210> 5568
<211> 734
<212> PRT
<213> Homo sapien

<400> 5568
 Met Ala Ala Ser Pro Gly Pro Ala Gly Val Gly Gly Ala Gly Ala
   1               5                  10                  15

 Val Tyr Gly Ser Gly Ser Ser Gly Phe Ala Leu Asp Ser Gly Leu
                  20                  25                  30

 Glu Ile Lys Thr Arg Ser Val Glu Gln Thr Leu Leu Pro Leu Val
                  35                  40                  45

 Ser Gln Ile Thr Thr Leu Ile Asn His Lys Asp Asn Thr Lys Lys
                  50                  55                  60

 Ser Asp Lys Thr Leu Gln Ala Ile Gln Arg Val Gly Gln Ala Val
                  65                  70                  75

 Asn Leu Ala Val Gly Arg Phe Val Lys Val Gly Glu Ala Ile Ala
                  80                  85                  90

 Asn Glu Asn Trp Asp Leu Lys Glu Glu Ile Asn Ile Ala Cys Ile
                  95                 100                 105

 Glu Ala Lys Gln Ala Gly Glu Thr Ile Ala Ala Leu Thr Asp Ile
                 110                 115                 120

 Thr Asn Leu Asn His Leu Glu Ser Asp Gly Gln Ile Thr Ile Phe
                 125                 130                 135

 Thr Asp Lys Thr Gly Val Ile Lys Ala Ala Arg Leu Leu Leu Ser
                 140                 145                 150

 Ser Val Thr Lys Val Leu Leu Leu Ala Asp Arg Val Val Ile Lys
                 155                 160                 165

 Gln Ile Ile Thr Ser Arg Asn Lys Val Leu Ala Thr Met Glu Arg
                 170                 175                 180

 Leu Glu Lys Val Asn Ser Phe Gln Glu Phe Val Gln Ile Phe Ser
                 185                 190                 195

 Gln Phe Gly Asn Glu Met Val Glu Phe Ala His Leu Ser Gly Asp
                 200                 205                 210

 Arg Gln Asn Asp Leu Lys Asp Glu Lys Lys Lys Ala Lys Met Ala
                 215                 220                 225

 Ala Ala Arg Ala Val Leu Glu Lys Cys Thr Met Met Leu Leu Thr
                 230                 235                 240

 Ala Ser Lys Thr Cys Leu Arg His Pro Asn Cys Glu Ser Ala His
                 245                 250                 255

 Lys Asn Lys Glu Gly Val Phe Asp Arg Met Lys Val Ala Leu Asp
                 260                 265                 270

 Lys Val Ile Glu Ile Val Thr Asp Cys Lys Pro Asn Gly Glu Thr
                 275                 280                 285

 Asp Ile Ser Ser Ile Ser Ile Phe Thr Gly Ile Lys Glu Phe Lys
                 290                 295                 300

 Met Asn Ile Glu Ala Leu Arg Glu Asn Leu Tyr Phe Gln Ser Lys
                 305                 310                 315

 Glu Asn Leu Ser Val Thr Leu Glu Val Ile Leu Glu Arg Met Glu
                 320                 325                 330

 Asp Phe Thr Asp Ser Ala Tyr Thr Ser His Glu His Arg Glu Arg
                 335                 340                 345

 Ile Leu Glu Leu Ser Thr Gln Ala Arg Met Glu Leu Gln Gln Leu
                 350                 355                 360

 Ile Ser Val Trp Ile Gln Ala Gln Ser Lys Lys Thr Lys Ser Ile
                 365                 370                 375

 Ala Glu Glu Leu Glu Leu Ser Ile Leu Lys Ile Ser His Ser Leu
                 380                 385                 390

 Asn Glu Leu Lys Lys Glu Leu His Ser Thr Ala Thr Gln Leu Ala
                 395                 400                 405

 Ala Asp Leu Leu Lys Tyr His Ala Asp His Val Val Leu Lys Ala
                 410                 415                 420

 Leu Lys Leu Thr Gly Val Glu Gly Asn Leu Glu Ala Leu Ala Glu
                 425                 430                 435

 Tyr Ala Cys Lys Leu Ser Glu Gln Lys Glu Gln Leu Val Glu Thr
                 440                 445                 450

 Cys Arg Leu Leu Arg His Ile Ser Gly Thr Glu Pro Leu Glu Ile
                 455                 460                 465

 Thr Cys Ile His Ala Glu Glu Thr Phe Gln Val Thr Gly Gln Gln
                 470                 475                 480

 Ile Ile Ser Ala Ala Glu Thr Leu Thr Leu His Pro Ser Ser Lys
                 485                 490                 495

 Ile Ala Lys Glu Asn Leu Asp Val Phe Cys Glu Ala Trp Glu Ser
                 500                 505                 510

 Gln Ile Ser Asp Met Ser Thr Leu Leu Arg Glu Ile Asn Asp Val
                 515                 520                 525

 Phe Glu Gly Arg Arg Gly Glu Lys Tyr Gly Tyr Leu Ser Leu Pro
                 530                 535                 540

 Lys Pro Met Lys Asn Asn Ala Asn Leu Lys Ser Leu Lys Pro Asp
                 545                 550                 555

 Lys Pro Asp Ser Glu Glu Gln Ala Lys Ile Ala Lys Leu Gly Leu
                 560                 565                 570

 Lys Leu Gly Leu Leu Thr Ser Asp Ala Asp Cys Glu Ile Glu Lys
                 575                 580                 585

 Trp Glu Asp Gln Glu Asn Glu Ile Val Gln Tyr Gly Arg Asn Met
                 590                 595                 600

 Ser Ser Met Ala Tyr Ser Leu Tyr Leu Phe Thr Arg Gly Glu Gly
                 605                 610                 615

 Pro Leu Lys Thr Ser Gln Asp Leu Ile His Gln Leu Glu Val Phe
                 620                 625                 630

 Ala Ala Glu Gly Leu Lys Leu Thr Ser Ser Val Gln Ala Phe Ser
                 635                 640                 645

 Lys Gln Leu Lys Asp Asp Asp Lys Leu Met Leu Leu Leu Glu Ile
                 650                 655                 660

 Asn Lys Leu Ile Pro Leu Cys His Gln Leu Gln Thr Val Thr Lys
                 665                 670                 675

 Thr Ser Leu Gln Asn Lys Val Phe Leu Lys Val Asp Lys Cys Ile
                 680                 685                 690

 Thr Lys Thr Arg Ser Met Met Ala Leu Leu Val Gln Leu Leu Ser
                 695                 700                 705

 Leu Cys Tyr Lys Leu Leu Lys Lys Leu Gln Met Glu Asn Asn Gly
                 710                 715                 720

 Trp Val Ser Val Thr Asn Lys Asp Thr Met Asp Ser Lys Thr
                 725                 730

<210> 5569
<211> 1491
<212> DNA
<213> Homo sapien

<400> 5569
 cgagactcca tctcaaaaac aaaacaaata aacgaacaaa aaaacccaca 50

 acgtattatt ttcttgttta cgaggtttct tgtctctctg gctccaccag 100

 aagaggagca gggacccttc ttgctgttgt tcattgctgc atcccccaca 150

 ccgagagcag agcctggcat gggcagaaag tcctcagtcg atatttggtg 200

 gccccaagcg aatgaagcat ccaagaaggg aaagctgggg gctccccact 250

 gcacttgcca cctgagtcac attttcagaa gcctctggaa agtcgtgcac 300

 agcccaggag tgttgagcaa tttcggtttc ctctgaggtt gaaggaccca 350

 ggcgtgtcag ccctgctcca gacaccttgg gcatggagga gagtgtcgta 400

 cggccctcag tgtttgtggt ggatggacag accgacatcc cattcacgag 450

 gctgggacga agccaccgga gacagtcgtg cagtgtggcc cgggtgggtc 500

 tgggtctctt gctgttgctg atgggggccg ggctggccgt ccaaggctgg 550

 ttcctcctgc agctgcactg gcgtctagga gagatggtca cccgcctgcc 600

 tgacggacct gcaggctcct gggagcagct gatacaagag cgaaggtctc 650

 acgaggtcaa cccagcagcg catctcacag gggccaactc cagcttgacc 700

 ggcagcgggg ggccgctgtt atgggagact cagctgggcc tggccttcct 750

 gaggggcctc agctaccacg atggggccct tgtggtcacc aaagctggct 800

 actactacat ctactccaag gtgcagctgg gcggtgtggg ctgcccgctg 850

 ggcctggcca gcaccatcac ccacggcctc tacaagcgca caccccgcta 900

 ccccgaggag ctggagctgt tggtcagcca gcagtcaccc tgcggacggg 950

 ccaccagcag ctcccgggtc tggtgggaca gcagcttcct gggtggtgtg 1000

 gtacacctgg aggctgggga gaaggtggtc gtccgtgtgc tggatgaacg 1050

 cctggttcga ctgcgtgatg gtacccggtc ttacttcggg gctttcatgg 1100

 tgtgaaggaa ggagcgtggt gcattggaca tgggtctgac acgtggagaa 1150

 ctcagagggt gcctcagggg aaagaaaact cacgaagcag aggctgggcg 1200

 tggtggctct cgcctgtaat cccagcactt tgggaggcca aggcaggcgg 1250

 atcacctgag gtcaggagtt cgagaccagc ctggctaaca tggcaaaacc 1300

 ccatctctac taaaaataca aaaattagcc ggacgtggtg gtgcctgcct 1350

 gtaatccagc tactcaggag gctgaggcag gataattttg cttaaacccg 1400

 ggaggcggag gttgcagtga gccgagatca caccactgca ctccaacctg 1450

 ggaaacgcag tgagactgtg cctcaaaaaa aaaaaaaaaa a 1491

<210> 5570
<211> 240
<212> PRT
<213> Homo sapien

<400> 5570
 Met Glu Glu Ser Val Val Arg Pro Ser Val Phe Val Val Asp Gly
   1               5                  10                  15

 Gln Thr Asp Ile Pro Phe Thr Arg Leu Gly Arg Ser His Arg Arg
                  20                  25                  30

 Gln Ser Cys Ser Val Ala Arg Val Gly Leu Gly Leu Leu Leu Leu
                  35                  40                  45

 Leu Met Gly Ala Gly Leu Ala Val Gln Gly Trp Phe Leu Leu Gln
                  50                  55                  60

 Leu His Trp Arg Leu Gly Glu Met Val Thr Arg Leu Pro Asp Gly
                  65                  70                  75

 Pro Ala Gly Ser Trp Glu Gln Leu Ile Gln Glu Arg Arg Ser His
                  80                  85                  90

 Glu Val Asn Pro Ala Ala His Leu Thr Gly Ala Asn Ser Ser Leu
                  95                 100                 105

 Thr Gly Ser Gly Gly Pro Leu Leu Trp Glu Thr Gln Leu Gly Leu
                 110                 115                 120

 Ala Phe Leu Arg Gly Leu Ser Tyr His Asp Gly Ala Leu Val Val
                 125                 130                 135

 Thr Lys Ala Gly Tyr Tyr Tyr Ile Tyr Ser Lys Val Gln Leu Gly
                 140                 145                 150

 Gly Val Gly Cys Pro Leu Gly Leu Ala Ser Thr Ile Thr His Gly
                 155                 160                 165

 Leu Tyr Lys Arg Thr Pro Arg Tyr Pro Glu Glu Leu Glu Leu Leu
                 170                 175                 180

 Val Ser Gln Gln Ser Pro Cys Gly Arg Ala Thr Ser Ser Ser Arg
                 185                 190                 195

 Val Trp Trp Asp Ser Ser Phe Leu Gly Gly Val Val His Leu Glu
                 200                 205                 210

 Ala Gly Glu Lys Val Val Val Arg Val Leu Asp Glu Arg Leu Val
                 215                 220                 225

 Arg Leu Arg Asp Gly Thr Arg Ser Tyr Phe Gly Ala Phe Met Val
                 230                 235                 240

<210> 5571
<211> 1769
<212> DNA
<213> Homo sapien

<400> 5571
 cctcactgac tataaaagaa tagagaagga agggcttcag tgaccggctg 50

 cctggctgac ttacagcagt cagactctga caggatcatg gctatgatgg 100

 aggtccaggg gggacccagc ctgggacaga cctgcgtgct gatcgtgatc 150

 ttcacagtgc tcctgcagtc tctctgtgtg gctgtaactt acgtgtactt 200

 taccaacgag ctgaagcaga tgcaggacaa gtactccaaa agtggcattg 250

 cttgtttctt aaaagaagat gacagttatt gggaccccaa tgacgaagag 300

 agtatgaaca gcccctgctg gcaagtcaag tggcaactcc gtcagctcgt 350

 tagaaagatg attttgagaa cctctgagga aaccatttct acagttcaag 400

 aaaagcaaca aaatatttct cccctagtga gagaaagagg tcctcagaga 450

 gtagcagctc acataactgg gaccagagga agaagcaaca cattgtcttc 500

 tccaaactcc aagaatgaaa aggctctggg ccgcaaaata aactcctggg 550

 aatcatcaag gagtgggcat tcattcctga gcaacttgca cttgaggaat 600

 ggtgaactgg tcatccatga aaaagggttt tactacatct attcccaaac 650

 atactttcga tttcaggagg aaataaaaga aaacacaaag aacgacaaac 700

 aaatggtcca atatatttac aaatacacaa gttatcctga ccctatattg 750

 ttgatgaaaa gtgctagaaa tagttgttgg tctaaagatg cagaatatgg 800

 actctattcc atctatcaag ggggaatatt tgagcttaag gaaaatgaca 850

 gaatttttgt ttctgtaaca aatgagcact tgatagacat ggaccatgaa 900

 gccagttttt tcggggcctt tttagttggc taactgacct ggaaagaaaa 950

 agcaataacc tcaaagtgac tattcagttt tcaggatgat acactatgaa 1000

 gatgtttcaa aaaatctgac caaaacaaac aaacagaaaa cagaaaacaa 1050

 aaaaacctct atgcaatctg agtagagcag ccacaaccaa aaaattctac 1100

 aacacacact gttctgaaag tgactcactt atcccaagaa aatgaaattg 1150

 ctgaaagatc tttcaggact ctacctcata tcagtttgct agcagaaatc 1200

 tagaagactg tcagcttcca aacattaatg caatggttaa catcttctgt 1250

 ctttataatc tactccttgt aaagactgta gaagaaagcg caacaatcca 1300

 tctctcaagt agtgtatcac agtagtagcc tccaggtttc cttaagggac 1350

 aacatcctta agtcaaaaga gagaagaggc accactaaaa gatcgcagtt 1400

 tgcctggtgc agtggctcac acctgtaatc ccaacatttt gggaacccaa 1450

 ggtgggtaga tcacgagatc aagagatcaa gaccatagtg accaacatag 1500

 tgaaacccca tctctactga aagtgcaaaa attagctggg tgtgttggca 1550

 catgcctgta gtcccagcta cttgagaggc tgaggcagga gaatcgtttg 1600

 aacccgggag gcagaggttg cagtgtggtg agatcatgcc actacactcc 1650

 agcctggcga cagagcgaga cttggtttca aaaaaaaaaa aaaaaaaaaa 1700

 cttcagtaag tacgtgttat ttttttcaat aaaattctat tacagtatgt 1750

 caaaaaaaaa aaaaaaaaa 1769

<210> 5572
<211> 281
<212> PRT
<213> Homo sapien

<400> 5572
 Met Ala Met Met Glu Val Gln Gly Gly Pro Ser Leu Gly Gln Thr
   1               5                  10                  15

 Cys Val Leu Ile Val Ile Phe Thr Val Leu Leu Gln Ser Leu Cys
                  20                  25                  30

 Val Ala Val Thr Tyr Val Tyr Phe Thr Asn Glu Leu Lys Gln Met
                  35                  40                  45

 Gln Asp Lys Tyr Ser Lys Ser Gly Ile Ala Cys Phe Leu Lys Glu
                  50                  55                  60

 Asp Asp Ser Tyr Trp Asp Pro Asn Asp Glu Glu Ser Met Asn Ser
                  65                  70                  75

 Pro Cys Trp Gln Val Lys Trp Gln Leu Arg Gln Leu Val Arg Lys
                  80                  85                  90

 Met Ile Leu Arg Thr Ser Glu Glu Thr Ile Ser Thr Val Gln Glu
                  95                 100                 105

 Lys Gln Gln Asn Ile Ser Pro Leu Val Arg Glu Arg Gly Pro Gln
                 110                 115                 120

 Arg Val Ala Ala His Ile Thr Gly Thr Arg Gly Arg Ser Asn Thr
                 125                 130                 135

 Leu Ser Ser Pro Asn Ser Lys Asn Glu Lys Ala Leu Gly Arg Lys
                 140                 145                 150

 Ile Asn Ser Trp Glu Ser Ser Arg Ser Gly His Ser Phe Leu Ser
                 155                 160                 165

 Asn Leu His Leu Arg Asn Gly Glu Leu Val Ile His Glu Lys Gly
                 170                 175                 180

 Phe Tyr Tyr Ile Tyr Ser Gln Thr Tyr Phe Arg Phe Gln Glu Glu
                 185                 190                 195

 Ile Lys Glu Asn Thr Lys Asn Asp Lys Gln Met Val Gln Tyr Ile
                 200                 205                 210

 Tyr Lys Tyr Thr Ser Tyr Pro Asp Pro Ile Leu Leu Met Lys Ser
                 215                 220                 225

 Ala Arg Asn Ser Cys Trp Ser Lys Asp Ala Glu Tyr Gly Leu Tyr
                 230                 235                 240

 Ser Ile Tyr Gln Gly Gly Ile Phe Glu Leu Lys Glu Asn Asp Arg
                 245                 250                 255

 Ile Phe Val Ser Val Thr Asn Glu His Leu Ile Asp Met Asp His
                 260                 265                 270

 Glu Ala Ser Phe Phe Gly Ala Phe Leu Val Gly
                 275                 280

<210> 5573
<211> 3865
<212> DNA
<213> Homo sapien

<400> 5573
 cggcagggtt ggaaaatgat ggaagaggcg gaggtggagg cgaccgagtg 50

 ctgagaggaa cctgcggaat cggccgagat ggggtctggc gcgcgctttc 100

 cctcggggac ccttcgtgtc cggtggttgc tgttgcttgg cctggtgggc 150

 ccagtcctcg gtgcggcgcg gccaggcttt caacagacct cacatctttc 200

 ttcttatgaa attataactc cttggagatt aactagagaa agaagagaag 250

 cccctaggcc ctattcaaaa caagtatctt atgttattca ggctgaagga 300

 aaagagcata ttattcactt ggaaaggaac aaagaccttt tgcctgaaga 350

 ttttgtggtt tatacttaca acaaggaagg gactttaatc actgaccatc 400

 ccaatataca gaatcattgt cattatcggg gctatgtgga gggagttcat 450

 aattcatcca ttgctcttag cgactgtttt ggactcagag gattgctgca 500

 tttagagaat gcgagttatg ggattgaacc cctgcagaac agctctcatt 550

 ttgagcacat catttatcga atggatgatg tctacaaaga gcctctgaaa 600

 tgtggagttt ccaacaagga tatagagaaa gaaactgcaa aggatgaaga 650

 ggaagagcct cccagcatga ctcagctact tcgaagaaga agagctgtct 700

 tgccacagac ccggtatgtg gagctgttca ttgtcgtaga caaggaaagg 750

 tatgacatga tgggaagaaa tcagactgct gtgagagaag agatgattct 800

 cctggcaaac tacttggata gtatgtatat tatgttaaat attcgaattg 850

 tgctagttgg actggagatt tggaccaatg gaaacctgat caacatagtt 900

 gggggtgctg gtgatgtgct ggggaacttc gtgcagtggc gggaaaagtt 950

 tcttatcaca cgtcggagac atgacagtgc acagctagtt ctaaagaaag 1000

 gttttggtgg aactgcagga atggcatttg tgggaacagt gtgttcaagg 1050

 agccacgcag gcgggattaa tgtgtttgga caaatcactg tggagacatt 1100

 tgcttccatt gttgctcatg aattgggtca taatcttgga atgaatcacg 1150

 atgatgggag agattgttcc tgtggagcaa agagctgcat catgaattca 1200

 ggagcatcgg gttccagaaa ctttagcagt tgcagtgcag aggactttga 1250

 gaagttaact ttaaataaag gaggaaactg ccttcttaat attccaaagc 1300

 ctgatgaagc ctatagtgct ccctcctgtg gtaataagtt ggtggacgct 1350

 ggggaagagt gtgactgtgg tactccaaag gaatgtgaat tggacccttg 1400

 ctgcgaagga agtacctgta agcttaaatc atttgctgag tgtgcatatg 1450

 gtgactgttg taaagactgt cggttccttc caggaggtac tttatgccga 1500

 ggaaaaacca gtgagtgtga tgttccagag tactgcaatg gttcttctca 1550

 gttctgtcag ccagatgttt ttattcagaa tggatatcct tgccagaata 1600

 acaaagccta ttgctacaac ggcatgtgcc agtattatga tgctcaatgt 1650

 caagtcatct ttggctcaaa agccaaggct gcccccaaag attgtttcat 1700

 tgaagtgaat tctaaaggtg acagatttgg caattgtggt ttctctggca 1750

 atgaatacaa gaagtgtgcc actgggaatg ctttgtgtgg aaagcttcag 1800

 tgtgagaatg tacaagagat acctgtattt ggaattgtgc ctgctattat 1850

 tcaaacgcct agtcgaggca ccaaatgttg gggtgtggat ttccagctag 1900

 gatcagatgt tccagatcct gggatggtta acgaaggcac aaaatgtggt 1950

 gctggaaaga tctgtagaaa cttccagtgt gtagatgctt ctgttctgaa 2000

 ttatgactgt gatgttcaga aaaagtgtca tggacatggg gtatgtaata 2050

 gcaataagaa ttgtcactgt gaaaatggct gggctccccc aaattgtgag 2100

 actaaaggat acggaggaag tgtggacagt ggacctacat acaatgaaat 2150

 gaatactgca ttgagggacg gacttctggt cttcttcttc ctaattgttc 2200

 cccttattgt ctgtgctatt tttatcttca tcaagaggga tcaactgtgg 2250

 agaagctact tcagaaagaa gagatcacaa acatatgagt cagatggcaa 2300

 aaatcaagca aacccttcta gacagccggg gagtgttcct cgacatgttt 2350

 ctccagtgac acctcccaga gaagttccta tatatgcaaa cagatttgca 2400

 gtaccaacct atgcagccaa gcaacctcag cagttcccat caaggccacc 2450

 tccaccacaa ccgaaagtat catctcaggg aaacttaatt cctgcccgtc 2500

 ctgctcctgc acctccttta tatagttccc tcacttgatt tttttaacct 2550

 tctttttgca aatgtcttca gggaactgag ctaatacttt ttttttttct 2600

 tgatgttttc ttgaaaagcc tttctgttgc aactatgaat gaaaacaaaa 2650

 caccacaaaa cagacttcac taacacagaa aaacagaaac tgagtgtgag 2700

 agttgtgaaa tacaaggaaa tgcagtaaag ccagggaatt tacaataaca 2750

 tttccgtttc catcattgaa taagtcttat tcagtcatcg gtgaggttaa 2800

 tgcactaatc atggattttt tgaacatgtt attgcagtga ttctcaaatt 2850

 aactgtattg gtgtaagatt tttgtcatta agtgtttaag tgttattctg 2900

 aattttctac cttagttatc attaatgtag ttcctcattg aacatgtgat 2950

 aatctaatac ctgtgaaaac tgactaatca gctgccaata atatctaata 3000

 tttttcatca tgcacgaatt aataatcatc atactctaga atcttgtctg 3050

 tcactcacta catgaataag caaatattgt cttcaaaaga atgcacaaga 3100

 accacaatta agatgtcata ttattttgaa agtacaaaat atactaaaag 3150

 agtgtgtgtg tattcacgca gttactcgct tccattttta tgacctttca 3200

 actataggta ataactctta gagaaattaa tttaatatta gaatttctat 3250

 tatgaatcat gtgaaagcat gacattcgtt cacaatagca ctattttaaa 3300

 taaattataa gctttaaggt acgaagtatt taatagatct aatcaaatat 3350

 gttgattcat ggctataata aagcaggagc aattataaaa tcttcaatca 3400

 attgaacttt tacaaaacca cttgagaatt tcatgagcac tttaaaatct 3450

 gaactttcaa agcttgctat taaatcattt agaatgttta catttactaa 3500

 ggtgtgctgg gtcatgtaaa atattagaca ctaatatttt catagaaatt 3550

 aggctggaga aagaaggaag aaatggtttt cttaaatacc tacaaaaaag 3600

 ttactgtggt atctatgagt tatcatctta gctgtgttaa aaatgaattt 3650

 ttactatggc agatatggta tggatcgtaa aattttaagc actaaaaatt 3700

 ttttcataac ctttcataat aaagtttaat aataggttta ttaactgaat 3750

 ttcattagtt ttttaaaagt gtttttggtt tgtgtatata tacatataca 3800

 aatacaacat ttacaataaa taaaatactt gaaattctca aaaaaaaaaa 3850

 aaaaaaaaaa aaaaa 3865

<210> 5574
<211> 819
<212> PRT
<213> Homo sapien

<400> 5574
 Met Gly Ser Gly Ala Arg Phe Pro Ser Gly Thr Leu Arg Val Arg
   1               5                  10                  15

 Trp Leu Leu Leu Leu Gly Leu Val Gly Pro Val Leu Gly Ala Ala
                  20                  25                  30

 Arg Pro Gly Phe Gln Gln Thr Ser His Leu Ser Ser Tyr Glu Ile
                  35                  40                  45

 Ile Thr Pro Trp Arg Leu Thr Arg Glu Arg Arg Glu Ala Pro Arg
                  50                  55                  60

 Pro Tyr Ser Lys Gln Val Ser Tyr Val Ile Gln Ala Glu Gly Lys
                  65                  70                  75

 Glu His Ile Ile His Leu Glu Arg Asn Lys Asp Leu Leu Pro Glu
                  80                  85                  90

 Asp Phe Val Val Tyr Thr Tyr Asn Lys Glu Gly Thr Leu Ile Thr
                  95                 100                 105

 Asp His Pro Asn Ile Gln Asn His Cys His Tyr Arg Gly Tyr Val
                 110                 115                 120

 Glu Gly Val His Asn Ser Ser Ile Ala Leu Ser Asp Cys Phe Gly
                 125                 130                 135

 Leu Arg Gly Leu Leu His Leu Glu Asn Ala Ser Tyr Gly Ile Glu
                 140                 145                 150

 Pro Leu Gln Asn Ser Ser His Phe Glu His Ile Ile Tyr Arg Met
                 155                 160                 165

 Asp Asp Val Tyr Lys Glu Pro Leu Lys Cys Gly Val Ser Asn Lys
                 170                 175                 180

 Asp Ile Glu Lys Glu Thr Ala Lys Asp Glu Glu Glu Glu Pro Pro
                 185                 190                 195

 Ser Met Thr Gln Leu Leu Arg Arg Arg Arg Ala Val Leu Pro Gln
                 200                 205                 210

 Thr Arg Tyr Val Glu Leu Phe Ile Val Val Asp Lys Glu Arg Tyr
                 215                 220                 225

 Asp Met Met Gly Arg Asn Gln Thr Ala Val Arg Glu Glu Met Ile
                 230                 235                 240

 Leu Leu Ala Asn Tyr Leu Asp Ser Met Tyr Ile Met Leu Asn Ile
                 245                 250                 255

 Arg Ile Val Leu Val Gly Leu Glu Ile Trp Thr Asn Gly Asn Leu
                 260                 265                 270

 Ile Asn Ile Val Gly Gly Ala Gly Asp Val Leu Gly Asn Phe Val
                 275                 280                 285

 Gln Trp Arg Glu Lys Phe Leu Ile Thr Arg Arg Arg His Asp Ser
                 290                 295                 300

 Ala Gln Leu Val Leu Lys Lys Gly Phe Gly Gly Thr Ala Gly Met
                 305                 310                 315

 Ala Phe Val Gly Thr Val Cys Ser Arg Ser His Ala Gly Gly Ile
                 320                 325                 330

 Asn Val Phe Gly Gln Ile Thr Val Glu Thr Phe Ala Ser Ile Val
                 335                 340                 345

 Ala His Glu Leu Gly His Asn Leu Gly Met Asn His Asp Asp Gly
                 350                 355                 360

 Arg Asp Cys Ser Cys Gly Ala Lys Ser Cys Ile Met Asn Ser Gly
                 365                 370                 375

 Ala Ser Gly Ser Arg Asn Phe Ser Ser Cys Ser Ala Glu Asp Phe
                 380                 385                 390

 Glu Lys Leu Thr Leu Asn Lys Gly Gly Asn Cys Leu Leu Asn Ile
                 395                 400                 405

 Pro Lys Pro Asp Glu Ala Tyr Ser Ala Pro Ser Cys Gly Asn Lys
                 410                 415                 420

 Leu Val Asp Ala Gly Glu Glu Cys Asp Cys Gly Thr Pro Lys Glu
                 425                 430                 435

 Cys Glu Leu Asp Pro Cys Cys Glu Gly Ser Thr Cys Lys Leu Lys
                 440                 445                 450

 Ser Phe Ala Glu Cys Ala Tyr Gly Asp Cys Cys Lys Asp Cys Arg
                 455                 460                 465

 Phe Leu Pro Gly Gly Thr Leu Cys Arg Gly Lys Thr Ser Glu Cys
                 470                 475                 480

 Asp Val Pro Glu Tyr Cys Asn Gly Ser Ser Gln Phe Cys Gln Pro
                 485                 490                 495

 Asp Val Phe Ile Gln Asn Gly Tyr Pro Cys Gln Asn Asn Lys Ala
                 500                 505                 510

 Tyr Cys Tyr Asn Gly Met Cys Gln Tyr Tyr Asp Ala Gln Cys Gln
                 515                 520                 525

 Val Ile Phe Gly Ser Lys Ala Lys Ala Ala Pro Lys Asp Cys Phe
                 530                 535                 540

 Ile Glu Val Asn Ser Lys Gly Asp Arg Phe Gly Asn Cys Gly Phe
                 545                 550                 555

 Ser Gly Asn Glu Tyr Lys Lys Cys Ala Thr Gly Asn Ala Leu Cys
                 560                 565                 570

 Gly Lys Leu Gln Cys Glu Asn Val Gln Glu Ile Pro Val Phe Gly
                 575                 580                 585

 Ile Val Pro Ala Ile Ile Gln Thr Pro Ser Arg Gly Thr Lys Cys
                 590                 595                 600

 Trp Gly Val Asp Phe Gln Leu Gly Ser Asp Val Pro Asp Pro Gly
                 605                 610                 615

 Met Val Asn Glu Gly Thr Lys Cys Gly Ala Gly Lys Ile Cys Arg
                 620                 625                 630

 Asn Phe Gln Cys Val Asp Ala Ser Val Leu Asn Tyr Asp Cys Asp
                 635                 640                 645

 Val Gln Lys Lys Cys His Gly His Gly Val Cys Asn Ser Asn Lys
                 650                 655                 660

 Asn Cys His Cys Glu Asn Gly Trp Ala Pro Pro Asn Cys Glu Thr
                 665                 670                 675

 Lys Gly Tyr Gly Gly Ser Val Asp Ser Gly Pro Thr Tyr Asn Glu
                 680                 685                 690

 Met Asn Thr Ala Leu Arg Asp Gly Leu Leu Val Phe Phe Phe Leu
                 695                 700                 705

 Ile Val Pro Leu Ile Val Cys Ala Ile Phe Ile Phe Ile Lys Arg
                 710                 715                 720

 Asp Gln Leu Trp Arg Ser Tyr Phe Arg Lys Lys Arg Ser Gln Thr
                 725                 730                 735

 Tyr Glu Ser Asp Gly Lys Asn Gln Ala Asn Pro Ser Arg Gln Pro
                 740                 745                 750

 Gly Ser Val Pro Arg His Val Ser Pro Val Thr Pro Pro Arg Glu
                 755                 760                 765

 Val Pro Ile Tyr Ala Asn Arg Phe Ala Val Pro Thr Tyr Ala Ala
                 770                 775                 780

 Lys Gln Pro Gln Gln Phe Pro Ser Arg Pro Pro Pro Pro Gln Pro
                 785                 790                 795

 Lys Val Ser Ser Gln Gly Asn Leu Ile Pro Ala Arg Pro Ala Pro
                 800                 805                 810

 Ala Pro Pro Leu Tyr Ser Ser Leu Thr
                 815

<210> 5575
<211> 3133
<212> DNA
<213> Homo sapien

<400> 5575
 ccgctgaggc cgcggcgccc gccagcctgt cccgcgccat ggccccgcgc 50

 gcccggcggc gccgcccgct gttcgcgctg ctgctgctct gcgcgctgct 100

 cgcccggctg caggtggctt tgcagatcgc tcctccatgt accagtgaga 150

 agcattatga gcatctggga cggtgctgta acaaatgtga accaggaaag 200

 tacatgtctt ctaaatgcac tactacctct gacagtgtat gtctgccctg 250

 tggcccggat gaatacttgg atagctggaa tgaagaagat aaatgcttgc 300

 tgcataaagt ttgtgataca ggcaaggccc tggtggccgt ggtcgccggc 350

 aacagcacga ccccccggcg ctgcgcgtgc acggctgggt accactggag 400

 ccaggactgc gagtgctgcc gccgcaacac cgagtgcgcg ccgggcctgg 450

 gcgcccagca cccgttgcag ctcaacaagg acacagtgtg caaaccttgc 500

 cttgcaggct acttctctga tgccttttcc tccacggaca aatgcagacc 550

 ctggaccaac tgtaccttcc ttggaaagag agtagaacat catgggacag 600

 agaaatccga tgcggtttgc agttcttctc tgccagctag aaaaccacca 650

 aatgaacccc atgtttactt gcccggttta ataattctgc ttctcttcgc 700

 gtctgtggcc ctggtggctg ccatcatctt tggcgtttgc tataggaaaa 750

 aagggaaagc actcacagct aatttgtggc actggatcaa tgaggcttgt 800

 ggccgcctaa gtggagataa ggagtcctca ggtgacagtt gtgtcagtac 850

 acacacggca aactttggtc agcagggagc atgtgaaggt gtcttactgc 900

 tgactctgga ggagaagaca tttccagaag atatgtgcta cccagatcaa 950

 ggtggtgtct gtcagggcac atgtgtagga ggtggtccct acgcacaagg 1000

 cgaagatgcc aggatgctct cattggtcag caagaccgag atagaggaag 1050

 acagcttcag acagatgccc acagaagatg aatacatgga caggccctcc 1100

 cagcccacag accagttact gttcctcact gagcctggaa gcaaatccac 1150

 acctcctttc tctgaacccc tggaggtggg ggagaatgac agtttaagcc 1200

 agtgcttcac ggggacacag agcacagtgg gttcagaaag ctgcaactgc 1250

 actgagcccc tgtgcaggac tgattggact cccatgtcct ctgaaaacta 1300

 cttgcaaaaa gaggtggaca gtggccattg cccgcactgg gcagccagcc 1350

 ccagccccaa ctgggcagat gtctgcacag gctgccggaa ccctcctggg 1400

 gaggactgtg aacccctcgt gggttcccca aaacgtggac ccttgcccca 1450

 gtgcgcctat ggcatgggcc ttccccctga agaagaagcc agcaggacgg 1500

 aggccagaga ccagcccgag gatggggctg atgggaggct cccaagctca 1550

 gcgagggcag gtgccgggtc tggaagctcc cctggtggcc agtcccctgc 1600

 atctggaaat gtgactggaa acagtaactc cacgttcatc tccagcgggc 1650

 aggtgatgaa cttcaagggc gacatcatcg tggtctacgt cagccagacc 1700

 tcgcaggagg gcgcggcggc ggctgcggag cccatgggcc gcccggtgca 1750

 ggaggagacc ctggcgcgcc gagactcctt cgcggggaac ggcccgcgct 1800

 tcccggaccc gtgcggcggc cccgaggggc tgcgggagcc ggagaaggcc 1850

 tcgaggccgg tgcaggagca aggcggggcc aaggcttgag cgccccccat 1900

 ggctgggagc ccgaagctcg gagccagggc tcgcgagggc agcaccgcag 1950

 cctctgcccc agccccggcc acccagggat cgatcggtac agtcgaggaa 2000

 gaccacccgg cattctctgc ccactttgcc ttccaggaaa tgggcttttc 2050

 aggaagtgaa ttgatgagga ctgtccccat gcccacggat gctcagcagc 2100

 ccgccgcact ggggcagatg tctcccctgc cactcctcaa actcgcagca 2150

 gtaatttgtg gcactatgac agctattttt atgactatcc tgttctgtgg 2200

 gggggggggt ctgttttccc cccatatttg tattcctttt cataactttt 2250

 cttgatatct ttcctccctc ttttttaatg taaaggtttt ctcaaaaatt 2300

 ctcctaaagg tgagggtctc tttcttttct cttttccttt tttttttctt 2350

 tttttggcaa cctggctctg gcccaggcta gagtgcagtg gtgcgattat 2400

 agcccggtgc agcctctaac tcctgggctc aagcaatcca agtgatcctc 2450

 ccacctcaac cttcggagta gctgggatca cagctgcagg ccacgcccag 2500

 cttcctcccc ccgactcccc ccccagagac acggtcccac catgttaccc 2550

 agcctggtct caaactcccc agctaaagca gtcctccagc ctcggcctcc 2600

 caaagtactg ggattacagg cgtgagcccc cacgctggcc tgctttacgt 2650

 attttctttt gtgcccctgc tcacagtgtt ttagagatgg ctttcccagt 2700

 gtgtgttcat tgtaaacact tttgggaaag ggctaaacat gtgaggcctg 2750

 gagatagttg ctaagttgct aggaacatgt ggtgggactt tcatattctg 2800

 aaaaatgttc tatattctca tttttctaaa agaaagaaaa aaggaaaccc 2850

 gatttatttc tcctgaatct ttttaagttt gtgtcgttcc ttaagcagaa 2900

 ctaagctcag tatgtgacct tacccgctag gtggttaatt tatccatgct 2950

 ggcagaggca ctcaggtact tggtaagcaa atttctaaaa ctccaagttg 3000

 ctgcagcttg gcattcttct tattctagag gtctctctgg aaaagatgga 3050

 gaaaatgaac aggacatggg gctcctggaa agaaagggcc cgggaagttc 3100

 aaggaagaat aaagttgaaa ttttaaaaaa aaa 3133

<210> 5576
<211> 616
<212> PRT
<213> Homo sapien

<400> 5576
 Met Ala Pro Arg Ala Arg Arg Arg Arg Pro Leu Phe Ala Leu Leu
   1               5                  10                  15

 Leu Leu Cys Ala Leu Leu Ala Arg Leu Gln Val Ala Leu Gln Ile
                  20                  25                  30

 Ala Pro Pro Cys Thr Ser Glu Lys His Tyr Glu His Leu Gly Arg
                  35                  40                  45

 Cys Cys Asn Lys Cys Glu Pro Gly Lys Tyr Met Ser Ser Lys Cys
                  50                  55                  60

 Thr Thr Thr Ser Asp Ser Val Cys Leu Pro Cys Gly Pro Asp Glu
                  65                  70                  75

 Tyr Leu Asp Ser Trp Asn Glu Glu Asp Lys Cys Leu Leu His Lys
                  80                  85                  90

 Val Cys Asp Thr Gly Lys Ala Leu Val Ala Val Val Ala Gly Asn
                  95                 100                 105

 Ser Thr Thr Pro Arg Arg Cys Ala Cys Thr Ala Gly Tyr His Trp
                 110                 115                 120

 Ser Gln Asp Cys Glu Cys Cys Arg Arg Asn Thr Glu Cys Ala Pro
                 125                 130                 135

 Gly Leu Gly Ala Gln His Pro Leu Gln Leu Asn Lys Asp Thr Val
                 140                 145                 150

 Cys Lys Pro Cys Leu Ala Gly Tyr Phe Ser Asp Ala Phe Ser Ser
                 155                 160                 165

 Thr Asp Lys Cys Arg Pro Trp Thr Asn Cys Thr Phe Leu Gly Lys
                 170                 175                 180

 Arg Val Glu His His Gly Thr Glu Lys Ser Asp Ala Val Cys Ser
                 185                 190                 195

 Ser Ser Leu Pro Ala Arg Lys Pro Pro Asn Glu Pro His Val Tyr
                 200                 205                 210

 Leu Pro Gly Leu Ile Ile Leu Leu Leu Phe Ala Ser Val Ala Leu
                 215                 220                 225

 Val Ala Ala Ile Ile Phe Gly Val Cys Tyr Arg Lys Lys Gly Lys
                 230                 235                 240

 Ala Leu Thr Ala Asn Leu Trp His Trp Ile Asn Glu Ala Cys Gly
                 245                 250                 255

 Arg Leu Ser Gly Asp Lys Glu Ser Ser Gly Asp Ser Cys Val Ser
                 260                 265                 270

 Thr His Thr Ala Asn Phe Gly Gln Gln Gly Ala Cys Glu Gly Val
                 275                 280                 285

 Leu Leu Leu Thr Leu Glu Glu Lys Thr Phe Pro Glu Asp Met Cys
                 290                 295                 300

 Tyr Pro Asp Gln Gly Gly Val Cys Gln Gly Thr Cys Val Gly Gly
                 305                 310                 315

 Gly Pro Tyr Ala Gln Gly Glu Asp Ala Arg Met Leu Ser Leu Val
                 320                 325                 330

 Ser Lys Thr Glu Ile Glu Glu Asp Ser Phe Arg Gln Met Pro Thr
                 335                 340                 345

 Glu Asp Glu Tyr Met Asp Arg Pro Ser Gln Pro Thr Asp Gln Leu
                 350                 355                 360

 Leu Phe Leu Thr Glu Pro Gly Ser Lys Ser Thr Pro Pro Phe Ser
                 365                 370                 375

 Glu Pro Leu Glu Val Gly Glu Asn Asp Ser Leu Ser Gln Cys Phe
                 380                 385                 390

 Thr Gly Thr Gln Ser Thr Val Gly Ser Glu Ser Cys Asn Cys Thr
                 395                 400                 405

 Glu Pro Leu Cys Arg Thr Asp Trp Thr Pro Met Ser Ser Glu Asn
                 410                 415                 420

 Tyr Leu Gln Lys Glu Val Asp Ser Gly His Cys Pro His Trp Ala
                 425                 430                 435

 Ala Ser Pro Ser Pro Asn Trp Ala Asp Val Cys Thr Gly Cys Arg
                 440                 445                 450

 Asn Pro Pro Gly Glu Asp Cys Glu Pro Leu Val Gly Ser Pro Lys
                 455                 460                 465

 Arg Gly Pro Leu Pro Gln Cys Ala Tyr Gly Met Gly Leu Pro Pro
                 470                 475                 480

 Glu Glu Glu Ala Ser Arg Thr Glu Ala Arg Asp Gln Pro Glu Asp
                 485                 490                 495

 Gly Ala Asp Gly Arg Leu Pro Ser Ser Ala Arg Ala Gly Ala Gly
                 500                 505                 510

 Ser Gly Ser Ser Pro Gly Gly Gln Ser Pro Ala Ser Gly Asn Val
                 515                 520                 525

 Thr Gly Asn Ser Asn Ser Thr Phe Ile Ser Ser Gly Gln Val Met
                 530                 535                 540

 Asn Phe Lys Gly Asp Ile Ile Val Val Tyr Val Ser Gln Thr Ser
                 545                 550                 555

 Gln Glu Gly Ala Ala Ala Ala Ala Glu Pro Met Gly Arg Pro Val
                 560                 565                 570

 Gln Glu Glu Thr Leu Ala Arg Arg Asp Ser Phe Ala Gly Asn Gly
                 575                 580                 585

 Pro Arg Phe Pro Asp Pro Cys Gly Gly Pro Glu Gly Leu Arg Glu
                 590                 595                 600

 Pro Glu Lys Ala Ser Arg Pro Val Gln Glu Gln Gly Gly Ala Lys
                 605                 610                 615

 Ala


<210> 5577
<211> 2668
<212> DNA
<213> Homo sapien

<400> 5577
 ctctctggat aggaagaaat atagtagaac cctttgaaaa tggatatttt 50

 cacatatttt cgttcagata caaaagctgg cagttactga aataaggact 100

 tgaagttcct tcctcttttt tttatgtctt aagagcagga aataaagaga 150

 cagctgaagg tgtagccttg accaactgaa agggaaatct tcatcctctg 200

 aaaaaacata tgtgattctc aaaaaacgca tctggaaaat tgataaagaa 250

 gcgattctgt agattctccc agcgctgttg ggctctcaat tccttctgtg 300

 aaggacaaca tatggtgatg gggaaatcag aagctttgag accctctaca 350

 cctggatatg aatccccctt ctaatactta ccagaaatga aggggatact 400

 cagggcagag ttctgaatct caaaacactc tactctggca aaggaatgaa 450

 gttattggag tgatgacagg aacacgggag aacaatgctc tgtttgggct 500

 ggatatttct ttggcttgtt gcaggagagc gaattaaagg atttaatatt 550

 tcaggttgtt ccacaaaaaa actcctttgg acatattcta caaggagtga 600

 agaggaattt gtcttatttt gtgatttacc agagccacag aaatcacatt 650

 tctgccacag aaatcgactc tcaccaaaac aagtccctga gcacctgccc 700

 ttcatgggta gtaacgacct atctgatgtc caatggtacc aacaaccttc 750

 gaatggagat ccattagagg acattaggaa aagctatcct cacatcattc 800

 aggacaaatg tacccttcac tttttgaccc caggggtgaa taattctggg 850

 tcatatattt gtagacccaa gatgattaag agcccctatg atgtagcctg 900

 ttgtgtcaag atgattttag aagttaagcc ccagacaaat gcatcctgtg 950

 agtattccgc atcacataag caagacctac ttcttgggag cactggctct 1000

 atttcttgcc ccagtctcag ctgccaaagt gatgcacaaa gtccagcggt 1050

 aacctggtac aagaatggaa aactcctctc tgtggaaagg agcaaccgaa 1100

 tcgtagtgga tgaagtttat gactatcacc agggcacata tgtatgtgat 1150

 tacactcagt cggatactgt gagttcgtgg acagtcagag ctgttgttca 1200

 agtgagaacc attgtgggag acactaaact caaaccagat attctggatc 1250

 ctgtcgagga cacactggaa gtagaacttg gaaagccttt aactattagc 1300

 tgcaaagcac gatttggctt tgaaagggtc tttaaccctg tcataaaatg 1350

 gtacatcaaa gattctgacc tagagtggga agtctcagta cctgaggcga 1400

 aaagtattaa atccacttta aaggatgaaa tcattgagcg taatatcatc 1450

 ttggaaaaag tcactcagcg tgatcttcgc aggaagtttg tttgctttgt 1500

 ccagaactcc attggaaaca caacccagtc cgtccaactg aaagaaaaga 1550

 gaggagtggt gctcctgtac atcctgcttg gcaccatcgg gaccctggtg 1600

 gccgtgctgg cggcgagtgc cctcctctac aggcactgga ttgaaatagt 1650

 gctgctgtac cggacctacc agagcaagga tcagacgctt ggggataaaa 1700

 aggattttga tgctttcgta tcctatgcaa aatggagctc ttttccaagt 1750

 gaggccactt catctctgag tgaagaacac ttggccctga gcctatttcc 1800

 tgatgtttta gaaaacaaat atggatatag cctgtgtttg cttgaaagag 1850

 atgtggctcc aggaggagtg tatgcagaag acattgtgag cattattaag 1900

 agaagcagaa gaggaatatt tatcttgagc cccaactatg tcaatggacc 1950

 cagtatcttt gaactacaag cagcagtgaa tcttgccttg gatgatcaaa 2000

 cactgaaact cattttaatt aagttctgtt acttccaaga gccagagtct 2050

 ctacctcatc tcgtgaaaaa agctctcagg gttttgccca cagttacttg 2100

 gagaggctta aaatcagttc ctcccaattc taggttctgg gccaaaatgc 2150

 gctaccacat gcctgtgaaa aactctcagg gattcacgtg gaaccagctc 2200

 agaattacct ctaggatttt tcagtggaaa ggactcagta gaacagaaac 2250

 cactgggagg agctcccagc ctaaggaatg gtgaaatgag ccctggagcc 2300

 ccctccagtc cagtccctgg gatagagatg ttgctggaca gaactcacag 2350

 ctctgtgtgt gtgtgttcag gctgatagga aattcaaaga gtctcctgcc 2400

 agcaccaagc aagcttgatg gacaatggag tgggattgag actgtggttt 2450

 agagcctttg atttcctgga ctggactgac ggcgagtgaa ttctctagac 2500

 cttgggtact ttcagtacac aacaccccta agatttccca gtggtccgag 2550

 cagaatcaga aaatacagct acttctgcct tatggctagg gaactgtcat 2600

 gtctaccatg tattgtacat atgactttat gtatacttgc aatcaaataa 2650

 atattatttt attagaaa 2668

<210> 5578
<211> 599
<212> PRT
<213> Homo sapien

<400> 5578
 Met Leu Cys Leu Gly Trp Ile Phe Leu Trp Leu Val Ala Gly Glu
   1               5                  10                  15

 Arg Ile Lys Gly Phe Asn Ile Ser Gly Cys Ser Thr Lys Lys Leu
                  20                  25                  30

 Leu Trp Thr Tyr Ser Thr Arg Ser Glu Glu Glu Phe Val Leu Phe
                  35                  40                  45

 Cys Asp Leu Pro Glu Pro Gln Lys Ser His Phe Cys His Arg Asn
                  50                  55                  60

 Arg Leu Ser Pro Lys Gln Val Pro Glu His Leu Pro Phe Met Gly
                  65                  70                  75

 Ser Asn Asp Leu Ser Asp Val Gln Trp Tyr Gln Gln Pro Ser Asn
                  80                  85                  90

 Gly Asp Pro Leu Glu Asp Ile Arg Lys Ser Tyr Pro His Ile Ile
                  95                 100                 105

 Gln Asp Lys Cys Thr Leu His Phe Leu Thr Pro Gly Val Asn Asn
                 110                 115                 120

 Ser Gly Ser Tyr Ile Cys Arg Pro Lys Met Ile Lys Ser Pro Tyr
                 125                 130                 135

 Asp Val Ala Cys Cys Val Lys Met Ile Leu Glu Val Lys Pro Gln
                 140                 145                 150

 Thr Asn Ala Ser Cys Glu Tyr Ser Ala Ser His Lys Gln Asp Leu
                 155                 160                 165

 Leu Leu Gly Ser Thr Gly Ser Ile Ser Cys Pro Ser Leu Ser Cys
                 170                 175                 180

 Gln Ser Asp Ala Gln Ser Pro Ala Val Thr Trp Tyr Lys Asn Gly
                 185                 190                 195

 Lys Leu Leu Ser Val Glu Arg Ser Asn Arg Ile Val Val Asp Glu
                 200                 205                 210

 Val Tyr Asp Tyr His Gln Gly Thr Tyr Val Cys Asp Tyr Thr Gln
                 215                 220                 225

 Ser Asp Thr Val Ser Ser Trp Thr Val Arg Ala Val Val Gln Val
                 230                 235                 240

 Arg Thr Ile Val Gly Asp Thr Lys Leu Lys Pro Asp Ile Leu Asp
                 245                 250                 255

 Pro Val Glu Asp Thr Leu Glu Val Glu Leu Gly Lys Pro Leu Thr
                 260                 265                 270

 Ile Ser Cys Lys Ala Arg Phe Gly Phe Glu Arg Val Phe Asn Pro
                 275                 280                 285

 Val Ile Lys Trp Tyr Ile Lys Asp Ser Asp Leu Glu Trp Glu Val
                 290                 295                 300

 Ser Val Pro Glu Ala Lys Ser Ile Lys Ser Thr Leu Lys Asp Glu
                 305                 310                 315

 Ile Ile Glu Arg Asn Ile Ile Leu Glu Lys Val Thr Gln Arg Asp
                 320                 325                 330

 Leu Arg Arg Lys Phe Val Cys Phe Val Gln Asn Ser Ile Gly Asn
                 335                 340                 345

 Thr Thr Gln Ser Val Gln Leu Lys Glu Lys Arg Gly Val Val Leu
                 350                 355                 360

 Leu Tyr Ile Leu Leu Gly Thr Ile Gly Thr Leu Val Ala Val Leu
                 365                 370                 375

 Ala Ala Ser Ala Leu Leu Tyr Arg His Trp Ile Glu Ile Val Leu
                 380                 385                 390

 Leu Tyr Arg Thr Tyr Gln Ser Lys Asp Gln Thr Leu Gly Asp Lys
                 395                 400                 405

 Lys Asp Phe Asp Ala Phe Val Ser Tyr Ala Lys Trp Ser Ser Phe
                 410                 415                 420

 Pro Ser Glu Ala Thr Ser Ser Leu Ser Glu Glu His Leu Ala Leu
                 425                 430                 435

 Ser Leu Phe Pro Asp Val Leu Glu Asn Lys Tyr Gly Tyr Ser Leu
                 440                 445                 450

 Cys Leu Leu Glu Arg Asp Val Ala Pro Gly Gly Val Tyr Ala Glu
                 455                 460                 465

 Asp Ile Val Ser Ile Ile Lys Arg Ser Arg Arg Gly Ile Phe Ile
                 470                 475                 480

 Leu Ser Pro Asn Tyr Val Asn Gly Pro Ser Ile Phe Glu Leu Gln
                 485                 490                 495

 Ala Ala Val Asn Leu Ala Leu Asp Asp Gln Thr Leu Lys Leu Ile
                 500                 505                 510

 Leu Ile Lys Phe Cys Tyr Phe Gln Glu Pro Glu Ser Leu Pro His
                 515                 520                 525

 Leu Val Lys Lys Ala Leu Arg Val Leu Pro Thr Val Thr Trp Arg
                 530                 535                 540

 Gly Leu Lys Ser Val Pro Pro Asn Ser Arg Phe Trp Ala Lys Met
                 545                 550                 555

 Arg Tyr His Met Pro Val Lys Asn Ser Gln Gly Phe Thr Trp Asn
                 560                 565                 570

 Gln Leu Arg Ile Thr Ser Arg Ile Phe Gln Trp Lys Gly Leu Ser
                 575                 580                 585

 Arg Thr Glu Thr Thr Gly Arg Ser Ser Gln Pro Lys Glu Trp
                 590                 595

<210> 5579
<211> 3522
<212> DNA
<213> Homo sapien

<400> 5579
 gccatttgaa gcagaatcca aaccatgaat tgtagagaat tacccttgac 50

 cctttgggtg cttatatctg taagcactgc agaatcttgt acttcacgtc 100

 cccacattac tgtggttgaa ggggaacctt tctatctgaa acattgctcg 150

 tgttcacttg cacatgagat tgaaacaacc accaaaagct ggtacaaaag 200

 cagtggatca caggaacatg tggagctgaa cccaaggagt tcctcgagaa 250

 ttgctttgca tgattgtgtt ttggagtttt ggccagttga gttgaatgac 300

 acaggatctt actttttcca aatgaaaaat tatactcaga aatggaaatt 350

 aaatgtcatc agaagaaata aacacagctg tttcactgaa agacaagtaa 400

 ctagtaaaat tgtggaagtt aaaaaatttt ttcagataac ctgtgaaaac 450

 agttactatc aaacactggt caacagcaca tcattgtata agaactgtaa 500

 aaagctacta ctggagaaca ataaaaaccc aacgataaag aagaacgccg 550

 agtttgaaga tcaggggtat tactcctgcg tgcatttcct tcatcataat 600

 ggaaaactat ttaatatcac caaaaccttc aatataacaa tagtggaaga 650

 tcgcagtaat atagttccgg ttcttcttgg accaaagctt aaccatgttg 700

 cagtggaatt aggaaaaaac gtaaggctca actgctctgc tttgctgaat 750

 gaagaggatg taatttattg gatgttcggg gaagaaaatg gatcggatcc 800

 taatatacat gaagagaaag aaatgagaat tatgactcca gaaggcaaat 850

 ggcatgcttc aaaagtattg agaattgaaa atattggtga aagcaatcta 900

 aatgttttat ataattgcac tgtggccagc acgggaggca cagacaccaa 950

 aagcttcatc ttggtgagaa aagcagacat ggctgatatc ccaggccacg 1000

 tcttcacaag aggaatgatc atagctgttt tgatcttggt ggcagtagtg 1050

 tgcctagtga ctgtgtgtgt catttataga gttgacttgg ttctatttta 1100

 tagacattta acgagaagag atgaaacatt aacagatgga aaaacatatg 1150

 atgcttttgt gtcttaccta aaagaatgcc gacctgaaaa tggagaggag 1200

 cacacctttg ctgtggagat tttgcccagg gtgttggaga aacattttgg 1250

 gtataagtta tgcatatttg aaagggatgt agtgcctgga ggagctgttg 1300

 ttgatgaaat ccactcactg atagagaaaa gccgaagact aatcattgtc 1350

 ctaagtaaaa gttatatgtc taatgaggtc aggtatgaac ttgaaagtgg 1400

 actccatgaa gcattggtgg aaagaaaaat taaaataatc ttaattgaat 1450

 ttacacctgt tactgacttc acattcttgc cccaatcact aaagcttttg 1500

 aaatctcaca gagttctgaa gtggaaggcc gataaatctc tttcttataa 1550

 ctcaaggttc tggaagaacc ttctttactt aatgcctgca aaaacagtca 1600

 agccaggtag agacgaaccg gaagtcttgc ctgttctttc cgagtcttaa 1650

 tcttcagaaa cagtgaacgc caaaaagaac tcaagatatt ctggggactg 1700

 agcatatgaa cctgttcata acaaaggctg tgactcgaaa taattaactt 1750

 tgtcaaaatc ctgctcacaa tttgaagatg aaacttgtca ttaggttggc 1800

 gggaatgaga ctaaagattg cgctgtgggc tgtggtcacg tgctcccaga 1850

 agacctggaa ttcaaaagaa atggagctat tctttttctc cctctttcat 1900

 aactggatgc agctgctcat actcaatccc atattcagca agtgtgaagc 1950

 tggacgtgat gcaaaataac cgatgcccta caaaaagggc gcatctttaa 2000

 gagttttaat gccagtgctt aattcgaatg aggggatttt aagtgtctga 2050

 agaggcattt tctagggacc agtgggtgac tgagtaactg aaatgctgct 2100

 ttcactccct aacaccatgg atctggttgt gcataggatg tgggaggagg 2150

 ggctggcagg gccgccttca gaggctgcag ggcctcagcc tcaggatgca 2200

 tttaatgtat cctggccaca gttgcagcca acggttcttg aaagctcggt 2250

 aaggccctgc aacgcagagc ctgcttatgt ggatctattt atgggaactt 2300

 cttaaaagga ccccagaata gctctttatc tttcacaaga gacacaaatt 2350

 ctaattgagt taattatctg ggcctttcac tttggatgct ctgaaacatt 2400

 tgttgatttt gtgtgaatgt ttatatcaaa atgtttgcca ggttgtatta 2450

 gccattgaat agcaaaaaac tgatagttac ttgcttgttt tttaaaaatt 2500

 acatattaaa aatgcccttg gcataaggca gcatggtgtg gcagttaaga 2550

 gatgggctgt gcagcccatc ctgagctcca gtcctgagtt tgctacttac 2600

 ttctgtggcc tctggaacct tatccaacct cttggtgctt cagtttcctc 2650

 atctgtgaaa ttagaattta taataattgc acctacctcc caggggtaac 2700

 taaatgaata aatataataa agtacttaca gtggttcctg acacagactc 2750

 agcactccgt cagtgttgcc atgactattt ttattatcat tattaatgat 2800

 tacttagatc aattatttag cagtggacta atggaagcta cagagcaggg 2850

 aagggaagca gatctaggga ggaaggcagt tttgatttga ggaggtttgc 2900

 acatgtagag aagcatactg gagaagcata tccagagggc gaaagatatc 2950

 tctccattgt gcatctgcct cttttgacgt tggaagacac atgtcttact 3000

 ccccaaaggg agcccagcac tgggagcctt cttgatgatc tcaaaaataa 3050

 tagctattca agaaaatcac caagtgactg tgaaaccgtc agttcggaag 3100

 gctggttaga acatgtggga gcaacatgaa tgttctacaa aagtttaaag 3150

 cagagattgt ttcaaatggg tgtagtagat attactgaaa accaaaaaag 3200

 agtgagattg tcagtgtaag aatgtgattt aatgtttgta gtgcttacaa 3250

 ttttgtgtac caactggatg actaaaaaga gtaaaataat ttaattaata 3300

 gctcatattt tatgtgtgaa aacatgttag tgaacatata taatcaaaat 3350

 agatttcatt gctattgcat agtctctaat acatagaatg attttgcttt 3400

 tctcttttat tatacttgct ttaaaatact tgaaatatat tttgcattaa 3450

 atgcatttca agttaaatgt cttaaatgta tacattagat gtgtgtttta 3500

 aaatgcataa aacacgttga aa 3522

<210> 5580
<211> 541
<212> PRT
<213> Homo sapien

<400> 5580
 Met Asn Cys Arg Glu Leu Pro Leu Thr Leu Trp Val Leu Ile Ser
   1               5                  10                  15

 Val Ser Thr Ala Glu Ser Cys Thr Ser Arg Pro His Ile Thr Val
                  20                  25                  30

 Val Glu Gly Glu Pro Phe Tyr Leu Lys His Cys Ser Cys Ser Leu
                  35                  40                  45

 Ala His Glu Ile Glu Thr Thr Thr Lys Ser Trp Tyr Lys Ser Ser
                  50                  55                  60

 Gly Ser Gln Glu His Val Glu Leu Asn Pro Arg Ser Ser Ser Arg
                  65                  70                  75

 Ile Ala Leu His Asp Cys Val Leu Glu Phe Trp Pro Val Glu Leu
                  80                  85                  90

 Asn Asp Thr Gly Ser Tyr Phe Phe Gln Met Lys Asn Tyr Thr Gln
                  95                 100                 105

 Lys Trp Lys Leu Asn Val Ile Arg Arg Asn Lys His Ser Cys Phe
                 110                 115                 120

 Thr Glu Arg Gln Val Thr Ser Lys Ile Val Glu Val Lys Lys Phe
                 125                 130                 135

 Phe Gln Ile Thr Cys Glu Asn Ser Tyr Tyr Gln Thr Leu Val Asn
                 140                 145                 150

 Ser Thr Ser Leu Tyr Lys Asn Cys Lys Lys Leu Leu Leu Glu Asn
                 155                 160                 165

 Asn Lys Asn Pro Thr Ile Lys Lys Asn Ala Glu Phe Glu Asp Gln
                 170                 175                 180

 Gly Tyr Tyr Ser Cys Val His Phe Leu His His Asn Gly Lys Leu
                 185                 190                 195

 Phe Asn Ile Thr Lys Thr Phe Asn Ile Thr Ile Val Glu Asp Arg
                 200                 205                 210

 Ser Asn Ile Val Pro Val Leu Leu Gly Pro Lys Leu Asn His Val
                 215                 220                 225

 Ala Val Glu Leu Gly Lys Asn Val Arg Leu Asn Cys Ser Ala Leu
                 230                 235                 240

 Leu Asn Glu Glu Asp Val Ile Tyr Trp Met Phe Gly Glu Glu Asn
                 245                 250                 255

 Gly Ser Asp Pro Asn Ile His Glu Glu Lys Glu Met Arg Ile Met
                 260                 265                 270

 Thr Pro Glu Gly Lys Trp His Ala Ser Lys Val Leu Arg Ile Glu
                 275                 280                 285

 Asn Ile Gly Glu Ser Asn Leu Asn Val Leu Tyr Asn Cys Thr Val
                 290                 295                 300

 Ala Ser Thr Gly Gly Thr Asp Thr Lys Ser Phe Ile Leu Val Arg
                 305                 310                 315

 Lys Ala Asp Met Ala Asp Ile Pro Gly His Val Phe Thr Arg Gly
                 320                 325                 330

 Met Ile Ile Ala Val Leu Ile Leu Val Ala Val Val Cys Leu Val
                 335                 340                 345

 Thr Val Cys Val Ile Tyr Arg Val Asp Leu Val Leu Phe Tyr Arg
                 350                 355                 360

 His Leu Thr Arg Arg Asp Glu Thr Leu Thr Asp Gly Lys Thr Tyr
                 365                 370                 375

 Asp Ala Phe Val Ser Tyr Leu Lys Glu Cys Arg Pro Glu Asn Gly
                 380                 385                 390

 Glu Glu His Thr Phe Ala Val Glu Ile Leu Pro Arg Val Leu Glu
                 395                 400                 405

 Lys His Phe Gly Tyr Lys Leu Cys Ile Phe Glu Arg Asp Val Val
                 410                 415                 420

 Pro Gly Gly Ala Val Val Asp Glu Ile His Ser Leu Ile Glu Lys
                 425                 430                 435

 Ser Arg Arg Leu Ile Ile Val Leu Ser Lys Ser Tyr Met Ser Asn
                 440                 445                 450

 Glu Val Arg Tyr Glu Leu Glu Ser Gly Leu His Glu Ala Leu Val
                 455                 460                 465

 Glu Arg Lys Ile Lys Ile Ile Leu Ile Glu Phe Thr Pro Val Thr
                 470                 475                 480

 Asp Phe Thr Phe Leu Pro Gln Ser Leu Lys Leu Leu Lys Ser His
                 485                 490                 495

 Arg Val Leu Lys Trp Lys Ala Asp Lys Ser Leu Ser Tyr Asn Ser
                 500                 505                 510

 Arg Phe Trp Lys Asn Leu Leu Tyr Leu Met Pro Ala Lys Thr Val
                 515                 520                 525

 Lys Pro Gly Arg Asp Glu Pro Glu Val Leu Pro Val Leu Ser Glu
                 530                 535                 540

 Ser


<210> 5581
<211> 2210
<212> DNA
<213> Homo sapien

<400> 5581
 agccgcggcc tcaactaaaa gtggccattg acctttcaag ctttcgagca 50

 gtgatgcaat agaatagtat ttcaaagaaa aatgcttatc gaaattttgg 100

 atccggtttt cccgtgattg ttaagggttt cttttaaaaa gtaggtcaca 150

 tttcaagtag gtcatatttc gggggcgggt gcgcagacaa ggagatgagt 200

 ttccactaag gccagggggc ctccaacggg gttggaggtg agaatcccag 250

 gtagggtaga ggtgccgaga tccttccgaa tcccagccct ggggcgtcag 300

 ccctgcaggg aatggcagag acactctccg gactgaggga accgaggcca 350

 gtcaccaagc cccttccggg cgcgcaggcg atcagtgggt gaccgcggct 400

 gcgagggact ttgtcatccg tcctccagga tctggggaga aagagcccca 450

 tcccttctct ctctgccacc atttcggaca ccccgcaggg actcgttttg 500

 ggattcgcac tgacttcaag gaaggacgcg aacccttctc tgaccccagc 550

 tcgggcggcc acctgtcttt gccgcggtga cccttctctc atgaccctgc 600

 ggtgccttga gccctccggg aatggcgggg aagggacgcg gagccagtgg 650

 gggaccgcgg ggtcggcgga ggagccatcc ccgcaggcgg cgcgtctggc 700

 gaaggccctg cgggagctcg gtcagacagg atggtactgg ggaagtatga 750

 ctgttaatga agccaaagag aaattaaaag aggcaccaga aggaactttc 800

 ttgattagag atagctcgca ttcagactac ctactaacaa tatctgttaa 850

 aacatcagct ggaccaacta atcttcgaat cgaataccaa gacggaaaat 900

 tcagattgga ctctatcata tgtgtcaaat ccaagcttaa acaatttgac 950

 agtgtggttc atctgatcga ctactatgtt cagatgtgca aggataagcg 1000

 gacaggtcca gaagcccccc ggaacggcac tgttcacctt tatctgacca 1050

 aaccgctcta cacgtcagca ccatctctgc agcatctctg taggctcacc 1100

 attaacaaat gtaccggtgc catctgggga ctgcctttac caacaagact 1150

 aaaagattac ttggaagaat ataaattcca ggtataaatg tttctctttt 1200

 tttaaacatg tctcacatag agtatctccg aatgcagcta tgtaaaagag 1250

 aaccaaaact tgagtgctct ggataactat atggaatgct ttctaagaac 1300

 agctgaagct aatctaattt aaatttaaca gcttgaagag gtagctaggt 1350

 gtttaaagtt cctccagata cttttacctg agtgatgctt cccttcctaa 1400

 ggctgaccaa gacctgttga tccttttaga ttaaaaataa aatgtcgcat 1450

 gtaaaggctg aagtcgcgtt ttatcagaat gccttgcctt cttaggttct 1500

 tttccattat gtcaaaggtc caggctccag taggagagaa agaactcctc 1550

 ataggaatac tgaagaagtg ggaaggaacc aagctgacac aggcctcact 1600

 gcaatttgat atgcctgctg atcagagtct cttgggcatt ttatattttg 1650

 cattctgatg tacctaggag ttttgttaaa cagatgatgt atgtgagtat 1700

 ttatcccatt ttatgcaatt aaccaaatca accaaaaaaa gtgaccatga 1750

 agtcctgtat ttgtcttttt actacatgta ggaactctca tgtgaatgag 1800

 tactgtagta atccattcta tgggagcctt atttcagaaa tatttcaaac 1850

 tggtgcaaat ggaaaagact ttctcttttc ctttaaagct aaagacaaga 1900

 atatcatgct atacaggtgc aactcaatcc ccgttaataa aaaccaatgt 1950

 aggtataggc attctaccct ttgaaatagc tgtgtcccaa cctgttgcca 2000

 ttgatttttt ggaaatggct ttagaaatat ccaagttgtc cttgaattgt 2050

 ctaaccatgg acataaacag ttgtctccct tctactgtgt agaatacttt 2100

 gacttaattt tcttccagat acagggggat acctgcctgt ttttcaaagt 2150

 gtttatttac tgctgttact atttgattag aatgtattaa ataaaaaaaa 2200

 cctgatttct 2210

<210> 5582
<211> 198
<212> PRT
<213> Homo sapien

<400> 5582
 Met Thr Leu Arg Cys Leu Glu Pro Ser Gly Asn Gly Gly Glu Gly
   1               5                  10                  15

 Thr Arg Ser Gln Trp Gly Thr Ala Gly Ser Ala Glu Glu Pro Ser
                  20                  25                  30

 Pro Gln Ala Ala Arg Leu Ala Lys Ala Leu Arg Glu Leu Gly Gln
                  35                  40                  45

 Thr Gly Trp Tyr Trp Gly Ser Met Thr Val Asn Glu Ala Lys Glu
                  50                  55                  60

 Lys Leu Lys Glu Ala Pro Glu Gly Thr Phe Leu Ile Arg Asp Ser
                  65                  70                  75

 Ser His Ser Asp Tyr Leu Leu Thr Ile Ser Val Lys Thr Ser Ala
                  80                  85                  90

 Gly Pro Thr Asn Leu Arg Ile Glu Tyr Gln Asp Gly Lys Phe Arg
                  95                 100                 105

 Leu Asp Ser Ile Ile Cys Val Lys Ser Lys Leu Lys Gln Phe Asp
                 110                 115                 120

 Ser Val Val His Leu Ile Asp Tyr Tyr Val Gln Met Cys Lys Asp
                 125                 130                 135

 Lys Arg Thr Gly Pro Glu Ala Pro Arg Asn Gly Thr Val His Leu
                 140                 145                 150

 Tyr Leu Thr Lys Pro Leu Tyr Thr Ser Ala Pro Ser Leu Gln His
                 155                 160                 165

 Leu Cys Arg Leu Thr Ile Asn Lys Cys Thr Gly Ala Ile Trp Gly
                 170                 175                 180

 Leu Pro Leu Pro Thr Arg Leu Lys Asp Tyr Leu Glu Glu Tyr Lys
                 185                 190                 195

 Phe Gln Val


<210> 5583
<211> 1236
<212> DNA
<213> Homo sapien

<400> 5583
 acttggcctt acactccgct cggctcacca tgtgtcactc tcgcagctgc 50

 cacccgacca tgaccatcct gcaggccccg accccggccc cctccaccat 100

 cccgggaccc cggcggggct ccggtcctga gatcttcacc ttcgaccctc 150

 tcccggagcc cgcagcggcc cctgccgggc gccccagcgc ctctcgcggg 200

 caccgaaagc gcagccgcag ggttctctac cctcgagtgg tccggcgcca 250

 gctgccagtc gaggaaccga acccagccaa aaggcttctc tttctgctgc 300

 tcaccatcgt cttctgccag atcctgatgg ctgaagaggg tgtgccggcg 350

 cccctgcctc cagaggacgc ccctaacgcc gcatccctgg cgcccacccc 400

 tgtgtccccc gtcctcgagc cctttaatct gacttcggag ccctcggact 450

 acgctctgga cctcagcact ttcctccagc aacacccggc cgccttctaa 500

 ctgtgactcc ccgcactccc caaaaagaat ccgaaaaacc acaaagaaac 550

 accaggcgta cctggtgcgc gagagcgtat ccccaactgg gacttccgag 600

 gcaacttgaa ctcagaacac tacagcggag acgccacccg gtgcttgagg 650

 cgggaccgag gcgcacagag accgaggcgc atagagaccg aggcacagcc 700

 cagctggggc taggcccggt gggaaggaga gcgtcgttaa tttatttctt 750

 attgctccta attaatattt atatgtattt atgtacgtcc tcctaggtga 800

 tggagatgtg tacgtaatat ttattttaac ttatgcaagg gtgtgagatg 850

 ttccccctgc tgtaaatgca ggtctcttgg tatttattga gctttgtggg 900

 actggtggaa gcaggacacc tggaactgcg gcaaagtagg agaagaaatg 950

 gggaggactc gggtggggga ggacgtcccg gctgggatga agtctggtgg 1000

 tgggtcgtaa gtttaggagg tgactgcatc ctccagcatc tcaactccgt 1050

 ctgtctactg tgtgagactt cggcggacca ttaggaatga gatccgtgag 1100

 atccttccat cttcttgaag tcgcctttag ggtggctacg aggtagaggg 1150

 gtgggggttg gtgggctgtc acggagcgac tgtcgagatc gcctagtatg 1200

 ttctgtgaac acaaataaaa ttgatttact gtctgc 1236

<210> 5584
<211> 156
<212> PRT
<213> Homo sapien

<400> 5584
 Met Cys His Ser Arg Ser Cys His Pro Thr Met Thr Ile Leu Gln
   1               5                  10                  15

 Ala Pro Thr Pro Ala Pro Ser Thr Ile Pro Gly Pro Arg Arg Gly
                  20                  25                  30

 Ser Gly Pro Glu Ile Phe Thr Phe Asp Pro Leu Pro Glu Pro Ala
                  35                  40                  45

 Ala Ala Pro Ala Gly Arg Pro Ser Ala Ser Arg Gly His Arg Lys
                  50                  55                  60

 Arg Ser Arg Arg Val Leu Tyr Pro Arg Val Val Arg Arg Gln Leu
                  65                  70                  75

 Pro Val Glu Glu Pro Asn Pro Ala Lys Arg Leu Leu Phe Leu Leu
                  80                  85                  90

 Leu Thr Ile Val Phe Cys Gln Ile Leu Met Ala Glu Glu Gly Val
                  95                 100                 105

 Pro Ala Pro Leu Pro Pro Glu Asp Ala Pro Asn Ala Ala Ser Leu
                 110                 115                 120

 Ala Pro Thr Pro Val Ser Pro Val Leu Glu Pro Phe Asn Leu Thr
                 125                 130                 135

 Ser Glu Pro Ser Asp Tyr Ala Leu Asp Leu Ser Thr Phe Leu Gln
                 140                 145                 150

 Gln His Pro Ala Ala Phe
                 155

<210> 5585
<211> 591
<212> DNA
<213> Homo sapien

<400> 5585
 atggcggcca tccgcaagaa gctggtggtg gtgggcgacg gcgcgtgtgg 50

 caagacgtgc ctgctgatcg tgttcagtaa ggacgagttc cccgaggtgt 100

 acgtgcccac cgtcttcgag aactatgtgg ccgacattga ggtggacggc 150

 aagcaggtgg agctggcgct gtgggacacg gcgggccagg aggactacga 200

 ccgcctgcgg ccgctctcct acccggacac cgacgtcatt ctcatgtgct 250

 tctcggtgga cagcccggac tcgctggaga acatccccga gaagtgggtc 300

 cccgaggtga agcacttctg tcccaatgtg cccatcatcc tggtggccaa 350

 caaaaaagac ctgcgcagcg acgagcatgt ccgcacagag ctggcccgca 400

 tgaagcagga acccgtgcgc acggatgacg gccgcgccat ggccgtgcgc 450

 atccaagcct acgactacct cgagtgctct gccaagacca aggaaggcgt 500

 gcgcgaggtc ttcgagacgg ccacgcgcgc cgcgctgcag aagcgctacg 550

 gctcccagaa cggctgcatc aactgctgca aggtgctatg a 591

<210> 5586
<211> 196
<212> PRT
<213> Homo sapien

<400> 5586
 Met Ala Ala Ile Arg Lys Lys Leu Val Val Val Gly Asp Gly Ala
   1               5                  10                  15

 Cys Gly Lys Thr Cys Leu Leu Ile Val Phe Ser Lys Asp Glu Phe
                  20                  25                  30

 Pro Glu Val Tyr Val Pro Thr Val Phe Glu Asn Tyr Val Ala Asp
                  35                  40                  45

 Ile Glu Val Asp Gly Lys Gln Val Glu Leu Ala Leu Trp Asp Thr
                  50                  55                  60

 Ala Gly Gln Glu Asp Tyr Asp Arg Leu Arg Pro Leu Ser Tyr Pro
                  65                  70                  75

 Asp Thr Asp Val Ile Leu Met Cys Phe Ser Val Asp Ser Pro Asp
                  80                  85                  90

 Ser Leu Glu Asn Ile Pro Glu Lys Trp Val Pro Glu Val Lys His
                  95                 100                 105

 Phe Cys Pro Asn Val Pro Ile Ile Leu Val Ala Asn Lys Lys Asp
                 110                 115                 120

 Leu Arg Ser Asp Glu His Val Arg Thr Glu Leu Ala Arg Met Lys
                 125                 130                 135

 Gln Glu Pro Val Arg Thr Asp Asp Gly Arg Ala Met Ala Val Arg
                 140                 145                 150

 Ile Gln Ala Tyr Asp Tyr Leu Glu Cys Ser Ala Lys Thr Lys Glu
                 155                 160                 165

 Gly Val Arg Glu Val Phe Glu Thr Ala Thr Arg Ala Ala Leu Gln
                 170                 175                 180

 Lys Arg Tyr Gly Ser Gln Asn Gly Cys Ile Asn Cys Cys Lys Val
                 185                 190                 195

 Leu


<210> 5587
<211> 885
<212> DNA
<213> Homo sapien

<400> 5587
 agcctacgca cgaaagtgac tagggaggaa ggatattata aagtgatgca 50

 aacagaaatt ccaccagcct ccatgtatca tcatgtgtca taactcagtc 100

 aagctcagtg agcattctca gcacattgcc tcaacagctt caaggtgagc 150

 cagctcaaga ctttgctctc caccaggcag aagatgacag actgtgaatt 200

 tggatatatt tacaggctgg ctcaggacta tctgcagtgc gtcctacaga 250

 taccacaacc tggatcaggt ccaagcaaaa cgtccagagt gctacaaaat 300

 gttgcgttct cagtccaaaa agaagtggaa aagaatctga agtcatgctt 350

 ggacaatgtt aatgttgtgt ccgtagacac tgccagaaca ctattcaacc 400

 aagtgatgga aaaggagttt gaagacggca tcattaactg gggaagaatt 450

 gtaaccatat ttgcatttga aggtattctc atcaagaaac ttctacgaca 500

 gcaaattgcc ccggatgtgg atacctataa ggagatttca tattttgttg 550

 cggagttcat aatgaataac acaggagaat ggataaggca aaacggaggc 600

 tgggaaaatg gctttgtaaa gaagtttgaa cctaaatctg gctggatgac 650

 ttttctagaa gttacaggaa agatctgtga aatgctatct ctcctgaagc 700

 aatactgttg accagaaagg acactccata ttgtgaaacc ggcctaattt 750

 ttctgactga tatggaaacg attgccaaca catacttcta cttttaaata 800

 aacaactttg atgatgtaac ttgaccttcc agagttatgg aaattttgtc 850

 cccatgtaat gaataaattg tatgtatttt tctct 885

<210> 5588
<211> 175
<212> PRT
<213> Homo sapien

<400> 5588
 Met Thr Asp Cys Glu Phe Gly Tyr Ile Tyr Arg Leu Ala Gln Asp
   1               5                  10                  15

 Tyr Leu Gln Cys Val Leu Gln Ile Pro Gln Pro Gly Ser Gly Pro
                  20                  25                  30

 Ser Lys Thr Ser Arg Val Leu Gln Asn Val Ala Phe Ser Val Gln
                  35                  40                  45

 Lys Glu Val Glu Lys Asn Leu Lys Ser Cys Leu Asp Asn Val Asn
                  50                  55                  60

 Val Val Ser Val Asp Thr Ala Arg Thr Leu Phe Asn Gln Val Met
                  65                  70                  75

 Glu Lys Glu Phe Glu Asp Gly Ile Ile Asn Trp Gly Arg Ile Val
                  80                  85                  90

 Thr Ile Phe Ala Phe Glu Gly Ile Leu Ile Lys Lys Leu Leu Arg
                  95                 100                 105

 Gln Gln Ile Ala Pro Asp Val Asp Thr Tyr Lys Glu Ile Ser Tyr
                 110                 115                 120

 Phe Val Ala Glu Phe Ile Met Asn Asn Thr Gly Glu Trp Ile Arg
                 125                 130                 135

 Gln Asn Gly Gly Trp Glu Asn Gly Phe Val Lys Lys Phe Glu Pro
                 140                 145                 150

 Lys Ser Gly Trp Met Thr Phe Leu Glu Val Thr Gly Lys Ile Cys
                 155                 160                 165

 Glu Met Leu Ser Leu Leu Lys Gln Tyr Cys
                 170                 175

<210> 5589
<211> 1255
<212> DNA
<213> Homo sapien

<400> 5589
 ctaaagatga aacggctggt ttgtgtgctc ttggtgtgct cctctgcagt 50

 ggcacagttg cataaagatc ctaccctgga tcaccactgg catctctgga 100

 agaaaaccta tggcaaacaa tacaaggaaa agaatgaaga agcagtacga 150

 cgtctcatct gggaaaagaa tctaaagttt gtgatgcttc acaacctgga 200

 gcattcaatg ggaatgcact catacgatct gggcatgaac cacctgggag 250

 acatgaccag tgaagaagtg atgtctttga cgagttccct gagagttccc 300

 agccagtggc agagaaatat cacatataag tcaaacccta atcggatatt 350

 gcctgattct gtggactgga gagagaaagg gtgtgttact gaagtgaaat 400

 atcaaggttc ttgtggtgct tgctgggctt tcagtgctgt gggggccctg 450

 gaagcacagc tgaagctgaa aacaggaaag ctggtgactc tcagtgccca 500

 gaacctggtg gattgctcaa ctgaaaaata tggaaacaaa ggctgcaatg 550

 gtggcttcat gacaacggct ttccagtaca tcattgataa caagggcatc 600

 gactcagacg cttcctatcc ctacaaagcc atggatcaga aatgtcaata 650

 tgactcaaaa tatcgtgctg ccacatgttc aaagtacact gaacttcctt 700

 atgggagaga agatgtcctg aaagaagctg tggccaataa aggcccagtg 750

 tctgttggtg tagatgcgcg tcatccttct ttcttcctct acagaagtgg 800

 tgtctactat gaaccatcct gtactcagaa tgtgaatcat ggtgtacttg 850

 tggttggcta tggtgatctt aatgggaaag aatactggct tgtgaaaaac 900

 agctggggcc acaactttgg tgaagaagga tatattcgga tggcaagaaa 950

 taaaggaaat cattgtggga ttgctagctt tccctcttac ccagaaatct 1000

 agaggatctc tcctttttat aacaaatcaa gaaatatgaa gcactttctc 1050

 ttaacttaat ttttcctgct gtatccagaa gaaataattg tgtcatgatt 1100

 aatgtgtatt tactgtacta atagaaaata tagtttgagg ccgggcactg 1150

 tctggctcac gcctgtaatc ccagtacttg ggaggccaag gaggcatatc 1200

 aacttgaggc caggagttaa agagcagcct ggctaactgt gaaaccctct 1250

 ctact 1255

<210> 5590
<211> 331
<212> PRT
<213> Homo sapien

<400> 5590
 Met Lys Arg Leu Val Cys Val Leu Leu Val Cys Ser Ser Ala Val
   1               5                  10                  15

 Ala Gln Leu His Lys Asp Pro Thr Leu Asp His His Trp His Leu
                  20                  25                  30

 Trp Lys Lys Thr Tyr Gly Lys Gln Tyr Lys Glu Lys Asn Glu Glu
                  35                  40                  45

 Ala Val Arg Arg Leu Ile Trp Glu Lys Asn Leu Lys Phe Val Met
                  50                  55                  60

 Leu His Asn Leu Glu His Ser Met Gly Met His Ser Tyr Asp Leu
                  65                  70                  75

 Gly Met Asn His Leu Gly Asp Met Thr Ser Glu Glu Val Met Ser
                  80                  85                  90

 Leu Thr Ser Ser Leu Arg Val Pro Ser Gln Trp Gln Arg Asn Ile
                  95                 100                 105

 Thr Tyr Lys Ser Asn Pro Asn Arg Ile Leu Pro Asp Ser Val Asp
                 110                 115                 120

 Trp Arg Glu Lys Gly Cys Val Thr Glu Val Lys Tyr Gln Gly Ser
                 125                 130                 135

 Cys Gly Ala Cys Trp Ala Phe Ser Ala Val Gly Ala Leu Glu Ala
                 140                 145                 150

 Gln Leu Lys Leu Lys Thr Gly Lys Leu Val Thr Leu Ser Ala Gln
                 155                 160                 165

 Asn Leu Val Asp Cys Ser Thr Glu Lys Tyr Gly Asn Lys Gly Cys
                 170                 175                 180

 Asn Gly Gly Phe Met Thr Thr Ala Phe Gln Tyr Ile Ile Asp Asn
                 185                 190                 195

 Lys Gly Ile Asp Ser Asp Ala Ser Tyr Pro Tyr Lys Ala Met Asp
                 200                 205                 210

 Gln Lys Cys Gln Tyr Asp Ser Lys Tyr Arg Ala Ala Thr Cys Ser
                 215                 220                 225

 Lys Tyr Thr Glu Leu Pro Tyr Gly Arg Glu Asp Val Leu Lys Glu
                 230                 235                 240

 Ala Val Ala Asn Lys Gly Pro Val Ser Val Gly Val Asp Ala Arg
                 245                 250                 255

 His Pro Ser Phe Phe Leu Tyr Arg Ser Gly Val Tyr Tyr Glu Pro
                 260                 265                 270

 Ser Cys Thr Gln Asn Val Asn His Gly Val Leu Val Val Gly Tyr
                 275                 280                 285

 Gly Asp Leu Asn Gly Lys Glu Tyr Trp Leu Val Lys Asn Ser Trp
                 290                 295                 300

 Gly His Asn Phe Gly Glu Glu Gly Tyr Ile Arg Met Ala Arg Asn
                 305                 310                 315

 Lys Gly Asn His Cys Gly Ile Ala Ser Phe Pro Ser Tyr Pro Glu
                 320                 325                 330

 Ile


<210> 5591
<211> 2997
<212> DNA
<213> Homo sapien

<400> 5591
 ggactgcggt ctcgggcagc aatggccgag aagcgcgaca cacgggactc 50

 cgaagcccag cggctccccg actccttcaa ggacagcccc agtaagggcc 100

 ttggaccttg cggatggatt ttggtggcgt tctcattctt attcaccgtt 150

 ataactttcc caatctcaat atggatgtgc ataaagatta taaaagagta 200

 tgaaagagcc atcatcttta gattgggtcg cattttacaa ggaggagcca 250

 aaggacctgg tttgtttttt attctgccat gcactgacag cttcatcaaa 300

 gtggacatga gaactatttc atttgatatt cctcctcagg agatcctgac 350

 aaaggattca gtgacaatta gcgtggatgg tgtggtctat taccgcgttc 400

 agaatgcaac cctggctgtg gcaaatatca ccaacgctga ctcagcaacc 450

 cgtcttttgg cacaaactac tctgaggaat gttctgggca ccaagaatct 500

 ttctcagatc ctctctgaca gagaagaaat tgcacacaac atgcagtcta 550

 ctctggatga tgccactgat gcctggggaa taaaggtgga gcgtgtggaa 600

 attaaggatg tgaaactacc tgtgcagctc cagagagcta tggctgcaga 650

 agcagaagcg tcccgcgagg cccgcgccaa ggttattgca gccgaaggag 700

 aaatgaatgc atccagggct ctgaaagaag cctccatggt catcactgaa 750

 tctcctgcag cccttcagct ccgatacctg cagacactga ccaccattgc 800

 tgctgagaaa aactcaacaa ttgtcttccc tctgcccata gatatgctgc 850

 aaggaatcat aggggcaaaa cacagccatc taggctagtg tagagatgag 900

 cgctagcctt ccaagcatga agtcggggac caaattagcc tttaactcat 950

 aaagagaggg tagggctttt ctttttccat atgtcaattg tggtgttccc 1000

 agaatgtata gcagttataa aaataggtga aagaattgtt agcttgtaaa 1050

 tactgagaga ttggtgattt atataaggta atctgttagt cttaaaatag 1100

 ttaaaagttt gtatttttag attattatgt agtaggttag atccctcttg 1150

 ttttgacttc cactgactca ttctgaaccc cctaagcacc caggccacag 1200

 gcaagaacct gggctgtaac tgccacctga caccgctgac tggctaaatg 1250

 ctttgcagaa agtgatgacc ttacaccaca accagcttct ccaggtcata 1300

 tgtgccttac ctccagaagt cttttttttt ttttttttct gagatggagt 1350

 ttcactcttg ttgcccaggc tggagtgcaa tagcatgatc tcggctcact 1400

 gcaacctccg cctcctgggt tcaagagatt ctcctgcctc agcctcccca 1450

 gtagctggga ttacaggctc atgccaccat gcccagctaa tttttgtatt 1500

 attattattg ttttttagta gagacggggt ttcaccatgt tggccaggct 1550

 agtcacgaac tcctaacctc aggtgatcca cccacctctg cctccaaagt 1600

 gctggattac aggctgagct accaccctgg tttggagagt cttaattaat 1650

 tgaaatttcc ctaatgttca tttattttct aaatccagcc gtgtttcaga 1700

 ataatcctta cttgagagta gccattttct tgtgtacttg tcagaactag 1750

 aggaaatagc caagactaat gaaaaacatt actctaaccc ttaaaagact 1800

 tttaaattca ctactagagt ggtcatttta aaaatacatc catgttttaa 1850

 cttattttga gcctttcttt tatgagtaaa tgattcctcc ttgttctgtc 1900

 tttcaaacca gctaaatatt tgtcacaaaa gtgacttttt tctcactgtt 1950

 gcctattttc atatatcagg ttttaaatag ttttaatttt ttaataaaat 2000

 ttttctctac gttctatatg caattgttat atatctattt gaatagctga 2050

 aggactaaaa tactttttta agagataact tcaggaaacc attatatttt 2100

 actatctgca tgctgttaac tgtggtacac tgtgaaatat gttgattaca 2150

 aacccattca ttacatagta taaggaattc acagtatatt gactatatag 2200

 tgtctaatga ctgggcagat actgtcaact tacaatatct atatagagag 2250

 gctttaaact taccttactc attctctatg atgtatgact tgatgctgaa 2300

 agaggaagct ggtcagctcc tcatggacaa caaattctta gtctataata 2350

 ttaggagaca tctctagttt tgcaaatgtc tgtgaatctg agcaacctgg 2400

 acttctgctt actggccaga aagctggcgg gtgacatttg taacatttcc 2450

 tctttgagac tctgagttca cctagagaag tctaagcata acagctttct 2500

 ttcccagcac gagcctttat agctctcttt agctcaacca ctctgtccat 2550

 ccagccaatg gatgtccttc cctgtaccca attcaagctt attttaggga 2600

 agccttgaaa ctaccatgta tctggctcta gctgagttat tgaggattga 2650

 gccagtgcaa cgttaaactc agtgcactta catttgattt aaatgatggt 2700

 tttatctgtt gtgtgaagtg gttcaccctt gaggaccagg agcctccata 2750

 tcctgactga aaaccttttc tgagacttag agtaacagta cttttggttc 2800

 cttgagttct cctgtctcca gatacctaaa tgaccttgac ttttctgcct 2850

 tgtgaattcg tagtccaatc agctgaaatt aaatcacttg ggagggacgc 2900

 atagaaggag ctctaggaac acagtgccag tgcagaagtt tctccaggtg 2950

 gcctcccttt ccaacaatgt acataataaa gtgtatgcac tttcact 2997

<210> 5592
<211> 288
<212> PRT
<213> Homo sapien

<400> 5592
 Met Ala Glu Lys Arg Asp Thr Arg Asp Ser Glu Ala Gln Arg Leu
   1               5                  10                  15

 Pro Asp Ser Phe Lys Asp Ser Pro Ser Lys Gly Leu Gly Pro Cys
                  20                  25                  30

 Gly Trp Ile Leu Val Ala Phe Ser Phe Leu Phe Thr Val Ile Thr
                  35                  40                  45

 Phe Pro Ile Ser Ile Trp Met Cys Ile Lys Ile Ile Lys Glu Tyr
                  50                  55                  60

 Glu Arg Ala Ile Ile Phe Arg Leu Gly Arg Ile Leu Gln Gly Gly
                  65                  70                  75

 Ala Lys Gly Pro Gly Leu Phe Phe Ile Leu Pro Cys Thr Asp Ser
                  80                  85                  90

 Phe Ile Lys Val Asp Met Arg Thr Ile Ser Phe Asp Ile Pro Pro
                  95                 100                 105

 Gln Glu Ile Leu Thr Lys Asp Ser Val Thr Ile Ser Val Asp Gly
                 110                 115                 120

 Val Val Tyr Tyr Arg Val Gln Asn Ala Thr Leu Ala Val Ala Asn
                 125                 130                 135

 Ile Thr Asn Ala Asp Ser Ala Thr Arg Leu Leu Ala Gln Thr Thr
                 140                 145                 150

 Leu Arg Asn Val Leu Gly Thr Lys Asn Leu Ser Gln Ile Leu Ser
                 155                 160                 165

 Asp Arg Glu Glu Ile Ala His Asn Met Gln Ser Thr Leu Asp Asp
                 170                 175                 180

 Ala Thr Asp Ala Trp Gly Ile Lys Val Glu Arg Val Glu Ile Lys
                 185                 190                 195

 Asp Val Lys Leu Pro Val Gln Leu Gln Arg Ala Met Ala Ala Glu
                 200                 205                 210

 Ala Glu Ala Ser Arg Glu Ala Arg Ala Lys Val Ile Ala Ala Glu
                 215                 220                 225

 Gly Glu Met Asn Ala Ser Arg Ala Leu Lys Glu Ala Ser Met Val
                 230                 235                 240

 Ile Thr Glu Ser Pro Ala Ala Leu Gln Leu Arg Tyr Leu Gln Thr
                 245                 250                 255

 Leu Thr Thr Ile Ala Ala Glu Lys Asn Ser Thr Ile Val Phe Pro
                 260                 265                 270

 Leu Pro Ile Asp Met Leu Gln Gly Ile Ile Gly Ala Lys His Ser
                 275                 280                 285

 His Leu Gly


<210> 5593
<211> 960
<212> DNA
<213> Homo sapien

<400> 5593
 agcagctcca accagggcag ccttcctgag aagatgcaac caatcctgct 50

 tctgctggcc ttcctcctgc tgcccagggc agatgcaggg gagatcatcg 100

 ggggacatga ggccaagccc cactcccgcc cctacatggc ttatcttatg 150

 atctgggatc agaagtctct gaagaggtgc ggtggcttcc tgatacaaga 200

 cgacttcgtg ctgacagctg ctcactgttg gggaagctcc ataaatgtca 250

 ccttgggggc ccacaatatc aaagaacagg agccgaccca gcagtttatc 300

 cctgtgaaaa gacccatccc ccatccagcc tataatccta agaacttctc 350

 caacgacatc atgctactgc agctggagag aaaggccaag cggaccagag 400

 ctgtgcagcc cctcaggcta cctagcaaca aggcccaggt gaagccaggg 450

 cagacatgca gtgtggccgg ctgggggcag acggcccccc tgggaaaaca 500

 ctcacacaca ctacaagagg tgaagatgac agtgcaggaa gatcgaaagt 550

 gcgaatctga cttacgccat tattacgaca gtaccattga gttgtgcgtg 600

 ggggacccag agattaaaaa gacttccttt aagggggact ctggaggccc 650

 tcttgtgtgt aacaaggtgg cccagggcat tgtctcctat ggacgaaaca 700

 atggcatgcc tccacgagcc tgcaccaaag tctcaagctt tgtacactgg 750

 ataaagaaaa ccatgaaacg ctactaacta caggaagcaa actaagcccc 800

 cgctgtaatg aaacaccttc tctggagcca agtccagatt tacactggga 850

 gaggtgccag caactgaata aatacctctc ccagtgtaaa tctggagcca 900

 agtccagatt tacactggga gaggtgccag caactgaata aatacctctt 950

 agctgagtgg 960

<210> 5594
<211> 247
<212> PRT
<213> Homo sapien

<400> 5594
 Met Gln Pro Ile Leu Leu Leu Leu Ala Phe Leu Leu Leu Pro Arg
   1               5                  10                  15

 Ala Asp Ala Gly Glu Ile Ile Gly Gly His Glu Ala Lys Pro His
                  20                  25                  30

 Ser Arg Pro Tyr Met Ala Tyr Leu Met Ile Trp Asp Gln Lys Ser
                  35                  40                  45

 Leu Lys Arg Cys Gly Gly Phe Leu Ile Gln Asp Asp Phe Val Leu
                  50                  55                  60

 Thr Ala Ala His Cys Trp Gly Ser Ser Ile Asn Val Thr Leu Gly
                  65                  70                  75

 Ala His Asn Ile Lys Glu Gln Glu Pro Thr Gln Gln Phe Ile Pro
                  80                  85                  90

 Val Lys Arg Pro Ile Pro His Pro Ala Tyr Asn Pro Lys Asn Phe
                  95                 100                 105

 Ser Asn Asp Ile Met Leu Leu Gln Leu Glu Arg Lys Ala Lys Arg
                 110                 115                 120

 Thr Arg Ala Val Gln Pro Leu Arg Leu Pro Ser Asn Lys Ala Gln
                 125                 130                 135

 Val Lys Pro Gly Gln Thr Cys Ser Val Ala Gly Trp Gly Gln Thr
                 140                 145                 150

 Ala Pro Leu Gly Lys His Ser His Thr Leu Gln Glu Val Lys Met
                 155                 160                 165

 Thr Val Gln Glu Asp Arg Lys Cys Glu Ser Asp Leu Arg His Tyr
                 170                 175                 180

 Tyr Asp Ser Thr Ile Glu Leu Cys Val Gly Asp Pro Glu Ile Lys
                 185                 190                 195

 Lys Thr Ser Phe Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Asn
                 200                 205                 210

 Lys Val Ala Gln Gly Ile Val Ser Tyr Gly Arg Asn Asn Gly Met
                 215                 220                 225

 Pro Pro Arg Ala Cys Thr Lys Val Ser Ser Phe Val His Trp Ile
                 230                 235                 240

 Lys Lys Thr Met Lys Arg Tyr
                 245

<210> 5595
<211> 1221
<212> DNA
<213> Homo sapien

<400> 5595
 gcggcctggg cggccgcacc atggactcgg gaaccgagga gtacgagctc 50

 aacggcggcc tgcctccggg cacacccggc tccccggacg cctcgccggc 100

 ccgctggggc tggaggcacg ggcccatcaa cgtgaaccat tacgccagca 150

 agaagagcgc agccgagagc atgctggaca tcgcgctgct gatggccaac 200

 gcgtcccagc tgaaggccgt cgtggaacag ggccccagct tcgccttcta 250

 tgtgcccctg gtggtcctca tctccatctc ccttgtgctg cagatcggcg 300

 tgggggtgct gctcatcttc cttgtcaagt acgaccttaa caacccggac 350

 aagcacgcca agctggactt cctcaacaac ctggccacgg gcctggtgtt 400

 catcatcgtg gtagtcaaca tcttcatcac ggccttcggg gtccagaagc 450

 ccttgatgga catggcaccc cagcagtagg acacccagga ccctggatgc 500

 tgcctgccct gcaactcagc tgcccgaccc caggagtcgc catacctgtg 550

 aggtgtccac ctccctgcac atggcactac ccagactgcc agagcccagg 600

 ctggcctcat ctgcaccatg tccccggacc agcccttgct ctgactgcgg 650

 ccaagcacca cgcaggaggc cactcttgtc tctcascagc tgttcccagg 700

 aggcagctcc ctcctggcac atgggggctg gcacaatagc ccagagggtc 750

 agaactggac agctgcagag acctgtgccc agagaagggt ctcgacccac 800

 tcaaggacac acagcaggtc cgtggatggg ctggatgagt gaccagggcc 850

 agcctctgtc tcaggacatt ccagaaggac aaggagatgt ctctccctct 900

 cccaaagcac cagcgtccct gcctcccgtg ggccctgtcc gggttgcccc 950

 tggtgacccc agcctctgtc cacttcctaa cccagggacc ctgcacagcc 1000

 agaactgcct ttggccctac ggatggccac tggctctggt ctaaagtgcc 1050

 tgggcttggt ggccatcaag agggagccag tcaggcctgt gagggccgta 1100

 gaccttgtat ataccctgca ccagcagtga ccgggcagag cccaaccccc 1150

 tccacggggg tcccagcacc cacttttcta atcatgaatg aacaataaag 1200

 cccacgctct ttgtcaggca a 1221

<210> 5596
<211> 152
<212> PRT
<213> Homo sapien

<400> 5596
 Met Asp Ser Gly Thr Glu Glu Tyr Glu Leu Asn Gly Gly Leu Pro
   1               5                  10                  15

 Pro Gly Thr Pro Gly Ser Pro Asp Ala Ser Pro Ala Arg Trp Gly
                  20                  25                  30

 Trp Arg His Gly Pro Ile Asn Val Asn His Tyr Ala Ser Lys Lys
                  35                  40                  45

 Ser Ala Ala Glu Ser Met Leu Asp Ile Ala Leu Leu Met Ala Asn
                  50                  55                  60

 Ala Ser Gln Leu Lys Ala Val Val Glu Gln Gly Pro Ser Phe Ala
                  65                  70                  75

 Phe Tyr Val Pro Leu Val Val Leu Ile Ser Ile Ser Leu Val Leu
                  80                  85                  90

 Gln Ile Gly Val Gly Val Leu Leu Ile Phe Leu Val Lys Tyr Asp
                  95                 100                 105

 Leu Asn Asn Pro Asp Lys His Ala Lys Leu Asp Phe Leu Asn Asn
                 110                 115                 120

 Leu Ala Thr Gly Leu Val Phe Ile Ile Val Val Val Asn Ile Phe
                 125                 130                 135

 Ile Thr Ala Phe Gly Val Gln Lys Pro Leu Met Asp Met Ala Pro
                 140                 145                 150

 Gln Gln


<210> 5597
<211> 1214
<212> DNA
<213> Homo sapien

<400> 5597
 gtctacaccc cctcctcaca cgcacttcac ctgggtcggg attctcaggt 50

 catgaacggt cccagccacc tccgggcagg gcgggtgagg acggggacgg 100

 ggcgtgtcca actggctgtg ggctcttgaa acccgagcat ggcacagcac 150

 ggggcgatgg gcgcgtttcg ggccctgtgc ggcctggcgc tgctgtgcgc 200

 gctcagcctg ggtcagcgcc ccaccggggg tcccgggtgc ggccctgggc 250

 gcctcctgct tgggacggga acggacgcgc gctgctgccg ggttcacacg 300

 acgcgctgct gccgcgatta cccgggcgag gagtgctgtt ccgagtggga 350

 ctgcatgtgt gtccagcctg aattccactg cggagaccct tgctgcacga 400

 cctgccggca ccacccttgt cccccaggcc agggggtaca gtcccagggg 450

 aaattcagtt ttggcttcca gtgtatcgac tgtgcctcgg ggaccttctc 500

 cgggggccac gaaggccact gcaaaccttg gacagactgc acccagttcg 550

 ggtttctcac tgtgttccct gggaacaaga cccacaacgc tgtgtgcgtc 600

 ccagggtccc cgccggcaga gccgcttggg tggctgaccg tcgtcctcct 650

 ggccgtggcc gcctgcgtcc tcctcctgac ctcggcccag cttggactgc 700

 acatctggca gctgaggagt cagtgcatgt ggccccgaga gacccagctg 750

 ctgctggagg tgccgccgtc gaccgaagac gccagaagct gccagttccc 800

 cgaggaagag cggggcgagc gatcggcaga ggagaagggg cggctgggag 850

 acctgtgggt gtgagcctgg ccgtcctccg gggccaccga ccgcagccag 900

 cccctcccca ggagctcccc aggccgcagg ggctctgcgt tctgctctgg 950

 gccgggccct gctcccctgg cagcagaagt gggtgcagga aggtggcagt 1000

 gaccagcgcc ctggaccatg cagttcggcg gccgcggctg ggccctgcag 1050

 gagggagaga gagacacagt catggccccc ttcctccctt gctggccctg 1100

 atggggtggg gtcttaggac gggaggctgt gtccgtgggt gtgcagtgcc 1150

 cagcacggga cccggctgca ggggaccttc aataaacact tgtccagtga 1200

 aaaaaaaaaa aaaa 1214

<210> 5598
<211> 241
<212> PRT
<213> Homo sapien

<400> 5598
 Met Ala Gln His Gly Ala Met Gly Ala Phe Arg Ala Leu Cys Gly
   1               5                  10                  15

 Leu Ala Leu Leu Cys Ala Leu Ser Leu Gly Gln Arg Pro Thr Gly
                  20                  25                  30

 Gly Pro Gly Cys Gly Pro Gly Arg Leu Leu Leu Gly Thr Gly Thr
                  35                  40                  45

 Asp Ala Arg Cys Cys Arg Val His Thr Thr Arg Cys Cys Arg Asp
                  50                  55                  60

 Tyr Pro Gly Glu Glu Cys Cys Ser Glu Trp Asp Cys Met Cys Val
                  65                  70                  75

 Gln Pro Glu Phe His Cys Gly Asp Pro Cys Cys Thr Thr Cys Arg
                  80                  85                  90

 His His Pro Cys Pro Pro Gly Gln Gly Val Gln Ser Gln Gly Lys
                  95                 100                 105

 Phe Ser Phe Gly Phe Gln Cys Ile Asp Cys Ala Ser Gly Thr Phe
                 110                 115                 120

 Ser Gly Gly His Glu Gly His Cys Lys Pro Trp Thr Asp Cys Thr
                 125                 130                 135

 Gln Phe Gly Phe Leu Thr Val Phe Pro Gly Asn Lys Thr His Asn
                 140                 145                 150

 Ala Val Cys Val Pro Gly Ser Pro Pro Ala Glu Pro Leu Gly Trp
                 155                 160                 165

 Leu Thr Val Val Leu Leu Ala Val Ala Ala Cys Val Leu Leu Leu
                 170                 175                 180

 Thr Ser Ala Gln Leu Gly Leu His Ile Trp Gln Leu Arg Ser Gln
                 185                 190                 195

 Cys Met Trp Pro Arg Glu Thr Gln Leu Leu Leu Glu Val Pro Pro
                 200                 205                 210

 Ser Thr Glu Asp Ala Arg Ser Cys Gln Phe Pro Glu Glu Glu Arg
                 215                 220                 225

 Gly Glu Arg Ser Ala Glu Glu Lys Gly Arg Leu Gly Asp Leu Trp
                 230                 235                 240

 Val


<210> 5599
<211> 1982
<212> DNA
<213> Homo sapien

<400> 5599
 ggcgagaggc gggctgaggc ggcccagcgg cggcaggtga ggcggaacca 50

 accctcctgg ccatgggagg ggccgtggtg gacgagggcc ccacaggcgt 100

 caaggcccct gacggcggct ggggctgggc cgtgctcttc ggctgtttcg 150

 tcatcactgg cttctcctac gccttcccca aggccgtcag tgtcttcttc 200

 aaggagctca tacaggagtt tgggatcggc tacagcgaca cagcctggat 250

 ctcctccatc ctgctggcca tgctctacgg gacaggtccg ctctgcagtg 300

 tgtgcgtgaa ccgctttggc tgccggcccg tcatgcttgt ggggggtctc 350

 tttgcgtcgc tgggcatggt ggctgcgtcc ttttgccgga gcatcatcca 400

 ggtctacctc accactgggg tcatcacggg gttgggtttg gcactcaact 450

 tccagccctc gctcatcatg ctgaaccgct acttcagcaa gcggcgcccc 500

 atggccaacg ggctggcggc agcaggtagc cctgtcttcc tgtgtgccct 550

 gagcccgctg gggcagctgc tgcaggaccg ctacggctgg cggggcggct 600

 tcctcatcct gggcggcctg ctgctcaact gctgcgtgtg tgccgcactc 650

 atgaggcccc tggtggtcac ggcccagccg ggctcggggc cgccgcgacc 700

 ctcccggcgc ctgctagacc tgagcgtctt ccgggaccgc ggctttgtgc 750

 tttacgccgt ggccgcctcg gtcatggtgc tggggctctt cgtcccgccc 800

 gtgttcgtgg tgagctacgc caaggacctg ggcgtgcccg acaccaaggc 850

 cgccttcctg ctcaccatcc tgggcttcat tgacatcttc gcgcggccgg 900

 ccgcgggctt cgtggcgggg cttgggaagg tgcggcccta ctccgtctac 950

 ctcttcagct tctccatgtt cttcaacggc ctcgcggacc tggcgggctc 1000

 tacggcgggc gactacggcg gcctcgtggt cttctgcatc ttctttggca 1050

 tctcctacgg catggtgggg gccctgcagt tcgaggtgct catggccatc 1100

 gtgggcaccc acaagttctc cagtgccatt ggcctggtgc tgctgatgga 1150

 ggcggtggcc gtgctcgtcg ggcccccttc gggaggcaaa ctcctggatg 1200

 cgacccacgt ctacatgtac gtgttcatcc tggcgggggc cgaggtgctc 1250

 acctcctccc tgattttgct gctgggcaac ttcttctgca ttaggaagaa 1300

 gcccaaagag ccacagcctg aggtggcggc cgcggaggag gagaagctcc 1350

 acaagcctcc tgcagactcg ggggtggact tgcgggaggt ggagcatttc 1400

 ctgaaggctg agcctgagaa aaacggggag gtggttcaca ccccggaaac 1450

 aagtgtctga gtggctgggc ggggccggca ggcacaggga ggaggtacag 1500

 aagccggcaa cgcttgctat ttattttaca aactggactg gctcaggcag 1550

 ggccacggct gggctccagc tgccggccca gcggatcgtc gcccgatcag 1600

 tgttttgagg gggaaggtgg cggggtggga accgtgtcat tccagagtgg 1650

 atctgcggtg aagccaagcc gcaaggttac aaggcatcct caccaggggc 1700

 cccgcctgct gctcccaggt ggcctgcggc cactgctatg ctcaaggacc 1750

 tggaaaccca tgcttcgaga caacgtgact ttaatgggag ggtgggtggg 1800

 ccgcagacag gctggcaggg caggtgctgc gtggggccct ctccagcccg 1850

 tcctaccctg ggctcacatg gggcctgtgc ccacccctct tgagtgtctt 1900

 ggggacagct ctttccaccc ctggaagatg gaaataaacc tgcgtgtggg 1950

 tggagtgttc tcgtgccgaa ttcaaaaagc tt 1982

<210> 5600
<211> 465
<212> PRT
<213> Homo sapien

<400> 5600
 Met Gly Gly Ala Val Val Asp Glu Gly Pro Thr Gly Val Lys Ala
   1               5                  10                  15

 Pro Asp Gly Gly Trp Gly Trp Ala Val Leu Phe Gly Cys Phe Val
                  20                  25                  30

 Ile Thr Gly Phe Ser Tyr Ala Phe Pro Lys Ala Val Ser Val Phe
                  35                  40                  45

 Phe Lys Glu Leu Ile Gln Glu Phe Gly Ile Gly Tyr Ser Asp Thr
                  50                  55                  60

 Ala Trp Ile Ser Ser Ile Leu Leu Ala Met Leu Tyr Gly Thr Gly
                  65                  70                  75

 Pro Leu Cys Ser Val Cys Val Asn Arg Phe Gly Cys Arg Pro Val
                  80                  85                  90

 Met Leu Val Gly Gly Leu Phe Ala Ser Leu Gly Met Val Ala Ala
                  95                 100                 105

 Ser Phe Cys Arg Ser Ile Ile Gln Val Tyr Leu Thr Thr Gly Val
                 110                 115                 120

 Ile Thr Gly Leu Gly Leu Ala Leu Asn Phe Gln Pro Ser Leu Ile
                 125                 130                 135

 Met Leu Asn Arg Tyr Phe Ser Lys Arg Arg Pro Met Ala Asn Gly
                 140                 145                 150

 Leu Ala Ala Ala Gly Ser Pro Val Phe Leu Cys Ala Leu Ser Pro
                 155                 160                 165

 Leu Gly Gln Leu Leu Gln Asp Arg Tyr Gly Trp Arg Gly Gly Phe
                 170                 175                 180

 Leu Ile Leu Gly Gly Leu Leu Leu Asn Cys Cys Val Cys Ala Ala
                 185                 190                 195

 Leu Met Arg Pro Leu Val Val Thr Ala Gln Pro Gly Ser Gly Pro
                 200                 205                 210

 Pro Arg Pro Ser Arg Arg Leu Leu Asp Leu Ser Val Phe Arg Asp
                 215                 220                 225

 Arg Gly Phe Val Leu Tyr Ala Val Ala Ala Ser Val Met Val Leu
                 230                 235                 240

 Gly Leu Phe Val Pro Pro Val Phe Val Val Ser Tyr Ala Lys Asp
                 245                 250                 255

 Leu Gly Val Pro Asp Thr Lys Ala Ala Phe Leu Leu Thr Ile Leu
                 260                 265                 270

 Gly Phe Ile Asp Ile Phe Ala Arg Pro Ala Ala Gly Phe Val Ala
                 275                 280                 285

 Gly Leu Gly Lys Val Arg Pro Tyr Ser Val Tyr Leu Phe Ser Phe
                 290                 295                 300

 Ser Met Phe Phe Asn Gly Leu Ala Asp Leu Ala Gly Ser Thr Ala
                 305                 310                 315

 Gly Asp Tyr Gly Gly Leu Val Val Phe Cys Ile Phe Phe Gly Ile
                 320                 325                 330

 Ser Tyr Gly Met Val Gly Ala Leu Gln Phe Glu Val Leu Met Ala
                 335                 340                 345

 Ile Val Gly Thr His Lys Phe Ser Ser Ala Ile Gly Leu Val Leu
                 350                 355                 360

 Leu Met Glu Ala Val Ala Val Leu Val Gly Pro Pro Ser Gly Gly
                 365                 370                 375

 Lys Leu Leu Asp Ala Thr His Val Tyr Met Tyr Val Phe Ile Leu
                 380                 385                 390

 Ala Gly Ala Glu Val Leu Thr Ser Ser Leu Ile Leu Leu Leu Gly
                 395                 400                 405

 Asn Phe Phe Cys Ile Arg Lys Lys Pro Lys Glu Pro Gln Pro Glu
                 410                 415                 420

 Val Ala Ala Ala Glu Glu Glu Lys Leu His Lys Pro Pro Ala Asp
                 425                 430                 435

 Ser Gly Val Asp Leu Arg Glu Val Glu His Phe Leu Lys Ala Glu
                 440                 445                 450

 Pro Glu Lys Asn Gly Glu Val Val His Thr Pro Glu Thr Ser Val
                 455                 460                 465

<210> 5601
<211> 1168
<212> DNA
<213> Homo sapien

<400> 5601
 ggcacgaggc cccagccagc tgtcccgagt ctggactttc cctctgcccc 50

 tccccactct caggctggtg gggtggggaa agcagcccat tcctgggctc 100

 agagactccc accccagctc agagggagca ggggcccagc cagggacgga 150

 ccctcattcc tcccagggac cccagacctc tgtctctctc gggccttggc 200

 tccttgaact tttggccgcc atgtgcttcc cgaaggtcct ctctgatgac 250

 atgaagaagc tgaaggcccg aatggtaatg ctcctcccta cttctgctca 300

 ggggttgggg gcctgggtct cagcgtgtga cactgaggac actgtgggac 350

 acctgggacc ctggagggac aaggatccgg ccctttggtg ccaactctgc 400

 ctctcttcac agcaccaggc catagaaaga ttttatgata aaatgcaaaa 450

 tgcagaatca ggacgtggac aggtgatgtc gagcctggca gagctggagg 500

 acgacttcaa agagggctac ctggagacag tggcggctta ttatgaggag 550

 cagcacccag agctcactcc tctacttgaa aaagaaagag atggattacg 600

 gtgccgaggc aacagatccc ctgtcccgga tgttgaggat cccgcaaccg 650

 aggagcctgg ggagagcttt tgtgacaagg tcatgagatg gttccaggcc 700

 atgctgcagc ggctgcagac ctggtggcac ggggttctgg cctgggtgaa 750

 ggagaaggtg gtggccctgg tccatgcagt gcaggccctc tggaaacagt 800

 tccagagttt ctgctgctct ctgtcagagc tcttcatgtc ctctttccag 850

 tcctacggag ccccacgggg ggacaaggag gagctgacac cccagaagtg 900

 ctctgaaccc caatcctcaa aatgaagata ctgacaccac ctttgccctc 950

 cccgtcaccg cgcacccacc ctgacccctc cctcagctgt cctgtgcccc 1000

 gccctctccc gcacactcag tccccctgcc tggcgttcct gccgcagctc 1050

 tgacctggtg ctgtcgccct ggcatcttaa taaaacctgc ttatacttcc 1100

 ctggcagggg agataccctg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1150

 aaaaaaaaaa aaaaaaaa 1168

<210> 5602
<211> 234
<212> PRT
<213> Homo sapien

<400> 5602
 Met Cys Phe Pro Lys Val Leu Ser Asp Asp Met Lys Lys Leu Lys
   1               5                  10                  15

 Ala Arg Met Val Met Leu Leu Pro Thr Ser Ala Gln Gly Leu Gly
                  20                  25                  30

 Ala Trp Val Ser Ala Cys Asp Thr Glu Asp Thr Val Gly His Leu
                  35                  40                  45

 Gly Pro Trp Arg Asp Lys Asp Pro Ala Leu Trp Cys Gln Leu Cys
                  50                  55                  60

 Leu Ser Ser Gln His Gln Ala Ile Glu Arg Phe Tyr Asp Lys Met
                  65                  70                  75

 Gln Asn Ala Glu Ser Gly Arg Gly Gln Val Met Ser Ser Leu Ala
                  80                  85                  90

 Glu Leu Glu Asp Asp Phe Lys Glu Gly Tyr Leu Glu Thr Val Ala
                  95                 100                 105

 Ala Tyr Tyr Glu Glu Gln His Pro Glu Leu Thr Pro Leu Leu Glu
                 110                 115                 120

 Lys Glu Arg Asp Gly Leu Arg Cys Arg Gly Asn Arg Ser Pro Val
                 125                 130                 135

 Pro Asp Val Glu Asp Pro Ala Thr Glu Glu Pro Gly Glu Ser Phe
                 140                 145                 150

 Cys Asp Lys Val Met Arg Trp Phe Gln Ala Met Leu Gln Arg Leu
                 155                 160                 165

 Gln Thr Trp Trp His Gly Val Leu Ala Trp Val Lys Glu Lys Val
                 170                 175                 180

 Val Ala Leu Val His Ala Val Gln Ala Leu Trp Lys Gln Phe Gln
                 185                 190                 195

 Ser Phe Cys Cys Ser Leu Ser Glu Leu Phe Met Ser Ser Phe Gln
                 200                 205                 210

 Ser Tyr Gly Ala Pro Arg Gly Asp Lys Glu Glu Leu Thr Pro Gln
                 215                 220                 225

 Lys Cys Ser Glu Pro Gln Ser Ser Lys
                 230

<210> 5603
<211> 2574
<212> DNA
<213> Homo sapien

<400> 5603
 cctggcgcag ccgcagcagc gacgcgagcg aactcggccg ggcccgggcg 50

 cgcgggggcg ggacgcgcac gcggcgaggg cggcgggtga gccgggggcg 100

 gggacggggg cgggacgggg gcgaaggggg cggggacggg ggcgcccgcc 150

 ggcctaacgg gattaggagg gcgcgccacc cgcttccgct gcccgccggg 200

 gaatcccccg ggtggcgccc agggaagttc ccgaacgggc gggcataaaa 250

 gggcagccgc gccggcgccc cacagctctg cagctcgtgg cagcggcgca 300

 gcgctccagc catgtcgcgc ggcctccagc ttctgctcct gagctgcgcc 350

 tacagcctgg ctcccgcgac gccggaggtg aaggtggctt gctccgaaga 400

 tgtggacttg ccctgcaccg ccccctggga tccgcaggtt ccctacacgg 450

 tctcctgggt caagttattg gagggtggtg aagagaggat ggagacaccc 500

 caggaagacc acctcagggg acagcactat catcagaagg ggcaaaatgg 550

 ttctttcgac gcccccaatg aaaggcccta ttccctgaag atccgaaaca 600

 ctaccagctg caactcgggg acatacaggt gcactctgca ggacccggat 650

 gggcagagaa acctaagtgg caaggtgatc ttgagagtga caggatgccc 700

 tgcacagcgt aaagaagaga cttttaagaa atacagagcg gagattgtcc 750

 tgctgctggc tctggttatt ttctacttaa cactcatcat tttcacttgt 800

 aagtttgcac ggctacagag tatcttccca gatttttcta aagctggcat 850

 ggaacgagct tttctcccag ttacctcccc aaataagcat ttagggctag 900

 tgactcctca caagacagaa ctggtatgag caggatttct gcaggttctt 950

 cttcctgaag ctgaggctca ggggtgtgcc tgtctgttac actggaggag 1000

 agaagaatga gcctacgctg aagatggcat cctgtgaagt ccttcacctc 1050

 actgaaaaca tctggaaggg gatcccaccc cattttctgt gggcaggcct 1100

 cgaaaaccat cacatgacca catagcatga ggccactgct gcttctccat 1150

 ggccaccttt tcagcgatgt atgcagctat ctggtcaacc tcctggacat 1200

 tttttcagtc atataaaagc tatggtgaga tgcagctgga aaagggtctt 1250

 gggaaatatg aatgccccca gctggcccgt gacagactcc tgaggacagc 1300

 tgtcctcttc tgcatcttgg ggacatctct ttgaattttc tgtgttttgc 1350

 tgtaccagcc cagatgtttt acgtctggga gaaattgaca gatcaagctg 1400

 tgagacagtg ggaaatattt agcaaataat ttcctggtgt gaaggtcctg 1450

 ctattactaa ggagtaatct gtgtacaaag aaataacaag tcgatgaact 1500

 attccccagc agggtctttt catctgggaa agacatccat aaagaagcaa 1550

 taaagaagag tgccacattt atttttatat ctatatgtac ttgtcaaaga 1600

 aggtttgtgt ttttctgctt ttgaaatctg tatctgtagt gagatagcat 1650

 tgtgaactga caggcagcct ggacatagag agggagaaga agtcagagag 1700

 ggtgacaaga tagagagcta tttaatggcc ggctggaaat gctgggctga 1750

 cggtgcagtc tgggtgctcg cccacttgtc ccactatctg ggtgcatgat 1800

 cttgagcaag ttccttctgg tgtctgcttt ctccattgta aaccacaagg 1850

 ctgttgcatg ggctaatgaa gatcatatac gtgaaaatta tttgaaaaca 1900

 tataaagcac tatacagatt cgaaactcca ttgagtcatt atccttgcta 1950

 tgatgatggt gttttgggga tgagagggtg ctatccattt ctcatgtttt 2000

 ccattgtttg aaacaaagaa ggttaccaag aagcctttcc tgtagccttc 2050

 tgtaggaatt cttttgggga agtgaggaag ccaggtccac ggtctgttct 2100

 tgaagcagta gcctaacaca ctccaagata tggacacacg ggagccgctg 2150

 gcagaaggga cttcacgaag tgttgcatgg atgttttagc cattgttggc 2200

 tttcccttat caaacttggg cccttccctt cttggtttcc aaaggcattt 2250

 attgctgagt tatatgttca ctgtccccct aatattaggg agtaaaacgg 2300

 ataccaagtt gatttagtgt ttttacctct gtcttggctt tcatgttatt 2350

 aaacgtatgc atgtgaagaa gggtgttttt ctgttttata ttcaactcat 2400

 aagactttgg gataggaaaa atgagtaatg gttactaggc ttaatacctg 2450

 ggtgattaca taatctgtac aacgaacccc catgatgtaa gtttacctat 2500

 gtaacaaacc tgcacttata cccatgaact taaaatgaaa gttaaaaata 2550

 aaaaacatat acaaataaaa aaaa 2574

<210> 5604
<211> 205
<212> PRT
<213> Homo sapien

<400> 5604
 Met Ser Arg Gly Leu Gln Leu Leu Leu Leu Ser Cys Ala Tyr Ser
   1               5                  10                  15

 Leu Ala Pro Ala Thr Pro Glu Val Lys Val Ala Cys Ser Glu Asp
                  20                  25                  30

 Val Asp Leu Pro Cys Thr Ala Pro Trp Asp Pro Gln Val Pro Tyr
                  35                  40                  45

 Thr Val Ser Trp Val Lys Leu Leu Glu Gly Gly Glu Glu Arg Met
                  50                  55                  60

 Glu Thr Pro Gln Glu Asp His Leu Arg Gly Gln His Tyr His Gln
                  65                  70                  75

 Lys Gly Gln Asn Gly Ser Phe Asp Ala Pro Asn Glu Arg Pro Tyr
                  80                  85                  90

 Ser Leu Lys Ile Arg Asn Thr Thr Ser Cys Asn Ser Gly Thr Tyr
                  95                 100                 105

 Arg Cys Thr Leu Gln Asp Pro Asp Gly Gln Arg Asn Leu Ser Gly
                 110                 115                 120

 Lys Val Ile Leu Arg Val Thr Gly Cys Pro Ala Gln Arg Lys Glu
                 125                 130                 135

 Glu Thr Phe Lys Lys Tyr Arg Ala Glu Ile Val Leu Leu Leu Ala
                 140                 145                 150

 Leu Val Ile Phe Tyr Leu Thr Leu Ile Ile Phe Thr Cys Lys Phe
                 155                 160                 165

 Ala Arg Leu Gln Ser Ile Phe Pro Asp Phe Ser Lys Ala Gly Met
                 170                 175                 180

 Glu Arg Ala Phe Leu Pro Val Thr Ser Pro Asn Lys His Leu Gly
                 185                 190                 195

 Leu Val Thr Pro His Lys Thr Glu Leu Val
                 200                 205

<210> 5605
<211> 1999
<212> DNA
<213> Homo sapien

<400> 5605
 gccgggagcg ccgctccagc gaggcgcggg ctgtggggcc gccgcgtgcc 50

 tggccccgct cgcccgtgcc ggccgctcgc ccgccatgcc tggcttcgac 100

 tacaagttcc tggagaagcc caagcgacgg ctgctgtgcc cactgtgcgg 150

 gaagcccatg cgcgagcctg tgcaggtttc cacctgcggc caccgtttct 200

 gcgatacctg cctgcaggag ttcctcagtg aaggagtctt caagtgccct 250

 gaggaccagc ttcctctgga ctatgccaag atctacccag acccggagct 300

 ggaagtacaa gtattgggcc tgcctatccg ctgcatccac agtgaggagg 350

 gctgccgctg gagtgggcca ctacgtcatc tacagggcca cctgaatacc 400

 tgcagcttca atgtcattcc ctgccctaat cgctgcccca tgaagctgag 450

 ccgccgtgat ctacctgcac acttgcagca tgactgcccc aagcggcgcc 500

 tcaagtgcga gttttgtggc tgtgacttca gtggggaggc ctatgagagc 550

 catgagggta tgtgccccca ggagagtgtc tactgtgaga ataagtgtgg 600

 tgcccgcatg atgcggcggc tgctggccca gcatgccacc tctgagtgcc 650

 ccaagcgcac tcagccctgc acctactgca ctaaggagtt cgtctttgac 700

 accatccaga gccaccagta ccagtgccca aggctgcctg ttgcctgccc 750

 caaccaatgt ggtgtgggca ctgtggctcg ggaggacctg ccaggccatc 800

 tgaaggacag ctgtaacacc gccctggtgc tctgcccatt caaagactcc 850

 ggctgcaagc acaggtgccc taagctggca atggcacggc atgtggagga 900

 gagtgtgaag ccacatctgg ccatgatgtg tgccctggtg agccggcaac 950

 ggcaggagct gcaggagctt cggcgagagc tggaggagct atcagtgggc 1000

 agtgatggcg tgctcatctg gaagattggc agctatggac ggcggctaca 1050

 ggaggccaag gccaagccca accttgagtg cttcagccca gccttctaca 1100

 cacataagta tggttacaag ctgcaggtgt ctgcattcct caatggcaat 1150

 ggcagtggtg agggcacaca cctctcactg tacattcgtg tgctgcctgg 1200

 tgcctttgac aatctccttg agtggccctt tgcccgccgt gtcaccttct 1250

 ccctgctgga tcagagcgac cctgggctgg ctaaaccaca gcacgtcact 1300

 gagaccttcc accccgaccc aaactggaag aatttccaga agccaggcac 1350

 gtggcggggc tccctggatg agagttctct gggctttggt tatcccaagt 1400

 tcatctccca ccaggacatt cgaaagcgaa actatgtgcg ggatgatgca 1450

 gtcttcatcc gtgctgctgt tgaactgccc cggaagatcc tcagctgagt 1500

 gcaggtgggg ttcgagggga aaggacgatg gggcatgacc tcagtcaggc 1550

 actggctgaa cttggagagg gggccggacc cccgtcagct gcttctgctg 1600

 cctaggttct gttaccccat cctccctccc ccagccacca ccctcaggtg 1650

 cctccaattg gtgcttcagc cctggcccct gtggggaaca ggtcttgggg 1700

 tcatgaaggg ctggaaacaa gtgaccccag ggcctgtctc ccttcttggg 1750

 tagggcagac atgccttggt gccggtcaca ctctacacgg actgaggtgc 1800

 ctgctcaggt gctatgtccc aagagccata agggggtggg aattggggag 1850

 ggagaaaggg tagttcaaag agtctgtctt gagatctgat tttttccccc 1900

 tttacctagc tgtgccccct ctggttattt atttccttag tgccaggagg 1950

 gcacagcagg ggagccctga tttttaataa atccggaatt gtatttatt 1999

<210> 5606
<211> 470
<212> PRT
<213> Homo sapien

<400> 5606
 Met Pro Gly Phe Asp Tyr Lys Phe Leu Glu Lys Pro Lys Arg Arg
   1               5                  10                  15

 Leu Leu Cys Pro Leu Cys Gly Lys Pro Met Arg Glu Pro Val Gln
                  20                  25                  30

 Val Ser Thr Cys Gly His Arg Phe Cys Asp Thr Cys Leu Gln Glu
                  35                  40                  45

 Phe Leu Ser Glu Gly Val Phe Lys Cys Pro Glu Asp Gln Leu Pro
                  50                  55                  60

 Leu Asp Tyr Ala Lys Ile Tyr Pro Asp Pro Glu Leu Glu Val Gln
                  65                  70                  75

 Val Leu Gly Leu Pro Ile Arg Cys Ile His Ser Glu Glu Gly Cys
                  80                  85                  90

 Arg Trp Ser Gly Pro Leu Arg His Leu Gln Gly His Leu Asn Thr
                  95                 100                 105

 Cys Ser Phe Asn Val Ile Pro Cys Pro Asn Arg Cys Pro Met Lys
                 110                 115                 120

 Leu Ser Arg Arg Asp Leu Pro Ala His Leu Gln His Asp Cys Pro
                 125                 130                 135

 Lys Arg Arg Leu Lys Cys Glu Phe Cys Gly Cys Asp Phe Ser Gly
                 140                 145                 150

 Glu Ala Tyr Glu Ser His Glu Gly Met Cys Pro Gln Glu Ser Val
                 155                 160                 165

 Tyr Cys Glu Asn Lys Cys Gly Ala Arg Met Met Arg Arg Leu Leu
                 170                 175                 180

 Ala Gln His Ala Thr Ser Glu Cys Pro Lys Arg Thr Gln Pro Cys
                 185                 190                 195

 Thr Tyr Cys Thr Lys Glu Phe Val Phe Asp Thr Ile Gln Ser His
                 200                 205                 210

 Gln Tyr Gln Cys Pro Arg Leu Pro Val Ala Cys Pro Asn Gln Cys
                 215                 220                 225

 Gly Val Gly Thr Val Ala Arg Glu Asp Leu Pro Gly His Leu Lys
                 230                 235                 240

 Asp Ser Cys Asn Thr Ala Leu Val Leu Cys Pro Phe Lys Asp Ser
                 245                 250                 255

 Gly Cys Lys His Arg Cys Pro Lys Leu Ala Met Ala Arg His Val
                 260                 265                 270

 Glu Glu Ser Val Lys Pro His Leu Ala Met Met Cys Ala Leu Val
                 275                 280                 285

 Ser Arg Gln Arg Gln Glu Leu Gln Glu Leu Arg Arg Glu Leu Glu
                 290                 295                 300

 Glu Leu Ser Val Gly Ser Asp Gly Val Leu Ile Trp Lys Ile Gly
                 305                 310                 315

 Ser Tyr Gly Arg Arg Leu Gln Glu Ala Lys Ala Lys Pro Asn Leu
                 320                 325                 330

 Glu Cys Phe Ser Pro Ala Phe Tyr Thr His Lys Tyr Gly Tyr Lys
                 335                 340                 345

 Leu Gln Val Ser Ala Phe Leu Asn Gly Asn Gly Ser Gly Glu Gly
                 350                 355                 360

 Thr His Leu Ser Leu Tyr Ile Arg Val Leu Pro Gly Ala Phe Asp
                 365                 370                 375

 Asn Leu Leu Glu Trp Pro Phe Ala Arg Arg Val Thr Phe Ser Leu
                 380                 385                 390

 Leu Asp Gln Ser Asp Pro Gly Leu Ala Lys Pro Gln His Val Thr
                 395                 400                 405

 Glu Thr Phe His Pro Asp Pro Asn Trp Lys Asn Phe Gln Lys Pro
                 410                 415                 420

 Gly Thr Trp Arg Gly Ser Leu Asp Glu Ser Ser Leu Gly Phe Gly
                 425                 430                 435

 Tyr Pro Lys Phe Ile Ser His Gln Asp Ile Arg Lys Arg Asn Tyr
                 440                 445                 450

 Val Arg Asp Asp Ala Val Phe Ile Arg Ala Ala Val Glu Leu Pro
                 455                 460                 465

 Arg Lys Ile Leu Ser
                 470

<210> 5607
<211> 983
<212> DNA
<213> Homo sapien

<400> 5607
 gtggaattca tggcatctac ttcgtatgac tattgcagag tgcccatgga 50

 agacggggat aagcgctgta agcttctgct ggggatagga attctggtgc 100

 tcctgatcat cgtgattctg ggggtgccct tgattatctt caccatcaag 150

 gccaacagcg aggcctgccg ggacggcctt cgggcagtga tggagtgtcg 200

 caatgtcacc catctcctgc aacaagagct gaccgaggcc cagaagggct 250

 ttcaggatgt ggaggcccag gccgccacct gcaaccacac tgtgatggcc 300

 ctaatggctt ccctggatgc agagaaggcc caaggacaaa agaaagtgga 350

 ggagcttgag ggagagatca ctacattaaa ccataagctt caggacgcgt 400

 ctgcagaggt ggagcgactg agaagagaaa accaggtctt aagcgtgaga 450

 atcgcggaca agaagtacta ccccagctcc caggactcca gctccgctgc 500

 ggcgccccag ctgctgattg tgctgctggg cctcagcgct ctgctgcagt 550

 gagatcccag gaagctggca catcttggaa ggtccgtcct gctcggcttt 600

 tcgcttgaac attcccttga tctcatcagt tctgagcggg tcatggggca 650

 acacggttag cggggagagc acggggtagc cggagaaggg cctctggagc 700

 aggtctggag gggccatggg gcagtcctgg gtgtggggac acagtcgggt 750

 tgacccaggg ctgtctccct ccagagcctc cctccggaca atgagtcccc 800

 cctcttgtct cccaccctga gattgggcat ggggtgcggt gtggggggca 850

 tgtgctgcct gttgttatgg gttttttttg cggggggggt tgcttttttc 900

 tggggtcttt gagctccaaa aaataaacac ttcctttgag ggagagcaaa 950

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 983

<210> 5608
<211> 180
<212> PRT
<213> Homo sapien

<400> 5608
 Met Ala Ser Thr Ser Tyr Asp Tyr Cys Arg Val Pro Met Glu Asp
   1               5                  10                  15

 Gly Asp Lys Arg Cys Lys Leu Leu Leu Gly Ile Gly Ile Leu Val
                  20                  25                  30

 Leu Leu Ile Ile Val Ile Leu Gly Val Pro Leu Ile Ile Phe Thr
                  35                  40                  45

 Ile Lys Ala Asn Ser Glu Ala Cys Arg Asp Gly Leu Arg Ala Val
                  50                  55                  60

 Met Glu Cys Arg Asn Val Thr His Leu Leu Gln Gln Glu Leu Thr
                  65                  70                  75

 Glu Ala Gln Lys Gly Phe Gln Asp Val Glu Ala Gln Ala Ala Thr
                  80                  85                  90

 Cys Asn His Thr Val Met Ala Leu Met Ala Ser Leu Asp Ala Glu
                  95                 100                 105

 Lys Ala Gln Gly Gln Lys Lys Val Glu Glu Leu Glu Gly Glu Ile
                 110                 115                 120

 Thr Thr Leu Asn His Lys Leu Gln Asp Ala Ser Ala Glu Val Glu
                 125                 130                 135

 Arg Leu Arg Arg Glu Asn Gln Val Leu Ser Val Arg Ile Ala Asp
                 140                 145                 150

 Lys Lys Tyr Tyr Pro Ser Ser Gln Asp Ser Ser Ser Ala Ala Ala
                 155                 160                 165

 Pro Gln Leu Leu Ile Val Leu Leu Gly Leu Ser Ala Leu Leu Gln
                 170                 175                 180

<210> 5609
<211> 2646
<212> DNA
<213> Homo sapien

<400> 5609
 agtgcagacg cggctcctag cggatgggtg ctattgtgag gcggttgtag 50

 aagagtttcg tgagtgctcg cagctcatac ctgtggctgt gtatccgtgg 100

 ccacagctgg ttggcgtcgc cttgaaatcc caggccgtga ggagttagcg 150

 agccctgctc acactcggcg ctctggtttt cggtgggtgt gccctgcacc 200

 tgcctcttcc cccattctca ttaataaagg tatccatgga gaacactgaa 250

 aactcagtgg attcaaaatc cattaaaaat ttggaaccaa agatcataca 300

 tggaagcgaa tcaatggact ctggaatatc cctggacaac agttataaaa 350

 tggattatcc tgagatgggt ttatgtataa taattaataa taagaatttt 400

 cataaaagca ctggaatgac atctcggtct ggtacagatg tcgatgcagc 450

 aaacctcagg gaaacattca gaaacttgaa atatgaagtc aggaataaaa 500

 atgatcttac acgtgaagaa attgtggaat tgatgcgtga tgtttctaaa 550

 gaagatcaca gcaaaaggag cagttttgtt tgtgtgcttc tgagccatgg 600

 tgaagaagga ataatttttg gaacaaatgg acctgttgac ctgaaaaaaa 650

 taacaaactt tttcagaggg gatcgttgta gaagtctaac tggaaaaccc 700

 aaacttttca ttattcaggc ctgccgtggt acagaactgg actgtggcat 750

 tgagacagac agtggtgttg atgatgacat ggcgtgtcat aaaataccag 800

 tggaggccga cttcttgtat gcatactcca cagcacctgg ttattattct 850

 tggcgaaatt caaaggatgg ctcctggttc atccagtcgc tttgtgccat 900

 gctgaaacag tatgccgaca agcttgaatt tatgcacatt cttacccggg 950

 ttaaccgaaa ggtggcaaca gaatttgagt ccttttcctt tgacgctact 1000

 tttcatgcaa agaaacagat tccatgtatt gtttccatgc tcacaaaaga 1050

 actctatttt tatcactaaa gaaatggttg gttggtggtt ttttttagtt 1100

 tgtatgccaa gtgagaagat ggtatatttg gtactgtatt tccctctcat 1150

 tttgacctac tctcatgctg cagagggtac tttaagacat actccttcca 1200

 tcaaatagaa ccactatgaa gctacctcaa acttccagtc aggtagttgc 1250

 aattgaatta aattaggaat aaataaaaat ggatactggt gcagtcatta 1300

 tgagaggcaa tgattgttaa tttacagctt tcatgattag caagttacag 1350

 tgatgctgtg ctatgaattt tcaagtaatt gtgaaaaagt taaacattga 1400

 agtaatgaat ttttatgata ttccccccac ttaagactgt gtattctagt 1450

 tttgtcaaac tgtagaaatg atgatgtgga agaacttagg catctgtggg 1500

 catggtcaaa ggctcaaacc tttattttag aattgatata cacggatgac 1550

 ttaactgcat tttagaccat ttatctggga ttatggtttt gtgatgtttg 1600

 tcctgaacac ttttgttgta aaaaaataat aataataatg tttaatattg 1650

 agaaagaaac taatatttta tgtgagagaa agtgtgagca aactaacttg 1700

 acttttaagg ctaaaactta acattcatag aggggtggag ttttaactgt 1750

 aaggtgctac aatgcccctg gatctaccag cataaatatc ttctgatttg 1800

 tccctatgca tatcagttga gcttcatata ccagcaatat atctgaagag 1850

 ctattatata aaaaccccaa actgttgatt attagccagg taatgtgaat 1900

 aaattctata ggaacatatg aaaatacaac ttaaataata aacagtggaa 1950

 tataaggaaa gcaataaatg aatgggctga gctgcctgta acttgagagt 2000

 agatggtttg agcctgagca gagacatgac tcagcctgtt ccatgaaggc 2050

 agagccatgg accacgcagg aagggcctac agcccatttc tccatacgca 2100

 ctggtatgtg tggatgatgc tgccagggcg ccatcgccaa gtaagaaagt 2150

 gaagcaaatc agaaacttgt gaagtggaaa tgttctaaag gtggtgaggc 2200

 aataaaaatc atagtactct ttgtagcaaa attcttaagt atgttatttt 2250

 ctgttgaagt ttacaatcaa aggaaaatag taatgtttta tactgtttac 2300

 tgaaagaaaa agacctatga gcacatagga ctctagacgg catccagccg 2350

 gaggccagag ctgagcactc agcccgggag gcaggctcca ggcctcagca 2400

 ggtgcggagc cgtcactgca ccaagtctca ctggctgtca gtatgacatt 2450

 tcacgggaga tttcttgttg ctcaaaaaat gagctcgcat ttgtcaatga 2500

 cagtttcttt tttcttacta gacctgtaac ttttgtaaat acacacagca 2550

 tgtaatggta tcttaaagtg tgtttctatg tgacaatttt gtacaaattt 2600

 gttattttcc atttttattt caaaatatac attcaaactt aaaatt 2646

<210> 5610
<211> 277
<212> PRT
<213> Homo sapien

<400> 5610
 Met Glu Asn Thr Glu Asn Ser Val Asp Ser Lys Ser Ile Lys Asn
   1               5                  10                  15

 Leu Glu Pro Lys Ile Ile His Gly Ser Glu Ser Met Asp Ser Gly
                  20                  25                  30

 Ile Ser Leu Asp Asn Ser Tyr Lys Met Asp Tyr Pro Glu Met Gly
                  35                  40                  45

 Leu Cys Ile Ile Ile Asn Asn Lys Asn Phe His Lys Ser Thr Gly
                  50                  55                  60

 Met Thr Ser Arg Ser Gly Thr Asp Val Asp Ala Ala Asn Leu Arg
                  65                  70                  75

 Glu Thr Phe Arg Asn Leu Lys Tyr Glu Val Arg Asn Lys Asn Asp
                  80                  85                  90

 Leu Thr Arg Glu Glu Ile Val Glu Leu Met Arg Asp Val Ser Lys
                  95                 100                 105

 Glu Asp His Ser Lys Arg Ser Ser Phe Val Cys Val Leu Leu Ser
                 110                 115                 120

 His Gly Glu Glu Gly Ile Ile Phe Gly Thr Asn Gly Pro Val Asp
                 125                 130                 135

 Leu Lys Lys Ile Thr Asn Phe Phe Arg Gly Asp Arg Cys Arg Ser
                 140                 145                 150

 Leu Thr Gly Lys Pro Lys Leu Phe Ile Ile Gln Ala Cys Arg Gly
                 155                 160                 165

 Thr Glu Leu Asp Cys Gly Ile Glu Thr Asp Ser Gly Val Asp Asp
                 170                 175                 180

 Asp Met Ala Cys His Lys Ile Pro Val Glu Ala Asp Phe Leu Tyr
                 185                 190                 195

 Ala Tyr Ser Thr Ala Pro Gly Tyr Tyr Ser Trp Arg Asn Ser Lys
                 200                 205                 210

 Asp Gly Ser Trp Phe Ile Gln Ser Leu Cys Ala Met Leu Lys Gln
                 215                 220                 225

 Tyr Ala Asp Lys Leu Glu Phe Met His Ile Leu Thr Arg Val Asn
                 230                 235                 240

 Arg Lys Val Ala Thr Glu Phe Glu Ser Phe Ser Phe Asp Ala Thr
                 245                 250                 255

 Phe His Ala Lys Lys Gln Ile Pro Cys Ile Val Ser Met Leu Thr
                 260                 265                 270

 Lys Glu Leu Tyr Phe Tyr His
                 275

<210> 5611
<211> 2044
<212> DNA
<213> Homo sapien

<400> 5611
 ccggtcggat gccggaccgg gggcaccgct gaggcggtgg gtccccgacc 50

 tgcgagacag gtttggaagc ccccgctgcg cccagtccgt gcggaccgcg 100

 aggccgcggg cgggtggagg cgcgtctccg gcacgatgaa ggatttgggg 150

 gcagagcact tggcaggtca tgaaggggtc caacttctcg ggttgttgaa 200

 cgtctacctg gaacaagaag agagattcca acctcgagaa aaagggctga 250

 gtttgattga ggctaccccg gagaatgata acactttgtg tccaggattg 300

 agaaatgcca aagttgaaga tttaaggagt ttagccaact tttttggatc 350

 ttgcactgaa acttttgtcc tggctgtcaa tattttggac aggttcttgg 400

 ctcttatgaa ggtgaaacct aaacatttgt cttgcattgg agtctgttct 450

 tttttgctgg ctgctagaat agttgaagaa gactgcaata ttccatccac 500

 tcatgatgtg atccggatta gtcagtgtaa atgtactgct tctgacataa 550

 aacggatgga aaaaataatt tcagaaaaat tgcactatga attggaagct 600

 actactgcct taaacttttt gcacttatac catactatta tactttgtca 650

 tacttcagaa aggaaagaaa tactgagcct tgataaacta gaagctcagc 700

 tgaaagcttg caactgccga ctcatctttt caaaagcaaa accatctgta 750

 ttagccttgt gccttctcaa tttggaagtg gaaactttga aatctgttga 800

 attactggaa attctcttgc tagttaaaaa acattccaag attaatgaca 850

 ctgagttctt ctactggaga gagttggttt ctaaatgcct agccgagtat 900

 tcttctcctg aatgttgcaa accagatctt aagaagttgg tttggatcgt 950

 ttcaaggcgc acagcccaga acctccacaa cagctactat agtgttcctg 1000

 agctgccaac gatacctgag gggggttgtt ttgatgaaag tgaaagtgag 1050

 gactcttgtg aagatatgag ttgtggagag gagagtctca gcagctctcc 1100

 tcccagtgat caagagtgca ccttcttttt caacttcaaa gtggcacaaa 1150

 cactgtgctt tccatcttag aaatctgatt gttctgtcag aatttatatt 1200

 tacagggttt caaagcaata aatgggggaa taggtagttt cctggtttag 1250

 cccccatcta gtcaggaatt aatatactgg aatacctacc ttctatttgt 1300

 tattcagatc agatctggcc tattttcata tttatcctaa gccatcaaat 1350

 ggggtagtgc ctcttaaacc attaacagta ctttagacat tggcacttta 1400

 tttttctcgt agatctttag ctactttggg gaggagggaa ggtgctgata 1450

 ccttcaattt gttacttttc aagattttta aaaataacta gtgtagctta 1500

 tcttaaacat tttataaaac cttcagatgt ctttaagcag attggaagta 1550

 tgcaagtgct tccttagcag ggacagtgga taatccttaa tggtttatca 1600

 tagatttcac cctcccccct tctcagaaga gtgagtatgc tcttaaatgt 1650

 caaacacatt tttgttgttt tgttttttaa atgatcagtg tctatttgat 1700

 gtgatgcaga tcttataaat ttgggaatta taatattgac atttctgtga 1750

 tttttatata tgtaatgtct taattgagat ttgtgttaag gcagaaataa 1800

 ttaggctagg gctcttagtt ttcattccta ttgccccaag tattgtcaaa 1850

 ctatggtatt attttaatgt tactttaaaa atccataatc tgctagtttt 1900

 gcatgtactt atatgaaaac agtgcagtaa gttgaaaact cagtatctat 1950

 ggaattgata aatgttgatc tggtgtagta tattttatcc gcattttctt 2000

 atattaaaaa atgttctgca tgattacatt ttatttgcct ttgt 2044

<210> 5612
<211> 344
<212> PRT
<213> Homo sapien

<400> 5612
 Met Lys Asp Leu Gly Ala Glu His Leu Ala Gly His Glu Gly Val
   1               5                  10                  15

 Gln Leu Leu Gly Leu Leu Asn Val Tyr Leu Glu Gln Glu Glu Arg
                  20                  25                  30

 Phe Gln Pro Arg Glu Lys Gly Leu Ser Leu Ile Glu Ala Thr Pro
                  35                  40                  45

 Glu Asn Asp Asn Thr Leu Cys Pro Gly Leu Arg Asn Ala Lys Val
                  50                  55                  60

 Glu Asp Leu Arg Ser Leu Ala Asn Phe Phe Gly Ser Cys Thr Glu
                  65                  70                  75

 Thr Phe Val Leu Ala Val Asn Ile Leu Asp Arg Phe Leu Ala Leu
                  80                  85                  90

 Met Lys Val Lys Pro Lys His Leu Ser Cys Ile Gly Val Cys Ser
                  95                 100                 105

 Phe Leu Leu Ala Ala Arg Ile Val Glu Glu Asp Cys Asn Ile Pro
                 110                 115                 120

 Ser Thr His Asp Val Ile Arg Ile Ser Gln Cys Lys Cys Thr Ala
                 125                 130                 135

 Ser Asp Ile Lys Arg Met Glu Lys Ile Ile Ser Glu Lys Leu His
                 140                 145                 150

 Tyr Glu Leu Glu Ala Thr Thr Ala Leu Asn Phe Leu His Leu Tyr
                 155                 160                 165

 His Thr Ile Ile Leu Cys His Thr Ser Glu Arg Lys Glu Ile Leu
                 170                 175                 180

 Ser Leu Asp Lys Leu Glu Ala Gln Leu Lys Ala Cys Asn Cys Arg
                 185                 190                 195

 Leu Ile Phe Ser Lys Ala Lys Pro Ser Val Leu Ala Leu Cys Leu
                 200                 205                 210

 Leu Asn Leu Glu Val Glu Thr Leu Lys Ser Val Glu Leu Leu Glu
                 215                 220                 225

 Ile Leu Leu Leu Val Lys Lys His Ser Lys Ile Asn Asp Thr Glu
                 230                 235                 240

 Phe Phe Tyr Trp Arg Glu Leu Val Ser Lys Cys Leu Ala Glu Tyr
                 245                 250                 255

 Ser Ser Pro Glu Cys Cys Lys Pro Asp Leu Lys Lys Leu Val Trp
                 260                 265                 270

 Ile Val Ser Arg Arg Thr Ala Gln Asn Leu His Asn Ser Tyr Tyr
                 275                 280                 285

 Ser Val Pro Glu Leu Pro Thr Ile Pro Glu Gly Gly Cys Phe Asp
                 290                 295                 300

 Glu Ser Glu Ser Glu Asp Ser Cys Glu Asp Met Ser Cys Gly Glu
                 305                 310                 315

 Glu Ser Leu Ser Ser Ser Pro Pro Ser Asp Gln Glu Cys Thr Phe
                 320                 325                 330

 Phe Phe Asn Phe Lys Val Ala Gln Thr Leu Cys Phe Pro Ser
                 335                 340

<210> 5613
<211> 1490
<212> DNA
<213> Homo sapien

<400> 5613
 ggcacgaggc gcccccgcag ctgccgccgc cgccagggcc cggactcgga 50

 cgcgtggtag ccccaggatg ggtgagttca acgagaagaa gacaacatgt 100

 ggcaccgttt gcctcaagta cctgctgttt acctacaatt gctgcttctg 150

 gctggctggc ctggctgtca tggcagtggg catctggacg ctggccctca 200

 agagtgacta catcagcctg ctggcctcag gcacctacct ggccacagcc 250

 tacatcctgg tggtggcggg cactgtcgtc atggtgactg gggtcttggg 300

 ctgctgcgcc accttcaagg agcgtcggaa cctgctgcgc ctgtacttca 350

 tcctgctcct catcatcttt ctgctggaga tcatcgctgg tatcctcgcc 400

 tacgcctact accagcagct gaacacggag ctcaaggaga acctgaagga 450

 caccatgacc aagcgctacc accagccggg ccatgaggct gtgaccagcg 500

 ctgtggacca gctgcagcag gagttccact gctgtggcag caacaactca 550

 caggactggc gagacagtga gtggatccgc tcacaggagg ccggtggccg 600

 tgtggtccca gacagctgct gcaagacggt ggtggctctt tgtggacagc 650

 gagaccatgc ctccaacatc tacaaggtgg agggcggctg catcaccaag 700

 ttggagacct tcatccagga gcacctgagg gtcattgggg ctgtggggat 750

 cggcattgcc tgtgtgcagg tctttggcat gatcttcacg tgctgcctgt 800

 acaggagtct caagctggag cactactgac cctgccttgg gccttgctgc 850

 tgctgcaccc aactactgag ctgagaccac tgagtaccag gggctgggct 900

 ccctgatgac acccaccctg tgccatcacc ataacctctg gggaccccaa 950

 cctcagaggc agcttcaagt gccttttgct gcgcaccaat gcccagcagg 1000

 ggaggtgagg ggggctggcg gggcgaagtt tggggggtgt tttgtggggc 1050

 tccccggaca tactctctgc ctggtggtca gatgcaggtt ggaaggggcc 1100

 ttgctgagtg gcgcaaggcc gagcgttccc agcaggggga gaaacccttc 1150

 acaccccagg cccttcagga actggggctt tgccttgcag ccacatggcc 1200

 ccatcccagt tggggaagcc aggtgagctc tgacccttgg gcctgggcct 1250

 ctgcccctcc caacccagcc gtcgtctccc tcgacagcgc ccctgctgtc 1300

 ttccccaccg cagtcaccac cacccgaaat gccacgtggt cactgtgcac 1350

 tgccctgttc atgtgcctct gcggggcagg gccttcctgg ttttgtacac 1400

 tgctgtaccc agatgcctac aaccatccct gccacataca ggtgctcaat 1450

 aaacacttgt agagcagatg gaaaaaaaaa aaaaaaaaaa 1490

<210> 5614
<211> 253
<212> PRT
<213> Homo sapien

<400> 5614
 Met Gly Glu Phe Asn Glu Lys Lys Thr Thr Cys Gly Thr Val Cys
   1               5                  10                  15

 Leu Lys Tyr Leu Leu Phe Thr Tyr Asn Cys Cys Phe Trp Leu Ala
                  20                  25                  30

 Gly Leu Ala Val Met Ala Val Gly Ile Trp Thr Leu Ala Leu Lys
                  35                  40                  45

 Ser Asp Tyr Ile Ser Leu Leu Ala Ser Gly Thr Tyr Leu Ala Thr
                  50                  55                  60

 Ala Tyr Ile Leu Val Val Ala Gly Thr Val Val Met Val Thr Gly
                  65                  70                  75

 Val Leu Gly Cys Cys Ala Thr Phe Lys Glu Arg Arg Asn Leu Leu
                  80                  85                  90

 Arg Leu Tyr Phe Ile Leu Leu Leu Ile Ile Phe Leu Leu Glu Ile
                  95                 100                 105

 Ile Ala Gly Ile Leu Ala Tyr Ala Tyr Tyr Gln Gln Leu Asn Thr
                 110                 115                 120

 Glu Leu Lys Glu Asn Leu Lys Asp Thr Met Thr Lys Arg Tyr His
                 125                 130                 135

 Gln Pro Gly His Glu Ala Val Thr Ser Ala Val Asp Gln Leu Gln
                 140                 145                 150

 Gln Glu Phe His Cys Cys Gly Ser Asn Asn Ser Gln Asp Trp Arg
                 155                 160                 165

 Asp Ser Glu Trp Ile Arg Ser Gln Glu Ala Gly Gly Arg Val Val
                 170                 175                 180

 Pro Asp Ser Cys Cys Lys Thr Val Val Ala Leu Cys Gly Gln Arg
                 185                 190                 195

 Asp His Ala Ser Asn Ile Tyr Lys Val Glu Gly Gly Cys Ile Thr
                 200                 205                 210

 Lys Leu Glu Thr Phe Ile Gln Glu His Leu Arg Val Ile Gly Ala
                 215                 220                 225

 Val Gly Ile Gly Ile Ala Cys Val Gln Val Phe Gly Met Ile Phe
                 230                 235                 240

 Thr Cys Cys Leu Tyr Arg Ser Leu Lys Leu Glu His Tyr
                 245                 250

<210> 5615
<211> 4289
<212> DNA
<213> Homo sapien

<400> 5615
 gatcaatact gaggccgcgt cgaccccctt gagccgagac ccccccccag 50

 cccagccccc accccacccc ccgcacacgc cccacccccc ccacgaccca 100

 gcctcatacc gcaccagctg aggcacccaa gaggattacc ccctggggcc 150

 ctctcccgcc ccccaaaaaa gagaagatcc cctctcctgg cccatccctt 200

 cccttcttcc ctcccccctc cccccgaact ttccctctcg catgcttttc 250

 ccctgcacca cggatcgcct ctcggatgcc gcttgcctgg aagctgcgtt 300

 aggagcgagc ggcggcggtg gcggcggtgg cggcggcggc ggcagctcgg 350

 gagtgctatg accggcaaac tcgccgagaa gctgccggtg accatgagca 400

 gtttgctaaa ccaactgcct gacaatctgt accccgagga gatccccagc 450

 gcgctcaacc tcttctccgg cagcagcgac tcggtagtcc attacaatca 500

 gatggctaca gagaatgtaa tggacatcgg tctgaccaac gagaagccca 550

 acccggaact ctcttactcc ggctccttcc agccagcccc cgggaacaag 600

 accgtgacct acttgggaaa gttcgccttc gactcccctt ccaactggtg 650

 ccaggacaac atcattagcc tcatgagcgc cggcatcttg ggggtgcccc 700

 cggcttcagg ggcgctaagc acgcagacgt ccacggccag catggtgcag 750

 ccaccgcagg gtgacgtgga ggccatgtat cccgcgctac ccccctactc 800

 caactgcggc gacctctact cagagcccgt gtctttccac gacccccagg 850

 gcaatcccgg gctcgcctat tccccccagg attaccaatc ggccaagccg 900

 gcgttggaca gcaatctctt ccccatgatt cctgactaca acctctacca 950

 ccaccccaac gacatgggct ccattccgga gcacaagccc ttccagggca 1000

 tggaccccat ccgggtcaac ccgcccccta ctacccctct ggagaccatc 1050

 aaggcattca aagacaagca gatccacccg ggctttggca gcctgcccca 1100

 gccgccgctc accctcaagc ccatccggcc ccgcaagtac cccaaccggc 1150

 ctagcaagac accgctccac gaacggcccc acgcgtgccc ggccgagggc 1200

 tgcgaccgcc gtttcagccg ttcggacgag ctgacccggc acctgcgcat 1250

 ccacacgggc cacaagccct tccagtgccg gatctgcatg cggagcttca 1300

 gccgcagcga ccacctcacc actcacatcc gcactcatac gggcgagaag 1350

 ccctttgcct gcgagttctg cgggcgcaag tttgcgcgca gcgacgagcg 1400

 caagcgccac gccaagatcc acctcaagca aaaggagaag aaggcggaga 1450

 agggcggtgc accctctgca tcctcggcgc cccccgtgtc gctggccccc 1500

 gtggtcacca cctgcgcctg aggatcgggc ccccagatcc ccacttttcc 1550

 cctccagtgc ctcccggctg ctagcctgaa agcagcggga aagccagcca 1600

 cggaggcgta ggggccgcgc cctggcctct ccatggacgt gcggcccctt 1650

 gcttcccctt cgatgccccc ggttcccaac ctttcacgcc ggccagcggt 1700

 caggggccag ggctggaggc gccttcccct cgcggtcccc cacttagcca 1750

 aggcgtgggg gcggaaaggt ggcgtctagc ccgctttgtt cagttcggat 1800

 cgccttgatc caggggccgc cgggccgcgc caaggacctg caagggactg 1850

 aaggcggagc ccatccaacc ctcgcccgac ccaaacacct cattgtttcc 1900

 cccacgtctc cctctatacc ccctcgaaga ctcgagaggg ggagggggta 1950

 aggagcgcac caaagcgcag agcttgctgc ccgccgcacg cacgcgcgcc 2000

 tgcgtgcggg gatgcgcgcg agtgtgtgcg tgctcgcgtg tgtgtgtatg 2050

 tgtgtgtgtg agtgtgtgtg tgtgcgcgcg cgcaagcgtg tgtgtttaag 2100

 actcttgagc tgaactgggc tgtgtttacc ccaaactctt ccccacctcg 2150

 ggtccccaag ccgctgggag atgtcccatg ctgggggtcc gcacgtggct 2200

 ggaggaggtg gtcttccatc cgctctgaaa tcatgtttct tagagaaatg 2250

 cctcggatgc cgccgacgcg gtgctgctgc cgccgcttcg ggtttggccc 2300

 ctcagaaccc ctccttttct gagcgcttcc ctcttaggcc tcagggcagt 2350

 ttgatctgtg gggagaaaga gcagccatcg ctgagcctgc cttttaaaat 2400

 atatgtgtat ttccttagcc ccactctaag aaatctatgt tcctgagttt 2450

 gccccctgcc ctcccactcc ttcccctttt cccctctaaa ccttctccca 2500

 tctctttcaa aatcttttcc cagaaaggca ggcttcaacc agccactcca 2550

 gctttgtgtc ttctctcaat tacatagcaa tttctccttc ccaccatcat 2600

 ggggaagctg gctctgcttt tgccctttgt catcaccaac acaacagata 2650

 gaatttaaat ataagtatat ggtgtgcgtg tgtatgtatg tgtatgtata 2700

 tgcatgcatg tgtataaaga tgcacatgcg tacatataca taacatacac 2750

 acaatatgta ttcctagcaa aataaaatct ctaaggtact tggttatcca 2800

 gtgcagtgca ccggaataaa gagaatttgt aggcgtatac agctttaaat 2850

 gatttatttt ttatgaaaat gttaactgat gagattatat ctacatacgt 2900

 gtgttatgtg tgtggatata gatgcacaca tatctgtaca tatacatgtg 2950

 agtgtacata tatacacata tacacatcta tgtatggata tgtgtgtata 3000

 cacatataca catctctgtc caaaatttcc tcaaagatat ggggattttt 3050

 tcatgaatcc atgtggatga atgaggtgtc tcctttccat acccagtctc 3100

 accttctccc caccctacct cacctcttct caggcacccc tcttccccag 3150

 ctgtcctgcc agcccttctc gtacagggtg gctcctttga agtggagtaa 3200

 tagggaaggt tgctctctgc cacagcttgc agcatggtct tgactgaatg 3250

 tactgttcct gttagcgtta cttctcctgt ggtcagtaag ttgcccagag 3300

 agaaggaaca aaggtctgga gtttacagaa tgtctgtttt taaagtcact 3350

 ttatgcgttt tccacttttt tcttttttaa gaaaaagaag taccattttt 3400

 gttttgtttt gttttgattt ttggtggtgg ataaataata ctaaaaggac 3450

 tctagtggaa aggggggata tcgaagagca gggggttgtg aatttccagg 3500

 tacttggact ttttgtagaa gtagagagaa gaagatgaag tttgccagga 3550

 gggcccatat tttttcagct gaagggtaaa atctttcttt gcagagacag 3600

 tattttgctg aatacttttt ataatgtgat gattattaaa aaagcaaaaa 3650

 ttttggtcac ttccaagcta gaaggaggaa tcagataccc tttaatattt 3700

 tttcctcgct ccttctggta tatgcatgtc actgcatgat aattgagttt 3750

 tcctttgttt taataaaact gttctcagac attaagctaa actaagagaa 3800

 aaataacttt gttgccaaaa ggttgtgcta tccagatttt ttatatgtct 3850

 gcatgtttaa aaaaaaaaaa gcaacaaaag aaaatgcact ctaacttatg 3900

 tgaactgaga gaaaaaaatc aggttttaaa caggaaaacc tatggggaat 3950

 gatatttttt gaaagacttt tgtataaagt tgagtactta gaaaaaagac 4000

 aaaccagatg taatatattt tgtggatgtt tttatttctt ggatttatag 4050

 taccttatac taaggttaaa aaaatatgct tgatattgtg aaaaggtgaa 4100

 attcttcacc aacatttcat ttgctccttt gtcatattgt aatgccaata 4150

 taatatagtt aatgaaaaca gcatttttaa aaaccgaaat attgaaatgg 4200

 tgtaatgttg taccatttgc actgtgagca aatgctaata cagtaaatat 4250

 attgtgtttg ctgacaatca aaaaaaaaaa aaaaaaaaa 4289

<210> 5616
<211> 387
<212> PRT
<213> Homo sapien

<400> 5616
 Met Thr Gly Lys Leu Ala Glu Lys Leu Pro Val Thr Met Ser Ser
   1               5                  10                  15

 Leu Leu Asn Gln Leu Pro Asp Asn Leu Tyr Pro Glu Glu Ile Pro
                  20                  25                  30

 Ser Ala Leu Asn Leu Phe Ser Gly Ser Ser Asp Ser Val Val His
                  35                  40                  45

 Tyr Asn Gln Met Ala Thr Glu Asn Val Met Asp Ile Gly Leu Thr
                  50                  55                  60

 Asn Glu Lys Pro Asn Pro Glu Leu Ser Tyr Ser Gly Ser Phe Gln
                  65                  70                  75

 Pro Ala Pro Gly Asn Lys Thr Val Thr Tyr Leu Gly Lys Phe Ala
                  80                  85                  90

 Phe Asp Ser Pro Ser Asn Trp Cys Gln Asp Asn Ile Ile Ser Leu
                  95                 100                 105

 Met Ser Ala Gly Ile Leu Gly Val Pro Pro Ala Ser Gly Ala Leu
                 110                 115                 120

 Ser Thr Gln Thr Ser Thr Ala Ser Met Val Gln Pro Pro Gln Gly
                 125                 130                 135

 Asp Val Glu Ala Met Tyr Pro Ala Leu Pro Pro Tyr Ser Asn Cys
                 140                 145                 150

 Gly Asp Leu Tyr Ser Glu Pro Val Ser Phe His Asp Pro Gln Gly
                 155                 160                 165

 Asn Pro Gly Leu Ala Tyr Ser Pro Gln Asp Tyr Gln Ser Ala Lys
                 170                 175                 180

 Pro Ala Leu Asp Ser Asn Leu Phe Pro Met Ile Pro Asp Tyr Asn
                 185                 190                 195

 Leu Tyr His His Pro Asn Asp Met Gly Ser Ile Pro Glu His Lys
                 200                 205                 210

 Pro Phe Gln Gly Met Asp Pro Ile Arg Val Asn Pro Pro Pro Thr
                 215                 220                 225

 Thr Pro Leu Glu Thr Ile Lys Ala Phe Lys Asp Lys Gln Ile His
                 230                 235                 240

 Pro Gly Phe Gly Ser Leu Pro Gln Pro Pro Leu Thr Leu Lys Pro
                 245                 250                 255

 Ile Arg Pro Arg Lys Tyr Pro Asn Arg Pro Ser Lys Thr Pro Leu
                 260                 265                 270

 His Glu Arg Pro His Ala Cys Pro Ala Glu Gly Cys Asp Arg Arg
                 275                 280                 285

 Phe Ser Arg Ser Asp Glu Leu Thr Arg His Leu Arg Ile His Thr
                 290                 295                 300

 Gly His Lys Pro Phe Gln Cys Arg Ile Cys Met Arg Ser Phe Ser
                 305                 310                 315

 Arg Ser Asp His Leu Thr Thr His Ile Arg Thr His Thr Gly Glu
                 320                 325                 330

 Lys Pro Phe Ala Cys Glu Phe Cys Gly Arg Lys Phe Ala Arg Ser
                 335                 340                 345

 Asp Glu Arg Lys Arg His Ala Lys Ile His Leu Lys Gln Lys Glu
                 350                 355                 360

 Lys Lys Ala Glu Lys Gly Gly Ala Pro Ser Ala Ser Ser Ala Pro
                 365                 370                 375

 Pro Val Ser Leu Ala Pro Val Val Thr Thr Cys Ala
                 380                 385

<210> 5617
<211> 1776
<212> DNA
<213> Homo sapien

<400> 5617
 gggggctgta gctggtgaga ggaagtccta gaggctatgg acactctgct 50

 gctgggatca ccgagatgag cagcagctgc tcagggctga gcagggtcct 100

 ggtggccgtg gctacagccc tggtgtctgc ctcctccccc tgcccccagg 150

 cctggggccc cccaggggtc cagtatgggc agccaggcag gtccgtgaag 200

 ctgtgttgtc ctggagtgac tgccggggac ccagtgtcct ggtttcggga 250

 tggggagcca aagctgctcc agggacctga ctctgggcta gggcatgaac 300

 tggtcctggc ccaggcagac agcactgatg agggcaccta catctgccag 350

 accctggatg gtgcacttgg gggcacagtg accctgcagc tgggctaccc 400

 tccagcccgc cctgttgtct cctgccaagc agccgactat gagaacttct 450

 cttgcacttg gagtcccagc cagatcagcg gtttacccac ccgctacctc 500

 acctcctaca ggaagaagac agtcctagga gctgatagcc agaggaggag 550

 tccatccaca gggccctggc catgcccaca ggatccccta ggggctgccc 600

 gctgtgttgt ccacggggct gagttctgga gccagtaccg gattaatgtg 650

 actgaggtga acccactggg tgccagcaca cgcctgctgg atgtgagctt 700

 gcagagcatc ttgcgccctg acccacccca gggcctgcgg gtagagtcag 750

 taccaggtta cccccgacgc ctgcgagcca gctggacata ccctgcctcc 800

 tggccgtgcc agccccactt cctgctcaag ttccgtttgc agtaccgtcc 850

 ggcgcagcat ccagcctggt ccacggtgga gccagctgga ctggaggagg 900

 tgatcacaga tgctgtggct gggctgcccc atgctgtacg agtcagtgcc 950

 cgggactttc tagatgctgg cacctggagc acctggagcc cggaggcctg 1000

 gggaactccg agcactggga ccataccaaa ggagatacca gcatggggcc 1050

 agctacacac gcagccagag gtggagcctc aggtggacag ccctgctcct 1100

 ccaaggccct ccctccaacc acaccctcgg ctacttgatc acagggactc 1150

 tgtggagcag gtagctgtgc tggcgtcttt gggaatcctt tctttcctgg 1200

 gactggtggc tggggccctg gcactggggc tctggctgag gctgagacgg 1250

 ggtgggaagg atggatcccc aaagcctggg ttcttggcct cagtgattcc 1300

 agtggacagg cgtccaggag ctccaaacct gtagaggacc caggagggct 1350

 tcggcagatt ccacctataa ttctgtcttg ctggtgtgga tagaaaccag 1400

 gcaggacagt agatccctat ggttggatct cagctggaag ttctgtttgg 1450

 agcccatttc tgtgagaccc tgtatttcaa atttgcagct gaaaggtgct 1500

 tgtacctctg atttcacccc agagttggag ttctgctcaa ggaacgtgtg 1550

 taatgtgtac atctgtgtcc atgtgtgacc atgtgtctgt gaggcaggga 1600

 acatgtattc tctgcatgca tgtatgtagg tgcctgggga gtgtgtgtgg 1650

 gtccttggct cttggccttt ccccttgcag gggttgtgca ggtgtgaata 1700

 aagagaataa ggaagttctt ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa aaaaaa 1776

<210> 5618
<211> 422
<212> PRT
<213> Homo sapien

<400> 5618
 Met Ser Ser Ser Cys Ser Gly Leu Ser Arg Val Leu Val Ala Val
   1               5                  10                  15

 Ala Thr Ala Leu Val Ser Ala Ser Ser Pro Cys Pro Gln Ala Trp
                  20                  25                  30

 Gly Pro Pro Gly Val Gln Tyr Gly Gln Pro Gly Arg Ser Val Lys
                  35                  40                  45

 Leu Cys Cys Pro Gly Val Thr Ala Gly Asp Pro Val Ser Trp Phe
                  50                  55                  60

 Arg Asp Gly Glu Pro Lys Leu Leu Gln Gly Pro Asp Ser Gly Leu
                  65                  70                  75

 Gly His Glu Leu Val Leu Ala Gln Ala Asp Ser Thr Asp Glu Gly
                  80                  85                  90

 Thr Tyr Ile Cys Gln Thr Leu Asp Gly Ala Leu Gly Gly Thr Val
                  95                 100                 105

 Thr Leu Gln Leu Gly Tyr Pro Pro Ala Arg Pro Val Val Ser Cys
                 110                 115                 120

 Gln Ala Ala Asp Tyr Glu Asn Phe Ser Cys Thr Trp Ser Pro Ser
                 125                 130                 135

 Gln Ile Ser Gly Leu Pro Thr Arg Tyr Leu Thr Ser Tyr Arg Lys
                 140                 145                 150

 Lys Thr Val Leu Gly Ala Asp Ser Gln Arg Arg Ser Pro Ser Thr
                 155                 160                 165

 Gly Pro Trp Pro Cys Pro Gln Asp Pro Leu Gly Ala Ala Arg Cys
                 170                 175                 180

 Val Val His Gly Ala Glu Phe Trp Ser Gln Tyr Arg Ile Asn Val
                 185                 190                 195

 Thr Glu Val Asn Pro Leu Gly Ala Ser Thr Arg Leu Leu Asp Val
                 200                 205                 210

 Ser Leu Gln Ser Ile Leu Arg Pro Asp Pro Pro Gln Gly Leu Arg
                 215                 220                 225

 Val Glu Ser Val Pro Gly Tyr Pro Arg Arg Leu Arg Ala Ser Trp
                 230                 235                 240

 Thr Tyr Pro Ala Ser Trp Pro Cys Gln Pro His Phe Leu Leu Lys
                 245                 250                 255

 Phe Arg Leu Gln Tyr Arg Pro Ala Gln His Pro Ala Trp Ser Thr
                 260                 265                 270

 Val Glu Pro Ala Gly Leu Glu Glu Val Ile Thr Asp Ala Val Ala
                 275                 280                 285

 Gly Leu Pro His Ala Val Arg Val Ser Ala Arg Asp Phe Leu Asp
                 290                 295                 300

 Ala Gly Thr Trp Ser Thr Trp Ser Pro Glu Ala Trp Gly Thr Pro
                 305                 310                 315

 Ser Thr Gly Thr Ile Pro Lys Glu Ile Pro Ala Trp Gly Gln Leu
                 320                 325                 330

 His Thr Gln Pro Glu Val Glu Pro Gln Val Asp Ser Pro Ala Pro
                 335                 340                 345

 Pro Arg Pro Ser Leu Gln Pro His Pro Arg Leu Leu Asp His Arg
                 350                 355                 360

 Asp Ser Val Glu Gln Val Ala Val Leu Ala Ser Leu Gly Ile Leu
                 365                 370                 375

 Ser Phe Leu Gly Leu Val Ala Gly Ala Leu Ala Leu Gly Leu Trp
                 380                 385                 390

 Leu Arg Leu Arg Arg Gly Gly Lys Asp Gly Ser Pro Lys Pro Gly
                 395                 400                 405

 Phe Leu Ala Ser Val Ile Pro Val Asp Arg Arg Pro Gly Ala Pro
                 410                 415                 420

 Asn Leu


<210> 5619
<211> 8615
<212> DNA
<213> Homo sapien

<400> 5619
 gagtttgcag aagagagtct tcccgagaag gcagaacgag ggtgtgtgga 50

 gcactgcggg cgagatggag ctgagggaag gcagagctgg gtctcactct 100

 gttgcccagg ctggagttca gcggtgcaat cccggctcac tgcagccttg 150

 actccgtgag ctcagggact catgaagtgg cagctaagcc ctgtccagtg 200

 gccacccgtc agccaagggc cagagaccag gaaaggaaga aaggcagctt 250

 cacttcctct ttgaggatgg agtcgcacag ccgcgctgga aagagcagaa 300

 aatctgcaaa atttcggtcc atctccaggt ccctgatgct ctgtaatgct 350

 aagaccagtg atgatggctc tagccctgat gagaaatatc ctgatccctt 400

 tgagatttcc ttggcccagg gcaaggaggg aattttccac tcatctgtgc 450

 agctggcaga cacatcggag gctgggccca gcagtgttcc tgatctagca 500

 ctggcctcgg aggctgctca actccaagca gctgggaatg atcgaggcaa 550

 gacctgtagg aggatattct tcatgaagga atcttccaca gcttcctctc 600

 gagaaaagcc tggaaaacta gaagcacaaa gtagtaactt cctgtttcct 650

 aaagcctgcc accaaagggc acgcagcaac tcaaccagtg ttaatcccta 700

 ttgcacaaga gaaattgatt ttccaatgac caagaaatct gcagcgccca 750

 cggacaggca gccttactct ctctgcagta acaggaagtc cctctctcaa 800

 caattggact gtccagcagg aaaggctgcg ggaacttcga gaccaacacg 850

 gtccctgagc acagctcagc tcgtgcagcc atctgggggc ctccaggctt 900

 cagtcatctc caacatcgtg ctgatgaagg gccaggctaa gggtctgggc 950

 ttcagcatcg ttgggggaaa agacagcatt tatggcccca ttgggattta 1000

 cgtcaaaacc atttttgcag ggggagcagc agcagccgat ggaaggctac 1050

 aggaaggtga tgaaattctg gagctcaatg gtgaatcaat ggctggacta 1100

 acacatcagg atgctttgca gaagttcaag caagccaaaa aggggctcct 1150

 caccctcacc gtgagaaccc gcctgacggc gcctccttcc ctgtgcagcc 1200

 acctgtctcc cccactgtgc cgctccctga gctccagcac ttgtatcacc 1250

 aaggacagca gctccttcgc cttggaaagc ccctcggctc ccatcagcac 1300

 cgccaagccc aattacagaa tcatggtgga ggtttctctg cagaaagagg 1350

 ccggcgtggg cctgggcatc ggcctgtgca gcgttcccta cttccaatgc 1400

 atctctggca ttttcgtcca cacgctgtca ccaggatccg tggcgcacct 1450

 ggacggacgt ctccggtgtg gggacgagat tgtggaaatc agtgattccc 1500

 ctgtgcactg cctgacgctc aatgaagtct acacgatcct gagtcactgt 1550

 gatcccggtc cagtccccat cattgttagc cgacatccag acccacaggt 1600

 ctctgaacag caactcaaag aagctgtggc ccaggctgtg gaaaacacca 1650

 agtttggaaa ggagaggcat cagtggagtc tggaaggtgt caaaaggctg 1700

 gaaagcagtt ggcacgggcg gcccaccttg gagaaggaac gagagaagaa 1750

 ctcagcaccc ccgcatcgca gggctcagaa ggtcatgatc cgctccagca 1800

 gtgacagcag ctacatgtct gggtccccag ggggaagtcc tgggagtggc 1850

 agtgctgaga agccgtcctc tgacgtggac atcagcacac acagccccag 1900

 cttgcctctg gcacgggagc cagtggtgct ttctatagca tcctccaggc 1950

 tgccccagga gagcccaccc ctcccagaga gccgggacag ccacccgccg 2000

 ctgagactga agaaatcctt tgagattttg gaagcgagag agctgctgcc 2050

 actgctgcta ccacaggaag acacagcagg gagaagccct agtgcctctg 2100

 ccggctgccc aggacctggt atcggcccac agaccaagtc ctccacagag 2150

 ggcgagccag ggtggagaag agccagccca gtgacccaaa catccccgat 2200

 aaaacaccca ctgcttaaga ggcaggctcg gatggactat agctttgata 2250

 ccacagccga agacccttgg gttaggattt ctgactgcat caaaaactta 2300

 tttagcccca tcatgagtga gaaccatggc cacatgcctc tacagcccaa 2350

 tgccagcctg aatgaagaag aagggacaca gggccaccca gatgggaccc 2400

 caccaaagct ggacaccgcc aatggcactc ccaaagttta caagtcagca 2450

 gacagcagca ctgtgaagaa aggtcctcct gtggctccca agccagcctg 2500

 gtttcgccaa agcttgaaag gtttgaggaa tcgtgcttca gacccaagag 2550

 ggctccctga tcctgccttg tccacccagc cagcacctgc ttccagggag 2600

 cacctaggat cacacatccg ggcctcctcc tcctcctcct ccatcaggca 2650

 gagaatcagc tcctttgaaa cctttggctc ctctcaactg cctgacaaag 2700

 gagcccagag actgagcctc cagccctcct ctggggaggc agcaaaacct 2750

 cttgggaagc atgaggaagg acggttttct ggactcttgg ggcgaggggc 2800

 tgcacccact cttgtgcccc agcagcctga gcaagtactg tcctcggggt 2850

 cccctgcagc ctccgaggcc agagacccag gtgtgtctga gtcccctccc 2900

 ccagggcggc agcccaatca gaaaactctc ccccctggcc cggacccgct 2950

 cctaaggctg ctgtcaacac aggctgagga atctcaaggc ccagtgctca 3000

 agatgcctag ccagcgagca cggagcttcc ccctgaccag gtcccagtcc 3050

 tgtgagacga agctacttga cgaaaagacc agcaaactct attctatcag 3100

 cagccaagtg tcatcggctg tcatgaaatc cttgctgtgc cttccatctt 3150

 ctatctcctg tgcccagact ccctgcatcc ccaaggaagg ggcatctcca 3200

 acatcatcat ccaacgaaga ctcagctgca aatggttctg ctgaaacatc 3250

 tgccttggac acggggttct cgctcaacct ttcagagctg agagaatata 3300

 cagagggtct cacggaagcc aaggaagacg atgatgggga ccacagttcc 3350

 cttcagtctg gtcagtccgt tatctccctg ctgagctcag aagaattaaa 3400

 aaaactcatc gaggaggtga aggttctgga tgaagcaaca ttaaagcaat 3450

 tagacggcat ccatgtcacc atcttacaca aggaggaagg tgctggtctt 3500

 gggttcagct tggcaggagg agcagatcta gaaaacaagg tgattacggt 3550

 tcacagagtg tttccaaatg ggctggcctc ccaggaaggg actattcaga 3600

 agggcaatga ggttctttcc atcaacggca agtctctcaa ggggaccacg 3650

 caccatgatg ccttggccat cctccgccaa gctcgagagc ccaggcaagc 3700

 tgtgattgtc acaaggaagc tgactccaga ggccatgccc gacctcaact 3750

 cctccactga ctctgcagcc tcagcctctg cagccagtga tgtttctgta 3800

 gaatctacag cagaggccac agtctgcacg gtgacactgg agaagatgtc 3850

 ggcagggctg ggcttcagcc tggaaggagg gaagggctcc ctacacggag 3900

 acaagcctct caccattaac aggattttca aaggtggaca cagaggactt 3950

 cgtgccagag gcaagatccc tgtaaatatt gttgcacaaa aatctcacta 4000

 gctctcttcc cataccaccc aatgctgatg tcctcaccac atgcggagaa 4050

 caaatgtgaa gggagtagga tattgggtca gtgtccaaag cagggtctgg 4100

 gcaggactca gctccccaga gtcctctatg aactatggac ggtgctccag 4150

 gcaggctaag gcgtggagct gcctgatatt tccctcccct ggggacagca 4200

 agggctatcc ctttccaaag gccatggaga gctggagcct ggtgccctaa 4250

 cctctgagtc accatcttaa gagatgcctc attttagaac caccaacaag 4300

 caagctccca agggatggtg ccctgttctc taccaagcta tcctggctct 4350

 ttggagatca aggagaggag gcaactttcc ttgttcccca tcatctgtgg 4400

 aacccattac cttctccctc atttcaggag cagcctcaga acaaagtgag 4450

 acagtccagc ctggagatga aatcttgcag ctgggtggca ctgccatgca 4500

 gggcctcaca cggtttgaag cctggaacat catcaaggca ctgcctgatg 4550

 gacctgtcac gattgtcatc aggagaaaaa gcctccagtc caaggaaacc 4600

 acagctgctg gagactccta ggcaggacat gctgaagcca aagccaataa 4650

 cacacagcta acacacagct cccataaccg ctgattctca gggtctctgc 4700

 tgccgcccca cccagatggg ggaaagcaca ggtgggcttc ccagtggctg 4750

 ctgcccaggc ccagaccttc taggacgcca cccagcaaaa ggttgttcct 4800

 aaaataaggg cagagtcaca cgggggcagc tgatacaaat tgcagactgt 4850

 gtaaaaagag agcttaatga taatattgtg gtgccacaaa taaaatggat 4900

 ttattagaat ttcatatgac attcatgcct ggcttcgcaa aatgtttcaa 4950

 gtactgtaac tgtgtcatga ttcaccccca aacagtgaca tttatttttc 5000

 tcatgaatct gcaatgtggg cagagattgg aatgggcagc tcatctctgt 5050

 cccacttggc atcagctggc gtcatgcaaa gtcatgcaaa ggctgggacc 5100

 acgtgagatc attcactcat acatctggcc gttgatgttg gctgggaact 5150

 cacctggggc tgctggcctg aatgcttata ggtggcctct ccttgtggcc 5200

 tgggcctcct cacaacatgg tgtctggatt cccaggatga gcatcccagg 5250

 atcgcaagag ccatgtagaa gctgcatctt gtttatacct ttgccttgga 5300

 agttgcatgg catcacctcc accatactcc atcagttaga gctgacacaa 5350

 acctgcctgg gtttaagggg agaggaaata ttgctggggt catttatgaa 5400

 aaatacagtt tgtcacatga aacatttgca aaattgtttt tggttggatt 5450

 ggagaagtaa tcctagggaa gggtggtgga gccagtaaac agaggagtac 5500

 aggtgaagca ccaagctcaa agcgtggaca ggtgtgccga cagaaggaac 5550

 cagcgtgtat atgagggtat caaataaaat tgctactact tacctaccac 5600

 atgccaagca ctgtgctcag ggctaaacgg gcattgcctt tagtgatcac 5650

 agcagcttct acggtgtatg gttctgtgcc aatgtattga taagagggca 5700

 cacactgtgt acagtaaatg gcttatccag ctggtgagtg atgcggcaga 5750

 ttgagttttc ttctgtgatt cggtggagac tatcagccca agatgcttta 5800

 agtgcacaac attacaggga atgcctgagt gcctggccaa agggatattt 5850

 ggtttggcca tctctggatg cctgattgcc aagctcagga ccaggcaatg 5900

 tgactttgca tcagcaacaa ccagcatccc ttgaccaggc ctgggccaga 5950

 gtattggtct cctctcagcc cctgatcctg tgaagtaagg atgtggggga 6000

 agacctggca aggacacaga tgaaacacaa acaatagtaa ttctcaggcc 6050

 atcatcagtg gagccatgtt aatgtaatct gatggcttct ccagggtcca 6100

 caggaagtga agaatctgtt tcccagcagt ggactcaaaa cccatctggg 6150

 ctcctaacct tcctgtaaac ccctttagtg gcttcattag agcaggcgtt 6200

 cagctcactg ttctattcat ctcaaggaat aatgggctta gagcagtttc 6250

 tgtcctgctg gttaacttgt ttggcctatt ccattctgga ttttgtcaag 6300

 cagtagacaa gcaattagac aagaacttgg aggcaccatt tgtatccact 6350

 ttttagactt aatagaaaca ttgaagatga acataatcta ccaacgaaag 6400

 acgtgattca attcaacact cccttcccat gacccaggct gggcaaggag 6450

 gccacgtgat gtggagggca cattccttgc ctgcacaaac tcaccatctg 6500

 tgcacgcagt ggccttccct aaaatcaggg aattgtttta agtcttatca 6550

 agcagccaag ggatgaaaga gaaggtgggt tttcatcaag actggaaggt 6600

 ggggacaggg atgagcatgg agctggccgt gggcctgggg taccaagaga 6650

 ctccttgaga gaccaggcaa agcaagtgat tgggacagag gttatctgtc 6700

 ccaggttatc tgggcataga tgcaggtgag cccatggccc tcccagtacc 6750

 tcctgtctct ggcctgtttt agaaggttct ctcctcccca aggagacaca 6800

 acaactccta gggccactga agatataact attgcccagg tttctggtct 6850

 ctaggctggg gaagtcctct gggtaggaat cagcaagaag atcctaaaac 6900

 aaaagctcat ccatttgcgt tccatgatgc tgggatttac acttgaggct 6950

 tagctttgct ctgccaactt cttcagagct gacacaggat gaaggcaatg 7000

 ccatcctcaa acactgcagg catcacagct aacaattgtg aagtcgtctt 7050

 aactcaccat aaaaaggaat ccactcccag gcagccctac ttctttgctt 7100

 tgcccagcat tttactgatt catacattat ctcacttgtg ccaacactca 7150

 agaagcaggc tacactgaca ctggtattcc tgcctccata ttttctttaa 7200

 aagacaaatc aaagcagata tattaagtga ctgttcaaga gcacacttgg 7250

 cccaagtggc agagcttgga ctggatgcat gttttccagc tcctcatcca 7300

 gggctctgac cagtttaacc tgatgcagtc acgtggagga gcagtgcagg 7350

 cacagtatgt cccataggcc cagtgagatg cattcttggt tggctggcct 7400

 tccacttggc tacacaggga tgtacaaggc gatcccatct tgataagacc 7450

 accacctcag agtatggagc tcagagaggg caggcatgaa gtttccttgg 7500

 ctggtgcacc tagaattggc tgaactcatg agaagttgat atagaacagt 7550

 gcttgccaca gagcggggac tcggtaagca cttaatgaat gaatgaattc 7600

 taagtcaatc caagagtctg atgatttctt gaaaagggtg ttagctaaag 7650

 gatcttaggc atgactgtag aatttgtagt tgcaatagaa cagagaaaga 7700

 ggaagctttc tgtctcctta acactgagct gtcatgtttt aaagcttgct 7750

 cacatcttgg cacatttaag agacagtcac cccaggactc aaaaataggg 7800

 aagtaacagt aacgcagggg aaacgttttc tgtttggagg agcaaaggct 7850

 gagaacactg tgaaaacatt ttgcgcgcac aatagtaacc tgggtaaatg 7900

 cagcgtgaag ggattttagt cacacgtggt ctttcttaca aggaaggtgg 7950

 tgggggtgca gatgaggttg ctagagaatg ttagaggatc cctctctgga 8000

 ttggagatag ggaaagaaag ttgcacggct gctgaggccc cttctaggtg 8050

 gcaaggctgt gctccctggt tctgatgatg tgcctgggtg gacatggccc 8100

 ctgtgagttt gtacagtctt gcagcaggat ctagaggggg gatttccagc 8150

 cagggctgct agacggaggc ctactcttcc atctttcctg atggcaggat 8200

 ggcctggcca gggcctggaa gacagagacc tcctgcctcc gcctcagtaa 8250

 gacgacaagg aaaggcaaat gcccaaggga aagaaaagga aggctcttct 8300

 ccccagagtt ccccatgcag acatgagtgc gtgctcagtt cagaatcact 8350

 tctgagaact catccctaat gctgcagatt tgggctggaa cagattcaca 8400

 ctgtctggtt tcaccgagga catgaaactc caccttgcgg ggataaagag 8450

 agaaaaacaa attcatcaaa tggaagacac attgaaagtg tttttcctta 8500

 atgcttatcc tgtttttaaa ccattatttc caagttgaca ccttttttaa 8550

 ggaaaaataa atattttgcg gcattaaagc cataaaaaaa aaaaaaaaaa 8600

 aaaaaaaaaa aaaaa 8615

<210> 5620
<211> 1244
<212> PRT
<213> Homo sapien

<400> 5620
 Met Glu Ser His Ser Arg Ala Gly Lys Ser Arg Lys Ser Ala Lys
   1               5                  10                  15

 Phe Arg Ser Ile Ser Arg Ser Leu Met Leu Cys Asn Ala Lys Thr
                  20                  25                  30

 Ser Asp Asp Gly Ser Ser Pro Asp Glu Lys Tyr Pro Asp Pro Phe
                  35                  40                  45

 Glu Ile Ser Leu Ala Gln Gly Lys Glu Gly Ile Phe His Ser Ser
                  50                  55                  60

 Val Gln Leu Ala Asp Thr Ser Glu Ala Gly Pro Ser Ser Val Pro
                  65                  70                  75

 Asp Leu Ala Leu Ala Ser Glu Ala Ala Gln Leu Gln Ala Ala Gly
                  80                  85                  90

 Asn Asp Arg Gly Lys Thr Cys Arg Arg Ile Phe Phe Met Lys Glu
                  95                 100                 105

 Ser Ser Thr Ala Ser Ser Arg Glu Lys Pro Gly Lys Leu Glu Ala
                 110                 115                 120

 Gln Ser Ser Asn Phe Leu Phe Pro Lys Ala Cys His Gln Arg Ala
                 125                 130                 135

 Arg Ser Asn Ser Thr Ser Val Asn Pro Tyr Cys Thr Arg Glu Ile
                 140                 145                 150

 Asp Phe Pro Met Thr Lys Lys Ser Ala Ala Pro Thr Asp Arg Gln
                 155                 160                 165

 Pro Tyr Ser Leu Cys Ser Asn Arg Lys Ser Leu Ser Gln Gln Leu
                 170                 175                 180

 Asp Cys Pro Ala Gly Lys Ala Ala Gly Thr Ser Arg Pro Thr Arg
                 185                 190                 195

 Ser Leu Ser Thr Ala Gln Leu Val Gln Pro Ser Gly Gly Leu Gln
                 200                 205                 210

 Ala Ser Val Ile Ser Asn Ile Val Leu Met Lys Gly Gln Ala Lys
                 215                 220                 225

 Gly Leu Gly Phe Ser Ile Val Gly Gly Lys Asp Ser Ile Tyr Gly
                 230                 235                 240

 Pro Ile Gly Ile Tyr Val Lys Thr Ile Phe Ala Gly Gly Ala Ala
                 245                 250                 255

 Ala Ala Asp Gly Arg Leu Gln Glu Gly Asp Glu Ile Leu Glu Leu
                 260                 265                 270

 Asn Gly Glu Ser Met Ala Gly Leu Thr His Gln Asp Ala Leu Gln
                 275                 280                 285

 Lys Phe Lys Gln Ala Lys Lys Gly Leu Leu Thr Leu Thr Val Arg
                 290                 295                 300

 Thr Arg Leu Thr Ala Pro Pro Ser Leu Cys Ser His Leu Ser Pro
                 305                 310                 315

 Pro Leu Cys Arg Ser Leu Ser Ser Ser Thr Cys Ile Thr Lys Asp
                 320                 325                 330

 Ser Ser Ser Phe Ala Leu Glu Ser Pro Ser Ala Pro Ile Ser Thr
                 335                 340                 345

 Ala Lys Pro Asn Tyr Arg Ile Met Val Glu Val Ser Leu Gln Lys
                 350                 355                 360

 Glu Ala Gly Val Gly Leu Gly Ile Gly Leu Cys Ser Val Pro Tyr
                 365                 370                 375

 Phe Gln Cys Ile Ser Gly Ile Phe Val His Thr Leu Ser Pro Gly
                 380                 385                 390

 Ser Val Ala His Leu Asp Gly Arg Leu Arg Cys Gly Asp Glu Ile
                 395                 400                 405

 Val Glu Ile Ser Asp Ser Pro Val His Cys Leu Thr Leu Asn Glu
                 410                 415                 420

 Val Tyr Thr Ile Leu Ser His Cys Asp Pro Gly Pro Val Pro Ile
                 425                 430                 435

 Ile Val Ser Arg His Pro Asp Pro Gln Val Ser Glu Gln Gln Leu
                 440                 445                 450

 Lys Glu Ala Val Ala Gln Ala Val Glu Asn Thr Lys Phe Gly Lys
                 455                 460                 465

 Glu Arg His Gln Trp Ser Leu Glu Gly Val Lys Arg Leu Glu Ser
                 470                 475                 480

 Ser Trp His Gly Arg Pro Thr Leu Glu Lys Glu Arg Glu Lys Asn
                 485                 490                 495

 Ser Ala Pro Pro His Arg Arg Ala Gln Lys Val Met Ile Arg Ser
                 500                 505                 510

 Ser Ser Asp Ser Ser Tyr Met Ser Gly Ser Pro Gly Gly Ser Pro
                 515                 520                 525

 Gly Ser Gly Ser Ala Glu Lys Pro Ser Ser Asp Val Asp Ile Ser
                 530                 535                 540

 Thr His Ser Pro Ser Leu Pro Leu Ala Arg Glu Pro Val Val Leu
                 545                 550                 555

 Ser Ile Ala Ser Ser Arg Leu Pro Gln Glu Ser Pro Pro Leu Pro
                 560                 565                 570

 Glu Ser Arg Asp Ser His Pro Pro Leu Arg Leu Lys Lys Ser Phe
                 575                 580                 585

 Glu Ile Leu Glu Ala Arg Glu Leu Leu Pro Leu Leu Leu Pro Gln
                 590                 595                 600

 Glu Asp Thr Ala Gly Arg Ser Pro Ser Ala Ser Ala Gly Cys Pro
                 605                 610                 615

 Gly Pro Gly Ile Gly Pro Gln Thr Lys Ser Ser Thr Glu Gly Glu
                 620                 625                 630

 Pro Gly Trp Arg Arg Ala Ser Pro Val Thr Gln Thr Ser Pro Ile
                 635                 640                 645

 Lys His Pro Leu Leu Lys Arg Gln Ala Arg Met Asp Tyr Ser Phe
                 650                 655                 660

 Asp Thr Thr Ala Glu Asp Pro Trp Val Arg Ile Ser Asp Cys Ile
                 665                 670                 675

 Lys Asn Leu Phe Ser Pro Ile Met Ser Glu Asn His Gly His Met
                 680                 685                 690

 Pro Leu Gln Pro Asn Ala Ser Leu Asn Glu Glu Glu Gly Thr Gln
                 695                 700                 705

 Gly His Pro Asp Gly Thr Pro Pro Lys Leu Asp Thr Ala Asn Gly
                 710                 715                 720

 Thr Pro Lys Val Tyr Lys Ser Ala Asp Ser Ser Thr Val Lys Lys
                 725                 730                 735

 Gly Pro Pro Val Ala Pro Lys Pro Ala Trp Phe Arg Gln Ser Leu
                 740                 745                 750

 Lys Gly Leu Arg Asn Arg Ala Ser Asp Pro Arg Gly Leu Pro Asp
                 755                 760                 765

 Pro Ala Leu Ser Thr Gln Pro Ala Pro Ala Ser Arg Glu His Leu
                 770                 775                 780

 Gly Ser His Ile Arg Ala Ser Ser Ser Ser Ser Ser Ile Arg Gln
                 785                 790                 795

 Arg Ile Ser Ser Phe Glu Thr Phe Gly Ser Ser Gln Leu Pro Asp
                 800                 805                 810

 Lys Gly Ala Gln Arg Leu Ser Leu Gln Pro Ser Ser Gly Glu Ala
                 815                 820                 825

 Ala Lys Pro Leu Gly Lys His Glu Glu Gly Arg Phe Ser Gly Leu
                 830                 835                 840

 Leu Gly Arg Gly Ala Ala Pro Thr Leu Val Pro Gln Gln Pro Glu
                 845                 850                 855

 Gln Val Leu Ser Ser Gly Ser Pro Ala Ala Ser Glu Ala Arg Asp
                 860                 865                 870

 Pro Gly Val Ser Glu Ser Pro Pro Pro Gly Arg Gln Pro Asn Gln
                 875                 880                 885

 Lys Thr Leu Pro Pro Gly Pro Asp Pro Leu Leu Arg Leu Leu Ser
                 890                 895                 900

 Thr Gln Ala Glu Glu Ser Gln Gly Pro Val Leu Lys Met Pro Ser
                 905                 910                 915

 Gln Arg Ala Arg Ser Phe Pro Leu Thr Arg Ser Gln Ser Cys Glu
                 920                 925                 930

 Thr Lys Leu Leu Asp Glu Lys Thr Ser Lys Leu Tyr Ser Ile Ser
                 935                 940                 945

 Ser Gln Val Ser Ser Ala Val Met Lys Ser Leu Leu Cys Leu Pro
                 950                 955                 960

 Ser Ser Ile Ser Cys Ala Gln Thr Pro Cys Ile Pro Lys Glu Gly
                 965                 970                 975

 Ala Ser Pro Thr Ser Ser Ser Asn Glu Asp Ser Ala Ala Asn Gly
                 980                 985                 990

 Ser Ala Glu Thr Ser Ala Leu Asp Thr Gly Phe Ser Leu Asn Leu
                 995                1000                1005

 Ser Glu Leu Arg Glu Tyr Thr Glu Gly Leu Thr Glu Ala Lys Glu
                1010                1015                1020

 Asp Asp Asp Gly Asp His Ser Ser Leu Gln Ser Gly Gln Ser Val
                1025                1030                1035

 Ile Ser Leu Leu Ser Ser Glu Glu Leu Lys Lys Leu Ile Glu Glu
                1040                1045                1050

 Val Lys Val Leu Asp Glu Ala Thr Leu Lys Gln Leu Asp Gly Ile
                1055                1060                1065

 His Val Thr Ile Leu His Lys Glu Glu Gly Ala Gly Leu Gly Phe
                1070                1075                1080

 Ser Leu Ala Gly Gly Ala Asp Leu Glu Asn Lys Val Ile Thr Val
                1085                1090                1095

 His Arg Val Phe Pro Asn Gly Leu Ala Ser Gln Glu Gly Thr Ile
                1100                1105                1110

 Gln Lys Gly Asn Glu Val Leu Ser Ile Asn Gly Lys Ser Leu Lys
                1115                1120                1125

 Gly Thr Thr His His Asp Ala Leu Ala Ile Leu Arg Gln Ala Arg
                1130                1135                1140

 Glu Pro Arg Gln Ala Val Ile Val Thr Arg Lys Leu Thr Pro Glu
                1145                1150                1155

 Ala Met Pro Asp Leu Asn Ser Ser Thr Asp Ser Ala Ala Ser Ala
                1160                1165                1170

 Ser Ala Ala Ser Asp Val Ser Val Glu Ser Thr Ala Glu Ala Thr
                1175                1180                1185

 Val Cys Thr Val Thr Leu Glu Lys Met Ser Ala Gly Leu Gly Phe
                1190                1195                1200

 Ser Leu Glu Gly Gly Lys Gly Ser Leu His Gly Asp Lys Pro Leu
                1205                1210                1215

 Thr Ile Asn Arg Ile Phe Lys Gly Gly His Arg Gly Leu Arg Ala
                1220                1225                1230

 Arg Gly Lys Ile Pro Val Asn Ile Val Ala Gln Lys Ser His
                1235                1240

<210> 5621
<211> 1061
<212> DNA
<213> Homo sapien

<400> 5621
 agacaaaaag taaccttcct gaagaggaca tgtgattgga agttgtcaat 50

 tgttgaagca ttggtaactc cagtctctaa cgttttagaa aatcataaca 100

 agcggttctg taccctgtaa agaacagaaa cctggaaatc taaggctcaa 150

 agacatccaa gtaattggta tctgggagat ttgggattca aacccagctc 200

 tgcttgactt ggtgaactac tgagttcttc attatgtctg atggagatta 250

 tgattacctc atcaagtttt tagctttggg agactctggt gtagggaaga 300

 ccagtgtact ttaccaatat acagatggta aatttaactc caaatttatc 350

 acaacagtgg gcattgattt caggccaaaa agagtggtgt acagagccag 400

 tgggccggat ggaccagtag gtagaggcca gagaatccac ctgcagttat 450

 gggacacagc agggcaggag aggtttcgta gcttaacgac agcgttcttc 500

 agagatgcta tgggttttct tctacttttt gatctgacaa atgagcaaag 550

 tttcctcaat gtcagaaact ggataagcca gctacagatg catgcatatt 600

 gtgaaaaccc agatatagtg ctgtgtggaa acaagagtga tctggaggac 650

 cagagagtag tgaaagagga ggaagccata gcactcgcag agaaatatgg 700

 aatcccctac tttgaaacta gtgctgccaa tgggacaaac ataagccaag 750

 caattgagat gcttctggac ctgataatga agcgaatgga acggtgtgtg 800

 gacaagtcct ggattcctga aggagtggtg cgatcaaatg gtcatgcctc 850

 tacggatcag ttaagtgaag aaaaggagaa aggggcatgt ggctgttgag 900

 aagtcaagta acgacatagt agttcaggtg gcccatgcct gggatcttct 950

 ctatgattga tacatggcac agtgagagat taatgggcat tgtgtacaaa 1000

 ttgcttctca ccatccccat tagacctacg aataaagcat ccggttctaa 1050

 aattaaaaaa a 1061

<210> 5622
<211> 221
<212> PRT
<213> Homo sapien

<400> 5622
 Met Ser Asp Gly Asp Tyr Asp Tyr Leu Ile Lys Phe Leu Ala Leu
   1               5                  10                  15

 Gly Asp Ser Gly Val Gly Lys Thr Ser Val Leu Tyr Gln Tyr Thr
                  20                  25                  30

 Asp Gly Lys Phe Asn Ser Lys Phe Ile Thr Thr Val Gly Ile Asp
                  35                  40                  45

 Phe Arg Pro Lys Arg Val Val Tyr Arg Ala Ser Gly Pro Asp Gly
                  50                  55                  60

 Pro Val Gly Arg Gly Gln Arg Ile His Leu Gln Leu Trp Asp Thr
                  65                  70                  75

 Ala Gly Gln Glu Arg Phe Arg Ser Leu Thr Thr Ala Phe Phe Arg
                  80                  85                  90

 Asp Ala Met Gly Phe Leu Leu Leu Phe Asp Leu Thr Asn Glu Gln
                  95                 100                 105

 Ser Phe Leu Asn Val Arg Asn Trp Ile Ser Gln Leu Gln Met His
                 110                 115                 120

 Ala Tyr Cys Glu Asn Pro Asp Ile Val Leu Cys Gly Asn Lys Ser
                 125                 130                 135

 Asp Leu Glu Asp Gln Arg Val Val Lys Glu Glu Glu Ala Ile Ala
                 140                 145                 150

 Leu Ala Glu Lys Tyr Gly Ile Pro Tyr Phe Glu Thr Ser Ala Ala
                 155                 160                 165

 Asn Gly Thr Asn Ile Ser Gln Ala Ile Glu Met Leu Leu Asp Leu
                 170                 175                 180

 Ile Met Lys Arg Met Glu Arg Cys Val Asp Lys Ser Trp Ile Pro
                 185                 190                 195

 Glu Gly Val Val Arg Ser Asn Gly His Ala Ser Thr Asp Gln Leu
                 200                 205                 210

 Ser Glu Glu Lys Glu Lys Gly Ala Cys Gly Cys
                 215                 220

<210> 5623
<211> 768
<212> DNA
<213> Homo sapien

<400> 5623
 ccttcagcat aaaagctgat ccacaaacaa gaggagcacc agacctcctc 50

 ttggcttcga gatggcttcg ccacaccaag agcccaaacc tggagacctg 100

 attgagattt tccgccttgg ctatgagcac tgggccctgt atataggaga 150

 tggctacgtg atccatctgg ctcctccaag tgagtacccc ggggctggct 200

 cctccagtgt cttctcagtc ctgagcaaca gtgcagaggt gaaacggggg 250

 cgcctggaag atgtggtggg aggctgttgc tatcgggtca acaacagctt 300

 ggaccatgag taccaaccac ggcccgtgga ggtgatcatc agttctgcga 350

 aggagatggt tggtcagaag atgaagtaca gtattgtgag caggaactgt 400

 gagcactttg tcgcccagct gagatatggc aagtcccgct gtaaacaggt 450

 ggaaaaggcc aaggttgaag tcggtgtggc cacggcgctt ggaatcctgg 500

 ttgttgctgg atgctctttt gcgattagga gataccaaaa aaaagcaaca 550

 gcctgaagca gccacaaaat cctgtgttag aagcagctgt gggggtccca 600

 gtggagatga gcctccccca tgcctccagc agcctgaccc tcgtgccctg 650

 tctcaggcgt tctctagatc ctttcctctg tttccctctc tcgctggcaa 700

 aagtatgatc taattgaaac aagactgaag gatcaataaa cagccatctg 750

 ccccttcaaa aaaaaaaa 768

<210> 5624
<211> 164
<212> PRT
<213> Homo sapien

<400> 5624
 Met Ala Ser Pro His Gln Glu Pro Lys Pro Gly Asp Leu Ile Glu
   1               5                  10                  15

 Ile Phe Arg Leu Gly Tyr Glu His Trp Ala Leu Tyr Ile Gly Asp
                  20                  25                  30

 Gly Tyr Val Ile His Leu Ala Pro Pro Ser Glu Tyr Pro Gly Ala
                  35                  40                  45

 Gly Ser Ser Ser Val Phe Ser Val Leu Ser Asn Ser Ala Glu Val
                  50                  55                  60

 Lys Arg Gly Arg Leu Glu Asp Val Val Gly Gly Cys Cys Tyr Arg
                  65                  70                  75

 Val Asn Asn Ser Leu Asp His Glu Tyr Gln Pro Arg Pro Val Glu
                  80                  85                  90

 Val Ile Ile Ser Ser Ala Lys Glu Met Val Gly Gln Lys Met Lys
                  95                 100                 105

 Tyr Ser Ile Val Ser Arg Asn Cys Glu His Phe Val Ala Gln Leu
                 110                 115                 120

 Arg Tyr Gly Lys Ser Arg Cys Lys Gln Val Glu Lys Ala Lys Val
                 125                 130                 135

 Glu Val Gly Val Ala Thr Ala Leu Gly Ile Leu Val Val Ala Gly
                 140                 145                 150

 Cys Ser Phe Ala Ile Arg Arg Tyr Gln Lys Lys Ala Thr Ala
                 155                 160

<210> 5625
<211> 4097
<212> DNA
<213> Homo sapien

<400> 5625
 gctggcggcg gccgcccagg gccggggccg cgcgcccagc ctgagcccgc 50

 cccgccgccg agcgtcaccg aacctgcttg aaatgcagcc gaggagccgg 100

 ggcgggcggc agcggcggcg gcggcggcgg cgggggcagc ggcaaccccg 150

 gcgccgcggc aaggactcgg agggctgaga cgcggcggcg gcggcgcggg 200

 gagcgcgggg cgcggcggcc ggagcccggg cccgccatgg gcctccccga 250

 gccgggccct ctccggcttc tggcgctgct gctgctgctg ctgctgctgc 300

 tgctgctgcg gctccagcat cttgcggcgg cagcggctga tccgctgctc 350

 ggcggccaag ggccggccaa ggagtgcgaa aaggaccaat tccagtgccg 400

 gaacgagcgc tgcatcccct ctgtgtggag atgcgacgag gacgatgact 450

 gcttagacca cagcgacgag gacgactgcc ccaagaagac ctgtgcagac 500

 agtgacttca cctgtgacaa cggccactgc atccacgaac ggtggaagtg 550

 tgacggcgag gaggagtgtc ctgatggctc cgatgagtcc gaggccactt 600

 gcaccaagca ggtgtgtcct gcagagaagc tgagctgtgg acccaccagc 650

 cacaagtgtg tacctgcctc gtggcgctgc gacggggaga aggactgcga 700

 gggtggagcg gatgaggccg gctgtgctac ctggctgaac gagtgtctgc 750

 acaacaatgg cggctgctca cacatctgca ctgacctcaa gattggcttt 800

 gaatgcacgt gcccagcagg cttccagctc ctggaccaga agacctgtgg 850

 cgacattgat gagtgcaagg acccagatgc ctgcagccag atctgtgtca 900

 attacaaggg ctattttaag tgtgagtgct accctggcta cgagatggac 950

 ctactgacca agaactgcaa ggctgctggt ggaaagagcc catccctaat 1000

 cttcaccaac cggtacgagg tgcggaggat cgacctggtg aagcggaact 1050

 attcacgcct catccccatg ctcaagaatg tcgtggcact agatgtggaa 1100

 gttgccacca atcgcatcta ctggtgtgac ctctcctacc gtaagatcta 1150

 tagcgcctac atggacaagg ccagtgaccc gaaagagcag gaggtcctca 1200

 ttgacgagca gttgcactct ccagagggcc tggcagtgga ctgggtccac 1250

 aagcacatct actggactga ctcgggcaat aagaccatct cagtggccac 1300

 agttgatggt ggccgccgac gcactctctt cagccgtaac ctcagtgaac 1350

 cccgggccat cgctgttgac cccctgcgag ggttcatgta ttggtctgac 1400

 tggggggacc aggccaagat tgagaaatct gggctcaacg gtgtggaccg 1450

 gcaaacactg gtgtcagaca atattgaatg gcccaacgga atcaccctgg 1500

 atctgctgag ccagcgcttg tactgggtag actccaagct acaccaactg 1550

 tccagcattg acttcagtgg aggcaacaga aagacgctga tctcctccac 1600

 tgacttcctg agccaccctt ttgggatagc tgtgtttgag gacaaggtgt 1650

 tctggacaga cctggagaac gaggccattt tcagtgcaaa tcggctcaat 1700

 ggcctggaaa tctccatcct ggctgagaac ctcaacaacc cacatgacat 1750

 tgtcatcttc catgagctga agcagccaag agctccagat gcctgtgagc 1800

 tgagtgtcca gcctaatgga ggctgtgaat acctgtgcct tcctgctcct 1850

 cagatctcca gccactctcc caagtacaca tgtgcctgtc ctgacacaat 1900

 gtggctgggt ccagacatga agaggtgcta ccgagcacct caatctacct 1950

 caactacgac gttagcttct accatgacga ggacagtacc tgccaccaca 2000

 agagcccccg ggaccaccgt ccacagatcc acctaccaga accacagcac 2050

 agagacacca agcctgacag ctgcagtccc aagctcagtt agtgtcccca 2100

 gggctcccag catcagcccg tctaccctaa gccctgcaac cagcaaccac 2150

 tcccagcact atgcaaatga agacagtaag atgggctcaa cagtcactgc 2200

 cgctgttatc gggatcatcg tgcccatagt ggtgatagcc ctcctgtgca 2250

 tgagtggata cctgatctgg agaaactgga agcggaagaa caccaaaagc 2300

 atgaattttg acaacccagt ctacaggaaa acaacagaag aagaagatga 2350

 agatgagctc catataggga gaactgctca gattggccat gtctatcctg 2400

 cagcaatcag cagctttgat cgcccactgt gggcagagcc ctgtcttggg 2450

 gagaccagag aaccggaaga cccagcccct gccctcaagg agctttttgt 2500

 cttgccgggg gaaccaaggt cacagctgca ccaactcccg aagaaccctc 2550

 tttccgagct gcctgtcgtc aaatccaagc gagtggcatt aagccttgaa 2600

 gatgatggac taccctgagg atgggatcac ccccttcgtg cctcatggaa 2650

 ttcagtccca tgcactacac tctggatggt gtatgactgg atgaatgggt 2700

 ttctatatat gggtctgtgt gagtgtatgt gtgtgtgtga tttttttttt 2750

 aaatttatgt tgcggaaagg taaccacaaa gttatgatga actgcaaaca 2800

 tccaaaggat gtgagagttt ttctatgtat aatgttttat acacttttta 2850

 actggttgca ctacccatga ggaattcgtg gaatggctac tgctgactaa 2900

 catgatgcac ataaccaaat gggggccaat ggcacagtac cttactcatc 2950

 atttaaaaac tatatttaca gaagatgttt ggttgctggg ggggcttttt 3000

 tgggttttgg ggcatttgtt ttttgtaaat aagatgatta tgctttgtgg 3050

 ctatccatca acataagtaa aaaaaaaaaa aaaacacttc aactccctcc 3100

 cccatttaga ttatttatta acatatttta aaaatcagat gagttctata 3150

 aataatttag agaagtgaga gtatttattt ttggcatgtt tggcccacca 3200

 cacagactct gtgtgtgtat gtgtgtgttt atatgtgtat gtgtgtgaca 3250

 ggaaaatctg tagagaagag gcacatctat ggctactgtt caaatacata 3300

 aagataaatt tattttcaca cagtccacaa ggggtatatc ttgtagtttt 3350

 cagaaaagcc tttggaaatc tggatcagga aatagatacc atggtttgtg 3400

 caattatgta gtaaaaaagg caaatctttt cacctctggc tattcctgag 3450

 accccaggaa gtcaggaaaa gcctttcagc tcacccatgg ctgctgtgac 3500

 tcctaccagg gctttcttgg ctttggcgaa ggtcagtgta cagacattcc 3550

 atggtaccag agtgctcaga aagtcaagat aggatatgcc tcaccctcag 3600

 ctactccttg ttttaaagtt cagctctttg agtaacttct tcaatttctt 3650

 tcaggacact tgggttgaat tcagtaagtt tcctctgaag caccctgaag 3700

 ggtgccatcc ttacagagct aagtggagac gtttccagat cagcccaagt 3750

 ttactataga gactggccca ggcactgaat gtctaggaca tgctgtggat 3800

 gaagataaag atggtggaat aggttttatc acatctctta tttctctttt 3850

 ccccttactc tctaccattt cctttatgtg gggaaacatt ttaaggtaat 3900

 aaataggtta cttaccatca tatgttcata tagatgaaac taatttttgg 3950

 cttaagtcag aacaactggc ccccaattga agtcatattt gtggggggaa 4000

 atggcatacg caatattata ttatattgga tatttatgtt cacacaggaa 4050

 tttggtttac tgctttgtaa ataaaaggga aaactccggg tatatgt 4097

<210> 5626
<211> 793
<212> PRT
<213> Homo sapien

<400> 5626
 Met Gly Leu Pro Glu Pro Gly Pro Leu Arg Leu Leu Ala Leu Leu
   1               5                  10                  15

 Leu Leu Leu Leu Leu Leu Leu Leu Leu Arg Leu Gln His Leu Ala
                  20                  25                  30

 Ala Ala Ala Ala Asp Pro Leu Leu Gly Gly Gln Gly Pro Ala Lys
                  35                  40                  45

 Glu Cys Glu Lys Asp Gln Phe Gln Cys Arg Asn Glu Arg Cys Ile
                  50                  55                  60

 Pro Ser Val Trp Arg Cys Asp Glu Asp Asp Asp Cys Leu Asp His
                  65                  70                  75

 Ser Asp Glu Asp Asp Cys Pro Lys Lys Thr Cys Ala Asp Ser Asp
                  80                  85                  90

 Phe Thr Cys Asp Asn Gly His Cys Ile His Glu Arg Trp Lys Cys
                  95                 100                 105

 Asp Gly Glu Glu Glu Cys Pro Asp Gly Ser Asp Glu Ser Glu Ala
                 110                 115                 120

 Thr Cys Thr Lys Gln Val Cys Pro Ala Glu Lys Leu Ser Cys Gly
                 125                 130                 135

 Pro Thr Ser His Lys Cys Val Pro Ala Ser Trp Arg Cys Asp Gly
                 140                 145                 150

 Glu Lys Asp Cys Glu Gly Gly Ala Asp Glu Ala Gly Cys Ala Thr
                 155                 160                 165

 Trp Leu Asn Glu Cys Leu His Asn Asn Gly Gly Cys Ser His Ile
                 170                 175                 180

 Cys Thr Asp Leu Lys Ile Gly Phe Glu Cys Thr Cys Pro Ala Gly
                 185                 190                 195

 Phe Gln Leu Leu Asp Gln Lys Thr Cys Gly Asp Ile Asp Glu Cys
                 200                 205                 210

 Lys Asp Pro Asp Ala Cys Ser Gln Ile Cys Val Asn Tyr Lys Gly
                 215                 220                 225

 Tyr Phe Lys Cys Glu Cys Tyr Pro Gly Tyr Glu Met Asp Leu Leu
                 230                 235                 240

 Thr Lys Asn Cys Lys Ala Ala Gly Gly Lys Ser Pro Ser Leu Ile
                 245                 250                 255

 Phe Thr Asn Arg Tyr Glu Val Arg Arg Ile Asp Leu Val Lys Arg
                 260                 265                 270

 Asn Tyr Ser Arg Leu Ile Pro Met Leu Lys Asn Val Val Ala Leu
                 275                 280                 285

 Asp Val Glu Val Ala Thr Asn Arg Ile Tyr Trp Cys Asp Leu Ser
                 290                 295                 300

 Tyr Arg Lys Ile Tyr Ser Ala Tyr Met Asp Lys Ala Ser Asp Pro
                 305                 310                 315

 Lys Glu Gln Glu Val Leu Ile Asp Glu Gln Leu His Ser Pro Glu
                 320                 325                 330

 Gly Leu Ala Val Asp Trp Val His Lys His Ile Tyr Trp Thr Asp
                 335                 340                 345

 Ser Gly Asn Lys Thr Ile Ser Val Ala Thr Val Asp Gly Gly Arg
                 350                 355                 360

 Arg Arg Thr Leu Phe Ser Arg Asn Leu Ser Glu Pro Arg Ala Ile
                 365                 370                 375

 Ala Val Asp Pro Leu Arg Gly Phe Met Tyr Trp Ser Asp Trp Gly
                 380                 385                 390

 Asp Gln Ala Lys Ile Glu Lys Ser Gly Leu Asn Gly Val Asp Arg
                 395                 400                 405

 Gln Thr Leu Val Ser Asp Asn Ile Glu Trp Pro Asn Gly Ile Thr
                 410                 415                 420

 Leu Asp Leu Leu Ser Gln Arg Leu Tyr Trp Val Asp Ser Lys Leu
                 425                 430                 435

 His Gln Leu Ser Ser Ile Asp Phe Ser Gly Gly Asn Arg Lys Thr
                 440                 445                 450

 Leu Ile Ser Ser Thr Asp Phe Leu Ser His Pro Phe Gly Ile Ala
                 455                 460                 465

 Val Phe Glu Asp Lys Val Phe Trp Thr Asp Leu Glu Asn Glu Ala
                 470                 475                 480

 Ile Phe Ser Ala Asn Arg Leu Asn Gly Leu Glu Ile Ser Ile Leu
                 485                 490                 495

 Ala Glu Asn Leu Asn Asn Pro His Asp Ile Val Ile Phe His Glu
                 500                 505                 510

 Leu Lys Gln Pro Arg Ala Pro Asp Ala Cys Glu Leu Ser Val Gln
                 515                 520                 525

 Pro Asn Gly Gly Cys Glu Tyr Leu Cys Leu Pro Ala Pro Gln Ile
                 530                 535                 540

 Ser Ser His Ser Pro Lys Tyr Thr Cys Ala Cys Pro Asp Thr Met
                 545                 550                 555

 Trp Leu Gly Pro Asp Met Lys Arg Cys Tyr Arg Ala Pro Gln Ser
                 560                 565                 570

 Thr Ser Thr Thr Thr Leu Ala Ser Thr Met Thr Arg Thr Val Pro
                 575                 580                 585

 Ala Thr Thr Arg Ala Pro Gly Thr Thr Val His Arg Ser Thr Tyr
                 590                 595                 600

 Gln Asn His Ser Thr Glu Thr Pro Ser Leu Thr Ala Ala Val Pro
                 605                 610                 615

 Ser Ser Val Ser Val Pro Arg Ala Pro Ser Ile Ser Pro Ser Thr
                 620                 625                 630

 Leu Ser Pro Ala Thr Ser Asn His Ser Gln His Tyr Ala Asn Glu
                 635                 640                 645

 Asp Ser Lys Met Gly Ser Thr Val Thr Ala Ala Val Ile Gly Ile
                 650                 655                 660

 Ile Val Pro Ile Val Val Ile Ala Leu Leu Cys Met Ser Gly Tyr
                 665                 670                 675

 Leu Ile Trp Arg Asn Trp Lys Arg Lys Asn Thr Lys Ser Met Asn
                 680                 685                 690

 Phe Asp Asn Pro Val Tyr Arg Lys Thr Thr Glu Glu Glu Asp Glu
                 695                 700                 705

 Asp Glu Leu His Ile Gly Arg Thr Ala Gln Ile Gly His Val Tyr
                 710                 715                 720

 Pro Ala Ala Ile Ser Ser Phe Asp Arg Pro Leu Trp Ala Glu Pro
                 725                 730                 735

 Cys Leu Gly Glu Thr Arg Glu Pro Glu Asp Pro Ala Pro Ala Leu
                 740                 745                 750

 Lys Glu Leu Phe Val Leu Pro Gly Glu Pro Arg Ser Gln Leu His
                 755                 760                 765

 Gln Leu Pro Lys Asn Pro Leu Ser Glu Leu Pro Val Val Lys Ser
                 770                 775                 780

 Lys Arg Val Ala Leu Ser Leu Glu Asp Asp Gly Leu Pro
                 785                 790

<210> 5627
<211> 2901
<212> DNA
<213> Homo sapien

<400> 5627
 cagcctccct ctcccacctc tgtctgcccg ctgcctcttg tctagctgct 50

 gtcaggagct gactgcctcc agggctggaa tcctgtgctc cctctgtgcc 100

 cagagcccca cgatgtcggc caacgccaca ctgaagccac tctgccccat 150

 cctggagcag atgagccgtc tccagagcca cagcaacacc agcatccgct 200

 acatcgacca cgcggccgtg ctgctgcacg ggctggcctc gctgctgggc 250

 ctggtggaga atggagtcat cctcttcgtg gtgggctgcc gcatgcgcca 300

 gaccgtggtc accacctggg tgctgcacct ggcgctgtcc gacctgttgg 350

 cctctgcttc cctgcccttc ttcacctact tcttggccgt gggccactcg 400

 tgggagctgg gcaccacctt ctgcaaactg cactcctcca tcttctttct 450

 caacatgttc gccagcggct tcctgctcag cgccatcagc ctggaccgct 500

 gcctgcaggt ggtgcggccg gtgtgggcgc agaaccaccg caccgtggcc 550

 gcggcgcaca aagtctgcct ggtgctttgg gcactagcgg tgctcaacac 600

 ggtgccctat ttcgtgttcc gggacaccat ctcgcggctg gacgggcgca 650

 ttatgtgcta ctacaatgtg ctgctcctga acccggggcc tgaccgcgat 700

 gccacgtgca actcgcgcca ggcggccctg gccgtcagca agttcctgct 750

 ggccttcctg gtgccgctgg cgatcatcgc ctcgagccac gcggccgtga 800

 gcctgcggtt gcagcaccgc ggccgccggc ggccaggccg cttcgtgcgc 850

 ctggtggcag ccgtcgtggc cgccttcgcg ctctgctggg ggccctacca 900

 cgtgttcagc ctgctggagg cgcgggcgca cgcaaacccg gggctgcggc 950

 cgctcgtgtg gcgcgggctg cccttcgtca ccagcctggc cttcttcaac 1000

 agcgtggcca acccggtgct ctacgtgctc acctgccccg acatgctgcg 1050

 caagctgcgg cgctcgctgc gcacggtgct ggagagcgtg ctggtggacg 1100

 acagcgagct gggtggcgcg ggaagcagcc gccgccgccg cacctcctcc 1150

 accgcccgct cggcctcccc tttagctctc tgcagccgcc cggaggaacc 1200

 gcggggcccc gcgcgtctcc tcggctggct gctgggcagc tgcgcagcgt 1250

 ccccgcagac gggccccctg aaccgggcgc tgagcagcac ctcgagttag 1300

 aacccggccc acgtagggcg gcactcacac gcgaaagtat caccagggtg 1350

 ccgcggttca attcgatatc cggactcctg ccgcagtgat caaagtccga 1400

 ggggcgggac ccaggcacct gcattttaaa gcgccccggg agactctgaa 1450

 tctttttcag aaacagtgag ttaaagcagt gcttctcaaa ccttgatgtg 1500

 cctgtgaatc acctaggggt cttgttaagt gcagtctgat ccaggaggcc 1550

 ggggccgggt actgagagtc tgcacttaac aagctcccag gccgagaagc 1600

 cagtgcggca ggttcacagg cgaggcctgg agtaacacaa agtgaaactc 1650

 gtaatagact tcccactcta gggcagtgga gtcggaaggg cacacggggt 1700

 gcgtctcccc ggagttcagt tttaccagat gatgggggag gggggaagga 1750

 gttttatgtt aaaccatcca tgtatttttg gagaagagag aggaaaggtt 1800

 tgagaagcac tgttccagcc tgccctcttc atttagccaa tgcttactgc 1850

 gctagacgct tcatcccaca atcttaaggg gcagcttcta ttagccagtc 1900

 tttacagctg agcacattct ggctcaggga ggttaagtga cttgcccagt 1950

 ttcagggcta acgaccacag ggtctgcact ctaaccctag gcatcacatg 2000

 ctcaatgact ctctggtgag cgaggacatt ctctgaccta ctcgagggac 2050

 ttaagatgct accttgtgac ccagcactgc ccaaagtgct tccaaggcag 2100

 aagcagcagg ggatggcgtg gtcaagcact cgggaaacct ggggctaatc 2150

 aaatccaatg ggggaaatga ctaaaagtct tcggtcgtta gaagttgaat 2200

 gggcacagca actctaagac tacagcacac gtcatttctt agctaagcgg 2250

 accagcctcc ctgtcggcct ggtgttctgt gggatccctc tgggcactgg 2300

 taatcccaag atctgtgcag ccccgcctcc aggccacatg gggctgggca 2350

 gctaccattt cccttttgcg gatgggaggg gtaacttgca cctctgacct 2400

 atcacttcca ctgcaccccg tctcattcct ccacctgccg tggacttggg 2450

 gtcagagact gctgtgtttg agctctgcag cccagggacc gaaaagttgg 2500

 tgtcaatgaa ttttgcttgg tggatgaaat gtcagtggaa gaagcagatg 2550

 agaaactctt gagatcttgg tcctgtgttt tttctgccac caaaggccag 2600

 ggtcactgaa ggcctggccc acagcaggtg ctgagcaaag ggaacagtga 2650

 ggtgcccagc tagctgcaga gccaccctgt gttgacacct cgcccctgct 2700

 ccctcccatc ccttccccct ttactcatag cacttccccc attggacacg 2750

 tggtgcattt tgcttgttta ttatgttttc tctccatcag aatgaaagct 2800

 cctcgagggc agggactttg gtctattgtc tgtatttgcc ggtgcctagg 2850

 attgtgcctg tatgcaacag gcactcaata aatatttttg ctgtagactg 2900

 g 2901

<210> 5628
<211> 395
<212> PRT
<213> Homo sapien

<400> 5628
 Met Ser Ala Asn Ala Thr Leu Lys Pro Leu Cys Pro Ile Leu Glu
   1               5                  10                  15

 Gln Met Ser Arg Leu Gln Ser His Ser Asn Thr Ser Ile Arg Tyr
                  20                  25                  30

 Ile Asp His Ala Ala Val Leu Leu His Gly Leu Ala Ser Leu Leu
                  35                  40                  45

 Gly Leu Val Glu Asn Gly Val Ile Leu Phe Val Val Gly Cys Arg
                  50                  55                  60

 Met Arg Gln Thr Val Val Thr Thr Trp Val Leu His Leu Ala Leu
                  65                  70                  75

 Ser Asp Leu Leu Ala Ser Ala Ser Leu Pro Phe Phe Thr Tyr Phe
                  80                  85                  90

 Leu Ala Val Gly His Ser Trp Glu Leu Gly Thr Thr Phe Cys Lys
                  95                 100                 105

 Leu His Ser Ser Ile Phe Phe Leu Asn Met Phe Ala Ser Gly Phe
                 110                 115                 120

 Leu Leu Ser Ala Ile Ser Leu Asp Arg Cys Leu Gln Val Val Arg
                 125                 130                 135

 Pro Val Trp Ala Gln Asn His Arg Thr Val Ala Ala Ala His Lys
                 140                 145                 150

 Val Cys Leu Val Leu Trp Ala Leu Ala Val Leu Asn Thr Val Pro
                 155                 160                 165

 Tyr Phe Val Phe Arg Asp Thr Ile Ser Arg Leu Asp Gly Arg Ile
                 170                 175                 180

 Met Cys Tyr Tyr Asn Val Leu Leu Leu Asn Pro Gly Pro Asp Arg
                 185                 190                 195

 Asp Ala Thr Cys Asn Ser Arg Gln Ala Ala Leu Ala Val Ser Lys
                 200                 205                 210

 Phe Leu Leu Ala Phe Leu Val Pro Leu Ala Ile Ile Ala Ser Ser
                 215                 220                 225

 His Ala Ala Val Ser Leu Arg Leu Gln His Arg Gly Arg Arg Arg
                 230                 235                 240

 Pro Gly Arg Phe Val Arg Leu Val Ala Ala Val Val Ala Ala Phe
                 245                 250                 255

 Ala Leu Cys Trp Gly Pro Tyr His Val Phe Ser Leu Leu Glu Ala
                 260                 265                 270

 Arg Ala His Ala Asn Pro Gly Leu Arg Pro Leu Val Trp Arg Gly
                 275                 280                 285

 Leu Pro Phe Val Thr Ser Leu Ala Phe Phe Asn Ser Val Ala Asn
                 290                 295                 300

 Pro Val Leu Tyr Val Leu Thr Cys Pro Asp Met Leu Arg Lys Leu
                 305                 310                 315

 Arg Arg Ser Leu Arg Thr Val Leu Glu Ser Val Leu Val Asp Asp
                 320                 325                 330

 Ser Glu Leu Gly Gly Ala Gly Ser Ser Arg Arg Arg Arg Thr Ser
                 335                 340                 345

 Ser Thr Ala Arg Ser Ala Ser Pro Leu Ala Leu Cys Ser Arg Pro
                 350                 355                 360

 Glu Glu Pro Arg Gly Pro Ala Arg Leu Leu Gly Trp Leu Leu Gly
                 365                 370                 375

 Ser Cys Ala Ala Ser Pro Gln Thr Gly Pro Leu Asn Arg Ala Leu
                 380                 385                 390

 Ser Ser Thr Ser Ser
                 395

<210> 5629
<211> 2391
<212> DNA
<213> Homo sapien

<400> 5629
 cgcaaccgga actagccttc tgggggccgg cttggtttat ctctggcggc 50

 cttgtagtcg tctccgagac tccccacccc tccttccctc ttgaccccct 100

 aggtttgatt gccctttccc cgaaacaact atcatgagcg cgaggctgcc 150

 ggtgttgtct ccacctcggt ggccgcggct gttgctgctg tcgctgctcc 200

 tgctgggggc ggttcctggc ccgcgccgga gcggcgcttt ctacctgccc 250

 ggcctggcgc ccgtcaactt ctgcgacgaa gaaaaaaaga gcgacgagtg 300

 caaggccgaa atagaactat ttgtgaacag acttgattca gtggaatcag 350

 ttcttcctta tgaatacaca gcgtttgatt tttgccaagc atcagaagga 400

 aagcgcccat ctgaaaatct tggtcaggta ctattcgggg aaagaattga 450

 accttcacca tataagttta cgtttaataa gaaggagacc tgtaagcttg 500

 tttgtacaaa aacataccat acagagaaag ctgaagacaa acaaaagtta 550

 gaattcttga aaaaaagcat gttattgaat tatcaacatc actggattgt 600

 ggataatatg cctgtaacgt ggtgttacga tgttgaagat ggtcagaggt 650

 tctgtaatcc tggatttcct attggctgtt acattacaga taaaggccat 700

 gcaaaagatg cctgtgttat tagttcagat ttccatgaaa gagatacatt 750

 ttacatcttc aaccatgttg acatcaaaat atactatcat gttgttgaaa 800

 ctgggtccat gggagcaaga ttagtggctg ctaaacttga accgaaaagc 850

 ttcaaacata cccatataga taaaccagac tgctcagggc cccccatgga 900

 cataagtaac aaggcttctg gggagataaa aattgcctat acttactctg 950

 ttagcttcga ggaagatgat aagatcagat gggcgtctag atgggactat 1000

 attctggagt ctatgcctca tacccacatt cagtggttta gcattatgaa 1050

 ttccctggtc attgttctct tcttatctgg aatggtagct atgattatgt 1100

 tacggacact gcacaaagat attgctagat ataatcagat ggactctacg 1150

 gaagatgccc aggaagaatt tggctggaaa cttgttcatg gtgatatatt 1200

 ccgtcctcca agaaaaggga tgctgctatc agtctttcta ggatccggga 1250

 cacagatttt aattatgacc tttgtgactc tatttttcgc ttgcctggga 1300

 tttttgtcac ctgccaaccg aggagcgctg atgacgtgtg ctgtggtcct 1350

 gtgggtgctg ctgggcaccc ctgcaggcta tgttgctgcc agattctata 1400

 agtcctttgg aggtgagaag tggaaaacaa atgttttatt aacatcattt 1450

 ctttgtcctg ggattgtatt tgctgacttc tttataatga atctgatcct 1500

 ctggggagaa ggatcttcag cagctattcc ttttgggaca ctggttgcca 1550

 tattggccct ttggttctgc atatctgtgc ctctgacgtt tattggtgca 1600

 tactttggtt ttaagaagaa tgccattgaa cacccagttc gaaccaatca 1650

 gattccacgt cagattcctg aacagtcgtt ctacacgaag cccttgcctg 1700

 gtattatcat gggagggatt ttgccctttg gctgcatctt tatacaactt 1750

 ttcttcattc tgaatagtat ttggtcacac cagatgtatt acatgtttgg 1800

 cttcctattt ctggtgttta tcattttggt tattacctgt tctgaagcaa 1850

 ctatacttct ttgctatttc cacctatgtg cagaggatta tcattggcaa 1900

 tggcgttcat tccttacgag tggctttact gcagtttatt tcttaatcta 1950

 tgcagtacac tacttctttt caaaactgca gatcacggga acagcaagca 2000

 caattctgta ctttggttat accatgataa tggttttgat cttctttctt 2050

 tttacaggaa caattggctt ctttgcatgc ttttggtttg ttaccaaaat 2100

 atacagtgtg gtgaaggttg actgaagaag tccagtgtgt ccagttaaaa 2150

 cagaaataaa ttaaactctt catcaacaaa gacctgtttt tgtgactgcc 2200

 ttgagtttta tcagaattat tggcctagta atccttcaga aacaccgtaa 2250

 ttctaaataa acctcttccc atacaccttt cccccataag atctgtcttc 2300

 aacactataa agcatttgta ttgtgatttg attaagtata tatttggttg 2350

 ttctcaatga agagcaaatt taaatattat gtgcatttga a 2391

<210> 5630
<211> 663
<212> PRT
<213> Homo sapien

<400> 5630
 Met Ser Ala Arg Leu Pro Val Leu Ser Pro Pro Arg Trp Pro Arg
   1               5                  10                  15

 Leu Leu Leu Leu Ser Leu Leu Leu Leu Gly Ala Val Pro Gly Pro
                  20                  25                  30

 Arg Arg Ser Gly Ala Phe Tyr Leu Pro Gly Leu Ala Pro Val Asn
                  35                  40                  45

 Phe Cys Asp Glu Glu Lys Lys Ser Asp Glu Cys Lys Ala Glu Ile
                  50                  55                  60

 Glu Leu Phe Val Asn Arg Leu Asp Ser Val Glu Ser Val Leu Pro
                  65                  70                  75

 Tyr Glu Tyr Thr Ala Phe Asp Phe Cys Gln Ala Ser Glu Gly Lys
                  80                  85                  90

 Arg Pro Ser Glu Asn Leu Gly Gln Val Leu Phe Gly Glu Arg Ile
                  95                 100                 105

 Glu Pro Ser Pro Tyr Lys Phe Thr Phe Asn Lys Lys Glu Thr Cys
                 110                 115                 120

 Lys Leu Val Cys Thr Lys Thr Tyr His Thr Glu Lys Ala Glu Asp
                 125                 130                 135

 Lys Gln Lys Leu Glu Phe Leu Lys Lys Ser Met Leu Leu Asn Tyr
                 140                 145                 150

 Gln His His Trp Ile Val Asp Asn Met Pro Val Thr Trp Cys Tyr
                 155                 160                 165

 Asp Val Glu Asp Gly Gln Arg Phe Cys Asn Pro Gly Phe Pro Ile
                 170                 175                 180

 Gly Cys Tyr Ile Thr Asp Lys Gly His Ala Lys Asp Ala Cys Val
                 185                 190                 195

 Ile Ser Ser Asp Phe His Glu Arg Asp Thr Phe Tyr Ile Phe Asn
                 200                 205                 210

 His Val Asp Ile Lys Ile Tyr Tyr His Val Val Glu Thr Gly Ser
                 215                 220                 225

 Met Gly Ala Arg Leu Val Ala Ala Lys Leu Glu Pro Lys Ser Phe
                 230                 235                 240

 Lys His Thr His Ile Asp Lys Pro Asp Cys Ser Gly Pro Pro Met
                 245                 250                 255

 Asp Ile Ser Asn Lys Ala Ser Gly Glu Ile Lys Ile Ala Tyr Thr
                 260                 265                 270

 Tyr Ser Val Ser Phe Glu Glu Asp Asp Lys Ile Arg Trp Ala Ser
                 275                 280                 285

 Arg Trp Asp Tyr Ile Leu Glu Ser Met Pro His Thr His Ile Gln
                 290                 295                 300

 Trp Phe Ser Ile Met Asn Ser Leu Val Ile Val Leu Phe Leu Ser
                 305                 310                 315

 Gly Met Val Ala Met Ile Met Leu Arg Thr Leu His Lys Asp Ile
                 320                 325                 330

 Ala Arg Tyr Asn Gln Met Asp Ser Thr Glu Asp Ala Gln Glu Glu
                 335                 340                 345

 Phe Gly Trp Lys Leu Val His Gly Asp Ile Phe Arg Pro Pro Arg
                 350                 355                 360

 Lys Gly Met Leu Leu Ser Val Phe Leu Gly Ser Gly Thr Gln Ile
                 365                 370                 375

 Leu Ile Met Thr Phe Val Thr Leu Phe Phe Ala Cys Leu Gly Phe
                 380                 385                 390

 Leu Ser Pro Ala Asn Arg Gly Ala Leu Met Thr Cys Ala Val Val
                 395                 400                 405

 Leu Trp Val Leu Leu Gly Thr Pro Ala Gly Tyr Val Ala Ala Arg
                 410                 415                 420

 Phe Tyr Lys Ser Phe Gly Gly Glu Lys Trp Lys Thr Asn Val Leu
                 425                 430                 435

 Leu Thr Ser Phe Leu Cys Pro Gly Ile Val Phe Ala Asp Phe Phe
                 440                 445                 450

 Ile Met Asn Leu Ile Leu Trp Gly Glu Gly Ser Ser Ala Ala Ile
                 455                 460                 465

 Pro Phe Gly Thr Leu Val Ala Ile Leu Ala Leu Trp Phe Cys Ile
                 470                 475                 480

 Ser Val Pro Leu Thr Phe Ile Gly Ala Tyr Phe Gly Phe Lys Lys
                 485                 490                 495

 Asn Ala Ile Glu His Pro Val Arg Thr Asn Gln Ile Pro Arg Gln
                 500                 505                 510

 Ile Pro Glu Gln Ser Phe Tyr Thr Lys Pro Leu Pro Gly Ile Ile
                 515                 520                 525

 Met Gly Gly Ile Leu Pro Phe Gly Cys Ile Phe Ile Gln Leu Phe
                 530                 535                 540

 Phe Ile Leu Asn Ser Ile Trp Ser His Gln Met Tyr Tyr Met Phe
                 545                 550                 555

 Gly Phe Leu Phe Leu Val Phe Ile Ile Leu Val Ile Thr Cys Ser
                 560                 565                 570

 Glu Ala Thr Ile Leu Leu Cys Tyr Phe His Leu Cys Ala Glu Asp
                 575                 580                 585

 Tyr His Trp Gln Trp Arg Ser Phe Leu Thr Ser Gly Phe Thr Ala
                 590                 595                 600

 Val Tyr Phe Leu Ile Tyr Ala Val His Tyr Phe Phe Ser Lys Leu
                 605                 610                 615

 Gln Ile Thr Gly Thr Ala Ser Thr Ile Leu Tyr Phe Gly Tyr Thr
                 620                 625                 630

 Met Ile Met Val Leu Ile Phe Phe Leu Phe Thr Gly Thr Ile Gly
                 635                 640                 645

 Phe Phe Ala Cys Phe Trp Phe Val Thr Lys Ile Tyr Ser Val Val
                 650                 655                 660

 Lys Val Asp


<210> 5631
<211> 1552
<212> DNA
<213> Homo sapien

<400> 5631
 acagactgca gggctgacta gggttagttt ggaggaggga gtaagaggtg 50

 gggaggagga ggcacagtta atggatctgt aaacttgcac cctctttcag 100

 agtggtacat ggaagacagc acaaagtgga tccatactct gaaatgcagt 150

 aactctgatg cttgaatttg tctcccttct tgccagaaag gattctaata 200

 actcggtgtc aaagccaaga cataaactca accccttctc ttccaaaagc 250

 ttcacgttac agcatggaag ctgttgccaa gtttgatttc actgcttcag 300

 gtgaggatga actgagcttt cacactggag atgttttgaa gattttaagt 350

 aaccaagagg agtggtttaa ggcggagctt gggagccagg aaggatatgt 400

 gcccaagaat ttcatagaca tccagtttcc caaatggttt cacgaaggcc 450

 tctctcgaca ccaggcagag aacttactca tgggcaagga ggttggcttc 500

 ttcatcatcc gggccagcca gagctcccca ggggacttct ccatctctgt 550

 caggcatgag gatgacgttc aacacttcaa ggtcatgcga gacaacaagg 600

 gtaattactt tctgtggact gagaagtttc catccctaaa taagctggta 650

 gactactaca ggacaaattc catctccaga cagaagcaga tcttccttag 700

 agacagaacc cgagaagacc agggtcaccg gggcaacagc ctggaccgga 750

 ggtcccaggg aggcccacac ctcagtgggg ctgtgggaga agaaatccga 800

 ccttcgatga accggaagct gtcggatcac cccccgaccc ttcccctgca 850

 gcagcaccag caccagccac agcctccgca atatgcccca gcgccccagc 900

 agctgcagca gcccccacag cagcgatatc tgcagcacca ccatttccac 950

 caggaacgcc gaggaggcag ccttgacata aatgatgggc attgtggcac 1000

 cggcttgggc agtgaaatga atgcggccct catgcatcgg agacacacag 1050

 acccagtgca gctccaggcg gcagggcgag tgcggtgggc ccgggcgctg 1100

 tatgactttg aggccctgga ggatgacgag ctggggttcc acagcgggga 1150

 ggtggtggag gtcctggata gctccaaccc atcctggtgg accggccgcc 1200

 tgcacaacaa gctgggcctc ttccctgcca actacgtggc acccatgacc 1250

 cgataaactc ttcaggggac agaagctttt tgtctggagc tgcccacaag 1300

 aaagagggca aggaaaaaag gctggactcc atgactatat atacatacat 1350

 ctatctacat ctgcctgtgt acacacacaa ctttttatac tagtaattta 1400

 ttggcaattg ggctggtaat tagttgatgc aaaagggaac tcaggtggag 1450

 aataatattg acacttgctt ttctgccccc ctcaggggtg tgtggaaggc 1500

 agtgggggag ttgggagggg ggcagggaaa tgaaatggag ttttgtcctg 1550

 gc 1552

<210> 5632
<211> 330
<212> PRT
<213> Homo sapien

<400> 5632
 Met Glu Ala Val Ala Lys Phe Asp Phe Thr Ala Ser Gly Glu Asp
   1               5                  10                  15

 Glu Leu Ser Phe His Thr Gly Asp Val Leu Lys Ile Leu Ser Asn
                  20                  25                  30

 Gln Glu Glu Trp Phe Lys Ala Glu Leu Gly Ser Gln Glu Gly Tyr
                  35                  40                  45

 Val Pro Lys Asn Phe Ile Asp Ile Gln Phe Pro Lys Trp Phe His
                  50                  55                  60

 Glu Gly Leu Ser Arg His Gln Ala Glu Asn Leu Leu Met Gly Lys
                  65                  70                  75

 Glu Val Gly Phe Phe Ile Ile Arg Ala Ser Gln Ser Ser Pro Gly
                  80                  85                  90

 Asp Phe Ser Ile Ser Val Arg His Glu Asp Asp Val Gln His Phe
                  95                 100                 105

 Lys Val Met Arg Asp Asn Lys Gly Asn Tyr Phe Leu Trp Thr Glu
                 110                 115                 120

 Lys Phe Pro Ser Leu Asn Lys Leu Val Asp Tyr Tyr Arg Thr Asn
                 125                 130                 135

 Ser Ile Ser Arg Gln Lys Gln Ile Phe Leu Arg Asp Arg Thr Arg
                 140                 145                 150

 Glu Asp Gln Gly His Arg Gly Asn Ser Leu Asp Arg Arg Ser Gln
                 155                 160                 165

 Gly Gly Pro His Leu Ser Gly Ala Val Gly Glu Glu Ile Arg Pro
                 170                 175                 180

 Ser Met Asn Arg Lys Leu Ser Asp His Pro Pro Thr Leu Pro Leu
                 185                 190                 195

 Gln Gln His Gln His Gln Pro Gln Pro Pro Gln Tyr Ala Pro Ala
                 200                 205                 210

 Pro Gln Gln Leu Gln Gln Pro Pro Gln Gln Arg Tyr Leu Gln His
                 215                 220                 225

 His His Phe His Gln Glu Arg Arg Gly Gly Ser Leu Asp Ile Asn
                 230                 235                 240

 Asp Gly His Cys Gly Thr Gly Leu Gly Ser Glu Met Asn Ala Ala
                 245                 250                 255

 Leu Met His Arg Arg His Thr Asp Pro Val Gln Leu Gln Ala Ala
                 260                 265                 270

 Gly Arg Val Arg Trp Ala Arg Ala Leu Tyr Asp Phe Glu Ala Leu
                 275                 280                 285

 Glu Asp Asp Glu Leu Gly Phe His Ser Gly Glu Val Val Glu Val
                 290                 295                 300

 Leu Asp Ser Ser Asn Pro Ser Trp Trp Thr Gly Arg Leu His Asn
                 305                 310                 315

 Lys Leu Gly Leu Phe Pro Ala Asn Tyr Val Ala Pro Met Thr Arg
                 320                 325                 330

<210> 5633
<211> 3203
<212> DNA
<213> Homo sapien

<400> 5633
 ccacgcgtcc gcaaggtact agtcctaatt ggtatttcaa atagtccttt 50

 taaagccata cttgagtatt tgatgaagtg atttggccgt tttctctctg 100

 gttctaatgt tttttctctt gtctatatag aagtaagtta gctctctgaa 150

 cttcttcaag gtttgagagt ttctataatg ttgagaataa attgaaactg 200

 cagttttagt ggacataagg acttctataa aaagaagtaa agtataatca 250

 agtataattt taaatgtttc cttgcaaaaa aaaatctaaa caatgttttc 300

 acatttagct cttttaagag aattttttaa aaaatgctct aaccatttat 350

 catcttctca attccacaga aatatccaga gaagttgtat tttgagggcc 400

 tcgcggaaca ggtggatcct cctgtacaga tccagtctcc ctatctgccc 450

 atctattttg ggaatgtgtg tcttcgattc cttccagtat ttgatatagt 500

 aatccacaga tttttagagt tgcttccggt atccaaatca ctggagactc 550

 tactggatca tctaggaggc ttatataaat ttcatgatcg tccagtgact 600

 tatctgtata acactctgca ctattatgaa atgcacctga gagaccgcgc 650

 atttctcaaa cgaaaactcg tccatgcgat cattggctct ctgaaggata 700

 atcgaccgca gggctggtgt ctaagtgaca cttacctgaa atgcgctatg 750

 aatgcacgag aggaaaatcc ttgggttcca gatgacacct actattgcag 800

 attgattggc agactagtcg atacgatggc tggcaaatct cctggtccct 850

 ttccaaactg tgactggaga ttcaatgagt ttcccaaccc agctgcccat 900

 gctctccatg ttacttgtgt ggagctcatg gccttggcag tttcaggcaa 950

 agaagttggg aatgcccttc taaatgttgt cctaaaaagg tatgtattct 1000

 ggttcatgca gtaagatttg ttgtttattt gtaaatagaa tggtattcta 1050

 tttcaaactt ttaagacaaa cctgttgccg caaggctgat gcacattgga 1100

 tgatgactgt tttctggttc cagatcttgt ctttgtgata taggagttat 1150

 ggaatgagcc ctggacagga tcctaagatc cgggtttgtt cctacttcta 1200

 ctcattaata gcagtttgac atttaatata ggaataatgt taacttgtca 1250

 cttaaaacaa gattctcttc atcttgtttt caagatttca agattctttt 1300

 aaaaattagc atgaagtatg ggataatgat tggggaggaa gtatttttaa 1350

 aaagccttct tgagttttta tgcatattac atttttattc aataaaaaat 1400

 tccccattgt tttattgaaa tggattagtt gtcgatcctc tgaattagac 1450

 atattcttta aaaataagat ccgttgtcag ccatctaaaa tgtttttata 1500

 aattcatact tacattcttt tttgccggtt gcagtcagcc tttagtgcca 1550

 agagagaaca ttacagcatg gatgaatgca attggtttga tcatcactgc 1600

 cctaccagag ccatattgga ttgttcttca tgatcgaatt gtgagtgtca 1650

 tcagcagccc cagcttgacg tctgaaacag agtgggttgg ctatccattc 1700

 cgcctctttg atttcactgc ctgtcatcag tcctactctg agatgagttg 1750

 tagctatacg ttagctcttg cacatgctgt gtggcaccat tctagcatcg 1800

 gacaactttc tctcattcca aagtttctta ctgaagtact tcttcctata 1850

 gtgaagaccg aattccagtt gctttatgta taccatcttg ttggaccatt 1900

 tttacaaaga tttcagcaag agagaactcg ttgtatgata gagattggtg 1950

 tggcgtttta tgacatgctg ctgaatgttg accagtgtag cacccattta 2000

 aattacatgg atcccatctg tgacttcctc tatcacatga agtatatgtt 2050

 tactggtgac agcgtgaaag agcaagtaga gaagattatc tgtaacttaa 2100

 aaccagcttt aaaacttcgt cttcgattca tcacacacat tagcaagatg 2150

 gagccagctg cagtgcctcc acaagccatg aacagtgggt ctccagcatc 2200

 tcagtctaat caggtgcccg tgtctttacc agtaactcag tgaagccaga 2250

 ctgtactgtg gagaaagtag aaatatatcc gtctttgaga gtggactcaa 2300

 accttttaaa tctgaatgcg atcacactgt agtgatatag tagaagcagt 2350

 gatgatattc agattgtttt attttgattc aaatgatgaa tctgttgaca 2400

 ccttataact cccatctccc tatctatatt tttgtctcta agagatcaag 2450

 taagatacat gttgttcata ttcataacaa cttattagag ctatgtagga 2500

 acatagaggt atctgtgatc aaatgacttg tcattggcac tttcagtctt 2550

 tcctattcta gccgttgttt ttgtttgtat tttttattat taatgacata 2600

 tttagtcttc agatatatta ttttaaaggc accacacatg taaaacagtt 2650

 attacaaata ttttatacat aaatctcttg gtagattttc agaataatag 2700

 agatttatat caagaaaagg aatctagatt ttgttgcatt gtaggagcaa 2750

 acaaggcttc atattctttt taaaatgact tgaaatttta ttataaattt 2800

 ccatagtttc tatcaaggtc aactggcagt tttattacct ttgctatgga 2850

 cttgaactta ctgtataaaa ttagttggaa gccatgtaag aaaataacat 2900

 ctgaaaattc ttgaacttaa aatcatgctt aaatggttga ttctccaatt 2950

 tcttttttta aaaataagtt aattgctttt gcaggttgac actctcacct 3000

 gacagatgat gtaattcttc aatttttata atcttaaaat ttttaaattt 3050

 tatatttgta aatacagtac acattttatt tcttggattt tgagagacat 3100

 tgttaatttt gggggaattg gcattgcgaa agacttgaaa actaatgagt 3150

 aaagtctgct gaatgaataa accgtgtgat tgttaaaaaa aaaaaaaaaa 3200

 agg 3203

<210> 5634
<211> 223
<212> PRT
<213> Homo sapien

<400> 5634
 Met Asn Ala Ile Gly Leu Ile Ile Thr Ala Leu Pro Glu Pro Tyr
   1               5                  10                  15

 Trp Ile Val Leu His Asp Arg Ile Val Ser Val Ile Ser Ser Pro
                  20                  25                  30

 Ser Leu Thr Ser Glu Thr Glu Trp Val Gly Tyr Pro Phe Arg Leu
                  35                  40                  45

 Phe Asp Phe Thr Ala Cys His Gln Ser Tyr Ser Glu Met Ser Cys
                  50                  55                  60

 Ser Tyr Thr Leu Ala Leu Ala His Ala Val Trp His His Ser Ser
                  65                  70                  75

 Ile Gly Gln Leu Ser Leu Ile Pro Lys Phe Leu Thr Glu Val Leu
                  80                  85                  90

 Leu Pro Ile Val Lys Thr Glu Phe Gln Leu Leu Tyr Val Tyr His
                  95                 100                 105

 Leu Val Gly Pro Phe Leu Gln Arg Phe Gln Gln Glu Arg Thr Arg
                 110                 115                 120

 Cys Met Ile Glu Ile Gly Val Ala Phe Tyr Asp Met Leu Leu Asn
                 125                 130                 135

 Val Asp Gln Cys Ser Thr His Leu Asn Tyr Met Asp Pro Ile Cys
                 140                 145                 150

 Asp Phe Leu Tyr His Met Lys Tyr Met Phe Thr Gly Asp Ser Val
                 155                 160                 165

 Lys Glu Gln Val Glu Lys Ile Ile Cys Asn Leu Lys Pro Ala Leu
                 170                 175                 180

 Lys Leu Arg Leu Arg Phe Ile Thr His Ile Ser Lys Met Glu Pro
                 185                 190                 195

 Ala Ala Val Pro Pro Gln Ala Met Asn Ser Gly Ser Pro Ala Ser
                 200                 205                 210

 Gln Ser Asn Gln Val Pro Val Ser Leu Pro Val Thr Gln
                 215                 220

<210> 5635
<211> 2791
<212> DNA
<213> Homo sapien

<400> 5635
 acgcgtccgg ccgcggccgg aggtatccgc atcggcgagc tgcgtctccc 50

 gggtgtcggc cccggcggct ccccgaccgt gcccggctgt ggcgaggcgg 100

 ctccagccca gcctgtggca gccgcgaccc ccggggcgct ccggagccca 150

 ctgcgcggcg cgcgtgccgg ctgcctgcat ggacgcggca ctgaagcgga 200

 gccgctcgga ggagccagcc gaaatcctgc cgcctgcccg ggacgaggag 250

 gaggaggagg aagaggggat ggagcagggg ctggaggagg aagaagaggt 300

 ggatccccgg atccagggag aactggagaa gttaaatcag tccacggatg 350

 atatcaacag acgggagact gaacttgagg atgctcgtca gaagttccgc 400

 tctgttctgg ttgaagcaac ggtgaaactg gatgaactgg tgaagaaaat 450

 tggcaaagct gtggaagact ccaagcccta ctgggaggca cggagggtgg 500

 cgaggcaggc tcagctggaa gctcagaaag ccacgcagga cttccagagg 550

 gccacagagg tgctccgcgc cgccaaggag acatctccct ggccgagcag 600

 cggctgctgg aggatgacaa gcggcagttc gactccgcct ggcaggagat 650

 gctgaatcac gccactcaga gggtcatgga ggcggagcag accaagacca 700

 ggagcgagct ggtgcataag gagacggcag ccaggtacaa tgccgccatg 750

 ggccgcatgc gacagctgga gaagaaactc aagagagcca tcaacaagtc 800

 caagccttat tttgaactca aggcaaagta ctatgtgcag ctcgagcaac 850

 tgaaaaagac tgtggatgac ctgcaggcca aactgaccct ggcaaaaggc 900

 gagtacaaga tggccctgaa gaacctggag atgatctcag atgagatcca 950

 cgagcggcgg cgctccagtg ccatggggcc tcggggatgc ggtgttggtg 1000

 ctgagggcag cagcacatct gtggaggatc tgccagggag caaacctgag 1050

 cctgatgcca tttctgtggc ctcggaggcc tttgaagatg acagctgtag 1100

 caactttgtg tctgaagatg actcggaaac ccagtccgtg tccagcttta 1150

 gttcaggacc aacaagcccg tctgagatgc ctgaccagtt ccctgcggtt 1200

 gtgaggcctg gcagcctgga tctgcccagc cctgtgtccc tgtcagagtt 1250

 tgggatgatg ttcccagtgt tgggccctcg aagtgaatgc agcggggcct 1300

 cctcccctga atgtgaagta gaacgaggag acagggcaga aggggcagag 1350

 aataaaacaa gtgacaaagc caacaacaac cggggcctca gcagtagcag 1400

 tggcagtggt ggcagcagta agagccaaag cagcacctcc cctgagggcc 1450

 aggccttgga gaaccggatg aagcagctct ccctacagtg ctcaaaggga 1500

 agagatggaa ttattgctga cataaaaatg gtgcagattg gctgattcat 1550

 cctgggccct ggccgatgtg catatcaaca tttatacatg gaactggaga 1600

 acattgtgcc aataatcatt taatatatgc caaatcttac acgtctactc 1650

 taaactgctc taatgaagtt tcagtgacct tgagggctaa agattgttct 1700

 tctgggtaag agctcttggg ctggtttttc agagcagagt tcttgttgtg 1750

 ggtagactgt gactaggttc acagcctttg tggaacattc cgtataacgg 1800

 cattgtggaa gcaataacta gttcctatga aagaaccaga gctgggaaga 1850

 tggctgggaa gccaggccaa agtgggggca acagcttgct tctctttctc 1900

 ttctcaccct cagtttgtat gggaaaatgg agatgtcctc tccactttat 1950

 cccacgatat ctaaatgaaa aagaaagaaa acccacacac aaagcaaaaa 2000

 ctcaagtatt aagagcacat atttttgacc cagtggaggc ttaaaaaaaa 2050

 aaaaatccaa gaacacaatt cattttcacc acctctggtg ttcagagggg 2100

 gcttttaaaa aagcgtgtat gctgggatac ccattaaaac cattttctag 2150

 aaggctacca tgagctgcac tttttggggt gggaaaggtg aatgccagtg 2200

 gggatgcggg gggatgaggg taggagggac ttatagaagg ggatttgtgg 2250

 ctgtggggga gaaggttcta cagcataagc cttatcctgc cagccaaggg 2300

 gatttattct aagagaagtg catgtgaaga atggttgcca ctgttattag 2350

 attgacaaga tgttaatttc tctgtaggtt gtaactttaa aaataaatga 2400

 aattatttaa gggttatgct gcactagtat tccttagagg aaacagttct 2450

 ttaaagttag gaaagggagt aggcaggcat gtgttggcaa aggctgttaa 2500

 tagtagttaa gtgttaagac tgcttttctt taacgttttc atggtaatgc 2550

 atatttagag cactgtattt ttgtcttgtt aagaaaattt agcatttcta 2600

 aaagaaaaaa gcaaccctct ttcaaactgt taattctgtc acagcctgta 2650

 tattttagtc atttgtaaat ctcttcatac aatagtgact tcttttttga 2700

 ctgatacagt atcttaatta caaggttatt ttgtacttgt cttaatacac 2750

 taagtgtaat aaaaacggct tgagaaaaaa aaaaaaaaaa a 2791

<210> 5636
<211> 514
<212> PRT
<213> Homo sapien

<400> 5636
 Arg Val Arg Pro Arg Pro Glu Val Ser Ala Ser Ala Ser Cys Val
   1               5                  10                  15

 Ser Arg Val Ser Ala Pro Ala Ala Pro Arg Pro Cys Pro Ala Val
                  20                  25                  30

 Ala Arg Arg Leu Gln Pro Ser Leu Trp Gln Pro Arg Pro Pro Gly
                  35                  40                  45

 Arg Ser Gly Ala His Cys Ala Ala Arg Val Pro Ala Ala Cys Met
                  50                  55                  60

 Asp Ala Ala Leu Lys Arg Ser Arg Ser Glu Glu Pro Ala Glu Ile
                  65                  70                  75

 Leu Pro Pro Ala Arg Asp Glu Glu Glu Glu Glu Glu Glu Gly Met
                  80                  85                  90

 Glu Gln Gly Leu Glu Glu Glu Glu Glu Val Asp Pro Arg Ile Gln
                  95                 100                 105

 Gly Glu Leu Glu Lys Leu Asn Gln Ser Thr Asp Asp Ile Asn Arg
                 110                 115                 120

 Arg Glu Thr Glu Leu Glu Asp Ala Arg Gln Lys Phe Arg Ser Val
                 125                 130                 135

 Leu Val Glu Ala Thr Val Lys Leu Asp Glu Leu Val Lys Lys Ile
                 140                 145                 150

 Gly Lys Ala Val Glu Asp Ser Lys Pro Tyr Trp Glu Ala Arg Arg
                 155                 160                 165

 Val Ala Arg Gln Ala Gln Leu Glu Ala Gln Lys Ala Thr Gln Asp
                 170                 175                 180

 Phe Gln Arg Ala Thr Glu Val Leu Arg Ala Ala Lys Glu Thr Ser
                 185                 190                 195

 Pro Trp Pro Ser Ser Gly Cys Trp Arg Met Asp Lys Arg Gln Phe
                 200                 205                 210

 Asp Ser Ala Trp Gln Glu Met Leu Asn His Ala Thr Gln Arg Val
                 215                 220                 225

 Met Glu Ala Glu Gln Thr Lys Thr Arg Ser Glu Leu Val His Lys
                 230                 235                 240

 Glu Thr Ala Ala Arg Tyr Asn Ala Ala Met Gly Arg Met Arg Gln
                 245                 250                 255

 Leu Glu Lys Lys Leu Lys Arg Ala Ile Asn Lys Ser Lys Pro Tyr
                 260                 265                 270

 Phe Glu Leu Lys Ala Lys Tyr Tyr Val Gln Leu Glu Gln Leu Lys
                 275                 280                 285

 Lys Thr Val Asp Asp Leu Gln Ala Lys Leu Thr Leu Ala Lys Gly
                 290                 295                 300

 Glu Tyr Lys Met Ala Leu Lys Asn Leu Glu Met Ile Ser Asp Glu
                 305                 310                 315

 Ile His Glu Arg Arg Arg Ser Ser Ala Met Gly Pro Arg Gly Cys
                 320                 325                 330

 Gly Val Gly Ala Glu Gly Ser Ser Thr Ser Val Glu Asp Leu Pro
                 335                 340                 345

 Gly Ser Lys Pro Glu Pro Asp Ala Ile Ser Val Ala Ser Glu Ala
                 350                 355                 360

 Phe Glu Asp Asp Ser Cys Ser Asn Phe Val Ser Glu Asp Asp Ser
                 365                 370                 375

 Glu Thr Gln Ser Val Ser Ser Phe Ser Ser Gly Pro Thr Ser Pro
                 380                 385                 390

 Ser Glu Met Pro Asp Gln Phe Pro Ala Val Val Arg Pro Gly Ser
                 395                 400                 405

 Leu Asp Leu Pro Ser Pro Val Ser Leu Ser Glu Phe Gly Met Met
                 410                 415                 420

 Phe Pro Val Leu Gly Pro Arg Ser Glu Cys Ser Gly Ala Ser Ser
                 425                 430                 435

 Pro Glu Cys Glu Val Glu Arg Gly Asp Arg Ala Glu Gly Ala Glu
                 440                 445                 450

 Asn Lys Thr Ser Asp Lys Ala Asn Asn Asn Arg Gly Leu Ser Ser
                 455                 460                 465

 Ser Ser Gly Ser Gly Gly Ser Ser Lys Ser Gln Ser Ser Thr Ser
                 470                 475                 480

 Pro Glu Gly Gln Ala Leu Glu Asn Arg Met Lys Gln Leu Ser Leu
                 485                 490                 495

 Gln Cys Ser Lys Gly Arg Asp Gly Ile Ile Ala Asp Ile Lys Met
                 500                 505                 510

 Val Gln Ile Gly


<210> 5637
<211> 1638
<212> DNA
<213> Homo sapien

<400> 5637
 ggaattccct gatatacacc tggaccacca ccaatggata tacaaatggc 50

 aaacaatttt actccgccct ctgcaactcc tcagggaaat gactgtgacc 100

 tctatgcaca tcacagcacg gccaggatag taatgcctct gcattacagc 150

 ctcgtcttca tcattgggct cgtgggaaac ttactagcct tggtcgtcat 200

 tgttcaaaac aggaaaaaaa tcaactctac caccctctat tcaacaaatt 250

 tggtgatttc tgatatactt tttaccaccg ctttgcctac acgaatagcc 300

 tactatgcaa tgggctttga ctggagaatc ggagatgcct tgtgtaggat 350

 aactgcgcta gtgttttaca tcaacacata tgcaggtgtg aactttatga 400

 cctgcctgag tattgaccgc ttcattgctg tggtgcaccc tctacgctac 450

 aacaagataa aaaggattga acatgcaaaa ggcgtgtgca tatttgtctg 500

 gattctagta tttgctcaga cactcccact cctcatcaac cctatgtcaa 550

 agcaggaggc tgaaaggatt acatgcatgg agtatccaaa ctttgaagaa 600

 actaaatctc ttccctggat tctgcttggg gcatgtttca taggatatgt 650

 acttccactt ataatcattc tcatctgcta ttctcagatc tgctgcaaac 700

 tcttcagaac tgccaaacaa aacccactca ctgagaaatc tggtgtaaac 750

 aaaaaggctc tcaacacaat tattcttatt attgttgtgt ttgttctctg 800

 tttcacacct taccatgttg caattattca acatatgatt aagaagcttc 850

 gtttctctaa tttcctggaa tgtagccaaa gacattcgtt ccagatttct 900

 ctgcacttta cagtatgcct gatgaacttc aattgctgca tggacccttt 950

 tatctacttc tttgcatgta aagggtataa gagaaaggtt atgaggatgc 1000

 tgaaacggca agtcagtgta tcgatttcta gtgctgtgaa gtcagcccct 1050

 gaagaaaatt cacgtgaaat gacagaaacg cagatgatga tacattccaa 1100

 gtcttcaaat ggaaagtgaa atggattgta ttttggttta tagtgacgta 1150

 aactgtatga caaactttgc aggacttccc ttataaagca aaataattgt 1200

 tcagcttcca attagtattc ttttatattt ctttcattgg gcactttccc 1250

 atctccaact cggaagtaag cccaagagaa caacataaag caaacaacat 1300

 aaagcacaat aaaaatgcaa ataaatattt tcatttttat ttgtaaacga 1350

 atacaccaaa aggaggcgct cttaataact cccaatgtaa aaagttttgt 1400

 tttaataaaa aatttaatta ttatttcttg ccaacaaatg gctagaaagg 1450

 actgaataga ttatatattg ccagatgtta atactgtaac atacttttta 1500

 aataacatat ttcttaaatc caaatttctc tcaatgttag atttaattcc 1550

 ctcaataaca ccaatgtttt gttttgtttc gttctgggtc ataaaacttt 1600

 gttaaggaac tcttttggaa taaagagcag gatgctgc 1638

<210> 5638
<211> 361
<212> PRT
<213> Homo sapien

<400> 5638
 Met Asp Ile Gln Met Ala Asn Asn Phe Thr Pro Pro Ser Ala Thr
   1               5                  10                  15

 Pro Gln Gly Asn Asp Cys Asp Leu Tyr Ala His His Ser Thr Ala
                  20                  25                  30

 Arg Ile Val Met Pro Leu His Tyr Ser Leu Val Phe Ile Ile Gly
                  35                  40                  45

 Leu Val Gly Asn Leu Leu Ala Leu Val Val Ile Val Gln Asn Arg
                  50                  55                  60

 Lys Lys Ile Asn Ser Thr Thr Leu Tyr Ser Thr Asn Leu Val Ile
                  65                  70                  75

 Ser Asp Ile Leu Phe Thr Thr Ala Leu Pro Thr Arg Ile Ala Tyr
                  80                  85                  90

 Tyr Ala Met Gly Phe Asp Trp Arg Ile Gly Asp Ala Leu Cys Arg
                  95                 100                 105

 Ile Thr Ala Leu Val Phe Tyr Ile Asn Thr Tyr Ala Gly Val Asn
                 110                 115                 120

 Phe Met Thr Cys Leu Ser Ile Asp Arg Phe Ile Ala Val Val His
                 125                 130                 135

 Pro Leu Arg Tyr Asn Lys Ile Lys Arg Ile Glu His Ala Lys Gly
                 140                 145                 150

 Val Cys Ile Phe Val Trp Ile Leu Val Phe Ala Gln Thr Leu Pro
                 155                 160                 165

 Leu Leu Ile Asn Pro Met Ser Lys Gln Glu Ala Glu Arg Ile Thr
                 170                 175                 180

 Cys Met Glu Tyr Pro Asn Phe Glu Glu Thr Lys Ser Leu Pro Trp
                 185                 190                 195

 Ile Leu Leu Gly Ala Cys Phe Ile Gly Tyr Val Leu Pro Leu Ile
                 200                 205                 210

 Ile Ile Leu Ile Cys Tyr Ser Gln Ile Cys Cys Lys Leu Phe Arg
                 215                 220                 225

 Thr Ala Lys Gln Asn Pro Leu Thr Glu Lys Ser Gly Val Asn Lys
                 230                 235                 240

 Lys Ala Leu Asn Thr Ile Ile Leu Ile Ile Val Val Phe Val Leu
                 245                 250                 255

 Cys Phe Thr Pro Tyr His Val Ala Ile Ile Gln His Met Ile Lys
                 260                 265                 270

 Lys Leu Arg Phe Ser Asn Phe Leu Glu Cys Ser Gln Arg His Ser
                 275                 280                 285

 Phe Gln Ile Ser Leu His Phe Thr Val Cys Leu Met Asn Phe Asn
                 290                 295                 300

 Cys Cys Met Asp Pro Phe Ile Tyr Phe Phe Ala Cys Lys Gly Tyr
                 305                 310                 315

 Lys Arg Lys Val Met Arg Met Leu Lys Arg Gln Val Ser Val Ser
                 320                 325                 330

 Ile Ser Ser Ala Val Lys Ser Ala Pro Glu Glu Asn Ser Arg Glu
                 335                 340                 345

 Met Thr Glu Thr Gln Met Met Ile His Ser Lys Ser Ser Asn Gly
                 350                 355                 360

 Lys


<210> 5639
<211> 2162
<212> DNA
<213> Homo sapien

<400> 5639
 gggctgcgct gtccagctgt ggctatggcc ccagccccga gatgaggagg 50

 gagagaacta ggggcccgca ggcctgggaa tttccgtccc ccaccaagtc 100

 cggatgctca ctccaaagtc tcagcaggcc cctgagggag ggagctgtca 150

 gccagggaaa accgagaaca ccatcaccat gacaaccagt caccagcctc 200

 aggacagata caaagctgtc tggcttatct tcttcatgct gggtctggga 250

 acgctgctcc cgtggaattt tttcatgacg gccactcagt atttcacaaa 300

 ccgcctggac atgtcccaga atgtgtcctt ggtcactgct gaactgagca 350

 aggacgccca ggcgtcagcc gcccctgcag cacccttgcc tgagcggaac 400

 tctctcagtg ccatcttcaa caatgtcatg accctatgtg ccatgctgcc 450

 cctgctgtta ttcacctacc tcaactcctt cctgcatcag aggatccccc 500

 agtccgtacg gatcctgggc agcctggtgg ccatcctgct ggtgtttctg 550

 atcactgcca tcctggtgaa ggtgcagctg gatgctctgc ccttctttgt 600

 catcaccatg atcaagatcg tgctcattaa ttcatttggt gccatcctgc 650

 agggcagcct gtttggtctg gctggccttc tgcctgccag ctacacggcc 700

 cccatcatga gtggccaggg cctagcaggc ttctttgcct ccgtggccat 750

 gatctgcgct attgccagtg gctcggaact atcagaaagt gccttcggct 800

 actttatcac agcctgtgct gttatcattt tgaccatcat ctgttacctg 850

 ggcctgcccc gcctggaatt ctaccgctac taccagcagc tcaagcttga 900

 aggacccggg gagcaggaga ccaagttgga cctcattagc aaaggagagg 950

 agccaagagc aggcaaagag gaatctggag tttcagtctc caactctcag 1000

 cccaccaatg aaagccactc tatcaaagcc atcctgaaaa atatctcagt 1050

 cctggctttc tctgtctgct tcatcttcac tatcaccatt gggatgtttc 1100

 cagccgtgac tgttgaggtc aagtccagca tcgcaggcag cagcacctgg 1150

 gaacgttact tcattcctgt gtcctgtttc ttgactttca atatctttga 1200

 ctggttgggc cggagcctca cagctgtatt catgtggcct gggaaggaca 1250

 gccgctggct gccaagcctg gtgctggccc ggctggtgtt tgtgccactg 1300

 ctgctgctgt gcaacattaa gccccgccgc tacctgactg tggtcttcga 1350

 gcacgatgcc tggttcatct tcttcatggc tgcctttgcc ttctccaacg 1400

 gctacctcgc cagcctctgc atgtgcttcg ggcccaagaa agtgaagcca 1450

 gctgaggcag agaccgcagg agccatcatg gccttcttcc tgtgtctggg 1500

 tctggcactg ggggctgttt tctccttcct gttccgggca attgtgtgac 1550

 aaaggatgga cagaaggact gcctgcctcc ctccctgtct gcctcctgcc 1600

 ccttccttct gccaggggtg atcctgagtg gtctggcggt tttttcttct 1650

 aactgacttc tgctttccac ggcgtgtgct gggcccggat ctccaggccc 1700

 tggggaggga gcctctggac ggacagtggg gacattgtgg gtttggggct 1750

 cagagtcgag ggacggggtg tagcctcggc atttgcttga gtttctccac 1800

 tcttggctct gactgatccc tgcttgtgca ggccagtgga ggctcttggg 1850

 cttggagaac acgtgtgtct ctgtgtatgt gtctgtgtgt ctgcgtccgt 1900

 gtctgtcaga ctgtctgcct gtcctggggt ggctaggagc tgggtctgac 1950

 cgttgtatgg tttgacctga tatactccat tctcccctgc gcctcctcct 2000

 ctgtgttttt tccatgtccc cctcccaact ccccatgccc agtttttacc 2050

 catcatgcac cctgtacagt tgccacgtta ctgccttttt taaaaatata 2100

 tttgacagaa accaggtgcc ttcagaggct ctctgattta aataaacctt 2150

 tcttgttttt tt 2162

<210> 5640
<211> 456
<212> PRT
<213> Homo sapien

<400> 5640
 Met Thr Thr Ser His Gln Pro Gln Asp Arg Tyr Lys Ala Val Trp
   1               5                  10                  15

 Leu Ile Phe Phe Met Leu Gly Leu Gly Thr Leu Leu Pro Trp Asn
                  20                  25                  30

 Phe Phe Met Thr Ala Thr Gln Tyr Phe Thr Asn Arg Leu Asp Met
                  35                  40                  45

 Ser Gln Asn Val Ser Leu Val Thr Ala Glu Leu Ser Lys Asp Ala
                  50                  55                  60

 Gln Ala Ser Ala Ala Pro Ala Ala Pro Leu Pro Glu Arg Asn Ser
                  65                  70                  75

 Leu Ser Ala Ile Phe Asn Asn Val Met Thr Leu Cys Ala Met Leu
                  80                  85                  90

 Pro Leu Leu Leu Phe Thr Tyr Leu Asn Ser Phe Leu His Gln Arg
                  95                 100                 105

 Ile Pro Gln Ser Val Arg Ile Leu Gly Ser Leu Val Ala Ile Leu
                 110                 115                 120

 Leu Val Phe Leu Ile Thr Ala Ile Leu Val Lys Val Gln Leu Asp
                 125                 130                 135

 Ala Leu Pro Phe Phe Val Ile Thr Met Ile Lys Ile Val Leu Ile
                 140                 145                 150

 Asn Ser Phe Gly Ala Ile Leu Gln Gly Ser Leu Phe Gly Leu Ala
                 155                 160                 165

 Gly Leu Leu Pro Ala Ser Tyr Thr Ala Pro Ile Met Ser Gly Gln
                 170                 175                 180

 Gly Leu Ala Gly Phe Phe Ala Ser Val Ala Met Ile Cys Ala Ile
                 185                 190                 195

 Ala Ser Gly Ser Glu Leu Ser Glu Ser Ala Phe Gly Tyr Phe Ile
                 200                 205                 210

 Thr Ala Cys Ala Val Ile Ile Leu Thr Ile Ile Cys Tyr Leu Gly
                 215                 220                 225

 Leu Pro Arg Leu Glu Phe Tyr Arg Tyr Tyr Gln Gln Leu Lys Leu
                 230                 235                 240

 Glu Gly Pro Gly Glu Gln Glu Thr Lys Leu Asp Leu Ile Ser Lys
                 245                 250                 255

 Gly Glu Glu Pro Arg Ala Gly Lys Glu Glu Ser Gly Val Ser Val
                 260                 265                 270

 Ser Asn Ser Gln Pro Thr Asn Glu Ser His Ser Ile Lys Ala Ile
                 275                 280                 285

 Leu Lys Asn Ile Ser Val Leu Ala Phe Ser Val Cys Phe Ile Phe
                 290                 295                 300

 Thr Ile Thr Ile Gly Met Phe Pro Ala Val Thr Val Glu Val Lys
                 305                 310                 315

 Ser Ser Ile Ala Gly Ser Ser Thr Trp Glu Arg Tyr Phe Ile Pro
                 320                 325                 330

 Val Ser Cys Phe Leu Thr Phe Asn Ile Phe Asp Trp Leu Gly Arg
                 335                 340                 345

 Ser Leu Thr Ala Val Phe Met Trp Pro Gly Lys Asp Ser Arg Trp
                 350                 355                 360

 Leu Pro Ser Leu Val Leu Ala Arg Leu Val Phe Val Pro Leu Leu
                 365                 370                 375

 Leu Leu Cys Asn Ile Lys Pro Arg Arg Tyr Leu Thr Val Val Phe
                 380                 385                 390

 Glu His Asp Ala Trp Phe Ile Phe Phe Met Ala Ala Phe Ala Phe
                 395                 400                 405

 Ser Asn Gly Tyr Leu Ala Ser Leu Cys Met Cys Phe Gly Pro Lys
                 410                 415                 420

 Lys Val Lys Pro Ala Glu Ala Glu Thr Ala Gly Ala Ile Met Ala
                 425                 430                 435

 Phe Phe Leu Cys Leu Gly Leu Ala Leu Gly Ala Val Phe Ser Phe
                 440                 445                 450

 Leu Phe Arg Ala Ile Val
                 455

<210> 5641
<211> 5775
<212> DNA
<213> Homo sapien

<400> 5641
 tcctaggcgg cggccgcggc ggcggaggca gcagcggcgg cggcagtggc 50

 ggcggcgaag gtggcggcgg ctcggccagt actcccggcc cccgccattt 100

 cggactggga gcgagcgcgg cgcaggcact gaaggcggcg gcggggccag 150

 aggctcagcg gctcccaggt gcgggagaga ggcctgctga aaatgactga 200

 atataaactt gtggtagttg gagcttgtgg cgtaggcaag agtgccttga 250

 cgatacagct aattcagaat cattttgtgg acgaatatga tccaacaata 300

 gaggattcct acaggaagca agtagtaatt gatggagaaa cctgtctctt 350

 ggatattctc gacacagcag gtcaagagga gtacagtgca atgagggacc 400

 agtacatgag gactggggag ggctttcttt gtgtatttgc cataaataat 450

 actaaatcat ttgaagatat tcaccattat agagaacaaa ttaaaagagt 500

 taaggactct gaagatgtac ctatggtcct agtaggaaat aaatgtgatt 550

 tgccttctag aacagtagac acaaaacagg ctcaggactt agcaagaagt 600

 tatggaattc cttttattga aacatcagca aagacaagac agggtgttga 650

 tgatgccttc tatacattag ttcgagaaat tcgaaaacat aaagaaaaga 700

 tgagcaaaga tggtaaaaag aagaaaaaga agtcaaagac aaagtgtgta 750

 attatgtaaa tacaatttgt acttttttct taaggcatac tagtacaagt 800

 ggtaattttt gtacattaca ctaaattatt agcatttgtt ttagcattac 850

 ctaatttttt tcctgctcca tgcagactgt tagcttttac cttaaatgct 900

 tattttaaaa tgacagtgga agtttttttt tcctcgaagt gccagtattc 950

 ccagagtttt ggtttttgaa ctagcaatgc ctgtgaaaaa gaaactgaat 1000

 acctaagatt tctgtcttgg ggtttttggt gcatgcagtt gattacttct 1050

 tatttttctt accaagtgtg aatgttggtg tgaaacaaat taatgaagct 1100

 tttgaatcat ccctattctg tgttttatct agtcacataa atggattaat 1150

 tactaatttc agttgagacc ttctaattgg tttttactga aacattgagg 1200

 gacacaaatt tatgggcttc ctgatgatga ttcttctagg catcatgtcc 1250

 tatagtttgt catccctgat gaatgtaaag ttacactgtt cacaaaggtt 1300

 ttgtctcctt tccactgcta ttagtcatgg tcactctccc caaaatatta 1350

 tattttttct ataaaaagaa aaaaatggaa aaaaattaca aggcaatgga 1400

 aactattata aggccatttc cttttcacat tagataaatt actataaaga 1450

 ctcctaatag ctttttcctg ttaaggcaga cccagtatga atgggattat 1500

 tatagcaacc attttggggc tatatttaca tgctactaaa tttttataat 1550

 aattgaaaag attttaacaa gtataaaaaa attctcatag gaattaaatg 1600

 tagtctccct gtgtcagact gctctttcat agtataactt taaatctttt 1650

 cttcaacttg agtctttgaa gatagtttta attctgcttg tgacattaaa 1700

 agattatttg ggccagttat agcttattag gtgttgaaga gaccaaggtt 1750

 gcaagccagg ccctgtgtga accttgagct ttcatagaga gtttcacagc 1800

 atggactgtg tgccccacgg tcatccgagt ggttgtacga tgcattggtt 1850

 agtcaaaaat ggggagggac tagggcagtt tggatagctc aacaagatac 1900

 aatctcactc tgtggtggtc ctgctgacaa atcaagagca ttgcttttgt 1950

 ttcttaagaa aacaaactct tttttaaaaa ttacttttaa atattaactc 2000

 aaaagttgag attttggggt ggtggtgtgc caagacatta attttttttt 2050

 taaacaatga agtgaaaaag ttttacaatc tctaggtttg gctagttctc 2100

 ttaacactgg ttaaattaac attgcataaa cacttttcaa gtctgatcca 2150

 tatttaataa tgctttaaaa taaaaataaa aacaatcctt ttgataaatt 2200

 taaaatgtta cttattttaa aataaatgaa gtgagatggc atggtgaggt 2250

 gaaagtatca ctggactagg ttgttggtga cttaggttct agataggtgt 2300

 cttttaggac tctgattttg aggacatcac ttactatcca tttcttcatg 2350

 ttaaaagaag tcatctcaaa ctcttagttt ttttttttta cactatgtga 2400

 tttatattcc atttacataa ggatacactt atttgtcaag ctcagcacaa 2450

 tctgtaaatt tttaacctat gttacaccat cttcagtgcc agtcttgggc 2500

 aaaattgtgc aagaggtgaa gtttatattt gaatatccat tctcgtttta 2550

 ggactcttct tccatattag tgtcatcttg cctccctacc ttccacatgc 2600

 cccatgactt gatgcagttt taatacttgt aattccccta accataagat 2650

 ttactgctgc tgtggatatc tccatgaagt tttcccactg agtcacatca 2700

 gaaatgccct acatcttatt ttcctcaggg ctcaagagaa tctgacagat 2750

 accataaagg gatttgacct aatcactaat tttcaggtgg tggctgatgc 2800

 tttgaacatc tctttgctgc ccaatccatt agcgacagta ggatttttca 2850

 accctggtat gaatagacag aaccctatcc agtggaagga gaatttaata 2900

 aagatagtgc agaaagaatt ccttaggtaa tctataacta ggactactcc 2950

 tggtaacagt aatacattcc attgttttag taaccagaaa tcttcatgca 3000

 atgaaaaata ctttaattca tgaagcttac tttttttttt ttggtgtcag 3050

 agtctcgctc ttgtcaccca ggctggaatg cagtggcgcc atctcagctc 3100

 actgcaacct tccatcttcc caggttcaag cgattctcgt gcctcggcct 3150

 cctgagtagc tgggattaca ggcgtgtgca ctacactcaa ctaatttttg 3200

 tatttttagg agagacgggg tttcacctgt tggccaggct ggtctcgaac 3250

 tcctgacctc aagtgattca cccaccttgg cctcataaac ctgttttgca 3300

 gaactcattt attcagcaaa tatttattga gtgcctacca gatgccagtc 3350

 accgcacaag gcactgggta tatggtatcc ccaaacaaga gacataatcc 3400

 cggtccttag gtactgctag tgtggtctgt aatatcttac taaggccttt 3450

 ggtatacgac ccagagataa cacgatgcgt attttagttt tgcaaagaag 3500

 gggtttggtc tctgtgccag ctctataatt gttttgctac gattccactg 3550

 aaactcttcg atcaagctac tttatgtaaa tcacttcatt gttttaaagg 3600

 aataaacttg attatattgt ttttttattt ggcataactg tgattctttt 3650

 aggacaatta ctgtacacat taaggtgtat gtcagatatt catattgacc 3700

 caaatgtgta atattccagt tttctctgca taagtaatta aaatatactt 3750

 aaaaattaat agttttatct gggtacaaat aaacagtgcc tgaactagtt 3800

 cacagacaag ggaaacttct atgtaaaaat cactatgatt tctgaattgc 3850

 tatgtgaaac tacagatctt tggaacactg tttaggtagg gtgttaagac 3900

 ttgacacagt acctcgtttc tacacagaga aagaaatggc catacttcag 3950

 gaactgcagt gcttatgagg ggatatttag gcctcttgaa tttttgatgt 4000

 agatgggcat ttttttaagg tagtggttaa ttacctttat gtgaactttg 4050

 aatggtttaa caaaagattt gtttttgtag agattttaaa gggggagaat 4100

 tctagaaata aatgttacct aattattaca gccttaaaga caaaaatcct 4150

 tgttgaagtt tttttaaaaa aagactaaat tacatagact taggcattaa 4200

 catgtttgtg gaagaatata gcagacgtat attgtatcat ttgagtgaat 4250

 gttcccaagt aggcattcta ggctctattt aactgagtca cactgcatag 4300

 gaatttagaa cctaactttt ataggttatc aaaactgttg tcaccattgc 4350

 acaattttgt cctaatatat acatagaaac tttgtggggc atgttaagtt 4400

 acagtttgca caagttcatc tcatttgtat tccattgatt tttttttttc 4450

 ttctaaacat tttttcttca aaacagtata tataactttt tttaggggat 4500

 tttttttaga cagcaaaaaa ctatctgaag atttccattt gtcaaaaagt 4550

 aatgatttct tgataattgt gtagtgaatg ttttttagaa cccagcagtt 4600

 accttgaaag ctgaatttat atttagtaac ttctgtgtta atactggata 4650

 gcatgaattc tgcattgaga aactgaatag ctgtcataaa atgctttctt 4700

 tcctaaagaa agatactcac atgagttctt gaagaatagt cataactaga 4750

 ttaagatctg tgttttagtt taatagtttg aagtgcctgt ttgggataat 4800

 gataggtaat ttagatgaat ttaggggaaa aaaaagttat ctgcagttat 4850

 gttgagggcc catctctccc cccacacccc cacagagcta actgggttac 4900

 agtgttttat ccgaaagttt ccaattccac tgtcttgtgt tttcatgttg 4950

 aaaatacttt tgcatttttc ctttgagtgc caatttctta ctagtactat 5000

 ttcttaatgt aacatgttta cctggcctgt cttttaacta tttttgtata 5050

 gtgtaaactg aaacatgcac attttgtaca ttgtgctttc ttttgtgggt 5100

 catatgcagt gtgatccagt tgttttccat catttggttg cgctgaccta 5150

 ggaatgttgg tcatatcaaa cattaaaaat gaccactctt ttaatgaaat 5200

 taacttttaa atgtttatag gagtatgtgc tgtgaagtga tctaaaattt 5250

 gtaatatttt tgtcatgaac tgtactactc ctaattattg taatgtaata 5300

 aaaatagtta cagtgactat gagtgtgtat ttattcatgc aaatttgaac 5350

 tgtttgcccc gaaatggata tggatacttt ataagccata gacactatag 5400

 tataccagtg aatcttttat gcagcttgtt agaagtatcc ttttattttc 5450

 taaaaggtgc tgtggatatt atgtaaaggc gtgtttgctt aaacaatttt 5500

 ccatatttag aagtagatgc aaaacaaatc tgcctttatg acaaaaaaat 5550

 aggataacat tatttattta tttcctttta tcaataaggt aattgataca 5600

 caacaggtga cttggtttta ggcccaaagg tagcagcagc aacattaata 5650

 atggaaataa ttgaatagtt agttatgtat gttaatgcca gtcaccagca 5700

 ggctatttca aggtcagaag taatgactcc atacatatta tttatttcta 5750

 taactacatt taaatcatta ccagg 5775

<210> 5642
<211> 188
<212> PRT
<213> Homo sapien

<400> 5642
 Met Thr Glu Tyr Lys Leu Val Val Val Gly Ala Cys Gly Val Gly
   1               5                  10                  15

 Lys Ser Ala Leu Thr Ile Gln Leu Ile Gln Asn His Phe Val Asp
                  20                  25                  30

 Glu Tyr Asp Pro Thr Ile Glu Asp Ser Tyr Arg Lys Gln Val Val
                  35                  40                  45

 Ile Asp Gly Glu Thr Cys Leu Leu Asp Ile Leu Asp Thr Ala Gly
                  50                  55                  60

 Gln Glu Glu Tyr Ser Ala Met Arg Asp Gln Tyr Met Arg Thr Gly
                  65                  70                  75

 Glu Gly Phe Leu Cys Val Phe Ala Ile Asn Asn Thr Lys Ser Phe
                  80                  85                  90

 Glu Asp Ile His His Tyr Arg Glu Gln Ile Lys Arg Val Lys Asp
                  95                 100                 105

 Ser Glu Asp Val Pro Met Val Leu Val Gly Asn Lys Cys Asp Leu
                 110                 115                 120

 Pro Ser Arg Thr Val Asp Thr Lys Gln Ala Gln Asp Leu Ala Arg
                 125                 130                 135

 Ser Tyr Gly Ile Pro Phe Ile Glu Thr Ser Ala Lys Thr Arg Gln
                 140                 145                 150

 Gly Val Asp Asp Ala Phe Tyr Thr Leu Val Arg Glu Ile Arg Lys
                 155                 160                 165

 His Lys Glu Lys Met Ser Lys Asp Gly Lys Lys Lys Lys Lys Lys
                 170                 175                 180

 Ser Lys Thr Lys Cys Val Ile Met
                 185

<210> 5643
<211> 1586
<212> DNA
<213> Homo sapien

<400> 5643
 gaggacaggt ttgtgcgctg gacgcaagca ccaggcgcag cctcgctcgc 50

 cgacacccgg ccagaacgtg ttacgagtca gtttttagtg aaaaaacatt 100

 gagctaggag ccaagaccca tctcttcact attttggtat tgtgcaagtc 150

 atcttacctc tctggatctc agttgtctca tctgtaaaaa ggagataaaa 200

 attatttacc tgcctgaaca tgaggtggag gaccatcctg ctacagtatt 250

 gctttctctt gattacatgt ttacttactg ctcttgaagc tgtgcctatt 300

 gacatagaca agacaaaagt acaaaatatt caccctgtgg aaagtgcgaa 350

 gatagaacca ccagatactg gactttatta tgatgaatat ctcaagcaag 400

 tgattgatgt gctggaaaca gataaacact tcagagaaaa gctccagaaa 450

 gcagacatag aggaaataaa gagtgggagg ctaagcaaag aactggattt 500

 agtaagtcac catgtgagga caaaacttga tgaactgaaa aggcaagaag 550

 taggaaggtt aagaatgtta attaaagcta agttggattc ccttcaagat 600

 ataggcatgg accaccaagc tcttctaaaa caatttgatc acctaaacca 650

 cctgaatcct gacaagtttg aatccacaga tttagatatg ctaatcaaag 700

 cggcaacaag tgatctggaa cactatgaca agactcgtca tgaagaattt 750

 aaaaaatatg aaatgatgaa ggaacatgaa aggagagaat atttaaaaac 800

 attgaatgaa gaaaagagaa aagaagaaga gtctaaattt gaagaaatga 850

 agaaaaagca tgaaaatcac cctaaagtta atcacccagg aagcaaagat 900

 caactaaaag aggtatggga agagactgat ggattggatc ctaatgactt 950

 tgaccccaag acatttttca aattacatga tgtcaatagt gatggattcc 1000

 tggatgaaca agaattagaa gccctattta ctaaagagtt ggagaaagta 1050

 tatgacccta aaaatgaaga ggatgatatg gtagaaatgg aagaagaaag 1100

 gcttagaatg agggaacatg taatgaatga ggttgatact aacaaagaca 1150

 gattggtgac tctggaggag tttttgaaag ccacagaaaa aaaagaattc 1200

 ttggagccag atagctggga gacattagat cagcaacagt tcttcacaga 1250

 ggaagaacta aaagaatatg aaaatattat tgctttacaa gaaaatgaac 1300

 ttaagaagaa ggcagatgag cttcagaaac aaaaagaaga gctacaacgt 1350

 cagcatgatc aactggaggc tcagaagctg gaatatcatc aggtcataca 1400

 gcagatggaa caaaaaaaat tacaacaagg aattcctcca tcagggccag 1450

 ctggagaatt gaagtttgag ccacacattt aaagtctgaa gtccaccaga 1500

 acttggaaga aagctgttaa ctcaacatct atttcatctt tttagctccc 1550

 ttcccttttc tctgctcaat aaatatttta aaagca 1586

<210> 5644
<211> 420
<212> PRT
<213> Homo sapien

<400> 5644
 Met Arg Trp Arg Thr Ile Leu Leu Gln Tyr Cys Phe Leu Leu Ile
   1               5                  10                  15

 Thr Cys Leu Leu Thr Ala Leu Glu Ala Val Pro Ile Asp Ile Asp
                  20                  25                  30

 Lys Thr Lys Val Gln Asn Ile His Pro Val Glu Ser Ala Lys Ile
                  35                  40                  45

 Glu Pro Pro Asp Thr Gly Leu Tyr Tyr Asp Glu Tyr Leu Lys Gln
                  50                  55                  60

 Val Ile Asp Val Leu Glu Thr Asp Lys His Phe Arg Glu Lys Leu
                  65                  70                  75

 Gln Lys Ala Asp Ile Glu Glu Ile Lys Ser Gly Arg Leu Ser Lys
                  80                  85                  90

 Glu Leu Asp Leu Val Ser His His Val Arg Thr Lys Leu Asp Glu
                  95                 100                 105

 Leu Lys Arg Gln Glu Val Gly Arg Leu Arg Met Leu Ile Lys Ala
                 110                 115                 120

 Lys Leu Asp Ser Leu Gln Asp Ile Gly Met Asp His Gln Ala Leu
                 125                 130                 135

 Leu Lys Gln Phe Asp His Leu Asn His Leu Asn Pro Asp Lys Phe
                 140                 145                 150

 Glu Ser Thr Asp Leu Asp Met Leu Ile Lys Ala Ala Thr Ser Asp
                 155                 160                 165

 Leu Glu His Tyr Asp Lys Thr Arg His Glu Glu Phe Lys Lys Tyr
                 170                 175                 180

 Glu Met Met Lys Glu His Glu Arg Arg Glu Tyr Leu Lys Thr Leu
                 185                 190                 195

 Asn Glu Glu Lys Arg Lys Glu Glu Glu Ser Lys Phe Glu Glu Met
                 200                 205                 210

 Lys Lys Lys His Glu Asn His Pro Lys Val Asn His Pro Gly Ser
                 215                 220                 225

 Lys Asp Gln Leu Lys Glu Val Trp Glu Glu Thr Asp Gly Leu Asp
                 230                 235                 240

 Pro Asn Asp Phe Asp Pro Lys Thr Phe Phe Lys Leu His Asp Val
                 245                 250                 255

 Asn Ser Asp Gly Phe Leu Asp Glu Gln Glu Leu Glu Ala Leu Phe
                 260                 265                 270

 Thr Lys Glu Leu Glu Lys Val Tyr Asp Pro Lys Asn Glu Glu Asp
                 275                 280                 285

 Asp Met Val Glu Met Glu Glu Glu Arg Leu Arg Met Arg Glu His
                 290                 295                 300

 Val Met Asn Glu Val Asp Thr Asn Lys Asp Arg Leu Val Thr Leu
                 305                 310                 315

 Glu Glu Phe Leu Lys Ala Thr Glu Lys Lys Glu Phe Leu Glu Pro
                 320                 325                 330

 Asp Ser Trp Glu Thr Leu Asp Gln Gln Gln Phe Phe Thr Glu Glu
                 335                 340                 345

 Glu Leu Lys Glu Tyr Glu Asn Ile Ile Ala Leu Gln Glu Asn Glu
                 350                 355                 360

 Leu Lys Lys Lys Ala Asp Glu Leu Gln Lys Gln Lys Glu Glu Leu
                 365                 370                 375

 Gln Arg Gln His Asp Gln Leu Glu Ala Gln Lys Leu Glu Tyr His
                 380                 385                 390

 Gln Val Ile Gln Gln Met Glu Gln Lys Lys Leu Gln Gln Gly Ile
                 395                 400                 405

 Pro Pro Ser Gly Pro Ala Gly Glu Leu Lys Phe Glu Pro His Ile
                 410                 415                 420

<210> 5645
<211> 1542
<212> DNA
<213> Homo sapien

<400> 5645
 cgaccggcac gttcacccca tccctcaggc tttatttatt ttttttcgac 50

 aggttctttt caaggctcca gtcaccgcag cagttgtcca tgctgtagtt 100

 tccactttcc tgtatgggcg ggctggttag gattccactt tcccccaagt 150

 gcttagccca gggccagaca aaaagtagtt gcttaagaaa tacttgttga 200

 aggaataaat taatgaatga atttgtgctt acagcggctg gatggcagac 250

 aaacctatga ttataggaac atcaggatct catttggaac agattacgga 300

 tgctgcattg tggaacttgg aaaaacaaga gttcttggac aggtttcctg 350

 tgaacttgtg tctccaaaac tcaatcgggc aacagaaggt attctttttt 400

 taaccttgaa ctctctcaga tggccgctcc agctttcgaa cctggcaggc 450

 agtcagatct cttggtgaag ttgaatcgac tcatggaaag atgtctaaga 500

 aattcgaagt gtatagacac tgagtctctc tgtgttgttg ctggtgaaaa 550

 ggtttggcaa atacgtgtag acctacattt attaaatcat gatggaaata 600

 ttattgatgc tgccagcatt gctgcaatcg tggccttatg tcatttccga 650

 agacctgatg tctctgtcca aggagatgaa gtaacactgt atacacctga 700

 agagcgtgat cctgtaccat taagtatcca ccacatgccc atttgtgtca 750

 gttttgcctt tttccagcaa ggaacatatt tattggtgga tcccaatgaa 800

 cgagaagaac gtgtgatgga tggcttgctg gtgattgcca tgaacaaaca 850

 tcgagagatt tgtactatcc agtccagtgg tgggataatg ctactaaaag 900

 atcaagttct gagatgcagt aaaatcgctg gtgtgaaagt agcagaaatt 950

 acagagctaa tattgaaagc tttggagaat gaccaaaaag taaggaaaga 1000

 aggtggaaag tttggttttg cagagtctat agcaaatcaa aggatcacag 1050

 catttaaaat ggaaaaggcc cctattgata cctcggatgt agaagaaaaa 1100

 gcagaagaaa tcattgctga agcagaacct ccttcagaag ttgtttctac 1150

 acctgtgcta tggactcctg gaactgccca aattggagag ggagtagaaa 1200

 actcctgggg tgatcttgaa gactctgaga aggaagatga tgaaggcggt 1250

 ggtgatcaag ctatcattct tgatggtata aaaatggaca ctggagtaga 1300

 agtctctgat attggaagcc aagatgctcc cataatactc tcagatagtg 1350

 aagaagaaga aatgatcatt ttggaaccag acaagaatcc aaagaaaata 1400

 agaacacaga ccaccagtgc aaaacaagaa aaagcaccaa gtaaaaagcc 1450

 agtgaaaaga agaaaaaaga agagagctgc caattaaagc taacagttgt 1500

 atatctgtat atataactat taaaagggat atttattcca tt 1542

<210> 5646
<211> 355
<212> PRT
<213> Homo sapien

<400> 5646
 Met Ala Ala Pro Ala Phe Glu Pro Gly Arg Gln Ser Asp Leu Leu
   1               5                  10                  15

 Val Lys Leu Asn Arg Leu Met Glu Arg Cys Leu Arg Asn Ser Lys
                  20                  25                  30

 Cys Ile Asp Thr Glu Ser Leu Cys Val Val Ala Gly Glu Lys Val
                  35                  40                  45

 Trp Gln Ile Arg Val Asp Leu His Leu Leu Asn His Asp Gly Asn
                  50                  55                  60

 Ile Ile Asp Ala Ala Ser Ile Ala Ala Ile Val Ala Leu Cys His
                  65                  70                  75

 Phe Arg Arg Pro Asp Val Ser Val Gln Gly Asp Glu Val Thr Leu
                  80                  85                  90

 Tyr Thr Pro Glu Glu Arg Asp Pro Val Pro Leu Ser Ile His His
                  95                 100                 105

 Met Pro Ile Cys Val Ser Phe Ala Phe Phe Gln Gln Gly Thr Tyr
                 110                 115                 120

 Leu Leu Val Asp Pro Asn Glu Arg Glu Glu Arg Val Met Asp Gly
                 125                 130                 135

 Leu Leu Val Ile Ala Met Asn Lys His Arg Glu Ile Cys Thr Ile
                 140                 145                 150

 Gln Ser Ser Gly Gly Ile Met Leu Leu Lys Asp Gln Val Leu Arg
                 155                 160                 165

 Cys Ser Lys Ile Ala Gly Val Lys Val Ala Glu Ile Thr Glu Leu
                 170                 175                 180

 Ile Leu Lys Ala Leu Glu Asn Asp Gln Lys Val Arg Lys Glu Gly
                 185                 190                 195

 Gly Lys Phe Gly Phe Ala Glu Ser Ile Ala Asn Gln Arg Ile Thr
                 200                 205                 210

 Ala Phe Lys Met Glu Lys Ala Pro Ile Asp Thr Ser Asp Val Glu
                 215                 220                 225

 Glu Lys Ala Glu Glu Ile Ile Ala Glu Ala Glu Pro Pro Ser Glu
                 230                 235                 240

 Val Val Ser Thr Pro Val Leu Trp Thr Pro Gly Thr Ala Gln Ile
                 245                 250                 255

 Gly Glu Gly Val Glu Asn Ser Trp Gly Asp Leu Glu Asp Ser Glu
                 260                 265                 270

 Lys Glu Asp Asp Glu Gly Gly Gly Asp Gln Ala Ile Ile Leu Asp
                 275                 280                 285

 Gly Ile Lys Met Asp Thr Gly Val Glu Val Ser Asp Ile Gly Ser
                 290                 295                 300

 Gln Asp Ala Pro Ile Ile Leu Ser Asp Ser Glu Glu Glu Glu Met
                 305                 310                 315

 Ile Ile Leu Glu Pro Asp Lys Asn Pro Lys Lys Ile Arg Thr Gln
                 320                 325                 330

 Thr Thr Ser Ala Lys Gln Glu Lys Ala Pro Ser Lys Lys Pro Val
                 335                 340                 345

 Lys Arg Arg Lys Lys Lys Arg Ala Ala Asn
                 350                 355

<210> 5647
<211> 759
<212> DNA
<213> Homo sapien

<400> 5647
 ctgtgctgta aaaacaagag taacattttt atattaaagt taaataaagt 50

 tacaactttg aagagagttt ctgcaagaca tgacacaaag ctgctagcag 100

 aaaatcaaaa cgctgattaa aagaagcacg gtatgatgac caaacataaa 150

 aagtgtttta taattgttgg tgttttaata acaactaata ttattactct 200

 gatagttaaa ctaactcgag attctcagag tttatgcccc tatgattgga 250

 ttggtttcca aaacaaatgc tattatttct ctaaagaaga aggagattgg 300

 aattcaagta aatacaactg ttccactcaa catgccgacc taactataat 350

 tgacaacata gaagaaatga attttcttag gcggtataaa tgcagttctg 400

 atcactggat tggactgaag atggcaaaaa atcgaacagg acaatgggta 450

 catggagcta catttaccaa atcgtttggc atgagaggga gtgaaggatg 500

 tgcctacctc agcgatgatg gtgcagcaac agctagatgt tacaccgaaa 550

 gaaaatggat ttgcaggaaa agaatacact aagttaatgt ctaagataat 600

 ggggaaaata gaaaataaca ttattaagtg taaaaccagc aaagtacttt 650

 tttaattaaa caaagttcga gttttgtacc tgtctggtta attctgctta 700

 cgtgtcaggc tacacataaa agccacttca aagattggca aaaaaaaaaa 750

 aaaaaaaaa 759

<210> 5648
<211> 149
<212> PRT
<213> Homo sapien

<400> 5648
 Met Met Thr Lys His Lys Lys Cys Phe Ile Ile Val Gly Val Leu
   1               5                  10                  15

 Ile Thr Thr Asn Ile Ile Thr Leu Ile Val Lys Leu Thr Arg Asp
                  20                  25                  30

 Ser Gln Ser Leu Cys Pro Tyr Asp Trp Ile Gly Phe Gln Asn Lys
                  35                  40                  45

 Cys Tyr Tyr Phe Ser Lys Glu Glu Gly Asp Trp Asn Ser Ser Lys
                  50                  55                  60

 Tyr Asn Cys Ser Thr Gln His Ala Asp Leu Thr Ile Ile Asp Asn
                  65                  70                  75

 Ile Glu Glu Met Asn Phe Leu Arg Arg Tyr Lys Cys Ser Ser Asp
                  80                  85                  90

 His Trp Ile Gly Leu Lys Met Ala Lys Asn Arg Thr Gly Gln Trp
                  95                 100                 105

 Val His Gly Ala Thr Phe Thr Lys Ser Phe Gly Met Arg Gly Ser
                 110                 115                 120

 Glu Gly Cys Ala Tyr Leu Ser Asp Asp Gly Ala Ala Thr Ala Arg
                 125                 130                 135

 Cys Tyr Thr Glu Arg Lys Trp Ile Cys Arg Lys Arg Ile His
                 140                 145

<210> 5649
<211> 836
<212> DNA
<213> Homo sapien

<400> 5649
 ccggtgagtc gccggcgctg cagagggagg cggcactggt ctcgacgtgg 50

 ggcggccagc gatgaagccg cccagttcaa tacaaacaag tgagtttgac 100

 tcatcagatg aagagcctat tgaagatgaa cagactccaa ttcatatatc 150

 atggctatct ttgtcacgag tgaattgttc tcagtttctc ggtttatgtg 200

 ctcttccagg ttgtaaattt aaagatgtta gaagaaatgt ccaaaaagat 250

 acagaagaac taaagagctg tggtatacaa gacatatttg ttttctgcac 300

 cagaggggaa ctgtcaaaat atagagtccc aaaccttctg gatctctacc 350

 agcaatgtgg aattatcacc catcatcatc caatcgcaga tggagggact 400

 cctgacatag ccagctgctg tgaaataatg gaagagctta caacctgcct 450

 taaaaattac cgaaaaacct taatacactg ctatggagga cttgggagat 500

 cttgtcttgt agctgcttgt ctcctactat acctgtctga cacaatatca 550

 ccagagcaag ccatagacag cctgcgagac ctaagaggat ccggggcaat 600

 acagaccatc aagcaataca attatcttca tgagtttcgg gacaaattag 650

 ctgcacatct atcatcaaga gattcacaat caagatctgt atcaagataa 700

 aggaattcaa atagcatata tatgaccatg tctgaaatgt cagttctcta 750

 gcataatttg tattgaaatg aaaccaccag tgttatcaac ttgaatgtaa 800

 atgtacatgt gcagatattc ctaaagtttt attgac 836

<210> 5650
<211> 212
<212> PRT
<213> Homo sapien

<400> 5650
 Met Lys Pro Pro Ser Ser Ile Gln Thr Ser Glu Phe Asp Ser Ser
   1               5                  10                  15

 Asp Glu Glu Pro Ile Glu Asp Glu Gln Thr Pro Ile His Ile Ser
                  20                  25                  30

 Trp Leu Ser Leu Ser Arg Val Asn Cys Ser Gln Phe Leu Gly Leu
                  35                  40                  45

 Cys Ala Leu Pro Gly Cys Lys Phe Lys Asp Val Arg Arg Asn Val
                  50                  55                  60

 Gln Lys Asp Thr Glu Glu Leu Lys Ser Cys Gly Ile Gln Asp Ile
                  65                  70                  75

 Phe Val Phe Cys Thr Arg Gly Glu Leu Ser Lys Tyr Arg Val Pro
                  80                  85                  90

 Asn Leu Leu Asp Leu Tyr Gln Gln Cys Gly Ile Ile Thr His His
                  95                 100                 105

 His Pro Ile Ala Asp Gly Gly Thr Pro Asp Ile Ala Ser Cys Cys
                 110                 115                 120

 Glu Ile Met Glu Glu Leu Thr Thr Cys Leu Lys Asn Tyr Arg Lys
                 125                 130                 135

 Thr Leu Ile His Cys Tyr Gly Gly Leu Gly Arg Ser Cys Leu Val
                 140                 145                 150

 Ala Ala Cys Leu Leu Leu Tyr Leu Ser Asp Thr Ile Ser Pro Glu
                 155                 160                 165

 Gln Ala Ile Asp Ser Leu Arg Asp Leu Arg Gly Ser Gly Ala Ile
                 170                 175                 180

 Gln Thr Ile Lys Gln Tyr Asn Tyr Leu His Glu Phe Arg Asp Lys
                 185                 190                 195

 Leu Ala Ala His Leu Ser Ser Arg Asp Ser Gln Ser Arg Ser Val
                 200                 205                 210

 Ser Arg


<210> 5651
<211> 3096
<212> DNA
<213> Homo sapien

<400> 5651
 cgggcgccca gagggcaaat gaggggcggc ggggtggcgg gtcgggggga 50

 gacgcggaat ttcccagcgc gggggctctg gcttaccctg caaccgggca 100

 gtctctttct gtttacggag agaaagggga aatggaaaag tcggggaggc 150

 ggtggctggc gtccgctgcg ccgcccctgg gcaggctcag acgccgtgag 200

 tcaggggcag agcagggcgg tctgagcgtg cgggcgacgc gggtctcact 250

 cgtccgctcc gctctggact gcgcgccacg ctctggggtc cggcgccctg 300

 gttcctgctt ctgccgctgc cgccgccgga tcccagtggc ccggcgtgct 350

 cggctcccac aggcctgcag ccagcatcgc accgaacctt cggggggccg 400

 cggctggagc gctcggccgg cgtgggagcg ccaaggccgc agatgcaatc 450

 ttcttaccgc gaagaagcca ggggaatagg tagccacatc ttgtttgcag 500

 ataagaaagg aagctaacgc agtatctgca aagccaggag tctgactcag 550

 tacttttctc actcatgcat acaaagcagc taaaaatgac acagcttatt 600

 taccatgccc ctgacactgc actgagcact ttatgagctt gaactctgtt 650

 aatcctcacg accacctcat gagactctcc agaaagagca acagtaatgg 700

 agtacatgag cactggaagt gacaataaag aagagattga tttattaatt 750

 aaacatttaa atgtgtctga tgtaatagac attatggaaa atctttatgc 800

 aagtgaagag ccagcagttt atgaacccag tctaatgacc atgtgtcaag 850

 acagtaatca aaacgatgag cgttctaagt ctctgctgct tagtggccaa 900

 gaggtaccat ggttgtcatc agtcagatat ggaactgtgg aggatttgct 950

 tgcttttgca aaccatatat ccaacactgc aaagcatttt tatggacaac 1000

 gaccacagga atctggaatt ttattaaaca tggtcatcac tccccaaaat 1050

 ggacgttacc aaatagattc cgatgttctc ctgatcccct ggaagctgac 1100

 ttacaggaat attggttctg attttattcc tcggggcgcc tttggaaagg 1150

 tatacttggc acaagatata aagacgaaga aaagaatggc gtgtaaactg 1200

 atcccagtag atcaatttaa gccatctgat gtggaaatcc aggcttgctt 1250

 ccggcacgag aacatcgcag agctgtatgg cgcagtcctg tggggtgaaa 1300

 ctgtccatct ctttatggaa gcaggcgagg gagggtctgt tctggagaaa 1350

 ctggagagct gtggaccaat gagagaattt gaaattattt gggtgacaaa 1400

 gcatgttctc aagggacttg attttctaca ctcaaagaaa gtgatccatc 1450

 atgatattaa acctagcaac attgttttca tgtccacaaa agctgttttg 1500

 gtggattttg gcctaagtgt tcaaatgacc gaagatgtct attttcctaa 1550

 ggacctccga ggaacagaga tttacatgag cccagaggtc atcctgtgca 1600

 ggggccattc aaccaaagca gacatctaca gcctgggggc cacgctcatc 1650

 cacatgcaga cgggcacccc accctgggtg aagcgctacc ctcgctcagc 1700

 ctatccctcc tacctgtaca taatccacaa gcaagcacct ccactggaag 1750

 acattgcaga tgactgcagt ccagggatga gagagctgat agaagcttcc 1800

 ctggagagaa accccaatca ccgcccaaga gccgcagacc tactaaaaca 1850

 tgaggccctg aacccgccca gagaggatca gccacgctgt cagagtctgg 1900

 actctgccct cttggagcgc aagaggctgc tgagtaggaa ggagctggaa 1950

 cttcctgaga acattgctga ttcttcgtgc acaggaagca ccgaggaatc 2000

 tgagatgctc aagaggcaac gctctctcta catcgacctc ggcgctctgg 2050

 ctggctactt caatcttgtt cggggaccac caacgcttga atatggctga 2100

 aggatgccat gtttgctcta aattaagaca gcattgatct cctggaggct 2150

 ggttctgctg cctctacaca ggggccctgt acagtgaatg gtgccatttt 2200

 cgaaggagca gtgtgacctc ctgtgaccca tgaatgtgcc tccaagcggc 2250

 cctgtgtgtt tgacatgtga agctatttga tatgcaccag gtctcaaggt 2300

 tctcatttct caggtgacgt gattctaagg caggaatttg agagttcaca 2350

 gaaggatcgt gtctgctgac tgtttcattc actgtgcact ttgctcaaaa 2400

 ttttaaaaat accaatcaca aggataatag agtagcctaa aattactatt 2450

 cttggttctt atttaagtat ggaatattca ttttactcag aatagctgtt 2500

 ttgtgtatat tggtgtatat tatataactc tttgagcctt tattggtaaa 2550

 ttctggtata cattgaattc attataattt gggtgactag aacaacttga 2600

 agattgtagc aataagctgg actagtgtcc taaaaatggc taactgatga 2650

 attagaagcc atctgacagc aggccactag tgacagtttc ttttgtgttc 2700

 ctatggaaac attttatact gtacatgcta tgctgaagac attcaaaacg 2750

 tgatgttttg aatgtggata aaactgtgta aaccacataa tttttgtaca 2800

 tcccaaagga tgagaatgtg acctttaaga aaaatgaaaa cttttgtaaa 2850

 ttattgatga ttttgtaatt cttatgacta aattttcttt taagcatttg 2900

 tatattaaaa tagcatactg tgtatgtttt atatcaaatg ccttcatgaa 2950

 tctttcatac atatatatat ttgtaacatt gtaaagtatg tgagtagtct 3000

 tatgtaaagt atgtttttac attatgcaaa taaaacccaa tacttttgtc 3050

 caatgtggtt ggtcaaatca actgaataaa ttcagtattt tgcctt 3096

<210> 5652
<211> 467
<212> PRT
<213> Homo sapien

<400> 5652
 Met Glu Tyr Met Ser Thr Gly Ser Asp Asn Lys Glu Glu Ile Asp
   1               5                  10                  15

 Leu Leu Ile Lys His Leu Asn Val Ser Asp Val Ile Asp Ile Met
                  20                  25                  30

 Glu Asn Leu Tyr Ala Ser Glu Glu Pro Ala Val Tyr Glu Pro Ser
                  35                  40                  45

 Leu Met Thr Met Cys Gln Asp Ser Asn Gln Asn Asp Glu Arg Ser
                  50                  55                  60

 Lys Ser Leu Leu Leu Ser Gly Gln Glu Val Pro Trp Leu Ser Ser
                  65                  70                  75

 Val Arg Tyr Gly Thr Val Glu Asp Leu Leu Ala Phe Ala Asn His
                  80                  85                  90

 Ile Ser Asn Thr Ala Lys His Phe Tyr Gly Gln Arg Pro Gln Glu
                  95                 100                 105

 Ser Gly Ile Leu Leu Asn Met Val Ile Thr Pro Gln Asn Gly Arg
                 110                 115                 120

 Tyr Gln Ile Asp Ser Asp Val Leu Leu Ile Pro Trp Lys Leu Thr
                 125                 130                 135

 Tyr Arg Asn Ile Gly Ser Asp Phe Ile Pro Arg Gly Ala Phe Gly
                 140                 145                 150

 Lys Val Tyr Leu Ala Gln Asp Ile Lys Thr Lys Lys Arg Met Ala
                 155                 160                 165

 Cys Lys Leu Ile Pro Val Asp Gln Phe Lys Pro Ser Asp Val Glu
                 170                 175                 180

 Ile Gln Ala Cys Phe Arg His Glu Asn Ile Ala Glu Leu Tyr Gly
                 185                 190                 195

 Ala Val Leu Trp Gly Glu Thr Val His Leu Phe Met Glu Ala Gly
                 200                 205                 210

 Glu Gly Gly Ser Val Leu Glu Lys Leu Glu Ser Cys Gly Pro Met
                 215                 220                 225

 Arg Glu Phe Glu Ile Ile Trp Val Thr Lys His Val Leu Lys Gly
                 230                 235                 240

 Leu Asp Phe Leu His Ser Lys Lys Val Ile His His Asp Ile Lys
                 245                 250                 255

 Pro Ser Asn Ile Val Phe Met Ser Thr Lys Ala Val Leu Val Asp
                 260                 265                 270

 Phe Gly Leu Ser Val Gln Met Thr Glu Asp Val Tyr Phe Pro Lys
                 275                 280                 285

 Asp Leu Arg Gly Thr Glu Ile Tyr Met Ser Pro Glu Val Ile Leu
                 290                 295                 300

 Cys Arg Gly His Ser Thr Lys Ala Asp Ile Tyr Ser Leu Gly Ala
                 305                 310                 315

 Thr Leu Ile His Met Gln Thr Gly Thr Pro Pro Trp Val Lys Arg
                 320                 325                 330

 Tyr Pro Arg Ser Ala Tyr Pro Ser Tyr Leu Tyr Ile Ile His Lys
                 335                 340                 345

 Gln Ala Pro Pro Leu Glu Asp Ile Ala Asp Asp Cys Ser Pro Gly
                 350                 355                 360

 Met Arg Glu Leu Ile Glu Ala Ser Leu Glu Arg Asn Pro Asn His
                 365                 370                 375

 Arg Pro Arg Ala Ala Asp Leu Leu Lys His Glu Ala Leu Asn Pro
                 380                 385                 390

 Pro Arg Glu Asp Gln Pro Arg Cys Gln Ser Leu Asp Ser Ala Leu
                 395                 400                 405

 Leu Glu Arg Lys Arg Leu Leu Ser Arg Lys Glu Leu Glu Leu Pro
                 410                 415                 420

 Glu Asn Ile Ala Asp Ser Ser Cys Thr Gly Ser Thr Glu Glu Ser
                 425                 430                 435

 Glu Met Leu Lys Arg Gln Arg Ser Leu Tyr Ile Asp Leu Gly Ala
                 440                 445                 450

 Leu Ala Gly Tyr Phe Asn Leu Val Arg Gly Pro Pro Thr Leu Glu
                 455                 460                 465

 Tyr Gly


<210> 5653
<211> 672
<212> DNA
<213> Homo sapien

<400> 5653
 atggcttgcc ttggatttca gcggcacaag gctcagctga acctggctgc 50

 caggacctgg ccctgcactc tcctgttttt tcttctcttc atccctgtct 100

 tctgcaaagc aatgcacgtg gcccagcctg ctgtggtact ggccagcagc 150

 cgaggcatcg ccagctttgt gtgtgagtat gcatctccag gcaaagccac 200

 tgaggtccgg gtgacagtgc ttcggcaggc tgacagccag gtgactgaag 250

 tctgtgcggc aacctacatg acggggaatg agttgacctt cctagatgat 300

 tccatctgca cgggcacctc cagtggaaat caagtgaacc tcactatcca 350

 aggactgagg gccatggaca cgggactcta catctgcaag gtggagctca 400

 tgtacccacc gccatactac ctgggcatag gcaacggaac ccagatttat 450

 gtaattgatc cagaaccgtg cccagattct gacttcctcc tctggatcct 500

 tgcagcagtt agttcggggt tgttttttta tagctttctc ctcacagctg 550

 tttctttgag caaaatgcta aagaaaagaa gccctcttac aacaggggtc 600

 tatgtgaaaa tgcccccaac agagccagaa tgtgaaaagc aatttcagcc 650

 ttattttatt cccatcaatt ga 672

<210> 5654
<211> 223
<212> PRT
<213> Homo sapien

<400> 5654
 Met Ala Cys Leu Gly Phe Gln Arg His Lys Ala Gln Leu Asn Leu
   1               5                  10                  15

 Ala Ala Arg Thr Trp Pro Cys Thr Leu Leu Phe Phe Leu Leu Phe
                  20                  25                  30

 Ile Pro Val Phe Cys Lys Ala Met His Val Ala Gln Pro Ala Val
                  35                  40                  45

 Val Leu Ala Ser Ser Arg Gly Ile Ala Ser Phe Val Cys Glu Tyr
                  50                  55                  60

 Ala Ser Pro Gly Lys Ala Thr Glu Val Arg Val Thr Val Leu Arg
                  65                  70                  75

 Gln Ala Asp Ser Gln Val Thr Glu Val Cys Ala Ala Thr Tyr Met
                  80                  85                  90

 Thr Gly Asn Glu Leu Thr Phe Leu Asp Asp Ser Ile Cys Thr Gly
                  95                 100                 105

 Thr Ser Ser Gly Asn Gln Val Asn Leu Thr Ile Gln Gly Leu Arg
                 110                 115                 120

 Ala Met Asp Thr Gly Leu Tyr Ile Cys Lys Val Glu Leu Met Tyr
                 125                 130                 135

 Pro Pro Pro Tyr Tyr Leu Gly Ile Gly Asn Gly Thr Gln Ile Tyr
                 140                 145                 150

 Val Ile Asp Pro Glu Pro Cys Pro Asp Ser Asp Phe Leu Leu Trp
                 155                 160                 165

 Ile Leu Ala Ala Val Ser Ser Gly Leu Phe Phe Tyr Ser Phe Leu
                 170                 175                 180

 Leu Thr Ala Val Ser Leu Ser Lys Met Leu Lys Lys Arg Ser Pro
                 185                 190                 195

 Leu Thr Thr Gly Val Tyr Val Lys Met Pro Pro Thr Glu Pro Glu
                 200                 205                 210

 Cys Glu Lys Gln Phe Gln Pro Tyr Phe Ile Pro Ile Asn
                 215                 220

<210> 5655
<211> 2084
<212> DNA
<213> Mus musculus

<400> 5655
 aaccgcatct gcagcgagca actgagaagc caagactgag ccggcggccg 50

 cggcgcagcg aacgagcagt gaccgtgctc ctacccagct ctgcttcaca 100

 gcgcccacct gtctccgccc ctcggcccct cgcccggctt tgcctaaccg 150

 ccacgatgat gttctcgggc ttcaacgcag actacgaggc gtcatcctcc 200

 cgctgcagca gcgcgtcccc ggccggggat agcctctctt actaccactc 250

 acccgcagac tccttctcca gcatgggctc gcctgtcaac gcgcaggact 300

 tctgcacgga cctggccgtc tccagtgcca acttcattcc cacggtcact 350

 gccatctcga ccagtccgga cctgcagtgg ctggtgcagc ccgccctcgt 400

 ctcctctgtg gccccatcgc agaccagagc ccctcaccct ttcggagtcc 450

 ccgccccctc cgctggggct tactccaggg ctggcgttgt gaagaccatg 500

 acaggaggcc gagcgcagag cattggcagg aggggcaagg tggaacagtt 550

 atctccagaa gaagaagaga aaaggagaat ccgaagggaa aggaataaga 600

 tggctgcagc caaatgccgc aaccggagga gggagctgac tgatacactc 650

 caagcggaga cagaccaact agaagatgag aagtctgctt tgcagaccga 700

 gattgccaac ctgctgaagg agaaggaaaa actagagttc atcctggcag 750

 ctcaccgacc tgcctgcaag atccctgatg acctgggctt cccagaagag 800

 atgtctgtgg cttcccttga tctgactggg ggcctgccag aggttgccac 850

 cccggagtct gaggaggcct tcaccctgcc tctcctcaat gaccctgagc 900

 ccaagccctc agtggaacct gtcaagagca tcagcagcat ggagctgaag 950

 accgagccct ttgatgactt cctgttccca gcatcatcca ggcccagtgg 1000

 ctctgagaca gcccgctccg tgccagacat ggacctatct gggtccttct 1050

 atgcagcaga ctgggagcct ctgcacagtg gctccctggg gatggggccc 1100

 atggccacag agctggagcc cctgtgcact ccggtggtca cctgtactcc 1150

 cagctgcact gcttacacgt cttccttcgt cttcacctac cccgaggctg 1200

 actccttccc cagctgtgca gctgcccacc gcaagggcag cagcagcaat 1250

 gagccttcct ctgactcgct cagctcaccc acgctgctgg ccctgtgagg 1300

 gggcagggaa ggggaggcag ccggcaccca caagtgccac tgcccgagct 1350

 ggtgcattac agagaggaga aacacatctt ccctagaggg ttcctgtaga 1400

 cctagggagg accttatctg tgcgtgaaac acaccaggct gtgggcctca 1450

 aggacttgaa agcatccatg tgtggactca agtccttacc tcttccggag 1500

 atgtagcaaa acgcatggag tgtgtattgt tcccagtgac acttcagaga 1550

 gctggtagtt agtagcatgt tgagccaggc ctgggtctgt gtctcttttc 1600

 tctttctcct tagtcttctc atagcattaa ctaatctatt gggttcatta 1650

 ttggaattaa cctggtgctg gatattttca aattgtatct agtgcagctg 1700

 attttaacaa taactactgt gttcctggca atagtgtgtt ctgattagaa 1750

 atgaccaata ttatactaag aaaagatacg actttatttt ctggtagata 1800

 gaaataaata gctatatcca tgtactgtag tttttcttca acatcaatgt 1850

 tcattgtaat gttactgatc atgcattgtt gaggtggtct gaatgttctg 1900

 acattaacag ttttccatga aaacgtttta ttgtgttttt aatttattta 1950

 ttaagatgga ttctcagata tttatatttt tattttattt ttttctacct 2000

 tgaggtcttt tgacatgtgg aaagtgaatt tgaatgaaaa atttaagcat 2050

 tgtttgctta ttgttccaag acattgtcaa taaa 2084

<210> 5656
<211> 380
<212> PRT
<213> Mus musculus

<400> 5656
 Met Met Phe Ser Gly Phe Asn Ala Asp Tyr Glu Ala Ser Ser Ser
   1               5                  10                  15

 Arg Cys Ser Ser Ala Ser Pro Ala Gly Asp Ser Leu Ser Tyr Tyr
                  20                  25                  30

 His Ser Pro Ala Asp Ser Phe Ser Ser Met Gly Ser Pro Val Asn
                  35                  40                  45

 Ala Gln Asp Phe Cys Thr Asp Leu Ala Val Ser Ser Ala Asn Phe
                  50                  55                  60

 Ile Pro Thr Val Thr Ala Ile Ser Thr Ser Pro Asp Leu Gln Trp
                  65                  70                  75

 Leu Val Gln Pro Ala Leu Val Ser Ser Val Ala Pro Ser Gln Thr
                  80                  85                  90

 Arg Ala Pro His Pro Phe Gly Val Pro Ala Pro Ser Ala Gly Ala
                  95                 100                 105

 Tyr Ser Arg Ala Gly Val Val Lys Thr Met Thr Gly Gly Arg Ala
                 110                 115                 120

 Gln Ser Ile Gly Arg Arg Gly Lys Val Glu Gln Leu Ser Pro Glu
                 125                 130                 135

 Glu Glu Glu Lys Arg Arg Ile Arg Arg Glu Arg Asn Lys Met Ala
                 140                 145                 150

 Ala Ala Lys Cys Arg Asn Arg Arg Arg Glu Leu Thr Asp Thr Leu
                 155                 160                 165

 Gln Ala Glu Thr Asp Gln Leu Glu Asp Glu Lys Ser Ala Leu Gln
                 170                 175                 180

 Thr Glu Ile Ala Asn Leu Leu Lys Glu Lys Glu Lys Leu Glu Phe
                 185                 190                 195

 Ile Leu Ala Ala His Arg Pro Ala Cys Lys Ile Pro Asp Asp Leu
                 200                 205                 210

 Gly Phe Pro Glu Glu Met Ser Val Ala Ser Leu Asp Leu Thr Gly
                 215                 220                 225

 Gly Leu Pro Glu Val Ala Thr Pro Glu Ser Glu Glu Ala Phe Thr
                 230                 235                 240

 Leu Pro Leu Leu Asn Asp Pro Glu Pro Lys Pro Ser Val Glu Pro
                 245                 250                 255

 Val Lys Ser Ile Ser Ser Met Glu Leu Lys Thr Glu Pro Phe Asp
                 260                 265                 270

 Asp Phe Leu Phe Pro Ala Ser Ser Arg Pro Ser Gly Ser Glu Thr
                 275                 280                 285

 Ala Arg Ser Val Pro Asp Met Asp Leu Ser Gly Ser Phe Tyr Ala
                 290                 295                 300

 Ala Asp Trp Glu Pro Leu His Ser Gly Ser Leu Gly Met Gly Pro
                 305                 310                 315

 Met Ala Thr Glu Leu Glu Pro Leu Cys Thr Pro Val Val Thr Cys
                 320                 325                 330

 Thr Pro Ser Cys Thr Ala Tyr Thr Ser Ser Phe Val Phe Thr Tyr
                 335                 340                 345

 Pro Glu Ala Asp Ser Phe Pro Ser Cys Ala Ala Ala His Arg Lys
                 350                 355                 360

 Gly Ser Ser Ser Asn Glu Pro Ser Ser Asp Ser Leu Ser Ser Pro
                 365                 370                 375

 Thr Leu Leu Ala Leu
                 380

<210> 5657
<211> 2074
<212> DNA
<213> Homo sapien

<400> 5657
 caagcagcgg gttagtggtc gcgcgcccga cctccgcagt cccagccgag 50

 ccgcgaccct tccggccgtc cccaccccac ctcgccgcca tgcgcctccg 100

 ccgcctagcg ctgttcccgg gtgtggcgct gcttcttgcc gcggcccgcc 150

 tcgccgctgc ctccgacgtg ctagaactca cggacgacaa cttcgagagt 200

 cgcatctccg acacgggctc tgcgggcctc atgctcgtcg agttcttcgc 250

 cccctggtgt ggacactgca agagacttgc acctgagtat gaagctgcag 300

 ctaccagatt aaaaggaata gtcccattag caaaggttga ttgcactgcc 350

 aacactaaca cctgtaataa atatggagtc agtggatatc caaccctgaa 400

 gatatttaga gatggtgaag aagcaggtgc ttatgatgga cctaggactg 450

 ctgatggaat tgtcagccac ttgaagaagc aggcaggacc agcttcagtg 500

 cctctcagga ctgaggaaga atttaagaaa ttcattagtg ataaagatgc 550

 ctctatagta ggttttttcg atgattcatt cagtgaggct cactccgagt 600

 tcctaaaagc agccagcaac ttgagggata actaccgatt tgcacatacg 650

 aatgttgagt ctctggtgaa cgagtatgat gataatggag agggtatcat 700

 cttatttcgt ccttcacatc tcactaacaa gtttgaggac aagactgtgg 750

 catatacaga gcaaaaaatg accagtggca aaattaaaaa gtttatccag 800

 gaaaacattt ttggtatctg ccctcacatg acagaagaca ataaagattt 850

 gatacagggc aaggacttac ttattgctta ctatgatgtg gactatgaaa 900

 agaacgctaa aggttccaac tactggagaa acagggtaat gatggtggca 950

 aagaaattcc tggatgctgg gcacaaactc aactttgctg tagctagccg 1000

 caaaaccttt agccatgaac tttctgattt tggcttggag agcactgctg 1050

 gagagattcc tgttgttgct atcagaactg ctaaaggaga gaagtttgtc 1100

 atgcaggagg agttctcgcg tgatgggaag gctctggaga ggttcctgca 1150

 ggattacttt gatggcaatc tgaagagata cctgaagtct gaacctatcc 1200

 cagagagcaa tgatgggcct gtgaaggtag tggtagcaga gaattttgat 1250

 gaaatagtga ataatgaaaa taaagatgtg ctgattgaat tttatgcccc 1300

 ttggtgtggt cactgtaaga acctggagcc caagtataaa gaacttggcg 1350

 agaagctcag caaagaccca aatatcgtca tagccaagat ggatgccaca 1400

 gccaatgatg tgccttctcc atatgaagtc agaggttttc ctaccatata 1450

 cttctctcca gccaacaaga agctaaatcc aaagaaatat gaaggtggcc 1500

 gtgaattaag tgattttatt agctatctac aaagagaagc tacaaacccc 1550

 cctgtaattc aagaagaaaa acccaagaag aagaagaagg cacaggagga 1600

 tctctaaagc agtagccaaa caccactttg taaaaggact cttccatcag 1650

 agatgggaaa accattgggg aggactagga cccatatggg aattattacc 1700

 tctcagggcc gagaggacag aatggatata atctgaatcc tgttaaattt 1750

 tctctaaact gtttcttagc tgcactgttt atggaaatac caggaccagt 1800

 ttatgtttgt ggttttggga aaaattattt gtgttggggg aaatgttgtg 1850

 ggggtggggt tgagttgggg gtattttcta attttttttg tacatttgga 1900

 acagtgacaa taaatgagac ccctttaaac tgtcaaaaaa aaaaaaaaaa 1950

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2000

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2050

 aaaaaaaaaa aaaaaaaaaa aaaa 2074

<210> 5658
<211> 505
<212> PRT
<213> Homo sapien

<400> 5658
 Met Arg Leu Arg Arg Leu Ala Leu Phe Pro Gly Val Ala Leu Leu
   1               5                  10                  15

 Leu Ala Ala Ala Arg Leu Ala Ala Ala Ser Asp Val Leu Glu Leu
                  20                  25                  30

 Thr Asp Asp Asn Phe Glu Ser Arg Ile Ser Asp Thr Gly Ser Ala
                  35                  40                  45

 Gly Leu Met Leu Val Glu Phe Phe Ala Pro Trp Cys Gly His Cys
                  50                  55                  60

 Lys Arg Leu Ala Pro Glu Tyr Glu Ala Ala Ala Thr Arg Leu Lys
                  65                  70                  75

 Gly Ile Val Pro Leu Ala Lys Val Asp Cys Thr Ala Asn Thr Asn
                  80                  85                  90

 Thr Cys Asn Lys Tyr Gly Val Ser Gly Tyr Pro Thr Leu Lys Ile
                  95                 100                 105

 Phe Arg Asp Gly Glu Glu Ala Gly Ala Tyr Asp Gly Pro Arg Thr
                 110                 115                 120

 Ala Asp Gly Ile Val Ser His Leu Lys Lys Gln Ala Gly Pro Ala
                 125                 130                 135

 Ser Val Pro Leu Arg Thr Glu Glu Glu Phe Lys Lys Phe Ile Ser
                 140                 145                 150

 Asp Lys Asp Ala Ser Ile Val Gly Phe Phe Asp Asp Ser Phe Ser
                 155                 160                 165

 Glu Ala His Ser Glu Phe Leu Lys Ala Ala Ser Asn Leu Arg Asp
                 170                 175                 180

 Asn Tyr Arg Phe Ala His Thr Asn Val Glu Ser Leu Val Asn Glu
                 185                 190                 195

 Tyr Asp Asp Asn Gly Glu Gly Ile Ile Leu Phe Arg Pro Ser His
                 200                 205                 210

 Leu Thr Asn Lys Phe Glu Asp Lys Thr Val Ala Tyr Thr Glu Gln
                 215                 220                 225

 Lys Met Thr Ser Gly Lys Ile Lys Lys Phe Ile Gln Glu Asn Ile
                 230                 235                 240

 Phe Gly Ile Cys Pro His Met Thr Glu Asp Asn Lys Asp Leu Ile
                 245                 250                 255

 Gln Gly Lys Asp Leu Leu Ile Ala Tyr Tyr Asp Val Asp Tyr Glu
                 260                 265                 270

 Lys Asn Ala Lys Gly Ser Asn Tyr Trp Arg Asn Arg Val Met Met
                 275                 280                 285

 Val Ala Lys Lys Phe Leu Asp Ala Gly His Lys Leu Asn Phe Ala
                 290                 295                 300

 Val Ala Ser Arg Lys Thr Phe Ser His Glu Leu Ser Asp Phe Gly
                 305                 310                 315

 Leu Glu Ser Thr Ala Gly Glu Ile Pro Val Val Ala Ile Arg Thr
                 320                 325                 330

 Ala Lys Gly Glu Lys Phe Val Met Gln Glu Glu Phe Ser Arg Asp
                 335                 340                 345

 Gly Lys Ala Leu Glu Arg Phe Leu Gln Asp Tyr Phe Asp Gly Asn
                 350                 355                 360

 Leu Lys Arg Tyr Leu Lys Ser Glu Pro Ile Pro Glu Ser Asn Asp
                 365                 370                 375

 Gly Pro Val Lys Val Val Val Ala Glu Asn Phe Asp Glu Ile Val
                 380                 385                 390

 Asn Asn Glu Asn Lys Asp Val Leu Ile Glu Phe Tyr Ala Pro Trp
                 395                 400                 405

 Cys Gly His Cys Lys Asn Leu Glu Pro Lys Tyr Lys Glu Leu Gly
                 410                 415                 420

 Glu Lys Leu Ser Lys Asp Pro Asn Ile Val Ile Ala Lys Met Asp
                 425                 430                 435

 Ala Thr Ala Asn Asp Val Pro Ser Pro Tyr Glu Val Arg Gly Phe
                 440                 445                 450

 Pro Thr Ile Tyr Phe Ser Pro Ala Asn Lys Lys Leu Asn Pro Lys
                 455                 460                 465

 Lys Tyr Glu Gly Gly Arg Glu Leu Ser Asp Phe Ile Ser Tyr Leu
                 470                 475                 480

 Gln Arg Glu Ala Thr Asn Pro Pro Val Ile Gln Glu Glu Lys Pro
                 485                 490                 495

 Lys Lys Lys Lys Lys Ala Gln Glu Asp Leu
                 500                 505

<210> 5659
<211> 947
<212> DNA
<213> Homo sapien

<400> 5659
 ggctcggggc cggggccagc acccacactg ggtctccaca gcggcatgga 50

 ggcctgcgtg tcttcactgc tggtgctggc cctgggggcc ctgtcagtag 100

 gcagctcctt tgggacccag atcatcgggg gccgggaggt gatcccccac 150

 tcgcgcccgt acatggcctc actgcagaga aatggctccc acctgtgcgg 200

 gggtgtcctg gtgcacccaa agtgggtgct gacggctgcc cactgcctgg 250

 cccagcggat ggcccagctg aggctggtgc tggggctcca caccctggac 300

 agccccggtc tcaccttcca catcaaggca gccatccagc accctcgcta 350

 caagcccgtc cctgccctgg agaacgacct cgcgctgctt cagctggacg 400

 ggaaagtgaa gcccagccgg accatccggc cgttggccct gcccagtaag 450

 cgccaggtgg tggcagcagg gactcggtgc agcatggccg gctgggggct 500

 gacccaccag ggcgggcgcc tgtcccgggt gctgcgggag ctggacctcc 550

 aagtgctgga cacccgcatg tgtaacaaca gccgcttctg gaacggcagc 600

 ctctccccca gcatggtctg cctggcggcc gactccaagg accaggctcc 650

 ctgcaagggt gactcgggcg ggcccctggt gtgtggcaaa ggccgggtgt 700

 tggccggagt cctgtccttc agctccaggg tctgcactga catcttcaag 750

 cctcccgtgg ccaccgctgt ggcgccttac gtgtcctgga tcaggaaggt 800

 caccggccga tcggcctgat gccctggggt gatggggacc ccctcgctgt 850

 ctccacagga cccttcccct ccaggggtgc agtggggtgg gtgaggacgg 900

 gtgggaggga cagggaggga ccaataaatc ataatgaaga aacgctc 947

<210> 5660
<211> 257
<212> PRT
<213> Homo sapien

<400> 5660
 Met Glu Ala Cys Val Ser Ser Leu Leu Val Leu Ala Leu Gly Ala
   1               5                  10                  15

 Leu Ser Val Gly Ser Ser Phe Gly Thr Gln Ile Ile Gly Gly Arg
                  20                  25                  30

 Glu Val Ile Pro His Ser Arg Pro Tyr Met Ala Ser Leu Gln Arg
                  35                  40                  45

 Asn Gly Ser His Leu Cys Gly Gly Val Leu Val His Pro Lys Trp
                  50                  55                  60

 Val Leu Thr Ala Ala His Cys Leu Ala Gln Arg Met Ala Gln Leu
                  65                  70                  75

 Arg Leu Val Leu Gly Leu His Thr Leu Asp Ser Pro Gly Leu Thr
                  80                  85                  90

 Phe His Ile Lys Ala Ala Ile Gln His Pro Arg Tyr Lys Pro Val
                  95                 100                 105

 Pro Ala Leu Glu Asn Asp Leu Ala Leu Leu Gln Leu Asp Gly Lys
                 110                 115                 120

 Val Lys Pro Ser Arg Thr Ile Arg Pro Leu Ala Leu Pro Ser Lys
                 125                 130                 135

 Arg Gln Val Val Ala Ala Gly Thr Arg Cys Ser Met Ala Gly Trp
                 140                 145                 150

 Gly Leu Thr His Gln Gly Gly Arg Leu Ser Arg Val Leu Arg Glu
                 155                 160                 165

 Leu Asp Leu Gln Val Leu Asp Thr Arg Met Cys Asn Asn Ser Arg
                 170                 175                 180

 Phe Trp Asn Gly Ser Leu Ser Pro Ser Met Val Cys Leu Ala Ala
                 185                 190                 195

 Asp Ser Lys Asp Gln Ala Pro Cys Lys Gly Asp Ser Gly Gly Pro
                 200                 205                 210

 Leu Val Cys Gly Lys Gly Arg Val Leu Ala Gly Val Leu Ser Phe
                 215                 220                 225

 Ser Ser Arg Val Cys Thr Asp Ile Phe Lys Pro Pro Val Ala Thr
                 230                 235                 240

 Ala Val Ala Pro Tyr Val Ser Trp Ile Arg Lys Val Thr Gly Arg
                 245                 250                 255

 Ser Ala


<210> 5661
<211> 1877
<212> DNA
<213> Homo sapien

<400> 5661
 cgcccccaga gtctggcttt ccgcggctgc ccgcctcgcg cgtcttccct 50

 gcccgggtct cctcgctgtc gccgccgctg ccacaccatg gccttcgtca 100

 ccaggcagtt catgcgttcc gtgtcctcct cgtccaccgc ctcggcctcg 150

 gccaagaaga taatcgtcaa gcacgtgacg gtcatcggcg gcgggctgat 200

 gggcgccggc attgcccagg ttgctgcagc aactggtcac acagtagtgt 250

 tggtagacca gacagaggac atcctggcaa aatccaaaaa gggaattgag 300

 gaaagcctta ggaaagtggc aaagaagaag tttgcagaaa accctaaggc 350

 cggcgatgaa tttgtggaga agaccctgag caccatagcg accagcacgg 400

 atgcagcctc cgttgtccac agcacagact tggtggtgga agccatcgtg 450

 gagaatctga aggtgaaaaa cgagctcttc aaaaggctgg acaagtttgc 500

 tgctgaacat acaatctttg ccagcaacac ttcctccttg catattacaa 550

 gcatagctaa tgccaccacc agacaagacc gattcgctgg cctccatttc 600

 ttcaacccag tgcctgtcat gaaacttgtg gaggtcatta aaacaccaat 650

 gaccagccag aagacatttg aatctttggt agactttagc aaagccctag 700

 gaaagcatcc tgtttcttgc aaggacactc ctgggtttat tgtgaaccgc 750

 ctcctggttc catacctcat ggaagcaatc aggctgtatg aacgaggtga 800

 cgcatccaaa gaagacattg acactgctat gaaattagga gccggttacc 850

 ccatgggccc atttgagctt ctagattatg tcggactgga tactacgaag 900

 ttcatcgtgg atgggtggca tgaaatggat gcagagaacc cattacatca 950

 gcccagccca tccttaaata agctggtagc agagaacaag ttcggcaaga 1000

 agactggaga aggattttac aaatacaagt gatgtgcagc ttctccggct 1050

 ctgagaagaa cacctgagag cgctttccag ccagtgcccc gagtgcctgt 1100

 gggaatgctc tttggtcaga cattccctca cacagtacag tttaataaat 1150

 gtgcattttg attgtaatct atcgaagtga ttattacacc agttacagca 1200

 gtaatagatt ctccattaag aaataattcc cttttttagt ctgttcattt 1250

 ctgtgtattt tctaaacagc tttacaccct tggtgccttg gagcaaacat 1300

 gttttttgaa ccttgtcatt tttgtgaaga attgcctaga ttccttctct 1350

 catcaacggg aaagtacttc ctctgagagt gcgagtgcac catgctcact 1400

 gttgctgcgt gggagagtca caagccactg gcaagcaagt ggtatagtct 1450

 gtgaagcact gcagcgagca gcacctggat cttgccttta taagaacatt 1500

 ttactacctg cagctttgag tcttgcccta cattttgggc atgacataag 1550

 atgtgtcttt attcagctcg tcgtgaagat gctgctgctg aatgggtcag 1600

 catatctctg tttgcatggt ttgcaggagg tcggttttca tggtcattca 1650

 gttccacaga tctgaatgat tactgtctgt ctgtgtcttt tttccatgag 1700

 aaatcactgt tgcaaattgc ctataaattg actctactaa aataacaatg 1750

 tttcagtctg aaaatttgaa ttgaaaaaaa tgtataatat aaaattgtaa 1800

 tacactcaaa tgattataaa agtaaaagtt ggtaatttag gcaaaaaaaa 1850

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 1877

<210> 5662
<211> 314
<212> PRT
<213> Homo sapien

<400> 5662
 Met Ala Phe Val Thr Arg Gln Phe Met Arg Ser Val Ser Ser Ser
   1               5                  10                  15

 Ser Thr Ala Ser Ala Ser Ala Lys Lys Ile Ile Val Lys His Val
                  20                  25                  30

 Thr Val Ile Gly Gly Gly Leu Met Gly Ala Gly Ile Ala Gln Val
                  35                  40                  45

 Ala Ala Ala Thr Gly His Thr Val Val Leu Val Asp Gln Thr Glu
                  50                  55                  60

 Asp Ile Leu Ala Lys Ser Lys Lys Gly Ile Glu Glu Ser Leu Arg
                  65                  70                  75

 Lys Val Ala Lys Lys Lys Phe Ala Glu Asn Pro Lys Ala Gly Asp
                  80                  85                  90

 Glu Phe Val Glu Lys Thr Leu Ser Thr Ile Ala Thr Ser Thr Asp
                  95                 100                 105

 Ala Ala Ser Val Val His Ser Thr Asp Leu Val Val Glu Ala Ile
                 110                 115                 120

 Val Glu Asn Leu Lys Val Lys Asn Glu Leu Phe Lys Arg Leu Asp
                 125                 130                 135

 Lys Phe Ala Ala Glu His Thr Ile Phe Ala Ser Asn Thr Ser Ser
                 140                 145                 150

 Leu His Ile Thr Ser Ile Ala Asn Ala Thr Thr Arg Gln Asp Arg
                 155                 160                 165

 Phe Ala Gly Leu His Phe Phe Asn Pro Val Pro Val Met Lys Leu
                 170                 175                 180

 Val Glu Val Ile Lys Thr Pro Met Thr Ser Gln Lys Thr Phe Glu
                 185                 190                 195

 Ser Leu Val Asp Phe Ser Lys Ala Leu Gly Lys His Pro Val Ser
                 200                 205                 210

 Cys Lys Asp Thr Pro Gly Phe Ile Val Asn Arg Leu Leu Val Pro
                 215                 220                 225

 Tyr Leu Met Glu Ala Ile Arg Leu Tyr Glu Arg Gly Asp Ala Ser
                 230                 235                 240

 Lys Glu Asp Ile Asp Thr Ala Met Lys Leu Gly Ala Gly Tyr Pro
                 245                 250                 255

 Met Gly Pro Phe Glu Leu Leu Asp Tyr Val Gly Leu Asp Thr Thr
                 260                 265                 270

 Lys Phe Ile Val Asp Gly Trp His Glu Met Asp Ala Glu Asn Pro
                 275                 280                 285

 Leu His Gln Pro Ser Pro Ser Leu Asn Lys Leu Val Ala Glu Asn
                 290                 295                 300

 Lys Phe Gly Lys Lys Thr Gly Glu Gly Phe Tyr Lys Tyr Lys
                 305                 310

<210> 5663
<211> 2145
<212> DNA
<213> Homo sapien

<400> 5663
 atcttttttc atcttctagc tgtagctcgg gctgcttgtc ggcttggctc 50

 cccctccccc ctttgctctc tgcctcgtct ttccccagga cttcgctatt 100

 ttgctttttt aaaaaaaggc aagaaagaac taaactcccc cctccctctc 150

 ctccagtcgg gctgcacctc tgccttgcac tttgcacaga ggtagagagc 200

 gcgcgaggga gagagaggaa agaaaaaaaa taataaagag agccaagcag 250

 aagaggaggc gagaagcatg aagtgttaac tcccccgtgc caaggcccgc 300

 gccgcccgga cagacgcccg ccgcgccttc cagccccgag cggacgccgc 350

 gcgccgccct gcctgcagcc cgggccggcg acggcgagcc cttccttatg 400

 caaagcgcgc cagcagcgcg aaggcgggac gccgcgcacc gggccgggct 450

 cctccagctt cgccgccgca gccaccaccg ccgccaccgc agctcgcgga 500

 ggatcttccc gagcctgaag ccgccggctc ggcgcgcaag gaggcgagcg 550

 caaggagggg ccggggcgag cgagggagca cattggcgtg agcagggggg 600

 agggagggcg ggcgcggggg gcgcgggcag ggcggggggg tgtgtgtgtg 650

 agcgcgcttg gaggtttcgg gccagccacc gccgcgcaag ctagaagcgc 700

 cccagcccgg caagctggct cacccgctgg ccacccagca cagcccgctg 750

 gcccctctcc tgcagcccat ctggcggagc ggcggcggcg gcggcggcgg 800

 caggagaatg gcatcagaac tggcaatgag caactccgac ctgcccacca 850

 gtcccctggc catggaatat gttaatgact tcgatctgat gaagtttgaa 900

 gtgaaaaagg aaccggtgga gaccgaccgc atcatcagcc agtgcggccg 950

 tctcatcgcc gggggctcgc tgtcctccac ccccatgagc acgccgtgca 1000

 gctcggtgcc cccttccccc agcttctcgg cgcccagccc gggctcgggc 1050

 agcgagcaga aggcgcacct ggaagactac tactggatga ccggctaccc 1100

 gcagcagctg aaccccgagg cgctgggctt cagccccgag gacgcggtcg 1150

 aggcgctcat cagcaacagc caccagctcc agggcggctt cgatggctac 1200

 gcgcgcgggg cgcagcagct ggccgcggcg gccggggccg gtgccggcgc 1250

 ctccttgggc ggcagcggcg aggagatggg ccccgcggcc gccgtggtgt 1300

 ccgccgtgat cgccgcggcc gccgcgcaga gcggcgcggg cccgcactac 1350

 caccaccacc accaccacgc cgccggccac caccaccacc cgacggccgg 1400

 cgcgcccggc gccgcgggca gcgcggccgc ctcggccggt ggcgctgggg 1450

 gcgcgggcgg cggtggcccg gccagcgctg ggggcggcgg cggcggcggc 1500

 ggcggcggag gcggcggggg cgcggcgggg gcggggggcg ccctgcaccc 1550

 gcaccacgcc gccggcggcc tgcacttcga cgaccgcttc tccgacgagc 1600

 agctggtgac catgtctgtg cgcgagctga accggcagct gcgcggggtc 1650

 agcaaggagg aggtgatccg gctgaagcag aagaggcgga ccctgaaaaa 1700

 ccgcggctat gcccagtcct gccgcttcaa gagggtgcag cagagacacg 1750

 tcctggagtc ggagaagaac cagctgctgc agcaagtcga ccacctcaag 1800

 caggagatct ccaggctggt gcgcgagagg gacgcgtaca aggagaaata 1850

 cgagaagttg gtgagcagcg gcttccgaga aaacggctcg agcagcgaca 1900

 acccgtcctc tcccgagttt ttcataactg agcccactcg caagttggag 1950

 ccatcagtgg gatacgccac attttggaag ccccagcatc gtgtacttac 2000

 cagtgtgttc acaaaatgaa atttgtgtga gagctgtaca ttaaaaaaaa 2050

 catcattatt attattattt gcagtcatgg agaaccacct acccctgact 2100

 tctgtttagt ctccttttta aataatactg tgttagaaaa aaaaa 2145

<210> 5664
<211> 403
<212> PRT
<213> Homo sapien

<400> 5664
 Met Ala Ser Glu Leu Ala Met Ser Asn Ser Asp Leu Pro Thr Ser
   1               5                  10                  15

 Pro Leu Ala Met Glu Tyr Val Asn Asp Phe Asp Leu Met Lys Phe
                  20                  25                  30

 Glu Val Lys Lys Glu Pro Val Glu Thr Asp Arg Ile Ile Ser Gln
                  35                  40                  45

 Cys Gly Arg Leu Ile Ala Gly Gly Ser Leu Ser Ser Thr Pro Met
                  50                  55                  60

 Ser Thr Pro Cys Ser Ser Val Pro Pro Ser Pro Ser Phe Ser Ala
                  65                  70                  75

 Pro Ser Pro Gly Ser Gly Ser Glu Gln Lys Ala His Leu Glu Asp
                  80                  85                  90

 Tyr Tyr Trp Met Thr Gly Tyr Pro Gln Gln Leu Asn Pro Glu Ala
                  95                 100                 105

 Leu Gly Phe Ser Pro Glu Asp Ala Val Glu Ala Leu Ile Ser Asn
                 110                 115                 120

 Ser His Gln Leu Gln Gly Gly Phe Asp Gly Tyr Ala Arg Gly Ala
                 125                 130                 135

 Gln Gln Leu Ala Ala Ala Ala Gly Ala Gly Ala Gly Ala Ser Leu
                 140                 145                 150

 Gly Gly Ser Gly Glu Glu Met Gly Pro Ala Ala Ala Val Val Ser
                 155                 160                 165

 Ala Val Ile Ala Ala Ala Ala Ala Gln Ser Gly Ala Gly Pro His
                 170                 175                 180

 Tyr His His His His His His Ala Ala Gly His His His His Pro
                 185                 190                 195

 Thr Ala Gly Ala Pro Gly Ala Ala Gly Ser Ala Ala Ala Ser Ala
                 200                 205                 210

 Gly Gly Ala Gly Gly Ala Gly Gly Gly Gly Pro Ala Ser Ala Gly
                 215                 220                 225

 Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Gly Ala Ala
                 230                 235                 240

 Gly Ala Gly Gly Ala Leu His Pro His His Ala Ala Gly Gly Leu
                 245                 250                 255

 His Phe Asp Asp Arg Phe Ser Asp Glu Gln Leu Val Thr Met Ser
                 260                 265                 270

 Val Arg Glu Leu Asn Arg Gln Leu Arg Gly Val Ser Lys Glu Glu
                 275                 280                 285

 Val Ile Arg Leu Lys Gln Lys Arg Arg Thr Leu Lys Asn Arg Gly
                 290                 295                 300

 Tyr Ala Gln Ser Cys Arg Phe Lys Arg Val Gln Gln Arg His Val
                 305                 310                 315

 Leu Glu Ser Glu Lys Asn Gln Leu Leu Gln Gln Val Asp His Leu
                 320                 325                 330

 Lys Gln Glu Ile Ser Arg Leu Val Arg Glu Arg Asp Ala Tyr Lys
                 335                 340                 345

 Glu Lys Tyr Glu Lys Leu Val Ser Ser Gly Phe Arg Glu Asn Gly
                 350                 355                 360

 Ser Ser Ser Asp Asn Pro Ser Ser Pro Glu Phe Phe Ile Thr Glu
                 365                 370                 375

 Pro Thr Arg Lys Leu Glu Pro Ser Val Gly Tyr Ala Thr Phe Trp
                 380                 385                 390

 Lys Pro Gln His Arg Val Leu Thr Ser Val Phe Thr Lys
                 395                 400

<210> 5665
<211> 3225
<212> DNA
<213> Homo sapien

<400> 5665
 ggcggcagcg ccctgccgac gccggggagg gacgcaggca ggcggcgggc 50

 agcgggaggc ggcaccccgg tgctccccgc ggctctcggc ggagccccgc 100

 cgcccgccgc gccatggccc gaagaccccg gcacagcata tatagcagtg 150

 acgaggatga tgaggacttt gagatgtgtg accatgacta tgatgggctg 200

 cttcccaagt ctggaaagcg tcacttgggg aaaacaaggt ggacccggga 250

 agaggatgaa aaactgaaga agctggtgga acagaatgga acagatgact 300

 ggaaagttat tgccaattat ctcccgaatc gaacagatgt gcagtgccag 350

 caccgatggc agaaagtact aaaccctgag ctcatcaagg gtccttggac 400

 caaagaagaa gatcagagag tgatagagct tgtacagaaa tacggtccga 450

 aacgttggtc tgttattgcc aagcacttaa aggggagaat tggaaaacaa 500

 tgtagggaga ggtggcataa ccacttgaat ccagaagtta agaaaacctc 550

 ctggacagaa gaggaagaca gaattattta ccaggcacac aagagactgg 600

 ggaacagatg ggcagaaatc gcaaagctac tgcctggacg aactgataat 650

 gctatcaaga accactggaa ttctacaatg cgtcggaagg tcgaacagga 700

 aggttatctg caggagtctt caaaagccag ccagccagca gtggccacaa 750

 gcttccagaa gaacagtcat ttgatgggtt ttgctcaggc tccgcctaca 800

 gctcaactcc ctgccactgg ccagcccact gttaacaacg actattccta 850

 ttaccacatt tctgaagcac aaaatgtctc cagtcatgtt ccataccctg 900

 tagcgttaca tgtaaatata gtcaatgtcc ctcagccagc tgccgcagcc 950

 attcagagac actataatga tgaagaccct gagaaggaaa agcgaataaa 1000

 ggaattagaa ttgctcctaa tgtcaaccga gaatgagcta aaaggacagc 1050

 aggtgctacc aacacagaac cacacatgca gctaccccgg gtggcacagc 1100

 accaccattg ccgaccacac cagacctcat ggagacagtg cacctgtttc 1150

 ctgtttggga gaacaccact ccactccatc tctgccagcg gatcctggct 1200

 ccctacctga agaaagcgcc tcgccagcaa ggtgcatgat cgtccaccag 1250

 ggcaccattc tggataatgt taagaacctc ttagaatttg cagaaacact 1300

 ccaatttata gattctttct taaacacttc cagtaaccat gaaaactcag 1350

 acttggaaat gccttcttta acttccaccc ccctcattgg tcacaaattg 1400

 actgttacaa caccatttca tagagaccag actgtgaaaa ctcaaaagga 1450

 aaatactgtt tttagaaccc cagctatcaa aaggtcaatc ttagaaagct 1500

 ctccaagaac tcctacacca ttcaaacatg cacttgcagc tcaagaaatt 1550

 aaatacggtc ccctgaagat gctacctcag acaccctctc atctagtaga 1600

 agatctgcag gatgtgatca aacaggaatc tgatgaatct ggatttgttg 1650

 ctgagtttca agaaaatgga ccacccttac tgaagaaaat caaacaagag 1700

 gtggaatctc caactgataa atcaggaaac ttcttctgct cacaccactg 1750

 ggaaggggac agtctgaata cccaactgtt cacgcagacc tcgcctgtgc 1800

 gagatgcacc gaatattctt acaagctccg ttttaatggc accagcatca 1850

 gaagatgaag acaatgttct caaagcattt acagtaccta aaaacaggtc 1900

 cctggcgagc cccttgcagc cttgtagcag tacctgggaa cctgcatcct 1950

 gtggaaagat ggaggagcag atgacatctt ccagtcaagc tcgtaaatac 2000

 gtgaatgcat tctcagcccg gacgctggtc atgtgagaca tttccagaaa 2050

 agcattatgg ttttcagaac agttcaagtt gacttgggat atatcattcc 2100

 tcaacatgaa acttttcatg aatgggagaa gaacctattt ttgttgtggt 2150

 acaacagttg agagcacgac caagtgcatt tagttgaatg aagtcttctt 2200

 ggatttcacc caactaaaag gatttttaaa aataaataac agtcttacct 2250

 aaattattag gtaatgaatt gtagccagtt gttaatatct taatgcagat 2300

 ttttttaaaa aaaaacataa aatgatttat ctggtatttt aaaggatcca 2350

 acagatcagt attttttcct gtgatgggtt ttttgaaatt tgacacatta 2400

 aaaggtactc cagtatttca cttttctcga tcactaaaca tatgcatata 2450

 tttttaaaaa tcagtaaaag cattactcta agtgtagact taataccatg 2500

 tgacatttaa tccagattgt aaatgctcat ttatggttaa tgacattgaa 2550

 ggtacattta ttgtaccaaa ccattttatg agttttctgt tagcttgctt 2600

 taaaaattat tactgtaaga aatagtttta taaaaaatta tatttttatt 2650

 cagtaattta attttgtaaa tgccaaatga aaaacgtttt ttgctgctat 2700

 ggtcttagcc tgtagacatg ctgctagtat cagaggggca gtagagcttg 2750

 gacagaaaga aaagaaactt ggtgttaggt aattgactat gcactagtat 2800

 ttcagacttt ttaattttat atatatatac attttttttc cttctgcaat 2850

 acatttgaaa acttgtttgg gagactctgc attttttatt gtggtttttt 2900

 tgttattgtt ggtttataca agcatgcgtt gcacttcttt tttgggagat 2950

 gtgtgttgtt catgttctat gttttgtttt gtgtgtagcc tgactgtttt 3000

 ataatttggg agttctcgat ttgatccgca tcccctgtgg tttctaagtg 3050

 tatggtctca gaactgttgc atggatcctg tgtttgcaac tggggagaca 3100

 gaaactgtgg ttgatagcca gtcactgcct taagaacatt tgatgcaaga 3150

 tggccagcac tgaacttttg agatatgacg gtgtacttac tgccttgtag 3200

 caaaataaag atgtgccctt atttt 3225

<210> 5666
<211> 640
<212> PRT
<213> Homo sapien

<400> 5666
 Met Ala Arg Arg Pro Arg His Ser Ile Tyr Ser Ser Asp Glu Asp
   1               5                  10                  15

 Asp Glu Asp Phe Glu Met Cys Asp His Asp Tyr Asp Gly Leu Leu
                  20                  25                  30

 Pro Lys Ser Gly Lys Arg His Leu Gly Lys Thr Arg Trp Thr Arg
                  35                  40                  45

 Glu Glu Asp Glu Lys Leu Lys Lys Leu Val Glu Gln Asn Gly Thr
                  50                  55                  60

 Asp Asp Trp Lys Val Ile Ala Asn Tyr Leu Pro Asn Arg Thr Asp
                  65                  70                  75

 Val Gln Cys Gln His Arg Trp Gln Lys Val Leu Asn Pro Glu Leu
                  80                  85                  90

 Ile Lys Gly Pro Trp Thr Lys Glu Glu Asp Gln Arg Val Ile Glu
                  95                 100                 105

 Leu Val Gln Lys Tyr Gly Pro Lys Arg Trp Ser Val Ile Ala Lys
                 110                 115                 120

 His Leu Lys Gly Arg Ile Gly Lys Gln Cys Arg Glu Arg Trp His
                 125                 130                 135

 Asn His Leu Asn Pro Glu Val Lys Lys Thr Ser Trp Thr Glu Glu
                 140                 145                 150

 Glu Asp Arg Ile Ile Tyr Gln Ala His Lys Arg Leu Gly Asn Arg
                 155                 160                 165

 Trp Ala Glu Ile Ala Lys Leu Leu Pro Gly Arg Thr Asp Asn Ala
                 170                 175                 180

 Ile Lys Asn His Trp Asn Ser Thr Met Arg Arg Lys Val Glu Gln
                 185                 190                 195

 Glu Gly Tyr Leu Gln Glu Ser Ser Lys Ala Ser Gln Pro Ala Val
                 200                 205                 210

 Ala Thr Ser Phe Gln Lys Asn Ser His Leu Met Gly Phe Ala Gln
                 215                 220                 225

 Ala Pro Pro Thr Ala Gln Leu Pro Ala Thr Gly Gln Pro Thr Val
                 230                 235                 240

 Asn Asn Asp Tyr Ser Tyr Tyr His Ile Ser Glu Ala Gln Asn Val
                 245                 250                 255

 Ser Ser His Val Pro Tyr Pro Val Ala Leu His Val Asn Ile Val
                 260                 265                 270

 Asn Val Pro Gln Pro Ala Ala Ala Ala Ile Gln Arg His Tyr Asn
                 275                 280                 285

 Asp Glu Asp Pro Glu Lys Glu Lys Arg Ile Lys Glu Leu Glu Leu
                 290                 295                 300

 Leu Leu Met Ser Thr Glu Asn Glu Leu Lys Gly Gln Gln Val Leu
                 305                 310                 315

 Pro Thr Gln Asn His Thr Cys Ser Tyr Pro Gly Trp His Ser Thr
                 320                 325                 330

 Thr Ile Ala Asp His Thr Arg Pro His Gly Asp Ser Ala Pro Val
                 335                 340                 345

 Ser Cys Leu Gly Glu His His Ser Thr Pro Ser Leu Pro Ala Asp
                 350                 355                 360

 Pro Gly Ser Leu Pro Glu Glu Ser Ala Ser Pro Ala Arg Cys Met
                 365                 370                 375

 Ile Val His Gln Gly Thr Ile Leu Asp Asn Val Lys Asn Leu Leu
                 380                 385                 390

 Glu Phe Ala Glu Thr Leu Gln Phe Ile Asp Ser Phe Leu Asn Thr
                 395                 400                 405

 Ser Ser Asn His Glu Asn Ser Asp Leu Glu Met Pro Ser Leu Thr
                 410                 415                 420

 Ser Thr Pro Leu Ile Gly His Lys Leu Thr Val Thr Thr Pro Phe
                 425                 430                 435

 His Arg Asp Gln Thr Val Lys Thr Gln Lys Glu Asn Thr Val Phe
                 440                 445                 450

 Arg Thr Pro Ala Ile Lys Arg Ser Ile Leu Glu Ser Ser Pro Arg
                 455                 460                 465

 Thr Pro Thr Pro Phe Lys His Ala Leu Ala Ala Gln Glu Ile Lys
                 470                 475                 480

 Tyr Gly Pro Leu Lys Met Leu Pro Gln Thr Pro Ser His Leu Val
                 485                 490                 495

 Glu Asp Leu Gln Asp Val Ile Lys Gln Glu Ser Asp Glu Ser Gly
                 500                 505                 510

 Phe Val Ala Glu Phe Gln Glu Asn Gly Pro Pro Leu Leu Lys Lys
                 515                 520                 525

 Ile Lys Gln Glu Val Glu Ser Pro Thr Asp Lys Ser Gly Asn Phe
                 530                 535                 540

 Phe Cys Ser His His Trp Glu Gly Asp Ser Leu Asn Thr Gln Leu
                 545                 550                 555

 Phe Thr Gln Thr Ser Pro Val Arg Asp Ala Pro Asn Ile Leu Thr
                 560                 565                 570

 Ser Ser Val Leu Met Ala Pro Ala Ser Glu Asp Glu Asp Asn Val
                 575                 580                 585

 Leu Lys Ala Phe Thr Val Pro Lys Asn Arg Ser Leu Ala Ser Pro
                 590                 595                 600

 Leu Gln Pro Cys Ser Ser Thr Trp Glu Pro Ala Ser Cys Gly Lys
                 605                 610                 615

 Met Glu Glu Gln Met Thr Ser Ser Ser Gln Ala Arg Lys Tyr Val
                 620                 625                 630

 Asn Ala Phe Ser Ala Arg Thr Leu Val Met
                 635                 640

<210> 5667
<211> 1929
<212> DNA
<213> Homo sapien

<400> 5667
 acccccgcac ccagctccgc agaccggcgg gcgcgcgcgg gctctggagg 50

 ccacgggcat gatgcttcgg gtcctggtgg gggctgtcct ccctgccatg 100

 ctactggctg ccccaccacc catcaacaag ctggcactgt tcccagataa 150

 gagtgcctgg tgcgaagcca agaacatcac ccagatcgtg ggccacagcg 200

 gctgtgaggc caagtccatc cagaacaggg cgtgcctagg acagtgcttc 250

 agctacagcg tccccaacac cttcccacag tccacagagt ccctggttca 300

 ctgtgactcc tgcatgccag cccagtccat gtgggagatt gtgacgctgg 350

 agtgcccggg ccacgaggag gtgcccaggg tggacaagct ggtggagaag 400

 atcctgcact gtagctgcca ggcctgcggc aaggagccta gtcacgaggg 450

 gctgagcgtc tatgtgcagg gcgaggacgg gccgggatcc cagcccggca 500

 cccaccctca cccccatccc cacccccatc ctggcgggca gacccctgag 550

 cccgaggacc cccctggggc cccccacaca gaggaagagg gggctgagga 600

 ctgaggcccc cccaactctt cctcccctct catccccctg tggaatgttg 650

 ggtctcactc tctggggaag tcaggggaga agctgaagcc cccctttggc 700

 actggatgga cttggcttca gactcggact tgaatgctgc ccggttgcca 750

 tggagatctg aaggggcggg gttagagcca agctgcacaa tttaatatat 800

 tcaagagtgg ggggaggaag cagaggtctt cagggctctt tttttggggg 850

 gggggtggtc tcttcctgtc tggcttctag agatgtgcct gtgggagggg 900

 gaggaagttg gctgagccat tgagtgctgg gggaggccat ccaagatggc 950

 atgaatcggg ctaaggtccc tgggggtgca gatggtactg ctgaggtccc 1000

 gggcttagtg tgagcatctt gccagcctca ggcttgaggg agggctgggc 1050

 tagaaagacc actggcagaa acaggaggct ccggccccac aggtttcccc 1100

 aaggcctctc accccacttc ccatctccag ggaagcgtcg ccccagtggc 1150

 actgaagtgg ccctccctca gcggaggggt ttgggagtca ggcctgggca 1200

 ggaccctgct gactcgtggc gcgggagctg ggagccaggc tctccgggcc 1250

 tttctctggc ttccttggct tgcctggtgg gggaagggga ggaggggaag 1300

 aaggaaaggg aagagtcttc caaggccaga gggaggggga caacccccca 1350

 agaccatccc tgaagacgag catccccctc ctctccctgt tagaaatgtt 1400

 agtgccccgc actgtgcccc aagttctagg ccccccagaa agctgtcaga 1450

 gccggccgcc ttctcccctc tcccagggat gctctttgta aatatcggat 1500

 gggtgtggga gtgaggggtt acctccctcg ccccaaggtt ccagaggccc 1550

 taggcgggat gggctcgctg aacctcgagg aactccagga cgaggaggac 1600

 atgggacttg cgtggacagt cagggttcac ttgggctctc tctagctccc 1650

 caattctgcc tgcctcctcc ctcccagctg cactttaacc ctagaaggtg 1700

 gggacctggg gggagggaca gggcaggcgg gcccatgaag aaagcccctc 1750

 gttgcccagc actgtctgcg tctgctcttc tgtgcccagg gtggctgcca 1800

 gcccactgcc tcctgcctgg ggtggcctgg ccctcctggc tgttgcgacg 1850

 cgggcttctg gagcttgtca ccattggaca gtctccctga tggaccctca 1900

 gtcttctcat gaataaattc ttcggaatt 1929

<210> 5668
<211> 180
<212> PRT
<213> Homo sapien

<400> 5668
 Met Leu Arg Val Leu Val Gly Ala Val Leu Pro Ala Met Leu Leu
   1               5                  10                  15

 Ala Ala Pro Pro Pro Ile Asn Lys Leu Ala Leu Phe Pro Asp Lys
                  20                  25                  30

 Ser Ala Trp Cys Glu Ala Lys Asn Ile Thr Gln Ile Val Gly His
                  35                  40                  45

 Ser Gly Cys Glu Ala Lys Ser Ile Gln Asn Arg Ala Cys Leu Gly
                  50                  55                  60

 Gln Cys Phe Ser Tyr Ser Val Pro Asn Thr Phe Pro Gln Ser Thr
                  65                  70                  75

 Glu Ser Leu Val His Cys Asp Ser Cys Met Pro Ala Gln Ser Met
                  80                  85                  90

 Trp Glu Ile Val Thr Leu Glu Cys Pro Gly His Glu Glu Val Pro
                  95                 100                 105

 Arg Val Asp Lys Leu Val Glu Lys Ile Leu His Cys Ser Cys Gln
                 110                 115                 120

 Ala Cys Gly Lys Glu Pro Ser His Glu Gly Leu Ser Val Tyr Val
                 125                 130                 135

 Gln Gly Glu Asp Gly Pro Gly Ser Gln Pro Gly Thr His Pro His
                 140                 145                 150

 Pro His Pro His Pro His Pro Gly Gly Gln Thr Pro Glu Pro Glu
                 155                 160                 165

 Asp Pro Pro Gly Ala Pro His Thr Glu Glu Glu Gly Ala Glu Asp
                 170                 175                 180

<210> 5669
<211> 2518
<212> DNA
<213> Homo sapien

<400> 5669
 cttcgggtgt acgtgctccg ggatcttcag cacccgcggc cgccatcgcc 50

 gtcgcttggc ttcttctgga ctcatctgcg ccacttgtcc gcttcacact 100

 ccgccgccat catggtgaag ctcgcgaagg caggtaaaaa tcaaggtgac 150

 cccaagaaaa tggctcctcc tccaaaggag gtagaagaag atagtgaaga 200

 tgaggaaatg tcagaagatg aagaagatga tagcagtgga gaagaggtcg 250

 tcatacctca gaagaaaggc aagaaggctg ctgcaacctc agcaaagaag 300

 gtggtcgttt ccccaacaaa aaaggttgca gttgccacac cagccaagaa 350

 agcagctgtc actccaggca aaaaggcagc agcaacacct gccaagaaga 400

 cagttacacc agccaaagca gttaccacac ctggcaagaa gggagccaca 450

 ccaggcaaag cattggtagc aactcctggt aagaagggtg ctgccatccc 500

 agccaagggg gcaaagaatg gcaagaatgc caagaaggaa gacagtgatg 550

 aagaggagga tgatgacagt gaggaggatg aggaggatga cgaggacgag 600

 gatgaggatg aagatgaaat tgaaccagca gcgatgaaag cagcagctgc 650

 tgcccctgcc tcagaggatg aggacgatga ggatgacgaa gatgatgagg 700

 atgacgatga cgatgaggaa gatgactctg aagaagaagc tatggagact 750

 acaccagcca aaggaaagaa agctgcaaaa gttgttcctg tgaaagccaa 800

 gaacgtggct gaggatgaag atgaagaaga ggatgatgag gacgaggatg 850

 acgacgacga cgaagatgat gaagatgatg atgatgaaga tgatgaggag 900

 gaggaagaag aggaggagga agagcctgtc aaagaagcac ctggaaaacg 950

 aaagaaggaa atggccaaac agaaagcagc tcctgaagcc aagaaacaga 1000

 aagtggaagg cacagaaccg actacggctt tcaatctctt tgttggaaac 1050

 ctaaacttta acaaatctgc tcctgaatta aaaactggta tcagcgatgt 1100

 ttttgctaaa aatgatcttg ctgttgtgga tgtcagaatt ggtatgacta 1150

 ggaaatttgg ttatgtggat tttgaatctg ctgaagacct ggagaaagcg 1200

 ttggaactca ctggtttgaa agtctttggc aatgaaatta aactagagaa 1250

 accaaaagga aaagacagta agaaagagcg agatgcgaga acacttttgg 1300

 ctaaaaatct cccttacaaa gtcactcagg atgaattgaa agaagtgttt 1350

 gaagatgctg cggagatcag attagtcagc aaggatggga aaagtaaagg 1400

 gattgcttat attgaattta agacagaagc tgatgcagag aaaacctttg 1450

 aagaaaagca gggaacagag atcgatgggc gatctatttc cctgtactat 1500

 actggagaga aaggtcaaaa tcaagactat agaggtggaa agaatagcac 1550

 ttggagtggt gaatcaaaaa ctctggtttt aagcaacctc tcctacagtg 1600

 caacagaaga aactcttcag gaagtatttg agaaagcaac ttttatcaaa 1650

 gtaccccaga accaaaatgg caaatctaaa gggtatgcat ttatagagtt 1700

 tgcttcattc gaagacgcta aagaagcttt aaattcctgt aataaaaggg 1750

 aaattgaggg cagagcaatc aggctggagt tgcaaggacc caggggatca 1800

 cctaatgcca gaagccagcc atccaaaact ctgtttgtca aaggcctgtc 1850

 tgaggatacc actgaagaga cattaaagga gtcatttgac ggctccgttc 1900

 gggcaaggat agttactgac cgggaaactg ggtcctccaa agggtttggt 1950

 tttgtagact tcaacagtga ggaggatgcc aaggaggcca tggaagacgg 2000

 tgaaattgat ggaaataaag ttaccttgga ctgggccaaa cctaagggtg 2050

 aaggtggctt cgggggtcgt ggtggaggca gaggcggctt tggaggacga 2100

 ggtggtggta gaggaggccg aggaggattt ggtggcagag gccggggagg 2150

 ctttggaggg cgaggaggct tccgaggagg cagaggagga ggaggtgacc 2200

 acaagccaca aggaaagaag acgaagtttg aatagcttct gtccctctgc 2250

 tttccctttt ccatttgaaa gaaaggactc tggggttttt actgttacct 2300

 gatcaatgac agagccttct gaggacattc caagacagta tacagtcctg 2350

 tggtctcctt ggaaatccgt ctagttaaca tttcaagggc aataccgtgt 2400

 tggttttgac tggatattca tataaacttt ttaaagagtt gagtgataga 2450

 gctaaccctt atctgtaagt tttgaattta tattgtttca tcccatgtac 2500

 aaaaccattt tttcctac 2518

<210> 5670
<211> 707
<212> PRT
<213> Homo sapien

<400> 5670
 Met Val Lys Leu Ala Lys Ala Gly Lys Asn Gln Gly Asp Pro Lys
   1               5                  10                  15

 Lys Met Ala Pro Pro Pro Lys Glu Val Glu Glu Asp Ser Glu Asp
                  20                  25                  30

 Glu Glu Met Ser Glu Asp Glu Glu Asp Asp Ser Ser Gly Glu Glu
                  35                  40                  45

 Val Val Ile Pro Gln Lys Lys Gly Lys Lys Ala Ala Ala Thr Ser
                  50                  55                  60

 Ala Lys Lys Val Val Val Ser Pro Thr Lys Lys Val Ala Val Ala
                  65                  70                  75

 Thr Pro Ala Lys Lys Ala Ala Val Thr Pro Gly Lys Lys Ala Ala
                  80                  85                  90

 Ala Thr Pro Ala Lys Lys Thr Val Thr Pro Ala Lys Ala Val Thr
                  95                 100                 105

 Thr Pro Gly Lys Lys Gly Ala Thr Pro Gly Lys Ala Leu Val Ala
                 110                 115                 120

 Thr Pro Gly Lys Lys Gly Ala Ala Ile Pro Ala Lys Gly Ala Lys
                 125                 130                 135

 Asn Gly Lys Asn Ala Lys Lys Glu Asp Ser Asp Glu Glu Glu Asp
                 140                 145                 150

 Asp Asp Ser Glu Glu Asp Glu Glu Asp Asp Glu Asp Glu Asp Glu
                 155                 160                 165

 Asp Glu Asp Glu Ile Glu Pro Ala Ala Met Lys Ala Ala Ala Ala
                 170                 175                 180

 Ala Pro Ala Ser Glu Asp Glu Asp Asp Glu Asp Asp Glu Asp Asp
                 185                 190                 195

 Glu Asp Asp Asp Asp Asp Glu Glu Asp Asp Ser Glu Glu Glu Ala
                 200                 205                 210

 Met Glu Thr Thr Pro Ala Lys Gly Lys Lys Ala Ala Lys Val Val
                 215                 220                 225

 Pro Val Lys Ala Lys Asn Val Ala Glu Asp Glu Asp Glu Glu Glu
                 230                 235                 240

 Asp Asp Glu Asp Glu Asp Asp Asp Asp Asp Glu Asp Asp Glu Asp
                 245                 250                 255

 Asp Asp Asp Glu Asp Asp Glu Glu Glu Glu Glu Glu Glu Glu Glu
                 260                 265                 270

 Glu Pro Val Lys Glu Ala Pro Gly Lys Arg Lys Lys Glu Met Ala
                 275                 280                 285

 Lys Gln Lys Ala Ala Pro Glu Ala Lys Lys Gln Lys Val Glu Gly
                 290                 295                 300

 Thr Glu Pro Thr Thr Ala Phe Asn Leu Phe Val Gly Asn Leu Asn
                 305                 310                 315

 Phe Asn Lys Ser Ala Pro Glu Leu Lys Thr Gly Ile Ser Asp Val
                 320                 325                 330

 Phe Ala Lys Asn Asp Leu Ala Val Val Asp Val Arg Ile Gly Met
                 335                 340                 345

 Thr Arg Lys Phe Gly Tyr Val Asp Phe Glu Ser Ala Glu Asp Leu
                 350                 355                 360

 Glu Lys Ala Leu Glu Leu Thr Gly Leu Lys Val Phe Gly Asn Glu
                 365                 370                 375

 Ile Lys Leu Glu Lys Pro Lys Gly Lys Asp Ser Lys Lys Glu Arg
                 380                 385                 390

 Asp Ala Arg Thr Leu Leu Ala Lys Asn Leu Pro Tyr Lys Val Thr
                 395                 400                 405

 Gln Asp Glu Leu Lys Glu Val Phe Glu Asp Ala Ala Glu Ile Arg
                 410                 415                 420

 Leu Val Ser Lys Asp Gly Lys Ser Lys Gly Ile Ala Tyr Ile Glu
                 425                 430                 435

 Phe Lys Thr Glu Ala Asp Ala Glu Lys Thr Phe Glu Glu Lys Gln
                 440                 445                 450

 Gly Thr Glu Ile Asp Gly Arg Ser Ile Ser Leu Tyr Tyr Thr Gly
                 455                 460                 465

 Glu Lys Gly Gln Asn Gln Asp Tyr Arg Gly Gly Lys Asn Ser Thr
                 470                 475                 480

 Trp Ser Gly Glu Ser Lys Thr Leu Val Leu Ser Asn Leu Ser Tyr
                 485                 490                 495

 Ser Ala Thr Glu Glu Thr Leu Gln Glu Val Phe Glu Lys Ala Thr
                 500                 505                 510

 Phe Ile Lys Val Pro Gln Asn Gln Asn Gly Lys Ser Lys Gly Tyr
                 515                 520                 525

 Ala Phe Ile Glu Phe Ala Ser Phe Glu Asp Ala Lys Glu Ala Leu
                 530                 535                 540

 Asn Ser Cys Asn Lys Arg Glu Ile Glu Gly Arg Ala Ile Arg Leu
                 545                 550                 555

 Glu Leu Gln Gly Pro Arg Gly Ser Pro Asn Ala Arg Ser Gln Pro
                 560                 565                 570

 Ser Lys Thr Leu Phe Val Lys Gly Leu Ser Glu Asp Thr Thr Glu
                 575                 580                 585

 Glu Thr Leu Lys Glu Ser Phe Asp Gly Ser Val Arg Ala Arg Ile
                 590                 595                 600

 Val Thr Asp Arg Glu Thr Gly Ser Ser Lys Gly Phe Gly Phe Val
                 605                 610                 615

 Asp Phe Asn Ser Glu Glu Asp Ala Lys Glu Ala Met Glu Asp Gly
                 620                 625                 630

 Glu Ile Asp Gly Asn Lys Val Thr Leu Asp Trp Ala Lys Pro Lys
                 635                 640                 645

 Gly Glu Gly Gly Phe Gly Gly Arg Gly Gly Gly Arg Gly Gly Phe
                 650                 655                 660

 Gly Gly Arg Gly Gly Gly Arg Gly Gly Arg Gly Gly Phe Gly Gly
                 665                 670                 675

 Arg Gly Arg Gly Gly Phe Gly Gly Arg Gly Gly Phe Arg Gly Gly
                 680                 685                 690

 Arg Gly Gly Gly Gly Asp His Lys Pro Gln Gly Lys Lys Thr Lys
                 695                 700                 705

 Phe Glu


<210> 5671
<211> 630
<212> DNA
<213> Homo sapien

<400> 5671
 atggtcgact acctagcaaa taagcccaag ggtcagaatt ctttggcttt 50

 acacaaagtc atcatggtgg gcagtggtgg cgtgggcaag tcagctctga 100

 ctctacagtt catgtacgat gagtttgtgg aggactatga gcctaccaaa 150

 gcagacagct atcggaagaa ggtagtgcta gatggggagg aagtccagat 200

 cgatatctta gatacagctg ggcaggagga ctacgctgca attagagaca 250

 actacttccg aagtggggag gggttcctct gtgttttctc tattacagaa 300

 atggaatcct ttgcagctac agctgacttc agggagcaga ttttaagagt 350

 aaaagaagat gagaatgttc catttctact ggttggtaac aaatcagatt 400

 tagaagataa aagacaggtt tctgtagaag aggcaaaaaa cagagctgag 450

 cagtggaatg ttaactacgt ggaaacatct gctaaaacac gagctaatgt 500

 tgacaaggta ttttttgatt taatgagaga aattcgagcg agaaagatgg 550

 aagacagcaa agaaaagaat ggaaaaaaga agaggaaaag tttagccaag 600

 agaatcagag aaagatgctg cattttataa 630

<210> 5672
<211> 209
<212> PRT
<213> Homo sapien

<400> 5672
 Met Val Asp Tyr Leu Ala Asn Lys Pro Lys Gly Gln Asn Ser Leu
   1               5                  10                  15

 Ala Leu His Lys Val Ile Met Val Gly Ser Gly Gly Val Gly Lys
                  20                  25                  30

 Ser Ala Leu Thr Leu Gln Phe Met Tyr Asp Glu Phe Val Glu Asp
                  35                  40                  45

 Tyr Glu Pro Thr Lys Ala Asp Ser Tyr Arg Lys Lys Val Val Leu
                  50                  55                  60

 Asp Gly Glu Glu Val Gln Ile Asp Ile Leu Asp Thr Ala Gly Gln
                  65                  70                  75

 Glu Asp Tyr Ala Ala Ile Arg Asp Asn Tyr Phe Arg Ser Gly Glu
                  80                  85                  90

 Gly Phe Leu Cys Val Phe Ser Ile Thr Glu Met Glu Ser Phe Ala
                  95                 100                 105

 Ala Thr Ala Asp Phe Arg Glu Gln Ile Leu Arg Val Lys Glu Asp
                 110                 115                 120

 Glu Asn Val Pro Phe Leu Leu Val Gly Asn Lys Ser Asp Leu Glu
                 125                 130                 135

 Asp Lys Arg Gln Val Ser Val Glu Glu Ala Lys Asn Arg Ala Glu
                 140                 145                 150

 Gln Trp Asn Val Asn Tyr Val Glu Thr Ser Ala Lys Thr Arg Ala
                 155                 160                 165

 Asn Val Asp Lys Val Phe Phe Asp Leu Met Arg Glu Ile Arg Ala
                 170                 175                 180

 Arg Lys Met Glu Asp Ser Lys Glu Lys Asn Gly Lys Lys Lys Arg
                 185                 190                 195

 Lys Ser Leu Ala Lys Arg Ile Arg Glu Arg Cys Cys Ile Leu
                 200                 205

<210> 5673
<211> 4343
<212> DNA
<213> Homo sapien

<400> 5673
 agatttgata atgggctgca ttaaaagtaa agaaaacaaa agtccagcca 50

 ttaaatacag acctgaaaat actccagagc ctgtcagtac aagtgtgagc 100

 cattatggag cagaacccac tacagtgtca ccatgtccgt catcttcagc 150

 aaagggaaca gcagttaatt tcagcagtct ttccatgaca ccatttggag 200

 gatcctcagg ggtaacgcct tttggaggtg catcttcctc attttcagtg 250

 gtgccaagtt catatcctgc tggtttaaca ggtggtgtta ctatatttgt 300

 ggccttatat gattatgaag ctagaactac agaagacctt tcatttaaga 350

 agggtgaaag atttcaaata attaacaata cggaaggaga ttggtgggaa 400

 gcaagatcaa tcgctacagg aaagaatggt tatatcccga gcaattatgt 450

 agcgcctgca gattccattc aggcagaaga atggtatttt ggcaaaatgg 500

 ggagaaaaga tgctgaaaga ttacttttga atcctggaaa tcaacgaggt 550

 attttcttag taagagagag tgaaacaact aaaggtgctt attccctttc 600

 tattcgtgat tgggatgaga taaggggtga caatgtgaaa cactacaaaa 650

 ttaggaaact tgacaatggt ggatactata tcacaaccag agcacaattt 700

 gatactctgc agaaattggt gaaacactac acagaacatg ctgatggttt 750

 atgccacaag ttgacaactg tgtgtccaac tgtgaaacct cagactcaag 800

 gtctagcaaa agatgcttgg gaaatccctc gagaatcttt gcgactagag 850

 gttaaactag gacaaggatg tttcggcgaa gtgtggatgg gaacatggaa 900

 tggaaccacg aaagtagcaa tcaaaacact aaaaccaggt acaatgatgc 950

 cagaagcttt ccttcaagaa gctcagataa tgaaaaaatt aagacatgat 1000

 aaacttgttc cactatatgc tgttgtttct gaagaaccaa tttacattgt 1050

 cactgaattt atgtcaaaag gaagcttatt agatttcctt aaggaaggag 1100

 atggaaagta tttgaagctt ccacagctgg ttgatatggc tgctcagatt 1150

 gctgatggta tggcatatat tgaaagaatg aactatattc accgagatct 1200

 tcgggctgct aatattcttg taggagaaaa tcttgtgtgc aaaatagcag 1250

 actttggttt agcaaggtta attgaagaca atgaatacac agcaagacaa 1300

 ggtgcaaaat ttccaatcaa atggacagct cctgaagctg cactgtatgg 1350

 tcggtttaca ataaagtctg atgtctggtc atttggaatt ctgcaaacag 1400

 aactagtaac aaagggccga gtgccatatc caggtatggt gaaccgtgaa 1450

 gtactagaac aagtggagcg aggatacagg atgccgtgcc ctcagggctg 1500

 tccagaatcc ctccatgaat tgatgaatct gtgttggaag aaggaccctg 1550

 atgaaagacc aacatttgaa tatattcagt ccttcttgga agactacttc 1600

 actgctacag agccacagta ccagccagga gaaaatttat aattcaagta 1650

 gcctatttta tatgcacaaa tctgccaaaa tataaagaac ttgtgtagat 1700

 tttctacagg aatcaaaaga agaaaatctt ctttactctg catgttttta 1750

 atggtaaact ggaatcccag atatggttgc acaaaaccac ttttttttcc 1800

 ccaagtatta aactctaatg taccaatgat gaatttatca gcgtatttca 1850

 gggtccaaac aaaatagagc taagatactg atgacagtgt gggtgacagc 1900

 atggtaatga aggacagtga ggctcctgct tatttataaa tcatttcctt 1950

 tctttttttc cccaaagtca gaattgctca aagaaaatta tttattgtta 2000

 cagataaaac ttgagagata aaaagctata ccataataaa atctaaaatt 2050

 aaggaatatc atgggaccaa ataattccat tccagttttt taaagtttct 2100

 tgcatttatt attctcaaaa gttttttcta agttaaacag tcagtatgca 2150

 atcttaatat atgctttctt ttgcatggac atgggccagg tttttcaaaa 2200

 ggaatataaa caggatctca aacttgatta aatgttagac cacagaagtg 2250

 gaatttgaaa gtataatgca gtacattaat attcatgttc atggaactga 2300

 aagaataaga actttttcac ttcagtcctt ttctgaagag tttgacttag 2350

 aataatgaag gtaactagaa agtgagttaa tcttgtatga ggttgcattg 2400

 attttttaag gcaatatata attgaaacta ctgtccaatc aaaggggaaa 2450

 tgttttgatc tttagatagc atgcaaagta agacccagca ttttaaaagc 2500

 cctttttaaa aactagactt cgtactgtga gtattgctta tatgtcctta 2550

 tggggatggg tgccacaaat agaaaatatg accagatcag ggacttgaat 2600

 gcacttttgc tcatggtgaa tatagatgaa cagagaggaa aatgtattta 2650

 aaagaaatac gagaaaagaa aatgtgaaag ttttacaagt tagagggatg 2700

 gaaggtaatg tttaatgttg atgtcatgga gtgacagaat ggctttgctg 2750

 gcactcagag ctcctcactt agctatattc tgagactttg aagagttata 2800

 aagtataact ataaaactaa tttttcttac acactaaatg ggtatttgtt 2850

 caaaataatg aagttatggc ttcacattca ttgcagtggg atatggtttt 2900

 tatgtaaaac atttttagaa ctccagtttt caaatcatgt ttgaatctac 2950

 attcactttt ttttgttttc ttttttgaga cggagtctcg ctctgccgcc 3000

 caggctggag tgcagtggcg cgatctcggc tcactgcaag ctctgcctcc 3050

 caggttcaca ccattctcct gcctcagcct cccgagtagc tgggactaca 3100

 ggtgcccacc accacgcctg gctagttttt tgtattttta gtagagacgc 3150

 agtttcaccg tgttagccag gatggtctcg atctcctgac cttgtgatct 3200

 gcccgcctcg gcctcccaaa gtgctgggat tacaggcgtg agccaccgcg 3250

 cccagcctac attcacttct aaagtctatg taatggtggt cattttttcc 3300

 cttttagaat acattaaatg gttgatttgg ggaggaaaac ttattctgaa 3350

 tattaacggt ggtgaaaagg ggacagtttt taccctaaag tgcaaaagtg 3400

 aaacatacaa aataagacta atttttaaga gtaactcagt aatttcaaaa 3450

 tacagatttg aatagcagca ttagtggttt gagtgtctag caaaggaaaa 3500

 attgatgaat aaaatgaagg tctggtgtat atgttttaaa atactctcat 3550

 atagtcacac tttaaattaa gccttatatt aggcccctct attttcagga 3600

 tataattctt aactatcatt atttacctga ttttaatcat cagattcgaa 3650

 attctgtgcc atggcgtata tgttcaaatt caaaccattt ttaaaatgtg 3700

 aagatggact tcatgcaagt tggcagtggt tctggtacta aaaattgtgg 3750

 ttgttttttc tgtttacgta acctgcttag tattgacact ctctaccaag 3800

 agggtcttcc taagaagagt gctgtcatta tttcctctta tcaacaactt 3850

 gtgacatgag attttttaag ggctttatgt gaactatgat attgtaattt 3900

 ttctaagcat attcaaaagg gtgacaaaat tacgtttatg tactaaatct 3950

 aatcaggaaa gtaaggcagg aaaagttgat ggtattcatt aggttttaac 4000

 tgaatggagc agttccttat ataataacaa ttgtatagta gggataaaac 4050

 actaacttaa tgtgtattca ttttaaattg ttctgtattt ttaaattgcc 4100

 aagaaaaaca actttgtaaa tttggagata ttttccaaca gcttttcgtc 4150

 ttcagtgtct taatgtggaa gttaaccctt accaaaaaag gaagttggca 4200

 aaaacagcct tctagcacac ttttttaaat gaataatggt agcctaaact 4250

 taatattttt ataaagtatt gtaatattgt tttgtggata attgaaataa 4300

 aaagttctca ttgaatgcac ctattaaaaa aaaaaaaaaa aaa 4343

<210> 5674
<211> 543
<212> PRT
<213> Homo sapien

<400> 5674
 Met Gly Cys Ile Lys Ser Lys Glu Asn Lys Ser Pro Ala Ile Lys
   1               5                  10                  15

 Tyr Arg Pro Glu Asn Thr Pro Glu Pro Val Ser Thr Ser Val Ser
                  20                  25                  30

 His Tyr Gly Ala Glu Pro Thr Thr Val Ser Pro Cys Pro Ser Ser
                  35                  40                  45

 Ser Ala Lys Gly Thr Ala Val Asn Phe Ser Ser Leu Ser Met Thr
                  50                  55                  60

 Pro Phe Gly Gly Ser Ser Gly Val Thr Pro Phe Gly Gly Ala Ser
                  65                  70                  75

 Ser Ser Phe Ser Val Val Pro Ser Ser Tyr Pro Ala Gly Leu Thr
                  80                  85                  90

 Gly Gly Val Thr Ile Phe Val Ala Leu Tyr Asp Tyr Glu Ala Arg
                  95                 100                 105

 Thr Thr Glu Asp Leu Ser Phe Lys Lys Gly Glu Arg Phe Gln Ile
                 110                 115                 120

 Ile Asn Asn Thr Glu Gly Asp Trp Trp Glu Ala Arg Ser Ile Ala
                 125                 130                 135

 Thr Gly Lys Asn Gly Tyr Ile Pro Ser Asn Tyr Val Ala Pro Ala
                 140                 145                 150

 Asp Ser Ile Gln Ala Glu Glu Trp Tyr Phe Gly Lys Met Gly Arg
                 155                 160                 165

 Lys Asp Ala Glu Arg Leu Leu Leu Asn Pro Gly Asn Gln Arg Gly
                 170                 175                 180

 Ile Phe Leu Val Arg Glu Ser Glu Thr Thr Lys Gly Ala Tyr Ser
                 185                 190                 195

 Leu Ser Ile Arg Asp Trp Asp Glu Ile Arg Gly Asp Asn Val Lys
                 200                 205                 210

 His Tyr Lys Ile Arg Lys Leu Asp Asn Gly Gly Tyr Tyr Ile Thr
                 215                 220                 225

 Thr Arg Ala Gln Phe Asp Thr Leu Gln Lys Leu Val Lys His Tyr
                 230                 235                 240

 Thr Glu His Ala Asp Gly Leu Cys His Lys Leu Thr Thr Val Cys
                 245                 250                 255

 Pro Thr Val Lys Pro Gln Thr Gln Gly Leu Ala Lys Asp Ala Trp
                 260                 265                 270

 Glu Ile Pro Arg Glu Ser Leu Arg Leu Glu Val Lys Leu Gly Gln
                 275                 280                 285

 Gly Cys Phe Gly Glu Val Trp Met Gly Thr Trp Asn Gly Thr Thr
                 290                 295                 300

 Lys Val Ala Ile Lys Thr Leu Lys Pro Gly Thr Met Met Pro Glu
                 305                 310                 315

 Ala Phe Leu Gln Glu Ala Gln Ile Met Lys Lys Leu Arg His Asp
                 320                 325                 330

 Lys Leu Val Pro Leu Tyr Ala Val Val Ser Glu Glu Pro Ile Tyr
                 335                 340                 345

 Ile Val Thr Glu Phe Met Ser Lys Gly Ser Leu Leu Asp Phe Leu
                 350                 355                 360

 Lys Glu Gly Asp Gly Lys Tyr Leu Lys Leu Pro Gln Leu Val Asp
                 365                 370                 375

 Met Ala Ala Gln Ile Ala Asp Gly Met Ala Tyr Ile Glu Arg Met
                 380                 385                 390

 Asn Tyr Ile His Arg Asp Leu Arg Ala Ala Asn Ile Leu Val Gly
                 395                 400                 405

 Glu Asn Leu Val Cys Lys Ile Ala Asp Phe Gly Leu Ala Arg Leu
                 410                 415                 420

 Ile Glu Asp Asn Glu Tyr Thr Ala Arg Gln Gly Ala Lys Phe Pro
                 425                 430                 435

 Ile Lys Trp Thr Ala Pro Glu Ala Ala Leu Tyr Gly Arg Phe Thr
                 440                 445                 450

 Ile Lys Ser Asp Val Trp Ser Phe Gly Ile Leu Gln Thr Glu Leu
                 455                 460                 465

 Val Thr Lys Gly Arg Val Pro Tyr Pro Gly Met Val Asn Arg Glu
                 470                 475                 480

 Val Leu Glu Gln Val Glu Arg Gly Tyr Arg Met Pro Cys Pro Gln
                 485                 490                 495

 Gly Cys Pro Glu Ser Leu His Glu Leu Met Asn Leu Cys Trp Lys
                 500                 505                 510

 Lys Asp Pro Asp Glu Arg Pro Thr Phe Glu Tyr Ile Gln Ser Phe
                 515                 520                 525

 Leu Glu Asp Tyr Phe Thr Ala Thr Glu Pro Gln Tyr Gln Pro Gly
                 530                 535                 540

 Glu Asn Leu


<210> 5675
<211> 2214
<212> DNA
<213> Homo sapien

<400> 5675
 gttgactgga ggcggaggtt gcagtgagcc gagatcgccc cactgcactc 50

 cagcctggtg actccgtctc aaaaaaaagg ggaggggggc gggggagagt 100

 tgaaagctta atatgtactt tgggggctat taaagcaaac atttcgacta 150

 aaggggcgaa tcctcgaatt gtgcgatcaa gcacccgaga ggagagttgg 200

 ggggggtcag gaggggtggg ggctccaggg aacgcccggg ggcctgggcc 250

 ggggtctcgc ggggcccttc cggaaggatc gcggcccccg aaggtgggcg 300

 tcccgcgggg ctccagtctc caggacgttc cgggaggctc cgcgctctgg 350

 gaggccggct gcgtggggtc cccgcgctgc agccgcagag gccccccagg 400

 gccgcggttc ccggagcggg aaagtcccgc gcgggggcgg tggcctcggg 450

 ggcgggacgg ggcgggggcg ggggcgcggg cggccgagcc gaatcccctc 500

 caccgggacg ccccgctgcc gctcgggaag aggcgggccc tgcgcgccct 550

 gcgctcgcca tggcggtttg ggcggcgacg tgagcggctc cgcggacccc 600

 gagcggggcc ccggccgcga cctgagccgc cgccgagcgc ccggggccat 650

 gcgaccgacg ctgctgtggt cgctgctgct gctgctcgga gtcttcgccg 700

 ccgccgccgc ggccccgcca gaccctcttt cccagctgcc cgctcctcag 750

 cacccgaaga ttcgcctgta caacgcagag caggtcctga gttgggagcc 800

 agtggccctg agcaatagca cgaggcctgt tgtctaccga gtgcagttta 850

 aatacaccga cagtaaatgg ttcacggccg acatcatgtc cataggggtg 900

 aattgtacac agatcacagc aacagagtgt gacttcactg ccgccagtcc 950

 ctcagcaggc ttcccaatgg atttcaatgt cactctacgc cttcgagctg 1000

 agctgggagc actccattct gcctgggtga caatgccttg gtttcaacac 1050

 tatcggaatg tgactgtcgg gcctccagaa aacattgagg tgaccccagg 1100

 agaaggctcc ctcatcatca ggttctcctc tccctttgac atcgctgata 1150

 cctccacggc ctttttttgt tattatgtcc attactggga aaaaggagga 1200

 atccaacagg tcaaaggccc tttcagaagc aactccattt cattggataa 1250

 cttaaaaccc tccagagtgt actgtttaca agtccaggca caactgcttt 1300

 ggaacaaaag taacatcttt agagtcgggc atttaagcaa catatcttgc 1350

 tacgaaacaa tggcagatgc ctccactgag cttcagcaag tcatcctgat 1400

 ctccgtggga acattttcgt tgctgtcggt gctggcagga gcctgtttct 1450

 tcctggtcct gaaatataga ggcctgatta aatactggtt tcacactcca 1500

 ccaagcatcc cattacagat agaagagtat ttaaaagacc caactcagcc 1550

 catcttagag gccttggaca aggacagctc accaaaggat gacgtctggg 1600

 actctgtgtc cattatctcg tttccggaaa aggagcaaga agatgttctc 1650

 caaacgcttt gaaccaaagc atgggcctag cccactggct ccctggaaga 1700

 gatcaagcca tcggagctgc tagagttctg tctggacttt ccagagacca 1750

 gtattccctt ttgctgcctc taaaaggcct gtccctgcag acatgagaga 1800

 cagcaggtct catgggggtg acaagctttt tttttttttt cttaaagaat 1850

 tttcaaaatc aaattccaga atgattttac ggagatatcc caggaaaatt 1900

 aaggcttctc ttaaacacta aaaaggcatg taattgcttg ttagcaaaat 1950

 ggatatgaca catctctgat acttttttca ttattggttg ggctgagcag 2000

 tcagaagacc tggtcgtcgt cttgactttg gcaaatgagc cggagcccct 2050

 tgggcaggtc acacaacctg tcccagcgag ggacactgag tggcccttca 2100

 tgtacatcca tggtgtgctg gcttaaaatg taattaatct tgtaaatata 2150

 ctcctagtaa tttaagattt tgtttttaaa ctggaaataa aagattgtat 2200

 agtgcatgtt tttt 2214

<210> 5676
<211> 337
<212> PRT
<213> Homo sapien

<400> 5676
 Met Arg Pro Thr Leu Leu Trp Ser Leu Leu Leu Leu Leu Gly Val
   1               5                  10                  15

 Phe Ala Ala Ala Ala Ala Ala Pro Pro Asp Pro Leu Ser Gln Leu
                  20                  25                  30

 Pro Ala Pro Gln His Pro Lys Ile Arg Leu Tyr Asn Ala Glu Gln
                  35                  40                  45

 Val Leu Ser Trp Glu Pro Val Ala Leu Ser Asn Ser Thr Arg Pro
                  50                  55                  60

 Val Val Tyr Arg Val Gln Phe Lys Tyr Thr Asp Ser Lys Trp Phe
                  65                  70                  75

 Thr Ala Asp Ile Met Ser Ile Gly Val Asn Cys Thr Gln Ile Thr
                  80                  85                  90

 Ala Thr Glu Cys Asp Phe Thr Ala Ala Ser Pro Ser Ala Gly Phe
                  95                 100                 105

 Pro Met Asp Phe Asn Val Thr Leu Arg Leu Arg Ala Glu Leu Gly
                 110                 115                 120

 Ala Leu His Ser Ala Trp Val Thr Met Pro Trp Phe Gln His Tyr
                 125                 130                 135

 Arg Asn Val Thr Val Gly Pro Pro Glu Asn Ile Glu Val Thr Pro
                 140                 145                 150

 Gly Glu Gly Ser Leu Ile Ile Arg Phe Ser Ser Pro Phe Asp Ile
                 155                 160                 165

 Ala Asp Thr Ser Thr Ala Phe Phe Cys Tyr Tyr Val His Tyr Trp
                 170                 175                 180

 Glu Lys Gly Gly Ile Gln Gln Val Lys Gly Pro Phe Arg Ser Asn
                 185                 190                 195

 Ser Ile Ser Leu Asp Asn Leu Lys Pro Ser Arg Val Tyr Cys Leu
                 200                 205                 210

 Gln Val Gln Ala Gln Leu Leu Trp Asn Lys Ser Asn Ile Phe Arg
                 215                 220                 225

 Val Gly His Leu Ser Asn Ile Ser Cys Tyr Glu Thr Met Ala Asp
                 230                 235                 240

 Ala Ser Thr Glu Leu Gln Gln Val Ile Leu Ile Ser Val Gly Thr
                 245                 250                 255

 Phe Ser Leu Leu Ser Val Leu Ala Gly Ala Cys Phe Phe Leu Val
                 260                 265                 270

 Leu Lys Tyr Arg Gly Leu Ile Lys Tyr Trp Phe His Thr Pro Pro
                 275                 280                 285

 Ser Ile Pro Leu Gln Ile Glu Glu Tyr Leu Lys Asp Pro Thr Gln
                 290                 295                 300

 Pro Ile Leu Glu Ala Leu Asp Lys Asp Ser Ser Pro Lys Asp Asp
                 305                 310                 315

 Val Trp Asp Ser Val Ser Ile Ile Ser Phe Pro Glu Lys Glu Gln
                 320                 325                 330

 Glu Asp Val Leu Gln Thr Leu
                 335

<210> 5677
<211> 1436
<212> DNA
<213> Homo sapien

<400> 5677
 agtgtggtca ggcggctcgg actgagcagg actttcctta tcccagttga 50

 ttgtgcagaa tacactgcct atcgcttgtc ttctattcac catggcttct 100

 tctgatatcc aggtgaaaga actggagaag cgtgcctcag gccaggcttt 150

 tgagctgatt ctcagccctc ggtcaaaaga atctgttcca gaattccccc 200

 tttcccctcc aaagaagaag gatctttccc tggaggaaat tcagaagaaa 250

 ttagaagctg cagaagaaag acgcaagtcc catgaagctg aggtcttgaa 300

 gcagctggct gagaaacgag agcacgagaa agaagtgctt cagaaggcaa 350

 tagaagagaa caacaacttc agtaaaatgg cagaagagaa actgacccac 400

 aaaatggaag ctaataaaga gaaccgagag gcacaaatgg ctgccaaact 450

 ggaacgtttg cgagagaagg ataagcacat tgaagaagtg cggaagaaca 500

 aagaatccaa agaccctgct gacgagactg aagctgacta atttgttctg 550

 agaactgact ttctccccat ccccttccta aatatccaaa gactgtactg 600

 gccagtgtca ttttattttt tccctcctga caaatatttt agaagctaat 650

 gtaggactgt ataggtagat ccagatccag actgtaagat gttgttttag 700

 gggctaaagg ggagaaactg aaagtgtttt actctttttc taaagtgttg 750

 gtctttctaa tgtagctatt tttcttgttg catcttttct acttcagtac 800

 acttggtgta ctgggttaat ggctagtact gtattggctc tgtgaaaaca 850

 tatttgtgaa aagagtatgt agtggcttct tttgaactgt tagatgctga 900

 atatctgttc acttttcaat cccaattctg tcccaatctt accagatgct 950

 actggacttg aatggttaat aaaactgcac agtgctgttg gtggcagtga 1000

 cttcttttga gttaggttaa taaatcaagc catagagccc ctcctggttg 1050

 atacttgttc cagatggggc ctttggggct ggtagaaata cccaacgcac 1100

 aaatgaccgc acgttctctg ccccgtttct tgccccagtg tggtttgcat 1150

 tgtctccttc cacaatgact gctttgtttg gatgcctcag cccaggtcag 1200

 ctgttacttt ctttcagatg tttatttgca aacaaccatt ttttgttctg 1250

 tgtccctttt aaaaggcaga ttaaaagcac aagcgtgttt ctagagaaca 1300

 gttgagagag aatctcaaga ttctacttgg tggtttgctt gctctacgtt 1350

 acaggtgggg catgtcctca tcctttcctg ccataaaagc tatgacacga 1400

 gaatcagaat attaataaaa ctttatgtac tgctgt 1436

<210> 5678
<211> 149
<212> PRT
<213> Homo sapien

<400> 5678
 Met Ala Ser Ser Asp Ile Gln Val Lys Glu Leu Glu Lys Arg Ala
   1               5                  10                  15

 Ser Gly Gln Ala Phe Glu Leu Ile Leu Ser Pro Arg Ser Lys Glu
                  20                  25                  30

 Ser Val Pro Glu Phe Pro Leu Ser Pro Pro Lys Lys Lys Asp Leu
                  35                  40                  45

 Ser Leu Glu Glu Ile Gln Lys Lys Leu Glu Ala Ala Glu Glu Arg
                  50                  55                  60

 Arg Lys Ser His Glu Ala Glu Val Leu Lys Gln Leu Ala Glu Lys
                  65                  70                  75

 Arg Glu His Glu Lys Glu Val Leu Gln Lys Ala Ile Glu Glu Asn
                  80                  85                  90

 Asn Asn Phe Ser Lys Met Ala Glu Glu Lys Leu Thr His Lys Met
                  95                 100                 105

 Glu Ala Asn Lys Glu Asn Arg Glu Ala Gln Met Ala Ala Lys Leu
                 110                 115                 120

 Glu Arg Leu Arg Glu Lys Asp Lys His Ile Glu Glu Val Arg Lys
                 125                 130                 135

 Asn Lys Glu Ser Lys Asp Pro Ala Asp Glu Thr Glu Ala Asp
                 140                 145

<210> 5679
<211> 783
<212> DNA
<213> Homo sapien

<400> 5679
 cccaggagtc tgggtgcaca gcctccttct ctctgagatt caagagtctg 50

 atcagcagcc tcttcctcct ccaggaccca gaagccctga gcttatcccc 100

 atggagctct gccggtccct ggccctgctg gggggctccc tgggcctgat 150

 gttctgcctg attgctttga gcaccgattt ctggtttgag gctgtgggtc 200

 ccacccactc agctcactcg ggcctctggc caacagggca tggggacatc 250

 atatcaggct acatccacgt gacgcagacc ttcagcatta tggctgttct 300

 gtgggccctg gtgtccgtga gcttcctggt cctgtcctgc ttcccctcac 350

 tgttcccccc aggccacggc ccgcttgtct caaccaccgc agcctttgct 400

 gcagccatct ccatggtggt ggccatggcg gtgtacacca gcgagcggtg 450

 ggaccagcct ccacaccccc agatccagac cttcttctcc tggtccttct 500

 acctgggctg ggtctcagct atcctcttgc tctgtacagg tgccctgagc 550

 ctgggtgctc actgtggcgg tccccgtcct ggctatgaaa ccttgtgagc 600

 agaaggcaag agcggcaaga tgagttttga gcgttgtatt ccaaaggcct 650

 catctggagc ctcgggaaag tctggtccta catttgcccg cccttccagc 700

 ccttccccag cccctcctct tgtttcttca ttcattcaac aaaatttggc 750

 tggaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 783

<210> 5680
<211> 165
<212> PRT
<213> Homo sapien

<400> 5680
 Met Glu Leu Cys Arg Ser Leu Ala Leu Leu Gly Gly Ser Leu Gly
   1               5                  10                  15

 Leu Met Phe Cys Leu Ile Ala Leu Ser Thr Asp Phe Trp Phe Glu
                  20                  25                  30

 Ala Val Gly Pro Thr His Ser Ala His Ser Gly Leu Trp Pro Thr
                  35                  40                  45

 Gly His Gly Asp Ile Ile Ser Gly Tyr Ile His Val Thr Gln Thr
                  50                  55                  60

 Phe Ser Ile Met Ala Val Leu Trp Ala Leu Val Ser Val Ser Phe
                  65                  70                  75

 Leu Val Leu Ser Cys Phe Pro Ser Leu Phe Pro Pro Gly His Gly
                  80                  85                  90

 Pro Leu Val Ser Thr Thr Ala Ala Phe Ala Ala Ala Ile Ser Met
                  95                 100                 105

 Val Val Ala Met Ala Val Tyr Thr Ser Glu Arg Trp Asp Gln Pro
                 110                 115                 120

 Pro His Pro Gln Ile Gln Thr Phe Phe Ser Trp Ser Phe Tyr Leu
                 125                 130                 135

 Gly Trp Val Ser Ala Ile Leu Leu Leu Cys Thr Gly Ala Leu Ser
                 140                 145                 150

 Leu Gly Ala His Cys Gly Gly Pro Arg Pro Gly Tyr Glu Thr Leu
                 155                 160                 165

<210> 5681
<211> 916
<212> DNA
<213> Homo sapien

<400> 5681
 acttctcgct cgacacagcc agagctggag gtgggtgccc ggcacggagg 50

 ggcctgcgga ccaatggctc tgccctgcac cttagggctc gggatgctgc 100

 tggccctgcc aggggccttg ggctcgggtg gcagcgcgga ggacagcgtg 150

 ggctccagct ctgtcaccgt tgtcctgctg ctgctgctgc tcctactgct 200

 ggccactggc ctagcactgg cctggcgccg cctcagccgt gactcagggg 250

 gctactacca cccggcccgc ctaggtgccg cgctgtgggg ccgcacgcgg 300

 cgcctgctct gggccagccc cccaggtcgc tggctgcagg cccgagctga 350

 gctggggtcc acagacaatg accttgagcg acaggaggat gagcaggaca 400

 cagactatga ccacgtcgcg gatggtggcc tgcaggctga ccctggggaa 450

 ggcgagcagc aatgtggaga ggcgtccagc ccagagcagg tccccgtgcg 500

 ggctgaggaa gccagagaca gtgacacgga gggcgacctg gtcctcggct 550

 ccccaggacc agcgagcgca gggggcagtg ctgaggccct gctgagtgac 600

 ctgcacgcct ttgctggcag cgcagcctgg gatgacagcg ccagggcagc 650

 tgggggccag ggcctccatg tcaccgcact gtagaggccg gtcttggtgt 700

 cccatccctg tcacagccgc tcactccccg tgcctctgct tcccaagatg 750

 ccatggctgg actggacccc cagcccacat gaccatgcct cagactgtca 800

 cccctaccag ttcccaagtc catgtgtacc ccgctcacca cgggaacggc 850

 cccccccaac cacaggcatc aggcaaccat ttgaaataaa actccttcag 900

 cctgtgaaaa aaaaaa 916

<210> 5682
<211> 206
<212> PRT
<213> Homo sapien

<400> 5682
 Met Ala Leu Pro Cys Thr Leu Gly Leu Gly Met Leu Leu Ala Leu
   1               5                  10                  15

 Pro Gly Ala Leu Gly Ser Gly Gly Ser Ala Glu Asp Ser Val Gly
                  20                  25                  30

 Ser Ser Ser Val Thr Val Val Leu Leu Leu Leu Leu Leu Leu Leu
                  35                  40                  45

 Leu Ala Thr Gly Leu Ala Leu Ala Trp Arg Arg Leu Ser Arg Asp
                  50                  55                  60

 Ser Gly Gly Tyr Tyr His Pro Ala Arg Leu Gly Ala Ala Leu Trp
                  65                  70                  75

 Gly Arg Thr Arg Arg Leu Leu Trp Ala Ser Pro Pro Gly Arg Trp
                  80                  85                  90

 Leu Gln Ala Arg Ala Glu Leu Gly Ser Thr Asp Asn Asp Leu Glu
                  95                 100                 105

 Arg Gln Glu Asp Glu Gln Asp Thr Asp Tyr Asp His Val Ala Asp
                 110                 115                 120

 Gly Gly Leu Gln Ala Asp Pro Gly Glu Gly Glu Gln Gln Cys Gly
                 125                 130                 135

 Glu Ala Ser Ser Pro Glu Gln Val Pro Val Arg Ala Glu Glu Ala
                 140                 145                 150

 Arg Asp Ser Asp Thr Glu Gly Asp Leu Val Leu Gly Ser Pro Gly
                 155                 160                 165

 Pro Ala Ser Ala Gly Gly Ser Ala Glu Ala Leu Leu Ser Asp Leu
                 170                 175                 180

 His Ala Phe Ala Gly Ser Ala Ala Trp Asp Asp Ser Ala Arg Ala
                 185                 190                 195

 Ala Gly Gly Gln Gly Leu His Val Thr Ala Leu
                 200                 205

<210> 5683
<211> 2386
<212> DNA
<213> Homo sapien

<400> 5683
 agcatacgcc gagccggtct ttgagcgcta acgtctttct gtctccccgc 50

 ggtggtgatg acggtgaaaa ctgaggctgc taagggcacc ctcacttact 100

 ccaggatgag gggcatggtg gcaattctca tcgctttcat gaagcagagg 150

 aggatgggtc tgaacgactt tattcagaag attgccaata actcctatgc 200

 atgcaaacac cctgaagttc agtccatctt gaagatctcc caacctcagg 250

 agcctgagct tatgaatgcc aacccttctc ctccaccaag tccttctcag 300

 caaatcaacc ttggcccgtc gtccaatcct catgctaaac catctgactt 350

 tcacttcttg aaagtgatcg gaaagggcag ttttggaaag gttcttctag 400

 caagacacaa ggcagaagaa gtgttctatg cagtcaaagt tttacagaag 450

 aaagcaatcc tgaaaaagaa agaggagaag catattatgt cggagcggaa 500

 tgttctgttg aagaatgtga agcacccttt cctggtgggc cttcacttct 550

 ctttccagac tgctgacaaa ttgtactttg tcctagacta cattaatggt 600

 ggagagttgt tctaccatct ccagagggaa cgctgcttcc tggaaccacg 650

 ggctcgtttc tatgctgctg aaatagccag tgccttgggc tacctgcatt 700

 cactgaacat cgtttataga gacttaaaac cagagaatat tttgctagat 750

 tcacagggac acattgtcct tactgacttc ggactctgca aggagaacat 800

 tgaacacaac agcacaacat ccaccttctg tggcacgccg gagtatctcg 850

 cacctgaggt gcttcataag cagccttatg acaggactgt ggactggtgg 900

 tgcctgggag ctgtcttgta tgagatgctg tatggcctgc cgccttttta 950

 tagccgaaac acagctgaaa tgtacgacaa cattctgaac aagcctctcc 1000

 agctgaaacc aaatattaca aattccgcaa gacacctcct ggagggcctc 1050

 ctgcagaagg acaggacaaa gcggctcggg gccaaggatg acttcatgga 1100

 gattaagagt catgtcttct tctccttaat taactgggat gatctcatta 1150

 ataagaagat tactccccct tttaacccaa atgtgagtgg gcccaacgac 1200

 ctacggcact ttgaccccga gtttaccgaa gagcctgtcc ccaactccat 1250

 tggcaagtcc cctgacagcg tcctcgtcac agccagcgtc aaggaagctg 1300

 ccgaggcttt cctaggcttt tcctatgcgc ctcccacgga ctctttcctc 1350

 tgaaccctgt tagggcttgg ttttaaagga ttttatgtgt gtttccgaat 1400

 gttttagtta gccttttggt ggagccgcca gctgacagga catcttacaa 1450

 gagaatttgc acatctctgg aagcttagca atcttattgc acactgttcg 1500

 ctggaagctt tttgaagagc acattctcct cagtgagctc atgaggtttt 1550

 catttttatt cttccttcca acgtggtgct atctctgaaa cgagcgttag 1600

 agtgccgcct tagacggagg caggagtttc gttagaaagc ggacgctgtt 1650

 ctaaaaaagg tctcctgcag atctgtctgg gctgtgatga cgaatattat 1700

 gaaatgtgcc ttttctgaag agattgtgtt agctccaaag cttttcctat 1750

 cgcagtgttt cagttcttta ttttcccttg tggatatgct gtgtgaaccg 1800

 tcgtgtgagt gtggtatgcc tgatcacaga tggattttgt tataagcatc 1850

 aatgtgacac ttgcaggaca ctacaacgtg ggacattgtt tgtttcttcc 1900

 atatttggaa gataaattta tgtgtagact tttttgtaag atacggttaa 1950

 taactaaaat ttattgaaat ggtcttgcaa tgactcgtat tcagatgctt 2000

 aaagaaagca ttgctgctac aaatatttct atttttagaa agggttttta 2050

 tggaccaatg ccccagttgt cagtcagagc cgttggtgtt tttcattgtt 2100

 taaaatgtca cctgtaaaat gggcattatt tatgtttttt tttttgcatt 2150

 cctgataatt gtatgtattg tataaagaac gtctgtacat tgggttataa 2200

 cactagtata tttaaactta caggcttatt tgtaatgtaa accaccattt 2250

 taatgtactg taattaacat ggttataata cgtacaatcc ttccctcatc 2300

 ccatcacaca actttttttg tgtgtgataa actgattttg gtttgcaata 2350

 aaaccttgaa aaatatttac aaaaaaaaaa aaaaaa 2386

<210> 5684
<211> 431
<212> PRT
<213> Homo sapien

<400> 5684
 Met Thr Val Lys Thr Glu Ala Ala Lys Gly Thr Leu Thr Tyr Ser
   1               5                  10                  15

 Arg Met Arg Gly Met Val Ala Ile Leu Ile Ala Phe Met Lys Gln
                  20                  25                  30

 Arg Arg Met Gly Leu Asn Asp Phe Ile Gln Lys Ile Ala Asn Asn
                  35                  40                  45

 Ser Tyr Ala Cys Lys His Pro Glu Val Gln Ser Ile Leu Lys Ile
                  50                  55                  60

 Ser Gln Pro Gln Glu Pro Glu Leu Met Asn Ala Asn Pro Ser Pro
                  65                  70                  75

 Pro Pro Ser Pro Ser Gln Gln Ile Asn Leu Gly Pro Ser Ser Asn
                  80                  85                  90

 Pro His Ala Lys Pro Ser Asp Phe His Phe Leu Lys Val Ile Gly
                  95                 100                 105

 Lys Gly Ser Phe Gly Lys Val Leu Leu Ala Arg His Lys Ala Glu
                 110                 115                 120

 Glu Val Phe Tyr Ala Val Lys Val Leu Gln Lys Lys Ala Ile Leu
                 125                 130                 135

 Lys Lys Lys Glu Glu Lys His Ile Met Ser Glu Arg Asn Val Leu
                 140                 145                 150

 Leu Lys Asn Val Lys His Pro Phe Leu Val Gly Leu His Phe Ser
                 155                 160                 165

 Phe Gln Thr Ala Asp Lys Leu Tyr Phe Val Leu Asp Tyr Ile Asn
                 170                 175                 180

 Gly Gly Glu Leu Phe Tyr His Leu Gln Arg Glu Arg Cys Phe Leu
                 185                 190                 195

 Glu Pro Arg Ala Arg Phe Tyr Ala Ala Glu Ile Ala Ser Ala Leu
                 200                 205                 210

 Gly Tyr Leu His Ser Leu Asn Ile Val Tyr Arg Asp Leu Lys Pro
                 215                 220                 225

 Glu Asn Ile Leu Leu Asp Ser Gln Gly His Ile Val Leu Thr Asp
                 230                 235                 240

 Phe Gly Leu Cys Lys Glu Asn Ile Glu His Asn Ser Thr Thr Ser
                 245                 250                 255

 Thr Phe Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val Leu His
                 260                 265                 270

 Lys Gln Pro Tyr Asp Arg Thr Val Asp Trp Trp Cys Leu Gly Ala
                 275                 280                 285

 Val Leu Tyr Glu Met Leu Tyr Gly Leu Pro Pro Phe Tyr Ser Arg
                 290                 295                 300

 Asn Thr Ala Glu Met Tyr Asp Asn Ile Leu Asn Lys Pro Leu Gln
                 305                 310                 315

 Leu Lys Pro Asn Ile Thr Asn Ser Ala Arg His Leu Leu Glu Gly
                 320                 325                 330

 Leu Leu Gln Lys Asp Arg Thr Lys Arg Leu Gly Ala Lys Asp Asp
                 335                 340                 345

 Phe Met Glu Ile Lys Ser His Val Phe Phe Ser Leu Ile Asn Trp
                 350                 355                 360

 Asp Asp Leu Ile Asn Lys Lys Ile Thr Pro Pro Phe Asn Pro Asn
                 365                 370                 375

 Val Ser Gly Pro Asn Asp Leu Arg His Phe Asp Pro Glu Phe Thr
                 380                 385                 390

 Glu Glu Pro Val Pro Asn Ser Ile Gly Lys Ser Pro Asp Ser Val
                 395                 400                 405

 Leu Val Thr Ala Ser Val Lys Glu Ala Ala Glu Ala Phe Leu Gly
                 410                 415                 420

 Phe Ser Tyr Ala Pro Pro Thr Asp Ser Phe Leu
                 425                 430

<210> 5685
<211> 2856
<212> DNA
<213> Homo sapien

<400> 5685
 gtaaccgcta ctcccggaca ccagaccacc gccttccgta cacaggggcc 50

 cgcatcccac cctcccggac ctaagagcct gggtcccctg tttccggagg 100

 tccgcttccc ggcccccaga ttctggcatc ccagccctca gtgtccaaga 150

 cccaggcagc ccgggtcccc gcctcccgga tccaggcgtc cgggatctgc 200

 gccaccagaa cctagcctcc tgcagacctc cgccatctgg gggcactcaa 250

 cctcctggag ccaagggccc cacgtcccac ccagagaaac tctcgtattc 300

 ccagctccta gggccaagga acccgggcgc tccgaactcc cagctttcgg 350

 acatctggca cacggggcag agcagagaag ctcagcgccc agcctgggga 400

 atttaaacac tccagcttcc aagagccaag gaacttcagt gctgtgaact 450

 cacaactcta aggagccctc caaagttcca gtctccaggt gctgttactc 500

 aactcagtcc taggaacgtc gggtcctggg aaggagccca agcgctccca 550

 gccagcttcc aggcgctaag aaaccccggt gcttcccatc atggtggccg 600

 atcctcctcg agactccaag gggctcgcag cggcggagcc caccgccaac 650

 gggggcctgg cgctggcctc catcgaggac caaggcgcgg cagcaggcgg 700

 ctactgcggt tcccgggacc aggtgcgccg ctgccttcga gccaacctgc 750

 ttgtgctgct gacagtggtg gccgtggtgg ccggcgtggc gctgggactg 800

 ggggtgtcgg gggccggggg tgcgctggcg ttgggcccgg agcgcttgag 850

 cgccttcgtc ttcccgggcg agctgctgct gcgtctgctg cggatgatca 900

 tcttgccgct ggtggtgtgc agcttgatcg gcggcgccgc cagcctggac 950

 cccggcgcgc tcggccgtct gggcgcctgg gcgctgctct ttttcctggt 1000

 caccacgctg ctggcgtcgg cgctcggagt gggcttggcg ctggctctgc 1050

 agccgggcgc cgcctccgcc gccatcaacg cctccgtggg agccgcgggc 1100

 agtgccgaaa atgcccccag caaggaggtg ctcgattcgt tcctggatct 1150

 tgcgagaaat atcttccctt ccaacctggt gtcagcagcc tttcgctcat 1200

 actctaccac ctatgaagag aggaatatca ccggaaccag ggtgaaggtg 1250

 cccgtggggc aggaggtgga ggggatgaac atcctgggct tggtagtgtt 1300

 tgccatcgtc tttggtgtgg cgctgcggaa gctggggcct gaaggggagc 1350

 tgcttatccg cttcttcaac tccttcaatg aggccaccat ggttctggtc 1400

 tcctggatca tgtggtacgc ccctgtgggc atcatgttcc tggtggctgg 1450

 caagatcgtg gagatggagg atgtgggttt actctttgcc cgccttggca 1500

 agtacattct gtgctgcctg ctgggtcacg ccatccatgg gctcctggta 1550

 ctgcccctca tctacttcct cttcacccgc aaaaacccct accgcttcct 1600

 gtggggcatc gtgacgccgc tggccactgc ctttgggacc tcttccagtt 1650

 ccgccacgct gccgctgatg atgaagtgcg tggaggagaa taatggcgtg 1700

 gccaagcaca tcagccgttt catcctgccc atcggcgcca ccgtcaacat 1750

 ggacggtgcc gcgctcttcc agtgcgtggc cgcagtgttc attgcacagc 1800

 tcagccagca gtccttggac ttcgtaaaga tcatcaccat cctggtcacg 1850

 gccacagcgt ccagcgtggg ggcagcgggc atccctgctg gaggtgtcct 1900

 cactctggcc atcatcctcg aagcagtcaa cctcccggtc gaccatatct 1950

 ccttgatcct ggctgtggac tggctagtcg accggtcctg taccgtcctc 2000

 aatgtagaag gtgacgctct gggggcagga ctcctccaaa attatgtgga 2050

 ccgtacggag tcgagaagca cagagcctga gttgatacaa gtgaagagtg 2100

 agctgcccct ggatccgctg ccagtcccca ctgaggaagg aaaccccctc 2150

 ctcaaacact atcgggggcc cgcaggggat gccacggtcg cctctgagaa 2200

 ggaatcagtc atgtaaaccc cgggagggac cttccctgcc ctgctggggg 2250

 tgctctttgg acactggatt atgaggaatg gataaatgga tgagctaggg 2300

 ctctgggggt ctgcctgcac actctgggga gccaggggcc ccagcaccct 2350

 ccaggacagg agatctggga tgcctggctg ctggagtaca tgtgttcaca 2400

 agggttactc ctcaaaaccc ccagttctca ctcatgtccc caactcaagg 2450

 ctagaaaaca gcaagatgga gaaataatgt tctgctgcgt ccccaccgtg 2500

 acctgcctgg cctcccctgt ctcagggagc aggtcacagg tcaccatggg 2550

 gaattctagc ccccactggg gggatgttac aacaccatgc tggttatttt 2600

 ggcggctgta gttgtggggg gatgtgtgtg tgcacgtgtg tgtgtgtgtg 2650

 tgtgtgtgtg tgtgtgtgtg ttctgtgacc tcctgtcccc atggtacgtc 2700

 ccaccctgtc cccagatccc ctattccctc cacaataaca gaaacactcc 2750

 cagggactct ggggagaggc tgaggacaaa tacctgctgt cactccagag 2800

 gacatttttt ttagcaataa aattgagtgt caactattta aaaaaaaaaa 2850

 aaaaaa 2856

<210> 5686
<211> 541
<212> PRT
<213> Homo sapien

<400> 5686
 Met Val Ala Asp Pro Pro Arg Asp Ser Lys Gly Leu Ala Ala Ala
   1               5                  10                  15

 Glu Pro Thr Ala Asn Gly Gly Leu Ala Leu Ala Ser Ile Glu Asp
                  20                  25                  30

 Gln Gly Ala Ala Ala Gly Gly Tyr Cys Gly Ser Arg Asp Gln Val
                  35                  40                  45

 Arg Arg Cys Leu Arg Ala Asn Leu Leu Val Leu Leu Thr Val Val
                  50                  55                  60

 Ala Val Val Ala Gly Val Ala Leu Gly Leu Gly Val Ser Gly Ala
                  65                  70                  75

 Gly Gly Ala Leu Ala Leu Gly Pro Glu Arg Leu Ser Ala Phe Val
                  80                  85                  90

 Phe Pro Gly Glu Leu Leu Leu Arg Leu Leu Arg Met Ile Ile Leu
                  95                 100                 105

 Pro Leu Val Val Cys Ser Leu Ile Gly Gly Ala Ala Ser Leu Asp
                 110                 115                 120

 Pro Gly Ala Leu Gly Arg Leu Gly Ala Trp Ala Leu Leu Phe Phe
                 125                 130                 135

 Leu Val Thr Thr Leu Leu Ala Ser Ala Leu Gly Val Gly Leu Ala
                 140                 145                 150

 Leu Ala Leu Gln Pro Gly Ala Ala Ser Ala Ala Ile Asn Ala Ser
                 155                 160                 165

 Val Gly Ala Ala Gly Ser Ala Glu Asn Ala Pro Ser Lys Glu Val
                 170                 175                 180

 Leu Asp Ser Phe Leu Asp Leu Ala Arg Asn Ile Phe Pro Ser Asn
                 185                 190                 195

 Leu Val Ser Ala Ala Phe Arg Ser Tyr Ser Thr Thr Tyr Glu Glu
                 200                 205                 210

 Arg Asn Ile Thr Gly Thr Arg Val Lys Val Pro Val Gly Gln Glu
                 215                 220                 225

 Val Glu Gly Met Asn Ile Leu Gly Leu Val Val Phe Ala Ile Val
                 230                 235                 240

 Phe Gly Val Ala Leu Arg Lys Leu Gly Pro Glu Gly Glu Leu Leu
                 245                 250                 255

 Ile Arg Phe Phe Asn Ser Phe Asn Glu Ala Thr Met Val Leu Val
                 260                 265                 270

 Ser Trp Ile Met Trp Tyr Ala Pro Val Gly Ile Met Phe Leu Val
                 275                 280                 285

 Ala Gly Lys Ile Val Glu Met Glu Asp Val Gly Leu Leu Phe Ala
                 290                 295                 300

 Arg Leu Gly Lys Tyr Ile Leu Cys Cys Leu Leu Gly His Ala Ile
                 305                 310                 315

 His Gly Leu Leu Val Leu Pro Leu Ile Tyr Phe Leu Phe Thr Arg
                 320                 325                 330

 Lys Asn Pro Tyr Arg Phe Leu Trp Gly Ile Val Thr Pro Leu Ala
                 335                 340                 345

 Thr Ala Phe Gly Thr Ser Ser Ser Ser Ala Thr Leu Pro Leu Met
                 350                 355                 360

 Met Lys Cys Val Glu Glu Asn Asn Gly Val Ala Lys His Ile Ser
                 365                 370                 375

 Arg Phe Ile Leu Pro Ile Gly Ala Thr Val Asn Met Asp Gly Ala
                 380                 385                 390

 Ala Leu Phe Gln Cys Val Ala Ala Val Phe Ile Ala Gln Leu Ser
                 395                 400                 405

 Gln Gln Ser Leu Asp Phe Val Lys Ile Ile Thr Ile Leu Val Thr
                 410                 415                 420

 Ala Thr Ala Ser Ser Val Gly Ala Ala Gly Ile Pro Ala Gly Gly
                 425                 430                 435

 Val Leu Thr Leu Ala Ile Ile Leu Glu Ala Val Asn Leu Pro Val
                 440                 445                 450

 Asp His Ile Ser Leu Ile Leu Ala Val Asp Trp Leu Val Asp Arg
                 455                 460                 465

 Ser Cys Thr Val Leu Asn Val Glu Gly Asp Ala Leu Gly Ala Gly
                 470                 475                 480

 Leu Leu Gln Asn Tyr Val Asp Arg Thr Glu Ser Arg Ser Thr Glu
                 485                 490                 495

 Pro Glu Leu Ile Gln Val Lys Ser Glu Leu Pro Leu Asp Pro Leu
                 500                 505                 510

 Pro Val Pro Thr Glu Glu Gly Asn Pro Leu Leu Lys His Tyr Arg
                 515                 520                 525

 Gly Pro Ala Gly Asp Ala Thr Val Ala Ser Glu Lys Glu Ser Val
                 530                 535                 540

 Met


<210> 5687
<211> 2412
<212> DNA
<213> Homo sapien

<400> 5687
 caggccagga ctccacaagg ctggtcccct gccctggagc aacttaaaca 50

 ggccctctgg ccagcctgga accctgagat ggcctccagc tcaggcagca 100

 gtcctcgccc ggcccctgat gagaatgagt ttccctttgg gtgccctccc 150

 accgtctgcc aggacccaaa ggagcccagg gctctctgct gtgcaggctg 200

 tctctctgag aacccgagga atggcgagga tcagatctgc cccaaatgca 250

 gaggggaaga cctccagtct ataagcccag gaagccgtct tcgaactcag 300

 gagaaggctc accccgaggt ggctgaggct ggaattgggt gcccctttgc 350

 aggtgtcggc tgctccttca agggaagccc acagtctgtg caagagcatg 400

 aggtcacctc ccagacctcc cacctaaacc tgctgttggg gttcatgaaa 450

 cagtggaagg cccggctggg ctgtggcctg gagtctgggc ccatggccct 500

 ggagcagaac ctgtcagacc tgcagctgca ggcagccgtg gaagtggcgg 550

 gggacctgga ggtcgattgc taccgggcac cctgctccga gagccaggag 600

 gagctggccc tgcagcactt catgaaggag aagcttctgg ctgagctgga 650

 ggggaagctg cgtgtgtttg agaacattgt tgctgtcctc aacaaggagg 700

 tggaggcctc ccacctggcc ctggccacct ctatccacca gagccagctg 750

 gaccgtgagc gcatcctgag cttggagcag agggtggtgg agcttcagca 800

 gaccctggcc cagaaagacc aggccctggg caagctggag cagagcttgc 850

 gcctcatgga ggaggcctcc ttcgatggca ctttcctgtg gaagatcacc 900

 aatgtcacca ggcggtgcca tgagtcggcc tgtggcagga ccgtcagcct 950

 cttctcccca gccttctaca ctgccaagta tggctacaag ttgtgcctgc 1000

 ggctgtacct gaatggagat ggcactggaa agagaaccca tctgtcgctc 1050

 ttcatcgtga tcatgagagg ggagtatgat gcgctgctgc cgtggccttt 1100

 ccggaacaag gtcaccttca tgctgctgga ccagaacaac cgtgagcacg 1150

 ccattgacgc cttccggcct gacctaagct cagcgtcctt ccagaggccc 1200

 cagagtgaaa ccaacgtggc cagtggatgc ccactcttct tccccctcag 1250

 caaactgcag tcacccaagc acgcctacgt gaaggacgac acaatgttcc 1300

 tcaagtgcat tgtggagacc agcacttagg gtgggcgggg ctcctgaggg 1350

 agctccaact cagaagggag ctagccagag gactgtgatg ccctgccctt 1400

 ggcacccaag acctcagggc acaaagatgg gtgaaggctg gcatgatcca 1450

 agcaagactg aggggtcgac ttcgggctgg ccatctggtt aggatggcag 1500

 gacgtgggct gggcccacaa aggcaaaggg tccagaagga gacaggcaga 1550

 gctgctcccc tctgcacgga ccatgcgaca ctgggaggcc agtgagccac 1600

 tccggccccg aatgttgagg tggactctca ccaaatgaga agaaaatgga 1650

 accaggcttg gaaccgtagg acccaagcag agaagctctc gggctaggaa 1700

 gatctctgca gggccgccag ggagacctgg acacaggcct gctctctttt 1750

 tctccagggt cagaaacagg accgggtgga agggatgggg tgccagtttg 1800

 aatgcagtct gtccaggctc gtcattggag gtgaacaagc aaacccagag 1850

 ggctccacta ggacttcaaa ttgggggttg gatttgaaga cttttaagtt 1900

 tccttccagc ccagaaagtc tctcattcta ggcctcctgg cccaggtgag 1950

 tcctagagct acaggggttc tggaaacatt caggagcttc ctgtcctccc 2000

 agctcctcac tcaccttcag taacccccac tggactgacc tggtccacag 2050

 ggcacctgcc accctgggcc tggcagctca gcttccccaa cacgcaggag 2100

 cacacccagc ccccacatcc tgtgcctcca tcagctaaac accacgtcac 2150

 ttcatgcagg tgaaacccag tcactgtgag ctcccaggtg cagccagagg 2200

 cacctcaaga agaagagggg cataaacttt cctcttcctg cctagaggcc 2250

 ccacctttgg tgctttccag aatcccgtaa cacctgatta actgaggcat 2300

 ccacttcttt cagcagactg atcaggacct ccaagccact gagcaatgta 2350

 taaccccaaa gaaataattt ttagaatctc tttcgaagtt ttcctaaaaa 2400

 aaaaaaaaaa aa 2412

<210> 5688
<211> 416
<212> PRT
<213> Homo sapien

<400> 5688
 Met Ala Ser Ser Ser Gly Ser Ser Pro Arg Pro Ala Pro Asp Glu
   1               5                  10                  15

 Asn Glu Phe Pro Phe Gly Cys Pro Pro Thr Val Cys Gln Asp Pro
                  20                  25                  30

 Lys Glu Pro Arg Ala Leu Cys Cys Ala Gly Cys Leu Ser Glu Asn
                  35                  40                  45

 Pro Arg Asn Gly Glu Asp Gln Ile Cys Pro Lys Cys Arg Gly Glu
                  50                  55                  60

 Asp Leu Gln Ser Ile Ser Pro Gly Ser Arg Leu Arg Thr Gln Glu
                  65                  70                  75

 Lys Ala His Pro Glu Val Ala Glu Ala Gly Ile Gly Cys Pro Phe
                  80                  85                  90

 Ala Gly Val Gly Cys Ser Phe Lys Gly Ser Pro Gln Ser Val Gln
                  95                 100                 105

 Glu His Glu Val Thr Ser Gln Thr Ser His Leu Asn Leu Leu Leu
                 110                 115                 120

 Gly Phe Met Lys Gln Trp Lys Ala Arg Leu Gly Cys Gly Leu Glu
                 125                 130                 135

 Ser Gly Pro Met Ala Leu Glu Gln Asn Leu Ser Asp Leu Gln Leu
                 140                 145                 150

 Gln Ala Ala Val Glu Val Ala Gly Asp Leu Glu Val Asp Cys Tyr
                 155                 160                 165

 Arg Ala Pro Cys Ser Glu Ser Gln Glu Glu Leu Ala Leu Gln His
                 170                 175                 180

 Phe Met Lys Glu Lys Leu Leu Ala Glu Leu Glu Gly Lys Leu Arg
                 185                 190                 195

 Val Phe Glu Asn Ile Val Ala Val Leu Asn Lys Glu Val Glu Ala
                 200                 205                 210

 Ser His Leu Ala Leu Ala Thr Ser Ile His Gln Ser Gln Leu Asp
                 215                 220                 225

 Arg Glu Arg Ile Leu Ser Leu Glu Gln Arg Val Val Glu Leu Gln
                 230                 235                 240

 Gln Thr Leu Ala Gln Lys Asp Gln Ala Leu Gly Lys Leu Glu Gln
                 245                 250                 255

 Ser Leu Arg Leu Met Glu Glu Ala Ser Phe Asp Gly Thr Phe Leu
                 260                 265                 270

 Trp Lys Ile Thr Asn Val Thr Arg Arg Cys His Glu Ser Ala Cys
                 275                 280                 285

 Gly Arg Thr Val Ser Leu Phe Ser Pro Ala Phe Tyr Thr Ala Lys
                 290                 295                 300

 Tyr Gly Tyr Lys Leu Cys Leu Arg Leu Tyr Leu Asn Gly Asp Gly
                 305                 310                 315

 Thr Gly Lys Arg Thr His Leu Ser Leu Phe Ile Val Ile Met Arg
                 320                 325                 330

 Gly Glu Tyr Asp Ala Leu Leu Pro Trp Pro Phe Arg Asn Lys Val
                 335                 340                 345

 Thr Phe Met Leu Leu Asp Gln Asn Asn Arg Glu His Ala Ile Asp
                 350                 355                 360

 Ala Phe Arg Pro Asp Leu Ser Ser Ala Ser Phe Gln Arg Pro Gln
                 365                 370                 375

 Ser Glu Thr Asn Val Ala Ser Gly Cys Pro Leu Phe Phe Pro Leu
                 380                 385                 390

 Ser Lys Leu Gln Ser Pro Lys His Ala Tyr Val Lys Asp Asp Thr
                 395                 400                 405

 Met Phe Leu Lys Cys Ile Val Glu Thr Ser Thr
                 410                 415

<210> 5689
<211> 865
<212> DNA
<213> Homo sapien

<400> 5689
 gaattccgga gttccgggcg cgcgcgacgt cagtttgagt tctgtgttct 50

 ccccgcccgt gtcccgcccg acccgcgccc gcgatgctgg cgctgcgctg 100

 cggctcccgc tggctcggcc tgctctccgt cccgcgctcc gtgccgctgc 150

 gcctccccgc ggcccgcgcc tgcagcaagg gctccggcga cccgtcctct 200

 tcctcctcct ccgggaaccc gctcgtgtac ctggacgtgg acgccaacgg 250

 gaagccgctc ggccgcgtgg tgctggagct gaaggcagat gtcgtcccaa 300

 agacagctga gaacttcaga gccctgtgca ctggtgagaa gggcttcggc 350

 tacaaaggct ccaccttcca cagggtgatc ccttccttca tgtgccaggc 400

 gggcgacttc accaaccaca atggcacagg cgggaagtcc atctacggaa 450

 gccgctttcc tgacgagaac tttacactga agcacgtggg gccaggtgtc 500

 ctgtccatgg ctaatgctgg tcctaacacc aacggctccc agttcttcat 550

 ctgcaccata aagacagact ggttggatgg caagcatgtt gtgttcggtc 600

 acgtcaaaga gggcatggac gtcgtgaaga aaatagaatc tttcggctct 650

 aagagtggga ggacatccaa gaagattgtc atcacagact gtggccagtt 700

 gagctaatct gtggccaggg tgctggcatg gtggcagctg caaatgtcca 750

 tgcacccagg tggccgcgtt gggctgtcag ccaaggtgcc tgaaacgata 800

 cgtgtgccca ctccactgtc acagtgtgcc tgaggaaggc tgctagggat 850

 gttagacgga attcc 865

<210> 5690
<211> 207
<212> PRT
<213> Homo sapien

<400> 5690
 Met Leu Ala Leu Arg Cys Gly Ser Arg Trp Leu Gly Leu Leu Ser
   1               5                  10                  15

 Val Pro Arg Ser Val Pro Leu Arg Leu Pro Ala Ala Arg Ala Cys
                  20                  25                  30

 Ser Lys Gly Ser Gly Asp Pro Ser Ser Ser Ser Ser Ser Gly Asn
                  35                  40                  45

 Pro Leu Val Tyr Leu Asp Val Asp Ala Asn Gly Lys Pro Leu Gly
                  50                  55                  60

 Arg Val Val Leu Glu Leu Lys Ala Asp Val Val Pro Lys Thr Ala
                  65                  70                  75

 Glu Asn Phe Arg Ala Leu Cys Thr Gly Glu Lys Gly Phe Gly Tyr
                  80                  85                  90

 Lys Gly Ser Thr Phe His Arg Val Ile Pro Ser Phe Met Cys Gln
                  95                 100                 105

 Ala Gly Asp Phe Thr Asn His Asn Gly Thr Gly Gly Lys Ser Ile
                 110                 115                 120

 Tyr Gly Ser Arg Phe Pro Asp Glu Asn Phe Thr Leu Lys His Val
                 125                 130                 135

 Gly Pro Gly Val Leu Ser Met Ala Asn Ala Gly Pro Asn Thr Asn
                 140                 145                 150

 Gly Ser Gln Phe Phe Ile Cys Thr Ile Lys Thr Asp Trp Leu Asp
                 155                 160                 165

 Gly Lys His Val Val Phe Gly His Val Lys Glu Gly Met Asp Val
                 170                 175                 180

 Val Lys Lys Ile Glu Ser Phe Gly Ser Lys Ser Gly Arg Thr Ser
                 185                 190                 195

 Lys Lys Ile Val Ile Thr Asp Cys Gly Gln Leu Ser
                 200                 205

<210> 5691
<211> 5826
<212> DNA
<213> Homo sapien

<400> 5691
 ccaggagagc ggcgtggacg cgtgcgggcc tagaggccca cgtgatccgc 50

 agggcggccg aggcaggaag ctgtgagtgc gcggttgcgg ggtcgcattg 100

 tggctacggc tttgcgtccc cggcgggcag ccccaggctg gtccccgcct 150

 ccgctctccc caccggcggg gaaagcagct ggtgtgggag gaaaggctcc 200

 atcccccgcc ccctctctcc cgctgttggc tggcaggatc ttttggcagt 250

 cctgtggcct cgctccccgc ccggatcctc ctgaccctga gattcgcggg 300

 tctcacgtcc cgtgcacgcc ttgcttcggc ctcagttaag cctttgtgga 350

 ctccaggtcc ctggtgagat tagaaacgtt tgcaaacatg tcccggatcg 400

 aaaagatgag cattctgggc gtgcggagtt ttggaataga ggacaaagat 450

 aagcaaatta tcactttctt cagccccctt acaattttgg ttggacccaa 500

 tggggcggga aagacgacca tcattgaatg tctaaaatat atttgtactg 550

 gagatttccc tcctggaacc aaaggaaata catttgtaca cgatcccaag 600

 gttgctcaag aaacagatgt gagagcccag attcgtctgc aatttcgtga 650

 tgtcaatgga gaacttatag ctgtgcaaag atctatggca tggtgaaaag 700

 gtcagtctga gctctaagtg tgcagaaatt gaccgagaaa tgatcagttc 750

 tcttggggtt tccaaggctg tgctaaataa tgtcattttc tgtcatcaag 800

 aagattctaa ttggccttta agtgaaggaa aggctttgaa gcaaaagttt 850

 gatgagattt tttcagcaac aagatacatt aaagccttag aaacacttcg 900

 gcaggtacgt cagacacaag gtcagaaagt aaaagaatat caaatggaac 950

 taaaatatct gaagcaatat aaggaaaaag cttgtgagat tcgtgatcag 1000

 attacaagta aggaagccca gttaacatct tcaaaggaaa ttgtcaaatc 1050

 ctatgagaat gaacttgatc cattgaagaa tcgtctaaaa gaaattgaac 1100

 ataatctctc taaaataatg aaacttgaca atgaaattaa agccttggat 1150

 agccgaaaga agcaaatgga gaaagataat agtgaactgg aagagaaaat 1200

 ggaaaaggtt tttcaaggga ctgatgagca actaaatgac ttatatcaca 1250

 atcaccagag aacagtaagg gagaaagaaa ggaaattggt agactgtcat 1300

 cgtgaactgg aaaaactaaa taaagaatct aggcttctca atcaggaaaa 1350

 atcagaactg cttgttgaac agggtcgtct acagctgcaa gcagatcgcc 1400

 atcaagaaca tatccgagct agagattcat taattcagtc tttggcaaca 1450

 cagctagaat tggatggctt tgagcgtgga ccattcagtg aaagacagat 1500

 taaaaatttt cacaaacttg tgagagagag acaagaaggg gaagcaaaaa 1550

 ctgccaacca actgatgaat gactttgcag aaaaagagac tctgaaacaa 1600

 aaacagatag atgagataag agataagaaa actggactgg gaagaataat 1650

 tgagttaaaa tcagaaatcc taagtaagaa gcagaatgag ctgaaaaatg 1700

 tgaagtatga attacagcag ttggaaggat cttcagacag gattcttgaa 1750

 ctggaccagg agctcataaa agctgaacgt gagttaagca aggctgagaa 1800

 aaacagcaat gtagaaacct taaaaatgga agtaataagt ctccaaaatg 1850

 aaaaagcaga cttagacagg accctgcgta aacttgacca ggagatggag 1900

 cagttaaacc atcatacaac aacacgtacc caaatggaga tgctgaccaa 1950

 agacaaagct gacaaagatg aacaaatcag aaaaataaaa tctaggcaca 2000

 gtgatgaatt aacctcactg ttgggatatt ttcccaacaa aaaacagctt 2050

 gaagactggc tacatagtaa atcaaaagaa attaatcaga ccagggacag 2100

 acttgccaaa ttgaacaagg aactagcttc atctgagcag aataaaaatc 2150

 atataaataa tgaactaaaa agaaaggaag agcagttgtc cagttacgaa 2200

 gacaagctgt ttgatgtttg tggtagccag gattttgaaa gtgatttaga 2250

 caggcttaaa gaggaaattg aaaaatcatc aaaacagcga gccatgctgg 2300

 ctggagccac agcagtttac tcccagttca ttactcagct aacagacgaa 2350

 aaccagtcat gttgccccgt ttgtcagaga gtttttcaga cagaggctga 2400

 gttacaagaa gtcatcagtg atttgcagtc taaactgcga cttgctccag 2450

 ataaactcaa gtcaacagaa tcagagctaa aaaaaaagga aaagcggcgt 2500

 gatgaaatgc tgggacttgt gcccatgagg caaagcataa ttgatttgaa 2550

 ggagaaggaa ataccagaat taagaaacaa actgcagaat gtcaatagag 2600

 acatacagcg cctaaagaac gacatagaag aacaagaaac actcttgggt 2650

 acaataatgc ctgaagaaga aagtgccaaa gtatgcctga cagatgttac 2700

 aattatggag aggttccaga tggaacttaa agatgttgaa agaaaaattg 2750

 cacaacaagc agctaagcta caaggaatag acttagatcg aactgtccaa 2800

 caagtcaacc aggagaaaca agagaaacag cacaagttag acacagtttc 2850

 tagtaagatt gaattgaatc gtaagcttat acaggaccag caggaacaga 2900

 ttcaacatct aaaaagtaca acaaatgagc taaaatctga gaaacttcag 2950

 atatccacta atttgcaacg tcgtcagcaa ctggaggagc agactgtgga 3000

 attatccact gaagttcagt ctttgtacag agagataaag gatgctaaag 3050

 agcaggtaag ccctttggaa acaacattgg aaaagttcca gcaagaaaaa 3100

 gaagaattaa tcaacaaaaa aaatacaagc aacaaaatag cacaggataa 3150

 actgaatgat attaaagaga aggttaaaaa tattcatggc tatatgaaag 3200

 acattgagaa ttatattcaa gatgggaaag acgactataa gaagcaaaaa 3250

 gaaactgaac ttaataaagt aatagctcaa ctaagtgaat gcgagaaaca 3300

 caaagaaaag ataaatgaag atatgagact catgagacaa gatattgata 3350

 cacagaagat acaagaaagg tggctacaag ataaccttac tttaagaaaa 3400

 agaaatgagg aactaaaaga agttgaagaa gaaagaaaac aacatttgaa 3450

 ggaaatgggt caaatgcagg ttttgcaaat gaaaagtgaa catcagaagt 3500

 tggaagagaa catagacaat ataaaaagaa atcataattt ggcattaggg 3550

 cgacagaaag gttatgaaga agaaattatt cattttaaga aagaacttcg 3600

 agaaccacaa tttcgggatg ctgaggaaaa gtatagagaa atgatgattg 3650

 ttatgaggac aacagaactt gtgaacaagg atctggatat ttattataag 3700

 actcttgacc aagcaataat gaaatttcac agtatgaaaa tggaagaaat 3750

 caataaaatt atacgtgacc tgtggcgaag tacctatcgt ggacaagata 3800

 ttgaatacat agaaatacgg tctgatgccg atgaaaatgt atcagcttct 3850

 gataaaaggc ggaattataa ctaccgagtg gtgatgctga agggagacac 3900

 agccttggat atgcgaggac gatgcagtgc tggacaaaag gtattagcct 3950

 cactcatcat tcgcctggcc ctggctgaaa cgttctgcct caactgtggc 4000

 atcattgcct tggatgagcc aacaacaaat cttgaccgag aaaacattga 4050

 atctcttgca catgctctgg ttgagataat aaaaagtcgc tcacagcagc 4100

 gtaacttcca gcttctggta atcactcatg atgaagattt tgtggagctt 4150

 ttaggacgtt ctgaatatgt ggagaaattc tacaggatta aaaagaacat 4200

 cgatcagtgc tcagagattg tgaaatgcag tgttagctcc ctgggattca 4250

 atgttcatta aaaatatcca agatttaaat gccatagaaa tgtaggtcct 4300

 cagaaagtgt ataataagaa acttatttct catatcaact tagtcaataa 4350

 gaaaatatat tctttcaaag gaacattgtg tctaggattt tggatgttga 4400

 gaggttctaa aatcatgaaa cttgtttcac tgaaaattgg acagattgcc 4450

 tgtttctgat ttgctgctct tcatcccatt ccaggcagcc tctgtcaggc 4500

 cttcagggtt cagcagtaca gccgagactc gactctgtgc ctccctcccc 4550

 agtgcaaatg catgcttctt ctcaaagcac tgttgagaag gagataatta 4600

 ctgccttgaa aatttatggt tttggtattt ttttaaatca tagttaaatg 4650

 ttacctctga atttacttcc ttgcatgtgg tttgaaaaac tgagtattaa 4700

 tatctgagga tgaccagaaa tggtgagatg tatgtttggc tctgctttta 4750

 actttataaa tccagtgacc tctctctctg ggacttggtt tccccaacta 4800

 aaatttgaag tagttgaatg gggtctcaaa gtttgacagg aaccttaagt 4850

 aatcatctaa gtcagtaccc accaccttct tctcctacat atcccttcca 4900

 gatggtcatc cagactcaga gctctctcta cagagaggaa attctccact 4950

 gtgcacaccc acctttggaa agctctgacc acttgaggcc tgatctgccc 5000

 atcgtgaaga agcctgtaac actcctctgc gtctatcctg tgtagcatac 5050

 tggcttcacc atcaatcctg attcctctct aagtgggcat tgccatgtgg 5100

 aaggcaagcc aggctcactc acagagtcaa ggcctgctcc ctgtagggtc 5150

 caaccagacc tggaagaaca ggcctctcca tttgctcttc agatgccact 5200

 tctaagaaaa gcctaatcac agtttttcct ggaattgcca gctgacatct 5250

 tgaatccttc cattccacac agaatgcaac caagtcacac gcttttgaat 5300

 tatgctttgt agagttttgt cattcagagt cagccaggac cataccgggt 5350

 cttgattcag tcacatggca tggttttgtg ccatctgtag ctataatgag 5400

 catgtttgcc tagacagctt ttctcaactg ggtccagaag agaattaagc 5450

 cctaaggtcc taaggcatct atctgtgcta ggttaaatgg ttggccccca 5500

 aagatagaca ggtcctgatt tctagaaccc gtgactgtta ctttatacag 5550

 caaaggaaac tttgcagatg tgattaaagc taaggacctt aagacagagt 5600

 atcctggggg tggtggtggg gtgggggggg gtcctaaatg taatcacgag 5650

 taagattaag agcaaatcaa ttctagtcat atattaaaca tccacaataa 5700

 ccaagatatt tttatcccaa gaatgcaaga tttcagaaaa tgaaaaatct 5750

 gttgataaat ccatcactat aataaaaccg aaggtgaaaa aaattctgaa 5800

 aaaaaaaaaa aaaaaaaaaa aaaaaa 5826

<210> 5692
<211> 1173
<212> PRT
<213> Homo sapien

<400> 5692
 Met Ile Ser Ser Leu Gly Val Ser Lys Ala Val Leu Asn Asn Val
   1               5                  10                  15

 Ile Phe Cys His Gln Glu Asp Ser Asn Trp Pro Leu Ser Glu Gly
                  20                  25                  30

 Lys Ala Leu Lys Gln Lys Phe Asp Glu Ile Phe Ser Ala Thr Arg
                  35                  40                  45

 Tyr Ile Lys Ala Leu Glu Thr Leu Arg Gln Val Arg Gln Thr Gln
                  50                  55                  60

 Gly Gln Lys Val Lys Glu Tyr Gln Met Glu Leu Lys Tyr Leu Lys
                  65                  70                  75

 Gln Tyr Lys Glu Lys Ala Cys Glu Ile Arg Asp Gln Ile Thr Ser
                  80                  85                  90

 Lys Glu Ala Gln Leu Thr Ser Ser Lys Glu Ile Val Lys Ser Tyr
                  95                 100                 105

 Glu Asn Glu Leu Asp Pro Leu Lys Asn Arg Leu Lys Glu Ile Glu
                 110                 115                 120

 His Asn Leu Ser Lys Ile Met Lys Leu Asp Asn Glu Ile Lys Ala
                 125                 130                 135

 Leu Asp Ser Arg Lys Lys Gln Met Glu Lys Asp Asn Ser Glu Leu
                 140                 145                 150

 Glu Glu Lys Met Glu Lys Val Phe Gln Gly Thr Asp Glu Gln Leu
                 155                 160                 165

 Asn Asp Leu Tyr His Asn His Gln Arg Thr Val Arg Glu Lys Glu
                 170                 175                 180

 Arg Lys Leu Val Asp Cys His Arg Glu Leu Glu Lys Leu Asn Lys
                 185                 190                 195

 Glu Ser Arg Leu Leu Asn Gln Glu Lys Ser Glu Leu Leu Val Glu
                 200                 205                 210

 Gln Gly Arg Leu Gln Leu Gln Ala Asp Arg His Gln Glu His Ile
                 215                 220                 225

 Arg Ala Arg Asp Ser Leu Ile Gln Ser Leu Ala Thr Gln Leu Glu
                 230                 235                 240

 Leu Asp Gly Phe Glu Arg Gly Pro Phe Ser Glu Arg Gln Ile Lys
                 245                 250                 255

 Asn Phe His Lys Leu Val Arg Glu Arg Gln Glu Gly Glu Ala Lys
                 260                 265                 270

 Thr Ala Asn Gln Leu Met Asn Asp Phe Ala Glu Lys Glu Thr Leu
                 275                 280                 285

 Lys Gln Lys Gln Ile Asp Glu Ile Arg Asp Lys Lys Thr Gly Leu
                 290                 295                 300

 Gly Arg Ile Ile Glu Leu Lys Ser Glu Ile Leu Ser Lys Lys Gln
                 305                 310                 315

 Asn Glu Leu Lys Asn Val Lys Tyr Glu Leu Gln Gln Leu Glu Gly
                 320                 325                 330

 Ser Ser Asp Arg Ile Leu Glu Leu Asp Gln Glu Leu Ile Lys Ala
                 335                 340                 345

 Glu Arg Glu Leu Ser Lys Ala Glu Lys Asn Ser Asn Val Glu Thr
                 350                 355                 360

 Leu Lys Met Glu Val Ile Ser Leu Gln Asn Glu Lys Ala Asp Leu
                 365                 370                 375

 Asp Arg Thr Leu Arg Lys Leu Asp Gln Glu Met Glu Gln Leu Asn
                 380                 385                 390

 His His Thr Thr Thr Arg Thr Gln Met Glu Met Leu Thr Lys Asp
                 395                 400                 405

 Lys Ala Asp Lys Asp Glu Gln Ile Arg Lys Ile Lys Ser Arg His
                 410                 415                 420

 Ser Asp Glu Leu Thr Ser Leu Leu Gly Tyr Phe Pro Asn Lys Lys
                 425                 430                 435

 Gln Leu Glu Asp Trp Leu His Ser Lys Ser Lys Glu Ile Asn Gln
                 440                 445                 450

 Thr Arg Asp Arg Leu Ala Lys Leu Asn Lys Glu Leu Ala Ser Ser
                 455                 460                 465

 Glu Gln Asn Lys Asn His Ile Asn Asn Glu Leu Lys Arg Lys Glu
                 470                 475                 480

 Glu Gln Leu Ser Ser Tyr Glu Asp Lys Leu Phe Asp Val Cys Gly
                 485                 490                 495

 Ser Gln Asp Phe Glu Ser Asp Leu Asp Arg Leu Lys Glu Glu Ile
                 500                 505                 510

 Glu Lys Ser Ser Lys Gln Arg Ala Met Leu Ala Gly Ala Thr Ala
                 515                 520                 525

 Val Tyr Ser Gln Phe Ile Thr Gln Leu Thr Asp Glu Asn Gln Ser
                 530                 535                 540

 Cys Cys Pro Val Cys Gln Arg Val Phe Gln Thr Glu Ala Glu Leu
                 545                 550                 555

 Gln Glu Val Ile Ser Asp Leu Gln Ser Lys Leu Arg Leu Ala Pro
                 560                 565                 570

 Asp Lys Leu Lys Ser Thr Glu Ser Glu Leu Lys Lys Lys Glu Lys
                 575                 580                 585

 Arg Arg Asp Glu Met Leu Gly Leu Val Pro Met Arg Gln Ser Ile
                 590                 595                 600

 Ile Asp Leu Lys Glu Lys Glu Ile Pro Glu Leu Arg Asn Lys Leu
                 605                 610                 615

 Gln Asn Val Asn Arg Asp Ile Gln Arg Leu Lys Asn Asp Ile Glu
                 620                 625                 630

 Glu Gln Glu Thr Leu Leu Gly Thr Ile Met Pro Glu Glu Glu Ser
                 635                 640                 645

 Ala Lys Val Cys Leu Thr Asp Val Thr Ile Met Glu Arg Phe Gln
                 650                 655                 660

 Met Glu Leu Lys Asp Val Glu Arg Lys Ile Ala Gln Gln Ala Ala
                 665                 670                 675

 Lys Leu Gln Gly Ile Asp Leu Asp Arg Thr Val Gln Gln Val Asn
                 680                 685                 690

 Gln Glu Lys Gln Glu Lys Gln His Lys Leu Asp Thr Val Ser Ser
                 695                 700                 705

 Lys Ile Glu Leu Asn Arg Lys Leu Ile Gln Asp Gln Gln Glu Gln
                 710                 715                 720

 Ile Gln His Leu Lys Ser Thr Thr Asn Glu Leu Lys Ser Glu Lys
                 725                 730                 735

 Leu Gln Ile Ser Thr Asn Leu Gln Arg Arg Gln Gln Leu Glu Glu
                 740                 745                 750

 Gln Thr Val Glu Leu Ser Thr Glu Val Gln Ser Leu Tyr Arg Glu
                 755                 760                 765

 Ile Lys Asp Ala Lys Glu Gln Val Ser Pro Leu Glu Thr Thr Leu
                 770                 775                 780

 Glu Lys Phe Gln Gln Glu Lys Glu Glu Leu Ile Asn Lys Lys Asn
                 785                 790                 795

 Thr Ser Asn Lys Ile Ala Gln Asp Lys Leu Asn Asp Ile Lys Glu
                 800                 805                 810

 Lys Val Lys Asn Ile His Gly Tyr Met Lys Asp Ile Glu Asn Tyr
                 815                 820                 825

 Ile Gln Asp Gly Lys Asp Asp Tyr Lys Lys Gln Lys Glu Thr Glu
                 830                 835                 840

 Leu Asn Lys Val Ile Ala Gln Leu Ser Glu Cys Glu Lys His Lys
                 845                 850                 855

 Glu Lys Ile Asn Glu Asp Met Arg Leu Met Arg Gln Asp Ile Asp
                 860                 865                 870

 Thr Gln Lys Ile Gln Glu Arg Trp Leu Gln Asp Asn Leu Thr Leu
                 875                 880                 885

 Arg Lys Arg Asn Glu Glu Leu Lys Glu Val Glu Glu Glu Arg Lys
                 890                 895                 900

 Gln His Leu Lys Glu Met Gly Gln Met Gln Val Leu Gln Met Lys
                 905                 910                 915

 Ser Glu His Gln Lys Leu Glu Glu Asn Ile Asp Asn Ile Lys Arg
                 920                 925                 930

 Asn His Asn Leu Ala Leu Gly Arg Gln Lys Gly Tyr Glu Glu Glu
                 935                 940                 945

 Ile Ile His Phe Lys Lys Glu Leu Arg Glu Pro Gln Phe Arg Asp
                 950                 955                 960

 Ala Glu Glu Lys Tyr Arg Glu Met Met Ile Val Met Arg Thr Thr
                 965                 970                 975

 Glu Leu Val Asn Lys Asp Leu Asp Ile Tyr Tyr Lys Thr Leu Asp
                 980                 985                 990

 Gln Ala Ile Met Lys Phe His Ser Met Lys Met Glu Glu Ile Asn
                 995                1000                1005

 Lys Ile Ile Arg Asp Leu Trp Arg Ser Thr Tyr Arg Gly Gln Asp
                1010                1015                1020

 Ile Glu Tyr Ile Glu Ile Arg Ser Asp Ala Asp Glu Asn Val Ser
                1025                1030                1035

 Ala Ser Asp Lys Arg Arg Asn Tyr Asn Tyr Arg Val Val Met Leu
                1040                1045                1050

 Lys Gly Asp Thr Ala Leu Asp Met Arg Gly Arg Cys Ser Ala Gly
                1055                1060                1065

 Gln Lys Val Leu Ala Ser Leu Ile Ile Arg Leu Ala Leu Ala Glu
                1070                1075                1080

 Thr Phe Cys Leu Asn Cys Gly Ile Ile Ala Leu Asp Glu Pro Thr
                1085                1090                1095

 Thr Asn Leu Asp Arg Glu Asn Ile Glu Ser Leu Ala His Ala Leu
                1100                1105                1110

 Val Glu Ile Ile Lys Ser Arg Ser Gln Gln Arg Asn Phe Gln Leu
                1115                1120                1125

 Leu Val Ile Thr His Asp Glu Asp Phe Val Glu Leu Leu Gly Arg
                1130                1135                1140

 Ser Glu Tyr Val Glu Lys Phe Tyr Arg Ile Lys Lys Asn Ile Asp
                1145                1150                1155

 Gln Cys Ser Glu Ile Val Lys Cys Ser Val Ser Ser Leu Gly Phe
                1160                1165                1170

 Asn Val His


<210> 5693
<211> 2376
<212> DNA
<213> Homo sapien

<400> 5693
 cgcgcggccc ctgtcctccg gcccgagatg aatcctgcgg cagaagccga 50

 gttcaacatc ctcctggcca ccgactccta caaggttact cactataaac 100

 aatatccacc caacacaagc aaagtttatt cctactttga atgccgtgaa 150

 aagaagacag aaaactccaa attaaggaag gtgaaatatg aggaaacagt 200

 attttatggg ttgcagtaca ttcttaataa gtacttaaaa ggtaaagtag 250

 taaccaaaga gaaaatccag gaagccaaag atgtctacaa agaacatttc 300

 caagatgatg tctttaatga aaagggatgg aactacattc ttgagaagta 350

 tgatgggcat cttccaatag aaataaaagc tgttcctgag ggctttgtca 400

 ttcccagagg aaatgttctc ttcacggtgg aaaacacaga tccagagtgt 450

 tactggctta caaattggat tgagactatt cttgttcagt cctggtatcc 500

 aatcacagtg gccacaaatt ctagagagca gaagaaaata ttggccaaat 550

 atttgttaga aacttctggt aacttagatg gtctggaata caagttacat 600

 gattttggct acagaggagt ctcttcccaa gagactgctg gcataggagc 650

 atctgctcac ttggttaact tcaaaggaac agatacagta gcaggacttg 700

 ctctaattaa aaaatattat ggaacgaaag atcctgttcc aggctattct 750

 gttccagcag cagaacacag taccataaca gcttggggga aagaccatga 800

 aaaagatgct tttgaacata ttgtaacaca gttttcatca gtgcctgtat 850

 ctgtggtcag cgatagctat gacatttata atgcgtgtga gaaaatatgg 900

 ggtgaagatc taagacattt aatagtatcg agaagtacac aggcaccact 950

 aataatcaga cctgattctg gaaaccctct tgacactgtg ttaaaggttt 1000

 tggagatttt aggtaagaag tttcctgtta ctgagaactc aaagggttac 1050

 aagttgctgc caccttatct tagagttatt caaggggatg gagtagatat 1100

 taatacctta caagagattg tagaaggcat gaaacaaaaa atgtggagta 1150

 ttgaaaatat tgccttcggt tctggtggag gtttgctaca gaagttgaca 1200

 agagatctct tgaattgttc cttcaagtgt agctatgttg taactaatgg 1250

 ccttgggatt aacgtcttca aggacccagt tgctgatccc aacaaaaggt 1300

 ccaaaaaggg ccgattatct ttacatagga cgccagcagg gaattttgtt 1350

 acactggagg aaggaaaagg agaccttgag gaatatggtc aggatcttct 1400

 ccatactgtc ttcaagaatg gcaaggtgac aaaaagctat tcatttgatg 1450

 aaataagaaa aaatgcacag ctgaatattg aactggaagc agcacatcat 1500

 taggctttat gactgggtgt gtgttgtgtg tatgtaatac ataatgttta 1550

 ttgtacagat gtgtggggtt tgtgttttat gatacattac agccaaatta 1600

 tttgttggtt tatggacata ctgccctttc attttttttc ttttccagtg 1650

 tttaggtgat ctcaaattag gaaatgcatt taaccatgta aaagatgagt 1700

 gctaaagtaa gctttttagg gccctttgcc aataggtagt cattcaatct 1750

 ggtattgatc ttttcacaaa taacagaact gagaaacttt tatatataac 1800

 tgatgatcac ataaaacaga tttgcataaa attaccatga ttgctttatg 1850

 tttatattta acttgtattt ttgtacaaac aagattgtgt aagatatatt 1900

 tgaagtttca gtgatttaac agtctttcca acttttcatg atttttatga 1950

 gcacagactt tcaagaaaat acttgaaaat aaattacatt gccttttgtc 2000

 cattaatcag caaataaaac atggccttaa caaagttgtt tgtgttattg 2050

 tacaatttga aaattatgtc gggacatacc ctatagaatt actaacctta 2100

 ctgccccttg tagaatatgt attaatcatt ctacattaaa gaaaataatg 2150

 gttcttactg gaatgtctag gcactgtaca gttattatat atcttggttg 2200

 ttgtattgta ccagtgaaat gccaaatttg aaaggcctgt actgcaattt 2250

 tatatgtcag agattgcctg tggctctaat atgcacctca agattttaag 2300

 gagataatgt ttttagagag aatttctgct tccactatag aatatataca 2350

 taaatgtaaa atacttacaa aagtgg 2376

<210> 5694
<211> 491
<212> PRT
<213> Homo sapien

<400> 5694
 Met Asn Pro Ala Ala Glu Ala Glu Phe Asn Ile Leu Leu Ala Thr
   1               5                  10                  15

 Asp Ser Tyr Lys Val Thr His Tyr Lys Gln Tyr Pro Pro Asn Thr
                  20                  25                  30

 Ser Lys Val Tyr Ser Tyr Phe Glu Cys Arg Glu Lys Lys Thr Glu
                  35                  40                  45

 Asn Ser Lys Leu Arg Lys Val Lys Tyr Glu Glu Thr Val Phe Tyr
                  50                  55                  60

 Gly Leu Gln Tyr Ile Leu Asn Lys Tyr Leu Lys Gly Lys Val Val
                  65                  70                  75

 Thr Lys Glu Lys Ile Gln Glu Ala Lys Asp Val Tyr Lys Glu His
                  80                  85                  90

 Phe Gln Asp Asp Val Phe Asn Glu Lys Gly Trp Asn Tyr Ile Leu
                  95                 100                 105

 Glu Lys Tyr Asp Gly His Leu Pro Ile Glu Ile Lys Ala Val Pro
                 110                 115                 120

 Glu Gly Phe Val Ile Pro Arg Gly Asn Val Leu Phe Thr Val Glu
                 125                 130                 135

 Asn Thr Asp Pro Glu Cys Tyr Trp Leu Thr Asn Trp Ile Glu Thr
                 140                 145                 150

 Ile Leu Val Gln Ser Trp Tyr Pro Ile Thr Val Ala Thr Asn Ser
                 155                 160                 165

 Arg Glu Gln Lys Lys Ile Leu Ala Lys Tyr Leu Leu Glu Thr Ser
                 170                 175                 180

 Gly Asn Leu Asp Gly Leu Glu Tyr Lys Leu His Asp Phe Gly Tyr
                 185                 190                 195

 Arg Gly Val Ser Ser Gln Glu Thr Ala Gly Ile Gly Ala Ser Ala
                 200                 205                 210

 His Leu Val Asn Phe Lys Gly Thr Asp Thr Val Ala Gly Leu Ala
                 215                 220                 225

 Leu Ile Lys Lys Tyr Tyr Gly Thr Lys Asp Pro Val Pro Gly Tyr
                 230                 235                 240

 Ser Val Pro Ala Ala Glu His Ser Thr Ile Thr Ala Trp Gly Lys
                 245                 250                 255

 Asp His Glu Lys Asp Ala Phe Glu His Ile Val Thr Gln Phe Ser
                 260                 265                 270

 Ser Val Pro Val Ser Val Val Ser Asp Ser Tyr Asp Ile Tyr Asn
                 275                 280                 285

 Ala Cys Glu Lys Ile Trp Gly Glu Asp Leu Arg His Leu Ile Val
                 290                 295                 300

 Ser Arg Ser Thr Gln Ala Pro Leu Ile Ile Arg Pro Asp Ser Gly
                 305                 310                 315

 Asn Pro Leu Asp Thr Val Leu Lys Val Leu Glu Ile Leu Gly Lys
                 320                 325                 330

 Lys Phe Pro Val Thr Glu Asn Ser Lys Gly Tyr Lys Leu Leu Pro
                 335                 340                 345

 Pro Tyr Leu Arg Val Ile Gln Gly Asp Gly Val Asp Ile Asn Thr
                 350                 355                 360

 Leu Gln Glu Ile Val Glu Gly Met Lys Gln Lys Met Trp Ser Ile
                 365                 370                 375

 Glu Asn Ile Ala Phe Gly Ser Gly Gly Gly Leu Leu Gln Lys Leu
                 380                 385                 390

 Thr Arg Asp Leu Leu Asn Cys Ser Phe Lys Cys Ser Tyr Val Val
                 395                 400                 405

 Thr Asn Gly Leu Gly Ile Asn Val Phe Lys Asp Pro Val Ala Asp
                 410                 415                 420

 Pro Asn Lys Arg Ser Lys Lys Gly Arg Leu Ser Leu His Arg Thr
                 425                 430                 435

 Pro Ala Gly Asn Phe Val Thr Leu Glu Glu Gly Lys Gly Asp Leu
                 440                 445                 450

 Glu Glu Tyr Gly Gln Asp Leu Leu His Thr Val Phe Lys Asn Gly
                 455                 460                 465

 Lys Val Thr Lys Ser Tyr Ser Phe Asp Glu Ile Arg Lys Asn Ala
                 470                 475                 480

 Gln Leu Asn Ile Glu Leu Glu Ala Ala His His
                 485                 490

<210> 5695
<211> 1118
<212> DNA
<213> Homo sapien

<400> 5695
 ctgatgaaag tgcttccaaa ctgaaaattg gacgtgcctt tacgatggta 50

 agcgttaaca gctcccactg cttctataat gactccttta agtacacttt 100

 gtatgggtgc atgttcagca tggtgtttgt gcttgggtta gtatccaatt 150

 gtgttgccat atacattttc atctgcgtcc tcaaagtccg aaatgaaact 200

 acaacttaca tgattaactt ggcaatgtca gacttgcttt ttgtttttac 250

 tttacccttc aggatttttt acttcacaac acggaattgg ccatttggag 300

 atttactttg taagatttct gtgatgctgt tttataccaa catgtacgga 350

 agcattctgt tcttaacctg tattagtgta gatcgatttc tggcaattgt 400

 ctacccattt aagtcaaaga ctctaagaac caaaagaaat gcaaagattg 450

 tttgcactgg cgtgtggtta actgtgatcg gaggaagtgc acccgccgtt 500

 tttgttcagt ctacccactc tcagggtaac aatgcctcag aagcctgctt 550

 tgaaaatttt ccagaagcca catggaaaac atatctctca aggattgtaa 600

 ttttcatcga aatagtggga ttttttattc ctctaatttt aaatgtaact 650

 tgttctagta tggtgctaaa aactttaacc aaaccagtta cattaagtag 700

 aagcaaaata aacaaaacta aggttttaaa aatgattttt gtacatttga 750

 tcatattctg tttctgtttt gttccttaca atatcaatct tattttatat 800

 tctcttgtga gaacacaaac atttgttaat tgctcagtag tggcagcagt 850

 aaggacaatg tacccaatca ctctctgtat tgctgtttcc aactgttgtt 900

 ttgaccctat agtttactac tttacatcgg acacaattca gaattcaata 950

 aaaatgaaaa actggtctgt caggagaagt gacttcagat tctctgaagt 1000

 tcatggtgca gagaatttta ttcagcataa cctacagacc ttaaaaagta 1050

 agatatttga caatgaatct gctgcctgaa ataaaaccat taggactcac 1100

 tgggacagaa ctttcaag 1118

<210> 5696
<211> 344
<212> PRT
<213> Homo sapien

<400> 5696
 Met Val Ser Val Asn Ser Ser His Cys Phe Tyr Asn Asp Ser Phe
   1               5                  10                  15

 Lys Tyr Thr Leu Tyr Gly Cys Met Phe Ser Met Val Phe Val Leu
                  20                  25                  30

 Gly Leu Val Ser Asn Cys Val Ala Ile Tyr Ile Phe Ile Cys Val
                  35                  40                  45

 Leu Lys Val Arg Asn Glu Thr Thr Thr Tyr Met Ile Asn Leu Ala
                  50                  55                  60

 Met Ser Asp Leu Leu Phe Val Phe Thr Leu Pro Phe Arg Ile Phe
                  65                  70                  75

 Tyr Phe Thr Thr Arg Asn Trp Pro Phe Gly Asp Leu Leu Cys Lys
                  80                  85                  90

 Ile Ser Val Met Leu Phe Tyr Thr Asn Met Tyr Gly Ser Ile Leu
                  95                 100                 105

 Phe Leu Thr Cys Ile Ser Val Asp Arg Phe Leu Ala Ile Val Tyr
                 110                 115                 120

 Pro Phe Lys Ser Lys Thr Leu Arg Thr Lys Arg Asn Ala Lys Ile
                 125                 130                 135

 Val Cys Thr Gly Val Trp Leu Thr Val Ile Gly Gly Ser Ala Pro
                 140                 145                 150

 Ala Val Phe Val Gln Ser Thr His Ser Gln Gly Asn Asn Ala Ser
                 155                 160                 165

 Glu Ala Cys Phe Glu Asn Phe Pro Glu Ala Thr Trp Lys Thr Tyr
                 170                 175                 180

 Leu Ser Arg Ile Val Ile Phe Ile Glu Ile Val Gly Phe Phe Ile
                 185                 190                 195

 Pro Leu Ile Leu Asn Val Thr Cys Ser Ser Met Val Leu Lys Thr
                 200                 205                 210

 Leu Thr Lys Pro Val Thr Leu Ser Arg Ser Lys Ile Asn Lys Thr
                 215                 220                 225

 Lys Val Leu Lys Met Ile Phe Val His Leu Ile Ile Phe Cys Phe
                 230                 235                 240

 Cys Phe Val Pro Tyr Asn Ile Asn Leu Ile Leu Tyr Ser Leu Val
                 245                 250                 255

 Arg Thr Gln Thr Phe Val Asn Cys Ser Val Val Ala Ala Val Arg
                 260                 265                 270

 Thr Met Tyr Pro Ile Thr Leu Cys Ile Ala Val Ser Asn Cys Cys
                 275                 280                 285

 Phe Asp Pro Ile Val Tyr Tyr Phe Thr Ser Asp Thr Ile Gln Asn
                 290                 295                 300

 Ser Ile Lys Met Lys Asn Trp Ser Val Arg Arg Ser Asp Phe Arg
                 305                 310                 315

 Phe Ser Glu Val His Gly Ala Glu Asn Phe Ile Gln His Asn Leu
                 320                 325                 330

 Gln Thr Leu Lys Ser Lys Ile Phe Asp Asn Glu Ser Ala Ala
                 335                 340

<210> 5697
<211> 918
<212> DNA
<213> Homo sapien

<400> 5697
 cacgagctta gctgaagatg actgacagtg ttatttattc catgttagag 50

 ttgcctacgg caacccaagc ccagaatgac tatggaccac agcaaaaatc 100

 ttcctcttcc aggccttctt gttcttgcct tgtggcaata gctttggggc 150

 ttctgactgc agttcttctg agtgtgctgc tataccagtg gatcctgtgc 200

 cagggctcca actactccac ttgtgccagc tgtcctagct gcccagaccg 250

 ctggatgaaa tatggtaacc attgttatta tttctcagtg gaggaaaagg 300

 actggaattc tagtctggaa ttctgcctag ccagagactc acacctcctt 350

 gtgataacgg acaatcagga aatgagcctg ctccaagttt tcctcagtga 400

 ggccttttgc tggattggtc tgaggaacaa ttctggctgg aggtgggaag 450

 atggatcacc tctaaacttc tcaaggattt cttctaatag ctttgtgcag 500

 acatgcggtg ccatcaacaa aaatggtctt caagcctcaa gctgtgaagt 550

 tcctttacac tgggtgtgta agaaggtcag actttgatag atgaccactc 600

 tgtcctgacc ctcagatctg tcatgtatcc ctaaaaggag ggagctggcc 650

 actggctgtt gggaaagcca tgagtatata gttagcaaat actgaacttt 700

 ctcagatatg gcattagatg caagacaacc tcctagggat tgatgcctaa 750

 ctgatggatt ctctttgaga ctatttagat attatgtgag caatttaaag 800

 accagatcta agcaaatttt gaaatagatg tttgtttttt gtatttctca 850

 gtatggaaac taatgctgcc actctcatcc ccgtcccaac catactctgt 900

 caaaaatata cctttttc 918

<210> 5698
<211> 189
<212> PRT
<213> Homo sapien

<400> 5698
 Met Thr Asp Ser Val Ile Tyr Ser Met Leu Glu Leu Pro Thr Ala
   1               5                  10                  15

 Thr Gln Ala Gln Asn Asp Tyr Gly Pro Gln Gln Lys Ser Ser Ser
                  20                  25                  30

 Ser Arg Pro Ser Cys Ser Cys Leu Val Ala Ile Ala Leu Gly Leu
                  35                  40                  45

 Leu Thr Ala Val Leu Leu Ser Val Leu Leu Tyr Gln Trp Ile Leu
                  50                  55                  60

 Cys Gln Gly Ser Asn Tyr Ser Thr Cys Ala Ser Cys Pro Ser Cys
                  65                  70                  75

 Pro Asp Arg Trp Met Lys Tyr Gly Asn His Cys Tyr Tyr Phe Ser
                  80                  85                  90

 Val Glu Glu Lys Asp Trp Asn Ser Ser Leu Glu Phe Cys Leu Ala
                  95                 100                 105

 Arg Asp Ser His Leu Leu Val Ile Thr Asp Asn Gln Glu Met Ser
                 110                 115                 120

 Leu Leu Gln Val Phe Leu Ser Glu Ala Phe Cys Trp Ile Gly Leu
                 125                 130                 135

 Arg Asn Asn Ser Gly Trp Arg Trp Glu Asp Gly Ser Pro Leu Asn
                 140                 145                 150

 Phe Ser Arg Ile Ser Ser Asn Ser Phe Val Gln Thr Cys Gly Ala
                 155                 160                 165

 Ile Asn Lys Asn Gly Leu Gln Ala Ser Ser Cys Glu Val Pro Leu
                 170                 175                 180

 His Trp Val Cys Lys Lys Val Arg Leu
                 185

<210> 5699
<211> 3184
<212> DNA
<213> Homo sapien

<400> 5699
 ctctgctgtg ctgcctcaaa cgcggagggc tgcgtgcagt gggagcgggc 50

 tccaggagcc cgagcctcca gccgtcctca gagcaaggca gcaccgaggc 100

 ctggccacag caatatccat ctggaagctc ttcccttcac tcccaactct 150

 gaggttgcct aactctttat taaaaattca gaagggggaa tgccagcccc 200

 tagcatggac tgtgatgttt ccactctggt tgcctgtgtg gtggatgtcg 250

 aggtctttac caatcaggag gttaaggaaa aatttggggg actgtttcgg 300

 acttatgatg actgtgtgac gttccagcta tttaagagtt tcagacgtgt 350

 ccgtataaac ttcagcaatc ctaaatctgc agcccgagct aggatagagc 400

 ttcatgaaac ccaattcaga gggaaaaaat taaagctcta ctttgcacag 450

 gttcagactc cagagacaga tggagacaaa ctgcacttgg ctccacccca 500

 gcctgccaaa cagtttctca tctcgccccc ttcctcccca cctgttagct 550

 ggcagcccat caacgatgcc acgccagtcc tcaactatga cctcctctat 600

 gctgtggcca aactaggacc aggagagaag tatgagctcc atgcagggac 650

 tgagtccacc ccaagtgtcg tcgtgcacgt gtgcgacagt gacatagagg 700

 aagaagagga cccaaagact tccccaaagc caaaaatcat ccaaactcgg 750

 cgtcctggcc tgccaccctc cgtgtccaac tgagctgcct gctccttctc 800

 gataatagcc gtctcctctt tatcatgctt tttccccctg ttgtttgtca 850

 aaaaaaattg cctttaaatt cctgggtgtt tggttgtttg agattccttc 900

 cttgttatca agcctctcgg acaaaagggc taggaaaagg tgatatgtct 950

 cctgatcata tcatacccat taagtataac ccattattta gaaggttcta 1000

 gggaaaaaag tagtattttc ttattaaaca atcagcacag cctatatctt 1050

 tgttctctca tgttgatcca agccagagac atcggtaaca aatagcacct 1100

 gtgttgtttg tgaggtgttt cagtcccagt cctgatgtgt gtgcgttgtt 1150

 ctctcctggc cacttaaata ggaccatatg taaacttgac tttgactgca 1200

 tgagatatcc ctatctggtc tcactcagtc ctctgcatcc caacattccc 1250

 aggacatgca tgatcaccag catttatttt cattatttga ggatatctta 1300

 taactcacag attgtcagca tccagccatg tcctatctag attaggaaaa 1350

 tgatcagaat attccagctc aacaagtctg ggtatactca ctattgtgag 1400

 tcaatacacc atagctctgt tgaaattcct ggaggcaaaa ttgaccttgg 1450

 ccccaaagat attcctcaat agatttcaaa caccactccc ctgtagaact 1500

 ctcccagcct cgttggggag gcttgtccag ggtgatagag actgatttca 1550

 gacaaaccta tttattacaa aagtttcatg gtgtctgaat gattgttttc 1600

 tctctttgta tatttgtaca aatgtttcag ctgtgctttt aaaaaatctg 1650

 gatgtttttt atttagtgat tgttcgacaa ttagctgctt caaaacataa 1700

 tgtgcattgc ttatgaatgc cttcatatac taatacagat actctgataa 1750

 tattacactc taataaggat aatgctgaat tttgaaagga cacaaaacat 1800

 ctaatgccaa tatatacatg gttagccaac atctttgcta tcaagaccac 1850

 ttgttttaaa taaagatgca agtgtcagtt gtagattatt gggatgaagc 1900

 taaatcccca gaatgcagca gcagctgagc atgttaaaat ggggaaggat 1950

 gatagctaca tgtatgccgg tcctactcac gcgacacccg tgtgctcaaa 2000

 aaagttactt gtttttgtta cgtgtgattt tcctatttct ctagcccaaa 2050

 gtgcattaca gaagatacac ctatagaacc attaccttct gctatgtgtg 2100

 ccagggctca tctactcctg tacattaatg gattacttta gatgcaaatg 2150

 cagattacaa tggagtgggg aagtactttc attacccaag cctcagaaaa 2200

 acacacaaga acaataacac agcaaacaga ttgagggatt gttgtggttt 2250

 ttgactaagg tgtatgttag tttcatcaga aacttaaaac atagactgat 2300

 cactcagaaa ttaaagtccg ttttactgtg aatatagcaa tatagtactg 2350

 gacacagtac tggtgaaact gaggagagca ttgcttgtaa aatcctgagt 2400

 ttccataagg aaaatgaaaa ctccttttaa aaataaaatc tgaggagtgt 2450

 acaataagca tatgctttga ctttcctttg ctgtggaggt ttttggtttt 2500

 tcattgatga taaacgacta cagacttagt agtggagaaa tggtgtcctc 2550

 tagtggaaga aatagtagct ccgctattca gatgcagagc actgcagcat 2600

 ccagcctttc aaagctgact cttctcaatc atctgtgggt catttgactt 2650

 gattttttaa gctaccctga atttccagaa tgcaggttct aaagaaatct 2700

 agatgagaga aagtatttga aaatgatttt taaatgtttt ttaaaagaca 2750

 catctgacat ttttaacaac ttagtaaaag ttgaaatgac cattctgtgt 2800

 agtcataaaa gaaacacaat gaagtgtatg gcctctggag ttagtcttag 2850

 taaaacttat tgctctgtgt caatgttaac ctgtctcaga tcaagtaatt 2900

 ccttcactag gttgggtttg gggagggggg aaaagagggg cttttcctag 2950

 gagaacgata agaaatggaa agactccttg aagtgttgca agggaacctc 3000

 ctagcactgt gaaagtcaga atcgcctcag catttccatg acgcacatta 3050

 tgcaaatctc tttagcacta ttttaaggtt gaaaacttta acaatgaagg 3100

 ggaaggggaa gatttccacc aactgaatca tttgtgcacg tgtatagctc 3150

 aaagagctta gacttcaaat atatctggtg aatg 3184

<210> 5700
<211> 192
<212> PRT
<213> Homo sapien

<400> 5700
 Met Asp Cys Asp Val Ser Thr Leu Val Ala Cys Val Val Asp Val
   1               5                  10                  15

 Glu Val Phe Thr Asn Gln Glu Val Lys Glu Lys Phe Gly Gly Leu
                  20                  25                  30

 Phe Arg Thr Tyr Asp Asp Cys Val Thr Phe Gln Leu Phe Lys Ser
                  35                  40                  45

 Phe Arg Arg Val Arg Ile Asn Phe Ser Asn Pro Lys Ser Ala Ala
                  50                  55                  60

 Arg Ala Arg Ile Glu Leu His Glu Thr Gln Phe Arg Gly Lys Lys
                  65                  70                  75

 Leu Lys Leu Tyr Phe Ala Gln Val Gln Thr Pro Glu Thr Asp Gly
                  80                  85                  90

 Asp Lys Leu His Leu Ala Pro Pro Gln Pro Ala Lys Gln Phe Leu
                  95                 100                 105

 Ile Ser Pro Pro Ser Ser Pro Pro Val Ser Trp Gln Pro Ile Asn
                 110                 115                 120

 Asp Ala Thr Pro Val Leu Asn Tyr Asp Leu Leu Tyr Ala Val Ala
                 125                 130                 135

 Lys Leu Gly Pro Gly Glu Lys Tyr Glu Leu His Ala Gly Thr Glu
                 140                 145                 150

 Ser Thr Pro Ser Val Val Val His Val Cys Asp Ser Asp Ile Glu
                 155                 160                 165

 Glu Glu Glu Asp Pro Lys Thr Ser Pro Lys Pro Lys Ile Ile Gln
                 170                 175                 180

 Thr Arg Arg Pro Gly Leu Pro Pro Ser Val Ser Asn
                 185                 190

<210> 5701
<211> 2126
<212> DNA
<213> Homo sapien

<400> 5701
 gtaaggccgt tttcttttcc cattcgctca tctgccagga aaagggactt 50

 gccgttggcg cttcggcctc ttgttcattg agaaaaaaga ggaaatactc 100

 cgcgtgcgct tgtagaaggg gagtcgtctc cagctccgaa ccccggagtg 150

 ttcatcagcg gggaatctgg ctccgaattc tctttttttc tcccgccgat 200

 tgctcggaag ttggtctaaa gcagaggttg gaaagaaagg aaaaaagttt 250

 gcatcgagac tggatttatt tgcacatcgc agaaagaaga gaatccaagg 300

 gagaggggtt ggtgcaaagc cgcgatcacg gagttcagat gtgttctaag 350

 cctgctggag tgaccacact tccaagacct gatggaggcc agagctcaga 400

 gtggcaacgg gtcgcagccc ttgctgcaga cgccccgtga cggtggcaga 450

 cagcgtgggg agcccgaccc cagagacgcc ctcacccagc aggtacatgt 500

 cttgtctctg gatcagatca gagccatccg aaacaccaat gagtacacag 550

 aggggcctac tgtcgtccca agacctgggc tcaagcctgc tcctcgcccc 600

 tccactcagc acaaacacga gagactccac ggtctgcctg agcaccgcca 650

 gcctcctagg ctccagcact cgcaggtcca ttcttctgca cgagcccctc 700

 tgtccagatc cataagcacg gtcagctcag ggtcgcggag cagtacgagg 750

 acaagtacca gcagcagctc ctctgaacag agactgctag gatcatcctt 800

 ctcctccggg cctgttgctg atggcataat ccgggtgcaa cccaaatctg 850

 agctcaagcc aggtgagctt aagccactga gcaaggaaga tttgggcctg 900

 cacgcctaca ggtgtgagga ctgtggcaag tgcaaatgta aggagtgcac 950

 ctacccaagg cctctgccat cagactggat ctgcgacaag cagtgccttt 1000

 gctcggccca gaacgtgatt gactatggga cttgtgtatg ctgtgtgaaa 1050

 ggtctcttct atcactgttc taatgatgat gaggacaact gtgctgacaa 1100

 cccatgttct tgcagccagt ctcactgttg tacacgatgg tcagccatgg 1150

 gtgtcatgtc cctctttttg ccttgtttat ggtgttacct tccagccaag 1200

 ggttgcctta aattgtgcca ggggtgttat gaccgggtta acaggcctgg 1250

 ttgccgctgt aaaaactcaa acacagtttg ctgcaaagtt cccactgtcc 1300

 cccctaggaa ctttgaaaaa ccaacatagc atcattaatc aggaatatta 1350

 cagtaatgag gattttttct ttcttttttt aatacacata tgcaaccaac 1400

 taaacagtta taatcttggc actgttaata gaaaggtggg atagtctttg 1450

 ctgtttgcgg tgaaatgctt tttgtccatg tgccgtttta actgatatgc 1500

 ttgttagaac tcagctaatg gagctcaaag tatgagatac agaacttggt 1550

 gacccatgta ttgcataagc taaagcaaca cagacactcc taggcaaagt 1600

 ttttgtttgt gaatagtact tgcaaaactt gtaaattagc agatgacttt 1650

 tttccattgt tttctccaga gagaatgtgc tatatttttg tatatacaat 1700

 aatatttgca actgtgaaaa acaagttgtg ccatactaca tggcacagac 1750

 acaaaatatt atactaatat gttgtacatt cggaagaatg tgaatcaatc 1800

 agtatgtttt tagattgtat tttgccttac agaaagcctt tattgtaaga 1850

 ctctgatttc cctttggact tcatgtatat tgtacagtta cagtaaaatt 1900

 caacctttat tttctaattt tttcaacata ttgtttagtg taaagaatat 1950

 ttatttgaag ttttattatt ttataaaaaa gaatatttat tttaagaggc 2000

 atcttacaaa ttttgcccct tttatgagga tgtgatagtt gctgcaaatg 2050

 aggggttaca gatgcatatg tccaatataa aatagaaaat atattaacgt 2100

 ttgaaattaa aaaaaaaaaa aaaaaa 2126

<210> 5702
<211> 315
<212> PRT
<213> Homo sapien

<400> 5702
 Met Glu Ala Arg Ala Gln Ser Gly Asn Gly Ser Gln Pro Leu Leu
   1               5                  10                  15

 Gln Thr Pro Arg Asp Gly Gly Arg Gln Arg Gly Glu Pro Asp Pro
                  20                  25                  30

 Arg Asp Ala Leu Thr Gln Gln Val His Val Leu Ser Leu Asp Gln
                  35                  40                  45

 Ile Arg Ala Ile Arg Asn Thr Asn Glu Tyr Thr Glu Gly Pro Thr
                  50                  55                  60

 Val Val Pro Arg Pro Gly Leu Lys Pro Ala Pro Arg Pro Ser Thr
                  65                  70                  75

 Gln His Lys His Glu Arg Leu His Gly Leu Pro Glu His Arg Gln
                  80                  85                  90

 Pro Pro Arg Leu Gln His Ser Gln Val His Ser Ser Ala Arg Ala
                  95                 100                 105

 Pro Leu Ser Arg Ser Ile Ser Thr Val Ser Ser Gly Ser Arg Ser
                 110                 115                 120

 Ser Thr Arg Thr Ser Thr Ser Ser Ser Ser Ser Glu Gln Arg Leu
                 125                 130                 135

 Leu Gly Ser Ser Phe Ser Ser Gly Pro Val Ala Asp Gly Ile Ile
                 140                 145                 150

 Arg Val Gln Pro Lys Ser Glu Leu Lys Pro Gly Glu Leu Lys Pro
                 155                 160                 165

 Leu Ser Lys Glu Asp Leu Gly Leu His Ala Tyr Arg Cys Glu Asp
                 170                 175                 180

 Cys Gly Lys Cys Lys Cys Lys Glu Cys Thr Tyr Pro Arg Pro Leu
                 185                 190                 195

 Pro Ser Asp Trp Ile Cys Asp Lys Gln Cys Leu Cys Ser Ala Gln
                 200                 205                 210

 Asn Val Ile Asp Tyr Gly Thr Cys Val Cys Cys Val Lys Gly Leu
                 215                 220                 225

 Phe Tyr His Cys Ser Asn Asp Asp Glu Asp Asn Cys Ala Asp Asn
                 230                 235                 240

 Pro Cys Ser Cys Ser Gln Ser His Cys Cys Thr Arg Trp Ser Ala
                 245                 250                 255

 Met Gly Val Met Ser Leu Phe Leu Pro Cys Leu Trp Cys Tyr Leu
                 260                 265                 270

 Pro Ala Lys Gly Cys Leu Lys Leu Cys Gln Gly Cys Tyr Asp Arg
                 275                 280                 285

 Val Asn Arg Pro Gly Cys Arg Cys Lys Asn Ser Asn Thr Val Cys
                 290                 295                 300

 Cys Lys Val Pro Thr Val Pro Pro Arg Asn Phe Glu Lys Pro Thr
                 305                 310                 315

<210> 5703
<211> 1990
<212> DNA
<213> Homo sapien

<400> 5703
 gaattccggg ggtattggca gctgaggagt ggaggctggg cagctccgac 50

 tccctgacgc cagcgcgacc agatcaatcc aggctccagg agaaagcagg 100

 cgggcgggcg gagaaaggag aggccgagcg gctcaacccg ggccgaggct 150

 cggggagcgg agagtggcgc accgcccggc cgtccggacc cgggccgcga 200

 gaccccgctc gcccggccac tcgtgctccc gcacggacgg gcgcgccgcc 250

 aacccggtgc tgactgggtt acttttttaa acactaggaa tggtaatttc 300

 tactcttctg gacttcaaac taagaagtta aagagacttc tctgtaaata 350

 aacaaatctc ttctgctgtc cttttgcatt tggagacagc tttatttcac 400

 catatccaag gagtataact agtgctgtca ttatgaatgt gacaagttta 450

 ttttccttta caagtccagc tgtgaagaga cttcttgggt ggaaacaggg 500

 cgatgaagaa gaaaaatggg cagagaaagc tgttgatgct ttggtgaaaa 550

 aactgaagaa aaagaaaggt gccatggagg aactggaaaa ggccttgagc 600

 tgcccagggc aaccgagtaa ctgtgtcacc attccccgct ctctggatgg 650

 caggctgcaa gtctcccacc ggaagggact gcctcatgtc atttactgcc 700

 gtgtgtggcg ctggcccgat cttcagagcc accatgaact aaaaccactg 750

 gaatgctgtg agtttccttt tggttccaag cagaaggagg tctgcatcaa 800

 tccctaccac tataagagag tagaaagccc tgtacttcct cctgtgctgg 850

 ttccaagaca cagcgaatat aatcctcagc acagcctctt agctcagttc 900

 cgtaacttag gacaaaatga gcctcacatg ccactcaacg ccacttttcc 950

 agattctttc cagcaaccca acagccaccc gtttcctcac tctcccaata 1000

 gcagttaccc aaactctcct gggagcagca gcagcaccta ccctcactct 1050

 cccaccagct cagacccagg aagccctttc cagatgccag ctgatacgcc 1100

 cccacctgct tacctgcctc ctgaagaccc catgacccag gatggctctc 1150

 agccgatgga cacaaacatg atggcgcctc ccctgccctc agaaatcaac 1200

 agaggagatg ttcaggcggt tgcttatgag gaaccaaaac actggtgctc 1250

 tattgtctac tatgagctca acaatcgtgt gggtgaagcg ttccatgcct 1300

 cctccacaag tgtgttggtg gatggtttca ctgatccttc caacaataag 1350

 aaccgtttct gccttgggct gctctccaat gttaaccgga attccactat 1400

 tgaaaacacc aggcggcata ttggaaaagg agttcatctt tattatgttg 1450

 gaggggaggt gtatgccgaa tgccttagtg acagtagcat ctttgtgcaa 1500

 agtcggaact gcaactacca tcatggattt catcctacta ctgtttgcaa 1550

 gatccctagt gggtgtagtc tgaaaatttt taacaaccaa gaatttgctc 1600

 agttattggc acagtctgtg aaccatggat ttgagacagt ctatgagctt 1650

 acaaaaatgt gtactatacg tatgagcttt gtgaagggct ggggagcaga 1700

 ataccaccgc caggatgtta ctagcacccc ctgctggatt gagatacatc 1750

 tgcacggccc cctccagtgg ctggataaag ttcttactca aatgggttca 1800

 cctcataatc ctatttcatc tgtatcttaa atggccccag catctgcctc 1850

 tggaaaacta ttgagccttg catgtacttg aaggatggat gagtcagaca 1900

 cgattgagaa ctgacaaagg agccttgata atacttgacc tctgtgacca 1950

 actgttggat tcagaaattt aaacaaaaaa aaaaaaaaaa 1990

<210> 5704
<211> 465
<212> PRT
<213> Homo sapien

<400> 5704
 Met Asn Val Thr Ser Leu Phe Ser Phe Thr Ser Pro Ala Val Lys
   1               5                  10                  15

 Arg Leu Leu Gly Trp Lys Gln Gly Asp Glu Glu Glu Lys Trp Ala
                  20                  25                  30

 Glu Lys Ala Val Asp Ala Leu Val Lys Lys Leu Lys Lys Lys Lys
                  35                  40                  45

 Gly Ala Met Glu Glu Leu Glu Lys Ala Leu Ser Cys Pro Gly Gln
                  50                  55                  60

 Pro Ser Asn Cys Val Thr Ile Pro Arg Ser Leu Asp Gly Arg Leu
                  65                  70                  75

 Gln Val Ser His Arg Lys Gly Leu Pro His Val Ile Tyr Cys Arg
                  80                  85                  90

 Val Trp Arg Trp Pro Asp Leu Gln Ser His His Glu Leu Lys Pro
                  95                 100                 105

 Leu Glu Cys Cys Glu Phe Pro Phe Gly Ser Lys Gln Lys Glu Val
                 110                 115                 120

 Cys Ile Asn Pro Tyr His Tyr Lys Arg Val Glu Ser Pro Val Leu
                 125                 130                 135

 Pro Pro Val Leu Val Pro Arg His Ser Glu Tyr Asn Pro Gln His
                 140                 145                 150

 Ser Leu Leu Ala Gln Phe Arg Asn Leu Gly Gln Asn Glu Pro His
                 155                 160                 165

 Met Pro Leu Asn Ala Thr Phe Pro Asp Ser Phe Gln Gln Pro Asn
                 170                 175                 180

 Ser His Pro Phe Pro His Ser Pro Asn Ser Ser Tyr Pro Asn Ser
                 185                 190                 195

 Pro Gly Ser Ser Ser Ser Thr Tyr Pro His Ser Pro Thr Ser Ser
                 200                 205                 210

 Asp Pro Gly Ser Pro Phe Gln Met Pro Ala Asp Thr Pro Pro Pro
                 215                 220                 225

 Ala Tyr Leu Pro Pro Glu Asp Pro Met Thr Gln Asp Gly Ser Gln
                 230                 235                 240

 Pro Met Asp Thr Asn Met Met Ala Pro Pro Leu Pro Ser Glu Ile
                 245                 250                 255

 Asn Arg Gly Asp Val Gln Ala Val Ala Tyr Glu Glu Pro Lys His
                 260                 265                 270

 Trp Cys Ser Ile Val Tyr Tyr Glu Leu Asn Asn Arg Val Gly Glu
                 275                 280                 285

 Ala Phe His Ala Ser Ser Thr Ser Val Leu Val Asp Gly Phe Thr
                 290                 295                 300

 Asp Pro Ser Asn Asn Lys Asn Arg Phe Cys Leu Gly Leu Leu Ser
                 305                 310                 315

 Asn Val Asn Arg Asn Ser Thr Ile Glu Asn Thr Arg Arg His Ile
                 320                 325                 330

 Gly Lys Gly Val His Leu Tyr Tyr Val Gly Gly Glu Val Tyr Ala
                 335                 340                 345

 Glu Cys Leu Ser Asp Ser Ser Ile Phe Val Gln Ser Arg Asn Cys
                 350                 355                 360

 Asn Tyr His His Gly Phe His Pro Thr Thr Val Cys Lys Ile Pro
                 365                 370                 375

 Ser Gly Cys Ser Leu Lys Ile Phe Asn Asn Gln Glu Phe Ala Gln
                 380                 385                 390

 Leu Leu Ala Gln Ser Val Asn His Gly Phe Glu Thr Val Tyr Glu
                 395                 400                 405

 Leu Thr Lys Met Cys Thr Ile Arg Met Ser Phe Val Lys Gly Trp
                 410                 415                 420

 Gly Ala Glu Tyr His Arg Gln Asp Val Thr Ser Thr Pro Cys Trp
                 425                 430                 435

 Ile Glu Ile His Leu His Gly Pro Leu Gln Trp Leu Asp Lys Val
                 440                 445                 450

 Leu Thr Gln Met Gly Ser Pro His Asn Pro Ile Ser Ser Val Ser
                 455                 460                 465

<210> 5705
<211> 2313
<212> DNA
<213> Homo sapien

<400> 5705
 catcgcccga ggcgtccgcc ctgcaaatct gccagccccc gagaggggtt 50

 tggaacctta gcacccaagt ctaagtcaac ttcatagtgt gaacatggct 100

 acgcctcttc attcccgtcc atgccgagcc cccgactgca gcattcaaag 150

 cccccacgga ggttgagccg ggcacagaaa cacagcagcg ggagcagcaa 200

 caccagcact gccaacagac gagctcatct gcgcctttgt ttagaacgct 250

 taaaagttct gattccacta ggaccagact gcacccggca cacaacactt 300

 ggtttgctca acaaagccaa agcacacatc aagaaacttg aagaagctga 350

 aagaaaaagc cagcaccagc tcgagaattt ggaacgagaa cagagatttt 400

 taaagtggcg actggaacag ctgcagggtc ctcaggagat ggaacgaata 450

 cgaatggaca gcattggatc aactatttct tcagatcgtt ctgattcaga 500

 gcgagaggag attgaagtgg atgttgaaag cacagagttc tcccatggag 550

 aagtggacaa tataagtacc accagcatca gtgacattga tgaccacagc 600

 agcctgccga gtattgggag tgacgagggt tactccagtg ccagtgtcaa 650

 actttcattc acttcataga acccagcatg acataacagt gcagggcaaa 700

 atattcactg ggccaattca atacaaacaa tctcttaaat tgggttcatg 750

 atgcagtctc ctctttaaaa caaaacaaaa caaaactata cttgaacaaa 800

 agggtcagag gacctgtatt taagcaaata cttagcaaaa agtggggcag 850

 agcctcccaa ggagaacaaa tattcagaat attcatattg gaaaaatcac 900

 aatttttaat ggcagcagaa aacttgtgtg aaattttctt gatttgagtt 950

 gattgagaag aggacattgg agatgccatc ctctttctct tttctagttt 1000

 gctcatacta cattgagtag acacatttaa ggatggggtt atgaaccctt 1050

 cctgagcttt atggtcctaa aagcaaaata aaaactattc gaatgaaaag 1100

 acaagaaaat caggtattaa tcttggatag ctaataatga gctattaaaa 1150

 ctcagcctgg gacagtttat catgaagcct gtggatgatc aatcctttat 1200

 tattattttt tttttttgaa aaaagctcat ttcatgctct gcaaaaggag 1250

 agactcccat gaagcctttt gaaagggatc atcatgcagc tcaactttct 1300

 gttggattcc atgctaagca agctaacctt atcctgcatt gttagcacta 1350

 ggcacccagc tgccacctct ccatcctgct gcccttaggc cacatgggag 1400

 cagtccatgc atgacagcct ctatcctaca aggcctatga gtatggattg 1450

 ggggggccaa aaggaaaaag ctccatgtgc ctctttgtct gcgtgggtca 1500

 gaagagttgt gcacgcagat tagcaggcca aggtctgagc cacagcagca 1550

 tttttatttc agattttgat aactgtttat atgtgttgaa aaccaaaatg 1600

 acatcttttt aaagcttatc cataaaaaaa aatagatgtc ttttatagtg 1650

 gaaaaacaca tggggaaaaa aatcatctat tttgatgcag catttgataa 1700

 tgataaaaca cctcacacct cactctttat agtgcacaaa atgaatgagg 1750

 tctgggctag gtagaaaaag ggtcaatgct atttttgttt ttagaatcat 1800

 taccttttac cagcttttaa ccatctgata tctatagtag acacactatc 1850

 atagttaaca tagttaagtt cagcacttgt ctcattttaa tgtaaagatt 1900

 tgcttccatt ttcctacagg cagtctctct cttcctcaca gtcccactgt 1950

 gcaggtgcta ttgttactct tacgaatatt ttcagtaatg ttattttctt 2000

 ctaagtgaaa tttctagcct gcactttgat gtcatgtgtt ccctttgtct 2050

 ttcaaactcc aaggttcccc tgtggccctc tcccttaccc tgggaaggcc 2100

 tcttggagac cttacccctg gctgtttgga ctttgtatac tttaaataat 2150

 ttaactaccc ttaattactt aaaaaaaaaa aaaagcttta tgattttcat 2200

 aacttattgc tgattttaat ggattgttaa tttcagtcct gtagttttat 2250

 tttatgttta gatagggctg ggcaaggaaa aagaaaataa agacaaccat 2300

 atttagcagt gca 2313

<210> 5706
<211> 182
<212> PRT
<213> Homo sapien

<400> 5706
 Met Pro Ser Pro Arg Leu Gln His Ser Lys Pro Pro Arg Arg Leu
   1               5                  10                  15

 Ser Arg Ala Gln Lys His Ser Ser Gly Ser Ser Asn Thr Ser Thr
                  20                  25                  30

 Ala Asn Arg Arg Ala His Leu Arg Leu Cys Leu Glu Arg Leu Lys
                  35                  40                  45

 Val Leu Ile Pro Leu Gly Pro Asp Cys Thr Arg His Thr Thr Leu
                  50                  55                  60

 Gly Leu Leu Asn Lys Ala Lys Ala His Ile Lys Lys Leu Glu Glu
                  65                  70                  75

 Ala Glu Arg Lys Ser Gln His Gln Leu Glu Asn Leu Glu Arg Glu
                  80                  85                  90

 Gln Arg Phe Leu Lys Trp Arg Leu Glu Gln Leu Gln Gly Pro Gln
                  95                 100                 105

 Glu Met Glu Arg Ile Arg Met Asp Ser Ile Gly Ser Thr Ile Ser
                 110                 115                 120

 Ser Asp Arg Ser Asp Ser Glu Arg Glu Glu Ile Glu Val Asp Val
                 125                 130                 135

 Glu Ser Thr Glu Phe Ser His Gly Glu Val Asp Asn Ile Ser Thr
                 140                 145                 150

 Thr Ser Ile Ser Asp Ile Asp Asp His Ser Ser Leu Pro Ser Ile
                 155                 160                 165

 Gly Ser Asp Glu Gly Tyr Ser Ser Ala Ser Val Lys Leu Ser Phe
                 170                 175                 180

 Thr Ser


<210> 5707
<211> 911
<212> DNA
<213> Homo sapien

<400> 5707
 cccacgcgtc cggtcagagc tggagggccg ggcaccgcgg ccatggaggg 50

 tcaacgctgg ctgccgctgg aggccaatcc cgaggtcacc aaccagtttc 100

 ttaaacaatt aggtctacat cctaactggc aattcgttga tgtatatgga 150

 atggatcctg aactccttag catggtacca agaccagtct gtgcagtctt 200

 acttctcttt cctattacag aaaagtatga agtattcaga acagaagagg 250

 aagaaaaaat aaaatctcag ggacaagatg ttacatcatc agtatatttc 300

 atgaagcaaa caatcagcaa tgcctgtgga acaattggac tgattcatgc 350

 tattgcaaac aataaagaca agatgcactt tgaatctgga tcaaccttga 400

 aaaaattcct ggaggaatct gtgtcaatga gccctgaaga acgagccaga 450

 tacctggaga actatgatgc catccgagtt actcatgaga ccagtgccca 500

 tgaaggtcag actgaggcac caagtataga tgagaaagta gatcttcatt 550

 ttattgcatt agttcatgta gatgggcatc tctatgaatt agatgggcgg 600

 aagccatttc caattaacca tggtgaaact agtgatgaaa ctttattaga 650

 ggatgccata gaagtttgca agaagtttat ggagcgcgac cctgatgaac 700

 taagatttaa tgcgattgct ctttctgcag catagcttgt caataatgga 750

 aacaccaaaa actgtattat ttgcaactaa attttctctg ccatacacta 800

 actcaaaaat tttgatattt tcattaactt gatgattaaa ctttatgtga 850

 gttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 900

 aaaaaaaaaa a 911

<210> 5708
<211> 230
<212> PRT
<213> Homo sapien

<400> 5708
 Met Glu Gly Gln Arg Trp Leu Pro Leu Glu Ala Asn Pro Glu Val
   1               5                  10                  15

 Thr Asn Gln Phe Leu Lys Gln Leu Gly Leu His Pro Asn Trp Gln
                  20                  25                  30

 Phe Val Asp Val Tyr Gly Met Asp Pro Glu Leu Leu Ser Met Val
                  35                  40                  45

 Pro Arg Pro Val Cys Ala Val Leu Leu Leu Phe Pro Ile Thr Glu
                  50                  55                  60

 Lys Tyr Glu Val Phe Arg Thr Glu Glu Glu Glu Lys Ile Lys Ser
                  65                  70                  75

 Gln Gly Gln Asp Val Thr Ser Ser Val Tyr Phe Met Lys Gln Thr
                  80                  85                  90

 Ile Ser Asn Ala Cys Gly Thr Ile Gly Leu Ile His Ala Ile Ala
                  95                 100                 105

 Asn Asn Lys Asp Lys Met His Phe Glu Ser Gly Ser Thr Leu Lys
                 110                 115                 120

 Lys Phe Leu Glu Glu Ser Val Ser Met Ser Pro Glu Glu Arg Ala
                 125                 130                 135

 Arg Tyr Leu Glu Asn Tyr Asp Ala Ile Arg Val Thr His Glu Thr
                 140                 145                 150

 Ser Ala His Glu Gly Gln Thr Glu Ala Pro Ser Ile Asp Glu Lys
                 155                 160                 165

 Val Asp Leu His Phe Ile Ala Leu Val His Val Asp Gly His Leu
                 170                 175                 180

 Tyr Glu Leu Asp Gly Arg Lys Pro Phe Pro Ile Asn His Gly Glu
                 185                 190                 195

 Thr Ser Asp Glu Thr Leu Leu Glu Asp Ala Ile Glu Val Cys Lys
                 200                 205                 210

 Lys Phe Met Glu Arg Asp Pro Asp Glu Leu Arg Phe Asn Ala Ile
                 215                 220                 225

 Ala Leu Ser Ala Ala
                 230

<210> 5709
<211> 878
<212> DNA
<213> Homo sapien

<400> 5709
 cagattttca ggttgattga tgtgggacag cagccacaat gaggaactcc 50

 tatagatttc tggcatcctc tctctcagtt gtcgtttctc tcctgctaat 100

 tcctgaagat gtctgtgaaa aaattattgg aggaaatgaa gtaactcctc 150

 attcaagacc ctacatggtc ctacttagtc ttgacagaaa aaccatctgt 200

 gctggggctt tgattgcaaa agactgggtg ttgactgcag ctcactgtaa 250

 cttgaacaaa aggtcccagg tcattcttgg ggctcactca ataaccaggg 300

 aagagccaac aaaacagata atgcttgtta agaaagagtt tccctatcca 350

 tgctatgacc cagccacacg cgaaggtgac cttaaacttt tacagctgac 400

 ggaaaaagca aaaattaaca aatatgtgac tatccttcat ctacctaaaa 450

 agggggatga tgtgaaacca ggaaccatgt gccaagttgc agggtggggg 500

 aggactcaca atagtgcatc ttggtccgat actctgagag aagtcaatat 550

 caccatcata gacagaaaag tctgcaatga tcgaaatcac tataatttta 600

 accctgtgat tggaatgaat atggtttgtg ctggaagcct ccgaggtgga 650

 agagactcgt gcaatggaga ttctggaagc cctttgttgt gcgagggtgt 700

 tttccgaggg gtcacttcct ttggccttga aaataaatgc ggagaccctc 750

 gtgggcctgg tgtctatatt cttctctcaa agaaacacct caactggata 800

 attatgacta tcaagggagc agtttaaata accgtttcct ttcatttact 850

 gtggcttctt aatcttttca caaataaa 878

<210> 5710
<211> 262
<212> PRT
<213> Homo sapien

<400> 5710
 Met Arg Asn Ser Tyr Arg Phe Leu Ala Ser Ser Leu Ser Val Val
   1               5                  10                  15

 Val Ser Leu Leu Leu Ile Pro Glu Asp Val Cys Glu Lys Ile Ile
                  20                  25                  30

 Gly Gly Asn Glu Val Thr Pro His Ser Arg Pro Tyr Met Val Leu
                  35                  40                  45

 Leu Ser Leu Asp Arg Lys Thr Ile Cys Ala Gly Ala Leu Ile Ala
                  50                  55                  60

 Lys Asp Trp Val Leu Thr Ala Ala His Cys Asn Leu Asn Lys Arg
                  65                  70                  75

 Ser Gln Val Ile Leu Gly Ala His Ser Ile Thr Arg Glu Glu Pro
                  80                  85                  90

 Thr Lys Gln Ile Met Leu Val Lys Lys Glu Phe Pro Tyr Pro Cys
                  95                 100                 105

 Tyr Asp Pro Ala Thr Arg Glu Gly Asp Leu Lys Leu Leu Gln Leu
                 110                 115                 120

 Thr Glu Lys Ala Lys Ile Asn Lys Tyr Val Thr Ile Leu His Leu
                 125                 130                 135

 Pro Lys Lys Gly Asp Asp Val Lys Pro Gly Thr Met Cys Gln Val
                 140                 145                 150

 Ala Gly Trp Gly Arg Thr His Asn Ser Ala Ser Trp Ser Asp Thr
                 155                 160                 165

 Leu Arg Glu Val Asn Ile Thr Ile Ile Asp Arg Lys Val Cys Asn
                 170                 175                 180

 Asp Arg Asn His Tyr Asn Phe Asn Pro Val Ile Gly Met Asn Met
                 185                 190                 195

 Val Cys Ala Gly Ser Leu Arg Gly Gly Arg Asp Ser Cys Asn Gly
                 200                 205                 210

 Asp Ser Gly Ser Pro Leu Leu Cys Glu Gly Val Phe Arg Gly Val
                 215                 220                 225

 Thr Ser Phe Gly Leu Glu Asn Lys Cys Gly Asp Pro Arg Gly Pro
                 230                 235                 240

 Gly Val Tyr Ile Leu Leu Ser Lys Lys His Leu Asn Trp Ile Ile
                 245                 250                 255

 Met Thr Ile Lys Gly Ala Val
                 260

<210> 5711
<211> 3198
<212> DNA
<213> Homo sapien

<400> 5711
 ttgggaggag cagtctctcc gctcgtctcc cggagctttc tccattgtct 50

 ctgcctttac aacagaggga gacgatggac tgagctgatc cgcaccatgg 100

 agtctcgggt cttactgaga acattctgtt tgatcttcgg tctcggagca 150

 gtttgggggc ttggtgtgga cccttcccta cagattgacg tcttaacaga 200

 gttagaactt ggggagtcca cgaccggagt gcgtcaggtc ccggggctgc 250

 ataatgggac gaaagccttt ctctttcaag atactcccag aagcataaaa 300

 gcatccactg ctacagctga acagtttttt cagaagctga gaaataaaca 350

 tgaatttact attttggtga ccctaaaaca gacccactta aattcaggag 400

 ttattctctc aattcaccac ttggatcaca ggtacctgga actggaaagt 450

 agtggccatc ggaatgaagt cagactgcat taccgctcag gcagtcaccg 500

 ccctcacaca gaagtgtttc cttacatttt ggctgatgac aagtggcaca 550

 agctctcctt agccatcagt gcttcccatt tgattttaca cattgactgc 600

 aataaaattt atgaaagggt agtagaaaag ccctccacag acttgcctct 650

 aggcacaaca ttttggctag gacagagaaa taatgcgcat ggatatttta 700

 agggtataat gcaagatgtc caattacttg tcatgcccca gggatttatt 750

 gctcagtgcc cagatcttaa tcgcacctgt ccaacttgca atgacttcca 800

 tggacttgtg cagaaaatca tggagctaca ggatatttta gccaaaacat 850

 cagccaagct gtctcgagct gaacagcgaa tgaatagatt ggatcagtgc 900

 tattgtgaaa ggacttgcac catgaaggga accacctacc gagaatttga 950

 gtcctggata gacggctgta agaactgcac atgcctgaat ggaaccatcc 1000

 agtgtgaaac tctaatctgc ccaaatcctg actgcccact taagtcggct 1050

 cttgcgtatg tggatggcaa atgctgtaag gaatgcaaat cgatatgcca 1100

 atttcaagga cgaacctact ttgaaggaga aagaaataca gtctattcct 1150

 cttctggagt atgtgttctc tatgagtgca aggaccagac catgaaactt 1200

 gttgagagtt caggctgtcc agctttggat tgtccagagt ctcatcagat 1250

 aaccttgtct cacagctgtt gcaaagtttg taaaggttat gacttttgtt 1300

 ctgaaaggca taactgcatg gagaattcca tctgcagaaa tctgaatgac 1350

 agggctgttt gtagctgtcg agatggtttt agggctcttc gagaggataa 1400

 tgcctactgt gaagacatcg atgagtgtgc tgaagggcgc cattactgtc 1450

 gtgaaaatac aatgtgtgtc aacaccccgg gttcttttat gtgcatctgc 1500

 aaaactggat acatcagaat tgatgattat tcatgtacag aacatgatga 1550

 gtgtatcaca aatcagcaca actgtgatga aaatgcttta tgcttcaaca 1600

 ctgttggagg acacaactgt gtttgcaagc cgggctatac agggaatgga 1650

 acgacatgca aagcattttg caaagatggc tgtaggaatg gaggagcctg 1700

 tattgccgct aatgtgtgtg cctgcccaca aggcttcact ggacccagct 1750

 gtgaaacgga cattgatgaa tgctctgatg gttttgttca atgtgacagt 1800

 cgtgctaatt gcattaacct gcctggatgg taccactgtg agtgcagaga 1850

 tggctaccat gacaatggga tgttttcacc aagtggagaa tcgtgtgaag 1900

 atattgatga gtgtgggacc gggaggcaca gctgtgccaa tgataccatt 1950

 tgcttcaatt tggatggcgg atatgattgt cgatgtcctc atggaaagaa 2000

 ttgcacaggg gactgcatcc atgatggaaa agttaagcac aatggtcaga 2050

 tttgggtgtt ggaaaatgac aggtgctctg tgtgctcatg tcagaatgga 2100

 ttcgttatgt gtcgacggat ggtctgtgac tgtgagaatc ccacagttga 2150

 tcttttttgc tgccctgaat gtgacccaag gcttagtagt cagtgcctcc 2200

 atcaaaatgg ggaaactttg tataacagtg gtgacacctg ggtccagaat 2250

 tgtcaacagt gccgctgctt gcaaggggaa gttgattgtt ggcccctgcc 2300

 ttgcccagat gtggagtgtg aattcagcat tctcccagag aatgagtgct 2350

 gcccgcgctg tgtcacagac ccttgccagg ctgacaccat ccgcaatgac 2400

 atcaccaaga cttgcctgga cgaaatgaat gtggttcgct tcaccgggtc 2450

 ctcttggatc aaacatggca ctgagtgtac tctctgccag tgcaagaatg 2500

 gccacatctg ttgctcagtg gatccacagt gccttcagga actgtgaagt 2550

 taactgtctc atgggagatt tctgttaaaa gaatgttctt tcattaaaag 2600

 accaaaaaga agttaaaact taaattgggt gatttgtggg cagctaaatg 2650

 cagctttgtt aatagctgag tgaactttca attatgaaat ttgtggagct 2700

 tgacaaaatc acaaaaggaa aattactggg gcaaaattag acctcaagtc 2750

 tgcctctact gtgtctcaca tcaccatgta gaagaatggg cgtacagtat 2800

 ataccgtgac atcctgaacc ctggatagaa agcctgagcc cattggatct 2850

 gtgaaagcct ctagcttcac tggtgcagaa aattttcctc tagatcagaa 2900

 tcttcagaat cagttaggtt cctcactgca agaaataaaa tgtcaggcag 2950

 tgaatgaatt atattttcag aagtaaagca aagaagctat aacatgttat 3000

 gtacagtaca ctctgaaaag aaatctgaaa caagttattg taatgataaa 3050

 aataatgcac aggcatggtt acttaatatt ttctaacagg aaaagtcatc 3100

 cctatttcct tgttttactg cacttaatat tatttggttg aatttgttca 3150

 gtataagctc gttcttgtgc aaaattaaat aaatatttct cttacctt 3198

<210> 5712
<211> 816
<212> PRT
<213> Homo sapien

<400> 5712
 Met Glu Ser Arg Val Leu Leu Arg Thr Phe Cys Leu Ile Phe Gly
   1               5                  10                  15

 Leu Gly Ala Val Trp Gly Leu Gly Val Asp Pro Ser Leu Gln Ile
                  20                  25                  30

 Asp Val Leu Thr Glu Leu Glu Leu Gly Glu Ser Thr Thr Gly Val
                  35                  40                  45

 Arg Gln Val Pro Gly Leu His Asn Gly Thr Lys Ala Phe Leu Phe
                  50                  55                  60

 Gln Asp Thr Pro Arg Ser Ile Lys Ala Ser Thr Ala Thr Ala Glu
                  65                  70                  75

 Gln Phe Phe Gln Lys Leu Arg Asn Lys His Glu Phe Thr Ile Leu
                  80                  85                  90

 Val Thr Leu Lys Gln Thr His Leu Asn Ser Gly Val Ile Leu Ser
                  95                 100                 105

 Ile His His Leu Asp His Arg Tyr Leu Glu Leu Glu Ser Ser Gly
                 110                 115                 120

 His Arg Asn Glu Val Arg Leu His Tyr Arg Ser Gly Ser His Arg
                 125                 130                 135

 Pro His Thr Glu Val Phe Pro Tyr Ile Leu Ala Asp Asp Lys Trp
                 140                 145                 150

 His Lys Leu Ser Leu Ala Ile Ser Ala Ser His Leu Ile Leu His
                 155                 160                 165

 Ile Asp Cys Asn Lys Ile Tyr Glu Arg Val Val Glu Lys Pro Ser
                 170                 175                 180

 Thr Asp Leu Pro Leu Gly Thr Thr Phe Trp Leu Gly Gln Arg Asn
                 185                 190                 195

 Asn Ala His Gly Tyr Phe Lys Gly Ile Met Gln Asp Val Gln Leu
                 200                 205                 210

 Leu Val Met Pro Gln Gly Phe Ile Ala Gln Cys Pro Asp Leu Asn
                 215                 220                 225

 Arg Thr Cys Pro Thr Cys Asn Asp Phe His Gly Leu Val Gln Lys
                 230                 235                 240

 Ile Met Glu Leu Gln Asp Ile Leu Ala Lys Thr Ser Ala Lys Leu
                 245                 250                 255

 Ser Arg Ala Glu Gln Arg Met Asn Arg Leu Asp Gln Cys Tyr Cys
                 260                 265                 270

 Glu Arg Thr Cys Thr Met Lys Gly Thr Thr Tyr Arg Glu Phe Glu
                 275                 280                 285

 Ser Trp Ile Asp Gly Cys Lys Asn Cys Thr Cys Leu Asn Gly Thr
                 290                 295                 300

 Ile Gln Cys Glu Thr Leu Ile Cys Pro Asn Pro Asp Cys Pro Leu
                 305                 310                 315

 Lys Ser Ala Leu Ala Tyr Val Asp Gly Lys Cys Cys Lys Glu Cys
                 320                 325                 330

 Lys Ser Ile Cys Gln Phe Gln Gly Arg Thr Tyr Phe Glu Gly Glu
                 335                 340                 345

 Arg Asn Thr Val Tyr Ser Ser Ser Gly Val Cys Val Leu Tyr Glu
                 350                 355                 360

 Cys Lys Asp Gln Thr Met Lys Leu Val Glu Ser Ser Gly Cys Pro
                 365                 370                 375

 Ala Leu Asp Cys Pro Glu Ser His Gln Ile Thr Leu Ser His Ser
                 380                 385                 390

 Cys Cys Lys Val Cys Lys Gly Tyr Asp Phe Cys Ser Glu Arg His
                 395                 400                 405

 Asn Cys Met Glu Asn Ser Ile Cys Arg Asn Leu Asn Asp Arg Ala
                 410                 415                 420

 Val Cys Ser Cys Arg Asp Gly Phe Arg Ala Leu Arg Glu Asp Asn
                 425                 430                 435

 Ala Tyr Cys Glu Asp Ile Asp Glu Cys Ala Glu Gly Arg His Tyr
                 440                 445                 450

 Cys Arg Glu Asn Thr Met Cys Val Asn Thr Pro Gly Ser Phe Met
                 455                 460                 465

 Cys Ile Cys Lys Thr Gly Tyr Ile Arg Ile Asp Asp Tyr Ser Cys
                 470                 475                 480

 Thr Glu His Asp Glu Cys Ile Thr Asn Gln His Asn Cys Asp Glu
                 485                 490                 495

 Asn Ala Leu Cys Phe Asn Thr Val Gly Gly His Asn Cys Val Cys
                 500                 505                 510

 Lys Pro Gly Tyr Thr Gly Asn Gly Thr Thr Cys Lys Ala Phe Cys
                 515                 520                 525

 Lys Asp Gly Cys Arg Asn Gly Gly Ala Cys Ile Ala Ala Asn Val
                 530                 535                 540

 Cys Ala Cys Pro Gln Gly Phe Thr Gly Pro Ser Cys Glu Thr Asp
                 545                 550                 555

 Ile Asp Glu Cys Ser Asp Gly Phe Val Gln Cys Asp Ser Arg Ala
                 560                 565                 570

 Asn Cys Ile Asn Leu Pro Gly Trp Tyr His Cys Glu Cys Arg Asp
                 575                 580                 585

 Gly Tyr His Asp Asn Gly Met Phe Ser Pro Ser Gly Glu Ser Cys
                 590                 595                 600

 Glu Asp Ile Asp Glu Cys Gly Thr Gly Arg His Ser Cys Ala Asn
                 605                 610                 615

 Asp Thr Ile Cys Phe Asn Leu Asp Gly Gly Tyr Asp Cys Arg Cys
                 620                 625                 630

 Pro His Gly Lys Asn Cys Thr Gly Asp Cys Ile His Asp Gly Lys
                 635                 640                 645

 Val Lys His Asn Gly Gln Ile Trp Val Leu Glu Asn Asp Arg Cys
                 650                 655                 660

 Ser Val Cys Ser Cys Gln Asn Gly Phe Val Met Cys Arg Arg Met
                 665                 670                 675

 Val Cys Asp Cys Glu Asn Pro Thr Val Asp Leu Phe Cys Cys Pro
                 680                 685                 690

 Glu Cys Asp Pro Arg Leu Ser Ser Gln Cys Leu His Gln Asn Gly
                 695                 700                 705

 Glu Thr Leu Tyr Asn Ser Gly Asp Thr Trp Val Gln Asn Cys Gln
                 710                 715                 720

 Gln Cys Arg Cys Leu Gln Gly Glu Val Asp Cys Trp Pro Leu Pro
                 725                 730                 735

 Cys Pro Asp Val Glu Cys Glu Phe Ser Ile Leu Pro Glu Asn Glu
                 740                 745                 750

 Cys Cys Pro Arg Cys Val Thr Asp Pro Cys Gln Ala Asp Thr Ile
                 755                 760                 765

 Arg Asn Asp Ile Thr Lys Thr Cys Leu Asp Glu Met Asn Val Val
                 770                 775                 780

 Arg Phe Thr Gly Ser Ser Trp Ile Lys His Gly Thr Glu Cys Thr
                 785                 790                 795

 Leu Cys Gln Cys Lys Asn Gly His Ile Cys Cys Ser Val Asp Pro
                 800                 805                 810

 Gln Cys Leu Gln Glu Leu
                 815

<210> 5713
<211> 2439
<212> DNA
<213> Homo sapien

<400> 5713
 gcagccgcca ccgccgccgc cgccgccacc agagccgccc tgtccgcgcc 50

 gcgcctcggc agccggaaca gggccgccgt cggggagccc caacacacgg 100

 tccacagctc atcatgatgg acttggagct gccgccgccg ggactcccgt 150

 cccagcagga catggatttg attgacatac tttggaggca agatatagat 200

 cttggagtaa gtcgagaagt atttgacttc agtcagcgac ggaaagagta 250

 tgagctggaa aaacagaaaa aacttgaaaa ggaaagacaa gaacaactcc 300

 aaaaggagca agagaaagcc tttttcgctc agttacaact agatgaagag 350

 acaggtgaat ttctcccaat tcagccagcc cagcacatcc agtcagaaac 400

 cagtggatct gccaactact cccaggttgc ccacattccc aaatcagatg 450

 ctttgtactt tgatgactgc atgcagcttt tggcgcagac attcccgttt 500

 gtagatgaca atgaggtttc ttcggctacg tttcagtcac ttgttcctga 550

 tattcccggt cacatcgaga gcccagtctt cattgctact aatcaggctc 600

 agtcacctga aacttctgtt gctcaggtag cccctgttga tttagacggt 650

 atgcaacagg acattgagca agtttgggag gagctattat ccattcctga 700

 gttacagtgt cttaatattg aaaatgacaa gctggttgag actaccatgg 750

 ttccaagtcc agaagccaaa ctgacagaag ttgacaatta tcatttttac 800

 tcatctatac cctcaatgga aaaagaagta ggtaactgta gtccacattt 850

 tcttaatgct tttgaggatt ccttcagcag catcctctcc acagaagacc 900

 ccaaccagtt gacagtgaac tcattaaatt cagatgccac agtcaacaca 950

 gattttggtg atgaatttta ttctgctttc atagctgagc ccagtatcag 1000

 caacagcatg ccctcacctg ctactttaag ccattcactc tctgaacttc 1050

 taaatgggcc cattgatgtt tctgatctat cactttgcaa agctttcaac 1100

 caaaaccacc ctgaaagcac agcagaattc aatgattctg actccggcat 1150

 ttcactaaac acaagtccca gtgtggcatc accagaacac tcagtggaat 1200

 cttccagcta tggagacaca ctacttggcc tcagtgattc tgaagtggaa 1250

 gagctagata gtgcccctgg aagtgtcaaa cagaatggtc ctaaaacacc 1300

 agtacattct tctggggata tggtacaacc cttgtcacca tctcaggggc 1350

 agagcactca cgtgcatgat gcccaatgtg agaacacacc agagaaagaa 1400

 ttgcctgtaa gtcctggtca tcggaaaacc ccattcacaa aagacaaaca 1450

 ttcaagccgc ttggaggctc atctcacaag agatgaactt agggcaaaag 1500

 ctctccatat cccattccct gtagaaaaaa tcattaacct ccctgttgtt 1550

 gacttcaacg aaatgatgtc caaagagcag ttcaatgaag ctcaacttgc 1600

 attaattcgg gatatacgta ggaggggtaa gaataaagtg gctgctcaga 1650

 attgcagaaa aagaaaactg gaaaatatag tagaactaga gcaagattta 1700

 gatcatttga aagatgaaaa agaaaaattg ctcaaagaaa aaggagaaaa 1750

 tgacaaaagc cttcacctac tgaaaaaaca actcagcacc ttatatctcg 1800

 aagttttcag catgctacgt gatgaagatg gaaaacctta ttctcctagt 1850

 gaatactccc tgcagcaaac aagagatggc aatgttttcc ttgttcccaa 1900

 aagtaagaag ccagatgtta agaaaaacta gatttaggag gatttgacct 1950

 tttctgagct agtttttttg tactattata ctaaaagctc ctactgtgat 2000

 gtgaaatgct catactttat aagtaattct atgcaaaatc atagccaaaa 2050

 ctagtataga aaataatacg aaactttaaa aagcattgga gtgtcagtat 2100

 gttgaatcag tagtttcact ttaactgtaa acaatttctt aggacaccat 2150

 ttgggctagt ttctgtgtaa gtgtaaatac tacaaaaact tatttatact 2200

 gttcttatgt catttgttat attcatagat ttatatgatg atatgacatc 2250

 tggctaaaaa gaaattattg caaaactaac cactatgtac ttttttataa 2300

 atactgtatg gacaaaaaat ggcatttttt atattaaatt gtttagctct 2350

 ggcaaaaaaa aaaaatttta agagctggta ctaataaagg attattatga 2400

 ctgttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 2439

<210> 5714
<211> 605
<212> PRT
<213> Homo sapien

<400> 5714
 Met Met Asp Leu Glu Leu Pro Pro Pro Gly Leu Pro Ser Gln Gln
   1               5                  10                  15

 Asp Met Asp Leu Ile Asp Ile Leu Trp Arg Gln Asp Ile Asp Leu
                  20                  25                  30

 Gly Val Ser Arg Glu Val Phe Asp Phe Ser Gln Arg Arg Lys Glu
                  35                  40                  45

 Tyr Glu Leu Glu Lys Gln Lys Lys Leu Glu Lys Glu Arg Gln Glu
                  50                  55                  60

 Gln Leu Gln Lys Glu Gln Glu Lys Ala Phe Phe Ala Gln Leu Gln
                  65                  70                  75

 Leu Asp Glu Glu Thr Gly Glu Phe Leu Pro Ile Gln Pro Ala Gln
                  80                  85                  90

 His Ile Gln Ser Glu Thr Ser Gly Ser Ala Asn Tyr Ser Gln Val
                  95                 100                 105

 Ala His Ile Pro Lys Ser Asp Ala Leu Tyr Phe Asp Asp Cys Met
                 110                 115                 120

 Gln Leu Leu Ala Gln Thr Phe Pro Phe Val Asp Asp Asn Glu Val
                 125                 130                 135

 Ser Ser Ala Thr Phe Gln Ser Leu Val Pro Asp Ile Pro Gly His
                 140                 145                 150

 Ile Glu Ser Pro Val Phe Ile Ala Thr Asn Gln Ala Gln Ser Pro
                 155                 160                 165

 Glu Thr Ser Val Ala Gln Val Ala Pro Val Asp Leu Asp Gly Met
                 170                 175                 180

 Gln Gln Asp Ile Glu Gln Val Trp Glu Glu Leu Leu Ser Ile Pro
                 185                 190                 195

 Glu Leu Gln Cys Leu Asn Ile Glu Asn Asp Lys Leu Val Glu Thr
                 200                 205                 210

 Thr Met Val Pro Ser Pro Glu Ala Lys Leu Thr Glu Val Asp Asn
                 215                 220                 225

 Tyr His Phe Tyr Ser Ser Ile Pro Ser Met Glu Lys Glu Val Gly
                 230                 235                 240

 Asn Cys Ser Pro His Phe Leu Asn Ala Phe Glu Asp Ser Phe Ser
                 245                 250                 255

 Ser Ile Leu Ser Thr Glu Asp Pro Asn Gln Leu Thr Val Asn Ser
                 260                 265                 270

 Leu Asn Ser Asp Ala Thr Val Asn Thr Asp Phe Gly Asp Glu Phe
                 275                 280                 285

 Tyr Ser Ala Phe Ile Ala Glu Pro Ser Ile Ser Asn Ser Met Pro
                 290                 295                 300

 Ser Pro Ala Thr Leu Ser His Ser Leu Ser Glu Leu Leu Asn Gly
                 305                 310                 315

 Pro Ile Asp Val Ser Asp Leu Ser Leu Cys Lys Ala Phe Asn Gln
                 320                 325                 330

 Asn His Pro Glu Ser Thr Ala Glu Phe Asn Asp Ser Asp Ser Gly
                 335                 340                 345

 Ile Ser Leu Asn Thr Ser Pro Ser Val Ala Ser Pro Glu His Ser
                 350                 355                 360

 Val Glu Ser Ser Ser Tyr Gly Asp Thr Leu Leu Gly Leu Ser Asp
                 365                 370                 375

 Ser Glu Val Glu Glu Leu Asp Ser Ala Pro Gly Ser Val Lys Gln
                 380                 385                 390

 Asn Gly Pro Lys Thr Pro Val His Ser Ser Gly Asp Met Val Gln
                 395                 400                 405

 Pro Leu Ser Pro Ser Gln Gly Gln Ser Thr His Val His Asp Ala
                 410                 415                 420

 Gln Cys Glu Asn Thr Pro Glu Lys Glu Leu Pro Val Ser Pro Gly
                 425                 430                 435

 His Arg Lys Thr Pro Phe Thr Lys Asp Lys His Ser Ser Arg Leu
                 440                 445                 450

 Glu Ala His Leu Thr Arg Asp Glu Leu Arg Ala Lys Ala Leu His
                 455                 460                 465

 Ile Pro Phe Pro Val Glu Lys Ile Ile Asn Leu Pro Val Val Asp
                 470                 475                 480

 Phe Asn Glu Met Met Ser Lys Glu Gln Phe Asn Glu Ala Gln Leu
                 485                 490                 495

 Ala Leu Ile Arg Asp Ile Arg Arg Arg Gly Lys Asn Lys Val Ala
                 500                 505                 510

 Ala Gln Asn Cys Arg Lys Arg Lys Leu Glu Asn Ile Val Glu Leu
                 515                 520                 525

 Glu Gln Asp Leu Asp His Leu Lys Asp Glu Lys Glu Lys Leu Leu
                 530                 535                 540

 Lys Glu Lys Gly Glu Asn Asp Lys Ser Leu His Leu Leu Lys Lys
                 545                 550                 555

 Gln Leu Ser Thr Leu Tyr Leu Glu Val Phe Ser Met Leu Arg Asp
                 560                 565                 570

 Glu Asp Gly Lys Pro Tyr Ser Pro Ser Glu Tyr Ser Leu Gln Gln
                 575                 580                 585

 Thr Arg Asp Gly Asn Val Phe Leu Val Pro Lys Ser Lys Lys Pro
                 590                 595                 600

 Asp Val Lys Lys Asn
                 605

<210> 5715
<211> 4426
<212> DNA
<213> Homo sapien

<400> 5715
 tgccttgacc aggacttggg actttgcgaa aggatcgcgg ggcccggaga 50

 ggtgttggag agcacaatgg ctgaacaagt ccttcctcag gctttgtatt 100

 tgagcaatat gcggaaagct gtgaagatac gggagagaac tccagaagac 150

 atttttaaac ctactaatgg gatcattcat cattttaaaa ccatgcaccg 200

 atacacactg gaaatgttca gaacttgcca gttttgtcct cagtttcggg 250

 agatcatcca caaagccctc atcgacagaa acatccaggc caccctggaa 300

 agccagaaga aactcaactg gtgtcgagaa gtccggaagc ttgtggcgct 350

 gaaaacgaac ggtgacggca attgcctcat gcatgccact tctcagtaca 400

 tgtggggcgt tcaggacaca gacttggtac tgaggaaggc gctgttcagc 450

 acgctcaagg aaacagacac acgcaacttt aaattccgct ggcaactgga 500

 gtctctcaaa tctcaggaat ttgttgaaac ggggctttgc tatgatactc 550

 ggaactggaa tgatgaatgg gacaatctta tcaaaatggc ttccacagac 600

 acacccatgg cccgaagtgg acttcagtac aactcactgg aagaaataca 650

 catatttgtc ctttgcaaca tcctcagaag gccaatcatt gtcatttcag 700

 acaaaatgct aagaagtttg gaatcaggtt ccaatttcgc ccctttgaaa 750

 gtgggtggaa tttacttgcc tctccactgg cctgcccagg aatgctacag 800

 ataccccatt gttctcggct atgacagcca tcattttgta cccttggtga 850

 ccctgaagga cagtgggcct gaaatccgag ctgttccact tgttaacaga 900

 gaccggggaa gatttgaaga cttaaaagtt cactttttga cagatcctga 950

 aaatgagatg aaggagaagc tcttaaaaga gtacttaatg gtgatagaaa 1000

 tccccgtcca aggctgggac catggcacaa ctcatctcat caatgccgca 1050

 aagttggatg aagctaactt accaaaagaa atcaatctgg tagatgatta 1100

 ctttgaactt gttcagcatg agtacaagaa atggcaggaa aacagcgagc 1150

 aggggaggag agaggggcac gcccagaatc ccatggaacc ttccgtgccc 1200

 cagctttctc tcatggatgt aaaatgtgaa acgcccaact gccccttctt 1250

 catgtctgtg aacacccagc ctttatgcca tgagtgctca gagaggcggc 1300

 aaaagaatca aaacaaactc ccaaagctga actccaagcc gggccctgag 1350

 gggctccctg gcatggcgct cggggcctct cggggagaag cctatgagcc 1400

 cttggcgtgg aaccctgagg agtccactgg ggggcctcat tcggccccac 1450

 cgacagcacc cagccctttt ctgttcagtg agaccactgc catgaagtgc 1500

 aggagccccg gctgcccctt cacactgaat gtgcagcaca acggattttg 1550

 tgaacgttgc cacaacgccc ggcaacttca cgccagccac gccccagacc 1600

 acacaaggca cttggatccc gggaagtgcc aagcctgcct ccaggatgtt 1650

 accaggacat ttaatgggat ctgcagtact tgcttcaaaa ggactacagc 1700

 agaggcctcc tccagcctca gcaccagcct ccctccttcc tgtcaccagc 1750

 gttccaagtc agatccctcg cggctcgtcc ggagcccctc cccgcattct 1800

 tgccacagag ctggaaacga cgcccctgct ggctgcctgt ctcaagctgc 1850

 acggactcct ggggacagga cggggacgag caagtgcaga aaagccggct 1900

 gcgtgtattt tgggactcca gaaaacaagg gcttttgcac actgtgtttc 1950

 atcgagtaca gagaaaacaa acattttgct gctgcctcag ggaaagtcag 2000

 tcccacagcg tccaggttcc agaacaccat tccgtgcctg gggagggaat 2050

 gcggcaccct tggaagcacc atgtttgaag gatactgcca gaagtgtttc 2100

 attgaagctc agaatcagag atttcatgag gccaaaagga cagaagagca 2150

 actgagatcg agccagcgca gagatgtgcc tcgaaccaca caaagcacct 2200

 caaggcccaa gtgcgcccgg gcctcctgca agaacatcct ggcctgccgc 2250

 agcgaggagc tctgcatgga gtgtcagcat cccaaccaga ggatgggccc 2300

 tggggcccac cggggtgagc ctgcccccga agaccccccc aagcagcgtt 2350

 gccgggcccc cgcctgtgat cattttggca atgccaagtg caacggctac 2400

 tgcaacgaat gctttcagtt caagcagatg tatggctaac cggaaacagg 2450

 tgggtcacct cctgcaagaa gtggggcctc gagctgtcag tcatcatggt 2500

 gctatcctct gaacccctca gctgccactg caacagtggg cttaagggtg 2550

 tctgagcagg agaggaaaga taagctcttc gtggtgccca cgatgctcag 2600

 gtttggtaac ccgggagtgt tcccaggtgg ccttagaaag caaagcttgt 2650

 aactggcaag ggatgatgtc agattcagcc caaggttcct cctctcctac 2700

 caagcaggag gccaggaact tctttggact tggaaggtgt gcggggactg 2750

 gccgaggccc ctgcaccctg cgcatcagga ctgcttcatc gtcttggctg 2800

 agaaagggaa aagacacaca agtcgcgtgg gttggagaag ccagagccat 2850

 tccacctccc ctcccccagc atctctcaga gatgtgaagc cagatcctca 2900

 tggcagcgag gccctctgca agaagctcaa ggaagctcag ggaaaatgga 2950

 cgtattcaga gagtgtttgt agttcatggt ttttccctac ctgcccggtt 3000

 cctttcctga ggacccggca gaaatgcaga accatccatg gactgtgatt 3050

 ctgaggctgc tgagactgaa catgttcaca ttgacagaaa aacaagctgc 3100

 tctttataat atgcaccttt taaaaaatta gaatatttta ctgggaagac 3150

 gtgtaactct ttgggttatt actgtcttta cttctaaaga agttagcttg 3200

 aactgaggag taaaagtgtg tacatatata atataccctt acattatgta 3250

 tgagggattt ttttaaatta tattgaaatg ctgccctaga agtacaatag 3300

 gaaggctaaa taataataac ctgttttctg gttgttgttg gggcatgagc 3350

 ttgtgtatac actgcttgca taaactcaac cagctgcctt tttaaaggga 3400

 gctctagtcc tttttgtgta attcacttta tttattttat tacaaacttc 3450

 aagattattt aagtgaagat atttcttcag ctctggggaa aatgccacag 3500

 tgttctcctg agagaacatc cttgctttga gtcaggctgt gggcaagttc 3550

 ctgaccacag ggagtaaatt ggcctctttg atacactttt gcttgcctcc 3600

 ccaggaaaga aggaattgca tccaaggtat acatacatat tcatcgatgt 3650

 ttcgtgcttc tccttatgaa actccagcta tgtaataaaa aactatactc 3700

 tgtgttctgt taatgcctct gagtgtccta cctccttgga gatgagatag 3750

 ggaaggagca gggatgagac tggcaatggt cacagggaaa gatgtggcct 3800

 tttgtgatgg ttttattttc tgttaacact gtgtcctggg ggggctggga 3850

 agtcccctgc atcccatggt accctggtat tgggacagca aaagccagta 3900

 accatgagta tgaggaaatc tctttctgtt gctggcttac agtttctctg 3950

 tgtgctttgt ggttgctgtc atatttgctc tagaagaaaa aaaaaaaagg 4000

 aggggaaatg cattttcccc agagataaag gctgccattt tgggggtctg 4050

 tacttatggc ctgaaaatat ttgtgatcca taactctaca cagcctttac 4100

 tcatactatt aggcacactt tccccttaga gccccctaag tttttcccag 4150

 acgaatcttt ataatttcct ttccaaagat accaaataaa cttcagtgtt 4200

 ttcatctaat tctcttaaag ttgatatctt aatattttgt gttgatcatt 4250

 atttccattc ttaatgtgaa aaaaagtaat tatttatact tattataaaa 4300

 agtatttgaa atttgcacat ttaattgtcc ctaatagaaa gccacctatt 4350

 ctttgttgga tttcttcaag tttttctaaa taaatgtaac ttttcacaag 4400

 agtcaacatt aaaaaataaa ttattt 4426

<210> 5716
<211> 790
<212> PRT
<213> Homo sapien

<400> 5716
 Met Ala Glu Gln Val Leu Pro Gln Ala Leu Tyr Leu Ser Asn Met
   1               5                  10                  15

 Arg Lys Ala Val Lys Ile Arg Glu Arg Thr Pro Glu Asp Ile Phe
                  20                  25                  30

 Lys Pro Thr Asn Gly Ile Ile His His Phe Lys Thr Met His Arg
                  35                  40                  45

 Tyr Thr Leu Glu Met Phe Arg Thr Cys Gln Phe Cys Pro Gln Phe
                  50                  55                  60

 Arg Glu Ile Ile His Lys Ala Leu Ile Asp Arg Asn Ile Gln Ala
                  65                  70                  75

 Thr Leu Glu Ser Gln Lys Lys Leu Asn Trp Cys Arg Glu Val Arg
                  80                  85                  90

 Lys Leu Val Ala Leu Lys Thr Asn Gly Asp Gly Asn Cys Leu Met
                  95                 100                 105

 His Ala Thr Ser Gln Tyr Met Trp Gly Val Gln Asp Thr Asp Leu
                 110                 115                 120

 Val Leu Arg Lys Ala Leu Phe Ser Thr Leu Lys Glu Thr Asp Thr
                 125                 130                 135

 Arg Asn Phe Lys Phe Arg Trp Gln Leu Glu Ser Leu Lys Ser Gln
                 140                 145                 150

 Glu Phe Val Glu Thr Gly Leu Cys Tyr Asp Thr Arg Asn Trp Asn
                 155                 160                 165

 Asp Glu Trp Asp Asn Leu Ile Lys Met Ala Ser Thr Asp Thr Pro
                 170                 175                 180

 Met Ala Arg Ser Gly Leu Gln Tyr Asn Ser Leu Glu Glu Ile His
                 185                 190                 195

 Ile Phe Val Leu Cys Asn Ile Leu Arg Arg Pro Ile Ile Val Ile
                 200                 205                 210

 Ser Asp Lys Met Leu Arg Ser Leu Glu Ser Gly Ser Asn Phe Ala
                 215                 220                 225

 Pro Leu Lys Val Gly Gly Ile Tyr Leu Pro Leu His Trp Pro Ala
                 230                 235                 240

 Gln Glu Cys Tyr Arg Tyr Pro Ile Val Leu Gly Tyr Asp Ser His
                 245                 250                 255

 His Phe Val Pro Leu Val Thr Leu Lys Asp Ser Gly Pro Glu Ile
                 260                 265                 270

 Arg Ala Val Pro Leu Val Asn Arg Asp Arg Gly Arg Phe Glu Asp
                 275                 280                 285

 Leu Lys Val His Phe Leu Thr Asp Pro Glu Asn Glu Met Lys Glu
                 290                 295                 300

 Lys Leu Leu Lys Glu Tyr Leu Met Val Ile Glu Ile Pro Val Gln
                 305                 310                 315

 Gly Trp Asp His Gly Thr Thr His Leu Ile Asn Ala Ala Lys Leu
                 320                 325                 330

 Asp Glu Ala Asn Leu Pro Lys Glu Ile Asn Leu Val Asp Asp Tyr
                 335                 340                 345

 Phe Glu Leu Val Gln His Glu Tyr Lys Lys Trp Gln Glu Asn Ser
                 350                 355                 360

 Glu Gln Gly Arg Arg Glu Gly His Ala Gln Asn Pro Met Glu Pro
                 365                 370                 375

 Ser Val Pro Gln Leu Ser Leu Met Asp Val Lys Cys Glu Thr Pro
                 380                 385                 390

 Asn Cys Pro Phe Phe Met Ser Val Asn Thr Gln Pro Leu Cys His
                 395                 400                 405

 Glu Cys Ser Glu Arg Arg Gln Lys Asn Gln Asn Lys Leu Pro Lys
                 410                 415                 420

 Leu Asn Ser Lys Pro Gly Pro Glu Gly Leu Pro Gly Met Ala Leu
                 425                 430                 435

 Gly Ala Ser Arg Gly Glu Ala Tyr Glu Pro Leu Ala Trp Asn Pro
                 440                 445                 450

 Glu Glu Ser Thr Gly Gly Pro His Ser Ala Pro Pro Thr Ala Pro
                 455                 460                 465

 Ser Pro Phe Leu Phe Ser Glu Thr Thr Ala Met Lys Cys Arg Ser
                 470                 475                 480

 Pro Gly Cys Pro Phe Thr Leu Asn Val Gln His Asn Gly Phe Cys
                 485                 490                 495

 Glu Arg Cys His Asn Ala Arg Gln Leu His Ala Ser His Ala Pro
                 500                 505                 510

 Asp His Thr Arg His Leu Asp Pro Gly Lys Cys Gln Ala Cys Leu
                 515                 520                 525

 Gln Asp Val Thr Arg Thr Phe Asn Gly Ile Cys Ser Thr Cys Phe
                 530                 535                 540

 Lys Arg Thr Thr Ala Glu Ala Ser Ser Ser Leu Ser Thr Ser Leu
                 545                 550                 555

 Pro Pro Ser Cys His Gln Arg Ser Lys Ser Asp Pro Ser Arg Leu
                 560                 565                 570

 Val Arg Ser Pro Ser Pro His Ser Cys His Arg Ala Gly Asn Asp
                 575                 580                 585

 Ala Pro Ala Gly Cys Leu Ser Gln Ala Ala Arg Thr Pro Gly Asp
                 590                 595                 600

 Arg Thr Gly Thr Ser Lys Cys Arg Lys Ala Gly Cys Val Tyr Phe
                 605                 610                 615

 Gly Thr Pro Glu Asn Lys Gly Phe Cys Thr Leu Cys Phe Ile Glu
                 620                 625                 630

 Tyr Arg Glu Asn Lys His Phe Ala Ala Ala Ser Gly Lys Val Ser
                 635                 640                 645

 Pro Thr Ala Ser Arg Phe Gln Asn Thr Ile Pro Cys Leu Gly Arg
                 650                 655                 660

 Glu Cys Gly Thr Leu Gly Ser Thr Met Phe Glu Gly Tyr Cys Gln
                 665                 670                 675

 Lys Cys Phe Ile Glu Ala Gln Asn Gln Arg Phe His Glu Ala Lys
                 680                 685                 690

 Arg Thr Glu Glu Gln Leu Arg Ser Ser Gln Arg Arg Asp Val Pro
                 695                 700                 705

 Arg Thr Thr Gln Ser Thr Ser Arg Pro Lys Cys Ala Arg Ala Ser
                 710                 715                 720

 Cys Lys Asn Ile Leu Ala Cys Arg Ser Glu Glu Leu Cys Met Glu
                 725                 730                 735

 Cys Gln His Pro Asn Gln Arg Met Gly Pro Gly Ala His Arg Gly
                 740                 745                 750

 Glu Pro Ala Pro Glu Asp Pro Pro Lys Gln Arg Cys Arg Ala Pro
                 755                 760                 765

 Ala Cys Asp His Phe Gly Asn Ala Lys Cys Asn Gly Tyr Cys Asn
                 770                 775                 780

 Glu Cys Phe Gln Phe Lys Gln Met Tyr Gly
                 785                 790

<210> 5717
<211> 1287
<212> DNA
<213> Homo sapien

<400> 5717
 ccctttcgct gcggcctttc cccaacccgg acccggcact tctcgggttc 50

 cgcgactgcc gatcgccccg gcgcggcacc gctccctcag gagtcgccta 100

 ggccgcgcag tctcccgact tctcgtcagg ctttcgcgcc ggcgctccag 150

 caatcactgg ctggagaagg tgggcgttcc ggctcgagag gaccctgccg 200

 cggctccgga agagcctcgt cctgggcggc ggtggtgcgg cggtcgccgt 250

 tatggccact gggctgggcg gctgaccgcg ggctaggaaa gggcccaggg 300

 cccgaatctc ggtggccgct gctccagcgc ggcctgcgcc atggcctcct 350

 ccgccgcctc ctcggagcat ttcgagaagc tgcacgagat cttccgcggc 400

 ctccatgaag acctacaagg ggtgcccgag cggctgctgg ggacggcggg 450

 gaccgaagaa aagaagaaat tgatcaggga ttttgatgaa aagcaacagg 500

 aagcaaatga aacgctggca gagatggagg aggagctacg ttatgcaccc 550

 ctgtctttcc gaaaccccat gatgtctaag cttcgaaact accggaagga 600

 ccttgctaaa ctccatcggg aggtgagaag cacacctttg acagccacac 650

 ctggaggccg aggagacatg aaatatggca tatatgctgt agagaatgag 700

 catatgaatc ggctacagtc tcaaagggca atgcttctgc agggcactga 750

 aagcctgaac cgggccaccc aaagtattga acgttctcat cggattgcca 800

 cagagactga ccagattggc tcagaaatca tagaagagct gggggaacaa 850

 cgagaccagt tagaacgtac caagagtaga ctggtaaaca caagtgaaaa 900

 cttgagcaaa agtcggaaga ttctccgttc aatgtccaga aaagtgacaa 950

 ccaacaagct gctgctttcc attatcatct tactggagct cgccatcctg 1000

 ggaggcctgg tttactacaa attctttcgc agccattgaa cttctatagg 1050

 gaagggtttg tggaccagaa ctttgacctt gtgaatgcat gatgttaggg 1100

 atgtggatag aataagcata ttgctgctgt gggctgacag ttcaaggatg 1150

 cactgtatag ccaggctgtg ggaggaggga ggaaagatga aaaaccactt 1200

 aaatgtgaag gaacaacagc aacaagacca gtatgatata ccaaggtaat 1250

 aaatgctgtt tatgacttct ttaaaaaaaa aaaaaaa 1287

<210> 5718
<211> 232
<212> PRT
<213> Homo sapien

<400> 5718
 Met Ala Ser Ser Ala Ala Ser Ser Glu His Phe Glu Lys Leu His
   1               5                  10                  15

 Glu Ile Phe Arg Gly Leu His Glu Asp Leu Gln Gly Val Pro Glu
                  20                  25                  30

 Arg Leu Leu Gly Thr Ala Gly Thr Glu Glu Lys Lys Lys Leu Ile
                  35                  40                  45

 Arg Asp Phe Asp Glu Lys Gln Gln Glu Ala Asn Glu Thr Leu Ala
                  50                  55                  60

 Glu Met Glu Glu Glu Leu Arg Tyr Ala Pro Leu Ser Phe Arg Asn
                  65                  70                  75

 Pro Met Met Ser Lys Leu Arg Asn Tyr Arg Lys Asp Leu Ala Lys
                  80                  85                  90

 Leu His Arg Glu Val Arg Ser Thr Pro Leu Thr Ala Thr Pro Gly
                  95                 100                 105

 Gly Arg Gly Asp Met Lys Tyr Gly Ile Tyr Ala Val Glu Asn Glu
                 110                 115                 120

 His Met Asn Arg Leu Gln Ser Gln Arg Ala Met Leu Leu Gln Gly
                 125                 130                 135

 Thr Glu Ser Leu Asn Arg Ala Thr Gln Ser Ile Glu Arg Ser His
                 140                 145                 150

 Arg Ile Ala Thr Glu Thr Asp Gln Ile Gly Ser Glu Ile Ile Glu
                 155                 160                 165

 Glu Leu Gly Glu Gln Arg Asp Gln Leu Glu Arg Thr Lys Ser Arg
                 170                 175                 180

 Leu Val Asn Thr Ser Glu Asn Leu Ser Lys Ser Arg Lys Ile Leu
                 185                 190                 195

 Arg Ser Met Ser Arg Lys Val Thr Thr Asn Lys Leu Leu Leu Ser
                 200                 205                 210

 Ile Ile Ile Leu Leu Glu Leu Ala Ile Leu Gly Gly Leu Val Tyr
                 215                 220                 225

 Tyr Lys Phe Phe Arg Ser His
                 230

<210> 5719
<211> 2221
<212> DNA
<213> Homo sapien

<400> 5719
 cgcgggggcg ggcgcgcacc gggagcgcgt cggaggcgag tggaactgga 50

 tcgggtttgc tgccagcggc gtgagcttcg gccgccattt tacaacagct 100

 ccactcgcgc cggacacagg gagcagcgag cacgcgtttc ccgcaacccg 150

 ataccatcgg acaggatttc tccgcctcag cccaacgggg agatctctgg 200

 aaacatggct acagaacatg ttaatggaaa tggtactgaa gagcccatgg 250

 atactacttc tgcagttatc cattcagaaa attttcagac attgcttgat 300

 gctggtttac cacagaaagt tgctgaaaaa ctagatgaaa tttacgttgc 350

 agggctagtt gcacatagtg atttagatga aagagctatt gaagctttaa 400

 aagaattcaa tgaagacggt gcattggcag ttcttcaaca gtttaaagac 450

 agtgatctct ctcatgttca gaacaaaagt gcctttttat gtggagtcat 500

 gaagacttac aggcagagag aaaaacaagg gaccaaagta gcagattcta 550

 gtaaaggacc agatgaggca aaaattaagg cactcttgga aagaacaggc 600

 tacacacttg atgtgaccac tggacagagg aagtatggag gaccacctcc 650

 agattccgtt tattcaggtc agcagccttc tgttggcact gagatatttg 700

 tgggaaagat cccaagagat ctatttgagg atgaacttgt tccattattt 750

 gagaaagctg gacctatatg ggatcttcgt ctaatgatgg atccactcac 800

 tggtctcaat agaggttatg cgtttgtcac tttttgtaca aaagaagcag 850

 ctcaggaggc tgttaaactg tataataatc atgaaattcg ttctggaaaa 900

 catattggtg tctgcatctc agttgccaac aataggcttt ttgtgggctc 950

 tattcctaag agtaaaacca aggaacagat tcttgaagaa tttagccaag 1000

 taacagaggg tcttacagac gtcattttat accaccaacc ggatgacaag 1050

 aaaaaaaaca gaggcttttg ctttcttgaa tatgaagatc acaaaacagc 1100

 tgcccaggca aggcgtaggt taatgagtgg taaagtcaag gtctggggga 1150

 atgttggaac tgttgaatgg gctgatccta tagaagatcc tgatcctgag 1200

 gttatggcaa aggtaaaagt gctgtttgta cgcaaccttg ccaatactgt 1250

 aacagaagag attttagaaa aggcatttag tcagtttggg aaactggaac 1300

 gagtgaagaa gttaaaagat tatgcgttca ttcattttga tgagcgagat 1350

 ggtgctgtca aggctatgga agaaatgaat ggcaaagact tggagggaga 1400

 aaatattgaa attgtttttg ccaagccacc agatcagaaa aggaaagaaa 1450

 gaaaagctca gaggcaagca gcaaaaaatc aaatgtatga cgattactac 1500

 tattatggtc cacctcatat gccccctcca acaagaggtc gagggcgtgg 1550

 aggtagaggt ggttatggat atcctccaga ttattatgga tatgaagatt 1600

 attatgatta ttatggttat gattaccata actatcgtgg tggatatgaa 1650

 gatccatact atggttatga agattttcaa gttggagcta gaggaagggg 1700

 tggtagagga gcaaggggtg ctgctccatc cagaggtcgt ggggctgctc 1750

 ctccccgcgg tagagccggt tattcacaga gaggaggtcc tggatcagca 1800

 agaggcgttc gaggtgcgag aggaggtgcc caacaacaaa gaggccgcgg 1850

 gcagggaaaa ggggtcgagg ccggtcctga cctgttacaa tgaagactga 1900

 cttgctatgt gggattacac cagaagcttg cagtggagta atggtaagga 1950

 aatcaagcaa ccttaaatat gtcggctgta taggagcata ttctattgca 2000

 gaagaccttc ctatgaagat catggaatca aatacgggac attgaactaa 2050

 tacttggact ttgatatgaa tttctttaac aattttctct gcagtgcaag 2100

 ttattaaact aaagctactc tattttcaaa atgtgttcca acagaaatcc 2150

 ttcataactc ctagcatggt atcttaataa agaataaagt tcttttaaaa 2200

 atcaaaaaaa aaaaaaaaaa a 2221

<210> 5720
<211> 562
<212> PRT
<213> Homo sapien

<400> 5720
 Met Ala Thr Glu His Val Asn Gly Asn Gly Thr Glu Glu Pro Met
   1               5                  10                  15

 Asp Thr Thr Ser Ala Val Ile His Ser Glu Asn Phe Gln Thr Leu
                  20                  25                  30

 Leu Asp Ala Gly Leu Pro Gln Lys Val Ala Glu Lys Leu Asp Glu
                  35                  40                  45

 Ile Tyr Val Ala Gly Leu Val Ala His Ser Asp Leu Asp Glu Arg
                  50                  55                  60

 Ala Ile Glu Ala Leu Lys Glu Phe Asn Glu Asp Gly Ala Leu Ala
                  65                  70                  75

 Val Leu Gln Gln Phe Lys Asp Ser Asp Leu Ser His Val Gln Asn
                  80                  85                  90

 Lys Ser Ala Phe Leu Cys Gly Val Met Lys Thr Tyr Arg Gln Arg
                  95                 100                 105

 Glu Lys Gln Gly Thr Lys Val Ala Asp Ser Ser Lys Gly Pro Asp
                 110                 115                 120

 Glu Ala Lys Ile Lys Ala Leu Leu Glu Arg Thr Gly Tyr Thr Leu
                 125                 130                 135

 Asp Val Thr Thr Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro Asp
                 140                 145                 150

 Ser Val Tyr Ser Gly Gln Gln Pro Ser Val Gly Thr Glu Ile Phe
                 155                 160                 165

 Val Gly Lys Ile Pro Arg Asp Leu Phe Glu Asp Glu Leu Val Pro
                 170                 175                 180

 Leu Phe Glu Lys Ala Gly Pro Ile Trp Asp Leu Arg Leu Met Met
                 185                 190                 195

 Asp Pro Leu Thr Gly Leu Asn Arg Gly Tyr Ala Phe Val Thr Phe
                 200                 205                 210

 Cys Thr Lys Glu Ala Ala Gln Glu Ala Val Lys Leu Tyr Asn Asn
                 215                 220                 225

 His Glu Ile Arg Ser Gly Lys His Ile Gly Val Cys Ile Ser Val
                 230                 235                 240

 Ala Asn Asn Arg Leu Phe Val Gly Ser Ile Pro Lys Ser Lys Thr
                 245                 250                 255

 Lys Glu Gln Ile Leu Glu Glu Phe Ser Gln Val Thr Glu Gly Leu
                 260                 265                 270

 Thr Asp Val Ile Leu Tyr His Gln Pro Asp Asp Lys Lys Lys Asn
                 275                 280                 285

 Arg Gly Phe Cys Phe Leu Glu Tyr Glu Asp His Lys Thr Ala Ala
                 290                 295                 300

 Gln Ala Arg Arg Arg Leu Met Ser Gly Lys Val Lys Val Trp Gly
                 305                 310                 315

 Asn Val Gly Thr Val Glu Trp Ala Asp Pro Ile Glu Asp Pro Asp
                 320                 325                 330

 Pro Glu Val Met Ala Lys Val Lys Val Leu Phe Val Arg Asn Leu
                 335                 340                 345

 Ala Asn Thr Val Thr Glu Glu Ile Leu Glu Lys Ala Phe Ser Gln
                 350                 355                 360

 Phe Gly Lys Leu Glu Arg Val Lys Lys Leu Lys Asp Tyr Ala Phe
                 365                 370                 375

 Ile His Phe Asp Glu Arg Asp Gly Ala Val Lys Ala Met Glu Glu
                 380                 385                 390

 Met Asn Gly Lys Asp Leu Glu Gly Glu Asn Ile Glu Ile Val Phe
                 395                 400                 405

 Ala Lys Pro Pro Asp Gln Lys Arg Lys Glu Arg Lys Ala Gln Arg
                 410                 415                 420

 Gln Ala Ala Lys Asn Gln Met Tyr Asp Asp Tyr Tyr Tyr Tyr Gly
                 425                 430                 435

 Pro Pro His Met Pro Pro Pro Thr Arg Gly Arg Gly Arg Gly Gly
                 440                 445                 450

 Arg Gly Gly Tyr Gly Tyr Pro Pro Asp Tyr Tyr Gly Tyr Glu Asp
                 455                 460                 465

 Tyr Tyr Asp Tyr Tyr Gly Tyr Asp Tyr His Asn Tyr Arg Gly Gly
                 470                 475                 480

 Tyr Glu Asp Pro Tyr Tyr Gly Tyr Glu Asp Phe Gln Val Gly Ala
                 485                 490                 495

 Arg Gly Arg Gly Gly Arg Gly Ala Arg Gly Ala Ala Pro Ser Arg
                 500                 505                 510

 Gly Arg Gly Ala Ala Pro Pro Arg Gly Arg Ala Gly Tyr Ser Gln
                 515                 520                 525

 Arg Gly Gly Pro Gly Ser Ala Arg Gly Val Arg Gly Ala Arg Gly
                 530                 535                 540

 Gly Ala Gln Gln Gln Arg Gly Arg Gly Gln Gly Lys Gly Val Glu
                 545                 550                 555

 Ala Gly Pro Asp Leu Leu Gln
                 560

<210> 5721
<211> 661
<212> DNA
<213> Homo sapien

<400> 5721
 ccggcggtga caacggcaac atggccctga acggagctga agtcgacgac 50

 ttctcctggg agcccccgac tgaggcggag acgaaggtgc tgcaggcgcg 100

 acgggagcgg caagatcgca tctcccggct catgggcgac tatctgctgc 150

 gcggttaccg catgctgggc gagacgtgtg cggactgcgg gacgatcctc 200

 ctccaagaca aacagcggaa aatctactgc gtggcttgtc aggaactcga 250

 ctcagacgtg gataaagata atcccgctct gaatgcccag gctgccctct 300

 cccaagctcg ggagcaccag ctggcctcag cctcagagct ccccctgggc 350

 tctcgacctg cgccccagcc cccagtacct cgtccggagc actgtgaggg 400

 agctgcagca ggactcaagg cagcccaggg gccacctgct cctgctgtgc 450

 ctccaaatac agatgtcatg gcctgcacac agacagccct cttgcagaag 500

 ctgacctggg cctctgctga actgggctcc agcacctccc tggagactag 550

 catccagctg tgtggcctta tccgcgcatg tgcggaggcc ctgcgcagcc 600

 tgcagcagct acagcactaa gagaagcccc tgagaaaaac cctctagaaa 650

 aacaaaaaaa a 661

<210> 5722
<211> 199
<212> PRT
<213> Homo sapien

<400> 5722
 Met Ala Leu Asn Gly Ala Glu Val Asp Asp Phe Ser Trp Glu Pro
   1               5                  10                  15

 Pro Thr Glu Ala Glu Thr Lys Val Leu Gln Ala Arg Arg Glu Arg
                  20                  25                  30

 Gln Asp Arg Ile Ser Arg Leu Met Gly Asp Tyr Leu Leu Arg Gly
                  35                  40                  45

 Tyr Arg Met Leu Gly Glu Thr Cys Ala Asp Cys Gly Thr Ile Leu
                  50                  55                  60

 Leu Gln Asp Lys Gln Arg Lys Ile Tyr Cys Val Ala Cys Gln Glu
                  65                  70                  75

 Leu Asp Ser Asp Val Asp Lys Asp Asn Pro Ala Leu Asn Ala Gln
                  80                  85                  90

 Ala Ala Leu Ser Gln Ala Arg Glu His Gln Leu Ala Ser Ala Ser
                  95                 100                 105

 Glu Leu Pro Leu Gly Ser Arg Pro Ala Pro Gln Pro Pro Val Pro
                 110                 115                 120

 Arg Pro Glu His Cys Glu Gly Ala Ala Ala Gly Leu Lys Ala Ala
                 125                 130                 135

 Gln Gly Pro Pro Ala Pro Ala Val Pro Pro Asn Thr Asp Val Met
                 140                 145                 150

 Ala Cys Thr Gln Thr Ala Leu Leu Gln Lys Leu Thr Trp Ala Ser
                 155                 160                 165

 Ala Glu Leu Gly Ser Ser Thr Ser Leu Glu Thr Ser Ile Gln Leu
                 170                 175                 180

 Cys Gly Leu Ile Arg Ala Cys Ala Glu Ala Leu Arg Ser Leu Gln
                 185                 190                 195

 Gln Leu Gln His


<210> 5723
<211> 921
<212> DNA
<213> Homo sapien

<400> 5723
 gcggcgctcg cgccaaggga cgtgtttctg cgctcgcgtg gtcatggagg 50

 cgctgccgct gctagccgcg acaactccgg accacggccg ccaccgaagg 100

 ctgcttctgc tgccgctact gctgttcctg ctgccggctg gagctgtgca 150

 gggctgggag acagaggaga ggccccggac tcgcgaagag gagtgccact 200

 tctacgcggg tggacaagtg tacccgggag aggcatcccg ggtatcggtc 250

 gccgaccact ccctgcacct aagcaaagcg aagatttcca agccagcgcc 300

 ctactgggaa ggaacagctg tgatcgatgg agaatttaag gagctgaagt 350

 taactgatta tcgtgggaaa tacttggttt tcttcttcta cccacttgat 400

 ttcacatttg tgtgtccaac tgaaattatc gcttttggcg acagacttga 450

 agaattcaga tctataaata ctgaagtggt agcatgctct gttgattcac 500

 agtttaccca tttggcctgg attaataccc ctcgaagaca aggaggactt 550

 gggccaataa ggattccact tctttcagat ttgacccatc agatctcaaa 600

 ggactatggt gtatacctag aggactcagg ccacactctt agaggtctct 650

 tcattattga tgacaaagga atcctaagac aaattactct gaatgatctt 700

 cctgtgggta gatcagtgga tgagacacta cgtttggttc aagcattcca 750

 gtacactgac aaacacggag aagtctgccc tgctggctgg aaacctggta 800

 gtgaaacaat aatcccagat ccagctggaa agctgaagta tttcgataaa 850

 ctgaattgag aaatacttct tcaagttatg atgcttgaaa gttctcaata 900

 aagttcacgg tttcattacc a 921

<210> 5724
<211> 271
<212> PRT
<213> Homo sapien

<400> 5724
 Met Glu Ala Leu Pro Leu Leu Ala Ala Thr Thr Pro Asp His Gly
   1               5                  10                  15

 Arg His Arg Arg Leu Leu Leu Leu Pro Leu Leu Leu Phe Leu Leu
                  20                  25                  30

 Pro Ala Gly Ala Val Gln Gly Trp Glu Thr Glu Glu Arg Pro Arg
                  35                  40                  45

 Thr Arg Glu Glu Glu Cys His Phe Tyr Ala Gly Gly Gln Val Tyr
                  50                  55                  60

 Pro Gly Glu Ala Ser Arg Val Ser Val Ala Asp His Ser Leu His
                  65                  70                  75

 Leu Ser Lys Ala Lys Ile Ser Lys Pro Ala Pro Tyr Trp Glu Gly
                  80                  85                  90

 Thr Ala Val Ile Asp Gly Glu Phe Lys Glu Leu Lys Leu Thr Asp
                  95                 100                 105

 Tyr Arg Gly Lys Tyr Leu Val Phe Phe Phe Tyr Pro Leu Asp Phe
                 110                 115                 120

 Thr Phe Val Cys Pro Thr Glu Ile Ile Ala Phe Gly Asp Arg Leu
                 125                 130                 135

 Glu Glu Phe Arg Ser Ile Asn Thr Glu Val Val Ala Cys Ser Val
                 140                 145                 150

 Asp Ser Gln Phe Thr His Leu Ala Trp Ile Asn Thr Pro Arg Arg
                 155                 160                 165

 Gln Gly Gly Leu Gly Pro Ile Arg Ile Pro Leu Leu Ser Asp Leu
                 170                 175                 180

 Thr His Gln Ile Ser Lys Asp Tyr Gly Val Tyr Leu Glu Asp Ser
                 185                 190                 195

 Gly His Thr Leu Arg Gly Leu Phe Ile Ile Asp Asp Lys Gly Ile
                 200                 205                 210

 Leu Arg Gln Ile Thr Leu Asn Asp Leu Pro Val Gly Arg Ser Val
                 215                 220                 225

 Asp Glu Thr Leu Arg Leu Val Gln Ala Phe Gln Tyr Thr Asp Lys
                 230                 235                 240

 His Gly Glu Val Cys Pro Ala Gly Trp Lys Pro Gly Ser Glu Thr
                 245                 250                 255

 Ile Ile Pro Asp Pro Ala Gly Lys Leu Lys Tyr Phe Asp Lys Leu
                 260                 265                 270

 Asn


<210> 5725
<211> 1863
<212> DNA
<213> Homo sapien

<400> 5725
 gttccaaggt ttgcggcccg gtctcggaga agaggggaga gtggagggcc 50

 gctgaataag cttccaaaat gatgcccaca ccagttatcc tattgaaaga 100

 ggggactgat agctcccaag gcatccccca gcttgtgagt aacatcagtg 150

 cctgccaggt gattgctgag gctgtaagaa ctaccctggg tccccgtggc 200

 atggacaagc ttattgtaga tggcagaggc aaagcaacaa tttctaatga 250

 tggggccaca attctgaaac ttcttgatgt tgtccatcct gcagcaaaga 300

 ctttggtaga cattgccaaa tcccaagatg ctgaggtggg tgatggcacc 350

 acctcagtga ccttgctggc tgcagagttt ctgaagcagg tgaaacccta 400

 tgtggaggaa ggtttacacc cccagatcat cattcgagct ttccgcacag 450

 ccacccagct ggcagttaac aagatcaaag agattgctgt gaccgtgaag 500

 aaggcagata aagtggagca gaggaagctg ctggaaaagt gtgccatgac 550

 cgctctgagc tccaagctga tctcccagca gaaagctttc tttgctaaga 600

 tggtggtgga tgcagtgatg atgctcgatg atttgctgca gcttaaaatg 650

 attggaatca agaaggtaca gggtggagcc ctcgaggatt ctcagctggt 700

 agctggtgtt gcattcaaga agactttctc ttacgctggg tttgaaatgc 750

 aacccaaaaa gtaccacaat cccaagattg cccttttgaa tgtcgagctc 800

 gagttgaaag ctgagaaaga caatgctgag ataagagtcc acacagttga 850

 ggattatcag gcaattgttg atgctgagtg gaacattctc tatgacaagt 900

 tagagaagat ccatcattct ggagccaaag ttgtcttgtc caaactcccc 950

 attggggatg tggccaccca gtactttgct gacagggaca tgttctgtgc 1000

 tggccgagta cctgaggagg atctgaagag gacaatgatg gcctgtggag 1050

 gctcaatcca gaccagtgtg aatgctctgt cagcagatgt gctgggtcga 1100

 tgccaggtgt ttgaagagac ccagattgga ggcgagaggt acaatttttt 1150

 tactggctgc cccaaggcca agacatgcac cttcattctc cgtggcggcg 1200

 ccgagcagtt tatggaggag acagagcggt ccctgcatga tgccatcatg 1250

 atcgtcagga gggccatcaa gaatgattca gtggtggctg gtggcggggc 1300

 cattgagatg gaactctcca agtacctgcg ggattactca aggactattc 1350

 caggaaaaca gcagctgttg attggggctt atgccaaggc cttggagatt 1400

 atcccacgcc agctgtgtga caatgctggc tttgatgcca caaacattct 1450

 caacaagctg cgggctcggc atgcccaggg gggtacatgg tatggagtag 1500

 acatcaacaa cgaggacatt gctgacaact ttgaagcttt cgtgtgggag 1550

 ccagctatgg tgcggatcaa tgcgctgaca gcagcctctg aggctgcgtg 1600

 cctgatcgtg tctgtagatg aaaccatcaa gaacccccgc tcgactgtgg 1650

 atgctcccac agcagcaggc cggggccgtg gtcgtggccg cccccactga 1700

 gaggcacccc acccatcaca tggctggctg gctgctgggt gcacttaccc 1750

 tccttggctt ggttacttca ttttacaagg aaggggtagt aattggccca 1800

 ctctcttctt actggaggct atttaaataa aatgtaagac ttcaaaaaaa 1850

 aaaaaaaaaa aaa 1863

<210> 5726
<211> 543
<212> PRT
<213> Homo sapien

<400> 5726
 Met Met Pro Thr Pro Val Ile Leu Leu Lys Glu Gly Thr Asp Ser
   1               5                  10                  15

 Ser Gln Gly Ile Pro Gln Leu Val Ser Asn Ile Ser Ala Cys Gln
                  20                  25                  30

 Val Ile Ala Glu Ala Val Arg Thr Thr Leu Gly Pro Arg Gly Met
                  35                  40                  45

 Asp Lys Leu Ile Val Asp Gly Arg Gly Lys Ala Thr Ile Ser Asn
                  50                  55                  60

 Asp Gly Ala Thr Ile Leu Lys Leu Leu Asp Val Val His Pro Ala
                  65                  70                  75

 Ala Lys Thr Leu Val Asp Ile Ala Lys Ser Gln Asp Ala Glu Val
                  80                  85                  90

 Gly Asp Gly Thr Thr Ser Val Thr Leu Leu Ala Ala Glu Phe Leu
                  95                 100                 105

 Lys Gln Val Lys Pro Tyr Val Glu Glu Gly Leu His Pro Gln Ile
                 110                 115                 120

 Ile Ile Arg Ala Phe Arg Thr Ala Thr Gln Leu Ala Val Asn Lys
                 125                 130                 135

 Ile Lys Glu Ile Ala Val Thr Val Lys Lys Ala Asp Lys Val Glu
                 140                 145                 150

 Gln Arg Lys Leu Leu Glu Lys Cys Ala Met Thr Ala Leu Ser Ser
                 155                 160                 165

 Lys Leu Ile Ser Gln Gln Lys Ala Phe Phe Ala Lys Met Val Val
                 170                 175                 180

 Asp Ala Val Met Met Leu Asp Asp Leu Leu Gln Leu Lys Met Ile
                 185                 190                 195

 Gly Ile Lys Lys Val Gln Gly Gly Ala Leu Glu Asp Ser Gln Leu
                 200                 205                 210

 Val Ala Gly Val Ala Phe Lys Lys Thr Phe Ser Tyr Ala Gly Phe
                 215                 220                 225

 Glu Met Gln Pro Lys Lys Tyr His Asn Pro Lys Ile Ala Leu Leu
                 230                 235                 240

 Asn Val Glu Leu Glu Leu Lys Ala Glu Lys Asp Asn Ala Glu Ile
                 245                 250                 255

 Arg Val His Thr Val Glu Asp Tyr Gln Ala Ile Val Asp Ala Glu
                 260                 265                 270

 Trp Asn Ile Leu Tyr Asp Lys Leu Glu Lys Ile His His Ser Gly
                 275                 280                 285

 Ala Lys Val Val Leu Ser Lys Leu Pro Ile Gly Asp Val Ala Thr
                 290                 295                 300

 Gln Tyr Phe Ala Asp Arg Asp Met Phe Cys Ala Gly Arg Val Pro
                 305                 310                 315

 Glu Glu Asp Leu Lys Arg Thr Met Met Ala Cys Gly Gly Ser Ile
                 320                 325                 330

 Gln Thr Ser Val Asn Ala Leu Ser Ala Asp Val Leu Gly Arg Cys
                 335                 340                 345

 Gln Val Phe Glu Glu Thr Gln Ile Gly Gly Glu Arg Tyr Asn Phe
                 350                 355                 360

 Phe Thr Gly Cys Pro Lys Ala Lys Thr Cys Thr Phe Ile Leu Arg
                 365                 370                 375

 Gly Gly Ala Glu Gln Phe Met Glu Glu Thr Glu Arg Ser Leu His
                 380                 385                 390

 Asp Ala Ile Met Ile Val Arg Arg Ala Ile Lys Asn Asp Ser Val
                 395                 400                 405

 Val Ala Gly Gly Gly Ala Ile Glu Met Glu Leu Ser Lys Tyr Leu
                 410                 415                 420

 Arg Asp Tyr Ser Arg Thr Ile Pro Gly Lys Gln Gln Leu Leu Ile
                 425                 430                 435

 Gly Ala Tyr Ala Lys Ala Leu Glu Ile Ile Pro Arg Gln Leu Cys
                 440                 445                 450

 Asp Asn Ala Gly Phe Asp Ala Thr Asn Ile Leu Asn Lys Leu Arg
                 455                 460                 465

 Ala Arg His Ala Gln Gly Gly Thr Trp Tyr Gly Val Asp Ile Asn
                 470                 475                 480

 Asn Glu Asp Ile Ala Asp Asn Phe Glu Ala Phe Val Trp Glu Pro
                 485                 490                 495

 Ala Met Val Arg Ile Asn Ala Leu Thr Ala Ala Ser Glu Ala Ala
                 500                 505                 510

 Cys Leu Ile Val Ser Val Asp Glu Thr Ile Lys Asn Pro Arg Ser
                 515                 520                 525

 Thr Val Asp Ala Pro Thr Ala Ala Gly Arg Gly Arg Gly Arg Gly
                 530                 535                 540

 Arg Pro His


<210> 5727
<211> 1983
<212> DNA
<213> Homo sapien

<400> 5727
 gaattgaacc acccattttc ctttcttagc caaatcacca aaatgtccag 50

 ttagaacaag aatttagcat tctgcaaaag aagttaacag ctgagataac 100

 gaggaaatat tctgaaatgg atcccaaata tttcatctta attttgtttt 150

 gtggacacct gaacaataca tttttttcaa agacagagac aattacaaca 200

 gagaagcagt cacagcctac cttattcaca tcatcaatgt cacaggtatt 250

 ggctaattct caaaacacaa cagggaatcc tttgggtcaa ccaacacaat 300

 tcagcgacac tttttctgga caatcaatat cacctgccaa agtcactgct 350

 ggacaaccaa caccagctgt ctatacctct tctgaaaaac cagaagcaca 400

 tacttctgct ggacaaccac ttgcctacaa caccaaacaa ccaacaccaa 450

 tagccaacac ctcctcccag caagccgtgt tcacctctgc cagacaacta 500

 ccatctgccc gtacttctac cacacaacca ccaaagtcat ttgtctatac 550

 ttttactcaa caatcatcat ctgtccagat cccttctaga aaacaaataa 600

 ctgttcataa tccatccaca caaccaacat caactgtcaa aaattcacct 650

 aggagtacac caggatttat cttagatact accagtaaca aacaaacccc 700

 acaaaaaaac aattataatt caatagctgc catactaatt ggtgtacttc 750

 tgacttctat gttggtagct ataatcatca ttgtactttg gaaatgctta 800

 aggaaaccag ttttaaatga tcaaaattgg gcaggtagat ctccatttgc 850

 tgatggagaa acccctgaca tttgtatgga taacatcaga gaaaatgaaa 900

 tatccacaaa acgtacatca atcatttcac ttacaccctg gaaaccaagc 950

 aaaagcacac ttttagcaga tgacttagaa attaagttgt ttgaatcaag 1000

 tgaaaacatt gaagactcca acaaccccaa aacagagaaa ataaaagatc 1050

 aagtaaatgg tacatcagaa gatagtgctg atggttcaac agttggaact 1100

 gctgtttctt cttcagatga tgcaggtctg cctccaccac ctccccttct 1150

 ggatttggaa ggacaggaaa gtaaccaatc tgacaaaccc acaatgacaa 1200

 ttgtatctcc tcttccaaat gattctacta gtctccctcc atctctggac 1250

 tgtctcaatc aagactgtgg agatcataaa tctgagataa tacaatcatt 1300

 tccaccgctt gactcactta acttgcccct gccaccagta gattttatga 1350

 aaaaccaaga agattccaac cttgagatcc agtgtcagga gttctctatt 1400

 cctcccaact ctgatcaaga tcttaatgaa tccctgccac ctccacctgc 1450

 agaactgtta taaatattac aacttgcttt ttagctgatc ttccatcctc 1500

 aaatgactct tttttcttta tatgttaaca tatataaaat ggcaactgat 1550

 agtcaatttt gatttttatt caggaactat ctgaaatctg ctcagagcct 1600

 atgtgcatag atgaaacttt tttttaaaaa aagttattta acagtaatct 1650

 atttactaat tatagtacct atctttaaag tatagtacat tttacatatg 1700

 taaatggtat gtttcaataa tttaagaact ctgaaacaat ctacatatac 1750

 ttattaccca gtacagtttt ttttcccctg aaaagctgtg tataaaatta 1800

 tggtgaataa acttttatgt ttccatttca aagaccaggg tggagaggaa 1850

 taagagacta agtatatgct tcaagtttta aattaatacc tcaagtatta 1900

 aataaatatt ccaagtttgt gggaatggga gattaaaatg catgtttgag 1950

 agtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 1983

<210> 5728
<211> 448
<212> PRT
<213> Homo sapien

<400> 5728
 Met Asp Pro Lys Tyr Phe Ile Leu Ile Leu Phe Cys Gly His Leu
   1               5                  10                  15

 Asn Asn Thr Phe Phe Ser Lys Thr Glu Thr Ile Thr Thr Glu Lys
                  20                  25                  30

 Gln Ser Gln Pro Thr Leu Phe Thr Ser Ser Met Ser Gln Val Leu
                  35                  40                  45

 Ala Asn Ser Gln Asn Thr Thr Gly Asn Pro Leu Gly Gln Pro Thr
                  50                  55                  60

 Gln Phe Ser Asp Thr Phe Ser Gly Gln Ser Ile Ser Pro Ala Lys
                  65                  70                  75

 Val Thr Ala Gly Gln Pro Thr Pro Ala Val Tyr Thr Ser Ser Glu
                  80                  85                  90

 Lys Pro Glu Ala His Thr Ser Ala Gly Gln Pro Leu Ala Tyr Asn
                  95                 100                 105

 Thr Lys Gln Pro Thr Pro Ile Ala Asn Thr Ser Ser Gln Gln Ala
                 110                 115                 120

 Val Phe Thr Ser Ala Arg Gln Leu Pro Ser Ala Arg Thr Ser Thr
                 125                 130                 135

 Thr Gln Pro Pro Lys Ser Phe Val Tyr Thr Phe Thr Gln Gln Ser
                 140                 145                 150

 Ser Ser Val Gln Ile Pro Ser Arg Lys Gln Ile Thr Val His Asn
                 155                 160                 165

 Pro Ser Thr Gln Pro Thr Ser Thr Val Lys Asn Ser Pro Arg Ser
                 170                 175                 180

 Thr Pro Gly Phe Ile Leu Asp Thr Thr Ser Asn Lys Gln Thr Pro
                 185                 190                 195

 Gln Lys Asn Asn Tyr Asn Ser Ile Ala Ala Ile Leu Ile Gly Val
                 200                 205                 210

 Leu Leu Thr Ser Met Leu Val Ala Ile Ile Ile Ile Val Leu Trp
                 215                 220                 225

 Lys Cys Leu Arg Lys Pro Val Leu Asn Asp Gln Asn Trp Ala Gly
                 230                 235                 240

 Arg Ser Pro Phe Ala Asp Gly Glu Thr Pro Asp Ile Cys Met Asp
                 245                 250                 255

 Asn Ile Arg Glu Asn Glu Ile Ser Thr Lys Arg Thr Ser Ile Ile
                 260                 265                 270

 Ser Leu Thr Pro Trp Lys Pro Ser Lys Ser Thr Leu Leu Ala Asp
                 275                 280                 285

 Asp Leu Glu Ile Lys Leu Phe Glu Ser Ser Glu Asn Ile Glu Asp
                 290                 295                 300

 Ser Asn Asn Pro Lys Thr Glu Lys Ile Lys Asp Gln Val Asn Gly
                 305                 310                 315

 Thr Ser Glu Asp Ser Ala Asp Gly Ser Thr Val Gly Thr Ala Val
                 320                 325                 330

 Ser Ser Ser Asp Asp Ala Gly Leu Pro Pro Pro Pro Pro Leu Leu
                 335                 340                 345

 Asp Leu Glu Gly Gln Glu Ser Asn Gln Ser Asp Lys Pro Thr Met
                 350                 355                 360

 Thr Ile Val Ser Pro Leu Pro Asn Asp Ser Thr Ser Leu Pro Pro
                 365                 370                 375

 Ser Leu Asp Cys Leu Asn Gln Asp Cys Gly Asp His Lys Ser Glu
                 380                 385                 390

 Ile Ile Gln Ser Phe Pro Pro Leu Asp Ser Leu Asn Leu Pro Leu
                 395                 400                 405

 Pro Pro Val Asp Phe Met Lys Asn Gln Glu Asp Ser Asn Leu Glu
                 410                 415                 420

 Ile Gln Cys Gln Glu Phe Ser Ile Pro Pro Asn Ser Asp Gln Asp
                 425                 430                 435

 Leu Asn Glu Ser Leu Pro Pro Pro Pro Ala Glu Leu Leu
                 440                 445

<210> 5729
<211> 1107
<212> DNA
<213> Homo sapien

<400> 5729
 acacagaaga gactccaatc gacaagaagc tggaaaagaa tgatgttgtc 50

 cttaaacaac ctacagaata tcatctataa cccggtaatc ccgtttgttg 100

 gcaccattcc tgatcagctg gatcctggaa ctttgattgt gatacgtggg 150

 catgttccta gtgacgcaga cagattccag gtggatctgc agaatggcag 200

 cagcatgaaa cctcgagccg atgtggcctt tcatttcaat cctcgtttca 250

 aaagggccgg ctgcattgtt tgcaatactt tgataaatga aaaatgggga 300

 cgggaagaga tcacctatga cacgcctttc caaaaagaga aaaagtcttt 350

 tgagatcgtg attatggtgc tgaaggccaa attccaggtg gctgtaaatg 400

 gaaaacatac tctgctctat ggccacagga tcggcccaga gaaaatagac 450

 actctgggca tttatggcaa agtgaatatt cactcaattg gttttagctt 500

 cagctcggac ttacaaagta cccaagcatc tagtctggaa ctgacagaga 550

 taagtagaga aaatgttcca aagtctggca cgccccagct taggctgcca 600

 ttcgctgcaa ggttgaacac ccccatgggc cctggacgaa ctgtcgtcgt 650

 taaaggagaa gtgaatgcaa atgccaaaag ctttaatgtt gacctactag 700

 caggaaaatc aaaggatatt gctctacact tgaacccacg cctgaatatt 750

 aaagcatttg taagaaattc ttttcttcag gagtcctggg gagaagaaga 800

 gagaaatatt acctctttcc catttagtcc tgggatgtac tttgagatga 850

 taatttattg tgatgttaga gaattcaagg ttgcagtaaa tggcgtacac 900

 agcctggagt acaaacacag atttaaagag ctcagcagta ttgacacgct 950

 ggaaattaat ggagacatcc acttactgga agtaaggagc tggtagccta 1000

 cctacacagc tgctacaaaa accaaaatac agaatggctt ctgtgatact 1050

 ggccttgctg aaacgcatct cactgtcatt ctattgttta tattgttaaa 1100

 atgacct 1107

<210> 5730
<211> 318
<212> PRT
<213> Homo sapien

<400> 5730
 Met Met Leu Ser Leu Asn Asn Leu Gln Asn Ile Ile Tyr Asn Pro
   1               5                  10                  15

 Val Ile Pro Phe Val Gly Thr Ile Pro Asp Gln Leu Asp Pro Gly
                  20                  25                  30

 Thr Leu Ile Val Ile Arg Gly His Val Pro Ser Asp Ala Asp Arg
                  35                  40                  45

 Phe Gln Val Asp Leu Gln Asn Gly Ser Ser Met Lys Pro Arg Ala
                  50                  55                  60

 Asp Val Ala Phe His Phe Asn Pro Arg Phe Lys Arg Ala Gly Cys
                  65                  70                  75

 Ile Val Cys Asn Thr Leu Ile Asn Glu Lys Trp Gly Arg Glu Glu
                  80                  85                  90

 Ile Thr Tyr Asp Thr Pro Phe Gln Lys Glu Lys Lys Ser Phe Glu
                  95                 100                 105

 Ile Val Ile Met Val Leu Lys Ala Lys Phe Gln Val Ala Val Asn
                 110                 115                 120

 Gly Lys His Thr Leu Leu Tyr Gly His Arg Ile Gly Pro Glu Lys
                 125                 130                 135

 Ile Asp Thr Leu Gly Ile Tyr Gly Lys Val Asn Ile His Ser Ile
                 140                 145                 150

 Gly Phe Ser Phe Ser Ser Asp Leu Gln Ser Thr Gln Ala Ser Ser
                 155                 160                 165

 Leu Glu Leu Thr Glu Ile Ser Arg Glu Asn Val Pro Lys Ser Gly
                 170                 175                 180

 Thr Pro Gln Leu Arg Leu Pro Phe Ala Ala Arg Leu Asn Thr Pro
                 185                 190                 195

 Met Gly Pro Gly Arg Thr Val Val Val Lys Gly Glu Val Asn Ala
                 200                 205                 210

 Asn Ala Lys Ser Phe Asn Val Asp Leu Leu Ala Gly Lys Ser Lys
                 215                 220                 225

 Asp Ile Ala Leu His Leu Asn Pro Arg Leu Asn Ile Lys Ala Phe
                 230                 235                 240

 Val Arg Asn Ser Phe Leu Gln Glu Ser Trp Gly Glu Glu Glu Arg
                 245                 250                 255

 Asn Ile Thr Ser Phe Pro Phe Ser Pro Gly Met Tyr Phe Glu Met
                 260                 265                 270

 Ile Ile Tyr Cys Asp Val Arg Glu Phe Lys Val Ala Val Asn Gly
                 275                 280                 285

 Val His Ser Leu Glu Tyr Lys His Arg Phe Lys Glu Leu Ser Ser
                 290                 295                 300

 Ile Asp Thr Leu Glu Ile Asn Gly Asp Ile His Leu Leu Glu Val
                 305                 310                 315

 Arg Ser Trp


<210> 5731
<211> 2856
<212> DNA
<213> Homo sapien

<400> 5731
 tagtcgcggg tccccgagtg agcacgccag ggagcaggag accaaacgac 50

 gggggtcgga gtcagagtcg cagtgggagt ccccggaccg gagcacgagc 100

 ctgagcggga gagcgccgct cgcacgcccg tcgccacccg cgtacccggc 150

 gcagccagag ccaccagcgc agcgctgcca tggagcccag cagcaagaag 200

 ctgacgggtc gcctcatgct ggctgtggga ggagcagtgc ttggctccct 250

 gcagtttggc tacaacactg gagtcatcaa tgccccccag aaggtgatcg 300

 aggagttcta caaccagaca tgggtccacc gctatgggga gagcatcctg 350

 cccaccacgc tcaccacgct ctggtccctc tcagtggcca tcttttctgt 400

 tgggggcatg attggctcct tctctgtggg ccttttcgtt aaccgctttg 450

 gccggcggaa ttcaatgctg atgatgaacc tgctggcctt cgtgtccgcc 500

 gtgctcatgg gcttctcgaa actgggcaag tcctttgaga tgctgatcct 550

 gggccgcttc atcatcggtg tgtactgcgg cctgaccaca ggcttcgtgc 600

 ccatgtatgt gggtgaagtg tcacccacag cctttcgtgg ggccctgggc 650

 accctgcacc agctgggcat cgtcgtcggc atcctcatcg cccaggtgtt 700

 cggcctggac tccatcatgg gcaacaagga cctgtggccc ctgctgctga 750

 gcatcatctt catcccggcc ctgctgcagt gcatcgtgct gcccttctgc 800

 cccgagagtc cccgcttcct gctcatcaac cgcaacgagg agaaccgggc 850

 caagagtgtg ctaaagaagc tgcgcgggac agctgacgtg acccatgacc 900

 tgcaggagat gaaggaagag agtcggcaga tgatgcggga gaagaaggtc 950

 accatcctgg agctgttccg ctcccccgcc taccgccagc ccatcctcat 1000

 cgctgtggtg ctgcagctgt cccagcagct gtctggcatc aacgctgtct 1050

 tctattactc cacgagcatc ttcgagaagg cgggggtgca gcagcctgtg 1100

 tatgccacca ttggctccgg tatcgtcaac acggccttca ctgtcgtgtc 1150

 gctgtttgtg gtggagcgag caggccggcg gaccctgcac ctcataggcc 1200

 tcgctggcat ggcgggttgt gccatactca tgaccatcgc gctagcactg 1250

 ctggagcagc taccctggat gtcctatctg agcatcgtgg ccatctttgg 1300

 ctttgtggcc ttctttgaag tgggtcctgg ccccatccca tggttcatcg 1350

 tggctgaact cttcagccag ggtccacgtc cagctgccat tgccgttgca 1400

 ggcttctcca actggacctc aaatttcatt gtgggcatgt gcttccagta 1450

 tgtggagcaa ctgtgtggtc cctacgtctt catcatcttc actgtgctcc 1500

 tggttctgtt cttcatcttc acctacttca aagttcctga gactaaaggc 1550

 cggaccttcg atgagatcgc ttccggcttc cggcaggggg gagccagcca 1600

 aagtgataag acacccgagg agctgttcca tcccctgggg gctgattccc 1650

 aagtgtgagt cgccccagat caccagcccg gcctgctccc agcagcccta 1700

 aggatctctc aggagcacag gcagctggat gagacttcca aacctgacag 1750

 atgtcagccg agccgggcct ggggctcctt tctccagcca gcaatgatgt 1800

 ccagaagaat attcaggact taacggctcc aggattttaa caaaagcaag 1850

 actgttgctc aaatctattc agacaagcaa caggttttat aattttttta 1900

 ttactgattt tgttattttt atatcagcct gagtctcctg tgcccacatc 1950

 ccaggcttca ccctgaatgg ttccatgcct gagggtggag actaagccct 2000

 gtcgagacac ttgccttctt cacccagcta atctgtaggg ctggacctat 2050

 gtcctaagga cacactaatc gaactatgaa ctacaaagct tctatcccag 2100

 gaggtggcta tggccacccg ttctgctggc ctggatctcc ccactctagg 2150

 ggtcaggctc cattaggatt tgccccttcc catctcttcc tacccaacca 2200

 ctcaaattaa tctttcttta cctgagacca gttgggagca ctggagtgca 2250

 gggaggagag gggaagggcc agtctgggct gccgggttct agtctccttt 2300

 gcactgaggg ccacactatt accatgagaa gagggcctgt gggagcctgc 2350

 aaactcactg ctcaagaaga catggagact cctgccctgt tgtgtataga 2400

 tgcaagatat ttatatatat ttttggttgt caatattaaa tacagacact 2450

 aagttatagt atatctggac aagccaactt gtaaatacac cacctcactc 2500

 ctgttactta cctaaacaga tataaatggc tggtttttag aaacatggtt 2550

 ttgaaatgct tgtggattga gggtaggagg tttggatggg agtgagacag 2600

 aagtaagtgg ggttgcaacc actgcaacgg cttagacttc gactcaggat 2650

 ccagtccctt acacgtacct ctcatcagtg tcctcttgct caaaaatctg 2700

 tttgatccct gttacccaga gaatatatac attctttatc ttgacattca 2750

 aggcatttct atcacatatt tgatagttgg tgttcaaaaa aacactagtt 2800

 ttgtgccagc cgtgatgctc aggcttgaaa tcgcattatt ttgaatgtga 2850

 agggaa 2856

<210> 5732
<211> 492
<212> PRT
<213> Homo sapien

<400> 5732
 Met Glu Pro Ser Ser Lys Lys Leu Thr Gly Arg Leu Met Leu Ala
   1               5                  10                  15

 Val Gly Gly Ala Val Leu Gly Ser Leu Gln Phe Gly Tyr Asn Thr
                  20                  25                  30

 Gly Val Ile Asn Ala Pro Gln Lys Val Ile Glu Glu Phe Tyr Asn
                  35                  40                  45

 Gln Thr Trp Val His Arg Tyr Gly Glu Ser Ile Leu Pro Thr Thr
                  50                  55                  60

 Leu Thr Thr Leu Trp Ser Leu Ser Val Ala Ile Phe Ser Val Gly
                  65                  70                  75

 Gly Met Ile Gly Ser Phe Ser Val Gly Leu Phe Val Asn Arg Phe
                  80                  85                  90

 Gly Arg Arg Asn Ser Met Leu Met Met Asn Leu Leu Ala Phe Val
                  95                 100                 105

 Ser Ala Val Leu Met Gly Phe Ser Lys Leu Gly Lys Ser Phe Glu
                 110                 115                 120

 Met Leu Ile Leu Gly Arg Phe Ile Ile Gly Val Tyr Cys Gly Leu
                 125                 130                 135

 Thr Thr Gly Phe Val Pro Met Tyr Val Gly Glu Val Ser Pro Thr
                 140                 145                 150

 Ala Phe Arg Gly Ala Leu Gly Thr Leu His Gln Leu Gly Ile Val
                 155                 160                 165

 Val Gly Ile Leu Ile Ala Gln Val Phe Gly Leu Asp Ser Ile Met
                 170                 175                 180

 Gly Asn Lys Asp Leu Trp Pro Leu Leu Leu Ser Ile Ile Phe Ile
                 185                 190                 195

 Pro Ala Leu Leu Gln Cys Ile Val Leu Pro Phe Cys Pro Glu Ser
                 200                 205                 210

 Pro Arg Phe Leu Leu Ile Asn Arg Asn Glu Glu Asn Arg Ala Lys
                 215                 220                 225

 Ser Val Leu Lys Lys Leu Arg Gly Thr Ala Asp Val Thr His Asp
                 230                 235                 240

 Leu Gln Glu Met Lys Glu Glu Ser Arg Gln Met Met Arg Glu Lys
                 245                 250                 255

 Lys Val Thr Ile Leu Glu Leu Phe Arg Ser Pro Ala Tyr Arg Gln
                 260                 265                 270

 Pro Ile Leu Ile Ala Val Val Leu Gln Leu Ser Gln Gln Leu Ser
                 275                 280                 285

 Gly Ile Asn Ala Val Phe Tyr Tyr Ser Thr Ser Ile Phe Glu Lys
                 290                 295                 300

 Ala Gly Val Gln Gln Pro Val Tyr Ala Thr Ile Gly Ser Gly Ile
                 305                 310                 315

 Val Asn Thr Ala Phe Thr Val Val Ser Leu Phe Val Val Glu Arg
                 320                 325                 330

 Ala Gly Arg Arg Thr Leu His Leu Ile Gly Leu Ala Gly Met Ala
                 335                 340                 345

 Gly Cys Ala Ile Leu Met Thr Ile Ala Leu Ala Leu Leu Glu Gln
                 350                 355                 360

 Leu Pro Trp Met Ser Tyr Leu Ser Ile Val Ala Ile Phe Gly Phe
                 365                 370                 375

 Val Ala Phe Phe Glu Val Gly Pro Gly Pro Ile Pro Trp Phe Ile
                 380                 385                 390

 Val Ala Glu Leu Phe Ser Gln Gly Pro Arg Pro Ala Ala Ile Ala
                 395                 400                 405

 Val Ala Gly Phe Ser Asn Trp Thr Ser Asn Phe Ile Val Gly Met
                 410                 415                 420

 Cys Phe Gln Tyr Val Glu Gln Leu Cys Gly Pro Tyr Val Phe Ile
                 425                 430                 435

 Ile Phe Thr Val Leu Leu Val Leu Phe Phe Ile Phe Thr Tyr Phe
                 440                 445                 450

 Lys Val Pro Glu Thr Lys Gly Arg Thr Phe Asp Glu Ile Ala Ser
                 455                 460                 465

 Gly Phe Arg Gln Gly Gly Ala Ser Gln Ser Asp Lys Thr Pro Glu
                 470                 475                 480

 Glu Leu Phe His Pro Leu Gly Ala Asp Ser Gln Val
                 485                 490

<210> 5733
<211> 6835
<212> DNA
<213> Homo sapien

<400> 5733
 cggcggcggc tgcggcttag tcggtggcgg ccggcggcgg ctgcgggctg 50

 agcggcgagt ttccgattta aagctgagct gcgaggaaaa tggcggcggg 100

 aggatcaaaa tacttgctgg atggtggact cagagaccaa taaaaataaa 150

 ctgcttgaac atcctttgac tggttagcca gttgctgatg tatattcaag 200

 atgagtggat taggagaaaa cttggatcca ctggccagtg attcacgaaa 250

 acgcaaattg ccatgtgata ctccaggaca aggtcttacc tgcagtggtg 300

 aaaaacggag acgggagcag gaaagtaaat atattgaaga attggctgag 350

 ctgatatctg ccaatcttag tgatattgac aatttcaatg tcaaaccaga 400

 taaatgtgcg attttaaagg aaacagtaag acagatacgt caaataaaag 450

 agcaaggaaa aactatttcc aatgatgatg atgttcaaaa agccgatgta 500

 tcttctacag ggcagggagt tattgataaa gactccttag gaccgctttt 550

 acttcaggca ttggatggtt tcctatttgt ggtgaatcga gacggaaaca 600

 ttgtatttgt atcagaaaat gtcacacaat acctgcaata taagcaagag 650

 gacctggtta acacaagtgt ttacaatatc ttacatgaag aagacagaaa 700

 ggattttctt aagaatttac caaaatctac agttaatgga gtttcctgga 750

 caaatgagac ccaaagacaa aaaagccata catttaattg ccgtatgttg 800

 atgaaaacac cacatgatat tctggaagac ataaacgcca gtcctgaaat 850

 gcgccagaga tatgaaacaa tgcagtgctt tgccctgtct cagccacgag 900

 ctatgatgga ggaaggggaa gatttgcaat cttgtatgat ctgtgtggca 950

 cgccgcatta ctacaggaga aagaacattt ccatcaaacc ctgagagctt 1000

 tattaccaga catgatcttt caggaaaggt tgtcaatata gatacaaatt 1050

 cactgagatc ctccatgagg cctggctttg aagatataat ccgaaggtgt 1100

 attcagagat tttttagtct aaatgatggg cagtcatggt cccagaaacg 1150

 tcactatcaa gaagcttatc ttaatggcca tgcagaaacc ccagtatatc 1200

 gattctcgtt ggctgatgga actatagtga ctgcacagac aaaaagcaaa 1250

 ctcttccgaa atcctgtaac aaatgatcga catggctttg tctcaaccca 1300

 cttccttcag agagaacaga atggatatag accaaaccca aatcctgttg 1350

 gacaagggat tagaccacct atggctggat gcaacagttc ggtaggcggc 1400

 atgagtatgt cgccaaacca aggcttacag atgccgagca gcagggccta 1450

 tggcttggca gaccctagca ccacagggca gatgagtgga gctaggtatg 1500

 ggggttccag taacatagct tcattgaccc ctgggccagg catgcaatca 1550

 ccatcttcct accagaacaa caactatggg ctcaacatga gtagcccccc 1600

 acatgggagt cctggtcttg ccccaaacca gcagaatatc atgatttctc 1650

 ctcgtaatcg tgggagtcca aagatagcct cacatcagtt ttctcctgtt 1700

 gcaggtgtgc actctcccat ggcatcttct ggcaatactg ggaaccacag 1750

 cttttccagc agctctctca gtgccctgca agccatcagt gaaggtgtgg 1800

 ggacttccct tttatctact ctgtcatcac caggccccaa attggataac 1850

 tctcccaata tgaatattac ccaaccaagt aaagtaagca atcaggattc 1900

 caagagtcct ctgggctttt attgcgacca aaatccagtg gagagttcaa 1950

 tgtgtcagtc aaatagcaga gatcacctca gtgacaaaga aagtaaggag 2000

 agcagtgttg agggggcaga gaatcaaagg ggtcctttgg aaagcaaagg 2050

 tcataaaaaa ttactgcagt tacttacctg ttcttctgat gaccggggtc 2100

 attcctcctt gaccaactcc cccctagatt caagttgtaa agaatcttct 2150

 gttagtgtca ccagcccctc tggagtctcc tcctctacat ctggaggagt 2200

 atcctctaca tccaatatgc atgggtcact gttacaagag aagcaccgga 2250

 ttttgcacaa gttgctgcag aatgggaatt caccagctga ggtagccaag 2300

 attactgcag aagccactgg gaaagacacc agcagtataa cttcttgtgg 2350

 ggacggaaat gttgtcaagc aggagcagct aagtcctaag aagaaggaga 2400

 ataatgcact tcttagatac ctgctggaca gggatgatcc tagtgatgca 2450

 ctctctaaag aactacagcc ccaagtggaa ggagtggata ataaaatgag 2500

 tcagtgcacc agctccacca ttcctagctc aagtcaagag aaagacccta 2550

 aaattaagac agagacaagt gaagagggat ctggagactt ggataatcta 2600

 gatgctattc ttggtgatct gactagttct gacttttaca ataattccat 2650

 atcctcaaat ggtagtcatc tggggactaa gcaacaggtg tttcaaggaa 2700

 ctaattctct gggtttgaaa agttcacagt ctgtgcagtc tattcgtcct 2750

 ccatataacc gagcagtgtc tctggatagc cctgtttctg ttggctcaag 2800

 tcctccagta aaaaatatca gtgctttccc catgttacca aagcaaccca 2850

 tgttgggtgg gaatccaaga atgatggata gtcaggaaaa ttatggctca 2900

 agtatgggtg ggccaaaccg aaatgtgact gtgactcaga ctccttcctc 2950

 aggagactgg ggcttaccaa actcaaaggc cggcagaatg gaacctatga 3000

 attcaaactc catgggaaga ccaggaggag attataatac ttctttaccc 3050

 agacctgcac tgggtggctc tattcccaca ttgcctcttc ggtctaatag 3100

 cataccaggt gcgagaccag tattgcaaca gcagcagcag atgcttcaaa 3150

 tgaggcctgg tgaaatcccc atgggaatgg gggctaatcc ctatggccaa 3200

 gcagcagcat ctaaccaact gggttcctgg cccgatggca tgttgtccat 3250

 ggaacaagtt tctcatggca ctcaaaatag gcctcttctt aggaattccc 3300

 tggatgatct tgttgggcca ccttccaacc tggaaggcca gagtgacgaa 3350

 agagcattat tggaccagct gcacactctt ctcagcaaca cagatgccac 3400

 aggcctggaa gaaattgaca gagctttggg cattcctgaa cttgtcaatc 3450

 agggacaggc attagagccc aaacaggatg ctttccaagg ccaagaagca 3500

 gcagtaatga tggatcagaa ggcaggatta tatggacaga catacccagc 3550

 acaggggcct ccaatgcaag gaggctttca tcttcaggga caatcaccat 3600

 cttttaactc tatgatgaat cagatgaacc agcaaggcaa ttttcctctc 3650

 caaggaatgc acccacgagc caacatcatg agaccccgga caaacacccc 3700

 caagcaactt agaatgcagc ttcagcagag gctgcagggc cagcagtttt 3750

 tgaatcagag ccgacaggca cttgaattga aaatggaaaa ccctactgct 3800

 ggtggtgctg cggtgatgag gcctatgatg cagccccagc agggttttct 3850

 taatgctcaa atggtcgccc aacgcagcag agagctgcta agtcatcact 3900

 tccgacaaca gagggtggct atgatgatgc agcagcagca gcagcagcaa 3950

 cagcagcagc agcagcagca gcagcagcaa cagcaacagc aacagcaaca 4000

 gcagcaacag cagcaaaccc aggccttcag cccacctcct aatgtgactg 4050

 cttcccccag catggatggg cttttggcag gacccacaat gccacaagct 4100

 cctccgcaac agtttccata tcaaccaaat tatggaatgg gacaacaacc 4150

 agatccagcc tttggtcgag tgtctagtcc tcccaatgca atgatgtcgt 4200

 caagaatggg tccctcccag aatcccatga tgcaacaccc gcaggctgca 4250

 tccatctatc agtcctcaga aatgaagggc tggccatcag gaaatttggc 4300

 caggaacagc tccttttccc agcagcagtt tgcccaccag gggaatcctg 4350

 cagtgtatag tatggtgcac atgaatggca gcagtggtca catgggacag 4400

 atgaacatga accccatgcc catgtctggc atgcctatgg gtcctgatca 4450

 gaaatactgc tgacatctct gcaccaggac ctcttaagga aaccactgta 4500

 caaatgacac tgcactagga ttattgggaa ggaatcattg ttccaggcat 4550

 ccatcttgga agaaaggacc agctttgagc tccatcaagg gtattttaag 4600

 tgatgtcatt tgagcaggac tggattttaa gccgaagggc aatatctacg 4650

 tgtttttccc ccctccttct gctgtgtatc atggtgttca aaacagaaat 4700

 gttttttggc attccacctc ctagggatat aattctggag acatggagtg 4750

 ttactgatca taaaactttt gtgtcacttt tttctgcctt gctagccaaa 4800

 atctcttaaa tacacgtagg tgggccagag aacattggaa gaatcaagag 4850

 agattagaat atctggtttc tctagttgca gtattggaca aagagcatag 4900

 tcccagcctt caggtgtagt agttctgtgt tgaccctttg tccagtggaa 4950

 ttggtgattc tgaattgtcc tttactaatg gtgttgagtt gctctgtccc 5000

 tattatttgc cctaggcttt ctcctaatga aggttttcat ttgccattca 5050

 tgtcctgtaa tacttcacct ccaggaactg tcatggatgt ccaaatggct 5100

 ttgcagaaag gaaatgagat gacagtattt aatcgcagca gtagcaaact 5150

 tttcacatgc taatgtgcag ctgagtgcac tttatttaaa aagaatggat 5200

 aaatgcaata ttcttgaggt cttgagggaa tagtgaaaca cattcctggt 5250

 ttttgcctac acttacgtgt tagacaagaa ctatgatttt ttttttaaag 5300

 tactggtgtc accctttgcc tatatggtag agcaataatg ctttttaaaa 5350

 ataaacttct gaaaacccaa ggccaggtac tgcattctga atcagaatct 5400

 cgcagtgttt ctgtgaatag atttttttgt aaatatgacc tttaagatat 5450

 tgtattatgt aaaatatgta tatacctttt tttgtaggtc acaacaactc 5500

 atttttacag agtttgtgaa gctaaatatt taacattgtt gatttcagta 5550

 agctgtgtgg tgaggctacc agtggaagag acatcccttg acttttgtgg 5600

 cctgggggag gggtagtgct ccacagcttt tccttcccca ccccccagcc 5650

 ttagatgcct cgctcttttc aatctcttaa tctaaatgct ttttaaagag 5700

 attatttgtt tagatgtagg cattttaatt ttttaaaaat tcctctacca 5750

 gaactaagca ctttgttaat ttggggggaa agaatagata tggggaaata 5800

 aacttaaaaa aaaatcagga atttaaaaaa acgagcaatt tgaagagaat 5850

 cttttggatt ttaagcagtc cgaaataata gcaattcatg ggctgtgtgt 5900

 gtgtgtgtat gtgtgtgtgt gtgtgtgtat gtttaattat gttacctttt 5950

 catccccttt aggagcgttt tcagattttg gttgctaaga cctgaatccc 6000

 atattgagat ctcgagtaga atccttggtg tggtttctgg tgtctgctca 6050

 gctgtcccct cattctacta atgtgatgct ttcattatgt ccctgtggat 6100

 tagaatagtg tcagttattt cttaagtaac tcagtaccca gaacagccag 6150

 ttttactgtg attcagagcc acagtctaac tgagcacctt ttaaacccct 6200

 ccctcttctg ccccctacca cttttctgct gttgcctctc tttgacacct 6250

 gttttagtca gttgggagga agggaaaaat caagtttaat tccctttatc 6300

 tgggttaatt catttggttc aaatagttga cggaattggg tttctgaatg 6350

 tctgtgaatt tcagaggtct ctgctagcct tggtatcatt ttctagcaat 6400

 aactgagagc cagttaattt taagaatttc acacatttag ccaatctttc 6450

 tagatgtctc tgaaggtaag atcatttaat atctttgata tgcttacgag 6500

 taagtgaatc ctgattattt ccagacccac caccagagtg gatcttattt 6550

 tcaaagcagt atagacaatt atgagtttgc cctctttccc ctaccaagtt 6600

 caaaatatat ctaagaaaga ttgtaaatcc gaaaacttcc attgtagtgg 6650

 cctgtgcttt tcagatagta tactctcctg tttggagaca gaggaagaac 6700

 caggtcagtc tgtctctttt tcagctcaat tgtatctgac ccttctttaa 6750

 gttatgtgtg tggggagaaa tagaatggtg ctcttatctt tcttgacttt 6800

 aaaaaaatta ttaaaaacaa aaaaaaaaaa aaaaa 6835

<210> 5734
<211> 1420
<212> PRT
<213> Homo sapien

<400> 5734
 Met Ser Gly Leu Gly Glu Asn Leu Asp Pro Leu Ala Ser Asp Ser
   1               5                  10                  15

 Arg Lys Arg Lys Leu Pro Cys Asp Thr Pro Gly Gln Gly Leu Thr
                  20                  25                  30

 Cys Ser Gly Glu Lys Arg Arg Arg Glu Gln Glu Ser Lys Tyr Ile
                  35                  40                  45

 Glu Glu Leu Ala Glu Leu Ile Ser Ala Asn Leu Ser Asp Ile Asp
                  50                  55                  60

 Asn Phe Asn Val Lys Pro Asp Lys Cys Ala Ile Leu Lys Glu Thr
                  65                  70                  75

 Val Arg Gln Ile Arg Gln Ile Lys Glu Gln Gly Lys Thr Ile Ser
                  80                  85                  90

 Asn Asp Asp Asp Val Gln Lys Ala Asp Val Ser Ser Thr Gly Gln
                  95                 100                 105

 Gly Val Ile Asp Lys Asp Ser Leu Gly Pro Leu Leu Leu Gln Ala
                 110                 115                 120

 Leu Asp Gly Phe Leu Phe Val Val Asn Arg Asp Gly Asn Ile Val
                 125                 130                 135

 Phe Val Ser Glu Asn Val Thr Gln Tyr Leu Gln Tyr Lys Gln Glu
                 140                 145                 150

 Asp Leu Val Asn Thr Ser Val Tyr Asn Ile Leu His Glu Glu Asp
                 155                 160                 165

 Arg Lys Asp Phe Leu Lys Asn Leu Pro Lys Ser Thr Val Asn Gly
                 170                 175                 180

 Val Ser Trp Thr Asn Glu Thr Gln Arg Gln Lys Ser His Thr Phe
                 185                 190                 195

 Asn Cys Arg Met Leu Met Lys Thr Pro His Asp Ile Leu Glu Asp
                 200                 205                 210

 Ile Asn Ala Ser Pro Glu Met Arg Gln Arg Tyr Glu Thr Met Gln
                 215                 220                 225

 Cys Phe Ala Leu Ser Gln Pro Arg Ala Met Met Glu Glu Gly Glu
                 230                 235                 240

 Asp Leu Gln Ser Cys Met Ile Cys Val Ala Arg Arg Ile Thr Thr
                 245                 250                 255

 Gly Glu Arg Thr Phe Pro Ser Asn Pro Glu Ser Phe Ile Thr Arg
                 260                 265                 270

 His Asp Leu Ser Gly Lys Val Val Asn Ile Asp Thr Asn Ser Leu
                 275                 280                 285

 Arg Ser Ser Met Arg Pro Gly Phe Glu Asp Ile Ile Arg Arg Cys
                 290                 295                 300

 Ile Gln Arg Phe Phe Ser Leu Asn Asp Gly Gln Ser Trp Ser Gln
                 305                 310                 315

 Lys Arg His Tyr Gln Glu Ala Tyr Leu Asn Gly His Ala Glu Thr
                 320                 325                 330

 Pro Val Tyr Arg Phe Ser Leu Ala Asp Gly Thr Ile Val Thr Ala
                 335                 340                 345

 Gln Thr Lys Ser Lys Leu Phe Arg Asn Pro Val Thr Asn Asp Arg
                 350                 355                 360

 His Gly Phe Val Ser Thr His Phe Leu Gln Arg Glu Gln Asn Gly
                 365                 370                 375

 Tyr Arg Pro Asn Pro Asn Pro Val Gly Gln Gly Ile Arg Pro Pro
                 380                 385                 390

 Met Ala Gly Cys Asn Ser Ser Val Gly Gly Met Ser Met Ser Pro
                 395                 400                 405

 Asn Gln Gly Leu Gln Met Pro Ser Ser Arg Ala Tyr Gly Leu Ala
                 410                 415                 420

 Asp Pro Ser Thr Thr Gly Gln Met Ser Gly Ala Arg Tyr Gly Gly
                 425                 430                 435

 Ser Ser Asn Ile Ala Ser Leu Thr Pro Gly Pro Gly Met Gln Ser
                 440                 445                 450

 Pro Ser Ser Tyr Gln Asn Asn Asn Tyr Gly Leu Asn Met Ser Ser
                 455                 460                 465

 Pro Pro His Gly Ser Pro Gly Leu Ala Pro Asn Gln Gln Asn Ile
                 470                 475                 480

 Met Ile Ser Pro Arg Asn Arg Gly Ser Pro Lys Ile Ala Ser His
                 485                 490                 495

 Gln Phe Ser Pro Val Ala Gly Val His Ser Pro Met Ala Ser Ser
                 500                 505                 510

 Gly Asn Thr Gly Asn His Ser Phe Ser Ser Ser Ser Leu Ser Ala
                 515                 520                 525

 Leu Gln Ala Ile Ser Glu Gly Val Gly Thr Ser Leu Leu Ser Thr
                 530                 535                 540

 Leu Ser Ser Pro Gly Pro Lys Leu Asp Asn Ser Pro Asn Met Asn
                 545                 550                 555

 Ile Thr Gln Pro Ser Lys Val Ser Asn Gln Asp Ser Lys Ser Pro
                 560                 565                 570

 Leu Gly Phe Tyr Cys Asp Gln Asn Pro Val Glu Ser Ser Met Cys
                 575                 580                 585

 Gln Ser Asn Ser Arg Asp His Leu Ser Asp Lys Glu Ser Lys Glu
                 590                 595                 600

 Ser Ser Val Glu Gly Ala Glu Asn Gln Arg Gly Pro Leu Glu Ser
                 605                 610                 615

 Lys Gly His Lys Lys Leu Leu Gln Leu Leu Thr Cys Ser Ser Asp
                 620                 625                 630

 Asp Arg Gly His Ser Ser Leu Thr Asn Ser Pro Leu Asp Ser Ser
                 635                 640                 645

 Cys Lys Glu Ser Ser Val Ser Val Thr Ser Pro Ser Gly Val Ser
                 650                 655                 660

 Ser Ser Thr Ser Gly Gly Val Ser Ser Thr Ser Asn Met His Gly
                 665                 670                 675

 Ser Leu Leu Gln Glu Lys His Arg Ile Leu His Lys Leu Leu Gln
                 680                 685                 690

 Asn Gly Asn Ser Pro Ala Glu Val Ala Lys Ile Thr Ala Glu Ala
                 695                 700                 705

 Thr Gly Lys Asp Thr Ser Ser Ile Thr Ser Cys Gly Asp Gly Asn
                 710                 715                 720

 Val Val Lys Gln Glu Gln Leu Ser Pro Lys Lys Lys Glu Asn Asn
                 725                 730                 735

 Ala Leu Leu Arg Tyr Leu Leu Asp Arg Asp Asp Pro Ser Asp Ala
                 740                 745                 750

 Leu Ser Lys Glu Leu Gln Pro Gln Val Glu Gly Val Asp Asn Lys
                 755                 760                 765

 Met Ser Gln Cys Thr Ser Ser Thr Ile Pro Ser Ser Ser Gln Glu
                 770                 775                 780

 Lys Asp Pro Lys Ile Lys Thr Glu Thr Ser Glu Glu Gly Ser Gly
                 785                 790                 795

 Asp Leu Asp Asn Leu Asp Ala Ile Leu Gly Asp Leu Thr Ser Ser
                 800                 805                 810

 Asp Phe Tyr Asn Asn Ser Ile Ser Ser Asn Gly Ser His Leu Gly
                 815                 820                 825

 Thr Lys Gln Gln Val Phe Gln Gly Thr Asn Ser Leu Gly Leu Lys
                 830                 835                 840

 Ser Ser Gln Ser Val Gln Ser Ile Arg Pro Pro Tyr Asn Arg Ala
                 845                 850                 855

 Val Ser Leu Asp Ser Pro Val Ser Val Gly Ser Ser Pro Pro Val
                 860                 865                 870

 Lys Asn Ile Ser Ala Phe Pro Met Leu Pro Lys Gln Pro Met Leu
                 875                 880                 885

 Gly Gly Asn Pro Arg Met Met Asp Ser Gln Glu Asn Tyr Gly Ser
                 890                 895                 900

 Ser Met Gly Gly Pro Asn Arg Asn Val Thr Val Thr Gln Thr Pro
                 905                 910                 915

 Ser Ser Gly Asp Trp Gly Leu Pro Asn Ser Lys Ala Gly Arg Met
                 920                 925                 930

 Glu Pro Met Asn Ser Asn Ser Met Gly Arg Pro Gly Gly Asp Tyr
                 935                 940                 945

 Asn Thr Ser Leu Pro Arg Pro Ala Leu Gly Gly Ser Ile Pro Thr
                 950                 955                 960

 Leu Pro Leu Arg Ser Asn Ser Ile Pro Gly Ala Arg Pro Val Leu
                 965                 970                 975

 Gln Gln Gln Gln Gln Met Leu Gln Met Arg Pro Gly Glu Ile Pro
                 980                 985                 990

 Met Gly Met Gly Ala Asn Pro Tyr Gly Gln Ala Ala Ala Ser Asn
                 995                1000                1005

 Gln Leu Gly Ser Trp Pro Asp Gly Met Leu Ser Met Glu Gln Val
                1010                1015                1020

 Ser His Gly Thr Gln Asn Arg Pro Leu Leu Arg Asn Ser Leu Asp
                1025                1030                1035

 Asp Leu Val Gly Pro Pro Ser Asn Leu Glu Gly Gln Ser Asp Glu
                1040                1045                1050

 Arg Ala Leu Leu Asp Gln Leu His Thr Leu Leu Ser Asn Thr Asp
                1055                1060                1065

 Ala Thr Gly Leu Glu Glu Ile Asp Arg Ala Leu Gly Ile Pro Glu
                1070                1075                1080

 Leu Val Asn Gln Gly Gln Ala Leu Glu Pro Lys Gln Asp Ala Phe
                1085                1090                1095

 Gln Gly Gln Glu Ala Ala Val Met Met Asp Gln Lys Ala Gly Leu
                1100                1105                1110

 Tyr Gly Gln Thr Tyr Pro Ala Gln Gly Pro Pro Met Gln Gly Gly
                1115                1120                1125

 Phe His Leu Gln Gly Gln Ser Pro Ser Phe Asn Ser Met Met Asn
                1130                1135                1140

 Gln Met Asn Gln Gln Gly Asn Phe Pro Leu Gln Gly Met His Pro
                1145                1150                1155

 Arg Ala Asn Ile Met Arg Pro Arg Thr Asn Thr Pro Lys Gln Leu
                1160                1165                1170

 Arg Met Gln Leu Gln Gln Arg Leu Gln Gly Gln Gln Phe Leu Asn
                1175                1180                1185

 Gln Ser Arg Gln Ala Leu Glu Leu Lys Met Glu Asn Pro Thr Ala
                1190                1195                1200

 Gly Gly Ala Ala Val Met Arg Pro Met Met Gln Pro Gln Gln Gly
                1205                1210                1215

 Phe Leu Asn Ala Gln Met Val Ala Gln Arg Ser Arg Glu Leu Leu
                1220                1225                1230

 Ser His His Phe Arg Gln Gln Arg Val Ala Met Met Met Gln Gln
                1235                1240                1245

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln
                1250                1255                1260

 Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Thr Gln Ala
                1265                1270                1275

 Phe Ser Pro Pro Pro Asn Val Thr Ala Ser Pro Ser Met Asp Gly
                1280                1285                1290

 Leu Leu Ala Gly Pro Thr Met Pro Gln Ala Pro Pro Gln Gln Phe
                1295                1300                1305

 Pro Tyr Gln Pro Asn Tyr Gly Met Gly Gln Gln Pro Asp Pro Ala
                1310                1315                1320

 Phe Gly Arg Val Ser Ser Pro Pro Asn Ala Met Met Ser Ser Arg
                1325                1330                1335

 Met Gly Pro Ser Gln Asn Pro Met Met Gln His Pro Gln Ala Ala
                1340                1345                1350

 Ser Ile Tyr Gln Ser Ser Glu Met Lys Gly Trp Pro Ser Gly Asn
                1355                1360                1365

 Leu Ala Arg Asn Ser Ser Phe Ser Gln Gln Gln Phe Ala His Gln
                1370                1375                1380

 Gly Asn Pro Ala Val Tyr Ser Met Val His Met Asn Gly Ser Ser
                1385                1390                1395

 Gly His Met Gly Gln Met Asn Met Asn Pro Met Pro Met Ser Gly
                1400                1405                1410

 Met Pro Met Gly Pro Asp Gln Lys Tyr Cys
                1415                1420

<210> 5735
<211> 1953
<212> DNA
<213> Homo sapien

<400> 5735
 gcagaccttg cttcatgagc aagctcatct ctggaacaaa ctggcaaagc 50

 atctctgctg gtgttcatca gaacagacac catggcagag catgattacc 100

 atgaagacta tgggttcagc agtttcaatg acagcagcca ggaggagcat 150

 caagacttcc tgcagttcag caaggtcttt ctgccctgca tgtacctggt 200

 ggtgtttgtc tgtggtctgg tggggaactc tctggtgctg gtcatatcca 250

 tcttctacca taagttgcag agcctgacgg atgtgttcct ggtgaaccta 300

 cccctggctg acctggtgtt tgtctgcact ctgcccttct gggcctatgc 350

 aggcatccat gaatgggtgt ttggccaggt catgtgcaag agcctactgg 400

 gcatctacac tattaacttc tacacgtcca tgctcatcct cacctgcatc 450

 actgtggatc gtttcattgt agtggttaag gccaccaagg cctacaacca 500

 gcaagccaag aggatgacct ggggcaaggt caccagcttg ctcatctggg 550

 tgatatccct gctggtttcc ttgccccaaa ttatctatgg caatgtcttt 600

 aatctcgaca agctcatatg tggttaccat gacgaggcaa tttccactgt 650

 ggttcttgcc acccagatga cactggggtt cttcttgcca ctgctcacca 700

 tgattgtctg ctattcagtc ataatcaaaa cactgcttca tgctggaggc 750

 ttccagaagc acagatctct aaagatcatc ttcctggtga tggctgtgtt 800

 cctgctgacc cagatgccct tcaacctcat gaagttcatc cgcagcacac 850

 actgggaata ctatgccatg accagctttc actacaccat catggtgaca 900

 gaggccatcg catacctgag ggcctgcctt aaccctgtgc tctatgcctt 950

 tgtcagcctg aagtttcgaa agaacttctg gaaacttgtg aaggacattg 1000

 gttgcctccc ttaccttggg gtctcacatc aatggaaatc ttctgaggac 1050

 aattccaaga ctttttctgc ctcccacaat gtggaggcca ccagcatgtt 1100

 ccagttatag gccttgccag ggtttcgaga agctgctctg gaatttgcaa 1150

 gtcatggctg tgccctcttg atgtggtgag gcaggctttg tttatagctt 1200

 gcgcattctc atggagaagt tatcagacac tctggctggt ttggaatgct 1250

 tcttctcagg catgaacatg tactgttctc ttcttgaaca ctcatgctga 1300

 aagcccaagt agggggtcta aaatttttaa ggactttcct tcctccatct 1350

 ccaagaatgc tgaaaccaag ggggatgaca tgtgactcct atgatctcag 1400

 gttctccttg attgggactg gggctgaagg ttgaagaggt gagcacggcc 1450

 aacaaagctg ttgatggtag gtggcacact gggtgcccaa gctcagaagg 1500

 ctcttctgac tactgggcaa agagtgtaga tcagagcagc agtgaaaaca 1550

 agtgctggca ccaccaggca cctcacagaa atgagatcag gctctgcctc 1600

 accttggggc ttgacttttg tataggtaga tgttcagatt gctttgatta 1650

 atccagaata actagcacca gggactatga atgggcaaaa ctgaattata 1700

 agaggctgat aattccagtg gtccatggaa tgcttgaaaa atgtgcaaaa 1750

 cagcgtttaa gactgtaatg aatctaagca gcatttctga agtggactct 1800

 ttggtggctt tgcattttaa aaatgaaatt ttccaatgtc tgccacacaa 1850

 acgtatgtaa atgtatatac ccacacacat acacacatat gtcatatatt 1900

 actagcatat gagtttcata gctaagaaat aaaactgtta aagtctccaa 1950

 act 1953

<210> 5736
<211> 342
<212> PRT
<213> Homo sapien

<400> 5736
 Met Ala Glu His Asp Tyr His Glu Asp Tyr Gly Phe Ser Ser Phe
   1               5                  10                  15

 Asn Asp Ser Ser Gln Glu Glu His Gln Asp Phe Leu Gln Phe Ser
                  20                  25                  30

 Lys Val Phe Leu Pro Cys Met Tyr Leu Val Val Phe Val Cys Gly
                  35                  40                  45

 Leu Val Gly Asn Ser Leu Val Leu Val Ile Ser Ile Phe Tyr His
                  50                  55                  60

 Lys Leu Gln Ser Leu Thr Asp Val Phe Leu Val Asn Leu Pro Leu
                  65                  70                  75

 Ala Asp Leu Val Phe Val Cys Thr Leu Pro Phe Trp Ala Tyr Ala
                  80                  85                  90

 Gly Ile His Glu Trp Val Phe Gly Gln Val Met Cys Lys Ser Leu
                  95                 100                 105

 Leu Gly Ile Tyr Thr Ile Asn Phe Tyr Thr Ser Met Leu Ile Leu
                 110                 115                 120

 Thr Cys Ile Thr Val Asp Arg Phe Ile Val Val Val Lys Ala Thr
                 125                 130                 135

 Lys Ala Tyr Asn Gln Gln Ala Lys Arg Met Thr Trp Gly Lys Val
                 140                 145                 150

 Thr Ser Leu Leu Ile Trp Val Ile Ser Leu Leu Val Ser Leu Pro
                 155                 160                 165

 Gln Ile Ile Tyr Gly Asn Val Phe Asn Leu Asp Lys Leu Ile Cys
                 170                 175                 180

 Gly Tyr His Asp Glu Ala Ile Ser Thr Val Val Leu Ala Thr Gln
                 185                 190                 195

 Met Thr Leu Gly Phe Phe Leu Pro Leu Leu Thr Met Ile Val Cys
                 200                 205                 210

 Tyr Ser Val Ile Ile Lys Thr Leu Leu His Ala Gly Gly Phe Gln
                 215                 220                 225

 Lys His Arg Ser Leu Lys Ile Ile Phe Leu Val Met Ala Val Phe
                 230                 235                 240

 Leu Leu Thr Gln Met Pro Phe Asn Leu Met Lys Phe Ile Arg Ser
                 245                 250                 255

 Thr His Trp Glu Tyr Tyr Ala Met Thr Ser Phe His Tyr Thr Ile
                 260                 265                 270

 Met Val Thr Glu Ala Ile Ala Tyr Leu Arg Ala Cys Leu Asn Pro
                 275                 280                 285

 Val Leu Tyr Ala Phe Val Ser Leu Lys Phe Arg Lys Asn Phe Trp
                 290                 295                 300

 Lys Leu Val Lys Asp Ile Gly Cys Leu Pro Tyr Leu Gly Val Ser
                 305                 310                 315

 His Gln Trp Lys Ser Ser Glu Asp Asn Ser Lys Thr Phe Ser Ala
                 320                 325                 330

 Ser His Asn Val Glu Ala Thr Ser Met Phe Gln Leu
                 335                 340

<210> 5737
<211> 2603
<212> DNA
<213> Homo sapien

<400> 5737
 ccacgcgtcc gcgctcccct cagctcctgc agtgctaatt aagggaggga 50

 gcagcgggga gcttgcagtg accaagaggg tgttgaggct aggaggccac 100

 gataaacagg atacgataaa agtccttaac caagacgcag atgggaagaa 150

 gcgttagagc gagcagcact cacatctcaa gaaccagcct ttcaaacagt 200

 ttccagagat ggattatcct actttacttt tggctcttct tcatgtatac 250

 agagctctat gtgaagaggt gctttggcat acatcagttc cctttgccga 300

 gaacatgtct ctagaatgtg tgtatccatc aatgggcatc ttaacacagg 350

 tggagtggtt caagatcggg acccagcagg attccatagc cattttcagc 400

 cctactcatg gcatggtcat aaggaagccc tatgctgaga gggtttactt 450

 tttgaattca acgatggctt ccaataacat gactcttttc tttcggaatg 500

 cctctgaaga tgatgttggc tactattcct gctctcttta cacttaccca 550

 cagggaactt ggcagaaggt gatacaggtg gttcagtcag atagttttga 600

 ggcagctgtg ccatcaaata gccacattgt ttcggaacct ggaaagaatg 650

 tcacactcac ttgtcagcct cagatgacgt ggcctgtgca ggcagtgagg 700

 tgggaaaaga tccagccccg tcagatcgac ctcttaactt actgcaactt 750

 ggtccatggc agaaatttca cctccaagtt cccaagacaa atagtgagca 800

 actgcagcca cggaaggtgg agcgtcatcg tcatccccga tgtcacagtc 850

 tcagactcgg ggctttaccg ctgctacttg caggccagcg caggagaaaa 900

 cgaaaccttc gtgatgagat tgactgtagc cgagggtaaa accgataacc 950

 aatataccct ctttgtggct ggagggacag ttttattgtt gttgtttgtt 1000

 atctcaatta ccaccatcat tgtcattttc cttaacagaa ggagaaggag 1050

 agagagaaga gatctattta cagagtcctg ggatacacag aaggcaccca 1100

 ataactatag aagtcccatc tctaccggtc aacctaccaa tcaatccatg 1150

 gatgatacaa gagaggatat ttatgtcaac tatccaacct tctctcgcag 1200

 accaaagact agagtttaag cttattcttg acatgagtgc attagtaatg 1250

 actcttatgt actcatgcat ggatctttat gcaatttttt tccactaccc 1300

 aaggtctacc ttagatacta gttgtctgaa ttgagttact ttgataggaa 1350

 aaatacttca ttacctaaaa tcatttttca tagaactgtt tcagaaaacc 1400

 tgactctaac tggtttatat acaaaagaaa acttactgta tcatataaca 1450

 gaatgatcca ggggagatta agctttgggc aagggctatt taccagggct 1500

 taaatgttgt gtctagaatt aagtatgggc ataaactggc ttctgaatcc 1550

 ctttccagag tgttggatcc atttccctgg tcttggcctc actctcatgc 1600

 aggctttcct cttgtgttgg caagatggct gccaactctt ggcaattcat 1650

 acatccttgt ttctgtctgg tagagagttt gcttctcaaa tggagcaaac 1700

 aaatttgatt attttttcat tgttaaatag gcaacatgac cagaaaggat 1750

 ggaatggctt aagtaaacta agggttcact tctagagctg agaagcaggg 1800

 tcaaagcaca atactgggca attcagagca tggttagaag aggaaagggg 1850

 agtctcaaag ctggagagtt taccaacaaa tattgactgc agtgattaac 1900

 caagacattt ttgttaacta aaaagtgaaa tatgggatgg attctagaaa 1950

 tggggtatct ctgtccatac ttctagaatc cactctatca gcatagtcca 2000

 gaagaatacc tggcagtaga agaaatgaat attcaagagg aagataaatg 2050

 cgagagggca atcctttact attctcatat ttatttatct ctcattctgt 2100

 atagaattct tgccgccatc ccaggtctag ccttaggagc aaatgtagta 2150

 gatagtcgaa taataaataa cttaatgttt tggacatatt ttgtctactt 2200

 ttgagaatta tttttaatat gtaaattctc tcaaaagggt caggcaccta 2250

 gttattattt tttaatgatt atgtgaaagt tgaatataat ataccactaa 2300

 aagtgacagt tgaaagtggt ggcataggat ggtagggtag aaatttggga 2350

 gggaaaaaag aaattgggag ggtacaggca acaggagaaa ggaatcaaac 2400

 cacagaaaaa tacaaaggga aacttctgct tcactattca gacaaagaca 2450

 gccctaatga catcaccaac agtcaaagca attagagacc atacctaata 2500

 ttgtttaaat tctagatgta ggctaacaat gaaaagtatt tgccaaactg 2550

 aataaaactg tcatggttac cttgaaaaaa aaaaaaaaaa aaaaaaaaaa 2600

 aaa 2603

<210> 5738
<211> 336
<212> PRT
<213> Homo sapien

<400> 5738
 Met Asp Tyr Pro Thr Leu Leu Leu Ala Leu Leu His Val Tyr Arg
   1               5                  10                  15

 Ala Leu Cys Glu Glu Val Leu Trp His Thr Ser Val Pro Phe Ala
                  20                  25                  30

 Glu Asn Met Ser Leu Glu Cys Val Tyr Pro Ser Met Gly Ile Leu
                  35                  40                  45

 Thr Gln Val Glu Trp Phe Lys Ile Gly Thr Gln Gln Asp Ser Ile
                  50                  55                  60

 Ala Ile Phe Ser Pro Thr His Gly Met Val Ile Arg Lys Pro Tyr
                  65                  70                  75

 Ala Glu Arg Val Tyr Phe Leu Asn Ser Thr Met Ala Ser Asn Asn
                  80                  85                  90

 Met Thr Leu Phe Phe Arg Asn Ala Ser Glu Asp Asp Val Gly Tyr
                  95                 100                 105

 Tyr Ser Cys Ser Leu Tyr Thr Tyr Pro Gln Gly Thr Trp Gln Lys
                 110                 115                 120

 Val Ile Gln Val Val Gln Ser Asp Ser Phe Glu Ala Ala Val Pro
                 125                 130                 135

 Ser Asn Ser His Ile Val Ser Glu Pro Gly Lys Asn Val Thr Leu
                 140                 145                 150

 Thr Cys Gln Pro Gln Met Thr Trp Pro Val Gln Ala Val Arg Trp
                 155                 160                 165

 Glu Lys Ile Gln Pro Arg Gln Ile Asp Leu Leu Thr Tyr Cys Asn
                 170                 175                 180

 Leu Val His Gly Arg Asn Phe Thr Ser Lys Phe Pro Arg Gln Ile
                 185                 190                 195

 Val Ser Asn Cys Ser His Gly Arg Trp Ser Val Ile Val Ile Pro
                 200                 205                 210

 Asp Val Thr Val Ser Asp Ser Gly Leu Tyr Arg Cys Tyr Leu Gln
                 215                 220                 225

 Ala Ser Ala Gly Glu Asn Glu Thr Phe Val Met Arg Leu Thr Val
                 230                 235                 240

 Ala Glu Gly Lys Thr Asp Asn Gln Tyr Thr Leu Phe Val Ala Gly
                 245                 250                 255

 Gly Thr Val Leu Leu Leu Leu Phe Val Ile Ser Ile Thr Thr Ile
                 260                 265                 270

 Ile Val Ile Phe Leu Asn Arg Arg Arg Arg Arg Glu Arg Arg Asp
                 275                 280                 285

 Leu Phe Thr Glu Ser Trp Asp Thr Gln Lys Ala Pro Asn Asn Tyr
                 290                 295                 300

 Arg Ser Pro Ile Ser Thr Gly Gln Pro Thr Asn Gln Ser Met Asp
                 305                 310                 315

 Asp Thr Arg Glu Asp Ile Tyr Val Asn Tyr Pro Thr Phe Ser Arg
                 320                 325                 330

 Arg Pro Lys Thr Arg Val
                 335

<210> 5739
<211> 4181
<212> DNA
<213> Homo sapien

<400> 5739
 atgaacgcgg ccctctgtaa tggcggagcg tggcggggac gggggcgaga 50

 gtgaacgatt caacccgggg gagctcagga tggcccaaca gcaggccttg 100

 aggttccgag gtccggctcc cccaccaaat gcagtgatgc gaggcccacc 150

 acctctgatg cgacctcctc caccttttgg tatgatgcga ggccctcctc 200

 caccaccacg gccgcccttt ggacgtcctc cttttgatcc taatatgccg 250

 ccaatgcctc ctccaggagg gatacctcca cctatgggcc ctccacacct 300

 ccagagacca cctttcatgc ctcctcccat gagttccatg cctcctcctc 350

 cgggtatgat gtttccacca ggaatgcctc ctgtgactgc tcctggtact 400

 ccagcactac ctcctacgga ggagatatgg gttgaaaata aaactccaga 450

 tgggaaggtt tattattata atgctcggac acgtgaatct gcatggacca 500

 agccagatgg agttaaggtt attcagcaat cagaactgac acctatgctt 550

 gcagcccagg cacaggttca ggctcaggcc caggcgcagg ctcaggccca 600

 ggcgcaggct caggcccagg cacaagctca ggcccaggct caggctcagg 650

 cccaggccca ggcccaggcc caggcccagg cccaagccca agcccaggcc 700

 caggctcagg ctcaggcaca agctcaggcc caggcccagg ctcaggtcca 750

 ggcccaggtc caggcacaag tgcaagcaca agcagttgga gcttccaccc 800

 ctacgaccag tagcccagca cctgcagtat ccacttcaac atcatcatcc 850

 accccttcct ctaccacttc taccacaaca actgctactt cagttgcgca 900

 gacagtatca acacccacaa cacaagatca gaccccaagt tctgctgttt 950

 cagttgccac gcctacagtt agtgtttcaa ctcctgctcc tacagccaca 1000

 cctgtgcaaa ccgttcccca gccgcaccct cagacgttac ctcctgctgt 1050

 tcctcattca gtacctcagc caacaacagc aatacctgct tttccaccag 1100

 taatggtacc tccgtttcgt gttccccttc ctggcatgcc aattccactt 1150

 ccaggtgtag caatgatgca aatagtcagc tgcccgtatg taaagacagt 1200

 cgctaccacc aagaccggtg tattgccagg aatggcccct cctatcgtac 1250

 ccatgataca tccccaggtt gctattgcag cttcacctgc taccttagct 1300

 ggagcaacag cagtttctga atggactgaa tataaaacag cagatgggaa 1350

 gacatattat tataataata gaacattaga atcaacctgg gaaaaacccc 1400

 aagaactaaa ggaaaaagaa aagttagaag agaagattaa agagccaatt 1450

 aaagaaccct ctgaagagcc tctgccaatg gagacggagg aggaggatcc 1500

 taaagaagag cctataaagg agataaagga ggagcccaaa gaagaggaga 1550

 tgactgaaga agaaaaggct gcccagaagg caaagccagt tgctactgct 1600

 cctattcctg gtactccatg gtgtgtcgtt tggactggtg atgagcgggt 1650

 cttcttttat aatcccacca ctcgtctttc tatgtgggac cgacctgatg 1700

 atctgattgg cagggcagat gttgacaaaa ttattcagga gccccctcat 1750

 aaaaaaggaa tggaggaatt gaagaaacta aggcacccaa ctccgacaat 1800

 gctgtcgatc caaaagtggc aattctctat gagtgcaatt aaagaggaac 1850

 aagaattaat ggaagaaatt aatgaagatg agcctgttaa agcaaaaaaa 1900

 cggaagagag acgataataa agacattgac tcagagaaag aagctgccat 1950

 ggaagctgaa attaaagctg cccgagaaag ggccattgtc cctctggagg 2000

 ctcgaatgaa gcagttcaag gacatgctgc tagagagagg ggtgtctgct 2050

 ttttcaacgt gggagaagga gttgcacaag atagtttttg atccccggta 2100

 cttacttctc aatcctaaag agagaaaaca ggtgtttgat cagtatgtaa 2150

 agaccagggc agaggaagaa cgcagggaaa agaaaaataa aataatgcaa 2200

 gccaaggaag atttcaaaaa aatgatggaa gaagcaaaat ttaatccaag 2250

 agcaactttt agtgaatttg cagccaagca tgctaaagat tcaagattca 2300

 aagcaattga aaagatgaaa gaccgagaag ccttgtttaa tgagtttgtg 2350

 gccgctgcta ggaagaaaga gaaagaagat tcgaagacca gaggtgagaa 2400

 gattaaatcg gatttctttg aactattatc taatcatcac ttggacagtc 2450

 agtctcgatg gagcaaagta aaagacaaag tagaaagtga tccacgttac 2500

 aaagcagtag atagttcatc aatgagagaa gaccttttca aacagtacat 2550

 tgaaaaaata gccaagaatt tagactcaga aaaagaaaag gagcttgaaa 2600

 ggcaagcccg cattgaggca agccttcgag aacgagaaag ggaggttcaa 2650

 aaggcccgtt cagaacaaac aaaagaaata gatcgagaga gagagcagca 2700

 caaacgagaa gaagctatcc agaatttcaa agctcttctg tctgacatgg 2750

 tacgttcttc agatgtgtca tggtctgata ctcgtaggac cctccgaaaa 2800

 gatcaccgct gggaatctgg atccttattg gaaagagagg agaaagagaa 2850

 gctttttaat gaacacattg aagcacttac caaaaaaaag agagagcact 2900

 ttaggcaact tctggatgaa acttctgcaa ttaccttaac atccacgtgg 2950

 aaagaagtaa aaaaaatcat taaggaagat cctcgatgta ttaagttctc 3000

 ctccagtgac aggaaaaaac aaagagaatt tgaagaatat atcagagaca 3050

 aatatatcac agccaaagct gacttcagga cgcttttgaa agagaccaaa 3100

 tttataacat atagatccaa aaaattaatc caagaatcag atcagcacct 3150

 gaaagatgta gaaaaaattt tacagaatga caaacggtat ctagtactgg 3200

 actgtgtgcc agaggagagg cgtaaactga ttgtggcata tgttgatgac 3250

 ctggatcgcc ggggtccacc cccacctccc acagcatcgg agcccacgag 3300

 acgatcaaca aaataattct aaatactctt ccataggggc atctattcaa 3350

 aatgcttgca tgagccaatt ttcaggtttt tacatatatg tgcattagtc 3400

 aacctattgc gaaaccatct gacaaacaga aggagaagca tttgtgaaca 3450

 gtttctgaac agaacacttt ggaaatattt atgcttttct ttgtgtggca 3500

 tgactgacat acatactcaa atataggctg tctctagtaa atcttaaaat 3550

 cttgaagcta aaattcatcc ttttatgagg tgtggaagtc agtgacttgg 3600

 tgacgttctt cctagcagtg ttaatacatg caagaagtaa gagcatttgt 3650

 ggcttgaact tgccagatgc aaataccaca gactccaaga aaacccgagt 3700

 tggggtttgt tttgttttga tttttttttt ttaaagcggg taaaagagaa 3750

 aacactgaaa attgaattct tatcttccag aggctacaat tattataatg 3800

 gacaatactt ttacctttgt ctctaaagat cagattagtt ttatttgttc 3850

 acttacgtgc tttgattatc ccctctgaat tatagaccga gtcttgttgt 3900

 ttagcctaag agaagattta tgtagtaatt tcttctcagg tatggaacca 3950

 cggtcataac taacatgttg gccagaatag aaccactggt taaacatatt 4000

 ttattcacca ttaagtgatc tttatcaata ttctggatta gacaacaaat 4050

 tacctttctg ggtgtttctt gtaaactata ctcctgtttg aatgttaaac 4100

 tttgttgcta aagtttaatt ttaagatgtt tgaatgttca gtttatgtat 4150

 ttgaactaca ataaaccaac cctttttata t 4181

<210> 5740
<211> 1098
<212> PRT
<213> Homo sapien

<400> 5740
 Met Ala Glu Arg Gly Gly Asp Gly Gly Glu Ser Glu Arg Phe Asn
   1               5                  10                  15

 Pro Gly Glu Leu Arg Met Ala Gln Gln Gln Ala Leu Arg Phe Arg
                  20                  25                  30

 Gly Pro Ala Pro Pro Pro Asn Ala Val Met Arg Gly Pro Pro Pro
                  35                  40                  45

 Leu Met Arg Pro Pro Pro Pro Phe Gly Met Met Arg Gly Pro Pro
                  50                  55                  60

 Pro Pro Pro Arg Pro Pro Phe Gly Arg Pro Pro Phe Asp Pro Asn
                  65                  70                  75

 Met Pro Pro Met Pro Pro Pro Gly Gly Ile Pro Pro Pro Met Gly
                  80                  85                  90

 Pro Pro His Leu Gln Arg Pro Pro Phe Met Pro Pro Pro Met Ser
                  95                 100                 105

 Ser Met Pro Pro Pro Pro Gly Met Met Phe Pro Pro Gly Met Pro
                 110                 115                 120

 Pro Val Thr Ala Pro Gly Thr Pro Ala Leu Pro Pro Thr Glu Glu
                 125                 130                 135

 Ile Trp Val Glu Asn Lys Thr Pro Asp Gly Lys Val Tyr Tyr Tyr
                 140                 145                 150

 Asn Ala Arg Thr Arg Glu Ser Ala Trp Thr Lys Pro Asp Gly Val
                 155                 160                 165

 Lys Val Ile Gln Gln Ser Glu Leu Thr Pro Met Leu Ala Ala Gln
                 170                 175                 180

 Ala Gln Val Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala
                 185                 190                 195

 Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln
                 200                 205                 210

 Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala
                 215                 220                 225

 Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln Ala Gln
                 230                 235                 240

 Ala Gln Val Gln Ala Gln Val Gln Ala Gln Val Gln Ala Gln Ala
                 245                 250                 255

 Val Gly Ala Ser Thr Pro Thr Thr Ser Ser Pro Ala Pro Ala Val
                 260                 265                 270

 Ser Thr Ser Thr Ser Ser Ser Thr Pro Ser Ser Thr Thr Ser Thr
                 275                 280                 285

 Thr Thr Thr Ala Thr Ser Val Ala Gln Thr Val Ser Thr Pro Thr
                 290                 295                 300

 Thr Gln Asp Gln Thr Pro Ser Ser Ala Val Ser Val Ala Thr Pro
                 305                 310                 315

 Thr Val Ser Val Ser Thr Pro Ala Pro Thr Ala Thr Pro Val Gln
                 320                 325                 330

 Thr Val Pro Gln Pro His Pro Gln Thr Leu Pro Pro Ala Val Pro
                 335                 340                 345

 His Ser Val Pro Gln Pro Thr Thr Ala Ile Pro Ala Phe Pro Pro
                 350                 355                 360

 Val Met Val Pro Pro Phe Arg Val Pro Leu Pro Gly Met Pro Ile
                 365                 370                 375

 Pro Leu Pro Gly Val Ala Met Met Gln Ile Val Ser Cys Pro Tyr
                 380                 385                 390

 Val Lys Thr Val Ala Thr Thr Lys Thr Gly Val Leu Pro Gly Met
                 395                 400                 405

 Ala Pro Pro Ile Val Pro Met Ile His Pro Gln Val Ala Ile Ala
                 410                 415                 420

 Ala Ser Pro Ala Thr Leu Ala Gly Ala Thr Ala Val Ser Glu Trp
                 425                 430                 435

 Thr Glu Tyr Lys Thr Ala Asp Gly Lys Thr Tyr Tyr Tyr Asn Asn
                 440                 445                 450

 Arg Thr Leu Glu Ser Thr Trp Glu Lys Pro Gln Glu Leu Lys Glu
                 455                 460                 465

 Lys Glu Lys Leu Glu Glu Lys Ile Lys Glu Pro Ile Lys Glu Pro
                 470                 475                 480

 Ser Glu Glu Pro Leu Pro Met Glu Thr Glu Glu Glu Asp Pro Lys
                 485                 490                 495

 Glu Glu Pro Ile Lys Glu Ile Lys Glu Glu Pro Lys Glu Glu Glu
                 500                 505                 510

 Met Thr Glu Glu Glu Lys Ala Ala Gln Lys Ala Lys Pro Val Ala
                 515                 520                 525

 Thr Ala Pro Ile Pro Gly Thr Pro Trp Cys Val Val Trp Thr Gly
                 530                 535                 540

 Asp Glu Arg Val Phe Phe Tyr Asn Pro Thr Thr Arg Leu Ser Met
                 545                 550                 555

 Trp Asp Arg Pro Asp Asp Leu Ile Gly Arg Ala Asp Val Asp Lys
                 560                 565                 570

 Ile Ile Gln Glu Pro Pro His Lys Lys Gly Met Glu Glu Leu Lys
                 575                 580                 585

 Lys Leu Arg His Pro Thr Pro Thr Met Leu Ser Ile Gln Lys Trp
                 590                 595                 600

 Gln Phe Ser Met Ser Ala Ile Lys Glu Glu Gln Glu Leu Met Glu
                 605                 610                 615

 Glu Ile Asn Glu Asp Glu Pro Val Lys Ala Lys Lys Arg Lys Arg
                 620                 625                 630

 Asp Asp Asn Lys Asp Ile Asp Ser Glu Lys Glu Ala Ala Met Glu
                 635                 640                 645

 Ala Glu Ile Lys Ala Ala Arg Glu Arg Ala Ile Val Pro Leu Glu
                 650                 655                 660

 Ala Arg Met Lys Gln Phe Lys Asp Met Leu Leu Glu Arg Gly Val
                 665                 670                 675

 Ser Ala Phe Ser Thr Trp Glu Lys Glu Leu His Lys Ile Val Phe
                 680                 685                 690

 Asp Pro Arg Tyr Leu Leu Leu Asn Pro Lys Glu Arg Lys Gln Val
                 695                 700                 705

 Phe Asp Gln Tyr Val Lys Thr Arg Ala Glu Glu Glu Arg Arg Glu
                 710                 715                 720

 Lys Lys Asn Lys Ile Met Gln Ala Lys Glu Asp Phe Lys Lys Met
                 725                 730                 735

 Met Glu Glu Ala Lys Phe Asn Pro Arg Ala Thr Phe Ser Glu Phe
                 740                 745                 750

 Ala Ala Lys His Ala Lys Asp Ser Arg Phe Lys Ala Ile Glu Lys
                 755                 760                 765

 Met Lys Asp Arg Glu Ala Leu Phe Asn Glu Phe Val Ala Ala Ala
                 770                 775                 780

 Arg Lys Lys Glu Lys Glu Asp Ser Lys Thr Arg Gly Glu Lys Ile
                 785                 790                 795

 Lys Ser Asp Phe Phe Glu Leu Leu Ser Asn His His Leu Asp Ser
                 800                 805                 810

 Gln Ser Arg Trp Ser Lys Val Lys Asp Lys Val Glu Ser Asp Pro
                 815                 820                 825

 Arg Tyr Lys Ala Val Asp Ser Ser Ser Met Arg Glu Asp Leu Phe
                 830                 835                 840

 Lys Gln Tyr Ile Glu Lys Ile Ala Lys Asn Leu Asp Ser Glu Lys
                 845                 850                 855

 Glu Lys Glu Leu Glu Arg Gln Ala Arg Ile Glu Ala Ser Leu Arg
                 860                 865                 870

 Glu Arg Glu Arg Glu Val Gln Lys Ala Arg Ser Glu Gln Thr Lys
                 875                 880                 885

 Glu Ile Asp Arg Glu Arg Glu Gln His Lys Arg Glu Glu Ala Ile
                 890                 895                 900

 Gln Asn Phe Lys Ala Leu Leu Ser Asp Met Val Arg Ser Ser Asp
                 905                 910                 915

 Val Ser Trp Ser Asp Thr Arg Arg Thr Leu Arg Lys Asp His Arg
                 920                 925                 930

 Trp Glu Ser Gly Ser Leu Leu Glu Arg Glu Glu Lys Glu Lys Leu
                 935                 940                 945

 Phe Asn Glu His Ile Glu Ala Leu Thr Lys Lys Lys Arg Glu His
                 950                 955                 960

 Phe Arg Gln Leu Leu Asp Glu Thr Ser Ala Ile Thr Leu Thr Ser
                 965                 970                 975

 Thr Trp Lys Glu Val Lys Lys Ile Ile Lys Glu Asp Pro Arg Cys
                 980                 985                 990

 Ile Lys Phe Ser Ser Ser Asp Arg Lys Lys Gln Arg Glu Phe Glu
                 995                1000                1005

 Glu Tyr Ile Arg Asp Lys Tyr Ile Thr Ala Lys Ala Asp Phe Arg
                1010                1015                1020

 Thr Leu Leu Lys Glu Thr Lys Phe Ile Thr Tyr Arg Ser Lys Lys
                1025                1030                1035

 Leu Ile Gln Glu Ser Asp Gln His Leu Lys Asp Val Glu Lys Ile
                1040                1045                1050

 Leu Gln Asn Asp Lys Arg Tyr Leu Val Leu Asp Cys Val Pro Glu
                1055                1060                1065

 Glu Arg Arg Lys Leu Ile Val Ala Tyr Val Asp Asp Leu Asp Arg
                1070                1075                1080

 Arg Gly Pro Pro Pro Pro Pro Thr Ala Ser Glu Pro Thr Arg Arg
                1085                1090                1095

 Ser Thr Lys


<210> 5741
<211> 2010
<212> DNA
<213> Homo sapien

<400> 5741
 atgtggctct tcttcgggat cactggattg ctgacggcag ccctctcagg 50

 tcatccatct ccagccccac ctgaccagct caacaccagc agtgcagaga 100

 gtgagctctg ggagccaggg gagcggcttc cggtccgtct gacaaacggg 150

 agcagcagct gcagcgggac ggtggaggtg cggctcgagg cgtcctggga 200

 gcccgcgtgc ggggcgctct gggacagccg cgccgccgag gccgtgtgcc 250

 gagcactggg ctgcggcggg gcggaggccg cctctcagct cgccccgccg 300

 acccctgagc tgccgccccc gcctgcagcc gggaacacca gcgtagcagc 350

 taatgccact ctggccgggg cgcccgccct cctgtgcagc ggcgccgagt 400

 ggcggctctg cgaggtggtg gagcacgcgt gccgcagcga cgggaggcgg 450

 gcccgtgtca cctgtgcaga gaaccgcgcg ctgcgcctgg tggacggtgg 500

 cggcgcctgc gccggccgcg tggagatgct ggagcatggc gagtggggat 550

 cagtgtgcga tgacacttgg gacctggagg acgcccacgt ggtgtgcagg 600

 caactgggct gcggctgggc agtccaggcc ctgcccggct tgcacttcac 650

 gcccggccgc gggcctatcc accgggacca ggtgaactgc tcgggggccg 700

 aagcttacct gtgggactgc ccggggctgc caggacagca ctactgcggc 750

 cacaaagagg acgcgggcgt ggtgtgctca gagcaccagt cctggcgcct 800

 gacagggggc gctgaccgct gcgaggggca ggtggaggta cacttccgag 850

 gggtctggaa cacagtgtgt gacagtgagt ggtacccatc ggaggccaag 900

 gtgctctgcc agtccttggg ctgtggaact gcggttgaga ggcccaaggg 950

 gctgccccac tccttgtccg gcaggatgta ctactcatgc aatggggagg 1000

 agctcaccct ctccaactgc tcctggcggt tcaacaactc caacctctgc 1050

 agccagtcgc tggcagccag ggtcctctgc tcagcttccc ggagtttgca 1100

 caatctgtcc actcccgaag tccctgcaag tgttcagaca gtcactatag 1150

 aatcttctgt gacagtgaaa atagagaaca aggaatctcg ggagctaatg 1200

 ctcctcatcc cctccatcgt tctgggaatt ctcctccttg gctccctcat 1250

 cttcatagcc ttcatcctct tgagaattaa aggaaaatat gccctccccg 1300

 taatggtgaa ccaccagcac ctacccacca ccatcccggc agggagcaat 1350

 agctatcaac cggtccccat caccatcccc aaagaagttt tcatgctgcc 1400

 catccaggtc caggccccgc cccctgagga ctcagactct ggctcggact 1450

 cagactatga gcactatgac ttcagcgccc agcctcctgt ggccctgacc 1500

 accttctaca attcccagcg gcatcgggtc acagatgagg aggtccagca 1550

 aagcaggttc cagatgccac ccttggagga aggacttgaa gagttgcatg 1600

 cctcccacat cccaactgcc aaccctggac actgcattac agacccgcca 1650

 tccctgggcc ctcagtatca cccgaggagc aacagtgagt cgagcacctc 1700

 ttcgggggag gattactgca atagtcccaa aagcaagctg cctccatgga 1750

 acccccaggt gttttcttca gagaggagtt ccttcctgga gcagccccca 1800

 aacttggagc tggccggcac ccagccagcc ttttcagcag ggcccccggc 1850

 tgatgacagc tccagcacct catccgggga gtggtaccag aacttccagc 1900

 caccacccca gcccccttcg gaggagcagt ttggctgtcc agggtccccc 1950

 agccctcagc ctgactccac cgacaacgat gactacgatg acatcagcgc 2000

 agcctaggcc 2010

<210> 5742
<211> 668
<212> PRT
<213> Homo sapien

<400> 5742
 Met Trp Leu Phe Phe Gly Ile Thr Gly Leu Leu Thr Ala Ala Leu
   1               5                  10                  15

 Ser Gly His Pro Ser Pro Ala Pro Pro Asp Gln Leu Asn Thr Ser
                  20                  25                  30

 Ser Ala Glu Ser Glu Leu Trp Glu Pro Gly Glu Arg Leu Pro Val
                  35                  40                  45

 Arg Leu Thr Asn Gly Ser Ser Ser Cys Ser Gly Thr Val Glu Val
                  50                  55                  60

 Arg Leu Glu Ala Ser Trp Glu Pro Ala Cys Gly Ala Leu Trp Asp
                  65                  70                  75

 Ser Arg Ala Ala Glu Ala Val Cys Arg Ala Leu Gly Cys Gly Gly
                  80                  85                  90

 Ala Glu Ala Ala Ser Gln Leu Ala Pro Pro Thr Pro Glu Leu Pro
                  95                 100                 105

 Pro Pro Pro Ala Ala Gly Asn Thr Ser Val Ala Ala Asn Ala Thr
                 110                 115                 120

 Leu Ala Gly Ala Pro Ala Leu Leu Cys Ser Gly Ala Glu Trp Arg
                 125                 130                 135

 Leu Cys Glu Val Val Glu His Ala Cys Arg Ser Asp Gly Arg Arg
                 140                 145                 150

 Ala Arg Val Thr Cys Ala Glu Asn Arg Ala Leu Arg Leu Val Asp
                 155                 160                 165

 Gly Gly Gly Ala Cys Ala Gly Arg Val Glu Met Leu Glu His Gly
                 170                 175                 180

 Glu Trp Gly Ser Val Cys Asp Asp Thr Trp Asp Leu Glu Asp Ala
                 185                 190                 195

 His Val Val Cys Arg Gln Leu Gly Cys Gly Trp Ala Val Gln Ala
                 200                 205                 210

 Leu Pro Gly Leu His Phe Thr Pro Gly Arg Gly Pro Ile His Arg
                 215                 220                 225

 Asp Gln Val Asn Cys Ser Gly Ala Glu Ala Tyr Leu Trp Asp Cys
                 230                 235                 240

 Pro Gly Leu Pro Gly Gln His Tyr Cys Gly His Lys Glu Asp Ala
                 245                 250                 255

 Gly Val Val Cys Ser Glu His Gln Ser Trp Arg Leu Thr Gly Gly
                 260                 265                 270

 Ala Asp Arg Cys Glu Gly Gln Val Glu Val His Phe Arg Gly Val
                 275                 280                 285

 Trp Asn Thr Val Cys Asp Ser Glu Trp Tyr Pro Ser Glu Ala Lys
                 290                 295                 300

 Val Leu Cys Gln Ser Leu Gly Cys Gly Thr Ala Val Glu Arg Pro
                 305                 310                 315

 Lys Gly Leu Pro His Ser Leu Ser Gly Arg Met Tyr Tyr Ser Cys
                 320                 325                 330

 Asn Gly Glu Glu Leu Thr Leu Ser Asn Cys Ser Trp Arg Phe Asn
                 335                 340                 345

 Asn Ser Asn Leu Cys Ser Gln Ser Leu Ala Ala Arg Val Leu Cys
                 350                 355                 360

 Ser Ala Ser Arg Ser Leu His Asn Leu Ser Thr Pro Glu Val Pro
                 365                 370                 375

 Ala Ser Val Gln Thr Val Thr Ile Glu Ser Ser Val Thr Val Lys
                 380                 385                 390

 Ile Glu Asn Lys Glu Ser Arg Glu Leu Met Leu Leu Ile Pro Ser
                 395                 400                 405

 Ile Val Leu Gly Ile Leu Leu Leu Gly Ser Leu Ile Phe Ile Ala
                 410                 415                 420

 Phe Ile Leu Leu Arg Ile Lys Gly Lys Tyr Ala Leu Pro Val Met
                 425                 430                 435

 Val Asn His Gln His Leu Pro Thr Thr Ile Pro Ala Gly Ser Asn
                 440                 445                 450

 Ser Tyr Gln Pro Val Pro Ile Thr Ile Pro Lys Glu Val Phe Met
                 455                 460                 465

 Leu Pro Ile Gln Val Gln Ala Pro Pro Pro Glu Asp Ser Asp Ser
                 470                 475                 480

 Gly Ser Asp Ser Asp Tyr Glu His Tyr Asp Phe Ser Ala Gln Pro
                 485                 490                 495

 Pro Val Ala Leu Thr Thr Phe Tyr Asn Ser Gln Arg His Arg Val
                 500                 505                 510

 Thr Asp Glu Glu Val Gln Gln Ser Arg Phe Gln Met Pro Pro Leu
                 515                 520                 525

 Glu Glu Gly Leu Glu Glu Leu His Ala Ser His Ile Pro Thr Ala
                 530                 535                 540

 Asn Pro Gly His Cys Ile Thr Asp Pro Pro Ser Leu Gly Pro Gln
                 545                 550                 555

 Tyr His Pro Arg Ser Asn Ser Glu Ser Ser Thr Ser Ser Gly Glu
                 560                 565                 570

 Asp Tyr Cys Asn Ser Pro Lys Ser Lys Leu Pro Pro Trp Asn Pro
                 575                 580                 585

 Gln Val Phe Ser Ser Glu Arg Ser Ser Phe Leu Glu Gln Pro Pro
                 590                 595                 600

 Asn Leu Glu Leu Ala Gly Thr Gln Pro Ala Phe Ser Ala Gly Pro
                 605                 610                 615

 Pro Ala Asp Asp Ser Ser Ser Thr Ser Ser Gly Glu Trp Tyr Gln
                 620                 625                 630

 Asn Phe Gln Pro Pro Pro Gln Pro Pro Ser Glu Glu Gln Phe Gly
                 635                 640                 645

 Cys Pro Gly Ser Pro Ser Pro Gln Pro Asp Ser Thr Asp Asn Asp
                 650                 655                 660

 Asp Tyr Asp Asp Ile Ser Ala Ala
                 665

<210> 5743
<211> 2126
<212> DNA
<213> Homo sapien

<400> 5743
 gctctgtcag taacacatgt gtaagagccg cggagggagc gagcgagccg 50

 gctagaggcc agcgccgccg ccgccgccgc ctccgagccg ggcagcaaca 100

 gccccggcag cggcgcaggc tccagcgcgc cgggcccggc cggccgcagc 150

 ccccgacgcc tgggtgcgcc tgcctgccgg cctccgcacc gtccgccgcc 200

 gctcccgggg ctgttgtgtc tgcgactgct cccggccgga ggtgcaggga 250

 gctcagccga gccgccgctg ccatcccgga gcgagcaagc gagcgagcgc 300

 gcgggaggga ggaaggcggc ggcggaggag gaggaggagc gggaggagcg 350

 cgggcggggg cgggggccgc cgggcggggg aatatacaaa gtgaagccac 400

 attgccaaac ttgcagcagc gattgcagca gttgctgccg ctgcgccgcg 450

 cctgaagccg cgccgcgcgg gccgagggct cctgcagctg ctcgcgcgca 500

 gtcggaggcg gagaaggacg aagactgaga ctgacacttc tgctcccggc 550

 cgcccggcac ttacgcgggg gccccccaac ccgccccaga gcaacgcgat 600

 ttaaaaaaaa aaaaaaagcc gcccttagcc ccctcctctc ctttcctgct 650

 tctgcgagaa ctccctccct ccctccagct ccgccagccc aggcgcccct 700

 tccctggaag ccgagcggct tcgctcgcat ttcaccgccg ccgcctctcg 750

 caatattgca atatagggga aaagcagacc atggtgaatc cgggcagcag 800

 ctcgcagccg cccccggtga cggccggctc cctctcctgg aagcggtgcg 850

 caggctgcgg gggcaagatt gcggaccgct ttctgctcta tgccatggac 900

 agctattggc acagccggtg cctcaagtgc tcctgctgcc aggcgcagct 950

 gggcgacatc ggcacgtcct gttacaccaa aagtggcatg atcctttgca 1000

 gaaatgacta cattaggtta tttggaaata gcggtgcttg cagcgcttgc 1050

 ggacagtcga ttcctgcgag tgaactcgtc atgagggcgc aaggcaatgt 1100

 gtatcatctt aagtgtttta catgctctac ctgccggaat cgcctggtcc 1150

 cgggagatcg gtttcactac atcaatggca gtttattttg tgaacatgat 1200

 agacctacag ctctcatcaa tggccatttg aattcacttc agagcaatcc 1250

 actactgcca gaccagaagg tctgctaaaa ggtcagagta atgcagaatg 1300

 cgtgccttca tctcagattt gttcatcaca ggtggatccc atgtgtcttc 1350

 agtagacaag tcacctttgt agctagcacc agtgccagct ccatgccatt 1400

 gcaccttctt tagtcttgat tgcccttccc gcatttattg gtgtattaaa 1450

 atgactgaat atgaacatta aggactccat gaacctgggc taatgggaga 1500

 ctgtagagaa aatgaaaaaa gatccaccag aggacatctt ggggaggggg 1550

 agggagctgg gggggaggga aatgactaat gaagctaatt aaaagaagca 1600

 ttcaaatctg ctttctaccc tcattaacaa ttagcagggc actggccaga 1650

 gtttgtaccc tgtgttttac cttaacaaca ttctatttgc tctttgtata 1700

 tttaagtgtt gtaaggaaac gtgtttcaat caaaactgac catgagataa 1750

 aggaaagaga tgtggctttt gtgatattct atcacaaaca cttattgtat 1800

 ctctgtaaaa tacaatgtat gtatgcatgt aagtgttttt gtcctaatgt 1850

 tgctactccc atggcaaaga aaaaaaaaag aatgaaaaaa agaaaaaaaa 1900

 tttggaaaaa aaaatcaggc tcatagcagc tactgtgtag aaaattcccc 1950

 ctacttctaa tttgctgaat gaagaaaaaa aaaaatcttt tatttgtgat 2000

 attttcagag acatttgctc tagtatggtg tatttaaata ataaaaactt 2050

 aaaagaaaaa ataaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2100

 aaaaaaaaaa aaaaaaaaaa aaaaaa 2126

<210> 5744
<211> 165
<212> PRT
<213> Homo sapien

<400> 5744
 Met Val Asn Pro Gly Ser Ser Ser Gln Pro Pro Pro Val Thr Ala
   1               5                  10                  15

 Gly Ser Leu Ser Trp Lys Arg Cys Ala Gly Cys Gly Gly Lys Ile
                  20                  25                  30

 Ala Asp Arg Phe Leu Leu Tyr Ala Met Asp Ser Tyr Trp His Ser
                  35                  40                  45

 Arg Cys Leu Lys Cys Ser Cys Cys Gln Ala Gln Leu Gly Asp Ile
                  50                  55                  60

 Gly Thr Ser Cys Tyr Thr Lys Ser Gly Met Ile Leu Cys Arg Asn
                  65                  70                  75

 Asp Tyr Ile Arg Leu Phe Gly Asn Ser Gly Ala Cys Ser Ala Cys
                  80                  85                  90

 Gly Gln Ser Ile Pro Ala Ser Glu Leu Val Met Arg Ala Gln Gly
                  95                 100                 105

 Asn Val Tyr His Leu Lys Cys Phe Thr Cys Ser Thr Cys Arg Asn
                 110                 115                 120

 Arg Leu Val Pro Gly Asp Arg Phe His Tyr Ile Asn Gly Ser Leu
                 125                 130                 135

 Phe Cys Glu His Asp Arg Pro Thr Ala Leu Ile Asn Gly His Leu
                 140                 145                 150

 Asn Ser Leu Gln Ser Asn Pro Leu Leu Pro Asp Gln Lys Val Cys
                 155                 160                 165

<210> 5745
<211> 2697
<212> DNA
<213> Homo sapien

<400> 5745
 acgcgggcac gcacacacgg aagcacgcct ccacttaact cgcgccgccg 50

 cggcagctcg agtccaccag cagcgccgtc cgcttgaccg agatgctgcg 100

 ggcctgtcag ttatcgggtg tgaccgccgc cgcccagagt tgtctctgtg 150

 ggaagtttgt cctccgtcca ttgcgaccat gccgcagata ctctacttca 200

 ggcagctctg ggttgactac tggcaaaatt gctggagctg gccttttgtt 250

 tgttggtgga ggtattggtg gcactatcct atatgccaaa tgggattccc 300

 atttccggga aagtgtagag aaaaccatac cttactcaga caaactcttc 350

 gagatggttc ttggtcctgc agcttataat gttccattgc caaagaaatc 400

 gattcagtcg ggtccactaa aaatctctag tgtatcagaa gtaatgaaag 450

 aatctaaaca gtctgcctca caactccaaa aacaaaaggg agatactcca 500

 gcttcagcaa cagcacctac agaagcggct caaattattt ctgcagcagg 550

 tgataccctg tcggtcccag cccctgcagt tcagcctgag gaatctttaa 600

 aaactgatca ccctgaaatt ggtgaaggaa aacccacacc tgcactttca 650

 gaagaagcat cctcatcttc tataagggag cgaccacctg aagaagttgc 700

 agctcgcctt gcacaacagg aaaaacaaga acaagttaaa attgagtctc 750

 tagccaagag cttagaagat gctctgaggc aaactgcaag tgtcactctg 800

 caggctattg cagctcagaa tgctgcggtc caggctgtca atgcacactc 850

 caacatattg aaagccgcca tggacaattc tgagattgca ggcgagaaga 900

 aatctgctca gtggcgcaca gtggagggtg cattgaagga acgcagaaag 950

 gcagtagatg aagctgccga tgcccttctc aaagccaaag aagagttaga 1000

 gaagatgaaa agtgtgattg aaaatgcaaa gaaaaaagag gttgctgggg 1050

 ccaagcctca tataactgct gcagagggta aacttcacaa catgatagtt 1100

 gatctggata atgtggtcaa aaaggtccaa gcagctcagt ctgaggctaa 1150

 ggttgtatct cagtatcatg agctggtggt ccaagctcgg gatgacttta 1200

 aacgagagct ggacagtatt actccagaag tccttcctgg atggaaagga 1250

 atgagtgttt cagacttagc tgacaagctc tctactgatg atctgaactc 1300

 cctcattgct catgcacatc gtcgtattga tcagctgaac agagagctgg 1350

 cagaacagaa ggccaccgaa aagcagcaca tcacgttagc cttggagaaa 1400

 caaaagctgg aagaaaagcg ggcatttgac tctgcagtag caaaagcatt 1450

 agaacatcac agaagtgaaa tacaggctga acaggacaga aagatagaag 1500

 aagtcagaga tgccatggaa aatgaaatga gaacccagct tcgccgacag 1550

 gcagctgccc acactgatca cttgcgagat gtccttaggg tacaagaaca 1600

 ggaattgaag tctgaatttg agcagaacct gtctgagaaa ctctctgaac 1650

 aagaattaca atttcgtcgt ctcagtcaag agcaagttga caactttact 1700

 ctggatataa atactgccta tgccagactc agaggaatcg aacaggctgt 1750

 tcagagccat gcagttgctg aagaggaagc cagaaaagcc caccaactct 1800

 ggctttcagt ggaggcatta aagtacagca tgaagacctc atctgcagaa 1850

 acacctacta tcccgctggg tagtgcagtt gaggccatca aagccaactg 1900

 ttctgataat gaattcaccc aagctttaac cgcagctatc cctccagagt 1950

 ccctgacccg tggggtgtac agtgaagaga cccttagagc ccgtttctat 2000

 gctgttcaaa aactggcccg aagggtagca atgattgatg aaaccagaaa 2050

 tagcttgtac cagtacttcc tctcctacct acagtccctg ctcctattcc 2100

 cacctcagca actgaagccg cccccagagc tctgccctga ggatataaac 2150

 acatttaaat tactgtcata tgcttcctat tgcattgagc atggtgatct 2200

 ggagctagca gcaaagtttg tcaatcagct gaagggggaa tccagacgag 2250

 tggcacagga ctggctgaag gaagcccgaa tgaccctaga aacgaaacag 2300

 atagtggaaa tcctgacagc atatgccagc gccgtaggaa taggaaccac 2350

 tcaggtgcag ccagagtgag gtttaggaag attttcataa agtcatattt 2400

 catgtcaaag gaaatcagca gtgatagatg aagggttcgc agcgagagtc 2450

 ccggacttgt ctagaaatga gcaggtttac aagtactgtt ctaaatgtta 2500

 acacctgttg catttatatt ctttccattt gctatcatgt cagtgaacgc 2550

 caggagtgct ttctttgcaa cttgtgtaac attttctgtt ttttcaggtt 2600

 ttactgatga ggcttgtgag gccaatcaaa ataatgtttg tgatctctac 2650

 tactgttgat tttgccctcg gagcaaactg aataaagcaa caagatg 2697

<210> 5746
<211> 758
<212> PRT
<213> Homo sapien

<400> 5746
 Met Leu Arg Ala Cys Gln Leu Ser Gly Val Thr Ala Ala Ala Gln
   1               5                  10                  15

 Ser Cys Leu Cys Gly Lys Phe Val Leu Arg Pro Leu Arg Pro Cys
                  20                  25                  30

 Arg Arg Tyr Ser Thr Ser Gly Ser Ser Gly Leu Thr Thr Gly Lys
                  35                  40                  45

 Ile Ala Gly Ala Gly Leu Leu Phe Val Gly Gly Gly Ile Gly Gly
                  50                  55                  60

 Thr Ile Leu Tyr Ala Lys Trp Asp Ser His Phe Arg Glu Ser Val
                  65                  70                  75

 Glu Lys Thr Ile Pro Tyr Ser Asp Lys Leu Phe Glu Met Val Leu
                  80                  85                  90

 Gly Pro Ala Ala Tyr Asn Val Pro Leu Pro Lys Lys Ser Ile Gln
                  95                 100                 105

 Ser Gly Pro Leu Lys Ile Ser Ser Val Ser Glu Val Met Lys Glu
                 110                 115                 120

 Ser Lys Gln Ser Ala Ser Gln Leu Gln Lys Gln Lys Gly Asp Thr
                 125                 130                 135

 Pro Ala Ser Ala Thr Ala Pro Thr Glu Ala Ala Gln Ile Ile Ser
                 140                 145                 150

 Ala Ala Gly Asp Thr Leu Ser Val Pro Ala Pro Ala Val Gln Pro
                 155                 160                 165

 Glu Glu Ser Leu Lys Thr Asp His Pro Glu Ile Gly Glu Gly Lys
                 170                 175                 180

 Pro Thr Pro Ala Leu Ser Glu Glu Ala Ser Ser Ser Ser Ile Arg
                 185                 190                 195

 Glu Arg Pro Pro Glu Glu Val Ala Ala Arg Leu Ala Gln Gln Glu
                 200                 205                 210

 Lys Gln Glu Gln Val Lys Ile Glu Ser Leu Ala Lys Ser Leu Glu
                 215                 220                 225

 Asp Ala Leu Arg Gln Thr Ala Ser Val Thr Leu Gln Ala Ile Ala
                 230                 235                 240

 Ala Gln Asn Ala Ala Val Gln Ala Val Asn Ala His Ser Asn Ile
                 245                 250                 255

 Leu Lys Ala Ala Met Asp Asn Ser Glu Ile Ala Gly Glu Lys Lys
                 260                 265                 270

 Ser Ala Gln Trp Arg Thr Val Glu Gly Ala Leu Lys Glu Arg Arg
                 275                 280                 285

 Lys Ala Val Asp Glu Ala Ala Asp Ala Leu Leu Lys Ala Lys Glu
                 290                 295                 300

 Glu Leu Glu Lys Met Lys Ser Val Ile Glu Asn Ala Lys Lys Lys
                 305                 310                 315

 Glu Val Ala Gly Ala Lys Pro His Ile Thr Ala Ala Glu Gly Lys
                 320                 325                 330

 Leu His Asn Met Ile Val Asp Leu Asp Asn Val Val Lys Lys Val
                 335                 340                 345

 Gln Ala Ala Gln Ser Glu Ala Lys Val Val Ser Gln Tyr His Glu
                 350                 355                 360

 Leu Val Val Gln Ala Arg Asp Asp Phe Lys Arg Glu Leu Asp Ser
                 365                 370                 375

 Ile Thr Pro Glu Val Leu Pro Gly Trp Lys Gly Met Ser Val Ser
                 380                 385                 390

 Asp Leu Ala Asp Lys Leu Ser Thr Asp Asp Leu Asn Ser Leu Ile
                 395                 400                 405

 Ala His Ala His Arg Arg Ile Asp Gln Leu Asn Arg Glu Leu Ala
                 410                 415                 420

 Glu Gln Lys Ala Thr Glu Lys Gln His Ile Thr Leu Ala Leu Glu
                 425                 430                 435

 Lys Gln Lys Leu Glu Glu Lys Arg Ala Phe Asp Ser Ala Val Ala
                 440                 445                 450

 Lys Ala Leu Glu His His Arg Ser Glu Ile Gln Ala Glu Gln Asp
                 455                 460                 465

 Arg Lys Ile Glu Glu Val Arg Asp Ala Met Glu Asn Glu Met Arg
                 470                 475                 480

 Thr Gln Leu Arg Arg Gln Ala Ala Ala His Thr Asp His Leu Arg
                 485                 490                 495

 Asp Val Leu Arg Val Gln Glu Gln Glu Leu Lys Ser Glu Phe Glu
                 500                 505                 510

 Gln Asn Leu Ser Glu Lys Leu Ser Glu Gln Glu Leu Gln Phe Arg
                 515                 520                 525

 Arg Leu Ser Gln Glu Gln Val Asp Asn Phe Thr Leu Asp Ile Asn
                 530                 535                 540

 Thr Ala Tyr Ala Arg Leu Arg Gly Ile Glu Gln Ala Val Gln Ser
                 545                 550                 555

 His Ala Val Ala Glu Glu Glu Ala Arg Lys Ala His Gln Leu Trp
                 560                 565                 570

 Leu Ser Val Glu Ala Leu Lys Tyr Ser Met Lys Thr Ser Ser Ala
                 575                 580                 585

 Glu Thr Pro Thr Ile Pro Leu Gly Ser Ala Val Glu Ala Ile Lys
                 590                 595                 600

 Ala Asn Cys Ser Asp Asn Glu Phe Thr Gln Ala Leu Thr Ala Ala
                 605                 610                 615

 Ile Pro Pro Glu Ser Leu Thr Arg Gly Val Tyr Ser Glu Glu Thr
                 620                 625                 630

 Leu Arg Ala Arg Phe Tyr Ala Val Gln Lys Leu Ala Arg Arg Val
                 635                 640                 645

 Ala Met Ile Asp Glu Thr Arg Asn Ser Leu Tyr Gln Tyr Phe Leu
                 650                 655                 660

 Ser Tyr Leu Gln Ser Leu Leu Leu Phe Pro Pro Gln Gln Leu Lys
                 665                 670                 675

 Pro Pro Pro Glu Leu Cys Pro Glu Asp Ile Asn Thr Phe Lys Leu
                 680                 685                 690

 Leu Ser Tyr Ala Ser Tyr Cys Ile Glu His Gly Asp Leu Glu Leu
                 695                 700                 705

 Ala Ala Lys Phe Val Asn Gln Leu Lys Gly Glu Ser Arg Arg Val
                 710                 715                 720

 Ala Gln Asp Trp Leu Lys Glu Ala Arg Met Thr Leu Glu Thr Lys
                 725                 730                 735

 Gln Ile Val Glu Ile Leu Thr Ala Tyr Ala Ser Ala Val Gly Ile
                 740                 745                 750

 Gly Thr Thr Gln Val Gln Pro Glu
                 755

<210> 5747
<211> 1153
<212> DNA
<213> Homo sapien

<400> 5747
 gccgccgccg ccatgaacat tttccggctg actggggacc tgtcccacct 50

 ggcggccatc gtcatcctgc tgctgaagat ctggaagacg cgctcctgcg 100

 ccggtatttc tgggaaaagc cagcttctgt ttgcactggt cttcacaact 150

 cgttacctgg atctttttac ttcatttatt tcattgtata acacatctat 200

 gaaggttatc taccttgcct gctcctatgc cacagtgtac ctgatctacc 250

 tgaaatttaa ggcaacctac gatggaaatc atgatacctt ccgagtggag 300

 tttctggtgg tccctgtggg aggcctctca tttttagtta atcacgattt 350

 ctctcctctt gagatcctct ggaccttctc catctacctg gagtccgtgg 400

 ctatccttcc gcagctgttt atgatcagca agactgggga ggccgagacc 450

 atcaccaccc actacctgtt cttcctgggc ctctatcgtg ctttgtatct 500

 tgtcaactgg atctggcgct tctactttga gggcttcttt gacctcattg 550

 ctgtggtggc cggcgtagtc cagaccatcc tatactgtga cttcttctac 600

 ttgtacatta caaaagtact caagggaaag aagctcagtt tgccagcata 650

 agtgccaaag accatcacca gcatctgtcc ttcagggtgc tcggacagaa 700

 ttcttaccac agcaaaggca taagatgctt gatacggaaa atcagaaact 750

 taactctttt gttgcagata gtcatcagtg gctctgtaaa aacgcagagg 800

 aaaagagcca gaaggtttct gtttaatgca tcttgcctta tcttttttta 850

 ttactgtgta caaagatttt tttacacaaa gaaacttaat gctgtattaa 900

 taaattcagt gtgtagcttc aattgggata gttccaaaag tgaagatttt 950

 gtgaggaata agtgcaaatt ttttttttat tttaaaaaat tctttgaaac 1000

 tcttaagtct ttgtgtctgc aatgaaattg tactccttga cagttgatag 1050

 attatgtatt cttccatccc tcaaacttgc attccactat atttattttt 1100

 tggcaaaaga tgagctgtat ttgtttgaaa tctgagacac tatgttcaat 1150

 tgg 1153

<210> 5748
<211> 212
<212> PRT
<213> Homo sapien

<400> 5748
 Met Asn Ile Phe Arg Leu Thr Gly Asp Leu Ser His Leu Ala Ala
   1               5                  10                  15

 Ile Val Ile Leu Leu Leu Lys Ile Trp Lys Thr Arg Ser Cys Ala
                  20                  25                  30

 Gly Ile Ser Gly Lys Ser Gln Leu Leu Phe Ala Leu Val Phe Thr
                  35                  40                  45

 Thr Arg Tyr Leu Asp Leu Phe Thr Ser Phe Ile Ser Leu Tyr Asn
                  50                  55                  60

 Thr Ser Met Lys Val Ile Tyr Leu Ala Cys Ser Tyr Ala Thr Val
                  65                  70                  75

 Tyr Leu Ile Tyr Leu Lys Phe Lys Ala Thr Tyr Asp Gly Asn His
                  80                  85                  90

 Asp Thr Phe Arg Val Glu Phe Leu Val Val Pro Val Gly Gly Leu
                  95                 100                 105

 Ser Phe Leu Val Asn His Asp Phe Ser Pro Leu Glu Ile Leu Trp
                 110                 115                 120

 Thr Phe Ser Ile Tyr Leu Glu Ser Val Ala Ile Leu Pro Gln Leu
                 125                 130                 135

 Phe Met Ile Ser Lys Thr Gly Glu Ala Glu Thr Ile Thr Thr His
                 140                 145                 150

 Tyr Leu Phe Phe Leu Gly Leu Tyr Arg Ala Leu Tyr Leu Val Asn
                 155                 160                 165

 Trp Ile Trp Arg Phe Tyr Phe Glu Gly Phe Phe Asp Leu Ile Ala
                 170                 175                 180

 Val Val Ala Gly Val Val Gln Thr Ile Leu Tyr Cys Asp Phe Phe
                 185                 190                 195

 Tyr Leu Tyr Ile Thr Lys Val Leu Lys Gly Lys Lys Leu Ser Leu
                 200                 205                 210

 Pro Ala


<210> 5749
<211> 3915
<212> DNA
<213> Homo sapien

<400> 5749
 gtggggtggg gtggggctgg gggcttgtcg ccctttcagg ctccaccctt 50

 tgcggagatt ataaatagtc atgatcccag cgagacccag agatgcctgt 100

 aatggtgaga ctttggatcc ttcctgagga cgtggagaaa actttctgct 150

 gagaaggaca ttttgaaggt tttgttggct gaaaaagctg tttctggaat 200

 cacccctaga tctttcttga agacttgaat tagattacag cgatggggac 250

 acagaaggtc accccagctc tgatatttgc catcacagtt gctacaatcg 300

 gctctttcca atttggctac aacactgggg tcatcaatgc tcctgagaag 350

 atcataaagg aatttatcaa taaaactttg acggacaagg gaaatgcccc 400

 accctctgag gtgctgctca cgtctctctg gtccttgtct gtggccatat 450

 tttccgtcgg gggtatgatc ggctcctttt ccgtcggact cttcgtcaac 500

 cgctttggca ggcgcaattc aatgctgatt gtcaacctgt tggctgtcac 550

 tggtggctgc tttatgggac tgtgtaaagt agctaagtcg gttgaaatgc 600

 tgatcctggg tcgcttggtt attggcctct tctgcggact ctgcacaggt 650

 tttgtgccca tgtacattgg agagatctcg cctactgccc tgcggggtgc 700

 ctttggcact ctcaaccagc tgggcatcgt tgttggaatt ctggtggccc 750

 agatctttgg tctggaattc atccttgggt ctgaagagct atggccgctg 800

 ctactgggtt ttaccatcct tcctgctatc ctacaaagtg cagcccttcc 850

 attttgccct gaaagtccca gatttttgct cattaacaga aaagaagagg 900

 agaatgctaa gcagatcctc cagcggttgt ggggcaccca ggatgtatcc 950

 caagacatcc aggagatgaa agatgagagt gcaaggatgt cacaagaaaa 1000

 gcaagtcacc gtgctagagc tctttagagt gtccagctac cgacagccca 1050

 tcatcatttc cattgtgctc cagctctctc agcagctctc tgggatcaat 1100

 gctgtgttct attactcaac aggaatcttc aaggatgcag gtgttcaaga 1150

 gcccatctat gccaccatcg gcgcgggtgt ggttaatact atcttcactg 1200

 tagtttctct atttctggtg gaaagggcag gaagaaggac tctgcatatg 1250

 ataggccttg gagggatggc tttttgttcc acgctcatga ctgtttcttt 1300

 gttattaaag gataactata atgggatgag ctttgtctgt attggggcta 1350

 tcttggtctt tgtagccttc tttgaaattg gaccaggccc cattccctgg 1400

 tttattgtgg ccgaactctt cagccagggc ccccgcccag ctgcgatggc 1450

 agtggccggc tgctccaact ggacctccaa cttcctagtc ggattgctct 1500

 tcccctccgc tgctcactat ttaggagcct acgtttttat tatcttcacc 1550

 ggcttcctca ttaccttctt ggcttttacc ttcttcaaag tccctgagac 1600

 ccgtggcagg acttttgagg atatcacacg ggcctttgaa gggcaggcac 1650

 acggtgcaga tagatctgga aaggacggcg tcatggagat gaacagcatc 1700

 gagcctgcta aggagaccac caccaatgtc taagtcgtgc ctccttccac 1750

 ctccctcccg gcatgggaaa gccacctctc cctcaacaag ggagagacct 1800

 catcaggatg aacccaggac gcttctgaat gctgctactt aattcctttc 1850

 tcatcccacg cactccatga gcaccccaag gctgcggttt gttggatctt 1900

 caatggcttt ttaaatttta tttcctggac atcctcttct gcttaggaga 1950

 gaccgagtga acctaccttc atttcaggag ggattggccg cttggcacat 2000

 gacaactttg ccagcttttc ctcccttggg ttctgatatt gccgcactag 2050

 gggatatagg agaggaaaag taaggtgcag ttcccccaac ctcagactta 2100

 ccaggaagca gatacatatg agtgtggaag ccggagggtg tttatgtaag 2150

 agcaccttcc tcacttccat acagctctac gtggcaaatt aacttgagtt 2200

 ttatttattt tatcctctgg tttaattaca taattttttt ttttttactt 2250

 taagtttcag gatacatgtg ccgaatgtgc aggtttgtta cataggtata 2300

 tatatgccat gatggaaata tttatttttt taagcgtaat tttgccaaat 2350

 aataaaaaca gaaggaaatt gagattagag ggaggtgttt aaagagaggt 2400

 tatagagtag aagatttgat gctggagagg ttaaggtgca ataagaattt 2450

 agggagaaat gttgttcatt attggagggt aaatgatgtg gtgcctgagg 2500

 tctgtacgtt acctcttaac aatttctgtc cttcagatgg aaactcttta 2550

 acttctcgta aaagtcatat acctatataa taaagctact gatttccttg 2600

 gagctttttt ctttaagata atagtttaca tgtagtagta cttgaaatct 2650

 aggattatta actaatatgg gcattgtagt taatgatggt tgatgggttc 2700

 taattttgga tggagtccag ggaagagaaa gtgatttcta gaaagcctgt 2750

 tcccctcact ggatgaaata actccttctt gtagtagtct cattactttt 2800

 gaagtaatcc cgccacctat ctcgtgggag agccatccaa ataagaaacc 2850

 taaaataatt ggttcttggt agagattcat tatttttcca ctttgttctt 2900

 taggagattt taggtgttga ttttctgttg tattttaact cataccttta 2950

 aaggaattcc ccaaagaatg tttatagcaa acttggaatt tgtaacctca 3000

 gctctgggag aggatttttt tctgagcgat tattatctaa agtgtgttgt 3050

 tgctttaggc tcacggcacg cttgcgtatg tctgttacca tgtcactgtg 3100

 gtcctatgcc gaatgccctc aggggacttg aatctttcca ataaaccagg 3150

 tttagacagt atgagtcaat gtgcagtgta gcccacactt gagaggatga 3200

 atgtatgtgc actgtcactt tgctctgggt ggaagtacgt tattgttgac 3250

 ttattttctc tgtgtttgtt cctacagccc ctttttcata tgttgctcag 3300

 tctccctttc ccttcttggt gcttacacat ctcagaccct ttagccaaac 3350

 ccttgtcagt gacagtattt tggttcttag ttctcactgt tccctctgct 3400

 cctggagcct ttgaataaaa atgcacgtag ctgaggccgg atgcggtggc 3450

 tcacgcctgt aatcccagca ctttgggagg cctaggcggg cggtcagggg 3500

 ttcgagacca gtctggccaa catcgtgaaa ccctgtctct actaaaaatg 3550

 caaaaattag ccgggcgtgg tggcgggcgc ctgtaatccc agctacttgg 3600

 gaagctgagg cgggagaatc atgtgaaccc gggacgcagg ggttgcagtg 3650

 agcggagatc gcatcattgc actctagcct gggccacagg gcgagactcc 3700

 gtctcaaaaa aaaaaaaatg cacatagcta tcgagtgtgc tttagcttga 3750

 aaaggtgacc ttgcaacttc atgtcaactt tctggctcct caaacagtag 3800

 gttggcagta aggcagggtc ccatttctca ctgagaagat tgtgaatatt 3850

 tccatatgga ttttctattg ttactctggt tctttgtttt aaaataaaaa 3900

 ttctgaatgt acacg 3915

<210> 5750
<211> 496
<212> PRT
<213> Homo sapien

<400> 5750
 Met Gly Thr Gln Lys Val Thr Pro Ala Leu Ile Phe Ala Ile Thr
   1               5                  10                  15

 Val Ala Thr Ile Gly Ser Phe Gln Phe Gly Tyr Asn Thr Gly Val
                  20                  25                  30

 Ile Asn Ala Pro Glu Lys Ile Ile Lys Glu Phe Ile Asn Lys Thr
                  35                  40                  45

 Leu Thr Asp Lys Gly Asn Ala Pro Pro Ser Glu Val Leu Leu Thr
                  50                  55                  60

 Ser Leu Trp Ser Leu Ser Val Ala Ile Phe Ser Val Gly Gly Met
                  65                  70                  75

 Ile Gly Ser Phe Ser Val Gly Leu Phe Val Asn Arg Phe Gly Arg
                  80                  85                  90

 Arg Asn Ser Met Leu Ile Val Asn Leu Leu Ala Val Thr Gly Gly
                  95                 100                 105

 Cys Phe Met Gly Leu Cys Lys Val Ala Lys Ser Val Glu Met Leu
                 110                 115                 120

 Ile Leu Gly Arg Leu Val Ile Gly Leu Phe Cys Gly Leu Cys Thr
                 125                 130                 135

 Gly Phe Val Pro Met Tyr Ile Gly Glu Ile Ser Pro Thr Ala Leu
                 140                 145                 150

 Arg Gly Ala Phe Gly Thr Leu Asn Gln Leu Gly Ile Val Val Gly
                 155                 160                 165

 Ile Leu Val Ala Gln Ile Phe Gly Leu Glu Phe Ile Leu Gly Ser
                 170                 175                 180

 Glu Glu Leu Trp Pro Leu Leu Leu Gly Phe Thr Ile Leu Pro Ala
                 185                 190                 195

 Ile Leu Gln Ser Ala Ala Leu Pro Phe Cys Pro Glu Ser Pro Arg
                 200                 205                 210

 Phe Leu Leu Ile Asn Arg Lys Glu Glu Glu Asn Ala Lys Gln Ile
                 215                 220                 225

 Leu Gln Arg Leu Trp Gly Thr Gln Asp Val Ser Gln Asp Ile Gln
                 230                 235                 240

 Glu Met Lys Asp Glu Ser Ala Arg Met Ser Gln Glu Lys Gln Val
                 245                 250                 255

 Thr Val Leu Glu Leu Phe Arg Val Ser Ser Tyr Arg Gln Pro Ile
                 260                 265                 270

 Ile Ile Ser Ile Val Leu Gln Leu Ser Gln Gln Leu Ser Gly Ile
                 275                 280                 285

 Asn Ala Val Phe Tyr Tyr Ser Thr Gly Ile Phe Lys Asp Ala Gly
                 290                 295                 300

 Val Gln Glu Pro Ile Tyr Ala Thr Ile Gly Ala Gly Val Val Asn
                 305                 310                 315

 Thr Ile Phe Thr Val Val Ser Leu Phe Leu Val Glu Arg Ala Gly
                 320                 325                 330

 Arg Arg Thr Leu His Met Ile Gly Leu Gly Gly Met Ala Phe Cys
                 335                 340                 345

 Ser Thr Leu Met Thr Val Ser Leu Leu Leu Lys Asp Asn Tyr Asn
                 350                 355                 360

 Gly Met Ser Phe Val Cys Ile Gly Ala Ile Leu Val Phe Val Ala
                 365                 370                 375

 Phe Phe Glu Ile Gly Pro Gly Pro Ile Pro Trp Phe Ile Val Ala
                 380                 385                 390

 Glu Leu Phe Ser Gln Gly Pro Arg Pro Ala Ala Met Ala Val Ala
                 395                 400                 405

 Gly Cys Ser Asn Trp Thr Ser Asn Phe Leu Val Gly Leu Leu Phe
                 410                 415                 420

 Pro Ser Ala Ala His Tyr Leu Gly Ala Tyr Val Phe Ile Ile Phe
                 425                 430                 435

 Thr Gly Phe Leu Ile Thr Phe Leu Ala Phe Thr Phe Phe Lys Val
                 440                 445                 450

 Pro Glu Thr Arg Gly Arg Thr Phe Glu Asp Ile Thr Arg Ala Phe
                 455                 460                 465

 Glu Gly Gln Ala His Gly Ala Asp Arg Ser Gly Lys Asp Gly Val
                 470                 475                 480

 Met Glu Met Asn Ser Ile Glu Pro Ala Lys Glu Thr Thr Thr Asn
                 485                 490                 495

 Val


<210> 5751
<211> 1666
<212> DNA
<213> Homo sapien

<400> 5751
 atttgctttc tctttttcct ttcttccgga tgagaggcta agccataata 50

 gaaagaatgg agaattattg attgaccgtc tttattctgt gggctctgat 100

 tctccaatgg gaataccaag ggatggtttt ccatactgga acccaaaggt 150

 aaagacactc aaggacagac atttttggca gagcatagat gaaaatggca 200

 agttccctgg ctttccttct gctcaacttt catgtctccc tcctcttggt 250

 ccagctgctc actccttgct cagctcagtt ttctgtgctt ggaccctctg 300

 ggcccatcct ggccatggtg ggtgaagacg ctgatctgcc ctgtcacctg 350

 ttcccgacca tgagtgcaga gaccatggag ctgaagtggg taagttccag 400

 cctaaggcag gtggtgaacg tgtatgcaga tggaaaggaa gtggaagaca 450

 ggcagagtgc accgtatcga gggagaactt cgattctgcg ggatggcatc 500

 actgcaggga aggctgctct ccgaatacac aacgtcacag cctctgacag 550

 tggaaagtac ttgtgttatt tccaagatgg tgacttctat gaaaaagccc 600

 tggtggagct gaaggttgca gcactgggtt ctaatcttca cgtcgaagtg 650

 aagggttatg aggatggagg gatccatctg gagtgcaggt ccaccggctg 700

 gtacccccaa ccccaaatac agtggagcaa cgccaaggga gagaacatcc 750

 cagctgtgga agcacctgtg gttgcagatg gagtgggcct atatgaagta 800

 gcagcatctg tgatcatgag aggcggctcc ggggagggtg tatcctgcat 850

 catcagaaat tccctcctcg gcctggaaaa gacagccagc atttccatcg 900

 cagacccctt cttcaggagc gcccagccct ggatcgcagc cctggcaggg 950

 accctgccta tcttgctgct gcttctcgcc ggagccagtt acttcttgtg 1000

 gagacaacag aaggaaataa ctgctctgtc cagtgagata gaaagtgagc 1050

 aagagatgaa agaaatggga tatgctgcaa cagagcggga aataagccta 1100

 agagagagcc tccaggagga actcaagagg aaaaaatcca gtacttgact 1150

 cgtggagagg agtcttcgtc cgataccaat aagtcagcct gatgctctaa 1200

 tggaaaaatg gccctcttca agcctggtga ggaaatgctt cagatgaggc 1250

 tccaccttgt taaataaatt ggatgtatgg aaaaatagac tgcagaaaag 1300

 gggaactcat ttagctcacg agtggtcgag tgaagattga aaattaacct 1350

 ctgagggcca gcacagcagc tcatgcctgt aatcctagca ctttggaagg 1400

 ctgaggaggg cggatcacaa ggtcaggaga tcaagaccat cctggctaac 1450

 acggtgaaac cccgtctcta ctaaaaatac aaaaaataaa aaattagccg 1500

 ggcatggtga cgggcacctg tagtcccagc tactcgggag gctgaggcag 1550

 gagaatggca tgaacccgga aggcagagct tgcagtgagc cgagatcacg 1600

 ccactgcact ccagcctggg agacagagcg agactctgtc tcaagaaaaa 1650

 aaaaaaaaaa aaaaaa 1666

<210> 5752
<211> 319
<212> PRT
<213> Homo sapien

<400> 5752
 Met Lys Met Ala Ser Ser Leu Ala Phe Leu Leu Leu Asn Phe His
   1               5                  10                  15

 Val Ser Leu Leu Leu Val Gln Leu Leu Thr Pro Cys Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Lys Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asn Leu
                 140                 145                 150

 His Val Glu Val Lys Gly Tyr Glu Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Gln Trp Ser
                 170                 175                 180

 Asn Ala Lys Gly Glu Asn Ile Pro Ala Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Glu Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Gly Ser Gly Glu Gly Val Ser Cys Ile Ile Arg Asn Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Pro Trp Ile Ala Ala Leu Ala Gly Thr
                 245                 250                 255

 Leu Pro Ile Leu Leu Leu Leu Leu Ala Gly Ala Ser Tyr Phe Leu
                 260                 265                 270

 Trp Arg Gln Gln Lys Glu Ile Thr Ala Leu Ser Ser Glu Ile Glu
                 275                 280                 285

 Ser Glu Gln Glu Met Lys Glu Met Gly Tyr Ala Ala Thr Glu Arg
                 290                 295                 300

 Glu Ile Ser Leu Arg Glu Ser Leu Gln Glu Glu Leu Lys Arg Lys
                 305                 310                 315

 Lys Ser Ser Thr


<210> 5753
<211> 1658
<212> DNA
<213> Homo sapien

<400> 5753
 ggcacgagct cggctcctgg aaagatggag gcagcggaga cagaggcgga 50

 agctgcagcc ctagaggtcc tggctgaggt ggcaggcatc ttggaacctg 100

 taggcctgca ggaggaggca gaactgccag ccaagatcct ggttgagttt 150

 gtggtggact ctcagaagaa agacaagctg ctctgcagcc agcttcaggt 200

 agcggatttc ctgcagaaca tcctggctca ggaggacact gctaagggtc 250

 tcgacccctt ggcttctgaa gacacgagcc gacagaaggc aattgcagct 300

 aaggaacaat ggaaagagct gaaggccacc tacagggagc acgtagaggc 350

 catcaaaatt ggcctcacca aggccctgac tcagatggag gaagcccaga 400

 ggaaacggac acaactccgg gaagcctttg agcagctcca ggccaagaaa 450

 caaatggcca tggagaaacg cagagcagtc cagaaccagt ggcagctaca 500

 acaggagaag catctgcagc atctggcgga ggtttctgca gaggtgaggg 550

 agcgtaagac agggactcag caggagcttg acagggtgtt tcagaaactt 600

 ggaaacctga agcagcaggc agaacaggag cgggacaagc tgcagaggta 650

 tcagaccttc ctccagcttc tgtataccct gcagggtaag ctgttgttcc 700

 ctgaggctga ggctgaggca gagaatcttc cagatgataa accccagcag 750

 ccgactcgac cccaggagca gagtacagga gacaccatgg ggagagaccc 800

 tggtgtgtcc ttcaaggctg ttggtctaca acctgctgga gatgtaaatt 850

 tgccatgact tcctggagga cagcagcatg gagaaagatc ctagaaaagg 900

 cctctgactt ccctcacctc ccaaccatca ttacaggaaa gactgtgaac 950

 tcctgagttc agcttgattt ctgactacat cccagcaagc tctggcatct 1000

 gtggattaaa atccctggat ctctctcagt tgtgtatttg ttcatcttca 1050

 tatgctggca ggaacaacta ttaatacaga tactcagaag ccaataacat 1100

 gacaggagct gggactggtt tgaacacagg gtgtgcagat ggggaggggg 1150

 tactggcctt gggcctccta tgatgcagac atggtgaatt taattcaagg 1200

 aggaggagaa tgttttaggc aggtggttat atgtgggaag ataattttat 1250

 tcatggatcc aaatgtttgt tgagtccttt ctttgtgcta aggttcttgc 1300

 ggtgaaccag aattataaca gtgagctcat ctgactgttt taggatgtac 1350

 agcctagtgt taacattctt ggtatctttt tgtgccttat ctaaaacatt 1400

 tctcgatcac tggtttcaga tgttcattta ttatattctt ttcaaagatt 1450

 cagagattgg cttttgtcat ccactattgt atgttttgtt tcattgacct 1500

 ctagtgatac cttgatcttt cccactttct gttttcggat tggagaagat 1550

 gtaccttttt tgtcaactct tacttttatc agatgatcaa ctcacgtatt 1600

 tggatcttta tttgttttct caaataaata tttaaggtta aaaaaaaaaa 1650

 aaaaaaaa 1658

<210> 5754
<211> 277
<212> PRT
<213> Homo sapien

<400> 5754
 Met Glu Ala Ala Glu Thr Glu Ala Glu Ala Ala Ala Leu Glu Val
   1               5                  10                  15

 Leu Ala Glu Val Ala Gly Ile Leu Glu Pro Val Gly Leu Gln Glu
                  20                  25                  30

 Glu Ala Glu Leu Pro Ala Lys Ile Leu Val Glu Phe Val Val Asp
                  35                  40                  45

 Ser Gln Lys Lys Asp Lys Leu Leu Cys Ser Gln Leu Gln Val Ala
                  50                  55                  60

 Asp Phe Leu Gln Asn Ile Leu Ala Gln Glu Asp Thr Ala Lys Gly
                  65                  70                  75

 Leu Asp Pro Leu Ala Ser Glu Asp Thr Ser Arg Gln Lys Ala Ile
                  80                  85                  90

 Ala Ala Lys Glu Gln Trp Lys Glu Leu Lys Ala Thr Tyr Arg Glu
                  95                 100                 105

 His Val Glu Ala Ile Lys Ile Gly Leu Thr Lys Ala Leu Thr Gln
                 110                 115                 120

 Met Glu Glu Ala Gln Arg Lys Arg Thr Gln Leu Arg Glu Ala Phe
                 125                 130                 135

 Glu Gln Leu Gln Ala Lys Lys Gln Met Ala Met Glu Lys Arg Arg
                 140                 145                 150

 Ala Val Gln Asn Gln Trp Gln Leu Gln Gln Glu Lys His Leu Gln
                 155                 160                 165

 His Leu Ala Glu Val Ser Ala Glu Val Arg Glu Arg Lys Thr Gly
                 170                 175                 180

 Thr Gln Gln Glu Leu Asp Arg Val Phe Gln Lys Leu Gly Asn Leu
                 185                 190                 195

 Lys Gln Gln Ala Glu Gln Glu Arg Asp Lys Leu Gln Arg Tyr Gln
                 200                 205                 210

 Thr Phe Leu Gln Leu Leu Tyr Thr Leu Gln Gly Lys Leu Leu Phe
                 215                 220                 225

 Pro Glu Ala Glu Ala Glu Ala Glu Asn Leu Pro Asp Asp Lys Pro
                 230                 235                 240

 Gln Gln Pro Thr Arg Pro Gln Glu Gln Ser Thr Gly Asp Thr Met
                 245                 250                 255

 Gly Arg Asp Pro Gly Val Ser Phe Lys Ala Val Gly Leu Gln Pro
                 260                 265                 270

 Ala Gly Asp Val Asn Leu Pro
                 275

<210> 5755
<211> 1750
<212> DNA
<213> Homo sapien

<400> 5755
 gctttctttc cgtcgcagag agcatcggcc ggcgaccgtt ccggcggcca 50

 ttgcgaaaac ttccccacgg ctactgcgtc cacgtggcgg tggcgtgggg 100

 actccctgaa agcagagcgg cagggcgccc ggaagtcgtg agtcgagtct 150

 tcccgggcta atccatgccg ggttggaggc tgctgacgca ggtcggcgcc 200

 caggtgctgg gtcgactcgg ggacggcctg ggtgctgccc tgggcccggg 250

 gaacagaaca cacatctggc tttttgttag aggtcttcat ggaaagagtg 300

 gtacatggtg ggatgagcat ctttctgaag aaaatgtccc attcattaag 350

 cagttggtct ctgatgaaga taaagcccaa ttagcaagta aactgtgtcc 400

 tctgaaagat gaaccatggc ctatacatcc ttgggaacca ggttccttta 450

 gagttggtct tattgccttg aagctgggca tgatgccttt atggaccaag 500

 gatggtcaaa agcatgtggt cacattactt caggtacaag actgtcatgt 550

 cttaaaatat acgtcaaagg aaaactgtaa tggaaaaatg gcaaccctgt 600

 ctgtaggagg aaaaactgta tcacgttttc gtaaagctac atccatattg 650

 gaattttacc gggaacttgg attgccgccg aaacagacag ttaaaatctt 700

 taatataaca gataatgctg caattaaacc aggcactcct ctttatgctg 750

 ctcactttcg tccaggacag tatgtggatg tcacagccaa aactattggt 800

 aaaggttttc aaggtgtcat gaaaagatgg ggatttaaag gccagcctgc 850

 tacgcatggt caaacgaaaa cccacaggag acctggagct gttgcaactg 900

 gtgatattgg cagagtctgg cctggaacta aaatgcctgg aaaaatggga 950

 aacatataca ggacagaata tggactgaaa gtgtggagaa taaacacaaa 1000

 gcacaacata atctatgtaa atggctctgt acctggacat aaaaattgct 1050

 tagtaaaggt caaagattct aaactgcctg catataagga tctcggtaaa 1100

 aatctaccat tccctacata ttttcctgat ggagatgaag aggaactgcc 1150

 agaagatttg tatgatgaaa acgtgtgtca gcccggtgcg ccttctatta 1200

 catttgccta acatctttgg acgtggcaga accttacata ttctgtgagc 1250

 ttcgatgagc cagagtgata tcataaccac cagaaatcat actctccttt 1300

 cttagtcaca acaaaatcac acatgtcatc tttgtcaagg gcataaatat 1350

 atcattcata cccccattaa attttgttag aaaaattacc acattaaata 1400

 tatgagttaa gtagattgga tttgctgaaa ttggtgttgg gcatattagc 1450

 aaaatattct taatttgtgg actcgattct tttttactac atatttccca 1500

 agttatctta agatgtctgt aaatttaact tttattaaag ttttgtcaat 1550

 ctttgtgaaa tagtggttgt ggaacagtag aaaaccatat ggggactata 1600

 gtgcaaccta tttgggtaaa gaaaccattt gctaaaatgg agaaagtaaa 1650

 tagattttta tttaaattac agaaacatgt taaaggccgg acaaaggaaa 1700

 gacaataaaa tcataaatta tcggtcctgt ttaaaaaaaa aaaaaaaaaa 1750

<210> 5756
<211> 348
<212> PRT
<213> Homo sapien

<400> 5756
 Met Pro Gly Trp Arg Leu Leu Thr Gln Val Gly Ala Gln Val Leu
   1               5                  10                  15

 Gly Arg Leu Gly Asp Gly Leu Gly Ala Ala Leu Gly Pro Gly Asn
                  20                  25                  30

 Arg Thr His Ile Trp Leu Phe Val Arg Gly Leu His Gly Lys Ser
                  35                  40                  45

 Gly Thr Trp Trp Asp Glu His Leu Ser Glu Glu Asn Val Pro Phe
                  50                  55                  60

 Ile Lys Gln Leu Val Ser Asp Glu Asp Lys Ala Gln Leu Ala Ser
                  65                  70                  75

 Lys Leu Cys Pro Leu Lys Asp Glu Pro Trp Pro Ile His Pro Trp
                  80                  85                  90

 Glu Pro Gly Ser Phe Arg Val Gly Leu Ile Ala Leu Lys Leu Gly
                  95                 100                 105

 Met Met Pro Leu Trp Thr Lys Asp Gly Gln Lys His Val Val Thr
                 110                 115                 120

 Leu Leu Gln Val Gln Asp Cys His Val Leu Lys Tyr Thr Ser Lys
                 125                 130                 135

 Glu Asn Cys Asn Gly Lys Met Ala Thr Leu Ser Val Gly Gly Lys
                 140                 145                 150

 Thr Val Ser Arg Phe Arg Lys Ala Thr Ser Ile Leu Glu Phe Tyr
                 155                 160                 165

 Arg Glu Leu Gly Leu Pro Pro Lys Gln Thr Val Lys Ile Phe Asn
                 170                 175                 180

 Ile Thr Asp Asn Ala Ala Ile Lys Pro Gly Thr Pro Leu Tyr Ala
                 185                 190                 195

 Ala His Phe Arg Pro Gly Gln Tyr Val Asp Val Thr Ala Lys Thr
                 200                 205                 210

 Ile Gly Lys Gly Phe Gln Gly Val Met Lys Arg Trp Gly Phe Lys
                 215                 220                 225

 Gly Gln Pro Ala Thr His Gly Gln Thr Lys Thr His Arg Arg Pro
                 230                 235                 240

 Gly Ala Val Ala Thr Gly Asp Ile Gly Arg Val Trp Pro Gly Thr
                 245                 250                 255

 Lys Met Pro Gly Lys Met Gly Asn Ile Tyr Arg Thr Glu Tyr Gly
                 260                 265                 270

 Leu Lys Val Trp Arg Ile Asn Thr Lys His Asn Ile Ile Tyr Val
                 275                 280                 285

 Asn Gly Ser Val Pro Gly His Lys Asn Cys Leu Val Lys Val Lys
                 290                 295                 300

 Asp Ser Lys Leu Pro Ala Tyr Lys Asp Leu Gly Lys Asn Leu Pro
                 305                 310                 315

 Phe Pro Thr Tyr Phe Pro Asp Gly Asp Glu Glu Glu Leu Pro Glu
                 320                 325                 330

 Asp Leu Tyr Asp Glu Asn Val Cys Gln Pro Gly Ala Pro Ser Ile
                 335                 340                 345

 Thr Phe Ala


<210> 5757
<211> 1770
<212> DNA
<213> Homo sapien

<400> 5757
 gaggagtgga ttacatattc caacagttgt tattacattg gtaaggaaag 50

 aagaacttgg gaagaaagag tttgctggcc tgtgcttcga agaactctga 100

 tctgctttct atagataatg aggaagaaat ggtatgtgtg gggacttccc 150

 agttggctgt aagttgccat ttgaactaaa cgaaatagat caggaactga 200

 ggacatatct aaattttcta gttttataga aggcttttat ccacaagaat 250

 caagatcttc cctctctgag caggaatcct ttgtgcattg aagactttag 300

 attcctctct gcggtagacg tgcacttata agtatttgat ggggtggatt 350

 cgtggtcgga ggtctcgaca cagctgggag atgagtgaat ttcataatta 400

 taacttggat ctgaagaaga gtgatttttc aacacgatgg caaaagcaaa 450

 gatgtccagt agtcaaaagc aaatgtagag aaaatgcatc tccatttttt 500

 ttctgctgct tcatcgctgt agccatggga atccgtttca ttattatggt 550

 agcaatatgg agtgctgtat tcctaaactc attattcaac caagaagttc 600

 aaattccctt gaccgaaagt tactgtggcc catgtcctaa aaactggata 650

 tgttacaaaa ataactgcta ccaatttttt gatgagagta aaaactggta 700

 tgagagccag gcttcttgta tgtctcaaaa tgccagcctt ctgaaagtat 750

 acagcaaaga ggaccaggat ttacttaaac tggtgaagtc atatcattgg 800

 atgggactag tacacattcc aacaaatgga tcttggcagt gggaagatgg 850

 ctccattctc tcacccaacc tactaacaat aattgaaatg cagaagggag 900

 actgtgcact ctatgcctcg agctttaaag gctatataga aaactgttca 950

 actccaaata catacatctg catgcaaagg actgtgtaaa gatgatcaac 1000

 catctcaata aaagccagga acagagaaga gattacacca gcggtaacac 1050

 tgccaaccga gactaaagga aacaaacaaa aacaggacaa aatgaccaaa 1100

 gactgtcaga tttcttagac tccacaggac caaaccatag aacaatttca 1150

 ctgcaaacat gcatgattct ccaagacaaa agaagagaga tcctaaaggc 1200

 aattcagata tccccaaggc tgcctctccc accacaagcc cagagtggat 1250

 gggctggggg aggggtgctg ttttaatttc taaaggtagg accaacaccc 1300

 aggggatcag tgaaggaaga gaaggccagc agatcagtga gagtgcaacc 1350

 ccaccctcca caggaaattg cctcatgggc agggccacag cagagagaca 1400

 cagcatgggc agtgccttcc ctgcctgtgg gggtcatgct gccactttta 1450

 atgggtcctc cacccaacgg ggtcagggag gtggtgctgc cccagtgggc 1500

 catgattatc ttaaaggcat tattctccag ccttaagatc ttaggacgtt 1550

 tcctttgcta tgatttgtac ttgcttgagt cccatgactg tttctcttcc 1600

 tctctttctt ccttttggaa tagtaatatc catcctatgt ttgtcccact 1650

 attgtatttt ggaagcacat aacttgtttg gtttcacagg ttcacagtta 1700

 agaaggaatt ttgcctctga ataaatagaa tcttgagtct catgcaaaaa 1750

 aaaaaaaaaa aaaaaaaaaa 1770

<210> 5758
<211> 216
<212> PRT
<213> Homo sapien

<400> 5758
 Met Gly Trp Ile Arg Gly Arg Arg Ser Arg His Ser Trp Glu Met
   1               5                  10                  15

 Ser Glu Phe His Asn Tyr Asn Leu Asp Leu Lys Lys Ser Asp Phe
                  20                  25                  30

 Ser Thr Arg Trp Gln Lys Gln Arg Cys Pro Val Val Lys Ser Lys
                  35                  40                  45

 Cys Arg Glu Asn Ala Ser Pro Phe Phe Phe Cys Cys Phe Ile Ala
                  50                  55                  60

 Val Ala Met Gly Ile Arg Phe Ile Ile Met Val Ala Ile Trp Ser
                  65                  70                  75

 Ala Val Phe Leu Asn Ser Leu Phe Asn Gln Glu Val Gln Ile Pro
                  80                  85                  90

 Leu Thr Glu Ser Tyr Cys Gly Pro Cys Pro Lys Asn Trp Ile Cys
                  95                 100                 105

 Tyr Lys Asn Asn Cys Tyr Gln Phe Phe Asp Glu Ser Lys Asn Trp
                 110                 115                 120

 Tyr Glu Ser Gln Ala Ser Cys Met Ser Gln Asn Ala Ser Leu Leu
                 125                 130                 135

 Lys Val Tyr Ser Lys Glu Asp Gln Asp Leu Leu Lys Leu Val Lys
                 140                 145                 150

 Ser Tyr His Trp Met Gly Leu Val His Ile Pro Thr Asn Gly Ser
                 155                 160                 165

 Trp Gln Trp Glu Asp Gly Ser Ile Leu Ser Pro Asn Leu Leu Thr
                 170                 175                 180

 Ile Ile Glu Met Gln Lys Gly Asp Cys Ala Leu Tyr Ala Ser Ser
                 185                 190                 195

 Phe Lys Gly Tyr Ile Glu Asn Cys Ser Thr Pro Asn Thr Tyr Ile
                 200                 205                 210

 Cys Met Gln Arg Thr Val
                 215

<210> 5759
<211> 3772
<212> DNA
<213> Homo sapien

<400> 5759
 agcgggataa gttggcgcgt cacctagacg tcagcctctt acctctcgga 50

 cgtcccgtcc caggagcaaa actctagtga ctttgggccc gcccccgtga 100

 gagtggaggg cggccgatga gggcggttct gaagggaaca agaccaatga 150

 gacgagcccg gggcggggcg cggggccgga gggtggggcg ggtggcggcg 200

 gtggcagtcc gaggtctggc tccgcgcagt atatgacagt acgtcagcag 250

 cgggatggcc ctagcagtgg cggcggctgc agaagcccaa gcagccgcgg 300

 ccgcagtgga ggctagagcc ggagcggcgg cggcggcggc accccgggga 350

 gtttaagatg gcggcggggg ggacaggggg cctgcgggag gagcagcgct 400

 atgggctgtc gtgcggacgg ctggggcagg acaacatcac cgtactgcat 450

 gtgaagctca ccgagacggc gatccgggcg ctcgagactt accagagcca 500

 caagaattta attccttttc gaccttcaat ccagttccaa ggactccacg 550

 ggcttgtcaa aattcccaaa aatgatcccc tcaatgaagt tcataacttt 600

 aacttttatt tgtcaaatgt gggcaaagac aaccctcagg gcagctttga 650

 ctgcatccag caaacattct ccagctctgg agcctcccag ctcaattgcc 700

 tgggatttat acaagataaa attacagtgt gtgcaacaaa cgactcgtat 750

 cagatgacac gagaaagaat gacccaggca gaggaggaat cccgcaaccg 800

 aagcacaaaa gttatcaaac ccggtggacc atatgtaggg aaaagagtgc 850

 aaattcggaa agcacctcaa gctgtttcag atacagttcc tgagaggaaa 900

 aggtcaaccc ccatgaaccc tgcaaataca attcgaaaga cacatagcag 950

 cagcaccatc tctcagaggc catacaggga cagggtgatt cacttactgg 1000

 ccctgaaggc ctacaagaaa ccggagctac ttgctagact ccagaaagat 1050

 ggtgtcaatc aaaaagacaa gaactccctg ggagcaattc tgcaacaggt 1100

 agccaatctg aattctaagg acctctcata taccttaaag gattatgttt 1150

 ttaaagagct tcaaagagac tggcctggat acagtgaaat agacagacgg 1200

 tcattggagt cagtgctctc tagaaaacta aatccgtctc agaatgctac 1250

 aggcaccagc cgttcagaat ctcctgtatg ttctagtaga gatgctgtat 1300

 cttctcctca gaaacggctt ttggattcag agtttattga tcctttaatg 1350

 aataaaaaag cccgaatatc tcacctgacg aacagagtac caccaacact 1400

 aaatggtcat ttgaatccca ccagtgaaaa atcggctgca ggcctcccac 1450

 tgccccctgc ggctgctgcc atccccaccc ctccaccgct gccttcaacc 1500

 tatctgccca tctcacatcc tcctcagatt gtaaattcta actccaactc 1550

 ccctagcact ccagaaggcc gggggactca agacctacct gttgacagtt 1600

 ttagtcaaaa cgatagtatc tatgaggacc agcaagacaa atatacctct 1650

 aggacttctc tggaaacctt accccctggt tccgttctac taaagtgtcc 1700

 aaagcctatg gaagaaaacc attcaatgtc tcacaaaaag tccaaaaaga 1750

 agtctaaaaa acataaggaa aaggaccaaa taaaaaagca cgacattgag 1800

 actattgagg aaaaggagga agatcttaag agagaagagg aaattgccaa 1850

 gctaaataac tccagtccaa attccagtgg aggagttaaa gaggattgca 1900

 ctgcctccat ggaaccttca gcaattgaac tcccagatta tttgataaaa 1950

 tatatcgcta tcgtctccta tgagcaacgc cagaattata aggatgactt 2000

 caatgcagag tatgatgagt acagagcttt gcatgccagg atggagactg 2050

 tagctagaag atttatcaaa ctagatgcac aaagaaagcg cctttctcca 2100

 ggctcaaaag agtatcagaa tgttcatgaa gaagtcttac aagaatatca 2150

 gaagataaag cagtctagtc ccaattacca tgaagaaaaa tacagatgtg 2200

 aatatcttca taacaagctg gctcacatca aaaggctaat aggtgaattt 2250

 gaccaacagc aagcagagtc atggtcctag aactctgctt ggaccagaag 2300

 atgtgaataa acttaagctt atttatttaa aattccaaat gagttgctct 2350

 agattctaaa aaggtgaaac tttggctgtt gaaagtttca gtattagtaa 2400

 acttgagtta ctttttcttt tccattttac tttgcttccc tgcatttcga 2450

 agctgctctt tctggtcctc cccaccaccc cacccccaag acttgtgttt 2500

 gttaatagaa ataatttttt taggtattgg ggatccattg tctatatttc 2550

 aaatcagttt tttttcctca aaaacttgtg tttgttatta gaaatgattt 2600

 tttagatatt ggggatccag tgtccacact taaaagttgt atgtgtttaa 2650

 aaaacaacaa cagtaatgtg caaggtgaaa tgcttttgga taaacgtaag 2700

 cctattttct gacgtttctt aatgcaaact ctttgcctta aatggtagaa 2750

 tatttagaaa tttgcacaaa attaaaaaaa taaacattgt cttggagggt 2800

 taaaaaatag aaaggtgtat gtgtatagat tcacatacac atatgtatat 2850

 acaggctgac ttgatctaga acattaaatc cgccctgcaa gttaaccccc 2900

 cattgcaatg gttgccttaa ggtgtttgct agttgtgtac atagtgtggt 2950

 taatcattag ctacactgct tcccacttga ttagagcaat gggaagcata 3000

 ctgtggccta ccagcatctg gaagtgtgtg ctcgatctgt atgtgtgcag 3050

 aggtggtgtg gatgtgagcg tgcatgaagg aaaaaaagct gctactccta 3100

 gtaggccaaa cgctcaggtt aaacaactga cgagtgttac tgtagggtgt 3150

 ttttttgttt ttttgttttt tttcttctat caaattgcta cttttgttgt 3200

 ggaagacaaa agcatttcca tttcaacgag tttgtcagct ttattaatgt 3250

 tgggcaaaaa ttgatatgtc atgaaaatga aacagatcta tagttttggg 3300

 acaaaattat aaaatgaaat gtgtaggtaa cctatttata tactgctata 3350

 aagtattttt tgaagagaga tatgcaaaga agctattacc tacataagag 3400

 gtatatttaa agattttttt tttttcatcc tggtgccagg aatataaaaa 3450

 agagtggata tatttaacca taacatactg tgattcatca aacagcacaa 3500

 actttcattt catggagttt atctgttgac attgatttaa actgtcactt 3550

 gttttatcat gtgggaacat aagttatgtg gtcaaaaata taaggatttt 3600

 gaattaatgt tgattcaagt tgtattgtct tattgtattg tcttttcaaa 3650

 gtgctgccag ttgaaaaggg aagcattatg tttacaaatc tgttttgaaa 3700

 tgtttgccaa aattttggta gtgtctttaa taaagatgtt tgtctccagc 3750

 atccagaaaa aaaaaaaaaa aa 3772

<210> 5760
<211> 640
<212> PRT
<213> Homo sapien

<400> 5760
 Met Ala Ala Gly Gly Thr Gly Gly Leu Arg Glu Glu Gln Arg Tyr
   1               5                  10                  15

 Gly Leu Ser Cys Gly Arg Leu Gly Gln Asp Asn Ile Thr Val Leu
                  20                  25                  30

 His Val Lys Leu Thr Glu Thr Ala Ile Arg Ala Leu Glu Thr Tyr
                  35                  40                  45

 Gln Ser His Lys Asn Leu Ile Pro Phe Arg Pro Ser Ile Gln Phe
                  50                  55                  60

 Gln Gly Leu His Gly Leu Val Lys Ile Pro Lys Asn Asp Pro Leu
                  65                  70                  75

 Asn Glu Val His Asn Phe Asn Phe Tyr Leu Ser Asn Val Gly Lys
                  80                  85                  90

 Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile Gln Gln Thr Phe Ser
                  95                 100                 105

 Ser Ser Gly Ala Ser Gln Leu Asn Cys Leu Gly Phe Ile Gln Asp
                 110                 115                 120

 Lys Ile Thr Val Cys Ala Thr Asn Asp Ser Tyr Gln Met Thr Arg
                 125                 130                 135

 Glu Arg Met Thr Gln Ala Glu Glu Glu Ser Arg Asn Arg Ser Thr
                 140                 145                 150

 Lys Val Ile Lys Pro Gly Gly Pro Tyr Val Gly Lys Arg Val Gln
                 155                 160                 165

 Ile Arg Lys Ala Pro Gln Ala Val Ser Asp Thr Val Pro Glu Arg
                 170                 175                 180

 Lys Arg Ser Thr Pro Met Asn Pro Ala Asn Thr Ile Arg Lys Thr
                 185                 190                 195

 His Ser Ser Ser Thr Ile Ser Gln Arg Pro Tyr Arg Asp Arg Val
                 200                 205                 210

 Ile His Leu Leu Ala Leu Lys Ala Tyr Lys Lys Pro Glu Leu Leu
                 215                 220                 225

 Ala Arg Leu Gln Lys Asp Gly Val Asn Gln Lys Asp Lys Asn Ser
                 230                 235                 240

 Leu Gly Ala Ile Leu Gln Gln Val Ala Asn Leu Asn Ser Lys Asp
                 245                 250                 255

 Leu Ser Tyr Thr Leu Lys Asp Tyr Val Phe Lys Glu Leu Gln Arg
                 260                 265                 270

 Asp Trp Pro Gly Tyr Ser Glu Ile Asp Arg Arg Ser Leu Glu Ser
                 275                 280                 285

 Val Leu Ser Arg Lys Leu Asn Pro Ser Gln Asn Ala Thr Gly Thr
                 290                 295                 300

 Ser Arg Ser Glu Ser Pro Val Cys Ser Ser Arg Asp Ala Val Ser
                 305                 310                 315

 Ser Pro Gln Lys Arg Leu Leu Asp Ser Glu Phe Ile Asp Pro Leu
                 320                 325                 330

 Met Asn Lys Lys Ala Arg Ile Ser His Leu Thr Asn Arg Val Pro
                 335                 340                 345

 Pro Thr Leu Asn Gly His Leu Asn Pro Thr Ser Glu Lys Ser Ala
                 350                 355                 360

 Ala Gly Leu Pro Leu Pro Pro Ala Ala Ala Ala Ile Pro Thr Pro
                 365                 370                 375

 Pro Pro Leu Pro Ser Thr Tyr Leu Pro Ile Ser His Pro Pro Gln
                 380                 385                 390

 Ile Val Asn Ser Asn Ser Asn Ser Pro Ser Thr Pro Glu Gly Arg
                 395                 400                 405

 Gly Thr Gln Asp Leu Pro Val Asp Ser Phe Ser Gln Asn Asp Ser
                 410                 415                 420

 Ile Tyr Glu Asp Gln Gln Asp Lys Tyr Thr Ser Arg Thr Ser Leu
                 425                 430                 435

 Glu Thr Leu Pro Pro Gly Ser Val Leu Leu Lys Cys Pro Lys Pro
                 440                 445                 450

 Met Glu Glu Asn His Ser Met Ser His Lys Lys Ser Lys Lys Lys
                 455                 460                 465

 Ser Lys Lys His Lys Glu Lys Asp Gln Ile Lys Lys His Asp Ile
                 470                 475                 480

 Glu Thr Ile Glu Glu Lys Glu Glu Asp Leu Lys Arg Glu Glu Glu
                 485                 490                 495

 Ile Ala Lys Leu Asn Asn Ser Ser Pro Asn Ser Ser Gly Gly Val
                 500                 505                 510

 Lys Glu Asp Cys Thr Ala Ser Met Glu Pro Ser Ala Ile Glu Leu
                 515                 520                 525

 Pro Asp Tyr Leu Ile Lys Tyr Ile Ala Ile Val Ser Tyr Glu Gln
                 530                 535                 540

 Arg Gln Asn Tyr Lys Asp Asp Phe Asn Ala Glu Tyr Asp Glu Tyr
                 545                 550                 555

 Arg Ala Leu His Ala Arg Met Glu Thr Val Ala Arg Arg Phe Ile
                 560                 565                 570

 Lys Leu Asp Ala Gln Arg Lys Arg Leu Ser Pro Gly Ser Lys Glu
                 575                 580                 585

 Tyr Gln Asn Val His Glu Glu Val Leu Gln Glu Tyr Gln Lys Ile
                 590                 595                 600

 Lys Gln Ser Ser Pro Asn Tyr His Glu Glu Lys Tyr Arg Cys Glu
                 605                 610                 615

 Tyr Leu His Asn Lys Leu Ala His Ile Lys Arg Leu Ile Gly Glu
                 620                 625                 630

 Phe Asp Gln Gln Gln Ala Glu Ser Trp Ser
                 635                 640

<210> 5761
<211> 3415
<212> DNA
<213> Homo sapien

<400> 5761
 gggagcagct agggcgcggg tctccctcct cccggagttt ggaacggctg 50

 aagttcacct tccagcccct agcgccgttc gcgccgctag gcctggcttc 100

 tgaggcggtt gcggtgctcg gtcgccgcct aggcggggca gggtgcgagc 150

 aggggcttcg ggccacgctt ctcttggcga caggattttg ctgaagtccg 200

 tccgggaaac ggaggaaaaa aagagttgcg ggaggctgtc ggctaataac 250

 ggttcttgat acatatttgc cagacttcaa gatttcagaa aaggggtgaa 300

 agagaagatt gcaactttga gtcagacctg taggcctgat agactgatta 350

 aaccacagaa ggtgacctgc tgagaaaagt ggtacaaata ctgggaaaaa 400

 cctgctcttc tgcgttaagt gggagacaat gtcacaagtt aaaagctctt 450

 attcctatga tgccccctcg gatttcatca atttttcatc cttggatgat 500

 gaaggagata ctcaaaacat agattcatgg tttgaggaga aggccaattt 550

 ggagaataag ttactgggga agaatggaac tggagggctt tttcagggca 600

 aaactccttt gagaaaggct aatcttcagc aagctattgt cacacctttg 650

 aaaccagttg acaacactta ctacaaagag gcagaaaaag aaaatcttgt 700

 ggaacaatcc attccgtcaa atgcttgttc ttccctggaa gttgaggcag 750

 ccatatcaag aaaaactcca gcccagcctc agagaagatc tcttaggctt 800

 tctgctcaga aggatttgga acagaaagaa aagcatcatg taaaaatgaa 850

 agccaagaga tgtgccactc ctgtaatcat cgatgaaatt ctaccctcta 900

 agaaaatgaa agtttctaac aacaaaaaga agccagagga agaaggcagt 950

 gctcatcaag atactgctga aaagaatgca tcttccccag agaaagccaa 1000

 gggtagacat actgtgcctt gtatgccacc tgcaaagcag aagtttctaa 1050

 aaagtactga ggagcaagag ctggagaaga gtatgaaaat gcagcaagag 1100

 gtggtggaga tgcggaaaaa gaatgaagaa ttcaagaaac ttgctctggc 1150

 tggaataggg caacctgtga agaaatcagt gagccaggtc accaaatcag 1200

 ttgacttcca cttccgcaca gatgagcgaa tcaaacaaca tcctaagaac 1250

 caggaggaat ataaggaagt gaactttaca tctgaactac gaaagcatcc 1300

 ttcatctcct gcccgagtga ctaagggatg taccattgtt aagcctttca 1350

 acctgtccca aggaaagaaa agaacatttg atgaaacagt ttctacatat 1400

 gtgccccttg cacagcaagt tgaagacttc cataaacgaa cccctaacag 1450

 atatcatttg aggagcaaga aggatgatat taacctgtta ccctccaaat 1500

 cttctgtgac caagatttgc agagacccac agactcctgt actgcaaacc 1550

 aaacaccgtg cacgggctgt gacctgcaaa agtacagcag agctggaggc 1600

 tgaggagctc gagaaattgc aacaatacaa attcaaagca cgtgaacttg 1650

 atcccagaat acttgaaggt gggcccatct tgcccaagaa accacctgtg 1700

 aaaccaccca ccgagcctat tggctttgat ttggaaattg agaaaagaat 1750

 ccaggagcga gaatcaaaga agaaaacaga ggatgaacac tttgaatttc 1800

 attccagacc ttgccctact aagattttgg aagatgttgt gggtgttcct 1850

 gaaaagaagg tacttccaat caccgtcccc aagtcaccag cctttgcatt 1900

 gaagaacaga attcgaatgc ccaccaaaga agatgaggaa gaggacgaac 1950

 cggtagtgat aaaagctcaa cctgtgccac attatggggt gccttttaag 2000

 ccccaaatcc cagaggcaag aactgtggaa atatgccctt tctcgtttga 2050

 ttctcgagac aaagaacgtc agttacagaa ggagaagaaa ataaaagaac 2100

 tgcagaaagg ggaggtgccc aagttcaagg cacttccctt gcctcatttt 2150

 gacaccatta acctgccaga gaagaaggta aagaatgtga cccagattga 2200

 acctttctgc ttggagactg acagaagagg tgctctgaag gcacagactt 2250

 ggaagcacca gctggaagaa gaactgagac agcagaaaga agcagcttgt 2300

 ttcaaggctc gtccaaacac cgtcatctct caggagccct ttgttcccaa 2350

 gaaagagaag aaatcagttg ctgagggcct ttctggttct ctagttcagg 2400

 aaccttttca gctggctact gagaagagag ccaaagagcg gcaggagctg 2450

 gagaagagaa tggctgaggt agaagcccag aaagcccagc agttggagga 2500

 ggccagacta caggaggaag agcagaaaaa agaggagctg gccaggctac 2550

 ggagagaact ggtgcataag gcaaatccaa tacgcaagta ccagggtctg 2600

 gagataaagt caagtgacca gcctctgact gtgcctgtat ctcccaaatt 2650

 ctccactcga ttccactgct aaactcagct gtgagctgcg gataccgccc 2700

 ggcaatggga cctgctctta acctcaaacc taggaccgtc ttgctttgtc 2750

 attgggcatg gagagaaccc atttctccag acttttacct acccgtgcct 2800

 gagaaagcat acttgacaac tgtggactcc agttttgttg agaattgttt 2850

 tcttacatta ctaaggctaa taatgagatg taactcatga atgtctcgat 2900

 tagactccat gtagttactt cctttaaacc atcagccggc cttttatatg 2950

 ggtcttcact ctgactagaa tttagtctct gtgtcagcac agtgtaatct 3000

 ctattgctat tgccccttac gactctcacc ctctccccac tttttttaaa 3050

 aattttaacc agaaaataaa gatagttaaa tcctaagata gagattaagt 3100

 catggtttaa atgaggaaca atcagtaaat cagattctgt cctcttctct 3150

 gcataccgtg aatttatagt taaggatccc tttgctgtga gggtagaaaa 3200

 cctcaccaac tgcaccagtg aggaagaaga ctgcgtggat tcatggggag 3250

 cctcacagca gccacgcagc aggctctggg tggggctgcc gttaaggcac 3300

 gttctttcct tactggtgct gataacaaca gggaaccgtg cagtgtgcat 3350

 tttaagacct ggcctggaat aaatacgttt tgtctttccc tcaaaaaaaa 3400

 aaaaaaaaaa aaaaa 3415

<210> 5762
<211> 747
<212> PRT
<213> Homo sapien

<400> 5762
 Met Ser Gln Val Lys Ser Ser Tyr Ser Tyr Asp Ala Pro Ser Asp
   1               5                  10                  15

 Phe Ile Asn Phe Ser Ser Leu Asp Asp Glu Gly Asp Thr Gln Asn
                  20                  25                  30

 Ile Asp Ser Trp Phe Glu Glu Lys Ala Asn Leu Glu Asn Lys Leu
                  35                  40                  45

 Leu Gly Lys Asn Gly Thr Gly Gly Leu Phe Gln Gly Lys Thr Pro
                  50                  55                  60

 Leu Arg Lys Ala Asn Leu Gln Gln Ala Ile Val Thr Pro Leu Lys
                  65                  70                  75

 Pro Val Asp Asn Thr Tyr Tyr Lys Glu Ala Glu Lys Glu Asn Leu
                  80                  85                  90

 Val Glu Gln Ser Ile Pro Ser Asn Ala Cys Ser Ser Leu Glu Val
                  95                 100                 105

 Glu Ala Ala Ile Ser Arg Lys Thr Pro Ala Gln Pro Gln Arg Arg
                 110                 115                 120

 Ser Leu Arg Leu Ser Ala Gln Lys Asp Leu Glu Gln Lys Glu Lys
                 125                 130                 135

 His His Val Lys Met Lys Ala Lys Arg Cys Ala Thr Pro Val Ile
                 140                 145                 150

 Ile Asp Glu Ile Leu Pro Ser Lys Lys Met Lys Val Ser Asn Asn
                 155                 160                 165

 Lys Lys Lys Pro Glu Glu Glu Gly Ser Ala His Gln Asp Thr Ala
                 170                 175                 180

 Glu Lys Asn Ala Ser Ser Pro Glu Lys Ala Lys Gly Arg His Thr
                 185                 190                 195

 Val Pro Cys Met Pro Pro Ala Lys Gln Lys Phe Leu Lys Ser Thr
                 200                 205                 210

 Glu Glu Gln Glu Leu Glu Lys Ser Met Lys Met Gln Gln Glu Val
                 215                 220                 225

 Val Glu Met Arg Lys Lys Asn Glu Glu Phe Lys Lys Leu Ala Leu
                 230                 235                 240

 Ala Gly Ile Gly Gln Pro Val Lys Lys Ser Val Ser Gln Val Thr
                 245                 250                 255

 Lys Ser Val Asp Phe His Phe Arg Thr Asp Glu Arg Ile Lys Gln
                 260                 265                 270

 His Pro Lys Asn Gln Glu Glu Tyr Lys Glu Val Asn Phe Thr Ser
                 275                 280                 285

 Glu Leu Arg Lys His Pro Ser Ser Pro Ala Arg Val Thr Lys Gly
                 290                 295                 300

 Cys Thr Ile Val Lys Pro Phe Asn Leu Ser Gln Gly Lys Lys Arg
                 305                 310                 315

 Thr Phe Asp Glu Thr Val Ser Thr Tyr Val Pro Leu Ala Gln Gln
                 320                 325                 330

 Val Glu Asp Phe His Lys Arg Thr Pro Asn Arg Tyr His Leu Arg
                 335                 340                 345

 Ser Lys Lys Asp Asp Ile Asn Leu Leu Pro Ser Lys Ser Ser Val
                 350                 355                 360

 Thr Lys Ile Cys Arg Asp Pro Gln Thr Pro Val Leu Gln Thr Lys
                 365                 370                 375

 His Arg Ala Arg Ala Val Thr Cys Lys Ser Thr Ala Glu Leu Glu
                 380                 385                 390

 Ala Glu Glu Leu Glu Lys Leu Gln Gln Tyr Lys Phe Lys Ala Arg
                 395                 400                 405

 Glu Leu Asp Pro Arg Ile Leu Glu Gly Gly Pro Ile Leu Pro Lys
                 410                 415                 420

 Lys Pro Pro Val Lys Pro Pro Thr Glu Pro Ile Gly Phe Asp Leu
                 425                 430                 435

 Glu Ile Glu Lys Arg Ile Gln Glu Arg Glu Ser Lys Lys Lys Thr
                 440                 445                 450

 Glu Asp Glu His Phe Glu Phe His Ser Arg Pro Cys Pro Thr Lys
                 455                 460                 465

 Ile Leu Glu Asp Val Val Gly Val Pro Glu Lys Lys Val Leu Pro
                 470                 475                 480

 Ile Thr Val Pro Lys Ser Pro Ala Phe Ala Leu Lys Asn Arg Ile
                 485                 490                 495

 Arg Met Pro Thr Lys Glu Asp Glu Glu Glu Asp Glu Pro Val Val
                 500                 505                 510

 Ile Lys Ala Gln Pro Val Pro His Tyr Gly Val Pro Phe Lys Pro
                 515                 520                 525

 Gln Ile Pro Glu Ala Arg Thr Val Glu Ile Cys Pro Phe Ser Phe
                 530                 535                 540

 Asp Ser Arg Asp Lys Glu Arg Gln Leu Gln Lys Glu Lys Lys Ile
                 545                 550                 555

 Lys Glu Leu Gln Lys Gly Glu Val Pro Lys Phe Lys Ala Leu Pro
                 560                 565                 570

 Leu Pro His Phe Asp Thr Ile Asn Leu Pro Glu Lys Lys Val Lys
                 575                 580                 585

 Asn Val Thr Gln Ile Glu Pro Phe Cys Leu Glu Thr Asp Arg Arg
                 590                 595                 600

 Gly Ala Leu Lys Ala Gln Thr Trp Lys His Gln Leu Glu Glu Glu
                 605                 610                 615

 Leu Arg Gln Gln Lys Glu Ala Ala Cys Phe Lys Ala Arg Pro Asn
                 620                 625                 630

 Thr Val Ile Ser Gln Glu Pro Phe Val Pro Lys Lys Glu Lys Lys
                 635                 640                 645

 Ser Val Ala Glu Gly Leu Ser Gly Ser Leu Val Gln Glu Pro Phe
                 650                 655                 660

 Gln Leu Ala Thr Glu Lys Arg Ala Lys Glu Arg Gln Glu Leu Glu
                 665                 670                 675

 Lys Arg Met Ala Glu Val Glu Ala Gln Lys Ala Gln Gln Leu Glu
                 680                 685                 690

 Glu Ala Arg Leu Gln Glu Glu Glu Gln Lys Lys Glu Glu Leu Ala
                 695                 700                 705

 Arg Leu Arg Arg Glu Leu Val His Lys Ala Asn Pro Ile Arg Lys
                 710                 715                 720

 Tyr Gln Gly Leu Glu Ile Lys Ser Ser Asp Gln Pro Leu Thr Val
                 725                 730                 735

 Pro Val Ser Pro Lys Phe Ser Thr Arg Phe His Cys
                 740                 745

<210> 5763
<211> 3690
<212> DNA
<213> Homo sapien

<400> 5763
 gggccggggt gcggagggag tccctgaaac ttctcccaac agccccaggg 50

 ccaatcttcc ctcagcccac tcccctcttc gccagctccc aggtccccac 100

 tcctgtaccg ggggtggggt ggggagccag gcccgtctcc cgctgggaca 150

 cacacagggg ccggggagcg gggacgggac ccccgaggcg ggggggacga 200

 accgacagac agacggctgg gcgcccgccc cagcgggcag gcaggcagga 250

 ggaggcggag gcgggggtac gacggggagc actgggtctg gggagtttcc 300

 tctcaactat cgggggagaa actccccgca gccggaggaa agacccagac 350

 agtgttttcc tcccgggggc cgtgctcccc cgccccgcgt agcggcggtc 400

 gccgccaccg gcgcctccac ctctaccatc tcctctttct ccaccacctc 450

 gggccccggt gtccccggcc agcactatgc ccatcttact gttcctgata 500

 gacacgtctg cctctatgaa ccagcgcagc catctgggca ccacctacct 550

 ggacacggcc aaaggcgcgg tagagacctt catgaagctc cgtgcccggg 600

 accctgccag cagaggagac aggtatatgc tggtcacttt cgaagagccg 650

 ccctatgcta tcaaggctgg atggaaagaa aaccatgcaa cgtttatgaa 700

 tgaattgaaa aaccttcagg ctgaaggact tacgactctt ggccaatccc 750

 taaggacagc ttttgattta ttaaatttaa atagattagt aactggcata 800

 gacaactatg ggcagggaag aaaccctttt ttcttggagc cagcaataat 850

 tatcacaatt actgatggga gcaagttgac taccaccagt ggagtccagg 900

 atgagcttca tttacctctt aattctcctt tgcctggaag tgaattgacc 950

 aaggaacctt ttcgttggga tcagagactc tttgcattag tgttgcggtt 1000

 gcctggcacc atgtcagtag aatcagaaca gttgacaggt gtgcctttag 1050

 atgactctgc aatcacacca atgtgtgaag tgacaggcgg ccgttcatat 1100

 tctgtgtgtt ctccaagaat gcttaatcag tgtctggagt ccttggtgca 1150

 gaaagtacaa agtggggtgg taataaactt tgaaaaagca ggaccagatc 1200

 cttcccctgt agaagatggg cagccagata tatcaaggcc ttttggatct 1250

 cagccttggc atagctgtca caaactcata tatgtcagac caaatcctaa 1300

 aactggggtt cctataggtc attggcctgt tccagagtct ttttggccag 1350

 atcaaaattc gccaacacta ccacctcgta catctcatcc tgtagtgaag 1400

 ttttcctgta cagactgtga accaatggtt attgataaac ttccttttga 1450

 caaatatgag ttggaacctt caccactgac tcaatttatc ctggaaagga 1500

 aatctcctca aacatgttgg caggtgtacg tgagcaatag tgcaaaatac 1550

 agtgaacttg gtcatccttt tggttacttg aaagccagta cagcactgaa 1600

 ctgtgtcaac ttatttgtga tgccttacaa ttatccagtc cttcttcccc 1650

 tcttagatga cttgtttaaa gtgcataaag caaaaccaac attgaagtgg 1700

 agacagtcat ttgaaagtta tttgaagaca atgcctccct actatcttgg 1750

 gcccttgaag aaagctgtta ggatgatggg agcacctaac ctaatagcag 1800

 acagtatgga atatggactt agttacagtg tcatttcata cctcaaaaaa 1850

 ctgagtcaac aggccaaaat agaatctgat cgagtcattg gatctgtagg 1900

 caaaaaagta gtacaggaga ctggaataaa agtccggagc cgatcacatg 1950

 gtttatcaat ggcatatagg aaagattttc aacaactcct ccagggaatt 2000

 tcagaggatg tccctcacag actgctagac cttaatatga aggaatacac 2050

 tgggttccaa gttgctttgc tgaataagga tttgaagcca cagacattta 2100

 gaaatgctta tgacatacca agacgaaatc ttttggatca cttaacaaga 2150

 atgagatcta atcttttgaa gagcactcgc agatttctga aaggacagga 2200

 cgaagatcaa gtgcacagtg ttcctatagc acaaatgggg aactaccagg 2250

 aatacctcaa gcaagtacct tctccactaa gagaacttga tcctgatcag 2300

 ccacgaaggt tgcatacatt tggcaacccc tttaagctgg ataagaaggg 2350

 tatgatgata gatgaagcag atgaatttgt ggctggacct caaaataaac 2400

 ataaacgacc cggagaacca aatatgcaag ggatccctaa aagacgtcgg 2450

 tgtatgtctc cactactaag aggcagacag cagaatcctg ttgtaaacaa 2500

 tcatattggg ggaaaaggac cacctgcacc tacaactcaa gcacagccag 2550

 atcttattaa acctcttcct cttcataaaa tttcagaaac cactaatgat 2600

 tcgataatac atgatgtggt tgaaaatcat gttgcagacc aactttcatc 2650

 agacattaca ccaaatgcta tggatacgga attttcagca tcttctccag 2700

 ccagtttact ggaacggcca accaatcata tggaggctct tggtcatgac 2750

 catttaggaa ccaatgacct cactgttggt ggatttttag aaaatcatga 2800

 ggagccaaga gataaagaac aatgtgctga agagaacata ccagcatctt 2850

 cactcaacaa aggaaagaaa ttgatgcatt gcagaagcca tgaagaggtc 2900

 aatactgaac taaaagcaca aataatgaaa gagatccgaa agccaggaag 2950

 aaaatatgaa agaatcttca ctttactgaa gcatgtgcaa ggcagtttac 3000

 aaacaagact aatattttta caaaatgtca ttaaagaagc atcaaggttt 3050

 aaaaaacgaa tgctaataga acaactggag aacttcttgg atgaaattca 3100

 tcgaagagcc aatcagatca accatattaa tagcaattaa aagaaaatag 3150

 aatgtggcca cttatttcac tatcttcttc aaatacaaag taaataacaa 3200

 gactgttgtg atcttgcatt cattttctga catgcattgt tggctatttg 3250

 aaatactaaa agcaaatcta cagatccttt ttccatcatt ttacagtgac 3300

 cttttcttca ttttggttta tttttgtaat gtgaaaagta tcactctaaa 3350

 aaacattttt aatttaacaa actaaaaata ttcctccaaa tctcttgctt 3400

 gtcattgact cttgcgtgtc aatttccctc aggttctatt ttcttaaacc 3450

 aacctttaaa attgtcacct ctgttaaggt tgaactttgc caaaaaaaaa 3500

 agaagttact ttgtaatttt tggggaaaaa agcacataca ttaaaactag 3550

 gtaatgtttt gtatatacag ttattttgga tatattattg taagttgtac 3600

 aaatgtattt tgaagaatat ttaagaaaag cacttttgtt attccatcaa 3650

 taaatgctct attttaaaaa aaaaaaaaaa aaaaaaaaaa 3690

<210> 5764
<211> 887
<212> PRT
<213> Homo sapien

<400> 5764
 Met Pro Ile Leu Leu Phe Leu Ile Asp Thr Ser Ala Ser Met Asn
   1               5                  10                  15

 Gln Arg Ser His Leu Gly Thr Thr Tyr Leu Asp Thr Ala Lys Gly
                  20                  25                  30

 Ala Val Glu Thr Phe Met Lys Leu Arg Ala Arg Asp Pro Ala Ser
                  35                  40                  45

 Arg Gly Asp Arg Tyr Met Leu Val Thr Phe Glu Glu Pro Pro Tyr
                  50                  55                  60

 Ala Ile Lys Ala Gly Trp Lys Glu Asn His Ala Thr Phe Met Asn
                  65                  70                  75

 Glu Leu Lys Asn Leu Gln Ala Glu Gly Leu Thr Thr Leu Gly Gln
                  80                  85                  90

 Ser Leu Arg Thr Ala Phe Asp Leu Leu Asn Leu Asn Arg Leu Val
                  95                 100                 105

 Thr Gly Ile Asp Asn Tyr Gly Gln Gly Arg Asn Pro Phe Phe Leu
                 110                 115                 120

 Glu Pro Ala Ile Ile Ile Thr Ile Thr Asp Gly Ser Lys Leu Thr
                 125                 130                 135

 Thr Thr Ser Gly Val Gln Asp Glu Leu His Leu Pro Leu Asn Ser
                 140                 145                 150

 Pro Leu Pro Gly Ser Glu Leu Thr Lys Glu Pro Phe Arg Trp Asp
                 155                 160                 165

 Gln Arg Leu Phe Ala Leu Val Leu Arg Leu Pro Gly Thr Met Ser
                 170                 175                 180

 Val Glu Ser Glu Gln Leu Thr Gly Val Pro Leu Asp Asp Ser Ala
                 185                 190                 195

 Ile Thr Pro Met Cys Glu Val Thr Gly Gly Arg Ser Tyr Ser Val
                 200                 205                 210

 Cys Ser Pro Arg Met Leu Asn Gln Cys Leu Glu Ser Leu Val Gln
                 215                 220                 225

 Lys Val Gln Ser Gly Val Val Ile Asn Phe Glu Lys Ala Gly Pro
                 230                 235                 240

 Asp Pro Ser Pro Val Glu Asp Gly Gln Pro Asp Ile Ser Arg Pro
                 245                 250                 255

 Phe Gly Ser Gln Pro Trp His Ser Cys His Lys Leu Ile Tyr Val
                 260                 265                 270

 Arg Pro Asn Pro Lys Thr Gly Val Pro Ile Gly His Trp Pro Val
                 275                 280                 285

 Pro Glu Ser Phe Trp Pro Asp Gln Asn Ser Pro Thr Leu Pro Pro
                 290                 295                 300

 Arg Thr Ser His Pro Val Val Lys Phe Ser Cys Thr Asp Cys Glu
                 305                 310                 315

 Pro Met Val Ile Asp Lys Leu Pro Phe Asp Lys Tyr Glu Leu Glu
                 320                 325                 330

 Pro Ser Pro Leu Thr Gln Phe Ile Leu Glu Arg Lys Ser Pro Gln
                 335                 340                 345

 Thr Cys Trp Gln Val Tyr Val Ser Asn Ser Ala Lys Tyr Ser Glu
                 350                 355                 360

 Leu Gly His Pro Phe Gly Tyr Leu Lys Ala Ser Thr Ala Leu Asn
                 365                 370                 375

 Cys Val Asn Leu Phe Val Met Pro Tyr Asn Tyr Pro Val Leu Leu
                 380                 385                 390

 Pro Leu Leu Asp Asp Leu Phe Lys Val His Lys Ala Lys Pro Thr
                 395                 400                 405

 Leu Lys Trp Arg Gln Ser Phe Glu Ser Tyr Leu Lys Thr Met Pro
                 410                 415                 420

 Pro Tyr Tyr Leu Gly Pro Leu Lys Lys Ala Val Arg Met Met Gly
                 425                 430                 435

 Ala Pro Asn Leu Ile Ala Asp Ser Met Glu Tyr Gly Leu Ser Tyr
                 440                 445                 450

 Ser Val Ile Ser Tyr Leu Lys Lys Leu Ser Gln Gln Ala Lys Ile
                 455                 460                 465

 Glu Ser Asp Arg Val Ile Gly Ser Val Gly Lys Lys Val Val Gln
                 470                 475                 480

 Glu Thr Gly Ile Lys Val Arg Ser Arg Ser His Gly Leu Ser Met
                 485                 490                 495

 Ala Tyr Arg Lys Asp Phe Gln Gln Leu Leu Gln Gly Ile Ser Glu
                 500                 505                 510

 Asp Val Pro His Arg Leu Leu Asp Leu Asn Met Lys Glu Tyr Thr
                 515                 520                 525

 Gly Phe Gln Val Ala Leu Leu Asn Lys Asp Leu Lys Pro Gln Thr
                 530                 535                 540

 Phe Arg Asn Ala Tyr Asp Ile Pro Arg Arg Asn Leu Leu Asp His
                 545                 550                 555

 Leu Thr Arg Met Arg Ser Asn Leu Leu Lys Ser Thr Arg Arg Phe
                 560                 565                 570

 Leu Lys Gly Gln Asp Glu Asp Gln Val His Ser Val Pro Ile Ala
                 575                 580                 585

 Gln Met Gly Asn Tyr Gln Glu Tyr Leu Lys Gln Val Pro Ser Pro
                 590                 595                 600

 Leu Arg Glu Leu Asp Pro Asp Gln Pro Arg Arg Leu His Thr Phe
                 605                 610                 615

 Gly Asn Pro Phe Lys Leu Asp Lys Lys Gly Met Met Ile Asp Glu
                 620                 625                 630

 Ala Asp Glu Phe Val Ala Gly Pro Gln Asn Lys His Lys Arg Pro
                 635                 640                 645

 Gly Glu Pro Asn Met Gln Gly Ile Pro Lys Arg Arg Arg Cys Met
                 650                 655                 660

 Ser Pro Leu Leu Arg Gly Arg Gln Gln Asn Pro Val Val Asn Asn
                 665                 670                 675

 His Ile Gly Gly Lys Gly Pro Pro Ala Pro Thr Thr Gln Ala Gln
                 680                 685                 690

 Pro Asp Leu Ile Lys Pro Leu Pro Leu His Lys Ile Ser Glu Thr
                 695                 700                 705

 Thr Asn Asp Ser Ile Ile His Asp Val Val Glu Asn His Val Ala
                 710                 715                 720

 Asp Gln Leu Ser Ser Asp Ile Thr Pro Asn Ala Met Asp Thr Glu
                 725                 730                 735

 Phe Ser Ala Ser Ser Pro Ala Ser Leu Leu Glu Arg Pro Thr Asn
                 740                 745                 750

 His Met Glu Ala Leu Gly His Asp His Leu Gly Thr Asn Asp Leu
                 755                 760                 765

 Thr Val Gly Gly Phe Leu Glu Asn His Glu Glu Pro Arg Asp Lys
                 770                 775                 780

 Glu Gln Cys Ala Glu Glu Asn Ile Pro Ala Ser Ser Leu Asn Lys
                 785                 790                 795

 Gly Lys Lys Leu Met His Cys Arg Ser His Glu Glu Val Asn Thr
                 800                 805                 810

 Glu Leu Lys Ala Gln Ile Met Lys Glu Ile Arg Lys Pro Gly Arg
                 815                 820                 825

 Lys Tyr Glu Arg Ile Phe Thr Leu Leu Lys His Val Gln Gly Ser
                 830                 835                 840

 Leu Gln Thr Arg Leu Ile Phe Leu Gln Asn Val Ile Lys Glu Ala
                 845                 850                 855

 Ser Arg Phe Lys Lys Arg Met Leu Ile Glu Gln Leu Glu Asn Phe
                 860                 865                 870

 Leu Asp Glu Ile His Arg Arg Ala Asn Gln Ile Asn His Ile Asn
                 875                 880                 885

 Ser Asn


<210> 5765
<211> 1330
<212> DNA
<213> Homo sapien

<400> 5765
 gcggacgcgg ggcgccagca ggtggcgctg gacgcgcaac ggacaaggag 50

 gcggggcctg cagctggctt ggaggctccg cgctctggag gctcaggcgc 100

 cgcgtggggc ccgcacctct gggcagcagc ggcagccgag actcacggtc 150

 aagctaaggc gaagagtggg tggctgaagc catactattt tatagaatta 200

 atggaaagca gaaaagacat cacaaaccaa gaagaacttt ggaaaatgaa 250

 gcctaggaga aatttagaag aagacgatta tttgcataag gacacgggag 300

 agaccagcat gctaaaaaga cctgtgcttt tgcatttgca ccaaacagcc 350

 catgctgatg aatttgactg cccttcagaa cttcagcaca cacaggaact 400

 ctttccacag tggcacttgc caattaaaat agctgctatt atagcatctc 450

 tgacttttct ttacactctt ctgagggaag taattcaccc tttagcaact 500

 tcccatcaac aatattttta taaaattcca atcctggtca tcaacaaagt 550

 cttgccaatg gtttccatca ctctcttggc attggtttac ctgccaggtg 600

 tgatagcagc aattgtccaa cttcataatg gaaccaagta taagaagttt 650

 ccacattggt tggataagtg gatgttaaca agaaagcagt ttgggcttct 700

 cagtttcttt tttgctgtac tgcatgcaat ttatagtctg tcttacccaa 750

 tgaggcgatc ctacagatac aagttgctaa actgggcata tcaacaggtc 800

 caacaaaata aagaagatgc ctggattgag catgatgttt ggagaatgga 850

 gatttatgtg tctctgggaa ttgtgggatt ggcaatactg gctctgttgg 900

 ctgtgacatc tattccatct gtgagtgact ctttgacatg gagagaattt 950

 cactatattc agagcaagct aggaattgtt tcccttctac tgggcacaat 1000

 acacgcattg atttttgcct ggaataagtg gatagatata aaacaatttg 1050

 tatggtatac acctccaact tttatgatag ctgttttcct tccaattgtt 1100

 gtcctgatat ttaaaagcat actattcctg ccatgcttga ggaagaagat 1150

 actgaagatt agacatggtt gggaagacgt caccaaaatt aacaaaactg 1200

 agatatgttc ccagttgtag aattactgtt tacacacatt tttgttcaat 1250

 attgatatat tttatcacca acatttcaag tttgtatttg ttaataaaat 1300

 gattattcaa ggaaaaaaaa aaaaaaaaaa 1330

<210> 5766
<211> 339
<212> PRT
<213> Homo sapien

<400> 5766
 Met Glu Ser Arg Lys Asp Ile Thr Asn Gln Glu Glu Leu Trp Lys
   1               5                  10                  15

 Met Lys Pro Arg Arg Asn Leu Glu Glu Asp Asp Tyr Leu His Lys
                  20                  25                  30

 Asp Thr Gly Glu Thr Ser Met Leu Lys Arg Pro Val Leu Leu His
                  35                  40                  45

 Leu His Gln Thr Ala His Ala Asp Glu Phe Asp Cys Pro Ser Glu
                  50                  55                  60

 Leu Gln His Thr Gln Glu Leu Phe Pro Gln Trp His Leu Pro Ile
                  65                  70                  75

 Lys Ile Ala Ala Ile Ile Ala Ser Leu Thr Phe Leu Tyr Thr Leu
                  80                  85                  90

 Leu Arg Glu Val Ile His Pro Leu Ala Thr Ser His Gln Gln Tyr
                  95                 100                 105

 Phe Tyr Lys Ile Pro Ile Leu Val Ile Asn Lys Val Leu Pro Met
                 110                 115                 120

 Val Ser Ile Thr Leu Leu Ala Leu Val Tyr Leu Pro Gly Val Ile
                 125                 130                 135

 Ala Ala Ile Val Gln Leu His Asn Gly Thr Lys Tyr Lys Lys Phe
                 140                 145                 150

 Pro His Trp Leu Asp Lys Trp Met Leu Thr Arg Lys Gln Phe Gly
                 155                 160                 165

 Leu Leu Ser Phe Phe Phe Ala Val Leu His Ala Ile Tyr Ser Leu
                 170                 175                 180

 Ser Tyr Pro Met Arg Arg Ser Tyr Arg Tyr Lys Leu Leu Asn Trp
                 185                 190                 195

 Ala Tyr Gln Gln Val Gln Gln Asn Lys Glu Asp Ala Trp Ile Glu
                 200                 205                 210

 His Asp Val Trp Arg Met Glu Ile Tyr Val Ser Leu Gly Ile Val
                 215                 220                 225

 Gly Leu Ala Ile Leu Ala Leu Leu Ala Val Thr Ser Ile Pro Ser
                 230                 235                 240

 Val Ser Asp Ser Leu Thr Trp Arg Glu Phe His Tyr Ile Gln Ser
                 245                 250                 255

 Lys Leu Gly Ile Val Ser Leu Leu Leu Gly Thr Ile His Ala Leu
                 260                 265                 270

 Ile Phe Ala Trp Asn Lys Trp Ile Asp Ile Lys Gln Phe Val Trp
                 275                 280                 285

 Tyr Thr Pro Pro Thr Phe Met Ile Ala Val Phe Leu Pro Ile Val
                 290                 295                 300

 Val Leu Ile Phe Lys Ser Ile Leu Phe Leu Pro Cys Leu Arg Lys
                 305                 310                 315

 Lys Ile Leu Lys Ile Arg His Gly Trp Glu Asp Val Thr Lys Ile
                 320                 325                 330

 Asn Lys Thr Glu Ile Cys Ser Gln Leu
                 335

<210> 5767
<211> 2718
<212> DNA
<213> Homo sapien

<400> 5767
 ccgccatggg gtccctgttc cggagcgaga ccatgtgcct ggcgcagctc 50

 ttcctgcagt cgggcacggc ctacgagtgc ctcagcgccc tgggcgagaa 100

 aggcctggtc cagttccgag acctcaacca gaacgtaagt tctttccaaa 150

 gaaaatttgt tggtgaggtg aagaggtgtg aagagctaga gcgaatattg 200

 gtgtatttgg tacaggaaat taatagagct gatattcccc ttcctgaagg 250

 agaggccagc cctcctgcgc cacccctgaa acaggttcta gaaatgcagg 300

 agcagttgca gaagctcgag gttgaactga gagaagtcac taagaacaag 350

 gagaaactga ggaaaaactt gctggaactg atagagtaca ctcacatgct 400

 gagagtgaca aagacctttg tgaaacgcaa cgttgagttt gaacccactt 450

 atgaagaatt cccttcctta gagagcgatt ctttgttgga ttacagctgt 500

 atgcagaggc tgggagcaaa actgggattt gtgtctggcc taattaacca 550

 aggaaaagtg gaagcatttg aaaaaatgtt gtggagagtc tgcaaagggt 600

 acaccatcgt gtcctatgca gaactggatg aatcccttga agaccctgaa 650

 acaggggaag tcataaaatg gtatgtcttt ttaatatcct tttggggaga 700

 gcagattggc cacaaggtta agaagatatg tgattgctac cactgccacg 750

 tgtaccccta tccaaacaca gccgaggagc ggagggagat ccaggagggg 800

 ctgaacaccc gcatccagga tctctacact gtactgcaca aaaccgagga 850

 ctatttgagg caagtgctat gtaaagccgc cgagtctgtc tacagccgtg 900

 tgatccaggt gaagaaaatg aaggccatct atcacatgct gaacatgtgc 950

 agctttgacg tgaccaacaa gtgcctcatt gctgaagtct ggtgtcccga 1000

 ggcggatctg caggacctgc gccgggcact ggaggagggc tcgagagaga 1050

 gtggtgctac aatcccctca ttcatgaata taatccccac aaaagaaaca 1100

 ccccccactc ggatccgcac caacaaattc accgagggat ttcagaacat 1150

 cgtggatgct tatggagtcg gaagctacag agaagtcaat ccagctctct 1200

 ttaccatcat caccttcccg tttttatttg ctgtgatgtt tggagacttc 1250

 ggacatggct ttgtgatgtt tttatttgcc ctcttgtggg tgttaaatga 1300

 aaatcatccc agactaaatc agtcacaaga gatcatgagg atgtttttta 1350

 atggccggta catcctcctg ctgatggggc tgttctcagt gtacactggc 1400

 ctcatctaca acgactgctt ttcaaagtca gtcaacctgt tcggctctgg 1450

 gtggaacgtg tcggccatgt acagctccag ccacccaccc gcagagcata 1500

 agaagatggt gctttggaac gacagcgtcg ttagacacaa cagcattttg 1550

 cagctggatc caagcattcc tggagtgttc cgaggccctt atccccttgg 1600

 cattgatcct atttggaact tggccacaaa tcgcctcact tttctaaact 1650

 ctttcaaaat gaaaatgtcc gtgattttag gaatcattca tatgactttt 1700

 ggagtcattc tgggaatatt taaccacttg cacttcagga agaagttcaa 1750

 catttacctg gtttccatcc cggaacttct cttcatgctc tgtatctttg 1800

 gataccttat atttatgatt ttctacaagt ggctggtttt ttcagcagaa 1850

 acctccagag ttgctcccag cattctgatt gaatttatta acatgttttt 1900

 attcccagcc agtaaaacaa gtggccttta cacagggcag gagtatgtcc 1950

 agagagtgct gctggttgtc acagcattgt ctgtccctgt cctcttcttg 2000

 ggaaagccac tgtttttgtt gtggcttcac aatgggcgta gttgcttcgg 2050

 ggtgaaccgg agtggctaca cacttataag gaaagatagt gaggaagaag 2100

 tttcattgct gggaagccaa gatatagaag agggaaatca ccaggtggaa 2150

 gatggatgta gagaaatggc gtgtgaagag tttaattttg gagaaatatt 2200

 aatgacccaa gtaatccatt ccatcgagta ctgtctggga tgcatctcca 2250

 acaccgcctc ctacctgagg ctctgggcgc ttagcctggc tcacgcacag 2300

 ttgtctgatg tcctgtgggc catgctgatg cgcgtgggcc tccgcgttga 2350

 caccacctat ggcgtcttgc tactgctccc ggttatcgcg ctctttgcag 2400

 ttttgaccat tttcatcctt ctgatcatgg aagggctttc tgcgtttctt 2450

 cacgccatac gcctccactg ggtagaattt cagaacaaat tctacgttgg 2500

 tgcaggcacc aaatttgttc ctttctcatt cagtctactt tcatcaaagt 2550

 tcaataacga cgacagtgtg gcatgatcat attgctgtaa ccaacaagct 2600

 ttcagattta tggagaatga ccatgttata gactttcact tatgtcagat 2650

 ttatgatagg aaaaattcca tcttcattac tgccttatga catagccaaa 2700

 taattctgta agatatac 2718

<210> 5768
<211> 856
<212> PRT
<213> Homo sapien

<400> 5768
 Met Gly Ser Leu Phe Arg Ser Glu Thr Met Cys Leu Ala Gln Leu
   1               5                  10                  15

 Phe Leu Gln Ser Gly Thr Ala Tyr Glu Cys Leu Ser Ala Leu Gly
                  20                  25                  30

 Glu Lys Gly Leu Val Gln Phe Arg Asp Leu Asn Gln Asn Val Ser
                  35                  40                  45

 Ser Phe Gln Arg Lys Phe Val Gly Glu Val Lys Arg Cys Glu Glu
                  50                  55                  60

 Leu Glu Arg Ile Leu Val Tyr Leu Val Gln Glu Ile Asn Arg Ala
                  65                  70                  75

 Asp Ile Pro Leu Pro Glu Gly Glu Ala Ser Pro Pro Ala Pro Pro
                  80                  85                  90

 Leu Lys Gln Val Leu Glu Met Gln Glu Gln Leu Gln Lys Leu Glu
                  95                 100                 105

 Val Glu Leu Arg Glu Val Thr Lys Asn Lys Glu Lys Leu Arg Lys
                 110                 115                 120

 Asn Leu Leu Glu Leu Ile Glu Tyr Thr His Met Leu Arg Val Thr
                 125                 130                 135

 Lys Thr Phe Val Lys Arg Asn Val Glu Phe Glu Pro Thr Tyr Glu
                 140                 145                 150

 Glu Phe Pro Ser Leu Glu Ser Asp Ser Leu Leu Asp Tyr Ser Cys
                 155                 160                 165

 Met Gln Arg Leu Gly Ala Lys Leu Gly Phe Val Ser Gly Leu Ile
                 170                 175                 180

 Asn Gln Gly Lys Val Glu Ala Phe Glu Lys Met Leu Trp Arg Val
                 185                 190                 195

 Cys Lys Gly Tyr Thr Ile Val Ser Tyr Ala Glu Leu Asp Glu Ser
                 200                 205                 210

 Leu Glu Asp Pro Glu Thr Gly Glu Val Ile Lys Trp Tyr Val Phe
                 215                 220                 225

 Leu Ile Ser Phe Trp Gly Glu Gln Ile Gly His Lys Val Lys Lys
                 230                 235                 240

 Ile Cys Asp Cys Tyr His Cys His Val Tyr Pro Tyr Pro Asn Thr
                 245                 250                 255

 Ala Glu Glu Arg Arg Glu Ile Gln Glu Gly Leu Asn Thr Arg Ile
                 260                 265                 270

 Gln Asp Leu Tyr Thr Val Leu His Lys Thr Glu Asp Tyr Leu Arg
                 275                 280                 285

 Gln Val Leu Cys Lys Ala Ala Glu Ser Val Tyr Ser Arg Val Ile
                 290                 295                 300

 Gln Val Lys Lys Met Lys Ala Ile Tyr His Met Leu Asn Met Cys
                 305                 310                 315

 Ser Phe Asp Val Thr Asn Lys Cys Leu Ile Ala Glu Val Trp Cys
                 320                 325                 330

 Pro Glu Ala Asp Leu Gln Asp Leu Arg Arg Ala Leu Glu Glu Gly
                 335                 340                 345

 Ser Arg Glu Ser Gly Ala Thr Ile Pro Ser Phe Met Asn Ile Ile
                 350                 355                 360

 Pro Thr Lys Glu Thr Pro Pro Thr Arg Ile Arg Thr Asn Lys Phe
                 365                 370                 375

 Thr Glu Gly Phe Gln Asn Ile Val Asp Ala Tyr Gly Val Gly Ser
                 380                 385                 390

 Tyr Arg Glu Val Asn Pro Ala Leu Phe Thr Ile Ile Thr Phe Pro
                 395                 400                 405

 Phe Leu Phe Ala Val Met Phe Gly Asp Phe Gly His Gly Phe Val
                 410                 415                 420

 Met Phe Leu Phe Ala Leu Leu Trp Val Leu Asn Glu Asn His Pro
                 425                 430                 435

 Arg Leu Asn Gln Ser Gln Glu Ile Met Arg Met Phe Phe Asn Gly
                 440                 445                 450

 Arg Tyr Ile Leu Leu Leu Met Gly Leu Phe Ser Val Tyr Thr Gly
                 455                 460                 465

 Leu Ile Tyr Asn Asp Cys Phe Ser Lys Ser Val Asn Leu Phe Gly
                 470                 475                 480

 Ser Gly Trp Asn Val Ser Ala Met Tyr Ser Ser Ser His Pro Pro
                 485                 490                 495

 Ala Glu His Lys Lys Met Val Leu Trp Asn Asp Ser Val Val Arg
                 500                 505                 510

 His Asn Ser Ile Leu Gln Leu Asp Pro Ser Ile Pro Gly Val Phe
                 515                 520                 525

 Arg Gly Pro Tyr Pro Leu Gly Ile Asp Pro Ile Trp Asn Leu Ala
                 530                 535                 540

 Thr Asn Arg Leu Thr Phe Leu Asn Ser Phe Lys Met Lys Met Ser
                 545                 550                 555

 Val Ile Leu Gly Ile Ile His Met Thr Phe Gly Val Ile Leu Gly
                 560                 565                 570

 Ile Phe Asn His Leu His Phe Arg Lys Lys Phe Asn Ile Tyr Leu
                 575                 580                 585

 Val Ser Ile Pro Glu Leu Leu Phe Met Leu Cys Ile Phe Gly Tyr
                 590                 595                 600

 Leu Ile Phe Met Ile Phe Tyr Lys Trp Leu Val Phe Ser Ala Glu
                 605                 610                 615

 Thr Ser Arg Val Ala Pro Ser Ile Leu Ile Glu Phe Ile Asn Met
                 620                 625                 630

 Phe Leu Phe Pro Ala Ser Lys Thr Ser Gly Leu Tyr Thr Gly Gln
                 635                 640                 645

 Glu Tyr Val Gln Arg Val Leu Leu Val Val Thr Ala Leu Ser Val
                 650                 655                 660

 Pro Val Leu Phe Leu Gly Lys Pro Leu Phe Leu Leu Trp Leu His
                 665                 670                 675

 Asn Gly Arg Ser Cys Phe Gly Val Asn Arg Ser Gly Tyr Thr Leu
                 680                 685                 690

 Ile Arg Lys Asp Ser Glu Glu Glu Val Ser Leu Leu Gly Ser Gln
                 695                 700                 705

 Asp Ile Glu Glu Gly Asn His Gln Val Glu Asp Gly Cys Arg Glu
                 710                 715                 720

 Met Ala Cys Glu Glu Phe Asn Phe Gly Glu Ile Leu Met Thr Gln
                 725                 730                 735

 Val Ile His Ser Ile Glu Tyr Cys Leu Gly Cys Ile Ser Asn Thr
                 740                 745                 750

 Ala Ser Tyr Leu Arg Leu Trp Ala Leu Ser Leu Ala His Ala Gln
                 755                 760                 765

 Leu Ser Asp Val Leu Trp Ala Met Leu Met Arg Val Gly Leu Arg
                 770                 775                 780

 Val Asp Thr Thr Tyr Gly Val Leu Leu Leu Leu Pro Val Ile Ala
                 785                 790                 795

 Leu Phe Ala Val Leu Thr Ile Phe Ile Leu Leu Ile Met Glu Gly
                 800                 805                 810

 Leu Ser Ala Phe Leu His Ala Ile Arg Leu His Trp Val Glu Phe
                 815                 820                 825

 Gln Asn Lys Phe Tyr Val Gly Ala Gly Thr Lys Phe Val Pro Phe
                 830                 835                 840

 Ser Phe Ser Leu Leu Ser Ser Lys Phe Asn Asn Asp Asp Ser Val
                 845                 850                 855

 Ala


<210> 5769
<211> 853
<212> DNA
<213> Homo sapien

<400> 5769
 cctgggccct cctgctcctt gcagccatgc tcctgggcaa cccagcccct 50

 gcctccgcat ctgcgtggtg aaggccattg gcctcatcgg tggatctgcg 100

 tttcctcggg cccacactgt ctaggattgt gcggggctgg tgagagaaca 150

 agatctcttc cgtgttcaag gcagacttcc tgccccctgc accctgctct 200

 ctcccgggcc ttgaggtcag tgtgagcccc aagggcaaga acacttctgg 250

 aagggagagt ggatttggct gggcctctgg atggaaggtc tggtcttctc 300

 tcgtctgagc cctgagtact acgacccggc aagagcccac ctgcgtgatg 350

 gggagaaatc ctgcccgtgc gggcaggagg gcccccaggg tgacctgttg 400

 accaaaacac aggagctggg ccgtgactac aggacctgtc tgacgatagt 450

 ccaaaaactg aagaagatgg tggataagcc cacccagaga agtgtttcca 500

 atgctgcgac ccgggtgtgt aggacgggga ggtcacgatg gcgcgacgtc 550

 tgcagaaatt tcatgaggag gtatcagtct agagttatcc aaggcctcgt 600

 ggccggagaa actgcccagc agatctgtga ggacctcagg ttgtgtatac 650

 cttctacagg tcccctctga gccctctcac cttgtcctgt ggaagaagca 700

 caggctcctg tcctcagatc ccgggaacgt cagcaacctc tgccggctcc 750

 tcgcttcctc gatccagaat ccactctcca gtctccctcc cctgactccc 800

 tctgctgtcc tcccctctca ggggaataaa gtgtcaagca agattttagc 850

 cgc 853

<210> 5770
<211> 129
<212> PRT
<213> Homo sapien

<400> 5770
 Met Glu Gly Leu Val Phe Ser Arg Leu Ser Pro Glu Tyr Tyr Asp
   1               5                  10                  15

 Pro Ala Arg Ala His Leu Arg Asp Gly Glu Lys Ser Cys Pro Cys
                  20                  25                  30

 Gly Gln Glu Gly Pro Gln Gly Asp Leu Leu Thr Lys Thr Gln Glu
                  35                  40                  45

 Leu Gly Arg Asp Tyr Arg Thr Cys Leu Thr Ile Val Gln Lys Leu
                  50                  55                  60

 Lys Lys Met Val Asp Lys Pro Thr Gln Arg Ser Val Ser Asn Ala
                  65                  70                  75

 Ala Thr Arg Val Cys Arg Thr Gly Arg Ser Arg Trp Arg Asp Val
                  80                  85                  90

 Cys Arg Asn Phe Met Arg Arg Tyr Gln Ser Arg Val Ile Gln Gly
                  95                 100                 105

 Leu Val Ala Gly Glu Thr Ala Gln Gln Ile Cys Glu Asp Leu Arg
                 110                 115                 120

 Leu Cys Ile Pro Ser Thr Gly Pro Leu
                 125

<210> 5771
<211> 2957
<212> DNA
<213> Homo sapien

<400> 5771
 gccagtcacc ttcagtttct ggagctggcc gtcaacatgt cctttcctaa 50

 ggcgcccttg aaacgattca atgacccttc tggttgtgca ccatctccag 100

 gtgcttatga tgttaaaact ttagaagtat tgaaaggacc agtatccttt 150

 cagaaatcac aaagatttaa acaacaaaaa gaatctaaac aaaatcttaa 200

 tgttgacaaa gatactacct tgcctgcttc agctagaaaa gttaagtctt 250

 cggaatcaaa gattcgtgtt cttctacagg aacgtggtgc ccaggacagc 300

 cggatccagg atctggaaac tgagttggaa aagatggaag caaggctaaa 350

 tgctgcacta agggaaaaaa catctctctc tgcaaataat gctacactgg 400

 aaaaacaact tattgaattg accaggacta atgaactact aaaatctaag 450

 ttttctgaaa atggtaacca gaagaatttg agaattctaa gcttggagtt 500

 gatgaaactt agaaacaaaa gagaaacaaa gatgaggggt atgatggcta 550

 agcaagaagg catggagatg aagctgcagg tcacccaaag gagtctcgaa 600

 gagtctcaag ggaaaatagc ccaactggag ggaaaacttg tttcaataga 650

 gaaagaaaag attgatgaaa aatctgaaac agaaaaactc ttggaataca 700

 tcgaagaaat tagttgtgct tcagatcaag tggaaaaata caagctagat 750

 attgcccagt tagaagaaaa tttgaaagag aagaatgatg aaattttaag 800

 ccttaagcag tctcttgagg agaatattgt tatattatct aaacaagtag 850

 aagatctaaa tgtgaaatgt cagctgcttg aaaaagaaaa agaagaccat 900

 gtcaacagga atagagaaca caacgaaaat ctaaatgcag agatgcaaaa 950

 cttaaaacag aagtttattc ttgaacaaca ggaacgtgaa aagcttcaac 1000

 aaaaagaatt acaaattgat tcacttctgc aacaagagaa agaattatct 1050

 tcgagtcttc atcagaagct ctgttctttt caagaggaaa tggttaaaga 1100

 gaagaatctg tttgaggaag aattaaagca aacactggat gagcttgata 1150

 aattacagca aaaggaggaa caagctgaaa ggctggtcaa gcaattggaa 1200

 gaggaagcaa aatctagagc tgaagaatta aaactcctag aagaaaagct 1250

 gaaagggaag gaggctgaac tggagaaaag tagtgctgct catacccagg 1300

 ccaccctgct tttgcaggaa aagtatgaca gtatggtgca aagccttgaa 1350

 gatgttactg ctcaatttga aagctataaa gcgttaacag ccagtgagat 1400

 agaagatctt aagctggaga actcatcatt acaggaaaaa gcggccaagg 1450

 ctgggaaaaa tgcagaggat gttcagcatc agattttggc aactgagagc 1500

 tcaaatcaag aatatgtaag gatgcttcta gatctgcaga ccaagtcagc 1550

 actaaaggaa acagaaatta aagaaatcac agtttctttt cttcaaaaaa 1600

 taactgattt gcagaaccaa ctcaagcaac aggaggaaga ctttagaaaa 1650

 cagctggaag atgaagaagg aagaaaagct gaaaaagaaa atacaacagc 1700

 agaattaact gaagaaatta acaagtggcg tctcctctat gaagaactat 1750

 ataataaaac aaaacctttt cagctacaac tagatgcttt tgaagtagaa 1800

 aaacaggcat tgttgaatga acatggtgca gctcaggaac agctaaataa 1850

 aataagagat tcatatgcta aattattggg tcatcagaat ttgaaacaaa 1900

 aaatcaagca tgttgtgaag ttgaaagatg aaaatagcca actcaaatcg 1950

 gaagtatcaa aactccgctg tcagcttgct aaaaaaaaac aaagtgagac 2000

 aaaacttcaa gaggaattga ataaagttct aggtatcaaa cactttgatc 2050

 cttcaaaggc ttttcatcat gaaagtaaag aaaattttgc cctgaagacc 2100

 ccattaaaag aaggcaatac aaactgttac cgagctccta tggagtgtca 2150

 agaatcatgg aagtaaacat ctgagaaacc tgttgaagat tatttcattc 2200

 gtcttgttgt tattgatgtt gctgttatta tatttgacat gggtatttta 2250

 taatgttgta tttaatttta actgccaatc cttaaatatg tgaaaggaac 2300

 attttttacc aaagtgtctt ttgacatttt attttttctt gcaaatacct 2350

 cctccctaat gctcaccttt atcacctcat tctgaaccct ttcgctggct 2400

 ttccagctta gaatgcatct catcaactta aaagtcagta tcatattatt 2450

 atcctcctgt tctgaaacct tagtttcaag agtctaaacc ccagattctt 2500

 cagcttgatc ctggaggtct tttctagtct gagcttcttt agctaggcta 2550

 aaacaccttg gcttgttatt gcctctactt tgattctgat aatgctcact 2600

 tggtcctacc tattatcctt ctacttgtcc agttcaaata agaaataagg 2650

 acaagcctaa cttcatagaa acctctctat ttttaatcag ttgtttaata 2700

 atttacaggt tcttaggctc catcctgttt gtatgaaatt ataatctgtg 2750

 gattggcctt taagcctgca ttcttaacaa actcttcagt taattcttag 2800

 atacactaaa aatctgagaa actctacatg taactatttc ttcagagttt 2850

 gtcatatact gcttgtcatc tgcatgtcta ctcagcattt gattaacatt 2900

 tgtgtaatat gaaataaaat tacacagtaa gtcatttaac caaaaaaaaa 2950

 aaaaaaa 2957

<210> 5772
<211> 709
<212> PRT
<213> Homo sapien

<400> 5772
 Met Ser Phe Pro Lys Ala Pro Leu Lys Arg Phe Asn Asp Pro Ser
   1               5                  10                  15

 Gly Cys Ala Pro Ser Pro Gly Ala Tyr Asp Val Lys Thr Leu Glu
                  20                  25                  30

 Val Leu Lys Gly Pro Val Ser Phe Gln Lys Ser Gln Arg Phe Lys
                  35                  40                  45

 Gln Gln Lys Glu Ser Lys Gln Asn Leu Asn Val Asp Lys Asp Thr
                  50                  55                  60

 Thr Leu Pro Ala Ser Ala Arg Lys Val Lys Ser Ser Glu Ser Lys
                  65                  70                  75

 Ile Arg Val Leu Leu Gln Glu Arg Gly Ala Gln Asp Ser Arg Ile
                  80                  85                  90

 Gln Asp Leu Glu Thr Glu Leu Glu Lys Met Glu Ala Arg Leu Asn
                  95                 100                 105

 Ala Ala Leu Arg Glu Lys Thr Ser Leu Ser Ala Asn Asn Ala Thr
                 110                 115                 120

 Leu Glu Lys Gln Leu Ile Glu Leu Thr Arg Thr Asn Glu Leu Leu
                 125                 130                 135

 Lys Ser Lys Phe Ser Glu Asn Gly Asn Gln Lys Asn Leu Arg Ile
                 140                 145                 150

 Leu Ser Leu Glu Leu Met Lys Leu Arg Asn Lys Arg Glu Thr Lys
                 155                 160                 165

 Met Arg Gly Met Met Ala Lys Gln Glu Gly Met Glu Met Lys Leu
                 170                 175                 180

 Gln Val Thr Gln Arg Ser Leu Glu Glu Ser Gln Gly Lys Ile Ala
                 185                 190                 195

 Gln Leu Glu Gly Lys Leu Val Ser Ile Glu Lys Glu Lys Ile Asp
                 200                 205                 210

 Glu Lys Ser Glu Thr Glu Lys Leu Leu Glu Tyr Ile Glu Glu Ile
                 215                 220                 225

 Ser Cys Ala Ser Asp Gln Val Glu Lys Tyr Lys Leu Asp Ile Ala
                 230                 235                 240

 Gln Leu Glu Glu Asn Leu Lys Glu Lys Asn Asp Glu Ile Leu Ser
                 245                 250                 255

 Leu Lys Gln Ser Leu Glu Glu Asn Ile Val Ile Leu Ser Lys Gln
                 260                 265                 270

 Val Glu Asp Leu Asn Val Lys Cys Gln Leu Leu Glu Lys Glu Lys
                 275                 280                 285

 Glu Asp His Val Asn Arg Asn Arg Glu His Asn Glu Asn Leu Asn
                 290                 295                 300

 Ala Glu Met Gln Asn Leu Lys Gln Lys Phe Ile Leu Glu Gln Gln
                 305                 310                 315

 Glu Arg Glu Lys Leu Gln Gln Lys Glu Leu Gln Ile Asp Ser Leu
                 320                 325                 330

 Leu Gln Gln Glu Lys Glu Leu Ser Ser Ser Leu His Gln Lys Leu
                 335                 340                 345

 Cys Ser Phe Gln Glu Glu Met Val Lys Glu Lys Asn Leu Phe Glu
                 350                 355                 360

 Glu Glu Leu Lys Gln Thr Leu Asp Glu Leu Asp Lys Leu Gln Gln
                 365                 370                 375

 Lys Glu Glu Gln Ala Glu Arg Leu Val Lys Gln Leu Glu Glu Glu
                 380                 385                 390

 Ala Lys Ser Arg Ala Glu Glu Leu Lys Leu Leu Glu Glu Lys Leu
                 395                 400                 405

 Lys Gly Lys Glu Ala Glu Leu Glu Lys Ser Ser Ala Ala His Thr
                 410                 415                 420

 Gln Ala Thr Leu Leu Leu Gln Glu Lys Tyr Asp Ser Met Val Gln
                 425                 430                 435

 Ser Leu Glu Asp Val Thr Ala Gln Phe Glu Ser Tyr Lys Ala Leu
                 440                 445                 450

 Thr Ala Ser Glu Ile Glu Asp Leu Lys Leu Glu Asn Ser Ser Leu
                 455                 460                 465

 Gln Glu Lys Ala Ala Lys Ala Gly Lys Asn Ala Glu Asp Val Gln
                 470                 475                 480

 His Gln Ile Leu Ala Thr Glu Ser Ser Asn Gln Glu Tyr Val Arg
                 485                 490                 495

 Met Leu Leu Asp Leu Gln Thr Lys Ser Ala Leu Lys Glu Thr Glu
                 500                 505                 510

 Ile Lys Glu Ile Thr Val Ser Phe Leu Gln Lys Ile Thr Asp Leu
                 515                 520                 525

 Gln Asn Gln Leu Lys Gln Gln Glu Glu Asp Phe Arg Lys Gln Leu
                 530                 535                 540

 Glu Asp Glu Glu Gly Arg Lys Ala Glu Lys Glu Asn Thr Thr Ala
                 545                 550                 555

 Glu Leu Thr Glu Glu Ile Asn Lys Trp Arg Leu Leu Tyr Glu Glu
                 560                 565                 570

 Leu Tyr Asn Lys Thr Lys Pro Phe Gln Leu Gln Leu Asp Ala Phe
                 575                 580                 585

 Glu Val Glu Lys Gln Ala Leu Leu Asn Glu His Gly Ala Ala Gln
                 590                 595                 600

 Glu Gln Leu Asn Lys Ile Arg Asp Ser Tyr Ala Lys Leu Leu Gly
                 605                 610                 615

 His Gln Asn Leu Lys Gln Lys Ile Lys His Val Val Lys Leu Lys
                 620                 625                 630

 Asp Glu Asn Ser Gln Leu Lys Ser Glu Val Ser Lys Leu Arg Cys
                 635                 640                 645

 Gln Leu Ala Lys Lys Lys Gln Ser Glu Thr Lys Leu Gln Glu Glu
                 650                 655                 660

 Leu Asn Lys Val Leu Gly Ile Lys His Phe Asp Pro Ser Lys Ala
                 665                 670                 675

 Phe His His Glu Ser Lys Glu Asn Phe Ala Leu Lys Thr Pro Leu
                 680                 685                 690

 Lys Glu Gly Asn Thr Asn Cys Tyr Arg Ala Pro Met Glu Cys Gln
                 695                 700                 705

 Glu Ser Trp Lys


<210> 5773
<211> 850
<212> DNA
<213> Homo sapien

<400> 5773
 gaattccggc aaaatgcatg acagtaacaa tgtggagaaa gacattacac 50

 catctgaatt gcctgcaaac ccaggttgtc tgcattcaaa agagcattct 100

 attaaagcta ccttaatttg gcgcttattt ttcttaatca tgtttctgac 150

 aatcatagtg tgtggaatgg ttgctgcttt aagcgcaata agagctaact 200

 gccatcaaga gccatcagta tgtcttcaag ctgcatgccc agaaagctgg 250

 attggttttc aaagaaagtg tttctatttt tctgatgaca ccaagaactg 300

 gacatcaagt cagaggtttt gtgactcaca agatgctgat cttgctcagg 350

 ttgaaagctt ccaggaactg aatttcctgt tgagatataa aggcccatct 400

 gatcactgga ttgggctgag cagagaacaa ggccaaccat ggaaatggat 450

 aaatggtact gaatggacaa gacagtttcc tatcctggga gcaggagagt 500

 gtgcctattt gaatgacaaa ggtgccagta gtgccaggca ctacacagag 550

 aggaagtgga tttgttccaa atcagatata catgtctaga tgttacagca 600

 aagccccaac taatctttag aagcatattg gaactgataa ctccatttta 650

 aaatgagcaa agaatttatt tcttatacca acaggtatat gaaaatatgc 700

 tcaatatcac taataactgg gaaaatacaa atcaaaatca tagtaaaata 750

 ttacctgttt tcatggtgct aatattacct gttctcccac tgctaatgac 800

 atacccgaga atgagtaatt tataaataaa agagatttaa ttgaaaaaaa 850

<210> 5774
<211> 191
<212> PRT
<213> Homo sapien

<400> 5774
 Met His Asp Ser Asn Asn Val Glu Lys Asp Ile Thr Pro Ser Glu
   1               5                  10                  15

 Leu Pro Ala Asn Pro Gly Cys Leu His Ser Lys Glu His Ser Ile
                  20                  25                  30

 Lys Ala Thr Leu Ile Trp Arg Leu Phe Phe Leu Ile Met Phe Leu
                  35                  40                  45

 Thr Ile Ile Val Cys Gly Met Val Ala Ala Leu Ser Ala Ile Arg
                  50                  55                  60

 Ala Asn Cys His Gln Glu Pro Ser Val Cys Leu Gln Ala Ala Cys
                  65                  70                  75

 Pro Glu Ser Trp Ile Gly Phe Gln Arg Lys Cys Phe Tyr Phe Ser
                  80                  85                  90

 Asp Asp Thr Lys Asn Trp Thr Ser Ser Gln Arg Phe Cys Asp Ser
                  95                 100                 105

 Gln Asp Ala Asp Leu Ala Gln Val Glu Ser Phe Gln Glu Leu Asn
                 110                 115                 120

 Phe Leu Leu Arg Tyr Lys Gly Pro Ser Asp His Trp Ile Gly Leu
                 125                 130                 135

 Ser Arg Glu Gln Gly Gln Pro Trp Lys Trp Ile Asn Gly Thr Glu
                 140                 145                 150

 Trp Thr Arg Gln Phe Pro Ile Leu Gly Ala Gly Glu Cys Ala Tyr
                 155                 160                 165

 Leu Asn Asp Lys Gly Ala Ser Ser Ala Arg His Tyr Thr Glu Arg
                 170                 175                 180

 Lys Trp Ile Cys Ser Lys Ser Asp Ile His Val
                 185                 190

<210> 5775
<211> 2740
<212> DNA
<213> Homo sapien

<400> 5775
 ggcggcggcg gcggcggcga agaactgttc cttccacctc ttcagccccg 50

 gcaggacggg ggcggccgcc gcgaacccgg ggcggggaca gcacgcagcc 100

 tcgaggcgcg cacccccgcc cggcagcggc cccgacaccc ggggcgagcg 150

 ggaaaacggc aacggcggcg gcggcggcgg cggcggggga aggatgcagg 200

 ggaagaagcc gggcggttcg tcgggcggcg gccggagcgg cgagctgcag 250

 ggggacgagg cgcagaggaa caagaaaaag aaaaagaagg tgtcctgctt 300

 ttccaacatc aagatcttcc tggtgtccga gtgcgccctg atgctggcgc 350

 agggcacggt gggcgcctac ctggtgagcg tcctgaccac cctggagcgt 400

 aggttcaacc tgcagagcgc tgacgtgggt gtgatcgcta gcagcttcga 450

 gatcgggaac ctggcgctca tcctcttcgt gagctacttc ggggcacgcg 500

 ggcaccggcc gcgcctgatc ggctgcggcg gcatcgtcat ggcgctgggc 550

 gcgctgctgt cggcgctgcc cgagttcctg acccaccagt acaagtacga 600

 ggcgggcgag atccgctggg gcgccgaggg ccgcgacgtc tgcgcagcca 650

 acggctcggg cggcgacgag gggcccgacc ccgacctcat ctgccgcaac 700

 cggacggcta ccaacatgat gtacttgctg ctcattgggg cccaggtgct 750

 cctgggcatc ggtgctaccc ctgtgcagcc cctgggcgtc tcctactacg 800

 acgaccacgt gcggaggaag gactcctcgc tctatatagg aatcctgttc 850

 acgatgctgg tatttggacc agcctgcggg tttatcctgg gctctttctg 900

 taccaaaatc tacgtggatg cggtcttcat tgacacaagt aacctggaca 950

 tcactccgga cgacccccgc tggatcggag cctggtgggg tggctttctg 1000

 ctctgcggtg ccttactctt cttctcttcc ctcttgatgt ttgggtttcc 1050

 acagtccctg cccccgcact cagaccccgc catggaaagc gagcaggcca 1100

 tgctctccga aagagaatac gagagaccca agcccagcaa cggggtcctg 1150

 aggcaccccc tggagccaga cagcagtgcc tcctgtttcc agcagctgag 1200

 agtgatcccg aaggtcacca agcacctgct ctcaaaccct gtgttcacct 1250

 gcatcatcct ggccgcctgc atggagattg cagtggtggc tggcttcgct 1300

 gcctttttgg ggaagtacct ggagcagcag tttaacctca ccacctcttc 1350

 tgccaaccag ctgcttggga tgactgcgat cccgtgtgct tgtctgggta 1400

 tcttcctggg aggtcttttg gtgaagaagc tcagcctgtc tgccctgggg 1450

 gccattcgga tggccatgct cgtcaacctg gtgtccactg cttgctacgt 1500

 ctccttcctc ttcctgggct gcgacactgg ccctgtggct ggggttactg 1550

 ttccctatgg aaacagcaca gcacctggct cagccctgga cccctactcg 1600

 ccctgcaata ataactgtga atgccaaacc gattccttca ctccagtgtg 1650

 tggggcagat ggcatcacct acctgtctgc ctgctttgct ggctgcaaca 1700

 gcacgaatct cacgggctgt gcgtgcctca ccaccgtccc tgctgagaac 1750

 gcaaccgtgg ttcctggaaa atgccccagt cctgggtgcc aagaggcctt 1800

 cctcactttc ctctgtgtga tgtgtatctg cagcctgatc ggtgccatgg 1850

 cacagacacc ctcagtcatc atcctcatca ggacagtcag ccctgaactc 1900

 aagtcttacg ctttgggagt tctttttctc ctccttcgtt tgttgggctt 1950

 catccctcca cccctcatct tcggggctgg catcgactcc acctgcctgt 2000

 tctggagcac gttctgtggg gagcaaggcg cctgcgtcct ctacgacaat 2050

 gtggtctacc gatacctgta tgtcagcatc gccatcgcgc tcaaatcctt 2100

 cgccttcatc ctgtacacca ccacgtggca gtgcctgagg aaaaactata 2150

 aacgctacat caaaaaccac gagggcgggc tgagcaccag tgagttcttt 2200

 gcctctactc tgaccctaga caacctgggg agggaccctg tgcccgcaaa 2250

 ccagacacat aggacaaagt ttatctataa cctggaagac catgagtggt 2300

 gtgaaaacat ggagtccgtt ttatagtgac taaaggaggg ctgaactctg 2350

 tattagtaat ccaagggtca tttttttctt aaaaaaagaa aaaaaggttc 2400

 caaaaaaaac caaaactcag tacacacaca caggcacaga tgcacacaca 2450

 cgcagacaga cacaccgact ttgtcctttt tctcagcatc agagccagac 2500

 aggattcaga ataaggagag aatgacatcg tgcggcaggg tcctggaggc 2550

 cactcgcgcg gctgggccac agagtctact ttgaaggcac ctcatggttt 2600

 tcaggatgct gacagctgca agcaacaggc actgccaaat tcagggaaca 2650

 gtggtggcca gcttggagga tggacatttc tggatacaca tacacataca 2700

 aaacagaaaa cattttttaa aagaagtttc ctaaaataaa 2740

<210> 5776
<211> 710
<212> PRT
<213> Homo sapien

<400> 5776
 Met Gln Gly Lys Lys Pro Gly Gly Ser Ser Gly Gly Gly Arg Ser
   1               5                  10                  15

 Gly Glu Leu Gln Gly Asp Glu Ala Gln Arg Asn Lys Lys Lys Lys
                  20                  25                  30

 Lys Lys Val Ser Cys Phe Ser Asn Ile Lys Ile Phe Leu Val Ser
                  35                  40                  45

 Glu Cys Ala Leu Met Leu Ala Gln Gly Thr Val Gly Ala Tyr Leu
                  50                  55                  60

 Val Ser Val Leu Thr Thr Leu Glu Arg Arg Phe Asn Leu Gln Ser
                  65                  70                  75

 Ala Asp Val Gly Val Ile Ala Ser Ser Phe Glu Ile Gly Asn Leu
                  80                  85                  90

 Ala Leu Ile Leu Phe Val Ser Tyr Phe Gly Ala Arg Gly His Arg
                  95                 100                 105

 Pro Arg Leu Ile Gly Cys Gly Gly Ile Val Met Ala Leu Gly Ala
                 110                 115                 120

 Leu Leu Ser Ala Leu Pro Glu Phe Leu Thr His Gln Tyr Lys Tyr
                 125                 130                 135

 Glu Ala Gly Glu Ile Arg Trp Gly Ala Glu Gly Arg Asp Val Cys
                 140                 145                 150

 Ala Ala Asn Gly Ser Gly Gly Asp Glu Gly Pro Asp Pro Asp Leu
                 155                 160                 165

 Ile Cys Arg Asn Arg Thr Ala Thr Asn Met Met Tyr Leu Leu Leu
                 170                 175                 180

 Ile Gly Ala Gln Val Leu Leu Gly Ile Gly Ala Thr Pro Val Gln
                 185                 190                 195

 Pro Leu Gly Val Ser Tyr Tyr Asp Asp His Val Arg Arg Lys Asp
                 200                 205                 210

 Ser Ser Leu Tyr Ile Gly Ile Leu Phe Thr Met Leu Val Phe Gly
                 215                 220                 225

 Pro Ala Cys Gly Phe Ile Leu Gly Ser Phe Cys Thr Lys Ile Tyr
                 230                 235                 240

 Val Asp Ala Val Phe Ile Asp Thr Ser Asn Leu Asp Ile Thr Pro
                 245                 250                 255

 Asp Asp Pro Arg Trp Ile Gly Ala Trp Trp Gly Gly Phe Leu Leu
                 260                 265                 270

 Cys Gly Ala Leu Leu Phe Phe Ser Ser Leu Leu Met Phe Gly Phe
                 275                 280                 285

 Pro Gln Ser Leu Pro Pro His Ser Asp Pro Ala Met Glu Ser Glu
                 290                 295                 300

 Gln Ala Met Leu Ser Glu Arg Glu Tyr Glu Arg Pro Lys Pro Ser
                 305                 310                 315

 Asn Gly Val Leu Arg His Pro Leu Glu Pro Asp Ser Ser Ala Ser
                 320                 325                 330

 Cys Phe Gln Gln Leu Arg Val Ile Pro Lys Val Thr Lys His Leu
                 335                 340                 345

 Leu Ser Asn Pro Val Phe Thr Cys Ile Ile Leu Ala Ala Cys Met
                 350                 355                 360

 Glu Ile Ala Val Val Ala Gly Phe Ala Ala Phe Leu Gly Lys Tyr
                 365                 370                 375

 Leu Glu Gln Gln Phe Asn Leu Thr Thr Ser Ser Ala Asn Gln Leu
                 380                 385                 390

 Leu Gly Met Thr Ala Ile Pro Cys Ala Cys Leu Gly Ile Phe Leu
                 395                 400                 405

 Gly Gly Leu Leu Val Lys Lys Leu Ser Leu Ser Ala Leu Gly Ala
                 410                 415                 420

 Ile Arg Met Ala Met Leu Val Asn Leu Val Ser Thr Ala Cys Tyr
                 425                 430                 435

 Val Ser Phe Leu Phe Leu Gly Cys Asp Thr Gly Pro Val Ala Gly
                 440                 445                 450

 Val Thr Val Pro Tyr Gly Asn Ser Thr Ala Pro Gly Ser Ala Leu
                 455                 460                 465

 Asp Pro Tyr Ser Pro Cys Asn Asn Asn Cys Glu Cys Gln Thr Asp
                 470                 475                 480

 Ser Phe Thr Pro Val Cys Gly Ala Asp Gly Ile Thr Tyr Leu Ser
                 485                 490                 495

 Ala Cys Phe Ala Gly Cys Asn Ser Thr Asn Leu Thr Gly Cys Ala
                 500                 505                 510

 Cys Leu Thr Thr Val Pro Ala Glu Asn Ala Thr Val Val Pro Gly
                 515                 520                 525

 Lys Cys Pro Ser Pro Gly Cys Gln Glu Ala Phe Leu Thr Phe Leu
                 530                 535                 540

 Cys Val Met Cys Ile Cys Ser Leu Ile Gly Ala Met Ala Gln Thr
                 545                 550                 555

 Pro Ser Val Ile Ile Leu Ile Arg Thr Val Ser Pro Glu Leu Lys
                 560                 565                 570

 Ser Tyr Ala Leu Gly Val Leu Phe Leu Leu Leu Arg Leu Leu Gly
                 575                 580                 585

 Phe Ile Pro Pro Pro Leu Ile Phe Gly Ala Gly Ile Asp Ser Thr
                 590                 595                 600

 Cys Leu Phe Trp Ser Thr Phe Cys Gly Glu Gln Gly Ala Cys Val
                 605                 610                 615

 Leu Tyr Asp Asn Val Val Tyr Arg Tyr Leu Tyr Val Ser Ile Ala
                 620                 625                 630

 Ile Ala Leu Lys Ser Phe Ala Phe Ile Leu Tyr Thr Thr Thr Trp
                 635                 640                 645

 Gln Cys Leu Arg Lys Asn Tyr Lys Arg Tyr Ile Lys Asn His Glu
                 650                 655                 660

 Gly Gly Leu Ser Thr Ser Glu Phe Phe Ala Ser Thr Leu Thr Leu
                 665                 670                 675

 Asp Asn Leu Gly Arg Asp Pro Val Pro Ala Asn Gln Thr His Arg
                 680                 685                 690

 Thr Lys Phe Ile Tyr Asn Leu Glu Asp His Glu Trp Cys Glu Asn
                 695                 700                 705

 Met Glu Ser Val Leu
                 710

<210> 5777
<211> 2331
<212> DNA
<213> Homo sapien

<400> 5777
 cttcgcggct tggtaacata aaagtttgtt tcaccacgta agccggacct 50

 cgcactccgg tcccggtctc gtcgccaaga tggtgaagcc caagtacaaa 100

 ggacggagca ccatcaaccc gtccaaggcc agcacaaacc cagatcgagt 150

 gcagggagca ggaggccaaa acatgaggga ccgggccacc atccggcgcc 200

 tgaatatgta taggcaaaag gagcgcagga acagtcgtgg taaaataatt 250

 aaacccctgc aatatcaatc aacggtggct tctggcacag tggcaagagt 300

 agagccaaat attaaatggt ttggaaacac acgtgtgatt aagcagtcat 350

 cattacaaaa atttcaagag gaaatggata cagttatgaa ggatccatac 400

 aaagttgtca tgaagcaaag caagttacca atgtctcttc tccatgatcg 450

 aatccggcct cataacttga aggtgcacat tcttgatact gaaagttttg 500

 aaactacatt tggccctaag tcacagagga aacgaccaaa cttatttgca 550

 agtgatatgc agtctcttat cgaaaatgct gaaatgtcca ctgagagcta 600

 tgaccagggc aaggatcgtg atttggtaac tgaagacact ggtgtgagaa 650

 atgaagctca agaagagatc tataaaaagg gacagtccaa aagaatatgg 700

 ggtgagctct acaaggtgat agattcatca gatgttgtag ttcaagttct 750

 tgatgctaga gatccaatgg gtactcgttc ccctcacatt gaaacttacc 800

 tgaagaagga aaaaccttgg aaacacctca tttttgtact taacaaatgt 850

 gaccttgttc caacctgggc aacaaaacgg tgggttgctg tcctctccca 900

 ggattatcca acacttgctt tccatgcaag ccttactaac ccgtttggca 950

 agggagcatt cattcagctt ctgcggcagt ttggaaagtt gcacactgac 1000

 aagaaacaga tcagtgttgg gttcattggc tatccaaatg ttggcaagag 1050

 ctctgtgata aatacattgc gttctaagaa agtttgcaac gtggctccca 1100

 ttgcaggtga aacaaaggtc tggcagtata ttactttgat gcgtcggata 1150

 ttcctgattg actgtccagg tgtggtttac ccctctgagg actccgagac 1200

 agacattgtg ctaaaaggag ttgttcaagt agaaaaaatt aagagtcctg 1250

 aagaccacat tggtgctgta cttgaacgag caaagccaga atatatcagc 1300

 aaaacataca agattgattc ttgggagaat gctgaggact ttcttgagaa 1350

 gctcgctttc cggactggga agttactaaa gggtggagag cccgacttgc 1400

 agactgtggg taagatggtc ctcaatgact ggcagagggg ccggattcct 1450

 ttctttgtca agccacccaa tgcagagcca cttgtggccc cccagcttct 1500

 accctcctca tctttggaag ttgtcccaga agcagcccag aacaatccag 1550

 gggaggaagt cacagaaact gcaggtgaag ggtcagaatc catcattaag 1600

 gaagaaacag aagagaacag tcactgtgat gctaacacag agatgcagca 1650

 gattctcaca cgagttcggc agaactttgg taaaatcaac gtggtgcctc 1700

 agttttctgg ggatgacctg gttcctgtgg aggtgtcaga tcttgaggaa 1750

 gagcttgaga gcttttctga tgaagaggag gaggaacagg agcaacaaag 1800

 agatgatgcg gaagagtctt cctcggagcc tgaggaggaa aatgtgggaa 1850

 acgacaccaa agccgttatt aaagcactgg atgagaagat tgccaaatat 1900

 cagaagtttc tagacaaagc caaagccaaa aagttttcag cagtcagaat 1950

 atccaaggga ctgagtgaaa agatatttgc aaaacctgaa gaacaaagaa 2000

 aaacactgga agaagatgta gatgacagag caccttccaa aaagggaaag 2050

 aagcggaagg cacaaaggga agaggaacag gaacattcaa ataaagctcc 2100

 cagggcgctt acatcaaaag aacggaggcg agcagtacga cagcaacggc 2150

 cgaaaaaagt tggtgtgcgc tactatgaaa cacacaacgt gaaaaatagg 2200

 aacaggaaca aaaagaagac caatgactca gagggacaga aacacaaacg 2250

 caaaaaattc agacaaaagc agtaatgttt aaaaggtttt tattaaatta 2300

 tacaaaaaca ggcaaaaaaa aaaaaaaaaa a 2331

<210> 5778
<211> 731
<212> PRT
<213> Homo sapien

<400> 5778
 Met Val Lys Pro Lys Tyr Lys Gly Arg Ser Thr Ile Asn Pro Ser
   1               5                  10                  15

 Lys Ala Ser Thr Asn Pro Asp Arg Val Gln Gly Ala Gly Gly Gln
                  20                  25                  30

 Asn Met Arg Asp Arg Ala Thr Ile Arg Arg Leu Asn Met Tyr Arg
                  35                  40                  45

 Gln Lys Glu Arg Arg Asn Ser Arg Gly Lys Ile Ile Lys Pro Leu
                  50                  55                  60

 Gln Tyr Gln Ser Thr Val Ala Ser Gly Thr Val Ala Arg Val Glu
                  65                  70                  75

 Pro Asn Ile Lys Trp Phe Gly Asn Thr Arg Val Ile Lys Gln Ser
                  80                  85                  90

 Ser Leu Gln Lys Phe Gln Glu Glu Met Asp Thr Val Met Lys Asp
                  95                 100                 105

 Pro Tyr Lys Val Val Met Lys Gln Ser Lys Leu Pro Met Ser Leu
                 110                 115                 120

 Leu His Asp Arg Ile Arg Pro His Asn Leu Lys Val His Ile Leu
                 125                 130                 135

 Asp Thr Glu Ser Phe Glu Thr Thr Phe Gly Pro Lys Ser Gln Arg
                 140                 145                 150

 Lys Arg Pro Asn Leu Phe Ala Ser Asp Met Gln Ser Leu Ile Glu
                 155                 160                 165

 Asn Ala Glu Met Ser Thr Glu Ser Tyr Asp Gln Gly Lys Asp Arg
                 170                 175                 180

 Asp Leu Val Thr Glu Asp Thr Gly Val Arg Asn Glu Ala Gln Glu
                 185                 190                 195

 Glu Ile Tyr Lys Lys Gly Gln Ser Lys Arg Ile Trp Gly Glu Leu
                 200                 205                 210

 Tyr Lys Val Ile Asp Ser Ser Asp Val Val Val Gln Val Leu Asp
                 215                 220                 225

 Ala Arg Asp Pro Met Gly Thr Arg Ser Pro His Ile Glu Thr Tyr
                 230                 235                 240

 Leu Lys Lys Glu Lys Pro Trp Lys His Leu Ile Phe Val Leu Asn
                 245                 250                 255

 Lys Cys Asp Leu Val Pro Thr Trp Ala Thr Lys Arg Trp Val Ala
                 260                 265                 270

 Val Leu Ser Gln Asp Tyr Pro Thr Leu Ala Phe His Ala Ser Leu
                 275                 280                 285

 Thr Asn Pro Phe Gly Lys Gly Ala Phe Ile Gln Leu Leu Arg Gln
                 290                 295                 300

 Phe Gly Lys Leu His Thr Asp Lys Lys Gln Ile Ser Val Gly Phe
                 305                 310                 315

 Ile Gly Tyr Pro Asn Val Gly Lys Ser Ser Val Ile Asn Thr Leu
                 320                 325                 330

 Arg Ser Lys Lys Val Cys Asn Val Ala Pro Ile Ala Gly Glu Thr
                 335                 340                 345

 Lys Val Trp Gln Tyr Ile Thr Leu Met Arg Arg Ile Phe Leu Ile
                 350                 355                 360

 Asp Cys Pro Gly Val Val Tyr Pro Ser Glu Asp Ser Glu Thr Asp
                 365                 370                 375

 Ile Val Leu Lys Gly Val Val Gln Val Glu Lys Ile Lys Ser Pro
                 380                 385                 390

 Glu Asp His Ile Gly Ala Val Leu Glu Arg Ala Lys Pro Glu Tyr
                 395                 400                 405

 Ile Ser Lys Thr Tyr Lys Ile Asp Ser Trp Glu Asn Ala Glu Asp
                 410                 415                 420

 Phe Leu Glu Lys Leu Ala Phe Arg Thr Gly Lys Leu Leu Lys Gly
                 425                 430                 435

 Gly Glu Pro Asp Leu Gln Thr Val Gly Lys Met Val Leu Asn Asp
                 440                 445                 450

 Trp Gln Arg Gly Arg Ile Pro Phe Phe Val Lys Pro Pro Asn Ala
                 455                 460                 465

 Glu Pro Leu Val Ala Pro Gln Leu Leu Pro Ser Ser Ser Leu Glu
                 470                 475                 480

 Val Val Pro Glu Ala Ala Gln Asn Asn Pro Gly Glu Glu Val Thr
                 485                 490                 495

 Glu Thr Ala Gly Glu Gly Ser Glu Ser Ile Ile Lys Glu Glu Thr
                 500                 505                 510

 Glu Glu Asn Ser His Cys Asp Ala Asn Thr Glu Met Gln Gln Ile
                 515                 520                 525

 Leu Thr Arg Val Arg Gln Asn Phe Gly Lys Ile Asn Val Val Pro
                 530                 535                 540

 Gln Phe Ser Gly Asp Asp Leu Val Pro Val Glu Val Ser Asp Leu
                 545                 550                 555

 Glu Glu Glu Leu Glu Ser Phe Ser Asp Glu Glu Glu Glu Glu Gln
                 560                 565                 570

 Glu Gln Gln Arg Asp Asp Ala Glu Glu Ser Ser Ser Glu Pro Glu
                 575                 580                 585

 Glu Glu Asn Val Gly Asn Asp Thr Lys Ala Val Ile Lys Ala Leu
                 590                 595                 600

 Asp Glu Lys Ile Ala Lys Tyr Gln Lys Phe Leu Asp Lys Ala Lys
                 605                 610                 615

 Ala Lys Lys Phe Ser Ala Val Arg Ile Ser Lys Gly Leu Ser Glu
                 620                 625                 630

 Lys Ile Phe Ala Lys Pro Glu Glu Gln Arg Lys Thr Leu Glu Glu
                 635                 640                 645

 Asp Val Asp Asp Arg Ala Pro Ser Lys Lys Gly Lys Lys Arg Lys
                 650                 655                 660

 Ala Gln Arg Glu Glu Glu Gln Glu His Ser Asn Lys Ala Pro Arg
                 665                 670                 675

 Ala Leu Thr Ser Lys Glu Arg Arg Arg Ala Val Arg Gln Gln Arg
                 680                 685                 690

 Pro Lys Lys Val Gly Val Arg Tyr Tyr Glu Thr His Asn Val Lys
                 695                 700                 705

 Asn Arg Asn Arg Asn Lys Lys Lys Thr Asn Asp Ser Glu Gly Gln
                 710                 715                 720

 Lys His Lys Arg Lys Lys Phe Arg Gln Lys Gln
                 725                 730

<210> 5779
<211> 1272
<212> DNA
<213> Homo sapien

<400> 5779
 gaattcggcc aaagaggcct atgcttctct gaagacttgc agcaaggctt 50

 gctgaggctc acagaagata gccccagtgt tttggagtgg ttttgaatgt 100

 gattctgaga tcagactgac tgagctggaa tcctggcttt atatcttacc 150

 agctacacaa ccttggagtc ttagaaattt tttcttttca ataagcagtc 200

 atccttactt tccctcaaga tgacaaacag ttcgttcttc tgcccagttt 250

 ataaagatct ggagccattc acgtattttt tttatttagt tttccttgtt 300

 ggaattattg gaagttgttt tgcaacctgg gcttttatac agaagaatac 350

 gaatcacagg tgtgtgagca tctacttaat taatttgctt acagccgatt 400

 tcctgcttac tctggcatta ccagtgaaaa ttgttgttga cttgggtgtg 450

 gcaccttgga agctgaagat attccactgc caagtaacag cctgcctcat 500

 ctatatcaat atgtatttat caattatctt cttagcattt gtcagcattg 550

 accgctgtct tcagctgaca cacagctgca agatctaccg aatacaagaa 600

 cccggatttg ccaaaatgat atcaaccgtt gtgtggctaa tggtccttct 650

 tataatggtg ccaaatatga tgattcccat caaagacatc aaggaaaagt 700

 caaatgtggg ttgtatggag tttaaaaagg aatttggaag aaattggcat 750

 ttgctgacaa atttcatatg tgtagcaata tttttaaatt tctcagccat 800

 cattttaata tccaattgcc ttgtaattcg acagctctac agaaacaaag 850

 ataatgaaaa ttacccaaat gtgaaaaagg ctctcatcaa catactttta 900

 gtgaccacgg gctacatcat atgctttgtt ccttaccaca ttgtccgaat 950

 cccgtatacc ctcagccaga cagaagtcat aactgattgc tcaaccagga 1000

 tttcactctt caaagccaaa gaggctacac tgctcctggc tgtgtcgaac 1050

 ctgtgctttg atcctatcct gtactatcac ctctcaaaag cattccgctc 1100

 aaaggtcact gagacttttg cctcacctaa agagaccaag gctcagaaag 1150

 aaaaattaag atgtgaaaat aatgcataaa agacaggatt ttttgtgcta 1200

 ccaattctgg ccttactgga ccataaagtt aattatagct ttgaaagata 1250

 aaaaaaaaaa aaaagcggcc gc 1272

<210> 5780
<211> 319
<212> PRT
<213> Homo sapien

<400> 5780
 Met Thr Asn Ser Ser Phe Phe Cys Pro Val Tyr Lys Asp Leu Glu
   1               5                  10                  15

 Pro Phe Thr Tyr Phe Phe Tyr Leu Val Phe Leu Val Gly Ile Ile
                  20                  25                  30

 Gly Ser Cys Phe Ala Thr Trp Ala Phe Ile Gln Lys Asn Thr Asn
                  35                  40                  45

 His Arg Cys Val Ser Ile Tyr Leu Ile Asn Leu Leu Thr Ala Asp
                  50                  55                  60

 Phe Leu Leu Thr Leu Ala Leu Pro Val Lys Ile Val Val Asp Leu
                  65                  70                  75

 Gly Val Ala Pro Trp Lys Leu Lys Ile Phe His Cys Gln Val Thr
                  80                  85                  90

 Ala Cys Leu Ile Tyr Ile Asn Met Tyr Leu Ser Ile Ile Phe Leu
                  95                 100                 105

 Ala Phe Val Ser Ile Asp Arg Cys Leu Gln Leu Thr His Ser Cys
                 110                 115                 120

 Lys Ile Tyr Arg Ile Gln Glu Pro Gly Phe Ala Lys Met Ile Ser
                 125                 130                 135

 Thr Val Val Trp Leu Met Val Leu Leu Ile Met Val Pro Asn Met
                 140                 145                 150

 Met Ile Pro Ile Lys Asp Ile Lys Glu Lys Ser Asn Val Gly Cys
                 155                 160                 165

 Met Glu Phe Lys Lys Glu Phe Gly Arg Asn Trp His Leu Leu Thr
                 170                 175                 180

 Asn Phe Ile Cys Val Ala Ile Phe Leu Asn Phe Ser Ala Ile Ile
                 185                 190                 195

 Leu Ile Ser Asn Cys Leu Val Ile Arg Gln Leu Tyr Arg Asn Lys
                 200                 205                 210

 Asp Asn Glu Asn Tyr Pro Asn Val Lys Lys Ala Leu Ile Asn Ile
                 215                 220                 225

 Leu Leu Val Thr Thr Gly Tyr Ile Ile Cys Phe Val Pro Tyr His
                 230                 235                 240

 Ile Val Arg Ile Pro Tyr Thr Leu Ser Gln Thr Glu Val Ile Thr
                 245                 250                 255

 Asp Cys Ser Thr Arg Ile Ser Leu Phe Lys Ala Lys Glu Ala Thr
                 260                 265                 270

 Leu Leu Leu Ala Val Ser Asn Leu Cys Phe Asp Pro Ile Leu Tyr
                 275                 280                 285

 Tyr His Leu Ser Lys Ala Phe Arg Ser Lys Val Thr Glu Thr Phe
                 290                 295                 300

 Ala Ser Pro Lys Glu Thr Lys Ala Gln Lys Glu Lys Leu Arg Cys
                 305                 310                 315

 Glu Asn Asn Ala


<210> 5781
<211> 2168
<212> DNA
<213> Homo sapien

<400> 5781
 tccctgtcct gcgcccgcgc gccccgggag cctacccagc acgcgctccg 50

 cgcccactgg ttccctccag ccgccgccgt ccagccgagt ccccactccg 100

 gagtcgccgc tgccgcgggg acatggtcct ctgcgttcag gggtgagcac 150

 ccccttgtaa gctcagggct actgttgggt gtcagggaac aaagttttag 200

 actgctgcgc tccaaagcgg gcacacacat gtacctagaa cacaccagcc 250

 actgtcccca ccatgatgat gacacagcca tggacacacc cctgcccaga 300

 cctcgtcctt tgctggctgt ggagcggact gggcagcggc ccctgtgggc 350

 cccgtccctg gaactgccca agccagtcat gcagcccttg cctgctgggg 400

 ccttcctcga ggaggtggca gagggtaccc cagcccagac agagagtgag 450

 ccaaaggtgc tggacccaga ggaggatctg ctgtgcatag ccaagacctt 500

 ctcctacctt cgggaatctg gctggtattg gggttccatt acggccagcg 550

 aggcccgaca acacctgcag aagatgccag aaggcacgtt cttagtacgt 600

 gacagcacgc accccagcta cctgttcacg ctgtcagtga aaaccactcg 650

 tggccccacc aatgtacgca ttgagtatgc cgactccagc ttccgtctgg 700

 actccaactg cttgtccagg ccacgcatcc tggcctttcc ggatgtggtc 750

 agccttgtgc agcactatgt ggcctcctgc actgctgata cccgaagcga 800

 cagccccgat cctgctccca ccccggccct gcctatgcct aaggaggatg 850

 cgcctagtga cccagcactg cctgctcctc caccagccac tgctgtacac 900

 ctaaaactgg tgcagccctt tgtacgcaga agcagtgccc gcagcctgca 950

 acacctgtgc cgccttgtca tcaaccgtct ggtggccgac gtggactgcc 1000

 tgccactgcc ccggcgcatg gccgactacc tccgacagta ccccttccag 1050

 ctctgactgt acggggcaat ctgcccaccc tcacccagtc gcaccctgga 1100

 ggggacatca gccccagctg gacttgggcc cccactgtcc ctcctccagg 1150

 catcctggtg cctgcatacc tctggcagct ggcccaggaa gagccagcaa 1200

 gagcaaggca tgggagaggg gaggtgtcac acaacttgga ggtaaaatgc 1250

 ccccaggccg catgtggctt cattatactg agccatgtgt cagaggatgg 1300

 ggagacaggc aggaccttgt ctcacctgtg ggctgggccc aaacctccac 1350

 tcgcttgcct gccctggcca cctgaactgt atgggcactc tcagccctgg 1400

 tttttcaatc cccagggtcg gtaggacccc tactggcagc cagcctctgt 1450

 ttctgggagg atgacatgca gaggaactga gatcgacagt gactagtgac 1500

 cccttgttga ggggtaagcc aggctagggg actgcacaat tatacactat 1550

 ttatttattt attctccttg gggttggtgt caggggcaaa ccaaccccac 1600

 ctctatgccc tgagccctgg tagtccaaag accccaactc tgccctggct 1650

 tctctggttc ttccctgtgg aaagcccatc ctgagacatc ttgctggaac 1700

 caaggcaatc ctggatgtcc tggtactgac ccacccctct gtgaatgtgt 1750

 ccactctctt ctgcccccag ccatatttgg ggaggatgga caactacaat 1800

 aggtaagaaa atgcagccgg agcctcagtc cccagcagag cctgtgtctc 1850

 accccctcac aggacagagc tgtatctgca taaagctggt ctcactgtgg 1900

 cgcaggcccc ggggggagtg cctgtgctgt caggaaaagg gggtgctggt 1950

 ttgagggcca ccactgcagt tctgctaggt ctgcttcctg cccaggaagg 2000

 tgcctgcaca tgaaaggaga gaaatacacg tctgataaga cttcatgaaa 2050

 taataattat agcaaagaac agtttggtgg tcttttctct tccactgatt 2100

 tttctgtaat gaacattata cctttattac ctctttattt tattacctct 2150

 ataataaaat gatacctt 2168

<210> 5782
<211> 258
<212> PRT
<213> Homo sapien

<400> 5782
 Met Asp Thr Pro Leu Pro Arg Pro Arg Pro Leu Leu Ala Val Glu
   1               5                  10                  15

 Arg Thr Gly Gln Arg Pro Leu Trp Ala Pro Ser Leu Glu Leu Pro
                  20                  25                  30

 Lys Pro Val Met Gln Pro Leu Pro Ala Gly Ala Phe Leu Glu Glu
                  35                  40                  45

 Val Ala Glu Gly Thr Pro Ala Gln Thr Glu Ser Glu Pro Lys Val
                  50                  55                  60

 Leu Asp Pro Glu Glu Asp Leu Leu Cys Ile Ala Lys Thr Phe Ser
                  65                  70                  75

 Tyr Leu Arg Glu Ser Gly Trp Tyr Trp Gly Ser Ile Thr Ala Ser
                  80                  85                  90

 Glu Ala Arg Gln His Leu Gln Lys Met Pro Glu Gly Thr Phe Leu
                  95                 100                 105

 Val Arg Asp Ser Thr His Pro Ser Tyr Leu Phe Thr Leu Ser Val
                 110                 115                 120

 Lys Thr Thr Arg Gly Pro Thr Asn Val Arg Ile Glu Tyr Ala Asp
                 125                 130                 135

 Ser Ser Phe Arg Leu Asp Ser Asn Cys Leu Ser Arg Pro Arg Ile
                 140                 145                 150

 Leu Ala Phe Pro Asp Val Val Ser Leu Val Gln His Tyr Val Ala
                 155                 160                 165

 Ser Cys Thr Ala Asp Thr Arg Ser Asp Ser Pro Asp Pro Ala Pro
                 170                 175                 180

 Thr Pro Ala Leu Pro Met Pro Lys Glu Asp Ala Pro Ser Asp Pro
                 185                 190                 195

 Ala Leu Pro Ala Pro Pro Pro Ala Thr Ala Val His Leu Lys Leu
                 200                 205                 210

 Val Gln Pro Phe Val Arg Arg Ser Ser Ala Arg Ser Leu Gln His
                 215                 220                 225

 Leu Cys Arg Leu Val Ile Asn Arg Leu Val Ala Asp Val Asp Cys
                 230                 235                 240

 Leu Pro Leu Pro Arg Arg Met Ala Asp Tyr Leu Arg Gln Tyr Pro
                 245                 250                 255

 Phe Gln Leu


<210> 5783
<211> 1372
<212> DNA
<213> Homo sapien

<400> 5783
 gcacgagggc gcttttgtct ccggtgagtt ttgtggcggg aagcttctgc 50

 gctggtgctt agtaaccgac tttcctccgg actcctgcac gacctgctcc 100

 tacagccggc gatccactcc cggctgttcc cccggagggt ccagaggcct 150

 ttcagaagga gaaggcagct ctgtttctct gcagaggagt agggtccttt 200

 cagccatgaa gcatgtgttg aacctctacc tgttaggtgt ggtactgacc 250

 ctactctcca tcttcgttag agtgatggag tccctagaag gcttactaga 300

 gagcccatcg cctgggacct cctggaccac cagaagccaa ctagccaaca 350

 cagagcccac caagggcctt ccagaccatc catccagaag catgtgataa 400

 gacctccttc catactggcc atattttgga acactgacct agacatgtcc 450

 agatgggagt cccattccta gcagacaagc tgagcaccgt tgtaaccaga 500

 gaactattac taggccttga agaacctgtc taactggatg ctcattgcct 550

 gggcaaggcc tgtttaggcc ggttgcggtg gctcatgcct gtaatcctag 600

 cactttggga ggctgaggtg ggtggatcac ctgaggtcag gagttcgaga 650

 ccagcctcgc caacatggcg aaaccccatc tctactaaaa atacaaaagt 700

 tagctgggtg tggtggcaga ggcctgtaat cccagttcct tgggaggctg 750

 aggcgggaga attgcttgaa cccggggacg gaggttgcag tgaaccgaga 800

 tcgcactgct gtacccagcc tgggccacag tgcaagactc catctcaaaa 850

 aaaaaaagaa aagaaaaagc ctgtttaatg cacaggtgtg agtggattgc 900

 ttatggctat gagataggtt gatctcgccc ttaccccggg gtctggtgta 950

 tgctgtgctt tcctcagcag tatggctctg acatctctta gatgtcccaa 1000

 cttcagctgt tgggagatgg tgatattttc aaccctactt cctaaacatc 1050

 tgtctggggt tcctttagtc ttgaatgtct tatgctcaat tatttggtgt 1100

 tgagcctctc ttccacaaga gctcctccat gtttggatag cagttgaaga 1150

 ggttgtgtgg gtgggctgtt gggagtgagg atggagtgtt cagtgcccat 1200

 ttctcatttt acattttaaa gtcgttcctc caacatagtg tgtattggtc 1250

 tgaagggggt ggtgggatgc caaagcctgc tcaagttatg gacattgtgg 1300

 ccaccatgtg gcttaaatga ttttttctaa ctaataaagt ggaatatata 1350

 tttcaaaaaa aaaaaaaaaa aa 1372

<210> 5784
<211> 63
<212> PRT
<213> Homo sapien

<400> 5784
 Met Lys His Val Leu Asn Leu Tyr Leu Leu Gly Val Val Leu Thr
   1               5                  10                  15

 Leu Leu Ser Ile Phe Val Arg Val Met Glu Ser Leu Glu Gly Leu
                  20                  25                  30

 Leu Glu Ser Pro Ser Pro Gly Thr Ser Trp Thr Thr Arg Ser Gln
                  35                  40                  45

 Leu Ala Asn Thr Glu Pro Thr Lys Gly Leu Pro Asp His Pro Ser
                  50                  55                  60

 Arg Ser Met


<210> 5785
<211> 1301
<212> DNA
<213> Homo sapien

<400> 5785
 agactctcca cctgctccct gggaccatcg cccaccatgg ctgtggccca 50

 gcagctgcgg gccgagagtg actttgaaca gcttccggat gatgttgcca 100

 tctcggccaa cattgctgac atcgaggaga agagaggctt caccagccac 150

 tttgttttcg tcatcgaggt gaagacaaaa ggaggatcca agtacctcat 200

 ctaccgccgc taccgccagt tccatgcttt gcagagcaag ctggaggagc 250

 gcttcgggcc agacagcaag agcagtgccc tggcctgtac cctgcccaca 300

 ctcccagcca aagtctacgt gggtgtgaaa caggagatcg ccgagatgcg 350

 gatacctgcc ctcaacgcct acatgaagag cctgctcagc ctgccggtct 400

 gggtgctgat ggatgaggac gtccggatct tcttttacca gtcgccctat 450

 gactcagagc aggtgcccca ggcactccgc cggctccgcc cgcgcacccg 500

 gaaagtcaag agcgtgtccc cacagggcaa cagcgttgac cgcatggcag 550

 ctccgagagc agaggctcta tttgacttca ctggaaacag caaactggag 600

 ctgaatttca aagctggaga tgtgatcttc ctcctcagtc ggatcaacaa 650

 agactggctg gagggcactg tccggggagc cacgggcatc ttccctctct 700

 ccttcgtgaa gatcctcaaa gacttccctg aggaggacga ccccaccaac 750

 tggctgcgtt gctactacta cgaagacacc atcagcacca tcaagtctgt 800

 ggcctgggag ggaggggcct gtccagcctt cctgccatcc ctacgaccac 850

 cgcccctcac atcaccttct catgggtccc tctcccactc caaagccccc 900

 agtggctccc agatgagcca caatgctgta acaagccatc aacgtccagg 950

 gtggcctggc cagcctcatt cccctttccc ccaccccaca ccccacttcc 1000

 agcctgatgc ctccttactc cagcctgtca cccccttagg gacatcgcgg 1050

 tggaggaaga tctcagcagc actcccctat tgaaagacct gctggagctc 1100

 acaaggcggg agttccagag agaggacata gctctgaatt accgggacgc 1150

 tgagggggat ctggttcggc tgctgtcgga tgaggacgta gcgctcatgg 1200

 tgcggcaggc tcgtggcctc ccctcccaga agcgcctctt cccctggaag 1250

 ctgcacatca cgcagaagga caactacagg gtctacaaca cgatgccatg 1300

 a 1301

<210> 5786
<211> 348
<212> PRT
<213> Homo sapien

<400> 5786
 Met Ala Val Ala Gln Gln Leu Arg Ala Glu Ser Asp Phe Glu Gln
   1               5                  10                  15

 Leu Pro Asp Asp Val Ala Ile Ser Ala Asn Ile Ala Asp Ile Glu
                  20                  25                  30

 Glu Lys Arg Gly Phe Thr Ser His Phe Val Phe Val Ile Glu Val
                  35                  40                  45

 Lys Thr Lys Gly Gly Ser Lys Tyr Leu Ile Tyr Arg Arg Tyr Arg
                  50                  55                  60

 Gln Phe His Ala Leu Gln Ser Lys Leu Glu Glu Arg Phe Gly Pro
                  65                  70                  75

 Asp Ser Lys Ser Ser Ala Leu Ala Cys Thr Leu Pro Thr Leu Pro
                  80                  85                  90

 Ala Lys Val Tyr Val Gly Val Lys Gln Glu Ile Ala Glu Met Arg
                  95                 100                 105

 Ile Pro Ala Leu Asn Ala Tyr Met Lys Ser Leu Leu Ser Leu Pro
                 110                 115                 120

 Val Trp Val Leu Met Asp Glu Asp Val Arg Ile Phe Phe Tyr Gln
                 125                 130                 135

 Ser Pro Tyr Asp Ser Glu Gln Val Pro Gln Ala Leu Arg Arg Leu
                 140                 145                 150

 Arg Pro Arg Thr Arg Lys Val Lys Ser Val Ser Pro Gln Gly Asn
                 155                 160                 165

 Ser Val Asp Arg Met Ala Ala Pro Arg Ala Glu Ala Leu Phe Asp
                 170                 175                 180

 Phe Thr Gly Asn Ser Lys Leu Glu Leu Asn Phe Lys Ala Gly Asp
                 185                 190                 195

 Val Ile Phe Leu Leu Ser Arg Ile Asn Lys Asp Trp Leu Glu Gly
                 200                 205                 210

 Thr Val Arg Gly Ala Thr Gly Ile Phe Pro Leu Ser Phe Val Lys
                 215                 220                 225

 Ile Leu Lys Asp Phe Pro Glu Glu Asp Asp Pro Thr Asn Trp Leu
                 230                 235                 240

 Arg Cys Tyr Tyr Tyr Glu Asp Thr Ile Ser Thr Ile Lys Ser Val
                 245                 250                 255

 Ala Trp Glu Gly Gly Ala Cys Pro Ala Phe Leu Pro Ser Leu Arg
                 260                 265                 270

 Pro Pro Pro Leu Thr Ser Pro Ser His Gly Ser Leu Ser His Ser
                 275                 280                 285

 Lys Ala Pro Ser Gly Ser Gln Met Ser His Asn Ala Val Thr Ser
                 290                 295                 300

 His Gln Arg Pro Gly Trp Pro Gly Gln Pro His Ser Pro Phe Pro
                 305                 310                 315

 His Pro Thr Pro His Phe Gln Pro Asp Ala Ser Leu Leu Gln Pro
                 320                 325                 330

 Val Thr Pro Leu Gly Thr Ser Arg Trp Arg Lys Ile Ser Ala Ala
                 335                 340                 345

 Leu Pro Tyr


<210> 5787
<211> 2189
<212> DNA
<213> Homo sapien

<400> 5787
 agcggggcgg aagtcggttc ccgtgacgcg gcgcgcccca agggccggct 50

 ccgttgaggg aagggagccc gcccggtggc ggctggggtc ggctgctggg 100

 aggaggtggt gggctggttc ggacgtgggt cgaggctgta gcaggactcc 150

 aggtgaggcc tgaggaccac tctgccctcc cgcggcccgg gctcgcgccg 200

 ggggccattt aatcccgaca gcttgcggcc tgacgtcgct gcggcctggc 250

 agtgaccacg tcggcgtccg gcccctcggc cggcgataga gttgcggcta 300

 aaatgaaagg acgcccagtt acatttgcat cgtagataaa gaaagagcat 350

 ttagtataag catgtccgaa atgttgcgtg ggatgtaggc atactaaaac 400

 cttattcgtg gcctgtctga aatccaaatg gagctgggta ttctgtgttt 450

 ttatttgcta aatctggcag ccgtacccgc ggccccgggc agggagggag 500

 cagctgggct cggccagacc ctgccggcgt ctggggggcc tgcgaagtgg 550

 aggggagacg ggcagccggg cagtggccgg cgttccccgg agctcggacc 600

 ggttggattg gactccgacg ctaccgctcc ctctgctgaa ctattccgga 650

 tgtaaaacac tagggatcgg agtttttctt ggttttttaa tctcattcta 700

 gtgaccgaga agcttgctgg cagtgcgctg atggatctgt gtgaataggc 750

 catttatttg acctcttcag taacactgtt ctaaccggct gaaactgctt 800

 tcttaggcat tttcttaaaa gcttggtggt taagagcacg gaatttcgag 850

 tcagatttcc aatcttggct ctatcactat cctcggagtc atggggcagt 900

 cacatcatcc ctgtctctgt aatggtagct gcccctggat aagtgttatt 950

 aggtgattca gaagggtggg ctgttgccct tgcctgaggt tgcagtctgc 1000

 ggttcccaag ccccaagacc cgcctcagaa ctaactgcat ttgcttttga 1050

 ctcctggcct ttctctaggg ttgggaagaa catggaaagt gacctccctg 1100

 ccaaataact cagaagagga gtgtcggtag ccaaatgttt cttcagaata 1150

 cgtgtaaaag aaatgttttt cttccatcta ggaagatgtt accgagtact 1200

 tcagtgaatt ccttagtgca ggggaacgga gtcttgaatt ccagggatgc 1250

 ggcaagacac acagccggag cgaaacgcta caaatatctg agaaggcttt 1300

 tccgctttcg gcaaatggac tttgaatttg ctgcctggca gatgctctac 1350

 ctgttcacat ccccacagag agtttacaga aattttcatt atcgaaaaca 1400

 gacgaaggac cagtgggcca gagatgaccc tgctttcttg gtcctgttaa 1450

 gtatctggct ctgtgtgtcc actataggat ttggctttgt gctggacatg 1500

 ggattctttg agacaataaa gcttctcctt tgggttgtac tcatagattg 1550

 tgtaggcgtt ggtcttctga tagcaacttt aatgtggttc atctctaaca 1600

 agtatttagt gaaacgacag agcagagact atgatgtgga atggggctat 1650

 gcttttgatg tgcatctcaa tgctttttat ccactcctgg tcattttgca 1700

 ttttatccag ctttttttca tcaaccatgt tatcctgaca gacacattta 1750

 ttggatattt agttggaaat accttatggt tggttgcagt tggctattat 1800

 atctatgtaa ctttcctggg atacagtgca ttgccatttt tgaaaaatac 1850

 agtaattctt ctgtatccat ttgcacctct gattctgctc tacgggcttt 1900

 ccctggcact gggatggaac ttcacccata ctctctgttc tttctataag 1950

 tacagagtga aataaaaagt gagaagaaga ttcaatcgta actgtgtcaa 2000

 cagtattgtg aagtgatcat ttcttgtaaa acttgtaaat aaactatcat 2050

 ctttgtagat atcttaaagg tgtaaagttt gcaaatttga agaaatatat 2100

 attaacactg tggtcaggta cattccttaa aactaattaa atgtacattt 2150

 ctataataaa tattttttaa actaaaaaaa aaaaaaaaa 2189

<210> 5788
<211> 259
<212> PRT
<213> Homo sapien

<400> 5788
 Met Leu Pro Ser Thr Ser Val Asn Ser Leu Val Gln Gly Asn Gly
   1               5                  10                  15

 Val Leu Asn Ser Arg Asp Ala Ala Arg His Thr Ala Gly Ala Lys
                  20                  25                  30

 Arg Tyr Lys Tyr Leu Arg Arg Leu Phe Arg Phe Arg Gln Met Asp
                  35                  40                  45

 Phe Glu Phe Ala Ala Trp Gln Met Leu Tyr Leu Phe Thr Ser Pro
                  50                  55                  60

 Gln Arg Val Tyr Arg Asn Phe His Tyr Arg Lys Gln Thr Lys Asp
                  65                  70                  75

 Gln Trp Ala Arg Asp Asp Pro Ala Phe Leu Val Leu Leu Ser Ile
                  80                  85                  90

 Trp Leu Cys Val Ser Thr Ile Gly Phe Gly Phe Val Leu Asp Met
                  95                 100                 105

 Gly Phe Phe Glu Thr Ile Lys Leu Leu Leu Trp Val Val Leu Ile
                 110                 115                 120

 Asp Cys Val Gly Val Gly Leu Leu Ile Ala Thr Leu Met Trp Phe
                 125                 130                 135

 Ile Ser Asn Lys Tyr Leu Val Lys Arg Gln Ser Arg Asp Tyr Asp
                 140                 145                 150

 Val Glu Trp Gly Tyr Ala Phe Asp Val His Leu Asn Ala Phe Tyr
                 155                 160                 165

 Pro Leu Leu Val Ile Leu His Phe Ile Gln Leu Phe Phe Ile Asn
                 170                 175                 180

 His Val Ile Leu Thr Asp Thr Phe Ile Gly Tyr Leu Val Gly Asn
                 185                 190                 195

 Thr Leu Trp Leu Val Ala Val Gly Tyr Tyr Ile Tyr Val Thr Phe
                 200                 205                 210

 Leu Gly Tyr Ser Ala Leu Pro Phe Leu Lys Asn Thr Val Ile Leu
                 215                 220                 225

 Leu Tyr Pro Phe Ala Pro Leu Ile Leu Leu Tyr Gly Leu Ser Leu
                 230                 235                 240

 Ala Leu Gly Trp Asn Phe Thr His Thr Leu Cys Ser Phe Tyr Lys
                 245                 250                 255

 Tyr Arg Val Lys


<210> 5789
<211> 10011
<212> DNA
<213> Homo sapien

<400> 5789
 ttcctccgcg aaggctcctt tgatattaat agtgttggtg tcttgaaact 50

 gacgtaatgc gcggagactg aggtcctgac aagcgataac atttctgata 100

 aagacccgat cttactgcaa tctctagcgt cctctttttt ggtgctgctg 150

 gtttctccag acctcgcgtc ctctcgattg ctctctcgcc ttcctatttc 200

 tttttttttt ttttaaacaa aaaacaacac cccctcccct ctcccacccg 250

 gcaccgggca catccttgct ctatttcctt tctctttctc tctctctctc 300

 tctctttttt aataagggtg ggggagggaa agggggggga ggcaggaaag 350

 acctttttct ctcccccccg caataatcca agatcaactc tgcaaacaac 400

 agaagacggt tcatggcttt ggccgccgcg ccaccatctt tcgggctgcc 450

 gagggtgttc ttgacgatta atcaacagat gtacagatca gctctcaaaa 500

 tgtcttctgt gtcttctgag cgtcttctaa gacaattgca ttagcctcct 550

 gctagttgac taatagaatt aataattgta aaaagcactc taaagccaca 600

 tgccttatga agtcaatgct gggtatgatt ttacaaatat ggtccggaaa 650

 aagaaccccc ctctgagaaa cgttgcaagt gaaggcgagg gccagatcct 700

 ggagcctata ggtacagaaa gcaaggtatc tggaaagaac aaagaattct 750

 ctgcagatca gatgtcagaa aatacggatc agagtgatgc tgcagaacta 800

 aatcataagg aggaacatag cttgcatgtt caagatccat cttctagcag 850

 taagaaggac ttgaaaagcg cagttctgag tgagaaggct ggcttcaatt 900

 atgaaagccc cagtaaggga ggaaactttc cctcctttcc gcatgatgag 950

 gtgacagaca gaaatatgtt ggctttctca tttccagctg ctgggggagt 1000

 ctgtgagccc ttgaagtctc cgcaaagagc agaggcagat gaccctcaag 1050

 atatggcctg caccccctca ggggactcac tggagacaaa ggaagatcag 1100

 aagatgtcac caaaggctac agaggaaaca gggcaagcac agagtggtca 1150

 agccaattgt caaggtttga gcccagtttc agtggcctca aaaaacccac 1200

 aagtgccttc agatgggggt gtaagactga ataaatccaa aactgactta 1250

 ctggtgaatg acaacccaga cccggcacct ctgtctccag agcttcagga 1300

 ctttaaatgc aatatctgtg gatatggtta ctacggcaac gaccccacag 1350

 atctgattaa gcacttccga aagtatcact taggactgca taaccgcacc 1400

 aggcaagatg ctgagctgga cagcaaaatc ttggcccttc ataacatggt 1450

 gcagttcagc cattccaaag acttccagaa ggtcaaccgt tctgtgtttt 1500

 ctggtgtgct gcaggacatc aattcttcaa ggcctgtttt actaaatggg 1550

 acctatgatg tgcaggtgac ttcaggtgga acattcattg gcattggacg 1600

 gaaaacacca gattgccaag ggaacaccaa gtatttccgc tgtaaattct 1650

 gcaatttcac ttatatgggc aactcatcca ccgaattaga acaacatttt 1700

 cttcagactc acccaaacaa aataaaagct tctctcccct cctctgaggt 1750

 tgcaaaacct tcagagaaaa actctaacaa gtccatccct gcacttcaat 1800

 ccagtgattc tggagacttg ggaaaatggc aggacaagat aacagtcaaa 1850

 gcaggagatg acactcctgt tgggtactca gtgcccataa agcccctcga 1900

 ttcctctaga caaaatggta cagaggccac cagttactac tggtgtaaat 1950

 tttgtagttt cagctgtgag tcatctagct cacttaaact gctagaacat 2000

 tatggcaagc agcacggagc agtgcagtca ggcggcctta atccagagtt 2050

 aaatgataag ctttccaggg gctctgtcat taatcagaat gatctagcca 2100

 aaagttcaga aggagagaca atgaccaaga cagacaagag ctcgagtggg 2150

 gctaaaaaga aggacttctc cagcaaggga gccgaggata atatggtaac 2200

 gagctataat tgtcagttct gtgacttccg atattccaaa agccatggcc 2250

 ctgatgtaat tgtagtgggg ccacttctcc gtcattatca acagctccat 2300

 aacattcaca agtgtaccat taaacactgt ccattctgtc ccagaggact 2350

 ttgcagccca gaaaagcacc ttggagaaat tacttatccg tttgcttgta 2400

 gaaaaagtaa ttgttcccac tgtgcactct tgcttctgca cttgtctcct 2450

 ggggcggctg gaagctcgcg agtcaaacat cagtgccatc agtgttcatt 2500

 caccacccct gacgtagatg tactcctctt tcactatgaa agtgtgcatg 2550

 agtcccaagc atcggatgtc aaacaagaag caaatcacct gcaaggatcg 2600

 gatgggcagc agtctgtcaa ggaaagcaaa gaacactcat gtaccaaatg 2650

 tgattttatt acccaagtgg aagaagagat ttcccgacac tacaggagag 2700

 cacacagctg ctacaaatgc cgtcagtgca gttttacagc tgccgatact 2750

 cagtcactac tggagcactt caacactgtt cactgccagg aacaggacat 2800

 cactacagcc aacggcgaag aggacggtca tgccatatcc accatcaaag 2850

 aggagcccaa aattgacttc agggtctaca atctgctaac tccagactct 2900

 aaaatgggag agccagtttc tgagagtgtg gtgaagagag agaagctgga 2950

 agagaaggac gggctcaaag agaaagtttg gaccgagagt tccagtgatg 3000

 accttcgcaa tgtgacttgg agaggggcag acatcctgcg ggggagtccg 3050

 tcatacaccc aagcaagcct ggggctgctg acgcctgtgt ctggcaccca 3100

 agagcagaca aagactctaa gggatagtcc caatgtggag gccgcccatc 3150

 tggcgcgacc tatttatggc ttggctgtgg aaaccaaggg attcctgcag 3200

 ggggcgccag ctggcggaga gaagtctggg gccctccccc agcagtatcc 3250

 tgcatcggga gaaaacaagt ccaaggatga atcccagtcc ctgttacgga 3300

 ggcgtagagg ctccggtgtt ttttgtgcca attgcctgac cacaaagacc 3350

 tctctctggc gaaagaatgc aaatggcgga tatgtatgca acgcgtgtgg 3400

 cctctaccag aagcttcact cgactcccag gcctttaaac atcattaaac 3450

 aaaacaacgg tgagcagatt attaggagga gaacaagaaa gcgccttaac 3500

 ccagaggcac ttcaggctga gcagctcaac aaacagcaga ggggcagcaa 3550

 tgaggagcaa gtcaatggaa gcccgttaga gaggaggtca gaagatcatc 3600

 taactgaaag tcaccagaga gaaattccac tccccagcct aagtaaatac 3650

 gaagcccagg gttcattgac taaaagccat tctgctcagc agccagtcct 3700

 ggtcagccaa actctggata ttcacaaaag gatgcaacct ttgcacattc 3750

 agataaaaag tcctcaggaa agtactggag atccaggaaa tagttcatcc 3800

 gtatctgaag ggaaaggaag ttctgagaga ggcagtccta tagaaaagta 3850

 catgagacct gcgaaacacc caaattattc accaccaggc agccctattg 3900

 aaaagtacca gtacccactt tttggacttc cctttgtaca taatgacttc 3950

 cagagtgaag ctgattggct gcggttctgg agtaaatata agctctccgt 4000

 tcctgggaat ccgcactact tgagtcacgt gcctggccta ccaaatcctt 4050

 gccaaaacta tgtgccttat cccaccttca atctgcctcc tcatttttca 4100

 gctgttggat cagacaatga cattcctcta gatttggcga tcaagcattc 4150

 cagacctggg ccaactgcaa acggtgcctc caaggagaaa acgaaggcac 4200

 caccaaatgt aaaaaatgaa ggtcccttga atgtagtaaa aacagagaaa 4250

 gttgatagaa gtactcaaga tgaactttca acaaaatgtg tgcactgtgg 4300

 cattgtcttt ctggatgaag tgatgtatgc tttgcatatg agttgccatg 4350

 gtgacagtgg acctttccag tgcagcatat gccagcatct ttgcacggac 4400

 aaatatgact tcacaacaca tatccagagg ggcctgcata ggaacaatgc 4450

 acaagtggaa aaaaatggaa aacctaaaga gtaaaacctt agcacttagc 4500

 acaattaaat agaaataggt tttcttgatg ggaattcaat agcttgtaat 4550

 gtcttatgaa gacctattaa aaaaatactt catagagcct gccttatcca 4600

 acatgaaatt cccttctttt gttattcttt cttttgatga gtaggttacc 4650

 aagattaaaa agtgagataa atggtcaatg agaaagaatg gaagatggta 4700

 aacaatcact ttttaaaacc tgttaagtca aaaccatctt ggctaatatg 4750

 tactggggaa ataatccata agagatatca ccagactaga attaatatat 4800

 ttataaagaa agagaccaaa actgtctaga atttgaaagg gtttacatat 4850

 tattatacta aagcagtact ggactggcca ttggaccatt tgttccaaaa 4900

 cccataaatt gttgcctaaa tttataatga tcatgaaacc ctaggcagag 4950

 gaggagaaat tgaaggtcca gggcaatgaa agaaaaatgg cgccctctca 5000

 atttagtctt ctctcattgg ccatgtttca gattttgacc tagaaatgcg 5050

 agctgtggtt aggcttggtt agagtgcagc aagcaacatg acagatggtg 5100

 gcacgctgtt tttacccagc cctgcctgta catacacatg cacaccctct 5150

 ctgatatttt tgtcctttag atgttcaaat actcagtagt ccttttgttt 5200

 gcggtttaga ttcattttgt ccacacatgt acccatttta aaaaacaatg 5250

 tcctcgatgc ttctgtagtg atttcatttt agccaggtat ttctttcttg 5300

 tgtgtgatga accagtatgg atttgctttt ctaagcctcc tgttggttac 5350

 taatctcact tggcacatta taactaaagg aatcccctca attcaaaagc 5400

 atagatggat acaaatgtca gaccgtgggt ttaatttgtt tagaacacat 5450

 ggcatttctt cacaaggtaa cctgctgtat ttatttattt tcttttggtt 5500

 aaatataatt tccaaacttt gtggtcaggc agcgtctaag gttacgttac 5550

 cacagactga cagttggtat atgtaccagc caatcccttc attaaatgta 5600

 tacagattta gttaagtagc attaaatagg attcttagaa gtatgtcctc 5650

 atagaacttt taatacttaa ggctttgtaa aaactatcca tgaagggaaa 5700

 gctcctcagc ataactgctc agggaaatag ggctaaataa ctgaacatta 5750

 aataattggt taaaggtgct gttagtcgag cctcaatgct tgctacaagg 5800

 atgtatgtac aaggactgac tttaataatt tgcattatat tgtcccaacc 5850

 agtagtttat tttttgccac ggagatgtag aagatattac aagctactgg 5900

 atgcactgtc agattaactt atttcattaa agaagttggg agaacaaata 5950

 ggaaaaaaaa aacttatttt tctagtaaat attaatgtat tacatttcaa 6000

 ataatggtgc ctgacatatt gaataattat tttctacagt gtacgtatgc 6050

 aacaaagata ttccatcatg cattagagtc agttctggct ctgcctagct 6100

 gtttacattt gcaaatgtag caaacaaggt aatgaagcaa ctatttctat 6150

 tgcagtagat atccttttgt gtgtgtgtgt gtgcattaaa gttgtaaacg 6200

 gtaacatgaa acaaatgaaa gttcttgcta taatggtatg gaaaacaaga 6250

 aggaaatgaa aatattttta tgcctactta ggaaaaaaag ggtagcactt 6300

 attcattcca agtacttttt tttttttaat ttttaagctc ttaactcaca 6350

 ttgttatgct taagatgata aacatatatc ctctttttat tgctttgtct 6400

 atgtttcata tgaaacattt cagaaattat tttgataagt gttgctggaa 6450

 tctgcaacgc tgattttttt ttgcattctg tagtcgcatt tgcactccat 6500

 ttttacatta attcgcagtt gctttgtatc attgttttgt ttgggttttg 6550

 tttctttttc acagtgccgg gtcttcgttt cttaaagttg gatggcaggt 6600

 agagttcaac cagttcgtga ctgttgtagc gaatgaagtt aaaaaaatgt 6650

 ctttctgatg ttgtgttgtc attttcattt ttgcattttt ttgtttgcat 6700

 attaaaaaaa gagaaaagag aaagcaagag acagaaatca ggactaagtc 6750

 ctctgcttca gtttcattgt taacgggcct tattctgatc tcacctgtcg 6800

 cgtagctcta atattcacat aaactgaaat aaagaagtgg aatgaggagc 6850

 tttgacattc aaattatgtg atgtaattta tcttccttag gaattttgat 6900

 ggatgcatct caaaatgtat agccagactt gagaggtgac aattaaagat 6950

 ctaaaaaaga gaggagattc ccccaaacaa caatatttaa ttttcttagt 7000

 aaaaagaata acagaatgca tcgtggcaat ccttaagcaa cattatctat 7050

 gtggactgct taaatcagca aaacaccaga agtttggtta acttgggcaa 7100

 tatgacaagt attacttttt gggcaaaact actcattaag caatttctct 7150

 agtgtgtcgg acacaaatag gttctttatt tttggcatgt atgccttttt 7200

 attttcattc aatttttttt ttttctcaga cagacatagt agtatcaact 7250

 agcattggaa aatacatatc actattcttg gaatatttat ggtcagtcta 7300

 ctttttagta aaatattttt ggatagcgtt gacacgatag atcttattcc 7350

 atacttcttt attattgata attttatttt cattttttgc tttcattatt 7400

 atacatattt tggtggagaa gaggttgggc ttttttgaaa gagacaaaaa 7450

 tttattataa cactaaacac tccttttttg acatattaaa gcctttattc 7500

 catctctcaa gatatattat aaaatttatt tttttaattt aagatttctg 7550

 aattatttta tcttaaattg tgattttaaa cgagctatta tggtacggaa 7600

 ctttttttaa tgaggaattt catgatgatt taggaatttt ctctcttgga 7650

 aaaggcttcc cctgtgatga aaatgatgtg ccagctaaaa ttgtgtgcca 7700

 tttaaaaact gaaaatattt taaaattatt tgtctatatt ctaaattgag 7750

 ctttggatca aactttaggc caggaccagc tcatgcgttc tcattcttcc 7800

 ttttctcact ctttctctca tcactcacct ctgtattcat tctgttgttt 7850

 gggatagaaa aatcataaag agccaaccca tctcagaacg ttgtggattg 7900

 agagagacac tacatgactc caagtatatg agaaaaggac agagctctaa 7950

 ttgataactc tgtagttcaa aaggaaaaga gtatgcccaa ttctctctac 8000

 atgacatatt gagatttttt ttaatcaact tttaagatag tgatgttctg 8050

 ttctaaactg ttctgtttta gtgaaggtag atttttataa aacaagcatg 8100

 gggattcttt tctaaggtaa tattaatgag aagggaaaaa agtatcttta 8150

 acagctcttt gttgaagcct gtggtagcac attatgttta taattgcaca 8200

 tgtgcacata atctattatg atccaatgca aatacagctc caaaaatatt 8250

 aaatgtatat atattttaaa atgcctgagg aaatacattt ttcttaataa 8300

 actgaagagt ctcagtatgg ctattaaaat aattattagc ctcctgttgt 8350

 gtggctgcaa aacatcacaa agtgaccggt cttgagacct gtgaactgct 8400

 gccctgttta gtaaataaaa ttaatgcatt tctagagggg gaatatctgc 8450

 catccagtgg tggaaatgtg gagtaaagaa gctggtggtc tgcttctgtg 8500

 ctgtatgcca gccttttgcc ttaagttgag aggaggtcaa ctttagctac 8550

 tgtctttggt ttgagagcca tggcaaaaaa aaaaaaagaa aaaaagatca 8600

 agtcgtcttt ggtgagccag taaggtgaaa gcttgctgac tgtccaaggc 8650

 acaagagaaa attgaggaat tgaaatgcaa cctgagtatc aaactaaata 8700

 ttctaatcaa aggtaggtac tgttaggtgg aattctatca gcaggcaact 8750

 gcaaatgaga agaagataga aggacgcccg tcgggacttt ggagggcatt 8800

 gttattttcc caaagaaaga cggccaaggg cagaggcatg gattctttgc 8850

 agagcacttc cttttggttt ttcagtactg tttcatagac agtgggctca 8900

 catgttcctg atagtgctgc agttgcttag aaagcatccc agttaattgc 8950

 agtaattaga acttctggaa tatgctaggg cagaagtatg tcaagtatgt 9000

 cacatgaaga aaatgtgaaa ttcaagagta atccacacgt gagaaactag 9050

 acaatgtaca ttcatgtgtt ctcttgaaag gaaagggaga gctgtaagct 9100

 tcactctgtc ctacaccgga gaaaagcagg aataacttta ccgtggaaat 9150

 aatgtttagc ttttatcaga gaaaattgtc cttctagagc atagagtccc 9200

 aaaactcaat tctggttttc ccctgttttt tttttttttt tttttcccaa 9250

 catatgaact gcagcatatc actttttctt tttgtgcctc aggttcctca 9300

 cctgtaaaat tgaaaaatat atgtattaat aatattatta ataataataa 9350

 tggtaatgta gtacttgttt gtaaagcact ttgagatcct tggttgaaag 9400

 gcaccatagg agtgccaagt attattatgt ggccaagggg gttatttaaa 9450

 ctgtcagttc ccaaaggcca ggaaaggttg gggtcatttt tcttaaagac 9500

 gagctgtaaa tatcaactag gcagccaata gtgttgacta tgaagatgca 9550

 aaactattac taggctgata aaatcatagt ttcttaatgg ctaccaataa 9600

 ggcaaatatc acaataataa acgccaaatt ccttagggcg gactatttga 9650

 caaccacatg gaaaactttg ggggaggcat gaggggggaa catctcaaaa 9700

 tgccaatgta aaatttaact tacagcaata ttcaccagca gaaaatgtct 9750

 ttcatatgga atgatttcat gttgctaaga aaaagaattc aatttgtagt 9800

 cctgatttga atactagaat gttggctata atagttctgt tcttacaaca 9850

 catgaaattt tttcgtttta ttttattttg ttttcatagt gcatgttcat 9900

 ttctactcac aaacatgttc ttggtgtatt tcttatgcaa acaatcttca 9950

 ggcagcaaag atgtctgtta catctaaact tgaataataa agttttacca 10000

 ccagttacac a 10011

<210> 5790
<211> 1281
<212> PRT
<213> Homo sapien

<400> 5790
 Met Val Arg Lys Lys Asn Pro Pro Leu Arg Asn Val Ala Ser Glu
   1               5                  10                  15

 Gly Glu Gly Gln Ile Leu Glu Pro Ile Gly Thr Glu Ser Lys Val
                  20                  25                  30

 Ser Gly Lys Asn Lys Glu Phe Ser Ala Asp Gln Met Ser Glu Asn
                  35                  40                  45

 Thr Asp Gln Ser Asp Ala Ala Glu Leu Asn His Lys Glu Glu His
                  50                  55                  60

 Ser Leu His Val Gln Asp Pro Ser Ser Ser Ser Lys Lys Asp Leu
                  65                  70                  75

 Lys Ser Ala Val Leu Ser Glu Lys Ala Gly Phe Asn Tyr Glu Ser
                  80                  85                  90

 Pro Ser Lys Gly Gly Asn Phe Pro Ser Phe Pro His Asp Glu Val
                  95                 100                 105

 Thr Asp Arg Asn Met Leu Ala Phe Ser Phe Pro Ala Ala Gly Gly
                 110                 115                 120

 Val Cys Glu Pro Leu Lys Ser Pro Gln Arg Ala Glu Ala Asp Asp
                 125                 130                 135

 Pro Gln Asp Met Ala Cys Thr Pro Ser Gly Asp Ser Leu Glu Thr
                 140                 145                 150

 Lys Glu Asp Gln Lys Met Ser Pro Lys Ala Thr Glu Glu Thr Gly
                 155                 160                 165

 Gln Ala Gln Ser Gly Gln Ala Asn Cys Gln Gly Leu Ser Pro Val
                 170                 175                 180

 Ser Val Ala Ser Lys Asn Pro Gln Val Pro Ser Asp Gly Gly Val
                 185                 190                 195

 Arg Leu Asn Lys Ser Lys Thr Asp Leu Leu Val Asn Asp Asn Pro
                 200                 205                 210

 Asp Pro Ala Pro Leu Ser Pro Glu Leu Gln Asp Phe Lys Cys Asn
                 215                 220                 225

 Ile Cys Gly Tyr Gly Tyr Tyr Gly Asn Asp Pro Thr Asp Leu Ile
                 230                 235                 240

 Lys His Phe Arg Lys Tyr His Leu Gly Leu His Asn Arg Thr Arg
                 245                 250                 255

 Gln Asp Ala Glu Leu Asp Ser Lys Ile Leu Ala Leu His Asn Met
                 260                 265                 270

 Val Gln Phe Ser His Ser Lys Asp Phe Gln Lys Val Asn Arg Ser
                 275                 280                 285

 Val Phe Ser Gly Val Leu Gln Asp Ile Asn Ser Ser Arg Pro Val
                 290                 295                 300

 Leu Leu Asn Gly Thr Tyr Asp Val Gln Val Thr Ser Gly Gly Thr
                 305                 310                 315

 Phe Ile Gly Ile Gly Arg Lys Thr Pro Asp Cys Gln Gly Asn Thr
                 320                 325                 330

 Lys Tyr Phe Arg Cys Lys Phe Cys Asn Phe Thr Tyr Met Gly Asn
                 335                 340                 345

 Ser Ser Thr Glu Leu Glu Gln His Phe Leu Gln Thr His Pro Asn
                 350                 355                 360

 Lys Ile Lys Ala Ser Leu Pro Ser Ser Glu Val Ala Lys Pro Ser
                 365                 370                 375

 Glu Lys Asn Ser Asn Lys Ser Ile Pro Ala Leu Gln Ser Ser Asp
                 380                 385                 390

 Ser Gly Asp Leu Gly Lys Trp Gln Asp Lys Ile Thr Val Lys Ala
                 395                 400                 405

 Gly Asp Asp Thr Pro Val Gly Tyr Ser Val Pro Ile Lys Pro Leu
                 410                 415                 420

 Asp Ser Ser Arg Gln Asn Gly Thr Glu Ala Thr Ser Tyr Tyr Trp
                 425                 430                 435

 Cys Lys Phe Cys Ser Phe Ser Cys Glu Ser Ser Ser Ser Leu Lys
                 440                 445                 450

 Leu Leu Glu His Tyr Gly Lys Gln His Gly Ala Val Gln Ser Gly
                 455                 460                 465

 Gly Leu Asn Pro Glu Leu Asn Asp Lys Leu Ser Arg Gly Ser Val
                 470                 475                 480

 Ile Asn Gln Asn Asp Leu Ala Lys Ser Ser Glu Gly Glu Thr Met
                 485                 490                 495

 Thr Lys Thr Asp Lys Ser Ser Ser Gly Ala Lys Lys Lys Asp Phe
                 500                 505                 510

 Ser Ser Lys Gly Ala Glu Asp Asn Met Val Thr Ser Tyr Asn Cys
                 515                 520                 525

 Gln Phe Cys Asp Phe Arg Tyr Ser Lys Ser His Gly Pro Asp Val
                 530                 535                 540

 Ile Val Val Gly Pro Leu Leu Arg His Tyr Gln Gln Leu His Asn
                 545                 550                 555

 Ile His Lys Cys Thr Ile Lys His Cys Pro Phe Cys Pro Arg Gly
                 560                 565                 570

 Leu Cys Ser Pro Glu Lys His Leu Gly Glu Ile Thr Tyr Pro Phe
                 575                 580                 585

 Ala Cys Arg Lys Ser Asn Cys Ser His Cys Ala Leu Leu Leu Leu
                 590                 595                 600

 His Leu Ser Pro Gly Ala Ala Gly Ser Ser Arg Val Lys His Gln
                 605                 610                 615

 Cys His Gln Cys Ser Phe Thr Thr Pro Asp Val Asp Val Leu Leu
                 620                 625                 630

 Phe His Tyr Glu Ser Val His Glu Ser Gln Ala Ser Asp Val Lys
                 635                 640                 645

 Gln Glu Ala Asn His Leu Gln Gly Ser Asp Gly Gln Gln Ser Val
                 650                 655                 660

 Lys Glu Ser Lys Glu His Ser Cys Thr Lys Cys Asp Phe Ile Thr
                 665                 670                 675

 Gln Val Glu Glu Glu Ile Ser Arg His Tyr Arg Arg Ala His Ser
                 680                 685                 690

 Cys Tyr Lys Cys Arg Gln Cys Ser Phe Thr Ala Ala Asp Thr Gln
                 695                 700                 705

 Ser Leu Leu Glu His Phe Asn Thr Val His Cys Gln Glu Gln Asp
                 710                 715                 720

 Ile Thr Thr Ala Asn Gly Glu Glu Asp Gly His Ala Ile Ser Thr
                 725                 730                 735

 Ile Lys Glu Glu Pro Lys Ile Asp Phe Arg Val Tyr Asn Leu Leu
                 740                 745                 750

 Thr Pro Asp Ser Lys Met Gly Glu Pro Val Ser Glu Ser Val Val
                 755                 760                 765

 Lys Arg Glu Lys Leu Glu Glu Lys Asp Gly Leu Lys Glu Lys Val
                 770                 775                 780

 Trp Thr Glu Ser Ser Ser Asp Asp Leu Arg Asn Val Thr Trp Arg
                 785                 790                 795

 Gly Ala Asp Ile Leu Arg Gly Ser Pro Ser Tyr Thr Gln Ala Ser
                 800                 805                 810

 Leu Gly Leu Leu Thr Pro Val Ser Gly Thr Gln Glu Gln Thr Lys
                 815                 820                 825

 Thr Leu Arg Asp Ser Pro Asn Val Glu Ala Ala His Leu Ala Arg
                 830                 835                 840

 Pro Ile Tyr Gly Leu Ala Val Glu Thr Lys Gly Phe Leu Gln Gly
                 845                 850                 855

 Ala Pro Ala Gly Gly Glu Lys Ser Gly Ala Leu Pro Gln Gln Tyr
                 860                 865                 870

 Pro Ala Ser Gly Glu Asn Lys Ser Lys Asp Glu Ser Gln Ser Leu
                 875                 880                 885

 Leu Arg Arg Arg Arg Gly Ser Gly Val Phe Cys Ala Asn Cys Leu
                 890                 895                 900

 Thr Thr Lys Thr Ser Leu Trp Arg Lys Asn Ala Asn Gly Gly Tyr
                 905                 910                 915

 Val Cys Asn Ala Cys Gly Leu Tyr Gln Lys Leu His Ser Thr Pro
                 920                 925                 930

 Arg Pro Leu Asn Ile Ile Lys Gln Asn Asn Gly Glu Gln Ile Ile
                 935                 940                 945

 Arg Arg Arg Thr Arg Lys Arg Leu Asn Pro Glu Ala Leu Gln Ala
                 950                 955                 960

 Glu Gln Leu Asn Lys Gln Gln Arg Gly Ser Asn Glu Glu Gln Val
                 965                 970                 975

 Asn Gly Ser Pro Leu Glu Arg Arg Ser Glu Asp His Leu Thr Glu
                 980                 985                 990

 Ser His Gln Arg Glu Ile Pro Leu Pro Ser Leu Ser Lys Tyr Glu
                 995                1000                1005

 Ala Gln Gly Ser Leu Thr Lys Ser His Ser Ala Gln Gln Pro Val
                1010                1015                1020

 Leu Val Ser Gln Thr Leu Asp Ile His Lys Arg Met Gln Pro Leu
                1025                1030                1035

 His Ile Gln Ile Lys Ser Pro Gln Glu Ser Thr Gly Asp Pro Gly
                1040                1045                1050

 Asn Ser Ser Ser Val Ser Glu Gly Lys Gly Ser Ser Glu Arg Gly
                1055                1060                1065

 Ser Pro Ile Glu Lys Tyr Met Arg Pro Ala Lys His Pro Asn Tyr
                1070                1075                1080

 Ser Pro Pro Gly Ser Pro Ile Glu Lys Tyr Gln Tyr Pro Leu Phe
                1085                1090                1095

 Gly Leu Pro Phe Val His Asn Asp Phe Gln Ser Glu Ala Asp Trp
                1100                1105                1110

 Leu Arg Phe Trp Ser Lys Tyr Lys Leu Ser Val Pro Gly Asn Pro
                1115                1120                1125

 His Tyr Leu Ser His Val Pro Gly Leu Pro Asn Pro Cys Gln Asn
                1130                1135                1140

 Tyr Val Pro Tyr Pro Thr Phe Asn Leu Pro Pro His Phe Ser Ala
                1145                1150                1155

 Val Gly Ser Asp Asn Asp Ile Pro Leu Asp Leu Ala Ile Lys His
                1160                1165                1170

 Ser Arg Pro Gly Pro Thr Ala Asn Gly Ala Ser Lys Glu Lys Thr
                1175                1180                1185

 Lys Ala Pro Pro Asn Val Lys Asn Glu Gly Pro Leu Asn Val Val
                1190                1195                1200

 Lys Thr Glu Lys Val Asp Arg Ser Thr Gln Asp Glu Leu Ser Thr
                1205                1210                1215

 Lys Cys Val His Cys Gly Ile Val Phe Leu Asp Glu Val Met Tyr
                1220                1225                1230

 Ala Leu His Met Ser Cys His Gly Asp Ser Gly Pro Phe Gln Cys
                1235                1240                1245

 Ser Ile Cys Gln His Leu Cys Thr Asp Lys Tyr Asp Phe Thr Thr
                1250                1255                1260

 His Ile Gln Arg Gly Leu His Arg Asn Asn Ala Gln Val Glu Lys
                1265                1270                1275

 Asn Gly Lys Pro Lys Glu
                1280

<210> 5791
<211> 3429
<212> DNA
<213> Homo sapien

<400> 5791
 ggctggaagc cggaagcgag caaagtggag ccgactcgaa ctccaccggc 50

 acgagggcgg aaaagaaagc ctcagaacgt tcgctcgctg cgtccccagc 100

 cggggccgag ccctccgcga cgccacccgg gccatggggg ccgcacgcag 150

 cccgccgtcc gctgtcccgg ggcccctgct ggggctgctc ctgctgctcc 200

 tgggcgtgct ggccccgggt ggcgcctccc tgcgactcct ggaccaccgg 250

 gcgctggtct gctcccagcc ggggctaaac tgcacggtca agaatagtac 300

 ctgcctggat gacagctgga ttcaccctcg aaacctgacc ccctcctccc 350

 caaaggacct gcagatccag ctgcactttg cccacaccca acaaggagac 400

 ctgttccccg tggctcacat cgaatggaca ctgcagacag acgccagcat 450

 cctgtacctc gagggtgcag agttatctgt cctgcagctg aacaccaatg 500

 aacgtttgtg cgtcaggttt gagtttctgt ccaaactgag gcatcaccac 550

 aggcggtggc gttttacctt cagccacttt gtggttgacc ctgaccagga 600

 atatgaggtg accgttcacc acctgcccaa gcccatccct gatggggacc 650

 caaaccacca gtccaagaat ttccttgtgc ctgactgtga gcacgccagg 700

 atgaaggtaa ccacgccatg catgagctca ggcagcctgt gggaccccaa 750

 catcaccgtg gagaccctgg aggcccacca gctgcgtgtg agcttcaccc 800

 tgtggaacga atctacccat taccagatcc tgctgaccag ttttccgcac 850

 atggagaacc acagttgctt tgagcacatg caccacatac ctgcgcccag 900

 accagaagag ttccaccagc gatccaacgt cacactcact ctacgcaacc 950

 ttaaagggtg ctgtcgccac caagtgcaga tccagccctt cttcagcagc 1000

 tgcctcaatg actgcctcag acactccgcg actgtttcct gcccagaaat 1050

 gccagacact ccagaaccaa ttccggacta catgcccctg tgggtgtact 1100

 ggttcatcac gggcatctcc atcctgctgg tgggctccgt catcctgctc 1150

 atcgtctgca tgacctggag gctagctggg cctggaagtg aaaaatacag 1200

 tgatgacacc aaatacaccg atggcctgcc tgcggctgac ctgatccccc 1250

 caccgctgaa gcccaggaag gtctggatca tctactcagc cgaccacccc 1300

 ctctacgtgg acgtggtcct gaaattcgcc cagttcctgc tcaccgcctg 1350

 cggcacggaa gtggccctgg acctgctgga agagcaggcc atctcggagg 1400

 caggagtcat gacctgggtg ggccgtcaga agcaggagat ggtggagagc 1450

 aactctaaga tcatcgtcct gtgctcccgc ggcacgcgcg ccaagtggca 1500

 ggcgctcctg ggccgggggg cgcctgtgcg gctgcgctgc gaccacggaa 1550

 agcccgtggg ggacctgttc actgcagcca tgaacatgat cctcccggac 1600

 ttcaagaggc cagcctgctt cggcacctac gtagtctgct acttcagcga 1650

 ggtcagctgt gacggcgacg tccccgacct gttcggcgcg gcgccgcggt 1700

 acccgctcat ggacaggttc gaggaggtgt acttccgcat ccaggacctg 1750

 gagatgttcc agccgggccg catgcaccgc gtaggggagc tgtcggggga 1800

 caactacctg cggagcccgg gcggcaggca gctccgcgcc gccctggaca 1850

 ggttccggga ctggcaggtc cgctgtcccg actggttcga atgtgagaac 1900

 ctctactcag cagatgacca ggatgccccg tccctggacg aagaggtgtt 1950

 tgaggagcca ctgctgcctc cgggaaccgg catcgtgaag cgggcgcccc 2000

 tggtgcgcga gcctggctcc caggcctgcc tggccataga cccgctggtc 2050

 ggggaggaag gaggagcagc agtggcaaag ctggaacctc acctgcagcc 2100

 ccggggtcag ccagcgccgc agcccctcca caccctggtg ctcgccgcag 2150

 aggagggggc cctggtggcc gcggtggagc ctgggcccct ggctgacggt 2200

 gccgcagtcc ggctggcact ggcgggggag ggcgaggcct gcccgctgct 2250

 gggcagcccg ggcgctgggc gaaatagcgt cctcttcctc cccgtggacc 2300

 ccgaggactc gccccttggc agcagcaccc ccatggcgtc tcctgacctc 2350

 cttccagagg acgtgaggga gcacctcgaa ggcttgatgc tctcgctctt 2400

 cgagcagagt ctgagctgcc aggcccaggg gggctgcagt agacccgcca 2450

 tggtcctcac agacccacac acgccctacg aggaggagca gcggcagtca 2500

 gtgcagtctg accagggcta catctccagg agctccccgc agccccccga 2550

 gggactcacg gaaatggagg aagaggagga agaggagcag gacccaggga 2600

 agccggccct gccactctct cccgaggacc tggagagcct gaggagcctc 2650

 cagcggcagc tgcttttccg ccagctgcag aagaactcgg gctgggacac 2700

 gatggggtca gagtcagagg ggcccagtgc atgagggcgg ctccccaggg 2750

 accgcccaga tcccagcttt gagagaggag tgtgtgtgca cgtattcatc 2800

 tgtgtgtaca tgtctgcatg tgtatatgtt cgtgtgtgaa atgtaggctt 2850

 taaaatgtaa atgtctggat tttaatccca ggcatccctc ctaacttttc 2900

 tttgtgcagc ggtctggtta tcgtctatcc ccaggggaat ccacacagcc 2950

 cgctcccagg agctaatggt agagcgtcct tgaggctcca ttattcgttc 3000

 attcagcatt tattgtgcac ctactatgtg gcgggcattt gggataccaa 3050

 gataaattgc atgcggcatg gccccagcca tgaaggaact taaccgctag 3100

 tgccgaggac acgttaaacg aacaggatgg gccgggcacg gtggctcacg 3150

 cctgtaatcc cagcacactg ggaggccgag gcaggtggat cactctgagg 3200

 tcaggagttt gagccagcct ggccaacatg gtgaaacccc atctccacta 3250

 aaaatagaaa aattagccgg gcatggtgac acatgcctgt agtcctagct 3300

 acttgggagg ctgaggcagg agaattgctt gaatctggga ggcagaggtt 3350

 gcagtgagcc gagattgtgc cattgcactg cagcctggat gacagagcga 3400

 gactctatct caaaaaaaaa aaaaaaaaa 3429

<210> 5792
<211> 866
<212> PRT
<213> Homo sapien

<400> 5792
 Met Gly Ala Ala Arg Ser Pro Pro Ser Ala Val Pro Gly Pro Leu
   1               5                  10                  15

 Leu Gly Leu Leu Leu Leu Leu Leu Gly Val Leu Ala Pro Gly Gly
                  20                  25                  30

 Ala Ser Leu Arg Leu Leu Asp His Arg Ala Leu Val Cys Ser Gln
                  35                  40                  45

 Pro Gly Leu Asn Cys Thr Val Lys Asn Ser Thr Cys Leu Asp Asp
                  50                  55                  60

 Ser Trp Ile His Pro Arg Asn Leu Thr Pro Ser Ser Pro Lys Asp
                  65                  70                  75

 Leu Gln Ile Gln Leu His Phe Ala His Thr Gln Gln Gly Asp Leu
                  80                  85                  90

 Phe Pro Val Ala His Ile Glu Trp Thr Leu Gln Thr Asp Ala Ser
                  95                 100                 105

 Ile Leu Tyr Leu Glu Gly Ala Glu Leu Ser Val Leu Gln Leu Asn
                 110                 115                 120

 Thr Asn Glu Arg Leu Cys Val Arg Phe Glu Phe Leu Ser Lys Leu
                 125                 130                 135

 Arg His His His Arg Arg Trp Arg Phe Thr Phe Ser His Phe Val
                 140                 145                 150

 Val Asp Pro Asp Gln Glu Tyr Glu Val Thr Val His His Leu Pro
                 155                 160                 165

 Lys Pro Ile Pro Asp Gly Asp Pro Asn His Gln Ser Lys Asn Phe
                 170                 175                 180

 Leu Val Pro Asp Cys Glu His Ala Arg Met Lys Val Thr Thr Pro
                 185                 190                 195

 Cys Met Ser Ser Gly Ser Leu Trp Asp Pro Asn Ile Thr Val Glu
                 200                 205                 210

 Thr Leu Glu Ala His Gln Leu Arg Val Ser Phe Thr Leu Trp Asn
                 215                 220                 225

 Glu Ser Thr His Tyr Gln Ile Leu Leu Thr Ser Phe Pro His Met
                 230                 235                 240

 Glu Asn His Ser Cys Phe Glu His Met His His Ile Pro Ala Pro
                 245                 250                 255

 Arg Pro Glu Glu Phe His Gln Arg Ser Asn Val Thr Leu Thr Leu
                 260                 265                 270

 Arg Asn Leu Lys Gly Cys Cys Arg His Gln Val Gln Ile Gln Pro
                 275                 280                 285

 Phe Phe Ser Ser Cys Leu Asn Asp Cys Leu Arg His Ser Ala Thr
                 290                 295                 300

 Val Ser Cys Pro Glu Met Pro Asp Thr Pro Glu Pro Ile Pro Asp
                 305                 310                 315

 Tyr Met Pro Leu Trp Val Tyr Trp Phe Ile Thr Gly Ile Ser Ile
                 320                 325                 330

 Leu Leu Val Gly Ser Val Ile Leu Leu Ile Val Cys Met Thr Trp
                 335                 340                 345

 Arg Leu Ala Gly Pro Gly Ser Glu Lys Tyr Ser Asp Asp Thr Lys
                 350                 355                 360

 Tyr Thr Asp Gly Leu Pro Ala Ala Asp Leu Ile Pro Pro Pro Leu
                 365                 370                 375

 Lys Pro Arg Lys Val Trp Ile Ile Tyr Ser Ala Asp His Pro Leu
                 380                 385                 390

 Tyr Val Asp Val Val Leu Lys Phe Ala Gln Phe Leu Leu Thr Ala
                 395                 400                 405

 Cys Gly Thr Glu Val Ala Leu Asp Leu Leu Glu Glu Gln Ala Ile
                 410                 415                 420

 Ser Glu Ala Gly Val Met Thr Trp Val Gly Arg Gln Lys Gln Glu
                 425                 430                 435

 Met Val Glu Ser Asn Ser Lys Ile Ile Val Leu Cys Ser Arg Gly
                 440                 445                 450

 Thr Arg Ala Lys Trp Gln Ala Leu Leu Gly Arg Gly Ala Pro Val
                 455                 460                 465

 Arg Leu Arg Cys Asp His Gly Lys Pro Val Gly Asp Leu Phe Thr
                 470                 475                 480

 Ala Ala Met Asn Met Ile Leu Pro Asp Phe Lys Arg Pro Ala Cys
                 485                 490                 495

 Phe Gly Thr Tyr Val Val Cys Tyr Phe Ser Glu Val Ser Cys Asp
                 500                 505                 510

 Gly Asp Val Pro Asp Leu Phe Gly Ala Ala Pro Arg Tyr Pro Leu
                 515                 520                 525

 Met Asp Arg Phe Glu Glu Val Tyr Phe Arg Ile Gln Asp Leu Glu
                 530                 535                 540

 Met Phe Gln Pro Gly Arg Met His Arg Val Gly Glu Leu Ser Gly
                 545                 550                 555

 Asp Asn Tyr Leu Arg Ser Pro Gly Gly Arg Gln Leu Arg Ala Ala
                 560                 565                 570

 Leu Asp Arg Phe Arg Asp Trp Gln Val Arg Cys Pro Asp Trp Phe
                 575                 580                 585

 Glu Cys Glu Asn Leu Tyr Ser Ala Asp Asp Gln Asp Ala Pro Ser
                 590                 595                 600

 Leu Asp Glu Glu Val Phe Glu Glu Pro Leu Leu Pro Pro Gly Thr
                 605                 610                 615

 Gly Ile Val Lys Arg Ala Pro Leu Val Arg Glu Pro Gly Ser Gln
                 620                 625                 630

 Ala Cys Leu Ala Ile Asp Pro Leu Val Gly Glu Glu Gly Gly Ala
                 635                 640                 645

 Ala Val Ala Lys Leu Glu Pro His Leu Gln Pro Arg Gly Gln Pro
                 650                 655                 660

 Ala Pro Gln Pro Leu His Thr Leu Val Leu Ala Ala Glu Glu Gly
                 665                 670                 675

 Ala Leu Val Ala Ala Val Glu Pro Gly Pro Leu Ala Asp Gly Ala
                 680                 685                 690

 Ala Val Arg Leu Ala Leu Ala Gly Glu Gly Glu Ala Cys Pro Leu
                 695                 700                 705

 Leu Gly Ser Pro Gly Ala Gly Arg Asn Ser Val Leu Phe Leu Pro
                 710                 715                 720

 Val Asp Pro Glu Asp Ser Pro Leu Gly Ser Ser Thr Pro Met Ala
                 725                 730                 735

 Ser Pro Asp Leu Leu Pro Glu Asp Val Arg Glu His Leu Glu Gly
                 740                 745                 750

 Leu Met Leu Ser Leu Phe Glu Gln Ser Leu Ser Cys Gln Ala Gln
                 755                 760                 765

 Gly Gly Cys Ser Arg Pro Ala Met Val Leu Thr Asp Pro His Thr
                 770                 775                 780

 Pro Tyr Glu Glu Glu Gln Arg Gln Ser Val Gln Ser Asp Gln Gly
                 785                 790                 795

 Tyr Ile Ser Arg Ser Ser Pro Gln Pro Pro Glu Gly Leu Thr Glu
                 800                 805                 810

 Met Glu Glu Glu Glu Glu Glu Glu Gln Asp Pro Gly Lys Pro Ala
                 815                 820                 825

 Leu Pro Leu Ser Pro Glu Asp Leu Glu Ser Leu Arg Ser Leu Gln
                 830                 835                 840

 Arg Gln Leu Leu Phe Arg Gln Leu Gln Lys Asn Ser Gly Trp Asp
                 845                 850                 855

 Thr Met Gly Ser Glu Ser Glu Gly Pro Ser Ala
                 860                 865

<210> 5793
<211> 800
<212> DNA
<213> Homo sapien

<400> 5793
 ggcaccaggt ccccggcgaa gttctgcgct ggtcggcgga gtagcaagtg 50

 gccatgggga gcctcagcgg tctgcgcctg gcagcaggaa gctgttttag 100

 gttatgtgaa agagatgttt cctcatctct aaggcttacc agaagctctg 150

 atttgaagag aataaatgga ttttgcacaa aaccacagga aagtcccgga 200

 gctccatccc gcacttacaa cagagtgcct ttacacaaac ctacggattg 250

 gcagaaaaag atcctcatat ggtcaggtcg cttcaaaaag gaagatgaaa 300

 tcccagagac tgtctcgttg gagatgcttg atgctgcaaa gaacaagatg 350

 cgagtgaaga tcagctatct aatgattgcc ctgacggtgg taggatgcat 400

 cttcatggtt attgagggca agaaggctgc ccaaagacac gagactttaa 450

 caagcttgaa cttagaaaag aaagctcgtc tgaaagagga acagctatga 500

 aggccaaaac agagtagcag aggtatccgt gttggctgga ttttgaaaat 550

 ccaggaatta tgttataacg tgcctgtatt aaaaaggatg tggtatgagg 600

 atccatttca taaagtatga tttgcccaaa cctgtaccat ttccgtattt 650

 ctgctgtaga agtagaaata aattttctta aataatgact gtgttttatt 700

 gttttgatcc aagtcaagtg tagcctctca gccttttgga gaaaaatgaa 750

 acaatttatt tcaacttgaa taccaactct tcagagaagc aggtaccata 800

<210> 5794
<211> 148
<212> PRT
<213> Homo sapien

<400> 5794
 Met Gly Ser Leu Ser Gly Leu Arg Leu Ala Ala Gly Ser Cys Phe
   1               5                  10                  15

 Arg Leu Cys Glu Arg Asp Val Ser Ser Ser Leu Arg Leu Thr Arg
                  20                  25                  30

 Ser Ser Asp Leu Lys Arg Ile Asn Gly Phe Cys Thr Lys Pro Gln
                  35                  40                  45

 Glu Ser Pro Gly Ala Pro Ser Arg Thr Tyr Asn Arg Val Pro Leu
                  50                  55                  60

 His Lys Pro Thr Asp Trp Gln Lys Lys Ile Leu Ile Trp Ser Gly
                  65                  70                  75

 Arg Phe Lys Lys Glu Asp Glu Ile Pro Glu Thr Val Ser Leu Glu
                  80                  85                  90

 Met Leu Asp Ala Ala Lys Asn Lys Met Arg Val Lys Ile Ser Tyr
                  95                 100                 105

 Leu Met Ile Ala Leu Thr Val Val Gly Cys Ile Phe Met Val Ile
                 110                 115                 120

 Glu Gly Lys Lys Ala Ala Gln Arg His Glu Thr Leu Thr Ser Leu
                 125                 130                 135

 Asn Leu Glu Lys Lys Ala Arg Leu Lys Glu Glu Gln Leu
                 140                 145

<210> 5795
<211> 1875
<212> DNA
<213> Homo sapien

<400> 5795
 agctgcggcg gccgcaggtt ccaaagcggg tccgagccgc cgccgcgcgc 50

 gcgccgcgca ctgcagcccc aggccccggc cccccaccca cgtctgcgtt 100

 gctgccccgc ctgggccagg ccccaaaggc aaggacaaag cagctgtcag 150

 ggaacctccg ccggagtcga atttacgtgc agctgccggc aaccacaggt 200

 tccaagatgg tttgcggggg cttcgcgtgt tccaagaact gcctgtgcgc 250

 cctcaacctg ctttacacct tggttagtct gctgctaatt ggaattgctg 300

 cgtggggcat tggcttcggg ctgatttcca gtctccgagt ggtcggcgtg 350

 gtcattgcag tgggcatctt cttgttcctg attgctttag tgggtctgat 400

 tggagctgta aaacatcatc aggtgttgct atttttttat atgattattc 450

 tgttacttgt atttattgtt cagttttctg tatcttgcgc ttgtttagcc 500

 ctgaaccagg agcaacaggg tcagcttctg gaggttggtt ggaacaatac 550

 ggcaagtgct cgaaatgaca tccagagaaa tctaaactgc tgtgggttcc 600

 gaagtgttaa cccaaatgac acctgtctgg ctagctgtgt taaaagtgac 650

 cactcgtgct cgccatgtgc tccaatcata ggagaatatg ctggagaggt 700

 tttgagattt gttggtggca ttggcctgtt cttcagtttt acagagatcc 750

 tgggtgtttg gctgacctac agatacagga accagaaaga cccccgcgcg 800

 aatcctagtg cattcctttg atgagaaaac aaggaagatt tcctttcgta 850

 ttatgatctt gttcactttc tgtaattttc tgttaagctc catttgccag 900

 tttaaggaag gaaacactat ctggaaaagt accttattga tagtggaatt 950

 atatattttt actctatgtt tctctacatg tttttttctt tccgttgctg 1000

 aaaaatattt gaaacttgtg gtctctgaag ctcggtggca cctggaattt 1050

 actgtattca ttgtcgggca ctgtccactg tggcctttct tagcattttt 1100

 acctgcagaa aaactttgta tggtaccact gtgttggtta tatggtgaat 1150

 ctgaacgtac atctcactgg tataattata tgtagcactg tgctgtgtag 1200

 atagttccta ctggaaaaag agtggaaatt tattaaaatc agaaagtatg 1250

 agatcctgtt atgttaaggg aaatccaaat tcccaatttt ttttggtctt 1300

 tttaggaaag atgtgttgtg gtaaaaagtg ttagtataaa aatgataatt 1350

 tacttgtagt cttttatgat tacaccaatg tattctagaa atagttatgt 1400

 cttaggaaat tgtggtttaa tttttgactt ttacaggtaa gtgcaaagga 1450

 gaagtggttt catgaaatgt tctaatgtat aataacattt accttcagcc 1500

 tccatcagaa tggaacgagt tttgagtaat caggaagtat atctatatga 1550

 tcttgatatt gttttataat aatttgaagt ctaaaagact gcatttttaa 1600

 acaagttagt attaatgcgt tggcccacgt agcaaaaaga tatttgatta 1650

 tcttaaaaat tgttaaatac cgttttcatg aaagttctca gtattgtaac 1700

 agcaacttgt caaacctaag catatttgaa tatgatctcc cataatttga 1750

 aattgaaatc gtattgtgtg gctctgtata ttctgttaaa aaattaaagg 1800

 acagaaacct ttctttgtgt atgcatgttt gaattaaaag aaagtaatgg 1850

 aagaattgat cgatgaaaaa aaaaa 1875

<210> 5796
<211> 204
<212> PRT
<213> Homo sapien

<400> 5796
 Met Val Cys Gly Gly Phe Ala Cys Ser Lys Asn Cys Leu Cys Ala
   1               5                  10                  15

 Leu Asn Leu Leu Tyr Thr Leu Val Ser Leu Leu Leu Ile Gly Ile
                  20                  25                  30

 Ala Ala Trp Gly Ile Gly Phe Gly Leu Ile Ser Ser Leu Arg Val
                  35                  40                  45

 Val Gly Val Val Ile Ala Val Gly Ile Phe Leu Phe Leu Ile Ala
                  50                  55                  60

 Leu Val Gly Leu Ile Gly Ala Val Lys His His Gln Val Leu Leu
                  65                  70                  75

 Phe Phe Tyr Met Ile Ile Leu Leu Leu Val Phe Ile Val Gln Phe
                  80                  85                  90

 Ser Val Ser Cys Ala Cys Leu Ala Leu Asn Gln Glu Gln Gln Gly
                  95                 100                 105

 Gln Leu Leu Glu Val Gly Trp Asn Asn Thr Ala Ser Ala Arg Asn
                 110                 115                 120

 Asp Ile Gln Arg Asn Leu Asn Cys Cys Gly Phe Arg Ser Val Asn
                 125                 130                 135

 Pro Asn Asp Thr Cys Leu Ala Ser Cys Val Lys Ser Asp His Ser
                 140                 145                 150

 Cys Ser Pro Cys Ala Pro Ile Ile Gly Glu Tyr Ala Gly Glu Val
                 155                 160                 165

 Leu Arg Phe Val Gly Gly Ile Gly Leu Phe Phe Ser Phe Thr Glu
                 170                 175                 180

 Ile Leu Gly Val Trp Leu Thr Tyr Arg Tyr Arg Asn Gln Lys Asp
                 185                 190                 195

 Pro Arg Ala Asn Pro Ser Ala Phe Leu
                 200

<210> 5797
<211> 1232
<212> DNA
<213> Homo sapien

<400> 5797
 gccaccacca gtattgggga tgctgagctg cggggtacgg gcctgaggag 50

 ggatgggagt aagaagtgct gtggaaaccg tcaggccatg aaccaggctg 100

 accctcggct cagagcagtg tgcttgtgga ctctcacatc tgcagccatg 150

 agcagaggcg acaactgcac ggatctactc gcactgggaa tcccctccat 200

 aacccaggcc tggggactgt gggtcctctt aggggctgtg acgctgctat 250

 ttctcatctc gctggctgca cacttgtccc agtggaccag gggccggagc 300

 aggagccatc cggggcaggg acgctctgga gagtctgtgg aagaggtccc 350

 gctgtatggg aacctgcatt atctacagac aggacggctg tctcaagacc 400

 cagagccaga ccagcaggat ccaactcttg gaggccctgc cagggctgca 450

 gaggaggtga tgtgctatac cagcctgcag ctgcggcctc ctcagggtcg 500

 gatccccggt cctggaaccc ccgtcaagta ctcggaggtg gtgctggact 550

 ctgagccaaa gtcccaggcc tcgggccccg agccggagct ctatgcctca 600

 gtatgtgccc agacccgcag ggcccgggcc tccttcccgg atcaggccta 650

 tgccaacagc cagcctgcag ccagctgaga tggagggcct ggcacagcgg 700

 ggcgtgcact gccccagccc cccgtagcag gggcatgact gtttcccaac 750

 cagcacccaa agacgggctg ccattgccaa gtcacaggat gtgatctacc 800

 ccggacttcc tatctgagct tcaagggaga catctcaggg caaagctttc 850

 gtgatggagg aggcaaagac agtagccccc tccttatttc ttttttctat 900

 ctgttcctct tagcccccaa actcccaggt tctcacttcc ttcttctgga 950

 gtttaaccag atcctcccca cccccgctcc ctcatagtct acccccacgc 1000

 ctcagtgtct cctcaggcac aggaagtggg cggtggggga ggggtaaggg 1050

 cctgacagtg ggtgggtggg tatattcctc aggagtccac agactggagt 1100

 ggacctggaa cttagagacg ggagggaccc gagcctggct tttgacctaa 1150

 gaaccctagc aggagaatac agtctccatc ctgctgtctc tgtcctgtcc 1200

 caagttttca aataaaactt tccaaaaaag tg 1232

<210> 5798
<211> 196
<212> PRT
<213> Homo sapien

<400> 5798
 Met Asn Gln Ala Asp Pro Arg Leu Arg Ala Val Cys Leu Trp Thr
   1               5                  10                  15

 Leu Thr Ser Ala Ala Met Ser Arg Gly Asp Asn Cys Thr Asp Leu
                  20                  25                  30

 Leu Ala Leu Gly Ile Pro Ser Ile Thr Gln Ala Trp Gly Leu Trp
                  35                  40                  45

 Val Leu Leu Gly Ala Val Thr Leu Leu Phe Leu Ile Ser Leu Ala
                  50                  55                  60

 Ala His Leu Ser Gln Trp Thr Arg Gly Arg Ser Arg Ser His Pro
                  65                  70                  75

 Gly Gln Gly Arg Ser Gly Glu Ser Val Glu Glu Val Pro Leu Tyr
                  80                  85                  90

 Gly Asn Leu His Tyr Leu Gln Thr Gly Arg Leu Ser Gln Asp Pro
                  95                 100                 105

 Glu Pro Asp Gln Gln Asp Pro Thr Leu Gly Gly Pro Ala Arg Ala
                 110                 115                 120

 Ala Glu Glu Val Met Cys Tyr Thr Ser Leu Gln Leu Arg Pro Pro
                 125                 130                 135

 Gln Gly Arg Ile Pro Gly Pro Gly Thr Pro Val Lys Tyr Ser Glu
                 140                 145                 150

 Val Val Leu Asp Ser Glu Pro Lys Ser Gln Ala Ser Gly Pro Glu
                 155                 160                 165

 Pro Glu Leu Tyr Ala Ser Val Cys Ala Gln Thr Arg Arg Ala Arg
                 170                 175                 180

 Ala Ser Phe Pro Asp Gln Ala Tyr Ala Asn Ser Gln Pro Ala Ala
                 185                 190                 195

 Ser


<210> 5799
<211> 1626
<212> DNA
<213> Homo sapien

<400> 5799
 agcagcggcg ggggcccgag ggattctgaa ggaagatttc cattaggtaa 50

 tttgtttaat cagtgcaagc gaaattaagg gaaaatggat gtagaaaatg 100

 agcagatact gaatgtaaac cctgcagatc ctgataactt aagtgactct 150

 ctcttttccg gtgatgaaga aaatgctggg actgaggaag taaagaatga 200

 aataaatgga aattggattt cagcatcctc cattaacgaa gctagaatta 250

 atgccaaggc aaaaaggcga ctaaggaaaa actcatcccg ggactctggc 300

 agaggcgatt cggtcagcga cagtgggagt gacgccctta gaagtggatt 350

 aactgtgcca accagtccaa agggaaggtt gctggatggg cgatccagat 400

 ctgggaaagg aaggggacta ccaaagaaag gtggtgcagg aggcaaaggt 450

 gtctggggta cacctggaca ggggtatgat gtggaggagg tggatgtgaa 500

 agatcctaac tatgatgatg accaggagaa ctgtgtttat gaaactgtag 550

 ttttgccttt ggatgaaagg gcatttgaga agactttaac accaatcata 600

 caggaatatt ttgagcatgg agatactaat gaagttgcgg aaatgttaag 650

 agatttaaat cttggtgaaa tgaaaagtgg agtaccagtg ttggcagtat 700

 ccttagcatt ggaggggaag gctagtcata gagagatgac atctaagttt 750

 ctttctgacc tttgtgggac agtaatgagc acaactgatg tggaaaaatc 800

 atttgataaa ttgttgaaag atctacctga attagcactg gatactccta 850

 gagcaccaca gttggtgggc cagtttattg ctagagctgt tggagatgga 900

 attttatgta atacctatat tgatagttac aaaggaactg tagattgtgt 950

 gcaggctaga gctgctctgg ataaggctac cgtgcttctg agtatgtcta 1000

 aaggtggaaa gcgtaaagat agtgtgtggg gctctggagg tgggcagcaa 1050

 tctgtcaatc accttgttaa agagattgat atgctgctga aagaatattt 1100

 actctctgga gacatatctg aagctgaaca ttgccttaag gaactggaag 1150

 tacctcattt tcaccatgag cttgtatatg aagctattat aatggtttta 1200

 gagtcaactg gagaaagtac atttaagatg attttggatt tattaaagtc 1250

 cctttggaag tcttctacca ttactgtaga ccaaatgaaa agaggttatg 1300

 agagaattta caatgaaatt ccggacatta atctggatgt cccacattca 1350

 tactctgtgc tggagcggtt tgtagaagaa tgttttcagg ctggaataat 1400

 ttggaaacaa ctcagagatc tttgtccttc aaggggcaga aagcgttttg 1450

 taagcgaagg agatggaggt cgtcttaaac cagagagcta ctgaatataa 1500

 gaactcttgc agtcttagat gttataaaaa tatatatctg aattgtaaga 1550

 gttgttagca caagtttttt tttttttttt tttaagcact tgttttgggt 1600

 acaaggcatt tctgacattt tgggta 1626

<210> 5800
<211> 469
<212> PRT
<213> Homo sapien

<400> 5800
 Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp
   1               5                  10                  15

 Pro Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn
                  20                  25                  30

 Ala Gly Thr Glu Glu Val Lys Asn Glu Ile Asn Gly Asn Trp Ile
                  35                  40                  45

 Ser Ala Ser Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys
                  50                  55                  60

 Arg Arg Leu Arg Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp
                  65                  70                  75

 Ser Val Ser Asp Ser Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr
                  80                  85                  90

 Val Pro Thr Ser Pro Lys Gly Arg Leu Leu Asp Gly Arg Ser Arg
                  95                 100                 105

 Ser Gly Lys Gly Arg Gly Leu Pro Lys Lys Gly Gly Ala Gly Gly
                 110                 115                 120

 Lys Gly Val Trp Gly Thr Pro Gly Gln Gly Tyr Asp Val Glu Glu
                 125                 130                 135

 Val Asp Val Lys Asp Pro Asn Tyr Asp Asp Asp Gln Glu Asn Cys
                 140                 145                 150

 Val Tyr Glu Thr Val Val Leu Pro Leu Asp Glu Arg Ala Phe Glu
                 155                 160                 165

 Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe Glu His Gly Asp
                 170                 175                 180

 Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn Leu Gly Glu
                 185                 190                 195

 Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala Leu Glu
                 200                 205                 210

 Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Phe Leu Ser Asp
                 215                 220                 225

 Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe
                 230                 235                 240

 Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro
                 245                 250                 255

 Arg Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly
                 260                 265                 270

 Asp Gly Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr
                 275                 280                 285

 Val Asp Cys Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val
                 290                 295                 300

 Leu Leu Ser Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp
                 305                 310                 315

 Gly Ser Gly Gly Gly Gln Gln Ser Val Asn His Leu Val Lys Glu
                 320                 325                 330

 Ile Asp Met Leu Leu Lys Glu Tyr Leu Leu Ser Gly Asp Ile Ser
                 335                 340                 345

 Glu Ala Glu His Cys Leu Lys Glu Leu Glu Val Pro His Phe His
                 350                 355                 360

 His Glu Leu Val Tyr Glu Ala Ile Ile Met Val Leu Glu Ser Thr
                 365                 370                 375

 Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu Lys Ser Leu
                 380                 385                 390

 Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg Gly Tyr
                 395                 400                 405

 Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val Pro
                 410                 415                 420

 His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln
                 425                 430                 435

 Ala Gly Ile Ile Trp Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg
                 440                 445                 450

 Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys
                 455                 460                 465

 Pro Glu Ser Tyr


<210> 5801
<211> 5316
<212> DNA
<213> Homo sapien

<400> 5801
 cggacgcgtg ggaacgaagc cacccattac ggtatgatga tgtcaaacgt 50

 gatgctgatg ctacagttac agcccctgct ggcgcagcct ctctgattct 100

 ctctccctct ccgcgtccag tgctgggctt tttcagacaa gtgcatctcc 150

 taaccaggtc acatttcagc cgcgacccac tctccgccag tcaccggagg 200

 cagaccgcgg gaggagagct gaggacagcc gcgtgcgctt cgccagcagc 250

 ggggtgggag gaaggacatt aaaatactgc agaagtcaag accccccagg 300

 tcgaacccag accacgatgc gcgccccggg ctgcgggcgg ctggtgctgc 350

 cgctgctgct cctggccgcg gcagccctgg ccgaaggcga cgccaagggg 400

 ctcaaggagg gcgagacccc cggcaatttc atggaggacg agcaatggct 450

 gtcgtccatc tcgcagtaca gcggcaagat caagcactgg aaccgcttcc 500

 gagacgaagt ggaggatgac tatatcaaga gctgggagga caatcagcaa 550

 ggagatgaag ccctggatac caccaaggac ccctgccaga aggtgaagtg 600

 cagccgccac aaggtgtgca ttgcccaggg ctaccagcgg gccatgtgca 650

 tcagtcgcaa gaagctggag cacaggatca agcagccgac cgtgaaactc 700

 catggaaaca aagactccat ctgcaagccc tgccacatgg cccagcttgc 750

 ctctgtctgc ggctcagatg gccacactta cagctctgtg tgtaagctgg 800

 agcaacaggc gtgcctgagc agcaagcagc tggcggtgcg atgcgagggc 850

 ccctgcccct gccccacgga gcaggctgcc acctccaccg ccgatggcaa 900

 accagagact tgcaccggtc aggacctggc tgacctggga gatcggctgc 950

 gggactggtt ccagctcctt catgagaact ccaagcagaa tggctcagcc 1000

 agcagtgtag ccggcccggc cagcgggctg gacaagagcc tgggggccag 1050

 ctgcaaggac tccattggct ggatgttctc caagctggac accagtgctg 1100

 acctcttcct ggaccagacg gagctggccg ccatcaacct ggacaagtac 1150

 gaggtctgca tccgtccctt cttcaactcc tgtgacacct acaaggatgg 1200

 ccgggtctct actgctgagt ggtgcttctg cttctggagg gagaagcccc 1250

 cctgcctggc agagctggag cgcatccaga tccaggaggc cgccaagaag 1300

 aagccaggca tcttcatccc gagctgcgac gaggatggct actaccggaa 1350

 gatgcagtgt gaccagagca gcggtgactg ctggtgtgtg gaccagctgg 1400

 gcctggagct gactggcacg cgcacgcatg ggagccccga ctgcgatgac 1450

 atcgtgggct tctcggggga ctttggaagc ggtgtcggct gggaggatga 1500

 ggaggagaag gagacggagg aagcaggcga ggaggccgag gaggaggagg 1550

 gcgaggcagg cgaggctgac gacgggggct acatctggta gacgccctca 1600

 gaagccggct gccggggggg actcaacagc agagctctga gcagcagcag 1650

 gcaacttcga gaacggatcc agaaatgcag tcagaaggac cctgctccac 1700

 ctggggggac tgggagtgtg agtgtgcatg gcatgtgtgt ggcacagatg 1750

 gctgggacgg gtgacagtgt gagtgcatgt gtgcatgcat gtgtgtatgt 1800

 gtgtgtgtgt gtggcatgcg ctgacaaatg tgtccttgat ccacactgct 1850

 cctggcagag tgagtaaccc aaaggcccct tcggcctcct tgtagctgtt 1900

 ttctttcctt ttgttgttgg ttttaaaata cattcacaca caaatacaaa 1950

 ttgacaggtc aaaatccatg aaatgagatc ccccagccgt gtcctccagc 2000

 ccagccctga ccccttggtt tctaccctgg ctccccttgg tttctaccct 2050

 ggctcaaccg acccctgtct gcccttctcc ctcctgcttc tgaggtcaag 2100

 ctctggcctg cgagcctgtc cccattgcaa aggggaggga ggggcaggga 2150

 gctgtctacc agctgaggtc ctcccaaaac tgggccgatg tggtgtgaca 2200

 tccccaccag cctcagatga gacgggccag gacgcccagc cacagcaagc 2250

 cctgtccctt tgccggatcc ccaaacacta gagaagctct cctaacccaa 2300

 ggcggagaat gaaggtggtg gcggcagagg aggagggcag cagctgagag 2350

 gccagggaca gggtgcctcg ccaagctgtc tgaggtctgt cccaggtggc 2400

 ccaggtggtg caggtagaac agggtgagga gagggggtcg gctcaacagg 2450

 aggaggctgt ggctgcagag cctggaggag cttttaggtg ttgagatggg 2500

 gcagctctga atcctagacc ctggaatagc ctgtcccttt tctctgggtc 2550

 tcgtggtgga gccatgatct gggctgctct cttggggaca ctgggtggtg 2600

 gttacacagt tgacctctgc ctggctcccc cttggtgcaa ctcctgcctc 2650

 catccccctt gctggggtcc cctcatccac ttgagggcgc ctgagggcca 2700

 ggagcagcag gcaaggagcc tgggtctagg ctaagggggt gtgtgcccac 2750

 ctcctccctg acccttaaca ctcctgtcct gcccagacca acagagagag 2800

 ctgtccctga gaccccggag agaagcagct gccgaaagct gcagcctttc 2850

 cgcactctga gaccatgatc ttcctcctgc caggggagag ccacccacag 2900

 gccatgtcca gccccacttc cctcagcccc cagggcttcc ttctggcccc 2950

 tctgaggatt ccctagggct gccccgcaga ggggcttccc caagctctgt 3000

 tttgaagcct gcaatgtgga aaagtgagaa gtcagaggga acaggacagg 3050

 tgcagccggg ctctgaggcc acacctcaca cctcgctgtt ccccaacatc 3100

 ccctgagcag tgtgagctca tctcaccaga tgagaagagg ccctgtgcat 3150

 ttcttttgtt tgtttgttgc tgttttcccc cacccatcca gttctcctca 3200

 gcaaagcaaa ttccttaaca cctttggtgg agaatttctt acccagactt 3250

 ggggctgtga tgcccttcag tgcgtggtga gtgcagcgtg tgtgcgtgtg 3300

 cctgtgtgtg aacctggggg ccatcctggt ggcctgggag cgtgaggaga 3350

 ggccccctgt gtgctgggtg agtggtgggt gtggggtcaa tgcagtgagg 3400

 ctctctgggt gaggctccca acctggcagt ccccagcctc ccagcatctg 3450

 tgagcgtctg ttggacttta cagaagagcc tcatcccgtc tgcccctcac 3500

 tctgccctgg aatcaacatc ttccgagtcc ttcttggggg aaatagcaga 3550

 gccccactta actccataaa ctgcttccca ttccgcagcc cagttctgat 3600

 tgttgaggtg tcgcgtcgtt ccaggtcccc cagtcccctc tttctcctgt 3650

 cctctctctg tccttcacct ccccactcca gccccggctc agttcaggga 3700

 aatgctgttc catatcagcc ctctgctctc tgaggcagcc gcgcctctga 3750

 ctcggagcta cttgaaactt ctgctcttgc taggattgga gtctacctat 3800

 ctcttccatt tgtcccagct ggagttctgg aactttcctc ctcggggtgg 3850

 gggtgggggt tgttaaggat gctggggggc ctggggaagg aaggagttca 3900

 gaggaagggt gtcccctgtc ctcttgatgt caccctccgc tcctgggaca 3950

 cgtgctctct ctgtctctgg gtcttctggc tgtgcacgtt tgtgtgtcct 4000

 tgtaaatatg ttttaggaag aaagcaaaag ggactgaact agcctctggt 4050

 aggattgcag gggtccagcc ttgcctgttt ccgaagcccc cacactgcct 4100

 ttcgccccac tgagactggt cccctcaaaa ggtagacaaa acagcagctc 4150

 cctgtggagc tgaagggcgg cctcaaagtg gctttttgtt agacaaggtt 4200

 aaggtttcct catgagcaag gttgcagatc ggtccttcct cagctccttg 4250

 atttgtgacc ttgaccaagg ggcctgccac ccagcccctc cagtgccctc 4300

 tcctcgatgc ctcgctcctt cctgccccca ctcccctggc ttaggcaggt 4350

 aggggaatta gggccatgct ggaagaagct taaccatgtg ttcaaagaac 4400

 ggtttcttgc ttgcttggtc ctggaactcc ccttggctgc cccaggcctc 4450

 cttggcccat gggtgctggg ggaggtggat gtcagatctg gtaggttgca 4500

 gcagagaaaa taaatgtgcc ttgagagacc actcagagag ggtccaaggg 4550

 tgatggagaa ggaagcatgg cctgggagct tggaagggag gggtggtggg 4600

 tggcggcatc ttgactgccc cctgttgtcc cacacgtggg gggtggtcac 4650

 cccccttcac tccagcccgc ctgccttcag ccttccatga gcttcacctg 4700

 cttccaactt cactttggag ggggtggggt ccgttggcat caacacgggg 4750

 accctctgct tcaccaaagc ccgagccctc agcccctggg gagaacaaat 4800

 ggctgagctt tgatacctgg ggtcgtcgag aggctgcggg ctggcggcag 4850

 tcccagggga gagacaccac agaaggagac ccagacatcc cgaggaagtt 4900

 cccagcagag caaactgctt tccagcctga agcctgctta aactgtgtga 4950

 tgtgcaataa ctgagcttag agttaggaat tgtgttcaag tgcttggatt 5000

 tccgtctgta gatttaactg ctgaaattgt atctctcagt aattttagat 5050

 gtcttttaaa aaattgaaaa acaaagtgtt agactgtgtg cgtgtgcgtt 5100

 gatgggcact caagagtccc gtgagtcatc cagccctgcc tttcccctgc 5150

 gcccccatcc tctcacgtcc cgccctgcct ccacttgggg accctgcctc 5200

 gtgtcgtctt tatctgccta ttactcagcc taaggaaaca agtacactcc 5250

 acacatgcat aaaggaaatc aaatgttatt tttaagaaaa tggaaaataa 5300

 aaactttata aacacc 5316

<210> 5802
<211> 424
<212> PRT
<213> Homo sapien

<400> 5802
 Met Arg Ala Pro Gly Cys Gly Arg Leu Val Leu Pro Leu Leu Leu
   1               5                  10                  15

 Leu Ala Ala Ala Ala Leu Ala Glu Gly Asp Ala Lys Gly Leu Lys
                  20                  25                  30

 Glu Gly Glu Thr Pro Gly Asn Phe Met Glu Asp Glu Gln Trp Leu
                  35                  40                  45

 Ser Ser Ile Ser Gln Tyr Ser Gly Lys Ile Lys His Trp Asn Arg
                  50                  55                  60

 Phe Arg Asp Glu Val Glu Asp Asp Tyr Ile Lys Ser Trp Glu Asp
                  65                  70                  75

 Asn Gln Gln Gly Asp Glu Ala Leu Asp Thr Thr Lys Asp Pro Cys
                  80                  85                  90

 Gln Lys Val Lys Cys Ser Arg His Lys Val Cys Ile Ala Gln Gly
                  95                 100                 105

 Tyr Gln Arg Ala Met Cys Ile Ser Arg Lys Lys Leu Glu His Arg
                 110                 115                 120

 Ile Lys Gln Pro Thr Val Lys Leu His Gly Asn Lys Asp Ser Ile
                 125                 130                 135

 Cys Lys Pro Cys His Met Ala Gln Leu Ala Ser Val Cys Gly Ser
                 140                 145                 150

 Asp Gly His Thr Tyr Ser Ser Val Cys Lys Leu Glu Gln Gln Ala
                 155                 160                 165

 Cys Leu Ser Ser Lys Gln Leu Ala Val Arg Cys Glu Gly Pro Cys
                 170                 175                 180

 Pro Cys Pro Thr Glu Gln Ala Ala Thr Ser Thr Ala Asp Gly Lys
                 185                 190                 195

 Pro Glu Thr Cys Thr Gly Gln Asp Leu Ala Asp Leu Gly Asp Arg
                 200                 205                 210

 Leu Arg Asp Trp Phe Gln Leu Leu His Glu Asn Ser Lys Gln Asn
                 215                 220                 225

 Gly Ser Ala Ser Ser Val Ala Gly Pro Ala Ser Gly Leu Asp Lys
                 230                 235                 240

 Ser Leu Gly Ala Ser Cys Lys Asp Ser Ile Gly Trp Met Phe Ser
                 245                 250                 255

 Lys Leu Asp Thr Ser Ala Asp Leu Phe Leu Asp Gln Thr Glu Leu
                 260                 265                 270

 Ala Ala Ile Asn Leu Asp Lys Tyr Glu Val Cys Ile Arg Pro Phe
                 275                 280                 285

 Phe Asn Ser Cys Asp Thr Tyr Lys Asp Gly Arg Val Ser Thr Ala
                 290                 295                 300

 Glu Trp Cys Phe Cys Phe Trp Arg Glu Lys Pro Pro Cys Leu Ala
                 305                 310                 315

 Glu Leu Glu Arg Ile Gln Ile Gln Glu Ala Ala Lys Lys Lys Pro
                 320                 325                 330

 Gly Ile Phe Ile Pro Ser Cys Asp Glu Asp Gly Tyr Tyr Arg Lys
                 335                 340                 345

 Met Gln Cys Asp Gln Ser Ser Gly Asp Cys Trp Cys Val Asp Gln
                 350                 355                 360

 Leu Gly Leu Glu Leu Thr Gly Thr Arg Thr His Gly Ser Pro Asp
                 365                 370                 375

 Cys Asp Asp Ile Val Gly Phe Ser Gly Asp Phe Gly Ser Gly Val
                 380                 385                 390

 Gly Trp Glu Asp Glu Glu Glu Lys Glu Thr Glu Glu Ala Gly Glu
                 395                 400                 405

 Glu Ala Glu Glu Glu Glu Gly Glu Ala Gly Glu Ala Asp Asp Gly
                 410                 415                 420

 Gly Tyr Ile Trp


<210> 5803
<211> 5523
<212> DNA
<213> Homo sapien

<400> 5803
 ggcgatcacg ttttcacatg atgctcacgc tcagggcgct tcaattatcc 50

 ctccccacaa agataggtgg cgcgtgtttc agggtctctc gtctctctcc 100

 tacagaaaag aaaaagaaaa aaatgtcatt agaagaggcg taacacgtca 150

 gtccgtcccc aggtttgtgt ttcctggagt ggccgaaaga gatcagttct 200

 aacctgctct gcaggaataa cggtcctgcc tcccgacact cttggcgagg 250

 tttttgtaca gtttgctccg ggagctgttt cttcgcttcc acctttttct 300

 cccccacact tcgcggcttc ttcatgcttt ttcttctcac catttctggc 350

 caaaactaca aacaagactt cgcagatcga gcctgcgtgc tgccgaagca 400

 gggcgccgag tccatgcgaa ctgccatctg atccgctctt atcaatgaag 450

 cagccgatca tggcggatgg cccccggtgc aagaggcgca aacaagccaa 500

 tcccaggagg aaaaacgtgg tgaactatga caatgtagtg gacacaggtt 550

 ctgaaacaga tgaggaagac aagcttcata ttgctgagga tgacggtatt 600

 gccaaccctc tggaccagga gacgagtcca gctagtgtgc ccaaccatga 650

 gtcctcccca cacgtgagcc aagctctgtt gccaagagag gaagaggaag 700

 atgaaataag ggagggtgga gtggaacacc cctggcacaa caacgagatt 750

 ctacaagcct ctgtagatgg tccagaagaa atgaaggaag actatgacac 800

 tatggggcca gaagccacga tccagaccgc aattaacaat ggtacagtga 850

 agaatgcaaa ttgcacatca gattttgagg aatactttgc caaaagaaaa 900

 ctggaggaac gcgatggtca tgcagtcagc atcgaggagt accttcagcg 950

 cagtgacaca gccattattt acccagaagc ccctgaggag ctgtctcgcc 1000

 ttggcacgcc agaggccaat gggcaagaag aaaatgacct gccacctgga 1050

 actccagatg cttttgccca actgctgacc tgcccctact gcgaccgggg 1100

 ctacaagcgc ttgacatcac tgaaggagca catcaagtac cgccacgaga 1150

 agaatgaaga gaacttttcc tgccctctct gtagctacac gtttgcctac 1200

 cgcacccagc tcgagcggca tatggtgaca cacaagccag ggacagatca 1250

 gcaccaaatg ctaacccaag gagcaggtaa tcgcaagttc aaatgcacag 1300

 agtgtggcaa ggccttcaaa tataaacacc atctgaaaga acacctgcga 1350

 attcacagtg gtgaaaaacc ttacgagtgc ccaaactgca agaaacgttt 1400

 ctcccattct ggttcctaca gttcgcacat cagcagcaag aaatgtattg 1450

 gtttaatctc tgtaaatggc cgaatgagaa acaatatcaa gacgggttct 1500

 tcccctaatt ctgtttcttc ttctcctact aattcagcca ttacccagtt 1550

 aagaaacaag ttggagaatg gaaaaccact tagtatgtct gaacagacag 1600

 gcttacttaa aattaaaaca gaaccactag acttcaatga ctataaagtt 1650

 cttatggcta cacacgggtt tagtggcact agtcccttta tgaatggtgg 1700

 gcttggagcc accagccctt taggagttca tccatctgct cagagtccaa 1750

 tgcagcactt aggtgtaggg atggaagccc ctttacttgg gtttcccacc 1800

 atgaatagta atttaagtga ggtacaaaag gttctacaga ttgtggacaa 1850

 tactgtttcc aggcaaaaaa tggactgcaa ggctgaagaa atttcaaagt 1900

 tgaaaggtta tcacatgaag gatccatgct ctcaacctga ggaacaagga 1950

 gttacttctc ctaatattcc gcctgtcggt cttccggtag tgagtcataa 2000

 tggtgccact aaaagtatta ttgactatac gttggaaaaa gtcaatgaag 2050

 ccaaagcttg cctccagagc ttgactactg actcaaggag acagatcagt 2100

 aatataaaga aagagaagct acgtacttta atagatttgg tcactgatga 2150

 caaaatgatt gagaaccaca acatatccac tccattttca tgccagttct 2200

 gtaaagaaag ttttcctggc cccatccctt tgcatcagca tgaacgttac 2250

 ctttgtaaga tgaatgaaga gatcaaggcg gtcctgcagc ctcatgaaaa 2300

 catagtcccc aacaaagccg gagtttttgt tgataataaa gccctcctct 2350

 tgtcatctgt actttctgag aaaggaatga caagccccat caacccatac 2400

 aaggaccaca tgtctgtact caaagcatac tatgctatga acatggagcc 2450

 caactccgat gaactgctga aaatttccat tgctgtgggc cttcctcagg 2500

 aatttgtgaa ggaatggttt gaacaacgaa aagtctacca gtactcaaat 2550

 tccaggtccc catccctgga aagaagctcc aagccgttag ctcccaacag 2600

 taaccctccc acaaaagact ctttattacc caggtctcct gtaaaaccta 2650

 tggactccat aacatcacca tctatagcag aactccacaa cagtgttacg 2700

 aattgtgatc ctcctctcag gctaacaaaa ccttcccatt ttaccaatat 2750

 taaaccagtt gaaaaattgg accactccag gagtaatact ccttctccct 2800

 taaatctttc ctccacatct tctaaaaact cccacagtag ttcatacact 2850

 ccaaacagct tctcttctga ggagctccag gctgagcctt tagacttgtc 2900

 attaccaaaa caaatgaaag aacccaaaag tattatagcc acaaagaaca 2950

 aaacaaaagc tagtagcatc agtttagatc ataacagtgt ttcttcctca 3000

 tctgaaaact cagatgagcc tctgaacttg acttttatca agaaggaatt 3050

 ttcaaattca aataatctgg acaacaaaag cactaaccca gtgttcagca 3100

 tgaacccatt tagtgccaaa cctttataca cagctcttcc acctcaaagc 3150

 gcatttcccc ctgctacttt catgccacca gtccagacca gtattcctgg 3200

 gctacgacca tacccaggac tggatcagat gagcttccta ccacatatgg 3250

 cctacaccta cccaactgga gcagctactt ttgctgatat gcagcaaagg 3300

 agaaagtacc agcggaaaca aggatttcag ggagaattgc ttgatggagc 3350

 acaagactac atgtcaggcc tagatgatat gacagactcc gactcctgtc 3400

 tgtctcgcaa aaagatcaag aagacagaga gtggcatgta tgcatgtgac 3450

 ttatgtgaca agacattcca gaaaagcagt tcccttctgc gacataaata 3500

 cgaacacaca ggaaaaagac cacatcagtg tcagatttgt aagaaagcgt 3550

 ttaaacacaa gcaccacctt atcgagcact caaggcttca ctcgggcgag 3600

 aagccctatc agtgtgataa atgtggcaag cgcttctcac actcgggctc 3650

 gtactcgcag cacatgaatc acaggtattc ctactgcaag cgggaggcgg 3700

 aggagcggga agcggcggag cgcgaggcgc gcgagaaagg gcacttggaa 3750

 cccaccgagc tgctgatgaa ccgggcttac ttgcagagca ttacccctca 3800

 ggggtactct gactcggagg agagggagag tatgccgagg gatggcgaga 3850

 gcgagaagga gcacgagaaa gaaggcgagg atggctacgg gaagctgggc 3900

 agacaggatg gcgacgagga gttcgaggag gaagaggaag aaagtgaaaa 3950

 taaaagtatg gatacggatc ccgaaacgat acgagatgaa gaagagactg 4000

 gagatcactc catggacgat agttcggagg atgggaaaat ggaaaccaaa 4050

 tcagaccacg aggaagacaa tatggaagat ggcatgtaat aaactactgc 4100

 attttaagct tcctattttt ttttccagta gtattgttac ctgcttgaaa 4150

 acactgctgt gttaagctgt tcatgcacgt gcctgacgct tccaggaagc 4200

 tgtagagagg gacagaaggg gcggttcagc caagacagat gtagacggag 4250

 ttggagctgg gtattgttaa aaactgcatt atgcaaaaat tttgtacagt 4300

 gttaaggcct aaaaactgtg tggttcagag actaattcct gtgtttaata 4350

 gcatttatac tttaagcaca actagaaaat tgtaagaatt gcactctact 4400

 tatgtatcac tacaaacttt aaaaaactat gtctaattta tattaataca 4450

 ttttaaaaag gtgcccgcac taccatacat cagtattttt attattatta 4500

 ttgttattcc tttttaattt aatgtgctcg cactacaatg catcagtatt 4550

 atgattcctc tgtactttcc tttcgctatt catcaatttc ccattttttt 4600

 ttttcagctt aagtaaccac acaattttag gcctcaattt tttttttttt 4650

 ctgtgaagga acttgaagtg atgcatgtgt gaatttaaga taccgaagtc 4700

 ttaaagtgac ctggacgtga aggaaaaagt aagatgagaa ataaagaaag 4750

 cctttgtaag gtggttttaa aagccttata tgcaaacctt ttaatctgtg 4800

 tttctgcaag tgccatcctt gtacagtgtt aagagggtaa catgggttac 4850

 ctttgcacca gcttcagtgt taagctcacc ctgttctttg aagcacccat 4900

 gtcagtatta gaagaatagg cagcagttcc ttagtttaca tatgtttgtg 4950

 caattatttt ctgtactttt ttgttcatta attttgtcag tattacacca 5000

 aactgttttt gcaacaaaaa aatttttttt gcattcattt aattttaggt 5050

 caaataacat tttatttatg tggctcattt tatatttcct aattttattt 5100

 atttcatact gtagtgtaca gtattatagt tcttcaatat atagatatat 5150

 tttagtaaaa aaggaacatg acgttgatca tttgggcaaa ttttacgtaa 5200

 agagaagagc atttattgtg ttttggaaca ttaattgtga gatgggattt 5250

 ttcaatttta ttattttatt tttgtttttt tccaattact ggaaattcca 5300

 aatttgggaa cttttgatac gatcttgtga aaacactgta ttttcgactg 5350

 aaaattccac tttcttcatc ttgtttttta gctaaaaaga gggactgtta 5400

 aatacaatgt atgataccat gacaaaaatc tttcctgaat tgtctttgta 5450

 aaagtattat tgaattttca atttgtaatt tcttttgaaa atgaccatgc 5500

 tcgaataaaa atgtagccaa act 5523

<210> 5804
<211> 1214
<212> PRT
<213> Homo sapien

<400> 5804
 Met Lys Gln Pro Ile Met Ala Asp Gly Pro Arg Cys Lys Arg Arg
   1               5                  10                  15

 Lys Gln Ala Asn Pro Arg Arg Lys Asn Val Val Asn Tyr Asp Asn
                  20                  25                  30

 Val Val Asp Thr Gly Ser Glu Thr Asp Glu Glu Asp Lys Leu His
                  35                  40                  45

 Ile Ala Glu Asp Asp Gly Ile Ala Asn Pro Leu Asp Gln Glu Thr
                  50                  55                  60

 Ser Pro Ala Ser Val Pro Asn His Glu Ser Ser Pro His Val Ser
                  65                  70                  75

 Gln Ala Leu Leu Pro Arg Glu Glu Glu Glu Asp Glu Ile Arg Glu
                  80                  85                  90

 Gly Gly Val Glu His Pro Trp His Asn Asn Glu Ile Leu Gln Ala
                  95                 100                 105

 Ser Val Asp Gly Pro Glu Glu Met Lys Glu Asp Tyr Asp Thr Met
                 110                 115                 120

 Gly Pro Glu Ala Thr Ile Gln Thr Ala Ile Asn Asn Gly Thr Val
                 125                 130                 135

 Lys Asn Ala Asn Cys Thr Ser Asp Phe Glu Glu Tyr Phe Ala Lys
                 140                 145                 150

 Arg Lys Leu Glu Glu Arg Asp Gly His Ala Val Ser Ile Glu Glu
                 155                 160                 165

 Tyr Leu Gln Arg Ser Asp Thr Ala Ile Ile Tyr Pro Glu Ala Pro
                 170                 175                 180

 Glu Glu Leu Ser Arg Leu Gly Thr Pro Glu Ala Asn Gly Gln Glu
                 185                 190                 195

 Glu Asn Asp Leu Pro Pro Gly Thr Pro Asp Ala Phe Ala Gln Leu
                 200                 205                 210

 Leu Thr Cys Pro Tyr Cys Asp Arg Gly Tyr Lys Arg Leu Thr Ser
                 215                 220                 225

 Leu Lys Glu His Ile Lys Tyr Arg His Glu Lys Asn Glu Glu Asn
                 230                 235                 240

 Phe Ser Cys Pro Leu Cys Ser Tyr Thr Phe Ala Tyr Arg Thr Gln
                 245                 250                 255

 Leu Glu Arg His Met Val Thr His Lys Pro Gly Thr Asp Gln His
                 260                 265                 270

 Gln Met Leu Thr Gln Gly Ala Gly Asn Arg Lys Phe Lys Cys Thr
                 275                 280                 285

 Glu Cys Gly Lys Ala Phe Lys Tyr Lys His His Leu Lys Glu His
                 290                 295                 300

 Leu Arg Ile His Ser Gly Glu Lys Pro Tyr Glu Cys Pro Asn Cys
                 305                 310                 315

 Lys Lys Arg Phe Ser His Ser Gly Ser Tyr Ser Ser His Ile Ser
                 320                 325                 330

 Ser Lys Lys Cys Ile Gly Leu Ile Ser Val Asn Gly Arg Met Arg
                 335                 340                 345

 Asn Asn Ile Lys Thr Gly Ser Ser Pro Asn Ser Val Ser Ser Ser
                 350                 355                 360

 Pro Thr Asn Ser Ala Ile Thr Gln Leu Arg Asn Lys Leu Glu Asn
                 365                 370                 375

 Gly Lys Pro Leu Ser Met Ser Glu Gln Thr Gly Leu Leu Lys Ile
                 380                 385                 390

 Lys Thr Glu Pro Leu Asp Phe Asn Asp Tyr Lys Val Leu Met Ala
                 395                 400                 405

 Thr His Gly Phe Ser Gly Thr Ser Pro Phe Met Asn Gly Gly Leu
                 410                 415                 420

 Gly Ala Thr Ser Pro Leu Gly Val His Pro Ser Ala Gln Ser Pro
                 425                 430                 435

 Met Gln His Leu Gly Val Gly Met Glu Ala Pro Leu Leu Gly Phe
                 440                 445                 450

 Pro Thr Met Asn Ser Asn Leu Ser Glu Val Gln Lys Val Leu Gln
                 455                 460                 465

 Ile Val Asp Asn Thr Val Ser Arg Gln Lys Met Asp Cys Lys Ala
                 470                 475                 480

 Glu Glu Ile Ser Lys Leu Lys Gly Tyr His Met Lys Asp Pro Cys
                 485                 490                 495

 Ser Gln Pro Glu Glu Gln Gly Val Thr Ser Pro Asn Ile Pro Pro
                 500                 505                 510

 Val Gly Leu Pro Val Val Ser His Asn Gly Ala Thr Lys Ser Ile
                 515                 520                 525

 Ile Asp Tyr Thr Leu Glu Lys Val Asn Glu Ala Lys Ala Cys Leu
                 530                 535                 540

 Gln Ser Leu Thr Thr Asp Ser Arg Arg Gln Ile Ser Asn Ile Lys
                 545                 550                 555

 Lys Glu Lys Leu Arg Thr Leu Ile Asp Leu Val Thr Asp Asp Lys
                 560                 565                 570

 Met Ile Glu Asn His Asn Ile Ser Thr Pro Phe Ser Cys Gln Phe
                 575                 580                 585

 Cys Lys Glu Ser Phe Pro Gly Pro Ile Pro Leu His Gln His Glu
                 590                 595                 600

 Arg Tyr Leu Cys Lys Met Asn Glu Glu Ile Lys Ala Val Leu Gln
                 605                 610                 615

 Pro His Glu Asn Ile Val Pro Asn Lys Ala Gly Val Phe Val Asp
                 620                 625                 630

 Asn Lys Ala Leu Leu Leu Ser Ser Val Leu Ser Glu Lys Gly Met
                 635                 640                 645

 Thr Ser Pro Ile Asn Pro Tyr Lys Asp His Met Ser Val Leu Lys
                 650                 655                 660

 Ala Tyr Tyr Ala Met Asn Met Glu Pro Asn Ser Asp Glu Leu Leu
                 665                 670                 675

 Lys Ile Ser Ile Ala Val Gly Leu Pro Gln Glu Phe Val Lys Glu
                 680                 685                 690

 Trp Phe Glu Gln Arg Lys Val Tyr Gln Tyr Ser Asn Ser Arg Ser
                 695                 700                 705

 Pro Ser Leu Glu Arg Ser Ser Lys Pro Leu Ala Pro Asn Ser Asn
                 710                 715                 720

 Pro Pro Thr Lys Asp Ser Leu Leu Pro Arg Ser Pro Val Lys Pro
                 725                 730                 735

 Met Asp Ser Ile Thr Ser Pro Ser Ile Ala Glu Leu His Asn Ser
                 740                 745                 750

 Val Thr Asn Cys Asp Pro Pro Leu Arg Leu Thr Lys Pro Ser His
                 755                 760                 765

 Phe Thr Asn Ile Lys Pro Val Glu Lys Leu Asp His Ser Arg Ser
                 770                 775                 780

 Asn Thr Pro Ser Pro Leu Asn Leu Ser Ser Thr Ser Ser Lys Asn
                 785                 790                 795

 Ser His Ser Ser Ser Tyr Thr Pro Asn Ser Phe Ser Ser Glu Glu
                 800                 805                 810

 Leu Gln Ala Glu Pro Leu Asp Leu Ser Leu Pro Lys Gln Met Lys
                 815                 820                 825

 Glu Pro Lys Ser Ile Ile Ala Thr Lys Asn Lys Thr Lys Ala Ser
                 830                 835                 840

 Ser Ile Ser Leu Asp His Asn Ser Val Ser Ser Ser Ser Glu Asn
                 845                 850                 855

 Ser Asp Glu Pro Leu Asn Leu Thr Phe Ile Lys Lys Glu Phe Ser
                 860                 865                 870

 Asn Ser Asn Asn Leu Asp Asn Lys Ser Thr Asn Pro Val Phe Ser
                 875                 880                 885

 Met Asn Pro Phe Ser Ala Lys Pro Leu Tyr Thr Ala Leu Pro Pro
                 890                 895                 900

 Gln Ser Ala Phe Pro Pro Ala Thr Phe Met Pro Pro Val Gln Thr
                 905                 910                 915

 Ser Ile Pro Gly Leu Arg Pro Tyr Pro Gly Leu Asp Gln Met Ser
                 920                 925                 930

 Phe Leu Pro His Met Ala Tyr Thr Tyr Pro Thr Gly Ala Ala Thr
                 935                 940                 945

 Phe Ala Asp Met Gln Gln Arg Arg Lys Tyr Gln Arg Lys Gln Gly
                 950                 955                 960

 Phe Gln Gly Glu Leu Leu Asp Gly Ala Gln Asp Tyr Met Ser Gly
                 965                 970                 975

 Leu Asp Asp Met Thr Asp Ser Asp Ser Cys Leu Ser Arg Lys Lys
                 980                 985                 990

 Ile Lys Lys Thr Glu Ser Gly Met Tyr Ala Cys Asp Leu Cys Asp
                 995                1000                1005

 Lys Thr Phe Gln Lys Ser Ser Ser Leu Leu Arg His Lys Tyr Glu
                1010                1015                1020

 His Thr Gly Lys Arg Pro His Gln Cys Gln Ile Cys Lys Lys Ala
                1025                1030                1035

 Phe Lys His Lys His His Leu Ile Glu His Ser Arg Leu His Ser
                1040                1045                1050

 Gly Glu Lys Pro Tyr Gln Cys Asp Lys Cys Gly Lys Arg Phe Ser
                1055                1060                1065

 His Ser Gly Ser Tyr Ser Gln His Met Asn His Arg Tyr Ser Tyr
                1070                1075                1080

 Cys Lys Arg Glu Ala Glu Glu Arg Glu Ala Ala Glu Arg Glu Ala
                1085                1090                1095

 Arg Glu Lys Gly His Leu Glu Pro Thr Glu Leu Leu Met Asn Arg
                1100                1105                1110

 Ala Tyr Leu Gln Ser Ile Thr Pro Gln Gly Tyr Ser Asp Ser Glu
                1115                1120                1125

 Glu Arg Glu Ser Met Pro Arg Asp Gly Glu Ser Glu Lys Glu His
                1130                1135                1140

 Glu Lys Glu Gly Glu Asp Gly Tyr Gly Lys Leu Gly Arg Gln Asp
                1145                1150                1155

 Gly Asp Glu Glu Phe Glu Glu Glu Glu Glu Glu Ser Glu Asn Lys
                1160                1165                1170

 Ser Met Asp Thr Asp Pro Glu Thr Ile Arg Asp Glu Glu Glu Thr
                1175                1180                1185

 Gly Asp His Ser Met Asp Asp Ser Ser Glu Asp Gly Lys Met Glu
                1190                1195                1200

 Thr Lys Ser Asp His Glu Glu Asp Asn Met Glu Asp Gly Met
                1205                1210

<210> 5805
<211> 3988
<212> DNA
<213> Homo sapien

<400> 5805
 tgcaactccg agcgtgagtc caggctaagg ggacgccggc cggggaagag 50

 gcgcggcggg agaagcgacc gcagcgggag cccggccacc gagggctgcc 100

 ggcactaggc gcagagccgc cagcgctcgg aagcccgcgg ggtgcgggag 150

 cgggaacaga cttcttttgt agaattatcc tatggaatga tattttcata 200

 atgagtcaac aaggttacgt ggctacacct ccgtattctc agcctcagcc 250

 tggaataggc ctttctccac ctcattatgg gcactatggg gatccgtcgc 300

 acacagcatc tccaacaggt atgatgaagc cagcagggcc tttgggggcc 350

 accgccacta ggggaatgtt gcctccgggt cccccacctc ctggacccca 400

 tcagtttggt cagaatggag ctcatgccac tggtcaccct ccccaaagat 450

 ttccaggccc tccacctgtc aacaatgtgg catcctcaca tgcaccatac 500

 caaccctctg cacaatcttc ttatccaggt cctatatcca cttcatctgt 550

 cacccagctg ggcagccagc tcagtgctat gcaaatcaac agctatggtt 600

 caggcatggc tcctccaagc cagggacccc ctggccctct gtcagccaca 650

 tcattgcaga ctcctccacg acctccacag ccttccattt tgcagcctgg 700

 atctcaagtt cttccaccac cacccaccac actcaatggt cctggtgcct 750

 cacctttgcc tctaccaatg tacagaccag atgggctctc tgggcctcct 800

 cctccaaatg cccagtacca gcccccacct cttccaggcc agaccttggg 850

 tgctggatat cctccgcagc aggccaactc tggtccccag atggcaggcg 900

 cacaactgtc ttacccagga ggcttccctg gaggtcctgc acagatggct 950

 ggtccgccac agccccagaa gaagctggat cctgactcta tccctagccc 1000

 aatccaggtg attgagaatg atagagccag cagaggagga caagtttatg 1050

 ccaccaacac cagaggccag atccctcccc tggtcactac agattgcatg 1100

 atacaagacc aaggaaatgc cagtcctcga ttcatccgtt gtacaacata 1150

 ctgttttcca tgcacgtcag atatggctaa gcaagctcag attccattag 1200

 ctgctgtcat caagcccttt gccaccattc cttcaaatga gagtcccctt 1250

 tacttggtaa atcacggcga gagtggacca gtcagatgca acaggtgcaa 1300

 ggcctacatg tgcccattta tgcagttcat cgaaggagga aggagatatc 1350

 agtgtggatt ttgcaactgt gtgaatgatg ttccaccatt ctatttccaa 1400

 catctggacc acattggaag aagactggac cactatgaga aaccagagtt 1450

 atctctagga tcttatgaat atgttgccac tttggattat tgcagaaaga 1500

 gtaagcctcc caacccacca gcctttatct tcatgattga tgtttcatat 1550

 agtaacataa agaatggact tgtcaagctc atatgtgaag aactgaagac 1600

 catgctggaa aaaattccaa aggaagagca agaagagacg tctgcaattc 1650

 gagtgggttt tatcacatat aacaaagttc tccatttctt taatgtgaag 1700

 agtaatctgg cccagcctca gatgatggtg gtgactgatg ttggagaagt 1750

 ctttgttcct ttgttggatg gtttccttgt caactatcaa gaatcccaat 1800

 ctgtgattca taatttgttg gaccagattc cagacatgtt tgcagactct 1850

 aatgaaaatg agactgtctt tgcttctgtc atccaggctg gcatggaagc 1900

 actaaaggca gcagactgtc ctgggaagct gttcatcttc cattcttcct 1950

 tgccaactgc tgaagcacca gggaagctca aaaacagaga tgacaaaaaa 2000

 ctggttaata cagacaaaga gaagatactt ttccagcccc aaacaaatgt 2050

 ctatgactca ttggccaagg actgcgtggc tcacggctgc tctgtgacac 2100

 tcttcctctt tcctagtcag tatgtggacg tggcctcgct ggggctggtt 2150

 cctcagctca ctggaggaac cctttacaaa tacaacaatt tccagatgca 2200

 cttggataga caacaatttt tgaacgacct cagaaatgat attgaaaaga 2250

 aaataggctt tgatgctatt atgagggttc gtaccagcac aggtttcaga 2300

 gccactgatt tctttggtgg aatcttgatg aacaacacca ccgatgtaga 2350

 aatggctgcc atcgattgtg acaaggcagt gaccgtggag ttcaagcacg 2400

 atgacaaact cagtgaagac agtggagcct taatccagtg tgctgtgctt 2450

 tacacgacaa tcagtggtca aagaagactt cggattcaca atcttggctt 2500

 aaactgcagc tctcagctag ctgatcttta taagagctgt gagacagatg 2550

 ctcttatcaa cttctttgcc aagtcagctt ttaaagcagt tctccaccag 2600

 cctttgaagg tcatccggga aattctagtt aatcagactg cccatatgtt 2650

 ggcatgttac cggaagaatt gtgcaagtcc ttctgcagca agccagctta 2700

 ttctaccaga ttccatgaaa gtattgccag tgtacatgaa ttgcttgttg 2750

 aaaaactgtg tactactcag cagaccagag atctcaactg atgaacgagc 2800

 ataccagaga cagctggtca tgaccatggg tgtggctgac tctcagcttt 2850

 tcttctaccc acaacttctg cccatacaca cgttagatgt caagagtaca 2900

 atgttacctg ctgccgttcg ttgctctgag tcccgtcttt cagaagaagg 2950

 aatattctta ctggctaatg gtctacacat gttcctgtgg ttgggagtaa 3000

 gcagcccacc agaactgatc caaggaatat ttaatgtgcc atcttttgca 3050

 catatcaaca cagatatgac attgctgcct gaagtgggaa acccatactc 3100

 tcaacaactc agaatgataa tgggtattat ccaacaaaag aggccatatt 3150

 caatgaagct cacaattgta aagcagcgag aacaaccaga aatggttttc 3200

 cgacagttcc tggtagaaga caaaggactt tacggaggct cttcttatgt 3250

 ggatttcctt tgttgtgttc acaaggagat ctgtcagctg cttaattaat 3300

 tgaaacttct ctgtcattga tgttgcattt ccaaggagat aatctccttc 3350

 ttggtgccta attttctaga tgataatagg ctagttttga tttcttgctc 3400

 attttcagaa taactttcca ggaagagatg gcatttagaa cttcagcttt 3450

 ggtgctcagg tataaagcca attaaggtac aattgtacca taaagggaac 3500

 aatctgtttc tgattgcaca gtttctaatt tttaaaactg atgtggtttg 3550

 catttcataa aaggcaaagt ttacagaacc ataaacattc tcaattttct 3600

 ttatgctaga catataaatt atttttcaaa ctgtatagat ttggggtaaa 3650

 aagttgtctc agttcctctc ccaattgcaa tgagaaaaaa aagcttaatt 3700

 tttacattat acttaatttt ctaaaaccat gtaactccat tgaacatttt 3750

 tcaacttaag gtctgcatag cagactttta ataaccttgg gatttatctg 3800

 gtagaacaat atgtgttcta catttttttc ataattatat attgtgtatg 3850

 ttaaaactat tttccagttg ttttgtctgt aaaactgtct ttatcaatat 3900

 gcttaatggt tctttgtaca attttgaaag tttctacctg tatataatgg 3950

 atgttaacca gtatcaataa atcacttcgt ataatctt 3988

<210> 5806
<211> 1032
<212> PRT
<213> Homo sapien

<400> 5806
 Met Ser Gln Gln Gly Tyr Val Ala Thr Pro Pro Tyr Ser Gln Pro
   1               5                  10                  15

 Gln Pro Gly Ile Gly Leu Ser Pro Pro His Tyr Gly His Tyr Gly
                  20                  25                  30

 Asp Pro Ser His Thr Ala Ser Pro Thr Gly Met Met Lys Pro Ala
                  35                  40                  45

 Gly Pro Leu Gly Ala Thr Ala Thr Arg Gly Met Leu Pro Pro Gly
                  50                  55                  60

 Pro Pro Pro Pro Gly Pro His Gln Phe Gly Gln Asn Gly Ala His
                  65                  70                  75

 Ala Thr Gly His Pro Pro Gln Arg Phe Pro Gly Pro Pro Pro Val
                  80                  85                  90

 Asn Asn Val Ala Ser Ser His Ala Pro Tyr Gln Pro Ser Ala Gln
                  95                 100                 105

 Ser Ser Tyr Pro Gly Pro Ile Ser Thr Ser Ser Val Thr Gln Leu
                 110                 115                 120

 Gly Ser Gln Leu Ser Ala Met Gln Ile Asn Ser Tyr Gly Ser Gly
                 125                 130                 135

 Met Ala Pro Pro Ser Gln Gly Pro Pro Gly Pro Leu Ser Ala Thr
                 140                 145                 150

 Ser Leu Gln Thr Pro Pro Arg Pro Pro Gln Pro Ser Ile Leu Gln
                 155                 160                 165

 Pro Gly Ser Gln Val Leu Pro Pro Pro Pro Thr Thr Leu Asn Gly
                 170                 175                 180

 Pro Gly Ala Ser Pro Leu Pro Leu Pro Met Tyr Arg Pro Asp Gly
                 185                 190                 195

 Leu Ser Gly Pro Pro Pro Pro Asn Ala Gln Tyr Gln Pro Pro Pro
                 200                 205                 210

 Leu Pro Gly Gln Thr Leu Gly Ala Gly Tyr Pro Pro Gln Gln Ala
                 215                 220                 225

 Asn Ser Gly Pro Gln Met Ala Gly Ala Gln Leu Ser Tyr Pro Gly
                 230                 235                 240

 Gly Phe Pro Gly Gly Pro Ala Gln Met Ala Gly Pro Pro Gln Pro
                 245                 250                 255

 Gln Lys Lys Leu Asp Pro Asp Ser Ile Pro Ser Pro Ile Gln Val
                 260                 265                 270

 Ile Glu Asn Asp Arg Ala Ser Arg Gly Gly Gln Val Tyr Ala Thr
                 275                 280                 285

 Asn Thr Arg Gly Gln Ile Pro Pro Leu Val Thr Thr Asp Cys Met
                 290                 295                 300

 Ile Gln Asp Gln Gly Asn Ala Ser Pro Arg Phe Ile Arg Cys Thr
                 305                 310                 315

 Thr Tyr Cys Phe Pro Cys Thr Ser Asp Met Ala Lys Gln Ala Gln
                 320                 325                 330

 Ile Pro Leu Ala Ala Val Ile Lys Pro Phe Ala Thr Ile Pro Ser
                 335                 340                 345

 Asn Glu Ser Pro Leu Tyr Leu Val Asn His Gly Glu Ser Gly Pro
                 350                 355                 360

 Val Arg Cys Asn Arg Cys Lys Ala Tyr Met Cys Pro Phe Met Gln
                 365                 370                 375

 Phe Ile Glu Gly Gly Arg Arg Tyr Gln Cys Gly Phe Cys Asn Cys
                 380                 385                 390

 Val Asn Asp Val Pro Pro Phe Tyr Phe Gln His Leu Asp His Ile
                 395                 400                 405

 Gly Arg Arg Leu Asp His Tyr Glu Lys Pro Glu Leu Ser Leu Gly
                 410                 415                 420

 Ser Tyr Glu Tyr Val Ala Thr Leu Asp Tyr Cys Arg Lys Ser Lys
                 425                 430                 435

 Pro Pro Asn Pro Pro Ala Phe Ile Phe Met Ile Asp Val Ser Tyr
                 440                 445                 450

 Ser Asn Ile Lys Asn Gly Leu Val Lys Leu Ile Cys Glu Glu Leu
                 455                 460                 465

 Lys Thr Met Leu Glu Lys Ile Pro Lys Glu Glu Gln Glu Glu Thr
                 470                 475                 480

 Ser Ala Ile Arg Val Gly Phe Ile Thr Tyr Asn Lys Val Leu His
                 485                 490                 495

 Phe Phe Asn Val Lys Ser Asn Leu Ala Gln Pro Gln Met Met Val
                 500                 505                 510

 Val Thr Asp Val Gly Glu Val Phe Val Pro Leu Leu Asp Gly Phe
                 515                 520                 525

 Leu Val Asn Tyr Gln Glu Ser Gln Ser Val Ile His Asn Leu Leu
                 530                 535                 540

 Asp Gln Ile Pro Asp Met Phe Ala Asp Ser Asn Glu Asn Glu Thr
                 545                 550                 555

 Val Phe Ala Ser Val Ile Gln Ala Gly Met Glu Ala Leu Lys Ala
                 560                 565                 570

 Ala Asp Cys Pro Gly Lys Leu Phe Ile Phe His Ser Ser Leu Pro
                 575                 580                 585

 Thr Ala Glu Ala Pro Gly Lys Leu Lys Asn Arg Asp Asp Lys Lys
                 590                 595                 600

 Leu Val Asn Thr Asp Lys Glu Lys Ile Leu Phe Gln Pro Gln Thr
                 605                 610                 615

 Asn Val Tyr Asp Ser Leu Ala Lys Asp Cys Val Ala His Gly Cys
                 620                 625                 630

 Ser Val Thr Leu Phe Leu Phe Pro Ser Gln Tyr Val Asp Val Ala
                 635                 640                 645

 Ser Leu Gly Leu Val Pro Gln Leu Thr Gly Gly Thr Leu Tyr Lys
                 650                 655                 660

 Tyr Asn Asn Phe Gln Met His Leu Asp Arg Gln Gln Phe Leu Asn
                 665                 670                 675

 Asp Leu Arg Asn Asp Ile Glu Lys Lys Ile Gly Phe Asp Ala Ile
                 680                 685                 690

 Met Arg Val Arg Thr Ser Thr Gly Phe Arg Ala Thr Asp Phe Phe
                 695                 700                 705

 Gly Gly Ile Leu Met Asn Asn Thr Thr Asp Val Glu Met Ala Ala
                 710                 715                 720

 Ile Asp Cys Asp Lys Ala Val Thr Val Glu Phe Lys His Asp Asp
                 725                 730                 735

 Lys Leu Ser Glu Asp Ser Gly Ala Leu Ile Gln Cys Ala Val Leu
                 740                 745                 750

 Tyr Thr Thr Ile Ser Gly Gln Arg Arg Leu Arg Ile His Asn Leu
                 755                 760                 765

 Gly Leu Asn Cys Ser Ser Gln Leu Ala Asp Leu Tyr Lys Ser Cys
                 770                 775                 780

 Glu Thr Asp Ala Leu Ile Asn Phe Phe Ala Lys Ser Ala Phe Lys
                 785                 790                 795

 Ala Val Leu His Gln Pro Leu Lys Val Ile Arg Glu Ile Leu Val
                 800                 805                 810

 Asn Gln Thr Ala His Met Leu Ala Cys Tyr Arg Lys Asn Cys Ala
                 815                 820                 825

 Ser Pro Ser Ala Ala Ser Gln Leu Ile Leu Pro Asp Ser Met Lys
                 830                 835                 840

 Val Leu Pro Val Tyr Met Asn Cys Leu Leu Lys Asn Cys Val Leu
                 845                 850                 855

 Leu Ser Arg Pro Glu Ile Ser Thr Asp Glu Arg Ala Tyr Gln Arg
                 860                 865                 870

 Gln Leu Val Met Thr Met Gly Val Ala Asp Ser Gln Leu Phe Phe
                 875                 880                 885

 Tyr Pro Gln Leu Leu Pro Ile His Thr Leu Asp Val Lys Ser Thr
                 890                 895                 900

 Met Leu Pro Ala Ala Val Arg Cys Ser Glu Ser Arg Leu Ser Glu
                 905                 910                 915

 Glu Gly Ile Phe Leu Leu Ala Asn Gly Leu His Met Phe Leu Trp
                 920                 925                 930

 Leu Gly Val Ser Ser Pro Pro Glu Leu Ile Gln Gly Ile Phe Asn
                 935                 940                 945

 Val Pro Ser Phe Ala His Ile Asn Thr Asp Met Thr Leu Leu Pro
                 950                 955                 960

 Glu Val Gly Asn Pro Tyr Ser Gln Gln Leu Arg Met Ile Met Gly
                 965                 970                 975

 Ile Ile Gln Gln Lys Arg Pro Tyr Ser Met Lys Leu Thr Ile Val
                 980                 985                 990

 Lys Gln Arg Glu Gln Pro Glu Met Val Phe Arg Gln Phe Leu Val
                 995                1000                1005

 Glu Asp Lys Gly Leu Tyr Gly Gly Ser Ser Tyr Val Asp Phe Leu
                1010                1015                1020

 Cys Cys Val His Lys Glu Ile Cys Gln Leu Leu Asn
                1025                1030

<210> 5807
<211> 2475
<212> DNA
<213> Homo sapien

<400> 5807
 ccggaggagt ccgagaggaa gcggaggcgc gagctggagg cggcggctcc 50

 cgtcggcctc cggcaggact gagcgctggg aggccggaag gcgggcgcgc 100

 acggcggaga ggcgggcggg aggccggagc atattaatga aaagtgccat 150

 aaactgaaaa accaaacatg agggtagcag gtgctgcaaa gttggtggta 200

 gctgtggcag tgtttttact gacattttat gttatttctc aagtatttga 250

 aataaaaatg gatgcaagtt taggaaatct atttgcaaga tcagcattgg 300

 acacagctgc acgttctaca aagcctccca gatataagtg tgggatctca 350

 aaagcttgcc ctgagaagca ttttgctttt aaaatggcaa gtggagcagc 400

 caacgtggtg ggacccaaaa tctgcctgga agataatgtt ttaatgagtg 450

 gtgttaagaa taatgttgga agagggatca atgttgcctt ggcaaatgga 500

 aaaacaggag aagtattaga cactaaatat tttgacatgt ggggaggaga 550

 tgtggcacca tttattgagt ttctgaaggc catacaagat ggaacaatag 600

 ttttaatggg aacatacgat gatggagcaa ccaaactcaa tgatgaggca 650

 cggcggctca ttgctgattt ggggagcaca tctattacta atcttggttt 700

 tagagacaac tgggtcttct gtggtgggaa gggcattaag acaaaaagcc 750

 cttttgaaca gcacataaag aacaataagg atacaaacaa atatgaagga 800

 tggcctgaag ttgtagaaat ggaaggatgc atcccccaga agcaagacta 850

 atggaaatgt ggagagaatt gaagaaagcg cactttcact cttaatggga 900

 gagctataaa tggcagagct atgtgtaaat attttaagag catgcagcca 950

 tcttggtgtg tgcatgagta ttgtctcttt tgatatcagg attatttatt 1000

 gctaacgtaa atagatagca ttgtaaataa tcatcacaat gatcaaatca 1050

 ctgaaccatg tctccgcaca tttccctaaa agtacaatgt ttagactgct 1100

 atggtaatac atattttaaa ttctaaaagc atacacaatg tgtaactgaa 1150

 tggtttgtga aaaatatatt gatatatata ctagttgcta tgaaaatatc 1200

 atggaataat agggatttta gggtggatac tttattttct tttatgtttc 1250

 tatatgttgc gttgtgatga cattatcttt taaattaaaa agagatttgg 1300

 ctagttgtgt gtgtaatgtt actttacagt ccgactctcc tgatgtacct 1350

 cttttcatga tctttttctt tccttcccaa gaaactgagg aatgtttaat 1400

 atgaaaacat acatcggata tgtgaaaagc acaacaaaat tcttaatgta 1450

 cacagtaaaa aagtaaatat ataaatgtag atggcattta ggaccacagc 1500

 ttgctggatt tgtgttagct atgggaataa cttgattttg tataagctat 1550

 ttagagtgag gctggaggtg gcagcttcac agaactggag aaccaggcca 1600

 agtcccctcc ccaacctaat taggtcattc aggacagcta agtcagtata 1650

 tttagagcaa tactagcata cgtttttctt aattgttatc agcattgacc 1700

 aagtggtttg gaaggaggca tgctttaata tcacaataat tttgatttgt 1750

 aaaccaagaa attaatcctg tgtttatcta acttcataat agcaattatt 1800

 gcccgaagct atagtggcat atttacaaaa gttcttatta ctgggcggac 1850

 tgataacatt taaaaaataa ttgtgtttga ccccaaatga ctttataccc 1900

 aattctacat aaaaatatag aagatctatc tttttttgtt accttcagat 1950

 gttcactaaa taactcagtt tttaagcaga agttttcagg gcattaaata 2000

 tatgttgtgt atgaagtatc tcaaactgga acataaattt agtgatcaaa 2050

 ctgccattca cagtgtaagg cagcacttaa atttcgaacc taaagtttag 2100

 atgcattgta taaaaaaacc taaaagcagt atctgttatt tagctgtaaa 2150

 ccaagttgga agctattcgg ataatttctt aaatattgat gaactttgga 2200

 gtactgtttc ttccttcaaa ctgaatgtaa ttaattcatg aataaatgca 2250

 ccttatatgt ttaaacaatc tttgtatact tttgggattt ttggtgctta 2300

 tatgctaaat cacattcagc atgtgtattt tgacatttaa aatacttccc 2350

 tcaattctgt aaattaaaag aatagttatt ttacagttcc agggattgtg 2400

 aaataaatgt tgcagttttt taaaataatg aaaataaata ctcttggttt 2450

 tgctttgtga aaaaaaaaaa aaaaa 2475

<210> 5808
<211> 227
<212> PRT
<213> Homo sapien

<400> 5808
 Met Arg Val Ala Gly Ala Ala Lys Leu Val Val Ala Val Ala Val
   1               5                  10                  15

 Phe Leu Leu Thr Phe Tyr Val Ile Ser Gln Val Phe Glu Ile Lys
                  20                  25                  30

 Met Asp Ala Ser Leu Gly Asn Leu Phe Ala Arg Ser Ala Leu Asp
                  35                  40                  45

 Thr Ala Ala Arg Ser Thr Lys Pro Pro Arg Tyr Lys Cys Gly Ile
                  50                  55                  60

 Ser Lys Ala Cys Pro Glu Lys His Phe Ala Phe Lys Met Ala Ser
                  65                  70                  75

 Gly Ala Ala Asn Val Val Gly Pro Lys Ile Cys Leu Glu Asp Asn
                  80                  85                  90

 Val Leu Met Ser Gly Val Lys Asn Asn Val Gly Arg Gly Ile Asn
                  95                 100                 105

 Val Ala Leu Ala Asn Gly Lys Thr Gly Glu Val Leu Asp Thr Lys
                 110                 115                 120

 Tyr Phe Asp Met Trp Gly Gly Asp Val Ala Pro Phe Ile Glu Phe
                 125                 130                 135

 Leu Lys Ala Ile Gln Asp Gly Thr Ile Val Leu Met Gly Thr Tyr
                 140                 145                 150

 Asp Asp Gly Ala Thr Lys Leu Asn Asp Glu Ala Arg Arg Leu Ile
                 155                 160                 165

 Ala Asp Leu Gly Ser Thr Ser Ile Thr Asn Leu Gly Phe Arg Asp
                 170                 175                 180

 Asn Trp Val Phe Cys Gly Gly Lys Gly Ile Lys Thr Lys Ser Pro
                 185                 190                 195

 Phe Glu Gln His Ile Lys Asn Asn Lys Asp Thr Asn Lys Tyr Glu
                 200                 205                 210

 Gly Trp Pro Glu Val Val Glu Met Glu Gly Cys Ile Pro Gln Lys
                 215                 220                 225

 Gln Asp


<210> 5809
<211> 3025
<212> DNA
<213> Homo sapien

<400> 5809
 gcacgagcag gcagttcaga ttaaagaagc taattgatca agaaatcaag 50

 tctcaggagg agaaggagca agaaaaggag aaaagggtca ccaccctgaa 100

 agaggagctg accaagctga agtcttttgc tttgatggtg gtggatgaac 150

 agcaaaggct gacggcacag ctcacccttc aaagacagaa aatccaagag 200

 ctgaccacaa atgcaaagga aacacatacc aaactagccc ttgctgaagc 250

 cagagttcag gaggaagagc agaaggcaac cagactagag aaggaactgc 300

 aaacgcagac cacaaagttt caccaagacc aagacacaat tatggcgaag 350

 ctcaccaatg aggacagtca aaatcgccag cttcaacaaa agctggcagc 400

 actcagccgg cagattgatg agttagaaga gacaaacagg tctttacgaa 450

 aagcagaaga ggagctgcaa gatataaaag aaaaaatcag taagggagaa 500

 tatggaaacg ctggtatcat ggctgaagtg gaagagctca taaaaatgga 550

 ggagcagtgc agagatctca ataagaggct tgaaagggag acgttacaga 600

 gtaaagactt taaactagag gttgaaaaac tcagtaaaag aattatggct 650

 ctggaaaagt tagaagacgc tttcaacaaa agcaaacaag aatgctactc 700

 tctgaaatgc aatttagaaa aagaaaggat gaccacaaag cagttgtctc 750

 aagaactgga gagtttaaaa gtaaggatca aagagctaga agccattgaa 800

 agtcggctag aaaagacaga attcactcta aaagaggatt taactaaact 850

 gaaaacatta actgtgatgt ttgtagatga acggaaaaca atgagtgaaa 900

 aattaaagaa aactgaagat aaattacaag ctgcttcttc tcagcttcaa 950

 gtggagcaaa ataaagtaac aacagttact gagaagttaa ttgaggaaac 1000

 taaaagggcg ctcaagtcca aaaccgatgt agaagaaaag atgtacagcg 1050

 taaccaagga gagagatgat ttaaaaaaca aattgaaagc ggaagaagag 1100

 aaaggaaatg atctcctgtc aagagttaat atgttgaaaa ataggcttca 1150

 atcattggaa gcaattgaga aagatttcct aaaaaacaaa ttaaatcaag 1200

 actctgggaa atccacaaca gcattacacc aagaaaacaa taagattaag 1250

 gagctctctc aagaagtgga aagactgaaa ctgaagctaa aggacatgaa 1300

 agccattgag gatgacctca tgaaaacaga agatgaatat gagactctag 1350

 aacgaaggta tgctaatgaa cgagacaaag ctcaattttt atctaaagag 1400

 ctagaacatg ttaaaatgga acttgctaag tacaagttag cagaaaagac 1450

 agagaccagc catgaacaat ggcttttcaa aaggcttcaa gaagaagaag 1500

 ctaagtcagg gcacctctca agagaagtgg atgcattaaa agagaaaatt 1550

 catgaataca tggcaactga agacctaata tgtcacctcc agggagatca 1600

 ctcagtctgc aaaaaaaaac taaatcaaca agaaaacagg aacagagatt 1650

 taggaagaga gattgaaaac ctcactaagg agttagagag gtaccggcat 1700

 ttcagtaaga gcctcaggcc tagtctcaat ggaagaagaa tttccgatcc 1750

 tcaagtattt tctaaagaag ttcagacaga agcagtagac aatgaaccac 1800

 ctgattacaa gagcctcatt cctctggaac gtgcagtcat caatggtcag 1850

 ttatatgagg agagtgagaa tcaagacgag gaccctaatg atgagggatc 1900

 tgtgctgtcc ttcaaatgca gccagtctac tccatgtcct gttaacagaa 1950

 agctatggat tccctggatg aaatccaagg agggccatct tcagaatgga 2000

 aaaatgcaaa ctaaacccaa tgccaacttt gtgcaacctg gagatctagt 2050

 cctaagccac acacctgggc agccacttca tataaaggtt actccagacc 2100

 atgtacaaaa cacagccact cttgaaatca caagtccaac cacagagagt 2150

 cctcactctt acacgagtac tgcagtgata ccgaactgtg gcacgccaaa 2200

 gcaaaggata accatcctcc aaaacgcctc cataacacca gtaaagtcca 2250

 aaacctctac cgaagacctc atgaatttag aacaaggcat gtccccaatt 2300

 accatggcaa cctttgccag agcacagacc ccagagtctt gtggttctct 2350

 aactccagaa aggacaatgt ccctattcag gttttggctg tgactggttc 2400

 agctagctct cctgagcagg gacgctcccc agaaccaaca gaaatcagtg 2450

 ccaagcatgc gatattcaga gtctccccag accggcagtc atcatggcag 2500

 tttcagcgtt caaacagcaa tagctcaagt gtgataacta ctgaggataa 2550

 taaaatccac attcacttag gaagtcctta catgcaagct gtagccagcc 2600

 cttcagcacc actgcaggat aaccgaactc aaggcttaat taacggggca 2650

 ctaaacaaaa caaccaataa agtcaccagc agtattacta tcacaccaac 2700

 agccacacct cttcctcgac aatcacaaat tacagtaagt aatatatata 2750

 actgaccacg ctcaccctca tccagtccat actgatattt ttgcaaggaa 2800

 ctcaatcctt ttttaatcat ccctccatat cccccaagac tgactgaact 2850

 cgtactttgg gaaggtttgt gcatgaacta tacaagagta tctgaaacta 2900

 actgttgcct gcatagtcat atcgagtgtg cacttactgt atatcttttc 2950

 atttacatac ttgtatggaa aatatttagt ctgcacttgt ataaatacat 3000

 ctttatgtat ttgaaaaaaa aaaaa 3025

<210> 5810
<211> 752
<212> PRT
<213> Homo sapien

<400> 5810
 Met Val Val Asp Glu Gln Gln Arg Leu Thr Ala Gln Leu Thr Leu
   1               5                  10                  15

 Gln Arg Gln Lys Ile Gln Glu Leu Thr Thr Asn Ala Lys Glu Thr
                  20                  25                  30

 His Thr Lys Leu Ala Leu Ala Glu Ala Arg Val Gln Glu Glu Glu
                  35                  40                  45

 Gln Lys Ala Thr Arg Leu Glu Lys Glu Leu Gln Thr Gln Thr Thr
                  50                  55                  60

 Lys Phe His Gln Asp Gln Asp Thr Ile Met Ala Lys Leu Thr Asn
                  65                  70                  75

 Glu Asp Ser Gln Asn Arg Gln Leu Gln Gln Lys Leu Ala Ala Leu
                  80                  85                  90

 Ser Arg Gln Ile Asp Glu Leu Glu Glu Thr Asn Arg Ser Leu Arg
                  95                 100                 105

 Lys Ala Glu Glu Glu Leu Gln Asp Ile Lys Glu Lys Ile Ser Lys
                 110                 115                 120

 Gly Glu Tyr Gly Asn Ala Gly Ile Met Ala Glu Val Glu Glu Leu
                 125                 130                 135

 Ile Lys Met Glu Glu Gln Cys Arg Asp Leu Asn Lys Arg Leu Glu
                 140                 145                 150

 Arg Glu Thr Leu Gln Ser Lys Asp Phe Lys Leu Glu Val Glu Lys
                 155                 160                 165

 Leu Ser Lys Arg Ile Met Ala Leu Glu Lys Leu Glu Asp Ala Phe
                 170                 175                 180

 Asn Lys Ser Lys Gln Glu Cys Tyr Ser Leu Lys Cys Asn Leu Glu
                 185                 190                 195

 Lys Glu Arg Met Thr Thr Lys Gln Leu Ser Gln Glu Leu Glu Ser
                 200                 205                 210

 Leu Lys Val Arg Ile Lys Glu Leu Glu Ala Ile Glu Ser Arg Leu
                 215                 220                 225

 Glu Lys Thr Glu Phe Thr Leu Lys Glu Asp Leu Thr Lys Leu Lys
                 230                 235                 240

 Thr Leu Thr Val Met Phe Val Asp Glu Arg Lys Thr Met Ser Glu
                 245                 250                 255

 Lys Leu Lys Lys Thr Glu Asp Lys Leu Gln Ala Ala Ser Ser Gln
                 260                 265                 270

 Leu Gln Val Glu Gln Asn Lys Val Thr Thr Val Thr Glu Lys Leu
                 275                 280                 285

 Ile Glu Glu Thr Lys Arg Ala Leu Lys Ser Lys Thr Asp Val Glu
                 290                 295                 300

 Glu Lys Met Tyr Ser Val Thr Lys Glu Arg Asp Asp Leu Lys Asn
                 305                 310                 315

 Lys Leu Lys Ala Glu Glu Glu Lys Gly Asn Asp Leu Leu Ser Arg
                 320                 325                 330

 Val Asn Met Leu Lys Asn Arg Leu Gln Ser Leu Glu Ala Ile Glu
                 335                 340                 345

 Lys Asp Phe Leu Lys Asn Lys Leu Asn Gln Asp Ser Gly Lys Ser
                 350                 355                 360

 Thr Thr Ala Leu His Gln Glu Asn Asn Lys Ile Lys Glu Leu Ser
                 365                 370                 375

 Gln Glu Val Glu Arg Leu Lys Leu Lys Leu Lys Asp Met Lys Ala
                 380                 385                 390

 Ile Glu Asp Asp Leu Met Lys Thr Glu Asp Glu Tyr Glu Thr Leu
                 395                 400                 405

 Glu Arg Arg Tyr Ala Asn Glu Arg Asp Lys Ala Gln Phe Leu Ser
                 410                 415                 420

 Lys Glu Leu Glu His Val Lys Met Glu Leu Ala Lys Tyr Lys Leu
                 425                 430                 435

 Ala Glu Lys Thr Glu Thr Ser His Glu Gln Trp Leu Phe Lys Arg
                 440                 445                 450

 Leu Gln Glu Glu Glu Ala Lys Ser Gly His Leu Ser Arg Glu Val
                 455                 460                 465

 Asp Ala Leu Lys Glu Lys Ile His Glu Tyr Met Ala Thr Glu Asp
                 470                 475                 480

 Leu Ile Cys His Leu Gln Gly Asp His Ser Val Cys Lys Lys Lys
                 485                 490                 495

 Leu Asn Gln Gln Glu Asn Arg Asn Arg Asp Leu Gly Arg Glu Ile
                 500                 505                 510

 Glu Asn Leu Thr Lys Glu Leu Glu Arg Tyr Arg His Phe Ser Lys
                 515                 520                 525

 Ser Leu Arg Pro Ser Leu Asn Gly Arg Arg Ile Ser Asp Pro Gln
                 530                 535                 540

 Val Phe Ser Lys Glu Val Gln Thr Glu Ala Val Asp Asn Glu Pro
                 545                 550                 555

 Pro Asp Tyr Lys Ser Leu Ile Pro Leu Glu Arg Ala Val Ile Asn
                 560                 565                 570

 Gly Gln Leu Tyr Glu Glu Ser Glu Asn Gln Asp Glu Asp Pro Asn
                 575                 580                 585

 Asp Glu Gly Ser Val Leu Ser Phe Lys Cys Ser Gln Ser Thr Pro
                 590                 595                 600

 Cys Pro Val Asn Arg Lys Leu Trp Ile Pro Trp Met Lys Ser Lys
                 605                 610                 615

 Glu Gly His Leu Gln Asn Gly Lys Met Gln Thr Lys Pro Asn Ala
                 620                 625                 630

 Asn Phe Val Gln Pro Gly Asp Leu Val Leu Ser His Thr Pro Gly
                 635                 640                 645

 Gln Pro Leu His Ile Lys Val Thr Pro Asp His Val Gln Asn Thr
                 650                 655                 660

 Ala Thr Leu Glu Ile Thr Ser Pro Thr Thr Glu Ser Pro His Ser
                 665                 670                 675

 Tyr Thr Ser Thr Ala Val Ile Pro Asn Cys Gly Thr Pro Lys Gln
                 680                 685                 690

 Arg Ile Thr Ile Leu Gln Asn Ala Ser Ile Thr Pro Val Lys Ser
                 695                 700                 705

 Lys Thr Ser Thr Glu Asp Leu Met Asn Leu Glu Gln Gly Met Ser
                 710                 715                 720

 Pro Ile Thr Met Ala Thr Phe Ala Arg Ala Gln Thr Pro Glu Ser
                 725                 730                 735

 Cys Gly Ser Leu Thr Pro Glu Arg Thr Met Ser Leu Phe Arg Phe
                 740                 745                 750

 Trp Leu


<210> 5811
<211> 837
<212> DNA
<213> Homo sapien

<400> 5811
 gaattccgcg gcggcgcctc aatgcctaaa ggaggaagaa agggaggcca 50

 caaaggccgg gcgaggcagt atacaagccc tgaggagatc gacgcgcagc 100

 tgcaggctga gaagcagaag gccagggaag aagaggagca aaaagaaggt 150

 ggagatgggg ctgcaggtga ccccaaaaag gagaagaaat ctctagactc 200

 agatgagagt gaggatgaag aagatgacta ccagcaaaag cgcaaaggcg 250

 ttgaagggct catcgacatc gagaacccca accgggtggc acagacaacc 300

 aaaaaggtca cacaactgga tctggacggg ccaaaggagc tttcgaggag 350

 agaacgagaa gagattgaga agcagaaggc aaaagagcgt tacatgaaaa 400

 tgcacttggc cgggaagaca gagcaagcca aggctgacct ggcccggctg 450

 gccatcatcc ggaaacagcg ggaggaggct gcccggaaga aggaagagga 500

 aaggaaagca aaagacgatg ccacattgtc aggaaaacga atgcagtcac 550

 tctccctgaa taagtaactg cgacccgtgg gaggagatgc cggggacctg 600

 ggccgcgctg ccaggacctc tgctgtgtct cgcccaccct gtgccctggc 650

 gccgctgcaa cagcccctca tggccaggag ccccccatgc ctgggcctcc 700

 tcttcatctt ggcacagaaa ttgtttgggg gatggggggg ggactggggg 750

 aggggtagct gctatctttg agacagaaag atgcaggaca gcatttcata 800

 tgtaaccatt tgaatgtttt tgctgttttt agaattc 837

<210> 5812
<211> 181
<212> PRT
<213> Homo sapien

<400> 5812
 Met Pro Lys Gly Gly Arg Lys Gly Gly His Lys Gly Arg Ala Arg
   1               5                  10                  15

 Gln Tyr Thr Ser Pro Glu Glu Ile Asp Ala Gln Leu Gln Ala Glu
                  20                  25                  30

 Lys Gln Lys Ala Arg Glu Glu Glu Glu Gln Lys Glu Gly Gly Asp
                  35                  40                  45

 Gly Ala Ala Gly Asp Pro Lys Lys Glu Lys Lys Ser Leu Asp Ser
                  50                  55                  60

 Asp Glu Ser Glu Asp Glu Glu Asp Asp Tyr Gln Gln Lys Arg Lys
                  65                  70                  75

 Gly Val Glu Gly Leu Ile Asp Ile Glu Asn Pro Asn Arg Val Ala
                  80                  85                  90

 Gln Thr Thr Lys Lys Val Thr Gln Leu Asp Leu Asp Gly Pro Lys
                  95                 100                 105

 Glu Leu Ser Arg Arg Glu Arg Glu Glu Ile Glu Lys Gln Lys Ala
                 110                 115                 120

 Lys Glu Arg Tyr Met Lys Met His Leu Ala Gly Lys Thr Glu Gln
                 125                 130                 135

 Ala Lys Ala Asp Leu Ala Arg Leu Ala Ile Ile Arg Lys Gln Arg
                 140                 145                 150

 Glu Glu Ala Ala Arg Lys Lys Glu Glu Glu Arg Lys Ala Lys Asp
                 155                 160                 165

 Asp Ala Thr Leu Ser Gly Lys Arg Met Gln Ser Leu Ser Leu Asn
                 170                 175                 180

 Lys


<210> 5813
<211> 4565
<212> DNA
<213> Homo sapien

<400> 5813
 ggcgagctaa gccggaggat gtgcagctgc ggcggcggcg ccggctacga 50

 agaggacggg gacaggcgcc gtgcgaaccg agcccagcca gccggaggac 100

 gcgggcaggg cgggacggga gcccggactc gtctgccgcc gccgtcgtcg 150

 ccgtcgtgcc ggccccgcgt ccccgcgcgc gagcgggagg agccgccgcc 200

 acctcgcgcc cgagccgccg ctagcgcgcg ccgggcatgg tcccctctta 250

 aaggcgcagg ccgcggcggc gggggcgggc gtgcggaaca aagcgccggc 300

 gcggggcctg cgggcggctc gggggccgcg atgggcgcgg cgggcccgcg 350

 gcggcggcgg cgctgcccgg gccgggcctc gcggcgctag ggcgggctgg 400

 cctccgcggg cgggggcagc gggctgaggg cgcgcggggc ctgcggcggc 450

 ggcggcggcg gcggcggcgg cccggcgggc ggagcggcgc gggcatggcc 500

 gcgcgcggcc ggcgcgcctg gctcagcgtg ctgctcgggc tcgtcctggg 550

 cttcgtgctg gcctcgcggc tcgtcctgcc ccgggcttcc gagctgaagc 600

 gagcgggccc acggcgccgc gccagccccg agggctgccg gtccgggcag 650

 gcggcggctt cccaggccgg cggggcgcgc ggcgatgcgc gcggggcgca 700

 gctctggccg cccggctcgg acccagatgg cggcccgcgc gacaggaact 750

 ttctcttcgt gggagtcatg accgcccaga aatacctgca gactcgggcc 800

 gtggccgcct acagaacatg gtccaagaca attcctggga aagttcagtt 850

 cttctcaagt gagggttctg acacatctgt accaattcca gtagtgccac 900

 tacggggtgt ggacgactcc tacccgcccc agaagaagtc cttcatgatg 950

 ctcaagtaca tgcacgacca ctacttggac aagtatgaat ggtttatgag 1000

 agcagatgat gacgtgtaca tcaaaggaga ccgtctggag aacttcctga 1050

 ggagtttgaa cagcagcgag cccctctttc ttgggcagac aggcctgggc 1100

 accacggaag aaatgggaaa actggccctg gagcctggtg agaacttctg 1150

 catggggggg cctggcgtga tcatgagccg ggaggtgctt cggagaatgg 1200

 tgccgcacat tggcaagtgt ctccgggaga tgtacaccac ccatgaggac 1250

 gtggaggtgg gaaggtgtgt ccggaggttt gcaggggtgc agtgtgtctg 1300

 gtcttatgag atgcagcagc ttttttatga gaattacgag cagaacaaaa 1350

 aggggtacat tagagatctc cataacagta aaattcacca agctatcaca 1400

 ttacacccca acaaaaaccc accctaccag tacaggctcc acagctacat 1450

 gctgagccgc aagatatccg agctccgcca tcgcacaata cagctgcacc 1500

 gcgaaattgt cctgatgagc aaatacagca acacagaaat tcataaagag 1550

 gacctccagc tgggaatccc tccctccttc atgaggtttc agccccgcca 1600

 gcgagaggag attctggaat gggagtttct gactggaaaa tacttgtatt 1650

 cggcagttga cggccagccc cctcgaagag gaatggactc cgcccagagg 1700

 gaagccttgg acgacattgt catgcaggtc atggagatga tcaatgccaa 1750

 cgccaagacc agagggcgca tcattgactt caaagagatc cagtacggct 1800

 accgccgggt gaaccccatg tatggggctg agtacatcct ggacctgctg 1850

 cttctgtaca aaaagcacaa agggaagaaa atgacggtcc ctgtgaggag 1900

 gcacgcgtat ttacagcaga ctttcagcaa aatccagttt gtggagcatg 1950

 aggagctgga tgcacaagag ttggccaaga gaatcaatca ggaatctgga 2000

 tccttgtcct ttctctcaaa ctccctgaag aagctcgtcc cctttcagct 2050

 ccctgggtcg aagagtgagc acaaagaacc caaagataaa aagataaaca 2100

 tactgattcc tttgtctggg cgtttcgaca tgtttgtgag atttatggga 2150

 aactttgaga agacgtgtct tatccccaat cagaacgtca agctcgtggt 2200

 tctgcttttc aattctgact ccaaccctga caaggccaaa caagttgaac 2250

 tgatgacaga ttaccgcatt aagtacccta aagccgacat gcagattttg 2300

 cctgtgtctg gagagttttc aagagccctg gccctggaag taggatcctc 2350

 ccagtttaac aatgaatctt tgctcttctt ctgcgacgtc gacctcgtct 2400

 ttactacaga attccttcag cgatgtcgag caaatacagt tctgggccaa 2450

 caaatatatt ttccaatcat cttcagccag tatgacccaa agattgttta 2500

 tagtgggaaa gttcccagtg acaaccattt tgcctttact cagaaaactg 2550

 gcttctggag aaactatggg tttggcatca cgtgtattta taagggagat 2600

 cttgtccgag tgggtggctt tgatgtttcc atccaaggct gggggctgga 2650

 ggatgtggac cttttcaaca aggttgtcca ggcaggtttg aagacgttta 2700

 ggagccagga agtaggagta gtccacgtcc accatcctgt cttttgtgat 2750

 cccaatcttg accccaaaca gtacaaaatg tgcttggggt ccaaagcatc 2800

 gacctatggg tccacacagc agctggctga gatgtggctg gaaaaaaatg 2850

 atccaagtta cagtaaaagc agcaataata atggctcagt gaggacagcc 2900

 taatgtccag ctttgctgga aaagacgttt ttaattatct aatttatttt 2950

 tcaaaaattt tttgtatgat cagtttttga agtccgtata caaggatata 3000

 ttttacaagt ggttttctta cataggactc ctttaagatt gagctttctg 3050

 aacaagaagg tgatcagtgt ttgcctttga acacatcttc ttgctgaaca 3100

 ttatgtagca gacctgctta actttgactt gaaatgtacc tgatgaacaa 3150

 aactttttta aaaaaatgtt ttcttttgag accctttgct ccagtcctat 3200

 ggcagaaaac gtgaacattc ctgcaaagta ttattgtaac aaaacactgt 3250

 aactctggta aatgttctgt tgtgattgtt aacattccac agattctacc 3300

 ttttgtgttt tgtttttttt tttttacaat tgttttaaag ccatttcatg 3350

 ttccagttgt aagataagga aatgtgataa tagctgtttc atcattgtct 3400

 tcaggagagc tttccagagt tgatcatttc ccctcatggt actctgctca 3450

 gcatggccac gtaggttttt tgtttgtttt gttttgttct ttttttgaga 3500

 cggagtctca ctctgttacc caggctggaa tgcagtggcg caatcttggc 3550

 tcactttaac ctccacttcc ctggttcaag caattcccct gcctttgcct 3600

 cccgagtagc tgggattaca ggcacacacc accacgccca gctagttttt 3650

 ttgtattttt agtagagacg gggtttcacc atgcaagccc agctggccac 3700

 gtaggtttta aagcaagggg cgtgaagaag gcacagtgag gtatgtggct 3750

 gttctcgtgg tagttcattc ggcctaaata gacctggcat taaatttcaa 3800

 gaaggatttg gcattttctc ttcttgaccc ttctctttaa agggtaaaat 3850

 attaatgttt agaatgacaa agatgaatta ttacaataaa tctgatgtac 3900

 acagactgaa acacacacac atacacccta atcaaaacgt tggggaaaaa 3950

 tgtatttggt tttgttcctt tcatcctgtc tgtgttatgt gggtggagat 4000

 ggttttcatt ctttcattac tgttttgttt tatcctttgt atctgaaata 4050

 cctttaattt atttaatatc tgttgttcag agctctgcca tttcttgagt 4100

 acctgttagt tagtattatt tatgtgtatc gggagtgtgt ttagtctgtt 4150

 ttatttgcag taaaccgatc tccaaagatt tccttttgga aacgcttttt 4200

 cccctcctta atttttatat tccttactgt tttactaaat attaagtgtt 4250

 ctttgacaat tttggtgctc atgtgttttg gggacaaaag tgaaatgaat 4300

 ctgtcattat accagaaagt taaattctca gatcaaatgt gccttaataa 4350

 atttgttttc atttagattt caaacagtga tagacttgcc attttaatac 4400

 acgtcattgg agggctgcgt atttgtaaat agcctgatgc tcatttggaa 4450

 aaataaacca gtgaacaata tttttctatt gtacttttca gaaccatttt 4500

 gtctcattat tcctgtttta gctgaagaat tgtattacat ttggagagta 4550

 aaaaacttaa acacg 4565

<210> 5814
<211> 802
<212> PRT
<213> Homo sapien

<400> 5814
 Met Ala Ala Arg Gly Arg Arg Ala Trp Leu Ser Val Leu Leu Gly
   1               5                  10                  15

 Leu Val Leu Gly Phe Val Leu Ala Ser Arg Leu Val Leu Pro Arg
                  20                  25                  30

 Ala Ser Glu Leu Lys Arg Ala Gly Pro Arg Arg Arg Ala Ser Pro
                  35                  40                  45

 Glu Gly Cys Arg Ser Gly Gln Ala Ala Ala Ser Gln Ala Gly Gly
                  50                  55                  60

 Ala Arg Gly Asp Ala Arg Gly Ala Gln Leu Trp Pro Pro Gly Ser
                  65                  70                  75

 Asp Pro Asp Gly Gly Pro Arg Asp Arg Asn Phe Leu Phe Val Gly
                  80                  85                  90

 Val Met Thr Ala Gln Lys Tyr Leu Gln Thr Arg Ala Val Ala Ala
                  95                 100                 105

 Tyr Arg Thr Trp Ser Lys Thr Ile Pro Gly Lys Val Gln Phe Phe
                 110                 115                 120

 Ser Ser Glu Gly Ser Asp Thr Ser Val Pro Ile Pro Val Val Pro
                 125                 130                 135

 Leu Arg Gly Val Asp Asp Ser Tyr Pro Pro Gln Lys Lys Ser Phe
                 140                 145                 150

 Met Met Leu Lys Tyr Met His Asp His Tyr Leu Asp Lys Tyr Glu
                 155                 160                 165

 Trp Phe Met Arg Ala Asp Asp Asp Val Tyr Ile Lys Gly Asp Arg
                 170                 175                 180

 Leu Glu Asn Phe Leu Arg Ser Leu Asn Ser Ser Glu Pro Leu Phe
                 185                 190                 195

 Leu Gly Gln Thr Gly Leu Gly Thr Thr Glu Glu Met Gly Lys Leu
                 200                 205                 210

 Ala Leu Glu Pro Gly Glu Asn Phe Cys Met Gly Gly Pro Gly Val
                 215                 220                 225

 Ile Met Ser Arg Glu Val Leu Arg Arg Met Val Pro His Ile Gly
                 230                 235                 240

 Lys Cys Leu Arg Glu Met Tyr Thr Thr His Glu Asp Val Glu Val
                 245                 250                 255

 Gly Arg Cys Val Arg Arg Phe Ala Gly Val Gln Cys Val Trp Ser
                 260                 265                 270

 Tyr Glu Met Gln Gln Leu Phe Tyr Glu Asn Tyr Glu Gln Asn Lys
                 275                 280                 285

 Lys Gly Tyr Ile Arg Asp Leu His Asn Ser Lys Ile His Gln Ala
                 290                 295                 300

 Ile Thr Leu His Pro Asn Lys Asn Pro Pro Tyr Gln Tyr Arg Leu
                 305                 310                 315

 His Ser Tyr Met Leu Ser Arg Lys Ile Ser Glu Leu Arg His Arg
                 320                 325                 330

 Thr Ile Gln Leu His Arg Glu Ile Val Leu Met Ser Lys Tyr Ser
                 335                 340                 345

 Asn Thr Glu Ile His Lys Glu Asp Leu Gln Leu Gly Ile Pro Pro
                 350                 355                 360

 Ser Phe Met Arg Phe Gln Pro Arg Gln Arg Glu Glu Ile Leu Glu
                 365                 370                 375

 Trp Glu Phe Leu Thr Gly Lys Tyr Leu Tyr Ser Ala Val Asp Gly
                 380                 385                 390

 Gln Pro Pro Arg Arg Gly Met Asp Ser Ala Gln Arg Glu Ala Leu
                 395                 400                 405

 Asp Asp Ile Val Met Gln Val Met Glu Met Ile Asn Ala Asn Ala
                 410                 415                 420

 Lys Thr Arg Gly Arg Ile Ile Asp Phe Lys Glu Ile Gln Tyr Gly
                 425                 430                 435

 Tyr Arg Arg Val Asn Pro Met Tyr Gly Ala Glu Tyr Ile Leu Asp
                 440                 445                 450

 Leu Leu Leu Leu Tyr Lys Lys His Lys Gly Lys Lys Met Thr Val
                 455                 460                 465

 Pro Val Arg Arg His Ala Tyr Leu Gln Gln Thr Phe Ser Lys Ile
                 470                 475                 480

 Gln Phe Val Glu His Glu Glu Leu Asp Ala Gln Glu Leu Ala Lys
                 485                 490                 495

 Arg Ile Asn Gln Glu Ser Gly Ser Leu Ser Phe Leu Ser Asn Ser
                 500                 505                 510

 Leu Lys Lys Leu Val Pro Phe Gln Leu Pro Gly Ser Lys Ser Glu
                 515                 520                 525

 His Lys Glu Pro Lys Asp Lys Lys Ile Asn Ile Leu Ile Pro Leu
                 530                 535                 540

 Ser Gly Arg Phe Asp Met Phe Val Arg Phe Met Gly Asn Phe Glu
                 545                 550                 555

 Lys Thr Cys Leu Ile Pro Asn Gln Asn Val Lys Leu Val Val Leu
                 560                 565                 570

 Leu Phe Asn Ser Asp Ser Asn Pro Asp Lys Ala Lys Gln Val Glu
                 575                 580                 585

 Leu Met Thr Asp Tyr Arg Ile Lys Tyr Pro Lys Ala Asp Met Gln
                 590                 595                 600

 Ile Leu Pro Val Ser Gly Glu Phe Ser Arg Ala Leu Ala Leu Glu
                 605                 610                 615

 Val Gly Ser Ser Gln Phe Asn Asn Glu Ser Leu Leu Phe Phe Cys
                 620                 625                 630

 Asp Val Asp Leu Val Phe Thr Thr Glu Phe Leu Gln Arg Cys Arg
                 635                 640                 645

 Ala Asn Thr Val Leu Gly Gln Gln Ile Tyr Phe Pro Ile Ile Phe
                 650                 655                 660

 Ser Gln Tyr Asp Pro Lys Ile Val Tyr Ser Gly Lys Val Pro Ser
                 665                 670                 675

 Asp Asn His Phe Ala Phe Thr Gln Lys Thr Gly Phe Trp Arg Asn
                 680                 685                 690

 Tyr Gly Phe Gly Ile Thr Cys Ile Tyr Lys Gly Asp Leu Val Arg
                 695                 700                 705

 Val Gly Gly Phe Asp Val Ser Ile Gln Gly Trp Gly Leu Glu Asp
                 710                 715                 720

 Val Asp Leu Phe Asn Lys Val Val Gln Ala Gly Leu Lys Thr Phe
                 725                 730                 735

 Arg Ser Gln Glu Val Gly Val Val His Val His His Pro Val Phe
                 740                 745                 750

 Cys Asp Pro Asn Leu Asp Pro Lys Gln Tyr Lys Met Cys Leu Gly
                 755                 760                 765

 Ser Lys Ala Ser Thr Tyr Gly Ser Thr Gln Gln Leu Ala Glu Met
                 770                 775                 780

 Trp Leu Glu Lys Asn Asp Pro Ser Tyr Ser Lys Ser Ser Asn Asn
                 785                 790                 795

 Asn Gly Ser Val Arg Thr Ala
                 800

<210> 5815
<211> 3851
<212> DNA
<213> Homo sapien

<400> 5815
 gccgcggctc atgcgcggtg cacagaggct tgtttcacat ctgtaacaac 50

 aggaggaggc ccagcctcgt gatgaggaat agcaaggaga gaattcagct 100

 ccagttcaaa agcctacaaa atctgagact gtcattgctt ttataaggat 150

 tccagctttc cctcctggcc agaaatgttc agcctggact cattcagaaa 200

 agatcgggcc cagcacaggc agcgtcagtg caaacttccc ccaccccgcc 250

 ttccacccat gtgtgtcaac cctaccccag gagggaccat ctctcgagct 300

 tctagggacc tattaaaaga gttcccacag cccaaaaatc ttctcaacag 350

 tgtgattgga agagccctcg gcatctcaca tgcaaaagac aaactagtct 400

 acgtgcacac aaatggaccg aagaaaaaga aagtcacact gcacataaaa 450

 tggcccaaga gcgtggaggt agaaggctat ggcagcaaga agatcgatgc 500

 tgagcggcag gctgcagctg cagcctgcca gctgttcaag ggttggggtc 550

 tgctaggtcc ccggaatgag ttgtttgacg cagccaaata ccgagtgcta 600

 gctgatcgct ttggctcccc tgccgacagc tggtggcgtc cggaacccac 650

 catgccccct acttcctggc ggcagctgaa tccagagagt attcgaccag 700

 ggggacctgg gggcctatcc cgctctttag gccgggaaga agaggaggac 750

 gaggaggaag agctagaaga agggaccata gatgttaccg acttcttgtc 800

 catgacccag caggattccc acgctccact cagggactca agggggagtt 850

 cctttgagat gacagatgac gacagtgcca ttagggctct gacccagttt 900

 ccacttccca agaaccttct ggccaaggtg attcagattg caacgtcatc 950

 ctccacagct aagaacctca tgcagttcca tactgtgggc accaagacca 1000

 agctgtctac actcaccctg ctctggccct gccccatgac ctttgttgcc 1050

 aaagggcgcc gcaaagcaga ggctgagaat aaggcggcag ccttggcctg 1100

 caagaaactg aagagcctgg gcctggtgga caggaacaac gaaccgctta 1150

 cacacgccat gtataacctg gcctctttgc gtgagctggg tgagacccag 1200

 cgccgaccat gcaccatcca ggtgcccgag cccatcctcc gcaagataga 1250

 gaccttcctg aaccattacc ctgtggagag ttcatggatc gccccagaac 1300

 tccggctgca gagtgatgac atcttgccct tgggcaagga ctcagggcct 1350

 ctgagtgacc ctatcacagg caagccctat gtgcccctgt tggaagcaga 1400

 ggaggtacgt ctcagccaga gtctgctaga actgtggcgg cggcgagggc 1450

 cggtctggca ggaggccccc cagctacctg tggacccaca tcgggacacc 1500

 atcctcaacg ccattgagca gcacccggtg gtggtcatct ctggggacac 1550

 gggctgtggg aagaccacgc gcatccccca gctgttgctg gagcgctatg 1600

 tgaccgaggg ccgaggtgcc cgctgcaatg ttatcatcac ccaacctcgc 1650

 cgcatctctg ctgtgtctgt ggcacagcgg gtcagccacg aactgggccc 1700

 ctccctgcgc cggaatgtgg gcttccaggt gcggttggaa agtaagcccc 1750

 catcccgagg cggggccctg ctcttctgca ctgtgggtat cctgctgcgt 1800

 aagctgcaga gcaaccccag cctggagggc gtgagccacg tcatcgtgga 1850

 tgaggtgcat gagcgggacg tgaacacaga ctttctgctg atcctgctca 1900

 agggcctgca gcggctcaac ccggccctgc ggctggtgct catgagtgcc 1950

 acaggggaca atgagcgctt ctcccgatac tttggtggct gccccgtcat 2000

 caaggtgcct ggcttcatgt acccagtcaa ggagcactac ctagaggaca 2050

 tcctggccaa gttgggcaag caccagtacc tgcaccggca ccggcaccat 2100

 gagtctgagg atgaatgcgc actcgatttg gaccttgtga ctgatctggt 2150

 tctgcacatc gatgctcgcg gggaaccagg tgggatcctg tgcttcctgc 2200

 ctgggtggca ggagatcaaa ggagtgcagc agcgcctcca ggaggccctg 2250

 ggcatgcacg agagcaagta cctcatcctg ccagtgcact ccaacatccc 2300

 catgatggat cagaaggcca tattccagca gcctccagtt ggggtgcgca 2350

 agattgtctt ggccaccaac attgctgaga cttccatcac aatcaatgac 2400

 atcgtgcatg tggtggacag tgggctgcac aaggaagaac gctatgacct 2450

 gaagaccaag gtgtcctgcc tggagacagt gtgggtatca agagccaatg 2500

 tgatccagcg ccggggccgg gcgggccgct gccagtccgg ctttgcctac 2550

 cacttgttcc ctcgaagccg gctggagaaa atggtccctt tccaagtgcc 2600

 agagatcctg cgcacacctc ttgagaacct ggtgctgcaa gcgaaaatcc 2650

 acatgcctga gaagacggcg gtggagttcc tgtccaaggc tgtggacagt 2700

 ccaaacatca aggcagtgga cgaggctgtg atcttgctcc aggagatcgg 2750

 ggtgctggac cagcgggagt acctgactac cctggggcag cgcctggctc 2800

 acatctccac cgacccccgg ttggccaagg ccattgtgtt ggctgccatc 2850

 ttccgttgcc tgcacccact actggtggtc gtttcctgcc tcacccggga 2900

 ccccttcagc agcagcctac agaaccgggc agaggtggac aaggtgaaag 2950

 cactgttgag ccatgacagc ggcagtgacc acctggcctt tgtgcgggct 3000

 gtcgccggct gggaggaggt gctgcgttgg caggaccgca gctcccggga 3050

 gaattacctg gaggaaaacc tgctgtacgc acccagcctg cgcttcatcc 3100

 acggactcat caagcagttc tcagagaaca tttatgaggc cttcctggtg 3150

 gggaagccct cggactgcac cctggcctcc gcccagtgca acgagtacag 3200

 tgaggaggag gagctggtga agggcgtgct gatggccggc ctctacccca 3250

 acctcatcca ggtgaggcag ggcaaggtca cccggcaggg gaagttcaag 3300

 cccaacagcg tcacatatag gaccaaatca ggcaacatcc tgctgcacaa 3350

 gtcgaccatt aacagggagg ccacacggtt acggagccga tggctgacgt 3400

 atttcatggc agtcaagtcc aatggcagcg tcttcgtccg ggactcctct 3450

 caggtgcacc cgctagctgt gctgctgctg accgacgggg acgtgcacat 3500

 ccgtgatgac gggcgccggg ccaccatctc actgagcgac agtgacctgc 3550

 tgcggctgga gggtgactcg cgtaccgtgc ggctgctgaa ggagctgcgg 3600

 cgggccctgg gccgcatggt ggagcggagc ctgcgcagcg agctggctgc 3650

 acttcccccc agcgtacagg aggagcacgg gcagctgctt gcgctactgg 3700

 cagagctgct gcgaggaccc tgtggcagct ttgatgtgcg caagacagct 3750

 gacgactgag ccctgcttct gctggggctg tgtacagagt gcaaatgttt 3800

 atttaaaata aagttctatt tatcccttgt gaaaaaaaaa aaaaaaaaaa 3850

 a 3851

<210> 5816
<211> 1194
<212> PRT
<213> Homo sapien

<400> 5816
 Met Phe Ser Leu Asp Ser Phe Arg Lys Asp Arg Ala Gln His Arg
   1               5                  10                  15

 Gln Arg Gln Cys Lys Leu Pro Pro Pro Arg Leu Pro Pro Met Cys
                  20                  25                  30

 Val Asn Pro Thr Pro Gly Gly Thr Ile Ser Arg Ala Ser Arg Asp
                  35                  40                  45

 Leu Leu Lys Glu Phe Pro Gln Pro Lys Asn Leu Leu Asn Ser Val
                  50                  55                  60

 Ile Gly Arg Ala Leu Gly Ile Ser His Ala Lys Asp Lys Leu Val
                  65                  70                  75

 Tyr Val His Thr Asn Gly Pro Lys Lys Lys Lys Val Thr Leu His
                  80                  85                  90

 Ile Lys Trp Pro Lys Ser Val Glu Val Glu Gly Tyr Gly Ser Lys
                  95                 100                 105

 Lys Ile Asp Ala Glu Arg Gln Ala Ala Ala Ala Ala Cys Gln Leu
                 110                 115                 120

 Phe Lys Gly Trp Gly Leu Leu Gly Pro Arg Asn Glu Leu Phe Asp
                 125                 130                 135

 Ala Ala Lys Tyr Arg Val Leu Ala Asp Arg Phe Gly Ser Pro Ala
                 140                 145                 150

 Asp Ser Trp Trp Arg Pro Glu Pro Thr Met Pro Pro Thr Ser Trp
                 155                 160                 165

 Arg Gln Leu Asn Pro Glu Ser Ile Arg Pro Gly Gly Pro Gly Gly
                 170                 175                 180

 Leu Ser Arg Ser Leu Gly Arg Glu Glu Glu Glu Asp Glu Glu Glu
                 185                 190                 195

 Glu Leu Glu Glu Gly Thr Ile Asp Val Thr Asp Phe Leu Ser Met
                 200                 205                 210

 Thr Gln Gln Asp Ser His Ala Pro Leu Arg Asp Ser Arg Gly Ser
                 215                 220                 225

 Ser Phe Glu Met Thr Asp Asp Asp Ser Ala Ile Arg Ala Leu Thr
                 230                 235                 240

 Gln Phe Pro Leu Pro Lys Asn Leu Leu Ala Lys Val Ile Gln Ile
                 245                 250                 255

 Ala Thr Ser Ser Ser Thr Ala Lys Asn Leu Met Gln Phe His Thr
                 260                 265                 270

 Val Gly Thr Lys Thr Lys Leu Ser Thr Leu Thr Leu Leu Trp Pro
                 275                 280                 285

 Cys Pro Met Thr Phe Val Ala Lys Gly Arg Arg Lys Ala Glu Ala
                 290                 295                 300

 Glu Asn Lys Ala Ala Ala Leu Ala Cys Lys Lys Leu Lys Ser Leu
                 305                 310                 315

 Gly Leu Val Asp Arg Asn Asn Glu Pro Leu Thr His Ala Met Tyr
                 320                 325                 330

 Asn Leu Ala Ser Leu Arg Glu Leu Gly Glu Thr Gln Arg Arg Pro
                 335                 340                 345

 Cys Thr Ile Gln Val Pro Glu Pro Ile Leu Arg Lys Ile Glu Thr
                 350                 355                 360

 Phe Leu Asn His Tyr Pro Val Glu Ser Ser Trp Ile Ala Pro Glu
                 365                 370                 375

 Leu Arg Leu Gln Ser Asp Asp Ile Leu Pro Leu Gly Lys Asp Ser
                 380                 385                 390

 Gly Pro Leu Ser Asp Pro Ile Thr Gly Lys Pro Tyr Val Pro Leu
                 395                 400                 405

 Leu Glu Ala Glu Glu Val Arg Leu Ser Gln Ser Leu Leu Glu Leu
                 410                 415                 420

 Trp Arg Arg Arg Gly Pro Val Trp Gln Glu Ala Pro Gln Leu Pro
                 425                 430                 435

 Val Asp Pro His Arg Asp Thr Ile Leu Asn Ala Ile Glu Gln His
                 440                 445                 450

 Pro Val Val Val Ile Ser Gly Asp Thr Gly Cys Gly Lys Thr Thr
                 455                 460                 465

 Arg Ile Pro Gln Leu Leu Leu Glu Arg Tyr Val Thr Glu Gly Arg
                 470                 475                 480

 Gly Ala Arg Cys Asn Val Ile Ile Thr Gln Pro Arg Arg Ile Ser
                 485                 490                 495

 Ala Val Ser Val Ala Gln Arg Val Ser His Glu Leu Gly Pro Ser
                 500                 505                 510

 Leu Arg Arg Asn Val Gly Phe Gln Val Arg Leu Glu Ser Lys Pro
                 515                 520                 525

 Pro Ser Arg Gly Gly Ala Leu Leu Phe Cys Thr Val Gly Ile Leu
                 530                 535                 540

 Leu Arg Lys Leu Gln Ser Asn Pro Ser Leu Glu Gly Val Ser His
                 545                 550                 555

 Val Ile Val Asp Glu Val His Glu Arg Asp Val Asn Thr Asp Phe
                 560                 565                 570

 Leu Leu Ile Leu Leu Lys Gly Leu Gln Arg Leu Asn Pro Ala Leu
                 575                 580                 585

 Arg Leu Val Leu Met Ser Ala Thr Gly Asp Asn Glu Arg Phe Ser
                 590                 595                 600

 Arg Tyr Phe Gly Gly Cys Pro Val Ile Lys Val Pro Gly Phe Met
                 605                 610                 615

 Tyr Pro Val Lys Glu His Tyr Leu Glu Asp Ile Leu Ala Lys Leu
                 620                 625                 630

 Gly Lys His Gln Tyr Leu His Arg His Arg His His Glu Ser Glu
                 635                 640                 645

 Asp Glu Cys Ala Leu Asp Leu Asp Leu Val Thr Asp Leu Val Leu
                 650                 655                 660

 His Ile Asp Ala Arg Gly Glu Pro Gly Gly Ile Leu Cys Phe Leu
                 665                 670                 675

 Pro Gly Trp Gln Glu Ile Lys Gly Val Gln Gln Arg Leu Gln Glu
                 680                 685                 690

 Ala Leu Gly Met His Glu Ser Lys Tyr Leu Ile Leu Pro Val His
                 695                 700                 705

 Ser Asn Ile Pro Met Met Asp Gln Lys Ala Ile Phe Gln Gln Pro
                 710                 715                 720

 Pro Val Gly Val Arg Lys Ile Val Leu Ala Thr Asn Ile Ala Glu
                 725                 730                 735

 Thr Ser Ile Thr Ile Asn Asp Ile Val His Val Val Asp Ser Gly
                 740                 745                 750

 Leu His Lys Glu Glu Arg Tyr Asp Leu Lys Thr Lys Val Ser Cys
                 755                 760                 765

 Leu Glu Thr Val Trp Val Ser Arg Ala Asn Val Ile Gln Arg Arg
                 770                 775                 780

 Gly Arg Ala Gly Arg Cys Gln Ser Gly Phe Ala Tyr His Leu Phe
                 785                 790                 795

 Pro Arg Ser Arg Leu Glu Lys Met Val Pro Phe Gln Val Pro Glu
                 800                 805                 810

 Ile Leu Arg Thr Pro Leu Glu Asn Leu Val Leu Gln Ala Lys Ile
                 815                 820                 825

 His Met Pro Glu Lys Thr Ala Val Glu Phe Leu Ser Lys Ala Val
                 830                 835                 840

 Asp Ser Pro Asn Ile Lys Ala Val Asp Glu Ala Val Ile Leu Leu
                 845                 850                 855

 Gln Glu Ile Gly Val Leu Asp Gln Arg Glu Tyr Leu Thr Thr Leu
                 860                 865                 870

 Gly Gln Arg Leu Ala His Ile Ser Thr Asp Pro Arg Leu Ala Lys
                 875                 880                 885

 Ala Ile Val Leu Ala Ala Ile Phe Arg Cys Leu His Pro Leu Leu
                 890                 895                 900

 Val Val Val Ser Cys Leu Thr Arg Asp Pro Phe Ser Ser Ser Leu
                 905                 910                 915

 Gln Asn Arg Ala Glu Val Asp Lys Val Lys Ala Leu Leu Ser His
                 920                 925                 930

 Asp Ser Gly Ser Asp His Leu Ala Phe Val Arg Ala Val Ala Gly
                 935                 940                 945

 Trp Glu Glu Val Leu Arg Trp Gln Asp Arg Ser Ser Arg Glu Asn
                 950                 955                 960

 Tyr Leu Glu Glu Asn Leu Leu Tyr Ala Pro Ser Leu Arg Phe Ile
                 965                 970                 975

 His Gly Leu Ile Lys Gln Phe Ser Glu Asn Ile Tyr Glu Ala Phe
                 980                 985                 990

 Leu Val Gly Lys Pro Ser Asp Cys Thr Leu Ala Ser Ala Gln Cys
                 995                1000                1005

 Asn Glu Tyr Ser Glu Glu Glu Glu Leu Val Lys Gly Val Leu Met
                1010                1015                1020

 Ala Gly Leu Tyr Pro Asn Leu Ile Gln Val Arg Gln Gly Lys Val
                1025                1030                1035

 Thr Arg Gln Gly Lys Phe Lys Pro Asn Ser Val Thr Tyr Arg Thr
                1040                1045                1050

 Lys Ser Gly Asn Ile Leu Leu His Lys Ser Thr Ile Asn Arg Glu
                1055                1060                1065

 Ala Thr Arg Leu Arg Ser Arg Trp Leu Thr Tyr Phe Met Ala Val
                1070                1075                1080

 Lys Ser Asn Gly Ser Val Phe Val Arg Asp Ser Ser Gln Val His
                1085                1090                1095

 Pro Leu Ala Val Leu Leu Leu Thr Asp Gly Asp Val His Ile Arg
                1100                1105                1110

 Asp Asp Gly Arg Arg Ala Thr Ile Ser Leu Ser Asp Ser Asp Leu
                1115                1120                1125

 Leu Arg Leu Glu Gly Asp Ser Arg Thr Val Arg Leu Leu Lys Glu
                1130                1135                1140

 Leu Arg Arg Ala Leu Gly Arg Met Val Glu Arg Ser Leu Arg Ser
                1145                1150                1155

 Glu Leu Ala Ala Leu Pro Pro Ser Val Gln Glu Glu His Gly Gln
                1160                1165                1170

 Leu Leu Ala Leu Leu Ala Glu Leu Leu Arg Gly Pro Cys Gly Ser
                1175                1180                1185

 Phe Asp Val Arg Lys Thr Ala Asp Asp
                1190

<210> 5817
<211> 624
<212> DNA
<213> Homo sapien

<400> 5817
 ggcgggccgc tcccacttcg gcacgagggg cacgaggtaa atcttttctg 50

 cttactgaaa aggaagagtc tgatgattag ttactgatcc tctttgcatt 100

 tgtaaagctt tggagatatt gaatcatgtt accatttctg tttttttcca 150

 ccctgttttc ttccatattt actgaagctc agaagcagta ttgggtctgc 200

 aactcatccg atgcaagtat ttcatacacc tactgtgata aaatgcaata 250

 cccaatttca attaatgtta acccctgtat agaattgaaa ggatccaaag 300

 gattattgca cattttctac attccaagga gagatttaaa gcaattatat 350

 ttcaatctct atataactgt caacaccatg aatcttccaa agcgcaaaga 400

 agttatttgc cgaggatctg atgacgatta ctctttttgc agagctctga 450

 agggagagac tgtgaataca acaatatcat tctccttcaa gggaataaaa 500

 ttttctaagg gaaaatacaa atgtgttgtt gaagctattt ctgggagccc 550

 agaagaaatg ctcttttgct tggagtttgt catcctacac caacctaatt 600

 caaattagaa taaattgagt attt 624

<210> 5818
<211> 160
<212> PRT
<213> Homo sapien

<400> 5818
 Met Leu Pro Phe Leu Phe Phe Ser Thr Leu Phe Ser Ser Ile Phe
   1               5                  10                  15

 Thr Glu Ala Gln Lys Gln Tyr Trp Val Cys Asn Ser Ser Asp Ala
                  20                  25                  30

 Ser Ile Ser Tyr Thr Tyr Cys Asp Lys Met Gln Tyr Pro Ile Ser
                  35                  40                  45

 Ile Asn Val Asn Pro Cys Ile Glu Leu Lys Gly Ser Lys Gly Leu
                  50                  55                  60

 Leu His Ile Phe Tyr Ile Pro Arg Arg Asp Leu Lys Gln Leu Tyr
                  65                  70                  75

 Phe Asn Leu Tyr Ile Thr Val Asn Thr Met Asn Leu Pro Lys Arg
                  80                  85                  90

 Lys Glu Val Ile Cys Arg Gly Ser Asp Asp Asp Tyr Ser Phe Cys
                  95                 100                 105

 Arg Ala Leu Lys Gly Glu Thr Val Asn Thr Thr Ile Ser Phe Ser
                 110                 115                 120

 Phe Lys Gly Ile Lys Phe Ser Lys Gly Lys Tyr Lys Cys Val Val
                 125                 130                 135

 Glu Ala Ile Ser Gly Ser Pro Glu Glu Met Leu Phe Cys Leu Glu
                 140                 145                 150

 Phe Val Ile Leu His Gln Pro Asn Ser Asn
                 155                 160

<210> 5819
<211> 1554
<212> DNA
<213> Homo sapien

<400> 5819
 gcgcgcctcg ccggcgcctc catcccggat ccttgctgca gcgtcagcgc 50

 cgccgcccgt gcctttcctc ttcctcctcc tcctccttgg catccgcctc 100

 ttcttcctcc tgcgtcctcc cccgctgcct ccgctgctcc cgacgcggag 150

 cccggagccc gcgccgagcc cctggcctcg cggtgccatg ctgccccggc 200

 ggcggcgctg aaggatggcg acgccgctgc ctccgccctc cccgcggcac 250

 ctgcggctgc tgcggctgct gctctccggc ctcgtcctcg gcgccgccct 300

 gcgtggagcc gccgccggcc acccggatgt agccgcctgt cccgggagcc 350

 tggactgtgc cctgaagagg cgggcaaggt gtcctcctgg tgcacatgcc 400

 tgtgggccct gccttcagcc cttccaggag gaccagcaag ggctctgtgt 450

 gcccaggatg cgccggcctc caggcggggg ccggccccag cccagactgg 500

 aagatgagat tgacttcctg gcccaggagc ttgcccggaa ggagtctgga 550

 cactcaactc cgcccctacc caaggaccga cagcggctcc cggagcctgc 600

 caccctgggc ttctcggcac gggggcaggg gctggagctg ggcctcccct 650

 ccactccagg aacccccacg cccacgcccc acacctccat gggctcccct 700

 gtgtcatccg acccggtgca catgtcgccc ctggagcccc ggggagggca 750

 aggcgacggc ctcgcccttg tgctgatcct ggcgttctgt gtggccggtg 800

 cagccgccct ctccgtagcc tccctctgct ggtgcaggct gcatcgtgag 850

 atccgcctga ctcagaaggc cgactacgcc actgcgaagg cccctggctc 900

 acctgcagct ccccggatct cgcctgggga ccaacggctg gcacagagcg 950

 cggagatgta ccactaccag caccaacggc aacagatgct gtgcctggag 1000

 cggcataaag agccacccaa ggagctggac acggcctcct cggatgagga 1050

 gaatgaggac ggagacttca cggtgtacga gtgcccgggc ctggccccga 1100

 ccggggaaat ggaggtgcgc aaccctctgt tcgaccacgc cgcactgtcc 1150

 gcgcccctgc cggcccccag ctcaccgcct gcactgccat gacctggagg 1200

 cagacagacg cccacctgct ccccgacctc gaggcccccg gggaggggca 1250

 gggcctggag cttcccacta aaaacatgtt ttgatgctgt gtgcttttgg 1300

 ctgggcctcg ggctccaggc cctgggaccc cttgccaggg agacccccga 1350

 acctttgtgc caggacacct cctggtcccc tgcacctctc ctgttcggtt 1400

 tagaccccca aactggaggg ggcatggaga accgtagagc gcaggaacgg 1450

 gtgggtaatt ctagagacaa aagccaatta aagtccattt cagaaaaaaa 1500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1550

 aaaa 1554

<210> 5820
<211> 325
<212> PRT
<213> Homo sapien

<400> 5820
 Met Ala Thr Pro Leu Pro Pro Pro Ser Pro Arg His Leu Arg Leu
   1               5                  10                  15

 Leu Arg Leu Leu Leu Ser Gly Leu Val Leu Gly Ala Ala Leu Arg
                  20                  25                  30

 Gly Ala Ala Ala Gly His Pro Asp Val Ala Ala Cys Pro Gly Ser
                  35                  40                  45

 Leu Asp Cys Ala Leu Lys Arg Arg Ala Arg Cys Pro Pro Gly Ala
                  50                  55                  60

 His Ala Cys Gly Pro Cys Leu Gln Pro Phe Gln Glu Asp Gln Gln
                  65                  70                  75

 Gly Leu Cys Val Pro Arg Met Arg Arg Pro Pro Gly Gly Gly Arg
                  80                  85                  90

 Pro Gln Pro Arg Leu Glu Asp Glu Ile Asp Phe Leu Ala Gln Glu
                  95                 100                 105

 Leu Ala Arg Lys Glu Ser Gly His Ser Thr Pro Pro Leu Pro Lys
                 110                 115                 120

 Asp Arg Gln Arg Leu Pro Glu Pro Ala Thr Leu Gly Phe Ser Ala
                 125                 130                 135

 Arg Gly Gln Gly Leu Glu Leu Gly Leu Pro Ser Thr Pro Gly Thr
                 140                 145                 150

 Pro Thr Pro Thr Pro His Thr Ser Met Gly Ser Pro Val Ser Ser
                 155                 160                 165

 Asp Pro Val His Met Ser Pro Leu Glu Pro Arg Gly Gly Gln Gly
                 170                 175                 180

 Asp Gly Leu Ala Leu Val Leu Ile Leu Ala Phe Cys Val Ala Gly
                 185                 190                 195

 Ala Ala Ala Leu Ser Val Ala Ser Leu Cys Trp Cys Arg Leu His
                 200                 205                 210

 Arg Glu Ile Arg Leu Thr Gln Lys Ala Asp Tyr Ala Thr Ala Lys
                 215                 220                 225

 Ala Pro Gly Ser Pro Ala Ala Pro Arg Ile Ser Pro Gly Asp Gln
                 230                 235                 240

 Arg Leu Ala Gln Ser Ala Glu Met Tyr His Tyr Gln His Gln Arg
                 245                 250                 255

 Gln Gln Met Leu Cys Leu Glu Arg His Lys Glu Pro Pro Lys Glu
                 260                 265                 270

 Leu Asp Thr Ala Ser Ser Asp Glu Glu Asn Glu Asp Gly Asp Phe
                 275                 280                 285

 Thr Val Tyr Glu Cys Pro Gly Leu Ala Pro Thr Gly Glu Met Glu
                 290                 295                 300

 Val Arg Asn Pro Leu Phe Asp His Ala Ala Leu Ser Ala Pro Leu
                 305                 310                 315

 Pro Ala Pro Ser Ser Pro Pro Ala Leu Pro
                 320                 325

<210> 5821
<211> 1669
<212> DNA
<213> Homo sapien

<400> 5821
 ggggcgagac ctacgacgcc ggcgagcagt ggccgttacg cctaaaaaga 50

 tggcggtctt ggcacctcta attgctctcg tgtattcggt gccgcgactt 100

 tcacgatggc tcgcccaacc ttactacctt ctgtcggccc tgctctctgc 150

 tgccttccta ctcgtgagga aactgccgcc gctctgccac ggtctgccca 200

 cccaacgcga agacggtaac ccgtgtgact ttgactggag agaagtggag 250

 atcctgatgt ttctcagtgc cattgtgatg atgaagaacc gcagatccat 300

 cactgtggag caacatatag gcaacatttt catgtttagt aaagtggcca 350

 acacaattct tttcttccgc ttggatattc gcatgggcct actttacatc 400

 acactctgca tagtgttcct gatgacgtgc aaaccccccc tatatatggg 450

 ccctgagtat atcaagtact tcaatgataa aaccattgat gaggaactag 500

 aacgggacaa gagggtcact tggattgtgg agttctttgc caattggtct 550

 aatgactgcc aatcatttgc ccctatctat gctgacctct cccttaaata 600

 caactgtaca gggctaaatt ttgggaaggt ggatgttgga cgctatactg 650

 atgttagtac gcggtacaaa gtgagcacat cacccctcac caagcaactc 700

 cctaccctga tcctgttcca aggtggcaag gaggcaatgc ggcggccaca 750

 gattgacaag aaaggacggg ctgtctcatg gaccttctct gaggagaatg 800

 tgatccgaga atttaactta aatgagctat accagcgggc caagaaacta 850

 tcaaaggctg gagacaatat ccctgaggag cagcctgtgg cttcaacccc 900

 caccacagtg tcagatgggg aaaacaagaa ggataaataa gatcctcact 950

 ttggcagtgc ttcctctcct gtcaattcca ggctctttcc ataaccacaa 1000

 gcctgaggtg cagcttttat ttatgttttc cctttggctg tgactgggtg 1050

 gggcagcatg cagcttctga ttttaaagag gcatctaggg aattgtcagg 1100

 caccctacag gaaggcctgc catgcttgtg gccaactgtt tcactggagc 1150

 aaagaaagag atctcatagg acggaggggg aaaatggttt tccctccaag 1200

 cttgggtcag tgtgttaact gcttatcagc tattcagaca tctccatggt 1250

 ttctccatga aactctgtgg tttcatcatt ccttcttagt tgacctgcac 1300

 agcttggtta gacctagatt taaccctaag gtaagatgct ggggtataga 1350

 acgctaagaa ttttccccca aggactcttg cttcctcaag cccttctggc 1400

 ttcgtttatg gtcttcatta aaagtataag cctaactttg tcgctagtcc 1450

 taaggagaaa cctttaacca caaagttttt atcattgaag acaatattga 1500

 acaaccccct attttgtggg gattgagaag gggtgaatag aggcttgaga 1550

 ctttcctttg tgtggtagga cttggaggag aaatcccctg gactttcact 1600

 aaccctctga catactcccc acacccagtt gatggctttc cgtaataaaa 1650

 agattgggat ttccttttg 1669

<210> 5822
<211> 296
<212> PRT
<213> Homo sapien

<400> 5822
 Met Ala Val Leu Ala Pro Leu Ile Ala Leu Val Tyr Ser Val Pro
   1               5                  10                  15

 Arg Leu Ser Arg Trp Leu Ala Gln Pro Tyr Tyr Leu Leu Ser Ala
                  20                  25                  30

 Leu Leu Ser Ala Ala Phe Leu Leu Val Arg Lys Leu Pro Pro Leu
                  35                  40                  45

 Cys His Gly Leu Pro Thr Gln Arg Glu Asp Gly Asn Pro Cys Asp
                  50                  55                  60

 Phe Asp Trp Arg Glu Val Glu Ile Leu Met Phe Leu Ser Ala Ile
                  65                  70                  75

 Val Met Met Lys Asn Arg Arg Ser Ile Thr Val Glu Gln His Ile
                  80                  85                  90

 Gly Asn Ile Phe Met Phe Ser Lys Val Ala Asn Thr Ile Leu Phe
                  95                 100                 105

 Phe Arg Leu Asp Ile Arg Met Gly Leu Leu Tyr Ile Thr Leu Cys
                 110                 115                 120

 Ile Val Phe Leu Met Thr Cys Lys Pro Pro Leu Tyr Met Gly Pro
                 125                 130                 135

 Glu Tyr Ile Lys Tyr Phe Asn Asp Lys Thr Ile Asp Glu Glu Leu
                 140                 145                 150

 Glu Arg Asp Lys Arg Val Thr Trp Ile Val Glu Phe Phe Ala Asn
                 155                 160                 165

 Trp Ser Asn Asp Cys Gln Ser Phe Ala Pro Ile Tyr Ala Asp Leu
                 170                 175                 180

 Ser Leu Lys Tyr Asn Cys Thr Gly Leu Asn Phe Gly Lys Val Asp
                 185                 190                 195

 Val Gly Arg Tyr Thr Asp Val Ser Thr Arg Tyr Lys Val Ser Thr
                 200                 205                 210

 Ser Pro Leu Thr Lys Gln Leu Pro Thr Leu Ile Leu Phe Gln Gly
                 215                 220                 225

 Gly Lys Glu Ala Met Arg Arg Pro Gln Ile Asp Lys Lys Gly Arg
                 230                 235                 240

 Ala Val Ser Trp Thr Phe Ser Glu Glu Asn Val Ile Arg Glu Phe
                 245                 250                 255

 Asn Leu Asn Glu Leu Tyr Gln Arg Ala Lys Lys Leu Ser Lys Ala
                 260                 265                 270

 Gly Asp Asn Ile Pro Glu Glu Gln Pro Val Ala Ser Thr Pro Thr
                 275                 280                 285

 Thr Val Ser Asp Gly Glu Asn Lys Lys Asp Lys
                 290                 295

<210> 5823
<211> 3094
<212> DNA
<213> Homo sapien

<400> 5823
 gtctcggcca tgacacacat ttgacatgcc ctccctcaac ctacttatag 50

 actatttttc ttgctctgca gcatggacca aagagaaatt ctgcagaagt 100

 tcctggatga ggcccaaagc aagaaaatta ctaaagagga gtttgccaat 150

 gaatttctga agctgaaaag gcaatctacc aagtacaagg cagacaaaac 200

 ctatcctaca actgtggctg agaagcccaa gaatatcaag aaaaacagat 250

 ataaggatat tttgccctat gattatagcc gggtagaact atccctgata 300

 acctctgatg aggattccag ctacatcaat gccaacttca ttaagggagt 350

 ttatggaccc aaggcttata ttgccaccca gggtccttta tctacaaccc 400

 tcctggactt ctggaggatg atttgggaat atagtgtcct tatcattggt 450

 atggcatgca tggagtatga aatgggaaag aaaaagtgtg agcgctactg 500

 ggctgagcca gtagagatgc agctggaatt tggccctttc tctgtatcct 550

 gtgaagctga aaaaaggaaa tctgattata taatcaggac tctaaaagtt 600

 aagttcaata gtgaaactcg aactatctac cagtttcatt acaagaattg 650

 gccagaccat gatgtacctt catctataga ccctattctt gagctcatct 700

 gggatgtacg ttgttaccaa gaggatgaca gtgttcccat atgcattcac 750

 tgcagtgctg gctgtggaag gactggtgtt atttgtgcta ttgattatac 800

 atggatgttg ctaaaagatg ggataattcc tgagaacttc agtgttttca 850

 gtttgatccg ggaaatgcgg acacagaggc cttcattagt tcaaacgcag 900

 gaacaatatg aactggtcta caatgctgta ttagaactat ttaagagaca 950

 gatggatgtt atcagagata aacattctgg aacagagagt caagcaaagc 1000

 attgtattcc tgagaaaaat cacactctcc aagcagactc ttattctcct 1050

 aatttaccaa aaagtaccac aaaagcagca aaaatgatga accaacaaag 1100

 gacaaaaatg gaaatcaaag aatcttcttc ctttgacttt aggacttctg 1150

 aaataagtgc aaaagaagag ctagttttgc accctgctaa atcaagcact 1200

 tcttttgact ttctggagct aaattacagt tttgacaaaa atgctgacac 1250

 aaccatgaaa tggcagacaa aggcatttcc aatagttggg gagcctcttc 1300

 agaagcatca aagtttggat ttgggctctc ctttgtttga gggatgttct 1350

 aattctaaac ctgtaaatgc agcaggaaga tattttaatt caaaggtgcc 1400

 aataacacgg accaaatcaa ctccttttga attgatacag cagagagaaa 1450

 ccaaggaggt ggacagcaag gaaaactttt cttatttgga atctcaacca 1500

 catgattctt gttttgtaga gatgcaggct caaaaagtaa tgcatgtttc 1550

 ttcagcagaa ctgaattatt cactgccata tgactctaaa caccaaatac 1600

 gtaatgcctc taatgtaaag caccatgact ctagtgctct tggtgtatat 1650

 tcttacatac ctttagtgga aaatccttat ttttcatcat ggcctccaag 1700

 tggtaccagt tctaagatgt ctcttgattt acctgagaag caagatggaa 1750

 ctgtttttcc ttcttctctg ttgccaacat cctctacatc cctcttctct 1800

 tattacaatt cacatgattc tttatcactg aattctccaa ccaatatttc 1850

 ctcactattg aaccaggagt cagctgtact agcaactgct ccaaggatag 1900

 atgatgaaat cccccctcca cttcctgtat ggacacctga atcatttatt 1950

 gtggttgagg aagctggaga attctcacca aatgttccca aatccttatc 2000

 ctcagctgtg aaggtaaaaa ttggaacatc actggaatgg ggtggaacat 2050

 ctgaaccaaa gaaatttgat gactctgtga tacttagacc aagcaagagt 2100

 gtaaaactcc gaagtcctaa atcagaacta catcaagatc gttcttctcc 2150

 cccacctcct ctcccagaaa gaactctaga gtccttcttt cttgccgatg 2200

 aagattgtat gcaggcccaa tctatagaaa catattctac tagctatcct 2250

 gacaccatgg aaaattcaac atcttcaaaa cagacactga agacttctgg 2300

 aaaaagtttc acaaggagta agagtttgaa aattttgcga aacatgaaaa 2350

 agagtatctg taattcttgc ccaccaaaca agcctgcaga atctgttcag 2400

 tcaaataact ccagctcatt tctgaatttt ggttttgcaa accgtttttc 2450

 aaaacccaaa ggaccaagga atccaccacc aacttggaat atttaataaa 2500

 actccagatt tataataata tgggctgcaa gtacacctgc aaataaaact 2550

 actagaatac tgctagttaa aataagtgct ctatatgcat aatatcaaat 2600

 atgaagatat gctaatgtgt taatagcttt taaaagaaaa gcaaaatgcc 2650

 aataagtgcc agttttgcat tttcatatca tttgcattga gttgaaaact 2700

 gcaaataaaa gtttgtcact tgagcttatg tacagaatgc tatatgagaa 2750

 acacttttag aatggattta tttttcattt ttgccagtta tttttattgt 2800

 cttttacttt tctacataaa cataaacttc aaaaggtttg taagatttgg 2850

 atctcaacta atttctacat tgccagaata tactataaaa agttaaaaaa 2900

 aaaaacttac tttgtgggtt gcaatacaaa ctgctcttga caatgactat 2950

 tccctgacag ttatttttgc ctaaatggag tataccttgt aaatcttccc 3000

 aaatgttgtg gaaaactgga atattaagaa aatgagaaat tatatttatt 3050

 agaataaaat gtgcaaataa tgacaattat ttgaatgtaa caag 3094

<210> 5824
<211> 807
<212> PRT
<213> Homo sapien

<400> 5824
 Met Asp Gln Arg Glu Ile Leu Gln Lys Phe Leu Asp Glu Ala Gln
   1               5                  10                  15

 Ser Lys Lys Ile Thr Lys Glu Glu Phe Ala Asn Glu Phe Leu Lys
                  20                  25                  30

 Leu Lys Arg Gln Ser Thr Lys Tyr Lys Ala Asp Lys Thr Tyr Pro
                  35                  40                  45

 Thr Thr Val Ala Glu Lys Pro Lys Asn Ile Lys Lys Asn Arg Tyr
                  50                  55                  60

 Lys Asp Ile Leu Pro Tyr Asp Tyr Ser Arg Val Glu Leu Ser Leu
                  65                  70                  75

 Ile Thr Ser Asp Glu Asp Ser Ser Tyr Ile Asn Ala Asn Phe Ile
                  80                  85                  90

 Lys Gly Val Tyr Gly Pro Lys Ala Tyr Ile Ala Thr Gln Gly Pro
                  95                 100                 105

 Leu Ser Thr Thr Leu Leu Asp Phe Trp Arg Met Ile Trp Glu Tyr
                 110                 115                 120

 Ser Val Leu Ile Ile Gly Met Ala Cys Met Glu Tyr Glu Met Gly
                 125                 130                 135

 Lys Lys Lys Cys Glu Arg Tyr Trp Ala Glu Pro Val Glu Met Gln
                 140                 145                 150

 Leu Glu Phe Gly Pro Phe Ser Val Ser Cys Glu Ala Glu Lys Arg
                 155                 160                 165

 Lys Ser Asp Tyr Ile Ile Arg Thr Leu Lys Val Lys Phe Asn Ser
                 170                 175                 180

 Glu Thr Arg Thr Ile Tyr Gln Phe His Tyr Lys Asn Trp Pro Asp
                 185                 190                 195

 His Asp Val Pro Ser Ser Ile Asp Pro Ile Leu Glu Leu Ile Trp
                 200                 205                 210

 Asp Val Arg Cys Tyr Gln Glu Asp Asp Ser Val Pro Ile Cys Ile
                 215                 220                 225

 His Cys Ser Ala Gly Cys Gly Arg Thr Gly Val Ile Cys Ala Ile
                 230                 235                 240

 Asp Tyr Thr Trp Met Leu Leu Lys Asp Gly Ile Ile Pro Glu Asn
                 245                 250                 255

 Phe Ser Val Phe Ser Leu Ile Arg Glu Met Arg Thr Gln Arg Pro
                 260                 265                 270

 Ser Leu Val Gln Thr Gln Glu Gln Tyr Glu Leu Val Tyr Asn Ala
                 275                 280                 285

 Val Leu Glu Leu Phe Lys Arg Gln Met Asp Val Ile Arg Asp Lys
                 290                 295                 300

 His Ser Gly Thr Glu Ser Gln Ala Lys His Cys Ile Pro Glu Lys
                 305                 310                 315

 Asn His Thr Leu Gln Ala Asp Ser Tyr Ser Pro Asn Leu Pro Lys
                 320                 325                 330

 Ser Thr Thr Lys Ala Ala Lys Met Met Asn Gln Gln Arg Thr Lys
                 335                 340                 345

 Met Glu Ile Lys Glu Ser Ser Ser Phe Asp Phe Arg Thr Ser Glu
                 350                 355                 360

 Ile Ser Ala Lys Glu Glu Leu Val Leu His Pro Ala Lys Ser Ser
                 365                 370                 375

 Thr Ser Phe Asp Phe Leu Glu Leu Asn Tyr Ser Phe Asp Lys Asn
                 380                 385                 390

 Ala Asp Thr Thr Met Lys Trp Gln Thr Lys Ala Phe Pro Ile Val
                 395                 400                 405

 Gly Glu Pro Leu Gln Lys His Gln Ser Leu Asp Leu Gly Ser Pro
                 410                 415                 420

 Leu Phe Glu Gly Cys Ser Asn Ser Lys Pro Val Asn Ala Ala Gly
                 425                 430                 435

 Arg Tyr Phe Asn Ser Lys Val Pro Ile Thr Arg Thr Lys Ser Thr
                 440                 445                 450

 Pro Phe Glu Leu Ile Gln Gln Arg Glu Thr Lys Glu Val Asp Ser
                 455                 460                 465

 Lys Glu Asn Phe Ser Tyr Leu Glu Ser Gln Pro His Asp Ser Cys
                 470                 475                 480

 Phe Val Glu Met Gln Ala Gln Lys Val Met His Val Ser Ser Ala
                 485                 490                 495

 Glu Leu Asn Tyr Ser Leu Pro Tyr Asp Ser Lys His Gln Ile Arg
                 500                 505                 510

 Asn Ala Ser Asn Val Lys His His Asp Ser Ser Ala Leu Gly Val
                 515                 520                 525

 Tyr Ser Tyr Ile Pro Leu Val Glu Asn Pro Tyr Phe Ser Ser Trp
                 530                 535                 540

 Pro Pro Ser Gly Thr Ser Ser Lys Met Ser Leu Asp Leu Pro Glu
                 545                 550                 555

 Lys Gln Asp Gly Thr Val Phe Pro Ser Ser Leu Leu Pro Thr Ser
                 560                 565                 570

 Ser Thr Ser Leu Phe Ser Tyr Tyr Asn Ser His Asp Ser Leu Ser
                 575                 580                 585

 Leu Asn Ser Pro Thr Asn Ile Ser Ser Leu Leu Asn Gln Glu Ser
                 590                 595                 600

 Ala Val Leu Ala Thr Ala Pro Arg Ile Asp Asp Glu Ile Pro Pro
                 605                 610                 615

 Pro Leu Pro Val Trp Thr Pro Glu Ser Phe Ile Val Val Glu Glu
                 620                 625                 630

 Ala Gly Glu Phe Ser Pro Asn Val Pro Lys Ser Leu Ser Ser Ala
                 635                 640                 645

 Val Lys Val Lys Ile Gly Thr Ser Leu Glu Trp Gly Gly Thr Ser
                 650                 655                 660

 Glu Pro Lys Lys Phe Asp Asp Ser Val Ile Leu Arg Pro Ser Lys
                 665                 670                 675

 Ser Val Lys Leu Arg Ser Pro Lys Ser Glu Leu His Gln Asp Arg
                 680                 685                 690

 Ser Ser Pro Pro Pro Pro Leu Pro Glu Arg Thr Leu Glu Ser Phe
                 695                 700                 705

 Phe Leu Ala Asp Glu Asp Cys Met Gln Ala Gln Ser Ile Glu Thr
                 710                 715                 720

 Tyr Ser Thr Ser Tyr Pro Asp Thr Met Glu Asn Ser Thr Ser Ser
                 725                 730                 735

 Lys Gln Thr Leu Lys Thr Ser Gly Lys Ser Phe Thr Arg Ser Lys
                 740                 745                 750

 Ser Leu Lys Ile Leu Arg Asn Met Lys Lys Ser Ile Cys Asn Ser
                 755                 760                 765

 Cys Pro Pro Asn Lys Pro Ala Glu Ser Val Gln Ser Asn Asn Ser
                 770                 775                 780

 Ser Ser Phe Leu Asn Phe Gly Phe Ala Asn Arg Phe Ser Lys Pro
                 785                 790                 795

 Lys Gly Pro Arg Asn Pro Pro Pro Thr Trp Asn Ile
                 800                 805

<210> 5825
<211> 3865
<212> DNA
<213> Homo sapien

<400> 5825
 ctattattct tttactattt tttctattac cattttttct agtaccattt 50

 tttctattat tcttttacta taattgtata taatatggca gctgcttgcc 100

 acatgtacta tgtggagaga tgtaccaccc tgcatcagct tttaccctac 150

 agaaggaaat cagcgttcca ttatatttta ttgttatcaa cagtttagga 200

 atacatagct ttgcttttgc ctttttcttt ccttcccctt gtttcccctc 250

 gcctcagaga aaagaaggaa aaaaaaattc atctttccta cccccctctt 300

 tttggatgat aggacttgaa gacaatctga aataccacat aaactcactt 350

 ccagatgttt tttgtttcat atgcaattga attgggctca gactgtgttt 400

 ttaagctgta tggtaaaaat atcactgtct tctagggcct tattgggggg 450

 cagggagaga cgtgacactt tgtcagaagg gattgagtct gctaacttaa 500

 actctccttg attcaggaat acaaagtctc cagctgtgaa cagagactca 550

 tcagtgaaat agagtacagg ctagaaaggt ctcctatgga tgaactcatg 600

 gtgatgaacg ttcacgtacg gcagatgctg cctcgtggaa aactggaatg 650

 gcaccattct ttgagatgaa gctgaaacat tacaagatct ttgagggaat 700

 gccagtaact ttcacatgta gagtggctgg aaatccaaag ccaaagatct 750

 attggtttaa agatgggaag cagatctctc caaagagtga tcactacacc 800

 attcaaagag atctcgatgg gacctgctcc ctccatacca cagcctccac 850

 cctagatgat gatgggaatt atacaattat ggctgcaaac cctcagggcc 900

 gcatcagttg tactggacgg ctaatggtac aggctgtcaa ccaaagaggt 950

 cgaagtcccc ggtctccctc aggccatcct catgtcagaa ggcctcgttc 1000

 tagatcaagg gacagtggag acgaaaatga accaattcag gagcgattct 1050

 tcagacctca cttcttgcag gctcctggag atctgactgt tcaagaagga 1100

 aaactctgca gaatggactg caaagtcagt gggttaccaa ccccagatct 1150

 aagctggcaa ctagatggaa agcccgtacg ccctgacagt gctcacaaga 1200

 tgctggtgcg tgagaacggg gtgcactctc tgatcataga gccagtcacg 1250

 tcacgtgatg ccggcatcta cacatgtata gctaccaacc gagcaggaca 1300

 gaactcattc agcctggagc ttgtggttgc tgctaaagaa gcacacaaac 1350

 cccctgtgtt tattgagaag ctccaaaaca caggagttgc tgatgggtac 1400

 ccagtgcggc tggaatgtcg tgtattggga gtgccaccac ctcagatatt 1450

 ttggaagaaa gaaaatgaat cactcactca cagcactgac cgagtgagca 1500

 tgcaccagga caaccacggc tacatctgcc tgctcattca gggagccaca 1550

 aaagaagatg ctgggtggta tactgtgtca gccaagaatg aagcagggat 1600

 tgtgtcctgt actgccaggc tggacgttta cacccagtgg catcagcagt 1650

 cacagagcac caagccaaaa aaagtacggc cctcagccag tcgctatgca 1700

 gcactttcgg accagggact agacatcaaa gcagcgttcc aacctgaggc 1750

 caacccatct cacctgacac tgaatactgc cttggtagaa agtgaggacc 1800

 tgtaatccag cattcttgtt aaagctgaaa cactgaaaca gccattgcct 1850

 tgaccaacat attcctttgt cacattatgt aaaaggcaga aacatacctt 1900

 tgactataag aaattaaaaa aaaacaccaa aataatattt ttcttacttg 1950

 atataccaaa cttagtttaa gtagataatg ctaatacaaa tatacacatt 2000

 gcacagaaaa tacacattta ctgtccaatt taaaactttg gaattgctgt 2050

 gattaaagtg atcaaaatgc caaaatacta aaggaaatca attgttcaca 2100

 ggtaactaca atttgtatta tctacaagtg cctttaaaca caagatatag 2150

 gtgctgtgta gcctgatagt gtgaaatgtt taatgaggga gttgtaccac 2200

 aaacagtact acaatgattc tgaagcacag tgtattcaga cagatacagt 2250

 gaaccaagtg caatatgtaa ggatgaaaga agaagagatg acaaagaaat 2300

 ccaagtaaat gccttgtctt tgcaaatgtt tttatattaa atcataagga 2350

 aggaactact tgccttaaat gttaatatca aaagagtttt ctaacaaggt 2400

 taatacctta gttcttaaca ttttttttct ttatgtgtag tgttttcatg 2450

 ctaccttggt aggaaactta tttacaaacc atattaaaag gctaatttaa 2500

 atataaataa tataaagtgc tctgaataaa gcagaaatat attacagttc 2550

 attccacaga aagcatccaa accacccaaa tgaccaaggc atatatagta 2600

 tttggaggaa tcaggggttt ggaaggagta gggaggagaa tgaaggaaaa 2650

 tgcaaccagc atgattatag tgtgttcatt tagataaaag tagaaggcac 2700

 aggagaggta gcaaaggcca ggcttttctt tggttttctt caaacatagg 2750

 tgaaaaaaac actgccattc acaagtcaag gaacccaggg ccagctggaa 2800

 gtgtggagca cacatgctgt ggagcacaca tgctgtggag attgcagtgt 2850

 gtctgaggtt tgtgtagtag tggaagattt taggtatgta gagcaagttg 2900

 aaaatggatt gagactgcat ggtggcataa atgagaaatt gcctgtagca 2950

 tctagtctac ttgaaggaag tggagacata aggagagaca aaaacaggtt 3000

 tgtgccataa agtatttttt caaagacacc aagatgtggt aaatgaaaat 3050

 tattagttca cttccctgct gccatgaaac tttgccttaa gaaggtgctg 3100

 gattccaagg tttgtaaagg catctcggta aagactgctt tttgaatgca 3150

 tatgattttg catcagctag actgagttga ttctgaccag acttgatggt 3200

 tttaagtcgg aaccgataaa ttttaaaaag gagaaaaaat aatttgacct 3250

 agtagtataa aacatgaggc tttaatggta ctttgctatg aaaagaaaac 3300

 actgtattcc ttatgcaaaa cacatgtatc tttcattatt tataagtggc 3350

 ctctcttagc tcagttactc aattcatacg tagtattttt taaaataatt 3400

 ttatatctgt gtaccacccc atatatttca tattactgtt tcacatgtac 3450

 agctttctac ttctttgtaa gaacaccaac caaccaaggt ttaagtgatt 3500

 aataggcttg agcaccgggt ggcagatgtt ctatgcagtg tggttcaagt 3550

 ttctttgacc gcacttatat gcattgctaa tatggaattt aagataccat 3600

 acacagtctc tcatggacct atctctattg tagaattatg acttatgtct 3650

 tacttggcaa atttttctga atgtgacctt tttttgctga tttgctgggt 3700

 ttgggattaa ctagcattat tttgccacct ttatattgta tttataaaaa 3750

 aaaagtacta tcaatcaatc atactacttt ggattgttgt gctggtgtaa 3800

 tgtggattta acatcaataa atatttgaca aataaaaaaa aaaaaaaaaa 3850

 aaaaaaaaaa aaaaa 3865

<210> 5826
<211> 385
<212> PRT
<213> Homo sapien

<400> 5826
 Met Ala Pro Phe Phe Glu Met Lys Leu Lys His Tyr Lys Ile Phe
   1               5                  10                  15

 Glu Gly Met Pro Val Thr Phe Thr Cys Arg Val Ala Gly Asn Pro
                  20                  25                  30

 Lys Pro Lys Ile Tyr Trp Phe Lys Asp Gly Lys Gln Ile Ser Pro
                  35                  40                  45

 Lys Ser Asp His Tyr Thr Ile Gln Arg Asp Leu Asp Gly Thr Cys
                  50                  55                  60

 Ser Leu His Thr Thr Ala Ser Thr Leu Asp Asp Asp Gly Asn Tyr
                  65                  70                  75

 Thr Ile Met Ala Ala Asn Pro Gln Gly Arg Ile Ser Cys Thr Gly
                  80                  85                  90

 Arg Leu Met Val Gln Ala Val Asn Gln Arg Gly Arg Ser Pro Arg
                  95                 100                 105

 Ser Pro Ser Gly His Pro His Val Arg Arg Pro Arg Ser Arg Ser
                 110                 115                 120

 Arg Asp Ser Gly Asp Glu Asn Glu Pro Ile Gln Glu Arg Phe Phe
                 125                 130                 135

 Arg Pro His Phe Leu Gln Ala Pro Gly Asp Leu Thr Val Gln Glu
                 140                 145                 150

 Gly Lys Leu Cys Arg Met Asp Cys Lys Val Ser Gly Leu Pro Thr
                 155                 160                 165

 Pro Asp Leu Ser Trp Gln Leu Asp Gly Lys Pro Val Arg Pro Asp
                 170                 175                 180

 Ser Ala His Lys Met Leu Val Arg Glu Asn Gly Val His Ser Leu
                 185                 190                 195

 Ile Ile Glu Pro Val Thr Ser Arg Asp Ala Gly Ile Tyr Thr Cys
                 200                 205                 210

 Ile Ala Thr Asn Arg Ala Gly Gln Asn Ser Phe Ser Leu Glu Leu
                 215                 220                 225

 Val Val Ala Ala Lys Glu Ala His Lys Pro Pro Val Phe Ile Glu
                 230                 235                 240

 Lys Leu Gln Asn Thr Gly Val Ala Asp Gly Tyr Pro Val Arg Leu
                 245                 250                 255

 Glu Cys Arg Val Leu Gly Val Pro Pro Pro Gln Ile Phe Trp Lys
                 260                 265                 270

 Lys Glu Asn Glu Ser Leu Thr His Ser Thr Asp Arg Val Ser Met
                 275                 280                 285

 His Gln Asp Asn His Gly Tyr Ile Cys Leu Leu Ile Gln Gly Ala
                 290                 295                 300

 Thr Lys Glu Asp Ala Gly Trp Tyr Thr Val Ser Ala Lys Asn Glu
                 305                 310                 315

 Ala Gly Ile Val Ser Cys Thr Ala Arg Leu Asp Val Tyr Thr Gln
                 320                 325                 330

 Trp His Gln Gln Ser Gln Ser Thr Lys Pro Lys Lys Val Arg Pro
                 335                 340                 345

 Ser Ala Ser Arg Tyr Ala Ala Leu Ser Asp Gln Gly Leu Asp Ile
                 350                 355                 360

 Lys Ala Ala Phe Gln Pro Glu Ala Asn Pro Ser His Leu Thr Leu
                 365                 370                 375

 Asn Thr Ala Leu Val Glu Ser Glu Asp Leu
                 380                 385

<210> 5827
<211> 1760
<212> DNA
<213> Homo sapien

<400> 5827
 gaattccgag ctttttattc ctaagaggag aaaatcagta acgggagaag 50

 caggaggatg tccagaagaa atttcatccc ttgctctcgc ccctactctt 100

 tctggtgtta gatcgagcta ccctctaaaa gcagtttaga gtggtaaaaa 150

 aaaaaaaaac acaccaaacg ctcgcagcca caaaagggat gaaatttctt 200

 ctggacatcc tcctgcttct cccgttactg atcgtctgct ccctagagtc 250

 cttcgtgaag ctttttattc ctaagaggag aaaatcagtc accggcgaaa 300

 tcgtgctgat tacaggagct gggcatggaa ttgggagact gactgcctat 350

 gaatttgcta aacttaaaag caagctggtt ctctgggata taaataagca 400

 tggactggag gaaacagctg ccaaatgcaa gggactgggt gccaaggttc 450

 atacctttgt ggtagactgc agcaaccgag aagatattta cagctctgca 500

 aagaaggtga aggcagaaat tggagatgtt agtattttag taaataatgc 550

 tggtgtagtc tatacatcag atttgtttgc tacacaagat cctcagattg 600

 aaaagacttt tgaagttaat gtacttgcac atttctggac tacaaaggca 650

 tttcttcctg caatgacgaa gaataaccat ggccatattg tcactgtggc 700

 ttcggcagct ggacatgtct cggtcccctt cttactggct tactgttcaa 750

 gcaagtttgc tgctgttgga tttcataaaa ctttgacaga tgaactggct 800

 gccttacaaa taactggagt caaaacaaca tgtctgtgtc ctaatttcgt 850

 aaacactggc ttcatcaaaa atccaagtac aagtttggga cccactctgg 900

 aacccgagga agtggtaaac aggctgatgc atgggattct gactgagcag 950

 aagatgattt ttattccatc ttctatagct tttttaacaa cattggaaag 1000

 gatccttcct gagcgtttcc tggcagtttt aaaacgaaaa atcagtgtta 1050

 agtttgatgc agttattgga tataaaatga aagcgcaata agcacctagt 1100

 tttctgaaaa ctgatttacc aggtttaggt tgatgtcatc taatagtgcc 1150

 agaattttaa tgtttgaact tctgtttttt ctaattatcc ccatttcttc 1200

 aatatcattt ttgaggcttt ggcagtcttc atttactacc acttgttctt 1250

 tagccaaaag ctgattacat atgatataaa cagagaaata cctttagagg 1300

 tgactttaag gaaaatgaag aaaaagaacc aaaatgactt tattaaaata 1350

 atttccaaga ttatttgtgg ctcacctgaa ggctttgcaa aatttgtacc 1400

 ataaccgttt atttaacata tatttttatt tttgattgca cttaaatttt 1450

 gtataatttg tgtttctttt tctgttctac ataaaatcag aaacttcaag 1500

 ctctctaaat aaaatgaagg actatatcta gtggtatttc acaatgaata 1550

 tcatgaactc tcaatgggta ggtttcatcc tacccattgc cactctgttt 1600

 cctgagagat acctcacatt ccaatgccaa acatttctgc acagggaagc 1650

 tagaggtgga tacacgtgtt gcaagtataa aagcatcact gggggattta 1700

 aggagaattg agagaatgta cccacaaatg gcagcaataa taaatggatc 1750

 acacttaacg 1760

<210> 5828
<211> 300
<212> PRT
<213> Homo sapien

<400> 5828
 Met Lys Phe Leu Leu Asp Ile Leu Leu Leu Leu Pro Leu Leu Ile
   1               5                  10                  15

 Val Cys Ser Leu Glu Ser Phe Val Lys Leu Phe Ile Pro Lys Arg
                  20                  25                  30

 Arg Lys Ser Val Thr Gly Glu Ile Val Leu Ile Thr Gly Ala Gly
                  35                  40                  45

 His Gly Ile Gly Arg Leu Thr Ala Tyr Glu Phe Ala Lys Leu Lys
                  50                  55                  60

 Ser Lys Leu Val Leu Trp Asp Ile Asn Lys His Gly Leu Glu Glu
                  65                  70                  75

 Thr Ala Ala Lys Cys Lys Gly Leu Gly Ala Lys Val His Thr Phe
                  80                  85                  90

 Val Val Asp Cys Ser Asn Arg Glu Asp Ile Tyr Ser Ser Ala Lys
                  95                 100                 105

 Lys Val Lys Ala Glu Ile Gly Asp Val Ser Ile Leu Val Asn Asn
                 110                 115                 120

 Ala Gly Val Val Tyr Thr Ser Asp Leu Phe Ala Thr Gln Asp Pro
                 125                 130                 135

 Gln Ile Glu Lys Thr Phe Glu Val Asn Val Leu Ala His Phe Trp
                 140                 145                 150

 Thr Thr Lys Ala Phe Leu Pro Ala Met Thr Lys Asn Asn His Gly
                 155                 160                 165

 His Ile Val Thr Val Ala Ser Ala Ala Gly His Val Ser Val Pro
                 170                 175                 180

 Phe Leu Leu Ala Tyr Cys Ser Ser Lys Phe Ala Ala Val Gly Phe
                 185                 190                 195

 His Lys Thr Leu Thr Asp Glu Leu Ala Ala Leu Gln Ile Thr Gly
                 200                 205                 210

 Val Lys Thr Thr Cys Leu Cys Pro Asn Phe Val Asn Thr Gly Phe
                 215                 220                 225

 Ile Lys Asn Pro Ser Thr Ser Leu Gly Pro Thr Leu Glu Pro Glu
                 230                 235                 240

 Glu Val Val Asn Arg Leu Met His Gly Ile Leu Thr Glu Gln Lys
                 245                 250                 255

 Met Ile Phe Ile Pro Ser Ser Ile Ala Phe Leu Thr Thr Leu Glu
                 260                 265                 270

 Arg Ile Leu Pro Glu Arg Phe Leu Ala Val Leu Lys Arg Lys Ile
                 275                 280                 285

 Ser Val Lys Phe Asp Ala Val Ile Gly Tyr Lys Met Lys Ala Gln
                 290                 295                 300

<210> 5829
<211> 1206
<212> DNA
<213> Homo sapien

<400> 5829
 cccaggaaag cttgaaggca gagatagact cgcgtctcta agacatatac 50

 ataatatagc cgcaaccgcg gggcttactt tcccggagct gcatcccctt 100

 ttgggcgaag agcggaggca gaccagggac taccctaggt gaaagggcag 150

 ccacctggcc ctacccgggc tcaacgccga gcctctcgga ggtacggcct 200

 cccgggggac cttccagact ggtcggcgca agaaagggcg gggaccaccg 250

 aaggagtgtg tgacttaggc atccagcgca ctgcctgacc cgaagtaccg 300

 acccgagtta tgcccaccct ccaacttttg cggcggggac catgttgctt 350

 ccgaacatcc tgctcaccgg tacaccaggg gttggaaaaa ccacactagg 400

 caaagaactt gcgtcaaaat caggactgaa atacattaat gtgggtgatt 450

 tagctcgaga agagcaattg tatgatggct atgatgaaga gtatgactgt 500

 cccattttag atgaagacag agtagttgat gagttagata accaaatgag 550

 agaaggtgga gttattgttg attaccatgg ttgtgatttc ttccctgaac 600

 gctggtttca tatagttttt gtgctgagaa cagataccaa tgtattgtac 650

 gaaagacttg aaacaagggg ttataatgag aagaaactaa cagacaatat 700

 tcagtgtgag atttttcaag ttctttatga agaagccaca gcatcctaca 750

 aggaagaaat cgtgcatcag ctgcccagta ataaaccaga agagctagaa 800

 aataatgtag atcagatctt gaaatggatt gagcagtgga tcaaagatca 850

 taactcttga cttataaggc tagctactta ataatcactc ttgttgatat 900

 ctctgccgac atcatagaaa ttggtcaagt gtcagtaaca ctttattaaa 950

 atcatgttgc agaaccagca ggtggatagt atataggttt atgcctgggg 1000

 ttctttttct tcatgagaaa gctaaacatg aaatataatg aatatagtat 1050

 tattaaggat tgagacaaaa actgtgattt taatacttaa attgctaaag 1100

 aataaataaa tctgacaaaa tgggtggata tcttttaagt ttattacaga 1150

 aaaaaatgca gatgatctct taaaataaaa ctaaagataa agcaaaaaaa 1200

 aaaaaa 1206

<210> 5830
<211> 172
<212> PRT
<213> Homo sapien

<400> 5830
 Met Leu Leu Pro Asn Ile Leu Leu Thr Gly Thr Pro Gly Val Gly
   1               5                  10                  15

 Lys Thr Thr Leu Gly Lys Glu Leu Ala Ser Lys Ser Gly Leu Lys
                  20                  25                  30

 Tyr Ile Asn Val Gly Asp Leu Ala Arg Glu Glu Gln Leu Tyr Asp
                  35                  40                  45

 Gly Tyr Asp Glu Glu Tyr Asp Cys Pro Ile Leu Asp Glu Asp Arg
                  50                  55                  60

 Val Val Asp Glu Leu Asp Asn Gln Met Arg Glu Gly Gly Val Ile
                  65                  70                  75

 Val Asp Tyr His Gly Cys Asp Phe Phe Pro Glu Arg Trp Phe His
                  80                  85                  90

 Ile Val Phe Val Leu Arg Thr Asp Thr Asn Val Leu Tyr Glu Arg
                  95                 100                 105

 Leu Glu Thr Arg Gly Tyr Asn Glu Lys Lys Leu Thr Asp Asn Ile
                 110                 115                 120

 Gln Cys Glu Ile Phe Gln Val Leu Tyr Glu Glu Ala Thr Ala Ser
                 125                 130                 135

 Tyr Lys Glu Glu Ile Val His Gln Leu Pro Ser Asn Lys Pro Glu
                 140                 145                 150

 Glu Leu Glu Asn Asn Val Asp Gln Ile Leu Lys Trp Ile Glu Gln
                 155                 160                 165

 Trp Ile Lys Asp His Asn Ser
                 170

<210> 5831
<211> 2750
<212> DNA
<213> Homo sapien

<400> 5831
 ggctgccggg gaggccagag cgtggagcgc tgcgcggcgc ggcggccggg 50

 ccctcgagac ggggacggac acaccagccc ctcagatacc acttggccac 100

 tcccgctgag gccactccca ctgcgtggct gaagcctcga ggtcaccagg 150

 cggaggcgcg gagatgcccc tgcatcagct gggggacaag ccgctcacct 200

 tccccagccc caactcagcc atggaaaacg ggcttgacca caccccaccc 250

 agcaggaggg catccccggg cacacccctg agccccggct ccctccgctc 300

 cgctgcccat agccccctgg acaccagcaa gcagcccctc tgccagctct 350

 gggccgagaa gcatggcgcc cgggggaccc atgaggtgcg gtacatctcg 400

 gccgggcaga gcgtggcgtg cggctggtgg gccttcgcac cgccgtgcct 450

 gcaggtcctc aacacgccca agggcatcct gttcttcctg tgtgcggccg 500

 cattcctgca ggggatgact gtgaatggct tcatcaacac agtcatcacc 550

 tccctggagc gccgctatga cctgcacagc taccagagcg ggctcatcgc 600

 cagctcctac gacattgccg cctgcctctg cctcaccttc gtcagctact 650

 tcgggggctc agggcacaag ccgcgctggc tgggctgggg cgtgctgctt 700

 atgggcacgg gttcgctggt gttcgcgctg ccccacttca cggctggccg 750

 ctatgaggtg gagttggacg cgggtgtcag gacgtgccct gccaaccccg 800

 gcgcggtgtg tgcggacagc acctcgggcc tgtcccgcta ccagctggtc 850

 ttcatgctgg gccagttcct gcatggcgtg ggtgccacac ccctctacac 900

 gctgggcgtc acctacctgg atgagaacgt caagtccagc tgctcgcccg 950

 tctacattgc catcttctac acagcggcca tcctgggccc agctgccggc 1000

 tacctgattg gaggtgccct gctgaatatc tacacggaaa tgggccgacg 1050

 gacggagctg accaccgaga gcccactgtg ggtcggcgcc tggtgggtcg 1100

 gcttcctggg ctctggggcc gctgctttct tcaccgccgt tcccatcctt 1150

 ggttaccctc ggcagctgcc aggctcccag cgctacgcgg tcatgagagc 1200

 ggcggaaatg caccagttga aggacagcag ccgtggggag gcgagcaacc 1250

 cggactttgg gaaaaccatc agagacctgc ctctctccat ctggctcctg 1300

 ctgaagaacc ccacgttcat cctgctctgc ctggccgggg ccaccgaggc 1350

 cactctcatc accggcatgt ccacgttcag ccccaagttc ttggagtccc 1400

 agttcagcct gagtgcctca gaagctgcca ccttgtttgg gtacctggtg 1450

 gtgccagcgg gtggtggcgg caccttcctg ggcggcttct ttgtgaacaa 1500

 gctcaggctc cggggctccg cggtcatcaa gttctgcctg ttctgcaccg 1550

 ttgtcagcct gctgggcatc ctcgtcttct cactgcactg ccccagtgtg 1600

 cccatggcgg gcgtcacagc cagctacggc gggagcctcc tgcccgaagg 1650

 ccacctgaac ctaacggctc cctgcaacgc tgcctgcagc tgccagccag 1700

 aacactacag ccctgtgtgc ggctcggacg gcctcatgta cttctcactg 1750

 tgccacgcag ggtgccctgc agccacggag acgaatgtgg acggccagaa 1800

 ggtgtaccga gactgtagct gtatccctca gaatctttcc tctggttttg 1850

 gccatgccac tgcagggaaa tgcacttcaa cttgtcagag aaagcccctc 1900

 cttctggttt tcatattcgt tgtaattttc tttacattcc tcagcagcat 1950

 tcctgcacta acggcaactc tacgatgtgt ccgtgaccct cagagatcct 2000

 ttgccctggg aatccagtgg attgtagtta gaatactagg gggcatcccg 2050

 gggcccatcg ccttcggctg ggtgatcgac aaggcctgtc tgctgtggca 2100

 ggaccagtgt ggccagcagg gctcctgctt ggtgtaccag aattcggcca 2150

 tgagccgcta catactcatc atggggctcc tgtacaaggt gctgggcgtc 2200

 ctcttctttg ccatagcctg cttcttatac aagcccctgt cggagtcttc 2250

 agatggcctg gaaacttgtc tgcccagcca gtcctcagcc cctgacagtg 2300

 ccacagatag ccagctccag agcagcgtct gaccaccgcc cgcgcccacc 2350

 cggccacggc gggcactcag catttcctga tgacagaaca gtgccgttgg 2400

 gtgatgcaat cacacgggaa cttctatttg acctgcaacc ttctacttaa 2450

 cctgtggttt aaagtcggct gtgacctcct gtccccagag ctgtacggcc 2500

 ctgcagtggg tgggaggaac ttgcataaat atatatttat ggacacacag 2550

 tttgcatcag aacgtgttta tagaatgtgt tttatacccg atcgtgtgtg 2600

 gtgtgcgtga ggacaaactc cgcaggggct gtgaatccca ctgggagggc 2650

 ggcgggcctg cagcccgagg aaggcttgtg tgtcctcagt taaaactgtg 2700

 catatcgaaa tatattttgt tatttaagcc tgaaaaaaaa aaaaaaaaaa 2750

<210> 5832
<211> 722
<212> PRT
<213> Homo sapien

<400> 5832
 Met Pro Leu His Gln Leu Gly Asp Lys Pro Leu Thr Phe Pro Ser
   1               5                  10                  15

 Pro Asn Ser Ala Met Glu Asn Gly Leu Asp His Thr Pro Pro Ser
                  20                  25                  30

 Arg Arg Ala Ser Pro Gly Thr Pro Leu Ser Pro Gly Ser Leu Arg
                  35                  40                  45

 Ser Ala Ala His Ser Pro Leu Asp Thr Ser Lys Gln Pro Leu Cys
                  50                  55                  60

 Gln Leu Trp Ala Glu Lys His Gly Ala Arg Gly Thr His Glu Val
                  65                  70                  75

 Arg Tyr Ile Ser Ala Gly Gln Ser Val Ala Cys Gly Trp Trp Ala
                  80                  85                  90

 Phe Ala Pro Pro Cys Leu Gln Val Leu Asn Thr Pro Lys Gly Ile
                  95                 100                 105

 Leu Phe Phe Leu Cys Ala Ala Ala Phe Leu Gln Gly Met Thr Val
                 110                 115                 120

 Asn Gly Phe Ile Asn Thr Val Ile Thr Ser Leu Glu Arg Arg Tyr
                 125                 130                 135

 Asp Leu His Ser Tyr Gln Ser Gly Leu Ile Ala Ser Ser Tyr Asp
                 140                 145                 150

 Ile Ala Ala Cys Leu Cys Leu Thr Phe Val Ser Tyr Phe Gly Gly
                 155                 160                 165

 Ser Gly His Lys Pro Arg Trp Leu Gly Trp Gly Val Leu Leu Met
                 170                 175                 180

 Gly Thr Gly Ser Leu Val Phe Ala Leu Pro His Phe Thr Ala Gly
                 185                 190                 195

 Arg Tyr Glu Val Glu Leu Asp Ala Gly Val Arg Thr Cys Pro Ala
                 200                 205                 210

 Asn Pro Gly Ala Val Cys Ala Asp Ser Thr Ser Gly Leu Ser Arg
                 215                 220                 225

 Tyr Gln Leu Val Phe Met Leu Gly Gln Phe Leu His Gly Val Gly
                 230                 235                 240

 Ala Thr Pro Leu Tyr Thr Leu Gly Val Thr Tyr Leu Asp Glu Asn
                 245                 250                 255

 Val Lys Ser Ser Cys Ser Pro Val Tyr Ile Ala Ile Phe Tyr Thr
                 260                 265                 270

 Ala Ala Ile Leu Gly Pro Ala Ala Gly Tyr Leu Ile Gly Gly Ala
                 275                 280                 285

 Leu Leu Asn Ile Tyr Thr Glu Met Gly Arg Arg Thr Glu Leu Thr
                 290                 295                 300

 Thr Glu Ser Pro Leu Trp Val Gly Ala Trp Trp Val Gly Phe Leu
                 305                 310                 315

 Gly Ser Gly Ala Ala Ala Phe Phe Thr Ala Val Pro Ile Leu Gly
                 320                 325                 330

 Tyr Pro Arg Gln Leu Pro Gly Ser Gln Arg Tyr Ala Val Met Arg
                 335                 340                 345

 Ala Ala Glu Met His Gln Leu Lys Asp Ser Ser Arg Gly Glu Ala
                 350                 355                 360

 Ser Asn Pro Asp Phe Gly Lys Thr Ile Arg Asp Leu Pro Leu Ser
                 365                 370                 375

 Ile Trp Leu Leu Leu Lys Asn Pro Thr Phe Ile Leu Leu Cys Leu
                 380                 385                 390

 Ala Gly Ala Thr Glu Ala Thr Leu Ile Thr Gly Met Ser Thr Phe
                 395                 400                 405

 Ser Pro Lys Phe Leu Glu Ser Gln Phe Ser Leu Ser Ala Ser Glu
                 410                 415                 420

 Ala Ala Thr Leu Phe Gly Tyr Leu Val Val Pro Ala Gly Gly Gly
                 425                 430                 435

 Gly Thr Phe Leu Gly Gly Phe Phe Val Asn Lys Leu Arg Leu Arg
                 440                 445                 450

 Gly Ser Ala Val Ile Lys Phe Cys Leu Phe Cys Thr Val Val Ser
                 455                 460                 465

 Leu Leu Gly Ile Leu Val Phe Ser Leu His Cys Pro Ser Val Pro
                 470                 475                 480

 Met Ala Gly Val Thr Ala Ser Tyr Gly Gly Ser Leu Leu Pro Glu
                 485                 490                 495

 Gly His Leu Asn Leu Thr Ala Pro Cys Asn Ala Ala Cys Ser Cys
                 500                 505                 510

 Gln Pro Glu His Tyr Ser Pro Val Cys Gly Ser Asp Gly Leu Met
                 515                 520                 525

 Tyr Phe Ser Leu Cys His Ala Gly Cys Pro Ala Ala Thr Glu Thr
                 530                 535                 540

 Asn Val Asp Gly Gln Lys Val Tyr Arg Asp Cys Ser Cys Ile Pro
                 545                 550                 555

 Gln Asn Leu Ser Ser Gly Phe Gly His Ala Thr Ala Gly Lys Cys
                 560                 565                 570

 Thr Ser Thr Cys Gln Arg Lys Pro Leu Leu Leu Val Phe Ile Phe
                 575                 580                 585

 Val Val Ile Phe Phe Thr Phe Leu Ser Ser Ile Pro Ala Leu Thr
                 590                 595                 600

 Ala Thr Leu Arg Cys Val Arg Asp Pro Gln Arg Ser Phe Ala Leu
                 605                 610                 615

 Gly Ile Gln Trp Ile Val Val Arg Ile Leu Gly Gly Ile Pro Gly
                 620                 625                 630

 Pro Ile Ala Phe Gly Trp Val Ile Asp Lys Ala Cys Leu Leu Trp
                 635                 640                 645

 Gln Asp Gln Cys Gly Gln Gln Gly Ser Cys Leu Val Tyr Gln Asn
                 650                 655                 660

 Ser Ala Met Ser Arg Tyr Ile Leu Ile Met Gly Leu Leu Tyr Lys
                 665                 670                 675

 Val Leu Gly Val Leu Phe Phe Ala Ile Ala Cys Phe Leu Tyr Lys
                 680                 685                 690

 Pro Leu Ser Glu Ser Ser Asp Gly Leu Glu Thr Cys Leu Pro Ser
                 695                 700                 705

 Gln Ser Ser Ala Pro Asp Ser Ala Thr Asp Ser Gln Leu Gln Ser
                 710                 715                 720

 Ser Val


<210> 5833
<211> 5601
<212> DNA
<213> Homo sapien

<400> 5833
 ggcccggctg cgaggaggag gcggcggcgg cgcaggagga tgtacttggt 50

 ggcgggggac agggggttgg ccggctgcgg gcacctcctg gtctcgctgc 100

 tggggctgct gctgctgctg gcgcgctccg gcacccgggc gctggtctgc 150

 ctgccctgtg acgagtccaa gtgcgaggag cccaggaact gcccggggag 200

 catcgtgcag ggcgtctgcg gctgctgcta cacgtgcgcc agccagagga 250

 acgagagctg cggcggcacc ttcgggattt acggaacctg cgaccggggg 300

 ctgcgttgtg tcatccgccc cccgctcaat ggcgactccc tcaccgagta 350

 cgaagcgggc gtttgcgaag atgagaactg gactgatgac caactgcttg 400

 gttttaaacc atgcaatgaa aaccttattg ctggctgcaa tataatcaat 450

 gggaaatgtg aatgtaacac cattcgaacc tgcagcaatc cctttgagtt 500

 tccaagtcag gatatgtgcc tttcagcttt aaagagaatt gaagaagaga 550

 agccagattg ctccaaggcc cgctgtgaag tccagttctc tccacgttgt 600

 cctgaagatt ctgttctgat cgagggttat gctcctcctg gggagtgctg 650

 tcccttaccc agccgctgcg tgtgcaaccc cgcaggctgt ctgcgcaaag 700

 tctgccagcc gggaaacctg aacatactag tgtcaaaagc ctcagggaag 750

 ccgggagagt gctgtgacct ctatgagtgc aaaccagttt tcggcgtgga 800

 ctgcaggact gtggaatgcc ctcctgttca gcagaccgcg tgtcccccgg 850

 acagctatga aactcaagtc agactaactg cagatggttg ctgtactttg 900

 ccaacaagat gcgagtgtct ctctggctta tgtggtttcc ccgtgtgtga 950

 ggtgggatcc actccccgca tagtctctcg tggcgatggg acacctggaa 1000

 agtgctgtga tgtctttgaa tgtgttaatg atacaaagcc agcctgcgta 1050

 tttaacaatg tggaatatta tgatggagac atgtttcgaa tggacaactg 1100

 tcggttctgt cgatgccaag ggggcgttgc catctgcttc actgcccagt 1150

 gtggtgagat aaactgcgag aggtactacg tgcccgaagg agagtgctgc 1200

 ccagtgtgtg aagatccagt gtatcctttt aataatcccg ctggctgcta 1250

 tgccaatggc ctgatccttg cccacggaga ccggtggcgg gaagacgact 1300

 gcacattctg ccagtgcgtc aacggtgaac gccactgcgt tgcgaccgtc 1350

 tgcggacaga cctgcacaaa ccctgtgaaa gtgcctgggg agtgttgccc 1400

 tgtgtgcgaa gaaccaacca tcatcacagt tgatccacct gcatgtgggg 1450

 agttatcaaa ctgcactctg acagggaagg actgcattaa tggtttcaaa 1500

 cgcgatcaca atggttgtcg gacctgtcag tgcataaaca ccgaggaact 1550

 atgttcagaa cgtaaacaag gctgcacctt gaactgtccc ttcggtttcc 1600

 ttactgatgc ccaaaactgt gagatctgtg agtgccgccc aaggcccaag 1650

 aagtgcagac ccataatctg tgacaagtat tgtccacttg gattgctgaa 1700

 gaataagcac ggctgtgaca tctgtcgctg taagaaatgt ccagagctct 1750

 catgcagtaa gatctgcccc ttgggtttcc agcaggacag tcacggctgt 1800

 cttatctgca agtgcagaga ggcctctgct tcagctgggc cacccatcct 1850

 gtcgggcact tgtctcaccg tggatggtca tcatcataaa aatgaggaga 1900

 gctggcacga tgggtgccgg gaatgctact gtctcaatgg acgggaaatg 1950

 tgtgccctga tcacctgccc ggtgcctgcc tgtggcaacc ccaccattca 2000

 ccctggacag tgctgcccat catgtgcaga tgactttgtg gtgcagaagc 2050

 cagagctcag tactccctcc atttgccacg cccctggagg agaatacttt 2100

 gtggaaggag aaacgtggaa cattgactcc tgtactcagt gcacctgcca 2150

 cagcggacgg gtgctgtgtg agacagaggt gtgcccaccg ctgctctgcc 2200

 agaacccctc acgcacccag gattcctgct gcccacagtg tacagatcaa 2250

 ccttttcggc cttccttgtc ccgcaataac agcgtaccta attactgcaa 2300

 aaatgatgaa ggggatatat tcctggcagc tgagtcctgg aagcctgacg 2350

 tttgtaccag ctgcatctgc attgatagcg taattagctg tttctctgag 2400

 tcctgccctt ctgtatcctg tgaaagacct gtcttgagaa aaggccagtg 2450

 ttgtccctac tgcatagaag acacaattcc aaagaaggtg gtgtgccact 2500

 tcagtgggaa ggcctatgcc gacgaggagc ggtgggacct tgacagctgc 2550

 acccactgct actgcctgca gggccagacc ctctgctcga ccgtcagctg 2600

 cccccctctg ccctgtgttg agcccatcaa cgtggaagga agttgctgcc 2650

 caatgtgtcc agaaatgtat gtcccagaac caaccaatat acccattgag 2700

 aagacaaacc atcgaggaga ggttgacctg gaggttcccc tgtggcccac 2750

 gcctagtgaa aatgatatcg tccatctccc tagagatatg ggtcacctcc 2800

 aggtagatta cagagataac aggctgcacc caagtgaaga ttcttcactg 2850

 gactccattg cctcagttgt ggttcccata attatatgcc tctctattat 2900

 aatagcattc ctattcatca atcagaagaa acagtggata ccactgcttt 2950

 gctggtatcg aacaccaact aagccttctt ccttaaataa tcagctagta 3000

 tctgtggact gcaagaaagg aaccagagtc caggtggaca gttcccagag 3050

 aatgctaaga attgcagaac cagatgcaag attcagtggc ttctacagca 3100

 tgcaaaaaca gaaccatcta caggcagaca atttctacca aacagtgtga 3150

 agaaaggcaa ctaggatgag gtttcaaaag acggaagacg actaaatctg 3200

 ctctaaaaag taaactagaa tttgtgcact tgcttagtgg attgtattgg 3250

 attgtgactt gatgtacagc gctaagacct tactgggatg ggctctgtct 3300

 acagcaatgt gcagaacaag cattcccact tttcctcaag ataactgacc 3350

 aagtgttttc ttagaaccaa agtttttaaa gttgctaaga tatatttgcc 3400

 tgtaagatag ctgtagagat atttggggtg gggacagtga gtttggatgg 3450

 ggaaatgggt gggagggtgg tgttgggaag aaaaattggt cagcttggct 3500

 cggggagaaa cctggtaaca taaaagcagt tcagtggccc agaggttatt 3550

 tttttcctat tgctctgaag actgcactgg ttgctgcaaa gctcaggcct 3600

 gaatgagcag gaaacaaaaa aggccttgcg acccagctgc cataaccacc 3650

 ttagaactac cagacgagca catcagaacc ctttgacagc catcccaggt 3700

 ctaaagccac aagtttcttt tctatacagt cacaactgca gtaggcagtg 3750

 aggaagccag agaaatgcga tagcggcatt tctctaaagc gggttattaa 3800

 ggatatatac agttacactt tttgctgctt ttattttctt ccaagccaat 3850

 caatcagcca gttcctagca gagtcagcac atgaacaaga tctaagtcat 3900

 ttcttgatgt gagcactgga gctttttttt ttttacaacg tgacaggaag 3950

 aggagggaga gggtgacgaa caccaggcat ttccaggggc tatatttcac 4000

 tgtttgttgt tgctttgttc tgttatattg ttggttgttc atagtttttg 4050

 ttgaagctct agcttaagaa gaaacttttt ttaaaaagac tgtttgggga 4100

 ttctttttcc ttattatata ctgattctac aaaatagaaa ctacttcatt 4150

 ttaattgtat attattcaag cacctttgtt gaagctcaaa aaaaatgatg 4200

 cctctttaaa ctttagcaat tataggagta tttatgtaac tatcttatgc 4250

 ttcaaaaaac aaaagtattt gtgtgcatgt gtatataata tatatatata 4300

 catatatatt tatacacata caatttatgt tttcctgttg aatgtatttt 4350

 tatgagattt taaccagaac aaaggcagat aaacaggcat tccatagcag 4400

 tgcttttgat cacttacaaa ttttttgaat aacacaaaat ctcattctac 4450

 ctgcagttta attggaaaga tgtgtgtgtg agagtatgta tgtgtgtgtg 4500

 tgtgtgtgtg tgtgtgcgcg cgcacgcacg ccttgagcag tcagcattgc 4550

 acctgctatg gagaagggta ttcctttatt aaaatcttcc tcatttggat 4600

 ttgctttcag ttggttttca atttgctcac tggccagaga cattgatggc 4650

 agttcttatc tgcatcacta atcagctcct ggattttttt tttttttttt 4700

 tcaaacaatg gtttgaaaca actactggaa tattgtccac aataagctgg 4750

 aagtttgttg tagtatgcct caaatataac tgactgtata ctatagtggt 4800

 aacttttcaa acagccctta gcacttttat actaattaac ccatttgtgc 4850

 attgagtttt cttttaaaaa tgcttgttgt gaaagacaca gatacccagt 4900

 atgcttaacg tgaaaagaaa atgtgttctg ttttgtaaag gaactttcaa 4950

 gtattgttgt aaatacttgg acagaggttg ctgaacttta aaaaaaatta 5000

 atttattatt ataatgacct aatttattaa tctgaagatt aaccattttt 5050

 ttgtcttaga atatcaaaaa gaaaaagaaa aaggtgttct agctgtttgc 5100

 atcaaaggaa aaaaagattt attatcaagg ggcaatattt ttatcttttc 5150

 caaaataaat ttgttaatga tacattacaa aaatagattg acatcagcct 5200

 gattagtata aattttgttg gtaattaatc cattcctggc ataaaaagtc 5250

 tttatcaaaa aaaattgtag atgcttgctt tttgtttttt caatcatggc 5300

 catattatga aaatactaac aggatatagg acaaggtgta aattttttta 5350

 ttattatttt aaagatatga tttatcctga gtgctgtatc tattactctt 5400

 ttactttggt tcctgttgtg ctcttgtaaa agaaaaatat aatttcctga 5450

 agaataaaat agatatatgg cacttggagt gcatcatagt tctacagttt 5500

 gtttttgttt tcttcaaaaa agctgtaaga gaattatctg caacttgatt 5550

 cttggcagga aataaacatt ttgagttgaa atcaaaaaaa aaaaaaaaaa 5600

 a 5601

<210> 5834
<211> 1036
<212> PRT
<213> Homo sapien

<400> 5834
 Met Tyr Leu Val Ala Gly Asp Arg Gly Leu Ala Gly Cys Gly His
   1               5                  10                  15

 Leu Leu Val Ser Leu Leu Gly Leu Leu Leu Leu Leu Ala Arg Ser
                  20                  25                  30

 Gly Thr Arg Ala Leu Val Cys Leu Pro Cys Asp Glu Ser Lys Cys
                  35                  40                  45

 Glu Glu Pro Arg Asn Cys Pro Gly Ser Ile Val Gln Gly Val Cys
                  50                  55                  60

 Gly Cys Cys Tyr Thr Cys Ala Ser Gln Arg Asn Glu Ser Cys Gly
                  65                  70                  75

 Gly Thr Phe Gly Ile Tyr Gly Thr Cys Asp Arg Gly Leu Arg Cys
                  80                  85                  90

 Val Ile Arg Pro Pro Leu Asn Gly Asp Ser Leu Thr Glu Tyr Glu
                  95                 100                 105

 Ala Gly Val Cys Glu Asp Glu Asn Trp Thr Asp Asp Gln Leu Leu
                 110                 115                 120

 Gly Phe Lys Pro Cys Asn Glu Asn Leu Ile Ala Gly Cys Asn Ile
                 125                 130                 135

 Ile Asn Gly Lys Cys Glu Cys Asn Thr Ile Arg Thr Cys Ser Asn
                 140                 145                 150

 Pro Phe Glu Phe Pro Ser Gln Asp Met Cys Leu Ser Ala Leu Lys
                 155                 160                 165

 Arg Ile Glu Glu Glu Lys Pro Asp Cys Ser Lys Ala Arg Cys Glu
                 170                 175                 180

 Val Gln Phe Ser Pro Arg Cys Pro Glu Asp Ser Val Leu Ile Glu
                 185                 190                 195

 Gly Tyr Ala Pro Pro Gly Glu Cys Cys Pro Leu Pro Ser Arg Cys
                 200                 205                 210

 Val Cys Asn Pro Ala Gly Cys Leu Arg Lys Val Cys Gln Pro Gly
                 215                 220                 225

 Asn Leu Asn Ile Leu Val Ser Lys Ala Ser Gly Lys Pro Gly Glu
                 230                 235                 240

 Cys Cys Asp Leu Tyr Glu Cys Lys Pro Val Phe Gly Val Asp Cys
                 245                 250                 255

 Arg Thr Val Glu Cys Pro Pro Val Gln Gln Thr Ala Cys Pro Pro
                 260                 265                 270

 Asp Ser Tyr Glu Thr Gln Val Arg Leu Thr Ala Asp Gly Cys Cys
                 275                 280                 285

 Thr Leu Pro Thr Arg Cys Glu Cys Leu Ser Gly Leu Cys Gly Phe
                 290                 295                 300

 Pro Val Cys Glu Val Gly Ser Thr Pro Arg Ile Val Ser Arg Gly
                 305                 310                 315

 Asp Gly Thr Pro Gly Lys Cys Cys Asp Val Phe Glu Cys Val Asn
                 320                 325                 330

 Asp Thr Lys Pro Ala Cys Val Phe Asn Asn Val Glu Tyr Tyr Asp
                 335                 340                 345

 Gly Asp Met Phe Arg Met Asp Asn Cys Arg Phe Cys Arg Cys Gln
                 350                 355                 360

 Gly Gly Val Ala Ile Cys Phe Thr Ala Gln Cys Gly Glu Ile Asn
                 365                 370                 375

 Cys Glu Arg Tyr Tyr Val Pro Glu Gly Glu Cys Cys Pro Val Cys
                 380                 385                 390

 Glu Asp Pro Val Tyr Pro Phe Asn Asn Pro Ala Gly Cys Tyr Ala
                 395                 400                 405

 Asn Gly Leu Ile Leu Ala His Gly Asp Arg Trp Arg Glu Asp Asp
                 410                 415                 420

 Cys Thr Phe Cys Gln Cys Val Asn Gly Glu Arg His Cys Val Ala
                 425                 430                 435

 Thr Val Cys Gly Gln Thr Cys Thr Asn Pro Val Lys Val Pro Gly
                 440                 445                 450

 Glu Cys Cys Pro Val Cys Glu Glu Pro Thr Ile Ile Thr Val Asp
                 455                 460                 465

 Pro Pro Ala Cys Gly Glu Leu Ser Asn Cys Thr Leu Thr Gly Lys
                 470                 475                 480

 Asp Cys Ile Asn Gly Phe Lys Arg Asp His Asn Gly Cys Arg Thr
                 485                 490                 495

 Cys Gln Cys Ile Asn Thr Glu Glu Leu Cys Ser Glu Arg Lys Gln
                 500                 505                 510

 Gly Cys Thr Leu Asn Cys Pro Phe Gly Phe Leu Thr Asp Ala Gln
                 515                 520                 525

 Asn Cys Glu Ile Cys Glu Cys Arg Pro Arg Pro Lys Lys Cys Arg
                 530                 535                 540

 Pro Ile Ile Cys Asp Lys Tyr Cys Pro Leu Gly Leu Leu Lys Asn
                 545                 550                 555

 Lys His Gly Cys Asp Ile Cys Arg Cys Lys Lys Cys Pro Glu Leu
                 560                 565                 570

 Ser Cys Ser Lys Ile Cys Pro Leu Gly Phe Gln Gln Asp Ser His
                 575                 580                 585

 Gly Cys Leu Ile Cys Lys Cys Arg Glu Ala Ser Ala Ser Ala Gly
                 590                 595                 600

 Pro Pro Ile Leu Ser Gly Thr Cys Leu Thr Val Asp Gly His His
                 605                 610                 615

 His Lys Asn Glu Glu Ser Trp His Asp Gly Cys Arg Glu Cys Tyr
                 620                 625                 630

 Cys Leu Asn Gly Arg Glu Met Cys Ala Leu Ile Thr Cys Pro Val
                 635                 640                 645

 Pro Ala Cys Gly Asn Pro Thr Ile His Pro Gly Gln Cys Cys Pro
                 650                 655                 660

 Ser Cys Ala Asp Asp Phe Val Val Gln Lys Pro Glu Leu Ser Thr
                 665                 670                 675

 Pro Ser Ile Cys His Ala Pro Gly Gly Glu Tyr Phe Val Glu Gly
                 680                 685                 690

 Glu Thr Trp Asn Ile Asp Ser Cys Thr Gln Cys Thr Cys His Ser
                 695                 700                 705

 Gly Arg Val Leu Cys Glu Thr Glu Val Cys Pro Pro Leu Leu Cys
                 710                 715                 720

 Gln Asn Pro Ser Arg Thr Gln Asp Ser Cys Cys Pro Gln Cys Thr
                 725                 730                 735

 Asp Gln Pro Phe Arg Pro Ser Leu Ser Arg Asn Asn Ser Val Pro
                 740                 745                 750

 Asn Tyr Cys Lys Asn Asp Glu Gly Asp Ile Phe Leu Ala Ala Glu
                 755                 760                 765

 Ser Trp Lys Pro Asp Val Cys Thr Ser Cys Ile Cys Ile Asp Ser
                 770                 775                 780

 Val Ile Ser Cys Phe Ser Glu Ser Cys Pro Ser Val Ser Cys Glu
                 785                 790                 795

 Arg Pro Val Leu Arg Lys Gly Gln Cys Cys Pro Tyr Cys Ile Glu
                 800                 805                 810

 Asp Thr Ile Pro Lys Lys Val Val Cys His Phe Ser Gly Lys Ala
                 815                 820                 825

 Tyr Ala Asp Glu Glu Arg Trp Asp Leu Asp Ser Cys Thr His Cys
                 830                 835                 840

 Tyr Cys Leu Gln Gly Gln Thr Leu Cys Ser Thr Val Ser Cys Pro
                 845                 850                 855

 Pro Leu Pro Cys Val Glu Pro Ile Asn Val Glu Gly Ser Cys Cys
                 860                 865                 870

 Pro Met Cys Pro Glu Met Tyr Val Pro Glu Pro Thr Asn Ile Pro
                 875                 880                 885

 Ile Glu Lys Thr Asn His Arg Gly Glu Val Asp Leu Glu Val Pro
                 890                 895                 900

 Leu Trp Pro Thr Pro Ser Glu Asn Asp Ile Val His Leu Pro Arg
                 905                 910                 915

 Asp Met Gly His Leu Gln Val Asp Tyr Arg Asp Asn Arg Leu His
                 920                 925                 930

 Pro Ser Glu Asp Ser Ser Leu Asp Ser Ile Ala Ser Val Val Val
                 935                 940                 945

 Pro Ile Ile Ile Cys Leu Ser Ile Ile Ile Ala Phe Leu Phe Ile
                 950                 955                 960

 Asn Gln Lys Lys Gln Trp Ile Pro Leu Leu Cys Trp Tyr Arg Thr
                 965                 970                 975

 Pro Thr Lys Pro Ser Ser Leu Asn Asn Gln Leu Val Ser Val Asp
                 980                 985                 990

 Cys Lys Lys Gly Thr Arg Val Gln Val Asp Ser Ser Gln Arg Met
                 995                1000                1005

 Leu Arg Ile Ala Glu Pro Asp Ala Arg Phe Ser Gly Phe Tyr Ser
                1010                1015                1020

 Met Gln Lys Gln Asn His Leu Gln Ala Asp Asn Phe Tyr Gln Thr
                1025                1030                1035

 Val


<210> 5835
<211> 1011
<212> DNA
<213> Homo sapien

<400> 5835
 ggcacaacag agccgctccc ctctcctcgc cccgccaccg ggacgagagg 50

 cgcccgccgc tgcatttccg gcgacacctc gcagtcattc ctgcggcttg 100

 cgcgcccttg tagacagccg gggccttcgt gagaccggtg caggcctggg 150

 gtagtctcct gtctggacag agaagagaaa aatgcaggac actggctcag 200

 tagtgccttt gcattggttt ggctttggct acgcagcact ggttgcttct 250

 ggtgggatca ttggctatgt aaaagcaggc agcgtgccgt ccctggctgc 300

 agggctgctc tttggcagtc tagccggcct gggtgcttac cagctgtctc 350

 aggatccaag gaacgtttgg gttttcctag ctacatctgg taccttggct 400

 ggcattatgg gaatgaggtt ctaccactct ggaaaattca tgcctgcagg 450

 tttaattgca ggtgccagtt tgctgatggt cgccaaagtt ggagttagta 500

 tgttcaacag accccattag cagaagtcat gttccagctt agactgatga 550

 agaattaaaa atctgcatct tccactattt tcaatatatt aagagaaata 600

 agtgcagcat ttttgcatct gacattttac ctaaaaaaaa agacaccaaa 650

 cttggcagag aggtggaaaa tcagtcatga ttacaaacct acagaggtgg 700

 cgagtatgta acacaagagc ttaataagac cctcatagag cttgattctt 750

 gtatattgat gttgtctttt ctttctgtat ctgtaggtaa atctcaaggg 800

 taaaatgtta ggtgtcagct ttcagggctc tgaaacccta ttccctgctc 850

 tgaggaacag tgtgaaaaaa agtcttttag gagatttaca atatctgttc 900

 ttttgctcat cttagaccac agactgactt tgaaattatg ttaagtgaaa 950

 tatcaatgaa aataaagttt actataaata ataaaaaaaa aaaaaaaaaa 1000

 aaaaaaaaaa a 1011

<210> 5836
<211> 112
<212> PRT
<213> Homo sapien

<400> 5836
 Met Gln Asp Thr Gly Ser Val Val Pro Leu His Trp Phe Gly Phe
   1               5                  10                  15

 Gly Tyr Ala Ala Leu Val Ala Ser Gly Gly Ile Ile Gly Tyr Val
                  20                  25                  30

 Lys Ala Gly Ser Val Pro Ser Leu Ala Ala Gly Leu Leu Phe Gly
                  35                  40                  45

 Ser Leu Ala Gly Leu Gly Ala Tyr Gln Leu Ser Gln Asp Pro Arg
                  50                  55                  60

 Asn Val Trp Val Phe Leu Ala Thr Ser Gly Thr Leu Ala Gly Ile
                  65                  70                  75

 Met Gly Met Arg Phe Tyr His Ser Gly Lys Phe Met Pro Ala Gly
                  80                  85                  90

 Leu Ile Ala Gly Ala Ser Leu Leu Met Val Ala Lys Val Gly Val
                  95                 100                 105

 Ser Met Phe Asn Arg Pro His
                 110

<210> 5837
<211> 2527
<212> DNA
<213> Homo sapien

<400> 5837
 ccagccctgg cgtgggccca gcccggccca ggcagcaatg gggttcctgc 50

 agctgctggt cgtagcggtg ctggcatccg aacaccgggt ggctggtgca 100

 gccgaggtct tcgggaattc cagcgagggt cttattgaat tttctgtggg 150

 gaaatttaga tacttcgagc tcaataggcc ctttccagag gaagctattt 200

 tgcatgatat ttcaagcaat gtgacttttc ttattttcca aatacactca 250

 cagtatcaga atacaactgt ttccttttct ccgactctcc tttccaattc 300

 ctcggaaaca ggcactgcca gtggactggt tttcatcctt agaccagagc 350

 agagtacatg cacttggtac ttggggactt caggcataca gcctgtccag 400

 aatatggcta tcctactctc ctactcagaa agagatcctg tccctggagg 450

 ctgtaatttg gagttcgatt tagatattga tcccaacatt tacttggagt 500

 ataatttctt tgaaacgact atcaagtttg ccccagcaaa cctaggctat 550

 gcgagaggcg tagatccccc accatgtgac gctgggacag accaggactc 600

 caggtggagg ttgcagtatg atgtctatca gtattttctg cctgagaatg 650

 acctcactga ggagatgttg ctgaagcatc tgcagaggat ggtcagtgtg 700

 ccccaggtga aggccagtgc tctcaaggtg gttaccctaa cagctaatga 750

 taagacaagt gtttccttct cctccctccc gggacaaggt gtcatataca 800

 atgtcattgt ttgggacccg tttctaaata catctgctgc ctacattcct 850

 gctcacacat acgcttgcag ctttgaggca ggagagggta gttgtgcttc 900

 cctaggaaga gtgtcttcca aagtgttctt cactcttttt gccctgcttg 950

 gtttcttcat ttgtttcttt ggacacagat tctggaaaac agaattattc 1000

 ttcataggct ttatcatcat gggattcttc ttttatatac tgattacaag 1050

 actgacacct atcaagtatg atgtgaatct gattctgaca gctgtcactg 1100

 gaagcgtcgg tggaatgttc ttggtagctg tgtggtggcg atttggaatc 1150

 ctctcgatct gcatgctctg tgttggacta gtgctggggt tcctcatctc 1200

 gtcagtgact ttctttactc cactgggaaa cctaaagatt tttcatgatg 1250

 atggtgtatt ctgggtcact ttctcttgca tagctatcct cattccagta 1300

 gttttcatgg gctgcctaag aatactgaac atactgactt gtggagtcat 1350

 tggctcctat tcggtggttt tagccattga cagttactgg tccacaagcc 1400

 tttcctacat cactttgaac gtactcaaga gagcgctcaa caaggatttc 1450

 cacagagctt tcacaaatgt gccttttcaa actaatgact tcattatcct 1500

 ggcagtatgg ggcatgctgg ctgtaagtgg aattacgtta cagattcgaa 1550

 gagagagagg acgaccgttc ttccctcccc acccatacaa gttatggaag 1600

 caagagagag agcgccgagt gacaaacatt ctggacccta gctaccacat 1650

 tcctccattg agagagaggc tctatggccg attaacccag attaaagggc 1700

 tcttccagaa ggagcagcca gctggagaga gaacgccttt gcttctgtag 1750

 atgcccaggg gcttggtcag tgtgcctcag ctttggagtt catgcctgga 1800

 gtggttcaac agtctctggt gcaagtctaa taagagatca ggcatatata 1850

 tctgttcttt gcataatatt atggtgccct tattgatata tggtaagggt 1900

 gtactagggg attaggatga ttgtaagaga atgagaaaga tgaccaaaag 1950

 gttggtggta gggaggcttt ttcttatttc caaatacttg agaaattacc 2000

 ttttggttta caaatctatg atcaacttat tccattaaat agatacatta 2050

 aaaaaattaa aaactgcaaa aaaaaaaaaa aaactggtgt ttctttttat 2100

 aaccccttga aacaagtctc tcacctgagc ctgtctaaac tttcggaggg 2150

 agtttattat tgagtcttta tctgtgacag tatttggaga tttagggatt 2200

 tgatacttag gcctttgaat tttagaatac aaaaagagaa gcaagccaga 2250

 catggtggct cacacctgta atcccaatac tgggaagcca aggtgggagt 2300

 atcgcttgag cccaggagtt tgagaccgac atgggcaaca tgacaagacc 2350

 ccatctctac aaaaaaaatt aaaaaattag ccaggcatgg tggcacatgc 2400

 ctactcccag ctcccaagga gactgagatg ggaggatccc tggagccctg 2450

 aagattgagg ctacagtgag ccttgattgt gtcactgcac tccagcttgg 2500

 gtgacagaga ccctgtctcg agaaatt 2527

<210> 5838
<211> 570
<212> PRT
<213> Homo sapien

<400> 5838
 Met Gly Phe Leu Gln Leu Leu Val Val Ala Val Leu Ala Ser Glu
   1               5                  10                  15

 His Arg Val Ala Gly Ala Ala Glu Val Phe Gly Asn Ser Ser Glu
                  20                  25                  30

 Gly Leu Ile Glu Phe Ser Val Gly Lys Phe Arg Tyr Phe Glu Leu
                  35                  40                  45

 Asn Arg Pro Phe Pro Glu Glu Ala Ile Leu His Asp Ile Ser Ser
                  50                  55                  60

 Asn Val Thr Phe Leu Ile Phe Gln Ile His Ser Gln Tyr Gln Asn
                  65                  70                  75

 Thr Thr Val Ser Phe Ser Pro Thr Leu Leu Ser Asn Ser Ser Glu
                  80                  85                  90

 Thr Gly Thr Ala Ser Gly Leu Val Phe Ile Leu Arg Pro Glu Gln
                  95                 100                 105

 Ser Thr Cys Thr Trp Tyr Leu Gly Thr Ser Gly Ile Gln Pro Val
                 110                 115                 120

 Gln Asn Met Ala Ile Leu Leu Ser Tyr Ser Glu Arg Asp Pro Val
                 125                 130                 135

 Pro Gly Gly Cys Asn Leu Glu Phe Asp Leu Asp Ile Asp Pro Asn
                 140                 145                 150

 Ile Tyr Leu Glu Tyr Asn Phe Phe Glu Thr Thr Ile Lys Phe Ala
                 155                 160                 165

 Pro Ala Asn Leu Gly Tyr Ala Arg Gly Val Asp Pro Pro Pro Cys
                 170                 175                 180

 Asp Ala Gly Thr Asp Gln Asp Ser Arg Trp Arg Leu Gln Tyr Asp
                 185                 190                 195

 Val Tyr Gln Tyr Phe Leu Pro Glu Asn Asp Leu Thr Glu Glu Met
                 200                 205                 210

 Leu Leu Lys His Leu Gln Arg Met Val Ser Val Pro Gln Val Lys
                 215                 220                 225

 Ala Ser Ala Leu Lys Val Val Thr Leu Thr Ala Asn Asp Lys Thr
                 230                 235                 240

 Ser Val Ser Phe Ser Ser Leu Pro Gly Gln Gly Val Ile Tyr Asn
                 245                 250                 255

 Val Ile Val Trp Asp Pro Phe Leu Asn Thr Ser Ala Ala Tyr Ile
                 260                 265                 270

 Pro Ala His Thr Tyr Ala Cys Ser Phe Glu Ala Gly Glu Gly Ser
                 275                 280                 285

 Cys Ala Ser Leu Gly Arg Val Ser Ser Lys Val Phe Phe Thr Leu
                 290                 295                 300

 Phe Ala Leu Leu Gly Phe Phe Ile Cys Phe Phe Gly His Arg Phe
                 305                 310                 315

 Trp Lys Thr Glu Leu Phe Phe Ile Gly Phe Ile Ile Met Gly Phe
                 320                 325                 330

 Phe Phe Tyr Ile Leu Ile Thr Arg Leu Thr Pro Ile Lys Tyr Asp
                 335                 340                 345

 Val Asn Leu Ile Leu Thr Ala Val Thr Gly Ser Val Gly Gly Met
                 350                 355                 360

 Phe Leu Val Ala Val Trp Trp Arg Phe Gly Ile Leu Ser Ile Cys
                 365                 370                 375

 Met Leu Cys Val Gly Leu Val Leu Gly Phe Leu Ile Ser Ser Val
                 380                 385                 390

 Thr Phe Phe Thr Pro Leu Gly Asn Leu Lys Ile Phe His Asp Asp
                 395                 400                 405

 Gly Val Phe Trp Val Thr Phe Ser Cys Ile Ala Ile Leu Ile Pro
                 410                 415                 420

 Val Val Phe Met Gly Cys Leu Arg Ile Leu Asn Ile Leu Thr Cys
                 425                 430                 435

 Gly Val Ile Gly Ser Tyr Ser Val Val Leu Ala Ile Asp Ser Tyr
                 440                 445                 450

 Trp Ser Thr Ser Leu Ser Tyr Ile Thr Leu Asn Val Leu Lys Arg
                 455                 460                 465

 Ala Leu Asn Lys Asp Phe His Arg Ala Phe Thr Asn Val Pro Phe
                 470                 475                 480

 Gln Thr Asn Asp Phe Ile Ile Leu Ala Val Trp Gly Met Leu Ala
                 485                 490                 495

 Val Ser Gly Ile Thr Leu Gln Ile Arg Arg Glu Arg Gly Arg Pro
                 500                 505                 510

 Phe Phe Pro Pro His Pro Tyr Lys Leu Trp Lys Gln Glu Arg Glu
                 515                 520                 525

 Arg Arg Val Thr Asn Ile Leu Asp Pro Ser Tyr His Ile Pro Pro
                 530                 535                 540

 Leu Arg Glu Arg Leu Tyr Gly Arg Leu Thr Gln Ile Lys Gly Leu
                 545                 550                 555

 Phe Gln Lys Glu Gln Pro Ala Gly Glu Arg Thr Pro Leu Leu Leu
                 560                 565                 570

<210> 5839
<211> 1240
<212> DNA
<213> Homo sapien

<400> 5839
 tgcgcgtgcg cagggataag agagcggtct ggacagcgcg tggccggcgc 50

 cgctgtgggg acagcatgag cggcggttgg atggcgcagg ttggagcgtg 100

 gcgaacaggg gctctgggcc tggcgctgct gctgctgctc ggcctcggac 150

 taggcctgga ggccgccgcg agcccgcttt ccaccccgac ctctgcccag 200

 gccgcaggcc ccagctcagg ctcgtgccca cccaccaagt tccagtgccg 250

 caccagtggc ttatgcgtgc ccctcacctg gcgctgcgac agggacttgg 300

 actgcagcga tggcagcgat gaggaggagt gcaggattga gccatgtacc 350

 cagaaagggc aatgcccacc gccccctggc ctcccctgcc cctgcaccgg 400

 cgtcagtgac tgctctgggg gaactgacaa gaaactgcgc aactgcagcc 450

 gcctggcctg cctagcaggc gagctccgtt gcacgctgag cgatgactgc 500

 attccactca cgtggcgctg cgacggccac ccagactgtc ccgactccag 550

 cgacgagctc ggctgtggaa ccaatgagat cctcccggaa ggggatgcca 600

 caaccatggg gccccctgtg accctggaga gtgtcacctc tctcaggaat 650

 gccacaacca tggggccccc tgtgaccctg gagagtgtcc cctctgtcgg 700

 gaatgccaca tcctcctctg ccggagacca gtctggaagc ccaactgcct 750

 atggggttat tgcagctgct gcggtgctca gtgcaagcct ggtcaccgcc 800

 accctcctcc ttttgtcctg gctccgagcc caggagcgcc tccgcccact 850

 ggggttactg gtggccatga aggagtccct gctgctgtca gaacagaaga 900

 cctcgctgcc ctgaggacaa gcacttgcca ccaccgtcac tcagccctgg 950

 gcgtagccgg acaggaggag agcagtgatg cggatgggta cccgggcaca 1000

 ccagccctca gagacctgag ctcttctggc cacgtggaac ctcgaacccg 1050

 agctcctgca gaagtggccc tggagattga gggtccctgg acactcccta 1100

 tggagatccg gggagctagg atggggaacc tgccacagcc agaactgagg 1150

 ggctggcccc aggcagctcc cagggggtag aacggccctg tgcttaagac 1200

 actcctgctg ccccgtctga gggtggcgat taaagttgct 1240

<210> 5840
<211> 282
<212> PRT
<213> Homo sapien

<400> 5840
 Met Ser Gly Gly Trp Met Ala Gln Val Gly Ala Trp Arg Thr Gly
   1               5                  10                  15

 Ala Leu Gly Leu Ala Leu Leu Leu Leu Leu Gly Leu Gly Leu Gly
                  20                  25                  30

 Leu Glu Ala Ala Ala Ser Pro Leu Ser Thr Pro Thr Ser Ala Gln
                  35                  40                  45

 Ala Ala Gly Pro Ser Ser Gly Ser Cys Pro Pro Thr Lys Phe Gln
                  50                  55                  60

 Cys Arg Thr Ser Gly Leu Cys Val Pro Leu Thr Trp Arg Cys Asp
                  65                  70                  75

 Arg Asp Leu Asp Cys Ser Asp Gly Ser Asp Glu Glu Glu Cys Arg
                  80                  85                  90

 Ile Glu Pro Cys Thr Gln Lys Gly Gln Cys Pro Pro Pro Pro Gly
                  95                 100                 105

 Leu Pro Cys Pro Cys Thr Gly Val Ser Asp Cys Ser Gly Gly Thr
                 110                 115                 120

 Asp Lys Lys Leu Arg Asn Cys Ser Arg Leu Ala Cys Leu Ala Gly
                 125                 130                 135

 Glu Leu Arg Cys Thr Leu Ser Asp Asp Cys Ile Pro Leu Thr Trp
                 140                 145                 150

 Arg Cys Asp Gly His Pro Asp Cys Pro Asp Ser Ser Asp Glu Leu
                 155                 160                 165

 Gly Cys Gly Thr Asn Glu Ile Leu Pro Glu Gly Asp Ala Thr Thr
                 170                 175                 180

 Met Gly Pro Pro Val Thr Leu Glu Ser Val Thr Ser Leu Arg Asn
                 185                 190                 195

 Ala Thr Thr Met Gly Pro Pro Val Thr Leu Glu Ser Val Pro Ser
                 200                 205                 210

 Val Gly Asn Ala Thr Ser Ser Ser Ala Gly Asp Gln Ser Gly Ser
                 215                 220                 225

 Pro Thr Ala Tyr Gly Val Ile Ala Ala Ala Ala Val Leu Ser Ala
                 230                 235                 240

 Ser Leu Val Thr Ala Thr Leu Leu Leu Leu Ser Trp Leu Arg Ala
                 245                 250                 255

 Gln Glu Arg Leu Arg Pro Leu Gly Leu Leu Val Ala Met Lys Glu
                 260                 265                 270

 Ser Leu Leu Leu Ser Glu Gln Lys Thr Ser Leu Pro
                 275                 280

<210> 5841
<211> 1589
<212> DNA
<213> Homo sapien

<400> 5841
 gtctcttcct cgctccctct ctttctctcc tccctctgcc ttcccagtgc 50

 ataaagtctc tgtcgctccc ggaacttgtt ggcaatgcct attttttggc 100

 tttcccccgc gttctctaaa ctaactattt aaaggtctgc ggtcgcaaat 150

 ggtttgacta aacgtaggat gggacttaag ttgaacggca gatatatttc 200

 actgatcctc gcggtgcaaa tagcgtatct ggtgcaggcc gtgagagcag 250

 cgggcaagtg cgatgcggtc ttcaagggct tttcggactg tttgctcaag 300

 ctgggcgaca gcatggccaa ctacccgcag ggcctggacg acaagacgaa 350

 catcaagacc gtgtgcacat actgggagga tttccacagc tgcacggtca 400

 cagcccttac ggattgccag gaaggggcga aagatatgtg ggataaactg 450

 agaaaagaat ccaaaaacct caacatccaa ggcagcttat tcgaactctg 500

 cggcagcggc aacggggcgg cggggtccct gctcccggcg ttcccggtgc 550

 tcctggtgtc tctctcggca gctttagcga cctggctttc cttctgagcg 600

 tggggccagc tccccccgcg cgcccaccca cactcactcc atgctcccgg 650

 aaatcgagag gaagatccat tagttctttg gggacgttgt gattctctgt 700

 gatgctgaaa acactcatat aggattgtgg gaaatcctga ttctcttttt 750

 tatttcgttt gatttcttgt gttttatttg ccaaatgtta ccaatcagtg 800

 agcaagcaag cacagccaaa atcggacctc agctttagtc cgtcttcaca 850

 cacaaataag aaaacggcaa acccacccca ttttttaatt ttattattat 900

 taattttttt tgttggcaaa agaatctcag gaacggccct gggccaccta 950

 ctatattaat catgctagta acatgaaaaa tgatgggctc ctcctaatag 1000

 gaaggcgagg agaggagaag gccaggggaa tgaattcaag agagatgtcc 1050

 acggccgaaa catacggtga ataattcacg ctcacgtcgt tcttccacag 1100

 tatcttgttt tgatcatttc cactgcacat ttctcctcaa gaaaagcgaa 1150

 aggacagact gttggctttg tgtttggagg ataggaggga gagagggaag 1200

 gggctgagga aatctctggg gtaagagtaa aggcttccag aagacatgct 1250

 gctatggtca ctgaggggtt agctttatct gctgttgttg atgcatccgt 1300

 ccaagttcac tgcctttatt ttccctcctc cctcttgttt tagctgttac 1350

 acacacagta atacctgaat atccaacggt atagatcaca agggggggat 1400

 gttaaatgtt aatctaaaat atagctaaaa aaagattttg acataaaaga 1450

 gccttgattt taaaaaaaaa agagagagag atgtaattta aaaagtttat 1500

 tataaattaa attcagcaaa aaaagatttg ctacaaagta tagagaagta 1550

 taaaataaaa gttattgttt gaaaaaaaaa aaaaaaaaa 1589

<210> 5842
<211> 142
<212> PRT
<213> Homo sapien

<400> 5842
 Met Gly Leu Lys Leu Asn Gly Arg Tyr Ile Ser Leu Ile Leu Ala
   1               5                  10                  15

 Val Gln Ile Ala Tyr Leu Val Gln Ala Val Arg Ala Ala Gly Lys
                  20                  25                  30

 Cys Asp Ala Val Phe Lys Gly Phe Ser Asp Cys Leu Leu Lys Leu
                  35                  40                  45

 Gly Asp Ser Met Ala Asn Tyr Pro Gln Gly Leu Asp Asp Lys Thr
                  50                  55                  60

 Asn Ile Lys Thr Val Cys Thr Tyr Trp Glu Asp Phe His Ser Cys
                  65                  70                  75

 Thr Val Thr Ala Leu Thr Asp Cys Gln Glu Gly Ala Lys Asp Met
                  80                  85                  90

 Trp Asp Lys Leu Arg Lys Glu Ser Lys Asn Leu Asn Ile Gln Gly
                  95                 100                 105

 Ser Leu Phe Glu Leu Cys Gly Ser Gly Asn Gly Ala Ala Gly Ser
                 110                 115                 120

 Leu Leu Pro Ala Phe Pro Val Leu Leu Val Ser Leu Ser Ala Ala
                 125                 130                 135

 Leu Ala Thr Trp Leu Ser Phe
                 140

<210> 5843
<211> 760
<212> DNA
<213> Homo sapien

<400> 5843
 gagttttcat ttgtggtgag attctctccc aggccacaag acatttcctg 50

 ctcggaacct tgtttactaa tttccactgc ttttaaggcc ctgcactgaa 100

 aatgcaagct caggcgccgg tggtcgttgt gacccaacct ggagtcggtc 150

 ccggtccggc cccccagaac tccaactggc agacaggcat gtgtgactgt 200

 ttcagcgact gcggagtctg tctctgtggc acattttgtt tcccgtgcct 250

 tgggtgtcaa gttgcagctg atatgaatga atgctgtctg tgtggaacaa 300

 gcgtcgcaat gaggactctc tacaggaccc gatatggcat ccctggatct 350

 atttgtgatg actatatggc aactctttgc tgtcctcatt gtactctttg 400

 ccaaatcaag agagatatca acagaaggag agccatgcgt actttctaaa 450

 aactgatggt gaaaagctct taccgaagca acaaaattca gcagacacct 500

 cttcagcttg agttcttcac catcttttgc aactgaaata tgatggatat 550

 gcttaagtac aactgatggc atgaaaaaaa tcaaattttt gatttattat 600

 aaatgaatgt tgtccctgaa cttagctaaa tggtgcaact tagtttctcc 650

 ttgctttcat attatcgaat ttcctggctt ataaactttt taaattacat 700

 ttgaaatata aaccaaatga aatattttaa ctgataaaaa aaaaaaaaaa 750

 aaataaaaaa 760

<210> 5844
<211> 115
<212> PRT
<213> Homo sapien

<400> 5844
 Met Gln Ala Gln Ala Pro Val Val Val Val Thr Gln Pro Gly Val
   1               5                  10                  15

 Gly Pro Gly Pro Ala Pro Gln Asn Ser Asn Trp Gln Thr Gly Met
                  20                  25                  30

 Cys Asp Cys Phe Ser Asp Cys Gly Val Cys Leu Cys Gly Thr Phe
                  35                  40                  45

 Cys Phe Pro Cys Leu Gly Cys Gln Val Ala Ala Asp Met Asn Glu
                  50                  55                  60

 Cys Cys Leu Cys Gly Thr Ser Val Ala Met Arg Thr Leu Tyr Arg
                  65                  70                  75

 Thr Arg Tyr Gly Ile Pro Gly Ser Ile Cys Asp Asp Tyr Met Ala
                  80                  85                  90

 Thr Leu Cys Cys Pro His Cys Thr Leu Cys Gln Ile Lys Arg Asp
                  95                 100                 105

 Ile Asn Arg Arg Arg Ala Met Arg Thr Phe
                 110                 115

<210> 5845
<211> 2135
<212> DNA
<213> Homo sapien

<400> 5845
 gccccaggag cccggcgggt ccgggactcc cgtccgtgcc ggtgcgggcg 50

 ccggcatgtg gctgtgggag gaccagggcg gcctcctggg ccctttctcc 100

 ttcctgctgc tagtgctgct gctggtgacg cggagcccgg tcaatgcctg 150

 cctcctcacc ggcagcctct tcgttctact gcgcgtcttc agctttgagc 200

 cggtgccctc ttgcagggcc ctgcaggtgc tcaagccccg ggaccgcatt 250

 tctgccatcg cccaccgtgg cggcagccac gacgcgcccg agaacacgct 300

 ggcggccatt cggcaggcag ctaagaatgg agcaacaggc gtggagttgg 350

 acattgagtt tacttctgac gggattcctg tcttaatgca cgataacaca 400

 gtagatagga cgactgatgg gactgggcga ttgtgtgatt tgacatttga 450

 acaaattagg aagctgaatc ctgcagcaaa ccacagactc aggaatgatt 500

 tccctgatga aaagatccct accctaaggg aagctgttgc agagtgccta 550

 aaccataacc tcacaatctt ctttgatgtc aaaggccatg cacacaaggc 600

 tactgaggct ctaaagaaaa tgtatatgga atttcctcaa ctgtataata 650

 atagtgtggt ctgttctttc ttgccagaag ttatctacaa gatgagacaa 700

 acagatcggg atgtaataac agcattaact cacagacctt ggagcctaag 750

 ccatacagga gatgggaaac cacgctatga tactttctgg aaacatttta 800

 tatttgttat gatggacatt ttgctcgatt ggagcatgca taatatcttg 850

 tggtacctgt gtggaatttc agctttcctc atgcaaaagg attttgtatc 900

 cccggcctac ttgaagaagt ggtcagctaa aggaatccag gttgttggtt 950

 ggactgttaa tacctttgat gaaaagagtt actacgaatc ccatcttggt 1000

 tccagctata tcactgacag catggtagaa gactgcgaac ctcacttcta 1050

 gactttcacg gtgggacgaa acgggttcag aaactgccag gggcctcata 1100

 cagggatatc aaaataccct ttgtgctagc ccaggccctg gggaatcagg 1150

 tgactcacac aaatgcaata gttggtcact gcatttttac ctgaaccaaa 1200

 gctaaacccg gtgttgccac catgcaccat ggcatgccag agttcaacac 1250

 tgttgctctt gaaaatctgg gtctgaaaaa acgcacaaga gcccctgccc 1300

 tgccctagct gaggcacaca gggagaccca gtgaggataa gcacagattg 1350

 aattgtacaa tttgcagatg cagatgtaaa tgcatgggac atgcatgata 1400

 actcagagtt gacattttaa aacttgccac acttatttca aatatttgta 1450

 ctcagctatg ttaacatgta ctgtagacat caaacttgtg gccatactaa 1500

 taaaattatt aaaaggagca ctaaaggaaa actgtgtgcc aagcatcata 1550

 tcctaaggca tacggaattt ggggaagcca ccatgcaatc cagtgaggct 1600

 tcagtgtaca gcaaccaaaa tggtagggag gtcttgaagc caatgaggga 1650

 tttatagcat cttgaataga gagctgcaaa ccaccagggg gcagagttgc 1700

 acttttccag gctttttagg aagctctgca acagatgtga tctgatcata 1750

 ggcaattaga actggaagaa acttccaaaa atatctaggt ttgtcctcat 1800

 tttacaaatg aggaaactaa actctgtgga agggaagggg ttgcctcaaa 1850

 agtcacagct tagctgggca cagtggctca tgccgataat cccagcaatt 1900

 cagaaagctg aggcaggagg attacttgag gccagactgg gcaatatagc 1950

 aagaccccat ctctaaaaaa ttaggcatgg tggtgcatgc ctgtattccc 2000

 agctactcag gaggttgagg tgggaggatc acttgagccc agaagttcaa 2050

 ggctgcaatg agccatgatt acaccacggc actacaacct tggtggcaca 2100

 gtgagaacct gactcttaaa aaaaaaaaaa aaaaa 2135

<210> 5846
<211> 331
<212> PRT
<213> Homo sapien

<400> 5846
 Met Trp Leu Trp Glu Asp Gln Gly Gly Leu Leu Gly Pro Phe Ser
   1               5                  10                  15

 Phe Leu Leu Leu Val Leu Leu Leu Val Thr Arg Ser Pro Val Asn
                  20                  25                  30

 Ala Cys Leu Leu Thr Gly Ser Leu Phe Val Leu Leu Arg Val Phe
                  35                  40                  45

 Ser Phe Glu Pro Val Pro Ser Cys Arg Ala Leu Gln Val Leu Lys
                  50                  55                  60

 Pro Arg Asp Arg Ile Ser Ala Ile Ala His Arg Gly Gly Ser His
                  65                  70                  75

 Asp Ala Pro Glu Asn Thr Leu Ala Ala Ile Arg Gln Ala Ala Lys
                  80                  85                  90

 Asn Gly Ala Thr Gly Val Glu Leu Asp Ile Glu Phe Thr Ser Asp
                  95                 100                 105

 Gly Ile Pro Val Leu Met His Asp Asn Thr Val Asp Arg Thr Thr
                 110                 115                 120

 Asp Gly Thr Gly Arg Leu Cys Asp Leu Thr Phe Glu Gln Ile Arg
                 125                 130                 135

 Lys Leu Asn Pro Ala Ala Asn His Arg Leu Arg Asn Asp Phe Pro
                 140                 145                 150

 Asp Glu Lys Ile Pro Thr Leu Arg Glu Ala Val Ala Glu Cys Leu
                 155                 160                 165

 Asn His Asn Leu Thr Ile Phe Phe Asp Val Lys Gly His Ala His
                 170                 175                 180

 Lys Ala Thr Glu Ala Leu Lys Lys Met Tyr Met Glu Phe Pro Gln
                 185                 190                 195

 Leu Tyr Asn Asn Ser Val Val Cys Ser Phe Leu Pro Glu Val Ile
                 200                 205                 210

 Tyr Lys Met Arg Gln Thr Asp Arg Asp Val Ile Thr Ala Leu Thr
                 215                 220                 225

 His Arg Pro Trp Ser Leu Ser His Thr Gly Asp Gly Lys Pro Arg
                 230                 235                 240

 Tyr Asp Thr Phe Trp Lys His Phe Ile Phe Val Met Met Asp Ile
                 245                 250                 255

 Leu Leu Asp Trp Ser Met His Asn Ile Leu Trp Tyr Leu Cys Gly
                 260                 265                 270

 Ile Ser Ala Phe Leu Met Gln Lys Asp Phe Val Ser Pro Ala Tyr
                 275                 280                 285

 Leu Lys Lys Trp Ser Ala Lys Gly Ile Gln Val Val Gly Trp Thr
                 290                 295                 300

 Val Asn Thr Phe Asp Glu Lys Ser Tyr Tyr Glu Ser His Leu Gly
                 305                 310                 315

 Ser Ser Tyr Ile Thr Asp Ser Met Val Glu Asp Cys Glu Pro His
                 320                 325                 330

 Phe


<210> 5847
<211> 2427
<212> DNA
<213> Homo sapien

<400> 5847
 gggatttgtt attgcgaatg atgtggacaa caagcgctgc tacctgctcg 50

 tccatcaagc caagaggctg agcagcccct gcatcatggt ggtcaaccat 100

 gatgcctcca gcatacccag gctccagata gatgtggacg gcaggaaaga 150

 gatcctcttc tatgatcgaa ttttatgtga tgtcccttgc agtggagacg 200

 gcactatgag aaaaaacatt gatgtttgga aaaagtggac caccttaaat 250

 agcttgcagc tacatggctt acagctgcgg attgcaacac gcggggctga 300

 acagctggct gaaggtggaa gggtggtgta ttccacgtgt tcactaaacc 350

 ctattgagga tgaagcagtc atagcatctt tactggaaaa aagtgaaggt 400

 gctttggagc ttgctgatgt gtctaatgaa ctgccagggc tgaagtggat 450

 gcctggaatc acacagtgga aggtaatgac gaaagatggg cagtggttta 500

 cagactggga cgctgttcct cacagcagac acacccagat ccgacctacc 550

 atgttccctc cgaaggaccc agaaaagctg caggccatgc acctggagcg 600

 atgccttagg atattacccc atcatcagaa tactggaggg ttttttgtgg 650

 cagtattggt gaaaaaatct tcaatgccgt ggaataaacg tcagccaaag 700

 cttcagggta aatctgcaga gaccagagaa agcacacagc tgagccctgc 750

 agatctcaca gaagggaaac ccacagatcc ctctaagctg gaaagtccgt 800

 cattcacagg aactggtgac acagaaatag ctcatgcaac tgaggattta 850

 gagaataatg gcagtaagaa agatggcgtg tgtggtcctc ctccatcaaa 900

 gaaaatgaag ttatttggat ttaaagaaga tccatttgta tttattcctg 950

 aagatgaccc attatttcca cctattgaga aattttatgc tttggatcct 1000

 tcattcccaa ggatgaattt gttaactcgg actacagaag ggaagaaaag 1050

 gcagctctac atggtttcta aggagttgcg gaatgtgctg ctgaataaca 1100

 gtgagaagat gaaggttatt aacacgggga tcaaagtctg gtgtagaaat 1150

 aacagcggtg aagagtttga ctgtgctttc cggctggcac aggagggaat 1200

 atatacattg tatccattta ttaactcaag aattattact gtatcaatgg 1250

 aagatgttaa gatactgttg acccaggaaa atcccttttt tagaaaactc 1300

 agcagtgaga cctacagtca agcaaaggac ctggcaaagg gaagcatcgt 1350

 gctgaagtat gaaccagatt ctgcgaatcc agacgctcta cagtgtccca 1400

 tcgtcttatg cggatggcgg ggaaaggcct ccattcgaac ttttgtgccc 1450

 aagaatgaac ggcttcacta tctcaggatg atggggctgg aggtattggg 1500

 agaaaagaag aaggaagggg ttatcctcac aaatgagagt gcagccagca 1550

 ccggacagcc agacaatgac gtgactgagg gacagagagc aggagagccc 1600

 aacagcccag atgcagaaga ggccaacagt ccagacgtga cagcaggctg 1650

 tgacccggcg ggggtccatc caccccggtg agcaggccca aggcagcggg 1700

 ggcccacacc cctcacacgc aaaactggct tcttctggtc actggtgtct 1750

 gaaaccaaat ccagagcagc ctgtggcctg taaagcatat atttctagtg 1800

 actgcagact ggtgggatca taggagcctt ctgaatgacc aggactgctt 1850

 tctttggagc tgatgaaaat gtactctttt agcgtgttag aaatcacttg 1900

 ttttattttg ttttctttgg ccaagctggg tctagtgttt cttttgctgg 1950

 gaatagactt tcaaaagttg tacttctatc aagaaacaaa actgcccttg 2000

 cagaaatttc aggtcttttg ttaagcctgt attggtctta aggtgcagta 2050

 ttttttaaat tattatttat agaaagaatc tataaattct tggggaagtg 2100

 tgttataagc tttaataatt acattgagct gcacctcagt ggtgtgtcat 2150

 taacatgcag tggggttaat atctgaggcc tcagatgact ttgtgccttt 2200

 tggaataaag ggtaaaataa actctcccag agtaagagct gtatcgtgaa 2250

 ttgtcatact aattattgag ggggacttat gtgcttttat tgaatggagt 2300

 gctttacaat ttttattttt aaatggggtt gggatccttg gaatatttca 2350

 ataaaattga taaaatataa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2400

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 2427

<210> 5848
<211> 531
<212> PRT
<213> Homo sapien

<400> 5848
 Met Val Val Asn His Asp Ala Ser Ser Ile Pro Arg Leu Gln Ile
   1               5                  10                  15

 Asp Val Asp Gly Arg Lys Glu Ile Leu Phe Tyr Asp Arg Ile Leu
                  20                  25                  30

 Cys Asp Val Pro Cys Ser Gly Asp Gly Thr Met Arg Lys Asn Ile
                  35                  40                  45

 Asp Val Trp Lys Lys Trp Thr Thr Leu Asn Ser Leu Gln Leu His
                  50                  55                  60

 Gly Leu Gln Leu Arg Ile Ala Thr Arg Gly Ala Glu Gln Leu Ala
                  65                  70                  75

 Glu Gly Gly Arg Val Val Tyr Ser Thr Cys Ser Leu Asn Pro Ile
                  80                  85                  90

 Glu Asp Glu Ala Val Ile Ala Ser Leu Leu Glu Lys Ser Glu Gly
                  95                 100                 105

 Ala Leu Glu Leu Ala Asp Val Ser Asn Glu Leu Pro Gly Leu Lys
                 110                 115                 120

 Trp Met Pro Gly Ile Thr Gln Trp Lys Val Met Thr Lys Asp Gly
                 125                 130                 135

 Gln Trp Phe Thr Asp Trp Asp Ala Val Pro His Ser Arg His Thr
                 140                 145                 150

 Gln Ile Arg Pro Thr Met Phe Pro Pro Lys Asp Pro Glu Lys Leu
                 155                 160                 165

 Gln Ala Met His Leu Glu Arg Cys Leu Arg Ile Leu Pro His His
                 170                 175                 180

 Gln Asn Thr Gly Gly Phe Phe Val Ala Val Leu Val Lys Lys Ser
                 185                 190                 195

 Ser Met Pro Trp Asn Lys Arg Gln Pro Lys Leu Gln Gly Lys Ser
                 200                 205                 210

 Ala Glu Thr Arg Glu Ser Thr Gln Leu Ser Pro Ala Asp Leu Thr
                 215                 220                 225

 Glu Gly Lys Pro Thr Asp Pro Ser Lys Leu Glu Ser Pro Ser Phe
                 230                 235                 240

 Thr Gly Thr Gly Asp Thr Glu Ile Ala His Ala Thr Glu Asp Leu
                 245                 250                 255

 Glu Asn Asn Gly Ser Lys Lys Asp Gly Val Cys Gly Pro Pro Pro
                 260                 265                 270

 Ser Lys Lys Met Lys Leu Phe Gly Phe Lys Glu Asp Pro Phe Val
                 275                 280                 285

 Phe Ile Pro Glu Asp Asp Pro Leu Phe Pro Pro Ile Glu Lys Phe
                 290                 295                 300

 Tyr Ala Leu Asp Pro Ser Phe Pro Arg Met Asn Leu Leu Thr Arg
                 305                 310                 315

 Thr Thr Glu Gly Lys Lys Arg Gln Leu Tyr Met Val Ser Lys Glu
                 320                 325                 330

 Leu Arg Asn Val Leu Leu Asn Asn Ser Glu Lys Met Lys Val Ile
                 335                 340                 345

 Asn Thr Gly Ile Lys Val Trp Cys Arg Asn Asn Ser Gly Glu Glu
                 350                 355                 360

 Phe Asp Cys Ala Phe Arg Leu Ala Gln Glu Gly Ile Tyr Thr Leu
                 365                 370                 375

 Tyr Pro Phe Ile Asn Ser Arg Ile Ile Thr Val Ser Met Glu Asp
                 380                 385                 390

 Val Lys Ile Leu Leu Thr Gln Glu Asn Pro Phe Phe Arg Lys Leu
                 395                 400                 405

 Ser Ser Glu Thr Tyr Ser Gln Ala Lys Asp Leu Ala Lys Gly Ser
                 410                 415                 420

 Ile Val Leu Lys Tyr Glu Pro Asp Ser Ala Asn Pro Asp Ala Leu
                 425                 430                 435

 Gln Cys Pro Ile Val Leu Cys Gly Trp Arg Gly Lys Ala Ser Ile
                 440                 445                 450

 Arg Thr Phe Val Pro Lys Asn Glu Arg Leu His Tyr Leu Arg Met
                 455                 460                 465

 Met Gly Leu Glu Val Leu Gly Glu Lys Lys Lys Glu Gly Val Ile
                 470                 475                 480

 Leu Thr Asn Glu Ser Ala Ala Ser Thr Gly Gln Pro Asp Asn Asp
                 485                 490                 495

 Val Thr Glu Gly Gln Arg Ala Gly Glu Pro Asn Ser Pro Asp Ala
                 500                 505                 510

 Glu Glu Ala Asn Ser Pro Asp Val Thr Ala Gly Cys Asp Pro Ala
                 515                 520                 525

 Gly Val His Pro Pro Arg
                 530

<210> 5849
<211> 1554
<212> DNA
<213> Homo sapien

<400> 5849
 aattatatat ttttactcta tgtttctcta catgtttttt tctttccgtt 50

 gctggcggaa gaggcacgtg cgctgctgaa tggagctggt cgctggttgc 100

 tacgagcagg tcctctttgg gttcgctgta cacccggagc ccaaggcttg 150

 cggcgaccac gagcaatgga ctcttgtggc tgacttcact caccatgctc 200

 acactgcctc cttgtcagca gtagctgtaa atagtcgttt tgtggtcact 250

 gggagcaaag atgaaacaat tcacatttat gacatgaaaa agaagattga 300

 gcatggggct ctagtgcatc acagtggtac aataacttgc ctgaaattct 350

 atggcaacag gcatttaatc agtggagcgg aagatggact catctgtatc 400

 tgggatgcaa agaaatggga atgcctgaag tcaattaaag ctcacaaagg 450

 acaggtgacc ttcctttcta ttcacccatc tggcaagttg gccctgtcgg 500

 ttggtacaga taaaacttta agaacgtgga atcttgtaga aggaagatca 550

 gcattcataa aaaatataaa acaaaatgct cacatagtag aatggtcccc 600

 aagaggagag cagtatgtag ttatcataca gaataaaata gacatctatc 650

 agcttgacac tgcatccatt agtggcacca tcacaaatga aaagagaatt 700

 tcctctgtta aatttctttc agagtctgtc cttgcagtgg ctggagatga 750

 agaagttata aggttttttg actgtgattc actagtgtgc ctctgcgaat 800

 ttaaagctca tgaaaacagg gtaaaggaca tgttcagttt tgaaattcca 850

 gagcatcatg ttattgtttc agcatcgagt gatggtttca tcaaaatgtg 900

 gaagcttaag caggataaga aagttccccc atctttactc tgtgaaataa 950

 acactaatgc caggctgacg tgtcttggag tgtggctaga caaagtggca 1000

 gacatgaaaa gccttcctcc agctgcagag ccttctcctg taagtaaaga 1050

 acagtccaaa attggcaaaa aggagcctgg tgacacagtg cacaaagaag 1100

 aaaagcggtc aaaacctaac acaaagaaac gcggtttaac aggtgacagt 1150

 aagaaagcaa caaaagaaag tggcctgata tcaaccaaga agaggaaaat 1200

 ggtagaaatg ttggaaaaga agaggaaaaa gaagaaaata aaaacaatgc 1250

 agtgaatcac agatgtctcc tgaaagaact cttttagatg aaatcattct 1300

 actcaaatgt accttaattt ttttttttcc ctgagtaaaa gcaagaaatt 1350

 tcttcctttg gaaaaaatat atatattaaa aaaccacttt tagatggttt 1400

 tttttaaaaa aaaaaaaaaa actggtaaaa ttacttttgg cagacagtgt 1450

 tttatgaatt atgtatcatg ttgatatata atatgttaat gtgtcatgta 1500

 atttttactt tgtacaaagc aaataaagat ctttctcaaa aaaaaaaaaa 1550

 aaaa 1554

<210> 5850
<211> 391
<212> PRT
<213> Homo sapien

<400> 5850
 Met Glu Leu Val Ala Gly Cys Tyr Glu Gln Val Leu Phe Gly Phe
   1               5                  10                  15

 Ala Val His Pro Glu Pro Lys Ala Cys Gly Asp His Glu Gln Trp
                  20                  25                  30

 Thr Leu Val Ala Asp Phe Thr His His Ala His Thr Ala Ser Leu
                  35                  40                  45

 Ser Ala Val Ala Val Asn Ser Arg Phe Val Val Thr Gly Ser Lys
                  50                  55                  60

 Asp Glu Thr Ile His Ile Tyr Asp Met Lys Lys Lys Ile Glu His
                  65                  70                  75

 Gly Ala Leu Val His His Ser Gly Thr Ile Thr Cys Leu Lys Phe
                  80                  85                  90

 Tyr Gly Asn Arg His Leu Ile Ser Gly Ala Glu Asp Gly Leu Ile
                  95                 100                 105

 Cys Ile Trp Asp Ala Lys Lys Trp Glu Cys Leu Lys Ser Ile Lys
                 110                 115                 120

 Ala His Lys Gly Gln Val Thr Phe Leu Ser Ile His Pro Ser Gly
                 125                 130                 135

 Lys Leu Ala Leu Ser Val Gly Thr Asp Lys Thr Leu Arg Thr Trp
                 140                 145                 150

 Asn Leu Val Glu Gly Arg Ser Ala Phe Ile Lys Asn Ile Lys Gln
                 155                 160                 165

 Asn Ala His Ile Val Glu Trp Ser Pro Arg Gly Glu Gln Tyr Val
                 170                 175                 180

 Val Ile Ile Gln Asn Lys Ile Asp Ile Tyr Gln Leu Asp Thr Ala
                 185                 190                 195

 Ser Ile Ser Gly Thr Ile Thr Asn Glu Lys Arg Ile Ser Ser Val
                 200                 205                 210

 Lys Phe Leu Ser Glu Ser Val Leu Ala Val Ala Gly Asp Glu Glu
                 215                 220                 225

 Val Ile Arg Phe Phe Asp Cys Asp Ser Leu Val Cys Leu Cys Glu
                 230                 235                 240

 Phe Lys Ala His Glu Asn Arg Val Lys Asp Met Phe Ser Phe Glu
                 245                 250                 255

 Ile Pro Glu His His Val Ile Val Ser Ala Ser Ser Asp Gly Phe
                 260                 265                 270

 Ile Lys Met Trp Lys Leu Lys Gln Asp Lys Lys Val Pro Pro Ser
                 275                 280                 285

 Leu Leu Cys Glu Ile Asn Thr Asn Ala Arg Leu Thr Cys Leu Gly
                 290                 295                 300

 Val Trp Leu Asp Lys Val Ala Asp Met Lys Ser Leu Pro Pro Ala
                 305                 310                 315

 Ala Glu Pro Ser Pro Val Ser Lys Glu Gln Ser Lys Ile Gly Lys
                 320                 325                 330

 Lys Glu Pro Gly Asp Thr Val His Lys Glu Glu Lys Arg Ser Lys
                 335                 340                 345

 Pro Asn Thr Lys Lys Arg Gly Leu Thr Gly Asp Ser Lys Lys Ala
                 350                 355                 360

 Thr Lys Glu Ser Gly Leu Ile Ser Thr Lys Lys Arg Lys Met Val
                 365                 370                 375

 Glu Met Leu Glu Lys Lys Arg Lys Lys Lys Lys Ile Lys Thr Met
                 380                 385                 390

 Gln


<210> 5851
<211> 2308
<212> DNA
<213> Homo sapien

<400> 5851
 agcaggtttc gaatgctctt tacttccttt gtggagcaaa agaaaaaagc 50

 aggagtattt gaacaaatca ctaagactca tggaacaatt attggcatta 100

 cttcagggat tgtcttggtc cttctcatta tttctatttt agtacaagtg 150

 aaacagcctc gaaaaaaggt catggcttgc aaaaccgctt ttaataaaac 200

 cgggttccaa gaagtgtttg atcctcctca ttatgaactg ttttcactaa 250

 gggacaaaga gatttctgca gacctggcag acttgtcgga agaattggac 300

 aactaccaga ggatgcggcg ctcctccacc gcctcccgct gcatccacga 350

 ccaccactgt gggtcgcagg cctccagcgt caaacaaagc aggaccaacc 400

 tcagttccat ggagcttcct ctccgaaatg actttgcaca accacagcca 450

 atgaaaacat ttaatagcac cttcaagaaa agtagttaca ctttcaaaca 500

 gggacatgag tgccctgagc aggccctgga agaccgagta atggaggaga 550

 ttccctgtga aatttatgtc agggggcgag aagattctgc acaagcatcc 600

 atatccattg acttctaatc ttctgctaat ggtgatgtga attcttaggg 650

 tgtgtacgta cgcagcctcc agggcaccat actgtttcca gcagccaacc 700

 cttttctccc atcacaacta cgaagacctt gatttaccgt taacctattg 750

 tatggtgatg tttttattct ctcaggcagt ctatatatgt taaaccaatc 800

 aaggaactta ctctattcag tggaaacaat aatcatctct attgcttggt 850

 gtcatttata ggaagcactg ccagttaaag agcattagaa gaggtggttg 900

 gatggagcca ggctcaggct gcctcttcgt tttagcaaca agaagactgc 950

 tcttgactga taacagctct gtcaatattt tgatgccaca ataaacttga 1000

 tttttcttta cattcctttt atttttcctt tctctaaatt taatttgttt 1050

 tataagccta tcgttttacc atttcatttt cttacataag tacaagtggt 1100

 taatgtacca catacttcag tataggcatt tgttcttgag tgtgtcaaaa 1150

 tacagctagt tactgtgcca attaagaccc agttgtattt cacccatctg 1200

 tttcttcttg gctaatctct gtacttctgc cttttaatta ctgggccctt 1250

 attccttatt ttctgtgaga aataatagat gatatgattt attacctttc 1300

 aattatattt ttctcagtta tactagaaaa tttcataatc ctgggatata 1350

 tgtaccattg tcagctatga ctaaaaattt gaaaaagata aaaatttcta 1400

 gcaagccttt gaagtttacc aagtatagtc acattcagtg acagcccatt 1450

 cattccagta aagaatcatt tcattcactt tgggagaggc ctataattac 1500

 atttatttgc aatgtttctc ttcgctagat tgttacatag ctcccattct 1550

 gttggttttg cttacagcat atggtaacca aggttagatg ccagttaaaa 1600

 ttccttagaa attggatgag ccttgagatt gcttcttaac tgggacatga 1650

 catttttcta gctcttatca agaataacaa cttccacttt tttttaaact 1700

 gcacttttga ctttttttat ggtataaaaa caataattta taaacataaa 1750

 agctcattgt gttttttaga cttttgatat tatttgatac tgtacaaact 1800

 ttattaaatc aagatgaaag acctacagga cagattcctt tcagtgttca 1850

 catcagtggc tttgtatgca aatatgctgt gttggacctg gacgctataa 1900

 cttattgtaa agaccttgga aatgtggaca taagctcttt ctttcctttt 1950

 gttactgtat ttagtttgtg ataaattttt cactgtgtga tatttatgct 2000

 ctaaatcact acacaaatcc catattaaaa tatacattgt acctgaccct 2050

 ttaatcatgt tatttatgcc accaaggttg tggatcttaa ggtatgtatg 2100

 gaaaggaact catttatcaa attgtaagta atacagacat gccatttaaa 2150

 agaggtaaat tcttgttttc tatattttgt tagtaaattc tcaatgaaat 2200

 aagttgaagt ttcactggat ttcattaact tttaaatatt acatatatgt 2250

 gttttctcag attagtgaaa attgtgacct taaatttaat acacatatac 2300

 tgcctcag 2308

<210> 5852
<211> 201
<212> PRT
<213> Homo sapien

<400> 5852
 Met Leu Phe Thr Ser Phe Val Glu Gln Lys Lys Lys Ala Gly Val
   1               5                  10                  15

 Phe Glu Gln Ile Thr Lys Thr His Gly Thr Ile Ile Gly Ile Thr
                  20                  25                  30

 Ser Gly Ile Val Leu Val Leu Leu Ile Ile Ser Ile Leu Val Gln
                  35                  40                  45

 Val Lys Gln Pro Arg Lys Lys Val Met Ala Cys Lys Thr Ala Phe
                  50                  55                  60

 Asn Lys Thr Gly Phe Gln Glu Val Phe Asp Pro Pro His Tyr Glu
                  65                  70                  75

 Leu Phe Ser Leu Arg Asp Lys Glu Ile Ser Ala Asp Leu Ala Asp
                  80                  85                  90

 Leu Ser Glu Glu Leu Asp Asn Tyr Gln Arg Met Arg Arg Ser Ser
                  95                 100                 105

 Thr Ala Ser Arg Cys Ile His Asp His His Cys Gly Ser Gln Ala
                 110                 115                 120

 Ser Ser Val Lys Gln Ser Arg Thr Asn Leu Ser Ser Met Glu Leu
                 125                 130                 135

 Pro Leu Arg Asn Asp Phe Ala Gln Pro Gln Pro Met Lys Thr Phe
                 140                 145                 150

 Asn Ser Thr Phe Lys Lys Ser Ser Tyr Thr Phe Lys Gln Gly His
                 155                 160                 165

 Glu Cys Pro Glu Gln Ala Leu Glu Asp Arg Val Met Glu Glu Ile
                 170                 175                 180

 Pro Cys Glu Ile Tyr Val Arg Gly Arg Glu Asp Ser Ala Gln Ala
                 185                 190                 195

 Ser Ile Ser Ile Asp Phe
                 200

<210> 5853
<211> 3760
<212> DNA
<213> Homo sapien

<400> 5853
 tttatattaa cccctgatga cttcactgta aaaacaaata tttctgaagt 50

 aaatgctgct actcttcttt tgggaataga gaatcaacat aaaataagtg 100

 ttcctagagc acctacaaaa gaggaaatgt ctctcagagc ttatactgct 150

 cggtgtaggt taaacagact acgtcgtgca gcatgccgtt tgtttacttc 200

 tgaaaaaatg gttaaagcta ttaaaaagct tgaaattgaa attgaagcta 250

 ggcggttaat tgttcgaaaa gatagacacc tatggaaaga tgtgggagaa 300

 cgtcagaaag tcctgaattg gctgttgtcc tacaatcctt tgtggcttcg 350

 aattggtcta gagacaactt atggagaact catatctttg gaagataaca 400

 gtgatgtcac agggttggct atgtttattc tgaatcgcct actttggaat 450

 cctgatatag cagctgagta tagacacccc actgttcctc acctgtatag 500

 agatggtcat gaagaagctt tgtccaagtt tacattgaaa aagttattgt 550

 tgttggtctg ttttcttgat tatgctaaaa tttccagact cattgatcat 600

 gatccttgtc tcttctgtaa agatgccgaa ttcaaggcta gtaaagaaat 650

 ccttttggct ttttcacgag atttcctaag tggtgaaggt gacctttccc 700

 gtcaccttgg cttattggga ttacctgtta accatgttca gacaccattt 750

 gatgaatttg attttgccgt tacaaatctt gccgtagact tgcaatgtgg 800

 agtgcgcctt gtgcgaacca tggaacttct cacacagaac tgggacctct 850

 caaagaaact caggattccg gcaataagtc gtcttcaaaa gatgcacaat 900

 gttgacattg ttcttcaagt tcttaaatca cgaggaattg aattaagtga 950

 tgagcatgga aatacaattc tatctaagga tattgtggat aggcacagag 1000

 aaaaaactct caggttgctt tggaaaatag cgtttgcttt tcaggtggat 1050

 atttccctta acttagatca attaaaggaa gaaattgcct ttctaaaaca 1100

 cacaaagagt ataaagaaaa caatatctct actatcatgc cattttgatg 1150

 atcttattaa taagaaaaaa ggcaaaaggg atagtggttc ctttgaacaa 1200

 tatagtgaaa acataaagtt attgatggat tgggtaaatg ctgtttgtgc 1250

 cttctataat aaaaaggtgg agaattttac agtgtctttc tcagacggcc 1300

 gtgtgttatg ttacctgatc caccattacc atccttgcta tgtgccattt 1350

 gacgctatat gtcagcgtac tactcaaact gtggaatgta cgcaaactgg 1400

 ttcagtggta ttaaattcat catctgaatc tgatgacagt tctctggata 1450

 tgtctcttaa agcatttgat catgaaaata cttcagagct atacaaagag 1500

 ctcctagaaa atgaaaagaa aaattttcac ttggttaggt ctgcagttag 1550

 agaccttggt ggaatacctg ctatgattaa tcattcagat atgtcaaata 1600

 caattccaga tgaaaaggtg gttattacct atttgtcatt tctttgtgca 1650

 aggcttttgg atcttcgtaa agaaataaga gctgctcgac tcatacaaac 1700

 aacatggaga aaatataaac taaaaacaga tctcaaacgc catcaggaga 1750

 gagagaaagc tgcaagaatt attcaattgg ctgtaatcaa ttttctagca 1800

 aaacaaagat tgagaaaaag agttaatgca gcactcgtca ttcagaaata 1850

 ttggcgaaga gtcttagcac agagaaaatt attaatgtta aaaaaggaaa 1900

 agctggaaaa agttcaaaat aaagcagcat cacttattca ggctatgtgg 1950

 aggagatata gagccaagaa atatttatgt aaagtgaaag ctgcctgcaa 2000

 gattcaagcc tggtatagat gttggagagc acacaaagaa tatctagcta 2050

 tattaaaagc tgttaaaatt attcaaggtt gcttctatac caaactagag 2100

 agaacacggt ttttgaatgt gagagcatca gcaattatca ttcagagaaa 2150

 atggagagct atacttcctg caaagatagc tcatgaacac ttcttaatga 2200

 taaaaagaca tcgagctgct tgtttgatcc aagcacatta tagaggatat 2250

 aaaggaaggc aggtctttct tcggcagaaa tctgctgctt tgatcataca 2300

 aaaatatata cgagccaggg aggctggaaa gcatgaaagg ataaaatata 2350

 ttgaatttaa aaaatctaca gttatcctac aagcactggt gcgtggttgg 2400

 ctagtacgaa aaagattttt agaacagaga gccaaaattc gacttcttca 2450

 cttcactgca gctgcatatt atcacctgaa tgctgttaga attcaaagag 2500

 cctataaact ttacctggct gtgaagaatg ctaacaagca ggttaattca 2550

 gtcatctgta ttcagagatg gtttcgagca agattacaag aaaagagatt 2600

 tattcagaaa tatcatagca tcaaaaagat tgagcatgaa ggtcaagaat 2650

 gtctgagcca gcgaaatagg gctgcatcag taatacagaa agcagtgcgc 2700

 cattttctcc tccgtaaaaa gcaggaaaaa ttcactagtg gaatcattaa 2750

 aattcaggca ttatggagag gctattcttg gaggaagaaa aatgattgta 2800

 caaaaattaa agctatacga ctaagtcttc aagttgttaa tagggagatt 2850

 cgagaagaaa acaaactcta caaaagaact gcacttgcac ttcattacct 2900

 tttgacatat aagcaccttt ctgccattct tgaggcctta aaacacctag 2950

 aggtagttac tagattgtct ccactttgtt gtgagaacat ggcccagagt 3000

 ggagcaattt ctaaaatatt tgttttgatc cgaagttgta atcgcagtat 3050

 tccttgtatg gaagtcatca gatatgctgt gcaagtcttg cttaatgtat 3100

 ctaagtatga gaaaactact tcagcagttt atgatgtaga aaattgtata 3150

 gatatactat tggagctttt gcagatatac cgagaaaagc ctggtaataa 3200

 agttgcagac aaaggcggaa gcatttttac aaaaacttgt tgtttgttgg 3250

 ctattttact gaagacaaca aatagagcct ctgatgtacg aagtaggtcc 3300

 aaagttgttg accgtattta cagtctctac aaacttacag ctcataaaca 3350

 taaaatgaat actgaaagaa tactttacaa gcaaaagaag aattcttcta 3400

 taagcattcc ttttatccca gaaacacctg taaggaccag aatagtttca 3450

 agacttaagc cagattgggt tttgagaaga gataacatgg aagaaatcac 3500

 aaatcccctg caagctattc aaatggtgat ggatacgctt ggcattcctt 3550

 attagtaaat gtaaacattt tcagtatgta tagtgtaaag aaatattaaa 3600

 gccaatcatg agtacgtaaa gtgatttttg ctctccgtgt acaactttta 3650

 aaatctgact ttgttttaaa aaaacataaa ctgttcatta cattcttcat 3700

 ttttatcatt tatagtttta tgcatgtaat aaactaatat gtcataaaaa 3750

 aaaaaaaaaa 3760

<210> 5854
<211> 1142
<212> PRT
<213> Homo sapien

<400> 5854
 Met Ser Leu Arg Ala Tyr Thr Ala Arg Cys Arg Leu Asn Arg Leu
   1               5                  10                  15

 Arg Arg Ala Ala Cys Arg Leu Phe Thr Ser Glu Lys Met Val Lys
                  20                  25                  30

 Ala Ile Lys Lys Leu Glu Ile Glu Ile Glu Ala Arg Arg Leu Ile
                  35                  40                  45

 Val Arg Lys Asp Arg His Leu Trp Lys Asp Val Gly Glu Arg Gln
                  50                  55                  60

 Lys Val Leu Asn Trp Leu Leu Ser Tyr Asn Pro Leu Trp Leu Arg
                  65                  70                  75

 Ile Gly Leu Glu Thr Thr Tyr Gly Glu Leu Ile Ser Leu Glu Asp
                  80                  85                  90

 Asn Ser Asp Val Thr Gly Leu Ala Met Phe Ile Leu Asn Arg Leu
                  95                 100                 105

 Leu Trp Asn Pro Asp Ile Ala Ala Glu Tyr Arg His Pro Thr Val
                 110                 115                 120

 Pro His Leu Tyr Arg Asp Gly His Glu Glu Ala Leu Ser Lys Phe
                 125                 130                 135

 Thr Leu Lys Lys Leu Leu Leu Leu Val Cys Phe Leu Asp Tyr Ala
                 140                 145                 150

 Lys Ile Ser Arg Leu Ile Asp His Asp Pro Cys Leu Phe Cys Lys
                 155                 160                 165

 Asp Ala Glu Phe Lys Ala Ser Lys Glu Ile Leu Leu Ala Phe Ser
                 170                 175                 180

 Arg Asp Phe Leu Ser Gly Glu Gly Asp Leu Ser Arg His Leu Gly
                 185                 190                 195

 Leu Leu Gly Leu Pro Val Asn His Val Gln Thr Pro Phe Asp Glu
                 200                 205                 210

 Phe Asp Phe Ala Val Thr Asn Leu Ala Val Asp Leu Gln Cys Gly
                 215                 220                 225

 Val Arg Leu Val Arg Thr Met Glu Leu Leu Thr Gln Asn Trp Asp
                 230                 235                 240

 Leu Ser Lys Lys Leu Arg Ile Pro Ala Ile Ser Arg Leu Gln Lys
                 245                 250                 255

 Met His Asn Val Asp Ile Val Leu Gln Val Leu Lys Ser Arg Gly
                 260                 265                 270

 Ile Glu Leu Ser Asp Glu His Gly Asn Thr Ile Leu Ser Lys Asp
                 275                 280                 285

 Ile Val Asp Arg His Arg Glu Lys Thr Leu Arg Leu Leu Trp Lys
                 290                 295                 300

 Ile Ala Phe Ala Phe Gln Val Asp Ile Ser Leu Asn Leu Asp Gln
                 305                 310                 315

 Leu Lys Glu Glu Ile Ala Phe Leu Lys His Thr Lys Ser Ile Lys
                 320                 325                 330

 Lys Thr Ile Ser Leu Leu Ser Cys His Phe Asp Asp Leu Ile Asn
                 335                 340                 345

 Lys Lys Lys Gly Lys Arg Asp Ser Gly Ser Phe Glu Gln Tyr Ser
                 350                 355                 360

 Glu Asn Ile Lys Leu Leu Met Asp Trp Val Asn Ala Val Cys Ala
                 365                 370                 375

 Phe Tyr Asn Lys Lys Val Glu Asn Phe Thr Val Ser Phe Ser Asp
                 380                 385                 390

 Gly Arg Val Leu Cys Tyr Leu Ile His His Tyr His Pro Cys Tyr
                 395                 400                 405

 Val Pro Phe Asp Ala Ile Cys Gln Arg Thr Thr Gln Thr Val Glu
                 410                 415                 420

 Cys Thr Gln Thr Gly Ser Val Val Leu Asn Ser Ser Ser Glu Ser
                 425                 430                 435

 Asp Asp Ser Ser Leu Asp Met Ser Leu Lys Ala Phe Asp His Glu
                 440                 445                 450

 Asn Thr Ser Glu Leu Tyr Lys Glu Leu Leu Glu Asn Glu Lys Lys
                 455                 460                 465

 Asn Phe His Leu Val Arg Ser Ala Val Arg Asp Leu Gly Gly Ile
                 470                 475                 480

 Pro Ala Met Ile Asn His Ser Asp Met Ser Asn Thr Ile Pro Asp
                 485                 490                 495

 Glu Lys Val Val Ile Thr Tyr Leu Ser Phe Leu Cys Ala Arg Leu
                 500                 505                 510

 Leu Asp Leu Arg Lys Glu Ile Arg Ala Ala Arg Leu Ile Gln Thr
                 515                 520                 525

 Thr Trp Arg Lys Tyr Lys Leu Lys Thr Asp Leu Lys Arg His Gln
                 530                 535                 540

 Glu Arg Glu Lys Ala Ala Arg Ile Ile Gln Leu Ala Val Ile Asn
                 545                 550                 555

 Phe Leu Ala Lys Gln Arg Leu Arg Lys Arg Val Asn Ala Ala Leu
                 560                 565                 570

 Val Ile Gln Lys Tyr Trp Arg Arg Val Leu Ala Gln Arg Lys Leu
                 575                 580                 585

 Leu Met Leu Lys Lys Glu Lys Leu Glu Lys Val Gln Asn Lys Ala
                 590                 595                 600

 Ala Ser Leu Ile Gln Ala Met Trp Arg Arg Tyr Arg Ala Lys Lys
                 605                 610                 615

 Tyr Leu Cys Lys Val Lys Ala Ala Cys Lys Ile Gln Ala Trp Tyr
                 620                 625                 630

 Arg Cys Trp Arg Ala His Lys Glu Tyr Leu Ala Ile Leu Lys Ala
                 635                 640                 645

 Val Lys Ile Ile Gln Gly Cys Phe Tyr Thr Lys Leu Glu Arg Thr
                 650                 655                 660

 Arg Phe Leu Asn Val Arg Ala Ser Ala Ile Ile Ile Gln Arg Lys
                 665                 670                 675

 Trp Arg Ala Ile Leu Pro Ala Lys Ile Ala His Glu His Phe Leu
                 680                 685                 690

 Met Ile Lys Arg His Arg Ala Ala Cys Leu Ile Gln Ala His Tyr
                 695                 700                 705

 Arg Gly Tyr Lys Gly Arg Gln Val Phe Leu Arg Gln Lys Ser Ala
                 710                 715                 720

 Ala Leu Ile Ile Gln Lys Tyr Ile Arg Ala Arg Glu Ala Gly Lys
                 725                 730                 735

 His Glu Arg Ile Lys Tyr Ile Glu Phe Lys Lys Ser Thr Val Ile
                 740                 745                 750

 Leu Gln Ala Leu Val Arg Gly Trp Leu Val Arg Lys Arg Phe Leu
                 755                 760                 765

 Glu Gln Arg Ala Lys Ile Arg Leu Leu His Phe Thr Ala Ala Ala
                 770                 775                 780

 Tyr Tyr His Leu Asn Ala Val Arg Ile Gln Arg Ala Tyr Lys Leu
                 785                 790                 795

 Tyr Leu Ala Val Lys Asn Ala Asn Lys Gln Val Asn Ser Val Ile
                 800                 805                 810

 Cys Ile Gln Arg Trp Phe Arg Ala Arg Leu Gln Glu Lys Arg Phe
                 815                 820                 825

 Ile Gln Lys Tyr His Ser Ile Lys Lys Ile Glu His Glu Gly Gln
                 830                 835                 840

 Glu Cys Leu Ser Gln Arg Asn Arg Ala Ala Ser Val Ile Gln Lys
                 845                 850                 855

 Ala Val Arg His Phe Leu Leu Arg Lys Lys Gln Glu Lys Phe Thr
                 860                 865                 870

 Ser Gly Ile Ile Lys Ile Gln Ala Leu Trp Arg Gly Tyr Ser Trp
                 875                 880                 885

 Arg Lys Lys Asn Asp Cys Thr Lys Ile Lys Ala Ile Arg Leu Ser
                 890                 895                 900

 Leu Gln Val Val Asn Arg Glu Ile Arg Glu Glu Asn Lys Leu Tyr
                 905                 910                 915

 Lys Arg Thr Ala Leu Ala Leu His Tyr Leu Leu Thr Tyr Lys His
                 920                 925                 930

 Leu Ser Ala Ile Leu Glu Ala Leu Lys His Leu Glu Val Val Thr
                 935                 940                 945

 Arg Leu Ser Pro Leu Cys Cys Glu Asn Met Ala Gln Ser Gly Ala
                 950                 955                 960

 Ile Ser Lys Ile Phe Val Leu Ile Arg Ser Cys Asn Arg Ser Ile
                 965                 970                 975

 Pro Cys Met Glu Val Ile Arg Tyr Ala Val Gln Val Leu Leu Asn
                 980                 985                 990

 Val Ser Lys Tyr Glu Lys Thr Thr Ser Ala Val Tyr Asp Val Glu
                 995                1000                1005

 Asn Cys Ile Asp Ile Leu Leu Glu Leu Leu Gln Ile Tyr Arg Glu
                1010                1015                1020

 Lys Pro Gly Asn Lys Val Ala Asp Lys Gly Gly Ser Ile Phe Thr
                1025                1030                1035

 Lys Thr Cys Cys Leu Leu Ala Ile Leu Leu Lys Thr Thr Asn Arg
                1040                1045                1050

 Ala Ser Asp Val Arg Ser Arg Ser Lys Val Val Asp Arg Ile Tyr
                1055                1060                1065

 Ser Leu Tyr Lys Leu Thr Ala His Lys His Lys Met Asn Thr Glu
                1070                1075                1080

 Arg Ile Leu Tyr Lys Gln Lys Lys Asn Ser Ser Ile Ser Ile Pro
                1085                1090                1095

 Phe Ile Pro Glu Thr Pro Val Arg Thr Arg Ile Val Ser Arg Leu
                1100                1105                1110

 Lys Pro Asp Trp Val Leu Arg Arg Asp Asn Met Glu Glu Ile Thr
                1115                1120                1125

 Asn Pro Leu Gln Ala Ile Gln Met Val Met Asp Thr Leu Gly Ile
                1130                1135                1140

 Pro Tyr


<210> 5855
<211> 1680
<212> DNA
<213> Homo sapien

<400> 5855
 agagagctgt ttactaggca cgactgcgaa ggcaaggggg caccagctca 50

 ggactgcatc tgcctgccat ttcccttcca ctcctccttt ctggagtctg 100

 acattagaaa gccagcgaga aggaagattc aaacaaccaa ccctgatttc 150

 ctgcttctcc ttttcatgag tgttcctgtg gtctctgcac ctcctttctg 200

 tcccccggca gagggcagta gagatggccg gcccaaggcc tcggtggcgc 250

 gaccagctgc tgttcatgag catcatagtc ctcgtgattg tggtcatctg 300

 cctgatgtta tacgctcttc tctgggaggc tggcaacctc actgacctgc 350

 ccaacctgag aatcggcttc tataacttct gcctgtggaa tgaggacacc 400

 agcaccctac agtgtcacca gttccctgag ctggaagccc tgggggtgcc 450

 tcgggttggc ctgggcctgg ccaggcttgg cgtgtacggg tccctggtcc 500

 tcaccctctt tgccccccag cctctcctcc tagcccagtg caacagtgat 550

 gagagagcgt ggcggctggc agtgggcttc ctggctgtgt cctctgtgct 600

 gctggcaggc ggcctgggcc tcttcctctc ctatgtgtgg aagtgggtca 650

 ggctctccct cccggggcct gggtttctag ctctgggcag cgcccaggcc 700

 ttactcatcc tcttgcttat agccatggct gtgttccctc tgagggctga 750

 gagggctgag agcaagcttg agagctgcta aaggcttacg tgattgcaag 800

 ggttcagttc caaccatagt cagaggtggc acatctgctc agccatctca 850

 ttttacagct aacgctgatc tccagctcca gcgatggaac ccactacaga 900

 ggaggtgggg cccctgtgtc aaagaggccg aggggcagca agggcagcca 950

 gggcacctgt gacttcttag tacaagattg tctgtccttc aggacttcca 1000

 aggctcccaa agactcccta aaccatgcag ctcattgtca caccaattcc 1050

 tgctttaatt aatggatctg agcaaatctt cctctagctt caggagggtg 1100

 gggagggagt gattgccgtc atggggccag acttccaggc tgatttgcca 1150

 aatgccaaaa tgaaacctag caaagaactt acggcaacaa acgaggacat 1200

 taaaagagcg agcacctcag tgtctctggg gacatggtta aggagcttcc 1250

 actcagccca ccatagtgag tgggccgcca taagccatca ctggaactcc 1300

 aaccccagag gtccaggagt gatctctgag tgactcaaca aagacaggac 1350

 acatggggta caaagacaag gcttgactgc ttcaaagctt ccctggacct 1400

 gaagccagac agggcagagg cgtccgctga caaatcactc ccatgatgag 1450

 accctggagg actccaaatc ctcgctgtga acaggactgg acggttgcgc 1500

 acaaacaaac gctgccaccc tccacttccc aacccagaac ttggaaagac 1550

 attagcacaa cttacgcatt ggggaattgt gtgtattttc tagcacttgt 1600

 gtattggaaa acctgtatgg cagtgattta ttcatatatt cctgtccaaa 1650

 gccacactga aaacagaggc agagacatgt 1680

<210> 5856
<211> 185
<212> PRT
<213> Homo sapien

<400> 5856
 Met Ala Gly Pro Arg Pro Arg Trp Arg Asp Gln Leu Leu Phe Met
   1               5                  10                  15

 Ser Ile Ile Val Leu Val Ile Val Val Ile Cys Leu Met Leu Tyr
                  20                  25                  30

 Ala Leu Leu Trp Glu Ala Gly Asn Leu Thr Asp Leu Pro Asn Leu
                  35                  40                  45

 Arg Ile Gly Phe Tyr Asn Phe Cys Leu Trp Asn Glu Asp Thr Ser
                  50                  55                  60

 Thr Leu Gln Cys His Gln Phe Pro Glu Leu Glu Ala Leu Gly Val
                  65                  70                  75

 Pro Arg Val Gly Leu Gly Leu Ala Arg Leu Gly Val Tyr Gly Ser
                  80                  85                  90

 Leu Val Leu Thr Leu Phe Ala Pro Gln Pro Leu Leu Leu Ala Gln
                  95                 100                 105

 Cys Asn Ser Asp Glu Arg Ala Trp Arg Leu Ala Val Gly Phe Leu
                 110                 115                 120

 Ala Val Ser Ser Val Leu Leu Ala Gly Gly Leu Gly Leu Phe Leu
                 125                 130                 135

 Ser Tyr Val Trp Lys Trp Val Arg Leu Ser Leu Pro Gly Pro Gly
                 140                 145                 150

 Phe Leu Ala Leu Gly Ser Ala Gln Ala Leu Leu Ile Leu Leu Leu
                 155                 160                 165

 Ile Ala Met Ala Val Phe Pro Leu Arg Ala Glu Arg Ala Glu Ser
                 170                 175                 180

 Lys Leu Glu Ser Cys
                 185

<210> 5857
<211> 1047
<212> DNA
<213> Homo sapien

<400> 5857
 ctgtgagtga cacacgctga gtggggtgaa gggaaatgct ggtgaatttc 50

 attttgaggt gtgggttgct gttagtcact ctgtctcttg ccattgccaa 100

 gcacaagcaa tcttccttca ccaaaagttg ttacccaagg ggaacattgt 150

 cccaagctgt tgacgctctc tatatcaaag cagcatggct caaagcaacg 200

 attccagaag accgcataaa aaatatacga ttattaaaaa agaaaacaaa 250

 aaagcagttt atgaaaaact gtcaatttca agaacagctt ctgtccttct 300

 tcatggaaga cgtttttggt caactgcaat tgcaaggctg caagaaaata 350

 cgctttgtgg aggactttca tagccttagg cagaaattga gccactgtat 400

 ttcctgtgct tcatcagcta gagagatgaa atccattacc aggatgaaaa 450

 gaatatttta taggattgga aacaaaggaa tctacaaagc catcagtgaa 500

 ctggatattc ttctttcctg gattaaaaaa ttattggaaa gcagtcagta 550

 aaccaaagcc aagtacattg attttacagt tattttgaaa tacaataaga 600

 actgctagaa atatgtttat aacagtctat ttcttttaaa aactttttaa 650

 cataatactg acggcatgtt aggtgattca gaatagacaa gaaggattta 700

 gtaaattaac gttttggata taagttgtca ctaatttgca cattttctgt 750

 gttttcaaat aatgtttcca ttctgaacat gttttgtcat tcacaagtac 800

 attgtgtcaa cttaatttaa agtatgtaac ctgaattaac tcgtgtaata 850

 tttgtgtgtg gagtgggatg tggggggtgg agggggaatg acagatttct 900

 ggaatgcaat gtaatgttac tgagacttaa atagatgtta tgtatatgat 950

 tgtctgttta agtgtttgaa aattgttaat tatgcccagt gtgaacttag 1000

 tacttaacac attttgattt taattaaata aattgggttt ccttctc 1047

<210> 5858
<211> 171
<212> PRT
<213> Homo sapien

<400> 5858
 Met Leu Val Asn Phe Ile Leu Arg Cys Gly Leu Leu Leu Val Thr
   1               5                  10                  15

 Leu Ser Leu Ala Ile Ala Lys His Lys Gln Ser Ser Phe Thr Lys
                  20                  25                  30

 Ser Cys Tyr Pro Arg Gly Thr Leu Ser Gln Ala Val Asp Ala Leu
                  35                  40                  45

 Tyr Ile Lys Ala Ala Trp Leu Lys Ala Thr Ile Pro Glu Asp Arg
                  50                  55                  60

 Ile Lys Asn Ile Arg Leu Leu Lys Lys Lys Thr Lys Lys Gln Phe
                  65                  70                  75

 Met Lys Asn Cys Gln Phe Gln Glu Gln Leu Leu Ser Phe Phe Met
                  80                  85                  90

 Glu Asp Val Phe Gly Gln Leu Gln Leu Gln Gly Cys Lys Lys Ile
                  95                 100                 105

 Arg Phe Val Glu Asp Phe His Ser Leu Arg Gln Lys Leu Ser His
                 110                 115                 120

 Cys Ile Ser Cys Ala Ser Ser Ala Arg Glu Met Lys Ser Ile Thr
                 125                 130                 135

 Arg Met Lys Arg Ile Phe Tyr Arg Ile Gly Asn Lys Gly Ile Tyr
                 140                 145                 150

 Lys Ala Ile Ser Glu Leu Asp Ile Leu Leu Ser Trp Ile Lys Lys
                 155                 160                 165

 Leu Leu Glu Ser Ser Gln
                 170

<210> 5859
<211> 636
<212> DNA
<213> Homo sapien

<400> 5859
 gatcgcggag tcggtgcttt agtacgccgc tggcaccttt actctcgccg 50

 gccgcgcgaa cccgtttgag ctcggtatcc tagtgcacac gcctttgcaa 100

 gcgacggcgc catgagtctg acttccagtt ccagcgtacg agttgaatgg 150

 atcgcagcag ttaccattgc tgctgggaca gctgcaattg gttatctagc 200

 ttacaaaaga ttttatgtta aagatcatcg aaataaagct atgataaacc 250

 ttcacatcca gaaagacaac cccaagatag tacatgcttt tgacatggag 300

 gatttgggag ataaagctgt gtactgccgt tgttggaggt ccaaaaagtt 350

 cccattctgt gatggggctc acacaaaaca taacgaagag actggagaca 400

 atgtgggccc tctgatcatc aagaaaaaag aaacttaaat ggacactttt 450

 gatgctgcaa atcagcttgt cgtgaagtta cctgattgtt taattagaat 500

 gactaccacc tctgtctgat tcaccttcgc tggattctaa atgtggtata 550

 ttgcaaactg cagctttcac atttatggca tttgtcttgt tgaaacatcg 600

 tggtgcacat ttgtttaaac aaaaaaaaaa aaaaaa 636

<210> 5860
<211> 108
<212> PRT
<213> Homo sapien

<400> 5860
 Met Ser Leu Thr Ser Ser Ser Ser Val Arg Val Glu Trp Ile Ala
   1               5                  10                  15

 Ala Val Thr Ile Ala Ala Gly Thr Ala Ala Ile Gly Tyr Leu Ala
                  20                  25                  30

 Tyr Lys Arg Phe Tyr Val Lys Asp His Arg Asn Lys Ala Met Ile
                  35                  40                  45

 Asn Leu His Ile Gln Lys Asp Asn Pro Lys Ile Val His Ala Phe
                  50                  55                  60

 Asp Met Glu Asp Leu Gly Asp Lys Ala Val Tyr Cys Arg Cys Trp
                  65                  70                  75

 Arg Ser Lys Lys Phe Pro Phe Cys Asp Gly Ala His Thr Lys His
                  80                  85                  90

 Asn Glu Glu Thr Gly Asp Asn Val Gly Pro Leu Ile Ile Lys Lys
                  95                 100                 105

 Lys Glu Thr


<210> 5861
<211> 1032
<212> DNA
<213> Homo sapien

<400> 5861
 ataacacaca tcacactgtt taagagtggg ggaaagaata gtcatactgt 50

 tagagcacaa tgtttcctga aaagaaactg atcaaaacgt ttgaagcctt 100

 tttagttgcc tcaaagtgtg acagccactc aatactgctc ctaacagtct 150

 gctttcagat aacgtcataa aataaaataa ctgtgtgaaa agccatggcc 200

 ttcaaaaaac tttatttggt tatgagccaa gctctgatag gaaaagccca 250

 cctacgaaaa aaaggtgtgg gtatttaagc tggtctgatt cacagagctt 300

 gtacattcat gactcaaaat aacacaccct caaacccaaa tgattctaaa 350

 gccatttcaa ccttaaatca tgttattccc ttagatgtgc ttacattagc 400

 tttaaaaaat gatctacgtg cagagaggag ctgcgccttc ctcacaatta 450

 attgaaacat gaccaaaaaa cggggcatag gcaaaaaagt gacatttaaa 500

 tagcgtatga gggtctctcc tcctttactc aatgaacaca tatccagaat 550

 gagattgaaa tggaatcaat gcccaggagc ctctcaaaga gagcatctcc 600

 ctgtagccaa catgatctgg atcctcctaa cacaaagcaa cccaactact 650

 ccagctacac aaagccagta ggcctacata tgaaacgcaa aggggttgca 700

 tcccccacgg tttaaaccta acccatgtta gctgcaactc cactacagtc 750

 ttgatcactt agctcaggaa acaaacaccc agcaacaacc ctcgtatctc 800

 attaatacca atctgtggcc ctcactgact cagtggtact tttttataaa 850

 aatatctgaa gaagtggcaa acggttacaa cggatgtcag gtcgaagcaa 900

 ttccaaaagc tgagaaaacg cttcatccgc tgcttgtctt ctccccctat 950

 tgctacagtt ctgccaccaa agggggaaaa ttacgtgaat atgattgttg 1000

 tgaccaagcc ttggcaaaag tcaataaata ac 1032

<210> 5862
<211> 1816
<212> DNA
<213> Homo sapien

<400> 5862
 gcacgagcga tgtcgctcgt gctgctaagc ctggccgcgc tgtgcaggag 50

 cgccgtaccc cgagagccga ccgttcaatg tggctctgaa actgggccat 100

 ctccagagtg gatgctacaa catgatctaa tccccggaga cttgagggac 150

 ctccgagtag aacctgttac aactagtgtt gcaacagggg actattcaat 200

 tttgatgaat gtaagctggg tactccgggc agatgccagc atccgcttgt 250

 tgaaggccac caagatttgt gtgacgggca aaagcaactt ccagtcctac 300

 agctgtgtga ggtgcaatta cacagaggcc ttccagactc agaccagacc 350

 ctctggtggt aaatggacat tttcctacat cggcttccct gtagagctga 400

 acacagtcta tttcattggg gcccataata ttcctaatgc aaatatgaat 450

 gaagatggcc cttccatgtc tgtgaatttc acctcaccag gctgcctaga 500

 ccacataatg aaatataaaa aaaagtgtgt caaggccgga agcctgtggg 550

 atccgaacat cactgcttgt aagaagaatg aggagacagt agaagtgaac 600

 ttcacaacca ctcccctggg aaacagatac atggctctta tccaacacag 650

 cactatcatc gggttttctc aggtgtttga gccacaccag aagaaacaaa 700

 cgcgagcttc agtggtgatt ccagtgactg gggatagtga aggtgctacg 750

 gtgcagctga ctccatattt tcctacttgt ggcagcgact gcatccgaca 800

 taaaggaaca gttgtgctct gcccacaaac aggcgtccct ttccctctgg 850

 ataacaacaa aagcaagccg ggaggctggc tgcctctcct cctgctgtct 900

 ctgctggtgg ccacatgggt gctggtggca gggatctatc taatgtggag 950

 gcacgaaagg atcaagaaga cttccttttc taccaccaca ctactgcccc 1000

 ccattaaggt tcttgtggtt tacccatctg aaatatgttt ccatcacaca 1050

 atttgttact tcactgaatt tcttcaaaac cattgcagaa gtgaggtcat 1100

 ccttgaaaag tggcagaaaa agaaaatagc agagatgggt ccagtgcagt 1150

 ggcttgccac tcaaaagaag gcagcagaca aagtcgtctt ccttctttcc 1200

 aatgacgtca acagtgtgtg cgatggtacc tgtggcaaga gcgagggcag 1250

 tcccagtgag aactctcaag actcttcccc ttgcctttaa ccttttctgc 1300

 agtgatctaa gaagccagat tcatctgcac aaatacgtgg tggtctactt 1350

 tagagagatt gatacaaaag acgattacaa tgctctcagt gtctgcccca 1400

 agtaccacct catgaaggat gccactgctt tctgtgcaga acttctccat 1450

 gtcaagtagc aggtgtcagc aggaaaaaga tcacaagcct gccacgatgg 1500

 ctgctgctcc ttgtagccca cccatgagaa gcaagagacc ttaaaggctt 1550

 cctatcccac caattacagg gaaaaaacgt gtgatgatcc tgaagcttac 1600

 tatgcagcct acaaacagcc ttagtaatta aaacatttta taccaataaa 1650

 attttcaaat attgctaact aatgtagcat taactaacga ttggaaacta 1700

 catttacaac ttcaaagctg ttttatacat agaaatcaat tacagtttta 1750

 attgaaaact ataaccattt tgataatgca acaataaagc atcttcagcc 1800

 aaaaaaaaaa aaaaaa 1816

<210> 5863
<211> 426
<212> PRT
<213> Homo sapien

<400> 5863
 Met Ser Leu Val Leu Leu Ser Leu Ala Ala Leu Cys Arg Ser Ala
   1               5                  10                  15

 Val Pro Arg Glu Pro Thr Val Gln Cys Gly Ser Glu Thr Gly Pro
                  20                  25                  30

 Ser Pro Glu Trp Met Leu Gln His Asp Leu Ile Pro Gly Asp Leu
                  35                  40                  45

 Arg Asp Leu Arg Val Glu Pro Val Thr Thr Ser Val Ala Thr Gly
                  50                  55                  60

 Asp Tyr Ser Ile Leu Met Asn Val Ser Trp Val Leu Arg Ala Asp
                  65                  70                  75

 Ala Ser Ile Arg Leu Leu Lys Ala Thr Lys Ile Cys Val Thr Gly
                  80                  85                  90

 Lys Ser Asn Phe Gln Ser Tyr Ser Cys Val Arg Cys Asn Tyr Thr
                  95                 100                 105

 Glu Ala Phe Gln Thr Gln Thr Arg Pro Ser Gly Gly Lys Trp Thr
                 110                 115                 120

 Phe Ser Tyr Ile Gly Phe Pro Val Glu Leu Asn Thr Val Tyr Phe
                 125                 130                 135

 Ile Gly Ala His Asn Ile Pro Asn Ala Asn Met Asn Glu Asp Gly
                 140                 145                 150

 Pro Ser Met Ser Val Asn Phe Thr Ser Pro Gly Cys Leu Asp His
                 155                 160                 165

 Ile Met Lys Tyr Lys Lys Lys Cys Val Lys Ala Gly Ser Leu Trp
                 170                 175                 180

 Asp Pro Asn Ile Thr Ala Cys Lys Lys Asn Glu Glu Thr Val Glu
                 185                 190                 195

 Val Asn Phe Thr Thr Thr Pro Leu Gly Asn Arg Tyr Met Ala Leu
                 200                 205                 210

 Ile Gln His Ser Thr Ile Ile Gly Phe Ser Gln Val Phe Glu Pro
                 215                 220                 225

 His Gln Lys Lys Gln Thr Arg Ala Ser Val Val Ile Pro Val Thr
                 230                 235                 240

 Gly Asp Ser Glu Gly Ala Thr Val Gln Leu Thr Pro Tyr Phe Pro
                 245                 250                 255

 Thr Cys Gly Ser Asp Cys Ile Arg His Lys Gly Thr Val Val Leu
                 260                 265                 270

 Cys Pro Gln Thr Gly Val Pro Phe Pro Leu Asp Asn Asn Lys Ser
                 275                 280                 285

 Lys Pro Gly Gly Trp Leu Pro Leu Leu Leu Leu Ser Leu Leu Val
                 290                 295                 300

 Ala Thr Trp Val Leu Val Ala Gly Ile Tyr Leu Met Trp Arg His
                 305                 310                 315

 Glu Arg Ile Lys Lys Thr Ser Phe Ser Thr Thr Thr Leu Leu Pro
                 320                 325                 330

 Pro Ile Lys Val Leu Val Val Tyr Pro Ser Glu Ile Cys Phe His
                 335                 340                 345

 His Thr Ile Cys Tyr Phe Thr Glu Phe Leu Gln Asn His Cys Arg
                 350                 355                 360

 Ser Glu Val Ile Leu Glu Lys Trp Gln Lys Lys Lys Ile Ala Glu
                 365                 370                 375

 Met Gly Pro Val Gln Trp Leu Ala Thr Gln Lys Lys Ala Ala Asp
                 380                 385                 390

 Lys Val Val Phe Leu Leu Ser Asn Asp Val Asn Ser Val Cys Asp
                 395                 400                 405

 Gly Thr Cys Gly Lys Ser Glu Gly Ser Pro Ser Glu Asn Ser Gln
                 410                 415                 420

 Asp Ser Ser Pro Cys Leu
                 425

<210> 5864
<211> 487
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 22
<223> Unknown base

<400> 5864
 ccgtgatgtg gcgcctgcac antcctttcc ctttcggatt cccgacgctg 50

 tggttgctgt aaggggtcct ccctgcgcca cacggccgtc gccatggtga 100

 agctgagcaa agaggccaag cagagactac agcagctctt caaggggagc 150

 cagtttgcca ttcgctgggg ctttatccct cttgtgattt acctgggatt 200

 taagaggggt gcagatcccg gaatgcctga accaactgtt ttgagcctac 250

 tttggggata aaggattatt tggtcttctg gatttggagg caatcagcgg 300

 acagcatgga agatgtgtgc tctggctcgg ataagagatg ggacatcatt 350

 cagtcactag ttggatggca caaggctctt cacagacgca tctgtagcag 400

 agtggaactt gtactaactt atgatagaat gtatcagaat aaatgttttt 450

 aacagtgtaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 487

<210> 5865
<211> 55
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 22
<223> Unknown amino acid

<400> 5865
 Met Val Lys Leu Ser Lys Glu Ala Lys Gln Arg Leu Gln Gln Leu
   1               5                  10                  15

 Phe Lys Gly Ser Gln Phe Ala Ile Arg Trp Gly Phe Ile Pro Leu
                  20                  25                  30

 Val Ile Tyr Leu Gly Phe Lys Arg Gly Ala Asp Pro Gly Met Pro
                  35                  40                  45

 Glu Pro Thr Val Leu Ser Leu Leu Trp Gly
                  50                  55

<210> 5866
<211> 1926
<212> DNA
<213> Homo sapien

<400> 5866
 gctgctcccg ctcgcgtcgg tggcgttttt cctgcagcgc gtgcgtgctg 50

 cgctactgag cagcgccatg gaggactctg aagcactggg cttcgaacac 100

 atgggcctcg atccccggct ccttcaggct gtcaccgatc tgggctggtc 150

 gcgacctacg ctgatccagg agaaggccat cccactggcc ctagaaggga 200

 aggacctcct ggctcgggcc cgcacgggct ccgggaagac ggccgcttat 250

 gctattccga tgctgcagct gttgctccat aggaaggcga caggtccggt 300

 ggtagaacag gcagtgagag gccttgttct tgttcctacc aaggagctgg 350

 cacggcaagc acagtccatg attcagcagc tggctaccta ctgtgctcgg 400

 gatgtccgag tggccaatgt ctcagctgct gaagactcag tctctcagag 450

 agctgtgctg atggagaagc cagatgtggt agtagggacc ccatctcgca 500

 tattaagcca cttgcagcaa gacagcctga aacttcgtga ctccctggag 550

 cttttggtgg tggatgaagc tgaccttctt ttttcctttg gctttgaaga 600

 agagctcaag agtctcctct gtcacttgcc ccggatttac caggcttttc 650

 tcatgtcagc tacttttaac gaggacgtac aagcactcaa ggagctgata 700

 ttacataacc cggttaccct taagttacag gagtcccagc tgcctgggcc 750

 agaccagtta cagcagtttc aggtggtctg tgagactgag gaagacaaat 800

 tcctcctgct gtatgccctg ctcaagctgt cattgattcg gggcaagtct 850

 ctgctctttg tcaacactct agaacggagt taccggctac gcctgttctt 900

 ggaacagttc agcatcccca cctgtgtgct caatggagag cttccactgc 950

 gctccaggtg ccacatcatc tcacagttca accaaggctt ctacgactgt 1000

 gtcatagcaa ctgatgctga agtcctgggg gccccagtca agggcaagcg 1050

 tcggggccga gggcccaaag gggacaaggc ctctgatccg gaagcaggtg 1100

 tggcccgggg catagacttc caccatgtgt ctgctgtgct caactttgat 1150

 cttcccccaa cccctgaggc ctacatccat cgagctggca ggacagcacg 1200

 cgctaacaac ccaggcatag tcttaacctt tgtgcttccc acggagcagt 1250

 tccacttagg caagattgag gagcttctca gtggagagaa caggggcccc 1300

 attctgctcc cctaccagtt ccggatggag gagatcgagg gcttccgcta 1350

 tcgctgcagg gatgccatgc gctcagtgac taagcaggcc attcgggagg 1400

 caagattgaa ggagatcaag gaagagcttc tgcattctga gaagcttaag 1450

 acatactttg aagacaaccc tagggacctc cagctgctgc ggcatgacct 1500

 acctttgcac cccgcagtgg tgaagcccca cctgggccat gttcctgact 1550

 acctggttcc tcctgctctc cgtggcctgg tacgccctca caagaagcgg 1600

 aagaagctgt cttcctcttg taggaaggcc aagagagcaa agtcccagaa 1650

 cccactgcgc agcttcaagc acaaaggaaa gaaattcaga cccacagcca 1700

 agccctcctg aggttgttgg gcctctctgg agctgagcac attgtggagc 1750

 acaggcttac acccttcgtg gacaggcgag gctctggtgc ttactgcaca 1800

 gcctgaacag acagttctgg ggccggcagt gctgggccct ttagctcctt 1850

 ggcacttcca agctggcatc ttgccccttg acaacagaat aaaaatttta 1900

 gctgccccaa aaaaaaaaaa aaaaaa 1926

<210> 5867
<211> 547
<212> PRT
<213> Homo sapien

<400> 5867
 Met Glu Asp Ser Glu Ala Leu Gly Phe Glu His Met Gly Leu Asp
   1               5                  10                  15

 Pro Arg Leu Leu Gln Ala Val Thr Asp Leu Gly Trp Ser Arg Pro
                  20                  25                  30

 Thr Leu Ile Gln Glu Lys Ala Ile Pro Leu Ala Leu Glu Gly Lys
                  35                  40                  45

 Asp Leu Leu Ala Arg Ala Arg Thr Gly Ser Gly Lys Thr Ala Ala
                  50                  55                  60

 Tyr Ala Ile Pro Met Leu Gln Leu Leu Leu His Arg Lys Ala Thr
                  65                  70                  75

 Gly Pro Val Val Glu Gln Ala Val Arg Gly Leu Val Leu Val Pro
                  80                  85                  90

 Thr Lys Glu Leu Ala Arg Gln Ala Gln Ser Met Ile Gln Gln Leu
                  95                 100                 105

 Ala Thr Tyr Cys Ala Arg Asp Val Arg Val Ala Asn Val Ser Ala
                 110                 115                 120

 Ala Glu Asp Ser Val Ser Gln Arg Ala Val Leu Met Glu Lys Pro
                 125                 130                 135

 Asp Val Val Val Gly Thr Pro Ser Arg Ile Leu Ser His Leu Gln
                 140                 145                 150

 Gln Asp Ser Leu Lys Leu Arg Asp Ser Leu Glu Leu Leu Val Val
                 155                 160                 165

 Asp Glu Ala Asp Leu Leu Phe Ser Phe Gly Phe Glu Glu Glu Leu
                 170                 175                 180

 Lys Ser Leu Leu Cys His Leu Pro Arg Ile Tyr Gln Ala Phe Leu
                 185                 190                 195

 Met Ser Ala Thr Phe Asn Glu Asp Val Gln Ala Leu Lys Glu Leu
                 200                 205                 210

 Ile Leu His Asn Pro Val Thr Leu Lys Leu Gln Glu Ser Gln Leu
                 215                 220                 225

 Pro Gly Pro Asp Gln Leu Gln Gln Phe Gln Val Val Cys Glu Thr
                 230                 235                 240

 Glu Glu Asp Lys Phe Leu Leu Leu Tyr Ala Leu Leu Lys Leu Ser
                 245                 250                 255

 Leu Ile Arg Gly Lys Ser Leu Leu Phe Val Asn Thr Leu Glu Arg
                 260                 265                 270

 Ser Tyr Arg Leu Arg Leu Phe Leu Glu Gln Phe Ser Ile Pro Thr
                 275                 280                 285

 Cys Val Leu Asn Gly Glu Leu Pro Leu Arg Ser Arg Cys His Ile
                 290                 295                 300

 Ile Ser Gln Phe Asn Gln Gly Phe Tyr Asp Cys Val Ile Ala Thr
                 305                 310                 315

 Asp Ala Glu Val Leu Gly Ala Pro Val Lys Gly Lys Arg Arg Gly
                 320                 325                 330

 Arg Gly Pro Lys Gly Asp Lys Ala Ser Asp Pro Glu Ala Gly Val
                 335                 340                 345

 Ala Arg Gly Ile Asp Phe His His Val Ser Ala Val Leu Asn Phe
                 350                 355                 360

 Asp Leu Pro Pro Thr Pro Glu Ala Tyr Ile His Arg Ala Gly Arg
                 365                 370                 375

 Thr Ala Arg Ala Asn Asn Pro Gly Ile Val Leu Thr Phe Val Leu
                 380                 385                 390

 Pro Thr Glu Gln Phe His Leu Gly Lys Ile Glu Glu Leu Leu Ser
                 395                 400                 405

 Gly Glu Asn Arg Gly Pro Ile Leu Leu Pro Tyr Gln Phe Arg Met
                 410                 415                 420

 Glu Glu Ile Glu Gly Phe Arg Tyr Arg Cys Arg Asp Ala Met Arg
                 425                 430                 435

 Ser Val Thr Lys Gln Ala Ile Arg Glu Ala Arg Leu Lys Glu Ile
                 440                 445                 450

 Lys Glu Glu Leu Leu His Ser Glu Lys Leu Lys Thr Tyr Phe Glu
                 455                 460                 465

 Asp Asn Pro Arg Asp Leu Gln Leu Leu Arg His Asp Leu Pro Leu
                 470                 475                 480

 His Pro Ala Val Val Lys Pro His Leu Gly His Val Pro Asp Tyr
                 485                 490                 495

 Leu Val Pro Pro Ala Leu Arg Gly Leu Val Arg Pro His Lys Lys
                 500                 505                 510

 Arg Lys Lys Leu Ser Ser Ser Cys Arg Lys Ala Lys Arg Ala Lys
                 515                 520                 525

 Ser Gln Asn Pro Leu Arg Ser Phe Lys His Lys Gly Lys Lys Phe
                 530                 535                 540

 Arg Pro Thr Ala Lys Pro Ser
                 545

<210> 5868
<211> 1199
<212> DNA
<213> Homo sapien

<400> 5868
 actcccaacg agcgcccaag aagaaaatgg ccataagtgg agtccctgtg 50

 ctaggatttt tcatcatagc tgtgctgatg agcgctcagg aatcatgggc 100

 tatcaaagaa gaacatgtga tcatccaggc cgagttctat ctgaatcctg 150

 accaatcagg cgagtttatg tttgactttg atggtgatga gattttccat 200

 gtggatatgg caaagaagga gacggtctgg cggcttgaag aatttggacg 250

 atttgccagc tttgaggctc aaggtgcatt ggccaacata gctgtggaca 300

 aagccaacct ggaaatcatg acaaagcgct ccaactatac tccgatcacc 350

 aatgtacctc cagaggtaac tgtgctcacg aacagccctg tggaactgag 400

 agagcccaac gtcctcatct gtttcatcga caagttcacc ccaccagtgg 450

 tcaatgtcac gtggcttcga aatggaaaac ctgtcaccac aggagtgtca 500

 gagacagtct tcctgcccag ggaagaccac cttttccgca agttccacta 550

 tctccccttc ctgccctcaa ctgaggacgt ttacgactgc agggtggagc 600

 actggggctt ggatgagcct cttctcaagc actgggagtt tgatgctcca 650

 agccctctcc cagagactac agagaacgtg gtgtgtgccc tgggcctgac 700

 tgtgggtctg gtgggcatca ttattgggac catcttcatc atcaagggag 750

 tgcgcaaaag caatgcagca gaacgcaggg ggcctctgta aggcacatgg 800

 aggtgatgat gtttcttaga gagaagatca ctgaagaaac ttctgcttta 850

 atgactttac aaagctggca atattacaat ccttgacctc agtgaaagca 900

 gtcatcttca gcgttttcca gccctatagc caccccaagt gtggttatgc 950

 ctcctcgatt gctccgtact ctaacatcta gctggctttc cctgtctatt 1000

 gccttttcct gtatctattt tcctctattt cctatcattt tattatcacc 1050

 atgcaatgcc tctggaataa aacatacagg agtctgtctc tgctatggaa 1100

 tgccccatgg ggctctcttg tgtacttatt gtttaaggtt tcctcaaact 1150

 gtgatttttc tgaacacaat aaactatttt gatgatcttg ggtggaaaa 1199

<210> 5869
<211> 254
<212> PRT
<213> Homo sapien

<400> 5869
 Met Ala Ile Ser Gly Val Pro Val Leu Gly Phe Phe Ile Ile Ala
   1               5                  10                  15

 Val Leu Met Ser Ala Gln Glu Ser Trp Ala Ile Lys Glu Glu His
                  20                  25                  30

 Val Ile Ile Gln Ala Glu Phe Tyr Leu Asn Pro Asp Gln Ser Gly
                  35                  40                  45

 Glu Phe Met Phe Asp Phe Asp Gly Asp Glu Ile Phe His Val Asp
                  50                  55                  60

 Met Ala Lys Lys Glu Thr Val Trp Arg Leu Glu Glu Phe Gly Arg
                  65                  70                  75

 Phe Ala Ser Phe Glu Ala Gln Gly Ala Leu Ala Asn Ile Ala Val
                  80                  85                  90

 Asp Lys Ala Asn Leu Glu Ile Met Thr Lys Arg Ser Asn Tyr Thr
                  95                 100                 105

 Pro Ile Thr Asn Val Pro Pro Glu Val Thr Val Leu Thr Asn Ser
                 110                 115                 120

 Pro Val Glu Leu Arg Glu Pro Asn Val Leu Ile Cys Phe Ile Asp
                 125                 130                 135

 Lys Phe Thr Pro Pro Val Val Asn Val Thr Trp Leu Arg Asn Gly
                 140                 145                 150

 Lys Pro Val Thr Thr Gly Val Ser Glu Thr Val Phe Leu Pro Arg
                 155                 160                 165

 Glu Asp His Leu Phe Arg Lys Phe His Tyr Leu Pro Phe Leu Pro
                 170                 175                 180

 Ser Thr Glu Asp Val Tyr Asp Cys Arg Val Glu His Trp Gly Leu
                 185                 190                 195

 Asp Glu Pro Leu Leu Lys His Trp Glu Phe Asp Ala Pro Ser Pro
                 200                 205                 210

 Leu Pro Glu Thr Thr Glu Asn Val Val Cys Ala Leu Gly Leu Thr
                 215                 220                 225

 Val Gly Leu Val Gly Ile Ile Ile Gly Thr Ile Phe Ile Ile Lys
                 230                 235                 240

 Gly Val Arg Lys Ser Asn Ala Ala Glu Arg Arg Gly Pro Leu
                 245                 250

<210> 5870
<211> 2820
<212> DNA
<213> Homo sapien

<400> 5870
 gggattttta aaaaatcaaa atacaaatcc aactttttga gttttcgttg 50

 tcattgctct tatctttcct gagtcacttc ccattttcca aactcagcaa 100

 ccccagtttg cgagtctggt ttcatgaacc tttgtaaggt gtttggtgcg 150

 gtcacrgtgt atacttgccg tgtagtattt gactcagcgc gatctgcctt 200

 gagtcatttt accgcggcca tttactactg ccgttgagcc ctgtccacgc 250

 cttgggagtg ttgatatgtt gagagttttc tgtctggctg rggagggatc 300

 atttagtttt tgcggacgta tgttgcactg aggatttagg gagagagcaa 350

 gatttctgtt gaggaggttc agaagtataa ggaatcggga gagtagatag 400

 gagtgaagca tttggcagcg taaagaagct tggcttagct ttaatggatt 450

 agggagagat tgctatctag cattattaca tgttattgtt ctctttgcta 500

 ttttatacac ctagaacaac ctttccctcg gggttaacaa acatcttcaa 550

 ctctgttttc tgtatggctc ctgactctta cctttgtttt aggaggcttc 600

 cctcttcaga ggaaactggg agaagccaat ttccactgct tctttttcct 650

 gtgccttttt aacactcaaa cccagaacac ttaatcctct gcagctcgtg 700

 caaaaattca gtctgtaatt taaaatgtgt gcacggtaca ctgctgacca 750

 tgggcatgtc tattgtttgt atctgtaatg tgtatgtcca tttcagtgtt 800

 gtctgtttta gtatgcaggt gatagactag agaacaagac ctctgtctcc 850

 gtagcatcct ggagcagtct gaatgccaga atggataacc gttttgctac 900

 agcatttgta attgcttgtg tgcttagcct catttccacc atctacatgg 950

 cagcctccat tggcacagac ttctggtatg aatatcgaag tccagttcaa 1000

 gaaaattcca gtgatttgaa taaaagcatc tgggatgaat tcattagtga 1050

 tgaggcagat gaaaagactt ataatgatgc actttttcga tacaatggca 1100

 cagtgggatt gtggagacgg tgtatcacca tacccaaaaa catgcattgg 1150

 tatagcccac cagaaaggac agagtcattt gatgtggtca caaaatgtgt 1200

 gagtttcaca ctaactgagc agttcatgga gaaatttgtt gatcccggaa 1250

 accacaatag cgggattgat ctccttagga cctatctttg gcgttgccag 1300

 ttccttttac cttttgtgag tttaggtttg atgtgctttg gggctttgat 1350

 cggactttgt gcttgcattt gccgaagctt atatcccacc attgccacgg 1400

 gcattctcca tctccttgca ggtctgtgta cactgggctc agtaagttgt 1450

 tatgttgctg gaattgaact actccaccag aaactagagc tccctgacaa 1500

 tgtatccggt gaatttggat ggtccttctg cctggcttgt gtctctgctc 1550

 ccttacagtt catggcttct gctctcttca tctgggctgc tcacaccaac 1600

 cggaaagagt acaccttaat gaaggcatat cgtgtggcat gagcaagaaa 1650

 ctgcctgctt tacaattgcc atttttattt ttttaaaata atactgatat 1700

 tttccccacc tctcaattgt ttttaatttt tatttgtgga tataccattt 1750

 tattatgaaa atctatttta tttatacaca ttcaccacta aatacacact 1800

 taataccact aaaatttatg tggtttactt taagcgatgc catctttcaa 1850

 ataaactaat ctaggtctag acagaaagaa atggatagag acttgacaca 1900

 aatttatgaa agaaaattgg gagtaggaat gtgaccgaaa acaagttgtg 1950

 ctaatgtctg ttagactttt cagtaaaact aaagtaactg tatctgttca 2000

 actaaaaact ctatattagt ttctttggga aacctctcat cgtcaaaact 2050

 ttatgttcac tttgctgttg tagatagcca gtcaaccagc agtattagtg 2100

 ctgttttcaa agatttaagc tctataaaat tgggaaatta tctaagatca 2150

 ttttccctaa gcattgacac atagcttcat ctgaggtgag atatggcagc 2200

 tgtttgtatc tgcactgtgt ctgtctacaa aaagtgaaaa atacagtgtt 2250

 tacttgaaat tttaactttg taactgcaag aattccagtt cagccgggcg 2300

 aggattagta ttatttttaa ctctccgtaa gattttcagt accaccaaat 2350

 tgttttggat tttttttctt tcctcttcac ataccagggt tattaaaagt 2400

 gtgctttctt tttacattat attacagtta caaggtaaaa ttcctcaact 2450

 gctatttatt tattccagcc cagtactata aagaacgttt caccataatg 2500

 accctccaga gctgggaaac ctaccacaag atctaaagtt ctggctgtcc 2550

 attaacctcc aactatggtc tttatttctt gtggtaatat gatgtgcctt 2600

 tccttgccta aatcccttcc tggtgtgtat caacattatt taatgtcttc 2650

 taattcagtc atttttttat aagtatgtct ataaacattg aactttaaaa 2700

 aacttattta tttattccac tactgtagca attgacagat taaaaaaatg 2750

 taacttcata atttcttacc ataacctcaa tgtctttttt aaaaaataaa 2800

 attaaaaatg aaaagagaaa 2820

<210> 5871
<211> 253
<212> PRT
<213> Homo sapien

<400> 5871
 Met Asp Asn Arg Phe Ala Thr Ala Phe Val Ile Ala Cys Val Leu
   1               5                  10                  15

 Ser Leu Ile Ser Thr Ile Tyr Met Ala Ala Ser Ile Gly Thr Asp
                  20                  25                  30

 Phe Trp Tyr Glu Tyr Arg Ser Pro Val Gln Glu Asn Ser Ser Asp
                  35                  40                  45

 Leu Asn Lys Ser Ile Trp Asp Glu Phe Ile Ser Asp Glu Ala Asp
                  50                  55                  60

 Glu Lys Thr Tyr Asn Asp Ala Leu Phe Arg Tyr Asn Gly Thr Val
                  65                  70                  75

 Gly Leu Trp Arg Arg Cys Ile Thr Ile Pro Lys Asn Met His Trp
                  80                  85                  90

 Tyr Ser Pro Pro Glu Arg Thr Glu Ser Phe Asp Val Val Thr Lys
                  95                 100                 105

 Cys Val Ser Phe Thr Leu Thr Glu Gln Phe Met Glu Lys Phe Val
                 110                 115                 120

 Asp Pro Gly Asn His Asn Ser Gly Ile Asp Leu Leu Arg Thr Tyr
                 125                 130                 135

 Leu Trp Arg Cys Gln Phe Leu Leu Pro Phe Val Ser Leu Gly Leu
                 140                 145                 150

 Met Cys Phe Gly Ala Leu Ile Gly Leu Cys Ala Cys Ile Cys Arg
                 155                 160                 165

 Ser Leu Tyr Pro Thr Ile Ala Thr Gly Ile Leu His Leu Leu Ala
                 170                 175                 180

 Gly Leu Cys Thr Leu Gly Ser Val Ser Cys Tyr Val Ala Gly Ile
                 185                 190                 195

 Glu Leu Leu His Gln Lys Leu Glu Leu Pro Asp Asn Val Ser Gly
                 200                 205                 210

 Glu Phe Gly Trp Ser Phe Cys Leu Ala Cys Val Ser Ala Pro Leu
                 215                 220                 225

 Gln Phe Met Ala Ser Ala Leu Phe Ile Trp Ala Ala His Thr Asn
                 230                 235                 240

 Arg Lys Glu Tyr Thr Leu Met Lys Ala Tyr Arg Val Ala
                 245                 250

<210> 5872
<211> 1048
<212> DNA
<213> Homo sapien

<400> 5872
 ccccgcacga aaccgagttc tggagaacgc catcagctcg ctgcttaaaa 50

 ttaaaccaca ggttccatta tgggtcgact tgatgggaaa gtcatcatcc 100

 tgacggccgc tgctcagggg attggccaag cagctgcctt agcttttgca 150

 agagaaggtg ccaaagtcat agccacagac attaatgagt ccaaacttca 200

 ggaactggaa aagtacccgg gtattcaaac tcgtgtcctt gatgtcacaa 250

 agaagaaaca aattgatcag tttgccaatg aagttgagag acttgatgtt 300

 ctctttaatg ttgctggttt tgtccatcat ggaactgtcc tggattgtga 350

 ggagaaagac tgggacttct cgatgaatct caatgtgcgc agcatgtacc 400

 tgatgatcaa ggcattcctt cctaaaatgc ttgctcagaa atctggcaat 450

 attatcaaca tgtcttctgt ggcttccagc gtcaaaggag ttgtgaacag 500

 atgtgtgtac agcacaacca aggcagccgt gattggcctc acaaaatctg 550

 tggctgcaga tttcatccag cagggcatca ggtgcaactg tgtgtgccca 600

 ggaacagttg atacgccatc tctacaagaa agaatacaag ccagaggaaa 650

 tcctgaagag gcacggaatg atttcctgaa gagacaaaag acgggaagat 700

 tcgcaactgc agaagaaata gccatgctct gcgtgtattt ggcttctgat 750

 gaatctgctt atgtaactgg taaccctgtc atcattgatg gaggctggag 800

 cttgtgattt taggatctcc atggtgggaa ggaaggcagg cccttcctat 850

 ccacagtgaa cctggttacg aagaaaactc accaatcatc tccttcctgt 900

 taatcacatg ttaatgaaaa taagctcttt ttaatgatgt cactgtttgc 950

 aagagtctga ttctttaagt atattaatct ctttgtaatc tcttctgaaa 1000

 tcattgtaaa gaaataaaaa tattgaactc ataaaaaaaa aaaaaaaa 1048

<210> 5873
<211> 245
<212> PRT
<213> Homo sapien

<400> 5873
 Met Gly Arg Leu Asp Gly Lys Val Ile Ile Leu Thr Ala Ala Ala
   1               5                  10                  15

 Gln Gly Ile Gly Gln Ala Ala Ala Leu Ala Phe Ala Arg Glu Gly
                  20                  25                  30

 Ala Lys Val Ile Ala Thr Asp Ile Asn Glu Ser Lys Leu Gln Glu
                  35                  40                  45

 Leu Glu Lys Tyr Pro Gly Ile Gln Thr Arg Val Leu Asp Val Thr
                  50                  55                  60

 Lys Lys Lys Gln Ile Asp Gln Phe Ala Asn Glu Val Glu Arg Leu
                  65                  70                  75

 Asp Val Leu Phe Asn Val Ala Gly Phe Val His His Gly Thr Val
                  80                  85                  90

 Leu Asp Cys Glu Glu Lys Asp Trp Asp Phe Ser Met Asn Leu Asn
                  95                 100                 105

 Val Arg Ser Met Tyr Leu Met Ile Lys Ala Phe Leu Pro Lys Met
                 110                 115                 120

 Leu Ala Gln Lys Ser Gly Asn Ile Ile Asn Met Ser Ser Val Ala
                 125                 130                 135

 Ser Ser Val Lys Gly Val Val Asn Arg Cys Val Tyr Ser Thr Thr
                 140                 145                 150

 Lys Ala Ala Val Ile Gly Leu Thr Lys Ser Val Ala Ala Asp Phe
                 155                 160                 165

 Ile Gln Gln Gly Ile Arg Cys Asn Cys Val Cys Pro Gly Thr Val
                 170                 175                 180

 Asp Thr Pro Ser Leu Gln Glu Arg Ile Gln Ala Arg Gly Asn Pro
                 185                 190                 195

 Glu Glu Ala Arg Asn Asp Phe Leu Lys Arg Gln Lys Thr Gly Arg
                 200                 205                 210

 Phe Ala Thr Ala Glu Glu Ile Ala Met Leu Cys Val Tyr Leu Ala
                 215                 220                 225

 Ser Asp Glu Ser Ala Tyr Val Thr Gly Asn Pro Val Ile Ile Asp
                 230                 235                 240

 Gly Gly Trp Ser Leu
                 245

<210> 5874
<211> 3003
<212> DNA
<213> Homo sapien

<400> 5874
 ctagttctag atccggcgag tagctggcgg tcccgggtgc tgctggttag 50

 tgtgctctga gggagggtcc gagccagccg ctgttttgcc ggaggagccc 100

 ctcaggccgt agtaagcatt aataatgtct ttcatctttg agtggatcta 150

 caatggcttc agcagtgtgc tccagttcct aggactgtac aagaaatctg 200

 gaaaacttgt attcttaggt ttggataatg caggcaaaac cactcttctt 250

 cacatgctca aagatgacag attgggccaa catgttccaa cactacatcc 300

 gacatcagaa gagctaacaa ttgctggaat gacctttaca acttttgatc 350

 ttggtgggca cgagcaagca cgtcgcgttt ggaaaaatta tctcccagca 400

 attaatggga ttgtctttct ggtggactgt gcagatcatt ctcgcctcgt 450

 ggaatccaaa gttgagctta atgctttaat gactgatgaa acaatatcca 500

 atgtgccaat ccttatcttg ggtaacaaaa ttgacagaac agatgcaatc 550

 agtgaagaaa aactccgtga gatatttggg ctttatggac agaccacagg 600

 aaaggggaat gtgaccctga aggagctgaa tgctcgcccc atggaagtgt 650

 tcatgtgcag tgtgctcaag aggcaaggtt acggcgaggg tttccgctgg 700

 ctctcccagt atattgactg atgtttggac ggtgaaaata aaagagtttt 750

 acttctctgg actgatccta ttcacagctt cctcatgaac ttttctaata 800

 gaacaaggaa agctctccaa ccatgtctgg cgttgagaag ccaagagtct 850

 ctgtcaactc tctcattgcc cagtggtgac atgtgctctt ctccacactg 900

 ttgggaggta atgctgcccc acgtgctggt gcaggtcagt atcctgggac 950

 ttggaagctg gcaggatttg ccgggtaaag ctgtatgcca tcatggggca 1000

 cctgaaaaga aaaacacgtc tcaccactgt ggttgattca aaagaaagtg 1050

 attctatttt ttaaagaaag cgttgttaat gtaattggta tccctcctaa 1100

 ctttttgagt tcacaattta cttggtccag agttttctat tctttttttt 1150

 ttttaaacta atgaatgaca tttagatact tcataaaatt atgaacagat 1200

 atggaggcca gagctcattt gggtaaactt actcctgctg agttagcagg 1250

 ttggtgagag aagctcccct gagctcacct gtctctctga ctgccttgga 1300

 gtaggtggca taaccttgtg cacagagaac tagaaaaggg gcagaacccc 1350

 ggccttgcag ttgtggcagg tttccactgt ggtaagctag gttcattcct 1400

 catcaaggaa tgtgtagcag attgttcact gtggaggagt taattataga 1450

 atgggttatt gttgttattc ttactcatga agttacagat tttagccagt 1500

 ctttgctttt atacttttgt gaaatttaat ttctctctat agcaccttcc 1550

 tttttcgttt tcagttatca aaagtgactt tgacctcata aaagagttga 1600

 gaacatctct cgtgtcacat actgcaggtg catcagttac ttttgcacag 1650

 attctggggg acatttttct gaataggaag acaggacaaa gttaacagct 1700

 taagggctct taattctgtg agttgaggac ttaaaagtat tgtagcattt 1750

 gtttggatcc atgaaaaatg tattcagtgg gctttaaaat ttccatttgc 1800

 agaatttggt ctctcaggct gtttgggagc tctttttttt acattttttc 1850

 tcctttgaca cctattttat tggtgtttaa agtaaaggtt aacatctgta 1900

 gcttttccag gttttttttt tttttttttt gatatgaaat tgtctttctc 1950

 cattgcagaa ataagctagg gaaacactaa cccaaaaact ttctgtagag 2000

 ctgttccttt ggaggcagca tcacttattg gcagtaaaga ctcagtataa 2050

 aagcaccagc atccctactt gggtgatggg gattaatttt atagcattcc 2100

 attttcctag tgccacatgt gaaattggat tttgatgatc ttaatctata 2150

 ttctaccctt ataataaaag atcaaaagat atatctccta tgaacagatt 2200

 ggagatagga gatgaaaagt tgggaggatg tctttattct aatgtgaggg 2250

 tagggaaaat gtggataaca ttactggggt gaaggaggca ttgttcttta 2300

 gttggagttc tcatttttat tctccagtac tgacttgtgg ggaaagcata 2350

 ctttttcact gccaggtact gaatgcagag gctcagtgaa gtatatatgt 2400

 gggaagtgca tgcatttcgt ttattagcaa acatagctgg attaagacaa 2450

 agttgttggt ttggaaaggg gttaaagcct taagtgaaca aatctagcta 2500

 acagtgaatg aactaggtaa tataacttgc atatttttaa tttcctttgg 2550

 ttaaaggtcc cccatacttc tctgttcgga gacatgagaa gtatgattac 2600

 ttcagtgtta gttttcttaa tttttttttt cccctatttg tcccttgtca 2650

 ctttgttgca agctagaaat ctgtgggtta tacatagggc agctctttgt 2700

 gaaagtggtt tattccactg gagaaagggg attgaaaatc agttagaacc 2750

 aatgtatttc ttgccccacg gaacactatt cctataagat agctgaaaga 2800

 agctgctgtg aggagctcag ctccaaacac aggatcagca ccttgtatag 2850

 gaattcccat gaattatgac ttctcattct gttttatcag agtgcatata 2900

 tgtcctactt caggaaaagt aaaacagtca tttacgaaag aaagtcaatc 2950

 tgtatcctaa gcattttaat aaaaagttaa aacaaaaaaa aaaaaaaaaa 3000

 aaa 3003

<210> 5875
<211> 198
<212> PRT
<213> Homo sapien

<400> 5875
 Met Ser Phe Ile Phe Glu Trp Ile Tyr Asn Gly Phe Ser Ser Val
   1               5                  10                  15

 Leu Gln Phe Leu Gly Leu Tyr Lys Lys Ser Gly Lys Leu Val Phe
                  20                  25                  30

 Leu Gly Leu Asp Asn Ala Gly Lys Thr Thr Leu Leu His Met Leu
                  35                  40                  45

 Lys Asp Asp Arg Leu Gly Gln His Val Pro Thr Leu His Pro Thr
                  50                  55                  60

 Ser Glu Glu Leu Thr Ile Ala Gly Met Thr Phe Thr Thr Phe Asp
                  65                  70                  75

 Leu Gly Gly His Glu Gln Ala Arg Arg Val Trp Lys Asn Tyr Leu
                  80                  85                  90

 Pro Ala Ile Asn Gly Ile Val Phe Leu Val Asp Cys Ala Asp His
                  95                 100                 105

 Ser Arg Leu Val Glu Ser Lys Val Glu Leu Asn Ala Leu Met Thr
                 110                 115                 120

 Asp Glu Thr Ile Ser Asn Val Pro Ile Leu Ile Leu Gly Asn Lys
                 125                 130                 135

 Ile Asp Arg Thr Asp Ala Ile Ser Glu Glu Lys Leu Arg Glu Ile
                 140                 145                 150

 Phe Gly Leu Tyr Gly Gln Thr Thr Gly Lys Gly Asn Val Thr Leu
                 155                 160                 165

 Lys Glu Leu Asn Ala Arg Pro Met Glu Val Phe Met Cys Ser Val
                 170                 175                 180

 Leu Lys Arg Gln Gly Tyr Gly Glu Gly Phe Arg Trp Leu Ser Gln
                 185                 190                 195

 Tyr Ile Asp


<210> 5876
<211> 1578
<212> DNA
<213> Homo sapien

<400> 5876
 aggaggcctc gtggaggaca cagcagcatg ggacagtcag ggaggtcccg 50

 gcaccagaag cgcgcccgcg cccaggcgca gctccgcaac ctcgaggcct 100

 atgccgcgaa cccgcactcg ttcgtgttca cgcgaggctg cacgggtcgc 150

 aacatccggc agctcagcct ggacgtgcgg cgggtcatgg agccgctcac 200

 tgccagccgt ctgcaggttc gtaagaagaa ctcgctgaag gactgcgtgg 250

 cagtggctgg gcccctcggg gtcacacact ttctgatcct gagcaaaaca 300

 gagaccaatg tctactttaa gctgatgcgc ctcccaggag gccccacctt 350

 gaccttccag gtgaagaagt actcgctggt gcgtgatgtg gtctcctcac 400

 tgcgccggca ccgcatgcac gagcagcagt ttgcccaccc acccctcctg 450

 gtactcaaca gctttggccc ccatggtatg catgtgaagc tcatggccac 500

 catgttccag aacctgttcc cctccatcaa cgtgcacaag gtgaacctga 550

 acaccatcaa gcgctgcctc ctcatcgact acaaccccga ctcccaggag 600

 ctggacttcc gccactatag catcaaagtt gttcctgtgg gcgcgagtcg 650

 cgggatgaag aagctgctcc aggagaagtt ccccaacatg agccgcctgc 700

 aggacatcag cgagctgctg gccacgggcg cggggctgtc ggagagcgag 750

 gcagagcctg acggcgacca caacatcaca gagctgcctc aggctgtcgc 800

 tggccgtggc aacatgcggg cccagcagag tgcagtgcgg ctcaccgaga 850

 tcggcccgcg gatgacactg cagctcatca aggtccagga gggcgtcggg 900

 gagggcaaag tgatgttcca cagttttgtg agcaagacgg aggaggagct 950

 gcaggccatc ctggaagcca aggagaagaa gctgcggctg aaggcgcaga 1000

 ggcaggccca gcaggcccag aatgtgcagc gcaagcagga gcagcgggag 1050

 gcccacagaa agaagagcct ggagggcatg aagaaggcac gggtcggggg 1100

 tagtgatgaa gaggcctctg ggatcccttc aaggacggcg agcctggagt 1150

 tgggtgagga cgatgatgaa caggaagatg atgacatcga gtatttctgc 1200

 caggcggtgg gcgaggcgcc cagtgaggac ctgttccccg aggccaagca 1250

 gaaacggctt gccaagtctc cagggcggaa gcggaagcgg tgggaaatgg 1300

 atcgaggcag gggtcgcctt tgtgaccaga agtttcccaa gaccaaggac 1350

 aagtcccagg gagcccaggc caggcggggg cccagagggg cttcccggga 1400

 tggtgggcga ggccggggcc ggggccgccc agggaagaga gtggcctgag 1450

 cccaagccgc accggagcag cggctggatt gaacgcccca gattggggcc 1500

 cgagatgtgg ccctcggttt cctttcataa aggagttgtg tccccagccc 1550

 ttccactcca gtaaagaact gaattggc 1578

<210> 5877
<211> 473
<212> PRT
<213> Homo sapien

<400> 5877
 Met Gly Gln Ser Gly Arg Ser Arg His Gln Lys Arg Ala Arg Ala
   1               5                  10                  15

 Gln Ala Gln Leu Arg Asn Leu Glu Ala Tyr Ala Ala Asn Pro His
                  20                  25                  30

 Ser Phe Val Phe Thr Arg Gly Cys Thr Gly Arg Asn Ile Arg Gln
                  35                  40                  45

 Leu Ser Leu Asp Val Arg Arg Val Met Glu Pro Leu Thr Ala Ser
                  50                  55                  60

 Arg Leu Gln Val Arg Lys Lys Asn Ser Leu Lys Asp Cys Val Ala
                  65                  70                  75

 Val Ala Gly Pro Leu Gly Val Thr His Phe Leu Ile Leu Ser Lys
                  80                  85                  90

 Thr Glu Thr Asn Val Tyr Phe Lys Leu Met Arg Leu Pro Gly Gly
                  95                 100                 105

 Pro Thr Leu Thr Phe Gln Val Lys Lys Tyr Ser Leu Val Arg Asp
                 110                 115                 120

 Val Val Ser Ser Leu Arg Arg His Arg Met His Glu Gln Gln Phe
                 125                 130                 135

 Ala His Pro Pro Leu Leu Val Leu Asn Ser Phe Gly Pro His Gly
                 140                 145                 150

 Met His Val Lys Leu Met Ala Thr Met Phe Gln Asn Leu Phe Pro
                 155                 160                 165

 Ser Ile Asn Val His Lys Val Asn Leu Asn Thr Ile Lys Arg Cys
                 170                 175                 180

 Leu Leu Ile Asp Tyr Asn Pro Asp Ser Gln Glu Leu Asp Phe Arg
                 185                 190                 195

 His Tyr Ser Ile Lys Val Val Pro Val Gly Ala Ser Arg Gly Met
                 200                 205                 210

 Lys Lys Leu Leu Gln Glu Lys Phe Pro Asn Met Ser Arg Leu Gln
                 215                 220                 225

 Asp Ile Ser Glu Leu Leu Ala Thr Gly Ala Gly Leu Ser Glu Ser
                 230                 235                 240

 Glu Ala Glu Pro Asp Gly Asp His Asn Ile Thr Glu Leu Pro Gln
                 245                 250                 255

 Ala Val Ala Gly Arg Gly Asn Met Arg Ala Gln Gln Ser Ala Val
                 260                 265                 270

 Arg Leu Thr Glu Ile Gly Pro Arg Met Thr Leu Gln Leu Ile Lys
                 275                 280                 285

 Val Gln Glu Gly Val Gly Glu Gly Lys Val Met Phe His Ser Phe
                 290                 295                 300

 Val Ser Lys Thr Glu Glu Glu Leu Gln Ala Ile Leu Glu Ala Lys
                 305                 310                 315

 Glu Lys Lys Leu Arg Leu Lys Ala Gln Arg Gln Ala Gln Gln Ala
                 320                 325                 330

 Gln Asn Val Gln Arg Lys Gln Glu Gln Arg Glu Ala His Arg Lys
                 335                 340                 345

 Lys Ser Leu Glu Gly Met Lys Lys Ala Arg Val Gly Gly Ser Asp
                 350                 355                 360

 Glu Glu Ala Ser Gly Ile Pro Ser Arg Thr Ala Ser Leu Glu Leu
                 365                 370                 375

 Gly Glu Asp Asp Asp Glu Gln Glu Asp Asp Asp Ile Glu Tyr Phe
                 380                 385                 390

 Cys Gln Ala Val Gly Glu Ala Pro Ser Glu Asp Leu Phe Pro Glu
                 395                 400                 405

 Ala Lys Gln Lys Arg Leu Ala Lys Ser Pro Gly Arg Lys Arg Lys
                 410                 415                 420

 Arg Trp Glu Met Asp Arg Gly Arg Gly Arg Leu Cys Asp Gln Lys
                 425                 430                 435

 Phe Pro Lys Thr Lys Asp Lys Ser Gln Gly Ala Gln Ala Arg Arg
                 440                 445                 450

 Gly Pro Arg Gly Ala Ser Arg Asp Gly Gly Arg Gly Arg Gly Arg
                 455                 460                 465

 Gly Arg Pro Gly Lys Arg Val Ala
                 470

<210> 5878
<211> 2121
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1524
<223> Unknown base

<400> 5878
 atgggggacg agcggcccca ctactacggg aaacacggaa cgccacagaa 50

 gtatgatccc actttcaaag gacccattta caataggggc tgcacggata 100

 tcatatgctg tgtgttcctg ctcctggcca ttgtgggcta cgtggctgta 150

 ggcatcatag cctggactca tggagaccct cgaaaggtga tctaccccac 200

 tgatagccgg ggcgagttct gcgggcagaa gggcacaaaa aacgagaaca 250

 aaccctatct gttttatttc aacattgtga aatgtgccag ccccctggtt 300

 ctgctggaat tccaatgtcc cactccccag atctgcgtgg aaaaatgccc 350

 cgaccgctac ctcacgtacc tgaatgctcg cagctcccgg gactttgagt 400

 actataagca gttctgtgtt cctggcttca agaacaataa aggagtggct 450

 gaggtgcttc gagatggtga ctgccctgct gtcctcatcc ccagcaaacc 500

 cttggcccgg agatgcttcc ccgctatcca cgcctacaag ggtgtcctga 550

 tggtgggcaa tgagacgacc tatgaggatg ggcatggctc ccggaaaaac 600

 atcacagacc tggtggaggg cgccaagaaa gccaatggag tcctagaggc 650

 gcggcaactc gccatgcgca tatttgaaga ttacaccgtc tcttggtact 700

 ggattatcat aggcctggtc attgccatgg cgatgagcct cctgttcatc 750

 atcctgcttc gcttcctggc tggtattatg gtctgggtga tgatcatcat 800

 ggtgattctg gtgctgggct acggaatatt tcactgctac atggagtact 850

 cccgactgcg tggtgaggcc ggctctgatg tctctttggt ggacctcggc 900

 tttcagacgg atttccgggt gtacctgcac ttacggcaga cctggttggc 950

 ctttatgatc attctgagta tccttgaagt cattatcatc ttgctgctca 1000

 tctttctccg gaagagaatt ctcatcgcga ttgcactcat caaagaagcc 1050

 agcagggctg tgggatacgt catgtgctcc ttgctctacc cactggtcac 1100

 cttcttcttg ctgtgcctct gcatcgccta ctgggccagc actgctgtct 1150

 tcctgtccac ttccaacgaa gcggtctata agatctttga tgacagcccc 1200

 tgcccattta ctgcgaaaac ctgcaaccca gagaccttcc cctcctccaa 1250

 tgagtcccgc caatgcccca atgcccgttg ccagttcgcc ttctacggtg 1300

 gtgagtcggg ctaccaccgg gccctgctgg gcctgcagat cttcaatgcc 1350

 ttcatgttct tctggttggc caacttcgtg ctggcgctgg gccaggtcac 1400

 gctggccggg gcctttgcct cctattactg ggccctgcgc aagccggacg 1450

 acctgccggc cttcccgctc ttctctgcct ttggccgggc gctcaggtac 1500

 cacacaggct ccctggcctt tggngcgctc atcctggcca ttgtgcagat 1550

 catccgtgtg atactcgagt acctggatca gcggctgaaa ggtgcagaga 1600

 acaagtttgc caagtgcctc atgacctgtc tcaaatgctg cttctggtgc 1650

 ctggagaagt tcatcaaatt ccttaatagg aatgcctaca tcatgattgc 1700

 catctacggc accaatttct gcacctcggc caggaatgcc ttcttcctgc 1750

 tcatgagaaa catcatcaga gtggctgtcc tggataaagt tactgacttc 1800

 ctcttcctgt tgggcaaact tctgatcgtt ggtagtgtgg ggatcctggc 1850

 tttcttcttc ttcacccacc gtatcaggat cgtgcaggat acagcaccac 1900

 ccctcaatta ttactgggtt cctatactga cggtgatcgt tggctcctac 1950

 ttgattgcac acggtttctt cagcgtctat ggcatgtgtg tggacacgct 2000

 gttcctctgc ttcttggagg acctggagag gaatgacggc tcggccgaga 2050

 ggccttactt catgtcttcc accctcaaga aactcttgaa caagaccaac 2100

 aagaaggcag cggagtcctg a 2121

<210> 5879
<211> 706
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1524
<223> Unknown amino acid

<400> 5879
 Met Gly Asp Glu Arg Pro His Tyr Tyr Gly Lys His Gly Thr Pro
   1               5                  10                  15

 Gln Lys Tyr Asp Pro Thr Phe Lys Gly Pro Ile Tyr Asn Arg Gly
                  20                  25                  30

 Cys Thr Asp Ile Ile Cys Cys Val Phe Leu Leu Leu Ala Ile Val
                  35                  40                  45

 Gly Tyr Val Ala Val Gly Ile Ile Ala Trp Thr His Gly Asp Pro
                  50                  55                  60

 Arg Lys Val Ile Tyr Pro Thr Asp Ser Arg Gly Glu Phe Cys Gly
                  65                  70                  75

 Gln Lys Gly Thr Lys Asn Glu Asn Lys Pro Tyr Leu Phe Tyr Phe
                  80                  85                  90

 Asn Ile Val Lys Cys Ala Ser Pro Leu Val Leu Leu Glu Phe Gln
                  95                 100                 105

 Cys Pro Thr Pro Gln Ile Cys Val Glu Lys Cys Pro Asp Arg Tyr
                 110                 115                 120

 Leu Thr Tyr Leu Asn Ala Arg Ser Ser Arg Asp Phe Glu Tyr Tyr
                 125                 130                 135

 Lys Gln Phe Cys Val Pro Gly Phe Lys Asn Asn Lys Gly Val Ala
                 140                 145                 150

 Glu Val Leu Arg Asp Gly Asp Cys Pro Ala Val Leu Ile Pro Ser
                 155                 160                 165

 Lys Pro Leu Ala Arg Arg Cys Phe Pro Ala Ile His Ala Tyr Lys
                 170                 175                 180

 Gly Val Leu Met Val Gly Asn Glu Thr Thr Tyr Glu Asp Gly His
                 185                 190                 195

 Gly Ser Arg Lys Asn Ile Thr Asp Leu Val Glu Gly Ala Lys Lys
                 200                 205                 210

 Ala Asn Gly Val Leu Glu Ala Arg Gln Leu Ala Met Arg Ile Phe
                 215                 220                 225

 Glu Asp Tyr Thr Val Ser Trp Tyr Trp Ile Ile Ile Gly Leu Val
                 230                 235                 240

 Ile Ala Met Ala Met Ser Leu Leu Phe Ile Ile Leu Leu Arg Phe
                 245                 250                 255

 Leu Ala Gly Ile Met Val Trp Val Met Ile Ile Met Val Ile Leu
                 260                 265                 270

 Val Leu Gly Tyr Gly Ile Phe His Cys Tyr Met Glu Tyr Ser Arg
                 275                 280                 285

 Leu Arg Gly Glu Ala Gly Ser Asp Val Ser Leu Val Asp Leu Gly
                 290                 295                 300

 Phe Gln Thr Asp Phe Arg Val Tyr Leu His Leu Arg Gln Thr Trp
                 305                 310                 315

 Leu Ala Phe Met Ile Ile Leu Ser Ile Leu Glu Val Ile Ile Ile
                 320                 325                 330

 Leu Leu Leu Ile Phe Leu Arg Lys Arg Ile Leu Ile Ala Ile Ala
                 335                 340                 345

 Leu Ile Lys Glu Ala Ser Arg Ala Val Gly Tyr Val Met Cys Ser
                 350                 355                 360

 Leu Leu Tyr Pro Leu Val Thr Phe Phe Leu Leu Cys Leu Cys Ile
                 365                 370                 375

 Ala Tyr Trp Ala Ser Thr Ala Val Phe Leu Ser Thr Ser Asn Glu
                 380                 385                 390

 Ala Val Tyr Lys Ile Phe Asp Asp Ser Pro Cys Pro Phe Thr Ala
                 395                 400                 405

 Lys Thr Cys Asn Pro Glu Thr Phe Pro Ser Ser Asn Glu Ser Arg
                 410                 415                 420

 Gln Cys Pro Asn Ala Arg Cys Gln Phe Ala Phe Tyr Gly Gly Glu
                 425                 430                 435

 Ser Gly Tyr His Arg Ala Leu Leu Gly Leu Gln Ile Phe Asn Ala
                 440                 445                 450

 Phe Met Phe Phe Trp Leu Ala Asn Phe Val Leu Ala Leu Gly Gln
                 455                 460                 465

 Val Thr Leu Ala Gly Ala Phe Ala Ser Tyr Tyr Trp Ala Leu Arg
                 470                 475                 480

 Lys Pro Asp Asp Leu Pro Ala Phe Pro Leu Phe Ser Ala Phe Gly
                 485                 490                 495

 Arg Ala Leu Arg Tyr His Thr Gly Ser Leu Ala Phe Gly Ala Leu
                 500                 505                 510

 Ile Leu Ala Ile Val Gln Ile Ile Arg Val Ile Leu Glu Tyr Leu
                 515                 520                 525

 Asp Gln Arg Leu Lys Gly Ala Glu Asn Lys Phe Ala Lys Cys Leu
                 530                 535                 540

 Met Thr Cys Leu Lys Cys Cys Phe Trp Cys Leu Glu Lys Phe Ile
                 545                 550                 555

 Lys Phe Leu Asn Arg Asn Ala Tyr Ile Met Ile Ala Ile Tyr Gly
                 560                 565                 570

 Thr Asn Phe Cys Thr Ser Ala Arg Asn Ala Phe Phe Leu Leu Met
                 575                 580                 585

 Arg Asn Ile Ile Arg Val Ala Val Leu Asp Lys Val Thr Asp Phe
                 590                 595                 600

 Leu Phe Leu Leu Gly Lys Leu Leu Ile Val Gly Ser Val Gly Ile
                 605                 610                 615

 Leu Ala Phe Phe Phe Phe Thr His Arg Ile Arg Ile Val Gln Asp
                 620                 625                 630

 Thr Ala Pro Pro Leu Asn Tyr Tyr Trp Val Pro Ile Leu Thr Val
                 635                 640                 645

 Ile Val Gly Ser Tyr Leu Ile Ala His Gly Phe Phe Ser Val Tyr
                 650                 655                 660

 Gly Met Cys Val Asp Thr Leu Phe Leu Cys Phe Leu Glu Asp Leu
                 665                 670                 675

 Glu Arg Asn Asp Gly Ser Ala Glu Arg Pro Tyr Phe Met Ser Ser
                 680                 685                 690

 Thr Leu Lys Lys Leu Leu Asn Lys Thr Asn Lys Lys Ala Ala Glu
                 695                 700                 705

 Ser


<210> 5880
<211> 1508
<212> DNA
<213> Homo sapien

<400> 5880
 gctggaggag cctcgaggct gaggctgccg gggggctgtg ggctaccggg 50

 ccgccggcgc ctcagcgatg ttttactcag ggctcctcac tgagggcggc 100

 cgcaaggaga ccgacatgcg ggaggcggcg tcactgcgac agcagcgccg 150

 gatgaagcag gcggtgcagt tcatccacaa ggactccgcc gacctgctgc 200

 ccctggacgg cctcaagaag ctgggctcgt ccaaggacat gcaacctcat 250

 aatattctgc agaggcgcct catggaaacc aacctgtcta agctccgaag 300

 cggtccccgt gtcccttggg cctctaagac gaacaaactc aatcaggcta 350

 agtctgaggg gctaaagaag tctgaggagg atgacatgat tttggtttct 400

 tgccagtgtg ctggaaagga tgtgaaagcc ttggttgaca caggctgcct 450

 atataatctc atctctttgg cctgtgtgga cagattggga ctcaaggagc 500

 atgtcaaatc ccacaagcat gaaggagaaa agctttctct accccggcat 550

 ctcaaagtag tgggccagat tgagcaccta gtgatcacac tgggctccct 600

 ccgcctggac tgcccagcag ctgtggttga tgacaatgag aaaaacttgt 650

 cccttggtct acagactctc cgatctctga agtgcatcat aaacttggat 700

 aagcaccggc tgatcatggg gaagacagac aaggaagaaa tcccttttgt 750

 ggagacagtc tctttgaatg aagacaacac ttcagaagca taactacagc 800

 ctgcagcatg tctgcacgtg tgcatgcata cacaccgggt tgacagattg 850

 agaaaactgg gtttgaacca aatgccgtag tgacttgctg tggaccaagt 900

 ccttccatct aatagaagct ccaggggctc cttcccattc agacctctct 950

 agactatagt ctatgcttag agatcttgtc tggttatggc cattgttttt 1000

 tactactttg atcacttaac ttatagacct tttttgacac tgccagtctc 1050

 acttgtggcc tatttctctg cttcttccag gaatttgctt ttattagtca 1100

 agtatagggg ctgccaggtt ctgtgtctcc atagatatat gtgcttcttt 1150

 tcctatagct aaatgtataa taaacaggaa cctgaccttt acctcctttc 1200

 agctgtttca aacaggtgcc aggataccta tgtcttagaa ttagagtttc 1250

 ttcaaattga ttcattgatt tctcaagtat ggattatgtg aaagagccca 1300

 gggacattat ccattacagt ctaactcttt catttaaagg tccagagagg 1350

 caagtgaatt gtctaagttc atatattagg tcagtgactg aagggaccaa 1400

 gaacgcagac ctgatttcca agccaagact cccatgctgc ctcatttgta 1450

 ttcaagcctt taacaggagg gcaaagaggt gagaatgtgt taaaaaaaaa 1500

 aaaaaaaa 1508

<210> 5881
<211> 241
<212> PRT
<213> Homo sapien

<400> 5881
 Met Phe Tyr Ser Gly Leu Leu Thr Glu Gly Gly Arg Lys Glu Thr
   1               5                  10                  15

 Asp Met Arg Glu Ala Ala Ser Leu Arg Gln Gln Arg Arg Met Lys
                  20                  25                  30

 Gln Ala Val Gln Phe Ile His Lys Asp Ser Ala Asp Leu Leu Pro
                  35                  40                  45

 Leu Asp Gly Leu Lys Lys Leu Gly Ser Ser Lys Asp Met Gln Pro
                  50                  55                  60

 His Asn Ile Leu Gln Arg Arg Leu Met Glu Thr Asn Leu Ser Lys
                  65                  70                  75

 Leu Arg Ser Gly Pro Arg Val Pro Trp Ala Ser Lys Thr Asn Lys
                  80                  85                  90

 Leu Asn Gln Ala Lys Ser Glu Gly Leu Lys Lys Ser Glu Glu Asp
                  95                 100                 105

 Asp Met Ile Leu Val Ser Cys Gln Cys Ala Gly Lys Asp Val Lys
                 110                 115                 120

 Ala Leu Val Asp Thr Gly Cys Leu Tyr Asn Leu Ile Ser Leu Ala
                 125                 130                 135

 Cys Val Asp Arg Leu Gly Leu Lys Glu His Val Lys Ser His Lys
                 140                 145                 150

 His Glu Gly Glu Lys Leu Ser Leu Pro Arg His Leu Lys Val Val
                 155                 160                 165

 Gly Gln Ile Glu His Leu Val Ile Thr Leu Gly Ser Leu Arg Leu
                 170                 175                 180

 Asp Cys Pro Ala Ala Val Val Asp Asp Asn Glu Lys Asn Leu Ser
                 185                 190                 195

 Leu Gly Leu Gln Thr Leu Arg Ser Leu Lys Cys Ile Ile Asn Leu
                 200                 205                 210

 Asp Lys His Arg Leu Ile Met Gly Lys Thr Asp Lys Glu Glu Ile
                 215                 220                 225

 Pro Phe Val Glu Thr Val Ser Leu Asn Glu Asp Asn Thr Ser Glu
                 230                 235                 240

 Ala


<210> 5882
<211> 808
<212> DNA
<213> Homo sapien

<400> 5882
 tgctcccttg ggctctagag aggaggcccc tcttagccct cagcccctcc 50

 ttcctctcta tcttaaagta atttgatcct caggaatttg ttccgccctc 100

 atctggcccg gccaaatccc gatttgacaa atgccaggaa aaggaaactg 150

 ttgagaaacc gaaactactg gggaaaggga gggctcactg agtaaccatc 200

 ccagtaaccc gaccgccgct ggtcttcgct ggacaccatg agtcacactg 250

 tccaaacctt cttctctcct gtcaacagtg gccagccccc caactatgag 300

 atgctcaagg aggagcacga ggtggctgtg ctgggggggc cccacaaccc 350

 tgctcccccg acgtccaccg tgatccacat ccgcagcgag acctccgtgc 400

 ccgaccatgt cgtctggtcc ctgttcaaca ccctcttcat gaacccctgc 450

 tgcctgggct tcatagcatt cgcctactcc gtgaagtcta gggacaggaa 500

 gatggttggc gacgtgaccg gggcccaggc ctatgcctcc accgccaagt 550

 gcctgaacat ctgggccctg attctgggca tcctcatgac cattctgctc 600

 atcgtcatcc cagtgctgat cttccaggcc tatggataga tcaggaggca 650

 tcactgaggc caggagctct gcccatgacc tgtatcccac gtactccaac 700

 ttccattcct cgccctgccc ccggagccga gtcctgtatc agccctttat 750

 cctcacacgc ttttctacaa tggcattcaa taaagtgcac gtgtttctgg 800

 tgctgctg 808

<210> 5883
<211> 133
<212> PRT
<213> Homo sapien

<400> 5883
 Met Ser His Thr Val Gln Thr Phe Phe Ser Pro Val Asn Ser Gly
   1               5                  10                  15

 Gln Pro Pro Asn Tyr Glu Met Leu Lys Glu Glu His Glu Val Ala
                  20                  25                  30

 Val Leu Gly Gly Pro His Asn Pro Ala Pro Pro Thr Ser Thr Val
                  35                  40                  45

 Ile His Ile Arg Ser Glu Thr Ser Val Pro Asp His Val Val Trp
                  50                  55                  60

 Ser Leu Phe Asn Thr Leu Phe Met Asn Pro Cys Cys Leu Gly Phe
                  65                  70                  75

 Ile Ala Phe Ala Tyr Ser Val Lys Ser Arg Asp Arg Lys Met Val
                  80                  85                  90

 Gly Asp Val Thr Gly Ala Gln Ala Tyr Ala Ser Thr Ala Lys Cys
                  95                 100                 105

 Leu Asn Ile Trp Ala Leu Ile Leu Gly Ile Leu Met Thr Ile Leu
                 110                 115                 120

 Leu Ile Val Ile Pro Val Leu Ile Phe Gln Ala Tyr Gly
                 125                 130

<210> 5884
<211> 1544
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1358
<223> Unknown base

<400> 5884
 gcacgagttg ggaggtgtag cgcggctctg aacgcgctga gggccgttga 50

 gtgtcgcagg cggcgagggc gcgagtgagg agcagaccca ggcatcgcgc 100

 gccgagaagg ccgggcgtcc ccacactgaa ggtccggaaa ggcgacttcc 150

 gggggctttg gcacctggcg gaccctcccg gagcgtcggc acctgaacgc 200

 gaggcgctcc attgcgcgtg cgcgttgagg ggcttcccgc acctgatcgc 250

 gagaccccaa cggctggtgg cgtcgcctgc gcgtctcggc tgagctggcc 300

 atggcgcagc tgtgcgggct gaggcggagc cgggcgtttc tcgccctgct 350

 gggatcgctg ctcctctctg gggtcctggc ggccgaccga gaacgcagca 400

 tccacgactt ctgcctggtg tcgaaggtgg tgggcagatg ccgggcctcc 450

 atgcctaggt ggtggtacaa tgtcactgac ggatcctgcc agctgtttgt 500

 gtatgggggc tgtgacggaa acagcaataa ttacctgacc aaggaggagt 550

 gcctcaagaa atgtgccact gtcacagaga atgccacggg tgacctggcc 600

 accagcagga atgcagcgga ttcctctgtc ccaagtgctc ccagaaggca 650

 ggattctgaa gaccactcca gcgatatgtt caactatgaa gaatactgca 700

 ccgccaacgc agtcactggg ccttgccgtg catccttccc acgctggtac 750

 tttgacgtgg agaggaactc ctgcaataac ttcatctatg gaggctgccg 800

 gggcaataag aacagctacc gctctgagga ggcctgcatg ctccgctgct 850

 tccgccagca ggagaatcct cccctgcccc ttggctcaaa ggtggtggtt 900

 ctggcggggc tgttcgtgat ggtgttgatc ctcttcctgg gagcctccat 950

 ggtctacctg atccgggtgg cacggaggaa ccaggagcgt gccctgcgca 1000

 ccgtctggag ctccggagat gacaaggagc agctggtgaa gaacacatat 1050

 gtcctgtgac cgccctgtcg ccaagaggac tggggaaggg aggggagact 1100

 atgtgtgagc tttttttaaa tagagggatt gactcggatt tgagtgatca 1150

 ttagggctga ggtctgtttc tctgggaggt aggacggctg cttcctggtc 1200

 tggcagggat gggtttgctt tggaaatcct ctaggaggct cctcctcgca 1250

 tggcctgcag tctggcagca gccccgagtt gtttcctcgc tgatcgattt 1300

 ctttcctcca ggtagagttt tctttgctta tgttgaattc cattgcctcc 1350

 ttttctcnat cacagaagtg atgttggaat cgtttctttt gtttgtctga 1400

 tttatggttt ttttaagtat aaacaaaagt tttttattag cattctgaaa 1450

 gaaggaaagt aaaatgtaca agtttaataa aaaggggcct tcccctttag 1500

 aataaatttc cagcatgttg ctttcaaaaa aaaaaaaaaa aaaa 1544

<210> 5885
<211> 252
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1358
<223> Unknown amino acid

<400> 5885
 Met Ala Gln Leu Cys Gly Leu Arg Arg Ser Arg Ala Phe Leu Ala
   1               5                  10                  15

 Leu Leu Gly Ser Leu Leu Leu Ser Gly Val Leu Ala Ala Asp Arg
                  20                  25                  30

 Glu Arg Ser Ile His Asp Phe Cys Leu Val Ser Lys Val Val Gly
                  35                  40                  45

 Arg Cys Arg Ala Ser Met Pro Arg Trp Trp Tyr Asn Val Thr Asp
                  50                  55                  60

 Gly Ser Cys Gln Leu Phe Val Tyr Gly Gly Cys Asp Gly Asn Ser
                  65                  70                  75

 Asn Asn Tyr Leu Thr Lys Glu Glu Cys Leu Lys Lys Cys Ala Thr
                  80                  85                  90

 Val Thr Glu Asn Ala Thr Gly Asp Leu Ala Thr Ser Arg Asn Ala
                  95                 100                 105

 Ala Asp Ser Ser Val Pro Ser Ala Pro Arg Arg Gln Asp Ser Glu
                 110                 115                 120

 Asp His Ser Ser Asp Met Phe Asn Tyr Glu Glu Tyr Cys Thr Ala
                 125                 130                 135

 Asn Ala Val Thr Gly Pro Cys Arg Ala Ser Phe Pro Arg Trp Tyr
                 140                 145                 150

 Phe Asp Val Glu Arg Asn Ser Cys Asn Asn Phe Ile Tyr Gly Gly
                 155                 160                 165

 Cys Arg Gly Asn Lys Asn Ser Tyr Arg Ser Glu Glu Ala Cys Met
                 170                 175                 180

 Leu Arg Cys Phe Arg Gln Gln Glu Asn Pro Pro Leu Pro Leu Gly
                 185                 190                 195

 Ser Lys Val Val Val Leu Ala Gly Leu Phe Val Met Val Leu Ile
                 200                 205                 210

 Leu Phe Leu Gly Ala Ser Met Val Tyr Leu Ile Arg Val Ala Arg
                 215                 220                 225

 Arg Asn Gln Glu Arg Ala Leu Arg Thr Val Trp Ser Ser Gly Asp
                 230                 235                 240

 Asp Lys Glu Gln Leu Val Lys Asn Thr Tyr Val Leu
                 245                 250

<210> 5886
<211> 2077
<212> DNA
<213> Homo sapien

<400> 5886
 ccgagcgcca gcgcggggaa ccgggaaaag gaaaccgtgt tgtgtacgta 50

 agattcagga aacgaaacca ggagccgcgg gtgttggcgc aaaggttact 100

 cccagaccct tttccggctg acttctgaga aggttgcgca cagctgtgcc 150

 cggcagtcta gaggcgcaga agaggaagcc atcgcctggc cccggctctc 200

 tggaccttgt ctcgctcggg agcggaaaca gcggcagcca gagaactgtt 250

 ttaatcatgg acaaacaaaa ctcacagatg aatgcttctc acccggaaac 300

 aaacttgcca gttgggtatc ctcctcagta tccaccgaca gcattccaag 350

 gacctccagg atatagtggc taccctgggc cccaggtcag ctacccaccc 400

 ccaccagccg gccattcagg tcctggccca gctggctttc ctgtcccaaa 450

 tcagccagtg tataatcagc cagtatataa tcagccagtt ggagctgcag 500

 gggtaccatg gatgccagcg ccacagcctc cattaaactg tccacctgga 550

 ttagaatatt taagtcagat agatcagata ctgattcatc agcaaattga 600

 acttctggaa gttttaacag gttttgaaac taataacaaa tatgaaatta 650

 agaacagctt tggacagagg gtttactttg cagcggaaga tactgattgc 700

 tgtacccgaa attgctgtgg gccatctaga ccttttacct tgaggattat 750

 tgataatatg ggtcaagaag tcataactct ggagagacca ctaagatgta 800

 gcagctgttg ttgtccctgc tgccttcagg agatagaaat ccaagctcct 850

 cctggtgtac caataggtta tgttattcag acttggcacc catgtctacc 900

 aaagtttaca attcaaaatg agaaaagaga ggatgtacta aaaataagtg 950

 gtccatgtgt tgtgtgcagc tgttgtggag atgttgattt tgagattaaa 1000

 tctcttgatg aacagtgtgt ggttggcaaa atttccaagc actggactgg 1050

 aattttgaga gaggcattta cagacgctga taactttgga atccagttcc 1100

 ctttagacct tgatgttaaa atgaaagctg taatgattgg tgcctgtttc 1150

 ctcattgact tcatgttttt tgaaagcact ggcagccagg aacaaaaatc 1200

 aggagtgtgg tagtggatta gtgaaagtct cctcaggaaa tctgaagtct 1250

 gtatattgat tgagactatc taaactcata cctgtatgaa ttaagctgta 1300

 aggcctgtag ctctggttgt atacttttgc ttttcaaatt atagtttatc 1350

 ttctgtataa ctgatttata aaggtttttg tacatttttt aatactcatt 1400

 gtcaatttga gaaaaaggac atatgagttt ttgcatttat taatgaaact 1450

 tcctttgaaa aactgctttg aattatgatc tctgattcat tgtccatttt 1500

 actaccaaat attaactaag gccttattaa tttttatata aattatatct 1550

 tgtcctatta aatctagtta caatttattt catgcataag agctaatgtt 1600

 attttgcaaa tgccatatat tcaaaaaagc tcaaagataa ttttctttac 1650

 tattatgttc aaataatatt caatatgcat attatcttta aaaagttaaa 1700

 tgttttttta atcttcaaga aatcatgcta cacttaactt ctcctagaag 1750

 ctaatctata ccataatatt ttcatattca caagatatta aattaccaat 1800

 tttcaaatta ttgttagtaa agaacaaaat gattctctcc caaagaaaga 1850

 cacattttaa atactccttc actctaaaac tctggtatta taacttttga 1900

 aagttaatat ttctacatga aatgtttagc tcttacactc tatccttcct 1950

 agaaaatggt aattgagatt actcagatat taattaaata caatatcata 2000

 tatatattca cagagtataa acctaaataa tgatctatta gattcaaata 2050

 tttgaaataa aaacttgatt tttttgt 2077

<210> 5887
<211> 318
<212> PRT
<213> Homo sapien

<400> 5887
 Met Asp Lys Gln Asn Ser Gln Met Asn Ala Ser His Pro Glu Thr
   1               5                  10                  15

 Asn Leu Pro Val Gly Tyr Pro Pro Gln Tyr Pro Pro Thr Ala Phe
                  20                  25                  30

 Gln Gly Pro Pro Gly Tyr Ser Gly Tyr Pro Gly Pro Gln Val Ser
                  35                  40                  45

 Tyr Pro Pro Pro Pro Ala Gly His Ser Gly Pro Gly Pro Ala Gly
                  50                  55                  60

 Phe Pro Val Pro Asn Gln Pro Val Tyr Asn Gln Pro Val Tyr Asn
                  65                  70                  75

 Gln Pro Val Gly Ala Ala Gly Val Pro Trp Met Pro Ala Pro Gln
                  80                  85                  90

 Pro Pro Leu Asn Cys Pro Pro Gly Leu Glu Tyr Leu Ser Gln Ile
                  95                 100                 105

 Asp Gln Ile Leu Ile His Gln Gln Ile Glu Leu Leu Glu Val Leu
                 110                 115                 120

 Thr Gly Phe Glu Thr Asn Asn Lys Tyr Glu Ile Lys Asn Ser Phe
                 125                 130                 135

 Gly Gln Arg Val Tyr Phe Ala Ala Glu Asp Thr Asp Cys Cys Thr
                 140                 145                 150

 Arg Asn Cys Cys Gly Pro Ser Arg Pro Phe Thr Leu Arg Ile Ile
                 155                 160                 165

 Asp Asn Met Gly Gln Glu Val Ile Thr Leu Glu Arg Pro Leu Arg
                 170                 175                 180

 Cys Ser Ser Cys Cys Cys Pro Cys Cys Leu Gln Glu Ile Glu Ile
                 185                 190                 195

 Gln Ala Pro Pro Gly Val Pro Ile Gly Tyr Val Ile Gln Thr Trp
                 200                 205                 210

 His Pro Cys Leu Pro Lys Phe Thr Ile Gln Asn Glu Lys Arg Glu
                 215                 220                 225

 Asp Val Leu Lys Ile Ser Gly Pro Cys Val Val Cys Ser Cys Cys
                 230                 235                 240

 Gly Asp Val Asp Phe Glu Ile Lys Ser Leu Asp Glu Gln Cys Val
                 245                 250                 255

 Val Gly Lys Ile Ser Lys His Trp Thr Gly Ile Leu Arg Glu Ala
                 260                 265                 270

 Phe Thr Asp Ala Asp Asn Phe Gly Ile Gln Phe Pro Leu Asp Leu
                 275                 280                 285

 Asp Val Lys Met Lys Ala Val Met Ile Gly Ala Cys Phe Leu Ile
                 290                 295                 300

 Asp Phe Met Phe Phe Glu Ser Thr Gly Ser Gln Glu Gln Lys Ser
                 305                 310                 315

 Gly Val Trp


<210> 5888
<211> 1297
<212> DNA
<213> Homo sapien

<400> 5888
 gcgcaggcgt ggggctctct ccttgtcagt cggcgccgcg tgcgggctgg 50

 tggctctgtg gcagcggcgg cggcaggact ccggcactat gagcggcttc 100

 agcaccgagg agcgcgccgc gcccttctcc ctggagtacc gagtcttcct 150

 caaaaatgag aaaggacaat atatatctcc atttcatgat attccaattt 200

 atgcagataa ggatgtgttt cacatggtag ttgaagtacc acgctggtct 250

 aatgcaaaaa tggagattgc tacaaaggac cctttaaacc ctattaaaca 300

 agatgtgaaa aaaggaaaac ttcgctatgt tgcgaatttg ttcccgtata 350

 aaggatatat ctggaactat ggtgccatcc ctcagacttg ggaagaccca 400

 gggcacaatg ataaacatac tggctgttgt ggtgacaatg acccaattga 450

 tgtgtgtgaa attggaagca aggtatgtgc aagaggtgaa ataattggcg 500

 tgaaagttct aggcatattg gctatgattg acgaagggga aaccgactgg 550

 aaagtcattg ccattaatgt ggatgatcct gatgcagcca attataatga 600

 tatcaatgat gtcaaacggc tgaaacctgg ctacttagaa gctactgtgg 650

 actggtttag aaggtataag gttcctgatg gaaaaccaga aaatgagttt 700

 gcgtttaatg cagaatttaa agataaggac tttgccattg atattattaa 750

 aagcactcat gaccattgga aagcattagt gactaagaaa acgaatggaa 800

 aaggaatcag ttgcatgaat acaactttgt ctgagagccc cttcaagtgt 850

 gatcctgatg ctgccagagc cattgtggat gctttaccac caccctgtga 900

 atctgcctgc acagtaccaa cagacgtgga taagtggttc catcaccaga 950

 aaaactaatg agatttctct ggaatacaag ctgatattgc tacatcgtgt 1000

 tcatctggat gtattagaag taaaagtagt agcttttcaa agctttaaat 1050

 ttgtagaact catctaacta aagtaaattc tgctgtgact aatccaatat 1100

 actcagaatg ttatccatct aaagcatttt tcatatctca actaagataa 1150

 cttttagcac atgcttaaat atcaaagcag ttgtcatttg gaagtcactt 1200

 gtgaatagat gtgcaagggg agcacatatt ggatgtatat gttaccatat 1250

 gttaggaaat aaaattattt tgctgaaact tggaaaaaaa aaaaaaa 1297

<210> 5889
<211> 289
<212> PRT
<213> Homo sapien

<400> 5889
 Met Ser Gly Phe Ser Thr Glu Glu Arg Ala Ala Pro Phe Ser Leu
   1               5                  10                  15

 Glu Tyr Arg Val Phe Leu Lys Asn Glu Lys Gly Gln Tyr Ile Ser
                  20                  25                  30

 Pro Phe His Asp Ile Pro Ile Tyr Ala Asp Lys Asp Val Phe His
                  35                  40                  45

 Met Val Val Glu Val Pro Arg Trp Ser Asn Ala Lys Met Glu Ile
                  50                  55                  60

 Ala Thr Lys Asp Pro Leu Asn Pro Ile Lys Gln Asp Val Lys Lys
                  65                  70                  75

 Gly Lys Leu Arg Tyr Val Ala Asn Leu Phe Pro Tyr Lys Gly Tyr
                  80                  85                  90

 Ile Trp Asn Tyr Gly Ala Ile Pro Gln Thr Trp Glu Asp Pro Gly
                  95                 100                 105

 His Asn Asp Lys His Thr Gly Cys Cys Gly Asp Asn Asp Pro Ile
                 110                 115                 120

 Asp Val Cys Glu Ile Gly Ser Lys Val Cys Ala Arg Gly Glu Ile
                 125                 130                 135

 Ile Gly Val Lys Val Leu Gly Ile Leu Ala Met Ile Asp Glu Gly
                 140                 145                 150

 Glu Thr Asp Trp Lys Val Ile Ala Ile Asn Val Asp Asp Pro Asp
                 155                 160                 165

 Ala Ala Asn Tyr Asn Asp Ile Asn Asp Val Lys Arg Leu Lys Pro
                 170                 175                 180

 Gly Tyr Leu Glu Ala Thr Val Asp Trp Phe Arg Arg Tyr Lys Val
                 185                 190                 195

 Pro Asp Gly Lys Pro Glu Asn Glu Phe Ala Phe Asn Ala Glu Phe
                 200                 205                 210

 Lys Asp Lys Asp Phe Ala Ile Asp Ile Ile Lys Ser Thr His Asp
                 215                 220                 225

 His Trp Lys Ala Leu Val Thr Lys Lys Thr Asn Gly Lys Gly Ile
                 230                 235                 240

 Ser Cys Met Asn Thr Thr Leu Ser Glu Ser Pro Phe Lys Cys Asp
                 245                 250                 255

 Pro Asp Ala Ala Arg Ala Ile Val Asp Ala Leu Pro Pro Pro Cys
                 260                 265                 270

 Glu Ser Ala Cys Thr Val Pro Thr Asp Val Asp Lys Trp Phe His
                 275                 280                 285

 His Gln Lys Asn


<210> 5890
<211> 5786
<212> DNA
<213> Homo sapien

<400> 5890
 tcccagcttt tcaaaagttt attttaagtt tggagactag acaaggtcat 50

 actggtttta catcctacgt gatataagta tatatacaaa gaaaaaaaca 100

 acattggaat attacacagc ttgaaggttt gcaaaggtta tttgtgtctt 150

 agttatttct gcacttaatg acacatcaga cgcattgagt atatttcata 200

 agttgttgac tagcaaagat acaatcatta gtaacccaag tcttcaaaat 250

 tcacaccaaa ctttatgaag tcattcagaa agagaaagtc aatcctaaaa 300

 ttaaaattgg caactatgat aaataccttc aaaaggatgt agatataatg 350

 gagatgttta aaagtttagt ttcattaatt gtaaaattag catgttatat 400

 ttactcaata tagtgaagac tagggggatt cttacatgta ttctacttat 450

 gggactgtac tgggtttagg ggggaattta catagaataa atttacttca 500

 ctttcatggt catcgacatg aatgacacaa aagctacttc ataatactac 550

 tttacaatag ttttcaacat ttccatatgg tgcgacccct ttgctctcat 600

 caattttggg tgtcatgaga acaataggta tcccgttgga catgatgtat 650

 tgcgaagagc atataaagca gagggaaaat gaaaaagcaa gagaaactca 700

 tttcaatgct ttttctaaaa ggtaacaaat ataattttaa tcaacttcct 750

 tggaaaatat ttttaaaaca ggtatcaata gaaaaaatta caaaacatca 800

 tatgaagcta taaataattt tgaaaaacta tatcatcata aagcgtaagt 850

 aataatctta aaaatacact cttaagaagg tatgtaattt gcaaaggaaa 900

 atggctagat atctgatggg acagtaaacc ttgaaagaaa ctggctaaag 950

 agtaagtgtg tgtatatttc tgaacctaag taattatttg tcacgacttt 1000

 aaaatttagc cagttacaaa tattttaaaa tcctaacttt aaagttatct 1050

 aaaaaaggca atatggagga aatagtaatt ttgtttttga aagatgttga 1100

 aaactgatca ccatttcaga ggcttcaaat tcataatttc ataataagaa 1150

 caagaagtag aaagcatatg ggcaaggaac aaatatgtgg ccagccagtc 1200

 cccttagacg aactaatttt gttcttatta aaaatgccaa tacaattgac 1250

 tttctcttta aattcttcac tatgattgaa gaccactcca tatatacatc 1300

 attaagaaat gctgttaaca catggacaga caagacagta acagtctagt 1350

 ggcttttgtt atgcagcaca aatattaaag gaaaaaaata gcagtgttgc 1400

 gtaggatctt aacatttcat acacatacca tcctttcttt tccaatacac 1450

 ttaatttaaa actccaataa ttctgtctaa gccttataaa ataaatactt 1500

 gtaaagctta taaattagat gttgaagact tttatggagg cagtgtgagc 1550

 tttaatttga gagacatgtc aatgaaacct ccagtatcaa taacaaattg 1600

 ttatgataat tgcttatttt ttcaggacct ttgaagcaaa ataaatagaa 1650

 atcagttttc atcttgaaaa tggtttacta ctttgtcatt agtaaacact 1700

 ttgcttctca caaataactc cacctgtgcc ttcctgggaa actaccacca 1750

 gtttcaaatc tcaataagat gttagtttca caggaaatgt ggagctgaac 1800

 aaagaaatga tgagtatgct tggccgaact atgcagcact atattaatat 1850

 ttctttgcta aatttttata aaataaacaa ataagccgat tttttaaagt 1900

 aaatataagg atatgtaatt accatctaaa tgaagattta aatttaaaga 1950

 gacatatata ttttttgttc ttttgtgcaa actgagagta tgggattctt 2000

 tatgaagcaa ttatttggaa attaaatagt tatggcttcc ttcaaaaata 2050

 aaactgcaga tttaattaac gaatattaaa tacagatcaa tctactgata 2100

 ggcagtcatg ttctacatat atgagtaaac atgacacttc ttttagtcaa 2150

 ctaataggaa attcaattag aaaaaaattg aattattcag gtaatataca 2200

 atattaagaa tgtagaatag aactaaaaga aaaagaagtc acataatctc 2250

 ttattagaaa taatgaaagt aaaatgagaa ttataatatc agtactgcat 2300

 gttacatatt cttctttaaa attttgtaat aaacattgac agtgtttggt 2350

 aggcacaggg aaacaggata acgtagagtc attacagaag aaaaaaactt 2400

 attgctaaca ttgcagtatt ccttttatca gaattaggtg agtattgatt 2450

 gtaaaagctc tatcaactct tgctcttatt tgatgacttt gagacttttt 2500

 tactcttgct ataaaaagaa ggctactttc tttccctaat atatttctac 2550

 caatgcgaat aattcaggaa acaatgagag aaaagtaatt cacacttaat 2600

 gtgttgttac ttaagagatt tgacggataa aataaaatca aattaaatca 2650

 ttgaaaaggc aggcttagac ccccttaaaa acaccgttag ttgcctacca 2700

 taatttgagc actttttcat gaaaaaaaaa aaaaaaccat tcagtttcct 2750

 acagattttg cacagttcat tccatggaga tacttttagg gaaataggga 2800

 agagggttgt gaaatgtagc ctcccctcat tcctcctctg tgcagcccag 2850

 cagctctgac cgcaatgtga tcctcccgta ccaggaccaa ggaaggattc 2900

 ttatgtgtcg tgcatagatg ggagggtcga tgacattttt tctgtgagtg 2950

 tcattgtcaa aatttccctg gaaaacctaa taaagaagag cagaaaaatg 3000

 tcagtcacct cgtgccgaat tcggcacgag cggacgtgct agatcttcac 3050

 gaggctgggg gcgaagattt cgccatggat gaggatgggg acgagagcat 3100

 tcacaaactg aaagaaaaag cgaagaaacg gaagggtcgc ggctttggct 3150

 ccgaagaggg gtcccgagcg cggatgcgtg aggattatga cagcgtggag 3200

 caggatggcg atgaacccgg accacaacgc tctgttgaag gctggattct 3250

 ctttgtaact ggagtccatg aggaagccac cgaagaagac atacacgaca 3300

 aattcgcaga atatggggaa attaaaaaca ttcatctcaa cctcgacagg 3350

 cgaacaggat atctgaaggg gtatactcta gttgaatatg aaacatacaa 3400

 ggaagcccag gctgctatgg agggactcaa tggccaggat ttgatgggac 3450

 agcccatcag cgttgactgg tgttttgttc ggggtccacc aaaaggcaag 3500

 aggagaggtg gccgaagacg cagcagaagt ccagaccgga gacgtcgctg 3550

 acaggtcctc tgttgtccag gtgttctctt caagattcca tttgaccatg 3600

 cagccttgga caaataggac tggggtggaa cttgctgtgt ttatatttaa 3650

 tctcttaccg tatatgcgta gtatttgagt tgcgaataaa tgttccattt 3700

 ttgttttcta catttaatgt tactttcctg tcctaaaatt gaaagttcta 3750

 aagcatagca aggctgtatg gatcattgtg aagatacttc tagggactga 3800

 actctatgta tttctttttt ttcttttttt tgagatagag tcttgctgtg 3850

 ttacccaggg tggattgcag ctgatcatag ctcactgcag cttcaaactc 3900

 ttgggctcaa gccatccttc tgcctcactg tccctagtag ttgggattac 3950

 aggcacatgc caccatgccc agctaaattt ttaatatttt tgtagagatg 4000

 gggtcttgct gtgttacctg ggctagttat gtgagtttct atattagaca 4050

 tagtctcaag tttcaagtag gggtttaaag tagagacact ggtcagtatt 4100

 tcttttttgg ggggaactag gagagcagga gtagaagtga gatgttaaga 4150

 tcttatggca ctaaagactt actattctgt tcctacatac tctgttagga 4200

 tcagatagat gttatagaaa tgccttttgt ttctcctgcc cttcttgatg 4250

 tcacagtttt ttgtacttcc agctgtctaa aggcatgaat ctcctcttgg 4300

 agcattctcc cagacccttc tttagaagag tctatactaa gttcttggtg 4350

 ccctcttcgg cagccaaggg tgaaggcccc atagaggaga ggatccaaag 4400

 gagcattgag gaggcccaag aggaaaagga tgtggctcag gctgggaggg 4450

 acttcagtta gcatggtggg ggagaaccag taccacatac ccagtaggta 4500

 ataaggtgtc cagcagagga tgaaggtcag caagataagc agggccagtc 4550

 tcagggcccg gagacgaaca cggggacaat tgtcaaagga gcgggggagg 4600

 gcaaattcac cagcaggggc taggaattta gaaaatatac tgtaattcag 4650

 acactcagct tctgatctga gtatagggtg aattgatgga ggggcatagc 4700

 tagtgagaca gagctcgcct cctacaagga ggagaatgtt gcaaaccgtt 4750

 ttccccttcc caacctggga ctatatgatt tcttaccccc agggattatg 4800

 atagaaatat gaagccacca agtctagact tgatggtgtt caagaataaa 4850

 taatactgat tgcctcccta gtccttgtcc agctaactca gctgtttata 4900

 attgaaggga ttcaacaaaa ttatctctag catcaggtgc tagacatggt 4950

 tagaatctca ccatggttta gtgactggta gatagctatt aggtaggtag 5000

 ataaataaat gatgctagag gcaacaggtc tagggttaag gattaaggcc 5050

 tgggaattgg agtctcacca tggctcccct tccttgtctg gggcctggac 5100

 acactgagga caatgcggct atagcagatg gccatggcag tcagtggcag 5150

 cagaaagagg cagcagaagg tgaagaggtt ataggtggtc tcttgccatt 5200

 gagccttgaa gctgcctttg gtgacacact gagtgaaagg gactgggcca 5250

 gctcagtgga ccgtgtggaa caggaacagc tggagtggag ttgaggacta 5300

 ttagaactgg ttcccctcac cacccaacct acccacctat gtcatactgt 5350

 ctcctcccaa ttcatcctta attccaagtg aagcagcaca gtgctgagaa 5400

 acagtttcat ccatggtgcc atgttaaaga agttggaaat atatcttgaa 5450

 aatcctatct tccttttagg cttgaatatg atgctgaaca gtaagtttgt 5500

 taaatcttgg aacttaaaac aatcctgctt tctcaagtac tattctaaca 5550

 ttgcgcttta taagggatga tatttctacc acctcactca tatttttagc 5600

 tgaaatgatt ttcctggtat gtctgttatt ttgtggaaaa agaaatattg 5650

 tgtaaaatgg gtgctgccaa aattccaggc cattttgcag ggactctgaa 5700

 gtgaccttta gtagtaatag tcttatgtgc agtaactata atggtaaaga 5750

 atgttaaata ataaaattta acattttcca aatgct 5786

<210> 5891
<211> 158
<212> PRT
<213> Homo sapien

<400> 5891
 Met Asp Glu Asp Gly Asp Glu Ser Ile His Lys Leu Lys Glu Lys
   1               5                  10                  15

 Ala Lys Lys Arg Lys Gly Arg Gly Phe Gly Ser Glu Glu Gly Ser
                  20                  25                  30

 Arg Ala Arg Met Arg Glu Asp Tyr Asp Ser Val Glu Gln Asp Gly
                  35                  40                  45

 Asp Glu Pro Gly Pro Gln Arg Ser Val Glu Gly Trp Ile Leu Phe
                  50                  55                  60

 Val Thr Gly Val His Glu Glu Ala Thr Glu Glu Asp Ile His Asp
                  65                  70                  75

 Lys Phe Ala Glu Tyr Gly Glu Ile Lys Asn Ile His Leu Asn Leu
                  80                  85                  90

 Asp Arg Arg Thr Gly Tyr Leu Lys Gly Tyr Thr Leu Val Glu Tyr
                  95                 100                 105

 Glu Thr Tyr Lys Glu Ala Gln Ala Ala Met Glu Gly Leu Asn Gly
                 110                 115                 120

 Gln Asp Leu Met Gly Gln Pro Ile Ser Val Asp Trp Cys Phe Val
                 125                 130                 135

 Arg Gly Pro Pro Lys Gly Lys Arg Arg Gly Gly Arg Arg Arg Ser
                 140                 145                 150

 Arg Ser Pro Asp Arg Arg Arg Arg
                 155

<210> 5892
<211> 1921
<212> DNA
<213> Homo sapien

<400> 5892
 cctgttgctg atgctgccgt gcggtacttg tcatggagct ggcactgcgg 50

 cgctctcccg tcccgcggtg gttgctgctg ctgccgctgc tgctgggcct 100

 gaacgcagga gctgtcattg actggcccac agaggagggc aaggaagtat 150

 gggattatgt gacggtccgc aaggatgcct acatgttctg gtggctctat 200

 tatgccacca actcctgcaa gaacttctca gaactgcccc tggtcatgtg 250

 gcttcagggc ggtccaggcg gttctagcac tggatttgga aactttgagg 300

 aaattgggcc ccttgacagt gatctcaaac cacggaaaac cacctggctc 350

 caggctgcca gtctcctatt tgtggataat cccgtgggca ctgggttcag 400

 ttatgtgaat ggtagtggtg cctatgccaa ggacctggct atggtggctt 450

 cagacatgat ggttctcctg aagaccttct tcagttgcca caaagaattc 500

 cagacagttc cattctacat tttctcagag tcctatggag gaaaaatggc 550

 agctggcatt ggtctagagc tttataaggc cattcagcga gggaccatca 600

 agtgcaactt tgcgggggtt gccttgggtg attcctggat ctcccccgtg 650

 gattcggtgc tctcctgggg accttacctg tacagcatgt ctcttctcga 700

 agacaaaggt ctggcagagg tgtctaaggt tgcagagcaa gtactgaatg 750

 ccgtaaataa ggggctctac agagaggcca cagagctgtg ggggaaagca 800

 gaaatgatca ttgaacagaa cacagatggg gtgaacttct ataacatctt 850

 aactaaaagc actcccacgt ctacaatgga gtcgagtcta gaattcacac 900

 agagccacct agtttgtctt tgtcagcgcc acgtgagaca cctacaacga 950

 gatgccttaa gccagctcat gaatggcccc atcagaaaga agctcaaaat 1000

 tattcctgag gatcaatcct ggggaggcca ggctaccaac gtctttgtga 1050

 acatggagga ggacttcatg aagccagtca ttagcattgt ggacgagttg 1100

 ctggaggcag ggatcaacgt gacggtgtat aatggacagc tggatctcat 1150

 cgtagatacc atgggtcagg aggcctgggt gcggaaactg aagtggccag 1200

 aactgcctaa attcagtcag ctgaagtgga aggccctgta cagtgaccct 1250

 aaatctttgg aaacatctgc ttttgtcaag tcctacaaga accttgcttt 1300

 ctactggatt ctgaaagctg gtcatatggt tccttctgac caaggggaca 1350

 tggctctgaa gatgatgaga ctggtgactc agcaagaata ggatggatgg 1400

 ggctggagat gagctggttt ggccttgggg cacagagctg agctgaggcc 1450

 gctgaagctg taggaagcgc cattcttccc tgtatctaac tggggctgtg 1500

 atcaagaagg ttctgaccag cttctgcaga ggataaaatc attgtctctg 1550

 gaggcaattt ggaaattatt tctgcttctt aaaaaaacct aagatttttt 1600

 aaaaaattga tttgttttga tcaaaataaa ggatgataat agatattatt 1650

 ttttcttatg acagaagcaa atgatgtgat ttatagaaaa actgggaaat 1700

 acaggtaccc aaagagtaaa tcaacatctg tataccccct tcccaggggt 1750

 aagcactgtt accaatttag catatgtcct tgcagaattt ttttttctat 1800

 atatacatat atatttttta ccaaaatgaa tcattactct atgttgtttt 1850

 actatttgtt tgacatatca gtatatctga aacacctttt catgtcaata 1900

 aatgttcttc tctaacatta a 1921

<210> 5893
<211> 452
<212> PRT
<213> Homo sapien

<400> 5893
 Met Glu Leu Ala Leu Arg Arg Ser Pro Val Pro Arg Trp Leu Leu
   1               5                  10                  15

 Leu Leu Pro Leu Leu Leu Gly Leu Asn Ala Gly Ala Val Ile Asp
                  20                  25                  30

 Trp Pro Thr Glu Glu Gly Lys Glu Val Trp Asp Tyr Val Thr Val
                  35                  40                  45

 Arg Lys Asp Ala Tyr Met Phe Trp Trp Leu Tyr Tyr Ala Thr Asn
                  50                  55                  60

 Ser Cys Lys Asn Phe Ser Glu Leu Pro Leu Val Met Trp Leu Gln
                  65                  70                  75

 Gly Gly Pro Gly Gly Ser Ser Thr Gly Phe Gly Asn Phe Glu Glu
                  80                  85                  90

 Ile Gly Pro Leu Asp Ser Asp Leu Lys Pro Arg Lys Thr Thr Trp
                  95                 100                 105

 Leu Gln Ala Ala Ser Leu Leu Phe Val Asp Asn Pro Val Gly Thr
                 110                 115                 120

 Gly Phe Ser Tyr Val Asn Gly Ser Gly Ala Tyr Ala Lys Asp Leu
                 125                 130                 135

 Ala Met Val Ala Ser Asp Met Met Val Leu Leu Lys Thr Phe Phe
                 140                 145                 150

 Ser Cys His Lys Glu Phe Gln Thr Val Pro Phe Tyr Ile Phe Ser
                 155                 160                 165

 Glu Ser Tyr Gly Gly Lys Met Ala Ala Gly Ile Gly Leu Glu Leu
                 170                 175                 180

 Tyr Lys Ala Ile Gln Arg Gly Thr Ile Lys Cys Asn Phe Ala Gly
                 185                 190                 195

 Val Ala Leu Gly Asp Ser Trp Ile Ser Pro Val Asp Ser Val Leu
                 200                 205                 210

 Ser Trp Gly Pro Tyr Leu Tyr Ser Met Ser Leu Leu Glu Asp Lys
                 215                 220                 225

 Gly Leu Ala Glu Val Ser Lys Val Ala Glu Gln Val Leu Asn Ala
                 230                 235                 240

 Val Asn Lys Gly Leu Tyr Arg Glu Ala Thr Glu Leu Trp Gly Lys
                 245                 250                 255

 Ala Glu Met Ile Ile Glu Gln Asn Thr Asp Gly Val Asn Phe Tyr
                 260                 265                 270

 Asn Ile Leu Thr Lys Ser Thr Pro Thr Ser Thr Met Glu Ser Ser
                 275                 280                 285

 Leu Glu Phe Thr Gln Ser His Leu Val Cys Leu Cys Gln Arg His
                 290                 295                 300

 Val Arg His Leu Gln Arg Asp Ala Leu Ser Gln Leu Met Asn Gly
                 305                 310                 315

 Pro Ile Arg Lys Lys Leu Lys Ile Ile Pro Glu Asp Gln Ser Trp
                 320                 325                 330

 Gly Gly Gln Ala Thr Asn Val Phe Val Asn Met Glu Glu Asp Phe
                 335                 340                 345

 Met Lys Pro Val Ile Ser Ile Val Asp Glu Leu Leu Glu Ala Gly
                 350                 355                 360

 Ile Asn Val Thr Val Tyr Asn Gly Gln Leu Asp Leu Ile Val Asp
                 365                 370                 375

 Thr Met Gly Gln Glu Ala Trp Val Arg Lys Leu Lys Trp Pro Glu
                 380                 385                 390

 Leu Pro Lys Phe Ser Gln Leu Lys Trp Lys Ala Leu Tyr Ser Asp
                 395                 400                 405

 Pro Lys Ser Leu Glu Thr Ser Ala Phe Val Lys Ser Tyr Lys Asn
                 410                 415                 420

 Leu Ala Phe Tyr Trp Ile Leu Lys Ala Gly His Met Val Pro Ser
                 425                 430                 435

 Asp Gln Gly Asp Met Ala Leu Lys Met Met Arg Leu Val Thr Gln
                 440                 445                 450

 Gln Glu


<210> 5894
<211> 3014
<212> DNA
<213> Homo sapien

<400> 5894
 cccccagaag cccatcagac tgcccccagc acacggaatg gatttctgag 50

 aaagaagccg aaacagaagg cccgtgggag tcagcatgcc gcgtggctgg 100

 gccgccccct tgctcctgct gctgctccag ggaggctggg gctgccccga 150

 cctcgtctgc tacaccgatt acctccagac ggtcatctgc atcctggaaa 200

 tgtggaacct ccaccccagc acgctcaccc ttacctggca agaccagtat 250

 gaagagctga aggacgaggc cacctcctgc agcctccaca ggtcggccca 300

 caatgccacg catgccacct acacctgcca catggatgta ttccacttca 350

 tggccgacga cattttcagt gtcaacatca cagaccagtc tggcaactac 400

 tcccaggagt gtggcagctt tctcctggct gagagcatca agccggctcc 450

 ccctttcaac gtgactgtga ccttctcagg acagtataat atctcctggc 500

 gctcagatta cgaagaccct gccttctaca tgctgaaggg caagcttcag 550

 tatgagctgc agtacaggaa ccggggagac ccctgggctg tgagtccgag 600

 gagaaagctg atctcagtgg actcaagaag tgtctccctc ctccccctgg 650

 agttccgcaa agactcgagc tatgagctgc aggtgcgggc agggcccatg 700

 cctggctcct cctaccaggg gacctggagt gaatggagtg acccggtcat 750

 ctttcagacc cagtcagagg agttaaagga aggctggaac cctcacctgc 800

 tgcttctcct cctgcttgtc atagtcttca ttcctgcctt ctggagcctg 850

 aagacccatc cattgtggag gctatggaag aagatatggg ccgtccccag 900

 ccctgagcgg ttcttcatgc ccctgtacaa gggctgcagc ggagacttca 950

 agaaatgggt gggtgcaccc ttcactggct ccagcctgga gctgggaccc 1000

 tggagcccag aggtgccctc caccctggag gtgtacagct gccacccacc 1050

 acggagcccg gccaagaggc tgcagctcac ggagctacaa gaaccagcag 1100

 agctggtgga gtctgacggt gtgcccaagc ccagcttctg gccgacagcc 1150

 cagaactcgg ggggctcagc ttacagtgag gagagggatc ggccatacgg 1200

 cctggtgtcc attgacacag tgactgtgct agatgcagag gggccatgca 1250

 cctggccctg cagctgtgag gatgacggct acccagccct ggacctggat 1300

 gctggcctgg agcccagccc aggcctagag gacccactct tggatgcagg 1350

 gaccacagtc ctgtcctgtg gctgtgtctc agctggcagc cctgggctag 1400

 gagggcccct gggaagcctc ctggacagac taaagccacc ccttgcagat 1450

 ggggaggact gggctggggg actgccctgg ggtggccggt cacctggagg 1500

 ggtctcagag agtgaggcgg gctcacccct ggccggcctg gatatggaca 1550

 cgtttgacag tggctttgtg ggctctgact gcagcagccc tgtggagtgt 1600

 gacttcacca gccccgggga cgaaggaccc ccccggagct acctccgcca 1650

 gtgggtggtc attcctccgc cactttcgag ccctggaccc caggccagct 1700

 aatgaggctg actggatgtc cagagctggc caggccactg ggccctgagc 1750

 cagagacaag gtcacctggg ctgtgatgtg aagacacctg cagcctttgg 1800

 tctcctggat gggcctttga gcctgatgtt tacagtgtct gtgtgtgtgt 1850

 gtgcatatgt gtgtgtgtgc atatgcatgt gtgtgtgtgt gtgtgtctta 1900

 ggtgcgcagt ggcatgtcca cgtgtgtgtg tgattgcacg tgcctgtggg 1950

 cctgggataa tgcccatggt actccatgca ttcacctgcc ctgtgcatgt 2000

 ctggactcac ggagctcacc catgtgcaca agtgtgcaca gtaaacgtgt 2050

 ttgtggtcaa cagatgacaa cagccgtcct ccctcctagg gtcttgtgtt 2100

 gcaagttggt ccacagcatc tccggggctt tgtgggatca gggcattgcc 2150

 tgtgactgag gcggagccca gccctccagc gtctgcctcc aggagctgca 2200

 agaagtccat attgttcctt atcacctgcc aacaggaagc gaaaggggat 2250

 ggagtgagcc catggtgacc tcgggaatgg caattttttg ggcggcccct 2300

 ggacgaaggt ctgaatcccg actctgatac cttctggctg tgctacctga 2350

 gccaagtcgc ctcccctctc tgggctagag tttccttatc cagacagtgg 2400

 ggaaggcatg acacacctgg gggaaattgg cgatgtcacc cgtgtacggt 2450

 acgcagccca gagcagaccc tcaataaacg tcagcttcct tccttctgcg 2500

 gccagagccg aggcgggcgg gggtgagaac atcaatcgtc agcgacagcc 2550

 tgggcacccg cggggccgtc ccgcctgcag agggccactc gggggggttt 2600

 ccaggcttaa aatcagtccg tttcgtctct tggaaacagc tccccaccaa 2650

 ccaagatttc tttttctaac ttctgctact aagtttttaa aaattccctt 2700

 tatgcaccca agagatattt attaaacacc aattacgtag caggccatgg 2750

 ctcatgggac ccaccccccg tggcactcat ggagggggct gcaggttgga 2800

 actatgcagt gtgctccggc cacacatcct gctgggcccc ctaccctgcc 2850

 ccaattcaat cctgccaata aatcctgtct tatttgttca tcctggagaa 2900

 ttgaagggag gtcaagttgt ttgtcaatga tttgtcagag aacctgttga 2950

 aatgtgaatt aagaagctaa gaaaataaaa aaaaaaaaaa aaaaaaaaaa 3000

 aaaaaaaaaa aaaa 3014

<210> 5895
<211> 538
<212> PRT
<213> Homo sapien

<400> 5895
 Met Pro Arg Gly Trp Ala Ala Pro Leu Leu Leu Leu Leu Leu Gln
   1               5                  10                  15

 Gly Gly Trp Gly Cys Pro Asp Leu Val Cys Tyr Thr Asp Tyr Leu
                  20                  25                  30

 Gln Thr Val Ile Cys Ile Leu Glu Met Trp Asn Leu His Pro Ser
                  35                  40                  45

 Thr Leu Thr Leu Thr Trp Gln Asp Gln Tyr Glu Glu Leu Lys Asp
                  50                  55                  60

 Glu Ala Thr Ser Cys Ser Leu His Arg Ser Ala His Asn Ala Thr
                  65                  70                  75

 His Ala Thr Tyr Thr Cys His Met Asp Val Phe His Phe Met Ala
                  80                  85                  90

 Asp Asp Ile Phe Ser Val Asn Ile Thr Asp Gln Ser Gly Asn Tyr
                  95                 100                 105

 Ser Gln Glu Cys Gly Ser Phe Leu Leu Ala Glu Ser Ile Lys Pro
                 110                 115                 120

 Ala Pro Pro Phe Asn Val Thr Val Thr Phe Ser Gly Gln Tyr Asn
                 125                 130                 135

 Ile Ser Trp Arg Ser Asp Tyr Glu Asp Pro Ala Phe Tyr Met Leu
                 140                 145                 150

 Lys Gly Lys Leu Gln Tyr Glu Leu Gln Tyr Arg Asn Arg Gly Asp
                 155                 160                 165

 Pro Trp Ala Val Ser Pro Arg Arg Lys Leu Ile Ser Val Asp Ser
                 170                 175                 180

 Arg Ser Val Ser Leu Leu Pro Leu Glu Phe Arg Lys Asp Ser Ser
                 185                 190                 195

 Tyr Glu Leu Gln Val Arg Ala Gly Pro Met Pro Gly Ser Ser Tyr
                 200                 205                 210

 Gln Gly Thr Trp Ser Glu Trp Ser Asp Pro Val Ile Phe Gln Thr
                 215                 220                 225

 Gln Ser Glu Glu Leu Lys Glu Gly Trp Asn Pro His Leu Leu Leu
                 230                 235                 240

 Leu Leu Leu Leu Val Ile Val Phe Ile Pro Ala Phe Trp Ser Leu
                 245                 250                 255

 Lys Thr His Pro Leu Trp Arg Leu Trp Lys Lys Ile Trp Ala Val
                 260                 265                 270

 Pro Ser Pro Glu Arg Phe Phe Met Pro Leu Tyr Lys Gly Cys Ser
                 275                 280                 285

 Gly Asp Phe Lys Lys Trp Val Gly Ala Pro Phe Thr Gly Ser Ser
                 290                 295                 300

 Leu Glu Leu Gly Pro Trp Ser Pro Glu Val Pro Ser Thr Leu Glu
                 305                 310                 315

 Val Tyr Ser Cys His Pro Pro Arg Ser Pro Ala Lys Arg Leu Gln
                 320                 325                 330

 Leu Thr Glu Leu Gln Glu Pro Ala Glu Leu Val Glu Ser Asp Gly
                 335                 340                 345

 Val Pro Lys Pro Ser Phe Trp Pro Thr Ala Gln Asn Ser Gly Gly
                 350                 355                 360

 Ser Ala Tyr Ser Glu Glu Arg Asp Arg Pro Tyr Gly Leu Val Ser
                 365                 370                 375

 Ile Asp Thr Val Thr Val Leu Asp Ala Glu Gly Pro Cys Thr Trp
                 380                 385                 390

 Pro Cys Ser Cys Glu Asp Asp Gly Tyr Pro Ala Leu Asp Leu Asp
                 395                 400                 405

 Ala Gly Leu Glu Pro Ser Pro Gly Leu Glu Asp Pro Leu Leu Asp
                 410                 415                 420

 Ala Gly Thr Thr Val Leu Ser Cys Gly Cys Val Ser Ala Gly Ser
                 425                 430                 435

 Pro Gly Leu Gly Gly Pro Leu Gly Ser Leu Leu Asp Arg Leu Lys
                 440                 445                 450

 Pro Pro Leu Ala Asp Gly Glu Asp Trp Ala Gly Gly Leu Pro Trp
                 455                 460                 465

 Gly Gly Arg Ser Pro Gly Gly Val Ser Glu Ser Glu Ala Gly Ser
                 470                 475                 480

 Pro Leu Ala Gly Leu Asp Met Asp Thr Phe Asp Ser Gly Phe Val
                 485                 490                 495

 Gly Ser Asp Cys Ser Ser Pro Val Glu Cys Asp Phe Thr Ser Pro
                 500                 505                 510

 Gly Asp Glu Gly Pro Pro Arg Ser Tyr Leu Arg Gln Trp Val Val
                 515                 520                 525

 Ile Pro Pro Pro Leu Ser Ser Pro Gly Pro Gln Ala Ser
                 530                 535

<210> 5896
<211> 1853
<212> DNA
<213> Homo sapien

<400> 5896
 gcgagatccc taccgcagta gccgcctctg ccgccgcgga gcttcccgaa 50

 cctctcagcc gcccggagcc gctcccggag cccggccgta gaggctgcaa 100

 tcgcagccgg gagcccgcag cccgcgcccc gagcccgccg ccgcccttcg 150

 agggcgcccc aggccgcgcc atggtgaagg tgacgttcaa ctccgctctg 200

 gcccagaagg aggccaagaa ggacgagccc aagagcggcg aggaggcgct 250

 catcatcccc cccgacgccg tcgcggtgga ctgcaaggac ccagatgatg 300

 tggtaccagt tggccaaaga agagcctggt gttggtgcat gtgctttgga 350

 ctagcattta tgcttgcagg tgttattcta ggaggagcat acttgtacaa 400

 atattttgca cttcaaccag atgacgtgta ctactgtgga ataaagtaca 450

 tcaaagatga tgtcatctta aatgagccct ctgcagatgc cccagctgct 500

 ctctaccaga caattgaaga aaatattaaa atctttgaag aagaagaagt 550

 tgaatttatc agtgtgcctg tcccagagtt tgcagatagt gatcctgcca 600

 acattgttca tgactttaac aagaaactta cagcctattt agatcttaac 650

 ctggataagt gctatgtgat ccctctgaac acttccattg ttatgccacc 700

 cagaaaccta ctggagttac ttattaacat caaggctgga acctatttgc 750

 ctcagtccta tctgattcat gagcacatgg ttattactga tcgcattgaa 800

 aacattgatc acctgggttt ctttatttat cgactgtgtc atgacaagga 850

 aacttacaaa ctgcaacgca gagaaactat taaaggtatt cagaaacgtg 900

 aagccagcaa ttgtttcgca attcggcatt ttgaaaacaa atttgccgtg 950

 gaaactttaa tttgttttaa tttgttcttg aacagtcaag aaaaacatta 1000

 ttgaggaaaa ttaatatcac agcataaccc caccctttac attttgtgca 1050

 gtgattattt tttaaagtct tctttcatgt aagtagcaaa cagggcttta 1100

 ctatcttttc atctcattaa ttcaattaaa accattacct taaaattttt 1150

 ttctttcgaa gtgtggtgtc ttttatattt gaattagtaa ctgtatgaag 1200

 tcatagataa tagtacatgt caccttaggt agtaggaaga attacaattt 1250

 ctttaaatca tttatctgga tttttatgtt ttattagcat tttcaagaag 1300

 acggattatc tagagaataa tcatatatat gcatacgtaa aaatggacca 1350

 cagtgactta tttgtagttg ttagttgccc tgctacctag tttgttagtg 1400

 catttgagca cacattttaa ttttcctcta attaaaatgt gcagtatttt 1450

 cagtgtcaaa tatatttaac tatttagaga atgatttcca cctttatgtt 1500

 ttaatatcct aggcatctgc tgtaataata ttttagaaaa tgtttggaat 1550

 ttaagaaata acttgtgtta ctaatttgta taacccatat ctgtgcaatg 1600

 gaatataaat atcacaaagt tgtttaacta gactgcgtgt tgtttttccc 1650

 gtataataaa accaaagaat agtttggttc ttcaaatctt aagagaatcc 1700

 acataaaaga agaaactatt ttttaaaaat tcacttctat atatacaatg 1750

 agtaaaatca cagatttttt ctttaaataa aaataagtca ttttaataac 1800

 taaaccagat tctttgtgga tactattaaa gtaacattta agcctcaacc 1850

 ttg 1853

<210> 5897
<211> 277
<212> PRT
<213> Homo sapien

<400> 5897
 Met Val Lys Val Thr Phe Asn Ser Ala Leu Ala Gln Lys Glu Ala
   1               5                  10                  15

 Lys Lys Asp Glu Pro Lys Ser Gly Glu Glu Ala Leu Ile Ile Pro
                  20                  25                  30

 Pro Asp Ala Val Ala Val Asp Cys Lys Asp Pro Asp Asp Val Val
                  35                  40                  45

 Pro Val Gly Gln Arg Arg Ala Trp Cys Trp Cys Met Cys Phe Gly
                  50                  55                  60

 Leu Ala Phe Met Leu Ala Gly Val Ile Leu Gly Gly Ala Tyr Leu
                  65                  70                  75

 Tyr Lys Tyr Phe Ala Leu Gln Pro Asp Asp Val Tyr Tyr Cys Gly
                  80                  85                  90

 Ile Lys Tyr Ile Lys Asp Asp Val Ile Leu Asn Glu Pro Ser Ala
                  95                 100                 105

 Asp Ala Pro Ala Ala Leu Tyr Gln Thr Ile Glu Glu Asn Ile Lys
                 110                 115                 120

 Ile Phe Glu Glu Glu Glu Val Glu Phe Ile Ser Val Pro Val Pro
                 125                 130                 135

 Glu Phe Ala Asp Ser Asp Pro Ala Asn Ile Val His Asp Phe Asn
                 140                 145                 150

 Lys Lys Leu Thr Ala Tyr Leu Asp Leu Asn Leu Asp Lys Cys Tyr
                 155                 160                 165

 Val Ile Pro Leu Asn Thr Ser Ile Val Met Pro Pro Arg Asn Leu
                 170                 175                 180

 Leu Glu Leu Leu Ile Asn Ile Lys Ala Gly Thr Tyr Leu Pro Gln
                 185                 190                 195

 Ser Tyr Leu Ile His Glu His Met Val Ile Thr Asp Arg Ile Glu
                 200                 205                 210

 Asn Ile Asp His Leu Gly Phe Phe Ile Tyr Arg Leu Cys His Asp
                 215                 220                 225

 Lys Glu Thr Tyr Lys Leu Gln Arg Arg Glu Thr Ile Lys Gly Ile
                 230                 235                 240

 Gln Lys Arg Glu Ala Ser Asn Cys Phe Ala Ile Arg His Phe Glu
                 245                 250                 255

 Asn Lys Phe Ala Val Glu Thr Leu Ile Cys Phe Asn Leu Phe Leu
                 260                 265                 270

 Asn Ser Gln Glu Lys His Tyr
                 275

<210> 5898
<211> 810
<212> DNA
<213> Homo sapien

<400> 5898
 gctggagccg ggccggggcg atgtggagcg cgggccgcgg cggggctgcc 50

 tggccggtgc tgttggggct gctgctggcg ctgttagtgc cgggcggtgg 100

 tgccgccaag accggtgcgg agctcgtgac ctgcgggtcg gtgctgaagc 150

 tgctcaatac gcaccaccgc gtgcggctgc actcgcacga catcaaatac 200

 ggatccggca gcggccagca atcggtgacc ggcgtagagg cgtcggacga 250

 cgcgaatagc tactggcgga tccgcggcgg ctcggagggc gggtgcccgt 300

 gcgggtcccc ggtgcgctgc gggcaggcgg tgaggctcac gcatgtgctt 350

 acgggcaaga acctgcacac gcaccacttc ccgtcgccgc tgtccaacaa 400

 ccaggaggtg agtgcctttg gggaagacgg cgagggcgac gacctggacc 450

 tatggacagt gcgctgctct ggacagcact gggagcgtga ggctgctgtg 500

 cgcttacagc atgtgggcac ctctgtgttc ctgtcagtca cgggtgagca 550

 gtatggaagc cccatccgtg ggcagcatga ggtccacggc atgcccagtg 600

 ccaacacgca caatacgtgg aaggccatgg aaggcatctt catcaagcct 650

 agtgtggagc cctctgcagg tcacgatgaa ctctgagtgt gtggatggat 700

 gggtggatgg agggtggcag gtggggcgtc tgcagggcca ctcttggcag 750

 agactttggg tttgtagggg tcctcaagtg cctttgtgat taaagaatgt 800

 tggtctatga 810

<210> 5899
<211> 221
<212> PRT
<213> Homo sapien

<400> 5899
 Met Trp Ser Ala Gly Arg Gly Gly Ala Ala Trp Pro Val Leu Leu
   1               5                  10                  15

 Gly Leu Leu Leu Ala Leu Leu Val Pro Gly Gly Gly Ala Ala Lys
                  20                  25                  30

 Thr Gly Ala Glu Leu Val Thr Cys Gly Ser Val Leu Lys Leu Leu
                  35                  40                  45

 Asn Thr His His Arg Val Arg Leu His Ser His Asp Ile Lys Tyr
                  50                  55                  60

 Gly Ser Gly Ser Gly Gln Gln Ser Val Thr Gly Val Glu Ala Ser
                  65                  70                  75

 Asp Asp Ala Asn Ser Tyr Trp Arg Ile Arg Gly Gly Ser Glu Gly
                  80                  85                  90

 Gly Cys Pro Cys Gly Ser Pro Val Arg Cys Gly Gln Ala Val Arg
                  95                 100                 105

 Leu Thr His Val Leu Thr Gly Lys Asn Leu His Thr His His Phe
                 110                 115                 120

 Pro Ser Pro Leu Ser Asn Asn Gln Glu Val Ser Ala Phe Gly Glu
                 125                 130                 135

 Asp Gly Glu Gly Asp Asp Leu Asp Leu Trp Thr Val Arg Cys Ser
                 140                 145                 150

 Gly Gln His Trp Glu Arg Glu Ala Ala Val Arg Leu Gln His Val
                 155                 160                 165

 Gly Thr Ser Val Phe Leu Ser Val Thr Gly Glu Gln Tyr Gly Ser
                 170                 175                 180

 Pro Ile Arg Gly Gln His Glu Val His Gly Met Pro Ser Ala Asn
                 185                 190                 195

 Thr His Asn Thr Trp Lys Ala Met Glu Gly Ile Phe Ile Lys Pro
                 200                 205                 210

 Ser Val Glu Pro Ser Ala Gly His Asp Glu Leu
                 215                 220

<210> 5900
<211> 3325
<212> DNA
<213> Homo sapien

<400> 5900
 cttacggcag tctcgcggga tttccccctc tcgcgggaat tatttgaacg 50

 ttcgagcggt aaatactccc tggggctgtc atagaagact cctcggagag 100

 cgctgcctct gggttggcgg gctggcaggc tgtagccgag cgcgggcagg 150

 actcgtcccg gcagggttcc agagccatgg gagcggaaag gaggctgctg 200

 tcgattaagg aggcctttcg gctggcgcag cagccgcacc agaaccaggc 250

 gaagctggtg gtggcgctga gccgcaccta ccgcacgatg gatgataaga 300

 cagtttttca tgaggagttc attcattacc ttaaatatgt tatggtggtc 350

 tataaacgtg aaccagctgt ggagagggta atagaatttg cagcaaagtt 400

 tgttacctca tttcaccaat cagatatgga agatgatgag gaagaggaag 450

 atggtggcct tttaaattat ttgtttactt ttctcttaaa gtctcatgaa 500

 gcaaacagca atgcagtgag atttagagtg tgcctgctca taaacaagct 550

 tttgggaagt atgccagaaa atgctcagat tgatgatgat gtgtttgata 600

 aaattaataa agccatgctt attagattga aagataagat tccaaatgtg 650

 agaatacagg cagttctggc gctttcacga cttcaggatc ccaaggatga 700

 tgaatgccca gtggttaatg catatgctac tttgattgaa aatgattcaa 750

 atccagaagt tagacgggca gtgttatcat gtattgcacc atcagcaaag 800

 actttgccaa aaattgtagg gcgcaccaag gatgtgaaag aggctgtcag 850

 aaagctggct tatcaggttt tagctgaaaa ggttcatatg agagctatgt 900

 ccattgctca gagagtaatg ctccttcaac aaggtcttaa tgacagatca 950

 gatgctgtga aacaagctat gcagaagcat cttcttcaag gctggttacg 1000

 gttctctgaa ggaaatatct tagagttgct ccatcggttg gatgtagaaa 1050

 attcttctga agtggcagtc tctgttctca atgccttgtt ttcaataact 1100

 cctctcagtg aactggtggg actctgtaaa aacaatgatg gcaggaaatt 1150

 gattccagtg gaaacattaa ctcctgaaat tgctttgtat tggtgtgccc 1200

 tttgtgaata tttgaaatca aaaggagatg aaggtgaaga atttttagag 1250

 cagattttgc cagagcctgt agtatatgca gactatttat tgagttacat 1300

 ccagagcatt ccagttgtta atgaagaaca cagaggtgat ttttcctata 1350

 ttggaaattt gatgacaaaa gaattcatag gtcaacaatt gattctaatt 1400

 attaagtctt tggataccag tgaagaagga ggaagaaaaa aactgctggc 1450

 tgttttacag gagattctta ttttacccac aatcccaata tccctggttt 1500

 cttttcttgt tgaaagacta ctccacatca ttatagatga taataagaga 1550

 acacaaattg ttacagaaat tatctcagag attcgggcgc ccattgttac 1600

 tgttggtgtt aataacgatc cagctgatgt aagaaagaaa gaactcaaga 1650

 tggctgaaat aaaagttaag cttatcgaag ccaaagaagc tttggaaaat 1700

 tgcattacct tacaggattt taatcgggca tcagaattaa aagaagaaat 1750

 aaaagcatta gaagatgcca gaataaacct tttgaaagag acagagcaac 1800

 ttgaaattaa agaagtccac atagagaaga atgatgctga aacattgcag 1850

 aaatgtctta ttttatgcta tgaactgttg aagcagatgt ccatttcaac 1900

 aggcttaagt gcaaccatga atggaatcat cgaatctttg attcttcctg 1950

 gaataataag tattcatcct gttgtaagaa acctggctgt tttatgcttg 2000

 ggatgctgtg gactacagaa tcaggatttt gcaaggaaac acttcgtatt 2050

 actattgcag gttttgcaaa ttgatgatgt cacaataaaa ataagtgctt 2100

 taaaggcaat ctttgaccaa ctgatgacgt tcgggattga accatttaaa 2150

 actaaaaaaa tcaaaacact tcattgtgaa ggtacagaaa taaacagtga 2200

 tgatgagcaa gaatcaaaag aagttgaaga gactgctaca gctaagaatg 2250

 ttctgaaact cctttctgat ttcttagata gtgaggtatc tgaacttagg 2300

 actggagctg cagaaggact agccaagctg atgttctctg ggcttttggt 2350

 cagcagcagg attctttctc gtcttatttt gttatggtac aatcctgtga 2400

 ctgaagagga tgttcaactt cgacattgcc taggcgtgtt cttccccgtg 2450

 tttgcttatg caagcaggac taatcaggaa tgctttgaag aagcttttct 2500

 tccaaccctg caaacactgg ccaatgcccc tgcatcttct cctttagctg 2550

 aaattgatat cacaaatgtt gctgagttac ttgtagattt gacaagacca 2600

 agtggattaa atcctcaggc caagacttcc caagattatc aggccttaac 2650

 agtacatgac aatttggcta tgaaaatttg caatgagatc ttaacaagtc 2700

 cgtgctcgcc agaaattcga gtctatacaa aagccttgag ttctttagaa 2750

 ctcagtagcc atcttgcaaa agatcttctg gttctattga atgagattct 2800

 ggagcaagta aaagatagga catgtctgag agctttggag aaaatcaaga 2850

 ttcagttaga aaaaggaaat aaagaatttg gtgaccaagc tgaagcagca 2900

 caggatgcca ccttgactac aactactttc caaaatgaag atgaaaagaa 2950

 taaagaagta tatatgactc cactcagggg tgtaaaagca acccaagcat 3000

 caaagtctac tcagctaaag actaacagag gacagagaaa agtgacagtt 3050

 tcagctagga cgaacaggag gtgtcagact gctgaagccg actctgaaag 3100

 tgatcatgaa gttccagaac cagaatcaga aatgaagatg agactaccaa 3150

 gacgagccaa aaccgcagca ctagaaaaaa gtaaacttaa ccttgcccaa 3200

 tttctcaatg aagatctaag ttaggaaaga cgatggaggt ggaatccttt 3250

 aagattatgt ccagttattt gctttaataa agaagaagtt acccttgtca 3300

 aaatcagaga aaaaaaaaaa aaaaa 3325

<210> 5901
<211> 1015
<212> PRT
<213> Homo sapien

<400> 5901
 Met Gly Ala Glu Arg Arg Leu Leu Ser Ile Lys Glu Ala Phe Arg
   1               5                  10                  15

 Leu Ala Gln Gln Pro His Gln Asn Gln Ala Lys Leu Val Val Ala
                  20                  25                  30

 Leu Ser Arg Thr Tyr Arg Thr Met Asp Asp Lys Thr Val Phe His
                  35                  40                  45

 Glu Glu Phe Ile His Tyr Leu Lys Tyr Val Met Val Val Tyr Lys
                  50                  55                  60

 Arg Glu Pro Ala Val Glu Arg Val Ile Glu Phe Ala Ala Lys Phe
                  65                  70                  75

 Val Thr Ser Phe His Gln Ser Asp Met Glu Asp Asp Glu Glu Glu
                  80                  85                  90

 Glu Asp Gly Gly Leu Leu Asn Tyr Leu Phe Thr Phe Leu Leu Lys
                  95                 100                 105

 Ser His Glu Ala Asn Ser Asn Ala Val Arg Phe Arg Val Cys Leu
                 110                 115                 120

 Leu Ile Asn Lys Leu Leu Gly Ser Met Pro Glu Asn Ala Gln Ile
                 125                 130                 135

 Asp Asp Asp Val Phe Asp Lys Ile Asn Lys Ala Met Leu Ile Arg
                 140                 145                 150

 Leu Lys Asp Lys Ile Pro Asn Val Arg Ile Gln Ala Val Leu Ala
                 155                 160                 165

 Leu Ser Arg Leu Gln Asp Pro Lys Asp Asp Glu Cys Pro Val Val
                 170                 175                 180

 Asn Ala Tyr Ala Thr Leu Ile Glu Asn Asp Ser Asn Pro Glu Val
                 185                 190                 195

 Arg Arg Ala Val Leu Ser Cys Ile Ala Pro Ser Ala Lys Thr Leu
                 200                 205                 210

 Pro Lys Ile Val Gly Arg Thr Lys Asp Val Lys Glu Ala Val Arg
                 215                 220                 225

 Lys Leu Ala Tyr Gln Val Leu Ala Glu Lys Val His Met Arg Ala
                 230                 235                 240

 Met Ser Ile Ala Gln Arg Val Met Leu Leu Gln Gln Gly Leu Asn
                 245                 250                 255

 Asp Arg Ser Asp Ala Val Lys Gln Ala Met Gln Lys His Leu Leu
                 260                 265                 270

 Gln Gly Trp Leu Arg Phe Ser Glu Gly Asn Ile Leu Glu Leu Leu
                 275                 280                 285

 His Arg Leu Asp Val Glu Asn Ser Ser Glu Val Ala Val Ser Val
                 290                 295                 300

 Leu Asn Ala Leu Phe Ser Ile Thr Pro Leu Ser Glu Leu Val Gly
                 305                 310                 315

 Leu Cys Lys Asn Asn Asp Gly Arg Lys Leu Ile Pro Val Glu Thr
                 320                 325                 330

 Leu Thr Pro Glu Ile Ala Leu Tyr Trp Cys Ala Leu Cys Glu Tyr
                 335                 340                 345

 Leu Lys Ser Lys Gly Asp Glu Gly Glu Glu Phe Leu Glu Gln Ile
                 350                 355                 360

 Leu Pro Glu Pro Val Val Tyr Ala Asp Tyr Leu Leu Ser Tyr Ile
                 365                 370                 375

 Gln Ser Ile Pro Val Val Asn Glu Glu His Arg Gly Asp Phe Ser
                 380                 385                 390

 Tyr Ile Gly Asn Leu Met Thr Lys Glu Phe Ile Gly Gln Gln Leu
                 395                 400                 405

 Ile Leu Ile Ile Lys Ser Leu Asp Thr Ser Glu Glu Gly Gly Arg
                 410                 415                 420

 Lys Lys Leu Leu Ala Val Leu Gln Glu Ile Leu Ile Leu Pro Thr
                 425                 430                 435

 Ile Pro Ile Ser Leu Val Ser Phe Leu Val Glu Arg Leu Leu His
                 440                 445                 450

 Ile Ile Ile Asp Asp Asn Lys Arg Thr Gln Ile Val Thr Glu Ile
                 455                 460                 465

 Ile Ser Glu Ile Arg Ala Pro Ile Val Thr Val Gly Val Asn Asn
                 470                 475                 480

 Asp Pro Ala Asp Val Arg Lys Lys Glu Leu Lys Met Ala Glu Ile
                 485                 490                 495

 Lys Val Lys Leu Ile Glu Ala Lys Glu Ala Leu Glu Asn Cys Ile
                 500                 505                 510

 Thr Leu Gln Asp Phe Asn Arg Ala Ser Glu Leu Lys Glu Glu Ile
                 515                 520                 525

 Lys Ala Leu Glu Asp Ala Arg Ile Asn Leu Leu Lys Glu Thr Glu
                 530                 535                 540

 Gln Leu Glu Ile Lys Glu Val His Ile Glu Lys Asn Asp Ala Glu
                 545                 550                 555

 Thr Leu Gln Lys Cys Leu Ile Leu Cys Tyr Glu Leu Leu Lys Gln
                 560                 565                 570

 Met Ser Ile Ser Thr Gly Leu Ser Ala Thr Met Asn Gly Ile Ile
                 575                 580                 585

 Glu Ser Leu Ile Leu Pro Gly Ile Ile Ser Ile His Pro Val Val
                 590                 595                 600

 Arg Asn Leu Ala Val Leu Cys Leu Gly Cys Cys Gly Leu Gln Asn
                 605                 610                 615

 Gln Asp Phe Ala Arg Lys His Phe Val Leu Leu Leu Gln Val Leu
                 620                 625                 630

 Gln Ile Asp Asp Val Thr Ile Lys Ile Ser Ala Leu Lys Ala Ile
                 635                 640                 645

 Phe Asp Gln Leu Met Thr Phe Gly Ile Glu Pro Phe Lys Thr Lys
                 650                 655                 660

 Lys Ile Lys Thr Leu His Cys Glu Gly Thr Glu Ile Asn Ser Asp
                 665                 670                 675

 Asp Glu Gln Glu Ser Lys Glu Val Glu Glu Thr Ala Thr Ala Lys
                 680                 685                 690

 Asn Val Leu Lys Leu Leu Ser Asp Phe Leu Asp Ser Glu Val Ser
                 695                 700                 705

 Glu Leu Arg Thr Gly Ala Ala Glu Gly Leu Ala Lys Leu Met Phe
                 710                 715                 720

 Ser Gly Leu Leu Val Ser Ser Arg Ile Leu Ser Arg Leu Ile Leu
                 725                 730                 735

 Leu Trp Tyr Asn Pro Val Thr Glu Glu Asp Val Gln Leu Arg His
                 740                 745                 750

 Cys Leu Gly Val Phe Phe Pro Val Phe Ala Tyr Ala Ser Arg Thr
                 755                 760                 765

 Asn Gln Glu Cys Phe Glu Glu Ala Phe Leu Pro Thr Leu Gln Thr
                 770                 775                 780

 Leu Ala Asn Ala Pro Ala Ser Ser Pro Leu Ala Glu Ile Asp Ile
                 785                 790                 795

 Thr Asn Val Ala Glu Leu Leu Val Asp Leu Thr Arg Pro Ser Gly
                 800                 805                 810

 Leu Asn Pro Gln Ala Lys Thr Ser Gln Asp Tyr Gln Ala Leu Thr
                 815                 820                 825

 Val His Asp Asn Leu Ala Met Lys Ile Cys Asn Glu Ile Leu Thr
                 830                 835                 840

 Ser Pro Cys Ser Pro Glu Ile Arg Val Tyr Thr Lys Ala Leu Ser
                 845                 850                 855

 Ser Leu Glu Leu Ser Ser His Leu Ala Lys Asp Leu Leu Val Leu
                 860                 865                 870

 Leu Asn Glu Ile Leu Glu Gln Val Lys Asp Arg Thr Cys Leu Arg
                 875                 880                 885

 Ala Leu Glu Lys Ile Lys Ile Gln Leu Glu Lys Gly Asn Lys Glu
                 890                 895                 900

 Phe Gly Asp Gln Ala Glu Ala Ala Gln Asp Ala Thr Leu Thr Thr
                 905                 910                 915

 Thr Thr Phe Gln Asn Glu Asp Glu Lys Asn Lys Glu Val Tyr Met
                 920                 925                 930

 Thr Pro Leu Arg Gly Val Lys Ala Thr Gln Ala Ser Lys Ser Thr
                 935                 940                 945

 Gln Leu Lys Thr Asn Arg Gly Gln Arg Lys Val Thr Val Ser Ala
                 950                 955                 960

 Arg Thr Asn Arg Arg Cys Gln Thr Ala Glu Ala Asp Ser Glu Ser
                 965                 970                 975

 Asp His Glu Val Pro Glu Pro Glu Ser Glu Met Lys Met Arg Leu
                 980                 985                 990

 Pro Arg Arg Ala Lys Thr Ala Ala Leu Glu Lys Ser Lys Leu Asn
                 995                1000                1005

 Leu Ala Gln Phe Leu Asn Glu Asp Leu Ser
                1010                1015

<210> 5902
<211> 1700
<212> DNA
<213> Homo sapien

<400> 5902
 cggaattggt gggttcttgg tctcactgag ttctagaatg aagctgcaga 50

 ccctcgcagt gagtgttaca gctcttaagg ctctctgact gccacccctg 100

 cctgcctgcc cggccctgca caacatgcag ccctccggcc tcgagggtcc 150

 cggcacgttt ggtcggtggc ctctgctgag tctgctgctc ctgctgctgc 200

 tgctccagcc tgtaacctgt gcctacacca cgccaggccc ccccagagcc 250

 ctcaccacgc tgggcgcccc cagagcccac accatgccgg gcacctacgc 300

 tccctcgacc acactcagta gtcccagcac ccagggcctg caagagcagg 350

 cacgggccct gatgcgggac ttcccgctcg tggacggcca caacgacctg 400

 cccctggtcc taaggcaggt ttaccagaaa gggctacagg atgttaacct 450

 gcgcaatttc agctacggcc agaccagcct ggacaggctt agagatggcc 500

 tcgtgggcgc ccagttctgg tcagcctatg tgccatgcca gacccaggac 550

 cgggatgccc tgcgcctcac cctggagcag attgacctca tacgccgcat 600

 gtgtgcctcc tattctgagc tggagcttgt gacctcggct aaagctctga 650

 acgacactca gaaattggcc tgcctcatcg gtgtagaggg tggccactcg 700

 ctggacaata gcctctccat cttacgtacc ttctacatgc tgggagtgcg 750

 ctacctgacg ctcacccaca cctgcaacac accctgggca gagagctccg 800

 ctaagggcgt ccactccttc tacaacaaca tcagcgggct gactgacttt 850

 ggtgagaagg tggtggcaga aatgaaccgc ctgggcatga tggtagactt 900

 atcccatgtc tcagatgctg tggcacggcg ggccctggaa gtgtcacagg 950

 cacctgtgat cttctcccac tcggctgccc ggggtgtgtg caacagtgct 1000

 cggaatgttc ctgatgacat cctgcagctt ctgaagaaga acggtggcgt 1050

 cgtgatggtg tctttgtcca tgggagtaat acagtgcaac ccatcagcca 1100

 atgtgtccac tgtggcagat cacttcgacc acatcaaggc tgtcattgga 1150

 tccaagttca tcgggattgg tggagattat gatggggccg gcaaattccc 1200

 tcaggggctg gaagacgtgt ccacataccc ggtcctgata gaggagttgc 1250

 tgagtcgtgg ctggagtgag gaagagcttc agggtgtcct tcgtggaaac 1300

 ctgctgcggg tcttcagaca agtggaaaag gtacaggaag aaaacaaatg 1350

 gcaaagcccc ttggaggaca agttcccgga tgagcagctg agcagttcct 1400

 gccactccga cctctcacgt ctgcgtcaga gacagagtct gacttcaggc 1450

 caggaactca ctgagattcc catacactgg acagccaagt taccagccaa 1500

 gtggtcagtc tcagagtcct ccccccacat ggccccagtc cttgcagttg 1550

 tggccacctt cccagtcctt attctgtggc tctgatgacc cagttagtcc 1600

 tgccagatgt cactgtagca agccacagac accccacaaa gttcccctgt 1650

 tgtgcaggca caaatatttc ttgaaataaa tgttttggac atagaaaaaa 1700

<210> 5903
<211> 486
<212> PRT
<213> Homo sapien

<400> 5903
 Met Gln Pro Ser Gly Leu Glu Gly Pro Gly Thr Phe Gly Arg Trp
   1               5                  10                  15

 Pro Leu Leu Ser Leu Leu Leu Leu Leu Leu Leu Leu Gln Pro Val
                  20                  25                  30

 Thr Cys Ala Tyr Thr Thr Pro Gly Pro Pro Arg Ala Leu Thr Thr
                  35                  40                  45

 Leu Gly Ala Pro Arg Ala His Thr Met Pro Gly Thr Tyr Ala Pro
                  50                  55                  60

 Ser Thr Thr Leu Ser Ser Pro Ser Thr Gln Gly Leu Gln Glu Gln
                  65                  70                  75

 Ala Arg Ala Leu Met Arg Asp Phe Pro Leu Val Asp Gly His Asn
                  80                  85                  90

 Asp Leu Pro Leu Val Leu Arg Gln Val Tyr Gln Lys Gly Leu Gln
                  95                 100                 105

 Asp Val Asn Leu Arg Asn Phe Ser Tyr Gly Gln Thr Ser Leu Asp
                 110                 115                 120

 Arg Leu Arg Asp Gly Leu Val Gly Ala Gln Phe Trp Ser Ala Tyr
                 125                 130                 135

 Val Pro Cys Gln Thr Gln Asp Arg Asp Ala Leu Arg Leu Thr Leu
                 140                 145                 150

 Glu Gln Ile Asp Leu Ile Arg Arg Met Cys Ala Ser Tyr Ser Glu
                 155                 160                 165

 Leu Glu Leu Val Thr Ser Ala Lys Ala Leu Asn Asp Thr Gln Lys
                 170                 175                 180

 Leu Ala Cys Leu Ile Gly Val Glu Gly Gly His Ser Leu Asp Asn
                 185                 190                 195

 Ser Leu Ser Ile Leu Arg Thr Phe Tyr Met Leu Gly Val Arg Tyr
                 200                 205                 210

 Leu Thr Leu Thr His Thr Cys Asn Thr Pro Trp Ala Glu Ser Ser
                 215                 220                 225

 Ala Lys Gly Val His Ser Phe Tyr Asn Asn Ile Ser Gly Leu Thr
                 230                 235                 240

 Asp Phe Gly Glu Lys Val Val Ala Glu Met Asn Arg Leu Gly Met
                 245                 250                 255

 Met Val Asp Leu Ser His Val Ser Asp Ala Val Ala Arg Arg Ala
                 260                 265                 270

 Leu Glu Val Ser Gln Ala Pro Val Ile Phe Ser His Ser Ala Ala
                 275                 280                 285

 Arg Gly Val Cys Asn Ser Ala Arg Asn Val Pro Asp Asp Ile Leu
                 290                 295                 300

 Gln Leu Leu Lys Lys Asn Gly Gly Val Val Met Val Ser Leu Ser
                 305                 310                 315

 Met Gly Val Ile Gln Cys Asn Pro Ser Ala Asn Val Ser Thr Val
                 320                 325                 330

 Ala Asp His Phe Asp His Ile Lys Ala Val Ile Gly Ser Lys Phe
                 335                 340                 345

 Ile Gly Ile Gly Gly Asp Tyr Asp Gly Ala Gly Lys Phe Pro Gln
                 350                 355                 360

 Gly Leu Glu Asp Val Ser Thr Tyr Pro Val Leu Ile Glu Glu Leu
                 365                 370                 375

 Leu Ser Arg Gly Trp Ser Glu Glu Glu Leu Gln Gly Val Leu Arg
                 380                 385                 390

 Gly Asn Leu Leu Arg Val Phe Arg Gln Val Glu Lys Val Gln Glu
                 395                 400                 405

 Glu Asn Lys Trp Gln Ser Pro Leu Glu Asp Lys Phe Pro Asp Glu
                 410                 415                 420

 Gln Leu Ser Ser Ser Cys His Ser Asp Leu Ser Arg Leu Arg Gln
                 425                 430                 435

 Arg Gln Ser Leu Thr Ser Gly Gln Glu Leu Thr Glu Ile Pro Ile
                 440                 445                 450

 His Trp Thr Ala Lys Leu Pro Ala Lys Trp Ser Val Ser Glu Ser
                 455                 460                 465

 Ser Pro His Met Ala Pro Val Leu Ala Val Val Ala Thr Phe Pro
                 470                 475                 480

 Val Leu Ile Leu Trp Leu
                 485

<210> 5904
<211> 3257
<212> DNA
<213> Homo sapien

<400> 5904
 ggcatgatgg gcacctggag ggccgcactc ccgttccagc caggctgagc 50

 cttctgtccc ctgcctctgg ggcctgggaa ccccccttct tctttctcct 100

 gaatggcacc cccgccctag aatccagaca ccgagtttcc cactgtggct 150

 ggttcaaggg tatgtgagag ctccctggtg acagtctgtg gctgagcatg 200

 gccctcccag ccctgggcct ggacccctgg agcctcctgg gccttttcct 250

 cttccaactg cttcagctgc tgctgccgac gacgaccgcg gggggaggcg 300

 ggcaggggcc catgcccagg gtcagatact atgcagggga tgaacgtagg 350

 gcacttagct tcttccacca gaagggcctc caggattttg acactctgct 400

 cctgagtggt gatggaaata ctctctacgt gggggctcga gaagccattc 450

 tggccttgga tatccaggat ccaggggtcc ccaggctaaa gaacatgata 500

 ccgtggccag ccagtgacag aaaaaagagt gaatgtgcct ttaagaagaa 550

 gagcaatgag acacagtgtt tcaacttcat ccgtgtcctg gtttcttaca 600

 atgtcaccca tctctacacc tgcggcacct tcgccttcag ccctgcttgt 650

 accttcattg aacttcaaga ttcctacctg ttgcccatct cggaggacaa 700

 ggtcatggag ggaaaaggcc aaagcccctt tgaccccgct cacaagcata 750

 cggctgtctt ggtggatggg atgctctatt ctggtactat gaacaacttc 800

 ctgggcagtg agcccatcct gatgcgcaca ctgggatccc agcctgtcct 850

 caagaccgac aacttcctcc gctggctgca tcatgacgcc tcctttgtgg 900

 cagccatccc ttcgacccag gtcgtctact tcttcttcga ggagacagcc 950

 agcgagtttg acttctttga gaggctccac acatcgcggg tggctagagt 1000

 ctgcaagaat gacgtgggcg gcgaaaagct gctgcagaag aagtggacca 1050

 ccttcctgaa ggcccagctg ctctgcaccc agccggggca gctgcccttc 1100

 aacgtcatcc gccacgcggt cctgctcccc gccgattctc ccacagctcc 1150

 ccacatctac gcagtcttca cctcccagtg gcaggttggc gggaccagga 1200

 gctctgcggt ttgtgccttc tctctcttgg acattgaacg tgtctttaag 1250

 gggaaataca aagagttgaa caaagaaact tcacgctgga ctacttatag 1300

 gggccctgag accaaccccc ggccaggcag ttgctcagtg ggcccctcct 1350

 ctgataaggc cctgaccttc atgaaggacc atttcctgat ggatgagcaa 1400

 gtggtgggga cgcccctgct ggtgaaatct ggcgtggagt atacacggct 1450

 tgcagtggag acagcccagg gccttgatgg gcacagccat cttgtcatgt 1500

 acctgggaac caccacaggg tcgctccaca aggctgtggt aagtggggac 1550

 agcagtgctc atctggtgga agagattcag ctgttccctg accctgaacc 1600

 tgttcgcaac ctgcagctgg cccccaccca gggtgcagtg tttgtaggct 1650

 tctcaggagg tgtctggagg gtgccccgag ccaactgtag tgtctatgag 1700

 agctgtgtgg actgtgtcct tgcccgggac ccccactgtg cctgggaccc 1750

 tgagtcccga acctgttgcc tcctgtctgc ccccaacctg aactcctgga 1800

 agcaggacat ggagcggggg aacccagagt gggcatgtgc cagtggcccc 1850

 atgagcagga gccttcggcc tcagagccgc ccgcaaatca ttaaagaagt 1900

 cctggctgtc cctaactcca tcctggagct cccctgcccc cacctgtcag 1950

 ccttggcctc ttattattgg agtcatggcc cagcagcagt cccagaagcc 2000

 tcttccactg tctacaatgg ctccctcttg ctgatagtgc aggatggagt 2050

 tgggggtctc taccagtgct gggcaactga gaatggcttt tcataccctg 2100

 tgatctccta ctgggtggac agccaggacc agaccctggc cctggatcct 2150

 gaactggcag gcatcccccg ggagcatgtg aaggtcccgt tgaccagggt 2200

 cagtggtggg gccgccctgg ctgcccagca gtcctactgg ccccactttg 2250

 tcactgtcac tgtcctcttt gccttagtgc tttcaggagc cctcatcatc 2300

 ctcgtggcct ccccattgag agcactccgg gctcggggca aggttcaggg 2350

 ctgtgagacc ctgcgccctg gggagaaggc cccgttaagc agagagcaac 2400

 acctccagtc tcccaaggaa tgcaggacct ctgccagtga tgtggacgct 2450

 gacaacaact gcctaggcac tgaggtagct taaactctag gcacaggccg 2500

 gggctgcggt gcaggcacct ggccatgctg gctgggcggc ccaagcacag 2550

 ccctgactag gatgacagca gcacaaaaga ccacctttct cccctgagag 2600

 gagcttctgc tactctgcat cactgatgac actcagcagg gtgatgcaca 2650

 gcagtctgcc tcccctatgg gactcccttc taccaagcac atgagctctc 2700

 taacagggtg ggggctaccc ccagacctgc tcctacactg atattgaaga 2750

 acctggagag gatccttcag ttctggccat tccagggacc ctccagaaac 2800

 acagtgtttc aagagaccct aaaaaacctg cctgtcccag gaccctatgg 2850

 taatgaacac caaacatcta aacaatcata tgctaacatg ccactcctgg 2900

 aaactccact ctgaagctgc cgctttggac accaacactc ccttctccca 2950

 gggtcatgca gggatctgct ccctcctgct tcccttacca gtcgtgcacc 3000

 gctgactccc aggaagtctt tcctgaagtc tgaccacctt tcttcttgct 3050

 tcagttgggg cagactctga tcccttctgc cctggcagaa tggcaggggt 3100

 aatctgagcc ttcttcactc ctttacccta gctgacccct tcacctctcc 3150

 ccctcccttt tcctttgttt tgggattcag aaaactgctt gtcagagact 3200

 gtttattttt tattaaaaat ataaggctta aaaaaaaaaa aaaaaaaaaa 3250

 aaaaaaa 3257

<210> 5905
<211> 761
<212> PRT
<213> Homo sapien

<400> 5905
 Met Ala Leu Pro Ala Leu Gly Leu Asp Pro Trp Ser Leu Leu Gly
   1               5                  10                  15

 Leu Phe Leu Phe Gln Leu Leu Gln Leu Leu Leu Pro Thr Thr Thr
                  20                  25                  30

 Ala Gly Gly Gly Gly Gln Gly Pro Met Pro Arg Val Arg Tyr Tyr
                  35                  40                  45

 Ala Gly Asp Glu Arg Arg Ala Leu Ser Phe Phe His Gln Lys Gly
                  50                  55                  60

 Leu Gln Asp Phe Asp Thr Leu Leu Leu Ser Gly Asp Gly Asn Thr
                  65                  70                  75

 Leu Tyr Val Gly Ala Arg Glu Ala Ile Leu Ala Leu Asp Ile Gln
                  80                  85                  90

 Asp Pro Gly Val Pro Arg Leu Lys Asn Met Ile Pro Trp Pro Ala
                  95                 100                 105

 Ser Asp Arg Lys Lys Ser Glu Cys Ala Phe Lys Lys Lys Ser Asn
                 110                 115                 120

 Glu Thr Gln Cys Phe Asn Phe Ile Arg Val Leu Val Ser Tyr Asn
                 125                 130                 135

 Val Thr His Leu Tyr Thr Cys Gly Thr Phe Ala Phe Ser Pro Ala
                 140                 145                 150

 Cys Thr Phe Ile Glu Leu Gln Asp Ser Tyr Leu Leu Pro Ile Ser
                 155                 160                 165

 Glu Asp Lys Val Met Glu Gly Lys Gly Gln Ser Pro Phe Asp Pro
                 170                 175                 180

 Ala His Lys His Thr Ala Val Leu Val Asp Gly Met Leu Tyr Ser
                 185                 190                 195

 Gly Thr Met Asn Asn Phe Leu Gly Ser Glu Pro Ile Leu Met Arg
                 200                 205                 210

 Thr Leu Gly Ser Gln Pro Val Leu Lys Thr Asp Asn Phe Leu Arg
                 215                 220                 225

 Trp Leu His His Asp Ala Ser Phe Val Ala Ala Ile Pro Ser Thr
                 230                 235                 240

 Gln Val Val Tyr Phe Phe Phe Glu Glu Thr Ala Ser Glu Phe Asp
                 245                 250                 255

 Phe Phe Glu Arg Leu His Thr Ser Arg Val Ala Arg Val Cys Lys
                 260                 265                 270

 Asn Asp Val Gly Gly Glu Lys Leu Leu Gln Lys Lys Trp Thr Thr
                 275                 280                 285

 Phe Leu Lys Ala Gln Leu Leu Cys Thr Gln Pro Gly Gln Leu Pro
                 290                 295                 300

 Phe Asn Val Ile Arg His Ala Val Leu Leu Pro Ala Asp Ser Pro
                 305                 310                 315

 Thr Ala Pro His Ile Tyr Ala Val Phe Thr Ser Gln Trp Gln Val
                 320                 325                 330

 Gly Gly Thr Arg Ser Ser Ala Val Cys Ala Phe Ser Leu Leu Asp
                 335                 340                 345

 Ile Glu Arg Val Phe Lys Gly Lys Tyr Lys Glu Leu Asn Lys Glu
                 350                 355                 360

 Thr Ser Arg Trp Thr Thr Tyr Arg Gly Pro Glu Thr Asn Pro Arg
                 365                 370                 375

 Pro Gly Ser Cys Ser Val Gly Pro Ser Ser Asp Lys Ala Leu Thr
                 380                 385                 390

 Phe Met Lys Asp His Phe Leu Met Asp Glu Gln Val Val Gly Thr
                 395                 400                 405

 Pro Leu Leu Val Lys Ser Gly Val Glu Tyr Thr Arg Leu Ala Val
                 410                 415                 420

 Glu Thr Ala Gln Gly Leu Asp Gly His Ser His Leu Val Met Tyr
                 425                 430                 435

 Leu Gly Thr Thr Thr Gly Ser Leu His Lys Ala Val Val Ser Gly
                 440                 445                 450

 Asp Ser Ser Ala His Leu Val Glu Glu Ile Gln Leu Phe Pro Asp
                 455                 460                 465

 Pro Glu Pro Val Arg Asn Leu Gln Leu Ala Pro Thr Gln Gly Ala
                 470                 475                 480

 Val Phe Val Gly Phe Ser Gly Gly Val Trp Arg Val Pro Arg Ala
                 485                 490                 495

 Asn Cys Ser Val Tyr Glu Ser Cys Val Asp Cys Val Leu Ala Arg
                 500                 505                 510

 Asp Pro His Cys Ala Trp Asp Pro Glu Ser Arg Thr Cys Cys Leu
                 515                 520                 525

 Leu Ser Ala Pro Asn Leu Asn Ser Trp Lys Gln Asp Met Glu Arg
                 530                 535                 540

 Gly Asn Pro Glu Trp Ala Cys Ala Ser Gly Pro Met Ser Arg Ser
                 545                 550                 555

 Leu Arg Pro Gln Ser Arg Pro Gln Ile Ile Lys Glu Val Leu Ala
                 560                 565                 570

 Val Pro Asn Ser Ile Leu Glu Leu Pro Cys Pro His Leu Ser Ala
                 575                 580                 585

 Leu Ala Ser Tyr Tyr Trp Ser His Gly Pro Ala Ala Val Pro Glu
                 590                 595                 600

 Ala Ser Ser Thr Val Tyr Asn Gly Ser Leu Leu Leu Ile Val Gln
                 605                 610                 615

 Asp Gly Val Gly Gly Leu Tyr Gln Cys Trp Ala Thr Glu Asn Gly
                 620                 625                 630

 Phe Ser Tyr Pro Val Ile Ser Tyr Trp Val Asp Ser Gln Asp Gln
                 635                 640                 645

 Thr Leu Ala Leu Asp Pro Glu Leu Ala Gly Ile Pro Arg Glu His
                 650                 655                 660

 Val Lys Val Pro Leu Thr Arg Val Ser Gly Gly Ala Ala Leu Ala
                 665                 670                 675

 Ala Gln Gln Ser Tyr Trp Pro His Phe Val Thr Val Thr Val Leu
                 680                 685                 690

 Phe Ala Leu Val Leu Ser Gly Ala Leu Ile Ile Leu Val Ala Ser
                 695                 700                 705

 Pro Leu Arg Ala Leu Arg Ala Arg Gly Lys Val Gln Gly Cys Glu
                 710                 715                 720

 Thr Leu Arg Pro Gly Glu Lys Ala Pro Leu Ser Arg Glu Gln His
                 725                 730                 735

 Leu Gln Ser Pro Lys Glu Cys Arg Thr Ser Ala Ser Asp Val Asp
                 740                 745                 750

 Ala Asp Asn Asn Cys Leu Gly Thr Glu Val Ala
                 755                 760

<210> 5906
<211> 5113
<212> DNA
<213> Homo sapien

<400> 5906
 agagcttcag tctgagtccc agcgccgaga gcgtgtctga ccggttggac 50

 ccctacagca gcggcggcgg ctcctcgtcg tcgtcggaag agctcgaggc 100

 cgacgcagcc tcggccccga cgggggtccc gggccagccc cgccgtcccg 150

 gccaccccgc gcagcccctc ccgcttcccc agacggcttc ctcgcctcag 200

 ccgcagcaga aagccccgag ggccattgac agcccgggcg gggccgtccg 250

 cgaggggtcg tgcgaggaga aggcagcggc agccgtggcc ccgggaggcc 300

 tccagtctac ccccgggagg agcggggtga ccgcggagaa ggcgcctccg 350

 ccgcccccgc cgcccaccct gtacgtgcag ctccacggag agaccacccg 400

 gcgcttggag gcggaggaga agccattgca gatccaaaat gactacctct 450

 tccaactggg atttggggag ctgtggaggg tgcaggagga aggcatggac 500

 tcggagattg gctgcctcat ccgcttctat gcaggaaaac ctcacagcac 550

 gggtagctct gaacggattc agctctcagg aatgtataat gtccgtaaag 600

 gcaagatgca gttgccagtg aaccgatgga caagacgcca agtcatccta 650

 tgtgggacct gcctgatagt atcatctgtg aaagacagct tgaccggaaa 700

 gatgcatgtt ctgccactaa ttggtggaaa agtagaagaa gtgaaaaagc 750

 accaacactg tttagcattt agctcctctg gaccccaaag ccagacttac 800

 tacatttgct ttgatacttt cacagaatac ttaaggtggc tgcgacaagt 850

 ctccaaggtt gcatcccagc gcattagctc agtggacctc tcgtgttgta 900

 gcctggaaca tctgcctgcc aacctcttct acagccaaga cctcactcat 950

 ctcaatttaa aacaaaactt cctaaggcag aaccctagcc ttccagctgc 1000

 cagggggctt aatgaactgc aaaggttcac caagttgaag agtcttaacc 1050

 tttccaataa tcatttaggg gacttccctc tggcagtctg cagtattcca 1100

 accctggcag agctgaacgt gtcctgcaat gccctgcgat cagtcccggc 1150

 agccgttgga gtgatgcaca acttacagac atttttgttg gatggaaact 1200

 ttctccaatc ccttcctgct gagttggaga acatgaagca gcttagttat 1250

 ctgggtcttt ctttcaatga atttactgac attcccgaag tattggagaa 1300

 attgactgct gtggataaac tttgtatgtc tggaaactgt gtggagaccc 1350

 ttaggctaca ggctttaaga aaaatgcctc acattaaaca tgtggatcta 1400

 aggttgaacg taattaggaa gctgatagca gatgaagtgg actttctaca 1450

 gcatgttact cagcttgacc tacgagacaa taagcttggt gatctagatg 1500

 ctatgatttt caacaacatt gaagttttac actgtgaaag gaatcaactg 1550

 gtcacattag acatctgtgg ctatttccta aaagcgctct atgcctcttc 1600

 taatgaactt gttcaacttg atgtttaccc agttccaaat tatctgtcct 1650

 acatggatgt ttcaaggaac cgcttagaaa atgtgcctga gtgggtatgt 1700

 gaaagccgaa agctagaagt tttggatatt ggccataatc aaatatgtga 1750

 acttcctgcc cgcttatttt gtaatagcag tctccggaaa ctactggcag 1800

 gacacaacca gttggcaagg ctgcctgaaa ggctagaaag aacctcggtg 1850

 gaggtcttgg atgtgcaaca caaccagctc cttgagctcc cacctaacct 1900

 tctgatgaag gctgacagcc tgagattcct gaacgcctct gcgaacaaac 1950

 tggaaagcct tcctccagcc acgctttccg aagagacaaa cagtatctta 2000

 caagagttgt atttgacaaa taacagcctc acagacaaat gtgtgccctt 2050

 gttaacggga cacccccatt tgaagatcct tcacatggcc tataaccgac 2100

 ttcagagttt tccagcaagt aaaatggcga aactggagga acttgaagaa 2150

 attgatctca gtgggaataa gctgaaagcc atcccaacaa cgatcatgaa 2200

 ttgcagccgc atgcacaccg tgattgctca ctccaactgc atcgaggtct 2250

 ttcccgaagt tatgcagctc ccagagatca agtgtgtgga cctgagctgt 2300

 aatgagctaa gtgaagtcac attaccagaa aacctgcctc ccaaactgca 2350

 ggagctagac ctgactggaa acccgcgcct tgtccttgat cacaaaaccc 2400

 tggaactact gaataatatc cgctgtttca agattgatca gccttctaca 2450

 ggagacgctt ccggagcccc agctgtatgg agtcatggtt acactgaagc 2500

 ttcgggggta aaaaacaagt tgtgtgtcgc agccctgtcg gtgaataact 2550

 tctgtgacaa ccgcgaagcc ctgtatggtg tgtttgacgg agaccggaat 2600

 gtggaggtgc cctaccttct ccagtgcact atgagtgaca ttttggctga 2650

 agagctgcaa aaaacaaaaa acgaagaaga atacatggtc aatacattca 2700

 ttgtcatgca aaggaaactt ggaactgctg ggcagaagct tggtggtgcc 2750

 gctgtccttt gtcatatcaa gcatgaccct gtggatccag gaggatcctt 2800

 caccttgacc tctgctaatg tgggcaagtg ccaaacagtt ctctgtcgaa 2850

 atggaaagcc gctgcctctg tccagatctt acatcatgag ctgtgaagaa 2900

 gagctgaaga ggattaaaca gcacaaggcc attatcactg aggatggcaa 2950

 ggtgaacgga gtgactgagt ccacgcgcat cctgggctac accttcctcc 3000

 atcccagtgt ggtgcctcgc ccccacgtgc agtccgtgct cctgactccc 3050

 caggatgagt tcttcatcct aggcagtaag gggttgtggg acagcctgtc 3100

 cgtcgaggag gccgtggaag ccgtgcgcaa cgtgcccgat gccctggctg 3150

 ctgccaagaa gctgtgtacc ctggcccaga gctacggctg ccacgacagc 3200

 atcagcgctg tggtggtgca gctcagtgtc actgaggaca gcttctgctg 3250

 ctgcgagctc agcgccggtg gggctgtgcc accacccagt cctggcatct 3300

 ttcctccctc agtgaacatg gtgatcaagg atcggccctc agatgggctg 3350

 ggcgtgccgt cctccagcag cggcatggct tccgagatta gcagtgagct 3400

 ctccacttct gagatgagca gcgaggtggg gtcaacagcc tccgatgagc 3450

 ccccgcccgg agccctaagc gagaacagcc ctgcctaccc cagtgagcag 3500

 cgctgcatgc tccaccccat ctgtctgtcc aactccttcc agcgccagct 3550

 atccagcgcc acgttctcta gcgccttctc cgacaacggc cttgacagtg 3600

 acgatgagga gcccatcgag ggcgtcttca ccaacggcag ccgggtggag 3650

 gtggaggtgg acatccactg cagccgggcc aaggagaagg agaaacagca 3700

 gcacctgctt caggtgccag cagaggccag tgatgagggc attgtcatca 3750

 gcgccaacga ggatgagcca ggtctgccca ggaaggcaga cttctctgcc 3800

 gttgggacca ttgggcgccg gagggccaat ggctctgttg cgccccagga 3850

 aaggagccac aatgtgatag aggtggctac agacgcacct cttcgaaagc 3900

 ctggaggcta ttttgctgcc ccggctcagc cggatcctga tgatcagttt 3950

 atcatacccc cggagctgga agaggaggtc aaagaaatca tgaagcatca 4000

 ccaggagcaa cagcagcagc agcagccgcc accaccccct cagctccagc 4050

 cgcagctgcc gcggcactac cagctggacc agctgccaga ttattacgac 4100

 acgccactat gacccagccg agctgtttaa caaataaact aaccacaaaa 4150

 gactgagttg caagagtctc ccaggctcac attaaaccag gggttttact 4200

 ccacatcctt cccccagaca ctgttcccaa cctgtcatcg cagctaatct 4250

 gtaggttctc tttctttggg ttattttttt aagtaatcac cactttcttc 4300

 tagtgatgct ttaccaatat gatttacatt tgttaacttc tccccctaac 4350

 atatcagata tgtaaagaca aagaacaaaa ggtttaatat attacagaga 4400

 aacagttaat gataatgtaa tattttttaa aatggctttt tgttgtttgt 4450

 ttggaaggca gggcaggctg ccgttgctaa atgatttaat aatattgtaa 4500

 ttctgtattt ctttgggggg aaaaggcttt tgttttgttt tgttttgttt 4550

 tgttttgttt ttgtcttgaa aataatagac atttgtagaa tatggagact 4600

 aactcctagg agttgcttta ctctgtcagg tgacttaagt cactgggatt 4650

 cactaatttt ctctgagaga acagctgatt gagaatttcc attgtaaata 4700

 gctcagtgtt gtatagtgag gcttacgatg ttttgtagtc ttggcgtaag 4750

 gacacagccc aagtaactga cgtttcccct ccccctcccc tctgaggagc 4800

 ctgcctgcct cacaactcac cctcacttca ctgaatgagg aggctgagca 4850

 gctgcagtgt ttctgtccgg aggaaatgga tcttaggcca ctggacaaga 4900

 acctgcaccc aagggccctg aacccatttt cctcccctgt cccagccttc 4950

 ccactttgac agacactttt aactgtgttc cttactgctg ccacaatcag 5000

 catggttgta tagtgcccca ttaggccatt tacataccca gagttatact 5050

 caagcagaat gcacaaatgg acatgtcata atttttgtta caataaatat 5100

 gaaatttaca agt 5113

<210> 5907
<211> 1369
<212> PRT
<213> Homo sapien

<400> 5907
 Ser Phe Ser Leu Ser Pro Ser Ala Glu Ser Val Ser Asp Arg Leu
   1               5                  10                  15

 Asp Pro Tyr Ser Ser Gly Gly Gly Ser Ser Ser Ser Ser Glu Glu
                  20                  25                  30

 Leu Glu Ala Asp Ala Ala Ser Ala Pro Thr Gly Val Pro Gly Gln
                  35                  40                  45

 Pro Arg Arg Pro Gly His Pro Ala Gln Pro Leu Pro Leu Pro Gln
                  50                  55                  60

 Thr Ala Ser Ser Pro Gln Pro Gln Gln Lys Ala Pro Arg Ala Ile
                  65                  70                  75

 Asp Ser Pro Gly Gly Ala Val Arg Glu Gly Ser Cys Glu Glu Lys
                  80                  85                  90

 Ala Ala Ala Ala Val Ala Pro Gly Gly Leu Gln Ser Thr Pro Gly
                  95                 100                 105

 Arg Ser Gly Val Thr Ala Glu Lys Ala Pro Pro Pro Pro Pro Pro
                 110                 115                 120

 Pro Thr Leu Tyr Val Gln Leu His Gly Glu Thr Thr Arg Arg Leu
                 125                 130                 135

 Glu Ala Glu Glu Lys Pro Leu Gln Ile Gln Asn Asp Tyr Leu Phe
                 140                 145                 150

 Gln Leu Gly Phe Gly Glu Leu Trp Arg Val Gln Glu Glu Gly Met
                 155                 160                 165

 Asp Ser Glu Ile Gly Cys Leu Ile Arg Phe Tyr Ala Gly Lys Pro
                 170                 175                 180

 His Ser Thr Gly Ser Ser Glu Arg Ile Gln Leu Ser Gly Met Tyr
                 185                 190                 195

 Asn Val Arg Lys Gly Lys Met Gln Leu Pro Val Asn Arg Trp Thr
                 200                 205                 210

 Arg Arg Gln Val Ile Leu Cys Gly Thr Cys Leu Ile Val Ser Ser
                 215                 220                 225

 Val Lys Asp Ser Leu Thr Gly Lys Met His Val Leu Pro Leu Ile
                 230                 235                 240

 Gly Gly Lys Val Glu Glu Val Lys Lys His Gln His Cys Leu Ala
                 245                 250                 255

 Phe Ser Ser Ser Gly Pro Gln Ser Gln Thr Tyr Tyr Ile Cys Phe
                 260                 265                 270

 Asp Thr Phe Thr Glu Tyr Leu Arg Trp Leu Arg Gln Val Ser Lys
                 275                 280                 285

 Val Ala Ser Gln Arg Ile Ser Ser Val Asp Leu Ser Cys Cys Ser
                 290                 295                 300

 Leu Glu His Leu Pro Ala Asn Leu Phe Tyr Ser Gln Asp Leu Thr
                 305                 310                 315

 His Leu Asn Leu Lys Gln Asn Phe Leu Arg Gln Asn Pro Ser Leu
                 320                 325                 330

 Pro Ala Ala Arg Gly Leu Asn Glu Leu Gln Arg Phe Thr Lys Leu
                 335                 340                 345

 Lys Ser Leu Asn Leu Ser Asn Asn His Leu Gly Asp Phe Pro Leu
                 350                 355                 360

 Ala Val Cys Ser Ile Pro Thr Leu Ala Glu Leu Asn Val Ser Cys
                 365                 370                 375

 Asn Ala Leu Arg Ser Val Pro Ala Ala Val Gly Val Met His Asn
                 380                 385                 390

 Leu Gln Thr Phe Leu Leu Asp Gly Asn Phe Leu Gln Ser Leu Pro
                 395                 400                 405

 Ala Glu Leu Glu Asn Met Lys Gln Leu Ser Tyr Leu Gly Leu Ser
                 410                 415                 420

 Phe Asn Glu Phe Thr Asp Ile Pro Glu Val Leu Glu Lys Leu Thr
                 425                 430                 435

 Ala Val Asp Lys Leu Cys Met Ser Gly Asn Cys Val Glu Thr Leu
                 440                 445                 450

 Arg Leu Gln Ala Leu Arg Lys Met Pro His Ile Lys His Val Asp
                 455                 460                 465

 Leu Arg Leu Asn Val Ile Arg Lys Leu Ile Ala Asp Glu Val Asp
                 470                 475                 480

 Phe Leu Gln His Val Thr Gln Leu Asp Leu Arg Asp Asn Lys Leu
                 485                 490                 495

 Gly Asp Leu Asp Ala Met Ile Phe Asn Asn Ile Glu Val Leu His
                 500                 505                 510

 Cys Glu Arg Asn Gln Leu Val Thr Leu Asp Ile Cys Gly Tyr Phe
                 515                 520                 525

 Leu Lys Ala Leu Tyr Ala Ser Ser Asn Glu Leu Val Gln Leu Asp
                 530                 535                 540

 Val Tyr Pro Val Pro Asn Tyr Leu Ser Tyr Met Asp Val Ser Arg
                 545                 550                 555

 Asn Arg Leu Glu Asn Val Pro Glu Trp Val Cys Glu Ser Arg Lys
                 560                 565                 570

 Leu Glu Val Leu Asp Ile Gly His Asn Gln Ile Cys Glu Leu Pro
                 575                 580                 585

 Ala Arg Leu Phe Cys Asn Ser Ser Leu Arg Lys Leu Leu Ala Gly
                 590                 595                 600

 His Asn Gln Leu Ala Arg Leu Pro Glu Arg Leu Glu Arg Thr Ser
                 605                 610                 615

 Val Glu Val Leu Asp Val Gln His Asn Gln Leu Leu Glu Leu Pro
                 620                 625                 630

 Pro Asn Leu Leu Met Lys Ala Asp Ser Leu Arg Phe Leu Asn Ala
                 635                 640                 645

 Ser Ala Asn Lys Leu Glu Ser Leu Pro Pro Ala Thr Leu Ser Glu
                 650                 655                 660

 Glu Thr Asn Ser Ile Leu Gln Glu Leu Tyr Leu Thr Asn Asn Ser
                 665                 670                 675

 Leu Thr Asp Lys Cys Val Pro Leu Leu Thr Gly His Pro His Leu
                 680                 685                 690

 Lys Ile Leu His Met Ala Tyr Asn Arg Leu Gln Ser Phe Pro Ala
                 695                 700                 705

 Ser Lys Met Ala Lys Leu Glu Glu Leu Glu Glu Ile Asp Leu Ser
                 710                 715                 720

 Gly Asn Lys Leu Lys Ala Ile Pro Thr Thr Ile Met Asn Cys Ser
                 725                 730                 735

 Arg Met His Thr Val Ile Ala His Ser Asn Cys Ile Glu Val Phe
                 740                 745                 750

 Pro Glu Val Met Gln Leu Pro Glu Ile Lys Cys Val Asp Leu Ser
                 755                 760                 765

 Cys Asn Glu Leu Ser Glu Val Thr Leu Pro Glu Asn Leu Pro Pro
                 770                 775                 780

 Lys Leu Gln Glu Leu Asp Leu Thr Gly Asn Pro Arg Leu Val Leu
                 785                 790                 795

 Asp His Lys Thr Leu Glu Leu Leu Asn Asn Ile Arg Cys Phe Lys
                 800                 805                 810

 Ile Asp Gln Pro Ser Thr Gly Asp Ala Ser Gly Ala Pro Ala Val
                 815                 820                 825

 Trp Ser His Gly Tyr Thr Glu Ala Ser Gly Val Lys Asn Lys Leu
                 830                 835                 840

 Cys Val Ala Ala Leu Ser Val Asn Asn Phe Cys Asp Asn Arg Glu
                 845                 850                 855

 Ala Leu Tyr Gly Val Phe Asp Gly Asp Arg Asn Val Glu Val Pro
                 860                 865                 870

 Tyr Leu Leu Gln Cys Thr Met Ser Asp Ile Leu Ala Glu Glu Leu
                 875                 880                 885

 Gln Lys Thr Lys Asn Glu Glu Glu Tyr Met Val Asn Thr Phe Ile
                 890                 895                 900

 Val Met Gln Arg Lys Leu Gly Thr Ala Gly Gln Lys Leu Gly Gly
                 905                 910                 915

 Ala Ala Val Leu Cys His Ile Lys His Asp Pro Val Asp Pro Gly
                 920                 925                 930

 Gly Ser Phe Thr Leu Thr Ser Ala Asn Val Gly Lys Cys Gln Thr
                 935                 940                 945

 Val Leu Cys Arg Asn Gly Lys Pro Leu Pro Leu Ser Arg Ser Tyr
                 950                 955                 960

 Ile Met Ser Cys Glu Glu Glu Leu Lys Arg Ile Lys Gln His Lys
                 965                 970                 975

 Ala Ile Ile Thr Glu Asp Gly Lys Val Asn Gly Val Thr Glu Ser
                 980                 985                 990

 Thr Arg Ile Leu Gly Tyr Thr Phe Leu His Pro Ser Val Val Pro
                 995                1000                1005

 Arg Pro His Val Gln Ser Val Leu Leu Thr Pro Gln Asp Glu Phe
                1010                1015                1020

 Phe Ile Leu Gly Ser Lys Gly Leu Trp Asp Ser Leu Ser Val Glu
                1025                1030                1035

 Glu Ala Val Glu Ala Val Arg Asn Val Pro Asp Ala Leu Ala Ala
                1040                1045                1050

 Ala Lys Lys Leu Cys Thr Leu Ala Gln Ser Tyr Gly Cys His Asp
                1055                1060                1065

 Ser Ile Ser Ala Val Val Val Gln Leu Ser Val Thr Glu Asp Ser
                1070                1075                1080

 Phe Cys Cys Cys Glu Leu Ser Ala Gly Gly Ala Val Pro Pro Pro
                1085                1090                1095

 Ser Pro Gly Ile Phe Pro Pro Ser Val Asn Met Val Ile Lys Asp
                1100                1105                1110

 Arg Pro Ser Asp Gly Leu Gly Val Pro Ser Ser Ser Ser Gly Met
                1115                1120                1125

 Ala Ser Glu Ile Ser Ser Glu Leu Ser Thr Ser Glu Met Ser Ser
                1130                1135                1140

 Glu Val Gly Ser Thr Ala Ser Asp Glu Pro Pro Pro Gly Ala Leu
                1145                1150                1155

 Ser Glu Asn Ser Pro Ala Tyr Pro Ser Glu Gln Arg Cys Met Leu
                1160                1165                1170

 His Pro Ile Cys Leu Ser Asn Ser Phe Gln Arg Gln Leu Ser Ser
                1175                1180                1185

 Ala Thr Phe Ser Ser Ala Phe Ser Asp Asn Gly Leu Asp Ser Asp
                1190                1195                1200

 Asp Glu Glu Pro Ile Glu Gly Val Phe Thr Asn Gly Ser Arg Val
                1205                1210                1215

 Glu Val Glu Val Asp Ile His Cys Ser Arg Ala Lys Glu Lys Glu
                1220                1225                1230

 Lys Gln Gln His Leu Leu Gln Val Pro Ala Glu Ala Ser Asp Glu
                1235                1240                1245

 Gly Ile Val Ile Ser Ala Asn Glu Asp Glu Pro Gly Leu Pro Arg
                1250                1255                1260

 Lys Ala Asp Phe Ser Ala Val Gly Thr Ile Gly Arg Arg Arg Ala
                1265                1270                1275

 Asn Gly Ser Val Ala Pro Gln Glu Arg Ser His Asn Val Ile Glu
                1280                1285                1290

 Val Ala Thr Asp Ala Pro Leu Arg Lys Pro Gly Gly Tyr Phe Ala
                1295                1300                1305

 Ala Pro Ala Gln Pro Asp Pro Asp Asp Gln Phe Ile Ile Pro Pro
                1310                1315                1320

 Glu Leu Glu Glu Glu Val Lys Glu Ile Met Lys His His Gln Glu
                1325                1330                1335

 Gln Gln Gln Gln Gln Gln Pro Pro Pro Pro Pro Gln Leu Gln Pro
                1340                1345                1350

 Gln Leu Pro Arg His Tyr Gln Leu Asp Gln Leu Pro Asp Tyr Tyr
                1355                1360                1365

 Asp Thr Pro Leu


<210> 5908
<211> 2049
<212> DNA
<213> Homo sapien

<400> 5908
 ggcacgaggg ggagtaggca gcggcgccgc gtccgctctc gcccgctctc 50

 gcccgctcgc cagccggctc tcctcccgcc gcaggacccg cgcgccgcgc 100

 tcgggggcca tgcagcgcct ggccatggac ctgcggatgt tgtcccggga 150

 gctctccctc tacctggaac accaagtccg ggtggggttc ttcggctcgg 200

 gggtgggctt atcccttatc ctgggcttca gcgtcgctta tgccttctac 250

 tacctgagca gcattgccaa gaaaccccag ttagtgaccg ggggtgagag 300

 tttcagccgc ttccttcaag accactgtcc cgtggttaca gaaacgtact 350

 acccgacggt ctggtgctgg gagggtcgag gacagaccct gcttagacct 400

 ttcatcactt cgaagccccc ggtgcagtac aggaatgaac ttattaaaac 450

 tgcagatgga ggacagattt cactggactg gtttgataat gataacagta 500

 cgtgttatat ggatgccagc accagaccta ctatcttatt gttgcctggc 550

 ctcacgggaa caagcaagga gtcatatatc cttcatatga tccatcttag 600

 tgaagaatta ggatacagat gtgtggtttt taacaacaga ggagtggcgg 650

 gggagaatct cttgacgcca aggacttatt gttgtgctaa cactgaagac 700

 ttggagacag ttattcacca tgtacacagc ctgtaccctt ctgctccttt 750

 cctggcagca ggggtttcaa tgggaggaat gctgcttcta aattacttgg 800

 gcaaaattgg gtccaaaacg cctttgatgg cagctgcaac tttttccgtt 850

 ggttggaaca ccttcgcttg ctcagagtca ttggaaaaac cactgaactg 900

 gctacttttt aattactatt tgacaacctg ccttcagtct tcagttaata 950

 agcaccgaca tatgtttgta aaacaagttg atatggatca tgtcatgaag 1000

 gctaaatcca tcagagagtt tgataagcga ttcacttcag tcatgtttgg 1050

 ataccaaaca attgatgatt attatactga tgccagtccg agtcctagac 1100

 tgaagtcagt aggaattcca gtattgtgtc taaattctgt ggatgatgtt 1150

 ttctcaccca gtcatgctat tccaatagaa actgctaagc aaaatcctaa 1200

 tgttgctttg gtccttactt cttatggagg ccatattggt tttctggagg 1250

 gaatctggcc aagacagtcc acttacatgg atcgtgtctt caagcaattt 1300

 gtgcaagcca tggttgagca tggacatgaa ctctcttaac atgtagttct 1350

 ttgggtgcat tttgtctgaa ccacaattgt gaaggcagct cagcttagtg 1400

 cacaaatttt aactgttgta tataaagcaa ataagccagc agatgggtga 1450

 agaggtccag aatgatatgc aaaaactact ttttagagaa acaaaacaac 1500

 tttgtagcaa caaattaaat atagtattag attgttactt acgtagattt 1550

 tatttttact atgccttacc aagtacatcc ttaaacaaag tagtatgtac 1600

 atgaaattgc acttaaccaa aactattgtg taaaacaaat tttaattcct 1650

 cagggtttta atttaaacta gtattttttt agattatttg ttttaggtga 1700

 tttaatggta ctttaataac tactaagaaa tattggctat ttcaatgtaa 1750

 gttataaggt ggtacattcc taagggtatt tatagttgat gataacatga 1800

 aaactgaaat aagataaaat acaacgtgct aaatctttta tgtattctaa 1850

 ctttaaaaga caagtgcaac aaagttagac tgacttctat atgtgctctt 1900

 ttactctgat aatattaaat taggactaac ttatgtttta taatgattat 1950

 aatttacatg cttattttta aaatagtata tgtggacaca tatatatcat 2000

 tatattaaaa taaattctac cattttaaat tggaaaaaaa aaaaaaaaa 2049

<210> 5909
<211> 409
<212> PRT
<213> Homo sapien

<400> 5909
 Met Gln Arg Leu Ala Met Asp Leu Arg Met Leu Ser Arg Glu Leu
   1               5                  10                  15

 Ser Leu Tyr Leu Glu His Gln Val Arg Val Gly Phe Phe Gly Ser
                  20                  25                  30

 Gly Val Gly Leu Ser Leu Ile Leu Gly Phe Ser Val Ala Tyr Ala
                  35                  40                  45

 Phe Tyr Tyr Leu Ser Ser Ile Ala Lys Lys Pro Gln Leu Val Thr
                  50                  55                  60

 Gly Gly Glu Ser Phe Ser Arg Phe Leu Gln Asp His Cys Pro Val
                  65                  70                  75

 Val Thr Glu Thr Tyr Tyr Pro Thr Val Trp Cys Trp Glu Gly Arg
                  80                  85                  90

 Gly Gln Thr Leu Leu Arg Pro Phe Ile Thr Ser Lys Pro Pro Val
                  95                 100                 105

 Gln Tyr Arg Asn Glu Leu Ile Lys Thr Ala Asp Gly Gly Gln Ile
                 110                 115                 120

 Ser Leu Asp Trp Phe Asp Asn Asp Asn Ser Thr Cys Tyr Met Asp
                 125                 130                 135

 Ala Ser Thr Arg Pro Thr Ile Leu Leu Leu Pro Gly Leu Thr Gly
                 140                 145                 150

 Thr Ser Lys Glu Ser Tyr Ile Leu His Met Ile His Leu Ser Glu
                 155                 160                 165

 Glu Leu Gly Tyr Arg Cys Val Val Phe Asn Asn Arg Gly Val Ala
                 170                 175                 180

 Gly Glu Asn Leu Leu Thr Pro Arg Thr Tyr Cys Cys Ala Asn Thr
                 185                 190                 195

 Glu Asp Leu Glu Thr Val Ile His His Val His Ser Leu Tyr Pro
                 200                 205                 210

 Ser Ala Pro Phe Leu Ala Ala Gly Val Ser Met Gly Gly Met Leu
                 215                 220                 225

 Leu Leu Asn Tyr Leu Gly Lys Ile Gly Ser Lys Thr Pro Leu Met
                 230                 235                 240

 Ala Ala Ala Thr Phe Ser Val Gly Trp Asn Thr Phe Ala Cys Ser
                 245                 250                 255

 Glu Ser Leu Glu Lys Pro Leu Asn Trp Leu Leu Phe Asn Tyr Tyr
                 260                 265                 270

 Leu Thr Thr Cys Leu Gln Ser Ser Val Asn Lys His Arg His Met
                 275                 280                 285

 Phe Val Lys Gln Val Asp Met Asp His Val Met Lys Ala Lys Ser
                 290                 295                 300

 Ile Arg Glu Phe Asp Lys Arg Phe Thr Ser Val Met Phe Gly Tyr
                 305                 310                 315

 Gln Thr Ile Asp Asp Tyr Tyr Thr Asp Ala Ser Pro Ser Pro Arg
                 320                 325                 330

 Leu Lys Ser Val Gly Ile Pro Val Leu Cys Leu Asn Ser Val Asp
                 335                 340                 345

 Asp Val Phe Ser Pro Ser His Ala Ile Pro Ile Glu Thr Ala Lys
                 350                 355                 360

 Gln Asn Pro Asn Val Ala Leu Val Leu Thr Ser Tyr Gly Gly His
                 365                 370                 375

 Ile Gly Phe Leu Glu Gly Ile Trp Pro Arg Gln Ser Thr Tyr Met
                 380                 385                 390

 Asp Arg Val Phe Lys Gln Phe Val Gln Ala Met Val Glu His Gly
                 395                 400                 405

 His Glu Leu Ser


<210> 5910
<211> 2121
<212> DNA
<213> Homo sapien

<400> 5910
 ctgctcgcgg ccgccaccgc cgggccccgg ccgtccctgg ctcccctcct 50

 gcctcgagaa gggcagggct tctcagaggc ttggcgggaa aaaagaacgg 100

 agggagggat cgcgctgagt ataaaagccg gttttcgggg ctttatctaa 150

 ctcgctgtag taattccagc gagaggcaga gggagcgagc gggcggccgg 200

 ctagggtgga agagccgggc gagcagagct gcgctgcggg cgtcctggga 250

 agggagatcc ggagcgaata gggggcttcg cctctggccc agccctcccg 300

 cttgatcccc caggccagcg gtccgcaacc cttgccgcat ccacgaaact 350

 ttgcccatag cagcgggcgg gcactttgca ctggaactta caacacccga 400

 gcaaggacgc gactctcccg acgcggggag gctattctgc ccatttgggg 450

 acacttcccc gccgctgcca ggacccgctt ctctgaaagg ctctccttgc 500

 agctgcttag acgctggatt tttttcgggt agtggaaaac cagcagcctc 550

 ccgcgacgat gcccctcaac gttagcttca ccaacaggaa ctatgacctc 600

 gactacgact cggtgcagcc gtatttctac tgcgacgagg aggagaactt 650

 ctaccagcag cagcagcaga gcgagctgca gcccccggcg cccagcgagg 700

 atatctggaa gaaattcgag ctgctgccca ccccgcccct gtcccctagc 750

 cgccgctccg ggctctgctc gccctcctac gttgcggtca cacccttctc 800

 ccttcgggga gacaacgacg gcggtggcgg gagcttctcc acggccgacc 850

 agctggagat ggtgaccgag ctgctgggag gagacatggt gaaccagagt 900

 ttcatctgcg acccggacga cgagaccttc atcaaaaaca tcatcatcca 950

 ggactgtatg tggagcggct tctcggccgc cgccaagctc gtctcagaga 1000

 agctggcctc ctaccaggct gcgcgcaaag acagcggcag cccgaacccc 1050

 gcccgcggcc acagcgtctg ctccacctcc agcttgtacc tgcaggatct 1100

 gagcgccgcc gcctcagagt gcatcgaccc ctcggtggtc ttcccctacc 1150

 ctctcaacga cagcagctcg cccaagtcct gcgcctcgca agactccagc 1200

 gccttctctc cgtcctcgga ttctctgctc tcctcgacgg agtcctcccc 1250

 gcagggcagc cccgagcccc tggtgctcca tgaggagaca ccgcccacca 1300

 ccagcagcga ctctgaggag gaacaagaag atgaggaaga aatcgatgtt 1350

 gtttctgtgg aaaagaggca ggctcctggc aaaaggtcag agtctggatc 1400

 accttctgct ggaggccaca gcaaacctcc tcacagccca ctggtcctca 1450

 agaggtgcca cgtctccaca catcagcaca actacgcagc gcctccctcc 1500

 actcggaagg actatcctgc tgccaagagg gtcaagttgg acagtgtcag 1550

 agtcctgaga cagatcagca acaaccgaaa atgcaccagc cccaggtcct 1600

 cggacaccga ggagaatgtc aagaggcgaa cacacaacgt cttggagcgc 1650

 cagaggagga acgagctaaa acggagcttt tttgccctgc gtgaccagat 1700

 cccggagttg gaaaacaatg aaaaggcccc caaggtagtt atccttaaaa 1750

 aagccacagc atacatcctg tccgtccaag cagaggagca aaagctcatt 1800

 tctgaagagg acttgttgcg gaaacgacga gaacagttga aacacaaact 1850

 tgaacagcta cggaactctt gtgcgtaagg aaaagtaagg aaaacgattc 1900

 cttctaacag aaatgtcctg agcaatcacc tatgaacttg tttcaaatgc 1950

 atgatcaaat gcaacctcac aaccttggct gagtcttgag actgaaagat 2000

 ttagccataa tgtaaactgc ctcaaattgg actttgggca taaaagaact 2050

 tttttatgct taccatcttt tttttttctt taacagattt gtatttaaga 2100

 attgttttta aaaaatttta a 2121

<210> 5911
<211> 439
<212> PRT
<213> Homo sapien

<400> 5911
 Met Pro Leu Asn Val Ser Phe Thr Asn Arg Asn Tyr Asp Leu Asp
   1               5                  10                  15

 Tyr Asp Ser Val Gln Pro Tyr Phe Tyr Cys Asp Glu Glu Glu Asn
                  20                  25                  30

 Phe Tyr Gln Gln Gln Gln Gln Ser Glu Leu Gln Pro Pro Ala Pro
                  35                  40                  45

 Ser Glu Asp Ile Trp Lys Lys Phe Glu Leu Leu Pro Thr Pro Pro
                  50                  55                  60

 Leu Ser Pro Ser Arg Arg Ser Gly Leu Cys Ser Pro Ser Tyr Val
                  65                  70                  75

 Ala Val Thr Pro Phe Ser Leu Arg Gly Asp Asn Asp Gly Gly Gly
                  80                  85                  90

 Gly Ser Phe Ser Thr Ala Asp Gln Leu Glu Met Val Thr Glu Leu
                  95                 100                 105

 Leu Gly Gly Asp Met Val Asn Gln Ser Phe Ile Cys Asp Pro Asp
                 110                 115                 120

 Asp Glu Thr Phe Ile Lys Asn Ile Ile Ile Gln Asp Cys Met Trp
                 125                 130                 135

 Ser Gly Phe Ser Ala Ala Ala Lys Leu Val Ser Glu Lys Leu Ala
                 140                 145                 150

 Ser Tyr Gln Ala Ala Arg Lys Asp Ser Gly Ser Pro Asn Pro Ala
                 155                 160                 165

 Arg Gly His Ser Val Cys Ser Thr Ser Ser Leu Tyr Leu Gln Asp
                 170                 175                 180

 Leu Ser Ala Ala Ala Ser Glu Cys Ile Asp Pro Ser Val Val Phe
                 185                 190                 195

 Pro Tyr Pro Leu Asn Asp Ser Ser Ser Pro Lys Ser Cys Ala Ser
                 200                 205                 210

 Gln Asp Ser Ser Ala Phe Ser Pro Ser Ser Asp Ser Leu Leu Ser
                 215                 220                 225

 Ser Thr Glu Ser Ser Pro Gln Gly Ser Pro Glu Pro Leu Val Leu
                 230                 235                 240

 His Glu Glu Thr Pro Pro Thr Thr Ser Ser Asp Ser Glu Glu Glu
                 245                 250                 255

 Gln Glu Asp Glu Glu Glu Ile Asp Val Val Ser Val Glu Lys Arg
                 260                 265                 270

 Gln Ala Pro Gly Lys Arg Ser Glu Ser Gly Ser Pro Ser Ala Gly
                 275                 280                 285

 Gly His Ser Lys Pro Pro His Ser Pro Leu Val Leu Lys Arg Cys
                 290                 295                 300

 His Val Ser Thr His Gln His Asn Tyr Ala Ala Pro Pro Ser Thr
                 305                 310                 315

 Arg Lys Asp Tyr Pro Ala Ala Lys Arg Val Lys Leu Asp Ser Val
                 320                 325                 330

 Arg Val Leu Arg Gln Ile Ser Asn Asn Arg Lys Cys Thr Ser Pro
                 335                 340                 345

 Arg Ser Ser Asp Thr Glu Glu Asn Val Lys Arg Arg Thr His Asn
                 350                 355                 360

 Val Leu Glu Arg Gln Arg Arg Asn Glu Leu Lys Arg Ser Phe Phe
                 365                 370                 375

 Ala Leu Arg Asp Gln Ile Pro Glu Leu Glu Asn Asn Glu Lys Ala
                 380                 385                 390

 Pro Lys Val Val Ile Leu Lys Lys Ala Thr Ala Tyr Ile Leu Ser
                 395                 400                 405

 Val Gln Ala Glu Glu Gln Lys Leu Ile Ser Glu Glu Asp Leu Leu
                 410                 415                 420

 Arg Lys Arg Arg Glu Gln Leu Lys His Lys Leu Glu Gln Leu Arg
                 425                 430                 435

 Asn Ser Cys Ala


<210> 5912
<211> 3925
<212> DNA
<213> Homo sapien

<400> 5912
 acagcacaga cagattgacc tattggggtg tttcgcgagt gtgagaggga 50

 agcgccgcgg cctgtatttc tagacctgcc cttcgcctgg ttcgtggcgc 100

 cttgtgaccc cgggcccctg ccgcctgcaa gtcggaaatt gcgctgtgct 150

 cctgtgctac ggcctgtggc tggactgcct gctgctgccc aactggctgg 200

 caagatgaag ctctccctgg tggccgcgat gctgctgctg ctcagcgcgg 250

 cgcgggccga ggaggaggac aagaaggagg acgtgggcac ggtggtcggc 300

 atcgacctgg ggaccaccta ctcctgcgtc ggcgtgttca agaacggccg 350

 cgtggagatc atcgccaacg atcagggcaa ccgcatcacg ccgtcctatg 400

 tcgccttcac tcctgaaggg gaacgtctga ttggcgatgc cgccaagaac 450

 cagctcacct ccaaccccga gaacacggtc tttgacgcca agcggctcat 500

 cggccgcacg tggaatgacc cgtctgtgca gcaggacatc aagttcttgc 550

 cgttcaaggt ggttgaaaag aaaactaaac catacattca agttgatatt 600

 ggaggtgggc aaacaaagac atttgctcct gaagaaattt ctgccatggt 650

 tctcactaaa atgaaagaaa ccgctgaggc ttatttggga aagaaggtta 700

 cccatgcagt tgttactgta ccagcctatt ttaatgatgc ccaacgccaa 750

 gcaaccaaag acgctggaac tattgctggc ctaaatgtta tgaggatcat 800

 caacgagcct acggcagctg ctattgctta tggcctggat aagagggagg 850

 gggagaagaa catcctggtg tttgacctgg gtggcggaac cttcgatgtg 900

 tctcttctca ccattgacaa tggtgtcttc gaagttgtgg ccactaatgg 950

 agatactcat ctgggtggag aagactttga ccagcgtgtc atggaacact 1000

 tcatcaaact gtacaaaaag aagacgggca aagatgtcag gaaagacaat 1050

 agagctgtgc agaaactccg gcgcgaggta gaaaaggcca aacgggccct 1100

 gtcttctcag catcaagcaa gaattgaaat tgagtccttc tatgaaggag 1150

 aagacttttc tgagaccctg actcgggcca aatttgaaga gctcaacatg 1200

 gatctgttcc ggtctactat gaagcccgtc cagaaagtgt tggaagattc 1250

 tgatttgaag aagtctgata ttgatgaaat tgttcttgtt ggtggctcga 1300

 ctcgaattcc aaagattcag caactggtta aagagttctt caatggcaag 1350

 gaaccatccc gtggcataaa cccagatgaa gctgtagcgt atggtgctgc 1400

 tgtccaggct ggtgtgctct ctggtgatca agatacaggt gacctggtac 1450

 tgcttgatgt atgtcccctt acacttggta ttgaaactgt gggaggtgtc 1500

 atgaccaaac tgattccaag gaacacagtg gtgcctacca agaagtctca 1550

 gatcttttct acagcttctg ataatcaacc aactgttaca atcaaggtct 1600

 atgaaggtga aagacccctg acaaaagaca atcatcttct gggtacattt 1650

 gatctgactg gaattcctcc tgctcctcgt ggggtcccac agattgaagt 1700

 cacctttgag atagatgtga atggtattct tcgagtgaca gctgaagaca 1750

 agggtacagg gaacaaaaat aagatcacaa tcaccaatga ccagaatcgc 1800

 ctgacacctg aagaaatcga aaggatggtt aatgatgctg agaagtttgc 1850

 tgaggaagac aaaaagctca aggagcgcat tgatactaga aatgagttgg 1900

 aaagctatgc ctattctcta aagaatcaga ttggagataa agaaaagctg 1950

 ggaggtaaac tttcctctga agataaggag accatggaaa aagctgtaga 2000

 agaaaagatt gaatggctgg aaagccacca agatgctgac attgaagact 2050

 tcaaagctaa gaagaaggaa ctggaagaaa ttgttcaacc aattatcagc 2100

 aaactctatg gaagtgcagg ccctccccca actggtgaag aggatacagc 2150

 agaaaaagat gagttgtaga cactgatctg ctagtgctgt aatattgtaa 2200

 atactggact caggaacttt tgttaggaaa aaattgaaag aacttaagtc 2250

 tcgaatgtaa ttggaatctt cacctcagag tggagttgaa actgctatag 2300

 cctaagcggc tgtttactgc ttttcattag cagttgctca catgtctttg 2350

 ggtggggggg agaagaagaa ttggccatct taaaaagcag gtaaaaaacc 2400

 tgggttaggg tgtgtgttca ccttcaaaat gttctattta acaactgggt 2450

 catgtgcatc tggtgtagga agttttttct accataagtg acaccaataa 2500

 atgtttgtta tttacactgg tctaatgttt gtgagaagct tctaattaga 2550

 tcaattactt attttaggaa atttaagact agatactcgt gtgtggggtg 2600

 aggggaggga gtatttggta tgttgggata aggaaacact tctatttaat 2650

 gcttccaggg attttttttt ttttttttta accctcctgg gcccaagtga 2700

 tccttccacc tcagtctccc agctaattga gaccacaggc ttgttaccac 2750

 catgctcggc ttttgcatta atctaagaaa aggggagaga agttaatcca 2800

 catctttact caggcaaggg gcatttcaca gtgcccaaga gtggggtttt 2850

 cttgaacata cttggtttcc tatttcccct tatctttcta aaactgcctt 2900

 tctggtggct ttttttaaaa ttattactaa tgatgctttt atagctgctt 2950

 ggattctctg agaaatgatg gggagtgagt gatcactggt attaacttta 3000

 tacacttgga tttcatttgt aactttagga tgtaaaggta tattgtgaac 3050

 cctagctgtg tcagaatctc catccctgaa atttctcatt agtggtactg 3100

 gggtgggatc ttggatggtg acattgaaac tacactaaat cccctcacta 3150

 tgaatgggtt gttaaaggca atggtttgtg tcaaaactgg tttaggatta 3200

 cttagattgt gttcctgaag aaaagagtcc aggtaaatgg tatgatcaat 3250

 aaaggacagg ctggtgctaa cataaaatcc aatattgtaa tcctagcact 3300

 ttgggaggcc aaggcgggtg gatcacaagg tcaagagata gagaccatct 3350

 ttgccaacat ggtgaaactc catctctact gaaaatacaa aaattagctg 3400

 ggcgtggtag tgcaagctga aggctgaggc aggagaatca ctcgaacccg 3450

 ggaggcagag gttgcagtga gccgagatca caccactgta ctccagcccg 3500

 gcactccagc ctggcgacaa gagtgagact ccacctcaaa aaaaaaaaaa 3550

 agaatccaat actgcccaag gataggtatt ttatagatgg gcaactggct 3600

 gaaaggttaa ttctctaggg ctagtagaac tggatcccaa caccaaactc 3650

 ttaattagac ctaggcctca gctgcactgc ccgaaaagca tttgggcaga 3700

 ccctgagcag aatactggtc tcaggccaag cccaatacag ccattaaaga 3750

 tgacctacag tgctgtgtac cctggggcaa tagggttaaa tggtagttag 3800

 caactagggc tagtcttccc ttacctcaaa ggctctcact accgtggacc 3850

 acctagtctg taactctttc tgaggagctg ttactgaata ttaaaaagat 3900

 agacttcaaa aaaaaaaaaa aaaaa 3925

<210> 5913
<211> 654
<212> PRT
<213> Homo sapien

<400> 5913
 Met Lys Leu Ser Leu Val Ala Ala Met Leu Leu Leu Leu Ser Ala
   1               5                  10                  15

 Ala Arg Ala Glu Glu Glu Asp Lys Lys Glu Asp Val Gly Thr Val
                  20                  25                  30

 Val Gly Ile Asp Leu Gly Thr Thr Tyr Ser Cys Val Gly Val Phe
                  35                  40                  45

 Lys Asn Gly Arg Val Glu Ile Ile Ala Asn Asp Gln Gly Asn Arg
                  50                  55                  60

 Ile Thr Pro Ser Tyr Val Ala Phe Thr Pro Glu Gly Glu Arg Leu
                  65                  70                  75

 Ile Gly Asp Ala Ala Lys Asn Gln Leu Thr Ser Asn Pro Glu Asn
                  80                  85                  90

 Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Thr Trp Asn Asp
                  95                 100                 105

 Pro Ser Val Gln Gln Asp Ile Lys Phe Leu Pro Phe Lys Val Val
                 110                 115                 120

 Glu Lys Lys Thr Lys Pro Tyr Ile Gln Val Asp Ile Gly Gly Gly
                 125                 130                 135

 Gln Thr Lys Thr Phe Ala Pro Glu Glu Ile Ser Ala Met Val Leu
                 140                 145                 150

 Thr Lys Met Lys Glu Thr Ala Glu Ala Tyr Leu Gly Lys Lys Val
                 155                 160                 165

 Thr His Ala Val Val Thr Val Pro Ala Tyr Phe Asn Asp Ala Gln
                 170                 175                 180

 Arg Gln Ala Thr Lys Asp Ala Gly Thr Ile Ala Gly Leu Asn Val
                 185                 190                 195

 Met Arg Ile Ile Asn Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly
                 200                 205                 210

 Leu Asp Lys Arg Glu Gly Glu Lys Asn Ile Leu Val Phe Asp Leu
                 215                 220                 225

 Gly Gly Gly Thr Phe Asp Val Ser Leu Leu Thr Ile Asp Asn Gly
                 230                 235                 240

 Val Phe Glu Val Val Ala Thr Asn Gly Asp Thr His Leu Gly Gly
                 245                 250                 255

 Glu Asp Phe Asp Gln Arg Val Met Glu His Phe Ile Lys Leu Tyr
                 260                 265                 270

 Lys Lys Lys Thr Gly Lys Asp Val Arg Lys Asp Asn Arg Ala Val
                 275                 280                 285

 Gln Lys Leu Arg Arg Glu Val Glu Lys Ala Lys Arg Ala Leu Ser
                 290                 295                 300

 Ser Gln His Gln Ala Arg Ile Glu Ile Glu Ser Phe Tyr Glu Gly
                 305                 310                 315

 Glu Asp Phe Ser Glu Thr Leu Thr Arg Ala Lys Phe Glu Glu Leu
                 320                 325                 330

 Asn Met Asp Leu Phe Arg Ser Thr Met Lys Pro Val Gln Lys Val
                 335                 340                 345

 Leu Glu Asp Ser Asp Leu Lys Lys Ser Asp Ile Asp Glu Ile Val
                 350                 355                 360

 Leu Val Gly Gly Ser Thr Arg Ile Pro Lys Ile Gln Gln Leu Val
                 365                 370                 375

 Lys Glu Phe Phe Asn Gly Lys Glu Pro Ser Arg Gly Ile Asn Pro
                 380                 385                 390

 Asp Glu Ala Val Ala Tyr Gly Ala Ala Val Gln Ala Gly Val Leu
                 395                 400                 405

 Ser Gly Asp Gln Asp Thr Gly Asp Leu Val Leu Leu Asp Val Cys
                 410                 415                 420

 Pro Leu Thr Leu Gly Ile Glu Thr Val Gly Gly Val Met Thr Lys
                 425                 430                 435

 Leu Ile Pro Arg Asn Thr Val Val Pro Thr Lys Lys Ser Gln Ile
                 440                 445                 450

 Phe Ser Thr Ala Ser Asp Asn Gln Pro Thr Val Thr Ile Lys Val
                 455                 460                 465

 Tyr Glu Gly Glu Arg Pro Leu Thr Lys Asp Asn His Leu Leu Gly
                 470                 475                 480

 Thr Phe Asp Leu Thr Gly Ile Pro Pro Ala Pro Arg Gly Val Pro
                 485                 490                 495

 Gln Ile Glu Val Thr Phe Glu Ile Asp Val Asn Gly Ile Leu Arg
                 500                 505                 510

 Val Thr Ala Glu Asp Lys Gly Thr Gly Asn Lys Asn Lys Ile Thr
                 515                 520                 525

 Ile Thr Asn Asp Gln Asn Arg Leu Thr Pro Glu Glu Ile Glu Arg
                 530                 535                 540

 Met Val Asn Asp Ala Glu Lys Phe Ala Glu Glu Asp Lys Lys Leu
                 545                 550                 555

 Lys Glu Arg Ile Asp Thr Arg Asn Glu Leu Glu Ser Tyr Ala Tyr
                 560                 565                 570

 Ser Leu Lys Asn Gln Ile Gly Asp Lys Glu Lys Leu Gly Gly Lys
                 575                 580                 585

 Leu Ser Ser Glu Asp Lys Glu Thr Met Glu Lys Ala Val Glu Glu
                 590                 595                 600

 Lys Ile Glu Trp Leu Glu Ser His Gln Asp Ala Asp Ile Glu Asp
                 605                 610                 615

 Phe Lys Ala Lys Lys Lys Glu Leu Glu Glu Ile Val Gln Pro Ile
                 620                 625                 630

 Ile Ser Lys Leu Tyr Gly Ser Ala Gly Pro Pro Pro Thr Gly Glu
                 635                 640                 645

 Glu Asp Thr Ala Glu Lys Asp Glu Leu
                 650

<210> 5914
<211> 1080
<212> DNA
<213> Homo sapien

<400> 5914
 tggtcccttt ccttccaagg cccccgagag gaaggcatgc ggtgggccct 50

 agtggtgctt ctagctttcc tgtctcctgc cagtcagaaa tcttccaact 100

 tggaagggag aacgaagtca gtcaccaggc agactgggtc atctgctgaa 150

 atcacttgcg atcttactgt aacaaatacc ttctacatcc actggtacct 200

 acaccaggag gggaaggccc cacagcgtct tctgtactat gacgtctcca 250

 ccgcaaggga tgtgttggaa tcaggactca gtccaggaaa gtattatact 300

 catacaccca ggaggtggag ctggatattg agactgcaaa atctaattga 350

 aaatgattct ggggtctatt actgtgccac ctgggacagg ccccgcctta 400

 agaaactctt tggcagtgga acaacacttg ttgtcacaga taaacaactt 450

 gatgcagatg tttcccccaa gcccactatt tttcttcctt cgattgctga 500

 aacaaaactc cagaaggctg gaacatacct ttgtcttctt gagaaatttt 550

 tcccagatat tattaagata cattggcaag aaaagaagag caacacgatt 600

 ctgggatccc aggaggggaa caccatgaag actaacgaca catacatgaa 650

 atttagctgg ttaacggtgc cagaagagtc actggacaaa gaacacagat 700

 gtatcgtcag acatgagaat aataaaaacg gaattgatca agaaattatc 750

 tttcctccaa taaagacaga tgtcaccaca gtggatccca aatacaatta 800

 ttcaaaggat gcaaatgatg tcatcacaat ggatcccaaa gacaattggt 850

 caaaagatgc aaatgataca ctactgctgc agctcacaaa cacctctgca 900

 tattacacgt acctcctcct gctcctcaag agtgtggtct attttgccat 950

 catcacctgc tgtctgctta gaagaacggc tttctgctgc aatggagaga 1000

 aatcataaca gacggtggca caaggaggcc atcttttcct catcggttat 1050

 tgtccctaga agcgtccccg aattcaaggt 1080

<210> 5915
<211> 323
<212> PRT
<213> Homo sapien

<400> 5915
 Met Arg Trp Ala Leu Val Val Leu Leu Ala Phe Leu Ser Pro Ala
   1               5                  10                  15

 Ser Gln Lys Ser Ser Asn Leu Glu Gly Arg Thr Lys Ser Val Thr
                  20                  25                  30

 Arg Gln Thr Gly Ser Ser Ala Glu Ile Thr Cys Asp Leu Thr Val
                  35                  40                  45

 Thr Asn Thr Phe Tyr Ile His Trp Tyr Leu His Gln Glu Gly Lys
                  50                  55                  60

 Ala Pro Gln Arg Leu Leu Tyr Tyr Asp Val Ser Thr Ala Arg Asp
                  65                  70                  75

 Val Leu Glu Ser Gly Leu Ser Pro Gly Lys Tyr Tyr Thr His Thr
                  80                  85                  90

 Pro Arg Arg Trp Ser Trp Ile Leu Arg Leu Gln Asn Leu Ile Glu
                  95                 100                 105

 Asn Asp Ser Gly Val Tyr Tyr Cys Ala Thr Trp Asp Arg Pro Arg
                 110                 115                 120

 Leu Lys Lys Leu Phe Gly Ser Gly Thr Thr Leu Val Val Thr Asp
                 125                 130                 135

 Lys Gln Leu Asp Ala Asp Val Ser Pro Lys Pro Thr Ile Phe Leu
                 140                 145                 150

 Pro Ser Ile Ala Glu Thr Lys Leu Gln Lys Ala Gly Thr Tyr Leu
                 155                 160                 165

 Cys Leu Leu Glu Lys Phe Phe Pro Asp Ile Ile Lys Ile His Trp
                 170                 175                 180

 Gln Glu Lys Lys Ser Asn Thr Ile Leu Gly Ser Gln Glu Gly Asn
                 185                 190                 195

 Thr Met Lys Thr Asn Asp Thr Tyr Met Lys Phe Ser Trp Leu Thr
                 200                 205                 210

 Val Pro Glu Glu Ser Leu Asp Lys Glu His Arg Cys Ile Val Arg
                 215                 220                 225

 His Glu Asn Asn Lys Asn Gly Ile Asp Gln Glu Ile Ile Phe Pro
                 230                 235                 240

 Pro Ile Lys Thr Asp Val Thr Thr Val Asp Pro Lys Tyr Asn Tyr
                 245                 250                 255

 Ser Lys Asp Ala Asn Asp Val Ile Thr Met Asp Pro Lys Asp Asn
                 260                 265                 270

 Trp Ser Lys Asp Ala Asn Asp Thr Leu Leu Leu Gln Leu Thr Asn
                 275                 280                 285

 Thr Ser Ala Tyr Tyr Thr Tyr Leu Leu Leu Leu Leu Lys Ser Val
                 290                 295                 300

 Val Tyr Phe Ala Ile Ile Thr Cys Cys Leu Leu Arg Arg Thr Ala
                 305                 310                 315

 Phe Cys Cys Asn Gly Glu Lys Ser
                 320

<210> 5916
<211> 3453
<212> DNA
<213> Homo sapien

<400> 5916
 ttcaatgttg atgtgaaaaa ctcaatgact ttcagcggcc cggtggaaga 50

 catgtttgga tatactgttc aacaatatga aaatgaagaa ggaaaatggg 100

 tgcttattgg ttctccgtta gttggccaac ccaaaaacag aactggagat 150

 gtctataagt gtccagttgg gagaggtgaa tcattacctt gcgtaaagtt 200

 ggatctacca gttaatacat caattcccaa tgtcacagaa gtaaaggaga 250

 acatgacatt tggatcaact ttagtcacca acccaaatgg aggatttctg 300

 gcttgtgggc ccttatatgc ctatagatgt ggacatttgc attacacaac 350

 tggaatctgt tctgacgtca gccccacatt tcaagtcgtg aattccattg 400

 cccctgtaca agaatgcagc actcaactgg acatagtcat agtgctggat 450

 ggttccaaca gtatttaccc atgggacagt gttacagctt ttttaaatga 500

 cctcttgaaa agaatggata ttggtcctaa acagacacag gttggaattg 550

 tacagtatgg agaaaacgtg acccatgagt tcaacctcaa taagtattct 600

 tccaccgaag aggtacttgt tgcagcaaag aaaatagtcc agagaggtgg 650

 ccgccagact atgacagctc ttggaacaga cacagcaaga aaggaggcat 700

 tcacggaagc ccggggtgcc cgaagaggag ttaaaaaagt catggttatt 750

 gtgacagatg gagagtctca tgacaatcat cgactgaaga aggtcatcca 800

 agactgtgaa gatgaaaaca ttcaacggtt ttccatagct attcttggca 850

 gctataaccg aggaaattta agcactgaaa aatttgtgga ggaaataaaa 900

 tcaattgcaa gtgaacccac tgaaaagcat ttcttcaatg tctctgatga 950

 attggctcta gtcaccattg ttaaaactct gggagaaaga atatttgccc 1000

 tggaagccac agctgaccag tcagcagctt catttgaaat ggaaatgtct 1050

 cagactggct tcagtgctca ttattcacag gactgggtca tgcttggagc 1100

 agtaggagcc tatgattgga atggaacagt tgtcatgcag aaggctagtc 1150

 aaatcataat ccctcgaaac acaaccttta atgttgagtc taccaaaaag 1200

 aatgaaccgc ttgcttctta tttaggttac actgtaaact ctgctactgc 1250

 ttcttctgga gatgtgctct atattgctgg acagcctcgg tacaatcata 1300

 caggccaggt cattatctac aggatggaag atggaaacat caaaattctc 1350

 cagacgctca gtggagaaca gattggttcc tactttggca gtattttaac 1400

 aacaactgac attgacaagg attctaatac tgacattctt ctagtcggag 1450

 cccctatgta catgggaaca gagaaggagg agcaaggaaa agtgtatgtg 1500

 tatgctctca atcagacaag gtttgaatat caaatgagcc tggaacctat 1550

 taagcagacg tgctgttcat ctcggcagca caattcatgc acaacagaaa 1600

 acaaaaatga gccatgcggg gctcgttttg gaactgcaat tgctgctgta 1650

 aaagacctca atcttgatgg atttaatgac atcgtgatag gagctccgct 1700

 ggaagatgat cacgggggag ctgtgtacat ttatcatgga agtggcaaga 1750

 ctataaggaa agagtatgca caacgtattc catcaggtgg ggatggtaag 1800

 acactgaaat tttttggcca gtctatccac ggagaaatgg atttaaatgg 1850

 tgacggtctg acagatgtga ctattggggg ccttggtggt gctgccctct 1900

 tctggtcccg agatgtggcc gtagttaaag tgaccatgaa ttttgagcca 1950

 aataaagtga atattcaaaa gaaaaactgc catatggagg gaaaggaaac 2000

 agtatgcata aatgctacag tgtgttttga ggttaaatta aagtctaaag 2050

 aagacacgat ttatgaagct gatttgcagt accgtgtcac cctagattca 2100

 ctaagacaaa tatcacgaag ttttttctct ggaactcaag agagaaaggt 2150

 tcaaaggaac atcacagttc gaaaatcaga atgcactaag cactccttct 2200

 acatgttgga caagcatgac tttcaggact ctgtgagaat aacgttggac 2250

 tttaatctta ccgatccaga aaatgggcct gttcttgatg attctctacc 2300

 aaactcagta catgaatata ttccctttgc caaagattgt ggaaataagg 2350

 aaaaatgtat ctcagacctc agcctgcatg tcgccaccac tgaaaaggac 2400

 ctgctgattg tccgatccca gaatgataag ttcaacgtta gcctcacagt 2450

 caaaaataca aaggacagtg cctataacac caggacaata gtgcattatt 2500

 ctccaaatct agttttttca ggaattgagg ctatccaaaa agacagttgt 2550

 gaatctaatc ataatatcac atgtaaagtt ggatatccct tcctgagaag 2600

 aggagagatg gtaactttca aaatattgtt tcagtttaac acatcctatc 2650

 tcatggaaaa tgtgaccatt tatttaagtg caacaagtga cagcgaagaa 2700

 cctcctgaaa ccctttctga taatgtagta aacatttcta tcccggtaaa 2750

 atatgaagtt ggactacagt tttacagctc tgcaagtgaa taccacattt 2800

 caattgctgc caatgagaca gtccctgaag ttattaattc tactgaggac 2850

 attggaaatg aaattaatat cttctacttg attagaaaaa gtggatcttt 2900

 tccaatgcca gagcttaagc tgtcaatttc attccccaat atgacatcaa 2950

 atggttaccc tgtgctgtac ccaactggat tgtcatcttc tgagaatgca 3000

 aactgcagac cccatatctt tgaggatcct ttcagtatca actctggaaa 3050

 gaaaatgact acatcaactg accatctcaa acgaggcaca attctggact 3100

 gcaatacatg taaatttgct accatcacat gtaatctcac ttcttctgac 3150

 atcagccaag tcaatgtttc gcttatcttg tggaaaccaa cttttataaa 3200

 atcatatttt tccagcttaa atcttactat aaggggagaa cttcggagtg 3250

 aaaatgcatc tctggtttta agtagcagca atcaaaaaag agagcttgct 3300

 attcaaatat ccaaagatgg gctaccgggc agagtgccat tatgggtcat 3350

 cctgctgagt gcttttgccg gattgttgct gttaatgctg ctcattttag 3400

 cactgtggaa gattggattc ttcaaaagac cactgaaaaa gaaaatggag 3450

 aaa 3453

<210> 5917
<211> 1143
<212> PRT
<213> Homo sapien

<400> 5917
 Met Thr Phe Ser Gly Pro Val Glu Asp Met Phe Gly Tyr Thr Val
   1               5                  10                  15

 Gln Gln Tyr Glu Asn Glu Glu Gly Lys Trp Val Leu Ile Gly Ser
                  20                  25                  30

 Pro Leu Val Gly Gln Pro Lys Asn Arg Thr Gly Asp Val Tyr Lys
                  35                  40                  45

 Cys Pro Val Gly Arg Gly Glu Ser Leu Pro Cys Val Lys Leu Asp
                  50                  55                  60

 Leu Pro Val Asn Thr Ser Ile Pro Asn Val Thr Glu Val Lys Glu
                  65                  70                  75

 Asn Met Thr Phe Gly Ser Thr Leu Val Thr Asn Pro Asn Gly Gly
                  80                  85                  90

 Phe Leu Ala Cys Gly Pro Leu Tyr Ala Tyr Arg Cys Gly His Leu
                  95                 100                 105

 His Tyr Thr Thr Gly Ile Cys Ser Asp Val Ser Pro Thr Phe Gln
                 110                 115                 120

 Val Val Asn Ser Ile Ala Pro Val Gln Glu Cys Ser Thr Gln Leu
                 125                 130                 135

 Asp Ile Val Ile Val Leu Asp Gly Ser Asn Ser Ile Tyr Pro Trp
                 140                 145                 150

 Asp Ser Val Thr Ala Phe Leu Asn Asp Leu Leu Lys Arg Met Asp
                 155                 160                 165

 Ile Gly Pro Lys Gln Thr Gln Val Gly Ile Val Gln Tyr Gly Glu
                 170                 175                 180

 Asn Val Thr His Glu Phe Asn Leu Asn Lys Tyr Ser Ser Thr Glu
                 185                 190                 195

 Glu Val Leu Val Ala Ala Lys Lys Ile Val Gln Arg Gly Gly Arg
                 200                 205                 210

 Gln Thr Met Thr Ala Leu Gly Thr Asp Thr Ala Arg Lys Glu Ala
                 215                 220                 225

 Phe Thr Glu Ala Arg Gly Ala Arg Arg Gly Val Lys Lys Val Met
                 230                 235                 240

 Val Ile Val Thr Asp Gly Glu Ser His Asp Asn His Arg Leu Lys
                 245                 250                 255

 Lys Val Ile Gln Asp Cys Glu Asp Glu Asn Ile Gln Arg Phe Ser
                 260                 265                 270

 Ile Ala Ile Leu Gly Ser Tyr Asn Arg Gly Asn Leu Ser Thr Glu
                 275                 280                 285

 Lys Phe Val Glu Glu Ile Lys Ser Ile Ala Ser Glu Pro Thr Glu
                 290                 295                 300

 Lys His Phe Phe Asn Val Ser Asp Glu Leu Ala Leu Val Thr Ile
                 305                 310                 315

 Val Lys Thr Leu Gly Glu Arg Ile Phe Ala Leu Glu Ala Thr Ala
                 320                 325                 330

 Asp Gln Ser Ala Ala Ser Phe Glu Met Glu Met Ser Gln Thr Gly
                 335                 340                 345

 Phe Ser Ala His Tyr Ser Gln Asp Trp Val Met Leu Gly Ala Val
                 350                 355                 360

 Gly Ala Tyr Asp Trp Asn Gly Thr Val Val Met Gln Lys Ala Ser
                 365                 370                 375

 Gln Ile Ile Ile Pro Arg Asn Thr Thr Phe Asn Val Glu Ser Thr
                 380                 385                 390

 Lys Lys Asn Glu Pro Leu Ala Ser Tyr Leu Gly Tyr Thr Val Asn
                 395                 400                 405

 Ser Ala Thr Ala Ser Ser Gly Asp Val Leu Tyr Ile Ala Gly Gln
                 410                 415                 420

 Pro Arg Tyr Asn His Thr Gly Gln Val Ile Ile Tyr Arg Met Glu
                 425                 430                 435

 Asp Gly Asn Ile Lys Ile Leu Gln Thr Leu Ser Gly Glu Gln Ile
                 440                 445                 450

 Gly Ser Tyr Phe Gly Ser Ile Leu Thr Thr Thr Asp Ile Asp Lys
                 455                 460                 465

 Asp Ser Asn Thr Asp Ile Leu Leu Val Gly Ala Pro Met Tyr Met
                 470                 475                 480

 Gly Thr Glu Lys Glu Glu Gln Gly Lys Val Tyr Val Tyr Ala Leu
                 485                 490                 495

 Asn Gln Thr Arg Phe Glu Tyr Gln Met Ser Leu Glu Pro Ile Lys
                 500                 505                 510

 Gln Thr Cys Cys Ser Ser Arg Gln His Asn Ser Cys Thr Thr Glu
                 515                 520                 525

 Asn Lys Asn Glu Pro Cys Gly Ala Arg Phe Gly Thr Ala Ile Ala
                 530                 535                 540

 Ala Val Lys Asp Leu Asn Leu Asp Gly Phe Asn Asp Ile Val Ile
                 545                 550                 555

 Gly Ala Pro Leu Glu Asp Asp His Gly Gly Ala Val Tyr Ile Tyr
                 560                 565                 570

 His Gly Ser Gly Lys Thr Ile Arg Lys Glu Tyr Ala Gln Arg Ile
                 575                 580                 585

 Pro Ser Gly Gly Asp Gly Lys Thr Leu Lys Phe Phe Gly Gln Ser
                 590                 595                 600

 Ile His Gly Glu Met Asp Leu Asn Gly Asp Gly Leu Thr Asp Val
                 605                 610                 615

 Thr Ile Gly Gly Leu Gly Gly Ala Ala Leu Phe Trp Ser Arg Asp
                 620                 625                 630

 Val Ala Val Val Lys Val Thr Met Asn Phe Glu Pro Asn Lys Val
                 635                 640                 645

 Asn Ile Gln Lys Lys Asn Cys His Met Glu Gly Lys Glu Thr Val
                 650                 655                 660

 Cys Ile Asn Ala Thr Val Cys Phe Glu Val Lys Leu Lys Ser Lys
                 665                 670                 675

 Glu Asp Thr Ile Tyr Glu Ala Asp Leu Gln Tyr Arg Val Thr Leu
                 680                 685                 690

 Asp Ser Leu Arg Gln Ile Ser Arg Ser Phe Phe Ser Gly Thr Gln
                 695                 700                 705

 Glu Arg Lys Val Gln Arg Asn Ile Thr Val Arg Lys Ser Glu Cys
                 710                 715                 720

 Thr Lys His Ser Phe Tyr Met Leu Asp Lys His Asp Phe Gln Asp
                 725                 730                 735

 Ser Val Arg Ile Thr Leu Asp Phe Asn Leu Thr Asp Pro Glu Asn
                 740                 745                 750

 Gly Pro Val Leu Asp Asp Ser Leu Pro Asn Ser Val His Glu Tyr
                 755                 760                 765

 Ile Pro Phe Ala Lys Asp Cys Gly Asn Lys Glu Lys Cys Ile Ser
                 770                 775                 780

 Asp Leu Ser Leu His Val Ala Thr Thr Glu Lys Asp Leu Leu Ile
                 785                 790                 795

 Val Arg Ser Gln Asn Asp Lys Phe Asn Val Ser Leu Thr Val Lys
                 800                 805                 810

 Asn Thr Lys Asp Ser Ala Tyr Asn Thr Arg Thr Ile Val His Tyr
                 815                 820                 825

 Ser Pro Asn Leu Val Phe Ser Gly Ile Glu Ala Ile Gln Lys Asp
                 830                 835                 840

 Ser Cys Glu Ser Asn His Asn Ile Thr Cys Lys Val Gly Tyr Pro
                 845                 850                 855

 Phe Leu Arg Arg Gly Glu Met Val Thr Phe Lys Ile Leu Phe Gln
                 860                 865                 870

 Phe Asn Thr Ser Tyr Leu Met Glu Asn Val Thr Ile Tyr Leu Ser
                 875                 880                 885

 Ala Thr Ser Asp Ser Glu Glu Pro Pro Glu Thr Leu Ser Asp Asn
                 890                 895                 900

 Val Val Asn Ile Ser Ile Pro Val Lys Tyr Glu Val Gly Leu Gln
                 905                 910                 915

 Phe Tyr Ser Ser Ala Ser Glu Tyr His Ile Ser Ile Ala Ala Asn
                 920                 925                 930

 Glu Thr Val Pro Glu Val Ile Asn Ser Thr Glu Asp Ile Gly Asn
                 935                 940                 945

 Glu Ile Asn Ile Phe Tyr Leu Ile Arg Lys Ser Gly Ser Phe Pro
                 950                 955                 960

 Met Pro Glu Leu Lys Leu Ser Ile Ser Phe Pro Asn Met Thr Ser
                 965                 970                 975

 Asn Gly Tyr Pro Val Leu Tyr Pro Thr Gly Leu Ser Ser Ser Glu
                 980                 985                 990

 Asn Ala Asn Cys Arg Pro His Ile Phe Glu Asp Pro Phe Ser Ile
                 995                1000                1005

 Asn Ser Gly Lys Lys Met Thr Thr Ser Thr Asp His Leu Lys Arg
                1010                1015                1020

 Gly Thr Ile Leu Asp Cys Asn Thr Cys Lys Phe Ala Thr Ile Thr
                1025                1030                1035

 Cys Asn Leu Thr Ser Ser Asp Ile Ser Gln Val Asn Val Ser Leu
                1040                1045                1050

 Ile Leu Trp Lys Pro Thr Phe Ile Lys Ser Tyr Phe Ser Ser Leu
                1055                1060                1065

 Asn Leu Thr Ile Arg Gly Glu Leu Arg Ser Glu Asn Ala Ser Leu
                1070                1075                1080

 Val Leu Ser Ser Ser Asn Gln Lys Arg Glu Leu Ala Ile Gln Ile
                1085                1090                1095

 Ser Lys Asp Gly Leu Pro Gly Arg Val Pro Leu Trp Val Ile Leu
                1100                1105                1110

 Leu Ser Ala Phe Ala Gly Leu Leu Leu Leu Met Leu Leu Ile Leu
                1115                1120                1125

 Ala Leu Trp Lys Ile Gly Phe Phe Lys Arg Pro Leu Lys Lys Lys
                1130                1135                1140

 Met Glu Lys


<210> 5918
<211> 1578
<212> DNA
<213> Homo sapien

<400> 5918
 acgaacaggc caataaggag ggagcagtgc ggggtttaaa tctgaggcta 50

 ggctggctct tctcggcgtg ctgcggcgga acggctgttg gtttctgctg 100

 gttgtaggtc cttggctggt cgggcctccg gtgttctgct tctccccgct 150

 gagctgctgc ctggtgaaga ggaagccatg gcgctccgag tcaccaggaa 200

 ctcgaaaatt aatgctgaaa ataaggcgaa gatcaacatg gcaggcgcaa 250

 agcgcgttcc tacggcccct gctgcaacct ccaagcccgg actgaggcca 300

 agaacagctc ttggggacat tggtaacaaa gtcagtgaac aactgcaggc 350

 caaaatgcct atgaagaagg aagcaaaacc ttcagctact ggaaaagtca 400

 ttgataaaaa actaccaaaa cctcttgaaa aggtacctat gctggtgcca 450

 gtgccagtgt ctgagccagt gccagagcca gaacctgagc cagaacctga 500

 gcctgttaaa gaagaaaaac tttcgcctga gcctattttg gttgatactg 550

 cctctccaag cccaatggaa acatctggat gtgcccctgc agaagaagac 600

 ctgtgtcagg ctttctctga tgtaattctt gcagtaaatg atgtggatgc 650

 agaagatgga gctgatccaa acctttgtag tgaatatgtg aaagatattt 700

 atgcttatct gagacaactt gaggaagagc aagcagtcag accaaaatac 750

 ctactgggtc gggaagtcac tggaaacatg agagccatcc taattgactg 800

 gctagtacag gttcaaatga aattcaggtt gttgcaggag accatgtaca 850

 tgactgtctc cattattgat cggttcatgc agaataattg tgtgcccaag 900

 aagatgctgc agctggttgg tgtcactgcc atgtttattg caagcaaata 950

 tgaagaaatg taccctccag aaattggtga ctttgctttt gtgactgaca 1000

 acacttatac taagcaccaa atcagacaga tggaaatgaa gattctaaga 1050

 gctttaaact ttggtctggg tcggcctcta cctttgcact tccttcggag 1100

 agcatctaag attggagagg ttgatgtcga gcaacatact ttggccaaat 1150

 acctgatgga actaactatg ttggactatg acatggtgca ctttcctcct 1200

 tctcaaattg cagcaggagc tttttgctta gcactgaaaa ttctggataa 1250

 tggtgaatgg acaccaactc tacaacatta cctgtcatat actgaagaat 1300

 ctcttcttcc agttatgcag cacctggcta agaatgtagt catggtaaat 1350

 caaggactta caaagcacat gactgtcaag aacaagtatg ccacatcgaa 1400

 gcatgctaag atcagcactc taccacagct gaattctgca ctagttcaag 1450

 atttagccaa ggctgtggca aaggtgtaac ttgtaaactt gagttggagt 1500

 actatattta caaataaaat tggcaccatg tgccatctgt aaaaaaaaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaa 1578

<210> 5919
<211> 433
<212> PRT
<213> Homo sapien

<400> 5919
 Met Ala Leu Arg Val Thr Arg Asn Ser Lys Ile Asn Ala Glu Asn
   1               5                  10                  15

 Lys Ala Lys Ile Asn Met Ala Gly Ala Lys Arg Val Pro Thr Ala
                  20                  25                  30

 Pro Ala Ala Thr Ser Lys Pro Gly Leu Arg Pro Arg Thr Ala Leu
                  35                  40                  45

 Gly Asp Ile Gly Asn Lys Val Ser Glu Gln Leu Gln Ala Lys Met
                  50                  55                  60

 Pro Met Lys Lys Glu Ala Lys Pro Ser Ala Thr Gly Lys Val Ile
                  65                  70                  75

 Asp Lys Lys Leu Pro Lys Pro Leu Glu Lys Val Pro Met Leu Val
                  80                  85                  90

 Pro Val Pro Val Ser Glu Pro Val Pro Glu Pro Glu Pro Glu Pro
                  95                 100                 105

 Glu Pro Glu Pro Val Lys Glu Glu Lys Leu Ser Pro Glu Pro Ile
                 110                 115                 120

 Leu Val Asp Thr Ala Ser Pro Ser Pro Met Glu Thr Ser Gly Cys
                 125                 130                 135

 Ala Pro Ala Glu Glu Asp Leu Cys Gln Ala Phe Ser Asp Val Ile
                 140                 145                 150

 Leu Ala Val Asn Asp Val Asp Ala Glu Asp Gly Ala Asp Pro Asn
                 155                 160                 165

 Leu Cys Ser Glu Tyr Val Lys Asp Ile Tyr Ala Tyr Leu Arg Gln
                 170                 175                 180

 Leu Glu Glu Glu Gln Ala Val Arg Pro Lys Tyr Leu Leu Gly Arg
                 185                 190                 195

 Glu Val Thr Gly Asn Met Arg Ala Ile Leu Ile Asp Trp Leu Val
                 200                 205                 210

 Gln Val Gln Met Lys Phe Arg Leu Leu Gln Glu Thr Met Tyr Met
                 215                 220                 225

 Thr Val Ser Ile Ile Asp Arg Phe Met Gln Asn Asn Cys Val Pro
                 230                 235                 240

 Lys Lys Met Leu Gln Leu Val Gly Val Thr Ala Met Phe Ile Ala
                 245                 250                 255

 Ser Lys Tyr Glu Glu Met Tyr Pro Pro Glu Ile Gly Asp Phe Ala
                 260                 265                 270

 Phe Val Thr Asp Asn Thr Tyr Thr Lys His Gln Ile Arg Gln Met
                 275                 280                 285

 Glu Met Lys Ile Leu Arg Ala Leu Asn Phe Gly Leu Gly Arg Pro
                 290                 295                 300

 Leu Pro Leu His Phe Leu Arg Arg Ala Ser Lys Ile Gly Glu Val
                 305                 310                 315

 Asp Val Glu Gln His Thr Leu Ala Lys Tyr Leu Met Glu Leu Thr
                 320                 325                 330

 Met Leu Asp Tyr Asp Met Val His Phe Pro Pro Ser Gln Ile Ala
                 335                 340                 345

 Ala Gly Ala Phe Cys Leu Ala Leu Lys Ile Leu Asp Asn Gly Glu
                 350                 355                 360

 Trp Thr Pro Thr Leu Gln His Tyr Leu Ser Tyr Thr Glu Glu Ser
                 365                 370                 375

 Leu Leu Pro Val Met Gln His Leu Ala Lys Asn Val Val Met Val
                 380                 385                 390

 Asn Gln Gly Leu Thr Lys His Met Thr Val Lys Asn Lys Tyr Ala
                 395                 400                 405

 Thr Ser Lys His Ala Lys Ile Ser Thr Leu Pro Gln Leu Asn Ser
                 410                 415                 420

 Ala Leu Val Gln Asp Leu Ala Lys Ala Val Ala Lys Val
                 425                 430

<210> 5920
<211> 4643
<212> DNA
<213> Homo sapien

<400> 5920
 cctactctat tcagatattc tccagattcc taaagattag agatcatttc 50

 tcattctcct aggagtactc acttcaggaa gcaaccagat aaaagagagg 100

 tgcaacggaa gccagaacat tcctcctgga aattcaacct gtttcgcagt 150

 ttctcgagga atcagcattc agtcaatccg ggccgggagc agtcatctgt 200

 ggtgaggctg attggctggg caggaacagc gccggggcgt gggctgagca 250

 cagcgcttcg ctctctttgc cacaggaagc ctgagctcat tcgagtagcg 300

 gctcttccaa gctcaaagaa gcagaggccg ctgttcgttt cctttaggtc 350

 tttccactaa agtcggagta tcttcttcca agatttcacg tcttggtggc 400

 cgttccaagg agcgcgaggt cgggatggat cttgaagggg accgcaatgg 450

 aggagcaaag aagaagaact tttttaaact gaacaataaa agtgaaaaag 500

 ataagaagga aaagaaacca actgtcagtg tattttcaat gtttcgctat 550

 tcaaattggc ttgacaagtt gtatatggtg gtgggaactt tggctgccat 600

 catccatggg gctggacttc ctctcatgat gctggtgttt ggagaaatga 650

 cagatatctt tgcaaatgca ggaaatttag aagatctgat gtcaaacatc 700

 actaatagaa gtgatatcaa tgatacaggg ttcttcatga atctggagga 750

 agacatgacc aggtatgcct attattacag tggaattggt gctggggtgc 800

 tggttgctgc ttacattcag gtttcatttt ggtgcctggc agctggaaga 850

 caaatacaca aaattagaaa acagtttttt catgctataa tgcgacagga 900

 gataggctgg tttgatgtgc acgatgttgg ggagcttaac acccgactta 950

 cagatgatgt ctccaagatt aatgaaggaa ttggtgacaa aattggaatg 1000

 ttctttcagt caatggcaac atttttcact gggtttatag taggatttac 1050

 acgtggttgg aagctaaccc ttgtgatttt ggccatcagt cctgttcttg 1100

 gactgtcagc tgctgtctgg gcaaagatac tatcttcatt tactgataaa 1150

 gaactcttag cgtatgcaaa agctggagca gtagctgaag aggtcttggc 1200

 agcaattaga actgtgattg catttggagg acaaaagaaa gaacttgaaa 1250

 ggtacaacaa aaatttagaa gaagctaaaa gaattgggat aaagaaagct 1300

 attacagcca atatttctat aggtgctgct ttcctgctga tctatgcatc 1350

 ttatgctctg gccttctggt atgggaccac cttggtcctc tcaggggaat 1400

 attctattgg acaagtactc actgtatttt ctgtattaat tggggctttt 1450

 agtgttggac aggcatctcc aagcattgaa gcatttgcaa atgcaagagg 1500

 agcagcttat gaaatcttca agataattga taataagcca agtattgaca 1550

 gctattcgaa gagtgggcac aaaccagata atattaaggg aaatttggaa 1600

 ttcagaaatg ttcacttcag ttacccatct cgaaaagaag ttaagatctt 1650

 gaagggtctg aacctgaagg tgcagagtgg gcagacggtg gccctggttg 1700

 gaaacagtgg ctgtgggaag agcacaacag tccagctgat gcagaggctc 1750

 tatgacccca cagaggggat ggtcagtgtt gatggacagg atattaggac 1800

 cataaatgta aggtttctac gggaaatcat tggtgtggtg agtcaggaac 1850

 ctgtattgtt tgccaccacg atagctgaaa acattcgcta tggccgtgaa 1900

 aatgtcacca tggatgagat tgagaaagct gtcaaggaag ccaatgccta 1950

 tgactttatc atgaaactgc ctcataaatt tgacaccctg gttggagaga 2000

 gaggggccca gttgagtggt gggcagaagc agaggatcgc cattgcacgt 2050

 gccctggttc gcaaccccaa gatcctcctg ctggatgagg ccacgtcagc 2100

 cttggacaca gaaagcgaag cagtggttca ggtggctctg gataaggcca 2150

 gaaaaggtcg gaccaccatt gtgatagctc atcgtttgtc tacagttcgt 2200

 aatgctgacg tcatcgctgg tttcgatgat ggagtcattg tggagaaagg 2250

 aaatcatgat gaactcatga aagagaaagg catttacttc aaacttgtca 2300

 caatgcagac agcaggaaat gaagttgaat tagaaaatgc agctgatgaa 2350

 tccaaaagtg aaattgatgc cttggaaatg tcttcaaatg attcaagatc 2400

 cagtctaata agaaaaagat caactcgtag gagtgtccgt ggatcacaag 2450

 cccaagacag aaagcttagt accaaagagg ctctggatga aagtatacct 2500

 ccagtttcct tttggaggat tatgaagcta aatttaactg aatggcctta 2550

 ttttgttgtt ggtgtatttt gtgccattat aaatggaggc ctgcaaccag 2600

 catttgcaat aatattttca aagattatag gggtttttac aagaattgat 2650

 gatcctgaaa caaaacgaca gaatagtaac ttgttttcac tattgtttct 2700

 agcccttgga attatttctt ttattacatt tttccttcag ggtttcacat 2750

 ttggcaaagc tggagagatc ctcaccaagc ggctccgata catggttttc 2800

 cgatccatgc tcagacagga tgtgagttgg tttgatgacc ctaaaaacac 2850

 cactggagca ttgactacca ggctcgccaa tgatgctgct caagttaaag 2900

 gggctatagg ttccaggctt gctgtaatta cccagaatat agcaaatctt 2950

 gggacaggaa taattatatc cttcatctat ggttggcaac taacactgtt 3000

 actcttagca attgtaccca tcattgcaat agcaggagtt gttgaaatga 3050

 aaatgttgtc tggacaagca ctgaaagata agaaagaact agaaggtgct 3100

 gggaagatcg ctactgaagc aatagaaaac ttccgaaccg ttgtttcttt 3150

 gactcaggag cagaagtttg aacatatgta tgctcagagt ttgcaggtac 3200

 catacagaaa ctctttgagg aaagcacaca tctttggaat tacattttcc 3250

 ttcacccagg caatgatgta tttttcctat gctggatgtt tccggtttgg 3300

 agcctacttg gtggcacata aactcatgag ctttgaggat gttctgttag 3350

 tattttcagc tgttgtcttt ggtgccatgg ccgtggggca agtcagttca 3400

 tttgctcctg actatgccaa agccaaaata tcagcagccc acatcatcat 3450

 gatcattgaa aaaacccctt tgattgacag ctacagcacg gaaggcctaa 3500

 tgccgaacac attggaagga aatgtcacat ttggtgaagt tgtattcaac 3550

 tatcccaccc gaccggacat cccagtgctt cagggactga gcctggaggt 3600

 gaagaagggc cagacgctgg ctctggtggg cagcagtggc tgtgggaaga 3650

 gcacagtggt ccagctcctg gagcggttct acgacccctt ggcagggaaa 3700

 gtgctgcttg atggcaaaga aataaagcga ctgaatgttc agtggctccg 3750

 agcacacctg ggcatcgtgt cccaggagcc catcctgttt gactgcagca 3800

 ttgctgagaa cattgcctat ggagacaaca gccgggtggt gtcacaggaa 3850

 gagattgtga gggcagcaaa ggaggccaac atacatgcct tcatcgagtc 3900

 actgcctaat aaatatagca ctaaagtagg agacaaagga actcagctct 3950

 ctggtggcca gaaacaacgc attgccatag ctcgtgccct tgttagacag 4000

 cctcatattt tgcttttgga tgaagccacg tcagctctgg atacagaaag 4050

 tgaaaaggtt gtccaagaag ccctggacaa agccagagaa ggccgcacct 4100

 gcattgtgat tgctcaccgc ctgtccacca tccagaatgc agacttaata 4150

 gtggtgtttc agaatggcag agtcaaggag catggcacgc atcagcagct 4200

 gctggcacag aaaggcatct atttttcaat ggtcagtgtc caggctggaa 4250

 caaagcgcca gtgaactctg actgtatgag atgttaaata ctttttaata 4300

 tttgtttaga tatgacattt attcaaagtt aaaagcaaac acttacagaa 4350

 ttatgaagag gtatctgttt aacatttcct cagtcaagtt cagagtcttc 4400

 agagacttcg taattaaagg aacagagtga gagacatcat caagtggaga 4450

 gaaatcatag tttaaactgc attataaatt ttataacaga attaaagtag 4500

 attttaaaag ataaaatgtg taattttgtt tatattttcc catttggact 4550

 gtaactgact gccttgctaa aagattatag aagtagcaaa aagtattgaa 4600

 atgtttgcat aaagtgtcta taataaaact aaactttcat gtg 4643

<210> 5921
<211> 1279
<212> PRT
<213> Homo sapien

<400> 5921
 Met Asp Leu Glu Gly Asp Arg Asn Gly Gly Ala Lys Lys Lys Asn
   1               5                  10                  15

 Phe Phe Lys Leu Asn Asn Lys Ser Glu Lys Asp Lys Lys Glu Lys
                  20                  25                  30

 Lys Pro Thr Val Ser Val Phe Ser Met Phe Arg Tyr Ser Asn Trp
                  35                  40                  45

 Leu Asp Lys Leu Tyr Met Val Val Gly Thr Leu Ala Ala Ile Ile
                  50                  55                  60

 His Gly Ala Gly Leu Pro Leu Met Met Leu Val Phe Gly Glu Met
                  65                  70                  75

 Thr Asp Ile Phe Ala Asn Ala Gly Asn Leu Glu Asp Leu Met Ser
                  80                  85                  90

 Asn Ile Thr Asn Arg Ser Asp Ile Asn Asp Thr Gly Phe Phe Met
                  95                 100                 105

 Asn Leu Glu Glu Asp Met Thr Arg Tyr Ala Tyr Tyr Tyr Ser Gly
                 110                 115                 120

 Ile Gly Ala Gly Val Leu Val Ala Ala Tyr Ile Gln Val Ser Phe
                 125                 130                 135

 Trp Cys Leu Ala Ala Gly Arg Gln Ile His Lys Ile Arg Lys Gln
                 140                 145                 150

 Phe Phe His Ala Ile Met Arg Gln Glu Ile Gly Trp Phe Asp Val
                 155                 160                 165

 His Asp Val Gly Glu Leu Asn Thr Arg Leu Thr Asp Asp Val Ser
                 170                 175                 180

 Lys Ile Asn Glu Gly Ile Gly Asp Lys Ile Gly Met Phe Phe Gln
                 185                 190                 195

 Ser Met Ala Thr Phe Phe Thr Gly Phe Ile Val Gly Phe Thr Arg
                 200                 205                 210

 Gly Trp Lys Leu Thr Leu Val Ile Leu Ala Ile Ser Pro Val Leu
                 215                 220                 225

 Gly Leu Ser Ala Ala Val Trp Ala Lys Ile Leu Ser Ser Phe Thr
                 230                 235                 240

 Asp Lys Glu Leu Leu Ala Tyr Ala Lys Ala Gly Ala Val Ala Glu
                 245                 250                 255

 Glu Val Leu Ala Ala Ile Arg Thr Val Ile Ala Phe Gly Gly Gln
                 260                 265                 270

 Lys Lys Glu Leu Glu Arg Tyr Asn Lys Asn Leu Glu Glu Ala Lys
                 275                 280                 285

 Arg Ile Gly Ile Lys Lys Ala Ile Thr Ala Asn Ile Ser Ile Gly
                 290                 295                 300

 Ala Ala Phe Leu Leu Ile Tyr Ala Ser Tyr Ala Leu Ala Phe Trp
                 305                 310                 315

 Tyr Gly Thr Thr Leu Val Leu Ser Gly Glu Tyr Ser Ile Gly Gln
                 320                 325                 330

 Val Leu Thr Val Phe Ser Val Leu Ile Gly Ala Phe Ser Val Gly
                 335                 340                 345

 Gln Ala Ser Pro Ser Ile Glu Ala Phe Ala Asn Ala Arg Gly Ala
                 350                 355                 360

 Ala Tyr Glu Ile Phe Lys Ile Ile Asp Asn Lys Pro Ser Ile Asp
                 365                 370                 375

 Ser Tyr Ser Lys Ser Gly His Lys Pro Asp Asn Ile Lys Gly Asn
                 380                 385                 390

 Leu Glu Phe Arg Asn Val His Phe Ser Tyr Pro Ser Arg Lys Glu
                 395                 400                 405

 Val Lys Ile Leu Lys Gly Leu Asn Leu Lys Val Gln Ser Gly Gln
                 410                 415                 420

 Thr Val Ala Leu Val Gly Asn Ser Gly Cys Gly Lys Ser Thr Thr
                 425                 430                 435

 Val Gln Leu Met Gln Arg Leu Tyr Asp Pro Thr Glu Gly Met Val
                 440                 445                 450

 Ser Val Asp Gly Gln Asp Ile Arg Thr Ile Asn Val Arg Phe Leu
                 455                 460                 465

 Arg Glu Ile Ile Gly Val Val Ser Gln Glu Pro Val Leu Phe Ala
                 470                 475                 480

 Thr Thr Ile Ala Glu Asn Ile Arg Tyr Gly Arg Glu Asn Val Thr
                 485                 490                 495

 Met Asp Glu Ile Glu Lys Ala Val Lys Glu Ala Asn Ala Tyr Asp
                 500                 505                 510

 Phe Ile Met Lys Leu Pro His Lys Phe Asp Thr Leu Val Gly Glu
                 515                 520                 525

 Arg Gly Ala Gln Leu Ser Gly Gly Gln Lys Gln Arg Ile Ala Ile
                 530                 535                 540

 Ala Arg Ala Leu Val Arg Asn Pro Lys Ile Leu Leu Leu Asp Glu
                 545                 550                 555

 Ala Thr Ser Ala Leu Asp Thr Glu Ser Glu Ala Val Val Gln Val
                 560                 565                 570

 Ala Leu Asp Lys Ala Arg Lys Gly Arg Thr Thr Ile Val Ile Ala
                 575                 580                 585

 His Arg Leu Ser Thr Val Arg Asn Ala Asp Val Ile Ala Gly Phe
                 590                 595                 600

 Asp Asp Gly Val Ile Val Glu Lys Gly Asn His Asp Glu Leu Met
                 605                 610                 615

 Lys Glu Lys Gly Ile Tyr Phe Lys Leu Val Thr Met Gln Thr Ala
                 620                 625                 630

 Gly Asn Glu Val Glu Leu Glu Asn Ala Ala Asp Glu Ser Lys Ser
                 635                 640                 645

 Glu Ile Asp Ala Leu Glu Met Ser Ser Asn Asp Ser Arg Ser Ser
                 650                 655                 660

 Leu Ile Arg Lys Arg Ser Thr Arg Arg Ser Val Arg Gly Ser Gln
                 665                 670                 675

 Ala Gln Asp Arg Lys Leu Ser Thr Lys Glu Ala Leu Asp Glu Ser
                 680                 685                 690

 Ile Pro Pro Val Ser Phe Trp Arg Ile Met Lys Leu Asn Leu Thr
                 695                 700                 705

 Glu Trp Pro Tyr Phe Val Val Gly Val Phe Cys Ala Ile Ile Asn
                 710                 715                 720

 Gly Gly Leu Gln Pro Ala Phe Ala Ile Ile Phe Ser Lys Ile Ile
                 725                 730                 735

 Gly Val Phe Thr Arg Ile Asp Asp Pro Glu Thr Lys Arg Gln Asn
                 740                 745                 750

 Ser Asn Leu Phe Ser Leu Leu Phe Leu Ala Leu Gly Ile Ile Ser
                 755                 760                 765

 Phe Ile Thr Phe Phe Leu Gln Gly Phe Thr Phe Gly Lys Ala Gly
                 770                 775                 780

 Glu Ile Leu Thr Lys Arg Leu Arg Tyr Met Val Phe Arg Ser Met
                 785                 790                 795

 Leu Arg Gln Asp Val Ser Trp Phe Asp Asp Pro Lys Asn Thr Thr
                 800                 805                 810

 Gly Ala Leu Thr Thr Arg Leu Ala Asn Asp Ala Ala Gln Val Lys
                 815                 820                 825

 Gly Ala Ile Gly Ser Arg Leu Ala Val Ile Thr Gln Asn Ile Ala
                 830                 835                 840

 Asn Leu Gly Thr Gly Ile Ile Ile Ser Phe Ile Tyr Gly Trp Gln
                 845                 850                 855

 Leu Thr Leu Leu Leu Leu Ala Ile Val Pro Ile Ile Ala Ile Ala
                 860                 865                 870

 Gly Val Val Glu Met Lys Met Leu Ser Gly Gln Ala Leu Lys Asp
                 875                 880                 885

 Lys Lys Glu Leu Glu Gly Ala Gly Lys Ile Ala Thr Glu Ala Ile
                 890                 895                 900

 Glu Asn Phe Arg Thr Val Val Ser Leu Thr Gln Glu Gln Lys Phe
                 905                 910                 915

 Glu His Met Tyr Ala Gln Ser Leu Gln Val Pro Tyr Arg Asn Ser
                 920                 925                 930

 Leu Arg Lys Ala His Ile Phe Gly Ile Thr Phe Ser Phe Thr Gln
                 935                 940                 945

 Ala Met Met Tyr Phe Ser Tyr Ala Gly Cys Phe Arg Phe Gly Ala
                 950                 955                 960

 Tyr Leu Val Ala His Lys Leu Met Ser Phe Glu Asp Val Leu Leu
                 965                 970                 975

 Val Phe Ser Ala Val Val Phe Gly Ala Met Ala Val Gly Gln Val
                 980                 985                 990

 Ser Ser Phe Ala Pro Asp Tyr Ala Lys Ala Lys Ile Ser Ala Ala
                 995                1000                1005

 His Ile Ile Met Ile Ile Glu Lys Thr Pro Leu Ile Asp Ser Tyr
                1010                1015                1020

 Ser Thr Glu Gly Leu Met Pro Asn Thr Leu Glu Gly Asn Val Thr
                1025                1030                1035

 Phe Gly Glu Val Val Phe Asn Tyr Pro Thr Arg Pro Asp Ile Pro
                1040                1045                1050

 Val Leu Gln Gly Leu Ser Leu Glu Val Lys Lys Gly Gln Thr Leu
                1055                1060                1065

 Ala Leu Val Gly Ser Ser Gly Cys Gly Lys Ser Thr Val Val Gln
                1070                1075                1080

 Leu Leu Glu Arg Phe Tyr Asp Pro Leu Ala Gly Lys Val Leu Leu
                1085                1090                1095

 Asp Gly Lys Glu Ile Lys Arg Leu Asn Val Gln Trp Leu Arg Ala
                1100                1105                1110

 His Leu Gly Ile Val Ser Gln Glu Pro Ile Leu Phe Asp Cys Ser
                1115                1120                1125

 Ile Ala Glu Asn Ile Ala Tyr Gly Asp Asn Ser Arg Val Val Ser
                1130                1135                1140

 Gln Glu Glu Ile Val Arg Ala Ala Lys Glu Ala Asn Ile His Ala
                1145                1150                1155

 Phe Ile Glu Ser Leu Pro Asn Lys Tyr Ser Thr Lys Val Gly Asp
                1160                1165                1170

 Lys Gly Thr Gln Leu Ser Gly Gly Gln Lys Gln Arg Ile Ala Ile
                1175                1180                1185

 Ala Arg Ala Leu Val Arg Gln Pro His Ile Leu Leu Leu Asp Glu
                1190                1195                1200

 Ala Thr Ser Ala Leu Asp Thr Glu Ser Glu Lys Val Val Gln Glu
                1205                1210                1215

 Ala Leu Asp Lys Ala Arg Glu Gly Arg Thr Cys Ile Val Ile Ala
                1220                1225                1230

 His Arg Leu Ser Thr Ile Gln Asn Ala Asp Leu Ile Val Val Phe
                1235                1240                1245

 Gln Asn Gly Arg Val Lys Glu His Gly Thr His Gln Gln Leu Leu
                1250                1255                1260

 Ala Gln Lys Gly Ile Tyr Phe Ser Met Val Ser Val Gln Ala Gly
                1265                1270                1275

 Thr Lys Arg Gln


<210> 5922
<211> 3493
<212> DNA
<213> Homo sapien

<400> 5922
 agcggccggg gccacgatgg agcgcgacgg ctgcgcgggg ggcgggagcc 50

 gcggcggcga gggcgggcgc gctccccggg agggcccggc ggggaacggc 100

 cgcgatcggg gccgcagcca cgctgccgag gcgcccgggg acccgcaggc 150

 ggccgcgtcc ttgctggccc ctatggacgt gggggaggag ccgctggaga 200

 aggcggcgcg cgcccgcact gccaaggacc ccaacaccta taaagtactc 250

 tcgctggtat tgtcagtatg tgtgttaaca acaatacttg gttgtatatt 300

 tgggttgaaa ccaagctgtg ccaaagaagt taaaagttgc aaaggtcgct 350

 gtttcgagag aacatttggg aactgtcgct gtgatgctgc ctgtgttgag 400

 cttggaaact gctgtttaga ttaccaggag acgtgcatag aaccagaaca 450

 tatatggact tgcaacaaat tcaggtgtgg tgagaaaagg ttgaccagaa 500

 gcctctgtgc ctgttcagat gactgcaagg acaagggcga ctgctgcatc 550

 aactacagtt ctgtgtgtca aggtgagaaa agttgggtag aagaaccatg 600

 tgagagcatt aatgagccac agtgcccagc agggtttgaa acgcctccta 650

 ccctcttatt ttctttggat ggattcaggg cagaatattt acacacttgg 700

 ggtggacttc ttcctgttat tagcaaacta aaaaaatgtg gaacatatac 750

 taaaaacatg agaccggtat atccaacaaa aactttcccc aatcactaca 800

 gcattgtcac cggattgtat ccagaatctc atggcataat cgacaataaa 850

 atgtatgatc ccaaaatgaa tgcttccttt tcacttaaaa gtaaagagaa 900

 atttaatcct gagtggtaca aaggagaacc aatttgggtc acagctaagt 950

 atcaaggcct caagtctggc acatttttct ggccaggatc agatgtggaa 1000

 attaacggaa ttttcccaga catctataaa atgtataatg gttcagtacc 1050

 atttgaagaa aggattttag ctgttcttca gtggctacag cttcctaaag 1100

 atgaaagacc acacttttac actctgtatt tagaagaacc agattcttca 1150

 ggtcattcat atggaccagt cagcagtgaa gtcatcaaag ccttgcagag 1200

 ggttgatggt atggttggta tgctgatgga tggtctgaaa gagctgaact 1250

 tgcacagatg cctgaacctc atccttattt cagatcatgg catggaacaa 1300

 ggcagttgta agaaatacat atatctgaat aaatatttgg gggatgttaa 1350

 aaatattaaa gttatctatg gacctgcagc tcgattgaga ccctctgatg 1400

 tcccagataa atactattca tttaactatg aaggcattgc ccgaaatctt 1450

 tcttgccggg aaccaaacca gcacttcaaa ccttacctga aacatttctt 1500

 acctaagcgt ttgcactttg ctaagagtga tagaattgag cccttgacat 1550

 tctatttgga ccctcagtgg caacttgcat tgaatccctc agaaaggaaa 1600

 tattgtggaa gtggatttca tggctctgac aatgtatttt caaatatgca 1650

 agccctcttt gttggctatg gacctggatt caagcatggc attgaggctg 1700

 acacctttga aaacattgaa gtctataact taatgtgtga tttactgaat 1750

 ttgacaccgg ctcctaataa cggaactcat ggaagtctta accaccttct 1800

 aaagaatcct gtttatacgc caaagcatcc caaagaagtg caccccctgg 1850

 tacagtgccc cttcacaaga aaccccagag ataaccttgg ctgctcatgt 1900

 aacccttcga ttttgccgat tgaggatttt caaacacagt tcaatctgac 1950

 tgtggcagaa gagaagatta ttaagcatga aactttaccc tatggaagac 2000

 ctagagttct ccagaaggaa aacaccatct gtcttctttc ccagcaccag 2050

 tttatgagtg gatacagcca agacatctta atgccccttt ggacatccta 2100

 taccgtggac agaaatgaca gtttctctac ggaagacttc tccaactgtc 2150

 tgtaccagga ctttagaatt cctcttagtc ctgtccataa atgttcattt 2200

 tataaaaata acaccaaagt gagttacggg ttcctctccc caccacaact 2250

 aaataaaaat tcaagtggaa tatattctga agctttgctt actacaaata 2300

 tagtgccaat gtaccagagt tttcaagtta tatggcgcta ctttcatgac 2350

 accctactgc gaaagtatgc tgaagaaaga aatggtgtca atgtcgtcag 2400

 tggtcctgtg tttgactttg attatgatgg acgttgtgat tccttagaga 2450

 atctgaggca aaaaagaaga gtcatccgta accaagaaat tttgattcca 2500

 actcacttct ttattgtgct aacaagctgt aaagatacat ctcagacgcc 2550

 tttgcactgt gaaaacctag acaccttagc tttcattttg cctcacagga 2600

 ctgataacag cgagagctgt gtgcatggga agcatgactc ctcatgggtt 2650

 gaagaattgt taatgttaca cagagcacgg atcacagatg ttgagcacat 2700

 cactggactc agcttctatc aacaaagaaa agagccagtt tcagacattt 2750

 taaagttgaa aacacatttg ccaaccttta gccaagaaga ctgatatgtt 2800

 ttttatcccc aaacaccatg aatctttttg agagaacctt atattttata 2850

 tagtcctcta gctacactat tgcattgttc agaaactgtc gaccagagtt 2900

 agaacggagc cctcggtgat gcggacatct cagggaaact tgcgtactca 2950

 gcacagcagt ggagagtgtt cctgttgaat cttgcacata tttgaatgtg 3000

 taagcattgt atacattgat caagttcggg ggaataaaga cagaccacac 3050

 ctaaaactgc ctttctgctt ctcttaaagg agaagtagct gtgaacattg 3100

 tctggatacc agatatttga atctttctta ctattggtaa taaaccttga 3150

 tggcattggg caaacagtag acttatagta gggttggggt agcccatgtt 3200

 atgtgactat ctttatgaga attttaaagt ggttctggat atcttttaac 3250

 ttggagtttc atttcttttc attgtaatca aaaaaaaaat taacagaagc 3300

 caaaatactt ctgagacctt gtttcaatct ttgctgtata tcccctcaaa 3350

 atccaagtta ttaatcttat gtgttttctt tttaattttt tgattggatt 3400

 tctttagatt taatggttca aatgagttca actttgaggg acgatctttg 3450

 aatatactta cctattataa aatcttactt tgtatttgta ttt 3493

<210> 5923
<211> 873
<212> PRT
<213> Homo sapien

<400> 5923
 Met Asp Val Gly Glu Glu Pro Leu Glu Lys Ala Ala Arg Ala Arg
   1               5                  10                  15

 Thr Ala Lys Asp Pro Asn Thr Tyr Lys Val Leu Ser Leu Val Leu
                  20                  25                  30

 Ser Val Cys Val Leu Thr Thr Ile Leu Gly Cys Ile Phe Gly Leu
                  35                  40                  45

 Lys Pro Ser Cys Ala Lys Glu Val Lys Ser Cys Lys Gly Arg Cys
                  50                  55                  60

 Phe Glu Arg Thr Phe Gly Asn Cys Arg Cys Asp Ala Ala Cys Val
                  65                  70                  75

 Glu Leu Gly Asn Cys Cys Leu Asp Tyr Gln Glu Thr Cys Ile Glu
                  80                  85                  90

 Pro Glu His Ile Trp Thr Cys Asn Lys Phe Arg Cys Gly Glu Lys
                  95                 100                 105

 Arg Leu Thr Arg Ser Leu Cys Ala Cys Ser Asp Asp Cys Lys Asp
                 110                 115                 120

 Lys Gly Asp Cys Cys Ile Asn Tyr Ser Ser Val Cys Gln Gly Glu
                 125                 130                 135

 Lys Ser Trp Val Glu Glu Pro Cys Glu Ser Ile Asn Glu Pro Gln
                 140                 145                 150

 Cys Pro Ala Gly Phe Glu Thr Pro Pro Thr Leu Leu Phe Ser Leu
                 155                 160                 165

 Asp Gly Phe Arg Ala Glu Tyr Leu His Thr Trp Gly Gly Leu Leu
                 170                 175                 180

 Pro Val Ile Ser Lys Leu Lys Lys Cys Gly Thr Tyr Thr Lys Asn
                 185                 190                 195

 Met Arg Pro Val Tyr Pro Thr Lys Thr Phe Pro Asn His Tyr Ser
                 200                 205                 210

 Ile Val Thr Gly Leu Tyr Pro Glu Ser His Gly Ile Ile Asp Asn
                 215                 220                 225

 Lys Met Tyr Asp Pro Lys Met Asn Ala Ser Phe Ser Leu Lys Ser
                 230                 235                 240

 Lys Glu Lys Phe Asn Pro Glu Trp Tyr Lys Gly Glu Pro Ile Trp
                 245                 250                 255

 Val Thr Ala Lys Tyr Gln Gly Leu Lys Ser Gly Thr Phe Phe Trp
                 260                 265                 270

 Pro Gly Ser Asp Val Glu Ile Asn Gly Ile Phe Pro Asp Ile Tyr
                 275                 280                 285

 Lys Met Tyr Asn Gly Ser Val Pro Phe Glu Glu Arg Ile Leu Ala
                 290                 295                 300

 Val Leu Gln Trp Leu Gln Leu Pro Lys Asp Glu Arg Pro His Phe
                 305                 310                 315

 Tyr Thr Leu Tyr Leu Glu Glu Pro Asp Ser Ser Gly His Ser Tyr
                 320                 325                 330

 Gly Pro Val Ser Ser Glu Val Ile Lys Ala Leu Gln Arg Val Asp
                 335                 340                 345

 Gly Met Val Gly Met Leu Met Asp Gly Leu Lys Glu Leu Asn Leu
                 350                 355                 360

 His Arg Cys Leu Asn Leu Ile Leu Ile Ser Asp His Gly Met Glu
                 365                 370                 375

 Gln Gly Ser Cys Lys Lys Tyr Ile Tyr Leu Asn Lys Tyr Leu Gly
                 380                 385                 390

 Asp Val Lys Asn Ile Lys Val Ile Tyr Gly Pro Ala Ala Arg Leu
                 395                 400                 405

 Arg Pro Ser Asp Val Pro Asp Lys Tyr Tyr Ser Phe Asn Tyr Glu
                 410                 415                 420

 Gly Ile Ala Arg Asn Leu Ser Cys Arg Glu Pro Asn Gln His Phe
                 425                 430                 435

 Lys Pro Tyr Leu Lys His Phe Leu Pro Lys Arg Leu His Phe Ala
                 440                 445                 450

 Lys Ser Asp Arg Ile Glu Pro Leu Thr Phe Tyr Leu Asp Pro Gln
                 455                 460                 465

 Trp Gln Leu Ala Leu Asn Pro Ser Glu Arg Lys Tyr Cys Gly Ser
                 470                 475                 480

 Gly Phe His Gly Ser Asp Asn Val Phe Ser Asn Met Gln Ala Leu
                 485                 490                 495

 Phe Val Gly Tyr Gly Pro Gly Phe Lys His Gly Ile Glu Ala Asp
                 500                 505                 510

 Thr Phe Glu Asn Ile Glu Val Tyr Asn Leu Met Cys Asp Leu Leu
                 515                 520                 525

 Asn Leu Thr Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn
                 530                 535                 540

 His Leu Leu Lys Asn Pro Val Tyr Thr Pro Lys His Pro Lys Glu
                 545                 550                 555

 Val His Pro Leu Val Gln Cys Pro Phe Thr Arg Asn Pro Arg Asp
                 560                 565                 570

 Asn Leu Gly Cys Ser Cys Asn Pro Ser Ile Leu Pro Ile Glu Asp
                 575                 580                 585

 Phe Gln Thr Gln Phe Asn Leu Thr Val Ala Glu Glu Lys Ile Ile
                 590                 595                 600

 Lys His Glu Thr Leu Pro Tyr Gly Arg Pro Arg Val Leu Gln Lys
                 605                 610                 615

 Glu Asn Thr Ile Cys Leu Leu Ser Gln His Gln Phe Met Ser Gly
                 620                 625                 630

 Tyr Ser Gln Asp Ile Leu Met Pro Leu Trp Thr Ser Tyr Thr Val
                 635                 640                 645

 Asp Arg Asn Asp Ser Phe Ser Thr Glu Asp Phe Ser Asn Cys Leu
                 650                 655                 660

 Tyr Gln Asp Phe Arg Ile Pro Leu Ser Pro Val His Lys Cys Ser
                 665                 670                 675

 Phe Tyr Lys Asn Asn Thr Lys Val Ser Tyr Gly Phe Leu Ser Pro
                 680                 685                 690

 Pro Gln Leu Asn Lys Asn Ser Ser Gly Ile Tyr Ser Glu Ala Leu
                 695                 700                 705

 Leu Thr Thr Asn Ile Val Pro Met Tyr Gln Ser Phe Gln Val Ile
                 710                 715                 720

 Trp Arg Tyr Phe His Asp Thr Leu Leu Arg Lys Tyr Ala Glu Glu
                 725                 730                 735

 Arg Asn Gly Val Asn Val Val Ser Gly Pro Val Phe Asp Phe Asp
                 740                 745                 750

 Tyr Asp Gly Arg Cys Asp Ser Leu Glu Asn Leu Arg Gln Lys Arg
                 755                 760                 765

 Arg Val Ile Arg Asn Gln Glu Ile Leu Ile Pro Thr His Phe Phe
                 770                 775                 780

 Ile Val Leu Thr Ser Cys Lys Asp Thr Ser Gln Thr Pro Leu His
                 785                 790                 795

 Cys Glu Asn Leu Asp Thr Leu Ala Phe Ile Leu Pro His Arg Thr
                 800                 805                 810

 Asp Asn Ser Glu Ser Cys Val His Gly Lys His Asp Ser Ser Trp
                 815                 820                 825

 Val Glu Glu Leu Leu Met Leu His Arg Ala Arg Ile Thr Asp Val
                 830                 835                 840

 Glu His Ile Thr Gly Leu Ser Phe Tyr Gln Gln Arg Lys Glu Pro
                 845                 850                 855

 Val Ser Asp Ile Leu Lys Leu Lys Thr His Leu Pro Thr Phe Ser
                 860                 865                 870

 Gln Glu Asp


<210> 5924
<211> 1150
<212> DNA
<213> Homo sapien

<400> 5924
 ttcttactgt gggctttagc tttttgtttt tctacagggg cacgctgtgt 50

 gacaaagtaa cccagagttc cccggaccag acggtggcga gtggcagtga 100

 ggtggtactg ctctgcactt acgacactgt atattcaaat ccagatttat 150

 tctggtaccg gataaggcca gattattcct ttcagtttgt cttttatggg 200

 gataacagca gatcagaagg tgcacatttt actcaaggac ggttttctgt 250

 gaaacacatt ctgacccaga aagcctttca cttggtgatc tctccagtaa 300

 ggactgaaga cagtgccact tactactgtg cctccctcaa cctaaactgg 350

 gggtctgagg acgttagctc ctgggacacc cgacagatgt ttttcggaac 400

 tggcatcaaa ctcttcgtgg agccccgaag tcagcctcat accaaaccat 450

 ccgtttttgt catgaaaaat ggaacaaatg tcgcttgtct ggtgaaggaa 500

 ttctacccca aggatataag aataaatctc gtgtcatcca agaagataac 550

 agagtttgat cctgctattg tcatctctcc cagtgggaag tacaatgctg 600

 tcaagcttgg taaatatgaa gattcaaatt cagtgacatg ttcagttcaa 650

 cacgacaata aaactgtgca ctccactgac tttgaagtga agacagattc 700

 tacagatcac gtaaaaccaa aggaaactga aaacacaaag caaccttcaa 750

 agagctgcca taaacccaaa gccatagttc ataccgagaa ggtgaacatg 800

 atgtccctca cagtgcttgg gctacgaatg ctgtttgcaa agactgttgc 850

 cgtcaatttt ctcttgactg ccaagttatt tttcttgtaa ggctgactgg 900

 catgaggaag ctacactcct gaagaaacca aaggcttaca aaaatgcatc 950

 tccttggctt ctgacttctt tgtgattcaa gttgacctgt catagccttg 1000

 ttaaaatggc tgctagccaa accacttttt cttcaaagac aacaaaccca 1050

 gctcatcctc cagcttgatg ggaagacaaa agtcctgggg aaggggggtt 1100

 tatgtcctaa ctgctttgta tgctgttttt ataaagggat agaaggatat 1150

<210> 5925
<211> 2889
<212> DNA
<213> Homo sapien

<400> 5925
 cctgtctctc ttcgggtctc gggcccttgg gcgcagcggg gcgcgcgcca 50

 tggcgaaggc gaagaaggtc ggggcgcgaa ggaaggcctc cggggcgccg 100

 gcgggagcgc gagggggccc ggcgaaggcc aactccaatc cgttcgaggt 150

 gaaagttaac aggcagaagt tccagatcct gggccggaag acgcgccacg 200

 acgtgggact gcccggggtg tctcgcgcac gggccctcag gaagcgtaca 250

 cagactttac taaaagagta caaagaaagg gataaatcca atgtattcag 300

 agataaacgc ttcggagaat acaacagcaa catgagcccc gaggagaaga 350

 tgatgaagag gtttgctctg gaacagcagc gacatcatga gaaaaaaagc 400

 atctacaatc taaatgaaga tgaagaattg actcattatg gccagtcttt 450

 ggcagacatc gagaagcata atgacattgt ggacagtgac agcgatgctg 500

 aggatcgagg aacgttgtct gctgagctga ctgctgccca ctttggagga 550

 ggcggtgggc tccttcacaa gaagactcaa caggaaggcg aggagcggga 600

 gaaaccgaag tcccggaaag agctgattga agagctcatt gccaagtcaa 650

 aacaagagaa gagggagaga caagctcaac gagaagatgc cctcgagctc 700

 acggagaagc tagaccaaga ctggaaagaa attcagactc tcctgtccca 750

 caaaactccc aagtcagaga acagagacaa aaaggaaaaa cccaagcccg 800

 atgcatatga catgatggtt cgcgagcttg gctttgaaat gaaggcgcag 850

 ccctctaaca ggatgaagac ggaggcagaa ttggcaaagg aagagcagga 900

 gcacctcagg aagctggagg ctgagagact tcgaagaatg cttggaaagg 950

 atgaggatga aaatgttaag aaaccaaaac atatgtcagc agatgatctg 1000

 aatgatggct tcgtgctaga taaagatgac aggcgtttgc tttcctacaa 1050

 agatggaaag atgaatgtcg aggaagatgt ccaggaagag caaagcaagg 1100

 aagccagtga ccctgagagc aacgaggaag aaggtgacag ttcaggcggg 1150

 gaggacacag aggagagcga cagcccagat agccacttgg acctggaatc 1200

 caacgtggag agtgaggaag aaaacgagaa gccagcaaaa gagcagaggc 1250

 agactcctgg gaaagggttg ataagcggca aggaaagagc tggaaaagct 1300

 accagagacg agctgcccta cacgttcgca gcccctgaat cctatgagga 1350

 actgagatct ctgttgttag gaagatcgat ggaagagcag cttttggtgg 1400

 tggagagaat tcagaagtgc aaccacccga gtctcgcaga aggaaacaaa 1450

 gcaaaattag aaaaactgtt tggctttctt ttggaatacg ttggcgattt 1500

 ggctacagat gacccaccag acctcacagt cattgataag ttggttgtgc 1550

 acttatatca tctttgccag atgtttcctg aatctgcaag tgacgctatc 1600

 aaatttgttc tccgagatgc gatgcatgag atggaagaaa tgattgagac 1650

 caaaggccgg gcggcattgc cagggttgga tgtgctcatt tatttgaaaa 1700

 tcactgggct gctatttcca acttccgact tctggcaccc agtggtgacc 1750

 cctgccctcg tgtgcctcag tcagctgctc accaagtgcc ccatcctgtc 1800

 cctccaggac gtggtgaagg gcctgttcgt gtgctgcctg ttcctggagt 1850

 atgtggcttt gtcccagagg tttatacctg agcttattaa ttttcttctt 1900

 gggattcttt acatagcaac tccaaacaaa gcaagccaag gttccactct 1950

 ggtgcaccct ttcagagcgc ttgggaagaa ctcggaactg ctcgtggtgt 2000

 ctgctagaga ggatgtggcc acgtggcagc agagcagcct ctccctccgc 2050

 tgggcgagta gactgagggc cccaacttcg acagaggcca atcacatccg 2100

 actgtcctgc ctggctgtgg gcctggccct gctgaagcgc tgcgtgctca 2150

 tgtacgggtc cctgccatcc ttccacgcca tcatggggcc tctccaagcc 2200

 ctcctcacgg atcacctggc ggactgcagc cacccgcagg agctccagga 2250

 gctgtgtcag agcacactga ccgaaatgga aagccagaag cagctctgcc 2300

 ggccgctgac ctgtgagaag agcaagcctg tcccactgaa gcttttcaca 2350

 ccccggctgg tcaaagtcct cgagtttgga agaaaacaag gcagtagtaa 2400

 ggaggaacag gaaaggaaga ggctgatcca caaacacaag cgtgaattta 2450

 aaggggccgt tcgagaaatc cgcaaggaca atcagttcct ggcgaggatg 2500

 caactctcag aaatcatgga acgggatgcg gaaagaaagc ggaaagtaaa 2550

 gcagcttttt aacagcctgg ctacacagga aggcgaatgg aaggctctga 2600

 agaggaaaaa gttcaaaaaa taaattacat tttataaata agctcccccc 2650

 acccgctgcc tgcggttttg tttctgttaa aacgtcacct gatgaaatag 2700

 aatgaatcct gaaatgcacc tctgggatcg ggaatggtct gtgtgttatc 2750

 agctgcgact ggttcactgc gtctggacaa gcctcatggg gactggggat 2800

 tctggccagt gtaatttctg tcaaccacgg acgtttgcct tcatgtgtag 2850

 aatttactgt tgttatgcaa attatatttt caattataa 2889

<210> 5926
<211> 873
<212> PRT
<213> Homo sapien

<400> 5926
 Leu Ser Leu Phe Gly Ser Arg Ala Leu Gly Arg Ser Gly Ala Arg
   1               5                  10                  15

 Ala Met Ala Lys Ala Lys Lys Val Gly Ala Arg Arg Lys Ala Ser
                  20                  25                  30

 Gly Ala Pro Ala Gly Ala Arg Gly Gly Pro Ala Lys Ala Asn Ser
                  35                  40                  45

 Asn Pro Phe Glu Val Lys Val Asn Arg Gln Lys Phe Gln Ile Leu
                  50                  55                  60

 Gly Arg Lys Thr Arg His Asp Val Gly Leu Pro Gly Val Ser Arg
                  65                  70                  75

 Ala Arg Ala Leu Arg Lys Arg Thr Gln Thr Leu Leu Lys Glu Tyr
                  80                  85                  90

 Lys Glu Arg Asp Lys Ser Asn Val Phe Arg Asp Lys Arg Phe Gly
                  95                 100                 105

 Glu Tyr Asn Ser Asn Met Ser Pro Glu Glu Lys Met Met Lys Arg
                 110                 115                 120

 Phe Ala Leu Glu Gln Gln Arg His His Glu Lys Lys Ser Ile Tyr
                 125                 130                 135

 Asn Leu Asn Glu Asp Glu Glu Leu Thr His Tyr Gly Gln Ser Leu
                 140                 145                 150

 Ala Asp Ile Glu Lys His Asn Asp Ile Val Asp Ser Asp Ser Asp
                 155                 160                 165

 Ala Glu Asp Arg Gly Thr Leu Ser Ala Glu Leu Thr Ala Ala His
                 170                 175                 180

 Phe Gly Gly Gly Gly Gly Leu Leu His Lys Lys Thr Gln Gln Glu
                 185                 190                 195

 Gly Glu Glu Arg Glu Lys Pro Lys Ser Arg Lys Glu Leu Ile Glu
                 200                 205                 210

 Glu Leu Ile Ala Lys Ser Lys Gln Glu Lys Arg Glu Arg Gln Ala
                 215                 220                 225

 Gln Arg Glu Asp Ala Leu Glu Leu Thr Glu Lys Leu Asp Gln Asp
                 230                 235                 240

 Trp Lys Glu Ile Gln Thr Leu Leu Ser His Lys Thr Pro Lys Ser
                 245                 250                 255

 Glu Asn Arg Asp Lys Lys Glu Lys Pro Lys Pro Asp Ala Tyr Asp
                 260                 265                 270

 Met Met Val Arg Glu Leu Gly Phe Glu Met Lys Ala Gln Pro Ser
                 275                 280                 285

 Asn Arg Met Lys Thr Glu Ala Glu Leu Ala Lys Glu Glu Gln Glu
                 290                 295                 300

 His Leu Arg Lys Leu Glu Ala Glu Arg Leu Arg Arg Met Leu Gly
                 305                 310                 315

 Lys Asp Glu Asp Glu Asn Val Lys Lys Pro Lys His Met Ser Ala
                 320                 325                 330

 Asp Asp Leu Asn Asp Gly Phe Val Leu Asp Lys Asp Asp Arg Arg
                 335                 340                 345

 Leu Leu Ser Tyr Lys Asp Gly Lys Met Asn Val Glu Glu Asp Val
                 350                 355                 360

 Gln Glu Glu Gln Ser Lys Glu Ala Ser Asp Pro Glu Ser Asn Glu
                 365                 370                 375

 Glu Glu Gly Asp Ser Ser Gly Gly Glu Asp Thr Glu Glu Ser Asp
                 380                 385                 390

 Ser Pro Asp Ser His Leu Asp Leu Glu Ser Asn Val Glu Ser Glu
                 395                 400                 405

 Glu Glu Asn Glu Lys Pro Ala Lys Glu Gln Arg Gln Thr Pro Gly
                 410                 415                 420

 Lys Gly Leu Ile Ser Gly Lys Glu Arg Ala Gly Lys Ala Thr Arg
                 425                 430                 435

 Asp Glu Leu Pro Tyr Thr Phe Ala Ala Pro Glu Ser Tyr Glu Glu
                 440                 445                 450

 Leu Arg Ser Leu Leu Leu Gly Arg Ser Met Glu Glu Gln Leu Leu
                 455                 460                 465

 Val Val Glu Arg Ile Gln Lys Cys Asn His Pro Ser Leu Ala Glu
                 470                 475                 480

 Gly Asn Lys Ala Lys Leu Glu Lys Leu Phe Gly Phe Leu Leu Glu
                 485                 490                 495

 Tyr Val Gly Asp Leu Ala Thr Asp Asp Pro Pro Asp Leu Thr Val
                 500                 505                 510

 Ile Asp Lys Leu Val Val His Leu Tyr His Leu Cys Gln Met Phe
                 515                 520                 525

 Pro Glu Ser Ala Ser Asp Ala Ile Lys Phe Val Leu Arg Asp Ala
                 530                 535                 540

 Met His Glu Met Glu Glu Met Ile Glu Thr Lys Gly Arg Ala Ala
                 545                 550                 555

 Leu Pro Gly Leu Asp Val Leu Ile Tyr Leu Lys Ile Thr Gly Leu
                 560                 565                 570

 Leu Phe Pro Thr Ser Asp Phe Trp His Pro Val Val Thr Pro Ala
                 575                 580                 585

 Leu Val Cys Leu Ser Gln Leu Leu Thr Lys Cys Pro Ile Leu Ser
                 590                 595                 600

 Leu Gln Asp Val Val Lys Gly Leu Phe Val Cys Cys Leu Phe Leu
                 605                 610                 615

 Glu Tyr Val Ala Leu Ser Gln Arg Phe Ile Pro Glu Leu Ile Asn
                 620                 625                 630

 Phe Leu Leu Gly Ile Leu Tyr Ile Ala Thr Pro Asn Lys Ala Ser
                 635                 640                 645

 Gln Gly Ser Thr Leu Val His Pro Phe Arg Ala Leu Gly Lys Asn
                 650                 655                 660

 Ser Glu Leu Leu Val Val Ser Ala Arg Glu Asp Val Ala Thr Trp
                 665                 670                 675

 Gln Gln Ser Ser Leu Ser Leu Arg Trp Ala Ser Arg Leu Arg Ala
                 680                 685                 690

 Pro Thr Ser Thr Glu Ala Asn His Ile Arg Leu Ser Cys Leu Ala
                 695                 700                 705

 Val Gly Leu Ala Leu Leu Lys Arg Cys Val Leu Met Tyr Gly Ser
                 710                 715                 720

 Leu Pro Ser Phe His Ala Ile Met Gly Pro Leu Gln Ala Leu Leu
                 725                 730                 735

 Thr Asp His Leu Ala Asp Cys Ser His Pro Gln Glu Leu Gln Glu
                 740                 745                 750

 Leu Cys Gln Ser Thr Leu Thr Glu Met Glu Ser Gln Lys Gln Leu
                 755                 760                 765

 Cys Arg Pro Leu Thr Cys Glu Lys Ser Lys Pro Val Pro Leu Lys
                 770                 775                 780

 Leu Phe Thr Pro Arg Leu Val Lys Val Leu Glu Phe Gly Arg Lys
                 785                 790                 795

 Gln Gly Ser Ser Lys Glu Glu Gln Glu Arg Lys Arg Leu Ile His
                 800                 805                 810

 Lys His Lys Arg Glu Phe Lys Gly Ala Val Arg Glu Ile Arg Lys
                 815                 820                 825

 Asp Asn Gln Phe Leu Ala Arg Met Gln Leu Ser Glu Ile Met Glu
                 830                 835                 840

 Arg Asp Ala Glu Arg Lys Arg Lys Val Lys Gln Leu Phe Asn Ser
                 845                 850                 855

 Leu Ala Thr Gln Glu Gly Glu Trp Lys Ala Leu Lys Arg Lys Lys
                 860                 865                 870

 Phe Lys Lys


<210> 5927
<211> 2486
<212> DNA
<213> Homo sapien

<400> 5927
 ccgggacttt gcaggcagcg gcggccgggg gcggagcggg atcgagccct 50

 cgccgaggcc tgccgccatg ggcccgcgcc gccgccgccg cctgtcaccc 100

 gggccgcgcg ggccgtgagc gtcatggcct tggccggggc ccctgcgggc 150

 ggcccatgcg cgccggcgct ggaggccctg ctcggggccg gcgcgctgcg 200

 gctgctcgac tcctcgcaga tcgtcatcat ctccgccgcg caggacgcca 250

 gcgccccgcc ggctcccacc ggccccgcgg cgcccgccgc cggcccctgc 300

 gaccctgacc tgctgctctt cgccacaccg caggcgcccc ggcccacacc 350

 cagtgcgccg cggcccgcgc tcggccgccc gccggtgaag cggaggctgg 400

 acctggaaac tgaccatcag tacctggccg agagcagtgg gccagctcgg 450

 ggcagaggcc gccatccagg aaaaggtgtg aaatccccgg gggagaagtc 500

 acgctatgag acctcactga atctgaccac caagcgcttc ctggagctgc 550

 tgagccactc ggctgacggt gtcgtcgacc tgaactgggc tgccgaggtg 600

 ctgaaggtgc agaagcggcg catctatgac atcaccaacg tccttgaggg 650

 catccagctc attgccaaga agtccaagaa ccacatccag tggctgggca 700

 gccacaccac agtgggcgtc ggcggacggc ttgaggggtt gacccaggac 750

 ctccgacagc tgcaggagag cgagcagcag ctggaccacc tgatgaatat 800

 ctgtactacg cagctgcgcc tgctctccga ggacactgac agccagcgcc 850

 tggcctacgt gacgtgtcag gaccttcgta gcattgcaga ccctgcagag 900

 cagatggtta tggtgatcaa agcccctcct gagacccagc tccaagccgt 950

 ggactcttcg gagaactttc agatctccct taagagcaaa caaggcccga 1000

 tcgatgtttt cctgtgccct gaggagaccg taggtgggat cagccctggg 1050

 aagaccccat cccaggaggt cacttctgag gaggagaaca gggccactga 1100

 ctctgccacc atagtgtcac caccaccatc atctcccccc tcatccctca 1150

 ccacagatcc cagccagtct ctactcagcc tggagcaaga accgctgttg 1200

 tcccggatgg gcagcctgcg ggctcccgtg gacgaggacc gcctgtcccc 1250

 gctggtggcg gccgactcgc tcctggagca tgtgcgggag gacttctccg 1300

 gcctcctccc tgaggagttc atcagccttt ccccacccca cgaggccctc 1350

 gactaccact tcggcctcga ggagggcgag ggcatcagag acctcttcga 1400

 ctgtgacttt ggggacctca cccccctgga tttctgacag ggcttggagg 1450

 gaccagggtt tccagagtag ctcaccttgt ctctgcagcc ctggagcccc 1500

 ctgtccctgg ccgtcctccc agcctgtttg gaaacattta atttataccc 1550

 ctctcctctg tctccagaag cttctagctc tggggtctgg ctaccgctag 1600

 gaggctgagc aagccaggaa gggaaggagt ctgtgtggtg tgtatgtgca 1650

 tgcagcctac acccacacgt gtgtaccggg ggtgaatgtg tgtgagcatg 1700

 tgtgtgtgca tgtaccgggg aatgaaggtg aacatacacc tctgtgtgtg 1750

 cactgcagac acgccccagt gtgtccacat gtgtgtgcat gagtccatct 1800

 ctgcgcgtgg gggggctcta actgcacttt cggccctttt gctcgtgggg 1850

 tcccacaagg cccagggcag tgcctgctcc cagaatctgg tgctctgacc 1900

 aggccaggtg gggaggcttt ggctggctgg gcgtgtagga cggtgagagc 1950

 acttctgtct taaaggtttt ttctgattga agctttaatg gagcgttatt 2000

 tatttatcga ggcctctttg gtgagcctgg ggaatcagca aaaggggagg 2050

 aggggtgtgg ggttgatacc ccaactccct ctacccttga gcaagggcag 2100

 gggtccctga gctgttcttc tgccccatac tgaaggaact gaggcctggg 2150

 tgatttattt attgggaaag tgagggaggg agacagactg actgacagcc 2200

 atgggtggtc agatggtggg gtgggccctc tccagggggc cagttcaggg 2250

 cccagctgcc ccccaggatg gatatgagat gggagaggtg agtgggggac 2300

 cttcactgat gtgggcagga ggggtggtga aggcctcccc cagcccagac 2350

 cctgtggtcc ctcctgcagt gtctgaagcg cctgcctccc cactgctctg 2400

 ccccaccctc caatctgcac tttgatttgc ttcctaacag ctctgttccc 2450

 tcctgctttg gttttaataa atattttgat gacgtt 2486

<210> 5928
<211> 437
<212> PRT
<213> Homo sapien

<400> 5928
 Met Ala Leu Ala Gly Ala Pro Ala Gly Gly Pro Cys Ala Pro Ala
   1               5                  10                  15

 Leu Glu Ala Leu Leu Gly Ala Gly Ala Leu Arg Leu Leu Asp Ser
                  20                  25                  30

 Ser Gln Ile Val Ile Ile Ser Ala Ala Gln Asp Ala Ser Ala Pro
                  35                  40                  45

 Pro Ala Pro Thr Gly Pro Ala Ala Pro Ala Ala Gly Pro Cys Asp
                  50                  55                  60

 Pro Asp Leu Leu Leu Phe Ala Thr Pro Gln Ala Pro Arg Pro Thr
                  65                  70                  75

 Pro Ser Ala Pro Arg Pro Ala Leu Gly Arg Pro Pro Val Lys Arg
                  80                  85                  90

 Arg Leu Asp Leu Glu Thr Asp His Gln Tyr Leu Ala Glu Ser Ser
                  95                 100                 105

 Gly Pro Ala Arg Gly Arg Gly Arg His Pro Gly Lys Gly Val Lys
                 110                 115                 120

 Ser Pro Gly Glu Lys Ser Arg Tyr Glu Thr Ser Leu Asn Leu Thr
                 125                 130                 135

 Thr Lys Arg Phe Leu Glu Leu Leu Ser His Ser Ala Asp Gly Val
                 140                 145                 150

 Val Asp Leu Asn Trp Ala Ala Glu Val Leu Lys Val Gln Lys Arg
                 155                 160                 165

 Arg Ile Tyr Asp Ile Thr Asn Val Leu Glu Gly Ile Gln Leu Ile
                 170                 175                 180

 Ala Lys Lys Ser Lys Asn His Ile Gln Trp Leu Gly Ser His Thr
                 185                 190                 195

 Thr Val Gly Val Gly Gly Arg Leu Glu Gly Leu Thr Gln Asp Leu
                 200                 205                 210

 Arg Gln Leu Gln Glu Ser Glu Gln Gln Leu Asp His Leu Met Asn
                 215                 220                 225

 Ile Cys Thr Thr Gln Leu Arg Leu Leu Ser Glu Asp Thr Asp Ser
                 230                 235                 240

 Gln Arg Leu Ala Tyr Val Thr Cys Gln Asp Leu Arg Ser Ile Ala
                 245                 250                 255

 Asp Pro Ala Glu Gln Met Val Met Val Ile Lys Ala Pro Pro Glu
                 260                 265                 270

 Thr Gln Leu Gln Ala Val Asp Ser Ser Glu Asn Phe Gln Ile Ser
                 275                 280                 285

 Leu Lys Ser Lys Gln Gly Pro Ile Asp Val Phe Leu Cys Pro Glu
                 290                 295                 300

 Glu Thr Val Gly Gly Ile Ser Pro Gly Lys Thr Pro Ser Gln Glu
                 305                 310                 315

 Val Thr Ser Glu Glu Glu Asn Arg Ala Thr Asp Ser Ala Thr Ile
                 320                 325                 330

 Val Ser Pro Pro Pro Ser Ser Pro Pro Ser Ser Leu Thr Thr Asp
                 335                 340                 345

 Pro Ser Gln Ser Leu Leu Ser Leu Glu Gln Glu Pro Leu Leu Ser
                 350                 355                 360

 Arg Met Gly Ser Leu Arg Ala Pro Val Asp Glu Asp Arg Leu Ser
                 365                 370                 375

 Pro Leu Val Ala Ala Asp Ser Leu Leu Glu His Val Arg Glu Asp
                 380                 385                 390

 Phe Ser Gly Leu Leu Pro Glu Glu Phe Ile Ser Leu Ser Pro Pro
                 395                 400                 405

 His Glu Ala Leu Asp Tyr His Phe Gly Leu Glu Glu Gly Glu Gly
                 410                 415                 420

 Ile Arg Asp Leu Phe Asp Cys Asp Phe Gly Asp Leu Thr Pro Leu
                 425                 430                 435

 Asp Phe


<210> 5929
<211> 3587
<212> DNA
<213> Homo sapien

<400> 5929
 gaattcagca caatgaagga gccatggaat gccaatttaa cgtcagtctt 50

 gtacttgaag ggaaaaaaaa cacttgtaat ggtggcaaca gtgaagctgt 100

 tcctttaaca tccccaaata tagccaagtt tagcactcca ccagccatcc 150

 tcagaaagaa gagaaaaatg cgagtgggtc attccccagg cagcgaactt 200

 agggatggct cattgaacga tggtggtaat atggcgctaa aacatacacc 250

 actgaaaaca ctaccatttt ctccttcaca gtttttcaac acatgtcctg 300

 gtaatgaaca acttaatata gaaaatcctt catttacatc aacccctatt 350

 tgtgggcaga aagctctcat tacaactcct cttcataagg aaacaactcc 400

 caaagatcaa aaggaaaatg tagggtttag aacacctact attagaagat 450

 ctatactggg taccacacca agaactccta ctccttttaa gaatgcgctt 500

 gctgctcagg agaaaaaata tggacctctt aaaattgtgt cccagccact 550

 tgctttcttg gaagaagata ttcgggaagt tttaaaagaa gaaactggaa 600

 cagacctatt cctcaaagag gaagatgaac ctgcttacaa aagctgcaaa 650

 caagagaata ccgcttctgg gaagaaagtc agaaaatcac tagtcttaga 700

 taattgggaa aaagaagaat caggcactca actgttgact gaagacattt 750

 cagacatgca gtcagaaaat agatttacta catccttatt aatgatacca 800

 ttattggaaa tacatgacaa taggtgcaac ttgattcctg aaaaacaaga 850

 tataaattca accaacaaaa catatacact tactaaaaag aaaccaaacc 900

 ctaacacttc caaagttgtc aaattggaaa agaatcttca gtcaaattgt 950

 gaatgggaaa cagtggttta tgggaagaca gaagaccaac ttattatgac 1000

 tgaacaagca agaagatatc tgagtactta cacagctacc agtagtactt 1050

 caagagctct catactgtaa ttgttattaa aattgatgaa atgccccact 1100

 cccttactgc agtctctact aaattaggtt gcagtgaaat ttttctcaat 1150

 tagttgtttt taaagttgta agataccctt ttaatacagc atcttttttc 1200

 tattctatat agtaggcaga aagctagtaa gtcacttaag gggtagatag 1250

 tttcatagtt tattttttaa gagatgagat ttttaaaaat tgtttttaaa 1300

 gaacaagatg ggaaaataat agaatgttca tggatttcta aaagtaaatt 1350

 ctcatatatt ttcttcacaa gatatatgtt gctactctct tgatgctgca 1400

 gttttgttat agataggtgt atgagtatat atgatttctg aaattagtct 1450

 atgtatggaa agcacacatg attttatgaa ggtacttttg cccatgtgct 1500

 gatttactta ggctaccatt tacaaagaaa cacattgaaa aggaatttaa 1550

 aggaaggata gaaagttgca ctactaattt tttgtttttt ttttcagaag 1600

 cagtaaaatt aactacagtg ttaaatgtat ttatttgagc atagtactga 1650

 aaacaaaaag cattcaaaaa agagtttttt ctttattagt aaatagtatt 1700

 ttcttaatct cagaggagct gagagttttg ttgaatgtat tgtacagtat 1750

 gtaggagcag gagaactttg taaattggaa agaagtctgt ttttataatt 1800

 tatttttatt tttaaagctt aaatgtagat atttatagta tacagggagc 1850

 ctagaagcca atgttgtttc ctgttattac agctaacaca gtaaagaata 1900

 attttgactt taagtatgaa acagtagtaa gttatagctg caaagaatac 1950

 aatatctata ctgtatgtca catctaccta aatgttgcac tatgcccttt 2000

 aaatcatgct ggttataaag tagttctaaa aatgtactaa ataataattt 2050

 aatattttct ttttaaatta tatcgggggt ggtcatatac attaatctgg 2100

 tgatttgtat atgtgtttga aattttttgc ttttgtttaa aaaaaaataa 2150

 tatggtacct tggtccctaa aaacagtctg cacttagaag ttatatttac 2200

 tcagtgtttc agaagtggag aacttatctt ttatttataa aaatattttg 2250

 tcctttttta aatgttttgt gtttctctac aggttacaac agttgcttca 2300

 gttgcctgtt ttaggtgttt gcacttattt tatttcttct tgaaagaatt 2350

 tttatttgct tttgtggtag agattatatg taattttttt tcagtcatat 2400

 aatggtgtgc tgtcaactta aacactgaca ggtaaataga attgtacact 2450

 gtagtttgaa ttatttataa ttgacacact ctctccctct ccactcctga 2500

 agtatgctgc tatagaaaat agcagaatcg gcttgctgct acgagagaag 2550

 gaaagagcga ccaccacttg cactgtgtga aaagataaaa aacaaatgat 2600

 ggcaagttct caagttaact aaatggaatc aaccattacc aggcaaattc 2650

 ttgcaaatac caaaatacta ctatgcctta taaaacaaaa tgaaagcagg 2700

 ttaagatttt ctgctctgtt tgtatgttaa tagaaatgga aatactaagt 2750

 attttaatgc ttagctattg aacagtagac ctaaaagggt tttaagctat 2800

 ttaaatctac ttgctagttt ttgcatattt tatatatata tatatttata 2850

 tatatatata gtgagaagtg aagaaaatgt atggtactaa gattatgcct 2900

 tattgataaa tagataaacc aatttgaatc ctcttagcat gtttaagtat 2950

 gttgattgct ttctaattaa tgaacttctc acagaaattt cacttagtga 3000

 aaccaatgat tgtagcaaac tcatactgga tcatttcagt taccttgaac 3050

 taatagcaca taatggtttt ttgttgttgt tgtttttaat gtagccctta 3100

 cctggatata catagtctgc aatcaccaaa gtataatatc ttgtaaggct 3150

 atatttttta aagcatattt tttcttgagc attaaattat cctaaatggt 3200

 aatatattgt ggataagtct gggcttattg gacataatac atatttgggt 3250

 tggtactggt tgaatccttc agttaactgc tttgttgctt tttgcaagat 3300

 tttttatctt aaacatgtca ggcatcttaa gtcaccttta tactgttttg 3350

 ttcctctgag tttctttcag tatgttatac aaatgccaga cataacatgt 3400

 agcagccata cttgcatgga aactgactac acatacataa tactgcattt 3450

 tattgtaagg ttttcacatt aatacagcaa ttaccctgac taaattgagt 3500

 tttgtgatat atggaaaact tcattgtaag agaatcttgc atacaatgtt 3550

 gactattaac atccaaaata aagcatctgt gtacaag 3587

<210> 5930
<211> 355
<212> PRT
<213> Homo sapien

<400> 5930
 Ile Gln His Asn Glu Gly Ala Met Glu Cys Gln Phe Asn Val Ser
   1               5                  10                  15

 Leu Val Leu Glu Gly Lys Lys Asn Thr Cys Asn Gly Gly Asn Ser
                  20                  25                  30

 Glu Ala Val Pro Leu Thr Ser Pro Asn Ile Ala Lys Phe Ser Thr
                  35                  40                  45

 Pro Pro Ala Ile Leu Arg Lys Lys Arg Lys Met Arg Val Gly His
                  50                  55                  60

 Ser Pro Gly Ser Glu Leu Arg Asp Gly Ser Leu Asn Asp Gly Gly
                  65                  70                  75

 Asn Met Ala Leu Lys His Thr Pro Leu Lys Thr Leu Pro Phe Ser
                  80                  85                  90

 Pro Ser Gln Phe Phe Asn Thr Cys Pro Gly Asn Glu Gln Leu Asn
                  95                 100                 105

 Ile Glu Asn Pro Ser Phe Thr Ser Thr Pro Ile Cys Gly Gln Lys
                 110                 115                 120

 Ala Leu Ile Thr Thr Pro Leu His Lys Glu Thr Thr Pro Lys Asp
                 125                 130                 135

 Gln Lys Glu Asn Val Gly Phe Arg Thr Pro Thr Ile Arg Arg Ser
                 140                 145                 150

 Ile Leu Gly Thr Thr Pro Arg Thr Pro Thr Pro Phe Lys Asn Ala
                 155                 160                 165

 Leu Ala Ala Gln Glu Lys Lys Tyr Gly Pro Leu Lys Ile Val Ser
                 170                 175                 180

 Gln Pro Leu Ala Phe Leu Glu Glu Asp Ile Arg Glu Val Leu Lys
                 185                 190                 195

 Glu Glu Thr Gly Thr Asp Leu Phe Leu Lys Glu Glu Asp Glu Pro
                 200                 205                 210

 Ala Tyr Lys Ser Cys Lys Gln Glu Asn Thr Ala Ser Gly Lys Lys
                 215                 220                 225

 Val Arg Lys Ser Leu Val Leu Asp Asn Trp Glu Lys Glu Glu Ser
                 230                 235                 240

 Gly Thr Gln Leu Leu Thr Glu Asp Ile Ser Asp Met Gln Ser Glu
                 245                 250                 255

 Asn Arg Phe Thr Thr Ser Leu Leu Met Ile Pro Leu Leu Glu Ile
                 260                 265                 270

 His Asp Asn Arg Cys Asn Leu Ile Pro Glu Lys Gln Asp Ile Asn
                 275                 280                 285

 Ser Thr Asn Lys Thr Tyr Thr Leu Thr Lys Lys Lys Pro Asn Pro
                 290                 295                 300

 Asn Thr Ser Lys Val Val Lys Leu Glu Lys Asn Leu Gln Ser Asn
                 305                 310                 315

 Cys Glu Trp Glu Thr Val Val Tyr Gly Lys Thr Glu Asp Gln Leu
                 320                 325                 330

 Ile Met Thr Glu Gln Ala Arg Arg Tyr Leu Ser Thr Tyr Thr Ala
                 335                 340                 345

 Thr Ser Ser Thr Ser Arg Ala Leu Ile Leu
                 350                 355

<210> 5931
<211> 1143
<212> DNA
<213> Homo sapien

<400> 5931
 ggagctctgg aggcggggct tcgagcgtgg ctcgtgggtt ttccgtgaag 50

 tcgcggtgca gcggtgggcg gcatgtctgt ggccggtggg gagattcgtg 100

 gggacacggg gggagaggac actgctgctc ccggccggtt cagcttcagc 150

 ccggagccca cgctcgagga catccgccgc ctccatgctg agtttgctgc 200

 ggaacgagac tgggaacagt tccatcagcc tcggaatctc ctcctggcct 250

 tggttgggga agtgggggag ctggcagaac tctttcagtg gaaaaccgat 300

 ggggaacctg gcccccaagg ctggtccccc agggaacggg cagcccttca 350

 agaggagctt agtgacgtcc tcatctacct ggtggcatta gcagcccgct 400

 gccgtgtgga tctgccgcta gcagtgctct ccaaaatgga catcaaccgg 450

 cgacgctacc cagcccatct ggcccgcagc tcttcccgca agtatacaga 500

 attgccccat ggggccatct ctgaagacca ggctgtgggg cctgcggaca 550

 ttccctgtga ctccacaggc cagacctcaa cctagaaaga tggccacagg 600

 acttgcaact cagggtggtg tctgaagagc agagagtggc ctggccctgg 650

 agcctttttc tagtcttttc agaatagatc atgggcctga ggcctccact 700

 tcttgaggtc tgaggcccag cagcctctag aaggtagcct cctggtgttt 750

 gttctcccag taaaatggtt ttgggcgata acttctagat tattcctgga 800

 tggccaggga ggctctctgt ctcagcaggt gatgacgggg gtaccagggg 850

 tgcctctgag acccattctc gtgtttccct gttgtacctt ttgcctgcag 900

 ggcagagaga tctggtttct agcaaattcc cagtaggatg tcatgtaagt 950

 tccttccccc tcttagagat tgaaggctgt aagagtccag atggtggagc 1000

 caggctgtct gggttcaaat gccatctttg acacttgcaa gctaaatgac 1050

 attactcaaa ttaatcgttc tgcacttcag cttccttgtc tatcaaataa 1100

 aaagaatagt acctgcccaa aaaaaaaaaa aaaaaaaaaa aaa 1143

<210> 5932
<211> 170
<212> PRT
<213> Homo sapien

<400> 5932
 Met Ser Val Ala Gly Gly Glu Ile Arg Gly Asp Thr Gly Gly Glu
   1               5                  10                  15

 Asp Thr Ala Ala Pro Gly Arg Phe Ser Phe Ser Pro Glu Pro Thr
                  20                  25                  30

 Leu Glu Asp Ile Arg Arg Leu His Ala Glu Phe Ala Ala Glu Arg
                  35                  40                  45

 Asp Trp Glu Gln Phe His Gln Pro Arg Asn Leu Leu Leu Ala Leu
                  50                  55                  60

 Val Gly Glu Val Gly Glu Leu Ala Glu Leu Phe Gln Trp Lys Thr
                  65                  70                  75

 Asp Gly Glu Pro Gly Pro Gln Gly Trp Ser Pro Arg Glu Arg Ala
                  80                  85                  90

 Ala Leu Gln Glu Glu Leu Ser Asp Val Leu Ile Tyr Leu Val Ala
                  95                 100                 105

 Leu Ala Ala Arg Cys Arg Val Asp Leu Pro Leu Ala Val Leu Ser
                 110                 115                 120

 Lys Met Asp Ile Asn Arg Arg Arg Tyr Pro Ala His Leu Ala Arg
                 125                 130                 135

 Ser Ser Ser Arg Lys Tyr Thr Glu Leu Pro His Gly Ala Ile Ser
                 140                 145                 150

 Glu Asp Gln Ala Val Gly Pro Ala Asp Ile Pro Cys Asp Ser Thr
                 155                 160                 165

 Gly Gln Thr Ser Thr
                 170

<210> 5933
<211> 3372
<212> DNA
<213> Homo sapien

<400> 5933
 tacaaccagg ctcaactgtt gcatggtagc agatttgcaa acatgagtgc 50

 tgaggggtac cagtacagag cgctgtatga ttataaaaag gaaagagaag 100

 aagatattga cttgcacttg ggtgacatat tgactgtgaa taaagggtcc 150

 ttagtagctc ttggattcag tgatggacag gaagccaggc ctgaagaaat 200

 tggctggtta aatggctata atgaaaccac aggggaaagg ggggactttc 250

 cgggaactta cgtagaatat attggaagga aaaaaatctc gcctcccaca 300

 ccaaagcccc ggccacctcg gcctcttcct gttgcaccag gttcttcgaa 350

 aactgaagca gatgttgaac aacaagcttt gactctcccg gatcttgcag 400

 agcagtttgc ccctcctgac attgccccgc ctcttcttat caagctcgtg 450

 gaagccattg aaaagaaagg tctggaatgt tcaactctat acagaacaca 500

 gagctccagc aacctggcag aattacgaca gcttcttgat tgtgatacac 550

 cctccgtgga cttggaaatg atcgatgtgc acgttttggc tgacgctttc 600

 aaacgctatc tcctggactt accaaatcct gtcattccag cagccgttta 650

 cagtgaaatg atttctttag ctccagaagt acaaagctcc gaagaatata 700

 ttcagctatt gaagaagctt attaggtcgc ctagcatacc tcatcagtat 750

 tggcttacgc ttcagtattt gttaaaacat ttcttcaagc tctctcaaac 800

 ctccagcaaa aatctgttga atgcaagagt actctctgaa attttcagcc 850

 ctatgctttt cagattctca gcagccagct ctgataatac tgaaaacctc 900

 ataaaagtta tagaaatttt aatctcaact gaatggaatg aacgacagcc 950

 tgcaccagca ctgcctccta aaccaccaaa acctactact gtagccaaca 1000

 acggtatgaa taacaatatg tccttacaaa atgctgaatg gtactgggga 1050

 gatatctcga gggaagaagt gaatgaaaaa cttcgagata cagcagacgg 1100

 gacctttttg gtacgagatg cgtctactaa aatgcatggt gattatactc 1150

 ttacactaag gaaaggggga aataacaaat taatcaaaat atttcatcga 1200

 gatgggaaat atggcttctc tgacccatta accttcagtt ctgtggttga 1250

 attaataaac cactaccgga atgaatctct agctcagtat aatcccaaat 1300

 tggatgtgaa attactttat ccagtatcca aataccaaca ggatcaagtt 1350

 gtcaaagaag ataatattga agctgtaggg aaaaaattac atgaatataa 1400

 cactcagttt caagaaaaaa gtcgagaata tgatagatta tatgaagaat 1450

 atacccgcac atcccaggaa atccaaatga aaaggacagc tattgaagca 1500

 tttaatgaaa ccataaaaat atttgaagaa cagtgccaga cccaagagcg 1550

 gtacagcaaa gaatacatag aaaagtttaa acgtgaaggc aatgagaaag 1600

 aaatacaaag gattatgcat aattatgata agttgaagtc tcgaatcagt 1650

 gaaattattg acagtagaag aagattggaa gaagacttga agaagcaggc 1700

 agctgagtat cgagaaattg acaaacgtat gaacagcatt aaaccagacc 1750

 ttatccagct gagaaagacg agagaccaat acttgatgtg gttgactcaa 1800

 aaaggtgttc ggcaaaagaa gttgaacgag tggttgggca atgaaaacac 1850

 tgaagaccaa tattcactgg tggaagatga tgaagatttg ccccatcatg 1900

 atgagaagac atggaatgtt ggaagcagca accgaaacaa agctgaaaac 1950

 ctgttgcgag ggaagcgaga tggcactttt cttgtccggg agagcagtaa 2000

 acagggctgc tatgcctgct ctgtagtggt ggacggcgaa gtaaagcatt 2050

 gtgtcataaa caaaacagca actggctatg gctttgccga gccctataac 2100

 ttgtacagct ctctgaaaga actggtgcta cattaccaac acacctccct 2150

 tgtgcagcac aacgactccc tcaatgtcac actagcctac ccagtatatg 2200

 cacagcagag gcgatgaagc gcttactctt tgatccttct cctgaagttc 2250

 agccaccctg aggcctctgg aaagcaaagg gctcctctcc agtctgatct 2300

 gtgaattgag ctgcagaaac gaagccatct ttctttggat gggactagag 2350

 ctttctttca caaaaaagaa gtaggggaag acatgcagcc taaggctgta 2400

 tgatgaccac acgttcctaa gctggagtgc ttatcccttc tttttctttt 2450

 tttctttggt ttaatttaaa gccacaacca catacaacac aaagagaaaa 2500

 agaaatgcaa aaatctctgc gtgcagggac aaagaggcct ttaaccatgg 2550

 tgcttgttaa tgctttctga agctttacca gctgaaagtt gggactctgg 2600

 agagcggagg agagagaggc agaagaaccc tggcctgaga aggtttggtc 2650

 cagcctggtt tagcctggat gttgctgtgc acggtggacc cagacacatc 2700

 gcactgtgga ttatttcatt ttgtaacaaa tgaacgatat gtagcagaaa 2750

 ggcacgtcca ctcacaaggg acgctttggg agaatgtcag ttcatgtatg 2800

 ttcagaagaa attctgtcat agaaagtgcc agaaagtgtt taacttgtca 2850

 aaaaacaaaa acccagcaac agaaaaatgg agtttggaaa acaggactta 2900

 aaatgacatt cagtatataa aatatgtaca taatattgga tgactaacta 2950

 tcaaatagat ggatttgtat caataccaaa tagcttctgt tttgttttgc 3000

 tgaaggctaa attcacagcg ctatgcaatt cttaattttc attaagttgt 3050

 tatttcagtt ttaaatgtac cttcagaata agcttcccca ccccagtttt 3100

 tgttgcttga aaatattgtt gtcccggatt tttgttaata ttcatttttg 3150

 ttatcctttt ttaaaaataa atgtacagga tgccagtaaa aaaaaaaatg 3200

 gcttcagaat taaaactatg aaatatttta cagtttttct tgtacagagt 3250

 acttgctgtt agcccaaggt taaaaagttc ataacagatt ttttttggac 3300

 tgttttgttg ggcagtgcct gataagcttc aaagctgctt tattcaataa 3350

 aaaaaaaacc cgaattcact gg 3372

<210> 5934
<211> 724
<212> PRT
<213> Homo sapien

<400> 5934
 Met Ser Ala Glu Gly Tyr Gln Tyr Arg Ala Leu Tyr Asp Tyr Lys
   1               5                  10                  15

 Lys Glu Arg Glu Glu Asp Ile Asp Leu His Leu Gly Asp Ile Leu
                  20                  25                  30

 Thr Val Asn Lys Gly Ser Leu Val Ala Leu Gly Phe Ser Asp Gly
                  35                  40                  45

 Gln Glu Ala Arg Pro Glu Glu Ile Gly Trp Leu Asn Gly Tyr Asn
                  50                  55                  60

 Glu Thr Thr Gly Glu Arg Gly Asp Phe Pro Gly Thr Tyr Val Glu
                  65                  70                  75

 Tyr Ile Gly Arg Lys Lys Ile Ser Pro Pro Thr Pro Lys Pro Arg
                  80                  85                  90

 Pro Pro Arg Pro Leu Pro Val Ala Pro Gly Ser Ser Lys Thr Glu
                  95                 100                 105

 Ala Asp Val Glu Gln Gln Ala Leu Thr Leu Pro Asp Leu Ala Glu
                 110                 115                 120

 Gln Phe Ala Pro Pro Asp Ile Ala Pro Pro Leu Leu Ile Lys Leu
                 125                 130                 135

 Val Glu Ala Ile Glu Lys Lys Gly Leu Glu Cys Ser Thr Leu Tyr
                 140                 145                 150

 Arg Thr Gln Ser Ser Ser Asn Leu Ala Glu Leu Arg Gln Leu Leu
                 155                 160                 165

 Asp Cys Asp Thr Pro Ser Val Asp Leu Glu Met Ile Asp Val His
                 170                 175                 180

 Val Leu Ala Asp Ala Phe Lys Arg Tyr Leu Leu Asp Leu Pro Asn
                 185                 190                 195

 Pro Val Ile Pro Ala Ala Val Tyr Ser Glu Met Ile Ser Leu Ala
                 200                 205                 210

 Pro Glu Val Gln Ser Ser Glu Glu Tyr Ile Gln Leu Leu Lys Lys
                 215                 220                 225

 Leu Ile Arg Ser Pro Ser Ile Pro His Gln Tyr Trp Leu Thr Leu
                 230                 235                 240

 Gln Tyr Leu Leu Lys His Phe Phe Lys Leu Ser Gln Thr Ser Ser
                 245                 250                 255

 Lys Asn Leu Leu Asn Ala Arg Val Leu Ser Glu Ile Phe Ser Pro
                 260                 265                 270

 Met Leu Phe Arg Phe Ser Ala Ala Ser Ser Asp Asn Thr Glu Asn
                 275                 280                 285

 Leu Ile Lys Val Ile Glu Ile Leu Ile Ser Thr Glu Trp Asn Glu
                 290                 295                 300

 Arg Gln Pro Ala Pro Ala Leu Pro Pro Lys Pro Pro Lys Pro Thr
                 305                 310                 315

 Thr Val Ala Asn Asn Gly Met Asn Asn Asn Met Ser Leu Gln Asn
                 320                 325                 330

 Ala Glu Trp Tyr Trp Gly Asp Ile Ser Arg Glu Glu Val Asn Glu
                 335                 340                 345

 Lys Leu Arg Asp Thr Ala Asp Gly Thr Phe Leu Val Arg Asp Ala
                 350                 355                 360

 Ser Thr Lys Met His Gly Asp Tyr Thr Leu Thr Leu Arg Lys Gly
                 365                 370                 375

 Gly Asn Asn Lys Leu Ile Lys Ile Phe His Arg Asp Gly Lys Tyr
                 380                 385                 390

 Gly Phe Ser Asp Pro Leu Thr Phe Ser Ser Val Val Glu Leu Ile
                 395                 400                 405

 Asn His Tyr Arg Asn Glu Ser Leu Ala Gln Tyr Asn Pro Lys Leu
                 410                 415                 420

 Asp Val Lys Leu Leu Tyr Pro Val Ser Lys Tyr Gln Gln Asp Gln
                 425                 430                 435

 Val Val Lys Glu Asp Asn Ile Glu Ala Val Gly Lys Lys Leu His
                 440                 445                 450

 Glu Tyr Asn Thr Gln Phe Gln Glu Lys Ser Arg Glu Tyr Asp Arg
                 455                 460                 465

 Leu Tyr Glu Glu Tyr Thr Arg Thr Ser Gln Glu Ile Gln Met Lys
                 470                 475                 480

 Arg Thr Ala Ile Glu Ala Phe Asn Glu Thr Ile Lys Ile Phe Glu
                 485                 490                 495

 Glu Gln Cys Gln Thr Gln Glu Arg Tyr Ser Lys Glu Tyr Ile Glu
                 500                 505                 510

 Lys Phe Lys Arg Glu Gly Asn Glu Lys Glu Ile Gln Arg Ile Met
                 515                 520                 525

 His Asn Tyr Asp Lys Leu Lys Ser Arg Ile Ser Glu Ile Ile Asp
                 530                 535                 540

 Ser Arg Arg Arg Leu Glu Glu Asp Leu Lys Lys Gln Ala Ala Glu
                 545                 550                 555

 Tyr Arg Glu Ile Asp Lys Arg Met Asn Ser Ile Lys Pro Asp Leu
                 560                 565                 570

 Ile Gln Leu Arg Lys Thr Arg Asp Gln Tyr Leu Met Trp Leu Thr
                 575                 580                 585

 Gln Lys Gly Val Arg Gln Lys Lys Leu Asn Glu Trp Leu Gly Asn
                 590                 595                 600

 Glu Asn Thr Glu Asp Gln Tyr Ser Leu Val Glu Asp Asp Glu Asp
                 605                 610                 615

 Leu Pro His His Asp Glu Lys Thr Trp Asn Val Gly Ser Ser Asn
                 620                 625                 630

 Arg Asn Lys Ala Glu Asn Leu Leu Arg Gly Lys Arg Asp Gly Thr
                 635                 640                 645

 Phe Leu Val Arg Glu Ser Ser Lys Gln Gly Cys Tyr Ala Cys Ser
                 650                 655                 660

 Val Val Val Asp Gly Glu Val Lys His Cys Val Ile Asn Lys Thr
                 665                 670                 675

 Ala Thr Gly Tyr Gly Phe Ala Glu Pro Tyr Asn Leu Tyr Ser Ser
                 680                 685                 690

 Leu Lys Glu Leu Val Leu His Tyr Gln His Thr Ser Leu Val Gln
                 695                 700                 705

 His Asn Asp Ser Leu Asn Val Thr Leu Ala Tyr Pro Val Tyr Ala
                 710                 715                 720

 Gln Gln Arg Arg


<210> 5935
<211> 1716
<212> DNA
<213> Homo sapien

<400> 5935
 aagtgcgcat ggggacgcta tagcaattcg tttgctgtcc ttcctctcct 50

 tcgaagatga caaggcctac catcgtttct tcctgccttt gggccgtcag 100

 gcagttggtt gggacccgct ccaaccctcg gttcttcctg caatacagtg 150

 gatacaattt gtcatggcta ctctgagtgt tataggttca agttcactta 200

 ttgcctatgc tgtattccat aatatacaga aatctccaga gataagacca 250

 cttttttatc tgagcttctg tgacctgctc ctgggacttt gctggctcac 300

 ggagacactt ctctatggag cttcagtagc gaataaggac atcatctgct 350

 ataacctaca agcagttgga cagttctgga ggctggaagg tccaagatta 400

 agataatcag cagatctggt gtctggggag acggggtttc gccatgtttg 450

 ccaggctggt cctgaatgcc tgacctcaag tgattcaccg cttgggcctc 500

 ccaaagtgct gggattacag gtgtgagcca ctgcacctgg cctccttaaa 550

 tgtatcttta tggcctaatt ttcacctttg cacccagttg atattctaca 600

 tttcctcatt tctctacacc gtcaattaca tctggtattt gtacacagag 650

 ctgaggatga aacacaccca gagtggacag agcacatctc cactggtgat 700

 agattatact tgtcgagttt gtcaaatggc ctttgttttc tcaagcctga 750

 tacctctgct attgatgaca cctgtattct gtctgggaaa tactagtgaa 800

 tgtttccaaa acttcagtca gagccacaag tgtatcttga tgcactcacc 850

 accatcagcc atggctgaac ttccaccttc tgccaacaca tctgtctgta 900

 gcacacttta tttttatggt atcgccattt tcctgggcag ctttgtactc 950

 agcctcctta ccattatggt cttacttatc cgagcccaga cattgtataa 1000

 gaagtttgtg aagtcaactg gctttctggg gagtgaacag tgggcagtga 1050

 ttcacattgt ggaccaacgg gtgcgcttct acccagtggc cttcttttgc 1100

 tgctggggcc cagctgtcat tctaatgatc ataaagctga ctaagccaca 1150

 ggacaccaag cttcacatgg ccctttatgt tctccaggct ctaacggcaa 1200

 catctcaggg tctactcaac tgtggagtat atggctggac gcagcacaaa 1250

 ttccaccaac taaagcagga ggctcggcgt gatgcagata cccagacacc 1300

 attattatgc tcacagaaga gattctatag caggggctta aattcactgg 1350

 aatccaccct gacttttcct gccagtactt ctaccatttt ttgaagctac 1400

 aatactggaa catccaggaa ctggagttat tctacgctaa tggattggaa 1450

 agaatgttgg gaaaggacat cttaaatctt ttctaactat gccctaaact 1500

 gcagaactca aaggaaatat agtgccattg ttagtagtca ttctagatga 1550

 attgggagta tctctccagt tattcccaga ttcactagtg atccttaaag 1600

 tctctattca gggagaggaa gacactttcc atctcagaga tagactcgtg 1650

 ttaccttgat ggatattgga tttgtctaag tctcttctag aaaaaataaa 1700

 ttctagatta ttattt 1716

<210> 5936
<211> 245
<212> PRT
<213> Homo sapien

<400> 5936
 Met Lys His Thr Gln Ser Gly Gln Ser Thr Ser Pro Leu Val Ile
   1               5                  10                  15

 Asp Tyr Thr Cys Arg Val Cys Gln Met Ala Phe Val Phe Ser Ser
                  20                  25                  30

 Leu Ile Pro Leu Leu Leu Met Thr Pro Val Phe Cys Leu Gly Asn
                  35                  40                  45

 Thr Ser Glu Cys Phe Gln Asn Phe Ser Gln Ser His Lys Cys Ile
                  50                  55                  60

 Leu Met His Ser Pro Pro Ser Ala Met Ala Glu Leu Pro Pro Ser
                  65                  70                  75

 Ala Asn Thr Ser Val Cys Ser Thr Leu Tyr Phe Tyr Gly Ile Ala
                  80                  85                  90

 Ile Phe Leu Gly Ser Phe Val Leu Ser Leu Leu Thr Ile Met Val
                  95                 100                 105

 Leu Leu Ile Arg Ala Gln Thr Leu Tyr Lys Lys Phe Val Lys Ser
                 110                 115                 120

 Thr Gly Phe Leu Gly Ser Glu Gln Trp Ala Val Ile His Ile Val
                 125                 130                 135

 Asp Gln Arg Val Arg Phe Tyr Pro Val Ala Phe Phe Cys Cys Trp
                 140                 145                 150

 Gly Pro Ala Val Ile Leu Met Ile Ile Lys Leu Thr Lys Pro Gln
                 155                 160                 165

 Asp Thr Lys Leu His Met Ala Leu Tyr Val Leu Gln Ala Leu Thr
                 170                 175                 180

 Ala Thr Ser Gln Gly Leu Leu Asn Cys Gly Val Tyr Gly Trp Thr
                 185                 190                 195

 Gln His Lys Phe His Gln Leu Lys Gln Glu Ala Arg Arg Asp Ala
                 200                 205                 210

 Asp Thr Gln Thr Pro Leu Leu Cys Ser Gln Lys Arg Phe Tyr Ser
                 215                 220                 225

 Arg Gly Leu Asn Ser Leu Glu Ser Thr Leu Thr Phe Pro Ala Ser
                 230                 235                 240

 Thr Ser Thr Ile Phe
                 245

<210> 5937
<211> 956
<212> DNA
<213> Homo sapien

<400> 5937
 agaaagtcga cgggcgtggc gggggagggg acgctgaggg cccatgtgct 50

 gaaaatccga agtgccgcgg aaagtggagg tgagggccgc ccgccctaga 100

 ggtgcccgtc cgagaggcag agctgacaag gaaggtttcg agcgttttgc 150

 tggcaaaggg atttcttaca acctccaggc atgcgtcttt ctgccctgct 200

 ggccttggca tccaaggtca ctctgccccc ccattaccgc tatgggatga 250

 gccccccagg ctctgttgca gacaagagga agaacccccc atggatcagg 300

 cggcgcccag tggttgtgga acccatctct gatgaagact ggtatctgtt 350

 ctgtggggac acggtggaga tcctagaagg caaggatgcc gggaagcagg 400

 gcaaagtggt tcaagttatc cggcagcgaa actgggtggt cgtgggaggg 450

 ctgaacacac attaccgcta cattggcaag accatggatt accggggaac 500

 catgatccct agtgaagccc ccttgctcca ccgccaggtc aaacttgtgg 550

 atcctatgga caggaaaccc actgagatcg agtggagatt tactgaagca 600

 ggagagcggg tacgagtctc cacacgatca gggagaatta tccctaaacc 650

 cgaatttccc agagctgatg gcatcgtccc tgaaacgtgg attgatggcc 700

 ccaaagacac atcagtggaa gatgctttag aaagaaccta tgtgccctgt 750

 ctaaagacac tgcaggagga ggtgatggag gccatgggga tcaaggagac 800

 ccggaaatac aagaaggtct attggtattg agcctggggc agagcagctc 850

 ctccccaact tctgtcccag ccttgaaggc tgaggcactt ctttttcaga 900

 tgccaataaa gagcacttta tgagtccaaa aaaaaaaaaa aaaaaaaaaa 950

 aaaaaa 956

<210> 5938
<211> 216
<212> PRT
<213> Homo sapien

<400> 5938
 Met Arg Leu Ser Ala Leu Leu Ala Leu Ala Ser Lys Val Thr Leu
   1               5                  10                  15

 Pro Pro His Tyr Arg Tyr Gly Met Ser Pro Pro Gly Ser Val Ala
                  20                  25                  30

 Asp Lys Arg Lys Asn Pro Pro Trp Ile Arg Arg Arg Pro Val Val
                  35                  40                  45

 Val Glu Pro Ile Ser Asp Glu Asp Trp Tyr Leu Phe Cys Gly Asp
                  50                  55                  60

 Thr Val Glu Ile Leu Glu Gly Lys Asp Ala Gly Lys Gln Gly Lys
                  65                  70                  75

 Val Val Gln Val Ile Arg Gln Arg Asn Trp Val Val Val Gly Gly
                  80                  85                  90

 Leu Asn Thr His Tyr Arg Tyr Ile Gly Lys Thr Met Asp Tyr Arg
                  95                 100                 105

 Gly Thr Met Ile Pro Ser Glu Ala Pro Leu Leu His Arg Gln Val
                 110                 115                 120

 Lys Leu Val Asp Pro Met Asp Arg Lys Pro Thr Glu Ile Glu Trp
                 125                 130                 135

 Arg Phe Thr Glu Ala Gly Glu Arg Val Arg Val Ser Thr Arg Ser
                 140                 145                 150

 Gly Arg Ile Ile Pro Lys Pro Glu Phe Pro Arg Ala Asp Gly Ile
                 155                 160                 165

 Val Pro Glu Thr Trp Ile Asp Gly Pro Lys Asp Thr Ser Val Glu
                 170                 175                 180

 Asp Ala Leu Glu Arg Thr Tyr Val Pro Cys Leu Lys Thr Leu Gln
                 185                 190                 195

 Glu Glu Val Met Glu Ala Met Gly Ile Lys Glu Thr Arg Lys Tyr
                 200                 205                 210

 Lys Lys Val Tyr Trp Tyr
                 215

<210> 5939
<211> 2078
<212> DNA
<213> Homo sapien

<400> 5939
 tgggcaatta accaagccat agccaatgaa tatgaagtcc ggagaaagct 50

 gctaataaaa cgtttggatg tcactgtaca atcctttggc tggtctgaca 100

 gagctaagag ccagacagaa aaattagcca aggtttacca gccgaaacgt 150

 tcagtcttat cccctaaaac tactatttct gttgcccatc ttttggctgc 200

 aaggcaggac ttgtcaaaga ttttaaggac aagcagcggc tctataagag 250

 aaaagactgc ctgtgccatc aataaggtgt tgatgggcag ggtgcctgac 300

 agaggtggta gacccaatga aatcgaacct ccacccccag agatgccacc 350

 gtggcagaag aggcaagatg gcccccagca gcaaacagga ggccgagtag 400

 gagggagagg tggctatgaa cattcctcat acggaggacg aggaggtcat 450

 gaacaaggag gcgggagagg tggacgtggt ggctatgacc atggtggccg 500

 agggggagga agaggaaata agcatcaagg aggctggaca gatggaggga 550

 gtggtggagg aggtggctac caagatggtg gttatcgaga ttcaggtttc 600

 cagccaggtg gctatcatgg tggccacagc agtggtggct atcaaggcgg 650

 aggttatggt ggcttccaaa catcttcttc atatacagga agtggatacc 700

 agggtggtgg ctaccagcag gacaatagat accaagatgg cgggcaccat 750

 ggtgatcgtg gtggtggtcg tggtgggcga ggtggtcgtg gaggccgagg 800

 tggtcgtgca ggccagggag gaggctgggg aggaagaggg agccagaatt 850

 atcaccaagg gggtcaattt gaacagcatt tccagcatgg aggttatcag 900

 tataatcatt ctggatttgg acagggaaga cattacacta gttgaggcta 950

 ccgaacttta cattttgcta gagctcaagt aatagaaact tagtttcaga 1000

 atcctgaatt cagcacctat tttgaattaa tgtgagacca caggtggcag 1050

 gcagattcct gcttggcata agcatttgta ggtcttcatt caattctgtt 1100

 agattttttt attggactta cataatgccg tttatttgag aaacacataa 1150

 catctctcct tcctatgaaa aattttttaa aaggtggtta aaattgcctt 1200

 taattgccca gtagactaat tccacagtca gaacatgcaa acttttttga 1250

 agaaattact tgaataagta gttttcatgt tttcaatatg cagttttgaa 1300

 aatgaggatt cacctagact tttttagatt tactactagg aaaccttcct 1350

 catatgaata accatttata tgtgttttgc ttaaagtatt ccaatgccta 1400

 ttttccaagc acagttctgc cccccggttg acttttatgc cacgtgtgct 1450

 tcatgatgga acttttaggt cagttcctat taaatgagct cttctgcaga 1500

 tagcacattc agtagcctta ttttgttgat ggaatactgt atcatatgct 1550

 caactctgaa aaccttgaac acggccaaaa tccataaaga ttataaaagc 1600

 aaactaagtt gtgaagctat agtacatgta ggcatttagt taagtatagc 1650

 aattcaaact gacctgcatc catccaaaac aaattcctcc ttcaacctta 1700

 tttttacttg aaatttgcta gaagaaatag caaaccgaaa tttgttttat 1750

 gcatgagtta ataccactgg ctcagcaaat acaagttagt ttgctttaag 1800

 caggtaactt tttttgtaat ggaagaaatg cactacaaag ttaagacaga 1850

 tttttgctaa gtgcaggagg ccctttatta ttgctgcaga aaacaaaagc 1900

 ctggctgagt tgatgtttta cattctccct tactgaaatc tacatgacat 1950

 gatgcttctt gctgggtttt tgtacatgta aacattgtca agctgtgaaa 2000

 gaaaatggct ggaggtgtgc tttgtgtgaa aggtgagcaa taaagtatct 2050

 gttaagttca aaaaaaaaaa aaaaaaaa 2078

<210> 5940
<211> 3000
<212> DNA
<213> Homo sapien

<400> 5940
 cccgagcggc gagacggtcc ccgccatgtc tgcggccatg agggagaggt 50

 tcgaccggtt cctgcacgag aagaactgca tgactgacct tctggccaag 100

 ctcgaggcca aaaccggcgt gaacaggagc ttcatcgctc ttggtgtcat 150

 cggactggtg gccttgtacc tggtgttcgg ttatggagcc tctctcctct 200

 gcaacctgat aggatttggc tacccagcct acatctcaat taaagctata 250

 gagagtccca acaaagaaga tgatacccag tggctgacct actgggtagt 300

 gtatggtgtg ttcagcattg ctgaattctt ctctgatatc ttcctgtcat 350

 ggttcccctt ctactacatg ctgaagtgtg gcttcctgtt gtggtgcatg 400

 gccccgagcc cttctaatgg ggctgaactg ctctacaagc gcatcatccg 450

 tcctttcttc ctgaagcacg agtcccagat ggacagtgtg gtcaaggacc 500

 ttaaagacaa ggccaaagag actgcagatg ccatcactaa agaagcgaag 550

 aaagctaccg tgaatttact gggtgaagaa aagaagagca cctaaaccag 600

 actggatgga aacttcctgc cctctctgta ccttcctact ggagcttgat 650

 gttatattag ggactgtggt ataattattt taataatgtt gccttggaaa 700

 catttttgag atattaaaga ttggaatgtg ttgtaagttt ctttgcttac 750

 ttttactgtc tatatatata gggagcactt taaacttaat gcagtgggca 800

 gtgtccacgt ttttggaaaa tgtattttgc ctctgggtag gaaaagatgt 850

 atgttgctat cctgcaggaa atataaactt aaaataaaat tatatacccc 900

 acaggctgtg tactttactg ggctctccct gcacgcattt tctctgtagt 950

 tacatttagg ataatcttta tggttctact tcctataatg tacaatttta 1000

 tataattctg aaatgttttt aatgtatttg tgcacatgta catatggaaa 1050

 tgttactgtc tgactacaac atgcatcatg ctcatgggga gggagcaggg 1100

 gaaggttgta tgtgtcattt ataacttctg tacagtaaga ccacctgcca 1150

 aaagctggag gaaccattgt gctggtgtgg tctactaaat aatactttag 1200

 gaaatacgtg attaatatgc aagtgaacaa agtgagaaat gaaatcgaat 1250

 ggagattggc ctggttgttt ccctagtata tggcatatga ataccaggat 1300

 agctttataa agcagttagt tagttactca ctctagtgat aaatcgggaa 1350

 atttacacac acacacacac acacacacac acagagtaac ctgtaactct 1400

 caattccctg aaaaactagt aatactgtct tatctgctat aaactttaca 1450

 tatttgtcta ttgtcaagat gctacaatgg aaaccatttc tggttttatc 1500

 ttcaaagcgg agaaacatgt tgatttagtc ttctttccca atcttctttt 1550

 ttaaaccagt ttaaggaact tctgaagatt tgtccacctc tgattacatg 1600

 tatgttcttg tttgtatcat tagcaacaac atgctaatga cgacacctag 1650

 ctctaagagc aattctggga gaatgaaagg aagtataaag taacccataa 1700

 tctgcttggc aatagttaag tcaatctatc ttcagttttt ctctggcctt 1750

 taaggtcaaa cacaagaggc ttccctagtt tacaagtcag agtcacttgt 1800

 agtccattta aatgccctca tccgtattct ttgtgttgat aagctgcaca 1850

 tgactacata gtaagtacag aacagtaaag ttaaaacgga tgtctccatt 1900

 gatctgccaa atcgttatag agagcaattt gtctggacta gaaaatctga 1950

 gttttacacc atactgttaa gagtcctttt gaattaaact agactaaaac 2000

 aagtgtataa ctaaactaac aagattaaat atccagccag tacagtattt 2050

 tttaaggcaa ataaagatga ttagctcacc ttgagataac aatcaggtaa 2100

 gatcataaca atgtctcatg atgtaaaaaa tattaaagat atcaatacta 2150

 agtgacagta tcactctaat ataatatgga tcagagcatt tattttgggg 2200

 aggaaaacag tggtgattac cggcatttta ttaaacttaa aactttgtag 2250

 aaagcaaaca aaattgttct tgggagaaaa tcaactttta gattaaaaaa 2300

 attttaagta tctaggagta tttaaatcct tttcccataa ataaaagtac 2350

 agttttcttg gtggcagaat gaaaatcagc aacttctagc atatagacta 2400

 tataatcaga ttgacagcat atagaatata ttatcagaca agatgaggag 2450

 gtataaaagt tactattgct cataatgact tacaggctaa aattagtttt 2500

 aaaatactat attaaattct gaatgcaatt tttttttgtt cccttgagac 2550

 caaaatttaa gttaactgtt gctggcagtc taagtgtaaa tgttaacagc 2600

 aggagaagtt aagaattgag cagttctgtt gcatgatttc ccaaatgaaa 2650

 tactgccttg gctagagttt gaaaaactaa ttgagcctgt gcctggctag 2700

 aaaacaagcg tttatttgaa tgtgaatagt gtttcaaagg tatgtagtta 2750

 cagaattcct accaaacagc ttaaattctt caagaaagaa ttcctgcagc 2800

 agttattccc ttacctgaag gcttcaatca tttggatcaa caactgctac 2850

 tctcgggaag actcctctac tcacagctga agaaaatgag cacacccttc 2900

 acactgttat tacctatcct gaagatgtga tacactgaat ggaaataaat 2950

 agatgtaaat aaaattgagt tctcatttaa caaaaaaaaa aaaaaaaaaa 3000

<210> 5941
<211> 185
<212> PRT
<213> Homo sapien

<400> 5941
 Met Arg Glu Arg Phe Asp Arg Phe Leu His Glu Lys Asn Cys Met
   1               5                  10                  15

 Thr Asp Leu Leu Ala Lys Leu Glu Ala Lys Thr Gly Val Asn Arg
                  20                  25                  30

 Ser Phe Ile Ala Leu Gly Val Ile Gly Leu Val Ala Leu Tyr Leu
                  35                  40                  45

 Val Phe Gly Tyr Gly Ala Ser Leu Leu Cys Asn Leu Ile Gly Phe
                  50                  55                  60

 Gly Tyr Pro Ala Tyr Ile Ser Ile Lys Ala Ile Glu Ser Pro Asn
                  65                  70                  75

 Lys Glu Asp Asp Thr Gln Trp Leu Thr Tyr Trp Val Val Tyr Gly
                  80                  85                  90

 Val Phe Ser Ile Ala Glu Phe Phe Ser Asp Ile Phe Leu Ser Trp
                  95                 100                 105

 Phe Pro Phe Tyr Tyr Met Leu Lys Cys Gly Phe Leu Leu Trp Cys
                 110                 115                 120

 Met Ala Pro Ser Pro Ser Asn Gly Ala Glu Leu Leu Tyr Lys Arg
                 125                 130                 135

 Ile Ile Arg Pro Phe Phe Leu Lys His Glu Ser Gln Met Asp Ser
                 140                 145                 150

 Val Val Lys Asp Leu Lys Asp Lys Ala Lys Glu Thr Ala Asp Ala
                 155                 160                 165

 Ile Thr Lys Glu Ala Lys Lys Ala Thr Val Asn Leu Leu Gly Glu
                 170                 175                 180

 Glu Lys Lys Ser Thr
                 185

<210> 5942
<211> 1261
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 481
<223> Unknown base

<400> 5942
 gttttcaaac tcatttctaa gccaaatagt ttagataaat atttaccctt 50

 atatttgggg ggaattcagg ctcaccattt gccgaggcaa gcccatcaac 100

 agtctagagg catattctgt gtcattcctt cccgtctcct tcatagaata 150

 ctactttttc cttttgtctc ctggccattc tccatcatct gctgattatt 200

 gctaaccaca ggatgctggc aaagcttaca gtgataggca catgtgttca 250

 gtgatgtcca atacactctt atcacagtgg ttattgcttc ttactctttt 300

 caaatgcatt attctacccc tcaacctaya tccaatcatt agaactatac 350

 ctgactggag cccagaactt gggaccaata cttaattcaa atagcagggg 400

 cttgctcaca aacattaagc ccaamaagaa gcacagcact ttkgaaaagt 450

 caaataggsc tttggtagct ctgtacattt ngcaatttac attgttatta 500

 agtttatagc actaataaca cttcagtcgt gaatctacag tctcaatatg 550

 ataagtctta gaacatgttc tagaaatagt ggtaccttgc tgctattata 600

 cttagtaact tataccccaa tataataata agtattaaat acagattgtg 650

 tatgcattct ttgtgtgtat atgccaactg tactacttaa cctcactgat 700

 gagcaattag aaaaatacac aaattgtcat agtgaaaata agtcttggtc 750

 aattcagatg atacgtgaac ctgataaatg ctctaataga tatgctattt 800

 tgtcctgtat tgcttgtttt acagtatggt gcatgttgtt tgctaagtaa 850

 aatgataata ataataaagt atacccaatt ttaaggttag aattaaaatt 900

 ttgcacatat gcttcttgat attctgaaat gtattctgtg gsttmattat 950

 cttattcata cacattkmgc twggcttttt acccctagga aataactgtc 1000

 caagtatata tctcgtcttc tttcttgtaa ctttgattaa actgcttact 1050

 tcaacttaca acattgtaaa gccagaatac ctcattttaa cagtgaaaaa 1100

 aaatattatg acctgatgtg ttctcttgta tttgatttga actacctaaa 1150

 taggcttaac tgtaataata aatatacaat tttggcaaaa aaaaaaaaaa 1200

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1250

 aaagggcggc c 1261

<210> 5943
<211> 43
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 26
<223> unknown amino acid

<220>
<221> Unsure
<222> 481
<223> Unknown amino acid

<400> 5943
 Met Ser Asn Thr Leu Leu Ser Gln Trp Leu Leu Leu Leu Thr Leu
   1               5                  10                  15

 Phe Lys Cys Ile Ile Leu Pro Leu Asn Leu Xaa Pro Ile Ile Arg
                  20                  25                  30

 Thr Ile Pro Asp Trp Ser Pro Glu Leu Gly Thr Asn Thr
                  35                  40

<210> 5944
<211> 1958
<212> DNA
<213> Homo sapien

<400> 5944
 gggcccgcct cgattttccc aggcgagggc acgcccgcgt cagtcgcctc 50

 cggggcacct tcctcgccac gacacgcagg taaccgggcc ccgggagccg 100

 gtcggcggcg gcggactggg accttgatcc tgcctgcccg gccgcccgac 150

 aagggaatga gagcggaccc cgaactccac acacccgcgt ttagccgcca 200

 cacctaaggg gcagaacagt ctttttgggt aagggccggg ctgggggcga 250

 cgcgccccgc ccgctttgca gacttcgggg tgctctgcac gacgcctgaa 300

 aggccgcggg gcccgcattt ctctgtgctg ccctcctgga gaaccgggac 350

 acggggacgg gagggccagc atcggctacg gcccggtttc ccgtttcttt 400

 cctctgtcgc gtctgggccc tcctgcagcg tccatgatga aggccagggg 450

 ctgttgcttt cctctcgccc agtagccaac ccaagcaagg gaattaatta 500

 tctgaagaaa tggatacttc tccctccaga aaatatccag ttaaaaaacg 550

 ggtgaaaata catcccaaca cagtgatggt gaaatatact tctcattatc 600

 cccagcctgg cgatgatgga tatgaagaaa tcaatgaagg ctatgggaat 650

 tttatggagg aaaatccaaa gaaaggtctg ctgagtgaaa tgaaaaaaaa 700

 agggagagct ttctttggaa ccatggatac cctacctcca ccaacagaag 750

 acccaatgat caatgagatt ggacaattcc agagctttgc agaaaaaaac 800

 atttttcaat cccgaaaaat gtggatagtg ctgtttggat ctgctttggc 850

 tcatggatgt gtagctctta tcactaggct tgtttctgat cggtctaaag 900

 ttccatctct agaactgatt tttatccgtt ctgtttttca ggtcttatct 950

 gtgttagttg tgtgttacta tcaggaggcc ccctttggac ccagtggata 1000

 cagattacga ctcttctttt atggtgtatg caatgtcatt tctatcactt 1050

 gtgcttatac atcattttca atagttcctc ccagcaatgg gaccactatg 1100

 tggagagcca caactacagt cttcagtgcc attttggctt ttttactcgt 1150

 agatgagaaa atggcttatg ttgacatggc tacagttgtt tgcagcatct 1200

 taggtgtttg tcttgtcatg atcccaaaca ttgttgatga agacaattct 1250

 ttgttaaatg cctggaaaga agcctttggg tacaccatga ctgtgatggc 1300

 tggactgacc actgctctct caatgatagt atacagatcc atcaaggaga 1350

 agatcagcat gtggactgcg ctgtttactt ttggttggac tgggacaatt 1400

 tggggaatat ctactatgtt tattcttcaa gaacccatca tcccattaga 1450

 tggagaaacc tggagttatc tcattgctat atgtgtctgt tctactgcag 1500

 cattcttagg agtttattat gccttggaca aattccatcc agctttggtt 1550

 agcacagtac aacatttgga gattgtggta gctatggtct tgcagcttct 1600

 cgtgctgcac atatttccta gcatctatga tgtttttgga ggggtaatca 1650

 ttatgattag tgtttttgtc cttgctggct ataaacttta ctggaggaat 1700

 ttaagaaggc aggactacca ggaaatacta gactctccca ttaaatgaat 1750

 acctgattat tattgtctca ttaatgttca gttattaata tgtatactgc 1800

 cattttaatg tttacctatg aatgtctttt gtgttatata actgacagag 1850

 tgctataaaa tatataatat atacaaatgc agaaaattta ttctagtcta 1900

 atatattcaa atacaaatat taaatatatg aaatacgtta aaaaaaaaaa 1950

 aaaaaaaa 1958

<210> 5945
<211> 412
<212> PRT
<213> Homo sapien

<400> 5945
 Met Asp Thr Ser Pro Ser Arg Lys Tyr Pro Val Lys Lys Arg Val
   1               5                  10                  15

 Lys Ile His Pro Asn Thr Val Met Val Lys Tyr Thr Ser His Tyr
                  20                  25                  30

 Pro Gln Pro Gly Asp Asp Gly Tyr Glu Glu Ile Asn Glu Gly Tyr
                  35                  40                  45

 Gly Asn Phe Met Glu Glu Asn Pro Lys Lys Gly Leu Leu Ser Glu
                  50                  55                  60

 Met Lys Lys Lys Gly Arg Ala Phe Phe Gly Thr Met Asp Thr Leu
                  65                  70                  75

 Pro Pro Pro Thr Glu Asp Pro Met Ile Asn Glu Ile Gly Gln Phe
                  80                  85                  90

 Gln Ser Phe Ala Glu Lys Asn Ile Phe Gln Ser Arg Lys Met Trp
                  95                 100                 105

 Ile Val Leu Phe Gly Ser Ala Leu Ala His Gly Cys Val Ala Leu
                 110                 115                 120

 Ile Thr Arg Leu Val Ser Asp Arg Ser Lys Val Pro Ser Leu Glu
                 125                 130                 135

 Leu Ile Phe Ile Arg Ser Val Phe Gln Val Leu Ser Val Leu Val
                 140                 145                 150

 Val Cys Tyr Tyr Gln Glu Ala Pro Phe Gly Pro Ser Gly Tyr Arg
                 155                 160                 165

 Leu Arg Leu Phe Phe Tyr Gly Val Cys Asn Val Ile Ser Ile Thr
                 170                 175                 180

 Cys Ala Tyr Thr Ser Phe Ser Ile Val Pro Pro Ser Asn Gly Thr
                 185                 190                 195

 Thr Met Trp Arg Ala Thr Thr Thr Val Phe Ser Ala Ile Leu Ala
                 200                 205                 210

 Phe Leu Leu Val Asp Glu Lys Met Ala Tyr Val Asp Met Ala Thr
                 215                 220                 225

 Val Val Cys Ser Ile Leu Gly Val Cys Leu Val Met Ile Pro Asn
                 230                 235                 240

 Ile Val Asp Glu Asp Asn Ser Leu Leu Asn Ala Trp Lys Glu Ala
                 245                 250                 255

 Phe Gly Tyr Thr Met Thr Val Met Ala Gly Leu Thr Thr Ala Leu
                 260                 265                 270

 Ser Met Ile Val Tyr Arg Ser Ile Lys Glu Lys Ile Ser Met Trp
                 275                 280                 285

 Thr Ala Leu Phe Thr Phe Gly Trp Thr Gly Thr Ile Trp Gly Ile
                 290                 295                 300

 Ser Thr Met Phe Ile Leu Gln Glu Pro Ile Ile Pro Leu Asp Gly
                 305                 310                 315

 Glu Thr Trp Ser Tyr Leu Ile Ala Ile Cys Val Cys Ser Thr Ala
                 320                 325                 330

 Ala Phe Leu Gly Val Tyr Tyr Ala Leu Asp Lys Phe His Pro Ala
                 335                 340                 345

 Leu Val Ser Thr Val Gln His Leu Glu Ile Val Val Ala Met Val
                 350                 355                 360

 Leu Gln Leu Leu Val Leu His Ile Phe Pro Ser Ile Tyr Asp Val
                 365                 370                 375

 Phe Gly Gly Val Ile Ile Met Ile Ser Val Phe Val Leu Ala Gly
                 380                 385                 390

 Tyr Lys Leu Tyr Trp Arg Asn Leu Arg Arg Gln Asp Tyr Gln Glu
                 395                 400                 405

 Ile Leu Asp Ser Pro Ile Lys
                 410

<210> 5946
<211> 10742
<212> DNA
<213> Homo sapien

<400> 5946
 caaaaatcag tctgatctcg ggaaacctgg agaaatttat tttctgtact 50

 ctaatgttct ttcattttgg tgaccatcaa ggtgctggga gaggaattag 100

 atggctgtaa ttcaaagtta atggaattag atgcagcagt acagaaattc 150

 ttggaacaga atggccaact gggtaagcca ctggccaaga agataggaaa 200

 actgactgaa cttcaccagc agaccattag acaagctgag aatcggctct 250

 ccaagctcaa tcaggcaaca tcacatttag aagaatacaa tgaaatgctt 300

 gaattaattt tgaagtggat tgaaaaagct aaagtcttgg ctcatggaac 350

 tattgcatgg aattctgcaa gccagcttcg gaaacaatat attttgcatc 400

 agaccctgct agaagaatcc aaagaaattg acagtgagct ggaagcaatg 450

 actgagaaat tacagtacct cactagcgtg tactgtacag aaaaaatgtc 500

 tcagcaagtg gcagaactgg gacgggagac tgaggagttg cgacagatga 550

 tcaaaattcg tttgcagaac ctccaagatg cagctaagga tatgaaaaaa 600

 tttgaagcag agttgaaaaa gttacaagct gccttggagc aagcccaggc 650

 aacactgact tctccagaag ttggacgtct cagtctcaag gagcagctct 700

 ctcatcggca gcatttgttg tctgagatgg agtcactgaa gccgaaggtg 750

 caagcagtgc agctctgcca gagtgccctc cggatccccg aggatgtggt 800

 tgccagctta cctctctgtc atgctgctct gcggctgcag gaagaggcca 850

 gccggctgca gcacaccgcc atccagcagt gtaacatcat gcaggaagct 900

 gtggtacaat atgaacaata tgagcaagaa atgaaacatc tccagcaact 950

 gatagaagga gctcacagag agattgagga taaacctgtt gccaccagta 1000

 acatacagga gctgcaggct cagatttctc ggcatgagga gctggcgcag 1050

 aaaattaagg gctaccagga gcagatcgct tctttgaatt ccaagtgcaa 1100

 gatgctgacg atgaaagcca agcacgccac catgctgctg acggtgaccg 1150

 aggtcgaggg gctggcggaa gggacagagg acctggatgg ggagctcctc 1200

 cccacgcctt cggcccaccc ctctgtggtc atgatgactg caggtcgctg 1250

 tcacactttg ctgtcaccgg tcactgagga gtctggggag gagggaacca 1300

 acagtgagat ttcctctcca cctgcctgtc gctccccttc acctgtggct 1350

 aatacagatg cttctgttaa ccaggacatt gcatattacc aagccttgtc 1400

 tgctgagagg ttgcagacag atgctgcaaa aattcacccc agcacatccg 1450

 catcccagga gttctatgaa ccgggattgg agccatccgc tactgccaaa 1500

 ctgggtgatt tgcagcgttc ttgggaaacc ttaaagaatg tgatcagtga 1550

 gaagcagcgc acactctatg aagctttgga gcgccagcag aagtaccagg 1600

 actccctcca gtccatctct acgaagatgg aggccattga gctgaaactc 1650

 agtgagagcc cagagcctgg caggagtcca gaaagccaga tggctgaaca 1700

 tcaggcattg atggatgaga ttctcatgct ccaggatgaa atcaatgagc 1750

 tccagtcctc tctcgcagag gagctggtat ccgagtcttg tgaggccgac 1800

 cctgcggagc agctggcctt gcagtccacg ctcactgtct tagccgagcg 1850

 aatgtccacc atcaggatga aagcctcggg gaaacggcag cttttggagg 1900

 agaagttgaa tgatcagctg gaggaacaaa ggcaggaaca ggccctgcag 1950

 aggtatcgct gtgaagccga tgagctggac agctggctct tgagtaccaa 2000

 ggccactctg gacactgcgc tgagtccacc caaggagccc atggacatgg 2050

 aggcccagct tatggactgc cagaatatgc tggtggaaat agagcagaag 2100

 gtggtggctt tatcagaact gtcagtccac aatgagaacc tgctgctgga 2150

 gggcaaagct cacaccaagg acgaggccga gcagctggct ggaaagctga 2200

 gaaggctcaa ggggagcctg ctggagctgc agagagccct gcatgataag 2250

 cagctcaaca tgcagggaac agcacaggag aaggaggaga gcgatgttga 2300

 cctaacagcc acgcagagcc ccggcgtcca ggaatggctg gcccaagctc 2350

 gcaccacatg gacccagcag cggcagagca gtctccagca acaaaaagag 2400

 ttagaacagg aattagccga gcagaagagt ctccttcgct cagtagccag 2450

 tcgtggagag gagattctaa ttcaacattc ggcggcagag acctctggtg 2500

 atgctggcga aaaacctgat gtgttatccc aggagttggg gatggaaggg 2550

 gagaaatcat ccgctgaaga ccagatgaga atgaaatggg aaagcctaca 2600

 tcaagaattt agtaccaagc agaaactact acagaatgtt ctggaacagg 2650

 aacaagagca agtgctttat agcaggccaa atcgactctt gtctggtgtg 2700

 ccactgtaca aaggggacgt gccaacccaa gataaatctg cagttacatc 2750

 tttgctggat ggactgaacc aagccttcga ggaggtttca tcccagagtg 2800

 gaggggcaaa gaggcagagt atacacttgg agcagaagtt gtatgatgga 2850

 gtctcagcca cctctacttg gttggatgac gttgaagaac gtttatttgt 2900

 tgccacagca cttttaccag aagaaacaga gacttgtctc ttcaaccaag 2950

 agattcttgc caaagacatt aaggaaatgt ctgaagaaat ggataagaac 3000

 aaaaacttgt tttcccaagc ttttccagag aatggtgata atcgagatgt 3050

 tattgaagat actttgggtt gtcttttggg caggttatcc ttgctagact 3100

 cagtagtgaa tcaacgatgt catcagatga aagaaagact tcagcaaata 3150

 ctaaatttcc agaatgatct gaaagtgctg tttacatcac tggctgacaa 3200

 caaatacatc attctgcaaa aactggcaaa tgtgtttgaa cagcccgtag 3250

 cagaacaaat agaggcaata caacaggctg aagatggact caaagaattt 3300

 gatgcaggaa tcattgaatt aaagaggcgt ggtgacgagc tacaggtcga 3350

 gcagccgtcc atgcaagaac tctccaagct ccaggacatg tatgatgagc 3400

 tgatgatgat cattggctcc cggaggagtg gtctgaatca gaaccttaca 3450

 ctcaagagtc agtatgagag ggccctacaa gatctggctg acctgctaga 3500

 aactggtcag gagaagatgg caggagacca gaaaatcatc gtgtcttcca 3550

 aagaggaaat ccagcaacca cttgacaaac ataaggaata ctttcagggc 3600

 ctggaatctc atatgatctt gactgtaaca ctcttcagaa agataatcag 3650

 ctttgcagtc caaaaggaaa cccagttcca tacagagctg atggctcagg 3700

 cttctgctgt actgaaacgg gctcacaaga ggggtgtgga gctggagtac 3750

 attctagaga cgtggtccca tctggatgag gaccagcagg agctcagcag 3800

 acagctggag gtggtggaaa gcagcatccc aagcgtgggt ctggtggagg 3850

 agaacgagga caggcttatt gaccgcataa cactctacca gcatttaaaa 3900

 tctagcctta atgaatacca gcccaaatta tatcaagtat tagatgatgg 3950

 gaaacgactt ctgatatcca tcagctgctc agatctagaa agccaactaa 4000

 atcaacttgg agagtgctgg ctaagtaaca ccaataaaat gtctaaggaa 4050

 cttcacagac tggaaacaat attgaaacac tggaccagat atcaaagtga 4100

 atctgcagat ctaattcact ggttacaatc tgcaaaagac cggctagaat 4150

 tttggactca gcaatctgtg acagtcccac aagagctgga aatggtccgt 4200

 gatcatctaa atgctttcct ggagttttct aaagaagtgg atgcccaatc 4250

 ttccctgaaa tcatctgttc tgagtactgg aaatcagctc cttcgactaa 4300

 aaaaggtgga cacagccacg ctgcgctctg agttgtcgcg cattgatagc 4350

 cagtggactg acctgctaac caatatccca gccgtccagg agaagctcca 4400

 ccagctccag atggataaac tgccttcccg ccatgccatt tctgaagtca 4450

 tgagttggac ttctctaatg gaaaatgcta ttcagaagga tgaagataat 4500

 attaaaaatt ccataggtta caaggcaatt catgaatacc ttcagaaata 4550

 taagggtttt aagatagaca ttaactgtaa acagctgaca gtggattttg 4600

 tgaaccagtc cgtgctacaa atcagcagtc aggatgtgga aagtaagcgt 4650

 agtgataaga ctgattttgc tgagcaactt ggagcaatga ataaaagttg 4700

 gcaaattctg caaggtctag taactgagaa gatccagctg ttggaaggct 4750

 tattggaatc ttggtcagaa tatgaaaata atgtacaatg tctgaaaaca 4800

 tggtttgaaa cccaggaaaa gagactaaaa caacagcatc gaattggaga 4850

 tcaggcttct gttcaaaatg cactgaaaga ctgtcaggat ctggaagatc 4900

 tgattaaagc aaaagataaa gaagtagaga aaattgagca gaatggactt 4950

 gctttgattc agaccaagaa agaagacgtc tctagcattg tcatgagcac 5000

 actgcgagag ctcggccaaa cctgggcaaa tttagatcac atggttggac 5050

 aattaaagat actgctgaaa tcagtgcttg accaatggag tagtcacaaa 5100

 gtggcctttg acaagataaa cagttacctc atggaggcca gatactctct 5150

 ttcccgattc cgtctgctga ctggctcctt agaagctgtg caagttcagg 5200

 tggacaatct tcagaatctc caagatgatc tggaaaaaca ggaaaggagc 5250

 ttacagaaat ttggctctat caccaaccaa ttattaaaag agtgtcaccc 5300

 acccgtgaca gaaactctta ccaatacact gaaagaagtc aacatgagat 5350

 ggaataactt gctggaagag attgctgagc agctacagtc cagcaaggcc 5400

 ctacttcagc tttggcaaag atacaaggac tactccaaac agtgtgcttc 5450

 gacagttcag cagcaggagg atcgaaccaa tgagctgttg aaggcagcca 5500

 caaacaagga cattgccgat gatgaggttg ccacatggat tcaagattgc 5550

 aacgacctcc tcaaaggact gggcacagtt aaagattccc tctttgttct 5600

 ccatgagctg ggagagcaac tgaagcaaca agtggatgct tccgcagcat 5650

 cagctattca atcggatcaa ctctctttga gtcaacactt gtgtgccctg 5700

 gagcaagctc tctgcaaaca gcagacttca ttacaggctg gagttcttga 5750

 ttatgaaacc tttgccaaga gtttagaagc tttggaggcc tggatagtgg 5800

 aagctgaaga aatactacaa gggcaggacc ctagccactc atctgacctc 5850

 tccacaatcc aggaaaggat ggaagaactt aagggacaga tgttaaaatt 5900

 cagcagcatg gctccagatt tagaccgtct aaatgagctt ggatataggt 5950

 tacccttgaa tgataaggaa atcaaaagaa tgcagaatct gaaccgccat 6000

 tggtctctga tctcctctca gactacagaa agattcagca agttgcagtc 6050

 atttttgcta caacatcaga ctttcttgga aaaatgtgaa acatggatgg 6100

 aattcctagt tcagacagaa caaaagttag cagtagagat ttcaggaaat 6150

 tatcagcacc ttttggaaca gcagagagca cacgagttgt ttcaagccga 6200

 gatgttcagt cgtcagcaga ttttgcactc aatcattatt gatgggcaac 6250

 gtcttctaga acaaggtcaa gttgatgaca gggatgaatt caacctgaaa 6300

 ttgacactcc tcagtaatca atggcaggga gtgattcgca gggcccagca 6350

 gaggcggggg atcattgaca gccagattcg ccagtggcag cgctataggg 6400

 agatggcaga aaagcttcgt aaatggttgg ttgaagtgtc ctacctcccc 6450

 atgagtggtc tcggaagtgt tcctatacca ctgcaacaag caaggaccct 6500

 ctttgatgaa gtgcagttca aagaaaaagt gtttctgcgg caacaaggca 6550

 gctacatcct gactgtggag gctggcaagc aactccttct ctcggcggac 6600

 agtggcgctg aggccgcctt gcaggccgaa ctcgctgaaa tccaagagaa 6650

 atggaaatca gccagcatgc ggctggaaga acagaagaaa aaactagcct 6700

 tcttgttgaa agactgggaa aaatgtgaga aaggaatagc agattccctg 6750

 gagaaactac gaactttcaa aaagaagctt tcgcagtctc tcccggatca 6800

 ccatgaagag ctccatgcag aacaaatgcg ttgcaaggaa ttagaaaatg 6850

 cagttgggag ctggacagat gacttgaccc agttgagcct gctgaaggac 6900

 accctctctg cctatatcag tgctgatgat atctccattc ttaatgaacg 6950

 cgtagagctt ctgcaaaggc agtgggaaga actatgccac cagctctcct 7000

 taaggcggca gcaaataggt gaaagattga atgaatgggc agtcttcagt 7050

 gaaaagaaca aggaactctg tgagtggttg actcaaatgg aaagcaaagt 7100

 ttctcagaat ggagacattc tcattgaaga aatgatagag aagctcaaga 7150

 aggattatca agaggaaatt gctattgctc aagagaacaa aatacagctc 7200

 caacaaatgg gagaacgact tgctaaagcc agccatgaaa gcaaagcatc 7250

 tgagattgaa tacaagctgg gaaaggtcaa cgaccggtgg cagcatctcc 7300

 tggacctcat tgcagccagg gtgaagaagc tgaaggagac cctggtagcc 7350

 gtgcagcagc ttgataagaa catgagcagc ctgaggacct ggctcgctca 7400

 catcgagtca gagctggcca agccaatagt ctacgattcc tgtaactcgg 7450

 aagaaataca gagaaagctt aatgagcagc aggagcttca gagagacata 7500

 gagaagcaca gtacaggtgt tgcatctgtc ctcaacctgt gtgaagtcct 7550

 gctgcacgac tgtgacgcct gtgccactga tgccgagtgt gactctatac 7600

 agcaggctac gagaaacctg gaccggcggt ggagaaacat ttgtgctatg 7650

 tccatggaaa ggaggctgaa aatcgaagag acgtggcgat tgtggcagaa 7700

 atttctggat gactattcac gttttgaaga ttggctgaag tcttcagaaa 7750

 ggacagctgc ttttcccagc tcttctgggg tgatctatac agttgccaag 7800

 gaagaactaa agaaatttga ggctttccag cgacaggtcc acgagtgcct 7850

 gacgcagctg gaactgatca acaagcagta ccgccgcctg gccagggaga 7900

 accgcactga ttcagcatgt agcctcaaac agatggttca cgaaggcaac 7950

 cagagatggg acaacctgca aaagcgtgtc acctccatct tgcgcagact 8000

 caagcatttt attggccagc gtgaggagtt tgagactgcg cgggacagca 8050

 ttctggtctg gctcacagag atggatctgc agctcactaa tattgaacat 8100

 ttttctgagt gtgatgttca agctaaaata aagcaactca aggccttcca 8150

 gcaggaaatt tcactgaacc acaataagat tgagcagata attgcccaag 8200

 gagaacagct gatagaaaag agtgagccct tggatgcagc gatcatcgag 8250

 gaggaactag atgagctccg acggtactgc caggaggtct tcgggcgtgt 8300

 ggaaagatac cataagaaac tgatccgcct gcctctccca gacgatgagc 8350

 acgacctctc agacagggag ctggagctgg aagactctgc agctctgtcg 8400

 gacctgcact ggcacgaccg ctctgcagac agcctgcttt ctccacagcc 8450

 ttcctccaat ctctccctct cgctcgctca gcccctccgg agcgagcggt 8500

 caggacgaga caccccagct agtgtggact ccatccccct ggagtgggat 8550

 cacgactatg acctcagtcg ggacctggag tctgcaatgt ccagagctct 8600

 gccctctgag gatgaagaag gtcaggatga caaagatttc tacctccggg 8650

 gagctgttgc cttatcaggg gaccacagtg ccctagagtc acagatccga 8700

 caactgggca aagccctgga tgatagccgc tttcagatac agcaaaccga 8750

 aaatatcatt cgcagcaaaa ctcccacggg gccggagcta gacaccagct 8800

 acaaaggcta catgaaactg ctgggcgaat gcagtagcag tatagactcc 8850

 gtgaagagac tggagcacaa actgaaggag gaagaggaga gccttcctgg 8900

 ctttgttaac ctgcatagta ccgaaaccca aacggctggt gtgattgacc 8950

 gatgggagct tctccaggcc caggcattga gcaaggagtt gaggatgaag 9000

 cagaacctcc agaagtggca gcagtttaac tcagacttga acagcatctg 9050

 ggcctggctg ggggacacgg aggaggagtt ggaacagctc cagcgtctgg 9100

 aactcagcac tgacatccag accatcgagc tccagatcaa aaagctcaag 9150

 gagctccaga aagctgtgga ccaccgcaaa gccatcatcc tctccatcaa 9200

 tctctgcagc cctgagttca cccaggctga cagcaaggag agccgggacc 9250

 tgcaggatcg cttgtcgcag atgaatgggc gctgggaccg agtgtgctct 9300

 ctgctggagg agtggcgggg cctgctgcag gatgccctga tgcagtgcca 9350

 gggtttccat gaaatgagcc atggtttgct tcttatgctg gagaacattg 9400

 acagaaggaa aaatgaaatt gtccctattg attctaacct tgatgcagag 9450

 atacttcagg accatcacaa acagcttatg caaataaagc atgagctgtt 9500

 ggaatcccaa ctcagagtag cctctttgca agacatgtct tgccaactac 9550

 tggtgaatgc tgaaggaaca gactgtttag aagccaaaga aaaagtccat 9600

 gttattggaa atcggctcaa acttctcttg aaggaggtca gtcgtcatat 9650

 caaggaactg gagaagttat tagacgtgtc aagtagtcag caggatttgt 9700

 cttcctggtc ttctgctgat gaactggaca cctcagggtc tgtgagtccc 9750

 acatcaggaa ggagcacccc aaacagacag aaaacgccac gaggcaagtg 9800

 tagtctctca cagcctggac cctctgtcag cagtccacat agcaggtcca 9850

 caaaaggtgg ctccgattcc tccctttctg agccagggcc aggtcggtcc 9900

 ggccgcggct tcctgttcag agtcctccga gcagctcttc cccttcagct 9950

 tctcctgctc ctcctcatcg ggcttgcctg ccttgtacca atgtcagagg 10000

 aagactacag ctgtgccctc tccaacaact ttgcccggtc attccacccc 10050

 atgctcagat acacgaatgg ccctcctcca ctctgaacta agcagatgcc 10100

 atctgcagaa gtgctggtag cataaggagg atcgggtcat aagcaatccc 10150

 aaactaccaa caagaggacc ttgatcttgg cgaaagccct cggtgtggca 10200

 gctttagccc tcctccagat cacatgtgtg caaattatgg cttcagaggt 10250

 ggaagataaa cagtgacggg ggaacaaaca gacaacaaga aggtttggaa 10300

 gaaatctggt ttgagactct gaaccttagc actaaggaga ttgagtaagg 10350

 acctccaaag ttccccggac tcatgaattc tgggcccttg gcccattctg 10400

 tgcacagcca aggacttcag tagaccatct gggcagcttt cccatggtgc 10450

 tgctccaacc atcagataaa tgaccctccc aagcaccatg tcagtgtcgt 10500

 acaatctacc aaccaaccag tgctgaagag attttagaac cttgtaacat 10550

 acaattttta agagcttata tggcagcttc ctttttacct tgttttcctt 10600

 tggggcatga tgttttaacc tttgctttag aagcacaagc tgtaaatcta 10650

 aaaggcactt ttttttagag gtataaagaa aaactagatg taataaataa 10700

 gatcatggaa ggctttatgt gaaaaaagtt gaatgttata gt 10742

<210> 5947
<211> 3321
<212> PRT
<213> Homo sapien

<400> 5947
 Met Glu Leu Asp Ala Ala Val Gln Lys Phe Leu Glu Gln Asn Gly
   1               5                  10                  15

 Gln Leu Gly Lys Pro Leu Ala Lys Lys Ile Gly Lys Leu Thr Glu
                  20                  25                  30

 Leu His Gln Gln Thr Ile Arg Gln Ala Glu Asn Arg Leu Ser Lys
                  35                  40                  45

 Leu Asn Gln Ala Thr Ser His Leu Glu Glu Tyr Asn Glu Met Leu
                  50                  55                  60

 Glu Leu Ile Leu Lys Trp Ile Glu Lys Ala Lys Val Leu Ala His
                  65                  70                  75

 Gly Thr Ile Ala Trp Asn Ser Ala Ser Gln Leu Arg Lys Gln Tyr
                  80                  85                  90

 Ile Leu His Gln Thr Leu Leu Glu Glu Ser Lys Glu Ile Asp Ser
                  95                 100                 105

 Glu Leu Glu Ala Met Thr Glu Lys Leu Gln Tyr Leu Thr Ser Val
                 110                 115                 120

 Tyr Cys Thr Glu Lys Met Ser Gln Gln Val Ala Glu Leu Gly Arg
                 125                 130                 135

 Glu Thr Glu Glu Leu Arg Gln Met Ile Lys Ile Arg Leu Gln Asn
                 140                 145                 150

 Leu Gln Asp Ala Ala Lys Asp Met Lys Lys Phe Glu Ala Glu Leu
                 155                 160                 165

 Lys Lys Leu Gln Ala Ala Leu Glu Gln Ala Gln Ala Thr Leu Thr
                 170                 175                 180

 Ser Pro Glu Val Gly Arg Leu Ser Leu Lys Glu Gln Leu Ser His
                 185                 190                 195

 Arg Gln His Leu Leu Ser Glu Met Glu Ser Leu Lys Pro Lys Val
                 200                 205                 210

 Gln Ala Val Gln Leu Cys Gln Ser Ala Leu Arg Ile Pro Glu Asp
                 215                 220                 225

 Val Val Ala Ser Leu Pro Leu Cys His Ala Ala Leu Arg Leu Gln
                 230                 235                 240

 Glu Glu Ala Ser Arg Leu Gln His Thr Ala Ile Gln Gln Cys Asn
                 245                 250                 255

 Ile Met Gln Glu Ala Val Val Gln Tyr Glu Gln Tyr Glu Gln Glu
                 260                 265                 270

 Met Lys His Leu Gln Gln Leu Ile Glu Gly Ala His Arg Glu Ile
                 275                 280                 285

 Glu Asp Lys Pro Val Ala Thr Ser Asn Ile Gln Glu Leu Gln Ala
                 290                 295                 300

 Gln Ile Ser Arg His Glu Glu Leu Ala Gln Lys Ile Lys Gly Tyr
                 305                 310                 315

 Gln Glu Gln Ile Ala Ser Leu Asn Ser Lys Cys Lys Met Leu Thr
                 320                 325                 330

 Met Lys Ala Lys His Ala Thr Met Leu Leu Thr Val Thr Glu Val
                 335                 340                 345

 Glu Gly Leu Ala Glu Gly Thr Glu Asp Leu Asp Gly Glu Leu Leu
                 350                 355                 360

 Pro Thr Pro Ser Ala His Pro Ser Val Val Met Met Thr Ala Gly
                 365                 370                 375

 Arg Cys His Thr Leu Leu Ser Pro Val Thr Glu Glu Ser Gly Glu
                 380                 385                 390

 Glu Gly Thr Asn Ser Glu Ile Ser Ser Pro Pro Ala Cys Arg Ser
                 395                 400                 405

 Pro Ser Pro Val Ala Asn Thr Asp Ala Ser Val Asn Gln Asp Ile
                 410                 415                 420

 Ala Tyr Tyr Gln Ala Leu Ser Ala Glu Arg Leu Gln Thr Asp Ala
                 425                 430                 435

 Ala Lys Ile His Pro Ser Thr Ser Ala Ser Gln Glu Phe Tyr Glu
                 440                 445                 450

 Pro Gly Leu Glu Pro Ser Ala Thr Ala Lys Leu Gly Asp Leu Gln
                 455                 460                 465

 Arg Ser Trp Glu Thr Leu Lys Asn Val Ile Ser Glu Lys Gln Arg
                 470                 475                 480

 Thr Leu Tyr Glu Ala Leu Glu Arg Gln Gln Lys Tyr Gln Asp Ser
                 485                 490                 495

 Leu Gln Ser Ile Ser Thr Lys Met Glu Ala Ile Glu Leu Lys Leu
                 500                 505                 510

 Ser Glu Ser Pro Glu Pro Gly Arg Ser Pro Glu Ser Gln Met Ala
                 515                 520                 525

 Glu His Gln Ala Leu Met Asp Glu Ile Leu Met Leu Gln Asp Glu
                 530                 535                 540

 Ile Asn Glu Leu Gln Ser Ser Leu Ala Glu Glu Leu Val Ser Glu
                 545                 550                 555

 Ser Cys Glu Ala Asp Pro Ala Glu Gln Leu Ala Leu Gln Ser Thr
                 560                 565                 570

 Leu Thr Val Leu Ala Glu Arg Met Ser Thr Ile Arg Met Lys Ala
                 575                 580                 585

 Ser Gly Lys Arg Gln Leu Leu Glu Glu Lys Leu Asn Asp Gln Leu
                 590                 595                 600

 Glu Glu Gln Arg Gln Glu Gln Ala Leu Gln Arg Tyr Arg Cys Glu
                 605                 610                 615

 Ala Asp Glu Leu Asp Ser Trp Leu Leu Ser Thr Lys Ala Thr Leu
                 620                 625                 630

 Asp Thr Ala Leu Ser Pro Pro Lys Glu Pro Met Asp Met Glu Ala
                 635                 640                 645

 Gln Leu Met Asp Cys Gln Asn Met Leu Val Glu Ile Glu Gln Lys
                 650                 655                 660

 Val Val Ala Leu Ser Glu Leu Ser Val His Asn Glu Asn Leu Leu
                 665                 670                 675

 Leu Glu Gly Lys Ala His Thr Lys Asp Glu Ala Glu Gln Leu Ala
                 680                 685                 690

 Gly Lys Leu Arg Arg Leu Lys Gly Ser Leu Leu Glu Leu Gln Arg
                 695                 700                 705

 Ala Leu His Asp Lys Gln Leu Asn Met Gln Gly Thr Ala Gln Glu
                 710                 715                 720

 Lys Glu Glu Ser Asp Val Asp Leu Thr Ala Thr Gln Ser Pro Gly
                 725                 730                 735

 Val Gln Glu Trp Leu Ala Gln Ala Arg Thr Thr Trp Thr Gln Gln
                 740                 745                 750

 Arg Gln Ser Ser Leu Gln Gln Gln Lys Glu Leu Glu Gln Glu Leu
                 755                 760                 765

 Ala Glu Gln Lys Ser Leu Leu Arg Ser Val Ala Ser Arg Gly Glu
                 770                 775                 780

 Glu Ile Leu Ile Gln His Ser Ala Ala Glu Thr Ser Gly Asp Ala
                 785                 790                 795

 Gly Glu Lys Pro Asp Val Leu Ser Gln Glu Leu Gly Met Glu Gly
                 800                 805                 810

 Glu Lys Ser Ser Ala Glu Asp Gln Met Arg Met Lys Trp Glu Ser
                 815                 820                 825

 Leu His Gln Glu Phe Ser Thr Lys Gln Lys Leu Leu Gln Asn Val
                 830                 835                 840

 Leu Glu Gln Glu Gln Glu Gln Val Leu Tyr Ser Arg Pro Asn Arg
                 845                 850                 855

 Leu Leu Ser Gly Val Pro Leu Tyr Lys Gly Asp Val Pro Thr Gln
                 860                 865                 870

 Asp Lys Ser Ala Val Thr Ser Leu Leu Asp Gly Leu Asn Gln Ala
                 875                 880                 885

 Phe Glu Glu Val Ser Ser Gln Ser Gly Gly Ala Lys Arg Gln Ser
                 890                 895                 900

 Ile His Leu Glu Gln Lys Leu Tyr Asp Gly Val Ser Ala Thr Ser
                 905                 910                 915

 Thr Trp Leu Asp Asp Val Glu Glu Arg Leu Phe Val Ala Thr Ala
                 920                 925                 930

 Leu Leu Pro Glu Glu Thr Glu Thr Cys Leu Phe Asn Gln Glu Ile
                 935                 940                 945

 Leu Ala Lys Asp Ile Lys Glu Met Ser Glu Glu Met Asp Lys Asn
                 950                 955                 960

 Lys Asn Leu Phe Ser Gln Ala Phe Pro Glu Asn Gly Asp Asn Arg
                 965                 970                 975

 Asp Val Ile Glu Asp Thr Leu Gly Cys Leu Leu Gly Arg Leu Ser
                 980                 985                 990

 Leu Leu Asp Ser Val Val Asn Gln Arg Cys His Gln Met Lys Glu
                 995                1000                1005

 Arg Leu Gln Gln Ile Leu Asn Phe Gln Asn Asp Leu Lys Val Leu
                1010                1015                1020

 Phe Thr Ser Leu Ala Asp Asn Lys Tyr Ile Ile Leu Gln Lys Leu
                1025                1030                1035

 Ala Asn Val Phe Glu Gln Pro Val Ala Glu Gln Ile Glu Ala Ile
                1040                1045                1050

 Gln Gln Ala Glu Asp Gly Leu Lys Glu Phe Asp Ala Gly Ile Ile
                1055                1060                1065

 Glu Leu Lys Arg Arg Gly Asp Glu Leu Gln Val Glu Gln Pro Ser
                1070                1075                1080

 Met Gln Glu Leu Ser Lys Leu Gln Asp Met Tyr Asp Glu Leu Met
                1085                1090                1095

 Met Ile Ile Gly Ser Arg Arg Ser Gly Leu Asn Gln Asn Leu Thr
                1100                1105                1110

 Leu Lys Ser Gln Tyr Glu Arg Ala Leu Gln Asp Leu Ala Asp Leu
                1115                1120                1125

 Leu Glu Thr Gly Gln Glu Lys Met Ala Gly Asp Gln Lys Ile Ile
                1130                1135                1140

 Val Ser Ser Lys Glu Glu Ile Gln Gln Pro Leu Asp Lys His Lys
                1145                1150                1155

 Glu Tyr Phe Gln Gly Leu Glu Ser His Met Ile Leu Thr Val Thr
                1160                1165                1170

 Leu Phe Arg Lys Ile Ile Ser Phe Ala Val Gln Lys Glu Thr Gln
                1175                1180                1185

 Phe His Thr Glu Leu Met Ala Gln Ala Ser Ala Val Leu Lys Arg
                1190                1195                1200

 Ala His Lys Arg Gly Val Glu Leu Glu Tyr Ile Leu Glu Thr Trp
                1205                1210                1215

 Ser His Leu Asp Glu Asp Gln Gln Glu Leu Ser Arg Gln Leu Glu
                1220                1225                1230

 Val Val Glu Ser Ser Ile Pro Ser Val Gly Leu Val Glu Glu Asn
                1235                1240                1245

 Glu Asp Arg Leu Ile Asp Arg Ile Thr Leu Tyr Gln His Leu Lys
                1250                1255                1260

 Ser Ser Leu Asn Glu Tyr Gln Pro Lys Leu Tyr Gln Val Leu Asp
                1265                1270                1275

 Asp Gly Lys Arg Leu Leu Ile Ser Ile Ser Cys Ser Asp Leu Glu
                1280                1285                1290

 Ser Gln Leu Asn Gln Leu Gly Glu Cys Trp Leu Ser Asn Thr Asn
                1295                1300                1305

 Lys Met Ser Lys Glu Leu His Arg Leu Glu Thr Ile Leu Lys His
                1310                1315                1320

 Trp Thr Arg Tyr Gln Ser Glu Ser Ala Asp Leu Ile His Trp Leu
                1325                1330                1335

 Gln Ser Ala Lys Asp Arg Leu Glu Phe Trp Thr Gln Gln Ser Val
                1340                1345                1350

 Thr Val Pro Gln Glu Leu Glu Met Val Arg Asp His Leu Asn Ala
                1355                1360                1365

 Phe Leu Glu Phe Ser Lys Glu Val Asp Ala Gln Ser Ser Leu Lys
                1370                1375                1380

 Ser Ser Val Leu Ser Thr Gly Asn Gln Leu Leu Arg Leu Lys Lys
                1385                1390                1395

 Val Asp Thr Ala Thr Leu Arg Ser Glu Leu Ser Arg Ile Asp Ser
                1400                1405                1410

 Gln Trp Thr Asp Leu Leu Thr Asn Ile Pro Ala Val Gln Glu Lys
                1415                1420                1425

 Leu His Gln Leu Gln Met Asp Lys Leu Pro Ser Arg His Ala Ile
                1430                1435                1440

 Ser Glu Val Met Ser Trp Thr Ser Leu Met Glu Asn Ala Ile Gln
                1445                1450                1455

 Lys Asp Glu Asp Asn Ile Lys Asn Ser Ile Gly Tyr Lys Ala Ile
                1460                1465                1470

 His Glu Tyr Leu Gln Lys Tyr Lys Gly Phe Lys Ile Asp Ile Asn
                1475                1480                1485

 Cys Lys Gln Leu Thr Val Asp Phe Val Asn Gln Ser Val Leu Gln
                1490                1495                1500

 Ile Ser Ser Gln Asp Val Glu Ser Lys Arg Ser Asp Lys Thr Asp
                1505                1510                1515

 Phe Ala Glu Gln Leu Gly Ala Met Asn Lys Ser Trp Gln Ile Leu
                1520                1525                1530

 Gln Gly Leu Val Thr Glu Lys Ile Gln Leu Leu Glu Gly Leu Leu
                1535                1540                1545

 Glu Ser Trp Ser Glu Tyr Glu Asn Asn Val Gln Cys Leu Lys Thr
                1550                1555                1560

 Trp Phe Glu Thr Gln Glu Lys Arg Leu Lys Gln Gln His Arg Ile
                1565                1570                1575

 Gly Asp Gln Ala Ser Val Gln Asn Ala Leu Lys Asp Cys Gln Asp
                1580                1585                1590

 Leu Glu Asp Leu Ile Lys Ala Lys Asp Lys Glu Val Glu Lys Ile
                1595                1600                1605

 Glu Gln Asn Gly Leu Ala Leu Ile Gln Thr Lys Lys Glu Asp Val
                1610                1615                1620

 Ser Ser Ile Val Met Ser Thr Leu Arg Glu Leu Gly Gln Thr Trp
                1625                1630                1635

 Ala Asn Leu Asp His Met Val Gly Gln Leu Lys Ile Leu Leu Lys
                1640                1645                1650

 Ser Val Leu Asp Gln Trp Ser Ser His Lys Val Ala Phe Asp Lys
                1655                1660                1665

 Ile Asn Ser Tyr Leu Met Glu Ala Arg Tyr Ser Leu Ser Arg Phe
                1670                1675                1680

 Arg Leu Leu Thr Gly Ser Leu Glu Ala Val Gln Val Gln Val Asp
                1685                1690                1695

 Asn Leu Gln Asn Leu Gln Asp Asp Leu Glu Lys Gln Glu Arg Ser
                1700                1705                1710

 Leu Gln Lys Phe Gly Ser Ile Thr Asn Gln Leu Leu Lys Glu Cys
                1715                1720                1725

 His Pro Pro Val Thr Glu Thr Leu Thr Asn Thr Leu Lys Glu Val
                1730                1735                1740

 Asn Met Arg Trp Asn Asn Leu Leu Glu Glu Ile Ala Glu Gln Leu
                1745                1750                1755

 Gln Ser Ser Lys Ala Leu Leu Gln Leu Trp Gln Arg Tyr Lys Asp
                1760                1765                1770

 Tyr Ser Lys Gln Cys Ala Ser Thr Val Gln Gln Gln Glu Asp Arg
                1775                1780                1785

 Thr Asn Glu Leu Leu Lys Ala Ala Thr Asn Lys Asp Ile Ala Asp
                1790                1795                1800

 Asp Glu Val Ala Thr Trp Ile Gln Asp Cys Asn Asp Leu Leu Lys
                1805                1810                1815

 Gly Leu Gly Thr Val Lys Asp Ser Leu Phe Val Leu His Glu Leu
                1820                1825                1830

 Gly Glu Gln Leu Lys Gln Gln Val Asp Ala Ser Ala Ala Ser Ala
                1835                1840                1845

 Ile Gln Ser Asp Gln Leu Ser Leu Ser Gln His Leu Cys Ala Leu
                1850                1855                1860

 Glu Gln Ala Leu Cys Lys Gln Gln Thr Ser Leu Gln Ala Gly Val
                1865                1870                1875

 Leu Asp Tyr Glu Thr Phe Ala Lys Ser Leu Glu Ala Leu Glu Ala
                1880                1885                1890

 Trp Ile Val Glu Ala Glu Glu Ile Leu Gln Gly Gln Asp Pro Ser
                1895                1900                1905

 His Ser Ser Asp Leu Ser Thr Ile Gln Glu Arg Met Glu Glu Leu
                1910                1915                1920

 Lys Gly Gln Met Leu Lys Phe Ser Ser Met Ala Pro Asp Leu Asp
                1925                1930                1935

 Arg Leu Asn Glu Leu Gly Tyr Arg Leu Pro Leu Asn Asp Lys Glu
                1940                1945                1950

 Ile Lys Arg Met Gln Asn Leu Asn Arg His Trp Ser Leu Ile Ser
                1955                1960                1965

 Ser Gln Thr Thr Glu Arg Phe Ser Lys Leu Gln Ser Phe Leu Leu
                1970                1975                1980

 Gln His Gln Thr Phe Leu Glu Lys Cys Glu Thr Trp Met Glu Phe
                1985                1990                1995

 Leu Val Gln Thr Glu Gln Lys Leu Ala Val Glu Ile Ser Gly Asn
                2000                2005                2010

 Tyr Gln His Leu Leu Glu Gln Gln Arg Ala His Glu Leu Phe Gln
                2015                2020                2025

 Ala Glu Met Phe Ser Arg Gln Gln Ile Leu His Ser Ile Ile Ile
                2030                2035                2040

 Asp Gly Gln Arg Leu Leu Glu Gln Gly Gln Val Asp Asp Arg Asp
                2045                2050                2055

 Glu Phe Asn Leu Lys Leu Thr Leu Leu Ser Asn Gln Trp Gln Gly
                2060                2065                2070

 Val Ile Arg Arg Ala Gln Gln Arg Arg Gly Ile Ile Asp Ser Gln
                2075                2080                2085

 Ile Arg Gln Trp Gln Arg Tyr Arg Glu Met Ala Glu Lys Leu Arg
                2090                2095                2100

 Lys Trp Leu Val Glu Val Ser Tyr Leu Pro Met Ser Gly Leu Gly
                2105                2110                2115

 Ser Val Pro Ile Pro Leu Gln Gln Ala Arg Thr Leu Phe Asp Glu
                2120                2125                2130

 Val Gln Phe Lys Glu Lys Val Phe Leu Arg Gln Gln Gly Ser Tyr
                2135                2140                2145

 Ile Leu Thr Val Glu Ala Gly Lys Gln Leu Leu Leu Ser Ala Asp
                2150                2155                2160

 Ser Gly Ala Glu Ala Ala Leu Gln Ala Glu Leu Ala Glu Ile Gln
                2165                2170                2175

 Glu Lys Trp Lys Ser Ala Ser Met Arg Leu Glu Glu Gln Lys Lys
                2180                2185                2190

 Lys Leu Ala Phe Leu Leu Lys Asp Trp Glu Lys Cys Glu Lys Gly
                2195                2200                2205

 Ile Ala Asp Ser Leu Glu Lys Leu Arg Thr Phe Lys Lys Lys Leu
                2210                2215                2220

 Ser Gln Ser Leu Pro Asp His His Glu Glu Leu His Ala Glu Gln
                2225                2230                2235

 Met Arg Cys Lys Glu Leu Glu Asn Ala Val Gly Ser Trp Thr Asp
                2240                2245                2250

 Asp Leu Thr Gln Leu Ser Leu Leu Lys Asp Thr Leu Ser Ala Tyr
                2255                2260                2265

 Ile Ser Ala Asp Asp Ile Ser Ile Leu Asn Glu Arg Val Glu Leu
                2270                2275                2280

 Leu Gln Arg Gln Trp Glu Glu Leu Cys His Gln Leu Ser Leu Arg
                2285                2290                2295

 Arg Gln Gln Ile Gly Glu Arg Leu Asn Glu Trp Ala Val Phe Ser
                2300                2305                2310

 Glu Lys Asn Lys Glu Leu Cys Glu Trp Leu Thr Gln Met Glu Ser
                2315                2320                2325

 Lys Val Ser Gln Asn Gly Asp Ile Leu Ile Glu Glu Met Ile Glu
                2330                2335                2340

 Lys Leu Lys Lys Asp Tyr Gln Glu Glu Ile Ala Ile Ala Gln Glu
                2345                2350                2355

 Asn Lys Ile Gln Leu Gln Gln Met Gly Glu Arg Leu Ala Lys Ala
                2360                2365                2370

 Ser His Glu Ser Lys Ala Ser Glu Ile Glu Tyr Lys Leu Gly Lys
                2375                2380                2385

 Val Asn Asp Arg Trp Gln His Leu Leu Asp Leu Ile Ala Ala Arg
                2390                2395                2400

 Val Lys Lys Leu Lys Glu Thr Leu Val Ala Val Gln Gln Leu Asp
                2405                2410                2415

 Lys Asn Met Ser Ser Leu Arg Thr Trp Leu Ala His Ile Glu Ser
                2420                2425                2430

 Glu Leu Ala Lys Pro Ile Val Tyr Asp Ser Cys Asn Ser Glu Glu
                2435                2440                2445

 Ile Gln Arg Lys Leu Asn Glu Gln Gln Glu Leu Gln Arg Asp Ile
                2450                2455                2460

 Glu Lys His Ser Thr Gly Val Ala Ser Val Leu Asn Leu Cys Glu
                2465                2470                2475

 Val Leu Leu His Asp Cys Asp Ala Cys Ala Thr Asp Ala Glu Cys
                2480                2485                2490

 Asp Ser Ile Gln Gln Ala Thr Arg Asn Leu Asp Arg Arg Trp Arg
                2495                2500                2505

 Asn Ile Cys Ala Met Ser Met Glu Arg Arg Leu Lys Ile Glu Glu
                2510                2515                2520

 Thr Trp Arg Leu Trp Gln Lys Phe Leu Asp Asp Tyr Ser Arg Phe
                2525                2530                2535

 Glu Asp Trp Leu Lys Ser Ser Glu Arg Thr Ala Ala Phe Pro Ser
                2540                2545                2550

 Ser Ser Gly Val Ile Tyr Thr Val Ala Lys Glu Glu Leu Lys Lys
                2555                2560                2565

 Phe Glu Ala Phe Gln Arg Gln Val His Glu Cys Leu Thr Gln Leu
                2570                2575                2580

 Glu Leu Ile Asn Lys Gln Tyr Arg Arg Leu Ala Arg Glu Asn Arg
                2585                2590                2595

 Thr Asp Ser Ala Cys Ser Leu Lys Gln Met Val His Glu Gly Asn
                2600                2605                2610

 Gln Arg Trp Asp Asn Leu Gln Lys Arg Val Thr Ser Ile Leu Arg
                2615                2620                2625

 Arg Leu Lys His Phe Ile Gly Gln Arg Glu Glu Phe Glu Thr Ala
                2630                2635                2640

 Arg Asp Ser Ile Leu Val Trp Leu Thr Glu Met Asp Leu Gln Leu
                2645                2650                2655

 Thr Asn Ile Glu His Phe Ser Glu Cys Asp Val Gln Ala Lys Ile
                2660                2665                2670

 Lys Gln Leu Lys Ala Phe Gln Gln Glu Ile Ser Leu Asn His Asn
                2675                2680                2685

 Lys Ile Glu Gln Ile Ile Ala Gln Gly Glu Gln Leu Ile Glu Lys
                2690                2695                2700

 Ser Glu Pro Leu Asp Ala Ala Ile Ile Glu Glu Glu Leu Asp Glu
                2705                2710                2715

 Leu Arg Arg Tyr Cys Gln Glu Val Phe Gly Arg Val Glu Arg Tyr
                2720                2725                2730

 His Lys Lys Leu Ile Arg Leu Pro Leu Pro Asp Asp Glu His Asp
                2735                2740                2745

 Leu Ser Asp Arg Glu Leu Glu Leu Glu Asp Ser Ala Ala Leu Ser
                2750                2755                2760

 Asp Leu His Trp His Asp Arg Ser Ala Asp Ser Leu Leu Ser Pro
                2765                2770                2775

 Gln Pro Ser Ser Asn Leu Ser Leu Ser Leu Ala Gln Pro Leu Arg
                2780                2785                2790

 Ser Glu Arg Ser Gly Arg Asp Thr Pro Ala Ser Val Asp Ser Ile
                2795                2800                2805

 Pro Leu Glu Trp Asp His Asp Tyr Asp Leu Ser Arg Asp Leu Glu
                2810                2815                2820

 Ser Ala Met Ser Arg Ala Leu Pro Ser Glu Asp Glu Glu Gly Gln
                2825                2830                2835

 Asp Asp Lys Asp Phe Tyr Leu Arg Gly Ala Val Ala Leu Ser Gly
                2840                2845                2850

 Asp His Ser Ala Leu Glu Ser Gln Ile Arg Gln Leu Gly Lys Ala
                2855                2860                2865

 Leu Asp Asp Ser Arg Phe Gln Ile Gln Gln Thr Glu Asn Ile Ile
                2870                2875                2880

 Arg Ser Lys Thr Pro Thr Gly Pro Glu Leu Asp Thr Ser Tyr Lys
                2885                2890                2895

 Gly Tyr Met Lys Leu Leu Gly Glu Cys Ser Ser Ser Ile Asp Ser
                2900                2905                2910

 Val Lys Arg Leu Glu His Lys Leu Lys Glu Glu Glu Glu Ser Leu
                2915                2920                2925

 Pro Gly Phe Val Asn Leu His Ser Thr Glu Thr Gln Thr Ala Gly
                2930                2935                2940

 Val Ile Asp Arg Trp Glu Leu Leu Gln Ala Gln Ala Leu Ser Lys
                2945                2950                2955

 Glu Leu Arg Met Lys Gln Asn Leu Gln Lys Trp Gln Gln Phe Asn
                2960                2965                2970

 Ser Asp Leu Asn Ser Ile Trp Ala Trp Leu Gly Asp Thr Glu Glu
                2975                2980                2985

 Glu Leu Glu Gln Leu Gln Arg Leu Glu Leu Ser Thr Asp Ile Gln
                2990                2995                3000

 Thr Ile Glu Leu Gln Ile Lys Lys Leu Lys Glu Leu Gln Lys Ala
                3005                3010                3015

 Val Asp His Arg Lys Ala Ile Ile Leu Ser Ile Asn Leu Cys Ser
                3020                3025                3030

 Pro Glu Phe Thr Gln Ala Asp Ser Lys Glu Ser Arg Asp Leu Gln
                3035                3040                3045

 Asp Arg Leu Ser Gln Met Asn Gly Arg Trp Asp Arg Val Cys Ser
                3050                3055                3060

 Leu Leu Glu Glu Trp Arg Gly Leu Leu Gln Asp Ala Leu Met Gln
                3065                3070                3075

 Cys Gln Gly Phe His Glu Met Ser His Gly Leu Leu Leu Met Leu
                3080                3085                3090

 Glu Asn Ile Asp Arg Arg Lys Asn Glu Ile Val Pro Ile Asp Ser
                3095                3100                3105

 Asn Leu Asp Ala Glu Ile Leu Gln Asp His His Lys Gln Leu Met
                3110                3115                3120

 Gln Ile Lys His Glu Leu Leu Glu Ser Gln Leu Arg Val Ala Ser
                3125                3130                3135

 Leu Gln Asp Met Ser Cys Gln Leu Leu Val Asn Ala Glu Gly Thr
                3140                3145                3150

 Asp Cys Leu Glu Ala Lys Glu Lys Val His Val Ile Gly Asn Arg
                3155                3160                3165

 Leu Lys Leu Leu Leu Lys Glu Val Ser Arg His Ile Lys Glu Leu
                3170                3175                3180

 Glu Lys Leu Leu Asp Val Ser Ser Ser Gln Gln Asp Leu Ser Ser
                3185                3190                3195

 Trp Ser Ser Ala Asp Glu Leu Asp Thr Ser Gly Ser Val Ser Pro
                3200                3205                3210

 Thr Ser Gly Arg Ser Thr Pro Asn Arg Gln Lys Thr Pro Arg Gly
                3215                3220                3225

 Lys Cys Ser Leu Ser Gln Pro Gly Pro Ser Val Ser Ser Pro His
                3230                3235                3240

 Ser Arg Ser Thr Lys Gly Gly Ser Asp Ser Ser Leu Ser Glu Pro
                3245                3250                3255

 Gly Pro Gly Arg Ser Gly Arg Gly Phe Leu Phe Arg Val Leu Arg
                3260                3265                3270

 Ala Ala Leu Pro Leu Gln Leu Leu Leu Leu Leu Leu Ile Gly Leu
                3275                3280                3285

 Ala Cys Leu Val Pro Met Ser Glu Glu Asp Tyr Ser Cys Ala Leu
                3290                3295                3300

 Ser Asn Asn Phe Ala Arg Ser Phe His Pro Met Leu Arg Tyr Thr
                3305                3310                3315

 Asn Gly Pro Pro Pro Leu
                3320

<210> 5948
<211> 1116
<212> DNA
<213> Homo sapien

<400> 5948
 gtgtgaggcc atcacggaag atgctgctgc ttctgctgct tctggggcta 50

 gcaggctccg ggcttggtgc tgtcgtctct caacatccga gctgggttat 100

 ctgtaagagt ggaacctctg tgaagatcga gtgccgttcc ctggactttc 150

 aggccacaac tatgttttgg tatcgtcagt tcccgaaaca gagtctcatg 200

 ctgatggcaa cttccaatga gggctccaag gccacatacg agcaaggcgt 250

 cgagaaggac aagtttctca tcaaccatgc aagcctgacc ttgtccactc 300

 tgacagtgac cagtgcccat cctgaagaca gcagcttcta catctgcagt 350

 gctagagagt cgactagcga tccaaaaaat gagcagttct tcgggccagg 400

 gacacggctc accgtgctag aggacctgaa aaacgtgttc ccacccgagg 450

 tcgctgtgtt tgagccatca gaagcagaga tctcccacac ccaaaaggcc 500

 acactggtgt gcctggccac aggcttctac cccgaccacg tggagctgag 550

 ctggtgggtg aatgggaagg aggtgcacag tggggtcagc acagacccgc 600

 agcccctcaa ggagcagccc gccctcaatg actccagata ctgcctgagc 650

 agccgcctga gggtctcggc caccttctgg cagaaccccc gcaaccactt 700

 ccgctgtcaa gtccagttct acgggctctc ggagaatgac gagtggaccc 750

 aggatagggc caaacctgtc acccagatcg tcagcgccga ggcctggggt 800

 agagcagact gtggcttcac ctccgagtct taccagcaag gggtcctgtc 850

 tgccaccatc ctctatgaga tcttgctagg gaaggccacc ttgtatgccg 900

 tgctggtcag tgccctcgtg ctgatggcca tggtcaagag aaaggattcc 950

 agaggctagc tccaaaacca tcccaggtca ttcttcatcc tcacccagga 1000

 ttctcctgta cctgctccca atctgtgttc ctaaaagtga ttctcactct 1050

 gcttctcatc tcctacttac atgaatactt ctctcttttt tctgtttccc 1100

 tgaagattga gctccc 1116

<210> 5949
<211> 312
<212> PRT
<213> Homo sapien

<400> 5949
 Met Leu Leu Leu Leu Leu Leu Leu Gly Leu Ala Gly Ser Gly Leu
   1               5                  10                  15

 Gly Ala Val Val Ser Gln His Pro Ser Trp Val Ile Cys Lys Ser
                  20                  25                  30

 Gly Thr Ser Val Lys Ile Glu Cys Arg Ser Leu Asp Phe Gln Ala
                  35                  40                  45

 Thr Thr Met Phe Trp Tyr Arg Gln Phe Pro Lys Gln Ser Leu Met
                  50                  55                  60

 Leu Met Ala Thr Ser Asn Glu Gly Ser Lys Ala Thr Tyr Glu Gln
                  65                  70                  75

 Gly Val Glu Lys Asp Lys Phe Leu Ile Asn His Ala Ser Leu Thr
                  80                  85                  90

 Leu Ser Thr Leu Thr Val Thr Ser Ala His Pro Glu Asp Ser Ser
                  95                 100                 105

 Phe Tyr Ile Cys Ser Ala Arg Glu Ser Thr Ser Asp Pro Lys Asn
                 110                 115                 120

 Glu Gln Phe Phe Gly Pro Gly Thr Arg Leu Thr Val Leu Glu Asp
                 125                 130                 135

 Leu Lys Asn Val Phe Pro Pro Glu Val Ala Val Phe Glu Pro Ser
                 140                 145                 150

 Glu Ala Glu Ile Ser His Thr Gln Lys Ala Thr Leu Val Cys Leu
                 155                 160                 165

 Ala Thr Gly Phe Tyr Pro Asp His Val Glu Leu Ser Trp Trp Val
                 170                 175                 180

 Asn Gly Lys Glu Val His Ser Gly Val Ser Thr Asp Pro Gln Pro
                 185                 190                 195

 Leu Lys Glu Gln Pro Ala Leu Asn Asp Ser Arg Tyr Cys Leu Ser
                 200                 205                 210

 Ser Arg Leu Arg Val Ser Ala Thr Phe Trp Gln Asn Pro Arg Asn
                 215                 220                 225

 His Phe Arg Cys Gln Val Gln Phe Tyr Gly Leu Ser Glu Asn Asp
                 230                 235                 240

 Glu Trp Thr Gln Asp Arg Ala Lys Pro Val Thr Gln Ile Val Ser
                 245                 250                 255

 Ala Glu Ala Trp Gly Arg Ala Asp Cys Gly Phe Thr Ser Glu Ser
                 260                 265                 270

 Tyr Gln Gln Gly Val Leu Ser Ala Thr Ile Leu Tyr Glu Ile Leu
                 275                 280                 285

 Leu Gly Lys Ala Thr Leu Tyr Ala Val Leu Val Ser Ala Leu Val
                 290                 295                 300

 Leu Met Ala Met Val Lys Arg Lys Asp Ser Arg Gly
                 305                 310

<210> 5950
<211> 10709
<212> DNA
<213> Homo sapien

<400> 5950
 agggggcggc gctcccggcc catcccttag ccccgcggcg gccgtgtggg 50

 ccggaggctg cctgcaccgc gtcagggagg ccggcctaga aaccctccct 100

 cccagaagaa agccgatccc agttcaggtg gggtcttcct cggttgcgta 150

 cctggctgga gccgagctgg tgggcggccg gcagccggcg tttctggtga 200

 tgacagcccc gaaatgaaag cagcgcggcc gccgcctccg agggctgcag 250

 ggagatcagc gtccagcaaa taagaagcaa gtcctggacc cggaggagga 300

 ggagcggccg agcatctctc tctgctccgc cgtgtccttt agatgagcac 350

 tcccggccgg agccggaggt ggatccgcag agctgcctct gggcgcctga 400

 ccccgcgctg acatcacaac ctgtgacagg cgcatcacgc ccggtacctg 450

 ctcccggccg ctgcccgtcc tcccagcctc tttgtatgcc gcagacatgg 500

 ccagccagca ggattcgggc ttctttgaga tcagtatcaa atatttactg 550

 aaatcctgga gtaatacttc tcccgttggc aacggttaca tcaagcctcc 600

 ggttccacct gcttctggca cgcacaggga gaaagggccg ccaaccatgc 650

 tacccatcaa tgtggaccca gacagtaaac caggagaata tgtcctcaaa 700

 agtttatttg tcaacttcac cactcaggct gaacgcaaga ttcgtatcat 750

 tatggcagag cccctggaaa agccattgac gaaatctctg caacgtggag 800

 aagaccccca atttgatcag gtcatcagct caatgagctc cctttctgag 850

 tactgcctgc cttccattct acgtacatta tttgactggt ataaaaggca 900

 aaatggcatt gaggatgaat cacatgaata cagaccaaga acaagcaata 950

 aatcaaaaag cgatgaacaa cagcgagatt atttaatgga aagacgggac 1000

 ctcgccattg attttatttt ttctttagta ttaatagaag ttttgaaaca 1050

 gattccactt catcctgtaa tagacagttt aatacatgat gttattaact 1100

 tggctttcaa gcactttaaa tacaaagaag ggtaccttgg tcccaacact 1150

 ggcaatatgc atattgtggc agacctgtat gcagaagtca ttggagtgtt 1200

 ggcacaagcc aaattccctg ctgtaaagaa gaaatttatg gcggagctaa 1250

 aagaattacg gcacaaagag cagaacccat atgtggttca aagcattatc 1300

 agcttaataa tgggcatgaa attctttcga attaagatgt atccagtgga 1350

 ggattttgag gcctctcttc agtttatgca ggaatgtgca cattacttcc 1400

 tcgaggtcaa agacaaagat atcaagcatg ccttggctgg gctttttgtt 1450

 gaaatacttg ttccagttgc tgctgctgtt aaaaatgaag taaatgttcc 1500

 ctgccttaga aattttgtgg aaagcctgta tgacaccacg ctggaacttt 1550

 cttctcgaaa gaagcattcc ttggccttgt accccctggt gacctgtttg 1600

 ctctgtgtca gtcagaagca gctgttcctg aacaggtggc acattttcct 1650

 caacaactgc ttgtccaacc ttaaaaacaa agatcccaag atggctcgag 1700

 ttgcactgga atctctctac agattacttt gggtttacat gattcgaatt 1750

 aaatgtgaaa gcaacacagc tactcagagc cgacttataa ccatcatcac 1800

 aacacttttc cccaaagggt cccgcggtgt ggtaccaagg gacatgcctc 1850

 tgaacatctt tgtgaaaatc atccagttca ttgcccagga acgtttagat 1900

 tttgcaatga aagaaatcat tttcgatttt ctttgtgtgg gaaaaccagc 1950

 aaaagcattc agtctcaacc cagagagaat gaacattggt ttacgggcat 2000

 tcttggtcat agctgatagc ttgcagcaga aagatgggga acctcccatg 2050

 ccggttacag gagccgttct tccttcagga aacacgttaa gagtaaagaa 2100

 aacatatttg agtaaaacac taactgaaga ggaagccaaa atgataggca 2150

 tgtccttata ttactctcaa gtacgaaaag ctgtagacaa cattttaagg 2200

 caccttgata aagaagtagg aaggtgtatg atgctgacta atgtacagat 2250

 gttaaacaaa gaaccggaag acatgatcac gggtgagaga aagccaaaaa 2300

 tagatctttt caggacctgt gttgctgcta ttcctcgact gcttcctgat 2350

 gggatgtcaa aacttgaact tattgactta ctggctaggc tctctattca 2400

 tatggatgat gaattgcgac atattgcaca aaattctctt cagggtttac 2450

 ttgttgactt ctcagattgg agggaagatg tactatttgg ctttaccaac 2500

 ttcctgctcc gggaagtaaa tgatatgcat cacacactcc ttgattcgtc 2550

 cctgaagttg ctgctgcagc tgctcaccca gtggaaacta gtcatccaga 2600

 cacaaggaaa agtctatgaa caagccaaca aaatcagaaa ttcagagctc 2650

 atcgcaaatg gctccagtca cagaattcag tcggaacgag gtccccactg 2700

 cagtgtactc cacgctgtag aaggttttgc tctggtttta ctctgcagtt 2750

 tccaggtggc cacacgcaaa ctgtccgttt taatactcaa ggaaattcga 2800

 gcgttgttta ttgccctggg gcagcctgag gatgacgaca ggccgatgat 2850

 tgatgtcatg gatcagctaa gttcttccat tctagaaagt tttattcatg 2900

 tagcagtttc ggattcagca acattaccac tcacccacaa tgtggatctg 2950

 cagtggttgg tggaatggaa cgcagtcctg gtcaatagcc attatgatgt 3000

 gaaaagccct tcccatgtct ggatatttgc acagtctgtc aaagacccct 3050

 gggtcctctg cctcttcagc ttcctccggc aggagaactt acccaagcac 3100

 tgccccacag ccctcagcta tgcctggcct tatgccttca ctcggctcca 3150

 gtcggtgatg cctctggtgg acccaaatag cccaattaat gccaagaaaa 3200

 ccagcactgc cggcagcgga gacaactatg ttactttgtg gagaaattac 3250

 ctaattcttt gttttggagt tgcaaaaccc agtattatga gcccaggaca 3300

 cttaagagct tccactccag aaataatggc gaccacacct gatggtacag 3350

 tgagctacga taacaaggcc ataggcaccc catcggtggg agttctgtta 3400

 aagcagttgg tgcctttgat gagactagag agcattgaga tcacagagtc 3450

 cttagtttta ggatttggaa gaacaaattc ccttgttttc agagaattgg 3500

 tagaagaact tcatccatta atgaaagaag ctctggaaag aagaccagag 3550

 aacaagaaac gccgagaacg gcgagacttg ttaaggctac aactacttcg 3600

 aatttttgaa cttttggctg atgctggtgt aataagtgac agcacaaatg 3650

 gagccctaga gcgggatact ttagccctgg gagctttgtt cttagaatat 3700

 gtggacttga cccgcatgct cctagaagct gaaaatgaca aagaagttga 3750

 aattcttaaa gatatccggg cacattttag tgcaatggtg gccaacttga 3800

 ttcagtgtgt tccagttcac caccgaagat ttctcttccc ccagcaaagt 3850

 ctgaggcacc accttttcat cttattcagc cagtgggcag gacccttcag 3900

 cattatgttc actcctctgg atcgttacag tgacagaaat catcagatta 3950

 caagatatca gtattgtgca ttaaaagcaa tgtcagcagt actgtgctgt 4000

 ggccctgtct ttgacaatgt gggcctttcc ccagatggct acctatataa 4050

 atggcttgac aacattctgg cttgtcaaga tttacgagtt catcaacttg 4100

 gctgcgaagt tgttgtcttg ctactggaac ttaatcctga ccaaataaat 4150

 ctttttaact gggcaattga ccgatgctac acaggttcct accaacttgc 4200

 atctggctgc ttcaaagcca tagcaactgt gtgtggaagc aggaactatc 4250

 ccttcgacat agtgacattg ttaaaccttg ttctattcaa ggcctctgac 4300

 accaacagag agatttatga aatctccatg cagctcatgc agatccttga 4350

 agcaaagctt tttgtatact caaagaaagt cgctgagcaa agaccgggaa 4400

 gtattctcta tggaacacac ggcccgctgc cacccctcta cagcgtgtca 4450

 ctcgccctct tgtcatgtga gctggccagg atgtaccctg agctcacact 4500

 ccccctcttc tcaggtaagc cagcgattcc ccacaacaca ccccaacggg 4550

 cgccagatca tgcttaccta cctgctgccc tggctgcaca acatcgagct 4600

 ggtggacagc aggctcctcc tcccgggtcg agccccagca gcccagagga 4650

 cgaagtcaag gaccgggaag gtgacgtgac tgcttctcac gggctgagag 4700

 gaaatggctg gggctctcca gaagccacgt cactggtcct gaacaacctc 4750

 atgtacatga cggccaagta tggagatgaa gttcctgggc cagaaatgga 4800

 aaatgcttgg aatgctttag ccaacaatga gaaatggagc aacaacctga 4850

 ggatcacctt gcagttcctg attagcctct gtggggtcag cagcgacaca 4900

 gttctcctac cctatattaa aaaagtggca atatacttgt gccgtaacaa 4950

 caccattcaa accatggaag agcttctctt tgagctgcag cagacagaac 5000

 ccgtgaaccc catcgtccag cattgtgaca acccgccctt ctaccgcttc 5050

 acggccagta gcaaggcttc cgcagcagcc tcaggaacca cctctagcag 5100

 caatacagtg gttgctggcc aggaaaattt cccagatgct gaggagaaca 5150

 agatattgaa agaatctgat gaaaggttta gtaatgtcat cagagcccac 5200

 actcgcctcg agtcaagata cagcaatagc tctggaggat cctacgatga 5250

 agataaaaat gatccaattt ctccctacac gggctggttg ctgactatta 5300

 cagagaccaa gcagccgcag cccttaccga tgccttgtac tggaggatgc 5350

 tgggcccccc tggttgacta tctcccggag accatcactc cccgggggcc 5400

 actccacagg tgcaatattg ctgtaatttt tatgactgaa atggtggtgg 5450

 atcacagtgt acgagaagac tgggcgcttc atctaccatt attacttcat 5500

 gctgtcttct taggtttaga ccactaccgg cctgaagtct ttgaacacag 5550

 caaaaaactg cttcttcacc tcttgattgc cctctcttgc aacagcaatt 5600

 tccattccat tgcttccgtg ctcctgcaga cccgagagat gggtgaagct 5650

 aagactctaa ccgtgcagcc agcctaccaa cctgaatatc tctatacagg 5700

 tggctttgac ttcctgagag aggaccagtc atccccggtg cctgactcag 5750

 ggcttagttc aagctccacc tcctctagca tcagtctggg aggcagcagt 5800

 ggaaacctcc cacagatgac ccaggaggta gaagatgtgg acacagctgc 5850

 tgaaacagat gagaaggcaa acaagctcat tgagtttctc acgaccaggg 5900

 catttggtcc actttggtgc catgaagaca tcacacctaa aaatcaaaat 5950

 tcaaagagtg ctgaacagct cactaatttt ctacgtcacg ttgtatctgt 6000

 atttaaagat tccaaatcag gcttccatct ggagcaccag ttgagtgaag 6050

 ttgcattgca gacagccctc gcaagctctt caaggcacta tgctggtcgg 6100

 tccttccaga tattccgggc cctcaagcaa cctctgtcag cacatgcctt 6150

 atctgacctt ctctcaagat tggtggaggt gataggagaa catggagatg 6200

 agattcaggg ttatgtaatg gaagcgctcc taaccttgga ggcggctgtg 6250

 gataacttgt ctgactgctt gaagaacagt gacctcctaa ctgtattgtc 6300

 ccgctcttcc tcaccagatt taagctccag cagtaaacta acagcaagca 6350

 gaaagagcac aggacaacta aacatgaacc cgggaaccac cagcggcaac 6400

 accgcaactg ccgaacggag ccggcatcaa cgaagcttct ctgtgcccaa 6450

 gaagtttggt gtcatcgacc gatcctctga cccacctcga agtgccacac 6500

 tggacagaat tcaggcttgt acccaacaag gcctctcctc aaaaaccaga 6550

 agctcatcct ccttgaagga cagtctcacg gacccatccc acataaacca 6600

 tcccaccaac ctgctggcca ccatattctg ggtcacagtg gccttgatgg 6650

 agtctgattt tgagtttgaa tacttaatgg ccttaaggct gttgagcaga 6700

 ctactggcac atatgccact cgataaggct gagaaccgag aaaagcttga 6750

 gaaactccag gcacagctga agtgggccga cttctccggg ctgcagcagc 6800

 tgctgctgaa aggattcaca tccctcacca ccacagacct gaccctgcag 6850

 ctcttcagtc tgctgacacc agtgtccaaa atatccatgg tggatgcatc 6900

 ccacgctatt gggtttccac tgaatgtctt gtgtctcctg cctcagctga 6950

 ttcagcattt tgaaaatccc aatcagttct gtaaggatat agccgaaagg 7000

 attgctcagg tttgtttaga agagaagaac cccaaacttt caaatcttgc 7050

 acatgtcatg actctttata aaacgcacag ctacacgagg gactgtgcca 7100

 cgtgggtcaa tgtggtctgt cgataccttc atgaagcata tgctgacatt 7150

 accttgaata tggttaccta cctggcagag ctgctggaga agggcctccc 7200

 tagtgtgcag cagcccctgc tccaggtgat ctacagtctt ctcagctaca 7250

 tggacctttc tgtcgttcct gtcaaacagt tcaatgtgga agttctgaag 7300

 acaattgaaa aatatgtgca aagtgttcac tggagagaag ctctgaatat 7350

 cttgaagctg gtagtttctc ggtcagccag ccttgtttta ccttcatacc 7400

 agcacagtga cctctcaaaa atagaaatac atcgagtgtg gactagtgct 7450

 tccaaggaat tacctgggaa aaccctggac ttccacttcg atatttcgga 7500

 gactccaatc atcgggaggc ggtatgatga gctgcagaat tcttctgggc 7550

 gtgatgggaa gcccagggcc atggccgtca cccggagcac atcttccact 7600

 tcctcaggct ccaactccaa cgtccttgtt ccagtgagct ggaaaaggcc 7650

 ccagtattct cagaagagaa caaaagagaa gttggtacat gtcctttctc 7700

 tgtgtggcca agaagtagga ttgagcaaaa atccatcagt gattttttca 7750

 tcgtgtgggg atctggatct gcttgagcac cagacaagct tggtatcttc 7800

 tgaggacggt gcccgagagc aggagaacat ggatgacaca aacagcgagc 7850

 agcagtttag agtcttcaga gacttcgact tcctagatgt ggagctggag 7900

 gatggagagg gtgagagtat ggacaatttc aactggggag tgcgcagacg 7950

 ttctctggac agcctggata agtgtgatat gcagattctg gaggagcgcc 8000

 aactgtcagg aagcactcct agcctgaata aaatgcacca tgaggactcc 8050

 gatgaatcat ccgaggagga ggacctcaca gccagccaga tcctggagca 8100

 ctcagaccta atcatgactc tctccccctc tgaagagacg aatcccatgg 8150

 agctgctcac cacagcctgt gactcgaccc ctgcagaacc tcattccttt 8200

 aacaccagaa tgtccagctt tgatgcttcc ttgcctgata tgaataatct 8250

 gcagatttct gagggttcaa aggctgaagc tgttcgtgag gaggaggaca 8300

 ccaccgtgca tgaggatgat ctttctagtt ccatcaatga actcccagca 8350

 gcttttgaat gcagcgacag ctttagcctg gacatgactg agggggaaga 8400

 aaaaggcaat cgggcactgg accagtttac cctggcgagc tttggagaag 8450

 gtgacagggg agtctctccc cctccctcgc ccttcttctc agccatcctt 8500

 gccgcctttc agcccgcagc ctgtgacgat gccgaggagg cctggcgcag 8550

 ccacatcaac cagcttatgt gtgactcaga tggctcctgt gctgtgtata 8600

 catttcatgt gttctcctcc ttgtttaaga atattcagaa aaggttctgc 8650

 ttcctaacct gtgatgcagc cagttacctt ggagataacc tccggggaat 8700

 cggatccaaa tttgtcagct cttcccagat gctcacctcc tgctctgaat 8750

 gtcctacact ttttgtggat gccgagactc tcctttcatg tggacttctg 8800

 gacaagctca agttcagtgt gttagaactg caagaatatt tggataccta 8850

 caacaacagg aaagaggcca cactctcttg gcttgcaaat tgtaaggcaa 8900

 catttgcagg gggatcaaga gatggagtaa ttacctgtca accaggggac 8950

 tccgaagaaa agcaattgga actgtgtcag agattatata agctacactt 9000

 ccagctgcta ttgctttttc agtcctactg taagctcatc ggccaggtgc 9050

 acgaagttag ctccatgcca gagctgctga atatgtccag ggaactgagt 9100

 gacctaaaga aacacctgaa ggaagccagt gcagtcattg cagctgaccc 9150

 tctctattca gacggcgcgt ggtccgagcc caccttcacg tccactgaag 9200

 cagccatcca gtccatgctg gagtgcctga agaacaacga actcggcaaa 9250

 gctttgcggc agatcaggga gtgcagaagt ctgtggccca atgacatctt 9300

 tggaagcagt tctgatgatg aggtccagac actactgaat atttatttcc 9350

 gtcaccaaac tctgggacag acgggtactt atgccctggt ggggtctaac 9400

 cagagcctga ccgagatctg caccaagctg atggagctga acatggagat 9450

 ccgggacatg atccgcaggg cccagagtta ccgagtcctc actacttttc 9500

 ttccagactc cagtgtttct ggcactagtc tctgacagga gcctcctgtc 9550

 cccactgggt tccaaactgc agtgctgcca tgctggggca acgtcattca 9600

 gtgtcttctc ggccttcaaa aggcttggac agactgttct ccctcttgtt 9650

 acctgtaggg ctttttctaa agaggatggc agaacttcca acgtgtagca 9700

 atactataag aaccaaggta gcttagaacg tcctggacag actccactca 9750

 tcatgctgtg tggcacaaat gtgttacatt tgaccgagca tatgcaactc 9800

 gctactgaag aagtgacttc cgttgcatac caaagccgac tacactgaac 9850

 agtaccttcc tttctagaaa caattttaga ttggcaaaag tgcaatgttt 9900

 tcttcactca aaaaatttta tattctcaaa catgtatatt ctttccctgt 9950

 cttgttccat tttcttttct tttttctttt ttctttttcc tttctttcgt 10000

 gggctgagaa aggggcaggc aaaatgaagc tggccactga aaactgtaag 10050

 atggtcaaaa gctgacagcc tgtgtatgtg aaaagggaat tgtaaatgga 10100

 ctgcaatgta atgtacactg taatttgaat acaattactg tatctaaaag 10150

 gagctgctat gaagtacctt tcttatgttg ctaggctact gtttctgaaa 10200

 gccctggatc tctttgcacc aaaaatggtc cagatagact ctttttaagg 10250

 atcttggctg ctttttacta gaaggttgct tttatgagca tatttatact 10300

 gctgaaggat gagtgttaat tttaattaac tttgccgttt tgtagagaaa 10350

 actattcaca agataaattc caagtctttt cacctgtcag gcatgcatat 10400

 tttaatatct gtttggatag tcagaagtag aatcataaag gtaaaatatg 10450

 agttgttact ttgtttcttc gatgtcatat tttatgtgta atatatatgt 10500

 aaagggccat tcttaagttc tctccttaaa cttaatgctg tcaagtgtta 10550

 gatgtgtgca tgtgaacttg ttgcactgca gaaacatatt cagagtttat 10600

 ctatgtaact tattcactct gtaaatacat ttaaagtttt tgtgatgtaa 10650

 gcttaattga tattctgttc agaactttct ttagactaaa aaaaaaaaaa 10700

 aaagacaaa 10709

<210> 5951
<211> 3012
<212> PRT
<213> Homo sapien

<400> 5951
 Met Ala Ser Gln Gln Asp Ser Gly Phe Phe Glu Ile Ser Ile Lys
   1               5                  10                  15

 Tyr Leu Leu Lys Ser Trp Ser Asn Thr Ser Pro Val Gly Asn Gly
                  20                  25                  30

 Tyr Ile Lys Pro Pro Val Pro Pro Ala Ser Gly Thr His Arg Glu
                  35                  40                  45

 Lys Gly Pro Pro Thr Met Leu Pro Ile Asn Val Asp Pro Asp Ser
                  50                  55                  60

 Lys Pro Gly Glu Tyr Val Leu Lys Ser Leu Phe Val Asn Phe Thr
                  65                  70                  75

 Thr Gln Ala Glu Arg Lys Ile Arg Ile Ile Met Ala Glu Pro Leu
                  80                  85                  90

 Glu Lys Pro Leu Thr Lys Ser Leu Gln Arg Gly Glu Asp Pro Gln
                  95                 100                 105

 Phe Asp Gln Val Ile Ser Ser Met Ser Ser Leu Ser Glu Tyr Cys
                 110                 115                 120

 Leu Pro Ser Ile Leu Arg Thr Leu Phe Asp Trp Tyr Lys Arg Gln
                 125                 130                 135

 Asn Gly Ile Glu Asp Glu Ser His Glu Tyr Arg Pro Arg Thr Ser
                 140                 145                 150

 Asn Lys Ser Lys Ser Asp Glu Gln Gln Arg Asp Tyr Leu Met Glu
                 155                 160                 165

 Arg Arg Asp Leu Ala Ile Asp Phe Ile Phe Ser Leu Val Leu Ile
                 170                 175                 180

 Glu Val Leu Lys Gln Ile Pro Leu His Pro Val Ile Asp Ser Leu
                 185                 190                 195

 Ile His Asp Val Ile Asn Leu Ala Phe Lys His Phe Lys Tyr Lys
                 200                 205                 210

 Glu Gly Tyr Leu Gly Pro Asn Thr Gly Asn Met His Ile Val Ala
                 215                 220                 225

 Asp Leu Tyr Ala Glu Val Ile Gly Val Leu Ala Gln Ala Lys Phe
                 230                 235                 240

 Pro Ala Val Lys Lys Lys Phe Met Ala Glu Leu Lys Glu Leu Arg
                 245                 250                 255

 His Lys Glu Gln Asn Pro Tyr Val Val Gln Ser Ile Ile Ser Leu
                 260                 265                 270

 Ile Met Gly Met Lys Phe Phe Arg Ile Lys Met Tyr Pro Val Glu
                 275                 280                 285

 Asp Phe Glu Ala Ser Leu Gln Phe Met Gln Glu Cys Ala His Tyr
                 290                 295                 300

 Phe Leu Glu Val Lys Asp Lys Asp Ile Lys His Ala Leu Ala Gly
                 305                 310                 315

 Leu Phe Val Glu Ile Leu Val Pro Val Ala Ala Ala Val Lys Asn
                 320                 325                 330

 Glu Val Asn Val Pro Cys Leu Arg Asn Phe Val Glu Ser Leu Tyr
                 335                 340                 345

 Asp Thr Thr Leu Glu Leu Ser Ser Arg Lys Lys His Ser Leu Ala
                 350                 355                 360

 Leu Tyr Pro Leu Val Thr Cys Leu Leu Cys Val Ser Gln Lys Gln
                 365                 370                 375

 Leu Phe Leu Asn Arg Trp His Ile Phe Leu Asn Asn Cys Leu Ser
                 380                 385                 390

 Asn Leu Lys Asn Lys Asp Pro Lys Met Ala Arg Val Ala Leu Glu
                 395                 400                 405

 Ser Leu Tyr Arg Leu Leu Trp Val Tyr Met Ile Arg Ile Lys Cys
                 410                 415                 420

 Glu Ser Asn Thr Ala Thr Gln Ser Arg Leu Ile Thr Ile Ile Thr
                 425                 430                 435

 Thr Leu Phe Pro Lys Gly Ser Arg Gly Val Val Pro Arg Asp Met
                 440                 445                 450

 Pro Leu Asn Ile Phe Val Lys Ile Ile Gln Phe Ile Ala Gln Glu
                 455                 460                 465

 Arg Leu Asp Phe Ala Met Lys Glu Ile Ile Phe Asp Phe Leu Cys
                 470                 475                 480

 Val Gly Lys Pro Ala Lys Ala Phe Ser Leu Asn Pro Glu Arg Met
                 485                 490                 495

 Asn Ile Gly Leu Arg Ala Phe Leu Val Ile Ala Asp Ser Leu Gln
                 500                 505                 510

 Gln Lys Asp Gly Glu Pro Pro Met Pro Val Thr Gly Ala Val Leu
                 515                 520                 525

 Pro Ser Gly Asn Thr Leu Arg Val Lys Lys Thr Tyr Leu Ser Lys
                 530                 535                 540

 Thr Leu Thr Glu Glu Glu Ala Lys Met Ile Gly Met Ser Leu Tyr
                 545                 550                 555

 Tyr Ser Gln Val Arg Lys Ala Val Asp Asn Ile Leu Arg His Leu
                 560                 565                 570

 Asp Lys Glu Val Gly Arg Cys Met Met Leu Thr Asn Val Gln Met
                 575                 580                 585

 Leu Asn Lys Glu Pro Glu Asp Met Ile Thr Gly Glu Arg Lys Pro
                 590                 595                 600

 Lys Ile Asp Leu Phe Arg Thr Cys Val Ala Ala Ile Pro Arg Leu
                 605                 610                 615

 Leu Pro Asp Gly Met Ser Lys Leu Glu Leu Ile Asp Leu Leu Ala
                 620                 625                 630

 Arg Leu Ser Ile His Met Asp Asp Glu Leu Arg His Ile Ala Gln
                 635                 640                 645

 Asn Ser Leu Gln Gly Leu Leu Val Asp Phe Ser Asp Trp Arg Glu
                 650                 655                 660

 Asp Val Leu Phe Gly Phe Thr Asn Phe Leu Leu Arg Glu Val Asn
                 665                 670                 675

 Asp Met His His Thr Leu Leu Asp Ser Ser Leu Lys Leu Leu Leu
                 680                 685                 690

 Gln Leu Leu Thr Gln Trp Lys Leu Val Ile Gln Thr Gln Gly Lys
                 695                 700                 705

 Val Tyr Glu Gln Ala Asn Lys Ile Arg Asn Ser Glu Leu Ile Ala
                 710                 715                 720

 Asn Gly Ser Ser His Arg Ile Gln Ser Glu Arg Gly Pro His Cys
                 725                 730                 735

 Ser Val Leu His Ala Val Glu Gly Phe Ala Leu Val Leu Leu Cys
                 740                 745                 750

 Ser Phe Gln Val Ala Thr Arg Lys Leu Ser Val Leu Ile Leu Lys
                 755                 760                 765

 Glu Ile Arg Ala Leu Phe Ile Ala Leu Gly Gln Pro Glu Asp Asp
                 770                 775                 780

 Asp Arg Pro Met Ile Asp Val Met Asp Gln Leu Ser Ser Ser Ile
                 785                 790                 795

 Leu Glu Ser Phe Ile His Val Ala Val Ser Asp Ser Ala Thr Leu
                 800                 805                 810

 Pro Leu Thr His Asn Val Asp Leu Gln Trp Leu Val Glu Trp Asn
                 815                 820                 825

 Ala Val Leu Val Asn Ser His Tyr Asp Val Lys Ser Pro Ser His
                 830                 835                 840

 Val Trp Ile Phe Ala Gln Ser Val Lys Asp Pro Trp Val Leu Cys
                 845                 850                 855

 Leu Phe Ser Phe Leu Arg Gln Glu Asn Leu Pro Lys His Cys Pro
                 860                 865                 870

 Thr Ala Leu Ser Tyr Ala Trp Pro Tyr Ala Phe Thr Arg Leu Gln
                 875                 880                 885

 Ser Val Met Pro Leu Val Asp Pro Asn Ser Pro Ile Asn Ala Lys
                 890                 895                 900

 Lys Thr Ser Thr Ala Gly Ser Gly Asp Asn Tyr Val Thr Leu Trp
                 905                 910                 915

 Arg Asn Tyr Leu Ile Leu Cys Phe Gly Val Ala Lys Pro Ser Ile
                 920                 925                 930

 Met Ser Pro Gly His Leu Arg Ala Ser Thr Pro Glu Ile Met Ala
                 935                 940                 945

 Thr Thr Pro Asp Gly Thr Val Ser Tyr Asp Asn Lys Ala Ile Gly
                 950                 955                 960

 Thr Pro Ser Val Gly Val Leu Leu Lys Gln Leu Val Pro Leu Met
                 965                 970                 975

 Arg Leu Glu Ser Ile Glu Ile Thr Glu Ser Leu Val Leu Gly Phe
                 980                 985                 990

 Gly Arg Thr Asn Ser Leu Val Phe Arg Glu Leu Val Glu Glu Leu
                 995                1000                1005

 His Pro Leu Met Lys Glu Ala Leu Glu Arg Arg Pro Glu Asn Lys
                1010                1015                1020

 Lys Arg Arg Glu Arg Arg Asp Leu Leu Arg Leu Gln Leu Leu Arg
                1025                1030                1035

 Ile Phe Glu Leu Leu Ala Asp Ala Gly Val Ile Ser Asp Ser Thr
                1040                1045                1050

 Asn Gly Ala Leu Glu Arg Asp Thr Leu Ala Leu Gly Ala Leu Phe
                1055                1060                1065

 Leu Glu Tyr Val Asp Leu Thr Arg Met Leu Leu Glu Ala Glu Asn
                1070                1075                1080

 Asp Lys Glu Val Glu Ile Leu Lys Asp Ile Arg Ala His Phe Ser
                1085                1090                1095

 Ala Met Val Ala Asn Leu Ile Gln Cys Val Pro Val His His Arg
                1100                1105                1110

 Arg Phe Leu Phe Pro Gln Gln Ser Leu Arg His His Leu Phe Ile
                1115                1120                1125

 Leu Phe Ser Gln Trp Ala Gly Pro Phe Ser Ile Met Phe Thr Pro
                1130                1135                1140

 Leu Asp Arg Tyr Ser Asp Arg Asn His Gln Ile Thr Arg Tyr Gln
                1145                1150                1155

 Tyr Cys Ala Leu Lys Ala Met Ser Ala Val Leu Cys Cys Gly Pro
                1160                1165                1170

 Val Phe Asp Asn Val Gly Leu Ser Pro Asp Gly Tyr Leu Tyr Lys
                1175                1180                1185

 Trp Leu Asp Asn Ile Leu Ala Cys Gln Asp Leu Arg Val His Gln
                1190                1195                1200

 Leu Gly Cys Glu Val Val Val Leu Leu Leu Glu Leu Asn Pro Asp
                1205                1210                1215

 Gln Ile Asn Leu Phe Asn Trp Ala Ile Asp Arg Cys Tyr Thr Gly
                1220                1225                1230

 Ser Tyr Gln Leu Ala Ser Gly Cys Phe Lys Ala Ile Ala Thr Val
                1235                1240                1245

 Cys Gly Ser Arg Asn Tyr Pro Phe Asp Ile Val Thr Leu Leu Asn
                1250                1255                1260

 Leu Val Leu Phe Lys Ala Ser Asp Thr Asn Arg Glu Ile Tyr Glu
                1265                1270                1275

 Ile Ser Met Gln Leu Met Gln Ile Leu Glu Ala Lys Leu Phe Val
                1280                1285                1290

 Tyr Ser Lys Lys Val Ala Glu Gln Arg Pro Gly Ser Ile Leu Tyr
                1295                1300                1305

 Gly Thr His Gly Pro Leu Pro Pro Leu Tyr Ser Val Ser Leu Ala
                1310                1315                1320

 Leu Leu Ser Cys Glu Leu Ala Arg Met Tyr Pro Glu Leu Thr Leu
                1325                1330                1335

 Pro Leu Phe Ser Gly Lys Pro Ala Ile Pro His Asn Thr Pro Gln
                1340                1345                1350

 Arg Ala Pro Asp His Ala Tyr Leu Pro Ala Ala Leu Ala Ala Gln
                1355                1360                1365

 His Arg Ala Gly Gly Gln Gln Ala Pro Pro Pro Gly Ser Ser Pro
                1370                1375                1380

 Ser Ser Pro Glu Asp Glu Val Lys Asp Arg Glu Gly Asp Val Thr
                1385                1390                1395

 Ala Ser His Gly Leu Arg Gly Asn Gly Trp Gly Ser Pro Glu Ala
                1400                1405                1410

 Thr Ser Leu Val Leu Asn Asn Leu Met Tyr Met Thr Ala Lys Tyr
                1415                1420                1425

 Gly Asp Glu Val Pro Gly Pro Glu Met Glu Asn Ala Trp Asn Ala
                1430                1435                1440

 Leu Ala Asn Asn Glu Lys Trp Ser Asn Asn Leu Arg Ile Thr Leu
                1445                1450                1455

 Gln Phe Leu Ile Ser Leu Cys Gly Val Ser Ser Asp Thr Val Leu
                1460                1465                1470

 Leu Pro Tyr Ile Lys Lys Val Ala Ile Tyr Leu Cys Arg Asn Asn
                1475                1480                1485

 Thr Ile Gln Thr Met Glu Glu Leu Leu Phe Glu Leu Gln Gln Thr
                1490                1495                1500

 Glu Pro Val Asn Pro Ile Val Gln His Cys Asp Asn Pro Pro Phe
                1505                1510                1515

 Tyr Arg Phe Thr Ala Ser Ser Lys Ala Ser Ala Ala Ala Ser Gly
                1520                1525                1530

 Thr Thr Ser Ser Ser Asn Thr Val Val Ala Gly Gln Glu Asn Phe
                1535                1540                1545

 Pro Asp Ala Glu Glu Asn Lys Ile Leu Lys Glu Ser Asp Glu Arg
                1550                1555                1560

 Phe Ser Asn Val Ile Arg Ala His Thr Arg Leu Glu Ser Arg Tyr
                1565                1570                1575

 Ser Asn Ser Ser Gly Gly Ser Tyr Asp Glu Asp Lys Asn Asp Pro
                1580                1585                1590

 Ile Ser Pro Tyr Thr Gly Trp Leu Leu Thr Ile Thr Glu Thr Lys
                1595                1600                1605

 Gln Pro Gln Pro Leu Pro Met Pro Cys Thr Gly Gly Cys Trp Ala
                1610                1615                1620

 Pro Leu Val Asp Tyr Leu Pro Glu Thr Ile Thr Pro Arg Gly Pro
                1625                1630                1635

 Leu His Arg Cys Asn Ile Ala Val Ile Phe Met Thr Glu Met Val
                1640                1645                1650

 Val Asp His Ser Val Arg Glu Asp Trp Ala Leu His Leu Pro Leu
                1655                1660                1665

 Leu Leu His Ala Val Phe Leu Gly Leu Asp His Tyr Arg Pro Glu
                1670                1675                1680

 Val Phe Glu His Ser Lys Lys Leu Leu Leu His Leu Leu Ile Ala
                1685                1690                1695

 Leu Ser Cys Asn Ser Asn Phe His Ser Ile Ala Ser Val Leu Leu
                1700                1705                1710

 Gln Thr Arg Glu Met Gly Glu Ala Lys Thr Leu Thr Val Gln Pro
                1715                1720                1725

 Ala Tyr Gln Pro Glu Tyr Leu Tyr Thr Gly Gly Phe Asp Phe Leu
                1730                1735                1740

 Arg Glu Asp Gln Ser Ser Pro Val Pro Asp Ser Gly Leu Ser Ser
                1745                1750                1755

 Ser Ser Thr Ser Ser Ser Ile Ser Leu Gly Gly Ser Ser Gly Asn
                1760                1765                1770

 Leu Pro Gln Met Thr Gln Glu Val Glu Asp Val Asp Thr Ala Ala
                1775                1780                1785

 Glu Thr Asp Glu Lys Ala Asn Lys Leu Ile Glu Phe Leu Thr Thr
                1790                1795                1800

 Arg Ala Phe Gly Pro Leu Trp Cys His Glu Asp Ile Thr Pro Lys
                1805                1810                1815

 Asn Gln Asn Ser Lys Ser Ala Glu Gln Leu Thr Asn Phe Leu Arg
                1820                1825                1830

 His Val Val Ser Val Phe Lys Asp Ser Lys Ser Gly Phe His Leu
                1835                1840                1845

 Glu His Gln Leu Ser Glu Val Ala Leu Gln Thr Ala Leu Ala Ser
                1850                1855                1860

 Ser Ser Arg His Tyr Ala Gly Arg Ser Phe Gln Ile Phe Arg Ala
                1865                1870                1875

 Leu Lys Gln Pro Leu Ser Ala His Ala Leu Ser Asp Leu Leu Ser
                1880                1885                1890

 Arg Leu Val Glu Val Ile Gly Glu His Gly Asp Glu Ile Gln Gly
                1895                1900                1905

 Tyr Val Met Glu Ala Leu Leu Thr Leu Glu Ala Ala Val Asp Asn
                1910                1915                1920

 Leu Ser Asp Cys Leu Lys Asn Ser Asp Leu Leu Thr Val Leu Ser
                1925                1930                1935

 Arg Ser Ser Ser Pro Asp Leu Ser Ser Ser Ser Lys Leu Thr Ala
                1940                1945                1950

 Ser Arg Lys Ser Thr Gly Gln Leu Asn Met Asn Pro Gly Thr Thr
                1955                1960                1965

 Ser Gly Asn Thr Ala Thr Ala Glu Arg Ser Arg His Gln Arg Ser
                1970                1975                1980

 Phe Ser Val Pro Lys Lys Phe Gly Val Ile Asp Arg Ser Ser Asp
                1985                1990                1995

 Pro Pro Arg Ser Ala Thr Leu Asp Arg Ile Gln Ala Cys Thr Gln
                2000                2005                2010

 Gln Gly Leu Ser Ser Lys Thr Arg Ser Ser Ser Ser Leu Lys Asp
                2015                2020                2025

 Ser Leu Thr Asp Pro Ser His Ile Asn His Pro Thr Asn Leu Leu
                2030                2035                2040

 Ala Thr Ile Phe Trp Val Thr Val Ala Leu Met Glu Ser Asp Phe
                2045                2050                2055

 Glu Phe Glu Tyr Leu Met Ala Leu Arg Leu Leu Ser Arg Leu Leu
                2060                2065                2070

 Ala His Met Pro Leu Asp Lys Ala Glu Asn Arg Glu Lys Leu Glu
                2075                2080                2085

 Lys Leu Gln Ala Gln Leu Lys Trp Ala Asp Phe Ser Gly Leu Gln
                2090                2095                2100

 Gln Leu Leu Leu Lys Gly Phe Thr Ser Leu Thr Thr Thr Asp Leu
                2105                2110                2115

 Thr Leu Gln Leu Phe Ser Leu Leu Thr Pro Val Ser Lys Ile Ser
                2120                2125                2130

 Met Val Asp Ala Ser His Ala Ile Gly Phe Pro Leu Asn Val Leu
                2135                2140                2145

 Cys Leu Leu Pro Gln Leu Ile Gln His Phe Glu Asn Pro Asn Gln
                2150                2155                2160

 Phe Cys Lys Asp Ile Ala Glu Arg Ile Ala Gln Val Cys Leu Glu
                2165                2170                2175

 Glu Lys Asn Pro Lys Leu Ser Asn Leu Ala His Val Met Thr Leu
                2180                2185                2190

 Tyr Lys Thr His Ser Tyr Thr Arg Asp Cys Ala Thr Trp Val Asn
                2195                2200                2205

 Val Val Cys Arg Tyr Leu His Glu Ala Tyr Ala Asp Ile Thr Leu
                2210                2215                2220

 Asn Met Val Thr Tyr Leu Ala Glu Leu Leu Glu Lys Gly Leu Pro
                2225                2230                2235

 Ser Val Gln Gln Pro Leu Leu Gln Val Ile Tyr Ser Leu Leu Ser
                2240                2245                2250

 Tyr Met Asp Leu Ser Val Val Pro Val Lys Gln Phe Asn Val Glu
                2255                2260                2265

 Val Leu Lys Thr Ile Glu Lys Tyr Val Gln Ser Val His Trp Arg
                2270                2275                2280

 Glu Ala Leu Asn Ile Leu Lys Leu Val Val Ser Arg Ser Ala Ser
                2285                2290                2295

 Leu Val Leu Pro Ser Tyr Gln His Ser Asp Leu Ser Lys Ile Glu
                2300                2305                2310

 Ile His Arg Val Trp Thr Ser Ala Ser Lys Glu Leu Pro Gly Lys
                2315                2320                2325

 Thr Leu Asp Phe His Phe Asp Ile Ser Glu Thr Pro Ile Ile Gly
                2330                2335                2340

 Arg Arg Tyr Asp Glu Leu Gln Asn Ser Ser Gly Arg Asp Gly Lys
                2345                2350                2355

 Pro Arg Ala Met Ala Val Thr Arg Ser Thr Ser Ser Thr Ser Ser
                2360                2365                2370

 Gly Ser Asn Ser Asn Val Leu Val Pro Val Ser Trp Lys Arg Pro
                2375                2380                2385

 Gln Tyr Ser Gln Lys Arg Thr Lys Glu Lys Leu Val His Val Leu
                2390                2395                2400

 Ser Leu Cys Gly Gln Glu Val Gly Leu Ser Lys Asn Pro Ser Val
                2405                2410                2415

 Ile Phe Ser Ser Cys Gly Asp Leu Asp Leu Leu Glu His Gln Thr
                2420                2425                2430

 Ser Leu Val Ser Ser Glu Asp Gly Ala Arg Glu Gln Glu Asn Met
                2435                2440                2445

 Asp Asp Thr Asn Ser Glu Gln Gln Phe Arg Val Phe Arg Asp Phe
                2450                2455                2460

 Asp Phe Leu Asp Val Glu Leu Glu Asp Gly Glu Gly Glu Ser Met
                2465                2470                2475

 Asp Asn Phe Asn Trp Gly Val Arg Arg Arg Ser Leu Asp Ser Leu
                2480                2485                2490

 Asp Lys Cys Asp Met Gln Ile Leu Glu Glu Arg Gln Leu Ser Gly
                2495                2500                2505

 Ser Thr Pro Ser Leu Asn Lys Met His His Glu Asp Ser Asp Glu
                2510                2515                2520

 Ser Ser Glu Glu Glu Asp Leu Thr Ala Ser Gln Ile Leu Glu His
                2525                2530                2535

 Ser Asp Leu Ile Met Thr Leu Ser Pro Ser Glu Glu Thr Asn Pro
                2540                2545                2550

 Met Glu Leu Leu Thr Thr Ala Cys Asp Ser Thr Pro Ala Glu Pro
                2555                2560                2565

 His Ser Phe Asn Thr Arg Met Ser Ser Phe Asp Ala Ser Leu Pro
                2570                2575                2580

 Asp Met Asn Asn Leu Gln Ile Ser Glu Gly Ser Lys Ala Glu Ala
                2585                2590                2595

 Val Arg Glu Glu Glu Asp Thr Thr Val His Glu Asp Asp Leu Ser
                2600                2605                2610

 Ser Ser Ile Asn Glu Leu Pro Ala Ala Phe Glu Cys Ser Asp Ser
                2615                2620                2625

 Phe Ser Leu Asp Met Thr Glu Gly Glu Glu Lys Gly Asn Arg Ala
                2630                2635                2640

 Leu Asp Gln Phe Thr Leu Ala Ser Phe Gly Glu Gly Asp Arg Gly
                2645                2650                2655

 Val Ser Pro Pro Pro Ser Pro Phe Phe Ser Ala Ile Leu Ala Ala
                2660                2665                2670

 Phe Gln Pro Ala Ala Cys Asp Asp Ala Glu Glu Ala Trp Arg Ser
                2675                2680                2685

 His Ile Asn Gln Leu Met Cys Asp Ser Asp Gly Ser Cys Ala Val
                2690                2695                2700

 Tyr Thr Phe His Val Phe Ser Ser Leu Phe Lys Asn Ile Gln Lys
                2705                2710                2715

 Arg Phe Cys Phe Leu Thr Cys Asp Ala Ala Ser Tyr Leu Gly Asp
                2720                2725                2730

 Asn Leu Arg Gly Ile Gly Ser Lys Phe Val Ser Ser Ser Gln Met
                2735                2740                2745

 Leu Thr Ser Cys Ser Glu Cys Pro Thr Leu Phe Val Asp Ala Glu
                2750                2755                2760

 Thr Leu Leu Ser Cys Gly Leu Leu Asp Lys Leu Lys Phe Ser Val
                2765                2770                2775

 Leu Glu Leu Gln Glu Tyr Leu Asp Thr Tyr Asn Asn Arg Lys Glu
                2780                2785                2790

 Ala Thr Leu Ser Trp Leu Ala Asn Cys Lys Ala Thr Phe Ala Gly
                2795                2800                2805

 Gly Ser Arg Asp Gly Val Ile Thr Cys Gln Pro Gly Asp Ser Glu
                2810                2815                2820

 Glu Lys Gln Leu Glu Leu Cys Gln Arg Leu Tyr Lys Leu His Phe
                2825                2830                2835

 Gln Leu Leu Leu Leu Phe Gln Ser Tyr Cys Lys Leu Ile Gly Gln
                2840                2845                2850

 Val His Glu Val Ser Ser Met Pro Glu Leu Leu Asn Met Ser Arg
                2855                2860                2865

 Glu Leu Ser Asp Leu Lys Lys His Leu Lys Glu Ala Ser Ala Val
                2870                2875                2880

 Ile Ala Ala Asp Pro Leu Tyr Ser Asp Gly Ala Trp Ser Glu Pro
                2885                2890                2895

 Thr Phe Thr Ser Thr Glu Ala Ala Ile Gln Ser Met Leu Glu Cys
                2900                2905                2910

 Leu Lys Asn Asn Glu Leu Gly Lys Ala Leu Arg Gln Ile Arg Glu
                2915                2920                2925

 Cys Arg Ser Leu Trp Pro Asn Asp Ile Phe Gly Ser Ser Ser Asp
                2930                2935                2940

 Asp Glu Val Gln Thr Leu Leu Asn Ile Tyr Phe Arg His Gln Thr
                2945                2950                2955

 Leu Gly Gln Thr Gly Thr Tyr Ala Leu Val Gly Ser Asn Gln Ser
                2960                2965                2970

 Leu Thr Glu Ile Cys Thr Lys Leu Met Glu Leu Asn Met Glu Ile
                2975                2980                2985

 Arg Asp Met Ile Arg Arg Ala Gln Ser Tyr Arg Val Leu Thr Thr
                2990                2995                3000

 Phe Leu Pro Asp Ser Ser Val Ser Gly Thr Ser Leu
                3005                3010

<210> 5952
<211> 5287
<212> DNA
<213> Homo sapien

<400> 5952
 ctggccgcgg cgtggggaca gcgaggcgca ctggggcctc ccagcgccgg 50

 gccggccgcg ccgtccagcc cgaggtctac ggctttgcgc tccgagccca 100

 gaggaagatg cctgccggca ccgagctcgg gctgcggggc tgaacgcctg 150

 tcttccaggc gcacggcagc actgccctcg gccggtgtcg gtagcggcac 200

 tcggcgtgcc ccgggcggac gaagagcgca ggctgggtac accttgcccg 250

 aatcggcgga gttcgcagct agcgagggcg ggccggccgg cccggatggg 300

 cgcggggttt gcggcccccg ccgggtgctc cggagcggcc cgggcaccgg 350

 gggcacgctg agtgccggag ccgcggccgc agagagaact tggggcgggg 400

 gccatgcacc ggtgcggagt ctagagccga gcggagcgcc ccgcgggccc 450

 gcccgcgtct gcggccgttc gggtcctcac agtccccgcg cccggagttc 500

 gcagcgcgct ccagacaaga tggcgcggcc ggtccgggga gggctcgggg 550

 ccccgcgccg ctcgccttgc cttctccttc tctggctgct tttgcttcgg 600

 ctggagccgg tgaccgccgc ggccggcccg cgggcgccct gcgcggccgc 650

 ctgcacttgc gctggggact cgctggactg cggtgggcgc gggctggctg 700

 cgttgcccgg ggacctgccc tcctggacgc ggagcctaaa cctgagttac 750

 aacaaactct ctgagattga ccctgctggt tttgaggact tgccgaacct 800

 acaggaagtg tacctcaata ataatgagtt gacagcggta ccatccctgg 850

 gcgctgcttc atcacatgtc gtctctctct ttctgcagca caacaagatt 900

 cgcagcgtgg aggggagcca gctgaaggcc tacctttcct tagaagtgtt 950

 agatctgagt ttgaacaaca tcacggaagt gcggaacacc tgctttccac 1000

 acggaccgcc tataaaggag ctcaacctgg caggcaatcg gattggcacc 1050

 ctggagttgg gagcatttga tggtctgtca cggtcgctgc taactcttcg 1100

 cctgagcaaa aacaggatca cccagcttcc tgtaagagca ttcaagctac 1150

 ccaggctgac acaactggac ctcaatcgga acaggattcg gctgatagag 1200

 ggcctcacct tccaggggct caacagcttg gaggtgctga agcttcagcg 1250

 aaacaacatc agcaaactga cagatggggc cttctgggga ctgtccaaga 1300

 tgcatgtgct gcacctggag tacaacagcc tggtagaagt gaacagcggc 1350

 tcgctctacg gcctcacggc cctgcatcag ctccacctca gcaacaattc 1400

 catcgctcgc attcaccgca agggctggag cttctgccag aagctgcatg 1450

 agttggtcct gtccttcaac aacctgacac ggctggacga ggagagcctg 1500

 gccgagctga gcagcctgag tgtcctgcgt ctcagccaca attccatcag 1550

 ccacattgcg gagggtgcct tcaagggact caggagcctg cgagtcttgg 1600

 atctggacca taacgagatt tcgggcacaa tagaggacac gagcggcgcc 1650

 ttctcagggc tcgacagcct cagcaagctg actctgtttg gaaacaagat 1700

 caagtctgtg gctaagagag cattctcggg gctggaaggc ctggagcacc 1750

 tgaaccttgg agggaatgcg atcagatctg tccagtttga tgcctttgtg 1800

 aagatgaaga atcttaaaga gctccatatc agcagcgaca gcttcctgtg 1850

 tgactgccag ctgaagtggc tgcccccgtg gctaattggc aggatgctgc 1900

 aggcctttgt gacagccacc tgtgcccacc cagaatcact gaagggtcag 1950

 agcattttct ctgtgccacc agagagtttc gtgtgcgatg acttcctgaa 2000

 gccacagatc atcacccagc cagaaaccac catggctatg gtgggcaagg 2050

 acatccggtt tacatgctca gcagccagca gcagcagctc ccccatgacc 2100

 tttgcctgga agaaagacaa tgaagtcctg accaatgcag acatggagaa 2150

 ctttgtccac gtccacgcgc aggacgggga agtgatggag tacaccacca 2200

 tcctgcacct ccgtcaggtc actttcgggc acgagggccg ctaccaatgt 2250

 gtcatcacca accactttgg ctccacctat tcacataagg ccaggctcac 2300

 tgtgaatgtg ttgccatcat tcaccaaaac gccccacgac ataaccatcc 2350

 ggaccaccac catggcccgc ctcgaatgtg ctgccacagg tcacccaaac 2400

 cctcagattg cctggcagaa ggatggaggc acggatttcc ccgctgcccg 2450

 tgagcgacgc atgcatgtca tgccggatga cgacgtgttt ttcatcactg 2500

 atgtgaaaat agatgacgca ggggtttaca gctgtactgc tcagaactca 2550

 gccggttcta tttcagctaa tgccaccctg actgtcctag agaccccatc 2600

 cttggtggtc cccttggaag accgtgtggt atctgtggga gaaacagtgg 2650

 ccctccaatg caaagccacg gggaaccctc cgccccgcat cacctggttc 2700

 aagggggacc gcccgctgag cctcactgag cggcaccacc tgacccctga 2750

 caaccagctc ctggtggttc agaacgtggt ggcagaggat gcgggccgat 2800

 atacctgtga gatgtccaac accctgggca cggagcgagc tcacagccag 2850

 ctgagcgtcc tgcccgcagc aggctgcagg aaggatggga ccacggtagg 2900

 catcttcacc attgctgtcg tgagcagcat cgtcctgacg tcactggtct 2950

 gggtgtgcat catctaccag accaggaaga agagtgaaga gtacagtgtc 3000

 accaacacag atgaaaccgt cgtgccacca gatgttccaa gctacctctc 3050

 ttctcagggg accctttctg accgacaaga aaccgtggtc aggaccgagg 3100

 gtgcgggccc tcaggccaat gggcacattg agagcaatgg tgtgtgtcca 3150

 agagatgcaa gccactttcc agagcccgac actcacagcg ttgcctgcag 3200

 gcagccaaag ctctgtgctg ggtctgcgta tcacaaagag ccgtggaaag 3250

 cgattgagaa agctgaaggg acacctgggc cacataagat ggaacacggt 3300

 ggccgggtcg tatgcagtga ctgcaacacc gaagtggact gttactccag 3350

 gggacaagcc ttccaccccc agcctgtgtc cagagacagc gcacagccaa 3400

 gtgcgccaaa tggcccggag ccgggtggga gtgaccaaga gcattctcca 3450

 catcaccagt gcagcaggac tgccgctggg tcctgccccg agtgccaagg 3500

 gtcgctctac cccagtaacc acgatagaat gctgacggct gtgaagaaaa 3550

 agccaatggc atctctagat gggaaagggg attcttcctg gactttagca 3600

 aggttgtatc acccggactc tacagagcta cagcctgcat cttcattaac 3650

 ttcaggcagt ccagagcgcg cggaagccca gtacttgctt gtttccaatg 3700

 gccacctccc caaagcatgt gacgccagtc ccgagtccac gccactgaca 3750

 ggacagctcc ccgggaaaca gagggtgcca ctgctgttgg caccaaaaag 3800

 ctaggttttg tctacctcag ttcttgtcat accaatctct acgggaaaga 3850

 gaggtaggag aggctgcgag gaagcttggg ttcaagcgtc actcatctgt 3900

 acatagttgt aactcccatg tggagtatca gtcgctcaca ggacttggat 3950

 ctgaagcaca gtaaacgcaa gaggggattt gtgtacaaaa ggcaaaaaaa 4000

 gtatttgata tcattgtaca taagagtttt cagagatttc atatatatct 4050

 tttacagagg ctattttaat ctttagtgca tggttaacag aaaaaaatta 4100

 tacaattttg acaatattat ttttcgtatc aggttgctgt ttaattttgg 4150

 agggggtggg gaaatagttc tggtgcctta acgcatggct ggaatttata 4200

 gaggctacaa ccacatttgt tcacaggagt ttttggtgcg ggtggggaag 4250

 gatggaaggc cttggattta tattgcactt catagacccc taggctgctg 4300

 tgcggtggga ctccacatgc gccggaagga gcttcaggtg agcactgctc 4350

 atgtgtggat gcccctgcaa caggcttccc tgtctgtaga gccaggggtg 4400

 caagtgccat ccacacttgc agtgaatggc ttttcctttt aggtttaagt 4450

 cctgtctgtc tgtaaggcgt agaatctgtc cgtctgtaag gcgtagaatg 4500

 agggttgtta atccatcaca agcaaaaggt cagaacagtt aaacactgcc 4550

 tttcctcctc ctcttatttt atgataaaag caaatgtggc cttctcagta 4600

 tcattcgatt gctatttgag acttttaaat taaggtaaag gctgctggtg 4650

 ttggtacctg tggatttttc tatactgatg ttttcgtttt gccaatataa 4700

 tgagtattac attggccttg ggggacagaa aggaggaagt tctgactttt 4750

 cagggctacc ttatttctac taaggaccca gagcaggcct gtccatgcca 4800

 ttccttcgca cagatgaaac tgagctggga ctggaaagga cagcccttga 4850

 cctgggttct gggtataatt tgcacttttg agactggtag ctaaccatct 4900

 tatgagtgcc aatgtgtcat ttagtaaaac ttaaatagaa acaaggtcct 4950

 tcaaatgttc ctttggccaa aagctgaagg gagttactga gaaaatagtt 5000

 aacaattact gtcaggtgtc atcactgttc aaaaggtaag cacatttaga 5050

 attttgttct tgacagttaa ctgactaatc ttacttccac aaaatatgtg 5100

 aatttgctgc ttctgagagg caatgtgaaa gagggagtat tacttttatg 5150

 tacaaagtta tttatttata gaaattttgg tacagtgtac attgaaaacc 5200

 atgtaaaata ttgaagtgtc taacaaatgg cattgaagtg tctttaataa 5250

 aggttcattt ataaatgtca aaaaaaaaaa aaaaaaa 5287

<210> 5953
<211> 1094
<212> PRT
<213> Homo sapien

<400> 5953
 Met Ala Arg Pro Val Arg Gly Gly Leu Gly Ala Pro Arg Arg Ser
   1               5                  10                  15

 Pro Cys Leu Leu Leu Leu Trp Leu Leu Leu Leu Arg Leu Glu Pro
                  20                  25                  30

 Val Thr Ala Ala Ala Gly Pro Arg Ala Pro Cys Ala Ala Ala Cys
                  35                  40                  45

 Thr Cys Ala Gly Asp Ser Leu Asp Cys Gly Gly Arg Gly Leu Ala
                  50                  55                  60

 Ala Leu Pro Gly Asp Leu Pro Ser Trp Thr Arg Ser Leu Asn Leu
                  65                  70                  75

 Ser Tyr Asn Lys Leu Ser Glu Ile Asp Pro Ala Gly Phe Glu Asp
                  80                  85                  90

 Leu Pro Asn Leu Gln Glu Val Tyr Leu Asn Asn Asn Glu Leu Thr
                  95                 100                 105

 Ala Val Pro Ser Leu Gly Ala Ala Ser Ser His Val Val Ser Leu
                 110                 115                 120

 Phe Leu Gln His Asn Lys Ile Arg Ser Val Glu Gly Ser Gln Leu
                 125                 130                 135

 Lys Ala Tyr Leu Ser Leu Glu Val Leu Asp Leu Ser Leu Asn Asn
                 140                 145                 150

 Ile Thr Glu Val Arg Asn Thr Cys Phe Pro His Gly Pro Pro Ile
                 155                 160                 165

 Lys Glu Leu Asn Leu Ala Gly Asn Arg Ile Gly Thr Leu Glu Leu
                 170                 175                 180

 Gly Ala Phe Asp Gly Leu Ser Arg Ser Leu Leu Thr Leu Arg Leu
                 185                 190                 195

 Ser Lys Asn Arg Ile Thr Gln Leu Pro Val Arg Ala Phe Lys Leu
                 200                 205                 210

 Pro Arg Leu Thr Gln Leu Asp Leu Asn Arg Asn Arg Ile Arg Leu
                 215                 220                 225

 Ile Glu Gly Leu Thr Phe Gln Gly Leu Asn Ser Leu Glu Val Leu
                 230                 235                 240

 Lys Leu Gln Arg Asn Asn Ile Ser Lys Leu Thr Asp Gly Ala Phe
                 245                 250                 255

 Trp Gly Leu Ser Lys Met His Val Leu His Leu Glu Tyr Asn Ser
                 260                 265                 270

 Leu Val Glu Val Asn Ser Gly Ser Leu Tyr Gly Leu Thr Ala Leu
                 275                 280                 285

 His Gln Leu His Leu Ser Asn Asn Ser Ile Ala Arg Ile His Arg
                 290                 295                 300

 Lys Gly Trp Ser Phe Cys Gln Lys Leu His Glu Leu Val Leu Ser
                 305                 310                 315

 Phe Asn Asn Leu Thr Arg Leu Asp Glu Glu Ser Leu Ala Glu Leu
                 320                 325                 330

 Ser Ser Leu Ser Val Leu Arg Leu Ser His Asn Ser Ile Ser His
                 335                 340                 345

 Ile Ala Glu Gly Ala Phe Lys Gly Leu Arg Ser Leu Arg Val Leu
                 350                 355                 360

 Asp Leu Asp His Asn Glu Ile Ser Gly Thr Ile Glu Asp Thr Ser
                 365                 370                 375

 Gly Ala Phe Ser Gly Leu Asp Ser Leu Ser Lys Leu Thr Leu Phe
                 380                 385                 390

 Gly Asn Lys Ile Lys Ser Val Ala Lys Arg Ala Phe Ser Gly Leu
                 395                 400                 405

 Glu Gly Leu Glu His Leu Asn Leu Gly Gly Asn Ala Ile Arg Ser
                 410                 415                 420

 Val Gln Phe Asp Ala Phe Val Lys Met Lys Asn Leu Lys Glu Leu
                 425                 430                 435

 His Ile Ser Ser Asp Ser Phe Leu Cys Asp Cys Gln Leu Lys Trp
                 440                 445                 450

 Leu Pro Pro Trp Leu Ile Gly Arg Met Leu Gln Ala Phe Val Thr
                 455                 460                 465

 Ala Thr Cys Ala His Pro Glu Ser Leu Lys Gly Gln Ser Ile Phe
                 470                 475                 480

 Ser Val Pro Pro Glu Ser Phe Val Cys Asp Asp Phe Leu Lys Pro
                 485                 490                 495

 Gln Ile Ile Thr Gln Pro Glu Thr Thr Met Ala Met Val Gly Lys
                 500                 505                 510

 Asp Ile Arg Phe Thr Cys Ser Ala Ala Ser Ser Ser Ser Ser Pro
                 515                 520                 525

 Met Thr Phe Ala Trp Lys Lys Asp Asn Glu Val Leu Thr Asn Ala
                 530                 535                 540

 Asp Met Glu Asn Phe Val His Val His Ala Gln Asp Gly Glu Val
                 545                 550                 555

 Met Glu Tyr Thr Thr Ile Leu His Leu Arg Gln Val Thr Phe Gly
                 560                 565                 570

 His Glu Gly Arg Tyr Gln Cys Val Ile Thr Asn His Phe Gly Ser
                 575                 580                 585

 Thr Tyr Ser His Lys Ala Arg Leu Thr Val Asn Val Leu Pro Ser
                 590                 595                 600

 Phe Thr Lys Thr Pro His Asp Ile Thr Ile Arg Thr Thr Thr Met
                 605                 610                 615

 Ala Arg Leu Glu Cys Ala Ala Thr Gly His Pro Asn Pro Gln Ile
                 620                 625                 630

 Ala Trp Gln Lys Asp Gly Gly Thr Asp Phe Pro Ala Ala Arg Glu
                 635                 640                 645

 Arg Arg Met His Val Met Pro Asp Asp Asp Val Phe Phe Ile Thr
                 650                 655                 660

 Asp Val Lys Ile Asp Asp Ala Gly Val Tyr Ser Cys Thr Ala Gln
                 665                 670                 675

 Asn Ser Ala Gly Ser Ile Ser Ala Asn Ala Thr Leu Thr Val Leu
                 680                 685                 690

 Glu Thr Pro Ser Leu Val Val Pro Leu Glu Asp Arg Val Val Ser
                 695                 700                 705

 Val Gly Glu Thr Val Ala Leu Gln Cys Lys Ala Thr Gly Asn Pro
                 710                 715                 720

 Pro Pro Arg Ile Thr Trp Phe Lys Gly Asp Arg Pro Leu Ser Leu
                 725                 730                 735

 Thr Glu Arg His His Leu Thr Pro Asp Asn Gln Leu Leu Val Val
                 740                 745                 750

 Gln Asn Val Val Ala Glu Asp Ala Gly Arg Tyr Thr Cys Glu Met
                 755                 760                 765

 Ser Asn Thr Leu Gly Thr Glu Arg Ala His Ser Gln Leu Ser Val
                 770                 775                 780

 Leu Pro Ala Ala Gly Cys Arg Lys Asp Gly Thr Thr Val Gly Ile
                 785                 790                 795

 Phe Thr Ile Ala Val Val Ser Ser Ile Val Leu Thr Ser Leu Val
                 800                 805                 810

 Trp Val Cys Ile Ile Tyr Gln Thr Arg Lys Lys Ser Glu Glu Tyr
                 815                 820                 825

 Ser Val Thr Asn Thr Asp Glu Thr Val Val Pro Pro Asp Val Pro
                 830                 835                 840

 Ser Tyr Leu Ser Ser Gln Gly Thr Leu Ser Asp Arg Gln Glu Thr
                 845                 850                 855

 Val Val Arg Thr Glu Gly Ala Gly Pro Gln Ala Asn Gly His Ile
                 860                 865                 870

 Glu Ser Asn Gly Val Cys Pro Arg Asp Ala Ser His Phe Pro Glu
                 875                 880                 885

 Pro Asp Thr His Ser Val Ala Cys Arg Gln Pro Lys Leu Cys Ala
                 890                 895                 900

 Gly Ser Ala Tyr His Lys Glu Pro Trp Lys Ala Ile Glu Lys Ala
                 905                 910                 915

 Glu Gly Thr Pro Gly Pro His Lys Met Glu His Gly Gly Arg Val
                 920                 925                 930

 Val Cys Ser Asp Cys Asn Thr Glu Val Asp Cys Tyr Ser Arg Gly
                 935                 940                 945

 Gln Ala Phe His Pro Gln Pro Val Ser Arg Asp Ser Ala Gln Pro
                 950                 955                 960

 Ser Ala Pro Asn Gly Pro Glu Pro Gly Gly Ser Asp Gln Glu His
                 965                 970                 975

 Ser Pro His His Gln Cys Ser Arg Thr Ala Ala Gly Ser Cys Pro
                 980                 985                 990

 Glu Cys Gln Gly Ser Leu Tyr Pro Ser Asn His Asp Arg Met Leu
                 995                1000                1005

 Thr Ala Val Lys Lys Lys Pro Met Ala Ser Leu Asp Gly Lys Gly
                1010                1015                1020

 Asp Ser Ser Trp Thr Leu Ala Arg Leu Tyr His Pro Asp Ser Thr
                1025                1030                1035

 Glu Leu Gln Pro Ala Ser Ser Leu Thr Ser Gly Ser Pro Glu Arg
                1040                1045                1050

 Ala Glu Ala Gln Tyr Leu Leu Val Ser Asn Gly His Leu Pro Lys
                1055                1060                1065

 Ala Cys Asp Ala Ser Pro Glu Ser Thr Pro Leu Thr Gly Gln Leu
                1070                1075                1080

 Pro Gly Lys Gln Arg Val Pro Leu Leu Leu Ala Pro Lys Ser
                1085                1090

<210> 5954
<211> 6509
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3682, 3696, 3699-3700
<223> Unknown base

<400> 5954
 ggcgaggcga ggtttgctgg ggtgaggcag cggcgcggcc gggccgggcc 50

 gggccacagg cggtggcggc gggaccatgg aggcggcggt cgctgctccg 100

 cgtccccggc tgctcctcct cgtgctggcg gcggcggcgg cggcggcggc 150

 ggcgctgctc ccgggggcga cggcgttaca gtgtttctgc cacctctgta 200

 caaaagacaa ttttacttgt gtgacagatg ggctctgctt tgtctctgtc 250

 acagagacca cagacaaagt tatacacaac agcatgtgta tagctgaaat 300

 tgacttaatt cctcgagata ggccgtttgt atgtgcaccc tcttcaaaaa 350

 ctgggtctgt gactacaaca tattgctgca atcaggacca ttgcaataaa 400

 atagaacttc caactactgt aaagtcatca cctggccttg gtcctgtgga 450

 actggcagct gtcattgctg gaccagtgtg cttcgtctgc atctcactca 500

 tgttgatggt ctatatctgc cacaaccgca ctgtcattca ccatcgagtg 550

 ccaaatgaag aggacccttc attagatcgc ccttttattt cagagggtac 600

 tacgttgaaa gacttaattt atgatatgac aacgtcaggt tctggctcag 650

 gtttaccatt gcttgttcag agaacaattg cgagaactat tgtgttacaa 700

 gaaagcattg gcaaaggtcg atttggagaa gtttggagag gaaagtggcg 750

 gggagaagaa gttgctgtta agatattctc ctctagagaa gaacgttcgt 800

 ggttccgtga ggcagagatt tatcaaactg taatgttacg tcatgaaaac 850

 atcctgggat ttatagcagc agacaataaa gacaatggta cttggactca 900

 gctctggttg gtgtcagatt atcatgagca tggatccctt tttgattact 950

 taaacagata cacagttact gtggaaggaa tgataaaact tgctctgtcc 1000

 acggcgagcg gtcttgccca tcttcacatg gagattgttg gtacccaagg 1050

 aaagccagcc attgctcata gagatttgaa atcaaagaat atcttggtaa 1100

 agaagaatgg aacttgctgt attgcagact taggactggc agtaagacat 1150

 gattcagcca cagataccat tgatattgct ccaaaccaca gagtgggaac 1200

 aaaaaggtac atggcccctg aagttctcga tgattccata aatatgaaac 1250

 attttgaatc cttcaaacgt gctgacatct atgcaatggg cttagtattc 1300

 tgggaaattg ctcgacgatg ttccattggt ggaattcatg aagattacca 1350

 actgccttat tatgatcttg taccttctga cccatcagtt gaagaaatga 1400

 gaaaagttgt ttgtgaacag aagttaaggc caaatatccc aaacagatgg 1450

 cagagctgtg aagccttgag agtaatggct aaaattatga gagaatgttg 1500

 gtatgccaat ggagcagcta ggcttacagc attgcggatt aagaaaacat 1550

 tatcgcaact cagtcaacag gaaggcatca aaatgtaatt ctacagcttt 1600

 gcctgaactc tccttttttc ttcagatctg ctcctgggtt ttaatttggg 1650

 aggtcaattg ttctacctca ctgagaggga acagaaggat attgcttcct 1700

 tttgcagcag tgtaataaag tcaattaaaa acttcccagg atttctttgg 1750

 acccaggaaa cagccatgtg ggtcctttct gtgcactatg aacgcttctt 1800

 tcccaggaca gaaaatgtgt agtctacctt tattttttat taacaaaact 1850

 tgttttttaa aaagatgatt gctggtctta actttaggta actctgctgt 1900

 gctggagatc atctttaagg gcaaaggagt tggattgctg aattacaatg 1950

 aaacatgtct tattactaaa gaaagtgatt tactcctggt tagtacattc 2000

 tcagaggatt ctgaaccact agagtttcct tgattcagac tttgaatgta 2050

 ctgttctata gtttttcagg atcttaaaac taacacttat aaaactctta 2100

 tcttgagtct aaaaatgacc tcatatagta gtgaggaaca taattcatgc 2150

 aattgtattt tgtatactat tattgttctt tcacttattc agaacattac 2200

 atgccttcaa aatgggattg tactatacca gtaagtgcca cttctgtgtc 2250

 tttctaatgg aaatgagtag aattgctgaa agtctctatg ttaaaaccta 2300

 tagtgtttga attcaaaaag cttatttatc tgggtaaccc aaactttttc 2350

 tgtttgtttt tggaagggtt ttgtggtatg tcatttggta ttctattctg 2400

 aaaatgcctt tctcctacca aaatgtgctt aagccactaa agaaatgaag 2450

 tggcattaat tagtaaatta ttagcatggt catgtttgaa tattctcaca 2500

 tcaagctttt gcattttaat tgtgttgtct aagtatactt ttaaaaaatc 2550

 aagtggcact ctagatgctt atagtacttt aatatttgta gcatacagac 2600

 taatttttct aaaagggaaa gtctgtctag ctgcttgtga aaagttatgt 2650

 ggtattctgt aagccatttt tttctttatc tgttcaaaga cttatttttt 2700

 aagacatgaa ttacatttaa aattagaata tggttaatat taaataatag 2750

 gcctttttct aggaaggcga aggtagttaa taatttgaat agataacaga 2800

 tgtgcaagaa agtcacattt gttatgtatg taggagtaaa cgttcggtgg 2850

 atcctctgtc tttgtaactg aggttagagc tagtgtggtt ttgaggtctc 2900

 actacacttt gaggaaggca gcttttaatt cagtgtttcc ttatgtgtgc 2950

 gtacattgca actgcttaca tgtaatttat gtaatgcatt cagtgcaccc 3000

 ttgttacttg ggagaggtgg tagctaaaga acattctgag tataggtttt 3050

 tctccattta cagatgtctt tggtcaaata ttgaaagcaa acttgtcatg 3100

 gtcttcttac attaagttga aactagctta taataactgg tttttacttc 3150

 caatgctatg aagtctctgc agggctttta cagttttcga agtcctttta 3200

 tcactgtgat cttattctga ggggagaaaa aactatcata gctctgaggc 3250

 aagacttcga ctttatagtg ctatcagttc cccgatacag ggtcagagta 3300

 acccatacag tattttggtc aggaagagaa agtggccatt tacactgaat 3350

 gagttgcatt ctgataatgt cttatctctt atacgtagaa taaatttgaa 3400

 agactatttg atcttaaaac caaagtaatt ttagaatgag tgacatatta 3450

 cataggaatt tagtgtcaat ttcatgtgtt taaaaacatc atgggaaaaa 3500

 tgcttagagg ttactatttt gactacaaag ttgagttttt ttctgtagtt 3550

 accataattt cattgaagca aatgaatgag tttgagaggt ttgtttttat 3600

 agttgtgttg tattacttgt ttaataataa tctctaattc tgtgatcagg 3650

 tacttttttt gtgggggttt tttttttgtt tntttttcgt cgttgntgnn 3700

 tttgggccat ttctaagcct accagatctg ctttatgaaa tccaggggac 3750

 caatgcattt tatcactaaa actattttta tataatttta agaatatacc 3800

 aaaagttgtc tgatttaaag ttgtaataca tgatttctca ctttcatgta 3850

 aggttatcca cttttgctga agatattttt tattgaatca aagattgagt 3900

 tacaattata cttttcttac ctaagtggat aaaatgtact tttgatgaat 3950

 cagggaattt ttttaaagtt ggagtttagt tctaaattga ctttacgtat 4000

 tactgcagtt aattcctttt ttggctaggg atggtttgat aaaccacaat 4050

 tggctgatat tgaaaatgaa agaaacttaa aaggtgggat ggatcatgat 4100

 tactgtcgat aactgcagat aaatttgatt agagtaataa ttttgtcatt 4150

 taaaaacaca gttgtttata ctgcccatcc taggatgctc accttccaag 4200

 attcaacgtg gctaaaacat cttctggtaa attgtgcgtc catattcatt 4250

 ttgtcagtag ccaggagaaa tggggatggg ggaaatacga cttagtgagg 4300

 catagacatc cctggtccat cctttctgtc tccagctgtt tcttggaacc 4350

 tgctctcctg cttgctggtc cctgacgcag agaccgttgc ctcccccaca 4400

 gccgtttgac tgaaggctgc tctggagacc tagagtaaaa cggctgatgg 4450

 aagttgtggg acccacttcc atttccttca gtcattagag gtggaaggga 4500

 ggggtctcca agtttggaga ttgagcagat gaggcttggg atgcccctgc 4550

 tttgacttca gccatggatg aggagtggga tggcagcaag gtggctcctg 4600

 tggcagtgga gttgtgccag aaacagtggc cagttgtatc gcctataaga 4650

 cagggtaagg tctgaagagc tgagcctgta attctgctgt aataatgata 4700

 gtgctcaaga agtgccttga gttggtgtac agtgccatgg ccatcaagaa 4750

 tcccagattt caggttttat tacaaaatgt aagtggtcac ttggcgattt 4800

 tgtagtacat gcatgagtta ccttttttct ctatgtctga gaactgtcag 4850

 attaaaacaa gatggcaaag agatcgttag agtgcacaac aaaatcacta 4900

 tcccattaga cacatcatca aaagcttatt tttattcttg cactggaaga 4950

 atcgtaagtc aactgtttct tgaccatggc agtgttctgg ctccaaatgg 5000

 tagtgattcc aaataatggt tctgttaaca ctttggcaga aaatgccagc 5050

 tcagatattt tgagatacta aggattatct ttggacatgt actgcagctt 5100

 cttgtctctg ttttggatta ctggaatacc catgggccct ctcaagagtg 5150

 ctggacttct aggacattaa gatgattgtc agtacattaa acttttcaat 5200

 cccattatgc aatcttgttt gtaaatgtaa acttctaaaa atatggttaa 5250

 taacattcaa cctgtttatt acaacttaaa aggaacttca gtgaatttgt 5300

 ttttattttt taacaagatt tgtgaactga atatcatgaa ccatgttttg 5350

 ataccccttt ttcacgttgt gccaacggaa tagggtgttt gatatttctt 5400

 catatgttaa ggagatgctt caaaatgtca attgctttaa acttaaatta 5450

 cctctcaaga gaccaaggta catttacctc attgtgtata taatgtttaa 5500

 tatttgtcag agcattctcc aggtttgcag ttttatttct ataaagtatg 5550

 ggtattatgt tgctcagtta ctcaaatggt actgtattgt ttatatttgt 5600

 accccaaata acatcgtctg tactttctgt tttctgtatt gtatttgtgc 5650

 aggattcttt aggctttatc agtgtaatct ctgcctttta agatatgtac 5700

 agaaaatgtc catataaatt tccattgaag tcgaatgata ctgagaagcc 5750

 tgtaaagagg agaaaaaaac ataagctgtg tttccccata agttttttta 5800

 aattgtatat tgtatttgta gtaatattcc aaaagaatgt aaataggaaa 5850

 tagaagagtg atgcttatgt taagtcctaa cactacagta gaagaatgga 5900

 agcagtgcaa ataaattaca tttttcccaa gtgccagtgg catattttaa 5950

 aataaagtgt atacgttgga atgagtcatg ccatatgtag ttgctgtaga 6000

 tggcaactag aacctttgag ttacaagagt ctttagaagt tttctaaccc 6050

 tgcctagtgc aagttacaat attatagcgt gttcggggag tgccctcctg 6100

 tctgcaggtg tgtctctgtg cctgggggct tttctccaca tgcttagggg 6150

 tgtgggtctt ccattggggc atgatggacc tgtctacagg tgatctctgt 6200

 tgcctttggg tcagcacatt tgttagtctc ctgggggtga aaacttggct 6250

 tacaagagaa ctggaaaaat gatgagatgt ggtccccaaa cccttgattg 6300

 actctgggga ggggctttgt gaataggatt gctctcacat taaagatagt 6350

 tacttcaatt tgaaggctgg atttagggat tttttttttt tccttataac 6400

 aaagacatca ccaggatatg aagcttttgt tgaaagttgg aaaaaaagtg 6450

 aaattaaaga cattcccaga caaatactaa gacaatttgt tgcctatgga 6500

 cgtctgcct 6509

<210> 5955
<211> 503
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3682, 3696, 3699-3700
<223> Unknown amino acid

<400> 5955
 Met Glu Ala Ala Val Ala Ala Pro Arg Pro Arg Leu Leu Leu Leu
   1               5                  10                  15

 Val Leu Ala Ala Ala Ala Ala Ala Ala Ala Ala Leu Leu Pro Gly
                  20                  25                  30

 Ala Thr Ala Leu Gln Cys Phe Cys His Leu Cys Thr Lys Asp Asn
                  35                  40                  45

 Phe Thr Cys Val Thr Asp Gly Leu Cys Phe Val Ser Val Thr Glu
                  50                  55                  60

 Thr Thr Asp Lys Val Ile His Asn Ser Met Cys Ile Ala Glu Ile
                  65                  70                  75

 Asp Leu Ile Pro Arg Asp Arg Pro Phe Val Cys Ala Pro Ser Ser
                  80                  85                  90

 Lys Thr Gly Ser Val Thr Thr Thr Tyr Cys Cys Asn Gln Asp His
                  95                 100                 105

 Cys Asn Lys Ile Glu Leu Pro Thr Thr Val Lys Ser Ser Pro Gly
                 110                 115                 120

 Leu Gly Pro Val Glu Leu Ala Ala Val Ile Ala Gly Pro Val Cys
                 125                 130                 135

 Phe Val Cys Ile Ser Leu Met Leu Met Val Tyr Ile Cys His Asn
                 140                 145                 150

 Arg Thr Val Ile His His Arg Val Pro Asn Glu Glu Asp Pro Ser
                 155                 160                 165

 Leu Asp Arg Pro Phe Ile Ser Glu Gly Thr Thr Leu Lys Asp Leu
                 170                 175                 180

 Ile Tyr Asp Met Thr Thr Ser Gly Ser Gly Ser Gly Leu Pro Leu
                 185                 190                 195

 Leu Val Gln Arg Thr Ile Ala Arg Thr Ile Val Leu Gln Glu Ser
                 200                 205                 210

 Ile Gly Lys Gly Arg Phe Gly Glu Val Trp Arg Gly Lys Trp Arg
                 215                 220                 225

 Gly Glu Glu Val Ala Val Lys Ile Phe Ser Ser Arg Glu Glu Arg
                 230                 235                 240

 Ser Trp Phe Arg Glu Ala Glu Ile Tyr Gln Thr Val Met Leu Arg
                 245                 250                 255

 His Glu Asn Ile Leu Gly Phe Ile Ala Ala Asp Asn Lys Asp Asn
                 260                 265                 270

 Gly Thr Trp Thr Gln Leu Trp Leu Val Ser Asp Tyr His Glu His
                 275                 280                 285

 Gly Ser Leu Phe Asp Tyr Leu Asn Arg Tyr Thr Val Thr Val Glu
                 290                 295                 300

 Gly Met Ile Lys Leu Ala Leu Ser Thr Ala Ser Gly Leu Ala His
                 305                 310                 315

 Leu His Met Glu Ile Val Gly Thr Gln Gly Lys Pro Ala Ile Ala
                 320                 325                 330

 His Arg Asp Leu Lys Ser Lys Asn Ile Leu Val Lys Lys Asn Gly
                 335                 340                 345

 Thr Cys Cys Ile Ala Asp Leu Gly Leu Ala Val Arg His Asp Ser
                 350                 355                 360

 Ala Thr Asp Thr Ile Asp Ile Ala Pro Asn His Arg Val Gly Thr
                 365                 370                 375

 Lys Arg Tyr Met Ala Pro Glu Val Leu Asp Asp Ser Ile Asn Met
                 380                 385                 390

 Lys His Phe Glu Ser Phe Lys Arg Ala Asp Ile Tyr Ala Met Gly
                 395                 400                 405

 Leu Val Phe Trp Glu Ile Ala Arg Arg Cys Ser Ile Gly Gly Ile
                 410                 415                 420

 His Glu Asp Tyr Gln Leu Pro Tyr Tyr Asp Leu Val Pro Ser Asp
                 425                 430                 435

 Pro Ser Val Glu Glu Met Arg Lys Val Val Cys Glu Gln Lys Leu
                 440                 445                 450

 Arg Pro Asn Ile Pro Asn Arg Trp Gln Ser Cys Glu Ala Leu Arg
                 455                 460                 465

 Val Met Ala Lys Ile Met Arg Glu Cys Trp Tyr Ala Asn Gly Ala
                 470                 475                 480

 Ala Arg Leu Thr Ala Leu Arg Ile Lys Lys Thr Leu Ser Gln Leu
                 485                 490                 495

 Ser Gln Gln Glu Gly Ile Lys Met
                 500

<210> 5956
<211> 805
<212> DNA
<213> Homo sapien

<400> 5956
 ggcacgaggt ccctaattgt cttgtaccta gccctagggt gaccagggca 50

 ggggaatcat ggcgagaagc gtaagggcct gatgaagaag gtgtgctggg 100

 tgtgggctct agcccacttg gttttgtgtg agaggtggct gacagcaggt 150

 tgtttgctgt atgtaggagt tatccagccc tgcaagggca gtccctccag 200

 tgtctgcaaa gcccgaagat gtctgcatcc aaaatacaga ataaaaagat 250

 atggttacta caagtactca gtaagactga taatctgtca tcatcatcct 300

 catgccctta aagcagagct aactgatgat taatatatgc ttctatgtta 350

 acagtcttgg actttattaa tggtgggtgg aagttaactt aatgtatgta 400

 tgcaaactaa aaagtggcat ccttttcatt aatgacccaa ccattattca 450

 agagctatgt ctagttaggg acttcagact tttgaaagaa atgaagaaat 500

 aatgccagat acatgggctc gcacttggaa tcccagctac ttgggggacc 550

 gaggtgggag gaccgcttga gcccaggagt tcgagaccag cctgggcaac 600

 atagcgaaac cctgcctcag ttttaaaaaa gaaaaaaaga agtagtgaag 650

 aaattggaaa ggattctgag aagaaatatg caaggtggaa aagagcctag 700

 aaagaaaggt gacagatgct gggatttggt cgtcagaaga gatatctagg 750

 aaatagcatg gcagccctca agtactagct ccacttaaaa aaaaaaaaaa 800

 aaaaa 805

<210> 5957
<211> 83
<212> PRT
<213> Homo sapien

<400> 5957
 Met Lys Lys Val Cys Trp Val Trp Ala Leu Ala His Leu Val Leu
   1               5                  10                  15

 Cys Glu Arg Trp Leu Thr Ala Gly Cys Leu Leu Tyr Val Gly Val
                  20                  25                  30

 Ile Gln Pro Cys Lys Gly Ser Pro Ser Ser Val Cys Lys Ala Arg
                  35                  40                  45

 Arg Cys Leu His Pro Lys Tyr Arg Ile Lys Arg Tyr Gly Tyr Tyr
                  50                  55                  60

 Lys Tyr Ser Val Arg Leu Ile Ile Cys His His His Pro His Ala
                  65                  70                  75

 Leu Lys Ala Glu Leu Thr Asp Asp
                  80

<210> 5958
<211> 4485
<212> DNA
<213> Homo sapien

<400> 5958
 tgcgccgctg cgggagccac aggaagtgaa gagcttccgc cgggagaccg 50

 cggctgcagg aacggaggcg gaaggggccc tgcggcgacg acgtcgtcga 100

 cgggggtggc cgtgggagct gagcacggag aagactccct ctctcggaag 150

 ccggatcccg agccgggcag gatggatcac caccagccgg ggactgggcg 200

 ctaccaggtg cttcttaatg aagaggataa ctcagaatca tcggctatag 250

 agcagccacc tacttcaaac ccagcaccgc agattgtgca ggctgcgtct 300

 tcagcaccag cacttgaaac tgactcttcc cctccaccat atagtagtat 350

 tactgtggaa gtacctacaa cttcagatac agaagtttac ggtgagtttt 400

 atcccgtgcc acctccctat agcgttgcta cctctcttcc tacatacgat 450

 gaagctgaga aggctaaagc tgctgcaatg gcagctgcag cagcagaaac 500

 atctcaaaga attcaggagg aagagtgtcc accaagagat gacttcagtg 550

 atgcagacca gctcagagtg gggaatgatg gcattttcat gctggcattt 600

 ttcatggcat ttattttcaa ctggcttgga ttttgtttat ccttctgtat 650

 caccaatacc atagctggaa ggtatggtgc tatctgcgga tttggccttt 700

 ccttgatcaa atggatcctt attgtcaggt tttctgatta ttttactgga 750

 tatttcaatg gacagtattg gctttggtgg atatttcttg tacttggcct 800

 gctccttttc ttcagaggat ttgttaatta tctaaaagtc agaaacatgt 850

 ctgaaagtat ggcagctgct catagaacaa ggtatttctt cttattgtag 900

 agactgcatc aacccgacat tcctttctta taccaatgtg aaatttccag 950

 atcatctgta aacctacaac tttaatagaa gactactaat aacagaagac 1000

 aaattagtga agaaaagaca gagtttcgaa attgaatggc agggtggttt 1050

 ttgcttacaa gccatttctg ttcattcttt aagtatctat atttcatttg 1100

 ttttgcacat atgcatatgt gcccatttaa gatatttgca tatacttgat 1150

 agaaaccata aagttgtagc agttaagtcc agtcacattt ggttaatcag 1200

 tgtttgatat aattgaaaga gttgagtgga taaacagtct tccagcttgt 1250

 aaatgccatt gacttctgac ctgacattta gtataataaa aatgaaattc 1300

 ttaaccatgt caaatgattt agtttctggc tcttagactc atctggcagt 1350

 tctacacatg aaacatcttt tgttatataa ggtgtattga aacctgcagt 1400

 gctgattatt agaaaggatt tgtcagattt ttgaacatga tatttacatt 1450

 attatttagg aaaactcttc ctgtaaataa ccatgcataa cttactttct 1500

 gcaatgtttt cttagaaatt gtgtccagat agctttcact aattttaaat 1550

 taagtgaact aaatatatat gtgtatatgt atacacatat atatacacac 1600

 acacatatat atatttagaa acgtgagtgt taaagataga atttgtttta 1650

 ggacaaattt taagaaaatg tgggaatacc aaatgtcctt tataagaaaa 1700

 ataaatttta ttttaaggga catactagtt ttagggattt tcagatggga 1750

 agctgcattt ttaggattgc ccatcttaag agatcttgca ggaagagatt 1800

 gtattagata ttatatttat ttcatttaag ataattttca aagttaattt 1850

 tctaaataag ataattctca tttgtgtttg tcttttaaaa ggccaataaa 1900

 atatctttca gtatcattgt aataattttt tagagtttaa tttgtaaagc 1950

 ttagcaaata aaatcttgta ctatgaatag cttcttgctt tatgacttta 2000

 ggattaactt gtaaaaaaca tatcctgaac tgagatatgc aaaatactca 2050

 ttttcaagtt atggaaatgt gtttgtggca tataggactg tggggtctgt 2100

 gtgtgtagtg agagtgtgta gccactatta taactggaat ttaatttaca 2150

 ttcataaact actatatttc ccatcttgca aatcatttta tgtctcatct 2200

 gtttttcctt tcggttatat ctttggtttt gaataccaac atttaaaatg 2250

 atggtatttt atcttttaaa cttaaaaatt atttaataca gctatatgga 2300

 ccttataaaa ttgatttctt atttattatt agacattact actaaaaggt 2350

 acatctaact attcagggac atttttccat ttccaaaaaa taaaatttat 2400

 tatgctttat aacctcttct gtattttcta attttttcat tgtctttgat 2450

 aaataaaaca gttttgtttt gctaatatag cctatttttt gttttgtctc 2500

 attcagttta ctttcctgcg tagaattttt attgttatat taaaattttt 2550

 attgttgtat taaagtacct gtgttacacc ccttgaagta agacagtagc 2600

 atggggtaaa gaaaaaatat ttagtttagt tgcctaattt ggaagttaat 2650

 taaaattaaa ctgtactaat aacatattca aactcatgct ggatctcttt 2700

 catattaatt tcttatagac ctgtacttta ttctttcaat aatttttaaa 2750

 tgaaattaag ctttgctaca tggtaattaa ataattacta ggaagcttag 2800

 ctatcaaaca tcgacttact aaaatttcat tttagctttt atggtatatg 2850

 tgcttgtttt ctgaatatgg atacatgtta cttttgatcc agcatcaaaa 2900

 cttcactttt tgttttgact tttcccccca aatctgtaag gttcaagtat 2950

 acatattact gaatcctcta taattggcat aattcaatgg tagccttaaa 3000

 tctcatcatg taagcagggg aatcagaatg ttattttcaa gaacttaatg 3050

 ttcccttcag atatataaaa tcctgcatac ttcatttcct gtgagcttga 3100

 acagctgctg ttgtgttttg gggatgcttg atcatctttg cactctgcct 3150

 taaagattga aaaatcaaaa ctcttgttag ggtatctaaa catttttgag 3200

 tgtgaactgg ggattggaag ttaatacaaa aaatttcaaa ttatttctat 3250

 tgtaaatgaa taagctagtc atggctagga taatccattt tcatgtattt 3300

 atgcaataaa ctgaatttta aggcaaaaac aacacttttc tatatagtgt 3350

 atgcaggaca gattttagaa acttagatta aaatacaaat cccattacat 3400

 ttggttaaaa tgaaaatctc tgcttaatgg aaaaaatact aatctttagc 3450

 ctattttgag tctataagat atatttcatt ttagacatgc cttctaagtt 3500

 gttcacagat ttttacctgc taaaacaata ttatttccag taaaacctct 3550

 cctaacagga aaagtggagt tcaaaatatc caattggaga aaaattcaga 3600

 gttccttcat taaatataat ttttttcatc tagtatgtac tatttcaaga 3650

 agtgcaaaaa gtaatgatag tgaatgtgat accatactta actaaggtaa 3700

 tatatatcct tagtttgctc aaaagagtcc tggttattcc tgttttctca 3750

 gcttaatagt gcctcatcgt actctcaaaa gtgttctaat ttggaggata 3800

 agttatatga tcatcctgtg tataattgta gactgtacca agaagcaact 3850

 accttagctc cactgccctt tgagggatgg aactggggta agggcaggag 3900

 ccagttatta ttgccacagt gttttctaat gaaccatttg gcctgtagaa 3950

 gaggaatagt atttttttta atagttgtat ttgaatgatt ccagcttatc 4000

 gtaaatacta aactgaatgg cttttatatt tttaactgct gttaaatgtt 4050

 attttagcat ttattagttg tttattattt aattcttcaa atagtcatat 4100

 gaaaacatat atttgataaa ggtcaattgt tagatgataa tgtgccattc 4150

 attatcatag gaatgtcctt gcccatatat aaaacatgct ggcatgtatt 4200

 ttacttgtta ataaagttgt atagatgtgg aagtgtgaac ctgtgatgca 4250

 tccttttcaa aatcagttta agattcgcat attatcatga ctgtgacctc 4300

 actaaactgt ttatgtgaca aacctttcaa gattggagat gaaaacaaca 4350

 cttgtgaaat taggttgggg ttgcaacatc ttttaacttc tcagttattt 4400

 gtatgtcagg agacagattg tggtttaatt ttaataaaca aaatatcatc 4450

 tttttgaaaa taaaaaaaaa aaaagggcgg ccgct 4485

<210> 5959
<211> 242
<212> PRT
<213> Homo sapien

<400> 5959
 Met Asp His His Gln Pro Gly Thr Gly Arg Tyr Gln Val Leu Leu
   1               5                  10                  15

 Asn Glu Glu Asp Asn Ser Glu Ser Ser Ala Ile Glu Gln Pro Pro
                  20                  25                  30

 Thr Ser Asn Pro Ala Pro Gln Ile Val Gln Ala Ala Ser Ser Ala
                  35                  40                  45

 Pro Ala Leu Glu Thr Asp Ser Ser Pro Pro Pro Tyr Ser Ser Ile
                  50                  55                  60

 Thr Val Glu Val Pro Thr Thr Ser Asp Thr Glu Val Tyr Gly Glu
                  65                  70                  75

 Phe Tyr Pro Val Pro Pro Pro Tyr Ser Val Ala Thr Ser Leu Pro
                  80                  85                  90

 Thr Tyr Asp Glu Ala Glu Lys Ala Lys Ala Ala Ala Met Ala Ala
                  95                 100                 105

 Ala Ala Ala Glu Thr Ser Gln Arg Ile Gln Glu Glu Glu Cys Pro
                 110                 115                 120

 Pro Arg Asp Asp Phe Ser Asp Ala Asp Gln Leu Arg Val Gly Asn
                 125                 130                 135

 Asp Gly Ile Phe Met Leu Ala Phe Phe Met Ala Phe Ile Phe Asn
                 140                 145                 150

 Trp Leu Gly Phe Cys Leu Ser Phe Cys Ile Thr Asn Thr Ile Ala
                 155                 160                 165

 Gly Arg Tyr Gly Ala Ile Cys Gly Phe Gly Leu Ser Leu Ile Lys
                 170                 175                 180

 Trp Ile Leu Ile Val Arg Phe Ser Asp Tyr Phe Thr Gly Tyr Phe
                 185                 190                 195

 Asn Gly Gln Tyr Trp Leu Trp Trp Ile Phe Leu Val Leu Gly Leu
                 200                 205                 210

 Leu Leu Phe Phe Arg Gly Phe Val Asn Tyr Leu Lys Val Arg Asn
                 215                 220                 225

 Met Ser Glu Ser Met Ala Ala Ala His Arg Thr Arg Tyr Phe Phe
                 230                 235                 240

 Leu Leu


<210> 5960
<211> 3668
<212> DNA
<213> Homo sapien

<400> 5960
 ggcagagggt gggccttagg acgggtctcc cttaaactgg gcgatcaggc 50

 agcgacccta gaggcgtctg tagggtaaag ctgggggttc tgtagccgga 100

 ggcggcggcg agtccagaac gtcctggcct tacagggaga aggcgtcact 150

 cgcggttaca agtgcctgac cctcactcca gttggcggag gaggagaagg 200

 aaggggccgg gccgggtccc ctcccctcgc gccccggatg gatgtgcccg 250

 gcccggtgtc tcggcgggcg gcggcggcgg cggccactgt gctcctgcgg 300

 accgctcggg tccgtcgcga atgctggttc ttgccgaccg cgctgctctg 350

 cgcctacggc ttcttcgcca gcctcaggcc gtccgagccc ttcctgaccc 400

 cgtacctgct ggggccggac aagaacctga ccgagaggga ggtcttcaat 450

 gaaatttatc cagtatggac ttactcttac ctggtgctac tgtttcctgt 500

 gttccttgcc acagactacc tccgttataa acctgttgtt ctactgcagg 550

 ggctcagcct tattgttaca tggtttatgc tgctctatgc ccagggactg 600

 ctggccattc aatttctaga atttttttat ggcatcgcca cagccactga 650

 aattgcctat tactcttata tctacagtgt ggtggacctg ggcatgtacc 700

 agaaagtcac aagttactgt cgaagtgcca ctttggtggg ctttacagtg 750

 ggctctgtcc tagggcaaat ccttgtctca gtggcaggct ggtcgctgtt 800

 cagcctgaat gtcatctctc ttacctgtgt ttcagtggct tttgctgtgg 850

 cctggttttt acctatgcca cagaagagcc tcttctttca ccacattcct 900

 tctacctgcc agagagtgaa tggcatcaag gtacaaaatg gtggcattgt 950

 tactgacacc ccagcttcta accaccttcc tggctgggag gacattgagt 1000

 caaaaatccc tctaaatatg gaggagcctc ccgtggagga accggaaccc 1050

 aagccagacc gtctccttgt attgaaagta ctatggaatg atttcctgat 1100

 gtgctactcc tctcgccctc ttctctgctg gtctgtgtgg tgggccctct 1150

 ctacctgtgg ctattttcaa gttgtgaact acacacaggg cctgtgggag 1200

 aaagtgatgc cttctcgcta tgctgctatc tataatggtg gcgtggaggc 1250

 cgtttcaacc ttactgggtg ctgttgctgt gtttgcagtt ggttatataa 1300

 aaatatcctg gtcaacttgg ggagaaatga cattatctct cttttctctc 1350

 ctgattgctg ctgcagtgta tatcatggac actgtgggta acatttgggt 1400

 gtgctatgca tcctatgttg tcttcagaat catctacatg ttactcatca 1450

 cgatagcaac ttttcaaatt gctgcaaacc tcagcatgga acgctatgcc 1500

 ctagtatttg gtgtaaatac cttcattgcc ctggcactgc agacgctgct 1550

 cactctaatt gtggtagatg ccagtggcct tggattagaa attaccactc 1600

 agtttttgat ctatgccagt tattttgcac tcatcgctgt ggttttcctg 1650

 gccagtggtg cagtcagtgt tatgaagaaa tgtagaaagc tggaagatcc 1700

 acaatcaagt tctcaagtaa ccacttcata atatactgct gaagggcttc 1750

 ttcttatagc aagaactctg cacagcaact gcctggatgt atttgatttt 1800

 ttaaagcgta gacatatatt tatgaatgtg catttcttga cttcacagca 1850

 gccacttgac taataccttg tgttccggga ataacatgat actattcaga 1900

 ggagccagaa gtaaagttta tttcatggat tatttatgag agctaattta 1950

 aggatgactt tttttctgat tcaaaagtga acttgatttt aaaaaccagt 2000

 caagagcaat caaagcagca catggtgttg tatacttcat tagcaagtga 2050

 gtttggtgtt ttataggtca catatgtctg tatctactta gccagatgct 2100

 tggcctggtg ggaccagggc tccacagagg ccacaaaatg ttgcaagtca 2150

 tgatggatgg aaatatgttc taacagcatc tgcctctatt caatttaatt 2200

 cttatttctg tgttactcat gtacattggt ctttctacat agttattcta 2250

 tcactggcaa tatttgttct ggtttagtgt tctgtatttt aaggtgtacg 2300

 tatcatttct aattttaagt tattttaaaa aaattcatca tatgaatgtt 2350

 cttggttccc attgtgacga ttatttattt ctgtaaaatt tgtttagaag 2400

 tacgtttttg cattattcat atgcttccca gagaagctca tttagttaga 2450

 aaataaggca agttttgaag cctgctaaat gaagagactt aagaaagctt 2500

 aaggtacgct tgcttgtctt taaatcttca atatgaagga ctattaattc 2550

 caagattaaa agttcatata taggctaaag atgtaactag gccatttgta 2600

 tttgtattcc cttttatttc caaaataaaa tgaaaaatct ttttttaata 2650

 atttcatccc tatttatagt ttttatatta atttgttttt cttatccaag 2700

 taaagatgtc aataggaatt gcattagtcc aaggcctttt tcataaactg 2750

 agcctctttt caattatttc aatgggacag gaactaggat agatgtgatt 2800

 cctgcatttt tttaccttaa atctgccttt gtttctaaag gtagatcatc 2850

 ttgaatattt gcttaaaatt gctagtgatt tcattaccaa gttacttgaa 2900

 aaaatgttct atatgcattt aattctgaaa tcagtctacc aaggggctgc 2950

 tagtatatgt cagacatgaa aactatttta aagctgactt tgttgcctta 3000

 tcttgaaaag aatctagata ggtgctttta actggggtat taactttttt 3050

 agaatgacac agctgaacag tgttaataat agtgtgtcaa gattgcaaag 3100

 tcgacatact catttggttt aagcaggaat cctagaagca aatggatggg 3150

 gataagaata ggtcattttc tattcaccat cctttactat taagggaaag 3200

 gaaaagaaca ctagctaagg aagggaaagg gaagtgatat cataaaagta 3250

 gcaaccttca ttttacattc tgtctgtttt tctttttttg ctttgttttg 3300

 tttgtgctaa tttgggaatt gtgtactccg aaacaagtag aaaagtgctg 3350

 tttgagggat tttattaaat ctttttttaa tggaatgtgg tacaaattgt 3400

 tcatgttacc aaagcaatat ttccctggaa tttaattcaa agtttgtggc 3450

 atacaacctg agccttttct tatataagac aagaatatgt tcacatcttg 3500

 gtatgtggcc atatttatag aatgctgaac tcaatgtgca agttgtactg 3550

 tatgcagttt tgtaaataag tgaaaataat ttgttgtact ttttattcaa 3600

 ttctgtatag attataaaat tatttttatt aaataaatat tttacagtat 3650

 aaaaaaaaaa aaaaaaaa 3668

<210> 5961
<211> 497
<212> PRT
<213> Homo sapien

<400> 5961
 Met Asp Val Pro Gly Pro Val Ser Arg Arg Ala Ala Ala Ala Ala
   1               5                  10                  15

 Ala Thr Val Leu Leu Arg Thr Ala Arg Val Arg Arg Glu Cys Trp
                  20                  25                  30

 Phe Leu Pro Thr Ala Leu Leu Cys Ala Tyr Gly Phe Phe Ala Ser
                  35                  40                  45

 Leu Arg Pro Ser Glu Pro Phe Leu Thr Pro Tyr Leu Leu Gly Pro
                  50                  55                  60

 Asp Lys Asn Leu Thr Glu Arg Glu Val Phe Asn Glu Ile Tyr Pro
                  65                  70                  75

 Val Trp Thr Tyr Ser Tyr Leu Val Leu Leu Phe Pro Val Phe Leu
                  80                  85                  90

 Ala Thr Asp Tyr Leu Arg Tyr Lys Pro Val Val Leu Leu Gln Gly
                  95                 100                 105

 Leu Ser Leu Ile Val Thr Trp Phe Met Leu Leu Tyr Ala Gln Gly
                 110                 115                 120

 Leu Leu Ala Ile Gln Phe Leu Glu Phe Phe Tyr Gly Ile Ala Thr
                 125                 130                 135

 Ala Thr Glu Ile Ala Tyr Tyr Ser Tyr Ile Tyr Ser Val Val Asp
                 140                 145                 150

 Leu Gly Met Tyr Gln Lys Val Thr Ser Tyr Cys Arg Ser Ala Thr
                 155                 160                 165

 Leu Val Gly Phe Thr Val Gly Ser Val Leu Gly Gln Ile Leu Val
                 170                 175                 180

 Ser Val Ala Gly Trp Ser Leu Phe Ser Leu Asn Val Ile Ser Leu
                 185                 190                 195

 Thr Cys Val Ser Val Ala Phe Ala Val Ala Trp Phe Leu Pro Met
                 200                 205                 210

 Pro Gln Lys Ser Leu Phe Phe His His Ile Pro Ser Thr Cys Gln
                 215                 220                 225

 Arg Val Asn Gly Ile Lys Val Gln Asn Gly Gly Ile Val Thr Asp
                 230                 235                 240

 Thr Pro Ala Ser Asn His Leu Pro Gly Trp Glu Asp Ile Glu Ser
                 245                 250                 255

 Lys Ile Pro Leu Asn Met Glu Glu Pro Pro Val Glu Glu Pro Glu
                 260                 265                 270

 Pro Lys Pro Asp Arg Leu Leu Val Leu Lys Val Leu Trp Asn Asp
                 275                 280                 285

 Phe Leu Met Cys Tyr Ser Ser Arg Pro Leu Leu Cys Trp Ser Val
                 290                 295                 300

 Trp Trp Ala Leu Ser Thr Cys Gly Tyr Phe Gln Val Val Asn Tyr
                 305                 310                 315

 Thr Gln Gly Leu Trp Glu Lys Val Met Pro Ser Arg Tyr Ala Ala
                 320                 325                 330

 Ile Tyr Asn Gly Gly Val Glu Ala Val Ser Thr Leu Leu Gly Ala
                 335                 340                 345

 Val Ala Val Phe Ala Val Gly Tyr Ile Lys Ile Ser Trp Ser Thr
                 350                 355                 360

 Trp Gly Glu Met Thr Leu Ser Leu Phe Ser Leu Leu Ile Ala Ala
                 365                 370                 375

 Ala Val Tyr Ile Met Asp Thr Val Gly Asn Ile Trp Val Cys Tyr
                 380                 385                 390

 Ala Ser Tyr Val Val Phe Arg Ile Ile Tyr Met Leu Leu Ile Thr
                 395                 400                 405

 Ile Ala Thr Phe Gln Ile Ala Ala Asn Leu Ser Met Glu Arg Tyr
                 410                 415                 420

 Ala Leu Val Phe Gly Val Asn Thr Phe Ile Ala Leu Ala Leu Gln
                 425                 430                 435

 Thr Leu Leu Thr Leu Ile Val Val Asp Ala Ser Gly Leu Gly Leu
                 440                 445                 450

 Glu Ile Thr Thr Gln Phe Leu Ile Tyr Ala Ser Tyr Phe Ala Leu
                 455                 460                 465

 Ile Ala Val Val Phe Leu Ala Ser Gly Ala Val Ser Val Met Lys
                 470                 475                 480

 Lys Cys Arg Lys Leu Glu Asp Pro Gln Ser Ser Ser Gln Val Thr
                 485                 490                 495

 Thr Ser


<210> 5962
<211> 5932
<212> DNA
<213> Homo sapien

<400> 5962
 ggggcactga ggagcggcgc ccgcggggca gcgaggagcc cgatgcaggg 50

 ttctgcgcgt catttccggt cccgcgggcg ccccgtgaag cccacctgga 100

 tccgccagcg ctgtgccact ccccagtgcc gagctccgag ctgtctccgc 150

 ggcctcgcgc ccggcccctc caccgcgcac ctcttaggcc ccgcccgcca 200

 gcgtcccttt gttgtgaagg cgccggggcc tagcgctatg cctgcggcgg 250

 agactgcatc aggctctcgc gtctgcttct gcgctttgcc tgggagaggc 300

 cctggtggcc tcgttcctgg cgcccggagt ccctgctgcg gccccacccc 350

 cgggcggtca cggtgaccca tgctgcccag cctggaggta aaatcgttcg 400

 tggctgtggc ttcagcatgt cgtcctcggt gaaaacccca gcactggaag 450

 agctggttcc tggctccgaa gagaagccga aaggcaggtc gcctctcagc 500

 tggggctctc tgtttggtca ccgaagtgag aagattgttt ttgccaagag 550

 cgacggcggc acagatgaga acgtactgac cgtcaccatc acggagacca 600

 cggtcatcga gtcagacttg ggtgtgtgga gctcgcgggc gctgctctac 650

 ctcacgctgt ggttcttctt cagcttctgc acgctcttcc tcaacaagta 700

 catcctgtcc ctgctgggag gcgagcccag catgctaggt gcggtgcaga 750

 tgctgtccac cacggttatc gggtgtgtga aaaccctcgt tccttgctgt 800

 ttgtatcagc acaaggcccg gctttcctac ccacccaact tccttatgac 850

 gatgctgttt gtgggtctga tgaggtttgc aactgtggtt ttgggtttgg 900

 tcagcctgaa aaatgtggcg gtttcgtttg ctgagacggt gaagagctcc 950

 gcccccatct tcacggtgat catgtctcgg atgattctgg gggagtacac 1000

 agggctgctg gtcaacctct ccctcatccc agtcatgggc gggctggcgc 1050

 tgtgcacggc cactgagatc agcttcaatg tcctggggtt ctcggccgca 1100

 ctgtccacca acatcatgga ctgtttgcaa aatgtttttt caaaaaagct 1150

 gctcagcggg gacaaataca ggttctcggc cccggagctg cagttctaca 1200

 ccagcgccgc tgcggtggcc atgctcgtcc cggcccgggt tttctttacg 1250

 gacgtcccag tgatcgggag gagcgggaag agcttcagct acaaccagga 1300

 cgtggtgctg ctgcttctga cagacggagt cctgttccac cttcagagcg 1350

 tcacggcgta cgccctcatg gggaaaatct ccccggtgac tttcagcgtc 1400

 gccagcaccg tgaaacatgc cttgtccatc tggctcagcg taatcgtttt 1450

 cggcaacaag atcaccagct tgtcggccgt tggcacagcc ctggtgaccg 1500

 ttggggtcct gctctacaac aaagccaggc aacaccagca ggaggcgctg 1550

 cagagcctgg ctgcagccac tggccgggcc ccagacgaca cagtggagcc 1600

 gctgcttcca caggacccca ggcagcatcc ctgagagcag gaagctgcca 1650

 gctgctgctg tcctcgtgac actgcatccc ccagaaatgg gcagggacgc 1700

 cctcctccat ggccctgctg gggtgcagga catggggagc taagttggcc 1750

 attgcctgcg gctttctcgg tttgtcggtg aagaccagca gaaactcaaa 1800

 ctggggattc caggtatcag cttcctggag tagacaccag accagtagct 1850

 gactgtgtcc gccgagccca tccccgtgta atgtgaaaac agcctctgag 1900

 gctcccatgc tgggggtgcc cacttcctct ctgggcgaca ccccagggtc 1950

 caccgggagc cagaggtggg tccagtgcca acgagagccg ctccctgcca 2000

 cagccaagag agccctcggc ttcccacacc agccatcgaa ggccctgagg 2050

 ccctggaccg gcggcagact ggccctgggc atgaggccac agagcagggc 2100

 cgaagggagg ggacagaggg ccctggaagg aagggtctcc tgctgccacg 2150

 gtgggcactc agaacttctc cccacctgac ccagggctgt gggcatcctc 2200

 agactatccc agaggcatcg caagcctcaa gctgcagcat tgcacggcac 2250

 tcaagggcta tgaccacgga ggccgttcag tcgcttctgt ttagaggaag 2300

 gccccctacc tcttccacac cctgccctcc tatcccttcc acaccctggg 2350

 ctgcatgagc tccccgcaac cccagggcac cctgccctcc tacctgtggg 2400

 ggtttccagc cctgaggttg aggacaaacc tctcgtgttt aacttgggag 2450

 gagatgtgta cgttcctttt cttttttgga ctctgagtat gaggcaggct 2500

 gttctgaggt ccccgtgggg tgagcctgtc tgtcctccct cagagcccac 2550

 cgttcctatc atcatctagc acctgtccgg ttccccacgt gagccttggg 2600

 caggacgctg cagtgttgat ggtttgggtt acgtggcgtt tacctgggcg 2650

 ccgtccttgc tgaaaaagga aacgtccaca ctgaatgttt ctggggcgcg 2700

 tggtgtgtgt caggcgccca ccctgtccca ctctccccaa gggacagtag 2750

 tacggcacac tggggccacc agccagctca actcatcctc ctgtgtcacg 2800

 cacccccgag ggcgcaggag gcctgaggag tggctactgg agccgtgtgt 2850

 taggcagagg cttctgacca tgtctgagct ctttaccccc aatctcgcaa 2900

 ccggcggatt cccatgcccg gtgcagcctg ttgccagcca gcctttgaga 2950

 cccagagctc cagggcttgt cagaggcagc atggggctcc agtggtcccg 3000

 agtctcattt ccctgcctgc tctttaggcc tttggcaccc atggtcactt 3050

 cactggtttt ccatttggct tctcacctgg gaaatacaaa aatagcccct 3100

 cctgaagata aaatcgttca gaaacagagc aataattctg actcattaac 3150

 ttctacctac tcaaaaaagt ctgccatgat gatggaccga agtgaggctt 3200

 tttaacccac aagtaacctt tttatttttt tgagacggtc ttgctctgtc 3250

 acccaggctg gagtgcagtg gcatgatctt ggctcgctgc agcctcgact 3300

 tcctgggctc aagtgatcca cctcagcctc ccatgtggct ggaaccgcag 3350

 gcacgtgcca ccatgcctgg ctattttttt gttgagctgg gctctcgctt 3400

 tgttgcccag gctggtcttg aactcctcgg ctcaagcaat ccttcccact 3450

 cagcctcctg tagtgtcgag aatataggcg tgggctacta cacctgcttc 3500

 agccgcttct ataaaaccgc tgacctgtgt gtggaggaca ggccaggtgt 3550

 gtgctcactg cgctgcgaag atgttttgtc acgtgacttt ccctgggttt 3600

 ccatttcttt ttttctgctt tcctcaaaaa ctaatagaag accggctgcg 3650

 gtagctcagg cctctagtcc cagcactttg ggaggctgca gatggcggat 3700

 cacaaggcca ggagttcgag accagcctgg ccaacatgat gaaaccctgt 3750

 ctctaccaaa aatacaaaaa ttagctgggt gtgatggtgg gtgcctgtgg 3800

 tctcagctac tcaggaggct gaggcaggag aattgtttga gccccagagg 3850

 cggaggttgc agtgagccaa gatcgtgcca ttgcactcca gcctgggcaa 3900

 cagggcaaga ttccgtctca aaaacaaaca ctattagaaa atgctctgga 3950

 ggtggcgggg agttgttgat ttgtgaggac agattgaaag caactcccag 4000

 ggtggccttg tccacctccc catcgagaat atggctgccg gcctctttga 4050

 agattgtggt ctggcataag gagaggtgca ggcgcctggt tctgagcacc 4100

 ttggaatttc cagccgcaca gcatctggtg ccctcccctc caccctcaca 4150

 aggagctgcc atcctgtttg gattttctgt ttgtggacca gaaacaaacg 4200

 tttttccaaa ggattagcaa ataggttgat ttcctgtgta acgctgctct 4250

 ggggcctctt cctcatcctg gcagaaggag cctggagccc atgaggcagc 4300

 cagcactgtg cccttgctca gtcgtgctgt cccctccctc tccctcagtc 4350

 tcttctccat gcccaagtca gtttccagcc gctggtcttc atggcattcc 4400

 cagcacagct ggacaccaag aggcaaaacc caaggcctgg cttggccgtg 4450

 ttaacgattg tacagacatt tttttaaata actttgtgta atacttttct 4500

 agaatagtaa gttcttgttg aactgtcaca gatgagcttc taggaacaca 4550

 ccgggtgtgg ttacttccac tgggtgtgtc catggtcgtg gtctgtgcct 4600

 ttgtaaacaa acagaacact tgaaccacct tccgaattgg gtcatcggct 4650

 tctttacatt gatacttaga gatttgcagc tctctaactt tcaaggaaac 4700

 ttcccctact gaaaggcata aaaaggttaa aaaagaaaat ccgagagtcc 4750

 caattccctg tataacagca ttaaaataat ctgcctgcct ggaaagatga 4800

 gaacactgtt gcacaaccca aaatgtgttt ttaatttgtg aaaaattacc 4850

 atggtgagtc agacagtcat tttaaacagc tgaacagaga ctatcatcag 4900

 caaatagagc tcagctttgt agctgccttt aaaatccttg tcccaaatcc 4950

 ggtgagctct gcttgctgcc gccgcgctcc tgggtgatca ctcagacggg 5000

 tcagtgggaa taacgggcca acaagacagc tttttacatg tgtccaaagg 5050

 atggcctttc gaaggcctgg aagtatttca ctgttggaag aagtaaacaa 5100

 gaatgacatt ccagatggaa atagaattct ctctcttgcc tttgaccaac 5150

 atggtactaa ggggtttctt ctttcccaat gtatgtacgt gccctgctgg 5200

 gggccttact ttatagaatg agagcatccg agcttcccta atgaatctgg 5250

 ctagttctgt gtctggctga ggatacagga gtgggacatc cactctcgga 5300

 tccctcagag cacagaaacc ttcagctttg ctgtctctga agtatttcct 5350

 ccagtttccc tgcgggcccc tatgtttgag tttgatggct gctggatcct 5400

 cactcaacga aaactcggtt ggaaactgtt ccgcctggca gtcctttttt 5450

 gttgttttcc atctcatttc ccttccatct gaaagtggca ttcagctgac 5500

 ttgctcattt agactgttca cggagtctga atctgccaac gtggtgttgg 5550

 aggctccacc ttgaaaaggg ccacagtcag ggcaactttc cccatacagg 5600

 aaaacttgaa aattacatca acagtctacg tcacagccaa attatatttc 5650

 ctttatacca aacaaaacta tggagaacta aaagtacatc acacaaaacg 5700

 tttatagtgt tttgcatgtg acctatttca gtatttatat aactagatta 5750

 gtgctttcta gcaaacggtt ctgttaatta gcgagtcact gttgattctg 5800

 ctgtggtggt aagttgatac cgtgtaacta atcccgtgga tgcctcctcg 5850

 ttatttttgt ccaaacgaag cagccgtggt agtagctgtc tatgattctt 5900

 gctcagcaaa gtaaaataaa tgttaaatat gg 5932

<210> 5963
<211> 3958
<212> DNA
<213> Homo sapien

<400> 5963
 ggggggagac gagcaggtcc gcgacgctgc tgctgtgcct gctgggctgc 50

 cacgtctgga aggcggtgac aagacgctgc gggagcccgg cgccggagcc 100

 caagaggtga cgttaaaggt gcacatcagc gacgccagca cccaccagcc 150

 cgtagcagat gcgctcatcg agatcttcac caaccaggcc tccatagcct 200

 ctggcacctc ggggactgat ggcgtcgcct ttatcaagtt ccagtataag 250

 ctgggcagtc agttgattgt caccgcctcg aagcatgcct acgtgccaaa 300

 ctctgcccca tggaagccaa tccggttacc tgtattttcc tctctgagcc 350

 ttggcctgct tccagaacgc tctgccactc taatggtata tgaagatgtc 400

 gtccaaatag tatcaggatt ccaaggtgcc cggccacagc ctcgcgttca 450

 tttccagaga agggctctga ggttgcctga gaacaccagc tacagtgacc 500

 tgaccgcgtt tctcacggcc gccagctccc cttcggaggt ggacagtttt 550

 ccttatttgc gaggattaga cggaaatgga acaggaaaca gcaccaggca 600

 tgacctgacc ccagtcacag ccgtcagcgt ccacttgctg agcagtaatg 650

 gaacgccggt gctggtggat ggtcccatct atgtcactgt gcccctggcc 700

 acgcagagca gcctgaggca caatgcctat gtcgcggcgt ggcggtttga 750

 ccagaagctg ggaacgtggc tgaagagcgg tctgggtctt gtgcaccagg 800

 aaggcagcca gctgacgtgg acatacattg ccccccagtt ggggtactgg 850

 gtggccgcca tgtcccctcc catcccaggt cccgttgtaa cacaggacat 900

 taccacgtat cacacggtgt ttcttttggc cattttagga ggaatggctt 950

 tcatactttt ggttttgctg tgtctccttt tatattattg caggaggaag 1000

 tgcttgaaac ctcgtcagca ccacagaaaa ctgcagctcc ctgcaggact 1050

 ggagagttcc aaaagagacc agtccacgtc catgtcacac attaacttgc 1100

 tgttttcacg ccgagcgtca gaattccctg gcccgctgtc cgtcaccagc 1150

 cacggccgcc ccgaggcccc cggcacgaag gaactgatga gtggagtcca 1200

 tttggaaatg atgtctccgg gcggcgaagg ggacctgcac acccccatgc 1250

 tcaagctctc ctacagcacc tcccaggaat ttagctcccg ggaggagctc 1300

 ctctcttgca aggaagagga taaaagccag atctcctttg ataacctcac 1350

 tccaagtggg acgctgggga aagactacca taagtcagtg gaggtttttt 1400

 ccttaaaggc aagaaaatct atggaaagag aaggctacga gtcctcgggc 1450

 atgatgacta caggggtagt tacaacaccg tgctctcaca gcctttattt 1500

 gaaaagcagg acagagaagg tccagcctcc acgggaagca aactcaccat 1550

 tcaggaacat ctgtaccccg cgccttcatc acctgagaaa gaacagctgc 1600

 tggaccgcag acccactgaa tgtatgatgt cgcgatcagt agatcacctc 1650

 gagagaccta cgtccttccc acggcccggc cagttaatct gctgcagttc 1700

 tgtcgaccag gtcaatgaca gcgtttacag gaaagtactg cctgccttgg 1750

 tcatcccggc tcattatatg aaactccccg gggaccactc ctatgtcagc 1800

 cagcccctcg tcgtcccggc tgatcagcag cttgagatag aaagactaca 1850

 ggctgagctg tccaatcccc atgccgggat cttcccacac ccgtcctcac 1900

 agatccagcc ccagcccctg tcttcccagg ccatctctca gcagcacctg 1950

 caggatgcgg gcacccggga gtggagccct cagaacgcat ccatgtcgga 2000

 gtctctctcc atcccagctt ccctgaacga cgcggctttg gctcagatga 2050

 acagtgaggt gcagctcctg actgaaaagg ccctgatgga gcttgggggt 2100

 gggaagccgc ttccgcacac ccgggcgtgg ttcgtctcct tggatggcag 2150

 gtccaacgct cacgttagac attcatacat tgatctccaa agagctggaa 2200

 ggaacggaag taatgatgcc agtttggact ctggcgtaga tatgaatgaa 2250

 ccaaaatcag cccggaaggg aaggggagat gctttgtctc tgcagcagaa 2300

 ctacccgccc gtccaagagc accagcagaa agagcctcga gccccagaca 2350

 gcacggccta cacgcagctc gtgtacctgg atgacgtgga acagagtggt 2400

 agcgaatgtg ggaccacggt ctgtaccccc gaggacagtg ccctgcgatg 2450

 cttgttggag gggtcgagtc ggagaagtgg tggccagctg cccagcctgc 2500

 aggaggagac gaccagacgg actgcggatg ccccctcgga gccagcagcc 2550

 agcccccacc agagaagatc tgcccacgag gaagaggaag acgatgatga 2600

 tgatgaccaa ggagaagaca agaaaagccc ctggcagaaa cgggaggaga 2650

 ggcccctgat ggcgtttaac attaaatgag ctatcgcaga cccacctgac 2700

 tgtggaatat aaaattgcca aatatccttt ctcatggaag cgcgtacccg 2750

 ttcgtggagg aaacggaacg gcagcccagc cgtgggacgg acgtggacgt 2800

 ttactgcatt cctgtttgcc gtgtaaatgt tagaaaggaa ttaaagttat 2850

 tactcggaat aaaggatgac tttggcggat gtcgcccctg caaggaggtg 2900

 gctgaaagtg gtgtccagat gtccttccga ggactcggcg tatccgccac 2950

 cagggacatt aagaaaccgc acgtgatgtc gctatgctct aacgatcacc 3000

 tcagttctcc ctcggattct gggaacagat gaaacttttt gcatcgcttg 3050

 agtcattttt atcacaataa tcctactgtg aagctgtcgt tgagaactta 3100

 ggttggcacg tagcgtctca aggtatgcgt tctctcaaag gaaagctatg 3150

 catcgctgct tctttgtctg attttgctta gattttgctt tggttaggtt 3200

 gcgttttggg gtttgccttt ttttgttgtc gcttaaatgc aatttggttg 3250

 taaagatttg attcctttgt gttcatctgt tccgcttctc agcggtccat 3300

 ctcagcgtct cccttcagga accgctgagt gtcctctctt aacatccaag 3350

 ccttttaatg aaatcgtact gaaatctgta tcagctaaga gtcctccaat 3400

 cctggtccca ttaactccaa gtgccttttt gtcagtgaca acagacagtc 3450

 cctcgctttt tgttgttgtt ggttttctta acccctttaa tggaactgcc 3500

 tggattttat acagttatta aaggatgtct cttttgcttt aaactgcatg 3550

 ctgccaagtg ccatttgggg tcagcatcct cgtttcaaca cagtgtgctc 3600

 tctagttatc atgtgtaacg tgggttctgt ttagcgaaga tagactagag 3650

 gacacgttag agatgccctt ccctgctcca tccctgtggc accattatgg 3700

 ttttttggct gtttgtatat acggttacgt attaactctg gaatcctatg 3750

 ggctcatctt gctcacccaa tgtgggagtc tggtttgagc aagcgagctg 3800

 aatgtgacta ttaaaaaaaa tttaaaaaaa aaaaagaaaa tcttatgtac 3850

 tatccaaaag tgccagaatg actcttctgt gcattcttct taaagagctg 3900

 cttggttatc caaaaatgaa aattcaaaat aaactctgaa aaaaaaaaaa 3950

 aaaaaaaa 3958

<210> 5964
<211> 2320
<212> DNA
<213> Homo sapien

<400> 5964
 gctcagtggg ggcggctact gctcatgtga ttgtggagta gacagttgga 50

 agaagtaccc agtccatttg gagagttaaa actgtgccta acagaggtgt 100

 cctctgactt ttcttctgca agctccatgt tttcacatct tccctttgac 150

 tgtgtcctgc tgctgctgct gctactactt acaaggtcct cagaagtgga 200

 atacagagcg gaggtcggtc agaatgccta tctgccctgc ttctacaccc 250

 cagccgcccc agggaacctc gtgcccgtct gctggggcaa aggagcctgt 300

 cctgtgtttg aatgtggcaa cgtggtgctc aggactgatg aaagggatgt 350

 gaattattgg acatccagat actggctaaa tggggatttc cgcaaaggag 400

 atgtgtccct gaccatagag aatgtgattc tagcagacag tgggatctac 450

 tgctgccgga tccaaatccc aggcataatg aatgatgaaa aatttaacct 500

 gaagttggtc atcaaaccag ccaaggtcac ccctgcaccg actctgcaga 550

 gagacttcac tgcagccttt ccaaggatgc ttaccaccag gggacatggc 600

 ccagcagaga cacagacact ggggagcctc cctgatataa atctaacaca 650

 aatatccaca ttggccaatg agttacggga ctctagattg gccaatgact 700

 tacgggactc tggagcaacc atcagaatag gcatctacat cggagcaggg 750

 atctgtgctg ggctggctct ggctcttatc ttcggcgctt taattttcaa 800

 atggtattct catagcaaag agaagataca gaatttaagc ctcatctctt 850

 tggccaacct ccctccctca ggattggcaa atgcagtagc agagggaatt 900

 cgctcagaag aaaacatcta taccattgaa gagaacgtat atgaagtgga 950

 ggagcccaat gagtattatt gctatgtcag cagcaggcag caaccctcac 1000

 aacctttggg ttgtcgcttt gcaatgccat agatccaacc accttatttt 1050

 tgagcttggt gttttgtctt tttcagaaac tatgagctgt gtcacctgac 1100

 tggttttgga ggttctgtcc actgctatgg agcagagttt tcccattttc 1150

 agaagataat gactcacatg ggaattgaac tgggacctgc actgaactta 1200

 aacaggcatg tcattgcctc tgtatttaag ccaacagagt tacccaaccc 1250

 agagactgtt aatcatggat gttagagctc aaacgggctt ttatatacac 1300

 taggaattct tgacgtgggg tctctggagc tccaggaaat tcgggcacat 1350

 catatgtcca tgaaacttca gataaactag ggaaaactgg gtgctgaggt 1400

 gaaagcataa cttttttggc acagaaagtc taaaggggcc actgattttc 1450

 aaagagatct gtgatccctt tttgtttttt gtttttgaga tggagtcttg 1500

 ctctgttgcc caggctggag tgcaatggca caatctcggc tcactgcaag 1550

 ctccgcctcc tgggttcaag cgattctcct gcctcagcct cctgagtggc 1600

 tgggattaca ggcatgcacc accatgccca gctaatttgt tgtattttta 1650

 gtagagacag ggtttcacca tgttggccag tgtggtctca aactcctgac 1700

 ctcatgattt gcctgcctcg gcctcccaaa gcactgggat tacaggcgtg 1750

 agccaccaca tccagccagt gatccttaaa agattaagag atgactggac 1800

 taggtctacc ttgatcttga agattccctt ggaatgttga gatttaggct 1850

 tatttgagca ctacctgccc aactgtcagt gccagtgcat agcccttctt 1900

 ttgtctccct tatgaagact gccctgcagg gctgagatgt ggcaggagct 1950

 cccagggaaa aaggaagtgc atttgattgg tgtgtattgg ccaagttttg 2000

 cttgttgtgt gcttgaaaga aaatatctct gaccaacttc tgtattcgtg 2050

 gaccaaactg aagctatatt tttcacagaa gaagaagcag tgacggggac 2100

 acaaattctg ttgcctggtg gaaagaaggc aaaggccttc agcaatctat 2150

 attaccagcg ctggatcctt tgacagagag tggtccctaa acttaaattt 2200

 caagacggta taggcttgat ctgtcttgct tattgttgcc ccctgcgcct 2250

 agcacaattt tgacacacaa ttggaactta ctaaaaattt ttttttactg 2300

 ttaaaaaaaa aaaaaaaaaa 2320

<210> 5965
<211> 301
<212> PRT
<213> Homo sapien

<400> 5965
 Met Phe Ser His Leu Pro Phe Asp Cys Val Leu Leu Leu Leu Leu
   1               5                  10                  15

 Leu Leu Leu Thr Arg Ser Ser Glu Val Glu Tyr Arg Ala Glu Val
                  20                  25                  30

 Gly Gln Asn Ala Tyr Leu Pro Cys Phe Tyr Thr Pro Ala Ala Pro
                  35                  40                  45

 Gly Asn Leu Val Pro Val Cys Trp Gly Lys Gly Ala Cys Pro Val
                  50                  55                  60

 Phe Glu Cys Gly Asn Val Val Leu Arg Thr Asp Glu Arg Asp Val
                  65                  70                  75

 Asn Tyr Trp Thr Ser Arg Tyr Trp Leu Asn Gly Asp Phe Arg Lys
                  80                  85                  90

 Gly Asp Val Ser Leu Thr Ile Glu Asn Val Ile Leu Ala Asp Ser
                  95                 100                 105

 Gly Ile Tyr Cys Cys Arg Ile Gln Ile Pro Gly Ile Met Asn Asp
                 110                 115                 120

 Glu Lys Phe Asn Leu Lys Leu Val Ile Lys Pro Ala Lys Val Thr
                 125                 130                 135

 Pro Ala Pro Thr Leu Gln Arg Asp Phe Thr Ala Ala Phe Pro Arg
                 140                 145                 150

 Met Leu Thr Thr Arg Gly His Gly Pro Ala Glu Thr Gln Thr Leu
                 155                 160                 165

 Gly Ser Leu Pro Asp Ile Asn Leu Thr Gln Ile Ser Thr Leu Ala
                 170                 175                 180

 Asn Glu Leu Arg Asp Ser Arg Leu Ala Asn Asp Leu Arg Asp Ser
                 185                 190                 195

 Gly Ala Thr Ile Arg Ile Gly Ile Tyr Ile Gly Ala Gly Ile Cys
                 200                 205                 210

 Ala Gly Leu Ala Leu Ala Leu Ile Phe Gly Ala Leu Ile Phe Lys
                 215                 220                 225

 Trp Tyr Ser His Ser Lys Glu Lys Ile Gln Asn Leu Ser Leu Ile
                 230                 235                 240

 Ser Leu Ala Asn Leu Pro Pro Ser Gly Leu Ala Asn Ala Val Ala
                 245                 250                 255

 Glu Gly Ile Arg Ser Glu Glu Asn Ile Tyr Thr Ile Glu Glu Asn
                 260                 265                 270

 Val Tyr Glu Val Glu Glu Pro Asn Glu Tyr Tyr Cys Tyr Val Ser
                 275                 280                 285

 Ser Arg Gln Gln Pro Ser Gln Pro Leu Gly Cys Arg Phe Ala Met
                 290                 295                 300

 Pro


<210> 5966
<211> 825
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 290, 480, 491, 589, 698
<223> Unknown base

<400> 5966
 gaattcggca cgagtttttt ttttctgcag ttgtgtgtat gtgtgtttgt 50

 gtgaagaaaa acagactctg tccaggtaga aatggtgagg agggggaaga 100

 gaattacatt tccagggtca gaaacttggc aacagttttc ctakagtgac 150

 tcagacacac cacagtaaca actctcgctg caattttatt ttaatttgag 200

 aaataaagat ttcctccaag ccacatgagg actctggcac ccacccacaa 250

 agcaagacct gtatttataa gccgagggtg cagggagctn aactgcggga 300

 cccgtcaggg ccccgtggac ccatccccgt ccccaccccc ccctccaccg 350

 ytggggccca tcagtgtgtg ttggggggga tgcttgggca gctggggggt 400

 gagggagaca acaaacctyg gggaaytggg agccagagct gcggcctgac 450

 tgacgccttt tgatgctcac gggaaatttn tgcccaggat ntcagcccca 500

 ggctggttgt ttctacaaat ctctctcaaa tgtattattt tggtgacaaa 550

 aatgaaggag ctttgtaaat ttttttaaaa ttatgaatnc atatcaagta 600

 gttgtttaca tttcttgaaa aaataggaac tcgggcagca gaatcagatt 650

 ggcagaatct ttagactaca caggcaataa tcaagtctgc tgttttgncc 700

 tttcgtagta gaagtggttg tagtgtttag atatctgttt ggtcttgctt 750

 cttgtattgc atttttttca ataaacaaca acaaaaagaa aaaaaaaaaa 800

 aaaaaaaaaa aagatcttta attaa 825

<210> 5967
<211> 74
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 290, 480, 491, 589, 698
<223> Unknown amino acid

<400> 5967
 Met Arg Thr Leu Ala Pro Thr His Lys Ala Arg Pro Val Phe Ile
   1               5                  10                  15

 Ser Arg Gly Cys Arg Glu Leu Asn Cys Gly Thr Arg Gln Gly Pro
                  20                  25                  30

 Val Asp Pro Ser Pro Ser Pro Pro Pro Pro Pro Pro Leu Gly Pro
                  35                  40                  45

 Ile Ser Val Cys Trp Gly Gly Cys Leu Gly Ser Trp Gly Val Arg
                  50                  55                  60

 Glu Thr Thr Asn Leu Gly Glu Leu Gly Ala Arg Ala Ala Ala
                  65                  70

<210> 5968
<211> 1405
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 8, 35, 59
<223> Unknown base

<400> 5968
 ccctcctncc cttccttggt ccttccaacc ttaantcctt tttccaaaaa 50

 aaaaaagang aactgtgaag aacccccaaa aaacttccca cttcctggga 100

 ggccagccca caggaacagg gaacaatatt tatttgggtc tcttcagttc 150

 cccctttgag aacaacatta aatacatgtt agctggggct cccagggcat 200

 tctccttccc acagtagtgc ggccaaattc ccagtctggc cagtctcttt 250

 gttgagactg aatagaagga ctgcaggttt ttttggagga tgagataatt 300

 tttcctcgca ggcatttttc ccttgccttc cttatgcatg aatggtccct 350

 ttgaatatta tttccaaaag tgagagctaa gacaaagtca tcaaaaagag 400

 aggataacag aaggtggggg cgggggcggg gtgcagtggg gtagggttac 450

 ctgttaattg ctgagactca gatgaaagtc cagctctccc tgggcaaccc 500

 tagagggcag cagaggaccc cagagctcat tcaggccttg ctgcttgttc 550

 taaactacac cttaggattt tttcttcttt ccaaaacatt ccattgattt 600

 tataaagact ttctatagag aggctttcac ttttgagttc tttgagttta 650

 aagattgctt ttcttgaaac gctctttttt taatgtagaa aaattttact 700

 ttttcaaata tgcatacaat ttttaaaaca gtagaagcaa attcatttta 750

 atgaccatgt aaagagcgaa tgtcagacag tattattacc agtttattca 800

 aattacatac atgttcctac caaggtggaa agaaattcaa acctcatggt 850

 aaaacttaag cacgatttaa gataaaagca tagtatttct tcagtgtaga 900

 cttattaagt gccttattga acaggatctt aacctgcttt ttctgttttt 950

 ttgaaagagt taatgcaatt gttgaagctt ctaaccaaga aacaacttaa 1000

 ggaattggga gacttggtcc cctcgttgtc agggttctgg ctataagtac 1050

 ctccccacct ttgggttttc ttaaatatgc caaaaggaat tctagttttt 1100

 ataaccaatg ggtttttttg tttgtgtgct tatggatttg tgtaatcatt 1150

 gatgcttaat gttgtggatt cataatataa aaagtggctc ctgtccttta 1200

 tatttattca tgtgctagaa atagtatgca ttatataaag agtatgaagt 1250

 tttcataagc ctttatattt caagctcttt atttaaacat tgttggaata 1300

 tgtggcataa gccttgtttc atttatttaa taaactggag taatatataa 1350

 taataaaaaa aaaaaaaaaa aactcgaggg ggggcccggt acccaatcgc 1400

 cctat 1405

<210> 5969
<211> 41
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 8, 35, 59
<223> Unknown amino acid

<400> 5969
 Met Lys Val Gln Leu Ser Leu Gly Asn Pro Arg Gly Gln Gln Arg
   1               5                  10                  15

 Thr Pro Glu Leu Ile Gln Ala Leu Leu Leu Val Leu Asn Tyr Thr
                  20                  25                  30

 Leu Gly Phe Phe Leu Leu Ser Lys Thr Phe His
                  35                  40

<210> 5970
<211> 3045
<212> DNA
<213> Homo sapien

<400> 5970
 actaagaccg caaggcattc atttcctcct acggtggatg cggacgccgg 50

 gaggaggaga gccccagaga gaggagctgg gagcggaggc gcaggcaatg 100

 ctcagccctg gatgtagctg agaggctggg agaagagacg accgctggag 150

 accgagcggc gtggggaaga cctagggggg tgggtggggg aagcagacag 200

 gagaacactc gaaatcaagc gctttacaga ttattttatt ttgtatagag 250

 aacacgtagc gactccgaag atcagcccca atgaacatgt cagtgttgac 300

 tttacaagaa tatgaattcg aaaagcagtt caacgagaat gaagccatcc 350

 aatggatgca ggaaaactgg aagaaatctt tcctgttttc tgctctgtat 400

 gctgccttta tattcggtgg tcggcaccta atgaataaac gagcaaagtt 450

 tgaactgagg aagccattag tgctctggtc tctgaccctt gcagtcttca 500

 gtatattcgg tgctcttcga actggtgctt atatggtgta cattttgatg 550

 accaaaggcc tgaagcagtc agtttgtgac cagggttttt acaatggacc 600

 tgtcagcaaa ttctgggctt atgcatttgt gctaagcaaa gcacccgaac 650

 taggagatac aatattcatt attctgagga agcagaagct gatcttcctg 700

 cactggtatc accacatcac tgtgctcctg tactcttggt actcctacaa 750

 agacatggtt gccgggggag gttggttcat gactatgaac tatggcgtgc 800

 acgccgtgat gtactcttac tatgccttgc gggcggcagg tttccgagtc 850

 tcccggaagt ttgccatgtt catcaccttg tcccagatca ctcagatgct 900

 gatgggctgt gtggttaact acctggtctt ctgctggatg cagcatgacc 950

 agtgtcactc tcactttcag aacatcttct ggtcctcact catgtacctc 1000

 agctaccttg tgctcttctg ccatttcttc tttgaggcct acatcggcaa 1050

 aatgaggaaa acaacgaaag ctgaatagtg ttggaactga ggaggaagcc 1100

 atagctcagg gtcatcaaga aaaataatag acaaaagaaa atggcacaag 1150

 gaatcacacg tggtgcagct aaaacaaaac aaaacatgag caaacacaaa 1200

 acccaaggca gcttagggat aattaggttg atttaaccca gtaagtttat 1250

 gatcctttta gggtgaggac tcactgagtg cacctccatc tccaagcact 1300

 gctgctggaa gaccccattc cctctttatc tatcaactct aggacaaggg 1350

 agaacaaaag caagccagaa gcagaggaga ctaatcaaag gcaaacaaag 1400

 gctattaaca cataggaaaa tatgtattta ctaagtgtca catttctcta 1450

 agatgaaaga tttttactct agaaactgtg cgagcacaac acacacaatc 1500

 ctttctaact ttatggacac taaactggag ccaatagaaa agacaaaaat 1550

 gaaagagaca cagggtgtat atctagaacg ataatgcttt tgcagaaact 1600

 aaagcctttt taagaaatgc cagctgctgt agaccccatg agaaaagatg 1650

 tcttaatcat ccttatgaaa acagatgtaa acaactatat ttcaactaac 1700

 ttcatcttca ctgcatagcc tcaggctagt gagtttgcca aaaccaaagg 1750

 gggtgaatac ttccccaaga ttcttcctgg gaggatggaa acagtgcagc 1800

 ccaggtccca tgggggcagc tccatcccag agcatttctg atagttgaac 1850

 tgtaatttct actcttaagt gagatatgaa gtattatcct tttgttcagt 1900

 tgccccgggc ttttgaacag aagagtaaat acagaattga aaaagataaa 1950

 cactcaacca aacaatgtga aaacgggttc tgtagtattt gtaaaaaggc 2000

 ccggcccagg accactgtga gctggaaaag ggagaaaggc agtgggaaaa 2050

 gaggtgagcc gaagatcaat tcgacagaca gacggtgtgt atgcccctcc 2100

 ctgtttgact tcacacacac tcataacttt ccaaatgaaa ccccacagta 2150

 tagcgcatat tttcgatatt tttgtgaatt ccaaaaggaa atcacagggc 2200

 tgttcgaaat attgggggaa cactgtgttt ctgcatcatc tgcatttgct 2250

 ccccaagcaa tgtagaggtg tttaaagggc cctctgctgg ctgagtggca 2300

 atactacaac aaacttcaag gcaagtttgg ctgaaaacag ttgacaacaa 2350

 agggccccca tacacttatc cctcaaattt taagtgatat gaaatacttg 2400

 tcatgtcttt ggccaaatca gaagatattc atcctgcttc aagtcagctt 2450

 cagaaatgtt ttaaaaggga ctttagctct ggaactcaaa atcaatttat 2500

 taagagccat attctttaaa aaaaaaagct ggataatatt atctgtaata 2550

 tttcagtcct ttacaagcca aatacatgtg tcaatgtttc tagtatttca 2600

 aagaagcaat tatgtaaagt tgttcaatgt gacataatag tattataatt 2650

 ggttaagtag cttaatgatt aggcaaacta gatgaaaaga ttaggggctt 2700

 ccacactgca tagatcacac gcacatagcc acgcatacac acacagacac 2750

 acagatgtgg ggtacactga atttcaaagc ccaaatgaat agaaacacat 2800

 tttctggcta gcagaaaaaa acaaaacaaa actgttgttt ctctttcttg 2850

 ctttgagagt gtacagtaaa agggattttt tcgaattatt tttatattat 2900

 tttagcttta attgtgctgt cgttcatgaa acagagctgc tctgcttttc 2950

 tgtcagagat ggcaagggct ttttcagcat ctcgtttatg tgtggaattt 3000

 aaaaagaata aagttttatt ccattctgaa aaaaaaaaaa aaaaa 3045

<210> 5971
<211> 265
<212> PRT
<213> Homo sapien

<400> 5971
 Met Asn Met Ser Val Leu Thr Leu Gln Glu Tyr Glu Phe Glu Lys
   1               5                  10                  15

 Gln Phe Asn Glu Asn Glu Ala Ile Gln Trp Met Gln Glu Asn Trp
                  20                  25                  30

 Lys Lys Ser Phe Leu Phe Ser Ala Leu Tyr Ala Ala Phe Ile Phe
                  35                  40                  45

 Gly Gly Arg His Leu Met Asn Lys Arg Ala Lys Phe Glu Leu Arg
                  50                  55                  60

 Lys Pro Leu Val Leu Trp Ser Leu Thr Leu Ala Val Phe Ser Ile
                  65                  70                  75

 Phe Gly Ala Leu Arg Thr Gly Ala Tyr Met Val Tyr Ile Leu Met
                  80                  85                  90

 Thr Lys Gly Leu Lys Gln Ser Val Cys Asp Gln Gly Phe Tyr Asn
                  95                 100                 105

 Gly Pro Val Ser Lys Phe Trp Ala Tyr Ala Phe Val Leu Ser Lys
                 110                 115                 120

 Ala Pro Glu Leu Gly Asp Thr Ile Phe Ile Ile Leu Arg Lys Gln
                 125                 130                 135

 Lys Leu Ile Phe Leu His Trp Tyr His His Ile Thr Val Leu Leu
                 140                 145                 150

 Tyr Ser Trp Tyr Ser Tyr Lys Asp Met Val Ala Gly Gly Gly Trp
                 155                 160                 165

 Phe Met Thr Met Asn Tyr Gly Val His Ala Val Met Tyr Ser Tyr
                 170                 175                 180

 Tyr Ala Leu Arg Ala Ala Gly Phe Arg Val Ser Arg Lys Phe Ala
                 185                 190                 195

 Met Phe Ile Thr Leu Ser Gln Ile Thr Gln Met Leu Met Gly Cys
                 200                 205                 210

 Val Val Asn Tyr Leu Val Phe Cys Trp Met Gln His Asp Gln Cys
                 215                 220                 225

 His Ser His Phe Gln Asn Ile Phe Trp Ser Ser Leu Met Tyr Leu
                 230                 235                 240

 Ser Tyr Leu Val Leu Phe Cys His Phe Phe Phe Glu Ala Tyr Ile
                 245                 250                 255

 Gly Lys Met Arg Lys Thr Thr Lys Ala Glu
                 260                 265

<210> 5972
<211> 2343
<212> DNA
<213> Homo sapien

<400> 5972
 gctcctgcta accccatcac tgtggaaatg aaaggcctga agacagattt 50

 ggaccttcag cagtacagct ttataaatca gatgtgttat gagcgagccc 100

 tccactggta tgccaagtat ttcccttacc ttgtcctcat ccataccctg 150

 gtctttatgc tctgcagtaa cttttggttc aaattccctg gttccagctc 200

 caaaatagaa catttcatct ccattctggg gaagtgtttt gactctcctt 250

 ggaccacacg ggctttatct gaagtgtctg gggaggactc agaagaaaag 300

 gacaacagga agaacaacat gaacaggtcc aacaccatcc aatctggtcc 350

 agaaggcagc ctggtcaact ctcagtcttt aaagtccatt cctgagaagt 400

 ttgtagttga taaatccact gcaggggctc tggataaaaa ggaaggtgag 450

 caggctaagg ccttatttga gaaggtgaag aagttcaggc tgcatgtgga 500

 agaaggtgat attctatatg ccatgtatgt tcgccagact gtacttaaag 550

 ttatcaaatt cctaatcatc attgcatata atagtgctct ggtttccaag 600

 gtccagttta cagtggactg taatgtggac attcaggaca tgactggata 650

 taaaaacttt tcttgcaatc ataccatggc acacttgttc tcaaaactgt 700

 ccttttgcta tctgtgcttt gttagtatct atggattgac gtgcctttat 750

 accttatact ggctgttcta ccgttctcta cgggaatatt cctttgagta 800

 tgtccgtcag gagactggaa ttgatgatat tccagatgtg aaaaatgact 850

 ttgcttttat gcttcatatg atagatcagt atgaccctct ctattccaag 900

 agatttgcag tgttcctgtc tgaagtcagt gaaaacaaat taaagcagct 950

 gaacttaaat aacgaatgga ctcctgataa actgaggcag aagctacaga 1000

 caaatgccca taatcgactg gaattgcctc ttatcatgct ctctggcctt 1050

 ccagacactg tttttgaaat cacagagttg caatctctaa aacttgaaat 1100

 cattaagaac gtaatgatac cagccaccat tgcacagcta gacaatcttc 1150

 aagagctctc tctgcaccag tgttctgtca aaatccacag tgcggcgctc 1200

 tctttcctga aggaaaacct caaggtcttg agcgtcaagt ttgatgacat 1250

 gagggaactc cccccctgga tgtatgggct ccgaaatctg gaagagctgt 1300

 acctagttgg ctctctaagt catgatattt ccagaaatgt cacccttgag 1350

 tctctgcggg atctcaaaag ccttaaaatt ctctctatca aaagcaacgt 1400

 ttccaaaatc cctcaggcag tggttgatgt ttccagccat ctccagaaga 1450

 tgtgcataca taatgatggc accaagctgg tgatgctcaa caacttaaag 1500

 aagatgacca atctgacaga gctggagctg gtccactgtg acctggagcg 1550

 tattcctcat gctgtgttca gcctactcag cctccaggaa ttggacctga 1600

 aggaaaacaa tctgaaatct atagaagaaa tcgttagctt tcagcactta 1650

 agaaagttga cagtgctaaa actgtggcat aacagcatca cctacatccc 1700

 agagcatata aagaaactca ccagcctgga acgcctgtcc tttagtcaca 1750

 ataaaataga ggtgctgcct tcccacctct tcctatgcaa caagatccga 1800

 tacttggact tatcgtacaa tgacattcga tttatccccc ctgaaattgg 1850

 agttctacaa agtttacagt atttttccat cacatgtaac aaagtggaaa 1900

 gccttccaga tgaactctac ttctgcaaga aacttaaaac tctgaagatt 1950

 ggaaaaaaca gcctatctgt actttcaccg aaaattggaa atttgctatt 2000

 tctttcctac ttagatgtaa aaggtaatca ctttgaaatc ctccctcctg 2050

 aactgggtga ctgtcgggct ctgaagcgag ctggtttagt tgtagaagat 2100

 gctctgtttg aaactctgcc ttctgacgtc cgggagcaaa tgaaaacaga 2150

 ataacttatt tttcgttaaa gtttgactga aacacgcttc taccaaatac 2200

 agtataaata attaggtagt cttaatgcct ttcctatttt tttttccttt 2250

 tcacacaaaa tgtacacaaa gatcgcgtaa ggagtatgta tttttaataa 2300

 aaatttaatt gtattttttc aatattaaaa aaaaaaaaaa aaa 2343

<210> 5973
<211> 708
<212> PRT
<213> Homo sapien

<400> 5973
 Met Lys Gly Leu Lys Thr Asp Leu Asp Leu Gln Gln Tyr Ser Phe
   1               5                  10                  15

 Ile Asn Gln Met Cys Tyr Glu Arg Ala Leu His Trp Tyr Ala Lys
                  20                  25                  30

 Tyr Phe Pro Tyr Leu Val Leu Ile His Thr Leu Val Phe Met Leu
                  35                  40                  45

 Cys Ser Asn Phe Trp Phe Lys Phe Pro Gly Ser Ser Ser Lys Ile
                  50                  55                  60

 Glu His Phe Ile Ser Ile Leu Gly Lys Cys Phe Asp Ser Pro Trp
                  65                  70                  75

 Thr Thr Arg Ala Leu Ser Glu Val Ser Gly Glu Asp Ser Glu Glu
                  80                  85                  90

 Lys Asp Asn Arg Lys Asn Asn Met Asn Arg Ser Asn Thr Ile Gln
                  95                 100                 105

 Ser Gly Pro Glu Gly Ser Leu Val Asn Ser Gln Ser Leu Lys Ser
                 110                 115                 120

 Ile Pro Glu Lys Phe Val Val Asp Lys Ser Thr Ala Gly Ala Leu
                 125                 130                 135

 Asp Lys Lys Glu Gly Glu Gln Ala Lys Ala Leu Phe Glu Lys Val
                 140                 145                 150

 Lys Lys Phe Arg Leu His Val Glu Glu Gly Asp Ile Leu Tyr Ala
                 155                 160                 165

 Met Tyr Val Arg Gln Thr Val Leu Lys Val Ile Lys Phe Leu Ile
                 170                 175                 180

 Ile Ile Ala Tyr Asn Ser Ala Leu Val Ser Lys Val Gln Phe Thr
                 185                 190                 195

 Val Asp Cys Asn Val Asp Ile Gln Asp Met Thr Gly Tyr Lys Asn
                 200                 205                 210

 Phe Ser Cys Asn His Thr Met Ala His Leu Phe Ser Lys Leu Ser
                 215                 220                 225

 Phe Cys Tyr Leu Cys Phe Val Ser Ile Tyr Gly Leu Thr Cys Leu
                 230                 235                 240

 Tyr Thr Leu Tyr Trp Leu Phe Tyr Arg Ser Leu Arg Glu Tyr Ser
                 245                 250                 255

 Phe Glu Tyr Val Arg Gln Glu Thr Gly Ile Asp Asp Ile Pro Asp
                 260                 265                 270

 Val Lys Asn Asp Phe Ala Phe Met Leu His Met Ile Asp Gln Tyr
                 275                 280                 285

 Asp Pro Leu Tyr Ser Lys Arg Phe Ala Val Phe Leu Ser Glu Val
                 290                 295                 300

 Ser Glu Asn Lys Leu Lys Gln Leu Asn Leu Asn Asn Glu Trp Thr
                 305                 310                 315

 Pro Asp Lys Leu Arg Gln Lys Leu Gln Thr Asn Ala His Asn Arg
                 320                 325                 330

 Leu Glu Leu Pro Leu Ile Met Leu Ser Gly Leu Pro Asp Thr Val
                 335                 340                 345

 Phe Glu Ile Thr Glu Leu Gln Ser Leu Lys Leu Glu Ile Ile Lys
                 350                 355                 360

 Asn Val Met Ile Pro Ala Thr Ile Ala Gln Leu Asp Asn Leu Gln
                 365                 370                 375

 Glu Leu Ser Leu His Gln Cys Ser Val Lys Ile His Ser Ala Ala
                 380                 385                 390

 Leu Ser Phe Leu Lys Glu Asn Leu Lys Val Leu Ser Val Lys Phe
                 395                 400                 405

 Asp Asp Met Arg Glu Leu Pro Pro Trp Met Tyr Gly Leu Arg Asn
                 410                 415                 420

 Leu Glu Glu Leu Tyr Leu Val Gly Ser Leu Ser His Asp Ile Ser
                 425                 430                 435

 Arg Asn Val Thr Leu Glu Ser Leu Arg Asp Leu Lys Ser Leu Lys
                 440                 445                 450

 Ile Leu Ser Ile Lys Ser Asn Val Ser Lys Ile Pro Gln Ala Val
                 455                 460                 465

 Val Asp Val Ser Ser His Leu Gln Lys Met Cys Ile His Asn Asp
                 470                 475                 480

 Gly Thr Lys Leu Val Met Leu Asn Asn Leu Lys Lys Met Thr Asn
                 485                 490                 495

 Leu Thr Glu Leu Glu Leu Val His Cys Asp Leu Glu Arg Ile Pro
                 500                 505                 510

 His Ala Val Phe Ser Leu Leu Ser Leu Gln Glu Leu Asp Leu Lys
                 515                 520                 525

 Glu Asn Asn Leu Lys Ser Ile Glu Glu Ile Val Ser Phe Gln His
                 530                 535                 540

 Leu Arg Lys Leu Thr Val Leu Lys Leu Trp His Asn Ser Ile Thr
                 545                 550                 555

 Tyr Ile Pro Glu His Ile Lys Lys Leu Thr Ser Leu Glu Arg Leu
                 560                 565                 570

 Ser Phe Ser His Asn Lys Ile Glu Val Leu Pro Ser His Leu Phe
                 575                 580                 585

 Leu Cys Asn Lys Ile Arg Tyr Leu Asp Leu Ser Tyr Asn Asp Ile
                 590                 595                 600

 Arg Phe Ile Pro Pro Glu Ile Gly Val Leu Gln Ser Leu Gln Tyr
                 605                 610                 615

 Phe Ser Ile Thr Cys Asn Lys Val Glu Ser Leu Pro Asp Glu Leu
                 620                 625                 630

 Tyr Phe Cys Lys Lys Leu Lys Thr Leu Lys Ile Gly Lys Asn Ser
                 635                 640                 645

 Leu Ser Val Leu Ser Pro Lys Ile Gly Asn Leu Leu Phe Leu Ser
                 650                 655                 660

 Tyr Leu Asp Val Lys Gly Asn His Phe Glu Ile Leu Pro Pro Glu
                 665                 670                 675

 Leu Gly Asp Cys Arg Ala Leu Lys Arg Ala Gly Leu Val Val Glu
                 680                 685                 690

 Asp Ala Leu Phe Glu Thr Leu Pro Ser Asp Val Arg Glu Gln Met
                 695                 700                 705

 Lys Thr Glu


<210> 5974
<211> 2894
<212> DNA
<213> Homo sapien

<400> 5974
 agcactttca ttggacgagc caatcatttc ttcactgtaa ctgaccccag 50

 gaacattctg ttaaccaacg aacaactcga gagtgcgaga aaaatagtac 100

 atgattacag gcaaggaatt gttcctcctg gtcttacaga aaatgaattg 150

 tggagagcaa agtacatcta tgattcagct tttcatcctg acactggtga 200

 gaagatgatt ttgataggaa gaatgtcagc ccaggttccc atgaacatga 250

 ccatcacagg ttgtatgatg acgttttaca ggactacgcc ggctgtgctg 300

 ttctggcagt ggattaacca gtccttcaat gccgtcgtca attacaccaa 350

 cagaagtgga gacgcacccc tcactgtcaa tgagttggga acagcttacg 400

 tttctgcaac aactggtgcc gtagcaacag ctctaggact caatgcattg 450

 accaagcatg tctcaccact gataggacgt tttgttccct ttgctgccgt 500

 agctgctgct aattgcatta atattccatt aatgaggcaa agggaactca 550

 aagttggcat tcccgtcacg gatgagaatg ggaaccgctt gggggagtcg 600

 gcgaacgctg cgaaacaagc catcacgcaa gttgtcgtgt ccaggattct 650

 catggcagcc cctggcatgg ccatccctcc attcattatg aacactttgg 700

 aaaagaaagc ctttttgaag aggttcccat ggatgagtgc acccattcaa 750

 gttgggttag ttggcttctg tttggtgttt gctacacccc tgtgttgtgc 800

 cctgtttcct cagaaaagtt ccatgtctgt gacaagcttg gaggccgagt 850

 tgcaagctaa gatccaagag agccatcctg aattgcgacg cgtgtacttc 900

 aataagggat tgtaaagcag ggaggaaacc tctgcagctc attctgccac 950

 tgcaaagctg gtgtagccat gctggtgaga aaaatcctgt tcaacctggg 1000

 ttctcccagt tacggaaacc ttttaaagat ccacattagc cttttagaat 1050

 aaagctgcta ctttaacaga gcacctggcg tgggccaagt gcctgatact 1100

 cccttacact gaatcatgtt atgatttata gaaatacctt tcctgtagct 1150

 tttatagtca ttgtttttca aagacgatat accagccctc acccaggttt 1200

 taaaaaagca ctggtaggca tagaataggt gctcagtata tggtcagtaa 1250

 atgttctatt gattatcaat cagtgaaaaa agaaatctgt ttaaaatact 1300

 gaattttcat ctcactccca ttgcaaatca aggagatctc agcagtgaac 1350

 tgggaaaata caaaagctct gggctaatct ataaaaactt accctgaaat 1400

 attaagggca gtttgcttct agtttgggga ttgcgctagc ccaatgaagg 1450

 tgatgaagct tttggatttg gagggtaaaa gctccttcac accccttcca 1500

 aaagtcagtc acagaccact gcaacatgcc ttccctgctg gatcattata 1550

 tacattcaga ttgtgagtgg attgccttgg ttgactttta atttattgtt 1600

 ttttgttctt ataaagatga taatcttacc ttgcagttat tgactttata 1650

 ttcaattatt tacatcaaat aatgaaataa ctgaaatgta caaatgtcaa 1700

 attttggaag tatattcaat accaatgctg tatgagtggg ctgaatccag 1750

 ttcattgttt tttttttggt aagaagtgag actacagttc cagctaccta 1800

 catgtctttt cttgtcatcc ttatagatct ctttggcttt cagaaagata 1850

 cagtgataat gtgtgtatga atcagtcaca atgaatttta cttgaatatt 1900

 gtatgttgca ttccacttca tttgaaaata atgaaaccat gtaccactgt 1950

 ttacatcatc tgtagtgatt tcatagataa tatatttaat atgacagatt 2000

 atgtttcaac tctgtagatg tttaacgtca tagacagttg gccctctgta 2050

 tccgtgagct ctatatctgt gaattcaacc aagtttggat ggaaaatttt 2100

 tttttttttt ttttttttga gacggagtct cgctctgtca cccaggctgg 2150

 agtgcagtgg cgtagtctcg gctcactgca agctccgcct cctgggttca 2200

 cgccgttctc ctgcctcagc ctctctgaga agctgggact acaggcgccc 2250

 gccaccacgc ccggctaatt tttttgtatt tttagtagag acggggtttc 2300

 actgtggtct cgatctcctg acctcgtgat ccgcccgcct tggcctccca 2350

 aggtgctggg attacaagcg tgagccaccg cacccggcct gaaaatattt 2400

 tctaaaaaga taaaaaatat acataacgat gaaaaataat acaaatttaa 2450

 aaaccaatac agtataacaa ctatttacat agtgcttaca ttgtattagg 2500

 tgttataagc aatctagaga tgatttagca agtatacagg aggatgtgcc 2550

 taggttatat gcaaatactg tgccatttta tatcaggaac ttgagcatct 2600

 gcagatattg gtatcggagg gcggtcctgg aaccaagcat ccacggatac 2650

 tgaggggtga catttcatga agtgtagatc attgtattca gagattgtaa 2700

 atgaaaaaaa tatagaaact atttagtttt ggtagatttt ttttctgaca 2750

 atgtgaccag actgaatttc ctcataaaga aaaaatggcg tgccttgtgt 2800

 ctgtgtttct cttttctctg aaaggattaa tagatctgaa gctttgggcc 2850

 acttagagcc ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 2894

<210> 5975
<211> 236
<212> PRT
<213> Homo sapien

<400> 5975
 Met Ile Leu Ile Gly Arg Met Ser Ala Gln Val Pro Met Asn Met
   1               5                  10                  15

 Thr Ile Thr Gly Cys Met Met Thr Phe Tyr Arg Thr Thr Pro Ala
                  20                  25                  30

 Val Leu Phe Trp Gln Trp Ile Asn Gln Ser Phe Asn Ala Val Val
                  35                  40                  45

 Asn Tyr Thr Asn Arg Ser Gly Asp Ala Pro Leu Thr Val Asn Glu
                  50                  55                  60

 Leu Gly Thr Ala Tyr Val Ser Ala Thr Thr Gly Ala Val Ala Thr
                  65                  70                  75

 Ala Leu Gly Leu Asn Ala Leu Thr Lys His Val Ser Pro Leu Ile
                  80                  85                  90

 Gly Arg Phe Val Pro Phe Ala Ala Val Ala Ala Ala Asn Cys Ile
                  95                 100                 105

 Asn Ile Pro Leu Met Arg Gln Arg Glu Leu Lys Val Gly Ile Pro
                 110                 115                 120

 Val Thr Asp Glu Asn Gly Asn Arg Leu Gly Glu Ser Ala Asn Ala
                 125                 130                 135

 Ala Lys Gln Ala Ile Thr Gln Val Val Val Ser Arg Ile Leu Met
                 140                 145                 150

 Ala Ala Pro Gly Met Ala Ile Pro Pro Phe Ile Met Asn Thr Leu
                 155                 160                 165

 Glu Lys Lys Ala Phe Leu Lys Arg Phe Pro Trp Met Ser Ala Pro
                 170                 175                 180

 Ile Gln Val Gly Leu Val Gly Phe Cys Leu Val Phe Ala Thr Pro
                 185                 190                 195

 Leu Cys Cys Ala Leu Phe Pro Gln Lys Ser Ser Met Ser Val Thr
                 200                 205                 210

 Ser Leu Glu Ala Glu Leu Gln Ala Lys Ile Gln Glu Ser His Pro
                 215                 220                 225

 Glu Leu Arg Arg Val Tyr Phe Asn Lys Gly Leu
                 230                 235

<210> 5976
<211> 3049
<212> DNA
<213> Homo sapien

<400> 5976
 ttgctcggcg tttattagtg ctgtctgggt agcattccca ttgctcacaa 50

 agctctgtgt gcataaggac ttcaagcagc atggtgccca aggaaaattt 100

 attgcttttt accttttggg gatgtttatt ccttatcttt atgcattgta 150

 cctcatctgg gcagtatttg agatgtttac ccctatcctc gggagaagtg 200

 gttctgaaat cccacctgat gttgtgctgg catccatttt ggctggctgt 250

 acaatgattc tctcgtccta ttttattaac ttcatctacc ttgccaagag 300

 cacaaaaaaa accatgctaa ctttaacttt ggtatgtgca attacattcc 350

 tccttgtttg cagtggaaca ttttttccat atagctccaa tcctgctaat 400

 ccgaagccaa agagagtgtt tcttcagcat atgactagaa cattccatga 450

 cttggaagga aatgcagtta aacgggactc tggaatatgg atcaatgggt 500

 ttgattatac tggaatttct cacataaccc ctcacattcc tgcgatcaat 550

 gatagtatcc gagctcactg tgaggagaat gcacctcttt gtggttttcc 600

 ttggtatctt ccagtgcact ttctgatcag gaaaaactgg tatcttcctg 650

 ccccagaagt ttctccaaga aatcctcctc atttccgact catatccaaa 700

 gaacagacac cttgggattc tataaaattg acttttgaag caacaggacc 750

 aagccatatg tccttctatg ttcgagccca caaagggtca acactttctc 800

 agtggtctct tggcaatggc accccagtca caagtaaagg aggagactac 850

 tttgtctttt actcccatgg actccaggcc tctgcatggc agttctggat 900

 agaagtgcag gtttcagaag aacatcctga aggaatggtc accgtggcca 950

 ttgctgccca ctatctgtct ggggaagaca agagatcccc tcaactggat 1000

 gctctgaagg aaaagttccc agattggaca tttccctctg cctgggtgtg 1050

 cacctacgat ctctttgtat tttaatcttg tggatgagct ctaagtacat 1100

 gcccagtgga tactccatgt gacatggttt ctccctatgt tacgtggatg 1150

 tttgtaacgt aagtcaatga attttaatga tcatatgttc aaagagcttt 1200

 ctgggttaac gcttttcagg gccaagcact ataagggttt agctgtggcg 1250

 cagtgatgca tggcctgttg acacttgaaa atgccagtct tttggcactt 1300

 cagcacatgt gggtactgcc actacacaca cgtcatttta tatgacctta 1350

 aggacaaagc caacaatcca cttcaatagc tgccccttta ggatcaagaa 1400

 agatgtacac tgtcagagca ttgttaatga gacaaaagtt gtttccaatt 1450

 taagccccaa aaccatttgt tgtattagtg gatggtgggt aaaatatcat 1500

 tcactgaggt aatgattccc cttgagaata taactctgtg taggtcactg 1550

 gaaagtgatt gccatagggc tgggagagaa gcattgcact cttgaggctg 1600

 tagcctgtgt caagctgttt cttcaggcag cctctcaaat gtgctttgtc 1650

 tctctgtgct gaggcctgga ccctgtgctg agctggtgac tcactgtcct 1700

 gacaagtgga cacacagatg cactgctgtg ctgctttcct gaggtggttt 1750

 tctatgcctg ttttcctctg aaacatgtct gttacccctc tccatcttac 1800

 caagttgaaa aggggaatat ttggccacat acccctctgg ttttcgtagg 1850

 ttcttttggt tcagaatatt gtttgtgcca gtacatgacc ttaacttcct 1900

 tcctcagagc actgagctgc catctgggct attccggggt agaaggaagg 1950

 ctgggagtgg tgggaatttt ataaatattt attctctttt ctttgtttca 2000

 taggagtctt gtgttataca aggttagtcc ttcatggtat aatcttactg 2050

 atgcactggg cctatctttt tgttttccag ccagttgaat agattagttt 2100

 ttctcagtaa cttactatcc agcagactgg ctttcctgag acttgaggtt 2150

 gtggcttgta ctggaatgag accactgtac gtgtaggtgg ttcagatcct 2200

 gcgtaatggc agcatgagga cttaaaaggt ggttttcatt ttgaagatgg 2250

 ctatgtagct tgtaaggtgt atcacagcag tacctctcat ggctttttgg 2300

 ttccagcagt gagggcattg gtgagatcaa tggtaaactg tgcaagcttt 2350

 ctttttatca ttaggaaatg tgaaacgttg gacaaatttt gagttttaac 2400

 aaggacaaaa agttgaaaga aaaggcacag ttaacaaaaa agggtggcta 2450

 gatttatctt gggtgatgga ggaaatgaga gaggaatgct cttgaaaggt 2500

 ggtctgtgga tctgtctgaa tagaaagagc acagtaagta tgcattgccg 2550

 gagaaaacgt ccttgaagct gcttgtctca tgtgtatgat gtgcttttta 2600

 aatcatgccc ctcgttgcct gcctaatctg tgactcccta aaaactaact 2650

 gggcccatgt agatggggct gcaaccagag ctgaataaca tgttaggctc 2700

 acacatgcat cagcactgca cactgaaatc attgctcttc ctggactttg 2750

 tagaaatcag tctcaagtgc ttcaagagtc tggctcctgc tacttttatc 2800

 tgtcaggtag cacataaggt ttgcagggtt tatattttgt atagaatcac 2850

 agttgtggag aaaaagtaat aatttctcaa tgaattttaa aaatgggcct 2900

 attttctatc cccgtggttc atctgatata attagtgttc cctgtgaatt 2950

 ccccccctct atgggaagga tgcctttact ctttatcagt aataaattat 3000

 gactgttttc atattgcctt agggttaaaa aaaaaaaaaa aaaaaaaaa 3049

<210> 5977
<211> 317
<212> PRT
<213> Homo sapien

<400> 5977
 Met Phe Ile Pro Tyr Leu Tyr Ala Leu Tyr Leu Ile Trp Ala Val
   1               5                  10                  15

 Phe Glu Met Phe Thr Pro Ile Leu Gly Arg Ser Gly Ser Glu Ile
                  20                  25                  30

 Pro Pro Asp Val Val Leu Ala Ser Ile Leu Ala Gly Cys Thr Met
                  35                  40                  45

 Ile Leu Ser Ser Tyr Phe Ile Asn Phe Ile Tyr Leu Ala Lys Ser
                  50                  55                  60

 Thr Lys Lys Thr Met Leu Thr Leu Thr Leu Val Cys Ala Ile Thr
                  65                  70                  75

 Phe Leu Leu Val Cys Ser Gly Thr Phe Phe Pro Tyr Ser Ser Asn
                  80                  85                  90

 Pro Ala Asn Pro Lys Pro Lys Arg Val Phe Leu Gln His Met Thr
                  95                 100                 105

 Arg Thr Phe His Asp Leu Glu Gly Asn Ala Val Lys Arg Asp Ser
                 110                 115                 120

 Gly Ile Trp Ile Asn Gly Phe Asp Tyr Thr Gly Ile Ser His Ile
                 125                 130                 135

 Thr Pro His Ile Pro Ala Ile Asn Asp Ser Ile Arg Ala His Cys
                 140                 145                 150

 Glu Glu Asn Ala Pro Leu Cys Gly Phe Pro Trp Tyr Leu Pro Val
                 155                 160                 165

 His Phe Leu Ile Arg Lys Asn Trp Tyr Leu Pro Ala Pro Glu Val
                 170                 175                 180

 Ser Pro Arg Asn Pro Pro His Phe Arg Leu Ile Ser Lys Glu Gln
                 185                 190                 195

 Thr Pro Trp Asp Ser Ile Lys Leu Thr Phe Glu Ala Thr Gly Pro
                 200                 205                 210

 Ser His Met Ser Phe Tyr Val Arg Ala His Lys Gly Ser Thr Leu
                 215                 220                 225

 Ser Gln Trp Ser Leu Gly Asn Gly Thr Pro Val Thr Ser Lys Gly
                 230                 235                 240

 Gly Asp Tyr Phe Val Phe Tyr Ser His Gly Leu Gln Ala Ser Ala
                 245                 250                 255

 Trp Gln Phe Trp Ile Glu Val Gln Val Ser Glu Glu His Pro Glu
                 260                 265                 270

 Gly Met Val Thr Val Ala Ile Ala Ala His Tyr Leu Ser Gly Glu
                 275                 280                 285

 Asp Lys Arg Ser Pro Gln Leu Asp Ala Leu Lys Glu Lys Phe Pro
                 290                 295                 300

 Asp Trp Thr Phe Pro Ser Ala Trp Val Cys Thr Tyr Asp Leu Phe
                 305                 310                 315

 Val Phe


<210> 5978
<211> 1445
<212> DNA
<213> Homo sapien

<400> 5978
 gttgggcgag atgaagctac actgtgaggt ggaggtgatc agccggcact 50

 tgcccgcctt ggggcttagg aaccggggca aggtcgtccg atccgtgttg 100

 agcctctgtc agcagacttc caggagtcag ccgccggtcc gagccttcct 150

 gctcatctcc accctgaagg acaagcgcgg gacccgctat gagctaaggg 200

 agaacattga gcaattcttc accaaatttg tagatgaggg gaaagccact 250

 gttcggttaa aggagcctcc tgtggatatc tgtctaagta aggccatttc 300

 cagcagttta aaaggtttcc tttcagctat gagactggct catagaggct 350

 gtaatgttga tacaccagtt tcaacgctca caccagtgaa gacttcagaa 400

 tttgaaaact ttaaaactaa aatggttatc acatccaaaa aagactatcc 450

 tctaagtaag aattttccat attccttgga acatcttcag acttcttact 500

 gtgggcttgt ccgagttgat atgcgtatgc tttgcttaaa aagccttagg 550

 aaattagact tgagtcacaa ccatataaaa aagcttccag ctacaattgg 600

 agacctcata caccttcaag aacttaacct gaatgacaat cacttggagt 650

 catttagtgt agccttgtgt cattctacgc tccagaagtc acttcggagt 700

 ttggacctca gcaagaacaa aatcaaggca ctccctgtgc agttttgcca 750

 gctccaggaa cttaagaatt taaaacttga cgataatgaa ttgattcaat 800

 ttccttgcaa gataggacaa ctaataaacc ttcgcttttt gtcagcagct 850

 cgaaataagc ttccattttt gcctagtgaa tttagaaatt tatcccttga 900

 atacttggat ctttttggaa atacttttga acaaccaaaa gtccttccag 950

 taataaagct gcaagcacca ttaactttat tggaatcttc tgcacgaacc 1000

 atattacata ataggatccc atatggctct catatcattc cattccatct 1050

 ctgccaagat ttggataccg caaaaatttg tgtttgtgga agattctgtc 1100

 tgaactcttt cattcaagga actactacca tgaatctgca ttctgttgcc 1150

 cacactgtgg tcttagtaga taatttgggt ggtactgaag cacctattat 1200

 ctcttatttc tgttctctag gctgttatgt taattcctct gatatgttaa 1250

 agtaatgggt gagaccagaa aaagaaattt caataacaga tcagtttggg 1300

 gtgcatgtat gattttgcag cgtcaaattg gagtaaggga agatttctgt 1350

 atacttgctg gagaggagga atgtgtatag ttactcattt agatgactcc 1400

 aaacttttat taaaaccaat tttagtttta aaaaaaaaaa aaaaa 1445

<210> 5979
<211> 414
<212> PRT
<213> Homo sapien

<400> 5979
 Met Lys Leu His Cys Glu Val Glu Val Ile Ser Arg His Leu Pro
   1               5                  10                  15

 Ala Leu Gly Leu Arg Asn Arg Gly Lys Val Val Arg Ser Val Leu
                  20                  25                  30

 Ser Leu Cys Gln Gln Thr Ser Arg Ser Gln Pro Pro Val Arg Ala
                  35                  40                  45

 Phe Leu Leu Ile Ser Thr Leu Lys Asp Lys Arg Gly Thr Arg Tyr
                  50                  55                  60

 Glu Leu Arg Glu Asn Ile Glu Gln Phe Phe Thr Lys Phe Val Asp
                  65                  70                  75

 Glu Gly Lys Ala Thr Val Arg Leu Lys Glu Pro Pro Val Asp Ile
                  80                  85                  90

 Cys Leu Ser Lys Ala Ile Ser Ser Ser Leu Lys Gly Phe Leu Ser
                  95                 100                 105

 Ala Met Arg Leu Ala His Arg Gly Cys Asn Val Asp Thr Pro Val
                 110                 115                 120

 Ser Thr Leu Thr Pro Val Lys Thr Ser Glu Phe Glu Asn Phe Lys
                 125                 130                 135

 Thr Lys Met Val Ile Thr Ser Lys Lys Asp Tyr Pro Leu Ser Lys
                 140                 145                 150

 Asn Phe Pro Tyr Ser Leu Glu His Leu Gln Thr Ser Tyr Cys Gly
                 155                 160                 165

 Leu Val Arg Val Asp Met Arg Met Leu Cys Leu Lys Ser Leu Arg
                 170                 175                 180

 Lys Leu Asp Leu Ser His Asn His Ile Lys Lys Leu Pro Ala Thr
                 185                 190                 195

 Ile Gly Asp Leu Ile His Leu Gln Glu Leu Asn Leu Asn Asp Asn
                 200                 205                 210

 His Leu Glu Ser Phe Ser Val Ala Leu Cys His Ser Thr Leu Gln
                 215                 220                 225

 Lys Ser Leu Arg Ser Leu Asp Leu Ser Lys Asn Lys Ile Lys Ala
                 230                 235                 240

 Leu Pro Val Gln Phe Cys Gln Leu Gln Glu Leu Lys Asn Leu Lys
                 245                 250                 255

 Leu Asp Asp Asn Glu Leu Ile Gln Phe Pro Cys Lys Ile Gly Gln
                 260                 265                 270

 Leu Ile Asn Leu Arg Phe Leu Ser Ala Ala Arg Asn Lys Leu Pro
                 275                 280                 285

 Phe Leu Pro Ser Glu Phe Arg Asn Leu Ser Leu Glu Tyr Leu Asp
                 290                 295                 300

 Leu Phe Gly Asn Thr Phe Glu Gln Pro Lys Val Leu Pro Val Ile
                 305                 310                 315

 Lys Leu Gln Ala Pro Leu Thr Leu Leu Glu Ser Ser Ala Arg Thr
                 320                 325                 330

 Ile Leu His Asn Arg Ile Pro Tyr Gly Ser His Ile Ile Pro Phe
                 335                 340                 345

 His Leu Cys Gln Asp Leu Asp Thr Ala Lys Ile Cys Val Cys Gly
                 350                 355                 360

 Arg Phe Cys Leu Asn Ser Phe Ile Gln Gly Thr Thr Thr Met Asn
                 365                 370                 375

 Leu His Ser Val Ala His Thr Val Val Leu Val Asp Asn Leu Gly
                 380                 385                 390

 Gly Thr Glu Ala Pro Ile Ile Ser Tyr Phe Cys Ser Leu Gly Cys
                 395                 400                 405

 Tyr Val Asn Ser Ser Asp Met Leu Lys
                 410

<210> 5980
<211> 1170
<212> DNA
<213> Homo sapien

<400> 5980
 ggcggtacag acacttttaa ctcacagtaa aagcaaaagc aacagctcaa 50

 gcagcctcct tggagaaaac ctgaaaattc aacttgttca agagaaggtc 100

 ttgtacgtgc ctaagttcta gagcctcctg acgtgagcat ggctgagagt 150

 gaggaccgct ccctgaggat cgttctggta gggaaaactg gaagtgggaa 200

 aagtgcaaca gcgaacacca tccttggaga ggaaatcttt gattctagaa 250

 ttgctgccca agctgttacc aagaactgtc aaaaagcatc ccgggaatgg 300

 caggggagag accttcttgt tgtggacact ccagggctct ttgacaccaa 350

 ggagagcctg gacaccacct gcaaggaaat cagccgctgc atcatctcct 400

 cctgcccagg gccccatgct attgtcctag ttctgctgct gggccgctac 450

 acagaggagg agcagaaaac cgttgcattg atcaaggctg tctttgggaa 500

 gtcagccatg aagcacatgg tcatcttgtt cactcgcaaa gaagagttgg 550

 agggccagag cttccatgac ttcatagcag atgcggatgt gggcctaaaa 600

 agcatcgtca aggagtgcgg gaaccgctgc tgtgccttta gcaacagcaa 650

 gaaaaccagt aaggcagaga aggaaagtca agtgcaggag ttggtggagc 700

 tgatagagaa aatggtgcag tgcaacgaag gggcttactt ttctgatgac 750

 atatacaagg acacagagga aaggctgaaa caacgggaag aggttttgag 800

 gaaaatctac actgaccaat taaatgaaga aattaaacta gtagaagagg 850

 ataagcataa atcagaggaa gaaaaggaga aagaaattaa attactaaaa 900

 ttaaaatatg atgaaaaaat aaaaaatata agggaagaag ctgagagaaa 950

 tatatttaaa gatgttttta ataggatttg gaagatgctt tcagaaatat 1000

 ggcataggtt tttgtcgaaa tgtaagtttt attcttccta atttactgtg 1050

 atttgttaat ggatgaattg tattttgcaa agatagagaa atacctcctt 1100

 ccccttagct ttattaaggt atcattgata aataaaaata aaatatgttt 1150

 aatgtatata atgtgattct 1170

<210> 5981
<211> 346
<212> PRT
<213> Homo sapien

<400> 5981
 Ala Val Gln Thr Leu Leu Thr His Ser Lys Ser Lys Ser Asn Ser
   1               5                  10                  15

 Ser Ser Ser Leu Leu Gly Glu Asn Leu Lys Ile Gln Leu Val Gln
                  20                  25                  30

 Glu Lys Val Leu Tyr Val Pro Lys Val Leu Glu Pro Pro Asp Val
                  35                  40                  45

 Ser Met Ala Glu Ser Glu Asp Arg Ser Leu Arg Ile Val Leu Val
                  50                  55                  60

 Gly Lys Thr Gly Ser Gly Lys Ser Ala Thr Ala Asn Thr Ile Leu
                  65                  70                  75

 Gly Glu Glu Ile Phe Asp Ser Arg Ile Ala Ala Gln Ala Val Thr
                  80                  85                  90

 Lys Asn Cys Gln Lys Ala Ser Arg Glu Trp Gln Gly Arg Asp Leu
                  95                 100                 105

 Leu Val Val Asp Thr Pro Gly Leu Phe Asp Thr Lys Glu Ser Leu
                 110                 115                 120

 Asp Thr Thr Cys Lys Glu Ile Ser Arg Cys Ile Ile Ser Ser Cys
                 125                 130                 135

 Pro Gly Pro His Ala Ile Val Leu Val Leu Leu Leu Gly Arg Tyr
                 140                 145                 150

 Thr Glu Glu Glu Gln Lys Thr Val Ala Leu Ile Lys Ala Val Phe
                 155                 160                 165

 Gly Lys Ser Ala Met Lys His Met Val Ile Leu Phe Thr Arg Lys
                 170                 175                 180

 Glu Glu Leu Glu Gly Gln Ser Phe His Asp Phe Ile Ala Asp Ala
                 185                 190                 195

 Asp Val Gly Leu Lys Ser Ile Val Lys Glu Cys Gly Asn Arg Cys
                 200                 205                 210

 Cys Ala Phe Ser Asn Ser Lys Lys Thr Ser Lys Ala Glu Lys Glu
                 215                 220                 225

 Ser Gln Val Gln Glu Leu Val Glu Leu Ile Glu Lys Met Val Gln
                 230                 235                 240

 Cys Asn Glu Gly Ala Tyr Phe Ser Asp Asp Ile Tyr Lys Asp Thr
                 245                 250                 255

 Glu Glu Arg Leu Lys Gln Arg Glu Glu Val Leu Arg Lys Ile Tyr
                 260                 265                 270

 Thr Asp Gln Leu Asn Glu Glu Ile Lys Leu Val Glu Glu Asp Lys
                 275                 280                 285

 His Lys Ser Glu Glu Glu Lys Glu Lys Glu Ile Lys Leu Leu Lys
                 290                 295                 300

 Leu Lys Tyr Asp Glu Lys Ile Lys Asn Ile Arg Glu Glu Ala Glu
                 305                 310                 315

 Arg Asn Ile Phe Lys Asp Val Phe Asn Arg Ile Trp Lys Met Leu
                 320                 325                 330

 Ser Glu Ile Trp His Arg Phe Leu Ser Lys Cys Lys Phe Tyr Ser
                 335                 340                 345

 Ser


<210> 5982
<211> 721
<212> DNA
<213> Homo sapien

<400> 5982
 atgaaggctg aggtgtgcgc cttttttttt tttccttctt agtcgtgtgt 50

 acatcattgg gaatggaggg aaataaatga ctggatggtc gctgcttttt 100

 aagtttcaaa ttgacattcc agacaagcgg tgcctgagcc cgtgcctgtc 150

 ttcagatctt cacagcacag ttcctgggaa gggtggagcc accagcctct 200

 ccctgaataa ctgggagatg aaacaggaag ctctatgaca cacttgatcg 250

 aatatgacag acactgaaaa tcacgactca tccccctcca gcacctctac 300

 ctgttgcccg ccgatcacag ccggaatgca gctgaaagat tccctggggc 350

 ctggttccaa ccgcccactg tggactctga ggcctctgca tttgcgggtg 400

 gtctgcctgt gatattttgg tcatgggctg gtctggtcgg tttcccattt 450

 gtctggccag tctctgtgtg tcttaatccc ttgtccttca ttaaaagcaa 500

 aactaatgaa acaataatca tatcctctcc tcttcgctct ctctacccct 550

 ctccctctac acctctaact ccctcccctt ctacccaaca atttcggccc 600

 gcttggccca gcccattttt acctctgcca ggtttatcaa tgcgctccga 650

 attcgggtcc acttggccca attccccctt aagggggccc gtttactcca 700

 tggcccgcgt tttcgcgtcc g 721

<210> 5983
<211> 26
<212> PRT
<213> Homo sapien

<400> 5983
 Met Arg Ser Glu Phe Gly Ser Thr Trp Pro Asn Ser Pro Leu Arg
   1               5                  10                  15

 Gly Pro Val Tyr Ser Met Ala Arg Val Phe Ala
                  20                  25

<210> 5984
<211> 2721
<212> DNA
<213> Homo sapien

<400> 5984
 ggggatttga gggtcattgg ttctgagggc cctccgcctg ctcttttgct 50

 tctaaatcca gcatcttctg tatgaccttt gtcccgctcc tgccacccca 100

 cgaagacaga cgtgagggtc aggggagccg cggtgctaac tgccactctg 150

 ggcgggcaca ggcgagggct gtgcagcacc cgggcacgtg gggtcttcgg 200

 aggggctgct ccccacacca cttcccctgc ccctgccgag ccctgccgtg 250

 gggtgggggg cgcagggaga gaaagcagct gccctgggtg agagccagga 300

 gggacactgg gcaggcagat gccaccccag gtgtggggac ccccgctact 350

 gagtggccgg gaggagccca caggctcccc acatgcagct gagcccaggg 400

 ttgtggtcgt gggtcgtggg tcaaggatgg tggctgctgt ggttggggga 450

 gaggctcaag gcccgcctgc caaccttgtc acctatgtgg gggtgagggg 500

 agcccgccag aggccagagc ccccactgtc ccttcccacc ctccagccag 550

 gctccaggcc tcctagggcc agagtatctg agccttctct cgcttgccgg 600

 gcctgtggtt tgggggtttg tgtggagcct ggtccaggag ccctccttcc 650

 tgatctgcac tggctggccc tcctgacagc cccaggcccc cgtgccctct 700

 gccaggaggt gccttgccac ttggcatggc ccgtcacggg tggcacatct 750

 ggggtgaatg cacgtcagtg gaggcagaat cattctgtct gaatgaatgg 800

 agtttccagg cccccactgg ccctctgtgt gagggtctgc agggtttggc 850

 aggacaggtc tttctctccg gcgagagcac ccaccctgac cggctgctgg 900

 atgagggcac caaagctcgc tagggagggc tctgtcctta gggaggagct 950

 gcggaatccc tgcagctgtg cccccaggcc ctgccttgca cacttcctgc 1000

 agccagggcg cccctgggga ggtcagggca ggccggggag gctgaggccc 1050

 acctgccata gtgggcaggt gcgggagcca gggcggcagt ggcctcgggg 1100

 ctgggtgggg cgcctggcct ctggtctctg gagcagtcag gggctctgca 1150

 gacgctgaga ggcctgctca tagtggactg ggagatgctg gagcagcctc 1200

 agagccatgg ccggcccacg gcgggagacg gccctgctgc tgcccctctg 1250

 cctgtgcgtg tgcacctgtg ggcacctgcg tgtgctgggg caggcagggc 1300

 tgtattggga ccaggtcccg taacagcctg cctgcttacc gtctgctccc 1350

 atccctgggg aaagcaaggg agctcggggt cctaggacct gacctcagcg 1400

 ctcaccccca ccagcaccac agtcaccagg actctgtgac tcagtttacc 1450

 ccacgagagc ccctgggatt cccagggcat cagaaggccc atcagcctcc 1500

 cgtgaactgc tggggtgggc ctggccttgg gacgcgggtg caggggcctc 1550

 tcctcactgc ccccatggca cccacagcca gtgcccgagc ctgctgcagc 1600

 cccgacccgg cagagcaagc ggctctgcta cctcagccac gtagctgatg 1650

 gcatccttca ggttcagctc gtggaagaca ttcaggatcc ggtctcgaga 1700

 cttctgggcc gaccgtctca tgaggaccct gctgaggaac ttcctgtcga 1750

 agtgggacca cctgtaggga cagaccttgg gtgtgagcct caggtgacag 1800

 gcgccctaga gcccgccgga cgcgtggccc ggccccttct ctcctgaatt 1850

 ttgtttgcta tagtgaccct gtaggcgcgt ttaaaatgag ggaagcagcc 1900

 cctgccacac gcccaggccg tccgccgttc tcccgcctgt cctgttggat 1950

 ggaggccgtt agacgcatat gaaactgcat gccgcctcct ccagagggtg 2000

 gctcaggaca cggtgggtgt caggcctggt caggcaaggg ggctttggcc 2050

 acatgggggg gcaccttcag gtgcacagga ggaagggcag gggcggacag 2100

 acaccctgag cccttagact tgtgggagcc aagctgacca gagtgaggtt 2150

 ttttttagcc taacggaatt agagtattcg ctggttatcc ggatcagaag 2200

 ggacggtggc ctggccggac ttagaggaaa ctctggggca caaggaggtg 2250

 atgcctgtca cttggacatg ggtgcagccg ccagagccgc cctccagggc 2300

 acagggtggg cccgggtgag cttgtgtgct cacacctggg caggccccgc 2350

 ggcagcaatg gcagctctcc tgtacaggct gagtttcagc cacaccaaga 2400

 agtcaaagct aaccgaggct gtgccttccg agacccccgg gatggcccct 2450

 gggaggccaa ggagtcgggg actgggtacc cggagcagag tcactgtggc 2500

 cacggagaac cgcagctgag ctttatgaag ccacgtggcc acacctcccg 2550

 gtgcctccac cccaagcaaa cacagatcgc tcagaaaatg ggaacccagg 2600

 gcaaattgta tgtgctcctt actgggttta ttataagtgt cacatgtttt 2650

 ttataataaa acataggtga tttcacctta atggaaaaaa aaaaaaaaaa 2700

 aaaaaaaaaa aaaaaaaaaa a 2721

<210> 5985
<211> 2147
<212> DNA
<213> Homo sapien

<400> 5985
 tgagagctcc aggcgcacat ccgcagtcag ccacgtcgcg cgcgcctcca 50

 ggagcaagga tggagaggct ggtgatcagg atgcccttct gtcatctgtc 100

 tacctacagc ctggtttggg tcatggcagc agtggtgctg tgcacagcac 150

 aagtgcaagt ggtgacccag gatgaaagag agcagctgta cacacctgct 200

 tccttaaaat gctctctgca aaatgcccag gaagccctca ttgtgacatg 250

 gcagaaaaag aaagctgtaa gcccagaaaa catggtcacc ttcagcgaga 300

 accatggggt ggtgatccag cctgcctata aggacaagat aaacattacc 350

 cagctgggac tccaaaactc aaccatcacc ttctggaata tcaccctgga 400

 ggatgaaggg tgttacatgt gtctcttcaa tacctttggt tttgggaaga 450

 tctcaggaac ggcctgcctc accgtctatg tacagcccat agtatccctt 500

 cactacaaat tctctgaaga ccacctaaat atcacttgct ctgccactgc 550

 ccgcccagcc cccatggtct tctggaaggt ccctcggtca gggattgaaa 600

 atagtacagt gactctgtct cacccaaatg ggaccacgtc tgttaccagc 650

 atcctccata tcaaagaccc taagaatcag gtggggaagg aggtgatctg 700

 ccaggtgctg cacctgggga ctgtgaccga ctttaagcaa accgtcaaca 750

 aaggctattg gttttcagtt ccgctattgc taagcattgt ttccctggta 800

 attcttctcg tcctaatctc aatcttactg tactggaaac gtcaccggaa 850

 tcaggaccga gagccctaaa taagtcacac agcaccctga aagtgattcc 900

 ctggtctact tgaatttgac acaagagaaa agcaggagga aaaggggcca 950

 ttctccaaag gacctgaaag agcaaaagag gtgggagcga aagccttaag 1000

 gatcccacga ctttttactg ccatctgagc tactcagtgt ttgaatccca 1050

 agaggaagtc agtttacctc tcaggtctgt tgtaggactt gattttgtaa 1100

 agcaatgcca tgttatgtgg ttgaaagggc actggactta gttagtatca 1150

 ggagcactga gctcacagac tgacttgggc tcctactggt ggggacctct 1200

 gttagtcact ttacctcatc caaagtataa aggaattgga ccaaataatt 1250

 taccacatag ctctaaaact taatttaaaa tgtaattcca gaaaaaaaaa 1300

 gggaataagc aaagggggaa gaattgaaag agagagagaa gaaagaatac 1350

 agagagctta ccttttgcct ttctgttgat gttacatctc ttcttcctat 1400

 gttcttaggt ctatgagtct gtttccccat catttggtat ctagtccagt 1450

 tcctgcttac tgctttgcta atagctggcc ttgctagaat ccttggtttc 1500

 actgctgttc ttcatgtgct tctatgagat ttactccaac acaaatagga 1550

 ctgaatttat tgtgaagtaa cattggcaat cttaacttat tcatttaact 1600

 tatttttata gctagataaa tattgttagt cttagacaat agctcacatt 1650

 ttttgagaag catgccctcc ctgtccattt gtcttataac atgacccagc 1700

 cctattttac gtcattctaa attcagcctc atataatgaa aatacattat 1750

 gaaaacagat gtttaggaga tttcctgtat agcagtcagc caattcatat 1800

 gctttgtctc tgctggcttc tttttccatg cgttaacttt tcccaatagc 1850

 agaggaggca aatatgagca tacaatccct ttgttctaaa gatattgttc 1900

 cagctagtgg aatgatgttg aatctttaat aaccataatt agttgctttt 1950

 tcagtatctt ctgctttgtc tgtgtctatc cagtggccta ggaattaaag 2000

 tgtaagttgt tttcgctgtt aaattggata tttatatata tatatatagc 2050

 aagattttca tgtgttattt aattctgtat tgtttcttat atttgtagta 2100

 aaatattgaa caattaaaaa aaaaaaaaaa agaaaaaaaa aaaaaaa 2147

<210> 5986
<211> 269
<212> PRT
<213> Homo sapien

<400> 5986
 Met Glu Arg Leu Val Ile Arg Met Pro Phe Cys His Leu Ser Thr
   1               5                  10                  15

 Tyr Ser Leu Val Trp Val Met Ala Ala Val Val Leu Cys Thr Ala
                  20                  25                  30

 Gln Val Gln Val Val Thr Gln Asp Glu Arg Glu Gln Leu Tyr Thr
                  35                  40                  45

 Pro Ala Ser Leu Lys Cys Ser Leu Gln Asn Ala Gln Glu Ala Leu
                  50                  55                  60

 Ile Val Thr Trp Gln Lys Lys Lys Ala Val Ser Pro Glu Asn Met
                  65                  70                  75

 Val Thr Phe Ser Glu Asn His Gly Val Val Ile Gln Pro Ala Tyr
                  80                  85                  90

 Lys Asp Lys Ile Asn Ile Thr Gln Leu Gly Leu Gln Asn Ser Thr
                  95                 100                 105

 Ile Thr Phe Trp Asn Ile Thr Leu Glu Asp Glu Gly Cys Tyr Met
                 110                 115                 120

 Cys Leu Phe Asn Thr Phe Gly Phe Gly Lys Ile Ser Gly Thr Ala
                 125                 130                 135

 Cys Leu Thr Val Tyr Val Gln Pro Ile Val Ser Leu His Tyr Lys
                 140                 145                 150

 Phe Ser Glu Asp His Leu Asn Ile Thr Cys Ser Ala Thr Ala Arg
                 155                 160                 165

 Pro Ala Pro Met Val Phe Trp Lys Val Pro Arg Ser Gly Ile Glu
                 170                 175                 180

 Asn Ser Thr Val Thr Leu Ser His Pro Asn Gly Thr Thr Ser Val
                 185                 190                 195

 Thr Ser Ile Leu His Ile Lys Asp Pro Lys Asn Gln Val Gly Lys
                 200                 205                 210

 Glu Val Ile Cys Gln Val Leu His Leu Gly Thr Val Thr Asp Phe
                 215                 220                 225

 Lys Gln Thr Val Asn Lys Gly Tyr Trp Phe Ser Val Pro Leu Leu
                 230                 235                 240

 Leu Ser Ile Val Ser Leu Val Ile Leu Leu Val Leu Ile Ser Ile
                 245                 250                 255

 Leu Leu Tyr Trp Lys Arg His Arg Asn Gln Asp Arg Glu Pro
                 260                 265

<210> 5987
<211> 752
<212> DNA
<213> Homo sapien

<400> 5987
 actgaacagt ggttaatcct gactctgttt ttgactgaca gttaacagtt 50

 acatgaacca ttcatattac agctcttact taaatttgac caagccagga 100

 tatatctgtt aggccacatt catttaggga tcatgttttc caaagcaggt 150

 ttgggcaaaa ttaatccaca ggactgaaag gtatacatct gtgagttttg 200

 ttctcacttc cacctctaat ttgaagaaca ctttaattga cacagaatac 250

 atttcacata tttaacctct acaataagtt ctgacacatt ttccatgaaa 300

 caaaccatcg ctatattcaa gataatgaac ctatctatca tactcccaaa 350

 ttccttctkg catctttgta atttctcact cttccttctc cctctccccg 400

 tcccatccca accactgatc tgctcaggca actaccaatc ttctttctgt 450

 cactatagat taatttgcat ttttaaagaa atttacatac atggaaccat 500

 acatcatcta tgctttgtag tatgactcct gtcactcagt acaattattt 550

 tgagattcat ttatgttawt gtatgtatca atagttcatc ccttttattg 600

 gtaagtaaca tttttttgta taggtatacc atgatttgtt gatgaacaaa 650

 tttacctgtt gatgaacatt tacgttgtta ccaagatttt tgctattgaa 700

 aataaagttt ttatgaatat ttatatatat aaaaaaaaaa aaaaaaactc 750

 ga 752

<210> 5988
<211> 66
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 12
<223> unknown amino acid

<400> 5988
 Met Asn Leu Ser Ile Ile Leu Pro Asn Ser Phe Xaa His Leu Cys
   1               5                  10                  15

 Asn Phe Ser Leu Phe Leu Leu Pro Leu Pro Val Pro Ser Gln Pro
                  20                  25                  30

 Leu Ile Cys Ser Gly Asn Tyr Gln Ser Ser Phe Cys His Tyr Arg
                  35                  40                  45

 Leu Ile Cys Ile Phe Lys Glu Ile Tyr Ile His Gly Thr Ile His
                  50                  55                  60

 His Leu Cys Phe Val Val
                  65

<210> 5989
<211> 978
<212> DNA
<213> Homo sapien

<400> 5989
 gcaggacttt gtgtacagtt aaaggagaga tggccaagcc aggacaaatg 50

 tctattagaa aacggtccta agagattcta tggtgtttgg cactttaagg 100

 tcatcggtgg gcagaagttt agcattaata gttgttctga aacgtgttta 150

 tcaggtttag agcccatgtt gagtcttctt ttcatgggtt ttcataatat 200

 tttaaaacta tttgtttagc gatggttttg ttcgtttaag taaaggttaa 250

 tcttgatgat atacataata atctttctaa aattgtatgc tgaccatact 300

 tgctgtcaga ataatgctag gcatatgctt tttgctaaat atgtatgtac 350

 agagtatttg gaagttaaga attgattaga ctagtgaatt taggagtatt 400

 tgaggtgggt ggggggaaga gggaaatgac aactgcaaat gtagactata 450

 ctgtaaaaat tcagtttgtt gctttaaaga aacaaactga tacctgaatt 500

 ttgctgtgtt tccatttttt agagattttt atcatttttt tctctctctt 550

 ggcattcttt tttctcatac tcttcaaaaa gcagttctgc agctggttaa 600

 ttcatgtaac tgtgagagca aatgaataat tcctgctatt ctgaaattgc 650

 ctacatgttt caataccagt tatatggagt gcttgaattt aataagcagt 700

 ttttacggag tttacagtac agaaataggc tttaattttc aagtgaattt 750

 tttgccaaac ttagtaactc tgttaaatat ttggaggatt taaagaacat 800

 cccagtttga attcatttca aactttttaa atttttttgt actatgtttg 850

 gttttatttt ccttctgtta atcttttgta ttcacttatg ctctcgtaca 900

 ttgagtactt ttattccaaa actagtgggt tttctctact ggaaattttc 950

 aataaacctg tcattatcca aatacaac 978

<210> 5990
<211> 72
<212> PRT
<213> Homo sapien

<400> 5990
 Ala Gly Leu Cys Val Gln Leu Lys Glu Arg Trp Pro Ser Gln Asp
   1               5                  10                  15

 Lys Cys Leu Leu Glu Asn Gly Pro Lys Arg Phe Tyr Gly Val Trp
                  20                  25                  30

 His Phe Lys Val Ile Gly Gly Gln Lys Phe Ser Ile Asn Ser Cys
                  35                  40                  45

 Ser Glu Thr Cys Leu Ser Gly Leu Glu Pro Met Leu Ser Leu Leu
                  50                  55                  60

 Phe Met Gly Phe His Asn Ile Leu Lys Leu Phe Val
                  65                  70

<210> 5991
<211> 3425
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3397, 3409
<223> Unknown base

<400> 5991
 atgggtgggt aaaagtgaac gacagcttac aaattcaaaa ataaaactct 50

 tggttattaa agtcattcca ggcatggaca gagggatgcg aggctggcct 100

 tccctgtcca cggtcctctg aggcagctga agtctcccat gtctggaccc 150

 cgaatcttgt gcagattgaa cagtggatcc ggggtgctct gagcaggcag 200

 cagggagcag ctctggtgac gcttcatgtg gtagcctcac tctccattct 250

 ctgcccctct cgtgcccaca aacaccacca agagattcac ggtgagaaat 300

 atcagcaaac ccagatccca gatcaccaac tccatggtct taggacttcc 350

 ttggactgtc cttggatcta aggctgagac tttacccacg cagatttccg 400

 gaggctcttc ctctgcaaca gccactgaaa gcatgtgagg gacagcccca 450

 cagcaggaca gaacgtggaa ccacgggata ccactttcac cttgcttccc 500

 ctacatcatc caagccccag gaacagcaca tgactcttac aagcaccgca 550

 gctcagcctc ttcttgaaga cacgtcacct ggggccactg ggcacacagg 600

 acagaggtca gctgacaatc ctgggacctc aggatccatg ctctcccaga 650

 ggacgcctct cacacacatg gggcggcagt catgttacac tcccaggggc 700

 attctcaccc cgcggacagt ggaagcccct cagggggtgc agaacagagt 750

 gctgcaggag agagagggcg ctggctggtg cgaagccgtc cgaggtgcag 800

 cacagcccac aaggcccgcc agtgtctttc ccgaggacac gcgaatcctg 850

 gggggctcac tccggcaaag aggacgagac actgcaccaa ggacagggcc 900

 tgacctctct ggccgccttc cccggggcct cagtttcccc cgatggtgag 950

 agtggagccg accatgcgcc ctgctgtgga ctcacccggc gccctggcgt 1000

 cgagtggcgg cggagacctg acagacagcg tgggaaaaat caagatgtct 1050

 gcagatttcg agagatgggg tgcggtggcg ggcgctggcg gcggcggagg 1100

 agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg 1150

 agccacctcc ctccctgcag cccgcaacgg gaatggagta aagggagacc 1200

 cgtcgacctg gccacgggga tcagcgatgg aattaaagca atctttgtcc 1250

 acccatctgg aagccgagaa gcctctgagg cgctatgggg cggtggagga 1300

 gacggcttgg aaaacggaga gactggggag aaatcagctg gacatcatct 1350

 ccatggcgga gacaaccatg atgccagagg agattgagct ggagatggca 1400

 aaaattcagc gtctccggga agtcttggtc cgccgggagt ctgagctcag 1450

 gttcatgatg gatgacatcc agctctgcaa ggacatcatg gacttgaagc 1500

 aggagctgca gaacttggtc gccatcccag aaaaagaaaa aaccaaactg 1550

 cagaagcaga gagaggatga gctaatccag aagatccaca aactggtgca 1600

 gaagagagac ttcctggtgg acgatgcgga ggtcgagcgg ttaagggagc 1650

 aagaagaaga caaggaaatg gctgatttcc tgagaatcaa gttaaaacct 1700

 ctagacaaag taaccaaatc tccagccagc tcccgggcag agaagaaagc 1750

 agagccccca cctagcaagc ccacggtggc caagacgggg ctggcactga 1800

 tcaaggattg ttgcggggcc acccagtgca acatcatgta gcccccacgt 1850

 ggggtgccct gggccatggg gacccccccc caccctcttg tctttatagc 1900

 ccccatttca ccggggccca agagctctcc aaggcagaag gggttgaagg 1950

 caagcccgtg actgtcacca gaggccatgg gcacggcagg cgggcctggc 2000

 caccctgtac agagtgtagc agtagggagt ctctcaccgt cgcatggtcc 2050

 tccccagagc atgccgaacc caggagtctg tctcactgtt tatccaaaca 2100

 ccaggaaagg tcctccctca aaaaagcata tctccacttc tctctagctg 2150

 tatctaaccc accgtgtgaa tgaactggga gaggggcatg ctccccagct 2200

 gtgtgtagtc gtgacttctc aacaatctag caccatgtcg gacacgttcc 2250

 ccatccaccc tcctagctct gctctcagag ctaggcacat gggcacaggt 2300

 cccctcccgt ctgtcctctc ccagcaactg tgccctggag ggctccacat 2350

 ggcccccgtg tctctcgggc accacccata tagcagtccc agagggccca 2400

 tctgtaaaga tcgagcttgt gtgtggtgtc gtggtcacat ctcccgcttc 2450

 cccccatcct gtgtctgggc acagttcaca tcaggacagc gtccattgtg 2500

 ctctcagtct gcctcaggtg tgtgcctgga gggggcctgg actggcatgg 2550

 atccagtgtg cagaagagcc agcagggaac cggaagctct gatgtcaagg 2600

 ccagagcagt tgagaatggg acccagagta gatgctgacc tgggcactcc 2650

 accattccgg ggccaccaca gagatgccag caggatgcca ctttgccagc 2700

 ccgacacacg gacctttgta aagaacagca acaggcagga gaggcagcgt 2750

 gtgaccagat tgtgtcccgt cattgggtgg catatgttaa ctagctgcca 2800

 aacaacttca acccgtgtaa ttcatgtaca tttgcaacag ccagcccggt 2850

 acagcctgtg tgacttctct gtatgtgtgt gtgtgtcgtg accagcctaa 2900

 gtagttagca taactcaaga tgctgatgtg cagtcaccca tcagagaaaa 2950

 taaaaatgga aaccacgttc acagcatttt aaaagttttt actttttttc 3000

 ttgattatgg aagtaatcca tgtacatagt aaatcatttt aaaagtacaa 3050

 aaagtatgaa gaagtttgtc ttaaaaaaaa aaaaattatt cctccaacta 3100

 gagaccactc tgatgtttcg acgttttaaa aaagtctttt tttgtgcatt 3150

 ttttcatcgt tgacatcata ttgtgatatc atttataacc agttttttcc 3200

 tacttattat accaccatct tccacatcat taaaagctct ttgtaaacat 3250

 taaacactct tcataaatca tgccaatgtc tgtttagtaa tccatcttgt 3300

 ggatgtactg taattcatct aatcatttcc tcactattgg atgtgtagac 3350

 tggttctagg ttttcttata aatagtgtct tggattagcc aggcatngta 3400

 atgggtgcng taatcccagc tactt 3425

<210> 5992
<211> 258
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 3397, 3409
<223> Unknown amino acid

<400> 5992
 Met Gly Cys Gly Gly Gly Arg Trp Arg Arg Arg Arg Arg Gly Ser
   1               5                  10                  15

 Ser Val Thr Gly Ala Arg Pro Val Lys Thr Leu Leu Ala Gly Ala
                  20                  25                  30

 Thr Ser Leu Pro Ala Ala Arg Asn Gly Asn Gly Val Lys Gly Asp
                  35                  40                  45

 Pro Ser Thr Trp Pro Arg Gly Ser Ala Met Glu Leu Lys Gln Ser
                  50                  55                  60

 Leu Ser Thr His Leu Glu Ala Glu Lys Pro Leu Arg Arg Tyr Gly
                  65                  70                  75

 Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg Leu Gly Arg Asn
                  80                  85                  90

 Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met Met Pro Glu
                  95                 100                 105

 Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg Glu Val
                 110                 115                 120

 Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp Ile
                 125                 130                 135

 Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn
                 140                 145                 150

 Leu Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln Lys Gln
                 155                 160                 165

 Arg Glu Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln Lys
                 170                 175                 180

 Arg Asp Phe Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu
                 185                 190                 195

 Gln Glu Glu Asp Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu
                 200                 205                 210

 Lys Pro Leu Asp Lys Val Thr Lys Ser Pro Ala Ser Ser Arg Ala
                 215                 220                 225

 Glu Lys Lys Ala Glu Pro Pro Pro Ser Lys Pro Thr Val Ala Lys
                 230                 235                 240

 Thr Gly Leu Ala Leu Ile Lys Asp Cys Cys Gly Ala Thr Gln Cys
                 245                 250                 255

 Asn Ile Met


<210> 5993
<211> 3568
<212> DNA
<213> Homo sapien

<400> 5993
 gaagtagcaa ctaaagtggc agtgtttctt ctgaaattct caggcagtca 50

 gactgtctta ggcaaatctt gataaaatag cccttatcca ggtttttatc 100

 taaggaatcc caagaagact ggggaatgga gagacagtca agggttatgt 150

 cagaaaagga tgagtatcag tttcaacatc agggagcggt ggagctgctt 200

 gtcttcaatt ttttgctcat ccttaccatt ttgacaatct ggttatttaa 250

 aaatcatcga ttccgcttct tgcatgaaac tggaggagca atggtgtatg 300

 gccttataat gggactaatt ttacgatatg ctacagcacc aactgatatt 350

 gaaagtggaa ctgtctatga ctgtgtaaaa ctaactttca gtccatcaac 400

 tctgctggtt aatatcactg accaagttta tgaatataaa tacaaaagag 450

 aaataagtca gcacaacatc aatcctcatc aaggaaatgc tatacttgaa 500

 aagatgacat ttgatccaga aatcttcttc aatgttttac tgccaccaat 550

 tatatttcat gcaggatata gtctaaagaa gagacacttt tttcaaaact 600

 taggatctat tttaacgtat gccttcttgg gaactgccat ctcctgcatc 650

 gtcatagggt taattatgta tggttttgtg aaggctatga tacatgctgg 700

 ccagctgaaa aatggagact ttcatttcac tgactgttta ttttttggtt 750

 cactgatgtc tgctacagat ccagtgacag tgctggccat tttccatgaa 800

 ctgcacgtcg accctgacct gtacacactc ttgtttggag agagtgtgtt 850

 gaatgatgca gtggccatag tccttacata ttctatatcc atttacagtc 900

 ccaaggagaa tccaaatgca tttgatgccg cagcattctt ccagtctgtg 950

 gggaatttcc tgggaatctt cgctggctca tttgcaatgg ggtctgcgta 1000

 tgccatcatc acagcactgt tgaccaaatt taccaagctg tgtgagttcc 1050

 cgatgctgga aaccggcctg tttttcctgc tttcttggag tgccttcctg 1100

 tctgccgagg ctgccggcct aacagggata gttgctgttc tcttctgtgg 1150

 agtcacacaa gcacattata cctacaacaa tctgtcttcg gattccaaaa 1200

 taagaactaa acagttgttt gaatttatga actttttggc ggagaacgtc 1250

 atcttctgtt acatgggcct ggcactgttc acgttccaga atcatatctt 1300

 taatgctctt tttatacttg gagcctttct agcaattttt gttgccagag 1350

 cctgcaacat atatcccctc tccttcctcc tgaatctagg ccgaaaacag 1400

 aagatcccct ggaactttca gcacatgatg atgttttcag gtttgcgagg 1450

 agcgatcgca tttgccttag ctattcggaa cacagaatct cagcccaaac 1500

 aaatgatgtt taccactacg ctgctcctcg tgttcttcac tgtctgggta 1550

 tttggaggag gaacaacccc catgttgact tggcttcaga tcagagttgg 1600

 cgtggacctg gatgaaaatc tgaaggagga cccctcctca caacaccagg 1650

 aagcaaataa cttggataaa aacatgacga aagcagagag tgctcggctc 1700

 ttcagaatgt ggtatagctt tgaccacaag tatctgaaac caattttaac 1750

 ccactctggt cctccgctga ctacaacatt acctgaatgg tgtggtccga 1800

 tttccaggct gcttaccagt cctcaagcct atggggaaca gctaaaagag 1850

 gatgatgtgg aatgcattgt aaaccaggat gaactagcca taaattacca 1900

 ggagcaagcc tcctcaccct gcagtcctcc tgcaaggcta ggtctggacc 1950

 agaaagcttc accccagacg ccaggcaagg aaaacattta tgagggagac 2000

 ctcggcctgg gaggctatga actcaagctt gagcaaactt tgggtcaatc 2050

 ccagttgaat taattggcat gaagagtaca gatgtaatca caagtaatgc 2100

 aagactcact gaggaataca agccaagctg atgaggcagt acaggggaga 2150

 ggctggaaaa catattaaga gcataaattg gagagaatca aagccttgtc 2200

 acatggatcc tctggtgcct gaagaaatga gattttatta tccctctcta 2250

 ttatgcaaat gaatttagtt ttttgacagc agccattctg attactggat 2300

 tggctggggt ggggatgggg gtatcaggag tctagctgct ggaggatggg 2350

 acagctgtgc tgggtcttca gggcatttct gctgcgaatg cggctctcca 2400

 ggcccttcac ttctattctg gattttattc cctccattaa ggagagttta 2450

 aaaataaaag aaagcttctg agagtaaaca ttttgctcct aagctgaagg 2500

 gaatgcccag ctatttagta agtgataagt ttcttatttt gaggacttga 2550

 ctcccatttg ctctcagtga ccccagggca gagcccagag aagtgttccg 2600

 tacccactgc tgatggtttc ccagagccca cactgagttg aagaacctat 2650

 tgttcttctt ggcatccttc ttatgctact tctcccatcg ctcaaagggg 2700

 ttgcctatgg ctgggtgtgc cctgccctaa atgcagcacc actttcaagc 2750

 ttagtaggac cattccaaga aaaccaggtt tcttctcccc ataccacgtt 2800

 gtgcctgaag aacaagcctt cccgtccttg cctgcatgtg agtcacttct 2850

 tggctgtgca gcaggtcccc cccctccccg cgatatgctg gagggtagga 2900

 ttctgcagcc tgtgttgctc tctacctggc agcagactgt gcaggagccc 2950

 caacctgtcc tccaattcca gcattcacag ctgatgagca gtgcaggagc 3000

 agggcgagag gaacagagcc aatgatgtgt gggttacact gaggagccaa 3050

 ggacagggcc tcaggtctcc cccttacaag gcgtggctca tggcctgcat 3100

 tccagagacc aacatgatag cttttaattc agctgcatga cctgtgcctt 3150

 ttaagccata aagatacctc aagcctagca cctcttgaaa tccagatgtt 3200

 catattagac tcgaaaaaat aggctccagg cctaggtgcc caggctatga 3250

 tgagtctgct tttgaaggag gtagggaatg acatcttcct tggacccaaa 3300

 gcttaaaagt aatgtatgct ttgctgacca ctgtttgtta ggccttaaac 3350

 aacattcact gtggtggtat caggcacact gctatgtgca tcaattattt 3400

 ttttgctttc caaacagaat ctctggggca caagttttac actcaagcta 3450

 agtataactt tgtcatttca ggtaaatatg acaagtggtg gagcatgaag 3500

 ttttctaatt tgacttaatc ctaataaatt tttgttacaa agtaaaaaaa 3550

 aaaaaaaaaa aaaaaaaa 3568

<210> 5994
<211> 645
<212> PRT
<213> Homo sapien

<400> 5994
 Met Glu Arg Gln Ser Arg Val Met Ser Glu Lys Asp Glu Tyr Gln
   1               5                  10                  15

 Phe Gln His Gln Gly Ala Val Glu Leu Leu Val Phe Asn Phe Leu
                  20                  25                  30

 Leu Ile Leu Thr Ile Leu Thr Ile Trp Leu Phe Lys Asn His Arg
                  35                  40                  45

 Phe Arg Phe Leu His Glu Thr Gly Gly Ala Met Val Tyr Gly Leu
                  50                  55                  60

 Ile Met Gly Leu Ile Leu Arg Tyr Ala Thr Ala Pro Thr Asp Ile
                  65                  70                  75

 Glu Ser Gly Thr Val Tyr Asp Cys Val Lys Leu Thr Phe Ser Pro
                  80                  85                  90

 Ser Thr Leu Leu Val Asn Ile Thr Asp Gln Val Tyr Glu Tyr Lys
                  95                 100                 105

 Tyr Lys Arg Glu Ile Ser Gln His Asn Ile Asn Pro His Gln Gly
                 110                 115                 120

 Asn Ala Ile Leu Glu Lys Met Thr Phe Asp Pro Glu Ile Phe Phe
                 125                 130                 135

 Asn Val Leu Leu Pro Pro Ile Ile Phe His Ala Gly Tyr Ser Leu
                 140                 145                 150

 Lys Lys Arg His Phe Phe Gln Asn Leu Gly Ser Ile Leu Thr Tyr
                 155                 160                 165

 Ala Phe Leu Gly Thr Ala Ile Ser Cys Ile Val Ile Gly Leu Ile
                 170                 175                 180

 Met Tyr Gly Phe Val Lys Ala Met Ile His Ala Gly Gln Leu Lys
                 185                 190                 195

 Asn Gly Asp Phe His Phe Thr Asp Cys Leu Phe Phe Gly Ser Leu
                 200                 205                 210

 Met Ser Ala Thr Asp Pro Val Thr Val Leu Ala Ile Phe His Glu
                 215                 220                 225

 Leu His Val Asp Pro Asp Leu Tyr Thr Leu Leu Phe Gly Glu Ser
                 230                 235                 240

 Val Leu Asn Asp Ala Val Ala Ile Val Leu Thr Tyr Ser Ile Ser
                 245                 250                 255

 Ile Tyr Ser Pro Lys Glu Asn Pro Asn Ala Phe Asp Ala Ala Ala
                 260                 265                 270

 Phe Phe Gln Ser Val Gly Asn Phe Leu Gly Ile Phe Ala Gly Ser
                 275                 280                 285

 Phe Ala Met Gly Ser Ala Tyr Ala Ile Ile Thr Ala Leu Leu Thr
                 290                 295                 300

 Lys Phe Thr Lys Leu Cys Glu Phe Pro Met Leu Glu Thr Gly Leu
                 305                 310                 315

 Phe Phe Leu Leu Ser Trp Ser Ala Phe Leu Ser Ala Glu Ala Ala
                 320                 325                 330

 Gly Leu Thr Gly Ile Val Ala Val Leu Phe Cys Gly Val Thr Gln
                 335                 340                 345

 Ala His Tyr Thr Tyr Asn Asn Leu Ser Ser Asp Ser Lys Ile Arg
                 350                 355                 360

 Thr Lys Gln Leu Phe Glu Phe Met Asn Phe Leu Ala Glu Asn Val
                 365                 370                 375

 Ile Phe Cys Tyr Met Gly Leu Ala Leu Phe Thr Phe Gln Asn His
                 380                 385                 390

 Ile Phe Asn Ala Leu Phe Ile Leu Gly Ala Phe Leu Ala Ile Phe
                 395                 400                 405

 Val Ala Arg Ala Cys Asn Ile Tyr Pro Leu Ser Phe Leu Leu Asn
                 410                 415                 420

 Leu Gly Arg Lys Gln Lys Ile Pro Trp Asn Phe Gln His Met Met
                 425                 430                 435

 Met Phe Ser Gly Leu Arg Gly Ala Ile Ala Phe Ala Leu Ala Ile
                 440                 445                 450

 Arg Asn Thr Glu Ser Gln Pro Lys Gln Met Met Phe Thr Thr Thr
                 455                 460                 465

 Leu Leu Leu Val Phe Phe Thr Val Trp Val Phe Gly Gly Gly Thr
                 470                 475                 480

 Thr Pro Met Leu Thr Trp Leu Gln Ile Arg Val Gly Val Asp Leu
                 485                 490                 495

 Asp Glu Asn Leu Lys Glu Asp Pro Ser Ser Gln His Gln Glu Ala
                 500                 505                 510

 Asn Asn Leu Asp Lys Asn Met Thr Lys Ala Glu Ser Ala Arg Leu
                 515                 520                 525

 Phe Arg Met Trp Tyr Ser Phe Asp His Lys Tyr Leu Lys Pro Ile
                 530                 535                 540

 Leu Thr His Ser Gly Pro Pro Leu Thr Thr Thr Leu Pro Glu Trp
                 545                 550                 555

 Cys Gly Pro Ile Ser Arg Leu Leu Thr Ser Pro Gln Ala Tyr Gly
                 560                 565                 570

 Glu Gln Leu Lys Glu Asp Asp Val Glu Cys Ile Val Asn Gln Asp
                 575                 580                 585

 Glu Leu Ala Ile Asn Tyr Gln Glu Gln Ala Ser Ser Pro Cys Ser
                 590                 595                 600

 Pro Pro Ala Arg Leu Gly Leu Asp Gln Lys Ala Ser Pro Gln Thr
                 605                 610                 615

 Pro Gly Lys Glu Asn Ile Tyr Glu Gly Asp Leu Gly Leu Gly Gly
                 620                 625                 630

 Tyr Glu Leu Lys Leu Glu Gln Thr Leu Gly Gln Ser Gln Leu Asn
                 635                 640                 645

<210> 5995
<211> 2920
<212> DNA
<213> Homo sapien

<400> 5995
 cgccaggaga ccccaagctg catcgccgag tggaagcaac tagaactcca 50

 gggctgtgaa agccacaggt gggggctgag cgaggcgtgg cctcaggagc 100

 ggaggacccc cccccactct ccctcgagcg ccgcagtcca ccgtagcggg 150

 tggagcccgc cttggtgcgc agttggaaaa cctcggagcc ccgctggatc 200

 tcctggctgc cacccgcacc ccccgccagc ctacgcccca ccgtagagat 250

 gccttcttcg gtgacggcgc tgggtcaggc caggtcctct ggccccggga 300

 tggccccgag cgcctgctgc tgctcccctg cggccctgca gaggaggctg 350

 cccatcctgg cgtggctgcc cagctactcc ctgcagtggc tgaagatgga 400

 tttcgtcgcc ggcctctcag ttggcctcac tgccattccc caggcgctgg 450

 cctatgctga agtggctgga ctcccgcccc agtatggcct ctactctgcc 500

 ttcatgggct gcttcgtgta tttcttcctg ggcacctccc gggatgtgac 550

 tctgggcccc accgccatta tgtccctcct ggtctccttc tacaccttcc 600

 atgagcccgc ctacgctgtg ctgctggcct tcctgtccgg ctgcatccag 650

 ctggccatgg gggtcctgcg tttggggttc ctgctggact tcatttccta 700

 ccccgtcatt aaaggcttca cctctgctgc tgccgtcacc atcggctttg 750

 gacagatcaa gaacctgctg ggactacaga acatccccag gccgttcttc 800

 ctgcaggtgt accacacctt cctcaggatt gcagagacca gggtaggtga 850

 cgccgtcctg gggctggtct gcatgctgct gctgctggtg ctgaagctga 900

 tgcgggacca cgtgcctccc gtccaccccg agatgccccc tggtgtgcgg 950

 ctcagccgtg ggctggtctg ggctgccacg acagctcgca acgccctggt 1000

 ggtctccttc gcagccctgg ttgcgtactc cttcgaggtg actggatacc 1050

 agcctttcat cctaacaggg gagacagctg aggggctccc tccagtccgg 1100

 atcccgccct tctcagtgac cacagccaac gggacgatct ccttcaccga 1150

 gatggtgcag gacatgggag ccgggctggc cgtggtgccc ctgatgggcc 1200

 tcctggagag cattgcggtg gccaaagcct tcgcatctca gaataattac 1250

 cgcatcgatg ccaaccagga gctgctggcc atcggtctca ccaacatgtt 1300

 gggctccctc gtctcctcct acccggtcac aggcagcttt ggacggacag 1350

 ccgtgaacgc tcagtcgggg gtgtgcaccc cggcgggggg cctggtgacg 1400

 ggagtgctgg tgctgctgtc tctggactac ctgacctcac tgttctacta 1450

 catccccaag tctgccctgg ctgccgtcat catcatggcc gtggccccgc 1500

 tgttcgacac caagatcttc aggacgctct ggcgtgttaa gaggctggac 1550

 ctgctgcccc tgtgcgtgac cttcctgctg tgcttctggg aggtgcagta 1600

 cggcatcctg gccggggccc tggtgtctct gctcatgctc ctgcactctg 1650

 cagccaggcc tgagaccaag gtgtcagagg ggccggttct ggtcctgcag 1700

 ccggccagcg gcctgtcctt ccctgccatg gaggctctgc gggaggagat 1750

 cctaagccgg gccctggaag tgtccccgcc acgctgcctg gtcctggagt 1800

 gcacccatgt ctgcagcatc gactacactg tggtgctggg actcggcgag 1850

 ctcctccagg acttccagaa gcagggcgtc gccctggcct ttgtgggcct 1900

 gcaggtcccc gttctccgtg tcctgctgtc cgctgacctg aaggggttcc 1950

 agtacttctc taccctggaa gaagcagaga agcacctgag gcagaagcca 2000

 gggacccagc cctacaacat cagagaagac tccattctgg accaaaaggt 2050

 tgccctgctc aaggcataat ggggccaccc gtgggcatcc acagtttgca 2100

 gggtgttccg gaaggttctt gtcactgtga ttggatgctg gatgccgcct 2150

 gatagacatg ctggcctggc tgagaaaccc ctgagcaggt aacccaggga 2200

 agagaaggaa gccaggcctg gaggtccacg gcagtgggag tggggctcac 2250

 tggcttcctg tgggatgact ggaaaatgac ctcgctgctg ttccctggca 2300

 tgaccctctt tggaagagtg gtttggagag agccttctag aatgacagac 2350

 tgtgcgagga agcaggggca ggggtttcca gcccgggctg tgcgaggcat 2400

 cctggggctg gcagcacctt cccggctcac cagtgccacc tgcgggggag 2450

 ggacggggca ggcaggagtc tgggaggcgg gtccgctcct cttgtctgcg 2500

 gcatctgtgc tctccgagag aaaaccaagg tgtgtcaaat gacgtcaagt 2550

 ctctatttaa aaataatttt gtgttttcta aatggaaaaa gtgatagctt 2600

 tggtgatttt gtaaaagtca taaatgctta ttgtaaaaaa tacaggaaac 2650

 cacccctcac cctgtccact tgggtgatca ttccagaccc ctccccaaac 2700

 atgcatatgt acctgtccgt cagtgtgtgg atgtatgttt acagttctac 2750

 ataaatggga tcattttata catggtgctc tggaacccac atttttcatg 2800

 cagtcatttg cagtgaatta tttattgtga taataaatag cattagaata 2850

 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2900

 aaaaaaaaaa aaaaaaaaaa 2920

<210> 5996
<211> 589
<212> PRT
<213> Homo sapien

<400> 5996
 Met Ala Pro Ser Ala Cys Cys Cys Ser Pro Ala Ala Leu Gln Arg
   1               5                  10                  15

 Arg Leu Pro Ile Leu Ala Trp Leu Pro Ser Tyr Ser Leu Gln Trp
                  20                  25                  30

 Leu Lys Met Asp Phe Val Ala Gly Leu Ser Val Gly Leu Thr Ala
                  35                  40                  45

 Ile Pro Gln Ala Leu Ala Tyr Ala Glu Val Ala Gly Leu Pro Pro
                  50                  55                  60

 Gln Tyr Gly Leu Tyr Ser Ala Phe Met Gly Cys Phe Val Tyr Phe
                  65                  70                  75

 Phe Leu Gly Thr Ser Arg Asp Val Thr Leu Gly Pro Thr Ala Ile
                  80                  85                  90

 Met Ser Leu Leu Val Ser Phe Tyr Thr Phe His Glu Pro Ala Tyr
                  95                 100                 105

 Ala Val Leu Leu Ala Phe Leu Ser Gly Cys Ile Gln Leu Ala Met
                 110                 115                 120

 Gly Val Leu Arg Leu Gly Phe Leu Leu Asp Phe Ile Ser Tyr Pro
                 125                 130                 135

 Val Ile Lys Gly Phe Thr Ser Ala Ala Ala Val Thr Ile Gly Phe
                 140                 145                 150

 Gly Gln Ile Lys Asn Leu Leu Gly Leu Gln Asn Ile Pro Arg Pro
                 155                 160                 165

 Phe Phe Leu Gln Val Tyr His Thr Phe Leu Arg Ile Ala Glu Thr
                 170                 175                 180

 Arg Val Gly Asp Ala Val Leu Gly Leu Val Cys Met Leu Leu Leu
                 185                 190                 195

 Leu Val Leu Lys Leu Met Arg Asp His Val Pro Pro Val His Pro
                 200                 205                 210

 Glu Met Pro Pro Gly Val Arg Leu Ser Arg Gly Leu Val Trp Ala
                 215                 220                 225

 Ala Thr Thr Ala Arg Asn Ala Leu Val Val Ser Phe Ala Ala Leu
                 230                 235                 240

 Val Ala Tyr Ser Phe Glu Val Thr Gly Tyr Gln Pro Phe Ile Leu
                 245                 250                 255

 Thr Gly Glu Thr Ala Glu Gly Leu Pro Pro Val Arg Ile Pro Pro
                 260                 265                 270

 Phe Ser Val Thr Thr Ala Asn Gly Thr Ile Ser Phe Thr Glu Met
                 275                 280                 285

 Val Gln Asp Met Gly Ala Gly Leu Ala Val Val Pro Leu Met Gly
                 290                 295                 300

 Leu Leu Glu Ser Ile Ala Val Ala Lys Ala Phe Ala Ser Gln Asn
                 305                 310                 315

 Asn Tyr Arg Ile Asp Ala Asn Gln Glu Leu Leu Ala Ile Gly Leu
                 320                 325                 330

 Thr Asn Met Leu Gly Ser Leu Val Ser Ser Tyr Pro Val Thr Gly
                 335                 340                 345

 Ser Phe Gly Arg Thr Ala Val Asn Ala Gln Ser Gly Val Cys Thr
                 350                 355                 360

 Pro Ala Gly Gly Leu Val Thr Gly Val Leu Val Leu Leu Ser Leu
                 365                 370                 375

 Asp Tyr Leu Thr Ser Leu Phe Tyr Tyr Ile Pro Lys Ser Ala Leu
                 380                 385                 390

 Ala Ala Val Ile Ile Met Ala Val Ala Pro Leu Phe Asp Thr Lys
                 395                 400                 405

 Ile Phe Arg Thr Leu Trp Arg Val Lys Arg Leu Asp Leu Leu Pro
                 410                 415                 420

 Leu Cys Val Thr Phe Leu Leu Cys Phe Trp Glu Val Gln Tyr Gly
                 425                 430                 435

 Ile Leu Ala Gly Ala Leu Val Ser Leu Leu Met Leu Leu His Ser
                 440                 445                 450

 Ala Ala Arg Pro Glu Thr Lys Val Ser Glu Gly Pro Val Leu Val
                 455                 460                 465

 Leu Gln Pro Ala Ser Gly Leu Ser Phe Pro Ala Met Glu Ala Leu
                 470                 475                 480

 Arg Glu Glu Ile Leu Ser Arg Ala Leu Glu Val Ser Pro Pro Arg
                 485                 490                 495

 Cys Leu Val Leu Glu Cys Thr His Val Cys Ser Ile Asp Tyr Thr
                 500                 505                 510

 Val Val Leu Gly Leu Gly Glu Leu Leu Gln Asp Phe Gln Lys Gln
                 515                 520                 525

 Gly Val Ala Leu Ala Phe Val Gly Leu Gln Val Pro Val Leu Arg
                 530                 535                 540

 Val Leu Leu Ser Ala Asp Leu Lys Gly Phe Gln Tyr Phe Ser Thr
                 545                 550                 555

 Leu Glu Glu Ala Glu Lys His Leu Arg Gln Lys Pro Gly Thr Gln
                 560                 565                 570

 Pro Tyr Asn Ile Arg Glu Asp Ser Ile Leu Asp Gln Lys Val Ala
                 575                 580                 585

 Leu Leu Lys Ala


<210> 5997
<211> 1566
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 501
<223> Unknown base

<400> 5997
 atcaacttat aatattgaat taatgttaat agtgtcattt taggtgaact 50

 agacttcatt gaaggaggtg ggagccttat ggagagagag tatatgatta 100

 tctctatttg tatttaatta ccatttcatc taaccattca gaacatattt 150

 caagaataat tttaattcaa gttgtagata aaacttacta taccattttc 200

 attttgacgc tttccaagaa tgagatacac ggtattttaa agacaaagat 250

 tgatcttaca tgttactatt aaaaaaaaca cgataatttt gttctacatt 300

 tatactttta atttttctgt ggataataag aaatgccaag agtcgattgt 350

 gtccatgctg gcaagtggcc taataaattg tccttttatt tggtggtcct 400

 cagagtggca gttaacatct tgctattctg ccttgtggac ttgaggtgga 450

 aaggttcatg gaattatatc cttgcttttg gatgtgcaaa ctgaggctca 500

 nagagtttaa gacacatagt cactttcacc aattaaatga tgaagctgcc 550

 atgtaaacgt atttcatcac actcccgaga ccttcttctc cagtagtgtt 600

 ttcaagcttt ttgagcatgc agacactacc atcaaaaaat tatgtagaga 650

 catacttgag agttacagtt taaagaaaaa caaggtgtaa ttatttggtt 700

 attagtagca tttacatatg cttgaaaact tctgctatat atacagtaag 750

 attaatttat tctaacaatg atcttgataa tccccctgat tcccagactc 800

 cttggaatag ctccacagct atcagtggtt ctgccacagg ttcagagcct 850

 tcccagtact gccttcttat ttgagaggtg tgctaagagc tataaagcag 900

 aggcttcaat tgtacacagt ttggaagttt aggcaaaagt catttcttcc 950

 ctatattttg tcatgcttat ctcctgtctc tttctgtttt acagattagc 1000

 aataaactcc ttaaaaccca aaggtttggg cttctgttcc tttcacttgc 1050

 agtcagacat ggagttagtg gagaagacga cagaaggggt aacctgcatg 1100

 gtgacagcta ctgaggggat ggataggaaa gcaggctgag tccctggggc 1150

 cagtggttac caaagccaag gagagagcaa ggggagccca gtgggcctgg 1200

 ccatggactg ctctggaatt ccgagtgtga actttcagcc aagaaggtag 1250

 tgtgaaaata ttactgtgag gttttaaaag tacacaaata acaattgttt 1300

 tttgtaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaga tatgccaaaa 1350

 aaaaaaaaaa aaaaaaaaaa aaaattgtgt cttctgttaa catattaaaa 1400

 tttattcttt tagattttta tgtgtctata tacatgtaaa atatatatgc 1450

 atccccaaat tgtattatac tcttttgaga cctcacattt ttttcaccca 1500

 agaatataac attaatttct ttcctttaga aaagacatga gactaaagaa 1550

 tgtttattga gttgag 1566

<210> 5998
<211> 1316
<212> DNA
<213> Homo sapien

<400> 5998
 cactcattaa gaacagagga ggctgcctgt tactcctggt gttgcatccc 50

 tccagacact ctgctgtttc ctgcctaggc gtggctgcag ccatggctag 100

 gaaagcgctg ccacccaccc acctgggcca gagctggttc tgctcctgct 150

 gcagggacac tgagctggct atctcggcgc ttcgggcaag aactgcaaca 200

 ggctctcctg ggtcctgcag gtgtacagcc gggcccctgc cttgtgcctc 250

 agctctcgag agctgctgct gccgggtgac ctgatccaac ctgataaggt 300

 gccatcttca gctaccactg caaggccctg agggcaacag cagcacggca 350

 ctgcccaccc ggctgctgat ggcctggtgc cagctgggag tcctcccggc 400

 acttcgaggc cactgagcca cccttccagc cccagcccac catggacagg 450

 ggtatccagc ttcctcctca acctcgtcct ctgcccctga gccagtgacg 500

 cccaaggaca tgcctgttac ccaggtcctg taccagcact agctggtcaa 550

 gggcatgaca gtgctggagg ccgtcttgga gatccaggcc atcactggca 600

 gcaggctgct ctccatggtg ccagggcccg ccaggccacc aggctcatgc 650

 tgggacccaa cccagtgcac aaggacttgg ctgctgagcc acacacccag 700

 gagaaggtgg ataagtgggc taccaagggc ttcctgcagg ctaggggagg 750

 agccaccccc gcttccctat tgtgaccagg cctatgggga ggagctgtcc 800

 atacgccacc gtgagacctg ggcctggctc tcaaggacag acaccgcctg 850

 gcctggtgct ccaggggtga agcaggccag aatcctgggg gagctgctcc 900

 tggtttgagc tgcattcagg aagtgcggga catggtaggg gaggcaaaaa 950

 gccttgggca ctaccctccc tgtggagctg ttcggtgtcc gtcgagctag 1000

 ccacaccctg acaccatgtt caagggtacc ggaagagaag ggtgtctgcc 1050

 cccaacctcc cctgtgggtg tcactggcca gatgtcatga gggaagcagg 1100

 ccttgtgagt ggacactgac catgagtccc tggggggagt gatcccccag 1150

 gcatcgtgtg ccatgttgca cttctgccca ggcagcaggg tgggtgggta 1200

 ccatgggtgc ccacccctcc accacatggg gccccaaagc actgcaggcc 1250

 aagcagggca accccacacc cttgacataa aagcatcttg aagcttttaa 1300

 aaaaaaaaaa aaaaaa 1316

<210> 5999
<211> 117
<212> PRT
<213> Homo sapien

<400> 5999
 Met Thr Val Leu Glu Ala Val Leu Glu Ile Gln Ala Ile Thr Gly
   1               5                  10                  15

 Ser Arg Leu Leu Ser Met Val Pro Gly Pro Ala Arg Pro Pro Gly
                  20                  25                  30

 Ser Cys Trp Asp Pro Thr Gln Cys Thr Arg Thr Trp Leu Leu Ser
                  35                  40                  45

 His Thr Pro Arg Arg Arg Trp Ile Ser Gly Leu Pro Arg Ala Ser
                  50                  55                  60

 Cys Arg Leu Gly Glu Glu Pro Pro Pro Leu Pro Tyr Cys Asp Gln
                  65                  70                  75

 Ala Tyr Gly Glu Glu Leu Ser Ile Arg His Arg Glu Thr Trp Ala
                  80                  85                  90

 Trp Leu Ser Arg Thr Asp Thr Ala Trp Pro Gly Ala Pro Gly Val
                  95                 100                 105

 Lys Gln Ala Arg Ile Leu Gly Glu Leu Leu Leu Val
                 110                 115

<210> 6000
<211> 1880
<212> DNA
<213> Homo sapien

<400> 6000
 atgcaacagg acggacttgg agtagggaca aggaacggaa gtgggaaggg 50

 gaggagcgtg cacccctcct ggccttggtg cgcgccgcgc cccctaaggt 100

 actttggaag ggacgcgcgg gccagacgcg cccagacggc cgcgatggcg 150

 ctggccatcc aggtgaccgt gtccaacccc taccacgtgg tgatcctctt 200

 ccagcctgtg accctgccct gtacctacca gatgacctcg acccccacgc 250

 aacccatcgt catctggaag tacaagtctt tctgccggga ccgcatcgcc 300

 gatgccttct ccccggccag cgtcgacaac cagctcaatg cccagctggc 350

 agccgggaac ccaggctaca acccctacgt tgagtgccag gacagcgtgc 400

 gcaccgtcag ggtcgtggcc accaagcagg gcaacgctgt gaccctggga 450

 gattactacc agggccggag gattaccatc accggaaatg ctgacctgac 500

 ctttgaccag acggcgtggg gggacagtgg tgtgtattac tgctccgtgg 550

 tctcagccca ggacctccag gggaacaatg aggcctacgc agagctcatc 600

 gtccttggga ggacctcagg ggtggctgag ctcttacctg gttttcaggc 650

 ggggcccata gaagactggc tcttcgtggt tgtggtatgc ctggctgcct 700

 tcctcatctt cctcctcctg ggcatctgct ggtgccagtg ctgcccgcac 750

 acttgctgct gctacgtcag gtgcccctgc tgcccagaca agtgctgctg 800

 ccccgaggcc ctgtatgccg ccggcaaagc agccacctca ggtgttccca 850

 gcatttatgc ccccagcacc tatgcccacc tgtctcccgc caagacccca 900

 cccccaccag ctatgattcc catgggccct gcctacaacg ggtaccctgg 950

 aggataccct ggagacgttg acaggagtag ctcagtccgc agtggctaca 1000

 ggattcaggc cagccagcag gacgactcca tgcgggtcct gtactacatg 1050

 gagaaggagc tggccaactt cgacccttct cgacctggcc cccccagtgg 1100

 ccgtgtggag cgggccatga gtgaagtcac ctccctccac gaggacgact 1150

 ggcgatctcg gccttcccgg ggccctgccc tcaccccgat ccgggatgag 1200

 gagtggggtg gccactcccc ccggagtccc aggggatggg accaggagcc 1250

 cgccagggag caggcaggcg ggggctggcg ggccaggcgg ccccgggccc 1300

 gctccgtgga cgccctggac gacctcaccc cgccgagcac cgccgagtca 1350

 gggagcaggt ctcccacgag taatggtggg agaagccggg cctacatgcc 1400

 cccgcggagc cgcagccggg acgacctcta tgaccaagac gactcgaggg 1450

 acttcccacg ctcccgggac ccccactacg acgacttcag gtctcgggag 1500

 cgccctcctg ccgaccccag gtcccaccac caccgtaccc gggaccctcg 1550

 ggacaacggc tccaggtccg gggacctccc ctatgatggg cggctactgg 1600

 aggaggctgt gaggaagaag gggtcggagg agaggaggag accccacaag 1650

 gaggaggagg aagaggccta ctacccgccc gcgccgcccc cgtactcgga 1700

 gaccgactcg caggcgtccc gagagcgcag gctcaagaag aacttggccc 1750

 tgagtcggga aagtttagtc gtctgatctg acgttttcta cgtagctttt 1800

 gtattttttt ttttaatttg aaggaacact gatgaagccc tgccataccc 1850

 ctcccgagtc taataaaacg tataatcaca 1880

<210> 6001
<211> 591
<212> PRT
<213> Homo sapien

<400> 6001
 Met Gln Gln Asp Gly Leu Gly Val Gly Thr Arg Asn Gly Ser Gly
   1               5                  10                  15

 Lys Gly Arg Ser Val His Pro Ser Trp Pro Trp Cys Ala Pro Arg
                  20                  25                  30

 Pro Leu Arg Tyr Phe Gly Arg Asp Ala Arg Ala Arg Arg Ala Gln
                  35                  40                  45

 Thr Ala Ala Met Ala Leu Ala Ile Gln Val Thr Val Ser Asn Pro
                  50                  55                  60

 Tyr His Val Val Ile Leu Phe Gln Pro Val Thr Leu Pro Cys Thr
                  65                  70                  75

 Tyr Gln Met Thr Ser Thr Pro Thr Gln Pro Ile Val Ile Trp Lys
                  80                  85                  90

 Tyr Lys Ser Phe Cys Arg Asp Arg Ile Ala Asp Ala Phe Ser Pro
                  95                 100                 105

 Ala Ser Val Asp Asn Gln Leu Asn Ala Gln Leu Ala Ala Gly Asn
                 110                 115                 120

 Pro Gly Tyr Asn Pro Tyr Val Glu Cys Gln Asp Ser Val Arg Thr
                 125                 130                 135

 Val Arg Val Val Ala Thr Lys Gln Gly Asn Ala Val Thr Leu Gly
                 140                 145                 150

 Asp Tyr Tyr Gln Gly Arg Arg Ile Thr Ile Thr Gly Asn Ala Asp
                 155                 160                 165

 Leu Thr Phe Asp Gln Thr Ala Trp Gly Asp Ser Gly Val Tyr Tyr
                 170                 175                 180

 Cys Ser Val Val Ser Ala Gln Asp Leu Gln Gly Asn Asn Glu Ala
                 185                 190                 195

 Tyr Ala Glu Leu Ile Val Leu Gly Arg Thr Ser Gly Val Ala Glu
                 200                 205                 210

 Leu Leu Pro Gly Phe Gln Ala Gly Pro Ile Glu Asp Trp Leu Phe
                 215                 220                 225

 Val Val Val Val Cys Leu Ala Ala Phe Leu Ile Phe Leu Leu Leu
                 230                 235                 240

 Gly Ile Cys Trp Cys Gln Cys Cys Pro His Thr Cys Cys Cys Tyr
                 245                 250                 255

 Val Arg Cys Pro Cys Cys Pro Asp Lys Cys Cys Cys Pro Glu Ala
                 260                 265                 270

 Leu Tyr Ala Ala Gly Lys Ala Ala Thr Ser Gly Val Pro Ser Ile
                 275                 280                 285

 Tyr Ala Pro Ser Thr Tyr Ala His Leu Ser Pro Ala Lys Thr Pro
                 290                 295                 300

 Pro Pro Pro Ala Met Ile Pro Met Gly Pro Ala Tyr Asn Gly Tyr
                 305                 310                 315

 Pro Gly Gly Tyr Pro Gly Asp Val Asp Arg Ser Ser Ser Val Arg
                 320                 325                 330

 Ser Gly Tyr Arg Ile Gln Ala Ser Gln Gln Asp Asp Ser Met Arg
                 335                 340                 345

 Val Leu Tyr Tyr Met Glu Lys Glu Leu Ala Asn Phe Asp Pro Ser
                 350                 355                 360

 Arg Pro Gly Pro Pro Ser Gly Arg Val Glu Arg Ala Met Ser Glu
                 365                 370                 375

 Val Thr Ser Leu His Glu Asp Asp Trp Arg Ser Arg Pro Ser Arg
                 380                 385                 390

 Gly Pro Ala Leu Thr Pro Ile Arg Asp Glu Glu Trp Gly Gly His
                 395                 400                 405

 Ser Pro Arg Ser Pro Arg Gly Trp Asp Gln Glu Pro Ala Arg Glu
                 410                 415                 420

 Gln Ala Gly Gly Gly Trp Arg Ala Arg Arg Pro Arg Ala Arg Ser
                 425                 430                 435

 Val Asp Ala Leu Asp Asp Leu Thr Pro Pro Ser Thr Ala Glu Ser
                 440                 445                 450

 Gly Ser Arg Ser Pro Thr Ser Asn Gly Gly Arg Ser Arg Ala Tyr
                 455                 460                 465

 Met Pro Pro Arg Ser Arg Ser Arg Asp Asp Leu Tyr Asp Gln Asp
                 470                 475                 480

 Asp Ser Arg Asp Phe Pro Arg Ser Arg Asp Pro His Tyr Asp Asp
                 485                 490                 495

 Phe Arg Ser Arg Glu Arg Pro Pro Ala Asp Pro Arg Ser His His
                 500                 505                 510

 His Arg Thr Arg Asp Pro Arg Asp Asn Gly Ser Arg Ser Gly Asp
                 515                 520                 525

 Leu Pro Tyr Asp Gly Arg Leu Leu Glu Glu Ala Val Arg Lys Lys
                 530                 535                 540

 Gly Ser Glu Glu Arg Arg Arg Pro His Lys Glu Glu Glu Glu Glu
                 545                 550                 555

 Ala Tyr Tyr Pro Pro Ala Pro Pro Pro Tyr Ser Glu Thr Asp Ser
                 560                 565                 570

 Gln Ala Ser Arg Glu Arg Arg Leu Lys Lys Asn Leu Ala Leu Ser
                 575                 580                 585

 Arg Glu Ser Leu Val Val
                 590

<210> 6002
<211> 3389
<212> DNA
<213> Homo sapien

<400> 6002
 gtagatgaac aggaagcaac tggaggtaat acctatgatt tgggtaatat 50

 ctctagataa gagtaaaggg acttttcaca taggcagtca cttcacctct 100

 acgagtctca ttttttccaa ctgcacaaat acagattttc gatactttat 150

 ttatgcagtg acatacactg tcattcttgt gccaggtctc atagggaata 200

 tattagccct gtgggtattc tatggttata tgaaagaaac aaaacgagct 250

 gtgatattta tgataaactt agccattgct gacttactac aagttctttc 300

 cttgccactg aggatcttct actacttgaa tcatgactgg ccatttgggc 350

 ctggtctctg catgttctgt ttctacctga agtatgtcaa catgtatgca 400

 agcatctact tcttggtctg catcagtgtg cgacgatttt ggtttctcat 450

 gtaccccttt cgcttccatg actgcaaaca gaaatatgac ctgtacatca 500

 gcattgctgg ctggctgatc atctgccttg cctgtgtact ctttccactc 550

 ctcagaacca gtgatgatac ccctggcaat aggaccaaat gctttgtgga 600

 tcttcctacc aggaatgtca acctggccca gtccgttgtt atgatgacca 650

 ttggcgagtt gattgggttt gtaactccgc ttctgattgt cctatattgt 700

 acctggaaga cggttttatc actgcaagat aaatatccca tggcccaaga 750

 tcttggagag aaacagaaag ccttgaagat gattctaacc tgtgcagggg 800

 tattcctaat ttgctttgca ccttatcatt tcagttttcc tttagatttc 850

 ctggtgaagt ccaatgaaat taaaagctgc ctagccagaa gggtgattct 900

 aatatttcat tctgtggcat tgtgtcttgc tagtctgaat tcatgtcttg 950

 acccagtcat atactacttt tccactaatg agttccgaag acggctttca 1000

 agacaagatt tgcatgacag catccaactc catgcaaaat cctttgtgag 1050

 taaccataca gcttccacca tgacacctga attatgctaa aacaaaaaac 1100

 caaactgaat gtgacctgaa atgcaagtac atcagaacat atctgcaata 1150

 cccaagccac agggaagaac ttgcaaaaca acacagcttt tcagttctgc 1200

 tctatcttac tgctatgggg aattcacttc ttcaaagcag gacctatttg 1250

 gagcattacg atccacgatt attgatgttg acatgtccat gtagtaattt 1300

 ttcttcaagt ctgtaaatct taaaatatca aatttctgtg acatcctata 1350

 aacatatgca ctcaactgta gtcagtactt ttacctgtga acctcaggca 1400

 caaaaagatt attagcttgg agtcaccata aacatttagt tttgttgcaa 1450

 cagatactga gtctttatgt tcagaggaaa tgtaagtgtc tttttatatt 1500

 agtaatcaca gtttacatgc cattttcata tgtttggtta tattttagtg 1550

 ggatagatga tatattaccc tgtgtaaaga aaatgtaaac ataagatcat 1600

 ttttatctct caagtgtgat tactcttcag agtttgaaga ttaaaatagc 1650

 tattttcttc attttgtgtc aacatgaaac atcatttgtc acacctgttc 1700

 acagaatgaa aatctgaact caggcctctg gcatatttaa actaagaaca 1750

 atatacatat ttacatacga caaccctctg tgactggaaa agatgccgtg 1800

 ttgcatctac ctaggacagg tagttgtcaa agtccataca aggtgactca 1850

 attgggctct aggcctagga gaaagcagaa aggtgacaat cacaattctg 1900

 ctctcttaca ctttttctaa agaacacttc tggagatgta tggacccgcc 1950

 tagtagagga agtttttatc atgtttctag agatacattg aggtaatgtt 2000

 gacaggttcc tgcactttct gagcctgtgg aagaagtagt gcactaatga 2050

 atcattaaac ctgggccaga gtgaaaagat gaagcaaagt tgggtaatct 2100

 ttttaaaatt ctcatcacat tgtatttctt actctaatac aaggacactt 2150

 acttagctta gactgccaag ttacttacac aagccagagt aagtctctct 2200

 gccccatcat tgcatacata ttacagtcag tcacatggac cctagaatcc 2250

 acattgattt tttttggtct agctttgccc cagacatacc attctaaagc 2300

 ctacaaagcc tagctcttag cagctgggga aggcaattat ttcacctctt 2350

 gaaaaatgca tagaagatta atttggtcag cctttggcaa ccaatggcca 2400

 atgacttgcc tactacctgt ttggtactat tgtgtgggaa acagacccag 2450

 gatattagtc gtaattaaac cttaggttgt aagtattaga atattttgaa 2500

 acatgtttta gcaaaaagct ctaactttaa gaaagttcta cttaaaatct 2550

 gtgtgctata taatgaagat accttctacg tctcacagaa ggaatgtaga 2600

 acccaatcaa aggctttatc atatttagag gaaaggggtt gttttaggca 2650

 tacagttatg atactaatac attaggggaa aactggtgac atcaaaatga 2700

 attctaatat ctagactgat ggaaagtttt ctaaagtttt ctttggacaa 2750

 gtgttgattt tacacatatg ttgttattaa gataataccc tattagaaaa 2800

 ctgactttgt gctgctagca agtgtatcta tgtgtctcct aactaatcat 2850

 tgtaaggtat atgttttgat gtgttaaata agttttcaat aagtgttaaa 2900

 ctgtatttta aatagggcat ctataactgt gtcttgtctc tttgctttaa 2950

 agtgtctttt gtttgactat aatttagtgt tgcaatagga ttgcaagtaa 3000

 taattttgtg gaattgtgaa ataactgtgg gtacttttaa tgtgagagtc 3050

 ttatctatag tatttgtgct tagtattttc tagattagca tgaattacac 3100

 ttcctaaggt cactttggaa gatgattgat ttgatttaat taacatattg 3150

 atttcacttt gactatattt ttcttaaaga ggaagggaaa tattttcagg 3200

 agatgtttga ccttcttaga tgaatggttg agggtagggc ccatttgtta 3250

 ggcagccatt tacatcattc caaaaaaagg accagtattc agtgttatgc 3300

 tgcttagctg aggacaccct ttttccccag ggcctgccaa tctaacgttg 3350

 tattcaggtg ctctgattta cttaattcac ccttatcca 3389

<210> 6003
<211> 361
<212> PRT
<213> Homo sapien

<400> 6003
 Met Asn Arg Lys Gln Leu Glu Val Ile Pro Met Ile Trp Val Ile
   1               5                  10                  15

 Ser Leu Asp Lys Ser Lys Gly Thr Phe His Ile Gly Ser His Phe
                  20                  25                  30

 Thr Ser Thr Ser Leu Ile Phe Ser Asn Cys Thr Asn Thr Asp Phe
                  35                  40                  45

 Arg Tyr Phe Ile Tyr Ala Val Thr Tyr Thr Val Ile Leu Val Pro
                  50                  55                  60

 Gly Leu Ile Gly Asn Ile Leu Ala Leu Trp Val Phe Tyr Gly Tyr
                  65                  70                  75

 Met Lys Glu Thr Lys Arg Ala Val Ile Phe Met Ile Asn Leu Ala
                  80                  85                  90

 Ile Ala Asp Leu Leu Gln Val Leu Ser Leu Pro Leu Arg Ile Phe
                  95                 100                 105

 Tyr Tyr Leu Asn His Asp Trp Pro Phe Gly Pro Gly Leu Cys Met
                 110                 115                 120

 Phe Cys Phe Tyr Leu Lys Tyr Val Asn Met Tyr Ala Ser Ile Tyr
                 125                 130                 135

 Phe Leu Val Cys Ile Ser Val Arg Arg Phe Trp Phe Leu Met Tyr
                 140                 145                 150

 Pro Phe Arg Phe His Asp Cys Lys Gln Lys Tyr Asp Leu Tyr Ile
                 155                 160                 165

 Ser Ile Ala Gly Trp Leu Ile Ile Cys Leu Ala Cys Val Leu Phe
                 170                 175                 180

 Pro Leu Leu Arg Thr Ser Asp Asp Thr Pro Gly Asn Arg Thr Lys
                 185                 190                 195

 Cys Phe Val Asp Leu Pro Thr Arg Asn Val Asn Leu Ala Gln Ser
                 200                 205                 210

 Val Val Met Met Thr Ile Gly Glu Leu Ile Gly Phe Val Thr Pro
                 215                 220                 225

 Leu Leu Ile Val Leu Tyr Cys Thr Trp Lys Thr Val Leu Ser Leu
                 230                 235                 240

 Gln Asp Lys Tyr Pro Met Ala Gln Asp Leu Gly Glu Lys Gln Lys
                 245                 250                 255

 Ala Leu Lys Met Ile Leu Thr Cys Ala Gly Val Phe Leu Ile Cys
                 260                 265                 270

 Phe Ala Pro Tyr His Phe Ser Phe Pro Leu Asp Phe Leu Val Lys
                 275                 280                 285

 Ser Asn Glu Ile Lys Ser Cys Leu Ala Arg Arg Val Ile Leu Ile
                 290                 295                 300

 Phe His Ser Val Ala Leu Cys Leu Ala Ser Leu Asn Ser Cys Leu
                 305                 310                 315

 Asp Pro Val Ile Tyr Tyr Phe Ser Thr Asn Glu Phe Arg Arg Arg
                 320                 325                 330

 Leu Ser Arg Gln Asp Leu His Asp Ser Ile Gln Leu His Ala Lys
                 335                 340                 345

 Ser Phe Val Ser Asn His Thr Ala Ser Thr Met Thr Pro Glu Leu
                 350                 355                 360

 Cys


<210> 6004
<211> 1696
<212> DNA
<213> Homo sapien

<400> 6004
 agaacagacg tttgaacaga gcaggcttct gaggtctcca aaatgcctgt 50

 cccagcctcc tggccccatc ctcctggtcc tttcctgctt ctgactctac 100

 tgctgggact tacagaagtg gcaggtgagg aggagctaca gatgattcag 150

 cctgagaagc tcctgttggt cacagttgga aagacagcca ctctgcactg 200

 cactgtgacc tccctgcttc ccgtgggacc cgtcctgtgg ttcagaggag 250

 ttggaccagg ccgagaatta atctacaatc aaaaagaagg ccacttcccc 300

 agggtaacaa cagtttcaga cctcacaaag agaaacaaca tggacttttc 350

 catccgcatc agtagcatca ccccagcaga tgtcggcaca tactactgtg 400

 tgaagtttcg aaaagggagc cctgagaacg tggagtttaa gtctggacca 450

 ggcactgaga tggctttggg tgccaaaccc tctgcccccg tggtattggg 500

 ccctgcggcg aggaccacac ctgagcatac agtgagtttc acctgtgagt 550

 cccatggctt ctctcccaga gacatcaccc tgaaatggtt caaaaatggg 600

 aatgagctct cagacttcca gaccaacgtg gaccccacag gacagagtgt 650

 ggcctacagc atccgcagca cagccagggt ggtactggac ccctgggacg 700

 ttcgctctca ggtcatctgc gaggtggccc atgtcacctt gcagggggac 750

 cctcttcgtg ggactgccaa cttgtctgag gccatccgag ttccacccac 800

 cttggaggtt actcaacagc ccatgagggc ggggaaccag gtaaacgtca 850

 cctgccaggt gaggaagttc tacccccaga gcctacagct gacctggttg 900

 gagaatggaa acgtgtgcca gagagaaaca gcctcgaccc ttacagagaa 950

 caaggatggt acctacaact ggacaagctg gttcctggtg aacatatctg 1000

 accaaaggga tgatgtggtc ctcacctgcc aggtgaagca tgatgggcag 1050

 ctggcggtca gcaaacgcct tgccctggag gtcacagtcc accagaagga 1100

 ccagagctca gatgctaccc ctggcccggc atcatctctt actgcgctgc 1150

 tcctcatagc tgtcctcctg ggccccatct atgtcccctg gaagcagaag 1200

 acctgactct ccttccttcc tcccctgcca cgtgggaccc tcatctctgc 1250

 tgcctccttc ctttcctgag aggctcagct tgagagaatg agccagtgag 1300

 aagcttctct agacttggct ccaaacatct cccctcccaa gacatctgcc 1350

 tgcccacagg ctcctgttgc tccttcacac agacctggat gccccagagc 1400

 aaggtcttca ttcatggtcc tgagcagggg ccatgggatt gggctctggg 1450

 cactgactta acggcacctc cctagaaggc gagaaacatg ccaaatctaa 1500

 acacaccagg actcccatcc atcgccttga gactgaccgt aaaccacaga 1550

 cgctctccag gttctcaaga gttatcctgc cttccagatt cctgcctatc 1600

 ccaactcccc agccttgttg aggttctcta ttgcctcttg aatacaaatg 1650

 cactcccaaa gtggttttaa gaaaataaaa agattatcct tccaaa 1696

<210> 6005
<211> 354
<212> PRT
<213> Homo sapien

<400> 6005
 Met Ile Gln Pro Glu Lys Leu Leu Leu Val Thr Val Gly Lys Thr
   1               5                  10                  15

 Ala Thr Leu His Cys Thr Val Thr Ser Leu Leu Pro Val Gly Pro
                  20                  25                  30

 Val Leu Trp Phe Arg Gly Val Gly Pro Gly Arg Glu Leu Ile Tyr
                  35                  40                  45

 Asn Gln Lys Glu Gly His Phe Pro Arg Val Thr Thr Val Ser Asp
                  50                  55                  60

 Leu Thr Lys Arg Asn Asn Met Asp Phe Ser Ile Arg Ile Ser Ser
                  65                  70                  75

 Ile Thr Pro Ala Asp Val Gly Thr Tyr Tyr Cys Val Lys Phe Arg
                  80                  85                  90

 Lys Gly Ser Pro Glu Asn Val Glu Phe Lys Ser Gly Pro Gly Thr
                  95                 100                 105

 Glu Met Ala Leu Gly Ala Lys Pro Ser Ala Pro Val Val Leu Gly
                 110                 115                 120

 Pro Ala Ala Arg Thr Thr Pro Glu His Thr Val Ser Phe Thr Cys
                 125                 130                 135

 Glu Ser His Gly Phe Ser Pro Arg Asp Ile Thr Leu Lys Trp Phe
                 140                 145                 150

 Lys Asn Gly Asn Glu Leu Ser Asp Phe Gln Thr Asn Val Asp Pro
                 155                 160                 165

 Thr Gly Gln Ser Val Ala Tyr Ser Ile Arg Ser Thr Ala Arg Val
                 170                 175                 180

 Val Leu Asp Pro Trp Asp Val Arg Ser Gln Val Ile Cys Glu Val
                 185                 190                 195

 Ala His Val Thr Leu Gln Gly Asp Pro Leu Arg Gly Thr Ala Asn
                 200                 205                 210

 Leu Ser Glu Ala Ile Arg Val Pro Pro Thr Leu Glu Val Thr Gln
                 215                 220                 225

 Gln Pro Met Arg Ala Gly Asn Gln Val Asn Val Thr Cys Gln Val
                 230                 235                 240

 Arg Lys Phe Tyr Pro Gln Ser Leu Gln Leu Thr Trp Leu Glu Asn
                 245                 250                 255

 Gly Asn Val Cys Gln Arg Glu Thr Ala Ser Thr Leu Thr Glu Asn
                 260                 265                 270

 Lys Asp Gly Thr Tyr Asn Trp Thr Ser Trp Phe Leu Val Asn Ile
                 275                 280                 285

 Ser Asp Gln Arg Asp Asp Val Val Leu Thr Cys Gln Val Lys His
                 290                 295                 300

 Asp Gly Gln Leu Ala Val Ser Lys Arg Leu Ala Leu Glu Val Thr
                 305                 310                 315

 Val His Gln Lys Asp Gln Ser Ser Asp Ala Thr Pro Gly Pro Ala
                 320                 325                 330

 Ser Ser Leu Thr Ala Leu Leu Leu Ile Ala Val Leu Leu Gly Pro
                 335                 340                 345

 Ile Tyr Val Pro Trp Lys Gln Lys Thr
                 350

<210> 6006
<211> 1812
<212> DNA
<213> Homo sapien

<400> 6006
 gttcccaatc agtttccagc caacaccagg gtgtcctagt ccgcagaggt 50

 gtgggggaca cactccataa tctctacttt tctttttgtg cagctgagtc 100

 atggagcttt cagccccagc acatggctcc tccttaactg cgtctgctca 150

 acctccctca gccctgtgaa cagcatcccc gcacacagac gcagagcagg 200

 actctctctg ctgccacttc accttcctga gagaggacca gcggccagag 250

 cctcagtgac tgccaccctg gaggacaggg cacaacaacc gtttctggag 300

 agaatgggag gattccagag gggcaaatat ggaactatgg ctgaaggtag 350

 atcagaagat aacttgtctg caacaccacc ggcattgagg attatcctag 400

 tgggcaaaac aggctgcggg aaaagtgcca cagggaacag catccttggc 450

 cagcccgtgt ttgagtccaa gctgagggcc cagtcagtga ccaggacgtg 500

 ccaggtgaaa acaggaacat ggaacgggag gaaagtcctg gtggttgaca 550

 cgccctccat ctttgagtca caggccgata cccaagagct gtacaagaac 600

 atcggggact gctacctgct ctctgccccg gggccccacg tcctgcttct 650

 ggtgatccag ctggggcgtt tcactgctca ggacacagtg gccatcagga 700

 aggtgaaaga ggtctttggg acaggggcca tgagacatgt ggtcatcctc 750

 ttcacccaca aagaggactt agggggccag gccctggatg actatgtagc 800

 aaacacggac aactgcagcc tgaaagacct ggtgcgggag tgtgagagaa 850

 ggtactgtgc cttcaacaac tggggctctg tggaggagca gaggcagcag 900

 caggcagagc tcctggctgt gattgagagg ctggggaggg agcgagaggg 950

 ctccttccac agcaatgacc tcttcttgga tgcccagctg ctccaaagaa 1000

 ctggagctgg ggcctgccag gaagactaca ggcagtacca ggccaaagtg 1050

 gaatggcagg tggagaagca caagcaagag ctgagggaga acgagagtaa 1100

 ctgggcatac aaggcgctcc tcagagtcaa acacttgatg cttttgcatt 1150

 atgagatttt tgtttttcta ttgttgtgca gcatactttt tttcattatt 1200

 tttctgttca tctttcatta catttaaatc tctggaccct ggagcacttc 1250

 taatgtatca ccccatggag tcattgttct aataatcacc aattcagact 1300

 cagatcctcg tggtctatgg agcatgctgc ttgctgtctg tgcagctccc 1350

 atttcccctt cttcctgata gacttggagc tgtgtgcctc cactccaagg 1400

 ctgcctgcct gctgtaaaca ctattccact ctgtctgcca acaactgctt 1450

 caggaatggg cctgagatcc catgcaggtc cctgagaagt gagtaaaagt 1500

 ccgcagaggt ggggatggaa gatctctcct tagatagaac ctgtcttcct 1550

 ccctggcatt gtggggtctg ggcgtgacac tgggactctc agcagctttg 1600

 tgctgccaac ctgagattga aggcagtgcc tcagagcagc acagagagtt 1650

 ggggccccct gagccctgag ccaccagccc tgcagcctgc cctatctccg 1700

 catttccagt tgtattagcc aatagatttc ctacttattt aagctatttg 1750

 agctccgggt ctcttctacc tgcattctaa aacattcaaa gtaataaaaa 1800

 tttctccaca tt 1812

<210> 6007
<211> 307
<212> PRT
<213> Homo sapien

<400> 6007
 Met Gly Gly Phe Gln Arg Gly Lys Tyr Gly Thr Met Ala Glu Gly
   1               5                  10                  15

 Arg Ser Glu Asp Asn Leu Ser Ala Thr Pro Pro Ala Leu Arg Ile
                  20                  25                  30

 Ile Leu Val Gly Lys Thr Gly Cys Gly Lys Ser Ala Thr Gly Asn
                  35                  40                  45

 Ser Ile Leu Gly Gln Pro Val Phe Glu Ser Lys Leu Arg Ala Gln
                  50                  55                  60

 Ser Val Thr Arg Thr Cys Gln Val Lys Thr Gly Thr Trp Asn Gly
                  65                  70                  75

 Arg Lys Val Leu Val Val Asp Thr Pro Ser Ile Phe Glu Ser Gln
                  80                  85                  90

 Ala Asp Thr Gln Glu Leu Tyr Lys Asn Ile Gly Asp Cys Tyr Leu
                  95                 100                 105

 Leu Ser Ala Pro Gly Pro His Val Leu Leu Leu Val Ile Gln Leu
                 110                 115                 120

 Gly Arg Phe Thr Ala Gln Asp Thr Val Ala Ile Arg Lys Val Lys
                 125                 130                 135

 Glu Val Phe Gly Thr Gly Ala Met Arg His Val Val Ile Leu Phe
                 140                 145                 150

 Thr His Lys Glu Asp Leu Gly Gly Gln Ala Leu Asp Asp Tyr Val
                 155                 160                 165

 Ala Asn Thr Asp Asn Cys Ser Leu Lys Asp Leu Val Arg Glu Cys
                 170                 175                 180

 Glu Arg Arg Tyr Cys Ala Phe Asn Asn Trp Gly Ser Val Glu Glu
                 185                 190                 195

 Gln Arg Gln Gln Gln Ala Glu Leu Leu Ala Val Ile Glu Arg Leu
                 200                 205                 210

 Gly Arg Glu Arg Glu Gly Ser Phe His Ser Asn Asp Leu Phe Leu
                 215                 220                 225

 Asp Ala Gln Leu Leu Gln Arg Thr Gly Ala Gly Ala Cys Gln Glu
                 230                 235                 240

 Asp Tyr Arg Gln Tyr Gln Ala Lys Val Glu Trp Gln Val Glu Lys
                 245                 250                 255

 His Lys Gln Glu Leu Arg Glu Asn Glu Ser Asn Trp Ala Tyr Lys
                 260                 265                 270

 Ala Leu Leu Arg Val Lys His Leu Met Leu Leu His Tyr Glu Ile
                 275                 280                 285

 Phe Val Phe Leu Leu Leu Cys Ser Ile Leu Phe Phe Ile Ile Phe
                 290                 295                 300

 Leu Phe Ile Phe His Tyr Ile
                 305

<210> 6008
<211> 446
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 180-181
<223> Unknown base

<400> 6008
 gattgccatt aaagcagaaa ttataaggtt gcaacaatat ttgtttctaa 50

 tcactggctt tctcaagagt atggattgac atattgtgtt atgaatgcac 100

 atctctcaga tgtgttgaag catccattgc atccattttt tattattttc 150

 ttagttttgt tcttggacaa atttaaacan nttaaaagat tattcaagat 200

 gaatttaaaa gtcaaccctt cacacagttt ccctactgta tgtagaatcc 250

 aggtgctgaa accaagtgtt tcttttccca tgctctttgt taaactccaa 300

 ttatagataa tttttccagt cttaagctct gtccaccttc aagtcaattc 350

 ataaccaagt ttttgaacgc tgctatgaat tgcactgtga aaagcactct 400

 tccctctcag ttttcgttca tcctgagcca gaatcaaaaa aaaaaa 446

<210> 6009
<211> 71
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 30-31
<223> unknown amino acid

<220>
<221> Unsure
<222> 180-181
<223> Unknown amino acid

<400> 6009
 Met Asn Ala His Leu Ser Asp Val Leu Lys His Pro Leu His Pro
   1               5                  10                  15

 Phe Phe Ile Ile Phe Leu Val Leu Phe Leu Asp Lys Phe Lys Xaa
                  20                  25                  30

 Xaa Lys Arg Leu Phe Lys Met Asn Leu Lys Val Asn Pro Ser His
                  35                  40                  45

 Ser Phe Pro Thr Val Cys Arg Ile Gln Val Leu Lys Pro Ser Val
                  50                  55                  60

 Ser Phe Pro Met Leu Phe Val Lys Leu Gln Leu
                  65                  70

<210> 6010
<211> 2119
<212> DNA
<213> Homo sapien

<400> 6010
 ggcacgagta ggggtggcgg gtcagtgctg ctcgggggct tctccatcca 50

 ggtccctgga gttcctggtc cctggagctc cgcacttggc gcgcaacctg 100

 cgtgaggcag cgcgactctg gcgactggcc ggccatgcct tcccgggctg 150

 aggactatga agtgttgtac accattggca caggctccta cggccgctgc 200

 cagaagatcc ggaggaagag tgatggcaag atattagttt ggaaagaact 250

 tgactatggc tccatgacag aagctgagaa acagatgctt gtttctgaag 300

 tgaatttgct tcgtgaactg aaacatccaa acatcgttcg ttactatgat 350

 cggattattg accggaccaa tacaacactg tacattgtaa tggaatattg 400

 tgaaggaggg gatctggcta gtgtaattac aaagggaacc aaggaaaggc 450

 aatacttaga tgaagagttt gttcttcgag tgatgactca gttgactctg 500

 gccctgaagg aatgccacag acgaagtgat ggtggtcata ccgtattgca 550

 tcgggatctt aaaccagcca atgttttcct ggatggcaag caaaacgtca 600

 agcttggaga ctttgggcta gctagaatat taaaccatga cacgagtttt 650

 gcaaaaacat ttgttggcac accttattac atgtctcctg aacaaatgaa 700

 tcgcatgtcc tacaatgaga aatcagatat ctggtcattg ggctgcttgc 750

 tgtatgagtt atgtgcatta atgcctccat ttacagcttt tagccagaaa 800

 gaactcgctg ggaaaatcag agaaggcaaa ttcaggcgaa ttccataccg 850

 ttactctgat gaattgaatg aaattattac gaggatgtta aacttaaagg 900

 attaccatcg accttctgtt gaagaaattc ttgagaaccc tttaatagca 950

 gatttggttg cagacgagca aagaagaaat cttgagagaa gagggcgaca 1000

 attaggagag ccagaaaaat cgcaggattc cagccctgta ttgagtgagc 1050

 tgaaactgaa ggaaattcag ttacaggagc gagagcgagc tctcaaagca 1100

 agagaagaaa gattggagca gaaagaacag gagctttgtg ttcgtgagag 1150

 actagcagag gacaaactgg ctagagcaga aaatctgttg aagaactaca 1200

 gcttgctaaa ggaacggaag ttcctgtctc tggcaagtaa tccagaactt 1250

 cttaatcttc catcctcagt aattaagaag aaagttcatt tcagtgggga 1300

 aagtaaagag aacatcatga ggagtgagaa ttctgagagt cagctcacat 1350

 ctaagtccaa gtgcaaggac ctgaagaaaa ggcttcacgc tgcccagctg 1400

 cgggctcaag ccctgtcaga tattgagaaa aattaccaac tgaaaagcag 1450

 acagatcctg ggcatgcgct agccaggtag agagacacag agctgtgtac 1500

 aggatgtaat attaccaacc tttaaagact gatattcaaa tgctgtagtg 1550

 ttgaatactt ggccccatga gccatgcctt tctgtatagt acacatgata 1600

 tttcggaatt ggttttactg ttcttcagca actattgtac aaaatgttca 1650

 catttaattt ttctttcttc ttttaagaac atattataaa aagaatactt 1700

 tcttggttgg gcttttaatc ctgtgtgtga ttactagtag gaacatgaga 1750

 tgtgacattc taaatcttgg gagaaaaaat aatattagga aaaaaatatt 1800

 tatgcaggaa gagtagcact cactgaatag ttttaaatga ctgagtggta 1850

 tgcttacaat tgtcatgtct agatttaaat tttaagtctg agattttaaa 1900

 tgtttttgag cttagaaaac ccagttagat gcaatttggt cattaatacc 1950

 atgacatctt gcttataaat attccattgc tctgtagttc aaatctgtta 2000

 gctttgtgaa aattcatcac tgtgatgttt gtattctttt tttttttctg 2050

 tttaacagaa tatgagctgt ctgtcattta cctacttctt tcccactaaa 2100

 taaaagaatt cttcagtta 2119

<210> 6011
<211> 445
<212> PRT
<213> Homo sapien

<400> 6011
 Met Pro Ser Arg Ala Glu Asp Tyr Glu Val Leu Tyr Thr Ile Gly
   1               5                  10                  15

 Thr Gly Ser Tyr Gly Arg Cys Gln Lys Ile Arg Arg Lys Ser Asp
                  20                  25                  30

 Gly Lys Ile Leu Val Trp Lys Glu Leu Asp Tyr Gly Ser Met Thr
                  35                  40                  45

 Glu Ala Glu Lys Gln Met Leu Val Ser Glu Val Asn Leu Leu Arg
                  50                  55                  60

 Glu Leu Lys His Pro Asn Ile Val Arg Tyr Tyr Asp Arg Ile Ile
                  65                  70                  75

 Asp Arg Thr Asn Thr Thr Leu Tyr Ile Val Met Glu Tyr Cys Glu
                  80                  85                  90

 Gly Gly Asp Leu Ala Ser Val Ile Thr Lys Gly Thr Lys Glu Arg
                  95                 100                 105

 Gln Tyr Leu Asp Glu Glu Phe Val Leu Arg Val Met Thr Gln Leu
                 110                 115                 120

 Thr Leu Ala Leu Lys Glu Cys His Arg Arg Ser Asp Gly Gly His
                 125                 130                 135

 Thr Val Leu His Arg Asp Leu Lys Pro Ala Asn Val Phe Leu Asp
                 140                 145                 150

 Gly Lys Gln Asn Val Lys Leu Gly Asp Phe Gly Leu Ala Arg Ile
                 155                 160                 165

 Leu Asn His Asp Thr Ser Phe Ala Lys Thr Phe Val Gly Thr Pro
                 170                 175                 180

 Tyr Tyr Met Ser Pro Glu Gln Met Asn Arg Met Ser Tyr Asn Glu
                 185                 190                 195

 Lys Ser Asp Ile Trp Ser Leu Gly Cys Leu Leu Tyr Glu Leu Cys
                 200                 205                 210

 Ala Leu Met Pro Pro Phe Thr Ala Phe Ser Gln Lys Glu Leu Ala
                 215                 220                 225

 Gly Lys Ile Arg Glu Gly Lys Phe Arg Arg Ile Pro Tyr Arg Tyr
                 230                 235                 240

 Ser Asp Glu Leu Asn Glu Ile Ile Thr Arg Met Leu Asn Leu Lys
                 245                 250                 255

 Asp Tyr His Arg Pro Ser Val Glu Glu Ile Leu Glu Asn Pro Leu
                 260                 265                 270

 Ile Ala Asp Leu Val Ala Asp Glu Gln Arg Arg Asn Leu Glu Arg
                 275                 280                 285

 Arg Gly Arg Gln Leu Gly Glu Pro Glu Lys Ser Gln Asp Ser Ser
                 290                 295                 300

 Pro Val Leu Ser Glu Leu Lys Leu Lys Glu Ile Gln Leu Gln Glu
                 305                 310                 315

 Arg Glu Arg Ala Leu Lys Ala Arg Glu Glu Arg Leu Glu Gln Lys
                 320                 325                 330

 Glu Gln Glu Leu Cys Val Arg Glu Arg Leu Ala Glu Asp Lys Leu
                 335                 340                 345

 Ala Arg Ala Glu Asn Leu Leu Lys Asn Tyr Ser Leu Leu Lys Glu
                 350                 355                 360

 Arg Lys Phe Leu Ser Leu Ala Ser Asn Pro Glu Leu Leu Asn Leu
                 365                 370                 375

 Pro Ser Ser Val Ile Lys Lys Lys Val His Phe Ser Gly Glu Ser
                 380                 385                 390

 Lys Glu Asn Ile Met Arg Ser Glu Asn Ser Glu Ser Gln Leu Thr
                 395                 400                 405

 Ser Lys Ser Lys Cys Lys Asp Leu Lys Lys Arg Leu His Ala Ala
                 410                 415                 420

 Gln Leu Arg Ala Gln Ala Leu Ser Asp Ile Glu Lys Asn Tyr Gln
                 425                 430                 435

 Leu Lys Ser Arg Gln Ile Leu Gly Met Arg
                 440                 445

<210> 6012
<211> 3780
<212> DNA
<213> Homo sapien

<400> 6012
 tactggacaa acatttcctc caaggacaca gctctctgcc tccatgtcac 50

 cacctttgaa ggactgactg attccctcgg ctggtgccag tgcctgctcc 100

 tgccatgggg cccgcgggga gcctgctggg cagcggacag atgcagatca 150

 ccctgtgggg aagtctggca gctgtcgcca ttttcttcgt catcaccttc 200

 ctcatcttcc cgtgctctag ttgtgacagg gaaaagaagc cgcgacagca 250

 tagtggggac catgagaacc tgatgaacgt gccttcagac aaggagatgt 300

 tcagccgttc agttactagc ctggcaacag atgctcctgc cagcagtgag 350

 cagaatgggg cactcaccaa tggggacatt ctttcagagg acagtactct 400

 gacctgcatg cagcattacg aggaagtcca gacatcggcc tcggatctgc 450

 tggattccca ggacagcaca gggaaaccaa aatgtcatca gagtcgggag 500

 ctgcccagaa tccctcccga gagcgcagtg gataccatgc tcacggcgag 550

 aagtgtggac ggggaccagg ggctggggat ggaagggccc tatgaagtgc 600

 tcaaggacag ctcctcccaa gaaaacatgg tggaggactg cttgtatgaa 650

 actgtgaagg agatcaagga ggtggctgca gctgcacacc tggagaaagg 700

 ccacagtggc aaggcaaaat ctacttctgc ctcgaaagag ctcccagggc 750

 cccagactga aggcaaagct gagtttgctg aatatgcctc ggtggacaga 800

 aacaaaaaat gtcgtcaaag tgttaatgta gagagtatcc ttggaaattc 850

 atgtgatcca gaagaggagg ccccaccacc tgtccctgtt aagcttctgg 900

 acgagaatga aaaccttcag gagaaggaag ggggagaggc ggaagagagt 950

 gccacagaca cgaccagtga aactaacaag agatttagct cattgtcata 1000

 caagtctcgg gaagaagacc ccactctcac agaagaagag atctcagcta 1050

 tgtactcatc agtaaataaa cctggacagt tagtgaataa atcggggcag 1100

 tcgcttacag ttccggagtc cacctacacc tccattcaag gggacccaca 1150

 gaggtcaccc tcctcctgta atgatctcta tgctactgtt aaagacttcg 1200

 aaaaaactcc aaacagcaca cttccaccag cagggaggcc cagcgaggag 1250

 ccagagcctg attatgaagc gatacagact ctcaacagag aggaagaaaa 1300

 ggccaccctg gggaccaatg gccaccacgg tctcgtccca aaggagaacg 1350

 actacgagag cataagtgac ttgcagcaag gcagagatat taccaggctc 1400

 tagcaaccca gaagacaacc ctgggtagcc tgtgatcagt gtctggagac 1450

 gtttcttctg tggaagagaa gaagtgacac aaacctatac ttcatatgct 1500

 gctttagtca cctgaagatg gttggagagg ccctgtcgac tgttctccca 1550

 gttgttcagt ttctgagaca gagaggtacg gactaggctg cacctgagtg 1600

 tgcccctgcc tgccagatgg acaggtacac ccaagcacat ctccctgctg 1650

 caccctcacc acccacaaaa gatcccagct gtcagtggtc tcatctcatt 1700

 agtgaggaaa gccaagctgt atggaaaagc tgcactcacc aaggaccaca 1750

 atgcccccgg cctaaagtac tgccattcag aaaagcaggt ttttcttcct 1800

 ctctttcctt ttctctgtct gctactgact ttaaggcttt ttcccccttg 1850

 aaatgtccag attcctgtgg ttcatcccaa ggaaattttc acacaaagct 1900

 tggcctttgc cctcaatata ggtgttttag gatggtgaca aaccatggct 1950

 gctgctttct gcccagctcg ccagtcctcc ccaaagagtt gcgcatcagc 2000

 acctggggat ctggaccctg cgggtgaagg gatggggagg gacgtccctg 2050

 gagtctcttc tgtctttgtt ccttcttatt ttggcattcg atatcagcag 2100

 cctctcccca aagtacttga agtcagtttt agatgcttta ttttattttt 2150

 ctagtcaaaa acgtgtttcc cccagtgttt gaaaactcgt ccgaatcttt 2200

 tcagtatttt ccatgagtat tgtggtactt ctagacttgt ttaagcccag 2250

 aactcattcc ttcaaaacag agagccttaa tctttatgtt gggacacaga 2300

 ccacatattt ggacggcagc catgcatcca tcgctgaagg gctgtggaca 2350

 tgaatgtgta tttcccatgg tctccgctgc ccacaccaac agtgtggcat 2400

 ctcataagtt aactgctacc ctaaggtaat ctaagattaa aatgtaaaca 2450

 tttatttttg ttatgtaagt ttataagatg ttttatgttc aatgcctaat 2500

 ttctcaaaag tgccagaaaa aaatgtatat tagctatttt gattttatgt 2550

 acaatgattt atactctcct tttgaaaaga taccataaag cacataagct 2600

 agatcactac aaggagctgt tatctttttt ctaatcaagt gtttaaaaca 2650

 ctgatggttt ttaaagactc acctttttaa atggtacttg gagctcctga 2700

 ttcaaattac ctagaccccc tagagaaata aatggaatat acataaataa 2750

 tcattttcag tggtttatgg tgggcaatat tgcaatattt gaaatggtaa 2800

 aaatggaaag aagaacaaaa tatgatgaga ggtggctgtg aattataaac 2850

 ctcataaaag tgtcataatt ccattaaggt ttaattatat tttttcagaa 2900

 aacagtgatg aattctgtag tccagtgctt gccaatgcaa attgcctatt 2950

 ggaatcttct tcctatattt tacaaacatc agtggctgaa atagctcaga 3000

 gtaagagctc agcctggttt gaatttaatc atctctttag atcttataag 3050

 gccagcatta ggaaacttgt tcacttttca ttttcaaagg agcctagttg 3100

 aagtgctatt atgagtgtgg gctatggaaa gacagctttt cctacactga 3150

 taaagaaaaa aaatgaggaa attatttcat ccccttgtga catctgtgac 3200

 tttttggatt taataatctt gctgtttttc ctctttatga caaagaatat 3250

 aattgggagg atgaagtgtc ttaaaaattg tagagaccag ctcactggaa 3300

 tgtttttcca tccctgtatt catggcttga ctttgtgact gctctacact 3350

 gcatgtctga cattgcagag tgagctatgt tgaggtaaac tggttggttg 3400

 tcattatttt gcaatcagcc tggtctctcc catgaagatg tcgtgtgcat 3450

 aagcacaatc atcactgatt agaagatcac agcagaatac ccttggatta 3500

 gagagaagtt cgtaccttgc atttctctga attctagtct ctcataagca 3550

 ctgctttgct ggatgatttt cactgctttg tgttaatgac tttgagcgat 3600

 ctctcacatg atggggttct ttagtacatg gtaacagcca tgtcatctta 3650

 cacacctagc attgtgaatg ctgtagtgac atcctttata ggcaccttac 3700

 agctcaaaac ttttgtttca tttcatgcct tacttatcaa aaaggcagga 3750

 aagtaggtat gatctctaaa gtaaaaaaaa 3780

<210> 6013
<211> 432
<212> PRT
<213> Homo sapien

<400> 6013
 Met Gly Pro Ala Gly Ser Leu Leu Gly Ser Gly Gln Met Gln Ile
   1               5                  10                  15

 Thr Leu Trp Gly Ser Leu Ala Ala Val Ala Ile Phe Phe Val Ile
                  20                  25                  30

 Thr Phe Leu Ile Phe Pro Cys Ser Ser Cys Asp Arg Glu Lys Lys
                  35                  40                  45

 Pro Arg Gln His Ser Gly Asp His Glu Asn Leu Met Asn Val Pro
                  50                  55                  60

 Ser Asp Lys Glu Met Phe Ser Arg Ser Val Thr Ser Leu Ala Thr
                  65                  70                  75

 Asp Ala Pro Ala Ser Ser Glu Gln Asn Gly Ala Leu Thr Asn Gly
                  80                  85                  90

 Asp Ile Leu Ser Glu Asp Ser Thr Leu Thr Cys Met Gln His Tyr
                  95                 100                 105

 Glu Glu Val Gln Thr Ser Ala Ser Asp Leu Leu Asp Ser Gln Asp
                 110                 115                 120

 Ser Thr Gly Lys Pro Lys Cys His Gln Ser Arg Glu Leu Pro Arg
                 125                 130                 135

 Ile Pro Pro Glu Ser Ala Val Asp Thr Met Leu Thr Ala Arg Ser
                 140                 145                 150

 Val Asp Gly Asp Gln Gly Leu Gly Met Glu Gly Pro Tyr Glu Val
                 155                 160                 165

 Leu Lys Asp Ser Ser Ser Gln Glu Asn Met Val Glu Asp Cys Leu
                 170                 175                 180

 Tyr Glu Thr Val Lys Glu Ile Lys Glu Val Ala Ala Ala Ala His
                 185                 190                 195

 Leu Glu Lys Gly His Ser Gly Lys Ala Lys Ser Thr Ser Ala Ser
                 200                 205                 210

 Lys Glu Leu Pro Gly Pro Gln Thr Glu Gly Lys Ala Glu Phe Ala
                 215                 220                 225

 Glu Tyr Ala Ser Val Asp Arg Asn Lys Lys Cys Arg Gln Ser Val
                 230                 235                 240

 Asn Val Glu Ser Ile Leu Gly Asn Ser Cys Asp Pro Glu Glu Glu
                 245                 250                 255

 Ala Pro Pro Pro Val Pro Val Lys Leu Leu Asp Glu Asn Glu Asn
                 260                 265                 270

 Leu Gln Glu Lys Glu Gly Gly Glu Ala Glu Glu Ser Ala Thr Asp
                 275                 280                 285

 Thr Thr Ser Glu Thr Asn Lys Arg Phe Ser Ser Leu Ser Tyr Lys
                 290                 295                 300

 Ser Arg Glu Glu Asp Pro Thr Leu Thr Glu Glu Glu Ile Ser Ala
                 305                 310                 315

 Met Tyr Ser Ser Val Asn Lys Pro Gly Gln Leu Val Asn Lys Ser
                 320                 325                 330

 Gly Gln Ser Leu Thr Val Pro Glu Ser Thr Tyr Thr Ser Ile Gln
                 335                 340                 345

 Gly Asp Pro Gln Arg Ser Pro Ser Ser Cys Asn Asp Leu Tyr Ala
                 350                 355                 360

 Thr Val Lys Asp Phe Glu Lys Thr Pro Asn Ser Thr Leu Pro Pro
                 365                 370                 375

 Ala Gly Arg Pro Ser Glu Glu Pro Glu Pro Asp Tyr Glu Ala Ile
                 380                 385                 390

 Gln Thr Leu Asn Arg Glu Glu Glu Lys Ala Thr Leu Gly Thr Asn
                 395                 400                 405

 Gly His His Gly Leu Val Pro Lys Glu Asn Asp Tyr Glu Ser Ile
                 410                 415                 420

 Ser Asp Leu Gln Gln Gly Arg Asp Ile Thr Arg Leu
                 425                 430

<210> 6014
<211> 1074
<212> DNA
<213> Homo sapien

<400> 6014
 ctcggggagt ggttgtctcc ctttcctgga gtcatttgtg ggagttaggg 50

 tcttatcctg atctttcctc gtcccccgct cccccgtcct ccgaggtggc 100

 agctgcgtag aagtctggaa cgttttttct tagagttcca gaattgtgac 150

 tgaagtgtac ccagagacac aaagaaatac agaagtccag aatgatcaaa 200

 tgagatcact acccaatgaa atgataggcc gaggagccag aaattgtcct 250

 actacctgct ttccaggtcc agattccacg agagccttct gggctcccac 300

 cagagaccct cagtgaagac tctgttgaag actttaagac catgctagaa 350

 agcctcccgg cagaggttca ggaagttctg ctatgaggat gcagctggcc 400

 ccagggatgt cctcaggcat ctctaggacc ttgctggacg gtggtggctg 450

 agacctgata tccacacaaa ggagcagact gtggaaatgc tggtgcagga 500

 gcaattccag gctgtcctgc ccgaaggagc tcagagctca agcacagaga 550

 tgtcatcctg gaatcagaat cactggctaa gtcttgctgc ttgcttcttg 600

 ctcagcctgc atatgagaag tcaaccaagc attctcttgg atgcaagatc 650

 caactgcacc catgggaaat ctgaacttcc actttctttg agcttgtctt 700

 tggttgtaat aagaatccat caaaacccat gtctggatct ctctttggct 750

 gaggcagctt tatttcctac agagtttctc tgtcctcttg ttaggacaat 800

 cagcctgctg ctttgggctt ttccaagagc ctatttttca tctgctggat 850

 gcctcttttt tttttttttt ttgcactttg tgacatgctt taatatatat 900

 attttttatg tatccaaaga ggtaatcaac tttaactttc agaattcatg 950

 aatcttggtt tggtggcatg aatgaaaggt tatgtaaccc caccagtaac 1000

 tcatttgggg tgcccttgaa atattaaagt ttggtcctca atcaaaaaaa 1050

 aaaaaaaaaa aaaaaaaaaa aaaa 1074

<210> 6015
<211> 154
<212> PRT
<213> Homo sapien

<400> 6015
 Met Leu Val Gln Glu Gln Phe Gln Ala Val Leu Pro Glu Gly Ala
   1               5                  10                  15

 Gln Ser Ser Ser Thr Glu Met Ser Ser Trp Asn Gln Asn His Trp
                  20                  25                  30

 Leu Ser Leu Ala Ala Cys Phe Leu Leu Ser Leu His Met Arg Ser
                  35                  40                  45

 Gln Pro Ser Ile Leu Leu Asp Ala Arg Ser Asn Cys Thr His Gly
                  50                  55                  60

 Lys Ser Glu Leu Pro Leu Ser Leu Ser Leu Ser Leu Val Val Ile
                  65                  70                  75

 Arg Ile His Gln Asn Pro Cys Leu Asp Leu Ser Leu Ala Glu Ala
                  80                  85                  90

 Ala Leu Phe Pro Thr Glu Phe Leu Cys Pro Leu Val Arg Thr Ile
                  95                 100                 105

 Ser Leu Leu Leu Trp Ala Phe Pro Arg Ala Tyr Phe Ser Ser Ala
                 110                 115                 120

 Gly Cys Leu Phe Phe Phe Phe Phe Leu His Phe Val Thr Cys Phe
                 125                 130                 135

 Asn Ile Tyr Ile Phe Tyr Val Ser Lys Glu Val Ile Asn Phe Asn
                 140                 145                 150

 Phe Gln Asn Ser


<210> 6016
<211> 3443
<212> DNA
<213> Homo sapien

<400> 6016
 ttgatgctct aaatgcagaa ttaatggaga cttcaatgac tgatatgtca 50

 attcttagtt tctttgaaca tttccatatt tctcctgtga agttgcattt 100

 gagtttgtct ttgggttccg gaggtgaaga atcagacaaa gaaaaacagg 150

 aaatgtttgc agttcattct gtcaacttgc tgttgaagag cataggtgct 200

 actctgactg atgtggatga ccttatattc aaacttgctt attatgaaat 250

 tcgatatcag ttctacaaga gagatcagct tatatggagt gttgttaggc 300

 attacagtga acagttcttg aaacagatgt atgtccttgt attggggtta 350

 gatgtacttg gaaacccatt tggattaatt agaggtctgt ctgaaggagt 400

 tgaagcttta ttctatgaac ccttccaggg tgctgttcaa ggccctgaag 450

 aatttgcaga ggggttagtg attggagtga gaagcctctt tggacacaca 500

 gtaggtggtg cagcaggagt tgtatctcga atcaccggtt ctgttgggaa 550

 aggtttggca gcaattacaa tggacaagga atatcagcaa aaaagaagag 600

 aagagttgag tcgacagccc agagattttg gagacagcct ggccagagga 650

 ggaaagggct ttctgcgagg agttgttggt ggagtgactg gaataataac 700

 aaaacctgtg gaaggtgcca aaaaggaagg agctgctgga ttctttaaag 750

 gaattggaaa agggcttgtg ggtgctgtgg cccgtccaac tggtggaatc 800

 gtagatatgg ccagtagtac cttccaaggc attcagaggg cagcagaatc 850

 aactgaggaa gtatctagcc tccgtccccc tcgcctgatc catgaagatg 900

 gcatcattcg tccttatgac agacaggaat ctgagggctc tgacttactt 950

 gagaatcata tcaaaaagtt ggaaggagag acttaccgat accactgtgc 1000

 tattcctgga agcaagaaga caatccttat ggttacaaat aggcgagtgt 1050

 tgtgtataaa ggaagttgaa atcctgggcc ttatgtgtgt agactggcaa 1100

 tgtccatttg aagattttgt atttcctcct agtgtcagtg aaaatgtgct 1150

 aaaaatttca gttaaggaac agggtctgtt ccacaaaaaa gacagtgcca 1200

 atcaaggctg tgttcgaaaa gtttacctga aggacaccgc cacagcagag 1250

 agagcatgta atgccattga ggatgcacag tcaacgagac agcagcaaaa 1300

 attgatgaag cagtcatcag tgagacttct cagaccccaa ttgccatctt 1350

 aatcacagac ctcaggggct ccaacaggga gaaaaaacaa tcactggtct 1400

 tgtctataag tcactctgct ttatcttgct aaagacaatt tttcaagcaa 1450

 tcctttagtt ttagttttct ggaatagcta gtattgggtt ttctagtttt 1500

 ttcacctttt agtttttact ctaattttgt aaccatgtat atgctagcag 1550

 tccacttcta cgccaccacc caaatgggtc agacccttga agaaacgtca 1600

 cttcaaactc agaatgaaat tttcattaat attaaaattg tgaagcaaag 1650

 gtcaataggc ttatatttaa ttaaagcctt actgaagaat aagaaatgag 1700

 cttagaatga ctagtgttct ttgaaaggtt tttttatttt tgtttttttg 1750

 gggttttttt tttttttttt gagaccgagt cttgctctgt cgcccaggct 1800

 ggaatgcagt ggtgcgatct tggctcactg caatctctgc ctctcgggtt 1850

 caagcggttc tactgcctca gcctcctgag tagctaggat tacaggtgtg 1900

 tgccaccacg cctgggtaat tttttttttt tttgtatttt tagtagagat 1950

 gagtttcacc atgttggtca gtctagtctc gaactcctga ccttgtgatc 2000

 cgcatgcctc agcctcccaa agtgctggga ttacaggcat gagccaccac 2050

 ggcccgccaa aaggctttaa cccatgaaca aatgttggat cctgacattt 2100

 tgtttaagag tgatttgttc aataattgaa ctgagttaac attcttggta 2150

 aaccaggtaa ttgaatgaag aaaggtcact aaagggagaa atgacatgtt 2200

 ttctattttc ttttcatgaa aacactgttt ttccccctaa taaagcatat 2250

 tttactttgg tgcttatttt tcctccttgc agtctaataa aaaaatctgg 2300

 acaatcaaac cttaaaatag ctacactctg ccctctgtaa tgtagcattc 2350

 ataaaaattt ggaagtattt acatcctctt tcaagatgag cttatatgac 2400

 acaattatta tttgctgata catgaaaata ctgcacttta agtttctcaa 2450

 gactctgaaa tatgtaaaat tcaatatttt tatattccca gaaattgttt 2500

 cttacaggtt gaaagtcttt taagggcatc acaaattaac atttactcct 2550

 aatgcacgcc tagaatgtat tttaaatact tactaagaag aatgaaaatt 2600

 ctttggttgt tttatatata aataaggcat atataatgac actgtgttct 2650

 gtgagggagc aggccctgtg agaatcaatt caggacagta tttttttttg 2700

 tcctttctcc atccttgatc agagataaac tattaaaact ttaaaaaata 2750

 ctcaaaaata tgtaagtttt ttggttgaac ctttagattt gctcataatg 2800

 tttaacataa caacatttat ttcaaatcac tgaattcatg gagatgtgga 2850

 cacgcttggt ttgctctatt tttgtttatg tgtgatagtg gttctgtcat 2900

 catcattcat gttttttaag gcctggtcat aaaactttaa attttactag 2950

 tgttacttaa tgtatattct aaaaagagaa tgcagtaact aatgccctaa 3000

 atgtttgatc tctgtttgtc attacttttt caaaattatt tttttctgta 3050

 aagtataata tataaaactt cttgcttaaa ttgaatttct atattagtgg 3100

 ttaattgcag tttattaaag ggatcattat cagtaatttc atagcaactg 3150

 ttctagtgtt ttgtgttttt aaaacagaat taggaatttg agatatctga 3200

 ttatattttt catatgaatc acagctgttg acaatgtccc atatatttaa 3250

 gaaattatat catactgata ctatttgtaa cattttgatt tgatttaatc 3300

 tccagggaca gaaataattc attggtaaag tgtaataatg cgttttttaa 3350

 aaatgctttg agaggtaatt acttgcatat gagagaaata aaacatttgg 3400

 cacattgttt acaggtgtga aaaaaaaaaa aaaaaaaaaa aaa 3443

<210> 6017
<211> 442
<212> PRT
<213> Homo sapien

<400> 6017
 Met Glu Thr Ser Met Thr Asp Met Ser Ile Leu Ser Phe Phe Glu
   1               5                  10                  15

 His Phe His Ile Ser Pro Val Lys Leu His Leu Ser Leu Ser Leu
                  20                  25                  30

 Gly Ser Gly Gly Glu Glu Ser Asp Lys Glu Lys Gln Glu Met Phe
                  35                  40                  45

 Ala Val His Ser Val Asn Leu Leu Leu Lys Ser Ile Gly Ala Thr
                  50                  55                  60

 Leu Thr Asp Val Asp Asp Leu Ile Phe Lys Leu Ala Tyr Tyr Glu
                  65                  70                  75

 Ile Arg Tyr Gln Phe Tyr Lys Arg Asp Gln Leu Ile Trp Ser Val
                  80                  85                  90

 Val Arg His Tyr Ser Glu Gln Phe Leu Lys Gln Met Tyr Val Leu
                  95                 100                 105

 Val Leu Gly Leu Asp Val Leu Gly Asn Pro Phe Gly Leu Ile Arg
                 110                 115                 120

 Gly Leu Ser Glu Gly Val Glu Ala Leu Phe Tyr Glu Pro Phe Gln
                 125                 130                 135

 Gly Ala Val Gln Gly Pro Glu Glu Phe Ala Glu Gly Leu Val Ile
                 140                 145                 150

 Gly Val Arg Ser Leu Phe Gly His Thr Val Gly Gly Ala Ala Gly
                 155                 160                 165

 Val Val Ser Arg Ile Thr Gly Ser Val Gly Lys Gly Leu Ala Ala
                 170                 175                 180

 Ile Thr Met Asp Lys Glu Tyr Gln Gln Lys Arg Arg Glu Glu Leu
                 185                 190                 195

 Ser Arg Gln Pro Arg Asp Phe Gly Asp Ser Leu Ala Arg Gly Gly
                 200                 205                 210

 Lys Gly Phe Leu Arg Gly Val Val Gly Gly Val Thr Gly Ile Ile
                 215                 220                 225

 Thr Lys Pro Val Glu Gly Ala Lys Lys Glu Gly Ala Ala Gly Phe
                 230                 235                 240

 Phe Lys Gly Ile Gly Lys Gly Leu Val Gly Ala Val Ala Arg Pro
                 245                 250                 255

 Thr Gly Gly Ile Val Asp Met Ala Ser Ser Thr Phe Gln Gly Ile
                 260                 265                 270

 Gln Arg Ala Ala Glu Ser Thr Glu Glu Val Ser Ser Leu Arg Pro
                 275                 280                 285

 Pro Arg Leu Ile His Glu Asp Gly Ile Ile Arg Pro Tyr Asp Arg
                 290                 295                 300

 Gln Glu Ser Glu Gly Ser Asp Leu Leu Glu Asn His Ile Lys Lys
                 305                 310                 315

 Leu Glu Gly Glu Thr Tyr Arg Tyr His Cys Ala Ile Pro Gly Ser
                 320                 325                 330

 Lys Lys Thr Ile Leu Met Val Thr Asn Arg Arg Val Leu Cys Ile
                 335                 340                 345

 Lys Glu Val Glu Ile Leu Gly Leu Met Cys Val Asp Trp Gln Cys
                 350                 355                 360

 Pro Phe Glu Asp Phe Val Phe Pro Pro Ser Val Ser Glu Asn Val
                 365                 370                 375

 Leu Lys Ile Ser Val Lys Glu Gln Gly Leu Phe His Lys Lys Asp
                 380                 385                 390

 Ser Ala Asn Gln Gly Cys Val Arg Lys Val Tyr Leu Lys Asp Thr
                 395                 400                 405

 Ala Thr Ala Glu Arg Ala Cys Asn Ala Ile Glu Asp Ala Gln Ser
                 410                 415                 420

 Thr Arg Gln Gln Gln Lys Leu Met Lys Gln Ser Ser Val Arg Leu
                 425                 430                 435

 Leu Arg Pro Gln Leu Pro Ser
                 440

<210> 6018
<211> 2473
<212> DNA
<213> Homo sapien

<400> 6018
 aatcgcgaaa cccggcgagc ggcgcgctgg ctatcgagcg agcggggcgg 50

 aaccgggagt tgcgccgccg ctcgggcgcc gggctccgtc gcggccgcag 100

 ccccgcgggt cgccctcccg tgcctcgccc gcggacaccc tggccgtgga 150

 caccctggcc gtgggcaccc gcggggcgcg gcgcgggcgc tgcgcggcgg 200

 cggcggcggc atgaaggtca cgtcgctcga cgggcgccag ctgcgcaaga 250

 tgctccgcaa ggaggcggcg gcgcgctgcg tggtgctcga ctgccggccc 300

 tatctggcct tcgctgcctc gaacgtgcgc ggctcgctca acgtcaacct 350

 caactcggtg gtgctgcggc gggcccgggg cggcgcggtg tcggcgcgct 400

 acgtgctgcc cgacgaggcg gcgcgcgcgc ggctcctgca ggagggcggc 450

 ggcggcgtcg cggccgtggt ggtgctggac cagggcagcc gccactggca 500

 gaagctgcga gaggagagcg ccgcgcgtgt cgtcctcacc tcgctactcg 550

 cttgcctacc cgccggcccg cgggtctact tcctcaaagg gggatatgag 600

 actttctact cggaatatcc tgagtgttgc gtggatgtaa aacccatttc 650

 acaagagaag attgagagtg agagagccct catcagccag tgtggaaaac 700

 cagtggtaaa tgtcagctac aggccagctt atgaccaggg tggcccagtt 750

 gaaatccttc ccttcctcta ccttggaagt gcctaccatg catccaagtg 800

 cgagttcctc gccaacttgc acatcacagc cctgctgaat gtctcccgac 850

 ggacctccga ggcctgcatg acccacctac actacaaatg gatccctgtg 900

 gaagacagcc acacggctga cattagctcc cactttcaag aagcaataga 950

 cttcattgac tgtgtcaggg aaaagggagg caaggtcctg gtccactgtg 1000

 aggctgggat ctcccgttca cccaccatct gcatggctta ccttatgaag 1050

 accaagcagt tccgcctgaa ggaggccttc gattacatca agcagaggag 1100

 gagcatggtc tcgcccaact ttggcttcat gggccagctc ctgcagtacg 1150

 aatctgagat cctgccctcc acgcccaacc cccagcctcc ctcctgccaa 1200

 ggggaggcag caggctcttc actgataggc catttgcaga cactgagccc 1250

 tgacatgcag ggtgcctact gcacattccc tgcctcggtg ctggcaccgg 1300

 tgcctaccca ctcaacagtc tcagagctca gcagaagccc tgtggcaacg 1350

 gccacatcct gctaaaactg ggatggagga atcggcccag ccccaagagc 1400

 aactgtgatt tttgttttta agactcatgg acatttcata cctgtgcaat 1450

 actgaagacc tcattctgtc atgctgcccc agtgagatag tgagtggtca 1500

 ccaggcttgc aaatgaactt cagacggacc tcagggtagg ttctcgggac 1550

 tgaaggaagg ccaagccatt acgggagcac agcatgtgct gactactgta 1600

 cttccagacc cctgccctct tgggactgcc cagtccttgc acctcagagt 1650

 tcgccttttc atttcaagca taagccaata aatacctgca gcaacgtggg 1700

 agaaagaagt tgctggacca ggagaaaagg cagttatgaa gccaattcat 1750

 tttgaaggaa gcacaatttc caccttattt tttgaacttt ggcagtttca 1800

 atgtctgtct ctgttgcttc ggggcataag ctgatcaccg tctagttggg 1850

 aaagtcaccc tacagggttt gtagggacat gatcagcatc ctgatttgaa 1900

 ccctgaaatg ttgtgtagac accctcttgg gtccaatgag gtagttggtt 1950

 gaagtagcaa gatgttggct tttctggatt ttttttgcca tgggttcttc 2000

 actgaccttg gactttggca tgattcttag tcatacttga acttgtctca 2050

 ttccacctct tctcagagca actcttcctt tgggaaaaga gttcttcaga 2100

 tcatagacca aaaaagtcat accttcgagg tggtagcagt agattccagg 2150

 aggagaaggg tacttgctag gtatcctggg tcagtggcgg tgcaaactgg 2200

 tttcctcagc tgcctgtcct tctgtgtgct tatgtctctt gtgacaattg 2250

 ttttcctccc tgcccctgga ggttgtcttc aactgtggac ttctgggatt 2300

 tgcagatttt gcaacgtggt actacttttt tttctttttg tctgttagtt 2350

 atttctccag gggaaaaggc aataattttc taagacccgt gtgaatgtga 2400

 agaaaagcag tatgttactg gttgttgttg ttgttcttgt tttttatatg 2450

 taaaataaaa atagtgaaag gag 2473

<210> 6019
<211> 384
<212> PRT
<213> Homo sapien

<400> 6019
 Met Lys Val Thr Ser Leu Asp Gly Arg Gln Leu Arg Lys Met Leu
   1               5                  10                  15

 Arg Lys Glu Ala Ala Ala Arg Cys Val Val Leu Asp Cys Arg Pro
                  20                  25                  30

 Tyr Leu Ala Phe Ala Ala Ser Asn Val Arg Gly Ser Leu Asn Val
                  35                  40                  45

 Asn Leu Asn Ser Val Val Leu Arg Arg Ala Arg Gly Gly Ala Val
                  50                  55                  60

 Ser Ala Arg Tyr Val Leu Pro Asp Glu Ala Ala Arg Ala Arg Leu
                  65                  70                  75

 Leu Gln Glu Gly Gly Gly Gly Val Ala Ala Val Val Val Leu Asp
                  80                  85                  90

 Gln Gly Ser Arg His Trp Gln Lys Leu Arg Glu Glu Ser Ala Ala
                  95                 100                 105

 Arg Val Val Leu Thr Ser Leu Leu Ala Cys Leu Pro Ala Gly Pro
                 110                 115                 120

 Arg Val Tyr Phe Leu Lys Gly Gly Tyr Glu Thr Phe Tyr Ser Glu
                 125                 130                 135

 Tyr Pro Glu Cys Cys Val Asp Val Lys Pro Ile Ser Gln Glu Lys
                 140                 145                 150

 Ile Glu Ser Glu Arg Ala Leu Ile Ser Gln Cys Gly Lys Pro Val
                 155                 160                 165

 Val Asn Val Ser Tyr Arg Pro Ala Tyr Asp Gln Gly Gly Pro Val
                 170                 175                 180

 Glu Ile Leu Pro Phe Leu Tyr Leu Gly Ser Ala Tyr His Ala Ser
                 185                 190                 195

 Lys Cys Glu Phe Leu Ala Asn Leu His Ile Thr Ala Leu Leu Asn
                 200                 205                 210

 Val Ser Arg Arg Thr Ser Glu Ala Cys Met Thr His Leu His Tyr
                 215                 220                 225

 Lys Trp Ile Pro Val Glu Asp Ser His Thr Ala Asp Ile Ser Ser
                 230                 235                 240

 His Phe Gln Glu Ala Ile Asp Phe Ile Asp Cys Val Arg Glu Lys
                 245                 250                 255

 Gly Gly Lys Val Leu Val His Cys Glu Ala Gly Ile Ser Arg Ser
                 260                 265                 270

 Pro Thr Ile Cys Met Ala Tyr Leu Met Lys Thr Lys Gln Phe Arg
                 275                 280                 285

 Leu Lys Glu Ala Phe Asp Tyr Ile Lys Gln Arg Arg Ser Met Val
                 290                 295                 300

 Ser Pro Asn Phe Gly Phe Met Gly Gln Leu Leu Gln Tyr Glu Ser
                 305                 310                 315

 Glu Ile Leu Pro Ser Thr Pro Asn Pro Gln Pro Pro Ser Cys Gln
                 320                 325                 330

 Gly Glu Ala Ala Gly Ser Ser Leu Ile Gly His Leu Gln Thr Leu
                 335                 340                 345

 Ser Pro Asp Met Gln Gly Ala Tyr Cys Thr Phe Pro Ala Ser Val
                 350                 355                 360

 Leu Ala Pro Val Pro Thr His Ser Thr Val Ser Glu Leu Ser Arg
                 365                 370                 375

 Ser Pro Val Ala Thr Ala Thr Ser Cys
                 380

<210> 6020
<211> 1723
<212> DNA
<213> Homo sapien

<400> 6020
 gggggagtgc gaatttcttg gcctgtcggc aggtgctttc tcaaaggccc 50

 cacagtcctc cacttcctgg ggaggtagct gcagaataaa accagcagag 100

 actccttttc tcctaaccgt cccggccacc gctgcctcag cctctgcctc 150

 ccagcctctt tctgagggaa aggacaagat gaagtggaag gcgcttttca 200

 ccgcggccat cctgcaggca cagttgccga ttacagaggc acagagcttt 250

 ggcctgctgg atcccaaact ctgctacctg ctggatggaa tcctcttcat 300

 ctatggtgtc attctcactg ccttgttcct gagagtgaag ttcagcagga 350

 gcgcagacgc ccccgcgtac cagcagggcc agaaccagct ctataacgag 400

 ctcaatctag gacgaagaga ggagtacgat gttttggaca agagacgtgg 450

 ccgggaccct gagatggggg gaaagccgag aaggaagaac cctcaggaag 500

 gcctgtacaa tgaactgcag aaagataaga tggcggaggc ctacagtgag 550

 attgggatga aaggcgagcg ccggaggggc aaggggcacg atggccttta 600

 ccagggtctc agtacagcca ccaaggacac ctacgacgcc cttcacatgc 650

 aggccctgcc ccctcgctaa cagccagggg atttcaccac tcaaaggcca 700

 gacctgcaga cgcccagatt atgagacaca ggatgaagca tttacaaccc 750

 ggttcactct tctcagccac tgaagtattc ccctttatgt acaggatgct 800

 ttggttatat ttagctccaa accttcacac acagactgtt gtccctgcac 850

 tctttaaggg agtgtactcc cagggcttac ggccctgcct tgggccctct 900

 ggtttgccgg tggtgcaggt agacctgtct cctggcggtt cctcgttctc 950

 cctgggaggc gggcgcactg cctctcacag ctgagttgtt gagtctgttt 1000

 tgtaaagtcc ccagagaaag cgcagatgct agcacatgcc ctaatgtctg 1050

 tatcactctg tgtctgagtg gcttcactcc tgctgtaaat ttggcttctg 1100

 ttgtcacctt cacctccttt caaggtaact gtactgggcc atgttgtgcc 1150

 tccctggtga gagggccggg cagaggggca gatggaaagg agcctaggcc 1200

 aggtgcaacc agggagctgc aggggcatgg gaaggtgggc gggcagggga 1250

 gggtcagcca gggcctgcga gggcagcggg agcctccctg cctcaggcct 1300

 ctgtgccgca ccattgaact gtaccatgtg ctacaggggc cagaagatga 1350

 acagactgac cttgatgagc tgtgcacaaa gtggcataaa aaacagtgtg 1400

 gttacacagt gtgaataaag tgctgcggag caagaggagg ccgttgattc 1450

 acttcacgct ttcagcgaat gacaaaatca tctttgtgaa ggcctcgcag 1500

 gaagacgcaa cacatgggac ctataactgc ccagcggaca gtggcaggac 1550

 aggaaaaacc cgtcaatgta ctagggtact gctgcgtcat tacagggcac 1600

 aggccatgga tggaaaacgc tctctgctct gctttttttc tactgtttta 1650

 atttatactg gcatgctatt gccttcctat tttgcataat aaatgcttca 1700

 gtgaaaatgc agctttactc taa 1723

<210> 6021
<211> 163
<212> PRT
<213> Homo sapien

<400> 6021
 Met Lys Trp Lys Ala Leu Phe Thr Ala Ala Ile Leu Gln Ala Gln
   1               5                  10                  15

 Leu Pro Ile Thr Glu Ala Gln Ser Phe Gly Leu Leu Asp Pro Lys
                  20                  25                  30

 Leu Cys Tyr Leu Leu Asp Gly Ile Leu Phe Ile Tyr Gly Val Ile
                  35                  40                  45

 Leu Thr Ala Leu Phe Leu Arg Val Lys Phe Ser Arg Ser Ala Asp
                  50                  55                  60

 Ala Pro Ala Tyr Gln Gln Gly Gln Asn Gln Leu Tyr Asn Glu Leu
                  65                  70                  75

 Asn Leu Gly Arg Arg Glu Glu Tyr Asp Val Leu Asp Lys Arg Arg
                  80                  85                  90

 Gly Arg Asp Pro Glu Met Gly Gly Lys Pro Arg Arg Lys Asn Pro
                  95                 100                 105

 Gln Glu Gly Leu Tyr Asn Glu Leu Gln Lys Asp Lys Met Ala Glu
                 110                 115                 120

 Ala Tyr Ser Glu Ile Gly Met Lys Gly Glu Arg Arg Arg Gly Lys
                 125                 130                 135

 Gly His Asp Gly Leu Tyr Gln Gly Leu Ser Thr Ala Thr Lys Asp
                 140                 145                 150

 Thr Tyr Asp Ala Leu His Met Gln Ala Leu Pro Pro Arg
                 155                 160

<210> 6022
<211> 2422
<212> DNA
<213> Homo sapien

<400> 6022
 ggcacgaggg gcggcagcgg ttggaggctt cgcccggctt tgcagcgggg 50

 acttcggcgg cggcgcctca ggcacctcgg cccggacacg atgaggcgag 100

 tggtacgaca gagcaagttt cggcatgtat ttgggcaagc ggtgaaaaat 150

 gaccagtgct atgatgacat ccgggtttct cgtgtgacct gggatagttc 200

 cttttgtgct gtcaatccca gatttgttgc cataatcata gaggcaagtg 250

 ggggaggagc gttccttgtc ctccctctgc acaagactgg tcgaattgac 300

 aaatcttacc ctacagtatg tggccacaca ggaccagtgc tggacataga 350

 ctggtgccca cataacgatc aggtcattgc cagcggttca gaggactgca 400

 cggtcatggt atggcagatc ccagaaaatg gactcaccct ttccctgact 450

 gaacctgtgg tgattttgga aggccactca aagagagtcg gcatcgtggc 500

 ttggcatcca acggcccgca atgtgcttct tagtgcaggc tgtgataatg 550

 ccattatcat ctggaatgtg ggaacagggg aagcccttat aaacttggac 600

 gatatgcatt cagacatgat ttacaatgtg agctggaacc ggaatggcag 650

 tctgatctgc acagcttcca aagacaagaa agtgagagtc attgatccca 700

 ggaaacaaga gattgttgct gagaaggaga aagcacatga aggagcaaga 750

 cccatgagag ccatcttcct ggccgatggc aatgtcttca ccactgggtt 800

 cagccgcatg agcgagcggc agctggctct ctggaatccg aaaaatatgc 850

 aggaaccaat tgctcttcat gagatggaca ctagcaatgg ggtgttgctg 900

 cctttctatg accctgacac cagcatcatt tacttatgtg gaaagggtga 950

 cagcagtatt cgctattttg agatcacgga tgaatccccg tacgtccact 1000

 acctcaacac attcagcagc aaggagcctc agagagggat gggttacatg 1050

 cccaagaggg gacttgatgt taacaaatgt gagattgcca gattcttcaa 1100

 acttcatgag agaaagtgtg aacctattat tatgactgtt cccaggaagt 1150

 ctgacctttt ccaagatgac ctgtatcctg acacagcggg gccagaggcc 1200

 gcgctggagg cagaagagtg gttcgaaggc aagaatgcag acccaatcct 1250

 catctccttg aagcacgggt acattccagg caaaaacagg gatctcaagg 1300

 tggtcaagaa gaacattctg gatagcaagc ccactgcaaa caagaagtgc 1350

 gacctgatca gcatccccaa gaaaaccaca gacacggcca gtgtgcaaaa 1400

 tgaagccaag ttggatgaga ttttaaaaga gatcaaatct ataaaagaca 1450

 caatctgcaa tcaagatgag cgtatttcca agttagaaca gcagatggca 1500

 aagatagcag cctgaaggtc ccacccccac ccctacagaa aaaatgggag 1550

 caagaacttg tgcttgggag ctggttattg gtgtggtcct agggagggcg 1600

 gaaagggagg cactgccatt tggagacatt ccatttcaga tttgtcaacc 1650

 agcgataggc cacattccag taagaactca atttgtctcc caaatttgca 1700

 gaaacaaaac gtgatttaaa agctgagctt tttatcagaa agcttttttg 1750

 atgttttaag tgttatgtga cttgttgaac tttttaaaaa gtgctacttt 1800

 taaaatccca gatactctga attttagaaa acaaactaat tctgattgtg 1850

 tcgtgcccaa gtaccctttt ttttttaatg aatagggacc aatgccacat 1900

 tgctttttat atttctttct tttttaatgt tgccaaaacc aaaagtagct 1950

 ttgttttcct ttgtattttg ctactttgca gtatttgtgt gtgtggtttt 2000

 ttttccttaa tttgaaaggg acagcactgt gtatgtttat aaactaaatg 2050

 aagataagat attattttgt ataaacattc atctgagaac aatcaaagca 2100

 gtagccacat ggtgctggct cctttgcagc acaaacctgg tcattttgat 2150

 gactgtacaa caggaagact tgaaaaatca cgtggattca tattaccacc 2200

 gctctcattt catggagtct tctgatcaaa aaagctcacg tcgtatttct 2250

 tcttttcctt tctcttttct agaaattggg tgtttgtacc agaatggaat 2300

 tttgcttctc ggttatcctg tgcttcagat gattataatc taacccaaaa 2350

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2400

 aaaaaaaaaa aaaaaaaaaa aa 2422

<210> 6023
<211> 474
<212> PRT
<213> Homo sapien

<400> 6023
 Met Arg Arg Val Val Arg Gln Ser Lys Phe Arg His Val Phe Gly
   1               5                  10                  15

 Gln Ala Val Lys Asn Asp Gln Cys Tyr Asp Asp Ile Arg Val Ser
                  20                  25                  30

 Arg Val Thr Trp Asp Ser Ser Phe Cys Ala Val Asn Pro Arg Phe
                  35                  40                  45

 Val Ala Ile Ile Ile Glu Ala Ser Gly Gly Gly Ala Phe Leu Val
                  50                  55                  60

 Leu Pro Leu His Lys Thr Gly Arg Ile Asp Lys Ser Tyr Pro Thr
                  65                  70                  75

 Val Cys Gly His Thr Gly Pro Val Leu Asp Ile Asp Trp Cys Pro
                  80                  85                  90

 His Asn Asp Gln Val Ile Ala Ser Gly Ser Glu Asp Cys Thr Val
                  95                 100                 105

 Met Val Trp Gln Ile Pro Glu Asn Gly Leu Thr Leu Ser Leu Thr
                 110                 115                 120

 Glu Pro Val Val Ile Leu Glu Gly His Ser Lys Arg Val Gly Ile
                 125                 130                 135

 Val Ala Trp His Pro Thr Ala Arg Asn Val Leu Leu Ser Ala Gly
                 140                 145                 150

 Cys Asp Asn Ala Ile Ile Ile Trp Asn Val Gly Thr Gly Glu Ala
                 155                 160                 165

 Leu Ile Asn Leu Asp Asp Met His Ser Asp Met Ile Tyr Asn Val
                 170                 175                 180

 Ser Trp Asn Arg Asn Gly Ser Leu Ile Cys Thr Ala Ser Lys Asp
                 185                 190                 195

 Lys Lys Val Arg Val Ile Asp Pro Arg Lys Gln Glu Ile Val Ala
                 200                 205                 210

 Glu Lys Glu Lys Ala His Glu Gly Ala Arg Pro Met Arg Ala Ile
                 215                 220                 225

 Phe Leu Ala Asp Gly Asn Val Phe Thr Thr Gly Phe Ser Arg Met
                 230                 235                 240

 Ser Glu Arg Gln Leu Ala Leu Trp Asn Pro Lys Asn Met Gln Glu
                 245                 250                 255

 Pro Ile Ala Leu His Glu Met Asp Thr Ser Asn Gly Val Leu Leu
                 260                 265                 270

 Pro Phe Tyr Asp Pro Asp Thr Ser Ile Ile Tyr Leu Cys Gly Lys
                 275                 280                 285

 Gly Asp Ser Ser Ile Arg Tyr Phe Glu Ile Thr Asp Glu Ser Pro
                 290                 295                 300

 Tyr Val His Tyr Leu Asn Thr Phe Ser Ser Lys Glu Pro Gln Arg
                 305                 310                 315

 Gly Met Gly Tyr Met Pro Lys Arg Gly Leu Asp Val Asn Lys Cys
                 320                 325                 330

 Glu Ile Ala Arg Phe Phe Lys Leu His Glu Arg Lys Cys Glu Pro
                 335                 340                 345

 Ile Ile Met Thr Val Pro Arg Lys Ser Asp Leu Phe Gln Asp Asp
                 350                 355                 360

 Leu Tyr Pro Asp Thr Ala Gly Pro Glu Ala Ala Leu Glu Ala Glu
                 365                 370                 375

 Glu Trp Phe Glu Gly Lys Asn Ala Asp Pro Ile Leu Ile Ser Leu
                 380                 385                 390

 Lys His Gly Tyr Ile Pro Gly Lys Asn Arg Asp Leu Lys Val Val
                 395                 400                 405

 Lys Lys Asn Ile Leu Asp Ser Lys Pro Thr Ala Asn Lys Lys Cys
                 410                 415                 420

 Asp Leu Ile Ser Ile Pro Lys Lys Thr Thr Asp Thr Ala Ser Val
                 425                 430                 435

 Gln Asn Glu Ala Lys Leu Asp Glu Ile Leu Lys Glu Ile Lys Ser
                 440                 445                 450

 Ile Lys Asp Thr Ile Cys Asn Gln Asp Glu Arg Ile Ser Lys Leu
                 455                 460                 465

 Glu Gln Gln Met Ala Lys Ile Ala Ala
                 470

<210> 6024
<211> 1014
<212> DNA
<213> Homo sapien

<400> 6024
 ttcctcagaa acgagcaaac ctgaaagcta ctctctcagc ttcagaggga 50

 aaaaatggtt gtagatttct ggacttggga gcagacattt caagaactaa 100

 tccaagaggc aaaaccccgg gccacatgga cgctgaagtt ggatggcaac 150

 cttcagctag actgcctggc tcaagggtgg aagcaatacc aacagagagc 200

 atttggctgg ttccggtgtt cctcctgcca gcgaagttgg gcttccgcca 250

 agttgcagat tctgtgccac acgtactggg agcactggac atcccagggt 300

 caggtgcgta tgaggctctt tggccaaagg tgccagaagt gctcctggtc 350

 ccaatatgag atgcctgagt tctcctcgga tagcaccatg aggattctga 400

 gcaacctggt gcagcatata ctgaagaaat actatggaaa tggcatgagg 450

 aagtctccag aaatgccagt aatcctggaa gtgtccctgg aaggatccca 500

 tgacacagcc aattgtgagg catgcacttt gggcatatgt ggacagggct 550

 taaaaagcta catgacaaag ccgtccaaat ccctactccc ccacctaaag 600

 actgggaatt cctcacctgg aattggtgct gtgtacctcg caaaccaagc 650

 caagaaccag tcagatgagg caaaagaggc taaggggagt gggtatgaga 700

 aattagggcc cagtcgagac ccagatccac tgaacatctg tgtctttatt 750

 ttgctgcttg tatttattgt agtcaaatgc tttacatcag aatgatgaaa 800

 ataggcttgc cactttctct tattttaatt ccatggtagt caatgaactg 850

 gctgccactt taatataact gaaaattcat tttgagacca agcaggatca 900

 agtttgtaga ataaacactg gtttcctagc tatcctctga aaacagtatg 950

 aaacatgacc aagtacataa tggatttagt aataaatatt gtcgaattgc 1000

 taaaaaaaaa aaaa 1014

<210> 6025
<211> 246
<212> PRT
<213> Homo sapien

<400> 6025
 Met Val Val Asp Phe Trp Thr Trp Glu Gln Thr Phe Gln Glu Leu
   1               5                  10                  15

 Ile Gln Glu Ala Lys Pro Arg Ala Thr Trp Thr Leu Lys Leu Asp
                  20                  25                  30

 Gly Asn Leu Gln Leu Asp Cys Leu Ala Gln Gly Trp Lys Gln Tyr
                  35                  40                  45

 Gln Gln Arg Ala Phe Gly Trp Phe Arg Cys Ser Ser Cys Gln Arg
                  50                  55                  60

 Ser Trp Ala Ser Ala Lys Leu Gln Ile Leu Cys His Thr Tyr Trp
                  65                  70                  75

 Glu His Trp Thr Ser Gln Gly Gln Val Arg Met Arg Leu Phe Gly
                  80                  85                  90

 Gln Arg Cys Gln Lys Cys Ser Trp Ser Gln Tyr Glu Met Pro Glu
                  95                 100                 105

 Phe Ser Ser Asp Ser Thr Met Arg Ile Leu Ser Asn Leu Val Gln
                 110                 115                 120

 His Ile Leu Lys Lys Tyr Tyr Gly Asn Gly Met Arg Lys Ser Pro
                 125                 130                 135

 Glu Met Pro Val Ile Leu Glu Val Ser Leu Glu Gly Ser His Asp
                 140                 145                 150

 Thr Ala Asn Cys Glu Ala Cys Thr Leu Gly Ile Cys Gly Gln Gly
                 155                 160                 165

 Leu Lys Ser Tyr Met Thr Lys Pro Ser Lys Ser Leu Leu Pro His
                 170                 175                 180

 Leu Lys Thr Gly Asn Ser Ser Pro Gly Ile Gly Ala Val Tyr Leu
                 185                 190                 195

 Ala Asn Gln Ala Lys Asn Gln Ser Asp Glu Ala Lys Glu Ala Lys
                 200                 205                 210

 Gly Ser Gly Tyr Glu Lys Leu Gly Pro Ser Arg Asp Pro Asp Pro
                 215                 220                 225

 Leu Asn Ile Cys Val Phe Ile Leu Leu Leu Val Phe Ile Val Val
                 230                 235                 240

 Lys Cys Phe Thr Ser Glu
                 245

<210> 6026
<211> 1425
<212> DNA
<213> Homo sapien

<400> 6026
 cagtctgaga acaagaaaga agaacttctg tctcgagggt ctcactgtca 50

 accaggccag agtgcagtga agatcatacc tcactacatc cgtgaactcc 100

 cgggctcctc ccacctaagt ctcttgagta gctgggactt caggagactg 150

 aagccaagga taccagcaga gccaacattt gcttcaagtt cctgggcctg 200

 ctgacagcgt gcaggatgct gttggaaccc ggcagaggct gctgtgccct 250

 ggccatcctg ctggcaattg tggacatcca gtctggtgga tgcattaaca 300

 tcaccagctc agcttcccag gaaggaacgc gactaaactt aatctgtact 350

 gtatggcata agaaagaaga ggctgagggg tttgtagtgt ttttgtgcaa 400

 ggacaggtct ggagactgtt ctcctgagac cagtttaaaa cagctgagac 450

 ttaaaaggga tcctgggata gatggtgttg gtgaaatatc atctcagttg 500

 atgttcacca taagccaagt cacaccgttg cacagtggga cctaccagtg 550

 ttgtgccaga agccagaagt caggtatccg ccttcagggc cattttttct 600

 ccattctatt cacagagaca gggaactaca cagtgacggg attgaaacaa 650

 agacaacacc ttgagttcag ccataatgaa ggcactctca gttcaggctt 700

 cctacaagaa aaggtctggg taatgctggt caccagcctt gtggcccttc 750

 aagctttgta agcctgtcca aaagaacttt taaaacagct acagcaagat 800

 gagtctgact atggcttagt atctttctca ttacaatagg cacagagaag 850

 aatgcaacag ggcacagggg aagagatgct aaatatacca agaatctgtg 900

 gaaatataag ctggggcaaa tcagtgtaat ccttgacttt gctcctcacc 950

 atcagggcaa acttgccttc ttccctccta agctccagta aataaacaga 1000

 acagctttca ccaaagtggg tagtatagtc ctcaaatatc ggataaatat 1050

 atgcgttttt gtaccccaga aaaacttttc ctccctcttc atcaacatag 1100

 taaaataagt caaacaaaat gagaacacca aattttgggg gaataaattt 1150

 ttatttaaca ctgcaaagga aagagagaga aaacaagcaa agataggtag 1200

 gacagaaagg aagacagcca gatccagtga ttgacttggc atgaaaatga 1250

 gaaaatgcag acagacctca acattcaaca ttcaacaaca tccatacagc 1300

 actgctggag gaagaggaag atttgtgcag accaagagca ccacagacta 1350

 caactgccca gcttcatcta aatacttgtt aacctctttg gtcatttctc 1400

 tttttaaata aatgcccata gcagt 1425

<210> 6027
<211> 181
<212> PRT
<213> Homo sapien

<400> 6027
 Met Leu Leu Glu Pro Gly Arg Gly Cys Cys Ala Leu Ala Ile Leu
   1               5                  10                  15

 Leu Ala Ile Val Asp Ile Gln Ser Gly Gly Cys Ile Asn Ile Thr
                  20                  25                  30

 Ser Ser Ala Ser Gln Glu Gly Thr Arg Leu Asn Leu Ile Cys Thr
                  35                  40                  45

 Val Trp His Lys Lys Glu Glu Ala Glu Gly Phe Val Val Phe Leu
                  50                  55                  60

 Cys Lys Asp Arg Ser Gly Asp Cys Ser Pro Glu Thr Ser Leu Lys
                  65                  70                  75

 Gln Leu Arg Leu Lys Arg Asp Pro Gly Ile Asp Gly Val Gly Glu
                  80                  85                  90

 Ile Ser Ser Gln Leu Met Phe Thr Ile Ser Gln Val Thr Pro Leu
                  95                 100                 105

 His Ser Gly Thr Tyr Gln Cys Cys Ala Arg Ser Gln Lys Ser Gly
                 110                 115                 120

 Ile Arg Leu Gln Gly His Phe Phe Ser Ile Leu Phe Thr Glu Thr
                 125                 130                 135

 Gly Asn Tyr Thr Val Thr Gly Leu Lys Gln Arg Gln His Leu Glu
                 140                 145                 150

 Phe Ser His Asn Glu Gly Thr Leu Ser Ser Gly Phe Leu Gln Glu
                 155                 160                 165

 Lys Val Trp Val Met Leu Val Thr Ser Leu Val Ala Leu Gln Ala
                 170                 175                 180

 Leu


<210> 6028
<211> 1714
<212> DNA
<213> Homo sapien

<400> 6028
 ggggcatttt gtgcctgcct agctatccag acagagcagc taccctcagc 50

 tctagctgat actacagaca gtacaacaga tcaagaagta tggcagtgac 100

 aactcgtttg acacggttgc acgaaaagat cctgcaaaat cattttggag 150

 ggaagcggct tagccttctc tataagggta gtgtccatgg attccgtaat 200

 ggagttttgc ttgacagatg ttgtaatcaa gggcctactc taacagtgat 250

 ttatagtgaa gatcatatta ttggagcata tgcggaagag agttaccagg 300

 aaggaaagta tgcttccatc atcctttttg cacttcaaga tactaaaatt 350

 tcagaatgga aactaggact atgtacacca gaaacactgt tttgttgtga 400

 tgttacaaaa tataactccc caactaattt ccagatagat ggaagaaata 450

 gaaaagtgat tatggactta aagacaatgg aaaatcttgg acttgctcaa 500

 aattgtacta tctctattca ggattatgaa gtttttcgat gcgaagattc 550

 actggatgaa agaaagataa aaggggtcat tgagctcagg aagagcttac 600

 tgtctgcctt gagaacttat gaaccatatg gatccctggt tcaacaaata 650

 cgaattctgc tgctgggtcc aattggagct gggaagtcca gctttttcaa 700

 ctcagtgagg tctgttttcc aagggcatgt aacgcatcag gctttggtgg 750

 gcactaatac aactgggata tctgagaagt ataggacata ctctattaga 800

 gacgggaaag atggcaaata cctgccgttt attctgtgtg actcactggg 850

 gctgagtgag aaagaaggcg gcctgtgcag ggatgacata ttctatatct 900

 tgaacggtaa cattcgtgat agataccagt ttaatcccat ggaatcaatc 950

 aaattaaatc atcatgacta cattgattcc ccatcgctga aggacagaat 1000

 tcattgtgtg gcatttgtat ttgatgccag ctctattcaa tacttctcct 1050

 ctcagatgat agtaaagatc aaaagaattc gaagggagtt ggtaaacgct 1100

 ggtgtggtac atgtggcttt gctcactcat gtggatagca tggatttgat 1150

 tacaaaaggt gaccttatag aaatagagag atgtgagcct gtgaggtcca 1200

 agctagagga agtccaaaga aaacttggat ttgctctttc tgacatctcg 1250

 gtggttagca attattcctc tgagtgggag ctggaccctg taaaggatgt 1300

 tctaattctt tctgctctga gacgaatgct atgggctgca gatgacttct 1350

 tagaggattt gccttttgag caaataggga atctaaggga ggaaattatc 1400

 aactgtgcac aaggaaaaaa atagatatgt gaaaggttca cgtaaatttc 1450

 ctcacatcac agaagattaa aattcagaaa ggagaaaaca cagaccaaag 1500

 agaagtatct aagaccaaag ggatgtgttt tattaatgtc taggatgaag 1550

 aaatgcatag aacattgtag tacttgtaaa taactagaaa taacatgatt 1600

 tagtcataat tgtgaaaaat agtaataatt tttcttggat ttatgttctg 1650

 tatctgtgaa aaaataaatt tcttataaaa ctcggaaaaa aaaaaaaaaa 1700

 aaaaaaaaaa aaaa 1714

<210> 6029
<211> 444
<212> PRT
<213> Homo sapien

<400> 6029
 Met Ala Val Thr Thr Arg Leu Thr Arg Leu His Glu Lys Ile Leu
   1               5                  10                  15

 Gln Asn His Phe Gly Gly Lys Arg Leu Ser Leu Leu Tyr Lys Gly
                  20                  25                  30

 Ser Val His Gly Phe Arg Asn Gly Val Leu Leu Asp Arg Cys Cys
                  35                  40                  45

 Asn Gln Gly Pro Thr Leu Thr Val Ile Tyr Ser Glu Asp His Ile
                  50                  55                  60

 Ile Gly Ala Tyr Ala Glu Glu Ser Tyr Gln Glu Gly Lys Tyr Ala
                  65                  70                  75

 Ser Ile Ile Leu Phe Ala Leu Gln Asp Thr Lys Ile Ser Glu Trp
                  80                  85                  90

 Lys Leu Gly Leu Cys Thr Pro Glu Thr Leu Phe Cys Cys Asp Val
                  95                 100                 105

 Thr Lys Tyr Asn Ser Pro Thr Asn Phe Gln Ile Asp Gly Arg Asn
                 110                 115                 120

 Arg Lys Val Ile Met Asp Leu Lys Thr Met Glu Asn Leu Gly Leu
                 125                 130                 135

 Ala Gln Asn Cys Thr Ile Ser Ile Gln Asp Tyr Glu Val Phe Arg
                 140                 145                 150

 Cys Glu Asp Ser Leu Asp Glu Arg Lys Ile Lys Gly Val Ile Glu
                 155                 160                 165

 Leu Arg Lys Ser Leu Leu Ser Ala Leu Arg Thr Tyr Glu Pro Tyr
                 170                 175                 180

 Gly Ser Leu Val Gln Gln Ile Arg Ile Leu Leu Leu Gly Pro Ile
                 185                 190                 195

 Gly Ala Gly Lys Ser Ser Phe Phe Asn Ser Val Arg Ser Val Phe
                 200                 205                 210

 Gln Gly His Val Thr His Gln Ala Leu Val Gly Thr Asn Thr Thr
                 215                 220                 225

 Gly Ile Ser Glu Lys Tyr Arg Thr Tyr Ser Ile Arg Asp Gly Lys
                 230                 235                 240

 Asp Gly Lys Tyr Leu Pro Phe Ile Leu Cys Asp Ser Leu Gly Leu
                 245                 250                 255

 Ser Glu Lys Glu Gly Gly Leu Cys Arg Asp Asp Ile Phe Tyr Ile
                 260                 265                 270

 Leu Asn Gly Asn Ile Arg Asp Arg Tyr Gln Phe Asn Pro Met Glu
                 275                 280                 285

 Ser Ile Lys Leu Asn His His Asp Tyr Ile Asp Ser Pro Ser Leu
                 290                 295                 300

 Lys Asp Arg Ile His Cys Val Ala Phe Val Phe Asp Ala Ser Ser
                 305                 310                 315

 Ile Gln Tyr Phe Ser Ser Gln Met Ile Val Lys Ile Lys Arg Ile
                 320                 325                 330

 Arg Arg Glu Leu Val Asn Ala Gly Val Val His Val Ala Leu Leu
                 335                 340                 345

 Thr His Val Asp Ser Met Asp Leu Ile Thr Lys Gly Asp Leu Ile
                 350                 355                 360

 Glu Ile Glu Arg Cys Glu Pro Val Arg Ser Lys Leu Glu Glu Val
                 365                 370                 375

 Gln Arg Lys Leu Gly Phe Ala Leu Ser Asp Ile Ser Val Val Ser
                 380                 385                 390

 Asn Tyr Ser Ser Glu Trp Glu Leu Asp Pro Val Lys Asp Val Leu
                 395                 400                 405

 Ile Leu Ser Ala Leu Arg Arg Met Leu Trp Ala Ala Asp Asp Phe
                 410                 415                 420

 Leu Glu Asp Leu Pro Phe Glu Gln Ile Gly Asn Leu Arg Glu Glu
                 425                 430                 435

 Ile Ile Asn Cys Ala Gln Gly Lys Lys
                 440

<210> 6030
<211> 2140
<212> DNA
<213> Homo sapien

<400> 6030
 agctgaggtg tgagcagctg ccgaagtcag ttccttgtgg agccggagct 50

 gggcgcggat tcgccgaggc accgaggcac tcagaggagg cgccatgtca 100

 gaaccggctg gggatgtccg tcagaaccca tgcggcagca aggcctgccg 150

 ccgcctcttc ggcccagtgg acagcgagca gctgagccgc gactgtgatg 200

 cgctaatggc gggctgcatc caggaggccc gtgagcgatg gaacttcgac 250

 tttgtcaccg agacaccact ggagggtgac ttcgcctggg agcgtgtgcg 300

 gggccttggc ctgcccaagc tctaccttcc cacggggccc cggcgaggcc 350

 gggatgagtt gggaggaggc aggcggcctg gcacctcacc tgctctgctg 400

 caggggacag cagaggaaga ccatgtggac ctgtcactgt cttgtaccct 450

 tgtgcctcgc tcaggggagc aggctgaagg gtccccaggt ggacctggag 500

 actctcaggg tcgaaaacgg cggcagacca gcatgacaga tttctaccac 550

 tccaaacgcc ggctgatctt ctccaagagg aagccctaat ccgcccacag 600

 gaagcctgca gtcctggaag cgcgagggcc tcaaaggccc gctctacatc 650

 ttctgcctta gtctcagttt gtgtgtctta attattattt gtgttttaat 700

 ttaaacacct cctcatgtac ataccctggc cgccccctgc cccccagcct 750

 ctggcattag aattatttaa acaaaaacta ggcggttgaa tgagaggttc 800

 ctaagagtgc tgggcatttt tattttatga aatactattt aaagcctcct 850

 catcccgtgt tctccttttc ctctctcccg gaggttgggt gggccggctt 900

 catgccagct acttcctcct ccccacttgt ccgctgggtg gtaccctctg 950

 gaggggtgtg gctccttccc atcgctgtca caggcggtta tgaaattcac 1000

 cccctttcct ggacactcag acctgaattc tttttcattt gagaagtaaa 1050

 cagatggcac tttgaagggg cctcaccgag tgggggcatc atcaaaaact 1100

 ttggagtccc ctcacctcct ctaaggttgg gcagggtgac cctgaagtga 1150

 gcacagccta gggctgagct ggggacctgg taccctcctg gctcttgata 1200

 cccccctctg tcttgtgaag gcagggggaa ggtggggtac tggagcagac 1250

 caccccgcct gccctcatgg cccctctgac ctgcactggg gagcccgtct 1300

 cagtgttgag ccttttccct ctttggctcc cctgtacctt ttgaggagcc 1350

 ccagcttacc cttcttctcc agctgggctc tgcaattccc ctctgctgct 1400

 gtccctcccc cttgtctttc ccttcagtac cctctcatgc tccaggtggc 1450

 tctgaggtgc ctgtcccacc cccaccccca gctcaatgga ctggaagggg 1500

 aagggacaca caagaagaag ggcaccctag ttctacctca ggcagctcaa 1550

 gcagcgaccg ccccctcctc tagctgtggg ggtgagggtc ccatgtggtg 1600

 gcacaggccc ccttgagtgg ggttatctct gtgttagggg tatatgatgg 1650

 gggagtagat ctttctagga gggagacact ggcccctcaa atcgtccagc 1700

 gaccttcctc atccacccca tccctcccca gttcattgca ctttgattag 1750

 cagcggaaca aggagtcaga cattttaaga tggtggcagt agaggctatg 1800

 gacagggcat gccacgtggg ctcatatggg gctgggagta gttgtctttc 1850

 ctggcactaa cgttgagccc ctggaggcac tgaagtgctt agtgtacttg 1900

 gagtattggg gtctgacccc aaacaccttc cagctcctgt aacatactgg 1950

 cctggactgt tttctctcgg ctccccatgt gtcctggttc ccgtttctcc 2000

 acctagactg taaacctctc gagggcaggg accacaccct gtactgttct 2050

 gtgtctttca cagctcctcc cacaatgctg aatatacagc aggtgctcaa 2100

 taaatgattc ttagtgactt taaaaaaaaa aaaaaaaaaa 2140

<210> 6031
<211> 164
<212> PRT
<213> Homo sapien

<400> 6031
 Met Ser Glu Pro Ala Gly Asp Val Arg Gln Asn Pro Cys Gly Ser
   1               5                  10                  15

 Lys Ala Cys Arg Arg Leu Phe Gly Pro Val Asp Ser Glu Gln Leu
                  20                  25                  30

 Ser Arg Asp Cys Asp Ala Leu Met Ala Gly Cys Ile Gln Glu Ala
                  35                  40                  45

 Arg Glu Arg Trp Asn Phe Asp Phe Val Thr Glu Thr Pro Leu Glu
                  50                  55                  60

 Gly Asp Phe Ala Trp Glu Arg Val Arg Gly Leu Gly Leu Pro Lys
                  65                  70                  75

 Leu Tyr Leu Pro Thr Gly Pro Arg Arg Gly Arg Asp Glu Leu Gly
                  80                  85                  90

 Gly Gly Arg Arg Pro Gly Thr Ser Pro Ala Leu Leu Gln Gly Thr
                  95                 100                 105

 Ala Glu Glu Asp His Val Asp Leu Ser Leu Ser Cys Thr Leu Val
                 110                 115                 120

 Pro Arg Ser Gly Glu Gln Ala Glu Gly Ser Pro Gly Gly Pro Gly
                 125                 130                 135

 Asp Ser Gln Gly Arg Lys Arg Arg Gln Thr Ser Met Thr Asp Phe
                 140                 145                 150

 Tyr His Ser Lys Arg Arg Leu Ile Phe Ser Lys Arg Lys Pro
                 155                 160

<210> 6032
<211> 717
<212> DNA
<213> Mus musculus

<400> 6032
 agagcgatca tgtcgcacaa acaaatttac tattcggaca aatacgacga 50

 cgaggagttt gagtatcgac atgtcatgct gcccaaggac atagccaagc 100

 tggtccctaa aacccatctg atgtctgaat ctgaatggag gaatcttggc 150

 gttcagcaga gtcagggatg ggtccattat atgatccatg aaccagaacc 200

 tcacatcttg ctgttccggc gcccactacc caagaaacca aagaaatgaa 250

 gctggcaagc tacttttcag cctcaagctt tacacagctg tccttacttc 300

 ctaacatctt tctgataaca ttattatgtt gccttcttgt ttctcacttt 350

 gatatttaaa agatgttcaa tacactgttt gaatgtgctg gtaactgctt 400

 tgcttcttga gtagagccac caccaccata gcccagccag atgagtgctc 450

 tgtggaccca cagcctaagc tgagtgtgac cccagaagcc acgatgtgct 500

 ctgtatccag aacacacttg gcagatggag gaagcatctg agtttgagac 550

 catggctgtt acagggatca tgtaaacttg ctgtttttgt tttttctgcc 600

 gggtgttgta tgtgtggtga cttgcggatt tatgtttcag tgtactggaa 650

 actttccatt ttattcaaga aatctgttca tgttaaaagc cttgattaaa 700

 gaggaagttt ttataat 717

<210> 6033
<211> 79
<212> PRT
<213> Mus musculus

<400> 6033
 Met Ser His Lys Gln Ile Tyr Tyr Ser Asp Lys Tyr Asp Asp Glu
   1               5                  10                  15

 Glu Phe Glu Tyr Arg His Val Met Leu Pro Lys Asp Ile Ala Lys
                  20                  25                  30

 Leu Val Pro Lys Thr His Leu Met Ser Glu Ser Glu Trp Arg Asn
                  35                  40                  45

 Leu Gly Val Gln Gln Ser Gln Gly Trp Val His Tyr Met Ile His
                  50                  55                  60

 Glu Pro Glu Pro His Ile Leu Leu Phe Arg Arg Pro Leu Pro Lys
                  65                  70                  75

 Lys Pro Lys Lys


<210> 6034
<211> 4104
<212> DNA
<213> Homo sapien

<400> 6034
 ctgcaggtta ttcagcgata gttatgacct cccggttacg tgcgttgggt 50

 ggaagaatta ataatatacg cacctcggag ttacccaaag agaaaactcg 100

 atcagaagtc atttgcagca tccacttttt agatggcgtg gtacagacct 150

 ttaaagttac taaacaagac actggccagg ttcttctgga tatggtgcac 200

 aaccacctgg gtgtgactga aaaggaatat tttggtttac agcatgatga 250

 cgactccgtg gactctccta gatggctgga agcaagcaaa gccatcagga 300

 agcagttaaa aggaggtttc ccctgtaccc tgcattttcg agtaagattt 350

 tttatacctg atcccaacac actgcagcaa gaacaaacca ggcacttgta 400

 tttcttacaa ctgaagatgg atatttgcga aggaaggtta acctgccctc 450

 ttaactcagc agtggttcta gcgtcctatg ccgtacaatc tcattttgga 500

 gactataatt cttccataca tcatccaggc tatctttccg atagtcactt 550

 tatacccgat caaaatgagg actttttaac aaaagtcgaa tctctgcatg 600

 agcagcacag tgggctaaaa caatcagaag cagaatcctg ctatatcaac 650

 atagcgcgga ccctcgactt ctatggagta gaactgcaca gtggtaggga 700

 tctgcacaat ttagacctaa tgattggaat tgcttccgcg ggtgttgctg 750

 tgtaccgaaa atacatttgc acaagtttct atccttgggt gaacattctc 800

 aaaatttctt tcaaaaggaa aaagttcttc atacatcagc gacagaaaca 850

 ggctgaatcc agggaacata ttgtggcctt caacatgctg aattaccgat 900

 cttgcaaaaa cttgtggaaa tcctgtgttg agcaccatac gttctttcag 950

 gcaaagaagc tactacctca ggaaaagaat gttctgtctc agtactggac 1000

 tatgggctct cggaacacca aaaagtcggt aaataaccaa tattgcaaaa 1050

 aggtgattgg cgggatggtg tggaacccag ccatgcggag atccttatca 1100

 gtggagcact tagaaaccaa gagtctgcct tctcgttccc ctcccattac 1150

 tcccaactgg cgaagtcctc ggctccggca cgaaatccga aagccacgcc 1200

 actcttctgc agataacctt gcaaatgaaa tgacctacat cacggaaacg 1250

 gaagatgtat tttacacgta caagggctct ctggcccctc aagacagcga 1300

 ttctgaagtt tctcagaacc gaagcccgca ccaagagagt ttatccgaga 1350

 acaatccggc acaaagctac ctgacccaga agtcatccag ttctgtgtct 1400

 ccatcttcaa atgctccagg ctcctgctca cctgacggcg ttgatcagca 1450

 gctcttagat gacttccaca gggtgaccaa agggggctcc accgaggacg 1500

 ccagccagta ctactgtgac aagaatgata atggtgacag ctacttagtc 1550

 ttgatccgta tcacaccaga tgaagatgga aaatttggat ttaatcttaa 1600

 gggaggagtg gatcaaaaga tgcctcttgt ggtatcaagg ataaacccag 1650

 agtcacctgc ggacacctgc attcctaagc tgaacgaagg ggatcaaatc 1700

 gtgttaatca atggccggga catctcagaa cacacgcatg accaagtggt 1750

 gatgttcatc aaagccagcc gggagtccca ctcacgggag ctggccctgg 1800

 tgatcaggag gagagctgtc cgctcatttg ctgacttcaa gtctgaagat 1850

 gaactgaacc agcttttccc cgaagccatt ttccccatgt gtccggaggg 1900

 tggggacact ttggagggat ccatggcaca gctaaagaag ggcctcgaaa 1950

 gcgggacggt gctgatccag tttgagcaac tctacagaaa aaagccaggt 2000

 ttggccatca cgtttgcaaa gctgcctcaa aatttggaca aaaaccgata 2050

 taaagatgtg ctgccttatg acaccacccg ggtattattg cagggaaatg 2100

 aagattatat taatgcaagt tacgtgaaca tggaaattcc tgctgctaac 2150

 cttgtgaaca agtacatcgc cactcagggg cccctgccgc atacctgtgc 2200

 acagttttgg caggttgtct gggatcagaa gttgtcactc attgtcatgt 2250

 tgacgactct cacagaacga gggcggacca aatgtcacca gtactggcca 2300

 gatccccccg acgtcatgaa ccacggcggc tttcacatcc agtgtcagtc 2350

 agaggactgc accatcgcct atgtgtcccg agaaatgctg gtcacaaaca 2400

 cccagaccgg ggaagaacac acagtgacac atctccagta cgtcgcatgg 2450

 cctgaccacg gtgtgcccga tgactcctcc gactttctgg aatttgtaaa 2500

 ctatgtgagg tctctgagag tggacagcga gcctctccta gttcactgca 2550

 gtgctggaat aggtcgaacc ggtgtgttgg tcactatgga aacagccatg 2600

 tgcctaactg agaggaacct gcccatttac ccactggata ttgtccgaaa 2650

 aatgcgagac cagcgcgcca tgatggtgca gacatcaagc cagtacaagt 2700

 ttgtgtgtga agcgattctt cgtgtgtatg aagaaggttt agtccaaatg 2750

 ctggatccta gttaagacaa ctgtgaaaaa gttcattcct ctttcccaag 2800

 ggcatcctcc ttgaaagagg aggacagacc tctctggaag cagcaagagg 2850

 aaccagtagc tgtgggaaag gaatgggcac ctctgaaccc aggcacttta 2900

 aacttctata gaaaagatat cgtgtacata ggaactggtg tagataagca 2950

 tgcaattatg gcatcattta ggcctgtatt tctatggaaa gatacaaaaa 3000

 ggatctcagt ttggggcctg tcctaatgcc ttcttcccta acatcaccac 3050

 acacacccct gtcggcatcc tggagcaatt gagaccggac acccacagag 3100

 ctgttgtcct cccagcaaca agatggtgtg gttatcttgg gtcatttgga 3150

 tgttttgttt gtttctgtgt gtcagactgt aagggctgag ctttctgtgc 3200

 ttctaggtgg agctggaaca attcagattc acccgccctg atgctaagga 3250

 aaccctgacg tatgtactag atggcagggc actgggggtc aggctgaagg 3300

 ctgagcaaca cctctctgcc ctccctccct ttgtcccatc tcccagcgac 3350

 ttccaatatt catgtttctg agaattgtgt ccctcttcag gttccctctt 3400

 ggtgcctaac ctggattagt aatgtgcatt caggtgaatt ttcagctgag 3450

 gctctgagaa ctggtactct cagtgtgttc tggtcatctt gtggcttagt 3500

 tgtagaagca ggtgtgtctc ttgcctctgc ttgcctccta ctgcacactc 3550

 agcacccagg actggaatca ccgactactg aatctcctac atgtattgct 3600

 gctacttcaa gctcctccac ttgaaacctt atgattttcc caaggggaga 3650

 tgggacagtg tcatctaaat attccgaatg tttggccttc tgagaaaaga 3700

 gcttctagta attgaaccat gggaaaccca gcttctggag ggttggccgt 3750

 ggggctgtgt acatgtgtgt gcccaggggt gagtgtttct caggattcct 3800

 aacgattcaa attaccgttg agtatatata aagaatgagt ctctgtatgg 3850

 aagaacaaat gtgtgcattc acccccagtc acaatggtct ccattgcatt 3900

 tcaaaggaga ggatcagact atctgaatat aaacacaatc tgatgttaat 3950

 ttattctaag aacaccatca ttttgattgt cctaaagaat tctgcctttg 4000

 tgaataccgt gttaaatttt tttaaatttg tgacaggatt gtagcaaatt 4050

 attatttaag gaaaataaat tgtgtaaaca tttaaaaaaa aaaaaaaaaa 4100

 aaaa 4104

<210> 6035
<211> 913
<212> PRT
<213> Homo sapien

<400> 6035
 Met Thr Ser Arg Leu Arg Ala Leu Gly Gly Arg Ile Asn Asn Ile
   1               5                  10                  15

 Arg Thr Ser Glu Leu Pro Lys Glu Lys Thr Arg Ser Glu Val Ile
                  20                  25                  30

 Cys Ser Ile His Phe Leu Asp Gly Val Val Gln Thr Phe Lys Val
                  35                  40                  45

 Thr Lys Gln Asp Thr Gly Gln Val Leu Leu Asp Met Val His Asn
                  50                  55                  60

 His Leu Gly Val Thr Glu Lys Glu Tyr Phe Gly Leu Gln His Asp
                  65                  70                  75

 Asp Asp Ser Val Asp Ser Pro Arg Trp Leu Glu Ala Ser Lys Ala
                  80                  85                  90

 Ile Arg Lys Gln Leu Lys Gly Gly Phe Pro Cys Thr Leu His Phe
                  95                 100                 105

 Arg Val Arg Phe Phe Ile Pro Asp Pro Asn Thr Leu Gln Gln Glu
                 110                 115                 120

 Gln Thr Arg His Leu Tyr Phe Leu Gln Leu Lys Met Asp Ile Cys
                 125                 130                 135

 Glu Gly Arg Leu Thr Cys Pro Leu Asn Ser Ala Val Val Leu Ala
                 140                 145                 150

 Ser Tyr Ala Val Gln Ser His Phe Gly Asp Tyr Asn Ser Ser Ile
                 155                 160                 165

 His His Pro Gly Tyr Leu Ser Asp Ser His Phe Ile Pro Asp Gln
                 170                 175                 180

 Asn Glu Asp Phe Leu Thr Lys Val Glu Ser Leu His Glu Gln His
                 185                 190                 195

 Ser Gly Leu Lys Gln Ser Glu Ala Glu Ser Cys Tyr Ile Asn Ile
                 200                 205                 210

 Ala Arg Thr Leu Asp Phe Tyr Gly Val Glu Leu His Ser Gly Arg
                 215                 220                 225

 Asp Leu His Asn Leu Asp Leu Met Ile Gly Ile Ala Ser Ala Gly
                 230                 235                 240

 Val Ala Val Tyr Arg Lys Tyr Ile Cys Thr Ser Phe Tyr Pro Trp
                 245                 250                 255

 Val Asn Ile Leu Lys Ile Ser Phe Lys Arg Lys Lys Phe Phe Ile
                 260                 265                 270

 His Gln Arg Gln Lys Gln Ala Glu Ser Arg Glu His Ile Val Ala
                 275                 280                 285

 Phe Asn Met Leu Asn Tyr Arg Ser Cys Lys Asn Leu Trp Lys Ser
                 290                 295                 300

 Cys Val Glu His His Thr Phe Phe Gln Ala Lys Lys Leu Leu Pro
                 305                 310                 315

 Gln Glu Lys Asn Val Leu Ser Gln Tyr Trp Thr Met Gly Ser Arg
                 320                 325                 330

 Asn Thr Lys Lys Ser Val Asn Asn Gln Tyr Cys Lys Lys Val Ile
                 335                 340                 345

 Gly Gly Met Val Trp Asn Pro Ala Met Arg Arg Ser Leu Ser Val
                 350                 355                 360

 Glu His Leu Glu Thr Lys Ser Leu Pro Ser Arg Ser Pro Pro Ile
                 365                 370                 375

 Thr Pro Asn Trp Arg Ser Pro Arg Leu Arg His Glu Ile Arg Lys
                 380                 385                 390

 Pro Arg His Ser Ser Ala Asp Asn Leu Ala Asn Glu Met Thr Tyr
                 395                 400                 405

 Ile Thr Glu Thr Glu Asp Val Phe Tyr Thr Tyr Lys Gly Ser Leu
                 410                 415                 420

 Ala Pro Gln Asp Ser Asp Ser Glu Val Ser Gln Asn Arg Ser Pro
                 425                 430                 435

 His Gln Glu Ser Leu Ser Glu Asn Asn Pro Ala Gln Ser Tyr Leu
                 440                 445                 450

 Thr Gln Lys Ser Ser Ser Ser Val Ser Pro Ser Ser Asn Ala Pro
                 455                 460                 465

 Gly Ser Cys Ser Pro Asp Gly Val Asp Gln Gln Leu Leu Asp Asp
                 470                 475                 480

 Phe His Arg Val Thr Lys Gly Gly Ser Thr Glu Asp Ala Ser Gln
                 485                 490                 495

 Tyr Tyr Cys Asp Lys Asn Asp Asn Gly Asp Ser Tyr Leu Val Leu
                 500                 505                 510

 Ile Arg Ile Thr Pro Asp Glu Asp Gly Lys Phe Gly Phe Asn Leu
                 515                 520                 525

 Lys Gly Gly Val Asp Gln Lys Met Pro Leu Val Val Ser Arg Ile
                 530                 535                 540

 Asn Pro Glu Ser Pro Ala Asp Thr Cys Ile Pro Lys Leu Asn Glu
                 545                 550                 555

 Gly Asp Gln Ile Val Leu Ile Asn Gly Arg Asp Ile Ser Glu His
                 560                 565                 570

 Thr His Asp Gln Val Val Met Phe Ile Lys Ala Ser Arg Glu Ser
                 575                 580                 585

 His Ser Arg Glu Leu Ala Leu Val Ile Arg Arg Arg Ala Val Arg
                 590                 595                 600

 Ser Phe Ala Asp Phe Lys Ser Glu Asp Glu Leu Asn Gln Leu Phe
                 605                 610                 615

 Pro Glu Ala Ile Phe Pro Met Cys Pro Glu Gly Gly Asp Thr Leu
                 620                 625                 630

 Glu Gly Ser Met Ala Gln Leu Lys Lys Gly Leu Glu Ser Gly Thr
                 635                 640                 645

 Val Leu Ile Gln Phe Glu Gln Leu Tyr Arg Lys Lys Pro Gly Leu
                 650                 655                 660

 Ala Ile Thr Phe Ala Lys Leu Pro Gln Asn Leu Asp Lys Asn Arg
                 665                 670                 675

 Tyr Lys Asp Val Leu Pro Tyr Asp Thr Thr Arg Val Leu Leu Gln
                 680                 685                 690

 Gly Asn Glu Asp Tyr Ile Asn Ala Ser Tyr Val Asn Met Glu Ile
                 695                 700                 705

 Pro Ala Ala Asn Leu Val Asn Lys Tyr Ile Ala Thr Gln Gly Pro
                 710                 715                 720

 Leu Pro His Thr Cys Ala Gln Phe Trp Gln Val Val Trp Asp Gln
                 725                 730                 735

 Lys Leu Ser Leu Ile Val Met Leu Thr Thr Leu Thr Glu Arg Gly
                 740                 745                 750

 Arg Thr Lys Cys His Gln Tyr Trp Pro Asp Pro Pro Asp Val Met
                 755                 760                 765

 Asn His Gly Gly Phe His Ile Gln Cys Gln Ser Glu Asp Cys Thr
                 770                 775                 780

 Ile Ala Tyr Val Ser Arg Glu Met Leu Val Thr Asn Thr Gln Thr
                 785                 790                 795

 Gly Glu Glu His Thr Val Thr His Leu Gln Tyr Val Ala Trp Pro
                 800                 805                 810

 Asp His Gly Val Pro Asp Asp Ser Ser Asp Phe Leu Glu Phe Val
                 815                 820                 825

 Asn Tyr Val Arg Ser Leu Arg Val Asp Ser Glu Pro Leu Leu Val
                 830                 835                 840

 His Cys Ser Ala Gly Ile Gly Arg Thr Gly Val Leu Val Thr Met
                 845                 850                 855

 Glu Thr Ala Met Cys Leu Thr Glu Arg Asn Leu Pro Ile Tyr Pro
                 860                 865                 870

 Leu Asp Ile Val Arg Lys Met Arg Asp Gln Arg Ala Met Met Val
                 875                 880                 885

 Gln Thr Ser Ser Gln Tyr Lys Phe Val Cys Glu Ala Ile Leu Arg
                 890                 895                 900

 Val Tyr Glu Glu Gly Leu Val Gln Met Leu Asp Pro Ser
                 905                 910

<210> 6036
<211> 1683
<212> DNA
<213> Homo sapien

<400> 6036
 gggcgggggt acctgtaccc acgtagtcgc cggttaccga tcggactaag 50

 ttccagaagc aagagataaa gtaataatgg gtactgtggg gaaaaacaca 100

 gaagaacaat tcggtaatat agtggtgatt tacaagtcaa gttaaaatgt 150

 ccccagaagt ggccttgaac cgaatatctc caatgctctc ccctttcata 200

 tctagcgtgg tccggaatgg aaaagtggga ctggatgcta caaactgttt 250

 gaggataact gacttaaaat ctggctgcac atcattgact cctgggccca 300

 actgtgaccg atttaaactg cacataccat atgctggaga gacattaaag 350

 tgggatatca ttttcaatgc ccaataccca gaactgcctc ccgattttat 400

 ctttggagaa gatgctgaat tcctgccaga cccctcagct ttgcagaatc 450

 ttgcctcctg gaatccttca aatcctgaat gtctcttact tgtggtgaag 500

 gaacttgtgc aacaatatca ccaattccaa tgtagccgcc tccgggagag 550

 ctcccgcctc atgtttgaat accagacatt actggaggag ccacagtatg 600

 gagagaacat ggaaatttat gctgggaaaa aaaacaactg gactggtgaa 650

 ttttcagctc gtttcctttt gaagctgccc gtagatttca gcaatatccc 700

 cacatacctt ctcaaggatg taaatgaaga ccctggagaa gatgtggccc 750

 tcctctctgt tagttttgag gacactgaag ccacccaggt gtaccccaag 800

 ctgtacttgt cacctcgaat tgagcatgca cttggaggct cctcagctct 850

 tcatatccca gcttttccag gaggaggatg tctcattgat tacgttcctc 900

 aagtatgcca cctgctcacc aacaaggtgc agtacgtgat tcaagggtat 950

 cacaaaagaa gagagtatat tgctgctttt ctcagtcact ttggcacagg 1000

 tgtcgtggaa tatgatgcag aaggctttac aaaactcact ctgctgctga 1050

 tgtggaaaga tttttgtttt cttgtacaca ttgacctgcc tctgtttttc 1100

 cctcgagacc agccaactct cacatttcag tccgtttatc actttaccaa 1150

 cagtggacag ctttactccc aggcccaaaa aaattatccg tacagcccca 1200

 gatgggatgg aaatgaaatg gccaaaagag caaaggctta tttcaaaacc 1250

 tttgtccctc agttccagga ggcagcattt gccaatggaa agctctagga 1300

 aacaccagtc ttgagaggtg gccagccaga ctgcctgtcc acatgcgtgt 1350

 cagcacatac agccgcttcc tggaagccgc ctggaatgtc ttcacggcag 1400

 cgttttgctc acacagcagc ttttgcacgc cccaggcagc cccgactgct 1450

 gaaatccaac ttgagctggc tggtggtccc tggatcctag agcccttcac 1500

 ttcgggttac tccctctttc ttgcctctat ttcttagttg gaagaaataa 1550

 actcacaaat tatggtgcag taattttccg gggaaagtaa agcctcagga 1600

 atgcccacgc ctttcttcca aagcctttgt ctctgagacc tcttaagttc 1650

 taagattaaa tgcccctcgc tgttcttcct ctg 1683

<210> 6037
<211> 383
<212> PRT
<213> Homo sapien

<400> 6037
 Met Ser Pro Glu Val Ala Leu Asn Arg Ile Ser Pro Met Leu Ser
   1               5                  10                  15

 Pro Phe Ile Ser Ser Val Val Arg Asn Gly Lys Val Gly Leu Asp
                  20                  25                  30

 Ala Thr Asn Cys Leu Arg Ile Thr Asp Leu Lys Ser Gly Cys Thr
                  35                  40                  45

 Ser Leu Thr Pro Gly Pro Asn Cys Asp Arg Phe Lys Leu His Ile
                  50                  55                  60

 Pro Tyr Ala Gly Glu Thr Leu Lys Trp Asp Ile Ile Phe Asn Ala
                  65                  70                  75

 Gln Tyr Pro Glu Leu Pro Pro Asp Phe Ile Phe Gly Glu Asp Ala
                  80                  85                  90

 Glu Phe Leu Pro Asp Pro Ser Ala Leu Gln Asn Leu Ala Ser Trp
                  95                 100                 105

 Asn Pro Ser Asn Pro Glu Cys Leu Leu Leu Val Val Lys Glu Leu
                 110                 115                 120

 Val Gln Gln Tyr His Gln Phe Gln Cys Ser Arg Leu Arg Glu Ser
                 125                 130                 135

 Ser Arg Leu Met Phe Glu Tyr Gln Thr Leu Leu Glu Glu Pro Gln
                 140                 145                 150

 Tyr Gly Glu Asn Met Glu Ile Tyr Ala Gly Lys Lys Asn Asn Trp
                 155                 160                 165

 Thr Gly Glu Phe Ser Ala Arg Phe Leu Leu Lys Leu Pro Val Asp
                 170                 175                 180

 Phe Ser Asn Ile Pro Thr Tyr Leu Leu Lys Asp Val Asn Glu Asp
                 185                 190                 195

 Pro Gly Glu Asp Val Ala Leu Leu Ser Val Ser Phe Glu Asp Thr
                 200                 205                 210

 Glu Ala Thr Gln Val Tyr Pro Lys Leu Tyr Leu Ser Pro Arg Ile
                 215                 220                 225

 Glu His Ala Leu Gly Gly Ser Ser Ala Leu His Ile Pro Ala Phe
                 230                 235                 240

 Pro Gly Gly Gly Cys Leu Ile Asp Tyr Val Pro Gln Val Cys His
                 245                 250                 255

 Leu Leu Thr Asn Lys Val Gln Tyr Val Ile Gln Gly Tyr His Lys
                 260                 265                 270

 Arg Arg Glu Tyr Ile Ala Ala Phe Leu Ser His Phe Gly Thr Gly
                 275                 280                 285

 Val Val Glu Tyr Asp Ala Glu Gly Phe Thr Lys Leu Thr Leu Leu
                 290                 295                 300

 Leu Met Trp Lys Asp Phe Cys Phe Leu Val His Ile Asp Leu Pro
                 305                 310                 315

 Leu Phe Phe Pro Arg Asp Gln Pro Thr Leu Thr Phe Gln Ser Val
                 320                 325                 330

 Tyr His Phe Thr Asn Ser Gly Gln Leu Tyr Ser Gln Ala Gln Lys
                 335                 340                 345

 Asn Tyr Pro Tyr Ser Pro Arg Trp Asp Gly Asn Glu Met Ala Lys
                 350                 355                 360

 Arg Ala Lys Ala Tyr Phe Lys Thr Phe Val Pro Gln Phe Gln Glu
                 365                 370                 375

 Ala Ala Phe Ala Asn Gly Lys Leu
                 380

<210> 6038
<211> 1656
<212> DNA
<213> Mus musculus

<400> 6038
 cgcccctgct ctcgcgccgg cgtcggctgc gtctccggcg tttgaattgc 50

 gcttccgcca tctttccagc ctcagtcgga cgggcgcgga ggcgcttctg 100

 gaaggaacgc cgcgatggct gcgcagggag agccccaggt ccagttcaaa 150

 cttgtattgg ttggtgatgg tggtactgga aaaacgacct tcgtgaaacg 200

 tcatttgact ggtgaatttg agaagaagta tgtagccacc ttgggtgttg 250

 aggttcatcc cctagtgttc cacaccaaca gaggacctat taagttcaat 300

 gtatgggaca cagccggcca ggagaaattc ggtggactga gagatggcta 350

 ttatatccaa gcccagtgtg ccatcataat gtttgatgta acatcgagag 400

 ttacttacaa gaatgtgcct aactggcata gagatctggt acgagtgtgt 450

 gaaaacatcc ccattgtgtt gtgtggcaac aaagtggata ttaaggacag 500

 gaaagtgaag gcgaaatcca ttgtcttcca ccgaaagaag aatcttcagt 550

 actacgacat ttctgccaaa agtaactaca actttgaaaa gcccttcctc 600

 tggcttgcta ggaagctcat tggagaccct aacttggaat ttgttgccat 650

 gcctgctctc gccccaccag aagttgtcat ggacccagct ttggcagcac 700

 agtatgagca cgacttagag gttgctcaga caactgctct cccggatgag 750

 gatgatgacc tgtgagaatg aagctggagc ccagcgtcag aagtctagtt 800

 ttataggcag ctgtcctgtg atgtcagcgg tgcagcgtgt gtgccacctc 850

 attattatct agctaagcgg aacatgtgct ttatctgtgg gatgctgaag 900

 gagatgagtg ggcttcggag tgaatgtggc agtttaaaaa ataacttcat 950

 tgtttggacc tgcatattta gctgtttgga cgcagttgat tccttgagtt 1000

 tcatatataa gactgctgca gtcacatcac aatattcagt ggtgaaatct 1050

 tgtttgttac tgtcattccc attccttttc tttagaatca gaataaagtt 1100

 gtatttcaaa tatctaagca agtgaactca tcccttgttt ataaatagca 1150

 tttggaaacc actaaagtag ggaagtttta tgccatgtta atatttgaat 1200

 tgccttgctt ttatcactta atttgaaatc tattgggtta atttctccct 1250

 atgtttattt ttgtacattt gagccatgtc acacaaactg atgatgacag 1300

 gtcagcagta ttctatttgg ttagaagggt tacatggtgt aaatattagt 1350

 gcagttaagc taaagcagtg tttgctccac cttcatattg gctaggtagg 1400

 gtcacctagg gaagcacttg ctcaaaatct gtgacctgtc agaataaaaa 1450

 tgtggtttgt acatatcaaa tagatatttt aagggtaata ttttctttta 1500

 tggcaaaagt aatcatgttt taatgtagaa cctcaaacag gatggaacat 1550

 cagtggatgg caggaggttg ggaattcttg ctgttaaaaa taattacaaa 1600

 ttttgcactt tttgtttgaa tgttagatgc ttagtgtgaa gttgatacgc 1650

 aagccg 1656

<210> 6039
<211> 216
<212> PRT
<213> Mus musculus

<400> 6039
 Met Ala Ala Gln Gly Glu Pro Gln Val Gln Phe Lys Leu Val Leu
   1               5                  10                  15

 Val Gly Asp Gly Gly Thr Gly Lys Thr Thr Phe Val Lys Arg His
                  20                  25                  30

 Leu Thr Gly Glu Phe Glu Lys Lys Tyr Val Ala Thr Leu Gly Val
                  35                  40                  45

 Glu Val His Pro Leu Val Phe His Thr Asn Arg Gly Pro Ile Lys
                  50                  55                  60

 Phe Asn Val Trp Asp Thr Ala Gly Gln Glu Lys Phe Gly Gly Leu
                  65                  70                  75

 Arg Asp Gly Tyr Tyr Ile Gln Ala Gln Cys Ala Ile Ile Met Phe
                  80                  85                  90

 Asp Val Thr Ser Arg Val Thr Tyr Lys Asn Val Pro Asn Trp His
                  95                 100                 105

 Arg Asp Leu Val Arg Val Cys Glu Asn Ile Pro Ile Val Leu Cys
                 110                 115                 120

 Gly Asn Lys Val Asp Ile Lys Asp Arg Lys Val Lys Ala Lys Ser
                 125                 130                 135

 Ile Val Phe His Arg Lys Lys Asn Leu Gln Tyr Tyr Asp Ile Ser
                 140                 145                 150

 Ala Lys Ser Asn Tyr Asn Phe Glu Lys Pro Phe Leu Trp Leu Ala
                 155                 160                 165

 Arg Lys Leu Ile Gly Asp Pro Asn Leu Glu Phe Val Ala Met Pro
                 170                 175                 180

 Ala Leu Ala Pro Pro Glu Val Val Met Asp Pro Ala Leu Ala Ala
                 185                 190                 195

 Gln Tyr Glu His Asp Leu Glu Val Ala Gln Thr Thr Ala Leu Pro
                 200                 205                 210

 Asp Glu Asp Asp Asp Leu
                 215

<210> 6040
<211> 2809
<212> DNA
<213> Homo sapien

<400> 6040
 agattcgcgg ccgcgtcgac ggtgcgccca ccggtcccgc cgggcgcccg 50

 cgggacgcgc cgccagggcc ctctccgccg ggggctcggc gctcgcccac 100

 ctcttccaaa tttaaccatt acctaaatcc gaagggaaat gagcaaacct 150

 ctcggattgg gtgtcaaggt ctcctccggg ctggggctga gcaagccctc 200

 ggagtgaccg tgggtgacag cggctccagg gactcttggg gcgcagtggg 250

 gaaagtgccg gaccaccatg ccgcgctcat ttctcgtcaa aagcaagaag 300

 gctcacagct accaccagcc gcgctcccca ggaccagact attccctccg 350

 tttagagaat gtaccggcgc ctagccgagc agacagcact tcaaatgcag 400

 gcggggcgaa agcggagccc cgggaccgtt tgtcccccga atcgcagctg 450

 accgaagccc cagacagagc ctccgcatcc cccagacagc tgcgaagcag 500

 cgtctgcgaa cggagctcgg agtttgagga cttctggagg cccccgtcac 550

 cctccgcgtc tccagcctcg gagaagtcaa tgtgcccatc gctggacgaa 600

 gcccagccct tccccctgcc tttcaaaccg tactcatgga gcggcctggc 650

 gggttctgac ctgcggcacc tggtgcagag ctaccgaccg tgtggggccc 700

 tggagcgtgg cgctggcctg ggcctcttct gtgaacccgc cccggagcct 750

 ggccacccgg ccgcgctgta cggcccgaag cgggctgccg gcggcgcggg 800

 ggccggggcg ccagggaact gcatcgcagg ggccggtgcc accgctggcc 850

 ctggcctagg gctctacggc gacttcgggt ctgcggcagc cgggctgtat 900

 gaaaagccca cggcagcggc gggcttgctg taccccgagc gtggccaccg 950

 gctgcacgca aacaaaggcg ctggcgtcaa ggtggagtcg gagctgctgt 1000

 gcacccgcct gctgctgggc ggcggctcct acaagtgcat caagtgcagc 1050

 aaggtgtttt ccacgccgca cgggctcgag gtgcacgtgc gcaggtccca 1100

 cagcggtacc agaccctttg cctgcgagat gtgcggcaag accttcgggc 1150

 acgcggtgag cctggagcag cacaaagccg tgcactcgca ggaacggagc 1200

 tttgactgta agatctgtgg gaagagcttc aagaggtcat ccacactgtc 1250

 cacacacctg cttatccact cagacactcg gccctacccc tgtcagtact 1300

 gtggcaagag gttccaccag aagtcagaca tgaagaaaca cactttcatc 1350

 cacactggtg agaagcttca caagtgccag gtgtgcggca aggcattcag 1400

 ccagagctcc aacctcatca cccacagccg caaacacaca ggcttcaagc 1450

 ccttcggctg cgacctctgt gggaagggtt tccagaggaa ggtggacctc 1500

 cgaaggcacc gggagacgca gcatgggctc aaatgagcac cctggctggc 1550

 tgcaagcagc agctacacaa cactacagag ggcagcctcc ctgcttgcca 1600

 ccactctgct ccctgcttgc ctccactccc ttctgacttt ccagacccca 1650

 ggtccagtct gcagatccta ccaggttgct cctccttcgc cttacctcct 1700

 ggagctgcca gaagaaatga ggtacctttt caaagtgcag ccgagagtga 1750

 gaaccaagtg actccctagg cttcggacac aaataggctc ctctacacct 1800

 gaagacaaag gcaaagtcaa atggggacca gaataaatct tagaccccac 1850

 agtccttccc atttccagcc ttaatctaca gacaggaatg cccttcaggt 1900

 ttcttccttc ccccttcttg acctacccca gatatttgtg tggaagagga 1950

 ggaatcacca tttacaaggt ggacaaatgc taatattttt atctagaaag 2000

 aagagtgagt gttaactttt atttttttcc ttctgggggg tctgttgact 2050

 cctttctttt gggtgctgcc tataaatctt ggaggaatca tttctcctcc 2100

 tcaaaaactg attcagaaac tgacttgggg aaggaattta atactttgaa 2150

 gtcatgagat gcaccatcga ggctaccccc aagaagaagc agaagagaag 2200

 ttggtaatga gaggggatta gaggtcctcc cttcagtagg gctgtgaaaa 2250

 cctcatcact ggaggtaaaa gcacaagcaa tgcctgtgga caagatgtca 2300

 ttcattcact cagcaaatgt tcatggatca ccggctacca agtaccaggc 2350

 accatgttag gtattgggga agagagactg aagtcacaac ccctgactgc 2400

 tcctcaaaag ctaacggttg cacctccaag tggctgggtc tgttcttact 2450

 cttggaggga attctgagaa gacagcacag aattgtaaac cttccctttt 2500

 gacccttttg gattttatca ggtgtaaaca aaaagctgaa cagttacttc 2550

 aaagatatgt gtgtatattc agttttttat tgttaagctg atattttaaa 2600

 gatttctgag ctagcaggca tgtgggaagg aaggctctgt cttcaactct 2650

 ttgaccctcc atgtgtacca tagagggggg aaaggtggta ttttcacttt 2700

 gatgaggttg gtaaatgttt ttagatcttc tggtaagcat tatgtttgtt 2750

 aatacatatt tattagagtg atgttttaag ttaataaagt attaagagta 2800

 aaaaaaaaa 2809

<210> 6041
<211> 422
<212> PRT
<213> Homo sapien

<400> 6041
 Met Pro Arg Ser Phe Leu Val Lys Ser Lys Lys Ala His Ser Tyr
   1               5                  10                  15

 His Gln Pro Arg Ser Pro Gly Pro Asp Tyr Ser Leu Arg Leu Glu
                  20                  25                  30

 Asn Val Pro Ala Pro Ser Arg Ala Asp Ser Thr Ser Asn Ala Gly
                  35                  40                  45

 Gly Ala Lys Ala Glu Pro Arg Asp Arg Leu Ser Pro Glu Ser Gln
                  50                  55                  60

 Leu Thr Glu Ala Pro Asp Arg Ala Ser Ala Ser Pro Arg Gln Leu
                  65                  70                  75

 Arg Ser Ser Val Cys Glu Arg Ser Ser Glu Phe Glu Asp Phe Trp
                  80                  85                  90

 Arg Pro Pro Ser Pro Ser Ala Ser Pro Ala Ser Glu Lys Ser Met
                  95                 100                 105

 Cys Pro Ser Leu Asp Glu Ala Gln Pro Phe Pro Leu Pro Phe Lys
                 110                 115                 120

 Pro Tyr Ser Trp Ser Gly Leu Ala Gly Ser Asp Leu Arg His Leu
                 125                 130                 135

 Val Gln Ser Tyr Arg Pro Cys Gly Ala Leu Glu Arg Gly Ala Gly
                 140                 145                 150

 Leu Gly Leu Phe Cys Glu Pro Ala Pro Glu Pro Gly His Pro Ala
                 155                 160                 165

 Ala Leu Tyr Gly Pro Lys Arg Ala Ala Gly Gly Ala Gly Ala Gly
                 170                 175                 180

 Ala Pro Gly Asn Cys Ile Ala Gly Ala Gly Ala Thr Ala Gly Pro
                 185                 190                 195

 Gly Leu Gly Leu Tyr Gly Asp Phe Gly Ser Ala Ala Ala Gly Leu
                 200                 205                 210

 Tyr Glu Lys Pro Thr Ala Ala Ala Gly Leu Leu Tyr Pro Glu Arg
                 215                 220                 225

 Gly His Arg Leu His Ala Asn Lys Gly Ala Gly Val Lys Val Glu
                 230                 235                 240

 Ser Glu Leu Leu Cys Thr Arg Leu Leu Leu Gly Gly Gly Ser Tyr
                 245                 250                 255

 Lys Cys Ile Lys Cys Ser Lys Val Phe Ser Thr Pro His Gly Leu
                 260                 265                 270

 Glu Val His Val Arg Arg Ser His Ser Gly Thr Arg Pro Phe Ala
                 275                 280                 285

 Cys Glu Met Cys Gly Lys Thr Phe Gly His Ala Val Ser Leu Glu
                 290                 295                 300

 Gln His Lys Ala Val His Ser Gln Glu Arg Ser Phe Asp Cys Lys
                 305                 310                 315

 Ile Cys Gly Lys Ser Phe Lys Arg Ser Ser Thr Leu Ser Thr His
                 320                 325                 330

 Leu Leu Ile His Ser Asp Thr Arg Pro Tyr Pro Cys Gln Tyr Cys
                 335                 340                 345

 Gly Lys Arg Phe His Gln Lys Ser Asp Met Lys Lys His Thr Phe
                 350                 355                 360

 Ile His Thr Gly Glu Lys Leu His Lys Cys Gln Val Cys Gly Lys
                 365                 370                 375

 Ala Phe Ser Gln Ser Ser Asn Leu Ile Thr His Ser Arg Lys His
                 380                 385                 390

 Thr Gly Phe Lys Pro Phe Gly Cys Asp Leu Cys Gly Lys Gly Phe
                 395                 400                 405

 Gln Arg Lys Val Asp Leu Arg Arg His Arg Glu Thr Gln His Gly
                 410                 415                 420

 Leu Lys


<210> 6042
<211> 1546
<212> DNA
<213> Homo sapien

<400> 6042
 cgtcgccacc gcagccgccc gagaggagct gggggaggac ggtggcccgc 50

 gaggctcgtc gcagacaacg cggcggcgat gtccgcgagc caggcgagtg 100

 ccgcggcggc agcggcgggg ccttgcgcgc ggcagggcgg cctgggcttc 150

 ggcctccctc cggttccctg gaagcgggcc cgcgaccagc gcgggagcag 200

 cagcagaggc ggaggctcca gcgcgtctct ctcctccccc tcagcctgag 250

 ccgggggaag ccaggcggcc cgggtgtctg gagggggggg gtccgctgcc 300

 cgagaatggg aattctcttc actagaatat ggagactgtt caatcaccag 350

 gagcacaaag ttatcattgt tgggctggat aatgcaggga aaactaccat 400

 tctttaccaa ttttctatga atgaagttgt acatacatct cctacaatag 450

 gaagtaatgt agaagagata gtgattaata atacacgttt cctaatgtgg 500

 gatattggtg gccaagaatc tcttcgttct tcctggaaca cttactatac 550

 taacacagag tttgtaatag ttgttgtgga cagtacagac agagagagga 600

 tttctgtaac tagagaagaa ctctataaaa tgttagcgca tgaggaccta 650

 agaaaagctg gattgctgat ttttgctaat aaacaagatg ttaaagaatg 700

 catgactgta gcagaaatct cccagttttt gaagctaact tctattaaag 750

 atcaccagtg gcatatccag gcatgctgtg ctctaactgg cgagggattg 800

 tgccaaggac ttgaatggat gatgtcacga cttaagatta gatgatctct 850

 actgacctct tctcatagat tttgtataaa tgaagtgctg gactttacct 900

 gaaagctgca aaaattaatg gtttagatat atttataata aactgattta 950

 aactttttct ataagaagaa aaattaagac cacttatttg aaaacaaaga 1000

 tgaagtctca ccttccagtt tgctttctca ttagtttttt ccaaagtaag 1050

 ttattgaagc tgtgattgac atttttctca taatgaatcc tctcaggaca 1100

 ttgtgtagcc tatggtaagt acaaagggag aggaagacat tttgaatttt 1150

 aagagcttta ttatcagttt aaccctccct agttgaatgt tattttcttc 1200

 ttgttccatt aagtcagaat acaaatcagc acagatattc gaatgtttcc 1250

 aatattttaa aatgtaatgt tacttatgaa aagtattttg cttaaggttg 1300

 tgtgtgtatt gtgtatatac ctcaagttca agttaatggc attgatttat 1350

 gttccagaca aaaataacac aaataataat atccttcgtt ataaccacaa 1400

 tgagataagt attggcatta gtgttcagtg ccattttata ctttctctct 1450

 gtgttctctg tattgtacta accaacctcc caaatcgctg agctgcttgt 1500

 ttaaaaaaaa aaaaaaggaa aaggaaaaag caaaaaaaaa aaaaaa 1546

<210> 6043
<211> 179
<212> PRT
<213> Homo sapien

<400> 6043
 Met Gly Ile Leu Phe Thr Arg Ile Trp Arg Leu Phe Asn His Gln
   1               5                  10                  15

 Glu His Lys Val Ile Ile Val Gly Leu Asp Asn Ala Gly Lys Thr
                  20                  25                  30

 Thr Ile Leu Tyr Gln Phe Ser Met Asn Glu Val Val His Thr Ser
                  35                  40                  45

 Pro Thr Ile Gly Ser Asn Val Glu Glu Ile Val Ile Asn Asn Thr
                  50                  55                  60

 Arg Phe Leu Met Trp Asp Ile Gly Gly Gln Glu Ser Leu Arg Ser
                  65                  70                  75

 Ser Trp Asn Thr Tyr Tyr Thr Asn Thr Glu Phe Val Ile Val Val
                  80                  85                  90

 Val Asp Ser Thr Asp Arg Glu Arg Ile Ser Val Thr Arg Glu Glu
                  95                 100                 105

 Leu Tyr Lys Met Leu Ala His Glu Asp Leu Arg Lys Ala Gly Leu
                 110                 115                 120

 Leu Ile Phe Ala Asn Lys Gln Asp Val Lys Glu Cys Met Thr Val
                 125                 130                 135

 Ala Glu Ile Ser Gln Phe Leu Lys Leu Thr Ser Ile Lys Asp His
                 140                 145                 150

 Gln Trp His Ile Gln Ala Cys Cys Ala Leu Thr Gly Glu Gly Leu
                 155                 160                 165

 Cys Gln Gly Leu Glu Trp Met Met Ser Arg Leu Lys Ile Arg
                 170                 175

<210> 6044
<211> 3178
<212> DNA
<213> Homo sapien

<400> 6044
 ggcaccgatt cggggcctgc ccggacttcg ccgcacgctg cagaacctcg 50

 cccagcgccc accatgcccc ggcagctcag cgcggcggcc gcgctcttcg 100

 cgtccctggc cgtaattttg cacgatggca gtcaaatgag agcaaaagca 150

 tttccagaaa ccagagatta ttctcaacct actgcagcag caacagtaca 200

 ggacataaaa aaacctgtcc agcaaccagc taagcaagca cctcaccaaa 250

 ctttagcagc aagattcatg gatggtcata tcacctttca aacagcggcc 300

 acagtaaaaa ttccaacaac taccccagca actacaaaaa acactgcaac 350

 caccagccca attacctaca ccctggtcac aacccaggcc acacccaaca 400

 actcacacac agctcctcca gttactgaag ttacagtcgg ccctagctta 450

 gccccttatt cactgccacc caccatcacc ccaccagctc atacagctgg 500

 aaccagttca tcaaccgtca gccacacaac tgggaacacc actcaaccca 550

 gtaaccagac cacccttcca gcaactttat cgatagcact gcacaaaagc 600

 acaaccggtc agaagcctga tcaacccacc catgccccag gaacaacggc 650

 agctgcccac aataccaccc gcacagctgc acctgcctcc acggttcctg 700

 ggcccaccct tgcacctcag ccatcgtcag tcaagactgg aatttatcag 750

 gttctaaacg gaagcagact ctgtataaaa gcagagatgg ggatacagct 800

 gattgttcaa gacaaggagt cggttttttc acctcggaga tacttcaaca 850

 tcgaccccaa cgcaacgcaa gcctctggga actgtggcac ccgaaaatcc 900

 aaccttctgt tgaattttca gggcggattt gtgaatctca catttaccaa 950

 ggatgaagaa tcatattata tcagtgaagt gggagcctat ttgaccgtct 1000

 cagatccaga gacagtttac caaggaatca aacatgcggt ggtgatgttc 1050

 cagacagcag tcgggcattc cttcaagtgc gtgagtgaac agagcctcca 1100

 gttgtcagcc cacctgcagg tgaaaacaac cgatgtccaa cttcaagcct 1150

 ttgattttga agatgaccac tttggaaatg tggatgagtg ctcgtctgac 1200

 tacacaattg tgcttcctgt gattggggcc atcgtggttg gtctctgcct 1250

 tatgggtatg ggtgtctata aaatccgcct aaggtgtcaa tcatctggat 1300

 accagagaat ctaattgttg cccgggggga atgaaaataa tggaatttag 1350

 agaactcttt catcccttcc aggatggatg ttgggaaatt ccctcagagt 1400

 gtgggtcctt caaacaatgt aaaccaccat cttctattca aatgaagtga 1450

 gtcatgtgtg atttaagttc aggcagcaca tcaatttcta aatacttttt 1500

 gtttatttta tgaaagatat agtgagctgt ttattttcta gtttccttta 1550

 gaatatttta gccactcaaa gtcaacattt gagatatgtt gaattaacat 1600

 aatatatgta aagtagaata agccttcaaa ttataaacca agggtcaatt 1650

 gtaactaata ctactgtgtg tgcattgaag attttatttt acccttgatc 1700

 ttaacaaagc ctttgctttg ttatcaaatg gactttcagt gcttttacta 1750

 tctgtgtttt atggtttcat gtaacataca tattcctggt gtagcactta 1800

 actccttttc cactttaaat ttgtttttgt tttttgagac ggagtttcac 1850

 tcttgtcacc caggctggag tacagtggca cgatctcggc ttatggcaac 1900

 ctccgcctcc cgggttcaag tgattctcct gcttcagctt cccgagtagc 1950

 tgggattaca ggcacacact accacgcctg gctaattttt gtatttttat 2000

 tatagacggg tttcaccatg ttggccagac tggtcttgaa ctcttgacct 2050

 caggtgatcc acccacctca gcctcccaaa gtgctgggat tacaggcatg 2100

 agccattgcg cccggcctta aatgtttttt ttaatcatca aaaagaacaa 2150

 catatctcag gttgtctaag tgtttttatg taaaaccaac aaaaagaaca 2200

 aatcagctta tattttttat cttgatgact cctgctccag aattgctaga 2250

 ctaagaatta ggtggctaca gatggtagaa ctaaacaata agcaagagac 2300

 aataataatg gcccttaatt attaacaaag tgccagagtc taggctaagc 2350

 actttatcta tatctcattt cattctcaca acttataagt gaatgagtaa 2400

 actgagactt aagggaactg aatcacttaa atgtcacctg gctaactgat 2450

 ggcagagcca gagcttgaat tcatgttggt ctgacatcaa ggtctttggt 2500

 cttctcccta caccaagtta cctacaagaa caatgacacc acactctgcc 2550

 tgaaggctca cacctcatac cagcatacgc tcaccttaca gggaaatggg 2600

 tttatccagg atcatgagac attagggtag atgaaaggag agctttgcag 2650

 ataacaaaat agcctatcct taataaatcc tccactctct ggaaggagac 2700

 tgaggggctt tgtaaaacat tagtcagttg ctcattttta tgggattgct 2750

 tagctgggct gtaaagatga aggcatcaaa taaactcaaa gtatttttaa 2800

 atttttttga taatagagaa acttcgctaa ccaactgttc tttcttgagt 2850

 gtatagcccc atcttgtggt aacttgctgc ttctgcactt catatccata 2900

 tttcctattg ttcactttat tctgtagagc agcctgccaa gaattttatt 2950

 tctgctgttt tttttgctgc taaagaaagg aactaagtca ggatgttaac 3000

 agaaaagtcc acataaccct agaattctta gtcaaggaat aattcaagtc 3050

 agcctagaga ccatgttgac tttcctcatg tgtttcctta tgactcagta 3100

 agttggcaag gtcctgactt tagtcttaat aaaacattga attgtagtaa 3150

 aggtttttgc aataaaaact tactttgg 3178

<210> 6045
<211> 416
<212> PRT
<213> Homo sapien

<400> 6045
 Met Pro Arg Gln Leu Ser Ala Ala Ala Ala Leu Phe Ala Ser Leu
   1               5                  10                  15

 Ala Val Ile Leu His Asp Gly Ser Gln Met Arg Ala Lys Ala Phe
                  20                  25                  30

 Pro Glu Thr Arg Asp Tyr Ser Gln Pro Thr Ala Ala Ala Thr Val
                  35                  40                  45

 Gln Asp Ile Lys Lys Pro Val Gln Gln Pro Ala Lys Gln Ala Pro
                  50                  55                  60

 His Gln Thr Leu Ala Ala Arg Phe Met Asp Gly His Ile Thr Phe
                  65                  70                  75

 Gln Thr Ala Ala Thr Val Lys Ile Pro Thr Thr Thr Pro Ala Thr
                  80                  85                  90

 Thr Lys Asn Thr Ala Thr Thr Ser Pro Ile Thr Tyr Thr Leu Val
                  95                 100                 105

 Thr Thr Gln Ala Thr Pro Asn Asn Ser His Thr Ala Pro Pro Val
                 110                 115                 120

 Thr Glu Val Thr Val Gly Pro Ser Leu Ala Pro Tyr Ser Leu Pro
                 125                 130                 135

 Pro Thr Ile Thr Pro Pro Ala His Thr Ala Gly Thr Ser Ser Ser
                 140                 145                 150

 Thr Val Ser His Thr Thr Gly Asn Thr Thr Gln Pro Ser Asn Gln
                 155                 160                 165

 Thr Thr Leu Pro Ala Thr Leu Ser Ile Ala Leu His Lys Ser Thr
                 170                 175                 180

 Thr Gly Gln Lys Pro Asp Gln Pro Thr His Ala Pro Gly Thr Thr
                 185                 190                 195

 Ala Ala Ala His Asn Thr Thr Arg Thr Ala Ala Pro Ala Ser Thr
                 200                 205                 210

 Val Pro Gly Pro Thr Leu Ala Pro Gln Pro Ser Ser Val Lys Thr
                 215                 220                 225

 Gly Ile Tyr Gln Val Leu Asn Gly Ser Arg Leu Cys Ile Lys Ala
                 230                 235                 240

 Glu Met Gly Ile Gln Leu Ile Val Gln Asp Lys Glu Ser Val Phe
                 245                 250                 255

 Ser Pro Arg Arg Tyr Phe Asn Ile Asp Pro Asn Ala Thr Gln Ala
                 260                 265                 270

 Ser Gly Asn Cys Gly Thr Arg Lys Ser Asn Leu Leu Leu Asn Phe
                 275                 280                 285

 Gln Gly Gly Phe Val Asn Leu Thr Phe Thr Lys Asp Glu Glu Ser
                 290                 295                 300

 Tyr Tyr Ile Ser Glu Val Gly Ala Tyr Leu Thr Val Ser Asp Pro
                 305                 310                 315

 Glu Thr Val Tyr Gln Gly Ile Lys His Ala Val Val Met Phe Gln
                 320                 325                 330

 Thr Ala Val Gly His Ser Phe Lys Cys Val Ser Glu Gln Ser Leu
                 335                 340                 345

 Gln Leu Ser Ala His Leu Gln Val Lys Thr Thr Asp Val Gln Leu
                 350                 355                 360

 Gln Ala Phe Asp Phe Glu Asp Asp His Phe Gly Asn Val Asp Glu
                 365                 370                 375

 Cys Ser Ser Asp Tyr Thr Ile Val Leu Pro Val Ile Gly Ala Ile
                 380                 385                 390

 Val Val Gly Leu Cys Leu Met Gly Met Gly Val Tyr Lys Ile Arg
                 395                 400                 405

 Leu Arg Cys Gln Ser Ser Gly Tyr Gln Arg Ile
                 410                 415

<210> 6046
<211> 4485
<212> DNA
<213> Homo sapien

<400> 6046
 gtagacagat ccaggctcac cagtcctgtg ccactgggct tttggcgttc 50

 tgcacaaggc ctacccgcag atgccatgcc tgctccccca gcctaatggg 100

 ctttgatggg ggaagagggt ggttcagcct ctcacgatga ggaggaaaga 150

 gcaagtgtcc tcctcggaca ttctccgggt tgtgaaatgt gctcgcagga 200

 ggcttttcag gcacagagga gccagctggt cgagctgctg gtctcagggt 250

 ccctggaagg cttcgagagt gtcctggact ggctgctgtc ctgggaggtc 300

 ctctcctggg aggactacga gggcttccac ctcctgggcc agcctctctc 350

 ccacttggcc aggcgccttc tggacaccgt ctggaataag ggtacttggg 400

 cctgtcagaa gctcatcgcg gctgcccaag aagcccaggc cgacagccag 450

 tcccccaagc tgcatggctg ctgggacccc cactcgctcc acccagcccg 500

 agacctgcag agtcaccggc cagccattgt caggaggctc cacagccatg 550

 tggagaacat gctggacctg gcatgggagc ggggtttcgt cagccagtat 600

 gaatgtgatg aaatcaggtt gccgatcttc acaccgtccc agagggcaag 650

 aaggctgctt gatcttgcca cggtgaaagc gaatggattg gctgccttcc 700

 ttctacaaca tgttcaggaa ttaccagtcc cattggccct gcctttggaa 750

 gctgccacat gcaagaagta tatggccaag ctgaggacca cggtgtctgc 800

 tcagtctcgc ttcctcagta cctatgatgg agcagagacg ctctgcctgg 850

 aggacatata cacagagaat gtcctggagg tctgggcaga tgtgggcatg 900

 gctggacccc cgcagaagag cccagccacc ctgggcctgg aggagctctt 950

 cagcacccct ggccacctca atgacgatgc ggacactgtg ctggtggtgg 1000

 gtgaggcggg cagtggcaag agcacgctcc tgcagcggct gcacttgctg 1050

 tgggctgcag ggcaagactt ccaggaattt ctctttgtct tcccattcag 1100

 ctgccggcag ctgcagtgca tggccaaacc actctctgtg cggactctac 1150

 tctttgagca ctgctgttgg cctgatgttg gtcaagaaga catcttccag 1200

 ttactccttg accaccctga ccgtgtcctg ttaacctttg atggctttga 1250

 cgagttcaag ttcaggttca cggatcgtga acgccactgc tccccgaccg 1300

 accccacctc tgtccagacc ctgctcttca accttctgca gggcaacctg 1350

 ctgaagaatg cccgcaaggt ggtgaccagc cgtccggccg ctgtgtcggc 1400

 gttcctcagg aagtacatcc gcaccgagtt caacctcaag ggcttctctg 1450

 aacagggcat cgagctgtac ctgaggaagc gccatcatga gcccggggtg 1500

 gcggaccgcc tcatccgcct gctccaagag acctcagccc tgcacggttt 1550

 gtgccacctg cctgtcttct catggatggt gtccaaatgc caccaggaac 1600

 tgttgctgca ggaggggggg tccccaaaga ccactacaga tatgtacctg 1650

 ctgattctgc agcattttct gctgcatgcc acccccccag actcagcttc 1700

 ccaaggtctg ggacccagtc ttcttcgggg ccgcctcccc accctcctgc 1750

 acctgggcag actggctctg tggggcctgg gcatgtgctg ctacgtgttc 1800

 tcagcccagc agctccaggc agcacaggtc agccctgatg acatttctct 1850

 tggcttcctg gtgcgtgcca aaggtgtcgt gccagggagt acggcgcccc 1900

 tggaattcct tcacatcact ttccagtgct tctttgccgc gttctacctg 1950

 gcactcagtg ctgatgtgcc accagctttg ctcagacacc tcttcaattg 2000

 tggcaggcca ggcaactcac caatggccag gctcctgccc acgatgtgca 2050

 tccaggcctc ggagggaaag gacagcagcg tggcagcttt gctgcagaag 2100

 gccgagccgc acaaccttca gatcacagca gccttcctgg cagggctgtt 2150

 gtcccgggag cactggggcc tgctggctga gtgccagaca tctgagaagg 2200

 ccctgctccg gcgccaggcc tgtgcccgct ggtgtctggc ccgcagcctc 2250

 cgcaagcact tccactccat cccgccagct gcaccgggtg aggccaagag 2300

 cgtgcatgcc atgcccgggt tcatctggct catccggagc ctgtacgaga 2350

 tgcaggagga gcggctggct cggaaggctg cacgtggcct gaatgttggg 2400

 cacctcaagt tgacattttg cagtgtgggc cccactgagt gtgctgccct 2450

 ggcctttgtg ctgcagcacc tccggcggcc cgtggccctg cagctggact 2500

 acaactctgt gggtgacatt ggcgtggagc agctgctgcc ttgccttggt 2550

 gtctgcaagg ctctgtattt gcgcgataac aatatctcag accgaggcat 2600

 ctgcaagctc attgaatgtg ctcttcactg cgagcaattg cagaagttag 2650

 ctctattcaa caacaaattg actgacggct gtgcacactc catggctaag 2700

 ctccttgcat gcaggcagaa cttcttggca ttgaggctgg ggaataacta 2750

 catcactgcc gcgggagccc aagtgctggc cgaggggctc cgaggcaaca 2800

 cctccttgca gttcctggga ttctggggca acagagtggg tgacgagggg 2850

 gcccaggccc tggctgaagc cttgggtgat caccagagct tgaggtggct 2900

 cagcctggtg gggaacaaca ttggcagtgt gggtgcccaa gccttggcac 2950

 tgatgctggc aaagaacgtc atgctagaag aactctgcct ggaggagaac 3000

 catctccagg atgaaggtgt atgttctctc gcagaaggac tgaagaaaaa 3050

 ttcaagtttg aaaatcctga agttgtccaa taactgcatc acctacctag 3100

 gggcagaagc cctcctgcag gcccttgaaa ggaatgacac catcctggaa 3150

 gtctggctcc gagggaacac tttctctcta gaggaggttg acaagctcgg 3200

 ctgcagggac accagactct tgctttgaag tctccgggag gatgttcgtc 3250

 tcagtttgtt tgtgagcagg ctgtgagttt gggccccaga ggctgggtga 3300

 catgtgttgg cagcctcttc aaaatgagcc ctgtcctgcc taaggctgaa 3350

 cttgttttct gggaacacca taggtcacct ttattctggc agaggaggga 3400

 gcatcagtgc cctccaggat agacttttcc caagcctact tttgccattg 3450

 acttcttccc aagattcaat cccaggatgt acaaggacag cccctcctcc 3500

 atagtatggg actggcctct gctgatcctc ccaggcttcc gtgtgggtca 3550

 gtggggccca tggatgtgct tgttaactga gtgccttttg gtggagaggc 3600

 ccggcctctc acaaaagacc ccttaccact gctctgatga agaggagtac 3650

 acagaacaca taattcagga agcagctttc cccatgtctc gactcatcca 3700

 tccaggccat tccccgtctc tggttcctcc cctcctcctg gactcctgca 3750

 cacgctcctt cctctgaggc tgaaattcag aatattagtg acctcagctt 3800

 tgatatttca cttacagcac ccccaaccct ggcacccagg gtgggaaggg 3850

 ctacacctta gcctgccctc ctttccggtg tttaagacat ttttggaagg 3900

 ggacacgtga cagccgtttg ttccccaaga cattctaggt ttgcaagaaa 3950

 aatatgacca cactccagct gggatcacat gtggactttt atttccagtg 4000

 aaatcagtta ctcttcagtt aagcctttgg aaacagctcg actttaaaaa 4050

 gctccaaatg cagctttaaa aaattaatct gggccagaat ttcaaacggc 4100

 ctcactaggc ttctggttga tgcctgtgaa ctgaactctg acaacagact 4150

 tctgaaatag acccacaaga ggcagttcca tttcatttgt gccagaatgc 4200

 tttaggatgt acagttatgg attgaaagtt tacaggaaaa aaaattaggc 4250

 cgttccttca aagcaaatgt cttcctggat tattcaaaat gatgtatgtt 4300

 gaagcctttg taaattgtca gatgctgtgc aaatgttatt attttaaaca 4350

 ttatgatgtg tgaaaactgg ttaatattta taggtcactt tgttttactg 4400

 tcttaagttt atactcttat agacaacatg gccgtgaact ttatgctgta 4450

 aataatcaga ggggaataaa ctgttgagtc aaaac 4485

<210> 6047
<211> 1040
<212> PRT
<213> Homo sapien

<400> 6047
 Met Gly Glu Glu Gly Gly Ser Ala Ser His Asp Glu Glu Glu Arg
   1               5                  10                  15

 Ala Ser Val Leu Leu Gly His Ser Pro Gly Cys Glu Met Cys Ser
                  20                  25                  30

 Gln Glu Ala Phe Gln Ala Gln Arg Ser Gln Leu Val Glu Leu Leu
                  35                  40                  45

 Val Ser Gly Ser Leu Glu Gly Phe Glu Ser Val Leu Asp Trp Leu
                  50                  55                  60

 Leu Ser Trp Glu Val Leu Ser Trp Glu Asp Tyr Glu Gly Phe His
                  65                  70                  75

 Leu Leu Gly Gln Pro Leu Ser His Leu Ala Arg Arg Leu Leu Asp
                  80                  85                  90

 Thr Val Trp Asn Lys Gly Thr Trp Ala Cys Gln Lys Leu Ile Ala
                  95                 100                 105

 Ala Ala Gln Glu Ala Gln Ala Asp Ser Gln Ser Pro Lys Leu His
                 110                 115                 120

 Gly Cys Trp Asp Pro His Ser Leu His Pro Ala Arg Asp Leu Gln
                 125                 130                 135

 Ser His Arg Pro Ala Ile Val Arg Arg Leu His Ser His Val Glu
                 140                 145                 150

 Asn Met Leu Asp Leu Ala Trp Glu Arg Gly Phe Val Ser Gln Tyr
                 155                 160                 165

 Glu Cys Asp Glu Ile Arg Leu Pro Ile Phe Thr Pro Ser Gln Arg
                 170                 175                 180

 Ala Arg Arg Leu Leu Asp Leu Ala Thr Val Lys Ala Asn Gly Leu
                 185                 190                 195

 Ala Ala Phe Leu Leu Gln His Val Gln Glu Leu Pro Val Pro Leu
                 200                 205                 210

 Ala Leu Pro Leu Glu Ala Ala Thr Cys Lys Lys Tyr Met Ala Lys
                 215                 220                 225

 Leu Arg Thr Thr Val Ser Ala Gln Ser Arg Phe Leu Ser Thr Tyr
                 230                 235                 240

 Asp Gly Ala Glu Thr Leu Cys Leu Glu Asp Ile Tyr Thr Glu Asn
                 245                 250                 255

 Val Leu Glu Val Trp Ala Asp Val Gly Met Ala Gly Pro Pro Gln
                 260                 265                 270

 Lys Ser Pro Ala Thr Leu Gly Leu Glu Glu Leu Phe Ser Thr Pro
                 275                 280                 285

 Gly His Leu Asn Asp Asp Ala Asp Thr Val Leu Val Val Gly Glu
                 290                 295                 300

 Ala Gly Ser Gly Lys Ser Thr Leu Leu Gln Arg Leu His Leu Leu
                 305                 310                 315

 Trp Ala Ala Gly Gln Asp Phe Gln Glu Phe Leu Phe Val Phe Pro
                 320                 325                 330

 Phe Ser Cys Arg Gln Leu Gln Cys Met Ala Lys Pro Leu Ser Val
                 335                 340                 345

 Arg Thr Leu Leu Phe Glu His Cys Cys Trp Pro Asp Val Gly Gln
                 350                 355                 360

 Glu Asp Ile Phe Gln Leu Leu Leu Asp His Pro Asp Arg Val Leu
                 365                 370                 375

 Leu Thr Phe Asp Gly Phe Asp Glu Phe Lys Phe Arg Phe Thr Asp
                 380                 385                 390

 Arg Glu Arg His Cys Ser Pro Thr Asp Pro Thr Ser Val Gln Thr
                 395                 400                 405

 Leu Leu Phe Asn Leu Leu Gln Gly Asn Leu Leu Lys Asn Ala Arg
                 410                 415                 420

 Lys Val Val Thr Ser Arg Pro Ala Ala Val Ser Ala Phe Leu Arg
                 425                 430                 435

 Lys Tyr Ile Arg Thr Glu Phe Asn Leu Lys Gly Phe Ser Glu Gln
                 440                 445                 450

 Gly Ile Glu Leu Tyr Leu Arg Lys Arg His His Glu Pro Gly Val
                 455                 460                 465

 Ala Asp Arg Leu Ile Arg Leu Leu Gln Glu Thr Ser Ala Leu His
                 470                 475                 480

 Gly Leu Cys His Leu Pro Val Phe Ser Trp Met Val Ser Lys Cys
                 485                 490                 495

 His Gln Glu Leu Leu Leu Gln Glu Gly Gly Ser Pro Lys Thr Thr
                 500                 505                 510

 Thr Asp Met Tyr Leu Leu Ile Leu Gln His Phe Leu Leu His Ala
                 515                 520                 525

 Thr Pro Pro Asp Ser Ala Ser Gln Gly Leu Gly Pro Ser Leu Leu
                 530                 535                 540

 Arg Gly Arg Leu Pro Thr Leu Leu His Leu Gly Arg Leu Ala Leu
                 545                 550                 555

 Trp Gly Leu Gly Met Cys Cys Tyr Val Phe Ser Ala Gln Gln Leu
                 560                 565                 570

 Gln Ala Ala Gln Val Ser Pro Asp Asp Ile Ser Leu Gly Phe Leu
                 575                 580                 585

 Val Arg Ala Lys Gly Val Val Pro Gly Ser Thr Ala Pro Leu Glu
                 590                 595                 600

 Phe Leu His Ile Thr Phe Gln Cys Phe Phe Ala Ala Phe Tyr Leu
                 605                 610                 615

 Ala Leu Ser Ala Asp Val Pro Pro Ala Leu Leu Arg His Leu Phe
                 620                 625                 630

 Asn Cys Gly Arg Pro Gly Asn Ser Pro Met Ala Arg Leu Leu Pro
                 635                 640                 645

 Thr Met Cys Ile Gln Ala Ser Glu Gly Lys Asp Ser Ser Val Ala
                 650                 655                 660

 Ala Leu Leu Gln Lys Ala Glu Pro His Asn Leu Gln Ile Thr Ala
                 665                 670                 675

 Ala Phe Leu Ala Gly Leu Leu Ser Arg Glu His Trp Gly Leu Leu
                 680                 685                 690

 Ala Glu Cys Gln Thr Ser Glu Lys Ala Leu Leu Arg Arg Gln Ala
                 695                 700                 705

 Cys Ala Arg Trp Cys Leu Ala Arg Ser Leu Arg Lys His Phe His
                 710                 715                 720

 Ser Ile Pro Pro Ala Ala Pro Gly Glu Ala Lys Ser Val His Ala
                 725                 730                 735

 Met Pro Gly Phe Ile Trp Leu Ile Arg Ser Leu Tyr Glu Met Gln
                 740                 745                 750

 Glu Glu Arg Leu Ala Arg Lys Ala Ala Arg Gly Leu Asn Val Gly
                 755                 760                 765

 His Leu Lys Leu Thr Phe Cys Ser Val Gly Pro Thr Glu Cys Ala
                 770                 775                 780

 Ala Leu Ala Phe Val Leu Gln His Leu Arg Arg Pro Val Ala Leu
                 785                 790                 795

 Gln Leu Asp Tyr Asn Ser Val Gly Asp Ile Gly Val Glu Gln Leu
                 800                 805                 810

 Leu Pro Cys Leu Gly Val Cys Lys Ala Leu Tyr Leu Arg Asp Asn
                 815                 820                 825

 Asn Ile Ser Asp Arg Gly Ile Cys Lys Leu Ile Glu Cys Ala Leu
                 830                 835                 840

 His Cys Glu Gln Leu Gln Lys Leu Ala Leu Phe Asn Asn Lys Leu
                 845                 850                 855

 Thr Asp Gly Cys Ala His Ser Met Ala Lys Leu Leu Ala Cys Arg
                 860                 865                 870

 Gln Asn Phe Leu Ala Leu Arg Leu Gly Asn Asn Tyr Ile Thr Ala
                 875                 880                 885

 Ala Gly Ala Gln Val Leu Ala Glu Gly Leu Arg Gly Asn Thr Ser
                 890                 895                 900

 Leu Gln Phe Leu Gly Phe Trp Gly Asn Arg Val Gly Asp Glu Gly
                 905                 910                 915

 Ala Gln Ala Leu Ala Glu Ala Leu Gly Asp His Gln Ser Leu Arg
                 920                 925                 930

 Trp Leu Ser Leu Val Gly Asn Asn Ile Gly Ser Val Gly Ala Gln
                 935                 940                 945

 Ala Leu Ala Leu Met Leu Ala Lys Asn Val Met Leu Glu Glu Leu
                 950                 955                 960

 Cys Leu Glu Glu Asn His Leu Gln Asp Glu Gly Val Cys Ser Leu
                 965                 970                 975

 Ala Glu Gly Leu Lys Lys Asn Ser Ser Leu Lys Ile Leu Lys Leu
                 980                 985                 990

 Ser Asn Asn Cys Ile Thr Tyr Leu Gly Ala Glu Ala Leu Leu Gln
                 995                1000                1005

 Ala Leu Glu Arg Asn Asp Thr Ile Leu Glu Val Trp Leu Arg Gly
                1010                1015                1020

 Asn Thr Phe Ser Leu Glu Glu Val Asp Lys Leu Gly Cys Arg Asp
                1025                1030                1035

 Thr Arg Leu Leu Leu
                1040

<210> 6048
<211> 2420
<212> DNA
<213> Homo sapien

<400> 6048
 aaaaatgtgt gtttgtgggt gaaatggctg cgcaggtcgg agcggtgcgc 50

 gtagtacggg cggtggcggc gcaggaggag ccggacaaag aggggaagga 100

 gaaacctcat gctggggtct ccccgcgggg agttaaacgg cagcgccgat 150

 ctagcagtgg ggggtctcag gagaagcggg ggcggccgag ccaggagccc 200

 cctctcgctc cccctcaccg gcggcgtcgc agccgccgac atcctgggcc 250

 gctgccgccg acgaatgcag ccccaactgt cccaggccct gttgagcctc 300

 ttctcctgcc gcctccgccg ccaccttcgc tggcacccgc cgggcccgct 350

 gtcgctgccc ctctcccggc cccaagcacc tcggccctct tcaccttctc 400

 gcctctgacg gtgagcgcgg ccgggcccaa gcataagggc cacaaggagc 450

 ggcacaagca ccatcaccac cgcggccccg atggtgatcc cagctcctgc 500

 ggaaccgatc tcaagcacaa ggacaagcag gaaaacggcg agaggactgg 550

 aggggtgcct ctgatcaaag cccccaagag agaaacacca gatgaaaatg 600

 gtaaaaccca gagagccgat gattttgtct tgaagaaaat aaagaagaaa 650

 aagaaaaaga aacaccgaga agacatgcga ggaagacgcc ttaaaatgta 700

 caataaggaa gtacaaaccg tctgtgctgg cctgacccgc atcagtaaag 750

 aaattctcac ccaaggacaa ataaatagca cttcaggact taataaggag 800

 tccttcaggt atctgaaaga tgaacagctg tgccgattaa atttgggtat 850

 gcaagaatat cgggtacccc agggagtaca aacacctttt atgactcacc 900

 aggaacattc tattcgtaga aatttcttaa aaacaggtac taaatttagc 950

 aactttattc atgaggaaca ccagtccaat ggtggtgctc ttgtccttca 1000

 tgcttacatg gatgaactct catttttgtc tccaatggag atggagagat 1050

 tttctgagga gtttcttgct ttgacattca gtgaaaatga gaaaaatgct 1100

 gcttactatg ctttagcaat agtgcatgga gcggctgctt atctcccaga 1150

 cttcttggac tactttgctt ttaatttccc caacactcca gtgaaaatgg 1200

 aaattctggg caagaaagat attgaaacaa ccaccatttc aaattttcac 1250

 actcaggtca acaggacata ctgctgtggc acctaccgag caggtcctat 1300

 gcggcagata agtctcgttg gagcagtaga tgaagaagtt ggtgattatt 1350

 tcccagagtt ccttgatatg ttagaagaat caccatttct gaaaatgact 1400

 ttgccctggg gtacactttc tagcctccga ctccagtgta ggtcccagag 1450

 tgatgatggg cctataatgt gggtaaggcc aggagaacag atgatcccta 1500

 cagcagatat gccaaagtca cccttcaaaa gacgacgatc aatgaatgaa 1550

 ataaaaaatc tccagtacct acctcggacc agtgaacccc gcgaagttct 1600

 ctttgaagat aggactagag ctcatgctga tcatgtcggt caggggtttg 1650

 actggcagag tacggctgct gttggagttt tgaaagctgt acaatttggt 1700

 gaatggagtg accaacctcg cataaccaaa gatgtgattt gttttcatgc 1750

 tgaggatttt actgatgttg tacaaagact tcagttagat cttcatgaac 1800

 ctccagtttc ccagtgcgta cagtgggtag atgaagctaa actaaaccaa 1850

 atgaggcggg aaggcattcg ttatgctaga attcagcttt gcgacaatga 1900

 tatctacttc atccctagaa atgtcattca tcagttcaaa acagtttcgg 1950

 cggtgtgcag cttagcctgg catataaggc ttaaacagta ccaccctgtt 2000

 gtggaagcca ctcaaaacac agaaagcaat tctaacatgg actgtggttt 2050

 aactggaaag cgagaattag aagttgactc ccaatgtgtg aggataaaaa 2100

 ctgaatctga agaagcatgc acagagattc agctgttaac aactgcctca 2150

 tcatctttcc cacctgcatc agaacttaat ctacagcaag atcagaagac 2200

 tcagcctatt ccagttttaa aagtggaaag tagactggac tctgaccagc 2250

 aacacaatct gcaagaacat tcaaccactt ctgtgtgata tgtacatatt 2300

 caaacacatt ttttaacttt tttaaatttt gatgtgaagt tatagtttta 2350

 taactggctt aagttaagtt ttattggaga aatcttgcct ataattctat 2400

 aaagagaaat gacattccac 2420

<210> 6049
<211> 754
<212> PRT
<213> Homo sapien

<400> 6049
 Met Ala Ala Gln Val Gly Ala Val Arg Val Val Arg Ala Val Ala
   1               5                  10                  15

 Ala Gln Glu Glu Pro Asp Lys Glu Gly Lys Glu Lys Pro His Ala
                  20                  25                  30

 Gly Val Ser Pro Arg Gly Val Lys Arg Gln Arg Arg Ser Ser Ser
                  35                  40                  45

 Gly Gly Ser Gln Glu Lys Arg Gly Arg Pro Ser Gln Glu Pro Pro
                  50                  55                  60

 Leu Ala Pro Pro His Arg Arg Arg Arg Ser Arg Arg His Pro Gly
                  65                  70                  75

 Pro Leu Pro Pro Thr Asn Ala Ala Pro Thr Val Pro Gly Pro Val
                  80                  85                  90

 Glu Pro Leu Leu Leu Pro Pro Pro Pro Pro Pro Ser Leu Ala Pro
                  95                 100                 105

 Ala Gly Pro Ala Val Ala Ala Pro Leu Pro Ala Pro Ser Thr Ser
                 110                 115                 120

 Ala Leu Phe Thr Phe Ser Pro Leu Thr Val Ser Ala Ala Gly Pro
                 125                 130                 135

 Lys His Lys Gly His Lys Glu Arg His Lys His His His His Arg
                 140                 145                 150

 Gly Pro Asp Gly Asp Pro Ser Ser Cys Gly Thr Asp Leu Lys His
                 155                 160                 165

 Lys Asp Lys Gln Glu Asn Gly Glu Arg Thr Gly Gly Val Pro Leu
                 170                 175                 180

 Ile Lys Ala Pro Lys Arg Glu Thr Pro Asp Glu Asn Gly Lys Thr
                 185                 190                 195

 Gln Arg Ala Asp Asp Phe Val Leu Lys Lys Ile Lys Lys Lys Lys
                 200                 205                 210

 Lys Lys Lys His Arg Glu Asp Met Arg Gly Arg Arg Leu Lys Met
                 215                 220                 225

 Tyr Asn Lys Glu Val Gln Thr Val Cys Ala Gly Leu Thr Arg Ile
                 230                 235                 240

 Ser Lys Glu Ile Leu Thr Gln Gly Gln Ile Asn Ser Thr Ser Gly
                 245                 250                 255

 Leu Asn Lys Glu Ser Phe Arg Tyr Leu Lys Asp Glu Gln Leu Cys
                 260                 265                 270

 Arg Leu Asn Leu Gly Met Gln Glu Tyr Arg Val Pro Gln Gly Val
                 275                 280                 285

 Gln Thr Pro Phe Met Thr His Gln Glu His Ser Ile Arg Arg Asn
                 290                 295                 300

 Phe Leu Lys Thr Gly Thr Lys Phe Ser Asn Phe Ile His Glu Glu
                 305                 310                 315

 His Gln Ser Asn Gly Gly Ala Leu Val Leu His Ala Tyr Met Asp
                 320                 325                 330

 Glu Leu Ser Phe Leu Ser Pro Met Glu Met Glu Arg Phe Ser Glu
                 335                 340                 345

 Glu Phe Leu Ala Leu Thr Phe Ser Glu Asn Glu Lys Asn Ala Ala
                 350                 355                 360

 Tyr Tyr Ala Leu Ala Ile Val His Gly Ala Ala Ala Tyr Leu Pro
                 365                 370                 375

 Asp Phe Leu Asp Tyr Phe Ala Phe Asn Phe Pro Asn Thr Pro Val
                 380                 385                 390

 Lys Met Glu Ile Leu Gly Lys Lys Asp Ile Glu Thr Thr Thr Ile
                 395                 400                 405

 Ser Asn Phe His Thr Gln Val Asn Arg Thr Tyr Cys Cys Gly Thr
                 410                 415                 420

 Tyr Arg Ala Gly Pro Met Arg Gln Ile Ser Leu Val Gly Ala Val
                 425                 430                 435

 Asp Glu Glu Val Gly Asp Tyr Phe Pro Glu Phe Leu Asp Met Leu
                 440                 445                 450

 Glu Glu Ser Pro Phe Leu Lys Met Thr Leu Pro Trp Gly Thr Leu
                 455                 460                 465

 Ser Ser Leu Arg Leu Gln Cys Arg Ser Gln Ser Asp Asp Gly Pro
                 470                 475                 480

 Ile Met Trp Val Arg Pro Gly Glu Gln Met Ile Pro Thr Ala Asp
                 485                 490                 495

 Met Pro Lys Ser Pro Phe Lys Arg Arg Arg Ser Met Asn Glu Ile
                 500                 505                 510

 Lys Asn Leu Gln Tyr Leu Pro Arg Thr Ser Glu Pro Arg Glu Val
                 515                 520                 525

 Leu Phe Glu Asp Arg Thr Arg Ala His Ala Asp His Val Gly Gln
                 530                 535                 540

 Gly Phe Asp Trp Gln Ser Thr Ala Ala Val Gly Val Leu Lys Ala
                 545                 550                 555

 Val Gln Phe Gly Glu Trp Ser Asp Gln Pro Arg Ile Thr Lys Asp
                 560                 565                 570

 Val Ile Cys Phe His Ala Glu Asp Phe Thr Asp Val Val Gln Arg
                 575                 580                 585

 Leu Gln Leu Asp Leu His Glu Pro Pro Val Ser Gln Cys Val Gln
                 590                 595                 600

 Trp Val Asp Glu Ala Lys Leu Asn Gln Met Arg Arg Glu Gly Ile
                 605                 610                 615

 Arg Tyr Ala Arg Ile Gln Leu Cys Asp Asn Asp Ile Tyr Phe Ile
                 620                 625                 630

 Pro Arg Asn Val Ile His Gln Phe Lys Thr Val Ser Ala Val Cys
                 635                 640                 645

 Ser Leu Ala Trp His Ile Arg Leu Lys Gln Tyr His Pro Val Val
                 650                 655                 660

 Glu Ala Thr Gln Asn Thr Glu Ser Asn Ser Asn Met Asp Cys Gly
                 665                 670                 675

 Leu Thr Gly Lys Arg Glu Leu Glu Val Asp Ser Gln Cys Val Arg
                 680                 685                 690

 Ile Lys Thr Glu Ser Glu Glu Ala Cys Thr Glu Ile Gln Leu Leu
                 695                 700                 705

 Thr Thr Ala Ser Ser Ser Phe Pro Pro Ala Ser Glu Leu Asn Leu
                 710                 715                 720

 Gln Gln Asp Gln Lys Thr Gln Pro Ile Pro Val Leu Lys Val Glu
                 725                 730                 735

 Ser Arg Leu Asp Ser Asp Gln Gln His Asn Leu Gln Glu His Ser
                 740                 745                 750

 Thr Thr Ser Val


<210> 6050
<211> 5634
<212> DNA
<213> Homo sapien

<400> 6050
 gccttttccc tccggctcgg gagcgtctcg cttgcgcccc gggcccgcgg 50

 cgcccgcgcg gctgcgagcc tcgggtggcc gcgtgccggc tccaggaagc 100

 cggagagggc gcggcggcca ggatggcgcg gcacgggccg tgcggctaga 150

 cgggagccga gggaaccgcc ggctcgcgcc ctccgttctt tcccggagcc 200

 ggcttcacgc agggccggga acggccgtgc ctctgggatc cgccttcgct 250

 gacgccgggc acctacctgg acgcgagcga gcgagatgcc caaccccaaa 300

 aacagcaaag gcggccgcaa aaacaagcgc gccaacagca gcggcgacga 350

 gcaggaaaat ggagccgggg ccctggcagc ggcgggcgcg gcgggagcgg 400

 cggccggggg ggccctggcg gcggcggccg gttgcggggc ggcggcggcg 450

 ggcgcgccgg gcgccggagg cgcggcgggc gccggaggcg cggggactgg 500

 cgccgcgaac gctgcggccg ccgcgggggc tgcggccgcg ggcgatgcca 550

 aaaacgaagc cccatgtgcc actcccctga tctgcagctt cggtaggccg 600

 gtggacctgg agaaggacga ctaccagaag gtggtgtgca acaacgagca 650

 ctgcccctgc agcacctgga tgcacctgca gtgcttctac gagtgggaga 700

 gcagcatcct cgtccagttc aactgcatcg gccgcgcgcg cagctggaac 750

 gagaagcaat gccgccagaa catgtggaca aagaagggct acgacctggc 800

 cttccgcttc tgctcttgcc gctgtggcca gggccacttg aagaaggaca 850

 cagactggta tcaggtgaag cggatgcagg acgagaaaaa gaagaagtct 900

 ggctccgaga agaacacagg gaggcctcct ggtgaggcgg cggaggaggc 950

 aaaaaagtgc aggcccccaa ataagcccca gaaaggccca agccacgacc 1000

 tcccccgccg gcattccatg gaccggcaga actcccagga gaaggcagtg 1050

 ggtgccgcag cctacggtgc ccgttccccc ggtggctccc cgggccagtc 1100

 cccacccacg ggctactcca tcctctctcc tgcccacttc agcggccccc 1150

 gctcctccag atacctcggg gagttcttaa agaacgccat ccatctggag 1200

 cctcacaaga aggccatggc tgggggccat gtgttcagaa atgcccactt 1250

 tgattacagc cctgcggggt tggcagttca caggggggga cacttcgaca 1300

 cccccgtgca gttccttcgg cggctggacc tctccgaact cctcactcac 1350

 atccccaggc ataagctgaa cactttccac gtgcgcatgg aagacgatgc 1400

 ccaagtgggc cagggggaag acttgcggaa gttcattctg gccgcgctca 1450

 gtgccagcca cagaaacgtg gtaaactgtg ccctgtgcca ccgggcgctc 1500

 ccggtgttcg aacagttccc actggtggat ggaactttgt tcctaagccc 1550

 gtcgagacat gatgagatcg aatatgatgt tccttgtcac cttcaaggga 1600

 gactcatgca tctgtatgcc gtgtgcgtgg actgcctgga aggggttcac 1650

 aagatcatct gcatcaagtg taagtcacgg tgggatggca gctggcacca 1700

 gctgggcact atgtacacct acgacatcct ggctgcctct ccatgttgtc 1750

 aggcccgcct gaactgtaag cactgtggga agccggtgat cgacgtgagg 1800

 atcgggatgc agtacttctc cgaatatagc aacgtccagc agtgtccaca 1850

 ctgtgggaac ctggactacc acttcgtgaa gccattttcc tccttcaaag 1900

 ttctcgaagc ttattgatga aagctttgct ttagtaatag ctattttatt 1950

 gatattatta ctttattaca tatcttttat agggaaacat tctgtgacat 2000

 taatttcctt tctaatttaa aggagagtta ctttgttgta tgtgtgccac 2050

 taaaataggg gctgcccttg ccctgtcttg attcccgagt gttaatctgt 2100

 ggttttgacc agagcccaga tgggtaatcc tgtgcatttg ggttggggtt 2150

 cactcttacc aagaatcttt gatgcagctt taagatggtg gggaggatgg 2200

 ggtgaattta ggaaaggaat ttgtggttat aaactaagag cttgatagga 2250

 gttggaagga aactcttact aaaatgttaa ctttctaaaa accttctttt 2300

 agatcttcct tgggcctttg gaaaaatatg tgacaagtga atgtaagtct 2350

 gtgcctggag agctaatagt gcattagtct atctcagcct agtgttctgc 2400

 agcacacatg ggcaggcagt ttactcacac tgacaggtga cctgaaagtg 2450

 gcacaagtgc tgtttctatc actattgtaa tttgccagtt catttttcat 2500

 gctgaaagta atatccaaat tgtaagacat atgaaagata ttagtgttgc 2550

 aaatatgttt aggtaaactg acctataaca gaatatgtga aatgaatttg 2600

 gaaataatgc aagaaggcag aactcaatca tttaaattgt gtctttgaag 2650

 ttggtaatat agcttttaag gagaacccat gaataacctg atttgggcag 2700

 tgatgattta ttacaggttg cactgttgaa gtgtcatttg gtgtcaggtt 2750

 cttctcacag gtaaatcttt cagccacaga atctaactgg tgagcttcag 2800

 aaccaataat tgccacattt attgtcctca aaattgctta tggccatgtt 2850

 taaccaatta attctgagtt tccaaaatca aagatttgac cttaagaggg 2900

 aagggaaaaa agtgtgaaag gatgatgaag aaaataattt tactatttct 2950

 tttaaaagta tgttttggaa aatcaatgat tttaatgcat agcagtatgt 3000

 ttgaaaaata gaccattcta aaaagcccat gataccttac tgttgatgaa 3050

 aaaggatgat catatatata gaacttgatt agtcagagca ttgggcattc 3100

 caaaatacag cctttggttc agtagatttt aatgctttaa atagactgac 3150

 gtcgcatacc cttatagaat tggaatatga tttctcaaaa attaatttga 3200

 taatttcatg tatgatgtgc atatatgcta aaagaatgca gaaaatcatt 3250

 ttatgaatag ccaaatttgg ggttgatgtg aacattttat gttactcatt 3300

 tggtttatac tttttttttt ttttttttaa ctgtgtggtt tttcttttca 3350

 gaagtattta ggcaatattg cacgtgagtt tcagttcttt ttttcttttt 3400

 tttgagatgg agtctcactc ttgtcaccca ggctggagtg cagtagtgcg 3450

 atctcagctc actgcaacct ctgcctcctg gattcaagcg attctcctgt 3500

 cccagcctcc caggtagctg ggactatagg cacgtgccac cacacccggc 3550

 taattttttg tatttttagt agagacagcg tttcaccatg ttagctagga 3600

 tggtctagat ctcctgacct tgtgatctgc ctgcctcggc ctcccaaagt 3650

 gctgggatta caggcgtgag tcactgcgcc tggccaagtt tcagttctat 3700

 atgaagtatt tgatgttttg tttgaaacaa tacagcatta aagaaccaat 3750

 gttattcact aatatcattc atctttcagt ttggatgatt tggtttgctg 3800

 catctaggtc ggtgtttgat catctgaaaa aacatttcag tgggaagaaa 3850

 tgcataaaat gcctataaga agtagaaagt cattgaactg acagtgtttg 3900

 atgcaactaa aagaggattg taagcatagc tttctgcaaa cttgtcttta 3950

 atgcacaaag ctgtagtggt gaattaacta tctccttatt gattctctcc 4000

 tgtacccaga tgcaaaaagt gctaagtttc tcttgtcctc gtaataccat 4050

 ttggatttta tttctgaatt taaatagtaa aatatttatg atgctgatct 4100

 ttaacccacc taaaatttta tagtgaaacc tgctttatat tgttgttctg 4150

 aagcttacaa ttgacctata cattgcattc agcaagctcc tgaatttaga 4200

 actgccgtca gtgtagtgta tgctgtgttc catgttgcct ttttagatgg 4250

 ctttctaccc cctgaacaat aaataggatg aggttttact gtaattgggt 4300

 aaagtttact cttggacatt atttcgatgc taaagtaagg attctgtgga 4350

 tgttacttaa agagaaaagc ataagagcat gaagcatatc tgggaatatc 4400

 ttttgccttt aagacgattc attcttgtct agagggaaaa tctggctgat 4450

 ttgggaataa aatataatcg aatattcaac accatgaaga taaatcttat 4500

 tttggaaatc tactgacctt aataccccaa gcttgccctg aatactttga 4550

 ttggaattgg aatatatcaa aaaaggttag tatttttgtt gtagttagga 4600

 tactaaaagg atattagtta cccaagagat ccaatttgtt tttctgatga 4650

 atagtgttca gtaaaatgaa gcagtcttaa gagtgactaa taatttcaaa 4700

 gtgatttttc gtctattctt aatatttttt aattatttat ttttaagagt 4750

 tttatacctt gagcagatac aatgatctgc tttagtgaga ggacaatttc 4800

 tgattgattg ttttctcttc aggccatctc acctcttcat tctcttgtta 4850

 catttgaagc agttgatata atgggtttat actttaaaag atagacatgg 4900

 tgccatgaag ttggggagtt gggtgaatta tcccattcta gttacagagg 4950

 agctttcctt aaatgccctt taacttctag gttttgttca agaagttcat 5000

 tttctgagta aaagttattt tcatatatgt tgggggaaaa ttaactcatc 5050

 taaaaagaat cttattaggt atttgaactc taaaactaac agataagaca 5100

 gatatgtacc ttattagagc accagaacta atttgctaag tcttttgttt 5150

 agtcctgcaa gactgatgct taatacacag tctgttctcc tgtgtctagg 5200

 tcaggaactc cagtttgctt ttctgttttg tgtcctggta gcagctgttg 5250

 agtaactttc attggaggtt gggaaggaag tgaggagaaa gtgttcttgt 5300

 ttagtgtttt atttcctata ataggatgct gcctaaccca gttcatctct 5350

 atgtcctgtt cactgaatat tccgggtaat tgaaagaaaa tataatggat 5400

 gggctccatt aaaaccagct caaaaataaa ttcttgtcag taaagatttc 5450

 ttgtcaagat gtcttggatt gcacttttgt tgaggaaaga cagtgtaaat 5500

 agttaaagaa tgttgataaa attgaaacat ttggttgtgg aattgtgtgt 5550

 ggttttagag ggtttctgtt tgtgaaatgt atgtattaaa aataataaaa 5600

 ttccagaaac taaaaaaaaa aaaaaaaaaa aaaa 5634

<210> 6051
<211> 543
<212> PRT
<213> Homo sapien

<400> 6051
 Met Pro Asn Pro Lys Asn Ser Lys Gly Gly Arg Lys Asn Lys Arg
   1               5                  10                  15

 Ala Asn Ser Ser Gly Asp Glu Gln Glu Asn Gly Ala Gly Ala Leu
                  20                  25                  30

 Ala Ala Ala Gly Ala Ala Gly Ala Ala Ala Gly Gly Ala Leu Ala
                  35                  40                  45

 Ala Ala Ala Gly Cys Gly Ala Ala Ala Ala Gly Ala Pro Gly Ala
                  50                  55                  60

 Gly Gly Ala Ala Gly Ala Gly Gly Ala Gly Thr Gly Ala Ala Asn
                  65                  70                  75

 Ala Ala Ala Ala Ala Gly Ala Ala Ala Ala Gly Asp Ala Lys Asn
                  80                  85                  90

 Glu Ala Pro Cys Ala Thr Pro Leu Ile Cys Ser Phe Gly Arg Pro
                  95                 100                 105

 Val Asp Leu Glu Lys Asp Asp Tyr Gln Lys Val Val Cys Asn Asn
                 110                 115                 120

 Glu His Cys Pro Cys Ser Thr Trp Met His Leu Gln Cys Phe Tyr
                 125                 130                 135

 Glu Trp Glu Ser Ser Ile Leu Val Gln Phe Asn Cys Ile Gly Arg
                 140                 145                 150

 Ala Arg Ser Trp Asn Glu Lys Gln Cys Arg Gln Asn Met Trp Thr
                 155                 160                 165

 Lys Lys Gly Tyr Asp Leu Ala Phe Arg Phe Cys Ser Cys Arg Cys
                 170                 175                 180

 Gly Gln Gly His Leu Lys Lys Asp Thr Asp Trp Tyr Gln Val Lys
                 185                 190                 195

 Arg Met Gln Asp Glu Lys Lys Lys Lys Ser Gly Ser Glu Lys Asn
                 200                 205                 210

 Thr Gly Arg Pro Pro Gly Glu Ala Ala Glu Glu Ala Lys Lys Cys
                 215                 220                 225

 Arg Pro Pro Asn Lys Pro Gln Lys Gly Pro Ser His Asp Leu Pro
                 230                 235                 240

 Arg Arg His Ser Met Asp Arg Gln Asn Ser Gln Glu Lys Ala Val
                 245                 250                 255

 Gly Ala Ala Ala Tyr Gly Ala Arg Ser Pro Gly Gly Ser Pro Gly
                 260                 265                 270

 Gln Ser Pro Pro Thr Gly Tyr Ser Ile Leu Ser Pro Ala His Phe
                 275                 280                 285

 Ser Gly Pro Arg Ser Ser Arg Tyr Leu Gly Glu Phe Leu Lys Asn
                 290                 295                 300

 Ala Ile His Leu Glu Pro His Lys Lys Ala Met Ala Gly Gly His
                 305                 310                 315

 Val Phe Arg Asn Ala His Phe Asp Tyr Ser Pro Ala Gly Leu Ala
                 320                 325                 330

 Val His Arg Gly Gly His Phe Asp Thr Pro Val Gln Phe Leu Arg
                 335                 340                 345

 Arg Leu Asp Leu Ser Glu Leu Leu Thr His Ile Pro Arg His Lys
                 350                 355                 360

 Leu Asn Thr Phe His Val Arg Met Glu Asp Asp Ala Gln Val Gly
                 365                 370                 375

 Gln Gly Glu Asp Leu Arg Lys Phe Ile Leu Ala Ala Leu Ser Ala
                 380                 385                 390

 Ser His Arg Asn Val Val Asn Cys Ala Leu Cys His Arg Ala Leu
                 395                 400                 405

 Pro Val Phe Glu Gln Phe Pro Leu Val Asp Gly Thr Leu Phe Leu
                 410                 415                 420

 Ser Pro Ser Arg His Asp Glu Ile Glu Tyr Asp Val Pro Cys His
                 425                 430                 435

 Leu Gln Gly Arg Leu Met His Leu Tyr Ala Val Cys Val Asp Cys
                 440                 445                 450

 Leu Glu Gly Val His Lys Ile Ile Cys Ile Lys Cys Lys Ser Arg
                 455                 460                 465

 Trp Asp Gly Ser Trp His Gln Leu Gly Thr Met Tyr Thr Tyr Asp
                 470                 475                 480

 Ile Leu Ala Ala Ser Pro Cys Cys Gln Ala Arg Leu Asn Cys Lys
                 485                 490                 495

 His Cys Gly Lys Pro Val Ile Asp Val Arg Ile Gly Met Gln Tyr
                 500                 505                 510

 Phe Ser Glu Tyr Ser Asn Val Gln Gln Cys Pro His Cys Gly Asn
                 515                 520                 525

 Leu Asp Tyr His Phe Val Lys Pro Phe Ser Ser Phe Lys Val Leu
                 530                 535                 540

 Glu Ala Tyr


<210> 6052
<211> 4877
<212> DNA
<213> Homo sapien

<400> 6052
 gcccgaaacc cggaagtgag cggcggcagc tgcgaggctc ggagaaacag 50

 gcgccgcggg ctccgcgccc ggccggaccc gggcccgaga tcatgatgct 100

 gccgccaccg ccgccaccac ggagcgagaa gcccagatag acgccccggc 150

 ggccccgggt cctggagtcc cgccgcctgc tgcccggccg aggaccccac 200

 cccgcctgcc gcccgatgct tgcagtgggg cccgccatgg acagggatta 250

 cccgcagcat gaacccccgc cggcgggcag cctcctgtac agcccgccgc 300

 ccctgcagag cgccatgctg cactgcccct actggaacac cttctcgctg 350

 ccgccatacc ctgccttctc cagcgacagc cgcccgttca tgagctccgc 400

 ctccttcctc ggcagccagc cctgcccaga caccagctat gcccccgtgg 450

 ccaccgcctc cagcttgcca ccaaagacct gcgactttgc tcaggactcc 500

 tcctattttg aggacttctc caacatctcc atcttctcct cgtccgtgga 550

 ctccctgtcg gacatcgtgg acacgcccga cttcctgccg gctgacagcc 600

 tcaaccaggt gtccaccatc tgggacgata accctgcccc ctccacccac 650

 gataagctgt tccagctcag caggccgttt gcaggcttcg aggactttct 700

 gccctcccac agcaccccgc ttctcgtcag ctaccaggag cagagtgtgc 750

 agagccagcc agaggaggag gacgaggctg aggaggagga ggcggaggag 800

 ctggggcaca cagagaccta cgccgactac gtgccgtcca agtccaagat 850

 cgggaagcag cacccagacc gcgtggtgga gaccagcaca ctgtccagcg 900

 tcccaccccc agacatcacc tacaccctgg ccctgccctc ggacagcggg 950

 gccctgtctg ccctgcagct agaggccatc acctacgcct gccagcaaca 1000

 cgaggtcctg ctccccagcg ggcagcgcgc gggctttctc atcggcgatg 1050

 gggccggcgt gggcaaaggc cggacggtgg ccggagtcat cctggagaac 1100

 cacctgcgcg gccggaagaa agcattgtgg ttcagcgtct ccaacgacct 1150

 caagtacgat gcggagcgcg acctgcggga catcgaagcc acgggcatcg 1200

 cggtgcacgc gctcagcaag atcaagtacg gtgacaccac tacctcagag 1250

 ggcgtcctct tcgccaccta ctccgccctg attggggaga gccaggccgg 1300

 tggccagcac cgcactcgcc tccggcagat cctggactgg tgtggggagg 1350

 cctttgaggg cgtcatcgtg ttcgacgagt gtcacaaagc caagaatgcc 1400

 ggctccacca agatgggcaa ggccgtgcta gacctgcaga acaagctgcc 1450

 cctggcccgc gtggtctacg ccagcgccac aggtgcctct gagcctcgga 1500

 acatgatcta catgagccgc ttgggtatct ggggcgaggg cacacccttc 1550

 cggaactttg aggagttcct gcacgccatc gagaagaggg gcgttggcgc 1600

 catggagatc gtggccatgg acatgaaggt cagcggcatg tacatcgcac 1650

 gccagctcag cttctccggc gtcaccttcc gcatcgagga gatcccgctg 1700

 gccccagcct tcgagtgcgt ctacaaccgc gcagccctgc tgtgggccga 1750

 ggccctgaac gtgttccagc aggcggccga ctggatcggc ctggagtcgc 1800

 gcaagtccct gtggggccag ttctggtcgg cacaccagcg cttcttcaag 1850

 tatctgtgca tcgcagccaa ggtgcgccgg ctggtggagc tggcccgaga 1900

 ggagctggcg cgagacaagt gcgtggtcat cgggctgcag tccacgggcg 1950

 aggcgcgcac gcgggaggtg ctgggggaga acgatgggca cctcaactgc 2000

 ttcgtctcgg ccgctgaagg cgtgttcctg tcgctaattc agaagcactt 2050

 tccgtccacc aagagaaagc gggacagagg agcgggcagc aagcggaaac 2100

 ggcgacctcg gggacgcggg gccaaagccc cccggctggc gtgcgagaca 2150

 gcgggcgtca tccgcatcag tgacgacagc agcacggagt cggaccctgg 2200

 cctggacagc gacttcaact cctcccccga gtccctggtg gatgacgacg 2250

 ttgtcatcgt tgatgcagtc gggctcccca gtgacgaccg gggatccctg 2300

 tgcctcctgc agagagaccc gcatggcccc ggggtcctgg agcgggtgga 2350

 gcggctgaag caggatctgc tggacaaagt gcgccggctg ggccgggaac 2400

 tgccagtcaa caccctggac gagctcatcg accagctggg cggcccccag 2450

 cgggtggcgg agatgaccgg caggaaaggc cgcgtggtgt ccaggcccga 2500

 cgggacggtg gccttcgagt cgcgggcaga gcagggtctg tccatcgacc 2550

 acgtgaacct cagggagaag cagcgcttca tgagcggcga gaagctcgtg 2600

 gccatcatct cggaggcctc cagctcgggt gtctccctcc aagccgaccg 2650

 ccgtgtccag aaccagcggc gccgcgtgca catgaccttg gagctgccgt 2700

 ggagcgccga ccgcgccatc cagcagttcg gccgcaccca ccggtccaac 2750

 caggtctccg cgccagagta tgtcttcctc atctcggagc tggccgggga 2800

 gcgccggttc gcctccatcg tggccaagcg cctggagagt ctgggggccc 2850

 tgacccacgg agaccgccgc gccacggagt cccgtgacct cagcaagtac 2900

 aactttgaga acaagtatgg cacccgggcc ctgcactgtg tcctcaccac 2950

 catcctgagc cagactgaga acaaagtgcc tgtgccccag ggataccctg 3000

 gaggggtccc caccttcttc cgggacatga agcagggcct gctgtctgtg 3050

 ggcattggtg gccgggagtc ccggaatggc tgcctggacg tggagaagga 3100

 ctgttccatc accaagttcc tgaaccgcat cctggggctg gaggtgcaca 3150

 agcagaatgc cctgttccag tacttctcag acaccttcga ccacctcatc 3200

 gagatggaca agcgggaggg caaatacgac atgggcatcc tggaccttgc 3250

 tcccggtatc gaggagatct acgaggagag ccagcaggtg ttcctggctc 3300

 ccgggcaccc gcaggacggg caggtggtct tctacaagat cagcgtggac 3350

 cgcggcctga agtgggagga cgcctttgcc aagtcgctgg cgctgacggg 3400

 cccctatgac ggcttctacc tctcctacaa ggtccgcggt aacaagccca 3450

 gctgcctgct ggcggagcag aaccgcggcc agttcttcac ggtgtacaag 3500

 cccaacatcg gccggcagag ccagctggag gccctggaca gcctccgccg 3550

 caagttccac cgggtcaccg cggaggaggc caaggagccc tgggagagtg 3600

 gctacgcttt gtcgctgacg cactgcagcc acagcgcctg gaaccggcac 3650

 tgccggctgg cgcaggaggg taaggactgc ctgcaggggc tgcggctgcg 3700

 gcaccactac atgctgtgcg gcgcgctgct gcgcgtgtgg ggccgcatcg 3750

 ccgccgtcat ggccgacgtc agcagcagca gctacctgca gatcgtgcgg 3800

 ctgaagacca aggacaggaa gaagcaagtg ggcatcaaga tccccgaggg 3850

 ctgcgtgcgc cgggtgctgc aggagctgcg gctgatggat gcggacgtga 3900

 agcgcaggca ggcgcccgcc ctgggctgcc ccgccccgcc cgccccgcgc 3950

 ccgctggcgc tgccttgcgg ccccggagag gtgctggacc tcacctacag 4000

 ccccccggcc gaggccttcc cgccgccccc gcacttctct ttcccggcgc 4050

 cgctgtccct ggacgccggc cccggcgtcg tgccgctggg cacccccgac 4100

 gcccaggccg accctgcggc cctcgcgcac cagggctgcg acatcaactt 4150

 caaggaggtg ctggaggaca tgctgcgctc gctgcacgcg gggccgccct 4200

 ccgagggcgc gctgggggag ggcgcggggg cggggggcgc ggcgggcggt 4250

 ggtcccgagc ggcagagcgt gatccagttc agcccaccct tccccggcgc 4300

 ccaggctcct ctctgacacg cctttaggcg aaacatgccc caagacacag 4350

 ggaccgtttc tcccctagga gcagcggtgg ggagcagggc caaggtcccc 4400

 tgaccactgc tcagaggagc cctaggccct ggccgcagtg ccttcagcgc 4450

 ccgacccggg cccccacctg gtcagccctg gcggggccca ctcaggacag 4500

 ctgggggccg gggcgtggca gggccctctc tgtgcctctc ctcctaagta 4550

 ggaaggggct ccgggtggct gctctgggac tgggcaccca caagggctca 4600

 gtgggcccaa acccttgaaa tccgtgaaac cgggtggtcc caagagctag 4650

 aaactcagga aaccccaggt gctcagggcc ccgcgtctcg ggggctccgt 4700

 ggggcagacc cctgctaata tatgcaattc tccctccccc agcccttccc 4750

 tgacccctaa gttattgccc gctcacctct cccaggcccc aggccgcgga 4800

 gctggcaggg tggcgcctgc ggtttctatg tatttatagc aagttctgat 4850

 gtacatatgt aaaggacttt tttaaat 4877

<210> 6053
<211> 1366
<212> PRT
<213> Homo sapien

<400> 6053
 Met Leu Ala Val Gly Pro Ala Met Asp Arg Asp Tyr Pro Gln His
   1               5                  10                  15

 Glu Pro Pro Pro Ala Gly Ser Leu Leu Tyr Ser Pro Pro Pro Leu
                  20                  25                  30

 Gln Ser Ala Met Leu His Cys Pro Tyr Trp Asn Thr Phe Ser Leu
                  35                  40                  45

 Pro Pro Tyr Pro Ala Phe Ser Ser Asp Ser Arg Pro Phe Met Ser
                  50                  55                  60

 Ser Ala Ser Phe Leu Gly Ser Gln Pro Cys Pro Asp Thr Ser Tyr
                  65                  70                  75

 Ala Pro Val Ala Thr Ala Ser Ser Leu Pro Pro Lys Thr Cys Asp
                  80                  85                  90

 Phe Ala Gln Asp Ser Ser Tyr Phe Glu Asp Phe Ser Asn Ile Ser
                  95                 100                 105

 Ile Phe Ser Ser Ser Val Asp Ser Leu Ser Asp Ile Val Asp Thr
                 110                 115                 120

 Pro Asp Phe Leu Pro Ala Asp Ser Leu Asn Gln Val Ser Thr Ile
                 125                 130                 135

 Trp Asp Asp Asn Pro Ala Pro Ser Thr His Asp Lys Leu Phe Gln
                 140                 145                 150

 Leu Ser Arg Pro Phe Ala Gly Phe Glu Asp Phe Leu Pro Ser His
                 155                 160                 165

 Ser Thr Pro Leu Leu Val Ser Tyr Gln Glu Gln Ser Val Gln Ser
                 170                 175                 180

 Gln Pro Glu Glu Glu Asp Glu Ala Glu Glu Glu Glu Ala Glu Glu
                 185                 190                 195

 Leu Gly His Thr Glu Thr Tyr Ala Asp Tyr Val Pro Ser Lys Ser
                 200                 205                 210

 Lys Ile Gly Lys Gln His Pro Asp Arg Val Val Glu Thr Ser Thr
                 215                 220                 225

 Leu Ser Ser Val Pro Pro Pro Asp Ile Thr Tyr Thr Leu Ala Leu
                 230                 235                 240

 Pro Ser Asp Ser Gly Ala Leu Ser Ala Leu Gln Leu Glu Ala Ile
                 245                 250                 255

 Thr Tyr Ala Cys Gln Gln His Glu Val Leu Leu Pro Ser Gly Gln
                 260                 265                 270

 Arg Ala Gly Phe Leu Ile Gly Asp Gly Ala Gly Val Gly Lys Gly
                 275                 280                 285

 Arg Thr Val Ala Gly Val Ile Leu Glu Asn His Leu Arg Gly Arg
                 290                 295                 300

 Lys Lys Ala Leu Trp Phe Ser Val Ser Asn Asp Leu Lys Tyr Asp
                 305                 310                 315

 Ala Glu Arg Asp Leu Arg Asp Ile Glu Ala Thr Gly Ile Ala Val
                 320                 325                 330

 His Ala Leu Ser Lys Ile Lys Tyr Gly Asp Thr Thr Thr Ser Glu
                 335                 340                 345

 Gly Val Leu Phe Ala Thr Tyr Ser Ala Leu Ile Gly Glu Ser Gln
                 350                 355                 360

 Ala Gly Gly Gln His Arg Thr Arg Leu Arg Gln Ile Leu Asp Trp
                 365                 370                 375

 Cys Gly Glu Ala Phe Glu Gly Val Ile Val Phe Asp Glu Cys His
                 380                 385                 390

 Lys Ala Lys Asn Ala Gly Ser Thr Lys Met Gly Lys Ala Val Leu
                 395                 400                 405

 Asp Leu Gln Asn Lys Leu Pro Leu Ala Arg Val Val Tyr Ala Ser
                 410                 415                 420

 Ala Thr Gly Ala Ser Glu Pro Arg Asn Met Ile Tyr Met Ser Arg
                 425                 430                 435

 Leu Gly Ile Trp Gly Glu Gly Thr Pro Phe Arg Asn Phe Glu Glu
                 440                 445                 450

 Phe Leu His Ala Ile Glu Lys Arg Gly Val Gly Ala Met Glu Ile
                 455                 460                 465

 Val Ala Met Asp Met Lys Val Ser Gly Met Tyr Ile Ala Arg Gln
                 470                 475                 480

 Leu Ser Phe Ser Gly Val Thr Phe Arg Ile Glu Glu Ile Pro Leu
                 485                 490                 495

 Ala Pro Ala Phe Glu Cys Val Tyr Asn Arg Ala Ala Leu Leu Trp
                 500                 505                 510

 Ala Glu Ala Leu Asn Val Phe Gln Gln Ala Ala Asp Trp Ile Gly
                 515                 520                 525

 Leu Glu Ser Arg Lys Ser Leu Trp Gly Gln Phe Trp Ser Ala His
                 530                 535                 540

 Gln Arg Phe Phe Lys Tyr Leu Cys Ile Ala Ala Lys Val Arg Arg
                 545                 550                 555

 Leu Val Glu Leu Ala Arg Glu Glu Leu Ala Arg Asp Lys Cys Val
                 560                 565                 570

 Val Ile Gly Leu Gln Ser Thr Gly Glu Ala Arg Thr Arg Glu Val
                 575                 580                 585

 Leu Gly Glu Asn Asp Gly His Leu Asn Cys Phe Val Ser Ala Ala
                 590                 595                 600

 Glu Gly Val Phe Leu Ser Leu Ile Gln Lys His Phe Pro Ser Thr
                 605                 610                 615

 Lys Arg Lys Arg Asp Arg Gly Ala Gly Ser Lys Arg Lys Arg Arg
                 620                 625                 630

 Pro Arg Gly Arg Gly Ala Lys Ala Pro Arg Leu Ala Cys Glu Thr
                 635                 640                 645

 Ala Gly Val Ile Arg Ile Ser Asp Asp Ser Ser Thr Glu Ser Asp
                 650                 655                 660

 Pro Gly Leu Asp Ser Asp Phe Asn Ser Ser Pro Glu Ser Leu Val
                 665                 670                 675

 Asp Asp Asp Val Val Ile Val Asp Ala Val Gly Leu Pro Ser Asp
                 680                 685                 690

 Asp Arg Gly Ser Leu Cys Leu Leu Gln Arg Asp Pro His Gly Pro
                 695                 700                 705

 Gly Val Leu Glu Arg Val Glu Arg Leu Lys Gln Asp Leu Leu Asp
                 710                 715                 720

 Lys Val Arg Arg Leu Gly Arg Glu Leu Pro Val Asn Thr Leu Asp
                 725                 730                 735

 Glu Leu Ile Asp Gln Leu Gly Gly Pro Gln Arg Val Ala Glu Met
                 740                 745                 750

 Thr Gly Arg Lys Gly Arg Val Val Ser Arg Pro Asp Gly Thr Val
                 755                 760                 765

 Ala Phe Glu Ser Arg Ala Glu Gln Gly Leu Ser Ile Asp His Val
                 770                 775                 780

 Asn Leu Arg Glu Lys Gln Arg Phe Met Ser Gly Glu Lys Leu Val
                 785                 790                 795

 Ala Ile Ile Ser Glu Ala Ser Ser Ser Gly Val Ser Leu Gln Ala
                 800                 805                 810

 Asp Arg Arg Val Gln Asn Gln Arg Arg Arg Val His Met Thr Leu
                 815                 820                 825

 Glu Leu Pro Trp Ser Ala Asp Arg Ala Ile Gln Gln Phe Gly Arg
                 830                 835                 840

 Thr His Arg Ser Asn Gln Val Ser Ala Pro Glu Tyr Val Phe Leu
                 845                 850                 855

 Ile Ser Glu Leu Ala Gly Glu Arg Arg Phe Ala Ser Ile Val Ala
                 860                 865                 870

 Lys Arg Leu Glu Ser Leu Gly Ala Leu Thr His Gly Asp Arg Arg
                 875                 880                 885

 Ala Thr Glu Ser Arg Asp Leu Ser Lys Tyr Asn Phe Glu Asn Lys
                 890                 895                 900

 Tyr Gly Thr Arg Ala Leu His Cys Val Leu Thr Thr Ile Leu Ser
                 905                 910                 915

 Gln Thr Glu Asn Lys Val Pro Val Pro Gln Gly Tyr Pro Gly Gly
                 920                 925                 930

 Val Pro Thr Phe Phe Arg Asp Met Lys Gln Gly Leu Leu Ser Val
                 935                 940                 945

 Gly Ile Gly Gly Arg Glu Ser Arg Asn Gly Cys Leu Asp Val Glu
                 950                 955                 960

 Lys Asp Cys Ser Ile Thr Lys Phe Leu Asn Arg Ile Leu Gly Leu
                 965                 970                 975

 Glu Val His Lys Gln Asn Ala Leu Phe Gln Tyr Phe Ser Asp Thr
                 980                 985                 990

 Phe Asp His Leu Ile Glu Met Asp Lys Arg Glu Gly Lys Tyr Asp
                 995                1000                1005

 Met Gly Ile Leu Asp Leu Ala Pro Gly Ile Glu Glu Ile Tyr Glu
                1010                1015                1020

 Glu Ser Gln Gln Val Phe Leu Ala Pro Gly His Pro Gln Asp Gly
                1025                1030                1035

 Gln Val Val Phe Tyr Lys Ile Ser Val Asp Arg Gly Leu Lys Trp
                1040                1045                1050

 Glu Asp Ala Phe Ala Lys Ser Leu Ala Leu Thr Gly Pro Tyr Asp
                1055                1060                1065

 Gly Phe Tyr Leu Ser Tyr Lys Val Arg Gly Asn Lys Pro Ser Cys
                1070                1075                1080

 Leu Leu Ala Glu Gln Asn Arg Gly Gln Phe Phe Thr Val Tyr Lys
                1085                1090                1095

 Pro Asn Ile Gly Arg Gln Ser Gln Leu Glu Ala Leu Asp Ser Leu
                1100                1105                1110

 Arg Arg Lys Phe His Arg Val Thr Ala Glu Glu Ala Lys Glu Pro
                1115                1120                1125

 Trp Glu Ser Gly Tyr Ala Leu Ser Leu Thr His Cys Ser His Ser
                1130                1135                1140

 Ala Trp Asn Arg His Cys Arg Leu Ala Gln Glu Gly Lys Asp Cys
                1145                1150                1155

 Leu Gln Gly Leu Arg Leu Arg His His Tyr Met Leu Cys Gly Ala
                1160                1165                1170

 Leu Leu Arg Val Trp Gly Arg Ile Ala Ala Val Met Ala Asp Val
                1175                1180                1185

 Ser Ser Ser Ser Tyr Leu Gln Ile Val Arg Leu Lys Thr Lys Asp
                1190                1195                1200

 Arg Lys Lys Gln Val Gly Ile Lys Ile Pro Glu Gly Cys Val Arg
                1205                1210                1215

 Arg Val Leu Gln Glu Leu Arg Leu Met Asp Ala Asp Val Lys Arg
                1220                1225                1230

 Arg Gln Ala Pro Ala Leu Gly Cys Pro Ala Pro Pro Ala Pro Arg
                1235                1240                1245

 Pro Leu Ala Leu Pro Cys Gly Pro Gly Glu Val Leu Asp Leu Thr
                1250                1255                1260

 Tyr Ser Pro Pro Ala Glu Ala Phe Pro Pro Pro Pro His Phe Ser
                1265                1270                1275

 Phe Pro Ala Pro Leu Ser Leu Asp Ala Gly Pro Gly Val Val Pro
                1280                1285                1290

 Leu Gly Thr Pro Asp Ala Gln Ala Asp Pro Ala Ala Leu Ala His
                1295                1300                1305

 Gln Gly Cys Asp Ile Asn Phe Lys Glu Val Leu Glu Asp Met Leu
                1310                1315                1320

 Arg Ser Leu His Ala Gly Pro Pro Ser Glu Gly Ala Leu Gly Glu
                1325                1330                1335

 Gly Ala Gly Ala Gly Gly Ala Ala Gly Gly Gly Pro Glu Arg Gln
                1340                1345                1350

 Ser Val Ile Gln Phe Ser Pro Pro Phe Pro Gly Ala Gln Ala Pro
                1355                1360                1365

 Leu


<210> 6054
<211> 1548
<212> DNA
<213> Homo sapien

<400> 6054
 caacatggcg gccgcggtgg cggcggcacc tggggccttg ggatccctgc 50

 atgctggcgg cgcccgcctg gtggccgctt gcagtgcgtg gctctgcccg 100

 gggttgaggc tgcccggctc gttggcaggc cggcgagcgg gcccggcgat 150

 ctgggcccag ggctgggtac ctgcggccgg gggtcccgcc ccgaaaaggg 200

 gctacagctc tgagatgaag acggaggacg agctgcgggt gcggcacctg 250

 gaggaggaga accgaggaat tgtggtgctt ggaataaaca gagcttatgg 300

 caaaaattca ctcagtaaaa atcttataaa aatgctatca aaagctgtgg 350

 atgctttgaa atctgataag aaagtacgga ccataataat caggagtgaa 400

 gtcccaggga tattctgtgc tggtgctgac cttaaggaaa gagccaaaat 450

 gagttccagt gaagttggtc cttttgtctc caaaataaga gcagtgatta 500

 acgatattgc taatcttcca gtgccaacaa ttgcagcaat agatggactc 550

 gctttaggtg gtggtcttga actggcttta gcctgtgata tacgagtagc 600

 agcttcctct gcaaaaatgg gcctggttga aacaaaattg gcgattattc 650

 ctggtggagg ggggacacag cgattgccac gcgccattgg aatgtccctg 700

 gccaaggagc tcatattctc tgcgcgagtc ctcgatggca aagaagccaa 750

 agcagtgggc ttaatcagcc acgttctgga acagaaccag gagggagacg 800

 cggcctacag gaaggccttg gacctggcga gagagttttt acctcaggga 850

 cctgttgcaa tgagagtggc aaaattagca attaatcaag ggatggaggt 900

 cgatttagta acagggttag ccatagaaga agcttgttat gctcagacca 950

 ttccaacaaa agacagactt gaaggtcttc ttgcttttaa agagaaaagg 1000

 ccccctcgct ataaaggaga ataaaaggaa cagaaattct taagatgcca 1050

 atgtaataaa tgtacttcct ggaagtgtct ttcggatcca ctatatgcct 1100

 cagcacatgg aaccttaatg accaaagtga agagcagatt attcatacgg 1150

 tgtaataagc gtctggaatg gacccatccg tgtacttcat tcaaatgtgt 1200

 aaatgtcata ttcattcaga tttataaagc tagtagtgta tagtcagaaa 1250

 cagaatcaaa gttagatata catttttaaa tatttactgc atatgaggct 1300

 ttctgttaat tttttaatgt gaataattta tatattgcac attctaggaa 1350

 taatattgat tgtatgtcta ctgtgctgca ttaagaaaat aaaatttcta 1400

 tataccaaaa atgtgaagtt ataccaaata aagtttctaa gtgattaatg 1450

 catacgaaca gctacatata catatatcta aacctgaaaa atgaattgat 1500

 attctgagtg aaaactacct aatataaata aaattagtga aaagaaaa 1548

<210> 6055
<211> 339
<212> PRT
<213> Homo sapien

<400> 6055
 Met Ala Ala Ala Val Ala Ala Ala Pro Gly Ala Leu Gly Ser Leu
   1               5                  10                  15

 His Ala Gly Gly Ala Arg Leu Val Ala Ala Cys Ser Ala Trp Leu
                  20                  25                  30

 Cys Pro Gly Leu Arg Leu Pro Gly Ser Leu Ala Gly Arg Arg Ala
                  35                  40                  45

 Gly Pro Ala Ile Trp Ala Gln Gly Trp Val Pro Ala Ala Gly Gly
                  50                  55                  60

 Pro Ala Pro Lys Arg Gly Tyr Ser Ser Glu Met Lys Thr Glu Asp
                  65                  70                  75

 Glu Leu Arg Val Arg His Leu Glu Glu Glu Asn Arg Gly Ile Val
                  80                  85                  90

 Val Leu Gly Ile Asn Arg Ala Tyr Gly Lys Asn Ser Leu Ser Lys
                  95                 100                 105

 Asn Leu Ile Lys Met Leu Ser Lys Ala Val Asp Ala Leu Lys Ser
                 110                 115                 120

 Asp Lys Lys Val Arg Thr Ile Ile Ile Arg Ser Glu Val Pro Gly
                 125                 130                 135

 Ile Phe Cys Ala Gly Ala Asp Leu Lys Glu Arg Ala Lys Met Ser
                 140                 145                 150

 Ser Ser Glu Val Gly Pro Phe Val Ser Lys Ile Arg Ala Val Ile
                 155                 160                 165

 Asn Asp Ile Ala Asn Leu Pro Val Pro Thr Ile Ala Ala Ile Asp
                 170                 175                 180

 Gly Leu Ala Leu Gly Gly Gly Leu Glu Leu Ala Leu Ala Cys Asp
                 185                 190                 195

 Ile Arg Val Ala Ala Ser Ser Ala Lys Met Gly Leu Val Glu Thr
                 200                 205                 210

 Lys Leu Ala Ile Ile Pro Gly Gly Gly Gly Thr Gln Arg Leu Pro
                 215                 220                 225

 Arg Ala Ile Gly Met Ser Leu Ala Lys Glu Leu Ile Phe Ser Ala
                 230                 235                 240

 Arg Val Leu Asp Gly Lys Glu Ala Lys Ala Val Gly Leu Ile Ser
                 245                 250                 255

 His Val Leu Glu Gln Asn Gln Glu Gly Asp Ala Ala Tyr Arg Lys
                 260                 265                 270

 Ala Leu Asp Leu Ala Arg Glu Phe Leu Pro Gln Gly Pro Val Ala
                 275                 280                 285

 Met Arg Val Ala Lys Leu Ala Ile Asn Gln Gly Met Glu Val Asp
                 290                 295                 300

 Leu Val Thr Gly Leu Ala Ile Glu Glu Ala Cys Tyr Ala Gln Thr
                 305                 310                 315

 Ile Pro Thr Lys Asp Arg Leu Glu Gly Leu Leu Ala Phe Lys Glu
                 320                 325                 330

 Lys Arg Pro Pro Arg Tyr Lys Gly Glu
                 335

<210> 6056
<211> 2965
<212> DNA
<213> Homo sapien

<400> 6056
 ggcacgaggc tgctttcttt ttcctttctt cggaatgaga gactcaacca 50

 taatagaaag aatggagaac tattaaccac cattcttcag tgggctgtga 100

 ttttcagagg ggaatactaa gaaatggttt tccatactgg aacccaaagg 150

 taaagacact caaggacaga catttttggc agagcataga tgaaaatggc 200

 aagttccctg gctttccttc tgctcaactt tcatgtctcc ctcttcttgg 250

 tccagctgct cactccttgc tcagctcagt tttctgtgct tggaccctct 300

 gggcccatcc tggccatggt gggtgaagac gctgatctgc cctgtcacct 350

 gttcccgacc atgagtgcag agaccatgga gctgaggtgg gtgagttcca 400

 gcctaaggca ggtggtgaac gtgtatgcag atggaaagga agtggaagac 450

 aggcagagtg caccgtatcg agggagaact tcgattctgc gggatggcat 500

 cactgcaggg aaggctgctc tccgaataca caacgtcaca gcctctgaca 550

 gtggaaagta cttgtgttat ttccaagatg gtgacttcta cgaaaaagcc 600

 ctggtggagc tgaaggttgc agcattgggt tctgatcttc acattgaagt 650

 gaagggttat gaggatggag ggatccatct ggagtgcagg tccactggct 700

 ggtaccccca accccaaata aagtggagcg acaccaaggg agagaacatc 750

 ccggctgtgg aagcacctgt ggttgcagat ggagtgggcc tgtatgcagt 800

 agcagcatct gtgatcatga gaggcagctc tggtgggggt gtatcctgca 850

 tcatcagaaa ttccctcctc ggcctggaaa agacagccag catatccatc 900

 gcagacccct tcttcaggag cgcccagccc tggatcgcgg ccctggcagg 950

 gaccctgcct atctcgttgc tgcttctcgc aggagccagt tacttcttgt 1000

 ggagacaaca gaaggaaaaa attgctctgt ccagggagac agaaagagag 1050

 cgagagatga aagaaatggg atacgctgca acagagcaag aaataagcct 1100

 aagagagaag ctccaggagg aactcaagtg gaggaaaatc cagtacatgg 1150

 ctcgtggaga gaagtctttg gcctatcatg aatggaaaat ggccctcttc 1200

 aaacctgcgg atgtgattct ggatccagac acggcaaacg ccatcctcct 1250

 tgtttctgag gaccagagga gtgtgcagcg tgctgaagag ccgcgggatc 1300

 tgccagacaa ccctgagaga tttgaatggc gttactgtgt ccttggctgt 1350

 gaaaacttca catcagggag acattactgg gaggtggaag tgggggacag 1400

 aaaagagtgg catattgggg tatgtagtaa gaacgtggag aggaaaaaag 1450

 gttgggtcaa aatgacaccg gagaacggat actggactat gggcctgact 1500

 gatgggaata agtatcgggc tctcactgag cccagaacca acctgaaact 1550

 tcctgagcct cctaggaaag tggggatctt cctggactat gagactggag 1600

 agatctcgtt ctataatgcc acagatggat ctcatatcta cacctttccg 1650

 cacgcctctt tctctgagcc tctatatcct gttttcagaa ttttgacctt 1700

 ggagcccact gccctgacca tttgcccaat accaaaagaa gtagagagtt 1750

 cccccgatcc tgacctagtg cctgatcatt ccctggagac accactgacc 1800

 ccgggcttag ctaatgaaag tggggagcct caggctgaag taacatctct 1850

 gcttctccct gcccaccctg gagctgaggt ctccccttct gcaacaacca 1900

 atcagaacca taagctacag gcacgcactg aagcacttta ctgatattca 1950

 ttccattatt ccatatgaca gttgttttga gtttcgtacc accttattgt 2000

 ccccttatac agataaggaa actggggtgc agaaaggtga attaacttta 2050

 caaagtagac atgacaagtg aacagcagag ctgggatcta aacagcaata 2100

 actaacatta acagagaatt taaaatgttc ttagtgctgt gttataagct 2150

 ttggtggatg tcactccttt aatcctcaca acaccctgtc gggtagtcat 2200

 attttgcaag tatggaagct gaggcagggc aacatgaagt aacttacata 2250

 actcatacag taatttgtgc agttgggaga tgttcagcct tagtccctgg 2300

 ctaattgcct gttcttttcc agcctgattt tttttcccac aggaagagcc 2350

 cacatgtagc cctgaggttt ccttcccagg acagctgcag ggtagagatc 2400

 attttaagtg cttgtggagt tgacatccct attgactctt tcccagctga 2450

 tatcagagac ttagacccag cactccttgg attagctctg cagagtgtct 2500

 tggttgagag aataacctca tagtaccaac atgacatgtg acttggaaag 2550

 agactagagg ccacacttga taaatcatgg ggcacagata tgttcccacc 2600

 caacaaatgt gataagtgat tgtgcagcca gagccagcct tccttcaatc 2650

 aaggtttcca ggcagagcaa ataccctaga gattctctgt gatataggaa 2700

 atttggatca aggaagctaa aagaattaca gggatgtttt taatcccact 2750

 atggactcag tctcctggaa ataggtctgt ccactcctgg tcattggtgg 2800

 atgttaaacc catattcctt tcaactgctg cctgctaggg aaaactgctc 2850

 ctcattatca tcactattat tgctcaccac tgtatcccct ctacttggca 2900

 agtggttgtc aagttctagt tgttcaataa atgtgttaat aatgcttaaa 2950

 aaaaaaaaaa aaaaa 2965

<210> 6057
<211> 584
<212> PRT
<213> Homo sapien

<400> 6057
 Met Lys Met Ala Ser Ser Leu Ala Phe Leu Leu Leu Asn Phe His
   1               5                  10                  15

 Val Ser Leu Phe Leu Val Gln Leu Leu Thr Pro Cys Ser Ala Gln
                  20                  25                  30

 Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly
                  35                  40                  45

 Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala
                  50                  55                  60

 Glu Thr Met Glu Leu Arg Trp Val Ser Ser Ser Leu Arg Gln Val
                  65                  70                  75

 Val Asn Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser
                  80                  85                  90

 Ala Pro Tyr Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr
                  95                 100                 105

 Ala Gly Lys Ala Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp
                 110                 115                 120

 Ser Gly Lys Tyr Leu Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu
                 125                 130                 135

 Lys Ala Leu Val Glu Leu Lys Val Ala Ala Leu Gly Ser Asp Leu
                 140                 145                 150

 His Ile Glu Val Lys Gly Tyr Glu Asp Gly Gly Ile His Leu Glu
                 155                 160                 165

 Cys Arg Ser Thr Gly Trp Tyr Pro Gln Pro Gln Ile Lys Trp Ser
                 170                 175                 180

 Asp Thr Lys Gly Glu Asn Ile Pro Ala Val Glu Ala Pro Val Val
                 185                 190                 195

 Ala Asp Gly Val Gly Leu Tyr Ala Val Ala Ala Ser Val Ile Met
                 200                 205                 210

 Arg Gly Ser Ser Gly Gly Gly Val Ser Cys Ile Ile Arg Asn Ser
                 215                 220                 225

 Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile Ala Asp Pro
                 230                 235                 240

 Phe Phe Arg Ser Ala Gln Pro Trp Ile Ala Ala Leu Ala Gly Thr
                 245                 250                 255

 Leu Pro Ile Ser Leu Leu Leu Leu Ala Gly Ala Ser Tyr Phe Leu
                 260                 265                 270

 Trp Arg Gln Gln Lys Glu Lys Ile Ala Leu Ser Arg Glu Thr Glu
                 275                 280                 285

 Arg Glu Arg Glu Met Lys Glu Met Gly Tyr Ala Ala Thr Glu Gln
                 290                 295                 300

 Glu Ile Ser Leu Arg Glu Lys Leu Gln Glu Glu Leu Lys Trp Arg
                 305                 310                 315

 Lys Ile Gln Tyr Met Ala Arg Gly Glu Lys Ser Leu Ala Tyr His
                 320                 325                 330

 Glu Trp Lys Met Ala Leu Phe Lys Pro Ala Asp Val Ile Leu Asp
                 335                 340                 345

 Pro Asp Thr Ala Asn Ala Ile Leu Leu Val Ser Glu Asp Gln Arg
                 350                 355                 360

 Ser Val Gln Arg Ala Glu Glu Pro Arg Asp Leu Pro Asp Asn Pro
                 365                 370                 375

 Glu Arg Phe Glu Trp Arg Tyr Cys Val Leu Gly Cys Glu Asn Phe
                 380                 385                 390

 Thr Ser Gly Arg His Tyr Trp Glu Val Glu Val Gly Asp Arg Lys
                 395                 400                 405

 Glu Trp His Ile Gly Val Cys Ser Lys Asn Val Glu Arg Lys Lys
                 410                 415                 420

 Gly Trp Val Lys Met Thr Pro Glu Asn Gly Tyr Trp Thr Met Gly
                 425                 430                 435

 Leu Thr Asp Gly Asn Lys Tyr Arg Ala Leu Thr Glu Pro Arg Thr
                 440                 445                 450

 Asn Leu Lys Leu Pro Glu Pro Pro Arg Lys Val Gly Ile Phe Leu
                 455                 460                 465

 Asp Tyr Glu Thr Gly Glu Ile Ser Phe Tyr Asn Ala Thr Asp Gly
                 470                 475                 480

 Ser His Ile Tyr Thr Phe Pro His Ala Ser Phe Ser Glu Pro Leu
                 485                 490                 495

 Tyr Pro Val Phe Arg Ile Leu Thr Leu Glu Pro Thr Ala Leu Thr
                 500                 505                 510

 Ile Cys Pro Ile Pro Lys Glu Val Glu Ser Ser Pro Asp Pro Asp
                 515                 520                 525

 Leu Val Pro Asp His Ser Leu Glu Thr Pro Leu Thr Pro Gly Leu
                 530                 535                 540

 Ala Asn Glu Ser Gly Glu Pro Gln Ala Glu Val Thr Ser Leu Leu
                 545                 550                 555

 Leu Pro Ala His Pro Gly Ala Glu Val Ser Pro Ser Ala Thr Thr
                 560                 565                 570

 Asn Gln Asn His Lys Leu Gln Ala Arg Thr Glu Ala Leu Tyr
                 575                 580

<210> 6058
<211> 2504
<212> DNA
<213> Homo sapien

<400> 6058
 ctttgccgtc cggctattag cctactgtgg ctagtcaccc ccggggtccc 50

 ggccttctcg ggctggggcc gccgccaccg cggcaggacg gggaggcggg 100

 ccatggcgtc ctgcgtgggg agccggaccc taagcaagga tgatgtgaac 150

 tacaaaatgc atttccggat gatcaacgag cagcaagtgg aggacatcac 200

 cattgacttc ttctaccggc cgcataccat caccctgctc agcttcacca 250

 tcgtcagcct catgtacttc gcctttacca gggatgactc tgttccagaa 300

 gacaacatct ggagaggcat cctctctgtt attttcttct ttcttatcat 350

 cagtgtgtta gctttcccca atggtccgtt cactcgacct catccagcct 400

 tatggcgaat ggtttttgga ctcagtgtgc tctacttcct gttcctggta 450

 ttcctactct tcctgaattt cgagcaggtt aaatctctaa tgtattggct 500

 agatccaaat cttcgatacg ccacaaggga agcagatgtc atggagtatg 550

 ctgtgaactg ccatgtgatc acctgggaga ggattatcag ccactttgat 600

 atttttgcat ttggacattt ctggggctgg gccatgaagg ccttgctgat 650

 ccgtagttac ggtctctgct ggacaatcag tattacctgg gagctgactg 700

 agctcttctt catgcatctc ctccccaatt ttgccgagtg ctggtgggat 750

 caagtcattc tggacatcct gttgtgcaat ggcggtggca tttggctggg 800

 catggtcgtt tgccggtttt tagagatgag gacttaccac tgggcaagct 850

 tcaaggacat tcataccacc accgggaaga tcaagagagc tgttctgcag 900

 ttcactcctg ctagctggac ctatgttcga tggtttgacc ccaaatcttc 950

 ttttcagaga gtagctggag tgtacctttt catgatcatc tggcagctga 1000

 ctgagttgaa taccttcttc ttgaagcata tctttgtgtt ccaagccagt 1050

 catccattaa gttggggtag aattctcttt attggtggca tcacagctcc 1100

 cacagtgaga cagtactacg cttacctcac cgacacacag tgcaagcgcg 1150

 taggaacaca atgctgggtg tttggggtca ttggtttcct ggaggccatt 1200

 gtttgcataa aatttggaca agatctcttc tctaagaccc aaatactcta 1250

 tgttgtgctt tggcttcttt gcgtggcttt caccactttc ctctgtctgt 1300

 acggcatgat ttggtatgca gaacactatg gtcaccgaga aaagacctac 1350

 tcggagtgtg aagatggcac ctacagtcca gagatctcct ggcatcacag 1400

 gaaagggaca aaaggttctg aagacagccc acccaagcat gcaggcaaca 1450

 acgaaagcca ttcttccagg agaaggaatc ggcattccaa gtcaaaagtc 1500

 accaatggcg ttggaaagaa atgaaaaacc ctggttaatc aaagatgttc 1550

 cagagtgcct agaactgaga gggaaatgga actcatttgg aactccccgt 1600

 gaggaggtcg aggcgcacag ggcaagcagg aagaggcgag ggcacttggg 1650

 ggtcattatt tgagatcgta agtcttgttt cccacagacc tggccgcgtc 1700

 aggcagatca tcgcctgggg ggcctttgcc aacgtggggt ctcttctaac 1750

 ttcagcactt gacatgcggt caccggtggc agcgcggtgt gttgaaggga 1800

 aacggtagct attcattcac agttgccaag agcagctccg cgcctgctgg 1850

 atcgtggatg cagcgtaaac atcttccttc agacgaggca ttaaccccat 1900

 ggttaatgga ctggtcacca gtttttattt tatttttatg aatctacctt 1950

 tccattgatt gatttaagtt caggccactt ttctgtcttt tatttggtta 2000

 ctgttgttat ttgtttttaa gttaggatgc tttttaacag cctttagaag 2050

 ccgctgctga aattgatact gggggaaggg ttccccttcc ttctagagca 2100

 gaaaagggag agaagtgttg tattcctgtt tggtaacctc agtctcctgt 2150

 aagacctcct accacatggc gagtatacac caatcaggag agggtagctg 2200

 cctgcatagg agcctcgctt ccgattattc ccttcccaat attattcatc 2250

 cagacttagc cacagtgcac aaaagcaaac ctgctagaga ggcagtgaac 2300

 accacagctt ctccccagct tggtgccttt tacatcgggt ttgttctcct 2350

 tccatggtgt gttgctgaca ttgtcactga gtcccatgtg aggtgctggt 2400

 gagtattacc tttcatctgt gccatgctct agaaccttga ccttgatagt 2450

 tcaccacgtc tgatggatcc ctgttttaaa taaaaacgat tcactttaaa 2500

 gcct 2504

<210> 6059
<211> 473
<212> PRT
<213> Homo sapien

<400> 6059
 Met Ala Ser Cys Val Gly Ser Arg Thr Leu Ser Lys Asp Asp Val
   1               5                  10                  15

 Asn Tyr Lys Met His Phe Arg Met Ile Asn Glu Gln Gln Val Glu
                  20                  25                  30

 Asp Ile Thr Ile Asp Phe Phe Tyr Arg Pro His Thr Ile Thr Leu
                  35                  40                  45

 Leu Ser Phe Thr Ile Val Ser Leu Met Tyr Phe Ala Phe Thr Arg
                  50                  55                  60

 Asp Asp Ser Val Pro Glu Asp Asn Ile Trp Arg Gly Ile Leu Ser
                  65                  70                  75

 Val Ile Phe Phe Phe Leu Ile Ile Ser Val Leu Ala Phe Pro Asn
                  80                  85                  90

 Gly Pro Phe Thr Arg Pro His Pro Ala Leu Trp Arg Met Val Phe
                  95                 100                 105

 Gly Leu Ser Val Leu Tyr Phe Leu Phe Leu Val Phe Leu Leu Phe
                 110                 115                 120

 Leu Asn Phe Glu Gln Val Lys Ser Leu Met Tyr Trp Leu Asp Pro
                 125                 130                 135

 Asn Leu Arg Tyr Ala Thr Arg Glu Ala Asp Val Met Glu Tyr Ala
                 140                 145                 150

 Val Asn Cys His Val Ile Thr Trp Glu Arg Ile Ile Ser His Phe
                 155                 160                 165

 Asp Ile Phe Ala Phe Gly His Phe Trp Gly Trp Ala Met Lys Ala
                 170                 175                 180

 Leu Leu Ile Arg Ser Tyr Gly Leu Cys Trp Thr Ile Ser Ile Thr
                 185                 190                 195

 Trp Glu Leu Thr Glu Leu Phe Phe Met His Leu Leu Pro Asn Phe
                 200                 205                 210

 Ala Glu Cys Trp Trp Asp Gln Val Ile Leu Asp Ile Leu Leu Cys
                 215                 220                 225

 Asn Gly Gly Gly Ile Trp Leu Gly Met Val Val Cys Arg Phe Leu
                 230                 235                 240

 Glu Met Arg Thr Tyr His Trp Ala Ser Phe Lys Asp Ile His Thr
                 245                 250                 255

 Thr Thr Gly Lys Ile Lys Arg Ala Val Leu Gln Phe Thr Pro Ala
                 260                 265                 270

 Ser Trp Thr Tyr Val Arg Trp Phe Asp Pro Lys Ser Ser Phe Gln
                 275                 280                 285

 Arg Val Ala Gly Val Tyr Leu Phe Met Ile Ile Trp Gln Leu Thr
                 290                 295                 300

 Glu Leu Asn Thr Phe Phe Leu Lys His Ile Phe Val Phe Gln Ala
                 305                 310                 315

 Ser His Pro Leu Ser Trp Gly Arg Ile Leu Phe Ile Gly Gly Ile
                 320                 325                 330

 Thr Ala Pro Thr Val Arg Gln Tyr Tyr Ala Tyr Leu Thr Asp Thr
                 335                 340                 345

 Gln Cys Lys Arg Val Gly Thr Gln Cys Trp Val Phe Gly Val Ile
                 350                 355                 360

 Gly Phe Leu Glu Ala Ile Val Cys Ile Lys Phe Gly Gln Asp Leu
                 365                 370                 375

 Phe Ser Lys Thr Gln Ile Leu Tyr Val Val Leu Trp Leu Leu Cys
                 380                 385                 390

 Val Ala Phe Thr Thr Phe Leu Cys Leu Tyr Gly Met Ile Trp Tyr
                 395                 400                 405

 Ala Glu His Tyr Gly His Arg Glu Lys Thr Tyr Ser Glu Cys Glu
                 410                 415                 420

 Asp Gly Thr Tyr Ser Pro Glu Ile Ser Trp His His Arg Lys Gly
                 425                 430                 435

 Thr Lys Gly Ser Glu Asp Ser Pro Pro Lys His Ala Gly Asn Asn
                 440                 445                 450

 Glu Ser His Ser Ser Arg Arg Arg Asn Arg His Ser Lys Ser Lys
                 455                 460                 465

 Val Thr Asn Gly Val Gly Lys Lys
                 470

<210> 6060
<211> 2225
<212> DNA
<213> Homo sapien

<400> 6060
 acgcgtccga tttaaagcta cattgtcagc agaagtatat aggatacttt 50

 cagcgcaagg gacagaaccc ttggtgctct tcaaggaagg tgctgttcgt 100

 ggtttagagg ccttgcttgc agacccccag cagaaaattg aaactgttat 150

 ctctgatgaa gaagtgatta aatggacaaa gtttttcgta gtattcagac 200

 atcctgtttt aatttttatt actgaaaaac atggaaatta ctttgcttac 250

 gtgcaaatgt ttaactcacg tatcttaacc aaatatacac tcttacttgg 300

 acaagacgaa aactctgtta taaagagttt tactgcatct gtagatcgga 350

 aattcatctc tttgatgtca ttaagctctg atggttgtat atatgaaacc 400

 ttgataccaa tacgtccagc tgacccagaa aaaaatcaga gcttagttaa 450

 atcactgctg ctcaaggctg ttgtatctgg taacgctcga aatggagttg 500

 cactcactgc cctggatcag gatcacgtcg cagtcctagg aagtccacta 550

 gcagcttcta aggaatgcct ctctgtatgg aacataaaat ttcaaacact 600

 acagacttca aaagagttac cacaagggac cagtggtcaa ctctggtatt 650

 atggagaaca tttgtttatg ctacatggaa aatctctaac tgtgattcca 700

 tacaagtgtg aagtgtcatc attagcaggt gctcttggaa aactcaagca 750

 tagtcaagat ccaggaactc atgtcgtgtc ccattttgta aactgggaga 800

 cacctcaagg atgtggactt gggttccaga actcagagca gtcaagaaga 850

 attgagacga aaaattgaag tgagtttaca gccagaggtt ccaccatcca 900

 aacaactttt gtcaaccata atgaaagatt cagaaaaaca cattgaagta 950

 gaagtacgga aatttttggc tctgaagcag acacctgact ttcatactgt 1000

 cattggggac acagtaacag gacttctgga aaggtgtaaa gcagaaccat 1050

 cattttatcc ccggaactgt ctgatgcagc ttatccaaac gcatgtgctt 1100

 tcttacagtt tgtgccccga cttaatggag attgccttaa aaaagaaaga 1150

 tgtacagttg ttacaactct gtctacagca gttccctgac attcctgaat 1200

 cagtcacctg tgcttgctta aaaattttct tgagcattgg tgatgacagt 1250

 cttcaagaaa cagatgttaa tatggagtca gtttttgact atagtataaa 1300

 ttctgtacat gatgagaaaa tggaagagca aactgaaatt cttcaaaatg 1350

 gcttcaatcc tgaagaagat aaatgcaata actgtgatca agagttaaat 1400

 aaaaagcccc aggacgaaac aaaggagagc acttcatgcc ctgtggtaca 1450

 aaaaagagca gctctactta atgcaattct tcattcagca tatagcgaga 1500

 catttcttct gcctcatttg aaagacatcc cagcacagca tatcacgctg 1550

 tttcttaagt atttgtattt cctgtacctg aagtgtagcg aaaatgctac 1600

 tatgactctt cctggaatac acccacctac cttgaaccag attatggatt 1650

 ggatatgtct acttctggat gcaaatttta ctgttgttgt aatgatgcca 1700

 gaagcaaaga ggctactgat aaatctttac aagcttgtaa aatctcagat 1750

 atctgtttat tctgagctca acaagattga agtaagtttt cgggagctac 1800

 agaaattaaa tcaagaaaag aataatagag gattatattc aattgaagtg 1850

 ctggagctct tctgatatta tcaattctcc ttcatagaca ttttataaag 1900

 ctcttttatg tgaactcttg cttcatccag gcaagaacgg tgttttgttt 1950

 gcgaccatct cagtgtcaag agaaacgtgt cagtgagtac ctggaccatc 2000

 acttaactga tgctccgggg taggactgca ggtttcacat gaacctgttc 2050

 taggctgtgg acattggtgt ggagaggttc tgcaattttt taaaaatatg 2100

 taactgggtt gattttaagt aaaattattt gtgtattgat aaaagtctaa 2150

 tttcttatca tgtgttttga attttttctt ttaataaaaa atgaccattg 2200

 aagcagtgaa aaaaaaaaaa aaaaa 2225

<210> 6061
<211> 314
<212> PRT
<213> Homo sapien

<400> 6061
 Met Lys Asp Ser Glu Lys His Ile Glu Val Glu Val Arg Lys Phe
   1               5                  10                  15

 Leu Ala Leu Lys Gln Thr Pro Asp Phe His Thr Val Ile Gly Asp
                  20                  25                  30

 Thr Val Thr Gly Leu Leu Glu Arg Cys Lys Ala Glu Pro Ser Phe
                  35                  40                  45

 Tyr Pro Arg Asn Cys Leu Met Gln Leu Ile Gln Thr His Val Leu
                  50                  55                  60

 Ser Tyr Ser Leu Cys Pro Asp Leu Met Glu Ile Ala Leu Lys Lys
                  65                  70                  75

 Lys Asp Val Gln Leu Leu Gln Leu Cys Leu Gln Gln Phe Pro Asp
                  80                  85                  90

 Ile Pro Glu Ser Val Thr Cys Ala Cys Leu Lys Ile Phe Leu Ser
                  95                 100                 105

 Ile Gly Asp Asp Ser Leu Gln Glu Thr Asp Val Asn Met Glu Ser
                 110                 115                 120

 Val Phe Asp Tyr Ser Ile Asn Ser Val His Asp Glu Lys Met Glu
                 125                 130                 135

 Glu Gln Thr Glu Ile Leu Gln Asn Gly Phe Asn Pro Glu Glu Asp
                 140                 145                 150

 Lys Cys Asn Asn Cys Asp Gln Glu Leu Asn Lys Lys Pro Gln Asp
                 155                 160                 165

 Glu Thr Lys Glu Ser Thr Ser Cys Pro Val Val Gln Lys Arg Ala
                 170                 175                 180

 Ala Leu Leu Asn Ala Ile Leu His Ser Ala Tyr Ser Glu Thr Phe
                 185                 190                 195

 Leu Leu Pro His Leu Lys Asp Ile Pro Ala Gln His Ile Thr Leu
                 200                 205                 210

 Phe Leu Lys Tyr Leu Tyr Phe Leu Tyr Leu Lys Cys Ser Glu Asn
                 215                 220                 225

 Ala Thr Met Thr Leu Pro Gly Ile His Pro Pro Thr Leu Asn Gln
                 230                 235                 240

 Ile Met Asp Trp Ile Cys Leu Leu Leu Asp Ala Asn Phe Thr Val
                 245                 250                 255

 Val Val Met Met Pro Glu Ala Lys Arg Leu Leu Ile Asn Leu Tyr
                 260                 265                 270

 Lys Leu Val Lys Ser Gln Ile Ser Val Tyr Ser Glu Leu Asn Lys
                 275                 280                 285

 Ile Glu Val Ser Phe Arg Glu Leu Gln Lys Leu Asn Gln Glu Lys
                 290                 295                 300

 Asn Asn Arg Gly Leu Tyr Ser Ile Glu Val Leu Glu Leu Phe
                 305                 310

<210> 6062
<211> 971
<212> DNA
<213> Homo sapien

<400> 6062
 taaaacttta ggaaattagt accagacttt tatattggtc aacagcaaaa 50

 tgaacattac tactcagcct ccaacacatg cagtttgcct ataccaggga 100

 tcctgtcaaa atatacacca cttatagctt cttaagtgca gttatcatag 150

 agcacagtcc ctgacatcac acagctgcag agatgaataa acaaagagga 200

 acctactcag aagtgagtct ggcccaggac ccaaagaggc agcaaaggaa 250

 acttaagggc aataaaatct ccatttcagg aaccaaacag gaaatattcc 300

 aagtagaatt aaaccttcaa aatgcttctt cggatcatca agggaatgac 350

 aagacatatc actgcaaagg tttactgcca cctccagaga agctcactgc 400

 tgaggtccta ggaatcattt gcattgtcct gatggccact gtgttaaaaa 450

 caatagttct tattccttgt attggagtac tggagcagaa caatttttcc 500

 ctgaatagaa gaatgcagaa agcacgtcat tgtggccatt gtcctgagga 550

 gtggattaca tattccaaca gttgttatta cattggtaag gaaagaagaa 600

 cttgggaaga aagagtttgc tggcctgtgc ttcgaagaac tctgatctgc 650

 tttctataga taatgaggaa gaaatggtaa gacgtaaatg tttcaacact 700

 ttactaaaag cttatttctg tcaatatcat atttgtagaa atcatccata 750

 tgtttataca tatatttact tcatatattt ttaagtctgt gtagtattca 800

 actgacttca taatattttt atattcatat actgttaatg cacatttggt 850

 tatttccagt tttgcttttc atggaaaccc atgcttctat aaatgttttt 900

 atcacaaaat aaatataaag aaaactaaaa aaaaaccaaa aaaaaaaaaa 950

 aaaaaggcgg ccgcgatata g 971

<210> 6063
<211> 158
<212> PRT
<213> Homo sapien

<400> 6063
 Met Asn Lys Gln Arg Gly Thr Tyr Ser Glu Val Ser Leu Ala Gln
   1               5                  10                  15

 Asp Pro Lys Arg Gln Gln Arg Lys Leu Lys Gly Asn Lys Ile Ser
                  20                  25                  30

 Ile Ser Gly Thr Lys Gln Glu Ile Phe Gln Val Glu Leu Asn Leu
                  35                  40                  45

 Gln Asn Ala Ser Ser Asp His Gln Gly Asn Asp Lys Thr Tyr His
                  50                  55                  60

 Cys Lys Gly Leu Leu Pro Pro Pro Glu Lys Leu Thr Ala Glu Val
                  65                  70                  75

 Leu Gly Ile Ile Cys Ile Val Leu Met Ala Thr Val Leu Lys Thr
                  80                  85                  90

 Ile Val Leu Ile Pro Cys Ile Gly Val Leu Glu Gln Asn Asn Phe
                  95                 100                 105

 Ser Leu Asn Arg Arg Met Gln Lys Ala Arg His Cys Gly His Cys
                 110                 115                 120

 Pro Glu Glu Trp Ile Thr Tyr Ser Asn Ser Cys Tyr Tyr Ile Gly
                 125                 130                 135

 Lys Glu Arg Arg Thr Trp Glu Glu Arg Val Cys Trp Pro Val Leu
                 140                 145                 150

 Arg Arg Thr Leu Ile Cys Phe Leu
                 155

<210> 6064
<211> 6126
<212> DNA
<213> Homo sapien

<400> 6064
 gaattcttaa cagtaaagtt ctgtaattga gacagaattc ccaaataaag 50

 tcaagagtaa aattcagata gaggagcagt tatacatcag tgggaaattt 100

 ggttggcaga aaaattacca ggtcatacaa cttaatgata gacctgaagt 150

 cttatttaaa atgattctct aaaattgaag aattggatta agggggcctt 200

 gtttggctga ttttcatact ttttcctctt agtctacagg ttggctgcat 250

 agaagaaaaa ggtagagtta tttataatct tgtaaatctt ggactttgag 300

 tcatctattt tcttttacag tcatcgaata cttttggaaa taaggtaata 350

 tatgcctttt gagctgtctt gacgttcaca gatataaaat attaaatata 400

 ttttaatttt gtgcccttgc agattgatca cttattcatt agtaatttac 450

 cagagattgt ggtggagtta ttgatgacgt tacatgagcc agcaaattct 500

 agtgccagtc agagcactga cctctgtgac ttttcagggg atttggatcc 550

 tgctcctaat ccacctcatt ttccatcgca tgtgattaaa gcaacatttg 600

 cctatatcag caattgtcat aaaaccaagt taaaaagcat tttagaaatt 650

 ctttccaaaa gccctgattc ctatcagaaa attcttcttg ccatatgtga 700

 gcaagcagct gaaacaaata atgtttataa gaagcacaga attcttaaaa 750

 tatatcacct gtttgttagt ttattactga aagatataaa aagtggctta 800

 ggaggagctt gggcctttgt tcttcgagac gttatttata ctttgattca 850

 ctatatcaac caaaggcctt cttgtatcat ggatgtgtca ttacgtagct 900

 tctccctttg ttgtgactta ttaagtcagg tttgccagac agccgtgact 950

 tactgtaagg atgctctaga aaaccatctt catgttattg ttggtacact 1000

 tatacccctt gtgtatgagc aggtggaggt tcagaaacag gtattggact 1050

 tgttgaaata cttagtgata gataacaagg ataatgaaaa cctctatatc 1100

 acgattaagc ttttagatcc ttttcctgac catgttgttt ttaaggattt 1150

 gcgtattact cagcaaaaaa tcaaatacag tagaggaccc ttttcactct 1200

 tggaggaaat taaccatttt ctctcagtaa gtgtttatga tgcacttcca 1250

 ttgacaagac ttgaaggact aaaggatctt cgaagacaac tggaactaca 1300

 taaagatcag atggtggaca ttatgagagc ttctcaggat aatccgcaag 1350

 atgggattat ggtgaaacta gttgtcaatt tgttgcagtt atccaagatg 1400

 gcaataaacc acactggtga aaaagaagtt ctagaggctg ttggaagctg 1450

 cttgggagaa gtgggtccta tagatttctc taccatagct atacaacata 1500

 gtaaagatgc atcttatacc aaggccctta agttatttga agataaagaa 1550

 cttcagtgga ccttcataat gctgacctac ctgaataaca cactggtaga 1600

 agattgtgtc aaagttcgat cagcagctgt tacctgtttg aaaaacattt 1650

 tagccacaaa gactggacat agtttctggg agatttataa gatgacaaca 1700

 gatccaatgc tggcctatct acagcctttt agaacatcaa gaaaaaagtt 1750

 tttagaagta cccagatttg acaaagaaaa cccttttgaa ggcctggatg 1800

 atataaatct gtggattcct ctaagtgaaa atcatgacat ttggataaag 1850

 acactgactt gtgctttttt ggacagtgga ggcacaaaat gtgaaattct 1900

 tcaattatta aagccaatgt gtgaagtgaa aactgacttt tgtcagactg 1950

 tacttccata cttgattcat gatattttac tccaagatac aaatgaatca 2000

 tggagaaatc tgctttctac acatgttcag ggatttttca ccagctgtct 2050

 tcgacacttc tcgcaaacga gccgatccac aacccctgca aacttggatt 2100

 cagagtcaga gcactttttc cgatgctgtt tggataaaaa atcacaaaga 2150

 acaatgcttg ctgttgtgga ctacatgaga agacaaaaga gaccttcttc 2200

 aggaacaatt tttaatgatg ctttctggct ggatttaaat tatctagaag 2250

 ttgccaaggt agctcagtct tgtgctgctc actttacagc tttactctat 2300

 gcagaaatct atgcagataa gaaaagtatg gatgatcaag agaaaagaag 2350

 tcttgcattt gaagaaggaa gccagagtac aactatttct agcttgagtg 2400

 aaaaaagtaa agaagaaact ggaataagtt tacaggatct tctcttagaa 2450

 atctacagaa gtatagggga gccagatagt ttgtatggct gtggtggagg 2500

 gaagatgtta caacccatta ctagactacg aacatatgaa cacgaagcaa 2550

 tgtggggcaa agccctagta acatatgacc tcgaaacagc aatcccctca 2600

 tcaacacgcc aggcaggaat cattcaggcc ttgcagaatt tgggactctg 2650

 ccatattctt tccgtctatt taaaaggatt ggattatgaa aataaagact 2700

 ggtgtcctga actagaagaa cttcattacc aagcagcatg gaggaatatg 2750

 cagtgggacc attgcacttc cgtcagcaaa gaagtagaag gaaccagtta 2800

 ccatgaatca ttgtacaatg ctctacaatc tctaagagac agagaattct 2850

 ctacatttta tgaaagtctc aaatatgcca gagtaaaaga agtggaagag 2900

 atgtgtaagc gcagccttga gtctgtgtat tcgctctatc ccacacttag 2950

 caggttgcag gccattggag agctggaaag cattggggag cttttctcaa 3000

 gatcagtcac acatagacaa ctctctgaag tatatattaa gtggcagaaa 3050

 cactcccagc ttctcaagga cagtgatttt agttttcagg agcctatcat 3100

 ggctctacgc acagtcattt tggagatcct gatggaaaag gaaatggaca 3150

 actcacaaag agaatgtatt aaggacattc tcaccaaaca ccttgtagaa 3200

 ctctctatac tggccagaac tttcaagaac actcagctcc ctgaaagggc 3250

 aatatttcaa attaaacagt acaattcagt tagctgtgga gtctctgagt 3300

 ggcagctgga agaagcacaa gtattctggg caaaaaagga gcagagtctt 3350

 gccctgagta ttctcaagca aatgatcaag aagttggatg ccagctgtgc 3400

 agcgaacaat cccagcctaa aacttacata cacagaatgt ctgagggttt 3450

 gtggcaactg gttagcagaa acgtgcttag aaaatcctgc ggtcatcatg 3500

 cagacctatc tagaaaaggc agtagaagtt gctggaaatt atgatggaga 3550

 aagtagtgat gagctaagaa atggaaaaat gaaggcattt ctctcattag 3600

 cccggttttc agatactcaa taccaaagaa ttgaaaacta catgaaatca 3650

 tcggaatttg aaaacaagca agctctcctg aaaagagcca aagaggaagt 3700

 aggtctcctt agggaacata aaattcagac aaacagatac acagtaaagg 3750

 ttcagcgaga gctggagttg gatgaattag ccctgcgtgc actgaaagag 3800

 gatcgtaaac gcttcttatg taaagcagtt gaaaattata tcaactgctt 3850

 attaagtgga gaagaacatg atatgtgggt attccgactt tgttccctct 3900

 ggcttgaaaa ttctggagtt tctgaagtca atggcatgat gaagagagac 3950

 ggaatgaaga ttccaacata taaatttttg cctcttatgt accaattggc 4000

 tgctagaatg gggaccaaga tgatgggagg cctaggattt catgaagtcc 4050

 tcaataatct aatctctaga atttcaatgg atcaccccca tcacactttg 4100

 tttattatac tggccttagc aaatgcaaac agagatgaat ttctgactaa 4150

 accagaggta gccagaagaa gcagaataac taaaaatgtg cctaaacaaa 4200

 gctctcagct tgatgaggat cgaacagagg ctgcaaatag aataatatgt 4250

 actatcagaa gtaggagacc tcagatggtc agaagtgttg aggcactttg 4300

 tgatgcttat attatattag caaacttaga tgccactcag tggaagactc 4350

 agagaaaagg cataaatatt ccagcagacc agccaattac taaacttaag 4400

 aatttagaag atgttgttgt ccctactatg gaaattaagg tggaccacac 4450

 aggagaatat ggaaatctgg tgactataca gtcatttaaa gcagaatttc 4500

 gcttagcagg aggtgtaaat ttaccaaaaa taatagattg tgtaggttcc 4550

 gatggcaagg agaggagaca gcttgttaag ggccgtgatg acctgagaca 4600

 agatgctgtc atgcaacagg tcttccagat gtgtaataca ttactgcaga 4650

 gaaacacgga aactaggaag aggaaattaa ctatctgtac ttataaggtg 4700

 gttcccctct ctcagcgaag tggtgttctt gaatggtgca caggaactgt 4750

 ccccattggt gaatttcttg ttaacaatga agatggtgct cataaaagat 4800

 acaggccaaa tgatttcagt gcctttcagt gccaaaagaa aatgatggag 4850

 gtgcaaaaaa agtcttttga agagaaatat gaagtcttca tggatgtttg 4900

 ccaaaatttt caaccagttt tccgttactt ctgcatggaa aaattcttgg 4950

 atccagctat ttggtttgag aagcgattgg cttatacgcg cagtgtagct 5000

 acttcttcta ttgttggtta catacttgga cttggtgata gacatgtaca 5050

 gaatatcttg ataaatgagc agtcagcaga acttgtacat atagatctag 5100

 gtgttgcttt tgaacagggc aaaatccttc ctactcctga gacagttcct 5150

 tttagactca ccagagatat tgtggatggc atgggcatta cgggtgttga 5200

 aggtgtcttc agaagatgct gtgagaaaac catggaagtg atgagaaact 5250

 ctcaggaaac tctgttaacc attgtagagg tccttctata tgatccactc 5300

 tttgactgga ccatgaatcc tttgaaagct ttgtatttac agcagaggcc 5350

 ggaagatgaa actgagcttc accctactct gaatgcagat gaccaagaat 5400

 gcaaacgaaa tctcagtgat attgaccaga gtttcaacaa agtagctgaa 5450

 cgtgtcttaa tgagactaca agagaaactg aaaggagtgg aagaaggcac 5500

 tgtgctcagt gttggtggac aagtgaattt gctcatacag caggccatag 5550

 accccaaaaa tctcagccga cttttcccag gatggaaagc ttgggtgtga 5600

 tcttcagtat atgaattacc ctttcattca gcctttagaa attatatttt 5650

 agcctttatt tttaacctgc caacatactt taagtaggga ttaatattta 5700

 agtgaactat tgtgggtttt tttgaatgtt ggttttaata cttgatttaa 5750

 tcaccactca aaaatgtttt gatggtctta aggaacatct ctgctttcac 5800

 tctttagaaa taatggtcat tcgggctggg cgcagcggct cacgcctgta 5850

 atcccagcac tttgggaggc cgaggtgagc ggatcacaag gtcaggagtt 5900

 cgagaccagc ctggccaaga gaccagcctg gccagtatgg tgaaaccctg 5950

 tctctactaa aaatacaaaa attagccgag catggtggcg ggcacctgta 6000

 atcccagcta ctcgagaggc tgaggcagga gaatctcttg aacctgggag 6050

 gtgaaggttg ctgtgggcca aaatcatgcc attgcactcc agcctgggtg 6100

 acaagagcga aactccatct caaaaa 6126

<210> 6065
<211> 1708
<212> PRT
<213> Homo sapien

<400> 6065
 Met Thr Leu His Glu Pro Ala Asn Ser Ser Ala Ser Gln Ser Thr
   1               5                  10                  15

 Asp Leu Cys Asp Phe Ser Gly Asp Leu Asp Pro Ala Pro Asn Pro
                  20                  25                  30

 Pro His Phe Pro Ser His Val Ile Lys Ala Thr Phe Ala Tyr Ile
                  35                  40                  45

 Ser Asn Cys His Lys Thr Lys Leu Lys Ser Ile Leu Glu Ile Leu
                  50                  55                  60

 Ser Lys Ser Pro Asp Ser Tyr Gln Lys Ile Leu Leu Ala Ile Cys
                  65                  70                  75

 Glu Gln Ala Ala Glu Thr Asn Asn Val Tyr Lys Lys His Arg Ile
                  80                  85                  90

 Leu Lys Ile Tyr His Leu Phe Val Ser Leu Leu Leu Lys Asp Ile
                  95                 100                 105

 Lys Ser Gly Leu Gly Gly Ala Trp Ala Phe Val Leu Arg Asp Val
                 110                 115                 120

 Ile Tyr Thr Leu Ile His Tyr Ile Asn Gln Arg Pro Ser Cys Ile
                 125                 130                 135

 Met Asp Val Ser Leu Arg Ser Phe Ser Leu Cys Cys Asp Leu Leu
                 140                 145                 150

 Ser Gln Val Cys Gln Thr Ala Val Thr Tyr Cys Lys Asp Ala Leu
                 155                 160                 165

 Glu Asn His Leu His Val Ile Val Gly Thr Leu Ile Pro Leu Val
                 170                 175                 180

 Tyr Glu Gln Val Glu Val Gln Lys Gln Val Leu Asp Leu Leu Lys
                 185                 190                 195

 Tyr Leu Val Ile Asp Asn Lys Asp Asn Glu Asn Leu Tyr Ile Thr
                 200                 205                 210

 Ile Lys Leu Leu Asp Pro Phe Pro Asp His Val Val Phe Lys Asp
                 215                 220                 225

 Leu Arg Ile Thr Gln Gln Lys Ile Lys Tyr Ser Arg Gly Pro Phe
                 230                 235                 240

 Ser Leu Leu Glu Glu Ile Asn His Phe Leu Ser Val Ser Val Tyr
                 245                 250                 255

 Asp Ala Leu Pro Leu Thr Arg Leu Glu Gly Leu Lys Asp Leu Arg
                 260                 265                 270

 Arg Gln Leu Glu Leu His Lys Asp Gln Met Val Asp Ile Met Arg
                 275                 280                 285

 Ala Ser Gln Asp Asn Pro Gln Asp Gly Ile Met Val Lys Leu Val
                 290                 295                 300

 Val Asn Leu Leu Gln Leu Ser Lys Met Ala Ile Asn His Thr Gly
                 305                 310                 315

 Glu Lys Glu Val Leu Glu Ala Val Gly Ser Cys Leu Gly Glu Val
                 320                 325                 330

 Gly Pro Ile Asp Phe Ser Thr Ile Ala Ile Gln His Ser Lys Asp
                 335                 340                 345

 Ala Ser Tyr Thr Lys Ala Leu Lys Leu Phe Glu Asp Lys Glu Leu
                 350                 355                 360

 Gln Trp Thr Phe Ile Met Leu Thr Tyr Leu Asn Asn Thr Leu Val
                 365                 370                 375

 Glu Asp Cys Val Lys Val Arg Ser Ala Ala Val Thr Cys Leu Lys
                 380                 385                 390

 Asn Ile Leu Ala Thr Lys Thr Gly His Ser Phe Trp Glu Ile Tyr
                 395                 400                 405

 Lys Met Thr Thr Asp Pro Met Leu Ala Tyr Leu Gln Pro Phe Arg
                 410                 415                 420

 Thr Ser Arg Lys Lys Phe Leu Glu Val Pro Arg Phe Asp Lys Glu
                 425                 430                 435

 Asn Pro Phe Glu Gly Leu Asp Asp Ile Asn Leu Trp Ile Pro Leu
                 440                 445                 450

 Ser Glu Asn His Asp Ile Trp Ile Lys Thr Leu Thr Cys Ala Phe
                 455                 460                 465

 Leu Asp Ser Gly Gly Thr Lys Cys Glu Ile Leu Gln Leu Leu Lys
                 470                 475                 480

 Pro Met Cys Glu Val Lys Thr Asp Phe Cys Gln Thr Val Leu Pro
                 485                 490                 495

 Tyr Leu Ile His Asp Ile Leu Leu Gln Asp Thr Asn Glu Ser Trp
                 500                 505                 510

 Arg Asn Leu Leu Ser Thr His Val Gln Gly Phe Phe Thr Ser Cys
                 515                 520                 525

 Leu Arg His Phe Ser Gln Thr Ser Arg Ser Thr Thr Pro Ala Asn
                 530                 535                 540

 Leu Asp Ser Glu Ser Glu His Phe Phe Arg Cys Cys Leu Asp Lys
                 545                 550                 555

 Lys Ser Gln Arg Thr Met Leu Ala Val Val Asp Tyr Met Arg Arg
                 560                 565                 570

 Gln Lys Arg Pro Ser Ser Gly Thr Ile Phe Asn Asp Ala Phe Trp
                 575                 580                 585

 Leu Asp Leu Asn Tyr Leu Glu Val Ala Lys Val Ala Gln Ser Cys
                 590                 595                 600

 Ala Ala His Phe Thr Ala Leu Leu Tyr Ala Glu Ile Tyr Ala Asp
                 605                 610                 615

 Lys Lys Ser Met Asp Asp Gln Glu Lys Arg Ser Leu Ala Phe Glu
                 620                 625                 630

 Glu Gly Ser Gln Ser Thr Thr Ile Ser Ser Leu Ser Glu Lys Ser
                 635                 640                 645

 Lys Glu Glu Thr Gly Ile Ser Leu Gln Asp Leu Leu Leu Glu Ile
                 650                 655                 660

 Tyr Arg Ser Ile Gly Glu Pro Asp Ser Leu Tyr Gly Cys Gly Gly
                 665                 670                 675

 Gly Lys Met Leu Gln Pro Ile Thr Arg Leu Arg Thr Tyr Glu His
                 680                 685                 690

 Glu Ala Met Trp Gly Lys Ala Leu Val Thr Tyr Asp Leu Glu Thr
                 695                 700                 705

 Ala Ile Pro Ser Ser Thr Arg Gln Ala Gly Ile Ile Gln Ala Leu
                 710                 715                 720

 Gln Asn Leu Gly Leu Cys His Ile Leu Ser Val Tyr Leu Lys Gly
                 725                 730                 735

 Leu Asp Tyr Glu Asn Lys Asp Trp Cys Pro Glu Leu Glu Glu Leu
                 740                 745                 750

 His Tyr Gln Ala Ala Trp Arg Asn Met Gln Trp Asp His Cys Thr
                 755                 760                 765

 Ser Val Ser Lys Glu Val Glu Gly Thr Ser Tyr His Glu Ser Leu
                 770                 775                 780

 Tyr Asn Ala Leu Gln Ser Leu Arg Asp Arg Glu Phe Ser Thr Phe
                 785                 790                 795

 Tyr Glu Ser Leu Lys Tyr Ala Arg Val Lys Glu Val Glu Glu Met
                 800                 805                 810

 Cys Lys Arg Ser Leu Glu Ser Val Tyr Ser Leu Tyr Pro Thr Leu
                 815                 820                 825

 Ser Arg Leu Gln Ala Ile Gly Glu Leu Glu Ser Ile Gly Glu Leu
                 830                 835                 840

 Phe Ser Arg Ser Val Thr His Arg Gln Leu Ser Glu Val Tyr Ile
                 845                 850                 855

 Lys Trp Gln Lys His Ser Gln Leu Leu Lys Asp Ser Asp Phe Ser
                 860                 865                 870

 Phe Gln Glu Pro Ile Met Ala Leu Arg Thr Val Ile Leu Glu Ile
                 875                 880                 885

 Leu Met Glu Lys Glu Met Asp Asn Ser Gln Arg Glu Cys Ile Lys
                 890                 895                 900

 Asp Ile Leu Thr Lys His Leu Val Glu Leu Ser Ile Leu Ala Arg
                 905                 910                 915

 Thr Phe Lys Asn Thr Gln Leu Pro Glu Arg Ala Ile Phe Gln Ile
                 920                 925                 930

 Lys Gln Tyr Asn Ser Val Ser Cys Gly Val Ser Glu Trp Gln Leu
                 935                 940                 945

 Glu Glu Ala Gln Val Phe Trp Ala Lys Lys Glu Gln Ser Leu Ala
                 950                 955                 960

 Leu Ser Ile Leu Lys Gln Met Ile Lys Lys Leu Asp Ala Ser Cys
                 965                 970                 975

 Ala Ala Asn Asn Pro Ser Leu Lys Leu Thr Tyr Thr Glu Cys Leu
                 980                 985                 990

 Arg Val Cys Gly Asn Trp Leu Ala Glu Thr Cys Leu Glu Asn Pro
                 995                1000                1005

 Ala Val Ile Met Gln Thr Tyr Leu Glu Lys Ala Val Glu Val Ala
                1010                1015                1020

 Gly Asn Tyr Asp Gly Glu Ser Ser Asp Glu Leu Arg Asn Gly Lys
                1025                1030                1035

 Met Lys Ala Phe Leu Ser Leu Ala Arg Phe Ser Asp Thr Gln Tyr
                1040                1045                1050

 Gln Arg Ile Glu Asn Tyr Met Lys Ser Ser Glu Phe Glu Asn Lys
                1055                1060                1065

 Gln Ala Leu Leu Lys Arg Ala Lys Glu Glu Val Gly Leu Leu Arg
                1070                1075                1080

 Glu His Lys Ile Gln Thr Asn Arg Tyr Thr Val Lys Val Gln Arg
                1085                1090                1095

 Glu Leu Glu Leu Asp Glu Leu Ala Leu Arg Ala Leu Lys Glu Asp
                1100                1105                1110

 Arg Lys Arg Phe Leu Cys Lys Ala Val Glu Asn Tyr Ile Asn Cys
                1115                1120                1125

 Leu Leu Ser Gly Glu Glu His Asp Met Trp Val Phe Arg Leu Cys
                1130                1135                1140

 Ser Leu Trp Leu Glu Asn Ser Gly Val Ser Glu Val Asn Gly Met
                1145                1150                1155

 Met Lys Arg Asp Gly Met Lys Ile Pro Thr Tyr Lys Phe Leu Pro
                1160                1165                1170

 Leu Met Tyr Gln Leu Ala Ala Arg Met Gly Thr Lys Met Met Gly
                1175                1180                1185

 Gly Leu Gly Phe His Glu Val Leu Asn Asn Leu Ile Ser Arg Ile
                1190                1195                1200

 Ser Met Asp His Pro His His Thr Leu Phe Ile Ile Leu Ala Leu
                1205                1210                1215

 Ala Asn Ala Asn Arg Asp Glu Phe Leu Thr Lys Pro Glu Val Ala
                1220                1225                1230

 Arg Arg Ser Arg Ile Thr Lys Asn Val Pro Lys Gln Ser Ser Gln
                1235                1240                1245

 Leu Asp Glu Asp Arg Thr Glu Ala Ala Asn Arg Ile Ile Cys Thr
                1250                1255                1260

 Ile Arg Ser Arg Arg Pro Gln Met Val Arg Ser Val Glu Ala Leu
                1265                1270                1275

 Cys Asp Ala Tyr Ile Ile Leu Ala Asn Leu Asp Ala Thr Gln Trp
                1280                1285                1290

 Lys Thr Gln Arg Lys Gly Ile Asn Ile Pro Ala Asp Gln Pro Ile
                1295                1300                1305

 Thr Lys Leu Lys Asn Leu Glu Asp Val Val Val Pro Thr Met Glu
                1310                1315                1320

 Ile Lys Val Asp His Thr Gly Glu Tyr Gly Asn Leu Val Thr Ile
                1325                1330                1335

 Gln Ser Phe Lys Ala Glu Phe Arg Leu Ala Gly Gly Val Asn Leu
                1340                1345                1350

 Pro Lys Ile Ile Asp Cys Val Gly Ser Asp Gly Lys Glu Arg Arg
                1355                1360                1365

 Gln Leu Val Lys Gly Arg Asp Asp Leu Arg Gln Asp Ala Val Met
                1370                1375                1380

 Gln Gln Val Phe Gln Met Cys Asn Thr Leu Leu Gln Arg Asn Thr
                1385                1390                1395

 Glu Thr Arg Lys Arg Lys Leu Thr Ile Cys Thr Tyr Lys Val Val
                1400                1405                1410

 Pro Leu Ser Gln Arg Ser Gly Val Leu Glu Trp Cys Thr Gly Thr
                1415                1420                1425

 Val Pro Ile Gly Glu Phe Leu Val Asn Asn Glu Asp Gly Ala His
                1430                1435                1440

 Lys Arg Tyr Arg Pro Asn Asp Phe Ser Ala Phe Gln Cys Gln Lys
                1445                1450                1455

 Lys Met Met Glu Val Gln Lys Lys Ser Phe Glu Glu Lys Tyr Glu
                1460                1465                1470

 Val Phe Met Asp Val Cys Gln Asn Phe Gln Pro Val Phe Arg Tyr
                1475                1480                1485

 Phe Cys Met Glu Lys Phe Leu Asp Pro Ala Ile Trp Phe Glu Lys
                1490                1495                1500

 Arg Leu Ala Tyr Thr Arg Ser Val Ala Thr Ser Ser Ile Val Gly
                1505                1510                1515

 Tyr Ile Leu Gly Leu Gly Asp Arg His Val Gln Asn Ile Leu Ile
                1520                1525                1530

 Asn Glu Gln Ser Ala Glu Leu Val His Ile Asp Leu Gly Val Ala
                1535                1540                1545

 Phe Glu Gln Gly Lys Ile Leu Pro Thr Pro Glu Thr Val Pro Phe
                1550                1555                1560

 Arg Leu Thr Arg Asp Ile Val Asp Gly Met Gly Ile Thr Gly Val
                1565                1570                1575

 Glu Gly Val Phe Arg Arg Cys Cys Glu Lys Thr Met Glu Val Met
                1580                1585                1590

 Arg Asn Ser Gln Glu Thr Leu Leu Thr Ile Val Glu Val Leu Leu
                1595                1600                1605

 Tyr Asp Pro Leu Phe Asp Trp Thr Met Asn Pro Leu Lys Ala Leu
                1610                1615                1620

 Tyr Leu Gln Gln Arg Pro Glu Asp Glu Thr Glu Leu His Pro Thr
                1625                1630                1635

 Leu Asn Ala Asp Asp Gln Glu Cys Lys Arg Asn Leu Ser Asp Ile
                1640                1645                1650

 Asp Gln Ser Phe Asn Lys Val Ala Glu Arg Val Leu Met Arg Leu
                1655                1660                1665

 Gln Glu Lys Leu Lys Gly Val Glu Glu Gly Thr Val Leu Ser Val
                1670                1675                1680

 Gly Gly Gln Val Asn Leu Leu Ile Gln Gln Ala Ile Asp Pro Lys
                1685                1690                1695

 Asn Leu Ser Arg Leu Phe Pro Gly Trp Lys Ala Trp Val
                1700                1705

<210> 6066
<211> 1700
<212> DNA
<213> Homo sapien

<400> 6066
 ggcggcggca gcgggttcgg ttgcgcgtgg cgcacggggt gggagcggag 50

 cccaggccgg gagcaggcgc cgccgccagc gaccatgggg aacgtgttgg 100

 ctgccagctc gccgcccgca gggccgccac cgccgcctgc gccggccctc 150

 gtggggctgc cgccacctcc gccctcgccg ccgggcttca cgctgccgcc 200

 gctgggaggc agcctgggcg ccggcaccag tacgagtcga agttcggaac 250

 ggacccccgg ggctgcaacc gccagcgcct caggggccgc cgaggatggg 300

 gcctgcggct gcctgcccaa cccgggcaca ttcgaggagt gccaccggaa 350

 gtgcaaggag ctgtttccca ttcagatgga gggtgtcaag ctcacagtca 400

 acaaagggtt gagtaaccat tttcaggtca accacacagt agccctcagc 450

 acaatcgggg agtccaacta ccacttcggg gtcacatatg tggggacaaa 500

 gcagctgagt cccacagagg cgttccctgt actggtgggt gacatggaca 550

 acagtggcag tctcaacgct caggtcattc accagctggg ccccggtctc 600

 aggtccaaga tggccatcca gacccagcag tcgaagtttg tgaactggca 650

 ggtggacggg gagtatcggg gctctgactt cacagcagcc gtcaccctgg 700

 ggaacccaga cgtcctcgtg ggttcaggaa tcctcgtagc ccactacctc 750

 cagagcatca cgccttgcct ggccctgggt ggagagctgg tctaccaccg 800

 gcggcctgga gaggagggca ctgtcatgtc tctagctggg aaatacacat 850

 tgaacaactg gttggcaacg gtaacgttgg gccaggcggg catgcacgca 900

 acatactacc acaaagccag tgaccagctg caggtgggtg tggagtttga 950

 ggccagcaca aggatgcagg acaccagcgt ctccttcggg taccagctgg 1000

 acctgcccaa ggccaacctc ctcttcaaag gctctgtgga tagcaactgg 1050

 atcgtgggtg ccacgctgga gaagaagctc ccacccctgc ccctgacact 1100

 ggcccttggg gccttcctga atcaccgcaa gaacaagttt cagtgtggct 1150

 ttggcctcac catcggctga gccctcctgg cccccgcctt ccacgccctt 1200

 ccgattccac ctccacctcc acctccccct gccacagagg ggagacctga 1250

 gcccccctcc cttccctccc cccttggggg tcgggggggg acattggaaa 1300

 ggagggaccc cgccacccca gcagctgagg aggggattct ggaactgaat 1350

 ggcgcttcgg gattctgagt agcaggggca gcatgcccag tgggcctggg 1400

 gtcccgggag ggattccgga attgaggggc acgcaggatt ctgagcacca 1450

 ggggcagagg cggccagaca acctcaggga ggagtgtcct ggcgtcccca 1500

 tcctccaaag ggcctgggcc cgccccgagg gggcagcgag aggagcttcc 1550

 ccatccccgg tcagtccacc ctgccccgtc cactttccca tctcctcggt 1600

 ataaatcatg tttataagtt atggaagaac cgggacattt tacagaaaaa 1650

 aaacaaaaaa caacaaaaaa tatacgtggg aaaaaaaaaa aaaaaaaaaa 1700

<210> 6067
<211> 361
<212> PRT
<213> Homo sapien

<400> 6067
 Met Gly Asn Val Leu Ala Ala Ser Ser Pro Pro Ala Gly Pro Pro
   1               5                  10                  15

 Pro Pro Pro Ala Pro Ala Leu Val Gly Leu Pro Pro Pro Pro Pro
                  20                  25                  30

 Ser Pro Pro Gly Phe Thr Leu Pro Pro Leu Gly Gly Ser Leu Gly
                  35                  40                  45

 Ala Gly Thr Ser Thr Ser Arg Ser Ser Glu Arg Thr Pro Gly Ala
                  50                  55                  60

 Ala Thr Ala Ser Ala Ser Gly Ala Ala Glu Asp Gly Ala Cys Gly
                  65                  70                  75

 Cys Leu Pro Asn Pro Gly Thr Phe Glu Glu Cys His Arg Lys Cys
                  80                  85                  90

 Lys Glu Leu Phe Pro Ile Gln Met Glu Gly Val Lys Leu Thr Val
                  95                 100                 105

 Asn Lys Gly Leu Ser Asn His Phe Gln Val Asn His Thr Val Ala
                 110                 115                 120

 Leu Ser Thr Ile Gly Glu Ser Asn Tyr His Phe Gly Val Thr Tyr
                 125                 130                 135

 Val Gly Thr Lys Gln Leu Ser Pro Thr Glu Ala Phe Pro Val Leu
                 140                 145                 150

 Val Gly Asp Met Asp Asn Ser Gly Ser Leu Asn Ala Gln Val Ile
                 155                 160                 165

 His Gln Leu Gly Pro Gly Leu Arg Ser Lys Met Ala Ile Gln Thr
                 170                 175                 180

 Gln Gln Ser Lys Phe Val Asn Trp Gln Val Asp Gly Glu Tyr Arg
                 185                 190                 195

 Gly Ser Asp Phe Thr Ala Ala Val Thr Leu Gly Asn Pro Asp Val
                 200                 205                 210

 Leu Val Gly Ser Gly Ile Leu Val Ala His Tyr Leu Gln Ser Ile
                 215                 220                 225

 Thr Pro Cys Leu Ala Leu Gly Gly Glu Leu Val Tyr His Arg Arg
                 230                 235                 240

 Pro Gly Glu Glu Gly Thr Val Met Ser Leu Ala Gly Lys Tyr Thr
                 245                 250                 255

 Leu Asn Asn Trp Leu Ala Thr Val Thr Leu Gly Gln Ala Gly Met
                 260                 265                 270

 His Ala Thr Tyr Tyr His Lys Ala Ser Asp Gln Leu Gln Val Gly
                 275                 280                 285

 Val Glu Phe Glu Ala Ser Thr Arg Met Gln Asp Thr Ser Val Ser
                 290                 295                 300

 Phe Gly Tyr Gln Leu Asp Leu Pro Lys Ala Asn Leu Leu Phe Lys
                 305                 310                 315

 Gly Ser Val Asp Ser Asn Trp Ile Val Gly Ala Thr Leu Glu Lys
                 320                 325                 330

 Lys Leu Pro Pro Leu Pro Leu Thr Leu Ala Leu Gly Ala Phe Leu
                 335                 340                 345

 Asn His Arg Lys Asn Lys Phe Gln Cys Gly Phe Gly Leu Thr Ile
                 350                 355                 360

 Gly


<210> 6068
<211> 4166
<212> DNA
<213> Homo sapien

<400> 6068
 cggcgcgggt gttgagagcg gtgtggtagg tgttgtagcc gctatggtga 50

 agttcgcttt gtagcggccc cggctagaga gttggcctgt tccctgcctt 100

 tgtgacccgg aggagctttt gggggtgcgt caagcccctg gcctgaggca 150

 gcgaactggt ttgtggcctg tttgattcct gtcagaggtt tgctgaccca 200

 agacagtatc gaaaatgcat attaagtcaa ttattctaga gggattcaag 250

 tcctatgctc agaggaccga agtcaatggt tttgaccccc tcttcaatgc 300

 tatcactggc ttaaatggta gtgggaaatc caacatattg gactccatct 350

 gctttttact gggcatctcc aacctgtctc aggttcgggc ttctaattta 400

 caagatttag tttacaaaaa tgggcaggct ggtattacca aagcctctgt 450

 gtcaatcact tttgataatt ctgacaaaaa gcaaagtcct ttaggatttg 500

 aggttcatga tgaaatcaca gtaacaaggc aggtggttat tggtggtaga 550

 aataaatatt taatcaatgg agtcaatgcc aacaacacca gagtacagga 600

 tctcttctgt tctgttggcc ttaatgttaa caaccctcac tttctcatca 650

 tgcagggccg aattacaaaa gtattgaata tgaaaccacc agagatttta 700

 tccatgatag aagaagcagc tggaaccagg atgtatgaat acaaaaaaat 750

 agctgcacag aaaactatag aaaaaaagga ggctaagctg aaagaaatta 800

 agacgatact tgaagaagag attactccaa ccattcaaaa attaaaagag 850

 gaaagatcgt cctacttgga gtaccaaaaa gtaatgagag aaatagaaca 900

 tttgagtcgt ttatatattg cttatcagtt tttgctggct gaagatacca 950

 aagtacgctc agctgaggaa ttaaaagaaa tgcaagataa agttataaag 1000

 cttcaggaag aattgtctga gaatgataaa aaaataaaag cacttaatca 1050

 tgaaatagaa gaattggaaa aaagaaaaga taaggaaact ggagttatac 1100

 ttcgatcttt agaagatgct cttgcagagg ctcagcgagt taatactaaa 1150

 tctcaaagcg catttgatct caagaagaaa aatctggcat gtgaggaaag 1200

 caaacgcaaa gagctggaaa aaaatatggt tgaggactca aaaactttag 1250

 cagcaaagga aaaagaggtt aaaaagataa cagatggact gcatgccctt 1300

 caagaagcaa gtaataaaga tgctgaagct ctggcagctg cacagcagca 1350

 cttcaatgct gtttccgctg gcctgtccag taatgaagat ggagcagaag 1400

 caactcttgc tggtcaaatg atggcctgta aaaatgatat aagtaaagct 1450

 cagacagaag ccaaacaggc tcagatgaag ttgaagcatg ctcaacagga 1500

 attaaagaat aaacaagctg aagttaagaa gatggatagt ggctacagga 1550

 aggatcaaga agctctagaa gctgtaaaaa gacttaaaga aaaacttgaa 1600

 gctgaaatga aaaagctaaa ttatgaagaa aataaagagg aaagcctttt 1650

 ggaaaagcgc aggcagctgt ctcgtgatat tggtagattg aaagaaacat 1700

 atgaagctct attagccaga tttcccaatc ttcgatttgc atacaaggat 1750

 ccagagaaga actggaatag aaattgtgtg aaaggacttg tggcttctct 1800

 gattagtgtg aaagacactt ctgcaaccac agctttagaa ttagtggctg 1850

 gagaacgact ctacaatgtt gtagtagaca cagaagttac tggtaaaaag 1900

 ctactagaaa ggggggaact gaaacgtcga tacactataa ttccactcaa 1950

 taaaatttca gccagatgta ttgcaccaga aactctgaga gttgctcaga 2000

 atcttgttgg ccctgacaac gttcatgtgg ctctttcctt ggttgaatat 2050

 aaaccagaac ttcagaaagc aatggagttt gtctttggaa caacatttgt 2100

 ttgtgacaat atggataatg ccaaaaaagt ggcctttgat aagaggataa 2150

 tgactagaac tgtaactctc ggaggtgatg tgtttgatcc tcatgggaca 2200

 ttgagtggag gtgctcgatc ccaggcagct tccattttaa ccaagtttca 2250

 agaactcaaa gatgttcagg atgaactgag aatcaaagag aatgagctgc 2300

 gggctctaga agaggaatta gcaggtctta aaaacactgc tgaaaagtat 2350

 cgccaactaa aacagcagtg ggagatgaaa actgaagagg cagatttatt 2400

 acaaaccaag ctccagcaaa gctcatatca caagcaacaa gaagaattag 2450

 atgcccttaa aaaaaccatt gaggaaagtg aggagacttt gaaaaacact 2500

 aaagaaatcc aaagaaaagc agaagaaaaa tatgaagtat tggaaaataa 2550

 aatgaaaaat gcagaagctg aaagagagcg agaactgaaa gatgctcaga 2600

 aaaaactgga ttgtgccaaa acaaaggcag atgcatctag caagaagatg 2650

 aaagaaaaac aacaggaagt tgaagctatc actctggaac tggaagagct 2700

 caagagagag catacatctt acaaacaaca gcttgaagct gtaaatgaag 2750

 ctatcaaatc ctatgaaagt cagattgaag taatggcagc tgaggtggct 2800

 aaaaataagg agtcagtaaa taaagctcaa gaagaggtga ccaagcaaaa 2850

 agaggtgata acagcccaag acactgtaat taagctaaat atgcagaagt 2900

 ggcaaaacac aaggagcaaa acaatgattc tcagccttaa aattaaggaa 2950

 ttagaccacc acatcagcaa acataaacgg gaggctgaag atggtgctgc 3000

 aaaggtatcc aaaatgttga aagattatga ctggattaat gcagagagac 3050

 acctctttgg ccaacccaat agtgcctatg atttcaaaac taacaaccct 3100

 aaagaagctg gtcagagact tcagaagttg caagaaatga aggagaaact 3150

 aggaagaaat gtcaatatga gagctatgaa tgtattgaca gaagctgaag 3200

 agcgatgcaa tgacttgatg aagaagaaga gaattgtaga aaatgacaaa 3250

 tccaaaattc ttacaactat agaagacctt gaccagaaga aaaaccaagc 3300

 cctaaatatt gcatggcaaa aggtgaacaa ggactttggg tctatttttt 3350

 ctactctttt gcctggtgct aatgctatgc ttgcaccacc agagggtcaa 3400

 actgttttgg atggtctgga gttcaaggtt gccttaggaa atacctggaa 3450

 agaaaaccta actgaactta gtggtggtca gaggtcttta gtggccttgt 3500

 cattaatact gtccatgctt ctcttcaaac ctgctccaat ttatatcctt 3550

 gatgaggtag atgcagcctt ggatctttct catacccaaa acattggaca 3600

 gatgctgcgt actcatttca cacattctca gttcattgtg gtgtcactaa 3650

 aagaaggtat gttcaacaat gcaaacgttc ttttcaaaac caagtttgtg 3700

 gatggtgttt ctacagtagc cagatttact caatgtcaaa atggaaagat 3750

 ttcaaaggaa gcaaaatcca aggcaaaacc acccaaagga gcacatgtgg 3800

 aagtttaaac tacaaagtta tttcttcatc ttgacctgtt tttttaaatg 3850

 taaactttta aggacttgag ataactaatt tgtttatata caaaaattaa 3900

 tgttactgtg ttacttaacc catgttttct ctttatataa tcacttatcg 3950

 cttacaaatg agcatatatt cctcatctct taactagtct aattatggtc 4000

 caattattgt ggttgtgatt ttatgcatat ccatcaaaat gttttttttc 4050

 ttatgcgggt cttttatata ttagggatcc tgagataccc gattctatat 4100

 gtaaaagcta atatacaaaa aagcagatta aattacatga taaatgtagc 4150

 tgaaaaaaaa aaaaaa 4166

<210> 6069
<211> 1197
<212> PRT
<213> Homo sapien

<400> 6069
 Met His Ile Lys Ser Ile Ile Leu Glu Gly Phe Lys Ser Tyr Ala
   1               5                  10                  15

 Gln Arg Thr Glu Val Asn Gly Phe Asp Pro Leu Phe Asn Ala Ile
                  20                  25                  30

 Thr Gly Leu Asn Gly Ser Gly Lys Ser Asn Ile Leu Asp Ser Ile
                  35                  40                  45

 Cys Phe Leu Leu Gly Ile Ser Asn Leu Ser Gln Val Arg Ala Ser
                  50                  55                  60

 Asn Leu Gln Asp Leu Val Tyr Lys Asn Gly Gln Ala Gly Ile Thr
                  65                  70                  75

 Lys Ala Ser Val Ser Ile Thr Phe Asp Asn Ser Asp Lys Lys Gln
                  80                  85                  90

 Ser Pro Leu Gly Phe Glu Val His Asp Glu Ile Thr Val Thr Arg
                  95                 100                 105

 Gln Val Val Ile Gly Gly Arg Asn Lys Tyr Leu Ile Asn Gly Val
                 110                 115                 120

 Asn Ala Asn Asn Thr Arg Val Gln Asp Leu Phe Cys Ser Val Gly
                 125                 130                 135

 Leu Asn Val Asn Asn Pro His Phe Leu Ile Met Gln Gly Arg Ile
                 140                 145                 150

 Thr Lys Val Leu Asn Met Lys Pro Pro Glu Ile Leu Ser Met Ile
                 155                 160                 165

 Glu Glu Ala Ala Gly Thr Arg Met Tyr Glu Tyr Lys Lys Ile Ala
                 170                 175                 180

 Ala Gln Lys Thr Ile Glu Lys Lys Glu Ala Lys Leu Lys Glu Ile
                 185                 190                 195

 Lys Thr Ile Leu Glu Glu Glu Ile Thr Pro Thr Ile Gln Lys Leu
                 200                 205                 210

 Lys Glu Glu Arg Ser Ser Tyr Leu Glu Tyr Gln Lys Val Met Arg
                 215                 220                 225

 Glu Ile Glu His Leu Ser Arg Leu Tyr Ile Ala Tyr Gln Phe Leu
                 230                 235                 240

 Leu Ala Glu Asp Thr Lys Val Arg Ser Ala Glu Glu Leu Lys Glu
                 245                 250                 255

 Met Gln Asp Lys Val Ile Lys Leu Gln Glu Glu Leu Ser Glu Asn
                 260                 265                 270

 Asp Lys Lys Ile Lys Ala Leu Asn His Glu Ile Glu Glu Leu Glu
                 275                 280                 285

 Lys Arg Lys Asp Lys Glu Thr Gly Val Ile Leu Arg Ser Leu Glu
                 290                 295                 300

 Asp Ala Leu Ala Glu Ala Gln Arg Val Asn Thr Lys Ser Gln Ser
                 305                 310                 315

 Ala Phe Asp Leu Lys Lys Lys Asn Leu Ala Cys Glu Glu Ser Lys
                 320                 325                 330

 Arg Lys Glu Leu Glu Lys Asn Met Val Glu Asp Ser Lys Thr Leu
                 335                 340                 345

 Ala Ala Lys Glu Lys Glu Val Lys Lys Ile Thr Asp Gly Leu His
                 350                 355                 360

 Ala Leu Gln Glu Ala Ser Asn Lys Asp Ala Glu Ala Leu Ala Ala
                 365                 370                 375

 Ala Gln Gln His Phe Asn Ala Val Ser Ala Gly Leu Ser Ser Asn
                 380                 385                 390

 Glu Asp Gly Ala Glu Ala Thr Leu Ala Gly Gln Met Met Ala Cys
                 395                 400                 405

 Lys Asn Asp Ile Ser Lys Ala Gln Thr Glu Ala Lys Gln Ala Gln
                 410                 415                 420

 Met Lys Leu Lys His Ala Gln Gln Glu Leu Lys Asn Lys Gln Ala
                 425                 430                 435

 Glu Val Lys Lys Met Asp Ser Gly Tyr Arg Lys Asp Gln Glu Ala
                 440                 445                 450

 Leu Glu Ala Val Lys Arg Leu Lys Glu Lys Leu Glu Ala Glu Met
                 455                 460                 465

 Lys Lys Leu Asn Tyr Glu Glu Asn Lys Glu Glu Ser Leu Leu Glu
                 470                 475                 480

 Lys Arg Arg Gln Leu Ser Arg Asp Ile Gly Arg Leu Lys Glu Thr
                 485                 490                 495

 Tyr Glu Ala Leu Leu Ala Arg Phe Pro Asn Leu Arg Phe Ala Tyr
                 500                 505                 510

 Lys Asp Pro Glu Lys Asn Trp Asn Arg Asn Cys Val Lys Gly Leu
                 515                 520                 525

 Val Ala Ser Leu Ile Ser Val Lys Asp Thr Ser Ala Thr Thr Ala
                 530                 535                 540

 Leu Glu Leu Val Ala Gly Glu Arg Leu Tyr Asn Val Val Val Asp
                 545                 550                 555

 Thr Glu Val Thr Gly Lys Lys Leu Leu Glu Arg Gly Glu Leu Lys
                 560                 565                 570

 Arg Arg Tyr Thr Ile Ile Pro Leu Asn Lys Ile Ser Ala Arg Cys
                 575                 580                 585

 Ile Ala Pro Glu Thr Leu Arg Val Ala Gln Asn Leu Val Gly Pro
                 590                 595                 600

 Asp Asn Val His Val Ala Leu Ser Leu Val Glu Tyr Lys Pro Glu
                 605                 610                 615

 Leu Gln Lys Ala Met Glu Phe Val Phe Gly Thr Thr Phe Val Cys
                 620                 625                 630

 Asp Asn Met Asp Asn Ala Lys Lys Val Ala Phe Asp Lys Arg Ile
                 635                 640                 645

 Met Thr Arg Thr Val Thr Leu Gly Gly Asp Val Phe Asp Pro His
                 650                 655                 660

 Gly Thr Leu Ser Gly Gly Ala Arg Ser Gln Ala Ala Ser Ile Leu
                 665                 670                 675

 Thr Lys Phe Gln Glu Leu Lys Asp Val Gln Asp Glu Leu Arg Ile
                 680                 685                 690

 Lys Glu Asn Glu Leu Arg Ala Leu Glu Glu Glu Leu Ala Gly Leu
                 695                 700                 705

 Lys Asn Thr Ala Glu Lys Tyr Arg Gln Leu Lys Gln Gln Trp Glu
                 710                 715                 720

 Met Lys Thr Glu Glu Ala Asp Leu Leu Gln Thr Lys Leu Gln Gln
                 725                 730                 735

 Ser Ser Tyr His Lys Gln Gln Glu Glu Leu Asp Ala Leu Lys Lys
                 740                 745                 750

 Thr Ile Glu Glu Ser Glu Glu Thr Leu Lys Asn Thr Lys Glu Ile
                 755                 760                 765

 Gln Arg Lys Ala Glu Glu Lys Tyr Glu Val Leu Glu Asn Lys Met
                 770                 775                 780

 Lys Asn Ala Glu Ala Glu Arg Glu Arg Glu Leu Lys Asp Ala Gln
                 785                 790                 795

 Lys Lys Leu Asp Cys Ala Lys Thr Lys Ala Asp Ala Ser Ser Lys
                 800                 805                 810

 Lys Met Lys Glu Lys Gln Gln Glu Val Glu Ala Ile Thr Leu Glu
                 815                 820                 825

 Leu Glu Glu Leu Lys Arg Glu His Thr Ser Tyr Lys Gln Gln Leu
                 830                 835                 840

 Glu Ala Val Asn Glu Ala Ile Lys Ser Tyr Glu Ser Gln Ile Glu
                 845                 850                 855

 Val Met Ala Ala Glu Val Ala Lys Asn Lys Glu Ser Val Asn Lys
                 860                 865                 870

 Ala Gln Glu Glu Val Thr Lys Gln Lys Glu Val Ile Thr Ala Gln
                 875                 880                 885

 Asp Thr Val Ile Lys Leu Asn Met Gln Lys Trp Gln Asn Thr Arg
                 890                 895                 900

 Ser Lys Thr Met Ile Leu Ser Leu Lys Ile Lys Glu Leu Asp His
                 905                 910                 915

 His Ile Ser Lys His Lys Arg Glu Ala Glu Asp Gly Ala Ala Lys
                 920                 925                 930

 Val Ser Lys Met Leu Lys Asp Tyr Asp Trp Ile Asn Ala Glu Arg
                 935                 940                 945

 His Leu Phe Gly Gln Pro Asn Ser Ala Tyr Asp Phe Lys Thr Asn
                 950                 955                 960

 Asn Pro Lys Glu Ala Gly Gln Arg Leu Gln Lys Leu Gln Glu Met
                 965                 970                 975

 Lys Glu Lys Leu Gly Arg Asn Val Asn Met Arg Ala Met Asn Val
                 980                 985                 990

 Leu Thr Glu Ala Glu Glu Arg Cys Asn Asp Leu Met Lys Lys Lys
                 995                1000                1005

 Arg Ile Val Glu Asn Asp Lys Ser Lys Ile Leu Thr Thr Ile Glu
                1010                1015                1020

 Asp Leu Asp Gln Lys Lys Asn Gln Ala Leu Asn Ile Ala Trp Gln
                1025                1030                1035

 Lys Val Asn Lys Asp Phe Gly Ser Ile Phe Ser Thr Leu Leu Pro
                1040                1045                1050

 Gly Ala Asn Ala Met Leu Ala Pro Pro Glu Gly Gln Thr Val Leu
                1055                1060                1065

 Asp Gly Leu Glu Phe Lys Val Ala Leu Gly Asn Thr Trp Lys Glu
                1070                1075                1080

 Asn Leu Thr Glu Leu Ser Gly Gly Gln Arg Ser Leu Val Ala Leu
                1085                1090                1095

 Ser Leu Ile Leu Ser Met Leu Leu Phe Lys Pro Ala Pro Ile Tyr
                1100                1105                1110

 Ile Leu Asp Glu Val Asp Ala Ala Leu Asp Leu Ser His Thr Gln
                1115                1120                1125

 Asn Ile Gly Gln Met Leu Arg Thr His Phe Thr His Ser Gln Phe
                1130                1135                1140

 Ile Val Val Ser Leu Lys Glu Gly Met Phe Asn Asn Ala Asn Val
                1145                1150                1155

 Leu Phe Lys Thr Lys Phe Val Asp Gly Val Ser Thr Val Ala Arg
                1160                1165                1170

 Phe Thr Gln Cys Gln Asn Gly Lys Ile Ser Lys Glu Ala Lys Ser
                1175                1180                1185

 Lys Ala Lys Pro Pro Lys Gly Ala His Val Glu Val
                1190                1195

<210> 6070
<211> 1427
<212> DNA
<213> Homo sapien

<400> 6070
 tgggtgttgg aggctttaag gtagctttaa attcgtgttg tcctgggagc 50

 tcgccctttt cggctggagt cgggctttac ggcgccggat ggctctggac 100

 gtgaagtctc gggcaaagcg ttatgagaag ctggacttcc ttggggaggg 150

 acagtttgcc accgtttaca aggccagaga taagaatacc aaccaaattg 200

 tcgccattaa gaaaatcaaa cttggacata gatcagaagc taaagatggt 250

 ataaatagaa ccgccttaag agagataaaa ttattacagg agctaagtca 300

 tccaaatata attggtctcc ttgatgcttt tggacataaa tctaatatta 350

 gccttgtctt tgattttatg gaaactgatc tagaggttat aataaaggat 400

 aatagtcttg tgctgacacc atcacacatc aaagcctaca tgttgatgac 450

 tcttcaagga ttagaatatt tacatcaaca ttggatccta catagggatc 500

 tgaaaccaaa caacttgttg ctagatgaaa atggagttct aaaactggca 550

 gattttggcc tggccaaatc ttttgggagc cccaatagag cttatacaca 600

 tcaggttgta accaggtggt atcgggcccc cgagttacta tttggagcta 650

 ggatgtatgg tgtaggtgtg gacatgtggg ctgttggctg tatattagca 700

 gagttacttc taagggttcc ttttttgcca ggagattcag accttgatca 750

 gctaacaaga atatttgaaa ctttgggcac accaactgag gaacagtggc 800

 cggacatgtg tagtcttcca gattatgtga catttaagag tttccctgga 850

 atacctttgc atcacatctt cagtgcagca ggagacgact tactagatct 900

 catacaaggc ttattcttat ttaatccatg tgctcgaatt acggccacac 950

 aggcactgaa aatgaagtat ttcagtaatc ggccagggcc aacacctgga 1000

 tgtcagctgc caagaccaaa ctgtccagtg gaaaccttaa aggagcaatc 1050

 aaatccagct ttggcaataa aaaggaaaag aacagaggcc ttagaacaag 1100

 gaggattgcc caagaaacta attttttaaa gagaacactg gacaacattt 1150

 tactactgag ggaaatagcc aaaaaggcaa ataatggaaa aatagtaaac 1200

 attaagtaaa tgctgtagaa gtgagtttgt aaatattcta cacatgtaaa 1250

 atatgtaaaa ctatgggtta tttttattaa atgtatttta aaataaaaat 1300

 ttaattctgg tttttctgat tagagtccca aagtgagaaa agttcaatac 1350

 tcttgaaatg tagaattgaa aatgcattag ggaaaactta ataaaaatta 1400

 ttaccagtta tttggaaaaa aaaaaaa 1427

<210> 6071
<211> 346
<212> PRT
<213> Homo sapien

<400> 6071
 Met Ala Leu Asp Val Lys Ser Arg Ala Lys Arg Tyr Glu Lys Leu
   1               5                  10                  15

 Asp Phe Leu Gly Glu Gly Gln Phe Ala Thr Val Tyr Lys Ala Arg
                  20                  25                  30

 Asp Lys Asn Thr Asn Gln Ile Val Ala Ile Lys Lys Ile Lys Leu
                  35                  40                  45

 Gly His Arg Ser Glu Ala Lys Asp Gly Ile Asn Arg Thr Ala Leu
                  50                  55                  60

 Arg Glu Ile Lys Leu Leu Gln Glu Leu Ser His Pro Asn Ile Ile
                  65                  70                  75

 Gly Leu Leu Asp Ala Phe Gly His Lys Ser Asn Ile Ser Leu Val
                  80                  85                  90

 Phe Asp Phe Met Glu Thr Asp Leu Glu Val Ile Ile Lys Asp Asn
                  95                 100                 105

 Ser Leu Val Leu Thr Pro Ser His Ile Lys Ala Tyr Met Leu Met
                 110                 115                 120

 Thr Leu Gln Gly Leu Glu Tyr Leu His Gln His Trp Ile Leu His
                 125                 130                 135

 Arg Asp Leu Lys Pro Asn Asn Leu Leu Leu Asp Glu Asn Gly Val
                 140                 145                 150

 Leu Lys Leu Ala Asp Phe Gly Leu Ala Lys Ser Phe Gly Ser Pro
                 155                 160                 165

 Asn Arg Ala Tyr Thr His Gln Val Val Thr Arg Trp Tyr Arg Ala
                 170                 175                 180

 Pro Glu Leu Leu Phe Gly Ala Arg Met Tyr Gly Val Gly Val Asp
                 185                 190                 195

 Met Trp Ala Val Gly Cys Ile Leu Ala Glu Leu Leu Leu Arg Val
                 200                 205                 210

 Pro Phe Leu Pro Gly Asp Ser Asp Leu Asp Gln Leu Thr Arg Ile
                 215                 220                 225

 Phe Glu Thr Leu Gly Thr Pro Thr Glu Glu Gln Trp Pro Asp Met
                 230                 235                 240

 Cys Ser Leu Pro Asp Tyr Val Thr Phe Lys Ser Phe Pro Gly Ile
                 245                 250                 255

 Pro Leu His His Ile Phe Ser Ala Ala Gly Asp Asp Leu Leu Asp
                 260                 265                 270

 Leu Ile Gln Gly Leu Phe Leu Phe Asn Pro Cys Ala Arg Ile Thr
                 275                 280                 285

 Ala Thr Gln Ala Leu Lys Met Lys Tyr Phe Ser Asn Arg Pro Gly
                 290                 295                 300

 Pro Thr Pro Gly Cys Gln Leu Pro Arg Pro Asn Cys Pro Val Glu
                 305                 310                 315

 Thr Leu Lys Glu Gln Ser Asn Pro Ala Leu Ala Ile Lys Arg Lys
                 320                 325                 330

 Arg Thr Glu Ala Leu Glu Gln Gly Gly Leu Pro Lys Lys Leu Ile
                 335                 340                 345

 Phe


<210> 6072
<211> 1535
<212> DNA
<213> Homo sapien

<400> 6072
 cctccgctca gtccgggagc gcacgtgggc cgcggcgctc cgacctccgc 50

 tttcccaccg cccgcagctg aagcacatcc cgcagcccgg cgcggactcc 100

 gatcgccgca gttgccctct ggcgccatgt cgcagaacgg agcgcccggg 150

 atgcaggagg agagcctgca gggctcctgg gtagaactgc acttcagcaa 200

 taatgggaac gggggcagcg ttccagcctc ggtttctatt tataatggag 250

 acatggaaaa aatactgctg gacgcacagc atgagtctgg acggagtagc 300

 tccaagagct ctcactgtga cagcccacct cgctcgcaga caccacaaga 350

 taccaacagg gcttctgaaa cagataccca tagcattgga gagaaaaaca 400

 gctcacagtc tgaggaagat gatattgaaa gaaggaaaga agttgaaagc 450

 atcttgaaga aaaactcaga ttggatatgg gattggtcaa gtcggccgga 500

 aaatattccc cccaaggagt tcctctttaa acacccgaag cgcacggcca 550

 ccctcagcat gaggaacacg agcgtcatga agaaaggggg catattctct 600

 gcagaatttc tgaaagtttt ccttccatct ctgctgctct ctcatttgct 650

 ggccatcgga ttggggatct atattggaag gcgtctgaca acctccacca 700

 gcaccttttg atgaagaact ggagtctgac ttggttcgtt agtggattac 750

 ttctgagctt gcaacatagc tcactgaaga gctgttagat cctggggtgg 800

 ccacgtcact tgtgtttatt tgttctgtaa atgctgcgtt cctaatttag 850

 taaaataaaa gaatagacac taaaatcatg ttgatctata attacaccta 900

 tgggatcaat aagcatgtca gactgattaa tgtctactgt gaaaatttgg 950

 tagtaaattt tcatttgata ttagatataa atatctgaat ataaataatt 1000

 ttaatatact agtcatgatg tgtgttgtat tttaaaaatt atctgcaacc 1050

 ttaattcagc tgaagtactt tatatttcaa aagaatgaat aacattgata 1100

 ataaaatcgc tactttaagg ggtttgtcca aaataaatat tgtggcctta 1150

 tatatcacac tattgtagaa agtattattt aatttaaatg gatgcaggtt 1200

 gtctactaaa gaaagattat atataactat gctaattgtt cataatcaac 1250

 agaaaccaag atagagctac aaactcagct gtacagttcg tacactaaac 1300

 tcttcttgct tttgcattat aaggaattaa gtctccgatt attaggtgat 1350

 caccctggat gatcagtttt ctgctgaagg cacctactca gtatcttttc 1400

 ctctttatca ctctgcattg gtgaatttaa tcctctcctt tgtgttcaac 1450

 ttttgtgtgc ttttaaaatc agctttattc taagcaaatc tgtgtctact 1500

 ttaaaaaact ggaaatggaa aaaaaaataa atctt 1535

<210> 6073
<211> 194
<212> PRT
<213> Homo sapien

<400> 6073
 Met Ser Gln Asn Gly Ala Pro Gly Met Gln Glu Glu Ser Leu Gln
   1               5                  10                  15

 Gly Ser Trp Val Glu Leu His Phe Ser Asn Asn Gly Asn Gly Gly
                  20                  25                  30

 Ser Val Pro Ala Ser Val Ser Ile Tyr Asn Gly Asp Met Glu Lys
                  35                  40                  45

 Ile Leu Leu Asp Ala Gln His Glu Ser Gly Arg Ser Ser Ser Lys
                  50                  55                  60

 Ser Ser His Cys Asp Ser Pro Pro Arg Ser Gln Thr Pro Gln Asp
                  65                  70                  75

 Thr Asn Arg Ala Ser Glu Thr Asp Thr His Ser Ile Gly Glu Lys
                  80                  85                  90

 Asn Ser Ser Gln Ser Glu Glu Asp Asp Ile Glu Arg Arg Lys Glu
                  95                 100                 105

 Val Glu Ser Ile Leu Lys Lys Asn Ser Asp Trp Ile Trp Asp Trp
                 110                 115                 120

 Ser Ser Arg Pro Glu Asn Ile Pro Pro Lys Glu Phe Leu Phe Lys
                 125                 130                 135

 His Pro Lys Arg Thr Ala Thr Leu Ser Met Arg Asn Thr Ser Val
                 140                 145                 150

 Met Lys Lys Gly Gly Ile Phe Ser Ala Glu Phe Leu Lys Val Phe
                 155                 160                 165

 Leu Pro Ser Leu Leu Leu Ser His Leu Leu Ala Ile Gly Leu Gly
                 170                 175                 180

 Ile Tyr Ile Gly Arg Arg Leu Thr Thr Ser Thr Ser Thr Phe
                 185                 190

<210> 6074
<211> 1818
<212> DNA
<213> Homo sapien

<400> 6074
 accacaccaa gcagcggctg ggggggggaa agacgaggaa agaggaggaa 50

 aacaaaagct gctacttatg gaagatacaa aggagtctaa cgtgaagaca 100

 ttttgctcca agaatatcct agccatcctt ggcttctcct ctatcatagc 150

 tgtgatagct ttgcttgctg tggggttgac ccagaacaaa gcattgccag 200

 aaaacgttaa gtatgggatt gtgctggatg cgggttcttc tcacacaagt 250

 ttatacatct ataagtggcc agcagaaaag gagaatgaca caggcgtggt 300

 gcatcaagta gaagaatgca gggttaaagg tcctggaatc tcaaaatttg 350

 ttcagaaagt aaatgaaata ggcatttacc tgactgattg catggaaaga 400

 gctagggaag tgattccaag gtcccagcac caagagacac ccgtttacct 450

 gggagccacg gcaggcatgc ggttgctcag gatggaaagt gaagagttgg 500

 cagacagggt tctggatgtg gtggagagga gcctcagcaa ctaccccttt 550

 gacttccagg gtgccaggat cattactggc caagaggaag gtgcctatgg 600

 ctggattact atcaactatc tgctgggcaa attcagtcag aaaacaaggt 650

 ggttcagcat agtcccatat gaaaccaata atcaggaaac ctttggagct 700

 ttggaccttg ggggagcctc tacacaagtc acttttgtac cccaaaacca 750

 gactatcgag tccccagata atgctctgca atttcgcctc tatggcaagg 800

 actacaatgt ctacacacat agcttcttgt gctatgggaa ggatcaggca 850

 ctctggcaga aactggccaa ggacattcag gttgcaagta atgaaattct 900

 cagggaccca tgctttcatc ctggatataa gaaggtagtg aacgtaagtg 950

 acctttacaa gaccccctgc accaagagat ttgagatgac tcttccattc 1000

 cagcagtttg aaatccaggg tattggaaac tatcaacaat gccatcaaag 1050

 catcctggag ctcttcaaca ccagttactg cccttactcc cagtgtgcct 1100

 tcaatgggat tttcttgcca ccactccagg gggattttgg ggcattttca 1150

 gctttttact ttgtgatgaa gtttttaaac ttgacatcag agaaagtctc 1200

 tcaggaaaag gtgactgaga tgatgaaaaa gttctgtgct cagccttggg 1250

 aggagataaa aacatcttac gctggagtaa aggagaagta cctgagtgaa 1300

 tactgctttt ctggtaccta cattctctcc ctccttctgc aaggctatca 1350

 tttcacagct gattcctggg agcacatcca tttcattggc aagatccagg 1400

 gcagcgacgc cggctggact ttgggctaca tgctgaacct gaccaacatg 1450

 atcccagctg agcaaccatt gtccacacct ctctcccact ccacctatgt 1500

 cttcctcatg gttctattct ccctggtcct tttcacagtg gccatcatag 1550

 gcttgcttat ctttcacaag ccttcatatt tctggaaaga tatggtatag 1600

 caaaagcagc tgaaatatgc tggctggagt gaggaaaaaa tcgtccaggg 1650

 agcattttcc tccatcgcag tgttcaaggc catccttccc tgtctgccag 1700

 ggccagtctt gacgagtgtg aagcttcctt ggcttttact gaagcctttc 1750

 ttttggaggt attcaatatc ctttgcctca aggacttcgg cagatactgt 1800

 ctctttcatg agtttttc 1818

<210> 6075
<211> 510
<212> PRT
<213> Homo sapien

<400> 6075
 Met Glu Asp Thr Lys Glu Ser Asn Val Lys Thr Phe Cys Ser Lys
   1               5                  10                  15

 Asn Ile Leu Ala Ile Leu Gly Phe Ser Ser Ile Ile Ala Val Ile
                  20                  25                  30

 Ala Leu Leu Ala Val Gly Leu Thr Gln Asn Lys Ala Leu Pro Glu
                  35                  40                  45

 Asn Val Lys Tyr Gly Ile Val Leu Asp Ala Gly Ser Ser His Thr
                  50                  55                  60

 Ser Leu Tyr Ile Tyr Lys Trp Pro Ala Glu Lys Glu Asn Asp Thr
                  65                  70                  75

 Gly Val Val His Gln Val Glu Glu Cys Arg Val Lys Gly Pro Gly
                  80                  85                  90

 Ile Ser Lys Phe Val Gln Lys Val Asn Glu Ile Gly Ile Tyr Leu
                  95                 100                 105

 Thr Asp Cys Met Glu Arg Ala Arg Glu Val Ile Pro Arg Ser Gln
                 110                 115                 120

 His Gln Glu Thr Pro Val Tyr Leu Gly Ala Thr Ala Gly Met Arg
                 125                 130                 135

 Leu Leu Arg Met Glu Ser Glu Glu Leu Ala Asp Arg Val Leu Asp
                 140                 145                 150

 Val Val Glu Arg Ser Leu Ser Asn Tyr Pro Phe Asp Phe Gln Gly
                 155                 160                 165

 Ala Arg Ile Ile Thr Gly Gln Glu Glu Gly Ala Tyr Gly Trp Ile
                 170                 175                 180

 Thr Ile Asn Tyr Leu Leu Gly Lys Phe Ser Gln Lys Thr Arg Trp
                 185                 190                 195

 Phe Ser Ile Val Pro Tyr Glu Thr Asn Asn Gln Glu Thr Phe Gly
                 200                 205                 210

 Ala Leu Asp Leu Gly Gly Ala Ser Thr Gln Val Thr Phe Val Pro
                 215                 220                 225

 Gln Asn Gln Thr Ile Glu Ser Pro Asp Asn Ala Leu Gln Phe Arg
                 230                 235                 240

 Leu Tyr Gly Lys Asp Tyr Asn Val Tyr Thr His Ser Phe Leu Cys
                 245                 250                 255

 Tyr Gly Lys Asp Gln Ala Leu Trp Gln Lys Leu Ala Lys Asp Ile
                 260                 265                 270

 Gln Val Ala Ser Asn Glu Ile Leu Arg Asp Pro Cys Phe His Pro
                 275                 280                 285

 Gly Tyr Lys Lys Val Val Asn Val Ser Asp Leu Tyr Lys Thr Pro
                 290                 295                 300

 Cys Thr Lys Arg Phe Glu Met Thr Leu Pro Phe Gln Gln Phe Glu
                 305                 310                 315

 Ile Gln Gly Ile Gly Asn Tyr Gln Gln Cys His Gln Ser Ile Leu
                 320                 325                 330

 Glu Leu Phe Asn Thr Ser Tyr Cys Pro Tyr Ser Gln Cys Ala Phe
                 335                 340                 345

 Asn Gly Ile Phe Leu Pro Pro Leu Gln Gly Asp Phe Gly Ala Phe
                 350                 355                 360

 Ser Ala Phe Tyr Phe Val Met Lys Phe Leu Asn Leu Thr Ser Glu
                 365                 370                 375

 Lys Val Ser Gln Glu Lys Val Thr Glu Met Met Lys Lys Phe Cys
                 380                 385                 390

 Ala Gln Pro Trp Glu Glu Ile Lys Thr Ser Tyr Ala Gly Val Lys
                 395                 400                 405

 Glu Lys Tyr Leu Ser Glu Tyr Cys Phe Ser Gly Thr Tyr Ile Leu
                 410                 415                 420

 Ser Leu Leu Leu Gln Gly Tyr His Phe Thr Ala Asp Ser Trp Glu
                 425                 430                 435

 His Ile His Phe Ile Gly Lys Ile Gln Gly Ser Asp Ala Gly Trp
                 440                 445                 450

 Thr Leu Gly Tyr Met Leu Asn Leu Thr Asn Met Ile Pro Ala Glu
                 455                 460                 465

 Gln Pro Leu Ser Thr Pro Leu Ser His Ser Thr Tyr Val Phe Leu
                 470                 475                 480

 Met Val Leu Phe Ser Leu Val Leu Phe Thr Val Ala Ile Ile Gly
                 485                 490                 495

 Leu Leu Ile Phe His Lys Pro Ser Tyr Phe Trp Lys Asp Met Val
                 500                 505                 510

<210> 6076
<211> 2076
<212> DNA
<213> Homo sapien

<400> 6076
 gctggagccg gcgcggagga gcgggcggcc gcggctgtgc cctctcctac 50

 tcctcaccgc gcgcgcgcgg ggaaccagta gccgcggctg cttcggttgc 100

 cgcggtcggt ggtcgttatg gattctccat gggacgagtt ggctctggcc 150

 ttctcccgca cgtccatgtt tccctttttt gacatcgcgc actatctagt 200

 gtcagtgatg gcggtgaaac gtcagccggg agcagctgca ttggcatgga 250

 agaatcctat ttcaagctgg tttactgcta tgctccactg ttttggtgga 300

 ggaattttat cctgtctact gcttgcagag cctccattga agtttcttgc 350

 aaaccacact aacatattac tggcatcttc aatctggtat attacatttt 400

 tttgcccgca tgacctagtt tcccagggct attcatatct acctgttcaa 450

 ctactggctt cgggaatgaa ggaagtgacc agaacttgga aaatagtagg 500

 tggagtcaca catgctaata gctattacaa aaatggctgg atagtcatga 550

 tagctattgg atgggcccga ggtgcaggtg gtaccattat aacgaatttt 600

 gagaggttgg taaaaggaga ttggaaacca gaaggtgatg aatggctgaa 650

 gatgtcatac cctgccaagg taaccctgct ggggtcagtt atcttcacat 700

 tccagcacac ccagcatctg gcaatatcaa agcataatct tatgttcctt 750

 tataccatct ttattgtggc cacaaagata accatgatga ctacacagac 800

 ttctactatg acatttgctc cttttgagga tacattgagt tggatgctat 850

 ttggctggca gcagccgttt tcatcatgtg agaagaaaag tgaagcaaag 900

 tcaccttcca atggcgttgg gtcattggcc tcaaagccgg tagatgttgc 950

 ctcagataat gttaaaaaga aacatactaa gaagaatgaa taaatttacg 1000

 tgatgagctc tacaaggcca aaaatttttt ttcttatcta cctgttatat 1050

 tgtgctaatt tttctatgta tgtgatgtga aatgaagact atatatatgg 1100

 aatggaggtg acagaaagaa agaaattctt tgtttgaggg agacttcccc 1150

 tttctggatt gtatttgtag agtgttacga gtgtatcatg tgattatgct 1200

 ttaccggtat aagagattct gttgtgatta tttgaatagt tttatattaa 1250

 taaaagaaga caaaattttt taaatgttag aaaaagcaga tctgtcattg 1300

 caaagtaaca aaaattttaa gcttttaaaa atgtagattt ttcatatttt 1350

 taaaatttga atctatttga gctttagttc agcagaatta aatttttact 1400

 tgacattatc attaaaattg ctaggtatgg agaacaattc ctattttatt 1450

 ttgaacactg agaagagtaa acttttccta aaacacttta tattataaat 1500

 gaaaataaat tgctagttta tattttagat ataaacatca tattttttat 1550

 taatacctac atcaaatgga aaatatctga aatttttttt ccatagcagg 1600

 tattttctac tagaagtagt tttactactt ttcatttaga acagagtatg 1650

 agtcttaatc tgaagtcttt ttcatgccct tgttttaaaa aaactacttt 1700

 ttttggcctc aaaaaaatca agggtgtaat ttttaataaa ttgttaatcc 1750

 tatgttttgt aattttcatt ttaggagctt gacttatttt tttctctctc 1800

 ataaaaacac atttgtttta attgtaggag aaattttctc agcattttgc 1850

 atgttctttc taatctttgt tggtctgaat atattggtag taattactgt 1900

 aattattcaa caaaaagcat atccgttcaa aaatttttcc actatgtctt 1950

 ttttctagtg gctactgttt tagttttcta gttgaatatc tctgacaagc 2000

 tttcgtatgg ttttgttata tcttcatcta catgtaatgt gttattaatt 2050

 ttattaaatg aaaactaatc accttc 2076

<210> 6077
<211> 291
<212> PRT
<213> Homo sapien

<400> 6077
 Met Asp Ser Pro Trp Asp Glu Leu Ala Leu Ala Phe Ser Arg Thr
   1               5                  10                  15

 Ser Met Phe Pro Phe Phe Asp Ile Ala His Tyr Leu Val Ser Val
                  20                  25                  30

 Met Ala Val Lys Arg Gln Pro Gly Ala Ala Ala Leu Ala Trp Lys
                  35                  40                  45

 Asn Pro Ile Ser Ser Trp Phe Thr Ala Met Leu His Cys Phe Gly
                  50                  55                  60

 Gly Gly Ile Leu Ser Cys Leu Leu Leu Ala Glu Pro Pro Leu Lys
                  65                  70                  75

 Phe Leu Ala Asn His Thr Asn Ile Leu Leu Ala Ser Ser Ile Trp
                  80                  85                  90

 Tyr Ile Thr Phe Phe Cys Pro His Asp Leu Val Ser Gln Gly Tyr
                  95                 100                 105

 Ser Tyr Leu Pro Val Gln Leu Leu Ala Ser Gly Met Lys Glu Val
                 110                 115                 120

 Thr Arg Thr Trp Lys Ile Val Gly Gly Val Thr His Ala Asn Ser
                 125                 130                 135

 Tyr Tyr Lys Asn Gly Trp Ile Val Met Ile Ala Ile Gly Trp Ala
                 140                 145                 150

 Arg Gly Ala Gly Gly Thr Ile Ile Thr Asn Phe Glu Arg Leu Val
                 155                 160                 165

 Lys Gly Asp Trp Lys Pro Glu Gly Asp Glu Trp Leu Lys Met Ser
                 170                 175                 180

 Tyr Pro Ala Lys Val Thr Leu Leu Gly Ser Val Ile Phe Thr Phe
                 185                 190                 195

 Gln His Thr Gln His Leu Ala Ile Ser Lys His Asn Leu Met Phe
                 200                 205                 210

 Leu Tyr Thr Ile Phe Ile Val Ala Thr Lys Ile Thr Met Met Thr
                 215                 220                 225

 Thr Gln Thr Ser Thr Met Thr Phe Ala Pro Phe Glu Asp Thr Leu
                 230                 235                 240

 Ser Trp Met Leu Phe Gly Trp Gln Gln Pro Phe Ser Ser Cys Glu
                 245                 250                 255

 Lys Lys Ser Glu Ala Lys Ser Pro Ser Asn Gly Val Gly Ser Leu
                 260                 265                 270

 Ala Ser Lys Pro Val Asp Val Ala Ser Asp Asn Val Lys Lys Lys
                 275                 280                 285

 His Thr Lys Lys Asn Glu
                 290

<210> 6078
<211> 1709
<212> DNA
<213> Homo sapien

<400> 6078
 caatttgagt ttccatttct cggatttggg aactggtata agcattgtct 50

 gtgatgtaaa caaagtcttc aatatttgga gaaaacatct cctcatactt 100

 gagagcacaa gaggaagaga gagaccctca ctgctgggga gtccctgcca 150

 cactcagtcc cccaccacac tgaatcggaa ttccgagagg gaagaggagg 200

 cgcgagaatg gaggtggagg ccgtctgtgg tggcgcgggc gaggtggagg 250

 cccaggactc tgaccctgcc cctgccttca gcaaggcccc cggcagcgcc 300

 ggccactacg aactgccgtg ggttgaaaaa tataggccag taaagctgaa 350

 tgaaattgtc gggaatgaag acaccgtgag caggctagag gtctttgcaa 400

 gggaaggaaa tgtgcccaac atcatcattg cgggccctcc aggaaccggc 450

 aagaccacaa gcattctgtg cttggcccgg gccctgctgg gcccagcact 500

 caaagatgcc atgttggaac tcaatgcttc aaatgacagg ggcattgacg 550

 ttgtgaggaa taaaattaaa atgtttgctc aacaaaaagt cactcttccc 600

 aaaggccgac ataagatcat cattctggat gaagcagaca gcatgaccga 650

 cggagcccag caagccttga ggagaaccat ggaaatctac tctaaaacca 700

 ctcgcttcgc ccttgcttgt aatgcttcgg ataagatcat cgagcccatt 750

 cagtcccgct gtgcagtcct ccggtacaca aagctgaccg acgcccagat 800

 cctcaccagg ctgatgaatg ttatcgagaa ggagagggta ccctacactg 850

 atgacggcct agaagccatc atcttcacgg cccagggaga catgaggcag 900

 gcgctgaaca acctgcagtc caccttctca ggatttggct tcattaacag 950

 tgagaacgtg ttcaaggtct gtgacgagcc ccacccactg ctggtaaagg 1000

 agatgatcca gcactgtgtg aatgccaaca ttgacgaagc ctacaagatt 1050

 cttgctcact tgtggcatct gggctactca ccagaagata tcattggcaa 1100

 catctttcga gtgtgtaaaa ctttccaaat ggcagaatac ctgaaactgg 1150

 agtttatcaa ggaaattgga tacactcaca tgaaaatagc ggaaggagtg 1200

 aactctcttt tgcagatggc aggcctcctg gcaaggctgt gtcagaagac 1250

 aatggccccg gtggccagtt agagcagaga cttcactgac tgacttacag 1300

 gtgccctatt ctgaggtaca ggagccgcgg ctttctgatg ggggaaaatg 1350

 cgccttaggc tgagccaaca tgactgtccc ccaaactcca gtggctggcc 1400

 aggcgcggta gtcacgcctg taatcccaac actttgggag gccgaggcag 1450

 gtggatcacc tgaggtcaga agttcaagac cagcctggcc aacatgggga 1500

 aaccctgtct ttactaaaaa tataaaaatt agctgggtgt ggtggcgggc 1550

 acctgtaatc ccagctactc gggaggctgt ggcaggcgaa atcgcttgaa 1600

 cccaggagga ggaggtggag gttgcagtga gccaagatca caccattgca 1650

 ctccagcctg ggcgacagag actccatctg gggaaaaaaa ttaaataaat 1700

 aaactcccg 1709

<210> 6079
<211> 354
<212> PRT
<213> Homo sapien

<400> 6079
 Met Glu Val Glu Ala Val Cys Gly Gly Ala Gly Glu Val Glu Ala
   1               5                  10                  15

 Gln Asp Ser Asp Pro Ala Pro Ala Phe Ser Lys Ala Pro Gly Ser
                  20                  25                  30

 Ala Gly His Tyr Glu Leu Pro Trp Val Glu Lys Tyr Arg Pro Val
                  35                  40                  45

 Lys Leu Asn Glu Ile Val Gly Asn Glu Asp Thr Val Ser Arg Leu
                  50                  55                  60

 Glu Val Phe Ala Arg Glu Gly Asn Val Pro Asn Ile Ile Ile Ala
                  65                  70                  75

 Gly Pro Pro Gly Thr Gly Lys Thr Thr Ser Ile Leu Cys Leu Ala
                  80                  85                  90

 Arg Ala Leu Leu Gly Pro Ala Leu Lys Asp Ala Met Leu Glu Leu
                  95                 100                 105

 Asn Ala Ser Asn Asp Arg Gly Ile Asp Val Val Arg Asn Lys Ile
                 110                 115                 120

 Lys Met Phe Ala Gln Gln Lys Val Thr Leu Pro Lys Gly Arg His
                 125                 130                 135

 Lys Ile Ile Ile Leu Asp Glu Ala Asp Ser Met Thr Asp Gly Ala
                 140                 145                 150

 Gln Gln Ala Leu Arg Arg Thr Met Glu Ile Tyr Ser Lys Thr Thr
                 155                 160                 165

 Arg Phe Ala Leu Ala Cys Asn Ala Ser Asp Lys Ile Ile Glu Pro
                 170                 175                 180

 Ile Gln Ser Arg Cys Ala Val Leu Arg Tyr Thr Lys Leu Thr Asp
                 185                 190                 195

 Ala Gln Ile Leu Thr Arg Leu Met Asn Val Ile Glu Lys Glu Arg
                 200                 205                 210

 Val Pro Tyr Thr Asp Asp Gly Leu Glu Ala Ile Ile Phe Thr Ala
                 215                 220                 225

 Gln Gly Asp Met Arg Gln Ala Leu Asn Asn Leu Gln Ser Thr Phe
                 230                 235                 240

 Ser Gly Phe Gly Phe Ile Asn Ser Glu Asn Val Phe Lys Val Cys
                 245                 250                 255

 Asp Glu Pro His Pro Leu Leu Val Lys Glu Met Ile Gln His Cys
                 260                 265                 270

 Val Asn Ala Asn Ile Asp Glu Ala Tyr Lys Ile Leu Ala His Leu
                 275                 280                 285

 Trp His Leu Gly Tyr Ser Pro Glu Asp Ile Ile Gly Asn Ile Phe
                 290                 295                 300

 Arg Val Cys Lys Thr Phe Gln Met Ala Glu Tyr Leu Lys Leu Glu
                 305                 310                 315

 Phe Ile Lys Glu Ile Gly Tyr Thr His Met Lys Ile Ala Glu Gly
                 320                 325                 330

 Val Asn Ser Leu Leu Gln Met Ala Gly Leu Leu Ala Arg Leu Cys
                 335                 340                 345

 Gln Lys Thr Met Ala Pro Val Ala Ser
                 350

<210> 6080
<211> 1315
<212> DNA
<213> Homo sapien

<400> 6080
 cggggatttt gtgccccgat ctatagttcc ttgagtctcc acacacactc 50

 ctcacagaga tctgtagcgt aggtacgtga cagctctgcc tacatctgac 100

 gtccggagtc attaaccagg aatgtatgtg tgtctgtgtg tctctctgtg 150

 gagtcgtcag aattcttcat aggggttaag ctaaaaaagc gaggcgagga 200

 gcccctctcc aatggctcag ttttgctgaa taatcacgtg tgaatcgagg 250

 ggcgggcttt tggcaggcag atcttactag tatttactac caagctctac 300

 tccagattaa ccatcccagt ccttctgtca gtctccgatg ccatcatgca 350

 gcctggttag gagcaaagga aaggggaaaa agaaaaacga ctaattcatc 400

 ttttcctgat cgtcaggacc ctaaagaatg gccgagcctt gggggaacga 450

 gttggcgtcc gcagctgcca ggggggacct agagcaactt actagtttgt 500

 tgcaaaataa tgtaaacgtc aatgcacaaa atggatttgg aaggactgcg 550

 ctgcaggtta tgaaacttgg aaatcccgag attgccagga gactgctact 600

 tagaggtgct aatcccgatt tgaaagaccg aactggtttc gctgtcattc 650

 atgatgcggc cagagcaggt ttcctggaca ctttacagac tttgctggag 700

 tttcaagctg atgttaacat cgaggataat gaagggaacc tgcccttgca 750

 cttggctgcc aaagaaggcc acctccgggt ggtggagttc ctggtgaagc 800

 acacggccag caatgtgggg catcggaacc ataaggggga caccgcctgt 850

 gatttggcca ggctctatgg gaggaatgag gttgttagcc tgatgcaggc 900

 aaacggggct gggggagcca caaatcttca ataaacgtgg ggagggctcc 950

 cccacgttgc ctctacttta tcaattaact gagtagctct cctgactttt 1000

 aatgtcattt gttaaaatac agttctgtca tatgttaagc agctaaattt 1050

 tctgaaactg cataagtgaa aatcttacaa caggtttatg aatatattta 1100

 agcaacatct ttttaacctg caaaatctgt tctaacatgt aattgcagat 1150

 aactttgact ttcttctgaa tattttatct ttccttggct tttcccttgc 1200

 ttcccctttt gccaatctca acacccaagt tgaagacttt gtttttaaaa 1250

 tggtttgtcc tgatgctttt gtctaattaa aacactttca aaacaggaaa 1300

 aaaaaaaaaa aaaaa 1315

<210> 6081
<211> 168
<212> PRT
<213> Homo sapien

<400> 6081
 Met Ala Glu Pro Trp Gly Asn Glu Leu Ala Ser Ala Ala Ala Arg
   1               5                  10                  15

 Gly Asp Leu Glu Gln Leu Thr Ser Leu Leu Gln Asn Asn Val Asn
                  20                  25                  30

 Val Asn Ala Gln Asn Gly Phe Gly Arg Thr Ala Leu Gln Val Met
                  35                  40                  45

 Lys Leu Gly Asn Pro Glu Ile Ala Arg Arg Leu Leu Leu Arg Gly
                  50                  55                  60

 Ala Asn Pro Asp Leu Lys Asp Arg Thr Gly Phe Ala Val Ile His
                  65                  70                  75

 Asp Ala Ala Arg Ala Gly Phe Leu Asp Thr Leu Gln Thr Leu Leu
                  80                  85                  90

 Glu Phe Gln Ala Asp Val Asn Ile Glu Asp Asn Glu Gly Asn Leu
                  95                 100                 105

 Pro Leu His Leu Ala Ala Lys Glu Gly His Leu Arg Val Val Glu
                 110                 115                 120

 Phe Leu Val Lys His Thr Ala Ser Asn Val Gly His Arg Asn His
                 125                 130                 135

 Lys Gly Asp Thr Ala Cys Asp Leu Ala Arg Leu Tyr Gly Arg Asn
                 140                 145                 150

 Glu Val Val Ser Leu Met Gln Ala Asn Gly Ala Gly Gly Ala Thr
                 155                 160                 165

 Asn Leu Gln


<210> 6082
<211> 2869
<212> DNA
<213> Homo sapien

<400> 6082
 cacgaagcag ggaaagggat ctggtaaaac ctaaatatga cctggataga 50

 acagatccat tagaaaataa ttatactcca gtctcttcgg tacctagtat 100

 ttcatctggc cactaccctg tacctacttt gagcagcact attacagtaa 150

 ttgctcctac tcatcatgga aacaacacta ccgaaagttg gtctgaattt 200

 catgaagacc aagtggacca taactcttac gtaagaccac ccatgccaaa 250

 gaaacggtgt agagactatg atgaaaaggg tttttgtatg agaggagaca 300

 tgtgtccttt tgatcatgga agtgatccag tagttgtaga agatgtgaat 350

 cttcctggta tgctgccttt cccagcacag cctcctgttg ttgaaggacc 400

 acctcctcct ggactccccc cacctccacc aattcttaca cccccacctg 450

 tgaatctcag gcccccagta ccaccgccag gtccattgcc acccagtctc 500

 ccacctgtta cagatgatat ttcttattct ttggttttga caggaccacc 550

 acctccactt ccagacctat gtatagacac agagtgcatg cacaaaggcc 600

 caacttgata ggactaacat caggggatat ggatttgcca cccagagaaa 650

 agcctcccaa taaaagcagt atgaggatag tagtggactc agaatcaagg 700

 aaaagaacca ttggttctgg agagcctgga gttcctacaa agaagacttg 750

 gtttgataaa ccaaatttta atagaacaaa cagcccaggc tttcagaaga 800

 aggttcaatt tggaaatgaa aataccaagc ttgaacttag aaaagttcct 850

 ccagaattaa ataatatcag caaacttaat gaacatttta gtcgatttgg 900

 aaccttggtt aacttacagg ttgcttataa tggtgatcct gaaggtgccc 950

 taatccaatt tgcaacatac gaagaagcaa agaaagcaat atcaagtacg 1000

 gaagcagtat taaacaatcg ctttattaag gtttattggc acagagaagg 1050

 aagcacccaa cagttacaaa ctacttctcc aaagccttta gtccagcagc 1100

 ccattttgcc tgttgtgaag cagtcagtca aagagcggct gggtccagta 1150

 ccttcaagta ctattgaacc tgcagaagcc cagagtgcct cttcagacct 1200

 tcctcaggtg ttgtctacat ctactggcct aacaaaaaca gtgtataatc 1250

 cagctgcttt gaaggctgca caggaaacct tacttgtttc cacctctgca 1300

 gttgataata atgaagcaca gaaaaaaaaa caggaggcat tgaaacttca 1350

 gcaggatgta aggaaaagga aacaagaaat tttagaaaag cacattgaaa 1400

 cacagaagat gttaatttca aaactggaga aaaacaaaac aatgaagtct 1450

 gaagataaag cagaaataat gaaaacttta gaggttttga caaaaaatat 1500

 taccaagttg aaagatgagg tcaaagctgc ttctcctgga cgctgtcttc 1550

 caaaaagtat aaaaaccaag actcagatgc agaaggaatt acttgacaca 1600

 gaactggatt tatataagaa gatgcaggct ggagaagaag tcactgaact 1650

 taggagaaag tatacagaat tacagctgga agctgccaaa cgagggattc 1700

 tttcatctgg tcggggcaga ggaattcatt caagaggtcg aggtgcagtt 1750

 catggccgag gcagggggcg agggcgaggg cgaggtgtgc ctggtcatgc 1800

 tgtggtggat caccgtccca gggcattgga gatttctgca tttacgggga 1850

 gcgatagaga agatcttctt cctcattttg cgcaatatgg tgaaattgaa 1900

 gattgtcaga ttgatgattc ctcacttcat gcagtaatta cattcaagac 1950

 aagagcagaa gctgaagcag ctgcagttca tggagctcgt ttcaaagggc 2000

 aagatctaaa actggcatgg aataaaccag taactaatat ttcagctgtt 2050

 gaaacagaag aagttgagcc tgatgaagaa gaatttcagg aagagtcttt 2100

 ggtggatgac tcattacttc aagatgatga tgaagaagaa gaggacaatg 2150

 aatctcgttc ttggagaaga tgatttgact gatcattgat ctgcatatgc 2200

 tagaactcta cctgtgtttc attagtatta tctaatgtac ttttacatat 2250

 ttgtaaaaac aatttttggt aaaatgtgat gaagatggat ttcacaaata 2300

 gacaaaaaag aagaaaacta ccttctgatc ttgtattttg aaagattgat 2350

 gtttgcattt tacttcagta aacaattgct aaagacatca cactagaaac 2400

 atatgcaatg tttttattac atacttctac tggacatcac agaattcttt 2450

 gggttctttg taatttaatg aataggtctg aaaacttatg accaatactt 2500

 gttataactt agaggacttt gttttattcc aaataaggaa tgaatttgca 2550

 tttaaaatct taatgaatgt tttcaaaact gaatagataa catagtactc 2600

 taactaaagt ctccaagtta tgtattataa tattacatag tagtatgctt 2650

 aggctttact atgtattagc cttttgttgg actgtgtatg tattttacca 2700

 tatgggtttt aatgataatg gtgtatgact gctttacatg agtccttatg 2750

 catccagatg ttataataaa gtggaatggt ctctttaaaa aaaaaaaagg 2800

 aaagaaaaga gaaaagcaat gacaaaaaaa aaaaaaaaaa aaaaaagcca 2850

 agacaatgtt ccttgattt 2869

<210> 6083
<211> 534
<212> PRT
<213> Homo sapien

<400> 6083
 Met Tyr Arg His Arg Val His Ala Gln Arg Pro Asn Leu Ile Gly
   1               5                  10                  15

 Leu Thr Ser Gly Asp Met Asp Leu Pro Pro Arg Glu Lys Pro Pro
                  20                  25                  30

 Asn Lys Ser Ser Met Arg Ile Val Val Asp Ser Glu Ser Arg Lys
                  35                  40                  45

 Arg Thr Ile Gly Ser Gly Glu Pro Gly Val Pro Thr Lys Lys Thr
                  50                  55                  60

 Trp Phe Asp Lys Pro Asn Phe Asn Arg Thr Asn Ser Pro Gly Phe
                  65                  70                  75

 Gln Lys Lys Val Gln Phe Gly Asn Glu Asn Thr Lys Leu Glu Leu
                  80                  85                  90

 Arg Lys Val Pro Pro Glu Leu Asn Asn Ile Ser Lys Leu Asn Glu
                  95                 100                 105

 His Phe Ser Arg Phe Gly Thr Leu Val Asn Leu Gln Val Ala Tyr
                 110                 115                 120

 Asn Gly Asp Pro Glu Gly Ala Leu Ile Gln Phe Ala Thr Tyr Glu
                 125                 130                 135

 Glu Ala Lys Lys Ala Ile Ser Ser Thr Glu Ala Val Leu Asn Asn
                 140                 145                 150

 Arg Phe Ile Lys Val Tyr Trp His Arg Glu Gly Ser Thr Gln Gln
                 155                 160                 165

 Leu Gln Thr Thr Ser Pro Lys Pro Leu Val Gln Gln Pro Ile Leu
                 170                 175                 180

 Pro Val Val Lys Gln Ser Val Lys Glu Arg Leu Gly Pro Val Pro
                 185                 190                 195

 Ser Ser Thr Ile Glu Pro Ala Glu Ala Gln Ser Ala Ser Ser Asp
                 200                 205                 210

 Leu Pro Gln Val Leu Ser Thr Ser Thr Gly Leu Thr Lys Thr Val
                 215                 220                 225

 Tyr Asn Pro Ala Ala Leu Lys Ala Ala Gln Glu Thr Leu Leu Val
                 230                 235                 240

 Ser Thr Ser Ala Val Asp Asn Asn Glu Ala Gln Lys Lys Lys Gln
                 245                 250                 255

 Glu Ala Leu Lys Leu Gln Gln Asp Val Arg Lys Arg Lys Gln Glu
                 260                 265                 270

 Ile Leu Glu Lys His Ile Glu Thr Gln Lys Met Leu Ile Ser Lys
                 275                 280                 285

 Leu Glu Lys Asn Lys Thr Met Lys Ser Glu Asp Lys Ala Glu Ile
                 290                 295                 300

 Met Lys Thr Leu Glu Val Leu Thr Lys Asn Ile Thr Lys Leu Lys
                 305                 310                 315

 Asp Glu Val Lys Ala Ala Ser Pro Gly Arg Cys Leu Pro Lys Ser
                 320                 325                 330

 Ile Lys Thr Lys Thr Gln Met Gln Lys Glu Leu Leu Asp Thr Glu
                 335                 340                 345

 Leu Asp Leu Tyr Lys Lys Met Gln Ala Gly Glu Glu Val Thr Glu
                 350                 355                 360

 Leu Arg Arg Lys Tyr Thr Glu Leu Gln Leu Glu Ala Ala Lys Arg
                 365                 370                 375

 Gly Ile Leu Ser Ser Gly Arg Gly Arg Gly Ile His Ser Arg Gly
                 380                 385                 390

 Arg Gly Ala Val His Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg
                 395                 400                 405

 Gly Val Pro Gly His Ala Val Val Asp His Arg Pro Arg Ala Leu
                 410                 415                 420

 Glu Ile Ser Ala Phe Thr Gly Ser Asp Arg Glu Asp Leu Leu Pro
                 425                 430                 435

 His Phe Ala Gln Tyr Gly Glu Ile Glu Asp Cys Gln Ile Asp Asp
                 440                 445                 450

 Ser Ser Leu His Ala Val Ile Thr Phe Lys Thr Arg Ala Glu Ala
                 455                 460                 465

 Glu Ala Ala Ala Val His Gly Ala Arg Phe Lys Gly Gln Asp Leu
                 470                 475                 480

 Lys Leu Ala Trp Asn Lys Pro Val Thr Asn Ile Ser Ala Val Glu
                 485                 490                 495

 Thr Glu Glu Val Glu Pro Asp Glu Glu Glu Phe Gln Glu Glu Ser
                 500                 505                 510

 Leu Val Asp Asp Ser Leu Leu Gln Asp Asp Asp Glu Glu Glu Glu
                 515                 520                 525

 Asp Asn Glu Ser Arg Ser Trp Arg Arg
                 530

<210> 6084
<211> 599
<212> DNA
<213> Homo sapien

<400> 6084
 aggccgcgct cgcgccgagg ggctgcgaga gtgaccgcgg ctgctccagc 50

 gctgacgccg agccatggcg gacgaggagc ttgaggcgct gaggagacag 100

 aggctggccg agctgcaggc caaacacggg gatcctggtg atgcggccca 150

 acaggaagca aagcacaggg aagcagaaat gagaaacagt atcttagccc 200

 aagttctgga tcagtcggcc cgggccaggt taagtaactt agcacttgta 250

 aagcctgaaa aaactaaagc agtagagaat taccttatac agatggcaag 300

 atatggacaa ctaagtgaga aggtatcaga acaaggttta atagaaatcc 350

 ttaaaaaagt aagccaacaa acagaaaaga caacaacagt gaaattcaac 400

 agaagaaaag taatggactc tgatgaagat gacgattatt gaactacaag 450

 tgctcacaga ctagaactta acggaacaag tctaggacag aagttaagat 500

 ctgattattt actttgttta ttgtctatat gccttttaaa aaaataaact 550

 tgttatgcaa aataaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 599

<210> 6085
<211> 125
<212> PRT
<213> Homo sapien

<400> 6085
 Met Ala Asp Glu Glu Leu Glu Ala Leu Arg Arg Gln Arg Leu Ala
   1               5                  10                  15

 Glu Leu Gln Ala Lys His Gly Asp Pro Gly Asp Ala Ala Gln Gln
                  20                  25                  30

 Glu Ala Lys His Arg Glu Ala Glu Met Arg Asn Ser Ile Leu Ala
                  35                  40                  45

 Gln Val Leu Asp Gln Ser Ala Arg Ala Arg Leu Ser Asn Leu Ala
                  50                  55                  60

 Leu Val Lys Pro Glu Lys Thr Lys Ala Val Glu Asn Tyr Leu Ile
                  65                  70                  75

 Gln Met Ala Arg Tyr Gly Gln Leu Ser Glu Lys Val Ser Glu Gln
                  80                  85                  90

 Gly Leu Ile Glu Ile Leu Lys Lys Val Ser Gln Gln Thr Glu Lys
                  95                 100                 105

 Thr Thr Thr Val Lys Phe Asn Arg Arg Lys Val Met Asp Ser Asp
                 110                 115                 120

 Glu Asp Asp Asp Tyr
                 125

<210> 6086
<211> 1611
<212> DNA
<213> Homo sapien

<400> 6086
 acataatttc tggagccctg taccaacgtg tggccacata ttctgtcagg 50

 aaccctgtgt gatcatggtc tggatctgca acacgggcca ggccaaagtc 100

 acagatcttg agatcacagg tggtgttgag cagcaggcag gcaggcaatc 150

 ggtccgagtg gctgtcggct cttcagctct ccgctcggcg tcttccttcc 200

 tctcccggtc agcgtcggcg gctgcaccgg cggcgggcag tcctgcggga 250

 ggggcgacaa gagctgaggc gcggccgccg agcgtcgagc tcagcgcggc 300

 ggaggcggcg gcggcccggc agccaacatg gcggcggcgg cggcggcggg 350

 cgcgggcccg gagatggtcc gcgggcaggt gttcgacgtg gggccgcgct 400

 acaccaacct ctcgtacatc ggcgagggcg cctacggcat ggtgtgctct 450

 gcttatgata atgtcaacaa agttcgagta gctatcaaga aaatcagccc 500

 ctttgagcac cagacctact gccagagaac cctgagggag ataaaaatct 550

 tactgcgctt cagacatgag aacatcattg gaatcaatga cattattcga 600

 gcaccaacca tcgagcaaat gaaagatgta tatatagtac aggacctcat 650

 ggaaacagat ctttacaagc tcttgaagac acaacacctc agcaatgacc 700

 atatctgcta ttttctctac cagatcctca gagggttaaa atatatccat 750

 tcagctaacg ttctgcaccg tgacctcaag ccttccaacc tgctgctcaa 800

 caccacctgt gatctcaaga tctgtgactt tggcctggcc cgtgttgcag 850

 atccagacca tgatcacaca gggttcctga cagaatatgt ggccacacgt 900

 tggtacaggg ctccagaaat tatgttgaat tccaagggct acaccaagtc 950

 cattgatatt tggtctgtag gctgcattct ggcagaaatg ctttccaaca 1000

 ggcccatctt tccagggaag cattatcttg accagctgaa tcacattttg 1050

 ggtattcttg gatccccatc acaagaagac ctgaattgta taataaattt 1100

 aaaagctagg aactatttgc tttctcttcc acacaaaaat aaggtgccat 1150

 ggaacaggct gttcccaaat gctgactcca aagctctgga cttattggac 1200

 aaaatgttga cattcaaccc acacaagagg attgaagtag aacaggctct 1250

 ggcccaccca tatctggagc agtattacga cccgagtgac gagcccatcg 1300

 ccgaagcacc attcaagttc gacatggaat tggatgactt gcctaaggaa 1350

 aagctaaaag aactaatttt tgaagagact gctagattcc agccaggata 1400

 cagatcttaa atttgtcagg acaagggctc agaggactgg acgtgctcag 1450

 acatcggtgt tcttcttccc agttcttgac ccctggtcct gtctccagcc 1500

 cgtcttggct tatccacttt gactcctttg agccgtttgg aggggcggtt 1550

 tctggtagtt gtggctttta tgctttcaaa gaatttcttc agtccagaga 1600

 attcactggc c 1611

<210> 6087
<211> 360
<212> PRT
<213> Homo sapien

<400> 6087
 Met Ala Ala Ala Ala Ala Ala Gly Ala Gly Pro Glu Met Val Arg
   1               5                  10                  15

 Gly Gln Val Phe Asp Val Gly Pro Arg Tyr Thr Asn Leu Ser Tyr
                  20                  25                  30

 Ile Gly Glu Gly Ala Tyr Gly Met Val Cys Ser Ala Tyr Asp Asn
                  35                  40                  45

 Val Asn Lys Val Arg Val Ala Ile Lys Lys Ile Ser Pro Phe Glu
                  50                  55                  60

 His Gln Thr Tyr Cys Gln Arg Thr Leu Arg Glu Ile Lys Ile Leu
                  65                  70                  75

 Leu Arg Phe Arg His Glu Asn Ile Ile Gly Ile Asn Asp Ile Ile
                  80                  85                  90

 Arg Ala Pro Thr Ile Glu Gln Met Lys Asp Val Tyr Ile Val Gln
                  95                 100                 105

 Asp Leu Met Glu Thr Asp Leu Tyr Lys Leu Leu Lys Thr Gln His
                 110                 115                 120

 Leu Ser Asn Asp His Ile Cys Tyr Phe Leu Tyr Gln Ile Leu Arg
                 125                 130                 135

 Gly Leu Lys Tyr Ile His Ser Ala Asn Val Leu His Arg Asp Leu
                 140                 145                 150

 Lys Pro Ser Asn Leu Leu Leu Asn Thr Thr Cys Asp Leu Lys Ile
                 155                 160                 165

 Cys Asp Phe Gly Leu Ala Arg Val Ala Asp Pro Asp His Asp His
                 170                 175                 180

 Thr Gly Phe Leu Thr Glu Tyr Val Ala Thr Arg Trp Tyr Arg Ala
                 185                 190                 195

 Pro Glu Ile Met Leu Asn Ser Lys Gly Tyr Thr Lys Ser Ile Asp
                 200                 205                 210

 Ile Trp Ser Val Gly Cys Ile Leu Ala Glu Met Leu Ser Asn Arg
                 215                 220                 225

 Pro Ile Phe Pro Gly Lys His Tyr Leu Asp Gln Leu Asn His Ile
                 230                 235                 240

 Leu Gly Ile Leu Gly Ser Pro Ser Gln Glu Asp Leu Asn Cys Ile
                 245                 250                 255

 Ile Asn Leu Lys Ala Arg Asn Tyr Leu Leu Ser Leu Pro His Lys
                 260                 265                 270

 Asn Lys Val Pro Trp Asn Arg Leu Phe Pro Asn Ala Asp Ser Lys
                 275                 280                 285

 Ala Leu Asp Leu Leu Asp Lys Met Leu Thr Phe Asn Pro His Lys
                 290                 295                 300

 Arg Ile Glu Val Glu Gln Ala Leu Ala His Pro Tyr Leu Glu Gln
                 305                 310                 315

 Tyr Tyr Asp Pro Ser Asp Glu Pro Ile Ala Glu Ala Pro Phe Lys
                 320                 325                 330

 Phe Asp Met Glu Leu Asp Asp Leu Pro Lys Glu Lys Leu Lys Glu
                 335                 340                 345

 Leu Ile Phe Glu Glu Thr Ala Arg Phe Gln Pro Gly Tyr Arg Ser
                 350                 355                 360

<210> 6088
<211> 1940
<212> DNA
<213> Homo sapien

<400> 6088
 acccagggtc cggcctgcgc cttcccgcca ggcctggaca ctggttcaac 50

 acctgtgact tcatgtgtgc gcgccggcca cacctgcagt cacacctgta 100

 gccccctctg ccaagagatc cataccgagg cagcgtcggt ggctacaagc 150

 cctcagtcca cacctgtgga cacctgtgac acctggccac acgacctgtg 200

 gccgcggcct ggcgtctgct gcgacaggag cccttacctc ccctgttata 250

 acacctgaca gccacctaac tgcccctgca gaaggagcaa tggccttggc 300

 tcctgagagg taagagcccg gcccaccctc tccagatgcc agtccccgag 350

 cgccctgcag ccggccctga ctctccgcgg ccgggcaccc gcagggcagc 400

 cccacgcgtg ctgttcggag agtggctcct tggagagatc agcagcggct 450

 gctatgaggg gctgcagtgg ctggacgagg cccgcacctg tttccgcgtg 500

 ccctggaagc acttcgcgcg caaggacctg agcgaggccg acgcgcgcat 550

 cttcaaggcc tgggctgtgg cccgcggcag gtggccgcct agcagcaggg 600

 gaggtggccc gccccccgag gctgagactg cggagcgcgc cggctggaaa 650

 accaacttcc gctgcgcact gcgcagcacg cgtcgcttcg tgatgctgcg 700

 agataactcg ggggacccgg ccgacccgca caaggtgtac gcgctcagcc 750

 gggagctgtg ctggcgagaa ggcccaggca cggaccagac tgaggcagag 800

 gcccccgcag ctgtcccacc accacagggt gggcccccag ggccattcct 850

 ggcacacaca catgctggac tccaagcccc aggccccctc cctgccccag 900

 ctggtgacga gggggacctc ctgctccagg cagtgcaaca gagctgcctg 950

 gcagaccatc tgctgacagc gtcatggggg gcagatccag tcccaaccaa 1000

 ggctcctgga gagggacaag aagggcttcc cctgactggg gcctgtgctg 1050

 gaggcccagg gctccctgct ggggagctgt acgggtgggc agtagagacg 1100

 acccccagcc ccgggcccca gcccgcggca ctaacgacag gcgaggccgc 1150

 ggccccagag tccccgcacc aggcagagcc gtacctgtca ccctccccaa 1200

 gcgcctgcac cgcggtgcaa gagcccagcc caggggcgct ggacgtgacc 1250

 atcatgtaca agggccgcac ggtgctgcag aaggtggtgg gacacccgag 1300

 ctgcacgttc ctatacggcc ccccagaccc agctgtccgg gccacagacc 1350

 cccagcaggt agcattcccc agccctgccg agctcccgga ccagaagcag 1400

 ctgcgctaca cggaggaact gctgcggcac gtggcccctg ggttgcacct 1450

 ggagcttcgg gggccacagc tgtgggcccg gcgcatgggc aagtgcaagg 1500

 tgtactggga ggtgggcggc cccccaggct ccgccagccc ctccacccca 1550

 gcctgcctgc tgcctcggaa ctgtgacacc cccatcttcg acttcagagt 1600

 cttcttccga gagctggtgg aattccgggc acggcagcgc cgtggctccc 1650

 cacgctatac catctacctg ggcttcgggc aggacctgtc agctgggagg 1700

 cccaaggaga agagcctggt cctggtgaag ctggaaccct ggctgtgccg 1750

 agtgcaccta gagggcacgc agcgtgaggg tgtgtcttcc ctggatagca 1800

 gcagcctcag cctctgcctg tccagcgcca acagcctcta tgacgacatc 1850

 gagtgcttcc ttatggagct ggagcagccc gcctagaacc cagtctaatg 1900

 agaactccag aaagctggag cagcccacct agagctggcc 1940

<210> 6089
<211> 516
<212> PRT
<213> Homo sapien

<400> 6089
 Met Pro Val Pro Glu Arg Pro Ala Ala Gly Pro Asp Ser Pro Arg
   1               5                  10                  15

 Pro Gly Thr Arg Arg Ala Ala Pro Arg Val Leu Phe Gly Glu Trp
                  20                  25                  30

 Leu Leu Gly Glu Ile Ser Ser Gly Cys Tyr Glu Gly Leu Gln Trp
                  35                  40                  45

 Leu Asp Glu Ala Arg Thr Cys Phe Arg Val Pro Trp Lys His Phe
                  50                  55                  60

 Ala Arg Lys Asp Leu Ser Glu Ala Asp Ala Arg Ile Phe Lys Ala
                  65                  70                  75

 Trp Ala Val Ala Arg Gly Arg Trp Pro Pro Ser Ser Arg Gly Gly
                  80                  85                  90

 Gly Pro Pro Pro Glu Ala Glu Thr Ala Glu Arg Ala Gly Trp Lys
                  95                 100                 105

 Thr Asn Phe Arg Cys Ala Leu Arg Ser Thr Arg Arg Phe Val Met
                 110                 115                 120

 Leu Arg Asp Asn Ser Gly Asp Pro Ala Asp Pro His Lys Val Tyr
                 125                 130                 135

 Ala Leu Ser Arg Glu Leu Cys Trp Arg Glu Gly Pro Gly Thr Asp
                 140                 145                 150

 Gln Thr Glu Ala Glu Ala Pro Ala Ala Val Pro Pro Pro Gln Gly
                 155                 160                 165

 Gly Pro Pro Gly Pro Phe Leu Ala His Thr His Ala Gly Leu Gln
                 170                 175                 180

 Ala Pro Gly Pro Leu Pro Ala Pro Ala Gly Asp Glu Gly Asp Leu
                 185                 190                 195

 Leu Leu Gln Ala Val Gln Gln Ser Cys Leu Ala Asp His Leu Leu
                 200                 205                 210

 Thr Ala Ser Trp Gly Ala Asp Pro Val Pro Thr Lys Ala Pro Gly
                 215                 220                 225

 Glu Gly Gln Glu Gly Leu Pro Leu Thr Gly Ala Cys Ala Gly Gly
                 230                 235                 240

 Pro Gly Leu Pro Ala Gly Glu Leu Tyr Gly Trp Ala Val Glu Thr
                 245                 250                 255

 Thr Pro Ser Pro Gly Pro Gln Pro Ala Ala Leu Thr Thr Gly Glu
                 260                 265                 270

 Ala Ala Ala Pro Glu Ser Pro His Gln Ala Glu Pro Tyr Leu Ser
                 275                 280                 285

 Pro Ser Pro Ser Ala Cys Thr Ala Val Gln Glu Pro Ser Pro Gly
                 290                 295                 300

 Ala Leu Asp Val Thr Ile Met Tyr Lys Gly Arg Thr Val Leu Gln
                 305                 310                 315

 Lys Val Val Gly His Pro Ser Cys Thr Phe Leu Tyr Gly Pro Pro
                 320                 325                 330

 Asp Pro Ala Val Arg Ala Thr Asp Pro Gln Gln Val Ala Phe Pro
                 335                 340                 345

 Ser Pro Ala Glu Leu Pro Asp Gln Lys Gln Leu Arg Tyr Thr Glu
                 350                 355                 360

 Glu Leu Leu Arg His Val Ala Pro Gly Leu His Leu Glu Leu Arg
                 365                 370                 375

 Gly Pro Gln Leu Trp Ala Arg Arg Met Gly Lys Cys Lys Val Tyr
                 380                 385                 390

 Trp Glu Val Gly Gly Pro Pro Gly Ser Ala Ser Pro Ser Thr Pro
                 395                 400                 405

 Ala Cys Leu Leu Pro Arg Asn Cys Asp Thr Pro Ile Phe Asp Phe
                 410                 415                 420

 Arg Val Phe Phe Arg Glu Leu Val Glu Phe Arg Ala Arg Gln Arg
                 425                 430                 435

 Arg Gly Ser Pro Arg Tyr Thr Ile Tyr Leu Gly Phe Gly Gln Asp
                 440                 445                 450

 Leu Ser Ala Gly Arg Pro Lys Glu Lys Ser Leu Val Leu Val Lys
                 455                 460                 465

 Leu Glu Pro Trp Leu Cys Arg Val His Leu Glu Gly Thr Gln Arg
                 470                 475                 480

 Glu Gly Val Ser Ser Leu Asp Ser Ser Ser Leu Ser Leu Cys Leu
                 485                 490                 495

 Ser Ser Ala Asn Ser Leu Tyr Asp Asp Ile Glu Cys Phe Leu Met
                 500                 505                 510

 Glu Leu Glu Gln Pro Ala
                 515

<210> 6090
<211> 3568
<212> DNA
<213> Homo sapien

<400> 6090
 ccggtcctga gacacgctgt gtggctgaaa agtgaaggca agagctcatt 50

 tggcctctgt gctcccctcc gcaagggatc gtttctccag aagagctgga 100

 tattctttcg cccagttatg gcagacaagt taacgagaat tgctattgtc 150

 aaccatgaca aatgtaaacc taagaaatgt cgacaggaat gcaaaaagag 200

 ttgtcctgta gttcgaatgg gaaaattatg catagaggtt acaccccaga 250

 gcaaaatagc atggatttcc gaaactcttt gtattggttg tggtatctgt 300

 attaagaaat gcccctttgg cgccttatca attgtcaatc taccaagcaa 350

 cttggaaaaa gaaaccacac atcgatattg tgccaatgcc ttcaaacttc 400

 acaggttgcc tatccctcgt ccaggtgaag ttttgggatt agttggaact 450

 aatggtattg gaaagtcagc tgctttaaaa attttagcag gaaaacaaaa 500

 gccaaacctt ggaaagtacg atgatcctcc tgactggcag gagattttga 550

 cttatttccg tggatctgaa ttacaaaatt actttacaaa gattctagaa 600

 gatgacctaa aagccatcat caaacctcaa tatgtagcca gattcctaag 650

 gctggcaaag gggacagtgg gatctatttt ggaccgaaaa gatgaaacaa 700

 agacacaggc aattgtatgt cagcagcttg atttaaccca cctaaaagaa 750

 cgaaatgttg aagatctttc aggaggagag ttgcagagat ttgcttgtgc 800

 tgtcgtttgc atacagaaag ctgatatttt catgtttgat gagccttcta 850

 gttacctaga tgtcaagcag cgtttaaagg ctgctattac tatacgatct 900

 ctaataaatc cagatagata tatcattgtg gtggaacatg atctaagtgt 950

 attagactat ctctccgact tcatctgctg tttatatggt gtaccaagcg 1000

 cctatggagt tgtcactatg ccttttagtg taagagaagg cataaacatt 1050

 tttttggatg gctatgttcc aacagaaaac ttgagattca gagatgcatc 1100

 acttgttttt aaagtggctg agacagcaaa tgaagaagaa gttaaaaaga 1150

 tgtgtatgta taaatatcca ggaatgaaga aaaaaatggg agaatttgag 1200

 ctagcaattg tagctggaga gtttacagat tctgaaatta tggtgatgct 1250

 gggggaaaat ggaacgggta aaacgacatt tatcagaatg cttgctggaa 1300

 gacttaaacc tgatgaagga ggagaagtac cagttctaaa tgtcagttat 1350

 aagccacaga aaattagtcc caaatcaact ggaagtgttc gccagttact 1400

 acatgaaaag ataagagatg cttatactca cccacaattt gtgaccgatg 1450

 taatgaagcc tctgcaaatt gaaaacatca ttgatcaaga ggtgcagaca 1500

 ttatctggtg gtgaactaca gcgagtacgt ttacgccttt gcttgggcaa 1550

 acctgctgat gtctatttaa ttgatgaacc atctgcatat ttggattctg 1600

 agcaaagact gatggcagct cgagttgtca aacgtttcat actccatgca 1650

 aaaaagacag cctttgttgt ggaacatgac ttcatcatgg ccacctatct 1700

 agcggatcgc gtcatcgttt ttgatggtgt tccatctaag aacacagttg 1750

 caaacagtcc tcaaaccctt ttggctggca tgaataaatt tttgtctcag 1800

 cttgaaatta cattcagaag agatccaaac aactataggc cacgaataaa 1850

 caaacttaat tcaattaagg atgtagaaca aaagaagagt ggaaactact 1900

 ttttcttgga tgattagact gactctgaga atattgataa gccatttatt 1950

 aaaaggagta tttactagaa ttttttgtca tataaaactt gaatcaggat 2000

 tttatgcccc acatactctg gaacttgaag tataatatac ttaatataac 2050

 ataaaaagcc agttgggttc taaattgtag ttgaaacaca gaaaatgcca 2100

 cttttctgtt cctgaagagg ctcttttgtg cataatattc taaaatgaag 2150

 acatttcaag ctatacaaat tacttccaag ttttcatgat gtatgggaag 2200

 attttcagta ggtgtattat attcacggta ccaaatgctg accagtgttg 2250

 ctccattttt taaatcttga aaagggtttc tgtacttacc tggtttgcca 2300

 agtatgccag tgtaatgaaa ctgcccttat tttaaaagcc agtcaaagat 2350

 tccactgatt gacatttgat aaataaacat caggattatg tttattgttt 2400

 gttttcagtc tttgcactat attaccagta tatggtttcc gaggaagatt 2450

 atctactgca aaacaccact gttggaaaaa taggtatttt taaattgttt 2500

 ttaatccttt tttggtgctt ttaaacatgt ttaagcaaaa accaattcag 2550

 tccattcccc gcaaaaaacc cctaacttta ctctgaactt tttttgtttt 2600

 tgcattccat gaggttctgt attcagtcat tctctaggta atgtcatttt 2650

 tgtacacata tatttatata atcactgatt gagatttagg aaaaagcatt 2700

 tctaaagaat atttgcttcc cttagaacta cagactcgaa atctttaaag 2750

 atggtgccta agcatctatg tatttttttt aagttccaca gatttttctg 2800

 ttgggcaggc caaggattat aaaccacttc cctaaaggca acattaatgc 2850

 aaaagtcccc agatggcaat acaaagtatc ccctggtacc acatatattc 2900

 atttgtgagt ttggatatag agcacattat ctaaaccatt ttgtagttcc 2950

 aaaaacccat ctaaatttct tgagttcctg aattttgaac aggattacct 3000

 ggagcctgga gccactttaa gttgtacttc tgactaaact ggaattatga 3050

 gtgaggaaga gtgtttacta aataaatgac tggggcaagc aaaattgagg 3100

 aggaaattag aaactgtttg acaaacttta agagctactt gaaataacag 3150

 aagtcttgat taatatgcaa ataatggcta gaaagtatgg tttaactgga 3200

 ccctattatg ccttttaaaa ataatttcag taacccataa atacatgttg 3250

 taaaaaattc aaatatacag aatggaataa aaaaatgatc tccctttatt 3300

 accctcccaa aggttaccag cgtttgaatt taataatgta tattctttca 3350

 tgcttttttc tgtgcactta cctaagtgtg aatatgtaaa gggtttgttt 3400

 tgtatacaaa tgggattata ctaaaataag taatgcctat ttttaaggat 3450

 aggttaaatt tgtgaatgat catttcaaat atattgaata aaataagcaa 3500

 aagctattgt tatttactga tcctgaaaaa aaaaaaaaaa aaaaaaaaaa 3550

 aaaaaaaaaa aaaaaaaa 3568

<210> 6091
<211> 599
<212> PRT
<213> Homo sapien

<400> 6091
 Met Ala Asp Lys Leu Thr Arg Ile Ala Ile Val Asn His Asp Lys
   1               5                  10                  15

 Cys Lys Pro Lys Lys Cys Arg Gln Glu Cys Lys Lys Ser Cys Pro
                  20                  25                  30

 Val Val Arg Met Gly Lys Leu Cys Ile Glu Val Thr Pro Gln Ser
                  35                  40                  45

 Lys Ile Ala Trp Ile Ser Glu Thr Leu Cys Ile Gly Cys Gly Ile
                  50                  55                  60

 Cys Ile Lys Lys Cys Pro Phe Gly Ala Leu Ser Ile Val Asn Leu
                  65                  70                  75

 Pro Ser Asn Leu Glu Lys Glu Thr Thr His Arg Tyr Cys Ala Asn
                  80                  85                  90

 Ala Phe Lys Leu His Arg Leu Pro Ile Pro Arg Pro Gly Glu Val
                  95                 100                 105

 Leu Gly Leu Val Gly Thr Asn Gly Ile Gly Lys Ser Ala Ala Leu
                 110                 115                 120

 Lys Ile Leu Ala Gly Lys Gln Lys Pro Asn Leu Gly Lys Tyr Asp
                 125                 130                 135

 Asp Pro Pro Asp Trp Gln Glu Ile Leu Thr Tyr Phe Arg Gly Ser
                 140                 145                 150

 Glu Leu Gln Asn Tyr Phe Thr Lys Ile Leu Glu Asp Asp Leu Lys
                 155                 160                 165

 Ala Ile Ile Lys Pro Gln Tyr Val Ala Arg Phe Leu Arg Leu Ala
                 170                 175                 180

 Lys Gly Thr Val Gly Ser Ile Leu Asp Arg Lys Asp Glu Thr Lys
                 185                 190                 195

 Thr Gln Ala Ile Val Cys Gln Gln Leu Asp Leu Thr His Leu Lys
                 200                 205                 210

 Glu Arg Asn Val Glu Asp Leu Ser Gly Gly Glu Leu Gln Arg Phe
                 215                 220                 225

 Ala Cys Ala Val Val Cys Ile Gln Lys Ala Asp Ile Phe Met Phe
                 230                 235                 240

 Asp Glu Pro Ser Ser Tyr Leu Asp Val Lys Gln Arg Leu Lys Ala
                 245                 250                 255

 Ala Ile Thr Ile Arg Ser Leu Ile Asn Pro Asp Arg Tyr Ile Ile
                 260                 265                 270

 Val Val Glu His Asp Leu Ser Val Leu Asp Tyr Leu Ser Asp Phe
                 275                 280                 285

 Ile Cys Cys Leu Tyr Gly Val Pro Ser Ala Tyr Gly Val Val Thr
                 290                 295                 300

 Met Pro Phe Ser Val Arg Glu Gly Ile Asn Ile Phe Leu Asp Gly
                 305                 310                 315

 Tyr Val Pro Thr Glu Asn Leu Arg Phe Arg Asp Ala Ser Leu Val
                 320                 325                 330

 Phe Lys Val Ala Glu Thr Ala Asn Glu Glu Glu Val Lys Lys Met
                 335                 340                 345

 Cys Met Tyr Lys Tyr Pro Gly Met Lys Lys Lys Met Gly Glu Phe
                 350                 355                 360

 Glu Leu Ala Ile Val Ala Gly Glu Phe Thr Asp Ser Glu Ile Met
                 365                 370                 375

 Val Met Leu Gly Glu Asn Gly Thr Gly Lys Thr Thr Phe Ile Arg
                 380                 385                 390

 Met Leu Ala Gly Arg Leu Lys Pro Asp Glu Gly Gly Glu Val Pro
                 395                 400                 405

 Val Leu Asn Val Ser Tyr Lys Pro Gln Lys Ile Ser Pro Lys Ser
                 410                 415                 420

 Thr Gly Ser Val Arg Gln Leu Leu His Glu Lys Ile Arg Asp Ala
                 425                 430                 435

 Tyr Thr His Pro Gln Phe Val Thr Asp Val Met Lys Pro Leu Gln
                 440                 445                 450

 Ile Glu Asn Ile Ile Asp Gln Glu Val Gln Thr Leu Ser Gly Gly
                 455                 460                 465

 Glu Leu Gln Arg Val Arg Leu Arg Leu Cys Leu Gly Lys Pro Ala
                 470                 475                 480

 Asp Val Tyr Leu Ile Asp Glu Pro Ser Ala Tyr Leu Asp Ser Glu
                 485                 490                 495

 Gln Arg Leu Met Ala Ala Arg Val Val Lys Arg Phe Ile Leu His
                 500                 505                 510

 Ala Lys Lys Thr Ala Phe Val Val Glu His Asp Phe Ile Met Ala
                 515                 520                 525

 Thr Tyr Leu Ala Asp Arg Val Ile Val Phe Asp Gly Val Pro Ser
                 530                 535                 540

 Lys Asn Thr Val Ala Asn Ser Pro Gln Thr Leu Leu Ala Gly Met
                 545                 550                 555

 Asn Lys Phe Leu Ser Gln Leu Glu Ile Thr Phe Arg Arg Asp Pro
                 560                 565                 570

 Asn Asn Tyr Arg Pro Arg Ile Asn Lys Leu Asn Ser Ile Lys Asp
                 575                 580                 585

 Val Glu Gln Lys Lys Ser Gly Asn Tyr Phe Phe Leu Asp Asp
                 590                 595

<210> 6092
<211> 3169
<212> DNA
<213> Homo sapien

<400> 6092
 ccgcggacct gtcagagata cagaggttgt gggggcggga gacagaaaga 50

 gagagagatc cagagaccga gtcttacgtt gacacgcaga gagaaagacg 100

 cagagacaga caaacaaaca gataggagag gctctccagg aggccggggg 150

 gcccactccg cctatcgctc ccctcggcta cgctgccact tcaatgcccc 200

 gcaggtcgcg agctgctgtt ctttcgaagg cgtcggagaa ccaggggcgt 250

 cccgcgccac ctctgactcg gagcagcgcc gagcactgac gctcccgccc 300

 ttgggcaagg acgccagtgc gcccgcgcgc gtccctctgc gcggcagccc 350

 gtcgcgggcc ctcaagggga agcccaggcc aggatggccc cgggtcgcgc 400

 ggtggccggg ctcctgttgc tggcggccgc cggcctcgga ggagtggcgg 450

 aggggccagg gctagccttc agcgaggatg tgctgagcgt gttcggcgcg 500

 aatctgagcc tgtcggcggc gcagctccag cacttgctgg agcagatggg 550

 agccgcctcc cgcgtgggcg tcccggagcc tggccagctg cacttcaacc 600

 agtgtttaac tgctgaagag atcttttccc ttcatggctt ttcaaatgct 650

 acccaaataa ccagctccaa attctctgtc atctgtccag cagtcttaca 700

 gcaattgaac tttcacccat gtgaggatcg gcccaagcac aaaacaagac 750

 caagtcattc agaagtttgg ggatatggat tcctgtcagt gacgattatt 800

 aatctggcat ctctcctcgg attgattttg actccactga taaagaaatc 850

 ttatttccca aagattttga ccttttttgt ggggctggct attgggactc 900

 ttttttcaaa tgcaattttc caacttattc cagaggcatt tggatttgat 950

 cccaaagtcg acagttatgt tgagaaggca gttgctgtgt ttggtggatt 1000

 ttacctactt ttcttttttg aaagaatgct aaagatgtta ttaaagacat 1050

 atggtcagaa tggtcatacc cactttggaa atgataactt tggtcctcaa 1100

 gaaaaaactc atcaacctaa agcattacct gccatcaatg gtgtgacatg 1150

 ctatgcaaat cctgctgtca cagaagctaa tggacatatc cattttgata 1200

 atgtcagtgt ggtatctcta caggatggaa aaaaagagcc aagttcatgt 1250

 acctgtttga aggggcccaa actgtcagaa atagggacga ttgcctggat 1300

 gataacgctc tgcgatgccc tccacaattt catcgatggc ctggcgattg 1350

 gggcttcctg caccttgtct ctccttcagg gactcagtac ttccatagca 1400

 atcctatgtg aggagtttcc ccacgagtta ggagactttg tgatcctact 1450

 caatgcaggg atgagcactc gacaagcctt gctattcaac ttcctttctg 1500

 catgttcctg ctatgttggg ctagcttttg gcattttggt gggcaacaat 1550

 ttcgctccaa atattatatt tgcacttgct ggaggcatgt tcctctatat 1600

 ttctctggca gatatgtttc cagagatgaa tgatatgctg agagaaaagg 1650

 taactggaag aaaaaccgat ttcaccttct tcatgattca gaatgctgga 1700

 atgttaactg gattcacagc cattctactc attaccttgt atgcaggaga 1750

 aatcgaattg gagtaataga aaatggaaga tggtgttgtt aataaaggca 1800

 tttaatagat aaaaacatct ccaaaaagga ttttgaagct gatcctattt 1850

 agttaaaaag ataattttgc tttcaaccgt aggtccagaa aactaattat 1900

 tggcatcagt ctgtgaaata gtccattatt tgttgttaaa aatgcttcaa 1950

 aaggttttca gtgtcagtct gagatgcctg gtatatagga gcctttggga 2000

 aatacctatt tttcagtatt ccatgcatat tggatatcac catgaagcaa 2050

 gagacatgca ttctataatc atgtagacac tcagactcag gggaaaatac 2100

 aagttatatc ctgaaagcct ttaaaactct atggtaggat caaagattca 2150

 aatggtttca gagaggtttt atttcaatta atttgttcta gtgctttcaa 2200

 gagcaagtac atcaaaatgt agaaggtaaa atgtatgcaa cactaatata 2250

 aattattcca agtctttaag gagccaaaga aaaaaaagat ttctcacagc 2300

 tttttgttct gttttgtatt tcaattagga acttgcagta ttattttgaa 2350

 aaccattcta aaataatagg agttaggaaa taaataaagt tttgctagcc 2400

 ctgctaagtt caggcttaga ggcttatcgc taagtgtaaa cttcaccaga 2450

 ttccacgaaa agctggatag ctttttttct gacttatgtt gtggttgcac 2500

 ccctcacaaa tggcagaaca gtatgtaaag ctggtaacac ctcggtttca 2550

 gtgcaccatg tgtttgcttt gtgaaggtga agaatatgtt ggtttagaga 2600

 aagaaattgg atgtaatttt atgcaattta cttttaaaga caaacataac 2650

 tatttagcag agaatatttt aataaatgca aaacaacagc tggactgctg 2700

 tacatcaagg acagattaac tggaaaacat atgttcctta tgtgtgattg 2750

 agagccattc agaaaagact tcctttgtgt tcagcctata cttttccata 2800

 tggtatacct tgaaaaaaat tagcacacca tggttatttt tctacctttt 2850

 ataaaagaca gagcctgttt actcatttag aagatagaga aaattggtct 2900

 aaaattgaac atcctagatt cacactccca agtcacttaa ggtgatttga 2950

 tggtgaggaa aatgattgac aaagcccaac aatgatctca ggaattacat 3000

 tttccaacag accaaaaaat gttttcatgt agcagcaatg cagatttggt 3050

 gaatatttaa tatatatttt agtatgtatt tcactttatg actgacaatt 3100

 aaaaaatatt gtttggccaa atagtaaaca cccttttgaa accaaaaaaa 3150

 aaaaaaaaaa aaaaaaaaa 3169

<210> 6093
<211> 460
<212> PRT
<213> Homo sapien

<400> 6093
 Met Ala Pro Gly Arg Ala Val Ala Gly Leu Leu Leu Leu Ala Ala
   1               5                  10                  15

 Ala Gly Leu Gly Gly Val Ala Glu Gly Pro Gly Leu Ala Phe Ser
                  20                  25                  30

 Glu Asp Val Leu Ser Val Phe Gly Ala Asn Leu Ser Leu Ser Ala
                  35                  40                  45

 Ala Gln Leu Gln His Leu Leu Glu Gln Met Gly Ala Ala Ser Arg
                  50                  55                  60

 Val Gly Val Pro Glu Pro Gly Gln Leu His Phe Asn Gln Cys Leu
                  65                  70                  75

 Thr Ala Glu Glu Ile Phe Ser Leu His Gly Phe Ser Asn Ala Thr
                  80                  85                  90

 Gln Ile Thr Ser Ser Lys Phe Ser Val Ile Cys Pro Ala Val Leu
                  95                 100                 105

 Gln Gln Leu Asn Phe His Pro Cys Glu Asp Arg Pro Lys His Lys
                 110                 115                 120

 Thr Arg Pro Ser His Ser Glu Val Trp Gly Tyr Gly Phe Leu Ser
                 125                 130                 135

 Val Thr Ile Ile Asn Leu Ala Ser Leu Leu Gly Leu Ile Leu Thr
                 140                 145                 150

 Pro Leu Ile Lys Lys Ser Tyr Phe Pro Lys Ile Leu Thr Phe Phe
                 155                 160                 165

 Val Gly Leu Ala Ile Gly Thr Leu Phe Ser Asn Ala Ile Phe Gln
                 170                 175                 180

 Leu Ile Pro Glu Ala Phe Gly Phe Asp Pro Lys Val Asp Ser Tyr
                 185                 190                 195

 Val Glu Lys Ala Val Ala Val Phe Gly Gly Phe Tyr Leu Leu Phe
                 200                 205                 210

 Phe Phe Glu Arg Met Leu Lys Met Leu Leu Lys Thr Tyr Gly Gln
                 215                 220                 225

 Asn Gly His Thr His Phe Gly Asn Asp Asn Phe Gly Pro Gln Glu
                 230                 235                 240

 Lys Thr His Gln Pro Lys Ala Leu Pro Ala Ile Asn Gly Val Thr
                 245                 250                 255

 Cys Tyr Ala Asn Pro Ala Val Thr Glu Ala Asn Gly His Ile His
                 260                 265                 270

 Phe Asp Asn Val Ser Val Val Ser Leu Gln Asp Gly Lys Lys Glu
                 275                 280                 285

 Pro Ser Ser Cys Thr Cys Leu Lys Gly Pro Lys Leu Ser Glu Ile
                 290                 295                 300

 Gly Thr Ile Ala Trp Met Ile Thr Leu Cys Asp Ala Leu His Asn
                 305                 310                 315

 Phe Ile Asp Gly Leu Ala Ile Gly Ala Ser Cys Thr Leu Ser Leu
                 320                 325                 330

 Leu Gln Gly Leu Ser Thr Ser Ile Ala Ile Leu Cys Glu Glu Phe
                 335                 340                 345

 Pro His Glu Leu Gly Asp Phe Val Ile Leu Leu Asn Ala Gly Met
                 350                 355                 360

 Ser Thr Arg Gln Ala Leu Leu Phe Asn Phe Leu Ser Ala Cys Ser
                 365                 370                 375

 Cys Tyr Val Gly Leu Ala Phe Gly Ile Leu Val Gly Asn Asn Phe
                 380                 385                 390

 Ala Pro Asn Ile Ile Phe Ala Leu Ala Gly Gly Met Phe Leu Tyr
                 395                 400                 405

 Ile Ser Leu Ala Asp Met Phe Pro Glu Met Asn Asp Met Leu Arg
                 410                 415                 420

 Glu Lys Val Thr Gly Arg Lys Thr Asp Phe Thr Phe Phe Met Ile
                 425                 430                 435

 Gln Asn Ala Gly Met Leu Thr Gly Phe Thr Ala Ile Leu Leu Ile
                 440                 445                 450

 Thr Leu Tyr Ala Gly Glu Ile Glu Leu Glu
                 455                 460

<210> 6094
<211> 3874
<212> DNA
<213> Homo sapien

<400> 6094
 atggctcacc taaagcgact agtaaaatta cacattaaaa gacattacca 50

 taaaaagttc tggaagcttg gtgcagtaat ttttttcttt ataatagttt 100

 tggttttaat gcaaagagaa gtaagtgttc aatattccaa agaggaatca 150

 aggatggaaa ggaacatgaa aaacaaaaac aagatgttgg atttaatgct 200

 agaagctgta aacaatatta aggatgccat gccaaaaatg caaataggag 250

 cacctgtcag gcaaaacatt gatgctggtg agagaccttg tttgcaagga 300

 tattatacag cagcagaatt gaagcctgtc cttgaccgtc cacctcagga 350

 ttcaaatgca cctggtgctt ctggtaaagc attcaagaca accaatttaa 400

 gtgttgaaga gcaaaaggaa aaggaacgtg gggaagctaa acactgcttt 450

 aatgctttcg caagtgacag gatttctttg caccgagatc ttggaccaga 500

 cactcgacct cctgaatgta ttgaacaaaa atttaagcgc tgccctcccc 550

 tgcccaccac cagtgtcata atagtttttc ataatgaagc gtggtccacg 600

 ttgcttagaa ctgtccacag tgtgctctat tcttcacctg caatactgct 650

 gaaggaaatc attttggtgg atgatgctag tgtagatgag tacttacatg 700

 ataaactaga tgaatatgta aaacaatttt ctatagtaaa aatagtcaga 750

 caaagagaaa gaaaaggtct gatcactgct cggttgctag gagcaacagt 800

 cgcaacagct gaaacgctca catttttaga tgctcactgt gagtgtttct 850

 atggttggct agaacctctg ttggccagaa tagctgagaa ctacacggct 900

 gtcgtaagtc cagatattgc atccatagat ctgaacacgt ttgaattcaa 950

 caaaccttct ccttatggaa gtaaccataa ccgtggaaat tttgactgga 1000

 gtctttcatt tggctgggag tcgcttcctg atcatgagaa gcaaagaagg 1050

 aaagatgaaa cctacccaat taaaacaccc acttttgcag gaggactttt 1100

 ttccatatca aaagaatatt ttgagtatat tggaagctat gatgaagaaa 1150

 tggaaatctg gggaggtgaa aatatagaaa tgtctttcag agtatggcaa 1200

 tgtggtgggc agttggagat tatgccttgc tctgttgttg gacatgtttt 1250

 tcgcagcaaa agccctcata gctttccaaa aggcactcag gtgattgcta 1300

 gaaaccaagt tcgccttgca gaagtctgga tggatgaata caaggaaata 1350

 ttttatagga gaaatacaga tgcagcaaaa attgttaaac aaaaagcatt 1400

 tggtgatctt tcaaaaagat ttgaaataaa acaccgtctt cggtgtaaaa 1450

 attttacatg gtatctgaac aacatttatc cagaggtgta tgtgccagac 1500

 cttaatcctg ttatatctgg atacattaaa agcgttggtc agcctctatg 1550

 tctggatgtt ggagaaaaca atcaaggagg caaaccatta attatgtata 1600

 catgtcatgg acttggggga aaccagtact ttgaatactc tgctcaacat 1650

 gaaattcggc acaacatcca gaaggaatta tgtcttcatg ctgctcaagg 1700

 tctcgttcag ctgaaggcat gtacctacaa aggtcacaag acagttgtca 1750

 ctggagagca gatatgggag atccagaagg atcaacttct atacaatcca 1800

 ttcttaaaaa tgtgcctttc agcaaatgga gagcatccaa gtttagtgtc 1850

 atgcaaccca tcagatccac tccaaaaatg gatacttagc caaaatgatt 1900

 aagtgttcct taaaattaag ttgaaaaagg aaatattctt tctcataaaa 1950

 ctgtgactag gcatacactg tagtttttga aaattatgca aaagcagcta 2000

 aatgtaactt attccaagtg catttttctt atttatatct ttatgtagca 2050

 ctactacaga aattctgcaa gtttctgttt caaagcacaa taactagtaa 2100

 taccaaagac tatttcaaaa tgtccagatg taggggaaga gatgtttaca 2150

 gtatgatgaa aataattttc caagtaaagt gatgtttgtg tgttttgtac 2200

 acttagggat atatatatat agctacattc acacactcac aatttaaaat 2250

 atttccccta gttttttggg gggataggaa gaaagatttg ttactgtatt 2300

 tttttaacta cataaaaata gatcaataaa tgtcagcatt ggcctctgtg 2350

 tacaaaccaa gagcttttac agatccagaa tttattagtt taaaatgcag 2400

 gtgaactttt ttttgcgttt ggtttacttg tctgtcaaat gtttccttaa 2450

 acatgaaact gaataaggag aagagtattt ttaacactta aatttcttgg 2500

 caaattttaa aacatttttt agtctgtaat acactccact tgaagcactt 2550

 aagtcttcct taaatgactt ttcttaagta atgatactgt gtgttttccc 2600

 aaagcacttt taaaaaaatt tttataaatt actatctgtt gaaaaggtgt 2650

 ccttttcctt tcttctagta ttttttttct taccaaaatt cactaatctt 2700

 gaatgtttgt gatattaaat ttcaaatgca gaatacttga ctcatttaaa 2750

 gctaaatttt gttactgatt caattataat tgtaatggat ttttgacttt 2800

 gtaatggatt cttttcatca aaaagcctta ttatttttta tctatgtgga 2850

 aaacacaata aaaaatcctc aacactattg taatcatttg gttaagtgct 2900

 tattcctctt ttgggtaaaa tctgtaattg ataataggtg ggggaaaatg 2950

 aattttgtat gctgaatttc taagcgccta ttgtttgtaa aaccatcaga 3000

 tatttcttat ggcacaaaaa atgaggaata gcaaaattcc tgtgttcaat 3050

 atttagaaaa ttttgtatta atttctgata aagttcctta agcatctgat 3100

 agaatgatgt tttaaaaaaa tttgacgctt gcttaggaga tttaccactt 3150

 tttttttttg tttttcgtca ttttatattt agatctcctg tattcttgtt 3200

 cccgaagtaa aatacgatcg gtttcatatt ttaaatctgg cagagcctca 3250

 gctgtacgaa aaagagcata tactggttat tgaccctatc ttctcattgt 3300

 ttgtttgtaa gtttgaattt gtattaaaaa gcctgcattc tgagctggac 3350

 atggtggctc agcttctaat cccagcactt tggtaggcaa aggtgggagg 3400

 atcatttgag ctcaggagtt ccagaccagc ctgggcaaca tagcaaaatc 3450

 tcatctctac aaaaagtaaa aattaaaaaa tgaaattaaa aataaaatta 3500

 cctaggtgtg gtggcacgca tctgtagttc cagctataca ggaaggtgag 3550

 gcagaagcat tgcttgagct tgggagatcg aggctacagt gagctatgat 3600

 tacaccactg cacttcagtc tgtgtgactg agcaagactc tttcaaaaaa 3650

 aaaaaaaagc ctacattctc cagttgatta tttccaacta atgtgtatta 3700

 tgtgcctaat tttctatcag aagttgtatt aagcccgttt tcacactgct 3750

 gttaaagaca tacctgagac tgggtaattt ataaagaaaa ataggttcaa 3800

 tggacccaca ggtccgcgtg gctggggaag cttcacaatc atggcggaag 3850

 gtgaaagcat gtcttacgtg gaag 3874

<210> 6095
<211> 633
<212> PRT
<213> Homo sapien

<400> 6095
 Met Ala His Leu Lys Arg Leu Val Lys Leu His Ile Lys Arg His
   1               5                  10                  15

 Tyr His Lys Lys Phe Trp Lys Leu Gly Ala Val Ile Phe Phe Phe
                  20                  25                  30

 Ile Ile Val Leu Val Leu Met Gln Arg Glu Val Ser Val Gln Tyr
                  35                  40                  45

 Ser Lys Glu Glu Ser Arg Met Glu Arg Asn Met Lys Asn Lys Asn
                  50                  55                  60

 Lys Met Leu Asp Leu Met Leu Glu Ala Val Asn Asn Ile Lys Asp
                  65                  70                  75

 Ala Met Pro Lys Met Gln Ile Gly Ala Pro Val Arg Gln Asn Ile
                  80                  85                  90

 Asp Ala Gly Glu Arg Pro Cys Leu Gln Gly Tyr Tyr Thr Ala Ala
                  95                 100                 105

 Glu Leu Lys Pro Val Leu Asp Arg Pro Pro Gln Asp Ser Asn Ala
                 110                 115                 120

 Pro Gly Ala Ser Gly Lys Ala Phe Lys Thr Thr Asn Leu Ser Val
                 125                 130                 135

 Glu Glu Gln Lys Glu Lys Glu Arg Gly Glu Ala Lys His Cys Phe
                 140                 145                 150

 Asn Ala Phe Ala Ser Asp Arg Ile Ser Leu His Arg Asp Leu Gly
                 155                 160                 165

 Pro Asp Thr Arg Pro Pro Glu Cys Ile Glu Gln Lys Phe Lys Arg
                 170                 175                 180

 Cys Pro Pro Leu Pro Thr Thr Ser Val Ile Ile Val Phe His Asn
                 185                 190                 195

 Glu Ala Trp Ser Thr Leu Leu Arg Thr Val His Ser Val Leu Tyr
                 200                 205                 210

 Ser Ser Pro Ala Ile Leu Leu Lys Glu Ile Ile Leu Val Asp Asp
                 215                 220                 225

 Ala Ser Val Asp Glu Tyr Leu His Asp Lys Leu Asp Glu Tyr Val
                 230                 235                 240

 Lys Gln Phe Ser Ile Val Lys Ile Val Arg Gln Arg Glu Arg Lys
                 245                 250                 255

 Gly Leu Ile Thr Ala Arg Leu Leu Gly Ala Thr Val Ala Thr Ala
                 260                 265                 270

 Glu Thr Leu Thr Phe Leu Asp Ala His Cys Glu Cys Phe Tyr Gly
                 275                 280                 285

 Trp Leu Glu Pro Leu Leu Ala Arg Ile Ala Glu Asn Tyr Thr Ala
                 290                 295                 300

 Val Val Ser Pro Asp Ile Ala Ser Ile Asp Leu Asn Thr Phe Glu
                 305                 310                 315

 Phe Asn Lys Pro Ser Pro Tyr Gly Ser Asn His Asn Arg Gly Asn
                 320                 325                 330

 Phe Asp Trp Ser Leu Ser Phe Gly Trp Glu Ser Leu Pro Asp His
                 335                 340                 345

 Glu Lys Gln Arg Arg Lys Asp Glu Thr Tyr Pro Ile Lys Thr Pro
                 350                 355                 360

 Thr Phe Ala Gly Gly Leu Phe Ser Ile Ser Lys Glu Tyr Phe Glu
                 365                 370                 375

 Tyr Ile Gly Ser Tyr Asp Glu Glu Met Glu Ile Trp Gly Gly Glu
                 380                 385                 390

 Asn Ile Glu Met Ser Phe Arg Val Trp Gln Cys Gly Gly Gln Leu
                 395                 400                 405

 Glu Ile Met Pro Cys Ser Val Val Gly His Val Phe Arg Ser Lys
                 410                 415                 420

 Ser Pro His Ser Phe Pro Lys Gly Thr Gln Val Ile Ala Arg Asn
                 425                 430                 435

 Gln Val Arg Leu Ala Glu Val Trp Met Asp Glu Tyr Lys Glu Ile
                 440                 445                 450

 Phe Tyr Arg Arg Asn Thr Asp Ala Ala Lys Ile Val Lys Gln Lys
                 455                 460                 465

 Ala Phe Gly Asp Leu Ser Lys Arg Phe Glu Ile Lys His Arg Leu
                 470                 475                 480

 Arg Cys Lys Asn Phe Thr Trp Tyr Leu Asn Asn Ile Tyr Pro Glu
                 485                 490                 495

 Val Tyr Val Pro Asp Leu Asn Pro Val Ile Ser Gly Tyr Ile Lys
                 500                 505                 510

 Ser Val Gly Gln Pro Leu Cys Leu Asp Val Gly Glu Asn Asn Gln
                 515                 520                 525

 Gly Gly Lys Pro Leu Ile Met Tyr Thr Cys His Gly Leu Gly Gly
                 530                 535                 540

 Asn Gln Tyr Phe Glu Tyr Ser Ala Gln His Glu Ile Arg His Asn
                 545                 550                 555

 Ile Gln Lys Glu Leu Cys Leu His Ala Ala Gln Gly Leu Val Gln
                 560                 565                 570

 Leu Lys Ala Cys Thr Tyr Lys Gly His Lys Thr Val Val Thr Gly
                 575                 580                 585

 Glu Gln Ile Trp Glu Ile Gln Lys Asp Gln Leu Leu Tyr Asn Pro
                 590                 595                 600

 Phe Leu Lys Met Cys Leu Ser Ala Asn Gly Glu His Pro Ser Leu
                 605                 610                 615

 Val Ser Cys Asn Pro Ser Asp Pro Leu Gln Lys Trp Ile Leu Ser
                 620                 625                 630

 Gln Asn Asp


<210> 6096
<211> 1505
<212> DNA
<213> Homo sapien

<400> 6096
 ccacgtggtg gctttctcac gctagccctc tttggtcctc cttgacgtcc 50

 cgggcctgtg ggcccgcttt ctgccgagat gccgaaggtc aagtcggggg 100

 ccatcggccg ccgccgcggg cggcaggagc agcgccggga gctgaagagc 150

 gctggaggac tcatgttcaa cacggggatt gggcagcaca ttttgaaaaa 200

 tcctctcatt attaacagca ttatcgataa ggctgcctta agaccaactg 250

 atgtagtgct ggaagttgga cctggaactg gcaacatgac tgtaaagttg 300

 ttagaaaagg caaaaaaggt tgttgcttgt gaacttgacc caaggctagt 350

 agctgaactt cacaaaagag ttcagggcac gcctgtggcc agcaaacttc 400

 aagtactggt gggtgatgtg ctgaaaacag atttgccatt ctttgatact 450

 tgtgtggcaa atttgcctta tcagatctct tcgccttttg tcttcaagct 500

 gttgctacat cgaccttttt tcaggtgtgc tatacttatg tttcaaagag 550

 aatttgccct ccgactggtt gcaaaacctg gagataagtt atactgcaga 600

 ctctcaatta atacacagct gttggcacgt gtggaccatc taatgaaagt 650

 gggaaagaat aacttcagac caccgcccaa ggtggaatcc agtgttgtaa 700

 ggatagaacc taagaatcca ccaccaccca tcaattttca ggaatgggat 750

 ggtctagtaa ggataacctt tgttaggaaa aacaagacac tctctgctgc 800

 atttaaatca agtgcagtgc aacaactctt ggaaaaaaac tacagaattc 850

 actgttcagt ccataatatt ataataccag aagatttcag catagcagat 900

 aaaatacagc aaatcctaac cagcacaggt tttagtgaca aacgggcccg 950

 ttccatggac atagatgact tcatcagatt gctacatgga ttcaacgcag 1000

 aaggtattca tttttcctag gtatttggaa aacagaaatt ttcaaggtca 1050

 agaaaagaaa tgaattttgt attttttgta tttgagaaga taatgctttt 1100

 gctttactga gacattattt acttgactat ttttggttca atactactac 1150

 tgttgtcacc atttatgatt ctgaatttta aagttggaaa gttctaagta 1200

 tcaaagtttt taatatataa tgctggtcca atctattcat aataatcttc 1250

 aagttcagga gccgcagaga cgcacaactt tacacttatc atttctaaca 1300

 gtttattgta taaagatgtt actcttctat ttactgttat atactgtaag 1350

 gccttcttta ggcctttagc tctgttcctc cagtaataaa aaagttaaaa 1400

 tatgcttcac tagtcacaca ttccccatac catttcgtgt tattcacatt 1450

 ccccgtacca tttcttgtta ttcacatgta cagtaaaaca attgtttctt 1500

 aaatt 1505

<210> 6097
<211> 313
<212> PRT
<213> Homo sapien

<400> 6097
 Met Pro Lys Val Lys Ser Gly Ala Ile Gly Arg Arg Arg Gly Arg
   1               5                  10                  15

 Gln Glu Gln Arg Arg Glu Leu Lys Ser Ala Gly Gly Leu Met Phe
                  20                  25                  30

 Asn Thr Gly Ile Gly Gln His Ile Leu Lys Asn Pro Leu Ile Ile
                  35                  40                  45

 Asn Ser Ile Ile Asp Lys Ala Ala Leu Arg Pro Thr Asp Val Val
                  50                  55                  60

 Leu Glu Val Gly Pro Gly Thr Gly Asn Met Thr Val Lys Leu Leu
                  65                  70                  75

 Glu Lys Ala Lys Lys Val Val Ala Cys Glu Leu Asp Pro Arg Leu
                  80                  85                  90

 Val Ala Glu Leu His Lys Arg Val Gln Gly Thr Pro Val Ala Ser
                  95                 100                 105

 Lys Leu Gln Val Leu Val Gly Asp Val Leu Lys Thr Asp Leu Pro
                 110                 115                 120

 Phe Phe Asp Thr Cys Val Ala Asn Leu Pro Tyr Gln Ile Ser Ser
                 125                 130                 135

 Pro Phe Val Phe Lys Leu Leu Leu His Arg Pro Phe Phe Arg Cys
                 140                 145                 150

 Ala Ile Leu Met Phe Gln Arg Glu Phe Ala Leu Arg Leu Val Ala
                 155                 160                 165

 Lys Pro Gly Asp Lys Leu Tyr Cys Arg Leu Ser Ile Asn Thr Gln
                 170                 175                 180

 Leu Leu Ala Arg Val Asp His Leu Met Lys Val Gly Lys Asn Asn
                 185                 190                 195

 Phe Arg Pro Pro Pro Lys Val Glu Ser Ser Val Val Arg Ile Glu
                 200                 205                 210

 Pro Lys Asn Pro Pro Pro Pro Ile Asn Phe Gln Glu Trp Asp Gly
                 215                 220                 225

 Leu Val Arg Ile Thr Phe Val Arg Lys Asn Lys Thr Leu Ser Ala
                 230                 235                 240

 Ala Phe Lys Ser Ser Ala Val Gln Gln Leu Leu Glu Lys Asn Tyr
                 245                 250                 255

 Arg Ile His Cys Ser Val His Asn Ile Ile Ile Pro Glu Asp Phe
                 260                 265                 270

 Ser Ile Ala Asp Lys Ile Gln Gln Ile Leu Thr Ser Thr Gly Phe
                 275                 280                 285

 Ser Asp Lys Arg Ala Arg Ser Met Asp Ile Asp Asp Phe Ile Arg
                 290                 295                 300

 Leu Leu His Gly Phe Asn Ala Glu Gly Ile His Phe Ser
                 305                 310

<210> 6098
<211> 1654
<212> DNA
<213> Homo sapien

<400> 6098
 atcaaacact gttatgcaca taatgcagca ctgtgatcta atttaaataa 50

 tactttttta ttatttatac tactatatat aatatacatc aacacttttg 100

 ctatataacc taagtgataa ccctctttta gttacctgcc aaactctgga 150

 cttggtttat attgcagtta acacagttac aaagctgtaa tggtgtcttt 200

 ttttcctttg taacggaatg tgtaaatcaa agtatataca ttgtgtggtg 250

 ttcctgtttc tggagtttca tgaggattta cacatggcat tcagtgttct 300

 gtatagatct gcctaccttt gtgaattcat ctgttaaccc ctcttccttt 350

 gagagagcac cggcgatggt ggttaactcc ttgtgttttc tctctctcct 400

 actggttatt cttgaattaa gcacagactc gtcagctcgg ttgctttatc 450

 atgaataatg tgtgtgacct tgcagttctt ccacagttca gcaaacaagt 500

 gctagcttca ctgaccaaaa attaaggaag gaaaacacag tttttaaaac 550

 gatccatctt ttaacagccg aaaccgatgt gtctatggtg ctgcaccttg 600

 ctgttgtact tctgaaatca gacgtgtgtg aacgatcatt tctgacttaa 650

 ccgtgagatg ctcacgagta cccttcctgt tgttttgtta gcattgaaat 700

 cgagactatt tatttggaat atatacaaca gtgtttttcc actgtatttc 750

 atttgcaaaa gttgagaact gctttctcta ccttttgcaa aataattgat 800

 attccatatt ggattctcaa agacttcgat atggtgaacc tattaaacct 850

 agaaattgta ttcatccttt catgactgtg gcctgagttc cccagcccct 900

 ctcctccttt tttttagatg agatttagca cactctcagt tatttaaaca 950

 tgcaacattt cttgagtatg tatgttgagg ccatctgagc tcatagctga 1000

 ttcagtaacc agtttcatgc tgtgtcattc acactcacta cttaatactg 1050

 ccatggtgaa aatgtggagg aaaaatgtat ccatgtgtgt ctgggaagca 1100

 tatacacttg tacatttttt aatactctga ttctgtaaca tttctgagtt 1150

 ttgttttgtt ttacagaaaa aaaaaaaaaa gtgataaagc aatcagaaga 1200

 ccaagaggtt tactattgat gcttagggtc gtctgacctt ggctggccaa 1250

 tagacctaca cggccaaatt aatttacgag agtaataatt tttcaaaagc 1300

 caattttttt tctgtatttt ctgtatgaaa ctgccaatat catgaataga 1350

 aagggagaac cataaaggag aaagaacgtg atgttctgtt atgttcatgt 1400

 aaacctaaag aaacagtgtg gaggcaggcg cgatcagccg aactctaggg 1450

 acttggtgtt gcttggaagg catccatacc tgcattttgc attcttcgta 1500

 tgtaatcata ttgccaaaga caaactattt catcatttat tgtaaataac 1550

 acttttcccc agacctacca taaagtttct gtgatgtatt gtcttccagt 1600

 tgcaataaaa attactgagt tgcatcaaaa aaaaaaaaaa aaaaaaaaaa 1650

 aaaa 1654

<210> 6099
<211> 62
<212> PRT
<213> Homo sapien

<400> 6099
 Met Arg Ile Tyr Thr Trp His Ser Val Phe Cys Ile Asp Leu Pro
   1               5                  10                  15

 Thr Phe Val Asn Ser Ser Val Asn Pro Ser Ser Phe Glu Arg Ala
                  20                  25                  30

 Pro Ala Met Val Val Asn Ser Leu Cys Phe Leu Ser Leu Leu Leu
                  35                  40                  45

 Val Ile Leu Glu Leu Ser Thr Asp Ser Ser Ala Arg Leu Leu Tyr
                  50                  55                  60

 His Glu


<210> 6100
<211> 1537
<212> DNA
<213> Homo sapien

<400> 6100
 gaggaagaag aatctgtata tctgtatata ttggctagca aatgtgccct 50

 gctctctccc ctcttaaaaa tagcagcaac ccatctttgc aaagaagctt 100

 gcctatagag caggcactct gtgaatggac tgtgctttta cgaccctaca 150

 gggtatcaag atactgtgca gctcgccaac aaggattaat tgcaaggact 200

 ggtagatcga atttactgaa gacttggagc ttgcttctga gaacaaacgc 250

 aaaaggacag taaactgtgg accttgaagt tagcagcgtg ggcttcctct 300

 aatattacac cgtaaaaggc attgatcacc ataagaagga acatttgtga 350

 aggtactcca gtgccagaaa gaggcacaaa gcagacattc gtagagaaac 400

 atggatgaaa caggaaatct gacagtatct tctgccacat gccatgacac 450

 tattgatgac ttccgcaatc aagtgtattc caccttgtac tctatgatct 500

 ctgttgtagg cttctttggc aatggctttg tgctctatgt cctcataaaa 550

 acctatcaca agaagtcagc cttccaagta tacatgatta atttagcagt 600

 agcagatcta ctttgtgtgt gcacactgcc tctccgtgtg gtctattatg 650

 ttcacaaagg catttggctc tttggtgact tcttgtgccg cctcagcacc 700

 tatgctttgt atgtcaacct ctattgtagc atcttcttta tgacagccat 750

 gagctttttc cggtgcattg caattgtttt tccagtccag aacattaatt 800

 tggttacaca gaaaaaagcc aggtttgtgt gtgtaggtat ttggattttt 850

 gtgattttga ccagttctcc atttctaatg gccaaaccac aaaaagatga 900

 gaaaaataat accaagtgct ttgagccccc acaagacaat caaactaaaa 950

 atcatgtttt ggtcttgcat tatgtgtcat tgtttgttgg ctttatcatc 1000

 ccttttgtta ttataattgt ctgttacaca atgatcattt tgaccttact 1050

 aaaaaaatca atgaaaaaaa atctgtcaag tcataaaaag gctataggaa 1100

 tgatcatggt cgtgaccgct gcctttttag tcagtttcat gccatatcat 1150

 attcaacgta ccattcacct tcatttttta cacaatgaaa ctaaaccctg 1200

 tgattctgtc cttagaatgc agaagtccgt ggtcataacc ttgtctctgg 1250

 ctgcatccaa ttgttgcttt gaccctctcc tatatttctt ttctgggggt 1300

 aactttagga aaaggctgtc tacattcaga aagcattctt tgtccagcgt 1350

 gacttatgta cccagaaaga aggcctcttt gccagaaaaa ggagaagaaa 1400

 tatgtaaagt atagtttaaa cccatttcca gtccaaacca atgaaaatag 1450

 tttcccaaat aagtattttg tcaaatcatt tacaaaaaaa ataaaaattt 1500

 tacttaatat tttaaaaaaa aaaaaaaaaa aaaaaaa 1537

<210> 6101
<211> 337
<212> PRT
<213> Homo sapien

<400> 6101
 Met Asp Glu Thr Gly Asn Leu Thr Val Ser Ser Ala Thr Cys His
   1               5                  10                  15

 Asp Thr Ile Asp Asp Phe Arg Asn Gln Val Tyr Ser Thr Leu Tyr
                  20                  25                  30

 Ser Met Ile Ser Val Val Gly Phe Phe Gly Asn Gly Phe Val Leu
                  35                  40                  45

 Tyr Val Leu Ile Lys Thr Tyr His Lys Lys Ser Ala Phe Gln Val
                  50                  55                  60

 Tyr Met Ile Asn Leu Ala Val Ala Asp Leu Leu Cys Val Cys Thr
                  65                  70                  75

 Leu Pro Leu Arg Val Val Tyr Tyr Val His Lys Gly Ile Trp Leu
                  80                  85                  90

 Phe Gly Asp Phe Leu Cys Arg Leu Ser Thr Tyr Ala Leu Tyr Val
                  95                 100                 105

 Asn Leu Tyr Cys Ser Ile Phe Phe Met Thr Ala Met Ser Phe Phe
                 110                 115                 120

 Arg Cys Ile Ala Ile Val Phe Pro Val Gln Asn Ile Asn Leu Val
                 125                 130                 135

 Thr Gln Lys Lys Ala Arg Phe Val Cys Val Gly Ile Trp Ile Phe
                 140                 145                 150

 Val Ile Leu Thr Ser Ser Pro Phe Leu Met Ala Lys Pro Gln Lys
                 155                 160                 165

 Asp Glu Lys Asn Asn Thr Lys Cys Phe Glu Pro Pro Gln Asp Asn
                 170                 175                 180

 Gln Thr Lys Asn His Val Leu Val Leu His Tyr Val Ser Leu Phe
                 185                 190                 195

 Val Gly Phe Ile Ile Pro Phe Val Ile Ile Ile Val Cys Tyr Thr
                 200                 205                 210

 Met Ile Ile Leu Thr Leu Leu Lys Lys Ser Met Lys Lys Asn Leu
                 215                 220                 225

 Ser Ser His Lys Lys Ala Ile Gly Met Ile Met Val Val Thr Ala
                 230                 235                 240

 Ala Phe Leu Val Ser Phe Met Pro Tyr His Ile Gln Arg Thr Ile
                 245                 250                 255

 His Leu His Phe Leu His Asn Glu Thr Lys Pro Cys Asp Ser Val
                 260                 265                 270

 Leu Arg Met Gln Lys Ser Val Val Ile Thr Leu Ser Leu Ala Ala
                 275                 280                 285

 Ser Asn Cys Cys Phe Asp Pro Leu Leu Tyr Phe Phe Ser Gly Gly
                 290                 295                 300

 Asn Phe Arg Lys Arg Leu Ser Thr Phe Arg Lys His Ser Leu Ser
                 305                 310                 315

 Ser Val Thr Tyr Val Pro Arg Lys Lys Ala Ser Leu Pro Glu Lys
                 320                 325                 330

 Gly Glu Glu Ile Cys Lys Val
                 335

<210> 6102
<211> 2147
<212> DNA
<213> Homo sapien

<400> 6102
 ggctctttta aatgacccca ggcgtcgtgt attgaatcct agactcacgt 50

 ccgtctcgcc ggcgcccgag ccagtccgcg cgcaccgcgt ctgcgtcccc 100

 gaaagccccg cccgcaaggg ctgccctgcc tacctggtct ccgacgtgct 150

 cgtctggagg gcggtgcgag gggccgagcc gacgagatgt tcttgctgcc 200

 tcttccggct gcggggcgag tagtcgtccg acgtctggcc gtagtacgtt 250

 ctgggagccg gagtctctcc accgcagaca tgacgaaggg ccttgtttta 300

 ggaatctatt ccaaagaaaa agaagatgat gtgccacagt tcacaagtgc 350

 aggagagaat tttgataaat tgttagctgg aaagctgaga gagactttga 400

 acatatctgg accacctctg aaggcaggga agactcgaac cttttatggt 450

 ctgcatcagg acttccccag cgtggtgcta gttggcctcg gcaaaaaggc 500

 agctggaatc gacgaacagg aaaactggca tgaaggcaaa gaaaacatca 550

 gagctgctgt tgcagcgggg tgcaggcaga ttcaagacct ggagctctcg 600

 tctgtggagg tggatccctg tggagacgct caggctgctg cggagggagc 650

 ggtgcttggt ctctatgaat acgatgacct aaagcaaaaa aagaagatgg 700

 ctgtgtcggc aaagctctat ggaagtgggg atcaggaggc ctggcagaaa 750

 ggagtcctgt ttgcttctgg gcagaacttg gcacgccaat tgatggagac 800

 gccagccaat gagatgacgc caaccagatt tgccgaaatt attgagaaga 850

 atctcaaaag tgctagtagt aaaaccgagg tccatatcag acccaagtct 900

 tggattgagg aacaggcaat gggatcattc ctcagtgtgg ccaaaggatc 950

 tgacgagccc ccagtcttct tggaaattca ctacaaaggc agccccaatg 1000

 caaacgaacc acccctggtg tttgttggga aaggaattac ctttgacagt 1050

 ggtggtatct ccatcaaggc ttctgcaaat atggacctca tgagggctga 1100

 catgggagga gctgcaacta tatgctcagc catcgtgtct gctgcaaagt 1150

 taaatttgcc cattaatatt ataggtctgg cccctctttg tgaaaatatg 1200

 cccagcggca aggccaacaa gccgggggat gttgttagag ccaaaaacgg 1250

 gaagaccatc caggttgata acactgatgc tgaggggagg ctcatactgg 1300

 ctgatgcgct ctgttacgca cacacgttta acccgaaggt catcctcaat 1350

 gccgccacct taacaggtgc catggatgta gctttgggat caggtgccac 1400

 tggggtcttt accaattcat cctggctctg gaacaaactc ttcgaggcca 1450

 gcattgaaac aggggaccgt gtctggagga tgcctctctt cgaacattat 1500

 acaagacagg ttgtagattg ccagcttgct gatgttaaca acattggaaa 1550

 atacagatct gcaggagcat gtacagctgc agcattcctg aaagaattcg 1600

 taactcatcc taagtgggca catttagaca tagcaggcgt gatgaccaac 1650

 aaagatgaag ttccctatct acggaaaggc atgactggga ggcccacaag 1700

 gactctcatt gagttcttac ttcgtttcag tcaagacaat gcttagttca 1750

 gatactcaaa aatgtcttca ctctgtctta aattggacag ttgaacttaa 1800

 aaggtttttg aataaatgga tgaaaatctt ttaacggaga caaaggatgg 1850

 tatttaaaaa tgtagaacac aatgaaattt gtatgccttg attttttttt 1900

 catttcacac aaagatttat aaaggtaaag ttaatatctt acttgataag 1950

 gatttttaag atactctata aatgattaaa atttttagaa cttcctaatc 2000

 acttttcaga gtatatgttt ttcattgaga agcaaaattg taactcagat 2050

 ttgtgatgct aggaacatga gcaaactgaa aattactatg cacttgtcag 2100

 aaacaataaa tgcaacttgt tgtgaaaaaa aaaaaaaaaa aaaaaaa 2147

<210> 6103
<211> 519
<212> PRT
<213> Homo sapien

<400> 6103
 Met Phe Leu Leu Pro Leu Pro Ala Ala Gly Arg Val Val Val Arg
   1               5                  10                  15

 Arg Leu Ala Val Val Arg Ser Gly Ser Arg Ser Leu Ser Thr Ala
                  20                  25                  30

 Asp Met Thr Lys Gly Leu Val Leu Gly Ile Tyr Ser Lys Glu Lys
                  35                  40                  45

 Glu Asp Asp Val Pro Gln Phe Thr Ser Ala Gly Glu Asn Phe Asp
                  50                  55                  60

 Lys Leu Leu Ala Gly Lys Leu Arg Glu Thr Leu Asn Ile Ser Gly
                  65                  70                  75

 Pro Pro Leu Lys Ala Gly Lys Thr Arg Thr Phe Tyr Gly Leu His
                  80                  85                  90

 Gln Asp Phe Pro Ser Val Val Leu Val Gly Leu Gly Lys Lys Ala
                  95                 100                 105

 Ala Gly Ile Asp Glu Gln Glu Asn Trp His Glu Gly Lys Glu Asn
                 110                 115                 120

 Ile Arg Ala Ala Val Ala Ala Gly Cys Arg Gln Ile Gln Asp Leu
                 125                 130                 135

 Glu Leu Ser Ser Val Glu Val Asp Pro Cys Gly Asp Ala Gln Ala
                 140                 145                 150

 Ala Ala Glu Gly Ala Val Leu Gly Leu Tyr Glu Tyr Asp Asp Leu
                 155                 160                 165

 Lys Gln Lys Lys Lys Met Ala Val Ser Ala Lys Leu Tyr Gly Ser
                 170                 175                 180

 Gly Asp Gln Glu Ala Trp Gln Lys Gly Val Leu Phe Ala Ser Gly
                 185                 190                 195

 Gln Asn Leu Ala Arg Gln Leu Met Glu Thr Pro Ala Asn Glu Met
                 200                 205                 210

 Thr Pro Thr Arg Phe Ala Glu Ile Ile Glu Lys Asn Leu Lys Ser
                 215                 220                 225

 Ala Ser Ser Lys Thr Glu Val His Ile Arg Pro Lys Ser Trp Ile
                 230                 235                 240

 Glu Glu Gln Ala Met Gly Ser Phe Leu Ser Val Ala Lys Gly Ser
                 245                 250                 255

 Asp Glu Pro Pro Val Phe Leu Glu Ile His Tyr Lys Gly Ser Pro
                 260                 265                 270

 Asn Ala Asn Glu Pro Pro Leu Val Phe Val Gly Lys Gly Ile Thr
                 275                 280                 285

 Phe Asp Ser Gly Gly Ile Ser Ile Lys Ala Ser Ala Asn Met Asp
                 290                 295                 300

 Leu Met Arg Ala Asp Met Gly Gly Ala Ala Thr Ile Cys Ser Ala
                 305                 310                 315

 Ile Val Ser Ala Ala Lys Leu Asn Leu Pro Ile Asn Ile Ile Gly
                 320                 325                 330

 Leu Ala Pro Leu Cys Glu Asn Met Pro Ser Gly Lys Ala Asn Lys
                 335                 340                 345

 Pro Gly Asp Val Val Arg Ala Lys Asn Gly Lys Thr Ile Gln Val
                 350                 355                 360

 Asp Asn Thr Asp Ala Glu Gly Arg Leu Ile Leu Ala Asp Ala Leu
                 365                 370                 375

 Cys Tyr Ala His Thr Phe Asn Pro Lys Val Ile Leu Asn Ala Ala
                 380                 385                 390

 Thr Leu Thr Gly Ala Met Asp Val Ala Leu Gly Ser Gly Ala Thr
                 395                 400                 405

 Gly Val Phe Thr Asn Ser Ser Trp Leu Trp Asn Lys Leu Phe Glu
                 410                 415                 420

 Ala Ser Ile Glu Thr Gly Asp Arg Val Trp Arg Met Pro Leu Phe
                 425                 430                 435

 Glu His Tyr Thr Arg Gln Val Val Asp Cys Gln Leu Ala Asp Val
                 440                 445                 450

 Asn Asn Ile Gly Lys Tyr Arg Ser Ala Gly Ala Cys Thr Ala Ala
                 455                 460                 465

 Ala Phe Leu Lys Glu Phe Val Thr His Pro Lys Trp Ala His Leu
                 470                 475                 480

 Asp Ile Ala Gly Val Met Thr Asn Lys Asp Glu Val Pro Tyr Leu
                 485                 490                 495

 Arg Lys Gly Met Thr Gly Arg Pro Thr Arg Thr Leu Ile Glu Phe
                 500                 505                 510

 Leu Leu Arg Phe Ser Gln Asp Asn Ala
                 515

<210> 6104
<211> 2912
<212> DNA
<213> Homo sapien

<400> 6104
 aaggcgcggg ccccggcgcg gcggggaggg ctcggccgga ggggaggctg 50

 cggcgcgcgg ccggtcgctg cgggcccggg ccccaagccg tgccgctccg 100

 ctcgcccggg cccagccgag gccgctgcgc ccccgcctcc tcgcgggagg 150

 actcgctcca aactccctga acttcgggga cagtcccccg aagcggcgaa 200

 actctcaggg ttggcaaccc tgcccaggga cccccatccc gggcggcgct 250

 ccggacgccc tcccctcacc gcgcccccgc agacacgtgc ctggactccg 300

 agggcttctg gagccaccgg ccgggccacg atgctcatga ggaaagtgcc 350

 cggcttcgtc ccggcctccc cgtgggggct gcggctgccg cagaagttcc 400

 tcttcctcct cttcctctcg ggcctggtca ccctgtgctt cggggccctc 450

 ttcctgctgc cccactcctc tcgcctcaag cgcctcttcc tggccccccg 500

 gacccagcag cctggtctgg aagtggtggc tgaaatcgcc ggccatgccc 550

 cggcccgcga gcaggagccg cctcccaacc cggcccccgc cgcgccggcc 600

 ccgggcgagg atgaccccag cagctgggcc agtccccgcc gcaggaaagg 650

 ggggctgcgg cgcacccgcc ccactggacc ccgcgaggag gccacggcgg 700

 cccggggcaa tagcatcccg gcctccaggc ccggggacga gggcgtccct 750

 ttccgctttg acttcaacgc attccggagc cgtctccgcc acccggtcct 800

 gggaacgagg gccgatgaga gtcaggagcc ccagagccaa gtgcgagccc 850

 agcgggagaa aatcaaggag atgatgcagt ttgcttggca gagctataag 900

 cgttatgcaa tggggaaaaa cgaactccgt ccactaacaa aagatggcta 950

 cgagggtaac atgttcggag gcctcagcgg ggcaacagtc attgactccc 1000

 tcgataccct ctacctcatg gagctgaagg aggagttcca ggaggccaag 1050

 gcctgggtgg gagagagctt ccacctgaac gtgagcggag aagcatcctt 1100

 gtttgaggtg aacatccgct acatcggggg actcctctca gccttctacc 1150

 tgacaggaga agaggtgttc cgaataaagg ccatcaggct gggagagaag 1200

 ctcctgccgg cgttcaacac ccccacggga atcccaaagg gcgtggtgag 1250

 cttcaaaagt gggaactggg gctgggccac agccggcagc agcagcatct 1300

 tggcggagtt tggatccctg cacttggaat tcttacacct cactgaactc 1350

 tctggcaacc aggtcttcgc tgaaaaggtc aggaacatcc gcaaggtcct 1400

 caggaagatc gaaaagccct ttggcctcta ccccaacttc ctcagcccag 1450

 tgagtgggaa ctgggtgcaa caccatgtct cagttggagg actcggggac 1500

 agtttttatg aatatttgat caaatcctgg ttgatgtcgg gcaagacaga 1550

 tatggaggct aaaaatatgt actacgaagc cttggaggcg atagagacct 1600

 acttgctgaa tgtctctccc ggggggctga cctacattgc cgagtggcga 1650

 ggggggattc tggaccacaa gatggggcac ctggcctgtt tctccggggg 1700

 catgatcgcc cttggcgccg aggatgccaa ggaagaaaag agggcccact 1750

 accgagagct cgcagcccag atcaccaaga cgtgtcacga gtcatacgcc 1800

 cgctcagaca ccaaacttgg gcctgaggcc ttctggttta actccggcag 1850

 agaggccgtg gccacccagc tgagcgagag ctactacatc ctccggccag 1900

 aggtggtgga gagctacatg tacctgtggc gacagaccca caaccccatc 1950

 tacagggagt ggggctggga ggtggtgctg gccttggaga aatactgtcg 2000

 gacagaagcc ggtttctctg ggatccaaga cgtgtacagt agcaccccca 2050

 accacgacaa caagcagcag agcttctttc tagcggagac actaaagtat 2100

 ctctatcttc tgttctctga agatgacttg ctctccctgg aagactgggt 2150

 gttcaacacc gaggcccacc cactcccggt gaaccactca gacagctccg 2200

 gcagagcctg gggcagacac tgaccccatc tcctgccgcc gccctggggc 2250

 cgccgcaggg atgccttgcc ttttcaggat ttgagactgt tctcaaaggg 2300

 attgggaacg aaggccccat ctcgggcaga cccccagcag atgtgtcgga 2350

 caagcaactt cttttcctct gtgaggagac aagacttgga gactcagcga 2400

 tgtcaggcca gggccatggc cacactggcc cacacattcc tttctacaga 2450

 gaatttctat gaagcccact cacttgccat tccagggcca aaggaccgga 2500

 ggtttgcata tccgcccctt gtatttgatt tgcttccttt tggtttcttg 2550

 gtttttgttt ttgcttgatt ttgtcttttc tctacagttt agttttgtca 2600

 caattacaca tatagttttc aaaatcatgc actttctaaa atggtgtcat 2650

 cctgaaaaac aaaacccagt gtttgcacac acacaaaatc ttgaccccgt 2700

 tatctatatt ttaaatgctt tttgcccaac actgacccta tgttcaactt 2750

 tgtgtcattt accttataat ttgaggaggg gtttcccttt gggcctcagt 2800

 gttacaaatt actagtgcta ttttcattat tattgtaatg gaaaaatctg 2850

 tggactagaa taaaagagtt tattgaataa gaaaaaaaaa aaaaaaaaaa 2900

 aaaaaaaaaa aa 2912

<210> 6105
<211> 630
<212> PRT
<213> Homo sapien

<400> 6105
 Met Leu Met Arg Lys Val Pro Gly Phe Val Pro Ala Ser Pro Trp
   1               5                  10                  15

 Gly Leu Arg Leu Pro Gln Lys Phe Leu Phe Leu Leu Phe Leu Ser
                  20                  25                  30

 Gly Leu Val Thr Leu Cys Phe Gly Ala Leu Phe Leu Leu Pro His
                  35                  40                  45

 Ser Ser Arg Leu Lys Arg Leu Phe Leu Ala Pro Arg Thr Gln Gln
                  50                  55                  60

 Pro Gly Leu Glu Val Val Ala Glu Ile Ala Gly His Ala Pro Ala
                  65                  70                  75

 Arg Glu Gln Glu Pro Pro Pro Asn Pro Ala Pro Ala Ala Pro Ala
                  80                  85                  90

 Pro Gly Glu Asp Asp Pro Ser Ser Trp Ala Ser Pro Arg Arg Arg
                  95                 100                 105

 Lys Gly Gly Leu Arg Arg Thr Arg Pro Thr Gly Pro Arg Glu Glu
                 110                 115                 120

 Ala Thr Ala Ala Arg Gly Asn Ser Ile Pro Ala Ser Arg Pro Gly
                 125                 130                 135

 Asp Glu Gly Val Pro Phe Arg Phe Asp Phe Asn Ala Phe Arg Ser
                 140                 145                 150

 Arg Leu Arg His Pro Val Leu Gly Thr Arg Ala Asp Glu Ser Gln
                 155                 160                 165

 Glu Pro Gln Ser Gln Val Arg Ala Gln Arg Glu Lys Ile Lys Glu
                 170                 175                 180

 Met Met Gln Phe Ala Trp Gln Ser Tyr Lys Arg Tyr Ala Met Gly
                 185                 190                 195

 Lys Asn Glu Leu Arg Pro Leu Thr Lys Asp Gly Tyr Glu Gly Asn
                 200                 205                 210

 Met Phe Gly Gly Leu Ser Gly Ala Thr Val Ile Asp Ser Leu Asp
                 215                 220                 225

 Thr Leu Tyr Leu Met Glu Leu Lys Glu Glu Phe Gln Glu Ala Lys
                 230                 235                 240

 Ala Trp Val Gly Glu Ser Phe His Leu Asn Val Ser Gly Glu Ala
                 245                 250                 255

 Ser Leu Phe Glu Val Asn Ile Arg Tyr Ile Gly Gly Leu Leu Ser
                 260                 265                 270

 Ala Phe Tyr Leu Thr Gly Glu Glu Val Phe Arg Ile Lys Ala Ile
                 275                 280                 285

 Arg Leu Gly Glu Lys Leu Leu Pro Ala Phe Asn Thr Pro Thr Gly
                 290                 295                 300

 Ile Pro Lys Gly Val Val Ser Phe Lys Ser Gly Asn Trp Gly Trp
                 305                 310                 315

 Ala Thr Ala Gly Ser Ser Ser Ile Leu Ala Glu Phe Gly Ser Leu
                 320                 325                 330

 His Leu Glu Phe Leu His Leu Thr Glu Leu Ser Gly Asn Gln Val
                 335                 340                 345

 Phe Ala Glu Lys Val Arg Asn Ile Arg Lys Val Leu Arg Lys Ile
                 350                 355                 360

 Glu Lys Pro Phe Gly Leu Tyr Pro Asn Phe Leu Ser Pro Val Ser
                 365                 370                 375

 Gly Asn Trp Val Gln His His Val Ser Val Gly Gly Leu Gly Asp
                 380                 385                 390

 Ser Phe Tyr Glu Tyr Leu Ile Lys Ser Trp Leu Met Ser Gly Lys
                 395                 400                 405

 Thr Asp Met Glu Ala Lys Asn Met Tyr Tyr Glu Ala Leu Glu Ala
                 410                 415                 420

 Ile Glu Thr Tyr Leu Leu Asn Val Ser Pro Gly Gly Leu Thr Tyr
                 425                 430                 435

 Ile Ala Glu Trp Arg Gly Gly Ile Leu Asp His Lys Met Gly His
                 440                 445                 450

 Leu Ala Cys Phe Ser Gly Gly Met Ile Ala Leu Gly Ala Glu Asp
                 455                 460                 465

 Ala Lys Glu Glu Lys Arg Ala His Tyr Arg Glu Leu Ala Ala Gln
                 470                 475                 480

 Ile Thr Lys Thr Cys His Glu Ser Tyr Ala Arg Ser Asp Thr Lys
                 485                 490                 495

 Leu Gly Pro Glu Ala Phe Trp Phe Asn Ser Gly Arg Glu Ala Val
                 500                 505                 510

 Ala Thr Gln Leu Ser Glu Ser Tyr Tyr Ile Leu Arg Pro Glu Val
                 515                 520                 525

 Val Glu Ser Tyr Met Tyr Leu Trp Arg Gln Thr His Asn Pro Ile
                 530                 535                 540

 Tyr Arg Glu Trp Gly Trp Glu Val Val Leu Ala Leu Glu Lys Tyr
                 545                 550                 555

 Cys Arg Thr Glu Ala Gly Phe Ser Gly Ile Gln Asp Val Tyr Ser
                 560                 565                 570

 Ser Thr Pro Asn His Asp Asn Lys Gln Gln Ser Phe Phe Leu Ala
                 575                 580                 585

 Glu Thr Leu Lys Tyr Leu Tyr Leu Leu Phe Ser Glu Asp Asp Leu
                 590                 595                 600

 Leu Ser Leu Glu Asp Trp Val Phe Asn Thr Glu Ala His Pro Leu
                 605                 610                 615

 Pro Val Asn His Ser Asp Ser Ser Gly Arg Ala Trp Gly Arg His
                 620                 625                 630

<210> 6106
<211> 6036
<212> DNA
<213> Homo sapien

<400> 6106
 agcgggctgg gtcctaggcc aggtctgggg taacctggaa cttccacctg 50

 ggctctgcgc taggtctctg tttcactccc tccccgcggg gcgcgcagct 100

 cgcgggtctt tggacaccac cggtcctgag tccgcggact gccattttca 150

 ttaagaactg ccacttagag gtaccaaaat aaagggtatt tgctaccttt 200

 aatacttgcc agttcaggtt ggaggcacag gcagcagcaa gaatggaaag 250

 aaatgttctt acaacatttt cacaggaaat gtcccagtta attttgaatg 300

 aaatgccaaa agctgaatat tccagtttat tcaatgattt tgttgaatct 350

 gaattttttt tgattgatgg ggattcatta cttatcacat gtatctgtga 400

 gatatcattt aagcctgggc agaacctcca tttcttctat ctggttgaac 450

 gctatcttgt ggatcttatt agcaaaggag gacaattcac catagttttc 500

 ttcaaggatg ccgagtatgc gtatttcaac ttccctgaac ttctttcttt 550

 gagaactgct ttaattcttc atcttcagaa gaataccacc attgatgttc 600

 gaacaacatt ttcgagatgc ttatcaaaag agtggggaag tttcttggaa 650

 gagagttacc catatttcct gatagttgca gacgaaggcc tgaacgatct 700

 acaaacacag cttttcaact ttttaatcat tcattcttgg gcaaggaagg 750

 tcaacgttgt actttcctca gggcaagaat ctgatgttct ttgcctttat 800

 gcataccttc ttccaagcat gtacagacac cagatttttt cctggaagaa 850

 taagcagaac attaaagatg cttatacaac cctgcttaac cagttggaaa 900

 gatttaagct ttcagcatta gcacctcttt ttggaagttt aaaatggaat 950

 aatattacgg aagaggcaca caagactgta tctctgctta cacaagtctg 1000

 gccagaagga tctgacattc ggcgtgtctt ttgtgttact tcatgctcat 1050

 tatctttgag aatgtaccat cgctttttag gaaacagaga gccctcctct 1100

 ggtcaggaaa ctgagatcca acaggtgaac agtaattgct taaccctgca 1150

 ggagatggaa gatttgtgta aactgcattg tctcactgtg gtttttctac 1200

 tccatctgcc tctttctcaa agagcttgtg ctagagtcat cacttcacat 1250

 tgggctgagg acatgaagcc tttattacaa atgaaaaagt ggtgtgaata 1300

 tttcatctta agaaatatac atacttttga attttggaat ctgaatttaa 1350

 ttcacctttc tgacttaaat gatgagcttt tgttgaagaa tattgctttt 1400

 tactatgaaa atgaaaatgt aaaaggccta catttgaatt tgggagatac 1450

 cattatgaaa gattatgaat atctctggaa taccgtatca aagttggtca 1500

 gagactttga ggttggacag ccatttcctc tgagaacaac aaaagtttgt 1550

 tttcttggaa agaaaccatc accaatcaaa gacagctcca atgaaatggt 1600

 gcccaatttg ggttttattc caacgtcatc ttttgtggtt gataaatttg 1650

 ctggagatat tttgaaagat ttgccttttc taaagagtga tgatcctatt 1700

 gttacttcac tggttaaaca aaaggaattt gatgaacttg tgcactggca 1750

 ttctcataaa cccctgagtg atgattatga caggtccagg tgtcagtttg 1800

 atgaaaaatc tagagaccct cgtgttctta gatctgtgca aaagtatcat 1850

 gttttccaac ggttttatgg gaattcatta gaaacagtct cttcgaaaat 1900

 catcgtgact caaactatta agtcaaagaa ggattttagt gggcccaaga 1950

 gcaaaaaggc acacgagacc aaggctgaaa taattgctag agagaataag 2000

 aaaaggttat ttgccaggga agaacaaaag gaagagcaaa agtggaatgc 2050

 tttgtcattt tctattgaag agcaattgaa agaaaattta cactctggaa 2100

 taaagagcct ggaagatttt ttgaaatcct gtaaaagtag ctgtgtgaaa 2150

 cttcaggttg aaatggtggg gttaactgct tgcttgaaag cctggaaaga 2200

 acattgccga agtgaagaag gtaaaaccac gaaagattta agtatagctg 2250

 ttcaggtgat gaaaaggatc cactccttga tggaaaaata ctcagaactt 2300

 ttacaagaag atgatcggca actcatagcc agatgcctta agtatttagg 2350

 atttgatgag ttggcaagtt ctttacatcc agcccaggat gcagaaaatg 2400

 atgtaaaagt gaagaaaagg aataaatatt caattggcat tgggccagct 2450

 cggttccaac tgcaatacat gggccattat ttgatacgag atgagagaaa 2500

 agacccagat cccagggtcc aggattttat tcccgacaca tggcagcgag 2550

 agctccttga tgttgtggat aagaatgagt cagcagtgat tgttgcccca 2600

 acgtcctcag gcaaaacata tgcctcctac tactgtatgg agaaagtgct 2650

 gaaggagagc gacgacgggg tggtcgtgta cgttgcaccc acaaaggccc 2700

 ttgttaatca agtggcagca actgttcaga atcgttttac gaaaaatctg 2750

 ccaagtggtg aagttctctg tggtgttttc accagggagt atcgtcatga 2800

 tgccttaaac tgtcaggtac ttattacagt gcctgcctgc tttgaaattc 2850

 tgctgcttgc tcctcatcgc caaaactggg tgaaaaagat cagatatgtt 2900

 atatttgatg aggttcattg tcttggtgga gaaattggag cagaaatctg 2950

 ggaacatctc cttgtcatga tccgatgtcc ctttttggct ctttcagcta 3000

 ccataagtaa tcctgaacat ctcaccgagt ggctacaatc ggtaaaatgg 3050

 tactggaaac aagaagacaa aataattgaa aataataccg cttctaaaag 3100

 acatgtgggt cgtcaggccg gctttcccaa agactacttg caagtaaaac 3150

 aatcgtataa agttagactt gtgctctatg gagagaggta taatgatcta 3200

 gagaagcatg tatgttcaat aaaacatggt gacattcatt ttgatcattt 3250

 tcacccatgt gctgcactaa caacagatca tattgaaagg tatggattcc 3300

 ctcctgatct taccctttca cctcgagaaa gcatccagct gtatgatgcc 3350

 atgtttcaaa tttggaaaag ttggcctcgg gcccaggaac tgtgcccaga 3400

 aaacttcatt cattttaaca ataaattagt cattaaaaag atggatgcta 3450

 ggaaatatga agagagtcta aaggcagaat taacaagttg gattaaaaat 3500

 ggcaacgtag agcaggccag aatggtactt cagaatctta gtcctgaagc 3550

 agatttgagt ccagaaaaca tgatcaccat gtttccactt ctagttgaaa 3600

 aactaaggaa aatggagaag ttacctgcac tatttttttt attcaagtta 3650

 ggagctgtag aaaacgcagc tgaaagtgtg agcactttcc taaagaaaaa 3700

 gcaggagaca aaaaggcctc ccaaagctga taaagaagcc catgtcatgg 3750

 ctaacaaact tcgaaaagtt aaaaaatcca tagagaaaca aaagatcata 3800

 gatgaaaaga gccagaaaaa aaccagaaat gtggatcaaa gcctaataca 3850

 tgaagctgaa catgataatc tagtgaagtg tctagagaag aacctggaaa 3900

 tcccacagga ctgcacatat gctgatcaaa aagcagtgga cactgagact 3950

 ttgcagaagg tatttggtcg agtaaaattt gaaagaaaag gtgaagaatt 4000

 gaaagccttg gcagaaaggg gtattggata tcatcacagt gctatgagtt 4050

 tcaaagaaaa acaattagtt gaaatcctct ttagaaaagg atatcttagg 4100

 gtggtgacag ctactggaac acttgcttta ggtgtcaaca tgccttgtaa 4150

 atctgtggtt tttgctcaaa actcagtcta tctggatgcg ttgaattata 4200

 gacagatgtc tggccgtgct ggaagaagag gtcaagacct gatgggagat 4250

 gtatatttct ttgatattcc attccccaaa ataggaaaac tcataaaatc 4300

 caatgttcct gagctgagag gacacttccc tctcagcata accctggtcc 4350

 tgcgactcat gctgctggct tccaagggag atgacccaga ggataccaag 4400

 gcaaaggtgc tatcagtgct aaagcattca ttgctgtcct tcaagcaacc 4450

 cagagtcatg gacatgttaa aactttactt cctgttttct ttgcagttcc 4500

 tggtgaaaga gggctattta gatcaagaag gtaatcctat ggggtttgct 4550

 ggacttgtat cacatttgca ttatcatgaa ccttctaatc ttgtttttgt 4600

 cagttttctt gtaaatggac tcttccatga tctctgtcag ccaaccagga 4650

 aaggctcaaa acatttttct caagacgtta tggaaaagct agtattagta 4700

 ttggcacatc tctttggaag aagatatttt ccaccaaagt tccaagatgc 4750

 acacttcgag ttttatcaat caaaggtgtt ccttgatgat ctccctgagg 4800

 attttagtga tgctttagat gaatataaca tgaaaattat ggaggacttt 4850

 accactttcc tacgaattgt ttccaaactg gctgatatga atcaggaata 4900

 tcaactccca ttgtcaaaaa tcaaattcac aggtaaagaa tgtgaagact 4950

 ctcaactcgt atctcatttg atgagctgca aggaaggaag agtagcaatt 5000

 tcaccatttg tttgtctgtc tgggaacttt gatgatgatt tgcttcgact 5050

 agaaactcca aaccatgtta ctctaggcac aatcggtgtc aatcgctctc 5100

 aggctccagt gctgttgtca cagaaatttg ataaccgagg aaggaaaatg 5150

 tcgcttaatg cctatgcact ggatttctac aaacatggtt ccttgatagg 5200

 attagtccag gataacagga tgaatgaagg agatgcttat tatttgttga 5250

 aggattttgc actcaccatt aaatctatca gtgtttcctt gcgtgagcta 5300

 tgtgaaaatg aagacgacaa cgttgtctta gcctttgaac aactgagtac 5350

 aactttttgg gaaaagttaa acaaagtcta aaaacaaagt ctatgcaaac 5400

 cacttaaaaa taattccata gtagtttttc aggtcacgtt tttgattctt 5450

 atgcttcttg ccagaaatac attatgataa agtggaaata cattacgatg 5500

 aagtggaaag agcaaacact ttggaatcaa acagagttgc aatcaaacct 5550

 gcaatgttct gtcatgaata ctcacaaatt atttagtata cctgaatctt 5600

 ggtttctttt tataactgag taataatggt tacatctcag gtagtttgag 5650

 gattgactaa aaaaatgcga gaatgttgta tgtgactgaa taacaatttt 5700

 tactctgcga agccaaagta aatataatat tatcagtaac tttatcccca 5750

 gtgtcagtat ttataaaatg tttattaagg ctagaaaaaa tgaatacaat 5800

 atcctgaagg tgaaatatat tctcttcaat tagcataaat atgatttaca 5850

 taagttagct atacagctat tgagatagta ctttctagta aacttaaact 5900

 actttttaaa catacatttt gtgatgattt aacaaaaata tagagaatga 5950

 tttgctttat tgtaattgta tataagtgac tggaaaagca caaagaaata 6000

 aagtgggttc gatctgttaa ataaaaaaaa aaaaaa 6036

<210> 6107
<211> 1712
<212> PRT
<213> Homo sapien

<400> 6107
 Met Glu Arg Asn Val Leu Thr Thr Phe Ser Gln Glu Met Ser Gln
   1               5                  10                  15

 Leu Ile Leu Asn Glu Met Pro Lys Ala Glu Tyr Ser Ser Leu Phe
                  20                  25                  30

 Asn Asp Phe Val Glu Ser Glu Phe Phe Leu Ile Asp Gly Asp Ser
                  35                  40                  45

 Leu Leu Ile Thr Cys Ile Cys Glu Ile Ser Phe Lys Pro Gly Gln
                  50                  55                  60

 Asn Leu His Phe Phe Tyr Leu Val Glu Arg Tyr Leu Val Asp Leu
                  65                  70                  75

 Ile Ser Lys Gly Gly Gln Phe Thr Ile Val Phe Phe Lys Asp Ala
                  80                  85                  90

 Glu Tyr Ala Tyr Phe Asn Phe Pro Glu Leu Leu Ser Leu Arg Thr
                  95                 100                 105

 Ala Leu Ile Leu His Leu Gln Lys Asn Thr Thr Ile Asp Val Arg
                 110                 115                 120

 Thr Thr Phe Ser Arg Cys Leu Ser Lys Glu Trp Gly Ser Phe Leu
                 125                 130                 135

 Glu Glu Ser Tyr Pro Tyr Phe Leu Ile Val Ala Asp Glu Gly Leu
                 140                 145                 150

 Asn Asp Leu Gln Thr Gln Leu Phe Asn Phe Leu Ile Ile His Ser
                 155                 160                 165

 Trp Ala Arg Lys Val Asn Val Val Leu Ser Ser Gly Gln Glu Ser
                 170                 175                 180

 Asp Val Leu Cys Leu Tyr Ala Tyr Leu Leu Pro Ser Met Tyr Arg
                 185                 190                 195

 His Gln Ile Phe Ser Trp Lys Asn Lys Gln Asn Ile Lys Asp Ala
                 200                 205                 210

 Tyr Thr Thr Leu Leu Asn Gln Leu Glu Arg Phe Lys Leu Ser Ala
                 215                 220                 225

 Leu Ala Pro Leu Phe Gly Ser Leu Lys Trp Asn Asn Ile Thr Glu
                 230                 235                 240

 Glu Ala His Lys Thr Val Ser Leu Leu Thr Gln Val Trp Pro Glu
                 245                 250                 255

 Gly Ser Asp Ile Arg Arg Val Phe Cys Val Thr Ser Cys Ser Leu
                 260                 265                 270

 Ser Leu Arg Met Tyr His Arg Phe Leu Gly Asn Arg Glu Pro Ser
                 275                 280                 285

 Ser Gly Gln Glu Thr Glu Ile Gln Gln Val Asn Ser Asn Cys Leu
                 290                 295                 300

 Thr Leu Gln Glu Met Glu Asp Leu Cys Lys Leu His Cys Leu Thr
                 305                 310                 315

 Val Val Phe Leu Leu His Leu Pro Leu Ser Gln Arg Ala Cys Ala
                 320                 325                 330

 Arg Val Ile Thr Ser His Trp Ala Glu Asp Met Lys Pro Leu Leu
                 335                 340                 345

 Gln Met Lys Lys Trp Cys Glu Tyr Phe Ile Leu Arg Asn Ile His
                 350                 355                 360

 Thr Phe Glu Phe Trp Asn Leu Asn Leu Ile His Leu Ser Asp Leu
                 365                 370                 375

 Asn Asp Glu Leu Leu Leu Lys Asn Ile Ala Phe Tyr Tyr Glu Asn
                 380                 385                 390

 Glu Asn Val Lys Gly Leu His Leu Asn Leu Gly Asp Thr Ile Met
                 395                 400                 405

 Lys Asp Tyr Glu Tyr Leu Trp Asn Thr Val Ser Lys Leu Val Arg
                 410                 415                 420

 Asp Phe Glu Val Gly Gln Pro Phe Pro Leu Arg Thr Thr Lys Val
                 425                 430                 435

 Cys Phe Leu Gly Lys Lys Pro Ser Pro Ile Lys Asp Ser Ser Asn
                 440                 445                 450

 Glu Met Val Pro Asn Leu Gly Phe Ile Pro Thr Ser Ser Phe Val
                 455                 460                 465

 Val Asp Lys Phe Ala Gly Asp Ile Leu Lys Asp Leu Pro Phe Leu
                 470                 475                 480

 Lys Ser Asp Asp Pro Ile Val Thr Ser Leu Val Lys Gln Lys Glu
                 485                 490                 495

 Phe Asp Glu Leu Val His Trp His Ser His Lys Pro Leu Ser Asp
                 500                 505                 510

 Asp Tyr Asp Arg Ser Arg Cys Gln Phe Asp Glu Lys Ser Arg Asp
                 515                 520                 525

 Pro Arg Val Leu Arg Ser Val Gln Lys Tyr His Val Phe Gln Arg
                 530                 535                 540

 Phe Tyr Gly Asn Ser Leu Glu Thr Val Ser Ser Lys Ile Ile Val
                 545                 550                 555

 Thr Gln Thr Ile Lys Ser Lys Lys Asp Phe Ser Gly Pro Lys Ser
                 560                 565                 570

 Lys Lys Ala His Glu Thr Lys Ala Glu Ile Ile Ala Arg Glu Asn
                 575                 580                 585

 Lys Lys Arg Leu Phe Ala Arg Glu Glu Gln Lys Glu Glu Gln Lys
                 590                 595                 600

 Trp Asn Ala Leu Ser Phe Ser Ile Glu Glu Gln Leu Lys Glu Asn
                 605                 610                 615

 Leu His Ser Gly Ile Lys Ser Leu Glu Asp Phe Leu Lys Ser Cys
                 620                 625                 630

 Lys Ser Ser Cys Val Lys Leu Gln Val Glu Met Val Gly Leu Thr
                 635                 640                 645

 Ala Cys Leu Lys Ala Trp Lys Glu His Cys Arg Ser Glu Glu Gly
                 650                 655                 660

 Lys Thr Thr Lys Asp Leu Ser Ile Ala Val Gln Val Met Lys Arg
                 665                 670                 675

 Ile His Ser Leu Met Glu Lys Tyr Ser Glu Leu Leu Gln Glu Asp
                 680                 685                 690

 Asp Arg Gln Leu Ile Ala Arg Cys Leu Lys Tyr Leu Gly Phe Asp
                 695                 700                 705

 Glu Leu Ala Ser Ser Leu His Pro Ala Gln Asp Ala Glu Asn Asp
                 710                 715                 720

 Val Lys Val Lys Lys Arg Asn Lys Tyr Ser Ile Gly Ile Gly Pro
                 725                 730                 735

 Ala Arg Phe Gln Leu Gln Tyr Met Gly His Tyr Leu Ile Arg Asp
                 740                 745                 750

 Glu Arg Lys Asp Pro Asp Pro Arg Val Gln Asp Phe Ile Pro Asp
                 755                 760                 765

 Thr Trp Gln Arg Glu Leu Leu Asp Val Val Asp Lys Asn Glu Ser
                 770                 775                 780

 Ala Val Ile Val Ala Pro Thr Ser Ser Gly Lys Thr Tyr Ala Ser
                 785                 790                 795

 Tyr Tyr Cys Met Glu Lys Val Leu Lys Glu Ser Asp Asp Gly Val
                 800                 805                 810

 Val Val Tyr Val Ala Pro Thr Lys Ala Leu Val Asn Gln Val Ala
                 815                 820                 825

 Ala Thr Val Gln Asn Arg Phe Thr Lys Asn Leu Pro Ser Gly Glu
                 830                 835                 840

 Val Leu Cys Gly Val Phe Thr Arg Glu Tyr Arg His Asp Ala Leu
                 845                 850                 855

 Asn Cys Gln Val Leu Ile Thr Val Pro Ala Cys Phe Glu Ile Leu
                 860                 865                 870

 Leu Leu Ala Pro His Arg Gln Asn Trp Val Lys Lys Ile Arg Tyr
                 875                 880                 885

 Val Ile Phe Asp Glu Val His Cys Leu Gly Gly Glu Ile Gly Ala
                 890                 895                 900

 Glu Ile Trp Glu His Leu Leu Val Met Ile Arg Cys Pro Phe Leu
                 905                 910                 915

 Ala Leu Ser Ala Thr Ile Ser Asn Pro Glu His Leu Thr Glu Trp
                 920                 925                 930

 Leu Gln Ser Val Lys Trp Tyr Trp Lys Gln Glu Asp Lys Ile Ile
                 935                 940                 945

 Glu Asn Asn Thr Ala Ser Lys Arg His Val Gly Arg Gln Ala Gly
                 950                 955                 960

 Phe Pro Lys Asp Tyr Leu Gln Val Lys Gln Ser Tyr Lys Val Arg
                 965                 970                 975

 Leu Val Leu Tyr Gly Glu Arg Tyr Asn Asp Leu Glu Lys His Val
                 980                 985                 990

 Cys Ser Ile Lys His Gly Asp Ile His Phe Asp His Phe His Pro
                 995                1000                1005

 Cys Ala Ala Leu Thr Thr Asp His Ile Glu Arg Tyr Gly Phe Pro
                1010                1015                1020

 Pro Asp Leu Thr Leu Ser Pro Arg Glu Ser Ile Gln Leu Tyr Asp
                1025                1030                1035

 Ala Met Phe Gln Ile Trp Lys Ser Trp Pro Arg Ala Gln Glu Leu
                1040                1045                1050

 Cys Pro Glu Asn Phe Ile His Phe Asn Asn Lys Leu Val Ile Lys
                1055                1060                1065

 Lys Met Asp Ala Arg Lys Tyr Glu Glu Ser Leu Lys Ala Glu Leu
                1070                1075                1080

 Thr Ser Trp Ile Lys Asn Gly Asn Val Glu Gln Ala Arg Met Val
                1085                1090                1095

 Leu Gln Asn Leu Ser Pro Glu Ala Asp Leu Ser Pro Glu Asn Met
                1100                1105                1110

 Ile Thr Met Phe Pro Leu Leu Val Glu Lys Leu Arg Lys Met Glu
                1115                1120                1125

 Lys Leu Pro Ala Leu Phe Phe Leu Phe Lys Leu Gly Ala Val Glu
                1130                1135                1140

 Asn Ala Ala Glu Ser Val Ser Thr Phe Leu Lys Lys Lys Gln Glu
                1145                1150                1155

 Thr Lys Arg Pro Pro Lys Ala Asp Lys Glu Ala His Val Met Ala
                1160                1165                1170

 Asn Lys Leu Arg Lys Val Lys Lys Ser Ile Glu Lys Gln Lys Ile
                1175                1180                1185

 Ile Asp Glu Lys Ser Gln Lys Lys Thr Arg Asn Val Asp Gln Ser
                1190                1195                1200

 Leu Ile His Glu Ala Glu His Asp Asn Leu Val Lys Cys Leu Glu
                1205                1210                1215

 Lys Asn Leu Glu Ile Pro Gln Asp Cys Thr Tyr Ala Asp Gln Lys
                1220                1225                1230

 Ala Val Asp Thr Glu Thr Leu Gln Lys Val Phe Gly Arg Val Lys
                1235                1240                1245

 Phe Glu Arg Lys Gly Glu Glu Leu Lys Ala Leu Ala Glu Arg Gly
                1250                1255                1260

 Ile Gly Tyr His His Ser Ala Met Ser Phe Lys Glu Lys Gln Leu
                1265                1270                1275

 Val Glu Ile Leu Phe Arg Lys Gly Tyr Leu Arg Val Val Thr Ala
                1280                1285                1290

 Thr Gly Thr Leu Ala Leu Gly Val Asn Met Pro Cys Lys Ser Val
                1295                1300                1305

 Val Phe Ala Gln Asn Ser Val Tyr Leu Asp Ala Leu Asn Tyr Arg
                1310                1315                1320

 Gln Met Ser Gly Arg Ala Gly Arg Arg Gly Gln Asp Leu Met Gly
                1325                1330                1335

 Asp Val Tyr Phe Phe Asp Ile Pro Phe Pro Lys Ile Gly Lys Leu
                1340                1345                1350

 Ile Lys Ser Asn Val Pro Glu Leu Arg Gly His Phe Pro Leu Ser
                1355                1360                1365

 Ile Thr Leu Val Leu Arg Leu Met Leu Leu Ala Ser Lys Gly Asp
                1370                1375                1380

 Asp Pro Glu Asp Thr Lys Ala Lys Val Leu Ser Val Leu Lys His
                1385                1390                1395

 Ser Leu Leu Ser Phe Lys Gln Pro Arg Val Met Asp Met Leu Lys
                1400                1405                1410

 Leu Tyr Phe Leu Phe Ser Leu Gln Phe Leu Val Lys Glu Gly Tyr
                1415                1420                1425

 Leu Asp Gln Glu Gly Asn Pro Met Gly Phe Ala Gly Leu Val Ser
                1430                1435                1440

 His Leu His Tyr His Glu Pro Ser Asn Leu Val Phe Val Ser Phe
                1445                1450                1455

 Leu Val Asn Gly Leu Phe His Asp Leu Cys Gln Pro Thr Arg Lys
                1460                1465                1470

 Gly Ser Lys His Phe Ser Gln Asp Val Met Glu Lys Leu Val Leu
                1475                1480                1485

 Val Leu Ala His Leu Phe Gly Arg Arg Tyr Phe Pro Pro Lys Phe
                1490                1495                1500

 Gln Asp Ala His Phe Glu Phe Tyr Gln Ser Lys Val Phe Leu Asp
                1505                1510                1515

 Asp Leu Pro Glu Asp Phe Ser Asp Ala Leu Asp Glu Tyr Asn Met
                1520                1525                1530

 Lys Ile Met Glu Asp Phe Thr Thr Phe Leu Arg Ile Val Ser Lys
                1535                1540                1545

 Leu Ala Asp Met Asn Gln Glu Tyr Gln Leu Pro Leu Ser Lys Ile
                1550                1555                1560

 Lys Phe Thr Gly Lys Glu Cys Glu Asp Ser Gln Leu Val Ser His
                1565                1570                1575

 Leu Met Ser Cys Lys Glu Gly Arg Val Ala Ile Ser Pro Phe Val
                1580                1585                1590

 Cys Leu Ser Gly Asn Phe Asp Asp Asp Leu Leu Arg Leu Glu Thr
                1595                1600                1605

 Pro Asn His Val Thr Leu Gly Thr Ile Gly Val Asn Arg Ser Gln
                1610                1615                1620

 Ala Pro Val Leu Leu Ser Gln Lys Phe Asp Asn Arg Gly Arg Lys
                1625                1630                1635

 Met Ser Leu Asn Ala Tyr Ala Leu Asp Phe Tyr Lys His Gly Ser
                1640                1645                1650

 Leu Ile Gly Leu Val Gln Asp Asn Arg Met Asn Glu Gly Asp Ala
                1655                1660                1665

 Tyr Tyr Leu Leu Lys Asp Phe Ala Leu Thr Ile Lys Ser Ile Ser
                1670                1675                1680

 Val Ser Leu Arg Glu Leu Cys Glu Asn Glu Asp Asp Asn Val Val
                1685                1690                1695

 Leu Ala Phe Glu Gln Leu Ser Thr Thr Phe Trp Glu Lys Leu Asn
                1700                1705                1710

 Lys Val


<210> 6108
<211> 3502
<212> DNA
<213> Homo sapien

<400> 6108
 gcgcgcagct ggttcccgct ctgcagcgca acgcctgagg cagtgggcgc 50

 gctcagtccc gggaccaggc gttctctcct ctcgcctctg ggcctgggac 100

 ccgcaaagcg gcgatggagc ggaggtcgcg gaggaagtcg cggcgcaacg 150

 ggcgctcgac cgcgggcaag gccgccgcga cccagcccgc gaagtctccg 200

 ggcgcacagc tctggctctt tcccagcgcc gcgggcctcc accgcgcgct 250

 gctccggagg gtggaggtga cgcgccaact ctgctgctcg ccggggcgcc 300

 tcgcggtctt ggaacgcggc ggggcgggcg tccaggttca ccagctgctc 350

 gccgggagcg gcggcgcccg gacgccgaaa tgcattaaat taggaaaaaa 400

 catgaagata cattccgtgg accaaggagc agagcacatg ctgattctct 450

 catcagatgg aaaaccattt gagtatgaca actatagcat gaaacatcta 500

 aggtttgaaa gcattttaca agaaaaaaaa ataattcaga tcacatgtgg 550

 agattaccat tctcttgcac tctcaaaagg cggtgagctt tttgcctggg 600

 gacagaacct gcatgggcag cttggagttg gaaggaaatt tccctcaacc 650

 accacaccac agattgtgga gcacctcgca ggagtaccct tggctcagat 700

 ttctgccgga gaagcccaca gcatggcctt atccatgtct ggcaacattt 750

 attcatgggg aaaaaatgaa tgtggacaac taggcctggg ccacactgag 800

 agtaaagatg atccatccct tattgaagga ctagacaatc agaaagttga 850

 atttgtcgct tgtggtggct ctcacagtgc cctactcaca caggatgggc 900

 tgctgtttac tttcggtgct ggaaaacatg ggcaacttgg tcataattca 950

 acacagaatg agctaagacc ctgtttggtg gctgagcttg ttgggtatag 1000

 agtgactcag atagcatgtg gaaggtggca cacacttgcc tatgtttctg 1050

 atttgggaaa ggtcttttcc tttggttctg gaaaagatgg acaactggga 1100

 aatggtggaa cacgtgacca gctgatgccg cttccagtga aagtatcatc 1150

 aagtgaagaa ctcaaacttg aaagccatac ctcagaaaag gagttaataa 1200

 tgattgctgg agggaatcaa agcattttgc tctggataaa gaaagagaat 1250

 tcatatgtta atctgaagag gacaattcct actctgaatg aagggactgt 1300

 aaagagatgg attgctgatg tggagactaa acggtggcag agcacaaaaa 1350

 gggaaatcca agagatattt tcatctcctg cttgtctaac tggaagtttt 1400

 ttaaggaaaa gaagaactac agaaatgatg cctgtttatt tggacttaaa 1450

 taaagcaaga aacatcttca gggagttaac ccaaaaggac tggattacta 1500

 acatgataac cacctgcctc aaagataatc tgctcaaaag acttccattt 1550

 cattctccac cccaagaagc tttagaaatt ttcttccttc tcccagaatg 1600

 tcctgtgatg catatttcca acaactggga gagccttgtg gttccatttg 1650

 caaaggttgt ttgtaaaatg agtgaccagt cttcactggt tctggaagag 1700

 tattgggcaa ctctgcaaga atccactttc agcaaactgg tccagatgtt 1750

 taaaacagcc gtcatatgcc agttggatta ctgggatgaa agtgctgagg 1800

 agaatggtaa tgttcaagct ctcctagaaa tgttgaagaa gctgcacagg 1850

 gtaaaccagg tgaaatgtca actacctgaa agtattttcc aagtagacga 1900

 actcttgcac cgtctcaatt tttttgtaga agtatgcaga aggtacttgt 1950

 ggaaaatgac tgtggacgct tcagaaaatg tacaatgctg cgtcatattc 2000

 agtcactttc catttatctt taataatctg tcgaaaatta aactactaca 2050

 tacagacaca cttttaaaaa tagagagtaa aaaacataaa gcttatctta 2100

 ggtcggcagc aattgaggaa gaaagagagt ctgaattcgc tttgaggccc 2150

 acgtttgatc taacagtcag aaggaatcac ttgattgagg atgttttgaa 2200

 tcagctaagt caatttgaga atgaagacct gaggaaagag ttatgggttt 2250

 catttagtgg agaaattggg tatgacctcg gaggagtcaa gaaagagttc 2300

 ttctactgtc tgtttgcaga gatgatccag ccggaatatg ggatgttcat 2350

 gtatcctgaa ggggcttcct gcatgtggtt tcctgtcaag cctaaatttg 2400

 agaagaaaag atacttcttt tttggggttc tatgtggact ttccctgttc 2450

 aattgcaatg ttgccaacct ccctttccca ctggcactgt ttaagaaact 2500

 tttggaccaa atgccatcat tggaagactt gaaagaactc agtcctgatt 2550

 tgggaaagaa tttgcaaaca cttctggatg atgaaggtga taactttgag 2600

 gaagtatttt acatccattt taatgtgcac tgggacagaa acgacacaaa 2650

 cttaattcct aatggaagta gcataactgt caaccagact aacaagagag 2700

 actatgtttc taagtatatc aattacattt tcaacgactc tgtaaaggcg 2750

 gtttatgaag aatttcggag aggattttat aaaatgtgcg acgaagacat 2800

 tatcaaatta ttccaccccg aagaactgaa ggatgtgatt gttggaaata 2850

 cagattatga ttggaaaaca tttgaaaaga atgcacgtta tgaaccagga 2900

 tataacagtt cacatcccac catagtgatg ttttggaagg ctttccacaa 2950

 attgactctg gaagaaaaga aaaaattcct tgtatttctt acaggaactg 3000

 acagactaca aatgaaagat ttaaataata tgaaaataac attttgctgt 3050

 cctgaaagtt ggaatgaaag agaccctata agagcactga catgtttcag 3100

 tgtcctcttc ctccctaaat attctacaat ggaaacagtt gaagaagcgc 3150

 ttcaagaagc catcaacaac aacagaggat ttggctgacc agcttgcttg 3200

 tccaacagcc ttattttgtt gttgttatcg ttgttgttgt tgttgttgtt 3250

 gttgtttctc tactttgttt tgttttaggc ttttagcagc ctgaagccat 3300

 ggtttttcat ttctgtctct agtgataagc aggaaagagg gatgaagaag 3350

 agggtttact ggccggttag aacccgtgac tgtattctct cccttggata 3400

 cccctatgcc tacatcatat tccttacctc ttttgggaaa tatttttcaa 3450

 aaataaaata accgaaaaac taaaaaaaga aaaaaaaaaa aaaaaaaaaa 3500

 aa 3502

<210> 6109
<211> 1024
<212> PRT
<213> Homo sapien

<400> 6109
 Met Glu Arg Arg Ser Arg Arg Lys Ser Arg Arg Asn Gly Arg Ser
   1               5                  10                  15

 Thr Ala Gly Lys Ala Ala Ala Thr Gln Pro Ala Lys Ser Pro Gly
                  20                  25                  30

 Ala Gln Leu Trp Leu Phe Pro Ser Ala Ala Gly Leu His Arg Ala
                  35                  40                  45

 Leu Leu Arg Arg Val Glu Val Thr Arg Gln Leu Cys Cys Ser Pro
                  50                  55                  60

 Gly Arg Leu Ala Val Leu Glu Arg Gly Gly Ala Gly Val Gln Val
                  65                  70                  75

 His Gln Leu Leu Ala Gly Ser Gly Gly Ala Arg Thr Pro Lys Cys
                  80                  85                  90

 Ile Lys Leu Gly Lys Asn Met Lys Ile His Ser Val Asp Gln Gly
                  95                 100                 105

 Ala Glu His Met Leu Ile Leu Ser Ser Asp Gly Lys Pro Phe Glu
                 110                 115                 120

 Tyr Asp Asn Tyr Ser Met Lys His Leu Arg Phe Glu Ser Ile Leu
                 125                 130                 135

 Gln Glu Lys Lys Ile Ile Gln Ile Thr Cys Gly Asp Tyr His Ser
                 140                 145                 150

 Leu Ala Leu Ser Lys Gly Gly Glu Leu Phe Ala Trp Gly Gln Asn
                 155                 160                 165

 Leu His Gly Gln Leu Gly Val Gly Arg Lys Phe Pro Ser Thr Thr
                 170                 175                 180

 Thr Pro Gln Ile Val Glu His Leu Ala Gly Val Pro Leu Ala Gln
                 185                 190                 195

 Ile Ser Ala Gly Glu Ala His Ser Met Ala Leu Ser Met Ser Gly
                 200                 205                 210

 Asn Ile Tyr Ser Trp Gly Lys Asn Glu Cys Gly Gln Leu Gly Leu
                 215                 220                 225

 Gly His Thr Glu Ser Lys Asp Asp Pro Ser Leu Ile Glu Gly Leu
                 230                 235                 240

 Asp Asn Gln Lys Val Glu Phe Val Ala Cys Gly Gly Ser His Ser
                 245                 250                 255

 Ala Leu Leu Thr Gln Asp Gly Leu Leu Phe Thr Phe Gly Ala Gly
                 260                 265                 270

 Lys His Gly Gln Leu Gly His Asn Ser Thr Gln Asn Glu Leu Arg
                 275                 280                 285

 Pro Cys Leu Val Ala Glu Leu Val Gly Tyr Arg Val Thr Gln Ile
                 290                 295                 300

 Ala Cys Gly Arg Trp His Thr Leu Ala Tyr Val Ser Asp Leu Gly
                 305                 310                 315

 Lys Val Phe Ser Phe Gly Ser Gly Lys Asp Gly Gln Leu Gly Asn
                 320                 325                 330

 Gly Gly Thr Arg Asp Gln Leu Met Pro Leu Pro Val Lys Val Ser
                 335                 340                 345

 Ser Ser Glu Glu Leu Lys Leu Glu Ser His Thr Ser Glu Lys Glu
                 350                 355                 360

 Leu Ile Met Ile Ala Gly Gly Asn Gln Ser Ile Leu Leu Trp Ile
                 365                 370                 375

 Lys Lys Glu Asn Ser Tyr Val Asn Leu Lys Arg Thr Ile Pro Thr
                 380                 385                 390

 Leu Asn Glu Gly Thr Val Lys Arg Trp Ile Ala Asp Val Glu Thr
                 395                 400                 405

 Lys Arg Trp Gln Ser Thr Lys Arg Glu Ile Gln Glu Ile Phe Ser
                 410                 415                 420

 Ser Pro Ala Cys Leu Thr Gly Ser Phe Leu Arg Lys Arg Arg Thr
                 425                 430                 435

 Thr Glu Met Met Pro Val Tyr Leu Asp Leu Asn Lys Ala Arg Asn
                 440                 445                 450

 Ile Phe Arg Glu Leu Thr Gln Lys Asp Trp Ile Thr Asn Met Ile
                 455                 460                 465

 Thr Thr Cys Leu Lys Asp Asn Leu Leu Lys Arg Leu Pro Phe His
                 470                 475                 480

 Ser Pro Pro Gln Glu Ala Leu Glu Ile Phe Phe Leu Leu Pro Glu
                 485                 490                 495

 Cys Pro Val Met His Ile Ser Asn Asn Trp Glu Ser Leu Val Val
                 500                 505                 510

 Pro Phe Ala Lys Val Val Cys Lys Met Ser Asp Gln Ser Ser Leu
                 515                 520                 525

 Val Leu Glu Glu Tyr Trp Ala Thr Leu Gln Glu Ser Thr Phe Ser
                 530                 535                 540

 Lys Leu Val Gln Met Phe Lys Thr Ala Val Ile Cys Gln Leu Asp
                 545                 550                 555

 Tyr Trp Asp Glu Ser Ala Glu Glu Asn Gly Asn Val Gln Ala Leu
                 560                 565                 570

 Leu Glu Met Leu Lys Lys Leu His Arg Val Asn Gln Val Lys Cys
                 575                 580                 585

 Gln Leu Pro Glu Ser Ile Phe Gln Val Asp Glu Leu Leu His Arg
                 590                 595                 600

 Leu Asn Phe Phe Val Glu Val Cys Arg Arg Tyr Leu Trp Lys Met
                 605                 610                 615

 Thr Val Asp Ala Ser Glu Asn Val Gln Cys Cys Val Ile Phe Ser
                 620                 625                 630

 His Phe Pro Phe Ile Phe Asn Asn Leu Ser Lys Ile Lys Leu Leu
                 635                 640                 645

 His Thr Asp Thr Leu Leu Lys Ile Glu Ser Lys Lys His Lys Ala
                 650                 655                 660

 Tyr Leu Arg Ser Ala Ala Ile Glu Glu Glu Arg Glu Ser Glu Phe
                 665                 670                 675

 Ala Leu Arg Pro Thr Phe Asp Leu Thr Val Arg Arg Asn His Leu
                 680                 685                 690

 Ile Glu Asp Val Leu Asn Gln Leu Ser Gln Phe Glu Asn Glu Asp
                 695                 700                 705

 Leu Arg Lys Glu Leu Trp Val Ser Phe Ser Gly Glu Ile Gly Tyr
                 710                 715                 720

 Asp Leu Gly Gly Val Lys Lys Glu Phe Phe Tyr Cys Leu Phe Ala
                 725                 730                 735

 Glu Met Ile Gln Pro Glu Tyr Gly Met Phe Met Tyr Pro Glu Gly
                 740                 745                 750

 Ala Ser Cys Met Trp Phe Pro Val Lys Pro Lys Phe Glu Lys Lys
                 755                 760                 765

 Arg Tyr Phe Phe Phe Gly Val Leu Cys Gly Leu Ser Leu Phe Asn
                 770                 775                 780

 Cys Asn Val Ala Asn Leu Pro Phe Pro Leu Ala Leu Phe Lys Lys
                 785                 790                 795

 Leu Leu Asp Gln Met Pro Ser Leu Glu Asp Leu Lys Glu Leu Ser
                 800                 805                 810

 Pro Asp Leu Gly Lys Asn Leu Gln Thr Leu Leu Asp Asp Glu Gly
                 815                 820                 825

 Asp Asn Phe Glu Glu Val Phe Tyr Ile His Phe Asn Val His Trp
                 830                 835                 840

 Asp Arg Asn Asp Thr Asn Leu Ile Pro Asn Gly Ser Ser Ile Thr
                 845                 850                 855

 Val Asn Gln Thr Asn Lys Arg Asp Tyr Val Ser Lys Tyr Ile Asn
                 860                 865                 870

 Tyr Ile Phe Asn Asp Ser Val Lys Ala Val Tyr Glu Glu Phe Arg
                 875                 880                 885

 Arg Gly Phe Tyr Lys Met Cys Asp Glu Asp Ile Ile Lys Leu Phe
                 890                 895                 900

 His Pro Glu Glu Leu Lys Asp Val Ile Val Gly Asn Thr Asp Tyr
                 905                 910                 915

 Asp Trp Lys Thr Phe Glu Lys Asn Ala Arg Tyr Glu Pro Gly Tyr
                 920                 925                 930

 Asn Ser Ser His Pro Thr Ile Val Met Phe Trp Lys Ala Phe His
                 935                 940                 945

 Lys Leu Thr Leu Glu Glu Lys Lys Lys Phe Leu Val Phe Leu Thr
                 950                 955                 960

 Gly Thr Asp Arg Leu Gln Met Lys Asp Leu Asn Asn Met Lys Ile
                 965                 970                 975

 Thr Phe Cys Cys Pro Glu Ser Trp Asn Glu Arg Asp Pro Ile Arg
                 980                 985                 990

 Ala Leu Thr Cys Phe Ser Val Leu Phe Leu Pro Lys Tyr Ser Thr
                 995                1000                1005

 Met Glu Thr Val Glu Glu Ala Leu Gln Glu Ala Ile Asn Asn Asn
                1010                1015                1020

 Arg Gly Phe Gly


<210> 6110
<211> 2770
<212> DNA
<213> Homo sapien

<400> 6110
 gagtctggcc gcagtcgcgg cagtggtggc ttcccatccc caaaaggcgc 50

 cctccgactc cttgcgccgc actgctcgcc gggccagtcc ggaaacgggt 100

 cgtggagctc cgcaccactc ccgctggttc ccgaaggcag atcccttctc 150

 ccgagagttg cgagaaactt tcccttgtcc ccgacgctgc agcggctcgg 200

 gtaccgtggc agccgcaggt ttctgaaccc cgggccacgc tccccgcgcc 250

 tcggcttcgc gctcgtgtag atcgttccct ctctggttgc acgctgggga 300

 tcccggacct cgattctgcg ggcgagatgc ccctgggaca catcatgagg 350

 ctggacctgg agaaaattgc cctggagtac atcgtgccct gtctgcacga 400

 ggtgggcttc tgctacctgg acaacttcct gggcgaggtg gtgggcgact 450

 gcgtcctgga gcgcgtcaag cagctgcact gcaccggggc cctgcgggac 500

 ggccagctgg cggggccgcg cgccggcgtc tccaagcgac acctgcgggg 550

 cgaccagatc acgtggatcg ggggcaacga ggagggctgc gaggccatca 600

 gcttcctcct gtccctcatc gacaggctgg tcctctactg cgggagccgg 650

 ctgggcaaat actacgtcaa ggagaggtct aaggcaatgg tggcttgcta 700

 tccgggaaat ggaacaggtt atgttcgcca cgtggacaac cccaacggtg 750

 atggtcgctg catcacctgc atctactatc tgaacaagaa ttgggatgcc 800

 aagctacatg gtgggatcct gcggatattt ccagagggga aatcattcat 850

 agcagatgtg gagcccattt ttgacagact cctgttcttc tggtcagatc 900

 gtaggaaccc acacgaagtg cagccctctt acgcaaccag atatgctatg 950

 actgtctggt actttgatgc tgaagaaagg gcagaagcca aaaagaaatt 1000

 caggaattta actaggaaaa ctgaatctgc cctcactgaa gactgaccgt 1050

 gctctgaaat ctgctggcct tgttcatttt agtaacggtt cctgaattct 1100

 cttaaattct ttgagatcca aagatggcct cttcagtgac aacaatctcc 1150

 ctgctacttc ttgcatcctt cacatccctg tcttgtgtgt ggtacttcat 1200

 gttttcttgc caagactgtg ttgatcttca gatactctct ttgccagatg 1250

 aagttatttg ctaactccag aaattcctgc agacatccta ctcggccagc 1300

 ggtttacctg atagattcgg taatactatc aagagaagag cctaggagca 1350

 cagcgaggga atgaacctta cttgcacttt atgtatactt cctgatttga 1400

 aaggaggagg tttgaaaaga aaaaaatgga ggtggtagat gccacagaga 1450

 ggcatcacgg aagccttaac agcaggaaac agagaaattt gtgtcatctg 1500

 aacaatttcc agatgttctt aatccagggc tgttggggtt tctggagaat 1550

 tatcacaacc taatgacatt aatacctcta gaaagggctg ctgtcatagt 1600

 gaacaattta taagtgtccc atggggcaga cactcctttt ttcccagtcc 1650

 tgcaacctgg attttctgcc tcagctccat tttgctgaaa ataatgactt 1700

 tctgaataaa gatggcaaca caattttttc tccattttca gttcttacct 1750

 gggaacctaa ttccccagaa gctaaaaaac tagacattag ttgttttggt 1800

 tgctttgttg gaatggaatt taaatttaaa tgaaaggaaa aatatatccc 1850

 tggtagtttt gtgttaacca ctgataactg tggaaagagc taggtctact 1900

 gatatacaat aaacatgtgt gcatcttgaa caatttgaga ggggaggtgg 1950

 agttggaaat gtgggtgttc ctgttttttt tttttttttt tttttttttt 2000

 agttttcctt tttaatgagc tcacccttta acacaaaaaa agcagggtga 2050

 tgtattttaa aaaaggaagt ggaaataaaa aaatctcaaa gctatttgag 2100

 ttctcgtctg tccctagcag tctttcttca gctcacttgg ctctctagat 2150

 ccactgtggt tggcagtatg accagaatca tggaacttgc tagaactgtg 2200

 gaagcttcta ctcctgcagt aagcacagat cgcactgcct caataacttg 2250

 gtattgagca cgtattttgc aaaagctact tttcctagtt ttcagtatta 2300

 ctttcatgtt ttaaaaatcc ctttaatttc ttgcttgaaa atcccatgaa 2350

 cattaaagag ccagaaatat tttcctttgt tatgtacgga tatatatata 2400

 tatatagtct tccaagatag aagtttactt tttcctcttc tggttttgga 2450

 aaatttccag ataagacatg tcaccattaa ttctcaacga ctgctctatt 2500

 ttgttgtacg gtaatagtta tcaccttcta aattactatg taatttactc 2550

 acttattatg tttattgtct tgtatccttt ctctggagtg taagcacaat 2600

 gaagacagga attttgtata tttttaacca atgcaacata ctctcagcac 2650

 ctaaaatagt gccgggaaca tagtaagggc tcagtaaata cttgttgaat 2700

 aaactcagtc tcctacatta gcattctaaa aaaaaaaaaa aaaaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaag 2770

<210> 6111
<211> 239
<212> PRT
<213> Homo sapien

<400> 6111
 Met Pro Leu Gly His Ile Met Arg Leu Asp Leu Glu Lys Ile Ala
   1               5                  10                  15

 Leu Glu Tyr Ile Val Pro Cys Leu His Glu Val Gly Phe Cys Tyr
                  20                  25                  30

 Leu Asp Asn Phe Leu Gly Glu Val Val Gly Asp Cys Val Leu Glu
                  35                  40                  45

 Arg Val Lys Gln Leu His Cys Thr Gly Ala Leu Arg Asp Gly Gln
                  50                  55                  60

 Leu Ala Gly Pro Arg Ala Gly Val Ser Lys Arg His Leu Arg Gly
                  65                  70                  75

 Asp Gln Ile Thr Trp Ile Gly Gly Asn Glu Glu Gly Cys Glu Ala
                  80                  85                  90

 Ile Ser Phe Leu Leu Ser Leu Ile Asp Arg Leu Val Leu Tyr Cys
                  95                 100                 105

 Gly Ser Arg Leu Gly Lys Tyr Tyr Val Lys Glu Arg Ser Lys Ala
                 110                 115                 120

 Met Val Ala Cys Tyr Pro Gly Asn Gly Thr Gly Tyr Val Arg His
                 125                 130                 135

 Val Asp Asn Pro Asn Gly Asp Gly Arg Cys Ile Thr Cys Ile Tyr
                 140                 145                 150

 Tyr Leu Asn Lys Asn Trp Asp Ala Lys Leu His Gly Gly Ile Leu
                 155                 160                 165

 Arg Ile Phe Pro Glu Gly Lys Ser Phe Ile Ala Asp Val Glu Pro
                 170                 175                 180

 Ile Phe Asp Arg Leu Leu Phe Phe Trp Ser Asp Arg Arg Asn Pro
                 185                 190                 195

 His Glu Val Gln Pro Ser Tyr Ala Thr Arg Tyr Ala Met Thr Val
                 200                 205                 210

 Trp Tyr Phe Asp Ala Glu Glu Arg Ala Glu Ala Lys Lys Lys Phe
                 215                 220                 225

 Arg Asn Leu Thr Arg Lys Thr Glu Ser Ala Leu Thr Glu Asp
                 230                 235

<210> 6112
<211> 4221
<212> DNA
<213> Homo sapien

<400> 6112
 cagcggcagt ggagttcgct gcgcgctgtt gggggccacc tgtcttttcg 50

 cttgtgtccc tctttctagt gtcgcgctcg agtcccgacg ggccgctcca 100

 agcctcgaca tgtcgtacaa ctacgtggta acggcccaga agcccaccgc 150

 cgtgaacggc tgcgtgaccg gacactttac ttcggccgaa gacttaaacc 200

 tgttgattgc caaaaacacg agattagaga tctatgtggt caccgccgag 250

 gggcttcggc ccgtcaaaga ggtgggcatg tatgggaaga ttgcggtcat 300

 ggagcttttc aggcccaagg gggagagcaa ggacctgctg tttatcttga 350

 cagcgaagta caatgcctgc atcctggagt ataaacagag tggcgagagc 400

 attgacatca ttacgcgagc ccatggcaat gtccaggacc gcattggccg 450

 cccctcagag accggcatta ttggcatcat tgaccctgag tgccggatga 500

 ttggcctgcg tctctatgat ggccttttca aggttattcc actagatcgc 550

 gataataaag aactcaaggc cttcaacatc cgcctggagg agctgcatgt 600

 cattgatgtc aagttcctat atggttgcca agcacctact atttgctttg 650

 tctaccagga ccctcagggg cggcacgtaa aaacctatga ggtgtctctc 700

 cgagaaaagg aattcaataa gggcccttgg aaacaggaaa atgtcgaagc 750

 tgaagcttcc atggtgatcg cagtcccaga gccctttggg ggggccatca 800

 tcattggaca ggagtcaatc acctatcaca atggtgacaa atacctggct 850

 attgcccctc ctatcatcaa gcaaagcacg attgtgtgcc acaatcgagt 900

 ggaccctaat ggctcaagat acctgctggg agacatggaa ggccggctct 950

 tcatgctgct tttggagaag gaggaacaga tggatggcac cgtcactctc 1000

 aaggatctcc gtgtagaact ccttggagag acctctattg ctgagtgctt 1050

 gacatacctt gataatggtg ttgtgtttgt cgggtctcgc ctgggtgact 1100

 cccagcttgt gaagctcaac gttgacagta atgaacaagg ctcctatgta 1150

 gtggccatgg aaacctttac caacttagga cccattgtcg atatgtgcgt 1200

 ggtggacctg gagaggcagg ggcaggggca gctggtcact tgctctgggg 1250

 ctttcaagga aggttctttg cggatcatcc ggaatggaat tggaatccac 1300

 gagcatgcca gcattgactt accaggcatc aaaggattat ggccactgcg 1350

 gtctgaccct aatcgtgaga cttatgacac tttggtgctc tcttttgtgg 1400

 gccagacaag agttctcatg ttaaatggag aggaggtaga agaaaccgaa 1450

 ctgatgggtt tcgtggatga tcagcagact ttcttctgtg gcaacgtggc 1500

 tcatcagcag cttatccaga tcacttcagc atcggtgagg ttggtctctc 1550

 aagaacccaa agctctggtc agtgaatgga aggagcctca ggccaagaac 1600

 atcagtgtgg cctcctgcaa tagcagccag gtggtggtgg ctgtaggcag 1650

 ggccctctac tatctgcaga tccatcctca ggagctccgg cagatcagcc 1700

 acacagagat ggaacatgaa gtggcttgct tggacatcac cccattagga 1750

 gacagcaatg gactgtcccc tctttgtgcc attggcctct ggacggacat 1800

 ctcggctcgt atcttgaagt tgccctcttt tgaactactg cacaaggaga 1850

 tgctgggtgg agagatcatt cctcgctcca tcctgatgac cacctttgag 1900

 agtagccatt acctcctttg tgccttggga gatggagcgc ttttctactt 1950

 tgggctcaac attgagacag gtctgttgag cgaccgtaag aaggtgactt 2000

 tgggcaccca gcccaccgta ttgaggactt ttcgttctct ttctaccacc 2050

 aacgtctttg cttgttctga ccgccccact gtcatctata gcagcaacca 2100

 caaattggtc ttctcaaatg tcaacctcaa ggaagtgaac tacatgtgtc 2150

 ccctcaattc agatggctat cctgacagcc tggcgctggc caacaatagc 2200

 accctcacca ttggcaccat cgatgagatc cagaagctgc acattcgcac 2250

 agttcccctc tatgagtctc caaggaagat ctgctaccag gaagtgtccc 2300

 agtgtttcgg ggtcctctcc agccgcattg aagtccaaga cacgagtggg 2350

 ggcacgacag ccttgaggcc cagcgctagc acccaggctc tgtccagcag 2400

 tgtaagctcc agcaagctgt tctccagcag cactgctcct catgagacct 2450

 cctttggaga agaggtggag gtgcataacc tacttatcat tgaccaacac 2500

 acctttgaag tgcttcatgc ccaccagttt ctgcagaatg aatatgccct 2550

 cagtctggtt tcctgcaagc tgggcaaaga ccccaacact tacttcattg 2600

 tgggcacagc aatggtgtat cctgaagagg cagagcccaa gcagggtcgc 2650

 attgtggtct ttcagtattc ggatggaaaa ctacagactg tggctgaaaa 2700

 ggaagtgaaa ggggccgtgt actctatggt ggaatttaac gggaagctgt 2750

 tagccagcat caatagcacg gtgcggctct atgagtggac aacagagaag 2800

 gacgtgcgca ctgagtgcaa ccactacaac aacatcatgg ccctctacct 2850

 gaagaccaag ggcgacttca tcctggtggg cgaccttatg cgctcagtgc 2900

 tgctgcttgc ctacaagccc atggaaggaa actttgaaga gattgctcga 2950

 gactttaatc ccaactggat gagtgctgtg gaaatcttgg atgatgacaa 3000

 ttttctgggg gctgaaaatg cctttaactt gtttgtgtgt caaaaggata 3050

 gcgctgccac cactgacgag gagcggcagc acctccagga ggttggtctt 3100

 ttccacctgg gcgagtttgt caatgtcttt tgccacggct ctctggtaat 3150

 gcagaatctg ggtgagactt ccacccccac acaaggctcg gtgctcttcg 3200

 gcacggtcaa cggcatgata gggctggtga cctcactgtc agagagctgg 3250

 tacaacctcc tgctggacat gcagaatcga ctcaataaag tcatcaaaag 3300

 tgtggggaag atcgagcact ccttctggag atcctttcac accgagcgga 3350

 agacagaacc agccacaggt ttcatcgacg gtgacttgat tgagagtttc 3400

 ctggatatta gccgccccaa gatgcaggag gtggtggcaa acctacagta 3450

 tgacgatggc agcggtatga agcgagaggc cactgcagac gacctcatca 3500

 aggttgtgga ggagctaact cggatccatt agccaagggc agggggcccc 3550

 tttgctgacc ctccccaaag gctttgccct gctgccctcc ccctcctctc 3600

 caccatcgtc ttcttggcca tgggaggcct ttccctaagc cagctgcccc 3650

 cagagccaca gttcccctat gtggaagtgg ggcgggcttc atagagactt 3700

 gggaatgagc tgaaggtgaa acattttctc cctggatttt taccagtctc 3750

 acatgattcc agccatcacc ttagaccacc aagccttgat tggtgttgcc 3800

 agttgtcctc cttccgggga aggattttgc agttctttgg ctgaaaggaa 3850

 gctgtgcgtg tgtgtgtgtg tatgtgtgtg tgtgtatgtg tatctcacac 3900

 tcatgcattg tcctcttttt atttagattg gcagtgtagg gagttgtggg 3950

 tagtggggaa gagggttagg agggtttcat tgtctgtgaa gtgagacctt 4000

 ccttttactt ttcttctatt gcctctgaga gcatcaggcc tagaggcctg 4050

 actgccaagc catgggtagc ctgggtgtaa aacctggaga tggtggatga 4100

 tccccacgcc acagcccttt tgtctctgca aactgccttc ttcggaaaga 4150

 agaaggtggg aggatgtgaa ttgttagttt ctgagtttta ccaaataaag 4200

 tagaatataa gaagaaaaaa a 4221

<210> 6113
<211> 1140
<212> PRT
<213> Homo sapien

<400> 6113
 Met Ser Tyr Asn Tyr Val Val Thr Ala Gln Lys Pro Thr Ala Val
   1               5                  10                  15

 Asn Gly Cys Val Thr Gly His Phe Thr Ser Ala Glu Asp Leu Asn
                  20                  25                  30

 Leu Leu Ile Ala Lys Asn Thr Arg Leu Glu Ile Tyr Val Val Thr
                  35                  40                  45

 Ala Glu Gly Leu Arg Pro Val Lys Glu Val Gly Met Tyr Gly Lys
                  50                  55                  60

 Ile Ala Val Met Glu Leu Phe Arg Pro Lys Gly Glu Ser Lys Asp
                  65                  70                  75

 Leu Leu Phe Ile Leu Thr Ala Lys Tyr Asn Ala Cys Ile Leu Glu
                  80                  85                  90

 Tyr Lys Gln Ser Gly Glu Ser Ile Asp Ile Ile Thr Arg Ala His
                  95                 100                 105

 Gly Asn Val Gln Asp Arg Ile Gly Arg Pro Ser Glu Thr Gly Ile
                 110                 115                 120

 Ile Gly Ile Ile Asp Pro Glu Cys Arg Met Ile Gly Leu Arg Leu
                 125                 130                 135

 Tyr Asp Gly Leu Phe Lys Val Ile Pro Leu Asp Arg Asp Asn Lys
                 140                 145                 150

 Glu Leu Lys Ala Phe Asn Ile Arg Leu Glu Glu Leu His Val Ile
                 155                 160                 165

 Asp Val Lys Phe Leu Tyr Gly Cys Gln Ala Pro Thr Ile Cys Phe
                 170                 175                 180

 Val Tyr Gln Asp Pro Gln Gly Arg His Val Lys Thr Tyr Glu Val
                 185                 190                 195

 Ser Leu Arg Glu Lys Glu Phe Asn Lys Gly Pro Trp Lys Gln Glu
                 200                 205                 210

 Asn Val Glu Ala Glu Ala Ser Met Val Ile Ala Val Pro Glu Pro
                 215                 220                 225

 Phe Gly Gly Ala Ile Ile Ile Gly Gln Glu Ser Ile Thr Tyr His
                 230                 235                 240

 Asn Gly Asp Lys Tyr Leu Ala Ile Ala Pro Pro Ile Ile Lys Gln
                 245                 250                 255

 Ser Thr Ile Val Cys His Asn Arg Val Asp Pro Asn Gly Ser Arg
                 260                 265                 270

 Tyr Leu Leu Gly Asp Met Glu Gly Arg Leu Phe Met Leu Leu Leu
                 275                 280                 285

 Glu Lys Glu Glu Gln Met Asp Gly Thr Val Thr Leu Lys Asp Leu
                 290                 295                 300

 Arg Val Glu Leu Leu Gly Glu Thr Ser Ile Ala Glu Cys Leu Thr
                 305                 310                 315

 Tyr Leu Asp Asn Gly Val Val Phe Val Gly Ser Arg Leu Gly Asp
                 320                 325                 330

 Ser Gln Leu Val Lys Leu Asn Val Asp Ser Asn Glu Gln Gly Ser
                 335                 340                 345

 Tyr Val Val Ala Met Glu Thr Phe Thr Asn Leu Gly Pro Ile Val
                 350                 355                 360

 Asp Met Cys Val Val Asp Leu Glu Arg Gln Gly Gln Gly Gln Leu
                 365                 370                 375

 Val Thr Cys Ser Gly Ala Phe Lys Glu Gly Ser Leu Arg Ile Ile
                 380                 385                 390

 Arg Asn Gly Ile Gly Ile His Glu His Ala Ser Ile Asp Leu Pro
                 395                 400                 405

 Gly Ile Lys Gly Leu Trp Pro Leu Arg Ser Asp Pro Asn Arg Glu
                 410                 415                 420

 Thr Tyr Asp Thr Leu Val Leu Ser Phe Val Gly Gln Thr Arg Val
                 425                 430                 435

 Leu Met Leu Asn Gly Glu Glu Val Glu Glu Thr Glu Leu Met Gly
                 440                 445                 450

 Phe Val Asp Asp Gln Gln Thr Phe Phe Cys Gly Asn Val Ala His
                 455                 460                 465

 Gln Gln Leu Ile Gln Ile Thr Ser Ala Ser Val Arg Leu Val Ser
                 470                 475                 480

 Gln Glu Pro Lys Ala Leu Val Ser Glu Trp Lys Glu Pro Gln Ala
                 485                 490                 495

 Lys Asn Ile Ser Val Ala Ser Cys Asn Ser Ser Gln Val Val Val
                 500                 505                 510

 Ala Val Gly Arg Ala Leu Tyr Tyr Leu Gln Ile His Pro Gln Glu
                 515                 520                 525

 Leu Arg Gln Ile Ser His Thr Glu Met Glu His Glu Val Ala Cys
                 530                 535                 540

 Leu Asp Ile Thr Pro Leu Gly Asp Ser Asn Gly Leu Ser Pro Leu
                 545                 550                 555

 Cys Ala Ile Gly Leu Trp Thr Asp Ile Ser Ala Arg Ile Leu Lys
                 560                 565                 570

 Leu Pro Ser Phe Glu Leu Leu His Lys Glu Met Leu Gly Gly Glu
                 575                 580                 585

 Ile Ile Pro Arg Ser Ile Leu Met Thr Thr Phe Glu Ser Ser His
                 590                 595                 600

 Tyr Leu Leu Cys Ala Leu Gly Asp Gly Ala Leu Phe Tyr Phe Gly
                 605                 610                 615

 Leu Asn Ile Glu Thr Gly Leu Leu Ser Asp Arg Lys Lys Val Thr
                 620                 625                 630

 Leu Gly Thr Gln Pro Thr Val Leu Arg Thr Phe Arg Ser Leu Ser
                 635                 640                 645

 Thr Thr Asn Val Phe Ala Cys Ser Asp Arg Pro Thr Val Ile Tyr
                 650                 655                 660

 Ser Ser Asn His Lys Leu Val Phe Ser Asn Val Asn Leu Lys Glu
                 665                 670                 675

 Val Asn Tyr Met Cys Pro Leu Asn Ser Asp Gly Tyr Pro Asp Ser
                 680                 685                 690

 Leu Ala Leu Ala Asn Asn Ser Thr Leu Thr Ile Gly Thr Ile Asp
                 695                 700                 705

 Glu Ile Gln Lys Leu His Ile Arg Thr Val Pro Leu Tyr Glu Ser
                 710                 715                 720

 Pro Arg Lys Ile Cys Tyr Gln Glu Val Ser Gln Cys Phe Gly Val
                 725                 730                 735

 Leu Ser Ser Arg Ile Glu Val Gln Asp Thr Ser Gly Gly Thr Thr
                 740                 745                 750

 Ala Leu Arg Pro Ser Ala Ser Thr Gln Ala Leu Ser Ser Ser Val
                 755                 760                 765

 Ser Ser Ser Lys Leu Phe Ser Ser Ser Thr Ala Pro His Glu Thr
                 770                 775                 780

 Ser Phe Gly Glu Glu Val Glu Val His Asn Leu Leu Ile Ile Asp
                 785                 790                 795

 Gln His Thr Phe Glu Val Leu His Ala His Gln Phe Leu Gln Asn
                 800                 805                 810

 Glu Tyr Ala Leu Ser Leu Val Ser Cys Lys Leu Gly Lys Asp Pro
                 815                 820                 825

 Asn Thr Tyr Phe Ile Val Gly Thr Ala Met Val Tyr Pro Glu Glu
                 830                 835                 840

 Ala Glu Pro Lys Gln Gly Arg Ile Val Val Phe Gln Tyr Ser Asp
                 845                 850                 855

 Gly Lys Leu Gln Thr Val Ala Glu Lys Glu Val Lys Gly Ala Val
                 860                 865                 870

 Tyr Ser Met Val Glu Phe Asn Gly Lys Leu Leu Ala Ser Ile Asn
                 875                 880                 885

 Ser Thr Val Arg Leu Tyr Glu Trp Thr Thr Glu Lys Asp Val Arg
                 890                 895                 900

 Thr Glu Cys Asn His Tyr Asn Asn Ile Met Ala Leu Tyr Leu Lys
                 905                 910                 915

 Thr Lys Gly Asp Phe Ile Leu Val Gly Asp Leu Met Arg Ser Val
                 920                 925                 930

 Leu Leu Leu Ala Tyr Lys Pro Met Glu Gly Asn Phe Glu Glu Ile
                 935                 940                 945

 Ala Arg Asp Phe Asn Pro Asn Trp Met Ser Ala Val Glu Ile Leu
                 950                 955                 960

 Asp Asp Asp Asn Phe Leu Gly Ala Glu Asn Ala Phe Asn Leu Phe
                 965                 970                 975

 Val Cys Gln Lys Asp Ser Ala Ala Thr Thr Asp Glu Glu Arg Gln
                 980                 985                 990

 His Leu Gln Glu Val Gly Leu Phe His Leu Gly Glu Phe Val Asn
                 995                1000                1005

 Val Phe Cys His Gly Ser Leu Val Met Gln Asn Leu Gly Glu Thr
                1010                1015                1020

 Ser Thr Pro Thr Gln Gly Ser Val Leu Phe Gly Thr Val Asn Gly
                1025                1030                1035

 Met Ile Gly Leu Val Thr Ser Leu Ser Glu Ser Trp Tyr Asn Leu
                1040                1045                1050

 Leu Leu Asp Met Gln Asn Arg Leu Asn Lys Val Ile Lys Ser Val
                1055                1060                1065

 Gly Lys Ile Glu His Ser Phe Trp Arg Ser Phe His Thr Glu Arg
                1070                1075                1080

 Lys Thr Glu Pro Ala Thr Gly Phe Ile Asp Gly Asp Leu Ile Glu
                1085                1090                1095

 Ser Phe Leu Asp Ile Ser Arg Pro Lys Met Gln Glu Val Val Ala
                1100                1105                1110

 Asn Leu Gln Tyr Asp Asp Gly Ser Gly Met Lys Arg Glu Ala Thr
                1115                1120                1125

 Ala Asp Asp Leu Ile Lys Val Val Glu Glu Leu Thr Arg Ile His
                1130                1135                1140

<210> 6114
<211> 1922
<212> DNA
<213> Homo sapien

<400> 6114
 gcccctttct ttctcctcgt cggcccgaga gcaggaacac gataacgaag 50

 gaggcccaac ttcattcaat aaggagcctg acggatttat cccagacggt 100

 agaacaaaag gaagaatatt gatggatttt aaaccagagt ttttaaagag 150

 cttgagaata cggggaaatt aatttgttct cctacacaca tagatagggt 200

 aaggttgttt ctgatgcagc tgagaaaaat gcagaccgtc aaaaaggagc 250

 aggcgtctct tgatgccagt agcaatgtgg acaagatgat ggtccttaat 300

 tctgctttaa cggaagtgtc agaagactcc acaacaggtg aggacgtgct 350

 tctcagtgaa ggaagtgtgg ggaagaacaa atcttctgca tgtcggagga 400

 aacgggaatt cattcctgat gaaaagaaag atgctatgta ttgggaaaaa 450

 aggcggaaaa ataatgaagc tgccaaaaga tctcgtgaga agcgtcgact 500

 gaatgacctg gttttagaga acaaactaat tgcactggga gaagaaaacg 550

 ccactttaaa agctgagctg ctttcactaa aattaaagtt tggtttaatt 600

 agctccacag catatgctca agagattcag aaactcagta attctacagc 650

 tgtgtacttt caagattacc agacttccaa atccaatgtg agttcatttg 700

 tggacgagca cgaaccctcg atggtgtcaa gtagttgtat ttctgtcatt 750

 aaacactctc cacaaagctc gctgtccgat gtttcagaag tgtcctcagt 800

 agaacacacg caggagagct ctgtgcaggg aagctgcaga agtcctgaaa 850

 acaagttcca gattatcaag caagagccga tggaattaga gagctacaca 900

 agggagccaa gagatgaccg aggctcttac acagcgtcca tctatcaaaa 950

 ctatatgggg aattctttct ctgggtactc acactctccc ccactactgc 1000

 aagtcaaccg atcctccagc aactccccgg gaacgtcgga aactgatgat 1050

 ggtgtggtag gaaagtcatc tgatggagaa gacgagcaac aggtccccaa 1100

 gggccccatc cattctccag ttgaactcaa gcatgtgcat gcaactgtgg 1150

 ttaaagttcc agaagtgaat tcctctgcct tgccacacaa gctccggatc 1200

 aaagccaaag ccatgcagat caaagtagaa gcctttgata atgaatttga 1250

 ggccacgcaa aaactttcct cacctattga catgacatct aaaagacatt 1300

 tcgaactcga aaagcatagt gccccaagta tggtacattc ttctcttact 1350

 cctttctcag tgcaagtgac taacattcaa gattggtctc tcaaatcgga 1400

 gcactggcat caaaaagaac tgagtggcaa aactcagaat agtttcaaaa 1450

 ctggagttgt tgaaatgaaa gacagtggct acaaagtttc tgacccagag 1500

 aacttgtatt tgaagcaggg gatagcaaac ttatctgcag aggttgtctc 1550

 actcaagaga cttatagcca cacaaccaat ctctgcttca gactctgggt 1600

 aaattactac tgagtaagag ctgggcattt agaaagatgt catttgcaat 1650

 agagcagtcc attttgtatt atgctgaatt ttcactggac ctgtgatgtc 1700

 atttcactgt gatgtgcaca tgttgtctgt ttggtgtctt tttgtgcaca 1750

 gattatgatg aagattagat tgtgttatca ctctgcctgt gtatagtcag 1800

 atagtccatg cgaaggctgt atatattgaa cattattttt gttgttctat 1850

 tataaagtgt gtaagttacc agtttcaata aaggattggt gacaaacaca 1900

 gaaaaaaaaa aaaaaaaaaa aa 1922

<210> 6115
<211> 462
<212> PRT
<213> Homo sapien

<400> 6115
 Met Gln Leu Arg Lys Met Gln Thr Val Lys Lys Glu Gln Ala Ser
   1               5                  10                  15

 Leu Asp Ala Ser Ser Asn Val Asp Lys Met Met Val Leu Asn Ser
                  20                  25                  30

 Ala Leu Thr Glu Val Ser Glu Asp Ser Thr Thr Gly Glu Asp Val
                  35                  40                  45

 Leu Leu Ser Glu Gly Ser Val Gly Lys Asn Lys Ser Ser Ala Cys
                  50                  55                  60

 Arg Arg Lys Arg Glu Phe Ile Pro Asp Glu Lys Lys Asp Ala Met
                  65                  70                  75

 Tyr Trp Glu Lys Arg Arg Lys Asn Asn Glu Ala Ala Lys Arg Ser
                  80                  85                  90

 Arg Glu Lys Arg Arg Leu Asn Asp Leu Val Leu Glu Asn Lys Leu
                  95                 100                 105

 Ile Ala Leu Gly Glu Glu Asn Ala Thr Leu Lys Ala Glu Leu Leu
                 110                 115                 120

 Ser Leu Lys Leu Lys Phe Gly Leu Ile Ser Ser Thr Ala Tyr Ala
                 125                 130                 135

 Gln Glu Ile Gln Lys Leu Ser Asn Ser Thr Ala Val Tyr Phe Gln
                 140                 145                 150

 Asp Tyr Gln Thr Ser Lys Ser Asn Val Ser Ser Phe Val Asp Glu
                 155                 160                 165

 His Glu Pro Ser Met Val Ser Ser Ser Cys Ile Ser Val Ile Lys
                 170                 175                 180

 His Ser Pro Gln Ser Ser Leu Ser Asp Val Ser Glu Val Ser Ser
                 185                 190                 195

 Val Glu His Thr Gln Glu Ser Ser Val Gln Gly Ser Cys Arg Ser
                 200                 205                 210

 Pro Glu Asn Lys Phe Gln Ile Ile Lys Gln Glu Pro Met Glu Leu
                 215                 220                 225

 Glu Ser Tyr Thr Arg Glu Pro Arg Asp Asp Arg Gly Ser Tyr Thr
                 230                 235                 240

 Ala Ser Ile Tyr Gln Asn Tyr Met Gly Asn Ser Phe Ser Gly Tyr
                 245                 250                 255

 Ser His Ser Pro Pro Leu Leu Gln Val Asn Arg Ser Ser Ser Asn
                 260                 265                 270

 Ser Pro Gly Thr Ser Glu Thr Asp Asp Gly Val Val Gly Lys Ser
                 275                 280                 285

 Ser Asp Gly Glu Asp Glu Gln Gln Val Pro Lys Gly Pro Ile His
                 290                 295                 300

 Ser Pro Val Glu Leu Lys His Val His Ala Thr Val Val Lys Val
                 305                 310                 315

 Pro Glu Val Asn Ser Ser Ala Leu Pro His Lys Leu Arg Ile Lys
                 320                 325                 330

 Ala Lys Ala Met Gln Ile Lys Val Glu Ala Phe Asp Asn Glu Phe
                 335                 340                 345

 Glu Ala Thr Gln Lys Leu Ser Ser Pro Ile Asp Met Thr Ser Lys
                 350                 355                 360

 Arg His Phe Glu Leu Glu Lys His Ser Ala Pro Ser Met Val His
                 365                 370                 375

 Ser Ser Leu Thr Pro Phe Ser Val Gln Val Thr Asn Ile Gln Asp
                 380                 385                 390

 Trp Ser Leu Lys Ser Glu His Trp His Gln Lys Glu Leu Ser Gly
                 395                 400                 405

 Lys Thr Gln Asn Ser Phe Lys Thr Gly Val Val Glu Met Lys Asp
                 410                 415                 420

 Ser Gly Tyr Lys Val Ser Asp Pro Glu Asn Leu Tyr Leu Lys Gln
                 425                 430                 435

 Gly Ile Ala Asn Leu Ser Ala Glu Val Val Ser Leu Lys Arg Leu
                 440                 445                 450

 Ile Ala Thr Gln Pro Ile Ser Ala Ser Asp Ser Gly
                 455                 460

<210> 6116
<211> 7228
<212> DNA
<213> Homo sapien

<400> 6116
 cacgcggcca ccgagctgga ggaagcggcg ggcgtgagac cgggaatgct 50

 tgggcccccg ccttcctcgc agccatccag cactcggtgc acgccccgcg 100

 aggccagcgg ctgctccctc ccggggctat tgctgctagt gccgtgagca 150

 ccgcccagcc attgtctctg tgtctccgtc agccgtgccg agccgcgcac 200

 ccagaggcga gggcgcgcat ggggagcctc cgttgatgct gccgcggctg 250

 ccgcgccgcc ctccgaggct gcgtcccggg gagtccggct tcccgagcgc 300

 tccggcctgg cccggcgccc cggacctgag tgcctcccca tggaggcgcc 350

 cgggccggcc caggcggccg cggcggagag caactcccga gaggtgacgg 400

 aggatgccgc cgactgggcg cccgcgctct gccccagccc cgaggcgcgg 450

 tcgccggagg cgcctgccta ccgcctgcag gactgcgacg cgctggtcac 500

 catgggcact gggacgttcg ggcgggtgca cctggtgaag gagaagacag 550

 ccaagcattt cttcgccctc aaggtgatga gcattcccga cgtcatccgc 600

 cggaagcagg agcagcacgt gcacaatgag aagtctgtcc tgaaggaagt 650

 cagccacccg ttcctcatca ggctgttctg gacgtggcat gaggagcgct 700

 tcctctacat gctcatggag tatgtgccgg gtggcgagct cttcagctac 750

 ctgcgcaacc gggggcactt ctccagcacc acggggctct tctactctgc 800

 ggagatcatc tgtgccattg agtacctgca ctccaaggag atcgtctaca 850

 gggatttgaa gccggagaac atcctgctgg atagggatgg tcacatcaag 900

 ctcacggact ttgggtttgc caagaagctg gtagacagga cttggaccct 950

 ctgtggaaca cccgagtacc tagcccccga agtcattcag agcaagggcc 1000

 acggaagggc cgtggactgg tgggccctcg gcatcctgat attcgagatg 1050

 ctttcggggt ttcctccatt ttttgatgac aacccgtttg gcatttatca 1100

 gaaaattctt gcaggcaaac tatatttccc cagacatttg gatttccatg 1150

 taaaaacggg gcgaatgatg tgaaccacca tcggtggttc cgctccgtgg 1200

 actggaaagc tgttccgcag agaaaactga agcctcccat cgtgcccacg 1250

 atagctggca acggcgacac ttccaacttc gaaacttacc ctgagcatga 1300

 ctgggacaca gccgcgcccg tgccgcagaa ggatttagaa atcttcaaga 1350

 atttctgagg acgagctcac atctggaaga aacaggaaga ttggaatctg 1400

 cctggaacaa agaactgcac ctaagcagac cagaagcaaa atgtcttctt 1450

 cacggcctga ggacatttcc agttttctct gtacctgtgt gtatagaaat 1500

 agatcagagc acagttgaaa ttcatggaac tggcattatt taagcaacca 1550

 gaattccaca ctgtaggaag gttttgaaaa ttgtttcgtt atagatttta 1600

 tcttatcttt tggtgttgtc ttggtttttc tcatagactt tataagtttg 1650

 aactggactt atttgattat aaccacaaat tgtgtgtgtg tgtgtgtgtg 1700

 tatatataga agtcattatg gcagatgcac aaattgtgca gtgatgtaaa 1750

 tatacatact tcacagagcc tattattttt atttttcaat tcagtttctc 1800

 aaattatctt cccttctctt ggggacaaca tctgaagggt atgttgcatg 1850

 catttttaaa aaaatcatct catatgcatt gtatagtttg ggggaataag 1900

 atatccgggg gccgggggtg tctacattca gtatctttag ttcttcctac 1950

 ctagtaactt grgactttaa aagargaaac atggagaaga tgtgggagcg 2000

 aatttattgc aggaatccac aatgactttg aagttgttgg agcaatgcat 2050

 tgtattcaga aaacctgtgt cacattaaaa aatttcatct aggctaggtg 2100

 cagtggcttg ttcctgtagt cccagcactc tgggaacctg ggttgggagg 2150

 attgcttaag gccaggagtt tgagaccagc ttgggcaaca tagtgaaccc 2200

 tgtctgtatg gaatttacac aaattataaa aattagtcgg gtgtcattgt 2250

 gcatacctgt agtcccagct attcaggagc tgttgtagga gagattgcct 2300

 gagctcaaga ggttgaggct gcagtgagcc ctgattgtgc cagtgcactc 2350

 caggctggac gacagagcaa gaccctgtat taaaaaaaaa attcatcctg 2400

 cacagggaaa tggctaccta ttaaagtccc agttgaaatt ttttgaaaaa 2450

 atacacctcc cacagttcac aaataacttt taagatcagc tcatctataa 2500

 ggctgacctt catgcagaga ttttatttca cctttagttt tgggaaaagc 2550

 gagaaacaga tgatctatag gatgtgagtg ggtggcagag tcaaaaggaa 2600

 cctcacctgt tcctaatttc tccttttaaa tattcatgtt gagtgtgcct 2650

 aatactctcc tcgacaagtc atgctgtttt atgcagaata atccaggcgt 2700

 gagagtgttc tcttgggaaa tgactgggga gacacctgaa aggagcaacc 2750

 cccagatgtt cttccctggg tgttgatggc atgacagcca tacagtgagt 2800

 ttgttctgaa acatctcttg ctaaatgtgg gtcatgctag acacagcata 2850

 aactgagggt gtggggtctg gctttgtaca taactcattt tctcccttgc 2900

 tttttctctg gaccatcctg gctggaaact tggctgtaga catctgaaga 2950

 gggtgcacct tttctcttta ctgtgactca cctcaaatat ggcattgctc 3000

 aaatctgctg tgtatgaggt cacagggccc agctgtggca ggggtgagtg 3050

 cattgaagaa gtaggttttg gagccttcca ggaattcctt gttgacaaca 3100

 ggggtacact cacacagacc tccaagactt tcttctccac ctcttctttt 3150

 tctcatgccc tgccttcatc tgtctccttc tgcacccaga gtaggggtgg 3200

 agtataccct tgccatgtgt tagtgaaaat gtgtgcagtg agaagccagt 3250

 tgggtcccct cggctcctaa tctcttctca aaactcagta gctcaggttc 3300

 tctggagcca tccggtgcat tccttgctat tggagctgtt tttccaagca 3350

 atatctggga agagatttct ccctctagca cttgctacct ctcttctgca 3400

 cacatatcac acatcagtac tgtggagagt ttctgttagg aaaagccata 3450

 catttttaaa aatgtaggca aaatgtcaag ggaaatgtaa tcagatttgg 3500

 gccagagttc gcctacagat aagaaggcac tggggccagg ctcacacctg 3550

 taatcctaag taacactttg ggaggctggg gcgagaggat tgcttgagcc 3600

 caggagttca atacctgtct gggaaacacc tcatctctac aaaatacaaa 3650

 aaagttaact gggcatggtg gagcatgcct gtagtctcag ctactcagga 3700

 ggctgagatg agaggatcac ttgagcctga ggaggtccag gccacagtga 3750

 tctgagatca caccattgcc ctccagcctg ggtgacagag tgagaccctg 3800

 ttccaaaaaa aaaaaaaaac ccaaaaaacc tcaatggctt tttgcttttg 3850

 aaggtggtat gaagagaacg tccactttaa ggctttaaaa gacagtgaag 3900

 ctggttgtag ggctcacttt tataatccta ggatttgggg aagctgaagc 3950

 agaaagattg cttgagcctg ggagtttgag actggcctgg gcagcatagc 4000

 gagaccccat ctctatataa aaaaaaagat gttaaaacag tgaaattaca 4050

 gaaacagaac atagccaccc tgtttcatca gtgacctttt cttcacgtga 4100

 cggtcaactc agtaggtgag aataattagt aggttcagca gaataaactc 4150

 tttacaatta ataactcagt ggaaaatgat gttcagatgg tgaaatgtgg 4200

 aaatgtttta gacaactcta ttttcagcct gtgcttctca ctcaccatcc 4250

 tgttgggatt aacagttgag ggccatcgct gcctaaacat ttagcgtgcg 4300

 gtttcccatc agttttactg tgaatgtgaa aaggtgaaac tgttgctgac 4350

 ttcggtagca ggtatactaa aattggaatg acacagagga gattagcatg 4400

 gccccctgcg cgaggaagat ccgcagattc atgcagcatt ccatattttt 4450

 ttaaaaaaag gttacactgt gcaccgacgt ggagctagaa ggaaaagcat 4500

 gaagtctcat gtttgctgac tataaaaata aatcatagta ataatattat 4550

 tgaacattct actttaaaaa ttattaataa aaccataaat gaaacacttg 4600

 agcacacttt aaaaagtaca taaacccatg agtccatatg tgtaatttta 4650

 tgttgtctgt tttattatcc aggatttcat actcagatga gcattagcat 4700

 caggaaagcc tgaaatgcct taattgtgaa ctgatacgca ggaaaatgaa 4750

 atatgtaagc acattggtga ccttgttctt tacagacatc atgatcagcc 4800

 tccagccata cagaacaaat gagaaattag aagcaattcc aagaacgtgt 4850

 gatggtgtga acccactttt gaccgtcaca cacatttcag catttgaaga 4900

 gacacaggct acctggaaac tgcccatggc ggggtcataa tttaaatgtc 4950

 ccaatgtcat atagaggtta atttaatcaa aatgagctaa aacatggaac 5000

 aatcactgaa taatttaaaa agagtttacc tggcagagtg tgtcatgcct 5050

 gcaatcccag cactttggga ggccaaggca ggcagatcac ctgaggtcag 5100

 gagtttgaga ccagcctggc caacatgatg aaacccttgt ctctattaaa 5150

 aacacaaaaa ttagccagat gtggtggcac atgcctgtaa tcccagttag 5200

 tcgggaggct gaggcaggag aatatggaac tcaggaggcg gaggctgcag 5250

 tcaaccaaga ttgcgccact gcactccagc cagggcgaag gagtgagact 5300

 cccatctcaa aaaataaaaa aaaaaataaa taaaaatagt tgacccgggt 5350

 gggcattcca aaatgttccc atagatgatc gtgaaacaat cactgtgcaa 5400

 aatgtagagg aaaattctta cgataatcac aaaatttgta tcagaaaaac 5450

 attacaaatt tactttgctc catgtaattt tatgaattgg cagtattttc 5500

 ttaaattggg atacagtaag agaatatctt taggaaatgg aaatgttaaa 5550

 acaagaagta acaagaggtt gtttttctga agggaaatgc caccggcctg 5600

 ctttcatagg cattgataaa gccaggaagg aaataaagtc acaaccgaat 5650

 agtatacact gtatctactg aattcttcta attccttcac aacagaagtc 5700

 taaatcctgc ttagcctaaa catatctata gccagcgatg ggcaaattat 5750

 atttgctgtc agcatgatgg aataagaaac agaaaccccc cagcagtggg 5800

 taagattgca cgcttcatcc cctcaaaatg cagttcagcc ccactccctc 5850

 tccatgccca tcaaacaact gcaaaatcac ttgttactga atttctcatt 5900

 cagcgttttg tttcttttct gtccatattc aagacctttt tatttgtttg 5950

 ctttgaagaa aaagcaaaag caacaaaaca ccaaatcatt tgaaattcca 6000

 accttaaccc cccaatttta aaaaaaaatt ccaccagtgg aactaaacag 6050

 ttgagtggtt tgggatgtgt tgttcgccat ttctgtgttt gacctacatg 6100

 gtctctagtt ctttggacaa ttgtaactgt gaaactatgg cttaacactg 6150

 ttaaagactc caaggctcca ctctgtagcc aggtgcaact caggctgcac 6200

 aaatacccca ccagaatgtc acaatcattc attgctccag ctgctgagtg 6250

 aacagagtgc aagacagcac tggcttgggt tttatttttg cagccagtta 6300

 actttgcatc aggtctacac agtccttgca gcctttgatt tctccagttg 6350

 tacagatttg aaatggggtg cccgggttcc tctcgttttt ccttcaatct 6400

 acctagcatg cattttacac acattggagg agtcgatgca ctgtttttct 6450

 cttgctgatg gaggcaagaa cgccttctaa ttagtataac ttaaatggac 6500

 gggattgact taaaagcaag aagaaaagca catgaacagg tgtcttaatg 6550

 catttggata ctttggggtg tgtgcctgtc tgtgtgtgtg tcttggtgaa 6600

 ggtgggctgt attttcacca agccttttca taatcaagtt tgctttgcaa 6650

 accatctgcc ttgcccccag cagtacagtc cttcctaata acggggatgc 6700

 tctgtcatgt ttctctgtaa attgttgtgt gttgggaagt tctgttgagg 6750

 cttagtttga tcttccatgg tggacatgtc tgttctgtat ataaaaagca 6800

 ttacatctgt gttttagcag gtgggatttg aagcttttcc acagtccttg 6850

 tgctctgaga tggctgttga gctctgctca gctgtcacag ctgaattctt 6900

 tttttgtgct gaacactggg cagcctcgcc ttgttgccaa cgtgcttctg 6950

 gggcccctgt gactgctgcc ggatgctgtg cacacaggca gagtgccttg 7000

 gcaggtttgt gcaccccttg gcgagccaga actgggaacc ccgcggagtg 7050

 accccacctt ctcatggggg gtcagggagg ggagtgccta tttttaatct 7100

 tgtttgttgc gcaatggaaa tcactgtgat ttgtacatat gccctaggaa 7150

 aattttaccg ctgtctaatt tatgtaataa tactgatgat tctaggtttg 7200

 cccaataaac tttatatctt ttcagaag 7228

<210> 6117
<211> 277
<212> PRT
<213> Homo sapien

<400> 6117
 Met Glu Ala Pro Gly Pro Ala Gln Ala Ala Ala Ala Glu Ser Asn
   1               5                  10                  15

 Ser Arg Glu Val Thr Glu Asp Ala Ala Asp Trp Ala Pro Ala Leu
                  20                  25                  30

 Cys Pro Ser Pro Glu Ala Arg Ser Pro Glu Ala Pro Ala Tyr Arg
                  35                  40                  45

 Leu Gln Asp Cys Asp Ala Leu Val Thr Met Gly Thr Gly Thr Phe
                  50                  55                  60

 Gly Arg Val His Leu Val Lys Glu Lys Thr Ala Lys His Phe Phe
                  65                  70                  75

 Ala Leu Lys Val Met Ser Ile Pro Asp Val Ile Arg Arg Lys Gln
                  80                  85                  90

 Glu Gln His Val His Asn Glu Lys Ser Val Leu Lys Glu Val Ser
                  95                 100                 105

 His Pro Phe Leu Ile Arg Leu Phe Trp Thr Trp His Glu Glu Arg
                 110                 115                 120

 Phe Leu Tyr Met Leu Met Glu Tyr Val Pro Gly Gly Glu Leu Phe
                 125                 130                 135

 Ser Tyr Leu Arg Asn Arg Gly His Phe Ser Ser Thr Thr Gly Leu
                 140                 145                 150

 Phe Tyr Ser Ala Glu Ile Ile Cys Ala Ile Glu Tyr Leu His Ser
                 155                 160                 165

 Lys Glu Ile Val Tyr Arg Asp Leu Lys Pro Glu Asn Ile Leu Leu
                 170                 175                 180

 Asp Arg Asp Gly His Ile Lys Leu Thr Asp Phe Gly Phe Ala Lys
                 185                 190                 195

 Lys Leu Val Asp Arg Thr Trp Thr Leu Cys Gly Thr Pro Glu Tyr
                 200                 205                 210

 Leu Ala Pro Glu Val Ile Gln Ser Lys Gly His Gly Arg Ala Val
                 215                 220                 225

 Asp Trp Trp Ala Leu Gly Ile Leu Ile Phe Glu Met Leu Ser Gly
                 230                 235                 240

 Phe Pro Pro Phe Phe Asp Asp Asn Pro Phe Gly Ile Tyr Gln Lys
                 245                 250                 255

 Ile Leu Ala Gly Lys Leu Tyr Phe Pro Arg His Leu Asp Phe His
                 260                 265                 270

 Val Lys Thr Gly Arg Met Met
                 275

<210> 6118
<211> 1686
<212> DNA
<213> Homo sapien

<400> 6118
 ccacgcgtcc gggcgtaagc caggcgtgtt aaagccggtc ggaactgctc 50

 cggagggcac gggctccgta ggcaccaact gcaaggaccc ctccccctgc 100

 gggcgctccc atggcacagt tcgcgttcga gagtgacctg cactcgctgc 150

 ttcagctgga tgcacccatc cccaatgcac cccctgcgcg ctggcagcgc 200

 aaagccaagg aagccgcagg cccggccccc tcacccatgc gggccgccaa 250

 ccgatcccac agcgccggca ggactccggg ccgaactcct ggcaaatcca 300

 gttccaaggt tcagaccact cctagcaaac ctggcggtga ccgctatatc 350

 ccccatcgca gtgctgccca gatggaggtg gccagcttcc tcctgagcaa 400

 ggagaaccag tctgaaaaca gccagacgcc caccaagaag gaacatcaga 450

 aagcctgggc tttgaacctg aacggttttg atgtagagga agccaagatc 500

 cttcggctca gtggaaaacc acaaaatgcg ccagagggtt atcagaacag 550

 actgaaagta ctctacagcc aaaaggccac tcctggctcc agccggaaga 600

 cctgccgtta cattccttcc ctgccagacc gtatcctgga tgcgcctgaa 650

 atccgaaatg actattacct gaaccttgtg gattggagtt ctgggaatgt 700

 actggccgtg gcactggaca acagtgtgta cctgtggagt gcaagctctg 750

 gtgacatcct gcagcttttg caaatggagc agcctgggga atatatatcc 800

 tctgtggcct ggatcaaaga gggcaactac ttggctgtgg gcaccagcag 850

 tgctgaggtg cagctatggg atgtgcagca gcagaaacgg cttcgaaata 900

 tgaccagtca ctctgcccga gtgggctccc taagctggaa cagctatatc 950

 ctgtccagtg gttcacgttc tggccacatc caccaccatg atgttcgggt 1000

 agcagaacac catgtggcca cactgagtgg ccacagccag gaagtgtgtg 1050

 ggctgcgctg ggccccagat ggacgacatt tggccagtgg tggtaatgat 1100

 aacttggtca atgtgtggcc tagtgctcct ggagagggtg gctgggttcc 1150

 tctgcagaca ttcacccagc atcaaggggc tgtcaaggcc gtagcatggt 1200

 gtccctggca gtccaatgtc ctggcaacag gagggggcac cagtgatcga 1250

 cacattcgca tctggaatgt gtgctctggg gcctgtctga gtgccgtgga 1300

 tgcccattcc caggtgtgct ccatcctctg gtctccccat tacaaggagc 1350

 tcatctcagg ccatggcttt gcacagaacc agctagttat ttggaagtac 1400

 ccaaccatgg ccaaggtggc tgaactcaaa ggtcacacat cccgggtcct 1450

 gagtctgacc atgagcccag atggggccac agtggcatcc gcagcagcag 1500

 atgagaccct gaggctatgg cgctgttttg agttggaccc tgcgcggcgg 1550

 cgggagcggg agaaggccag tgcagccaaa agcagcctca tccaccaagg 1600

 catccgctga agaccaaccc atcacctcag ttgtttttta tttttctaat 1650

 aaagtcatgt ctcccttcat gttttttttt ttaaaa 1686

<210> 6119
<211> 499
<212> PRT
<213> Homo sapien

<400> 6119
 Met Ala Gln Phe Ala Phe Glu Ser Asp Leu His Ser Leu Leu Gln
   1               5                  10                  15

 Leu Asp Ala Pro Ile Pro Asn Ala Pro Pro Ala Arg Trp Gln Arg
                  20                  25                  30

 Lys Ala Lys Glu Ala Ala Gly Pro Ala Pro Ser Pro Met Arg Ala
                  35                  40                  45

 Ala Asn Arg Ser His Ser Ala Gly Arg Thr Pro Gly Arg Thr Pro
                  50                  55                  60

 Gly Lys Ser Ser Ser Lys Val Gln Thr Thr Pro Ser Lys Pro Gly
                  65                  70                  75

 Gly Asp Arg Tyr Ile Pro His Arg Ser Ala Ala Gln Met Glu Val
                  80                  85                  90

 Ala Ser Phe Leu Leu Ser Lys Glu Asn Gln Ser Glu Asn Ser Gln
                  95                 100                 105

 Thr Pro Thr Lys Lys Glu His Gln Lys Ala Trp Ala Leu Asn Leu
                 110                 115                 120

 Asn Gly Phe Asp Val Glu Glu Ala Lys Ile Leu Arg Leu Ser Gly
                 125                 130                 135

 Lys Pro Gln Asn Ala Pro Glu Gly Tyr Gln Asn Arg Leu Lys Val
                 140                 145                 150

 Leu Tyr Ser Gln Lys Ala Thr Pro Gly Ser Ser Arg Lys Thr Cys
                 155                 160                 165

 Arg Tyr Ile Pro Ser Leu Pro Asp Arg Ile Leu Asp Ala Pro Glu
                 170                 175                 180

 Ile Arg Asn Asp Tyr Tyr Leu Asn Leu Val Asp Trp Ser Ser Gly
                 185                 190                 195

 Asn Val Leu Ala Val Ala Leu Asp Asn Ser Val Tyr Leu Trp Ser
                 200                 205                 210

 Ala Ser Ser Gly Asp Ile Leu Gln Leu Leu Gln Met Glu Gln Pro
                 215                 220                 225

 Gly Glu Tyr Ile Ser Ser Val Ala Trp Ile Lys Glu Gly Asn Tyr
                 230                 235                 240

 Leu Ala Val Gly Thr Ser Ser Ala Glu Val Gln Leu Trp Asp Val
                 245                 250                 255

 Gln Gln Gln Lys Arg Leu Arg Asn Met Thr Ser His Ser Ala Arg
                 260                 265                 270

 Val Gly Ser Leu Ser Trp Asn Ser Tyr Ile Leu Ser Ser Gly Ser
                 275                 280                 285

 Arg Ser Gly His Ile His His His Asp Val Arg Val Ala Glu His
                 290                 295                 300

 His Val Ala Thr Leu Ser Gly His Ser Gln Glu Val Cys Gly Leu
                 305                 310                 315

 Arg Trp Ala Pro Asp Gly Arg His Leu Ala Ser Gly Gly Asn Asp
                 320                 325                 330

 Asn Leu Val Asn Val Trp Pro Ser Ala Pro Gly Glu Gly Gly Trp
                 335                 340                 345

 Val Pro Leu Gln Thr Phe Thr Gln His Gln Gly Ala Val Lys Ala
                 350                 355                 360

 Val Ala Trp Cys Pro Trp Gln Ser Asn Val Leu Ala Thr Gly Gly
                 365                 370                 375

 Gly Thr Ser Asp Arg His Ile Arg Ile Trp Asn Val Cys Ser Gly
                 380                 385                 390

 Ala Cys Leu Ser Ala Val Asp Ala His Ser Gln Val Cys Ser Ile
                 395                 400                 405

 Leu Trp Ser Pro His Tyr Lys Glu Leu Ile Ser Gly His Gly Phe
                 410                 415                 420

 Ala Gln Asn Gln Leu Val Ile Trp Lys Tyr Pro Thr Met Ala Lys
                 425                 430                 435

 Val Ala Glu Leu Lys Gly His Thr Ser Arg Val Leu Ser Leu Thr
                 440                 445                 450

 Met Ser Pro Asp Gly Ala Thr Val Ala Ser Ala Ala Ala Asp Glu
                 455                 460                 465

 Thr Leu Arg Leu Trp Arg Cys Phe Glu Leu Asp Pro Ala Arg Arg
                 470                 475                 480

 Arg Glu Arg Glu Lys Ala Ser Ala Ala Lys Ser Ser Leu Ile His
                 485                 490                 495

 Gln Gly Ile Arg


<210> 6120
<211> 3026
<212> DNA
<213> Homo sapien

<400> 6120
 ggagcagttc cgccgggttt cactgtccgt gacttccttc ggggcacctc 50

 aggcagcaaa ccaagatgga gtatgagtgg aaacctgacg agcaagggct 100

 tcagcaaatc ctgcagctgt tgaaggagtc ccagtcccca gacaccacca 150

 tccagagaac cgtgcaacaa aaactggaac aacttaatca gtatccagac 200

 tttaacaact acttgatttt tgttcttaca aaattaaaat ctgaagatga 250

 acccacaaga tcattgagtg gtcttatctt gaagaataat gtgaaagcac 300

 actttcagaa cttcccaaat ggtgtaacag actttattaa aagtgaatgt 350

 ttaaataata ttggtgactc ctctcctctg attagagcca ctgttggtat 400

 tttgatcaca actatagcct ccaagggaga attgcagaat tggcctgacc 450

 tcttaccaaa actctgtagc ctgttggatt ctgaagatta taatacctgt 500

 gagggagcat ttggtgccct tcagaagatt tgtgaagatt ctgctgagat 550

 tttagacagt gatgttttag atcgtcctct caacatcatg attcccaaat 600

 ttttacagtt cttcaagcat agtagtccaa aaataaggtc tcacgctgtt 650

 gcatgtgtca atcagtttat catcagtagg actcaagctc taatgttgca 700

 cattgattct tttattgaga atctctttgc attagctggt gatgaagaac 750

 cagaggtacg gaaaaatgtg tgccgagcac ttgtgatgtt gctcgaagtt 800

 cgaatggatc gcctgcttcc tcacatgcat aatatagttg agtacatgct 850

 acagaggact caagatcaag atgaaaatgt ggctttagaa gcctgtgaat 900

 tttggctaac tttagctgaa cagccaatat gcaaagatgt actcgtaagg 950

 catcttccta agttgattcc tgtgttagtg aatggcatga agtactcaga 1000

 catagatatt atcctactta agggtgatgt tgaagaagac gaaacgattc 1050

 ctgatagtga acaggatata cggccacgtt ttcaccgatc gaggacggtg 1100

 gctcagcagc atgatgaaga tggaattgaa gaggaagatg atgatgatga 1150

 tgaaattgat gatgatgata caatttctga ctggaatcta agaaaatgtt 1200

 ctgctgctgc cctggatgtt cttgcaaatg tgtatcgtga tgaactgctg 1250

 ccacatattt tgcccctttt gaaagaatta ctttttcatc atgaatgggt 1300

 tgttaaagaa tcaggcattt tggttttagg agcaattgct gaaggttgca 1350

 tgcagggcat gattccatac ttgcctgagc ttattcctca ccttattcag 1400

 tgcctctctg ataaaaaggc tcttgtgcgt tccataacat gctggactct 1450

 tagccgctat gcacactggg tggtcagcca gccgccagac acgtacctga 1500

 agccattaat gacagaattg ctaaagcgca tcctggacag caacaagaga 1550

 gtacaagaag ctgcctgcag tgcctttgct accctagaag aggaggcttg 1600

 tacagaactt gttccttacc ttgcttatat acttgatacc ctggtctttg 1650

 catttagtaa ataccagcat aagaacctgc tcattcttta cgatgccata 1700

 ggaacattag cagattcagt aggacatcat ttaaacaaac cagaatatat 1750

 tcagatgcta atgcctccac tgatccagaa atggaacatg ttaaaggatg 1800

 aagataaaga tctcttccct ttacttgagt gcctatcttc agttgccaca 1850

 gcactgcagt ctggattcct tccgtactgt gaacctgtgt atcagcgttg 1900

 tgtaaaccta gtacagaaga ctcttgcaca agccatgcta aacaatgctc 1950

 aaccagatca atatgaagct ccagataaag attttatgat agtggctctt 2000

 gatttactga gtggcctggc tgaaggactt ggaggcaaca ttgaacagct 2050

 ggtagcccga agtaacatcc tgacactaat gtatcagtgc atgcaggata 2100

 aaatgccaga agttcgacag agttcttttg ccctgttagg tgacctcaca 2150

 aaagcttgct ttcagcatgt taagccttgt atagctgatt tcatgccaat 2200

 attgggaacc aacctaaatc cagaattcat ttcagtctgc aacaatgcca 2250

 catgggcaat tggagaaatc tccattcaaa tgggtataga gatgcagcct 2300

 tatattccta tggtgttgca ccagcttgta gaaatcatta acagacccaa 2350

 cacaccaaag acgttgttag agaatacagc aataacaatt ggtcgtcttg 2400

 gttacgtttg tcctcaagag gtggccccca tgctacagca gtttataaga 2450

 ccctggtgca cctctctgag aaacataaga gacaatgagg aaaaggattc 2500

 agcattccgt ggaatttgta ccatgatcag tgtgaatccc agtggcgtaa 2550

 tccaagattt tatatttttt tgtgatgccg ttgcatcatg gattaaccca 2600

 aaagatgatc tcagagacat gttctgtaag atccttcatg gatttaaaaa 2650

 tcaagttggc gatgaaaatt ggaggcgttt ctctgaccag tttcctcttc 2700

 ccttaaaaga gcgtcttgca gctttttatg gtgtttaatc taatacactt 2750

 aagctgcagt cccaaaatta ggggtccttc agtcttggag actataaggg 2800

 agcctctgca cccagggaaa atgttaccct ttacaggggg gaagggtaaa 2850

 ccagtaggga atacagtaca atcccaaccc tactgggagg ggcgggaggg 2900

 aggtgttgcc gtcactgtat taagtcgatg ttgggaaacg ttttaacatc 2950

 tggagccttt gtgggtggaa atatgtctcc agttacaact ccgcagtgga 3000

 tgtgaagaag caaaaaaaaa aaaaaa 3026

<210> 6121
<211> 890
<212> PRT
<213> Homo sapien

<400> 6121
 Met Glu Tyr Glu Trp Lys Pro Asp Glu Gln Gly Leu Gln Gln Ile
   1               5                  10                  15

 Leu Gln Leu Leu Lys Glu Ser Gln Ser Pro Asp Thr Thr Ile Gln
                  20                  25                  30

 Arg Thr Val Gln Gln Lys Leu Glu Gln Leu Asn Gln Tyr Pro Asp
                  35                  40                  45

 Phe Asn Asn Tyr Leu Ile Phe Val Leu Thr Lys Leu Lys Ser Glu
                  50                  55                  60

 Asp Glu Pro Thr Arg Ser Leu Ser Gly Leu Ile Leu Lys Asn Asn
                  65                  70                  75

 Val Lys Ala His Phe Gln Asn Phe Pro Asn Gly Val Thr Asp Phe
                  80                  85                  90

 Ile Lys Ser Glu Cys Leu Asn Asn Ile Gly Asp Ser Ser Pro Leu
                  95                 100                 105

 Ile Arg Ala Thr Val Gly Ile Leu Ile Thr Thr Ile Ala Ser Lys
                 110                 115                 120

 Gly Glu Leu Gln Asn Trp Pro Asp Leu Leu Pro Lys Leu Cys Ser
                 125                 130                 135

 Leu Leu Asp Ser Glu Asp Tyr Asn Thr Cys Glu Gly Ala Phe Gly
                 140                 145                 150

 Ala Leu Gln Lys Ile Cys Glu Asp Ser Ala Glu Ile Leu Asp Ser
                 155                 160                 165

 Asp Val Leu Asp Arg Pro Leu Asn Ile Met Ile Pro Lys Phe Leu
                 170                 175                 180

 Gln Phe Phe Lys His Ser Ser Pro Lys Ile Arg Ser His Ala Val
                 185                 190                 195

 Ala Cys Val Asn Gln Phe Ile Ile Ser Arg Thr Gln Ala Leu Met
                 200                 205                 210

 Leu His Ile Asp Ser Phe Ile Glu Asn Leu Phe Ala Leu Ala Gly
                 215                 220                 225

 Asp Glu Glu Pro Glu Val Arg Lys Asn Val Cys Arg Ala Leu Val
                 230                 235                 240

 Met Leu Leu Glu Val Arg Met Asp Arg Leu Leu Pro His Met His
                 245                 250                 255

 Asn Ile Val Glu Tyr Met Leu Gln Arg Thr Gln Asp Gln Asp Glu
                 260                 265                 270

 Asn Val Ala Leu Glu Ala Cys Glu Phe Trp Leu Thr Leu Ala Glu
                 275                 280                 285

 Gln Pro Ile Cys Lys Asp Val Leu Val Arg His Leu Pro Lys Leu
                 290                 295                 300

 Ile Pro Val Leu Val Asn Gly Met Lys Tyr Ser Asp Ile Asp Ile
                 305                 310                 315

 Ile Leu Leu Lys Gly Asp Val Glu Glu Asp Glu Thr Ile Pro Asp
                 320                 325                 330

 Ser Glu Gln Asp Ile Arg Pro Arg Phe His Arg Ser Arg Thr Val
                 335                 340                 345

 Ala Gln Gln His Asp Glu Asp Gly Ile Glu Glu Glu Asp Asp Asp
                 350                 355                 360

 Asp Asp Glu Ile Asp Asp Asp Asp Thr Ile Ser Asp Trp Asn Leu
                 365                 370                 375

 Arg Lys Cys Ser Ala Ala Ala Leu Asp Val Leu Ala Asn Val Tyr
                 380                 385                 390

 Arg Asp Glu Leu Leu Pro His Ile Leu Pro Leu Leu Lys Glu Leu
                 395                 400                 405

 Leu Phe His His Glu Trp Val Val Lys Glu Ser Gly Ile Leu Val
                 410                 415                 420

 Leu Gly Ala Ile Ala Glu Gly Cys Met Gln Gly Met Ile Pro Tyr
                 425                 430                 435

 Leu Pro Glu Leu Ile Pro His Leu Ile Gln Cys Leu Ser Asp Lys
                 440                 445                 450

 Lys Ala Leu Val Arg Ser Ile Thr Cys Trp Thr Leu Ser Arg Tyr
                 455                 460                 465

 Ala His Trp Val Val Ser Gln Pro Pro Asp Thr Tyr Leu Lys Pro
                 470                 475                 480

 Leu Met Thr Glu Leu Leu Lys Arg Ile Leu Asp Ser Asn Lys Arg
                 485                 490                 495

 Val Gln Glu Ala Ala Cys Ser Ala Phe Ala Thr Leu Glu Glu Glu
                 500                 505                 510

 Ala Cys Thr Glu Leu Val Pro Tyr Leu Ala Tyr Ile Leu Asp Thr
                 515                 520                 525

 Leu Val Phe Ala Phe Ser Lys Tyr Gln His Lys Asn Leu Leu Ile
                 530                 535                 540

 Leu Tyr Asp Ala Ile Gly Thr Leu Ala Asp Ser Val Gly His His
                 545                 550                 555

 Leu Asn Lys Pro Glu Tyr Ile Gln Met Leu Met Pro Pro Leu Ile
                 560                 565                 570

 Gln Lys Trp Asn Met Leu Lys Asp Glu Asp Lys Asp Leu Phe Pro
                 575                 580                 585

 Leu Leu Glu Cys Leu Ser Ser Val Ala Thr Ala Leu Gln Ser Gly
                 590                 595                 600

 Phe Leu Pro Tyr Cys Glu Pro Val Tyr Gln Arg Cys Val Asn Leu
                 605                 610                 615

 Val Gln Lys Thr Leu Ala Gln Ala Met Leu Asn Asn Ala Gln Pro
                 620                 625                 630

 Asp Gln Tyr Glu Ala Pro Asp Lys Asp Phe Met Ile Val Ala Leu
                 635                 640                 645

 Asp Leu Leu Ser Gly Leu Ala Glu Gly Leu Gly Gly Asn Ile Glu
                 650                 655                 660

 Gln Leu Val Ala Arg Ser Asn Ile Leu Thr Leu Met Tyr Gln Cys
                 665                 670                 675

 Met Gln Asp Lys Met Pro Glu Val Arg Gln Ser Ser Phe Ala Leu
                 680                 685                 690

 Leu Gly Asp Leu Thr Lys Ala Cys Phe Gln His Val Lys Pro Cys
                 695                 700                 705

 Ile Ala Asp Phe Met Pro Ile Leu Gly Thr Asn Leu Asn Pro Glu
                 710                 715                 720

 Phe Ile Ser Val Cys Asn Asn Ala Thr Trp Ala Ile Gly Glu Ile
                 725                 730                 735

 Ser Ile Gln Met Gly Ile Glu Met Gln Pro Tyr Ile Pro Met Val
                 740                 745                 750

 Leu His Gln Leu Val Glu Ile Ile Asn Arg Pro Asn Thr Pro Lys
                 755                 760                 765

 Thr Leu Leu Glu Asn Thr Ala Ile Thr Ile Gly Arg Leu Gly Tyr
                 770                 775                 780

 Val Cys Pro Gln Glu Val Ala Pro Met Leu Gln Gln Phe Ile Arg
                 785                 790                 795

 Pro Trp Cys Thr Ser Leu Arg Asn Ile Arg Asp Asn Glu Glu Lys
                 800                 805                 810

 Asp Ser Ala Phe Arg Gly Ile Cys Thr Met Ile Ser Val Asn Pro
                 815                 820                 825

 Ser Gly Val Ile Gln Asp Phe Ile Phe Phe Cys Asp Ala Val Ala
                 830                 835                 840

 Ser Trp Ile Asn Pro Lys Asp Asp Leu Arg Asp Met Phe Cys Lys
                 845                 850                 855

 Ile Leu His Gly Phe Lys Asn Gln Val Gly Asp Glu Asn Trp Arg
                 860                 865                 870

 Arg Phe Ser Asp Gln Phe Pro Leu Pro Leu Lys Glu Arg Leu Ala
                 875                 880                 885

 Ala Phe Tyr Gly Val
                 890

<210> 6122
<211> 2383
<212> DNA
<213> Homo sapien

<400> 6122
 ggggctaccg cgcctttgct tcctggcgca cgcggagcct cctggagcct 50

 gccaccatcc tgcctactac gtgctgccct gcgcccgcag ccatgtgccg 100

 caccctggcc gccttcccca ccacctgcct ggagagagcc aaagagttca 150

 agacacgtct ggggatcttt cttcacaaat cagagctggg ctgcgatact 200

 gggagtactg gcaagtccga gtggggcagt aaacacagca aagagaatag 250

 aaacttctca gaagatgtgc tggggtggag agagtcgttc gacctgctgc 300

 tgagcagtaa aaatggagtg gctgccttcc acgctttcct gaagacagag 350

 ttcagtgagg agaacctgga gttctggctg gcctgtgagg agttcaagaa 400

 gatccgatca gctaccaagc tggcctccag ggcacaccag atctttgagg 450

 agttcatttg cagtgaggcc cctaaagagg tcaacattga ccatgagacc 500

 cgcgagctga cgaggatgaa cctgcagact gccacagcca catgctttga 550

 tgcggctcag gggaagacac gtaccctgat ggagaaggac tcctacccac 600

 gcttcctgaa gtcgcctgct taccgggacc tggctgccca agcctcagcc 650

 gcctctgcca ctctgtccag ctgcagcctg gacgagccct cacacacctg 700

 agtctccacg gcagtgagga agccagccgg gaagagaggt tgagtcaccc 750

 atccccgagg tggctgcccc tgtgtgggag gcaggttctg caaagcaagt 800

 gcaagaggac aaaaaaaaaa aaaaaaaaaa aaaaaatgcg ctccagcagc 850

 ctgtttggga agcagcagtc tctccttcag atactgtggg actcatgctg 900

 gagaggagcc gcccacttcc aggacctgtg aataagggct aatgatgagg 950

 gttggtgggg ctctctgtgg ggcaaaaagg tggtatgggg gttagcactg 1000

 gctctcgttc tcaccggaga aggaagtgtt ctagtgtggt ttaggaaaca 1050

 tgtggataaa gggaaccatg aaaatgagag gaggaaagac atccagatca 1100

 gctgttttgc ctgttgctca gttgactctg attgcatcct gttttcctaa 1150

 ttcccagact gttctgggca cggaagggac cctggatgtg gagtcttccc 1200

 ctttggccct cctcactggc ctctgggcta gcccagagtc ccttagcttg 1250

 tacctcgtaa cactcctgtg tgtctgtcca gccttgcagt catgtcaagg 1300

 ccagcaagct gatgtgactc ttgccccatg cgagatattt atacctcaaa 1350

 cactggcctg tgagcccttt ccaagtcagt ggagagccct gaaaggaggc 1400

 tcacttgaat ccagctcagt gctctgggtg gccccctgca ggtggcccct 1450

 gaccctgcgt tgcagcaggg tccacctgtg agcaggcccg ccctggggcc 1500

 tcttcctgga tgtgccctct ctgagttctg tgctgtctct tggaggcagg 1550

 gcccaggaga acaaagtgtg gaggcctcgg ggagtggctt ttccagctct 1600

 catgccccgc agtgtggaac aaggcagaaa aggatcctag gaaataagtc 1650

 tcttggcggt ccctgagagt cctgctgaaa tccagccagt gttttttgtg 1700

 gtatgagaac aggcaaaaag agatgccccg agatagaagg ggagccttgt 1750

 gtttctttcc tgcagacgtg agatgaacac tggagtgggc agaggtggcm 1800

 caggaccatg gcacccttag agtgcagaag ctggggggag aggctgcttc 1850

 gaagggcagg actggggata cctgcctgtc acctcagggc atcactgaac 1900

 aaacatttcc tgatggsaac tcctgcggca gagcccaggc tggggaagtg 1950

 aactacccag ggcagcccct ttgtggccca ggataatcaa cactgttctc 2000

 tctgtaccat gagctcctcc aggagattat ttaagtgtat tgtatcattg 2050

 gttttctgtg attgtcataa cattgttttt gttattgttg gtgctgttgt 2100

 tatttattat tgtaatttca gtttgcctct actggagaat ctcagcaggg 2150

 gtttcagcct gactgtctcc ctttctctac cagactctac ctctgaatgt 2200

 gctgggaacc tcttggagcc tgtcaggaac tcctcactgt ttaaatattt 2250

 atttattgtg acaaatggag ctggtttcct agatatgaat gatgtttgca 2300

 atccccattt tcctgtttca gcatgttata ttcttataaa ataaaagcaa 2350

 aagtcaaata tgaaaaaaaa aaaaaaaaaa aaa 2383

<210> 6123
<211> 202
<212> PRT
<213> Homo sapien

<400> 6123
 Met Cys Arg Thr Leu Ala Ala Phe Pro Thr Thr Cys Leu Glu Arg
   1               5                  10                  15

 Ala Lys Glu Phe Lys Thr Arg Leu Gly Ile Phe Leu His Lys Ser
                  20                  25                  30

 Glu Leu Gly Cys Asp Thr Gly Ser Thr Gly Lys Ser Glu Trp Gly
                  35                  40                  45

 Ser Lys His Ser Lys Glu Asn Arg Asn Phe Ser Glu Asp Val Leu
                  50                  55                  60

 Gly Trp Arg Glu Ser Phe Asp Leu Leu Leu Ser Ser Lys Asn Gly
                  65                  70                  75

 Val Ala Ala Phe His Ala Phe Leu Lys Thr Glu Phe Ser Glu Glu
                  80                  85                  90

 Asn Leu Glu Phe Trp Leu Ala Cys Glu Glu Phe Lys Lys Ile Arg
                  95                 100                 105

 Ser Ala Thr Lys Leu Ala Ser Arg Ala His Gln Ile Phe Glu Glu
                 110                 115                 120

 Phe Ile Cys Ser Glu Ala Pro Lys Glu Val Asn Ile Asp His Glu
                 125                 130                 135

 Thr Arg Glu Leu Thr Arg Met Asn Leu Gln Thr Ala Thr Ala Thr
                 140                 145                 150

 Cys Phe Asp Ala Ala Gln Gly Lys Thr Arg Thr Leu Met Glu Lys
                 155                 160                 165

 Asp Ser Tyr Pro Arg Phe Leu Lys Ser Pro Ala Tyr Arg Asp Leu
                 170                 175                 180

 Ala Ala Gln Ala Ser Ala Ala Ser Ala Thr Leu Ser Ser Cys Ser
                 185                 190                 195

 Leu Asp Glu Pro Ser His Thr
                 200

<210> 6124
<211> 936
<212> DNA
<213> Homo sapien

<400> 6124
 gagggcgcga tcctggcgtc ccccgacggc ctggggcccc aatccagagg 50

 cctgggtggg aggggaccaa gggtgtagta aggaagcgcc ttttgctgga 100

 gggcaacgga ccggggcggg gagtcgggag accagagtgg gaggaaggcg 150

 gggagtccag gttccgcccc ggagccgact tcctcctggt cggcggctgc 200

 agcggggtga gcggcggcag cggccgggga tcctggagcc atggggcgcg 250

 cgcgcgacgc catcctggat gcgctggaga acctgaccgc cgaggagctc 300

 aagaagttca agctgaagct gctgtcggtg ccgctgcgcg agggctacgg 350

 gcgcatcccg cggggcgcgc tgctgtccat ggacgccttg gacctcaccg 400

 acaagctggt cagcttctac ctggagacct acggcgccga gctcaccgct 450

 aacgtgctgc gcgacatggg cctgcaggag atggccgggc agctgcaggc 500

 ggccacgcac cagggctctg gagccgcgcc agctgggatc caggcccctc 550

 ctcagtcggc agccaagcca ggcctgcact ttatagacca gcaccgggct 600

 gcgcttatcg cgagggtcac aaacgttgag tggctgctgg atgctctgta 650

 cgggaaggtc ctgacggatg agcagtacca ggcagtgcgg gccgagccca 700

 ccaacccaag caagatgcgg aagctcttca gtttcacacc agcctggaac 750

 tggacctgca aggacttgct cctccaggcc ctaagggagt cccagtccta 800

 cctggtggag gacctggagc ggagctgagg ctccttccca gcaacactcc 850

 ggtcagcccc tggcaatccc accaaatcat cctgaatctg atctttttat 900

 acacaatata cgaaaagcca gcttgaaaaa aaaaaa 936

<210> 6125
<211> 195
<212> PRT
<213> Homo sapien

<400> 6125
 Met Gly Arg Ala Arg Asp Ala Ile Leu Asp Ala Leu Glu Asn Leu
   1               5                  10                  15

 Thr Ala Glu Glu Leu Lys Lys Phe Lys Leu Lys Leu Leu Ser Val
                  20                  25                  30

 Pro Leu Arg Glu Gly Tyr Gly Arg Ile Pro Arg Gly Ala Leu Leu
                  35                  40                  45

 Ser Met Asp Ala Leu Asp Leu Thr Asp Lys Leu Val Ser Phe Tyr
                  50                  55                  60

 Leu Glu Thr Tyr Gly Ala Glu Leu Thr Ala Asn Val Leu Arg Asp
                  65                  70                  75

 Met Gly Leu Gln Glu Met Ala Gly Gln Leu Gln Ala Ala Thr His
                  80                  85                  90

 Gln Gly Ser Gly Ala Ala Pro Ala Gly Ile Gln Ala Pro Pro Gln
                  95                 100                 105

 Ser Ala Ala Lys Pro Gly Leu His Phe Ile Asp Gln His Arg Ala
                 110                 115                 120

 Ala Leu Ile Ala Arg Val Thr Asn Val Glu Trp Leu Leu Asp Ala
                 125                 130                 135

 Leu Tyr Gly Lys Val Leu Thr Asp Glu Gln Tyr Gln Ala Val Arg
                 140                 145                 150

 Ala Glu Pro Thr Asn Pro Ser Lys Met Arg Lys Leu Phe Ser Phe
                 155                 160                 165

 Thr Pro Ala Trp Asn Trp Thr Cys Lys Asp Leu Leu Leu Gln Ala
                 170                 175                 180

 Leu Arg Glu Ser Gln Ser Tyr Leu Val Glu Asp Leu Glu Arg Ser
                 185                 190                 195

<210> 6126
<211> 396
<212> DNA
<213> Homo sapien

<400> 6126
 actccgcctt ccacgtgcac ccactgcctc ttcccttctc gcttgggaac 50

 tctagtctcg cctcgggttg caatggaccc caactgctcc tgtgccgctg 100

 gtgtctcctg cacctgcgcc agctcctgca agtgcaaaga gtgcaaatgc 150

 acctcctgca agaagagctg ctgctcctgc tgccctgtgg gctgtgccaa 200

 gtgtgcccaa ggctgcatct gcaaaggggc atcggagaag tgcagctgct 250

 gcgcctgatg tcgggacagc cctgctccca agtacaaata gagtgacccg 300

 taaaatctag gattttttgt tttttgctac aatcttgacc cctttgctac 350

 attccctttt ttctgtgaaa tatgtgaata ataattaaac acttag 396

<210> 6127
<211> 61
<212> PRT
<213> Homo sapien

<400> 6127
 Met Asp Pro Asn Cys Ser Cys Ala Ala Gly Val Ser Cys Thr Cys
   1               5                  10                  15

 Ala Ser Ser Cys Lys Cys Lys Glu Cys Lys Cys Thr Ser Cys Lys
                  20                  25                  30

 Lys Ser Cys Cys Ser Cys Cys Pro Val Gly Cys Ala Lys Cys Ala
                  35                  40                  45

 Gln Gly Cys Ile Cys Lys Gly Ala Ser Glu Lys Cys Ser Cys Cys
                  50                  55                  60

 Ala


<210> 6128
<211> 3664
<212> DNA
<213> Homo sapien

<400> 6128
 gcgctaggta gagcgccggg acctgtgaca gggctggtag cagcgcagag 50

 gaaaggcggc ttttagccag gtatttcagt gtctgtagac aagatggaat 100

 catctccatt taatagacgg caatggacct cactatcatt gagggtaaca 150

 gccaaagaac tttctcttgt caacaagaac aagtcatcgg ctattgtgga 200

 aatattctcc aagtaccaga aagcagctga agaaacaaac atggagaaga 250

 agagaagtaa caccgaaaat ctctcccagc actttagaaa ggggaccctg 300

 actgtgttaa agaagaagtg ggagaaccca gggctgggag cagagtctca 350

 cacagactct ctacggaaca gcagcactga gattaggcac agagcagacc 400

 atcctcctgc tgaagtgaca agccacgctg cttctggagc caaagctgac 450

 caagaagaac aaatccaccc cagatctaga ctcaggtcac ctcctgaagc 500

 cctcgttcag ggtcgatatc cccacatcaa ggacggtgag gatcttaaag 550

 accactcaac agaaagtaaa aaaatggaaa attgtctagg agaatccagg 600

 catgaagtag aaaaatcaga aatcagtgaa aacacagatg cttcgggcaa 650

 aatagagaaa tataatgttc cgctgaacag gcttaagatg atgtttgaga 700

 aaggtgaacc aactcaaact aagattctcc gggcccaaag ccgaagtgca 750

 agtggaagga agatctctga aaacagctat tctctagatg acctggaaat 800

 aggcccaggt cagttgtcat cttctacatt tgactcggag aaaaatgaga 850

 gtagacgaaa tctggaactt ccacgcctct cagaaacctc tataaaggat 900

 cgaatggcca agtaccaggc agctgtgtcc aaacaaagca gctcaaccaa 950

 ctatacaaat gagctgaaag ccagtggtgg cgaaatcaaa attcataaaa 1000

 tggagcaaaa ggagaatgtg cccccaggtc ctgaggtctg catcacccat 1050

 caggaagggg aaaagatttc tgcaaatgag aatagcctgg cagtccgttc 1100

 cacccctgcc gaagatgact cccgtgactc ccaggttaag agtgaggttc 1150

 aacagcctgt ccatcccaag ccactaagtc cagattccag agcctccagt 1200

 ctttctgaaa gttctcctcc caaagcaatg aagaagtttc aggcacctgc 1250

 aagagagacc tgcgtggaat gtcagaagac agtctatcca atggagcgtc 1300

 tcttggccaa ccagcaggtg tttcacatca gctgcttccg ttgctcctat 1350

 tgcaacaaca aactcagtct aggaacatat gcatctttac atggaagaat 1400

 ctattgtaag cctcacttca atcaactctt taaatctaag ggcaactatg 1450

 atgaaggctt tgggcacaga ccacacaagg atctatgggc aagcaaaaat 1500

 gaaaacgaag agattttgga gagaccagcc cagcttgcaa atgcaaggga 1550

 gacccctcac agcccagggg tagaagatgc ccctattgct aaggtgggtg 1600

 tcctggctgc aagtatggaa gccaaggcct cctctcagca ggagaaggaa 1650

 gacaagccag ctgaaaccaa gaagctgagg atcgcctggc caccccccac 1700

 tgaacttgga agttcaggaa gtgccttgga ggaagggatc aaaatgtcaa 1750

 agcccaaatg gcctcctgaa gacgaaatca gcaagcccga agttcctgag 1800

 gatgtcgatc tagatctgaa gaagctaaga cgatcttctt cactgaagga 1850

 aagaagccgc ccattcactg tagcagcttc atttcaaagc acctctgtca 1900

 agagcccaaa aactgtgtcc ccacctatca ggaaaggctg gagcatgtca 1950

 gagcagagtg aagagtctgt gggtggaaga gttgcagaaa ggaaacaagt 2000

 ggaaaatgcc aaggcttcta agaagaatgg gaatgtggga aaaacaacct 2050

 ggcaaaacaa agaatctaaa ggagagacag ggaagagaag taaggaaggt 2100

 catagtttgg agatggagaa tgagaatctt gtagaaaatg gtgcagactc 2150

 cgatgaagat gataacagct tcctcaaaca acaatctcca caagaaccca 2200

 agtctctgaa ttggtcgagt tttgtagaca acacctttgc tgaagaattc 2250

 actactcaga atcagaaatc ccaggatgtg gaactctggg agggagaagt 2300

 ggtcaaagag ctctctgtgg aagaacagat aaagagaaat cggtattatg 2350

 atgaggatga ggatgaagag tgacaaattg caatgatgct gggccttaaa 2400

 ttcatgttag tgttagcgag ccactgccct ttgtcaaaat gtgatgcaca 2450

 taagcaggta tcccagcatg aaatgtaatt tacttggaag taactttgga 2500

 aaagaattcc ttcttaaaat caaaaacaaa acaaaaaaac acaaaaaaca 2550

 cattctaaat actagagata actttactta aattcttcat tttagcagtg 2600

 atgatatgcg taagtgctgt aaggcttgta actggggaaa tattccacct 2650

 gataatagcc cagattctac tgtattccca aaaggcaata ttaaggtaga 2700

 tagatgatta gtagtatatt gttacacact attttggaat tagagaacat 2750

 acagaaggaa tttaggggct taaacattac gactgaatgc actttagtat 2800

 aaagggcaca gtttgtatat ttttaaatga ataccaattt aattttttag 2850

 tatttacctg ttaagagatt atttagtctt taaatttttt aggttaattt 2900

 tcttgctgtg atatatatga ggaatttact actttatgtc ctgctctcta 2950

 aactacatcc tgaactcgac gtcctgaggt ataatacaac agagcacttt 3000

 ttgaggcaat tgaaaaacca acctacactc ttcggtgctt agagagatct 3050

 gctgtctccc aaataagctt ttgtatctgc cagtgaattt actgtactcc 3100

 aaatgattgc tttcttttct ggtgatatct gtgcttctca taattactga 3150

 aagctgcaat attttagtaa taccttcggg atcactgtcc cccatcttcc 3200

 gtgttagagc aaagtgaaga gtttaaagga ggaagaagaa agaactgtct 3250

 tacaccactt gagctcagac ctctaaaccc tgtatttccc ttatgatgtc 3300

 ccctttttga gacactaatt tttaaatact tactagctct gaaatatatt 3350

 gatttttatc acagtattct cagggtgaaa ttaaaccaac tataggcctt 3400

 tttcttggga tgattttcta gtcttaaggt ttggggacat tataaacttg 3450

 agtacatttg ttgtacacag ttgatattcc aaattgtatg gatgggaggg 3500

 agaggtgtct taagctgtag gcttttcttt gtactgcatt tatagagatt 3550

 tagctttaat attttttaga gatgtaaaac attctgcttt cttagtctta 3600

 cctagtctga aacattttta ttcaataaag attttaatta aaatttgaaa 3650

 aaaaaaaaaa aaaa 3664

<210> 6129
<211> 759
<212> PRT
<213> Homo sapien

<400> 6129
 Met Glu Ser Ser Pro Phe Asn Arg Arg Gln Trp Thr Ser Leu Ser
   1               5                  10                  15

 Leu Arg Val Thr Ala Lys Glu Leu Ser Leu Val Asn Lys Asn Lys
                  20                  25                  30

 Ser Ser Ala Ile Val Glu Ile Phe Ser Lys Tyr Gln Lys Ala Ala
                  35                  40                  45

 Glu Glu Thr Asn Met Glu Lys Lys Arg Ser Asn Thr Glu Asn Leu
                  50                  55                  60

 Ser Gln His Phe Arg Lys Gly Thr Leu Thr Val Leu Lys Lys Lys
                  65                  70                  75

 Trp Glu Asn Pro Gly Leu Gly Ala Glu Ser His Thr Asp Ser Leu
                  80                  85                  90

 Arg Asn Ser Ser Thr Glu Ile Arg His Arg Ala Asp His Pro Pro
                  95                 100                 105

 Ala Glu Val Thr Ser His Ala Ala Ser Gly Ala Lys Ala Asp Gln
                 110                 115                 120

 Glu Glu Gln Ile His Pro Arg Ser Arg Leu Arg Ser Pro Pro Glu
                 125                 130                 135

 Ala Leu Val Gln Gly Arg Tyr Pro His Ile Lys Asp Gly Glu Asp
                 140                 145                 150

 Leu Lys Asp His Ser Thr Glu Ser Lys Lys Met Glu Asn Cys Leu
                 155                 160                 165

 Gly Glu Ser Arg His Glu Val Glu Lys Ser Glu Ile Ser Glu Asn
                 170                 175                 180

 Thr Asp Ala Ser Gly Lys Ile Glu Lys Tyr Asn Val Pro Leu Asn
                 185                 190                 195

 Arg Leu Lys Met Met Phe Glu Lys Gly Glu Pro Thr Gln Thr Lys
                 200                 205                 210

 Ile Leu Arg Ala Gln Ser Arg Ser Ala Ser Gly Arg Lys Ile Ser
                 215                 220                 225

 Glu Asn Ser Tyr Ser Leu Asp Asp Leu Glu Ile Gly Pro Gly Gln
                 230                 235                 240

 Leu Ser Ser Ser Thr Phe Asp Ser Glu Lys Asn Glu Ser Arg Arg
                 245                 250                 255

 Asn Leu Glu Leu Pro Arg Leu Ser Glu Thr Ser Ile Lys Asp Arg
                 260                 265                 270

 Met Ala Lys Tyr Gln Ala Ala Val Ser Lys Gln Ser Ser Ser Thr
                 275                 280                 285

 Asn Tyr Thr Asn Glu Leu Lys Ala Ser Gly Gly Glu Ile Lys Ile
                 290                 295                 300

 His Lys Met Glu Gln Lys Glu Asn Val Pro Pro Gly Pro Glu Val
                 305                 310                 315

 Cys Ile Thr His Gln Glu Gly Glu Lys Ile Ser Ala Asn Glu Asn
                 320                 325                 330

 Ser Leu Ala Val Arg Ser Thr Pro Ala Glu Asp Asp Ser Arg Asp
                 335                 340                 345

 Ser Gln Val Lys Ser Glu Val Gln Gln Pro Val His Pro Lys Pro
                 350                 355                 360

 Leu Ser Pro Asp Ser Arg Ala Ser Ser Leu Ser Glu Ser Ser Pro
                 365                 370                 375

 Pro Lys Ala Met Lys Lys Phe Gln Ala Pro Ala Arg Glu Thr Cys
                 380                 385                 390

 Val Glu Cys Gln Lys Thr Val Tyr Pro Met Glu Arg Leu Leu Ala
                 395                 400                 405

 Asn Gln Gln Val Phe His Ile Ser Cys Phe Arg Cys Ser Tyr Cys
                 410                 415                 420

 Asn Asn Lys Leu Ser Leu Gly Thr Tyr Ala Ser Leu His Gly Arg
                 425                 430                 435

 Ile Tyr Cys Lys Pro His Phe Asn Gln Leu Phe Lys Ser Lys Gly
                 440                 445                 450

 Asn Tyr Asp Glu Gly Phe Gly His Arg Pro His Lys Asp Leu Trp
                 455                 460                 465

 Ala Ser Lys Asn Glu Asn Glu Glu Ile Leu Glu Arg Pro Ala Gln
                 470                 475                 480

 Leu Ala Asn Ala Arg Glu Thr Pro His Ser Pro Gly Val Glu Asp
                 485                 490                 495

 Ala Pro Ile Ala Lys Val Gly Val Leu Ala Ala Ser Met Glu Ala
                 500                 505                 510

 Lys Ala Ser Ser Gln Gln Glu Lys Glu Asp Lys Pro Ala Glu Thr
                 515                 520                 525

 Lys Lys Leu Arg Ile Ala Trp Pro Pro Pro Thr Glu Leu Gly Ser
                 530                 535                 540

 Ser Gly Ser Ala Leu Glu Glu Gly Ile Lys Met Ser Lys Pro Lys
                 545                 550                 555

 Trp Pro Pro Glu Asp Glu Ile Ser Lys Pro Glu Val Pro Glu Asp
                 560                 565                 570

 Val Asp Leu Asp Leu Lys Lys Leu Arg Arg Ser Ser Ser Leu Lys
                 575                 580                 585

 Glu Arg Ser Arg Pro Phe Thr Val Ala Ala Ser Phe Gln Ser Thr
                 590                 595                 600

 Ser Val Lys Ser Pro Lys Thr Val Ser Pro Pro Ile Arg Lys Gly
                 605                 610                 615

 Trp Ser Met Ser Glu Gln Ser Glu Glu Ser Val Gly Gly Arg Val
                 620                 625                 630

 Ala Glu Arg Lys Gln Val Glu Asn Ala Lys Ala Ser Lys Lys Asn
                 635                 640                 645

 Gly Asn Val Gly Lys Thr Thr Trp Gln Asn Lys Glu Ser Lys Gly
                 650                 655                 660

 Glu Thr Gly Lys Arg Ser Lys Glu Gly His Ser Leu Glu Met Glu
                 665                 670                 675

 Asn Glu Asn Leu Val Glu Asn Gly Ala Asp Ser Asp Glu Asp Asp
                 680                 685                 690

 Asn Ser Phe Leu Lys Gln Gln Ser Pro Gln Glu Pro Lys Ser Leu
                 695                 700                 705

 Asn Trp Ser Ser Phe Val Asp Asn Thr Phe Ala Glu Glu Phe Thr
                 710                 715                 720

 Thr Gln Asn Gln Lys Ser Gln Asp Val Glu Leu Trp Glu Gly Glu
                 725                 730                 735

 Val Val Lys Glu Leu Ser Val Glu Glu Gln Ile Lys Arg Asn Arg
                 740                 745                 750

 Tyr Tyr Asp Glu Asp Glu Asp Glu Glu
                 755

<210> 6130
<211> 3195
<212> DNA
<213> Homo sapien

<400> 6130
 agaggcttcc ctggctggtg cctgagcccg gcgtccctcg ccccccgccc 50

 tccccgcatc cctctcctcc ctcgcgcctg gccctgtggc tcttcctccc 100

 tccctccttc cccccccccc cacccctcgc ccgctgcctc cctcggccca 150

 gccagctgtg ccggcgtttg ttggctgccc tgcgcccggc cctccagcca 200

 gccttctgcc ggccccgccg cgatggaggt gccccagccg gagcccgcgc 250

 caggctcggc tctcagtcca gcaggcgtgt gcggtggcgc ccagcgtccg 300

 ggccacctcc cgggcctcct gctgggatct catggcctcc tggggtcccc 350

 ggtgcgggcg gccgcttcct cgccggtcac caccctcacc cagaccatgc 400

 acgacctcgc cgggctcggc agccgcagcc gcctgacgca cctatccctg 450

 tctcgacggg catccgaatc ctccctgtcg tctgaatcct ccgaatcttc 500

 tgatgcaggt ctctgcatgg attcccccag ccctatggac ccccacatgg 550

 cggagcagac gtttgaacag gccatccagg cagccagccg gatcattcga 600

 aacgagcagt ttgccatcag acgcttccag tctatgccgg tgaggctgct 650

 gggccacagc cccgtgcttc ggaacatcac caactcccag gcgcccgacg 700

 gccggaggaa gagcgaggcg ggcagtggag ctgccagcag ctctggggaa 750

 gacaaggaga atgtgcgctt ctggaaggcc ggggtgggag ctctccggga 800

 agaggagggg gcatgctggg gtggttccct ggcatgtgag gaccctcctc 850

 tcccatcttg gctgcaggat ggatttgtct tcaagatgcc atggaagccc 900

 acacatccca gctccaccca tgctctggca gagtgggcca gccgcaggga 950

 agcctttgcc cagagaccca gctcggcccc cgacctgatg tgtctcagtc 1000

 ctgaccggaa gatggaagtg gaggagctca gccccctggc cctaggtcgc 1050

 ttctctctga cccctgcaga gggggatact gaggaagatg atggatttgt 1100

 ggacatccta gagagtgact taaaggatga tgatgcagtt cccccaggca 1150

 tggagagtct cattagtgcc ccactggtca agaccttgga aaaggaagag 1200

 gaaaaggacc tcgtcatgta cagcaagtgc cagcggctct tccgctctcc 1250

 gtccatgccc tgcagcgtga tccggcccat cctcaagagg ctggagcggc 1300

 cccaggacag ggacacgccc gtgcagaata agcggaggcg gagcgtgacc 1350

 cctcctgagg agcagcagga ggctgaggaa cctaaagccc gcgtcctccg 1400

 ctcaaaatca ctgtgtcacg atgagatcga gaacctcctg gacagtgacc 1450

 accgagagct gattggagat tactctaagg ccttcctcct acagacagta 1500

 gacggaaagc accaagacct caagtacatc tcaccagaaa cgatggtggc 1550

 cctattgacg ggcaagttca gcaacatcgt ggataagttt gtgattgtag 1600

 actgcagata cccctatgaa tatgaaggcg ggcacatcaa gactgcggtg 1650

 aacttgcccc tggaacgcga cgccgagagc ttcctactga agagccccat 1700

 cgcgccctgt agcctggaca agagagtcat cctcattttc cactgtgaat 1750

 tctcatctga gcgtgggccc cgcatgtgcc gtttcatcag ggaacgagac 1800

 cgtgctgtca acgactaccc cagcctctac taccctgaga tgtatatcct 1850

 gaaaggcggc tacaaggagt tcttccctca gcacccgaac ttctgtgaac 1900

 cccaggacta ccggcccatg aaccacgagg ccttcaagga tgagctaaag 1950

 accttccgcc tcaagactcg cagctgggct ggggagcgga gccggcggga 2000

 gctctgtagc cggctgcagg accagtgagg ggcctgcgcc agtcctgcta 2050

 cctcccttgc ctttcgaggc ctgaagccag ctgccctatg ggcctgccgg 2100

 gctgagggcc tgctggaggc ctcaggtgct gtccatggga aagatggtgt 2150

 ggtgtcctgc ctgtctgccc cagcccagat tcccctgtgt catcccatca 2200

 ttttccatat cctggtgccc cccacccctg gaagagccca gtctgttgag 2250

 ttagttaagt tgggttaata ccagcttaaa ggcagtattt tgtgtcctcc 2300

 aggagcttct tgtttccttg ttagggttaa cccttcatct tcctgtgtcc 2350

 tgaaacgctc ctttgtgtgt gtgtcagctg aggctgggga gagccgtggt 2400

 ccctgaggat gggtcagagc taaactcctt cctggcctga gagtcagctc 2450

 tctgccctgt gtacttcccg ggccagggct gcccctaatc tctgtaggaa 2500

 ccgtggtatg tctgccatgt tgcccctttc tcttttcccc tttcctgtcc 2550

 caccatacga gcacctccag cctgaacaga agctcttact ctttcctatt 2600

 tcagtgttac ctgtgtgctt ggtctgtttg actttacgcc catctcagga 2650

 cacttccgta gactgtttag gttcccctgt caaatatcag ttacccactc 2700

 ggtcccagtt ttgttgcccc agaaagggat gttattatcc ttgggggctc 2750

 ccagggcaag ggttaaggcc tgaatcatga gcctgctgga agcccagccc 2800

 ctactgctgt gaaccctggg gcctgactgc tcagaacttg ctgctgtctt 2850

 gttgcggatg gatggaaggt tggatggatg ggtggatggc cgtggatggc 2900

 cgtggatgcg cagtgccttg catacccaaa ccaggtggga gcgttttgtt 2950

 gagcatgaca cctgcagcag gaatatatgt gtgcctattt gtgtggacaa 3000

 aaatatttac acttagggtt tggagctatt caagaggaaa tgtcacagaa 3050

 gcagctaaac caaggactga gcaccctctg gattctgaat ctcaagatgg 3100

 gggcagggct gtgcttgaag gccctgctga gtcatctgtt agggccttgg 3150

 ttcaataaag cactgagcaa gttgagaaaa aaaaaaaaaa aaaaa 3195

<210> 6131
<211> 601
<212> PRT
<213> Homo sapien

<400> 6131
 Met Glu Val Pro Gln Pro Glu Pro Ala Pro Gly Ser Ala Leu Ser
   1               5                  10                  15

 Pro Ala Gly Val Cys Gly Gly Ala Gln Arg Pro Gly His Leu Pro
                  20                  25                  30

 Gly Leu Leu Leu Gly Ser His Gly Leu Leu Gly Ser Pro Val Arg
                  35                  40                  45

 Ala Ala Ala Ser Ser Pro Val Thr Thr Leu Thr Gln Thr Met His
                  50                  55                  60

 Asp Leu Ala Gly Leu Gly Ser Arg Ser Arg Leu Thr His Leu Ser
                  65                  70                  75

 Leu Ser Arg Arg Ala Ser Glu Ser Ser Leu Ser Ser Glu Ser Ser
                  80                  85                  90

 Glu Ser Ser Asp Ala Gly Leu Cys Met Asp Ser Pro Ser Pro Met
                  95                 100                 105

 Asp Pro His Met Ala Glu Gln Thr Phe Glu Gln Ala Ile Gln Ala
                 110                 115                 120

 Ala Ser Arg Ile Ile Arg Asn Glu Gln Phe Ala Ile Arg Arg Phe
                 125                 130                 135

 Gln Ser Met Pro Val Arg Leu Leu Gly His Ser Pro Val Leu Arg
                 140                 145                 150

 Asn Ile Thr Asn Ser Gln Ala Pro Asp Gly Arg Arg Lys Ser Glu
                 155                 160                 165

 Ala Gly Ser Gly Ala Ala Ser Ser Ser Gly Glu Asp Lys Glu Asn
                 170                 175                 180

 Val Arg Phe Trp Lys Ala Gly Val Gly Ala Leu Arg Glu Glu Glu
                 185                 190                 195

 Gly Ala Cys Trp Gly Gly Ser Leu Ala Cys Glu Asp Pro Pro Leu
                 200                 205                 210

 Pro Ser Trp Leu Gln Asp Gly Phe Val Phe Lys Met Pro Trp Lys
                 215                 220                 225

 Pro Thr His Pro Ser Ser Thr His Ala Leu Ala Glu Trp Ala Ser
                 230                 235                 240

 Arg Arg Glu Ala Phe Ala Gln Arg Pro Ser Ser Ala Pro Asp Leu
                 245                 250                 255

 Met Cys Leu Ser Pro Asp Arg Lys Met Glu Val Glu Glu Leu Ser
                 260                 265                 270

 Pro Leu Ala Leu Gly Arg Phe Ser Leu Thr Pro Ala Glu Gly Asp
                 275                 280                 285

 Thr Glu Glu Asp Asp Gly Phe Val Asp Ile Leu Glu Ser Asp Leu
                 290                 295                 300

 Lys Asp Asp Asp Ala Val Pro Pro Gly Met Glu Ser Leu Ile Ser
                 305                 310                 315

 Ala Pro Leu Val Lys Thr Leu Glu Lys Glu Glu Glu Lys Asp Leu
                 320                 325                 330

 Val Met Tyr Ser Lys Cys Gln Arg Leu Phe Arg Ser Pro Ser Met
                 335                 340                 345

 Pro Cys Ser Val Ile Arg Pro Ile Leu Lys Arg Leu Glu Arg Pro
                 350                 355                 360

 Gln Asp Arg Asp Thr Pro Val Gln Asn Lys Arg Arg Arg Ser Val
                 365                 370                 375

 Thr Pro Pro Glu Glu Gln Gln Glu Ala Glu Glu Pro Lys Ala Arg
                 380                 385                 390

 Val Leu Arg Ser Lys Ser Leu Cys His Asp Glu Ile Glu Asn Leu
                 395                 400                 405

 Leu Asp Ser Asp His Arg Glu Leu Ile Gly Asp Tyr Ser Lys Ala
                 410                 415                 420

 Phe Leu Leu Gln Thr Val Asp Gly Lys His Gln Asp Leu Lys Tyr
                 425                 430                 435

 Ile Ser Pro Glu Thr Met Val Ala Leu Leu Thr Gly Lys Phe Ser
                 440                 445                 450

 Asn Ile Val Asp Lys Phe Val Ile Val Asp Cys Arg Tyr Pro Tyr
                 455                 460                 465

 Glu Tyr Glu Gly Gly His Ile Lys Thr Ala Val Asn Leu Pro Leu
                 470                 475                 480

 Glu Arg Asp Ala Glu Ser Phe Leu Leu Lys Ser Pro Ile Ala Pro
                 485                 490                 495

 Cys Ser Leu Asp Lys Arg Val Ile Leu Ile Phe His Cys Glu Phe
                 500                 505                 510

 Ser Ser Glu Arg Gly Pro Arg Met Cys Arg Phe Ile Arg Glu Arg
                 515                 520                 525

 Asp Arg Ala Val Asn Asp Tyr Pro Ser Leu Tyr Tyr Pro Glu Met
                 530                 535                 540

 Tyr Ile Leu Lys Gly Gly Tyr Lys Glu Phe Phe Pro Gln His Pro
                 545                 550                 555

 Asn Phe Cys Glu Pro Gln Asp Tyr Arg Pro Met Asn His Glu Ala
                 560                 565                 570

 Phe Lys Asp Glu Leu Lys Thr Phe Arg Leu Lys Thr Arg Ser Trp
                 575                 580                 585

 Ala Gly Glu Arg Ser Arg Arg Glu Leu Cys Ser Arg Leu Gln Asp
                 590                 595                 600

 Gln


<210> 6132
<211> 4799
<212> DNA
<213> Homo sapien

<400> 6132
 ccgccgccac tgccgtcggg taaggtccca gcacggacat ggcctcgcgc 50

 ggcgcccgcc cgggcccgag tcccccgcgc cccgctttgt agccccccgg 100

 cggagaggcg gcctcgacgg tgcggacggc gcagacggcc gggcgggcgg 150

 catggaggcg gcgcatctgc tcccggccgc cgacgtgctg cgccacttct 200

 cggtgacagc cgagggcggc ctgagcccgg cgcaggtgac cggcgcgcgg 250

 gagcgctacg gccccaacga gctcccgagt gaggaaggga agtccctgtg 300

 ggagctggtg ctggaacagt ttgaggacct cctggtgcgc atcctgctgc 350

 tggctgccct tgtctccttt gtcctggcct ggttcgagga gggcgaggag 400

 accacgaccg ccttcgtgga gcccctggtc atcatgctga tcctcgtggc 450

 caacgccatt gtgggcgtgt ggcaggaacg caacgccgag agtgccatcg 500

 aggccctgaa ggagtatgag cctgagatgg gcaaggtgat ccgctcggac 550

 cgcaagggcg tgcagaggat ccgtgcccgg gacatcgtcc caggggacat 600

 tgtagaagtg gcagtggggg acaaagtgcc tgctgacctc cgcctcatcg 650

 agatcaagtc caccacgctg cgagtggacc agtccatcct gacgggtgaa 700

 tctgtgtccg tgaccaagca cacagaggcc atcccagacc ccagagctgt 750

 gaaccaggac aagaagaaca tgctgttttc tggcaccaat atcacatcgg 800

 gcaaagcggt gggtgtggcc gtggccaccg gcctgcacac ggagctgggc 850

 aagatccgga gccagatggc ggcagtcgag cccgagcgga cgccgctgca 900

 gcgcaagctg gacgagtttg gacggcagct gtcccacgcc atctctgtga 950

 tctgcgtggc cgtgtgggtc atcaacatcg gccacttcgc cgacccggcc 1000

 cacggtggct cctggctgcg tggcgctgtc tactacttca agatcgccgt 1050

 ggccctggcg gtggcggcca tccccgaggg cctcccggct gtcatcacta 1100

 catgcctggc actgggcacg cggcgcatgg cacgcaagaa cgccatcgtg 1150

 cgaagcctgc cgtccgtgga gaccctgggc tgcacctcag tcatctgctc 1200

 cgacaagacg ggcacgctca ccaccaatca gatgtctgtc tgccggatgt 1250

 tcgtggtagc cgaggccgat gcgggctcct gccttttgca cgagttcacc 1300

 atctcgggta ccacgtatac ccccgagggc gaagtgcggc agggggatca 1350

 gcctgtgcgc tgcggccagt tcgacgggct ggtggagctg gcgaccatct 1400

 gcgccctgtg caacgactcg gctctggact acaacgaggc caagggtgtg 1450

 tatgagaagg tgggagaggc cacggagaca gctctgactt gcctggtgga 1500

 gaagatgaac gtgttcgaca ccgacctgca ggctctgtcc cgggtggagc 1550

 gagctggcgc ctgtaacacg gtcatcaagc agctgatgcg gaaggagttc 1600

 accctggagt tctcccgaga ccggaaatcc atgtccgtgt actgcacgcc 1650

 cacccgccct caccctactg gccagggcag caagatgttt gtgaaggggg 1700

 ctcctgagag tgtgatcgag cgctgtagct cagtccgcgt ggggagccgc 1750

 acagcacccc tgacccccac ctccagggag cagatcctgg caaagatccg 1800

 ggattggggc tcaggctcag acacgctgcg ctgcctggca ctggccaccc 1850

 gggacgcgcc cccaaggaag gaggacatgg agctggacga ctgcagcaag 1900

 tttgtgcagt acgagacgga cctgaccttc gtgggctgcg taggcatgct 1950

 ggacccgccg cgacctgagg tggctgcctg catcacacgc tgctaccagg 2000

 cgggcatccg cgtggtcatg atcacggggg ataacaaagg cactgccgtg 2050

 gccatctgcc gcaggcttgg catctttggg gacacggaag acgtggcggg 2100

 caaggcctac acgggccgcg agtttgatga cctcagcccc gagcagcagc 2150

 gccaggcctg ccgcaccgcc cgctgcttcg cccgcgtgga gcccgcacac 2200

 aagtcccgca tcgtggagaa cctgcagtcc tttaacgaga tcactgctat 2250

 gactggcgat ggagtgaacg acgcaccagc cctgaagaaa gcagagatcg 2300

 gcatcgccat gggctcaggc acggccgtgg ccaagtcggc ggcagagatg 2350

 gtgctgtcag atgacaactt tgcctccatc gtggctgcgg tggaggaggg 2400

 ccgggccatc tacagcaaca tgaagcaatt catccgctac ctcatctcct 2450

 ccaatgttgg cgaggtcgtc tgcatcttcc tcacggcaat tctgggcctg 2500

 cccgaagccc tgatccctgt gcagctgctc tgggtgaacc tggtgacaga 2550

 cggcctacct gccacggctc tgggcttcaa cccgccagac ctggacatca 2600

 tggagaagct gccccggagc ccccgagaag ccctcatcag tggctggctc 2650

 ttcttccgat acctggctat cggagtgtac gtaggcctgg ccacagtggc 2700

 tgccgccacc tggtggtttg tgtatgacgc cgagggacct cacatcaact 2750

 tctaccagct gaggaacttc ctgaagtgct ccgaagacaa cccgctcttt 2800

 gccggcatcg actgtgaggt gttcgagtca cgcttcccca ccaccatggc 2850

 cttgtccgtg ctcgtgacca ttgaaatgtg caatgccctc aacagcgtct 2900

 cggagaacca gtcgctgctg cggatgccgc cctggatgaa cccctggctg 2950

 ctggtggctg tggccatgtc catggccctg cacttcctca tcctgctcgt 3000

 gccgcccctg cctctcattt tccaggtgac cccactgagc gggcgccagt 3050

 gggtggtggt gctccagata tctctgcctg tcatcctgct ggatgaggcc 3100

 ctcaagtacc tgtcccggaa ccacatgcac gcctgtcttt atccaggcct 3150

 tctcaggaca gtctcgcagg cctggagtag gcagccgctg accacctctt 3200

 ggaccccaga ccacaccggg ttggcctctt tgaagaaatg agccagaagt 3250

 gagcgctggg aacagagtgg agtctccggt gtgtacctca gactgatggt 3300

 gcccatgtgt tcgcctccgc cccccaccct tgccaccaca ctcgcccact 3350

 tgcccaccgg gtcccgccgg ataaatgaca ggcccgaggt cagaatggcc 3400

 atccccgggc cccgtcctgg ggtctctgtc cccacttcct tctggcctgg 3450

 gaggtctgta attcctgtct cctggactct cctgggaagt tccctgctct 3500

 gcagctctgg cccaggagct gcaggctggg agggggcagc caagaagccg 3550

 gagctggcag catacccaga gatccggggc ccccccaccc ccaaatcacg 3600

 agtgcagctg gagcttgctc ccccttgttc ggaagctgga cgttcacttg 3650

 gtgactggtg cctctgcact gacggaggac tctgggggtc cttcttaccg 3700

 gctctgacct ctctcttcgt gcctggtctg ggactgggtc agccctgggg 3750

 gatcagaagg ggccatctgg gcccagctgt gtacagcgag ggtgggcagc 3800

 cccctccact ccactctgct tccacaaagt cggctcccga gagctcgagg 3850

 ctgcttctgt ttatatgtgc agggcccggg cgggtgaagg gtcagagaga 3900

 cggacacaag gagccggcag gagggcggag cgaggatgtc ctttcccggg 3950

 agacaagtcg ggaaagcctg gctggactgc ctcagccccg cgcgcctcct 4000

 ggactcaggg ttccccgtcc tgagctcggg agatgttcag agtcacactg 4050

 ccgcccggtc tgccacgcag aggtccaact tgccacccgc gtccctggta 4100

 cctgagacca ccgacatcct caggttcctg accgtggcgc ccttctaccc 4150

 agcccagtgt gcggccgccg cgctgtctgc acagctgggg gcctctgagc 4200

 ctggtgggct tcctggactc ttggcctcac tccttgcccc ctccccacga 4250

 cacccatgag ccgaaaggat gtcactaagg atggctgatt ccccaagggc 4300

 acccgctctc cctccctccc tgctggagga acacgtcata tcagatgaga 4350

 ggaagatggc ctctgatgga cagaattttt ctcttaactc agcttttgct 4400

 actttggcaa aaactagcga ggggtagcag aaacctgcac caaggattgt 4450

 ccctatgtct tggccactcc tagagcgtgt gcagactgat gattttatat 4500

 gtaaatcaag actcacatcc ctttcctagt cccccacatc caaagcccct 4550

 cagcctgcct tgcagaccaa tgggctccat gttctgtagc cccctcccct 4600

 acgcctcacc cctcctccct ctcacaggtt ctgggcggcc agtgagagaa 4650

 acgcagtggg ggaggcaggg agtctggtgc ctgcagagat tctctgcttc 4700

 tttcctgggg ggaggtgggg aggtcttagc aggagcgggc cctgtaccca 4750

 cctgctgacc tgctgtttgg tagagaaata aaggttgtgt gactggggg 4799

<210> 6133
<211> 1029
<212> PRT
<213> Homo sapien

<400> 6133
 Met Glu Ala Ala His Leu Leu Pro Ala Ala Asp Val Leu Arg His
   1               5                  10                  15

 Phe Ser Val Thr Ala Glu Gly Gly Leu Ser Pro Ala Gln Val Thr
                  20                  25                  30

 Gly Ala Arg Glu Arg Tyr Gly Pro Asn Glu Leu Pro Ser Glu Glu
                  35                  40                  45

 Gly Lys Ser Leu Trp Glu Leu Val Leu Glu Gln Phe Glu Asp Leu
                  50                  55                  60

 Leu Val Arg Ile Leu Leu Leu Ala Ala Leu Val Ser Phe Val Leu
                  65                  70                  75

 Ala Trp Phe Glu Glu Gly Glu Glu Thr Thr Thr Ala Phe Val Glu
                  80                  85                  90

 Pro Leu Val Ile Met Leu Ile Leu Val Ala Asn Ala Ile Val Gly
                  95                 100                 105

 Val Trp Gln Glu Arg Asn Ala Glu Ser Ala Ile Glu Ala Leu Lys
                 110                 115                 120

 Glu Tyr Glu Pro Glu Met Gly Lys Val Ile Arg Ser Asp Arg Lys
                 125                 130                 135

 Gly Val Gln Arg Ile Arg Ala Arg Asp Ile Val Pro Gly Asp Ile
                 140                 145                 150

 Val Glu Val Ala Val Gly Asp Lys Val Pro Ala Asp Leu Arg Leu
                 155                 160                 165

 Ile Glu Ile Lys Ser Thr Thr Leu Arg Val Asp Gln Ser Ile Leu
                 170                 175                 180

 Thr Gly Glu Ser Val Ser Val Thr Lys His Thr Glu Ala Ile Pro
                 185                 190                 195

 Asp Pro Arg Ala Val Asn Gln Asp Lys Lys Asn Met Leu Phe Ser
                 200                 205                 210

 Gly Thr Asn Ile Thr Ser Gly Lys Ala Val Gly Val Ala Val Ala
                 215                 220                 225

 Thr Gly Leu His Thr Glu Leu Gly Lys Ile Arg Ser Gln Met Ala
                 230                 235                 240

 Ala Val Glu Pro Glu Arg Thr Pro Leu Gln Arg Lys Leu Asp Glu
                 245                 250                 255

 Phe Gly Arg Gln Leu Ser His Ala Ile Ser Val Ile Cys Val Ala
                 260                 265                 270

 Val Trp Val Ile Asn Ile Gly His Phe Ala Asp Pro Ala His Gly
                 275                 280                 285

 Gly Ser Trp Leu Arg Gly Ala Val Tyr Tyr Phe Lys Ile Ala Val
                 290                 295                 300

 Ala Leu Ala Val Ala Ala Ile Pro Glu Gly Leu Pro Ala Val Ile
                 305                 310                 315

 Thr Thr Cys Leu Ala Leu Gly Thr Arg Arg Met Ala Arg Lys Asn
                 320                 325                 330

 Ala Ile Val Arg Ser Leu Pro Ser Val Glu Thr Leu Gly Cys Thr
                 335                 340                 345

 Ser Val Ile Cys Ser Asp Lys Thr Gly Thr Leu Thr Thr Asn Gln
                 350                 355                 360

 Met Ser Val Cys Arg Met Phe Val Val Ala Glu Ala Asp Ala Gly
                 365                 370                 375

 Ser Cys Leu Leu His Glu Phe Thr Ile Ser Gly Thr Thr Tyr Thr
                 380                 385                 390

 Pro Glu Gly Glu Val Arg Gln Gly Asp Gln Pro Val Arg Cys Gly
                 395                 400                 405

 Gln Phe Asp Gly Leu Val Glu Leu Ala Thr Ile Cys Ala Leu Cys
                 410                 415                 420

 Asn Asp Ser Ala Leu Asp Tyr Asn Glu Ala Lys Gly Val Tyr Glu
                 425                 430                 435

 Lys Val Gly Glu Ala Thr Glu Thr Ala Leu Thr Cys Leu Val Glu
                 440                 445                 450

 Lys Met Asn Val Phe Asp Thr Asp Leu Gln Ala Leu Ser Arg Val
                 455                 460                 465

 Glu Arg Ala Gly Ala Cys Asn Thr Val Ile Lys Gln Leu Met Arg
                 470                 475                 480

 Lys Glu Phe Thr Leu Glu Phe Ser Arg Asp Arg Lys Ser Met Ser
                 485                 490                 495

 Val Tyr Cys Thr Pro Thr Arg Pro His Pro Thr Gly Gln Gly Ser
                 500                 505                 510

 Lys Met Phe Val Lys Gly Ala Pro Glu Ser Val Ile Glu Arg Cys
                 515                 520                 525

 Ser Ser Val Arg Val Gly Ser Arg Thr Ala Pro Leu Thr Pro Thr
                 530                 535                 540

 Ser Arg Glu Gln Ile Leu Ala Lys Ile Arg Asp Trp Gly Ser Gly
                 545                 550                 555

 Ser Asp Thr Leu Arg Cys Leu Ala Leu Ala Thr Arg Asp Ala Pro
                 560                 565                 570

 Pro Arg Lys Glu Asp Met Glu Leu Asp Asp Cys Ser Lys Phe Val
                 575                 580                 585

 Gln Tyr Glu Thr Asp Leu Thr Phe Val Gly Cys Val Gly Met Leu
                 590                 595                 600

 Asp Pro Pro Arg Pro Glu Val Ala Ala Cys Ile Thr Arg Cys Tyr
                 605                 610                 615

 Gln Ala Gly Ile Arg Val Val Met Ile Thr Gly Asp Asn Lys Gly
                 620                 625                 630

 Thr Ala Val Ala Ile Cys Arg Arg Leu Gly Ile Phe Gly Asp Thr
                 635                 640                 645

 Glu Asp Val Ala Gly Lys Ala Tyr Thr Gly Arg Glu Phe Asp Asp
                 650                 655                 660

 Leu Ser Pro Glu Gln Gln Arg Gln Ala Cys Arg Thr Ala Arg Cys
                 665                 670                 675

 Phe Ala Arg Val Glu Pro Ala His Lys Ser Arg Ile Val Glu Asn
                 680                 685                 690

 Leu Gln Ser Phe Asn Glu Ile Thr Ala Met Thr Gly Asp Gly Val
                 695                 700                 705

 Asn Asp Ala Pro Ala Leu Lys Lys Ala Glu Ile Gly Ile Ala Met
                 710                 715                 720

 Gly Ser Gly Thr Ala Val Ala Lys Ser Ala Ala Glu Met Val Leu
                 725                 730                 735

 Ser Asp Asp Asn Phe Ala Ser Ile Val Ala Ala Val Glu Glu Gly
                 740                 745                 750

 Arg Ala Ile Tyr Ser Asn Met Lys Gln Phe Ile Arg Tyr Leu Ile
                 755                 760                 765

 Ser Ser Asn Val Gly Glu Val Val Cys Ile Phe Leu Thr Ala Ile
                 770                 775                 780

 Leu Gly Leu Pro Glu Ala Leu Ile Pro Val Gln Leu Leu Trp Val
                 785                 790                 795

 Asn Leu Val Thr Asp Gly Leu Pro Ala Thr Ala Leu Gly Phe Asn
                 800                 805                 810

 Pro Pro Asp Leu Asp Ile Met Glu Lys Leu Pro Arg Ser Pro Arg
                 815                 820                 825

 Glu Ala Leu Ile Ser Gly Trp Leu Phe Phe Arg Tyr Leu Ala Ile
                 830                 835                 840

 Gly Val Tyr Val Gly Leu Ala Thr Val Ala Ala Ala Thr Trp Trp
                 845                 850                 855

 Phe Val Tyr Asp Ala Glu Gly Pro His Ile Asn Phe Tyr Gln Leu
                 860                 865                 870

 Arg Asn Phe Leu Lys Cys Ser Glu Asp Asn Pro Leu Phe Ala Gly
                 875                 880                 885

 Ile Asp Cys Glu Val Phe Glu Ser Arg Phe Pro Thr Thr Met Ala
                 890                 895                 900

 Leu Ser Val Leu Val Thr Ile Glu Met Cys Asn Ala Leu Asn Ser
                 905                 910                 915

 Val Ser Glu Asn Gln Ser Leu Leu Arg Met Pro Pro Trp Met Asn
                 920                 925                 930

 Pro Trp Leu Leu Val Ala Val Ala Met Ser Met Ala Leu His Phe
                 935                 940                 945

 Leu Ile Leu Leu Val Pro Pro Leu Pro Leu Ile Phe Gln Val Thr
                 950                 955                 960

 Pro Leu Ser Gly Arg Gln Trp Val Val Val Leu Gln Ile Ser Leu
                 965                 970                 975

 Pro Val Ile Leu Leu Asp Glu Ala Leu Lys Tyr Leu Ser Arg Asn
                 980                 985                 990

 His Met His Ala Cys Leu Tyr Pro Gly Leu Leu Arg Thr Val Ser
                 995                1000                1005

 Gln Ala Trp Ser Arg Gln Pro Leu Thr Thr Ser Trp Thr Pro Asp
                1010                1015                1020

 His Thr Gly Leu Ala Ser Leu Lys Lys
                1025

<210> 6134
<211> 1196
<212> DNA
<213> Homo sapien

<400> 6134
 agccgagggc tgcacaaaga ccttcctggc ctgccccaga cagagctgag 50

 gacccctggc cgtgggcttg ggcctcggct tcacaggatg gggctgccag 100

 tgtcctgggc ccctcctgcc ctctgggttc tagggtgctg cgccctgctc 150

 ctctcgctgt gggcgctgtg cacagcctgc cgcaggcccg aggacgctgt 200

 agcccccagg aagagggcgc ggaggcagcg ggcgaggctg cagggcagtg 250

 cgacggcggc ggaagcgtcc ctactgaggc ggacccacct ctgctccctc 300

 agcaagtcgg acaccagact gcacgagctg caccggggcc cgcgcagcag 350

 cagggccctg cggcctgcca gcatggatct cctgcgccca cactggctgg 400

 aggtgtccag ggacatcacc ggaccgcagg cagccccctc tgccttccca 450

 caccaggagc tgccccgggc tctgccggca gctgcagcca ccgcagggtg 500

 cgctggcctc gaggccacct attccaacgt ggggctggcg gcccttcccg 550

 gggtcagcct ggcggccagc cctgtggtgg ccgagtatgc ccgcgtccag 600

 aagcgcaaag ggacccatcg cagtccccaa gagccacagc aggggaagac 650

 tgaggtgacc ccggccgctc aggtggacgt cctgtactcc agggtctgca 700

 agcctaaaag gagggaccca ggacccacca cagacccgct ggaccccaag 750

 ggccagggag cgattctggc cctggcgggt gacctggcct accagaccct 800

 cccgctcagg gccctggatg tgggcagcgg ccccctggaa aacgtgtatg 850

 agagcatccg ggagctgggg gaccctgctg gcaggagcag cacgtgcggg 900

 gctgggacgc cccctgcttc cagctgcccc agcctaggga ggggctggag 950

 acccctccct gcctccctgc cctgaacact caaggacctg tgctccttcc 1000

 tccagagtga ggcccgtccc ccgccccgcc ccgcctcaca gctgacagcg 1050

 ccagtcccag gtccccgggc tgccagcccg tgaggtccgt gaggtcctgg 1100

 ccgctctgac agccgcggcc tccccgggct ccagagaagg cccgcgtcta 1150

 aataaagcgc cagcgcagga tgaaagcgaa aaaaaaaaaa aaaaaa 1196

<210> 6135
<211> 295
<212> PRT
<213> Homo sapien

<400> 6135
 Met Gly Leu Pro Val Ser Trp Ala Pro Pro Ala Leu Trp Val Leu
   1               5                  10                  15

 Gly Cys Cys Ala Leu Leu Leu Ser Leu Trp Ala Leu Cys Thr Ala
                  20                  25                  30

 Cys Arg Arg Pro Glu Asp Ala Val Ala Pro Arg Lys Arg Ala Arg
                  35                  40                  45

 Arg Gln Arg Ala Arg Leu Gln Gly Ser Ala Thr Ala Ala Glu Ala
                  50                  55                  60

 Ser Leu Leu Arg Arg Thr His Leu Cys Ser Leu Ser Lys Ser Asp
                  65                  70                  75

 Thr Arg Leu His Glu Leu His Arg Gly Pro Arg Ser Ser Arg Ala
                  80                  85                  90

 Leu Arg Pro Ala Ser Met Asp Leu Leu Arg Pro His Trp Leu Glu
                  95                 100                 105

 Val Ser Arg Asp Ile Thr Gly Pro Gln Ala Ala Pro Ser Ala Phe
                 110                 115                 120

 Pro His Gln Glu Leu Pro Arg Ala Leu Pro Ala Ala Ala Ala Thr
                 125                 130                 135

 Ala Gly Cys Ala Gly Leu Glu Ala Thr Tyr Ser Asn Val Gly Leu
                 140                 145                 150

 Ala Ala Leu Pro Gly Val Ser Leu Ala Ala Ser Pro Val Val Ala
                 155                 160                 165

 Glu Tyr Ala Arg Val Gln Lys Arg Lys Gly Thr His Arg Ser Pro
                 170                 175                 180

 Gln Glu Pro Gln Gln Gly Lys Thr Glu Val Thr Pro Ala Ala Gln
                 185                 190                 195

 Val Asp Val Leu Tyr Ser Arg Val Cys Lys Pro Lys Arg Arg Asp
                 200                 205                 210

 Pro Gly Pro Thr Thr Asp Pro Leu Asp Pro Lys Gly Gln Gly Ala
                 215                 220                 225

 Ile Leu Ala Leu Ala Gly Asp Leu Ala Tyr Gln Thr Leu Pro Leu
                 230                 235                 240

 Arg Ala Leu Asp Val Gly Ser Gly Pro Leu Glu Asn Val Tyr Glu
                 245                 250                 255

 Ser Ile Arg Glu Leu Gly Asp Pro Ala Gly Arg Ser Ser Thr Cys
                 260                 265                 270

 Gly Ala Gly Thr Pro Pro Ala Ser Ser Cys Pro Ser Leu Gly Arg
                 275                 280                 285

 Gly Trp Arg Pro Leu Pro Ala Ser Leu Pro
                 290                 295

<210> 6136
<211> 723
<212> DNA
<213> Homo sapien

<400> 6136
 atggccgggc ctccgaggct cctgctgctg cccctgcttc tggcgctggc 50

 tcgcggcctg cctggggccc tggctgccca agaggtgcag cagtctcccc 100

 actgcacgac tgtccccgtg ggagcctccg tcaacatcac ctgctccacc 150

 agcgggggcc tgcgtgggat ctacctgagg cagctcgggc cacagcccca 200

 agacatcatt tactacgagg acggggtggt gcccactacg gacagacggt 250

 tccggggccg catcgacttc tcagggtccc aggacaacct gactatcacc 300

 atgcaccgcc tgcagctgtc ggacactggc acctacacct gccaggccat 350

 cacggaggtc aatgtctacg gctccggcac cctggtcctg gtgacagagg 400

 aacagtccca aggatggcac agatgctcgg acgccccacc aagggcctct 450

 gccctccctg ccccaccgac aggctccgcc ctccctgacc cgcagacagc 500

 ctctgccctc cctgacccgc cagcagcctc tgccctccct gcggccctgg 550

 cggtgatctc cttcctcctc gggctgggcc tgggggtggc gtgtgtgctg 600

 gcgaggacac agataaagaa actgtgctcg tggcgggata agaattcggc 650

 ggcatgtgtg gtgtacgagg acatgtcgca cagccgctgc aacacgctgt 700

 cctcccccaa ccagtaccag tga 723

<210> 6137
<211> 240
<212> PRT
<213> Homo sapien

<400> 6137
 Met Ala Gly Pro Pro Arg Leu Leu Leu Leu Pro Leu Leu Leu Ala
   1               5                  10                  15

 Leu Ala Arg Gly Leu Pro Gly Ala Leu Ala Ala Gln Glu Val Gln
                  20                  25                  30

 Gln Ser Pro His Cys Thr Thr Val Pro Val Gly Ala Ser Val Asn
                  35                  40                  45

 Ile Thr Cys Ser Thr Ser Gly Gly Leu Arg Gly Ile Tyr Leu Arg
                  50                  55                  60

 Gln Leu Gly Pro Gln Pro Gln Asp Ile Ile Tyr Tyr Glu Asp Gly
                  65                  70                  75

 Val Val Pro Thr Thr Asp Arg Arg Phe Arg Gly Arg Ile Asp Phe
                  80                  85                  90

 Ser Gly Ser Gln Asp Asn Leu Thr Ile Thr Met His Arg Leu Gln
                  95                 100                 105

 Leu Ser Asp Thr Gly Thr Tyr Thr Cys Gln Ala Ile Thr Glu Val
                 110                 115                 120

 Asn Val Tyr Gly Ser Gly Thr Leu Val Leu Val Thr Glu Glu Gln
                 125                 130                 135

 Ser Gln Gly Trp His Arg Cys Ser Asp Ala Pro Pro Arg Ala Ser
                 140                 145                 150

 Ala Leu Pro Ala Pro Pro Thr Gly Ser Ala Leu Pro Asp Pro Gln
                 155                 160                 165

 Thr Ala Ser Ala Leu Pro Asp Pro Pro Ala Ala Ser Ala Leu Pro
                 170                 175                 180

 Ala Ala Leu Ala Val Ile Ser Phe Leu Leu Gly Leu Gly Leu Gly
                 185                 190                 195

 Val Ala Cys Val Leu Ala Arg Thr Gln Ile Lys Lys Leu Cys Ser
                 200                 205                 210

 Trp Arg Asp Lys Asn Ser Ala Ala Cys Val Val Tyr Glu Asp Met
                 215                 220                 225

 Ser His Ser Arg Cys Asn Thr Leu Ser Ser Pro Asn Gln Tyr Gln
                 230                 235                 240

<210> 6138
<211> 2681
<212> DNA
<213> Homo sapien

<400> 6138
 cggccgcgtc ctcaagccgg cacctgagcg gcggagacgg ctgtagcaca 50

 aggatctgca tctccaatgg atactgaggg gtttggtgag ctccttcagc 100

 aagctgaaca gcttgctgct gagactgagg gcatctcaga gcttccccat 150

 gtggaacgga acttacagga gatccagcag gcgggagagc gcctgcgttc 200

 ccgtacccta acacgcacgt cccaggagac ggcagatgtc aaggcgtcag 250

 ttctcctcgg gtctcgggga cttgacatat cccacatctc ccagcgattg 300

 gagagtctga gtgcagccac cacctttgag cctcttgagc ctgtgaagga 350

 cactgacatt cagggcttcc tgaagaatga gaaggacaat gccctgctgt 400

 ctgccatcga agagtcccgg aagaggacct tcggcatggc tgaggagtac 450

 catcgggagt caatgttggt tgagtgggag caagtgaaac agcgaattct 500

 gcacacactg ctggcatcag gagaagacgc ccttgacttt actcaagaaa 550

 gcgagccaag ctacatcagt gatgtgggac cccctggtcg aagctctctg 600

 gataacatcg agatggccta tgcgcggcaa atttatatct ataatgagaa 650

 aattgtaaat ggacacctgc agcctaacct ggtggacctt tgtgcttccg 700

 tcgcagagct ggatgataag agcatttccg acatgtggac catggtaaaa 750

 caaatgacag acgtgttgtt gacaccggca acggatgccc tgaagaaccg 800

 cagcagcgtg gaagtgcgca tggagtttgt caggcaggcc ttggcgtacc 850

 ttgagcagag ttataagaat tacacccttg tgactgtctt tggaaatttg 900

 catcaggccc agctgggcgg ggtgcctggg acttaccaat tggttcgaag 950

 tttcctgaac attaaactgc cagctccctt gcctggacta caggatggag 1000

 aggtggaagg ccatcctgtg tgggcgctaa tttactactg catgcgctgt 1050

 ggagacctgc ttgccgcttc acaggtagtt aatcgagccc agcaccagct 1100

 gggagagttt aaaacctggt tccaggagta catgaacagc aaggacagaa 1150

 gattgtcccc agctacggaa aacaagctcc ggctgcatta ccgtagggcc 1200

 ctcaggaaca atacagatcc ctacaagcgg gccgtgtact gtatcattgg 1250

 cagatgtgac gtcaccgaca accagagtga agtggcggac aaaactgagg 1300

 attacctgtg gctgaagttg aaccaagtgt gttttgacga cgatggcacc 1350

 agctccccac aagacaggct cactctctca cagttccaga agcagttgtt 1400

 ggaagactat ggcgagtccc actttacggt gaaccagcaa cccttcctct 1450

 acttccaagt cctgttcctg acagcgcagt ttgaagcagc agttgccttt 1500

 cttttccgca tggagcggct gcgctgccat gctgtccatg tagcactggt 1550

 gctgtttgag ctgaagctgc ttttaaagtc ctctggacag agtgctcagc 1600

 tcctcagcca cgagcctggt gaccctcctt gcttgcggcg gctgaacttc 1650

 gtgcggctcc tcatgctgta cacccggaag tttgagtcca cggacccaag 1700

 ggaggccctc cagtacttct atttcctcag ggatgagaaa gatagtcaag 1750

 gagaaaacat gtttctgcgc tgtgtgagtg agcttgtgat tgaaagccga 1800

 gagttcgata tgattcttgg gaaactagag aatgacggaa gtagaaagcc 1850

 tggagtcata gataagttta ctagtgacac aaagcctatt atcaacaaag 1900

 ttgcttctgt ggcagaaaat aaaggactgt ttgaagaggc agcaaagctg 1950

 tatgaccttg ccaagaatgc tgacaaggta ctggagctga tgaacaaact 2000

 gctgagccct gtcgtccccc agatcagtgc cccgcaatcc aacaaggaga 2050

 ggctgaagaa catggcactc tccattgccg aacggtatag ggctcaagga 2100

 ataagcgcaa ataaatttgt ggactccacg ttctatcttc ttttggactt 2150

 gatcaccttt tttgacgagt atcatagtgg tcatattgat agagcttttg 2200

 atatcattga gcgcttgaag ctggtgcccc tgaatcagga aagtgtggaa 2250

 gagagagtgg ctgctttcag aaatttcagt gatgaaatca ggcacaacct 2300

 ctcagaagtg cttcttgcca ccatgaacat cttgttcaca cagtttaaga 2350

 ggctcaaggg gacaagtcca tcctcgtcat ccaggcccca gcgagtcatc 2400

 gaggaccgcg actctcaact ccgaagtcaa gcccgcactc tgattacctt 2450

 tgctggaatg ataccatacc gaacgtctgg ggacaccaat gcgaggctgg 2500

 tgcagatgga ggtcctcatg aattaagtgc catgctttgt gggagtctgg 2550

 gtcggcacac tgtcagtaca tcaggcacat gggcccacta ggctggggtt 2600

 tctggttttg tttctgttgt gttttgtttt ggtttctgta ttatgtattt 2650

 ttgtcaacgc caataaattt ctttgatttg t 2681

<210> 6139
<211> 819
<212> PRT
<213> Homo sapien

<400> 6139
 Met Asp Thr Glu Gly Phe Gly Glu Leu Leu Gln Gln Ala Glu Gln
   1               5                  10                  15

 Leu Ala Ala Glu Thr Glu Gly Ile Ser Glu Leu Pro His Val Glu
                  20                  25                  30

 Arg Asn Leu Gln Glu Ile Gln Gln Ala Gly Glu Arg Leu Arg Ser
                  35                  40                  45

 Arg Thr Leu Thr Arg Thr Ser Gln Glu Thr Ala Asp Val Lys Ala
                  50                  55                  60

 Ser Val Leu Leu Gly Ser Arg Gly Leu Asp Ile Ser His Ile Ser
                  65                  70                  75

 Gln Arg Leu Glu Ser Leu Ser Ala Ala Thr Thr Phe Glu Pro Leu
                  80                  85                  90

 Glu Pro Val Lys Asp Thr Asp Ile Gln Gly Phe Leu Lys Asn Glu
                  95                 100                 105

 Lys Asp Asn Ala Leu Leu Ser Ala Ile Glu Glu Ser Arg Lys Arg
                 110                 115                 120

 Thr Phe Gly Met Ala Glu Glu Tyr His Arg Glu Ser Met Leu Val
                 125                 130                 135

 Glu Trp Glu Gln Val Lys Gln Arg Ile Leu His Thr Leu Leu Ala
                 140                 145                 150

 Ser Gly Glu Asp Ala Leu Asp Phe Thr Gln Glu Ser Glu Pro Ser
                 155                 160                 165

 Tyr Ile Ser Asp Val Gly Pro Pro Gly Arg Ser Ser Leu Asp Asn
                 170                 175                 180

 Ile Glu Met Ala Tyr Ala Arg Gln Ile Tyr Ile Tyr Asn Glu Lys
                 185                 190                 195

 Ile Val Asn Gly His Leu Gln Pro Asn Leu Val Asp Leu Cys Ala
                 200                 205                 210

 Ser Val Ala Glu Leu Asp Asp Lys Ser Ile Ser Asp Met Trp Thr
                 215                 220                 225

 Met Val Lys Gln Met Thr Asp Val Leu Leu Thr Pro Ala Thr Asp
                 230                 235                 240

 Ala Leu Lys Asn Arg Ser Ser Val Glu Val Arg Met Glu Phe Val
                 245                 250                 255

 Arg Gln Ala Leu Ala Tyr Leu Glu Gln Ser Tyr Lys Asn Tyr Thr
                 260                 265                 270

 Leu Val Thr Val Phe Gly Asn Leu His Gln Ala Gln Leu Gly Gly
                 275                 280                 285

 Val Pro Gly Thr Tyr Gln Leu Val Arg Ser Phe Leu Asn Ile Lys
                 290                 295                 300

 Leu Pro Ala Pro Leu Pro Gly Leu Gln Asp Gly Glu Val Glu Gly
                 305                 310                 315

 His Pro Val Trp Ala Leu Ile Tyr Tyr Cys Met Arg Cys Gly Asp
                 320                 325                 330

 Leu Leu Ala Ala Ser Gln Val Val Asn Arg Ala Gln His Gln Leu
                 335                 340                 345

 Gly Glu Phe Lys Thr Trp Phe Gln Glu Tyr Met Asn Ser Lys Asp
                 350                 355                 360

 Arg Arg Leu Ser Pro Ala Thr Glu Asn Lys Leu Arg Leu His Tyr
                 365                 370                 375

 Arg Arg Ala Leu Arg Asn Asn Thr Asp Pro Tyr Lys Arg Ala Val
                 380                 385                 390

 Tyr Cys Ile Ile Gly Arg Cys Asp Val Thr Asp Asn Gln Ser Glu
                 395                 400                 405

 Val Ala Asp Lys Thr Glu Asp Tyr Leu Trp Leu Lys Leu Asn Gln
                 410                 415                 420

 Val Cys Phe Asp Asp Asp Gly Thr Ser Ser Pro Gln Asp Arg Leu
                 425                 430                 435

 Thr Leu Ser Gln Phe Gln Lys Gln Leu Leu Glu Asp Tyr Gly Glu
                 440                 445                 450

 Ser His Phe Thr Val Asn Gln Gln Pro Phe Leu Tyr Phe Gln Val
                 455                 460                 465

 Leu Phe Leu Thr Ala Gln Phe Glu Ala Ala Val Ala Phe Leu Phe
                 470                 475                 480

 Arg Met Glu Arg Leu Arg Cys His Ala Val His Val Ala Leu Val
                 485                 490                 495

 Leu Phe Glu Leu Lys Leu Leu Leu Lys Ser Ser Gly Gln Ser Ala
                 500                 505                 510

 Gln Leu Leu Ser His Glu Pro Gly Asp Pro Pro Cys Leu Arg Arg
                 515                 520                 525

 Leu Asn Phe Val Arg Leu Leu Met Leu Tyr Thr Arg Lys Phe Glu
                 530                 535                 540

 Ser Thr Asp Pro Arg Glu Ala Leu Gln Tyr Phe Tyr Phe Leu Arg
                 545                 550                 555

 Asp Glu Lys Asp Ser Gln Gly Glu Asn Met Phe Leu Arg Cys Val
                 560                 565                 570

 Ser Glu Leu Val Ile Glu Ser Arg Glu Phe Asp Met Ile Leu Gly
                 575                 580                 585

 Lys Leu Glu Asn Asp Gly Ser Arg Lys Pro Gly Val Ile Asp Lys
                 590                 595                 600

 Phe Thr Ser Asp Thr Lys Pro Ile Ile Asn Lys Val Ala Ser Val
                 605                 610                 615

 Ala Glu Asn Lys Gly Leu Phe Glu Glu Ala Ala Lys Leu Tyr Asp
                 620                 625                 630

 Leu Ala Lys Asn Ala Asp Lys Val Leu Glu Leu Met Asn Lys Leu
                 635                 640                 645

 Leu Ser Pro Val Val Pro Gln Ile Ser Ala Pro Gln Ser Asn Lys
                 650                 655                 660

 Glu Arg Leu Lys Asn Met Ala Leu Ser Ile Ala Glu Arg Tyr Arg
                 665                 670                 675

 Ala Gln Gly Ile Ser Ala Asn Lys Phe Val Asp Ser Thr Phe Tyr
                 680                 685                 690

 Leu Leu Leu Asp Leu Ile Thr Phe Phe Asp Glu Tyr His Ser Gly
                 695                 700                 705

 His Ile Asp Arg Ala Phe Asp Ile Ile Glu Arg Leu Lys Leu Val
                 710                 715                 720

 Pro Leu Asn Gln Glu Ser Val Glu Glu Arg Val Ala Ala Phe Arg
                 725                 730                 735

 Asn Phe Ser Asp Glu Ile Arg His Asn Leu Ser Glu Val Leu Leu
                 740                 745                 750

 Ala Thr Met Asn Ile Leu Phe Thr Gln Phe Lys Arg Leu Lys Gly
                 755                 760                 765

 Thr Ser Pro Ser Ser Ser Ser Arg Pro Gln Arg Val Ile Glu Asp
                 770                 775                 780

 Arg Asp Ser Gln Leu Arg Ser Gln Ala Arg Thr Leu Ile Thr Phe
                 785                 790                 795

 Ala Gly Met Ile Pro Tyr Arg Thr Ser Gly Asp Thr Asn Ala Arg
                 800                 805                 810

 Leu Val Gln Met Glu Val Leu Met Asn
                 815

<210> 6140
<211> 1209
<212> DNA
<213> Homo sapien

<400> 6140
 cagggctggg cggcggcggc ggcggcggtc atggaacgcc aagaggagtc 50

 tctgtccgcg cggccggccc tggagaccga ggggctgcgc ttcctgcaca 100

 ccacggtggg ctccctgctg gccacctatg gctggtacat cgtcttcagc 150

 tgcatccttc tctacgtggt ctttcagaag ctttccgccc ggctaagagc 200

 cttgaggcag aggcagctgg accgagctgc ggctgctgtg gaacctgatg 250

 ttgttgttaa acgacaagaa gctttagcag ctgctcgact gaaaatgcaa 300

 gaagaactaa atgcgcaagt tgaaaagcat aaggaaaaac tgaaacaact 350

 tgaagaagaa aaaaggagac agaagattga aatgtgggac agcatgcaag 400

 aaggaaaaag ttacaaagga aatgcaaaga agccccagga ggaagacagt 450

 cctgggcctt ccacttcatc tgtcctgaaa cggaaatcgg acagaaagcc 500

 tttgcgggga ggaggttata acccgttgtc tggtgaagga ggcggacttg 550

 ctcctggaga cctggacgca gaggcccgtc atctggcgga tgaggctaag 600

 aatcttgtta gtgtcacttt tgacattagc aagatgaacc cttaaccctc 650

 gattcaattg ccttacgcac gcttttcaca gtgactagcc aaggggaggt 700

 ggggttgatt tctgttccta actacacctg catatgtcag ggctccagtc 750

 agcaaaaggt atagatgttg cctctaggca tgaggtcatt ggtcacattc 800

 tacttggaga cagtgattgc attcattgat ttcatggtta attgctagtt 850

 ggtaggtaaa ggcctctaga tgattagcaa tcttgataaa agaggcctag 900

 taatgttctt ttgaggttag aaatccttgc tgctaggaca gtctctgtga 950

 caggttgcgt tgaatgatgt cttccttatc aatggtgagc ccaccagtga 1000

 ggattactga tgtggacagt tgatggggtt tgtttctgta tatttatttt 1050

 tatgtacaga actttgtaaa aacgaaacta tttaaaaaac aagaataaca 1100

 tttttagcat ctttattcaa ggagatttat ggacttcaat ttgtctatca 1150

 aacattaaat agctttttat tacaacctcc aaaaaaaaaa aaaaaaaaaa 1200

 aaaaaaaaa 1209

<210> 6141
<211> 204
<212> PRT
<213> Homo sapien

<400> 6141
 Met Glu Arg Gln Glu Glu Ser Leu Ser Ala Arg Pro Ala Leu Glu
   1               5                  10                  15

 Thr Glu Gly Leu Arg Phe Leu His Thr Thr Val Gly Ser Leu Leu
                  20                  25                  30

 Ala Thr Tyr Gly Trp Tyr Ile Val Phe Ser Cys Ile Leu Leu Tyr
                  35                  40                  45

 Val Val Phe Gln Lys Leu Ser Ala Arg Leu Arg Ala Leu Arg Gln
                  50                  55                  60

 Arg Gln Leu Asp Arg Ala Ala Ala Ala Val Glu Pro Asp Val Val
                  65                  70                  75

 Val Lys Arg Gln Glu Ala Leu Ala Ala Ala Arg Leu Lys Met Gln
                  80                  85                  90

 Glu Glu Leu Asn Ala Gln Val Glu Lys His Lys Glu Lys Leu Lys
                  95                 100                 105

 Gln Leu Glu Glu Glu Lys Arg Arg Gln Lys Ile Glu Met Trp Asp
                 110                 115                 120

 Ser Met Gln Glu Gly Lys Ser Tyr Lys Gly Asn Ala Lys Lys Pro
                 125                 130                 135

 Gln Glu Glu Asp Ser Pro Gly Pro Ser Thr Ser Ser Val Leu Lys
                 140                 145                 150

 Arg Lys Ser Asp Arg Lys Pro Leu Arg Gly Gly Gly Tyr Asn Pro
                 155                 160                 165

 Leu Ser Gly Glu Gly Gly Gly Leu Ala Pro Gly Asp Leu Asp Ala
                 170                 175                 180

 Glu Ala Arg His Leu Ala Asp Glu Ala Lys Asn Leu Val Ser Val
                 185                 190                 195

 Thr Phe Asp Ile Ser Lys Met Asn Pro
                 200

<210> 6142
<211> 10412
<212> DNA
<213> Homo sapien

<400> 6142
 gtaattgcga gcgagagtga gtggggccgg gacccgcaga gccgagccga 50

 cccttctctc ccgggctgcg gcagggcagg gcggggagct ccgcgcacca 100

 acagagccgg ttctcagggc gctttgctcc ttgttttttc cccggttctg 150

 ttttctcccc ttctccggaa ggcttgtcaa ggggtaggag aaagagacgc 200

 aaacacaaaa gtggaaaaca gttaatgacc agccacggcg tccctgctgt 250

 gagctctggc cgctgccttc cagggctccc gagccacacg ctgggggtgc 300

 tggctgaggg aacatggctt gttggcctca gctgaggttg ctgctgtgga 350

 agaacctcac tttcagaaga agacaaacat gtcagctgct gctggaagtg 400

 gcctggcctc tatttatctt cctgatcctg atctctgttc ggctgagcta 450

 cccaccctat gaacaacatg aatgccattt tccaaataaa gccatgccct 500

 ctgcaggaac acttccttgg gttcagggga ttatctgtaa tgccaacaac 550

 ccctgtttcc gttacccgac tcctggggag gctcccggag ttgttggaaa 600

 ctttaacaaa tccattgtgg ctcgcctgtt ctcagatgct cggaggcttc 650

 ttttatacag ccagaaagac accagcatga aggacatgcg caaagttctg 700

 agaacattac agcagatcaa gaaatccagc tcaaacttga agcttcaaga 750

 tttcctggtg gacaatgaaa ccttctctgg gttcctgtat cacaacctct 800

 ctctcccaaa gtctactgtg gacaagatgc tgagggctga tgtcattctc 850

 cacaaggtat ttttgcaagg ctaccagtta catttgacaa gtctgtgcaa 900

 tggatcaaaa tcagaagaga tgattcaact tggtgaccaa gaagtttctg 950

 agctttgtgg cctaccaagg gagaaactgg ctgcagcaga gcgagtactt 1000

 cgttccaaca tggacatcct gaagccaatc ctgagaacac taaactctac 1050

 atctcccttc ccgagcaagg agctggctga agccacaaaa acattgctgc 1100

 atagtcttgg gactctggcc caggagctgt tcagcatgag aagctggagt 1150

 gacatgcgac aggaggtgat gtttctgacc aatgtgaaca gctccagctc 1200

 ctccacccaa atctaccagg ctgtgtctcg tattgtctgc gggcatcccg 1250

 agggaggggg gctgaagatc aagtctctca actggtatga ggacaacaac 1300

 tacaaagccc tctttggagg caatggcact gaggaagatg ctgaaacctt 1350

 ctatgacaac tctacaactc cttactgcaa tgatttgatg aagaatttgg 1400

 agtctagtcc tctttcccgc attatctgga aagctctgaa gccgctgctc 1450

 gttgggaaga tcctgtatac acctgacact ccagccacaa ggcaggtcat 1500

 ggctgaggtg aacaagacct tccaggaact ggctgtgttc catgatctgg 1550

 aaggcatgtg ggaggaactc agccccaaga tctggacctt catggagaac 1600

 agccaagaaa tggaccttgt ccggatgctg ttggacagca gggacaatga 1650

 ccacttttgg gaacagcagt tggatggctt agattggaca gcccaagaca 1700

 tcgtggcgtt tttggccaag cacccagagg atgtccagtc cagtaatggt 1750

 tctgtgtaca cctggagaga agctttcaac gagactaacc aggcaatccg 1800

 gaccatatct cgcttcatgg agtgtgtcaa cctgaacaag ctagaaccca 1850

 tagcaacaga agtctggctc atcaacaagt ccatggagct gctggatgag 1900

 aggaagttct gggctggtat tgtgttcact ggaattactc caggcagcat 1950

 tgagctgccc catcatgtca agtacaagat ccgaatggac attgacaatg 2000

 tggagaggac aaataaaatc aaggatgggt actgggaccc tggtcctcga 2050

 gctgacccct ttgaggacat gcggtacgtc tgggggggct tcgcctactt 2100

 gcaggatgtg gtggagcagg caatcatcag ggtgctgacg ggcaccgaga 2150

 agaaaactgg tgtctatatg caacagatgc cctatccctg ttacgttgat 2200

 gacatctttc tgcgggtgat gagccggtca atgcccctct tcatgacgct 2250

 ggcctggatt tactcagtgg ctgtgatcat caagggcatc gtgtatgaga 2300

 aggaggcacg gctgaaagag accatgcgga tcatgggcct ggacaacagc 2350

 atcctctggt ttagctggtt cattagtagc ctcattcctc ttcttgtgag 2400

 cgctggcctg ctagtggtca tcctgaagtt aggaaacctg ctgccctaca 2450

 gtgatcccag cgtggtgttt gtcttcctgt ccgtgtttgc tgtggtgaca 2500

 atcctgcagt gcttcctgat tagcacactc ttctccagag ccaacctggc 2550

 agcagcctgt gggggcatca tctacttcac gctgtacctg ccctacgtcc 2600

 tgtgtgtggc atggcaggac tacgtgggct tcacactcaa gatcttcgct 2650

 agcctgctgt ctcctgtggc ttttgggttt ggctgtgagt actttgccct 2700

 ttttgaggag cagggcattg gagtgcagtg ggacaacctg tttgagagtc 2750

 ctgtggagga agatggcttc aatctcacca cttcggtctc catgatgctg 2800

 tttgacacct tcctctatgg ggtgatgacc tggtacattg aggctgtctt 2850

 tccaggccag tacggaattc ccaggccctg gtattttcct tgcaccaagt 2900

 cctactggtt tggcgaggaa agtgatgaga agagccaccc tggttccaac 2950

 cagaagagaa tatcagaaat ctgcatggag gaggaaccca cccacttgaa 3000

 gctgggcgtg tccattcaga acctggtaaa agtctaccga gatgggatga 3050

 aggtggctgt cgatggcctg gcactgaatt tttatgaggg ccagatcacc 3100

 tccttcctgg gccacaatgg agcggggaag acgaccacca tgtcaatcct 3150

 gaccgggttg ttccccccga cctcgggcac cgcctacatc ctgggaaaag 3200

 acattcgctc tgagatgagc accatccggc agaacctggg ggtctgtccc 3250

 cagcataacg tgctgtttga catgctgact gtcgaagaac acatctggtt 3300

 ctatgcccgc ttgaaagggc tctctgagaa gcacgtgaag gcggagatgg 3350

 agcagatggc cctggatgtt ggtttgccat caagcaagct gaaaagcaaa 3400

 acaagccagc tgtcaggtgg aatgcagaga aagctatctg tggccttggc 3450

 ctttgtcggg ggatctaagg ttgtcattct ggatgaaccc acagctggtg 3500

 tggaccctta ctcccgcagg ggaatatggg agctgctgct gaaataccga 3550

 caaggccgca ccattattct ctctacacac cacatggatg aagcggacgt 3600

 cctgggggac aggattgcca tcatctccca tgggaagctg tgctgtgtgg 3650

 gctcctccct gtttctgaag aaccagctgg gaacaggcta ctacctgacc 3700

 ttggtcaaga aagatgtgga atcctccctc agttcctgca gaaacagtag 3750

 tagcactgtg tcatacctga aaaaggagga cagtgtttct cagagcagtt 3800

 ctgatgctgg cctgggcagc gaccatgaga gtgacacgct gaccatcgat 3850

 gtctctgcta tctccaacct catcaggaag catgtgtctg aagcccggct 3900

 ggtggaagac atagggcatg agctgaccta tgtgctgcca tatgaagctg 3950

 ctaaggaggg agcctttgtg gaactctttc atgagattga tgaccggctc 4000

 tcagacctgg gcatttctag ttatggcatc tcagagacga ccctggaaga 4050

 aatattcctc aaggtggccg aagagagtgg ggtggatgct gagacctcag 4100

 atggtacctt gccagcaaga cgaaacaggc gggccttcgg ggacaagcag 4150

 agctgtcttc gcccgttcac tgaagatgat gctgctgatc caaatgattc 4200

 tgacatagac ccagaatcca gagagacaga cttgctcagt gggatggatg 4250

 gcaaagggtc ctaccaggtg aaaggctgga aacttacaca gcaacagttt 4300

 gtggcccttt tgtggaagag actgctaatt gccagacgga gtcggaaagg 4350

 attttttgct cagattgtct tgccagctgt gtttgtctgc attgcccttg 4400

 tgttcagcct gatcgtgcca ccctttggca agtaccccag cctggaactt 4450

 cagccctgga tgtacaacga acagtacaca tttgtcagca atgatgctcc 4500

 tgaggacacg ggaaccctgg aactcttaaa cgccctcacc aaagaccctg 4550

 gcttcgggac ccgctgtatg gaaggaaacc caatcccaga cacgccctgc 4600

 caggcagggg aggaagagtg gaccactgcc ccagttcccc agaccatcat 4650

 ggacctcttc cagaatggga actggacaat gcagaaccct tcacctgcat 4700

 gccagtgtag cagcgacaaa atcaagaaga tgctgcctgt gtgtccccca 4750

 ggggcagggg ggctgcctcc tccacaaaga aaacaaaaca ctgcagatat 4800

 ccttcaggac ctgacaggaa gaaacatttc ggattatctg gtgaagacgt 4850

 atgtgcagat catagccaaa agcttaaaga acaagatctg ggtgaatgag 4900

 tttaggtatg gcggcttttc cctgggtgtc agtaatactc aagcacttcc 4950

 tccgagtcaa gaagttaatg atgccatcaa acaaatgaag aaacacctaa 5000

 agctggccaa ggacagttct gcagatcgat ttctcaacag cttgggaaga 5050

 tttatgacag gactggacac caaaaataat gtcaaggtgt ggttcaataa 5100

 caagggctgg catgcaatca gctctttcct gaatgtcatc aacaatgcca 5150

 ttctccgggc caacctgcaa aagggagaga accctagcca ttatggaatt 5200

 actgctttca atcatcccct gaatctcacc aagcagcagc tctcagaggt 5250

 ggctctgatg accacatcag tggatgtcct tgtgtccatc tgtgtcatct 5300

 ttgcaatgtc cttcgtccca gccagctttg tcgtattcct gatccaggag 5350

 cgggtcagca aagcaaaaca cctgcagttc atcagtggag tgaagcctgt 5400

 catctactgg ctctctaatt ttgtctggga tatgtgcaat tacgttgtcc 5450

 ctgccacact ggtcattatc atcttcatct gcttccagca gaagtcctat 5500

 gtgtcctcca ccaatctgcc tgtgctagcc cttctacttt tgctgtatgg 5550

 gtggtcaatc acacctctca tgtacccagc ctcctttgtg ttcaagatcc 5600

 ccagcacagc ctatgtggtg ctcaccagcg tgaacctctt cattggcatt 5650

 aatggcagcg tggccacctt tgtgctggag ctgttcaccg acaataagct 5700

 gaataatatc aatgatatcc tgaagtccgt gttcttgatc ttcccacatt 5750

 tttgcctggg acgagggctc atcgacatgg tgaaaaacca ggcaatggct 5800

 gatgccctgg aaaggtttgg ggagaatcgc tttgtgtcac cattatcttg 5850

 ggacttggtg ggacgaaacc tcttcgccat ggccgtggaa ggggtggtgt 5900

 tcttcctcat tactgttctg atccagtaca gattcttcat caggcccaga 5950

 cctgtaaatg caaagctatc tcctctgaat gatgaagatg aagatgtgag 6000

 gcgggaaaga cagagaattc ttgatggtgg aggccagaat gacatcttag 6050

 aaatcaagga gttgacgaag atatatagaa ggaagcggaa gcctgctgtt 6100

 gacaggattt gcgtgggcat tcctcctggt gagtgctttg ggctcctggg 6150

 agttaatggg gctggaaaat catcaacttt caagatgtta acaggagata 6200

 ccactgttac cagaggagat gctttcctta acaaaaatag tatcttatca 6250

 aacatccatg aagtacatca gaacatgggc tactgccctc agtttgatgc 6300

 catcacagag ctgttgactg ggagagaaca cgtggagttc tttgcccttt 6350

 tgagaggagt cccagagaaa gaagttggca aggttggtga gtgggcgatt 6400

 cggaaactgg gcctcgtgaa gtatggagaa aaatatgctg gtaactatag 6450

 tggaggcaac aaacgcaagc tctctacagc catggctttg atcggcgggc 6500

 ctcctgtggt gtttctggat gaacccacca caggcatgga tcccaaagcc 6550

 cggcggttct tgtggaattg tgccctaagt gttgtcaagg aggggagatc 6600

 agtagtgctt acatctcata gtatggaaga atgtgaagct ctttgcacta 6650

 ggatggcaat catggtcaat ggaaggttca ggtgccttgg cagtgtccag 6700

 catctaaaaa ataggtttgg agatggttat acaatagttg tacgaatagc 6750

 agggtccaac ccggacctga agcctgtcca ggatttcttt ggacttgcat 6800

 ttcctggaag tgttctaaaa gagaaacacc ggaacatgct acaataccag 6850

 cttccatctt cattatcttc tctggccagg atattcagca tcctctccca 6900

 gagcaaaaag cgactccaca tagaagacta ctctgtttct cagacaacac 6950

 ttgaccaagt atttgtgaac tttgccaagg accaaagtga tgatgaccac 7000

 ttaaaagacc tctcattaca caaaaaccag acagtagtgg acgttgcagt 7050

 tctcacatct tttctacagg atgagaaagt gaaagaaagc tatgtatgaa 7100

 gaatcctgtt catacggggt ggctgaaagt aaagaggaac tagactttcc 7150

 tttgcaccat gtgaagtgtt gtggagaaaa gagccagaag ttgatgtggg 7200

 aagaagtaaa ctggatactg tactgatact attcaatgca atgcaattca 7250

 atgcaatgaa aacaaaattc cattacaggg gcagtgcctt tgtagcctat 7300

 gtcttgtatg gctctcaagt gaaagacttg aatttagttt tttacctata 7350

 cctatgtgaa actctattat ggaacccaat ggacatatgg gtttgaactc 7400

 acactttttt tttttttttt gttcctgtgt attctcattg gggttgcaac 7450

 aataattcat caagtaatca tggccagcga ttattgatca aaatcaaaag 7500

 gtaatgcaca tcctcattca ctaagccatg ccatgcccag gagactggtt 7550

 tcccggtgac acatccattg ctggcaatga gtgtgccaga gttattagtg 7600

 ccaagttttt cagaaagttt gaagcaccat ggtgtgtcat gctcactttt 7650

 gtgaaagctg ctctgctcag agtctatcaa cattgaatat cagttgacag 7700

 aatggtgcca tgcgtggcta acatcctgct ttgattccct ctgataagct 7750

 gttctggtgg cagtaacatg caacaaaaat gtgggtgtct ccaggcacgg 7800

 gaaacttggt tccattgtta tattgtccta tgcttcgagc catgggtcta 7850

 cagggtcatc cttatgagac tcttaaatat acttagatcc tggtaagagg 7900

 caaagaatca acagccaaac tgctggggct gcaagctgct gaagccaggg 7950

 catgggatta aagagattgt gcgttcaaac ctagggaagc ctgtgcccat 8000

 ttgtcctgac tgtctgctaa catggtacac tgcatctcaa gatgtttatc 8050

 tgacacaagt gtattatttc tggctttttg aattaatcta gaaaatgaaa 8100

 agatggagtt gtattttgac aaaaatgttt gtacttttta atgttatttg 8150

 gaattttaag ttctatcagt gacttctgaa tccttagaat ggcctctttg 8200

 tagaaccctg tggtatagag gagtatggcc actgccccac tatttttatt 8250

 ttcttatgta agtttgcata tcagtcatga ctagtgccta gaaagcaatg 8300

 tgatggtcag gatctcatga cattatattt gagtttcttt cagatcattt 8350

 aggatactct taatctcact tcatcaatca aatatttttt gagtgtatgc 8400

 tgtagctgaa agagtatgta cgtacgtata agactagaga gatattaagt 8450

 ctcagtacac ttcctgtgcc atgttattca gctcactggt ttacaaatat 8500

 aggttgtctt gtggttgtag gagcccactg taacaatact gggcagcctt 8550

 tttttttttt tttttaattg caacaatgca aaagccaaga aagtataagg 8600

 gtcacaagtc taaacaatga attcttcaac agggaaaaca gctagcttga 8650

 aaacttgctg aaaaacacaa cttgtgttta tggcatttag taccttcaaa 8700

 taattggctt tgcagatatt ggatacccca ttaaatctga cagtctcaaa 8750

 tttttcatct cttcaatcac tagtcaagaa aaatataaaa acaacaaata 8800

 cttccatatg gagcattttt cagagttttc taacccagtc ttatttttct 8850

 agtcagtaaa catttgtaaa aatactgttt cactaatact tactgttaac 8900

 tgtcttgaga gaaaagaaaa atatgagaga actattgttt ggggaagttc 8950

 aagtgatctt tcaatatcat tactaacttc ttccactttt tccagaattt 9000

 gaatattaac gctaaaggtg taagacttca gatttcaaat taatctttct 9050

 atatttttta aatttacaga atattatata acccactgct gaaaaagaaa 9100

 aaaatgattg ttttagaagt taaagtcaat attgatttta aatataagta 9150

 atgaaggcat atttccaata actagtgata tggcatcgtt gcattttaca 9200

 gtatcttcaa aaatacagaa tttatagaat aatttctcct catttaatat 9250

 ttttcaaaat caaagttatg gtttcctcat tttactaaaa tcgtattcta 9300

 attcttcatt atagtaaatc tatgagcaac tccttacttc ggttcctctg 9350

 atttcaaggc catattttaa aaaatcaaaa ggcactgtga actattttga 9400

 agaaaacaca acattttaat acagattgaa aggacctctt ctgaagctag 9450

 aaacaatcta tagttataca tcttcattaa tactgtgtta ccttttaaaa 9500

 tagtaatttt ttacattttc ctgtgtaaac ctaattgtgg tagaaatttt 9550

 taccaactct atactcaatc aagcaaaatt tctgtatatt ccctgtggaa 9600

 tgtacctatg tgagtttcag aaattctcaa aatacgtgtt caaaaatttc 9650

 tgcttttgca tctttgggac acctcagaaa acttattaac aactgtgaat 9700

 atgagaaata cagaagaaaa taataagccc tctatacata aatgcccagc 9750

 acaattcatt gttaaaaaac aaccaaacct cacactactg tatttcatta 9800

 tctgtactga aagcaaatgc tttgtgacta ttaaatgttg cacatcattc 9850

 attcactgta tagtaatcat tgactaaagc catttgtctg tgttttcttc 9900

 ttgtggttgt atatatcagg taaaatattt tccaaagagc catgtgtcat 9950

 gtaatactga accactttga tattgagaca ttaatttgta cccttgttat 10000

 tatctactag taataatgta atactgtaga aatattgctc taattctttt 10050

 caaaattgtt gcatccccct tagaatgttt ctatttccat aaggatttag 10100

 gtatgctatt atcccttctt ataccctaag atgaagctgt ttttgtgctc 10150

 tttgttcatc attggccctc attccaagca ctttacgctg tctgtaatgg 10200

 gatctatttt tgcactggaa tatctgagaa ttgcaaaact agacaaaagt 10250

 ttcacaacag atttctaagt taaatcattt tcattaaaag gaaaaaagaa 10300

 aaaaaatttt gtatgtcaat aactttatat gaagtattaa aatgcatatt 10350

 tctatgttgt aatataatga gtcacaaaat aaagctgtga cagttctgtt 10400

 ggtctacaga aa 10412

<210> 6143
<211> 2261
<212> PRT
<213> Homo sapien

<400> 6143
 Met Ala Cys Trp Pro Gln Leu Arg Leu Leu Leu Trp Lys Asn Leu
   1               5                  10                  15

 Thr Phe Arg Arg Arg Gln Thr Cys Gln Leu Leu Leu Glu Val Ala
                  20                  25                  30

 Trp Pro Leu Phe Ile Phe Leu Ile Leu Ile Ser Val Arg Leu Ser
                  35                  40                  45

 Tyr Pro Pro Tyr Glu Gln His Glu Cys His Phe Pro Asn Lys Ala
                  50                  55                  60

 Met Pro Ser Ala Gly Thr Leu Pro Trp Val Gln Gly Ile Ile Cys
                  65                  70                  75

 Asn Ala Asn Asn Pro Cys Phe Arg Tyr Pro Thr Pro Gly Glu Ala
                  80                  85                  90

 Pro Gly Val Val Gly Asn Phe Asn Lys Ser Ile Val Ala Arg Leu
                  95                 100                 105

 Phe Ser Asp Ala Arg Arg Leu Leu Leu Tyr Ser Gln Lys Asp Thr
                 110                 115                 120

 Ser Met Lys Asp Met Arg Lys Val Leu Arg Thr Leu Gln Gln Ile
                 125                 130                 135

 Lys Lys Ser Ser Ser Asn Leu Lys Leu Gln Asp Phe Leu Val Asp
                 140                 145                 150

 Asn Glu Thr Phe Ser Gly Phe Leu Tyr His Asn Leu Ser Leu Pro
                 155                 160                 165

 Lys Ser Thr Val Asp Lys Met Leu Arg Ala Asp Val Ile Leu His
                 170                 175                 180

 Lys Val Phe Leu Gln Gly Tyr Gln Leu His Leu Thr Ser Leu Cys
                 185                 190                 195

 Asn Gly Ser Lys Ser Glu Glu Met Ile Gln Leu Gly Asp Gln Glu
                 200                 205                 210

 Val Ser Glu Leu Cys Gly Leu Pro Arg Glu Lys Leu Ala Ala Ala
                 215                 220                 225

 Glu Arg Val Leu Arg Ser Asn Met Asp Ile Leu Lys Pro Ile Leu
                 230                 235                 240

 Arg Thr Leu Asn Ser Thr Ser Pro Phe Pro Ser Lys Glu Leu Ala
                 245                 250                 255

 Glu Ala Thr Lys Thr Leu Leu His Ser Leu Gly Thr Leu Ala Gln
                 260                 265                 270

 Glu Leu Phe Ser Met Arg Ser Trp Ser Asp Met Arg Gln Glu Val
                 275                 280                 285

 Met Phe Leu Thr Asn Val Asn Ser Ser Ser Ser Ser Thr Gln Ile
                 290                 295                 300

 Tyr Gln Ala Val Ser Arg Ile Val Cys Gly His Pro Glu Gly Gly
                 305                 310                 315

 Gly Leu Lys Ile Lys Ser Leu Asn Trp Tyr Glu Asp Asn Asn Tyr
                 320                 325                 330

 Lys Ala Leu Phe Gly Gly Asn Gly Thr Glu Glu Asp Ala Glu Thr
                 335                 340                 345

 Phe Tyr Asp Asn Ser Thr Thr Pro Tyr Cys Asn Asp Leu Met Lys
                 350                 355                 360

 Asn Leu Glu Ser Ser Pro Leu Ser Arg Ile Ile Trp Lys Ala Leu
                 365                 370                 375

 Lys Pro Leu Leu Val Gly Lys Ile Leu Tyr Thr Pro Asp Thr Pro
                 380                 385                 390

 Ala Thr Arg Gln Val Met Ala Glu Val Asn Lys Thr Phe Gln Glu
                 395                 400                 405

 Leu Ala Val Phe His Asp Leu Glu Gly Met Trp Glu Glu Leu Ser
                 410                 415                 420

 Pro Lys Ile Trp Thr Phe Met Glu Asn Ser Gln Glu Met Asp Leu
                 425                 430                 435

 Val Arg Met Leu Leu Asp Ser Arg Asp Asn Asp His Phe Trp Glu
                 440                 445                 450

 Gln Gln Leu Asp Gly Leu Asp Trp Thr Ala Gln Asp Ile Val Ala
                 455                 460                 465

 Phe Leu Ala Lys His Pro Glu Asp Val Gln Ser Ser Asn Gly Ser
                 470                 475                 480

 Val Tyr Thr Trp Arg Glu Ala Phe Asn Glu Thr Asn Gln Ala Ile
                 485                 490                 495

 Arg Thr Ile Ser Arg Phe Met Glu Cys Val Asn Leu Asn Lys Leu
                 500                 505                 510

 Glu Pro Ile Ala Thr Glu Val Trp Leu Ile Asn Lys Ser Met Glu
                 515                 520                 525

 Leu Leu Asp Glu Arg Lys Phe Trp Ala Gly Ile Val Phe Thr Gly
                 530                 535                 540

 Ile Thr Pro Gly Ser Ile Glu Leu Pro His His Val Lys Tyr Lys
                 545                 550                 555

 Ile Arg Met Asp Ile Asp Asn Val Glu Arg Thr Asn Lys Ile Lys
                 560                 565                 570

 Asp Gly Tyr Trp Asp Pro Gly Pro Arg Ala Asp Pro Phe Glu Asp
                 575                 580                 585

 Met Arg Tyr Val Trp Gly Gly Phe Ala Tyr Leu Gln Asp Val Val
                 590                 595                 600

 Glu Gln Ala Ile Ile Arg Val Leu Thr Gly Thr Glu Lys Lys Thr
                 605                 610                 615

 Gly Val Tyr Met Gln Gln Met Pro Tyr Pro Cys Tyr Val Asp Asp
                 620                 625                 630

 Ile Phe Leu Arg Val Met Ser Arg Ser Met Pro Leu Phe Met Thr
                 635                 640                 645

 Leu Ala Trp Ile Tyr Ser Val Ala Val Ile Ile Lys Gly Ile Val
                 650                 655                 660

 Tyr Glu Lys Glu Ala Arg Leu Lys Glu Thr Met Arg Ile Met Gly
                 665                 670                 675

 Leu Asp Asn Ser Ile Leu Trp Phe Ser Trp Phe Ile Ser Ser Leu
                 680                 685                 690

 Ile Pro Leu Leu Val Ser Ala Gly Leu Leu Val Val Ile Leu Lys
                 695                 700                 705

 Leu Gly Asn Leu Leu Pro Tyr Ser Asp Pro Ser Val Val Phe Val
                 710                 715                 720

 Phe Leu Ser Val Phe Ala Val Val Thr Ile Leu Gln Cys Phe Leu
                 725                 730                 735

 Ile Ser Thr Leu Phe Ser Arg Ala Asn Leu Ala Ala Ala Cys Gly
                 740                 745                 750

 Gly Ile Ile Tyr Phe Thr Leu Tyr Leu Pro Tyr Val Leu Cys Val
                 755                 760                 765

 Ala Trp Gln Asp Tyr Val Gly Phe Thr Leu Lys Ile Phe Ala Ser
                 770                 775                 780

 Leu Leu Ser Pro Val Ala Phe Gly Phe Gly Cys Glu Tyr Phe Ala
                 785                 790                 795

 Leu Phe Glu Glu Gln Gly Ile Gly Val Gln Trp Asp Asn Leu Phe
                 800                 805                 810

 Glu Ser Pro Val Glu Glu Asp Gly Phe Asn Leu Thr Thr Ser Val
                 815                 820                 825

 Ser Met Met Leu Phe Asp Thr Phe Leu Tyr Gly Val Met Thr Trp
                 830                 835                 840

 Tyr Ile Glu Ala Val Phe Pro Gly Gln Tyr Gly Ile Pro Arg Pro
                 845                 850                 855

 Trp Tyr Phe Pro Cys Thr Lys Ser Tyr Trp Phe Gly Glu Glu Ser
                 860                 865                 870

 Asp Glu Lys Ser His Pro Gly Ser Asn Gln Lys Arg Ile Ser Glu
                 875                 880                 885

 Ile Cys Met Glu Glu Glu Pro Thr His Leu Lys Leu Gly Val Ser
                 890                 895                 900

 Ile Gln Asn Leu Val Lys Val Tyr Arg Asp Gly Met Lys Val Ala
                 905                 910                 915

 Val Asp Gly Leu Ala Leu Asn Phe Tyr Glu Gly Gln Ile Thr Ser
                 920                 925                 930

 Phe Leu Gly His Asn Gly Ala Gly Lys Thr Thr Thr Met Ser Ile
                 935                 940                 945

 Leu Thr Gly Leu Phe Pro Pro Thr Ser Gly Thr Ala Tyr Ile Leu
                 950                 955                 960

 Gly Lys Asp Ile Arg Ser Glu Met Ser Thr Ile Arg Gln Asn Leu
                 965                 970                 975

 Gly Val Cys Pro Gln His Asn Val Leu Phe Asp Met Leu Thr Val
                 980                 985                 990

 Glu Glu His Ile Trp Phe Tyr Ala Arg Leu Lys Gly Leu Ser Glu
                 995                1000                1005

 Lys His Val Lys Ala Glu Met Glu Gln Met Ala Leu Asp Val Gly
                1010                1015                1020

 Leu Pro Ser Ser Lys Leu Lys Ser Lys Thr Ser Gln Leu Ser Gly
                1025                1030                1035

 Gly Met Gln Arg Lys Leu Ser Val Ala Leu Ala Phe Val Gly Gly
                1040                1045                1050

 Ser Lys Val Val Ile Leu Asp Glu Pro Thr Ala Gly Val Asp Pro
                1055                1060                1065

 Tyr Ser Arg Arg Gly Ile Trp Glu Leu Leu Leu Lys Tyr Arg Gln
                1070                1075                1080

 Gly Arg Thr Ile Ile Leu Ser Thr His His Met Asp Glu Ala Asp
                1085                1090                1095

 Val Leu Gly Asp Arg Ile Ala Ile Ile Ser His Gly Lys Leu Cys
                1100                1105                1110

 Cys Val Gly Ser Ser Leu Phe Leu Lys Asn Gln Leu Gly Thr Gly
                1115                1120                1125

 Tyr Tyr Leu Thr Leu Val Lys Lys Asp Val Glu Ser Ser Leu Ser
                1130                1135                1140

 Ser Cys Arg Asn Ser Ser Ser Thr Val Ser Tyr Leu Lys Lys Glu
                1145                1150                1155

 Asp Ser Val Ser Gln Ser Ser Ser Asp Ala Gly Leu Gly Ser Asp
                1160                1165                1170

 His Glu Ser Asp Thr Leu Thr Ile Asp Val Ser Ala Ile Ser Asn
                1175                1180                1185

 Leu Ile Arg Lys His Val Ser Glu Ala Arg Leu Val Glu Asp Ile
                1190                1195                1200

 Gly His Glu Leu Thr Tyr Val Leu Pro Tyr Glu Ala Ala Lys Glu
                1205                1210                1215

 Gly Ala Phe Val Glu Leu Phe His Glu Ile Asp Asp Arg Leu Ser
                1220                1225                1230

 Asp Leu Gly Ile Ser Ser Tyr Gly Ile Ser Glu Thr Thr Leu Glu
                1235                1240                1245

 Glu Ile Phe Leu Lys Val Ala Glu Glu Ser Gly Val Asp Ala Glu
                1250                1255                1260

 Thr Ser Asp Gly Thr Leu Pro Ala Arg Arg Asn Arg Arg Ala Phe
                1265                1270                1275

 Gly Asp Lys Gln Ser Cys Leu Arg Pro Phe Thr Glu Asp Asp Ala
                1280                1285                1290

 Ala Asp Pro Asn Asp Ser Asp Ile Asp Pro Glu Ser Arg Glu Thr
                1295                1300                1305

 Asp Leu Leu Ser Gly Met Asp Gly Lys Gly Ser Tyr Gln Val Lys
                1310                1315                1320

 Gly Trp Lys Leu Thr Gln Gln Gln Phe Val Ala Leu Leu Trp Lys
                1325                1330                1335

 Arg Leu Leu Ile Ala Arg Arg Ser Arg Lys Gly Phe Phe Ala Gln
                1340                1345                1350

 Ile Val Leu Pro Ala Val Phe Val Cys Ile Ala Leu Val Phe Ser
                1355                1360                1365

 Leu Ile Val Pro Pro Phe Gly Lys Tyr Pro Ser Leu Glu Leu Gln
                1370                1375                1380

 Pro Trp Met Tyr Asn Glu Gln Tyr Thr Phe Val Ser Asn Asp Ala
                1385                1390                1395

 Pro Glu Asp Thr Gly Thr Leu Glu Leu Leu Asn Ala Leu Thr Lys
                1400                1405                1410

 Asp Pro Gly Phe Gly Thr Arg Cys Met Glu Gly Asn Pro Ile Pro
                1415                1420                1425

 Asp Thr Pro Cys Gln Ala Gly Glu Glu Glu Trp Thr Thr Ala Pro
                1430                1435                1440

 Val Pro Gln Thr Ile Met Asp Leu Phe Gln Asn Gly Asn Trp Thr
                1445                1450                1455

 Met Gln Asn Pro Ser Pro Ala Cys Gln Cys Ser Ser Asp Lys Ile
                1460                1465                1470

 Lys Lys Met Leu Pro Val Cys Pro Pro Gly Ala Gly Gly Leu Pro
                1475                1480                1485

 Pro Pro Gln Arg Lys Gln Asn Thr Ala Asp Ile Leu Gln Asp Leu
                1490                1495                1500

 Thr Gly Arg Asn Ile Ser Asp Tyr Leu Val Lys Thr Tyr Val Gln
                1505                1510                1515

 Ile Ile Ala Lys Ser Leu Lys Asn Lys Ile Trp Val Asn Glu Phe
                1520                1525                1530

 Arg Tyr Gly Gly Phe Ser Leu Gly Val Ser Asn Thr Gln Ala Leu
                1535                1540                1545

 Pro Pro Ser Gln Glu Val Asn Asp Ala Ile Lys Gln Met Lys Lys
                1550                1555                1560

 His Leu Lys Leu Ala Lys Asp Ser Ser Ala Asp Arg Phe Leu Asn
                1565                1570                1575

 Ser Leu Gly Arg Phe Met Thr Gly Leu Asp Thr Lys Asn Asn Val
                1580                1585                1590

 Lys Val Trp Phe Asn Asn Lys Gly Trp His Ala Ile Ser Ser Phe
                1595                1600                1605

 Leu Asn Val Ile Asn Asn Ala Ile Leu Arg Ala Asn Leu Gln Lys
                1610                1615                1620

 Gly Glu Asn Pro Ser His Tyr Gly Ile Thr Ala Phe Asn His Pro
                1625                1630                1635

 Leu Asn Leu Thr Lys Gln Gln Leu Ser Glu Val Ala Leu Met Thr
                1640                1645                1650

 Thr Ser Val Asp Val Leu Val Ser Ile Cys Val Ile Phe Ala Met
                1655                1660                1665

 Ser Phe Val Pro Ala Ser Phe Val Val Phe Leu Ile Gln Glu Arg
                1670                1675                1680

 Val Ser Lys Ala Lys His Leu Gln Phe Ile Ser Gly Val Lys Pro
                1685                1690                1695

 Val Ile Tyr Trp Leu Ser Asn Phe Val Trp Asp Met Cys Asn Tyr
                1700                1705                1710

 Val Val Pro Ala Thr Leu Val Ile Ile Ile Phe Ile Cys Phe Gln
                1715                1720                1725

 Gln Lys Ser Tyr Val Ser Ser Thr Asn Leu Pro Val Leu Ala Leu
                1730                1735                1740

 Leu Leu Leu Leu Tyr Gly Trp Ser Ile Thr Pro Leu Met Tyr Pro
                1745                1750                1755

 Ala Ser Phe Val Phe Lys Ile Pro Ser Thr Ala Tyr Val Val Leu
                1760                1765                1770

 Thr Ser Val Asn Leu Phe Ile Gly Ile Asn Gly Ser Val Ala Thr
                1775                1780                1785

 Phe Val Leu Glu Leu Phe Thr Asp Asn Lys Leu Asn Asn Ile Asn
                1790                1795                1800

 Asp Ile Leu Lys Ser Val Phe Leu Ile Phe Pro His Phe Cys Leu
                1805                1810                1815

 Gly Arg Gly Leu Ile Asp Met Val Lys Asn Gln Ala Met Ala Asp
                1820                1825                1830

 Ala Leu Glu Arg Phe Gly Glu Asn Arg Phe Val Ser Pro Leu Ser
                1835                1840                1845

 Trp Asp Leu Val Gly Arg Asn Leu Phe Ala Met Ala Val Glu Gly
                1850                1855                1860

 Val Val Phe Phe Leu Ile Thr Val Leu Ile Gln Tyr Arg Phe Phe
                1865                1870                1875

 Ile Arg Pro Arg Pro Val Asn Ala Lys Leu Ser Pro Leu Asn Asp
                1880                1885                1890

 Glu Asp Glu Asp Val Arg Arg Glu Arg Gln Arg Ile Leu Asp Gly
                1895                1900                1905

 Gly Gly Gln Asn Asp Ile Leu Glu Ile Lys Glu Leu Thr Lys Ile
                1910                1915                1920

 Tyr Arg Arg Lys Arg Lys Pro Ala Val Asp Arg Ile Cys Val Gly
                1925                1930                1935

 Ile Pro Pro Gly Glu Cys Phe Gly Leu Leu Gly Val Asn Gly Ala
                1940                1945                1950

 Gly Lys Ser Ser Thr Phe Lys Met Leu Thr Gly Asp Thr Thr Val
                1955                1960                1965

 Thr Arg Gly Asp Ala Phe Leu Asn Lys Asn Ser Ile Leu Ser Asn
                1970                1975                1980

 Ile His Glu Val His Gln Asn Met Gly Tyr Cys Pro Gln Phe Asp
                1985                1990                1995

 Ala Ile Thr Glu Leu Leu Thr Gly Arg Glu His Val Glu Phe Phe
                2000                2005                2010

 Ala Leu Leu Arg Gly Val Pro Glu Lys Glu Val Gly Lys Val Gly
                2015                2020                2025

 Glu Trp Ala Ile Arg Lys Leu Gly Leu Val Lys Tyr Gly Glu Lys
                2030                2035                2040

 Tyr Ala Gly Asn Tyr Ser Gly Gly Asn Lys Arg Lys Leu Ser Thr
                2045                2050                2055

 Ala Met Ala Leu Ile Gly Gly Pro Pro Val Val Phe Leu Asp Glu
                2060                2065                2070

 Pro Thr Thr Gly Met Asp Pro Lys Ala Arg Arg Phe Leu Trp Asn
                2075                2080                2085

 Cys Ala Leu Ser Val Val Lys Glu Gly Arg Ser Val Val Leu Thr
                2090                2095                2100

 Ser His Ser Met Glu Glu Cys Glu Ala Leu Cys Thr Arg Met Ala
                2105                2110                2115

 Ile Met Val Asn Gly Arg Phe Arg Cys Leu Gly Ser Val Gln His
                2120                2125                2130

 Leu Lys Asn Arg Phe Gly Asp Gly Tyr Thr Ile Val Val Arg Ile
                2135                2140                2145

 Ala Gly Ser Asn Pro Asp Leu Lys Pro Val Gln Asp Phe Phe Gly
                2150                2155                2160

 Leu Ala Phe Pro Gly Ser Val Leu Lys Glu Lys His Arg Asn Met
                2165                2170                2175

 Leu Gln Tyr Gln Leu Pro Ser Ser Leu Ser Ser Leu Ala Arg Ile
                2180                2185                2190

 Phe Ser Ile Leu Ser Gln Ser Lys Lys Arg Leu His Ile Glu Asp
                2195                2200                2205

 Tyr Ser Val Ser Gln Thr Thr Leu Asp Gln Val Phe Val Asn Phe
                2210                2215                2220

 Ala Lys Asp Gln Ser Asp Asp Asp His Leu Lys Asp Leu Ser Leu
                2225                2230                2235

 His Lys Asn Gln Thr Val Val Asp Val Ala Val Leu Thr Ser Phe
                2240                2245                2250

 Leu Gln Asp Glu Lys Val Lys Glu Ser Tyr Val
                2255                2260

<210> 6144
<211> 3697
<212> DNA
<213> Homo sapien

<400> 6144
 cccaagactg tccccgctgg aggcggtaga gggatccaga agtaatgaga 50

 tgctaatgag tcgcgaataa agcccgggcg gcgccccgcg cccctcgcgg 100

 aagcccacac tccgcgcgac tccaggcgca cgccccgggc cgccccgcat 150

 cccagcatcc ccgcccgatc tcggcgtttc cgcccccgcc cccgcccccg 200

 ccctcccacc cgctcagacc tggttgccag cccaacagga agcggcccct 250

 cccggcttcg gagccgccgc cactcgtctc tgcccagctg ctgccctccc 300

 caggaggcct ccatggcttc acctacctcc accaacccag cgcatgccca 350

 ctttgagagc ttcctgcagg cccagctgtg ccaggacgtg ctgagcagct 400

 tccaggagct gtgtggggcc ctggggctgg aacccggtgg ggggctgccc 450

 cagtaccaca agatcaagga ccagctcaac tactggagcg ccaagtcact 500

 gtggaccaag ctggacaagc gagcaggcca gcctgtctac cagcagggcc 550

 gggcctgcac cagcaccaag tgcctggtgg tgggtgctgg accttgcggg 600

 ctgcgggtcg ctgtggagct ggcgctgctg ggggcccgag tggtgctggt 650

 ggaaaagcgc accaagttct ctcgccacaa cgtgctccac ctctggccct 700

 tcaccatcca cgacctgcgg gcactcggtg ctaagaagtt ctacgggcgc 750

 ttctgcaccg gcaccctgga ccacatcagc atcaggcagc tccagctgct 800

 tctgctgaag gtagcattgc tgctgggggt ggaaattcac tggggtgtca 850

 ctttcactgg cctccagccc cctcctagga aggggagtgg ctggcgtgcc 900

 cagctccaac ccaacccccc tgcccagctg gccaactatg aatttgacgt 950

 ccttatctcg gctgcaggag gtaaattcgt ccctgaaggc ttcaaagttc 1000

 gagaaatgcg aggcaaactg gccattggca tcacagccaa ctttgtgaat 1050

 ggacgcaccg tggaggagac acaggtgccg gagatcagtg gtgtagccag 1100

 gatctacaac cagagcttct tccagagcct tctcaaagcc acaggcattg 1150

 atctggagaa cattgtgtac tacaaggacg acacccacta ctttgtgatg 1200

 acagccaaga agcagtgcct gctgcggctg ggggtgctgc gccaggactg 1250

 gccagacacc aatcggctgc tgggcagtgc caatgtggtg cccgaggctc 1300

 tgcagcgctt tacccgggca gctgctgact ttgccaccca tggcaagctc 1350

 gggaaactag agtttgccca ggatgcccat gggcagcctg atgtctctgc 1400

 ctttgacttc acgagcatga tgcgggcaga gagttctgct cgtgtgcaag 1450

 agaagcatgg cgcccgcctg ctgctgggac tggtggggga ctgcctggtg 1500

 gagcccttct ggcccctggg cactggagtg gcacggggct tcctggcagc 1550

 ctttgatgca gcctggatgg tgaagcggtg ggcagagggc gctgagtccc 1600

 tagaggtgtt ggctgagcgt gagagcctgt accagcttct gtcacagaca 1650

 tccccagaaa acatgcatcg caatgtggcc cagtatgggc tggacccagc 1700

 cacccgctac cccaacctga acctccgggc agtgaccccc aatcaggtac 1750

 gagacctgta tgatgtgcta gccaaggagc ctgtgcagag gaacaacgac 1800

 aagacagata cagggatgcc agccaccggg tcggcaggca cccaggagga 1850

 gctgctacgc tggtgccagg agcagacagc tgggtacccg ggagtccacg 1900

 tctccgattt gtcttcctcc tgggctgatg ggctagctct gtgtgccctg 1950

 gtgtaccggc tgcagcctgg cctgctggaa ccctcagagc tgcaggggct 2000

 gggagctctg gaagcaactg cttgggcact aaaggtggca gagaatgagc 2050

 tgggcatcac accggtggtg tctgcacagg ccgtggtagc agggagtgac 2100

 ccactgggcc tcattgccta cctcagccac ttccacagtg ccttcaagag 2150

 catggcccac agcccaggcc ctgtcagcca ggcctcccca gggacctcca 2200

 gtgctgtatt attccttagt aaacttcaga ggaccctgca gcgatcccgg 2250

 gccaaggaaa atgcagagga tgctggtggc aagaagctgc gcttggagat 2300

 ggaggccgag accccaagta ctgaggtgcc acctgaccca gagcctggtg 2350

 tacccctgac acccccatcc caacaccagg aggccggtgc tggggacctg 2400

 tgtgcacttt gtggggaaca cctctatgtc ctggaacgcc tctgtgtcaa 2450

 cggccatttc ttccaccgga gctgcttccg ctgccatacc tgtgaggcca 2500

 cactgtggcc aggtggctat gagcagcacc caggagatgg acatttctac 2550

 tgcctccagc acctgcccca gacagaccac aaaaaggaag gcagcgatag 2600

 aggccctgag agtccggagc tccccacacc aagtgagaat agcatgccac 2650

 caggcctctc aactcccaca gcctcgcagg agggggccgg tcctgttcca 2700

 gatcccagcc agcccacccg tcggcagatc cgcctctcca gcccggagcg 2750

 ccagcggttg tcctccctta accttacccc tgacccggaa atggagcctc 2800

 cacccaagcc tccccgcagc tgctccgcct tggcccgcca cgccctggag 2850

 agcagctttg tgggctgggg cctgccagtc cagagccctc aagctcttgt 2900

 ggccatggag aaggaggaaa aagagagtcc cttctccagt gaagaggaag 2950

 aagaagatgt gcctttggac tcagatgtgg aacaggccct gcagaccttt 3000

 gccaagacct caggcaccat gaataactac ccaacatggc gtcggactct 3050

 gctgcgccgt gcgaaggagg aggagatgaa gaggttctgc aaggcccaga 3100

 ccatccaacg gcgactaaat gagattgagg ctgccttgag ggagctagag 3150

 gccgagggcg tgaagctgga gctggccttg aggcgccaga gcagttcccc 3200

 agaacagcaa aagaaactat gggtaggaca gctgctacag ctcgttgaca 3250

 agaaaaacag cttggtggct gaggaggccg agctcatgat cacggtgcag 3300

 gaattgaatc tggaggagaa acagtggcag ctggaccagg agctacgagg 3350

 ctacatgaac cgggaagaaa acctaaagac agctgctgat cggcaggctg 3400

 aggaccaggt cctgaggaag ctggtggatt tggtcaacca gagagatgcc 3450

 ctcatccgct tccaggagga gcgcaggctc agcgagctgg ccttggggac 3500

 aggggcccag ggctagacga gggtgggccg tctgctttcg ttcccacaaa 3550

 gaaagcacct caccccagca cagtgccacc cctgttcatc tgggctgcct 3600

 ggcagagagc cttgctgttt acaattaaaa tgtttctgcc ccaaaaaaaa 3650

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 3697

<210> 6145
<211> 1067
<212> PRT
<213> Homo sapien

<400> 6145
 Met Ala Ser Pro Thr Ser Thr Asn Pro Ala His Ala His Phe Glu
   1               5                  10                  15

 Ser Phe Leu Gln Ala Gln Leu Cys Gln Asp Val Leu Ser Ser Phe
                  20                  25                  30

 Gln Glu Leu Cys Gly Ala Leu Gly Leu Glu Pro Gly Gly Gly Leu
                  35                  40                  45

 Pro Gln Tyr His Lys Ile Lys Asp Gln Leu Asn Tyr Trp Ser Ala
                  50                  55                  60

 Lys Ser Leu Trp Thr Lys Leu Asp Lys Arg Ala Gly Gln Pro Val
                  65                  70                  75

 Tyr Gln Gln Gly Arg Ala Cys Thr Ser Thr Lys Cys Leu Val Val
                  80                  85                  90

 Gly Ala Gly Pro Cys Gly Leu Arg Val Ala Val Glu Leu Ala Leu
                  95                 100                 105

 Leu Gly Ala Arg Val Val Leu Val Glu Lys Arg Thr Lys Phe Ser
                 110                 115                 120

 Arg His Asn Val Leu His Leu Trp Pro Phe Thr Ile His Asp Leu
                 125                 130                 135

 Arg Ala Leu Gly Ala Lys Lys Phe Tyr Gly Arg Phe Cys Thr Gly
                 140                 145                 150

 Thr Leu Asp His Ile Ser Ile Arg Gln Leu Gln Leu Leu Leu Leu
                 155                 160                 165

 Lys Val Ala Leu Leu Leu Gly Val Glu Ile His Trp Gly Val Thr
                 170                 175                 180

 Phe Thr Gly Leu Gln Pro Pro Pro Arg Lys Gly Ser Gly Trp Arg
                 185                 190                 195

 Ala Gln Leu Gln Pro Asn Pro Pro Ala Gln Leu Ala Asn Tyr Glu
                 200                 205                 210

 Phe Asp Val Leu Ile Ser Ala Ala Gly Gly Lys Phe Val Pro Glu
                 215                 220                 225

 Gly Phe Lys Val Arg Glu Met Arg Gly Lys Leu Ala Ile Gly Ile
                 230                 235                 240

 Thr Ala Asn Phe Val Asn Gly Arg Thr Val Glu Glu Thr Gln Val
                 245                 250                 255

 Pro Glu Ile Ser Gly Val Ala Arg Ile Tyr Asn Gln Ser Phe Phe
                 260                 265                 270

 Gln Ser Leu Leu Lys Ala Thr Gly Ile Asp Leu Glu Asn Ile Val
                 275                 280                 285

 Tyr Tyr Lys Asp Asp Thr His Tyr Phe Val Met Thr Ala Lys Lys
                 290                 295                 300

 Gln Cys Leu Leu Arg Leu Gly Val Leu Arg Gln Asp Trp Pro Asp
                 305                 310                 315

 Thr Asn Arg Leu Leu Gly Ser Ala Asn Val Val Pro Glu Ala Leu
                 320                 325                 330

 Gln Arg Phe Thr Arg Ala Ala Ala Asp Phe Ala Thr His Gly Lys
                 335                 340                 345

 Leu Gly Lys Leu Glu Phe Ala Gln Asp Ala His Gly Gln Pro Asp
                 350                 355                 360

 Val Ser Ala Phe Asp Phe Thr Ser Met Met Arg Ala Glu Ser Ser
                 365                 370                 375

 Ala Arg Val Gln Glu Lys His Gly Ala Arg Leu Leu Leu Gly Leu
                 380                 385                 390

 Val Gly Asp Cys Leu Val Glu Pro Phe Trp Pro Leu Gly Thr Gly
                 395                 400                 405

 Val Ala Arg Gly Phe Leu Ala Ala Phe Asp Ala Ala Trp Met Val
                 410                 415                 420

 Lys Arg Trp Ala Glu Gly Ala Glu Ser Leu Glu Val Leu Ala Glu
                 425                 430                 435

 Arg Glu Ser Leu Tyr Gln Leu Leu Ser Gln Thr Ser Pro Glu Asn
                 440                 445                 450

 Met His Arg Asn Val Ala Gln Tyr Gly Leu Asp Pro Ala Thr Arg
                 455                 460                 465

 Tyr Pro Asn Leu Asn Leu Arg Ala Val Thr Pro Asn Gln Val Arg
                 470                 475                 480

 Asp Leu Tyr Asp Val Leu Ala Lys Glu Pro Val Gln Arg Asn Asn
                 485                 490                 495

 Asp Lys Thr Asp Thr Gly Met Pro Ala Thr Gly Ser Ala Gly Thr
                 500                 505                 510

 Gln Glu Glu Leu Leu Arg Trp Cys Gln Glu Gln Thr Ala Gly Tyr
                 515                 520                 525

 Pro Gly Val His Val Ser Asp Leu Ser Ser Ser Trp Ala Asp Gly
                 530                 535                 540

 Leu Ala Leu Cys Ala Leu Val Tyr Arg Leu Gln Pro Gly Leu Leu
                 545                 550                 555

 Glu Pro Ser Glu Leu Gln Gly Leu Gly Ala Leu Glu Ala Thr Ala
                 560                 565                 570

 Trp Ala Leu Lys Val Ala Glu Asn Glu Leu Gly Ile Thr Pro Val
                 575                 580                 585

 Val Ser Ala Gln Ala Val Val Ala Gly Ser Asp Pro Leu Gly Leu
                 590                 595                 600

 Ile Ala Tyr Leu Ser His Phe His Ser Ala Phe Lys Ser Met Ala
                 605                 610                 615

 His Ser Pro Gly Pro Val Ser Gln Ala Ser Pro Gly Thr Ser Ser
                 620                 625                 630

 Ala Val Leu Phe Leu Ser Lys Leu Gln Arg Thr Leu Gln Arg Ser
                 635                 640                 645

 Arg Ala Lys Glu Asn Ala Glu Asp Ala Gly Gly Lys Lys Leu Arg
                 650                 655                 660

 Leu Glu Met Glu Ala Glu Thr Pro Ser Thr Glu Val Pro Pro Asp
                 665                 670                 675

 Pro Glu Pro Gly Val Pro Leu Thr Pro Pro Ser Gln His Gln Glu
                 680                 685                 690

 Ala Gly Ala Gly Asp Leu Cys Ala Leu Cys Gly Glu His Leu Tyr
                 695                 700                 705

 Val Leu Glu Arg Leu Cys Val Asn Gly His Phe Phe His Arg Ser
                 710                 715                 720

 Cys Phe Arg Cys His Thr Cys Glu Ala Thr Leu Trp Pro Gly Gly
                 725                 730                 735

 Tyr Glu Gln His Pro Gly Asp Gly His Phe Tyr Cys Leu Gln His
                 740                 745                 750

 Leu Pro Gln Thr Asp His Lys Lys Glu Gly Ser Asp Arg Gly Pro
                 755                 760                 765

 Glu Ser Pro Glu Leu Pro Thr Pro Ser Glu Asn Ser Met Pro Pro
                 770                 775                 780

 Gly Leu Ser Thr Pro Thr Ala Ser Gln Glu Gly Ala Gly Pro Val
                 785                 790                 795

 Pro Asp Pro Ser Gln Pro Thr Arg Arg Gln Ile Arg Leu Ser Ser
                 800                 805                 810

 Pro Glu Arg Gln Arg Leu Ser Ser Leu Asn Leu Thr Pro Asp Pro
                 815                 820                 825

 Glu Met Glu Pro Pro Pro Lys Pro Pro Arg Ser Cys Ser Ala Leu
                 830                 835                 840

 Ala Arg His Ala Leu Glu Ser Ser Phe Val Gly Trp Gly Leu Pro
                 845                 850                 855

 Val Gln Ser Pro Gln Ala Leu Val Ala Met Glu Lys Glu Glu Lys
                 860                 865                 870

 Glu Ser Pro Phe Ser Ser Glu Glu Glu Glu Glu Asp Val Pro Leu
                 875                 880                 885

 Asp Ser Asp Val Glu Gln Ala Leu Gln Thr Phe Ala Lys Thr Ser
                 890                 895                 900

 Gly Thr Met Asn Asn Tyr Pro Thr Trp Arg Arg Thr Leu Leu Arg
                 905                 910                 915

 Arg Ala Lys Glu Glu Glu Met Lys Arg Phe Cys Lys Ala Gln Thr
                 920                 925                 930

 Ile Gln Arg Arg Leu Asn Glu Ile Glu Ala Ala Leu Arg Glu Leu
                 935                 940                 945

 Glu Ala Glu Gly Val Lys Leu Glu Leu Ala Leu Arg Arg Gln Ser
                 950                 955                 960

 Ser Ser Pro Glu Gln Gln Lys Lys Leu Trp Val Gly Gln Leu Leu
                 965                 970                 975

 Gln Leu Val Asp Lys Lys Asn Ser Leu Val Ala Glu Glu Ala Glu
                 980                 985                 990

 Leu Met Ile Thr Val Gln Glu Leu Asn Leu Glu Glu Lys Gln Trp
                 995                1000                1005

 Gln Leu Asp Gln Glu Leu Arg Gly Tyr Met Asn Arg Glu Glu Asn
                1010                1015                1020

 Leu Lys Thr Ala Ala Asp Arg Gln Ala Glu Asp Gln Val Leu Arg
                1025                1030                1035

 Lys Leu Val Asp Leu Val Asn Gln Arg Asp Ala Leu Ile Arg Phe
                1040                1045                1050

 Gln Glu Glu Arg Arg Leu Ser Glu Leu Ala Leu Gly Thr Gly Ala
                1055                1060                1065

 Gln Gly


<210> 6146
<211> 3103
<212> DNA
<213> Homo sapien

<400> 6146
 ctgtgacact gccagcagcg cgcagaggga gggatggggg cgggtatcgg 50

 cgtaggggcc ctcggaaaga acggatattg ctgtgacacc gcggggacgc 100

 tctgaaggga cgagtgtcgg tgtggcaccg gtgcacgctg aaggagccgg 150

 cggaaccggg tggccatggg gatgtgggca tcgctggacg ctttgtggga 200

 gatgccggcc gagaagcgta tcttcggggc cgtgctgctc ttttcctgga 250

 cagtgtatct ttgggagacc ttcctagcac agcggcagag aaggatatat 300

 aaaacaacaa ctcatgtacc accggagtta ggacagatca tggattctga 350

 aacatttgag aaatctcgac tctatcaact ggataaaagc actttcagct 400

 tctggtcagg actctattca gagactgaag gcactcttat tcttctcttt 450

 ggaggaatac cttatctctg gagactttct ggacggttct gtggttatgc 500

 tggctttgga ccagaatatg agatcactca gtccctggtg tttctgctgt 550

 tggctacact tttcagtgca ttgactggtt tgccatggag tctttataat 600

 acttttgtga tagaagaaaa acatggcttc aatcaacaga ctttggggtt 650

 cttcatgaaa gatgcaatca agaaatttgt tgtgactcag tgtattttgt 700

 tgcctgtgtc ttcacttcta ctttacatta ttaaaattgg gggtgactat 750

 ttttttattt atgcctggct gttcacatta gttgtgtctc tggttcttgt 800

 cacaatctat gctgattata ttgccccttt atttgacaaa ttcacacctc 850

 tgcctgaggg aaagcttaaa gaagaaattg aagtaatggc aaagagtatt 900

 gactttcctt tgacgaaggt gtatgttgtg gaaggatcta aacgctcttc 950

 ccacagcaat gcttattttt atggcttctt caagaacaag cgaatagttt 1000

 tgtttgacac tctactagaa gagtactctg tactaaacaa agacatccag 1050

 gaggattctg gcatggaacc ccgcaatgag gaagaaggga acagtgaaga 1100

 aataaaagct aaagttaaaa ataagaaaca aggatgtaaa aatgaggagg 1150

 tactcgctgt actaggccat gaactggggc actggaagtt gggacataca 1200

 gtcaaaaata tcattattag ccagatgaat tctttcctgt gttttttttt 1250

 atttgctgta ttaattggtc gaaaggagct ttttgctgca tttggttttt 1300

 atgatagcca acccactctt attggactat tgatcatctt ccagtttatt 1350

 ttttcacctt acaatgaggt tctttctttt tgcctaacag tcctaagccg 1400

 cagatttgag tttcaagctg atgcatttgc caagaaactt gggaaggcta 1450

 aagacttata ttctgcttta atcaaactta acaaagataa cttgggattc 1500

 cctgtttctg actggttgtt ctcaatgtgg cattattctc atcctccact 1550

 gctagagaga cttcaagctt tgaaaactat gaagcaacac tgagatgtcc 1600

 aggatctgtg actgaagaca tttctgatta tttctgtcct ggcagcatgt 1650

 tccagctctt gatgttttta aacttttttt tagaagaaaa attaagtaca 1700

 gaaaagccca gatttaaata catttaatat gtcattttaa aaatgatttt 1750

 aataattcat ttcttaaaac actgaatgaa ttttgaagct taatgttttt 1800

 aaaggcatag ttttatcttt gacatctaat ttaccatcaa gttgtaaaat 1850

 tatttggaaa aatacagaac tcgttttatt tgtatactta tatggaatct 1900

 gcatgtgagg tgtttgaggg catatgtttg aaagagggag catcaccaca 1950

 ggaatccttt ctgtgaggtg gaaacagtgg tcctgaatca ttgtgctcac 2000

 acctaacttg aaatctggtc ttactttcat gctgttatga tttcacctgg 2050

 tgaatcagtg ttttaaataa gaaaggtaat agttggtaag gccaatgtta 2100

 tttaaatgaa agtagttaga aaaatgctct cctattctac caaattttta 2150

 atttctttct tccctttctt gctacacagt gatcaagagt ttctcatagt 2200

 gctttgaagt tagaaattat gtataggata ttttaaatca ttgagttttg 2250

 tggggttttt ttgtttgttt gtttcttttg ttttttggaa aatccgtgtc 2300

 tttatctttt tttcccacgt ggtagatatg atcccattgg aggtaaattg 2350

 tagcttcttc tcattcatgc agtaaataat acatcctttc actcagcaga 2400

 gatggccata ttaaacacgt tttgctatgt taaaagtggc agaacaggaa 2450

 agacgaatta aaaataacat tttttaagcg acataaggat gaaatactga 2500

 tgaatctctg tgacattaca gggaaaaaaa tatagttttc tatctctttc 2550

 aagggcagaa gagttttcat ttttattttt gtaattttat ctgtaagtca 2600

 taaatattac ttaatcaggc ctgattctac ttttgaaaat tacagttctt 2650

 gaaatgcaga taatgtttac tttgaaaaca aatgtcatga atgatttcca 2700

 gtttttaaag ctatatgttt cactgcttca tatctctgtc cactttctga 2750

 atgagaactt attttgtgcc tagagctctc actcactgat aatgcttatt 2800

 accttctggg catttattcc aaagtgggat caactgtacg cctttggtat 2850

 ctgaccataa agtcttttgc tccgctgaca tttgggtgat gtcttcacat 2900

 ggaaatataa taaaaataaa aatctagttt aatactgcat tatttatttt 2950

 cctaaggcta aagaggagca gtcctatgct tttattcagc atcctttatc 3000

 tgtgacttca tgctctgata actgcctttc cttccttctg tgcctttgaa 3050

 tacaaatttc agttctgcaa aagtgaaaca ttaaacattg ccaacgcaaa 3100

 tgt 3103

<210> 6147
<211> 475
<212> PRT
<213> Homo sapien

<400> 6147
 Met Gly Met Trp Ala Ser Leu Asp Ala Leu Trp Glu Met Pro Ala
   1               5                  10                  15

 Glu Lys Arg Ile Phe Gly Ala Val Leu Leu Phe Ser Trp Thr Val
                  20                  25                  30

 Tyr Leu Trp Glu Thr Phe Leu Ala Gln Arg Gln Arg Arg Ile Tyr
                  35                  40                  45

 Lys Thr Thr Thr His Val Pro Pro Glu Leu Gly Gln Ile Met Asp
                  50                  55                  60

 Ser Glu Thr Phe Glu Lys Ser Arg Leu Tyr Gln Leu Asp Lys Ser
                  65                  70                  75

 Thr Phe Ser Phe Trp Ser Gly Leu Tyr Ser Glu Thr Glu Gly Thr
                  80                  85                  90

 Leu Ile Leu Leu Phe Gly Gly Ile Pro Tyr Leu Trp Arg Leu Ser
                  95                 100                 105

 Gly Arg Phe Cys Gly Tyr Ala Gly Phe Gly Pro Glu Tyr Glu Ile
                 110                 115                 120

 Thr Gln Ser Leu Val Phe Leu Leu Leu Ala Thr Leu Phe Ser Ala
                 125                 130                 135

 Leu Thr Gly Leu Pro Trp Ser Leu Tyr Asn Thr Phe Val Ile Glu
                 140                 145                 150

 Glu Lys His Gly Phe Asn Gln Gln Thr Leu Gly Phe Phe Met Lys
                 155                 160                 165

 Asp Ala Ile Lys Lys Phe Val Val Thr Gln Cys Ile Leu Leu Pro
                 170                 175                 180

 Val Ser Ser Leu Leu Leu Tyr Ile Ile Lys Ile Gly Gly Asp Tyr
                 185                 190                 195

 Phe Phe Ile Tyr Ala Trp Leu Phe Thr Leu Val Val Ser Leu Val
                 200                 205                 210

 Leu Val Thr Ile Tyr Ala Asp Tyr Ile Ala Pro Leu Phe Asp Lys
                 215                 220                 225

 Phe Thr Pro Leu Pro Glu Gly Lys Leu Lys Glu Glu Ile Glu Val
                 230                 235                 240

 Met Ala Lys Ser Ile Asp Phe Pro Leu Thr Lys Val Tyr Val Val
                 245                 250                 255

 Glu Gly Ser Lys Arg Ser Ser His Ser Asn Ala Tyr Phe Tyr Gly
                 260                 265                 270

 Phe Phe Lys Asn Lys Arg Ile Val Leu Phe Asp Thr Leu Leu Glu
                 275                 280                 285

 Glu Tyr Ser Val Leu Asn Lys Asp Ile Gln Glu Asp Ser Gly Met
                 290                 295                 300

 Glu Pro Arg Asn Glu Glu Glu Gly Asn Ser Glu Glu Ile Lys Ala
                 305                 310                 315

 Lys Val Lys Asn Lys Lys Gln Gly Cys Lys Asn Glu Glu Val Leu
                 320                 325                 330

 Ala Val Leu Gly His Glu Leu Gly His Trp Lys Leu Gly His Thr
                 335                 340                 345

 Val Lys Asn Ile Ile Ile Ser Gln Met Asn Ser Phe Leu Cys Phe
                 350                 355                 360

 Phe Leu Phe Ala Val Leu Ile Gly Arg Lys Glu Leu Phe Ala Ala
                 365                 370                 375

 Phe Gly Phe Tyr Asp Ser Gln Pro Thr Leu Ile Gly Leu Leu Ile
                 380                 385                 390

 Ile Phe Gln Phe Ile Phe Ser Pro Tyr Asn Glu Val Leu Ser Phe
                 395                 400                 405

 Cys Leu Thr Val Leu Ser Arg Arg Phe Glu Phe Gln Ala Asp Ala
                 410                 415                 420

 Phe Ala Lys Lys Leu Gly Lys Ala Lys Asp Leu Tyr Ser Ala Leu
                 425                 430                 435

 Ile Lys Leu Asn Lys Asp Asn Leu Gly Phe Pro Val Ser Asp Trp
                 440                 445                 450

 Leu Phe Ser Met Trp His Tyr Ser His Pro Pro Leu Leu Glu Arg
                 455                 460                 465

 Leu Gln Ala Leu Lys Thr Met Lys Gln His
                 470                 475

<210> 6148
<211> 2095
<212> DNA
<213> Homo sapien

<400> 6148
 gcgcctgtca gggaagcggc gcgcgcgcgc gggcggcggg cgggctgggg 50

 atccgccgcg cagtgccagc gccagcgcca gacccgcgcc ccgcgctctc 100

 cggcccgtcg cctgccttgg gactcgcgag cccgcactcc cgccctgcct 150

 gttcgctgcc cgagtatgga gctgctgtgt tgcgaaggca cccggcacgc 200

 gccccgggcc gggccggacc cgcggctgct gggggaccag cgtgtcctgc 250

 agagcctgct ccgcctggag gagcgctacg taccccgcgc ctcctacttc 300

 cagtgcgtgc agcgggagat caagccgcac atgcggaaga tgctggctta 350

 ctggatgctg gaggtatgtg aggagcagcg ctgtgaggag gaagtcttcc 400

 ccctggccat gaactacctg gatcgctacc tgtcttgcgt ccccacccga 450

 aaggcgcagt tgcagctcct gggtgcggtc tgcatgctgc tggcctccaa 500

 gctgcgcgag accacgcccc tgaccatcga aaaactgtgc atctacaccg 550

 accacgctgt ctctccccgc cagttgcggg actgggaggt gctggtccta 600

 gggaagctca agtgggacct ggctgctgtg attgcacatg atttcctggc 650

 cttcattctg caccggctct ctctgccccg tgaccgacag gccttggtca 700

 aaaagcatgc ccagaccttt ttggccctct gtgctacaga ttataccttt 750

 gccatgtacc cgccatccat gatcgccacg ggcagcattg gggctgcagt 800

 gcaaggcctg ggtgcctgct ccatgtccgg ggatgagctc acagagctgc 850

 tggcagggat cactggcact gaagtggact gcctgcgggc ctgtcaggag 900

 cagatcgaag ctgcactcag ggagagcctc agggaagcct ctcagaccag 950

 ctccagccca gcgcccaaag ccccccgggg ctccagcagc caagggccca 1000

 gccagaccag cactcctaca gatgtcacag ccatacacct gtagccctgg 1050

 agaggccctc tggagtggcc actaagcaga ggaggggccg ctgccaccca 1100

 cctccctgcc tccaggaacc acaccacatc taagcctgaa ggggcgtctg 1150

 ttcccccttc acaaagccca agggatctgg tcctacccat ccccgcagtg 1200

 tgcactaagg ggcccggcca gccatgtctg catttcggtg gctagtcaag 1250

 ctcctcctcc ctgcatctga ccagcagcgc ctttcccaac tctagctggg 1300

 ggtgggccag gctgatggga cagaattgga tacatacacc agcattcctt 1350

 ttgaacgccc ccccccaccc ctgggggctc tcatgttttc aactgccaaa 1400

 atgctctagt gccttctaaa ggtgttgtcc cttctagggt tattgcattt 1450

 ggattggggt ccctctaaaa tttaatgcat gatagacaca tatgaggggg 1500

 aatagtctag atggctcctc tcagtacttt ggaggcccct atgtagtccg 1550

 tgctgacagc tgctcctaga gggaggggcc taggcctcag ccagagaagc 1600

 tataaattcc tctttgcttt gctttctgct cagcttctcc tgtgtgattg 1650

 acagctttgc tgctgaaggc tcattttaat ttattaattg ctttgagcac 1700

 aactttaaga ggacataatg ggggcctggc catcccacaa gtggtggtaa 1750

 ccctggtggt tgctgttttc ctcccttctg ctactggcaa aaggatcttt 1800

 gtggccaagg agctgctata gcctggggtg gggtcatgcc ctcctctccc 1850

 attgtccctc tgccccatcc tccagcaggg aaaatgcagc agggatgccc 1900

 tggaggtggc tgagcccctg tctagagagg gaggcaagcc ctgttgacac 1950

 aggtctttcc taaggctgca aggtttaggc tggtggccca ggaccatcat 2000

 cctactgtaa taaagatgat tgtgaaataa aactggcttt ggcttcttgg 2050

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 2095

<210> 6149
<211> 292
<212> PRT
<213> Homo sapien

<400> 6149
 Met Glu Leu Leu Cys Cys Glu Gly Thr Arg His Ala Pro Arg Ala
   1               5                  10                  15

 Gly Pro Asp Pro Arg Leu Leu Gly Asp Gln Arg Val Leu Gln Ser
                  20                  25                  30

 Leu Leu Arg Leu Glu Glu Arg Tyr Val Pro Arg Ala Ser Tyr Phe
                  35                  40                  45

 Gln Cys Val Gln Arg Glu Ile Lys Pro His Met Arg Lys Met Leu
                  50                  55                  60

 Ala Tyr Trp Met Leu Glu Val Cys Glu Glu Gln Arg Cys Glu Glu
                  65                  70                  75

 Glu Val Phe Pro Leu Ala Met Asn Tyr Leu Asp Arg Tyr Leu Ser
                  80                  85                  90

 Cys Val Pro Thr Arg Lys Ala Gln Leu Gln Leu Leu Gly Ala Val
                  95                 100                 105

 Cys Met Leu Leu Ala Ser Lys Leu Arg Glu Thr Thr Pro Leu Thr
                 110                 115                 120

 Ile Glu Lys Leu Cys Ile Tyr Thr Asp His Ala Val Ser Pro Arg
                 125                 130                 135

 Gln Leu Arg Asp Trp Glu Val Leu Val Leu Gly Lys Leu Lys Trp
                 140                 145                 150

 Asp Leu Ala Ala Val Ile Ala His Asp Phe Leu Ala Phe Ile Leu
                 155                 160                 165

 His Arg Leu Ser Leu Pro Arg Asp Arg Gln Ala Leu Val Lys Lys
                 170                 175                 180

 His Ala Gln Thr Phe Leu Ala Leu Cys Ala Thr Asp Tyr Thr Phe
                 185                 190                 195

 Ala Met Tyr Pro Pro Ser Met Ile Ala Thr Gly Ser Ile Gly Ala
                 200                 205                 210

 Ala Val Gln Gly Leu Gly Ala Cys Ser Met Ser Gly Asp Glu Leu
                 215                 220                 225

 Thr Glu Leu Leu Ala Gly Ile Thr Gly Thr Glu Val Asp Cys Leu
                 230                 235                 240

 Arg Ala Cys Gln Glu Gln Ile Glu Ala Ala Leu Arg Glu Ser Leu
                 245                 250                 255

 Arg Glu Ala Ser Gln Thr Ser Ser Ser Pro Ala Pro Lys Ala Pro
                 260                 265                 270

 Arg Gly Ser Ser Ser Gln Gly Pro Ser Gln Thr Ser Thr Pro Thr
                 275                 280                 285

 Asp Val Thr Ala Ile His Leu
                 290

<210> 6150
<211> 4020
<212> DNA
<213> Homo sapien

<400> 6150
 gtcaattgcc ctttagtccc aggactaacc ggaagcttct gcaacaggag 50

 gacattgaaa ataagatgga acccatccac ataaggattt gcctcaaagg 100

 gcactgcaaa aattgaacag aggaatccca aggaagctgc ctgaatttgc 150

 ctgtatactc tcgttctgcg acttataaag gaccagacaa atcaaattag 200

 tggttttggt ttccgccagc tgtggatgcc tttgacatta tgaccgcaga 250

 ggattccacc gcagccatga gcagtgactc ggccgccggg tcctcggcca 300

 aggtgcccga gggcgtggcg ggcgcgccca acgaggcagc actgctggcg 350

 ctgatggagc gcacgggcta cagcatggtg caagagaacg ggcagcgcaa 400

 gtacggcggc ccaccgcccg gctgggaggg cccgcacccg cagcgtggct 450

 gcgaggtctt cgtgggcaag atcccgcgcg acgtgtacga ggacgagctg 500

 gtgcccgtgt tcgaggccgt gggccgcacc tacgagctgc gcctcatgat 550

 ggactttgac ggcaagaacc gcggctacgc cttcgtcatg tactgccaca 600

 agcacgaggc caagcgcgca gtgcgtgagc tcaacaacta cgagatccgc 650

 ccgggccgcc tgctcggcgt gtgctgcagc gtggacaact gccgcctctt 700

 catcggcggg atccccaaga tgaagaagcg cgaggaaatc ctggaggaga 750

 ttgccaaggt caccgagggc gtgctggacg tgatcgtcta cgccagcgcg 800

 gccgacaaga tgaagaaccg cggcttcgcc ttcgtggagt acgagagcca 850

 ccgcgcggct gccatggctc gccgcaagct catgcctggc cgcatccagc 900

 tgtggggcca ccagatcgcc gtggactggg ccgagcctga gatcgacgtg 950

 gacgaggacg tgatggagac cgtgaagatc ctctacgtgc gcaacctcat 1000

 gatcgagacc accgaggaca ccatcaagaa gagcttcggc cagttcaacc 1050

 ccggctgcgt ggagcgcgtc aagaagatcc gcgactacgc cttcgtgcac 1100

 ttcaccagcc gcgaggatgc cgtgcatgcc atgaacaacc tcaacggcac 1150

 tgagctggag ggctcgtgcc tggaggtcac gctggccaag cccgtggaca 1200

 aggagcagta ctcgcgctac cagaaggcag ccaggggcgg cggcgcggct 1250

 gaggcagcgc agcagcccag ctacgtgtac tcctgcgacc cctacacact 1300

 ggcctactac ggctacccct acaacgcgct cattgggccc aacagggact 1350

 actttgtgaa agtagccatc cctgccattg gggctcagta ttccatgttt 1400

 ccagcagctc cagcccctaa aatgattgaa gatggcaaaa tccacacagt 1450

 ggagcacatg atcagcccca ttgctgtgca gccagaccca gccagtgctg 1500

 ctgccgccgc agccgcggcc gcagccgccg cagccgctgt cattcccact 1550

 gtgtcgacgc caccaccttt ccagggccgc ccaataactc cagtatacac 1600

 ggtggctcca aacgttcaga gaattcctac tgccgggatc tacggggcca 1650

 gttacgtgcc atttgctgct ccagctacag ccacgatcgc cacactacag 1700

 aagaacgcgg cagccgcggc cgccgtgtat ggaggatacg caggctacat 1750

 acctcaggcc ttccctgctg ctgccattca ggtccccatc cccgacgtct 1800

 accagacata ctgaggctgg tgaccagcac gaagacagac cacacaaaca 1850

 ccactgaagg aacgcttgac tatttatgaa gaaggaacat gttggattca 1900

 cacatgcaac ctgaaagtga agaatgttag cagatttatt tctgaattat 1950

 tttatataca tgaagttttc actagttttt taagactatt ttcaacttag 2000

 catgcctacg ttcatacatt tccaaaagac ttgcaatggt tcgtgccttc 2050

 attccatctt ttaaaaattt gtatgctgta ctacatttgt atagaggttt 2100

 ttgttgttgt ttttttaagg atatattttc agtatgaagg ttattttctt 2150

 aacttctgca ctccagagat ttctattttg tagtaccttc aataatatat 2200

 caactatata ttaaaaaagc acacttgagg agctagggaa ctattttgaa 2250

 aaatatatac aatatttaaa gatacaaaca gtagtgctta aaaatactac 2300

 ataaagcatt attttaaagg ttatactgga aagtgcaatt ttaaaatgag 2350

 taaaacctct gtatttctgc tggcattaag ggttgatggt gttaccatgt 2400

 atcatcatgg cggtactatt ttttaaaaga aattaaacac tggatctctc 2450

 cttaagccaa cattgaaaag acttgccgca cttctgagtc caaacactgg 2500

 aaagctctcc ttgccaccgt tagccggggc tcattctcca tgtgccttag 2550

 ccttaaacat gcccccactc ccacatctct caccctgtcc cctcctcccc 2600

 agattcccaa tcccaccgca atgtttggca agcctaggac tgataagtag 2650

 ctctgataga ggagctggtg gcttttatac ttcttcctgg gtttttgttg 2700

 gggtttgttg tttcgttgtt ttttgttttt tttttgtttg gttggggaag 2750

 tattgtcttc tacgtgtgct attttcagta gcagagtaag cacaaggttt 2800

 taatcgagtt gcataagaca cctttgcata gctatttaat tgcccaatgt 2850

 aaaactttaa tgccatttct aatgctttta ttcatttttg aagtatgagt 2900

 ttgtagggac aaagaatgta tgttatcgta gacaagaccc ccagagactc 2950

 ttttcagcag aaagttatgc ttctagttgc cttaccatgt ttcttgcaaa 3000

 actgtccatg gtcctcaagg gtgttggaaa cattatgttt attaaatggg 3050

 cctctcttcc tttgctgtgc acttgatggg tgaactggat tggggtgtgc 3100

 acatccagga ggaggaggag agacctgtag aagtttaaag atagtttgta 3150

 aatatcttct aatgcttgtt tttagtcctt ttatgttgga gaagttcatg 3200

 gtatgtagtt taatgcaaaa tgaaaccatt ttatttcaat gttattaaaa 3250

 aggtttgttt tattaggaag ttaatgtatt gttgcagtgt tttgtgcctg 3300

 tttaaaggct tttgtttagc agagtgaatg taaaatacag taaaatgtta 3350

 agattgtcat ctacttttta aaaaaaaata tcaacttgga attgtttttt 3400

 aaaggctcaa tcaaggaagt gaggtgtgca ataaggtagc aagtaaaacg 3450

 cagttgcgtt tttatgtcat gttagagatc catacaattt tccactcacg 3500

 ggatttttgt tgatggctga attcttgtgg attcataaga ggatcatgcc 3550

 cttagcaagt acttttgttt tgttttaaat taagagattc ccaaatgcct 3600

 ttttccccct catcttgaaa tgagatgagt ttttatgtgt aagcaatatt 3650

 tatttaacta ttctataaaa ttattgagtg cctactgagg cctttaagca 3700

 ccgctaacat tcctttccat cattcttttg aatgacataa aataattgtg 3750

 caatgttcct gatgatgtac cccacagctg cattcaaact caaatctgtg 3800

 ggaatgagtg actcgaccaa atgtaattcg gatcagatcc tcatcccctg 3850

 actgtgtgaa aaaagtactc tccttctagt gaaggattgt cacagagttt 3900

 cactggatga aactatgacc cagtattctt actgtatttt acatgtgcct 3950

 gtaaattatt ttgccgaaat aagaagaaga agaggaagaa agaacagtag 4000

 aaaaaaaaaa taaaaaaaaa 4020

<210> 6151
<211> 524
<212> PRT
<213> Homo sapien

<400> 6151
 Met Thr Ala Glu Asp Ser Thr Ala Ala Met Ser Ser Asp Ser Ala
   1               5                  10                  15

 Ala Gly Ser Ser Ala Lys Val Pro Glu Gly Val Ala Gly Ala Pro
                  20                  25                  30

 Asn Glu Ala Ala Leu Leu Ala Leu Met Glu Arg Thr Gly Tyr Ser
                  35                  40                  45

 Met Val Gln Glu Asn Gly Gln Arg Lys Tyr Gly Gly Pro Pro Pro
                  50                  55                  60

 Gly Trp Glu Gly Pro His Pro Gln Arg Gly Cys Glu Val Phe Val
                  65                  70                  75

 Gly Lys Ile Pro Arg Asp Val Tyr Glu Asp Glu Leu Val Pro Val
                  80                  85                  90

 Phe Glu Ala Val Gly Arg Thr Tyr Glu Leu Arg Leu Met Met Asp
                  95                 100                 105

 Phe Asp Gly Lys Asn Arg Gly Tyr Ala Phe Val Met Tyr Cys His
                 110                 115                 120

 Lys His Glu Ala Lys Arg Ala Val Arg Glu Leu Asn Asn Tyr Glu
                 125                 130                 135

 Ile Arg Pro Gly Arg Leu Leu Gly Val Cys Cys Ser Val Asp Asn
                 140                 145                 150

 Cys Arg Leu Phe Ile Gly Gly Ile Pro Lys Met Lys Lys Arg Glu
                 155                 160                 165

 Glu Ile Leu Glu Glu Ile Ala Lys Val Thr Glu Gly Val Leu Asp
                 170                 175                 180

 Val Ile Val Tyr Ala Ser Ala Ala Asp Lys Met Lys Asn Arg Gly
                 185                 190                 195

 Phe Ala Phe Val Glu Tyr Glu Ser His Arg Ala Ala Ala Met Ala
                 200                 205                 210

 Arg Arg Lys Leu Met Pro Gly Arg Ile Gln Leu Trp Gly His Gln
                 215                 220                 225

 Ile Ala Val Asp Trp Ala Glu Pro Glu Ile Asp Val Asp Glu Asp
                 230                 235                 240

 Val Met Glu Thr Val Lys Ile Leu Tyr Val Arg Asn Leu Met Ile
                 245                 250                 255

 Glu Thr Thr Glu Asp Thr Ile Lys Lys Ser Phe Gly Gln Phe Asn
                 260                 265                 270

 Pro Gly Cys Val Glu Arg Val Lys Lys Ile Arg Asp Tyr Ala Phe
                 275                 280                 285

 Val His Phe Thr Ser Arg Glu Asp Ala Val His Ala Met Asn Asn
                 290                 295                 300

 Leu Asn Gly Thr Glu Leu Glu Gly Ser Cys Leu Glu Val Thr Leu
                 305                 310                 315

 Ala Lys Pro Val Asp Lys Glu Gln Tyr Ser Arg Tyr Gln Lys Ala
                 320                 325                 330

 Ala Arg Gly Gly Gly Ala Ala Glu Ala Ala Gln Gln Pro Ser Tyr
                 335                 340                 345

 Val Tyr Ser Cys Asp Pro Tyr Thr Leu Ala Tyr Tyr Gly Tyr Pro
                 350                 355                 360

 Tyr Asn Ala Leu Ile Gly Pro Asn Arg Asp Tyr Phe Val Lys Val
                 365                 370                 375

 Ala Ile Pro Ala Ile Gly Ala Gln Tyr Ser Met Phe Pro Ala Ala
                 380                 385                 390

 Pro Ala Pro Lys Met Ile Glu Asp Gly Lys Ile His Thr Val Glu
                 395                 400                 405

 His Met Ile Ser Pro Ile Ala Val Gln Pro Asp Pro Ala Ser Ala
                 410                 415                 420

 Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Val Ile
                 425                 430                 435

 Pro Thr Val Ser Thr Pro Pro Pro Phe Gln Gly Arg Pro Ile Thr
                 440                 445                 450

 Pro Val Tyr Thr Val Ala Pro Asn Val Gln Arg Ile Pro Thr Ala
                 455                 460                 465

 Gly Ile Tyr Gly Ala Ser Tyr Val Pro Phe Ala Ala Pro Ala Thr
                 470                 475                 480

 Ala Thr Ile Ala Thr Leu Gln Lys Asn Ala Ala Ala Ala Ala Ala
                 485                 490                 495

 Val Tyr Gly Gly Tyr Ala Gly Tyr Ile Pro Gln Ala Phe Pro Ala
                 500                 505                 510

 Ala Ala Ile Gln Val Pro Ile Pro Asp Val Tyr Gln Thr Tyr
                 515                 520

<210> 6152
<211> 2844
<212> DNA
<213> Homo sapien

<400> 6152
 acccaaccct gtcattattt cccctccgac tgggccggtg ccatcggaaa 50

 ccggagtgac cagaggaggg acacgcatcc aatttcactg ggctgcaaga 100

 tatcaataag ccttgcctct ttaaactact tatgtacaaa taaaagtgat 150

 ggtgagaacc tggctcagga aatgcagtag caggccatat tgcatccaaa 200

 ggaattactc acagctgtgc tgtgtgcatt ctctgtgggc ctagcaggga 250

 aggggacagc cctgtggcaa tgggcatgac acggatgctc ctggaatgca 300

 gtctcagtga caagttgtgt gtcatccagg agaagcagta tgaagtgatt 350

 atcgtcccaa ctttgttggt tactatcttc ctcatccttc ttggggtcat 400

 cctgtggctt tttatcagag aacaaagaac tcaacagcag cgttctggac 450

 ctcaaggcat tgcccctgtt cctccaccta gggacctaag ctgggaagca 500

 ggacatggag gaaatgtggc tttgccactt aaggagacat ccgtggaaaa 550

 ctttctggga gctaccacac ctgccctggc taagctgcag gtgccgcggg 600

 agcaactctc tgaagttctg gagcagattt gcagtggtag ctgtgggccc 650

 atctttcgag ccaatatgaa cactggggac ccttctaagc ccaagagtgt 700

 tattctcaag gctttaaaag aaccagctgg gctccatgag gtacaagatt 750

 tcttagggcg aatccaattc catcaatacc tggggaaaca caaaaacctg 800

 gtgcagctgg aaggctgctg cactgaaaag ctgccactct atatggtgtt 850

 ggaggatgtg gcccaggggg acctgctcgg ctttctctgg acctgtcggc 900

 gggatgtgat gactatggat ggtcttctct atgatctcac agaaaaacaa 950

 gtatatcaca tcggaaagca ggtccttttg gcgctggaat tcctgcagga 1000

 gaagcatttg ttccatgggg atgtggcagc caggaatatt ctgatgcaaa 1050

 gtgatctcac tgctaagctc tgtggattag gcctggctta tgaagtttac 1100

 acccgagggg ccatctcctc tactcaaacc atacctctca agtggcttgc 1150

 cccagaacgg cttctcctga gacctgctag catcagagca gatgtctggt 1200

 cttttgggat cctgctctat gagatggtga ctctaggagc accaccgtat 1250

 cctgaagtcc ctcctaccag catcctagag catctccaaa gaaggaaaat 1300

 catgaagaga cccagtagct gcacacatac catgtacagt atcatgaagt 1350

 cctgctggcg ctggcgtgag gctgaccgcc cctcacctag agagctgcgc 1400

 ttgcgcctag aagctgccat taaaactgca gatgacgagg ctgtgttaca 1450

 agtaccagag ttggtggtac ctgaactgta tgcagctgtg gccggcatca 1500

 gagtggagag cctcttctac aactatagca tgctttgaag agtctcgggc 1550

 aagaaacatt catgcatgag tatatgttct tggaatcaat tcctctaaga 1600

 acagagaatg gtctttccca gggacacaaa gggagaaatg ggacatggat 1650

 tcttgatctt cctttacaca tttctcggga aatctgaaat gatgctggat 1700

 gggactctac acatcctgag ctaagacata ctgtcagtct cacttctgct 1750

 gtcccagtcc tagaaatcct gggtagaagt ggtggacctg tgcaaaggag 1800

 gttttagaac tctgcagtat ttgttggggc atggcacaaa taagctcatc 1850

 cctcccgtcc gaggctagtt tcctctggaa ccacattttt atctagatga 1900

 aaatttggaa tgaaatgaag gaatagaaat ccaataaaag agttgaaggg 1950

 aaagaaaatt taaggttctt cttgctcagg attacagata tggaccaaca 2000

 cctccttcaa gaaaaggtgg taggacacaa agttcttcag tcctgagccc 2050

 tacatgtggg gttggaggag aactataacg gaaaaacctc tgagtttcac 2100

 cttaggtata gataaaagaa agatggtccc cttttatctg attctgagac 2150

 aggtaaattc tgtttgttac tacgtttaat tagaaggtgg aggagtcatt 2200

 tcatgattaa gaacattcaa catgtattgt tcattaagct agcttcctag 2250

 ttccgattag actaaggaga ctaagcctag agagtcaatg ttagaacagt 2300

 gaaaagaatt ctgtgtgtgt gtgtgtgtgt gtgcacaata aataggaaat 2350

 gtagaaacca agcaagaagg cttagtagct cagtctttaa caagggctag 2400

 aaaagaatgt aatctgatat ggaaggatag cagcttctaa ttttcaatca 2450

 tctgttgata tactgtgaaa cttattttat taaattaata tttattaaat 2500

 ggaaatatgc ttttctggtt tataactact aaaaatatca tagggaggat 2550

 aaaagtaaat aagtgaaagt taatgccaat agaaaaattc aagagataat 2600

 gtacaatgtc agaaaaggga ttctttatgt gtaaatgggg ataataccta 2650

 tttcacaagg ttgttctgag gattgatacg ttttgagtat gtatttgtac 2700

 actatctggc acatatgcgc tcaataaacg tgtttctcct tttaaaaaaa 2750

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 2844

<210> 6153
<211> 422
<212> PRT
<213> Homo sapien

<400> 6153
 Met Gly Met Thr Arg Met Leu Leu Glu Cys Ser Leu Ser Asp Lys
   1               5                  10                  15

 Leu Cys Val Ile Gln Glu Lys Gln Tyr Glu Val Ile Ile Val Pro
                  20                  25                  30

 Thr Leu Leu Val Thr Ile Phe Leu Ile Leu Leu Gly Val Ile Leu
                  35                  40                  45

 Trp Leu Phe Ile Arg Glu Gln Arg Thr Gln Gln Gln Arg Ser Gly
                  50                  55                  60

 Pro Gln Gly Ile Ala Pro Val Pro Pro Pro Arg Asp Leu Ser Trp
                  65                  70                  75

 Glu Ala Gly His Gly Gly Asn Val Ala Leu Pro Leu Lys Glu Thr
                  80                  85                  90

 Ser Val Glu Asn Phe Leu Gly Ala Thr Thr Pro Ala Leu Ala Lys
                  95                 100                 105

 Leu Gln Val Pro Arg Glu Gln Leu Ser Glu Val Leu Glu Gln Ile
                 110                 115                 120

 Cys Ser Gly Ser Cys Gly Pro Ile Phe Arg Ala Asn Met Asn Thr
                 125                 130                 135

 Gly Asp Pro Ser Lys Pro Lys Ser Val Ile Leu Lys Ala Leu Lys
                 140                 145                 150

 Glu Pro Ala Gly Leu His Glu Val Gln Asp Phe Leu Gly Arg Ile
                 155                 160                 165

 Gln Phe His Gln Tyr Leu Gly Lys His Lys Asn Leu Val Gln Leu
                 170                 175                 180

 Glu Gly Cys Cys Thr Glu Lys Leu Pro Leu Tyr Met Val Leu Glu
                 185                 190                 195

 Asp Val Ala Gln Gly Asp Leu Leu Gly Phe Leu Trp Thr Cys Arg
                 200                 205                 210

 Arg Asp Val Met Thr Met Asp Gly Leu Leu Tyr Asp Leu Thr Glu
                 215                 220                 225

 Lys Gln Val Tyr His Ile Gly Lys Gln Val Leu Leu Ala Leu Glu
                 230                 235                 240

 Phe Leu Gln Glu Lys His Leu Phe His Gly Asp Val Ala Ala Arg
                 245                 250                 255

 Asn Ile Leu Met Gln Ser Asp Leu Thr Ala Lys Leu Cys Gly Leu
                 260                 265                 270

 Gly Leu Ala Tyr Glu Val Tyr Thr Arg Gly Ala Ile Ser Ser Thr
                 275                 280                 285

 Gln Thr Ile Pro Leu Lys Trp Leu Ala Pro Glu Arg Leu Leu Leu
                 290                 295                 300

 Arg Pro Ala Ser Ile Arg Ala Asp Val Trp Ser Phe Gly Ile Leu
                 305                 310                 315

 Leu Tyr Glu Met Val Thr Leu Gly Ala Pro Pro Tyr Pro Glu Val
                 320                 325                 330

 Pro Pro Thr Ser Ile Leu Glu His Leu Gln Arg Arg Lys Ile Met
                 335                 340                 345

 Lys Arg Pro Ser Ser Cys Thr His Thr Met Tyr Ser Ile Met Lys
                 350                 355                 360

 Ser Cys Trp Arg Trp Arg Glu Ala Asp Arg Pro Ser Pro Arg Glu
                 365                 370                 375

 Leu Arg Leu Arg Leu Glu Ala Ala Ile Lys Thr Ala Asp Asp Glu
                 380                 385                 390

 Ala Val Leu Gln Val Pro Glu Leu Val Val Pro Glu Leu Tyr Ala
                 395                 400                 405

 Ala Val Ala Gly Ile Arg Val Glu Ser Leu Phe Tyr Asn Tyr Ser
                 410                 415                 420

 Met Leu


<210> 6154
<211> 1109
<212> DNA
<213> Homo sapien

<400> 6154
 actggaagac caggcagccc agctgaaggc agtaagctcg gctcacagtc 50

 gcaggagagt tctggggtac acgggcaaag gggcttgaga aggcccggag 100

 gcgaagccga agagaagcaa ctgtgccccg gagaagagaa gctcgcccat 150

 tccagactgg gaaccagctt tcagtgaaga tggcagggcc agaactgttg 200

 ctcgactcca acatccgcct ctgggtggtc ctacccatcg ttatcatcac 250

 tttcttcgta ggcatgatcc gccactacgt gtccatcctg ctgcagagcg 300

 acaagaagct cacccaggaa caagtatctg acagtcaagt cctaattcga 350

 agcagagtcc tcagggaaaa tggaaaatac attcccaaac agtctttctt 400

 gacacgaaaa tattatttca acaacccaga ggatggattt ttcaaaaaaa 450

 ctaaacggaa ggtagtgcca ccttctccta tgactgatcc tactatgttg 500

 acagacatga tgaaagggaa tgtaacaaat gtcctcccta tgattcttat 550

 tggtggatgg atcaacatga cattctcagg ctttgtcaca accaaggtcc 600

 catttccact gaccctccgt tttaagccta tgttacagca aggaatcgag 650

 ctactcacat tagatgcatc ctgggtgagt tctgcatcct ggtacttcct 700

 caatgtattt gggcttcgga gcatttactc tctgattctg ggccaagata 750

 atgccgctga ccaatcacga atgatgcagg agcagatgac gggagcagcc 800

 atggccatgc ccgcagacac aaacaaagct ttcaagacag agtgggaagc 850

 tttggagctg acggatcacc agtgggcact agatgatgtc gaagaagagc 900

 tcatggccaa agacctccac ttcgaaggca tgttcaaaaa ggaattacag 950

 acctctattt tttgaagacc gagcagggat tagctgtgtc aggaacttgg 1000

 agttgcactt aaccttgtaa ctttgtttgg agctggcacc tcttgaaata 1050

 aaaaggagga tgcacgagct ggcaggcatg caaaaaaaaa aaaaaaaaaa 1100

 aaaaaaaaa 1109

<210> 6155
<211> 261
<212> PRT
<213> Homo sapien

<400> 6155
 Met Ala Gly Pro Glu Leu Leu Leu Asp Ser Asn Ile Arg Leu Trp
   1               5                  10                  15

 Val Val Leu Pro Ile Val Ile Ile Thr Phe Phe Val Gly Met Ile
                  20                  25                  30

 Arg His Tyr Val Ser Ile Leu Leu Gln Ser Asp Lys Lys Leu Thr
                  35                  40                  45

 Gln Glu Gln Val Ser Asp Ser Gln Val Leu Ile Arg Ser Arg Val
                  50                  55                  60

 Leu Arg Glu Asn Gly Lys Tyr Ile Pro Lys Gln Ser Phe Leu Thr
                  65                  70                  75

 Arg Lys Tyr Tyr Phe Asn Asn Pro Glu Asp Gly Phe Phe Lys Lys
                  80                  85                  90

 Thr Lys Arg Lys Val Val Pro Pro Ser Pro Met Thr Asp Pro Thr
                  95                 100                 105

 Met Leu Thr Asp Met Met Lys Gly Asn Val Thr Asn Val Leu Pro
                 110                 115                 120

 Met Ile Leu Ile Gly Gly Trp Ile Asn Met Thr Phe Ser Gly Phe
                 125                 130                 135

 Val Thr Thr Lys Val Pro Phe Pro Leu Thr Leu Arg Phe Lys Pro
                 140                 145                 150

 Met Leu Gln Gln Gly Ile Glu Leu Leu Thr Leu Asp Ala Ser Trp
                 155                 160                 165

 Val Ser Ser Ala Ser Trp Tyr Phe Leu Asn Val Phe Gly Leu Arg
                 170                 175                 180

 Ser Ile Tyr Ser Leu Ile Leu Gly Gln Asp Asn Ala Ala Asp Gln
                 185                 190                 195

 Ser Arg Met Met Gln Glu Gln Met Thr Gly Ala Ala Met Ala Met
                 200                 205                 210

 Pro Ala Asp Thr Asn Lys Ala Phe Lys Thr Glu Trp Glu Ala Leu
                 215                 220                 225

 Glu Leu Thr Asp His Gln Trp Ala Leu Asp Asp Val Glu Glu Glu
                 230                 235                 240

 Leu Met Ala Lys Asp Leu His Phe Glu Gly Met Phe Lys Lys Glu
                 245                 250                 255

 Leu Gln Thr Ser Ile Phe
                 260

<210> 6156
<211> 2401
<212> DNA
<213> Homo sapien

<400> 6156
 gattggaagc agaggaagct gaagaaaagt aatgtagttt ccttaaaggc 50

 atacaaagga ctggcagaag tcgctgtgaa gagcttgtgt gagctgttgg 100

 tggcactacc tcattttaac tttcacaaca acatcatcgt attgattgtc 150

 cctctcatga atgacatgtc aaaattgata tctgaaatgt gttgtgaagc 200

 tgtgaagaaa ctctttaagc aagataaatt aggccaagct tctcttggtg 250

 taattaaagt gatttctggt tttgtgaagg gcagaaatta cgaagttagg 300

 ccagagatgt taaaaacatt tttatgccta agaatcaagg aagtagaagt 350

 gaaaaaagat acagaagaca ttaataaacc aaaaaaattt atgactttca 400

 aagaaaagag aaaatctcta tcaagaatgc agagaaagtg gaagaaagca 450

 gaagagaaac tagcgcgaga gcttcgagag gcagaagctt cagagagtac 500

 tgagaaaaaa cttaaactgc acacagagac tctgaatatt gtgtttgtaa 550

 cctacttcag aatattgaag aaggcccaga ggtcacctct cctgccagca 600

 gttctagaag gtcttgccaa gtttgctcac cttataaatg tggaattttt 650

 tgatgatctg ttagtagttc ttcatactct cattgagtct ggtgacctaa 700

 gctatcaaga aagtcttcac tgtgtccaga ctgcttttca tattctttct 750

 ggacaaggtg atgttctgaa tattgatcca ttgaaattct acacacatct 800

 ctacaaaaca ctgttcaaat tacatgcagg tgctaccaat gaaggtgttg 850

 agattgtact ccagtgcctt gatgtcatgc taactaagcg cagaaagcaa 900

 gtttctcagc agcgagctct tgccttcatc aaacgccttt gtacccttgc 950

 tcttcatgtt cttccaaatt caagtattgg cattttagca actaccagaa 1000

 tattaatgca tactttcccc aaaacagatc tactgcttga cagtgaatct 1050

 cagggaagtg gagttttcct tcctgaactg gatgagcctg agtactgcaa 1100

 tgctcagaac actgctctgt gggaactgca tgctctgcgg aggcattatc 1150

 atcccatagt gcagagattt gcagcccacc tgatcgctgg agcaccttct 1200

 gaaggctctg gagcactcaa accagagttg agtcgaagat ctgctactga 1250

 actttttgag gcatatagca tggcagaaat gacattcaat cctcctgttg 1300

 aatcttcaaa ccccaaaata aagggtaaat ttttacaagg ggattcattt 1350

 ttgaatgaag atttaaatca gctaatcaaa agatactcca gtgaagttgc 1400

 tactgaatcg cctctggatt tcacgaaata tttgaaaaca tcactacact 1450

 agtagaggaa tgaagtcagt ggactttctt gtatatttgt gtgtgcagat 1500

 gtacataaag atgagttgtt aacttaggat cttttctttt tatacaagga 1550

 aagcttccta agaatgtcta ggaagaagag gaagaatgac cctttgcatg 1600

 gcacagggtt ctgcccctat tctgaatatg tcattccatc aaggagatca 1650

 aaagcctttt tttctcccca gtatttggaa attactttct tgatgatgct 1700

 gccttttaaa agcttcacgt acattatagt tttttaaaaa aatctttgga 1750

 ctggatctta ctgaagtgca gttgctatat taaaattagg gcatagagca 1800

 cagaaaaatc aagaccatga gaagacattt taccatttag ctacttttta 1850

 taactaaata ctctttaaat atttttattt caatactgtg gatggaaatg 1900

 agaagcattc taaatttgag ttaatatatt tttatgaaga tatttgagaa 1950

 aagaaaaaaa tagcttgtat tcaggttcat tggcttttgc tggatgatcc 2000

 acctaaagaa gttacctaat ttggcctttt aaaaaaggtg ttagtgttta 2050

 ttatagctac tttcaaggaa agtttgaata tgattctagt ctctaaagtt 2100

 cttcacgttt tctgacattc cctggagggt gactggggaa gaattgctcc 2150

 agggtagaag aaccaggccc aagactttac cattctgatc tagagacaaa 2200

 ggatactcaa tgaggagctt ttttcccctc ttggaacagg taaaatgctt 2250

 tttcttatta atataattat aaaacagtat tttatgtaac agctattccc 2300

 atattctagg agtggcctaa gaaatgcgtg tttcagtgac tagattataa 2350

 atattctcta ttgtgaatag ttgaataaaa cagctgtttt tttctgcttc 2400

 t 2401

<210> 6157
<211> 431
<212> PRT
<213> Homo sapien

<400> 6157
 Met Asn Asp Met Ser Lys Leu Ile Ser Glu Met Cys Cys Glu Ala
   1               5                  10                  15

 Val Lys Lys Leu Phe Lys Gln Asp Lys Leu Gly Gln Ala Ser Leu
                  20                  25                  30

 Gly Val Ile Lys Val Ile Ser Gly Phe Val Lys Gly Arg Asn Tyr
                  35                  40                  45

 Glu Val Arg Pro Glu Met Leu Lys Thr Phe Leu Cys Leu Arg Ile
                  50                  55                  60

 Lys Glu Val Glu Val Lys Lys Asp Thr Glu Asp Ile Asn Lys Pro
                  65                  70                  75

 Lys Lys Phe Met Thr Phe Lys Glu Lys Arg Lys Ser Leu Ser Arg
                  80                  85                  90

 Met Gln Arg Lys Trp Lys Lys Ala Glu Glu Lys Leu Ala Arg Glu
                  95                 100                 105

 Leu Arg Glu Ala Glu Ala Ser Glu Ser Thr Glu Lys Lys Leu Lys
                 110                 115                 120

 Leu His Thr Glu Thr Leu Asn Ile Val Phe Val Thr Tyr Phe Arg
                 125                 130                 135

 Ile Leu Lys Lys Ala Gln Arg Ser Pro Leu Leu Pro Ala Val Leu
                 140                 145                 150

 Glu Gly Leu Ala Lys Phe Ala His Leu Ile Asn Val Glu Phe Phe
                 155                 160                 165

 Asp Asp Leu Leu Val Val Leu His Thr Leu Ile Glu Ser Gly Asp
                 170                 175                 180

 Leu Ser Tyr Gln Glu Ser Leu His Cys Val Gln Thr Ala Phe His
                 185                 190                 195

 Ile Leu Ser Gly Gln Gly Asp Val Leu Asn Ile Asp Pro Leu Lys
                 200                 205                 210

 Phe Tyr Thr His Leu Tyr Lys Thr Leu Phe Lys Leu His Ala Gly
                 215                 220                 225

 Ala Thr Asn Glu Gly Val Glu Ile Val Leu Gln Cys Leu Asp Val
                 230                 235                 240

 Met Leu Thr Lys Arg Arg Lys Gln Val Ser Gln Gln Arg Ala Leu
                 245                 250                 255

 Ala Phe Ile Lys Arg Leu Cys Thr Leu Ala Leu His Val Leu Pro
                 260                 265                 270

 Asn Ser Ser Ile Gly Ile Leu Ala Thr Thr Arg Ile Leu Met His
                 275                 280                 285

 Thr Phe Pro Lys Thr Asp Leu Leu Leu Asp Ser Glu Ser Gln Gly
                 290                 295                 300

 Ser Gly Val Phe Leu Pro Glu Leu Asp Glu Pro Glu Tyr Cys Asn
                 305                 310                 315

 Ala Gln Asn Thr Ala Leu Trp Glu Leu His Ala Leu Arg Arg His
                 320                 325                 330

 Tyr His Pro Ile Val Gln Arg Phe Ala Ala His Leu Ile Ala Gly
                 335                 340                 345

 Ala Pro Ser Glu Gly Ser Gly Ala Leu Lys Pro Glu Leu Ser Arg
                 350                 355                 360

 Arg Ser Ala Thr Glu Leu Phe Glu Ala Tyr Ser Met Ala Glu Met
                 365                 370                 375

 Thr Phe Asn Pro Pro Val Glu Ser Ser Asn Pro Lys Ile Lys Gly
                 380                 385                 390

 Lys Phe Leu Gln Gly Asp Ser Phe Leu Asn Glu Asp Leu Asn Gln
                 395                 400                 405

 Leu Ile Lys Arg Tyr Ser Ser Glu Val Ala Thr Glu Ser Pro Leu
                 410                 415                 420

 Asp Phe Thr Lys Tyr Leu Lys Thr Ser Leu His
                 425                 430

<210> 6158
<211> 1931
<212> DNA
<213> Homo sapien

<400> 6158
 ggctcgggct ccggctcggg ctcccgcggc gtgggctggg cagcagccgg 50

 gcggcggctc cgcggcgccg ggcaggggcc gtccgcgggt ccgcgccctc 100

 gggcggcggc gtctcctggg tcccggcagc cgtccgcgcg cccgggcgca 150

 ggtttggttt tcctaaacaa atcctttcac agggaccgac ggcacttgat 200

 aatgtgacaa aaaccagcct cttccacccc actgcagtga cttttgccgg 250

 aaagtggagc agtgggcacg gccaaccttg tcgttcatca atgccgcccc 300

 tggcagtatc tgaggatcgg tggcagccat gcctccccct gccccagccg 350

 ctccttcccc cccacgctaa tctgcatggt gtgggcgccc ttgggacccc 400

 cgaggactga ttgtctgacc ttgcttcaca cgcccagtaa ggactccccc 450

 aagatgtcgc tcgagtggct ggtggcctgg agctggtcgc tggatggcct 500

 gagggactgc atcgccaccg gcatccagtc cgtgcgggac tgcgacacca 550

 ccgctgtcat cactgtggcc tgcctcctgg tcctcttcgt gtggtactgt 600

 tatcacgtgg gcagggagca gccccggccc tacgtctccg tcaactccct 650

 catgcaggct gccgatgcca acgggctgca gaatggctac gtgtactgcc 700

 agtcccctga gtgcgtgcgc tgcacccaca acgagggcct caaccagaag 750

 ctgtaccaca acctgcagga gtacgccaag cgctactcct ggtccggcat 800

 gggccgcatc cacaagggca tccgcgagca gggccggtac ctcaacagcc 850

 ggccctccat ccagaagccc gaggtcttct tcctgcccga cctgcccacc 900

 acgccctatt tctcccggga cgcacagaaa catgatgtgg aagtgctgga 950

 acggaacttc cagaccatcc tgtgtgagtt tgagaccctc tacaaagctt 1000

 tctcaaactg cagcctcccg caaggatgga aaatgaacag cacccccagc 1050

 ggggagtggt tcacctttta cttggtcaat cagggggttt gtgttcccag 1100

 gaactgtagg aagtgcccac ggacgtaccg cttgctcgga agccttcgga 1150

 cctgtattgg gaacaatgtt tttgggaacg cgtgcatctc tgtgctgagc 1200

 cctgggactg tgataacgga gcactatgga cccaccaaca tccgcatccg 1250

 atgccattta ggtctgaaaa ctccaaatgg ctgtgagctg gtggtggggg 1300

 gagagcccca gtgctgggca gaagggcgct gccttctctt tgatgactct 1350

 ttcctgcatg ctgcgttcca tgaaggttca gcagaggatg gcccacgggt 1400

 ggttttcatg gtggatttgt ggcatccaaa cgtcgcagcg gccgaacggc 1450

 aggctcttga tttcatcttt gctccgggac gatgagagta tttcccatgc 1500

 tggagtcggc gagaagggcc gaggcggggc ctgggcagac tgtggtccgg 1550

 tccagtccct accggtgttg tttccatgct cagaaacctg cctcagcgga 1600

 aagctcttat ttgggatttt atatcatgtc gggtccctct ttcccttggt 1650

 tattgtaaat ggaaactttt cggcttgtat ttccttagat tttttttttt 1700

 tccttccaat catttgcttc agagactcct ttctggccta acagcgcatt 1750

 cctttgattg gtccttgagt gaccagagac ttagtgccct tgtaagtctg 1800

 tcttctgttg ctacttgttt ttttcagtgc tctgaaatag agtaactaaa 1850

 tggttatttg tctgaatata ataatgtaaa acttaaaaaa aaaaaaaaaa 1900

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1931

<210> 6159
<211> 343
<212> PRT
<213> Homo sapien

<400> 6159
 Met Ser Leu Glu Trp Leu Val Ala Trp Ser Trp Ser Leu Asp Gly
   1               5                  10                  15

 Leu Arg Asp Cys Ile Ala Thr Gly Ile Gln Ser Val Arg Asp Cys
                  20                  25                  30

 Asp Thr Thr Ala Val Ile Thr Val Ala Cys Leu Leu Val Leu Phe
                  35                  40                  45

 Val Trp Tyr Cys Tyr His Val Gly Arg Glu Gln Pro Arg Pro Tyr
                  50                  55                  60

 Val Ser Val Asn Ser Leu Met Gln Ala Ala Asp Ala Asn Gly Leu
                  65                  70                  75

 Gln Asn Gly Tyr Val Tyr Cys Gln Ser Pro Glu Cys Val Arg Cys
                  80                  85                  90

 Thr His Asn Glu Gly Leu Asn Gln Lys Leu Tyr His Asn Leu Gln
                  95                 100                 105

 Glu Tyr Ala Lys Arg Tyr Ser Trp Ser Gly Met Gly Arg Ile His
                 110                 115                 120

 Lys Gly Ile Arg Glu Gln Gly Arg Tyr Leu Asn Ser Arg Pro Ser
                 125                 130                 135

 Ile Gln Lys Pro Glu Val Phe Phe Leu Pro Asp Leu Pro Thr Thr
                 140                 145                 150

 Pro Tyr Phe Ser Arg Asp Ala Gln Lys His Asp Val Glu Val Leu
                 155                 160                 165

 Glu Arg Asn Phe Gln Thr Ile Leu Cys Glu Phe Glu Thr Leu Tyr
                 170                 175                 180

 Lys Ala Phe Ser Asn Cys Ser Leu Pro Gln Gly Trp Lys Met Asn
                 185                 190                 195

 Ser Thr Pro Ser Gly Glu Trp Phe Thr Phe Tyr Leu Val Asn Gln
                 200                 205                 210

 Gly Val Cys Val Pro Arg Asn Cys Arg Lys Cys Pro Arg Thr Tyr
                 215                 220                 225

 Arg Leu Leu Gly Ser Leu Arg Thr Cys Ile Gly Asn Asn Val Phe
                 230                 235                 240

 Gly Asn Ala Cys Ile Ser Val Leu Ser Pro Gly Thr Val Ile Thr
                 245                 250                 255

 Glu His Tyr Gly Pro Thr Asn Ile Arg Ile Arg Cys His Leu Gly
                 260                 265                 270

 Leu Lys Thr Pro Asn Gly Cys Glu Leu Val Val Gly Gly Glu Pro
                 275                 280                 285

 Gln Cys Trp Ala Glu Gly Arg Cys Leu Leu Phe Asp Asp Ser Phe
                 290                 295                 300

 Leu His Ala Ala Phe His Glu Gly Ser Ala Glu Asp Gly Pro Arg
                 305                 310                 315

 Val Val Phe Met Val Asp Leu Trp His Pro Asn Val Ala Ala Ala
                 320                 325                 330

 Glu Arg Gln Ala Leu Asp Phe Ile Phe Ala Pro Gly Arg
                 335                 340

<210> 6160
<211> 1668
<212> DNA
<213> Homo sapien

<400> 6160
 atggcagccc gtctgctcct cctgggcatc cttctcctgc tgctgcccct 50

 gcccgtccct gccccgtgcc acacagccgc acgctcagag tgcaagcgca 100

 gccacaagtt cgtgcctggt gcatggctgg ccggggaggg tgtggacgtg 150

 accagcctcc gccgctcggg ctccttccca gtggacacac aaaggttcct 200

 gcggcccgac ggcacctgca ccctctgtga aaatgcccta caggagggca 250

 ccctccagcg cctgcctctg gcgctcacca actggcgggc ccagggctct 300

 ggctgccagc gccatgtaac cagggccaaa gtcagctcca ctgaagctgt 350

 ggcccgggat gcggctcgta gcatccgcaa cgactggaag gtcgggctgg 400

 acgtgactcc taagcccacc agcaatgtgc atgtgtctgt ggccggctca 450

 cactcacagg cagccaactt tgcagcccag aagacccacc aggaccagta 500

 cagcttcagc actgacacgg tggagtgccg cttctacagt ttccatgtgg 550

 tacacactcc cccgctgcac cctgacttca agagggccct cggggacctg 600

 ccccaccact tcaacgcctc cacccagccc gcctacctca ggcttatctc 650

 caactacggc acccacttca tccgggctgt ggagctgggt ggccgcatat 700

 cggccctcac tgccctgcgc acctgcgagc tggccctgga agggctcacg 750

 gacaacgagg tggaggactg cctgactgtc gaggcccagg tcaacatagg 800

 catccacggc agcatctctg ccgaagccaa ggcctgtgag gagaagaaga 850

 agaagcacaa gatgacggcc tccttccacc aaacctaccg ggagcgccac 900

 tcggaagtgg ttggcggcca tcacacctcc attaacgacc tgctgttcgg 950

 gatccaggcc gggcccgagc agtactcagc ctgggtaaac tccgtgcccg 1000

 gcagccctgg cctggtggac tacaccctgg aacccctgca cgtgctgctg 1050

 gacagccagg acccgcggcg ggaggcactg aggagggccc tgagtcagta 1100

 cctgacggac agggctcgct ggagggactg cagccggccg tgcccaccag 1150

 ggcggcagaa gagcccccga gacccatgcc agtgtgtgtg ccatggctca 1200

 gcggtcacca cccaggactg ctgccctcgg cagaggggcc tggcccagct 1250

 ggaggtgacc ttcatccaag catggagcct gtggggggac tggttcactg 1300

 ccacggatgc ctatgtgaag ctcttctttg gtggccagga gctgaggacg 1350

 agcaccgtgt gggacaataa caaccccatc tggtcagtgc ggctggattt 1400

 tggggatgtg ctcctggcca caggggggcc cctgaggttg caggtctggg 1450

 atcaggactc tggcagggac gatgacctcc ttggcacctg tgatcaggct 1500

 cccaagtctg gttcccatga ggtgagatgc aacctgaatc atggccacct 1550

 aaaattccgc tatcatgcca ggtgcttgcc ccacctggga ggaggcacct 1600

 gcctggacta tgtcccccaa atgcttctgg gggagcctcc aggaaaccgg 1650

 agtggggccg tgtggtga 1668

<210> 6161
<211> 555
<212> PRT
<213> Homo sapien

<400> 6161
 Met Ala Ala Arg Leu Leu Leu Leu Gly Ile Leu Leu Leu Leu Leu
   1               5                  10                  15

 Pro Leu Pro Val Pro Ala Pro Cys His Thr Ala Ala Arg Ser Glu
                  20                  25                  30

 Cys Lys Arg Ser His Lys Phe Val Pro Gly Ala Trp Leu Ala Gly
                  35                  40                  45

 Glu Gly Val Asp Val Thr Ser Leu Arg Arg Ser Gly Ser Phe Pro
                  50                  55                  60

 Val Asp Thr Gln Arg Phe Leu Arg Pro Asp Gly Thr Cys Thr Leu
                  65                  70                  75

 Cys Glu Asn Ala Leu Gln Glu Gly Thr Leu Gln Arg Leu Pro Leu
                  80                  85                  90

 Ala Leu Thr Asn Trp Arg Ala Gln Gly Ser Gly Cys Gln Arg His
                  95                 100                 105

 Val Thr Arg Ala Lys Val Ser Ser Thr Glu Ala Val Ala Arg Asp
                 110                 115                 120

 Ala Ala Arg Ser Ile Arg Asn Asp Trp Lys Val Gly Leu Asp Val
                 125                 130                 135

 Thr Pro Lys Pro Thr Ser Asn Val His Val Ser Val Ala Gly Ser
                 140                 145                 150

 His Ser Gln Ala Ala Asn Phe Ala Ala Gln Lys Thr His Gln Asp
                 155                 160                 165

 Gln Tyr Ser Phe Ser Thr Asp Thr Val Glu Cys Arg Phe Tyr Ser
                 170                 175                 180

 Phe His Val Val His Thr Pro Pro Leu His Pro Asp Phe Lys Arg
                 185                 190                 195

 Ala Leu Gly Asp Leu Pro His His Phe Asn Ala Ser Thr Gln Pro
                 200                 205                 210

 Ala Tyr Leu Arg Leu Ile Ser Asn Tyr Gly Thr His Phe Ile Arg
                 215                 220                 225

 Ala Val Glu Leu Gly Gly Arg Ile Ser Ala Leu Thr Ala Leu Arg
                 230                 235                 240

 Thr Cys Glu Leu Ala Leu Glu Gly Leu Thr Asp Asn Glu Val Glu
                 245                 250                 255

 Asp Cys Leu Thr Val Glu Ala Gln Val Asn Ile Gly Ile His Gly
                 260                 265                 270

 Ser Ile Ser Ala Glu Ala Lys Ala Cys Glu Glu Lys Lys Lys Lys
                 275                 280                 285

 His Lys Met Thr Ala Ser Phe His Gln Thr Tyr Arg Glu Arg His
                 290                 295                 300

 Ser Glu Val Val Gly Gly His His Thr Ser Ile Asn Asp Leu Leu
                 305                 310                 315

 Phe Gly Ile Gln Ala Gly Pro Glu Gln Tyr Ser Ala Trp Val Asn
                 320                 325                 330

 Ser Val Pro Gly Ser Pro Gly Leu Val Asp Tyr Thr Leu Glu Pro
                 335                 340                 345

 Leu His Val Leu Leu Asp Ser Gln Asp Pro Arg Arg Glu Ala Leu
                 350                 355                 360

 Arg Arg Ala Leu Ser Gln Tyr Leu Thr Asp Arg Ala Arg Trp Arg
                 365                 370                 375

 Asp Cys Ser Arg Pro Cys Pro Pro Gly Arg Gln Lys Ser Pro Arg
                 380                 385                 390

 Asp Pro Cys Gln Cys Val Cys His Gly Ser Ala Val Thr Thr Gln
                 395                 400                 405

 Asp Cys Cys Pro Arg Gln Arg Gly Leu Ala Gln Leu Glu Val Thr
                 410                 415                 420

 Phe Ile Gln Ala Trp Ser Leu Trp Gly Asp Trp Phe Thr Ala Thr
                 425                 430                 435

 Asp Ala Tyr Val Lys Leu Phe Phe Gly Gly Gln Glu Leu Arg Thr
                 440                 445                 450

 Ser Thr Val Trp Asp Asn Asn Asn Pro Ile Trp Ser Val Arg Leu
                 455                 460                 465

 Asp Phe Gly Asp Val Leu Leu Ala Thr Gly Gly Pro Leu Arg Leu
                 470                 475                 480

 Gln Val Trp Asp Gln Asp Ser Gly Arg Asp Asp Asp Leu Leu Gly
                 485                 490                 495

 Thr Cys Asp Gln Ala Pro Lys Ser Gly Ser His Glu Val Arg Cys
                 500                 505                 510

 Asn Leu Asn His Gly His Leu Lys Phe Arg Tyr His Ala Arg Cys
                 515                 520                 525

 Leu Pro His Leu Gly Gly Gly Thr Cys Leu Asp Tyr Val Pro Gln
                 530                 535                 540

 Met Leu Leu Gly Glu Pro Pro Gly Asn Arg Ser Gly Ala Val Trp
                 545                 550                 555

<210> 6162
<211> 3297
<212> DNA
<213> Homo sapien

<400> 6162
 cagggtctcc cccactaaac cgtgcgggtg ccaggggacg aaagaagtgc 50

 aaaagcgcgg gcttggaggg gatggcttgt gttaagttgc tttgctccca 100

 tcagaatcga ggagacgtgg cgcctgtggc agaagttttt agacgactat 150

 tctcgctttg aggactggct caagtcagct gagaggacgg cagcctgccc 200

 aaattcctca gaggtgttgt acacgagtgc caaagaggaa ctgaagaggt 250

 ttgaggcctt tcagcggcag attcatgagc ggctcactca gctggagctc 300

 atcaacaagc agtaccggcg gctggcccgg gagaaccgca cagacacggc 350

 cagcaggctg aagcagatgg tccacgaggg caaccagcgc tgggacaacc 400

 ttcagaggcg ggtcacagcc gtcctgcgga gactcaggca tttcaccaac 450

 cagagggaag aatttgaggg caccagggag agcattctgg tgtggctcac 500

 agagatggac ctgcagctga ccaacgtgga gcacttctca gagagtgacg 550

 ccgatgacaa gatgcgccaa ctgaatggct tccaacagga aattacatta 600

 aataccaaca agattgatca gctcattgtg tttggggagc agctgattca 650

 gaagagcgag cccctggatg ctgtgctgat tgaggatgag ctggaggaac 700

 tccaccgcta ctgccaggag gtgtttggaa gggtctcccg gttccaccgg 750

 cggctcacct cctgcactcc gggcttggaa gatgaaaagg aggcctctga 800

 gaatgaaaca gacatggaag accccagaga aatccagact gattcttggc 850

 gtaaacgggg agagagcgag gaaccgtcat ctcctcagtc cctgtgtcat 900

 ctagtggccc cagggcacga gcggtctggc tgcgagaccc ctgtcagcgt 950

 ggactccatc cccctggagt gggaccacac aggcgacgtg gggggctcct 1000

 cctctcacga agaggacgag gagggcccat actacagcgc actgtcaggt 1050

 aaatccattt cggatggcca ctcgtggcat gttcccgaca gcccttcctg 1100

 tcccgagcat cactacaagc aaatggaagg tgacaggaat gttccacctg 1150

 ttccccctgc gtccagcacc ccttataaac caccctatgg aaagctacta 1200

 ttacctccag gcacggatgg tggcaaagaa ggcccgcgag tcctgaatgg 1250

 caacccacag caggaagacg ggggactggc cggtatcaca gagcagcagt 1300

 caggtgcctt cgacagatgg gagatgattc aagcacagga gcttcacaat 1350

 aagctcaaaa taaaacaaaa tttgcaacag ctgaactctg atatcagcgc 1400

 catcactact tggctgaaaa aaactgaagc agagctggaa atgttaaaga 1450

 tggcaaagcc tccctctgat atccaggaaa tagaactgag agtgaagaga 1500

 ctgcaggaga tactgaaagc ctttgacact tacaaggcat tagtggtctc 1550

 tgtcaacgtg agcagcaagg aatttctgca aaccgagagc cccgaatcca 1600

 cagagctcca aagtagactc cgccagctga gcctgctctg ggaagcagca 1650

 cagggcgcag tggacagctg gagagggggc ttacgacagt cgctcatgca 1700

 gtgccaggac ttccaccagt tgagtcaaaa tctgctgctg tggttagcga 1750

 gtgccaagaa ccggaggcag aaggctcatg tcaccgatcc aaaggcagac 1800

 ccccgggctc tcctagagtg tcggagggaa ctaatgcaac tggaaaagga 1850

 gctggtagaa cgtcaacctc aagtggacat gttacaggag atttcaaaca 1900

 gccttctcat taagggacat ggagaagact gtattgaagc tgaagaaaag 1950

 gtgcatgtta ttgagaagaa actcaaacag ttacgggagc aagtgtccca 2000

 agatttaatg gccttgcagg gaacccagaa cccagcctca cccctgccca 2050

 gcttcgacga ggtagactcg ggggaccagc ctcctgcaac atccgtgcca 2100

 gctccccgag caaagcagtt cagagcagtg agaactacag aaggcgagga 2150

 ggagacagag agcagggtcc ccggcagcac acggccacag cgctccttcc 2200

 tctcaagggt ggtccgggca gccctacccc tgcagctgct cctcctgctg 2250

 ctgctgctcc tggcctgcct gctgccctcc tccgaagaag actacagctg 2300

 cactcaggcc aacaactttg cccggtcctt ttaccccatg ctgaggtaca 2350

 ccaatgggcc accccccaca tagagggcat agctggccac agtgctacac 2400

 cacctgcctg attgccaagg gtgcccagca cgtggcccca gaccaatctg 2450

 agtgacttag tgttggcaag gtcccgggac ctgtgcagac ttcttctggg 2500

 cttacacagc acgggctccc tggagcccag ggcagctttc agattgtgtt 2550

 cctccccagg agcagggaac ctgtgtggca ggtgccccgg gtactttggc 2600

 agaactagtt gattagttta gggatctctg gaaatgtcag tttcctgaag 2650

 agccaagcac tttgtgaatt ctggtttgtt tgtaaaacag cattattata 2700

 atgtaggtat ggtcaatgag cagtggtgtc catcacatat attatagaag 2750

 caagcgagca cattccaccc tagaaatggt tcagaaactc ataggcaccc 2800

 ttagctgatg gaaacaatca atcatattta atacgcttag aatcagtttt 2850

 actccaatca gctggcaatt ttgagctgcc ggttatacac caaaatgttc 2900

 tgttcagtac ctagctctgc tcttttatat tgctttaaat ttttaaagaa 2950

 attatattgc atggatgtgg ttatttgtgc atatttttta acaatgccca 3000

 atctgtatga ataatgtaaa cttcgatttt tttttaaaaa aattagattt 3050

 tagctggagc ttttgactaa tgtaaagtaa atgccaaact accgacttga 3100

 tagggatgtt tttgtaagtt aattttctaa gactttttca catccaaagt 3150

 gatgctttgc tttgggtttt aactgtttgg ccacggcggg ggtgggggcg 3200

 gggggttggt acagaaactt gaagctgttt gtgatatgta caactcagat 3250

 gtttctcatt aaaaaacaaa attagccaga aaaaaaaaaa aaaaaaa 3297

<210> 6163
<211> 668
<212> PRT
<213> Homo sapien

<400> 6163
 Met Val His Glu Gly Asn Gln Arg Trp Asp Asn Leu Gln Arg Arg
   1               5                  10                  15

 Val Thr Ala Val Leu Arg Arg Leu Arg His Phe Thr Asn Gln Arg
                  20                  25                  30

 Glu Glu Phe Glu Gly Thr Arg Glu Ser Ile Leu Val Trp Leu Thr
                  35                  40                  45

 Glu Met Asp Leu Gln Leu Thr Asn Val Glu His Phe Ser Glu Ser
                  50                  55                  60

 Asp Ala Asp Asp Lys Met Arg Gln Leu Asn Gly Phe Gln Gln Glu
                  65                  70                  75

 Ile Thr Leu Asn Thr Asn Lys Ile Asp Gln Leu Ile Val Phe Gly
                  80                  85                  90

 Glu Gln Leu Ile Gln Lys Ser Glu Pro Leu Asp Ala Val Leu Ile
                  95                 100                 105

 Glu Asp Glu Leu Glu Glu Leu His Arg Tyr Cys Gln Glu Val Phe
                 110                 115                 120

 Gly Arg Val Ser Arg Phe His Arg Arg Leu Thr Ser Cys Thr Pro
                 125                 130                 135

 Gly Leu Glu Asp Glu Lys Glu Ala Ser Glu Asn Glu Thr Asp Met
                 140                 145                 150

 Glu Asp Pro Arg Glu Ile Gln Thr Asp Ser Trp Arg Lys Arg Gly
                 155                 160                 165

 Glu Ser Glu Glu Pro Ser Ser Pro Gln Ser Leu Cys His Leu Val
                 170                 175                 180

 Ala Pro Gly His Glu Arg Ser Gly Cys Glu Thr Pro Val Ser Val
                 185                 190                 195

 Asp Ser Ile Pro Leu Glu Trp Asp His Thr Gly Asp Val Gly Gly
                 200                 205                 210

 Ser Ser Ser His Glu Glu Asp Glu Glu Gly Pro Tyr Tyr Ser Ala
                 215                 220                 225

 Leu Ser Gly Lys Ser Ile Ser Asp Gly His Ser Trp His Val Pro
                 230                 235                 240

 Asp Ser Pro Ser Cys Pro Glu His His Tyr Lys Gln Met Glu Gly
                 245                 250                 255

 Asp Arg Asn Val Pro Pro Val Pro Pro Ala Ser Ser Thr Pro Tyr
                 260                 265                 270

 Lys Pro Pro Tyr Gly Lys Leu Leu Leu Pro Pro Gly Thr Asp Gly
                 275                 280                 285

 Gly Lys Glu Gly Pro Arg Val Leu Asn Gly Asn Pro Gln Gln Glu
                 290                 295                 300

 Asp Gly Gly Leu Ala Gly Ile Thr Glu Gln Gln Ser Gly Ala Phe
                 305                 310                 315

 Asp Arg Trp Glu Met Ile Gln Ala Gln Glu Leu His Asn Lys Leu
                 320                 325                 330

 Lys Ile Lys Gln Asn Leu Gln Gln Leu Asn Ser Asp Ile Ser Ala
                 335                 340                 345

 Ile Thr Thr Trp Leu Lys Lys Thr Glu Ala Glu Leu Glu Met Leu
                 350                 355                 360

 Lys Met Ala Lys Pro Pro Ser Asp Ile Gln Glu Ile Glu Leu Arg
                 365                 370                 375

 Val Lys Arg Leu Gln Glu Ile Leu Lys Ala Phe Asp Thr Tyr Lys
                 380                 385                 390

 Ala Leu Val Val Ser Val Asn Val Ser Ser Lys Glu Phe Leu Gln
                 395                 400                 405

 Thr Glu Ser Pro Glu Ser Thr Glu Leu Gln Ser Arg Leu Arg Gln
                 410                 415                 420

 Leu Ser Leu Leu Trp Glu Ala Ala Gln Gly Ala Val Asp Ser Trp
                 425                 430                 435

 Arg Gly Gly Leu Arg Gln Ser Leu Met Gln Cys Gln Asp Phe His
                 440                 445                 450

 Gln Leu Ser Gln Asn Leu Leu Leu Trp Leu Ala Ser Ala Lys Asn
                 455                 460                 465

 Arg Arg Gln Lys Ala His Val Thr Asp Pro Lys Ala Asp Pro Arg
                 470                 475                 480

 Ala Leu Leu Glu Cys Arg Arg Glu Leu Met Gln Leu Glu Lys Glu
                 485                 490                 495

 Leu Val Glu Arg Gln Pro Gln Val Asp Met Leu Gln Glu Ile Ser
                 500                 505                 510

 Asn Ser Leu Leu Ile Lys Gly His Gly Glu Asp Cys Ile Glu Ala
                 515                 520                 525

 Glu Glu Lys Val His Val Ile Glu Lys Lys Leu Lys Gln Leu Arg
                 530                 535                 540

 Glu Gln Val Ser Gln Asp Leu Met Ala Leu Gln Gly Thr Gln Asn
                 545                 550                 555

 Pro Ala Ser Pro Leu Pro Ser Phe Asp Glu Val Asp Ser Gly Asp
                 560                 565                 570

 Gln Pro Pro Ala Thr Ser Val Pro Ala Pro Arg Ala Lys Gln Phe
                 575                 580                 585

 Arg Ala Val Arg Thr Thr Glu Gly Glu Glu Glu Thr Glu Ser Arg
                 590                 595                 600

 Val Pro Gly Ser Thr Arg Pro Gln Arg Ser Phe Leu Ser Arg Val
                 605                 610                 615

 Val Arg Ala Ala Leu Pro Leu Gln Leu Leu Leu Leu Leu Leu Leu
                 620                 625                 630

 Leu Leu Ala Cys Leu Leu Pro Ser Ser Glu Glu Asp Tyr Ser Cys
                 635                 640                 645

 Thr Gln Ala Asn Asn Phe Ala Arg Ser Phe Tyr Pro Met Leu Arg
                 650                 655                 660

 Tyr Thr Asn Gly Pro Pro Pro Thr
                 665

<210> 6164
<211> 983
<212> DNA
<213> Homo sapien

<400> 6164
 ggcacgaggc ctgacatgga gcctgccagc tccgtcagcc ctgactcggc 50

 ccggagctga gctccccacc tgccggtagc ccaggagatg gagcagccca 100

 gcccacgtgc ccggccttcc gcccctgact tcacttgata acaaactaga 150

 aactgaaaca gggtcgggat gccgatgccg gcttggagtt agagatgagt 200

 caccgctgag agcagctgca gtagctgagc agtggcagca gagaggcaga 250

 cgtgagctga gggcgcagag gcaggcagca tctctgaggg tccccaagga 300

 gcatggctgg gagccgtgag gtggtggcca tggactgcga gatggtgggg 350

 ctggggcccc accgggagag tggcctggct cgttgcagcc tcgtgaacgt 400

 ccacggtgct gtgctgtacg acaagttcat ccggcctgag ggagagatca 450

 ccgattacag aacccgggtc agcggggtca cccctcagca catggtgggg 500

 gccacaccat ttgccgtggc caggctagag atcctgcagc tcctgaaagg 550

 caagctggtg gtgggtcatg acctgaagca cgacttccag gcactgaaag 600

 aggacatgag cggctacaca atctacgaca cgtccactga caggctgttg 650

 tggcgtgagg ccaagctgga ccactgcagg cgtgtctccc tgcgggtgct 700

 gagtgagcgc ctcctgcaca agagcatcca gaacagcctg cttggacaca 750

 gctcggtgga agatgcgagg gcaacgatgg agctctatca aatctcccag 800

 agaatccgag cccgccgagg gctgccccgc ctggctgtgt cagactgaag 850

 ccccatccag cccgttccgc agggactaga ggctttcggc tttttgggac 900

 agcaactacc ttgcttttgg aaaatacatt tttaatagta aagtggctct 950

 atattttctc tacgcaaaaa aaaaaaaaaa aaa 983

<210> 6165
<211> 181
<212> PRT
<213> Homo sapien

<400> 6165
 Met Ala Gly Ser Arg Glu Val Val Ala Met Asp Cys Glu Met Val
   1               5                  10                  15

 Gly Leu Gly Pro His Arg Glu Ser Gly Leu Ala Arg Cys Ser Leu
                  20                  25                  30

 Val Asn Val His Gly Ala Val Leu Tyr Asp Lys Phe Ile Arg Pro
                  35                  40                  45

 Glu Gly Glu Ile Thr Asp Tyr Arg Thr Arg Val Ser Gly Val Thr
                  50                  55                  60

 Pro Gln His Met Val Gly Ala Thr Pro Phe Ala Val Ala Arg Leu
                  65                  70                  75

 Glu Ile Leu Gln Leu Leu Lys Gly Lys Leu Val Val Gly His Asp
                  80                  85                  90

 Leu Lys His Asp Phe Gln Ala Leu Lys Glu Asp Met Ser Gly Tyr
                  95                 100                 105

 Thr Ile Tyr Asp Thr Ser Thr Asp Arg Leu Leu Trp Arg Glu Ala
                 110                 115                 120

 Lys Leu Asp His Cys Arg Arg Val Ser Leu Arg Val Leu Ser Glu
                 125                 130                 135

 Arg Leu Leu His Lys Ser Ile Gln Asn Ser Leu Leu Gly His Ser
                 140                 145                 150

 Ser Val Glu Asp Ala Arg Ala Thr Met Glu Leu Tyr Gln Ile Ser
                 155                 160                 165

 Gln Arg Ile Arg Ala Arg Arg Gly Leu Pro Arg Leu Ala Val Ser
                 170                 175                 180

 Asp


<210> 6166
<211> 1247
<212> DNA
<213> Homo sapien

<400> 6166
 gtaaagctag accgatctcc ggggagcccc ggagtaggcg agcggcggcc 50

 gccagctagt tgagcgcacc ccccgcccgc cccagcggcg ccgcggcggg 100

 cggcgtccag gcggcatgga gaaggacggc ctgtgccgcg ctgaccagca 150

 gtacgaatgc gtggcggaga tcggggaggg cgcctatggg aaggtgttca 200

 aggcccgcga cttgaagaac ggaggccgtt tcgtggcgtt gaagcgcgtg 250

 cgggtgcaga ccggcgagga gggcatgccg ctctccacca tccgcgaggt 300

 ggcggtgctg aggcacctgg agaccttcga gcaccccaac gtggtcaggt 350

 tgtttgatgt gtgcacagtg tcacgaacag acagagaaac caaactaact 400

 ttagtgtttg aacatgtcga tcaagacttg accacttact tggataaagt 450

 tccagagcct ggagtgccca ctgaaaccat aaaggatatg atgtttcagc 500

 ttctccgagg tctggacttt cttcattcac accgagtagt gcatcgcgat 550

 ctaaaaccac agaacattct ggtgaccagc agcggacaaa taaaactcgc 600

 tgacttcggc cttgcccgca tctatagttt ccagatggct ctaacctcag 650

 tggtcgtcac gctgtggtac agagcacccg aagtcttgct ccagtccagc 700

 tacgccaccc ccgtggatct ctggagtgtt ggctgcatat ttgcagaaat 750

 gtttcgtaga aagcctcttt ttcgtggaag ttcagatgtt gatcaactag 800

 gaaaaatctt ggacgtgatt ggactcccag gagaagaaga ctggcctaga 850

 gatgttgccc ttcccaggca ggcttttcat tcaaaatctg cccaaccaat 900

 tgagaagttt gtaacagata tcgatgaact aggcaaagac ctacttctga 950

 agtgtttgac atttaaccca gccaaaagaa tatctgccta cagtgccctg 1000

 tctcacccat acttccagga cctggaaagg tgcaaagaaa acctggattc 1050

 ccacctgccg cccagccaga acacctcgga gctgaataca gcctgaggcc 1100

 tcagcagccg ccttaagctg atcctgcgga gaacaccctt ggtggcttat 1150

 gggtccccct cagcaagccc tacagagctg tggaggattg ctatctggag 1200

 gccttccagc tgctgtcttc tggacaggct ctgcttctcc aaggaaa 1247

<210> 6167
<211> 326
<212> PRT
<213> Homo sapien

<400> 6167
 Met Glu Lys Asp Gly Leu Cys Arg Ala Asp Gln Gln Tyr Glu Cys
   1               5                  10                  15

 Val Ala Glu Ile Gly Glu Gly Ala Tyr Gly Lys Val Phe Lys Ala
                  20                  25                  30

 Arg Asp Leu Lys Asn Gly Gly Arg Phe Val Ala Leu Lys Arg Val
                  35                  40                  45

 Arg Val Gln Thr Gly Glu Glu Gly Met Pro Leu Ser Thr Ile Arg
                  50                  55                  60

 Glu Val Ala Val Leu Arg His Leu Glu Thr Phe Glu His Pro Asn
                  65                  70                  75

 Val Val Arg Leu Phe Asp Val Cys Thr Val Ser Arg Thr Asp Arg
                  80                  85                  90

 Glu Thr Lys Leu Thr Leu Val Phe Glu His Val Asp Gln Asp Leu
                  95                 100                 105

 Thr Thr Tyr Leu Asp Lys Val Pro Glu Pro Gly Val Pro Thr Glu
                 110                 115                 120

 Thr Ile Lys Asp Met Met Phe Gln Leu Leu Arg Gly Leu Asp Phe
                 125                 130                 135

 Leu His Ser His Arg Val Val His Arg Asp Leu Lys Pro Gln Asn
                 140                 145                 150

 Ile Leu Val Thr Ser Ser Gly Gln Ile Lys Leu Ala Asp Phe Gly
                 155                 160                 165

 Leu Ala Arg Ile Tyr Ser Phe Gln Met Ala Leu Thr Ser Val Val
                 170                 175                 180

 Val Thr Leu Trp Tyr Arg Ala Pro Glu Val Leu Leu Gln Ser Ser
                 185                 190                 195

 Tyr Ala Thr Pro Val Asp Leu Trp Ser Val Gly Cys Ile Phe Ala
                 200                 205                 210

 Glu Met Phe Arg Arg Lys Pro Leu Phe Arg Gly Ser Ser Asp Val
                 215                 220                 225

 Asp Gln Leu Gly Lys Ile Leu Asp Val Ile Gly Leu Pro Gly Glu
                 230                 235                 240

 Glu Asp Trp Pro Arg Asp Val Ala Leu Pro Arg Gln Ala Phe His
                 245                 250                 255

 Ser Lys Ser Ala Gln Pro Ile Glu Lys Phe Val Thr Asp Ile Asp
                 260                 265                 270

 Glu Leu Gly Lys Asp Leu Leu Leu Lys Cys Leu Thr Phe Asn Pro
                 275                 280                 285

 Ala Lys Arg Ile Ser Ala Tyr Ser Ala Leu Ser His Pro Tyr Phe
                 290                 295                 300

 Gln Asp Leu Glu Arg Cys Lys Glu Asn Leu Asp Ser His Leu Pro
                 305                 310                 315

 Pro Ser Gln Asn Thr Ser Glu Leu Asn Thr Ala
                 320                 325

<210> 6168
<211> 627
<212> DNA
<213> Homo sapien

<400> 6168
 agtctccggc gagttgttgc ctgggctgga cgtggttttg tctgctgcgc 50

 ccgctcttcg cgctctcgtt tcattttctg cagcgcgcca cgaggatggc 100

 ccacaagcag atctactact cggacaagta cttcgacgaa cactacgagt 150

 accggcatgt tatgttaccc agagaacttt ccaaacaagt acctaaaact 200

 catctgatgt ctgaagagga gtggaggaga cttggtgtcc aacagagtct 250

 aggctgggtt cattacatga ttcatgagcc agaaccacat attcttctct 300

 ttagacgacc tcttccaaaa gatcaacaaa aatgaagttt atctggggat 350

 cgtcaaatct ttttcaaatt taatgtatat gtgtatataa ggtagtattc 400

 agtgaatact tgagaaatgt acaaatcttt catccatacc tgtgcatgag 450

 ctgtattctt cacagcaaca gagctcagtt aaatgcaact gcaagtaggt 500

 tactgtaaga tgtttaagat aaaagttctt ccagtcagtt tttctcttaa 550

 gtgcctgttt gagtttactg aaacagttta cttttgttca ataaagtttg 600

 tatgttgcat ttaaaaaaaa aaaaaaa 627

<210> 6169
<211> 79
<212> PRT
<213> Homo sapien

<400> 6169
 Met Ala His Lys Gln Ile Tyr Tyr Ser Asp Lys Tyr Phe Asp Glu
   1               5                  10                  15

 His Tyr Glu Tyr Arg His Val Met Leu Pro Arg Glu Leu Ser Lys
                  20                  25                  30

 Gln Val Pro Lys Thr His Leu Met Ser Glu Glu Glu Trp Arg Arg
                  35                  40                  45

 Leu Gly Val Gln Gln Ser Leu Gly Trp Val His Tyr Met Ile His
                  50                  55                  60

 Glu Pro Glu Pro His Ile Leu Leu Phe Arg Arg Pro Leu Pro Lys
                  65                  70                  75

 Asp Gln Gln Lys


<210> 6170
<211> 4004
<212> DNA
<213> Homo sapien

<400> 6170
 agcggagtgc agggatgtgc agatgagtgg gctgtggggt gtcctgctca 50

 cggtttcatg gatgaatggc ttattcagaa gagcataaag gtatgccctg 100

 tggtttcatc cgccagaatt ccggcaactc catttccttg gactttgagc 150

 ccagtataga gtaccagttt gtggagcggt tggaagagcg ctacaaatgt 200

 gccttctgcc actcggtgct tcacaacccc caccagacag gatgtgggca 250

 ccgcttctgc cagcactgca tcctgtccct gagagaatta aacacagtgc 300

 caatctgccc tgtagataaa gaggtcatca aatctcagga ggtttttaaa 350

 gacaattgtt gcaaaagaga agtcctcaac ttatatgtat attgcagcaa 400

 tgctcctgga tgtaatgcca aggttattct gggccggtac caggatcacc 450

 ttcagcagtg cttatttcaa cctgtgcagt gttctaatga gaagtgccgg 500

 gagccagtcc tacggaaaga cctgaaagag catttgagtg catcctgtca 550

 gtttcgaaag gaaaaatgcc tttattgcaa aaaggatgtg gtagtcatca 600

 atctacagaa tcatgaggaa aacttgtgtc ctgaataccc agtattttgt 650

 cccaacaatt gtgcgaagat tattctaaaa actgaggtag atgaacacct 700

 ggctgtatgt cctgaagctg agcaagactg tccttttaag cactatggct 750

 gtgctgtaac ggataaacgg aggaacctgc agcaacatga gcattcagcc 800

 ttacgggagc acatgcgttt ggttttagaa aagaatgtcc aattagaaga 850

 acagatttct gacttacaca agagcctaga acagaaagaa agtaaaatcc 900

 agcagctagc agaaactata aagaaacttg aaaaggagtt caagcagttt 950

 gcacagttgt ttggcaaaaa tggaagcttc ctcccaaaca tccaggtttt 1000

 tgccagtcac attgacaagt cagcttggct agaagctcaa gtgcatcaat 1050

 tattacaaat ggttaaccag caacaaaata aatttgacct gagacctttg 1100

 atggaagcag ttgatacagt gaaacagaaa attaccctgc tagaaaacaa 1150

 tgatcaaaga ttagccgttt tagaagagga aactaacaaa catgataccc 1200

 acattaatat tcataaagca cagctgagta aaaatgaaga gcgatttaaa 1250

 ctgctggagg gtacttgcta taatggaaag ctcatttgga aggtgacaga 1300

 ttacaagatg aagaagagag aggcggtgga tgggcacaca gtgtccatct 1350

 tcagccagtc cttctacacc agccgctgtg gctaccggct ctgtgctaga 1400

 gcatacctga atggggatgg gtcagggagg gggtcacacc tgtccctata 1450

 ctttgtggtc atgcgaggag agtttgactc actgttgcag tggccattca 1500

 ggcagagggt gaccctgatg cttctggacc agagtggcaa aaagaacatt 1550

 atggagacct tcaaacctga ccccaatagc agcagcttta aaagacctga 1600

 tggggagatg aacattgcat ctggctgtcc ccgctttgtg gctcattctg 1650

 ttttggagaa tgccaagaac gcctacatta aagatgacac tctgttcttg 1700

 aaagtggccg tggacttaac tgacctggag gatctctagt cactgttatg 1750

 gggtgataag aggacttctt ggggccagaa ctgtggagga gagcacattt 1800

 gattatcata ttgacctgga tttagactca aagcacattt gtatttgcct 1850

 ttttccttaa cgtttgaagt cagtttaaaa cttctgaagt gctgtctttt 1900

 tacattttac tctgtcccag tttgaaactt aaaactctta gaatattctc 1950

 ttattattta tatttttata tttcttgaaa gatggtaagt ttcttgaagt 2000

 ttttggggcg tttctctttt actggtgctt agcgcagtgt ctcgggcact 2050

 ctaaatattg agtgttatgg aggacacaga ggtagcagaa tcccagttga 2100

 aaatgttttg atattttatt gtttggccta ttgattctag acctggcctt 2150

 aagtctgcaa aagccatctt tataaggtag gctgttccag ttaagaagtg 2200

 ggtgatgtag ttacaaagat aatatgctca gtttggacct ttttttcagt 2250

 taaatgctaa atatatgaaa attactatac ctctaagtat tttcatgaaa 2300

 ttcaccagca gtttgcaagc acagttttgc aaggctgcat aagaactggt 2350

 gaatggggta agcattttca ttcttcctgc tgaagtaaag cagaaagtac 2400

 tgcatagtat atgagatata gccagctagc taaagttcag attttgttag 2450

 gttcaaccct atgaaaaaaa ctattttcat aggtcaaaaa tggtaaaaaa 2500

 ttagcagttt cataagattc aaccaaataa atatatatat acacacacac 2550

 atacatatac acctatatat gtgtgtatac aaacagttcg aatgtatttt 2600

 ggtgacagta ataaatcaat gtgaggatgg atagaattta gtatatgata 2650

 gagaaaatgt cataaatgga taaaaggaat ttacaacttg aggagaaaac 2700

 ctttacaatt tcctatgggt gtcagaagta ctctcagcga aaactgatgg 2750

 ctaaaacagt atctactatt ctctgataac tttttttttg agacagagtt 2800

 tcattgtcac ccaggctgga gtacagtggc atgatctcag ctcactgcaa 2850

 actctgcctc ccgaattcaa gtgattctcc tgcctcagcc tcctgagtag 2900

 ctgggattac aggcgcccgt caccacaccc aggtaatttt tgtattttta 2950

 gtagagacgg agttttgcca tgttggccaa gctgatctca aactcctgac 3000

 ctcaagtgat ctgcccgcct cggcctccca aagtgctgag attacaggca 3050

 tgacccaccg cgtcaagcct ctgacaacta ttgaatttgt aagctgctat 3100

 gcaaatgggc atttatataa acttgtgatg tttcttgtca gaattctgag 3150

 tactctgtga agaacagaaa tgatcatatt cttatgcatc tatctgtatg 3200

 ggtctgaagg tgtatataca aactgagatg agtccttatg actcttgata 3250

 agcctgagtt taacaacaac aaaaatgcca agttgtcctg agcccttctg 3300

 cgttgttatg ccacttccct actgctcata tgcacgctgg ctcccctggg 3350

 cacgcaagga tgagtatggg ccatgggccc ctgtagagct gcttacctgg 3400

 tgatgaccat gcaccttaca atttctgaac agttaaccct atagaagcat 3450

 gctttatatg agtgtcttct gggaagagga accttcttaa tctcttctgt 3500

 gggattttca aaatgctaaa gactcacact gcagcaatca tcccagatga 3550

 ttaaattcaa agaaataggt tcacaacagg aatatactga agaactagag 3600

 tgtcactgct ggtgaactgt ggcacggttg ctcaacacat cacctcggac 3650

 aaattcagga agcatttctt tagcccacaa gtccagaccc aggtgctctg 3700

 tatgtttgtt tttaatattc atcatatcca agttcactct gtcttcctga 3750

 gcagtggaag atcatattgc tgtaacttct tttaagtagt tgatgtggaa 3800

 aacattttaa agtgaatttg tcaaaatgct ggttttgtgt tttatccaac 3850

 ttttgtgcat atatataaag tatgtcatgg catggtttgc ttaggagttc 3900

 agagttcctt catcatcgaa atagtgatta agtgatccca gaacaaggaa 3950

 tactagagta aaaagcacct ctttttcaca aaaaaaaaaa aaaaaaaaaa 4000

 aaaa 4004

<210> 6171
<211> 557
<212> PRT
<213> Homo sapien

<400> 6171
 Met Ala Tyr Ser Glu Glu His Lys Gly Met Pro Cys Gly Phe Ile
   1               5                  10                  15

 Arg Gln Asn Ser Gly Asn Ser Ile Ser Leu Asp Phe Glu Pro Ser
                  20                  25                  30

 Ile Glu Tyr Gln Phe Val Glu Arg Leu Glu Glu Arg Tyr Lys Cys
                  35                  40                  45

 Ala Phe Cys His Ser Val Leu His Asn Pro His Gln Thr Gly Cys
                  50                  55                  60

 Gly His Arg Phe Cys Gln His Cys Ile Leu Ser Leu Arg Glu Leu
                  65                  70                  75

 Asn Thr Val Pro Ile Cys Pro Val Asp Lys Glu Val Ile Lys Ser
                  80                  85                  90

 Gln Glu Val Phe Lys Asp Asn Cys Cys Lys Arg Glu Val Leu Asn
                  95                 100                 105

 Leu Tyr Val Tyr Cys Ser Asn Ala Pro Gly Cys Asn Ala Lys Val
                 110                 115                 120

 Ile Leu Gly Arg Tyr Gln Asp His Leu Gln Gln Cys Leu Phe Gln
                 125                 130                 135

 Pro Val Gln Cys Ser Asn Glu Lys Cys Arg Glu Pro Val Leu Arg
                 140                 145                 150

 Lys Asp Leu Lys Glu His Leu Ser Ala Ser Cys Gln Phe Arg Lys
                 155                 160                 165

 Glu Lys Cys Leu Tyr Cys Lys Lys Asp Val Val Val Ile Asn Leu
                 170                 175                 180

 Gln Asn His Glu Glu Asn Leu Cys Pro Glu Tyr Pro Val Phe Cys
                 185                 190                 195

 Pro Asn Asn Cys Ala Lys Ile Ile Leu Lys Thr Glu Val Asp Glu
                 200                 205                 210

 His Leu Ala Val Cys Pro Glu Ala Glu Gln Asp Cys Pro Phe Lys
                 215                 220                 225

 His Tyr Gly Cys Ala Val Thr Asp Lys Arg Arg Asn Leu Gln Gln
                 230                 235                 240

 His Glu His Ser Ala Leu Arg Glu His Met Arg Leu Val Leu Glu
                 245                 250                 255

 Lys Asn Val Gln Leu Glu Glu Gln Ile Ser Asp Leu His Lys Ser
                 260                 265                 270

 Leu Glu Gln Lys Glu Ser Lys Ile Gln Gln Leu Ala Glu Thr Ile
                 275                 280                 285

 Lys Lys Leu Glu Lys Glu Phe Lys Gln Phe Ala Gln Leu Phe Gly
                 290                 295                 300

 Lys Asn Gly Ser Phe Leu Pro Asn Ile Gln Val Phe Ala Ser His
                 305                 310                 315

 Ile Asp Lys Ser Ala Trp Leu Glu Ala Gln Val His Gln Leu Leu
                 320                 325                 330

 Gln Met Val Asn Gln Gln Gln Asn Lys Phe Asp Leu Arg Pro Leu
                 335                 340                 345

 Met Glu Ala Val Asp Thr Val Lys Gln Lys Ile Thr Leu Leu Glu
                 350                 355                 360

 Asn Asn Asp Gln Arg Leu Ala Val Leu Glu Glu Glu Thr Asn Lys
                 365                 370                 375

 His Asp Thr His Ile Asn Ile His Lys Ala Gln Leu Ser Lys Asn
                 380                 385                 390

 Glu Glu Arg Phe Lys Leu Leu Glu Gly Thr Cys Tyr Asn Gly Lys
                 395                 400                 405

 Leu Ile Trp Lys Val Thr Asp Tyr Lys Met Lys Lys Arg Glu Ala
                 410                 415                 420

 Val Asp Gly His Thr Val Ser Ile Phe Ser Gln Ser Phe Tyr Thr
                 425                 430                 435

 Ser Arg Cys Gly Tyr Arg Leu Cys Ala Arg Ala Tyr Leu Asn Gly
                 440                 445                 450

 Asp Gly Ser Gly Arg Gly Ser His Leu Ser Leu Tyr Phe Val Val
                 455                 460                 465

 Met Arg Gly Glu Phe Asp Ser Leu Leu Gln Trp Pro Phe Arg Gln
                 470                 475                 480

 Arg Val Thr Leu Met Leu Leu Asp Gln Ser Gly Lys Lys Asn Ile
                 485                 490                 495

 Met Glu Thr Phe Lys Pro Asp Pro Asn Ser Ser Ser Phe Lys Arg
                 500                 505                 510

 Pro Asp Gly Glu Met Asn Ile Ala Ser Gly Cys Pro Arg Phe Val
                 515                 520                 525

 Ala His Ser Val Leu Glu Asn Ala Lys Asn Ala Tyr Ile Lys Asp
                 530                 535                 540

 Asp Thr Leu Phe Leu Lys Val Ala Val Asp Leu Thr Asp Leu Glu
                 545                 550                 555

 Asp Leu


<210> 6172
<211> 2251
<212> DNA
<213> Homo sapien

<400> 6172
 ctgggatcag gcaaccctct cacctcagcc tcccaagtag ctgggactac 50

 aggtgcacgc taccatgcct ggctaatttt tttgtacttt tagtaaagac 100

 ggggttttgt catgttgctc gggctagcct caaactcctg ggctcaagcg 150

 atcctccctc ctcggcctcc caaagtgctg ggattacagg cttgagccac 200

 cgcacctggc cttccccatt tttctcttaa tccatatctc agacaggaat 250

 ctgtatctct cactctacag atcattctgt aggcactatg ctaaactgac 300

 accagtttca aatttagtcc ttaattgatc ttggccttta ggtgagcaaa 350

 gttacagtgg taaattacgc tccttcgctt acaaaatctc ttgcttggta 400

 tttattcccc aggggttaca tagaatagag tggaggcagt agacatggag 450

 aaatcctatc ttttaagaaa gaaaaaaatg ggcatttttc tcatggggaa 500

 ggatttttat ttttcaaata ggtgtttgaa ctgtaatgat ttcatgacat 550

 ctgcctaacg gttttgtttc tttgtcttac agaaacaaac agtcgttgct 600

 gtcaaaaaag agatcatgta ttaccaacag gccttgatga ggtccacagt 650

 gaagtcttct gtgtccctgg gagggattgt gaaatacagt gagcagttct 700

 catccaacga tgccatcatg tcaggctgcc tccccagcaa cccctggatc 750

 accgatgaca cccagttctg ggacttaaat gccaaattgg tggaaatccc 800

 aaccaagatg cgagtggaac gatgggcctt caacttcagc gaattgatcc 850

 gagaccccaa aggtcgacag agcttccagt acttcctcaa gaaagaattc 900

 agtggagaga atctgggatt ctgggaagcc tgcgaggatc tgaagtatgg 950

 agatcagtcc aaagtcaagg agaaagcaga ggagatttac aagctgttcc 1000

 tggccccggg ggcgaggcgc tggatcaaca tagatggcaa aaccatggac 1050

 atcaccgtga aggggctgaa gcacccccac cgctatgtgc tggacgccgc 1100

 acaaacccac atttacatgc tcatgaagaa ggattcttat gctcgctatt 1150

 taaaatctcc gatctataag gacatgcagg ccaaagctat tgaccctcag 1200

 gaaacaacca agaaaagctc caccctccct tttatgcggc gtcacctgcg 1250

 ctccagccca agccctgtca tcctgagaca gctggaagag gaagccaagg 1300

 cccgagaagc agccaacact gtggacatca cccagccggg ccagcacatg 1350

 gctcccagcc cccatctgac cgtgtacacc gggacctgca tgcccccgtc 1400

 tccttctagc cccttctcct cctcctgccg ctcccccagg aagcctttcg 1450

 cctcacccag ccgcttcatc cggcgaccaa ccatctgccc ctcaccgatc 1500

 ctagtggtct tggatagctc atcgggcttg gagcagaaag gggagtgcag 1550

 ctggtctggt gccaaccctg ggccctctgt caccgacagc agcgaggcct 1600

 cccgcgacac ctcctggact cgcagccggc ccagggcccc tctcaaggcc 1650

 cgcatggctc tgtccttcag caggtttctg agacgaggct gtctggcttc 1700

 acctgtcttt gccagggtgt cacccaagtg ccctgctgtg tcccacggga 1750

 gggtgcagcc cctgggggac gtgggccagc agctgccacg attgaaatcc 1800

 aagagagtag caaacttttt ccagatcaaa atggatgtgc ccacggggag 1850

 cgggacctgc ttgatggact cggaggatgc tggaacagga gagtcgggtg 1900

 accgggccac agaaaaggag gtcatctgcc cctgggagag cctgtaagga 1950

 aagaggcagg ctgagttggg ggctctggac caggaagatg ttctgacaga 2000

 tgccatggta tgggccacag gacacacttg ctcgagaacc aaagtgcatt 2050

 tgggtgacat ttgaagattg gggagacaag atggggtaga ttgtggcaaa 2100

 gaatgctctg gctggttacc aggggccaac tccttctcct cttcctgacc 2150

 ctccctcccc tgggcagaag aaacgcatgt ggaccagaag actttccctg 2200

 ctgccttaaa accaataaaa ggttaaattg aaaaaaaaaa aaaaaaaaaa 2250

 a 2251

<210> 6173
<211> 443
<212> PRT
<213> Homo sapien

<400> 6173
 Met Tyr Tyr Gln Gln Ala Leu Met Arg Ser Thr Val Lys Ser Ser
   1               5                  10                  15

 Val Ser Leu Gly Gly Ile Val Lys Tyr Ser Glu Gln Phe Ser Ser
                  20                  25                  30

 Asn Asp Ala Ile Met Ser Gly Cys Leu Pro Ser Asn Pro Trp Ile
                  35                  40                  45

 Thr Asp Asp Thr Gln Phe Trp Asp Leu Asn Ala Lys Leu Val Glu
                  50                  55                  60

 Ile Pro Thr Lys Met Arg Val Glu Arg Trp Ala Phe Asn Phe Ser
                  65                  70                  75

 Glu Leu Ile Arg Asp Pro Lys Gly Arg Gln Ser Phe Gln Tyr Phe
                  80                  85                  90

 Leu Lys Lys Glu Phe Ser Gly Glu Asn Leu Gly Phe Trp Glu Ala
                  95                 100                 105

 Cys Glu Asp Leu Lys Tyr Gly Asp Gln Ser Lys Val Lys Glu Lys
                 110                 115                 120

 Ala Glu Glu Ile Tyr Lys Leu Phe Leu Ala Pro Gly Ala Arg Arg
                 125                 130                 135

 Trp Ile Asn Ile Asp Gly Lys Thr Met Asp Ile Thr Val Lys Gly
                 140                 145                 150

 Leu Lys His Pro His Arg Tyr Val Leu Asp Ala Ala Gln Thr His
                 155                 160                 165

 Ile Tyr Met Leu Met Lys Lys Asp Ser Tyr Ala Arg Tyr Leu Lys
                 170                 175                 180

 Ser Pro Ile Tyr Lys Asp Met Gln Ala Lys Ala Ile Asp Pro Gln
                 185                 190                 195

 Glu Thr Thr Lys Lys Ser Ser Thr Leu Pro Phe Met Arg Arg His
                 200                 205                 210

 Leu Arg Ser Ser Pro Ser Pro Val Ile Leu Arg Gln Leu Glu Glu
                 215                 220                 225

 Glu Ala Lys Ala Arg Glu Ala Ala Asn Thr Val Asp Ile Thr Gln
                 230                 235                 240

 Pro Gly Gln His Met Ala Pro Ser Pro His Leu Thr Val Tyr Thr
                 245                 250                 255

 Gly Thr Cys Met Pro Pro Ser Pro Ser Ser Pro Phe Ser Ser Ser
                 260                 265                 270

 Cys Arg Ser Pro Arg Lys Pro Phe Ala Ser Pro Ser Arg Phe Ile
                 275                 280                 285

 Arg Arg Pro Thr Ile Cys Pro Ser Pro Ile Leu Val Val Leu Asp
                 290                 295                 300

 Ser Ser Ser Gly Leu Glu Gln Lys Gly Glu Cys Ser Trp Ser Gly
                 305                 310                 315

 Ala Asn Pro Gly Pro Ser Val Thr Asp Ser Ser Glu Ala Ser Arg
                 320                 325                 330

 Asp Thr Ser Trp Thr Arg Ser Arg Pro Arg Ala Pro Leu Lys Ala
                 335                 340                 345

 Arg Met Ala Leu Ser Phe Ser Arg Phe Leu Arg Arg Gly Cys Leu
                 350                 355                 360

 Ala Ser Pro Val Phe Ala Arg Val Ser Pro Lys Cys Pro Ala Val
                 365                 370                 375

 Ser His Gly Arg Val Gln Pro Leu Gly Asp Val Gly Gln Gln Leu
                 380                 385                 390

 Pro Arg Leu Lys Ser Lys Arg Val Ala Asn Phe Phe Gln Ile Lys
                 395                 400                 405

 Met Asp Val Pro Thr Gly Ser Gly Thr Cys Leu Met Asp Ser Glu
                 410                 415                 420

 Asp Ala Gly Thr Gly Glu Ser Gly Asp Arg Ala Thr Glu Lys Glu
                 425                 430                 435

 Val Ile Cys Pro Trp Glu Ser Leu
                 440

<210> 6174
<211> 664
<212> DNA
<213> Homo sapien

<400> 6174
 ggattgttgg tctgcgtgga acttctcagg tggacaccag agcatggaac 50

 acatccacga cagcgatggc agttccagca gcagccacca gagcctcaag 100

 agcacagcca aatgggcggc atccctggag aatctgctgg aagacccaga 150

 aggcgtgaaa agatttaggg aatttttaaa aaaggaattc agtgaagaaa 200

 atgttttgtt ttggctagca tgtgaagatt ttaagaaaat gcaagataag 250

 acgcagatgc aggaaaaggc aaaggagatc tacatgacct ttctgtccag 300

 caaggcctca tcacaggtca acgtggaggg gcagtctcgg ctcaacgaga 350

 agatcctgga agaaccgcac cctctgatgt tccagaaact ccaggaccag 400

 atctttaatc tcatgaagta cgacagctac agccgctttc ttaagtctga 450

 cttgttttta aaacacaagc gaaccgagga agaggaagaa gatttgcctg 500

 atgctcaaac tgcagctaaa agagcttcca gaatttataa cacatgagcc 550

 cccaaaaagc cgggactggc agctttaaga agcaaaggaa tttcctctca 600

 ggacgtgccg ggtttatcat tgctttgtta tttgtaagga ctgaaatgta 650

 caaaaccctt caat 664

<210> 6175
<211> 167
<212> PRT
<213> Homo sapien

<400> 6175
 Met Glu His Ile His Asp Ser Asp Gly Ser Ser Ser Ser Ser His
   1               5                  10                  15

 Gln Ser Leu Lys Ser Thr Ala Lys Trp Ala Ala Ser Leu Glu Asn
                  20                  25                  30

 Leu Leu Glu Asp Pro Glu Gly Val Lys Arg Phe Arg Glu Phe Leu
                  35                  40                  45

 Lys Lys Glu Phe Ser Glu Glu Asn Val Leu Phe Trp Leu Ala Cys
                  50                  55                  60

 Glu Asp Phe Lys Lys Met Gln Asp Lys Thr Gln Met Gln Glu Lys
                  65                  70                  75

 Ala Lys Glu Ile Tyr Met Thr Phe Leu Ser Ser Lys Ala Ser Ser
                  80                  85                  90

 Gln Val Asn Val Glu Gly Gln Ser Arg Leu Asn Glu Lys Ile Leu
                  95                 100                 105

 Glu Glu Pro His Pro Leu Met Phe Gln Lys Leu Gln Asp Gln Ile
                 110                 115                 120

 Phe Asn Leu Met Lys Tyr Asp Ser Tyr Ser Arg Phe Leu Lys Ser
                 125                 130                 135

 Asp Leu Phe Leu Lys His Lys Arg Thr Glu Glu Glu Glu Glu Asp
                 140                 145                 150

 Leu Pro Asp Ala Gln Thr Ala Ala Lys Arg Ala Ser Arg Ile Tyr
                 155                 160                 165

 Asn Thr


<210> 6176
<211> 417
<212> DNA
<213> Homo sapien

<400> 6176
 atggcaaagc aaccttctga tgtaagttct gagtgtgacc gagaaggtag 50

 acaattgcag cctgcggaga ggcctcccca gctcagacct ggggccccta 100

 cctccctaca gacagagcca caagacagga gcccagcacc catgagttgt 150

 gacaaatcaa cacaaacccc aagtcctcct tgccaggcct tcaaccacta 200

 tctcagtgca atggcttcca tgaggcaggc tgaacctgca gatatgcgcc 250

 cagagatatg gatcgcccaa gagttgcggc gtatcggaga cgagtttaac 300

 gcttactatg caaggagggt atttttgaat aattaccaag cagccgaaga 350

 ccacccacga atggttatct tacgactgtt acgttacatt gtccgcctgg 400

 tgtggagaat gcattga 417

<210> 6177
<211> 138
<212> PRT
<213> Homo sapien

<400> 6177
 Met Ala Lys Gln Pro Ser Asp Val Ser Ser Glu Cys Asp Arg Glu
   1               5                  10                  15

 Gly Arg Gln Leu Gln Pro Ala Glu Arg Pro Pro Gln Leu Arg Pro
                  20                  25                  30

 Gly Ala Pro Thr Ser Leu Gln Thr Glu Pro Gln Asp Arg Ser Pro
                  35                  40                  45

 Ala Pro Met Ser Cys Asp Lys Ser Thr Gln Thr Pro Ser Pro Pro
                  50                  55                  60

 Cys Gln Ala Phe Asn His Tyr Leu Ser Ala Met Ala Ser Met Arg
                  65                  70                  75

 Gln Ala Glu Pro Ala Asp Met Arg Pro Glu Ile Trp Ile Ala Gln
                  80                  85                  90

 Glu Leu Arg Arg Ile Gly Asp Glu Phe Asn Ala Tyr Tyr Ala Arg
                  95                 100                 105

 Arg Val Phe Leu Asn Asn Tyr Gln Ala Ala Glu Asp His Pro Arg
                 110                 115                 120

 Met Val Ile Leu Arg Leu Leu Arg Tyr Ile Val Arg Leu Val Trp
                 125                 130                 135

 Arg Met His


<210> 6178
<211> 670
<212> DNA
<213> Homo sapien

<400> 6178
 ggcacgagct catctgacga ctgacagctg atggcaccgc cagcctctgt 50

 cccttggcca ggactgtcac acggctgact ctcagcaggg gcagtagaat 100

 gaaagagggc atgtctaata acagcaccac tagcatctcc caagccagga 150

 aagctgtgga gcagctaaag atggaagcct gtatggacag ggtcaaggtc 200

 tcccaggcag ccgcggacct cctggcctac tgtgaagctc acgtgcggga 250

 agatcctctc atcattccag tgcctgcatc agaaaacccc tttcgcgaga 300

 agaagttctt ttgtaccatt ctctaactcc gtgtgtgatg aaaacgcctc 350

 cttttctgac cttcaaagtc ccctgtagag accatgcatg ctctaagcct 400

 tagggagtga gaccaacacc catccctgcc cagccaacag tggccggggc 450

 ttgtcttatg tttccatctg ttttcttcgt ggcattcaat ttcatttttt 500

 tccttttcat tttcatgtta ttttcattat tggcaaagaa aatcaaaatg 550

 tttatagcca aataacaaat gtgccatgta aaagtaagtc tggacttaag 600

 agtttaaaat ttttaaacat cagtttccaa gtttatatca tattaataca 650

 tttcagtgga taatttattt 670

<210> 6179
<211> 75
<212> PRT
<213> Homo sapien

<400> 6179
 Met Lys Glu Gly Met Ser Asn Asn Ser Thr Thr Ser Ile Ser Gln
   1               5                  10                  15

 Ala Arg Lys Ala Val Glu Gln Leu Lys Met Glu Ala Cys Met Asp
                  20                  25                  30

 Arg Val Lys Val Ser Gln Ala Ala Ala Asp Leu Leu Ala Tyr Cys
                  35                  40                  45

 Glu Ala His Val Arg Glu Asp Pro Leu Ile Ile Pro Val Pro Ala
                  50                  55                  60

 Ser Glu Asn Pro Phe Arg Glu Lys Lys Phe Phe Cys Thr Ile Leu
                  65                  70                  75

<210> 6180
<211> 3164
<212> DNA
<213> Homo sapien

<400> 6180
 cggcctcaga aagccgagtg aggagttggc cgtagtgaga gggaccgatc 50

 ccttggggcc gccggcggcg aggccgagcc gctcctccca atggcgaaga 100

 agacgtacga cctgcttttc aagctgctcc tgatcgggga ttccggagtg 150

 gggaagacct gcgtcctttt tcgtttttcg gatgatgcct tcaatactac 200

 ctttatttcc accataggaa tagacttcaa gatcaaaaca gttgaattac 250

 aaggaaagaa gatcaagcta cagatatggg atacagcagg ccaggagcga 300

 tttcacacca tcacaacctc ctactacaga ggcgcaatgg gtatcatgct 350

 agtatatgac atcaccaatg gtaaaagttt tgaaaacatc agcaaatggc 400

 ttagaaacat agatgagcat gccaatgaag atgtggaaag aatgttacta 450

 ggaaacaagt gtgatatgga cgacaaaaga gttgtaccta aaggaaaagg 500

 agaacagatt gcaagggagc atggtattag gttttttgag actagtgcaa 550

 aagcaaatat aaacatcgaa aaggcgttcc tcacgttagc tgaagatatc 600

 cttcgaaaga cccctgtaaa agagcccaac agtgaaaatg tagatatcag 650

 cagtggagga ggcgtgacag gctggaagag caaatgctgc tgagcattct 700

 cctgttccat cagttgccat ccactacccc gttttctctt cttgctgcaa 750

 aataaaccac tctgtccatt tttaactcta aacagatatt tttgtttctc 800

 atcttaacta tccaagccac ctattttatt tgttctttca tctgtgactg 850

 cttgctgact ttatcataat tttcttcaaa caaaaaaatg tatagaaaaa 900

 tcatgtctgt gacttcattt ttaaatgtac ttgctcagct caactgcatt 950

 tcagttgtat tatagtccag ttcttatcaa cattaaaacc tatagcaatc 1000

 atttcaaatc tattctgcaa attgtataag aataaagtta gaattaacaa 1050

 ttttattttg tacaacagtg gaattttctg tcatggataa tgtgcttgag 1100

 tccctataat ctatagacat gtgatagcaa aagaaacaaa caaaagccag 1150

 gaaaacactc attttcgcct tgaatatgta aatgggatta attttgtcct 1200

 gtgccttatg tggaaaggga cttctttggg ttttcctttt ttgttctggt 1250

 ggaagcatgt gcagggagac catatcatcc aaaccataaa cccattaaaa 1300

 tgtttgtggt ttgcttggct gtaattttca aagtagttaa ttgaggacaa 1350

 agggtaatgc agaagtgata gctttggttt gctgagtctt gttttaagtg 1400

 gccttgatat ttaaaactat tcctgccacc atttcttctc cttggccact 1450

 tcttccttgc gtctccctgc atgctgcttt atttgcttct ccctccccaa 1500

 ccacctcatg gtatatttaa gagtgaaagg gacaaactag taggtttgtc 1550

 aagtttaata taaagcactg atgtaacttg ctaggtaaac ggaaagataa 1600

 gttctaactg cctactatcc aatgtcagtt aattggtgtc ttcccccctc 1650

 atttgctctc ttccctaaaa tgtgtcccag atgccttcat ttgctgtttt 1700

 acttctatgt tctgcttttc ctcctctctt tgttcccttc ctgtctatcc 1750

 attgagttta tgaaatggaa gagttaactg catgcactag tgtttggagg 1800

 gtgttgtggt ttgtctttct aattaggtgt atagcctatt cactttccta 1850

 ggaataaatc tcttaaccta aatttgagta gtctgcattt tggcaactcc 1900

 tctaagcagc ttggtagcct aagtacaggt tgttttttta aaaaaggaaa 1950

 agcaggaagg aggagtgaat tttattaaca tgtttgccaa atgtattgag 2000

 atttggcctc tgaagaacac tttttcagtg ttaagtttct ttaccttaag 2050

 attccgaaat actttagaat attattaatt ttaagtcctg tctttacatc 2100

 cttttggaaa acttgtatta ccatgagttt ggaaaaagga caacgaaagg 2150

 cttttcatgt aaagataaga tctttagcta tctctaaccc tgtccttttt 2200

 tcactgcatt ttttctagtt ttgcttcatt gcttatcatt aggatagggt 2250

 aagtgaagtt tgctatgctg ctagcatcct aagatgatac ctttgttgaa 2300

 agaattgtga atagcatgat tcatttctag cagaggctga gtttaggaca 2350

 gcagcttcca ttgagaagtc tttctgtgtc gtgaatagca ttttaatgac 2400

 ctcttggctc acataagcaa acaacatagg gacgtatctg ctatgaaaat 2450

 ccacaaattt ttcagatagt gccctaaaaa caattttata tgcctcactg 2500

 gttgttattc ttaggttatt cccacacttg actttatcat tgtttactac 2550

 tagtaaaaag cagcattgcc aaataatccc taattttcca ctaaaaatat 2600

 aatgaaatga tgttaagctt tttgaaaagt ttaggttaaa cctactgttg 2650

 ttagattaat gtatttgttg cttcccttta tctggaatgt ggcattagct 2700

 tttttatttt aaccctcttt aattcttatt caattccatg acttaaggtt 2750

 ggagagctaa acactgggat ttttggataa cagactgaca gttttgcata 2800

 attataatcg gcattgtaca tagaaaggat atggctacct tttgttaaat 2850

 ctgcactttc taaatatcaa aaaagggaaa tgaagtataa atcaattttt 2900

 gtataatctg tttgaaacat gagttttatt tgcttaatat tagctttgcc 2950

 ccttttctgt aagtctcttg ggatcctgtg tagaagctgt tctcattaaa 3000

 caccaaacag ttaagtccat tctctggtac tagctacaaa ttcggtttca 3050

 tattctactt aacaatttaa ataaactgaa atatttctag atggtctact 3100

 tctgttcata taaaaacaaa acttgatttc caaaaaaaaa aaaaaaaaaa 3150

 aaaaaaaaaa aaaa 3164

<210> 6181
<211> 200
<212> PRT
<213> Homo sapien

<400> 6181
 Met Ala Lys Lys Thr Tyr Asp Leu Leu Phe Lys Leu Leu Leu Ile
   1               5                  10                  15

 Gly Asp Ser Gly Val Gly Lys Thr Cys Val Leu Phe Arg Phe Ser
                  20                  25                  30

 Asp Asp Ala Phe Asn Thr Thr Phe Ile Ser Thr Ile Gly Ile Asp
                  35                  40                  45

 Phe Lys Ile Lys Thr Val Glu Leu Gln Gly Lys Lys Ile Lys Leu
                  50                  55                  60

 Gln Ile Trp Asp Thr Ala Gly Gln Glu Arg Phe His Thr Ile Thr
                  65                  70                  75

 Thr Ser Tyr Tyr Arg Gly Ala Met Gly Ile Met Leu Val Tyr Asp
                  80                  85                  90

 Ile Thr Asn Gly Lys Ser Phe Glu Asn Ile Ser Lys Trp Leu Arg
                  95                 100                 105

 Asn Ile Asp Glu His Ala Asn Glu Asp Val Glu Arg Met Leu Leu
                 110                 115                 120

 Gly Asn Lys Cys Asp Met Asp Asp Lys Arg Val Val Pro Lys Gly
                 125                 130                 135

 Lys Gly Glu Gln Ile Ala Arg Glu His Gly Ile Arg Phe Phe Glu
                 140                 145                 150

 Thr Ser Ala Lys Ala Asn Ile Asn Ile Glu Lys Ala Phe Leu Thr
                 155                 160                 165

 Leu Ala Glu Asp Ile Leu Arg Lys Thr Pro Val Lys Glu Pro Asn
                 170                 175                 180

 Ser Glu Asn Val Asp Ile Ser Ser Gly Gly Gly Val Thr Gly Trp
                 185                 190                 195

 Lys Ser Lys Cys Cys
                 200

<210> 6182
<211> 3434
<212> DNA
<213> Homo sapien

<400> 6182
 gccccgctgc ccacctgccc gcctgcccac ctgcccaggt gcgagtgcag 50

 ccccgcgcgc cggcctgaga gccctgtgga caacctcgtc attgtcaggc 100

 acagagcggt agaccctgct tctctaagtg ggcagcggac agcggcacgc 150

 acatttcacc tgtcccgcag acaacagcac catctgcttg ggagaaccct 200

 ctcccttctc tgagaaagaa agatgtcgaa tgggtattcc acagacgaga 250

 atttccgcta tctcatctcg tgcttcaggg ccagggtgaa aatgtacatc 300

 caggtggagc ctgtgctgga ctacctgacc tttctgcctg cagaggtgaa 350

 ggagcagatt cagaggacag tcgccacctc cgggaacatg caggcagttg 400

 aactgctgct gagcaccttg gagaagggag tctggcacct tggttggact 450

 cgggaattcg tggaggccct ccggagaacc ggcagccctc tggccgcccg 500

 ctacatgaac cctgagctca cggacttgcc ctctccatcg tttgagaacg 550

 ctcatgatga atatctccaa ctgctgaacc tccttcagcc cactctggtg 600

 gacaagcttc tagttagaga cgtcttggat aagtgcatgg aggaggaact 650

 gttgacaatt gaagacagaa accggattgc tgctgcagaa aacaatggaa 700

 atgaatcagg tgtaagagag ctactaaaaa ggattgtgca gaaagaaaac 750

 tggttctctg catttctgaa tgttcttcgt caaacaggaa acaatgaact 800

 tgtccaagag ttaacaggct ctgattgctc agaaagcaat gcagagattg 850

 agaatttatc acaagttgat ggtcctcaag tggaagagca acttctttca 900

 accacagttc agccaaatct ggagaaggag gtctggggca tggagaataa 950

 ctcatcagaa tcatcttttg cagattcttc tgtagtttca gaatcagaca 1000

 caagtttggc agaaggaagt gtcagctgct tagatgaaag tcttggacat 1050

 aacagcaaca tgggcagtga ttcaggcacc atgggaagtg attcagatga 1100

 agagaatgtg gcagcaagag catccccgga gccagaactc cagctcaggc 1150

 cttaccaaat ggaagttgcc cagccagcct tggaagggaa gaatatcatc 1200

 atctgcctcc ctacagggag tggaaaaacc agagtggctg tttacattgc 1250

 caaggatcac ttagacaaga agaaaaaagc atctgagcct ggaaaagtta 1300

 tagttcttgt caataaggta ctgctagttg aacagctctt ccgcaaggag 1350

 ttccaaccat ttttgaagaa atggtatcgt gttattggat taagtggtga 1400

 tacccaactg aaaatatcat ttccagaagt tgtcaagtcc tgtgatatta 1450

 ttatcagtac agctcaaatc cttgaaaact ccctcttaaa cttggaaaat 1500

 ggagaagatg ctggtgttca attgtcagac ttttccctca ttatcattga 1550

 tgaatgtcat cacaccaaca aagaagcagt gtataataac atcatgaggc 1600

 attatttgat gcagaagttg aaaaacaata gactcaagaa agaaaacaaa 1650

 ccagtgattc cccttcctca gatactggga ctaacagctt cacctggtgt 1700

 tggaggggcc acgaagcaag ccaaagctga agaacacatt ttaaaactat 1750

 gtgccaatct tgatgcattt actattaaaa ctgttaaaga aaaccttgat 1800

 caactgaaaa accaaataca ggagccatgc aagaagtttg ccattgcaga 1850

 tgcaaccaga gaagatccat ttaaagagaa acttctagaa ataatgacaa 1900

 ggattcaaac ttattgtcaa atgagtccaa tgtcagattt tggaactcaa 1950

 ccctatgaac aatgggccat tcaaatggaa aaaaaagctg caaaagaagg 2000

 aaatcgcaaa gaacgtgttt gtgcagaaca tttgaggaag tacaatgagg 2050

 ccctacaaat taatgacaca attcgaatga tagatgcgta tactcatctt 2100

 gaaactttct ataatgaaga gaaagataag aagtttgcag tcatagaaga 2150

 tgatagtgat gagggtggtg atgatgagta ttgtgatggt gatgaagatg 2200

 aggatgattt aaagaaacct ttgaaactgg atgaaacaga tagatttctc 2250

 atgactttat tttttgaaaa caataaaatg ttgaaaaggc tggctgaaaa 2300

 cccagaatat gaaaatgaaa agctgaccaa attaagaaat accataatgg 2350

 agcaatatac taggactgag gaatcagcac gaggaataat ctttacaaaa 2400

 acacgacaga gtgcatatgc gctttcccag tggattactg aaaatgaaaa 2450

 atttgctgaa gtaggagtca aagcccacca tctgattgga gctggacaca 2500

 gcagtgagtt caaacccatg acacagaatg aacaaaaaga agtcattagt 2550

 aaatttcgca ctggaaaaat aaatctgctt atcgctacca cagtggcaga 2600

 agaaggtctg gatattaaag aatgtaacat tgttatccgt tatggtctcg 2650

 tcaccaatga aatagccatg gtccaggccc gtggtcgagc cagagctgat 2700

 gagagcacct acgtcctggt tgctcacagt ggttcaggag ttatcgaaca 2750

 tgagacagtt aatgatttcc gagagaagat gatgtataaa gctatacatt 2800

 gtgttcaaaa tatgaaacca gaggagtatg ctcataagat tttggaatta 2850

 cagatgcaaa gtataatgga aaagaaaatg aaaaccaaga gaaatattgc 2900

 caagcattac aagaataacc catcactaat aactttcctt tgcaaaaact 2950

 gcagtgtgct agcctgttct ggggaagata tccatgtaat tgagaaaatg 3000

 catcacgtca atatgacccc agaattcaag gaactttaca ttgtaagaga 3050

 aaacaaagca ctgcaaaaga agtgtgccga ctatcaaata aatggtgaaa 3100

 tcatctgcaa atgtggccag gcttggggaa caatgatggt gcacaaaggc 3150

 ttagatttgc cttgtctcaa aataaggaat tttgtagtgg ttttcaaaaa 3200

 taattcaaca aagaaacaat acaaaaagtg ggtagaatta cctatcacat 3250

 ttcccaatct tgactattca gaatgctgtt tatttagtga tgaggattag 3300

 cacttgattg aagattcttt taaaatacta tcagttaaac atttaatatg 3350

 attatgatta atgtattcat tatgctacag aactgacata agaatcaata 3400

 aaatgattgt tttactctgc aaaaaaaaaa aaaa 3434

<210> 6183
<211> 1025
<212> PRT
<213> Homo sapien

<400> 6183
 Met Ser Asn Gly Tyr Ser Thr Asp Glu Asn Phe Arg Tyr Leu Ile
   1               5                  10                  15

 Ser Cys Phe Arg Ala Arg Val Lys Met Tyr Ile Gln Val Glu Pro
                  20                  25                  30

 Val Leu Asp Tyr Leu Thr Phe Leu Pro Ala Glu Val Lys Glu Gln
                  35                  40                  45

 Ile Gln Arg Thr Val Ala Thr Ser Gly Asn Met Gln Ala Val Glu
                  50                  55                  60

 Leu Leu Leu Ser Thr Leu Glu Lys Gly Val Trp His Leu Gly Trp
                  65                  70                  75

 Thr Arg Glu Phe Val Glu Ala Leu Arg Arg Thr Gly Ser Pro Leu
                  80                  85                  90

 Ala Ala Arg Tyr Met Asn Pro Glu Leu Thr Asp Leu Pro Ser Pro
                  95                 100                 105

 Ser Phe Glu Asn Ala His Asp Glu Tyr Leu Gln Leu Leu Asn Leu
                 110                 115                 120

 Leu Gln Pro Thr Leu Val Asp Lys Leu Leu Val Arg Asp Val Leu
                 125                 130                 135

 Asp Lys Cys Met Glu Glu Glu Leu Leu Thr Ile Glu Asp Arg Asn
                 140                 145                 150

 Arg Ile Ala Ala Ala Glu Asn Asn Gly Asn Glu Ser Gly Val Arg
                 155                 160                 165

 Glu Leu Leu Lys Arg Ile Val Gln Lys Glu Asn Trp Phe Ser Ala
                 170                 175                 180

 Phe Leu Asn Val Leu Arg Gln Thr Gly Asn Asn Glu Leu Val Gln
                 185                 190                 195

 Glu Leu Thr Gly Ser Asp Cys Ser Glu Ser Asn Ala Glu Ile Glu
                 200                 205                 210

 Asn Leu Ser Gln Val Asp Gly Pro Gln Val Glu Glu Gln Leu Leu
                 215                 220                 225

 Ser Thr Thr Val Gln Pro Asn Leu Glu Lys Glu Val Trp Gly Met
                 230                 235                 240

 Glu Asn Asn Ser Ser Glu Ser Ser Phe Ala Asp Ser Ser Val Val
                 245                 250                 255

 Ser Glu Ser Asp Thr Ser Leu Ala Glu Gly Ser Val Ser Cys Leu
                 260                 265                 270

 Asp Glu Ser Leu Gly His Asn Ser Asn Met Gly Ser Asp Ser Gly
                 275                 280                 285

 Thr Met Gly Ser Asp Ser Asp Glu Glu Asn Val Ala Ala Arg Ala
                 290                 295                 300

 Ser Pro Glu Pro Glu Leu Gln Leu Arg Pro Tyr Gln Met Glu Val
                 305                 310                 315

 Ala Gln Pro Ala Leu Glu Gly Lys Asn Ile Ile Ile Cys Leu Pro
                 320                 325                 330

 Thr Gly Ser Gly Lys Thr Arg Val Ala Val Tyr Ile Ala Lys Asp
                 335                 340                 345

 His Leu Asp Lys Lys Lys Lys Ala Ser Glu Pro Gly Lys Val Ile
                 350                 355                 360

 Val Leu Val Asn Lys Val Leu Leu Val Glu Gln Leu Phe Arg Lys
                 365                 370                 375

 Glu Phe Gln Pro Phe Leu Lys Lys Trp Tyr Arg Val Ile Gly Leu
                 380                 385                 390

 Ser Gly Asp Thr Gln Leu Lys Ile Ser Phe Pro Glu Val Val Lys
                 395                 400                 405

 Ser Cys Asp Ile Ile Ile Ser Thr Ala Gln Ile Leu Glu Asn Ser
                 410                 415                 420

 Leu Leu Asn Leu Glu Asn Gly Glu Asp Ala Gly Val Gln Leu Ser
                 425                 430                 435

 Asp Phe Ser Leu Ile Ile Ile Asp Glu Cys His His Thr Asn Lys
                 440                 445                 450

 Glu Ala Val Tyr Asn Asn Ile Met Arg His Tyr Leu Met Gln Lys
                 455                 460                 465

 Leu Lys Asn Asn Arg Leu Lys Lys Glu Asn Lys Pro Val Ile Pro
                 470                 475                 480

 Leu Pro Gln Ile Leu Gly Leu Thr Ala Ser Pro Gly Val Gly Gly
                 485                 490                 495

 Ala Thr Lys Gln Ala Lys Ala Glu Glu His Ile Leu Lys Leu Cys
                 500                 505                 510

 Ala Asn Leu Asp Ala Phe Thr Ile Lys Thr Val Lys Glu Asn Leu
                 515                 520                 525

 Asp Gln Leu Lys Asn Gln Ile Gln Glu Pro Cys Lys Lys Phe Ala
                 530                 535                 540

 Ile Ala Asp Ala Thr Arg Glu Asp Pro Phe Lys Glu Lys Leu Leu
                 545                 550                 555

 Glu Ile Met Thr Arg Ile Gln Thr Tyr Cys Gln Met Ser Pro Met
                 560                 565                 570

 Ser Asp Phe Gly Thr Gln Pro Tyr Glu Gln Trp Ala Ile Gln Met
                 575                 580                 585

 Glu Lys Lys Ala Ala Lys Glu Gly Asn Arg Lys Glu Arg Val Cys
                 590                 595                 600

 Ala Glu His Leu Arg Lys Tyr Asn Glu Ala Leu Gln Ile Asn Asp
                 605                 610                 615

 Thr Ile Arg Met Ile Asp Ala Tyr Thr His Leu Glu Thr Phe Tyr
                 620                 625                 630

 Asn Glu Glu Lys Asp Lys Lys Phe Ala Val Ile Glu Asp Asp Ser
                 635                 640                 645

 Asp Glu Gly Gly Asp Asp Glu Tyr Cys Asp Gly Asp Glu Asp Glu
                 650                 655                 660

 Asp Asp Leu Lys Lys Pro Leu Lys Leu Asp Glu Thr Asp Arg Phe
                 665                 670                 675

 Leu Met Thr Leu Phe Phe Glu Asn Asn Lys Met Leu Lys Arg Leu
                 680                 685                 690

 Ala Glu Asn Pro Glu Tyr Glu Asn Glu Lys Leu Thr Lys Leu Arg
                 695                 700                 705

 Asn Thr Ile Met Glu Gln Tyr Thr Arg Thr Glu Glu Ser Ala Arg
                 710                 715                 720

 Gly Ile Ile Phe Thr Lys Thr Arg Gln Ser Ala Tyr Ala Leu Ser
                 725                 730                 735

 Gln Trp Ile Thr Glu Asn Glu Lys Phe Ala Glu Val Gly Val Lys
                 740                 745                 750

 Ala His His Leu Ile Gly Ala Gly His Ser Ser Glu Phe Lys Pro
                 755                 760                 765

 Met Thr Gln Asn Glu Gln Lys Glu Val Ile Ser Lys Phe Arg Thr
                 770                 775                 780

 Gly Lys Ile Asn Leu Leu Ile Ala Thr Thr Val Ala Glu Glu Gly
                 785                 790                 795

 Leu Asp Ile Lys Glu Cys Asn Ile Val Ile Arg Tyr Gly Leu Val
                 800                 805                 810

 Thr Asn Glu Ile Ala Met Val Gln Ala Arg Gly Arg Ala Arg Ala
                 815                 820                 825

 Asp Glu Ser Thr Tyr Val Leu Val Ala His Ser Gly Ser Gly Val
                 830                 835                 840

 Ile Glu His Glu Thr Val Asn Asp Phe Arg Glu Lys Met Met Tyr
                 845                 850                 855

 Lys Ala Ile His Cys Val Gln Asn Met Lys Pro Glu Glu Tyr Ala
                 860                 865                 870

 His Lys Ile Leu Glu Leu Gln Met Gln Ser Ile Met Glu Lys Lys
                 875                 880                 885

 Met Lys Thr Lys Arg Asn Ile Ala Lys His Tyr Lys Asn Asn Pro
                 890                 895                 900

 Ser Leu Ile Thr Phe Leu Cys Lys Asn Cys Ser Val Leu Ala Cys
                 905                 910                 915

 Ser Gly Glu Asp Ile His Val Ile Glu Lys Met His His Val Asn
                 920                 925                 930

 Met Thr Pro Glu Phe Lys Glu Leu Tyr Ile Val Arg Glu Asn Lys
                 935                 940                 945

 Ala Leu Gln Lys Lys Cys Ala Asp Tyr Gln Ile Asn Gly Glu Ile
                 950                 955                 960

 Ile Cys Lys Cys Gly Gln Ala Trp Gly Thr Met Met Val His Lys
                 965                 970                 975

 Gly Leu Asp Leu Pro Cys Leu Lys Ile Arg Asn Phe Val Val Val
                 980                 985                 990

 Phe Lys Asn Asn Ser Thr Lys Lys Gln Tyr Lys Lys Trp Val Glu
                 995                1000                1005

 Leu Pro Ile Thr Phe Pro Asn Leu Asp Tyr Ser Glu Cys Cys Leu
                1010                1015                1020

 Phe Ser Asp Glu Asp
                1025

<210> 6184
<211> 4193
<212> DNA
<213> Homo sapien

<400> 6184
 catggcggcg actgcggcaa agcgagagcc tcggagacgc cgctgccgcc 50

 agcacagccg gagatctgag ccgacactgg gggcagtccg cgagccccgc 100

 actctctcga tgagtcggag aagtcccgtt gtatcagagt aagatggacg 150

 gtagctttga ttgtgattgt ggtgagctgg agccacctga tcactaacaa 200

 aagacatctt ctgttaacca acagccgcca ggcttcctgt tgaaataaat 250

 atatagcaac aaaggaaaaa aagaagcaaa acggaaatag tgcttaccag 300

 caccttagaa tgatgctgct caggaccagt ccaacactga atgtatctgc 350

 actgtgagga gaatgttcat agaagcctgt tgtgtgcata tttattcact 400

 ttttgttaaa tgttaaatcg tttagcacgg taatctgagt gcacagtatg 450

 tcatttcatt ccgtttgagt ttcttgtttt cgttaaatgt ctgcagagtt 500

 gctgcccctt tcttgaacta tgagtactgc aatcttttta attctcaata 550

 tgaatagagc tttttgagct ttaaatctaa ggggaactcg acaggcctgt 600

 ttggcatatg caatgaacat caagaaacca tcttgctgtg gaagcataat 650

 tatttttctt ctcccttttt gaaagatctt tccttttgat gccagttttc 700

 ttccttgttt acacaagttc aatttgaaag gaaaaggcaa tagtaagggt 750

 ttcaaaatgg cagagaaatt tgaaagtctc atgaacattc atggttttga 800

 tctgggttct aggtatatgg acttaaaacc attgggttgt ggaggcaatg 850

 gcttggtttt ttctgctgta gacaatgact gtgacaaaag agtagccatc 900

 aagaaaattg tccttactga tccccagagt gtcaaacatg ctctacgtga 950

 aatcaaaatt attagaagac ttgaccatga taacattgtg aaagtgtttg 1000

 agattcttgg tcccagtgga agccaattaa cagacgatgt gggctctctt 1050

 acggaactga acagtgttta cattgttcag gagtacatgg agacagactt 1100

 ggctaatgtg ctggagcagg gccctttact ggaagagcat gccaggcttt 1150

 tcatgtatca gctgctacgg gggctcaagt atattcactc tgcaaatgta 1200

 ctgcacagag atctcaaacc agctaatctt ttcattaata cggaagactt 1250

 ggtgctgaag ataggtgact ttggtcttgc acggatcatg gatcctcatt 1300

 attcccataa gggtcatctt tctgaaggat tggttactaa atggtacaga 1350

 tctccacgtc ttttactttc tcctaataat tatactaaag ccattgacat 1400

 gtgggctgca ggctgcatct ttgctgaaat gctgactggt aaaacccttt 1450

 ttgcaggtgc acatgaactt gaacagatgc agctgatttt agaatctatt 1500

 cctgttgtac atgaggaaga tcgtcaggag cttctcagcg taattccagt 1550

 ttacattaga aatgacatga ctgagccaca caaaccttta actcagctgc 1600

 ttccaggaat tagtcgagaa gcactggatt tcctggaaca aattttgaca 1650

 tttagcccca tggatcggtt aacagcagaa gaagcactct cccatcctta 1700

 catgagcata tattcttttc caatggatga gccaatttca agccatcctt 1750

 ttcatattga agatgaagtt gatgatattt tgcttatgga tgaaactcac 1800

 agtcacattt ataactggga aaggtatcat gattgtcagt tttcagagca 1850

 tgattggcct gtacataaca actttgatat tgatgaagtt cagcttgatc 1900

 caagagctct gtccgatgtc actgatgaag aagaagtaca agttgatccc 1950

 cgaaaatatt tggatggaga tcgggaaaag tatctggagg atcctgcttt 2000

 tgataccaat tactctactg agccttgttg gcaatactca gatcatcatg 2050

 aaaacaaata ttgtgatctg gagtgtagcc atacttgtaa ctacaaaacg 2100

 aggtcatcat catatttaga taacttagtt tggagagaga gtgaagttaa 2150

 ccattactat gaacccaagc ttattataga tctttccaat tggaaagaac 2200

 aaagcaaaga aaaatctgat aagaaaggca aatcaaaatg tgaaaggaat 2250

 ggattggtta aagcccagat agcgctagag gaagcatcac agcaactggc 2300

 tggaaaagaa agggaaaaga atcagggatt tgattttgat tcctttattg 2350

 caggaactat tcagcttagt tcccagcatg agcctactga tgttgttgat 2400

 aaattaaatg acttgaatag ctcagtgtcc caactagaat tgaaaagttt 2450

 gatatcaaag tcagtaagcc aagaaaaaca ggaaaaagga atggcaaatc 2500

 tggctcaatt agaagccttg taccagtctt cttgggacag ccagtttgtg 2550

 agtggtgggg aggactgttt tttcataaat cagttttgtg aggtaaggaa 2600

 ggatgaacaa gttgagaagg aaaacactta cactagttac ttggacaagt 2650

 tctttagcag gaaagaagat actgaaatgc tagaaactga gccagtagag 2700

 gatgggaagc ttggggagag aggacatgag gaaggatttc tgaacaacag 2750

 tggggagttc ctctttaaca agcagctcga gtccataggc atcccacagt 2800

 ttcacagtcc agttgggtca ccacttaagt caatacaggc cacattaaca 2850

 ccttctgcta tgaaatcttc ccctcaaatt cctcatcaaa catacagcag 2900

 cattctgaaa catctgaact aaaacactca gcagacattt atctttgtat 2950

 tcttcatgaa atgtgttttg tcttttttta ttactagtgt ttaagtcatt 3000

 ttttacttga atcagatggt gtcatttagt aaggatttta tgagttcttg 3050

 ttttttaaaa tccagacttt ctttttctac atgtgagata gttttcattt 3100

 taactggcat gtcatttgca cacaaaaata aagactagag caaaataatg 3150

 caacgcagga ggagaaaaga aatgcactaa gacaagaaca ttctctcata 3200

 gaacattgat ctgttttaca ggaaacaaac cttgccttga aatttacaca 3250

 gtgagactgt acataattgc atgaaaatag ctattttttt cctaagacat 3300

 ttttcattca tgaatatttt caagtttttc atactgtaca catttcttaa 3350

 aacacatgat accagcagca actgaaaatg aatgccgaat ttggtacaca 3400

 tgtgttatct acctcaaggt aacaagagta tgtggcaaaa catataccac 3450

 ccatagtgct tcacaaaatg cacttctatt tagccagcgt ttattgtagt 3500

 aaactattct taataaaact cactcactgt ttataaatgt tctggtatgc 3550

 attctttata gtgaagtgtt aatacatcac atcttattta ttttagcaaa 3600

 tcagtatatt ttctgtattt aattataaaa aattaactta gtttttaaaa 3650

 tttatttgca aatatacttt ttccatttgg cactatggtt tgttgcctac 3700

 ctagctgcat ctataatgtc agcttatcct aaggctgtcc acgtacttaa 3750

 tttacttaag tgttcatttt aagtaacgtg ctcactgtgt ataggaattt 3800

 gtattttgga ggtgcttgat ctatctacaa agaaaaatta attaggaatt 3850

 actttattat aaaatgctcc tagaagtctt aattgtgttt attttttaaa 3900

 aaaacaaatg ttagacttgt gtgcatggaa gtaattaagg tacatcatta 3950

 ttgtagtttg aaagttgtac atgataagac attttgtttt tactgtatgt 4000

 ttttactgaa tgatctattc cccatcccaa ggcaagcatg aataaaatta 4050

 ggttaaacgt agcatgtggc atcgcagtct cttagaattt gtttcatcta 4100

 ttttatttta ttgaatactg tctgtatctt tggttatcct gtttgaagaa 4150

 aaaggacaaa taaaacatgg ccagcaaata caaaaaaaaa aaa 4193

<210> 6185
<211> 721
<212> PRT
<213> Homo sapien

<400> 6185
 Met Ala Glu Lys Phe Glu Ser Leu Met Asn Ile His Gly Phe Asp
   1               5                  10                  15

 Leu Gly Ser Arg Tyr Met Asp Leu Lys Pro Leu Gly Cys Gly Gly
                  20                  25                  30

 Asn Gly Leu Val Phe Ser Ala Val Asp Asn Asp Cys Asp Lys Arg
                  35                  40                  45

 Val Ala Ile Lys Lys Ile Val Leu Thr Asp Pro Gln Ser Val Lys
                  50                  55                  60

 His Ala Leu Arg Glu Ile Lys Ile Ile Arg Arg Leu Asp His Asp
                  65                  70                  75

 Asn Ile Val Lys Val Phe Glu Ile Leu Gly Pro Ser Gly Ser Gln
                  80                  85                  90

 Leu Thr Asp Asp Val Gly Ser Leu Thr Glu Leu Asn Ser Val Tyr
                  95                 100                 105

 Ile Val Gln Glu Tyr Met Glu Thr Asp Leu Ala Asn Val Leu Glu
                 110                 115                 120

 Gln Gly Pro Leu Leu Glu Glu His Ala Arg Leu Phe Met Tyr Gln
                 125                 130                 135

 Leu Leu Arg Gly Leu Lys Tyr Ile His Ser Ala Asn Val Leu His
                 140                 145                 150

 Arg Asp Leu Lys Pro Ala Asn Leu Phe Ile Asn Thr Glu Asp Leu
                 155                 160                 165

 Val Leu Lys Ile Gly Asp Phe Gly Leu Ala Arg Ile Met Asp Pro
                 170                 175                 180

 His Tyr Ser His Lys Gly His Leu Ser Glu Gly Leu Val Thr Lys
                 185                 190                 195

 Trp Tyr Arg Ser Pro Arg Leu Leu Leu Ser Pro Asn Asn Tyr Thr
                 200                 205                 210

 Lys Ala Ile Asp Met Trp Ala Ala Gly Cys Ile Phe Ala Glu Met
                 215                 220                 225

 Leu Thr Gly Lys Thr Leu Phe Ala Gly Ala His Glu Leu Glu Gln
                 230                 235                 240

 Met Gln Leu Ile Leu Glu Ser Ile Pro Val Val His Glu Glu Asp
                 245                 250                 255

 Arg Gln Glu Leu Leu Ser Val Ile Pro Val Tyr Ile Arg Asn Asp
                 260                 265                 270

 Met Thr Glu Pro His Lys Pro Leu Thr Gln Leu Leu Pro Gly Ile
                 275                 280                 285

 Ser Arg Glu Ala Leu Asp Phe Leu Glu Gln Ile Leu Thr Phe Ser
                 290                 295                 300

 Pro Met Asp Arg Leu Thr Ala Glu Glu Ala Leu Ser His Pro Tyr
                 305                 310                 315

 Met Ser Ile Tyr Ser Phe Pro Met Asp Glu Pro Ile Ser Ser His
                 320                 325                 330

 Pro Phe His Ile Glu Asp Glu Val Asp Asp Ile Leu Leu Met Asp
                 335                 340                 345

 Glu Thr His Ser His Ile Tyr Asn Trp Glu Arg Tyr His Asp Cys
                 350                 355                 360

 Gln Phe Ser Glu His Asp Trp Pro Val His Asn Asn Phe Asp Ile
                 365                 370                 375

 Asp Glu Val Gln Leu Asp Pro Arg Ala Leu Ser Asp Val Thr Asp
                 380                 385                 390

 Glu Glu Glu Val Gln Val Asp Pro Arg Lys Tyr Leu Asp Gly Asp
                 395                 400                 405

 Arg Glu Lys Tyr Leu Glu Asp Pro Ala Phe Asp Thr Asn Tyr Ser
                 410                 415                 420

 Thr Glu Pro Cys Trp Gln Tyr Ser Asp His His Glu Asn Lys Tyr
                 425                 430                 435

 Cys Asp Leu Glu Cys Ser His Thr Cys Asn Tyr Lys Thr Arg Ser
                 440                 445                 450

 Ser Ser Tyr Leu Asp Asn Leu Val Trp Arg Glu Ser Glu Val Asn
                 455                 460                 465

 His Tyr Tyr Glu Pro Lys Leu Ile Ile Asp Leu Ser Asn Trp Lys
                 470                 475                 480

 Glu Gln Ser Lys Glu Lys Ser Asp Lys Lys Gly Lys Ser Lys Cys
                 485                 490                 495

 Glu Arg Asn Gly Leu Val Lys Ala Gln Ile Ala Leu Glu Glu Ala
                 500                 505                 510

 Ser Gln Gln Leu Ala Gly Lys Glu Arg Glu Lys Asn Gln Gly Phe
                 515                 520                 525

 Asp Phe Asp Ser Phe Ile Ala Gly Thr Ile Gln Leu Ser Ser Gln
                 530                 535                 540

 His Glu Pro Thr Asp Val Val Asp Lys Leu Asn Asp Leu Asn Ser
                 545                 550                 555

 Ser Val Ser Gln Leu Glu Leu Lys Ser Leu Ile Ser Lys Ser Val
                 560                 565                 570

 Ser Gln Glu Lys Gln Glu Lys Gly Met Ala Asn Leu Ala Gln Leu
                 575                 580                 585

 Glu Ala Leu Tyr Gln Ser Ser Trp Asp Ser Gln Phe Val Ser Gly
                 590                 595                 600

 Gly Glu Asp Cys Phe Phe Ile Asn Gln Phe Cys Glu Val Arg Lys
                 605                 610                 615

 Asp Glu Gln Val Glu Lys Glu Asn Thr Tyr Thr Ser Tyr Leu Asp
                 620                 625                 630

 Lys Phe Phe Ser Arg Lys Glu Asp Thr Glu Met Leu Glu Thr Glu
                 635                 640                 645

 Pro Val Glu Asp Gly Lys Leu Gly Glu Arg Gly His Glu Glu Gly
                 650                 655                 660

 Phe Leu Asn Asn Ser Gly Glu Phe Leu Phe Asn Lys Gln Leu Glu
                 665                 670                 675

 Ser Ile Gly Ile Pro Gln Phe His Ser Pro Val Gly Ser Pro Leu
                 680                 685                 690

 Lys Ser Ile Gln Ala Thr Leu Thr Pro Ser Ala Met Lys Ser Ser
                 695                 700                 705

 Pro Gln Ile Pro His Gln Thr Tyr Ser Ser Ile Leu Lys His Leu
                 710                 715                 720

 Asn


<210> 6186
<211> 3237
<212> DNA
<213> Homo sapien

<400> 6186
 gcgaagtgaa gggtggccca ggtggggcca ggctgactga atgtatctcc 50

 tagctatgga ctaaataata catgggggga aataaacaag tattcatgag 100

 ggtgaaaatg tgacccagca ggaaaattac aactattttc aattgacgtt 150

 gaataggatg agtcatggaa tttaagtgat ttactgaaga ttatactact 200

 ggtagataga agagctaaag aaagatggat actatgatgc tgaatgtgcg 250

 gaatctgttt gagcagcttg tgcgccgggt ggagattctc agtgaaggaa 300

 atgaagtcca atttatccag ttggcgaagg actttgagga tttccgtaaa 350

 aagtggcaga ggactgacca tgagctgggg aaatacaagg atcttttgat 400

 gaaagcagag actgagcgaa gtgctctgga tgttaagctg aagcatgcac 450

 gtaatcaggt ggatgtagag atcaaacgga gacagagagc tgaggctgac 500

 tgcgaaaagc tggaacgaca gattcagctg attcgagaga tgctcatgtg 550

 tgacacatct ggcagcattc aactaagcga ggagcaaaaa tcagctctgg 600

 cttttctcaa cagaggccaa ccatccagca gcaatgctgg gaacaaaaga 650

 ctatcaacca ttgatgaatc tggttccatt ttatcagata tcagctttga 700

 caagactgat gaatcactgg attgggactc ttctttggtg aagactttca 750

 aactgaagaa gagagaaaag aggcgctcta ctagccgaca gtttgttgat 800

 ggtccccctg gacctgtaaa gaaaactcgt tccattggct ctgcagtaga 850

 ccaggggaat gaatccatag ttgcaaaaac tacagtgact gttcccaatg 900

 atggcgggcc catcgaagct gtgtccacta ttgagactgt gccatattgg 950

 accaggagcc gaaggaaaac aggtacttta caaccttgga acagtgactc 1000

 caccctgaac agcaggcagc tggagccaag aactgagaca gacagtgtgg 1050

 gcacgccaca gagtaatgga gggatgcgcc tgcatgactt tgtttctaag 1100

 acggttatta aacctgaatc ctgtgttcca tgtggaaagc ggataaaatt 1150

 tggcaaatta tctctgaagt gtcgagactg tcgtgtggtc tctcatccag 1200

 aatgtcggga ccgctgtccc cttccctgca ttcctaccct gataggaaca 1250

 cctgtcaaga ttggagaggg aatgctggca gactttgtgt cccagacttc 1300

 tccaatgatc ccctccattg ttgtgcattg tgtaaatgag attgagcaaa 1350

 gaggtctgac tgagacaggc ctgtatagga tctctggctg tgaccgcaca 1400

 gtaaaagagc tgaaagagaa attcctcaga gtgaaaactg tacccctcct 1450

 cagcaaagtg gatgatatcc atgctatctg tagccttcta aaagactttc 1500

 ttcgaaacct caaagaacct cttctgacct ttcgccttaa cagagccttt 1550

 atggaagcag cagaaatcac agatgaagac aacagcatag ctgccatgta 1600

 ccaagctgtt ggtgaactgc cccaggccaa cagggacaca ttagctttcc 1650

 tcatgattca cttgcagaga gtggctcaga gtccacatac taaaatggat 1700

 gttgccaatc tggctaaagt ctttggccct acaatagtgg cccatgctgt 1750

 gcccaatcca gacccagtga caatgttaca ggacatcaag cgtcaaccca 1800

 aggtggttga gcgcctgctt tccttgcctc tggagtattg gagtcagttc 1850

 atgatggtgg agcaagagaa cattgacccc ctacatgtca ttgaaaactc 1900

 aaatgccttt tcaacaccac agacaccaga tattaaagtg agtttactgg 1950

 gacctgtgac cactcctgaa catcagcttc tcaagactcc ttcatctagt 2000

 tccctgtcac agagagtccg ttccaccctc accaagaaca ctcctagatt 2050

 tgggagcaaa agcaagtctg ccactaacct aggacgacaa ggcaactttt 2100

 ttgcttctcc aatgctcaag tgaagtcaca tctgcctgtt acttcccagc 2150

 attgactgac tataagaaag gacacatctg tactctgctc tgcagcctcc 2200

 tgtactcatt actactttta gcattctcca ggcttttact caagtttaat 2250

 tgtgcatgag ggttttatta aaactatata tatctcccct tccttctcct 2300

 caagtcacat aatatcagca ctttgtgctg gtcattgttg ggagctttta 2350

 gatgagacat ctttccaggg gtagaagggt tagtatggaa ttggttgtga 2400

 ttctttttgg ggaagggggt tattgttcct ttggcttaaa gccaaatgct 2450

 gctcatagaa tgatctttct ctagtttcat ttagaactga tttccgtgag 2500

 acaatgacag aaaccctacc tatctgataa gattagcttg tctcagggtg 2550

 ggaagtggga gggcagggca aagaaaggat tagaccagag gatttaggat 2600

 gcctccttct aagaaccaga agttctcatt ccccattatg aactgagcta 2650

 taatatggag ctttcataaa aatgggatgc attgaggaca gaactagtga 2700

 tgggagtatg cgtagctttg atttggatga ttaggtcttt aatagtgttg 2750

 agtggcacaa ccttgtaaat gtgaaagtac aactcgtatt tatctctgat 2800

 gtgccgctgg ctgaactttg ggttcatttg gggtcaaagc cagtttttct 2850

 tttaaaattg aattcattct gatgcttggc ccccataccc ccaaccttgt 2900

 ccagtggagc ccaacttcta aaggtcaata tatcatcctt tggcatccca 2950

 actaacaata aagagtaggc tataagggaa gattgtcaat attttgtggt 3000

 aagaaaagct acagtcattt tttctttgca ctttggatgc tgaaattttt 3050

 cccatggaac atagccacat ctagatagat gtgagctttt tcttctgtta 3100

 aaattattct taatgtctgt aaaaacgatt ttcttctgta gaatgtttga 3150

 cttcgtattg acccttatct gtaaaacacc tatttgggat aatatttgga 3200

 aaaaaagtaa atagcttttt caaaatgaaa aaaaaaa 3237

<210> 6187
<211> 632
<212> PRT
<213> Homo sapien

<400> 6187
 Met Asp Thr Met Met Leu Asn Val Arg Asn Leu Phe Glu Gln Leu
   1               5                  10                  15

 Val Arg Arg Val Glu Ile Leu Ser Glu Gly Asn Glu Val Gln Phe
                  20                  25                  30

 Ile Gln Leu Ala Lys Asp Phe Glu Asp Phe Arg Lys Lys Trp Gln
                  35                  40                  45

 Arg Thr Asp His Glu Leu Gly Lys Tyr Lys Asp Leu Leu Met Lys
                  50                  55                  60

 Ala Glu Thr Glu Arg Ser Ala Leu Asp Val Lys Leu Lys His Ala
                  65                  70                  75

 Arg Asn Gln Val Asp Val Glu Ile Lys Arg Arg Gln Arg Ala Glu
                  80                  85                  90

 Ala Asp Cys Glu Lys Leu Glu Arg Gln Ile Gln Leu Ile Arg Glu
                  95                 100                 105

 Met Leu Met Cys Asp Thr Ser Gly Ser Ile Gln Leu Ser Glu Glu
                 110                 115                 120

 Gln Lys Ser Ala Leu Ala Phe Leu Asn Arg Gly Gln Pro Ser Ser
                 125                 130                 135

 Ser Asn Ala Gly Asn Lys Arg Leu Ser Thr Ile Asp Glu Ser Gly
                 140                 145                 150

 Ser Ile Leu Ser Asp Ile Ser Phe Asp Lys Thr Asp Glu Ser Leu
                 155                 160                 165

 Asp Trp Asp Ser Ser Leu Val Lys Thr Phe Lys Leu Lys Lys Arg
                 170                 175                 180

 Glu Lys Arg Arg Ser Thr Ser Arg Gln Phe Val Asp Gly Pro Pro
                 185                 190                 195

 Gly Pro Val Lys Lys Thr Arg Ser Ile Gly Ser Ala Val Asp Gln
                 200                 205                 210

 Gly Asn Glu Ser Ile Val Ala Lys Thr Thr Val Thr Val Pro Asn
                 215                 220                 225

 Asp Gly Gly Pro Ile Glu Ala Val Ser Thr Ile Glu Thr Val Pro
                 230                 235                 240

 Tyr Trp Thr Arg Ser Arg Arg Lys Thr Gly Thr Leu Gln Pro Trp
                 245                 250                 255

 Asn Ser Asp Ser Thr Leu Asn Ser Arg Gln Leu Glu Pro Arg Thr
                 260                 265                 270

 Glu Thr Asp Ser Val Gly Thr Pro Gln Ser Asn Gly Gly Met Arg
                 275                 280                 285

 Leu His Asp Phe Val Ser Lys Thr Val Ile Lys Pro Glu Ser Cys
                 290                 295                 300

 Val Pro Cys Gly Lys Arg Ile Lys Phe Gly Lys Leu Ser Leu Lys
                 305                 310                 315

 Cys Arg Asp Cys Arg Val Val Ser His Pro Glu Cys Arg Asp Arg
                 320                 325                 330

 Cys Pro Leu Pro Cys Ile Pro Thr Leu Ile Gly Thr Pro Val Lys
                 335                 340                 345

 Ile Gly Glu Gly Met Leu Ala Asp Phe Val Ser Gln Thr Ser Pro
                 350                 355                 360

 Met Ile Pro Ser Ile Val Val His Cys Val Asn Glu Ile Glu Gln
                 365                 370                 375

 Arg Gly Leu Thr Glu Thr Gly Leu Tyr Arg Ile Ser Gly Cys Asp
                 380                 385                 390

 Arg Thr Val Lys Glu Leu Lys Glu Lys Phe Leu Arg Val Lys Thr
                 395                 400                 405

 Val Pro Leu Leu Ser Lys Val Asp Asp Ile His Ala Ile Cys Ser
                 410                 415                 420

 Leu Leu Lys Asp Phe Leu Arg Asn Leu Lys Glu Pro Leu Leu Thr
                 425                 430                 435

 Phe Arg Leu Asn Arg Ala Phe Met Glu Ala Ala Glu Ile Thr Asp
                 440                 445                 450

 Glu Asp Asn Ser Ile Ala Ala Met Tyr Gln Ala Val Gly Glu Leu
                 455                 460                 465

 Pro Gln Ala Asn Arg Asp Thr Leu Ala Phe Leu Met Ile His Leu
                 470                 475                 480

 Gln Arg Val Ala Gln Ser Pro His Thr Lys Met Asp Val Ala Asn
                 485                 490                 495

 Leu Ala Lys Val Phe Gly Pro Thr Ile Val Ala His Ala Val Pro
                 500                 505                 510

 Asn Pro Asp Pro Val Thr Met Leu Gln Asp Ile Lys Arg Gln Pro
                 515                 520                 525

 Lys Val Val Glu Arg Leu Leu Ser Leu Pro Leu Glu Tyr Trp Ser
                 530                 535                 540

 Gln Phe Met Met Val Glu Gln Glu Asn Ile Asp Pro Leu His Val
                 545                 550                 555

 Ile Glu Asn Ser Asn Ala Phe Ser Thr Pro Gln Thr Pro Asp Ile
                 560                 565                 570

 Lys Val Ser Leu Leu Gly Pro Val Thr Thr Pro Glu His Gln Leu
                 575                 580                 585

 Leu Lys Thr Pro Ser Ser Ser Ser Leu Ser Gln Arg Val Arg Ser
                 590                 595                 600

 Thr Leu Thr Lys Asn Thr Pro Arg Phe Gly Ser Lys Ser Lys Ser
                 605                 610                 615

 Ala Thr Asn Leu Gly Arg Gln Gly Asn Phe Phe Ala Ser Pro Met
                 620                 625                 630

 Leu Lys


<210> 6188
<211> 2425
<212> DNA
<213> Homo sapien

<400> 6188
 atgtggtgga gagttctcag cttgctggca tggttcccct tgcaagaggc 50

 ctctctgact aaccacacag aaaccatcac cgtggaggaa ggccagacgc 100

 tcactctaaa gtgtgtcact tctctgagga agaactcctc cctccagtgg 150

 ctgaccccct cagggttcac cattttttta aatgagtatc ctgctttaaa 200

 aaattccaaa taccagcttc ttcatcactc ggccaatcag ctctccatca 250

 ctgtgcctaa cgtaaccctg caagatgaag gcgtgtacaa gtgcttacat 300

 tacagcgact ctgtaagcac aaaggaagtg aaagtgattg tgctggcaac 350

 tcctttcaag ccaatcctgg aagcttcagt tatcagaaag caaaatggag 400

 aagaacatgt tgtactcatg tgctccacca tgagaagcaa gccccctccg 450

 cagataacct ggctacttgg gaatagcatg gaagtgtccg gtggaacgct 500

 ccatgaattt gaaactgatg ggaagaaatg taatactacc agcactctca 550

 taatccacac ttatggcaaa aattcaacgg tggactgcat tatccgacac 600

 agaggcctgc aagggagaaa actagtagca cccttccggt ttgaagattt 650

 ggttactgat gaagagacag cttcagatgc tctggagaga aactctctat 700

 cctctcaaga cccacagcag cccaccagta ctgtctcagt aacggaagat 750

 tctagtacat cggagattga caaggaagag aaagaacaaa ccactcaaga 800

 tcctgacttg accaccgaag caaatcctca gtatttagga ctggcaagaa 850

 agaaaagtgg catcctgctg ctcacgctgg tgtccttcct cattttcata 900

 ctcttcatca tagtccagct cttcatcatg aagctgagga aagcacatgt 950

 gatatggaag agagaaaacg aagtttcaga acacacacta gaaagttaca 1000

 gatcaaggtc aaataatgaa gaaacatcat ctgaagagaa aaatggccaa 1050

 tcttcccacc ctatgcgttg catgaactac atcacaaagt tgtactcaga 1100

 agcaaaaaca aagaggaagg aaaatgtaca acattcaaaa ttagaagaaa 1150

 agcacatcca agtaccagag agtattgtgt agtgctctct gcaatggaac 1200

 atgtgatttc agggttgccg cagtgtcacc tcagtggacc agcctggggg 1250

 aaggagctta attgctgaga cattaataat gacctcttag tgcaatgcaa 1300

 gatggtgtcc tcggataatg atctgccccg gagctagggc agcaacatga 1350

 ggaccaaacc atgcacataa agcttgtagt ttaaaaaaga aaagcaaaaa 1400

 aataattatg cctgacacta cttcagagca ggaggattct acgaagcctt 1450

 ggggatcagg gtcagtgtga gcagctaaca tcctacctca aatggaacag 1500

 gattttttga tgctttgctc taatggaact gttttaaaaa tttttttttc 1550

 tttttaatat tttcttctgg tcacaaaata aagaaatttg ggatgcaaag 1600

 tacctaaaga tctctgatcc taagaagtta cttctggcca ggcgcggtgg 1650

 ctcatgcctg taatcctagc actttgggag gctgaggtag gcagatcact 1700

 tgaggtcagg agttggagac cagcctggcc aacatagtga aaccccgtct 1750

 ctactaaaaa tgcaaaaatt agccaggcgt agtggtgcgc acctgtagtc 1800

 tcagatactt gggaggctga gggtggagaa tcgcttgaac ctgggaggtg 1850

 gagattgcag tgagtcaaga tctcaccact gaactccagc ctgggcgaca 1900

 gagggagact ctgtctcaaa aaaaaagaag ttacttccaa gacagacttt 1950

 taacatgtaa ccagcacaaa gcaatgtcag ggaggagtga tacatgacaa 2000

 taaatgagtc agatgagcaa gaaggcccca gaacccatgc cccaaggcac 2050

 aaagaggagc tcagggtagg cccaaagatt cgaattcctt agattactaa 2100

 atcacatgag cggaccttgt ctgtcagata agatttttac ctggaaattc 2150

 catgaccaat acatgtgcaa aagaaaatga tgggttgaat ttactgatta 2200

 ttgacctaat ggatggcttt ttaaaatgtt ttaataaaaa gcagaataga 2250

 tgtttgtttt tctagtggtt ataccaagct atacttcctg ttttcacgtg 2300

 tgaaagtaac atgggacatg cctttctttt ccgatcagtt tatttaagct 2350

 atacagcaaa ctttggcatt tatgtggagc atttctcatt gttggaatct 2400

 gaataaacca attacaaaat aaaaa 2425

<210> 6189
<211> 393
<212> PRT
<213> Homo sapien

<400> 6189
 Met Trp Trp Arg Val Leu Ser Leu Leu Ala Trp Phe Pro Leu Gln
   1               5                  10                  15

 Glu Ala Ser Leu Thr Asn His Thr Glu Thr Ile Thr Val Glu Glu
                  20                  25                  30

 Gly Gln Thr Leu Thr Leu Lys Cys Val Thr Ser Leu Arg Lys Asn
                  35                  40                  45

 Ser Ser Leu Gln Trp Leu Thr Pro Ser Gly Phe Thr Ile Phe Leu
                  50                  55                  60

 Asn Glu Tyr Pro Ala Leu Lys Asn Ser Lys Tyr Gln Leu Leu His
                  65                  70                  75

 His Ser Ala Asn Gln Leu Ser Ile Thr Val Pro Asn Val Thr Leu
                  80                  85                  90

 Gln Asp Glu Gly Val Tyr Lys Cys Leu His Tyr Ser Asp Ser Val
                  95                 100                 105

 Ser Thr Lys Glu Val Lys Val Ile Val Leu Ala Thr Pro Phe Lys
                 110                 115                 120

 Pro Ile Leu Glu Ala Ser Val Ile Arg Lys Gln Asn Gly Glu Glu
                 125                 130                 135

 His Val Val Leu Met Cys Ser Thr Met Arg Ser Lys Pro Pro Pro
                 140                 145                 150

 Gln Ile Thr Trp Leu Leu Gly Asn Ser Met Glu Val Ser Gly Gly
                 155                 160                 165

 Thr Leu His Glu Phe Glu Thr Asp Gly Lys Lys Cys Asn Thr Thr
                 170                 175                 180

 Ser Thr Leu Ile Ile His Thr Tyr Gly Lys Asn Ser Thr Val Asp
                 185                 190                 195

 Cys Ile Ile Arg His Arg Gly Leu Gln Gly Arg Lys Leu Val Ala
                 200                 205                 210

 Pro Phe Arg Phe Glu Asp Leu Val Thr Asp Glu Glu Thr Ala Ser
                 215                 220                 225

 Asp Ala Leu Glu Arg Asn Ser Leu Ser Ser Gln Asp Pro Gln Gln
                 230                 235                 240

 Pro Thr Ser Thr Val Ser Val Thr Glu Asp Ser Ser Thr Ser Glu
                 245                 250                 255

 Ile Asp Lys Glu Glu Lys Glu Gln Thr Thr Gln Asp Pro Asp Leu
                 260                 265                 270

 Thr Thr Glu Ala Asn Pro Gln Tyr Leu Gly Leu Ala Arg Lys Lys
                 275                 280                 285

 Ser Gly Ile Leu Leu Leu Thr Leu Val Ser Phe Leu Ile Phe Ile
                 290                 295                 300

 Leu Phe Ile Ile Val Gln Leu Phe Ile Met Lys Leu Arg Lys Ala
                 305                 310                 315

 His Val Ile Trp Lys Arg Glu Asn Glu Val Ser Glu His Thr Leu
                 320                 325                 330

 Glu Ser Tyr Arg Ser Arg Ser Asn Asn Glu Glu Thr Ser Ser Glu
                 335                 340                 345

 Glu Lys Asn Gly Gln Ser Ser His Pro Met Arg Cys Met Asn Tyr
                 350                 355                 360

 Ile Thr Lys Leu Tyr Ser Glu Ala Lys Thr Lys Arg Lys Glu Asn
                 365                 370                 375

 Val Gln His Ser Lys Leu Glu Glu Lys His Ile Gln Val Pro Glu
                 380                 385                 390

 Ser Ile Val


<210> 6190
<211> 1677
<212> DNA
<213> Homo sapien

<400> 6190
 cgggggtttt gatcttcttc cccttctttt cttccccttc ttctttcctt 50

 cctccctccc tctctcattt cccttctcct tctccctcag tctccacatt 100

 caacattgac aagtccattc agaaaagcaa gctgcttctg gttgggccca 150

 gacctgcctt gaggagcctg tagagttaaa aaatgaaccc cacggatata 200

 gcagatacca ccctcgatga aagcatatac agcaattact atctgtatga 250

 aagtatcccc aagccttgca ccaaagaagg catcaaggca tttggggagc 300

 tcttcctgcc cccactgtat tccttggttt ttgtatttgg tctgcttgga 350

 aattctgtgg tggttctggt cctgttcaaa tacaagcggc tcaggtccat 400

 gactgatgtg tacctgctca accttgccat ctcggatctg ctcttcgtgt 450

 tttccctccc tttttggggc tactatgcag cagaccagtg ggtttttggg 500

 ctaggtctgt gcaagatgat ttcctggatg tacttggtgg gcttttacag 550

 tggcatattc tttgtcatgc tcatgagcat tgatagatac ctggcgatag 600

 tgcacgcggt gttttccttg agggcaagga ccttgactta tggggtcatc 650

 accagtttgg ctacatggtc agtggctgtg ttcgcctccc ttcctggctt 700

 tctgttcagc acttgttata ctgagcgcaa ccatacctac tgcaaaacca 750

 agtactctct caactccacg acgtggaagg ttctcagctc cctggaaatc 800

 aacattctcg gattggtgat ccccttaggg atcatgctgt tttgctactc 850

 catgatcatc aggaccttgc agcattgtaa aaatgagaag aagaacaagg 900

 cggtgaagat gatctttgcc gtggtggtcc tcttccttgg gttctggaca 950

 ccttacaaca tagtgctctt cctagagacc ctggtggagc tagaagtcct 1000

 tcaggactgc acctttgaaa gatacttgga ctatgccatc caggccacag 1050

 aaactctggc ttttgttcac tgctgcctta atcccatcat ctactttttt 1100

 ctgggggaga aatttcgcaa gtacatccta cagctcttca aaacctgcag 1150

 gggccttttt gtgctctgcc aatactgtgg gctcctccaa atttactctg 1200

 ctgacacccc cagctcatct tacacgcagt ccaccatgga tcatgatctt 1250

 catgatgctc tgtaggaaaa atgaaatggt gaaatgcaga gtcaatgaac 1300

 ttttccacat tcagagctta ctttaaaatt ggtattttta ggtaagagat 1350

 ccctgagcca gtgtcaggag gaaggcttac acccacagtg gaaagacagc 1400

 ttctcatcct gcaggcagct ttttctctcc cactagacaa gtccagcctg 1450

 gcaagggttc acctgggctg aggcatcctt cctcacacca ggcttgcctg 1500

 caggcatgag tcagtctgat gagaactctg agcagtgctt gaatgaagtt 1550

 gtaggtaata ttgcaaggca aagactattc ccttctaacc tgaactgatg 1600

 ggtttctcca gagggaattg cagagtactg gctgatggag taaatcgcta 1650

 ccttttgctg tggcaaatgg gcccccg 1677

<210> 6191
<211> 360
<212> PRT
<213> Homo sapien

<400> 6191
 Met Asn Pro Thr Asp Ile Ala Asp Thr Thr Leu Asp Glu Ser Ile
   1               5                  10                  15

 Tyr Ser Asn Tyr Tyr Leu Tyr Glu Ser Ile Pro Lys Pro Cys Thr
                  20                  25                  30

 Lys Glu Gly Ile Lys Ala Phe Gly Glu Leu Phe Leu Pro Pro Leu
                  35                  40                  45

 Tyr Ser Leu Val Phe Val Phe Gly Leu Leu Gly Asn Ser Val Val
                  50                  55                  60

 Val Leu Val Leu Phe Lys Tyr Lys Arg Leu Arg Ser Met Thr Asp
                  65                  70                  75

 Val Tyr Leu Leu Asn Leu Ala Ile Ser Asp Leu Leu Phe Val Phe
                  80                  85                  90

 Ser Leu Pro Phe Trp Gly Tyr Tyr Ala Ala Asp Gln Trp Val Phe
                  95                 100                 105

 Gly Leu Gly Leu Cys Lys Met Ile Ser Trp Met Tyr Leu Val Gly
                 110                 115                 120

 Phe Tyr Ser Gly Ile Phe Phe Val Met Leu Met Ser Ile Asp Arg
                 125                 130                 135

 Tyr Leu Ala Ile Val His Ala Val Phe Ser Leu Arg Ala Arg Thr
                 140                 145                 150

 Leu Thr Tyr Gly Val Ile Thr Ser Leu Ala Thr Trp Ser Val Ala
                 155                 160                 165

 Val Phe Ala Ser Leu Pro Gly Phe Leu Phe Ser Thr Cys Tyr Thr
                 170                 175                 180

 Glu Arg Asn His Thr Tyr Cys Lys Thr Lys Tyr Ser Leu Asn Ser
                 185                 190                 195

 Thr Thr Trp Lys Val Leu Ser Ser Leu Glu Ile Asn Ile Leu Gly
                 200                 205                 210

 Leu Val Ile Pro Leu Gly Ile Met Leu Phe Cys Tyr Ser Met Ile
                 215                 220                 225

 Ile Arg Thr Leu Gln His Cys Lys Asn Glu Lys Lys Asn Lys Ala
                 230                 235                 240

 Val Lys Met Ile Phe Ala Val Val Val Leu Phe Leu Gly Phe Trp
                 245                 250                 255

 Thr Pro Tyr Asn Ile Val Leu Phe Leu Glu Thr Leu Val Glu Leu
                 260                 265                 270

 Glu Val Leu Gln Asp Cys Thr Phe Glu Arg Tyr Leu Asp Tyr Ala
                 275                 280                 285

 Ile Gln Ala Thr Glu Thr Leu Ala Phe Val His Cys Cys Leu Asn
                 290                 295                 300

 Pro Ile Ile Tyr Phe Phe Leu Gly Glu Lys Phe Arg Lys Tyr Ile
                 305                 310                 315

 Leu Gln Leu Phe Lys Thr Cys Arg Gly Leu Phe Val Leu Cys Gln
                 320                 325                 330

 Tyr Cys Gly Leu Leu Gln Ile Tyr Ser Ala Asp Thr Pro Ser Ser
                 335                 340                 345

 Ser Tyr Thr Gln Ser Thr Met Asp His Asp Leu His Asp Ala Leu
                 350                 355                 360

<210> 6192
<211> 1083
<212> DNA
<213> Homo sapien

<400> 6192
 atggacccag aagaaacttc agtttatttg gattattact atgctacgag 50

 cccaaactct gacatcaggg agacccactc ccatgttcct tacacctctg 100

 tcttccttcc agtcttttac acagctgtgt tcctgactgg agtgctgggg 150

 aaccttgttc tcatgggagc gttgcatttc aaacccggca gccgaagact 200

 gatcgacatc tttatcatca atctggctgc ctctgacttc atttttcttg 250

 tcacattgcc tctctgggtg gataaagaag catctctagg actgtggagg 300

 acgggctcct tcctgtgcaa agggagctcc tacatgatct ccgtcaatat 350

 gcactgcagt gtcctcctgc tcacttgcat gagtgttgac cgctacctgg 400

 ccattgtgtg gccagtcgta tccaggaaat tcagaaggac agactgtgca 450

 tatgtagtct gtgccagcat ctggtttatc tcctgcctgc tggggttgcc 500

 tactcttctg tccagggagc tcacgctgat tgatgataag ccatactgtg 550

 cagagaaaaa ggcaactcca attaaactca tatggtccct ggtggcctta 600

 attttcacct tttttgtccc tttgttgagc attgtgacct gctactgttg 650

 cattgcaagg aagctgtgtg cccattacca gcaatcagga aagcacaaca 700

 aaaagctgaa gaaatctata aagatcatct ttattgtcgt ggcagccttt 750

 cttgtctcct ggctgccctt caatactttc aagttcctgg ccattgtctc 800

 tgggttgcgg caagaacact atttaccctc agctattctt cagcttggta 850

 tggaggtgag tggacccttg gcatttgcca acagctgtgt caaccctttc 900

 atttactata tcttcgacag ctacatccgc cgggccattg tccactgctt 950

 gtgcccttgc ctgaaaaact atgactttgg gagtagcact gagacatcag 1000

 atagtcacct cactaaggct ctctccacct tcattcatgc agaagatttt 1050

 gccaggagga ggaagaggtc tgtgtcactc taa 1083

<210> 6193
<211> 360
<212> PRT
<213> Homo sapien

<400> 6193
 Met Asp Pro Glu Glu Thr Ser Val Tyr Leu Asp Tyr Tyr Tyr Ala
   1               5                  10                  15

 Thr Ser Pro Asn Ser Asp Ile Arg Glu Thr His Ser His Val Pro
                  20                  25                  30

 Tyr Thr Ser Val Phe Leu Pro Val Phe Tyr Thr Ala Val Phe Leu
                  35                  40                  45

 Thr Gly Val Leu Gly Asn Leu Val Leu Met Gly Ala Leu His Phe
                  50                  55                  60

 Lys Pro Gly Ser Arg Arg Leu Ile Asp Ile Phe Ile Ile Asn Leu
                  65                  70                  75

 Ala Ala Ser Asp Phe Ile Phe Leu Val Thr Leu Pro Leu Trp Val
                  80                  85                  90

 Asp Lys Glu Ala Ser Leu Gly Leu Trp Arg Thr Gly Ser Phe Leu
                  95                 100                 105

 Cys Lys Gly Ser Ser Tyr Met Ile Ser Val Asn Met His Cys Ser
                 110                 115                 120

 Val Leu Leu Leu Thr Cys Met Ser Val Asp Arg Tyr Leu Ala Ile
                 125                 130                 135

 Val Trp Pro Val Val Ser Arg Lys Phe Arg Arg Thr Asp Cys Ala
                 140                 145                 150

 Tyr Val Val Cys Ala Ser Ile Trp Phe Ile Ser Cys Leu Leu Gly
                 155                 160                 165

 Leu Pro Thr Leu Leu Ser Arg Glu Leu Thr Leu Ile Asp Asp Lys
                 170                 175                 180

 Pro Tyr Cys Ala Glu Lys Lys Ala Thr Pro Ile Lys Leu Ile Trp
                 185                 190                 195

 Ser Leu Val Ala Leu Ile Phe Thr Phe Phe Val Pro Leu Leu Ser
                 200                 205                 210

 Ile Val Thr Cys Tyr Cys Cys Ile Ala Arg Lys Leu Cys Ala His
                 215                 220                 225

 Tyr Gln Gln Ser Gly Lys His Asn Lys Lys Leu Lys Lys Ser Ile
                 230                 235                 240

 Lys Ile Ile Phe Ile Val Val Ala Ala Phe Leu Val Ser Trp Leu
                 245                 250                 255

 Pro Phe Asn Thr Phe Lys Phe Leu Ala Ile Val Ser Gly Leu Arg
                 260                 265                 270

 Gln Glu His Tyr Leu Pro Ser Ala Ile Leu Gln Leu Gly Met Glu
                 275                 280                 285

 Val Ser Gly Pro Leu Ala Phe Ala Asn Ser Cys Val Asn Pro Phe
                 290                 295                 300

 Ile Tyr Tyr Ile Phe Asp Ser Tyr Ile Arg Arg Ala Ile Val His
                 305                 310                 315

 Cys Leu Cys Pro Cys Leu Lys Asn Tyr Asp Phe Gly Ser Ser Thr
                 320                 325                 330

 Glu Thr Ser Asp Ser His Leu Thr Lys Ala Leu Ser Thr Phe Ile
                 335                 340                 345

 His Ala Glu Asp Phe Ala Arg Arg Arg Lys Arg Ser Val Ser Leu
                 350                 355                 360

<210> 6194
<211> 1026
<212> DNA
<213> Homo sapien

<400> 6194
 gagagctggc tgcgccgagc cccctgcgcg ctgcacatgg ggcgcctgac 50

 ggaagcggcg gcagcgggca gcggctctcg ggctgcaggc tgggcagggt 100

 cccctcccac gctcctgccg ctgtctccca cgtcccccag gtgcgcggcc 150

 accatggcgt ccagcgacga ggacggcacc aacggcggcg cctcggaggc 200

 cggcgaggac cgggaggctc ccggcaagcg gaggcgcctg gggttcttgg 250

 ccaccgcctg gctcaccttc tacgacatcg ccatgaccgc ggggtggttg 300

 gttctagcta ttgccatggt acgtttttat atggaaaaag gaacacacag 350

 aggtttatat aaaagtattc agaagacact taaatttttc cagacatttg 400

 ccttgcttga gatagttcac tgtttaattg gaattgtacc tacttctgtg 450

 attgtgactg gggtccaagt gagttcaaga atctttatgg tgtggctcat 500

 tactcacagt ataaaaccaa tccagaatga agagagtgtg gtgctttttc 550

 tggtcgcgtg gactgtgaca gagatcactc gctattcctt ctacacattc 600

 agccttcttg accacttgcc atacttcatt aaatgggcca gatataattt 650

 ttttatcatc ttatatcctg ttggagttgc tggtgaactt cttacaatat 700

 acgctgcctt gccgcatgtg aagaaaacag gaatgttttc aataagactt 750

 cctaacaaat acaatgtctc ttttgactac tattattttc ttcttataac 800

 catggcatca tatatacctt tgtttccaca actctatttt catatgttac 850

 gtcaaagaag aaaggtgctt catggagagg tgattgtaga aaaggatgat 900

 taaatgatct ctgcaaacaa ggtgcttttt ccagaataac caagattacc 950

 tgagtccaag ttttaataac aagaataaac aactttgtga aatatcaaaa 1000

 aaaaaaaaaa aaaaaaaaaa aaaaaa 1026

<210> 6195
<211> 288
<212> PRT
<213> Homo sapien

<400> 6195
 Met Gly Arg Leu Thr Glu Ala Ala Ala Ala Gly Ser Gly Ser Arg
   1               5                  10                  15

 Ala Ala Gly Trp Ala Gly Ser Pro Pro Thr Leu Leu Pro Leu Ser
                  20                  25                  30

 Pro Thr Ser Pro Arg Cys Ala Ala Thr Met Ala Ser Ser Asp Glu
                  35                  40                  45

 Asp Gly Thr Asn Gly Gly Ala Ser Glu Ala Gly Glu Asp Arg Glu
                  50                  55                  60

 Ala Pro Gly Lys Arg Arg Arg Leu Gly Phe Leu Ala Thr Ala Trp
                  65                  70                  75

 Leu Thr Phe Tyr Asp Ile Ala Met Thr Ala Gly Trp Leu Val Leu
                  80                  85                  90

 Ala Ile Ala Met Val Arg Phe Tyr Met Glu Lys Gly Thr His Arg
                  95                 100                 105

 Gly Leu Tyr Lys Ser Ile Gln Lys Thr Leu Lys Phe Phe Gln Thr
                 110                 115                 120

 Phe Ala Leu Leu Glu Ile Val His Cys Leu Ile Gly Ile Val Pro
                 125                 130                 135

 Thr Ser Val Ile Val Thr Gly Val Gln Val Ser Ser Arg Ile Phe
                 140                 145                 150

 Met Val Trp Leu Ile Thr His Ser Ile Lys Pro Ile Gln Asn Glu
                 155                 160                 165

 Glu Ser Val Val Leu Phe Leu Val Ala Trp Thr Val Thr Glu Ile
                 170                 175                 180

 Thr Arg Tyr Ser Phe Tyr Thr Phe Ser Leu Leu Asp His Leu Pro
                 185                 190                 195

 Tyr Phe Ile Lys Trp Ala Arg Tyr Asn Phe Phe Ile Ile Leu Tyr
                 200                 205                 210

 Pro Val Gly Val Ala Gly Glu Leu Leu Thr Ile Tyr Ala Ala Leu
                 215                 220                 225

 Pro His Val Lys Lys Thr Gly Met Phe Ser Ile Arg Leu Pro Asn
                 230                 235                 240

 Lys Tyr Asn Val Ser Phe Asp Tyr Tyr Tyr Phe Leu Leu Ile Thr
                 245                 250                 255

 Met Ala Ser Tyr Ile Pro Leu Phe Pro Gln Leu Tyr Phe His Met
                 260                 265                 270

 Leu Arg Gln Arg Arg Lys Val Leu His Gly Glu Val Ile Val Glu
                 275                 280                 285

 Lys Asp Asp


<210> 6196
<211> 2362
<212> DNA
<213> Homo sapien

<400> 6196
 ggaattccaa aaaaaaaaaa tacgactaca cctgctccgg agcccgcggc 50

 ggtacctgca gcggaggagc tctgtcttcc ccttcatctc acgcgagccc 100

 ggcgtcccgc cgcgtgcgcc ccggcgcagc ccgccagtcc gcccggagcc 150

 cgcccagtcg ccgcgctgca cgcccggggt gaaccctctg ccctcgctgg 200

 gacagagggc cccgcagccg tcatgctttc cgccatctac acagtcctgg 250

 cgggactgct gttcctgccg ctcctggtga acctctgctg cccatacttc 300

 ttccaggaca taggctactt cttgaaggtg gccgccgtgg gccggagggt 350

 gcgcagctac gggcagcggc ggccggcgcg caccatcctg cgggcgttcc 400

 tggagaaagc gcgccagacg ccacacaagc cttttctgct cttccgcgac 450

 gagactctca cctacgcgca ggtggaccgg cgcagcaatc aagtggcccg 500

 ggcgctgcac gaccacctcg gcctgcgcca gggagactgc gtggcgctcc 550

 ttatgggtaa cgagccggcc tacgtgtggc tgtggctggg gctggtgaag 600

 ctgggctgtg ccatggcgtg cctcaattac aacatccgcg cgaagtccct 650

 gctgcactgc ttccagtgct gcggggcgaa ggtgctgctg gtgtcgccag 700

 aactacaagc agctgtcgaa gagatactgc caagccttaa aaaagatgat 750

 gtgtccatct attatgtgag cagaacttct aacacagatg ggattgactc 800

 tttcctggac aaagtggatg aagtatcaac tgaacctatc ccagagtcat 850

 ggaggtctga agtcactttt tccactcctg ccttatacat ttatacttct 900

 ggaaccacag gtcttccaaa agcagccatg atcactcatc agcgcatatg 950

 gtatggaact ggcctcactt ttgtaagcgg attgaaggca gatgatgtca 1000

 tctatatcac tctgcccttt taccacagtg ctgcactact gattggcatt 1050

 cacggatgta ttgtggctgg tgctactctt gccttgcgga ctaaattttc 1100

 agccagccag ttttgggatg actgcagaaa atacaacgtc actgtcattc 1150

 agtatatcgg tgaactgctt cggtatttat gcaactcacc acagaaacca 1200

 aatgaccgtg atcataaagt gagactggca ctgggaaatg gcttacgagg 1250

 agatgtgtgg agacaatttg tcaagagatt tggggacata tgcatctatg 1300

 agttctatgc tgccactgaa ggcaatattg gatttatgaa ttatgcgaga 1350

 aaagttggtg ctgttggaag agtaaactac ctacagaaaa aaatcataac 1400

 ttatgacctg attaaatatg atgtggagaa agatgaacct gtccgagatg 1450

 aaaatggata ttgcgtcaga gttcccaaag gtgaagttgg acttctggtt 1500

 tgcaaaatca cacaacttac accatttaat ggctatgctg gagcaaaggc 1550

 tcagacagag aagaaaaaac tgagagatgt ctttaagaaa ggagacctct 1600

 atttcaacag tggagatctc ttaatggttg accatgaaaa tttcatctat 1650

 ttccacgaca gagttggaga tacattccgg tggaaagggg aaaatgtggc 1700

 caccactgaa gttgctgata cagttggact ggttgatttt gtccaagaag 1750

 taaatgttta tggagtgcat gtgccagatc atgagggtcg cattggcatg 1800

 gcctccatca aaatgaaaga aaaccatgaa tttgatggaa agaaactctt 1850

 tcagcacatt gctgattacc tacctagtta tgcaaggccc cggtttctaa 1900

 gaatacagga caccattgag atcactggaa cttttaaaca ccgcaaaatg 1950

 accctggtgg aggagggctt taaccctgct gtcatcaaag atgccttgta 2000

 tttcttggat gacacagcaa aaatgtatgt gcctatgact gaggacatct 2050

 ataatgccat aagtgctaaa accctgaaac tctgaatatt cccaggagga 2100

 taactcaaca tttccagaaa gaaactgaat ggacagccac ttgatataat 2150

 ccaactttaa tttgattgaa gattgtgagg aaattttgta ggaaatttgc 2200

 atacccgtaa agggagactt ttttaaataa cagttgagtc tttgcaagta 2250

 aaaagattta gagattatta tttttcagtg tgcacctact gtttgtattt 2300

 gcaaactgag cttgttggag ggaaggcatt attttttaaa atacttagta 2350

 aattaaatga ac 2362

<210> 6197
<211> 620
<212> PRT
<213> Homo sapien

<400> 6197
 Met Leu Ser Ala Ile Tyr Thr Val Leu Ala Gly Leu Leu Phe Leu
   1               5                  10                  15

 Pro Leu Leu Val Asn Leu Cys Cys Pro Tyr Phe Phe Gln Asp Ile
                  20                  25                  30

 Gly Tyr Phe Leu Lys Val Ala Ala Val Gly Arg Arg Val Arg Ser
                  35                  40                  45

 Tyr Gly Gln Arg Arg Pro Ala Arg Thr Ile Leu Arg Ala Phe Leu
                  50                  55                  60

 Glu Lys Ala Arg Gln Thr Pro His Lys Pro Phe Leu Leu Phe Arg
                  65                  70                  75

 Asp Glu Thr Leu Thr Tyr Ala Gln Val Asp Arg Arg Ser Asn Gln
                  80                  85                  90

 Val Ala Arg Ala Leu His Asp His Leu Gly Leu Arg Gln Gly Asp
                  95                 100                 105

 Cys Val Ala Leu Leu Met Gly Asn Glu Pro Ala Tyr Val Trp Leu
                 110                 115                 120

 Trp Leu Gly Leu Val Lys Leu Gly Cys Ala Met Ala Cys Leu Asn
                 125                 130                 135

 Tyr Asn Ile Arg Ala Lys Ser Leu Leu His Cys Phe Gln Cys Cys
                 140                 145                 150

 Gly Ala Lys Val Leu Leu Val Ser Pro Glu Leu Gln Ala Ala Val
                 155                 160                 165

 Glu Glu Ile Leu Pro Ser Leu Lys Lys Asp Asp Val Ser Ile Tyr
                 170                 175                 180

 Tyr Val Ser Arg Thr Ser Asn Thr Asp Gly Ile Asp Ser Phe Leu
                 185                 190                 195

 Asp Lys Val Asp Glu Val Ser Thr Glu Pro Ile Pro Glu Ser Trp
                 200                 205                 210

 Arg Ser Glu Val Thr Phe Ser Thr Pro Ala Leu Tyr Ile Tyr Thr
                 215                 220                 225

 Ser Gly Thr Thr Gly Leu Pro Lys Ala Ala Met Ile Thr His Gln
                 230                 235                 240

 Arg Ile Trp Tyr Gly Thr Gly Leu Thr Phe Val Ser Gly Leu Lys
                 245                 250                 255

 Ala Asp Asp Val Ile Tyr Ile Thr Leu Pro Phe Tyr His Ser Ala
                 260                 265                 270

 Ala Leu Leu Ile Gly Ile His Gly Cys Ile Val Ala Gly Ala Thr
                 275                 280                 285

 Leu Ala Leu Arg Thr Lys Phe Ser Ala Ser Gln Phe Trp Asp Asp
                 290                 295                 300

 Cys Arg Lys Tyr Asn Val Thr Val Ile Gln Tyr Ile Gly Glu Leu
                 305                 310                 315

 Leu Arg Tyr Leu Cys Asn Ser Pro Gln Lys Pro Asn Asp Arg Asp
                 320                 325                 330

 His Lys Val Arg Leu Ala Leu Gly Asn Gly Leu Arg Gly Asp Val
                 335                 340                 345

 Trp Arg Gln Phe Val Lys Arg Phe Gly Asp Ile Cys Ile Tyr Glu
                 350                 355                 360

 Phe Tyr Ala Ala Thr Glu Gly Asn Ile Gly Phe Met Asn Tyr Ala
                 365                 370                 375

 Arg Lys Val Gly Ala Val Gly Arg Val Asn Tyr Leu Gln Lys Lys
                 380                 385                 390

 Ile Ile Thr Tyr Asp Leu Ile Lys Tyr Asp Val Glu Lys Asp Glu
                 395                 400                 405

 Pro Val Arg Asp Glu Asn Gly Tyr Cys Val Arg Val Pro Lys Gly
                 410                 415                 420

 Glu Val Gly Leu Leu Val Cys Lys Ile Thr Gln Leu Thr Pro Phe
                 425                 430                 435

 Asn Gly Tyr Ala Gly Ala Lys Ala Gln Thr Glu Lys Lys Lys Leu
                 440                 445                 450

 Arg Asp Val Phe Lys Lys Gly Asp Leu Tyr Phe Asn Ser Gly Asp
                 455                 460                 465

 Leu Leu Met Val Asp His Glu Asn Phe Ile Tyr Phe His Asp Arg
                 470                 475                 480

 Val Gly Asp Thr Phe Arg Trp Lys Gly Glu Asn Val Ala Thr Thr
                 485                 490                 495

 Glu Val Ala Asp Thr Val Gly Leu Val Asp Phe Val Gln Glu Val
                 500                 505                 510

 Asn Val Tyr Gly Val His Val Pro Asp His Glu Gly Arg Ile Gly
                 515                 520                 525

 Met Ala Ser Ile Lys Met Lys Glu Asn His Glu Phe Asp Gly Lys
                 530                 535                 540

 Lys Leu Phe Gln His Ile Ala Asp Tyr Leu Pro Ser Tyr Ala Arg
                 545                 550                 555

 Pro Arg Phe Leu Arg Ile Gln Asp Thr Ile Glu Ile Thr Gly Thr
                 560                 565                 570

 Phe Lys His Arg Lys Met Thr Leu Val Glu Glu Gly Phe Asn Pro
                 575                 580                 585

 Ala Val Ile Lys Asp Ala Leu Tyr Phe Leu Asp Asp Thr Ala Lys
                 590                 595                 600

 Met Tyr Val Pro Met Thr Glu Asp Ile Tyr Asn Ala Ile Ser Ala
                 605                 610                 615

 Lys Thr Leu Lys Leu
                 620

<210> 6198
<211> 2220
<212> DNA
<213> Homo sapien

<400> 6198
 gtgaccggag cgagaaaccc cgcctcggca ccctgacgca gcgcaggacc 50

 caccccgtgc gtgacgccag cgtcaggcca gccccggcat gctctgcggc 100

 cgcccgcggt ccagctccga caacaggaat tttctccgag agcgggccgg 150

 gctcagttca gctgctgtcc agacccggat cggcaacagt gccgcctcca 200

 gacgttctcc tgccgctcgc ccgcccgtcc cagcgccccc agccctcccg 250

 cgagggcgcc ccgggacgga aggatccacc agtctgtcgg cgcccgccgt 300

 tctcgtggtc gccgtcgccg tcgtcgtggt ggtagtctcc gccgtcgcct 350

 gggccatggc caattacatc cacgtccctc ccggctcccc ggaggtgccc 400

 aagctgaacg tcaccgttca ggatcaggag gagcatcgct gccgggaggg 450

 ggccctgagc ctcctgcaac acctgcggcc tcactgggac ccccaggagg 500

 tgaccctgca gctcttcaca gatggaatca caaataaact tattggctgt 550

 tacgtgggaa acaccatgga ggatgtagtc ctggtgagaa tttatggcaa 600

 taagactgag ttattagtcg atcgagatga ggaagtaaag agttttcgag 650

 tgttgcaggc tcatgggtgt gcaccacaac tctactgtac cttcaataat 700

 ggactatgct atgaatttat acaaggagaa gcactggatc caaagcatgt 750

 ctgcaaccca gccattttca ggctaatagc tcgtcagctt gctaaaatcc 800

 atgctattca tgcacacaat ggctggatcc ccaaatctaa tctttggcta 850

 aagatgggaa agtatttctc tctcattccc acaggatttg cagatgaaga 900

 cattaataaa aggttcctaa gtgatatccc aagctctcag attctccagg 950

 aagagatgac ttggatgaag gagattcttt ccaacctggg ctcacctgtt 1000

 gtgctttgcc ataatgacct attgtgtaag aatataatct acaatgagaa 1050

 acaaggtgat gtacagttca ttgattatga atattctgga tacaactacc 1100

 tggcatatga tattggaaat catttcaatg aatttgcagg tgtgagtgat 1150

 gtagactata gtctgtatcc agatagagaa ctacagagtc agtggctgcg 1200

 tgcttacctt gaagcctaca aagaatttaa gggctttggg actgaagtta 1250

 ctgaaaagga ggtagaaata ctcttcattc aagtcaatca gtttgcattg 1300

 gcttctcatt tcttttgggg attgtgggct ttgattcaag ccaaatactc 1350

 cactattgag tttgatttcc ttgggtatgc aattgttcgt tttaaccagt 1400

 actttaaaat gaagcctgag gttactgcat taaaagtgcc tgagtaaaga 1450

 agagatttaa ttattctcca gtagctgagc aatgcttgtg aatcttttct 1500

 taagaaatcc caaaaagcca atattagtta aaattctgtt gtttaatttg 1550

 gttatcttgc tttataaatt atgcctctaa acaatcaaat ctatttttga 1600

 aatagactga atgatgtcaa gaaatatacc tactgctatc cgtatgtggt 1650

 ggattagaaa tgtgttaaat ctgcaaaagg tataaagatg tcagtttaat 1700

 ttctttgata atttaaccta tgttgtatgt gaattattta ttataaactt 1750

 agcacgattc tgtgactgtt tttctctgtt tcacgttcgt tgagtgtaag 1800

 caatgaaaat gtcccaaata agttttttaa gttttacttt aataagatta 1850

 atttcagtaa acattctagt tgttcagtgt aaccttttta tcttgatgca 1900

 ttgtaagtaa aatgaatcat ttactcttga aatgccagtc attgactgat 1950

 gtagataatt taggattttc atataaaaat agctgtttag gaaggtgaaa 2000

 tacattcact gtctctgttg gtggtacatc ttgttgaatt caatattaga 2050

 aagtatttct ttttggggta atataactta gaattaaatc cctgtttctc 2100

 tatgtagtct ggcagtataa atataaatat ttaccatata atcttggaat 2150

 aagtattagt taatgttacc aaaatctgta ttaaataatg ttttcaaatg 2200

 ctaaaaaaaa aaaaaaaaaa 2220

<210> 6199
<211> 452
<212> PRT
<213> Homo sapien

<400> 6199
 Met Leu Cys Gly Arg Pro Arg Ser Ser Ser Asp Asn Arg Asn Phe
   1               5                  10                  15

 Leu Arg Glu Arg Ala Gly Leu Ser Ser Ala Ala Val Gln Thr Arg
                  20                  25                  30

 Ile Gly Asn Ser Ala Ala Ser Arg Arg Ser Pro Ala Ala Arg Pro
                  35                  40                  45

 Pro Val Pro Ala Pro Pro Ala Leu Pro Arg Gly Arg Pro Gly Thr
                  50                  55                  60

 Glu Gly Ser Thr Ser Leu Ser Ala Pro Ala Val Leu Val Val Ala
                  65                  70                  75

 Val Ala Val Val Val Val Val Val Ser Ala Val Ala Trp Ala Met
                  80                  85                  90

 Ala Asn Tyr Ile His Val Pro Pro Gly Ser Pro Glu Val Pro Lys
                  95                 100                 105

 Leu Asn Val Thr Val Gln Asp Gln Glu Glu His Arg Cys Arg Glu
                 110                 115                 120

 Gly Ala Leu Ser Leu Leu Gln His Leu Arg Pro His Trp Asp Pro
                 125                 130                 135

 Gln Glu Val Thr Leu Gln Leu Phe Thr Asp Gly Ile Thr Asn Lys
                 140                 145                 150

 Leu Ile Gly Cys Tyr Val Gly Asn Thr Met Glu Asp Val Val Leu
                 155                 160                 165

 Val Arg Ile Tyr Gly Asn Lys Thr Glu Leu Leu Val Asp Arg Asp
                 170                 175                 180

 Glu Glu Val Lys Ser Phe Arg Val Leu Gln Ala His Gly Cys Ala
                 185                 190                 195

 Pro Gln Leu Tyr Cys Thr Phe Asn Asn Gly Leu Cys Tyr Glu Phe
                 200                 205                 210

 Ile Gln Gly Glu Ala Leu Asp Pro Lys His Val Cys Asn Pro Ala
                 215                 220                 225

 Ile Phe Arg Leu Ile Ala Arg Gln Leu Ala Lys Ile His Ala Ile
                 230                 235                 240

 His Ala His Asn Gly Trp Ile Pro Lys Ser Asn Leu Trp Leu Lys
                 245                 250                 255

 Met Gly Lys Tyr Phe Ser Leu Ile Pro Thr Gly Phe Ala Asp Glu
                 260                 265                 270

 Asp Ile Asn Lys Arg Phe Leu Ser Asp Ile Pro Ser Ser Gln Ile
                 275                 280                 285

 Leu Gln Glu Glu Met Thr Trp Met Lys Glu Ile Leu Ser Asn Leu
                 290                 295                 300

 Gly Ser Pro Val Val Leu Cys His Asn Asp Leu Leu Cys Lys Asn
                 305                 310                 315

 Ile Ile Tyr Asn Glu Lys Gln Gly Asp Val Gln Phe Ile Asp Tyr
                 320                 325                 330

 Glu Tyr Ser Gly Tyr Asn Tyr Leu Ala Tyr Asp Ile Gly Asn His
                 335                 340                 345

 Phe Asn Glu Phe Ala Gly Val Ser Asp Val Asp Tyr Ser Leu Tyr
                 350                 355                 360

 Pro Asp Arg Glu Leu Gln Ser Gln Trp Leu Arg Ala Tyr Leu Glu
                 365                 370                 375

 Ala Tyr Lys Glu Phe Lys Gly Phe Gly Thr Glu Val Thr Glu Lys
                 380                 385                 390

 Glu Val Glu Ile Leu Phe Ile Gln Val Asn Gln Phe Ala Leu Ala
                 395                 400                 405

 Ser His Phe Phe Trp Gly Leu Trp Ala Leu Ile Gln Ala Lys Tyr
                 410                 415                 420

 Ser Thr Ile Glu Phe Asp Phe Leu Gly Tyr Ala Ile Val Arg Phe
                 425                 430                 435

 Asn Gln Tyr Phe Lys Met Lys Pro Glu Val Thr Ala Leu Lys Val
                 440                 445                 450

 Pro Glu


<210> 6200
<211> 4695
<212> DNA
<213> Homo sapien

<400> 6200
 gggggaggga aacggagcag taacaagtat cccagagggt gctgctgagg 50

 cgacgatggc cgaggggccc gaggaagccc gaggccaccc tcccgggcag 100

 gacgatggcg ggggggacca cgagcccgtc ccttccctga gaggccctcc 150

 taccaccgcc gtcccatgcc cccgcgacga cccccaggcc gaaccccagg 200

 ccccgggccg gcccacagcc ccgggcctcg cggctgccgc cgcagccgac 250

 aaattggagc cgccgcgcga gctcaggaag cgcggggagg cggcctccgg 300

 ctccggtgca gagctgcagg agcaggcggg ctgcgaggcg cccgaagccg 350

 cggcgccacg agagagacca gctcggctga gcgcccgcga gtactcccgg 400

 caagtgcacg agtggctgtg gcagtcctac tgcggctacc tcacctggca 450

 cagcggcctg gccgccttcc cagcctactg cagcccccag ccctccccgc 500

 aaagcttccc ttcgggcggc gctgcagtcc cccaggccgc ggcgccgccg 550

 cccccgcagc tgggctatta caaccccttc tacttcctga gccccggggc 600

 cgcggggcct gacccgcgga cagctgccgg catcagcacc cctgctccag 650

 tcgcgggcct gggaccccgg gctcctcacg tgcaggcgtc ggtccgggcc 700

 actccagtga cgagggtagg atccgcagcc ccttcgcgaa gcccgagcga 750

 gaccgggcga caggcaggca gagaatatgt tattccatcc ttggcccaca 800

 gatttatggc agagatggtg gatttcttta ttctcttctt tataaaagca 850

 accattgtct taagcattat gcacctcagt gggataaagg atatctctaa 900

 gtttgctatg cattatataa tagaagaaat agatgaagac acatcaatgg 950

 aagacttgca gaaaatgatg gttgtggcac ttatatacag attattagtt 1000

 tgtttctatg agataatttg catttgggga gcaggtggag ctaccccagg 1050

 gaagttcctg ctggggcttc gagttgtgac atgtgataca tcagtgctta 1100

 ttgcaccaag tcgggtttta gtgattcctt cctcaaatgt tagcattaca 1150

 acgtccacta tccgagcttt gatcaagaat ttttcaattg cttctttttt 1200

 ccctgctttc atcacactgc tgttttttca gcataatcga acagcttatg 1250

 acattgtagc aggaaccatt gtggtaaaaa gaaatggggt cagatgatgc 1300

 cccccaaaac cctgatttcc acacactaag actaaattat gtatcaaggc 1350

 catcagtatc cctgggttac actaattgat gatttagaaa ttaaagcagt 1400

 cactccagtg tgatgcaggt gactactctg aaagtattga ttatacttga 1450

 atgccaaaga acttgtccag aagaaaaacc tgttaaattc aagtattaaa 1500

 atttttagat caaaaaggca aatgatttta taaacaatgg acaatatata 1550

 ctttcttaag atctaaggta ctttcttaag atctaagaat ttgctgaaag 1600

 cattttcagc tttgaaatct ccaaatgaaa ctttaaaatt tattttggtt 1650

 tatcccaaaa taatggaaaa tgtccagttg tgttttgtaa acacctatgt 1700

 aactcatctt ttagtttaca cttcctgggg aaattgtctt tggtgtttag 1750

 aggagggaat gagaacacaa attggataat ccactgtctc ccatcccagg 1800

 aggtggtgag ttggctacaa gagaaaggga caagtgaggc aggcctagca 1850

 gttcccttac ctgaagtttt caaatccata ctgcagttcc ctctcgtaat 1900

 gatgtaactt tacaactatt cttaatgctt gaacatgtat ttaggggcaa 1950

 gtttctcatg atgatgaaaa agtatcaagt catattgcta tgttaattgg 2000

 tttttttttt taaaaggtaa gttagtgatt actgttaatg gtgggggagt 2050

 aagttttcac tgtaaattga acttataatt tatgtgcaag tgttttcagt 2100

 gccctgaatc aaactataaa tgtggggaga aatcacctcc atcaaacagt 2150

 tgcatattta ctgtaaaagt attcccagta tgtgtgcagc atgaagaaag 2200

 tattagtgct tctcagtgtt ctcagtgtaa attctattta tatacagcat 2250

 attcacatac tactttcctt atattttata tagttctatg actgttgaaa 2300

 catcaaggag ttaaaaaaat cttaatattt catgattaac tctaagtact 2350

 attaatagct tgcgaaatat tagcaatttt cccattatgg actatctctc 2400

 taaagcaaga gagactagca ttcccagaca tcattctagg gtctttaagc 2450

 tcattttggg tctgctaaag tttgggggga aatgttacgc aaagtgatac 2500

 tgtgtatgtt gccattttgc tttattcttc tgttgaagca aaattgtggg 2550

 gttttattat gtgtgtgtgc ttttcctaga tgtcccagtt agctgtgctg 2600

 agatatacct gtactattta tggtttaagt tttgattctt aggtattttc 2650

 tccagctctg acattgtttt ccaaagacac actaaactgc attgcacagt 2700

 tcaaaatttg attacttaag ggatcaatct aggtggtgtt cttggtctta 2750

 aatttaacag caaacacagc acatatctat tatcactata ttaattttca 2800

 aaggtttttc tgtgacgttt aaaactgtga caacagatat tcacatttga 2850

 ttatagaaac ttaatgtcta ttaataattt tagtacaaaa tttcataaac 2900

 cgtgtttttc aaaataagtt tatgtcaaat ccagcttccc agaaacacta 2950

 ataattaagt acatcaatgt actaaataaa tcattcagtt gcacccatgg 3000

 ggaagattgt gttactgccc ttcacagtga aaaaaagaaa aatctttcat 3050

 ttttaaaatt aggagatgtt acgtaacttg gcactttagt agtgtataca 3100

 ctagcattag tttatacacc acttttgccg ctggggattc aagttgaaat 3150

 gtccctcaat catataggtc tggaatacat ctttcattca taatttctgc 3200

 tcagataatt gaatagtttg ccatcgagat tattttcatt tatactataa 3250

 aacaaaagca aactagtcca gtttaatttt ttgtacttag aatattgcac 3300

 attttctata tatgagttat tcagattagt atctatgtag gttcagtcag 3350

 atccaaccat ggattcgagg tattatactg tataacccta caaaatacat 3400

 agaagtatta tttgccttca taatagaacc caagagtctg tttcaattta 3450

 tgaattcagt atttgcaccg agattttgat tcccaaagtt tggaaaaaaa 3500

 tgacaaaaca acgagggaag aaggaaccag accttagtgc cacatatttt 3550

 tctcttgggg ttgtaaggta gtctcctgct ttccagaaca ctttattata 3600

 tttcacttat agacctgatt ttctgtgtca aagtataatt ctcatgctga 3650

 agctgtagcc taaaaagcca aaagaaagtt gtcttcattg tacaaacata 3700

 ttcatcactt taacaataag ggaacaaaat ttagtattca agctgagtga 3750

 gaatactggt tcaatggaca tgtccctaag ataaaccaga attggcagtt 3800

 aatttaggcg tctagaaaat ctcagttccc accagtaaaa ttatcctgag 3850

 tagctaatgc accttgagaa aaatctggca tactgaataa gtaacattaa 3900

 cttgggagcc aagagctggg taagccttac ctttagacta ctctgtgact 3950

 acagaaataa agccagcact tttggaacta ataagccttc acttgtcagt 4000

 atcataaaga gtattgccca actgaacttt gctcccactg gtttaatagt 4050

 tacttatttc tgcctaagca ctcaccttcc gattttaccc aagtatatat 4100

 ataggataga aaaaaatgca ttatatttga gagctcactt cgcccgaatt 4150

 acaaaatgag tgtttttaga ttcaagtgac ggtaaaagga tttgttccct 4200

 tcagtgactt gagtgtttta gttatgcata agtatttcta gcaaaggaag 4250

 ggtagaaagg aattgaaaat taatttacac tagttgctac ttgggaataa 4300

 agggcttttt gaggggggta tggatattaa atgttttcgt tatatactta 4350

 tccctattaa aacaggcagt tgtttctttg aatatgccta aataacagta 4400

 ttcttaaaat ctgacagaca agtaacatgt caattacttg atattccttg 4450

 tctccagtac cacaggccac tcttgacatc ccatgtttgc ctggataaag 4500

 ttcctcattt caaacagtat acatacttct ttgcagttca ttatagtaag 4550

 gcttaacctg taaacagtat ctgatggccc acctataaat aaaattcagc 4600

 attctatttt taataatttg tatgccacca atttgtatta tttgtctcaa 4650

 taaatactta gtcatcgatg caaaaaaaaa aaaaaaaaaa aaaaa 4695

<210> 6201
<211> 413
<212> PRT
<213> Homo sapien

<400> 6201
 Met Ala Glu Gly Pro Glu Glu Ala Arg Gly His Pro Pro Gly Gln
   1               5                  10                  15

 Asp Asp Gly Gly Gly Asp His Glu Pro Val Pro Ser Leu Arg Gly
                  20                  25                  30

 Pro Pro Thr Thr Ala Val Pro Cys Pro Arg Asp Asp Pro Gln Ala
                  35                  40                  45

 Glu Pro Gln Ala Pro Gly Arg Pro Thr Ala Pro Gly Leu Ala Ala
                  50                  55                  60

 Ala Ala Ala Ala Asp Lys Leu Glu Pro Pro Arg Glu Leu Arg Lys
                  65                  70                  75

 Arg Gly Glu Ala Ala Ser Gly Ser Gly Ala Glu Leu Gln Glu Gln
                  80                  85                  90

 Ala Gly Cys Glu Ala Pro Glu Ala Ala Ala Pro Arg Glu Arg Pro
                  95                 100                 105

 Ala Arg Leu Ser Ala Arg Glu Tyr Ser Arg Gln Val His Glu Trp
                 110                 115                 120

 Leu Trp Gln Ser Tyr Cys Gly Tyr Leu Thr Trp His Ser Gly Leu
                 125                 130                 135

 Ala Ala Phe Pro Ala Tyr Cys Ser Pro Gln Pro Ser Pro Gln Ser
                 140                 145                 150

 Phe Pro Ser Gly Gly Ala Ala Val Pro Gln Ala Ala Ala Pro Pro
                 155                 160                 165

 Pro Pro Gln Leu Gly Tyr Tyr Asn Pro Phe Tyr Phe Leu Ser Pro
                 170                 175                 180

 Gly Ala Ala Gly Pro Asp Pro Arg Thr Ala Ala Gly Ile Ser Thr
                 185                 190                 195

 Pro Ala Pro Val Ala Gly Leu Gly Pro Arg Ala Pro His Val Gln
                 200                 205                 210

 Ala Ser Val Arg Ala Thr Pro Val Thr Arg Val Gly Ser Ala Ala
                 215                 220                 225

 Pro Ser Arg Ser Pro Ser Glu Thr Gly Arg Gln Ala Gly Arg Glu
                 230                 235                 240

 Tyr Val Ile Pro Ser Leu Ala His Arg Phe Met Ala Glu Met Val
                 245                 250                 255

 Asp Phe Phe Ile Leu Phe Phe Ile Lys Ala Thr Ile Val Leu Ser
                 260                 265                 270

 Ile Met His Leu Ser Gly Ile Lys Asp Ile Ser Lys Phe Ala Met
                 275                 280                 285

 His Tyr Ile Ile Glu Glu Ile Asp Glu Asp Thr Ser Met Glu Asp
                 290                 295                 300

 Leu Gln Lys Met Met Val Val Ala Leu Ile Tyr Arg Leu Leu Val
                 305                 310                 315

 Cys Phe Tyr Glu Ile Ile Cys Ile Trp Gly Ala Gly Gly Ala Thr
                 320                 325                 330

 Pro Gly Lys Phe Leu Leu Gly Leu Arg Val Val Thr Cys Asp Thr
                 335                 340                 345

 Ser Val Leu Ile Ala Pro Ser Arg Val Leu Val Ile Pro Ser Ser
                 350                 355                 360

 Asn Val Ser Ile Thr Thr Ser Thr Ile Arg Ala Leu Ile Lys Asn
                 365                 370                 375

 Phe Ser Ile Ala Ser Phe Phe Pro Ala Phe Ile Thr Leu Leu Phe
                 380                 385                 390

 Phe Gln His Asn Arg Thr Ala Tyr Asp Ile Val Ala Gly Thr Ile
                 395                 400                 405

 Val Val Lys Arg Asn Gly Val Arg
                 410

<210> 6202
<211> 3082
<212> DNA
<213> Homo sapien

<400> 6202
 catttgcctt ctcgttttgg cctaaggata gagtaatgat aaaccgctta 50

 gacaacatct gtgaagcagt gttgaaaggc aaatggccag taaataggcg 100

 ccagatgttt gatttccaag gcctcatccc aggttacaca cccaccacag 150

 tggacagccc cttgcagaag aggagctttg ctgagctctc catggtcggc 200

 caagccagca ttagtgggag tgaggacatc actacgtctc ctcagttgtc 250

 aaaggaagat gccctcaacc tctctgtccc tcgccagcgg aggaggagga 300

 ggagaaaaat cgaaattgag gccgaaagag ctgccaagag gcgaaatctc 350

 atggagatgg ttgcccagct tcgagagtct caggtggtct cagaaaatgg 400

 acaagaaaaa gttgtagatt tatcaaaggc ctcaagagag gcaacaagct 450

 ctacctcaaa tttttcatct ctttcttcaa agtttatctt gcctaatgtc 500

 tcaacaccag tgtctgatgc ctttaagact caaatggaac tgctccaagc 550

 aggcctttcg cgcacaccca caaggcatct ccttaatggc tccctagtgg 600

 atggagagcc tcccatgaag aggaggcggg gaaggaggaa aaatgtggag 650

 ggacttgatc tgcttttcat gagccacaaa cggacgtcat tgagtgcaga 700

 ggatgctgag gtgaccaaag cttttgaaga agatatagag accccaccaa 750

 caagaaacat tccttctccc ggacagctgg acccagacac acggatccct 800

 gttatcaatc ttgaagatgg gactaggctg gtgggggaag atgctcctaa 850

 aaataaggat ttagttgaat ggctgaagct gcaccctact tacactgttg 900

 atatgccaag ttatgtacca aagaatgcag atgtgctgtt ttcctcattt 950

 cagaaaccga aacagaaacg acatagatgt cgaaacccta ataaattgga 1000

 tataaacact ttgacaggag aagaaagggt gcctgttgtc aataaacgaa 1050

 atgggaagaa gatgggtgga gctatggcgc ctccaatgaa ggatctaccc 1100

 aggtggctgg aagaaaatcc tgaatttgca gttgctccag actggactga 1150

 tatagttaag cagtctggtt ttgttcctga gtcgatgttt gaccgccttc 1200

 tcactgggcc tgtagtgcgg ggagagggag cgagcagaag aggaagaagg 1250

 cccaaaagtg agatcgccag agcagccgcg gccgccgctg ctgtggcctc 1300

 cacgtcaggg atcaaccctt tgctggtgaa cagcctgttt gctggaatgg 1350

 acctgacgag ccttcagaat ctccagaatc tccagtcgct ccagctggca 1400

 ggcctcatgg gcttccctcc aggactggca acagctgcca ccgccggagg 1450

 cgatgcgaag aaccctgctg ctgtgctgcc cctgatgctg ccaggaatgg 1500

 cgggcctgcc caacgtgttt ggcttgggcg ggctgttgaa taaccctctg 1550

 tcagctgcta ctggaaacac cactactgct tctagtcaag gagaaccgga 1600

 agacagcact tcaaaaggag aggagaaagg aaatgagaat gaagacgaga 1650

 acaaagactc tgagaaaagc acagatgctg tttcggctgc tgactctgcg 1700

 aatggatctg ttggtgctgc tactgccccg gctggattgc cctcaaaccc 1750

 gctagccttc aaccctttcc tcctgtccac aatggccccg ggcctcttct 1800

 acccatccat gtttctacct ccaggactgg ggggattgac gctgcctggg 1850

 ttcccagcat tggcaggact tcagaatgcc gtgggctcca gcgaagaaaa 1900

 ggctgctgac aaggctgagg gaggaccctt taaagatgga gagacccttg 1950

 aaggcagcga tgccgaggag agcctggata agactgcaga gtcctccctc 2000

 ttagaagacg aaatagcaca gggtgaagag ctagactcac ttgatggggg 2050

 ggatgaaata gaaaacaatg aaaatgatga ataaccagta ccagttccag 2100

 ttcaagtgtt taaaactttt gacaagtggt agtcctactg tttacactca 2150

 cagttaatgt tcatacctag ttttataagc tgttctgtaa catagtgtag 2200

 caaaaaaaaa agttcaagtc atgttataca ggtgtgtcaa aaggtatctt 2250

 ggtcattaag tattgtgcag tgcattattt attatcccta ggagagatga 2300

 aatttgagag gtgatcatgt ctttttaagg aaacttacat aatgctctgc 2350

 tttttttttt tctcttggta ccattggtat tataataaag agcaatttgt 2400

 aactgagtgg cactaatgga agaaagtgct gctcaaagga agtatgaagt 2450

 tatatattta attttttaat tttaattttt aatttttttg ctgtgaaggt 2500

 caagctgaaa tttaccatac atatcatact tgctcatttg tttccctttt 2550

 tgactgtatg ggggttccca cactcgtgca tacacacaca tccatacact 2600

 ctgacaatct ccacgctagt gtgaacgcct ctgtcccgag gcgcagcaat 2650

 aataaggcag ctgttgaatg tgaagggtcc ctttggaaaa ttaacctact 2700

 gggagggttc ttgccagaca gaactacagt tccattgtct cgtggtcttg 2750

 taatgcactg gtaaaaacaa aataaataga tgaataaata aagagtgaga 2800

 gaagagagaa tcaggtacct tttttaaatt aaaggacttt gttactttag 2850

 ccacaaagct aaaacagcat tacctcagct ctaaactagc cttgaagttt 2900

 acagacatga ctttgtaaat gtattgtttt tctttgttgt gatgtccttt 2950

 tatttttttc tctgaaaact gctatcatgt aagataaaat gtaaattgct 3000

 gccaactgta gtaatgatgc ttttaataaa agtgacccat gatatgcaga 3050

 gatgtaaaaa aaaaaaaaaa aaaaaaaaaa aa 3082

<210> 6203
<211> 682
<212> PRT
<213> Homo sapien

<400> 6203
 Met Ile Asn Arg Leu Asp Asn Ile Cys Glu Ala Val Leu Lys Gly
   1               5                  10                  15

 Lys Trp Pro Val Asn Arg Arg Gln Met Phe Asp Phe Gln Gly Leu
                  20                  25                  30

 Ile Pro Gly Tyr Thr Pro Thr Thr Val Asp Ser Pro Leu Gln Lys
                  35                  40                  45

 Arg Ser Phe Ala Glu Leu Ser Met Val Gly Gln Ala Ser Ile Ser
                  50                  55                  60

 Gly Ser Glu Asp Ile Thr Thr Ser Pro Gln Leu Ser Lys Glu Asp
                  65                  70                  75

 Ala Leu Asn Leu Ser Val Pro Arg Gln Arg Arg Arg Arg Arg Arg
                  80                  85                  90

 Lys Ile Glu Ile Glu Ala Glu Arg Ala Ala Lys Arg Arg Asn Leu
                  95                 100                 105

 Met Glu Met Val Ala Gln Leu Arg Glu Ser Gln Val Val Ser Glu
                 110                 115                 120

 Asn Gly Gln Glu Lys Val Val Asp Leu Ser Lys Ala Ser Arg Glu
                 125                 130                 135

 Ala Thr Ser Ser Thr Ser Asn Phe Ser Ser Leu Ser Ser Lys Phe
                 140                 145                 150

 Ile Leu Pro Asn Val Ser Thr Pro Val Ser Asp Ala Phe Lys Thr
                 155                 160                 165

 Gln Met Glu Leu Leu Gln Ala Gly Leu Ser Arg Thr Pro Thr Arg
                 170                 175                 180

 His Leu Leu Asn Gly Ser Leu Val Asp Gly Glu Pro Pro Met Lys
                 185                 190                 195

 Arg Arg Arg Gly Arg Arg Lys Asn Val Glu Gly Leu Asp Leu Leu
                 200                 205                 210

 Phe Met Ser His Lys Arg Thr Ser Leu Ser Ala Glu Asp Ala Glu
                 215                 220                 225

 Val Thr Lys Ala Phe Glu Glu Asp Ile Glu Thr Pro Pro Thr Arg
                 230                 235                 240

 Asn Ile Pro Ser Pro Gly Gln Leu Asp Pro Asp Thr Arg Ile Pro
                 245                 250                 255

 Val Ile Asn Leu Glu Asp Gly Thr Arg Leu Val Gly Glu Asp Ala
                 260                 265                 270

 Pro Lys Asn Lys Asp Leu Val Glu Trp Leu Lys Leu His Pro Thr
                 275                 280                 285

 Tyr Thr Val Asp Met Pro Ser Tyr Val Pro Lys Asn Ala Asp Val
                 290                 295                 300

 Leu Phe Ser Ser Phe Gln Lys Pro Lys Gln Lys Arg His Arg Cys
                 305                 310                 315

 Arg Asn Pro Asn Lys Leu Asp Ile Asn Thr Leu Thr Gly Glu Glu
                 320                 325                 330

 Arg Val Pro Val Val Asn Lys Arg Asn Gly Lys Lys Met Gly Gly
                 335                 340                 345

 Ala Met Ala Pro Pro Met Lys Asp Leu Pro Arg Trp Leu Glu Glu
                 350                 355                 360

 Asn Pro Glu Phe Ala Val Ala Pro Asp Trp Thr Asp Ile Val Lys
                 365                 370                 375

 Gln Ser Gly Phe Val Pro Glu Ser Met Phe Asp Arg Leu Leu Thr
                 380                 385                 390

 Gly Pro Val Val Arg Gly Glu Gly Ala Ser Arg Arg Gly Arg Arg
                 395                 400                 405

 Pro Lys Ser Glu Ile Ala Arg Ala Ala Ala Ala Ala Ala Ala Val
                 410                 415                 420

 Ala Ser Thr Ser Gly Ile Asn Pro Leu Leu Val Asn Ser Leu Phe
                 425                 430                 435

 Ala Gly Met Asp Leu Thr Ser Leu Gln Asn Leu Gln Asn Leu Gln
                 440                 445                 450

 Ser Leu Gln Leu Ala Gly Leu Met Gly Phe Pro Pro Gly Leu Ala
                 455                 460                 465

 Thr Ala Ala Thr Ala Gly Gly Asp Ala Lys Asn Pro Ala Ala Val
                 470                 475                 480

 Leu Pro Leu Met Leu Pro Gly Met Ala Gly Leu Pro Asn Val Phe
                 485                 490                 495

 Gly Leu Gly Gly Leu Leu Asn Asn Pro Leu Ser Ala Ala Thr Gly
                 500                 505                 510

 Asn Thr Thr Thr Ala Ser Ser Gln Gly Glu Pro Glu Asp Ser Thr
                 515                 520                 525

 Ser Lys Gly Glu Glu Lys Gly Asn Glu Asn Glu Asp Glu Asn Lys
                 530                 535                 540

 Asp Ser Glu Lys Ser Thr Asp Ala Val Ser Ala Ala Asp Ser Ala
                 545                 550                 555

 Asn Gly Ser Val Gly Ala Ala Thr Ala Pro Ala Gly Leu Pro Ser
                 560                 565                 570

 Asn Pro Leu Ala Phe Asn Pro Phe Leu Leu Ser Thr Met Ala Pro
                 575                 580                 585

 Gly Leu Phe Tyr Pro Ser Met Phe Leu Pro Pro Gly Leu Gly Gly
                 590                 595                 600

 Leu Thr Leu Pro Gly Phe Pro Ala Leu Ala Gly Leu Gln Asn Ala
                 605                 610                 615

 Val Gly Ser Ser Glu Glu Lys Ala Ala Asp Lys Ala Glu Gly Gly
                 620                 625                 630

 Pro Phe Lys Asp Gly Glu Thr Leu Glu Gly Ser Asp Ala Glu Glu
                 635                 640                 645

 Ser Leu Asp Lys Thr Ala Glu Ser Ser Leu Leu Glu Asp Glu Ile
                 650                 655                 660

 Ala Gln Gly Glu Glu Leu Asp Ser Leu Asp Gly Gly Asp Glu Ile
                 665                 670                 675

 Glu Asn Asn Glu Asn Asp Glu
                 680

<210> 6204
<211> 1294
<212> DNA
<213> Homo sapien

<400> 6204
 tggtggaatt tctgaaggga agtgatgaaa ttatatttat ttcagtgggc 50

 acttttccat tttaccactg taccattatt tggttcctgg agttatacac 100

 taattttcag tatattactg ttaaattacc aacacaaggc aatttatttg 150

 aaagattccg tttatcctgc cattgctttg aaaagcagca ggaaacgaaa 200

 tcctttgact tgtatcagct tctgcagagc atctttgttt tcctttgtcc 250

 tttgtttcct accttttgaa tcagattccg ttttagtcag gaagacttct 300

 tgggaccatt cttagtaacc tgaaatttct tttttaattg catgaagtgg 350

 attgatcatg agcaaatgat gtgcttattt ctccctcact gttgaatatc 400

 tttgaacttg ctgttttcaa tatgggcagc acaaaggtga gagatacata 450

 ttaatagtag tatgtattac tcttatacat tagataccta tatttaaatg 500

 aaaggcccaa tttgtaaaca tatacattca tattctctct tgccccaagt 550

 tttaggaaca tgttaggata taggagactt aatttataat aatgagagca 600

 tttttttatt ttactaaagc catttttata gtcaactatc ttttcttatt 650

 tgtgtgatta gaacttagaa aaatatttac tagttgaagt tattatcagt 700

 ttttaattta gttcttaaac tcatttcact tctaataatt tctgttataa 750

 attgccagca ttttaatgaa aatctaatga tgtaataggc attttcttta 800

 tttgaaccta cctcttttat tttctgaacc aaagagaaag atggactggt 850

 gtttgtgaaa catttttaaa aatgtagttt catttatatt agttatgttt 900

 gataaatgtc tcagtatttt tataatatga taagcctggg attctacttt 950

 tagggttatt tgtacttttg agtaatatat aaagtgacaa tattaaggta 1000

 catgatcagc tctttctatt tttactcgta aaaattatgg aaatgaataa 1050

 ttttgctaac aactttgaaa tttcaaactt ctggaaaata tgaaaatatt 1100

 cattgttcat tatgaattta aattgtaagg tatgaatgtg atttgtctgt 1150

 acatcttgta tcttttccaa aaaatgattc tgtatctttt ggaaaaaagc 1200

 cgagagttga agatagtata tttctggtag tactgaatat ttacttacag 1250

 tttctatcaa aaatatatat ttgtttctaa aaaaaaaaaa aaaa 1294

<210> 6205
<211> 96
<212> PRT
<213> Homo sapien

<400> 6205
 Met Lys Leu Tyr Leu Phe Gln Trp Ala Leu Phe His Phe Thr Thr
   1               5                  10                  15

 Val Pro Leu Phe Gly Ser Trp Ser Tyr Thr Leu Ile Phe Ser Ile
                  20                  25                  30

 Leu Leu Leu Asn Tyr Gln His Lys Ala Ile Tyr Leu Lys Asp Ser
                  35                  40                  45

 Val Tyr Pro Ala Ile Ala Leu Lys Ser Ser Arg Lys Arg Asn Pro
                  50                  55                  60

 Leu Thr Cys Ile Ser Phe Cys Arg Ala Ser Leu Phe Ser Phe Val
                  65                  70                  75

 Leu Cys Phe Leu Pro Phe Glu Ser Asp Ser Val Leu Val Arg Lys
                  80                  85                  90

 Thr Ser Trp Asp His Ser
                  95

<210> 6206
<211> 4447
<212> DNA
<213> Homo sapien

<400> 6206
 atgcggcggc gctcgcggat gctgctctgc ttcgccttcc tgtgggtgct 50

 gggcatcgcc tactacatgt actcgggggg cggctctgcg ctggccgggg 100

 gcgcgggcgg cggcgccggc aggaaggagg actggaatga aattgacccc 150

 attaaaaaga aagaccttca tcacagcaat ggagaagaga aagcacaaag 200

 catggagacc ctccctccag ggaaagtacg gtggccagac tttaaccagg 250

 aagcttatgt tggagggacg atggtccgct ccgggcagga cccttacgcc 300

 cgcaacaagt tcaaccaggt ggagagtgat aagcttcgaa tggacagagc 350

 catccctgac acccggcatg accagtgtca gcggaagcag tggcgggtgg 400

 atctgccggc caccagcgtg gtgatcacgt ttcacaatga agccaggtcg 450

 gccctactca ggaccgtggt cagcgtgctt aagaaaagcc cgccccatct 500

 cataaaagaa atcatcttgg tggatgacta cagcaatgat cctgaggacg 550

 gggctctctt ggggaaaatt gagaaagtgc gagttcttag aaatgatcga 600

 cgagaaggcc tcatgcgctc acgggttcgg ggggccgatg ctgcccaagc 650

 caaggtcctg accttcctgg acagtcactg cgagtgtaat gagcactggc 700

 tggagcccct cctggaaagg gtggcggagg acaggactcg ggttgtgtca 750

 cccatcatcg atgtcattaa tatggacaac tttcagtatg tgggggcatc 800

 tgctgacttg aagggcggtt ttgattggaa cttggtattc aagtgggatt 850

 acatgacgcc tgagcagaga aggtcccggc aggggaaccc agtcgcccct 900

 ataaaaaccc ccatgattgc tggtgggctg tttgtgatgg ataagttcta 950

 ttttgaagaa ctggggaagt acgacatgat gatggatgtg tggggaggag 1000

 agaacctaga gatctcgttc cgcgtgtggc agtgtggtgg cagcctggag 1050

 atcatcccgt gcagccgtgt gggacacgtg ttccggaagc agcaccccta 1100

 cacgttcccg ggtggcagtg gcactgtctt tgcccgaaac acccgccggg 1150

 cagcagaggt ctggatggat gaatacaaaa atttctatta tgcagcagtg 1200

 ccttctgcta gaaacgttcc ttatggaaat attcagagca gattggagct 1250

 taggaagaaa ctcagctgca agcctttcaa atggtacctt gaaaatgtct 1300

 atccagagtt aagggttcca gaccatcagg atatagcttt tggggccttg 1350

 cagcagggaa ctaactgcct cgacactttg ggacactttg ctgatggtgt 1400

 ggttggagtt tatgaatgtc acaatgctgg gggaaaccag gaatgggcct 1450

 tgacgaagga gaagtcggtg aagcacatgg atttgtgcct tactgtggtg 1500

 gaccgggcac cgggctctct tataaagctg cagggctgcc gagaaaatga 1550

 cagcagacag aaatgggaac agatcgaggg caactccaag ctgaggcacg 1600

 tgggcagcaa cctgtgcctg gacagtcgca cggccaagag cgggggccta 1650

 agcgtggagg tgtgtggccc ggccctttcg cagcagtgga agttcacgct 1700

 caacctgcag cagtaggagg gtccgggagg ccctgccgtc ctgtctcctg 1750

 caccattggg tggagtctgg tgatcgcatt attgattatg tttcttaaac 1800

 tttctgcgaa actaatatac ctcagtattc catcatggtc tgaaagtcaa 1850

 acttcggcaa ggcacggacg actgtgcaga cacatcagcg gcaagaagcg 1900

 agaactgccc tccccctcct ctcggtgcag ccagccgggc ccccttcccc 1950

 aggccggagc gcccctcttc cttccagctt tcacttctgc cggtccgcaa 2000

 ctgagtgaca cccagcgaca accgactggg gagtggtaga agcaactgaa 2050

 cggatgcgtg cgagctgagg acagggcggg aggaggggca cacatgcccc 2100

 aggggagcga ggagaactct tgaaatctcc attttcaatc ccttcgaaat 2150

 cacgtatggt ttccacaaag ccgagtcgtg tcacgtggca ggtttacgtc 2200

 aatagtccct ctctctgctc ctccattcgc aagtgtcttc ctgggccaga 2250

 ctcccctccc cctcatgtac ttgctatatt gaggatgaag ttttctatgg 2300

 tgggacacta aatataaagc tatatagaga aagaatgtac ggtcagttcc 2350

 ctatggtttc tgtagatcat cgtcatcttg tatattcccc acaaagccgt 2400

 tcgcagcttc cgggagaagg ggccagagcc cggtatgggg caagttctct 2450

 aacagaggga ggaggtggcc tttgtgtccc ctggaggccc ccggatccag 2500

 ccagttggtg ctactgctgt ggccagctgg ggggcttcct ccagaccacc 2550

 ggcctcggcc ccggcatccc tgttgggcgt cagcctgaga gtccctactg 2600

 tgcgtcagaa tccaccttgc gtgctgtgcg tatctgtgaa cctgggagac 2650

 ggttacttat tttgacagat atcactttgg gtctttttac attaaatttc 2700

 ttttctctaa ggaatataag acatacccca tagctctgtg tgagccagca 2750

 ataccgctgc cccctggcga cagggcagac caatgatgcc aggcagctgt 2800

 cacacgctag tattggcttc attgtgatct gagccctgca cgctgggcct 2850

 tcagaattaa tggccagcag tgtcagggat gagcccgtca gccagggcac 2900

 aggcctggct cacagtcctg cacacctgct ggcctggggg agctccagcc 2950

 aggcagcgag tcctgccccg cccgcagctc cctcccacac cccgcctggc 3000

 caagatgact gcttcagggg gctttgggga aagaattagg aagggtcaga 3050

 accaaacaat acctgctcat ttacactgag gattcagggc gggagacagg 3100

 agccttgggg tcctgttaaa ccacagacag ttatgaactg aaagtcataa 3150

 cggggagagg tgcctggctt ctacctgggt gctcaggaat gttcctcctc 3200

 acccctgcca ctctgtggtc ggtgccctgc ttcctcctcc actcctggcc 3250

 gccttctcca gcgccgcaca cacagatgct cagtctcaga gaggctggca 3300

 cggcctggca gtctgagaaa atcgtcagtt agccactgca ggccctcggt 3350

 gggacagcgg cggccttgga ttaggagcca cctgggagtg tgccggtgcc 3400

 atgctcctcc ctgtgtcttg tatgaaaggg ccactgtgtg tcttcctccc 3450

 cggcgggagc ccacatgttg cactgtagga cagcggcccg aagtggaagc 3500

 ctggctggag gctgccctat aggtctctct ccgcctcccc tgccatgcaa 3550

 ccagatgtgt gtgaatgggc cacgtgcccc cacgctggat actccgccac 3600

 gcttctgtct ttcacggtgg gcgctcgggg ggagctgaga aaacccctta 3650

 gtactgtgcg agctgtggag tgcaggccag agcagggtgt gcgtagcccc 3700

 cagcacccag gttcttctgt cagaccctgt gacctgcgag ctgctactac 3750

 tgtaaggagg gaaatggatg aatctggctc gttttaaaat cacgttttct 3800

 gacgaatcct ttgccccttc acctttaccc cgcccgcacc cctaggccct 3850

 ctcagccttc ctatcatccc acgtgtctac ccagaccctt gtgcggccca 3900

 tgccctgggg gcggcgtcct gtccctgagc tgggaggcgg ctttggatgg 3950

 tccgggcgtc aagagcaggg gtgggccggg gaggggtcct ttgcggtgag 4000

 ctatgtttac attgacacag tgtgccaaag tgacttactg cggttgcgtt 4050

 agtttctgtc atcaggacac tatctcaccc tcccactcct gtttttaaaa 4100

 ctcagaattc tttcctaaga gcccttcgaa gcaaagcgtg ccgaagttag 4150

 ttgtcttctc tgtgctggtc ctttcttatg tcctcataaa agctcagatg 4200

 atggtatctg tgagtatgtt ttgcaaattc aaaatatagt ttggtaattt 4250

 tttttgccag ttgattttta aaaagaactg ctgtacagag ctagtacttt 4300

 gtccatttta tgaatggaaa ccatccttga aaattgttta acttaaataa 4350

 agagaagata ctttctagat accgctcttt gctggccaga gtctgtcctg 4400

 gtgtgtgaag gctgggtggg gtgggtgtgg ggactgggat tggggtc 4447

<210> 6207
<211> 571
<212> PRT
<213> Homo sapien

<400> 6207
 Met Arg Arg Arg Ser Arg Met Leu Leu Cys Phe Ala Phe Leu Trp
   1               5                  10                  15

 Val Leu Gly Ile Ala Tyr Tyr Met Tyr Ser Gly Gly Gly Ser Ala
                  20                  25                  30

 Leu Ala Gly Gly Ala Gly Gly Gly Ala Gly Arg Lys Glu Asp Trp
                  35                  40                  45

 Asn Glu Ile Asp Pro Ile Lys Lys Lys Asp Leu His His Ser Asn
                  50                  55                  60

 Gly Glu Glu Lys Ala Gln Ser Met Glu Thr Leu Pro Pro Gly Lys
                  65                  70                  75

 Val Arg Trp Pro Asp Phe Asn Gln Glu Ala Tyr Val Gly Gly Thr
                  80                  85                  90

 Met Val Arg Ser Gly Gln Asp Pro Tyr Ala Arg Asn Lys Phe Asn
                  95                 100                 105

 Gln Val Glu Ser Asp Lys Leu Arg Met Asp Arg Ala Ile Pro Asp
                 110                 115                 120

 Thr Arg His Asp Gln Cys Gln Arg Lys Gln Trp Arg Val Asp Leu
                 125                 130                 135

 Pro Ala Thr Ser Val Val Ile Thr Phe His Asn Glu Ala Arg Ser
                 140                 145                 150

 Ala Leu Leu Arg Thr Val Val Ser Val Leu Lys Lys Ser Pro Pro
                 155                 160                 165

 His Leu Ile Lys Glu Ile Ile Leu Val Asp Asp Tyr Ser Asn Asp
                 170                 175                 180

 Pro Glu Asp Gly Ala Leu Leu Gly Lys Ile Glu Lys Val Arg Val
                 185                 190                 195

 Leu Arg Asn Asp Arg Arg Glu Gly Leu Met Arg Ser Arg Val Arg
                 200                 205                 210

 Gly Ala Asp Ala Ala Gln Ala Lys Val Leu Thr Phe Leu Asp Ser
                 215                 220                 225

 His Cys Glu Cys Asn Glu His Trp Leu Glu Pro Leu Leu Glu Arg
                 230                 235                 240

 Val Ala Glu Asp Arg Thr Arg Val Val Ser Pro Ile Ile Asp Val
                 245                 250                 255

 Ile Asn Met Asp Asn Phe Gln Tyr Val Gly Ala Ser Ala Asp Leu
                 260                 265                 270

 Lys Gly Gly Phe Asp Trp Asn Leu Val Phe Lys Trp Asp Tyr Met
                 275                 280                 285

 Thr Pro Glu Gln Arg Arg Ser Arg Gln Gly Asn Pro Val Ala Pro
                 290                 295                 300

 Ile Lys Thr Pro Met Ile Ala Gly Gly Leu Phe Val Met Asp Lys
                 305                 310                 315

 Phe Tyr Phe Glu Glu Leu Gly Lys Tyr Asp Met Met Met Asp Val
                 320                 325                 330

 Trp Gly Gly Glu Asn Leu Glu Ile Ser Phe Arg Val Trp Gln Cys
                 335                 340                 345

 Gly Gly Ser Leu Glu Ile Ile Pro Cys Ser Arg Val Gly His Val
                 350                 355                 360

 Phe Arg Lys Gln His Pro Tyr Thr Phe Pro Gly Gly Ser Gly Thr
                 365                 370                 375

 Val Phe Ala Arg Asn Thr Arg Arg Ala Ala Glu Val Trp Met Asp
                 380                 385                 390

 Glu Tyr Lys Asn Phe Tyr Tyr Ala Ala Val Pro Ser Ala Arg Asn
                 395                 400                 405

 Val Pro Tyr Gly Asn Ile Gln Ser Arg Leu Glu Leu Arg Lys Lys
                 410                 415                 420

 Leu Ser Cys Lys Pro Phe Lys Trp Tyr Leu Glu Asn Val Tyr Pro
                 425                 430                 435

 Glu Leu Arg Val Pro Asp His Gln Asp Ile Ala Phe Gly Ala Leu
                 440                 445                 450

 Gln Gln Gly Thr Asn Cys Leu Asp Thr Leu Gly His Phe Ala Asp
                 455                 460                 465

 Gly Val Val Gly Val Tyr Glu Cys His Asn Ala Gly Gly Asn Gln
                 470                 475                 480

 Glu Trp Ala Leu Thr Lys Glu Lys Ser Val Lys His Met Asp Leu
                 485                 490                 495

 Cys Leu Thr Val Val Asp Arg Ala Pro Gly Ser Leu Ile Lys Leu
                 500                 505                 510

 Gln Gly Cys Arg Glu Asn Asp Ser Arg Gln Lys Trp Glu Gln Ile
                 515                 520                 525

 Glu Gly Asn Ser Lys Leu Arg His Val Gly Ser Asn Leu Cys Leu
                 530                 535                 540

 Asp Ser Arg Thr Ala Lys Ser Gly Gly Leu Ser Val Glu Val Cys
                 545                 550                 555

 Gly Pro Ala Leu Ser Gln Gln Trp Lys Phe Thr Leu Asn Leu Gln
                 560                 565                 570

 Gln


<210> 6208
<211> 2815
<212> DNA
<213> Homo sapien

<400> 6208
 gaattcggca cgagctcttc tcccctgatt caagactcct ctgctttgga 50

 ctgaagcact gcaggagttt gtgaccaaga acttcaagag tcaagacaga 100

 aggaagccaa gggagcagtg caatggattt ctcagtaaag gtagacatag 150

 agaaggaggt gacctgcccc atctgcctgg agctcctgac agaacctctg 200

 agcctagatt gtggccacag cttctgccaa gcctgcatca ctgcaaagat 250

 caaggagtca gtgatcatct caagagggga aagcagctgt cctgtgtgtc 300

 agaccagatt ccagcctggg aacctccgac ctaatcggca tctggccaac 350

 atagttgaga gagtcaaaga ggtcaagatg agcccacagg aggggcagaa 400

 gagagatgtc tgtgagcacc atggaaaaaa actccagatc ttctgtaagg 450

 aggatggaaa agtcatttgc tgggtttgtg aactgtctca ggaacaccaa 500

 ggtcaccaaa cattccgcat aaacgaggtg gtcaaggaat gtcaggaaaa 550

 gctgcaggta gccctgcaga ggctgataaa ggaggatcaa gaggctgaga 600

 agctggaaga tgacatcaga caagagagaa ccgcctggaa gatcgagaga 650

 cagaagattc tgaaagggtt caatgaaatg agagtcatct tggacaatga 700

 ggagcagaga gagctgcaaa agctggagga aggtgaggtg aatgtgctgg 750

 acaacctggc agcagctaca gaccagctgg tccagcagag gcaggatgcc 800

 agcacgctca tctcagatct ccagcggagg ttgacgggat cgtcagtaga 850

 gatgctgcag gatgtgattg acgtcatgaa aaggagtgaa agctggacat 900

 tgaagaagcc aaaatctgtt tccaagaaac taaagagtgt attccgagta 950

 ccagatctga gtgggatgct gcaagttctt aaagagctga cagatgtcca 1000

 gtactactgg gtggacgtga tgctgaatcc aggcagtgcc acttcgaatg 1050

 ttgctatttc tgtggatcag agacaagtga aaactgtacg cacctgcaca 1100

 tttaagaatt caaatccatg tgatttttct gcttttggtg tcttcggctg 1150

 ccaatatttc tcttcgggga aatattactg ggaagtagat gtgtctggaa 1200

 agattgcctg gatcctgggc gtacacagta aaataagtag tctgaataaa 1250

 aggaagagct ctgggtttgc ttttgatcca agtgtaaatt attcaaaagt 1300

 ttactccaga tatagacctc aatatggcta ctgggttata ggattacaga 1350

 atacatgtga atataatgct tttgaggact cctcctcttc tgatcccaag 1400

 gttttgactc tctttatggc tgtgctccct gtcgtattgg ggttttccta 1450

 gactatgagg caggcattgt ctcatttttc aatgtcacaa accacggagc 1500

 actcatctac aagttctctg gatgtcgctt ttctcgacct gcttatccgt 1550

 atttcaatcc ttggaactgc ctagtcccca tgactgtgtg cccaccgagc 1600

 tcctgagtgt tctcattcct ttacccactt ctgcatagta gcccttgtgc 1650

 tgagactcag attctgcacc tgagttcatc tctactgaga ccatctcttc 1700

 ctttctttcc ccttctttta cttagaatgt ctttgtattc atttgctagg 1750

 gcttccatag caaagcatca tagattgctg atttaaactg taattgtatt 1800

 gccgtactgt gggctggaaa tcccaaatct agattccagc agagttggtt 1850

 ctttctgagg tctgcaagga agggctctgt tccatgcctc tctccttggc 1900

 ttgtagaagg catcttgtcc ctatgactct tcacattgtc tttatgtaca 1950

 tctctgtgcc caagttttcc ctttttatta agacaccagt catactggct 2000

 cagggcccac cgctaatgcc ttaatgaaat cattttaaca ttatattctc 2050

 tacaaagacc ttatttccaa ataagataat atttggaggt attgggaata 2100

 aaatttgagg aaggcacgat ttcactcata acaatcttac cctttcttgc 2150

 aagagatgct tgtacattat tttcctaata ccttggtttc actagtagta 2200

 aacattatta ttttttttat atttgcaaag gaaacatatc taatccttcc 2250

 tatagaaaga acagtattgc tgtaattcct tttcttttct tcctcatttc 2300

 ctctgcccct taaaagattg aagaaagaga aacttgtcaa ctcatatcca 2350

 cgttatctag caaaagtcat aagaatctat cactaagtaa tgtatccttc 2400

 agaatgtgtt ggtttaccag tgacacccca tattcatcac aaaattaaag 2450

 caagaagtcc atagtaattt atttgctaat agtggatttt taatgctcag 2500

 agtttctgag gtcaaatttt atcttttcac ttacaagctc tatgatctta 2550

 aataatttac ttaatgtatt ttggtgtatt ttcctcaaat taatattggt 2600

 gttcaagact atatctaatt cctctgatca ctttgagaaa caaactttta 2650

 ttaaatgtaa ggcacttttc tatgaatttt aaatataaaa ataaatattg 2700

 ttctgattat tactgaaaag atgtcagcca tttcaatgtc ttgggaaaca 2750

 attttttgtt tttgttctgt tttctttttg cttcaataaa acaatagctg 2800

 gctctaaaaa aaaaa 2815

<210> 6209
<211> 442
<212> PRT
<213> Homo sapien

<400> 6209
 Met Asp Phe Ser Val Lys Val Asp Ile Glu Lys Glu Val Thr Cys
   1               5                  10                  15

 Pro Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys
                  20                  25                  30

 Gly His Ser Phe Cys Gln Ala Cys Ile Thr Ala Lys Ile Lys Glu
                  35                  40                  45

 Ser Val Ile Ile Ser Arg Gly Glu Ser Ser Cys Pro Val Cys Gln
                  50                  55                  60

 Thr Arg Phe Gln Pro Gly Asn Leu Arg Pro Asn Arg His Leu Ala
                  65                  70                  75

 Asn Ile Val Glu Arg Val Lys Glu Val Lys Met Ser Pro Gln Glu
                  80                  85                  90

 Gly Gln Lys Arg Asp Val Cys Glu His His Gly Lys Lys Leu Gln
                  95                 100                 105

 Ile Phe Cys Lys Glu Asp Gly Lys Val Ile Cys Trp Val Cys Glu
                 110                 115                 120

 Leu Ser Gln Glu His Gln Gly His Gln Thr Phe Arg Ile Asn Glu
                 125                 130                 135

 Val Val Lys Glu Cys Gln Glu Lys Leu Gln Val Ala Leu Gln Arg
                 140                 145                 150

 Leu Ile Lys Glu Asp Gln Glu Ala Glu Lys Leu Glu Asp Asp Ile
                 155                 160                 165

 Arg Gln Glu Arg Thr Ala Trp Lys Ile Glu Arg Gln Lys Ile Leu
                 170                 175                 180

 Lys Gly Phe Asn Glu Met Arg Val Ile Leu Asp Asn Glu Glu Gln
                 185                 190                 195

 Arg Glu Leu Gln Lys Leu Glu Glu Gly Glu Val Asn Val Leu Asp
                 200                 205                 210

 Asn Leu Ala Ala Ala Thr Asp Gln Leu Val Gln Gln Arg Gln Asp
                 215                 220                 225

 Ala Ser Thr Leu Ile Ser Asp Leu Gln Arg Arg Leu Thr Gly Ser
                 230                 235                 240

 Ser Val Glu Met Leu Gln Asp Val Ile Asp Val Met Lys Arg Ser
                 245                 250                 255

 Glu Ser Trp Thr Leu Lys Lys Pro Lys Ser Val Ser Lys Lys Leu
                 260                 265                 270

 Lys Ser Val Phe Arg Val Pro Asp Leu Ser Gly Met Leu Gln Val
                 275                 280                 285

 Leu Lys Glu Leu Thr Asp Val Gln Tyr Tyr Trp Val Asp Val Met
                 290                 295                 300

 Leu Asn Pro Gly Ser Ala Thr Ser Asn Val Ala Ile Ser Val Asp
                 305                 310                 315

 Gln Arg Gln Val Lys Thr Val Arg Thr Cys Thr Phe Lys Asn Ser
                 320                 325                 330

 Asn Pro Cys Asp Phe Ser Ala Phe Gly Val Phe Gly Cys Gln Tyr
                 335                 340                 345

 Phe Ser Ser Gly Lys Tyr Tyr Trp Glu Val Asp Val Ser Gly Lys
                 350                 355                 360

 Ile Ala Trp Ile Leu Gly Val His Ser Lys Ile Ser Ser Leu Asn
                 365                 370                 375

 Lys Arg Lys Ser Ser Gly Phe Ala Phe Asp Pro Ser Val Asn Tyr
                 380                 385                 390

 Ser Lys Val Tyr Ser Arg Tyr Arg Pro Gln Tyr Gly Tyr Trp Val
                 395                 400                 405

 Ile Gly Leu Gln Asn Thr Cys Glu Tyr Asn Ala Phe Glu Asp Ser
                 410                 415                 420

 Ser Ser Ser Asp Pro Lys Val Leu Thr Leu Phe Met Ala Val Leu
                 425                 430                 435

 Pro Val Val Leu Gly Phe Ser
                 440

<210> 6210
<211> 2279
<212> DNA
<213> Homo sapien

<400> 6210
 cttggcaggg cacgtgcggg aggaagtgga gctccctgta cgcgcggccc 50

 tagtcggctc ctcaacgtgg agcgatggga ggccttgaga agaagaagta 100

 tgaacgaggc tcggccacca actacatcac ccggaacaaa gcccggaaga 150

 agctccagct gagcttggct gactttaggc ggctgtgcat tctgaagggc 200

 atttatcccc atgaacccaa acacaagaag aaggttaaca agggttctac 250

 agcagcccga acgttttacc ttatcaaaga catcaggttt ctcctccacg 300

 aacccattgt caacaagttc cgtgaataca aggtgttcgt ccggaagctc 350

 cggaaggctt atgggaagag cgagtggaac actgtagagc gtttaaagga 400

 caataagccc aactacaaac tcgaccacat catcaaggaa cggtatccca 450

 cgttcatcga tgccctgcgg gacctggacg atgccctctc catgtgcttc 500

 ctgttttcca ccttcccgcg gactggcaag tgccacgtgc agaccattca 550

 gctgtgccgc cggctcactg tggagttcat gcactacatt atcgctgccc 600

 gtgccctgcg caaggtcttc ctgtccatca aaggcattta ctaccaggcc 650

 gaggtactgg ggcagcccat cgtgtggatc actccctatg ccttctccca 700

 tgaccacccg acagacgtgg actacagggt catggccacc ttcaccgagt 750

 tctacaccac gctgctgggc tttgtcaact tccgccttta ccagttgctc 800

 aacctccact atcccccgaa gctcgagggt caggcccaag cagaggcaaa 850

 ggccggtgag ggcacctacg cgttggactc cgagagttgt atggagaaac 900

 tggcagccct cagtgccagc ctggcccgcg tggtggtgcc tgccacagag 950

 gaggaggccg aggtggatga gtttcccacc gatggggaga tgtcagcgca 1000

 ggaggaagac cgcaggaagg agctggaggc gcaggagaag cacaagaagc 1050

 tttttgaggg cctgaagttc ttcctgaacc gagaggtgcc ccgtgaggcc 1100

 ctggccttca tcatcaggag ttttggtggg gaagtgtcct gggacaaatc 1150

 tttgtgcatt ggggccacct atgacgtcac agactcccgc atcacccatc 1200

 agattgtcga ccggcctggg cagcagacct cagtcattgg caggtgctac 1250

 gtgcagcccc agtgggtgtt tgactcagtg aacgccaggc tccttctccc 1300

 cgtggcagag tacttctctg gggtgcagct gcccccacac ctttcaccct 1350

 ttgtgaccga gaaggaagga gattacgttc cacctgagaa gctgaagctg 1400

 ctggctctgc agcggggaga ggacccagga aacctgaatg agtcagaaga 1450

 ggaggaggaa gaggacgaca acaacgaagg tgatggtgat gaagagggag 1500

 aaaatgagga ggaggaggaa gatgcagagg ctggttcaga aaaggaggaa 1550

 gaggcccggc tggcagccct ggaagagcag aggatggagg ggaagaagcc 1600

 cagggtgatg gcaggcacct tgaagctgga ggataagcag cggctggccc 1650

 aggaggagga gagtgaggcc aagcgcctgg ccattatgat gatgaagaag 1700

 cgggagaagt acctgtacca gaagatcatg tttggcaaga ggcgaaaaat 1750

 ccgagaggcc aacaagctgg cggagaagcg gaaagcccac gatgaggcgg 1800

 tgaggtctga gaagaaggcc aagaaggcaa ggccggagtg agtgcctgcg 1850

 gcccctcaca gggctgaggc cagcccctag cagctggatg tggcagaggc 1900

 aggccagagg acctaagtgt gatggaccag agtcacttct cctcctcctt 1950

 tctccagcca gccctgaccc ctcatgctct ctggctgggc cagtgggcag 2000

 ccctcgcttc ccttggatgg agctgccctg ctggtgcctg gtcagagaag 2050

 aggcctctgt gcccagcctg attctctgct cccaggagcc agtgacatga 2100

 ggtgcagagg cccacccagc cccctaccta ctgcccccat tcatcctggc 2150

 tttccacagc cccctcccac acagttggac ccgtgattct cagggtgctg 2200

 tgatggggtg agggtagggg gagcatttgt tattaaatga ctggactttt 2250

 gtgccaattg caaaaaaaaa aaaaaaaaa 2279

<210> 6211
<211> 588
<212> PRT
<213> Homo sapien

<400> 6211
 Met Gly Gly Leu Glu Lys Lys Lys Tyr Glu Arg Gly Ser Ala Thr
   1               5                  10                  15

 Asn Tyr Ile Thr Arg Asn Lys Ala Arg Lys Lys Leu Gln Leu Ser
                  20                  25                  30

 Leu Ala Asp Phe Arg Arg Leu Cys Ile Leu Lys Gly Ile Tyr Pro
                  35                  40                  45

 His Glu Pro Lys His Lys Lys Lys Val Asn Lys Gly Ser Thr Ala
                  50                  55                  60

 Ala Arg Thr Phe Tyr Leu Ile Lys Asp Ile Arg Phe Leu Leu His
                  65                  70                  75

 Glu Pro Ile Val Asn Lys Phe Arg Glu Tyr Lys Val Phe Val Arg
                  80                  85                  90

 Lys Leu Arg Lys Ala Tyr Gly Lys Ser Glu Trp Asn Thr Val Glu
                  95                 100                 105

 Arg Leu Lys Asp Asn Lys Pro Asn Tyr Lys Leu Asp His Ile Ile
                 110                 115                 120

 Lys Glu Arg Tyr Pro Thr Phe Ile Asp Ala Leu Arg Asp Leu Asp
                 125                 130                 135

 Asp Ala Leu Ser Met Cys Phe Leu Phe Ser Thr Phe Pro Arg Thr
                 140                 145                 150

 Gly Lys Cys His Val Gln Thr Ile Gln Leu Cys Arg Arg Leu Thr
                 155                 160                 165

 Val Glu Phe Met His Tyr Ile Ile Ala Ala Arg Ala Leu Arg Lys
                 170                 175                 180

 Val Phe Leu Ser Ile Lys Gly Ile Tyr Tyr Gln Ala Glu Val Leu
                 185                 190                 195

 Gly Gln Pro Ile Val Trp Ile Thr Pro Tyr Ala Phe Ser His Asp
                 200                 205                 210

 His Pro Thr Asp Val Asp Tyr Arg Val Met Ala Thr Phe Thr Glu
                 215                 220                 225

 Phe Tyr Thr Thr Leu Leu Gly Phe Val Asn Phe Arg Leu Tyr Gln
                 230                 235                 240

 Leu Leu Asn Leu His Tyr Pro Pro Lys Leu Glu Gly Gln Ala Gln
                 245                 250                 255

 Ala Glu Ala Lys Ala Gly Glu Gly Thr Tyr Ala Leu Asp Ser Glu
                 260                 265                 270

 Ser Cys Met Glu Lys Leu Ala Ala Leu Ser Ala Ser Leu Ala Arg
                 275                 280                 285

 Val Val Val Pro Ala Thr Glu Glu Glu Ala Glu Val Asp Glu Phe
                 290                 295                 300

 Pro Thr Asp Gly Glu Met Ser Ala Gln Glu Glu Asp Arg Arg Lys
                 305                 310                 315

 Glu Leu Glu Ala Gln Glu Lys His Lys Lys Leu Phe Glu Gly Leu
                 320                 325                 330

 Lys Phe Phe Leu Asn Arg Glu Val Pro Arg Glu Ala Leu Ala Phe
                 335                 340                 345

 Ile Ile Arg Ser Phe Gly Gly Glu Val Ser Trp Asp Lys Ser Leu
                 350                 355                 360

 Cys Ile Gly Ala Thr Tyr Asp Val Thr Asp Ser Arg Ile Thr His
                 365                 370                 375

 Gln Ile Val Asp Arg Pro Gly Gln Gln Thr Ser Val Ile Gly Arg
                 380                 385                 390

 Cys Tyr Val Gln Pro Gln Trp Val Phe Asp Ser Val Asn Ala Arg
                 395                 400                 405

 Leu Leu Leu Pro Val Ala Glu Tyr Phe Ser Gly Val Gln Leu Pro
                 410                 415                 420

 Pro His Leu Ser Pro Phe Val Thr Glu Lys Glu Gly Asp Tyr Val
                 425                 430                 435

 Pro Pro Glu Lys Leu Lys Leu Leu Ala Leu Gln Arg Gly Glu Asp
                 440                 445                 450

 Pro Gly Asn Leu Asn Glu Ser Glu Glu Glu Glu Glu Glu Asp Asp
                 455                 460                 465

 Asn Asn Glu Gly Asp Gly Asp Glu Glu Gly Glu Asn Glu Glu Glu
                 470                 475                 480

 Glu Glu Asp Ala Glu Ala Gly Ser Glu Lys Glu Glu Glu Ala Arg
                 485                 490                 495

 Leu Ala Ala Leu Glu Glu Gln Arg Met Glu Gly Lys Lys Pro Arg
                 500                 505                 510

 Val Met Ala Gly Thr Leu Lys Leu Glu Asp Lys Gln Arg Leu Ala
                 515                 520                 525

 Gln Glu Glu Glu Ser Glu Ala Lys Arg Leu Ala Ile Met Met Met
                 530                 535                 540

 Lys Lys Arg Glu Lys Tyr Leu Tyr Gln Lys Ile Met Phe Gly Lys
                 545                 550                 555

 Arg Arg Lys Ile Arg Glu Ala Asn Lys Leu Ala Glu Lys Arg Lys
                 560                 565                 570

 Ala His Asp Glu Ala Val Arg Ser Glu Lys Lys Ala Lys Lys Ala
                 575                 580                 585

 Arg Pro Glu


<210> 6212
<211> 2756
<212> DNA
<213> Homo sapien

<400> 6212
 atgcagttag gggagcagct cttggtgagc tcagtgaacc tgcctggcgc 50

 gcacttctac ccgctggaga gtgcgcgagg cggcagcggc gggagcgctg 100

 gccacctccc cagcgcggcc ccctctcctc agaagttgga cttagacaaa 150

 gcgtccaaga agttttccgg cagtctctcc tgcgaggcgg tgagcgggga 200

 gcccgcagcc gccagcgcag gggcccccgc ggccatgctt agtgacaccg 250

 acgccgggga cgcatttgcc agcgctgcgg cagtggccaa gccggggccc 300

 ccggacggcc gcaagggctc cccctgcggg gaggaggagc tgccctccgc 350

 cgctgcagcc gccgccgccg ccgccgccgc ggctgcggcc actgcgcgct 400

 actccatgga cagcctgagc tccgagcggt actacctcca gtcccccggt 450

 cctcaggggt cggagctggc tgcgccctgc tcactcttcc cgtaccaggc 500

 ggcggctggg gcgccccacg gacctgtgta cccggctcct aacggggcgc 550

 gctaccccta cggctccatg ctgccccccg gcggcttccc cgcggctgtg 600

 tgcccacccg ggagggcgca gttcggccca ggagccggtg cgggcagtgg 650

 cgcgggcggt agcagcggcg ggggcggcgg cccgggcacc tatcagtaca 700

 gccagggggc tccgctctac gggccgtacc ctggagccgc agcggcggga 750

 tcttgcggag gactgggggg cctgggggtt ccaggttctg gcttccgtgc 800

 ccacgtctac ctgtgcaacc ggcctctgtg gctcaaattc caccgccacc 850

 aaactgagat gatcattacg aaacagggca ggcgcatgtt tcctttcttg 900

 agcttcaaca taaacggact caatcccact gcccactaca atgtgttcgt 950

 agaggtggtg ctggcggacc ccaaccactg gcgcttccag gggggcaaat 1000

 gggtgacctg tggcaaagcc gacaataaca tgcagggcaa caaaatgtat 1050

 gttcacccag agtctcctaa tactggttcc cactggatga gacaggagat 1100

 ttcattcggg aaattaaaac tcaccaataa caaaggcgca aataacaaca 1150

 acacccagat gatagtctta caatccttac acaaatacca accccgactg 1200

 catattgttg aagttacaga ggatggcgtg gaggacttga atgagccctc 1250

 aaagacccag acttttacct tctcagaaac gcaattcatt gcagtgactg 1300

 cctaccaaaa caccgatatt actcaactaa agattgatca taaccccttt 1350

 gcaaaaggct tcagagacaa ctatgattca tcccatcaga ttgtccctgg 1400

 aggtcggtac ggcgttcaat ccttcttccc ggagcccttt gtcaacactt 1450

 tacctcaagc ccgctattat aatggcgaga gaaccgtgcc acagaccaac 1500

 ggcctccttt caccccaaca gagcgaagag gtggccaacc ctccccagcg 1550

 gtggcttgtc acgcctgtcc agcaacctgg gaccaacaaa ctagacatca 1600

 gttcctatga atctgaatat acttctagca cattgctccc atatggcatt 1650

 aaatccttgc cccttcagac atcccatgcc ctggggtatt acccagaccc 1700

 aacctttcct gcaatggcag ggtggggagg tcgaggttct taccagagga 1750

 agatggcagc tggactacca tggacctcca gaacaagccc cactgtgttc 1800

 tctgaagatc agctctccaa ggagaaagtg aaagaggaaa ttggctcttc 1850

 ttggatagag acaccccctt ccatcaaatc tctagattcc aatgattcag 1900

 gagtatacac cagtgcttgt aagcgaaggc ggctgtctcc tagcaactcc 1950

 agtaatgaaa attcaccctc cataaagtgt gaggacatta atgctgaaga 2000

 gtatagtaaa gacacctcaa aaggcatggg agggtattat gctttttaca 2050

 caactcccta aagagttatt ttaacctcaa aaattagcta actttttgca 2100

 gatggacttg gtggtgtttt ttgttgtctt ctttgcctag gttgccaaaa 2150

 agatgtttgc cttccacctt gatgcatcct gttttgtgca attctctaaa 2200

 agaaggtgcc aaagcttttt gattgctgca ggtaactgaa acaaacctag 2250

 catttttaaa aaataagatt aatggaagac tttaaggtat tttaaaattc 2300

 gaagggtatc caaggttctg tatttattta ttggggagac actaaccctt 2350

 caaagaagca ggctgtgaac attgggtgcc cagtgctatc agatgagtta 2400

 aaacctttga ttctcatttc tatttgtaaa ttcttaagca aatagaagcc 2450

 gagtgttaag gtgttttgct tctgaaagag ggctgtgcct tccgtttcag 2500

 aaggagacat tttgctgtta cattctgcca ggggcaaaag atactaggcc 2550

 caggagtcaa gaaaagcttt tgtgaaagtg atagtttcac ctgactttga 2600

 ttccttaacc cccggctttt ggaacaagcc atgtttgccc tagtccagga 2650

 ttgcctcact tgagacttgc taggcctctg ctgtgtgctg gggtggccag 2700

 tgggactcag gagagagcaa gctaaggagt caccaaaaaa aaaaaaaaaa 2750

 aaaaaa 2756

<210> 6213
<211> 686
<212> PRT
<213> Homo sapien

<400> 6213
 Met Gln Leu Gly Glu Gln Leu Leu Val Ser Ser Val Asn Leu Pro
   1               5                  10                  15

 Gly Ala His Phe Tyr Pro Leu Glu Ser Ala Arg Gly Gly Ser Gly
                  20                  25                  30

 Gly Ser Ala Gly His Leu Pro Ser Ala Ala Pro Ser Pro Gln Lys
                  35                  40                  45

 Leu Asp Leu Asp Lys Ala Ser Lys Lys Phe Ser Gly Ser Leu Ser
                  50                  55                  60

 Cys Glu Ala Val Ser Gly Glu Pro Ala Ala Ala Ser Ala Gly Ala
                  65                  70                  75

 Pro Ala Ala Met Leu Ser Asp Thr Asp Ala Gly Asp Ala Phe Ala
                  80                  85                  90

 Ser Ala Ala Ala Val Ala Lys Pro Gly Pro Pro Asp Gly Arg Lys
                  95                 100                 105

 Gly Ser Pro Cys Gly Glu Glu Glu Leu Pro Ser Ala Ala Ala Ala
                 110                 115                 120

 Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Thr Ala Arg Tyr Ser
                 125                 130                 135

 Met Asp Ser Leu Ser Ser Glu Arg Tyr Tyr Leu Gln Ser Pro Gly
                 140                 145                 150

 Pro Gln Gly Ser Glu Leu Ala Ala Pro Cys Ser Leu Phe Pro Tyr
                 155                 160                 165

 Gln Ala Ala Ala Gly Ala Pro His Gly Pro Val Tyr Pro Ala Pro
                 170                 175                 180

 Asn Gly Ala Arg Tyr Pro Tyr Gly Ser Met Leu Pro Pro Gly Gly
                 185                 190                 195

 Phe Pro Ala Ala Val Cys Pro Pro Gly Arg Ala Gln Phe Gly Pro
                 200                 205                 210

 Gly Ala Gly Ala Gly Ser Gly Ala Gly Gly Ser Ser Gly Gly Gly
                 215                 220                 225

 Gly Gly Pro Gly Thr Tyr Gln Tyr Ser Gln Gly Ala Pro Leu Tyr
                 230                 235                 240

 Gly Pro Tyr Pro Gly Ala Ala Ala Ala Gly Ser Cys Gly Gly Leu
                 245                 250                 255

 Gly Gly Leu Gly Val Pro Gly Ser Gly Phe Arg Ala His Val Tyr
                 260                 265                 270

 Leu Cys Asn Arg Pro Leu Trp Leu Lys Phe His Arg His Gln Thr
                 275                 280                 285

 Glu Met Ile Ile Thr Lys Gln Gly Arg Arg Met Phe Pro Phe Leu
                 290                 295                 300

 Ser Phe Asn Ile Asn Gly Leu Asn Pro Thr Ala His Tyr Asn Val
                 305                 310                 315

 Phe Val Glu Val Val Leu Ala Asp Pro Asn His Trp Arg Phe Gln
                 320                 325                 330

 Gly Gly Lys Trp Val Thr Cys Gly Lys Ala Asp Asn Asn Met Gln
                 335                 340                 345

 Gly Asn Lys Met Tyr Val His Pro Glu Ser Pro Asn Thr Gly Ser
                 350                 355                 360

 His Trp Met Arg Gln Glu Ile Ser Phe Gly Lys Leu Lys Leu Thr
                 365                 370                 375

 Asn Asn Lys Gly Ala Asn Asn Asn Asn Thr Gln Met Ile Val Leu
                 380                 385                 390

 Gln Ser Leu His Lys Tyr Gln Pro Arg Leu His Ile Val Glu Val
                 395                 400                 405

 Thr Glu Asp Gly Val Glu Asp Leu Asn Glu Pro Ser Lys Thr Gln
                 410                 415                 420

 Thr Phe Thr Phe Ser Glu Thr Gln Phe Ile Ala Val Thr Ala Tyr
                 425                 430                 435

 Gln Asn Thr Asp Ile Thr Gln Leu Lys Ile Asp His Asn Pro Phe
                 440                 445                 450

 Ala Lys Gly Phe Arg Asp Asn Tyr Asp Ser Ser His Gln Ile Val
                 455                 460                 465

 Pro Gly Gly Arg Tyr Gly Val Gln Ser Phe Phe Pro Glu Pro Phe
                 470                 475                 480

 Val Asn Thr Leu Pro Gln Ala Arg Tyr Tyr Asn Gly Glu Arg Thr
                 485                 490                 495

 Val Pro Gln Thr Asn Gly Leu Leu Ser Pro Gln Gln Ser Glu Glu
                 500                 505                 510

 Val Ala Asn Pro Pro Gln Arg Trp Leu Val Thr Pro Val Gln Gln
                 515                 520                 525

 Pro Gly Thr Asn Lys Leu Asp Ile Ser Ser Tyr Glu Ser Glu Tyr
                 530                 535                 540

 Thr Ser Ser Thr Leu Leu Pro Tyr Gly Ile Lys Ser Leu Pro Leu
                 545                 550                 555

 Gln Thr Ser His Ala Leu Gly Tyr Tyr Pro Asp Pro Thr Phe Pro
                 560                 565                 570

 Ala Met Ala Gly Trp Gly Gly Arg Gly Ser Tyr Gln Arg Lys Met
                 575                 580                 585

 Ala Ala Gly Leu Pro Trp Thr Ser Arg Thr Ser Pro Thr Val Phe
                 590                 595                 600

 Ser Glu Asp Gln Leu Ser Lys Glu Lys Val Lys Glu Glu Ile Gly
                 605                 610                 615

 Ser Ser Trp Ile Glu Thr Pro Pro Ser Ile Lys Ser Leu Asp Ser
                 620                 625                 630

 Asn Asp Ser Gly Val Tyr Thr Ser Ala Cys Lys Arg Arg Arg Leu
                 635                 640                 645

 Ser Pro Ser Asn Ser Ser Asn Glu Asn Ser Pro Ser Ile Lys Cys
                 650                 655                 660

 Glu Asp Ile Asn Ala Glu Glu Tyr Ser Lys Asp Thr Ser Lys Gly
                 665                 670                 675

 Met Gly Gly Tyr Tyr Ala Phe Tyr Thr Thr Pro
                 680                 685

<210> 6214
<211> 3557
<212> DNA
<213> Homo sapien

<400> 6214
 gattcccggg cccacccgac ccagcggcgc gaccctggcc ctccgggacc 50

 ctccgctgac tccaccgcgc acttcccggg acccccacac acatcccagc 100

 cctccggccg atccctccct actcggtgcc gggtgccccc cgccctctcc 150

 aggcccggat ctcctccccc aggtccccgg gtcggcccca gccaggcccc 200

 cttcgaaccc cgccggcggc ccgggctggg gcgcaccatg cggctgcggc 250

 tccggcttct ggcgctgctg cttctgctgc tggcaccgcc cgcgcgcgcc 300

 ccgaagccct cggcgcagga cgtgagcctg ggcgtggact ggctgactcg 350

 ctatggttac ctgccgccac cccaccctgc ccaggcccag ctgcagagcc 400

 ctgagaagtt gcgcgatgcc atcaaagtca tgcagaggtt cgcggggctg 450

 ccggagaccg gccgcatgga cccagggaca gtggccacca tgcgtaagcc 500

 ccgctgctcc ctgcctgacg tgctgggggt ggcggggctg gtcaggcggc 550

 gtcgccggta cgctctgagc ggcagcgtgt ggaagaagcg aaccctgaca 600

 tggagggtac gttccttccc ccagagctcc cagctgagcc aggagaccgt 650

 gcgggtcctc atgagctatg ccctgatggc ctggggcatg gagtcaggcc 700

 tcacatttca tgaggtggat tccccccagg gccaggagcc cgacatcctc 750

 atcgactttg cccgcgcctt ccaccaggac agctacccct tcgacgggtt 800

 ggggggcacc ctagcccatg ccttcttccc tggggagcac cccatctccg 850

 gggacactca ctttgacgat gaggagacct ggacttttgg gtcaaaagac 900

 ggcgagggga ccgacctgtt tgccgtggct gtccatgagt ttggccacgc 950

 cctgggcctg ggccactcct cagcccccaa ctccattatg aggcccttct 1000

 accagggtcc ggtgggcgac cctgacaagt accgcctgtc tcaggatgac 1050

 cgcgatggcc tgcagcaact ctatgggaag gcgccccaaa ccccatatga 1100

 caagcccaca aggaaacccc tggctcctcc gccccagccc ccggcctcgc 1150

 ccacacacag cccatccttc cccatccctg atcgatgtga gggcaatttt 1200

 gacgccatcg ccaacatccg aggggaaact ttcttcttca aaggcccctg 1250

 gttctggcgc ctccagccct ccggacagct ggtgtccccg cgacccgcac 1300

 ggctgcaccg cttctgggag gggctgcccg cccaggtgag ggtggtgcag 1350

 gccgcctatg ctcggcaccg agacggccga atcctcctct ttagcgggcc 1400

 ccagttctgg gtgttccagg accggcagct ggagggcggg gcgcggccgc 1450

 tcacggagct ggggctgccc ccgggagagg aggtggacgc cgtgttctcg 1500

 tggccacaga acgggaagac ctacctggtc cgcggccggc agtactggcg 1550

 ctacgacgag gcggcggcgc gcccggaccc cggctaccct cgcgacctga 1600

 gcctctggga aggcgcgccc ccctcccctg acgatgtcac cgtcagcaac 1650

 gcaggtgaca cctacttctt caagggcgcc cactactggc gcttccccaa 1700

 gaacagcatc aagaccgagc cggacgcccc ccagcccatg gggcccaact 1750

 ggctggactg ccccgccccg agctctggtc cccgcgcccc caggcccccc 1800

 aaagcgaccc ccgtgtccga aacctgcgat tgtcagtgcg agctcaacca 1850

 ggccgcagga cgttggcctg ctcccatccc gctgctcctc ttgcccctgc 1900

 tggtgggggg tgtagcctcc cgctgatggg gggagccatc cagaccgaac 1950

 agcgccctcc acggccgagt cccccgccgc tggacctggt cgggggttgt 2000

 gaggcgctgc ggaggcccct tgtctgttcc cacggacggg ggctcgggcg 2050

 cggactaagc aggggggatc tcccgcgcag gggcggcggc ggcggggacc 2100

 ggtcgcctgg cgctgggctc agtctcctca gggtctgaga ccccggcgct 2150

 gccaccggaa cccgccttca ggggcgcacg cgcgctggga ccatgcgtcg 2200

 gtcgtcgccc ccgtcgttcc ctcccggctg ccgccagggg gcggtcggac 2250

 cccgcctccc gagcccgggg aggggcgggg aggacaaggg gcgggcccgc 2300

 ggcctcaccc ggagggacgg cagccccggt cgcgcgctgg ccccgcagga 2350

 ccttcctttt ccaggaagag ccagcttttc tcggagcgca gtcctgggac 2400

 tctccgcagc cccgccccgc ctggccactg cgtctggcat tcctgggtcg 2450

 ttagaggaca ggcctgactg cgaagctgtg ccttgcccct ctcccacccg 2500

 cagtttctca ccccgttctg ctcccacaag gcccccctac agtcactgcc 2550

 acactggtgg ggacctggga cccagacccg gaaccagccc agatatcacc 2600

 cctgaggacc catgcgccac gtcctgggtg gtggaatcag tggctggagg 2650

 gacgaccctt gctctccagg ctgttaacct tttccgttgc tcccccgcca 2700

 cccacctcct cctccccagg ccacccagct tgggcacctc cctgggccca 2750

 gaactgcctt ccattcaatg gggaaccctt ctatccccaa gaaccccttc 2800

 cctgcttgca ccctggagag aacagcttga ctcccatcaa ctcaacgctg 2850

 gtggaaagac agggaccgaa ccctggctca ggcctggtca ttgcctcctc 2900

 agcactccct cctgggaggc cttagctcta gagtgagggg tgggtggaac 2950

 ctgggggcac ctcgttcacc ctgtccccac tccccacagt tttaggatct 3000

 aaatgattgc ctctggaact attcttctag actatcccac atcagaatca 3050

 ctgggaaatt taagtttgca gatcccacac tcaccctgaa tcctcactca 3100

 gggtggggtc aggaatctgc attttaacta gtcgcgggga ttgtgggggg 3150

 cagtagctgg ctgtttcgtg gcatttctgt ggctctgcag tgttcctcca 3200

 ccccaggacc aatatgttca ggccacaccg atggcctgaa ccccatgggt 3250

 agagtcactt aggggccact tcctaagttg ctgtccagcc tcagtgaccc 3300

 cctagtgctt cctggagctg aggctgtggg cggctgtccc agcaaccatg 3350

 cgaggggttg ccccagttgc tcatacaaac agatcagcat gaggacagaa 3400

 ggcaggagac tttggtcagt tacctgggaa ttctgggctg ccaggaaacg 3450

 atttgggcct ctgtcagttt cttttccatg tatgaggagg gggaaatttg 3500

 tatattagaa acttattcat cccactcagg acaataaaaa cgaatgtaca 3550

 aaaaaaa 3557

<210> 6215
<211> 562
<212> PRT
<213> Homo sapien

<400> 6215
 Met Arg Leu Arg Leu Arg Leu Leu Ala Leu Leu Leu Leu Leu Leu
   1               5                  10                  15

 Ala Pro Pro Ala Arg Ala Pro Lys Pro Ser Ala Gln Asp Val Ser
                  20                  25                  30

 Leu Gly Val Asp Trp Leu Thr Arg Tyr Gly Tyr Leu Pro Pro Pro
                  35                  40                  45

 His Pro Ala Gln Ala Gln Leu Gln Ser Pro Glu Lys Leu Arg Asp
                  50                  55                  60

 Ala Ile Lys Val Met Gln Arg Phe Ala Gly Leu Pro Glu Thr Gly
                  65                  70                  75

 Arg Met Asp Pro Gly Thr Val Ala Thr Met Arg Lys Pro Arg Cys
                  80                  85                  90

 Ser Leu Pro Asp Val Leu Gly Val Ala Gly Leu Val Arg Arg Arg
                  95                 100                 105

 Arg Arg Tyr Ala Leu Ser Gly Ser Val Trp Lys Lys Arg Thr Leu
                 110                 115                 120

 Thr Trp Arg Val Arg Ser Phe Pro Gln Ser Ser Gln Leu Ser Gln
                 125                 130                 135

 Glu Thr Val Arg Val Leu Met Ser Tyr Ala Leu Met Ala Trp Gly
                 140                 145                 150

 Met Glu Ser Gly Leu Thr Phe His Glu Val Asp Ser Pro Gln Gly
                 155                 160                 165

 Gln Glu Pro Asp Ile Leu Ile Asp Phe Ala Arg Ala Phe His Gln
                 170                 175                 180

 Asp Ser Tyr Pro Phe Asp Gly Leu Gly Gly Thr Leu Ala His Ala
                 185                 190                 195

 Phe Phe Pro Gly Glu His Pro Ile Ser Gly Asp Thr His Phe Asp
                 200                 205                 210

 Asp Glu Glu Thr Trp Thr Phe Gly Ser Lys Asp Gly Glu Gly Thr
                 215                 220                 225

 Asp Leu Phe Ala Val Ala Val His Glu Phe Gly His Ala Leu Gly
                 230                 235                 240

 Leu Gly His Ser Ser Ala Pro Asn Ser Ile Met Arg Pro Phe Tyr
                 245                 250                 255

 Gln Gly Pro Val Gly Asp Pro Asp Lys Tyr Arg Leu Ser Gln Asp
                 260                 265                 270

 Asp Arg Asp Gly Leu Gln Gln Leu Tyr Gly Lys Ala Pro Gln Thr
                 275                 280                 285

 Pro Tyr Asp Lys Pro Thr Arg Lys Pro Leu Ala Pro Pro Pro Gln
                 290                 295                 300

 Pro Pro Ala Ser Pro Thr His Ser Pro Ser Phe Pro Ile Pro Asp
                 305                 310                 315

 Arg Cys Glu Gly Asn Phe Asp Ala Ile Ala Asn Ile Arg Gly Glu
                 320                 325                 330

 Thr Phe Phe Phe Lys Gly Pro Trp Phe Trp Arg Leu Gln Pro Ser
                 335                 340                 345

 Gly Gln Leu Val Ser Pro Arg Pro Ala Arg Leu His Arg Phe Trp
                 350                 355                 360

 Glu Gly Leu Pro Ala Gln Val Arg Val Val Gln Ala Ala Tyr Ala
                 365                 370                 375

 Arg His Arg Asp Gly Arg Ile Leu Leu Phe Ser Gly Pro Gln Phe
                 380                 385                 390

 Trp Val Phe Gln Asp Arg Gln Leu Glu Gly Gly Ala Arg Pro Leu
                 395                 400                 405

 Thr Glu Leu Gly Leu Pro Pro Gly Glu Glu Val Asp Ala Val Phe
                 410                 415                 420

 Ser Trp Pro Gln Asn Gly Lys Thr Tyr Leu Val Arg Gly Arg Gln
                 425                 430                 435

 Tyr Trp Arg Tyr Asp Glu Ala Ala Ala Arg Pro Asp Pro Gly Tyr
                 440                 445                 450

 Pro Arg Asp Leu Ser Leu Trp Glu Gly Ala Pro Pro Ser Pro Asp
                 455                 460                 465

 Asp Val Thr Val Ser Asn Ala Gly Asp Thr Tyr Phe Phe Lys Gly
                 470                 475                 480

 Ala His Tyr Trp Arg Phe Pro Lys Asn Ser Ile Lys Thr Glu Pro
                 485                 490                 495

 Asp Ala Pro Gln Pro Met Gly Pro Asn Trp Leu Asp Cys Pro Ala
                 500                 505                 510

 Pro Ser Ser Gly Pro Arg Ala Pro Arg Pro Pro Lys Ala Thr Pro
                 515                 520                 525

 Val Ser Glu Thr Cys Asp Cys Gln Cys Glu Leu Asn Gln Ala Ala
                 530                 535                 540

 Gly Arg Trp Pro Ala Pro Ile Pro Leu Leu Leu Leu Pro Leu Leu
                 545                 550                 555

 Val Gly Gly Val Ala Ser Arg
                 560

<210> 6216
<211> 583
<212> DNA
<213> Homo sapien

<400> 6216
 gccagctgcc ggtctttcgg gggctccgta actttctatc cgtccgcgtc 50

 agcgccttgc caccctcatc tccaatatgc ctggtccgac ccccagtggc 100

 actaacgtgg gatcctcagg gcgctctccc agcaaagcag tggccgcccg 150

 ggcggcggga tccactgtcc ggcagaggaa aaatgccagc tgtgggacaa 200

 ggagtgcagg ccgcacaacc tcggcaggca ccggggggat gtggcgattc 250

 tacacagaag attcacctgg gctcaaagtt ggccctgttc cagtattggt 300

 tatgagtctt ctgttcatcg cttctgtatt tatgttgcac atttggggca 350

 agtacactcg ttcgtagatt cagttacatc catctgtcat ctgaagaagg 400

 aggaaaaaac ccaacatttc ttggaccaaa agtatagtga ctatctgttc 450

 atgagagaaa ttttctgtaa gcttgctgtt ttacagggga tttatcaata 500

 attgattttg aggaatcagt ttttttctat ggctaataaa ctttttaatt 550

 cacttatact gaaaaaaaaa aaaaaaaaaa aaa 583

<210> 6217
<211> 96
<212> PRT
<213> Homo sapien

<400> 6217
 Met Pro Gly Pro Thr Pro Ser Gly Thr Asn Val Gly Ser Ser Gly
   1               5                  10                  15

 Arg Ser Pro Ser Lys Ala Val Ala Ala Arg Ala Ala Gly Ser Thr
                  20                  25                  30

 Val Arg Gln Arg Lys Asn Ala Ser Cys Gly Thr Arg Ser Ala Gly
                  35                  40                  45

 Arg Thr Thr Ser Ala Gly Thr Gly Gly Met Trp Arg Phe Tyr Thr
                  50                  55                  60

 Glu Asp Ser Pro Gly Leu Lys Val Gly Pro Val Pro Val Leu Val
                  65                  70                  75

 Met Ser Leu Leu Phe Ile Ala Ser Val Phe Met Leu His Ile Trp
                  80                  85                  90

 Gly Lys Tyr Thr Arg Ser
                  95

<210> 6218
<211> 1421
<212> DNA
<213> Homo sapien

<400> 6218
 acttactgcg ggacggcctt ggagagtact cgggttcgtg aacttcccgg 50

 aggcgcaatg agctgcatta acctgcccac tgtgctgccc ggctccccca 100

 gcaagacccg ggggcagatc caggtgattc tcgggccgat gttctcagga 150

 aaaagcacag agttgatgag acgcgtccgt cgcttccaga ttgctcagta 200

 caagtgcctg gtgatcaagt atgccaaaga cactcgctac agcagcagct 250

 tctgcacaca tgaccggaac accatggagg cgctgcccgc ctgcctgctc 300

 cgagacgtgg cccaggaggc cctgggcgtg gctgtcatag gcatcgacga 350

 ggggcagttt ttccctgaca tcatggagtt ctgcgaggcc atggccaacg 400

 ccgggaagac cgtaattgtg gctgcactgg atgggacctt ccagaggaag 450

 ccatttgggg ccatcctgaa cctggtgccg ctggccgaga gcgtggtgaa 500

 gctgacggcg gtgtgcatgg agtgcttccg ggaagccgcc tataccaaga 550

 ggctcggcac agagaaggag gtcgaggtga ttgggggagc agacaagtac 600

 cactccgtgt gtcggctctg ctacttcaag aaggcctcag gccagcctgc 650

 cgggccggac aacaaagaga actgcccagt gccaggaaag ccaggggaag 700

 ccgtggctgc caggaagctc tttgccccac agcagattct gcaatgcagc 750

 cctgccaact gagggacctg caagggccgc ccgctccctt cctgccactg 800

 ccgcctactg gacgctgccc tgcatgctgc ccagccactc caggaggaag 850

 tcgggaggcg tggagggtga ccacaccttg gccttctggg aactctcctt 900

 tgtgtggctg ccccacctgc cgcatgctcc ctcctctcct acccactggt 950

 ctgcttaaag cttccctctc agctgctggg acgatcgccc aggctggagc 1000

 tggccccgct tggtggcctg ggatctggca cactccctct ccttggggtg 1050

 agggacagag ccccacgctg ttgacatcag cctgcttctt cccctctgcg 1100

 gctttcactg ctgagtttct gttctccctg ggaagcctgt gccagcacct 1150

 ttgagccttg gcccacactg aggcttaggc ctctctgcct gggatgggct 1200

 cccaccctcc cctgaggatg gcctggattc acgccctctt gtttcctttt 1250

 gggctcaaag cccttcctac ctctggtgat ggtttccaca ggaacaacag 1300

 catctttcac caagatgggt ggcaccaacc ttgctgggac ttggatccca 1350

 ggggcttatc tcttcaagtg tggagagggc agggtccacg cctctgctgt 1400

 agcttatgaa attaactaat t 1421

<210> 6219
<211> 234
<212> PRT
<213> Homo sapien

<400> 6219
 Met Ser Cys Ile Asn Leu Pro Thr Val Leu Pro Gly Ser Pro Ser
   1               5                  10                  15

 Lys Thr Arg Gly Gln Ile Gln Val Ile Leu Gly Pro Met Phe Ser
                  20                  25                  30

 Gly Lys Ser Thr Glu Leu Met Arg Arg Val Arg Arg Phe Gln Ile
                  35                  40                  45

 Ala Gln Tyr Lys Cys Leu Val Ile Lys Tyr Ala Lys Asp Thr Arg
                  50                  55                  60

 Tyr Ser Ser Ser Phe Cys Thr His Asp Arg Asn Thr Met Glu Ala
                  65                  70                  75

 Leu Pro Ala Cys Leu Leu Arg Asp Val Ala Gln Glu Ala Leu Gly
                  80                  85                  90

 Val Ala Val Ile Gly Ile Asp Glu Gly Gln Phe Phe Pro Asp Ile
                  95                 100                 105

 Met Glu Phe Cys Glu Ala Met Ala Asn Ala Gly Lys Thr Val Ile
                 110                 115                 120

 Val Ala Ala Leu Asp Gly Thr Phe Gln Arg Lys Pro Phe Gly Ala
                 125                 130                 135

 Ile Leu Asn Leu Val Pro Leu Ala Glu Ser Val Val Lys Leu Thr
                 140                 145                 150

 Ala Val Cys Met Glu Cys Phe Arg Glu Ala Ala Tyr Thr Lys Arg
                 155                 160                 165

 Leu Gly Thr Glu Lys Glu Val Glu Val Ile Gly Gly Ala Asp Lys
                 170                 175                 180

 Tyr His Ser Val Cys Arg Leu Cys Tyr Phe Lys Lys Ala Ser Gly
                 185                 190                 195

 Gln Pro Ala Gly Pro Asp Asn Lys Glu Asn Cys Pro Val Pro Gly
                 200                 205                 210

 Lys Pro Gly Glu Ala Val Ala Ala Arg Lys Leu Phe Ala Pro Gln
                 215                 220                 225

 Gln Ile Leu Gln Cys Ser Pro Ala Asn
                 230

<210> 6220
<211> 3589
<212> DNA
<213> Homo sapien

<400> 6220
 actggcggcc atggaactca ccggtaatag aggacacatc tcttaactgg 50

 gttgctctaa gaactgatgt ctaaaccgtc tcagcatggc ctgtagagga 100

 ggagctggga atggccaccg tgcctcagct acactctctc gggttagccc 150

 tggaagtctt tacacatgta gaacccgtac ccataatata tgcatggtat 200

 ctgacttttt ctacccaaat atgggaggcg tggaaagcca catttaccag 250

 ctctctcagt gcctgattga aagagggcat aaggttataa ttgtcaccca 300

 tgcttatgga aatcgaaaag gcatccgtta cctcaccagt ggcctcaaag 350

 tctattactt gcctctgaaa gtcatgtaca accagtctac agccacgacc 400

 ctctttcaca gtctgccatt gctcaggtac atatttgttc gggagagagt 450

 cacgataatc cattcacata gttctttttc tgctatggcc catgatgctc 500

 tcttccacgc caagacaatg gggcttcaga cagtcttcac ggaccattcc 550

 ctttttggat ttgctgatgt cagctcggtg cttacaaaca agcttctaac 600

 cgtgtctctt tgtgatacaa accacatcat ttgtgtgtct tatactagta 650

 aggaaaatac tgtactaaga gcagcactga atcctgaaat agtgtccgtc 700

 attcctaatg ctgtagatcc tactgacttc actccagacc catttagaag 750

 gcatgatagt ataactattg ttgttgtcag cagacttgtt tacagaaaag 800

 ggatcgattt gcttagtggt ataatacctg aactctgtca gaaatatcca 850

 gatttaaatt tcataattgg aggagaggga ccaaagagaa tcattttgga 900

 agaagttcgg gaaagatacc agctgcatga cagggtgcgt cttttgggag 950

 ctttagaaca caaggatgtt agaaatgtct tagttcaagg acatattttt 1000

 ctgaatacct cccttactga agcattctgc atggcgatcg tggaagcagc 1050

 cagttgtggt ttacaggttg taagtaccag agttggtgga attcctgagg 1100

 tgcttccaga aaaccttatt attttatgtg agccttcagt aaaatctttg 1150

 tgtgaaggat tggaaaaggc tattttccaa ctgaagtcag ggacattgcc 1200

 agctccagaa aacatccata acatagtaaa gactttctac acctggagga 1250

 atgttgcaga aagaactgaa aaggtatatg accgggtatc agtggaagct 1300

 gtgttgccaa tggacaaacg actggacaga cttatttctc actgcggccc 1350

 agtaacaggc tacatctttg ctttgttggc agttttcaac ttcctcttcc 1400

 tcattttctt gagatggatg actccagatt ctatcattga tgttgcaata 1450

 gatgccactg ggccacgggg tgcctggact aataactatt ctcacagtaa 1500

 aagagggggt gagaataatg agatatctga aaccaggtag aaggaagcct 1550

 agattgtaag attttaaaca tttgtaatag ttctataaag actatggaaa 1600

 ataaccttgc ttttgggggg tttttgtttt tttagagtta atttagtaag 1650

 ttatgctacc tctatatcat tcaatatttt ctgttgagga aagataaaaa 1700

 tgtatgcaat tcctgagtgt agaaacttct tgcacttatt taaaatttag 1750

 gagagaacat ttaagccact caggtatgca atttttcaga ctactgaaat 1800

 ccctgtagca gagatgtttt aacattatat tttgagagct ttgggtgctg 1850

 aagggccaaa cgttttctgg gcattttttg gccagttttt aatgtaacac 1900

 cattagacac tcaccagatg tttacaagtt ttctttaggg gaactacaac 1950

 aattatatga actgttttat atcatgttca tatacattta ttaggaatct 2000

 aaatcatgtc tttgaacatt tattaggttc actcagtagg tgttacatgt 2050

 aattaacagg ttccttgagt aagatagtcc atcagttacc agcacatttt 2100

 gaacccctgc tctgtgtaga atgttgaact agatgcttcc cgccattaag 2150

 gaccaggggt gcattcactc tttgtttacc attcaaatgg cttacttcat 2200

 cataattgtg gttgatatga gatcaatatc caacatgcca aaaatgctca 2250

 tgccagttaa tgccaggaaa aaaatcaccg acacactact agtactttgt 2300

 tcctgttgta tgcattctcc taggtagagc ctccatcttc agttgtgttt 2350

 gtgaaggtat tttttgcttt ttaaatactg gggaccgata tcactgttga 2400

 tagtgcagag aaaccctcca catttttcag tgcataattg agttttctat 2450

 aaatgccttc gtgttttctg agcagaatgt acgaggtgtg ccatcccaaa 2500

 accagctgct accctgtcct tttaatgtaa gtcactcccc ttcactgtgg 2550

 cctcgctgat gtctgataag tattgtcagt gtgcaaaagg ctttacttca 2600

 gaatggttta tttatagcaa actaagttga aaattttaga aacagtcttt 2650

 gtgggtggat gttattaact gtcattgttg ttgcccagag ccatgggttt 2700

 tttaacccca aattatccac atggtgtgta ttatgaattc tttgaactct 2750

 taaggttttt gtgagaaaag gactgtgaat tcaaaacaat aaggcacttg 2800

 tgggtgcact acatagattc tgacagtgtt gtgattctgt ataggatttt 2850

 taaaaatgac aacattcaca aaatttatta ctttttaaaa aataacatgc 2900

 ctattaactg gttgcactga tataaaagaa atatatttgt gttttgtttg 2950

 tactaaaatg caaaagcaag agtgcaattt ttaaaatcta gaagttaggg 3000

 gttttgttgg agaaaaatgg actgatcttt aaactattca gtcttactgg 3050

 gatttttatg catagaaact cacatataaa catgaaataa acagtgccag 3100

 tattcatagg aaagtgagaa actgtaatat ttggccatta ttctattcaa 3150

 caggttttag aggcatgcca ccattttttc cttatatttt tgcttaattt 3200

 ttttaaattg tcatttaatt cttaaactgt catttatttg agatggaaat 3250

 aagatctaaa gttagttgcc tttgcctgta aaacatgtga tttgcaaatt 3300

 attattttcc ttttttttta acaaatggaa gtaaatttgt ttcacgtaaa 3350

 tcttaatttt caacctttct ggatacctta attgtaactg tcagtttgca 3400

 ctggtcggta tatggaaaca cattgctcta ccctgctact tagttgattt 3450

 taaagtgaat ttacagtgat gagaaatttg tgaaaaatat attgtatttc 3500

 ttttgatgtt tcaaaaggtt gcctatgaaa aactgatttg ttaaaacatg 3550

 ctacatgtcc aaaaataaag accagaatga cattttgat 3589

<210> 6221
<211> 484
<212> PRT
<213> Homo sapien

<400> 6221
 Met Ala Cys Arg Gly Gly Ala Gly Asn Gly His Arg Ala Ser Ala
   1               5                  10                  15

 Thr Leu Ser Arg Val Ser Pro Gly Ser Leu Tyr Thr Cys Arg Thr
                  20                  25                  30

 Arg Thr His Asn Ile Cys Met Val Ser Asp Phe Phe Tyr Pro Asn
                  35                  40                  45

 Met Gly Gly Val Glu Ser His Ile Tyr Gln Leu Ser Gln Cys Leu
                  50                  55                  60

 Ile Glu Arg Gly His Lys Val Ile Ile Val Thr His Ala Tyr Gly
                  65                  70                  75

 Asn Arg Lys Gly Ile Arg Tyr Leu Thr Ser Gly Leu Lys Val Tyr
                  80                  85                  90

 Tyr Leu Pro Leu Lys Val Met Tyr Asn Gln Ser Thr Ala Thr Thr
                  95                 100                 105

 Leu Phe His Ser Leu Pro Leu Leu Arg Tyr Ile Phe Val Arg Glu
                 110                 115                 120

 Arg Val Thr Ile Ile His Ser His Ser Ser Phe Ser Ala Met Ala
                 125                 130                 135

 His Asp Ala Leu Phe His Ala Lys Thr Met Gly Leu Gln Thr Val
                 140                 145                 150

 Phe Thr Asp His Ser Leu Phe Gly Phe Ala Asp Val Ser Ser Val
                 155                 160                 165

 Leu Thr Asn Lys Leu Leu Thr Val Ser Leu Cys Asp Thr Asn His
                 170                 175                 180

 Ile Ile Cys Val Ser Tyr Thr Ser Lys Glu Asn Thr Val Leu Arg
                 185                 190                 195

 Ala Ala Leu Asn Pro Glu Ile Val Ser Val Ile Pro Asn Ala Val
                 200                 205                 210

 Asp Pro Thr Asp Phe Thr Pro Asp Pro Phe Arg Arg His Asp Ser
                 215                 220                 225

 Ile Thr Ile Val Val Val Ser Arg Leu Val Tyr Arg Lys Gly Ile
                 230                 235                 240

 Asp Leu Leu Ser Gly Ile Ile Pro Glu Leu Cys Gln Lys Tyr Pro
                 245                 250                 255

 Asp Leu Asn Phe Ile Ile Gly Gly Glu Gly Pro Lys Arg Ile Ile
                 260                 265                 270

 Leu Glu Glu Val Arg Glu Arg Tyr Gln Leu His Asp Arg Val Arg
                 275                 280                 285

 Leu Leu Gly Ala Leu Glu His Lys Asp Val Arg Asn Val Leu Val
                 290                 295                 300

 Gln Gly His Ile Phe Leu Asn Thr Ser Leu Thr Glu Ala Phe Cys
                 305                 310                 315

 Met Ala Ile Val Glu Ala Ala Ser Cys Gly Leu Gln Val Val Ser
                 320                 325                 330

 Thr Arg Val Gly Gly Ile Pro Glu Val Leu Pro Glu Asn Leu Ile
                 335                 340                 345

 Ile Leu Cys Glu Pro Ser Val Lys Ser Leu Cys Glu Gly Leu Glu
                 350                 355                 360

 Lys Ala Ile Phe Gln Leu Lys Ser Gly Thr Leu Pro Ala Pro Glu
                 365                 370                 375

 Asn Ile His Asn Ile Val Lys Thr Phe Tyr Thr Trp Arg Asn Val
                 380                 385                 390

 Ala Glu Arg Thr Glu Lys Val Tyr Asp Arg Val Ser Val Glu Ala
                 395                 400                 405

 Val Leu Pro Met Asp Lys Arg Leu Asp Arg Leu Ile Ser His Cys
                 410                 415                 420

 Gly Pro Val Thr Gly Tyr Ile Phe Ala Leu Leu Ala Val Phe Asn
                 425                 430                 435

 Phe Leu Phe Leu Ile Phe Leu Arg Trp Met Thr Pro Asp Ser Ile
                 440                 445                 450

 Ile Asp Val Ala Ile Asp Ala Thr Gly Pro Arg Gly Ala Trp Thr
                 455                 460                 465

 Asn Asn Tyr Ser His Ser Lys Arg Gly Gly Glu Asn Asn Glu Ile
                 470                 475                 480

 Ser Glu Thr Arg


<210> 6222
<211> 2270
<212> DNA
<213> Homo sapien

<400> 6222
 agtgtaagca gtgtgcaaac aaggtgttac agcacatgaa ggccgtgcag 50

 gcagatcagg agcgggagag gcagcggcgg ctggaagtag aacgtgaggc 100

 agagaagaag cgtgaggcta agcagcgagc taaggaagct caggagcggg 150

 aactgcggaa gcgggagaag gcggaagaga aggagcgccg gagaaaggag 200

 tatgatgccc tcaaagcagc caagcgggag caggagaaga aacctaagaa 250

 ggaagcaaat caggccccga aatctaagtc tggctcccgt ccccgcaagc 300

 caccaccccg gaagcacact cgttcctggg ctgtgctgaa gctgctgctg 350

 ctgctgctgc tatttggtgt ggcgggaggg ctggttgctt gtcgggtgac 400

 agagctgcag cagcagcccc tctgcaccag cgtgaacacc atctatgaca 450

 atgcggtcca gggtctacgc cgccatgaga tcctccagtg ggtccttcag 500

 accgactctc agcagtgagc ttgttcccag cacctgctgc ctcccagcct 550

 tggagtttgg attcctatgg aattgggttc tgctggacac aacctctttt 600

 tagcatcaga cctacctgcc atcatcaaat ggctgcagat tggtacatga 650

 gacctcctct ttgtaggact tcttcattcc ttagtcaggg ttccctgaag 700

 gaatgaggag aaatgggagg tggcgggggg gcgtgggggg cagttacctg 750

 catgcctaaa ggagtaggct tgggggtggg gagagagaaa acatagcctt 800

 ttctagttgt tatataaagc tgtgtaaagg caaggctcgt ttctactaaa 850

 tggtcagctg tcactacatt tatacttttg tatgccacaa accctttcat 900

 tcctccctgg gaatcagggt agatcaggag gaactggggg ggactagaac 950

 accacgctca gtaaatccag tctaaactgg gaggtagggg tattcctgtt 1000

 ttctttagga cctcagagat gtaagcattt tagcagccac acaaaatctc 1050

 tggctatgaa agggacttca tgaccatcca gtccaatata acacttgcag 1100

 acagagaaac tgaggtcttc catgacttgc ctagtctccc agctagtttg 1150

 aggcaaaact ggattcccac tctggtattc tttcttccct ttacatcatt 1200

 ttccctcctt tataatgtcc tgagagacca gaactcacac cagaatcgat 1250

 tattcctcag gtgaagcata gactctttca tggtagacag atttcacgac 1300

 tcagagatag aaatctcttg ctatcatcag gtcacgggca gctcctgtgg 1350

 agtcctgccc aacttatgtg gcttccataa aatggcaaca gtccaggctc 1400

 cttgcctaat tttagagcat taactcccta attgccagta agcaaggagg 1450

 tggatctctg caaacctaca ctgtctatga cagctctagt tgtacttggt 1500

 gtgactaaat acctcaaagg caacctgctt ctgcaggttt tgaagtgtca 1550

 gcttcataag acactgaggt ttagaattgt ttgattctag accataactg 1600

 aagggcataa atggaaacag gatatgaagg gaaacaagta gcatcatgga 1650

 gctgaaaagt ggtgcatcac ccaatggcta gcacaaacaa ggatcacact 1700

 gtccattctc ttgtctgcta aattaagcat tttcttgcct cctttgcttc 1750

 atcttttcac aacagctgga tagagggatc agaaatgact gtgtcatggt 1800

 gctcattcac tgcaaactcc cagttgcaag ctccttggct cccccggagg 1850

 gagcaagaat ctcatagttc agagacacag agggcctttt agccctaatg 1900

 accttttgga tgggactgca actcatgact atcctgatat tggaagaaag 1950

 gactttgtta atcttctccc ccatagctct gctgcgtagg tctacatctt 2000

 actcagaatc actacacatt cctttagtct tcctccaagc tccagagcca 2050

 ttggtacaaa tgctttattg aaactaaata cataatacac acaatgagat 2100

 gaagacaata tagaagtccg catagtcatc ataatcccgt tccttggccg 2150

 gttgaggcag ctcagtggct gagcccagtc aagccaaccc gcagcttcac 2200

 tcacgacttc aagatttgat gctaattctt ttggatttct acagttatta 2250

 aataagtgtc tgagtggaca 2270

<210> 6223
<211> 160
<212> PRT
<213> Homo sapien

<400> 6223
 Met Lys Ala Val Gln Ala Asp Gln Glu Arg Glu Arg Gln Arg Arg
   1               5                  10                  15

 Leu Glu Val Glu Arg Glu Ala Glu Lys Lys Arg Glu Ala Lys Gln
                  20                  25                  30

 Arg Ala Lys Glu Ala Gln Glu Arg Glu Leu Arg Lys Arg Glu Lys
                  35                  40                  45

 Ala Glu Glu Lys Glu Arg Arg Arg Lys Glu Tyr Asp Ala Leu Lys
                  50                  55                  60

 Ala Ala Lys Arg Glu Gln Glu Lys Lys Pro Lys Lys Glu Ala Asn
                  65                  70                  75

 Gln Ala Pro Lys Ser Lys Ser Gly Ser Arg Pro Arg Lys Pro Pro
                  80                  85                  90

 Pro Arg Lys His Thr Arg Ser Trp Ala Val Leu Lys Leu Leu Leu
                  95                 100                 105

 Leu Leu Leu Leu Phe Gly Val Ala Gly Gly Leu Val Ala Cys Arg
                 110                 115                 120

 Val Thr Glu Leu Gln Gln Gln Pro Leu Cys Thr Ser Val Asn Thr
                 125                 130                 135

 Ile Tyr Asp Asn Ala Val Gln Gly Leu Arg Arg His Glu Ile Leu
                 140                 145                 150

 Gln Trp Val Leu Gln Thr Asp Ser Gln Gln
                 155                 160

<210> 6224
<211> 642
<212> DNA
<213> Homo sapien

<400> 6224
 gctgaagtga aaacgagacc aaggtctagc tctactgttg gtacttatga 50

 gatccagtcc tggcaacatg gagaggattg tcatctgtct gatggtcatc 100

 ttcttgggga cactggtcca caaatcaagc tcccaaggtc aagatcgcca 150

 catgattaga atgcgtcaac ttatagatat tgttgatcag ctgaaaaatt 200

 atgtgaatga cttggtccct gaatttctgc cagctccaga agatgtagag 250

 acaaactgtg agtggtcagc tttttcctgt tttcagaagg cccaactaaa 300

 gtcagcaaat acaggaaaca atgaaaggat aatcaatgta tcaattaaaa 350

 agctgaagag gaaaccacct tccacaaatg cagggagaag acagaaacac 400

 agactaacat gcccttcatg tgattcttat gagaaaaaac cacccaaaga 450

 attcctagaa agattcaaat cacttctcca aaagatgatt catcagcatc 500

 tgtcctctag aacacacgga agtgaagatt cctgaggatc taacttgcag 550

 ttggacacta tgttacatac tctaatatag tagtgaaagt catttctttg 600

 tattccaagt ggaggagccc tattaaatta tataaagaaa ta 642

<210> 6225
<211> 162
<212> PRT
<213> Homo sapien

<400> 6225
 Met Arg Ser Ser Pro Gly Asn Met Glu Arg Ile Val Ile Cys Leu
   1               5                  10                  15

 Met Val Ile Phe Leu Gly Thr Leu Val His Lys Ser Ser Ser Gln
                  20                  25                  30

 Gly Gln Asp Arg His Met Ile Arg Met Arg Gln Leu Ile Asp Ile
                  35                  40                  45

 Val Asp Gln Leu Lys Asn Tyr Val Asn Asp Leu Val Pro Glu Phe
                  50                  55                  60

 Leu Pro Ala Pro Glu Asp Val Glu Thr Asn Cys Glu Trp Ser Ala
                  65                  70                  75

 Phe Ser Cys Phe Gln Lys Ala Gln Leu Lys Ser Ala Asn Thr Gly
                  80                  85                  90

 Asn Asn Glu Arg Ile Ile Asn Val Ser Ile Lys Lys Leu Lys Arg
                  95                 100                 105

 Lys Pro Pro Ser Thr Asn Ala Gly Arg Arg Gln Lys His Arg Leu
                 110                 115                 120

 Thr Cys Pro Ser Cys Asp Ser Tyr Glu Lys Lys Pro Pro Lys Glu
                 125                 130                 135

 Phe Leu Glu Arg Phe Lys Ser Leu Leu Gln Lys Met Ile His Gln
                 140                 145                 150

 His Leu Ser Ser Arg Thr His Gly Ser Glu Asp Ser
                 155                 160

<210> 6226
<211> 1538
<212> DNA
<213> Homo sapien

<400> 6226
 atggatgggg gaaccgggcg gcgagacggc ggcaggacgg cggcaggatg 50

 tgtgaccgga atggtggtcg gcggcttcga cagtggctga tcgagcagat 100

 tgacagtagc atgtatccag gactgatttg ggagaatgag gagaagagca 150

 tgttccggat cccttggaaa cacgctggca agcaagatta taatcaggaa 200

 gtggatgcct ccatttttaa ggcctgggca gtttttaaag ggaagtttaa 250

 agaaggggac aaagctgaac cagccacttg gaagacgagg ttacgctgtg 300

 ctttgaataa gagcccagat tttgaggaag tgacggaccg gtcccaactg 350

 gacatttccg agccatacaa agtttaccga attgttcctg aggaagagca 400

 aaaatgcaaa ctaggcgtgg caactgctgg ctgcgtgaat gaagttacag 450

 agatggagtg cggtcgctct gaaatcgacg agctgatcaa ggagccttct 500

 gtggacgatt acatggggat gatcaaaagg agcccttccc cgccggaggc 550

 ctgtcggagt cagctccttc cagactggtg ggcgcagcag cccagcacag 600

 gcgtgccgct ggtgacgggg tacaccacct acgacgcgca ccattcagca 650

 ttctcccaga tggtgatcag cttctactat gggggcaagc tggtgggcca 700

 ggccaccacc acctgccccg agggctgccg cctgtccctg agccagcctg 750

 ggctgcccgg caccaagctg tatgggcccg agggcctgga gctggtgcgc 800

 ttcccgccgg ccgacgccat ccccagcgag cgacagaggc aggtgacgcg 850

 gaagctgttc gggcacctgg agcgcggggt gctgctgcac agcagccggc 900

 agggcgtgtt cgtcaagcgg ctgtgccagg gccgcgtgtt ctgcagcggc 950

 aacgccgtgg tgtgcaaagg caggcccaac aagctggagc gtgatgaggt 1000

 ggtccaggtc ttcgacacca gccagttctt ccgagagctg cagcagttct 1050

 ataacagcca gggccggctt cctgacggca gggtggtgct gtgctttggg 1100

 gaagagtttc cggatatggc ccccttgcgc tccaaactca ttctcgtgca 1150

 gattgagcag ctgtatgtcc ggcaactggc agaagaggct gggaagagct 1200

 gtggagccgg ctctgtgatg caggcccccg aggagccgcc gccagaccag 1250

 gtcttccgga tgtttccaga tatttgtgcc tcacaccaga gatcattttt 1300

 cagagaaaac caacagatca ccgtctaagt gcgtcgcttg ggcgccccac 1350

 cccgtctgcg tcctgcatcc atctccctgt tacagtggcc cgcatcatga 1400

 ttaaagaatg tggatccctc tgtctggggt gggatgcctt actttgcact 1450

 taatttaata agggcattct cggaggagta gacgtttaat acgaagtggc 1500

 gcatagccct gccgagatgt cggtgatggc ctgatgcg 1538

<210> 6227
<211> 426
<212> PRT
<213> Homo sapien

<400> 6227
 Met Cys Asp Arg Asn Gly Gly Arg Arg Leu Arg Gln Trp Leu Ile
   1               5                  10                  15

 Glu Gln Ile Asp Ser Ser Met Tyr Pro Gly Leu Ile Trp Glu Asn
                  20                  25                  30

 Glu Glu Lys Ser Met Phe Arg Ile Pro Trp Lys His Ala Gly Lys
                  35                  40                  45

 Gln Asp Tyr Asn Gln Glu Val Asp Ala Ser Ile Phe Lys Ala Trp
                  50                  55                  60

 Ala Val Phe Lys Gly Lys Phe Lys Glu Gly Asp Lys Ala Glu Pro
                  65                  70                  75

 Ala Thr Trp Lys Thr Arg Leu Arg Cys Ala Leu Asn Lys Ser Pro
                  80                  85                  90

 Asp Phe Glu Glu Val Thr Asp Arg Ser Gln Leu Asp Ile Ser Glu
                  95                 100                 105

 Pro Tyr Lys Val Tyr Arg Ile Val Pro Glu Glu Glu Gln Lys Cys
                 110                 115                 120

 Lys Leu Gly Val Ala Thr Ala Gly Cys Val Asn Glu Val Thr Glu
                 125                 130                 135

 Met Glu Cys Gly Arg Ser Glu Ile Asp Glu Leu Ile Lys Glu Pro
                 140                 145                 150

 Ser Val Asp Asp Tyr Met Gly Met Ile Lys Arg Ser Pro Ser Pro
                 155                 160                 165

 Pro Glu Ala Cys Arg Ser Gln Leu Leu Pro Asp Trp Trp Ala Gln
                 170                 175                 180

 Gln Pro Ser Thr Gly Val Pro Leu Val Thr Gly Tyr Thr Thr Tyr
                 185                 190                 195

 Asp Ala His His Ser Ala Phe Ser Gln Met Val Ile Ser Phe Tyr
                 200                 205                 210

 Tyr Gly Gly Lys Leu Val Gly Gln Ala Thr Thr Thr Cys Pro Glu
                 215                 220                 225

 Gly Cys Arg Leu Ser Leu Ser Gln Pro Gly Leu Pro Gly Thr Lys
                 230                 235                 240

 Leu Tyr Gly Pro Glu Gly Leu Glu Leu Val Arg Phe Pro Pro Ala
                 245                 250                 255

 Asp Ala Ile Pro Ser Glu Arg Gln Arg Gln Val Thr Arg Lys Leu
                 260                 265                 270

 Phe Gly His Leu Glu Arg Gly Val Leu Leu His Ser Ser Arg Gln
                 275                 280                 285

 Gly Val Phe Val Lys Arg Leu Cys Gln Gly Arg Val Phe Cys Ser
                 290                 295                 300

 Gly Asn Ala Val Val Cys Lys Gly Arg Pro Asn Lys Leu Glu Arg
                 305                 310                 315

 Asp Glu Val Val Gln Val Phe Asp Thr Ser Gln Phe Phe Arg Glu
                 320                 325                 330

 Leu Gln Gln Phe Tyr Asn Ser Gln Gly Arg Leu Pro Asp Gly Arg
                 335                 340                 345

 Val Val Leu Cys Phe Gly Glu Glu Phe Pro Asp Met Ala Pro Leu
                 350                 355                 360

 Arg Ser Lys Leu Ile Leu Val Gln Ile Glu Gln Leu Tyr Val Arg
                 365                 370                 375

 Gln Leu Ala Glu Glu Ala Gly Lys Ser Cys Gly Ala Gly Ser Val
                 380                 385                 390

 Met Gln Ala Pro Glu Glu Pro Pro Pro Asp Gln Val Phe Arg Met
                 395                 400                 405

 Phe Pro Asp Ile Cys Ala Ser His Gln Arg Ser Phe Phe Arg Glu
                 410                 415                 420

 Asn Gln Gln Ile Thr Val
                 425

<210> 6228
<211> 1402
<212> DNA
<213> Homo sapien

<400> 6228
 tggggccgga gaggcggcga ggcggcggcg gcggcggcaa gatggcggac 50

 ttcctgccgt cgcggtccgt gctgtccgtg tgcttccccg gctgcctgct 100

 gacgagtggc gaggccgagc agcaacgcaa gtccaaggag atcgacaaat 150

 gcctgtctcg ggaaaagacc tatgtgaagc ggctggtgaa gatcctgctg 200

 ctgggcgcgg gcgagagcgg caagtccacc ttcctgaagc agatgcggat 250

 catccacggg caggacttcg accagcgcgc gcgcgaggag ttccgcccca 300

 ccatctacag caacgtgatc aaaggtatga gggtgctggt tgatgctcga 350

 gagaagcttc atattccctg gggagacaac tcaaaccaac aacatggaga 400

 taagatgatg tcgtttgata cccgggcccc catggcagcc caaggaatgg 450

 tggaaacaag ggttttctta caatatcttc ctgctataag agcattatgg 500

 gcagacagcg gcatacagaa tgcctatgac cggcgtcgag aatttcaact 550

 gggtgaatct gtaaaatatt tcctggataa cttggataaa cttggagaac 600

 cagattatat tccatcacaa caagatattc tgcttgccag aagacccacc 650

 aaaggcatcc atgaatacga ctttgaaata aaaaatgttc ctttcaaaat 700

 gcttgatgta ggtggtcaga gatcagaaag gaaacgttgg tttgaatgtt 750

 tcgacagtgt gacatcaata cttttccttg tttcctcaag tgaatttgac 800

 caggtgctta tggaagatcg actgaccaat cgccttacag agtctctgaa 850

 catttttgaa acaatcgtca ataaccgggt tttcagcaat gtctccataa 900

 ttctgttctt aaacaagaca gacttgcttg aggagaaggt gcaaattgtg 950

 agcatcaaag actatttcct agaatttgaa ggggatcccc actgcttaag 1000

 agacgtccaa aaattcctgg tggaatgttt ccggaacaaa cgccgggacc 1050

 agcaacagaa gcccttatac caccacttca ccactgctat caacacggag 1100

 aacatccgcc ttgttttccg cgacgtgaag gatactattc tgcatgacaa 1150

 cctcaagcag cttatgctac agtgatgtac aaaagacttg ctgttttaat 1200

 atctttttgt gtttttgatg ttttctgttt gttttgtttt ttaaaatagc 1250

 agtttacaac cagaattaga acaatcttaa ttctacgttt aacttcttga 1300

 aaatcttagt actttttctg cggcctttgg tttgtggctg aaagctgttg 1350

 agtgactcat cgccaagatt tgctgtaatg caggctttga tctgtttcac 1400

 cc 1402

<210> 6229
<211> 377
<212> PRT
<213> Homo sapien

<400> 6229
 Met Ala Asp Phe Leu Pro Ser Arg Ser Val Leu Ser Val Cys Phe
   1               5                  10                  15

 Pro Gly Cys Leu Leu Thr Ser Gly Glu Ala Glu Gln Gln Arg Lys
                  20                  25                  30

 Ser Lys Glu Ile Asp Lys Cys Leu Ser Arg Glu Lys Thr Tyr Val
                  35                  40                  45

 Lys Arg Leu Val Lys Ile Leu Leu Leu Gly Ala Gly Glu Ser Gly
                  50                  55                  60

 Lys Ser Thr Phe Leu Lys Gln Met Arg Ile Ile His Gly Gln Asp
                  65                  70                  75

 Phe Asp Gln Arg Ala Arg Glu Glu Phe Arg Pro Thr Ile Tyr Ser
                  80                  85                  90

 Asn Val Ile Lys Gly Met Arg Val Leu Val Asp Ala Arg Glu Lys
                  95                 100                 105

 Leu His Ile Pro Trp Gly Asp Asn Ser Asn Gln Gln His Gly Asp
                 110                 115                 120

 Lys Met Met Ser Phe Asp Thr Arg Ala Pro Met Ala Ala Gln Gly
                 125                 130                 135

 Met Val Glu Thr Arg Val Phe Leu Gln Tyr Leu Pro Ala Ile Arg
                 140                 145                 150

 Ala Leu Trp Ala Asp Ser Gly Ile Gln Asn Ala Tyr Asp Arg Arg
                 155                 160                 165

 Arg Glu Phe Gln Leu Gly Glu Ser Val Lys Tyr Phe Leu Asp Asn
                 170                 175                 180

 Leu Asp Lys Leu Gly Glu Pro Asp Tyr Ile Pro Ser Gln Gln Asp
                 185                 190                 195

 Ile Leu Leu Ala Arg Arg Pro Thr Lys Gly Ile His Glu Tyr Asp
                 200                 205                 210

 Phe Glu Ile Lys Asn Val Pro Phe Lys Met Leu Asp Val Gly Gly
                 215                 220                 225

 Gln Arg Ser Glu Arg Lys Arg Trp Phe Glu Cys Phe Asp Ser Val
                 230                 235                 240

 Thr Ser Ile Leu Phe Leu Val Ser Ser Ser Glu Phe Asp Gln Val
                 245                 250                 255

 Leu Met Glu Asp Arg Leu Thr Asn Arg Leu Thr Glu Ser Leu Asn
                 260                 265                 270

 Ile Phe Glu Thr Ile Val Asn Asn Arg Val Phe Ser Asn Val Ser
                 275                 280                 285

 Ile Ile Leu Phe Leu Asn Lys Thr Asp Leu Leu Glu Glu Lys Val
                 290                 295                 300

 Gln Ile Val Ser Ile Lys Asp Tyr Phe Leu Glu Phe Glu Gly Asp
                 305                 310                 315

 Pro His Cys Leu Arg Asp Val Gln Lys Phe Leu Val Glu Cys Phe
                 320                 325                 330

 Arg Asn Lys Arg Arg Asp Gln Gln Gln Lys Pro Leu Tyr His His
                 335                 340                 345

 Phe Thr Thr Ala Ile Asn Thr Glu Asn Ile Arg Leu Val Phe Arg
                 350                 355                 360

 Asp Val Lys Asp Thr Ile Leu His Asp Asn Leu Lys Gln Leu Met
                 365                 370                 375

 Leu Gln


<210> 6230
<211> 2003
<212> DNA
<213> Homo sapien

<400> 6230
 gctcgtccga gtacatgtga gcggtaatcg cccctgcagc tggttatcct 50

 gacattatgc actccgaagc agaagaatcc aaggaaggcc taggcttaaa 100

 cactggcata tatggagaga acagttgcca ctcgactcag agattgagta 150

 gacacccaaa gaactgcagt tcttaagcct taggagaagc gagagaaatg 200

 gcagtggcca cagatgtctt taattccaaa aacctggccg ttcaggcaca 250

 aaagaagatc ttgggtaaaa tggtgtccaa atccatcgcc accaccttaa 300

 tagacgacac aagtagtgag gtgctggatg agctctacag agtgaccagg 350

 gagtacaccc aaaacaagaa ggaggcagag aagatcatca agaacctcat 400

 caagacagtc atcaagctgg ccattcttta taggaataat cagtttaatc 450

 aagatgagct agcattgatg gagaaattta agaagaaagt tcatcagctt 500

 gctatgaccg tggtcagttt ccatcaggtg gattatacct ttgaccggaa 550

 tgtgttatcc aggctgttaa atgaatgcag agagatgctg caccaaatca 600

 ttcagcgcca cctcactgcc aagtcacatg gacgggttaa taatgtgttt 650

 gatcattttt cagattgtga atttttggct gccttgtata atccttttgg 700

 gaattttaaa ccccacttac aaaaactatg tgatggtatc aacaaaatgt 750

 tggatgaaga gaacatatga gcacatgagt taagattgtg actgatcatg 800

 atttatttga agatggagca ctgctgattt atgaaggaaa aaagaagaat 850

 tttctaaaga ttacacatat ttcagaaaga ctttacccaa ttcagttgtc 900

 agacataatg atttatttga aggcttgttt tatttgaaga aaagcatatt 950

 gccaaaaatt ctggttaaaa gcttcctaac gggtaacaga ccatgggaga 1000

 gatatgtggt tgggtaatgc aaatgtagtt atacaaagaa aaatacagat 1050

 gtctccagac ctgaggactt tttaataggg cagttgttgt gttggtggca 1100

 cattggatat ttctaacatg tacaaagcta tgtattttga tttactttca 1150

 tttcttgcta tgtatatgta cttttcttaa aatgccaaga actttctctt 1200

 gctatcattg ctccttttga aacaattcaa ttttcatgtc tacagctgac 1250

 tgttttgtta agattgagtc atcgacattc aggatttaag tctgaggtag 1300

 tcaaccctca ggaaaaaaaa atggcttatc tgaaatcagt actgtggaaa 1350

 tgaactatat tagctattat gaataatgtc cagtataaga atatgcttct 1400

 ggaattgagt tctcctttta agtaccaatg atacttaaat ttctcagaaa 1450

 tgtaatggtg tgtcattgcc ttgaaatgct tgcttagggc ttcttttatg 1500

 ttatcttaaa aagtgctggt gaattttcca ttttttacat ccatttcaca 1550

 tgtaagagac acaaaagtct agattggtct tgatattgag ataataaaaa 1600

 gtaagtagca ttaagaaagg taacaatctt cattctacag atgaactcat 1650

 tgaaacaatt taggggaatg aggggcaaaa ggggagaaat actgctaaag 1700

 aacatgagca taaaaatgcg tgcgtttcag tgtttaagaa ggcttgataa 1750

 agaatgtcac ttttttattt aactgataag atttttgtta ttttttactt 1800

 tgataagtaa accaaagaat atttgtattt caagcagttt gtgtggtgtt 1850

 tctatataat tttctgtgta taaataataa agtaggcatt tgtttatttt 1900

 gtaaaaaaga aatgaaaatc tgctggccag ctatgtcctc taggaaatga 1950

 cagacccaac caccagcaat aaacatttcc attgtcaaaa aaaaaaaaaa 2000

 aaa 2003

<210> 6231
<211> 190
<212> PRT
<213> Homo sapien

<400> 6231
 Met Ala Val Ala Thr Asp Val Phe Asn Ser Lys Asn Leu Ala Val
   1               5                  10                  15

 Gln Ala Gln Lys Lys Ile Leu Gly Lys Met Val Ser Lys Ser Ile
                  20                  25                  30

 Ala Thr Thr Leu Ile Asp Asp Thr Ser Ser Glu Val Leu Asp Glu
                  35                  40                  45

 Leu Tyr Arg Val Thr Arg Glu Tyr Thr Gln Asn Lys Lys Glu Ala
                  50                  55                  60

 Glu Lys Ile Ile Lys Asn Leu Ile Lys Thr Val Ile Lys Leu Ala
                  65                  70                  75

 Ile Leu Tyr Arg Asn Asn Gln Phe Asn Gln Asp Glu Leu Ala Leu
                  80                  85                  90

 Met Glu Lys Phe Lys Lys Lys Val His Gln Leu Ala Met Thr Val
                  95                 100                 105

 Val Ser Phe His Gln Val Asp Tyr Thr Phe Asp Arg Asn Val Leu
                 110                 115                 120

 Ser Arg Leu Leu Asn Glu Cys Arg Glu Met Leu His Gln Ile Ile
                 125                 130                 135

 Gln Arg His Leu Thr Ala Lys Ser His Gly Arg Val Asn Asn Val
                 140                 145                 150

 Phe Asp His Phe Ser Asp Cys Glu Phe Leu Ala Ala Leu Tyr Asn
                 155                 160                 165

 Pro Phe Gly Asn Phe Lys Pro His Leu Gln Lys Leu Cys Asp Gly
                 170                 175                 180

 Ile Asn Lys Met Leu Asp Glu Glu Asn Ile
                 185                 190

<210> 6232
<211> 1406
<212> DNA
<213> Homo sapien

<400> 6232
 ggcacgaggg cgcgcaaggc accggtggca gcggcgacgg cagctgcgac 50

 agcaacccct gctgggccga aactgggcag agcggagcag acgtctgaag 100

 cagcgcgagt gaggcgcgag ggtagcgccc gcgcccggga agacccctcg 150

 gcgcgaaccg gcagcccagc cccgggtccc ggttcccaag gccccgcctc 200

 tagggcctgg ggactaatcg gattgagagc gcgccggccc gggccgcgaa 250

 ctcgccaatt gcggagggcg gtggccaccg cccaatccgg agcagacagg 300

 tgcgaggtcc ggaaggcgga ggccaatcgg cggcggttgc gacctgctgg 350

 ggcaggtctc ggccaataag gaggctcgag tgacatcttc gcgcaccaat 400

 cgggagtgag ggagcattcg tgcccgctcg cccttccggc cagacctcta 450

 tttaccaggg gcgtgcagcc cgcttgccaa tcagagcgcg gctgagcggc 500

 cccgcagcca acccccgagg agcggccggc tggcgtccgc cgcgcccagg 550

 agttggggat gtcctacaaa cccatcgccc ctgctcccag cagcacccct 600

 ggctccagca cccctgggcc gggcaccccg gtccctacag gaagcgtccc 650

 gtcgccgtcg ggctcagtgc caggagccgg cgctcctttc agaccgctgt 700

 ttaacgactt tggaccgcct tccatgggct acgtgcaggc gatgaagcca 750

 cccggcgccc agggctccca gagcacctac acggacctgc tgtcagtcat 800

 agaggagatg ggcaaagaga tccggcctac ctatgctggc agcaagagcg 850

 ccatggagcg cctgaagaga ggtatcatcc atgcccgggc cctagtcaga 900

 gagtgcctgg cagagacaga gcggaacgcc cgcacgtaac aggaagcgcc 950

 tcggcctcag cgtctggacc tatccggcca ctgcagagca cccgcttctc 1000

 cctggccttc atcccgagtt gcactaacca tcctgggctt cctgtcctgt 1050

 gtcccttggt gggtcccctc caggaaccaa ggagtggccc tccaggtggc 1100

 agcactaagg acaccccccc acaacaagag ttagcagcga ggtccccatg 1150

 agtcccaccc atgacctgcc gacagtgttg cccaccggaa cttttgtggc 1200

 ccctaccgct cagcccttcc cagcacttct cccactttgt cccgagcctc 1250

 cttctccccc agcaggggca caggcctggc acctccctgc cttgtgtcct 1300

 gagccatagt gactctttta tctgtgtgtc ttttgctaaa tatgcccttt 1350

 ttatattaat aaaagatgat ttggagttgt gctctcaaaa aaaaaaaaaa 1400

 aaaaaa 1406

<210> 6233
<211> 126
<212> PRT
<213> Homo sapien

<400> 6233
 Met Ser Tyr Lys Pro Ile Ala Pro Ala Pro Ser Ser Thr Pro Gly
   1               5                  10                  15

 Ser Ser Thr Pro Gly Pro Gly Thr Pro Val Pro Thr Gly Ser Val
                  20                  25                  30

 Pro Ser Pro Ser Gly Ser Val Pro Gly Ala Gly Ala Pro Phe Arg
                  35                  40                  45

 Pro Leu Phe Asn Asp Phe Gly Pro Pro Ser Met Gly Tyr Val Gln
                  50                  55                  60

 Ala Met Lys Pro Pro Gly Ala Gln Gly Ser Gln Ser Thr Tyr Thr
                  65                  70                  75

 Asp Leu Leu Ser Val Ile Glu Glu Met Gly Lys Glu Ile Arg Pro
                  80                  85                  90

 Thr Tyr Ala Gly Ser Lys Ser Ala Met Glu Arg Leu Lys Arg Gly
                  95                 100                 105

 Ile Ile His Ala Arg Ala Leu Val Arg Glu Cys Leu Ala Glu Thr
                 110                 115                 120

 Glu Arg Asn Ala Arg Thr
                 125

<210> 6234
<211> 1238
<212> DNA
<213> Homo sapien

<400> 6234
 gaattcgagg atccgggtac catgggagga aaacttcttc ctggcctggg 50

 ctccgtgccg ctctgtttgc caaccgtcca gtcccgccta ccagtgccgg 100

 gcgctcccca cccctccccc ggctcccccg gtgtccgcca tggccaaagc 150

 ctacgaccac ctcttcaagt tgctgctgat cggggactcg ggggtgggca 200

 agacttgtct gatcattcgc tttgcagagg acaacttcaa caacacttac 250

 atctccacca tcggaattga tttcaagatc cgcactgtgg atatagaggg 300

 gaagaagatc aaactacaag tctgggacac ggctggccaa gagcggttca 350

 agacaataac tactgcctac taccgtggag ccatgggcat tatcctagta 400

 tacgacatca cggatgagaa atctttcgag aatattcaga actggatgaa 450

 aagcatcaag gagaatgcct cggctggggt ggagcgcctc ttgctgggga 500

 acaaatgtga catggaggcc aagaggaagg tgcagaagga gcaggccgat 550

 aagttggctc gagagcatgg aatccgattt ttcgaaacta gtgctaaatc 600

 cagtatgaat gtggatgagg cttttagttc cctggcccgg gacatcttgc 650

 tcaagtcagg aggccggaga tcaggaaacg gcaacaagcc tcccagtact 700

 gacctgaaaa cttgtgacaa gaagaacacc aacaagtgct ccctgggctg 750

 aggacccttt cttgcctccc caccccggaa gctgaacctg agggagacaa 800

 cggcagaggg agtgagcagg ggagaaatag cagaggggct tggagggtca 850

 cataggtaga tggtaaagag aatgaggaga aaaaggagaa aagggaaaag 900

 cagaaaggaa aaaaaggaag agagaggaag ggagaaggga gaggaatgaa 950

 ttgaggaagt gaaagaaggc aaggaggtag gaagagaggg aggaggaaag 1000

 gaaggagaga gatgcctcag gcttcagacc ttacctgggt tttcagggca 1050

 aacataaatg taaatacact gatttattct gttactagat caggttttag 1100

 ggtcctgcaa aaggctagct cggcactaca ctagggaatt tgctcctgtt 1150

 ctgtcacttg tcatggtctt tcttggtatt aaaggccacc atttgcacaa 1200

 aaaaaaaaaa aaaccatggt acccggatcc tcgaattc 1238

<210> 6235
<211> 203
<212> PRT
<213> Homo sapien

<400> 6235
 Met Ala Lys Ala Tyr Asp His Leu Phe Lys Leu Leu Leu Ile Gly
   1               5                  10                  15

 Asp Ser Gly Val Gly Lys Thr Cys Leu Ile Ile Arg Phe Ala Glu
                  20                  25                  30

 Asp Asn Phe Asn Asn Thr Tyr Ile Ser Thr Ile Gly Ile Asp Phe
                  35                  40                  45

 Lys Ile Arg Thr Val Asp Ile Glu Gly Lys Lys Ile Lys Leu Gln
                  50                  55                  60

 Val Trp Asp Thr Ala Gly Gln Glu Arg Phe Lys Thr Ile Thr Thr
                  65                  70                  75

 Ala Tyr Tyr Arg Gly Ala Met Gly Ile Ile Leu Val Tyr Asp Ile
                  80                  85                  90

 Thr Asp Glu Lys Ser Phe Glu Asn Ile Gln Asn Trp Met Lys Ser
                  95                 100                 105

 Ile Lys Glu Asn Ala Ser Ala Gly Val Glu Arg Leu Leu Leu Gly
                 110                 115                 120

 Asn Lys Cys Asp Met Glu Ala Lys Arg Lys Val Gln Lys Glu Gln
                 125                 130                 135

 Ala Asp Lys Leu Ala Arg Glu His Gly Ile Arg Phe Phe Glu Thr
                 140                 145                 150

 Ser Ala Lys Ser Ser Met Asn Val Asp Glu Ala Phe Ser Ser Leu
                 155                 160                 165

 Ala Arg Asp Ile Leu Leu Lys Ser Gly Gly Arg Arg Ser Gly Asn
                 170                 175                 180

 Gly Asn Lys Pro Pro Ser Thr Asp Leu Lys Thr Cys Asp Lys Lys
                 185                 190                 195

 Asn Thr Asn Lys Cys Ser Leu Gly
                 200

<210> 6236
<211> 1610
<212> DNA
<213> Homo sapien

<400> 6236
 ggcacgaggg agagaactag tctcgagttt tttttttttt ttttttgaca 50

 agatggcggc aggaggcagt ggcgttggtg ggaagcgcag ctcgaaaagc 100

 gatgccgatt ctggtttcct ggggctgcgg cccacttcgg tggacccagc 150

 gctgaggcgg cggcggcgag gcccaagaaa taagaagcgg ggctggcggc 200

 ggcttgctca ggagccgctg gggctggagg ttgaccagtt cctggaagac 250

 gtgcggctac aggagcgcac gagcggtggc ttgttgtcag aggccccaaa 300

 tgaaaaactc ttcttcgtgg acactggctc caaggaaaaa gggctgacaa 350

 agaagagaac caaagtccag aagaagtcac tgcttctcaa gaaacccctt 400

 cgggttgacc tcatcctcga gaacacatcc aaagtccctg cccccaaaga 450

 cgtcctcgcc caccaggtcc ccaacgccaa gaagctcagg cggaaggagc 500

 agctatggga gaagctggcc aagcagggcg agctgccccg ggaggtgcgc 550

 agggcccagg cccggctcct caacccttct gcaacaaggg ccaagcccgg 600

 gccccaggac accgtagagc ggcccttcta cgacctctgg gcctcagaca 650

 accccctgga caggccgttg gttggccagg atgagttttt cctggagcag 700

 accaagaaga aaggagtgaa gcggccagca cgcctgcaca ccaagccgtc 750

 ccaggcgccc gccgtggagg tggcgcctgc cggagcttcc tacaatccat 800

 cctttgaaga ccaccagacc ctgctctcag cggcccacga ggtggagttg 850

 cagcggcaga aggaggcgga gaagctggag cggcagctgg ccctgcccgc 900

 cacggagcag gccgccaccc aggagtccac attccaggag ctgtgcgagg 950

 ggctgctgga ggagtcggat ggtgaggggg agccaggcca gggcgagggg 1000

 ccggaggctg gggatgccga ggtctgtccc acgcccgccc gcctggccac 1050

 cacagagaag aagacggagc agcagcggcg gcgggagaag gctgtgcaca 1100

 ggctgcgggt acagcaggcc gcgttgcggg ccgcccggct ccggcaccag 1150

 gagctgttcc ggctgcgcgg gatcaaggcc caggtggccc tgaggctggc 1200

 ggagctggcg cggcggcgga ggcggcggca ggcgcggcgg gaggctgagg 1250

 ctgacaagcc ccgaaggctg ggacggctca agtaccaggc acctgacatc 1300

 gacgtgcagc tgagctcgga gctgacagac tcgctcagga ccctgaagcc 1350

 cgagggcaac atccttcgag accggttcaa gagcttccag aggaggaata 1400

 tgatcgagcc tcgagagaga gccaagttca aacgcaagta caaggtgaag 1450

 ctggtggaga agcgggcgtt ccgtgagatc cagttgtagc tgccatcaga 1500

 tgccggagac tcgcccttca ataaaaaatc tcttctagct gaaaaaaaaa 1550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1600

 aaaaaaaaaa 1610

<210> 6237
<211> 478
<212> PRT
<213> Homo sapien

<400> 6237
 Met Ala Ala Gly Gly Ser Gly Val Gly Gly Lys Arg Ser Ser Lys
   1               5                  10                  15

 Ser Asp Ala Asp Ser Gly Phe Leu Gly Leu Arg Pro Thr Ser Val
                  20                  25                  30

 Asp Pro Ala Leu Arg Arg Arg Arg Arg Gly Pro Arg Asn Lys Lys
                  35                  40                  45

 Arg Gly Trp Arg Arg Leu Ala Gln Glu Pro Leu Gly Leu Glu Val
                  50                  55                  60

 Asp Gln Phe Leu Glu Asp Val Arg Leu Gln Glu Arg Thr Ser Gly
                  65                  70                  75

 Gly Leu Leu Ser Glu Ala Pro Asn Glu Lys Leu Phe Phe Val Asp
                  80                  85                  90

 Thr Gly Ser Lys Glu Lys Gly Leu Thr Lys Lys Arg Thr Lys Val
                  95                 100                 105

 Gln Lys Lys Ser Leu Leu Leu Lys Lys Pro Leu Arg Val Asp Leu
                 110                 115                 120

 Ile Leu Glu Asn Thr Ser Lys Val Pro Ala Pro Lys Asp Val Leu
                 125                 130                 135

 Ala His Gln Val Pro Asn Ala Lys Lys Leu Arg Arg Lys Glu Gln
                 140                 145                 150

 Leu Trp Glu Lys Leu Ala Lys Gln Gly Glu Leu Pro Arg Glu Val
                 155                 160                 165

 Arg Arg Ala Gln Ala Arg Leu Leu Asn Pro Ser Ala Thr Arg Ala
                 170                 175                 180

 Lys Pro Gly Pro Gln Asp Thr Val Glu Arg Pro Phe Tyr Asp Leu
                 185                 190                 195

 Trp Ala Ser Asp Asn Pro Leu Asp Arg Pro Leu Val Gly Gln Asp
                 200                 205                 210

 Glu Phe Phe Leu Glu Gln Thr Lys Lys Lys Gly Val Lys Arg Pro
                 215                 220                 225

 Ala Arg Leu His Thr Lys Pro Ser Gln Ala Pro Ala Val Glu Val
                 230                 235                 240

 Ala Pro Ala Gly Ala Ser Tyr Asn Pro Ser Phe Glu Asp His Gln
                 245                 250                 255

 Thr Leu Leu Ser Ala Ala His Glu Val Glu Leu Gln Arg Gln Lys
                 260                 265                 270

 Glu Ala Glu Lys Leu Glu Arg Gln Leu Ala Leu Pro Ala Thr Glu
                 275                 280                 285

 Gln Ala Ala Thr Gln Glu Ser Thr Phe Gln Glu Leu Cys Glu Gly
                 290                 295                 300

 Leu Leu Glu Glu Ser Asp Gly Glu Gly Glu Pro Gly Gln Gly Glu
                 305                 310                 315

 Gly Pro Glu Ala Gly Asp Ala Glu Val Cys Pro Thr Pro Ala Arg
                 320                 325                 330

 Leu Ala Thr Thr Glu Lys Lys Thr Glu Gln Gln Arg Arg Arg Glu
                 335                 340                 345

 Lys Ala Val His Arg Leu Arg Val Gln Gln Ala Ala Leu Arg Ala
                 350                 355                 360

 Ala Arg Leu Arg His Gln Glu Leu Phe Arg Leu Arg Gly Ile Lys
                 365                 370                 375

 Ala Gln Val Ala Leu Arg Leu Ala Glu Leu Ala Arg Arg Arg Arg
                 380                 385                 390

 Arg Arg Gln Ala Arg Arg Glu Ala Glu Ala Asp Lys Pro Arg Arg
                 395                 400                 405

 Leu Gly Arg Leu Lys Tyr Gln Ala Pro Asp Ile Asp Val Gln Leu
                 410                 415                 420

 Ser Ser Glu Leu Thr Asp Ser Leu Arg Thr Leu Lys Pro Glu Gly
                 425                 430                 435

 Asn Ile Leu Arg Asp Arg Phe Lys Ser Phe Gln Arg Arg Asn Met
                 440                 445                 450

 Ile Glu Pro Arg Glu Arg Ala Lys Phe Lys Arg Lys Tyr Lys Val
                 455                 460                 465

 Lys Leu Val Glu Lys Arg Ala Phe Arg Glu Ile Gln Leu
                 470                 475

<210> 6238
<211> 2998
<212> DNA
<213> Homo sapien

<400> 6238
 tgttcagatt caattaggat ttgcagctga gttttccaat gtcatgatca 50

 tctatacaag tatagtttac aaaccaccgg agataataat gtgtgatgcc 100

 tacgttactg attttccact tgatctagat attgatccaa aagatgcaaa 150

 taaaggcaca cctgaagaaa ctggcagcta cttggtatca aaggatcttc 200

 ccaagcattg cctctatacc agactcagtt cactgcaaaa attaaaggaa 250

 catctagtct tcacagtatg tttatcatat cagtactcag gattggaaga 300

 tactgtagag gacaagcagg aagtgaatgt tgggaaacct ctcattgcta 350

 aattagacat gcatcgaggt ttgggaagga agacttgctt tcaaacttgt 400

 cttatgtcta atggtcctta ccagagttct gcagccacct caggaggagc 450

 agggcattat cactcattgc aagacccatt ccatggtgtt taccattcac 500

 atcctggtaa tccaagtaat gttacaccag cagatagctg tcattgcagc 550

 cggactccag atgcatttat ttcaagtttc gctcaccatg cttcatgtca 600

 ttttagtaga agtaatgtgc cagtagagac aactgatgaa ataccattta 650

 gtttctctga caggctcaga atttctgaaa aatgacctcc ttgtttttga 700

 aagttagcat aattttagat gcctgtgaaa tagtactgca cttacataaa 750

 gtgagacatt gtgaaaaggc aaatttgtat atgtagagaa agaatagtag 800

 taactgtttc atagcaaact tcaggacttt gagatgttga aattacatta 850

 tttaattaca gacttcctct ttctaagatt ttgtgaattg gttgaatagt 900

 tctatacaaa tgaagtatgg aggtgtgtat gtttatatgt atataacaaa 950

 atattttcat tgtgaccact ctgaagtaag agcaatggga atggcattat 1000

 tgtagaataa gtcattgtat ttttaacacc agaaagaacc ttgccgatca 1050

 ccaggcataa cctaatttta tccatggaag aaacacagaa aggcatctaa 1100

 gttagagctg gcaccagaac tgagacctcc agaaatctat tccagtattt 1150

 tttccactac acaactgcct tcctgacagg ttctgagata agtgttatgt 1200

 ttgtagatag agtgaaatat atttatatat atataaatat atacagatac 1250

 atatctgtgt attatctcaa ggaatgtaca aactttagtt tttgattata 1300

 aggacttcac tgcaagtttt agttaagagg tttgtatata aatctgttat 1350

 agaacaggct gaaatttctt gttcataaga ttatgaaacc acatgagaag 1400

 tgataaaatg tttgttaaag ctagatagag gttaagaatc aagatataat 1450

 ggataatttt catagctgcc tatcagaatt tcccaaatat ttagcatctt 1500

 ccttgataat atgtattttc ttcttgaatt tcactggcct aatgagataa 1550

 tactcttatc tttggctcta cctaaaagtt ggttaaaaat gcaattggca 1600

 ttaacaagga aaaatactga attagtaatt ttaaaagtct cacaaagaaa 1650

 atcccaggcc tagatggctg cattgttgaa ttctgccaaa cattaaaatt 1700

 agcactaatt ttttgcacac tgtttctaaa agtaggagag gaaagaacac 1750

 ttcccaactt actctaggtc agtattaccc tgatactaga ctagacatca 1800

 caagaaaact ataagccaat attccttatt aatacaaaca caaaaatcat 1850

 taacaaaaat attagcaaac tgaatccagc aacctataaa aaggattcta 1900

 tatcatgacc aagtggaatt tatcccagga attcaaggtt ggttcaacat 1950

 ctaaaaatca aataagctaa tatacagtca gttctcatta ttcacagtaa 2000

 ttatgttcta cagaatattc tcccataaac actgaattaa atatggaaca 2050

 actgctttta ggagaaagtg tatttgtgta tatgtgtgta tacatatgtt 2100

 tatctcacac acattatgag cttgaattct taattcatcc tagcaaattc 2150

 taccttattt tacagaagtg aaagtgaggt atcagaagtg ttaagtgaca 2200

 tgcctgaggc acccccctaa caggtgtcag agctgaaatt caaaccccat 2250

 ccagctggcc ccggagccag agcttcttgt actacacaga attgcccctg 2300

 ccatttccac cctccagtca tttctctatg agactgaagc aggaaggcag 2350

 agcatcatct tgttcagcct cagctgggaa catgtgtact gggtgactca 2400

 aatttttcac ccatttacac atatccacaa atgactgcaa aagtgccacg 2450

 gatatcaatt tgagggttat aaattttagc aagttggtaa attcacaaat 2500

 acataacctt gaataatgag gatcaactgt accatattta ataaagcaca 2550

 aaacccacac agattgtctt attacagcat ttgataaaat ccaaaactct 2600

 ttcataaaaa cactcaacaa acttaggaat aaaaggaatc ttcctagata 2650

 tgataaatat aacatctatg aaaagcccac acctaacatt atacttcatg 2700

 gtgatagact gaaggctgaa tgttttcccc ttaagattgg gaagaaggac 2750

 aaggatgttc actcggcact acttctattc agcattgtac ttgaagttct 2800

 agccacagca gttaggttag gaattcaagg tttgttcaac atctaaaaat 2850

 caaataagct aataaagaaa agaggtttat actgcaaaag aagtgaaact 2900

 atatgtattc acagttgata catagttgta tatagaaaat gctaaagaat 2950

 ccataaaaag taataaatga gttcaacagg ttaaaaaaaa aaaaaaaa 2998

<210> 6239
<211> 2414
<212> DNA
<213> Homo sapien

<400> 6239
 cccgcgtgca tacggttgcc ggcatggcac attacaactt caagaaaatt 50

 acggtggtgc cgtccgccaa ggacttcata gacctcacgt tgtcgaagac 100

 tcaacgaaag actccaaccg ttattcataa acattaccaa atacatcgca 150

 ttagacattt ttacatgaga aaagtcaaat ttactcaaca gaattaccat 200

 gatagacttt cacaaattct aacagatttc cccaaattgg atgatattca 250

 tccgttctat gctgatttga tgaatattct ctacgacaag gatcattaca 300

 agttggctct ggggcaaata aatattgcca aaaatttagt ggacaatgtt 350

 gctaaagatt atgtgcgact gatgaagtat ggcgactctc tctaccgctg 400

 caaacagctg aagcgtgcgg ccctgggacg gatgtgcaca gtgatcaaga 450

 ggcagaagca gagtttggag tatttggagc aagtgcgtca gcatttatcc 500

 cgtttgccaa ccattgatcc gaataccagg accctgcttt tgtgtgggta 550

 cccaaatgtt gggaagtcca gcttcatcaa caaggtgacg agagcagacg 600

 tggatgtcca gccctatgcg ttcacaacca agtctctgtt tgttgggcac 650

 atggattata agtatctacg ttggcaggtt gtagacactc ctgggatcct 700

 ggaccaccct ctggaggata ggaacaccat cgagatgcag gccatcactg 750

 ccctggccca cctccgtgct gcggtcctgt atgtgatgga tttgtctgag 800

 cagtgtgggc atgggctgag ggagcagcta gaactcttcc agaacatcag 850

 acctctcttc atcaacaagc ctctcatagt tgtagccaac aaatgtgatg 900

 tgaagagaat agctgaactt tctgaagatg atcagaaaat atttacagat 950

 ttgcagtctg aaggattccc tgtaatagag accagcaccc tgactgagga 1000

 aggtgttatt aaagttaaaa cagaggcttg cgataggctt ttggctcatc 1050

 gagtggaaac caaaatgaag ggaaataaag tgaatgaggt gctgaataga 1100

 ctgcacctgg ctatcccaac caggagggac gataaggaga ggcccccttt 1150

 catccctgaa ggagtggtgg ctcgcaggaa gaggatggaa actgaggagt 1200

 ccaggaagaa gagggaacga gatcttgagc tggaaatggg agatgattat 1250

 attttggatc ttcagaagta ctgggattta atgaatttgt ctgaaaaaca 1300

 tgataagata ccagaaatct gggaaggcca taatatagct gattatattg 1350

 atccagccat catgaagaaa ttggaagaat tagaaaaaga agaagagctg 1400

 agaacagctg ctggagagta tgacagtgta tctgagagtg aagacgaaga 1450

 gatgctggaa atccgacagc tggcaaagca aattcgagag aaaaagaagt 1500

 tgaaaattct ggagtccaaa gaaaagaata cacagggacc caggatgccg 1550

 cgaactgcta agaaggttca gaggacagtt ttggagaagg agatgcgtag 1600

 tcttggtgtt gacatggacg ataaagacga tgcccattac gcagtccagg 1650

 caagaagatc ccggagcatc actaggaaaa gaaagcggga agactctgct 1700

 cccccgtcct ctgtggcccg gagtgggagt tgctctcgaa ctccacgtga 1750

 cgtttctggt cttagggatg tcaagatggt gaagaaagcc aagactatga 1800

 agaatgctca gaagaagatg aatcggttgg ggaagaaagg ggaggcggat 1850

 agacacgtgt ttgatatgaa gcccaagcac ttgctgtctg ggaagaggaa 1900

 agctggtaaa aaggacagga gatagtatcc gtttggttgg cgtggcttcg 1950

 ctagagtgtt gctgtttatt tcctggtttg gtacagtatg gtttcatgaa 2000

 attggagctc tgtacaaact gaaaaagaca aaataagtaa agcacttgtt 2050

 gctttgctga aaactatggt taaccctata taggtgtggg aaatttttgt 2100

 cactgcataa tattacaaat attttgagta gacagtgttt ccacatttaa 2150

 tggagtatca gttgcttcag attttcagaa ctgggaagat ttactggtgt 2200

 aactgggttg tttttgatgg agaaaaacct tattttcttt tgtaagagct 2250

 gggagcaaac acgtttatga gtgtgtcgga atcccgtgct taaaatacgc 2300

 tcttaaatta ttttctagtc ttattttaca atgtctcatt gtagtctgtc 2350

 ttcaactatt ttatccaaaa taaacctcca gaagaaacta aaaaaaaaaa 2400

 aaaaaaaaaa aaaa 2414

<210> 6240
<211> 633
<212> PRT
<213> Homo sapien

<400> 6240
 Met Ala His Tyr Asn Phe Lys Lys Ile Thr Val Val Pro Ser Ala
   1               5                  10                  15

 Lys Asp Phe Ile Asp Leu Thr Leu Ser Lys Thr Gln Arg Lys Thr
                  20                  25                  30

 Pro Thr Val Ile His Lys His Tyr Gln Ile His Arg Ile Arg His
                  35                  40                  45

 Phe Tyr Met Arg Lys Val Lys Phe Thr Gln Gln Asn Tyr His Asp
                  50                  55                  60

 Arg Leu Ser Gln Ile Leu Thr Asp Phe Pro Lys Leu Asp Asp Ile
                  65                  70                  75

 His Pro Phe Tyr Ala Asp Leu Met Asn Ile Leu Tyr Asp Lys Asp
                  80                  85                  90

 His Tyr Lys Leu Ala Leu Gly Gln Ile Asn Ile Ala Lys Asn Leu
                  95                 100                 105

 Val Asp Asn Val Ala Lys Asp Tyr Val Arg Leu Met Lys Tyr Gly
                 110                 115                 120

 Asp Ser Leu Tyr Arg Cys Lys Gln Leu Lys Arg Ala Ala Leu Gly
                 125                 130                 135

 Arg Met Cys Thr Val Ile Lys Arg Gln Lys Gln Ser Leu Glu Tyr
                 140                 145                 150

 Leu Glu Gln Val Arg Gln His Leu Ser Arg Leu Pro Thr Ile Asp
                 155                 160                 165

 Pro Asn Thr Arg Thr Leu Leu Leu Cys Gly Tyr Pro Asn Val Gly
                 170                 175                 180

 Lys Ser Ser Phe Ile Asn Lys Val Thr Arg Ala Asp Val Asp Val
                 185                 190                 195

 Gln Pro Tyr Ala Phe Thr Thr Lys Ser Leu Phe Val Gly His Met
                 200                 205                 210

 Asp Tyr Lys Tyr Leu Arg Trp Gln Val Val Asp Thr Pro Gly Ile
                 215                 220                 225

 Leu Asp His Pro Leu Glu Asp Arg Asn Thr Ile Glu Met Gln Ala
                 230                 235                 240

 Ile Thr Ala Leu Ala His Leu Arg Ala Ala Val Leu Tyr Val Met
                 245                 250                 255

 Asp Leu Ser Glu Gln Cys Gly His Gly Leu Arg Glu Gln Leu Glu
                 260                 265                 270

 Leu Phe Gln Asn Ile Arg Pro Leu Phe Ile Asn Lys Pro Leu Ile
                 275                 280                 285

 Val Val Ala Asn Lys Cys Asp Val Lys Arg Ile Ala Glu Leu Ser
                 290                 295                 300

 Glu Asp Asp Gln Lys Ile Phe Thr Asp Leu Gln Ser Glu Gly Phe
                 305                 310                 315

 Pro Val Ile Glu Thr Ser Thr Leu Thr Glu Glu Gly Val Ile Lys
                 320                 325                 330

 Val Lys Thr Glu Ala Cys Asp Arg Leu Leu Ala His Arg Val Glu
                 335                 340                 345

 Thr Lys Met Lys Gly Asn Lys Val Asn Glu Val Leu Asn Arg Leu
                 350                 355                 360

 His Leu Ala Ile Pro Thr Arg Arg Asp Asp Lys Glu Arg Pro Pro
                 365                 370                 375

 Phe Ile Pro Glu Gly Val Val Ala Arg Arg Lys Arg Met Glu Thr
                 380                 385                 390

 Glu Glu Ser Arg Lys Lys Arg Glu Arg Asp Leu Glu Leu Glu Met
                 395                 400                 405

 Gly Asp Asp Tyr Ile Leu Asp Leu Gln Lys Tyr Trp Asp Leu Met
                 410                 415                 420

 Asn Leu Ser Glu Lys His Asp Lys Ile Pro Glu Ile Trp Glu Gly
                 425                 430                 435

 His Asn Ile Ala Asp Tyr Ile Asp Pro Ala Ile Met Lys Lys Leu
                 440                 445                 450

 Glu Glu Leu Glu Lys Glu Glu Glu Leu Arg Thr Ala Ala Gly Glu
                 455                 460                 465

 Tyr Asp Ser Val Ser Glu Ser Glu Asp Glu Glu Met Leu Glu Ile
                 470                 475                 480

 Arg Gln Leu Ala Lys Gln Ile Arg Glu Lys Lys Lys Leu Lys Ile
                 485                 490                 495

 Leu Glu Ser Lys Glu Lys Asn Thr Gln Gly Pro Arg Met Pro Arg
                 500                 505                 510

 Thr Ala Lys Lys Val Gln Arg Thr Val Leu Glu Lys Glu Met Arg
                 515                 520                 525

 Ser Leu Gly Val Asp Met Asp Asp Lys Asp Asp Ala His Tyr Ala
                 530                 535                 540

 Val Gln Ala Arg Arg Ser Arg Ser Ile Thr Arg Lys Arg Lys Arg
                 545                 550                 555

 Glu Asp Ser Ala Pro Pro Ser Ser Val Ala Arg Ser Gly Ser Cys
                 560                 565                 570

 Ser Arg Thr Pro Arg Asp Val Ser Gly Leu Arg Asp Val Lys Met
                 575                 580                 585

 Val Lys Lys Ala Lys Thr Met Lys Asn Ala Gln Lys Lys Met Asn
                 590                 595                 600

 Arg Leu Gly Lys Lys Gly Glu Ala Asp Arg His Val Phe Asp Met
                 605                 610                 615

 Lys Pro Lys His Leu Leu Ser Gly Lys Arg Lys Ala Gly Lys Lys
                 620                 625                 630

 Asp Arg Arg


<210> 6241
<211> 625
<212> DNA
<213> Homo sapien

<400> 6241
 cgcagccagg agccatgggc aacatctcct ctaacatctc ggccttccag 50

 tccctgcata tcgtcatgtt gggcttggac tcggccggca agaccacggt 100

 gctctaccgg ctcaagttca acgagttcgt gaacacggtg cccaccatcg 150

 gcttcaacac cgagaagatc aagctgagca acggcacggc caagggcatc 200

 agctgccact tctgggacgt gggcggccag gagaagctgc ggccgctgtg 250

 gaagtcctac agccgctgca cggacggcat catctacgtg gtggactcgg 300

 tggacgtgga ccggctggag gaggccaaga cggagctgca caaggtgacc 350

 aagttcgccg agaaccaggg cacgccgctg ctggtcatcg ccaacaagca 400

 ggacctgccc aagtcgctgc cggtggcaga gattgagaag cagctggcgc 450

 tgcacgagct tatcccggcc accacctatc acgtccagcc ggcgtgcgcc 500

 atcatcggcg agggcctcac cgagggcatg gacaagctct atgagatgat 550

 cctgaaacgc aggaagtccc tcaagcagaa gaagaagcgg taatgcgccc 600

 ggagcgaccg gggagcgagc gagtg 625

<210> 6242
<211> 192
<212> PRT
<213> Homo sapien

<400> 6242
 Met Gly Asn Ile Ser Ser Asn Ile Ser Ala Phe Gln Ser Leu His
   1               5                  10                  15

 Ile Val Met Leu Gly Leu Asp Ser Ala Gly Lys Thr Thr Val Leu
                  20                  25                  30

 Tyr Arg Leu Lys Phe Asn Glu Phe Val Asn Thr Val Pro Thr Ile
                  35                  40                  45

 Gly Phe Asn Thr Glu Lys Ile Lys Leu Ser Asn Gly Thr Ala Lys
                  50                  55                  60

 Gly Ile Ser Cys His Phe Trp Asp Val Gly Gly Gln Glu Lys Leu
                  65                  70                  75

 Arg Pro Leu Trp Lys Ser Tyr Ser Arg Cys Thr Asp Gly Ile Ile
                  80                  85                  90

 Tyr Val Val Asp Ser Val Asp Val Asp Arg Leu Glu Glu Ala Lys
                  95                 100                 105

 Thr Glu Leu His Lys Val Thr Lys Phe Ala Glu Asn Gln Gly Thr
                 110                 115                 120

 Pro Leu Leu Val Ile Ala Asn Lys Gln Asp Leu Pro Lys Ser Leu
                 125                 130                 135

 Pro Val Ala Glu Ile Glu Lys Gln Leu Ala Leu His Glu Leu Ile
                 140                 145                 150

 Pro Ala Thr Thr Tyr His Val Gln Pro Ala Cys Ala Ile Ile Gly
                 155                 160                 165

 Glu Gly Leu Thr Glu Gly Met Asp Lys Leu Tyr Glu Met Ile Leu
                 170                 175                 180

 Lys Arg Arg Lys Ser Leu Lys Gln Lys Lys Lys Arg
                 185                 190

<210> 6243
<211> 900
<212> DNA
<213> Homo sapien

<400> 6243
 gggactcggc ggaggatggg cttgctctca attttgcgca agttgaaaag 50

 tgcaccagac caggaggtga gaatacttct cctgggcttg gataatgctg 100

 gcaagaccac tcttctgaag cagcttgcat ctgaagacat cagccacatc 150

 acacctacac agggtttcaa catcaaaagt gtacaatcac aaggttttaa 200

 actgaatgta tgggacattg gtggacagag gaaaatcaga ccatactgga 250

 agaattattt tgaaaatacc gatattctta tatatgtaat cgacagtgca 300

 gacagaaaaa gatttgaaga gacgggtcag gaactagcgg aattactgga 350

 ggaagaaaaa ctaagttgtg tgccagtgct catctttgct aataagcagg 400

 atttgctcac agcagcccct gcctctgaaa ttgcagaagg actgaacctg 450

 cataccatcc gcgaccgagt ctggcagatc cagtcttgct cagctctcac 500

 aggagagggc gttcaggatg gcatgaactg ggtctgcaaa aatgtcaatg 550

 caaagaagaa ataaaatcta gacgaatgga gatgcaggag ctgcgggagc 600

 cgaattcggg ccttaaaaac actaatttgc tgctttctga ccaaatgttt 650

 ttcatctgtg tacactccag ctgtttgaag agagggaaca acacggttta 700

 gaaagaatcc ccattccagc agtagattta actgatctct gaggttcagt 750

 atcatttttc aaataaagga attatattat ttcctctgca taattgaaat 800

 agtattaaat gtctaaagca catgattaga aaatgagatc ttttaaatga 850

 gcaagagatt gcattgcagt ttagacaatt ccagtgggct ttttttttcg 900

<210> 6244
<211> 182
<212> PRT
<213> Homo sapien

<400> 6244
 Met Gly Leu Leu Ser Ile Leu Arg Lys Leu Lys Ser Ala Pro Asp
   1               5                  10                  15

 Gln Glu Val Arg Ile Leu Leu Leu Gly Leu Asp Asn Ala Gly Lys
                  20                  25                  30

 Thr Thr Leu Leu Lys Gln Leu Ala Ser Glu Asp Ile Ser His Ile
                  35                  40                  45

 Thr Pro Thr Gln Gly Phe Asn Ile Lys Ser Val Gln Ser Gln Gly
                  50                  55                  60

 Phe Lys Leu Asn Val Trp Asp Ile Gly Gly Gln Arg Lys Ile Arg
                  65                  70                  75

 Pro Tyr Trp Lys Asn Tyr Phe Glu Asn Thr Asp Ile Leu Ile Tyr
                  80                  85                  90

 Val Ile Asp Ser Ala Asp Arg Lys Arg Phe Glu Glu Thr Gly Gln
                  95                 100                 105

 Glu Leu Ala Glu Leu Leu Glu Glu Glu Lys Leu Ser Cys Val Pro
                 110                 115                 120

 Val Leu Ile Phe Ala Asn Lys Gln Asp Leu Leu Thr Ala Ala Pro
                 125                 130                 135

 Ala Ser Glu Ile Ala Glu Gly Leu Asn Leu His Thr Ile Arg Asp
                 140                 145                 150

 Arg Val Trp Gln Ile Gln Ser Cys Ser Ala Leu Thr Gly Glu Gly
                 155                 160                 165

 Val Gln Asp Gly Met Asn Trp Val Cys Lys Asn Val Asn Ala Lys
                 170                 175                 180

 Lys Lys


<210> 6245
<211> 884
<212> DNA
<213> Homo sapien

<400> 6245
 cgaggttcgg gtcgtggggc ggagggaaga gcgggcgggc gggaggcgcc 50

 ggcgccagac gcggagggaa ggagctacga gtagccgccg agaggccgcg 100

 gagccagcga cgaccgaccc agccgagccg ccgccgccgc cgcgccccca 150

 tggcggccgc caaggacact catgaggacc atgatacttc cactgagaat 200

 acagacgagt ccaaccatga ccctcagttt gagccaatag tttctcttcc 250

 tgagcaagaa attaaaacac tggaagaaga tgaagaggaa ctttttaaaa 300

 tgcgggcaaa actgttccga tttgcctctg agaacgatct cccagaatgg 350

 aaggagcgag gcactggtga cgtcaagctc ctgaagcaca aggagaaagg 400

 ggccatccgc ctcctcatgc ggagggacaa gaccctgaag atctgtgcca 450

 accactacat cacgccgatg atggagctga agcccaacgc aggtagcgac 500

 cgtgcctggg tctggaacac ccacgctgac ttcgccgacg agtgccccaa 550

 gccagagctg ctggccatcc gcttcctgaa tgctgagaat gcacagaaat 600

 tcaaaacaaa gtttgaagaa tgcaggaaag agatcgaaga gagagaaaag 650

 aaagcaggat caggcaaaaa tgatcatgcc gaaaaagtgg cggaaaagct 700

 agaagctctc tcggtgaagg aggagaccaa ggaggatgct gaggagaagc 750

 aataaatcgt cttattttat tttcttttcc tctctttcct ttcctttttt 800

 taaaaaattt taccctgccc ctctttttcg gtttgttttt attctttcat 850

 ttttacaagg gacgttatat aaagaactga actc 884

<210> 6246
<211> 201
<212> PRT
<213> Homo sapien

<400> 6246
 Met Ala Ala Ala Lys Asp Thr His Glu Asp His Asp Thr Ser Thr
   1               5                  10                  15

 Glu Asn Thr Asp Glu Ser Asn His Asp Pro Gln Phe Glu Pro Ile
                  20                  25                  30

 Val Ser Leu Pro Glu Gln Glu Ile Lys Thr Leu Glu Glu Asp Glu
                  35                  40                  45

 Glu Glu Leu Phe Lys Met Arg Ala Lys Leu Phe Arg Phe Ala Ser
                  50                  55                  60

 Glu Asn Asp Leu Pro Glu Trp Lys Glu Arg Gly Thr Gly Asp Val
                  65                  70                  75

 Lys Leu Leu Lys His Lys Glu Lys Gly Ala Ile Arg Leu Leu Met
                  80                  85                  90

 Arg Arg Asp Lys Thr Leu Lys Ile Cys Ala Asn His Tyr Ile Thr
                  95                 100                 105

 Pro Met Met Glu Leu Lys Pro Asn Ala Gly Ser Asp Arg Ala Trp
                 110                 115                 120

 Val Trp Asn Thr His Ala Asp Phe Ala Asp Glu Cys Pro Lys Pro
                 125                 130                 135

 Glu Leu Leu Ala Ile Arg Phe Leu Asn Ala Glu Asn Ala Gln Lys
                 140                 145                 150

 Phe Lys Thr Lys Phe Glu Glu Cys Arg Lys Glu Ile Glu Glu Arg
                 155                 160                 165

 Glu Lys Lys Ala Gly Ser Gly Lys Asn Asp His Ala Glu Lys Val
                 170                 175                 180

 Ala Glu Lys Leu Glu Ala Leu Ser Val Lys Glu Glu Thr Lys Glu
                 185                 190                 195

 Asp Ala Glu Glu Lys Gln
                 200

<210> 6247
<211> 1780
<212> DNA
<213> Homo sapien

<400> 6247
 tgggggtaca actcggccgt tgtcaccatg ccggtcgtcc ggaagatttt 50

 ccgtcgccgc cggggcgact cggagtcaga ggaagatgag caggactcag 100

 aggaggttcg attaaaactg gaagagacca gagaggtaca gaacttgagg 150

 aagaggccca acggggtgag tgctgtggcc ttgctggtgg gagagaaggt 200

 acaagaggag accactctag tggatgatcc ctttcagatg aagacaggtg 250

 gtatggtgga tatgaagaaa ctgaaggaaa ggggcaaaga taagatcagt 300

 gaggaggagg acctgcacct ggggacatcg ttttctgcag aaaccaaccg 350

 aagggatgag gatgcagaca tgatgaagta cattgagaca gagctaaaga 400

 agaggaaagg gatcgtggaa catgaggaac agaaagttaa gccaaagaat 450

 gcagaggact gtctttatga acttccagaa aacatccgtg tttcctcagc 500

 aaagaagacc gaggagatgc tttccaacca gatgctgagt ggcattcctg 550

 aggtggacct gggcatcgat gctaaaataa aaaatatcat ttccacggag 600

 gatgccaagg cccgtctgct ggcagagcag cagaacaaga agaaagacag 650

 cgagacctcc ttcgtgccta ccaacatggc tgtgaattat gtgcagcaca 700

 acagatttta tcatgaggag ctcaacgcgc ccatacggag aaacaaagaa 750

 gagcccaagg cccggccctt gagagtaggc gacacggaga agccagagcc 800

 tgagcggtcc cctcctaacc gcaagcgtcc tgctaacgag aaggcaactg 850

 atgactatca ttatgagaag ttcaagaaaa tgaataggcg gtactgagtt 900

 gtgcacagtg ggatgtaaat atcgccttcc tctccctata tccctcccat 950

 gaaaaatggc ttcctggccg ggcgtggtgg ctcacgcctg taatcccagc 1000

 actttgggag gccgaggtgg gcggatcacc tgaggtcggg agtttgagac 1050

 cagcctgacc aacatggaga aacccagtct ctactgaaaa tacagaaaag 1100

 ttagccaggc gtggtggcac atgcctgtaa tcccagctgc tcaggaggct 1150

 gaggcaggag aattgcttga acccaagagg cggaggttgt ggtgagccga 1200

 gattgcacct ttgtactcca gcctgggcaa cgagcaaaaa actctgtctc 1250

 aaagaaaaaa aaaaaagaaa gaaaaagaaa aatggcttcc aggacagagc 1300

 atgctcattt gctggcggac agttccagaa acagaccctg ttagtccttc 1350

 tacttacctg ctggattttt caagcactaa atttataact ttttgcaaca 1400

 aaataatgtg taattttcca tttgggggca aactctattc tggtgagcat 1450

 tattaaatct tgtttgtaaa tatattgtct ttctcttaat atttgctctg 1500

 ggtcaggaag aagctgttca cggtgtgata atactcttta gattgtgctt 1550

 tcattattat agatgcatca tgtcttctgc tttcacgtgt ctgggatggg 1600

 gtcagaaatg catcctccag ctgacagaaa aatccaggat gagatcagaa 1650

 ggatactggt gttttctgac ttttacaaaa ttacttgttt gttttcattt 1700

 aaaaaaaagc ataaactatg tttcttgtta ctattagaat tattaaattt 1750

 caaaatgaat ccaaaaaaaa aaaaaaaaaa 1780

<210> 6248
<211> 289
<212> PRT
<213> Homo sapien

<400> 6248
 Met Pro Val Val Arg Lys Ile Phe Arg Arg Arg Arg Gly Asp Ser
   1               5                  10                  15

 Glu Ser Glu Glu Asp Glu Gln Asp Ser Glu Glu Val Arg Leu Lys
                  20                  25                  30

 Leu Glu Glu Thr Arg Glu Val Gln Asn Leu Arg Lys Arg Pro Asn
                  35                  40                  45

 Gly Val Ser Ala Val Ala Leu Leu Val Gly Glu Lys Val Gln Glu
                  50                  55                  60

 Glu Thr Thr Leu Val Asp Asp Pro Phe Gln Met Lys Thr Gly Gly
                  65                  70                  75

 Met Val Asp Met Lys Lys Leu Lys Glu Arg Gly Lys Asp Lys Ile
                  80                  85                  90

 Ser Glu Glu Glu Asp Leu His Leu Gly Thr Ser Phe Ser Ala Glu
                  95                 100                 105

 Thr Asn Arg Arg Asp Glu Asp Ala Asp Met Met Lys Tyr Ile Glu
                 110                 115                 120

 Thr Glu Leu Lys Lys Arg Lys Gly Ile Val Glu His Glu Glu Gln
                 125                 130                 135

 Lys Val Lys Pro Lys Asn Ala Glu Asp Cys Leu Tyr Glu Leu Pro
                 140                 145                 150

 Glu Asn Ile Arg Val Ser Ser Ala Lys Lys Thr Glu Glu Met Leu
                 155                 160                 165

 Ser Asn Gln Met Leu Ser Gly Ile Pro Glu Val Asp Leu Gly Ile
                 170                 175                 180

 Asp Ala Lys Ile Lys Asn Ile Ile Ser Thr Glu Asp Ala Lys Ala
                 185                 190                 195

 Arg Leu Leu Ala Glu Gln Gln Asn Lys Lys Lys Asp Ser Glu Thr
                 200                 205                 210

 Ser Phe Val Pro Thr Asn Met Ala Val Asn Tyr Val Gln His Asn
                 215                 220                 225

 Arg Phe Tyr His Glu Glu Leu Asn Ala Pro Ile Arg Arg Asn Lys
                 230                 235                 240

 Glu Glu Pro Lys Ala Arg Pro Leu Arg Val Gly Asp Thr Glu Lys
                 245                 250                 255

 Pro Glu Pro Glu Arg Ser Pro Pro Asn Arg Lys Arg Pro Ala Asn
                 260                 265                 270

 Glu Lys Ala Thr Asp Asp Tyr His Tyr Glu Lys Phe Lys Lys Met
                 275                 280                 285

 Asn Arg Arg Tyr


<210> 6249
<211> 3432
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 2741
<223> Unknown base

<400> 6249
 ctcgtcatgc gcaatgtggc gctgcggcgg gcggcagggc ctgtgtgtgc 50

 tgaggcggct gagcggcgga catgcacacc acagagcgtg gcgatggaac 100

 agtaaccggg cttgtgagag ggctctgcag tataaactag gagacaagat 150

 ccatggattc accgtaaacc aggtgacatc tgttcccgag ctgttcctga 200

 ctgcagtgaa gctcacccat gatgacacag gagccaggta tttacacctg 250

 gccagagaag acacgaataa tctgttcagc gtgcagttcc gtaccactcc 300

 catggacagt actggtgttc ctcacattct tgagcatacc gtcctttgtg 350

 ggtctcaaaa atatccgtgc agaaaccctt tcttcaaaat gttgaaccgg 400

 tccctctcca cgttcatgaa cgccttcaca gctagtgatt atactctgta 450

 tccattttcc acacaaaatc ccaaggactt tcagaatctc ctctcggtgt 500

 atttggatgc caccttttcc ccatgtttac gcgagctgga tttctggcag 550

 gaaggatggc ggctggaaca tgagaatccg agcgaccccc agacgccctt 600

 ggtctttaaa ggagtcgtct ttaatgagat gaagggagcg tttacagaca 650

 atgagaggat attctcccag caccttcaga acagacttct tcccgaccac 700

 acgtactcag tggtctccgg gggtgaccca ctgtgcatcc cggagcttac 750

 atgggagcag cttaagcagt ttcatgccac tcactatcac ccaagcaatg 800

 ctaggttctt cacgtacggt aattttccat tagaacagca tctgaaacaa 850

 attcacgagg aagcactgag caaattccag aaaattgaac caagcaccgt 900

 ggtgccagct cagacaccct gggacaagcc tagggaattc cagataacat 950

 gtggcccgga ttcatttgct acagatccct ctaaacaaac aaccgtcagc 1000

 gttagcttcc tcttaccgga catcaccgac acatttgaag ccttcacatt 1050

 aagtcttctg tcttcactct tgacttctgg gcccaattct cccttttaca 1100

 aagccttgat tgaatctggc cttggcacag aattttctcc tgatgttgga 1150

 tataatggct acacgaggga ggcctacttt agtgtcggcc tccaagggat 1200

 tgtggagaaa gacattgaga ccgtcagaag cctcatagac agaacgattg 1250

 atgaagtagt tgagacaagg attgaagatg atcgaattga ggctttactt 1300

 cataaaattg aaatacagat gaaacatcag tctaccagct ttgggctgat 1350

 gctgacatca tacatagctt cttgctggaa ccatgatggg gaccctgtgg 1400

 agctcttgaa gttgggaaat cagttagcta aattcagaca gtgcctgcag 1450

 gaaaatccaa aatttttgca agaaaaagta aaacagtatt ttaagaataa 1500

 ccagcataag ctgactttat cgatgaggcc agatgacaag tatcacgaga 1550

 agcaggcaca ggtggaagcc acgaagctca agcagaaggt cgaggctctg 1600

 tcccccggag acaggcagca gatctacgag aaaggtctag aattacggag 1650

 tcaacaaagc aaacctcaag atgcctcttg tctgccagcg ttgaaagttt 1700

 ccgatattga acccaccata cctgtcacag agttggacgt ggtcctgaca 1750

 gctggagata tccctgttca gtactgcgcc cagcccacca atggcatggt 1800

 gtatttccgg gccttctcca gcctgaacac actccccgag gagctgaggc 1850

 cctatgtgcc cctcttctgc agcatcctca ccaagctggg ctgcggcctt 1900

 cttgactacc gggagcaggc tcagcagata gaattgaaga ccggagggat 1950

 gagtgcttct ccccacgtgc tccccgacga ctcacacatg gacacctacg 2000

 agcaggtagg tgtgcttttc tcctctctct gcctggatcg aaacctgcca 2050

 gacatgatgc agctatggag tgaaatattt aacaacccgt gctttgaaga 2100

 agaggagcac ttcaaggtgc tggtgaagat gaccgcccag gagctcgcca 2150

 atggaattcc tgactctggg cacctgtacg catccatcag ggcaggccgg 2200

 accctcacgc ccgcagggga cctgcaggag accttcagcg ggatggatca 2250

 ggtgcggctg atgaagagga ttgcagaaat gacagatatc aaacccatcc 2300

 tgaggaagct cccgcgtatc aagaaacact tgttaaatgg tgataatatg 2350

 aggtgttcag tgaatgcgac tcctcagcag atgcctcaga cagaaaaagc 2400

 ggtcgaagac ttccttagaa gcatcggtcg gagtaaaaag gaacggaggc 2450

 ctgtgcgccc acacacggtc gagaaacctg tgcccagcag ctctggtgga 2500

 gatgcccacg ttccccatgg ctcccaggtc attaggaagc tggtcatgga 2550

 acccaccttc aagccctggc agatgaagac tcacttcctg atgcccttcc 2600

 cggtgaatta cgtgggtgaa tgcatccgaa ctgtccccta cacggaccca 2650

 gatcatgcca gtcttaaaat ccttgcacgt ttgatgactg ccaaattctt 2700

 gcatacagaa attcgagaaa aaggcggtgc ttatggtgga ngcgcaaaac 2750

 tcagccacaa tgggattttc accctttact cttacaggga cccaaataca 2800

 atagagacgc tccagtcttt tgggaaggct gtcgactggg ctaagtctgg 2850

 aaaattcaca cagcaagaca tcgacgaagc caaactttct gtcttctcaa 2900

 ccgtagatgc tcctgtcgct ccttcagaca aaggaatgga ccacttcttg 2950

 tacggcctct cggatgagat gaagcaggcc cacagagagc agctctttgc 3000

 tgtcagccac gacaagctcc tggccgtgag cgataggtac ctcggcactg 3050

 ggaagagcac acacggcctg gccatcctcg gacccgagaa cccgaaaatt 3100

 gccaaggacc catcctggat catccgatga gcagccgtgg cgctcgactg 3150

 cacaggagcc cgagacaata cacctccaag ctgaatatga aaagtcagaa 3200

 atgctactgc tttttccaag aatattatgt cattgagtgt cgccaaagcc 3250

 cttgactggc gagtcaaaaa ctcagatcta tcttaagagt gaccaggaag 3300

 aggttcattg aaataatcat gcatgaagcg ccaaagatgc accatgtaga 3350

 attttcactt tgtactggca ggctcgtttt acctgattct agaatattta 3400

 agaatctaaa aataaagggc aactctgact ta 3432

<210> 6250
<211> 1038
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 910
<223> unknown amino acid

<220>
<221> Unsure
<222> 2741
<223> Unknown amino acid

<400> 6250
 Met Trp Arg Cys Gly Gly Arg Gln Gly Leu Cys Val Leu Arg Arg
   1               5                  10                  15

 Leu Ser Gly Gly His Ala His His Arg Ala Trp Arg Trp Asn Ser
                  20                  25                  30

 Asn Arg Ala Cys Glu Arg Ala Leu Gln Tyr Lys Leu Gly Asp Lys
                  35                  40                  45

 Ile His Gly Phe Thr Val Asn Gln Val Thr Ser Val Pro Glu Leu
                  50                  55                  60

 Phe Leu Thr Ala Val Lys Leu Thr His Asp Asp Thr Gly Ala Arg
                  65                  70                  75

 Tyr Leu His Leu Ala Arg Glu Asp Thr Asn Asn Leu Phe Ser Val
                  80                  85                  90

 Gln Phe Arg Thr Thr Pro Met Asp Ser Thr Gly Val Pro His Ile
                  95                 100                 105

 Leu Glu His Thr Val Leu Cys Gly Ser Gln Lys Tyr Pro Cys Arg
                 110                 115                 120

 Asn Pro Phe Phe Lys Met Leu Asn Arg Ser Leu Ser Thr Phe Met
                 125                 130                 135

 Asn Ala Phe Thr Ala Ser Asp Tyr Thr Leu Tyr Pro Phe Ser Thr
                 140                 145                 150

 Gln Asn Pro Lys Asp Phe Gln Asn Leu Leu Ser Val Tyr Leu Asp
                 155                 160                 165

 Ala Thr Phe Ser Pro Cys Leu Arg Glu Leu Asp Phe Trp Gln Glu
                 170                 175                 180

 Gly Trp Arg Leu Glu His Glu Asn Pro Ser Asp Pro Gln Thr Pro
                 185                 190                 195

 Leu Val Phe Lys Gly Val Val Phe Asn Glu Met Lys Gly Ala Phe
                 200                 205                 210

 Thr Asp Asn Glu Arg Ile Phe Ser Gln His Leu Gln Asn Arg Leu
                 215                 220                 225

 Leu Pro Asp His Thr Tyr Ser Val Val Ser Gly Gly Asp Pro Leu
                 230                 235                 240

 Cys Ile Pro Glu Leu Thr Trp Glu Gln Leu Lys Gln Phe His Ala
                 245                 250                 255

 Thr His Tyr His Pro Ser Asn Ala Arg Phe Phe Thr Tyr Gly Asn
                 260                 265                 270

 Phe Pro Leu Glu Gln His Leu Lys Gln Ile His Glu Glu Ala Leu
                 275                 280                 285

 Ser Lys Phe Gln Lys Ile Glu Pro Ser Thr Val Val Pro Ala Gln
                 290                 295                 300

 Thr Pro Trp Asp Lys Pro Arg Glu Phe Gln Ile Thr Cys Gly Pro
                 305                 310                 315

 Asp Ser Phe Ala Thr Asp Pro Ser Lys Gln Thr Thr Val Ser Val
                 320                 325                 330

 Ser Phe Leu Leu Pro Asp Ile Thr Asp Thr Phe Glu Ala Phe Thr
                 335                 340                 345

 Leu Ser Leu Leu Ser Ser Leu Leu Thr Ser Gly Pro Asn Ser Pro
                 350                 355                 360

 Phe Tyr Lys Ala Leu Ile Glu Ser Gly Leu Gly Thr Glu Phe Ser
                 365                 370                 375

 Pro Asp Val Gly Tyr Asn Gly Tyr Thr Arg Glu Ala Tyr Phe Ser
                 380                 385                 390

 Val Gly Leu Gln Gly Ile Val Glu Lys Asp Ile Glu Thr Val Arg
                 395                 400                 405

 Ser Leu Ile Asp Arg Thr Ile Asp Glu Val Val Glu Thr Arg Ile
                 410                 415                 420

 Glu Asp Asp Arg Ile Glu Ala Leu Leu His Lys Ile Glu Ile Gln
                 425                 430                 435

 Met Lys His Gln Ser Thr Ser Phe Gly Leu Met Leu Thr Ser Tyr
                 440                 445                 450

 Ile Ala Ser Cys Trp Asn His Asp Gly Asp Pro Val Glu Leu Leu
                 455                 460                 465

 Lys Leu Gly Asn Gln Leu Ala Lys Phe Arg Gln Cys Leu Gln Glu
                 470                 475                 480

 Asn Pro Lys Phe Leu Gln Glu Lys Val Lys Gln Tyr Phe Lys Asn
                 485                 490                 495

 Asn Gln His Lys Leu Thr Leu Ser Met Arg Pro Asp Asp Lys Tyr
                 500                 505                 510

 His Glu Lys Gln Ala Gln Val Glu Ala Thr Lys Leu Lys Gln Lys
                 515                 520                 525

 Val Glu Ala Leu Ser Pro Gly Asp Arg Gln Gln Ile Tyr Glu Lys
                 530                 535                 540

 Gly Leu Glu Leu Arg Ser Gln Gln Ser Lys Pro Gln Asp Ala Ser
                 545                 550                 555

 Cys Leu Pro Ala Leu Lys Val Ser Asp Ile Glu Pro Thr Ile Pro
                 560                 565                 570

 Val Thr Glu Leu Asp Val Val Leu Thr Ala Gly Asp Ile Pro Val
                 575                 580                 585

 Gln Tyr Cys Ala Gln Pro Thr Asn Gly Met Val Tyr Phe Arg Ala
                 590                 595                 600

 Phe Ser Ser Leu Asn Thr Leu Pro Glu Glu Leu Arg Pro Tyr Val
                 605                 610                 615

 Pro Leu Phe Cys Ser Ile Leu Thr Lys Leu Gly Cys Gly Leu Leu
                 620                 625                 630

 Asp Tyr Arg Glu Gln Ala Gln Gln Ile Glu Leu Lys Thr Gly Gly
                 635                 640                 645

 Met Ser Ala Ser Pro His Val Leu Pro Asp Asp Ser His Met Asp
                 650                 655                 660

 Thr Tyr Glu Gln Val Gly Val Leu Phe Ser Ser Leu Cys Leu Asp
                 665                 670                 675

 Arg Asn Leu Pro Asp Met Met Gln Leu Trp Ser Glu Ile Phe Asn
                 680                 685                 690

 Asn Pro Cys Phe Glu Glu Glu Glu His Phe Lys Val Leu Val Lys
                 695                 700                 705

 Met Thr Ala Gln Glu Leu Ala Asn Gly Ile Pro Asp Ser Gly His
                 710                 715                 720

 Leu Tyr Ala Ser Ile Arg Ala Gly Arg Thr Leu Thr Pro Ala Gly
                 725                 730                 735

 Asp Leu Gln Glu Thr Phe Ser Gly Met Asp Gln Val Arg Leu Met
                 740                 745                 750

 Lys Arg Ile Ala Glu Met Thr Asp Ile Lys Pro Ile Leu Arg Lys
                 755                 760                 765

 Leu Pro Arg Ile Lys Lys His Leu Leu Asn Gly Asp Asn Met Arg
                 770                 775                 780

 Cys Ser Val Asn Ala Thr Pro Gln Gln Met Pro Gln Thr Glu Lys
                 785                 790                 795

 Ala Val Glu Asp Phe Leu Arg Ser Ile Gly Arg Ser Lys Lys Glu
                 800                 805                 810

 Arg Arg Pro Val Arg Pro His Thr Val Glu Lys Pro Val Pro Ser
                 815                 820                 825

 Ser Ser Gly Gly Asp Ala His Val Pro His Gly Ser Gln Val Ile
                 830                 835                 840

 Arg Lys Leu Val Met Glu Pro Thr Phe Lys Pro Trp Gln Met Lys
                 845                 850                 855

 Thr His Phe Leu Met Pro Phe Pro Val Asn Tyr Val Gly Glu Cys
                 860                 865                 870

 Ile Arg Thr Val Pro Tyr Thr Asp Pro Asp His Ala Ser Leu Lys
                 875                 880                 885

 Ile Leu Ala Arg Leu Met Thr Ala Lys Phe Leu His Thr Glu Ile
                 890                 895                 900

 Arg Glu Lys Gly Gly Ala Tyr Gly Gly Xaa Ala Lys Leu Ser His
                 905                 910                 915

 Asn Gly Ile Phe Thr Leu Tyr Ser Tyr Arg Asp Pro Asn Thr Ile
                 920                 925                 930

 Glu Thr Leu Gln Ser Phe Gly Lys Ala Val Asp Trp Ala Lys Ser
                 935                 940                 945

 Gly Lys Phe Thr Gln Gln Asp Ile Asp Glu Ala Lys Leu Ser Val
                 950                 955                 960

 Phe Ser Thr Val Asp Ala Pro Val Ala Pro Ser Asp Lys Gly Met
                 965                 970                 975

 Asp His Phe Leu Tyr Gly Leu Ser Asp Glu Met Lys Gln Ala His
                 980                 985                 990

 Arg Glu Gln Leu Phe Ala Val Ser His Asp Lys Leu Leu Ala Val
                 995                1000                1005

 Ser Asp Arg Tyr Leu Gly Thr Gly Lys Ser Thr His Gly Leu Ala
                1010                1015                1020

 Ile Leu Gly Pro Glu Asn Pro Lys Ile Ala Lys Asp Pro Ser Trp
                1025                1030                1035

 Ile Ile Arg


<210> 6251
<211> 3159
<212> DNA
<213> Homo sapien

<400> 6251
 atggctggga tggacagtgg caacctgaag accgcgaggc tgtggcggga 50

 cgccgccctg cgtgccagga agctgcggag caacctgcgc cagctcacgc 100

 tcaccgccgc cggggcctgc cccggggccg gggccgacgc gctcgagtcc 150

 cccgcctccc cccagctcgt gctgccggcc aacctcgggg acattgaggc 200

 actgaacctg gggaacaacg gcctggagga ggtacccgag gggctggggt 250

 cggcgctggg cagcctgcgc gtcctggtcc tgcgcaggaa ccgcttcgcc 300

 cggctgcccc cggcggtggc cgagctcggc caccacctca ccgagctgga 350

 cgtgagccac aaccggctga ccgccctggg cgcggaggtg gtgagtgctc 400

 tgagggagct gcggaagctc aacctcagcc acaaccagct gcccgccctg 450

 cccgcccagc tgggcgctct cgctcacctg gaggagctgg atgtcagctt 500

 taaccggctg gcgcacctgc ctgactccct ctcctgcctc tcccgcctgc 550

 gcaccctgga cgtggatcac aaccagctca ctgccttccc ccggcagctg 600

 ctgcagctgg tggccctgga ggagctggac gtgtccagca accggctgcg 650

 gggcctgcct gaggatatca gtgccctgcg tgccctcaag atcctctggc 700

 tgagtggggc cgagcttggc acgctgcccg ccggcttctg cgagctggcc 750

 agtttggaga gcctcatgct agacaacaac gggctgcagg ctctgcccgc 800

 ccagttcagc tgcctgcagc ggctcaaaat gctcaacctg tcctccaacc 850

 tcttcgagga gttccctgcc gcgctgctgc ccctggctgg tctggaggag 900

 ctctacctta gtcgcaacca gctcacctcg gtgccatccc ttatctcggg 950

 cctgggccgg cttctcacct tgtggctgga taataaccgc atccgctacc 1000

 tgccggactc catcgtggag ctgaccggcc tggaggagct cgtgctgcag 1050

 gggaaccaga tcgcggtgct gcccgaccac tttggccagc tctcccgggt 1100

 gggtttgtgg aagatcaaag acaacccact gatccagccc ccctacgagg 1150

 tctgcatgaa ggggatcccc tacatcgcag cctaccagaa ggaactggct 1200

 cattcccagc cggcggtgca gccccggctc aagctgctcc tgatggggca 1250

 taaggctgca ggaaagactt tgctgcgcca ctgcctcacc gaggagagag 1300

 tggagggatg cccaggagga ggggacaagg agaagtgcta cccaccgtca 1350

 cctccccctg tgagcaaggg catcgaggtg accagctgga cggccgatgc 1400

 ctcccggggc ctgcggttca tcgtgtatga cttagctggg gatgaaagtt 1450

 atgaggtgat ccagcccttc ttcctgtccc caggggccct atacgtgctg 1500

 gtggtcaact tggccaccta tgagcctcgc cactttccta ccaccgtggg 1550

 ctccttcttg catcgggtcg gggcgagagt gcccaacgcg gtggtgtgca 1600

 tcgtgggcac ccacgcagac ctgtgcggag agcgtgagct ggaggagaaa 1650

 tgtctggaca ttcaccgcca gatcgccctg caggagaagc acgacgcgga 1700

 gggactgagc cgcttggcca aggtggtgga cgaggcactg gcccgggact 1750

 tcgagctgcg ctctgccagc ccccacgcag cctactatgg cgtttcggac 1800

 aagaaccttc gacggcgcaa ggcccatttt caatacctgc tcaaccaccg 1850

 gctgcagatc ctctcccccg tgttgcctgt tagctgcagg gacccgcgcc 1900

 acttacgacg ccttcgggac aagttgctgt cagttgctga gcaccgagag 1950

 atcttcccca acttacacag agtactgcct cgatcctggc aggtgctgga 2000

 ggaactgcat ttccagccac ctcaggccca gcgactgtgg ctaagctggt 2050

 gggactcggc gcgcttgggc ctgcaggcgg gtctgaccga ggaccgactg 2100

 cagagtgccc tctcctacct gcatgagagc ggcaagctac tctactttga 2150

 ggacagtccg gctctcaagg agcacgtctt ccacaacctc acccgcctca 2200

 tcgacatcct caatgtcttc ttccagaggg atccctcttt gctgctgcat 2250

 aagctgctcc tagggaccag tggagagggc aaggcggagg gggaaagctc 2300

 cccgcccatg gcgcggtcca cccccagcca ggaactgctc cgggccaccc 2350

 agctccatca gtatgtggag ggctttctgt tgcatgggct cttgccagct 2400

 catgtcattc ggttgctgct taagcctcat gtccaggccc agcaggactt 2450

 gcagctgttg ctggagctgc tggagaagat gggactctgt tactgcctca 2500

 ataaacccaa gggcaagcct ttgaatgggt ccacagcttg gtacaagttc 2550

 ccatgctatg tgcagaacga ggtgccccat gcagaagcct ggattaatgg 2600

 gaccaaccta gctgggcagt cttttgtggc tgagcagttg cagattgaat 2650

 atagctttcc ttttactttt ccacctgggt tgtttgcacg ctacagtgtc 2700

 cagatcaaca gccatgtggt gcacaggtcg gatggtaaat ttcagatctt 2750

 tgcctataga gggaaagttc ctgtggttgt gagttacaga cctgccaggg 2800

 gagtcctgca gccagacacc ctgtccattg ctagccatgc atcattacca 2850

 aatatatgga ccgcatggca agccataacc cccttggtgg aggaactgaa 2900

 tgtcctactt caggaatggc ctggactgca ctacaccgtg cacattctct 2950

 gttctaagtg ccttaagaga ggatcgccca atccacatgc ttttccaggg 3000

 gagttgctga gtcagcccag accggaagga gtggcagaga tcatttgccc 3050

 caagaacggc agcgagcgag taaatgttgc cttggtttac ccacccacgc 3100

 cgactgtgat cagcccctgt tccaagaaga atgttggtga aaagcacaga 3150

 aaccagtga 3159

<210> 6252
<211> 1052
<212> PRT
<213> Homo sapien

<400> 6252
 Met Ala Gly Met Asp Ser Gly Asn Leu Lys Thr Ala Arg Leu Trp
   1               5                  10                  15

 Arg Asp Ala Ala Leu Arg Ala Arg Lys Leu Arg Ser Asn Leu Arg
                  20                  25                  30

 Gln Leu Thr Leu Thr Ala Ala Gly Ala Cys Pro Gly Ala Gly Ala
                  35                  40                  45

 Asp Ala Leu Glu Ser Pro Ala Ser Pro Gln Leu Val Leu Pro Ala
                  50                  55                  60

 Asn Leu Gly Asp Ile Glu Ala Leu Asn Leu Gly Asn Asn Gly Leu
                  65                  70                  75

 Glu Glu Val Pro Glu Gly Leu Gly Ser Ala Leu Gly Ser Leu Arg
                  80                  85                  90

 Val Leu Val Leu Arg Arg Asn Arg Phe Ala Arg Leu Pro Pro Ala
                  95                 100                 105

 Val Ala Glu Leu Gly His His Leu Thr Glu Leu Asp Val Ser His
                 110                 115                 120

 Asn Arg Leu Thr Ala Leu Gly Ala Glu Val Val Ser Ala Leu Arg
                 125                 130                 135

 Glu Leu Arg Lys Leu Asn Leu Ser His Asn Gln Leu Pro Ala Leu
                 140                 145                 150

 Pro Ala Gln Leu Gly Ala Leu Ala His Leu Glu Glu Leu Asp Val
                 155                 160                 165

 Ser Phe Asn Arg Leu Ala His Leu Pro Asp Ser Leu Ser Cys Leu
                 170                 175                 180

 Ser Arg Leu Arg Thr Leu Asp Val Asp His Asn Gln Leu Thr Ala
                 185                 190                 195

 Phe Pro Arg Gln Leu Leu Gln Leu Val Ala Leu Glu Glu Leu Asp
                 200                 205                 210

 Val Ser Ser Asn Arg Leu Arg Gly Leu Pro Glu Asp Ile Ser Ala
                 215                 220                 225

 Leu Arg Ala Leu Lys Ile Leu Trp Leu Ser Gly Ala Glu Leu Gly
                 230                 235                 240

 Thr Leu Pro Ala Gly Phe Cys Glu Leu Ala Ser Leu Glu Ser Leu
                 245                 250                 255

 Met Leu Asp Asn Asn Gly Leu Gln Ala Leu Pro Ala Gln Phe Ser
                 260                 265                 270

 Cys Leu Gln Arg Leu Lys Met Leu Asn Leu Ser Ser Asn Leu Phe
                 275                 280                 285

 Glu Glu Phe Pro Ala Ala Leu Leu Pro Leu Ala Gly Leu Glu Glu
                 290                 295                 300

 Leu Tyr Leu Ser Arg Asn Gln Leu Thr Ser Val Pro Ser Leu Ile
                 305                 310                 315

 Ser Gly Leu Gly Arg Leu Leu Thr Leu Trp Leu Asp Asn Asn Arg
                 320                 325                 330

 Ile Arg Tyr Leu Pro Asp Ser Ile Val Glu Leu Thr Gly Leu Glu
                 335                 340                 345

 Glu Leu Val Leu Gln Gly Asn Gln Ile Ala Val Leu Pro Asp His
                 350                 355                 360

 Phe Gly Gln Leu Ser Arg Val Gly Leu Trp Lys Ile Lys Asp Asn
                 365                 370                 375

 Pro Leu Ile Gln Pro Pro Tyr Glu Val Cys Met Lys Gly Ile Pro
                 380                 385                 390

 Tyr Ile Ala Ala Tyr Gln Lys Glu Leu Ala His Ser Gln Pro Ala
                 395                 400                 405

 Val Gln Pro Arg Leu Lys Leu Leu Leu Met Gly His Lys Ala Ala
                 410                 415                 420

 Gly Lys Thr Leu Leu Arg His Cys Leu Thr Glu Glu Arg Val Glu
                 425                 430                 435

 Gly Cys Pro Gly Gly Gly Asp Lys Glu Lys Cys Tyr Pro Pro Ser
                 440                 445                 450

 Pro Pro Pro Val Ser Lys Gly Ile Glu Val Thr Ser Trp Thr Ala
                 455                 460                 465

 Asp Ala Ser Arg Gly Leu Arg Phe Ile Val Tyr Asp Leu Ala Gly
                 470                 475                 480

 Asp Glu Ser Tyr Glu Val Ile Gln Pro Phe Phe Leu Ser Pro Gly
                 485                 490                 495

 Ala Leu Tyr Val Leu Val Val Asn Leu Ala Thr Tyr Glu Pro Arg
                 500                 505                 510

 His Phe Pro Thr Thr Val Gly Ser Phe Leu His Arg Val Gly Ala
                 515                 520                 525

 Arg Val Pro Asn Ala Val Val Cys Ile Val Gly Thr His Ala Asp
                 530                 535                 540

 Leu Cys Gly Glu Arg Glu Leu Glu Glu Lys Cys Leu Asp Ile His
                 545                 550                 555

 Arg Gln Ile Ala Leu Gln Glu Lys His Asp Ala Glu Gly Leu Ser
                 560                 565                 570

 Arg Leu Ala Lys Val Val Asp Glu Ala Leu Ala Arg Asp Phe Glu
                 575                 580                 585

 Leu Arg Ser Ala Ser Pro His Ala Ala Tyr Tyr Gly Val Ser Asp
                 590                 595                 600

 Lys Asn Leu Arg Arg Arg Lys Ala His Phe Gln Tyr Leu Leu Asn
                 605                 610                 615

 His Arg Leu Gln Ile Leu Ser Pro Val Leu Pro Val Ser Cys Arg
                 620                 625                 630

 Asp Pro Arg His Leu Arg Arg Leu Arg Asp Lys Leu Leu Ser Val
                 635                 640                 645

 Ala Glu His Arg Glu Ile Phe Pro Asn Leu His Arg Val Leu Pro
                 650                 655                 660

 Arg Ser Trp Gln Val Leu Glu Glu Leu His Phe Gln Pro Pro Gln
                 665                 670                 675

 Ala Gln Arg Leu Trp Leu Ser Trp Trp Asp Ser Ala Arg Leu Gly
                 680                 685                 690

 Leu Gln Ala Gly Leu Thr Glu Asp Arg Leu Gln Ser Ala Leu Ser
                 695                 700                 705

 Tyr Leu His Glu Ser Gly Lys Leu Leu Tyr Phe Glu Asp Ser Pro
                 710                 715                 720

 Ala Leu Lys Glu His Val Phe His Asn Leu Thr Arg Leu Ile Asp
                 725                 730                 735

 Ile Leu Asn Val Phe Phe Gln Arg Asp Pro Ser Leu Leu Leu His
                 740                 745                 750

 Lys Leu Leu Leu Gly Thr Ser Gly Glu Gly Lys Ala Glu Gly Glu
                 755                 760                 765

 Ser Ser Pro Pro Met Ala Arg Ser Thr Pro Ser Gln Glu Leu Leu
                 770                 775                 780

 Arg Ala Thr Gln Leu His Gln Tyr Val Glu Gly Phe Leu Leu His
                 785                 790                 795

 Gly Leu Leu Pro Ala His Val Ile Arg Leu Leu Leu Lys Pro His
                 800                 805                 810

 Val Gln Ala Gln Gln Asp Leu Gln Leu Leu Leu Glu Leu Leu Glu
                 815                 820                 825

 Lys Met Gly Leu Cys Tyr Cys Leu Asn Lys Pro Lys Gly Lys Pro
                 830                 835                 840

 Leu Asn Gly Ser Thr Ala Trp Tyr Lys Phe Pro Cys Tyr Val Gln
                 845                 850                 855

 Asn Glu Val Pro His Ala Glu Ala Trp Ile Asn Gly Thr Asn Leu
                 860                 865                 870

 Ala Gly Gln Ser Phe Val Ala Glu Gln Leu Gln Ile Glu Tyr Ser
                 875                 880                 885

 Phe Pro Phe Thr Phe Pro Pro Gly Leu Phe Ala Arg Tyr Ser Val
                 890                 895                 900

 Gln Ile Asn Ser His Val Val His Arg Ser Asp Gly Lys Phe Gln
                 905                 910                 915

 Ile Phe Ala Tyr Arg Gly Lys Val Pro Val Val Val Ser Tyr Arg
                 920                 925                 930

 Pro Ala Arg Gly Val Leu Gln Pro Asp Thr Leu Ser Ile Ala Ser
                 935                 940                 945

 His Ala Ser Leu Pro Asn Ile Trp Thr Ala Trp Gln Ala Ile Thr
                 950                 955                 960

 Pro Leu Val Glu Glu Leu Asn Val Leu Leu Gln Glu Trp Pro Gly
                 965                 970                 975

 Leu His Tyr Thr Val His Ile Leu Cys Ser Lys Cys Leu Lys Arg
                 980                 985                 990

 Gly Ser Pro Asn Pro His Ala Phe Pro Gly Glu Leu Leu Ser Gln
                 995                1000                1005

 Pro Arg Pro Glu Gly Val Ala Glu Ile Ile Cys Pro Lys Asn Gly
                1010                1015                1020

 Ser Glu Arg Val Asn Val Ala Leu Val Tyr Pro Pro Thr Pro Thr
                1025                1030                1035

 Val Ile Ser Pro Cys Ser Lys Lys Asn Val Gly Glu Lys His Arg
                1040                1045                1050

 Asn Gln


<210> 6253
<211> 2058
<212> DNA
<213> Homo sapien

<400> 6253
 cggtgctagc gacacgggag tggcaaacgc atcctcttgc cgttcccggt 50

 gtttgggcct tgcctgtgac ggtgggaaaa gaaaatggcc ttgctgtgct 100

 acaaccgggg ctgcggtcag cgcttcgatc ctgagaccaa ttccgacgat 150

 gcttgcacat accacccagg tgttccggtc tttcacgatg cattaaaggg 200

 ttggtcttgc tgtaagagaa gaacaactga tttttctgat ttcttaagca 250

 ttgtaggctg tacaaaaggt agacataata gtgagaagcc acctgagcca 300

 gtcaaacctg aagtcaagac tactgagaag aaggagctat gtgaattaaa 350

 acccaaattt caggaacaca tcattcaagc ccctaagcca gtagaagcaa 400

 taaaaagacc aagcccagat gaaccaatga caaatttgga attaaaaata 450

 tctgcctccc taaaacaagc acttgataaa cttaaactgt catcagggaa 500

 tgaagaaaat aagaaagaag aagacaatga tgaaattaag attgggacct 550

 catgtaagaa tggagggtgt tcaaagacat accagggtct agagagtcta 600

 gaagaagtct gtgtatatca ttctggagta cctattttcc atgaggggat 650

 gaaatactgg agctgttgta gaagaaaaac ttctgatttt aatacattct 700

 tagcccaaga gggctgtaca aaagggaaac acatgtggac taaaaaagat 750

 gctgggaaaa aagttgttcc atgtagacat gacttgcatc agactggagg 800

 tgaagttacc atttcagtat atgctaaaaa ctcacttcca gaacttagcc 850

 gagtagaagc aaatagcaca ttgttaaatg tcattattgt atttgaagga 900

 gagaaggaat ttgatcaaaa tgtgaaatta tggggtgtga ttgatgtaaa 950

 gcgaagttat gtaactatga ctgcaacaaa gattgaaatc actatgagaa 1000

 aagctgaacc gatgcagtgg gcaagccttg aactgcctgc agctaaaaag 1050

 caggaaaaac aaaaagatga cacaacagat tgagtgggag atggaaggaa 1100

 ggctattaca ttatttccga atttttaata ctgtgtgaag tggtggcttg 1150

 ctgctgtaat cttttgtttt gttgttgtgt tactgaatgt ggcatttcag 1200

 ggttaacatt aggttcttaa aagccaaagt cagtttgtct ttttgtgcct 1250

 ctcatctttc ttttgtgtta tgtaagattg attattcatt tctccctact 1300

 ggtaggaacc atagttgtgt cctatacttg aagaggctgg aaagtagccc 1350

 ataaccataa ttgcagtatt tctttgtatt tctctgttaa gcaaagaaat 1400

 attaaggaac atttttttta tgtttttgta ttattccata attagtaaag 1450

 caagatgaaa tgtcaaattt taatcagttt tttcatggat ttgtgttctt 1500

 acagtacttg aaaatattta aggaagagat gaagctctgc agttttttct 1550

 atgtgggatg attacttttt taaggaggat taattctgag gtagtatagt 1600

 aactaaaggg gaatatatga attgtttaac aaattagaat ttgtttacaa 1650

 ctacttgaat ttttaaatta tgtcaaaact tacattactt gccaagcagt 1700

 atgatgttat aggaaacata aataagatta cagaggtatc aatttggtta 1750

 aaattcacca ttttataaga ctaagcaata atcttaacaa cctctttcct 1800

 gaatatttaa atgtgtttgt atggtgttat gactaattgt tactgattta 1850

 gagactaagc cctcttaaaa cctttagtta aatataaaaa gaaattatat 1900

 atatcttgcc tccctgatgg aaaactatat aaaattgtag acttaaaagg 1950

 tttgtggaaa tacattagga tatcagaaaa ctaaatatat ggagttgctt 2000

 tatgactatt acatgttaaa taaaaatagc ttaattgtta aaaaaaaaaa 2050

 aaaaaaaa 2058

<210> 6254
<211> 332
<212> PRT
<213> Homo sapien

<400> 6254
 Met Ala Leu Leu Cys Tyr Asn Arg Gly Cys Gly Gln Arg Phe Asp
   1               5                  10                  15

 Pro Glu Thr Asn Ser Asp Asp Ala Cys Thr Tyr His Pro Gly Val
                  20                  25                  30

 Pro Val Phe His Asp Ala Leu Lys Gly Trp Ser Cys Cys Lys Arg
                  35                  40                  45

 Arg Thr Thr Asp Phe Ser Asp Phe Leu Ser Ile Val Gly Cys Thr
                  50                  55                  60

 Lys Gly Arg His Asn Ser Glu Lys Pro Pro Glu Pro Val Lys Pro
                  65                  70                  75

 Glu Val Lys Thr Thr Glu Lys Lys Glu Leu Cys Glu Leu Lys Pro
                  80                  85                  90

 Lys Phe Gln Glu His Ile Ile Gln Ala Pro Lys Pro Val Glu Ala
                  95                 100                 105

 Ile Lys Arg Pro Ser Pro Asp Glu Pro Met Thr Asn Leu Glu Leu
                 110                 115                 120

 Lys Ile Ser Ala Ser Leu Lys Gln Ala Leu Asp Lys Leu Lys Leu
                 125                 130                 135

 Ser Ser Gly Asn Glu Glu Asn Lys Lys Glu Glu Asp Asn Asp Glu
                 140                 145                 150

 Ile Lys Ile Gly Thr Ser Cys Lys Asn Gly Gly Cys Ser Lys Thr
                 155                 160                 165

 Tyr Gln Gly Leu Glu Ser Leu Glu Glu Val Cys Val Tyr His Ser
                 170                 175                 180

 Gly Val Pro Ile Phe His Glu Gly Met Lys Tyr Trp Ser Cys Cys
                 185                 190                 195

 Arg Arg Lys Thr Ser Asp Phe Asn Thr Phe Leu Ala Gln Glu Gly
                 200                 205                 210

 Cys Thr Lys Gly Lys His Met Trp Thr Lys Lys Asp Ala Gly Lys
                 215                 220                 225

 Lys Val Val Pro Cys Arg His Asp Leu His Gln Thr Gly Gly Glu
                 230                 235                 240

 Val Thr Ile Ser Val Tyr Ala Lys Asn Ser Leu Pro Glu Leu Ser
                 245                 250                 255

 Arg Val Glu Ala Asn Ser Thr Leu Leu Asn Val Ile Ile Val Phe
                 260                 265                 270

 Glu Gly Glu Lys Glu Phe Asp Gln Asn Val Lys Leu Trp Gly Val
                 275                 280                 285

 Ile Asp Val Lys Arg Ser Tyr Val Thr Met Thr Ala Thr Lys Ile
                 290                 295                 300

 Glu Ile Thr Met Arg Lys Ala Glu Pro Met Gln Trp Ala Ser Leu
                 305                 310                 315

 Glu Leu Pro Ala Ala Lys Lys Gln Glu Lys Gln Lys Asp Asp Thr
                 320                 325                 330

 Thr Asp


<210> 6255
<211> 5338
<212> DNA
<213> Homo sapien

<400> 6255
 ggccgcgagt gcatcttcca cgaacctaat tcatctctcc agcaaaggac 50

 acatctctcc agcaaaggac acctctctcc agcaaaggac acctgcagag 100

 atgtccccag tccttcactt ctatgttcgt ccctctggcc atgagggggc 150

 agcctctgga cacactcgga ggaaactgca agggaaactg ccagagctgc 200

 agggcgtcga gactgaactg tgctacaacg tgaactggac agctgaggcc 250

 ctccccagtg ctgaggagac aaagaagctg atgtggctgt ttggttgccc 300

 cttactgctg gatgatgttg ctcgggagtc ctggctcctt cctggctcca 350

 atgacctgct gctggaggtc gggcccaggc tgaacttctc caccccaaca 400

 tccaccaaca tcgtgtcagt gtgccgcgcc actgggctgg ggcctgtgga 450

 tcgtgtggag accacccggc gctaccggct ctcgtttgcc caccccccgt 500

 cagctgaggt ggaagccatt gctctggcta ccctgcacga ccggatgaca 550

 gagcagcact tcccccatcc catccagagt ttctcccctg agagcatgcc 600

 ggaacccctc aatggcccta tcaatatact gggtgagggc cggcttgcgc 650

 tggagaaggc caaccaggag cttggtctgg ctttagactc ttgggaccta 700

 gacttctaca ccaagcgctt ccaggagcta cagcggaacc cgagcactgt 750

 ggaggccttt gacttggcgc agtccaatag cgagcacagc cgacactggt 800

 tcttcaaggg ccagctccac gtggatgggc agaagctggt gcactcactg 850

 tttgagtcca tcatgagcac ccaggaatcc tcgaacccca acaacgtcct 900

 caaattctgt gataacagca gtgcaatcca gggaaaggaa gtccgattcc 950

 tacggcctga ggaccccaca cggccaagcc gcttccagca acagcaaggg 1000

 ctgagacatg ttgtcttcac agcagagact cacaactttc ccacaggagt 1050

 atgccccttt agtggtgcaa ccactggcac agggggccgg attcgagatg 1100

 tccagtgcac aggccgcggg gcccacgtgg tggctggcac tgccggctat 1150

 tgctttggaa atctgcatat tccaggttac aatctgccct gggaggatct 1200

 aagcttccag tatcctggga attttgcccg gcccctggag gttgccattg 1250

 aagccagtaa tggagcttct gactatggca acaagtttgg ggaaccagtg 1300

 ctggctggct tcgcccgctc cttgggcctc cagctcccag acggccagcg 1350

 gcgtgagtgg atcaagccca tcatgtttag tgggggcatt gggtccatgg 1400

 aagctgacca cataagcaag gaggccccag agccaggcat ggaagttgta 1450

 aaggttggag gtcccgtcta caggattgga gttggaggtg gagctgcttc 1500

 atctgtgcag gtgcagggag ataacaccag tgacctggac tttggggctg 1550

 tgcagcgagg agacccggag atggaacaga agatgaaccg tgtgatcagg 1600

 gcttgtgtgg aggcccccaa gggaaacccc atctgcagcc ttcatgatca 1650

 gggcgctggt ggcaatggca atgtcctaaa agagctgagt gacccagctg 1700

 gagccatcat ttacaccagc cgcttccagc ttggggaccc aaccctgaat 1750

 gccctggaaa tctggggggc tgagtaccag gaatcaaatg ctcttctgct 1800

 gaggtccccc aaccgggact tcctgactca tgtcagtgcc cgtgaacgtt 1850

 gcccggcttg cttcgtgggc accatcactg gagaccggag aatagtgctg 1900

 gtggacgatc gggagtgtcc tgtcagaaga aatggccagg gggatgcccc 1950

 cccgacaccc ccgccaaccc ctgtggacct ggagctcgaa tgggtgctgg 2000

 gcaagatgcc tcggaaggag ttcttcctgc agaggaagcc ccccatgctg 2050

 cagcctctgg ccttgccccc agggctgagc gtgcaccagg ctctggagag 2100

 ggttctgagg ctgcccgccg tggccagcaa gcgctacctc accaataagg 2150

 tggaccgctc cgtgggaggc ctggtggccc agcagcagtg cgtggggccc 2200

 ctgcaaactc ctctggcaga tgtagcggtt gtggcactga gccatgagga 2250

 gctcataggg gctgccacag ccttgggaga acagccagtc aagagcctgc 2300

 tggacccaaa agtcgccgcc cggctggccg tggccgaagc cctcaccaac 2350

 ctggtgtttg ctctggtcac tgacctccgg gatgtgaagt gtagcgggaa 2400

 ctggatgtgg gcagccaagc tcccagggga gggcgcagct ttggcggatg 2450

 cctgtgaggc tatggtggca gtgatggcag ccctgggtgt ggcagtggat 2500

 ggtggcaagg actccctcag catggctgct cgggttggca ctgagaccgt 2550

 gcgggctcct gggtcactgg tcatctcagc ctatgccgtc tgcccagaca 2600

 tcacagccac tgtgacccca gacctcaagc atcctgaagg gagaggccat 2650

 ctgctctatg tggctctgag ccctgggcag caccggctcg ggggcacagc 2700

 tctggcccag tgcttctccc agcttgggga acaccctcca gacctggacc 2750

 ttcctgagaa cttggtgcgg gccttcagca tcactcaggg gctgctgaaa 2800

 gaccgcctcc tctgctcagg ccacgatgtc agtgacggag gcctcgtcac 2850

 atgcctgctg gagatggcct ttgctggaaa ttgcgggcta caggtggatg 2900

 tgcctgtccc cagggttgat gtcctgtctg tgctgttcgc tgaggagcca 2950

 ggcctcgtgc tggaggtgca ggagccagac ctggcccagg tgctgaagcg 3000

 ttaccgggat gctggcctcc attgcctgga gctgggccac acaggcgagg 3050

 ccgggcccca cgccatggtc cgggtgtcag tgaacggggc tgtggttctg 3100

 gaggagcctg ttggggagct gcgagccctc tgggaggaga cgagtttcca 3150

 gctggaccgg ctacaggcag agcctcgctg tgtggcagag gaggaacggg 3200

 gcctgaggga gcggatgggg cccagctatt gcctgccccc cacctttccc 3250

 aaagcctccg tgccccgtga gcctggtggt cccagccccc gagtcgccat 3300

 cttgcgagag gagggcagta atggagaccg ggagatggcc gatgccttcc 3350

 acttagctgg gtttgaggta tgggacgtga ccatgcagga cctctgctct 3400

 ggggcaattg ggctggacac tttccgtggc gtggccttcg tgggcggctt 3450

 cagctatgca gatgtcctgg gctctgccaa agggtgggca gctgctgtga 3500

 cctttcatcc cagggctggg gctgagctga ggcgcttccg gaagcggcca 3550

 gacaccttca gcctgggcgt gtgtaatggc tgtcaactgc tggctctgct 3600

 cggctgggtg ggaggcgacc ccaatgagga tgctgcagag atgggccctg 3650

 actcccagcc agcccggcca ggccttctgc tacgccacaa cctgtctggg 3700

 cgctacgagt ctcgctgggc cagcgtgcgt gtggggcctg ggccagccct 3750

 gatgctgcga gggatggagg gcgccgtgct gcccgtgtgg agtgcgcacg 3800

 gggaaggtta cgtagcattt tcttctccgg aactccaagc tcagattgag 3850

 gccaggggct tggctccact gcactgggct gatgatgacg ggaaccccac 3900

 agagcagtac cctctgaatc ccaatgggtc cccagggggc gtggctggca 3950

 tctgctcctg tgatggccgc cacctggctg tcatgcctca ccctgagcgg 4000

 gccgttaggc cttggcagtg ggcatggcga ccccctccat ttgatactct 4050

 gaccacctcc ccctggctcc agctctctat caatgcccga aactggaccc 4100

 tggaagggag ctgctgactg gccacagggg ctcacctggg ccccatggct 4150

 tttcacctaa gtgggtcctg ccccctcccc catgaccttc aggagcaccc 4200

 catattattt ccaaaaatat cttggacaga caaggaccaa aatgccaaaa 4250

 tctcagcgga ctcgatgatc tgcctgctga tgttccttct gtggctgtgt 4300

 ctattttcag ttctgctcta acatggcatg ccctttctca gcccaggaaa 4350

 cagcatgtgg ttcagagaaa agagcgacaa ggaaaagtta ggactcctga 4400

 ggtccgaaca ggggcttctg ttgcccactt cacaacaccc agtgatcacc 4450

 ggtgtgcaat tgcctccttg gctctgaggg atgttttgcg ctcccttttc 4500

 tcatcattgg ggttagcggg tgcagacaaa ttcagcaata gtatgcagat 4550

 cagcccctca ccacctcatt gttctcatct ggaactgaaa ctttctggat 4600

 ttctcttgaa gtgctacact gcactgaatg taaggaattg ttgcttgtgg 4650

 aagtttctca gcgtttctgg ctgtcttagg gctggcctca gaacccagca 4700

 ttcctgttat ttgcttctaa attagcagct ctcttttttt tttttttttt 4750

 gaggcagtct cactctgtca cccaggctgg agtgcagtgg cgtgatctcg 4800

 gcccactgca acctctgcct cctgggttca agcaattttc ctgcctcagc 4850

 ctcccgagta gctgggagta caggcacaca ccaccacacc cagctaattt 4900

 ttgtattttt agtagagata gggtttcacc gtgtctccca ggctggtctc 4950

 aaactcctaa cctcaagtga ttcgcctgcc tcggcctccc aaagtgctgg 5000

 gattacaggt gggagccact acagctggcc cagcagctct gtttctgata 5050

 gaggtggttg gggctctcat ccctagatcc taacccttta gtatgctgga 5100

 attctactct tcacttactg cattgactgt tgttgattag ttattattgc 5150

 aaagcactgc caccggcctc agggagttta tgtgtaatag aattaaaaat 5200

 aatagctgtg tataacactt agctcaagcc acgcatgtgt gaggcatttg 5250

 gtatgtatct gaattaattc tcactaaaat tcagcaaagg acttgatagc 5300

 ctctccccgc cttttcaata aaggatgaat gaaggttg 5338

<210> 6256
<211> 4152
<212> DNA
<213> Homo sapien

<400> 6256
 cccaggccgg ctctggcctc ctgacccaga cagcgcaggg cgcgagggat 50

 cgcgcggccg agcccgggtc gcgccgctcc cagcatcggg gccgctagcc 100

 aagagttcga ggccttcccg atccggatgt gatgaaaaag agcaacagag 150

 ggagaagtgt ttcaggattg taggagtgga agaggggaaa gagaggcaga 200

 gagggggaag gccccctcgc aggggagccg gctggagtga gctggctgga 250

 aagagggggc ggagtgcgcg gagtcagagc cgccaccgct gccgcagttg 300

 ccgccactgc ggcgtctggg ctgagccgga gggaggcggg aggacgcgca 350

 ggggcggccg ccgccgtcgt caggccaccg gggcgaaaat gcggccgctg 400

 ccggaggctc gctaactttc cggggcggaa gaggaggagg aggaggagga 450

 aggggcttgg agcgactacg gggggatgcg gagaagcagt cagttccctg 500

 cacccagcac ctcacagccc ttcctccgtg cgccctgccg ggcggcgagc 550

 taggcggcag cggcgcggcg cgggctcggc ggagcggccc atgtccggcg 600

 cgggcgaagc cctcgctccc gggcccgtgg ggccgcagcg cgtggccgag 650

 gcgggcggcg gccagctggg ctccacagcc cagggaaaat gtgataaaga 700

 caatactgag aaagatataa ctcaagctac caatagccac ttcacacatg 750

 gagagatgca agaccagtcc atttggggaa atccttcgga tggtgaactc 800

 attagaaccc aacctcagcg cttgcctcag cttcagactt cagcacaggt 850

 gccaagtggt gaggaaatag gcaagataaa gaacggccac acaggtctga 900

 gcaatggaaa tggaattcac cacggggcca aacacggatc cgcagataat 950

 cgcaaacttt cagcacctgt ttctcaaaaa atgcatagaa aaattcagtc 1000

 cagcttgtct gtaaacagcg atatcagtaa gaagagcaaa gtaaatgctg 1050

 tcttttccca aaagacaggc tcttcacctg aagattgttg tgtccactgt 1100

 atcctggctt gcttgttctg cgaattcctg accctttgca acattgtcct 1150

 gggacaagcg tcatgtggca tctgcacctc agaagcctgc tgctgttgct 1200

 gtggtgacga gatgggggat gattgtaact gcccttgtga tatggactgt 1250

 ggcatcatgg atgcctgttg tgaatcatca gactgcttgg aaatctgtat 1300

 ggaatgctgt ggaatttgtt ttccttcata aatatttatc ttttgtttgt 1350

 gttaaaactg gagagtgttt aaaaatttcc ttttgggggg aagaaaagca 1400

 cattgtaaga ttctcatgaa acaacatgga atttgcactg ttaactcatt 1450

 attgtaagta atctctgaaa gcctttttac tttaaccaaa tctacatggt 1500

 ttaatatgtg aaattttaac tactttaact agttttataa atttcttaat 1550

 atgttacaat aacttaggga cattttgaca ccccccttcc caaatgttaa 1600

 atgccttctc ctttttaccg atatttctgt ttcttttaac cgttctcagg 1650

 agcactttgc tccaaatata ttatttttca gtgtgtattt aaacgaggca 1700

 gtttattttg atatgtatct attcatgatt gaaaggaagc agtcttggcc 1750

 aggcacggtg gcttacacct gtaaccctgg cattttggga ggccaaggtg 1800

 ggcagattgc ctgagctcag gagttcgaga ccagccaggg caacatggtg 1850

 aaaccccatc tctactaaaa tacaaaaagt tagctgggct tggcggtgtg 1900

 cgcctgtagt cccagctact caggaggctg aggcaggaga attgcttgaa 1950

 cccgagaggc ggaagttgca gtgagccgag attgtgccac tgaactccaa 2000

 cctgcactcc agcctgggca acagagcgag actccatctc taaataaata 2050

 aataaataaa taaataaata aataaataaa taaataaaca aaccagtctt 2100

 tattttaaaa gaaactttag gaaacaaacc cacataatag ttgggaacca 2150

 gtgttgatct ctctccctta ccttctccac ttgttcaaca gactctgaat 2200

 gccgactgtg tggactctct tcctcagact gtggggacag atacaattcc 2250

 actcctgtcc acaggaacat gagatttagc agactaagga gatctgtaaa 2300

 gaatgaacca taccacaagg catactgaag tgaggattat aagagaaata 2350

 aactcaaaat gctgttggaa tatgcagaga attgctacca gaatattcag 2400

 taaggtttca gggagaatgt ggcatttgag gactctctta gaatgagtga 2450

 ttcacctgct atttaaatga attatttaga tttttgacaa agatttaggt 2500

 ggacacccta aactgtgtgt gcctttaacc agttaaaaga acagtgcctt 2550

 cagcatactt ttttattagt tgtaggaata cagctttttg aaaaagctat 2600

 aaagtttaaa ttaactaaaa atatgcattt tcttacacat aatttaaatg 2650

 ttatcatact tttttgatga aaacataatg ccttagtaaa atagctctat 2700

 ttaataaaga agattgagta ctctgacaca tttcatttaa attaggaaat 2750

 ttttaatatt aaaatcccag tgttctgagt tattgaaagg ctttctttta 2800

 ttttgagagc tttaggtctt tttgggatga gaacatttta gttgtttagt 2850

 ttgtttctta agcagtgcta ttttttgtaa acacagataa atggaaacca 2900

 ttcttttcaa tgcagaagaa atctagatat cccctactgt gaccaaattt 2950

 ctgtattacg attttatgtt aaattaaact aatatggcag gttataatga 3000

 tccttaagtg taaagaaatc agtcaattac aagagtaatt gtatagttat 3050

 tgagacctat agtgtgtggc ttagatgaaa gggagagtaa attttcatac 3100

 catgctctct cctactcagt ttgatctctc taaaattgta gtttggtttg 3150

 atttaatata attcttagta gaaattttga aagtatgctt tgggattaat 3200

 aattattttt aatttttctg gctgaatatc aaattgatag taacaacaga 3250

 agcataattt taggaaggct ttcgcaaacc tagcctttta agagaggttt 3300

 ttaacctgaa gcatgagaat atatcacctg tggtttttcc tttgagatga 3350

 aacgtagttt ctagttatat cattacttaa agggcttaaa aagaaaaaac 3400

 ttagcaaact tttgaatctt tcttttattg ctatttacac atacatacac 3450

 acatacaaaa cctttaaatt ttgggatctg aatataattc tggtaaacag 3500

 ctgtcttcat ttttctcctc taaagaactt aattcatttg ttacataaaa 3550

 tataaggaaa tctttatact attttacagt aaccacaatc taaatattta 3600

 catataccca aaattaactt atgctcatat attaggatgt gagaatatca 3650

 tctgtttatg gacacatgaa acctcctaat gacctggaat tgttagaata 3700

 tttgactttt tatatgcaaa gtttttcaac caagtggttt gtctaatatt 3750

 taaacatgta ctggcacaat ttgtgatgaa aatattagca catttgcaat 3800

 aatgtttctc cataacagag aatgttaatg gataccagaa ttttattttt 3850

 gtatttatgt tcatagtact tttcctcttg tctactccag acagttattc 3900

 cataaagcat ttgtataatt aaaaggaaaa cagaaaaagg aaaagtaggc 3950

 aaatgtgaaa atagtttcaa tatatcttat gatttcttaa tgtaaaatgt 4000

 tttgttgaag tatatggcta tcatgactaa gtgctagaat ttatagttac 4050

 aggcggtgtc cttttaaatg tggaaaggct tttaaaatat tttaaaactg 4100

 gacctgtatt atcctgaata cactattttg aaaattttta agaaaaaaaa 4150

 aa 4152

<210> 6257
<211> 355
<212> PRT
<213> Homo sapien

<400> 6257
 Val Arg Gly Val Arg Ala Ala Thr Ala Ala Ala Val Ala Ala Thr
   1               5                  10                  15

 Ala Ala Ser Gly Leu Ser Arg Arg Glu Ala Gly Gly Arg Ala Gly
                  20                  25                  30

 Ala Ala Ala Ala Val Val Arg Pro Pro Gly Arg Lys Cys Gly Arg
                  35                  40                  45

 Cys Arg Arg Leu Ala Asn Phe Pro Gly Arg Lys Arg Arg Arg Arg
                  50                  55                  60

 Arg Arg Lys Gly Leu Gly Ala Thr Thr Gly Gly Cys Gly Glu Ala
                  65                  70                  75

 Val Ser Ser Leu His Pro Ala Pro His Ser Pro Ser Ser Val Arg
                  80                  85                  90

 Pro Ala Gly Arg Arg Ala Arg Arg Gln Arg Arg Gly Ala Gly Ser
                  95                 100                 105

 Ala Glu Arg Pro Met Ser Gly Ala Gly Glu Ala Leu Ala Pro Gly
                 110                 115                 120

 Pro Val Gly Pro Gln Arg Val Ala Glu Ala Gly Gly Gly Gln Leu
                 125                 130                 135

 Gly Ser Thr Ala Gln Gly Lys Cys Asp Lys Asp Asn Thr Glu Lys
                 140                 145                 150

 Asp Ile Thr Gln Ala Thr Asn Ser His Phe Thr His Gly Glu Met
                 155                 160                 165

 Gln Asp Gln Ser Ile Trp Gly Asn Pro Ser Asp Gly Glu Leu Ile
                 170                 175                 180

 Arg Thr Gln Pro Gln Arg Leu Pro Gln Leu Gln Thr Ser Ala Gln
                 185                 190                 195

 Val Pro Ser Gly Glu Glu Ile Gly Lys Ile Lys Asn Gly His Thr
                 200                 205                 210

 Gly Leu Ser Asn Gly Asn Gly Ile His His Gly Ala Lys His Gly
                 215                 220                 225

 Ser Ala Asp Asn Arg Lys Leu Ser Ala Pro Val Ser Gln Lys Met
                 230                 235                 240

 His Arg Lys Ile Gln Ser Ser Leu Ser Val Asn Ser Asp Ile Ser
                 245                 250                 255

 Lys Lys Ser Lys Val Asn Ala Val Phe Ser Gln Lys Thr Gly Ser
                 260                 265                 270

 Ser Pro Glu Asp Cys Cys Val His Cys Ile Leu Ala Cys Leu Phe
                 275                 280                 285

 Cys Glu Phe Leu Thr Leu Cys Asn Ile Val Leu Gly Gln Ala Ser
                 290                 295                 300

 Cys Gly Ile Cys Thr Ser Glu Ala Cys Cys Cys Cys Cys Gly Asp
                 305                 310                 315

 Glu Met Gly Asp Asp Cys Asn Cys Pro Cys Asp Met Asp Cys Gly
                 320                 325                 330

 Ile Met Asp Ala Cys Cys Glu Ser Ser Asp Cys Leu Glu Ile Cys
                 335                 340                 345

 Met Glu Cys Cys Gly Ile Cys Phe Pro Ser
                 350                 355

<210> 6258
<211> 3604
<212> DNA
<213> Homo sapien

<400> 6258
 aagaggctaa cctctgcttt gtggacattg acaaccactt cattgagttg 50

 ccagaggact tgccacagtt ccccaacaaa ttggagtttg tccaggaagt 100

 ctctgagatt ctcatggcat ttggaattcc ccctgaaggg aatcttcatt 150

 gcagtgagag tgcctccaag ctgaagaggc tgcgggcctc tgagcttgtc 200

 tcggacaaga ggaatgggaa cattgctggc tcccctttgc attcctacga 250

 gcttcttaag gagaatgaaa ctattgcccg gctgcaagcc ttggtcaaga 300

 gaactggggt gagcctggaa aagttggaag tgcgtgaaga ccccagcagc 350

 aataaggatc tcaaagttca gtgtgatgaa gaagaactca ggatttacca 400

 gctaaacatt cagatccggg aagtttttgc aaatcgtttc actcagatgt 450

 ttgcagatta tgaggtgttt gtcatccaac ccagccagga taaggaatcc 500

 tggtttacca acagggagca aatgcaaaac tttgataaag catcttttct 550

 gtcagatcag cctgagccct acctgccctt cctctcaaga ttcctggaga 600

 cccagatgtt tgcatctttc attgacaaca aaataatgtg tcatgatgat 650

 gatgatgaag accctgtact ccgggtattt gattcccgag ttgacaagat 700

 caggctgttg aatgttcgga cacctactct ccgtacatcc atgtaccaga 750

 agtgtaccac tgtggatgaa gcagagaaag caattgagct gcgtctggca 800

 aaaattgacc atactgcaat tcacccacat ttacttgaca tgaagattgg 850

 acaagggaaa tatgagccgg gcttcttccc taagctgcag tctgatgtac 900

 tttccactgg gccagccagc aacaagtgga cgaaaaggaa tgcccctgcc 950

 cagtggaggc ggaaagatcg gcagaagcag cacacagaac acctgcgttt 1000

 agataatgac cagagggaga agtacatcca ggaagccagg actatgggca 1050

 gcactatccg ccagcccaaa ctgtccaacc tctctccatc agtgattgcc 1100

 cagaccaatt ggaagtttgt agagggcctg ctgaaggaat gccgcaataa 1150

 gaccaagagg atgctggtgg aaaagatggg ccgagaagct gtggagctag 1200

 ggcatgggga ggtgaacatc acaggggtgg aagagaacac cctgattgcc 1250

 agcctttgtg atctcctgga aaggatctgg agtcatggac tacaagtgaa 1300

 acaggggaaa tcagccttat ggtcccacct gttacattat caggacaacc 1350

 ggcagagaaa actcacatca ggaagcctca gtacctcagg aatacttctt 1400

 gattcagaac gtaggaagtc tgatgccagc tcactcatgc ctcccctgag 1450

 gatctccctg attcaggata tgaggcacat ccagaacatc ggggaaatca 1500

 agactgatgt gggaaaggcc agagcatggg tgcgactgtc catggaaaaa 1550

 aagttacttt ccagacacct gaagcagctc ctctcagacc atgagctcac 1600

 caaaaagtta tataagcgct atgccttcct gcgctgtgat gacgagaagg 1650

 agcagttcct ctatcacctc ctgtctttca atgccgtcga ttacttttgc 1700

 ttcaccaatg tcttcacaac tatcctgatc ccgtaccaca ttctgatcgt 1750

 accaagcaag aagctggggg gctccatgtt cactgccaac ccatggatct 1800

 gtatatcagg agaattgggt gagacacaga tcatgcagat tcccaggaat 1850

 gtgctagaga tgaccttcga gtgccagaac ttggggaagc ttactactgt 1900

 ccagattggc catgataact ctgggctgta tgccaaatgg ctggtggagt 1950

 atgtgatggt caggaatgag atcacaggac atacctacaa gttcccgtgt 2000

 ggccggtggt tagggaaggg catggatgat ggaagcctgg agcggatcct 2050

 agttggggag ctgctcacat cccagcctga ggtggatgag aggccatgcc 2100

 ggaccccgcc gctgcagcag tcccccagtg tcatccggag gcttgttacc 2150

 atctcaccca acaacgagcc caagctgaac actgggcaga tccaggagtc 2200

 catcggggag gcagtcaatg gcattgtgaa gcacttccat aagcctgaga 2250

 aagagcgagg cagtctgacg ctgttgctct gtggagagtg tggccttgtc 2300

 tcggccttgg aacaggcttt ccagcatgga tttaaatcgc cccggctctt 2350

 caaaaatgtc ttcatttggg atttcctgga aaaagcacaa acctattatg 2400

 agacattaga gaagaatgaa gtagtccctg aggaaaactg gcatacaaga 2450

 gcccggaact tctgccgatt tgtcactgca atcaacaata ctccccggaa 2500

 catcggcaag gatggcaagt ttcagatgct ggtgtgcttg ggagccagag 2550

 atcacctcct acaccactgg attgccctgc tggctgactg ccccatcact 2600

 gcacacatgt atgaggatgt ggcactgatc aaagaccata cacttgtcaa 2650

 ttccttgatt cgtgtgctgc agacattgca ggagttcaac atcacgctgg 2700

 agacgtccct tgtcaagggc atcgacatct gacctcccag caccagccag 2750

 cagcaggact gagaaagact caccctgcag ctctgacctt ttttcccaaa 2800

 gggacttaag cgattgtgca ggagtaggag acaaaatgta cactcactgt 2850

 aaaaagaaaa ctagaggatt tttggaataa ataatctatt ttagagttta 2900

 tttgctgatt tgctttttac acactttcat gtgaaagagt gatagggaga 2950

 gggagcgagg ctggtgccgc ttattttgaa gctggtgccc tccctcgccg 3000

 tggccacatg ctggaagcct gaggcctccc tggactgagc ctgtggcact 3050

 gcgtgcggga cagttatgtt tccttgcccc gtcgcattaa tgaggccctt 3100

 ccacatcatt tttaaactaa tgtttttcta tattaacatt attatggata 3150

 tttggctttc ataggccaca cacaggtgtg ctgcgcggga agccccatgc 3200

 tccaatcaaa gggattttta gtagtgcctc taagcaagca ccgatgagtc 3250

 agtcccacgt attttctttt ttgtcagtat tgtttgggaa ggagacatgc 3300

 cgggatgtgt catcgtgcca aataccacat ttcctgttgg cacagtttca 3350

 cagaagtaaa cataagcatg ttttaacagg tttttctttt cttttttctt 3400

 ttttaaaatg ttttatttat ttaacccgcc attgtgtgtt tttaagtatt 3450

 ttcttttttt aaggaaagga aaagcttgtc acaatctaac tggctatgtt 3500

 attattatta aatttatgtt ttgcaactta gaaaccagct acagtatggc 3550

 ccacttaata aaacacctga aacaaaaaaa aaaaaaaaaa aaaaaaaaaa 3600

 aaaa 3604

<210> 6259
<211> 872
<212> PRT
<213> Homo sapien

<400> 6259
 Met Ala Phe Gly Ile Pro Pro Glu Gly Asn Leu His Cys Ser Glu
   1               5                  10                  15

 Ser Ala Ser Lys Leu Lys Arg Leu Arg Ala Ser Glu Leu Val Ser
                  20                  25                  30

 Asp Lys Arg Asn Gly Asn Ile Ala Gly Ser Pro Leu His Ser Tyr
                  35                  40                  45

 Glu Leu Leu Lys Glu Asn Glu Thr Ile Ala Arg Leu Gln Ala Leu
                  50                  55                  60

 Val Lys Arg Thr Gly Val Ser Leu Glu Lys Leu Glu Val Arg Glu
                  65                  70                  75

 Asp Pro Ser Ser Asn Lys Asp Leu Lys Val Gln Cys Asp Glu Glu
                  80                  85                  90

 Glu Leu Arg Ile Tyr Gln Leu Asn Ile Gln Ile Arg Glu Val Phe
                  95                 100                 105

 Ala Asn Arg Phe Thr Gln Met Phe Ala Asp Tyr Glu Val Phe Val
                 110                 115                 120

 Ile Gln Pro Ser Gln Asp Lys Glu Ser Trp Phe Thr Asn Arg Glu
                 125                 130                 135

 Gln Met Gln Asn Phe Asp Lys Ala Ser Phe Leu Ser Asp Gln Pro
                 140                 145                 150

 Glu Pro Tyr Leu Pro Phe Leu Ser Arg Phe Leu Glu Thr Gln Met
                 155                 160                 165

 Phe Ala Ser Phe Ile Asp Asn Lys Ile Met Cys His Asp Asp Asp
                 170                 175                 180

 Asp Glu Asp Pro Val Leu Arg Val Phe Asp Ser Arg Val Asp Lys
                 185                 190                 195

 Ile Arg Leu Leu Asn Val Arg Thr Pro Thr Leu Arg Thr Ser Met
                 200                 205                 210

 Tyr Gln Lys Cys Thr Thr Val Asp Glu Ala Glu Lys Ala Ile Glu
                 215                 220                 225

 Leu Arg Leu Ala Lys Ile Asp His Thr Ala Ile His Pro His Leu
                 230                 235                 240

 Leu Asp Met Lys Ile Gly Gln Gly Lys Tyr Glu Pro Gly Phe Phe
                 245                 250                 255

 Pro Lys Leu Gln Ser Asp Val Leu Ser Thr Gly Pro Ala Ser Asn
                 260                 265                 270

 Lys Trp Thr Lys Arg Asn Ala Pro Ala Gln Trp Arg Arg Lys Asp
                 275                 280                 285

 Arg Gln Lys Gln His Thr Glu His Leu Arg Leu Asp Asn Asp Gln
                 290                 295                 300

 Arg Glu Lys Tyr Ile Gln Glu Ala Arg Thr Met Gly Ser Thr Ile
                 305                 310                 315

 Arg Gln Pro Lys Leu Ser Asn Leu Ser Pro Ser Val Ile Ala Gln
                 320                 325                 330

 Thr Asn Trp Lys Phe Val Glu Gly Leu Leu Lys Glu Cys Arg Asn
                 335                 340                 345

 Lys Thr Lys Arg Met Leu Val Glu Lys Met Gly Arg Glu Ala Val
                 350                 355                 360

 Glu Leu Gly His Gly Glu Val Asn Ile Thr Gly Val Glu Glu Asn
                 365                 370                 375

 Thr Leu Ile Ala Ser Leu Cys Asp Leu Leu Glu Arg Ile Trp Ser
                 380                 385                 390

 His Gly Leu Gln Val Lys Gln Gly Lys Ser Ala Leu Trp Ser His
                 395                 400                 405

 Leu Leu His Tyr Gln Asp Asn Arg Gln Arg Lys Leu Thr Ser Gly
                 410                 415                 420

 Ser Leu Ser Thr Ser Gly Ile Leu Leu Asp Ser Glu Arg Arg Lys
                 425                 430                 435

 Ser Asp Ala Ser Ser Leu Met Pro Pro Leu Arg Ile Ser Leu Ile
                 440                 445                 450

 Gln Asp Met Arg His Ile Gln Asn Ile Gly Glu Ile Lys Thr Asp
                 455                 460                 465

 Val Gly Lys Ala Arg Ala Trp Val Arg Leu Ser Met Glu Lys Lys
                 470                 475                 480

 Leu Leu Ser Arg His Leu Lys Gln Leu Leu Ser Asp His Glu Leu
                 485                 490                 495

 Thr Lys Lys Leu Tyr Lys Arg Tyr Ala Phe Leu Arg Cys Asp Asp
                 500                 505                 510

 Glu Lys Glu Gln Phe Leu Tyr His Leu Leu Ser Phe Asn Ala Val
                 515                 520                 525

 Asp Tyr Phe Cys Phe Thr Asn Val Phe Thr Thr Ile Leu Ile Pro
                 530                 535                 540

 Tyr His Ile Leu Ile Val Pro Ser Lys Lys Leu Gly Gly Ser Met
                 545                 550                 555

 Phe Thr Ala Asn Pro Trp Ile Cys Ile Ser Gly Glu Leu Gly Glu
                 560                 565                 570

 Thr Gln Ile Met Gln Ile Pro Arg Asn Val Leu Glu Met Thr Phe
                 575                 580                 585

 Glu Cys Gln Asn Leu Gly Lys Leu Thr Thr Val Gln Ile Gly His
                 590                 595                 600

 Asp Asn Ser Gly Leu Tyr Ala Lys Trp Leu Val Glu Tyr Val Met
                 605                 610                 615

 Val Arg Asn Glu Ile Thr Gly His Thr Tyr Lys Phe Pro Cys Gly
                 620                 625                 630

 Arg Trp Leu Gly Lys Gly Met Asp Asp Gly Ser Leu Glu Arg Ile
                 635                 640                 645

 Leu Val Gly Glu Leu Leu Thr Ser Gln Pro Glu Val Asp Glu Arg
                 650                 655                 660

 Pro Cys Arg Thr Pro Pro Leu Gln Gln Ser Pro Ser Val Ile Arg
                 665                 670                 675

 Arg Leu Val Thr Ile Ser Pro Asn Asn Glu Pro Lys Leu Asn Thr
                 680                 685                 690

 Gly Gln Ile Gln Glu Ser Ile Gly Glu Ala Val Asn Gly Ile Val
                 695                 700                 705

 Lys His Phe His Lys Pro Glu Lys Glu Arg Gly Ser Leu Thr Leu
                 710                 715                 720

 Leu Leu Cys Gly Glu Cys Gly Leu Val Ser Ala Leu Glu Gln Ala
                 725                 730                 735

 Phe Gln His Gly Phe Lys Ser Pro Arg Leu Phe Lys Asn Val Phe
                 740                 745                 750

 Ile Trp Asp Phe Leu Glu Lys Ala Gln Thr Tyr Tyr Glu Thr Leu
                 755                 760                 765

 Glu Lys Asn Glu Val Val Pro Glu Glu Asn Trp His Thr Arg Ala
                 770                 775                 780

 Arg Asn Phe Cys Arg Phe Val Thr Ala Ile Asn Asn Thr Pro Arg
                 785                 790                 795

 Asn Ile Gly Lys Asp Gly Lys Phe Gln Met Leu Val Cys Leu Gly
                 800                 805                 810

 Ala Arg Asp His Leu Leu His His Trp Ile Ala Leu Leu Ala Asp
                 815                 820                 825

 Cys Pro Ile Thr Ala His Met Tyr Glu Asp Val Ala Leu Ile Lys
                 830                 835                 840

 Asp His Thr Leu Val Asn Ser Leu Ile Arg Val Leu Gln Thr Leu
                 845                 850                 855

 Gln Glu Phe Asn Ile Thr Leu Glu Thr Ser Leu Val Lys Gly Ile
                 860                 865                 870

 Asp Ile


<210> 6260
<211> 4572
<212> DNA
<213> Homo sapien

<400> 6260
 ggcggcgcta gcttcggagt ctcccgcgcg cacctcagcc gcctcctagc 50

 ggcgcggcgc tcgctcctac gcctaaaatg accaatgtgt gatttcagtg 100

 gaataaatgg cgtccaaagt cacagatgct atagtctggt atcaaaagaa 150

 gattggagca tatgatcaac aaatatggga aaaatctgtt gaacagagag 200

 aaatcaaggg gctaaggaat aaaccaaaga aaacagcaca tgtgaaacca 250

 gacctcatag atgttgatct tgtaagaggg tctgcatttg caaaggcaaa 300

 gcctgaaagt ccttggactt ctctgaccag aaagggaatt gttcgagttg 350

 tatttttccc ctttttcttc cggtggtggt tacaagtaac atcaaaggtc 400

 atctttttct ggcttcttgt cctttatctt cttcaagttg ctgcaatagt 450

 attattctgc tccacttcta gcccacacag catacctctg acagaggtga 500

 ttgggccgat atggctgatg ctgctcctgg gaactgtgca ttgccagatt 550

 gtttccacaa gaacacccaa acctcctcta agtacagggg gtaaaagaag 600

 aaggaaatta agaaaagcag cccatttgga agtacatagg gaaggagatg 650

 gttctagtac cacagataac acacaagagg gagcagttca gaaccacggt 700

 acaagcacct ctcacagcgt tggcactgtc ttcagagatc tctggcatgc 750

 tgctttcttt ttatcaggat caaagaaagc aaagaattca attgataaat 800

 caactgaaac tgacaatggc tatgtatccc ttgatgggaa gaagactgtt 850

 aaaagcggtg aagatggaat acaaaaccat gaacctcagt gtgaaactat 900

 tcgaccagaa gagacagcct ggaacacagg aacactgagg aatggtccta 950

 gcaaagatac ccaaaggaca ataacaaatg tctctgatga agtctccagt 1000

 gaggaaggtc ctgaaacagg atactcatta cgtcgtcatg tggacaggac 1050

 ttctgaaggt gttcttcgga atagaaagtc acaccattat aagaaacatt 1100

 accctaatga ggacgcccct aaatcgggta ctagttgcag ctctcgctgt 1150

 tcaagttcca gacaggattc tgagagtgca aggccagaat ctgaaacaga 1200

 agatgtgtta tgggaagact tgttacattg tgcagaatgc cattcatctt 1250

 gtaccagtga gacagatgtg gaaaatcatc agattaatcc atgtgtgaaa 1300

 aaagaatata gagatgaccc ttttcatcag agtcatttgc cctggctcca 1350

 tagttcccac ccaggattag aaaaaataag tgctatagta tgggaaggta 1400

 atgattgtaa gaaagcagac atgtctgtac ttgaaatcag tggaatgata 1450

 atgaacagag tgaacagcca tataccagga ataggatacc agatttttgg 1500

 aaatgcagtc tctctcatac tgggtttaac tccatttgtt ttccgacttt 1550

 ctcaagctac agacttggaa caactcacag cacattctgc ttcagaactt 1600

 tatgtgattg catttggttc taatgaagat gtcatagttc tttctatggt 1650

 tataataagt tttgtggttc gcgtgtctct tgtgtggatt ttcttttttt 1700

 tgctctgtgt agcagaaaga acttataaac agcgattact ttttgcaaaa 1750

 ctctttggac atttaacatc tgcaaggagg gctcgaaaat ctgaggttcc 1800

 tcatttccgg ttgaagaaag tacagaatat aaaaatgtgg ctatctctcc 1850

 gttcctatct taagcgtcga ggtcctcagc gatcagttga tgtaatagtt 1900

 tcatctgctt tcttattgac tatctcagtt gtatttatct gttgtgccca 1950

 gataaacctc tacttgaaaa tggagaaaaa acctaacaaa aaggaggaac 2000

 tgacactagt gaataatgtt ttaaaactgg ctactaaact gctaaaggag 2050

 ttggacagtc cttttagatt atatgggctt acaatgaatc cgctgcttta 2100

 taacatcacc caggttgtta tcctgtcagc tgtttctggt gttatcagtg 2150

 acttgcttgg atttaattta aagctatgga agattaagtc atgacaattc 2200

 aaagaaaaga agatgtagcc tcttttccag aataagagta ctgactaagc 2250

 tgcctgaaag cttgtcactg attctttgct tcaggagtct cagctaggga 2300

 gttgaagtgt ttacatcaga ctgtcttgtg caattcttat atttatttta 2350

 ctggttcact tttttttaca tttattttag tctttatatt tttattttta 2400

 agcattgatg tacttagttg ttgaaagggt gatgaaactg atatccagat 2450

 acttgagatc ctggtaattg gtcataaata attggcaaaa taacaaattg 2500

 tgaaaataga agccattgct cagcaccgtt tctccatcaa tgccgtgaac 2550

 ttgccttact tgaggaaaaa ttctttaact ttggaatatt gcattgaact 2600

 cagctataca cataaaacat tttctttggt aaatcaagat ccagtcaggg 2650

 tttctcttga attattttgg aacaatgcca ggatccaaac tgattaagtt 2700

 acagtttaag cacccttcag tattaatata tacggtatta tataacaggt 2750

 caacaagtgc tctttgatga taaaacttgt aatagagcaa taattgtaaa 2800

 tggttaccat actgtaagat attttgataa aaattaacta gtaatacttg 2850

 tatttatttg aaacactggg ctgtttgcac agctccaact gtgcatgctc 2900

 aaaatgtgca ctttttaaaa ttgttacttt taatgcgtat ctttatatgg 2950

 gatctgttat agtatactag ggcatgatat ggtatccttt tgagtgaggt 3000

 atatactcat ctcacaagtg aagtgcctac tgatattact aaagtacatt 3050

 atgtttactc aagtaaataa ttttctcccc atggtacact ctagtgtagg 3100

 ctattcatac cacactgaaa tgaacaactg aagaataagg ctaagaacca 3150

 ataaaatatt tctctaattg ctagttgtaa aactgtatcc aaattttcag 3200

 aaaagacagc ttcagcttgc aaattctatc ctctaaactt atctggtgca 3250

 ttctccccac cccaccccca ttatataagg gctattttag atgcttttaa 3300

 cctccccaac aaataatttg ccaagtgtcc aatgagaact tatcatgttg 3350

 gtgtgttagg taaatcgggc aaatatgata gtgtcttaca ttgggccttg 3400

 attttaagtt gttatatttg tacaatcgag tattttagaa attacatgaa 3450

 acatgaaaca gtttttgcaa ttttttttaa actgggcatc tggtttctaa 3500

 aaatttattt gaaacaatct agaattttct tggtgcaaag tgtatcatgt 3550

 ggaatatcct catattttta ccatatttta agaactttaa gacgattaat 3600

 tgtaaataat ttatttgatt ggtgcagttc taatccctaa atcataatct 3650

 taaaatcagg aatgtgtgga gaacagagcc atgtcatatc actttgctct 3700

 taccattcct tttgatcagc ctcaattcag cctcattgtg tagtatgttt 3750

 tttctttcta tgaaaaacaa cagaaagcat ttcattttat ttgcctatgt 3800

 tcaaatatgt ttaataatga ccaaagtgca ttctgagttt tttcaaggaa 3850

 tgtaatactg gagctttaag aacatactta gtttctcatg tgaaaactta 3900

 ggctttgtct gatgtttttc cttcctctat tgtctaatgt tgaggttgtt 3950

 tttaggaatt atgttttata aactttttca atataaggta catgcctata 4000

 cagaacttaa cattttgcac agaatatatc aaatatattt tgagaaaaaa 4050

 agtacggcat gagttctgtt aggaataaaa gatgaaacta ttgtatctca 4100

 caaaaaatct tatttcagaa tggaaatatt tttgagaaaa gtagctgagt 4150

 atactggttt aagaaaatgc ttgttttaga ttgaggttaa cttagagttg 4200

 ggagttgatt tattaagtac agtatacctc tcaacagttt ataaataata 4250

 tgttgaatta tgtcagtgtg ggcagcagta gaatactaaa aggaaaatgt 4300

 catgttaagc aatttcagaa cattaactga actattttca aagcagaaaa 4350

 attgacattg ctgcctttaa gaataccatg aatgtaagaa attgaaagaa 4400

 attgtaaaat atcacataat atagaaatgg cagttcaaag agaattgtgg 4450

 cagatgttgt gtgtgaactg ttgtttcttt gccacatgtg ttgtatttga 4500

 aagttttaca gtaagtttaa aataaaacat tctgtgactg aaaaaaaaaa 4550

 aaaaaaaaaa aaaaaaaaaa aa 4572

<210> 6261
<211> 695
<212> PRT
<213> Homo sapien

<400> 6261
 Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys
   1               5                  10                  15

 Ile Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln
                  20                  25                  30

 Arg Glu Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His
                  35                  40                  45

 Val Lys Pro Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala
                  50                  55                  60

 Phe Ala Lys Ala Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg
                  65                  70                  75

 Lys Gly Ile Val Arg Val Val Phe Phe Pro Phe Phe Phe Arg Trp
                  80                  85                  90

 Trp Leu Gln Val Thr Ser Lys Val Ile Phe Phe Trp Leu Leu Val
                  95                 100                 105

 Leu Tyr Leu Leu Gln Val Ala Ala Ile Val Leu Phe Cys Ser Thr
                 110                 115                 120

 Ser Ser Pro His Ser Ile Pro Leu Thr Glu Val Ile Gly Pro Ile
                 125                 130                 135

 Trp Leu Met Leu Leu Leu Gly Thr Val His Cys Gln Ile Val Ser
                 140                 145                 150

 Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr Gly Gly Lys Arg Arg
                 155                 160                 165

 Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val His Arg Glu Gly
                 170                 175                 180

 Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly Ala Val Gln
                 185                 190                 195

 Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val Phe Arg
                 200                 205                 210

 Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys Ala
                 215                 220                 225

 Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val
                 230                 235                 240

 Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile
                 245                 250                 255

 Gln Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr
                 260                 265                 270

 Ala Trp Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr
                 275                 280                 285

 Gln Arg Thr Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu
                 290                 295                 300

 Gly Pro Glu Thr Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr
                 305                 310                 315

 Ser Glu Gly Val Leu Arg Asn Arg Lys Ser His His Tyr Lys Lys
                 320                 325                 330

 His Tyr Pro Asn Glu Asp Ala Pro Lys Ser Gly Thr Ser Cys Ser
                 335                 340                 345

 Ser Arg Cys Ser Ser Ser Arg Gln Asp Ser Glu Ser Ala Arg Pro
                 350                 355                 360

 Glu Ser Glu Thr Glu Asp Val Leu Trp Glu Asp Leu Leu His Cys
                 365                 370                 375

 Ala Glu Cys His Ser Ser Cys Thr Ser Glu Thr Asp Val Glu Asn
                 380                 385                 390

 His Gln Ile Asn Pro Cys Val Lys Lys Glu Tyr Arg Asp Asp Pro
                 395                 400                 405

 Phe His Gln Ser His Leu Pro Trp Leu His Ser Ser His Pro Gly
                 410                 415                 420

 Leu Glu Lys Ile Ser Ala Ile Val Trp Glu Gly Asn Asp Cys Lys
                 425                 430                 435

 Lys Ala Asp Met Ser Val Leu Glu Ile Ser Gly Met Ile Met Asn
                 440                 445                 450

 Arg Val Asn Ser His Ile Pro Gly Ile Gly Tyr Gln Ile Phe Gly
                 455                 460                 465

 Asn Ala Val Ser Leu Ile Leu Gly Leu Thr Pro Phe Val Phe Arg
                 470                 475                 480

 Leu Ser Gln Ala Thr Asp Leu Glu Gln Leu Thr Ala His Ser Ala
                 485                 490                 495

 Ser Glu Leu Tyr Val Ile Ala Phe Gly Ser Asn Glu Asp Val Ile
                 500                 505                 510

 Val Leu Ser Met Val Ile Ile Ser Phe Val Val Arg Val Ser Leu
                 515                 520                 525

 Val Trp Ile Phe Phe Phe Leu Leu Cys Val Ala Glu Arg Thr Tyr
                 530                 535                 540

 Lys Gln Arg Leu Leu Phe Ala Lys Leu Phe Gly His Leu Thr Ser
                 545                 550                 555

 Ala Arg Arg Ala Arg Lys Ser Glu Val Pro His Phe Arg Leu Lys
                 560                 565                 570

 Lys Val Gln Asn Ile Lys Met Trp Leu Ser Leu Arg Ser Tyr Leu
                 575                 580                 585

 Lys Arg Arg Gly Pro Gln Arg Ser Val Asp Val Ile Val Ser Ser
                 590                 595                 600

 Ala Phe Leu Leu Thr Ile Ser Val Val Phe Ile Cys Cys Ala Gln
                 605                 610                 615

 Ile Asn Leu Tyr Leu Lys Met Glu Lys Lys Pro Asn Lys Lys Glu
                 620                 625                 630

 Glu Leu Thr Leu Val Asn Asn Val Leu Lys Leu Ala Thr Lys Leu
                 635                 640                 645

 Leu Lys Glu Leu Asp Ser Pro Phe Arg Leu Tyr Gly Leu Thr Met
                 650                 655                 660

 Asn Pro Leu Leu Tyr Asn Ile Thr Gln Val Val Ile Leu Ser Ala
                 665                 670                 675

 Val Ser Gly Val Ile Ser Asp Leu Leu Gly Phe Asn Leu Lys Leu
                 680                 685                 690

 Trp Lys Ile Lys Ser
                 695

<210> 6262
<211> 873
<212> DNA
<213> Homo sapien

<400> 6262
 acttcccctt cctgtacagg gcaggttgtg cagctggagg cagagcagtc 50

 ctctctgggg agcctgaagc aaacatggat caagaaactg taggcaatgt 100

 tgtcctgttg gccatcgtca ccctcatcag cgtggtccag aatggattct 150

 ttgcccataa agtggagcac gaaagcagga cccagaatgg gaggagcttc 200

 cagaggaccg gaacacttgc ctttgagcgg gtctacactg ccaaccagaa 250

 ctgtgtagat gcgtacccca ctttcctcgc tgtgctctgg tctgcggggc 300

 tactttgcag ccaagttcct gctgcgtttg ctggactgat gtacttgttt 350

 gtgaggcaaa agtactttgt cggttaccta ggagagagaa cgcagagcac 400

 ccctggctac atatttggga aacgcatcat actcttcctg ttcctcatgt 450

 ccgttgctgg catattcaac tattacctca tcttcttttt cggaagtgac 500

 tttgaaaact acataaagac gatctccacc accatctccc ctctacttct 550

 cattccctaa ctctctgctg aatatggggt tggtgttctc atctaatcaa 600

 tacctacaag tcatcataat tcagctcttg agagcattct gctcttcttt 650

 agatggctgt aaatctattg gccatctggg cttcacagct tgagttaacc 700

 ttgcttttcc gggaacaaaa tgatgtcatg tcagctccgc cccttgaaca 750

 tgaccgtggc cccaaatttg ctattcccat gcattttgtt tgtttcttca 800

 cttatcctgt tctctgaaga tgttttgtga ccaggtttgt gttttcttaa 850

 aataaaatgc agagacatgt ttt 873

<210> 6263
<211> 161
<212> PRT
<213> Homo sapien

<400> 6263
 Met Asp Gln Glu Thr Val Gly Asn Val Val Leu Leu Ala Ile Val
   1               5                  10                  15

 Thr Leu Ile Ser Val Val Gln Asn Gly Phe Phe Ala His Lys Val
                  20                  25                  30

 Glu His Glu Ser Arg Thr Gln Asn Gly Arg Ser Phe Gln Arg Thr
                  35                  40                  45

 Gly Thr Leu Ala Phe Glu Arg Val Tyr Thr Ala Asn Gln Asn Cys
                  50                  55                  60

 Val Asp Ala Tyr Pro Thr Phe Leu Ala Val Leu Trp Ser Ala Gly
                  65                  70                  75

 Leu Leu Cys Ser Gln Val Pro Ala Ala Phe Ala Gly Leu Met Tyr
                  80                  85                  90

 Leu Phe Val Arg Gln Lys Tyr Phe Val Gly Tyr Leu Gly Glu Arg
                  95                 100                 105

 Thr Gln Ser Thr Pro Gly Tyr Ile Phe Gly Lys Arg Ile Ile Leu
                 110                 115                 120

 Phe Leu Phe Leu Met Ser Val Ala Gly Ile Phe Asn Tyr Tyr Leu
                 125                 130                 135

 Ile Phe Phe Phe Gly Ser Asp Phe Glu Asn Tyr Ile Lys Thr Ile
                 140                 145                 150

 Ser Thr Thr Ile Ser Pro Leu Leu Leu Ile Pro
                 155                 160

<210> 6264
<211> 4357
<212> DNA
<213> Homo sapien

<400> 6264
 atagtcacca gaagctggaa gagtcaaagg acacattctc ccctcaagcc 50

 ccagtgggag cacggcccag ctggattttg gacttctggc ctccagaact 100

 agacagggcc tcacggtgtc acccagggtg gaatacagtg gtgtgatcat 150

 agctcactgc agcctggaat tcctgggctc aagcaaccct gccacctcag 200

 ccttccaagt agctaggact acagaacatc catgatagca gtcttctgta 250

 aatcgaactt ttcaagaatt ctctgaagga accaagtagg atattcttac 300

 atcatgactt aatgtgaatg caagaacaag aaataggttt tatctctaaa 350

 tataatgaag ggctgtgtgt aaacactgac cctgtctcaa ttctaacaag 400

 cattttagac atgagtttac atcggcaaat gggttcagat cgagatcttc 450

 agtcctctgc ttcatctgtg agcttgcctt cagtcaaaaa ggcacccaaa 500

 aaaagaagaa tttcaatagg ctccctgttt cggaggaaaa aagataacaa 550

 acgtaaatca agggagctaa atggcggggt ggatggaatt gcaagtattg 600

 aaagtataca ttctgaaatg tgtactgata agaactccat tttctctaca 650

 aatacctctt ctgacaatgg attaacttcc atcagcaaac aaattggaga 700

 cttcatagag tgccctttgt gccttttgcg gcattctaaa gacagatttc 750

 ctgatataat gacttgtcat cacagatctt gtgtggattg cttacgacaa 800

 tatttaagga tagaaatctc tgaaagcaga gttaatatta gttgcccaga 850

 atgtactgag cggtttaatc cccatgatat tcgcttgata ttaagtgatg 900

 atgtcttgat ggaaaaatac gaagaattta tgcttagacg gtggcttgtt 950

 gcagatcctg attgtaggtg gtgtccagct ccagactgtg gatatgctgt 1000

 gatagcattt ggatgtgcca gctgtccaaa attaacttgt gggcgagagg 1050

 gctgtggaac agagttttgc taccactgta aacagatttg gcaccccaac 1100

 cagacctgtg atgctgctcg acaagagaga gcccagagct tacgtttgag 1150

 aactatacgt tcttcatcca ttagttatag tcaagagtct ggagcagcag 1200

 ctgatgatat aaagccatgt ccacgatgtg ctgcttatat aataaagatg 1250

 aatgatggga gctgcaatca catgacatgt gctgtttgtg gttgtgagtt 1300

 ttgttggttg tgtatgaaag aaatctcaga tttgcattat ctaagtccat 1350

 caggatgtac tttttggggg aagaaaccct ggagccgaaa gaagaaaata 1400

 ttgtggcaac tgggaacact ggttggtgct cctgtcggaa tcgctttaat 1450

 agctggcatt gctattcctg caatgattat tggcattcct gtgtatgtgg 1500

 gccgcaagat tcacaatcgc tatgaaggca aggatgtttc aaagcacaaa 1550

 cggaatttgg ccatagcagg tggtgtaacg ttgtctgtaa tcgtgtctcc 1600

 agtagtagct gcagtgactg taggtatcgg tgttcctatt atgttagctt 1650

 atgtctatgg cgtagttcca atttctcttt gtcgaagcgg aggttgtgga 1700

 gtctcagcag gcaatggaaa aggagttagg attgaatttg atgatgaaaa 1750

 tgatataaat gttggtggaa ctaacacagc tgtagacaca acatcagtag 1800

 cagaagcaag acacaaccca agcatagggg agggaagtgt tggtgggctg 1850

 actggcagtt tgagtgcaag tggaagccac atggatcgaa taggagccat 1900

 ccgagacaac ctgagtgaaa cggccagcac catggcacta gctggagcca 1950

 gtataacggg gagtctgtca ggaagtgcca tggtaaactg ttttaacagg 2000

 ttggaagtac aagcagatgt acagaaagaa cggtacagtc taagtggaga 2050

 atctggcaca gtcagcttgg gaacagttag tgataatgcc agcaccaaag 2100

 caatggcagg atccattctg aattcctaca tcccattgga caaagaaggc 2150

 aacagtatgg aggtgcaagt agatattgag tcaaagccat ccaaattcag 2200

 gcacaacagt ggaagcagta gtgtggatga tggcagtgcc acccgaagtt 2250

 atgctggcgg ttcatccagt ggcttgcctg aaggtaaatc tagtgccacc 2300

 aagtggtcca aagaagcaac agcagggaaa aaatcaaaaa gtggtaaact 2350

 gaggaaaaag ggtaacatga agataaatga gacgagagag gacatggatg 2400

 cacagttgtt agaacaacaa agcacgaact caagtgaatt tgaggctcca 2450

 tccctcagtg acagtatgcc ttctgtagca gattctcact ctagtcattt 2500

 ttctgaattt agttgttctg acctagaaag catgaaaact tcttgtagtc 2550

 atggttccag tgattatcac acccgctttg ctactgttaa cattcttcct 2600

 gaggtagaaa atgaccgtct ggaaaattcc ccacatcagt gtagcatttc 2650

 tgtggttacc caaactgctt cctgttcaga agtttcacag ttgaatcata 2700

 ttgctgaaga acatggtaac aatggaataa aacctaatgt tgatttatat 2750

 tttggcgatg cactaaaaga aacaaataac aaccactcac atcagacaat 2800

 ggaattaaaa gttgcaattc agactgaaat ttaggcccat aaatgctgca 2850

 gaataattac cactgtacaa ccgtgtttgg agctggttga actacatgtg 2900

 actacttaag tttcaggtta ccagcaaaag ccgggtttca ttatcataat 2950

 gcagatacat tttctgtgtt cagcaaggca ttgtgtgtca tgtggatctt 3000

 agttaccaaa ctatgaagtg aaggctttaa aagtgcatta ttttaaggat 3050

 aataaatttg aagagcaaag catgttttgt gtgtttgcca caaaacattg 3100

 cttgaagcac atacttagat agaaattggt cttaatttat ataatcaata 3150

 taaaatacta atgcaattct acagcattca aatgaagaaa acttgaggct 3200

 ttagggataa gtggttagtg atattttatt gaaaccacta aagagataag 3250

 tttaaaagaa ctgcataggt tactctcagt atatgatact ctgtaacatt 3300

 tctatttata tcggcataaa tttcattttt tttcttcata tgcaatgtgg 3350

 ttatataaag cttaatgcag ctcatttgct accatttgga tacttagaca 3400

 ctttgagcaa gattgtggca gtttttgcac aactttgaaa tagaaatacc 3450

 tggtactcta tcttgtttat tgttgatgcc atcttagagg aaaaaatgta 3500

 aaggtaagta attaagcata tgacagcaac aaataagata cataaaacta 3550

 caaaataaag tcccattagg ttataagtat tacaaaaaat ccacctttct 3600

 ctaaggggaa gtttgtaccc cattgattct tggtgccttt gggatcgact 3650

 gggttttaat ggcctagtta tttgaggatt ttgctgtgtt gttttccatg 3700

 tcttctctgg tcaccttgga ttatatataa aaatacagga aatagataaa 3750

 catgaatgtg attaataatg ctgaaaaagt attagcctac caaagacaca 3800

 ctcaggcttt agtgaataac tttacataac ctcagttttt aacacatgca 3850

 tatcttctcc aaccatgaaa tcaaagcacg gtgcagaact tgtaccaagt 3900

 acaaaaggtc catgtatgat tagcattatt ttcttttgct tttgtttatg 3950

 gacaatgttc agctgacata agcagaagtt ggccaaaata ctgcctgtac 4000

 tgttaatttc ctgtataatt cacttaaata aaagcaggtt aacctcaatg 4050

 atagcagtta aaatgttcta tcttatgtat ttcttttaag tattaccatt 4100

 atggtgctac tgagcgtttt cttttggtaa aaagaaaaat gccatgggct 4150

 gcagtcttct tccatcactt ttccctacca ggtccattaa tatgcttata 4200

 acactagtgc cagttatttt atttgataat gcttatggta tttgtatatt 4250

 tgtttgcatt ccaattttgt ttaataatga gtgtgtaaac tgcatacgtt 4300

 aaataaatgt aaatactaat gtactgctgc aaaaaaaaaa aaaaaaaaaa 4350

 aaaaaaa 4357

<210> 6265
<211> 838
<212> PRT
<213> Homo sapien

<400> 6265
 Met Gln Glu Gln Glu Ile Gly Phe Ile Ser Lys Tyr Asn Glu Gly
   1               5                  10                  15

 Leu Cys Val Asn Thr Asp Pro Val Ser Ile Leu Thr Ser Ile Leu
                  20                  25                  30

 Asp Met Ser Leu His Arg Gln Met Gly Ser Asp Arg Asp Leu Gln
                  35                  40                  45

 Ser Ser Ala Ser Ser Val Ser Leu Pro Ser Val Lys Lys Ala Pro
                  50                  55                  60

 Lys Lys Arg Arg Ile Ser Ile Gly Ser Leu Phe Arg Arg Lys Lys
                  65                  70                  75

 Asp Asn Lys Arg Lys Ser Arg Glu Leu Asn Gly Gly Val Asp Gly
                  80                  85                  90

 Ile Ala Ser Ile Glu Ser Ile His Ser Glu Met Cys Thr Asp Lys
                  95                 100                 105

 Asn Ser Ile Phe Ser Thr Asn Thr Ser Ser Asp Asn Gly Leu Thr
                 110                 115                 120

 Ser Ile Ser Lys Gln Ile Gly Asp Phe Ile Glu Cys Pro Leu Cys
                 125                 130                 135

 Leu Leu Arg His Ser Lys Asp Arg Phe Pro Asp Ile Met Thr Cys
                 140                 145                 150

 His His Arg Ser Cys Val Asp Cys Leu Arg Gln Tyr Leu Arg Ile
                 155                 160                 165

 Glu Ile Ser Glu Ser Arg Val Asn Ile Ser Cys Pro Glu Cys Thr
                 170                 175                 180

 Glu Arg Phe Asn Pro His Asp Ile Arg Leu Ile Leu Ser Asp Asp
                 185                 190                 195

 Val Leu Met Glu Lys Tyr Glu Glu Phe Met Leu Arg Arg Trp Leu
                 200                 205                 210

 Val Ala Asp Pro Asp Cys Arg Trp Cys Pro Ala Pro Asp Cys Gly
                 215                 220                 225

 Tyr Ala Val Ile Ala Phe Gly Cys Ala Ser Cys Pro Lys Leu Thr
                 230                 235                 240

 Cys Gly Arg Glu Gly Cys Gly Thr Glu Phe Cys Tyr His Cys Lys
                 245                 250                 255

 Gln Ile Trp His Pro Asn Gln Thr Cys Asp Ala Ala Arg Gln Glu
                 260                 265                 270

 Arg Ala Gln Ser Leu Arg Leu Arg Thr Ile Arg Ser Ser Ser Ile
                 275                 280                 285

 Ser Tyr Ser Gln Glu Ser Gly Ala Ala Ala Asp Asp Ile Lys Pro
                 290                 295                 300

 Cys Pro Arg Cys Ala Ala Tyr Ile Ile Lys Met Asn Asp Gly Ser
                 305                 310                 315

 Cys Asn His Met Thr Cys Ala Val Cys Gly Cys Glu Phe Cys Trp
                 320                 325                 330

 Leu Cys Met Lys Glu Ile Ser Asp Leu His Tyr Leu Ser Pro Ser
                 335                 340                 345

 Gly Cys Thr Phe Trp Gly Lys Lys Pro Trp Ser Arg Lys Lys Lys
                 350                 355                 360

 Ile Leu Trp Gln Leu Gly Thr Leu Val Gly Ala Pro Val Gly Ile
                 365                 370                 375

 Ala Leu Ile Ala Gly Ile Ala Ile Pro Ala Met Ile Ile Gly Ile
                 380                 385                 390

 Pro Val Tyr Val Gly Arg Lys Ile His Asn Arg Tyr Glu Gly Lys
                 395                 400                 405

 Asp Val Ser Lys His Lys Arg Asn Leu Ala Ile Ala Gly Gly Val
                 410                 415                 420

 Thr Leu Ser Val Ile Val Ser Pro Val Val Ala Ala Val Thr Val
                 425                 430                 435

 Gly Ile Gly Val Pro Ile Met Leu Ala Tyr Val Tyr Gly Val Val
                 440                 445                 450

 Pro Ile Ser Leu Cys Arg Ser Gly Gly Cys Gly Val Ser Ala Gly
                 455                 460                 465

 Asn Gly Lys Gly Val Arg Ile Glu Phe Asp Asp Glu Asn Asp Ile
                 470                 475                 480

 Asn Val Gly Gly Thr Asn Thr Ala Val Asp Thr Thr Ser Val Ala
                 485                 490                 495

 Glu Ala Arg His Asn Pro Ser Ile Gly Glu Gly Ser Val Gly Gly
                 500                 505                 510

 Leu Thr Gly Ser Leu Ser Ala Ser Gly Ser His Met Asp Arg Ile
                 515                 520                 525

 Gly Ala Ile Arg Asp Asn Leu Ser Glu Thr Ala Ser Thr Met Ala
                 530                 535                 540

 Leu Ala Gly Ala Ser Ile Thr Gly Ser Leu Ser Gly Ser Ala Met
                 545                 550                 555

 Val Asn Cys Phe Asn Arg Leu Glu Val Gln Ala Asp Val Gln Lys
                 560                 565                 570

 Glu Arg Tyr Ser Leu Ser Gly Glu Ser Gly Thr Val Ser Leu Gly
                 575                 580                 585

 Thr Val Ser Asp Asn Ala Ser Thr Lys Ala Met Ala Gly Ser Ile
                 590                 595                 600

 Leu Asn Ser Tyr Ile Pro Leu Asp Lys Glu Gly Asn Ser Met Glu
                 605                 610                 615

 Val Gln Val Asp Ile Glu Ser Lys Pro Ser Lys Phe Arg His Asn
                 620                 625                 630

 Ser Gly Ser Ser Ser Val Asp Asp Gly Ser Ala Thr Arg Ser Tyr
                 635                 640                 645

 Ala Gly Gly Ser Ser Ser Gly Leu Pro Glu Gly Lys Ser Ser Ala
                 650                 655                 660

 Thr Lys Trp Ser Lys Glu Ala Thr Ala Gly Lys Lys Ser Lys Ser
                 665                 670                 675

 Gly Lys Leu Arg Lys Lys Gly Asn Met Lys Ile Asn Glu Thr Arg
                 680                 685                 690

 Glu Asp Met Asp Ala Gln Leu Leu Glu Gln Gln Ser Thr Asn Ser
                 695                 700                 705

 Ser Glu Phe Glu Ala Pro Ser Leu Ser Asp Ser Met Pro Ser Val
                 710                 715                 720

 Ala Asp Ser His Ser Ser His Phe Ser Glu Phe Ser Cys Ser Asp
                 725                 730                 735

 Leu Glu Ser Met Lys Thr Ser Cys Ser His Gly Ser Ser Asp Tyr
                 740                 745                 750

 His Thr Arg Phe Ala Thr Val Asn Ile Leu Pro Glu Val Glu Asn
                 755                 760                 765

 Asp Arg Leu Glu Asn Ser Pro His Gln Cys Ser Ile Ser Val Val
                 770                 775                 780

 Thr Gln Thr Ala Ser Cys Ser Glu Val Ser Gln Leu Asn His Ile
                 785                 790                 795

 Ala Glu Glu His Gly Asn Asn Gly Ile Lys Pro Asn Val Asp Leu
                 800                 805                 810

 Tyr Phe Gly Asp Ala Leu Lys Glu Thr Asn Asn Asn His Ser His
                 815                 820                 825

 Gln Thr Met Glu Leu Lys Val Ala Ile Gln Thr Glu Ile
                 830                 835

<210> 6266
<211> 2665
<212> DNA
<213> Homo sapien

<400> 6266
 ggctctgggc atcaccagcg gccccaggga aaaagaaaga aatgggaaac 50

 agcatgaaat ccacccctgc gcctgccgag aggcccctgc ccaacccgga 100

 gggactggat agcgacttcc ttgccgtgct aagtgactac ccgtctcctg 150

 acatcagccc cccgatattc cgccgagggg agaaactgcg tgtgatttct 200

 gatgaagggg gctggtggaa agctatttct cttagcactg gtcgagagag 250

 ttacatccct ggaatatgtg tggccagagt ttaccatggc tggctgtttg 300

 agggcctggg cagagacaag gccgaggagc tgctgcagct gccagacaca 350

 aaggtcggct ccttcatgat cagagagagt gagaccaaga aagggtttta 400

 ctcactgtcg gtgagacaca ggcaggtaaa gcattaccgc attttccgtc 450

 tgccgaacaa ctggtactac atttccccga ggctcacctt ccagtgcctg 500

 gaggacctgg tgaaccacta ttctgaggtg gctgatggcc tgtgctgtgt 550

 gctcaccacg ccctgcctga cacaaagcac ggctgcccca gcagtgaggg 600

 cctccagctc acctgtcacc ttgcgtcaga agactgtgga ctggaggaga 650

 gtgtccagac tgcaggagga ccccgaggga acagagaacc cgcttggggt 700

 agacgagtcc cttttcagct atggccttcg agagagcatt gcctcttacc 750

 tgtccctgac cagtgaggac aacacctcct ttgatcgaaa gaagaaaagc 800

 atctccctga tgtatggtgg cagcaagaga aagagctcat tcttctcatc 850

 accaccttac tttgaggact agccaagaac agacacaatg gttcatgccc 900

 aaaaggaaca gaagttccaa ctattgcctg ggatcttgcg aaaagcgagg 950

 ttccctgatc cctgggagcc tcacgtattt tagaagccaa gagaagccac 1000

 atggagactc aaattcgcat cttctctatc cacatcatga ccaaaggaac 1050

 ccctccctgg tgtctgatca gggctgtggc atcacaaaac attggatcat 1100

 gacatgtcgg gcgatgcttg gaaaagccca gcatgtatgt atgcacacat 1150

 tgtgtgtgtg ggaaggacaa agccactctc acaagaaagg gcaccaggac 1200

 tgctctccaa ggaactggac ctgtccagac agttacactc caaggtcatt 1250

 ggagagaact tctgtatggg caagcctgag agggagagga aacaaaagct 1300

 gtgtcctggc agaaggtctg ggtttgcaga tgggtgccct gaatggaact 1350

 actttaacta atccataggg acttctggta tgctttcctc tctttttaaa 1400

 ggaacttcgt gacactaaac attagcccaa aggacttctt agccttcaat 1450

 tgggagatac ctttggtctg ctcctgcacc aaagccatat gggtggaagt 1500

 cagttggcct ccctggttct gcagagggcc agaagaatga gagagaggaa 1550

 gactgctggc agggaaatcg aggaggcgag actagaactg caccagcttc 1600

 cctgatgtct gcagccatgg ctttgcagcg caaacagaac ttctctggga 1650

 tgctgggatt cttgcctgta tgaatgcatc aagtattcat ttattgcccg 1700

 aataggcatt gcattaagtc ctctgttagg tgtcaggcaa gccaaaaaaa 1750

 aaaaaaagat gctaagtcct aacccccaac agaagtgttc acagtgtaga 1800

 cgggaaaaaa tgtataaaca aatgtgtaaa aagagaaatc agctcatggc 1850

 ttaggatgga attagagaca ggtgagggac actcaggagc tcattttcca 1900

 gctgctcttc agagtggaag ggctggctgg atcgggtagg taagaatagc 1950

 tggatttttt agaaaagaaa tggatacagt ctaaagaatt aactcacccg 2000

 gtactttatt ctaagaaggg tctggcatcc atatgaggaa aaatgctcag 2050

 ctccaggaaa gatggggagt ccaagtggat taatgatgtc atgcataatt 2100

 ttaagagaca agggagaaaa cacaatgtat agccagagaa ggagaagctc 2150

 ccatccaaat cctactagga agagagtggg ctgcagatga atctgtgact 2200

 catgtttccc tgtttcaaag ggatcctggg gaaggagggg aacatgcttg 2250

 cagtatctct ccctgtctgt ctgctcacat aagcattccg tccatctaag 2300

 ctcatcgtgc tactggtatg tgtatgtgca gttacacagt ttcctgtatc 2350

 ataaatccta gtgtgtttat acaaggagac atctgtggtt tccccaaccg 2400

 ttccaaaagg ctatttcaaa ggaaccagcc cacgtatgag aaatgaatgt 2450

 aacactgtgg acattgactt cccgcataag gcagggtgac cccctgaact 2500

 ccagatgttt gcacagtatc ttatgtgttg ttttccgttg tgacgaatgt 2550

 gattggaaca tttggggagc acccagaggg atttttcagt gggaagcatt 2600

 acactttgct aaatcatgta tttattcctg attaaaacaa acctaataaa 2650

 tatttaaccc ttggc 2665

<210> 6267
<211> 276
<212> PRT
<213> Homo sapien

<400> 6267
 Met Gly Asn Ser Met Lys Ser Thr Pro Ala Pro Ala Glu Arg Pro
   1               5                  10                  15

 Leu Pro Asn Pro Glu Gly Leu Asp Ser Asp Phe Leu Ala Val Leu
                  20                  25                  30

 Ser Asp Tyr Pro Ser Pro Asp Ile Ser Pro Pro Ile Phe Arg Arg
                  35                  40                  45

 Gly Glu Lys Leu Arg Val Ile Ser Asp Glu Gly Gly Trp Trp Lys
                  50                  55                  60

 Ala Ile Ser Leu Ser Thr Gly Arg Glu Ser Tyr Ile Pro Gly Ile
                  65                  70                  75

 Cys Val Ala Arg Val Tyr His Gly Trp Leu Phe Glu Gly Leu Gly
                  80                  85                  90

 Arg Asp Lys Ala Glu Glu Leu Leu Gln Leu Pro Asp Thr Lys Val
                  95                 100                 105

 Gly Ser Phe Met Ile Arg Glu Ser Glu Thr Lys Lys Gly Phe Tyr
                 110                 115                 120

 Ser Leu Ser Val Arg His Arg Gln Val Lys His Tyr Arg Ile Phe
                 125                 130                 135

 Arg Leu Pro Asn Asn Trp Tyr Tyr Ile Ser Pro Arg Leu Thr Phe
                 140                 145                 150

 Gln Cys Leu Glu Asp Leu Val Asn His Tyr Ser Glu Val Ala Asp
                 155                 160                 165

 Gly Leu Cys Cys Val Leu Thr Thr Pro Cys Leu Thr Gln Ser Thr
                 170                 175                 180

 Ala Ala Pro Ala Val Arg Ala Ser Ser Ser Pro Val Thr Leu Arg
                 185                 190                 195

 Gln Lys Thr Val Asp Trp Arg Arg Val Ser Arg Leu Gln Glu Asp
                 200                 205                 210

 Pro Glu Gly Thr Glu Asn Pro Leu Gly Val Asp Glu Ser Leu Phe
                 215                 220                 225

 Ser Tyr Gly Leu Arg Glu Ser Ile Ala Ser Tyr Leu Ser Leu Thr
                 230                 235                 240

 Ser Glu Asp Asn Thr Ser Phe Asp Arg Lys Lys Lys Ser Ile Ser
                 245                 250                 255

 Leu Met Tyr Gly Gly Ser Lys Arg Lys Ser Ser Phe Phe Ser Ser
                 260                 265                 270

 Pro Pro Tyr Phe Glu Asp
                 275

<210> 6268
<211> 1467
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 11, 26, 39, 44, 55, 57, 93, 97, 103, 133, 185
<223> Unknown base

<400> 6268
 cgtgaaatga ncggttcggt cgacantgct gtcttctcnt aacnagcttt 50

 gtaantnttc ttggaggagc ttgcctgggg gtgggatgcc acngagngcc 100

 ttnagtgttt ccccatgttc ctggagtgtt ttngcccttc ccttgtggga 150

 tggacagata gaggcacccg acttctacca ctaanactta gagcttctat 200

 tgatggtggg tggagaggat gtgtaggatg gtgatctgaa tgtttccact 250

 tccaaaagta gaccactagg gtgtcactga aaaggtttac agaactttgt 300

 gtcacatgca gcatttaacc caaaatatcc ttacaggtcc tgaaaaaggc 350

 ttgcttgact gtggaccttt accagatttc cttctgggag agtcatagct 400

 ttgttagtgg atggtatctg tgagctttca ttctctttct ttctaggaca 450

 gtgataccac caagaagaag aagaagaaga agaaagcaaa agaggtagaa 500

 ttggtttctg agtagtgaag gccacttgaa gctggaggag aaactaaagc 550

 cttattgaga aaacatgtta tagatccttt tgttgctgag agagtggaac 600

 ataggtccta gacagggtga agagttctgg cacattttag ctgctacttt 650

 gagacctcgg tgatgttacc tggtgtggtc atcccatctt gtcctgtttt 700

 aaggatatgg gtggtgaaag atgaaagagg cagagtttat cccaatgact 750

 tctctgtttg agttgggaag cctcaccttc agacccagta actgtccgca 800

 gctgtctgct agtggttgtc ttaacatcgt agtcctagtt tgcatttttt 850

 aaatcccctc tgtttaaaag gtttgtaaaa caaaaacaaa aaactaagtc 900

 tgctcagtga aatgctgtag aaccctaaat aagtggtaga agagtgtcac 950

 tgaattttgt ctctgaattc agtataactg agttttgtcc atgctggtgt 1000

 ctgggttata ggcctgatgg gcctggtagt tttccatctt gttctggcct 1050

 agaggtcagt cctttgcact tcctcaaagc ttgtgtacag tgctcaccta 1100

 aatccatctg actacttgtt cctgtgccct cttgttttag gcctcgttta 1150

 cttttaaaaa atgaaattgt tcattgctgg gagaagaatg ttgtaatttt 1200

 tacttattaa agtcaacttg ttaagttttt tatgtattcc tgttgggttt 1250

 tcttgttgat ctcatgctag cagagcaaaa attgtaaaat attttgatta 1300

 aaaatctagg gacctttatg tcctatttga aatgtgatgc tttatgttgt 1350

 ttctggtttt acattttgtc tgtatcctac acaatcactt gggccctgtc 1400

 atctgatgtg agatcaagta ctcagaggca gtgattacca caaaaccact 1450

 gatctctaga agaacaa 1467

<210> 6269
<211> 6550
<212> DNA
<213> Homo sapien

<400> 6269
 tcccggaagg caaatggctg gcgtggaagc acaacccgct ttcactcttc 50

 gaatttgtgc ttagctcttt tcttgtacct tgcgactcgt gaccaacatg 100

 ctgtgatgtg tgccgaggga ggaattggtc agctacacaa cctggatctt 150

 accacagttt ggatatgact gaggctctcc aatgggccag atatcactgg 200

 cgacggctga tcagaggtgc aaccagggat gatgattcag ggccatacaa 250

 ctattcctcg ttgctcgcct gtgggcgcaa gtcctctcag acccctaaac 300

 tgtcaggaag gcaccggatt gttgttcccc acatccagcc cttcaaggat 350

 gagtatgaga agttctccgg agcctatgtg aacaatcgaa tacgaacaac 400

 aaagtacaca cttctgaatt ttgtgccaag aaatttattt gaacaatttc 450

 acagagctgc caatttatat ttcctgttcc tagttgtcct gaactgggta 500

 cctttggtag aagccttcca aaaggaaatc accatgttgc ctctggtggt 550

 ggtccttaca attatcgcaa ttaaagatgg cctggaaggt tatcggaaat 600

 acaaaattga caaacagatc aataatttaa taactaaagt ttatagtagg 650

 aaagagaaaa aatacattga ccgatgctgg aaagacgtta ctgttgggga 700

 ctttattcgc ctctcctgca acgaggtcat ccctgcagac atggtactac 750

 tcttttccac tgatccagat ggaatctgtc acattgagac ttctggtctt 800

 gatggagaga gcaatttaaa acagaggcag gtggttcggg gatatgcaga 850

 acaggactct gaagttgatc ctgagaagtt ttccagtagg atagaatgtg 900

 aaagcccaaa caatgacctc agcagattcc gaggcttcct agaacattcc 950

 aacaaagaac gcgtgggtct cagtaaagaa aatttgttgc ttagaggatg 1000

 caccattaga aacacagagg ctgttgtggg cattgtggtt tatgcaggcc 1050

 atgaaaccaa agcaatgctg aacaacagtg ggccacggta taagcgcagc 1100

 aaattagaaa gaagagcaaa cacagatgtc ctctggtgtg tcatgcttct 1150

 ggtcataatg tgcttaactg gcgcagtagg tcatggaatc tggctgagca 1200

 ggtatgaaaa gatgcatttt ttcaatgttc ccgagcctga tggacatatc 1250

 atatcaccac tgttggcagg attttatatg ttttggacca tgatcatttt 1300

 gttacaggtc ttgattccta tttctctcta tgtttccatc gaaattgtga 1350

 agcttggaca aatatatttc attcaaagtg atgtggattt ctacaatgaa 1400

 aaaatggatt ctattgttca gtgccgagcc ctgaacatcg ccgaggatct 1450

 gggacagatt cagtacctct tttccgataa gacaggaacc ctcactgaga 1500

 ataagatggt ttttcgaaga tgtagtgtgg caggatttga ttactgccat 1550

 gaagaaaatg ccaggaggtt ggagtcctat caggaagctg tctctgaaga 1600

 tgaagatttt atagacacag tcagtggttc cctcagcaat atggcaaaac 1650

 cgagagcccc cagctgcagg acagttcata atgggccttt gggaaataag 1700

 ccctcaaatc atcttgctgg gagctctttt actctaggaa gtggagaagg 1750

 agccagtgaa gtgcctcatt ccagacaggc tgctttcagt agccccattg 1800

 aaacagacgt ggtaccagac accaggcttt tagacaaatt tagtcagatt 1850

 acacctcggc tctttatgcc actagatgag accatccaaa atccaccaat 1900

 ggaaactttg tacattatcg actttttcat tgcattggca atttgcaaca 1950

 cagtagtggt ttctgctcct aaccaacccc gacaaaagat cagacaccct 2000

 tcactggggg ggttgcccat taagtctttg gaagagatta aaagtctttt 2050

 ccagagatgg tctgtccgaa gatcaagttc tccatcgctt aacagtggga 2100

 aagagccatc ttctggagtt ccaaacgcct ttgtgagcag actccctctc 2150

 tttagtcgaa tgaaaccagc ttcacctgtg gaggaagagg tctcccaggt 2200

 gtgtgagagc ccccagtgct ccagtagctc agcttgctgc acagaaacag 2250

 agaaacaaca cggtgatgca ggcctcctga atggcaaggc agagtccctc 2300

 cctggacagc cattggcctg caacctgtgt tatgaggccg agagcccaga 2350

 cgaagcggcc ttagtgtatg ccgccagggc ttaccaatgc actttacggt 2400

 ctcggacacc agagcaggtc atggtggact ttgctgcttt gggaccatta 2450

 acatttcaac tcctacacat cctgcccttt gactcagtaa gaaaaagaat 2500

 gtctgttgtg gtccgacacc ctctttccaa tcaagttgtg gtgtatacga 2550

 aaggcgctga ttctgtgatc atggagttac tgtcggtggc ttccccagat 2600

 ggagcaagtc tggagaaaca acagatgata gtaagggaga aaacccagaa 2650

 gcacttggat gactatgcca aacaaggcct tcgtacttta tgtatagcaa 2700

 agaaggtcat gagtgacact gaatatgcag agtggctgag gaatcatttt 2750

 ttagctgaaa ccagcattga caacagggaa gaattactac ttgaatctgc 2800

 catgaggttg gagaacaaac ttacattact tggtgctact ggcattgaag 2850

 accgtctgca ggagggagtc cctgaatcta tagaagctct tcacaaagcg 2900

 ggcatcaaga tctggatgct gacaggggac aagcaggaga cagctgtcaa 2950

 catagcttat gcatgcaaac tactggagcc agatgacaag ctttttatcc 3000

 tcaataccca aagtaaagat gcctgtggga tgctgatgag cacaattttg 3050

 aaagaacttc agaagaaaac tcaagccctg ccagagcaag tgtcattaag 3100

 tgaagattta cttcagcctc ctgtcccccg ggactcaggg ttacgagctg 3150

 gactcattat cactgggagg accctggagt ttgccctgca agaaagtctg 3200

 caaaagcagt tcctggaact gacatcttgg tgtcaagctg tggtctgctg 3250

 ccgagccaca ccgctgcaga aaagtgaagt ggtgaaattg gtccgcagcc 3300

 atctccaggt gatgaccctt gctattggtg atggtgccaa tgatgttagc 3350

 atgatacaag tggcagacat tgggataggg gtctcaggtc aagaaggcat 3400

 gcaggctgtg atggccagtg actttgccgt ttatcagttc aaacatctca 3450

 gcaagctcct tcttgtccat ggacactggt gttatacacg gctttccaac 3500

 atgattctct attttttcta taagaatgtg gcctatgtga acctcctttt 3550

 ctggtaccag ttcttttgtg gattttcagg gacatccatg actgattact 3600

 gggttttgat cttcttcaac ctcctcttca catctgcccc tcctgtcatt 3650

 tatggtgttt tggagaaaga tgtgtctgca gagaccctca tgcaactgcc 3700

 tgaactttac agaagtggtc agaaatcaga ggcatactta ccccatacct 3750

 tctggatcac cttattggat gctttttatc aaagcctggt ctgcttcttt 3800

 gtgccttatt ttacctacca gggctcagat actgacatct ttgcatttgg 3850

 aaaccccctg aacacagccg ctctgttcat cgttctcctc catctggtca 3900

 ttgaaagcaa gagtttgact tggattcact tgctggtcat cattggtagc 3950

 atcttgtctt attttttatt tgccatagtt tttggagcca tgtgtgtaac 4000

 ttgcaaccca ccatccaacc cttactggat tatgcaggag cacatgctgg 4050

 atccagtatt ctacttagtt tgtatcctca cgacgtccat tgctcttctg 4100

 cccaggtttg tatacagagt tcttcaggga tccctgtttc catctccaat 4150

 tctgagagct aagcactttg acagactaac tccagaggag aggactaaag 4200

 ctctcaagaa gtggagaggg gctggaaaga tgaatcaagt gacatcaaag 4250

 tatgctaacc aatcagctgg caagtcagga agaagaccca tgcctggccc 4300

 ttctgctgta tttgcaatga agtcagcaag ttcctgtgct attgagcaag 4350

 gaaacttatc tctgtgtgag actgctttag atcaaggcta ctctgaaact 4400

 aaggcctttg agatggctgg accctccaaa ggtaaagaaa gctagatacc 4450

 ctccttggag ttgcaagtat tctttcaagg ttggaagagg gattttgaag 4500

 aggtatctct ccaagcaaga atgacttgtt tttccataag ggacatgagc 4550

 attttactag gcttggaaga gctgacatga tgagcattat tgtatgtttg 4600

 tatatacatt tgtgatagag ggctagagtt tgacctagag agagtttaag 4650

 gaagtgaaat atttaattca gaaccaaatg cttttgtaaa actttttgga 4700

 ttttgtaaaa gcattttcat tctcttagaa attcaagtat tttcaagggg 4750

 agtcatttga gatatattta ttttactagg agatcttata ttctagggaa 4800

 atgctttaaa tggtcaggct ccagtcggaa tttttttaag aaaaaagtag 4850

 tttttaatac attggttagg actcagagga aatacggaaa aaacattgta 4900

 gatggttaat ttacagataa aatcccaaga gccttttaaa caacaaggta 4950

 cctaaaatag ggtataatta tactgcttaa aatacagtta gtgcctatta 5000

 atagcttttt atttcctatg ggaagatgct tttggtcttc tggctgaaga 5050

 tgtaggcata cctctcactc atttcaatgt tttcctgagg tggagccttc 5100

 attggaaagg ggaaagaggg attctagggt ttcatcaggg accaggaatg 5150

 cattcctctg tcaggttcca atcaagagaa gaccttttat gagatctgcc 5200

 tctgtataga tgttgtcagt taggaaactg aagccatagg tcaggcagac 5250

 atcagctcag cctgtggccc attgggtgat ttcctgtatt ttaaaactga 5300

 cagtagcctg atcaaagtga tacaatcaat ttcaaaacaa tcttccagag 5350

 accacttgaa ggttcatagt ttttacaata ccctgagact tttcaggtgt 5400

 tggagcctct aaaatatgag atataaacag aaactaatac aagttgttct 5450

 ctggaggttt ctatgaggtt cttagaaaaa tttggtttta aaatcatttg 5500

 aggacaggaa tgtctatagc aagtttactc ctattgcgaa tcatgtatgc 5550

 tggctttagt tgtaacaaac gattttattc taagtaaggc caggtgctac 5600

 tataaaatca tatattcctg ttgaagttct tttgaagtcc tatctctatt 5650

 tattatattt gaaagttgtc agccaccagt catccagaat ttccttcctg 5700

 aatctccatg ctcatatgca atgtctacat caaggtcttc ttaatgacta 5750

 ttattctcag ggtttagttt tctaccttct gcctactatt ttggtctgac 5800

 atttttgtag ccttctgtta ttattggaaa tagtctctta cataagctga 5850

 tttcgagaac tttcaaaatc tcacatagct aatggaagtt gctttctgct 5900

 ttcttatgac tgtttttata aataaactgt ttcataaata atgtatactg 5950

 gaaaattgtc atcactcttg taaacatttg ccaaatccaa ctgtaattag 6000

 taccagaact tagaaggaaa gtcacaaagc atgcctttta ccagaatatt 6050

 gctttgcctt ttcttatatg gaaaatcact gatgtcatat catttattat 6100

 cctcacagca gctggcattc attccctgaa atcgtcgtct cctgataaac 6150

 aataatttag agatatgttc acttgtaaat aaaaaggtta gaatctaagg 6200

 acaaagaatg atccaaaaat actaaggaaa aagaacaatt ttcaattttc 6250

 agaaatgaat tatctgtaca tatgaataga ggaaaatact gagtgctaat 6300

 gttacagggc cacaatctca tatccacaat tccaaaatct ccaaacctct 6350

 gaaaactgaa atatttttca taaattaggc gtaaattcta tgccctgaac 6400

 aaatgtaaag ctatttatgt actttgctta atgtaatcat tcatatactt 6450

 tgctacaaaa atattaatat atttcattac tgaatgctaa actgtatttc 6500

 tttttaaaat ttggaaaatt tttaattctg aaacacaatc tagaccttag 6550

<210> 6270
<211> 1426
<212> PRT
<213> Homo sapien

<400> 6270
 Met Thr Glu Ala Leu Gln Trp Ala Arg Tyr His Trp Arg Arg Leu
   1               5                  10                  15

 Ile Arg Gly Ala Thr Arg Asp Asp Asp Ser Gly Pro Tyr Asn Tyr
                  20                  25                  30

 Ser Ser Leu Leu Ala Cys Gly Arg Lys Ser Ser Gln Thr Pro Lys
                  35                  40                  45

 Leu Ser Gly Arg His Arg Ile Val Val Pro His Ile Gln Pro Phe
                  50                  55                  60

 Lys Asp Glu Tyr Glu Lys Phe Ser Gly Ala Tyr Val Asn Asn Arg
                  65                  70                  75

 Ile Arg Thr Thr Lys Tyr Thr Leu Leu Asn Phe Val Pro Arg Asn
                  80                  85                  90

 Leu Phe Glu Gln Phe His Arg Ala Ala Asn Leu Tyr Phe Leu Phe
                  95                 100                 105

 Leu Val Val Leu Asn Trp Val Pro Leu Val Glu Ala Phe Gln Lys
                 110                 115                 120

 Glu Ile Thr Met Leu Pro Leu Val Val Val Leu Thr Ile Ile Ala
                 125                 130                 135

 Ile Lys Asp Gly Leu Glu Gly Tyr Arg Lys Tyr Lys Ile Asp Lys
                 140                 145                 150

 Gln Ile Asn Asn Leu Ile Thr Lys Val Tyr Ser Arg Lys Glu Lys
                 155                 160                 165

 Lys Tyr Ile Asp Arg Cys Trp Lys Asp Val Thr Val Gly Asp Phe
                 170                 175                 180

 Ile Arg Leu Ser Cys Asn Glu Val Ile Pro Ala Asp Met Val Leu
                 185                 190                 195

 Leu Phe Ser Thr Asp Pro Asp Gly Ile Cys His Ile Glu Thr Ser
                 200                 205                 210

 Gly Leu Asp Gly Glu Ser Asn Leu Lys Gln Arg Gln Val Val Arg
                 215                 220                 225

 Gly Tyr Ala Glu Gln Asp Ser Glu Val Asp Pro Glu Lys Phe Ser
                 230                 235                 240

 Ser Arg Ile Glu Cys Glu Ser Pro Asn Asn Asp Leu Ser Arg Phe
                 245                 250                 255

 Arg Gly Phe Leu Glu His Ser Asn Lys Glu Arg Val Gly Leu Ser
                 260                 265                 270

 Lys Glu Asn Leu Leu Leu Arg Gly Cys Thr Ile Arg Asn Thr Glu
                 275                 280                 285

 Ala Val Val Gly Ile Val Val Tyr Ala Gly His Glu Thr Lys Ala
                 290                 295                 300

 Met Leu Asn Asn Ser Gly Pro Arg Tyr Lys Arg Ser Lys Leu Glu
                 305                 310                 315

 Arg Arg Ala Asn Thr Asp Val Leu Trp Cys Val Met Leu Leu Val
                 320                 325                 330

 Ile Met Cys Leu Thr Gly Ala Val Gly His Gly Ile Trp Leu Ser
                 335                 340                 345

 Arg Tyr Glu Lys Met His Phe Phe Asn Val Pro Glu Pro Asp Gly
                 350                 355                 360

 His Ile Ile Ser Pro Leu Leu Ala Gly Phe Tyr Met Phe Trp Thr
                 365                 370                 375

 Met Ile Ile Leu Leu Gln Val Leu Ile Pro Ile Ser Leu Tyr Val
                 380                 385                 390

 Ser Ile Glu Ile Val Lys Leu Gly Gln Ile Tyr Phe Ile Gln Ser
                 395                 400                 405

 Asp Val Asp Phe Tyr Asn Glu Lys Met Asp Ser Ile Val Gln Cys
                 410                 415                 420

 Arg Ala Leu Asn Ile Ala Glu Asp Leu Gly Gln Ile Gln Tyr Leu
                 425                 430                 435

 Phe Ser Asp Lys Thr Gly Thr Leu Thr Glu Asn Lys Met Val Phe
                 440                 445                 450

 Arg Arg Cys Ser Val Ala Gly Phe Asp Tyr Cys His Glu Glu Asn
                 455                 460                 465

 Ala Arg Arg Leu Glu Ser Tyr Gln Glu Ala Val Ser Glu Asp Glu
                 470                 475                 480

 Asp Phe Ile Asp Thr Val Ser Gly Ser Leu Ser Asn Met Ala Lys
                 485                 490                 495

 Pro Arg Ala Pro Ser Cys Arg Thr Val His Asn Gly Pro Leu Gly
                 500                 505                 510

 Asn Lys Pro Ser Asn His Leu Ala Gly Ser Ser Phe Thr Leu Gly
                 515                 520                 525

 Ser Gly Glu Gly Ala Ser Glu Val Pro His Ser Arg Gln Ala Ala
                 530                 535                 540

 Phe Ser Ser Pro Ile Glu Thr Asp Val Val Pro Asp Thr Arg Leu
                 545                 550                 555

 Leu Asp Lys Phe Ser Gln Ile Thr Pro Arg Leu Phe Met Pro Leu
                 560                 565                 570

 Asp Glu Thr Ile Gln Asn Pro Pro Met Glu Thr Leu Tyr Ile Ile
                 575                 580                 585

 Asp Phe Phe Ile Ala Leu Ala Ile Cys Asn Thr Val Val Val Ser
                 590                 595                 600

 Ala Pro Asn Gln Pro Arg Gln Lys Ile Arg His Pro Ser Leu Gly
                 605                 610                 615

 Gly Leu Pro Ile Lys Ser Leu Glu Glu Ile Lys Ser Leu Phe Gln
                 620                 625                 630

 Arg Trp Ser Val Arg Arg Ser Ser Ser Pro Ser Leu Asn Ser Gly
                 635                 640                 645

 Lys Glu Pro Ser Ser Gly Val Pro Asn Ala Phe Val Ser Arg Leu
                 650                 655                 660

 Pro Leu Phe Ser Arg Met Lys Pro Ala Ser Pro Val Glu Glu Glu
                 665                 670                 675

 Val Ser Gln Val Cys Glu Ser Pro Gln Cys Ser Ser Ser Ser Ala
                 680                 685                 690

 Cys Cys Thr Glu Thr Glu Lys Gln His Gly Asp Ala Gly Leu Leu
                 695                 700                 705

 Asn Gly Lys Ala Glu Ser Leu Pro Gly Gln Pro Leu Ala Cys Asn
                 710                 715                 720

 Leu Cys Tyr Glu Ala Glu Ser Pro Asp Glu Ala Ala Leu Val Tyr
                 725                 730                 735

 Ala Ala Arg Ala Tyr Gln Cys Thr Leu Arg Ser Arg Thr Pro Glu
                 740                 745                 750

 Gln Val Met Val Asp Phe Ala Ala Leu Gly Pro Leu Thr Phe Gln
                 755                 760                 765

 Leu Leu His Ile Leu Pro Phe Asp Ser Val Arg Lys Arg Met Ser
                 770                 775                 780

 Val Val Val Arg His Pro Leu Ser Asn Gln Val Val Val Tyr Thr
                 785                 790                 795

 Lys Gly Ala Asp Ser Val Ile Met Glu Leu Leu Ser Val Ala Ser
                 800                 805                 810

 Pro Asp Gly Ala Ser Leu Glu Lys Gln Gln Met Ile Val Arg Glu
                 815                 820                 825

 Lys Thr Gln Lys His Leu Asp Asp Tyr Ala Lys Gln Gly Leu Arg
                 830                 835                 840

 Thr Leu Cys Ile Ala Lys Lys Val Met Ser Asp Thr Glu Tyr Ala
                 845                 850                 855

 Glu Trp Leu Arg Asn His Phe Leu Ala Glu Thr Ser Ile Asp Asn
                 860                 865                 870

 Arg Glu Glu Leu Leu Leu Glu Ser Ala Met Arg Leu Glu Asn Lys
                 875                 880                 885

 Leu Thr Leu Leu Gly Ala Thr Gly Ile Glu Asp Arg Leu Gln Glu
                 890                 895                 900

 Gly Val Pro Glu Ser Ile Glu Ala Leu His Lys Ala Gly Ile Lys
                 905                 910                 915

 Ile Trp Met Leu Thr Gly Asp Lys Gln Glu Thr Ala Val Asn Ile
                 920                 925                 930

 Ala Tyr Ala Cys Lys Leu Leu Glu Pro Asp Asp Lys Leu Phe Ile
                 935                 940                 945

 Leu Asn Thr Gln Ser Lys Asp Ala Cys Gly Met Leu Met Ser Thr
                 950                 955                 960

 Ile Leu Lys Glu Leu Gln Lys Lys Thr Gln Ala Leu Pro Glu Gln
                 965                 970                 975

 Val Ser Leu Ser Glu Asp Leu Leu Gln Pro Pro Val Pro Arg Asp
                 980                 985                 990

 Ser Gly Leu Arg Ala Gly Leu Ile Ile Thr Gly Arg Thr Leu Glu
                 995                1000                1005

 Phe Ala Leu Gln Glu Ser Leu Gln Lys Gln Phe Leu Glu Leu Thr
                1010                1015                1020

 Ser Trp Cys Gln Ala Val Val Cys Cys Arg Ala Thr Pro Leu Gln
                1025                1030                1035

 Lys Ser Glu Val Val Lys Leu Val Arg Ser His Leu Gln Val Met
                1040                1045                1050

 Thr Leu Ala Ile Gly Asp Gly Ala Asn Asp Val Ser Met Ile Gln
                1055                1060                1065

 Val Ala Asp Ile Gly Ile Gly Val Ser Gly Gln Glu Gly Met Gln
                1070                1075                1080

 Ala Val Met Ala Ser Asp Phe Ala Val Tyr Gln Phe Lys His Leu
                1085                1090                1095

 Ser Lys Leu Leu Leu Val His Gly His Trp Cys Tyr Thr Arg Leu
                1100                1105                1110

 Ser Asn Met Ile Leu Tyr Phe Phe Tyr Lys Asn Val Ala Tyr Val
                1115                1120                1125

 Asn Leu Leu Phe Trp Tyr Gln Phe Phe Cys Gly Phe Ser Gly Thr
                1130                1135                1140

 Ser Met Thr Asp Tyr Trp Val Leu Ile Phe Phe Asn Leu Leu Phe
                1145                1150                1155

 Thr Ser Ala Pro Pro Val Ile Tyr Gly Val Leu Glu Lys Asp Val
                1160                1165                1170

 Ser Ala Glu Thr Leu Met Gln Leu Pro Glu Leu Tyr Arg Ser Gly
                1175                1180                1185

 Gln Lys Ser Glu Ala Tyr Leu Pro His Thr Phe Trp Ile Thr Leu
                1190                1195                1200

 Leu Asp Ala Phe Tyr Gln Ser Leu Val Cys Phe Phe Val Pro Tyr
                1205                1210                1215

 Phe Thr Tyr Gln Gly Ser Asp Thr Asp Ile Phe Ala Phe Gly Asn
                1220                1225                1230

 Pro Leu Asn Thr Ala Ala Leu Phe Ile Val Leu Leu His Leu Val
                1235                1240                1245

 Ile Glu Ser Lys Ser Leu Thr Trp Ile His Leu Leu Val Ile Ile
                1250                1255                1260

 Gly Ser Ile Leu Ser Tyr Phe Leu Phe Ala Ile Val Phe Gly Ala
                1265                1270                1275

 Met Cys Val Thr Cys Asn Pro Pro Ser Asn Pro Tyr Trp Ile Met
                1280                1285                1290

 Gln Glu His Met Leu Asp Pro Val Phe Tyr Leu Val Cys Ile Leu
                1295                1300                1305

 Thr Thr Ser Ile Ala Leu Leu Pro Arg Phe Val Tyr Arg Val Leu
                1310                1315                1320

 Gln Gly Ser Leu Phe Pro Ser Pro Ile Leu Arg Ala Lys His Phe
                1325                1330                1335

 Asp Arg Leu Thr Pro Glu Glu Arg Thr Lys Ala Leu Lys Lys Trp
                1340                1345                1350

 Arg Gly Ala Gly Lys Met Asn Gln Val Thr Ser Lys Tyr Ala Asn
                1355                1360                1365

 Gln Ser Ala Gly Lys Ser Gly Arg Arg Pro Met Pro Gly Pro Ser
                1370                1375                1380

 Ala Val Phe Ala Met Lys Ser Ala Ser Ser Cys Ala Ile Glu Gln
                1385                1390                1395

 Gly Asn Leu Ser Leu Cys Glu Thr Ala Leu Asp Gln Gly Tyr Ser
                1400                1405                1410

 Glu Thr Lys Ala Phe Glu Met Ala Gly Pro Ser Lys Gly Lys Glu
                1415                1420                1425

 Ser


<210> 6271
<211> 5117
<212> DNA
<213> Homo sapien

<400> 6271
 aattcggcac gagggggggc agcagcggac gccgctaacg gcctccctcg 50

 gcgctgacag gctgggccgg cgcccggctc gcttgggtgt tcgcgtcgcc 100

 acttcggctt ctcggccggt cgggcccctc ggcccgggct tgcggcgcgc 150

 gtcggggctg agggctgctg cggcgcaggg agaggcctgg tcctcgctgc 200

 cgagggatgt gagtgggagc tgagcccaca ctggagggcc cccgagggcc 250

 cagcctggag gtcgttcaga gccgtgcccg ccccggggct tcgcagacct 300

 tgacccgccg ggtaggagcc gcccctgcgg gctcgagggc gcgctctggt 350

 cgcccgatct gtgtagccgg tttcagaagc aggcaacagg aacaagatgt 400

 gaactgtttc tcttctgcag aaaaagaggc tcttcctcct cctcccgcga 450

 cggcaaatgt tctgaaaaag actctgcatg ggaatggcct gccttacgat 500

 gacagaaatg gagggaacat ccacctcttc tatatatcag aatggtgata 550

 tttctggaaa tgccaattct atgaagcaaa tagatccagt tcttcaggtg 600

 tatctttacc attcccttgg gaaatctgag gcagattatc tgacctttcc 650

 atctggggag tatgttgcag aagaaatctg tattgctgct tctaaagctt 700

 gtggtatcac acctgtgtat cataatatgt ttgctttaat gagtgaaaca 750

 gaaaggatct ggtatccacc caaccatgtc ttccatatag atgagtcaac 800

 caggcataat gtactctaca gaataagatt ttactttcct cgttggtatt 850

 gcagtggcag caacagagcc tatcggcatg gaatatctcg aggtgctgaa 900

 gctcctcttc ttgatgactt tgtcatgtct tacctctttg ctcagtggcg 950

 gcatgatttt gtgcacggat ggataaaagt acctgtgact catgaaacac 1000

 aggaagaatg tcttgggatg gcagtgttag atatgatgag aatagccaaa 1050

 gaaaacgatc aaaccccact ggccatctat aactctatca gctacaagac 1100

 attcttacca aaatgtattc gagcaaagat ccaagactat catattttga 1150

 caaggaagcg aataaggtac agatttcgca gatttattca gcaattcagc 1200

 caatgcaaag ccactgccag aaacttgaaa cttaagtatc ttataaatct 1250

 ggaaactctg cagtctgcct tctacacaga gaaatttgaa gtaaaagaac 1300

 ctggaagtgg tccttcaggt gaggagattt ttgcaaccat tataataact 1350

 ggaaacggtg gaattcagtg gtcaagaggg aaacataaag aaagtgagac 1400

 actgacagaa caggatttac agttatattg cgatttttct aatattattg 1450

 atgtcagtat taagcaagca aaccaagagg gttcaaatga aagccgagtt 1500

 gtaactatcc ataagcaaga tggtaaaaat ctggaaattg aacttagctc 1550

 attaagggaa gctttgtctt tcgtgtcatt aattgatgga tattatagat 1600

 taactgcaga tgcacatcat tacctctgta aagaagtagc acctccagcc 1650

 gtgcttgaaa atatacaaag caactgtcat ggcccaattt cgatggattt 1700

 tgccattagt aaactgaaga aagcaggtaa tcagactgga ctgtatgtac 1750

 ttcgatgcag tcctaaggac tttaataaat attttttgac ttttgctgtc 1800

 gagcgagaaa atgtcattga atataaacac tgtttgatta caaaaaatga 1850

 gaatgaagag tacaacctca gtgggacaaa gaagaacttc agcagtctta 1900

 aagatctttt gaattgttac cagatggaaa ctgttcgctc agacaatata 1950

 attttccagt ttactaaatg ctgtccccca aagccaaaag ataaatcaaa 2000

 ccttctagtc ttcagaacga atggtgtttc tgatgtacca acctcaccaa 2050

 cattacagag gcctactcat atgaaccaaa tggtgtttca caaaatcaga 2100

 aatgaagatt tgatatttaa tgaaagcctt ggccaaggca cttttacaaa 2150

 gatttttaaa ggcgtacgaa gagaagtagg agactacggt caactgcatg 2200

 aaacagaagt tcttttaaaa gttctggata aagcacacag aaactattca 2250

 gagtctttct ttgaagcagc aagtatgatg agcaagcttt ctcacaagca 2300

 tttggtttta aattatggag tatgtgtctg tggagacgag aatattctgg 2350

 ttcaggagtt tgtaaaattt ggatcactag atacatatct gaaaaagaat 2400

 aaaaattgta taaatatatt atggaaactt gaagttgcta aacagttggc 2450

 atgggccatg cattttctag aagaaaacac ccttattcat gggaatgtat 2500

 gtgccaaaaa tattctgctt atcagagaag aagacaggaa gacaggaaat 2550

 cctcctttca tcaaacttag tgatcctggc attagtatta cagttttgcc 2600

 aaaggacatt cttcaggaga gaataccatg ggtaccacct gaatgcattg 2650

 aaaatcctaa aaatttaaat ttggcaacag acaaatggag ttttggtacc 2700

 actttgtggg aaatctgcag tggaggagat aaacctctaa gtgctctgga 2750

 ttctcaaaga aagctacaat tttatgaaga taggcatcag cttcctgcac 2800

 caaagtgggc agaattagca aaccttataa ataattgtat ggattatgaa 2850

 ccagatttca ggccttcttt cagagccatc atacgagatc ttaacagttt 2900

 gtttactcca gattatgaac tattaacaga aaatgacatg ttaccaaata 2950

 tgaggatagg tgccctgggg ttttctggtg cctttgaaga ccgggatcct 3000

 acacagtttg aagagagaca tttgaaattt ctacagcaac ttggcaaggg 3050

 taattttggg agtgtggaga tgtgccggta tgaccctcta caggacaaca 3100

 ctggggaggt ggtcgctgta aaaaagcttc agcatagtac tgaagagcac 3150

 ctaagagact ttgaaaggga aattgaaatc ctgaaatccc tacagcatga 3200

 caacattgta aagtacaagg gagtgtgcta cagtgctggt cggcgtaatc 3250

 taaaattaat tatggaatat ttaccatatg gaagtttacg agactatctt 3300

 caaaaacata aagaacggat agatcacata aaacttctgc agtacacatc 3350

 tcagatatgc aagggtatgg agtatcttgg tacaaaaagg tatatccaca 3400

 gggatctggc aacgagaaat atattggtgg agaacgagaa cagagttaaa 3450

 attggagatt ttgggttaac caaagtcttg ccacaagaca aagaatacta 3500

 taaagtaaaa gaacctggtg aaagtcccat attctggtat gctccagaat 3550

 cactgacaga gagcaagttt tctgtggcct cagatgtttg gagctttgga 3600

 gtggttctgt atgaactttt cacatacatt gagaagagta aaagtccacc 3650

 agcggaattt atgcgtatga ttggcaatga caaacaagga cagatgatcg 3700

 tgttccattt gatagaactt ttgaagaata atggaagatt accaagacca 3750

 gatggatgcc cagatgagat ctatatgatc atgacagaat gctggaacaa 3800

 taatgtaaat caacgcccct cctttaggga tctagctctt cgagtggatc 3850

 aaataaggga taacatggct ggatgaaaga aatgaccttc attctgagac 3900

 caaagtagat ttacagaaca aagttttata tttcacattg ctgtggacta 3950

 ttattacata tatcattatt atataaatca tgatgctagc cagcaaagat 4000

 gtgaaaatat ctgctcaaaa ctttcaaagt ttagtaagtt tttcttcatg 4050

 aggccaccag taaaagacat taatgagaat tccttagcaa ggattttgta 4100

 agaagtttct taaacattgt cagttaacat cactcttgtc tggcaaaaga 4150

 aaaaaaatag actttttcaa ctcagctttt tgagacctga aaaaattatt 4200

 atgtaaattt tgcaatgtta aagatgcaca gaatatgtat gtatagtttt 4250

 taccacagtg gatgtataat accttggcat cttgtgtgat gttttacaca 4300

 catgagggct ggtgttcatt aatactgttt tctaattttt ccatagttaa 4350

 tctataatta attacttcac tatacaaaca aattaagatg ttcagataat 4400

 tgaataagta cctttgtgtc cttgttcatt tatatcgctg gccagcatta 4450

 taagcaggtg tatactttta gcttgtagtt ccatgtactg taaatatttt 4500

 tcacataaag ggaacaaatg tctagtttta tttgtatagg aaatttccct 4550

 gaccctaaat aatacatttt gaaatgaaac aagcttacaa agatataatc 4600

 tattttatta tggtttccct tgtatctatt tgtggtgaat gtgtttttta 4650

 aatggaacta tctccaaatt tttctaagac tactatgaac agttttcttt 4700

 taaaattttg agattaagaa tgccaggaat attgtcatcc tttgagctgc 4750

 tgactgccaa taacattctt cgatctctgg gatttatgct catgaactaa 4800

 atttaagctt aagccataaa atagattaga ttgtttttta aaaatggata 4850

 gctcattaag aagtgcagca ggttaagaat tttttcctaa agactgtata 4900

 tttgaggggt ttcagaattt tgcattgcag tcatagaaga gatttatttc 4950

 ctttttagag gggaaatgag gtaaataagt aaaaaagtat gcttgttaat 5000

 tttattcaag aatgccagta gaaaattcat aacgtgtatc tttaagaaaa 5050

 atgagcatac atcttaaatc ttttcaatta aggtcgacgc ggccgcggtc 5100

 gacgcggccg cgaattc 5117

<210> 6272
<211> 1132
<212> PRT
<213> Homo sapien

<400> 6272
 Met Gly Met Ala Cys Leu Thr Met Thr Glu Met Glu Gly Thr Ser
   1               5                  10                  15

 Thr Ser Ser Ile Tyr Gln Asn Gly Asp Ile Ser Gly Asn Ala Asn
                  20                  25                  30

 Ser Met Lys Gln Ile Asp Pro Val Leu Gln Val Tyr Leu Tyr His
                  35                  40                  45

 Ser Leu Gly Lys Ser Glu Ala Asp Tyr Leu Thr Phe Pro Ser Gly
                  50                  55                  60

 Glu Tyr Val Ala Glu Glu Ile Cys Ile Ala Ala Ser Lys Ala Cys
                  65                  70                  75

 Gly Ile Thr Pro Val Tyr His Asn Met Phe Ala Leu Met Ser Glu
                  80                  85                  90

 Thr Glu Arg Ile Trp Tyr Pro Pro Asn His Val Phe His Ile Asp
                  95                 100                 105

 Glu Ser Thr Arg His Asn Val Leu Tyr Arg Ile Arg Phe Tyr Phe
                 110                 115                 120

 Pro Arg Trp Tyr Cys Ser Gly Ser Asn Arg Ala Tyr Arg His Gly
                 125                 130                 135

 Ile Ser Arg Gly Ala Glu Ala Pro Leu Leu Asp Asp Phe Val Met
                 140                 145                 150

 Ser Tyr Leu Phe Ala Gln Trp Arg His Asp Phe Val His Gly Trp
                 155                 160                 165

 Ile Lys Val Pro Val Thr His Glu Thr Gln Glu Glu Cys Leu Gly
                 170                 175                 180

 Met Ala Val Leu Asp Met Met Arg Ile Ala Lys Glu Asn Asp Gln
                 185                 190                 195

 Thr Pro Leu Ala Ile Tyr Asn Ser Ile Ser Tyr Lys Thr Phe Leu
                 200                 205                 210

 Pro Lys Cys Ile Arg Ala Lys Ile Gln Asp Tyr His Ile Leu Thr
                 215                 220                 225

 Arg Lys Arg Ile Arg Tyr Arg Phe Arg Arg Phe Ile Gln Gln Phe
                 230                 235                 240

 Ser Gln Cys Lys Ala Thr Ala Arg Asn Leu Lys Leu Lys Tyr Leu
                 245                 250                 255

 Ile Asn Leu Glu Thr Leu Gln Ser Ala Phe Tyr Thr Glu Lys Phe
                 260                 265                 270

 Glu Val Lys Glu Pro Gly Ser Gly Pro Ser Gly Glu Glu Ile Phe
                 275                 280                 285

 Ala Thr Ile Ile Ile Thr Gly Asn Gly Gly Ile Gln Trp Ser Arg
                 290                 295                 300

 Gly Lys His Lys Glu Ser Glu Thr Leu Thr Glu Gln Asp Leu Gln
                 305                 310                 315

 Leu Tyr Cys Asp Phe Ser Asn Ile Ile Asp Val Ser Ile Lys Gln
                 320                 325                 330

 Ala Asn Gln Glu Gly Ser Asn Glu Ser Arg Val Val Thr Ile His
                 335                 340                 345

 Lys Gln Asp Gly Lys Asn Leu Glu Ile Glu Leu Ser Ser Leu Arg
                 350                 355                 360

 Glu Ala Leu Ser Phe Val Ser Leu Ile Asp Gly Tyr Tyr Arg Leu
                 365                 370                 375

 Thr Ala Asp Ala His His Tyr Leu Cys Lys Glu Val Ala Pro Pro
                 380                 385                 390

 Ala Val Leu Glu Asn Ile Gln Ser Asn Cys His Gly Pro Ile Ser
                 395                 400                 405

 Met Asp Phe Ala Ile Ser Lys Leu Lys Lys Ala Gly Asn Gln Thr
                 410                 415                 420

 Gly Leu Tyr Val Leu Arg Cys Ser Pro Lys Asp Phe Asn Lys Tyr
                 425                 430                 435

 Phe Leu Thr Phe Ala Val Glu Arg Glu Asn Val Ile Glu Tyr Lys
                 440                 445                 450

 His Cys Leu Ile Thr Lys Asn Glu Asn Glu Glu Tyr Asn Leu Ser
                 455                 460                 465

 Gly Thr Lys Lys Asn Phe Ser Ser Leu Lys Asp Leu Leu Asn Cys
                 470                 475                 480

 Tyr Gln Met Glu Thr Val Arg Ser Asp Asn Ile Ile Phe Gln Phe
                 485                 490                 495

 Thr Lys Cys Cys Pro Pro Lys Pro Lys Asp Lys Ser Asn Leu Leu
                 500                 505                 510

 Val Phe Arg Thr Asn Gly Val Ser Asp Val Pro Thr Ser Pro Thr
                 515                 520                 525

 Leu Gln Arg Pro Thr His Met Asn Gln Met Val Phe His Lys Ile
                 530                 535                 540

 Arg Asn Glu Asp Leu Ile Phe Asn Glu Ser Leu Gly Gln Gly Thr
                 545                 550                 555

 Phe Thr Lys Ile Phe Lys Gly Val Arg Arg Glu Val Gly Asp Tyr
                 560                 565                 570

 Gly Gln Leu His Glu Thr Glu Val Leu Leu Lys Val Leu Asp Lys
                 575                 580                 585

 Ala His Arg Asn Tyr Ser Glu Ser Phe Phe Glu Ala Ala Ser Met
                 590                 595                 600

 Met Ser Lys Leu Ser His Lys His Leu Val Leu Asn Tyr Gly Val
                 605                 610                 615

 Cys Val Cys Gly Asp Glu Asn Ile Leu Val Gln Glu Phe Val Lys
                 620                 625                 630

 Phe Gly Ser Leu Asp Thr Tyr Leu Lys Lys Asn Lys Asn Cys Ile
                 635                 640                 645

 Asn Ile Leu Trp Lys Leu Glu Val Ala Lys Gln Leu Ala Trp Ala
                 650                 655                 660

 Met His Phe Leu Glu Glu Asn Thr Leu Ile His Gly Asn Val Cys
                 665                 670                 675

 Ala Lys Asn Ile Leu Leu Ile Arg Glu Glu Asp Arg Lys Thr Gly
                 680                 685                 690

 Asn Pro Pro Phe Ile Lys Leu Ser Asp Pro Gly Ile Ser Ile Thr
                 695                 700                 705

 Val Leu Pro Lys Asp Ile Leu Gln Glu Arg Ile Pro Trp Val Pro
                 710                 715                 720

 Pro Glu Cys Ile Glu Asn Pro Lys Asn Leu Asn Leu Ala Thr Asp
                 725                 730                 735

 Lys Trp Ser Phe Gly Thr Thr Leu Trp Glu Ile Cys Ser Gly Gly
                 740                 745                 750

 Asp Lys Pro Leu Ser Ala Leu Asp Ser Gln Arg Lys Leu Gln Phe
                 755                 760                 765

 Tyr Glu Asp Arg His Gln Leu Pro Ala Pro Lys Trp Ala Glu Leu
                 770                 775                 780

 Ala Asn Leu Ile Asn Asn Cys Met Asp Tyr Glu Pro Asp Phe Arg
                 785                 790                 795

 Pro Ser Phe Arg Ala Ile Ile Arg Asp Leu Asn Ser Leu Phe Thr
                 800                 805                 810

 Pro Asp Tyr Glu Leu Leu Thr Glu Asn Asp Met Leu Pro Asn Met
                 815                 820                 825

 Arg Ile Gly Ala Leu Gly Phe Ser Gly Ala Phe Glu Asp Arg Asp
                 830                 835                 840

 Pro Thr Gln Phe Glu Glu Arg His Leu Lys Phe Leu Gln Gln Leu
                 845                 850                 855

 Gly Lys Gly Asn Phe Gly Ser Val Glu Met Cys Arg Tyr Asp Pro
                 860                 865                 870

 Leu Gln Asp Asn Thr Gly Glu Val Val Ala Val Lys Lys Leu Gln
                 875                 880                 885

 His Ser Thr Glu Glu His Leu Arg Asp Phe Glu Arg Glu Ile Glu
                 890                 895                 900

 Ile Leu Lys Ser Leu Gln His Asp Asn Ile Val Lys Tyr Lys Gly
                 905                 910                 915

 Val Cys Tyr Ser Ala Gly Arg Arg Asn Leu Lys Leu Ile Met Glu
                 920                 925                 930

 Tyr Leu Pro Tyr Gly Ser Leu Arg Asp Tyr Leu Gln Lys His Lys
                 935                 940                 945

 Glu Arg Ile Asp His Ile Lys Leu Leu Gln Tyr Thr Ser Gln Ile
                 950                 955                 960

 Cys Lys Gly Met Glu Tyr Leu Gly Thr Lys Arg Tyr Ile His Arg
                 965                 970                 975

 Asp Leu Ala Thr Arg Asn Ile Leu Val Glu Asn Glu Asn Arg Val
                 980                 985                 990

 Lys Ile Gly Asp Phe Gly Leu Thr Lys Val Leu Pro Gln Asp Lys
                 995                1000                1005

 Glu Tyr Tyr Lys Val Lys Glu Pro Gly Glu Ser Pro Ile Phe Trp
                1010                1015                1020

 Tyr Ala Pro Glu Ser Leu Thr Glu Ser Lys Phe Ser Val Ala Ser
                1025                1030                1035

 Asp Val Trp Ser Phe Gly Val Val Leu Tyr Glu Leu Phe Thr Tyr
                1040                1045                1050

 Ile Glu Lys Ser Lys Ser Pro Pro Ala Glu Phe Met Arg Met Ile
                1055                1060                1065

 Gly Asn Asp Lys Gln Gly Gln Met Ile Val Phe His Leu Ile Glu
                1070                1075                1080

 Leu Leu Lys Asn Asn Gly Arg Leu Pro Arg Pro Asp Gly Cys Pro
                1085                1090                1095

 Asp Glu Ile Tyr Met Ile Met Thr Glu Cys Trp Asn Asn Asn Val
                1100                1105                1110

 Asn Gln Arg Pro Ser Phe Arg Asp Leu Ala Leu Arg Val Asp Gln
                1115                1120                1125

 Ile Arg Asp Asn Met Ala Gly
                1130

<210> 6273
<211> 604
<212> DNA
<213> Homo sapien

<400> 6273
 gcagacgcag gggtcggcgc cgggtgagag cgtgcggccg gattcaccac 50

 aacatggcaa atctttttat aaggaaaatg gtgaaccctc tgctctatct 100

 cagtcgtcac acggtgaagc ctcgagccct ctccacattt ctatttggat 150

 ccattcgagg tgcagccccc gtggctgtgg aacccggggc agcagtgcgc 200

 tcacttctct cacccggcct cctgccccat ctgctgcctg cgctggggtt 250

 caaaaacaag actgtcctta agaagcgctg caaggactgt tacctggtga 300

 agaggcgggg tcggtggtac gtctactgta aaacccatcc gaggcacaag 350

 cagagacaga tgtagaccct ttccctccag agtcacgcac atactcgtca 400

 tcgcatcact tgggagaatg gttgtatctt atggaaggaa ttatcacatc 450

 aaggagtcag gggaaagtga ctggaagcaa acgccctaaa agttacccat 500

 cacgtttcag tgtaaatgag taactataga agacattgcg ttatcttatt 550

 tccaaaacgt tccaactaaa aaacattttc ctattaaaat agaccttccg 600

 aata 604

<210> 6274
<211> 103
<212> PRT
<213> Homo sapien

<400> 6274
 Met Ala Asn Leu Phe Ile Arg Lys Met Val Asn Pro Leu Leu Tyr
   1               5                  10                  15

 Leu Ser Arg His Thr Val Lys Pro Arg Ala Leu Ser Thr Phe Leu
                  20                  25                  30

 Phe Gly Ser Ile Arg Gly Ala Ala Pro Val Ala Val Glu Pro Gly
                  35                  40                  45

 Ala Ala Val Arg Ser Leu Leu Ser Pro Gly Leu Leu Pro His Leu
                  50                  55                  60

 Leu Pro Ala Leu Gly Phe Lys Asn Lys Thr Val Leu Lys Lys Arg
                  65                  70                  75

 Cys Lys Asp Cys Tyr Leu Val Lys Arg Arg Gly Arg Trp Tyr Val
                  80                  85                  90

 Tyr Cys Lys Thr His Pro Arg His Lys Gln Arg Gln Met
                  95                 100

<210> 6275
<211> 1325
<212> DNA
<213> Homo sapien

<400> 6275
 gaggtattca agaatgccca gccccctata cgggatgcca cagatctgag 50

 agaaaacatg cagaatgcgg tggtgtcatt caaggagctg tgtggcctct 100

 cctctgtggc caatctcatg cagtgcatgt tggcggtgtc tccccgcttt 150

 ctggggcccg ataacacacc cctagtggtc ctaaatctca gcgagcagta 200

 ccccacaatg gagctgcagg gaattgtgcc ggaggttctg aagaagatcg 250

 taacaactta tgacatgatg attcagtccc tcaaggcgtt gattgaaaat 300

 gcagatgctg tatatgaaaa gatcgtacat tgtcagaagg cagccatgga 350

 attccatgaa cacttgcaca gcataggcac caaggaaggt ttgaaggaaa 400

 gaaaactaca aaaagcagtg gagagcttta cctggaatat taccatctta 450

 aagggacaag cagatctttt gaaatatgct aagaatgaga cattggagaa 500

 cctgaaacaa atccattttg ctgctgtttc atgtggactg aataaaccag 550

 gcaccgaaaa tgctgatgtc cagaagccac gccggagctt ggaagtcata 600

 cccgaaaaag caaacgatga aactggagaa tgaggaaact tacaataaac 650

 cattatggag tttataactc taggaccaat tgtagtcaga tgggacattt 700

 gctttgcact cactaatgag aataatattc gggattttaa agcacaactg 750

 gaatagctaa ttacagtcta ttaaaactgt gaatgtatgt agcaatcctg 800

 cgtgtgaagg caaataaact ctttaacagg caattatatt gctggccaaa 850

 atatgctata tttgtataca aagacattct aactcagttc cagtatgaag 900

 aaagattatt cactctagct ccactgagaa acattttcct aagtgaaaac 950

 aatttcttaa gatggaaatg gattggattg tcaaattatt atttattgga 1000

 gaaaaaaacc tgatctacac atttttactt atatggggtt gccagagtct 1050

 ctgggttcta gatgattttg gtggcatgct tgctgagcca taattactaa 1100

 agagaatgta agtggacggg ttccctgaat ccccggggtc cttggagagc 1150

 catcgaggag aatgtgcaat tggactgaag ctccctggct gaagatacat 1200

 gccgagtcag cacatgggta gagatgatgt aaaagcagcc aatctggaaa 1250

 caatacattg taaatagttt ttcattgtat gaagtagtgt tcacattaaa 1300

 aagatgtttt atgataaaaa aaaaa 1325

<210> 6276
<211> 598
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 124
<223> Unknown base

<400> 6276
 cataacacag ccagcttttt gctagccaga ccaaactcaa agagcaatgg 50

 ctgtacttct gaaatagcaa cactttgtcc tagctgagat ttggtaataa 100

 gatttttttt ttaagttttt aaangaagct cagtggttga aagtctgctt 150

 aactgaaaca gtaacatcca tgatgtgtgt tttgtgcatg tttgtatttg 200

 aaaggccttc atgtttttgt ttcttgtttg tttttctctc ctaagacctt 250

 gtcttttttt tgtagcaaaa gttttttttt ttttttcctt ttacttctca 300

 gttgactgaa ttctgttttc accggatttt ttgactaaaa tagctattgc 350

 aacagaggct actcttgggt taaggaagaa tgtagtttcg ttttatgttt 400

 aatatcgctc aaagaaaaat aaaagcatct ccctctaaca ccaccagact 450

 tttcctctct gtaccttatc atgtaaattt tgctatttga ttttcacctg 500

 ggttgtttcc tttaatgtgc aaaaatttaa ggctatttag ctgacaactg 550

 cctagggttg taaaacaggt tatcaagaat ctgaaagtct aagatagg 598

<210> 6277
<211> 2093
<212> DNA
<213> Homo sapien

<400> 6277
 gccccatgca agtccaaaac ccagcaggca aatcttagag ctccaaaatg 50

 acctcctttg actccatgtg tcacatctag gtgatgcaag aagtgggttc 100

 ccagggtctt gggcagcccc gcccctgtgg ctttgcaggg tacggccccc 150

 ccttctggct gcattgagtg tctgcagctt ttccaggcac acagtgcaag 200

 ctgtcagtgg atctaccatt ctggggtctg gaggatggtg gcccctttgt 250

 gacagctctg cttggcagta ccccagtggg gactctgtgt gggggctcca 300

 accccatatt tccctttgac actgccctag cagaggttat ccatgaggcc 350

 cccccgctcc cgtgcacagc aaacttttgc ctggatttcc aggcattttc 400

 atacatcttc tgaaatctag gcggaggttc atgaacgtta attcttcggt 450

 gcatctgcag gcttaacacc acctagaacc tgaaaggctt ggaacttgca 500

 ccctctgaag ccatggcctg aggtgtacct tggccccttt tacctgtggc 550

 aggagcagct gggatgcagg gcaccaggtt cctaggctgc acacagcagg 600

 gggttccgga ctcacaagag catttttcct tctaagcctc ctggcctgtg 650

 atgggagggt ctgctgtgag ggtctctaac atgccctgga gacatttgcc 700

 ccattgtctt ggtgattaac atttggctcc tcattactta tgcaaatttc 750

 tacaacccag tctcctgaga aaatagattt ttcttttctg ttgcatcatc 800

 aggctacaaa ttttctgaac ttttatgctc tgcttcttct cgaatgcttt 850

 gctgcttaga aatttcttct gtcagatacc ttaaatcatc tctctcaagt 900

 tcaaagttcc acagatctct agggaactct agaaaaaaat tcttattttg 950

 actctttccc gcctatctta tgcccgtttc taatacaggt gcacagtgcc 1000

 tgcagtgtct ttgcatagta agagtgactt tactccattt cccaacaaat 1050

 tcctcatctc cctctgagac cacctccgcc tggaccttat tgtccatatc 1100

 actattaaca ttttggtcaa agccattcaa caagtctcta ggaagttcca 1150

 aactttccca cattttccta tcctcttctg agccttccaa actgttccag 1200

 cctctccctg ttacccattt ccaaagttgc ttccacattt tcgggtatct 1250

 ttacagcagc agcccactct actggtatca acttattgta ttagtctgtt 1300

 ctcacactgc aaataaagac atacctgaga ctgggtaatt tataaaggaa 1350

 agaggttgaa ttgactcaca gttctgcatg gctggggagg cctcacaatc 1400

 atggtggaag gcaaggaggt gcaaaagcat gtctcacata gtggcaaggc 1450

 aggagagagc atgtgcaggg gagctcccat ttataaaacc atcagatctc 1500

 atgagactta gtcactacca cgagaacagt atggggggaa ccatccccat 1550

 gattcagtta tctgcacctg gccccaccct tgacacgtgg gaattattcc 1600

 aatgcaaggt gagatttggg tggggaccca tccaaactat gtcagtatgt 1650

 tttgacttct ggcttgattg ctaggttgca tagaggacaa acatggaaat 1700

 taatgaagta ccttaatatc tggcttcaga tcttagacag gatcagaggg 1750

 ccagctcaaa tttgcaagga ggggaggtag atcccaccat tttatgggtg 1800

 aatggcaaaa tcaaacagaa attatgtggg atgggagata ctgatgcagg 1850

 catctttgga aacattctac ttagctaatt ttatgctagg ctttaggtca 1900

 agaaggagag agagagctga catgctgtgg tacacactta ttgtcccagc 1950

 gacttggaaa gctgaggcag gaggattgct tgatcccagg agtttgaggt 2000

 agtgtgcgat gatcgttctt gtgaatagcc actagccact gaactccagc 2050

 ttgggcaaca ttgagacacc ctgtctctta atttaaaaaa aaa 2093

<210> 6278
<211> 1469
<212> DNA
<213> Homo sapien

<400> 6278
 ctttcttttt ctcttggagc tgagctataa gacaacagga ctgaacaggg 50

 agccaactgt ttctttgaac agtaaatcag gaacaccaat ggaccaaaat 100

 gaacacagtc actggggacc acatgcaaag ggccaatgtg ccagcagatc 150

 tgagctgaga atcatcctgg tgggcaaaac aggaactggc aaaagtgctg 200

 cagggaacag catcctcagg aagcaagcat ttgaatcgaa gctgggttcc 250

 cagaccttga ctaagacttg cagcaaaagt cagggaagct ggggaaatag 300

 agagattgtc attattgaca caccagatat gttttcttgg aaggaccact 350

 gtgaagctct gtacaaagag gtgcagaggt gctacttgct gtctgcacca 400

 ggaccccatg tgctgctcct ggtgactcag ctgggccgct atacctcaca 450

 ggaccagcag gctgcacaga gggtgaagga gatctttgga gaggatgcca 500

 tgggacacac aattgtcctc tttacccaca aggaagacct caatggtggc 550

 tccctgatgg attacatgca cgactcagat aacaaagccc taagcaagct 600

 ggtggcagca tgtggtgggc gaatctgtgc ctttaataac cgtgctgaag 650

 ggagcaatca ggatgaccaa gtgaaggaac taatggactg tattgaggat 700

 ctgttgatgg agaaaaatgg tgatcactat accaatgggt tgtacagcct 750

 aatacagagg tctaaatgtg gacctgtggg atcagatgaa agagtaaagg 800

 aattcaaaca gagccttata aagtacatgg aaactcaaag aagttacaca 850

 gccttggctg aagcaaactg cctaaaagga gccttaatca aaacacaact 900

 gtgtgtttta ttttgtattc agttgtttct cagattgata attctgtggc 950

 tttgcatact gcacagcatg tgcaatttgt tttgttgctt actctttagt 1000

 atgtgcaatt tattctgcag tttgctgttt attataccca aaaagttaat 1050

 gatatttttg agaacagtta ttagactaga acgcaagact cctaggttat 1100

 agttacagat cccagttatt atttactcac tatcatttag tgggtgaatc 1150

 acagtaattt ccctgtaaaa tgtggtacct gaagtcatat ttgagattct 1200

 atgaaatgtt taaatctgaa catcactcca attattaatg aaccaaatca 1250

 tacgataagt tactgtttgc attgaaatat aatatcaaag ccttttgaaa 1300

 tctgtaaaca taaaattcct ctcattttca aatatctaaa gccagtttta 1350

 tgttcctaaa atctcatttt cttctttcta gtactactat ttctactgaa 1400

 tataatgaaa atggcaataa aataatatta cataaactga aaaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaa 1469

<210> 6279
<211> 337
<212> PRT
<213> Homo sapien

<400> 6279
 Met Asp Gln Asn Glu His Ser His Trp Gly Pro His Ala Lys Gly
   1               5                  10                  15

 Gln Cys Ala Ser Arg Ser Glu Leu Arg Ile Ile Leu Val Gly Lys
                  20                  25                  30

 Thr Gly Thr Gly Lys Ser Ala Ala Gly Asn Ser Ile Leu Arg Lys
                  35                  40                  45

 Gln Ala Phe Glu Ser Lys Leu Gly Ser Gln Thr Leu Thr Lys Thr
                  50                  55                  60

 Cys Ser Lys Ser Gln Gly Ser Trp Gly Asn Arg Glu Ile Val Ile
                  65                  70                  75

 Ile Asp Thr Pro Asp Met Phe Ser Trp Lys Asp His Cys Glu Ala
                  80                  85                  90

 Leu Tyr Lys Glu Val Gln Arg Cys Tyr Leu Leu Ser Ala Pro Gly
                  95                 100                 105

 Pro His Val Leu Leu Leu Val Thr Gln Leu Gly Arg Tyr Thr Ser
                 110                 115                 120

 Gln Asp Gln Gln Ala Ala Gln Arg Val Lys Glu Ile Phe Gly Glu
                 125                 130                 135

 Asp Ala Met Gly His Thr Ile Val Leu Phe Thr His Lys Glu Asp
                 140                 145                 150

 Leu Asn Gly Gly Ser Leu Met Asp Tyr Met His Asp Ser Asp Asn
                 155                 160                 165

 Lys Ala Leu Ser Lys Leu Val Ala Ala Cys Gly Gly Arg Ile Cys
                 170                 175                 180

 Ala Phe Asn Asn Arg Ala Glu Gly Ser Asn Gln Asp Asp Gln Val
                 185                 190                 195

 Lys Glu Leu Met Asp Cys Ile Glu Asp Leu Leu Met Glu Lys Asn
                 200                 205                 210

 Gly Asp His Tyr Thr Asn Gly Leu Tyr Ser Leu Ile Gln Arg Ser
                 215                 220                 225

 Lys Cys Gly Pro Val Gly Ser Asp Glu Arg Val Lys Glu Phe Lys
                 230                 235                 240

 Gln Ser Leu Ile Lys Tyr Met Glu Thr Gln Arg Ser Tyr Thr Ala
                 245                 250                 255

 Leu Ala Glu Ala Asn Cys Leu Lys Gly Ala Leu Ile Lys Thr Gln
                 260                 265                 270

 Leu Cys Val Leu Phe Cys Ile Gln Leu Phe Leu Arg Leu Ile Ile
                 275                 280                 285

 Leu Trp Leu Cys Ile Leu His Ser Met Cys Asn Leu Phe Cys Cys
                 290                 295                 300

 Leu Leu Phe Ser Met Cys Asn Leu Phe Cys Ser Leu Leu Phe Ile
                 305                 310                 315

 Ile Pro Lys Lys Leu Met Ile Phe Leu Arg Thr Val Ile Arg Leu
                 320                 325                 330

 Glu Arg Lys Thr Pro Arg Leu
                 335

<210> 6280
<211> 2764
<212> DNA
<213> Homo sapien

<400> 6280
 agacgcgcaa gggcgccgat ggaggcagac tcgccagcgg gccccggcgc 50

 cccagagccc ctcgcggagg gagcggcggc cgagttctcc agcctgctgc 100

 gcaggataaa aggcaaactc ttcacctgga atattttgaa aacaattgcc 150

 ctgggtcaga cgttgtcctt gtgtatatgt gggacagcca tcaccagcca 200

 gtatttggca gaaagataca aagtgaacac ccccatgctt cagagcttta 250

 tcaattattg cttgctgttc ctaatttata cagtgatgct ggcatttcga 300

 tcaggcagtg ataacctttt agtaatcttg aaaagaaaat ggtggaagta 350

 catcctgctg ggactagcag atgtggaagc taattatgtg atcgtcagag 400

 cctaccagta cacaactcta accagtgtcc agcttttgga ttgctttggg 450

 attcctgtgt tgatggctct gtcatggttt attcttcatg caagatacag 500

 agtgatccac ttcatcgccg tggctgtctg tctgttgggt gtaggaacca 550

 tggttggtgc agacatacta gcagggaggg aagacaattc agggagtgat 600

 gtattgattg gtgacatctt ggtccttctt ggggcttccc tctatgccat 650

 ttcaaatgtt tgtgaggaat acatcgtgaa gaagctgagc agacaggagt 700

 ttttaggaat ggtgggcctg tttggaacaa ttatcagtgg tatacagcta 750

 ttgattgtgg aatataagga tattgccagc attcattggg actggaaaat 800

 tgccctgctg ttcgtggcat ttgccctgtg tatgttttgc ctgtacagct 850

 tcatgccatt ggtgattaaa gtcactagtg ccacttccgt caacctgggc 900

 atcctgacag cggacctcta cagccttttt gttggactct ttctgtttgg 950

 ctataagttt tcaggactct acatcctgtc cttcactgtc atcatggtgg 1000

 ggtttatcct gtactgctcc acccctactc gcacggccga gccggctgaa 1050

 agcagcgtgc ctccagtcac cagcattggg attgacaacc tggggctgaa 1100

 gctggaggag aacctccagg agacccactc tgctgtcttg tagctggaga 1150

 agatggcgca cccatccccc accaggataa agcagagcct gctgcctgct 1200

 gaggggacac ttggggaaat agcagactca gaatggacac tctacaaccc 1250

 tgggttggat ccagtggtta ggttttagaa aggaacactg aacaaagttc 1300

 aaaagtagaa ataccaaaat agagcagaaa ccaagctaag agtgtgtttc 1350

 tgtgtttgag gaccaatatc tgttcgtgtt gaggagatga ggtgcagact 1400

 ccacactggg gtcttagagg caccggtggg aaagcaggac tggggagaga 1450

 tccaggactg agccagcctc aggccagggc gggaaagcag gctgtccagg 1500

 ctgggcttgg tggtcaggaa caggggcagc tcacggtggc tctggagtac 1550

 gtttcctctg tcagatgctt caaggttttt tttttttttt ttttttgctg 1600

 aggcagttat tgtccacagg cctttgggta cagatgaggc ctcggggctg 1650

 actgcatgtg gcagaaaacg ggtgggtcag cccttgaaaa gtcttgagat 1700

 ataagtgtga gtactataca agcattaaac tggagtgcag taaacctagg 1750

 aaccttccca caattgtttt tttgtttgtt tgagatgcag agtctagagt 1800

 gcagtggtgc aagctcagct tactgtaacc tctgcctcct ggattcaagt 1850

 gttagtagct gggattacaa aagcatgtgg ccccacgccc agctaagttt 1900

 tgtattttta gtagacatgg ggtttcacca tgttgcccag gctggtcttg 1950

 acctcccgac ctcaagtgat ctgcctgccc cgacctccca aagtgctggg 2000

 attacaggct tgagccaccg tgccaggcct gttttgtttg tttttgtaga 2050

 gagatggggt ttcgccatgt tgcccaggct aatctcaaat tcctgagcta 2100

 aagcgatctg cccacctcgg cctccgaaag tgctaggatt acagatgtga 2150

 accactgtgc ctggcctgtt tgtttgtttg tttaaaacat ttctccatca 2200

 ctcattccag gtcccagagc aaactctctc tgctctcgga gcctgtgaca 2250

 ctggctatgt gctccacagt ttcagtccca ggtcatactc tccaacagtt 2300

 ttcagagctc catatatatg tagatgccat cctttctaaa aacttctcac 2350

 gacctcctgg aatattccta ttgatctcat tttatttagc atcagctcaa 2400

 gaaactaagt cttagtgcac agtatcacaa caaagaaaaa gctttgtttt 2450

 tataactggt aaaaacaaga aaagattctc atcaaaatga aaatataaaa 2500

 ttaatcattt ctcaccaaag agtatgcctg ggagcctcca gctgttaaaa 2550

 gacaatgcta ttactacttc ttatcaaaaa tctgtaatgc cctgtgattt 2600

 ttatgatact tcttcaatac aaagtgttaa tatgtgtcat cagtataata 2650

 acaaccaaca aaatgccact ttcagaaaac tgtatgtaaa ttttttgtaa 2700

 caatgtaaaa aagaaatggg gagtaagtgt tcacatcatt aaaaggcttt 2750

 gaattcatgg aaat 2764

<210> 6281
<211> 374
<212> PRT
<213> Homo sapien

<400> 6281
 Met Glu Ala Asp Ser Pro Ala Gly Pro Gly Ala Pro Glu Pro Leu
   1               5                  10                  15

 Ala Glu Gly Ala Ala Ala Glu Phe Ser Ser Leu Leu Arg Arg Ile
                  20                  25                  30

 Lys Gly Lys Leu Phe Thr Trp Asn Ile Leu Lys Thr Ile Ala Leu
                  35                  40                  45

 Gly Gln Thr Leu Ser Leu Cys Ile Cys Gly Thr Ala Ile Thr Ser
                  50                  55                  60

 Gln Tyr Leu Ala Glu Arg Tyr Lys Val Asn Thr Pro Met Leu Gln
                  65                  70                  75

 Ser Phe Ile Asn Tyr Cys Leu Leu Phe Leu Ile Tyr Thr Val Met
                  80                  85                  90

 Leu Ala Phe Arg Ser Gly Ser Asp Asn Leu Leu Val Ile Leu Lys
                  95                 100                 105

 Arg Lys Trp Trp Lys Tyr Ile Leu Leu Gly Leu Ala Asp Val Glu
                 110                 115                 120

 Ala Asn Tyr Val Ile Val Arg Ala Tyr Gln Tyr Thr Thr Leu Thr
                 125                 130                 135

 Ser Val Gln Leu Leu Asp Cys Phe Gly Ile Pro Val Leu Met Ala
                 140                 145                 150

 Leu Ser Trp Phe Ile Leu His Ala Arg Tyr Arg Val Ile His Phe
                 155                 160                 165

 Ile Ala Val Ala Val Cys Leu Leu Gly Val Gly Thr Met Val Gly
                 170                 175                 180

 Ala Asp Ile Leu Ala Gly Arg Glu Asp Asn Ser Gly Ser Asp Val
                 185                 190                 195

 Leu Ile Gly Asp Ile Leu Val Leu Leu Gly Ala Ser Leu Tyr Ala
                 200                 205                 210

 Ile Ser Asn Val Cys Glu Glu Tyr Ile Val Lys Lys Leu Ser Arg
                 215                 220                 225

 Gln Glu Phe Leu Gly Met Val Gly Leu Phe Gly Thr Ile Ile Ser
                 230                 235                 240

 Gly Ile Gln Leu Leu Ile Val Glu Tyr Lys Asp Ile Ala Ser Ile
                 245                 250                 255

 His Trp Asp Trp Lys Ile Ala Leu Leu Phe Val Ala Phe Ala Leu
                 260                 265                 270

 Cys Met Phe Cys Leu Tyr Ser Phe Met Pro Leu Val Ile Lys Val
                 275                 280                 285

 Thr Ser Ala Thr Ser Val Asn Leu Gly Ile Leu Thr Ala Asp Leu
                 290                 295                 300

 Tyr Ser Leu Phe Val Gly Leu Phe Leu Phe Gly Tyr Lys Phe Ser
                 305                 310                 315

 Gly Leu Tyr Ile Leu Ser Phe Thr Val Ile Met Val Gly Phe Ile
                 320                 325                 330

 Leu Tyr Cys Ser Thr Pro Thr Arg Thr Ala Glu Pro Ala Glu Ser
                 335                 340                 345

 Ser Val Pro Pro Val Thr Ser Ile Gly Ile Asp Asn Leu Gly Leu
                 350                 355                 360

 Lys Leu Glu Glu Asn Leu Gln Glu Thr His Ser Ala Val Leu
                 365                 370

<210> 6282
<211> 886
<212> DNA
<213> Homo sapien

<400> 6282
 ggcacgaggc cctcgccgcg gagccgcgcg gagcggagcc ggcgagctaa 50

 cccgagccag ccggcgggcg tcccggaggc ggtggcgcag ggaggggccc 100

 gacgctcgca cgtggccccg gcggccgcca tggcggacag cggcaccgcg 150

 gggggcgcgg cgttggcggc cccggccccc gggccgggca gtggcggccc 200

 aggaccacgc gtctactttc agagcccccc cggggccgca ggagagggcc 250

 cgggcggggc ggacgatgag ggcccagtga ggcgccaagg gaaggtcacc 300

 gtcaagtatg accgcaagga gctacggaag cgcctcaacc tagaggagtg 350

 gatcctggag cagctcacgc gcctctacga ctgccaggaa gaggagatcc 400

 cagaactgga gattgacgtg gatgagctcc tggacatgga gagtgacgat 450

 gcccgggctg ccagggtcaa ggagctgctg gttgactgtt acaaacccac 500

 agaggccttc atttctggcc tgctggacaa gatccggggc atgcagaagc 550

 tgagcacacc ccagaagaag tgagggtccc cgacccagga gaacggtggc 600

 tcccacagga caatcgctgc cccccaacct cgtagcaaca gcaataccgg 650

 gggaccctgc ggccaggcct ggtgccatga gcagggctcc tcgtgcccct 700

 ggcccagggg tctcttcccc tgccccctca gttttccact tttggggttt 750

 tttattgtta ttaaactgat gggacttttt gtgtttttat attgactctg 800

 cggcgcgggc cctttaataa agctaggata cgcctttggt gcaaaaaaaa 850

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 886

<210> 6283
<211> 147
<212> PRT
<213> Homo sapien

<400> 6283
 Met Ala Asp Ser Gly Thr Ala Gly Gly Ala Ala Leu Ala Ala Pro
   1               5                  10                  15

 Ala Pro Gly Pro Gly Ser Gly Gly Pro Gly Pro Arg Val Tyr Phe
                  20                  25                  30

 Gln Ser Pro Pro Gly Ala Ala Gly Glu Gly Pro Gly Gly Ala Asp
                  35                  40                  45

 Asp Glu Gly Pro Val Arg Arg Gln Gly Lys Val Thr Val Lys Tyr
                  50                  55                  60

 Asp Arg Lys Glu Leu Arg Lys Arg Leu Asn Leu Glu Glu Trp Ile
                  65                  70                  75

 Leu Glu Gln Leu Thr Arg Leu Tyr Asp Cys Gln Glu Glu Glu Ile
                  80                  85                  90

 Pro Glu Leu Glu Ile Asp Val Asp Glu Leu Leu Asp Met Glu Ser
                  95                 100                 105

 Asp Asp Ala Arg Ala Ala Arg Val Lys Glu Leu Leu Val Asp Cys
                 110                 115                 120

 Tyr Lys Pro Thr Glu Ala Phe Ile Ser Gly Leu Leu Asp Lys Ile
                 125                 130                 135

 Arg Gly Met Gln Lys Leu Ser Thr Pro Gln Lys Lys
                 140                 145

<210> 6284
<211> 1190
<212> DNA
<213> Homo sapien

<400> 6284
 ggcacgaggc tgaggtgtat ttcgggtctt gctggggctg agagagacca 50

 cagccctttg gggggtacaa acaagagttc agttgctgtg aattctgcca 100

 ctgtgcccag ctctgaagcc tcagctcttg ccaaacagac ccgagaccca 150

 tgtcagcccc actggatgcc gccctccacg cccttcagga ggagcaggcc 200

 agactcaaga tgaggctgtg ggacctgcag cagctgagaa aggagctcgg 250

 ggactccccc aaagacaagg tcccattttc agtgcccaag atccccctgg 300

 tattccgagg acacacccag caggacccgg aagtgcctaa gtctttagtt 350

 tccaatttgc ggatccactg ccctctgctt gcgggctctg ctctgatcac 400

 ctttgatgac cccaaagtgg ctgagcaggt gctgcaacaa aaggagcaca 450

 cgatcaacat ggaggagtgc cggctgcggg tgcaggtcca gcccttggag 500

 ctgcccatgg tcaccaccat ccaggtgatg gtgtccagcc agttgagtgg 550

 ccggagggtg ttggtcactg gatttcctgc cagcctcagg ctgagtgagg 600

 aggagctgct ggacaagcta gagatcttct ttggcaagac taggaacgga 650

 ggtggcgatg tggacgttcg ggagctactg ccagggagtg tcatgctggg 700

 gtttgctagg gatggagtgg ctcagcgtct gtgccaaatc ggccagttca 750

 cagtgccact gggtgggcag caagtccctc tgagagtctc tccgtatgtg 800

 aatggggaga tccagaaggc tgagatcagg tcgcagccag ttccccgctc 850

 ggtactggtg ctcaacattc ctgatatctt ggatggcccg gagctgcatg 900

 acgtcctgga gatccacttc cagaagccca cccgcggggg cggggaggta 950

 gaggccctga cagtcgtacc ccaaggacag cagggcctag cagtcttcac 1000

 ctctgagtca ggctaggggc ctccccttct catcctcccc acccccccgc 1050

 caaggttctc acactggcct gggcttgggt gcccatatag gaggtctgta 1100

 tgttcaccaa cagtgcggag gggtcacaca ttgcaaaaca ctgcccagaa 1150

 cagtaaaaag agcctgcatg ccaaaaaaaa aaaaaaaaaa 1190

<210> 6285
<211> 288
<212> PRT
<213> Homo sapien

<400> 6285
 Met Ser Ala Pro Leu Asp Ala Ala Leu His Ala Leu Gln Glu Glu
   1               5                  10                  15

 Gln Ala Arg Leu Lys Met Arg Leu Trp Asp Leu Gln Gln Leu Arg
                  20                  25                  30

 Lys Glu Leu Gly Asp Ser Pro Lys Asp Lys Val Pro Phe Ser Val
                  35                  40                  45

 Pro Lys Ile Pro Leu Val Phe Arg Gly His Thr Gln Gln Asp Pro
                  50                  55                  60

 Glu Val Pro Lys Ser Leu Val Ser Asn Leu Arg Ile His Cys Pro
                  65                  70                  75

 Leu Leu Ala Gly Ser Ala Leu Ile Thr Phe Asp Asp Pro Lys Val
                  80                  85                  90

 Ala Glu Gln Val Leu Gln Gln Lys Glu His Thr Ile Asn Met Glu
                  95                 100                 105

 Glu Cys Arg Leu Arg Val Gln Val Gln Pro Leu Glu Leu Pro Met
                 110                 115                 120

 Val Thr Thr Ile Gln Val Met Val Ser Ser Gln Leu Ser Gly Arg
                 125                 130                 135

 Arg Val Leu Val Thr Gly Phe Pro Ala Ser Leu Arg Leu Ser Glu
                 140                 145                 150

 Glu Glu Leu Leu Asp Lys Leu Glu Ile Phe Phe Gly Lys Thr Arg
                 155                 160                 165

 Asn Gly Gly Gly Asp Val Asp Val Arg Glu Leu Leu Pro Gly Ser
                 170                 175                 180

 Val Met Leu Gly Phe Ala Arg Asp Gly Val Ala Gln Arg Leu Cys
                 185                 190                 195

 Gln Ile Gly Gln Phe Thr Val Pro Leu Gly Gly Gln Gln Val Pro
                 200                 205                 210

 Leu Arg Val Ser Pro Tyr Val Asn Gly Glu Ile Gln Lys Ala Glu
                 215                 220                 225

 Ile Arg Ser Gln Pro Val Pro Arg Ser Val Leu Val Leu Asn Ile
                 230                 235                 240

 Pro Asp Ile Leu Asp Gly Pro Glu Leu His Asp Val Leu Glu Ile
                 245                 250                 255

 His Phe Gln Lys Pro Thr Arg Gly Gly Gly Glu Val Glu Ala Leu
                 260                 265                 270

 Thr Val Val Pro Gln Gly Gln Gln Gly Leu Ala Val Phe Thr Ser
                 275                 280                 285

 Glu Ser Gly


<210> 6286
<211> 978
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 3, 20, 26, 40, 82
<223> Unknown base

<400> 6286
 tanagaactg agggtcagan tgaccntgcc tcatagtatn cgatcagatt 50

 cagaagatat ctgtttattt acgaaggatg ancccaattc aactcctgaa 100

 aagacagaac agttttatag aaagctttta aacaagcatg gaattaaaac 150

 cgtttctcag attatctccc tccaaactct aaagaaggaa tataaatcct 200

 atgaagccaa gctccgcctt ctgagcagtt ttgatttctt ccttactgat 250

 gccagaatta ggcggctctt accctcactc attgggagac atttctatca 300

 aagaaagaaa gttccagtat ctgtaaacct tctgtccaag aatttatcaa 350

 gagagatcaa tgactgtata ggtggaacag tcttaaacat ttctaaaagt 400

 ggttcttgca gtgctatacg tattggtcac gttggaatgc aaattgagca 450

 catcattgaa aacattgttg ctgtcaccaa aggactttca gaaaaattgc 500

 cagagaagtg ggagagcgtg aaactcctgt ttgtgaaaac tgagaaatcg 550

 gctgcacttc ccatcttttc ctcgtttgtc agcaattggg atgaagccac 600

 caaaagatct ttgcttaata agaagaaaaa agaggcaagg agaaaacgaa 650

 gagaaagaaa ttttgaaaaa caaaaggaga ggaagaagaa gaggcagcag 700

 gctaggaaga ctgcatcagt tcttagtaaa gatgatgtgg cacctgaaag 750

 tggtgatact acagtgaaga aacctgaatc aaagaaggaa cagaccccag 800

 agcatgggaa gaaaaaacgt ggcagaggaa aagcccaagt taaagcaaca 850

 aatgaatccg aagacgaaat cccacagctg gtaccaatag gaaagaagac 900

 tccagctaat gaaaaagtag agattcaaaa acatgccaca ggaaagaagt 950

 ctccaggcaa agagtcctaa tcccagca 978

<210> 6287
<211> 3166
<212> DNA
<213> Homo sapien

<400> 6287
 gcgggaggtt cggagcggga gctcgggctc gcggacggta tggaggacta 50

 cgagcaggag ctgtgcggcg tcgaggatga tttccacaac cagttcgcgg 100

 ccgagctgga ggtgctggca gagctggaag gggcgtcgac tccgtcgccc 150

 tccggggtcc ccctgttcac cgcgggccga cccccgcgga cgttcgagga 200

 ggcccttgcc agaggggacg cggcctccag tcccgcccca gccgcatctg 250

 tgggcagcag ccagggcggc gccaggaaga ggcaggtgga cgccgacctg 300

 cagccggccg ggtccctgcc ccacggtagg ttggcggcat tgccccaggg 350

 cctccggagt gggcgcgagg ctgaggaggc ctctggttcc ctgcatgtgt 400

 ctcccccagc ccccaggatc aaacggccta ggctgcaggt ggtcaagagg 450

 ctgaacttca ggtcggagga gatggaggag ccgccccctc ccgactcctc 500

 gccgacggac atcaccccgc cgccgagccc tgaggacctc gcagagcttt 550

 ggggccacgg agtctcagaa gctgctgccg acgtgggtct cacacgggcc 600

 tcaccagctg cccgcaatcc cgtcctgagg cggcccccca tcttggagga 650

 ctacgtccac gtgacatcca cggagggcgt ccgggcttat ctggtgctgc 700

 gtgctgaccc catggccccg ggggtgcagg gctctctcct ccacgtccca 750

 tggcgaggcg gtggccagct ggacctgctg ggtgtgtcct tagcctccct 800

 gaagaagcag gtcgacggcg agcggcggga gcggctgctt caggaggccc 850

 agaagctttc agacaccctg cacagtctca ggtcggggga ggaggaggca 900

 gcccagccct tgggggcccc tgaggaggag ccgactgacg gtcaagacgc 950

 ctccagtcac tgcctctggg tggatgagtt tgcaccccgc cactacacgg 1000

 agctgctcag tgatgacttc accaaccgct gcctgctcaa gtggctgaag 1050

 ttgtgggacc tggtggtgtt tggccacgag aggccttccc ggaagcccag 1100

 gcccagtgtt gagccggccc gggtcagcaa ggaggccaca gccccaggca 1150

 agtggaagag ccacgaacag gtgctggagg agatgctgga ggctgggctg 1200

 gacccgagcc agcgaccgaa gcagaaggtg gcactgctct gtgggccccc 1250

 ggggctgggg aagaccaccc tggcacacgt gattgcgcgt cacgcggggt 1300

 actctgtggt ggagatgaac gccagtgacg accgtagccc ggaggtcttc 1350

 cgcacacgca tcgaggcggc cacccagatg gagtcggtgc tgggtgctgg 1400

 cgggaagccc aactgcctgg tcatcgatga gatcgacggg gcccccgtgg 1450

 ccgccatcaa cgtcctcctg agcatcctga accgcaaggg gccacaggag 1500

 gtggggccac agggcccggc tgtgccttcg ggaggcggcc gacggcgccg 1550

 ggcagagggg gggctcctca tgaggcccat tatctgcatt tgcaatgacc 1600

 agttcgcacc gtccctgcgg cagctgaagc agcaggcctt cctgctccac 1650

 ttcccgccga ctctgccctc gaggctggtg cagcggctcc aggaggtctc 1700

 cctgcggcag ggcatgaggg ccgacccagg ggtgctggcc gccctctgtg 1750

 agaaaactga caatgacatc cgggcctgca tcaacaccct gcagttcctg 1800

 tacagccggg gccagcggga gctgagcgtg cgggacgtgc aggccacacg 1850

 cgtgggcctc aaggaccagc gcagagggct cttctcggtg tggcaggagg 1900

 tcttccagct gcctcgagcc cagaggcgcc gtgtgggcca ggaccccgcc 1950

 ctgcctgctg acacactcct gctgggtgac ggggacgcgg gctccctcac 2000

 ctccgcctca cagcgattct accgtgtcct gcatgccgct gcctctgcgg 2050

 gcgagcacga gaaggtggtc cagggcttgt ttgacaactt cctgcgtctg 2100

 cggctgcgag actccagcct gggtgctgtg tgtgtggccc tcgactggct 2150

 ggccttcgat gacctgctgg cgggggctgc tcatcacagc cagagcttcc 2200

 agctgctgcg ctacccaccc ttcctgcccg tggccttcca tgtgctgttt 2250

 gcttccagcc acacacccag gatcaccttc cccagcagcc agcaggaggc 2300

 ccagaaccgg atgagccaga tgaggaacct gatccagacg ctggtgtccg 2350

 gcatcgcgcc agccacgcgc agccgggcca cgccccaggc cctgctcctc 2400

 gatgccctct gcctgctcct ggacattctt gcacccaagc tccgccccgt 2450

 gagcacacag ctgtacagca cccgtgaaaa gcaacagctg gccagcctgg 2500

 tgggcacgat gctcgcttac agcctgacct accgccagga gcgcacgccc 2550

 gatggccagt acatctacag gctggagccg aacgtggagg aactctgccg 2600

 cttccctgag ctgcctgccc gcaagcccct cacctaccag acgaagcagc 2650

 tcatcgcccg cgagatcgag gtggagaaga tgcggcgggc ggaggcttct 2700

 gcccgggtag agaacagccc ccaggtggat gggagccccc cagggctcga 2750

 gggtctgctg gggggcattg gggagaaagg ggtgcaccga cctgccccac 2800

 gcaaccatga gcagcggctg gagcacatca tgaggcgagc ggcccgggag 2850

 gaacagcctg agaaggactt ctttggacgt gtggtcgtca ggagcacagc 2900

 agtcccgagt gcaggggaca cggccccgga gcaggactca gtggagcggc 2950

 gcatgggcac agcggtgggc aggagcgagg tctggttccg cttcaacgag 3000

 ggtgtctcca acgccgtgcg gcgcagcctg tacatcaggg acttgctcta 3050

 gttctctgag ccgcggacat gccctcgcat tgcttcccgc agagtgcaga 3100

 gacaggaagc tggagatgtc tttataaagt cacaccttta cagactgtaa 3150

 aaaaaaaaaa aaaaaa 3166

<210> 6288
<211> 1016
<212> PRT
<213> Homo sapien

<400> 6288
 Ala Gly Gly Ser Glu Arg Glu Leu Gly Leu Ala Asp Gly Met Glu
   1               5                  10                  15

 Asp Tyr Glu Gln Glu Leu Cys Gly Val Glu Asp Asp Phe His Asn
                  20                  25                  30

 Gln Phe Ala Ala Glu Leu Glu Val Leu Ala Glu Leu Glu Gly Ala
                  35                  40                  45

 Ser Thr Pro Ser Pro Ser Gly Val Pro Leu Phe Thr Ala Gly Arg
                  50                  55                  60

 Pro Pro Arg Thr Phe Glu Glu Ala Leu Ala Arg Gly Asp Ala Ala
                  65                  70                  75

 Ser Ser Pro Ala Pro Ala Ala Ser Val Gly Ser Ser Gln Gly Gly
                  80                  85                  90

 Ala Arg Lys Arg Gln Val Asp Ala Asp Leu Gln Pro Ala Gly Ser
                  95                 100                 105

 Leu Pro His Gly Arg Leu Ala Ala Leu Pro Gln Gly Leu Arg Ser
                 110                 115                 120

 Gly Arg Glu Ala Glu Glu Ala Ser Gly Ser Leu His Val Ser Pro
                 125                 130                 135

 Pro Ala Pro Arg Ile Lys Arg Pro Arg Leu Gln Val Val Lys Arg
                 140                 145                 150

 Leu Asn Phe Arg Ser Glu Glu Met Glu Glu Pro Pro Pro Pro Asp
                 155                 160                 165

 Ser Ser Pro Thr Asp Ile Thr Pro Pro Pro Ser Pro Glu Asp Leu
                 170                 175                 180

 Ala Glu Leu Trp Gly His Gly Val Ser Glu Ala Ala Ala Asp Val
                 185                 190                 195

 Gly Leu Thr Arg Ala Ser Pro Ala Ala Arg Asn Pro Val Leu Arg
                 200                 205                 210

 Arg Pro Pro Ile Leu Glu Asp Tyr Val His Val Thr Ser Thr Glu
                 215                 220                 225

 Gly Val Arg Ala Tyr Leu Val Leu Arg Ala Asp Pro Met Ala Pro
                 230                 235                 240

 Gly Val Gln Gly Ser Leu Leu His Val Pro Trp Arg Gly Gly Gly
                 245                 250                 255

 Gln Leu Asp Leu Leu Gly Val Ser Leu Ala Ser Leu Lys Lys Gln
                 260                 265                 270

 Val Asp Gly Glu Arg Arg Glu Arg Leu Leu Gln Glu Ala Gln Lys
                 275                 280                 285

 Leu Ser Asp Thr Leu His Ser Leu Arg Ser Gly Glu Glu Glu Ala
                 290                 295                 300

 Ala Gln Pro Leu Gly Ala Pro Glu Glu Glu Pro Thr Asp Gly Gln
                 305                 310                 315

 Asp Ala Ser Ser His Cys Leu Trp Val Asp Glu Phe Ala Pro Arg
                 320                 325                 330

 His Tyr Thr Glu Leu Leu Ser Asp Asp Phe Thr Asn Arg Cys Leu
                 335                 340                 345

 Leu Lys Trp Leu Lys Leu Trp Asp Leu Val Val Phe Gly His Glu
                 350                 355                 360

 Arg Pro Ser Arg Lys Pro Arg Pro Ser Val Glu Pro Ala Arg Val
                 365                 370                 375

 Ser Lys Glu Ala Thr Ala Pro Gly Lys Trp Lys Ser His Glu Gln
                 380                 385                 390

 Val Leu Glu Glu Met Leu Glu Ala Gly Leu Asp Pro Ser Gln Arg
                 395                 400                 405

 Pro Lys Gln Lys Val Ala Leu Leu Cys Gly Pro Pro Gly Leu Gly
                 410                 415                 420

 Lys Thr Thr Leu Ala His Val Ile Ala Arg His Ala Gly Tyr Ser
                 425                 430                 435

 Val Val Glu Met Asn Ala Ser Asp Asp Arg Ser Pro Glu Val Phe
                 440                 445                 450

 Arg Thr Arg Ile Glu Ala Ala Thr Gln Met Glu Ser Val Leu Gly
                 455                 460                 465

 Ala Gly Gly Lys Pro Asn Cys Leu Val Ile Asp Glu Ile Asp Gly
                 470                 475                 480

 Ala Pro Val Ala Ala Ile Asn Val Leu Leu Ser Ile Leu Asn Arg
                 485                 490                 495

 Lys Gly Pro Gln Glu Val Gly Pro Gln Gly Pro Ala Val Pro Ser
                 500                 505                 510

 Gly Gly Gly Arg Arg Arg Arg Ala Glu Gly Gly Leu Leu Met Arg
                 515                 520                 525

 Pro Ile Ile Cys Ile Cys Asn Asp Gln Phe Ala Pro Ser Leu Arg
                 530                 535                 540

 Gln Leu Lys Gln Gln Ala Phe Leu Leu His Phe Pro Pro Thr Leu
                 545                 550                 555

 Pro Ser Arg Leu Val Gln Arg Leu Gln Glu Val Ser Leu Arg Gln
                 560                 565                 570

 Gly Met Arg Ala Asp Pro Gly Val Leu Ala Ala Leu Cys Glu Lys
                 575                 580                 585

 Thr Asp Asn Asp Ile Arg Ala Cys Ile Asn Thr Leu Gln Phe Leu
                 590                 595                 600

 Tyr Ser Arg Gly Gln Arg Glu Leu Ser Val Arg Asp Val Gln Ala
                 605                 610                 615

 Thr Arg Val Gly Leu Lys Asp Gln Arg Arg Gly Leu Phe Ser Val
                 620                 625                 630

 Trp Gln Glu Val Phe Gln Leu Pro Arg Ala Gln Arg Arg Arg Val
                 635                 640                 645

 Gly Gln Asp Pro Ala Leu Pro Ala Asp Thr Leu Leu Leu Gly Asp
                 650                 655                 660

 Gly Asp Ala Gly Ser Leu Thr Ser Ala Ser Gln Arg Phe Tyr Arg
                 665                 670                 675

 Val Leu His Ala Ala Ala Ser Ala Gly Glu His Glu Lys Val Val
                 680                 685                 690

 Gln Gly Leu Phe Asp Asn Phe Leu Arg Leu Arg Leu Arg Asp Ser
                 695                 700                 705

 Ser Leu Gly Ala Val Cys Val Ala Leu Asp Trp Leu Ala Phe Asp
                 710                 715                 720

 Asp Leu Leu Ala Gly Ala Ala His His Ser Gln Ser Phe Gln Leu
                 725                 730                 735

 Leu Arg Tyr Pro Pro Phe Leu Pro Val Ala Phe His Val Leu Phe
                 740                 745                 750

 Ala Ser Ser His Thr Pro Arg Ile Thr Phe Pro Ser Ser Gln Gln
                 755                 760                 765

 Glu Ala Gln Asn Arg Met Ser Gln Met Arg Asn Leu Ile Gln Thr
                 770                 775                 780

 Leu Val Ser Gly Ile Ala Pro Ala Thr Arg Ser Arg Ala Thr Pro
                 785                 790                 795

 Gln Ala Leu Leu Leu Asp Ala Leu Cys Leu Leu Leu Asp Ile Leu
                 800                 805                 810

 Ala Pro Lys Leu Arg Pro Val Ser Thr Gln Leu Tyr Ser Thr Arg
                 815                 820                 825

 Glu Lys Gln Gln Leu Ala Ser Leu Val Gly Thr Met Leu Ala Tyr
                 830                 835                 840

 Ser Leu Thr Tyr Arg Gln Glu Arg Thr Pro Asp Gly Gln Tyr Ile
                 845                 850                 855

 Tyr Arg Leu Glu Pro Asn Val Glu Glu Leu Cys Arg Phe Pro Glu
                 860                 865                 870

 Leu Pro Ala Arg Lys Pro Leu Thr Tyr Gln Thr Lys Gln Leu Ile
                 875                 880                 885

 Ala Arg Glu Ile Glu Val Glu Lys Met Arg Arg Ala Glu Ala Ser
                 890                 895                 900

 Ala Arg Val Glu Asn Ser Pro Gln Val Asp Gly Ser Pro Pro Gly
                 905                 910                 915

 Leu Glu Gly Leu Leu Gly Gly Ile Gly Glu Lys Gly Val His Arg
                 920                 925                 930

 Pro Ala Pro Arg Asn His Glu Gln Arg Leu Glu His Ile Met Arg
                 935                 940                 945

 Arg Ala Ala Arg Glu Glu Gln Pro Glu Lys Asp Phe Phe Gly Arg
                 950                 955                 960

 Val Val Val Arg Ser Thr Ala Val Pro Ser Ala Gly Asp Thr Ala
                 965                 970                 975

 Pro Glu Gln Asp Ser Val Glu Arg Arg Met Gly Thr Ala Val Gly
                 980                 985                 990

 Arg Ser Glu Val Trp Phe Arg Phe Asn Glu Gly Val Ser Asn Ala
                 995                1000                1005

 Val Arg Arg Ser Leu Tyr Ile Arg Asp Leu Leu
                1010                1015

<210> 6289
<211> 4380
<212> DNA
<213> Homo sapien

<400> 6289
 gcatatcttg agtagaactt aacatatctt gaatgggata tttttttctt 50

 ttattcttat gagtggtctc acacaggacc aaacagcagg ccagcatagc 100

 accacgtgat ctgagcttgt ttttactctc tcctttttca taaacagagt 150

 cccagattaa tgccagtagt tgattttggg tctttggggt agtgaagctt 200

 gtggatttga cttctctgat tccttttgct gaccttgagt ggattgtatc 250

 tttcactgtt aattataata atttaaaaat tgagttctac ttactggaca 300

 tgaatctctg cacttgaaag ttaacatatt aaaagcatat tttttttctt 350

 ccttggtttt cttgttcatg tggataaccc agagaatgcc tgaatctaag 400

 gtgccatcct ctgagaatca tcgcccagaa atgtgctcta gctgcaatgt 450

 tcctcttccc attggagata gcagctcctt ctctgggagt tgttccagca 500

 gtccagaaag gatagtttct caaacttcct ctgttgagaa cccattggag 550

 aaccagaaaa atgatcaaaa taattcagat actaagatct ctgagacaga 600

 gacccttaaa tcatcacaga attttcagac tctgccttca tctccacttc 650

 tggtccccca agaatctttg gcctcttctg aggtcaaaga gaatttacgt 700

 atagattctt cttcagcttc acagcatgga cgggatgcca tcctctatct 750

 ccagacacaa gtagctgaaa tgtcccgagt gatacgtgat ctgcagtcca 800

 ggagctgttt tagatttcat cattctaggc caagtgagaa ctcctcagtt 850

 ccttgggaca tctccacctc taaagaggaa aatttatcca cagttgaaga 900

 agaaactgat tacaaatcac catcagctga tgacaaaggg cagccatctg 950

 accccagcca atctagtttc acaggtcttt tgaagagaat ggaacaaaga 1000

 ggtgttataa aaagggtgac attacaatct gaagcggagt catgtgaagg 1050

 gaaacctgat tgtgtgactt ctaaaaaacg tttggttcct ccattgcatc 1100

 ctcttctgag aattgccacc actgaggttt ttaaagaccc tgctgattgc 1150

 catccttctt ccttcatggg acacagggta tatcctgtgg ccaaggacac 1200

 ctctcctttc caaccaaacc caccagctga aggccccatt gtagaagcat 1250

 tagaacacag caaaagagga aacacaacat cccctctaga ttctacctca 1300

 aaagaaatgg aggtcatggg ttgtaggttt taccacgctg cctccattgc 1350

 agcccgagct gctagctaca tggcctatat gactcaatat cagcgtaaac 1400

 tctgggaaga catggaagat ctggttcatg acccagaatt tgatcgtgga 1450

 aaagcaagat gcataatatc tgatggtatg gatgcaggcc tttggcaact 1500

 ttgtactact agggacataa tggactctgt agtcagagtt atggccatgg 1550

 ccatagacta tagacggcag gcctggcttc gacttacatc tctcactaag 1600

 aaaacccagg agaagatctc ccacttgccc tttgatggta cttccctttt 1650

 tggacaagat gtgaaagctg ttgttgcaga agacaacaat ataaaagaaa 1700

 atgactataa agatcacaaa tactataatc agcatcgata cttttatagt 1750

 catgatcaga aagcacatta tcacaataga ggatactcca aaggggattg 1800

 gtacaaacct cgaaaccacc cctatagata tagaaagaag ggagactctc 1850

 cagaacgcca tgggtacaag aattaataac ctgtttaatg ttcagcagag 1900

 tagtcattca agatcctaac tattttactt gttcctcctt gtacaaatag 1950

 gatctacagg taggagatca tctcaaaaac tggatgcatg tctggaatga 2000

 tcacagctga catttgaatt ctagactttt gaaatgaagt atataataaa 2050

 gaaactcatg acttggccaa gtgagcagtg gagactttct tgaaagggtt 2100

 ggacaaatgt ttatccttta tttctggtcc aaaaataagt gtggaggagg 2150

 accactcagg aatctgaatc ctcttgtgat taaagaaaaa tataaagatg 2200

 tgttcctcag gaaaatctta tttgtaaact gaggactagc agattttgaa 2250

 tctagaaata atactagatg tctgtttact aagaccagag gtaaatcctt 2300

 aacttttagg ttatcagtgc ttccttgttc aggcttcagt ttgacagatc 2350

 ttcacaaaat gacacatctg ttaaaatgtc tttatgtcaa gatggtcaac 2400

 tcaccaagag tccgtactac tatcaagctc tgtgagactt cagaatcagc 2450

 catgaagctt tgtgtcaact ggaattcaaa tcaaattttg ccaaatccag 2500

 tttgcttccc cttggaatgg ctagatgtcg caggtctatt atggacacca 2550

 actggaaaaa gacttctacc tgtaacatct ctgtagaaat tgcacagtaa 2600

 ctatcttcat caagactttg atggccacca taccatcact actcataaag 2650

 ctacatgtga gagaattgtt tgttgttatc aatcctaata gtctttgacc 2700

 tatcaagctc tcgtatcaag ctgtaagact gagtcatggt agtctctcac 2750

 tgtaagctgg gcctttcacc aagatggcct tcttaaacaa cctaccttct 2800

 aaacatttaa ttcttttgag cttgatagtg catcacactc taaatacaaa 2850

 aaagatacgc acatcagtgc cctggaaata aaggatgtta cacgatccag 2900

 gcatgcaaat ctgaactcct aagaccaaga attccaaaca tgcctgacaa 2950

 tcttgtcccc ttattgtaat aaagagggat accatcagtc tagattttat 3000

 tgagaatcct taagatttaa agcatagctg tggatgtggt gaagagaaca 3050

 agccacacag ctctgtttct ggatatctaa gtgatgatat ccattaatga 3100

 tttgaaaggc tgaaatcaag atttaagtga tacgctcttg gttaattggt 3150

 tacttaattt agtcagattc ttagtgtaag agacagctta tctttttgct 3200

 cccaattggt cccattaata gtttttcacc atactggaac tggcagcaga 3250

 tacctcaatt atatgtccca cagtatcttc tctttagact caaggtagtg 3300

 gatgtatggt atatcagccc ttagatccat gtcttcacag catgacatca 3350

 ggaatggaga atatgtcaaa tttgaggggt ctgaatacat cacctagtat 3400

 tatttgcttg gcagccaaaa acagttgttt ttattgacag acttaattct 3450

 gtaacttctg cgttttttca tctgcttgat caaggcattt tggatgtact 3500

 gctaatggaa tatggcactg ttttacggtt tatgtggctt ctgttcttgc 3550

 cacagttgtt gcacagtggt aattgatgtt ttctctggtg ccacactttt 3600

 taataatcta ttggaagctc attcctcctc ccccatcata accatattca 3650

 gcacccattt ttaaatctac ttttcttcct tatttgtgct acagaggttg 3700

 atggcgtaaa ttttcctact tggaagaaat tactttatca gttaatttca 3750

 gggtactgta ttgatcttgt ttgtcctatt tgtagattaa acttgaacta 3800

 gtcttaataa aggggatatt gttttgcaaa tttagcccag tcatatcaag 3850

 agttaatatt tatcttattt ttctgtattt tactcaaaat tttatttcca 3900

 cttctgtaga aataggtcca tgccagtgtt ctctacaaag tgtctttcaa 3950

 actaaactct agaagaatat cgattacctg aacagaaaca aaggcctaag 4000

 aaatcataca tttttgtagc ttatgtgtat tgcaccaatc aagcaatccc 4050

 atgtgctctt gatattggca ctgtagtttt atcttagagg acttgccact 4100

 ggagaactca gtggtgagag accttggaaa tgttttatgt ggctgcacat 4150

 aagtgtttct gactagctaa ggctacttca gacttttcac tttccatttg 4200

 tccccttttc cttccctgaa ttagatgcta tgtcataaac ttggtggttt 4250

 ttgaaatact cttatttcaa accttaaact aaaccgaaat aagttatgcc 4300

 tgagaatgcg tttgtctgaa acgattttgg cacttccctt taatatgctt 4350

 ccccttccct ttgcctttta aattgtggtt 4380

<210> 6290
<211> 530
<212> PRT
<213> Homo sapien

<400> 6290
 Val Leu Leu Thr Gly His Glu Ser Leu His Leu Lys Val Asn Ile
   1               5                  10                  15

 Leu Lys Ala Tyr Phe Phe Ser Ser Leu Val Phe Leu Phe Met Trp
                  20                  25                  30

 Ile Thr Gln Arg Met Pro Glu Ser Lys Val Pro Ser Ser Glu Asn
                  35                  40                  45

 His Arg Pro Glu Met Cys Ser Ser Cys Asn Val Pro Leu Pro Ile
                  50                  55                  60

 Gly Asp Ser Ser Ser Phe Ser Gly Ser Cys Ser Ser Ser Pro Glu
                  65                  70                  75

 Arg Ile Val Ser Gln Thr Ser Ser Val Glu Asn Pro Leu Glu Asn
                  80                  85                  90

 Gln Lys Asn Asp Gln Asn Asn Ser Asp Thr Lys Ile Ser Glu Thr
                  95                 100                 105

 Glu Thr Leu Lys Ser Ser Gln Asn Phe Gln Thr Leu Pro Ser Ser
                 110                 115                 120

 Pro Leu Leu Val Pro Gln Glu Ser Leu Ala Ser Ser Glu Val Lys
                 125                 130                 135

 Glu Asn Leu Arg Ile Asp Ser Ser Ser Ala Ser Gln His Gly Arg
                 140                 145                 150

 Asp Ala Ile Leu Tyr Leu Gln Thr Gln Val Ala Glu Met Ser Arg
                 155                 160                 165

 Val Ile Arg Asp Leu Gln Ser Arg Ser Cys Phe Arg Phe His His
                 170                 175                 180

 Ser Arg Pro Ser Glu Asn Ser Ser Val Pro Trp Asp Ile Ser Thr
                 185                 190                 195

 Ser Lys Glu Glu Asn Leu Ser Thr Val Glu Glu Glu Thr Asp Tyr
                 200                 205                 210

 Lys Ser Pro Ser Ala Asp Asp Lys Gly Gln Pro Ser Asp Pro Ser
                 215                 220                 225

 Gln Ser Ser Phe Thr Gly Leu Leu Lys Arg Met Glu Gln Arg Gly
                 230                 235                 240

 Val Ile Lys Arg Val Thr Leu Gln Ser Glu Ala Glu Ser Cys Glu
                 245                 250                 255

 Gly Lys Pro Asp Cys Val Thr Ser Lys Lys Arg Leu Val Pro Pro
                 260                 265                 270

 Leu His Pro Leu Leu Arg Ile Ala Thr Thr Glu Val Phe Lys Asp
                 275                 280                 285

 Pro Ala Asp Cys His Pro Ser Ser Phe Met Gly His Arg Val Tyr
                 290                 295                 300

 Pro Val Ala Lys Asp Thr Ser Pro Phe Gln Pro Asn Pro Pro Ala
                 305                 310                 315

 Glu Gly Pro Ile Val Glu Ala Leu Glu His Ser Lys Arg Gly Asn
                 320                 325                 330

 Thr Thr Ser Pro Leu Asp Ser Thr Ser Lys Glu Met Glu Val Met
                 335                 340                 345

 Gly Cys Arg Phe Tyr His Ala Ala Ser Ile Ala Ala Arg Ala Ala
                 350                 355                 360

 Ser Tyr Met Ala Tyr Met Thr Gln Tyr Gln Arg Lys Leu Trp Glu
                 365                 370                 375

 Asp Met Glu Asp Leu Val His Asp Pro Glu Phe Asp Arg Gly Lys
                 380                 385                 390

 Ala Arg Cys Ile Ile Ser Asp Gly Met Asp Ala Gly Leu Trp Gln
                 395                 400                 405

 Leu Cys Thr Thr Arg Asp Ile Met Asp Ser Val Val Arg Val Met
                 410                 415                 420

 Ala Met Ala Ile Asp Tyr Arg Arg Gln Ala Trp Leu Arg Leu Thr
                 425                 430                 435

 Ser Leu Thr Lys Lys Thr Gln Glu Lys Ile Ser His Leu Pro Phe
                 440                 445                 450

 Asp Gly Thr Ser Leu Phe Gly Gln Asp Val Lys Ala Val Val Ala
                 455                 460                 465

 Glu Asp Asn Asn Ile Lys Glu Asn Asp Tyr Lys Asp His Lys Tyr
                 470                 475                 480

 Tyr Asn Gln His Arg Tyr Phe Tyr Ser His Asp Gln Lys Ala His
                 485                 490                 495

 Tyr His Asn Arg Gly Tyr Ser Lys Gly Asp Trp Tyr Lys Pro Arg
                 500                 505                 510

 Asn His Pro Tyr Arg Tyr Arg Lys Lys Gly Asp Ser Pro Glu Arg
                 515                 520                 525

 His Gly Tyr Lys Asn
                 530

<210> 6291
<211> 3479
<212> DNA
<213> Homo sapien

<400> 6291
 tgaaagaggg aatcgtgtct tactcatctt tgtatcccca gtgtctagca 50

 gttcctgata catagtttta gctgaatttt gggacatggc cactgcttca 100

 ccaaggtctg atactagtaa taaccacagt ggaaggttgc agttacaggt 150

 aactgtttct agtgccaaac ttaaaagaaa aaagaactgg ttcggaacag 200

 caatatatac agaagtagtt gtagatggag aaattacgaa aacagcaaaa 250

 tccagtagtt cttctaatcc aaaatgggat gaacagctaa ctgtaaatgt 300

 tacgccacag actacattgg aatttcaagt ttggagccat cgcactttaa 350

 aagcagatgc tttattagga aaagcaacga tagatttgaa acaagctctg 400

 ttgatacaca atagaaaatt ggaaagagtg aaagaacaat taaaactttc 450

 cttggaaaac aagaatggca tagcacaaac tggtgaattg acagttgtgc 500

 ttgatggatt ggtgattgag caagaaaata taacaaactg cagctcatct 550

 ccaaccatag aaatacagga aaatggtgat gccttacatg aaaatggaga 600

 gccttcagca aggacaactg ccaggttggc tgttgaaggc acgaatggaa 650

 tagataatca tgtacctaca agcactctag tccaaaactc atgctgctcg 700

 tatgtagtta atggagacaa cacaccttca tctccgtctc aggttgctgc 750

 cagacccaaa aatacaccag ctccaaaacc actcgcatct gagcctgccg 800

 atgacactgt taatggagaa tcatcctcat ttgcaccaac tgataatgcg 850

 tctgtcacgg gtactccagt agtgtctgaa gaaaatgcct tgtctccaaa 900

 ttgcactagt actactgttg aagatcctcc agttcaagaa atactgactt 950

 cctcagaaaa caatgaatgt attccttcta ccagtgcaga attggaatct 1000

 gaagctagaa gtatattaga gcctgacacc tctaattcta gaagtagttc 1050

 tgcttttgaa gcagccaaat caagacagcc agatgggtgt atggatcctg 1100

 tacggcagca gtctgggaat gccaacacag aaaccttgcc atcagggtgg 1150

 gaacaaagaa aagatcctca tggtagaacc tattatgtgg atcataatac 1200

 tcgaactacc acatgggaga gaccacaacc tttacctcca ggttgggaaa 1250

 gaagagttga tgatcgtaga agagtttatt atgtggatca taacaccaga 1300

 acaacaacgt ggcagcggcc taccatggaa tctgtccgaa attttgaaca 1350

 gtggcaatct cagcggaacc aattgcaggg agctatgcaa cagtttaacc 1400

 aacgatacct ctattcggct tcaatgttag ctgcagaaaa tgacccttat 1450

 ggacctttgc caccaggctg ggaaaaaaga gtggattcaa cagacagggt 1500

 ttactttgtg aatcataaca caaaaacaac ccagtgggaa gatccaagaa 1550

 ctcaaggctt acagaatgaa gaacccctgc cagaaggctg ggaaattaga 1600

 tatactcgtg aaggtgtaag gtactttgtt gatcataaca caagaacaac 1650

 aacattcaaa gatcctcgca atgggaagtc atctgtaact aaaggtggtc 1700

 cacaaattgc ttatgaacgc ggctttaggt ggaagcttgc tcacttccgt 1750

 tatttgtgcc agtctaatgc actacctagt catgtaaaga tcaatgtgtc 1800

 ccggcagaca ttgtttgaag attccttcca acagattatg gcattaaaac 1850

 cctatgactt gaggaggcgc ttatatgtaa tatttagagg agaagaagga 1900

 cttgattatg gtggcctagc gagagaatgg tttttcttgc tttcacatga 1950

 agttttgaac ccaatgtatt gcttatttga gtatgcgggc aagaacaact 2000

 attgtctgca gataaatcca gcatcaacca ttaatccaga ccatctttca 2050

 tacttctgtt tcattggtcg ttttattgcc atggcactat ttcatggaaa 2100

 gtttatcgat actggtttct ctttaccatt ctacaagcgt atgttaagta 2150

 aaaaacttac tattaaggat ttggaatcta ttgatactga attttataac 2200

 tcccttatct ggataagaga taacaacatt gaagaatgtg gcttagaaat 2250

 gtacttttct gttgacatgg agattttggg aaaagttact tcacatgacc 2300

 tgaagttggg aggttccaat attctggtga ctgaggagaa caaagatgaa 2350

 tatattggtt taatgacaga atggcgtttt tctcgaggag tacaagaaca 2400

 gaccaaagct ttccttgatg gttttaatga agttgttcct cttcagtggc 2450

 tacagtactt cgatgaaaaa gaattagagg ttatgttgtg tggcatgcag 2500

 gaggttgact tggcagattg gcagagaaat actgtttatc gacattatac 2550

 aagaaacagc aagcaaatca tttggttttg gcagtttgtg aaagagacag 2600

 acaatgaagt aagaatgcga ctattgcagt tcgtcactgg aacctgccgt 2650

 ttacctctag gaggatttgc tgagctcatg ggaagtaatg ggcctcaaaa 2700

 gttttgcatt gaaaaagttg gcaaagacac ttggttacca agaagccata 2750

 catgttttaa tcgcttggat ctaccaccat ataagagtta tgaacaacta 2800

 aaggaaaaac ttctttttgc aatagaagag acagagggat ttggacaaga 2850

 atgaatgtgg cttcttattt tggaggagct cttgcattta aataccccag 2900

 ccaagaaaaa ttgcacagat agtgtatata agctgttcat tctgtacagt 2950

 gaattttccg aacctctcaa agtatgtttt ccgttcttcc acagaaatat 3000

 gcaaaacagt tcatcctttt ctactttatt tattgttccc ttgaaatgac 3050

 tgaccaggaa aaagatcatc cttaaatttt gaagcaagtg agagacttta 3100

 ttaaaaatac atatatatct atataaacat atatgatagt ggctctagtt 3150

 ttatagagct ccaagtgtat taaacatgac agccattcat tcataaagat 3200

 ctggatttgc tttaccttgt taatattatc taggggaaaa agtgcaaatt 3250

 gctccatgtt cttctctccc ttatgtaaca tctcctgagg gtgtttagtt 3300

 gcatggctgt tcagaaaggt attaagggct taggccaaat cttactttga 3350

 gtatgttaaa aaaaaaaaaa tgctgctggc ttttctgaag acaggtgctt 3400

 gaacttgtca gtttgtttta aataaataca atagttgaaa atttaaaaaa 3450

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 3479

<210> 6292
<211> 922
<212> PRT
<213> Homo sapien

<400> 6292
 Met Ala Thr Ala Ser Pro Arg Ser Asp Thr Ser Asn Asn His Ser
   1               5                  10                  15

 Gly Arg Leu Gln Leu Gln Val Thr Val Ser Ser Ala Lys Leu Lys
                  20                  25                  30

 Arg Lys Lys Asn Trp Phe Gly Thr Ala Ile Tyr Thr Glu Val Val
                  35                  40                  45

 Val Asp Gly Glu Ile Thr Lys Thr Ala Lys Ser Ser Ser Ser Ser
                  50                  55                  60

 Asn Pro Lys Trp Asp Glu Gln Leu Thr Val Asn Val Thr Pro Gln
                  65                  70                  75

 Thr Thr Leu Glu Phe Gln Val Trp Ser His Arg Thr Leu Lys Ala
                  80                  85                  90

 Asp Ala Leu Leu Gly Lys Ala Thr Ile Asp Leu Lys Gln Ala Leu
                  95                 100                 105

 Leu Ile His Asn Arg Lys Leu Glu Arg Val Lys Glu Gln Leu Lys
                 110                 115                 120

 Leu Ser Leu Glu Asn Lys Asn Gly Ile Ala Gln Thr Gly Glu Leu
                 125                 130                 135

 Thr Val Val Leu Asp Gly Leu Val Ile Glu Gln Glu Asn Ile Thr
                 140                 145                 150

 Asn Cys Ser Ser Ser Pro Thr Ile Glu Ile Gln Glu Asn Gly Asp
                 155                 160                 165

 Ala Leu His Glu Asn Gly Glu Pro Ser Ala Arg Thr Thr Ala Arg
                 170                 175                 180

 Leu Ala Val Glu Gly Thr Asn Gly Ile Asp Asn His Val Pro Thr
                 185                 190                 195

 Ser Thr Leu Val Gln Asn Ser Cys Cys Ser Tyr Val Val Asn Gly
                 200                 205                 210

 Asp Asn Thr Pro Ser Ser Pro Ser Gln Val Ala Ala Arg Pro Lys
                 215                 220                 225

 Asn Thr Pro Ala Pro Lys Pro Leu Ala Ser Glu Pro Ala Asp Asp
                 230                 235                 240

 Thr Val Asn Gly Glu Ser Ser Ser Phe Ala Pro Thr Asp Asn Ala
                 245                 250                 255

 Ser Val Thr Gly Thr Pro Val Val Ser Glu Glu Asn Ala Leu Ser
                 260                 265                 270

 Pro Asn Cys Thr Ser Thr Thr Val Glu Asp Pro Pro Val Gln Glu
                 275                 280                 285

 Ile Leu Thr Ser Ser Glu Asn Asn Glu Cys Ile Pro Ser Thr Ser
                 290                 295                 300

 Ala Glu Leu Glu Ser Glu Ala Arg Ser Ile Leu Glu Pro Asp Thr
                 305                 310                 315

 Ser Asn Ser Arg Ser Ser Ser Ala Phe Glu Ala Ala Lys Ser Arg
                 320                 325                 330

 Gln Pro Asp Gly Cys Met Asp Pro Val Arg Gln Gln Ser Gly Asn
                 335                 340                 345

 Ala Asn Thr Glu Thr Leu Pro Ser Gly Trp Glu Gln Arg Lys Asp
                 350                 355                 360

 Pro His Gly Arg Thr Tyr Tyr Val Asp His Asn Thr Arg Thr Thr
                 365                 370                 375

 Thr Trp Glu Arg Pro Gln Pro Leu Pro Pro Gly Trp Glu Arg Arg
                 380                 385                 390

 Val Asp Asp Arg Arg Arg Val Tyr Tyr Val Asp His Asn Thr Arg
                 395                 400                 405

 Thr Thr Thr Trp Gln Arg Pro Thr Met Glu Ser Val Arg Asn Phe
                 410                 415                 420

 Glu Gln Trp Gln Ser Gln Arg Asn Gln Leu Gln Gly Ala Met Gln
                 425                 430                 435

 Gln Phe Asn Gln Arg Tyr Leu Tyr Ser Ala Ser Met Leu Ala Ala
                 440                 445                 450

 Glu Asn Asp Pro Tyr Gly Pro Leu Pro Pro Gly Trp Glu Lys Arg
                 455                 460                 465

 Val Asp Ser Thr Asp Arg Val Tyr Phe Val Asn His Asn Thr Lys
                 470                 475                 480

 Thr Thr Gln Trp Glu Asp Pro Arg Thr Gln Gly Leu Gln Asn Glu
                 485                 490                 495

 Glu Pro Leu Pro Glu Gly Trp Glu Ile Arg Tyr Thr Arg Glu Gly
                 500                 505                 510

 Val Arg Tyr Phe Val Asp His Asn Thr Arg Thr Thr Thr Phe Lys
                 515                 520                 525

 Asp Pro Arg Asn Gly Lys Ser Ser Val Thr Lys Gly Gly Pro Gln
                 530                 535                 540

 Ile Ala Tyr Glu Arg Gly Phe Arg Trp Lys Leu Ala His Phe Arg
                 545                 550                 555

 Tyr Leu Cys Gln Ser Asn Ala Leu Pro Ser His Val Lys Ile Asn
                 560                 565                 570

 Val Ser Arg Gln Thr Leu Phe Glu Asp Ser Phe Gln Gln Ile Met
                 575                 580                 585

 Ala Leu Lys Pro Tyr Asp Leu Arg Arg Arg Leu Tyr Val Ile Phe
                 590                 595                 600

 Arg Gly Glu Glu Gly Leu Asp Tyr Gly Gly Leu Ala Arg Glu Trp
                 605                 610                 615

 Phe Phe Leu Leu Ser His Glu Val Leu Asn Pro Met Tyr Cys Leu
                 620                 625                 630

 Phe Glu Tyr Ala Gly Lys Asn Asn Tyr Cys Leu Gln Ile Asn Pro
                 635                 640                 645

 Ala Ser Thr Ile Asn Pro Asp His Leu Ser Tyr Phe Cys Phe Ile
                 650                 655                 660

 Gly Arg Phe Ile Ala Met Ala Leu Phe His Gly Lys Phe Ile Asp
                 665                 670                 675

 Thr Gly Phe Ser Leu Pro Phe Tyr Lys Arg Met Leu Ser Lys Lys
                 680                 685                 690

 Leu Thr Ile Lys Asp Leu Glu Ser Ile Asp Thr Glu Phe Tyr Asn
                 695                 700                 705

 Ser Leu Ile Trp Ile Arg Asp Asn Asn Ile Glu Glu Cys Gly Leu
                 710                 715                 720

 Glu Met Tyr Phe Ser Val Asp Met Glu Ile Leu Gly Lys Val Thr
                 725                 730                 735

 Ser His Asp Leu Lys Leu Gly Gly Ser Asn Ile Leu Val Thr Glu
                 740                 745                 750

 Glu Asn Lys Asp Glu Tyr Ile Gly Leu Met Thr Glu Trp Arg Phe
                 755                 760                 765

 Ser Arg Gly Val Gln Glu Gln Thr Lys Ala Phe Leu Asp Gly Phe
                 770                 775                 780

 Asn Glu Val Val Pro Leu Gln Trp Leu Gln Tyr Phe Asp Glu Lys
                 785                 790                 795

 Glu Leu Glu Val Met Leu Cys Gly Met Gln Glu Val Asp Leu Ala
                 800                 805                 810

 Asp Trp Gln Arg Asn Thr Val Tyr Arg His Tyr Thr Arg Asn Ser
                 815                 820                 825

 Lys Gln Ile Ile Trp Phe Trp Gln Phe Val Lys Glu Thr Asp Asn
                 830                 835                 840

 Glu Val Arg Met Arg Leu Leu Gln Phe Val Thr Gly Thr Cys Arg
                 845                 850                 855

 Leu Pro Leu Gly Gly Phe Ala Glu Leu Met Gly Ser Asn Gly Pro
                 860                 865                 870

 Gln Lys Phe Cys Ile Glu Lys Val Gly Lys Asp Thr Trp Leu Pro
                 875                 880                 885

 Arg Ser His Thr Cys Phe Asn Arg Leu Asp Leu Pro Pro Tyr Lys
                 890                 895                 900

 Ser Tyr Glu Gln Leu Lys Glu Lys Leu Leu Phe Ala Ile Glu Glu
                 905                 910                 915

 Thr Glu Gly Phe Gly Gln Glu
                 920

<210> 6293
<211> 2375
<212> DNA
<213> Homo sapien

<400> 6293
 taatttaaac cagtgtttgt gcggttctga ttcatctgct gtggttcccg 50

 aagcttgaga tctaaggagt acagggtctt ttgtgatgac aatatgacta 100

 atagtaaagg aagatctatt accgataaaa caagtggtgg tccaagtagt 150

 ggaggaggtt ttgtagattg gactttacgt ttaaacacaa ttcaatccga 200

 caagttttta aatttactct tgagtatggt tccagtgatt taccagaaaa 250

 accaagaaga caggcacaaa aaagcaaacg gcatttggca agatggatat 300

 caactgcagt acagactttt agtaatagat ctgagcaaca catggagtat 350

 cacagtttct cagagcagtc ttttcatgcc aataatgggc acgcatcatc 400

 aagctgcagc caaaagtatg atgactatgc caattgtaat tactgtgatg 450

 gaagggagac ttcagaaacc actgccatgt tacaagatga agatatatct 500

 agtgatggtg atgaagatgc tattgtagaa gtgaccccaa aattaccaaa 550

 ggaatccagt ggcatcatgg cattgcaaat acttgtgccc tttttgctag 600

 ctggttttgg aacagtttca gctggcatgg tactggatat agtacagcac 650

 tgggaggtgt tcagaaaagt tacagaagtt ttcattttag tccctgcact 700

 tcttggtctc aaagggaact tggaaatgac attggcatcc agattatcca 750

 ctgcagtaaa tattgggaag atggattcac ccattgaaaa gtggaaccta 800

 ataattggca acttggcttt aaagcaggtt caggcaacag tagtgggttt 850

 tctagcagct gtggcagcaa ttatattggg ctggattcca gaaggaaaat 900

 attaccttga tcattccata cttctgtgct ctagcagtgt ggcaactgcc 950

 ttcattgcat ctcttctgca gggaataata atggttgggg ttatcgttgg 1000

 ttcaaagaag actggtataa atcctgataa tgttgctaca cccattgctg 1050

 ctagttttgg cgaccttata actcttgcca tattggcttg gataagtcag 1100

 ggcttatact cctgtcttga gacctattac tacatttctc cattagttgg 1150

 tgtatttttc ttggctctaa cccctatttg gattataata gctgccaaac 1200

 atccagccac aagaacagtt ctccactcag gctgggagcc tgtcataaca 1250

 gctatggtta taagtagcat tgggggcctt attctggaca caactgtatc 1300

 agacccaaac ttggttggga ttgttgttta cacgccagtt attaatggta 1350

 ttggtggtaa tttggtggcc attcaggcta gcaggatttc tacctacctc 1400

 catttacata gcattccagg agaattgcct gatgaaccca aaggttgtta 1450

 ctacccattt agaactttct ttggtccagg agtaaataat aagtctgctc 1500

 aagttctact gcttttagtg attcctggac atttaatttt cctctacact 1550

 attcatttga tgaaaagtgg tcatacttct ttaactataa tcttcatagt 1600

 agtgtattta tttggcgctg tgttacaggt atttaccttg ctgtggattg 1650

 ctgactggat ggtccatcac ttctggagga aaggaaagga cccggatagt 1700

 ttctccatcc cctacctaac agcattgggt gatctgctcg ggacagctct 1750

 gttagcctta agttttcatt ttctttggct tattggagat cgagatggag 1800

 atgttggaga ctaataaatt ctacaaactg ctctcaagtt accaaggaag 1850

 aaaatacacg acaaccactt atggctcttt ttcaaaactc ttaaatcagt 1900

 agtttgactt ttgccagggt aatcttcagt tggccctgat tcaattaaat 1950

 ggccttaatt tttttttaag gaatttgtgt caaaaccaga atgaagagta 2000

 ttcgtgctgc ttttcataga ataaatgata atttgacata gacatagata 2050

 taagttccag ctctgaaatt aattaggaaa gaatatagga tgtttacagt 2100

 gaataatttt aaaaccacaa acatagcaga aatgtacttt attattaaat 2150

 ttgtaatgca ggattagaag aagcagagct ctagtttagc ctttcttgtc 2200

 tcacagatgt gctgtatccc aggcatacta taaaacgaag agtgcccaac 2250

 caagctttga atcgtattaa caatgcccac ctctatgcta gctgaggata 2300

 aatttaccag ttgctcatat ttaaactgac ctaaatatgt tttgctgagc 2350

 ataagataaa ctcactttta cctcc 2375

<210> 6294
<211> 490
<212> PRT
<213> Homo sapien

<400> 6294
 Met Glu Tyr His Ser Phe Ser Glu Gln Ser Phe His Ala Asn Asn
   1               5                  10                  15

 Gly His Ala Ser Ser Ser Cys Ser Gln Lys Tyr Asp Asp Tyr Ala
                  20                  25                  30

 Asn Cys Asn Tyr Cys Asp Gly Arg Glu Thr Ser Glu Thr Thr Ala
                  35                  40                  45

 Met Leu Gln Asp Glu Asp Ile Ser Ser Asp Gly Asp Glu Asp Ala
                  50                  55                  60

 Ile Val Glu Val Thr Pro Lys Leu Pro Lys Glu Ser Ser Gly Ile
                  65                  70                  75

 Met Ala Leu Gln Ile Leu Val Pro Phe Leu Leu Ala Gly Phe Gly
                  80                  85                  90

 Thr Val Ser Ala Gly Met Val Leu Asp Ile Val Gln His Trp Glu
                  95                 100                 105

 Val Phe Arg Lys Val Thr Glu Val Phe Ile Leu Val Pro Ala Leu
                 110                 115                 120

 Leu Gly Leu Lys Gly Asn Leu Glu Met Thr Leu Ala Ser Arg Leu
                 125                 130                 135

 Ser Thr Ala Val Asn Ile Gly Lys Met Asp Ser Pro Ile Glu Lys
                 140                 145                 150

 Trp Asn Leu Ile Ile Gly Asn Leu Ala Leu Lys Gln Val Gln Ala
                 155                 160                 165

 Thr Val Val Gly Phe Leu Ala Ala Val Ala Ala Ile Ile Leu Gly
                 170                 175                 180

 Trp Ile Pro Glu Gly Lys Tyr Tyr Leu Asp His Ser Ile Leu Leu
                 185                 190                 195

 Cys Ser Ser Ser Val Ala Thr Ala Phe Ile Ala Ser Leu Leu Gln
                 200                 205                 210

 Gly Ile Ile Met Val Gly Val Ile Val Gly Ser Lys Lys Thr Gly
                 215                 220                 225

 Ile Asn Pro Asp Asn Val Ala Thr Pro Ile Ala Ala Ser Phe Gly
                 230                 235                 240

 Asp Leu Ile Thr Leu Ala Ile Leu Ala Trp Ile Ser Gln Gly Leu
                 245                 250                 255

 Tyr Ser Cys Leu Glu Thr Tyr Tyr Tyr Ile Ser Pro Leu Val Gly
                 260                 265                 270

 Val Phe Phe Leu Ala Leu Thr Pro Ile Trp Ile Ile Ile Ala Ala
                 275                 280                 285

 Lys His Pro Ala Thr Arg Thr Val Leu His Ser Gly Trp Glu Pro
                 290                 295                 300

 Val Ile Thr Ala Met Val Ile Ser Ser Ile Gly Gly Leu Ile Leu
                 305                 310                 315

 Asp Thr Thr Val Ser Asp Pro Asn Leu Val Gly Ile Val Val Tyr
                 320                 325                 330

 Thr Pro Val Ile Asn Gly Ile Gly Gly Asn Leu Val Ala Ile Gln
                 335                 340                 345

 Ala Ser Arg Ile Ser Thr Tyr Leu His Leu His Ser Ile Pro Gly
                 350                 355                 360

 Glu Leu Pro Asp Glu Pro Lys Gly Cys Tyr Tyr Pro Phe Arg Thr
                 365                 370                 375

 Phe Phe Gly Pro Gly Val Asn Asn Lys Ser Ala Gln Val Leu Leu
                 380                 385                 390

 Leu Leu Val Ile Pro Gly His Leu Ile Phe Leu Tyr Thr Ile His
                 395                 400                 405

 Leu Met Lys Ser Gly His Thr Ser Leu Thr Ile Ile Phe Ile Val
                 410                 415                 420

 Val Tyr Leu Phe Gly Ala Val Leu Gln Val Phe Thr Leu Leu Trp
                 425                 430                 435

 Ile Ala Asp Trp Met Val His His Phe Trp Arg Lys Gly Lys Asp
                 440                 445                 450

 Pro Asp Ser Phe Ser Ile Pro Tyr Leu Thr Ala Leu Gly Asp Leu
                 455                 460                 465

 Leu Gly Thr Ala Leu Leu Ala Leu Ser Phe His Phe Leu Trp Leu
                 470                 475                 480

 Ile Gly Asp Arg Asp Gly Asp Val Gly Asp
                 485                 490

<210> 6295
<211> 2071
<212> DNA
<213> Homo sapien

<400> 6295
 catcaccctt tttaacattg tttacacatc actgcctgtt ttagccatgg 50

 ggatttttga ccaggatgtg agtgaccaga acagcgtgga ctgtccccag 100

 ctctacaaac caggacagct gaatctgctt tttaacaagc gtaaattttc 150

 catttgcgtg ttgcatggaa tctacacctc attagtcctt ttcttcatcc 200

 cctatggggc cttttacaac gtggctggag aagatgggca acatattgct 250

 gactaccagt cctctgcagt tacatggcca catctttggt cattgtggtc 300

 agtgtgcaga tagccttgga taccagttac tggactttca ttaatcacgt 350

 cttcatctgg gggagcattg ccatttattt ctccatttta tttacaatgc 400

 acagtaatgg catctttggc atcttcccaa accagtttcc atttgttggt 450

 aatgcacgac attccctgac ccagaagtgc atctggcttg taattctctt 500

 aacaacagtg gcttcagtta tgccagtggt ggcattcaga tttttgaagg 550

 tggatttata cccaaccctg agtgatcaga tccgccggtg gcagaaggct 600

 caaaagaagg caaggcctcc aagtagccga aggcctcgga cccgcaggtc 650

 aagctcaaga aggtctggat atgcttttgc tcaccaagaa ggctatggag 700

 agcttatcac atctggaaaa aatatgcgag ctaaaaatcc acccccaaca 750

 tcagggctgg aaaagacaca ttataatagc actagctgga ttgaaaattt 800

 atgtaagaaa accacagaca ccgtgagcag ctttagccag gataaaacag 850

 tgaaactgtg agtcaatatg aatttaaacc acgtagttat cttttcactt 900

 caggtggagc tgaaattctg ctggctccag agtttgagat ttgaggcaag 950

 aggtggggca ggcagattgc ctcacttaac ttaaatctgc ggcagacaac 1000

 tgccagtgcc catcaaacag gagtgtgcgc tatggaaaac caggccagag 1050

 ggtcactgtc tggtttgtga tttggtggac aaaacactcg ctgttacaag 1100

 tacagatttt tttttttttt aaatcaacct agataccaat tgacctgaac 1150

 tttagaatct tatttatgga gaaaaacttg taaagctgca tattcactga 1200

 atggatcctc aggcggataa aagggtgcat tttaaaggta tatatccaag 1250

 ctgaaaagca tgcctattga cagataaaca tgtatctgta agatcagcct 1300

 ttcccaaggt atacttttaa aatttaaagc gtgtactgtg ttgctttcag 1350

 actgagttgc atgtcactct ttagtcttga tatctacctg tctgttcagc 1400

 caggacaaca aatggcttcc aagcctgaag aatacaaaag tgtgcttgtg 1450

 tttctcattt ttataccagt ctagggacaa aggagactga acatctttgc 1500

 agcaggatag gctggtaatt tgatcaaatt tattcaaaaa gctctcagtc 1550

 tgtgtcatgt aaggacatgc ttatgaaatg tgagagaggc tcgccactaa 1600

 gtattctaaa tacttttcaa tggcttttct aacaacctca gtagtaattt 1650

 gctgagcatc atccagacca ttaatagaat cagcaaagca ctggaatttc 1700

 acactttaat gataatattc cacatagtct atgggcaaat attttcaaca 1750

 tttccaattt ttaaagcttc agaattgaag ccaaacaaat taataaataa 1800

 ttgttttaat tactatttaa aaactcaggt ttagattgtt taaaattagt 1850

 tgcttttgat actcagctgt catgtttata attcaaacat gtagtaaaca 1900

 tatgtaggta aggttgtttt tttggagatg ttgcagctca aatttcagtc 1950

 cacatatgaa tcatcagtgt attttccata aagtgattcg ggcatatttg 2000

 tgtgaaaacc tcagttctgt cacttcttac ctctataaac ttggacgata 2050

 atgaaaaaaa aaaaaaaaaa a 2071

<210> 6296
<211> 195
<212> PRT
<213> Homo sapien

<400> 6296
 Met Ala Thr Ser Leu Val Ile Val Val Ser Val Gln Ile Ala Leu
   1               5                  10                  15

 Asp Thr Ser Tyr Trp Thr Phe Ile Asn His Val Phe Ile Trp Gly
                  20                  25                  30

 Ser Ile Ala Ile Tyr Phe Ser Ile Leu Phe Thr Met His Ser Asn
                  35                  40                  45

 Gly Ile Phe Gly Ile Phe Pro Asn Gln Phe Pro Phe Val Gly Asn
                  50                  55                  60

 Ala Arg His Ser Leu Thr Gln Lys Cys Ile Trp Leu Val Ile Leu
                  65                  70                  75

 Leu Thr Thr Val Ala Ser Val Met Pro Val Val Ala Phe Arg Phe
                  80                  85                  90

 Leu Lys Val Asp Leu Tyr Pro Thr Leu Ser Asp Gln Ile Arg Arg
                  95                 100                 105

 Trp Gln Lys Ala Gln Lys Lys Ala Arg Pro Pro Ser Ser Arg Arg
                 110                 115                 120

 Pro Arg Thr Arg Arg Ser Ser Ser Arg Arg Ser Gly Tyr Ala Phe
                 125                 130                 135

 Ala His Gln Glu Gly Tyr Gly Glu Leu Ile Thr Ser Gly Lys Asn
                 140                 145                 150

 Met Arg Ala Lys Asn Pro Pro Pro Thr Ser Gly Leu Glu Lys Thr
                 155                 160                 165

 His Tyr Asn Ser Thr Ser Trp Ile Glu Asn Leu Cys Lys Lys Thr
                 170                 175                 180

 Thr Asp Thr Val Ser Ser Phe Ser Gln Asp Lys Thr Val Lys Leu
                 185                 190                 195

<210> 6297
<211> 1632
<212> DNA
<213> Homo sapien

<400> 6297
 atagatacta gattgtattg aattctgttt taattattct ctaggtaagt 50

 atgttttagg attaaatacc ttttacagat actgaaagtg cctccttttg 100

 tggtgtaaaa aacaaattat ggtgcaaaaa gtaatcacta gattgaaata 150

 catgaaggtt ttttgctttt tgacatacga aaatgtcaag agaaaggcca 200

 aagatttgta ctttttcact tacaaagcac tcctttttcc cttaaacttc 250

 tttctgtcaa attagattta atgagagagt actattttta aggagctatc 300

 tgtttatgta gaatgatttt gttaagagta atgtaaacta ttattgagta 350

 gaggcctaaa gaggactgtg ccatttttgc tatttaaagg aatcacaaat 400

 gatcatactt aagtgagcaa aaatgacaag ttttactagc taagtagaga 450

 aataaatctc aaatgcagcg ctacaatttt cattatctta agtacattgt 500

 acatttctac agaacctgtg attattctcg catgataagg atggtacttg 550

 catatggtga attactactg ttgacagttt ccgcagaaat cctatttcag 600

 tggaccaaca ttgtggcatg gcagcaaatg ccaacatttt gtggaatagc 650

 agcaaatcta caagagaccc tggttggttt ttcgttttgt tttctttgtt 700

 ttttccccct tctcctgaat cagcagggat ggaaggaggg tagggaagtt 750

 atgaattact ccttccagta gtagctctga agtgtcacat ttaatatcag 800

 ttttttttaa acatgattct agttaaatgt agaagagaga agaaagagga 850

 agtgttcact tttttaatac actgatttag aaatttgatg tcttatatca 900

 gtagttctga ggtattgata gcttgcttta tttctgcctt tacgttgaca 950

 gtgttgaagc agggtgaata actagggcat atattttttt ttttttttgt 1000

 aagctgtttc atgatgtttt ctttggaatt tccggataag ttcaggaaaa 1050

 cattctgcat gttgtatcta gtctgatgta cttatccatc tcattacaaa 1100

 caaaaacaca cagaactgca tttgtagctc tgtaatcctt gaatacggaa 1150

 gtaaattttc ttctttcctg actttgacat tgtagctata ctgtttccat 1200

 ttttgttttt acaaatcctt tgggtctaat tctgtgagcc tacctatagc 1250

 actggattaa aatgtctgca tcatttcttt agttatccag ttaactttaa 1300

 aactgttgta aaagtgtaaa ccagcccatg acaggttttt gtacatgtta 1350

 aagaacttca ttgttcagtt ttcatgatta ttgtgtaagg aagactgatg 1400

 tagatgttct gtgctgtcct ggaccatgtt aattacactt acgacgtatt 1450

 ttagttccac atcacaatga tttgtcccca gtgacccttt tatcctttct 1500

 aggcacattt cttgttgttg ttgttgttgc agttcccctt tgcattgtat 1550

 tgctttgaca actgtaattt gaatcagatc tgaaagaggt ccagaataaa 1600

 atatattttg atattaaaaa aagaaaaaaa at 1632

<210> 6298
<211> 102
<212> PRT
<213> Homo sapien

<400> 6298
 Met Gln Arg Tyr Asn Phe His Tyr Leu Lys Tyr Ile Val His Phe
   1               5                  10                  15

 Tyr Arg Thr Cys Asp Tyr Ser Arg Met Ile Arg Met Val Leu Ala
                  20                  25                  30

 Tyr Gly Glu Leu Leu Leu Leu Thr Val Ser Ala Glu Ile Leu Phe
                  35                  40                  45

 Gln Trp Thr Asn Ile Val Ala Trp Gln Gln Met Pro Thr Phe Cys
                  50                  55                  60

 Gly Ile Ala Ala Asn Leu Gln Glu Thr Leu Val Gly Phe Ser Phe
                  65                  70                  75

 Cys Phe Leu Cys Phe Phe Pro Leu Leu Leu Asn Gln Gln Gly Trp
                  80                  85                  90

 Lys Glu Gly Arg Glu Val Met Asn Tyr Ser Phe Gln
                  95                 100

<210> 6299
<211> 2530
<212> DNA
<213> Homo sapien

<400> 6299
 ctaaagtgga gcccagcggc gggtgtgaga gtccgtaagg agcagcttcc 50

 aggatcctga gatccggagc agccggggtc ggagcggctc ctcaagagtt 100

 actgatctat gaaatggcag agaatggaaa aaattgtgac cagagacgtg 150

 tagcaatgaa caaggaacat cataatggaa atttcacaga cccctcttca 200

 gtgaatgaaa agaagaggag ggagcgggaa gaaaggcaga atattgtcct 250

 gtggagacag ccgctcatta ccttgcagta tttttctctg gaaatccttg 300

 taatcttgaa ggaatggacc tcaaaattat ggcatcgtca aagcattgtg 350

 gtgtcttttt tactgctgct tgctgtgctt atagctacgt attatgttga 400

 aggagtgcat caacagtatg tgcaacgtat agagaaacag tttcttttgt 450

 atgcctactg gataggctta ggaattttgt cttctgttgg gcttggaaca 500

 gggctgcaca cctttctgct ttatctgggt ccacatatag cctcagttac 550

 attagctgct tatgaatgca attcagttaa ttttcccgaa ccaccctatc 600

 ctgatcagat tatttgtcca gatgaagagg gcactgaagg aaccatttct 650

 ttgtggagta tcatctcaaa agttaggatt gaagcctgca tgtggggtat 700

 cggtacagca atcggagagc tgcctccata tttcatggcc agagcagctc 750

 gcctctcagg tgctgaacca gatgatgaag agtatcagga atttgaagag 800

 atgctggaac atgcagagtc tgcacaagac tttgcctccc gggccaaact 850

 ggcagttcaa aaactagtac agaaagttgg attttttgga attttggcct 900

 gtgcttcaat tccaaatcct ttatttgatc tggctggaat aacgtgtgga 950

 cactttctgg tacctttttg gaccttcttt ggtgcaaccc taattggaaa 1000

 agcaataata aaaatgcata tccagaaaat ttttgttata ataacattca 1050

 gcaagcacat agtggagcaa atggtggctt tcattggtgc tgtccccggc 1100

 ataggtccat ctctgcagaa gccatttcag gagtacctgg aggctcaacg 1150

 gcagaagctt caccacaaaa gcgaaatggg cacaccacag ggagaaaact 1200

 ggttgtcctg gatgtttgaa aagttggtcg ttgtcatggt gtgttacttc 1250

 atcctatcta tcattaactc catggcacaa agttatgcca aacgaatcca 1300

 gcagcggttg aactcagagg agaaaactaa ataagtagag aaagttttaa 1350

 actgcagaaa ttggagtgga tgggttctgc cttaaattgg gaggactcca 1400

 agccgggaag gaaaattccc ttttccaacc tgtatcaatt tttacaactt 1450

 ttttcctgaa agcagtttag tccatacttt gcactgacat actttttcct 1500

 tctgtgctaa ggtaaggtat ccaccctcga tgcaatccac cttgtgtttt 1550

 cttagggtgg aatgtgatgt tcagcagcaa acttgcaaca gactggcctt 1600

 ctgtttgtta ctttcaaaag gcccacatga tacaattaga gaattcccac 1650

 cgcacaaaaa aagttcctaa gtatgttaaa tatgtcaagc tttttaggct 1700

 tgtcacaaat gattgctttg ttttcctaag tcatcaaaat gtatataaat 1750

 tatctagatt ggataacagt cttgcatgtt tatcatgtta caatttaata 1800

 ttccatcctg cccaaccctt cctctcccat cctcaaaaaa gggccatttt 1850

 atgatgcatt gcacaccctc tggggaaatt gatctttaaa ttttgagaca 1900

 gtataaggaa aatctggttg gtgtcttaca agtgagctga caccattttt 1950

 tattctgtgt atttagaatg aagtcttgaa aaaaacttta taaagacatc 2000

 tttaatcatt ccaaaattgt gtccgttttc ttgagcgttt tgatttttta 2050

 cttttagctt ataccagctg aatggcagcc ttgcctaatc cacctacaac 2100

 aagaatttct taagctttct tttatttgca tgagagagcc actaccaagg 2150

 catgttttgt tatgctgaaa ctgggctgct gcatactgct aaatggcacc 2200

 tctgggattg gcctacctgg ggatttcttg gtttgtgaaa acaggagagg 2250

 agaaatatct catacaagtg aaaggatact ggagagagaa attacccatt 2300

 tctaaaaaaa aaccacactc tgtcgtatct gtgttaatgt tttctagcat 2350

 gtactctggt ttcaacagac acaaatttat atgttaaccc agttttcttg 2400

 ccgttctgta agtgttttat tcttagtgtg atttttttcc attgggatgt 2450

 ttttgattga acttgttcat tttgttttgc ttgggaggaa aataaacaat 2500

 tttacttttt tccttaaaaa aaaaaaaaaa 2530

<210> 6300
<211> 406
<212> PRT
<213> Homo sapien

<400> 6300
 Met Ala Glu Asn Gly Lys Asn Cys Asp Gln Arg Arg Val Ala Met
   1               5                  10                  15

 Asn Lys Glu His His Asn Gly Asn Phe Thr Asp Pro Ser Ser Val
                  20                  25                  30

 Asn Glu Lys Lys Arg Arg Glu Arg Glu Glu Arg Gln Asn Ile Val
                  35                  40                  45

 Leu Trp Arg Gln Pro Leu Ile Thr Leu Gln Tyr Phe Ser Leu Glu
                  50                  55                  60

 Ile Leu Val Ile Leu Lys Glu Trp Thr Ser Lys Leu Trp His Arg
                  65                  70                  75

 Gln Ser Ile Val Val Ser Phe Leu Leu Leu Leu Ala Val Leu Ile
                  80                  85                  90

 Ala Thr Tyr Tyr Val Glu Gly Val His Gln Gln Tyr Val Gln Arg
                  95                 100                 105

 Ile Glu Lys Gln Phe Leu Leu Tyr Ala Tyr Trp Ile Gly Leu Gly
                 110                 115                 120

 Ile Leu Ser Ser Val Gly Leu Gly Thr Gly Leu His Thr Phe Leu
                 125                 130                 135

 Leu Tyr Leu Gly Pro His Ile Ala Ser Val Thr Leu Ala Ala Tyr
                 140                 145                 150

 Glu Cys Asn Ser Val Asn Phe Pro Glu Pro Pro Tyr Pro Asp Gln
                 155                 160                 165

 Ile Ile Cys Pro Asp Glu Glu Gly Thr Glu Gly Thr Ile Ser Leu
                 170                 175                 180

 Trp Ser Ile Ile Ser Lys Val Arg Ile Glu Ala Cys Met Trp Gly
                 185                 190                 195

 Ile Gly Thr Ala Ile Gly Glu Leu Pro Pro Tyr Phe Met Ala Arg
                 200                 205                 210

 Ala Ala Arg Leu Ser Gly Ala Glu Pro Asp Asp Glu Glu Tyr Gln
                 215                 220                 225

 Glu Phe Glu Glu Met Leu Glu His Ala Glu Ser Ala Gln Asp Phe
                 230                 235                 240

 Ala Ser Arg Ala Lys Leu Ala Val Gln Lys Leu Val Gln Lys Val
                 245                 250                 255

 Gly Phe Phe Gly Ile Leu Ala Cys Ala Ser Ile Pro Asn Pro Leu
                 260                 265                 270

 Phe Asp Leu Ala Gly Ile Thr Cys Gly His Phe Leu Val Pro Phe
                 275                 280                 285

 Trp Thr Phe Phe Gly Ala Thr Leu Ile Gly Lys Ala Ile Ile Lys
                 290                 295                 300

 Met His Ile Gln Lys Ile Phe Val Ile Ile Thr Phe Ser Lys His
                 305                 310                 315

 Ile Val Glu Gln Met Val Ala Phe Ile Gly Ala Val Pro Gly Ile
                 320                 325                 330

 Gly Pro Ser Leu Gln Lys Pro Phe Gln Glu Tyr Leu Glu Ala Gln
                 335                 340                 345

 Arg Gln Lys Leu His His Lys Ser Glu Met Gly Thr Pro Gln Gly
                 350                 355                 360

 Glu Asn Trp Leu Ser Trp Met Phe Glu Lys Leu Val Val Val Met
                 365                 370                 375

 Val Cys Tyr Phe Ile Leu Ser Ile Ile Asn Ser Met Ala Gln Ser
                 380                 385                 390

 Tyr Ala Lys Arg Ile Gln Gln Arg Leu Asn Ser Glu Glu Lys Thr
                 395                 400                 405

 Lys


<210> 6301
<211> 1271
<212> DNA
<213> Mus musculus

<400> 6301
 gatcgcaggc gagattacga ggcgaggctc gcgcgcccgc ccccgccctg 50

 gcccccagtg cccacccggt ccgcccggca cagccatgat caaggcgatc 100

 ctaatcttca acaaccacgg gaagccgcgg ctctccaagt tctaccagcc 150

 ctacagtgaa gatacacaac agcaaatcat cagggagact ttccatttgg 200

 tatctaagag agatgaaaat gtttgtaatt tcctagaagg aggattatta 250

 attggaggat ctgacaacaa actgatttat agacattatg caacgttata 300

 ttttgtcttc tgtgtggatt cttcagaaag tgaacttggc attttagatc 350

 taattcaagt atttgtggaa acattagaca aatgttttga aaatgtctgt 400

 gagctggatt tgattttcca tgtagacaag gttcacaata ttcttgcaga 450

 aatggtgatg gggggaatgg tattggagac aaatatgaat gagattgtta 500

 cacaaattga tgcacaaaat aagctggaaa aatctgaggc tggcttagca 550

 ggagctccag cccgtgctgt atcagctgta aagaatatga atcttcctga 600

 gatcccaaga aatattaaca ttggtgacat cagtataaaa gtgccaaacc 650

 tgccctcttt taaataaaaa tgtaaaaagg ccactcccag gtaaaatcca 700

 gggggaagag tcatctaagt ttaccatgca gttgtttacc aaaaatagag 750

 gaggagagtc ttaacttttg ctcttggatt taagtcaagg tactgtatag 800

 aagttgtgta aaatcagtat gaaagttcaa tgttgctgtt cttgctcagt 850

 gattttaaag aaattgagta gttcctatgt gatttttttt tttcttttct 900

 aaactgcatt cctgtgccca cctacggcat gcctctatgt attggctact 950

 acagtgtttt aaaaagtgtt tcagatattt ctctaattat gtacaaccta 1000

 aaatgttggt gttttgtatg gatcacaagt gcagcattcc ttaattcctt 1050

 ctgctatatg tcacacagtt gttatttgga gaaccaagta tgtattgcat 1100

 gaaaacatta tgactttttt ctcttagttt aaataaactc caaggtaact 1150

 ggacttctaa agcacctttc tgtttgcctg atatctactt tagcaataat 1200

 tttttttaca accctctgac tcaacaaagt aaataaaagt atattttatc 1250

 actaaaaaaa aaaaaaaaaa a 1271

<210> 6302
<211> 193
<212> PRT
<213> Mus musculus

<400> 6302
 Met Ile Lys Ala Ile Leu Ile Phe Asn Asn His Gly Lys Pro Arg
   1               5                  10                  15

 Leu Ser Lys Phe Tyr Gln Pro Tyr Ser Glu Asp Thr Gln Gln Gln
                  20                  25                  30

 Ile Ile Arg Glu Thr Phe His Leu Val Ser Lys Arg Asp Glu Asn
                  35                  40                  45

 Val Cys Asn Phe Leu Glu Gly Gly Leu Leu Ile Gly Gly Ser Asp
                  50                  55                  60

 Asn Lys Leu Ile Tyr Arg His Tyr Ala Thr Leu Tyr Phe Val Phe
                  65                  70                  75

 Cys Val Asp Ser Ser Glu Ser Glu Leu Gly Ile Leu Asp Leu Ile
                  80                  85                  90

 Gln Val Phe Val Glu Thr Leu Asp Lys Cys Phe Glu Asn Val Cys
                  95                 100                 105

 Glu Leu Asp Leu Ile Phe His Val Asp Lys Val His Asn Ile Leu
                 110                 115                 120

 Ala Glu Met Val Met Gly Gly Met Val Leu Glu Thr Asn Met Asn
                 125                 130                 135

 Glu Ile Val Thr Gln Ile Asp Ala Gln Asn Lys Leu Glu Lys Ser
                 140                 145                 150

 Glu Ala Gly Leu Ala Gly Ala Pro Ala Arg Ala Val Ser Ala Val
                 155                 160                 165

 Lys Asn Met Asn Leu Pro Glu Ile Pro Arg Asn Ile Asn Ile Gly
                 170                 175                 180

 Asp Ile Ser Ile Lys Val Pro Asn Leu Pro Ser Phe Lys
                 185                 190

<210> 6303
<211> 865
<212> DNA
<213> Homo sapien

<400> 6303
 ctcaaacacc gcctgctaaa aatacccgac tggaggagca taaaagcgca 50

 gccgagccca gcgccccgca cttttctgag cagacgtcca gagcagagtc 100

 agccagcatg accgagcgcc gcgtcccctt ctcgctcctg cggggcccca 150

 gctgggaccc cttccgcgac tggtacccgc atagccgcct cttcgaccag 200

 gccttcgggc tgccccggct gccggaggag tggtcgcagt ggttaggcgg 250

 cagcagctgg ccaggctacg tgcgccccct gccccccgcc gccatcgaga 300

 gccccgcagt ggccgcgccc gcctacagcc gcgcgctcag ccggcaactc 350

 agcagcgggg tctcggagat ccggcacact gcggaccgct ggcgcgtgtc 400

 cctggatgtc aaccacttcg ccccggacga gctgacggtc aagaccaagg 450

 atggcgtggt ggagatcacc ggcaagcacg aggagcggca ggacgagcat 500

 ggctacatct cccggtgctt cacgcggaaa tacacgctgc cccccggtgt 550

 ggaccccacc caagtttcct cctccctgtc ccctgagggc acactgaccg 600

 tggaggcccc catgcccaag ctagccacgc agtccaacga gatcaccatc 650

 ccagtcacct tcgagtcgcg ggcccagctt gggggcccag aagctgcaaa 700

 atccgatgag actgccgcca agtaaagcct tagcctggat gcccacccct 750

 gctgccgcca ctggctgtgc ctcccccgcc acctgtgtgt tcttttgata 800

 catttatctt ctgtttttct caaataaagt tcaaagcaac cacctgtaaa 850

 aaaaaaaaaa aaaaa 865

<210> 6304
<211> 205
<212> PRT
<213> Homo sapien

<400> 6304
 Met Thr Glu Arg Arg Val Pro Phe Ser Leu Leu Arg Gly Pro Ser
   1               5                  10                  15

 Trp Asp Pro Phe Arg Asp Trp Tyr Pro His Ser Arg Leu Phe Asp
                  20                  25                  30

 Gln Ala Phe Gly Leu Pro Arg Leu Pro Glu Glu Trp Ser Gln Trp
                  35                  40                  45

 Leu Gly Gly Ser Ser Trp Pro Gly Tyr Val Arg Pro Leu Pro Pro
                  50                  55                  60

 Ala Ala Ile Glu Ser Pro Ala Val Ala Ala Pro Ala Tyr Ser Arg
                  65                  70                  75

 Ala Leu Ser Arg Gln Leu Ser Ser Gly Val Ser Glu Ile Arg His
                  80                  85                  90

 Thr Ala Asp Arg Trp Arg Val Ser Leu Asp Val Asn His Phe Ala
                  95                 100                 105

 Pro Asp Glu Leu Thr Val Lys Thr Lys Asp Gly Val Val Glu Ile
                 110                 115                 120

 Thr Gly Lys His Glu Glu Arg Gln Asp Glu His Gly Tyr Ile Ser
                 125                 130                 135

 Arg Cys Phe Thr Arg Lys Tyr Thr Leu Pro Pro Gly Val Asp Pro
                 140                 145                 150

 Thr Gln Val Ser Ser Ser Leu Ser Pro Glu Gly Thr Leu Thr Val
                 155                 160                 165

 Glu Ala Pro Met Pro Lys Leu Ala Thr Gln Ser Asn Glu Ile Thr
                 170                 175                 180

 Ile Pro Val Thr Phe Glu Ser Arg Ala Gln Leu Gly Gly Pro Glu
                 185                 190                 195

 Ala Ala Lys Ser Asp Glu Thr Ala Ala Lys
                 200                 205

<210> 6305
<211> 1355
<212> DNA
<213> Homo sapien

<400> 6305
 cagtggctgg taggcagtgg ctgggaggca gcggcccaat tagtgtcgtg 50

 cggcccgtgg cgaggcgagg tccggggagc gagcgagcaa gcaaggcggg 100

 aggggtggcc ggagctgcgg cggctggcac aggaggagga gcccgggcgg 150

 gcgaggggcg gccggagagc gccagggcct gagctgccgg agcggcgcct 200

 gtgagtgagt gcagaaagca ggcgcccgcg cgctagccgt ggcaggagca 250

 gcccgcacgc cgcgctctct ccctgggcga cctgcagttt gcaatatgac 300

 tttggaggaa ttctcggctg gagagcagaa gaccgaaagg atggataagg 350

 tgggggatgc cctggaggaa gtgctcagca aagccctgag tcagcgcacg 400

 atcactgtcg gggtgtacga agcggccaag ctgctcaacg tcgaccccga 450

 taacgtggtg ttgtgcctgc tggcggcgga cgaggacgac gacagagatg 500

 tggctctgca gatccacttc accctgatcc aggcgttttg ctgcgagaac 550

 gacatcaaca tcctgcgcgt cagcaacccg ggccggctgg cggagctcct 600

 gctcttggag accgacgctg gccccgcggc gagcgagggc gccgagcagc 650

 ccccggacct gcactgcgtg ctggtgacga atccacattc atctcaatgg 700

 aaggatcctg ccttaagtca acttatttgt ttttgccggg aaagtcgcta 750

 catggatcaa tgggttccag tgattaatct ccctgaacgg tgatggcatc 800

 tgaatgaaaa taactgaacc aaattgcact gaagtttttg aaataccttt 850

 gtagttactc aagcagttac tccctacact gatgcaagga ttacagaaac 900

 tgatgccaag gggctgagtg agttcaacta catgttctgg gggcccggag 950

 atagatgact ttgcagatgg aaagaggtga aaatgaagaa ggaagctgtg 1000

 ttgaaacaga aaaataagtc aaaaggaaca aaaattacaa agaaccatgc 1050

 aggaaggaaa actatgtatt aatttagaat ggttgagtta cattaaaata 1100

 aaccaaatat gttaaagttt aagtgtgcag ccatagtttg ggtatttttg 1150

 gtttatatgc cctcaagtaa aagaaaagcc gaaagggtta atcatatttg 1200

 aaaaccatat tttattgtat tttgatgaga tattaaattc tcaaagtttt 1250

 attataaatt ctactaagtt attttatgac atgaaaagtt atttatgcta 1300

 taaatttttt gaaacacaat acctacaata aactggtatg aataattgca 1350

 tcatt 1355

<210> 6306
<211> 165
<212> PRT
<213> Homo sapien

<400> 6306
 Met Thr Leu Glu Glu Phe Ser Ala Gly Glu Gln Lys Thr Glu Arg
   1               5                  10                  15

 Met Asp Lys Val Gly Asp Ala Leu Glu Glu Val Leu Ser Lys Ala
                  20                  25                  30

 Leu Ser Gln Arg Thr Ile Thr Val Gly Val Tyr Glu Ala Ala Lys
                  35                  40                  45

 Leu Leu Asn Val Asp Pro Asp Asn Val Val Leu Cys Leu Leu Ala
                  50                  55                  60

 Ala Asp Glu Asp Asp Asp Arg Asp Val Ala Leu Gln Ile His Phe
                  65                  70                  75

 Thr Leu Ile Gln Ala Phe Cys Cys Glu Asn Asp Ile Asn Ile Leu
                  80                  85                  90

 Arg Val Ser Asn Pro Gly Arg Leu Ala Glu Leu Leu Leu Leu Glu
                  95                 100                 105

 Thr Asp Ala Gly Pro Ala Ala Ser Glu Gly Ala Glu Gln Pro Pro
                 110                 115                 120

 Asp Leu His Cys Val Leu Val Thr Asn Pro His Ser Ser Gln Trp
                 125                 130                 135

 Lys Asp Pro Ala Leu Ser Gln Leu Ile Cys Phe Cys Arg Glu Ser
                 140                 145                 150

 Arg Tyr Met Asp Gln Trp Val Pro Val Ile Asn Leu Pro Glu Arg
                 155                 160                 165

<210> 6307
<211> 2587
<212> DNA
<213> Homo sapien

<400> 6307
 ggcacacacg aggaggaggg ttgagctgct gccgccgccg cctctgtcgt 50

 cgtcgcgagt gtggagtcgg gactggagct gctgccgcgg cgacgccggg 100

 gatctttgtc gctagctccc ggcccttctg ccccgccgcc ttccctcagt 150

 cagcgttgcc cactcctctc cggccgggcg cccctgcctc catttctcgc 200

 tctctgtcca ccacacacac ggcccccccg atcatggatc cgggcagtgg 250

 cggcggcggc ggcggcggcg gcggcggcgg gagcagcagc ggcagcagca 300

 gcagcgactc ggcgcctgac tgctgggacc aggcggacat ggaagccccc 350

 gggccgggcc cttgcggcgg cggcggcttc cctggcggcg gcggccgagg 400

 cccagcggga gaacctcagc gcggccttca gccggcaact caacgtcaac 450

 gccaagccct tcgtgcccaa cgtccacgcc gccgagttcg tgccgtcctt 500

 cctgcggggc ccggcagcgc cgccaccccc agctggcggc gccgccaata 550

 accacggagc cggcagcggc gcgggaggcc gtgcggcacc tgtggaatcc 600

 tctcaagagg aacagtcatt gtgtgaaggt tcaaattcag ctgttagcat 650

 ggaactttca gaacctattg tagaaaatgg agagacagaa atgtctccag 700

 aagaatcatg ggagcacaaa gaagaaataa gtgaagcaga gccagggggt 750

 ggttccttgg gagatggaag gccgccagag gaaagtgccc atgaaatgat 800

 ggaggaggaa gaggaaatcc caaaacctaa gtctgtggtt gcaccgccag 850

 gtgctcctaa gaaagagcat gtaaatgtag tattcattgg gcacgtagat 900

 gctggcaagt caaccattgg aggacaaata atgtatttga ctggaatggt 950

 tgacaaaagg acgcttgaaa agtatgaaag agaagctaaa gagaaaaaca 1000

 gagaaacttg gtacttgtct tgggccttag acacaaatca ggaagaacga 1050

 gacaagggta aaacagtaga agtgggtcgt gcctattttg aaaccgaaaa 1100

 gaagcatttc acaattctag atgcccctgg ccacaagagt tttgtcccaa 1150

 atatgattgg tggtgcctct caagctgatt tggctgtgct ggtaatctca 1200

 gccaggaaag gagagtttga aactggattt gaaaaaggag gacagacaag 1250

 agaacatgca atgttggcaa agacagcagg tgtaaaacac ctaattgtgc 1300

 taattaataa gatggatgat ccaacagtaa attggagcaa tgagagatat 1350

 gaagaatgta aggagaaact agtgccattt ttgaaaaaag ttggcttcaa 1400

 tcccaaaaag gacattcact ttatgccctg ctcaggactt actggagcaa 1450

 atctcaaaga gcagtcggat ttctgtcctt ggtacattgg attaccgttt 1500

 attccatatc tggataattt gccgaacttc aatagatcag ttgatggacc 1550

 aatcaggctg ccaattgtgg ataagtacaa ggatatgggc actgtggtcc 1600

 tgggaaagct ggaatcagga tctatttgta aaggccagca gcttgtgatg 1650

 atgccaaaca agcacaacgt ggaagttctt ggaatacttt ccgatgatgt 1700

 agagactgat accgtagccc caggtgaaaa cctcaaaatc agactgaaag 1750

 gaattgaaga agaggagatt cttccagggt ttatactttg tgatcctaat 1800

 aatctttgtc attctggacg cacatttgat gcccagatag tgattataga 1850

 gcacaaatcc atcatctgcc caggctataa tgcggtgctg catattcata 1900

 cctgtattga ggaggtggaa ataacagcct taatctgctt ggtagacaaa 1950

 aaatcaggag aaaaaagtaa gacccgaccc cgttttgtga aacaagatca 2000

 agtatgcatt gctcgcttaa ggacagcagg aaccatctgc cttgagacct 2050

 ttaaagactt ccctcagatg ggtcgtttca ccttaagaga tgagggtaag 2100

 accattgcaa ttggaaaagt tctgaaactg gttccagaga aagactaagc 2150

 attttcttga tgaccctgca caatactgtg aggaaaattg actgcagaag 2200

 cctacttcac accgccttct cttattttct gcccattgat aaacctctcc 2250

 ccatattttg caaagaggaa attcacagca aaagtccaca ttatgtcagc 2300

 tttctcatat tgagagctct gctatgccac tgttgaattt ttcccaagat 2350

 tcctgtccct agccctcact tcaaactctg cttccttgga cagatttggc 2400

 aatagctttg taagtgatgt ggacataatt gcctacaata atgaaaacct 2450

 acaggaattt ttttattttt cattttcccc ttaggcatat ttagtatttt 2500

 tcccccaggc cagatcattc gtgagtgtgc gagtgtgtgt gcacatgtta 2550

 caaaggcaac taccatgtta ataaaatatt caatttg 2587

<210> 6308
<211> 499
<212> PRT
<213> Homo sapien

<400> 6308
 Met Glu Leu Ser Glu Pro Ile Val Glu Asn Gly Glu Thr Glu Met
   1               5                  10                  15

 Ser Pro Glu Glu Ser Trp Glu His Lys Glu Glu Ile Ser Glu Ala
                  20                  25                  30

 Glu Pro Gly Gly Gly Ser Leu Gly Asp Gly Arg Pro Pro Glu Glu
                  35                  40                  45

 Ser Ala His Glu Met Met Glu Glu Glu Glu Glu Ile Pro Lys Pro
                  50                  55                  60

 Lys Ser Val Val Ala Pro Pro Gly Ala Pro Lys Lys Glu His Val
                  65                  70                  75

 Asn Val Val Phe Ile Gly His Val Asp Ala Gly Lys Ser Thr Ile
                  80                  85                  90

 Gly Gly Gln Ile Met Tyr Leu Thr Gly Met Val Asp Lys Arg Thr
                  95                 100                 105

 Leu Glu Lys Tyr Glu Arg Glu Ala Lys Glu Lys Asn Arg Glu Thr
                 110                 115                 120

 Trp Tyr Leu Ser Trp Ala Leu Asp Thr Asn Gln Glu Glu Arg Asp
                 125                 130                 135

 Lys Gly Lys Thr Val Glu Val Gly Arg Ala Tyr Phe Glu Thr Glu
                 140                 145                 150

 Lys Lys His Phe Thr Ile Leu Asp Ala Pro Gly His Lys Ser Phe
                 155                 160                 165

 Val Pro Asn Met Ile Gly Gly Ala Ser Gln Ala Asp Leu Ala Val
                 170                 175                 180

 Leu Val Ile Ser Ala Arg Lys Gly Glu Phe Glu Thr Gly Phe Glu
                 185                 190                 195

 Lys Gly Gly Gln Thr Arg Glu His Ala Met Leu Ala Lys Thr Ala
                 200                 205                 210

 Gly Val Lys His Leu Ile Val Leu Ile Asn Lys Met Asp Asp Pro
                 215                 220                 225

 Thr Val Asn Trp Ser Asn Glu Arg Tyr Glu Glu Cys Lys Glu Lys
                 230                 235                 240

 Leu Val Pro Phe Leu Lys Lys Val Gly Phe Asn Pro Lys Lys Asp
                 245                 250                 255

 Ile His Phe Met Pro Cys Ser Gly Leu Thr Gly Ala Asn Leu Lys
                 260                 265                 270

 Glu Gln Ser Asp Phe Cys Pro Trp Tyr Ile Gly Leu Pro Phe Ile
                 275                 280                 285

 Pro Tyr Leu Asp Asn Leu Pro Asn Phe Asn Arg Ser Val Asp Gly
                 290                 295                 300

 Pro Ile Arg Leu Pro Ile Val Asp Lys Tyr Lys Asp Met Gly Thr
                 305                 310                 315

 Val Val Leu Gly Lys Leu Glu Ser Gly Ser Ile Cys Lys Gly Gln
                 320                 325                 330

 Gln Leu Val Met Met Pro Asn Lys His Asn Val Glu Val Leu Gly
                 335                 340                 345

 Ile Leu Ser Asp Asp Val Glu Thr Asp Thr Val Ala Pro Gly Glu
                 350                 355                 360

 Asn Leu Lys Ile Arg Leu Lys Gly Ile Glu Glu Glu Glu Ile Leu
                 365                 370                 375

 Pro Gly Phe Ile Leu Cys Asp Pro Asn Asn Leu Cys His Ser Gly
                 380                 385                 390

 Arg Thr Phe Asp Ala Gln Ile Val Ile Ile Glu His Lys Ser Ile
                 395                 400                 405

 Ile Cys Pro Gly Tyr Asn Ala Val Leu His Ile His Thr Cys Ile
                 410                 415                 420

 Glu Glu Val Glu Ile Thr Ala Leu Ile Cys Leu Val Asp Lys Lys
                 425                 430                 435

 Ser Gly Glu Lys Ser Lys Thr Arg Pro Arg Phe Val Lys Gln Asp
                 440                 445                 450

 Gln Val Cys Ile Ala Arg Leu Arg Thr Ala Gly Thr Ile Cys Leu
                 455                 460                 465

 Glu Thr Phe Lys Asp Phe Pro Gln Met Gly Arg Phe Thr Leu Arg
                 470                 475                 480

 Asp Glu Gly Lys Thr Ile Ala Ile Gly Lys Val Leu Lys Leu Val
                 485                 490                 495

 Pro Glu Lys Asp


<210> 6309
<211> 1746
<212> DNA
<213> Homo sapien

<400> 6309
 gagcctgact tcagcgctcc cactctcggc cgacacccct catggccaac 50

 cgttacacca tggatctgac tgccatctac gagagcctcc tgtcgctgag 100

 ccctgacgtg cccgtgccat ccgaccatgg agggactgag tccagcccag 150

 gctggggctc ctcgggaccc tggagcctga gcccctccga ctccagcccg 200

 tctggggtca cctcccgcct gcctggccgc tccaccagcc tagtggaggg 250

 ccgcagctgt ggctgggtgc ccccaccccc tggcttcgca ccgctggctc 300

 cccgcctggg ccctgagctg tcaccctcac ccacttcgcc cactgcaacc 350

 tccaccaccc cctcgcgcta caagactgag ctatgtcgga ccttctcaga 400

 gagtgggcgc tgccgctacg gggccaagtg ccagtttgcc catggcctgg 450

 gcgagctgcg ccaggccaat cgccacccca aatacaagac ggaactctgt 500

 cacaagttct acctccaggg ccgctgcccc tacggctctc gctgccactt 550

 catccacaac cctagcgaag acctggcggc cccgggccac cctcctgtgc 600

 ttcgccagag catcagcttc tccggcctgc cctctggccg ccggacctca 650

 ccaccaccac caggcctggc cggcccttcc ctgtcctcca gctccttctc 700

 gccctccagc tccccaccac cacctgggga ccttccactg tcaccctctg 750

 ccttctctgc tgcccctggc acccccctgg ctcgaagaga ccccacccca 800

 gtctgttgcc cctcctgccg aagggccact cctatcagcg tctgggggcc 850

 cttgggtggc ctggttcgga ccccctctgt acagtccctg ggatccgacc 900

 ctgatgaata tgccagcagc ggcagcagcc tggggggctc tgactctccc 950

 gtcttcgagg cgggagtttt tgcaccaccc cagcccgtgg cagccccccg 1000

 gcgactcccc atcttcaatc gcatctctgt ttctgagtga caaagtgact 1050

 gcccggtcag atcagctgga tctcagcggg gagccacgtc tcttgcactg 1100

 tggtctctgc atggacccca gggctgtggg gacttggggg acagtaatca 1150

 agtaatcccc ttttccagaa tgcattaacc cactcccctg acctcacgct 1200

 ggggcaggtc cccaagtgtg caagctcagt attcatgatg gtgggggatg 1250

 gagtgtcttc cgaggttctt gggggaaaaa aaattgtagc atatttaagg 1300

 gaggcaatga accctctccc ccacctcttc cctgcccaaa tctgtctcct 1350

 agaatcttat gtgctgtgaa taataggcct tcactgcccc tccagttttt 1400

 atagacctga ggttccagtg tctcctggta actggaacct ctcctgaggg 1450

 ggaatcctgg tgctcaaatt accctccaaa agcaagtagc caaagccgtt 1500

 gccaaacccc acccataaat caatgggccc tttatttatg acgactttat 1550

 ttattctaat atgattttat agtatttata tatattgggt cgtctgcttc 1600

 ccttgtattt ttcttccttt ttttgtaata ttgaaaacga cgatataatt 1650

 attataagta gactataata tatttagtaa tatatattat taccttaaaa 1700

 gtctattttt gtgttttggg catttttaaa taaacaatct gagtgt 1746

<210> 6310
<211> 326
<212> PRT
<213> Homo sapien

<400> 6310
 Met Asp Leu Thr Ala Ile Tyr Glu Ser Leu Leu Ser Leu Ser Pro
   1               5                  10                  15

 Asp Val Pro Val Pro Ser Asp His Gly Gly Thr Glu Ser Ser Pro
                  20                  25                  30

 Gly Trp Gly Ser Ser Gly Pro Trp Ser Leu Ser Pro Ser Asp Ser
                  35                  40                  45

 Ser Pro Ser Gly Val Thr Ser Arg Leu Pro Gly Arg Ser Thr Ser
                  50                  55                  60

 Leu Val Glu Gly Arg Ser Cys Gly Trp Val Pro Pro Pro Pro Gly
                  65                  70                  75

 Phe Ala Pro Leu Ala Pro Arg Leu Gly Pro Glu Leu Ser Pro Ser
                  80                  85                  90

 Pro Thr Ser Pro Thr Ala Thr Ser Thr Thr Pro Ser Arg Tyr Lys
                  95                 100                 105

 Thr Glu Leu Cys Arg Thr Phe Ser Glu Ser Gly Arg Cys Arg Tyr
                 110                 115                 120

 Gly Ala Lys Cys Gln Phe Ala His Gly Leu Gly Glu Leu Arg Gln
                 125                 130                 135

 Ala Asn Arg His Pro Lys Tyr Lys Thr Glu Leu Cys His Lys Phe
                 140                 145                 150

 Tyr Leu Gln Gly Arg Cys Pro Tyr Gly Ser Arg Cys His Phe Ile
                 155                 160                 165

 His Asn Pro Ser Glu Asp Leu Ala Ala Pro Gly His Pro Pro Val
                 170                 175                 180

 Leu Arg Gln Ser Ile Ser Phe Ser Gly Leu Pro Ser Gly Arg Arg
                 185                 190                 195

 Thr Ser Pro Pro Pro Pro Gly Leu Ala Gly Pro Ser Leu Ser Ser
                 200                 205                 210

 Ser Ser Phe Ser Pro Ser Ser Ser Pro Pro Pro Pro Gly Asp Leu
                 215                 220                 225

 Pro Leu Ser Pro Ser Ala Phe Ser Ala Ala Pro Gly Thr Pro Leu
                 230                 235                 240

 Ala Arg Arg Asp Pro Thr Pro Val Cys Cys Pro Ser Cys Arg Arg
                 245                 250                 255

 Ala Thr Pro Ile Ser Val Trp Gly Pro Leu Gly Gly Leu Val Arg
                 260                 265                 270

 Thr Pro Ser Val Gln Ser Leu Gly Ser Asp Pro Asp Glu Tyr Ala
                 275                 280                 285

 Ser Ser Gly Ser Ser Leu Gly Gly Ser Asp Ser Pro Val Phe Glu
                 290                 295                 300

 Ala Gly Val Phe Ala Pro Pro Gln Pro Val Ala Ala Pro Arg Arg
                 305                 310                 315

 Leu Pro Ile Phe Asn Arg Ile Ser Val Ser Glu
                 320                 325

<210> 6311
<211> 1408
<212> DNA
<213> Homo sapien

<400> 6311
 cgggaacgcc gctcttcgcc tctcagcggc ggcttgtcct ttgttccgga 50

 cgcccgctcc tcagccctgc gtcctggggt cgctgctgca tcccgcacgc 100

 ctccaccggc tgcagaccca tggccgagcg cggggaactc gacttgaccg 150

 gcgccaaaca gaacacagga gtgtggctag tcaaggttcc taaatatttg 200

 tcacagcaat gggctaaagc ctctggaaga ggtgaagttg ggaaactgcg 250

 gattgccaag actcaaggaa ggactgaggt gtcatttact ttgaatgagg 300

 atcttgcaaa tattcatgat attggtggaa aaccagcttc agtcagtgct 350

 cctagagaac atccatttgt cttgcaaagt gttggaggac agacattaac 400

 agtatttact gagagctcat cagataagct gtcattggaa ggaatagtgg 450

 tacaaagagc tgaatgccga ccagctgcca gtgaaaacta catgcgatta 500

 aaaagattgc aaatagaaga gtcttccaaa ccagtgaggc tatcacaaca 550

 gctggacaaa gttgtaacaa ccaattacaa acctgttgct aatcatcaat 600

 acaatatcga atatgaaagg aaaaagaaag aagacggaaa gcgagctcga 650

 gctgataaac aacatgtttt agacatgcta ttttcagcct ttgagaaaca 700

 tcaatactat aatcttaagg acttggtgga catcacaaaa caacctgtgg 750

 tgtacctgaa ggaaatctta aaagaaattg gtgttcagaa tgtaaaaggg 800

 atccacaaaa acacatggga gctgaagcca gagtacagac actatcaagg 850

 agaagaaaag agtgactaag aagactccta gccagcatgc tagtgaaagg 900

 ctagcagcga tgctatgcaa aaggcgctga tactggaagg cttgaacacc 950

 gtatgtttaa taggggttaa gtgacagtac tttgatttct ctcggtaaat 1000

 tttttaaacc tgtaaggctt gtaaagtttc ttaactgttt ttttgaggag 1050

 aaagaacaga tttatttata gacttaactt gtattaaacc agattattca 1100

 cagtaggaat aggggttgga ggattaagag ggtttttctt aaatattagc 1150

 ttttaatgtg tacaattagg aaattttttt aagtgaggac tctctaccct 1200

 tgccgtatct aaggagctga ggtaatacag atccaaggag aattgtatag 1250

 caagaaaaaa acagtcaact acagaaactc ttaaaaggaa taaaaaccca 1300

 aagttcctta ttttgaaatt gtcaaagaac aaacggtgtt tttcttttaa 1350

 acaggtgatc acgtttcttt tcatactcaa cgttaataaa aggagagagt 1400

 ttgtagtg 1408

<210> 6312
<211> 249
<212> PRT
<213> Homo sapien

<400> 6312
 Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn
   1               5                  10                  15

 Thr Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln
                  20                  25                  30

 Trp Ala Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile
                  35                  40                  45

 Ala Lys Thr Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu
                  50                  55                  60

 Asp Leu Ala Asn Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val
                  65                  70                  75

 Ser Ala Pro Arg Glu His Pro Phe Val Leu Gln Ser Val Gly Gly
                  80                  85                  90

 Gln Thr Leu Thr Val Phe Thr Glu Ser Ser Ser Asp Lys Leu Ser
                  95                 100                 105

 Leu Glu Gly Ile Val Val Gln Arg Ala Glu Cys Arg Pro Ala Ala
                 110                 115                 120

 Ser Glu Asn Tyr Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser
                 125                 130                 135

 Ser Lys Pro Val Arg Leu Ser Gln Gln Leu Asp Lys Val Val Thr
                 140                 145                 150

 Thr Asn Tyr Lys Pro Val Ala Asn His Gln Tyr Asn Ile Glu Tyr
                 155                 160                 165

 Glu Arg Lys Lys Lys Glu Asp Gly Lys Arg Ala Arg Ala Asp Lys
                 170                 175                 180

 Gln His Val Leu Asp Met Leu Phe Ser Ala Phe Glu Lys His Gln
                 185                 190                 195

 Tyr Tyr Asn Leu Lys Asp Leu Val Asp Ile Thr Lys Gln Pro Val
                 200                 205                 210

 Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile Gly Val Gln Asn Val
                 215                 220                 225

 Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys Pro Glu Tyr Arg
                 230                 235                 240

 His Tyr Gln Gly Glu Glu Lys Ser Asp
                 245

<210> 6313
<211> 1559
<212> DNA
<213> Homo sapien

<400> 6313
 gtttgagcag cattgttaga gcctgtggaa aacactttac aactgtgtaa 50

 ctgtcttcat ctttacagag gaatagtcta caaggaagac ttgtaacctg 100

 gagaagagac ctgtcattta ctacatcctt tatagtgatg ctacaggacg 150

 aagaggaatg gataaaaaca ttggcgagca actcaataaa gcgtatgaag 200

 ccttccggca ggcatgcatg gatagagatt ctgcagtaaa agaattacag 250

 caaaagactg agaactatga gcagagaata cgtgaacaac aggaacagct 300

 gtcacttcaa cagactatta ttgacaagct aaaatctcag ttacttcttg 350

 tgaattccac tcaagataac aattatggct gtgttcctct gcttgaagac 400

 agtgaaacaa gaaagaataa tttgactctt gatcagccac aagataaagt 450

 gatttcagga atagcaagag aaaaactacc aaaggtaaga agacaagagg 500

 tttcttctcc tagaaaagaa acttcagcaa ggagtcttgg cagtcctttg 550

 ctccatgaaa ggggtaatat agagaagact ttctgggatc tgaaagaaga 600

 atttcataaa atatgcatgc tagcaaaagc acagaaagac cacttaagca 650

 aacttaatat accagacact gcaactgaaa cacagtgctc tgtgcctata 700

 cagtgtacgg ataaaacaga taaacaagaa gcgctgttta agcctcaggc 750

 taaagatgat ataaatagag gtgcaccatc catcacatct gtcacaccaa 800

 gaggactgtg cagagatgag gaagacacct cttttgaatc actttctaaa 850

 ttcaatgtca agtttccacc tatggacaat gactcaactt tcttacatag 900

 cactccagag agacccggca tccttagtcc tgccacgtct gaggcagtgt 950

 gccaagagaa atttaatatg gagttcagag acaacccagg gaactttgtt 1000

 aaaacagaag aaactttatt tgaaattcag ggaattgacc ccatagcttc 1050

 agctatacaa aaccctaaaa caactgacaa aacaaagccc tcaaatctcg 1100

 taaacacttg tatcaggaca actctggata gagctgcgtg tttgccacct 1150

 ggagaccata atgcattata tgtaaatagc ttcccacttc tggacccatc 1200

 tgatgcacct tttccctcac tcgattcccc gggaaaagca atccgaggac 1250

 cacagcagcc catttggaag ccctttccta atcaagacag tgactcggtg 1300

 gtactaagtg gcacagactc agaactgcat atacctcgag tatgtgaatt 1350

 ctgtcaagca gttttcccac catccattac atccaggggg gatttccttc 1400

 ggcatcttaa ttcacacttc aatggagaga cttaagacac atttgaaaac 1450

 agacatatca agttctatgt gatgattttg ggtttttaat actataaata 1500

 cttgattgta aactaaattc aagatcattt attggaaaat ctagtttcac 1550

 agctatttg 1559

<210> 6314
<211> 425
<212> PRT
<213> Homo sapien

<400> 6314
 Met Asp Lys Asn Ile Gly Glu Gln Leu Asn Lys Ala Tyr Glu Ala
   1               5                  10                  15

 Phe Arg Gln Ala Cys Met Asp Arg Asp Ser Ala Val Lys Glu Leu
                  20                  25                  30

 Gln Gln Lys Thr Glu Asn Tyr Glu Gln Arg Ile Arg Glu Gln Gln
                  35                  40                  45

 Glu Gln Leu Ser Leu Gln Gln Thr Ile Ile Asp Lys Leu Lys Ser
                  50                  55                  60

 Gln Leu Leu Leu Val Asn Ser Thr Gln Asp Asn Asn Tyr Gly Cys
                  65                  70                  75

 Val Pro Leu Leu Glu Asp Ser Glu Thr Arg Lys Asn Asn Leu Thr
                  80                  85                  90

 Leu Asp Gln Pro Gln Asp Lys Val Ile Ser Gly Ile Ala Arg Glu
                  95                 100                 105

 Lys Leu Pro Lys Val Arg Arg Gln Glu Val Ser Ser Pro Arg Lys
                 110                 115                 120

 Glu Thr Ser Ala Arg Ser Leu Gly Ser Pro Leu Leu His Glu Arg
                 125                 130                 135

 Gly Asn Ile Glu Lys Thr Phe Trp Asp Leu Lys Glu Glu Phe His
                 140                 145                 150

 Lys Ile Cys Met Leu Ala Lys Ala Gln Lys Asp His Leu Ser Lys
                 155                 160                 165

 Leu Asn Ile Pro Asp Thr Ala Thr Glu Thr Gln Cys Ser Val Pro
                 170                 175                 180

 Ile Gln Cys Thr Asp Lys Thr Asp Lys Gln Glu Ala Leu Phe Lys
                 185                 190                 195

 Pro Gln Ala Lys Asp Asp Ile Asn Arg Gly Ala Pro Ser Ile Thr
                 200                 205                 210

 Ser Val Thr Pro Arg Gly Leu Cys Arg Asp Glu Glu Asp Thr Ser
                 215                 220                 225

 Phe Glu Ser Leu Ser Lys Phe Asn Val Lys Phe Pro Pro Met Asp
                 230                 235                 240

 Asn Asp Ser Thr Phe Leu His Ser Thr Pro Glu Arg Pro Gly Ile
                 245                 250                 255

 Leu Ser Pro Ala Thr Ser Glu Ala Val Cys Gln Glu Lys Phe Asn
                 260                 265                 270

 Met Glu Phe Arg Asp Asn Pro Gly Asn Phe Val Lys Thr Glu Glu
                 275                 280                 285

 Thr Leu Phe Glu Ile Gln Gly Ile Asp Pro Ile Ala Ser Ala Ile
                 290                 295                 300

 Gln Asn Pro Lys Thr Thr Asp Lys Thr Lys Pro Ser Asn Leu Val
                 305                 310                 315

 Asn Thr Cys Ile Arg Thr Thr Leu Asp Arg Ala Ala Cys Leu Pro
                 320                 325                 330

 Pro Gly Asp His Asn Ala Leu Tyr Val Asn Ser Phe Pro Leu Leu
                 335                 340                 345

 Asp Pro Ser Asp Ala Pro Phe Pro Ser Leu Asp Ser Pro Gly Lys
                 350                 355                 360

 Ala Ile Arg Gly Pro Gln Gln Pro Ile Trp Lys Pro Phe Pro Asn
                 365                 370                 375

 Gln Asp Ser Asp Ser Val Val Leu Ser Gly Thr Asp Ser Glu Leu
                 380                 385                 390

 His Ile Pro Arg Val Cys Glu Phe Cys Gln Ala Val Phe Pro Pro
                 395                 400                 405

 Ser Ile Thr Ser Arg Gly Asp Phe Leu Arg His Leu Asn Ser His
                 410                 415                 420

 Phe Asn Gly Glu Thr
                 425

<210> 6315
<211> 1697
<212> DNA
<213> Homo sapien

<400> 6315
 ggatcgaggg gactctgacc acagcctgtg gctgggaagg gagacagagg 50

 cggcggcggc tcaggggaaa cgaggctgca gtggtggtag taggaagatg 100

 tcgggcgagg acgagcaaca ggagcaaact atcgctgagg acctggtcgt 150

 gaccaagtat aagatggggg gcgacatcgc caacagggta cttcggtcct 200

 tggtggaagc atctagctca ggtgtgtcgg tactcagcct gtgtgagaaa 250

 ggtgatgcca tgattatgga agaaacaggg aaaatcttca agaaagaaaa 300

 ggaaatgaag aaaggtattg cttttcccac cagcatttcg gtaaataact 350

 gtgtatgtca cttctcccct ttgaagagcg accaggatta tattctcaag 400

 gaaggtgact tggtaaaaat tgaccttggg gtccatgtgg atggcttcat 450

 cgctaatgta gctcacactt ttgtggttga tgtagctcag gggacccaag 500

 taacagggag gaaagcagat gttattaagg cagctcacct ttgtgctgaa 550

 gctgccctac gcctggtcaa acctggaaat cagaacacac aagtgacaga 600

 agcctggaac aaagttgccc actcatttaa ctgcacgcca atagaaggta 650

 tgctgtcaca ccagttgaag cagcatgtca tcgatggaga aaaaaccatt 700

 atccagaatc ccacagacca gcagaagaag gaccatgaaa aagctgaatt 750

 tgaggtacat gaagtatatg ctgtggatgt tctcgtcagc tcaggagagg 800

 gcaaggccaa ggatgcagga cagagaacca ctatttacaa acgagacccc 850

 tctaaacagt atggactgaa aatgaaaact tcacgtgcct tcttcagtga 900

 ggtggaaagg cgttttgatg ccatgccgtt tactttaaga gcatttgaag 950

 atgagaagaa ggctcggatg ggtgtggtgg agtgcgccaa acatgaactg 1000

 ctgcaaccat ttaatgttct ctatgagaag gagggtgaat ttgttgccca 1050

 gtttaaattt acagttctgc tcatgcccaa tggccccatg cggataacca 1100

 gtggtccctt cgagcctgac ctctacaagt ctgagatgga ggtccaggat 1150

 gcagagctaa aggccctcct ccagagttct gcaagtcgaa aaacccagaa 1200

 aaagaaaaaa aagaaggcct ccaagactgc agagaatccc accagtgggg 1250

 aaacattaga agaaaatgaa gctggggact gaggtgcgtc ccatctcccc 1300

 agcttgctgc tcctgcctca tccccttccc accaaacccc agactctgtg 1350

 aagtgcagtt cttctccacc taggaccgcc agcagagcgg ggggatctcc 1400

 ctgcccccac cccagttccc caacccactc ccttccaaca acaaccagct 1450

 ccaactgact ctggtcttgg gaggtgaggc ttcccaacca cggaagacta 1500

 ctttaaacga aaaaaagaaa ttgaataata aaatcaggag tcaaaattca 1550

 tcgtcttcaa ggcccctctt tctagccttt tctactactc tctgcttggt 1600

 caaggtttgt gccccactac agaacagggc taaattagcc accaccactg 1650

 aaaactcagc cgaatttttt tataccactc tgacgtcagc atttttt 1697

<210> 6316
<211> 394
<212> PRT
<213> Homo sapien

<400> 6316
 Met Ser Gly Glu Asp Glu Gln Gln Glu Gln Thr Ile Ala Glu Asp
   1               5                  10                  15

 Leu Val Val Thr Lys Tyr Lys Met Gly Gly Asp Ile Ala Asn Arg
                  20                  25                  30

 Val Leu Arg Ser Leu Val Glu Ala Ser Ser Ser Gly Val Ser Val
                  35                  40                  45

 Leu Ser Leu Cys Glu Lys Gly Asp Ala Met Ile Met Glu Glu Thr
                  50                  55                  60

 Gly Lys Ile Phe Lys Lys Glu Lys Glu Met Lys Lys Gly Ile Ala
                  65                  70                  75

 Phe Pro Thr Ser Ile Ser Val Asn Asn Cys Val Cys His Phe Ser
                  80                  85                  90

 Pro Leu Lys Ser Asp Gln Asp Tyr Ile Leu Lys Glu Gly Asp Leu
                  95                 100                 105

 Val Lys Ile Asp Leu Gly Val His Val Asp Gly Phe Ile Ala Asn
                 110                 115                 120

 Val Ala His Thr Phe Val Val Asp Val Ala Gln Gly Thr Gln Val
                 125                 130                 135

 Thr Gly Arg Lys Ala Asp Val Ile Lys Ala Ala His Leu Cys Ala
                 140                 145                 150

 Glu Ala Ala Leu Arg Leu Val Lys Pro Gly Asn Gln Asn Thr Gln
                 155                 160                 165

 Val Thr Glu Ala Trp Asn Lys Val Ala His Ser Phe Asn Cys Thr
                 170                 175                 180

 Pro Ile Glu Gly Met Leu Ser His Gln Leu Lys Gln His Val Ile
                 185                 190                 195

 Asp Gly Glu Lys Thr Ile Ile Gln Asn Pro Thr Asp Gln Gln Lys
                 200                 205                 210

 Lys Asp His Glu Lys Ala Glu Phe Glu Val His Glu Val Tyr Ala
                 215                 220                 225

 Val Asp Val Leu Val Ser Ser Gly Glu Gly Lys Ala Lys Asp Ala
                 230                 235                 240

 Gly Gln Arg Thr Thr Ile Tyr Lys Arg Asp Pro Ser Lys Gln Tyr
                 245                 250                 255

 Gly Leu Lys Met Lys Thr Ser Arg Ala Phe Phe Ser Glu Val Glu
                 260                 265                 270

 Arg Arg Phe Asp Ala Met Pro Phe Thr Leu Arg Ala Phe Glu Asp
                 275                 280                 285

 Glu Lys Lys Ala Arg Met Gly Val Val Glu Cys Ala Lys His Glu
                 290                 295                 300

 Leu Leu Gln Pro Phe Asn Val Leu Tyr Glu Lys Glu Gly Glu Phe
                 305                 310                 315

 Val Ala Gln Phe Lys Phe Thr Val Leu Leu Met Pro Asn Gly Pro
                 320                 325                 330

 Met Arg Ile Thr Ser Gly Pro Phe Glu Pro Asp Leu Tyr Lys Ser
                 335                 340                 345

 Glu Met Glu Val Gln Asp Ala Glu Leu Lys Ala Leu Leu Gln Ser
                 350                 355                 360

 Ser Ala Ser Arg Lys Thr Gln Lys Lys Lys Lys Lys Lys Ala Ser
                 365                 370                 375

 Lys Thr Ala Glu Asn Pro Thr Ser Gly Glu Thr Leu Glu Glu Asn
                 380                 385                 390

 Glu Ala Gly Asp


<210> 6317
<211> 1375
<212> DNA
<213> Homo sapien

<400> 6317
 aaaagcaagc caggaggtgc ttgcggccgc ttctagtagt ttccaggcgc 50

 tgccgggcgg ctggcactaa gcggtcctga ggctgtggct acggctgctc 100

 cggagctggt ggcgccgcga taggagagcc gatggccaag tggggtgagg 150

 gagacccacg ctggatcgtg gaggagcggg cggacgccac caacgtcaac 200

 aactggcact ggacggagag agatgcttca aattggtcca cggataagct 250

 gaaaacactg ttcttggcag tgcaggttca aaatgaagaa ggcaagtgtg 300

 aggtgacgga agtgagtaag cttgatggag aggcatccat taacaatcgc 350

 aaagggaaac ttatcttctt ttatgaatgg agcgtcaaac taaactggac 400

 aggtacttct aagtcaggag tacagtacaa aggacatgtg gagatcccca 450

 atttgtctga tgaaaacagc gtggatgaag tggagattag tgtgagcctt 500

 gccaaagatg agcctgacac aaatctcgtg gccttaatga aggaagaagg 550

 ggtgaaactt ctaagagaag caatgggaat ttacatcagc accctcaaaa 600

 cagagttcac ccagggcatg atcttaccta caatgaatgg agagtcagta 650

 gacccagtgg ggcagccagc actgaaaact gaggagcgca aggctaagcc 700

 tgctccttca aaaacccagg ccagacctgt tggagtcaaa atccccactt 750

 gtaagatcac tcttaaggaa accttcctga cgtcaccaga ggagctctat 800

 agagtgttta ccacccaaga gctggtgcag gcctttaccc atgctcctgc 850

 aacattagaa gcagacagag gtggaaagtt ccacatggta gatggcaacg 900

 tctctgggga atttactgat ctggtccctg agaaacatat tgtgatgaag 950

 tggaggttta aatcttggcc agagggacac tttgccacca tcaccttgac 1000

 cttcatcgac aagaacggag agactgagct gtgcatggaa ggtcgaggca 1050

 tccctgctcc tgaggaagag cggacacgac agggctggca gcggtactac 1100

 tttgagggca ttaaacagac ctttggctat ggcgcacgct tattttaggg 1150

 ccagcggcag gggactccag cctgctggac acttcagtcc agctctctcc 1200

 tgactggggc ttgcgactca caggattgca tcgtcccagc tgctaacttg 1250

 gggccggggc ccctcccttc cacatatacc ttgggtttgt gcatgttttc 1300

 tgctgggtgg gttcagaggg caatttctct tttatgtgta catatgctaa 1350

 ataaacataa tttaaaaaac aaaaa 1375

<210> 6318
<211> 338
<212> PRT
<213> Homo sapien

<400> 6318
 Met Ala Lys Trp Gly Glu Gly Asp Pro Arg Trp Ile Val Glu Glu
   1               5                  10                  15

 Arg Ala Asp Ala Thr Asn Val Asn Asn Trp His Trp Thr Glu Arg
                  20                  25                  30

 Asp Ala Ser Asn Trp Ser Thr Asp Lys Leu Lys Thr Leu Phe Leu
                  35                  40                  45

 Ala Val Gln Val Gln Asn Glu Glu Gly Lys Cys Glu Val Thr Glu
                  50                  55                  60

 Val Ser Lys Leu Asp Gly Glu Ala Ser Ile Asn Asn Arg Lys Gly
                  65                  70                  75

 Lys Leu Ile Phe Phe Tyr Glu Trp Ser Val Lys Leu Asn Trp Thr
                  80                  85                  90

 Gly Thr Ser Lys Ser Gly Val Gln Tyr Lys Gly His Val Glu Ile
                  95                 100                 105

 Pro Asn Leu Ser Asp Glu Asn Ser Val Asp Glu Val Glu Ile Ser
                 110                 115                 120

 Val Ser Leu Ala Lys Asp Glu Pro Asp Thr Asn Leu Val Ala Leu
                 125                 130                 135

 Met Lys Glu Glu Gly Val Lys Leu Leu Arg Glu Ala Met Gly Ile
                 140                 145                 150

 Tyr Ile Ser Thr Leu Lys Thr Glu Phe Thr Gln Gly Met Ile Leu
                 155                 160                 165

 Pro Thr Met Asn Gly Glu Ser Val Asp Pro Val Gly Gln Pro Ala
                 170                 175                 180

 Leu Lys Thr Glu Glu Arg Lys Ala Lys Pro Ala Pro Ser Lys Thr
                 185                 190                 195

 Gln Ala Arg Pro Val Gly Val Lys Ile Pro Thr Cys Lys Ile Thr
                 200                 205                 210

 Leu Lys Glu Thr Phe Leu Thr Ser Pro Glu Glu Leu Tyr Arg Val
                 215                 220                 225

 Phe Thr Thr Gln Glu Leu Val Gln Ala Phe Thr His Ala Pro Ala
                 230                 235                 240

 Thr Leu Glu Ala Asp Arg Gly Gly Lys Phe His Met Val Asp Gly
                 245                 250                 255

 Asn Val Ser Gly Glu Phe Thr Asp Leu Val Pro Glu Lys His Ile
                 260                 265                 270

 Val Met Lys Trp Arg Phe Lys Ser Trp Pro Glu Gly His Phe Ala
                 275                 280                 285

 Thr Ile Thr Leu Thr Phe Ile Asp Lys Asn Gly Glu Thr Glu Leu
                 290                 295                 300

 Cys Met Glu Gly Arg Gly Ile Pro Ala Pro Glu Glu Glu Arg Thr
                 305                 310                 315

 Arg Gln Gly Trp Gln Arg Tyr Tyr Phe Glu Gly Ile Lys Gln Thr
                 320                 325                 330

 Phe Gly Tyr Gly Ala Arg Leu Phe
                 335

<210> 6319
<211> 1550
<212> DNA
<213> Homo sapien

<400> 6319
 tgccgccgtc ccgcccgcca gcgccccagc gaggaagcag cgcgcagccc 50

 gcggcccagc gcacccgcag cagcgcccgc agctcgtccg cgccatgttc 100

 caggcggccg agcgccccca ggagtgggcc atggagggcc cccgcgacgg 150

 gctgaagaag gagcggctac tggacgaccg ccacgacagc ggcctggact 200

 ccatgaaaga cgaggagtac gagcagatgg tcaaggagct gcaggagatc 250

 cgcctcgagc cgcaggaggt gccgcgcggc tcggagccct ggaagcagca 300

 gctcaccgag gacggggact cgttcctgca cttggccatc atccatgaag 350

 aaaaggcact gaccatggaa gtgatccgcc aggtgaaggg agacctggct 400

 ttcctcaact tccagaacaa cctgcagcag actccactcc acttggctgt 450

 gatcaccaac cagccagaaa ttgctgaggc acttctggga gctggctgtg 500

 atcctgagct ccgagacttt cgaggaaata cccccctaca ccttgcctgt 550

 gagcagggct gcctggccag cgtgggagtc ctgactcagt cctgcaccac 600

 cccgcacctc cactccatcc tgaaggctac caactacaat ggccacacgt 650

 gtctacactt agcctctatc catggctacc tgggcatcgt ggagcttttg 700

 gtgtccttgg gtgctgatgt caatgctcag gagccctgta atggccggac 750

 tgcccttcac ctcgcagtgg acctgcaaaa tcctgacctg gtgtcactcc 800

 tgttgaagtg tggggctgat gtcaacagag ttacctacca gggctattct 850

 ccctaccagc tcacctgggg ccgcccaagc acccggatac agcagcagct 900

 gggccagctg acactagaaa accttcagat gctgccagag agtgaggatg 950

 aggagagcta tgacacagag tcagagttca cggagttcac agaggacgag 1000

 ctgccctatg atgactgtgt gtttggaggc cagcgtctga cgttatgagt 1050

 gcaaaggggc tgaaagaaca tggacttgta tatttgtaca aaaaaaaagt 1100

 tttatttttc taaaaaaaga aaaaagaaga aaaaatttaa agggtgtact 1150

 tatatccaca ctgcacactg cctagcccaa aacgtcttat tgtggtagga 1200

 tcagccctca ttttgttgct tttgtgaact ttttgtaggg gacgagaaag 1250

 atcattgaaa ttctgagaaa acttctttta aacctcacct ttgtggggtt 1300

 tttggagaag gttatcaaaa atttcatgga aggaccacat tttatattta 1350

 ttgtgcttcg agtgactgac cccagtggta tcctgtgaca tgtaacagcc 1400

 aggagtgtta agcgttcagt gatgtggggt gaaaagttac tacctgtcaa 1450

 ggtttgtgtt accctcctgt aaatggtgta cataatgtat tgttggtaat 1500

 tattttggta cttttatgat gtatatttat taaagagatt tttacaaatg 1550

<210> 6320
<211> 317
<212> PRT
<213> Homo sapien

<400> 6320
 Met Phe Gln Ala Ala Glu Arg Pro Gln Glu Trp Ala Met Glu Gly
   1               5                  10                  15

 Pro Arg Asp Gly Leu Lys Lys Glu Arg Leu Leu Asp Asp Arg His
                  20                  25                  30

 Asp Ser Gly Leu Asp Ser Met Lys Asp Glu Glu Tyr Glu Gln Met
                  35                  40                  45

 Val Lys Glu Leu Gln Glu Ile Arg Leu Glu Pro Gln Glu Val Pro
                  50                  55                  60

 Arg Gly Ser Glu Pro Trp Lys Gln Gln Leu Thr Glu Asp Gly Asp
                  65                  70                  75

 Ser Phe Leu His Leu Ala Ile Ile His Glu Glu Lys Ala Leu Thr
                  80                  85                  90

 Met Glu Val Ile Arg Gln Val Lys Gly Asp Leu Ala Phe Leu Asn
                  95                 100                 105

 Phe Gln Asn Asn Leu Gln Gln Thr Pro Leu His Leu Ala Val Ile
                 110                 115                 120

 Thr Asn Gln Pro Glu Ile Ala Glu Ala Leu Leu Gly Ala Gly Cys
                 125                 130                 135

 Asp Pro Glu Leu Arg Asp Phe Arg Gly Asn Thr Pro Leu His Leu
                 140                 145                 150

 Ala Cys Glu Gln Gly Cys Leu Ala Ser Val Gly Val Leu Thr Gln
                 155                 160                 165

 Ser Cys Thr Thr Pro His Leu His Ser Ile Leu Lys Ala Thr Asn
                 170                 175                 180

 Tyr Asn Gly His Thr Cys Leu His Leu Ala Ser Ile His Gly Tyr
                 185                 190                 195

 Leu Gly Ile Val Glu Leu Leu Val Ser Leu Gly Ala Asp Val Asn
                 200                 205                 210

 Ala Gln Glu Pro Cys Asn Gly Arg Thr Ala Leu His Leu Ala Val
                 215                 220                 225

 Asp Leu Gln Asn Pro Asp Leu Val Ser Leu Leu Leu Lys Cys Gly
                 230                 235                 240

 Ala Asp Val Asn Arg Val Thr Tyr Gln Gly Tyr Ser Pro Tyr Gln
                 245                 250                 255

 Leu Thr Trp Gly Arg Pro Ser Thr Arg Ile Gln Gln Gln Leu Gly
                 260                 265                 270

 Gln Leu Thr Leu Glu Asn Leu Gln Met Leu Pro Glu Ser Glu Asp
                 275                 280                 285

 Glu Glu Ser Tyr Asp Thr Glu Ser Glu Phe Thr Glu Phe Thr Glu
                 290                 295                 300

 Asp Glu Leu Pro Tyr Asp Asp Cys Val Phe Gly Gly Gln Arg Leu
                 305                 310                 315

 Thr Leu


<210> 6321
<211> 547
<212> DNA
<213> Homo sapien

<400> 6321
 acggaagtgt aggttacggt ctgagacatc accgccaagc tgggcatcgg 50

 ggagatggcc gagactgacc ccaagaccgt gcaggacctc acctcggtgg 100

 tgcagacact cctgcagcag atgcaagata aatttcagac catgtctgac 150

 cagatcattg ggagaattga tgatatgagt agtcgcattg atgatctgga 200

 aaagaatatc gcggacctca tgacacaggc tggggtggaa gaactggaaa 250

 gtgaaaacaa gatacctgcc acgcaaaaga gttgaaggtt gctaataatt 300

 tatactggaa tctggcattt ttccaagcca agagaagatc gaatggcttt 350

 ttgcagctaa ctactatgtg tagacaggtt ttatattata aagtatgcat 400

 tcttatcacc tagtatatag ttagtttgta gagtgatttc cccccagttt 450

 cttgaacatg gtatcttcac atcttggacc ttggtcagtt gtgctattca 500

 ttattaaaca ctaaaacttt ggcggttctt gcataaaaaa aaaaaaa 547

<210> 6322
<211> 76
<212> PRT
<213> Homo sapien

<400> 6322
 Met Ala Glu Thr Asp Pro Lys Thr Val Gln Asp Leu Thr Ser Val
   1               5                  10                  15

 Val Gln Thr Leu Leu Gln Gln Met Gln Asp Lys Phe Gln Thr Met
                  20                  25                  30

 Ser Asp Gln Ile Ile Gly Arg Ile Asp Asp Met Ser Ser Arg Ile
                  35                  40                  45

 Asp Asp Leu Glu Lys Asn Ile Ala Asp Leu Met Thr Gln Ala Gly
                  50                  55                  60

 Val Glu Glu Leu Glu Ser Glu Asn Lys Ile Pro Ala Thr Gln Lys
                  65                  70                  75

 Ser


<210> 6323
<211> 2056
<212> DNA
<213> Homo sapien

<400> 6323
 gcagccaggc gcgcactgca cagctctctt ctctcgccgc cgcccgagcg 50

 cacccttcag cccgcgcgcc ggccgtgagt cctcggtgct cgcccgccgg 100

 ccagacaaac agcccgcccg accccgtccc gaccctggcc gccccgagcg 150

 gagcctggag caaaatgatg cttcaacacc caggccaggt ctctgcctcg 200

 gaagtgagtg cttctgccat cgtcccctgc ctgtcccctc ctgggtcact 250

 ggtgtttgag gattttgcta acctgacgcc ctttgtcaag gaagagctga 300

 ggtttgccat ccagaacaag cacctctgcc accggatgtc ctctgcgctg 350

 gaatcagtca ctgtcagcga cagacccctc ggggtgtcca tcacaaaagc 400

 cgaggtagcc cctgaagaag atgaaaggaa aaagaggcga cgagaaagaa 450

 ataagattgc agctgcaaag tgccgaaaca agaagaagga gaagacggag 500

 tgcctgcagc ttcagtatta gcagagccac aggccgcctc tgtggcatca 550

 ccagggtttc tctgaagaag agggtctgca ttttcctaaa cccagtgctg 600

 ctctcccatc tcccatcttc ctctcgcagc ttgatgagcc ccggtgtgtc 650

 ccaggagtcg gagaagctgg aaagtgtgaa tgctgaactg aaggctcaga 700

 ttgaggagct caagaacgag aagcagcatt tgatatacat gctcaacctt 750

 catcggccca cgtgtattgt ccgggctcag aatgggagga ctccagaaga 800

 tgagagaaac ctctttatcc aacagataaa agaaggaaca ttgcagagct 850

 aagcagtcgt ggtatggggg cgactgggga gtcctcattg aatcctcatt 900

 ttatacccaa aaccctgaag ccattggaga gctgtcttcc tgtgtacctc 950

 tagaatccca gcagcagaga accatcaagg cgggagggcc tgcagtgatt 1000

 cagcaggccc ttcccattct gccccagagt gggtcttgga ccagggcaag 1050

 tgcatctttg cctcaactcc aggatttagg ccttaacaca ctggccattc 1100

 ttatgttcca gatggccccc agctggtgtc ctgcccgcct ttcatctgga 1150

 ttctacaaaa aaccaggatg cccaccgtta gattcaggca gcagtgtctg 1200

 tacctcgggt gggagggatg gggccatctc cttcaccgtg gctaccattg 1250

 tcactcgtag gggatgtgga gtgagaacag catttagtga agttgtgcaa 1300

 cggccagggt tgtgctttct agcaaatatg ctgttatgtc cagaaattgt 1350

 gtgtgcaaga aaactaggca atgtactctt ccgatgtttg tgtcacacaa 1400

 cactgatgtg acttttatat gctttttctc agatctggtt tctaagagtt 1450

 ttggggggcg gggctgtcac cacgtgcagt atctcaagat attcaggtgg 1500

 ccagaagagc ttgtcagcaa gaggaggaac agaattctcc cagcgttaac 1550

 acaaaatcca tgggcagcat gatggcaggt cctctgttgc aaactcagtt 1600

 ccaaagtcac aggaagaaag cagaaagttc aacttccaaa gggttaggac 1650

 tctccactca atgtcttagg tcaggagttg tgtctaggct ggaagagcca 1700

 aagaaatatt ccattttcct ttccttgtgg ttgaaaccac agtcagtgga 1750

 gagatgtttg gaacacagtc agtggagctg gtggtaccag gtttagcatt 1800

 attggatgtc aaaagcattt tttttgtcat gtagctgttt taagaaatct 1850

 ggcccagggt gtttgcagct gtgagaagtc actcacactg gccacaagga 1900

 cgctggctac tgtctattaa aattctgatg tttctgtgaa attctcagag 1950

 tgtttaattg tactcaatgg tatcattaca attttctgta agagaaaata 2000

 ttacttattt atcctagtat tcctaacctg tcagaataat aaatattgtg 2050

 gtaaaa 2056

<210> 6324
<211> 118
<212> PRT
<213> Homo sapien

<400> 6324
 Met Met Leu Gln His Pro Gly Gln Val Ser Ala Ser Glu Val Ser
   1               5                  10                  15

 Ala Ser Ala Ile Val Pro Cys Leu Ser Pro Pro Gly Ser Leu Val
                  20                  25                  30

 Phe Glu Asp Phe Ala Asn Leu Thr Pro Phe Val Lys Glu Glu Leu
                  35                  40                  45

 Arg Phe Ala Ile Gln Asn Lys His Leu Cys His Arg Met Ser Ser
                  50                  55                  60

 Ala Leu Glu Ser Val Thr Val Ser Asp Arg Pro Leu Gly Val Ser
                  65                  70                  75

 Ile Thr Lys Ala Glu Val Ala Pro Glu Glu Asp Glu Arg Lys Lys
                  80                  85                  90

 Arg Arg Arg Glu Arg Asn Lys Ile Ala Ala Ala Lys Cys Arg Asn
                  95                 100                 105

 Lys Lys Lys Glu Lys Thr Glu Cys Leu Gln Leu Gln Tyr
                 110                 115

<210> 6325
<211> 2899
<212> DNA
<213> Homo sapien

<400> 6325
 cagacggcgc tgagcgcggc ggcggcggga gcggcgtcga gtgtctccgt 50

 gcgcccgtct gtggccaagc agccagcagc ctagcagcca gtcagcttgc 100

 cgccggcggc caagcagcca accatgctca acttcggtgc ctctctccag 150

 cagactgcgg aggaaagaat ggaaatgatt tctgaaaggc caaaagagag 200

 tatgtattcc tggaacaaaa ctgcagagaa aagtgatttt gaagctgtag 250

 aagcacttat gtcaatgagc tgcagttgga agtctgattt taagaaatac 300

 gttgaaaaca gacctgttac accagtatct gatttgtcag aggaagagaa 350

 tctgcttccg ggaacacctg attttcatac aatcccagca ttttgtttga 400

 ctccacctta cagtccttct gactttgaac cctctcaagt gtcaaatctg 450

 atggcaccag cgccatctac tgtacacttc aagtcactct cagatactgc 500

 caaacctcac attgccgcac ctttcaaaga ggaagaaaag agcccagtat 550

 ctgcccccaa actccccaaa gctcaggcaa caagtgtgat tcgtcataca 600

 gctgatgccc agctatgtaa ccaccagacc tgcccaatga aagcagccag 650

 catcctcaac tatcagaaca attcttttag aagaagaacc cacctaaatg 700

 ttgaggctgc aagaaagaac ataccatgtg ccgctgtgtc accaaacaga 750

 tccaaatgtg agagaaacac agtggcagat gttgatgaga aagcaagtgc 800

 tgcactttat gacttttctg tgccttcctc agagacggtc atctgcaggt 850

 ctcagccagc ccctgtgtcc ccacaacaga agtcagtgtt ggtctctcca 900

 cctgcagtat ctgcaggggg agtgccacct atgccggtca tctgccagat 950

 ggttcccctt cctgccaaca accctgttgt gacaacagtc gttcccagca 1000

 ctcctcccag ccagccacca gccgtttgcc cccctgttgt gttcatgggc 1050

 acacaagtcc ccaaaggcgc tgtcatgttt gtggtacccc agcccgttgt 1100

 gcagagttca aagcctccgg tggtgagccc gaatggcacc agactctctc 1150

 ccattgcccc tgctcctggg ttttcccctt cagcagcaaa agtcactcct 1200

 cagattgatt catcaaggat aaggagtcac atctgtagcc acccaggatg 1250

 tggcaagaca tactttaaaa gttcccatct gaaggcccac acgaggacgc 1300

 acacaggaga aaagcctttc agctgtagct ggaaaggttg tgaaaggagg 1350

 tttgcccgtt ctgatgaact gtccagacac aggcgaaccc acacgggtga 1400

 gaagaaattt gcgtgcccca tgtgtgaccg gcggttcatg aggagtgacc 1450

 atttgaccaa gcatgcccgg cgccatctat cagccaagaa gctaccaaac 1500

 tggcagatgg aagtgagcaa gctaaatgac attgctctac ctccaacccc 1550

 tgctcccaca cagtgacaga ccggaaagtg aagagtcaga actaactttg 1600

 gtctcagcgg gagccagtgg tgatgtaaaa atgcttccac tgcaagtctg 1650

 tggccccaca acgtgggctt aaagcagaag ccccacagcc tggcacgaag 1700

 gccccgcctg ggttaggtga ctaaaagggc ttcggccaca ggcaggtcac 1750

 agaaaggcag gtttcatttc ttatcacata agagagatga gaaagctttt 1800

 attcctttga atattttttg aaggtttcag atgaggtcaa cacaggtagc 1850

 acagattttg aatctgtgtg catatttgtt actttacttt tgctgtttat 1900

 acttgagacc aacttttcaa tgtgattctt ctaaagcact ggtttcaaga 1950

 atatggaggc tggaaggaaa taaacattac ggtacagaca tggagatgta 2000

 aaatgagttt gtattattac aaatattgtc atctttttct agagttatct 2050

 tctttattat tcctagtctt tccagtcaac atcgtggatg tagtgattaa 2100

 atatatctag aactatcatt tttacactat tgtgaatatt tggaattgaa 2150

 cgactgtata ttgctaagag ggcccaaaga attggaatcc tccttaattt 2200

 aattgctttg aagcatagct acaatttgtt tttgcatttt tgttttgaaa 2250

 gtttaacaaa tgactgtatc taggcatttc attatgcttt gaactttagt 2300

 ttgcctgcag tttcttgtgt agatttgaaa attgtatacc aatgtgtttt 2350

 ctgtagactc taagatacac tgcactttgt ttagaaaaaa aactgaagat 2400

 gaaatatata ttgtaaagaa gggatattaa gaatcttaga taacttcttg 2450

 aaaaagatgg cttatgtcat cagtaaagta cctttatgtt atgaggatat 2500

 aatgtgtgct ttattgaatt agaaaattag tgaccattat tcacaggtgg 2550

 acaaatgttg tcctgttaat ttataggagt tttttgggga tgtggaggta 2600

 gttgggtaga aaaattatta gaacattcac ttttgttaac agtatttctc 2650

 ttttattctg ttatatagtg gatgatatac acagtggcaa aacaaaagta 2700

 cattgcttaa aatatatagt gaaaaatgtc actatatctt cccatttaac 2750

 attgtttttg tatattgggt gtagatttct gacatcaaaa cttggaccct 2800

 tggaaaacaa aagttttaat taaaaaaaat ccttgtgact tacaatttgc 2850

 acaatatttc ttttgttgta ctttatatct tgtttacaat aaagaattc 2899

<210> 6326
<211> 480
<212> PRT
<213> Homo sapien

<400> 6326
 Met Leu Asn Phe Gly Ala Ser Leu Gln Gln Thr Ala Glu Glu Arg
   1               5                  10                  15

 Met Glu Met Ile Ser Glu Arg Pro Lys Glu Ser Met Tyr Ser Trp
                  20                  25                  30

 Asn Lys Thr Ala Glu Lys Ser Asp Phe Glu Ala Val Glu Ala Leu
                  35                  40                  45

 Met Ser Met Ser Cys Ser Trp Lys Ser Asp Phe Lys Lys Tyr Val
                  50                  55                  60

 Glu Asn Arg Pro Val Thr Pro Val Ser Asp Leu Ser Glu Glu Glu
                  65                  70                  75

 Asn Leu Leu Pro Gly Thr Pro Asp Phe His Thr Ile Pro Ala Phe
                  80                  85                  90

 Cys Leu Thr Pro Pro Tyr Ser Pro Ser Asp Phe Glu Pro Ser Gln
                  95                 100                 105

 Val Ser Asn Leu Met Ala Pro Ala Pro Ser Thr Val His Phe Lys
                 110                 115                 120

 Ser Leu Ser Asp Thr Ala Lys Pro His Ile Ala Ala Pro Phe Lys
                 125                 130                 135

 Glu Glu Glu Lys Ser Pro Val Ser Ala Pro Lys Leu Pro Lys Ala
                 140                 145                 150

 Gln Ala Thr Ser Val Ile Arg His Thr Ala Asp Ala Gln Leu Cys
                 155                 160                 165

 Asn His Gln Thr Cys Pro Met Lys Ala Ala Ser Ile Leu Asn Tyr
                 170                 175                 180

 Gln Asn Asn Ser Phe Arg Arg Arg Thr His Leu Asn Val Glu Ala
                 185                 190                 195

 Ala Arg Lys Asn Ile Pro Cys Ala Ala Val Ser Pro Asn Arg Ser
                 200                 205                 210

 Lys Cys Glu Arg Asn Thr Val Ala Asp Val Asp Glu Lys Ala Ser
                 215                 220                 225

 Ala Ala Leu Tyr Asp Phe Ser Val Pro Ser Ser Glu Thr Val Ile
                 230                 235                 240

 Cys Arg Ser Gln Pro Ala Pro Val Ser Pro Gln Gln Lys Ser Val
                 245                 250                 255

 Leu Val Ser Pro Pro Ala Val Ser Ala Gly Gly Val Pro Pro Met
                 260                 265                 270

 Pro Val Ile Cys Gln Met Val Pro Leu Pro Ala Asn Asn Pro Val
                 275                 280                 285

 Val Thr Thr Val Val Pro Ser Thr Pro Pro Ser Gln Pro Pro Ala
                 290                 295                 300

 Val Cys Pro Pro Val Val Phe Met Gly Thr Gln Val Pro Lys Gly
                 305                 310                 315

 Ala Val Met Phe Val Val Pro Gln Pro Val Val Gln Ser Ser Lys
                 320                 325                 330

 Pro Pro Val Val Ser Pro Asn Gly Thr Arg Leu Ser Pro Ile Ala
                 335                 340                 345

 Pro Ala Pro Gly Phe Ser Pro Ser Ala Ala Lys Val Thr Pro Gln
                 350                 355                 360

 Ile Asp Ser Ser Arg Ile Arg Ser His Ile Cys Ser His Pro Gly
                 365                 370                 375

 Cys Gly Lys Thr Tyr Phe Lys Ser Ser His Leu Lys Ala His Thr
                 380                 385                 390

 Arg Thr His Thr Gly Glu Lys Pro Phe Ser Cys Ser Trp Lys Gly
                 395                 400                 405

 Cys Glu Arg Arg Phe Ala Arg Ser Asp Glu Leu Ser Arg His Arg
                 410                 415                 420

 Arg Thr His Thr Gly Glu Lys Lys Phe Ala Cys Pro Met Cys Asp
                 425                 430                 435

 Arg Arg Phe Met Arg Ser Asp His Leu Thr Lys His Ala Arg Arg
                 440                 445                 450

 His Leu Ser Ala Lys Lys Leu Pro Asn Trp Gln Met Glu Val Ser
                 455                 460                 465

 Lys Leu Asn Asp Ile Ala Leu Pro Pro Thr Pro Ala Pro Thr Gln
                 470                 475                 480

<210> 6327
<211> 938
<212> DNA
<213> Homo sapien

<400> 6327
 caagagagag agagaggtgc aagccccaaa gcgagcgaca tgtccctttg 50

 gggagcagtc cctctgcacc ccagagtgag gaggacgcag gggtcagagg 100

 tggctacagg gcaggcagag gaggcacctg tagggggtgg tgggctggtg 150

 gcccaggaga agtcaggaag ggagcccagc tggtgacaag agagcccaga 200

 ggtgcctggg gctgagtgtg agagcccgga agatttcagc catgcctcac 250

 agctccgaca gcagtgactc cagcttcagc cgctctcctc cccctggcaa 300

 acaggactca tctgatgatg tgagaagagt tcagaggagg gagaaaaatc 350

 gtattgccgc ccagaagagc cgacagaggc agacacagaa ggccgacacc 400

 ctgcacctgg agagcgaaga cctggagaaa cagaacgcgg ctctacgcaa 450

 ggagatcaag cagctcacag aggaactgaa gtacttcacg tcggtgctga 500

 acagccacga gcccctgtgc tcggtgctgg ccgccagcac gccctcgccc 550

 cccgaggtgg tgtacagcgc ccacgcattc caccaacctc atgtcagctc 600

 cccgcgcttc cagccctgag cttccgatgc ggggagagca gagcctcggg 650

 aggggcacac agactgtggc agagctgcgc ccatcccgca gaggcccctg 700

 tccacctgga gacccggaga cagaggcctg gacaaggagt gaacacggga 750

 actgtcacga ctggaagggc gtgaggcctc ccagcagtgc cgcagcgttt 800

 cgaggggcgt gtgctggacc ccaccactgt gggttgcagg cccaatgcag 850

 aagagtatta agaaagatgc tcaagtccca tggcacagag caaggcgggc 900

 agggaacggt tatttttcta aataaatgct ttaaaaga 938

<210> 6328
<211> 125
<212> PRT
<213> Homo sapien

<400> 6328
 Met Pro His Ser Ser Asp Ser Ser Asp Ser Ser Phe Ser Arg Ser
   1               5                  10                  15

 Pro Pro Pro Gly Lys Gln Asp Ser Ser Asp Asp Val Arg Arg Val
                  20                  25                  30

 Gln Arg Arg Glu Lys Asn Arg Ile Ala Ala Gln Lys Ser Arg Gln
                  35                  40                  45

 Arg Gln Thr Gln Lys Ala Asp Thr Leu His Leu Glu Ser Glu Asp
                  50                  55                  60

 Leu Glu Lys Gln Asn Ala Ala Leu Arg Lys Glu Ile Lys Gln Leu
                  65                  70                  75

 Thr Glu Glu Leu Lys Tyr Phe Thr Ser Val Leu Asn Ser His Glu
                  80                  85                  90

 Pro Leu Cys Ser Val Leu Ala Ala Ser Thr Pro Ser Pro Pro Glu
                  95                 100                 105

 Val Val Tyr Ser Ala His Ala Phe His Gln Pro His Val Ser Ser
                 110                 115                 120

 Pro Arg Phe Gln Pro
                 125

<210> 6329
<211> 1935
<212> DNA
<213> Homo sapien

<400> 6329
 ctggtcccga gcacgagctg tgaggggatt cacttgtgtg cggaactcct 50

 cggaaccatg gcgtcccttt cccttgcacc tgttaacatc tttaaggcag 100

 gagctgatga agagagagca gagacagctc gtctgacttc ttttattggt 150

 gccatcgcca ttggagactt ggtaaagagc accttgggac ccaaaggcat 200

 ggacaaaatt cttctaagca gtggacgaga tgcctctctt atggtaacca 250

 atgatggtgc cactattcta aaaaacattg gtgttgacaa tccagcagct 300

 aaagttttag ttgatatgtc aagggttcaa gatgatgaag ttggtgatgg 350

 cactacctct gttaccgttt tagcagcaga attattaagg gaagcagaat 400

 ctttaattgc aaaaaagatt catccacaga ccatcatagc gggttggaga 450

 gaagccacga aggctgcaag agaggcgctg ttgagttctg cagttgatca 500

 tggttccgat gaagttaaat tccgtcaaga tttaatgaat attgcgggca 550

 caacattatc ctcaaaactt cttactcatc acaaagacca ctttacaaag 600

 ttagctgtag aagcagttct cagactgaaa ggctctggca acctggaggc 650

 aattcatatt atcaagaagc taggaggaag tttggcagat tcctatttag 700

 atgaaggctt cctgttggat aaaaaaattg gagtaaatca accaaaacga 750

 attgaaaatg ctaaaattct tattgcaaat actggtatgg atacagacaa 800

 aataaagata tttggttccc gggtaagagt tgactctaca gcaaaggttg 850

 cagaaataga acatgcggaa aaggaaaaaa tgaaggagaa agttgaacgt 900

 attcttaagc atggaataaa ttgctttatt aacaggcaat taatttataa 950

 ttatcctgaa cagctctttg gtgctgctgg tgtcatggct attgagcatg 1000

 cagattttgc aggtgtggaa cgcctagctc ttgtcacagg tggtgaaatt 1050

 gcctctacct ttgatcaccc agaactggtg aagcttggaa gttgcaaact 1100

 tatcgaggaa gtcatgattg gagaagacaa actcattcac ttttctgggg 1150

 ttgcccttgg tgaggcttgt accattgttt tgcgtggtgc cactcaacaa 1200

 attttagatg aagcagaaag atcattgcat gatgctcttt gtgttcttgc 1250

 gcaaactgta aaggactcta gaacagttta tggaggaggc tgttctgaga 1300

 tgttgatggc tcatgctgtg acacagcttg ccaatagaac accaggcaaa 1350

 gaagctgttg caatggagtc ttatgctaaa gcactgagaa tgttgccaac 1400

 catcatagct gacaatgcag gctatgacag tgcagacctg gtggcacagc 1450

 tcagggctgc tcacagtgaa ggcaatacca ctgctggatt ggatatgagg 1500

 gaaggcacca ttggagatat ggctatcctg ggtataacag aaagttttca 1550

 agtgaagcga caggttcttc tgagtgcagc tgaagcagca gaggtgattc 1600

 tgcgtgtgga caacatcatc aaagcggcac ccaggaaacg tgtccctgat 1650

 caccacccct gttaagcatt cccacgtgct gtcgatcttt ggaccagttt 1700

 ctagcaaagt tgtgtttgaa agatactcta ttaaagaaga ctgtggaatc 1750

 tgtttatcgg tgcccattat atccttaagt ttggatattt agctgacctt 1800

 cgctttaaca taggtctaat ttatttgccg tgtcattttc catacaaatc 1850

 agttgattta aaggagttca tttcgcatac tgggcattaa aataaaaatt 1900

 tgaacaatga aaggaaaaaa aggagaaaaa aaaaa 1935

<210> 6330
<211> 535
<212> PRT
<213> Homo sapien

<400> 6330
 Met Ala Ser Leu Ser Leu Ala Pro Val Asn Ile Phe Lys Ala Gly
   1               5                  10                  15

 Ala Asp Glu Glu Arg Ala Glu Thr Ala Arg Leu Thr Ser Phe Ile
                  20                  25                  30

 Gly Ala Ile Ala Ile Gly Asp Leu Val Lys Ser Thr Leu Gly Pro
                  35                  40                  45

 Lys Gly Met Asp Lys Ile Leu Leu Ser Ser Gly Arg Asp Ala Ser
                  50                  55                  60

 Leu Met Val Thr Asn Asp Gly Ala Thr Ile Leu Lys Asn Ile Gly
                  65                  70                  75

 Val Asp Asn Pro Ala Ala Lys Val Leu Val Asp Met Ser Arg Val
                  80                  85                  90

 Gln Asp Asp Glu Val Gly Asp Gly Thr Thr Ser Val Thr Val Leu
                  95                 100                 105

 Ala Ala Glu Leu Leu Arg Glu Ala Glu Ser Leu Ile Ala Lys Lys
                 110                 115                 120

 Ile His Pro Gln Thr Ile Ile Ala Gly Trp Arg Glu Ala Thr Lys
                 125                 130                 135

 Ala Ala Arg Glu Ala Leu Leu Ser Ser Ala Val Asp His Gly Ser
                 140                 145                 150

 Asp Glu Val Lys Phe Arg Gln Asp Leu Met Asn Ile Ala Gly Thr
                 155                 160                 165

 Thr Leu Ser Ser Lys Leu Leu Thr His His Lys Asp His Phe Thr
                 170                 175                 180

 Lys Leu Ala Val Glu Ala Val Leu Arg Leu Lys Gly Ser Gly Asn
                 185                 190                 195

 Leu Glu Ala Ile His Ile Ile Lys Lys Leu Gly Gly Ser Leu Ala
                 200                 205                 210

 Asp Ser Tyr Leu Asp Glu Gly Phe Leu Leu Asp Lys Lys Ile Gly
                 215                 220                 225

 Val Asn Gln Pro Lys Arg Ile Glu Asn Ala Lys Ile Leu Ile Ala
                 230                 235                 240

 Asn Thr Gly Met Asp Thr Asp Lys Ile Lys Ile Phe Gly Ser Arg
                 245                 250                 255

 Val Arg Val Asp Ser Thr Ala Lys Val Ala Glu Ile Glu His Ala
                 260                 265                 270

 Glu Lys Glu Lys Met Lys Glu Lys Val Glu Arg Ile Leu Lys His
                 275                 280                 285

 Gly Ile Asn Cys Phe Ile Asn Arg Gln Leu Ile Tyr Asn Tyr Pro
                 290                 295                 300

 Glu Gln Leu Phe Gly Ala Ala Gly Val Met Ala Ile Glu His Ala
                 305                 310                 315

 Asp Phe Ala Gly Val Glu Arg Leu Ala Leu Val Thr Gly Gly Glu
                 320                 325                 330

 Ile Ala Ser Thr Phe Asp His Pro Glu Leu Val Lys Leu Gly Ser
                 335                 340                 345

 Cys Lys Leu Ile Glu Glu Val Met Ile Gly Glu Asp Lys Leu Ile
                 350                 355                 360

 His Phe Ser Gly Val Ala Leu Gly Glu Ala Cys Thr Ile Val Leu
                 365                 370                 375

 Arg Gly Ala Thr Gln Gln Ile Leu Asp Glu Ala Glu Arg Ser Leu
                 380                 385                 390

 His Asp Ala Leu Cys Val Leu Ala Gln Thr Val Lys Asp Ser Arg
                 395                 400                 405

 Thr Val Tyr Gly Gly Gly Cys Ser Glu Met Leu Met Ala His Ala
                 410                 415                 420

 Val Thr Gln Leu Ala Asn Arg Thr Pro Gly Lys Glu Ala Val Ala
                 425                 430                 435

 Met Glu Ser Tyr Ala Lys Ala Leu Arg Met Leu Pro Thr Ile Ile
                 440                 445                 450

 Ala Asp Asn Ala Gly Tyr Asp Ser Ala Asp Leu Val Ala Gln Leu
                 455                 460                 465

 Arg Ala Ala His Ser Glu Gly Asn Thr Thr Ala Gly Leu Asp Met
                 470                 475                 480

 Arg Glu Gly Thr Ile Gly Asp Met Ala Ile Leu Gly Ile Thr Glu
                 485                 490                 495

 Ser Phe Gln Val Lys Arg Gln Val Leu Leu Ser Ala Ala Glu Ala
                 500                 505                 510

 Ala Glu Val Ile Leu Arg Val Asp Asn Ile Ile Lys Ala Ala Pro
                 515                 520                 525

 Arg Lys Arg Val Pro Asp His His Pro Cys
                 530                 535

<210> 6331
<211> 1821
<212> DNA
<213> Homo sapien

<400> 6331
 cgcgtgaact gcttcctgca ggctggccat ggcgcttcac gttcccaagg 50

 ctccgggctt tgcccagatg ctcaaggagg gagcgaaaca cttttcagga 100

 ttagaagagg ctgtgtatag aaacatacaa gcttgcaagg agcttgccca 150

 aaccactcgt acagcatatg gaccaaaagg aatgaacaaa atggttatca 200

 accacttgga gaagttgttt gtgacaaacg atgcagcaac tattttaaga 250

 gaactagaag tacagcatcc tgctgcaaaa atgattgtaa tggcttctca 300

 tatgcaagag caagaagttg gagatggcac aaactttgtt ctggtatttg 350

 ctggagctct cctggaatta gctgaagaac ttctgaggat tggcctgtca 400

 gtttcagagg tcatagaagg ttatgaaata gcctgcagaa aagctcatga 450

 gattcttcct aatttggtat gttgttctgc aaaaaacctt cgagatattg 500

 atgaagtctc atctctactt cgtacctcca taatgagtaa acaatatggt 550

 aatgaagtat ttctggccaa gcttattgct caggcatgcg tatctatttt 600

 tcctgattcc ggccatttca atgttgataa catcagagtt tgtaaaattc 650

 tgggctctgg tatcagttcc tcttcagtat tgcatggcat ggtttttaag 700

 aaggaaaccg aaggtgatgt aacatctgtc aaagatgcaa aaatagcagt 750

 gtactcttgt ccttttgatg gcatgataac agaaactaag ggaacagtgt 800

 tgataaagac tgctgaagaa ttgatgaatt ttagtaaggg agaagaaaac 850

 ctcatggatg cacaagtcaa agctattgct gatactggtg caaatgtcgt 900

 agtaacaggt ggcaaagtgg cagacatggc tcttcattat gcaaataaat 950

 ataatatcat gttagtgagg ctaaactcaa aatgggatct ccgaagactt 1000

 tgtaaaactg ttggtgctac agctcttcct agattgacac ctcctgtcct 1050

 tgaagaaatg ggacactgtg acagtgttta cctctcagaa gttggagata 1100

 ctcaggtggt ggtttttaag catgaaaagg aagatggcgc catttctacc 1150

 atagtacttc gaggctctac agacaatctg atggatgaca tagaaagggt 1200

 agtagacgat ggtgttaata ctttcaaagt tcttacaagg gataaacgtc 1250

 ttgtacccgg aggtggagca acagaaattg aattagccaa acagatcaca 1300

 tcatatggag agacatgtcc tggacttgaa cagtatgcta ttaagaagtt 1350

 tgctgaggca tttgaagcta ttccccgcgc actggcagaa aactctggag 1400

 ttaaggccaa tgaagtaatc tctaaacttt atgcagtaca tcaagaagga 1450

 aataaaaacg ttggattaga tattgaggct gaagtccctg ctgtaaagga 1500

 catgctggaa gctggtattc tagatactta cctgggaaaa tattgggcta 1550

 tcaaactcgc tactaatgct gcagtcactg tacttagagt ggatcagatc 1600

 atcatggcaa aaccagctgg tgggcccaag cctccaagtg ggaagaaaga 1650

 ctgggatgat gaccaaaatg attgaaattg gcttaatttt tactgtaggt 1700

 gaaggctgta tttgtagtag tactcaagaa tcacctgatg ttttcttatt 1750

 ctccttaaat taagagttat tttgtgtttg tattcttggc tggatgttat 1800

 aataaacata ttgttactgt c 1821

<210> 6332
<211> 548
<212> PRT
<213> Homo sapien

<400> 6332
 Met Ala Leu His Val Pro Lys Ala Pro Gly Phe Ala Gln Met Leu
   1               5                  10                  15

 Lys Glu Gly Ala Lys His Phe Ser Gly Leu Glu Glu Ala Val Tyr
                  20                  25                  30

 Arg Asn Ile Gln Ala Cys Lys Glu Leu Ala Gln Thr Thr Arg Thr
                  35                  40                  45

 Ala Tyr Gly Pro Lys Gly Met Asn Lys Met Val Ile Asn His Leu
                  50                  55                  60

 Glu Lys Leu Phe Val Thr Asn Asp Ala Ala Thr Ile Leu Arg Glu
                  65                  70                  75

 Leu Glu Val Gln His Pro Ala Ala Lys Met Ile Val Met Ala Ser
                  80                  85                  90

 His Met Gln Glu Gln Glu Val Gly Asp Gly Thr Asn Phe Val Leu
                  95                 100                 105

 Val Phe Ala Gly Ala Leu Leu Glu Leu Ala Glu Glu Leu Leu Arg
                 110                 115                 120

 Ile Gly Leu Ser Val Ser Glu Val Ile Glu Gly Tyr Glu Ile Ala
                 125                 130                 135

 Cys Arg Lys Ala His Glu Ile Leu Pro Asn Leu Val Cys Cys Ser
                 140                 145                 150

 Ala Lys Asn Leu Arg Asp Ile Asp Glu Val Ser Ser Leu Leu Arg
                 155                 160                 165

 Thr Ser Ile Met Ser Lys Gln Tyr Gly Asn Glu Val Phe Leu Ala
                 170                 175                 180

 Lys Leu Ile Ala Gln Ala Cys Val Ser Ile Phe Pro Asp Ser Gly
                 185                 190                 195

 His Phe Asn Val Asp Asn Ile Arg Val Cys Lys Ile Leu Gly Ser
                 200                 205                 210

 Gly Ile Ser Ser Ser Ser Val Leu His Gly Met Val Phe Lys Lys
                 215                 220                 225

 Glu Thr Glu Gly Asp Val Thr Ser Val Lys Asp Ala Lys Ile Ala
                 230                 235                 240

 Val Tyr Ser Cys Pro Phe Asp Gly Met Ile Thr Glu Thr Lys Gly
                 245                 250                 255

 Thr Val Leu Ile Lys Thr Ala Glu Glu Leu Met Asn Phe Ser Lys
                 260                 265                 270

 Gly Glu Glu Asn Leu Met Asp Ala Gln Val Lys Ala Ile Ala Asp
                 275                 280                 285

 Thr Gly Ala Asn Val Val Val Thr Gly Gly Lys Val Ala Asp Met
                 290                 295                 300

 Ala Leu His Tyr Ala Asn Lys Tyr Asn Ile Met Leu Val Arg Leu
                 305                 310                 315

 Asn Ser Lys Trp Asp Leu Arg Arg Leu Cys Lys Thr Val Gly Ala
                 320                 325                 330

 Thr Ala Leu Pro Arg Leu Thr Pro Pro Val Leu Glu Glu Met Gly
                 335                 340                 345

 His Cys Asp Ser Val Tyr Leu Ser Glu Val Gly Asp Thr Gln Val
                 350                 355                 360

 Val Val Phe Lys His Glu Lys Glu Asp Gly Ala Ile Ser Thr Ile
                 365                 370                 375

 Val Leu Arg Gly Ser Thr Asp Asn Leu Met Asp Asp Ile Glu Arg
                 380                 385                 390

 Val Val Asp Asp Gly Val Asn Thr Phe Lys Val Leu Thr Arg Asp
                 395                 400                 405

 Lys Arg Leu Val Pro Gly Gly Gly Ala Thr Glu Ile Glu Leu Ala
                 410                 415                 420

 Lys Gln Ile Thr Ser Tyr Gly Glu Thr Cys Pro Gly Leu Glu Gln
                 425                 430                 435

 Tyr Ala Ile Lys Lys Phe Ala Glu Ala Phe Glu Ala Ile Pro Arg
                 440                 445                 450

 Ala Leu Ala Glu Asn Ser Gly Val Lys Ala Asn Glu Val Ile Ser
                 455                 460                 465

 Lys Leu Tyr Ala Val His Gln Glu Gly Asn Lys Asn Val Gly Leu
                 470                 475                 480

 Asp Ile Glu Ala Glu Val Pro Ala Val Lys Asp Met Leu Glu Ala
                 485                 490                 495

 Gly Ile Leu Asp Thr Tyr Leu Gly Lys Tyr Trp Ala Ile Lys Leu
                 500                 505                 510

 Ala Thr Asn Ala Ala Val Thr Val Leu Arg Val Asp Gln Ile Ile
                 515                 520                 525

 Met Ala Lys Pro Ala Gly Gly Pro Lys Pro Pro Ser Gly Lys Lys
                 530                 535                 540

 Asp Trp Asp Asp Asp Gln Asn Asp
                 545

<210> 6333
<211> 3448
<212> DNA
<213> Homo sapien

<400> 6333
 gttcagcgcc ggcgccggtg tgcgagccgc ggcagagtga ggcaggcaac 50

 ccgaggtgcg gagcgacctg cggaggctga gccccgcttt ctcccagggt 100

 ttcttatcag ccagccgccg ctgtccccgg gggagtagga ggctcctgac 150

 aggccgcggc tgtctgtgtg tccttctgag tgtcagagga acggccagac 200

 cccgcgggcc ggagcagaac gcggccaggg cagaaagcgg cggcaggaga 250

 agcaggcagg gggccggagg acgcagaccg agacccgagg cggaggcgga 300

 ccgcgagccg gccatgtcgg tggtggggtt ggacgtgggc tcgcagagct 350

 gctacatcgc ggtagcccgg gccgggggca tcgagaccat cgccaatgag 400

 ttcagcgacc ggtgcacccc gtcagtcata tcatttggat caaaaaatag 450

 aacaatcgga gttgcagcca aaaatcagca aatcactcat gcaaacaata 500

 cggtgtctaa cttcaaaaga tttcatggcc gagcattcaa cgaccccttc 550

 attcaaaagg agaaggaaaa cttgagttac gatttggttc cattgaaaaa 600

 tggtggagtt ggaataaagg taatgtacat gggtgaagaa catctattta 650

 gtgtggagca gataacagcc atgttgttga ctaagctgaa ggaaactgct 700

 gaaaacagcc tcaagaaacc agtaacagat tgtgttattt cagtcccctc 750

 cttctttaca gatgctgaga ggcgatctgt gttagatgct gcacagattg 800

 ttggcctaaa ctgtttaaga cttatgaatg acatgacagc tgttgctttg 850

 aattacggaa tttataagca ggatctccca agcctggatg agaaacctcg 900

 gatagtggtt tttgttgata tgggacattc agcttttcaa gtgtctgctt 950

 gtgcttttaa caagggaaaa ttgaaggtac tgggaacagc ttttgatcct 1000

 ttcttaggag gaaaaaactt cgatgaaaag ttagtggaac atttctgtgc 1050

 agaatttaaa actaagtaca agttggatgc aaaatccaaa atacgagcac 1100

 tcctacgtct gtatcaggaa tgtgaaaaac tgaaaaagct aatgagctct 1150

 aacagcacag accttccact gaatatcgaa tgctttatga atgataaaga 1200

 tgtttccgga aagatgaaca ggtcacaatt tgaagaactc tgtgctgaac 1250

 ttctgcaaaa gatagaagta cccctttatt cactgttgga acaaactcat 1300

 ctcaaagtag aagatgtgag tgcagttgag attgttggag gcgctacacg 1350

 aattccagct gtgaaggaaa gaattgccaa attctttgga aaagatatta 1400

 gcacaacact caatgcagat gaagcagtag ccagaggatg tgcattacag 1450

 tgtgcaatac tttccccggc atttaaagtt agagaatttt ccgtcacaga 1500

 tgcagttcct tttccaatat ctctgatctg gaaccatgat tcagaagata 1550

 ctgaaggtgt tcatgaagtc tttagtcgaa accatgctgc tcctttctcc 1600

 aaagttctca cctttctgag aagggggcct tttgagctag aagctttcta 1650

 ttctgatccc caaggagttc catatccaga agcaaaaata ggccgctttg 1700

 tagttcagaa tgtttctgca cagaaagatg gagaaaaatc tagagtaaaa 1750

 gtcaaagtgc gagtcaacac ccatggcatt ttcaccatct ctacggcatc 1800

 tatggtggag aaagtcccaa ctgaggagaa tgaaatgtct tctgaagctg 1850

 acatggagtg tctgaatcag agaccaccag aaaacccaga cactgatgca 1900

 aatgaaaaaa aagttgacca gcctccagaa gctaaaaagc ccaaaataaa 1950

 ggtggtgaat gttgagctgc ctattgaagc caacttggtc tggcagttag 2000

 ggaaagacct tcttaacatg tatattgaga cagagggtaa gatgataatg 2050

 caagataaat tggaaaaaga aaggaatgat gctaaaaatg cagttgagga 2100

 atatgtgtat gagttcagag acaagctgtg tggaccatat gaaaaattta 2150

 tatgtgagca ggatcatcaa aattttttga gactcctcac agaaactgaa 2200

 gactggctgt atgaagaagg agaggaccaa gctaaacaag catatgttga 2250

 caagttggaa gaattaatga aaattggcac tccagttaaa gttcggtttc 2300

 aggaagctga agaacggcca aaaatgtttg aagaactagg acagaggctg 2350

 cagcattatg ccaagatagc agctgacttc agaaataagg atgagaaata 2400

 caaccatatt gatgagtctg aaatgaaaaa agtggagaag tctgttaatg 2450

 aagtgatgga atggatgaat aatgtcatga atgctcaggc taaaaagagt 2500

 cttgatcagg atccagttgt acgtgctcag gaaattaaaa caaaaatcaa 2550

 ggaattgaac aacacatgtg aacccgttgt aacacaaccg aaaccaaaaa 2600

 ttgaatcacc caaactggaa agaactccaa atggcccaaa tattgataaa 2650

 aaggaagaag atttagaaga caaaaacaat tttggtgctg aacctccaca 2700

 tcagaatggt gaatgttacc ctaatgagaa aaattctgtt aatatggact 2750

 tggactagat aaccttaaat tggcctattc cttcaattaa taaaatattt 2800

 ttgccatagt atgtgactct acataacata ctgaaactat ttatattttc 2850

 ttttttaagg atatttagaa attttgtgta ttatatggaa aaagaaaaaa 2900

 agcttaagtc tgtagtcttt atgatcctaa aagggaaaat tgccttggta 2950

 actttcagat tcctgtggaa ttgtgaattc atactaagct ttctgtgcag 3000

 tctcaccatt tgcatcactg aggatgaaac tgacttttgt cttttggaga 3050

 aaaaaaactg tactgttgtt caagagggct gtgattaaaa tctttaagca 3100

 tttgttcctg ccaaggtagt tttcttgcat tttgctctcc attcagcatg 3150

 tgtgtgggtg tggatgttta taaacaagac taagtctgac ttcataaggg 3200

 ctttctaaaa ccatttctgt ccaagagaaa atgacttttt gctttgatat 3250

 taaaaattca atgagtaaaa caaaagctag tcaaatgtgt tagcagcatg 3300

 cagaacaaaa actttaaact ttctctctca ctatacagta tattgtcaat 3350

 gtgaaagtgt ggaatggaag aaatgtcgat cctgttgtaa ctgattgtga 3400

 acacttttat gagctttaaa ataaagttca tcttatggtg tcatttct 3448

<210> 6334
<211> 814
<212> PRT
<213> Homo sapien

<400> 6334
 Met Ser Val Val Gly Leu Asp Val Gly Ser Gln Ser Cys Tyr Ile
   1               5                  10                  15

 Ala Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Phe
                  20                  25                  30

 Ser Asp Arg Cys Thr Pro Ser Val Ile Ser Phe Gly Ser Lys Asn
                  35                  40                  45

 Arg Thr Ile Gly Val Ala Ala Lys Asn Gln Gln Ile Thr His Ala
                  50                  55                  60

 Asn Asn Thr Val Ser Asn Phe Lys Arg Phe His Gly Arg Ala Phe
                  65                  70                  75

 Asn Asp Pro Phe Ile Gln Lys Glu Lys Glu Asn Leu Ser Tyr Asp
                  80                  85                  90

 Leu Val Pro Leu Lys Asn Gly Gly Val Gly Ile Lys Val Met Tyr
                  95                 100                 105

 Met Gly Glu Glu His Leu Phe Ser Val Glu Gln Ile Thr Ala Met
                 110                 115                 120

 Leu Leu Thr Lys Leu Lys Glu Thr Ala Glu Asn Ser Leu Lys Lys
                 125                 130                 135

 Pro Val Thr Asp Cys Val Ile Ser Val Pro Ser Phe Phe Thr Asp
                 140                 145                 150

 Ala Glu Arg Arg Ser Val Leu Asp Ala Ala Gln Ile Val Gly Leu
                 155                 160                 165

 Asn Cys Leu Arg Leu Met Asn Asp Met Thr Ala Val Ala Leu Asn
                 170                 175                 180

 Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Ser Leu Asp Glu Lys Pro
                 185                 190                 195

 Arg Ile Val Val Phe Val Asp Met Gly His Ser Ala Phe Gln Val
                 200                 205                 210

 Ser Ala Cys Ala Phe Asn Lys Gly Lys Leu Lys Val Leu Gly Thr
                 215                 220                 225

 Ala Phe Asp Pro Phe Leu Gly Gly Lys Asn Phe Asp Glu Lys Leu
                 230                 235                 240

 Val Glu His Phe Cys Ala Glu Phe Lys Thr Lys Tyr Lys Leu Asp
                 245                 250                 255

 Ala Lys Ser Lys Ile Arg Ala Leu Leu Arg Leu Tyr Gln Glu Cys
                 260                 265                 270

 Glu Lys Leu Lys Lys Leu Met Ser Ser Asn Ser Thr Asp Leu Pro
                 275                 280                 285

 Leu Asn Ile Glu Cys Phe Met Asn Asp Lys Asp Val Ser Gly Lys
                 290                 295                 300

 Met Asn Arg Ser Gln Phe Glu Glu Leu Cys Ala Glu Leu Leu Gln
                 305                 310                 315

 Lys Ile Glu Val Pro Leu Tyr Ser Leu Leu Glu Gln Thr His Leu
                 320                 325                 330

 Lys Val Glu Asp Val Ser Ala Val Glu Ile Val Gly Gly Ala Thr
                 335                 340                 345

 Arg Ile Pro Ala Val Lys Glu Arg Ile Ala Lys Phe Phe Gly Lys
                 350                 355                 360

 Asp Ile Ser Thr Thr Leu Asn Ala Asp Glu Ala Val Ala Arg Gly
                 365                 370                 375

 Cys Ala Leu Gln Cys Ala Ile Leu Ser Pro Ala Phe Lys Val Arg
                 380                 385                 390

 Glu Phe Ser Val Thr Asp Ala Val Pro Phe Pro Ile Ser Leu Ile
                 395                 400                 405

 Trp Asn His Asp Ser Glu Asp Thr Glu Gly Val His Glu Val Phe
                 410                 415                 420

 Ser Arg Asn His Ala Ala Pro Phe Ser Lys Val Leu Thr Phe Leu
                 425                 430                 435

 Arg Arg Gly Pro Phe Glu Leu Glu Ala Phe Tyr Ser Asp Pro Gln
                 440                 445                 450

 Gly Val Pro Tyr Pro Glu Ala Lys Ile Gly Arg Phe Val Val Gln
                 455                 460                 465

 Asn Val Ser Ala Gln Lys Asp Gly Glu Lys Ser Arg Val Lys Val
                 470                 475                 480

 Lys Val Arg Val Asn Thr His Gly Ile Phe Thr Ile Ser Thr Ala
                 485                 490                 495

 Ser Met Val Glu Lys Val Pro Thr Glu Glu Asn Glu Met Ser Ser
                 500                 505                 510

 Glu Ala Asp Met Glu Cys Leu Asn Gln Arg Pro Pro Glu Asn Pro
                 515                 520                 525

 Asp Thr Asp Ala Asn Glu Lys Lys Val Asp Gln Pro Pro Glu Ala
                 530                 535                 540

 Lys Lys Pro Lys Ile Lys Val Val Asn Val Glu Leu Pro Ile Glu
                 545                 550                 555

 Ala Asn Leu Val Trp Gln Leu Gly Lys Asp Leu Leu Asn Met Tyr
                 560                 565                 570

 Ile Glu Thr Glu Gly Lys Met Ile Met Gln Asp Lys Leu Glu Lys
                 575                 580                 585

 Glu Arg Asn Asp Ala Lys Asn Ala Val Glu Glu Tyr Val Tyr Glu
                 590                 595                 600

 Phe Arg Asp Lys Leu Cys Gly Pro Tyr Glu Lys Phe Ile Cys Glu
                 605                 610                 615

 Gln Asp His Gln Asn Phe Leu Arg Leu Leu Thr Glu Thr Glu Asp
                 620                 625                 630

 Trp Leu Tyr Glu Glu Gly Glu Asp Gln Ala Lys Gln Ala Tyr Val
                 635                 640                 645

 Asp Lys Leu Glu Glu Leu Met Lys Ile Gly Thr Pro Val Lys Val
                 650                 655                 660

 Arg Phe Gln Glu Ala Glu Glu Arg Pro Lys Met Phe Glu Glu Leu
                 665                 670                 675

 Gly Gln Arg Leu Gln His Tyr Ala Lys Ile Ala Ala Asp Phe Arg
                 680                 685                 690

 Asn Lys Asp Glu Lys Tyr Asn His Ile Asp Glu Ser Glu Met Lys
                 695                 700                 705

 Lys Val Glu Lys Ser Val Asn Glu Val Met Glu Trp Met Asn Asn
                 710                 715                 720

 Val Met Asn Ala Gln Ala Lys Lys Ser Leu Asp Gln Asp Pro Val
                 725                 730                 735

 Val Arg Ala Gln Glu Ile Lys Thr Lys Ile Lys Glu Leu Asn Asn
                 740                 745                 750

 Thr Cys Glu Pro Val Val Thr Gln Pro Lys Pro Lys Ile Glu Ser
                 755                 760                 765

 Pro Lys Leu Glu Arg Thr Pro Asn Gly Pro Asn Ile Asp Lys Lys
                 770                 775                 780

 Glu Glu Asp Leu Glu Asp Lys Asn Asn Phe Gly Ala Glu Pro Pro
                 785                 790                 795

 His Gln Asn Gly Glu Cys Tyr Pro Asn Glu Lys Asn Ser Val Asn
                 800                 805                 810

 Met Asp Leu Asp


<210> 6335
<211> 2470
<212> DNA
<213> Homo sapien

<400> 6335
 ttggcgggcg gaagcggcca caacccggcg atcgaaaaga ttcttaggaa 50

 cgccgtacca gccgcgtctc tcaggacagc aggcccctgt ccttctgtcg 100

 ggcgccgctc agccgtgccc tccgcccctc aggttctttt tctaattcca 150

 aataaacttg caagaggact atgaaagatt atgatgaact tctcaaatat 200

 tatgaattac atgaaactat tgggacaggt ggctttgcaa aggtcaaact 250

 tgcctgccat atccttactg gagagatggt agctataaaa atcatggata 300

 aaaacacact agggagtgat ttgccccgga tcaaaacgga gattgaggcc 350

 ttgaagaacc tgagacatca gcatatatgt caactctacc atgtgctaga 400

 gacagccaac aaaatattca tggttcttga gtactgccct ggaggagagc 450

 tgtttgacta tataatttcc caggatcgcc tgtcagaaga ggagacccgg 500

 gttgtcttcc gtcagatagt atctgctgtt gcttatgtgc acagccaggg 550

 ctatgctcac agggacctca agccagaaaa tttgctgttt gatgaatatc 600

 ataaattaaa gctgattgac tttggtctct gtgcaaaacc caagggtaac 650

 aaggattacc atctacagac atgctgtggg agtctggctt atgcagcacc 700

 tgagttaata caaggcaaat catatcttgg atcagaggca gatgtttgga 750

 gcatgggcat actgttatat gttcttatgt gtggatttct accatttgat 800

 gatgataatg taatggcttt atacaagaag attatgagag gaaaatatga 850

 tgttcccaag tggctctctc ccagtagcat tctgcttctt caacaaatgc 900

 tgcaggtgga cccaaagaaa cggatttcta tgaaaaatct attgaaccat 950

 ccctggatca tgcaagatta caactatcct gttgagtggc aaagcaagaa 1000

 tccttttatt cacctcgatg atgattgcgt aacagaactt tctgtacatc 1050

 acagaaacaa caggcaaaca atggaggatt taatttcact gtggcagtat 1100

 gatcacctca cggctaccta tcttctgctt ctagccaaga aggctcgggg 1150

 aaaaccagtt cgtttaaggc tttcttcttt ctcctgtgga caagccagtg 1200

 ctaccccatt cacagacatc aagtcaaata attggagtct ggaagatgtg 1250

 accgcaagtg ataaaaatta tgtggcggga ttaatagact atgattggtg 1300

 tgaagatgat ttatcaacag gtgctgctac tccccgaaca tcacagttta 1350

 ccaagtactg gacagaatca aatggggtgg aatctaaatc attaactcca 1400

 gccttatgca gaacacctgc aaataaatta aagaacaaag aaaatgtata 1450

 tactcctaag tctgctgtaa agaatgaaga gtactttatg tttcctgagc 1500

 caaagactcc agttaataag aaccagcata agagagaaat actcactacg 1550

 ccaaatcgtt acactacacc ctcaaaagct agaaaccagt gcctgaaaga 1600

 aactccaatt aaaataccag taaattcaac aggaacagac aagttaatga 1650

 caggtgtcat tagccctgag aggcggtgcc gctcagtgga attggatctc 1700

 aaccaagcac atatggagga gactccaaaa agaaagggag ccaaagtgtt 1750

 tgggagcctt gaaagggggt tggataaggt tatcactgtg ctcaccagga 1800

 gcaaaaggaa gggttctgcc agagacgggc ccagaagact aaagcttcac 1850

 tataatgtga ctacaactag attagtgaat ccagatcaac tgttgaatga 1900

 aataatgtct attcttccaa agaagcatgt tgactttgta caaaagggtt 1950

 atacactgaa gtgtcaaaca cagtcagatt ttgggaaagt gacaatgcaa 2000

 tttgaattag aagtgtgcca gcttcaaaaa cccgatgtgg tgggtatcag 2050

 gaggcagcgg cttaagggcg atgcctgggt ttacaaaaga ttagtggaag 2100

 acatcctatc tagctgcaag gtataattga tggattcttc catcctgccg 2150

 gatgagtgtg ggtgtgatac agcctacata aagactgtta tgatcgcttt 2200

 gattttaaag ttcattggaa ctaccaactt gtttctaaag agctatctta 2250

 agaccaatat ctctttgttt ttaaacaaaa gatattattt tgtgtatgaa 2300

 tctaaatcaa gcccatctgt cattatgtta ctgtcttttt taatcatgtg 2350

 gttttgtata ttaataattg ttgactttct tagattcact tccatatgtg 2400

 aatgtaagct cttaactatg tctctttgta atgtgtaatt tctttctgaa 2450

 ataaaaccat ttgtgaatat 2470

<210> 6336
<211> 651
<212> PRT
<213> Homo sapien

<400> 6336
 Met Lys Asp Tyr Asp Glu Leu Leu Lys Tyr Tyr Glu Leu His Glu
   1               5                  10                  15

 Thr Ile Gly Thr Gly Gly Phe Ala Lys Val Lys Leu Ala Cys His
                  20                  25                  30

 Ile Leu Thr Gly Glu Met Val Ala Ile Lys Ile Met Asp Lys Asn
                  35                  40                  45

 Thr Leu Gly Ser Asp Leu Pro Arg Ile Lys Thr Glu Ile Glu Ala
                  50                  55                  60

 Leu Lys Asn Leu Arg His Gln His Ile Cys Gln Leu Tyr His Val
                  65                  70                  75

 Leu Glu Thr Ala Asn Lys Ile Phe Met Val Leu Glu Tyr Cys Pro
                  80                  85                  90

 Gly Gly Glu Leu Phe Asp Tyr Ile Ile Ser Gln Asp Arg Leu Ser
                  95                 100                 105

 Glu Glu Glu Thr Arg Val Val Phe Arg Gln Ile Val Ser Ala Val
                 110                 115                 120

 Ala Tyr Val His Ser Gln Gly Tyr Ala His Arg Asp Leu Lys Pro
                 125                 130                 135

 Glu Asn Leu Leu Phe Asp Glu Tyr His Lys Leu Lys Leu Ile Asp
                 140                 145                 150

 Phe Gly Leu Cys Ala Lys Pro Lys Gly Asn Lys Asp Tyr His Leu
                 155                 160                 165

 Gln Thr Cys Cys Gly Ser Leu Ala Tyr Ala Ala Pro Glu Leu Ile
                 170                 175                 180

 Gln Gly Lys Ser Tyr Leu Gly Ser Glu Ala Asp Val Trp Ser Met
                 185                 190                 195

 Gly Ile Leu Leu Tyr Val Leu Met Cys Gly Phe Leu Pro Phe Asp
                 200                 205                 210

 Asp Asp Asn Val Met Ala Leu Tyr Lys Lys Ile Met Arg Gly Lys
                 215                 220                 225

 Tyr Asp Val Pro Lys Trp Leu Ser Pro Ser Ser Ile Leu Leu Leu
                 230                 235                 240

 Gln Gln Met Leu Gln Val Asp Pro Lys Lys Arg Ile Ser Met Lys
                 245                 250                 255

 Asn Leu Leu Asn His Pro Trp Ile Met Gln Asp Tyr Asn Tyr Pro
                 260                 265                 270

 Val Glu Trp Gln Ser Lys Asn Pro Phe Ile His Leu Asp Asp Asp
                 275                 280                 285

 Cys Val Thr Glu Leu Ser Val His His Arg Asn Asn Arg Gln Thr
                 290                 295                 300

 Met Glu Asp Leu Ile Ser Leu Trp Gln Tyr Asp His Leu Thr Ala
                 305                 310                 315

 Thr Tyr Leu Leu Leu Leu Ala Lys Lys Ala Arg Gly Lys Pro Val
                 320                 325                 330

 Arg Leu Arg Leu Ser Ser Phe Ser Cys Gly Gln Ala Ser Ala Thr
                 335                 340                 345

 Pro Phe Thr Asp Ile Lys Ser Asn Asn Trp Ser Leu Glu Asp Val
                 350                 355                 360

 Thr Ala Ser Asp Lys Asn Tyr Val Ala Gly Leu Ile Asp Tyr Asp
                 365                 370                 375

 Trp Cys Glu Asp Asp Leu Ser Thr Gly Ala Ala Thr Pro Arg Thr
                 380                 385                 390

 Ser Gln Phe Thr Lys Tyr Trp Thr Glu Ser Asn Gly Val Glu Ser
                 395                 400                 405

 Lys Ser Leu Thr Pro Ala Leu Cys Arg Thr Pro Ala Asn Lys Leu
                 410                 415                 420

 Lys Asn Lys Glu Asn Val Tyr Thr Pro Lys Ser Ala Val Lys Asn
                 425                 430                 435

 Glu Glu Tyr Phe Met Phe Pro Glu Pro Lys Thr Pro Val Asn Lys
                 440                 445                 450

 Asn Gln His Lys Arg Glu Ile Leu Thr Thr Pro Asn Arg Tyr Thr
                 455                 460                 465

 Thr Pro Ser Lys Ala Arg Asn Gln Cys Leu Lys Glu Thr Pro Ile
                 470                 475                 480

 Lys Ile Pro Val Asn Ser Thr Gly Thr Asp Lys Leu Met Thr Gly
                 485                 490                 495

 Val Ile Ser Pro Glu Arg Arg Cys Arg Ser Val Glu Leu Asp Leu
                 500                 505                 510

 Asn Gln Ala His Met Glu Glu Thr Pro Lys Arg Lys Gly Ala Lys
                 515                 520                 525

 Val Phe Gly Ser Leu Glu Arg Gly Leu Asp Lys Val Ile Thr Val
                 530                 535                 540

 Leu Thr Arg Ser Lys Arg Lys Gly Ser Ala Arg Asp Gly Pro Arg
                 545                 550                 555

 Arg Leu Lys Leu His Tyr Asn Val Thr Thr Thr Arg Leu Val Asn
                 560                 565                 570

 Pro Asp Gln Leu Leu Asn Glu Ile Met Ser Ile Leu Pro Lys Lys
                 575                 580                 585

 His Val Asp Phe Val Gln Lys Gly Tyr Thr Leu Lys Cys Gln Thr
                 590                 595                 600

 Gln Ser Asp Phe Gly Lys Val Thr Met Gln Phe Glu Leu Glu Val
                 605                 610                 615

 Cys Gln Leu Gln Lys Pro Asp Val Val Gly Ile Arg Arg Gln Arg
                 620                 625                 630

 Leu Lys Gly Asp Ala Trp Val Tyr Lys Arg Leu Val Glu Asp Ile
                 635                 640                 645

 Leu Ser Ser Cys Lys Val
                 650

<210> 6337
<211> 2912
<212> DNA
<213> Homo sapien

<400> 6337
 cagttgcttc agcgtcccgg tgtggctgtg ccgttggtcc tgtgcggtca 50

 cttagccaag atgcctgagg aaacccagac ccaagaccaa ccgatggagg 100

 aggaggaggt tgagacgttc gcctttcagg cagaaattgc ccagttgatg 150

 tcattgatca tcaatacttt ctactcgaac aaagagatct ttctgagaga 200

 gctcatttca aattcatcag atgcattgga caaaatccgg tatgaaactt 250

 tgacagatcc cagtaaatta gactctggga aagagctgca tattaacctt 300

 ataccgaaca aacaagatcg aactctcact attgtggata ctggaattgg 350

 aatgaccaag gctgacttga tcaataacct tggtactatc gccaagtctg 400

 ggaccaaagc gttcatggaa gctttgcagg ctggtgcaga tatctctatg 450

 attggccagt tcggtgttgg tttttattct gcttatttgg ttgctgagaa 500

 agtaactgtg atcaccaaac ataacgatga tgagcagtac gcttgggagt 550

 cctcagcagg gggatcattc acagtgagga cagacacagg tgaacctatg 600

 ggtcgtggaa caaaagttat cctacacctg aaagaagacc aaactgagta 650

 cttggaggaa cgaagaataa aggagattgt gaagaaacat tctcagttta 700

 ttggatatcc cattactctt tttgtggaga aggaacgtga taaagaagta 750

 agcgatgatg aggctgaaga aaaggaagac aaagaagaag aaaaagaaaa 800

 agaagagaaa gagtcggaag acaaacctga aattgaagat gttggttctg 850

 atgaggaaga agaaaagaag gatggtgaca agaagaagaa gaagaagatt 900

 aaggaaaagt acatcgatca agaagagctc aacaaaacaa agcccatctg 950

 gaccagaaat cccgacgata ttactaatga ggagtacgga gaattctata 1000

 agagcttgac caatgactgg gaagatcact tggcagtgaa gcatttttca 1050

 gttgaaggac agttggaatt cagagccctt ctatttgtcc cacgacgtgc 1100

 tccttttgat ctgtttgaaa acagaaagaa aaagaacaat atcaaattgt 1150

 atgtacgcag agttttcatc atggataact gtgaggagct aatccctgaa 1200

 tatctgaact tcattagagg ggtggtagac tcggaggatc tccctctaaa 1250

 catatcccgt gagatgttgc aacaaagcaa aattttgaaa gttatcagga 1300

 agaatttggt caaaaaatgc ttagaactct ttactgaact ggcggaagat 1350

 aaagagaact acaagaaatt ctatgagcag ttctctaaaa acataaagct 1400

 tggaatacac gaagactctc aaaatcggaa gaagctttca gagctgttaa 1450

 ggtactacac atctgcctct ggtgatgaga tggtttctct caaggactac 1500

 tgcaccagaa tgaaggagaa ccagaaacat atctattata tcacaggtga 1550

 gaccaaggac caggtagcta actcagcctt tgtggaacgt cttcggaaac 1600

 atggcttaga agtgatctat atgattgagc ccattgatga gtactgtgtc 1650

 caacagctga aggaatttga ggggaagact ttagtgtcag tcaccaaaga 1700

 aggcctggaa cttccagagg atgaagaaga gaaaaagaag caggaagaga 1750

 aaaaaacaaa gtttgagaac ctctgcaaaa tcatgaaaga catattggag 1800

 aaaaaagttg aaaaggtggt tgtgtcaaac cgattggtga catctccatg 1850

 ctgtattgtc acaagcacat atggctggac agcaaacatg gagagaatca 1900

 tgaaagctca agccctaaga gacaactcaa caatgggtta catggcagca 1950

 aagaaacacc tggagataaa ccctgaccat tccattattg agaccttaag 2000

 gcaaaaggca gaggctgata agaacgacaa gtctgtgaag gatctggtca 2050

 tcttgcttta tgaaactgcg ctcctgtctt ctggcttcag tctggaagat 2100

 ccccagacac atgctaacag gatctacagg atgatcaaac ttggtctggg 2150

 tattgatgaa gatgacccta ctgctgatga taccagtgct gctgtaactg 2200

 aagaaatgcc accccttgaa ggagatgacg acacatcacg catggaagaa 2250

 gtagactaat ctctggctga gggatgactt acctgttcag tactctacaa 2300

 ttcctctgat aatatatttt caaggatgtt tttctttatt tttgttaata 2350

 ttaaaaagtc tgtatggcat gacaactact ttaaggggaa gataagattt 2400

 ctgtctacta agtgatgctg tgatacctta ggcactaaag cagagctagt 2450

 aatgcttttt gagtttcatg ttggttcttt cacagatggg gtaacgtgca 2500

 ctgtaagacg tatgtaacat gatgttaact ttgtgtggtc taaagtgttt 2550

 agctgtcaag ccggatgcct aagtagacca aatcttgtta ttgaagtgtt 2600

 ctgagctgta tcttgatgtt tagaaaagta ttcgttacat cttgtaggat 2650

 ctactttttg aacttttcat tccctgtagt tgacaattct gcatgtacta 2700

 gtcctctaga aataggttaa actgaagcaa cttgatggaa ggatctctcc 2750

 acagggcttg ttttccaaag aaaagtattg tttggaggag caaagttaaa 2800

 agcctaccta agcatatcgt aaagctgttc aaatactcga gcccagtctt 2850

 gtggatggaa atgtagtgct cgagtcacat tctgcttaaa gttgtaacaa 2900

 atacagatga gt 2912

<210> 6338
<211> 732
<212> PRT
<213> Homo sapien

<400> 6338
 Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu
   1               5                  10                  15

 Glu Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met
                  20                  25                  30

 Ser Leu Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu
                  35                  40                  45

 Arg Glu Leu Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Arg
                  50                  55                  60

 Tyr Glu Thr Leu Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu
                  65                  70                  75

 Leu His Ile Asn Leu Ile Pro Asn Lys Gln Asp Arg Thr Leu Thr
                  80                  85                  90

 Ile Val Asp Thr Gly Ile Gly Met Thr Lys Ala Asp Leu Ile Asn
                  95                 100                 105

 Asn Leu Gly Thr Ile Ala Lys Ser Gly Thr Lys Ala Phe Met Glu
                 110                 115                 120

 Ala Leu Gln Ala Gly Ala Asp Ile Ser Met Ile Gly Gln Phe Gly
                 125                 130                 135

 Val Gly Phe Tyr Ser Ala Tyr Leu Val Ala Glu Lys Val Thr Val
                 140                 145                 150

 Ile Thr Lys His Asn Asp Asp Glu Gln Tyr Ala Trp Glu Ser Ser
                 155                 160                 165

 Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Thr Gly Glu Pro Met
                 170                 175                 180

 Gly Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu Asp Gln Thr
                 185                 190                 195

 Glu Tyr Leu Glu Glu Arg Arg Ile Lys Glu Ile Val Lys Lys His
                 200                 205                 210

 Ser Gln Phe Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys Glu
                 215                 220                 225

 Arg Asp Lys Glu Val Ser Asp Asp Glu Ala Glu Glu Lys Glu Asp
                 230                 235                 240

 Lys Glu Glu Glu Lys Glu Lys Glu Glu Lys Glu Ser Glu Asp Lys
                 245                 250                 255

 Pro Glu Ile Glu Asp Val Gly Ser Asp Glu Glu Glu Glu Lys Lys
                 260                 265                 270

 Asp Gly Asp Lys Lys Lys Lys Lys Lys Ile Lys Glu Lys Tyr Ile
                 275                 280                 285

 Asp Gln Glu Glu Leu Asn Lys Thr Lys Pro Ile Trp Thr Arg Asn
                 290                 295                 300

 Pro Asp Asp Ile Thr Asn Glu Glu Tyr Gly Glu Phe Tyr Lys Ser
                 305                 310                 315

 Leu Thr Asn Asp Trp Glu Asp His Leu Ala Val Lys His Phe Ser
                 320                 325                 330

 Val Glu Gly Gln Leu Glu Phe Arg Ala Leu Leu Phe Val Pro Arg
                 335                 340                 345

 Arg Ala Pro Phe Asp Leu Phe Glu Asn Arg Lys Lys Lys Asn Asn
                 350                 355                 360

 Ile Lys Leu Tyr Val Arg Arg Val Phe Ile Met Asp Asn Cys Glu
                 365                 370                 375

 Glu Leu Ile Pro Glu Tyr Leu Asn Phe Ile Arg Gly Val Val Asp
                 380                 385                 390

 Ser Glu Asp Leu Pro Leu Asn Ile Ser Arg Glu Met Leu Gln Gln
                 395                 400                 405

 Ser Lys Ile Leu Lys Val Ile Arg Lys Asn Leu Val Lys Lys Cys
                 410                 415                 420

 Leu Glu Leu Phe Thr Glu Leu Ala Glu Asp Lys Glu Asn Tyr Lys
                 425                 430                 435

 Lys Phe Tyr Glu Gln Phe Ser Lys Asn Ile Lys Leu Gly Ile His
                 440                 445                 450

 Glu Asp Ser Gln Asn Arg Lys Lys Leu Ser Glu Leu Leu Arg Tyr
                 455                 460                 465

 Tyr Thr Ser Ala Ser Gly Asp Glu Met Val Ser Leu Lys Asp Tyr
                 470                 475                 480

 Cys Thr Arg Met Lys Glu Asn Gln Lys His Ile Tyr Tyr Ile Thr
                 485                 490                 495

 Gly Glu Thr Lys Asp Gln Val Ala Asn Ser Ala Phe Val Glu Arg
                 500                 505                 510

 Leu Arg Lys His Gly Leu Glu Val Ile Tyr Met Ile Glu Pro Ile
                 515                 520                 525

 Asp Glu Tyr Cys Val Gln Gln Leu Lys Glu Phe Glu Gly Lys Thr
                 530                 535                 540

 Leu Val Ser Val Thr Lys Glu Gly Leu Glu Leu Pro Glu Asp Glu
                 545                 550                 555

 Glu Glu Lys Lys Lys Gln Glu Glu Lys Lys Thr Lys Phe Glu Asn
                 560                 565                 570

 Leu Cys Lys Ile Met Lys Asp Ile Leu Glu Lys Lys Val Glu Lys
                 575                 580                 585

 Val Val Val Ser Asn Arg Leu Val Thr Ser Pro Cys Cys Ile Val
                 590                 595                 600

 Thr Ser Thr Tyr Gly Trp Thr Ala Asn Met Glu Arg Ile Met Lys
                 605                 610                 615

 Ala Gln Ala Leu Arg Asp Asn Ser Thr Met Gly Tyr Met Ala Ala
                 620                 625                 630

 Lys Lys His Leu Glu Ile Asn Pro Asp His Ser Ile Ile Glu Thr
                 635                 640                 645

 Leu Arg Gln Lys Ala Glu Ala Asp Lys Asn Asp Lys Ser Val Lys
                 650                 655                 660

 Asp Leu Val Ile Leu Leu Tyr Glu Thr Ala Leu Leu Ser Ser Gly
                 665                 670                 675

 Phe Ser Leu Glu Asp Pro Gln Thr His Ala Asn Arg Ile Tyr Arg
                 680                 685                 690

 Met Ile Lys Leu Gly Leu Gly Ile Asp Glu Asp Asp Pro Thr Ala
                 695                 700                 705

 Asp Asp Thr Ser Ala Ala Val Thr Glu Glu Met Pro Pro Leu Glu
                 710                 715                 720

 Gly Asp Asp Asp Thr Ser Arg Met Glu Glu Val Asp
                 725                 730

<210> 6339
<211> 1438
<212> DNA
<213> Homo sapien

<400> 6339
 cggtaactac cccggctgcg cacagctcgg cgctccttcc cgctccctca 50

 cacaccgcct cagcccgcac cggcagtaga agatggtgaa agaaacaact 100

 tactacgatg ttttgggggt caaacccaat gctactcagg aagaattgaa 150

 aaaggcttat aggaaactgg ccttgaagta ccatcctgat aagaacccaa 200

 atgaaggaga gaagtttaaa cagatttctc aagcttacga agttctctct 250

 gatgcaaaga aaagggaatt atatgacaaa ggaggagaac aggcaattaa 300

 agagggtgga gcaggtggcg gttttggctc ccccatggac atctttgata 350

 tgttttttgg aggaggagga aggatgcaga gagaaaggag aggtaaaaat 400

 gttgtacatc agctctcagt aaccctagaa gacttatata atggtgcaac 450

 aagaaaactg gctctgcaaa agaatgtgat ttgtgacaaa tgtgaaggta 500

 gaggaggtaa gaaaggagca gtagagtgct gtcccaattg ccgaggtact 550

 ggaatgcaaa taagaattca tcagatagga cctggaatgg ttcagcaaat 600

 tcagtctgtg tgcatggagt gccagggcca tggggagcgg atcagtccta 650

 aagatagatg taaaagctgc aacggaagga agatagttcg agagaagaaa 700

 attttagaag ttcatattga caaaggcatg aaagatggcc agaagataac 750

 attccatggt gaaggagacc aagaaccagg actggagcca ggcgatatta 800

 tcattgtgtt agatcagaag gaccatgctg tttttactcg acgaggagaa 850

 gaccttttca tgtgtatgga catacagctc gttgaagcac tgtgtggctt 900

 ccagaagcca atatctactc ttgacaaccg aaccatcgtc atcacctctc 950

 atccaggtca gattgtcaag catggagata tcaagtgtgt actaaatgaa 1000

 ggcatgccaa tttatcgtag accatatgaa aagggtcgcc taatcatcga 1050

 atttaaggta aactttcctg agaatggctt tctctctcct gataaactgt 1100

 ctttgctgga aaaactccta cccgagagga aggaagtgga agagactgat 1150

 gagatggacc aagtagaact ggtggacttt gatccaaatc aggaaagacg 1200

 gcgccactac aatggagaag catatgagga tgatgaacat catcccagag 1250

 gtggtgttca gtgtcagacc tcttaatggc cagtgaataa cactcactgc 1300

 tggcatttaa tgtgcagtag tgaatgagtg aaggactgta atcataatat 1350

 gctcactact tgctcttgtt tttgttttaa taaactatag tagtgttata 1400

 aaaagttaaa tgaagaataa acgcaaatat aaaagctc 1438

<210> 6340
<211> 397
<212> PRT
<213> Homo sapien

<400> 6340
 Met Val Lys Glu Thr Thr Tyr Tyr Asp Val Leu Gly Val Lys Pro
   1               5                  10                  15

 Asn Ala Thr Gln Glu Glu Leu Lys Lys Ala Tyr Arg Lys Leu Ala
                  20                  25                  30

 Leu Lys Tyr His Pro Asp Lys Asn Pro Asn Glu Gly Glu Lys Phe
                  35                  40                  45

 Lys Gln Ile Ser Gln Ala Tyr Glu Val Leu Ser Asp Ala Lys Lys
                  50                  55                  60

 Arg Glu Leu Tyr Asp Lys Gly Gly Glu Gln Ala Ile Lys Glu Gly
                  65                  70                  75

 Gly Ala Gly Gly Gly Phe Gly Ser Pro Met Asp Ile Phe Asp Met
                  80                  85                  90

 Phe Phe Gly Gly Gly Gly Arg Met Gln Arg Glu Arg Arg Gly Lys
                  95                 100                 105

 Asn Val Val His Gln Leu Ser Val Thr Leu Glu Asp Leu Tyr Asn
                 110                 115                 120

 Gly Ala Thr Arg Lys Leu Ala Leu Gln Lys Asn Val Ile Cys Asp
                 125                 130                 135

 Lys Cys Glu Gly Arg Gly Gly Lys Lys Gly Ala Val Glu Cys Cys
                 140                 145                 150

 Pro Asn Cys Arg Gly Thr Gly Met Gln Ile Arg Ile His Gln Ile
                 155                 160                 165

 Gly Pro Gly Met Val Gln Gln Ile Gln Ser Val Cys Met Glu Cys
                 170                 175                 180

 Gln Gly His Gly Glu Arg Ile Ser Pro Lys Asp Arg Cys Lys Ser
                 185                 190                 195

 Cys Asn Gly Arg Lys Ile Val Arg Glu Lys Lys Ile Leu Glu Val
                 200                 205                 210

 His Ile Asp Lys Gly Met Lys Asp Gly Gln Lys Ile Thr Phe His
                 215                 220                 225

 Gly Glu Gly Asp Gln Glu Pro Gly Leu Glu Pro Gly Asp Ile Ile
                 230                 235                 240

 Ile Val Leu Asp Gln Lys Asp His Ala Val Phe Thr Arg Arg Gly
                 245                 250                 255

 Glu Asp Leu Phe Met Cys Met Asp Ile Gln Leu Val Glu Ala Leu
                 260                 265                 270

 Cys Gly Phe Gln Lys Pro Ile Ser Thr Leu Asp Asn Arg Thr Ile
                 275                 280                 285

 Val Ile Thr Ser His Pro Gly Gln Ile Val Lys His Gly Asp Ile
                 290                 295                 300

 Lys Cys Val Leu Asn Glu Gly Met Pro Ile Tyr Arg Arg Pro Tyr
                 305                 310                 315

 Glu Lys Gly Arg Leu Ile Ile Glu Phe Lys Val Asn Phe Pro Glu
                 320                 325                 330

 Asn Gly Phe Leu Ser Pro Asp Lys Leu Ser Leu Leu Glu Lys Leu
                 335                 340                 345

 Leu Pro Glu Arg Lys Glu Val Glu Glu Thr Asp Glu Met Asp Gln
                 350                 355                 360

 Val Glu Leu Val Asp Phe Asp Pro Asn Gln Glu Arg Arg Arg His
                 365                 370                 375

 Tyr Asn Gly Glu Ala Tyr Glu Asp Asp Glu His His Pro Arg Gly
                 380                 385                 390

 Gly Val Gln Cys Gln Thr Ser
                 395

<210> 6341
<211> 2156
<212> DNA
<213> Homo sapien

<400> 6341
 cccggcctcc cgcacgcccc gcaggtagcg cccccgcccg cggcccagag 50

 tgcgctcgcg ccggcaccag ctcccggata aacggcgcgc cgcgcggaga 100

 tgacagccga ggagatgaag gcgaccgaga gcggggcgca gtcggcgccg 150

 ctgcccatgg agggagtgga catcagcccc aaacaggacg aaggcgtgct 200

 gaaggtcatc aagagagagg gcacaggtac agagatgccc atgattgggg 250

 accgagtctt tgtccactac actggctggc tattagatgg cacaaagttt 300

 gactccagtc tggatcgcaa ggacaaattc tcctttgacc tgggaaaagg 350

 ggaggtcatc aaggcttggg acattgccat agccaccatg aaggtggggg 400

 aggtgtgcca catcacctgc aaaccagaat atgcctacgg ttcagcaggc 450

 agtcctccaa agattccccc caatgccacg cttgtatttg aggtggagtt 500

 gtttgagttt aagggagaag atctgacgga agaggaagat ggcggaatca 550

 ttcgcagaat acagactcgc ggtgaaggct atgctaagcc caatgagggt 600

 gctatcgtgg aggttgcact ggaagggtac tacaaggaca agctctttga 650

 ccagcgggag ctccgctttg agattggcga gggggagaac ctggatctgc 700

 cttatggtct ggagagggcc attcagcgca tggagaaagg agaacattcc 750

 atcgtgtacc tcaagcccag ctatgctttt ggcagtgttg ggaaggaaaa 800

 gttccaaatc ccaccaaatg ctgagctgaa atatgaatta cacctcaaga 850

 gttttgaaaa ggccaaggag tcttgggaga tgaattcaga agagaagctg 900

 gaacagagca ccatagtgaa agagcggggc actgtgtact tcaaggaagg 950

 taaatacaag caagctttac tacagtataa gaagatcgtg tcttggctgg 1000

 aatatgagtc tagtttttcc aatgaggaag cacagaaagc acaggccctt 1050

 cgactggcct ctcacctcaa cctggccatg tgtcatctga aactacaggc 1100

 cttctctgct gccattgaaa gctgtaacaa ggccctagaa ctggacagca 1150

 acaacgagaa gggcctcttc cgccggggag aggcccacct ggccgtgaat 1200

 gactttgaac tggcacgggc tgatttccag aaggtcctgc agctctaccc 1250

 caacaacaaa gccgccaaga cccagctggc tgtgtgccag cagcggatcc 1300

 gaaggcagct tgcccgggag aagaagctct atgccaatat gtttgagagg 1350

 ctggctgagg aggagaacaa ggccaaggca gaggcttcct caggagacca 1400

 tcccactgac acagagatga aggaggagca gaagagcaac acggcaggga 1450

 gccagtctca ggtggagaca gaagcatagc ccctctccac cagccctact 1500

 cctgcggctg cctgcccccc agtctcccca ctccaccctg ttagttttgt 1550

 aaaaactgaa gaattttgag tgaattagac ctttattttt ctatctggtt 1600

 ggatggtggc tttaggggaa gggggaaagg tgtaggctgg gggattgagg 1650

 tggggaatca ttttagctgg tgtcagcccc tcttcccttc ctccattgca 1700

 catgaacata tgtccatcca tatatattca tcagaatgtt aatttatttt 1750

 gctccctctg ttaggtccat tttctaaggg tagaagaggc aagtggtagg 1800

 gatgaggtct gataagaacc cagggtggag agggagactc ctgggcagcc 1850

 gttttcctca tcctttccct ctcccagtcc atttccaaat gtggcctcca 1900

 tgtgggtgct agggacatgg gaaaaaccac tgctatgcca tttcttctct 1950

 ctgttccctt cctcaccccc gacggtgtgg ctgatgatgt cttctggtgt 2000

 catggtgacc accccctgtt ccctgttctg gtatttcccc tgtcagtttc 2050

 ccctctcggc caggttgtgt cccaaaatcc cctcagcctc ttctctgcac 2100

 gttgctgaag gtccaggctt gcctcaagtt ccatgcttga gcaataaagt 2150

 ggaaac 2156

<210> 6342
<211> 459
<212> PRT
<213> Homo sapien

<400> 6342
 Met Thr Ala Glu Glu Met Lys Ala Thr Glu Ser Gly Ala Gln Ser
   1               5                  10                  15

 Ala Pro Leu Pro Met Glu Gly Val Asp Ile Ser Pro Lys Gln Asp
                  20                  25                  30

 Glu Gly Val Leu Lys Val Ile Lys Arg Glu Gly Thr Gly Thr Glu
                  35                  40                  45

 Met Pro Met Ile Gly Asp Arg Val Phe Val His Tyr Thr Gly Trp
                  50                  55                  60

 Leu Leu Asp Gly Thr Lys Phe Asp Ser Ser Leu Asp Arg Lys Asp
                  65                  70                  75

 Lys Phe Ser Phe Asp Leu Gly Lys Gly Glu Val Ile Lys Ala Trp
                  80                  85                  90

 Asp Ile Ala Ile Ala Thr Met Lys Val Gly Glu Val Cys His Ile
                  95                 100                 105

 Thr Cys Lys Pro Glu Tyr Ala Tyr Gly Ser Ala Gly Ser Pro Pro
                 110                 115                 120

 Lys Ile Pro Pro Asn Ala Thr Leu Val Phe Glu Val Glu Leu Phe
                 125                 130                 135

 Glu Phe Lys Gly Glu Asp Leu Thr Glu Glu Glu Asp Gly Gly Ile
                 140                 145                 150

 Ile Arg Arg Ile Gln Thr Arg Gly Glu Gly Tyr Ala Lys Pro Asn
                 155                 160                 165

 Glu Gly Ala Ile Val Glu Val Ala Leu Glu Gly Tyr Tyr Lys Asp
                 170                 175                 180

 Lys Leu Phe Asp Gln Arg Glu Leu Arg Phe Glu Ile Gly Glu Gly
                 185                 190                 195

 Glu Asn Leu Asp Leu Pro Tyr Gly Leu Glu Arg Ala Ile Gln Arg
                 200                 205                 210

 Met Glu Lys Gly Glu His Ser Ile Val Tyr Leu Lys Pro Ser Tyr
                 215                 220                 225

 Ala Phe Gly Ser Val Gly Lys Glu Lys Phe Gln Ile Pro Pro Asn
                 230                 235                 240

 Ala Glu Leu Lys Tyr Glu Leu His Leu Lys Ser Phe Glu Lys Ala
                 245                 250                 255

 Lys Glu Ser Trp Glu Met Asn Ser Glu Glu Lys Leu Glu Gln Ser
                 260                 265                 270

 Thr Ile Val Lys Glu Arg Gly Thr Val Tyr Phe Lys Glu Gly Lys
                 275                 280                 285

 Tyr Lys Gln Ala Leu Leu Gln Tyr Lys Lys Ile Val Ser Trp Leu
                 290                 295                 300

 Glu Tyr Glu Ser Ser Phe Ser Asn Glu Glu Ala Gln Lys Ala Gln
                 305                 310                 315

 Ala Leu Arg Leu Ala Ser His Leu Asn Leu Ala Met Cys His Leu
                 320                 325                 330

 Lys Leu Gln Ala Phe Ser Ala Ala Ile Glu Ser Cys Asn Lys Ala
                 335                 340                 345

 Leu Glu Leu Asp Ser Asn Asn Glu Lys Gly Leu Phe Arg Arg Gly
                 350                 355                 360

 Glu Ala His Leu Ala Val Asn Asp Phe Glu Leu Ala Arg Ala Asp
                 365                 370                 375

 Phe Gln Lys Val Leu Gln Leu Tyr Pro Asn Asn Lys Ala Ala Lys
                 380                 385                 390

 Thr Gln Leu Ala Val Cys Gln Gln Arg Ile Arg Arg Gln Leu Ala
                 395                 400                 405

 Arg Glu Lys Lys Leu Tyr Ala Asn Met Phe Glu Arg Leu Ala Glu
                 410                 415                 420

 Glu Glu Asn Lys Ala Lys Ala Glu Ala Ser Ser Gly Asp His Pro
                 425                 430                 435

 Thr Asp Thr Glu Met Lys Glu Glu Gln Lys Ser Asn Thr Ala Gly
                 440                 445                 450

 Ser Gln Ser Gln Val Glu Thr Glu Ala
                 455

<210> 6343
<211> 1763
<212> DNA
<213> Homo sapien

<400> 6343
 tagctggatt ccagccattg ctgcagctgc tccacagccc ttttcaggac 50

 ccaaacaacc gcagccgctg ttcccaggat ggtgatccgt gtatatattg 100

 catcttcctc tggctctaca gcgattaaga agaaacaaca agatgtgctt 150

 ggtttcctag aagccaacaa aataggattt gaagaaaaag atattgcagc 200

 caatgaagag aatcggaagt ggatgagaga aaatgtacct gaaaatagtc 250

 gaccagccac aggttacccc ctgccacctc agattttcaa tgaaagccag 300

 tatcgcgggg actatgatgc cttctttgaa gccagagaaa ataatgcagt 350

 gtatgccttc ttaggcttga cagccccacc tggttcaaag gaagcagaag 400

 tgcaagcaaa gcagcaagca tgaaccttaa gcactgtgct ttaagcatcc 450

 tgaaaaatga gtctccattg cttttataaa atagcagaat tagctttgct 500

 tcaaaagaaa taggcttaat gttgaaataa tagattagtt gggttttcac 550

 atgcaaacat tcaaaatgaa tacaaaatta aaatttgaac attatggtga 600

 ttatggtgag gagaatggga tattaacata aaattatatt aataagtaga 650

 tatcgtagaa atagtgttgt tacctgccaa gccatcctgt atacaccaat 700

 gattttacaa agaaaacacc cttccctcct tctgccatta ctatggcaac 750

 ttaagtgtat ctgcagctct acattaaaaa ggagaaagag aaataacctg 800

 tctctcattc ctaagttgcc tcattaattt tcatgaacaa gaatatgtac 850

 ctttttgatg ctatattact gcgattaaaa aagttcttgc aggtaatgtt 900

 tatgtatagt taaacgttgt aatttcttat cgtaattata acattcccat 950

 tctttgtaga tgaaactcta catatgaacc acagattttc tgagcttcta 1000

 aatgtagcct ttcattgcac atttcagtga tcagaataga tatcctttta 1050

 cacgcacaaa agcaatagat tcattcagtg gacaagttcc ttgtttaact 1100

 acacagctat gatggaatca tatatccaag ttccttgcct cagtgaaata 1150

 tgcatatgta tatcatgaag tgggatgcca agtaagctta aaatgcattc 1200

 tctagcaaag agattagact tttaaataac tcttataaaa caggttggcg 1250

 atcatttccc aagattggtt tcccttgagt ttttgttaaa acaaatctta 1300

 gtagttttgc ccgtttaaaa caactcacaa tcgtaaatgc tactattcct 1350

 aagatatctt acctttttat ttcagtttag ccatgtattg tatgagtgta 1400

 ttagtctaag cagtgagaat cttttctatg cctctattcc agcaaaaagt 1450

 agaagtatca aataaaaagg gcaactttta aaatattaag cctgaagact 1500

 tctaaaaaga caagaaacat ggcctaaata accaacatag atttacatag 1550

 taagtttcac actaccttat taccaaaagc aaacacctct tactttaaac 1600

 tacattatca tgtatatcta ttgtatgctg gtctttactt tttgccaaaa 1650

 tcaacatata atgaagagat gcctttgttt gatgagattc aaacttgatg 1700

 ctatgcttta aaataaactc agtactttta gaaacataaa aaaaaaaaaa 1750

 aaaaaaaaaa aaa 1763

<210> 6344
<211> 114
<212> PRT
<213> Homo sapien

<400> 6344
 Met Val Ile Arg Val Tyr Ile Ala Ser Ser Ser Gly Ser Thr Ala
   1               5                  10                  15

 Ile Lys Lys Lys Gln Gln Asp Val Leu Gly Phe Leu Glu Ala Asn
                  20                  25                  30

 Lys Ile Gly Phe Glu Glu Lys Asp Ile Ala Ala Asn Glu Glu Asn
                  35                  40                  45

 Arg Lys Trp Met Arg Glu Asn Val Pro Glu Asn Ser Arg Pro Ala
                  50                  55                  60

 Thr Gly Tyr Pro Leu Pro Pro Gln Ile Phe Asn Glu Ser Gln Tyr
                  65                  70                  75

 Arg Gly Asp Tyr Asp Ala Phe Phe Glu Ala Arg Glu Asn Asn Ala
                  80                  85                  90

 Val Tyr Ala Phe Leu Gly Leu Thr Ala Pro Pro Gly Ser Lys Glu
                  95                 100                 105

 Ala Glu Val Gln Ala Lys Gln Gln Ala
                 110

<210> 6345
<211> 1540
<212> DNA
<213> Homo sapien

<400> 6345
 caaaggccag gcctgacgga agagcccagc cttcgccgag ggccgcaggg 50

 agccagagac tcgagcctgc ggttccagcc ccgccgcggt tccggccccg 100

 ccgcgatccc gaggcctgcg catgctcggt gctgcgcggg gctccctcct 150

 taccgcagga gctcctcatc gagaaaccca ggttggtgtc ttttccacgt 200

 ggtagaagct ggctaacctc cacttccaca ttccagccca agggaaagtc 250

 caaggtattg ttgcagcatc tggcagtgag actgaggatg aggacagcat 300

 ggacattccc ttggaccttt cttcatccgc tggctcaggc aagagaagga 350

 gaaggggcaa cctacccaag gagtctgtgc agattcttcg ggattggctg 400

 tatgagcacc gttacaatgc ctatccttca gagcaagaaa aagcgttgct 450

 gtcccagcaa acacacctgt ctacgctaca ggtctgtaac tggttcatca 500

 acgcccgccg caggctcctc cctgacatgc tgagaaagga tggcaaagat 550

 ccaaatcagt tcacaatttc ccgccgtggg gccaagattt ctgaaacgag 600

 ctctgtggag tccgtgatgg gcatcaaaaa cttcatgcca gctctagagg 650

 agaccccatt tcattcctgt acagctgggc caaacccaac cctagggagg 700

 ccactgtctc ctaagccgtc atccccggga tcagttttgg ctcgtccatc 750

 agtgatctgc cataccactg tgactgcatt gaaagatgtc cctttctctc 800

 tctgccagtc ggtcggtgtg ggacaaaaca cagatataca gcagatagcg 850

 gccaaaaact tcacagacac ctctctcatg tacccagagg acacttgtaa 900

 atctggacca agtacgaata cacagagtgg tcttttcaac actcctcccc 950

 ctactccacc ggacctcaac caggacttca gtggatttca gcttctagtg 1000

 gatgttgcac tcaaacgggc tgcagagatg gagcttcagg caaaacttac 1050

 agcttaaccc attttcaagc aaaacagttc tcagaaatgt catgattgcc 1100

 ggggtgaagg caagagatga attgcattat tttatatatt ttttattaat 1150

 atttgcacat gggattgcta aaacagcttc ctgttactga gatgtcttca 1200

 atggaataca gtcattccaa gaactataaa cttaaagcta ctgtagaaac 1250

 aaagggtttt cttttttaaa tgtttcttgg tagattattc ataatgtgag 1300

 atggttccca atatcatgtg attttttttt tcctcccctt cccttttttt 1350

 gttatttttt cagactgtgc aatacttaga gaacctatag catcttctca 1400

 ttcccatgtg gaacaggatg cccacatact gtctaattaa taaattttcc 1450

 attttttttc aaacaagtat gaatctagtt ggttgatgcc ttttttttca 1500

 tgacataata aagtattttc tttaaaaaaa aaaaaaaaaa 1540

<210> 6346
<211> 252
<212> PRT
<213> Homo sapien

<400> 6346
 Met Asp Ile Pro Leu Asp Leu Ser Ser Ser Ala Gly Ser Gly Lys
   1               5                  10                  15

 Arg Arg Arg Arg Gly Asn Leu Pro Lys Glu Ser Val Gln Ile Leu
                  20                  25                  30

 Arg Asp Trp Leu Tyr Glu His Arg Tyr Asn Ala Tyr Pro Ser Glu
                  35                  40                  45

 Gln Glu Lys Ala Leu Leu Ser Gln Gln Thr His Leu Ser Thr Leu
                  50                  55                  60

 Gln Val Cys Asn Trp Phe Ile Asn Ala Arg Arg Arg Leu Leu Pro
                  65                  70                  75

 Asp Met Leu Arg Lys Asp Gly Lys Asp Pro Asn Gln Phe Thr Ile
                  80                  85                  90

 Ser Arg Arg Gly Ala Lys Ile Ser Glu Thr Ser Ser Val Glu Ser
                  95                 100                 105

 Val Met Gly Ile Lys Asn Phe Met Pro Ala Leu Glu Glu Thr Pro
                 110                 115                 120

 Phe His Ser Cys Thr Ala Gly Pro Asn Pro Thr Leu Gly Arg Pro
                 125                 130                 135

 Leu Ser Pro Lys Pro Ser Ser Pro Gly Ser Val Leu Ala Arg Pro
                 140                 145                 150

 Ser Val Ile Cys His Thr Thr Val Thr Ala Leu Lys Asp Val Pro
                 155                 160                 165

 Phe Ser Leu Cys Gln Ser Val Gly Val Gly Gln Asn Thr Asp Ile
                 170                 175                 180

 Gln Gln Ile Ala Ala Lys Asn Phe Thr Asp Thr Ser Leu Met Tyr
                 185                 190                 195

 Pro Glu Asp Thr Cys Lys Ser Gly Pro Ser Thr Asn Thr Gln Ser
                 200                 205                 210

 Gly Leu Phe Asn Thr Pro Pro Pro Thr Pro Pro Asp Leu Asn Gln
                 215                 220                 225

 Asp Phe Ser Gly Phe Gln Leu Leu Val Asp Val Ala Leu Lys Arg
                 230                 235                 240

 Ala Ala Glu Met Glu Leu Gln Ala Lys Leu Thr Ala
                 245                 250

<210> 6347
<211> 1702
<212> DNA
<213> Homo sapien

<400> 6347
 ggagtcgacc gctcgggcag cgcaccgcca cgagagcccg ggacgcggga 50

 aagaccgaaa ggaagaggaa gaggcaccgg tggccatggg gctggaggcg 100

 gcgcgcgagc tggagtgcgc ggcgctgggc acgctgctgc gggatccgcg 150

 ggaggcggaa cgcacgctgc tgctggactg ccgccccttc ctggccttct 200

 gccggcgcca cgtgcgcgcc gcgcggccag tgccttggaa cgcgctgctg 250

 cggcgccgcg cgcgcggccc tcctgccgcc gttctcgcct gcctgctgcc 300

 cgaccgcgcg ctgcggacgc gcctggtccg cggggagctg gcgcgggccg 350

 tggtgctgga cgagggcagt gcctcggtgg cggagctccg gcccgacagc 400

 ccggctcatg tgctgctggc cgcgctgctg cacgagaccc gcgcggggcc 450

 cactgccgtg tacttcctgc gaggaggctt cgacggcttc cagggctgct 500

 gtcccgatct gtgctctgag gcccccgccc ctgcgctgcc gccaacaggg 550

 gacaaaacca gccgctccga ctccagggct cctgtctacg accagggtgg 600

 ccctgtggag atcttgccct acctgttcct gggcagctgc agtcactcgt 650

 cagacctgca ggggctgcag gcctgtggca tcacagccgt cctcaacgtg 700

 tccgccagct gccccaacca ctttgagggc cttttccgct acaagagtat 750

 ccctgtggag gacaaccaga tggtggagat cagtgcctgg ttccaggagg 800

 ccataggctt cattgactgg gtgaagaaca gcggaggccg ggtgctggtg 850

 cactgccagg cgggtatctc gcgctctgcc accatctgtc tggcatacct 900

 catgcagagt cgccgtgtgc ggctggacga ggcctttgac ttcgttaagc 950

 agcgccgggg ggtcatctcc cccaacttca gtttcatggg gcagctgctg 1000

 cagtttgaga cccaggtgct gtgtcactga ggtggtgccc ctctgcctgc 1050

 ctgccccact gtgctggcag gagctgactg tggactggtg ggctcccctc 1100

 tgggccagca cagtcccctc acctccggca gggctgctac ctcctcagag 1150

 tttcagaagc ccccacatgg gggctctagg aatgccggca tgctggtctt 1200

 tccgacctgg tgctcttctg ctgggggact gaggctggcc ctcattcggg 1250

 gtcgggaacc aagggtgtgt ctgctctttc cctccccatc ctctggcaga 1300

 aatcagctag acgctatacc gtggactctc cctggtccac caccatgttg 1350

 aagcccttgg cagcctgaga gctccaagga acaagctgtg acaaccagga 1400

 gccctgtctg tgggttcgtc tgcccagggc ctggagccca agccctgtgt 1450

 tcctggggaa gctggggact tgggaagtga tgggtgtgtc atgttgcgtg 1500

 tgtctgtctg tgagcctttc acacctgtgc tggcgctgga aaattatttg 1550

 tgctcagctg acatttaaca cttcctcccc cgcttcctcc tagccctgtg 1600

 ggcaggggtt ggaaacttag cactttatat ttatacagaa cattcaggat 1650

 ttgtcaataa aatattgtta tatttaaaaa aaaaaaaaaa aaaaaaaaaa 1700

 aa 1702

<210> 6348
<211> 314
<212> PRT
<213> Homo sapien

<400> 6348
 Met Gly Leu Glu Ala Ala Arg Glu Leu Glu Cys Ala Ala Leu Gly
   1               5                  10                  15

 Thr Leu Leu Arg Asp Pro Arg Glu Ala Glu Arg Thr Leu Leu Leu
                  20                  25                  30

 Asp Cys Arg Pro Phe Leu Ala Phe Cys Arg Arg His Val Arg Ala
                  35                  40                  45

 Ala Arg Pro Val Pro Trp Asn Ala Leu Leu Arg Arg Arg Ala Arg
                  50                  55                  60

 Gly Pro Pro Ala Ala Val Leu Ala Cys Leu Leu Pro Asp Arg Ala
                  65                  70                  75

 Leu Arg Thr Arg Leu Val Arg Gly Glu Leu Ala Arg Ala Val Val
                  80                  85                  90

 Leu Asp Glu Gly Ser Ala Ser Val Ala Glu Leu Arg Pro Asp Ser
                  95                 100                 105

 Pro Ala His Val Leu Leu Ala Ala Leu Leu His Glu Thr Arg Ala
                 110                 115                 120

 Gly Pro Thr Ala Val Tyr Phe Leu Arg Gly Gly Phe Asp Gly Phe
                 125                 130                 135

 Gln Gly Cys Cys Pro Asp Leu Cys Ser Glu Ala Pro Ala Pro Ala
                 140                 145                 150

 Leu Pro Pro Thr Gly Asp Lys Thr Ser Arg Ser Asp Ser Arg Ala
                 155                 160                 165

 Pro Val Tyr Asp Gln Gly Gly Pro Val Glu Ile Leu Pro Tyr Leu
                 170                 175                 180

 Phe Leu Gly Ser Cys Ser His Ser Ser Asp Leu Gln Gly Leu Gln
                 185                 190                 195

 Ala Cys Gly Ile Thr Ala Val Leu Asn Val Ser Ala Ser Cys Pro
                 200                 205                 210

 Asn His Phe Glu Gly Leu Phe Arg Tyr Lys Ser Ile Pro Val Glu
                 215                 220                 225

 Asp Asn Gln Met Val Glu Ile Ser Ala Trp Phe Gln Glu Ala Ile
                 230                 235                 240

 Gly Phe Ile Asp Trp Val Lys Asn Ser Gly Gly Arg Val Leu Val
                 245                 250                 255

 His Cys Gln Ala Gly Ile Ser Arg Ser Ala Thr Ile Cys Leu Ala
                 260                 265                 270

 Tyr Leu Met Gln Ser Arg Arg Val Arg Leu Asp Glu Ala Phe Asp
                 275                 280                 285

 Phe Val Lys Gln Arg Arg Gly Val Ile Ser Pro Asn Phe Ser Phe
                 290                 295                 300

 Met Gly Gln Leu Leu Gln Phe Glu Thr Gln Val Leu Cys His
                 305                 310

<210> 6349
<211> 4432
<212> DNA
<213> Homo sapien

<400> 6349
 gggaagcgcg ccgcgcacct catggttccg gggacagtta gggcggcgga 50

 tggaggtcag cggtggtgct cgctgcggtt tggaatcact tgctaggagt 100

 cttgtctctc tgccacccag gacatcatgg cagctcacct ggtaaagcga 150

 tgcacgtgcc tcctgagaga agctgctcgt caggcccctg ccatggctcc 200

 agttggccga ctgagacttg cctgggtagc ccataagact ctgacttcct 250

 cagccacctc acccatttcc cacctcccag gttccttgat ggagccggtg 300

 gagaaggaac gagcatctac tccctacata gagaagcagg tggaccacct 350

 catcaagaag gccacaaggc cagaggagct cctggagcta cttggtggca 400

 gtcacgactt ggacagcaat caagcagcaa tggtacttat ccggctctct 450

 cacttgctgt ctgagaagcc agaagataaa ggcttgctca tacaggatgc 500

 ccactttcat caacttctct gtctgctcaa cagtcagatt gcctcggtct 550

 ggcatggtac cctctcgaag ctgctgggaa gcctgtatgc tctgggcatc 600

 cccaaggcct ccaaggagct gcagtcggtg gagcaggagg tccgctggcg 650

 catgcggaag ctcaagtaca agcacctggc cttcctggca gagtcctgtg 700

 ccaccctctc acaggagcag cactcgcagg agctgctggc tgagctgctc 750

 acacacctgg aaaggcgttg gacagaaatt gaagattccc acacattagt 800

 gaccgtcatg atgaaggtgg gacacctctc ggagccacta atgaaccgcc 850

 tggaagacaa gcacgtcctg aacagagcgc aggacatcac cctgccccac 900

 ctgtgcagcg tacttctggc ttttgcgcgt ctgaacttcc atccagacca 950

 agaggatcag ttcttcagcc tggtacatga gaagctgggg tcagagctgc 1000

 caggcctgga gccagccctg caggtggacc tggtgtgggc cctgtgtgtg 1050

 ctgcagcagg cacgggaagc agagctgcaa gccgtcctcc accctgaatt 1100

 tcacatccaa tttctagggg gcaagtctca gaaggatcag aacaccttcc 1150

 agaagctgct ccacatcaac gccactgccc tgctggagta ccccgagtac 1200

 tcgggtcccc ttctgcctgc ctcggctgtg gcccctgggc cctcagccct 1250

 tgacaggaag gtgacccccc tgcaaaagga gctgcaggag acgctgaagg 1300

 ggctgctggg gagcgccgac aagggcagcc tcgaggtggc cacgcagtat 1350

 ggctgggtgc tggatgctga ggtgctgctg gacagtgacg gcgagtttct 1400

 gcccgtaagg gactttgtgg cacctcacct tgcccagcca actgggagcc 1450

 agtcaccacc tccagggtct aagaggctag cgttcttgcg gtgggagttc 1500

 cccaacttca acagccgaag caaggacttg ctgggtcgct ttgttctggc 1550

 ccggcgacac atagtggctg caggcttcct gatagtggac gtcccattct 1600

 atgagtggct ggaactcaag tctgaatggc agaaaggcgc ctacctcaag 1650

 gacaagatgc gcaaagcggt ggctgaggag ctggccaagt gacttgtgcc 1700

 agcagcatgg actgcgtgcc tctccgccgg aggtctagct gtgggcggcc 1750

 aagaagggtc acccttgagg acaaacctct gtgcaggacc ttggccagag 1800

 tggggagggt ggccagccac tctgagggac agaacgtcct cttgtgtata 1850

 ataaaccttt aattttggtg ttggacccct ggggccttcc caggcttggt 1900

 caccctctgc actgtcagca cttgtctgtc tgctttgttg agcagggcgt 1950

 ggttctccag tctgccctgt gcactccccc gccacgccca gcccaagagg 2000

 gctgctttag ggacagacct gggttgttac ctgcctgtct ctcccagctt 2050

 cttccctcca tgagtgctta ttcacatatg ccggcctctt gcgtaggggt 2100

 ctgtatcagc cccagcaggc aggtggagtc ctagaattct gaacctccag 2150

 agcagaggag cttcccaggg aagctgattg gagattcagt gcatggctgg 2200

 gggttctgat ggagctgtgg ctactgaacc acagccatcc tgggaggctt 2250

 tctcccatca gttgtctcac acttagctga gtgaaaggca ccctgacagc 2300

 atgtggtgac aggtgatgtg agggctgggt gagcacttgg gaggcgctgg 2350

 ctctgggaga ggagaagatc ccacttggct gacaccacgg caccaagagc 2400

 caaactccat cgttgtcttc accaccctga ccagagcctt gtgctgtcat 2450

 ctaggaactg gctgcccaaa caggaccctg gcagcctccc tgctgctgcg 2500

 gggattacca ggtgctggga ggcaacaagc tttctacctt ccagcctctc 2550

 cttagagaca cctattggca gaacctgact aaatagcagt cagggaactg 2600

 ggttgcctcc agccatacag aacagagagt aggacagtgg ggtggagctg 2650

 agatggagag gcccacagcc ctcagcactg taggctccca accctaggct 2700

 gtttccccaa aaagaaaaag tctagtcact gctctgatgc ttggccactc 2750

 acccaagcat tggggtagtt tgtgctggct tcactgggca ccatcaggca 2800

 cacccagcct gtagtttttg ttttatatta cctaagtcgg ccaggtgtgg 2850

 tgggatcacg cctgtaatcc cagcacttag ggaggctggg gcgggcgaat 2900

 cgcctgaggc caggaattca agaccaacct ggccaacatt gtgaaaccct 2950

 gtctctacta aaaatataaa aattagtcgg gcatgatgac aggcacctgt 3000

 aatcccagct actcaggagg ctgaggcagg tgaatcactt gaacccggga 3050

 ggtggaggct gcagtgagtt aagattgtgc cactgcactc cagcctgggt 3100

 aacagagcaa gactctgtct caaaaaatat atatgtgtgt gtgtgtgtgt 3150

 gtatatatat gtacatgtgt atataagtat atatgtgtgt atatatgtat 3200

 atatacacgt atatacacac acacccctaa gtcatgattt tggagcaatt 3250

 gtaagtggtg tagtgcttaa ttttggcatt cacacattga ttgttagcat 3300

 atagaaatgg gattgatttt tatgtgatct tgctaaactt tatgcatttt 3350

 taaaattcct ttggatttcc tatgtagata tttatgtcct gaaaacagga 3400

 atgtatttat cctttcaaat caatatgctt tttattttgt tatttatgac 3450

 cacttcatta aaatataatt cacatgccat acacttcacc catttaaaat 3500

 gtataattag gccaggtgtg gtggctcacg tctgtaatcc cagcagtttg 3550

 ggaggccaag gccctcagat cttgagccca ggagttcaag accaccctgg 3600

 gcaacaggca aaaccctgtc tctatttttt aaaatacaag aattagccgc 3650

 agtggcacgc acctgtcgtc ccagcaaccc aggaggctga ggtaggagga 3700

 tcacttaagc ctgggaagtc aagcctgcag tgaaccatga tagcaccact 3750

 gcagtccagc ctgggcgaca gagtgagacc ccatctcgaa aacaaaaatg 3800

 tataattcag tggtttttag tctctttgca gatacatgca accatcacca 3850

 caatttgcac attttctaag cctcatatac tgatgtgata ttttggtgtt 3900

 ttgtgactgg cttcatttac ttagcatatt gttttcatgt ttcattcatg 3950

 tcgcatgtat gagtattcat tcctttattt ggctgaataa tattccatta 4000

 tagtttgtgc cacattttgt ttatccattc atccattgat ggacatgtgg 4050

 attgtttcca ccttctggat aatatgaact gatacagttt ggatattttg 4100

 tcccctccaa atctcatgaa ataggatcac cagtgttgga gaatggggcc 4150

 tgttaggaag tgtttggatc ataggaacat ctgtcataaa tggcttggtg 4200

 ccatccttgt aatgagtgag ttcttgctct atattagttc acttgaaagc 4250

 tggttgttgg gaactcctgc cctatctgtt ctgccctctc tcgtcatgtg 4300

 acatgcctgc tccttgttca ccttctgtca tgagtaaaag cttcctaagg 4350

 ccttcccagg agccaagcag atgtcagtac catgcttgta cagcctgcag 4400

 aactgtgagc caaataaact tctttataaa tt 4432

<210> 6350
<211> 521
<212> PRT
<213> Homo sapien

<400> 6350
 Met Ala Ala His Leu Val Lys Arg Cys Thr Cys Leu Leu Arg Glu
   1               5                  10                  15

 Ala Ala Arg Gln Ala Pro Ala Met Ala Pro Val Gly Arg Leu Arg
                  20                  25                  30

 Leu Ala Trp Val Ala His Lys Thr Leu Thr Ser Ser Ala Thr Ser
                  35                  40                  45

 Pro Ile Ser His Leu Pro Gly Ser Leu Met Glu Pro Val Glu Lys
                  50                  55                  60

 Glu Arg Ala Ser Thr Pro Tyr Ile Glu Lys Gln Val Asp His Leu
                  65                  70                  75

 Ile Lys Lys Ala Thr Arg Pro Glu Glu Leu Leu Glu Leu Leu Gly
                  80                  85                  90

 Gly Ser His Asp Leu Asp Ser Asn Gln Ala Ala Met Val Leu Ile
                  95                 100                 105

 Arg Leu Ser His Leu Leu Ser Glu Lys Pro Glu Asp Lys Gly Leu
                 110                 115                 120

 Leu Ile Gln Asp Ala His Phe His Gln Leu Leu Cys Leu Leu Asn
                 125                 130                 135

 Ser Gln Ile Ala Ser Val Trp His Gly Thr Leu Ser Lys Leu Leu
                 140                 145                 150

 Gly Ser Leu Tyr Ala Leu Gly Ile Pro Lys Ala Ser Lys Glu Leu
                 155                 160                 165

 Gln Ser Val Glu Gln Glu Val Arg Trp Arg Met Arg Lys Leu Lys
                 170                 175                 180

 Tyr Lys His Leu Ala Phe Leu Ala Glu Ser Cys Ala Thr Leu Ser
                 185                 190                 195

 Gln Glu Gln His Ser Gln Glu Leu Leu Ala Glu Leu Leu Thr His
                 200                 205                 210

 Leu Glu Arg Arg Trp Thr Glu Ile Glu Asp Ser His Thr Leu Val
                 215                 220                 225

 Thr Val Met Met Lys Val Gly His Leu Ser Glu Pro Leu Met Asn
                 230                 235                 240

 Arg Leu Glu Asp Lys His Val Leu Asn Arg Ala Gln Asp Ile Thr
                 245                 250                 255

 Leu Pro His Leu Cys Ser Val Leu Leu Ala Phe Ala Arg Leu Asn
                 260                 265                 270

 Phe His Pro Asp Gln Glu Asp Gln Phe Phe Ser Leu Val His Glu
                 275                 280                 285

 Lys Leu Gly Ser Glu Leu Pro Gly Leu Glu Pro Ala Leu Gln Val
                 290                 295                 300

 Asp Leu Val Trp Ala Leu Cys Val Leu Gln Gln Ala Arg Glu Ala
                 305                 310                 315

 Glu Leu Gln Ala Val Leu His Pro Glu Phe His Ile Gln Phe Leu
                 320                 325                 330

 Gly Gly Lys Ser Gln Lys Asp Gln Asn Thr Phe Gln Lys Leu Leu
                 335                 340                 345

 His Ile Asn Ala Thr Ala Leu Leu Glu Tyr Pro Glu Tyr Ser Gly
                 350                 355                 360

 Pro Leu Leu Pro Ala Ser Ala Val Ala Pro Gly Pro Ser Ala Leu
                 365                 370                 375

 Asp Arg Lys Val Thr Pro Leu Gln Lys Glu Leu Gln Glu Thr Leu
                 380                 385                 390

 Lys Gly Leu Leu Gly Ser Ala Asp Lys Gly Ser Leu Glu Val Ala
                 395                 400                 405

 Thr Gln Tyr Gly Trp Val Leu Asp Ala Glu Val Leu Leu Asp Ser
                 410                 415                 420

 Asp Gly Glu Phe Leu Pro Val Arg Asp Phe Val Ala Pro His Leu
                 425                 430                 435

 Ala Gln Pro Thr Gly Ser Gln Ser Pro Pro Pro Gly Ser Lys Arg
                 440                 445                 450

 Leu Ala Phe Leu Arg Trp Glu Phe Pro Asn Phe Asn Ser Arg Ser
                 455                 460                 465

 Lys Asp Leu Leu Gly Arg Phe Val Leu Ala Arg Arg His Ile Val
                 470                 475                 480

 Ala Ala Gly Phe Leu Ile Val Asp Val Pro Phe Tyr Glu Trp Leu
                 485                 490                 495

 Glu Leu Lys Ser Glu Trp Gln Lys Gly Ala Tyr Leu Lys Asp Lys
                 500                 505                 510

 Met Arg Lys Ala Val Ala Glu Glu Leu Ala Lys
                 515                 520

<210> 6351
<211> 4484
<212> DNA
<213> Homo sapien

<400> 6351
 tgcccaggag gagtaggagc aggagcagaa gcagaagcgg ggtccggagc 50

 tgcgcgccta cgcgggacct gtgtccgaaa tgccggtgcg aggagaccgc 100

 gggtttccac cccggcggga gctgtcaggt tggctccgcg ccccaggcat 150

 ggaagagctg atatgggaac agtacactgt gaccctacaa aaggattcca 200

 aaagaggatt tggaattgca gtgtccggag gcagagacaa cccccacttt 250

 gaaaatggag aaacgtcaat tgtcatttct gatgtgctcc cgggtgggcc 300

 tgctgatggg ctgctccaag aaaatgacag agtggtcatg gtcaatggca 350

 cccccatgga ggatgtgctt cattcgtttg cagttcagca gctcagaaaa 400

 agtgggaagg tcgctgctat tgtggtcaag aggccccgga aggtccaggt 450

 ggccgcactt caggccagcc ctcccctgga tcaggatgac cgggcttttg 500

 aggtgatgga cgagtttgat ggcagaagtt tccggagtgg ctacagcgag 550

 aggagccggc tgaacagcca tggggggcgc agccgcagct gggaggacag 600

 cccggaaagg gggcgtcccc atgagcgggc ccggagccgg gagcgggacc 650

 tcagccggga ccggagccgt ggccggagcc tggagcgggg cctggaccaa 700

 gaccatgcgc gcacccgaga ccgcagccgt ggccggagcc tggagcgggg 750

 cctggaccac gactttgggc catcccggga ccgggaccgt gaccgcagcc 800

 gcggccggag cattgaccag gactacgagc gagcctatca ccgggcctac 850

 gacccagact acgagcgggc ctacagcccg gagtacaggc gcggggcccg 900

 ccacgatgcc cgctctcggg gaccccgaag ccgcagccgc gagcacccgc 950

 actcacggag ccccagcccc gagcctaggg ggcggccggg gcccatcggg 1000

 gtcctcctga tgaaaagcag agcgaacgaa gagtatggtc tccggcttgg 1050

 gagtcagatc ttcgtaaagg aaatgacccg aacgggtctg gcaactaaag 1100

 atggcaacct tcacgaagga gacataattc tcaagatcaa tgggactgta 1150

 actgagaaca tgtctttaac ggatgctcga aaattgatag aaaagtcaag 1200

 aggaaaacta cagctagtgg tgttgagaga cagccagcag accctcatca 1250

 acatcccgtc attaaatgac agtgactcag aaatagaaga tatttcagaa 1300

 atagagtcaa cccgatcatt ttctccagag gagagacgtc atcagtattc 1350

 tgattatgat tatcattcct caagtgagaa gctgaaggaa aggccaagtt 1400

 ccagagagga cacgccgagc agattgtcca ggatgggtgc gacacccact 1450

 ccctttaagt ccacagggga tattgcaggc acagttgtcc cagagaccaa 1500

 caaggaaccc agataccaag aggaaccccc agctcctcaa ccaaaagcag 1550

 ccccgagaac ttttcttcgt cctagtcctg aagatgaagc aatatatggc 1600

 cctaatacca aaatggtaag gttcaagaag ggagacagcg tgggcctccg 1650

 gttggctggt ggcaatgatg tcgggatatt tgttgctggc attcaagaag 1700

 ggacctcggc ggagcaggag ggccttcaag aaggagacca gattctgaag 1750

 gtgaacacac aggatttcag aggattagtg cgggaggatg ccgttctcta 1800

 cctgttagaa atccctaaag gtgaaatggt gaccatttta gctcagagcc 1850

 gagccgatgt gtatagagac atcctggctt gtggcagagg ggattcgttt 1900

 tttataagaa gccactttga atgtgagaag gaaactccac agagcctggc 1950

 cttcaccaga ggggaggtct tccgagtggt agacacactg tatgacggca 2000

 agctgggcaa ctggctggct gtgaggattg ggaacgagtt ggagaaaggc 2050

 ttaatcccca acaagagcag agctgaacaa atggccagtg ttcaaaatgc 2100

 ccagagagac aacgctgggg accgggcaga tttctggaga atgcgtggcc 2150

 agaggtctgg ggtgaagaag aacctgagga aaagtcggga agacctcaca 2200

 gctgttgtgt ctgtcagcac caagttccca gcttatgaga gggttttgct 2250

 gcgagaagct ggtttcaaga gacctgtggt cttattcggc cccatagctg 2300

 atatagcaat ggaaaaattg gctaatgagt tacctgactg gtttcaaact 2350

 gctaaaacgg aaccaaaaga tgcaggatct gagaaatcca ctggagtggt 2400

 ccggttaaat accgtgaggc aagttattga acaggataag catgcactac 2450

 tggatgtgac tccgaaagct gtggacctgt tgaattacac ccagtggttc 2500

 tcaattgtga tttctttcac gccagactcc agacaaggtg tcaacaccat 2550

 gagacaaagg ttagacccaa cgtccaacaa tagttctcga aagttatttg 2600

 atcacgccaa caagcttaaa aaaacgtgtg cacacctttt tacagctaca 2650

 atcaacctaa attcagccaa tgatagctgg tttggcagct taaaggacac 2700

 tattcagcat cagcaaggag aagcggtttg ggtctctgaa ggaaagatgg 2750

 aagggatgga tgatgacccc gaagaccgca tgtcctactt aactgccatg 2800

 ggcgcagact atctgagttg cgacagccgc ctcatcagtg actttgaaga 2850

 cacggacggt gaaggaggcg cctacactga caatgagctg gatgagccag 2900

 ccgaggagcc gctggtgtcg tccatcaccc gctcctcgga gccggtgcag 2950

 cacgaggaga gcataaggaa acccagccca gagccacgag ctcagatgag 3000

 gagggctgct agcagcgatc aacttaggga caatagcccg cccccagcat 3050

 tcaagccaga gccgtccaag gccaaaaccc agaacaaaga agaatcctat 3100

 gacttctcca aatcctatga atataagtca aacccctctg ccgttgctgg 3150

 taatgaaact cctggggcat ctaccaaagg ttatcctcct cctgttgcag 3200

 caaaacctac ctttgggcgg tctatactga agccctccac tcccatccct 3250

 cctcaagagg gtgaggaggt gggagagagc agtgaggagc aagataatgc 3300

 tcccaaatca gtcctgggca aagtcaaaat atttggagaa gatggatcac 3350

 aagggccagg gttacaagag aatgcaggag ctccaggaag cacagaatgc 3400

 aaggatcgaa attgcccaga agcatcctga tatctatgca gttccaatca 3450

 aaacgcacaa gccagaccct ggcacgcccc agcacacgag ttccagaccc 3500

 cctgagccac agaaagctcc ttccagacct tatcaggata ccagaggaag 3550

 ttatggcagt gatgccgagg aggaggagta ccgccagcag ctgtcagaac 3600

 actccaagcg cggttactat ggccagtctg cccgataccg ggacacagaa 3650

 ttatagatgt ctgagcacgg actctcccag gcctgcctgc atggcatcag 3700

 actagccact cctgccaggc cgccgggatg gttcttctcc agttagaatg 3750

 caccatggag acgtggtggg actccagctc gtgtgtcctc atggagaacc 3800

 caggggacag ctggtgcaaa ttcagaactg agggctctgt ttgtgggact 3850

 gggttagagg agtctgtggc tttttgttca gaattaagca gaacactgca 3900

 gtcagatcct gttacttgct tcagtggacc gaaatctgta ttctgtttgc 3950

 gtacttgtaa tatgtatatt aagaagcaat aactattttt cctcattaat 4000

 agctgccttc aaggactgtt tcagtgtgag tcagaatgtg aaaaaggaat 4050

 aaaaaatact gttgggctca aactaaattc aaagaagtac tttattgcaa 4100

 ctcttttaag tgccttggat gagaagtgtc ttaaattttc ttcctttgaa 4150

 gctttaggca gagccataat ggactaaaac attttgacta agtttttata 4200

 ccagcttaat agctgtagtt ttccctgcac tgtgtcatct tttcaaggca 4250

 tttgtctttg taatattttc cataaatttg gactgtctat atcataacta 4300

 tacttgatag tttggctata agtgctcaat agcttgaagc ccaagaagtt 4350

 ggtatcgaaa tttgttgttt gtttaaaccc aagtgctgca caaaagcaga 4400

 tacttgagga aaacactatt tccaaaagca catgtattga caacagtttt 4450

 ataatttaat aaaaaggaat acattgcaat ccgt 4484

<210> 6352
<211> 1116
<212> PRT
<213> Homo sapien

<400> 6352
 Met Pro Val Arg Gly Asp Arg Gly Phe Pro Pro Arg Arg Glu Leu
   1               5                  10                  15

 Ser Gly Trp Leu Arg Ala Pro Gly Met Glu Glu Leu Ile Trp Glu
                  20                  25                  30

 Gln Tyr Thr Val Thr Leu Gln Lys Asp Ser Lys Arg Gly Phe Gly
                  35                  40                  45

 Ile Ala Val Ser Gly Gly Arg Asp Asn Pro His Phe Glu Asn Gly
                  50                  55                  60

 Glu Thr Ser Ile Val Ile Ser Asp Val Leu Pro Gly Gly Pro Ala
                  65                  70                  75

 Asp Gly Leu Leu Gln Glu Asn Asp Arg Val Val Met Val Asn Gly
                  80                  85                  90

 Thr Pro Met Glu Asp Val Leu His Ser Phe Ala Val Gln Gln Leu
                  95                 100                 105

 Arg Lys Ser Gly Lys Val Ala Ala Ile Val Val Lys Arg Pro Arg
                 110                 115                 120

 Lys Val Gln Val Ala Ala Leu Gln Ala Ser Pro Pro Leu Asp Gln
                 125                 130                 135

 Asp Asp Arg Ala Phe Glu Val Met Asp Glu Phe Asp Gly Arg Ser
                 140                 145                 150

 Phe Arg Ser Gly Tyr Ser Glu Arg Ser Arg Leu Asn Ser His Gly
                 155                 160                 165

 Gly Arg Ser Arg Ser Trp Glu Asp Ser Pro Glu Arg Gly Arg Pro
                 170                 175                 180

 His Glu Arg Ala Arg Ser Arg Glu Arg Asp Leu Ser Arg Asp Arg
                 185                 190                 195

 Ser Arg Gly Arg Ser Leu Glu Arg Gly Leu Asp Gln Asp His Ala
                 200                 205                 210

 Arg Thr Arg Asp Arg Ser Arg Gly Arg Ser Leu Glu Arg Gly Leu
                 215                 220                 225

 Asp His Asp Phe Gly Pro Ser Arg Asp Arg Asp Arg Asp Arg Ser
                 230                 235                 240

 Arg Gly Arg Ser Ile Asp Gln Asp Tyr Glu Arg Ala Tyr His Arg
                 245                 250                 255

 Ala Tyr Asp Pro Asp Tyr Glu Arg Ala Tyr Ser Pro Glu Tyr Arg
                 260                 265                 270

 Arg Gly Ala Arg His Asp Ala Arg Ser Arg Gly Pro Arg Ser Arg
                 275                 280                 285

 Ser Arg Glu His Pro His Ser Arg Ser Pro Ser Pro Glu Pro Arg
                 290                 295                 300

 Gly Arg Pro Gly Pro Ile Gly Val Leu Leu Met Lys Ser Arg Ala
                 305                 310                 315

 Asn Glu Glu Tyr Gly Leu Arg Leu Gly Ser Gln Ile Phe Val Lys
                 320                 325                 330

 Glu Met Thr Arg Thr Gly Leu Ala Thr Lys Asp Gly Asn Leu His
                 335                 340                 345

 Glu Gly Asp Ile Ile Leu Lys Ile Asn Gly Thr Val Thr Glu Asn
                 350                 355                 360

 Met Ser Leu Thr Asp Ala Arg Lys Leu Ile Glu Lys Ser Arg Gly
                 365                 370                 375

 Lys Leu Gln Leu Val Val Leu Arg Asp Ser Gln Gln Thr Leu Ile
                 380                 385                 390

 Asn Ile Pro Ser Leu Asn Asp Ser Asp Ser Glu Ile Glu Asp Ile
                 395                 400                 405

 Ser Glu Ile Glu Ser Thr Arg Ser Phe Ser Pro Glu Glu Arg Arg
                 410                 415                 420

 His Gln Tyr Ser Asp Tyr Asp Tyr His Ser Ser Ser Glu Lys Leu
                 425                 430                 435

 Lys Glu Arg Pro Ser Ser Arg Glu Asp Thr Pro Ser Arg Leu Ser
                 440                 445                 450

 Arg Met Gly Ala Thr Pro Thr Pro Phe Lys Ser Thr Gly Asp Ile
                 455                 460                 465

 Ala Gly Thr Val Val Pro Glu Thr Asn Lys Glu Pro Arg Tyr Gln
                 470                 475                 480

 Glu Glu Pro Pro Ala Pro Gln Pro Lys Ala Ala Pro Arg Thr Phe
                 485                 490                 495

 Leu Arg Pro Ser Pro Glu Asp Glu Ala Ile Tyr Gly Pro Asn Thr
                 500                 505                 510

 Lys Met Val Arg Phe Lys Lys Gly Asp Ser Val Gly Leu Arg Leu
                 515                 520                 525

 Ala Gly Gly Asn Asp Val Gly Ile Phe Val Ala Gly Ile Gln Glu
                 530                 535                 540

 Gly Thr Ser Ala Glu Gln Glu Gly Leu Gln Glu Gly Asp Gln Ile
                 545                 550                 555

 Leu Lys Val Asn Thr Gln Asp Phe Arg Gly Leu Val Arg Glu Asp
                 560                 565                 570

 Ala Val Leu Tyr Leu Leu Glu Ile Pro Lys Gly Glu Met Val Thr
                 575                 580                 585

 Ile Leu Ala Gln Ser Arg Ala Asp Val Tyr Arg Asp Ile Leu Ala
                 590                 595                 600

 Cys Gly Arg Gly Asp Ser Phe Phe Ile Arg Ser His Phe Glu Cys
                 605                 610                 615

 Glu Lys Glu Thr Pro Gln Ser Leu Ala Phe Thr Arg Gly Glu Val
                 620                 625                 630

 Phe Arg Val Val Asp Thr Leu Tyr Asp Gly Lys Leu Gly Asn Trp
                 635                 640                 645

 Leu Ala Val Arg Ile Gly Asn Glu Leu Glu Lys Gly Leu Ile Pro
                 650                 655                 660

 Asn Lys Ser Arg Ala Glu Gln Met Ala Ser Val Gln Asn Ala Gln
                 665                 670                 675

 Arg Asp Asn Ala Gly Asp Arg Ala Asp Phe Trp Arg Met Arg Gly
                 680                 685                 690

 Gln Arg Ser Gly Val Lys Lys Asn Leu Arg Lys Ser Arg Glu Asp
                 695                 700                 705

 Leu Thr Ala Val Val Ser Val Ser Thr Lys Phe Pro Ala Tyr Glu
                 710                 715                 720

 Arg Val Leu Leu Arg Glu Ala Gly Phe Lys Arg Pro Val Val Leu
                 725                 730                 735

 Phe Gly Pro Ile Ala Asp Ile Ala Met Glu Lys Leu Ala Asn Glu
                 740                 745                 750

 Leu Pro Asp Trp Phe Gln Thr Ala Lys Thr Glu Pro Lys Asp Ala
                 755                 760                 765

 Gly Ser Glu Lys Ser Thr Gly Val Val Arg Leu Asn Thr Val Arg
                 770                 775                 780

 Gln Val Ile Glu Gln Asp Lys His Ala Leu Leu Asp Val Thr Pro
                 785                 790                 795

 Lys Ala Val Asp Leu Leu Asn Tyr Thr Gln Trp Phe Ser Ile Val
                 800                 805                 810

 Ile Ser Phe Thr Pro Asp Ser Arg Gln Gly Val Asn Thr Met Arg
                 815                 820                 825

 Gln Arg Leu Asp Pro Thr Ser Asn Asn Ser Ser Arg Lys Leu Phe
                 830                 835                 840

 Asp His Ala Asn Lys Leu Lys Lys Thr Cys Ala His Leu Phe Thr
                 845                 850                 855

 Ala Thr Ile Asn Leu Asn Ser Ala Asn Asp Ser Trp Phe Gly Ser
                 860                 865                 870

 Leu Lys Asp Thr Ile Gln His Gln Gln Gly Glu Ala Val Trp Val
                 875                 880                 885

 Ser Glu Gly Lys Met Glu Gly Met Asp Asp Asp Pro Glu Asp Arg
                 890                 895                 900

 Met Ser Tyr Leu Thr Ala Met Gly Ala Asp Tyr Leu Ser Cys Asp
                 905                 910                 915

 Ser Arg Leu Ile Ser Asp Phe Glu Asp Thr Asp Gly Glu Gly Gly
                 920                 925                 930

 Ala Tyr Thr Asp Asn Glu Leu Asp Glu Pro Ala Glu Glu Pro Leu
                 935                 940                 945

 Val Ser Ser Ile Thr Arg Ser Ser Glu Pro Val Gln His Glu Glu
                 950                 955                 960

 Ser Ile Arg Lys Pro Ser Pro Glu Pro Arg Ala Gln Met Arg Arg
                 965                 970                 975

 Ala Ala Ser Ser Asp Gln Leu Arg Asp Asn Ser Pro Pro Pro Ala
                 980                 985                 990

 Phe Lys Pro Glu Pro Ser Lys Ala Lys Thr Gln Asn Lys Glu Glu
                 995                1000                1005

 Ser Tyr Asp Phe Ser Lys Ser Tyr Glu Tyr Lys Ser Asn Pro Ser
                1010                1015                1020

 Ala Val Ala Gly Asn Glu Thr Pro Gly Ala Ser Thr Lys Gly Tyr
                1025                1030                1035

 Pro Pro Pro Val Ala Ala Lys Pro Thr Phe Gly Arg Ser Ile Leu
                1040                1045                1050

 Lys Pro Ser Thr Pro Ile Pro Pro Gln Glu Gly Glu Glu Val Gly
                1055                1060                1065

 Glu Ser Ser Glu Glu Gln Asp Asn Ala Pro Lys Ser Val Leu Gly
                1070                1075                1080

 Lys Val Lys Ile Phe Gly Glu Asp Gly Ser Gln Gly Pro Gly Leu
                1085                1090                1095

 Gln Glu Asn Ala Gly Ala Pro Gly Ser Thr Glu Cys Lys Asp Arg
                1100                1105                1110

 Asn Cys Pro Glu Ala Ser
                1115

<210> 6353
<211> 2032
<212> DNA
<213> Homo sapien

<400> 6353
 actcagtgtt cgcgggagcg ccgcacctac accagccaac ccagatcccg 50

 aggtccgaca gcgcccggcc cagatcccca cgcctgccag gagcaagccg 100

 agagccagcc ggccggcgca ctccgactcc gagcagtctc tgtccttcga 150

 cccgagcccc gcgccctttc cgggacccct gccccgcggg cagcgctgcc 200

 aacctgccgg ccatggagac cccgtcccag cggcgcgcca cccgcagcgg 250

 ggcgcaggcc agctccactc cgctgtcgcc cacccgcatc acccggctgc 300

 aggagaagga ggacctgcag gagctcaatg atcgcttggc ggtctacatc 350

 gaccgtgtgc gctcgctgga aacggagaac gcagggctgc gccttcgcat 400

 caccgagtct gaagaggtgg tcagccgcga ggtgtccggc atcaaggccg 450

 cctacgaggc cgagctcggg gatgcccgca agacccttga ctcagtagcc 500

 aaggagcgcg cccgcctgca gctggagctg agcaaagtgc gtgaggagtt 550

 taaggagctg aaagcgcgca ataccaagaa ggagggtgac ctgatagctg 600

 ctcaggctcg gctgaaggac ctggaggctc tgctgaactc caaggaggcc 650

 gcactgagca ctgctctcag tgagaagcgc acgctggagg gcgagctgca 700

 tgatctgcgg ggccaggtgg ccaagcttga ggcagcccta ggtgaggcca 750

 agaagcaact tcaggatgag atgctgcggc gggtggatgc tgagaacagg 800

 ctgcagacca tgaaggagga actggacttc cagaagaaca tctacagtga 850

 ggagctgcgt gagaccaagc gccgtcatga gacccgactg gtggagattg 900

 acaatgggaa gcagcgtgag tttgagagcc ggctggcgga tgcgctgcag 950

 gaactgcggg cccagcatga ggaccaggtg gagcagtata agaaggagct 1000

 ggagaagact tattctgcca agctggacaa tgccaggcag tctgctgaga 1050

 ggaacagcaa cctggtgggg gctgcccacg aggagctgca gcagtcgcgc 1100

 atccgcatcg acagcctctc tgcccagctc agccagctcc agaagcagct 1150

 ggcagccaag gaggcgaagc ttcgagacct ggaggactca ctggcccgtg 1200

 agcgggacac cagccggcgg ctgctggcgg aaaaggagcg ggagatggcc 1250

 gagatgcggg caaggatgca gcagcagctg gacgagtacc aggagcttct 1300

 ggacatcaag ctggccctgg acatggagat ccacgcctac cgcaagctct 1350

 tggagggcga ggaggagagg ctacgcctgt cccccagccc tacctcgcag 1400

 cgcagccgtg gccgtgcttc ctctcactca tcccagacac agggtggggg 1450

 cagcgtcacc aaaaagcgca aactggagtc cactgagagc cgcagcagct 1500

 tctcacagca cgcacgcact agcgggcgcg tggccgtgga ggaggtggat 1550

 gaggagggca agtttgtccg gctgcgcaac aagtccaatg aggaccagtc 1600

 catgggcaat tggcagatca agcgccagaa tggagatgat cccttgctga 1650

 cttaccggtt cccaccaaag ttcaccctga aggctgggca ggtggtgacg 1700

 atctgggctg caggagctgg ggccacccac agccccccta ccgacctggt 1750

 gtggaaggca cagaacacct ggggctgcgg gaacagcctg cgtacggctc 1800

 tcatcaactc cactggggaa gaagtggcca tgcgcaagct ggtgcgctca 1850

 gtgactgtgg ttgaggacga cgaggatgag gatggagatg acctgctcca 1900

 tcaccaccac gtgagtggta gccgccgctg aggccgagcc tgcactgggg 1950

 ccacccagcc aggcctgggg gcagcctctc cccagcctcc ccgtgccaaa 2000

 aatcttttca ttaaagaatg ttttggaact tt 2032

<210> 6354
<211> 572
<212> PRT
<213> Homo sapien

<400> 6354
 Met Glu Thr Pro Ser Gln Arg Arg Ala Thr Arg Ser Gly Ala Gln
   1               5                  10                  15

 Ala Ser Ser Thr Pro Leu Ser Pro Thr Arg Ile Thr Arg Leu Gln
                  20                  25                  30

 Glu Lys Glu Asp Leu Gln Glu Leu Asn Asp Arg Leu Ala Val Tyr
                  35                  40                  45

 Ile Asp Arg Val Arg Ser Leu Glu Thr Glu Asn Ala Gly Leu Arg
                  50                  55                  60

 Leu Arg Ile Thr Glu Ser Glu Glu Val Val Ser Arg Glu Val Ser
                  65                  70                  75

 Gly Ile Lys Ala Ala Tyr Glu Ala Glu Leu Gly Asp Ala Arg Lys
                  80                  85                  90

 Thr Leu Asp Ser Val Ala Lys Glu Arg Ala Arg Leu Gln Leu Glu
                  95                 100                 105

 Leu Ser Lys Val Arg Glu Glu Phe Lys Glu Leu Lys Ala Arg Asn
                 110                 115                 120

 Thr Lys Lys Glu Gly Asp Leu Ile Ala Ala Gln Ala Arg Leu Lys
                 125                 130                 135

 Asp Leu Glu Ala Leu Leu Asn Ser Lys Glu Ala Ala Leu Ser Thr
                 140                 145                 150

 Ala Leu Ser Glu Lys Arg Thr Leu Glu Gly Glu Leu His Asp Leu
                 155                 160                 165

 Arg Gly Gln Val Ala Lys Leu Glu Ala Ala Leu Gly Glu Ala Lys
                 170                 175                 180

 Lys Gln Leu Gln Asp Glu Met Leu Arg Arg Val Asp Ala Glu Asn
                 185                 190                 195

 Arg Leu Gln Thr Met Lys Glu Glu Leu Asp Phe Gln Lys Asn Ile
                 200                 205                 210

 Tyr Ser Glu Glu Leu Arg Glu Thr Lys Arg Arg His Glu Thr Arg
                 215                 220                 225

 Leu Val Glu Ile Asp Asn Gly Lys Gln Arg Glu Phe Glu Ser Arg
                 230                 235                 240

 Leu Ala Asp Ala Leu Gln Glu Leu Arg Ala Gln His Glu Asp Gln
                 245                 250                 255

 Val Glu Gln Tyr Lys Lys Glu Leu Glu Lys Thr Tyr Ser Ala Lys
                 260                 265                 270

 Leu Asp Asn Ala Arg Gln Ser Ala Glu Arg Asn Ser Asn Leu Val
                 275                 280                 285

 Gly Ala Ala His Glu Glu Leu Gln Gln Ser Arg Ile Arg Ile Asp
                 290                 295                 300

 Ser Leu Ser Ala Gln Leu Ser Gln Leu Gln Lys Gln Leu Ala Ala
                 305                 310                 315

 Lys Glu Ala Lys Leu Arg Asp Leu Glu Asp Ser Leu Ala Arg Glu
                 320                 325                 330

 Arg Asp Thr Ser Arg Arg Leu Leu Ala Glu Lys Glu Arg Glu Met
                 335                 340                 345

 Ala Glu Met Arg Ala Arg Met Gln Gln Gln Leu Asp Glu Tyr Gln
                 350                 355                 360

 Glu Leu Leu Asp Ile Lys Leu Ala Leu Asp Met Glu Ile His Ala
                 365                 370                 375

 Tyr Arg Lys Leu Leu Glu Gly Glu Glu Glu Arg Leu Arg Leu Ser
                 380                 385                 390

 Pro Ser Pro Thr Ser Gln Arg Ser Arg Gly Arg Ala Ser Ser His
                 395                 400                 405

 Ser Ser Gln Thr Gln Gly Gly Gly Ser Val Thr Lys Lys Arg Lys
                 410                 415                 420

 Leu Glu Ser Thr Glu Ser Arg Ser Ser Phe Ser Gln His Ala Arg
                 425                 430                 435

 Thr Ser Gly Arg Val Ala Val Glu Glu Val Asp Glu Glu Gly Lys
                 440                 445                 450

 Phe Val Arg Leu Arg Asn Lys Ser Asn Glu Asp Gln Ser Met Gly
                 455                 460                 465

 Asn Trp Gln Ile Lys Arg Gln Asn Gly Asp Asp Pro Leu Leu Thr
                 470                 475                 480

 Tyr Arg Phe Pro Pro Lys Phe Thr Leu Lys Ala Gly Gln Val Val
                 485                 490                 495

 Thr Ile Trp Ala Ala Gly Ala Gly Ala Thr His Ser Pro Pro Thr
                 500                 505                 510

 Asp Leu Val Trp Lys Ala Gln Asn Thr Trp Gly Cys Gly Asn Ser
                 515                 520                 525

 Leu Arg Thr Ala Leu Ile Asn Ser Thr Gly Glu Glu Val Ala Met
                 530                 535                 540

 Arg Lys Leu Val Arg Ser Val Thr Val Val Glu Asp Asp Glu Asp
                 545                 550                 555

 Glu Asp Gly Asp Asp Leu Leu His His His His Val Ser Gly Ser
                 560                 565                 570

 Arg Arg


<210> 6355
<211> 3615
<212> DNA
<213> Homo sapien

<400> 6355
 ggactgtgtg tgtctggctg tagcagacgc gaggcggcga cgaggcgccg 50

 gggacccgcg cgaggggcgg ccgggaggcg gcggcggcgg ccgccagaag 100

 tagcagcagg accggcggcg gcgacggcag ccctgaaatg cattttcctc 150

 tccagcggcc atgttaacca ggaaaccttc ggccgccgct cccgccgcct 200

 acccgaccgg ccgaggtggg gacagcgccg ttcgtcagct tcaggcttcc 250

 ccggggctcg gtgcagggcc cacccggagc ggagtgggga ctggcccgcc 300

 ctcccccatc gccctgccgc ctctccgggc cagcaacgct gccgccgcag 350

 cccacacgat tggcggcagt aagcacacaa tgaatgatca cctgcatgtc 400

 ggcagccacg ctcacggaca gatccaggtt caacagttgt ttgaggataa 450

 cagtaacaag cggacagtgc tcacgacaca accaaatggg cttacaacag 500

 tgggcaaaac gggcttgcca gtggtgccag agcggcagct ggacagcatt 550

 catagacggc aggggagctc cacctctcta aagtccatgg aaggcatggg 600

 gaaggtgaaa gccaccccca tgacacctga acaagcaatg aagcaataca 650

 tgcaaaaact cacagccttc gaacaccatg agattttcag ctaccctgaa 700

 atatatttct tgggtctaaa tgctaagaag cgccagggca tgacaggtgg 750

 gcccaacaat ggtggctatg atgatgacca gggatcatat gtgcaggtgc 800

 cccacgatca cgtggcttac aggtatgagg tcctcaaggt cattgggaag 850

 gggagctttg ggcaggtggt caaggcctac gatcacaaag tccaccagca 900

 cgtggcccta aagatggtgc ggaatgagaa gcgcttccac cggcaagcag 950

 cggaggagat ccgaatcctg gaacacctgc ggaagcagga caaggataac 1000

 acaatgaatg tcatccatat gctggagaat ttcaccttcc gcaaccacat 1050

 ctgcatgacg tttgagctgc tgagcatgaa cctctatgag ctcatcaaga 1100

 agaataaatt ccagggcttc agtctgcctt tggttcgcaa gtttgcccac 1150

 tcgattctgc agtgcttgga tgctttgcac aaaaacagaa taattcactg 1200

 tgaccttaag cccgagaaca ttttgttaaa gcagcagggt agaagcggta 1250

 ttaaagtaat tgattttggc tccagttgtt acgagcatca gcgtgtctac 1300

 acgtacatcc agtcgcgttt ttaccgggct ccagaagtga tccttggggc 1350

 caggtatggc atgcccattg atatgtggag cctgggctgc attttagcag 1400

 agctcctgac gggttacccc ctcttgcctg gggaagatga aggggaccag 1450

 ctggcctgta tgattgaact gttgggcatg ccctcacaga aactgctgga 1500

 tgcatccaaa cgagccaaaa attttgtgag ctccaagggt tatccccgtt 1550

 actgcactgt cacgactctc tcagatggct ctgtggtcct aaacggaggc 1600

 cgttcccgga gggggaaact gaggggccca ccggagagca gagagtgggg 1650

 gaacgcgctg aaggggtgtg atgatcccct tttccttgac ttcttaaaac 1700

 agtgtttaga gtgggatcct gcagtgcgca tgaccccagg ccaggctttg 1750

 cggcacccct ggctgaggag gcggttgcca aagcctccca ccggggagaa 1800

 aacgtcagtg aaaaggataa ctgagagcac cggtgctatc acatctatat 1850

 ccaagttacc tccaccttct agctcagctt ccaaactgag gactaatttg 1900

 gcgcagatga cagatgccaa tgggaatatt cagcagagga cagtgttgcc 1950

 aaaacttgtt agctgagctc acgtcccctg atgctggtaa cctgaaagat 2000

 acgacattgc tgagccttac tgggttgaaa aggagtagct cagacctgtt 2050

 tttatttgct caataactct actcatttgt atcttttcag cacttaattt 2100

 taatgtaaga aagttgttca ttttgttttt ataaaataca tgaggacaat 2150

 gctttaagtt tttatacttt cagaaacttt ttgtgttcta aaagtacaat 2200

 gagccttact gtatttagtg tggcagaata ataacatcag tggcaggcca 2250

 ctgattactt catgactgcc acgcatttac agattggtgt caaagacatt 2300

 cactatgttt ttatggttca tgttatatcc tccccagggt gacagcccct 2350

 taaggccctc cttttccctc catgctccag gtccatgcac aggtgtagca 2400

 tgtcctgctt ccgtttttca taaattaatc tgggtgttgg gggtagtggg 2450

 aggagaacgg tcagaatcaa agtgacattc taagaaaaac tgtaccttag 2500

 agattttcct ctagtgctca aacaaataca aaataagatc cccaaggttt 2550

 aaactgccca gttagcattc tgacattcta aaagccggca aagcagcttt 2600

 tagtggataa atgggaatgg aaacgtgtgt gttcctccaa attttctagt 2650

 atgatcggtg agctgttttg taaagaagcc tcatattaca gagttgcttt 2700

 tgcacctaaa tttagaattg tattccatga actgttcctc ccttttctct 2750

 gcttttctcc tctctgttcc tcttttaata ccacacgtct gttgcttgca 2800

 tttagtttgt cttcttcctt cagctgtgta tcccagactg ttaatacaga 2850

 aaagagacat ttcagctgtg attatgacca ttgtttcata ttccaattaa 2900

 aaaaagaaca gcagcctagc tacttaaggt ggggatttca tagttccaaa 2950

 gaagatttag cagattagag tgagttcaca cttttcaggt gccactgtaa 3000

 ggttctctca gcctgggaaa ctatcaactc tttctttaaa aagaaagagg 3050

 gttgaaaatc ctctggacga acagaagtca ctttggctgt tcagtaaggc 3100

 caatgttaac aacacgttta gaggaggaaa agttcaacct caagttaaat 3150

 ggtttgactt attcttcgta tcattagaag aaccccagag atagcattcc 3200

 tctattttat tttactttct tttggattgc actgattgtt tttgtgggaa 3250

 tgacacttta tctggcaaag taactgagag tttggtaaaa gaatattttc 3300

 ttctctgaat aataattatt ttcacagtga aaatttcagt attttatcac 3350

 taatgtatga gcaatgatct atatcaattt caaggcacgt gaaaaaaatt 3400

 ttttagtatg tgcaatttaa tatagaaaga tttctgcctg tttggacaat 3450

 aggttttggg tagtacagat taggataagt aagcttatat atgcacagag 3500

 attattgtat tacctgtaaa ttgatttaca agtacttaaa agcgtggtcc 3550

 ccagtgaggc caagaaagtt tccggttaag ttctttaata ataatcctac 3600

 agtttatctt aagaa 3615

<210> 6356
<211> 601
<212> PRT
<213> Homo sapien

<400> 6356
 Met Leu Thr Arg Lys Pro Ser Ala Ala Ala Pro Ala Ala Tyr Pro
   1               5                  10                  15

 Thr Gly Arg Gly Gly Asp Ser Ala Val Arg Gln Leu Gln Ala Ser
                  20                  25                  30

 Pro Gly Leu Gly Ala Gly Pro Thr Arg Ser Gly Val Gly Thr Gly
                  35                  40                  45

 Pro Pro Ser Pro Ile Ala Leu Pro Pro Leu Arg Ala Ser Asn Ala
                  50                  55                  60

 Ala Ala Ala Ala His Thr Ile Gly Gly Ser Lys His Thr Met Asn
                  65                  70                  75

 Asp His Leu His Val Gly Ser His Ala His Gly Gln Ile Gln Val
                  80                  85                  90

 Gln Gln Leu Phe Glu Asp Asn Ser Asn Lys Arg Thr Val Leu Thr
                  95                 100                 105

 Thr Gln Pro Asn Gly Leu Thr Thr Val Gly Lys Thr Gly Leu Pro
                 110                 115                 120

 Val Val Pro Glu Arg Gln Leu Asp Ser Ile His Arg Arg Gln Gly
                 125                 130                 135

 Ser Ser Thr Ser Leu Lys Ser Met Glu Gly Met Gly Lys Val Lys
                 140                 145                 150

 Ala Thr Pro Met Thr Pro Glu Gln Ala Met Lys Gln Tyr Met Gln
                 155                 160                 165

 Lys Leu Thr Ala Phe Glu His His Glu Ile Phe Ser Tyr Pro Glu
                 170                 175                 180

 Ile Tyr Phe Leu Gly Leu Asn Ala Lys Lys Arg Gln Gly Met Thr
                 185                 190                 195

 Gly Gly Pro Asn Asn Gly Gly Tyr Asp Asp Asp Gln Gly Ser Tyr
                 200                 205                 210

 Val Gln Val Pro His Asp His Val Ala Tyr Arg Tyr Glu Val Leu
                 215                 220                 225

 Lys Val Ile Gly Lys Gly Ser Phe Gly Gln Val Val Lys Ala Tyr
                 230                 235                 240

 Asp His Lys Val His Gln His Val Ala Leu Lys Met Val Arg Asn
                 245                 250                 255

 Glu Lys Arg Phe His Arg Gln Ala Ala Glu Glu Ile Arg Ile Leu
                 260                 265                 270

 Glu His Leu Arg Lys Gln Asp Lys Asp Asn Thr Met Asn Val Ile
                 275                 280                 285

 His Met Leu Glu Asn Phe Thr Phe Arg Asn His Ile Cys Met Thr
                 290                 295                 300

 Phe Glu Leu Leu Ser Met Asn Leu Tyr Glu Leu Ile Lys Lys Asn
                 305                 310                 315

 Lys Phe Gln Gly Phe Ser Leu Pro Leu Val Arg Lys Phe Ala His
                 320                 325                 330

 Ser Ile Leu Gln Cys Leu Asp Ala Leu His Lys Asn Arg Ile Ile
                 335                 340                 345

 His Cys Asp Leu Lys Pro Glu Asn Ile Leu Leu Lys Gln Gln Gly
                 350                 355                 360

 Arg Ser Gly Ile Lys Val Ile Asp Phe Gly Ser Ser Cys Tyr Glu
                 365                 370                 375

 His Gln Arg Val Tyr Thr Tyr Ile Gln Ser Arg Phe Tyr Arg Ala
                 380                 385                 390

 Pro Glu Val Ile Leu Gly Ala Arg Tyr Gly Met Pro Ile Asp Met
                 395                 400                 405

 Trp Ser Leu Gly Cys Ile Leu Ala Glu Leu Leu Thr Gly Tyr Pro
                 410                 415                 420

 Leu Leu Pro Gly Glu Asp Glu Gly Asp Gln Leu Ala Cys Met Ile
                 425                 430                 435

 Glu Leu Leu Gly Met Pro Ser Gln Lys Leu Leu Asp Ala Ser Lys
                 440                 445                 450

 Arg Ala Lys Asn Phe Val Ser Ser Lys Gly Tyr Pro Arg Tyr Cys
                 455                 460                 465

 Thr Val Thr Thr Leu Ser Asp Gly Ser Val Val Leu Asn Gly Gly
                 470                 475                 480

 Arg Ser Arg Arg Gly Lys Leu Arg Gly Pro Pro Glu Ser Arg Glu
                 485                 490                 495

 Trp Gly Asn Ala Leu Lys Gly Cys Asp Asp Pro Leu Phe Leu Asp
                 500                 505                 510

 Phe Leu Lys Gln Cys Leu Glu Trp Asp Pro Ala Val Arg Met Thr
                 515                 520                 525

 Pro Gly Gln Ala Leu Arg His Pro Trp Leu Arg Arg Arg Leu Pro
                 530                 535                 540

 Lys Pro Pro Thr Gly Glu Lys Thr Ser Val Lys Arg Ile Thr Glu
                 545                 550                 555

 Ser Thr Gly Ala Ile Thr Ser Ile Ser Lys Leu Pro Pro Pro Ser
                 560                 565                 570

 Ser Ser Ala Ser Lys Leu Arg Thr Asn Leu Ala Gln Met Thr Asp
                 575                 580                 585

 Ala Asn Gly Asn Ile Gln Gln Arg Thr Val Leu Pro Lys Leu Val
                 590                 595                 600

 Ser


<210> 6357
<211> 1488
<212> DNA
<213> Homo sapien

<400> 6357
 gttggtgagc atcatggcaa ccgttacagc cacaaccaaa gtcccggaga 50

 tccgtgatgt aacaaggatt gagcgaatcg gtgcccactc ccacatccgg 100

 ggactggggc tggacgatgc cttggagcct cggcaggctt cgcaaggcat 150

 ggtgggtcag ctggcggcac ggcgggcggc tggcgtggtg ctggagatga 200

 tccgggaagg gaagattgcc ggtcgggcag tccttattgc tggccagccg 250

 ggcacgggga agacggccat cgccatgggc atggcgcagg ccctgggccc 300

 tgacacgcca ttcacagcca tcgccggcag tgaaatcttc tccctggaga 350

 tgagcaagac cgaggcgctg acgcaggcct tccggcggtc catcggcgtt 400

 cgcatcaagg aggagacgga gatcatcgaa ggggaggtgg tggagatcca 450

 gattgatcga ccagcaacag ggacgggctc caaggtgggc aaactgaccc 500

 tcaagaccac agagatggag accatctacg acctgggcac caagatgatt 550

 gagtccctga ccaaggacaa ggtccaggcc ggggacgtga tcaccatcga 600

 caaggcgacg ggcaagatct ccaagctggg ccgctccttc acacgcgccc 650

 gcgactacga cgctatgggc tcccagacca agttcgtgca gtgcccagat 700

 ggggagctcc agaaacgcaa ggaggtggtg cacaccgtgt ccctgcacga 750

 gatcgacgtc atcaactctc gcacccaggg cttcctggcg ctcttctcag 800

 gtgacacagg ggagatcaag tcagaagtcc gtgagcagat caatgccaag 850

 gtggctgagt ggcgcgagga gggcaaggcg gagatcatcc ctggagtgct 900

 gttcatcgac gaggtccaca tgctggacat cgagagcttc tccttcctca 950

 accgggccct ggagagtgac atggcgcctg tcctgatcat ggccaccaac 1000

 cgtggcatca cgcgaatccg gggcaccagc taccagagcc ctcacggcat 1050

 ccccatagac ctgctggacc ggctgcttat cgtctccacc accccctaca 1100

 gcgagaaaga cacgaagcag atcctccgca tccggtgcga ggaagaagat 1150

 gtggagatga gtgaggacgc ctacacggtg ctgacccgca tcgggctgga 1200

 gacgtcactg cgctacgcca tccagctcat cacagctgcc agcttggtgt 1250

 gccggaaacg caagggtaca gaagtgcagg tggatgacat caagcgggtc 1300

 tactcactct tcctggacga gtcccgctcc acgcagtaca tgaaggagta 1350

 ccaggacgcc ttcctcttca acgaactcaa aggcgagacc atggacacct 1400

 cctgagttgg atgtcatccc ccgaccccac cctgttttcc accagagttc 1450

 tgacactgtg actctgtata aaatggttgg gaagctgc 1488

<210> 6358
<211> 463
<212> PRT
<213> Homo sapien

<400> 6358
 Met Ala Thr Val Thr Ala Thr Thr Lys Val Pro Glu Ile Arg Asp
   1               5                  10                  15

 Val Thr Arg Ile Glu Arg Ile Gly Ala His Ser His Ile Arg Gly
                  20                  25                  30

 Leu Gly Leu Asp Asp Ala Leu Glu Pro Arg Gln Ala Ser Gln Gly
                  35                  40                  45

 Met Val Gly Gln Leu Ala Ala Arg Arg Ala Ala Gly Val Val Leu
                  50                  55                  60

 Glu Met Ile Arg Glu Gly Lys Ile Ala Gly Arg Ala Val Leu Ile
                  65                  70                  75

 Ala Gly Gln Pro Gly Thr Gly Lys Thr Ala Ile Ala Met Gly Met
                  80                  85                  90

 Ala Gln Ala Leu Gly Pro Asp Thr Pro Phe Thr Ala Ile Ala Gly
                  95                 100                 105

 Ser Glu Ile Phe Ser Leu Glu Met Ser Lys Thr Glu Ala Leu Thr
                 110                 115                 120

 Gln Ala Phe Arg Arg Ser Ile Gly Val Arg Ile Lys Glu Glu Thr
                 125                 130                 135

 Glu Ile Ile Glu Gly Glu Val Val Glu Ile Gln Ile Asp Arg Pro
                 140                 145                 150

 Ala Thr Gly Thr Gly Ser Lys Val Gly Lys Leu Thr Leu Lys Thr
                 155                 160                 165

 Thr Glu Met Glu Thr Ile Tyr Asp Leu Gly Thr Lys Met Ile Glu
                 170                 175                 180

 Ser Leu Thr Lys Asp Lys Val Gln Ala Gly Asp Val Ile Thr Ile
                 185                 190                 195

 Asp Lys Ala Thr Gly Lys Ile Ser Lys Leu Gly Arg Ser Phe Thr
                 200                 205                 210

 Arg Ala Arg Asp Tyr Asp Ala Met Gly Ser Gln Thr Lys Phe Val
                 215                 220                 225

 Gln Cys Pro Asp Gly Glu Leu Gln Lys Arg Lys Glu Val Val His
                 230                 235                 240

 Thr Val Ser Leu His Glu Ile Asp Val Ile Asn Ser Arg Thr Gln
                 245                 250                 255

 Gly Phe Leu Ala Leu Phe Ser Gly Asp Thr Gly Glu Ile Lys Ser
                 260                 265                 270

 Glu Val Arg Glu Gln Ile Asn Ala Lys Val Ala Glu Trp Arg Glu
                 275                 280                 285

 Glu Gly Lys Ala Glu Ile Ile Pro Gly Val Leu Phe Ile Asp Glu
                 290                 295                 300

 Val His Met Leu Asp Ile Glu Ser Phe Ser Phe Leu Asn Arg Ala
                 305                 310                 315

 Leu Glu Ser Asp Met Ala Pro Val Leu Ile Met Ala Thr Asn Arg
                 320                 325                 330

 Gly Ile Thr Arg Ile Arg Gly Thr Ser Tyr Gln Ser Pro His Gly
                 335                 340                 345

 Ile Pro Ile Asp Leu Leu Asp Arg Leu Leu Ile Val Ser Thr Thr
                 350                 355                 360

 Pro Tyr Ser Glu Lys Asp Thr Lys Gln Ile Leu Arg Ile Arg Cys
                 365                 370                 375

 Glu Glu Glu Asp Val Glu Met Ser Glu Asp Ala Tyr Thr Val Leu
                 380                 385                 390

 Thr Arg Ile Gly Leu Glu Thr Ser Leu Arg Tyr Ala Ile Gln Leu
                 395                 400                 405

 Ile Thr Ala Ala Ser Leu Val Cys Arg Lys Arg Lys Gly Thr Glu
                 410                 415                 420

 Val Gln Val Asp Asp Ile Lys Arg Val Tyr Ser Leu Phe Leu Asp
                 425                 430                 435

 Glu Ser Arg Ser Thr Gln Tyr Met Lys Glu Tyr Gln Asp Ala Phe
                 440                 445                 450

 Leu Phe Asn Glu Leu Lys Gly Glu Thr Met Asp Thr Ser
                 455                 460

<210> 6359
<211> 1025
<212> DNA
<213> Homo sapien

<400> 6359
 ggcacgagtg gcggcagagg cagtgcggat ccggcgttct ccactgatct 50

 tttccaaggc tgtacagaca tggcggcggc ttttcggaag gcggctaagt 100

 cccggcagcg ggaacacaga gagcgaagcg agcctggctt tcgaaaacat 150

 ctgggcctgc tggagaaaaa gaaagattac aaacttcgtg cagatgacta 200

 ccgtaaaaaa caagaatacc tcaaagctct tcggaagaag gctcttgaaa 250

 aaaatccaga tgaattctac tacaaaatga ctcgggttaa actccaggat 300

 ggagtacata ttattaagga gactaaggaa gaagtaaccc cagaacaact 350

 aaagctgatg agaactcagg acgtcaaata tatagaaatg aagagggttg 400

 cagaagctaa gaaaatcgaa agactaaaat cagagctcca tctgctggat 450

 ttccagggga agcaacagaa caagcatgtg ttcttttttg acaccaaaaa 500

 ggaagttgaa cagtttgatg tcgcaactca cctgcaaaca gccccggagc 550

 tagtcgacag agtctttaat aggcccagga tagagacctt gcagaaagaa 600

 aaagtgaaag gagttaccaa tcagactgga cttaagcgaa tagctaaaga 650

 aaggcaaaag cagtataact gcctgacaca gcggattgaa cgagagaaga 700

 aattgttcgt tattgctcag aaaattcaaa cacgcaaaga tcttatggat 750

 aaaactcaga aagtgaaggt gaagaaagaa acggtgaact ccccagctat 800

 ttataaattt cagagtcgtc gaaaacgttg acgtgttata gataagcctt 850

 gtcattctgt atcaaaaatc tgttgtcgtt ttctagtaac ttcaaattcc 900

 attactccaa atggcatggt tttccggttt gtaaccataa ctaaattgtc 950

 agtctgacat ttaatgtctt tctatggaca acattaaatc tccctccctt 1000

 ctgtaattgt ttttggattg tgaaa 1025

<210> 6360
<211> 253
<212> PRT
<213> Homo sapien

<400> 6360
 Met Ala Ala Ala Phe Arg Lys Ala Ala Lys Ser Arg Gln Arg Glu
   1               5                  10                  15

 His Arg Glu Arg Ser Glu Pro Gly Phe Arg Lys His Leu Gly Leu
                  20                  25                  30

 Leu Glu Lys Lys Lys Asp Tyr Lys Leu Arg Ala Asp Asp Tyr Arg
                  35                  40                  45

 Lys Lys Gln Glu Tyr Leu Lys Ala Leu Arg Lys Lys Ala Leu Glu
                  50                  55                  60

 Lys Asn Pro Asp Glu Phe Tyr Tyr Lys Met Thr Arg Val Lys Leu
                  65                  70                  75

 Gln Asp Gly Val His Ile Ile Lys Glu Thr Lys Glu Glu Val Thr
                  80                  85                  90

 Pro Glu Gln Leu Lys Leu Met Arg Thr Gln Asp Val Lys Tyr Ile
                  95                 100                 105

 Glu Met Lys Arg Val Ala Glu Ala Lys Lys Ile Glu Arg Leu Lys
                 110                 115                 120

 Ser Glu Leu His Leu Leu Asp Phe Gln Gly Lys Gln Gln Asn Lys
                 125                 130                 135

 His Val Phe Phe Phe Asp Thr Lys Lys Glu Val Glu Gln Phe Asp
                 140                 145                 150

 Val Ala Thr His Leu Gln Thr Ala Pro Glu Leu Val Asp Arg Val
                 155                 160                 165

 Phe Asn Arg Pro Arg Ile Glu Thr Leu Gln Lys Glu Lys Val Lys
                 170                 175                 180

 Gly Val Thr Asn Gln Thr Gly Leu Lys Arg Ile Ala Lys Glu Arg
                 185                 190                 195

 Gln Lys Gln Tyr Asn Cys Leu Thr Gln Arg Ile Glu Arg Glu Lys
                 200                 205                 210

 Lys Leu Phe Val Ile Ala Gln Lys Ile Gln Thr Arg Lys Asp Leu
                 215                 220                 225

 Met Asp Lys Thr Gln Lys Val Lys Val Lys Lys Glu Thr Val Asn
                 230                 235                 240

 Ser Pro Ala Ile Tyr Lys Phe Gln Ser Arg Arg Lys Arg
                 245                 250

<210> 6361
<211> 1938
<212> DNA
<213> Homo sapien

<400> 6361
 attccggttg ttgcaccatg gcgtccatgg ggaccctcgc cttcgatgaa 50

 tatgggcgcc ctttcctcat catcaaggat caggaccgca agtcccgtct 100

 tatgggactt gaggccctca agtctcatat aatggcagca aaggctgtag 150

 caaatacaat gagaacatca cttggaccaa atgggcttga taagatgatg 200

 gtggataagg atggagatgt gactgtaact aatgatgggg ccaccatctt 250

 aagcatgatg gatgttgatc atcagattgc caagctgatg gtggaactgt 300

 ccaagtctca ggatgatgaa attggagatg gaaccacagg agtggttgtc 350

 ctggctggtg ccttgttaga agaagcggag caattgctag accgaggcat 400

 tcacccaatc agaatagccg atggctatga gcaggctgct cgtgttgcta 450

 ttgaacacct ggacaagatc agcgatagcg tccttgttga cataaaggac 500

 accgaacccc tgattcagac agcaaaaacc acgctgggct ccaaagtggt 550

 caacagttgt caccgacaga tggctgagat tgctgtgaat gccgtcctca 600

 ctgtagcaga tatggagcgg agagacgttg actttgagct tatcaaagta 650

 gaaggcaaag tgggcggcag gctggaggac actaaactga ttaagggcgt 700

 gattgtggac aaggatttca gtcacccaca gatgccaaaa aaagtggaag 750

 atgcgaagat tgcaattctc acatgtccat ttgaaccacc caaaccaaaa 800

 acaaagcata agctggatgt gacctctgtc gaagattata aagcccttca 850

 gaaatacgaa aaggagaaat ttgaagagat gattcaacaa attaaagaga 900

 ctggtgctaa cctagcaatt tgtcagtggg gctttgatga tgaagcaaat 950

 cacttacttc ttcagaacaa cttgcctgcg gttcgctggg taggaggacc 1000

 tgaaattgag ctgattgcca tcgcaacagg agggcggatc gtccccaggt 1050

 tctcagagct cacagccgag aagctgggct ttgctggtct tgtacaggag 1100

 atctcatttg ggacaactaa ggataaaatg ctggtcatcg agcagtgtaa 1150

 gaactccaga gctgtaacca tttttattag aggaggaaat aagatgatca 1200

 ttgaggaggc gaaacgatcc cttcacgatg ctttgtgtgt catccggaac 1250

 ctcatccgcg ataatcgtgt ggtgtatgga ggaggggctg ctgagatatc 1300

 ctgtgccctg gcagttagcc aagaggcgga taagtgcccc accttagaac 1350

 agtatgccat gagagcgttt gccgacgcac tggaggtcat ccccatggcc 1400

 ctctctgaaa acagtggcat gaatcccatc cagactatga ccgaagtccg 1450

 agccagacag gtgaaggaga tgaaccctgc tcttggcatc gactgtttgc 1500

 acaaggggac aaatgatatg aagcaacagc atgtcataga aaccttgatt 1550

 ggcaaaaagc aacagatatc tcttgcaaca caaatggtta gaatgatttt 1600

 gaagattgat gacattcgta agcctggaga atctgaagaa tgaagacatt 1650

 gagaaaacta tgtagcaaga tccacttctg tgattaagta aatggatgtc 1700

 tcgtgatgca tctacagtta tttattgtta catccttttc cagacactgt 1750

 agatgctata ataaaaatag ctgtttggta accatagttt cacttgttca 1800

 aagctgtgta atcgtggggg taccatctca actgcttttg tattcattgt 1850

 attaaaagaa tctgtttaaa caacctttat cttctcttcg ggtttaagaa 1900

 acgtttattg taacagtaat taaatgctgc cttaattg 1938

<210> 6362
<211> 2391
<212> DNA
<213> Homo sapien

<400> 6362
 tgcggccgca cctgcaggcg cagagtaggt atggaagatc cctcgagatc 50

 cattgtgctc taaagccgcc gggggtccgt gtcctgtctc ggttggccgg 100

 acccgggccc gagcccgagc agtagccggc gccatgtcgg tggtgggcat 150

 agacctgggc ttccagagct gctacgtcgc tgtggcccgc gccggcggca 200

 tcgagactat cgctaatgag tatagcgacc gctgcacgcc ggcttgcatt 250

 tcttttggtc ctaagaatcg ttcaattgga gcagcagcta aaagccaggt 300

 aatttctaat gcaaagaaca cagtccaagg atttaaaaga ttccatggcc 350

 gagcattctc tgatccattt gtggaggcag aaaaatctaa ccttgcatat 400

 gatattgtgc agtggcctac aggattaaca ggtataaagg tgacatatat 450

 ggaggaagag cgaaatttta ccactgagca agtgactgcc atgcttttgt 500

 ccaaactgaa ggagacagcc gaaagtgttc ttaagaagcc tgtagttgac 550

 tgtgttgttt cggttccttg tttctatact gatgcagaaa gacgatcagt 600

 gatggatgca acacagattg ctggtcttaa ttgcttgcga ttaatgaatg 650

 aaaccactgc agttgctctt gcatatggaa tctataagca ggatcttcct 700

 cgcttagaag agaaaccaag aaatgtagtt tttgtagaca tgggccactc 750

 tgcttatcaa gtttctgtat gtgcatttaa tagaggaaaa ctgaaagttc 800

 tggccactgc atttgacacg acattgggag gtagaaaatt tgatgaagtg 850

 ttagtaaatc acttctgtga agaatttggg aagaaataca agctagacat 900

 taagtccaaa atccgtgcat tattacgact ctctcaggag tgtgagaaac 950

 tcaagaaatt gatgagtgca aatgcttcag atctcccttt gagcattgaa 1000

 tgttttatga atgatgttga tgtatctgga actatgaata gaggcaaatt 1050

 tctggagatg tgcaatgatc tcttagctag agtggagcca ccacttcgta 1100

 gtgttttgga acaaaccaag ttaaagaaag aagatattta tgcagtggag 1150

 atagttggtg gtgctacacg aatccctgcg gtaaaagaga agatcagcaa 1200

 atttttcggt aaagaactta gtacaacatt aaatgctgat gaagctgtca 1250

 ctcgaggctg tgcattgcag tgtgccatct tatcgcctgc tttcaaagtc 1300

 agagaatttt ctatcactga tgtagtacca tatccaatat ctctgagatg 1350

 gaattctcca gctgaagaag ggtcaagtga ctgtgaagtc ttttccaaaa 1400

 atcatgctgc tcctttctct aaagttctta cattttatag aaaggaacct 1450

 ttcactcttg aggcctacta cagctctcct caggatttgc cctatccaga 1500

 tcctgctata gctcagtttt cagttcagaa agtcactcct cagtctgatg 1550

 gctccagttc aaaagtgaaa gtcaaagttc gagtaaatgt ccatggcatt 1600

 ttcagtgtgt ccagtgcatc tttagtggag gttcacaagt ctgaggaaaa 1650

 tgaggagcca atggaaacag atcagaatgc aaaggaggaa gagaagatgc 1700

 aagtggacca ggaggaacca catgttgaag agcaacagca gcagacacca 1750

 gcagaaaata aggcagagtc tgaagaaatg gagacctctc aagctggatc 1800

 caaggataaa aagatggacc aaccacccca atgccaagaa ggcaaaagtg 1850

 aagaccagta ctgtggacct gccaatcgag aatcagctat atggcagata 1900

 gacagagaga tgctcaactt gtacattgaa aatgagggta agatgatcat 1950

 gcaggataaa ctggagaagg agcggaatga tgctaagaac gcagtggagg 2000

 aatatgtgta tgaaatgaga gacaagctta gtggtgaata tgagaagttt 2050

 gtgagtgaag atgatcgtaa cagttttact ttgaaactgg aagatactga 2100

 aaattggttg tatgaggatg gagaagacca gccaaagcaa gtttatgttg 2150

 ataagttggc tgaattaaaa aatctaggtc aacctattaa gatacgtttc 2200

 caggaatctg aagaacgacc aaattatttg aagaactaga gaacttaggg 2250

 aaacagatcc aacagtatat gaaaataatc agctcctttc aaaaacaagg 2300

 aggaccaggt atgatcattt ggatgctgct gacatgacaa aggtagaaaa 2350

 aagcacaaat gaagcaatgg agtggatgga agtcacacca a 2391

<210> 6363
<211> 701
<212> PRT
<213> Homo sapien

<400> 6363
 Met Ser Val Val Gly Ile Asp Leu Gly Phe Gln Ser Cys Tyr Val
   1               5                  10                  15

 Ala Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Tyr
                  20                  25                  30

 Ser Asp Arg Cys Thr Pro Ala Cys Ile Ser Phe Gly Pro Lys Asn
                  35                  40                  45

 Arg Ser Ile Gly Ala Ala Ala Lys Ser Gln Val Ile Ser Asn Ala
                  50                  55                  60

 Lys Asn Thr Val Gln Gly Phe Lys Arg Phe His Gly Arg Ala Phe
                  65                  70                  75

 Ser Asp Pro Phe Val Glu Ala Glu Lys Ser Asn Leu Ala Tyr Asp
                  80                  85                  90

 Ile Val Gln Trp Pro Thr Gly Leu Thr Gly Ile Lys Val Thr Tyr
                  95                 100                 105

 Met Glu Glu Glu Arg Asn Phe Thr Thr Glu Gln Val Thr Ala Met
                 110                 115                 120

 Leu Leu Ser Lys Leu Lys Glu Thr Ala Glu Ser Val Leu Lys Lys
                 125                 130                 135

 Pro Val Val Asp Cys Val Val Ser Val Pro Cys Phe Tyr Thr Asp
                 140                 145                 150

 Ala Glu Arg Arg Ser Val Met Asp Ala Thr Gln Ile Ala Gly Leu
                 155                 160                 165

 Asn Cys Leu Arg Leu Met Asn Glu Thr Thr Ala Val Ala Leu Ala
                 170                 175                 180

 Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Arg Leu Glu Glu Lys Pro
                 185                 190                 195

 Arg Asn Val Val Phe Val Asp Met Gly His Ser Ala Tyr Gln Val
                 200                 205                 210

 Ser Val Cys Ala Phe Asn Arg Gly Lys Leu Lys Val Leu Ala Thr
                 215                 220                 225

 Ala Phe Asp Thr Thr Leu Gly Gly Arg Lys Phe Asp Glu Val Leu
                 230                 235                 240

 Val Asn His Phe Cys Glu Glu Phe Gly Lys Lys Tyr Lys Leu Asp
                 245                 250                 255

 Ile Lys Ser Lys Ile Arg Ala Leu Leu Arg Leu Ser Gln Glu Cys
                 260                 265                 270

 Glu Lys Leu Lys Lys Leu Met Ser Ala Asn Ala Ser Asp Leu Pro
                 275                 280                 285

 Leu Ser Ile Glu Cys Phe Met Asn Asp Val Asp Val Ser Gly Thr
                 290                 295                 300

 Met Asn Arg Gly Lys Phe Leu Glu Met Cys Asn Asp Leu Leu Ala
                 305                 310                 315

 Arg Val Glu Pro Pro Leu Arg Ser Val Leu Glu Gln Thr Lys Leu
                 320                 325                 330

 Lys Lys Glu Asp Ile Tyr Ala Val Glu Ile Val Gly Gly Ala Thr
                 335                 340                 345

 Arg Ile Pro Ala Val Lys Glu Lys Ile Ser Lys Phe Phe Gly Lys
                 350                 355                 360

 Glu Leu Ser Thr Thr Leu Asn Ala Asp Glu Ala Val Thr Arg Gly
                 365                 370                 375

 Cys Ala Leu Gln Cys Ala Ile Leu Ser Pro Ala Phe Lys Val Arg
                 380                 385                 390

 Glu Phe Ser Ile Thr Asp Val Val Pro Tyr Pro Ile Ser Leu Arg
                 395                 400                 405

 Trp Asn Ser Pro Ala Glu Glu Gly Ser Ser Asp Cys Glu Val Phe
                 410                 415                 420

 Ser Lys Asn His Ala Ala Pro Phe Ser Lys Val Leu Thr Phe Tyr
                 425                 430                 435

 Arg Lys Glu Pro Phe Thr Leu Glu Ala Tyr Tyr Ser Ser Pro Gln
                 440                 445                 450

 Asp Leu Pro Tyr Pro Asp Pro Ala Ile Ala Gln Phe Ser Val Gln
                 455                 460                 465

 Lys Val Thr Pro Gln Ser Asp Gly Ser Ser Ser Lys Val Lys Val
                 470                 475                 480

 Lys Val Arg Val Asn Val His Gly Ile Phe Ser Val Ser Ser Ala
                 485                 490                 495

 Ser Leu Val Glu Val His Lys Ser Glu Glu Asn Glu Glu Pro Met
                 500                 505                 510

 Glu Thr Asp Gln Asn Ala Lys Glu Glu Glu Lys Met Gln Val Asp
                 515                 520                 525

 Gln Glu Glu Pro His Val Glu Glu Gln Gln Gln Gln Thr Pro Ala
                 530                 535                 540

 Glu Asn Lys Ala Glu Ser Glu Glu Met Glu Thr Ser Gln Ala Gly
                 545                 550                 555

 Ser Lys Asp Lys Lys Met Asp Gln Pro Pro Gln Cys Gln Glu Gly
                 560                 565                 570

 Lys Ser Glu Asp Gln Tyr Cys Gly Pro Ala Asn Arg Glu Ser Ala
                 575                 580                 585

 Ile Trp Gln Ile Asp Arg Glu Met Leu Asn Leu Tyr Ile Glu Asn
                 590                 595                 600

 Glu Gly Lys Met Ile Met Gln Asp Lys Leu Glu Lys Glu Arg Asn
                 605                 610                 615

 Asp Ala Lys Asn Ala Val Glu Glu Tyr Val Tyr Glu Met Arg Asp
                 620                 625                 630

 Lys Leu Ser Gly Glu Tyr Glu Lys Phe Val Ser Glu Asp Asp Arg
                 635                 640                 645

 Asn Ser Phe Thr Leu Lys Leu Glu Asp Thr Glu Asn Trp Leu Tyr
                 650                 655                 660

 Glu Asp Gly Glu Asp Gln Pro Lys Gln Val Tyr Val Asp Lys Leu
                 665                 670                 675

 Ala Glu Leu Lys Asn Leu Gly Gln Pro Ile Lys Ile Arg Phe Gln
                 680                 685                 690

 Glu Ser Glu Glu Arg Pro Asn Tyr Leu Lys Asn
                 695                 700

<210> 6364
<211> 2365
<212> DNA
<213> Homo sapien

<400> 6364
 tcccagcctt cccatccccc caccgaaagc aaatcattca acgacccccg 50

 accctccgac ggcaggagcc ccccgacctc ccaggcggac cgcccttccc 100

 tccccgcgcg ggttccgggc ccggcgagag ggcgcgacga cagccgaggc 150

 catggaggtg acggcggacc agccgcgctg ggtgagccac caccaccccg 200

 ccgtgctcaa cgggcagcac ccggacacgc accacccggg cctcagccac 250

 tcctacatgg acgcggcgca gtacccgctg ccggaggagg tggatgtgct 300

 ttttaacatc gacggtcaag gcaaccacgt cccgccctac tacggaaact 350

 cggtcagggc cacggtgcag aggtaccctc cgacccacca cgggagccag 400

 gtgtgccgcc cgcctctgct tcatggatcc ctaccctggc tggacggcgg 450

 caaagccctg ggcagccacc acaccgcctc cccctggaat ctcagcccct 500

 tctccaagac gtccatccac cacggctccc cggggcccct ctccgtctac 550

 cccccggcct cgtcctcctc cttgtcgggg ggccacgcca gcccgcacct 600

 cttcaccttc ccgcccaccc cgccgaagga cgtctccccg gacccatcgc 650

 tgtccacccc aggctcggcc ggctcggccc ggcaggacga gaaagagtgc 700

 ctcaagtacc aggtgcccct gcccgacagc atgaagctgg agtcgtccca 750

 ctcccgtggc agcatgaccg ccctgggtgg agcctcctcg tcgacccacc 800

 accccatcac cacctacccg ccctacgtgc ccgagtacag ctccggactc 850

 ttccccccca gcagcctgct gggcggctcc cccaccggct tcggatgcaa 900

 gtccaggccc aaggcccggt ccagcacagg cagggagtgt gtgaactgtg 950

 gggcaacctc gaccccactg tggcggcgag atggcacggg acactacctg 1000

 tgcaacgcct gcgggctcta tcacaaaatg aacggacaga accggcccct 1050

 cattaagccc aagcgaaggc tgtctgcagc caggagagca gggacgtcct 1100

 gtgcgaactg tcagaccacc acaaccacac tctggaggag gaatgccaat 1150

 ggggaccctg tctgcaatgc ctgtgggctc tactacaagc ttcacaatat 1200

 taacagaccc ctgactatga agaaggaagg catccagacc agaaaccgaa 1250

 aaatgtctag caaatccaaa aagtgcaaaa aagtgcatga ctcactggag 1300

 gacttcccca agaacagctc gtttaacccg gccgccctct ccagacacat 1350

 gtcctccctg agccacatct cgcccttcag ccactccagc cacatgctga 1400

 ccacgcccac gccgatgcac ccgccatcca gcctgtcctt tggaccacac 1450

 cacccctcca gcatggtcac cgccatgggt tagagccctg ctcgatgctc 1500

 acagggcccc cagcgagagt ccctgcagtc cctttcgact tgcatttttg 1550

 caggagcagt atcatgaagc ctaaacgcga tggatatatg tttttgaagg 1600

 cagaaagcaa aattatgttt gccactttgc aaaggagctc actgtggtgt 1650

 ctgtgttcca accactgaat ctggacccca tctgtgaata agccattctg 1700

 actcatatcc cctatttaac agggtctcta gtgctgtgaa aaaaaaaaat 1750

 cctgaacatt gcatataact tatattgtaa gaaatactgt acaatgactt 1800

 tattgcatct gggtagctgt aaggcatgaa ggatgccaag aagtttaagg 1850

 aatatgggag aaatagtgtg gaaattaaga agaaactagg tctgatattc 1900

 aaatggacaa actgccagtt ttgtttcctt tcactggcca cagttgtttg 1950

 atgcattaaa agaaaataaa aaaaagaaaa aagagaaaag aaaaaaaaag 2000

 aaaaaagttg taggcgaatc atttgttcaa agctgttggc cctctgcaaa 2050

 ggaaatacca gttctgggca atcagtgtta ccgttcacca gttgccattg 2100

 agggtttcag agagcctttt tctaggccta catgctttgt gaacaagtcc 2150

 ctgtaattgt tgtttgtatg tataattcaa agcaccaaaa taagaaaaga 2200

 tgtagattta tttcatcata ttatacagac cgaactgttg tataaattta 2250

 tttactgcta gtcttaagaa ctgctttctt tcgtttgttt gtttcaatat 2300

 tttccttctc tctcaatttt cggttgaata aactagatta cattcagttg 2350

 gcaaaaaaaa aaaaa 2365

<210> 6365
<211> 443
<212> PRT
<213> Homo sapien

<400> 6365
 Met Glu Val Thr Ala Asp Gln Pro Arg Trp Val Ser His His His
   1               5                  10                  15

 Pro Ala Val Leu Asn Gly Gln His Pro Asp Thr His His Pro Gly
                  20                  25                  30

 Leu Ser His Ser Tyr Met Asp Ala Ala Gln Tyr Pro Leu Pro Glu
                  35                  40                  45

 Glu Val Asp Val Leu Phe Asn Ile Asp Gly Gln Gly Asn His Val
                  50                  55                  60

 Pro Pro Tyr Tyr Gly Asn Ser Val Arg Ala Thr Val Gln Arg Tyr
                  65                  70                  75

 Pro Pro Thr His His Gly Ser Gln Val Cys Arg Pro Pro Leu Leu
                  80                  85                  90

 His Gly Ser Leu Pro Trp Leu Asp Gly Gly Lys Ala Leu Gly Ser
                  95                 100                 105

 His His Thr Ala Ser Pro Trp Asn Leu Ser Pro Phe Ser Lys Thr
                 110                 115                 120

 Ser Ile His His Gly Ser Pro Gly Pro Leu Ser Val Tyr Pro Pro
                 125                 130                 135

 Ala Ser Ser Ser Ser Leu Ser Gly Gly His Ala Ser Pro His Leu
                 140                 145                 150

 Phe Thr Phe Pro Pro Thr Pro Pro Lys Asp Val Ser Pro Asp Pro
                 155                 160                 165

 Ser Leu Ser Thr Pro Gly Ser Ala Gly Ser Ala Arg Gln Asp Glu
                 170                 175                 180

 Lys Glu Cys Leu Lys Tyr Gln Val Pro Leu Pro Asp Ser Met Lys
                 185                 190                 195

 Leu Glu Ser Ser His Ser Arg Gly Ser Met Thr Ala Leu Gly Gly
                 200                 205                 210

 Ala Ser Ser Ser Thr His His Pro Ile Thr Thr Tyr Pro Pro Tyr
                 215                 220                 225

 Val Pro Glu Tyr Ser Ser Gly Leu Phe Pro Pro Ser Ser Leu Leu
                 230                 235                 240

 Gly Gly Ser Pro Thr Gly Phe Gly Cys Lys Ser Arg Pro Lys Ala
                 245                 250                 255

 Arg Ser Ser Thr Gly Arg Glu Cys Val Asn Cys Gly Ala Thr Ser
                 260                 265                 270

 Thr Pro Leu Trp Arg Arg Asp Gly Thr Gly His Tyr Leu Cys Asn
                 275                 280                 285

 Ala Cys Gly Leu Tyr His Lys Met Asn Gly Gln Asn Arg Pro Leu
                 290                 295                 300

 Ile Lys Pro Lys Arg Arg Leu Ser Ala Ala Arg Arg Ala Gly Thr
                 305                 310                 315

 Ser Cys Ala Asn Cys Gln Thr Thr Thr Thr Thr Leu Trp Arg Arg
                 320                 325                 330

 Asn Ala Asn Gly Asp Pro Val Cys Asn Ala Cys Gly Leu Tyr Tyr
                 335                 340                 345

 Lys Leu His Asn Ile Asn Arg Pro Leu Thr Met Lys Lys Glu Gly
                 350                 355                 360

 Ile Gln Thr Arg Asn Arg Lys Met Ser Ser Lys Ser Lys Lys Cys
                 365                 370                 375

 Lys Lys Val His Asp Ser Leu Glu Asp Phe Pro Lys Asn Ser Ser
                 380                 385                 390

 Phe Asn Pro Ala Ala Leu Ser Arg His Met Ser Ser Leu Ser His
                 395                 400                 405

 Ile Ser Pro Phe Ser His Ser Ser His Met Leu Thr Thr Pro Thr
                 410                 415                 420

 Pro Met His Pro Pro Ser Ser Leu Ser Phe Gly Pro His His Pro
                 425                 430                 435

 Ser Ser Met Val Thr Ala Met Gly
                 440

<210> 6366
<211> 2945
<212> DNA
<213> Homo sapien

<400> 6366
 ccagcccccc ttcccttccc tgaccccttc ttgccatcgc cccagacatg 50

 gggaacgcgg cgaccgccaa gaaaggcagc gaggtggaga gcgtgaaaga 100

 gtttctagcc aaagccaaag aagacttttt gaaaaaatgg gagaatccaa 150

 ctcagaataa tgccggactt gaagattttg aaaggaaaaa aacccttgga 200

 acaggttcat ttggaagagt catgttggta aaacacaaag ccactgaaca 250

 gtattatgcc atgaagatct tagataagca gaaggttgtt aaactgaagc 300

 aaatagagca tactttgaat gagaaaagaa tattacaggc agtgaatttt 350

 cctttccttg ttcgactgga gtatgctttt aaggataatt ctaatttata 400

 catggttatg gaatatgtcc ctgggggtga aatgttttca catctaagaa 450

 gaattggaag gttcagtgag ccccatgcac ggttctatgc agctcagata 500

 gtgctaacat tcgagtacct ccattcacta gacctcatct acagagatct 550

 aaaacctgaa aatctcttaa ttgaccatca aggctatatc caggtcacag 600

 actttgggtt tgccaaaaga gttaaaggca gaacttggac attatgtgga 650

 actccagagt atttggctcc agaaataatt ctcagcaagg gctacaataa 700

 ggcagtggat tggtgggcat taggagtgct aatctatgaa atggcagctg 750

 gctatccccc attctttgca gaccaaccaa ttcagattta tgaaaagatt 800

 gtttctggaa aggtccgatt cccatcccac ttcagttcag atctcaagga 850

 ccttctacgg aacctgctgc aggtggattt gaccaagaga tttggaaatc 900

 taaagaatgg tgtcagtgat ataaaaactc acaagtggtt tgccacgaca 950

 gattggattg ctatttacca gaggaaggtt gaagctccat tcataccaaa 1000

 gtttagaggc tctggagata ccagcaactt tgatgactat gaagaagaag 1050

 atatccgtgt ctctataaca gaaaaatgtg caaaagaatt tggtgaattt 1100

 taaagaggaa caagatgaca tctgagctca cactcagtgt ttgcactctg 1150

 ttgagagata aggtagagct gagaccgtcc ttgttgaagc agttacctag 1200

 ttccttcatt ccaacgactg agtgaggtct ttattgccat catccgtgtg 1250

 cgcactctgc atccacctat gtaacaaggc accgctaagc aagcattgtc 1300

 tgtgccataa cacagtacta gaccactttc ttacttctct ttgggttgtc 1350

 tttctcctct cctacatcca tttcttcctt ttcaatttca ttggttttct 1400

 ctaaacagtg ctccatttta ttttgttggt gtttcagatg ggcagtgtta 1450

 tggctacgtg atatttgaag ggaaggataa gtgttgcttt cagtagttat 1500

 tgccaatatt gttgttggtc aatggcttga agataaactt tctaataatt 1550

 attatttctt tgagtagctc agacttggtt ttgccaaaac tcttggtaat 1600

 ttttgaagat agactgtctt atcaccaagg aaatttatac aaattaagac 1650

 taactttctt ggaattcact attctggcaa taaattttgg tagactaata 1700

 cagtacagct agacccagaa atttggaagg ctgtagatca gaggttctag 1750

 ttccctttcc ctccttttat atcctcctct ccttgagtaa tgaagtgacc 1800

 agcctgtgta gtgtgacaaa cgtgtctcat tcagcaggaa aaactaatga 1850

 tatggatcat cacccagatt ctctcacttg gtaccagcat ttctgtaggt 1900

 attagagaag agttctaagt tttctaaacc ttaactgttc cttaaggatt 1950

 ttagccagta ttttaataga acatgattaa tgaaagtgac aaattttaaa 2000

 ttttctctaa tagtcctcat cataaacttt ttaaaggaaa ataagcaaac 2050

 taaaaagaac attggtttag ataaatactt atactttgca aagtcaaaaa 2100

 tggcttgatt tttggaaaca atatagaggt attcatattt aaatgagggt 2150

 ttacatttgt tttgttttgt aaccgttaaa aagaagttgt ttccagctaa 2200

 ttattgtggt gtactatatt tgtgagccta gggtaggggc actgctgcaa 2250

 cttctgcttt catcccatgc ctcatcaatg aggaaaggga acaaagtgta 2300

 taaaacctgc cacaattgta ttttaatttt gaggtatgat attttcagat 2350

 atttcataat ttctaacctc tgttctctca gtaaacagaa tgtctgatcg 2400

 atcatgcaga tacaatgttg gtatttgaga ggttagtttt tttcctacac 2450

 ttttttttgc caactgactt aacaacattg ctgtcaggtg gaaatttcaa 2500

 gcacttttgc acatttagtt cagtgtttgt tgagaatcca tggcttaacc 2550

 cacttgtttt gctatttttt tctttgcttt taattttccc catctgattt 2600

 tatctctgcg tttcagtgac ctaccttaaa acaacacacg agaagagtta 2650

 aactgggttc attttaatga tcaatttacc tgcatataaa atttattttt 2700

 aatcaagctg atcttaatgt atataatcat tctatttgct ttattatcgg 2750

 tgcaggtagg tcattaacac cacttctttt catctgtacc acaccctggt 2800

 gaaacctttg aagacataaa aaaaacctgt ctgagatgtt ctttctacca 2850

 atctatatgt ctttcggtta tcaagtgttt ctgcatggta atgtcatgta 2900

 aatgctgata ttgatttcac tggtccatct atatttaaaa cgtgc 2945

<210> 6367
<211> 351
<212> PRT
<213> Homo sapien

<400> 6367
 Met Gly Asn Ala Ala Thr Ala Lys Lys Gly Ser Glu Val Glu Ser
   1               5                  10                  15

 Val Lys Glu Phe Leu Ala Lys Ala Lys Glu Asp Phe Leu Lys Lys
                  20                  25                  30

 Trp Glu Asn Pro Thr Gln Asn Asn Ala Gly Leu Glu Asp Phe Glu
                  35                  40                  45

 Arg Lys Lys Thr Leu Gly Thr Gly Ser Phe Gly Arg Val Met Leu
                  50                  55                  60

 Val Lys His Lys Ala Thr Glu Gln Tyr Tyr Ala Met Lys Ile Leu
                  65                  70                  75

 Asp Lys Gln Lys Val Val Lys Leu Lys Gln Ile Glu His Thr Leu
                  80                  85                  90

 Asn Glu Lys Arg Ile Leu Gln Ala Val Asn Phe Pro Phe Leu Val
                  95                 100                 105

 Arg Leu Glu Tyr Ala Phe Lys Asp Asn Ser Asn Leu Tyr Met Val
                 110                 115                 120

 Met Glu Tyr Val Pro Gly Gly Glu Met Phe Ser His Leu Arg Arg
                 125                 130                 135

 Ile Gly Arg Phe Ser Glu Pro His Ala Arg Phe Tyr Ala Ala Gln
                 140                 145                 150

 Ile Val Leu Thr Phe Glu Tyr Leu His Ser Leu Asp Leu Ile Tyr
                 155                 160                 165

 Arg Asp Leu Lys Pro Glu Asn Leu Leu Ile Asp His Gln Gly Tyr
                 170                 175                 180

 Ile Gln Val Thr Asp Phe Gly Phe Ala Lys Arg Val Lys Gly Arg
                 185                 190                 195

 Thr Trp Thr Leu Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Ile
                 200                 205                 210

 Ile Leu Ser Lys Gly Tyr Asn Lys Ala Val Asp Trp Trp Ala Leu
                 215                 220                 225

 Gly Val Leu Ile Tyr Glu Met Ala Ala Gly Tyr Pro Pro Phe Phe
                 230                 235                 240

 Ala Asp Gln Pro Ile Gln Ile Tyr Glu Lys Ile Val Ser Gly Lys
                 245                 250                 255

 Val Arg Phe Pro Ser His Phe Ser Ser Asp Leu Lys Asp Leu Leu
                 260                 265                 270

 Arg Asn Leu Leu Gln Val Asp Leu Thr Lys Arg Phe Gly Asn Leu
                 275                 280                 285

 Lys Asn Gly Val Ser Asp Ile Lys Thr His Lys Trp Phe Ala Thr
                 290                 295                 300

 Thr Asp Trp Ile Ala Ile Tyr Gln Arg Lys Val Glu Ala Pro Phe
                 305                 310                 315

 Ile Pro Lys Phe Arg Gly Ser Gly Asp Thr Ser Asn Phe Asp Asp
                 320                 325                 330

 Tyr Glu Glu Glu Asp Ile Arg Val Ser Ile Thr Glu Lys Cys Ala
                 335                 340                 345

 Lys Glu Phe Gly Glu Phe
                 350

<210> 6368
<211> 6381
<212> DNA
<213> Homo sapien

<400> 6368
 cgcggccgct atatataatg cagcatcaca ccatgtaggg catttactct 50

 tattttatac attcagatat gtttgaaaca ttcttaaggc tacaaaacag 100

 aacatagaaa aataaacagg aatatattca acacttacaa aaagtgatat 150

 gataaagaat ataaagtact agtttccttt taacacttca aaagatatgt 200

 atatatactt ttttttacaa gtaacatcac aaatgctcac atcttcacat 250

 gctcttaaag tattatttgt actcagtgta aggctattat cgtttttcat 300

 acataaaatt ttctagctct gtaacacaat gcaattttta atccattcag 350

 taagttcaac cccaaagttg ccgcttccca gcattaagac atgcacccac 400

 ccctcttcta agattttcta aacttgtatt tcggggagaa agacctcttt 450

 taaaaaataa tccaattagt gggagagtaa atggctgaca ttagtagcaa 500

 aaccttagtt atctgaaaat aacatattgg aaatgagaca ttattaggat 550

 tttaaacaaa caatagcatt tagacataaa gtaggaagca aaatacagta 600

 aacagaaata gtgtagccaa atatcattct cttcagctac cttaagtaaa 650

 agacaaaaca tttacctcat ctaaaaatga aggtaaaacg aaagaggcaa 700

 aaataaatat tgctagtttc taggatggct gaatgttttc taaaccagaa 750

 atggttagaa aggaacttta ttgcaccaag tcaatcataa gcaagtttgc 800

 agttcacagg cattttaatt caaccttgag tcacaaagga gaacaacacg 850

 ctgcgagaat acagtctaca gtctgcatta aataagaata tatcagcatt 900

 gtggtctggg aaaacctatg cttgccagga caaggcaggg tgctgagctt 950

 aggtcatgcc atgaaaatga atttgtgggt tatcagtaaa cagtatgagg 1000

 actacacaga tgccagcatc ctgctgccaa ggagacatgg ggcaagagtt 1050

 gaagatttga gaggaaatga agagacatac acaacaccaa aggaaaaggg 1100

 ggctggaatc aagttcagcc aaagcaccta acacaaaaaa caggtgagct 1150

 ttggtcagtc tgttcttcaa aatatgtatg atcatatggt aatgaagttt 1200

 cataatttcc aactcaaaaa tacaaatgat cctcagttct atacttttgc 1250

 ctctattctc ttataaagaa atatgtcaac ataacagtat gacataacag 1300

 ttaaaataag gacaaaagct tgcttatctt agtttgacct cagcataagg 1350

 caaaatcccc tggagaatac atttaaaaac aaacttaaaa ggaaaaaaag 1400

 cgaaaccaac ttcatgcaaa gattcctttt aaaactatca aaagtcagtt 1450

 cttttattcc agaggtcact gagaaaagta ccatctgcta aaattctctt 1500

 tcaagcactt cttccatcat atcctagagg tgagatatgg gaaacagaaa 1550

 gcaaatcagt gttcctcagg agctatatct gttactcaat tgagggtaag 1600

 acaaagtgac aatgaagata tgagtagtat ttccttccaa tttttaaaga 1650

 ttttcagaag ctgagatcaa accccactca ataaaatgca ggagactaga 1700

 agcaacaact tattttggac tcctgagatc aaacacattg aactttcaaa 1750

 tctgggtgtt tctatcaaaa tgtgattttc ataaaatcag taagctagtc 1800

 ctacataaaa aagcatgagc tgaaagtgga ggaccctcta tcttctcatt 1850

 ccttaactga gccaccgatg ttaagaaaaa aatggcttaa gcggtacctt 1900

 caacaactat tctagttaag aaggtgacaa caaattgagg ccgcgaattc 1950

 ggcgaaaact ctttcctttg gttgtgctaa gaggtgatgc ccaaggtgca 2000

 ccacctttca agaactggat catgaacaac tttatcctcc tggaagaaca 2050

 gctcatcaag aaatcccaac aaaagagaag aacttctccc tcgaacttta 2100

 aagtccgctt ctttgtgtta accaaagcca gcctggcata ctttgaagat 2150

 cgtcatggga agaagcgcac gctgaagggg tccattgagc tctcccgaat 2200

 caaatgtgtt gagattgtga aaagtgacat cagcatccca tgccactata 2250

 aatacccgtt tcaggtggtg catgacaact acctcctata tgtgtttgct 2300

 ccagatcgtg agagccggca gcgctgggtg ctggccctta aagaagaaac 2350

 gaggaataat aacagtttgg tgcctaaata tcatcctaat ttctggatgg 2400

 atgggaagtg gaggtgctgt tctcagctgg agaagcttgc aacaggctgt 2450

 gcccaatatg atccaaccaa gaatgcttca aagaagcctc ttcctcctac 2500

 tcctgaagac aacaggcgac cactttggga acctgaagaa actgtggtca 2550

 ttgccttata tgactaccaa accaatgatc ctcaggaact cgcactgcgg 2600

 cgcaacgaag agtactgcct gctggacagt tctgagattc actggtggag 2650

 agtccaggac aggaatgggc atgaaggata tgtaccaagc agttatctgg 2700

 tggaaaaatc tccaaataat ctggaaacct atgagtggta caataagagt 2750

 atcagccgag acaaagctga aaaacttctt ttggacacag gcaaagaagg 2800

 agccttcatg gtaagggatt ccaggactgc aggaacatac accgtgtctg 2850

 ttttcaccaa ggctgttgta agtgagaaca atccctgtat aaagcattat 2900

 cacatcaagg aaacaaatga caatcctaag cgatactatg tggctgaaaa 2950

 gtatgtgttc gattccatcc ctcttctcat caactatcac caacataatg 3000

 gaggaggcct gtggactcga ctccggtatc cagtttgttt tgggaggcag 3050

 aaagccccag ttacagcagg gctgagatac gggaaatggg tgatcgaccc 3100

 ctcagagctc acttttgtgc aagagattgg cagtgggcaa tttgggttgg 3150

 tgcatctggg ctactggctc aacaaggaca aggtggctat caaaaccatt 3200

 cgggaagggg ctatgtcaga agaggacttc atagaggagg ctgaagtaat 3250

 gatgaaactc tctcatccca aactggtgca gctgtatggg gtgtgcctgg 3300

 agcaggcccc catctgcctg gtgtttgagt tcatggagca cggctgcctg 3350

 tcagattatc tacgcaccca gcggggactt tttgctgcag agaccctgct 3400

 gggcatgtgt ctggatgtgt gtgagggcat ggcctacctg gaagaggcat 3450

 gtgtcatcca cagagacttg gctgccagaa attgtttggt gggagaaaac 3500

 caagtcatca aggtgtctga ctttgggatg acaaggttcg ttctggatga 3550

 tcagtacacc agttccacag gcaccaaatt cccggtgaag tgggcatccc 3600

 cagaggtttt ctctttcagt cgctatagca gcaagtccga tgtgtggtca 3650

 tttggtgtgc tgatgtggga agttttcagt gaaggcaaaa tcccgtatga 3700

 aaaccgaagc aactcagagg tggtggaaga catcagtacc ggatttcggt 3750

 tgtacaagcc ccggctggcc tccacacacg tctaccagat tatgaatcac 3800

 tgctggaaag agagaccaga agatcggcca gccttctcca gactgctgcg 3850

 tcaactggct gaaattgcag aatcaggact ttagtagaga ctgagtacca 3900

 ggccacgggc tcagatcctg aatggaggaa ggatatgtcc tcattccata 3950

 gagcattaga agctgccacc agcccaggac cctccagagg cagcctggcc 4000

 tgtactcagt ccctgagtca ccatggaagc agcatcctga ccacagctgg 4050

 cagtcaagcc acagctggag ggtcagccac caagctggga gctgagccag 4100

 aacaggagtg atgtctctgc ccttcctcta gcctcttgtc acatgtggtg 4150

 cacaaacctc aacctgacag ctttcagaca gcattcttgc acttcttagc 4200

 aacagagaga gacatgacgt aagacccaga ttgctatttt tattgttatt 4250

 tttcaacagt gaatctaaag tttatggttc cagggacttt ttatttgacc 4300

 caacaacaca gtatcccagg atatggaggc aaggggaaca agagcatgag 4350

 tgtttttcca agaaactggt gagttaagta agattagagt gagtgtgctc 4400

 tgttgctgtg atgctgtcag ccacagcttc ctgccgtaga gaatgataga 4450

 gcagctgctc acacaggagg ccggatatct gataagcagc tttatgaggt 4500

 tttacagagt atgctgctac ctctctcctt gaagggagca tggcagaccc 4550

 attggatgga ttggggtgaa cagttcaggt cccatgcttg gagcattggg 4600

 tatctgatgt ctgcaccaga acaagagaac ctctgacggt ggagaaccat 4650

 gtggtgtaag aagagatctt aggtctcttc tttataccaa gctcatgttt 4700

 tataccaagc tcatctttta taccaagctg tgcaggtgac tatgcctcct 4750

 cttctgcaca gaatgcttcc accagcatcc tgagaagaaa tgattacttc 4800

 tgtaaaacat ccttttttcc agcctctggg aatcagcccc cccctctctg 4850

 cactatccga tcctcatcaa cagagggcag cattgtgttg gtcagtgttc 4900

 ccttggcgag caattgaaac ttgtttaggc cctagggttg agcaatttta 4950

 aggttgagac tccaagtctc ctaaaattct aggagagaaa taaagagtct 5000

 gtttttgctc aaaccatcag gatggaaaca gtcaggcact gactggggtg 5050

 cttccaagag gcatgagagt gcctactctg gcttgagcac ttctatatgc 5100

 aaggtgaata tgtactgagc taggagactt ccctgcaaaa tctctgttca 5150

 ccctgggttc acatccccat gaggtaatat tattattccc attttacaaa 5200

 taatgtaact gaggctttaa aaagccaaga catctgccca aagtgatgga 5250

 actagaaagt ctagagctgg tattctagcc caaatctgtc tgaccgcaat 5300

 acacagatta tttattccta ttagacactg gcttctactg aaaatgaaac 5350

 ttattgcaga gggaataaat acaaagatgg aaagccagta aagaagtcag 5400

 tatagaacca ctagcgatag tgttgctctg gcacagacca ctgtggttga 5450

 tgcatggccc tccaacttgg aataggattt tccttttcct attctgtatc 5500

 cttaccttgg tcatgttaat gactttggag ttattcagtt cctgaccctt 5550

 taattctcac aaccaaccag tcatgttgct tgaagccatt atagacgagc 5600

 ttcaaagcaa ctttaaaaga ttgttatgta gaagtatgag ttcttccttt 5650

 aattatcatt ccaactttca gctgtagtct tcttgaacac ttatgaggag 5700

 ggaggacatt ccctgatata agagaggatg gtgttgcaat tggctctttc 5750

 taaatcatgt gacgttttga ctggcttgag attcagatgc ataattttta 5800

 attattgtga agtggagagc ctcaagataa aactctgtca ttacgaagat 5850

 gattttactc agcttatcca aaattatctc tgtttacttt ttagaatttt 5900

 gtacattatc ttttgggatc cttaattaga gatgatttct ggaacattca 5950

 gtctagaaag aaaacattgg aattgactga tctctgtggt ttggtttaga 6000

 aaattcccct gtgcatggta ttaccttttt caagctcaga ttcatctaat 6050

 cctcaactgt acatgtgtac attcttcacc tcctggtgcc ctatcccgca 6100

 aaatgggctt cctgcctggg tttttctctt ctcacatttt ttaaatggtc 6150

 ccctgtgttt gtagagaact cccttataca gagttttggt tctagtttta 6200

 tttcgtagat tttgcatttt gtaccttttg agactatgta tttatatttg 6250

 gatcagatgc atatttatta atgtacagtc actgctagtg ttcaaaataa 6300

 aaatgttaca aatacctgtt atcctttgta gagcacacag agttaaaagt 6350

 tgaatatagc aatattaaag ctgcatttta a 6381

<210> 6369
<211> 620
<212> PRT
<213> Homo sapien

<400> 6369
 Met Asn Asn Phe Ile Leu Leu Glu Glu Gln Leu Ile Lys Lys Ser
   1               5                  10                  15

 Gln Gln Lys Arg Arg Thr Ser Pro Ser Asn Phe Lys Val Arg Phe
                  20                  25                  30

 Phe Val Leu Thr Lys Ala Ser Leu Ala Tyr Phe Glu Asp Arg His
                  35                  40                  45

 Gly Lys Lys Arg Thr Leu Lys Gly Ser Ile Glu Leu Ser Arg Ile
                  50                  55                  60

 Lys Cys Val Glu Ile Val Lys Ser Asp Ile Ser Ile Pro Cys His
                  65                  70                  75

 Tyr Lys Tyr Pro Phe Gln Val Val His Asp Asn Tyr Leu Leu Tyr
                  80                  85                  90

 Val Phe Ala Pro Asp Arg Glu Ser Arg Gln Arg Trp Val Leu Ala
                  95                 100                 105

 Leu Lys Glu Glu Thr Arg Asn Asn Asn Ser Leu Val Pro Lys Tyr
                 110                 115                 120

 His Pro Asn Phe Trp Met Asp Gly Lys Trp Arg Cys Cys Ser Gln
                 125                 130                 135

 Leu Glu Lys Leu Ala Thr Gly Cys Ala Gln Tyr Asp Pro Thr Lys
                 140                 145                 150

 Asn Ala Ser Lys Lys Pro Leu Pro Pro Thr Pro Glu Asp Asn Arg
                 155                 160                 165

 Arg Pro Leu Trp Glu Pro Glu Glu Thr Val Val Ile Ala Leu Tyr
                 170                 175                 180

 Asp Tyr Gln Thr Asn Asp Pro Gln Glu Leu Ala Leu Arg Arg Asn
                 185                 190                 195

 Glu Glu Tyr Cys Leu Leu Asp Ser Ser Glu Ile His Trp Trp Arg
                 200                 205                 210

 Val Gln Asp Arg Asn Gly His Glu Gly Tyr Val Pro Ser Ser Tyr
                 215                 220                 225

 Leu Val Glu Lys Ser Pro Asn Asn Leu Glu Thr Tyr Glu Trp Tyr
                 230                 235                 240

 Asn Lys Ser Ile Ser Arg Asp Lys Ala Glu Lys Leu Leu Leu Asp
                 245                 250                 255

 Thr Gly Lys Glu Gly Ala Phe Met Val Arg Asp Ser Arg Thr Ala
                 260                 265                 270

 Gly Thr Tyr Thr Val Ser Val Phe Thr Lys Ala Val Val Ser Glu
                 275                 280                 285

 Asn Asn Pro Cys Ile Lys His Tyr His Ile Lys Glu Thr Asn Asp
                 290                 295                 300

 Asn Pro Lys Arg Tyr Tyr Val Ala Glu Lys Tyr Val Phe Asp Ser
                 305                 310                 315

 Ile Pro Leu Leu Ile Asn Tyr His Gln His Asn Gly Gly Gly Leu
                 320                 325                 330

 Trp Thr Arg Leu Arg Tyr Pro Val Cys Phe Gly Arg Gln Lys Ala
                 335                 340                 345

 Pro Val Thr Ala Gly Leu Arg Tyr Gly Lys Trp Val Ile Asp Pro
                 350                 355                 360

 Ser Glu Leu Thr Phe Val Gln Glu Ile Gly Ser Gly Gln Phe Gly
                 365                 370                 375

 Leu Val His Leu Gly Tyr Trp Leu Asn Lys Asp Lys Val Ala Ile
                 380                 385                 390

 Lys Thr Ile Arg Glu Gly Ala Met Ser Glu Glu Asp Phe Ile Glu
                 395                 400                 405

 Glu Ala Glu Val Met Met Lys Leu Ser His Pro Lys Leu Val Gln
                 410                 415                 420

 Leu Tyr Gly Val Cys Leu Glu Gln Ala Pro Ile Cys Leu Val Phe
                 425                 430                 435

 Glu Phe Met Glu His Gly Cys Leu Ser Asp Tyr Leu Arg Thr Gln
                 440                 445                 450

 Arg Gly Leu Phe Ala Ala Glu Thr Leu Leu Gly Met Cys Leu Asp
                 455                 460                 465

 Val Cys Glu Gly Met Ala Tyr Leu Glu Glu Ala Cys Val Ile His
                 470                 475                 480

 Arg Asp Leu Ala Ala Arg Asn Cys Leu Val Gly Glu Asn Gln Val
                 485                 490                 495

 Ile Lys Val Ser Asp Phe Gly Met Thr Arg Phe Val Leu Asp Asp
                 500                 505                 510

 Gln Tyr Thr Ser Ser Thr Gly Thr Lys Phe Pro Val Lys Trp Ala
                 515                 520                 525

 Ser Pro Glu Val Phe Ser Phe Ser Arg Tyr Ser Ser Lys Ser Asp
                 530                 535                 540

 Val Trp Ser Phe Gly Val Leu Met Trp Glu Val Phe Ser Glu Gly
                 545                 550                 555

 Lys Ile Pro Tyr Glu Asn Arg Ser Asn Ser Glu Val Val Glu Asp
                 560                 565                 570

 Ile Ser Thr Gly Phe Arg Leu Tyr Lys Pro Arg Leu Ala Ser Thr
                 575                 580                 585

 His Val Tyr Gln Ile Met Asn His Cys Trp Lys Glu Arg Pro Glu
                 590                 595                 600

 Asp Arg Pro Ala Phe Ser Arg Leu Leu Arg Gln Leu Ala Glu Ile
                 605                 610                 615

 Ala Glu Ser Gly Leu
                 620

<210> 6370
<211> 2061
<212> DNA
<213> Homo sapien

<400> 6370
 tgttccgcga tcttctcagg ctctcctagc agcatccatc gccgccaccc 50

 tatcttcact ggcttcacct tctccttctc tcttcgttgc tgagcgacaa 100

 gcttcctagc gctatgactg tcgtctccgt cccgcagcgg gagccgctcg 150

 tcctgggtgg ccgccttgcg ccgcttggct tttcctcccg aggttacttt 200

 ggggccctcc cgatggtgac cacggctccg cctcctttac cccggatccc 250

 ggacccccgg gcactgcccc cgaccctctt cctccctcat ttcctagggg 300

 gagatggccc gtgtctgacc ccccagcctc gcgctccagc agctctgccc 350

 aaccgcagcc tcgccgtggc gggaggcact cctcgggcag cgccgaagaa 400

 gcggcgaaag aagaaggtgc gggccagccc cgcagggcag ctgcccagcc 450

 gcttccacca gtaccagcag caccggccga gtctggaggg cggccggagc 500

 cccgcgaccg gcccgagcgg agcgcaggag gtcccgggcc cggccgccgc 550

 cttggccccg agtcctgcag ccgcagccgg cacggaggga gccagccccg 600

 accttgcccc gctgcggccc gcggctcccg gccaaacccc cctcaggaaa 650

 gaggttttaa aatcaaagat gggaaaatcg gagaaaattg cccttcccca 700

 tggccagctt gttcatggta tacacttgta tgagcaacca aagataaaca 750

 gacagaaaag caaatataac ttgccactaa ccaagatcac ctctgcaaaa 800

 agaaatgaaa acaacttttg gcaggattct gtttcatctg acagaattca 850

 gaagcaggaa aaaaagcctt ttaaaaatac cgagaacatt aaaaattcgc 900

 atttgaagaa atcagcattt ctaactgaag tgagccaaaa ggaaaattat 950

 gctggggcaa agtttagtga tccaccttct cctagtgttc ttccaaagcc 1000

 tcctagtcac tggatgggaa gcactgttga aaattccaac caaaacaggg 1050

 agctgatggc agtacactta aaaaccctcc tcaaagttca aacttagatt 1100

 tcagatttca gtatgtgtgt aaaacataat ttttcccata tccctggact 1150

 cttgagaaaa ttggtacaga aatggaaatt tgccttgttg caacatacaa 1200

 ttgcaaaaga tgagtttaaa aaattacata caaacagctt gtattatatt 1250

 ttatattttg taaatactgt ataccatgta ttatgtgtat attgttcata 1300

 cttgagaggt atattatagt tttgttatga aagtatgtat tttgccctgc 1350

 ccacattgca ggtgttttgt atatatacaa tggataaatt ttaagtgtgt 1400

 gctaaggcac atggaagacc gattttattt gcacaaggta ctgagatttt 1450

 tttcaagaaa cagctgtcaa atctcaaggt gaagatctaa atgtgaacag 1500

 tttactaatg cactactgaa gtttaaatct gtggcacaat caatgtaagc 1550

 atggggtttg tttctctaaa ttgatttgta atctgaaatt actgaacaac 1600

 tcctattccc atttttgcta aactcaattt ctggttttgg tatatatcca 1650

 ttccagctta atgcctctaa ttttaatgcc aacaaaattg gttgtaatca 1700

 aattttaaaa taataataat ttggcccccc cttttaaaat agtcttgact 1750

 ctttgtgtgt gactgtttct catgtttgaa tgtgtgacta ggagatgatt 1800

 ttgtgtggtt ggattttttt gacttctact ttactggctg agtgtgagcc 1850

 gccatgcctg gccataatct acattttctt accaggagca gcattgaggt 1900

 ttttgagcat agtacttgac tactctagag gctgagacgg gagcatctct 1950

 tgagcctgag aagtggagat tgcaattgag ctaggatcag gccactgcac 2000

 tccagcctgg gtaacagacg ctgtctcaaa aaaaaggcca agagaaagta 2050

 agggagacag a 2061

<210> 6371
<211> 327
<212> PRT
<213> Homo sapien

<400> 6371
 Met Thr Val Val Ser Val Pro Gln Arg Glu Pro Leu Val Leu Gly
   1               5                  10                  15

 Gly Arg Leu Ala Pro Leu Gly Phe Ser Ser Arg Gly Tyr Phe Gly
                  20                  25                  30

 Ala Leu Pro Met Val Thr Thr Ala Pro Pro Pro Leu Pro Arg Ile
                  35                  40                  45

 Pro Asp Pro Arg Ala Leu Pro Pro Thr Leu Phe Leu Pro His Phe
                  50                  55                  60

 Leu Gly Gly Asp Gly Pro Cys Leu Thr Pro Gln Pro Arg Ala Pro
                  65                  70                  75

 Ala Ala Leu Pro Asn Arg Ser Leu Ala Val Ala Gly Gly Thr Pro
                  80                  85                  90

 Arg Ala Ala Pro Lys Lys Arg Arg Lys Lys Lys Val Arg Ala Ser
                  95                 100                 105

 Pro Ala Gly Gln Leu Pro Ser Arg Phe His Gln Tyr Gln Gln His
                 110                 115                 120

 Arg Pro Ser Leu Glu Gly Gly Arg Ser Pro Ala Thr Gly Pro Ser
                 125                 130                 135

 Gly Ala Gln Glu Val Pro Gly Pro Ala Ala Ala Leu Ala Pro Ser
                 140                 145                 150

 Pro Ala Ala Ala Ala Gly Thr Glu Gly Ala Ser Pro Asp Leu Ala
                 155                 160                 165

 Pro Leu Arg Pro Ala Ala Pro Gly Gln Thr Pro Leu Arg Lys Glu
                 170                 175                 180

 Val Leu Lys Ser Lys Met Gly Lys Ser Glu Lys Ile Ala Leu Pro
                 185                 190                 195

 His Gly Gln Leu Val His Gly Ile His Leu Tyr Glu Gln Pro Lys
                 200                 205                 210

 Ile Asn Arg Gln Lys Ser Lys Tyr Asn Leu Pro Leu Thr Lys Ile
                 215                 220                 225

 Thr Ser Ala Lys Arg Asn Glu Asn Asn Phe Trp Gln Asp Ser Val
                 230                 235                 240

 Ser Ser Asp Arg Ile Gln Lys Gln Glu Lys Lys Pro Phe Lys Asn
                 245                 250                 255

 Thr Glu Asn Ile Lys Asn Ser His Leu Lys Lys Ser Ala Phe Leu
                 260                 265                 270

 Thr Glu Val Ser Gln Lys Glu Asn Tyr Ala Gly Ala Lys Phe Ser
                 275                 280                 285

 Asp Pro Pro Ser Pro Ser Val Leu Pro Lys Pro Pro Ser His Trp
                 290                 295                 300

 Met Gly Ser Thr Val Glu Asn Ser Asn Gln Asn Arg Glu Leu Met
                 305                 310                 315

 Ala Val His Leu Lys Thr Leu Leu Lys Val Gln Thr
                 320                 325

<210> 6372
<211> 1121
<212> DNA
<213> Homo sapien

<400> 6372
 ctagctctgt gggaaggttt tgggctctct ggctcggatt ttgcaatttc 50

 tccctgggga ctgccgtgga gccgcatcca ctgtggatta taattgcaac 100

 atgacgctgg aagagctcgt ggcgtgcgac aacgcggcgc agaagatgca 150

 gacggtgacc gccgcggtgg aggagctttt ggtggccgct cagcgccagg 200

 atcgcctcac agtgggggtg tacgagtcgg ccaagttgat gaatgtggac 250

 ccagacagcg tggtcctctg cctcttggcc attgacgagg aggaggagga 300

 tgacatcgcc ctgcaaatcc acttcacgct catccagtcc ttctgctgtg 350

 acaacgacat caacatcgtg cgggtgtcgg gcaatgcgcg cctggcgcag 400

 ctcctgggag agccggccga gacccagggc accaccgagg cccgagacct 450

 ccactgtctt cccttcctac agaaccctca cacggacgcc tggaagagcc 500

 acggcttggt ggaggtggcc agctactgcg aagaaagccg gggcaacaac 550

 cagtgggtcc cctacatctc tcttcaggaa cgctgaggcc cttcccagca 600

 gcagaatctg ttgagttgct gccaacaaac aaaaaataca ataaatattt 650

 gaaccccctc ccccccagca caaccccccc aaaacaaccc aacccacgag 700

 gaccatcggg ggcaggtcgt tggagactga agagaaagag agagaggaga 750

 agggagtgag gggccgctgc cgccttcccc atcacggagg gtccagactg 800

 tccactcggg ggtggagtga gactgactgc aagccccacc ctccttgaga 850

 ctggagctga gcgtctgcat acgagagact tggttgaaac ttggttggtc 900

 cttgtctgca ccctcgacaa gaccacactt tgggacttgg gagctggggc 950

 tgaagttgct ctgtacccat gaactcccag tttgcgaatt aataagagac 1000

 aatctatttt gttacttgca cttgttattc gaaccactga gagcgagatg 1050

 ggaagcatag atatctatat ttttatttct actatgaggg ccttgtaata 1100

 aatttctaaa gcctcaaaaa a 1121

<210> 6373
<211> 161
<212> PRT
<213> Homo sapien

<400> 6373
 Met Thr Leu Glu Glu Leu Val Ala Cys Asp Asn Ala Ala Gln Lys
   1               5                  10                  15

 Met Gln Thr Val Thr Ala Ala Val Glu Glu Leu Leu Val Ala Ala
                  20                  25                  30

 Gln Arg Gln Asp Arg Leu Thr Val Gly Val Tyr Glu Ser Ala Lys
                  35                  40                  45

 Leu Met Asn Val Asp Pro Asp Ser Val Val Leu Cys Leu Leu Ala
                  50                  55                  60

 Ile Asp Glu Glu Glu Glu Asp Asp Ile Ala Leu Gln Ile His Phe
                  65                  70                  75

 Thr Leu Ile Gln Ser Phe Cys Cys Asp Asn Asp Ile Asn Ile Val
                  80                  85                  90

 Arg Val Ser Gly Asn Ala Arg Leu Ala Gln Leu Leu Gly Glu Pro
                  95                 100                 105

 Ala Glu Thr Gln Gly Thr Thr Glu Ala Arg Asp Leu His Cys Leu
                 110                 115                 120

 Pro Phe Leu Gln Asn Pro His Thr Asp Ala Trp Lys Ser His Gly
                 125                 130                 135

 Leu Val Glu Val Ala Ser Tyr Cys Glu Glu Ser Arg Gly Asn Asn
                 140                 145                 150

 Gln Trp Val Pro Tyr Ile Ser Leu Gln Glu Arg
                 155                 160

<210> 6374
<211> 600
<212> DNA
<213> Homo sapien

<400> 6374
 agtcttggcg gaggtgacca aagccacgta atgtccgtag ttcgctcatc 50

 cgtccatgcc agatggattg tggggaaggt gattgggaca aaaatgcaaa 100

 agactgctaa agtgagagtg accaggcttg ttctggatcc ctatttatta 150

 aagtatttta ataagcggaa aacctacttt gctcacgatg cccttcagca 200

 gtgcacagtt ggggatattg tgcttctcag agctttacct gttccacgag 250

 caaagcatgt gaaacatgaa ctggctgaga tcgttttcaa agttggaaaa 300

 gtcatagatc cagtgacagg aaagccctgt gctggaacta cctacctgga 350

 gagtccgttg agttcggaaa ccacccagct aagcaaaaat ctggaagaac 400

 tcaatatctc ttcagcacag tgaagcggga gtggaagaag gatctaaagg 450

 gaaaaactga catgtttatg ttatggaaaa agaaattttt ctaagtttca 500

 tcacaaactg tgtccagttt ctctgtggtg tttatgaaat agctaaaagc 550

 aaatgaagta aagggcatac tatggttttt cacaaaaaaa aaaaaaaaaa 600

<210> 6375
<211> 130
<212> PRT
<213> Homo sapien

<400> 6375
 Met Ser Val Val Arg Ser Ser Val His Ala Arg Trp Ile Val Gly
   1               5                  10                  15

 Lys Val Ile Gly Thr Lys Met Gln Lys Thr Ala Lys Val Arg Val
                  20                  25                  30

 Thr Arg Leu Val Leu Asp Pro Tyr Leu Leu Lys Tyr Phe Asn Lys
                  35                  40                  45

 Arg Lys Thr Tyr Phe Ala His Asp Ala Leu Gln Gln Cys Thr Val
                  50                  55                  60

 Gly Asp Ile Val Leu Leu Arg Ala Leu Pro Val Pro Arg Ala Lys
                  65                  70                  75

 His Val Lys His Glu Leu Ala Glu Ile Val Phe Lys Val Gly Lys
                  80                  85                  90

 Val Ile Asp Pro Val Thr Gly Lys Pro Cys Ala Gly Thr Thr Tyr
                  95                 100                 105

 Leu Glu Ser Pro Leu Ser Ser Glu Thr Thr Gln Leu Ser Lys Asn
                 110                 115                 120

 Leu Glu Glu Leu Asn Ile Ser Ser Ala Gln
                 125                 130

<210> 6376
<211> 2225
<212> DNA
<213> Homo sapien

<400> 6376
 cgacatggcg cgcgagctgc gggcgctgct gctgtggggc cgccgcctgc 50

 ggcctttgct gcgggcgccg gcgctggcgg ccgtgccggg aggaaaacca 100

 attctgtgtc ctcggaggac cacagcccag ttgggcccca ggcgaaaccc 150

 agcctggagc ttgcaggcag gacgactgtt cagcacgcag accgccgagg 200

 acaaggagga acccctgcac tcgattatca gcagcacaga gagcgtgcag 250

 ggttccactt ccaaacatga gttccaggcc gagacaaaga agcttttgga 300

 cattgttgcc cggtccctgt actcagaaaa agaggtgttt atacgggagc 350

 tgatctccaa tgccagcgat gccttggaaa aactgcgtca caaactggtg 400

 tctgacggcc aagcactgcc agaaatggag attcacttgc agaccaatgc 450

 cgagaaaggc accatcacca tccaggatac tggtatcggg atgacacagg 500

 aagagctggt gtccaacctg gggacgattg ccagatcggg gtcaaaggcc 550

 ttcctggatg ctctgcagaa ccaggctgag gccagcagca agatcatcgg 600

 ccagtttgga gtgggtttct actcagcttt catggtggct gacagagtgg 650

 aggtctattc ccgctcggca gccccgggga gcctgggtta ccagtggctt 700

 tcagatggtt ctggagtgtt tgaaatcgcc gaagcttcgg gagttagaac 750

 cgggacaaaa atcatcatcc acctgaaatc cgactgcaag gagttttcca 800

 gcgaggcccg ggtgcgagat gtggtaacga agtacagcaa cttcgtcagc 850

 ttccccttgt acttgaatgg aaggcggatg aacaccttgc aggccatctg 900

 gatgatggac cccaaggatg tcggtgagtg gcaacatgag gagttctacc 950

 gctacgtcgc gcaggctcac gacaagcccc gctacaccct gcactataag 1000

 acggacgcac cgctcaacat ccgcagcatc ttctacgtgc ccgacatgaa 1050

 accgtccatg tttgatgtga gccgggagct gggctccagc gttgcactgt 1100

 acagccgcaa agtcctcatc cagaccaagg ccacggacat cctgcccaag 1150

 tggctgcgct tcatccgagg tgtggtggac agtgaggaca ttcccctgaa 1200

 cctcagccgg gagctgctgc aggagagcgc actcatcagg aaactccggg 1250

 acgttttaca gcagaggctg atcaaattct tcattgacca gagtaaaaaa 1300

 gatgctgaga agtatgcaaa gttttttgaa gattacggcc tgttcatgcg 1350

 ggagggcatt gtgaccgcca ccgagcagga ggtcaaggag gacatagcaa 1400

 agctgctgcg ctacgagtcc tcggcgctgc cctccgggca gctaaccagc 1450

 ctctcagaat acgccagccg catgcgggcc ggcacccgca acatctacta 1500

 cctgtgcgcc cccaaccgtc acctggcaga gcactcaccc tactatgagg 1550

 ccatgaagaa gaaagacaca gaggttctct tctgctttga gcagtttgat 1600

 gagctcaccc tgctgcacct tcgtgagttt gacaagaaga agctgatctc 1650

 tgtggagacg gacatagtcg tggatcacta caaggaggag aagtttgagg 1700

 acaggtcccc agccgccgag tgcctatcag agaaggagac ggaggagctc 1750

 atggcctgga tgagaaatgt gctggggtcg cgtgtcacca acgtgaaggt 1800

 gaccctccga ctggacaccc accctgccat ggtcaccgtg ctggagatgg 1850

 gggctgcccg ccacttcctg cgcatgcagc agctggccaa gacccaggag 1900

 gagcgcgcac agctcctgca gcccacgctg gagatcaacc ccaggcacgc 1950

 gctcatcaag aagctgaatc agctgcgcgc aagcgagcct ggcctggctc 2000

 agctgctggt ggatcagata tacgagaacg ccatgattgc tgctggactt 2050

 gttgacgacc ctagggccat ggtgggccgc ttgaatgagc tgcttgtcaa 2100

 ggccctggag cgacactgac agccaggggg ccagaaggac tgacaccaca 2150

 gatgacagcc ccacctcctt gagctttatt tacctaaatt taaaggtatt 2200

 tcttaacccg aaaaaaaaaa aaaaa 2225

<210> 6377
<211> 704
<212> PRT
<213> Homo sapien

<400> 6377
 Met Ala Arg Glu Leu Arg Ala Leu Leu Leu Trp Gly Arg Arg Leu
   1               5                  10                  15

 Arg Pro Leu Leu Arg Ala Pro Ala Leu Ala Ala Val Pro Gly Gly
                  20                  25                  30

 Lys Pro Ile Leu Cys Pro Arg Arg Thr Thr Ala Gln Leu Gly Pro
                  35                  40                  45

 Arg Arg Asn Pro Ala Trp Ser Leu Gln Ala Gly Arg Leu Phe Ser
                  50                  55                  60

 Thr Gln Thr Ala Glu Asp Lys Glu Glu Pro Leu His Ser Ile Ile
                  65                  70                  75

 Ser Ser Thr Glu Ser Val Gln Gly Ser Thr Ser Lys His Glu Phe
                  80                  85                  90

 Gln Ala Glu Thr Lys Lys Leu Leu Asp Ile Val Ala Arg Ser Leu
                  95                 100                 105

 Tyr Ser Glu Lys Glu Val Phe Ile Arg Glu Leu Ile Ser Asn Ala
                 110                 115                 120

 Ser Asp Ala Leu Glu Lys Leu Arg His Lys Leu Val Ser Asp Gly
                 125                 130                 135

 Gln Ala Leu Pro Glu Met Glu Ile His Leu Gln Thr Asn Ala Glu
                 140                 145                 150

 Lys Gly Thr Ile Thr Ile Gln Asp Thr Gly Ile Gly Met Thr Gln
                 155                 160                 165

 Glu Glu Leu Val Ser Asn Leu Gly Thr Ile Ala Arg Ser Gly Ser
                 170                 175                 180

 Lys Ala Phe Leu Asp Ala Leu Gln Asn Gln Ala Glu Ala Ser Ser
                 185                 190                 195

 Lys Ile Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala Phe Met
                 200                 205                 210

 Val Ala Asp Arg Val Glu Val Tyr Ser Arg Ser Ala Ala Pro Gly
                 215                 220                 225

 Ser Leu Gly Tyr Gln Trp Leu Ser Asp Gly Ser Gly Val Phe Glu
                 230                 235                 240

 Ile Ala Glu Ala Ser Gly Val Arg Thr Gly Thr Lys Ile Ile Ile
                 245                 250                 255

 His Leu Lys Ser Asp Cys Lys Glu Phe Ser Ser Glu Ala Arg Val
                 260                 265                 270

 Arg Asp Val Val Thr Lys Tyr Ser Asn Phe Val Ser Phe Pro Leu
                 275                 280                 285

 Tyr Leu Asn Gly Arg Arg Met Asn Thr Leu Gln Ala Ile Trp Met
                 290                 295                 300

 Met Asp Pro Lys Asp Val Gly Glu Trp Gln His Glu Glu Phe Tyr
                 305                 310                 315

 Arg Tyr Val Ala Gln Ala His Asp Lys Pro Arg Tyr Thr Leu His
                 320                 325                 330

 Tyr Lys Thr Asp Ala Pro Leu Asn Ile Arg Ser Ile Phe Tyr Val
                 335                 340                 345

 Pro Asp Met Lys Pro Ser Met Phe Asp Val Ser Arg Glu Leu Gly
                 350                 355                 360

 Ser Ser Val Ala Leu Tyr Ser Arg Lys Val Leu Ile Gln Thr Lys
                 365                 370                 375

 Ala Thr Asp Ile Leu Pro Lys Trp Leu Arg Phe Ile Arg Gly Val
                 380                 385                 390

 Val Asp Ser Glu Asp Ile Pro Leu Asn Leu Ser Arg Glu Leu Leu
                 395                 400                 405

 Gln Glu Ser Ala Leu Ile Arg Lys Leu Arg Asp Val Leu Gln Gln
                 410                 415                 420

 Arg Leu Ile Lys Phe Phe Ile Asp Gln Ser Lys Lys Asp Ala Glu
                 425                 430                 435

 Lys Tyr Ala Lys Phe Phe Glu Asp Tyr Gly Leu Phe Met Arg Glu
                 440                 445                 450

 Gly Ile Val Thr Ala Thr Glu Gln Glu Val Lys Glu Asp Ile Ala
                 455                 460                 465

 Lys Leu Leu Arg Tyr Glu Ser Ser Ala Leu Pro Ser Gly Gln Leu
                 470                 475                 480

 Thr Ser Leu Ser Glu Tyr Ala Ser Arg Met Arg Ala Gly Thr Arg
                 485                 490                 495

 Asn Ile Tyr Tyr Leu Cys Ala Pro Asn Arg His Leu Ala Glu His
                 500                 505                 510

 Ser Pro Tyr Tyr Glu Ala Met Lys Lys Lys Asp Thr Glu Val Leu
                 515                 520                 525

 Phe Cys Phe Glu Gln Phe Asp Glu Leu Thr Leu Leu His Leu Arg
                 530                 535                 540

 Glu Phe Asp Lys Lys Lys Leu Ile Ser Val Glu Thr Asp Ile Val
                 545                 550                 555

 Val Asp His Tyr Lys Glu Glu Lys Phe Glu Asp Arg Ser Pro Ala
                 560                 565                 570

 Ala Glu Cys Leu Ser Glu Lys Glu Thr Glu Glu Leu Met Ala Trp
                 575                 580                 585

 Met Arg Asn Val Leu Gly Ser Arg Val Thr Asn Val Lys Val Thr
                 590                 595                 600

 Leu Arg Leu Asp Thr His Pro Ala Met Val Thr Val Leu Glu Met
                 605                 610                 615

 Gly Ala Ala Arg His Phe Leu Arg Met Gln Gln Leu Ala Lys Thr
                 620                 625                 630

 Gln Glu Glu Arg Ala Gln Leu Leu Gln Pro Thr Leu Glu Ile Asn
                 635                 640                 645

 Pro Arg His Ala Leu Ile Lys Lys Leu Asn Gln Leu Arg Ala Ser
                 650                 655                 660

 Glu Pro Gly Leu Ala Gln Leu Leu Val Asp Gln Ile Tyr Glu Asn
                 665                 670                 675

 Ala Met Ile Ala Ala Gly Leu Val Asp Asp Pro Arg Ala Met Val
                 680                 685                 690

 Gly Arg Leu Asn Glu Leu Leu Val Lys Ala Leu Glu Arg His
                 695                 700

<210> 6378
<211> 4221
<212> DNA
<213> Homo sapien

<400> 6378
 gtcggccgtc ccctttaatt tttaaataca cggtcccctc ttttctctgg 50

 ggggggcaag caagaaatca aagaaggagg agacaagccg tcaattttct 100

 ccaaaacaaa ccccaccggg caatttggtc tcggggtagg gggagacggg 150

 gtgattgcaa attattccag gacgagatcc agttctccag cgggaaaggg 200

 gcaaaggaac gccgcgcgtt ggaagggcca gggtacgcag ctccccttgc 250

 agcgcccgca ggacccccgc aagctcgtgc cggcgaaatc ggagaccgcc 300

 gatctgtcct cgttctctcc tgcacgtctg gctgcattcg gaggaagacc 350

 tggggcgcga gcgagcggcg acagcatgag cctgtgctga cctccgcgcg 400

 gcgggccgag cccagggctt tgtcgcggta cctgcgccca gcccgcgccg 450

 caactctgtg cccagctttt gcaatctttt gttgcagcgc tgaccgcacc 500

 aagttaaatg ctcccttgca atttttcttt tttttgtttg tttgtttaat 550

 ttttggagag ctcgcgatct tggaaaagcc tcagacgcca tctacagtta 600

 aaacgtaggt aactgccctc tcccgcaccc cccccttaca cgccccccac 650

 cctttccacc aaaaaaaggg ggtgcagcgc ggattctggc tgccgtgcgt 700

 cgccagccgg tagacccgtg cttgtttcct ttctcttttt gtttggcttc 750

 taacgcgttg ggactgagtc gccgccgtga gctccccgaa gactgcacaa 800

 actaccgcgg gctcctccgc cccgtctgcg attcggaagc cggcctgggg 850

 gtcgcgtcgg gagccctgcg ctgcagctcc gcaccttagc agcccgggta 900

 ctcatccaga tccacgccgg ggacacacac acagagtaac taaaagtgcg 950

 gcgattctgc acatcgccga ctgctttggg gtaacaaaaa gacccgagtt 1000

 gcctgccgac cgaggacccc cgggagccgg gctcggagca gacgaggtat 1050

 ccggcggcgc ccatttgggg gcttctaact ctttctccac gcagcccctc 1100

 ttctgtcccc tcccctctcg ctccctttta aaatcagtgg caccgaggcg 1150

 cctgcagccg cactcgccag cgactcatct ctccagcggg tttttttttg 1200

 tttgtcgtgt gcgatcctca cactcatgaa catacacagg tctaccccca 1250

 tcacaatagc gagatatggg agatcgcgga acaaaaccca ggatttcgaa 1300

 gagttgtcgt ctataaggtc cgcggagccc agccagagtt tcagcccgaa 1350

 cctcggctcc ccgagcccgc ccgagactcc gaacttgtcg cattgcgttt 1400

 cttgtatcgg gaaatactta ttgttggaac ctctggaggg agaccacgtt 1450

 tttcgtgccg tgcatctgca cagcggagag gagctggtgt gcaaggtgtt 1500

 tgatatcagc tgctaccagg aatccctggc accgtgcttt tgcctgtctg 1550

 ctcatagtaa catcaaccaa atcactgaaa ttatcctggg tgagaccaaa 1600

 gcctatgtgt tctttgagcg aagctatggg gacatgcatt ccttcgtccg 1650

 cacctgcaag aagctgagag aggaggaggc agccagactg ttctaccaga 1700

 ttgcctcggc agtggcccac tgccatgacg gggggctggt gctgcgggac 1750

 ctcaagctgc ggaaattcat ctttaaggac gaagagagga ctcgggtcaa 1800

 gctggaaagc ctggaagacg cctacattct gcggggagat gatgattccc 1850

 tctccgacaa gcatggctgc ccggcttacg taagcccaga gatcttgaac 1900

 accagtggca gctactcggg caaagcagcc gacgtgtgga gcctgggggt 1950

 gatgctgtac accatgttgg tggggcggta ccctttccat gacattgaac 2000

 ccagctccct cttcagcaag atccggcgtg gccagttcaa cattccagag 2050

 actctgtcgc ccaaggccaa gtgcctcatc cgaagcattc tgcgtcggga 2100

 gccctcagag cggctgacct cgcaggaaat tctggaccat ccttggtttt 2150

 ctacagattt tagcgtctcg aattcagcat atggtgctaa ggaagtgtct 2200

 gaccagctgg tgccggacgt caacatggaa gagaacttgg accctttctt 2250

 taactgagct catgccccac ggagacttag caggttccag gagtgagcga 2300

 gggcagcgga aaggagttct tccgggggac acgaattgcc tggctgagta 2350

 gcaagaaaga cacactctta agtttcttgg ttcagagcag gaaaaccttc 2400

 aaggagctga ctgaccacgt agcatggggg caagaggcgt gggatgggga 2450

 ttggggtgag atggatggga gcccgctgga gcttgtcttc cctaacatag 2500

 cctgggagac caccccttgc cacttgggcc acttccgcct accccacttt 2550

 tcattttgtt ccaaaatagt tgcagatcct gacagaatca aaactctctg 2600

 cctcaaacac acatcctggc atcgcactgt tagcatttaa cttcttgtta 2650

 ggattcaggg aaggaacagt tggccaagaa ttttttttct tttaaacaag 2700

 ccaaccacct agctggtaat taatgaggtt cacttaaaaa aaaaattcgg 2750

 tgcacacaga ctgacatgaa acctgggtgc tacagtaaaa gaaaacaaaa 2800

 gtccagtttg tgtctcttaa tcgctcactt caactcattt cttctaaata 2850

 aactatttaa tatcctggtc aggaaatgac atgttaatgc tttgctccct 2900

 gaagggggaa aaaatctgtc ctttaacaag ctattctgtt ttgtgtcaat 2950

 tgggtccgtg gcaaggaagc tattaggaag tcaaacggtc caggatgcat 3000

 tacctgctaa tccttaggtt taaaggggga aagaaaaggg aagaagaaag 3050

 gaaaagagaa atccaactcc tttttcatgt tttgcttttg aacaatgagg 3100

 gtttgtgtga caggcattcc tctttgctga gatgatagca atggcctgag 3150

 attttagcaa gctcctggag tctgatgctt ttgcagtact ctgatcgcaa 3200

 ctaaacattt gtctttgttt tattagaaac tagtgaaaca aagcaggttg 3250

 tcccacatgt ataaaataca gggcagctat ttagttttct ttacagagaa 3300

 tgatcctttt aaggcttgta aggccctctg gtttggacaa aaaccctcag 3350

 tagagacaag cgggaaggat aattagctga aagctatgat gatataaata 3400

 aaaacagctc tctatcccaa tacgcacctt tgtattttca agaactcttc 3450

 tatttattaa ggaaaatgtc acattgtgat gtattaagcc agtacttcaa 3500

 ttacgggttg acttgggatg acatattaca tgctgtagtt aacatttata 3550

 attctttttc cttgtttgag tatttctgtc tctgaaataa ccttttactt 3600

 ggcttttcta gatagcttta tttgatttcg agtggcaaaa tgttttttat 3650

 tacggctttt ctattgctgt atgatacaga actcttttgg cataaatatt 3700

 tgtgttccca gtacctcact tgttcggatt tgactgcctg tatatgtttt 3750

 gtgaaatggt cctgtttttg ggtaggtgac acgtggactc tagtatgtaa 3800

 atgttacttg aatctgtgct tcataatagt gtgtggcatg tatgtgcaga 3850

 ctcttggatg ctttatgcct gcgcaccagg agccctgtcc tcacgttccc 3900

 aggagggcgg cttcaccctt cgtaaccagg agacaaggcg gccatggatt 3950

 tgcccttgat tctattttgc taatggaaga tagaaaggag agaaggtttt 4000

 tttttttttt taacattctg aagatggtgc tgtgtcaaga aggacctttt 4050

 ttttcccctc tcccctattt tttaagtacc ttggaggagg agaggttggt 4100

 gacatgcatg gtggggatct atggcctctg gtgctttgtc ctgtatttgg 4150

 tttaatgttt ttgtcctaat ctcttcaatc aataaaattg tgcgtattta 4200

 actaaaaaaa aaaaaaaaaa a 4221

<210> 6379
<211> 343
<212> PRT
<213> Homo sapien

<400> 6379
 Met Asn Ile His Arg Ser Thr Pro Ile Thr Ile Ala Arg Tyr Gly
   1               5                  10                  15

 Arg Ser Arg Asn Lys Thr Gln Asp Phe Glu Glu Leu Ser Ser Ile
                  20                  25                  30

 Arg Ser Ala Glu Pro Ser Gln Ser Phe Ser Pro Asn Leu Gly Ser
                  35                  40                  45

 Pro Ser Pro Pro Glu Thr Pro Asn Leu Ser His Cys Val Ser Cys
                  50                  55                  60

 Ile Gly Lys Tyr Leu Leu Leu Glu Pro Leu Glu Gly Asp His Val
                  65                  70                  75

 Phe Arg Ala Val His Leu His Ser Gly Glu Glu Leu Val Cys Lys
                  80                  85                  90

 Val Phe Asp Ile Ser Cys Tyr Gln Glu Ser Leu Ala Pro Cys Phe
                  95                 100                 105

 Cys Leu Ser Ala His Ser Asn Ile Asn Gln Ile Thr Glu Ile Ile
                 110                 115                 120

 Leu Gly Glu Thr Lys Ala Tyr Val Phe Phe Glu Arg Ser Tyr Gly
                 125                 130                 135

 Asp Met His Ser Phe Val Arg Thr Cys Lys Lys Leu Arg Glu Glu
                 140                 145                 150

 Glu Ala Ala Arg Leu Phe Tyr Gln Ile Ala Ser Ala Val Ala His
                 155                 160                 165

 Cys His Asp Gly Gly Leu Val Leu Arg Asp Leu Lys Leu Arg Lys
                 170                 175                 180

 Phe Ile Phe Lys Asp Glu Glu Arg Thr Arg Val Lys Leu Glu Ser
                 185                 190                 195

 Leu Glu Asp Ala Tyr Ile Leu Arg Gly Asp Asp Asp Ser Leu Ser
                 200                 205                 210

 Asp Lys His Gly Cys Pro Ala Tyr Val Ser Pro Glu Ile Leu Asn
                 215                 220                 225

 Thr Ser Gly Ser Tyr Ser Gly Lys Ala Ala Asp Val Trp Ser Leu
                 230                 235                 240

 Gly Val Met Leu Tyr Thr Met Leu Val Gly Arg Tyr Pro Phe His
                 245                 250                 255

 Asp Ile Glu Pro Ser Ser Leu Phe Ser Lys Ile Arg Arg Gly Gln
                 260                 265                 270

 Phe Asn Ile Pro Glu Thr Leu Ser Pro Lys Ala Lys Cys Leu Ile
                 275                 280                 285

 Arg Ser Ile Leu Arg Arg Glu Pro Ser Glu Arg Leu Thr Ser Gln
                 290                 295                 300

 Glu Ile Leu Asp His Pro Trp Phe Ser Thr Asp Phe Ser Val Ser
                 305                 310                 315

 Asn Ser Ala Tyr Gly Ala Lys Glu Val Ser Asp Gln Leu Val Pro
                 320                 325                 330

 Asp Val Asn Met Glu Glu Asn Leu Asp Pro Phe Phe Asn
                 335                 340

<210> 6380
<211> 1237
<212> DNA
<213> Homo sapien

<400> 6380
 catctgtcac tggccaccgg tttccgggag taagcggcag ctaccttaca 50

 gccctgacac gagccgggtg ctctctcttc tcaccgcggc ccacgtctcc 100

 tcgctggctc cggtggcctc gctgggtcgc gaggaggcgg aggactgtac 150

 tctgaggcca aaagccagag tcggccctga acgcccacga ctctcagggt 200

 ccagaggccg tgagaccggc cgcggctgaa aggtaaagaa accaagtgga 250

 agagtgtttc ctcctctggc cgtaaagcag ctgtccccgc cctactccgg 300

 accgccccaa agactccatg ggatggacct gagtcagccg aatcctagcc 350

 ccttcccttg ggcctgctgt ggtgctcgac atcagtgaca gacggaagca 400

 gcagaccatc aaggctacgg gaggcccggg gcgcttgcga agatgaagtt 450

 tggctgcctc tccttccggc agccttatgc tggctttgtc ttaaatggaa 500

 tcaagactgt ggagacgcgc tggcgtcctc tgctgagcag ccagcggaac 550

 tgtaccatcg ccgtccacat tgctcacagg gactgggaag gcgatgcctg 600

 tcgggagctg ctggtggaga gactcgggat gactcctgct cagattcagg 650

 ccttgctcag gaaaggggaa aagtttggtc gaggagtgat agcgggactc 700

 gttgacattg gggaaacttt gcaatgcccc gaagacttaa ctcccgatga 750

 ggttgtggaa ctagaaaatc aagctgcact gaccaacctg aagcagaagt 800

 acctgactgt gatttcaaac cccaggtggt tactggagcc catacctagg 850

 aaaggaggca aggatgtatt ccaggtagac atcccagagc acctgatccc 900

 tttggggcat gaagtgtgac aagtgtgggc tcctgaaagg aatgttccag 950

 agaaaccagc taaatcatgg caccttcaat ttgccatcgt gacgcagacc 1000

 tgtataaatt aggttaaaga tgaatttcca ctgctttgga gagtcccacc 1050

 cactaagcac tgtgcatgta aacaggttcc tttgctcaga tgaaggaagt 1100

 agggggtggg gctttccttg tgtgatgcct ccttaggcac acaggcaatg 1150

 tctcaagtac tttgacctta gggtagaagg caaagctgcc agtaaatgtc 1200

 tcagcattgc tgctaatttt ggtcctgcta gtttctg 1237

<210> 6381
<211> 2827
<212> DNA
<213> Homo sapien

<400> 6381
 cgcctacaca atgaaattgt ctacgccgtg gaaaaactct ccaaggaaaa 50

 caacagctat tccgtggatg ccgccgaggt cactgaactg catgtcatca 100

 gttatgaagt ggagcgggac ctgactccac tgattctctc caactgccag 150

 taccaggtgg aggagggcag agagaccgtg caggagttcg atctggagaa 200

 gattcagcgg cagatcgtca gccgcttcct ccagggcaag ccccggctga 250

 gcctcaaggg aatacccact ctggtgtaca gacacgactg gaactatgaa 300

 catctcttta tggacatcaa gaacaaaatg gcacaggact ccctccccag 350

 ctcggtcatt agtgccatca gtggacagct gcagtcctac agcgatgcct 400

 gtgaagtgct gtctgtcgta gaagtcactc tggggtttct gagcacagct 450

 ggtggggatc caaacatgca gctgaatgtg tatactcaag acatcctgca 500

 aatgggtgat cagacgattc acgtgttaaa ggccttaaac agatgccagt 550

 taaaacacac cattgccctc tggcagttcc tgtctgctca taagtctgaa 600

 cagctgctgc ggctgcacaa agagccattt ggggaaatca gttcaaggta 650

 caaagcggat ctgagcccgg aaaatgctaa gctcctcagc acattcctaa 700

 atcagactgg cctagacgcc ttcctgctag agctgcacga aatgataatc 750

 ttgaaactaa agaaccccca aacccaaacc gaggagcgct tccgccctca 800

 gtggagcctg agagacactc tcgtaagtta catgcaaact aaagaaagtg 850

 aaattcttcc tgaaatggca tctcagttcc cagaagagat actgcccgcc 900

 agctgtgtct cagtgtggaa aacagctgct gtgctgaaat ggaatcgaga 950

 aatgagatag aattatttcc tcagctatct ttggatgact ttggagagaa 1000

 gactcctctc tcctcgtctg cggcgtggac ttgatcatgg actggtgcct 1050

 ttgcattcag aaggagagct gtcagcgtag caccgaattc aagaccaagg 1100

 cgtgctacct gagctgacag ctttttgaaa gccgagctgt ttctgaacca 1150

 tgtacataca tgttctgaaa ctttctcatc attttatgag tactgttcat 1200

 tgagagatga caatgaagat tagatgaaat tggaaataaa ccaacattgt 1250

 ttacattcca ggagacttgt agctcagcca cacacgcagt aatgacctgt 1300

 gcccgttcgc ctctggcact gcccacccct cttttttttt ttcttctaat 1350

 tctgtactca caaaagagaa tctcattttc ttctttcttc cattccctta 1400

 aattctgagt actgtacata tatttctggg ttcccacgat gatgtgaaaa 1450

 actaccagac tgttttttgt cttctcacaa agacaagaaa aatcagggca 1500

 ttttgtgagt gccttaagat caaactaaca agatctgacc ctctcccctc 1550

 acagtgagcc actgccccac ttcagagggt aagagccaaa agcctcattg 1600

 tgaaaggcac tggacttgga ccagggacac catcagggcc ttggttttct 1650

 cacgcataaa atggagagtg gattaatcgc caaagattct tctgatctga 1700

 cattttgaaa ttgtgagaga aactagatga ctgtaaactt ggtcacaggc 1750

 ctggttctgg cagttctttg cggacttttt tctagcatta tgccaaataa 1800

 acatgcagtc tcagtgtgct ctcgcatgta tgaatatcta gtcctttctg 1850

 tggttctcag ccaagacata aaaactagga ctcagagcac atacaaaacc 1900

 agttatgttt cggaaagagg gaaaagagtc cccgagcccg gatcttgtgc 1950

 tgcttttctc actgacgtgt tgcctttttt ctttacaaaa tctgctttga 2000

 tacttaggac ctctctggac taatttctct tcctagacag ctcagcacag 2050

 ctattgatat gttagaggca gtatccttaa tattcattct aaatgagtta 2100

 acgacttaac ttgaaattgg gcctaaggag tgagaactac aaaaatacaa 2150

 aatgcttgtc caggactcag ccatgcacac cttgagcagc gccggcagga 2200

 ggcacggaag gaactgtgct ccgttctcct cactgtcatg gtgccaccag 2250

 tgtctgatga agggcagagt gacccagact gcaggcagta actgacttca 2300

 cacagtccct ggcatttagt catctgtgat tgttttatca ctctggactg 2350

 tgcagagcca cctgccaccg agatctgcat tccgactgcc tatgaacggg 2400

 tgtgggggcc gggggctggc ttgctgaagt cttcaacttg cactcggagc 2450

 tcctttgata cctcagagct ggctgtcagg tggcagctca cacccagact 2500

 cactggccac acctcagcag ggggggagtc gagtgtcagt ctctttctgt 2550

 gaaggctttt tttttccttt ggcctgggaa tttttcccat ttttatgaag 2600

 gggttttaaa ttgtttcatt ttgtgtgctg tgcttcaaag ccttaactgt 2650

 caaatcttgc attatcttgt ttgtacagaa atatactggc ctagcagagg 2700

 caaaaaaaaa aaaaatgaat tttattttac ttgtcacacc tgtcttaata 2750

 aactggagtt ttgctgctaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2800

 aaaaaaaaaa aaaaaaaaaa aaaaaaa 2827

<210> 6382
<211> 216
<212> PRT
<213> Homo sapien

<400> 6382
 Met Asp Ile Lys Asn Lys Met Ala Gln Asp Ser Leu Pro Ser Ser
   1               5                  10                  15

 Val Ile Ser Ala Ile Ser Gly Gln Leu Gln Ser Tyr Ser Asp Ala
                  20                  25                  30

 Cys Glu Val Leu Ser Val Val Glu Val Thr Leu Gly Phe Leu Ser
                  35                  40                  45

 Thr Ala Gly Gly Asp Pro Asn Met Gln Leu Asn Val Tyr Thr Gln
                  50                  55                  60

 Asp Ile Leu Gln Met Gly Asp Gln Thr Ile His Val Leu Lys Ala
                  65                  70                  75

 Leu Asn Arg Cys Gln Leu Lys His Thr Ile Ala Leu Trp Gln Phe
                  80                  85                  90

 Leu Ser Ala His Lys Ser Glu Gln Leu Leu Arg Leu His Lys Glu
                  95                 100                 105

 Pro Phe Gly Glu Ile Ser Ser Arg Tyr Lys Ala Asp Leu Ser Pro
                 110                 115                 120

 Glu Asn Ala Lys Leu Leu Ser Thr Phe Leu Asn Gln Thr Gly Leu
                 125                 130                 135

 Asp Ala Phe Leu Leu Glu Leu His Glu Met Ile Ile Leu Lys Leu
                 140                 145                 150

 Lys Asn Pro Gln Thr Gln Thr Glu Glu Arg Phe Arg Pro Gln Trp
                 155                 160                 165

 Ser Leu Arg Asp Thr Leu Val Ser Tyr Met Gln Thr Lys Glu Ser
                 170                 175                 180

 Glu Ile Leu Pro Glu Met Ala Ser Gln Phe Pro Glu Glu Ile Leu
                 185                 190                 195

 Pro Ala Ser Cys Val Ser Val Trp Lys Thr Ala Ala Val Leu Lys
                 200                 205                 210

 Trp Asn Arg Glu Met Arg
                 215

<210> 6383
<211> 1519
<212> DNA
<213> Homo sapien

<400> 6383
 ggcacgagga agtggagggg gtgaaagtga gggaggagaa tggacagaat 50

 actgactgga acgttaattc gagcatttca tatgcgaaga gcggaataac 100

 agttccgtat tcttctttca gtttctccat tagattagct tcattttcga 150

 atgctccgtt ttgcatgctt aattttgaaa ctagcccgtg gtttggcaga 200

 atttgactga attcaggggt gagagtttga tccagtccaa gtgtatttga 250

 atttgagcac gcagttcaac cagtgtttac aatggaattt ctgaagactt 300

 gtgtacttag aagaaatgca tgcactgcgg tttgcttctg gagaagcaaa 350

 gttgtccaaa agccttcagt tagaaggatt agtactacct ctcctaggag 400

 cactgtcatg cctgcttggg tgatagataa atatgggaag aatgaagtgc 450

 ttcgattcac tcagaacatg atgatgccta tcatacacta tccaaatgaa 500

 gtcattgtca aagttcacgc tgccagtgta aatcctatag acgttaatat 550

 gagaagtggt tatggagcta cagctttaaa tatgaagcgt gatcctttac 600

 acgtgaaaat caaaggagaa gaatttcctc tgactctggg tcgggatgtc 650

 tctggcgtgg tgatggaatg tgggcttgat gtgaaatact tcaagcctgg 700

 agatgaggtc tgggctgcag ttcctccttg gaaacaaggc actctttcag 750

 agtttgttgt agtcagtggg aatgaggtct ctcacaaacc caaatcactc 800

 actcatactc aagctgcctc tttgccatat gtggctctca cagcctggtc 850

 tgctataaac aaagttggtg gcctgaatga caagaattgc acaggaaaac 900

 gtgttctaat cttaggcgct tcaggcggag ttggtacttt tgctatacag 950

 gtaatgaaag catgggatgc tcatgtgaca gcagtttgct cccaagatgc 1000

 cagtgaactt gtaaggaagc ttggtgcaga cgatgtaatt gattacaaat 1050

 ctggaagtgt ggaagagcag ttgaaatcct taaaaccatt tgattttatc 1100

 cttgataatg ttggcggatc cactgaaaca tgggctccag attttctcaa 1150

 gaaatggtca ggagccacct atgtgacttt ggtgactcct ttcctcctga 1200

 acatggaccg attgggcata gcagatggca tgttgcagac aggagtcact 1250

 gtaggttcaa aggcattaaa gcatttctgg aaaggagtcc attatcgctg 1300

 ggcatttttc atggccagtg gcccatgttt agatgacatt gcagaactgg 1350

 tggatgcggg aaagatccgg ccagttattg aacaaacctt tcctttttct 1400

 aaagttccag aagccttcct gaaggtggaa agaggacacg cacgaggaaa 1450

 gactgtaatt aatgttgttt aaataaaaat gcagtttagt gaaaaaaaaa 1500

 aaaaaaaaaa aaaaaaaaa 1519

<210> 6384
<211> 354
<212> PRT
<213> Homo sapien

<400> 6384
 Met Pro Ala Trp Val Ile Asp Lys Tyr Gly Lys Asn Glu Val Leu
   1               5                  10                  15

 Arg Phe Thr Gln Asn Met Met Met Pro Ile Ile His Tyr Pro Asn
                  20                  25                  30

 Glu Val Ile Val Lys Val His Ala Ala Ser Val Asn Pro Ile Asp
                  35                  40                  45

 Val Asn Met Arg Ser Gly Tyr Gly Ala Thr Ala Leu Asn Met Lys
                  50                  55                  60

 Arg Asp Pro Leu His Val Lys Ile Lys Gly Glu Glu Phe Pro Leu
                  65                  70                  75

 Thr Leu Gly Arg Asp Val Ser Gly Val Val Met Glu Cys Gly Leu
                  80                  85                  90

 Asp Val Lys Tyr Phe Lys Pro Gly Asp Glu Val Trp Ala Ala Val
                  95                 100                 105

 Pro Pro Trp Lys Gln Gly Thr Leu Ser Glu Phe Val Val Val Ser
                 110                 115                 120

 Gly Asn Glu Val Ser His Lys Pro Lys Ser Leu Thr His Thr Gln
                 125                 130                 135

 Ala Ala Ser Leu Pro Tyr Val Ala Leu Thr Ala Trp Ser Ala Ile
                 140                 145                 150

 Asn Lys Val Gly Gly Leu Asn Asp Lys Asn Cys Thr Gly Lys Arg
                 155                 160                 165

 Val Leu Ile Leu Gly Ala Ser Gly Gly Val Gly Thr Phe Ala Ile
                 170                 175                 180

 Gln Val Met Lys Ala Trp Asp Ala His Val Thr Ala Val Cys Ser
                 185                 190                 195

 Gln Asp Ala Ser Glu Leu Val Arg Lys Leu Gly Ala Asp Asp Val
                 200                 205                 210

 Ile Asp Tyr Lys Ser Gly Ser Val Glu Glu Gln Leu Lys Ser Leu
                 215                 220                 225

 Lys Pro Phe Asp Phe Ile Leu Asp Asn Val Gly Gly Ser Thr Glu
                 230                 235                 240

 Thr Trp Ala Pro Asp Phe Leu Lys Lys Trp Ser Gly Ala Thr Tyr
                 245                 250                 255

 Val Thr Leu Val Thr Pro Phe Leu Leu Asn Met Asp Arg Leu Gly
                 260                 265                 270

 Ile Ala Asp Gly Met Leu Gln Thr Gly Val Thr Val Gly Ser Lys
                 275                 280                 285

 Ala Leu Lys His Phe Trp Lys Gly Val His Tyr Arg Trp Ala Phe
                 290                 295                 300

 Phe Met Ala Ser Gly Pro Cys Leu Asp Asp Ile Ala Glu Leu Val
                 305                 310                 315

 Asp Ala Gly Lys Ile Arg Pro Val Ile Glu Gln Thr Phe Pro Phe
                 320                 325                 330

 Ser Lys Val Pro Glu Ala Phe Leu Lys Val Glu Arg Gly His Ala
                 335                 340                 345

 Arg Gly Lys Thr Val Ile Asn Val Val
                 350

<210> 6385
<211> 1444
<212> DNA
<213> Homo sapien

<400> 6385
 ggggggggcg gggcgcccag cgggatgcgg tgaagggcga gcggcgcggc 50

 ggctgcgatg agtgcctctg cggccaccgg ggtcttcgtg ctgtccctct 100

 cggccatccc ggtcacctat gtcttcaacc acctggcggc ccagcatgat 150

 tcctggacta ttgtaggggt tgctgccctc atcctgttcc tggtagcact 200

 gctggctcgt gtcctcgtca aaagaaaacc accccgggac ccactgttct 250

 atgtgtatgc agtttttgga tttaccagcg tggtgaacct catcatagga 300

 ctggagcaag atggaatcat tgacgggttc atgacacact acttgagaga 350

 gggtgaaccg tatctgaaca ccgcatatgg gcacatgatc tgctactggg 400

 atggctctgc tcattatctg atgtacctgg tgatggtggc agccatagca 450

 tgggaggaaa cttatagaac cattggccta tattgggttg gatctattat 500

 tatgagtgtt gttgtttttg tgccaggaaa cattgtaggg aagtatggaa 550

 cacgaatttg ccctgctttt ttcttaagca taccatatac ttgtcttcct 600

 gtctgggctg gtttcagaat ctataatcag ccatcagaaa attataatta 650

 cccctcaaag gttattcaag aagcccaagc gaaagacctg ctgagaagac 700

 catttgattt aatgttggtt gtgtgtctcc tcctggcaac tggattttgc 750

 ctgttcagag gtttgattgc tttggattgc ccatctgagc tctgccgatt 800

 atatacgcaa tttcaagagc cctatctaaa ggatcctgct gcttatccta 850

 aaattcagat gctggcatat atgttctatt ctgttcctta ctttgtgact 900

 gcactgtatg gcttagtggt tcctggatgt tcctggatgc ctgacatcac 950

 attgatacat gctggaggtc tggctcaggc tcagttttct cacattggtg 1000

 catctcttca tgctagaact gcttatgtct acagagtccc tgaagaagca 1050

 aaaatccttt ttttagcatt aaacatagta tatggagttc ttcctcagct 1100

 cttggcctat cgttgtatct acaaaccaga gttcttcata aaaacaaagg 1150

 cagaagaaaa agtggaataa aaatattact tcatgttcct cctttctaaa 1200

 ttactaactt ttgttatact ggtactgata ttttgtccca tttcactctc 1250

 ttctcatacg tgagtactta agaatatgta cattcttgct ctgcactgta 1300

 tgtgtgagct atatggtatt gtgtaaattt tttttgaagg aaaatggaaa 1350

 ttcttgagaa acagtttgtt taaagaaata tattcaaaat catttgtgaa 1400

 taaacttgat catccatctc aaaaaaaaaa aaaaaaaaaa aaaa 1444

<210> 6386
<211> 370
<212> PRT
<213> Homo sapien

<400> 6386
 Met Ser Ala Ser Ala Ala Thr Gly Val Phe Val Leu Ser Leu Ser
   1               5                  10                  15

 Ala Ile Pro Val Thr Tyr Val Phe Asn His Leu Ala Ala Gln His
                  20                  25                  30

 Asp Ser Trp Thr Ile Val Gly Val Ala Ala Leu Ile Leu Phe Leu
                  35                  40                  45

 Val Ala Leu Leu Ala Arg Val Leu Val Lys Arg Lys Pro Pro Arg
                  50                  55                  60

 Asp Pro Leu Phe Tyr Val Tyr Ala Val Phe Gly Phe Thr Ser Val
                  65                  70                  75

 Val Asn Leu Ile Ile Gly Leu Glu Gln Asp Gly Ile Ile Asp Gly
                  80                  85                  90

 Phe Met Thr His Tyr Leu Arg Glu Gly Glu Pro Tyr Leu Asn Thr
                  95                 100                 105

 Ala Tyr Gly His Met Ile Cys Tyr Trp Asp Gly Ser Ala His Tyr
                 110                 115                 120

 Leu Met Tyr Leu Val Met Val Ala Ala Ile Ala Trp Glu Glu Thr
                 125                 130                 135

 Tyr Arg Thr Ile Gly Leu Tyr Trp Val Gly Ser Ile Ile Met Ser
                 140                 145                 150

 Val Val Val Phe Val Pro Gly Asn Ile Val Gly Lys Tyr Gly Thr
                 155                 160                 165

 Arg Ile Cys Pro Ala Phe Phe Leu Ser Ile Pro Tyr Thr Cys Leu
                 170                 175                 180

 Pro Val Trp Ala Gly Phe Arg Ile Tyr Asn Gln Pro Ser Glu Asn
                 185                 190                 195

 Tyr Asn Tyr Pro Ser Lys Val Ile Gln Glu Ala Gln Ala Lys Asp
                 200                 205                 210

 Leu Leu Arg Arg Pro Phe Asp Leu Met Leu Val Val Cys Leu Leu
                 215                 220                 225

 Leu Ala Thr Gly Phe Cys Leu Phe Arg Gly Leu Ile Ala Leu Asp
                 230                 235                 240

 Cys Pro Ser Glu Leu Cys Arg Leu Tyr Thr Gln Phe Gln Glu Pro
                 245                 250                 255

 Tyr Leu Lys Asp Pro Ala Ala Tyr Pro Lys Ile Gln Met Leu Ala
                 260                 265                 270

 Tyr Met Phe Tyr Ser Val Pro Tyr Phe Val Thr Ala Leu Tyr Gly
                 275                 280                 285

 Leu Val Val Pro Gly Cys Ser Trp Met Pro Asp Ile Thr Leu Ile
                 290                 295                 300

 His Ala Gly Gly Leu Ala Gln Ala Gln Phe Ser His Ile Gly Ala
                 305                 310                 315

 Ser Leu His Ala Arg Thr Ala Tyr Val Tyr Arg Val Pro Glu Glu
                 320                 325                 330

 Ala Lys Ile Leu Phe Leu Ala Leu Asn Ile Val Tyr Gly Val Leu
                 335                 340                 345

 Pro Gln Leu Leu Ala Tyr Arg Cys Ile Tyr Lys Pro Glu Phe Phe
                 350                 355                 360

 Ile Lys Thr Lys Ala Glu Glu Lys Val Glu
                 365                 370

<210> 6387
<211> 2125
<212> DNA
<213> Homo sapien

<400> 6387
 aatgaaggcc catgtagcaa aatactgatt caatgtaaag caaactttga 50

 aaataagcta atagtcctta aagaaaaact tatttcagat agcaaaagac 100

 aagccaatga actcattagt tttaaaaacc aaagtcaaga aaggctgaat 150

 aagaaaaaga cagattatga aaaagaatta ttggaaaaaa gccggaagtt 200

 ggctttaact gtaaagggca aagaattgag tgaggaagag ttacatgaga 250

 aattcaatca actttggaaa aagtgggtgt gtgatgtatc cacaactctc 300

 ccgcaagtta cagagcctga cattgatttg gattctgaaa acatcctttg 350

 ggagtatttc aaaaacaaga cgaatgtcgt gggtctactg acaaattctg 400

 cagagaagtt tcaaatcaat tatgataaac atatcaaggt gaataagaaa 450

 tataaccata tcccaatgac attaacagtc tttgagaaag agttcattaa 500

 tatgactact gactacattg tttcaagatt taataaaatt attaacaaca 550

 tgtggaaaca acagtgtggt tacaatccaa attatttcca tgagattcta 600

 aagacaatag aagaagaagt gaaatctgcc tctactcaga agagatacac 650

 atttacaaat acatttatca ttgacttatg tgtgtgttta tttcaaagag 700

 caagagagaa ttttaaggaa atgcacaggg cattcaagag agcaaatgat 750

 cctgtaaact acctagaaag taagaaagat gatttcttca cgagttttaa 800

 gatctcctgt caaggagcaa cctccatcaa aacatttgtt gatattctgt 850

 ggtataagct cactcctgca gtctccacta ctatatggga ggacatgacc 900

 tttaaaattg cgggggacat gcgagctacc tgccctgcgt tcaatggaaa 950

 caggactaac ctggagaaac acattctctt ctctctggca gaagaagaaa 1000

 actttgataa ttactgggaa taccttcata attcaaaatc gttttttagg 1050

 agttacatca aaaatcatat taaaagatat tgttcagaca atggaggtga 1100

 aaaaatgaag actttttttg aaaaaagctt aattgatatc aagaatacca 1150

 tcctctctgc catccatgaa tccacatcag tagctaaaga taaaagcagc 1200

 actgcttctg agtggttgga tttattctgt gattgcctgg ggtgcaactt 1250

 gatctttcca cgaagggact tgataagcat tgaacaccag gagataaaac 1300

 atactgaatt tcttaaagaa gccatgagtg cagctttgga tctcacaatg 1350

 aagaaaatag aacagaatta ttcaagtaag cctatagaag caatggtttc 1400

 taaaattgag aaaatgctct ctgaacatct ctgtggctgc tggaaacagt 1450

 gtcccagctg tggagcaatt tgtacaaaca caattcctac acatgaagga 1500

 gaccatagtg ttcccttcca ccgtcctcag gctgtcaatg gggaggaatg 1550

 gtatgaaaca gatgattttg tcattgattg ctgtactagt ttggttgcaa 1600

 gtgattgttt gttggttttg agggatggca ggaatttccc atttaagaac 1650

 tatcgacaag caggagggga ttatgccatg tggagcatca ccccagatac 1700

 ctccatccag ctatactgga aatggtttgt ctctcacttc agatcaaatc 1750

 tagaagaaaa atatcagaaa aaatttgcag gtaaaggtaa aatccccaat 1800

 gcatgggcca aaatcacaaa gcaagatgtg cttgaagact tgaaaaaaca 1850

 gtaatactca gtgaccacaa aagagcccca gtgtctgaag aaaagaggca 1900

 gtgtacctga acaatccaaa aacaactact cattacaatt agaaccttca 1950

 tcatttccat gtttaaaatg aaatgtgtaa aaatcaatca attaacacat 2000

 taagagatga aaatttccag taaaaggact tcatttctct ctgcctcaat 2050

 tcctctagtt taaaaacaac ttactaaaat ctgttaatat atgatgaaat 2100

 caaataacat tcattttaga aacct 2125

<210> 6388
<211> 462
<212> PRT
<213> Homo sapien

<400> 6388
 Met Thr Leu Thr Val Phe Glu Lys Glu Phe Ile Asn Met Thr Thr
   1               5                  10                  15

 Asp Tyr Ile Val Ser Arg Phe Asn Lys Ile Ile Asn Asn Met Trp
                  20                  25                  30

 Lys Gln Gln Cys Gly Tyr Asn Pro Asn Tyr Phe His Glu Ile Leu
                  35                  40                  45

 Lys Thr Ile Glu Glu Glu Val Lys Ser Ala Ser Thr Gln Lys Arg
                  50                  55                  60

 Tyr Thr Phe Thr Asn Thr Phe Ile Ile Asp Leu Cys Val Cys Leu
                  65                  70                  75

 Phe Gln Arg Ala Arg Glu Asn Phe Lys Glu Met His Arg Ala Phe
                  80                  85                  90

 Lys Arg Ala Asn Asp Pro Val Asn Tyr Leu Glu Ser Lys Lys Asp
                  95                 100                 105

 Asp Phe Phe Thr Ser Phe Lys Ile Ser Cys Gln Gly Ala Thr Ser
                 110                 115                 120

 Ile Lys Thr Phe Val Asp Ile Leu Trp Tyr Lys Leu Thr Pro Ala
                 125                 130                 135

 Val Ser Thr Thr Ile Trp Glu Asp Met Thr Phe Lys Ile Ala Gly
                 140                 145                 150

 Asp Met Arg Ala Thr Cys Pro Ala Phe Asn Gly Asn Arg Thr Asn
                 155                 160                 165

 Leu Glu Lys His Ile Leu Phe Ser Leu Ala Glu Glu Glu Asn Phe
                 170                 175                 180

 Asp Asn Tyr Trp Glu Tyr Leu His Asn Ser Lys Ser Phe Phe Arg
                 185                 190                 195

 Ser Tyr Ile Lys Asn His Ile Lys Arg Tyr Cys Ser Asp Asn Gly
                 200                 205                 210

 Gly Glu Lys Met Lys Thr Phe Phe Glu Lys Ser Leu Ile Asp Ile
                 215                 220                 225

 Lys Asn Thr Ile Leu Ser Ala Ile His Glu Ser Thr Ser Val Ala
                 230                 235                 240

 Lys Asp Lys Ser Ser Thr Ala Ser Glu Trp Leu Asp Leu Phe Cys
                 245                 250                 255

 Asp Cys Leu Gly Cys Asn Leu Ile Phe Pro Arg Arg Asp Leu Ile
                 260                 265                 270

 Ser Ile Glu His Gln Glu Ile Lys His Thr Glu Phe Leu Lys Glu
                 275                 280                 285

 Ala Met Ser Ala Ala Leu Asp Leu Thr Met Lys Lys Ile Glu Gln
                 290                 295                 300

 Asn Tyr Ser Ser Lys Pro Ile Glu Ala Met Val Ser Lys Ile Glu
                 305                 310                 315

 Lys Met Leu Ser Glu His Leu Cys Gly Cys Trp Lys Gln Cys Pro
                 320                 325                 330

 Ser Cys Gly Ala Ile Cys Thr Asn Thr Ile Pro Thr His Glu Gly
                 335                 340                 345

 Asp His Ser Val Pro Phe His Arg Pro Gln Ala Val Asn Gly Glu
                 350                 355                 360

 Glu Trp Tyr Glu Thr Asp Asp Phe Val Ile Asp Cys Cys Thr Ser
                 365                 370                 375

 Leu Val Ala Ser Asp Cys Leu Leu Val Leu Arg Asp Gly Arg Asn
                 380                 385                 390

 Phe Pro Phe Lys Asn Tyr Arg Gln Ala Gly Gly Asp Tyr Ala Met
                 395                 400                 405

 Trp Ser Ile Thr Pro Asp Thr Ser Ile Gln Leu Tyr Trp Lys Trp
                 410                 415                 420

 Phe Val Ser His Phe Arg Ser Asn Leu Glu Glu Lys Tyr Gln Lys
                 425                 430                 435

 Lys Phe Ala Gly Lys Gly Lys Ile Pro Asn Ala Trp Ala Lys Ile
                 440                 445                 450

 Thr Lys Gln Asp Val Leu Glu Asp Leu Lys Lys Gln
                 455                 460

<210> 6389
<211> 1218
<212> DNA
<213> Homo sapien

<400> 6389
 acacaacttc agctgaggaa cttggcacgg ccagcttggg acccaggacc 50

 ctaacgcaga ggcgctgtgt ttggaagtcc cgctatcacg gccccccaga 100

 tggggcctgg acgatgcctc ctgacggcct tgttgcttct ggccctggcg 150

 ccaccgccgg aagcctccca gtactgcggc cgccttgaat actggaaccc 200

 agacaacaag tgctgcagca gctgcctgca acgcttcggg ccgcccccct 250

 gcccggacta tgagttccgg gaaaactgcg gactcaatga ccacggcgat 300

 ttcgtaacgc ccccgttccg aaagtgttct tctgggcagt gcaaccccga 350

 cggcgcggag ctatgtagcc cctgcggcgg cggagccgtg acccctactc 400

 ccgccgcggg cgggggcaga accccgtggc gctgcagaga gaggccggtc 450

 cctgccaagg ggcactgccc cctcacacct ggaaacccag gcgcccctag 500

 ctcccaggag cgcagctcac cagcaagttc cattgcctgg aggacccctg 550

 agcctgtccc tcagcaggcc tggccgaatt tccttccgct cgtggtgctg 600

 gtcctgctcc tgaccttggc ggtgatagcg atcctcctgt ttattctgct 650

 ctggcatctc tgctggccca aggagaaagc cgacccctat ccctatcctg 700

 gcttggtctg cggagtcccc aacacccaca ccccttcctc ctcgcatctg 750

 tcctccccag gcgccctgga gacaggggac acatggaagg aggcctcact 800

 acttccactc ctgagcaggg aactgtccag tctggcgtca caacccctgt 850

 ctcgcctcct ggatgagctg gaggtgctgg aagagctgat tgtactgctg 900

 gaccctgagc ctgggccagg tgggggtatg gcccatggca ctactcgaca 950

 cctggccgca agatatgggc tgcctgctgc ctggtccacc tttgcctatt 1000

 cgctgaggcc gagtcgctcg ccgctgcggg ctctgattga gatggtggtg 1050

 gcaagggagc cctctgcctc cctgggccag cttggcacac acctcgccca 1100

 gctagggcgg gcagatgcat tgcgggtgct gtccaagctt ggctcatctg 1150

 gggtttgctg ggcttaacac ccaataaaga actttgctga ctactaaaaa 1200

 aaaaaaaaaa aaaaaaaa 1218

<210> 6390
<211> 355
<212> PRT
<213> Homo sapien

<400> 6390
 Met Gly Pro Gly Arg Cys Leu Leu Thr Ala Leu Leu Leu Leu Ala
   1               5                  10                  15

 Leu Ala Pro Pro Pro Glu Ala Ser Gln Tyr Cys Gly Arg Leu Glu
                  20                  25                  30

 Tyr Trp Asn Pro Asp Asn Lys Cys Cys Ser Ser Cys Leu Gln Arg
                  35                  40                  45

 Phe Gly Pro Pro Pro Cys Pro Asp Tyr Glu Phe Arg Glu Asn Cys
                  50                  55                  60

 Gly Leu Asn Asp His Gly Asp Phe Val Thr Pro Pro Phe Arg Lys
                  65                  70                  75

 Cys Ser Ser Gly Gln Cys Asn Pro Asp Gly Ala Glu Leu Cys Ser
                  80                  85                  90

 Pro Cys Gly Gly Gly Ala Val Thr Pro Thr Pro Ala Ala Gly Gly
                  95                 100                 105

 Gly Arg Thr Pro Trp Arg Cys Arg Glu Arg Pro Val Pro Ala Lys
                 110                 115                 120

 Gly His Cys Pro Leu Thr Pro Gly Asn Pro Gly Ala Pro Ser Ser
                 125                 130                 135

 Gln Glu Arg Ser Ser Pro Ala Ser Ser Ile Ala Trp Arg Thr Pro
                 140                 145                 150

 Glu Pro Val Pro Gln Gln Ala Trp Pro Asn Phe Leu Pro Leu Val
                 155                 160                 165

 Val Leu Val Leu Leu Leu Thr Leu Ala Val Ile Ala Ile Leu Leu
                 170                 175                 180

 Phe Ile Leu Leu Trp His Leu Cys Trp Pro Lys Glu Lys Ala Asp
                 185                 190                 195

 Pro Tyr Pro Tyr Pro Gly Leu Val Cys Gly Val Pro Asn Thr His
                 200                 205                 210

 Thr Pro Ser Ser Ser His Leu Ser Ser Pro Gly Ala Leu Glu Thr
                 215                 220                 225

 Gly Asp Thr Trp Lys Glu Ala Ser Leu Leu Pro Leu Leu Ser Arg
                 230                 235                 240

 Glu Leu Ser Ser Leu Ala Ser Gln Pro Leu Ser Arg Leu Leu Asp
                 245                 250                 255

 Glu Leu Glu Val Leu Glu Glu Leu Ile Val Leu Leu Asp Pro Glu
                 260                 265                 270

 Pro Gly Pro Gly Gly Gly Met Ala His Gly Thr Thr Arg His Leu
                 275                 280                 285

 Ala Ala Arg Tyr Gly Leu Pro Ala Ala Trp Ser Thr Phe Ala Tyr
                 290                 295                 300

 Ser Leu Arg Pro Ser Arg Ser Pro Leu Arg Ala Leu Ile Glu Met
                 305                 310                 315

 Val Val Ala Arg Glu Pro Ser Ala Ser Leu Gly Gln Leu Gly Thr
                 320                 325                 330

 His Leu Ala Gln Leu Gly Arg Ala Asp Ala Leu Arg Val Leu Ser
                 335                 340                 345

 Lys Leu Gly Ser Ser Gly Val Cys Trp Ala
                 350                 355

<210> 6391
<211> 1005
<212> DNA
<213> Homo sapien

<400> 6391
 gtccaacatg gcggcgccca gcggagggtg gaacggcgtc ggcgcgagct 50

 tgtgggccgc gctgctccta ggggccgtgg cgctgaggcc ggcggaggcg 100

 gtgtccgagc ccacgacggt ggcgtttgac gtgcggcccg gcggcgtcgt 150

 gcattccttc tcccataacg tgggcccggg ggacaaatat acgtgtatgt 200

 tcacttacgc ctctcaagga gggaccaatg agcaatggca gatgagtctg 250

 gggaccagcg aagaccacca gcacttcacc tgcaccatct ggaggcccca 300

 ggggaagtcc tatctgtact tcacacagtt caaggcagag gtgcggggcg 350

 ctgagattga gtacgccatg gcctactcta aagccgcatt tgaaagggaa 400

 agtgatgtcc ctctgaaaac tgaggaattt gaagtgacca aaacagcagt 450

 ggctcacagg cccggggcat tcaaagctga gctgtccaag ctggtgattg 500

 tggccaaggc atcgcgcact gagctgtgac cagcagccct gttgcgggtg 550

 gcaccttctc atctccggtg aagctgaagg ggcctgtgtc cctgaaaggg 600

 ccagcacatc actggttttc taggagggac tcttaagttt tctacctggg 650

 ctgacgttgc cttgtccgga ggggcttgca gggtggctga agccctgggg 700

 cagagaacag agggtccagg gccctcctgg ctcccaacag cttctcagtt 750

 cccacttcct gctgagctct tctggactca ggatcgcaga tccggggcac 800

 aaagagggtg gggaacatgg gggctatgct ggggaaagca gccatgctcc 850

 ccccgacctc cagccgagca tccttcatga gcctgcagaa ctgctttcct 900

 atgtttaccc aggggacctc ctttcagatg aactgggaag agatgaaatg 950

 ttttttcata tttaaataaa taagaacatt aaaaagcaaa aaaaaaaaaa 1000

 aaaaa 1005

<210> 6392
<211> 173
<212> PRT
<213> Homo sapien

<400> 6392
 Met Ala Ala Pro Ser Gly Gly Trp Asn Gly Val Gly Ala Ser Leu
   1               5                  10                  15

 Trp Ala Ala Leu Leu Leu Gly Ala Val Ala Leu Arg Pro Ala Glu
                  20                  25                  30

 Ala Val Ser Glu Pro Thr Thr Val Ala Phe Asp Val Arg Pro Gly
                  35                  40                  45

 Gly Val Val His Ser Phe Ser His Asn Val Gly Pro Gly Asp Lys
                  50                  55                  60

 Tyr Thr Cys Met Phe Thr Tyr Ala Ser Gln Gly Gly Thr Asn Glu
                  65                  70                  75

 Gln Trp Gln Met Ser Leu Gly Thr Ser Glu Asp His Gln His Phe
                  80                  85                  90

 Thr Cys Thr Ile Trp Arg Pro Gln Gly Lys Ser Tyr Leu Tyr Phe
                  95                 100                 105

 Thr Gln Phe Lys Ala Glu Val Arg Gly Ala Glu Ile Glu Tyr Ala
                 110                 115                 120

 Met Ala Tyr Ser Lys Ala Ala Phe Glu Arg Glu Ser Asp Val Pro
                 125                 130                 135

 Leu Lys Thr Glu Glu Phe Glu Val Thr Lys Thr Ala Val Ala His
                 140                 145                 150

 Arg Pro Gly Ala Phe Lys Ala Glu Leu Ser Lys Leu Val Ile Val
                 155                 160                 165

 Ala Lys Ala Ser Arg Thr Glu Leu
                 170

<210> 6393
<211> 1842
<212> DNA
<213> Homo sapien

<400> 6393
 gcgcgccacg gcaggaaagg gcggtcctgc gctgtggccc acgctcgctc 50

 ccgctgtcgg actctgggcc tggaccgcgc gtggccggcg ccaaaagcga 100

 gaggcatgag cgcgcgcccg ggccagtgaa ctgctcgggg atggactgcg 150

 gctcggtcgg cggccagagg acccagcgcc tgcccggccg ccagcggctt 200

 ctcttcttgc ccgtgggcct cagcggaaga ccgggcggca gcgaaacctc 250

 agcacgccgc tgcccctctg cgctctccga cggtctgggg gcgctgcgcc 300

 ctcgcgcccc ggcggcccgc ggcggcgtgt cacgtgcctc accgctgctc 350

 ctcctcctgc tagtgccctc cccgcgcttg gccgccgcag ccccgcgccg 400

 gcagctcggg gactgggagc gctcgcgcct cgggtatgcc gcacccccgg 450

 ccgggcgcag cggcgcgtgg aggtgctcac cgggcgtcgc cgctgccgcc 500

 ggcgcccttc cccagtacca cggcccggcg cctgcactcg tttcctgcag 550

 gagagagcta agcttgtctg ctggatccct gcagctggag cgcaaaagga 600

 gagatttcac ctcttctggg agcaggaaac tctacttcga cactcatgcc 650

 ttagtgtgct tactggaaga caatgaatct cactctttca tccaggctgg 700

 agtgcagtgg cacagtcttg gcctactgca acccccacct cccggtttca 750

 agcgatcctc ccacctcatc ctcctgagta gctgggatta caggcatgca 800

 ccaccacacc tggataattt ttctgtattt ttactagaga cggggtttca 850

 ccatgttggc caggctggtc tcaaactgct gacctcaagt gatccaccca 900

 ccttggcctc ctaaagtgct gggattacag gcgtgaacca ctgtgtccag 950

 ttgccaaacc taattatgtt taaacatgaa ctcttttttt aattaaaatt 1000

 ttttaaaatt ttatttacat taaaatggag atgggatcac tatgttgccc 1050

 atgctggttc tgaactcctg ggctcaaaga tcctcccgcc ttggtctccc 1100

 agagtgttag gattacaggc gtgagccacc acacccagcc agtgaactct 1150

 tcttaataaa actttaaaat ttggcaaaag tttagtttga gtttttaaaa 1200

 actaggaaga cagacgagaa aaaagaaaac agagtcagag ctaaacaatg 1250

 ttaacatttt gggtttgcta ctcaacaagc agaaatcatt gtgtctgcat 1300

 tggtcaagat cctggaggcc aacatggaca tcgtctacaa agatatggtc 1350

 accaagatgc agcaggaaat cacttttcag caagtaatgt ctcagattgc 1400

 gaatgtgaaa aaggatatga ttattttgga gaagagtgaa ttttcagccc 1450

 tcagagcaga aaatgagaaa ataaaactcg aactacatca gttaaaacaa 1500

 caagtaatgg atgaagtgat caaagtccga acagatacca aattagactt 1550

 caacctagaa aagagcagag taaaagaatt gtattcattg aacgaaaaga 1600

 agctgctgga attgagaaca gaaatagtgg cattgcatgc ccagcaagat 1650

 cgggccctta cccagacaga caggaagatc gaaactgagg ttgctggcct 1700

 caaaaccatg cttgagtcac acaagcttga taatattaaa tatttagcag 1750

 ggtctatatt tacgtgccta acagtagctc tgggatttta tcgcctgtgg 1800

 atctaataaa gtgtctattt aaagtgaaaa aaaaaaaaaa aa 1842

<210> 6394
<211> 257
<212> PRT
<213> Homo sapien

<400> 6394
 Met Asp Cys Gly Ser Val Gly Gly Gln Arg Thr Gln Arg Leu Pro
   1               5                  10                  15

 Gly Arg Gln Arg Leu Leu Phe Leu Pro Val Gly Leu Ser Gly Arg
                  20                  25                  30

 Pro Gly Gly Ser Glu Thr Ser Ala Arg Arg Cys Pro Ser Ala Leu
                  35                  40                  45

 Ser Asp Gly Leu Gly Ala Leu Arg Pro Arg Ala Pro Ala Ala Arg
                  50                  55                  60

 Gly Gly Val Ser Arg Ala Ser Pro Leu Leu Leu Leu Leu Leu Val
                  65                  70                  75

 Pro Ser Pro Arg Leu Ala Ala Ala Ala Pro Arg Arg Gln Leu Gly
                  80                  85                  90

 Asp Trp Glu Arg Ser Arg Leu Gly Tyr Ala Ala Pro Pro Ala Gly
                  95                 100                 105

 Arg Ser Gly Ala Trp Arg Cys Ser Pro Gly Val Ala Ala Ala Ala
                 110                 115                 120

 Gly Ala Leu Pro Gln Tyr His Gly Pro Ala Pro Ala Leu Val Ser
                 125                 130                 135

 Cys Arg Arg Glu Leu Ser Leu Ser Ala Gly Ser Leu Gln Leu Glu
                 140                 145                 150

 Arg Lys Arg Arg Asp Phe Thr Ser Ser Gly Ser Arg Lys Leu Tyr
                 155                 160                 165

 Phe Asp Thr His Ala Leu Val Cys Leu Leu Glu Asp Asn Glu Ser
                 170                 175                 180

 His Ser Phe Ile Gln Ala Gly Val Gln Trp His Ser Leu Gly Leu
                 185                 190                 195

 Leu Gln Pro Pro Pro Pro Gly Phe Lys Arg Ser Ser His Leu Ile
                 200                 205                 210

 Leu Leu Ser Ser Trp Asp Tyr Arg His Ala Pro Pro His Leu Asp
                 215                 220                 225

 Asn Phe Ser Val Phe Leu Leu Glu Thr Gly Phe His His Val Gly
                 230                 235                 240

 Gln Ala Gly Leu Lys Leu Leu Thr Ser Ser Asp Pro Pro Thr Leu
                 245                 250                 255

 Ala Ser


<210> 6395
<211> 2349
<212> DNA
<213> Homo sapien

<400> 6395
 ggaattagcc tcctcaatga aaaagaaaga gggggaggaa gaggaagaga 50

 aaagaagaag aaaaccctga acatggtttc attggatatt cacccgaact 100

 gctacagaac aacacgctgc ccgattacag cccgggggaa tcttttttca 150

 ctgtctttgg ggttttcttc ccagcggcta caggagtcat ggccggttca 200

 acatgggggg cgacctcagg gagcctgccg ccagcattcc cctgggctcc 250

 ctggcagctg ttggcatctc gtggtttctg tacatcgtct tcgtcttcct 300

 cctgggcgcc atctgcactc gagaggccct tcgctatgac ttcctgatag 350

 cggaaaaggt atccctcatg ggcttcctgt tccttttggg cttatacatc 400

 tcgtccctgg cttcctgcat gggaggactt tatggagctc cccgcatcct 450

 gcagtgcatt gcccaggaga aagtgatccc tgcacttgcc tgtctgggac 500

 aagggaaggg gccaaacaaa acacccgtgg ctgccatctg cctgaccagc 550

 ttggtgacca tggcctttgt ttttgtgggt caagtgaacg ttctggcccc 600

 catcgtcacc atcaacttca tgcttgacat acgttgcagt ggactactct 650

 tacttctccc tgtccatgtg ttcctgcagc ctgaccccgg tgcctgagcc 700

 ggtgctcagg gagggcgcag aaggcctcca ctgctctgag cacctgctct 750

 tagagaaagc tcccagttac ggctctgagg gacctgccca aagagtcttg 800

 gagggcacgc tactggaatt caccaaggac atggatcagc tcctccagct 850

 aaccaggaag cttgagagta gccagcccag gcaaggagat ggtaacagga 900

 ccccagaaag tcagaagagg aaaagcaaga aggccaccaa gcagacccta 950

 caagatagct tcctcttgga cctcaaatcc cctccttctt tccctgtcga 1000

 gatctctgac aggttgcccg ctgcctcctg ggaggggcag gagtcctgct 1050

 ggaacaagca gacttccaag agcgaaggga ctcagcctga gggaacatat 1100

 ggagagcaac ttgttcctga gctgtgcaac caatcagagt ccagtggaga 1150

 agatttcttc ctgaagtcca ggctccaaga acaagatgtc tggagaagat 1200

 ccacttcttt ctatacccac atgtgcaacc cctgggtctc cctgttgggg 1250

 gctgttgggt cccttctcat catgtttgtg atacagtggg tgtataccct 1300

 ggttaacatg ggtgttgctg ccatcgtgta tttctacatt ggccgggcca 1350

 gtccagggct tcaccttgga tcagcctcca acttcagctt tttccggtgg 1400

 atgaggtctc tcttgctccc ctcctgcagg agcttgcagt ccccccagga 1450

 gcagatcatc ttggcgccgt ccctggctaa ggttgacatg gagatgactc 1500

 agctcaccca ggagaatgca gacttcgcca ctcgggatcg ctaccaccac 1550

 tcctccctcg tgaaccggga gcagctgatg cctcactact agatgcagtg 1600

 ctgggacctt cctcttttgg agctgtccca tgtacagtgg acccaagccc 1650

 aggaccttcg tggagctgct tctccaacct gagaaactca agacccatcc 1700

 tcccgctgtc actttggaca atggaaatct acattttctt ttcccttttt 1750

 ttttttttga gacagagtct cgccttgtca cccaggctgg agtccagtgg 1800

 cacaatcttg gctcactgca acctctgctt cccgagttca agcaattctc 1850

 ctgcctcagc tctgagtagc tgggattata ggcatgcacc accaccaccc 1900

 agctattttt tgtattttta ctggagacag ggtttcacca tgttggccag 1950

 gctggtctcg aactcctgac ctcgtgatcc acccgtctca gcctcccaaa 2000

 gtactgggat tacaggcgtg agccaccatg cctggccaga aatctatgtt 2050

 ttcttagaac atgtggaaga aggaaaaaga caaaaaggaa gtctggattc 2100

 tgaggaccac gtctcaccca gggtgacatc aggaatggtg ctagcctctg 2150

 caacacgaca cccagtttga agagctctat acaggtacta agactagcag 2200

 gggacaccaa gactctgcac aaccagattg cttgtgcaga gggccacaat 2250

 aagtgtatgt tttatatttt attgtattat ttattcaaaa ataaataata 2300

 cactcacatg tttccacacc caaaaaaaaa aaaaaaaaaa aaaaaaaaa 2349

<210> 6396
<211> 308
<212> PRT
<213> Homo sapien

<400> 6396
 Met Cys Ser Cys Ser Leu Thr Pro Val Pro Glu Pro Val Leu Arg
   1               5                  10                  15

 Glu Gly Ala Glu Gly Leu His Cys Ser Glu His Leu Leu Leu Glu
                  20                  25                  30

 Lys Ala Pro Ser Tyr Gly Ser Glu Gly Pro Ala Gln Arg Val Leu
                  35                  40                  45

 Glu Gly Thr Leu Leu Glu Phe Thr Lys Asp Met Asp Gln Leu Leu
                  50                  55                  60

 Gln Leu Thr Arg Lys Leu Glu Ser Ser Gln Pro Arg Gln Gly Asp
                  65                  70                  75

 Gly Asn Arg Thr Pro Glu Ser Gln Lys Arg Lys Ser Lys Lys Ala
                  80                  85                  90

 Thr Lys Gln Thr Leu Gln Asp Ser Phe Leu Leu Asp Leu Lys Ser
                  95                 100                 105

 Pro Pro Ser Phe Pro Val Glu Ile Ser Asp Arg Leu Pro Ala Ala
                 110                 115                 120

 Ser Trp Glu Gly Gln Glu Ser Cys Trp Asn Lys Gln Thr Ser Lys
                 125                 130                 135

 Ser Glu Gly Thr Gln Pro Glu Gly Thr Tyr Gly Glu Gln Leu Val
                 140                 145                 150

 Pro Glu Leu Cys Asn Gln Ser Glu Ser Ser Gly Glu Asp Phe Phe
                 155                 160                 165

 Leu Lys Ser Arg Leu Gln Glu Gln Asp Val Trp Arg Arg Ser Thr
                 170                 175                 180

 Ser Phe Tyr Thr His Met Cys Asn Pro Trp Val Ser Leu Leu Gly
                 185                 190                 195

 Ala Val Gly Ser Leu Leu Ile Met Phe Val Ile Gln Trp Val Tyr
                 200                 205                 210

 Thr Leu Val Asn Met Gly Val Ala Ala Ile Val Tyr Phe Tyr Ile
                 215                 220                 225

 Gly Arg Ala Ser Pro Gly Leu His Leu Gly Ser Ala Ser Asn Phe
                 230                 235                 240

 Ser Phe Phe Arg Trp Met Arg Ser Leu Leu Leu Pro Ser Cys Arg
                 245                 250                 255

 Ser Leu Gln Ser Pro Gln Glu Gln Ile Ile Leu Ala Pro Ser Leu
                 260                 265                 270

 Ala Lys Val Asp Met Glu Met Thr Gln Leu Thr Gln Glu Asn Ala
                 275                 280                 285

 Asp Phe Ala Thr Arg Asp Arg Tyr His His Ser Ser Leu Val Asn
                 290                 295                 300

 Arg Glu Gln Leu Met Pro His Tyr
                 305

<210> 6397
<211> 2415
<212> DNA
<213> Homo sapien

<400> 6397
 acatgctctg tgaggagatt tccctcgatg atgtgcttct gagtgctctg 50

 ctgaggaacg atgggaagtc tgcccagcag aagaaaatct ctgccaagcc 100

 caagcttgag ttcctctgtc caaggccagg gacctgtgac catggaagca 150

 gagagaagca aggccacagc cgtggccctg ggcagtttcc cggcaggtgg 200

 cccggccgag ctgtcgctga gactcgggga gccattgacc atcgtctctg 250

 aggatggaga ctggtggacg gtgctgtctg aagtctcagg cagagagtat 300

 aacatcccca gcgtccacgt ggccaaagtc tcccatgggt ggctgtatga 350

 gggcctgagc agggagaaag cagaggaact gctgttgtta cctgggaacc 400

 ctggaggggc cttcctcatc cgggagagcc agaccaggag aggctcttac 450

 tctctgtcag tccgcctcag ccgccctgca tcctgggacc ggatcagaca 500

 ctacaggatc cactgccttg acaatggctg gctgtacatc tcaccgcgcc 550

 tcaccttccc ctcactccag gccctggtgg accattactc tgagctggcg 600

 gatgacatct gctgcctact caaggagccc tgtgtcctgc agagggctgg 650

 cccgctccct ggcaaggata tacccctacc tgtgactgtg cagaggacac 700

 cactcaactg gaaagagctg gacagctccc tcctgttttc tgaagctgcc 750

 acaggggagg agtctcttct cagtgagggt ctccgggagt ccctcagctt 800

 ctacatcagc ctgaatgacg aggctgtctc tttggatgat gcctaggccc 850

 aaaggagagg ccaaaaggga aaccaaggct gcacacctag aaccccaatt 900

 cagcctcctg ggcaccccag aggcaaggct gtgcactcag ggagggaggg 950

 tgggacacag aggtgcatct agggtcccac ctgtaccctt gctctttcct 1000

 ctcttagccc ttagaagtca cctacttcct tccagtgcca tgatcccacc 1050

 tgcgacctct agtgcgagtg cagagaaggt gggaccaggg ccagggttcc 1100

 aaaaagagaa taagcctcct ggggggtctg acctagttag ttcttgagtt 1150

 tggggtttcc agtaccatct ggatgccctg cctgttgagc cccattctac 1200

 atccccacca ttaaccaggc cccacccaca aggtagaaac aacccctaga 1250

 gtcaacgaga aagtcatttt cagaaaatct acaagtctcg ttgagaccac 1300

 caccatacct cagaaggtag gactgtggcc tagaagggaa aggaaagctg 1350

 agatggtgtc ttaccgtagc agcagatctt ggatggtcca ggctctatgt 1400

 gacctccaga gcaaagagaa agactcggga cagtctaggt cctcaaatgt 1450

 cccccattga ggacaacagc cccagctctt tttctttttt ttgagacgga 1500

 gtcttgccct gttgcccatg ctggagtgca atggcacgat ctcagctcac 1550

 tgcaacctcc atctcctgga ttcaaacaat tctcctgcct cagcctccag 1600

 aatagctggg attacaggcg tacaccacca tgcctggcta atttttttgt 1650

 atttttagta gacatggggt ttcaccacat tggccaggct ggtgtcgaac 1700

 tcctgacctc aggtgatcca cccaccttgg cctcccaaag tgctgggatt 1750

 acaggtgtga gccacggcac ccagcctagc tctcagatct ctatttcatt 1800

 ttgtggctta ccattcccta gcacactggc cttgccatct tgtggccgaa 1850

 taaaaaataa cacctcttaa gtctagcaca ctgcagtgag gccaggcacc 1900

 tcagtgctgg gcaggggcat cagaaggtgc taagccctct ctccacaatg 1950

 ccaagacgga gaccacagcc tacaccaaat ccagcccttg atttccctgc 2000

 tgcctccata aacagaaaga ggtctgctgg atccgctaag ggatcaggga 2050

 gaggaagaaa gagggatggg gtgggaggca ccccctccag tgctcctact 2100

 ggttcccaag ctacaggtgg ggtgggaaag gctttatcag gtatcatcaa 2150

 caggttctca attaaagatt tgatttattc aagtatgtga aaacattcta 2200

 caatggaaac tcttattaga tgctgcatgt actgtgctat ggaccacgca 2250

 catacagcca tgctgtttca gaagacttga aatgccattg atagtttaaa 2300

 aactctacac ccgatggaga atcgaggaag acgatttaat gtttcatctg 2350

 aatccagagg tgcatcaaat taaatgacag ctccacttgg caaaaaaaaa 2400

 aaaaaaaaaa aaaaa 2415

<210> 6398
<211> 261
<212> PRT
<213> Homo sapien

<400> 6398
 Met Gly Ser Leu Pro Ser Arg Arg Lys Ser Leu Pro Ser Pro Ser
   1               5                  10                  15

 Leu Ser Ser Ser Val Gln Gly Gln Gly Pro Val Thr Met Glu Ala
                  20                  25                  30

 Glu Arg Ser Lys Ala Thr Ala Val Ala Leu Gly Ser Phe Pro Ala
                  35                  40                  45

 Gly Gly Pro Ala Glu Leu Ser Leu Arg Leu Gly Glu Pro Leu Thr
                  50                  55                  60

 Ile Val Ser Glu Asp Gly Asp Trp Trp Thr Val Leu Ser Glu Val
                  65                  70                  75

 Ser Gly Arg Glu Tyr Asn Ile Pro Ser Val His Val Ala Lys Val
                  80                  85                  90

 Ser His Gly Trp Leu Tyr Glu Gly Leu Ser Arg Glu Lys Ala Glu
                  95                 100                 105

 Glu Leu Leu Leu Leu Pro Gly Asn Pro Gly Gly Ala Phe Leu Ile
                 110                 115                 120

 Arg Glu Ser Gln Thr Arg Arg Gly Ser Tyr Ser Leu Ser Val Arg
                 125                 130                 135

 Leu Ser Arg Pro Ala Ser Trp Asp Arg Ile Arg His Tyr Arg Ile
                 140                 145                 150

 His Cys Leu Asp Asn Gly Trp Leu Tyr Ile Ser Pro Arg Leu Thr
                 155                 160                 165

 Phe Pro Ser Leu Gln Ala Leu Val Asp His Tyr Ser Glu Leu Ala
                 170                 175                 180

 Asp Asp Ile Cys Cys Leu Leu Lys Glu Pro Cys Val Leu Gln Arg
                 185                 190                 195

 Ala Gly Pro Leu Pro Gly Lys Asp Ile Pro Leu Pro Val Thr Val
                 200                 205                 210

 Gln Arg Thr Pro Leu Asn Trp Lys Glu Leu Asp Ser Ser Leu Leu
                 215                 220                 225

 Phe Ser Glu Ala Ala Thr Gly Glu Glu Ser Leu Leu Ser Glu Gly
                 230                 235                 240

 Leu Arg Glu Ser Leu Ser Phe Tyr Ile Ser Leu Asn Asp Glu Ala
                 245                 250                 255

 Val Ser Leu Asp Asp Ala
                 260

<210> 6399
<211> 794
<212> DNA
<213> Homo sapien

<400> 6399
 ggcagccgtc tgtgccaccc agagccggcg ggccgctagg tccccggaga 50

 ccctgctatg gtgcgtgcgg gcgccgtggg ggctcatctc cccgcgtccg 100

 gcttggatat cttcggggac ctgaagaaga tgaacaagcg ccagctctat 150

 taccaggttt taaacttcgc catgatcgtg tcttctgcac tcatgatatg 200

 gaaaggcttg atcgtgctca caggcagtga gagccccatc gtggtggtgc 250

 tgagtggcag tatggagccg gcctttcaca gaggagacct cctgttcctc 300

 acaaatttcc gggaagaccc aatcagagct ggtgaaatag ttgtttttaa 350

 agttgaagga cgagacattc caatagttca cagagtaatc aaagttcatg 400

 aaaaagataa tggagacatc aaatttctga ctaaaggaga taataatgaa 450

 gttgatgata gaggcttgta caaagaaggc cagaactggc tggaaaagaa 500

 ggacgtggtg ggaagagcaa gagggttttt accatatgtt ggtatggtca 550

 ccataataat gaatgactat ccaaaattca agtatgctct tttggctgta 600

 atgggtgcat atgtgttact aaaacgtgaa tcctaaaatg agaagcagtt 650

 cctgggacca gattgaaatg aattctgttg aaaaagagaa aaactaatat 700

 atttgagatg ttccattttc tgtataaaag ggaacagtgt ggagatgttt 750

 ttgtcttgtc caaataaaag attcaccagt aaaaaaaaaa aaaa 794

<210> 6400
<211> 192
<212> PRT
<213> Homo sapien

<400> 6400
 Met Val Arg Ala Gly Ala Val Gly Ala His Leu Pro Ala Ser Gly
   1               5                  10                  15

 Leu Asp Ile Phe Gly Asp Leu Lys Lys Met Asn Lys Arg Gln Leu
                  20                  25                  30

 Tyr Tyr Gln Val Leu Asn Phe Ala Met Ile Val Ser Ser Ala Leu
                  35                  40                  45

 Met Ile Trp Lys Gly Leu Ile Val Leu Thr Gly Ser Glu Ser Pro
                  50                  55                  60

 Ile Val Val Val Leu Ser Gly Ser Met Glu Pro Ala Phe His Arg
                  65                  70                  75

 Gly Asp Leu Leu Phe Leu Thr Asn Phe Arg Glu Asp Pro Ile Arg
                  80                  85                  90

 Ala Gly Glu Ile Val Val Phe Lys Val Glu Gly Arg Asp Ile Pro
                  95                 100                 105

 Ile Val His Arg Val Ile Lys Val His Glu Lys Asp Asn Gly Asp
                 110                 115                 120

 Ile Lys Phe Leu Thr Lys Gly Asp Asn Asn Glu Val Asp Asp Arg
                 125                 130                 135

 Gly Leu Tyr Lys Glu Gly Gln Asn Trp Leu Glu Lys Lys Asp Val
                 140                 145                 150

 Val Gly Arg Ala Arg Gly Phe Leu Pro Tyr Val Gly Met Val Thr
                 155                 160                 165

 Ile Ile Met Asn Asp Tyr Pro Lys Phe Lys Tyr Ala Leu Leu Ala
                 170                 175                 180

 Val Met Gly Ala Tyr Val Leu Leu Lys Arg Glu Ser
                 185                 190

<210> 6401
<211> 4644
<212> DNA
<213> Homo sapien

<400> 6401
 agccaagccc agcagagtgg ccccactggc cagccgagcc agcccccagg 50

 cacagccacc acgccactgg agggtgacgg cctctccgcg cccaccgagg 100

 ttggcgacag ccccctgcag gcccaggctt tgggagaggc aggagtggcc 150

 acaggaagtg aggctcagag cagcccgcaa ttccaggacc acacggaagg 200

 ggaggaccag gacgcttcca tcccctctgg gggcagaggc ctgtcccagg 250

 aggggaccgg tccccccacc tctgctggtg aaggccattc taggactgaa 300

 gatgctgccc aggagctcct gttgcctgag tcaaaaggag gcagctctga 350

 gcccgggaca gaactgcaga ccaccgagca acaggcaggg gcctcagcct 400

 ctatggcagt tgatgctgta gctgagccag ccaatgcagt taaaggggcc 450

 gggaaggaaa tgaaagagaa gacccagaga atgaaacagc caccagcaac 500

 cactcctcct ttcaaaacac actgccagga agctgagacc aagaccaagg 550

 acgagatggc tgctgctgaa gaaaaagtcg gtaagaatga acaaggggag 600

 cctgaagacc tcaagaagcc agaggggaag aacagaagtg cagctgctgt 650

 gaaaaacgag aaggagcaaa aaaaccagga agcagatgtc caggaagtga 700

 aggcaagcac gctgagcccg ggtggaggag tcaccgtgtt cttccacgcc 750

 atcatctctc ttcatttccc attcaatcct gacctccata aagtcttcat 800

 cagaggagga gaagaatttg gggagtcaaa atgggacagc aatatctgtg 850

 agctgcacta caccagagac ttgggtcatg accgcgttct tgttgaaggc 900

 attgtctgca tttccaagaa gcacctagat aaatacattc cttacaagta 950

 cgtcatttat aatggggaat cttttgagta tgagttcatt tacaagcacc 1000

 agcagaagaa gggcgagtac gtcaaccgct gtctgttcat aaaatcttca 1050

 cttctgggct caggagactg gcatcagtac tatgacatag tttatatgaa 1100

 gcctcatggg agactccaga aagtcatgaa ccacatcaca gacgggccga 1150

 ggaaggacct ggtgaagggg aagcagattg ccgctgcgct catgctggac 1200

 agcaccttca gcatcctgca gacctgggac accatcaacc tgaacagctt 1250

 cttcacccag ttcgagcagt tttgctttgt cctgcaacag cctatgattt 1300

 atgaaggaca ggcacagctg tggaccgatt tgcagtacag ggagaaagag 1350

 gtgaagagat acctgtggca acatctgaaa aaacacgtgg taccattgcc 1400

 ggacggaaaa agcacggact ttttgcctgt ggactgccca gtgaggagta 1450

 aactgaaaac aggcctgatt gtcctttttg tagtggaaaa aattgagctt 1500

 ttattagaag gcagcctgga ctggttgtgt cacctcctaa cctcagatgc 1550

 cagctcacca gatgagtttc accgtgacct aagccacatc cttgggatac 1600

 ctcagagctg gcggctgtac ctggtgaacc tgtgccaaag atgcatggac 1650

 acaaggacgt acacctggct gggcgccctg cctgtcctgc actgctgtat 1700

 ggagctggcc ccgcggcaca aggatgcctg gagacagcct gaggacacct 1750

 gggccgctct ggagggactc tccttctcac cgttccggga acaaatgcta 1800

 gatacgagtt ccctacttca gtttatgaga gagaagcagc atttgctgag 1850

 catagacgag cctctcttcc ggtcctggtt tagtctgcta cctctgagtc 1900

 acctggttat gtatatggaa aacttcattg agcacctggg tcgttttcct 1950

 gctcatatcc tggactgtct ttcagggatt tactaccggc ttccgggact 2000

 tgagcaagtc ttgaatacgc aggatgttca ggatgttcag aacgttcaga 2050

 acattttaga aatgctgttg cgactcctgg acacttaccg ggacaagatt 2100

 cccgaggagg ccttgtcacc atcctacctg actgtgtgtc tgaaactgca 2150

 tgaagccatc tgcagcagca caaagctact taagttttac gagctgccag 2200

 ccttatctgc cgagattgtc tgcagaatga ttagacttct atctctggtg 2250

 gattctgcag gacagagaga tgaaactgga aataattcag tccaaacagt 2300

 cttccaaggg acccttgctg ctacgaaaag gtggctccga gaagttttta 2350

 caaagaacat gctcacatct tcaggtgcct cattcacata cgtcaaggaa 2400

 attgaggtct ggaggcggct ggtggaaatc caattccccg cggagcatgg 2450

 ctggaaggag tcgttgctgg gagacatgga atggaggctc acaaaggagg 2500

 aacccctctc ccagatcact gcctactgca atagttgctg ggacaccaaa 2550

 ggcttagagg acagtgtggc caagaccttc gagaaatgca tcattgaagc 2600

 cgtgagctca gcctgccagt ctcagaccag tatccttcag gggttctctt 2650

 actctgattt gcggaaattt ggcatcgtct tgtctgctgt gatcactaag 2700

 tcctggccta ggaccgcgga caacttcgat gacattttaa agcatctgct 2750

 cacgttggca gatgtcaagc acgtcttcag attgtgtgga accgacgaga 2800

 aaatactagc aaatgtcaca gaggatgcca agaggctgat agctgttgcc 2850

 gactctgtgt tgacgaaagt tgttggtgac ctcctaagtg gcacgatttt 2900

 agttggacaa ctggagctga ttataaagca caagaatcag tttcttgaca 2950

 tctggcaact gagggaaaaa agtctttcac cccaggatga aaaatgtgct 3000

 gtggaggaag cactggattg gagaagggag gaactgttac ttctaaagaa 3050

 agagaaaaga tgtgttgata gtctcctgaa gatgtgtggg aacgtgaaac 3100

 atctgataca agtggacttt ggagtgcttg cagtaagaca ctcacaagac 3150

 ctcagcagta aaagattaaa tgacaccatg acagtgagac tgtccacctc 3200

 ctcgaactcg cagagggcaa cgcattacca cctgagctcc caggtccaag 3250

 aaatggctgg gaagatagac ttgctcagag acagccacat cttccagctc 3300

 ttctggcggg aagccgcaga gccgctgagt gagcctaagg aggaccagga 3350

 agccgcagag ttgctgagtg agcccgaaga agaatcagaa aggcacatcc 3400

 ttgagcttca agaggtgtat gactatttgt atcagccttc ttacagaaag 3450

 ttcattaagt tgcaccagga tctaaagtca ggagaggtca cccttgcaga 3500

 gattgatgtc atcttcaagg actttgtgaa taaatacacg gacctggatt 3550

 cagaacttaa gatcatgtgc accgtggacc accagggcca aagagattgg 3600

 atcaaggacc gagtggaaca gatcaaggaa taccatcacc tgcaccaggc 3650

 tgtccacgca gccaaggtca tcttgcaggt caaagagagc ctgggactga 3700

 acggtgactt cagtgttctc aacactttac taaattttac tgataacttc 3750

 gacgactttc gccgtgaaac actggaccag atcaaccagg agctcatcca 3800

 ggccaaaaag ctgctccagg acatcagcga ggcccggtgc aaggggctgc 3850

 aggctctgtc cctgagaaag gagttcatct gctgggtccg ggaggctctt 3900

 ggaggcatca atgagctgaa ggtgtttgtg gacctggcct ccatctcagc 3950

 gggggagaat gacattgatg tggaccgggt ggcctgcttc catgacgctg 4000

 tgcagggcta cgcatccctg ctatttaagc tggaccccag cgtggacttc 4050

 agtgcattca tgaagcatct gaaaaagctg tggaaggctc tggataagga 4100

 ccagtacctg cccaggaaac tggtgagtct tattctgtct ctaatgcaga 4150

 ttttgttgaa tagagcattg cttagcaacg ttagggcagt gactgtggaa 4200

 atggtggcac acctgtgtgg taggtttgta cacagccgtt ttcaatgata 4250

 tttaaaaagc ttttcttcat aaatggaaat tcaccatctt gttacctaga 4300

 aagcaggata caaaattaca tgacacatag taatctctaa ggtgcaaaac 4350

 acacgtggaa aaaagacaga agggaaatat gctgaaacgt tgccaggagt 4400

 tttctctgaa tggttgtaat tgtcatttta ttctgttact ttttgttatt 4450

 ttctataatt gatagaattt tttatcagaa aaaagtaaac atttaaaatt 4500

 agccaggcat ggtggtgtgc gcctgtaatc ccagctactc tggaggctga 4550

 gacagaattg cttgaacccg ggaggcagag atagcagtga actgagatca 4600

 caccactgta ctccagcctg agtgacaaag tgagactctg tctc 4644

<210> 6402
<211> 3243
<212> DNA
<213> Homo sapien

<400> 6402
 gggcttcgtg ttcctgggtg ctgaccgtgc actccccgcc gcccgaggac 50

 ttagagctct ggaagtagct ctccagcttc cttcgtactc gggggccgga 100

 cttgtacacc cgcacgagga gcggggacgg cgggcgcaga agtgggccac 150

 catatctgga aactacagtc tatgctttga agcgcaaaag ggaataaaca 200

 tttaaagact cccccgggga cctggaggat ggacttttcc atggtggccg 250

 gagcagcagc ttacaatgaa aaatcaggta ggattacctc gctctcactc 300

 ttgtttcaga aagtctttgc tcagatcttt cctcagtgga gaaaggggaa 350

 tacagaagaa tgtctcccct acaagtgctc agagactggt gctcttggag 400

 aaaactatag ttggcaaatt cccattaacc acaatgactt caaaatttta 450

 aaaaataatg agcgtcagct gtgtgaagtc ctccagaata agtttggctg 500

 tatctctacc ctggtctctc cagttcagga aggcaacagc aaatctctgc 550

 aagtgttcag aaaaatgctg actcctagga tagagttatc agtctggaaa 600

 gatgacctca ccacacatgc tgttgatgct gtggtgaatg cagccaatga 650

 agatcttctg catgggggag gcctggccct ggccctggta aaagctggtg 700

 gatttgaaat ccaagaagag agcaaacagt ttgttgccag atatggtaaa 750

 gtgtcagctg gtgagatagc tgtcacggga gcagggaggc ttccctgcaa 800

 acagatcatc catgctgttg ggcctcggtg gatggaatgg gataaacagg 850

 gatgtactgg aaagctgcag agggccattg taagtattct gaattatgtc 900

 atctataaaa atactcacat taagacagta gcaattccag ccttgagctc 950

 tgggattttt cagttccctc tgaatttgtg tacaaagact attgtagaga 1000

 ctatccgggt tagtttgcaa gggaagccaa tgatgagtaa tttgaaagaa 1050

 attcacctgg tgagcaatga ggaccctact gttgctgcct ttaaagctgc 1100

 ttcagaattc atcctaggga agagtgagct gggacaagaa accacccctt 1150

 ctttcaatgc aatggtcgtg aacaacctga ccctccagat tgtccagggc 1200

 cacattgaat ggcagacggc agatgtaatt gttaattctg taaacccaca 1250

 tgatattaca gttggacctg tggcaaagtc aattctacaa caagcaggag 1300

 ttgaaatgaa atcggaattt cttgccacaa aggctaaaca gtttcaacgg 1350

 tcccagttgg tactggtcac aaaaggattt aacttgttct gtaaatatat 1400

 ataccatgta ctgtggcatt cagaatttcc taaacctcag atattaaaac 1450

 atgcaatgaa ggagtgtttg gaaaaatgca ttgagcaaaa tataacttcc 1500

 atttcctttc ctgcccttgg gactggaaac atggaaataa agaaggaaac 1550

 agcagcagag attttgtttg atgaagtttt aacatttgcc aaagaccatg 1600

 taaaacacca gttaactgta aaatttgtga tctttccaac agatttggag 1650

 atatataagg ctttcagttc tgaaatggca aagaggtcca agatgctgag 1700

 tttgaacaat tacagtgtcc cccagtcaac cagagaggag aaaagagaaa 1750

 atgggcttga agctagatct cctgccatca atctgatggg attcaacgtg 1800

 gaagagatgt gtgaggccca cgcatggatc caaagaatcc tgagtctcca 1850

 gaaccaccac atcattgaga ataatcatat tctgtacctt gggagaaagg 1900

 aacatgacat tttgtctcag cttcagaaaa cttcaagtgt ctccatcaca 1950

 gaaattatca gcccaggaag gacagagtta gagattgaag gagcccgggc 2000

 tgacctcatt gaggtggtta tgaacattga agatatgctt tgtaaagtac 2050

 aggaggaaat ggcaaggaaa aaggagcgag gcctttggcg ctcgttagga 2100

 cagtggacta ttcagcaaca aaaaacccaa gacgaaatga aagaaaatat 2150

 catatttctg aaatgtcctg tgcctccaac tcaagagctt ctagatcaaa 2200

 agaaacagtt tgaaaaatgt ggtttgcagg ttctaaaggt ggagaagata 2250

 gacaatgagg tccttatggc tgcctttcaa agaaagaaga aaatgatgga 2300

 agaaaaactg cacaggcaac ctgtgagcca taggctgttt cagcaagtcc 2350

 cataccagtt ctgcaatgtg gtatgcagag ttggctttca aagaatgtac 2400

 tcgacacctt gcgatccaaa atacggagct ggcatatact tcaccaagaa 2450

 cctcaaaaac ctggcagaga aggccaagaa aatctctgct gcagataagc 2500

 tgatctatgt gtttgaggct gaagtactca caggcttctt ctgccaggga 2550

 catccgttaa atattgttcc cccaccactg agtcctggag ctatagatgg 2600

 tcatgacagt gtggttgaca atgtctccag ccctgaaacc tttgttattt 2650

 ttagtggcat gcaggctata cctcagtatt tgtggacatg cacccaggaa 2700

 tatgtacagt cacaagatta ctcatcagga ccaatgagac cctttgcaca 2750

 gcatccttgg aggggattcg caagtggcag ccctgttgat taatctctac 2800

 atcattttaa cagctggtat ggccttacct tgggtgaact aaccaaataa 2850

 tgaccatcga tggctcaaag agtggcttga atatatccca tgggttatct 2900

 gtatggactg actgggttat tgaaaggact agccacatac tagcatctta 2950

 gtgcctttat ctgtctttat gtcttggggt tggggtaggt agataccaaa 3000

 tgaaacactt tcaggacctt ccttcctctt gcagttgttc tttaatctcc 3050

 tttactagag gagataaata ttttgcatat aatgaagaaa tttttctagt 3100

 atataacgca ggccttttat tttctaaaat gatgatagta taaaaatgtt 3150

 aggataacag aatgatttta gattttccag agaatattat aaagtgcttt 3200

 aggtatgaaa ataaatcatc tttgtctgat taaaaaaaaa aaa 3243

<210> 6403
<211> 854
<212> PRT
<213> Homo sapien

<400> 6403
 Met Asp Phe Ser Met Val Ala Gly Ala Ala Ala Tyr Asn Glu Lys
   1               5                  10                  15

 Ser Gly Arg Ile Thr Ser Leu Ser Leu Leu Phe Gln Lys Val Phe
                  20                  25                  30

 Ala Gln Ile Phe Pro Gln Trp Arg Lys Gly Asn Thr Glu Glu Cys
                  35                  40                  45

 Leu Pro Tyr Lys Cys Ser Glu Thr Gly Ala Leu Gly Glu Asn Tyr
                  50                  55                  60

 Ser Trp Gln Ile Pro Ile Asn His Asn Asp Phe Lys Ile Leu Lys
                  65                  70                  75

 Asn Asn Glu Arg Gln Leu Cys Glu Val Leu Gln Asn Lys Phe Gly
                  80                  85                  90

 Cys Ile Ser Thr Leu Val Ser Pro Val Gln Glu Gly Asn Ser Lys
                  95                 100                 105

 Ser Leu Gln Val Phe Arg Lys Met Leu Thr Pro Arg Ile Glu Leu
                 110                 115                 120

 Ser Val Trp Lys Asp Asp Leu Thr Thr His Ala Val Asp Ala Val
                 125                 130                 135

 Val Asn Ala Ala Asn Glu Asp Leu Leu His Gly Gly Gly Leu Ala
                 140                 145                 150

 Leu Ala Leu Val Lys Ala Gly Gly Phe Glu Ile Gln Glu Glu Ser
                 155                 160                 165

 Lys Gln Phe Val Ala Arg Tyr Gly Lys Val Ser Ala Gly Glu Ile
                 170                 175                 180

 Ala Val Thr Gly Ala Gly Arg Leu Pro Cys Lys Gln Ile Ile His
                 185                 190                 195

 Ala Val Gly Pro Arg Trp Met Glu Trp Asp Lys Gln Gly Cys Thr
                 200                 205                 210

 Gly Lys Leu Gln Arg Ala Ile Val Ser Ile Leu Asn Tyr Val Ile
                 215                 220                 225

 Tyr Lys Asn Thr His Ile Lys Thr Val Ala Ile Pro Ala Leu Ser
                 230                 235                 240

 Ser Gly Ile Phe Gln Phe Pro Leu Asn Leu Cys Thr Lys Thr Ile
                 245                 250                 255

 Val Glu Thr Ile Arg Val Ser Leu Gln Gly Lys Pro Met Met Ser
                 260                 265                 270

 Asn Leu Lys Glu Ile His Leu Val Ser Asn Glu Asp Pro Thr Val
                 275                 280                 285

 Ala Ala Phe Lys Ala Ala Ser Glu Phe Ile Leu Gly Lys Ser Glu
                 290                 295                 300

 Leu Gly Gln Glu Thr Thr Pro Ser Phe Asn Ala Met Val Val Asn
                 305                 310                 315

 Asn Leu Thr Leu Gln Ile Val Gln Gly His Ile Glu Trp Gln Thr
                 320                 325                 330

 Ala Asp Val Ile Val Asn Ser Val Asn Pro His Asp Ile Thr Val
                 335                 340                 345

 Gly Pro Val Ala Lys Ser Ile Leu Gln Gln Ala Gly Val Glu Met
                 350                 355                 360

 Lys Ser Glu Phe Leu Ala Thr Lys Ala Lys Gln Phe Gln Arg Ser
                 365                 370                 375

 Gln Leu Val Leu Val Thr Lys Gly Phe Asn Leu Phe Cys Lys Tyr
                 380                 385                 390

 Ile Tyr His Val Leu Trp His Ser Glu Phe Pro Lys Pro Gln Ile
                 395                 400                 405

 Leu Lys His Ala Met Lys Glu Cys Leu Glu Lys Cys Ile Glu Gln
                 410                 415                 420

 Asn Ile Thr Ser Ile Ser Phe Pro Ala Leu Gly Thr Gly Asn Met
                 425                 430                 435

 Glu Ile Lys Lys Glu Thr Ala Ala Glu Ile Leu Phe Asp Glu Val
                 440                 445                 450

 Leu Thr Phe Ala Lys Asp His Val Lys His Gln Leu Thr Val Lys
                 455                 460                 465

 Phe Val Ile Phe Pro Thr Asp Leu Glu Ile Tyr Lys Ala Phe Ser
                 470                 475                 480

 Ser Glu Met Ala Lys Arg Ser Lys Met Leu Ser Leu Asn Asn Tyr
                 485                 490                 495

 Ser Val Pro Gln Ser Thr Arg Glu Glu Lys Arg Glu Asn Gly Leu
                 500                 505                 510

 Glu Ala Arg Ser Pro Ala Ile Asn Leu Met Gly Phe Asn Val Glu
                 515                 520                 525

 Glu Met Cys Glu Ala His Ala Trp Ile Gln Arg Ile Leu Ser Leu
                 530                 535                 540

 Gln Asn His His Ile Ile Glu Asn Asn His Ile Leu Tyr Leu Gly
                 545                 550                 555

 Arg Lys Glu His Asp Ile Leu Ser Gln Leu Gln Lys Thr Ser Ser
                 560                 565                 570

 Val Ser Ile Thr Glu Ile Ile Ser Pro Gly Arg Thr Glu Leu Glu
                 575                 580                 585

 Ile Glu Gly Ala Arg Ala Asp Leu Ile Glu Val Val Met Asn Ile
                 590                 595                 600

 Glu Asp Met Leu Cys Lys Val Gln Glu Glu Met Ala Arg Lys Lys
                 605                 610                 615

 Glu Arg Gly Leu Trp Arg Ser Leu Gly Gln Trp Thr Ile Gln Gln
                 620                 625                 630

 Gln Lys Thr Gln Asp Glu Met Lys Glu Asn Ile Ile Phe Leu Lys
                 635                 640                 645

 Cys Pro Val Pro Pro Thr Gln Glu Leu Leu Asp Gln Lys Lys Gln
                 650                 655                 660

 Phe Glu Lys Cys Gly Leu Gln Val Leu Lys Val Glu Lys Ile Asp
                 665                 670                 675

 Asn Glu Val Leu Met Ala Ala Phe Gln Arg Lys Lys Lys Met Met
                 680                 685                 690

 Glu Glu Lys Leu His Arg Gln Pro Val Ser His Arg Leu Phe Gln
                 695                 700                 705

 Gln Val Pro Tyr Gln Phe Cys Asn Val Val Cys Arg Val Gly Phe
                 710                 715                 720

 Gln Arg Met Tyr Ser Thr Pro Cys Asp Pro Lys Tyr Gly Ala Gly
                 725                 730                 735

 Ile Tyr Phe Thr Lys Asn Leu Lys Asn Leu Ala Glu Lys Ala Lys
                 740                 745                 750

 Lys Ile Ser Ala Ala Asp Lys Leu Ile Tyr Val Phe Glu Ala Glu
                 755                 760                 765

 Val Leu Thr Gly Phe Phe Cys Gln Gly His Pro Leu Asn Ile Val
                 770                 775                 780

 Pro Pro Pro Leu Ser Pro Gly Ala Ile Asp Gly His Asp Ser Val
                 785                 790                 795

 Val Asp Asn Val Ser Ser Pro Glu Thr Phe Val Ile Phe Ser Gly
                 800                 805                 810

 Met Gln Ala Ile Pro Gln Tyr Leu Trp Thr Cys Thr Gln Glu Tyr
                 815                 820                 825

 Val Gln Ser Gln Asp Tyr Ser Ser Gly Pro Met Arg Pro Phe Ala
                 830                 835                 840

 Gln His Pro Trp Arg Gly Phe Ala Ser Gly Ser Pro Val Asp
                 845                 850

<210> 6404
<211> 2444
<212> DNA
<213> Homo sapien

<400> 6404
 ggctccgggg gtggcggtcg gacagtgtct agcacgctca gtccgggctt 50

 ggggccccgc ggcggagaag gaggtagagg gggcggcggc ggcggcggcg 100

 gtggtggcgg caccatgttt cttcactcag ttaatctctg gaacctggcg 150

 ttttatgtct tcatggtctt tctggcaacc ctggggctgt gggatgtctt 200

 cttcggcttc gaggagaata agtgcagtat gagctacatg tttgagtacc 250

 cggagtatca gaaaatagaa cttccaaaga aactggcaaa acgctatccc 300

 gcatatgagt tgtatcttta tggagaggga tcctatgctg aagaacacaa 350

 aattctccct ttgacgggta ttccagttct ctttcttcct ggtaatgctg 400

 gaagttataa gcaagttcgt tctattggct ccattgcact tagaaaagca 450

 gaggacattg acttcaagta ccactttgac ttctttagtg tgaacttcaa 500

 tgaagaactg gtggctttgt atggtggaag tcttcagaag cagaccaagt 550

 ttgtacatga atgtattaaa acaattctca aactctataa gggtcaagaa 600

 tttgctccaa aaagtgtggc aataattggt cattctatgg gtggccttgt 650

 tgcaagagca ttgcttacac tgaaaaattt taagcatgat ctgataaatc 700

 ttcttattac acaagccaca cctcatgttg ctcctgtgat gccattagat 750

 cgtttcatta cagattttta tacgactgta aacaactatt ggattctaaa 800

 tgctcgacac ataaatttaa ccacactttc tgtagctgga ggattccggg 850

 attaccaagt tcgttcagga ttgacttttc taccaaaatt aagccatcat 900

 accagtgcct tatctgttgt gagttcagca gtgcctaaga cctgggtctc 950

 aacagaccac ctctccattg tgtggtgtaa acaattgcag ttgactacag 1000

 ttcgagcatt ctttgatctt attggtgctg atactaaaca aataactcaa 1050

 aattccaaga agaaactgtc agttttgtat caccacttta taagacaccc 1100

 atcaaaacat tttgaggaaa atccagctat aatttctgac ttaacaggga 1150

 catctatgtg ggttctagta aaagtgtcca aatggaccta tgtagcttac 1200

 aacgaatctg agaagatata ttttacattt cctcttgaaa atcatagaaa 1250

 aatctacact catgtctatt gtcagagcac tatgctggat acaaatagtt 1300

 ggatttttgc ttgcataaac agcacttcta tgtgcctgca aggggttgat 1350

 ttatcatgga aagctgaact gctgccaaca attaagtatc tgacattaag 1400

 acttcaagac tatccatctt tgtctcatct tgttgtttat gtaccatctg 1450

 ttcgtggaag taagtttgtt gtagattgtg aattctttaa aaaagagaaa 1500

 agatacatac agcttcctgt aactcatctt ttttcctttg gattgtcttc 1550

 aaggaaagtg gtgttaaata caaatggcct atactacaat ctagagcttc 1600

 tgaactttgg acagatatac caagctttta aaatcaacgt ggtaagcaag 1650

 tgctcagcag tcaaagaaga aataaccagt atctatagac ttcatattcc 1700

 ttggtcttat gaagattcac taaccattgc acaggctcca tcttccacag 1750

 aaatttctct gaaactccat attgctcaac cagaaaacaa tacccatgtg 1800

 gcattattta aaatgtacac gtcatcagac tgtcggtacg aggtgacagt 1850

 taagacttcc ttttcacaaa tacttggaca ggttgttgct tagaatatgc 1900

 taccatgttg gataaagaag ccaaaccata caaagttgat ccttttgtaa 1950

 ttatcattaa gtttctgttg gggtaagttt tattatctgt gataatgatt 2000

 ttaattgtgt tttacatgta acattatatt tggttccata atgcaatata 2050

 aattttcata cagatttggc agttgacttg tttcattaaa tgaggttttt 2100

 ttttttctct taggcaaagg tctaataagt atatcaatgt ctacttcaat 2150

 agtatcattt caaaagtaat tattcacttt atgtatatca gtctaaactt 2200

 agactgcctt taatgtttgt aaataggtgt atatggtcca tgatctgtga 2250

 gtatcctaga ttcaaacgca aatcattaca gggtattgat gaaacagtgc 2300

 ctctctgatc acttttaaaa gtatatttta gacctctcta ccctagttaa 2350

 cattccattc ttaatttagt cacattttca gatttttggt taagcatcaa 2400

 tatgtagatc tttttttcca tcattacaac taacttggct ttct 2444

<210> 6405
<211> 592
<212> PRT
<213> Homo sapien

<400> 6405
 Met Phe Leu His Ser Val Asn Leu Trp Asn Leu Ala Phe Tyr Val
   1               5                  10                  15

 Phe Met Val Phe Leu Ala Thr Leu Gly Leu Trp Asp Val Phe Phe
                  20                  25                  30

 Gly Phe Glu Glu Asn Lys Cys Ser Met Ser Tyr Met Phe Glu Tyr
                  35                  40                  45

 Pro Glu Tyr Gln Lys Ile Glu Leu Pro Lys Lys Leu Ala Lys Arg
                  50                  55                  60

 Tyr Pro Ala Tyr Glu Leu Tyr Leu Tyr Gly Glu Gly Ser Tyr Ala
                  65                  70                  75

 Glu Glu His Lys Ile Leu Pro Leu Thr Gly Ile Pro Val Leu Phe
                  80                  85                  90

 Leu Pro Gly Asn Ala Gly Ser Tyr Lys Gln Val Arg Ser Ile Gly
                  95                 100                 105

 Ser Ile Ala Leu Arg Lys Ala Glu Asp Ile Asp Phe Lys Tyr His
                 110                 115                 120

 Phe Asp Phe Phe Ser Val Asn Phe Asn Glu Glu Leu Val Ala Leu
                 125                 130                 135

 Tyr Gly Gly Ser Leu Gln Lys Gln Thr Lys Phe Val His Glu Cys
                 140                 145                 150

 Ile Lys Thr Ile Leu Lys Leu Tyr Lys Gly Gln Glu Phe Ala Pro
                 155                 160                 165

 Lys Ser Val Ala Ile Ile Gly His Ser Met Gly Gly Leu Val Ala
                 170                 175                 180

 Arg Ala Leu Leu Thr Leu Lys Asn Phe Lys His Asp Leu Ile Asn
                 185                 190                 195

 Leu Leu Ile Thr Gln Ala Thr Pro His Val Ala Pro Val Met Pro
                 200                 205                 210

 Leu Asp Arg Phe Ile Thr Asp Phe Tyr Thr Thr Val Asn Asn Tyr
                 215                 220                 225

 Trp Ile Leu Asn Ala Arg His Ile Asn Leu Thr Thr Leu Ser Val
                 230                 235                 240

 Ala Gly Gly Phe Arg Asp Tyr Gln Val Arg Ser Gly Leu Thr Phe
                 245                 250                 255

 Leu Pro Lys Leu Ser His His Thr Ser Ala Leu Ser Val Val Ser
                 260                 265                 270

 Ser Ala Val Pro Lys Thr Trp Val Ser Thr Asp His Leu Ser Ile
                 275                 280                 285

 Val Trp Cys Lys Gln Leu Gln Leu Thr Thr Val Arg Ala Phe Phe
                 290                 295                 300

 Asp Leu Ile Gly Ala Asp Thr Lys Gln Ile Thr Gln Asn Ser Lys
                 305                 310                 315

 Lys Lys Leu Ser Val Leu Tyr His His Phe Ile Arg His Pro Ser
                 320                 325                 330

 Lys His Phe Glu Glu Asn Pro Ala Ile Ile Ser Asp Leu Thr Gly
                 335                 340                 345

 Thr Ser Met Trp Val Leu Val Lys Val Ser Lys Trp Thr Tyr Val
                 350                 355                 360

 Ala Tyr Asn Glu Ser Glu Lys Ile Tyr Phe Thr Phe Pro Leu Glu
                 365                 370                 375

 Asn His Arg Lys Ile Tyr Thr His Val Tyr Cys Gln Ser Thr Met
                 380                 385                 390

 Leu Asp Thr Asn Ser Trp Ile Phe Ala Cys Ile Asn Ser Thr Ser
                 395                 400                 405

 Met Cys Leu Gln Gly Val Asp Leu Ser Trp Lys Ala Glu Leu Leu
                 410                 415                 420

 Pro Thr Ile Lys Tyr Leu Thr Leu Arg Leu Gln Asp Tyr Pro Ser
                 425                 430                 435

 Leu Ser His Leu Val Val Tyr Val Pro Ser Val Arg Gly Ser Lys
                 440                 445                 450

 Phe Val Val Asp Cys Glu Phe Phe Lys Lys Glu Lys Arg Tyr Ile
                 455                 460                 465

 Gln Leu Pro Val Thr His Leu Phe Ser Phe Gly Leu Ser Ser Arg
                 470                 475                 480

 Lys Val Val Leu Asn Thr Asn Gly Leu Tyr Tyr Asn Leu Glu Leu
                 485                 490                 495

 Leu Asn Phe Gly Gln Ile Tyr Gln Ala Phe Lys Ile Asn Val Val
                 500                 505                 510

 Ser Lys Cys Ser Ala Val Lys Glu Glu Ile Thr Ser Ile Tyr Arg
                 515                 520                 525

 Leu His Ile Pro Trp Ser Tyr Glu Asp Ser Leu Thr Ile Ala Gln
                 530                 535                 540

 Ala Pro Ser Ser Thr Glu Ile Ser Leu Lys Leu His Ile Ala Gln
                 545                 550                 555

 Pro Glu Asn Asn Thr His Val Ala Leu Phe Lys Met Tyr Thr Ser
                 560                 565                 570

 Ser Asp Cys Arg Tyr Glu Val Thr Val Lys Thr Ser Phe Ser Gln
                 575                 580                 585

 Ile Leu Gly Gln Val Val Ala
                 590

<210> 6406
<211> 1683
<212> DNA
<213> Homo sapien

<400> 6406
 agaaacggca gtggcagcag cgtccggagc agccgcagcc ttctggaagc 50

 tccaggcggt ctttctgccg agcctcggtc ccggccccca tcctccccgc 100

 cccatcggtt gttgtctggg cggatttaaa cagtcaagta aaatcaagct 150

 gggtaatcat ggcagaaggt ggatttgatc cctgtgaatg tgtttgctct 200

 catgaacatg caatgagaag actgatcaat ctgttacggc agtcccagtc 250

 ctactgcaca gacacagagt gtcttcagga attaccggga ccctctggtg 300

 ataatggcat cagtgttaca atgatcttgg tagcctggat ggttattgca 350

 ttgatcttgt tcttactgag acctcctaat ctaagaggat ccagcctacc 400

 tggaaagcca accagtcctc ataatggaca agatccacca gctcctcctg 450

 tggactaact ttgtgatatg ggaagtgaaa atagttaaca ccttgcacga 500

 ccaaacgaac gaagatgacc agagtactct taaccccatt agaactgttt 550

 ttccttttgt atctgcaata tgggatggta ttgttttcat gagcttctag 600

 aaatttcact tgcaagttta tttttgcttc ctgtgttact gccattccta 650

 tttacagtat atttgagtga atgattatat ttttaaaaag ttacatgggg 700

 cttttttggt tgtcctaaac ttacaaacat tccactcatt ctgtttgtaa 750

 ctgtgattat aatttttgtg ataatttctg gcctgattga aggaaatttg 800

 agaggtctgc atttatatat tttaaataga tttgataggt ttttaaattg 850

 ctttttttca taaggtattt ataaagttat ttggggttgt ctgggattgt 900

 gtgaaagaaa attagaacca cgctgtattt acatttacct tggtagttta 950

 tttgtggatg gcagttttct gtagttttgg ggactgtggt agctcttgga 1000

 ttgttttgca aattacagct gaaatctgtg tcatggatta aactggctta 1050

 tgtggctaga ataggaagag agaaaaaatg aaatggttgt ttactaattt 1100

 tatactccca ttaaaaatct ctaatgttaa gaaaacctta aataaacatg 1150

 attgatcaat atggcagatg atttacagtc cattatatga catttgtaag 1200

 ccactcaaca ctagccttac aaggttcatg aaaggaggaa aacattaatt 1250

 ctttctgcct ttgctgatat aatccacata gtaataattt aagctataat 1300

 ttatttttaa aatgagtgcc tcttgggaag cttcttttct gttctaacag 1350

 ttccctgtta aaatgaaaat cttaggccag tgcagtggct cacacctgta 1400

 atctcagcac tttgggaggc tgaggtgggt ggatcacttg aggtcaggag 1450

 ttcgagacca gcctggccaa catggtgaaa ccctgtctct actaaaaata 1500

 cagaaaaatt agccagggtt ggtgcatgtg cctgtaatcc cagctactca 1550

 ggaggccaaa gcaggagaat tgcttgaacc cgggaggtgg aggttgcagt 1600

 gaaccaagat cgcaccactg cattccagcc taagcaatag agcgagactc 1650

 cctcccaaaa aaaaaaaaaa aaaaaaaaaa aaa 1683

<210> 6407
<211> 99
<212> PRT
<213> Homo sapien

<400> 6407
 Met Ala Glu Gly Gly Phe Asp Pro Cys Glu Cys Val Cys Ser His
   1               5                  10                  15

 Glu His Ala Met Arg Arg Leu Ile Asn Leu Leu Arg Gln Ser Gln
                  20                  25                  30

 Ser Tyr Cys Thr Asp Thr Glu Cys Leu Gln Glu Leu Pro Gly Pro
                  35                  40                  45

 Ser Gly Asp Asn Gly Ile Ser Val Thr Met Ile Leu Val Ala Trp
                  50                  55                  60

 Met Val Ile Ala Leu Ile Leu Phe Leu Leu Arg Pro Pro Asn Leu
                  65                  70                  75

 Arg Gly Ser Ser Leu Pro Gly Lys Pro Thr Ser Pro His Asn Gly
                  80                  85                  90

 Gln Asp Pro Pro Ala Pro Pro Val Asp
                  95

<210> 6408
<211> 1743
<212> DNA
<213> Homo sapien

<400> 6408
 ccacgcgtcc ggctacctgt gcatcgtgct gctcatgctg ctgctgctca 50

 tcttctggat cgcgccggcc catgggccca ccaacatcat ggtctacatc 100

 agcatctgct ccttgctggg cagtttcacc gtgccttcca ccaagggcat 150

 cgggctggcg gcccaagaca tcttgcataa caacccgtcc agtcagagag 200

 ccctctgcct gtgcctggta ctcctggccg tgctcggctg cagcatcatc 250

 gtccagttca ggtacatcaa caaggcgctg gagtgcttcg actcctcggt 300

 gttcggggcc atctactacg tcgtgtttac cacgctggtc ctgctggcct 350

 cagccatcct cttccgggag tggagcaacg tgggcctggt ggacttcttg 400

 gggatggcct gtggattcac gaccgtctcc gtggggattg tccttataca 450

 ggtgttcaaa gagttcaatt tcaaccttgg ggagatgaac aaatctaata 500

 tgaaaacaga ctagattgca ataggagctt ggatggttcg aggaataggc 550

 attggaggtg gtttctggcc gtgattggat gtgaagtaga agaggtcctc 600

 gatcatggtg ttagaattga ctggatagta acaggtggtc tggtggatag 650

 cggggagcat ggctcagcac cagagcagag gcccagcagc ctctgcagcc 700

 caaacgtccc aacggtgcct ggaccatctc ttctgatgag acgaatctca 750

 ttttcatttc cattaacctg gaagctttca tgaatatttc ttctttaaaa 800

 cattttaaca ttatttaaac agaaaaagat gggctctttc tgggtaggtg 850

 gtacatgata gcagagatat ttttacttag attactttgg gaatgagaga 900

 ttgtgtcttg aactctgcac tgtacaggat gtgtctgtag ttgtgttagt 950

 ttgcattaag catgtataca ttcaagtatg tcatccaaat aagaggcata 1000

 tcattgaatt gtttttaatc ctctgacaag ttgactcttc gacccccacc 1050

 cccacccaag acattttaat agtaaataga gagagagaga agagttaatg 1100

 aacatgaggt agtgttccac tggcaggatg acttttcaat agctcaaatc 1150

 aatttcagtg cctttatcac ttgaattatt aacttaattt gactcttaat 1200

 gtgtatatgt tcttagatta gaataatgca acttcgagta tgctttaata 1250

 tttcaatatt caagttacaa atgtataagg cagttagaaa taatacagtc 1300

 acatgtcact taatgatagg gaaacattct gagaaatgca ttgtaaggtg 1350

 actttattgc gtgaacatca tggagtgcac ttatacaaac ctagatggga 1400

 cacctatgac ccacccaggc cagatggtac agcctgttgc tcctgggcca 1450

 cacacctgta cagcatgtga ctgcactgaa taccgcaggc aattgtaaca 1500

 cagtggtgag tatttgtgtt tacaaacata ggaaaggtac agtaaaacta 1550

 tggtattaca atgttatggg accaccgtca tgtaagtggt atgtctttga 1600

 cagaaacatg gttacgtggt tcatgactgt atattcactg gaagatagtc 1650

 aagactaaag acacattaga gcaaattgac ccctttaaca tgtgattatt 1700

 gtccaattaa agacagttga tttaagtagc aaaaaaaaaa aaa 1743

<210> 6409
<211> 159
<212> PRT
<213> Homo sapien

<400> 6409
 Met Leu Leu Leu Leu Ile Phe Trp Ile Ala Pro Ala His Gly Pro
   1               5                  10                  15

 Thr Asn Ile Met Val Tyr Ile Ser Ile Cys Ser Leu Leu Gly Ser
                  20                  25                  30

 Phe Thr Val Pro Ser Thr Lys Gly Ile Gly Leu Ala Ala Gln Asp
                  35                  40                  45

 Ile Leu His Asn Asn Pro Ser Ser Gln Arg Ala Leu Cys Leu Cys
                  50                  55                  60

 Leu Val Leu Leu Ala Val Leu Gly Cys Ser Ile Ile Val Gln Phe
                  65                  70                  75

 Arg Tyr Ile Asn Lys Ala Leu Glu Cys Phe Asp Ser Ser Val Phe
                  80                  85                  90

 Gly Ala Ile Tyr Tyr Val Val Phe Thr Thr Leu Val Leu Leu Ala
                  95                 100                 105

 Ser Ala Ile Leu Phe Arg Glu Trp Ser Asn Val Gly Leu Val Asp
                 110                 115                 120

 Phe Leu Gly Met Ala Cys Gly Phe Thr Thr Val Ser Val Gly Ile
                 125                 130                 135

 Val Leu Ile Gln Val Phe Lys Glu Phe Asn Phe Asn Leu Gly Glu
                 140                 145                 150

 Met Asn Lys Ser Asn Met Lys Thr Asp
                 155

<210> 6410
<211> 3537
<212> DNA
<213> Homo sapien

<400> 6410
 cgttatttgc agtggctttg gggactcagc agtggcaagt ccctgtgcat 50

 aatgtgaacc tgcagacttc aagatggggc ccctcctgca cccactaaca 100

 tgtctgccct tttttgtttt tatcctggaa caagtggaga aatggcagag 150

 ctggctgact ctggggaccc ttcccttttt cccatggctt catttcttcc 200

 tcaccacaac taattcgggg agctgagaag tcacacaggg tattcctctc 250

 ccttctctga tgttattaat taatagacca gagaataagg ttgcagatat 300

 tacatttgtt gtgtttttgt gttttgtttt tttttttaag gaaaatccca 350

 aacaaagccc agcatgattt gagaaaagag gatgttttcc cagggaaaat 400

 aattttttta acctgcctga gaatgattta tttatttgtt ggaggccatt 450

 ggtcagacag cctggagctt gggctgtgga agatttcaaa agcatagggc 500

 tgtggtctct ggaaacctat tacagcctgc agctgtgagc tgagccagtg 550

 acgaggtccc tggaaactca ggaaggctga caggtgggcc ttggggtatt 600

 ggtttgtgga gaaggaagca ttctttaggc tgcggcactc cttatagttt 650

 cccacccacc gagtgacatt caggcagaaa ttgagctcag gagacagcca 700

 gccttcccac atcccacttc acttcccggt ccacacgtaa agcagtgtgt 750

 ctccaaggag gcagtgagca attcccaagg tccccgtgtt gtgagaagcg 800

 cgctgctttc tccctttgca gggaaaaaaa aaggctttcc tggtgagatc 850

 atgagtcctt ccggcttcat ttctcattgt gggtttaact tctaaaacgc 900

 aaatggagtt tagagaggat gagcagaacc acaggacctg cccccatctc 950

 tcactcactg caattgcttc tactctgggc acaagtaggg tgtctgaaga 1000

 ccatgtttcc ctctggttct ctagtttgca gataacacag aagacactgg 1050

 ctagaacctt aagctttctg ccaaaaagat gcagagagca gggcagtagc 1100

 tactggcagt ggggtgtgaa taaagagtcc tttcacaacc aagttcactg 1150

 aggatttgga gcaccagctt cccagcagta tcgaggggtg gagaggtgta 1200

 cattcaggtg gaggggtaca tctaggggtg gagaggtgta cattctagaa 1250

 acagctgtta acacactcca ctttaaagac agcaagctag acctgcagga 1300

 tcaaagccac acactgtggt aggggttaca aatgtttatg gggcccagaa 1350

 tactagcata gatgcgtgaa atggttggtg tgaggcaaaa gggcatggtg 1400

 ggggcaagga tggggactgt ggtcttactg gcatgcacgt gacctaccca 1450

 gaatgagcag ctgctactca gccccaacct gtcattgttt gtaaaaatgt 1500

 aagcacagtg tagtggaatc ttccaatttg gaagggaagc cggaaatcca 1550

 gatttaatgg aaaaaatctg atttttcaac gtcgggtttt ttgtttgttt 1600

 gtttttgttt tttttaacag atagtgggca aagaaaaatt ccactgttcc 1650

 acgtgtacac tgccagcaac ctctgctctc tggagaggtg gtttaaagtg 1700

 agattatgca ttgccctggt agaagaggaa aaaagccagc atcaggtcag 1750

 ggcaaaaata acagcccatg ttgaactcgg aatggggacc tcttgctaag 1800

 tcattccact cctcaagaga ccattccaca gaggggggat ggatcattca 1850

 gctctcctgg tcccaagatt gtgctgaagg gaagaaggaa tagaatctgg 1900

 agatctggac tgctgcccct tagatatgca gaggtccaca tctgcctggg 1950

 gctacagctt gtgggactcc atcaaaccag gccgaaatgg caaagacagt 2000

 ctaggaggag gaggaggtag ggtgtgaaac agccaggctc tctccaaatc 2050

 ccaagtgttg acacagccat cttgtcccat ccctggaagc ctctttggaa 2100

 accacataga gctgtgctgg ctcacgggat gtcctgtttg cttctgcctc 2150

 agttacctta ctttgcccat gggtctacca caggcgctac ctcattgtgt 2200

 ctgctgagaa gtttacctgg gaggggggaa caaagttgtc caaatctgct 2250

 tgagctgaat gtatgatcta tgcaaattct ctctctcctc tctctcttcc 2300

 tctctggctc tcttagaagt ttttttgttt tgttttgttt tgttttgtgt 2350

 ttaccttgca aacaagatac tgtataggac cctcttaaga tggaggaggg 2400

 ctttcttgcg ccacctgtgt ctacccctca cgttgtcttt ggctctggtc 2450

 ttaccaggcg tatgcaggga gaaagtgacc tctcttccct ctccacttgg 2500

 ctgggaatat tccaactgcc tctgcctaca gataccacca gaaagcgggt 2550

 tctgcacctt gtcatccccc tccctaacgt catctactcc atccctcatg 2600

 ttcctccaac ttgcttctcc catccctcct tcaaaaacaa aacaaaacaa 2650

 aacaaaagcc ttaggtttct cctttttgaa atgtggcctt aacattattt 2700

 ttgggaagct gaccatccat cctttccctc ccatctccac caacatcaga 2750

 gaagacagca tcgtgaagct tctgtggcag cctcctaagg aaggggctgc 2800

 caatctgtag ttggcagatg ctataggaat tgcttacaaa tgtcgtcttt 2850

 aagaaaaatg ttcttatatt tttcctatgg gcaaaatgaa ggcttgggtg 2900

 ctcatctaaa gctcagccaa ctcctgaagc actctctcag agcatactgc 2950

 tgctgtaatg ggctggctta attatcggca gagtgcttga aaaggctttg 3000

 cagacctccc ctgcccccaa gactgggtga ctttatatgt acttcattca 3050

 agggtaaatc aggagacgtt ctccatttat ctcttcgtcc ttcctgcctg 3100

 gaaagtgata gcactaaata ttcccagcag atgggtagtg ttctcaaagg 3150

 aatcaccctt tccctacctt cagactctat tctttaccct tccattgctc 3200

 cagtgctgat ggaggccaaa gacaacccca gggttttcat aggaaattca 3250

 ctggaattgt gcgcaattgt ctttgtagtc cttttgcctt tttttttttt 3300

 aaatattatg ttgtcaatag catttgtttg ggtatttgtt ttagaggcct 3350

 cactctaagt tattaccgtc cccttcattg ttttcaaaga catgtggtga 3400

 tatagttttt aaaaataact attttgttat agatcataat atgcataaaa 3450

 ctgtacagaa atattttgta atgtgttgat tttaaaaaaa gaatctgtaa 3500

 ataaagtttt aaaaaaagaa aaaaaaaaaa aaaaagg 3537

<210> 6411
<211> 183
<212> PRT
<213> Homo sapien

<400> 6411
 Met Tyr Asp Leu Cys Lys Phe Ser Leu Ser Ser Leu Ser Ser Ser
   1               5                  10                  15

 Leu Ala Leu Leu Glu Val Phe Leu Phe Cys Phe Val Leu Phe Cys
                  20                  25                  30

 Val Tyr Leu Ala Asn Lys Ile Leu Tyr Arg Thr Leu Leu Arg Trp
                  35                  40                  45

 Arg Arg Ala Phe Leu Arg His Leu Cys Leu Pro Leu Thr Leu Ser
                  50                  55                  60

 Leu Ala Leu Val Leu Pro Gly Val Cys Arg Glu Lys Val Thr Ser
                  65                  70                  75

 Leu Pro Ser Pro Leu Gly Trp Glu Tyr Ser Asn Cys Leu Cys Leu
                  80                  85                  90

 Gln Ile Pro Pro Glu Ser Gly Phe Cys Thr Leu Ser Ser Pro Ser
                  95                 100                 105

 Leu Thr Ser Ser Thr Pro Ser Leu Met Phe Leu Gln Leu Ala Ser
                 110                 115                 120

 Pro Ile Pro Pro Ser Lys Thr Lys Gln Asn Lys Thr Lys Ala Leu
                 125                 130                 135

 Gly Phe Ser Phe Leu Lys Cys Gly Leu Asn Ile Ile Phe Gly Lys
                 140                 145                 150

 Leu Thr Ile His Pro Phe Pro Pro Ile Ser Thr Asn Ile Arg Glu
                 155                 160                 165

 Asp Ser Ile Val Lys Leu Leu Trp Gln Pro Pro Lys Glu Gly Ala
                 170                 175                 180

 Ala Asn Leu


<210> 6412
<211> 581
<212> DNA
<213> Homo sapien

<400> 6412
 ccgagaggtg gttacattcg ttgaaggaca ccagctgcgg aatttgcggc 50

 tttggcagac ccagctgagt cactgtcact gcctaccaat ctcgaccgga 100

 cctcgaccgg ctcgtctgtg ctgccaatcg actcggcgtg gcgtcggtcg 150

 tggtagatag gcggtcatgc atacgaattt tcagctcttg ttctggtgac 200

 cttttgaata cgtcttgtct ataaaagaaa ttcatgcctt tgtaaaatac 250

 acagattgaa atcatggcag gtccagaaag tgatgcgcaa taccagttca 300

 ctggtattaa aaaatatttc aactcttata ctctcacagg tagaatgaac 350

 tgtgtactgg ccacatatgg aagcattgca ttgattgtct tatatttcaa 400

 gttaaggtcc aaaaaaactc cagctgtgaa agcaacataa atggatttta 450

 aactgtctac ggttcttaac ctcatctgtt aagttcccat gcctggagaa 500

 gctaatgcca actcatcatg tgataattca atttgtacaa taaattatga 550

 acccaaaaaa aaaaaaaaaa aaaaaaaaaa a 581

<210> 6413
<211> 58
<212> PRT
<213> Homo sapien

<400> 6413
 Met Ala Gly Pro Glu Ser Asp Ala Gln Tyr Gln Phe Thr Gly Ile
   1               5                  10                  15

 Lys Lys Tyr Phe Asn Ser Tyr Thr Leu Thr Gly Arg Met Asn Cys
                  20                  25                  30

 Val Leu Ala Thr Tyr Gly Ser Ile Ala Leu Ile Val Leu Tyr Phe
                  35                  40                  45

 Lys Leu Arg Ser Lys Lys Thr Pro Ala Val Lys Ala Thr
                  50                  55

<210> 6414
<211> 3200
<212> DNA
<213> Homo sapien

<400> 6414
 caggaagggc catgaagatt aataaagatt tggactcagg gcaaatattt 50

 acttagtagc aataactcaa agaattactg ttgaataaat aagccaatta 100

 agcagccaat cacgtactat gcggatgcac acaaatgaaa ccctcacttc 150

 aacctgaaga cattcgcaca tgagttacgt agagggacct gcaggaagcg 200

 gtagagaaaa cataaggctt atgcgtttaa tttccacacc aatttcagga 250

 tctttgtcac tgacagcagc actaagactt gttaacttta tatagttaag 300

 aagaacaagg ctgagcgcga tgactcacgc ctgtaagcct agaactttgg 350

 gaggccaaag caggcagact gcttgagccc aggagttcca gaccagcctg 400

 ggcaacatgg caacacccca tctctacaaa aaaatacaag aatcagctgg 450

 gcgtggtgat gtgttcctgt aatctcagct actcgggagg cagaggcagg 500

 aggattgctt gaacccggga ggcagaggtt gtagttagcc gagatctcgc 550

 cactgcactc cagtctggac gacagagtga gactcagtct caaataaata 600

 aataaataca taaatataag gaaaaaaata aagctgcttt ctcctcttcc 650

 tcctctttgg tctcatctgg ctctgctcca ggcatctgcc acaatgtggg 700

 tgcttacacc tgctgctttt gctgggaagt tcttgagtgt gttcaggcaa 750

 cctctgagct ctctgtggag gagcctggtc ccgctgttct gctggctgag 800

 ggcaaccttc tggctgctag ctaccaagag gagaaagcag cagctggtcc 850

 tgagagggcc agatgagacc aaagaggagg aagaggaccc tcctctgccc 900

 accaccccaa ccagcgtcaa ctatcacttc actcgccagt gcaactacaa 950

 atgcggcttc tgtttccaca cagccaaaac atcctttgtg ctgccccttg 1000

 aggaagcaaa gagaggattg cttttgctta aggaagctgg tatggagaag 1050

 atcaactttt caggtggaga gccatttctt caagaccggg gagaatacct 1100

 gggcaagttg gtgaggttct gcaaagtaga gttgcggctg cccagcgtga 1150

 gcatcgtgag caatggaagc ctgatccggg agaggtggtt ccagaattat 1200

 ggtgagtatt tggacattct cgctatctcc tgtgacagct ttgacgagga 1250

 agtcaatgtc cttattggcc gtggccaagg aaagaagaac catgtggaaa 1300

 accttcaaaa gctgaggagg tggtgtaggg attatagaat ccctttcaag 1350

 ataaattctg tcattaatcg tttcaacgtg gaagaggaca tgacggaaca 1400

 gatcaaagca ctaaaccctg tccgctggaa agtgttccag tgcctcttaa 1450

 ttgaaggtga gaattgtgga gaagatgctc taagagaagc agaaagattt 1500

 gttattggtg atgaagaatt tgaaagattc ttggagcgcc acaaagaagt 1550

 gtcctgcttg gtgcctgaat ctaaccagaa gatgaaagac tcctacctta 1600

 ttctggatga atatatgcgc tttctgaact gtagaaaggg acggaaggac 1650

 ccttccaagt ccatcctgga tgttggtgta gaagaagcta taaaattcag 1700

 tggatttgat gaaaagatgt ttctgaagcg aggaggaaaa tacatatgga 1750

 gtaaggctga tctgaagctg gattggtaga gcggaaagtg gaacgagact 1800

 tcaacacacc agtgggaaaa ctcctagagt aactgccatt gtctgcaata 1850

 ctatcccgtt ggtatttccc agtggctgaa aacctgattt tctgctgcac 1900

 gtggcatctg attacctgtg gtcactgaac acacgaataa cttggatagc 1950

 aaatcctgag acaatggaaa accattaact ttacttcatt ggcttataac 2000

 cttgttgtta ttgaaacagc acttctgttt ttgagtttgt tttagctaaa 2050

 aagaaggaat acacacagga ataatgaccc caaaaatgct tagataaggc 2100

 ccctatacac aggacctgac atttagctca atgatgcgtt tgtaagaaat 2150

 aagctctagt gatatctgtg ggggcaatat ttaatttgga tttgattttt 2200

 taaaacaatg tttactgcga tttctatatt tccattttga aactatttct 2250

 tgttccaggt ttgttcattt gacagagtca gtattttttg ccaaatatcc 2300

 agataaccag ttttcacatc tgagacatta caaagtatct gcctcaatta 2350

 tttctgctgg ttataatgct tttttttttt tttgctttta tgccattgca 2400

 gtcttgtact ttttactgtg atgtacagaa atagtcaaca gatgtttcca 2450

 agaacatatg atatgataat cctaccaatt ttcaagaagt ctctagaaag 2500

 agataacaca tggaaagacg gcgtggtgca gcccagccca cggtgcctgt 2550

 tccatgaatg ctggctacct atgtgtgtgg tacctgttgt gtccctttct 2600

 cttcaaagat ccctgagcaa aacaaagata cgctttccat ttgatgatgg 2650

 agttgacatg gaggcagtgc ttgcattgct ttgttcgcct atcatctggc 2700

 cacatgaggc tgtcaagcaa aagaatagga gtgtagttga gtagctggtt 2750

 ggccctacat ttctgagaag tgacgttaca ctgggttggc ataagatatc 2800

 ctaaaatcac gctggaacct tgggcaagga agaatgtgag caagagtaga 2850

 gagagtgcct ggatttcatg tcagtgaagc catgtcacca tatcatattt 2900

 ttgaatgaac tctgagtcag ttgaaatagg gtaccatcta ggtcagttta 2950

 agaagagtca gctcagagaa agcaagcata agggaaaatg tcacgtaaac 3000

 tagatcaggg aacaaaatcc tctccttgtg gaaatatccc atgcagtttg 3050

 ttgatacaac ttagtatctt attgcctaaa aaaaaatttc ttatcattgt 3100

 ttcaaaaaag caaaatcatg gaaaattttt gttgtccagg caaataaaag 3150

 gtcattttaa tttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaggcca 3200

<210> 6415
<211> 361
<212> PRT
<213> Homo sapien

<400> 6415
 Met Trp Val Leu Thr Pro Ala Ala Phe Ala Gly Lys Phe Leu Ser
   1               5                  10                  15

 Val Phe Arg Gln Pro Leu Ser Ser Leu Trp Arg Ser Leu Val Pro
                  20                  25                  30

 Leu Phe Cys Trp Leu Arg Ala Thr Phe Trp Leu Leu Ala Thr Lys
                  35                  40                  45

 Arg Arg Lys Gln Gln Leu Val Leu Arg Gly Pro Asp Glu Thr Lys
                  50                  55                  60

 Glu Glu Glu Glu Asp Pro Pro Leu Pro Thr Thr Pro Thr Ser Val
                  65                  70                  75

 Asn Tyr His Phe Thr Arg Gln Cys Asn Tyr Lys Cys Gly Phe Cys
                  80                  85                  90

 Phe His Thr Ala Lys Thr Ser Phe Val Leu Pro Leu Glu Glu Ala
                  95                 100                 105

 Lys Arg Gly Leu Leu Leu Leu Lys Glu Ala Gly Met Glu Lys Ile
                 110                 115                 120

 Asn Phe Ser Gly Gly Glu Pro Phe Leu Gln Asp Arg Gly Glu Tyr
                 125                 130                 135

 Leu Gly Lys Leu Val Arg Phe Cys Lys Val Glu Leu Arg Leu Pro
                 140                 145                 150

 Ser Val Ser Ile Val Ser Asn Gly Ser Leu Ile Arg Glu Arg Trp
                 155                 160                 165

 Phe Gln Asn Tyr Gly Glu Tyr Leu Asp Ile Leu Ala Ile Ser Cys
                 170                 175                 180

 Asp Ser Phe Asp Glu Glu Val Asn Val Leu Ile Gly Arg Gly Gln
                 185                 190                 195

 Gly Lys Lys Asn His Val Glu Asn Leu Gln Lys Leu Arg Arg Trp
                 200                 205                 210

 Cys Arg Asp Tyr Arg Ile Pro Phe Lys Ile Asn Ser Val Ile Asn
                 215                 220                 225

 Arg Phe Asn Val Glu Glu Asp Met Thr Glu Gln Ile Lys Ala Leu
                 230                 235                 240

 Asn Pro Val Arg Trp Lys Val Phe Gln Cys Leu Leu Ile Glu Gly
                 245                 250                 255

 Glu Asn Cys Gly Glu Asp Ala Leu Arg Glu Ala Glu Arg Phe Val
                 260                 265                 270

 Ile Gly Asp Glu Glu Phe Glu Arg Phe Leu Glu Arg His Lys Glu
                 275                 280                 285

 Val Ser Cys Leu Val Pro Glu Ser Asn Gln Lys Met Lys Asp Ser
                 290                 295                 300

 Tyr Leu Ile Leu Asp Glu Tyr Met Arg Phe Leu Asn Cys Arg Lys
                 305                 310                 315

 Gly Arg Lys Asp Pro Ser Lys Ser Ile Leu Asp Val Gly Val Glu
                 320                 325                 330

 Glu Ala Ile Lys Phe Ser Gly Phe Asp Glu Lys Met Phe Leu Lys
                 335                 340                 345

 Arg Gly Gly Lys Tyr Ile Trp Ser Lys Ala Asp Leu Lys Leu Asp
                 350                 355                 360

 Trp


<210> 6416
<211> 4254
<212> DNA
<213> Homo sapien

<400> 6416
 agctcgccca aagagataca acctaatccc caacctactt ttagtttttt 50

 ttgttttttt ttttatggtt aaaagtaact tttgtagttt aaaaaaatct 100

 ttcctctttc atataaataa gaagtggaaa ttgccttttt attgtgtaat 150

 gtagaaaacc ctcaagtgtt ttttccgagc ttgggaaaga ttttgtgtag 200

 gaaatgtgca tagagtttgt attttatttt tattagcagc tgaaatgcct 250

 ttggttttgg cttctctctc tccctctctc tctctgtctc tccttctctc 300

 tctcccccca ccacccaccc ccacacacgt catctgcatt gttattggag 350

 cctgtactta gagggattaa gcccacaccc tggcttccat tccatatcag 400

 gtacaggatt tgatgttatt aacatttgtc gtcatacctc ataagtcggt 450

 ccctgccttg tctgtctagg cccatttggg gctccctgtg agtgattccc 500

 ctctctctgc tatgctggag acggttccag cctggaaagc ggccaagttc 550

 atcttctcac tgtgagtgga agctggatcg ggcccccgta gtcctggcag 600

 ccctgttgtc tggagggttc ttgttgtccc tcccattagc cagggcggag 650

 actgtctgag ctgtgcagga ggagggttgc tagtaggttc tgcttctgct 700

 tctctctgct ccactgtctg cagcccagat cctgttgggc ctggctggtg 750

 tctggtaacc atgggcctcc actgacccat ccctctcttt taaactgtca 800

 ggtcattatc aggcataggc agcctatagg gcccaaagaa ggcaaaaaga 850

 taagatttac tcaagtagca tttgggcaat gaggaaggaa aggtttcaaa 900

 tttaggggca gaagtgagag aatgagccaa cccatgtacc tgctgcaact 950

 gaaccagact gggttttcaa ggctcccaga cgtagagtag gaaacgtgct 1000

 cttctaaatg aggagggaga agataaagga aacttctagc ccctgtcctt 1050

 agtgctttga ggattttatt ttctccctta ctacgcttgc ttgacgtcac 1100

 tctctctcga cctccaaaca gcaggactct ttctctggga aaccgtcctt 1150

 ccaaaacgga atctatgtag acaatgggac attaggcaga gagctcagat 1200

 ggccctttta agggggctcc aagaaccaac atcactgctc ttttagataa 1250

 acctctgccc tccactcctt gcttgagtgg gttaaaggaa ctaacagttg 1300

 tccctttagg aggacaaaat ggggtcaaga ggacacagaa gagttgtata 1350

 gcaccagatt ggttccaaat aattaatgga tgtgtgcaca ttttctgttc 1400

 agggattaag accagaatat cagtggattt gttttcccca ccaagtggcc 1450

 tcttagacta gtcattaact tatggttagc tctaaagatt tcaaatagtg 1500

 gcagacagtg tcttctgaat gtaagttttg agaaatacga gtctgtcaga 1550

 gcggccataa gccataaaga gtcaatctct tcattatatt tttcatcatg 1600

 taaacaagtt tcccatttcc ctttcttaga ttgcaccagt gaaggagatg 1650

 ttttgcaaag attcagagaa ctaatttttc actggataag acctgagtaa 1700

 cccagacccc ccaccgtggt tcttttcaca gccctcgact ttgcacttaa 1750

 aaagggatat tgtaaatgaa aggctgcagt gccagtttta agaaagaatt 1800

 tctgtgaagt gtgaggactc tggagtctag ctcacataaa gagagtgtta 1850

 tataaaaatc cgacagctga actaggttgc tcttttttgg cagggagtgg 1900

 ggatgagatt tgacaccaat atgggcaaaa ttagataacc ttttggttaa 1950

 tataaatgat tttgatttgg aggcctaatt tgtagattgt gaaagcagct 2000

 tttagtttaa cttattcaca gaccccttat aattaccatg tttttttttt 2050

 tcttcctaaa tctcttggtt cagcttgtga atcttacgtg cccgtaaagt 2100

 tgggatgttg aattggctct tctttgttct ggcagtgagt caagtgtcca 2150

 gcattttttc ataagtgttt tttaaaattg ttctccagca ttttatggct 2200

 cctccctccc atgtcctcag acccagcaaa agcgtagagg cagaattaga 2250

 ggcctctcca ggccagctcc tctgcccaca tgtcatacaa ggtgtgaatt 2300

 tgagcacagt ccagaaatgg agacatccca cccccagttg aataatggcc 2350

 cattcatgcc aaccttgcca acacggagag ggcagagatg cactagaaga 2400

 ccttcatcct ccccttcctc tgccccaagt cactacagtt ggttctattg 2450

 aagccagtct ttaagaaacc tgggttaaag acaccagcac ttctgcttgc 2500

 tgggctggct ggacctgtga agccatgggc aggtagtgcc ctcttgagag 2550

 tcattttatt tggccacctt caggtgagac tatccataga cacatgctag 2600

 gataggcccc gctgggaggg cagttacagg agagagtagg tggtggtgac 2650

 gtgagggctg tgaaggatcc agagacaaga cttagatgtt tcgttcattc 2700

 actcattcat tcagttactc ctaagacttt tcagtttcat aaggaagagt 2750

 gttgcctgag gccctaggga atattgggga atagaaggga ttgaggaaac 2800

 attaataata gttattcaaa agacccaaat gcttatactt ctctctccct 2850

 tcttctctct ctgacacaca cacacacaca cacacacaca cacgtgcaca 2900

 ttcctccctt acatgctcat ttgtgcctta aatgtgcctt ataggtaaat 2950

 ccaggatgac aggaatccct cgtcactggg agattttgta tatattcttt 3000

 tattattaga ttgagttggg tgtggggaaa aatttttttc tgaaggctca 3050

 aaagtggttt cctaaaagtg agccactatc agatttgcac atcaggagaa 3100

 aagaaatagg gttacgtcca ttaggaaaat cccagtttgc aggagtgcaa 3150

 tcacatcaaa aaaacaacca gccaggatta aaggtattat aaatcctcat 3200

 agcggaacat ttctcagggc aaaggaacct ggctcatttg aagattaatg 3250

 ttccatgcct ttgtggtcaa agggtcagca cttaacacag gaaaaaacta 3300

 ggtgttgttt tgttttgtta ttttggacaa cataaaattc aggaatgttt 3350

 tatttagcct tggtttctag aaggaaggga aataatattt cttgagcatt 3400

 tactagggtg ttgcgtgctg tgctaagtaa attttaagtc tttcagtttt 3450

 atagatacgg aaaacaaggg tgactcttta ccacaggatg aataaagaac 3500

 taagtaatat gggaaatgca gcaatttctg gactagctga gccgattcct 3550

 tcctgtgagc acactgtaag ctttcaagtt ctctgggcag gaattacagc 3600

 acctgtcccc tgcaatggcc ctgctgtgtg atgctcatcg cttcccttcg 3650

 tgctggagca gtcccccagg tgtccatctc ctatcttttt gttccaatct 3700

 tctgtgagtt ccagctagca ggctttacat ctggggaaag gaaaaccagg 3750

 ggttttagct ctgttctctg ctcccatcct tcgctcacca gctgagtgag 3800

 aacatgaact ttttgcacca tgtacccatg gcttacacta cttagaaaat 3850

 caccttttca gataaaacag tttatgagtt catagagaac accagcactc 3900

 tttgacaaaa ctgtgagtga ccctttttaa acaatgctga gcaggccctg 3950

 agctataatc aacggtgagc tttaatgtct atgctgacag ttaggttttg 4000

 ctctcttttg taacaggtta cgtagaccag cagtgtttaa atctaaatac 4050

 gttgtgagtc tgttatctgt cctatcgcgt tttttaaatg actttttatt 4100

 ctttatcata gctaagtaaa taccaaaaaa aaaaaaagct ttgtaggaca 4150

 cttgtactta gtttgggaaa aaaaaataaa ttgaaattgt tatgcttttg 4200

 tatttccatt tcttgcaaat aaatattttt tcttaaatag taaaaaaaaa 4250

 aaaa 4254

<210> 6417
<211> 50
<212> PRT
<213> Homo sapien

<400> 6417
 Ala Arg Pro Lys Arg Tyr Asn Leu Ile Pro Asn Leu Leu Leu Val
   1               5                  10                  15

 Phe Phe Val Phe Phe Phe Met Val Lys Ser Asn Phe Cys Ser Leu
                  20                  25                  30

 Lys Lys Ser Phe Leu Phe His Ile Asn Lys Lys Trp Lys Leu Pro
                  35                  40                  45

 Phe Tyr Cys Val Met
                  50

<210> 6418
<211> 1444
<212> DNA
<213> Homo sapien

<400> 6418
 gtttctctta tttatgcctt gaggactaat ttctggtttt ctagctgtta 50

 atgcactgtt gaccttcata atggtgcctt acgcaagcga tcccttctgt 100

 gggggtctca tacaggggtg tgggcgatgc atgctttatt aaggctcttg 150

 tttcacctgg cagtgtactg tatcaacgta taatacagaa aaaaaatctc 200

 tttaaggtcc tccttcacaa agacatagag tgaaactccc tttacatgtc 250

 agtatttgtt caacacttta ggcaacttga ctgtcagtgt taaaatggaa 300

 aacaggaaaa tggaaaaatc tgaccaattc tgccaccctg agactttcat 350

 atagaccttg cacaacaatt gtatagatca cacaccggct gtatttaata 400

 tgtaacattt tcacacatat taaagataca gaagtattaa aaaaccccca 450

 atgttaatgt atttgcttaa aaggcacaag tttcacatat ctgtctagct 500

 atctgttggt aatacagaaa gtatactact tttttaaaaa agtgggcaga 550

 attcttgtgt atgtatattt gtgtgtacag tatgtgtatg tgtgtatata 600

 tatatattat atatatagat aatatataaa tatttttttt aaggagaaac 650

 tagaacgttt agctagaaaa ttccacagcc tgtgaagaaa tatttcaaaa 700

 tggccataaa ggaggtaaaa atgaaaaacc ataacctaac ttttatagag 750

 gctttatctt taatttaacg atgtgcggag gactttcttg cttgaatctg 800

 ttccgggctg tctgctctgt ccatcaaatg ggcaggtctg gaatgaggca 850

 ccttcggccg ttcagaagtg gcctgaacag aatgctggaa cccaggctgg 900

 actcggacac actaaggttt tgattttgaa tttcagcctt attagaagat 950

 ctaacctaag agtaagctaa ccacagggat tcttttgtag aacacttttt 1000

 atgcagatga agctattttt tccagcaagt agattcttcc agtttttcca 1050

 aggagtaatt tccccgaatt ggcataccac ggcgtggaca gctgatattt 1100

 cacccagctg ctggcttgtg ggtgtggctc tttgctttat atatatatac 1150

 acacatgtga gtctggctgg gctggtattt tgtttgatct tcctggaaat 1200

 gagcagtgac taacgctcac ataactggtt tttttttctt atctgggctg 1250

 atgaatacat ttacctaaga aactcatttc gttttactta agaggggaag 1300

 tgcagttttc ttttggcagt tcagaatcca agcacttgat ttgctgggtt 1350

 tggaaaactc cttttttggc cttctatgtg cttagccata acaattccat 1400

 taagcaagaa ggtaagcaaa agacaaaaaa aaaaaaaaaa aaaa 1444

<210> 6419
<211> 7136
<212> DNA
<213> Homo sapien

<400> 6419
 gcttatattt tttccagctc ccaaattccc tttattccac tttagtccct 50

 tcattttcag agatgaggaa acagattgct ttgttcaaag acagctagaa 100

 ctagaacaca ggctaatact tgctagccat gtgatatact aatgtcagcc 150

 aaatacgggc atttacactt tcagatgttt gccatatctg tgcacttact 200

 aattctgttt aatacaattt aaattgactc ctttaaataa gcttatttta 250

 aaggaaattt tttgctacta taaatagaaa accattatat cctttaaata 300

 gtaactctaa ataggaattc aaaacaaagc aacgttatta aaatttaatt 350

 taaaattaat ttaaatttaa ttgttattaa atttttaatt attgctgttc 400

 ttcgtcagaa atgtgtcaaa gcattgtttt catgtttgat gtcagttcct 450

 taattgtcta aacagaaaaa gcacagctaa tgcctctagt taagcttctg 500

 tataactttt ttaaatgaaa tgcttcttag aggggaaatg agagggcatg 550

 aatacatgtt tatatactaa agtatgattt catgtatatc agaagatctt 600

 attatatgga accaaaatta ttctttggtt gatttaattg ttcttgaaac 650

 ttcagttttt accttgaagg ttttagttag cttagcataa gtttattttt 700

 ctaaataagg aatctgattg cctcacaact cagatgtatc acagttatgg 750

 tgaaatagca atatattggt ttctgtaacc ttttaaatac cgtaatgaat 800

 taaaatctct tcagcaaaag caaatatatc tagggtgacg agaggtgttt 850

 ttagtgtatt tgaatgatgg aaatgttttt cttaaaatat ttctgaagca 900

 ttttttaaaa taattttttg aatttattga tgatagtagt tgtgtgttag 950

 tgtgaatgac tggtctaaat gtgtatgtca cttccaaggg attagtaggg 1000

 gtcagaatga tttgttttat tcattgactt ttcctttgac gtgttcttat 1050

 tcattgggct acatacattc cctgttgcct tctcaccaaa agtgccacta 1100

 cacaggctgt atttcattgt actgtagaaa aagacaagta gacctttttc 1150

 attcatgaga ttcctatgaa atctgttggt ggaggtataa aatgaggaga 1200

 cttttatggg ctagctagta ggagttttgc tgtgaaacct ttgtaacagg 1250

 tctatcagga actagggaga gaaataaatg caggaaatac ttgatcccat 1300

 taaactgagg atgaaaaaga catgataata ttttggggat tatttattgt 1350

 gtgattttcc ggctgatcag aagtgttaat tttttgttat acttgtgtca 1400

 aatacatata tatatatata ttttgaaatg gagtcttgct ctgtcaccca 1450

 ggctggagtg cagtggtgcg atctgggttc actgcaacct ctgcctccag 1500

 gttcaagtga tcctcctgcc tcagcctccc gagtagctag gactacaggc 1550

 acgtgccacc acgccctgct aatttttgta ttcttagtgg agatggggtt 1600

 tcaccatgtt ggccaggctg gtcttgaact cctgacctca agtgatcttc 1650

 ccaccttggc ctttctgaac tatttccttt acacacattt agaactacat 1700

 ctaactgtat tatagttttc actttcacca tcagacaaaa ttcagaagat 1750

 tcaagagaag gaaagtcgat tgtatttact catatttttg ctaccgtgtt 1800

 tttacatctc atattttaag gctctcttaa ttatttattt tctgtttagt 1850

 taatttcctc tagccattct ttatttatag tgggtctgct ggtaacaaat 1900

 tctctcaatt tttcctcgtc tgagaatgtc ttgacttccc ttccattttt 1950

 gtcagcacct gaaaaatact atgccactat cttctgggtt ctgtggtttc 2000

 tgatgagaac tccactgtca gtctaattgt cgttataaat gcagtgttct 2050

 ctctctctct ctgcttccag gatatttttt cttttttttt tttttttttt 2100

 tcttgagacg gagtctcact ctgtcgccca ggctggagtg cagtggcgca 2150

 attttggctc actgcaagct ctgcctcccg ggttcaagcg attactccca 2200

 ctttagcctc ccaagtagct aggactacaa ggcacaccac catgcctggc 2250

 taatttttgt atttttagta gagacggggt ttcaccatgt tgcccaggct 2300

 ggtctcgaac tcctgacatc aagtgatctt cctgcctccg cttcccaaag 2350

 tgctggaatt acaggcgtga gccactgctc ccagcctctt tattttttca 2400

 gctttactct ttcttctgtc tttttgacat gtgtgtccag tgacacacgt 2450

 gttagatttt gctatagtct cacgcacggg tctataaggc tctgtttttt 2500

 gtttcatttt gtttttccta ttttctctct attcagatcg agtaatttcc 2550

 actgttcagt tttatcatag ctgcttttaa atctttgtca ggtaattctg 2600

 tcatctaagt tttggcacct attgattatc ttttgcattg tttttgtttt 2650

 tgtttctgtt tttgttttga gatggagtct tgctctgttg cccaggttgg 2700

 agtgcagtgg cactgatctc ggctcactgc aacctcctcc tcccgggttc 2750

 aagtggttct cctgcctcaa cctccttagt agctgggatt acaggcatgt 2800

 gccaccacgc ccggctaatt ttgtattttt agtagagacc aggtttatcc 2850

 atgttggtca ggctggtctc aaactcccaa cctcaagtga tccgcctgcc 2900

 tcgacctccc aaagtgctgg gattacaggc gtgaaccact gcacccagcc 2950

 tatcttttgc attgttttaa atcttgttct tgctaggatg aatgattttc 3000

 tgttaaaact agatattttc atattatgtt cctaggctct ggatattatc 3050

 taaaccttct gtttccactg gcttttattg acactgcttt ggcaaggtca 3100

 tagggggtgc ctcattactg ccaggtggac atagaagtca agggtcccta 3150

 ctcagcctct actgatgcct caggaagagg atccttcttg ttattgctgg 3200

 gtgggggtgg aagtctagct gacacctact gaggtaggtg ctggggcatg 3250

 cccggccatc agggtgaaag tcctggctcc ctagttggcc tacttttaca 3300

 ttgccctaat agggcattgg agctcctcac tatggtttat gagctggaag 3350

 tcaaggctcc tcacttagct ttcgttggtg tgggtggtgg tggggcaaaa 3400

 ctgttttctg ggtttggctg gagtggagca gttactgtca aaagttttct 3450

 gtcttgccag gctgtccctt tcttgtttct ttggctagag agagcaagct 3500

 tttgttgtgg ctctttttgt ctgtgccagt tggcatttcc aggttgctgc 3550

 cttctttagc tccaagtctg ggatatatta ggcaaaaaga aaacccagag 3600

 aatttacacc accgtgtcat tccatgggtc ctgaggtccc ttacttagtc 3650

 tgccttctct ccacttttca cagtcttctc atgttttgta tataatgtcc 3700

 agggtcttta gttatactta gcagaaataa aagggaaaag tatgtctgct 3750

 ctatgcttct gtaagtggaa gtcttcaaat ttgcattttt gattccttta 3800

 aacagttttg taaaatatat aatcattatt gggcaaaatg tcccataaaa 3850

 tgtatatacc ttgtgatggt ttgcataata ttgtgttcaa gaggactgct 3900

 gaaaaataac atctttattt aaactgaaac gaattgttca cattattaat 3950

 gaaaactttt cccctctagg aaataatgca aaaggtgtcc caaggctcct 4000

 gaccagtgaa caaagatttg agaaagacag ccaagctcat gttttctcct 4050

 gatcaagaaa atcatccatc taaagcacca gtaaaatatg gtgaactcat 4100

 tgtcttaggc tataatgggt ctctcccaaa tggcgataga ggaaggagga 4150

 aaagtaggtt tgctttgttt aaaagaccta aggcaaatgg ggtgaagccc 4200

 agcactgtgc atattgcttg tactcctcag gctgcaaagg caataagcaa 4250

 caaagaccag catagcatat catatacttt gtctcgggcc cagactgtgg 4300

 tggttgaata tactcatgac agcaacacag atatgtttca gattggccgg 4350

 tcgactgaaa gccccattga ttttgtagta actgacacgg ttcctggaag 4400

 tcaaagtaat tctgatacac agtcagtaca aagcactata tcaagatttg 4450

 cctgcagaat catatgtgaa cggaatcctc cctttacagc acggatttat 4500

 gctgcaggat ttgactcatc aaaaaacatc tttcttgggg agaaggctgc 4550

 caaatggaag acatcagatg gacagatgga tggcttgacc actaatggtg 4600

 ttcttgtgat gcatccacgc aatgggttca cagaagactc caagcctgga 4650

 atatggagag aaatatcggt gtgtggaaat gtatttagcc tacgtgaaac 4700

 cagatcggct cagcagagag gaaaaatggt ggaaattgaa accaatcagt 4750

 tacaagatgg ctcgttaatt gacctctgtg gtgcaacatt gttatggcgt 4800

 actgcagaag gcctttccca cactcctacc gtgaagcatt tagaagcttt 4850

 aagacaggaa atcaatgcag cacgacctca gtgccctgta gggttcaaca 4900

 cactagcatt tcctagtatg aagaggaaag acgttgtaga tgaaaaacaa 4950

 ccatgggtat atctaaactg cggccatgta catggctatc ataactgggg 5000

 aaacaaagaa gaacgtgatg gaaaagatcg tgaatgtcct atgtgtaggt 5050

 ctgttggtcc ctatgttcct ctgtggcttg gatgtgaagc tggattttat 5100

 gtggacgccg gccctccaac ccatgcgttt agcccgtgtg ggcatgtgtg 5150

 ttcagaaaag acaactgcct attggtccca gatcccactt cctcatggta 5200

 ctcatacttt tcatgcagcc tgtccctttt gtgcacatca gttggctggt 5250

 gaacaaggct acatcagact tatttttcaa ggacctctag actaacagac 5300

 cattgtcttg caggactaca ttataaattt ataagctaag tgagttgggt 5350

 tttcgaacct gttgtccacg tcacagtttt tctgctctgg tcatttgcat 5400

 taagatgaag aattttttaa aacatttata ataaatagta gcaatttctg 5450

 agcaaaaatc tgggaaactc aagcaaagga atttctgaaa gtatcagtct 5500

 tctgaattct gagttttgaa aatatatttt gaggagaaaa agacatagtc 5550

 taatttgatg ccttcctttt agtgtttttg aatcacctat cctcagtgct 5600

 gaaattgttt tgtataactg agggtactgt tggttcaaac tatgttagtt 5650

 tacagtttgt tgcaaacatt gtaaaataca gcgacatgta tattaacttt 5700

 tttctattta tctttattat agaaaatacc ttagaatgtt cttgatagag 5750

 tagcatggta acgatggtgt cacacccttg gtgtgaatgg tagcttagtg 5800

 agcaacctag ctcaaggatt tgcaaagtta ggaagaagga cgagagagcc 5850

 tctctcccca ccccaatcta aatatggaat ttggtaaatt agaatacttt 5900

 gtaatttgta agaccaaatt catactaatt acccgcgtga aaggtgtttg 5950

 tttttaacaa cattgaagat aatcaggaaa gattttttct taatgtttct 6000

 ctcgagcgta gtactataac aaaaacttaa tgctaagaaa cattttatat 6050

 gctcctttgg atatgcaatt taatctagat tatctatttt tctcccatga 6100

 taactaatct gtttttagta tcagcagcat ttggcaagtt tattttttgg 6150

 atataaactg tggttcatct gttcactgtt tctagaaaaa aatcattgcc 6200

 ataagaaaaa gtataaatta gcaagaaagg agagtgactt gatttgcttt 6250

 tggaaaaaga aatgcttaat taattattct gtatttggcc ttattcgggc 6300

 attaggaaat ctagagatct aaagggttga atgacaatag tgcccccgtt 6350

 tttagcagac cagccttaac tctgggtttg aatcctaagg agattgccac 6400

 agtgagactt aaggaaatgt ttggttggca gatgagcacc aatgactgca 6450

 gcgtggagtg acgcactgca tggtctgttt attctctaat tccaatatgt 6500

 cttttgcttc cagaagcaag aaaagtttct tctctcccct ccttcccacc 6550

 cttttttcaa aggcaccaca agtatagaca gttgcactac atcaaatctt 6600

 tttttgacac ttgtagaaac cagtacactt ttagattaga cagtatcttc 6650

 ttttaatatt ttgatttgtt ttcctttagt ttgaaaagtt gtataatact 6700

 taactgactg tagcaaagtt ttatatgtgg tagcatacct ttaatttatc 6750

 ctattacaaa actgttctga attttctttt ggtttttaaa aaacaaaact 6800

 tgttgcttag aagccatgaa ttattttatt ttacttcaac tgtcgaaact 6850

 tccttgtttt aaaaaatgat catttgggtt cactcaggaa atgcatgtca 6900

 ggaaacttgt attataagtt tattagttgt gatgtatcag taactgctgt 6950

 tacccctttt tcaaagaaat gtaattgatt ttgaagtttt ctagattgtc 7000

 acatgctttg tgactaatgc aagaaagcaa gtcctgtgtt gtatttgttc 7050

 tagtcatttt tattcaggct atatattgta gcttaatttt tatttgcaat 7100

 taatttattt aaactaagta aatacttttc aaaata 7136

<210> 6420
<211> 418
<212> PRT
<213> Homo sapien

<400> 6420
 Met Phe Ser Pro Asp Gln Glu Asn His Pro Ser Lys Ala Pro Val
   1               5                  10                  15

 Lys Tyr Gly Glu Leu Ile Val Leu Gly Tyr Asn Gly Ser Leu Pro
                  20                  25                  30

 Asn Gly Asp Arg Gly Arg Arg Lys Ser Arg Phe Ala Leu Phe Lys
                  35                  40                  45

 Arg Pro Lys Ala Asn Gly Val Lys Pro Ser Thr Val His Ile Ala
                  50                  55                  60

 Cys Thr Pro Gln Ala Ala Lys Ala Ile Ser Asn Lys Asp Gln His
                  65                  70                  75

 Ser Ile Ser Tyr Thr Leu Ser Arg Ala Gln Thr Val Val Val Glu
                  80                  85                  90

 Tyr Thr His Asp Ser Asn Thr Asp Met Phe Gln Ile Gly Arg Ser
                  95                 100                 105

 Thr Glu Ser Pro Ile Asp Phe Val Val Thr Asp Thr Val Pro Gly
                 110                 115                 120

 Ser Gln Ser Asn Ser Asp Thr Gln Ser Val Gln Ser Thr Ile Ser
                 125                 130                 135

 Arg Phe Ala Cys Arg Ile Ile Cys Glu Arg Asn Pro Pro Phe Thr
                 140                 145                 150

 Ala Arg Ile Tyr Ala Ala Gly Phe Asp Ser Ser Lys Asn Ile Phe
                 155                 160                 165

 Leu Gly Glu Lys Ala Ala Lys Trp Lys Thr Ser Asp Gly Gln Met
                 170                 175                 180

 Asp Gly Leu Thr Thr Asn Gly Val Leu Val Met His Pro Arg Asn
                 185                 190                 195

 Gly Phe Thr Glu Asp Ser Lys Pro Gly Ile Trp Arg Glu Ile Ser
                 200                 205                 210

 Val Cys Gly Asn Val Phe Ser Leu Arg Glu Thr Arg Ser Ala Gln
                 215                 220                 225

 Gln Arg Gly Lys Met Val Glu Ile Glu Thr Asn Gln Leu Gln Asp
                 230                 235                 240

 Gly Ser Leu Ile Asp Leu Cys Gly Ala Thr Leu Leu Trp Arg Thr
                 245                 250                 255

 Ala Glu Gly Leu Ser His Thr Pro Thr Val Lys His Leu Glu Ala
                 260                 265                 270

 Leu Arg Gln Glu Ile Asn Ala Ala Arg Pro Gln Cys Pro Val Gly
                 275                 280                 285

 Phe Asn Thr Leu Ala Phe Pro Ser Met Lys Arg Lys Asp Val Val
                 290                 295                 300

 Asp Glu Lys Gln Pro Trp Val Tyr Leu Asn Cys Gly His Val His
                 305                 310                 315

 Gly Tyr His Asn Trp Gly Asn Lys Glu Glu Arg Asp Gly Lys Asp
                 320                 325                 330

 Arg Glu Cys Pro Met Cys Arg Ser Val Gly Pro Tyr Val Pro Leu
                 335                 340                 345

 Trp Leu Gly Cys Glu Ala Gly Phe Tyr Val Asp Ala Gly Pro Pro
                 350                 355                 360

 Thr His Ala Phe Ser Pro Cys Gly His Val Cys Ser Glu Lys Thr
                 365                 370                 375

 Thr Ala Tyr Trp Ser Gln Ile Pro Leu Pro His Gly Thr His Thr
                 380                 385                 390

 Phe His Ala Ala Cys Pro Phe Cys Ala His Gln Leu Ala Gly Glu
                 395                 400                 405

 Gln Gly Tyr Ile Arg Leu Ile Phe Gln Gly Pro Leu Asp
                 410                 415

<210> 6421
<211> 2848
<212> DNA
<213> Homo sapien

<400> 6421
 aaacttcatt gagcacctgg gtcgttttcc tgctcatatc ctggactgtc 50

 tttcagggat ttactaccgg cttccgggac ttgagcaagt cttgaatacg 100

 caggatgttc aggatgttca gaacgttcag aacattttag aaatgctgtt 150

 gcgactcctg gacacttacc gggacaagat tcccgaggag gccttgtcac 200

 catcctacct gactgtgtgt ctgaaactgc atgaagccat ctgcagcagc 250

 acaaagctac ttaagtttta cgagctgcca gccttatctg ccgagattgt 300

 ctgcagaatg attagacttc tatctctggt ggattctgca ggacagagag 350

 atgaaactgg aaataattca gtccaaacag tcttccaagg gacccttgct 400

 gctacgaaaa ggtggctccg agaagttttt acaaagaaca tgctcacatc 450

 ttcaggtgcc tcattcacat acgtcaagga aattgaggtc tggaggcggc 500

 tggtggaaat ccaattcccc gcggagcatg gctggaagga gtcgttgctg 550

 ggagacatgg aatggaggct cacaaaggag gaacccctct cccagatcac 600

 tgcctactgc aatagttgct gggacaccaa aggcttagag gacagtgtgg 650

 ccaagacctt cgagaaatgc atcattgaag ccgtgagctc agcctgccag 700

 gtgaacaatc tctcctcctg ggaaacggat tcgggctcac agctgtgttc 750

 tgccatgacc cagctaaggg ctatgaagca cccgctgggt ctcagctcct 800

 ccgctaactc agagattggg aagtgggcac cctcctccct cgccaagggc 850

 aatggcgctg agatctagtt ctctccggat tcctcagtgt gctgcacagt 900

 ccctgctgct cgcaccatcc tgcatgtgtt ccatatggaa tcacggccgt 950

 gcgcgtgtgg cacaagtcac acgggcttgc aggccgttcc tcagatggcc 1000

 ctgtcgtcac tgtggctgct ggtttgattg attgttaaca cttgctcagt 1050

 aggtgtgcgg gaagagactc caaaggttga cagaacattt atggaagcaa 1100

 aatatgtgaa atggaaaatt gtatcaattt atttagctct tttcggcaaa 1150

 ggggaagaga ttgtgccccc ctgtctccca ggaacagtct cgcaggcaat 1200

 gccacatgag gaagctccct gctggccatg gctgccctgc tcacatttcc 1250

 taattggaca cttaacccct gtacaagcac agccttgcgg ccacagggga 1300

 agtccagaaa cattgaggtc attgaattcc ggggaccaag gggttctaat 1350

 tttttaagtg actgatacct ttgataaggt tttcctttcc ctttttcgtt 1400

 aactctttgt tgagatattg ttcgtatgcc atacggtaca tctgtcaaaa 1450

 gttccagttc agcaggtttt ggggtagtca cagatatgta cagtcatcac 1500

 cacagttaat gacagagcat tttcatcact tcaaagagaa acccggcccc 1550

 tttagccatc atcctcctcc cctctagtca cccactcccc tctgcaggca 1600

 taaacaattg ctgaacataa acaactgctt ctgtggcttt ctctgttctg 1650

 actgtcatat gaatggaatc atatcatatg tggccttttg ggtatggctt 1700

 atttcactga gcataatgtt tttttgttgt tggtggtggt ggttgtttgt 1750

 tgtttttggg accgagtttc actctttttg cccaggctgg agtgcagtgg 1800

 tgcgatcctg gcttaccgca accactgcct cccgggttca agtgattctc 1850

 ctgcctcagc ctcccaagtg ctggaattac agctactttt tgtttaaaga 1900

 gtcttttaat tgtttaaaga acaatgtgcc gccacactcg gttccttttg 1950

 tatttttaga agagacaggg tttctccatg ttggtcaggc tggtctcgaa 2000

 ctcccgacct caggtgatcc acccaccttg gcctcccgaa gtgccgagat 2050

 tgcaggtgtg agccaccgcg cccggccgag cataatgttt tgaaagaccg 2100

 ctcaggctgg acacggttgc tcacgcctgt agtcacggca ctttgggagc 2150

 ccaggagttc aagacaagcc tgggtaacag agtaagaccc tgtctctata 2200

 aaaactaaaa aataaacaaa aaaaattagc caggcatggc cgggcacacc 2250

 tgtggtccca gctacttggg aggctgaggt gggaggctcc cttgggccca 2300

 gaaggtcaag gcagcggtga gccatgatcg caccactgca cttcaacctg 2350

 ggggacagag caagaccctg tctcaaaaag caataacaac aaaagtccat 2400

 ccatattgta gcttgtgtcc gtttacgtta agtattcctt acccaaaatg 2450

 cttgagacca gaagtgtttt ggatttcaga tgttttcaaa ttttggaata 2500

 tttgcattta cataatgaga tgtcttccag atgggaccca gagtctaacc 2550

 acaaaattca cttgtttcat atacatctta tacacatagc ctgaaggtaa 2600

 ttttatacaa tatttttaac aattttgtgc atgagacaaa gtttgtatta 2650

 agtatttgta tgttgaattt ttcacttgtg gcatcattat actcaaaaag 2700

 tttggatttt gtagtatttt ggatttgggg attaggaatg ctcaacctat 2750

 atttcatttt tttccatggc caaatattcc ccgtttatcc atgtgtccat 2800

 tgacggccat ctatgttgct tcttcggcta ttataaatct gctgatac 2848

<210> 6422
<211> 241
<212> PRT
<213> Homo sapien

<400> 6422
 Met Leu Leu Arg Leu Leu Asp Thr Tyr Arg Asp Lys Ile Pro Glu
   1               5                  10                  15

 Glu Ala Leu Ser Pro Ser Tyr Leu Thr Val Cys Leu Lys Leu His
                  20                  25                  30

 Glu Ala Ile Cys Ser Ser Thr Lys Leu Leu Lys Phe Tyr Glu Leu
                  35                  40                  45

 Pro Ala Leu Ser Ala Glu Ile Val Cys Arg Met Ile Arg Leu Leu
                  50                  55                  60

 Ser Leu Val Asp Ser Ala Gly Gln Arg Asp Glu Thr Gly Asn Asn
                  65                  70                  75

 Ser Val Gln Thr Val Phe Gln Gly Thr Leu Ala Ala Thr Lys Arg
                  80                  85                  90

 Trp Leu Arg Glu Val Phe Thr Lys Asn Met Leu Thr Ser Ser Gly
                  95                 100                 105

 Ala Ser Phe Thr Tyr Val Lys Glu Ile Glu Val Trp Arg Arg Leu
                 110                 115                 120

 Val Glu Ile Gln Phe Pro Ala Glu His Gly Trp Lys Glu Ser Leu
                 125                 130                 135

 Leu Gly Asp Met Glu Trp Arg Leu Thr Lys Glu Glu Pro Leu Ser
                 140                 145                 150

 Gln Ile Thr Ala Tyr Cys Asn Ser Cys Trp Asp Thr Lys Gly Leu
                 155                 160                 165

 Glu Asp Ser Val Ala Lys Thr Phe Glu Lys Cys Ile Ile Glu Ala
                 170                 175                 180

 Val Ser Ser Ala Cys Gln Val Asn Asn Leu Ser Ser Trp Glu Thr
                 185                 190                 195

 Asp Ser Gly Ser Gln Leu Cys Ser Ala Met Thr Gln Leu Arg Ala
                 200                 205                 210

 Met Lys His Pro Leu Gly Leu Ser Ser Ser Ala Asn Ser Glu Ile
                 215                 220                 225

 Gly Lys Trp Ala Pro Ser Ser Leu Ala Lys Gly Asn Gly Ala Glu
                 230                 235                 240

 Ile


<210> 6423
<211> 3686
<212> DNA
<213> Homo sapien

<400> 6423
 ccgcgcgtcc cgcccctccc gtgcgccgct gacgcgccgt gctccggcgc 50

 aggcgcacag gggacggttg ctggcccagg tgagcgggcg cgctggtcca 100

 ggtgagcggg cgcgtccccg cgacggcgct gcctgcccga ggcggttcac 150

 gtaaagacag cgagatcctg agggccagcc gggaaggagg cgtggatatg 200

 gagctggctg ctgccaagtc cggggcccgc gccgctgcct agcgcgtcct 250

 ggggactctg tggggacgcg ccccgcgccg cggctcgggg acccgtagag 300

 cccggcgctg cgcgcatggc cctgctctcg cgccccgcgc tcaccctcct 350

 gctcctcctc atggccgctg ttgtcaggtg ccaggagcag gcccagacca 400

 ccgactggag agccaccctg aagaccatcc ggaacggcgt tcataagata 450

 gacacgtacc tgaacgccgc cttggacctc ctgggaggcg aggacggtct 500

 ctgccagtat aaatgcagtg acggatctaa gcctttccca cgttatggtt 550

 ataaaccctc cccaccgaat ggatgtggct ctccactgtt tggtgttcat 600

 cttaacattg gtatcccttc cctgacaaag tgttgcaacc aacacgacag 650

 gtgctatgaa acctgtggca aaagcaagaa tgactgtgat gaagaattcc 700

 agtattgcct ctccaagatc tgccgagatg tacagaaaac actaggacta 750

 actcagcatg ttcaggcatg tgaaacaaca gtggagctct tgtttgacag 800

 tgttatacat ttaggttgta aaccatatct ggacagccaa cgagccgcat 850

 gcaggtgtca ttatgaagaa aaaactgatc tttaaaggag atgccgacag 900

 ctagtgacag atgaagatgg aagaacataa cctttgacaa ataactaatg 950

 tttttacaac ataaaactgt cttatttttg tgaaaggatt attttgagac 1000

 cttaaaataa tttatatctt gatgttaaaa cctcaaagca aaaaaagtga 1050

 gggagatagt gaggggaggg cacgcttgtc ttctcaggta tcttccccag 1100

 cattgctccc ttacttagta tgccaaatgt cttgaccaat atcaaaaaca 1150

 agtgcttgtt tagcggagaa ttttgaaaag aggaatatat aactcaattt 1200

 tcacaaccac atttaccaaa aaaagagatc aaatataaaa ttcatcataa 1250

 tgtctgttca acattatctt atttggaaaa tggggaaatt atcacttaca 1300

 agtatttgtt tactatgaaa ttttaaatac acatttatgc ctagaaggaa 1350

 cggacttttt ttttctattt taattacaca taatatgtaa ttaaagtaca 1400

 acataatatg ttgtttctct gtagcccgtt gagcatatga gtaagtcaca 1450

 tttctattag gactacttac aaggacaagg tttccatttt tccagttgta 1500

 aaattggaac catcagctga taacctcgta gggagcaacc ccaggatagc 1550

 taagtgttat gtaatatgcc tagaaggtga tgtgaatgcg attcagaagc 1600

 atagccactc ccattttatg agctactcac atgacaaatg tcatcttttg 1650

 ctataacctt tgccaagtta gagaaaagat ggatttaatg agataaatga 1700

 aaagatattt aacctaatat atcaaggcac tatttgctgt tatgctttgt 1750

 tatttatttc ccagcacttg ttccttattg tagatttttt aaagactgta 1800

 accttttact aactgtggtc ttactaaaat ttgtgcttga tactgctttt 1850

 caaaaagcct ttaattagag ccaaaaggat ggaaaaggca agatataaat 1900

 gccttttata gatctcttat ttacattgaa aattattacc atatgtttag 1950

 agcaaatcca agaaaacttc aacagcttct gaagatgtct atgaatgttg 2000

 aaaacttttc aatctcttgg aatgctcagt tatgttccta gaccggtctt 2050

 tgctgactac tggttgttaa cctttcccta gcctgggacc tcaagccata 2100

 tatatccttt gggtgaccca tggccaaagt tattaagatg aactgacttt 2150

 caaagtcaga gaaggacagc atagggagag gcggttattt gtaagtcatt 2200

 acaggtagaa cagggcagaa ggaaaagtat gttctggaga aagggccatg 2250

 ttcctaactt tggagatatg tcattgccgg gaacctagta tcttccaact 2300

 tgaattggtg gcagctgttc cagtgagaca aggcacatgt atgccttgtg 2350

 gctaagtgag caaactgggt ttccacttaa atgtttggga ccctcaattg 2400

 attctttatt tcaaaccttt ataaaaggta cagttttgta agccattatt 2450

 aataattaat gcttatcggc tgagccaccg ttcccggcct attgtagatt 2500

 ttcttaacta cttgctaagg aaatcatatc cttttacatg aactacaggt 2550

 ttagaacttg gttttaagac aactgctatg gccagaaggt aaatgggaat 2600

 tgccttattg aaggtaacat tgattgccta ataagaaaat gaattgtttg 2650

 ccacagagtt gaatttaatt tgagttagat agttcagaat gtagcacttg 2700

 ccctataaat gaatcagatt tgttctattt atataatatt agaattaata 2750

 tattatcatg taagtgggaa ttttattttg ttaagtggac tctcaaattt 2800

 tagaacttgt gtgaaatatc tcccagaaaa cacaaaaggt ttcaaggtat 2850

 cacccaaagc tagggaatca acaaacgtac tttattaatg caagaccaca 2900

 atttaagccc caggcaggaa tccaacagta acatttttcc tttaggttaa 2950

 gcagtaattt ttttgaattg tcatttttaa tgggtctcac acatgcatat 3000

 tgctaatatc attcatgttt gaggttttca acaaagaacc aatttattaa 3050

 tataatgtac aaaaatagtt ggttcatttt ctgaattcag tctttgaaat 3100

 aaaactcctt gttttggccg tgtttctgaa tgtattggtg attcaccccc 3150

 aagctaattt tttaaagtca tttttgaagt tgggaagtct catgagagat 3200

 gttgaagtat gtatttaatc aagagtcatg atttcaaact agttttacat 3250

 attaagcagt tagtgttcta atttaatggg taaatgtgtg tttggataaa 3300

 tatctgaaaa ttttatcctt aagtatatat aattatttgc ctcttatatg 3350

 tcttaaagct atttaaacaa ggtgttaaat gagccaaaac aattaagtaa 3400

 ttagaacagt acatttttat cagtctgtca tatgcaatga atgtatgtaa 3450

 tactaaaaaa tcatgactac ttttatcaaa gaaaaaccac acattaatcc 3500

 tattaatcat gaaagcgtag cattgtaaat taaaggtttt ctttgaggct 3550

 cttgaaagtg atcccattgc tttcctgttt taaaaatatt ttatgctctt 3600

 tatttccact tctgtgaatg tgatatttct attttgtgat tatgttactg 3650

 aataaacaaa cttgctacat aaaattctta gcaatt 3686

<210> 6424
<211> 189
<212> PRT
<213> Homo sapien

<400> 6424
 Met Ala Leu Leu Ser Arg Pro Ala Leu Thr Leu Leu Leu Leu Leu
   1               5                  10                  15

 Met Ala Ala Val Val Arg Cys Gln Glu Gln Ala Gln Thr Thr Asp
                  20                  25                  30

 Trp Arg Ala Thr Leu Lys Thr Ile Arg Asn Gly Val His Lys Ile
                  35                  40                  45

 Asp Thr Tyr Leu Asn Ala Ala Leu Asp Leu Leu Gly Gly Glu Asp
                  50                  55                  60

 Gly Leu Cys Gln Tyr Lys Cys Ser Asp Gly Ser Lys Pro Phe Pro
                  65                  70                  75

 Arg Tyr Gly Tyr Lys Pro Ser Pro Pro Asn Gly Cys Gly Ser Pro
                  80                  85                  90

 Leu Phe Gly Val His Leu Asn Ile Gly Ile Pro Ser Leu Thr Lys
                  95                 100                 105

 Cys Cys Asn Gln His Asp Arg Cys Tyr Glu Thr Cys Gly Lys Ser
                 110                 115                 120

 Lys Asn Asp Cys Asp Glu Glu Phe Gln Tyr Cys Leu Ser Lys Ile
                 125                 130                 135

 Cys Arg Asp Val Gln Lys Thr Leu Gly Leu Thr Gln His Val Gln
                 140                 145                 150

 Ala Cys Glu Thr Thr Val Glu Leu Leu Phe Asp Ser Val Ile His
                 155                 160                 165

 Leu Gly Cys Lys Pro Tyr Leu Asp Ser Gln Arg Ala Ala Cys Arg
                 170                 175                 180

 Cys His Tyr Glu Glu Lys Thr Asp Leu
                 185

<210> 6425
<211> 2983
<212> DNA
<213> Homo sapien

<400> 6425
 tctaaggtag cgagggaggc gaagaccgcg cgcgcctcag acgccccggc 50

 cgacgaacgc gcttgctctg tctgcgggtt cctaaccttg aagctaggcc 100

 agtgaggggc gaacaagacc tggtctctac tctcggccag tatatatgtt 150

 ggcgggcgtc ggggggacgg ggtagggtaa gtgacagacg tcagaccagg 200

 cagccagatt aagtcaaacc ctgtcgtttc ttcctcaaga ggagctcggt 250

 tctgcctgcc ccatcagcct cactgtcact acctcagttt aggtctgttg 300

 tttgcaaact tagcaataga gttgaggaga gatgcttgct aaaatgcgga 350

 ttcctaggcg ccccgagata ggaactctgg agctatggag taggaccctt 400

 ttgatttttg ctgaagcctc cttattattc aagccattct gagctttttg 450

 aagattgagt aattcttgtg gggggcattg ttagcagcca tttggaaatg 500

 aacttcaggg agatgttgtt ggagccttcc agccagaaca gtgatattaa 550

 ggaactgaat actatatgtg acatactgca gttaacatat agcaataatg 600

 actctctttt cgccccctag gaatgggtga atttaaggtc catcgagtac 650

 gtttctttaa ttatgttcca tcaggaatcc gctgtgtggc ttacaataac 700

 cagtcaaaca gattggctgt ttcacgaaca gatggcactg tggaaattta 750

 taacttgtca gcaaactact ttcaggagaa atttttccca ggtcatgagt 800

 ctcgggctac agaagctttg tgctgggcag aaggacagcg actctttagt 850

 gctgggctca atggcgagat tatggagtat gatttacagg cgttaaacat 900

 caagtatgct atggatgcct ttggaggacc tatttggagc atggctgcca 950

 gccccagtgg ctctcaactt ttggttggtt gtgaagatgg atctgtgaaa 1000

 ctatttcaaa ttaccccaga caaaatccag tttgaaagaa attttgatcg 1050

 gcagaaaagt cgcatcctga gtctcagctg gcatccctct ggtacccaca 1100

 ttgcagctgg ttccatagac tacattagtg tgtttgatgt caaatcaggc 1150

 agcgctgttc ataagatgat tgtggacagg cagtatatgg gcgtgtctaa 1200

 gcggaagtgc atcgtgtggg gtgtcgcctt cttgtccgat ggcactatca 1250

 taagtgtgga ctctgctggg aaggtgcagt tctgggactc agccactggg 1300

 acgcttgtga agagccatct catcgctaat gctgacgtgc agtccattgc 1350

 tgtagctgac caagaagaca gtttcgtggt gggcacagcc gagggaacag 1400

 tcttccattt tcagctggtc cctgtgacat ctaacagcag tgagaagcag 1450

 tgggtgcgga caaaaccgtt ccagcatcac actcatgacg tgcgcactgt 1500

 ggcccacagc ccaacagcgc tgatatctgg aggcactgac acccacttag 1550

 tctttcgtcc tctcatggag aaggtggaag taaagaatta cgatgccgct 1600

 ctccgaaaaa tcacctttcc ccaccgatgt ctcatctcct gttctaaaaa 1650

 gaggcagctt ctcctcttcc agtttgctca tcacttagaa ctttggcgac 1700

 tgggatccac agttgcaaca ggcaagaatg gggatactct tccactctct 1750

 aaaaatgcag atcatttact gcacctaaag acaaagggtc ctgagaacat 1800

 tatctgtagc tgtatctccc catgtggaag ttggatagcc tattctacag 1850

 tttctcggtt ttttctctat cggctgaatt atgaacatga caacataagc 1900

 ctcaaaaggg tttccaaaat gccagcattc cttcgctctg cccttcagat 1950

 tttgttttct gaagattcaa caaagctctt tgtagcatca aatcaaggag 2000

 ctctgcatat tgttcagctg tcaggaggaa gcttcaagca cctgcatgct 2050

 ttccagcctc agtcaggaac agtggaggcc atgtgtcttt tggcagtcag 2100

 tccagatggg aattggctag ctgcatcagg taccagtgct ggagtccatg 2150

 tctacaacgt aaaacagcta aagcttcact gcacggtgcc tgcttacaat 2200

 ttcccagtga ctgctatggc tattgccccc aataccaaca accttgtcat 2250

 cgctcattcg gaccagcagg tatttgagta cagcatccca gacaaacagt 2300

 atacagattg gagccggact gtccagaagc agggctttca ccacctttgg 2350

 ctccaaaggg atactcctat cacacacatc agttttcatc ccaagagacc 2400

 gatgcacatc cttctccatg atgcctacat gttctgcatc attgacaagt 2450

 cattgcccct tccaaatgac aaaaccttac tctacaatcc atttcctccc 2500

 acgaatgaat cagatgtcat ccggaggcgc acagctcatg cttttaaaat 2550

 ttctaagata tataagcctc tactcttcat ggatcttttg gatgaaagaa 2600

 cactcgtggc agtagaacgg cctctggatg acatcattgc tcagctccca 2650

 ccacccatta aaaagaagaa atttggaacc taaaacaggg cactgtctgt 2700

 gtccttcctt gaactgtcta ccctgttgct tttcacaaat catggtaata 2750

 aaacaagtta ttcttgagga ctagtcatta taaatgtttt cttccaaaat 2800

 aatggacagt catttccctt cattgaatga aaatgaatgg aaattccaaa 2850

 tgaggtattt gtattgggga taatgtgctc agtagctaca aactcatcta 2900

 atgttgattg agtcctgctt attctgtagg ccgcaatctc agaagaaaag 2950

 atatttgtgt tctgttccct attacatgcc taa 2983

<210> 6426
<211> 686
<212> PRT
<213> Homo sapien

<400> 6426
 Met Gly Glu Phe Lys Val His Arg Val Arg Phe Phe Asn Tyr Val
   1               5                  10                  15

 Pro Ser Gly Ile Arg Cys Val Ala Tyr Asn Asn Gln Ser Asn Arg
                  20                  25                  30

 Leu Ala Val Ser Arg Thr Asp Gly Thr Val Glu Ile Tyr Asn Leu
                  35                  40                  45

 Ser Ala Asn Tyr Phe Gln Glu Lys Phe Phe Pro Gly His Glu Ser
                  50                  55                  60

 Arg Ala Thr Glu Ala Leu Cys Trp Ala Glu Gly Gln Arg Leu Phe
                  65                  70                  75

 Ser Ala Gly Leu Asn Gly Glu Ile Met Glu Tyr Asp Leu Gln Ala
                  80                  85                  90

 Leu Asn Ile Lys Tyr Ala Met Asp Ala Phe Gly Gly Pro Ile Trp
                  95                 100                 105

 Ser Met Ala Ala Ser Pro Ser Gly Ser Gln Leu Leu Val Gly Cys
                 110                 115                 120

 Glu Asp Gly Ser Val Lys Leu Phe Gln Ile Thr Pro Asp Lys Ile
                 125                 130                 135

 Gln Phe Glu Arg Asn Phe Asp Arg Gln Lys Ser Arg Ile Leu Ser
                 140                 145                 150

 Leu Ser Trp His Pro Ser Gly Thr His Ile Ala Ala Gly Ser Ile
                 155                 160                 165

 Asp Tyr Ile Ser Val Phe Asp Val Lys Ser Gly Ser Ala Val His
                 170                 175                 180

 Lys Met Ile Val Asp Arg Gln Tyr Met Gly Val Ser Lys Arg Lys
                 185                 190                 195

 Cys Ile Val Trp Gly Val Ala Phe Leu Ser Asp Gly Thr Ile Ile
                 200                 205                 210

 Ser Val Asp Ser Ala Gly Lys Val Gln Phe Trp Asp Ser Ala Thr
                 215                 220                 225

 Gly Thr Leu Val Lys Ser His Leu Ile Ala Asn Ala Asp Val Gln
                 230                 235                 240

 Ser Ile Ala Val Ala Asp Gln Glu Asp Ser Phe Val Val Gly Thr
                 245                 250                 255

 Ala Glu Gly Thr Val Phe His Phe Gln Leu Val Pro Val Thr Ser
                 260                 265                 270

 Asn Ser Ser Glu Lys Gln Trp Val Arg Thr Lys Pro Phe Gln His
                 275                 280                 285

 His Thr His Asp Val Arg Thr Val Ala His Ser Pro Thr Ala Leu
                 290                 295                 300

 Ile Ser Gly Gly Thr Asp Thr His Leu Val Phe Arg Pro Leu Met
                 305                 310                 315

 Glu Lys Val Glu Val Lys Asn Tyr Asp Ala Ala Leu Arg Lys Ile
                 320                 325                 330

 Thr Phe Pro His Arg Cys Leu Ile Ser Cys Ser Lys Lys Arg Gln
                 335                 340                 345

 Leu Leu Leu Phe Gln Phe Ala His His Leu Glu Leu Trp Arg Leu
                 350                 355                 360

 Gly Ser Thr Val Ala Thr Gly Lys Asn Gly Asp Thr Leu Pro Leu
                 365                 370                 375

 Ser Lys Asn Ala Asp His Leu Leu His Leu Lys Thr Lys Gly Pro
                 380                 385                 390

 Glu Asn Ile Ile Cys Ser Cys Ile Ser Pro Cys Gly Ser Trp Ile
                 395                 400                 405

 Ala Tyr Ser Thr Val Ser Arg Phe Phe Leu Tyr Arg Leu Asn Tyr
                 410                 415                 420

 Glu His Asp Asn Ile Ser Leu Lys Arg Val Ser Lys Met Pro Ala
                 425                 430                 435

 Phe Leu Arg Ser Ala Leu Gln Ile Leu Phe Ser Glu Asp Ser Thr
                 440                 445                 450

 Lys Leu Phe Val Ala Ser Asn Gln Gly Ala Leu His Ile Val Gln
                 455                 460                 465

 Leu Ser Gly Gly Ser Phe Lys His Leu His Ala Phe Gln Pro Gln
                 470                 475                 480

 Ser Gly Thr Val Glu Ala Met Cys Leu Leu Ala Val Ser Pro Asp
                 485                 490                 495

 Gly Asn Trp Leu Ala Ala Ser Gly Thr Ser Ala Gly Val His Val
                 500                 505                 510

 Tyr Asn Val Lys Gln Leu Lys Leu His Cys Thr Val Pro Ala Tyr
                 515                 520                 525

 Asn Phe Pro Val Thr Ala Met Ala Ile Ala Pro Asn Thr Asn Asn
                 530                 535                 540

 Leu Val Ile Ala His Ser Asp Gln Gln Val Phe Glu Tyr Ser Ile
                 545                 550                 555

 Pro Asp Lys Gln Tyr Thr Asp Trp Ser Arg Thr Val Gln Lys Gln
                 560                 565                 570

 Gly Phe His His Leu Trp Leu Gln Arg Asp Thr Pro Ile Thr His
                 575                 580                 585

 Ile Ser Phe His Pro Lys Arg Pro Met His Ile Leu Leu His Asp
                 590                 595                 600

 Ala Tyr Met Phe Cys Ile Ile Asp Lys Ser Leu Pro Leu Pro Asn
                 605                 610                 615

 Asp Lys Thr Leu Leu Tyr Asn Pro Phe Pro Pro Thr Asn Glu Ser
                 620                 625                 630

 Asp Val Ile Arg Arg Arg Thr Ala His Ala Phe Lys Ile Ser Lys
                 635                 640                 645

 Ile Tyr Lys Pro Leu Leu Phe Met Asp Leu Leu Asp Glu Arg Thr
                 650                 655                 660

 Leu Val Ala Val Glu Arg Pro Leu Asp Asp Ile Ile Ala Gln Leu
                 665                 670                 675

 Pro Pro Pro Ile Lys Lys Lys Lys Phe Gly Thr
                 680                 685

<210> 6427
<211> 3857
<212> DNA
<213> Homo sapien

<400> 6427
 cactggtctg ctactgttaa gttgtatgcc attttgttag gccttctcaa 50

 gtgggaatca ggaacgctgc tgtgctctag agatgttttg ttcttcctgt 100

 agggctgaag cagtgcctac tcgatagaat cagtcatcat gcaaataaaa 150

 gccacctgag tcaaaggcaa agccagagtg cagcttggag caaagaagtt 200

 aaaagcatat tggcagagga agagccctgg cattccagca ggagctaaca 250

 ggaaaaagaa aatcaatggc agtagccctg acacagccac ttctggtggt 300

 taccactcac ctggggattc agcaacaggt atctacgggg agggccgtgc 350

 atcctctact accctggagg atctggagag ccagtaccaa gaactagcag 400

 tggccctgga ttcaagctcc gcaataatca gtcaactcac tgaaaacatc 450

 aattcactgg ttcgcacatc taaggaggag aagaagcatg agatacatct 500

 ggtacagaag cttgggagga gcttgttcaa actcaaaaac cagacggaac 550

 aacgagaaca agagcacact gcagttggag cagcaagtaa aggagctgaa 600

 gaagtcaggt ggagctgaag agccaagagg ctccgagtct gcagcagcag 650

 ccagaccagt agctggagcc ccagtcccac aaggagcttg gatgtgcgga 700

 caagcagggt ggactcccca ggagcaccca ggcttgagtg gagaagctgt 750

 tggtacagga gaggcggcag gaggagcagg agaggctgca tgccattctt 800

 ttcgggctgc ggagaacagg gagctaaaca tcaccatcat ctaagagcgg 850

 gtcaaggaat tgaaaaaaaa aaacaaaaca tttaaggggt taatatccta 900

 cacaattcat ttacttcatt tgaatgttag agccacttat gtttatttgt 950

 gtttctaatt tatagtttaa atttatttgt gtttctaatt tatagtttaa 1000

 atttatttgt gtttctaatt tatagtttaa atttatttgt gtttctaatt 1050

 tataatttaa atttatttgt aaaaagttaa atgagagtgg gtgtttctct 1100

 catgttcact ctggcatctt ttagcatttt tttaatttga taattatagg 1150

 acgttagcat gcatatcgag tttgccctta tgtggtggga gttcaaacac 1200

 acaaagaccc actgtatgca cacaactgtt cttgctggtt tgggataggc 1250

 tgccatgctt ttttaatgtt agtacagcct gtatattcat tacggaattc 1300

 agataaaatt tccttatgtt ctgctgttat gtttgatcga atcctaatca 1350

 cagtgagctc ttcattagct caatatgcag tttgccctca agtgcgcggt 1400

 ctattacttt gtaatatgcc actgtgagta ctgacattta cagttgttta 1450

 aaggtggagc actggaaaca gcctttcccc ctttttctgt gtattgggga 1500

 tgggagtaat aacattttgg ggaggttttt aaatctccca gaagaggaaa 1550

 gtggcctgct ttggcaggtg tgtgcaggat agaatatgtt tcatttgttc 1600

 cggtgccaag aatgagcgct gtactacggt agttccctta ggatttgtat 1650

 gtgctctggg ctcatgaaga tactgcctca tgagctgtgg cagttgtact 1700

 cttttttgat gacctgaaaa gggattattt ctgaggaatg aaaggctccc 1750

 atcatgactg tggatgtgga aaaccttttc tagctgagag catttatatc 1800

 tacaatacat tttaaagtca gagttcatgt tccctgtttt aatcacatga 1850

 ctacatgtcc cagtacacaa aagggcactg gttggcgttc tccttaatgt 1900

 atttagtaaa gatcagaaga aatcctttaa gagtttaaat gccctggaac 1950

 agcatataca ggctctagtc aagaatgaat tcgagtgaag gaaagctgtg 2000

 tgacacctgg cattcctctg tgttcatgga gcttatttga ggctagaaga 2050

 tggattttac catctagacc tctctggcta atagctagtc ttcaaccatc 2100

 tgacatagga atttacttct tttccttgaa tggagaacac tttaaaaata 2150

 ataacaaaca ttattataaa ctaatatatg tgagagtact tagttgaaac 2200

 aaaaaggagt tttagtagac agtattatac tacatttgaa aatcaaggag 2250

 cagtttatgc aacgtaaaac gtttacaaac tgcagcacaa tctactgttc 2300

 gtgaatgtca aagtgtcatg aggaaagtgt ctatacaatc acagagttat 2350

 atttcctcac aaagttcttt acaaagagtg aaatatgttt ttatacctct 2400

 cagtttcagt tagaggcata ttttgtgtaa tatttatggc ttaaaatgga 2450

 ctaaaggtcc tgttcttgcc ttgtctgaac ttgccgcttt tgcattcttt 2500

 gagttcagtt taaagacagt tactttaagc ccattttaaa ccctcaggct 2550

 agaaatcgta ccactgttaa ttagccacat tatttggtct aacagtttat 2600

 cattctgaaa ctgagcttac ctaatacatt gataaattat ttcaaaggta 2650

 tttttatagt tcaaatcgct tcacttttac cctgacacgt ataaatgact 2700

 aggaatgacc ttcagatagc gtttagcaac tgtaaccaat ctgacaataa 2750

 tgtgttcatc aggtacctgt ggattaaatc acatactggc atatttaagc 2800

 tgaatgtcag tctgaaaaat aaatgtacta tattaactca aataccactc 2850

 tctgtgtagg tattttgtca tatgtttaag aaaaagctaa agagaatgga 2900

 aatcctatga caataactat gacaataact atgacaagtc tttcttcaaa 2950

 gtgcatgcag tcttttgcag tacctcattc agccaagtat ttgttctcta 3000

 cctcattcag tataaggcag cctttaattt gcttagaagg caacattaga 3050

 aggttagagt tcagcaggaa catagaattt taaaatgtga cttcaactga 3100

 ataaatttga atttctgtag ggagtaaaga atcaaaacac ctatttaaag 3150

 actgcaaaat atgataatta tttttaaagt aattgattaa acctggtagg 3200

 ttttcccaaa atgaaaaaca atcagttcta aaaccaaagc tgatttttag 3250

 aaaatgtgaa aatgtaaatc aaccctatcc ataatagatt ctctaaaact 3300

 ttatcttaca gtcactttca aataactatt caaaaatgta actgctatat 3350

 taacgtctta aaataattta aaacatttta aaatatgaat actgtagttt 3400

 aaaacaaaga atctagggga aggaaaagta gacaaagaaa tgccaattcc 3450

 agtccaaagc tgtatttgcc aagttttctt agaatgactt ttaccgattt 3500

 atgaattctt atacacagaa tgcataatgg aaatactgat ttttgtctaa 3550

 agtggcatta ttgactgctg ctgtgatgct actgtaatgt aatacattat 3600

 taaattgttt caaggtgctg ttttgcctaa aaattttgtg tgtcttgaaa 3650

 actatagtat tgggtattga gactctgcaa attctcggca tgcttggcat 3700

 gaaggtaatc ggtttttatt cttacaaaat tgtaactatg taagtgtgtt 3750

 tattaaaaga acacaaacta aaaaagttaa caggaattaa agttgtggga 3800

 tgaaaaagtt acaggataaa aaaatactgt ggaaaagtgg caaaaaaaaa 3850

 gttgtgg 3857

<210> 6428
<211> 118
<212> PRT
<213> Homo sapien

<400> 6428
 Met Arg Tyr Ile Trp Tyr Arg Ser Leu Gly Gly Ala Cys Ser Asn
   1               5                  10                  15

 Ser Lys Thr Arg Arg Asn Asn Glu Asn Lys Ser Thr Leu Gln Leu
                  20                  25                  30

 Glu Gln Gln Val Lys Glu Leu Lys Lys Ser Gly Gly Ala Glu Glu
                  35                  40                  45

 Pro Arg Gly Ser Glu Ser Ala Ala Ala Ala Arg Pro Val Ala Gly
                  50                  55                  60

 Ala Pro Val Pro Gln Gly Ala Trp Met Cys Gly Gln Ala Gly Trp
                  65                  70                  75

 Thr Pro Gln Glu His Pro Gly Leu Ser Gly Glu Ala Val Gly Thr
                  80                  85                  90

 Gly Glu Ala Ala Gly Gly Ala Gly Glu Ala Ala Cys His Ser Phe
                  95                 100                 105

 Arg Ala Ala Glu Asn Arg Glu Leu Asn Ile Thr Ile Ile
                 110                 115

<210> 6429
<211> 1482
<212> DNA
<213> Homo sapien

<400> 6429
 gaggcgccgg cggccacgcc gcggaaggcg cgggccgagc agagccgggc 50

 gttggagccc gcgcgcgcat ggaggcgttg ccggcagccc cctgagggca 100

 gcggggagac aagacccggc gacctcgcgc atccctcgag ccgccacgcg 150

 ctctcgccac cgggcggcga cgggccgcgg agccggcgcg gccatggcga 200

 cgggcggcca gcagaaggag aacacgctgc ttcacctctt cgccggcggg 250

 tgtggaggca cagttggtgc tattttcact tgtccactag aagtcattaa 300

 gacacggttg cagtcttcaa gattagctct ccggacagtc tactatcctc 350

 aggttcatct ggggaccatt agtggagctg gaatggtgag accaacatcc 400

 gtgacacctg gactctttca ggttctgaag tcgatcttgg agaaagaggg 450

 accaaagtca ctttttagag gcttgggtcc aaatttggtt ggagttgcac 500

 catcaagggc tgtatacttt gcatgttact ccaaagccaa agagcaattt 550

 aatggcattt tcgtgcctaa cagcaatatt gtgcatattt tctcagctgg 600

 ctctgcagct tttatcacaa attccttaat gaatcctata tggatggtta 650

 aaacccgaat gcagctagaa cagaaagtga ggggctctaa gcagatgaat 700

 acactccagt gtgctcgtta cgtttaccag accgaaggca ttcgtggctt 750

 ctatagagga ttaactgcct cgtatgctgg aatttccgaa actataatct 800

 gctttgctat ttatgaaagt ttaaagaagt atctgaaaga agctccatta 850

 gcctcttctg caaatgggac tgagaaaaat tccacaagtt tttttggact 900

 tatggcagct gctgctcttt ctaagggctg tgcctcctgc attgcttatc 950

 cacacgaagt cataaggacg aggctccggg aagagggcac caagtacaag 1000

 tcttttgtcc agacggcgcg cctggtgttc cgggaagaag gctaccttgc 1050

 cttttataga ggactgtttg cccagcttat ccggcagatc ccaaatactg 1100

 ccattgtgtt gtctacttat gagttaattg tgtacctgtt agaagaccgt 1150

 actcagtaac aggccggaaa attgtgctct agaagaataa aactgaaaaa 1200

 ctctagagaa ttttttttcc ccattgatgt ttagaaagtt tgagactgaa 1250

 acaggaaagg ccataaaata tctggttcat atcacctgtt ggacatttcc 1300

 ttttggattc atgctttctg gaaggtttaa attcattaac gttaatagtt 1350

 aattataact tttttttaac ttaagaggat tcagggttaa gcaccaacta 1400

 aattaaatca tgctatttaa tttaagtata aaaaaaaaaa aaaaaaaaaa 1450

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa cc 1482

<210> 6430
<211> 321
<212> PRT
<213> Homo sapien

<400> 6430
 Met Ala Thr Gly Gly Gln Gln Lys Glu Asn Thr Leu Leu His Leu
   1               5                  10                  15

 Phe Ala Gly Gly Cys Gly Gly Thr Val Gly Ala Ile Phe Thr Cys
                  20                  25                  30

 Pro Leu Glu Val Ile Lys Thr Arg Leu Gln Ser Ser Arg Leu Ala
                  35                  40                  45

 Leu Arg Thr Val Tyr Tyr Pro Gln Val His Leu Gly Thr Ile Ser
                  50                  55                  60

 Gly Ala Gly Met Val Arg Pro Thr Ser Val Thr Pro Gly Leu Phe
                  65                  70                  75

 Gln Val Leu Lys Ser Ile Leu Glu Lys Glu Gly Pro Lys Ser Leu
                  80                  85                  90

 Phe Arg Gly Leu Gly Pro Asn Leu Val Gly Val Ala Pro Ser Arg
                  95                 100                 105

 Ala Val Tyr Phe Ala Cys Tyr Ser Lys Ala Lys Glu Gln Phe Asn
                 110                 115                 120

 Gly Ile Phe Val Pro Asn Ser Asn Ile Val His Ile Phe Ser Ala
                 125                 130                 135

 Gly Ser Ala Ala Phe Ile Thr Asn Ser Leu Met Asn Pro Ile Trp
                 140                 145                 150

 Met Val Lys Thr Arg Met Gln Leu Glu Gln Lys Val Arg Gly Ser
                 155                 160                 165

 Lys Gln Met Asn Thr Leu Gln Cys Ala Arg Tyr Val Tyr Gln Thr
                 170                 175                 180

 Glu Gly Ile Arg Gly Phe Tyr Arg Gly Leu Thr Ala Ser Tyr Ala
                 185                 190                 195

 Gly Ile Ser Glu Thr Ile Ile Cys Phe Ala Ile Tyr Glu Ser Leu
                 200                 205                 210

 Lys Lys Tyr Leu Lys Glu Ala Pro Leu Ala Ser Ser Ala Asn Gly
                 215                 220                 225

 Thr Glu Lys Asn Ser Thr Ser Phe Phe Gly Leu Met Ala Ala Ala
                 230                 235                 240

 Ala Leu Ser Lys Gly Cys Ala Ser Cys Ile Ala Tyr Pro His Glu
                 245                 250                 255

 Val Ile Arg Thr Arg Leu Arg Glu Glu Gly Thr Lys Tyr Lys Ser
                 260                 265                 270

 Phe Val Gln Thr Ala Arg Leu Val Phe Arg Glu Glu Gly Tyr Leu
                 275                 280                 285

 Ala Phe Tyr Arg Gly Leu Phe Ala Gln Leu Ile Arg Gln Ile Pro
                 290                 295                 300

 Asn Thr Ala Ile Val Leu Ser Thr Tyr Glu Leu Ile Val Tyr Leu
                 305                 310                 315

 Leu Glu Asp Arg Thr Gln
                 320

<210> 6431
<211> 2587
<212> DNA
<213> Homo sapien

<400> 6431
 cccgagcccc gcccctccgg gcccgggtcg gcgcgcccag cctgccagcc 50

 gcgctgctgc tgctcctcct gctgtgggac cgctgaccgc gcggctgctc 100

 cgctctcccc gctccaagcg ccgatctggg cacccgccac cagcatggac 150

 gctcgccgcg tgccgcagaa agatctcaga gtaaagaaga acttaaagaa 200

 attcagatat gtgaagttga tttccatgga aacctcgtca tcctctgatg 250

 acagttgtga cagctttgct tctgataatt ttgcaaacac gaggctgcag 300

 tcagttcggg aaggctgtag gacccgcagc cagtgcaggc actctggacc 350

 tctcagggtg gcgatgaagt ttccagcgcg gagtaccagg ggagcaacca 400

 acaaaaaagc agagtcccgc cagccctcag agaattctgt gactgattcc 450

 aactccgatt cagaagatga aagtggaatg aattttttgg agaaaagggc 500

 tttaaatata aagcaaaaca aagcaatgct tgcaaaactc atgtctgaat 550

 tagaaagctt ccctggctcg ttccgtggaa gacatcccct cccaggctcc 600

 gactcacaat caaggagacc gcgaaggcgt acattcccgg gtgttgcttc 650

 caggagaaac cctgaacgga gagctcgtcc tcttaccagg tcaaggtccc 700

 ggatcctcgg gtcccttgac gctctaccca tggaggagga ggaggaagag 750

 gataagtaca tgttggtgag aaagaggaag accgtggatg gctacatgaa 800

 tgaagatgac ctgcccagaa gccgtcgctc cagatcatcc gtgacccttc 850

 cgcatataat tcgcccagtg gaagaaatta cagaggagga gttggagaac 900

 gtctgcagca attctcgaga gaagatatat aaccgttcac tgggctctac 950

 ttgtcatcaa tgccgtcaga agactattga taccaaaaca aactgcagaa 1000

 acccagactg ctggggcgtt cgaggccagt tctgtggccc ctgccttcga 1050

 aaccgttatg gtgaagaggt cagggatgct ctgctggatc cgaactggca 1100

 ttgcccgcct tgtcgaggaa tctgcaactg cagtttctgc cggcagcgag 1150

 atggacggtg tgcgactggg gtccttgtgt atttagccaa atatcatggc 1200

 tttgggaatg tgcatgccta cttgaaaagc ctgaaacagg aatttgaaat 1250

 gcaagcataa tatctggaaa atttgctgcc tgccttctac ttctcaaatc 1300

 tttcttgtaa aagtttccaa ttttttcact gaaacctgag ttaaaaatct 1350

 tgatgatcag cctgtttcat aagaaactcc aatcaagtta atcttagcag 1400

 acatgtgttt ctggagcatc acagaaggta tattgctagt tacactttgc 1450

 cctcctgcag tttcttctct gctcccaacc cccatctcat agcatccccc 1500

 tctatttcca atgctcctct ccaaccgctt agtttctgaa tttcttttaa 1550

 attacagttt tatgaaagca tattttattt acttggtgtt gaaatagccc 1600

 tcataaaacc taagcacttg gaaacacaat aatagtatta actaactaga 1650

 tctattgaat ttcagagaag agccttctaa cttgtttaca caaaaacgag 1700

 tatgatttag cattcatact agttgaaatt tttaatagaa tcaaggcaca 1750

 aaagtcttaa aaccatgtgg aaaaattagg taattattgc agattgatgt 1800

 ctctcaatcc catgtattgc gcttatgtta caagttgttg tcacagttga 1850

 gacttaattt ctcctaattt cttctgcccg aagggtaagt ggtgcgtcca 1900

 gcttacacaa tcataattca aaggttggtg ggcaatgtaa tacttaatta 1950

 aaataatgat ggaagagcta tctggagatt atgagtaagc tgatttgaat 2000

 tttcagtata aaactttagt ataattgtag tttgcaaagt ttatttcagt 2050

 tcacatgtaa ggtattgcaa ataaattctt ggacaatttt gtatggaaac 2100

 ttgatattaa aaactagtct gtggttcttt gcagtttctt gtaaatttat 2150

 aaaccaggca caaggttcaa gtttagattt taagcacttt tataacaatg 2200

 ataagtgcct ttttggagat gtaactttta gcagtttgtt aacctgacat 2250

 ctctgccagt ctagtttctg ggcaggtttc ctgtgtcagt attccccctc 2300

 ctctttgcat taatcaaggt atttggtaga ggtggaatct aagtgtttgt 2350

 atgtccaatt tacttgcata tgtaaaccat tgctgtgcca ttcaatgttt 2400

 gatgcataat tggaccttga atcgataagt gtaaatacag cttttgatct 2450

 gtaatgcttt tatacaaaag tttattttaa taataaaatg tttgttctaa 2500

 cttgtctgct tttttaaaaa taatcttact gtacttaatt ctaatttttt 2550

 cctcatattt aaataaaagg ccatttccac cttttct 2587

<210> 6432
<211> 371
<212> PRT
<213> Homo sapien

<400> 6432
 Met Asp Ala Arg Arg Val Pro Gln Lys Asp Leu Arg Val Lys Lys
   1               5                  10                  15

 Asn Leu Lys Lys Phe Arg Tyr Val Lys Leu Ile Ser Met Glu Thr
                  20                  25                  30

 Ser Ser Ser Ser Asp Asp Ser Cys Asp Ser Phe Ala Ser Asp Asn
                  35                  40                  45

 Phe Ala Asn Thr Arg Leu Gln Ser Val Arg Glu Gly Cys Arg Thr
                  50                  55                  60

 Arg Ser Gln Cys Arg His Ser Gly Pro Leu Arg Val Ala Met Lys
                  65                  70                  75

 Phe Pro Ala Arg Ser Thr Arg Gly Ala Thr Asn Lys Lys Ala Glu
                  80                  85                  90

 Ser Arg Gln Pro Ser Glu Asn Ser Val Thr Asp Ser Asn Ser Asp
                  95                 100                 105

 Ser Glu Asp Glu Ser Gly Met Asn Phe Leu Glu Lys Arg Ala Leu
                 110                 115                 120

 Asn Ile Lys Gln Asn Lys Ala Met Leu Ala Lys Leu Met Ser Glu
                 125                 130                 135

 Leu Glu Ser Phe Pro Gly Ser Phe Arg Gly Arg His Pro Leu Pro
                 140                 145                 150

 Gly Ser Asp Ser Gln Ser Arg Arg Pro Arg Arg Arg Thr Phe Pro
                 155                 160                 165

 Gly Val Ala Ser Arg Arg Asn Pro Glu Arg Arg Ala Arg Pro Leu
                 170                 175                 180

 Thr Arg Ser Arg Ser Arg Ile Leu Gly Ser Leu Asp Ala Leu Pro
                 185                 190                 195

 Met Glu Glu Glu Glu Glu Glu Asp Lys Tyr Met Leu Val Arg Lys
                 200                 205                 210

 Arg Lys Thr Val Asp Gly Tyr Met Asn Glu Asp Asp Leu Pro Arg
                 215                 220                 225

 Ser Arg Arg Ser Arg Ser Ser Val Thr Leu Pro His Ile Ile Arg
                 230                 235                 240

 Pro Val Glu Glu Ile Thr Glu Glu Glu Leu Glu Asn Val Cys Ser
                 245                 250                 255

 Asn Ser Arg Glu Lys Ile Tyr Asn Arg Ser Leu Gly Ser Thr Cys
                 260                 265                 270

 His Gln Cys Arg Gln Lys Thr Ile Asp Thr Lys Thr Asn Cys Arg
                 275                 280                 285

 Asn Pro Asp Cys Trp Gly Val Arg Gly Gln Phe Cys Gly Pro Cys
                 290                 295                 300

 Leu Arg Asn Arg Tyr Gly Glu Glu Val Arg Asp Ala Leu Leu Asp
                 305                 310                 315

 Pro Asn Trp His Cys Pro Pro Cys Arg Gly Ile Cys Asn Cys Ser
                 320                 325                 330

 Phe Cys Arg Gln Arg Asp Gly Arg Cys Ala Thr Gly Val Leu Val
                 335                 340                 345

 Tyr Leu Ala Lys Tyr His Gly Phe Gly Asn Val His Ala Tyr Leu
                 350                 355                 360

 Lys Ser Leu Lys Gln Glu Phe Glu Met Gln Ala
                 365                 370

<210> 6433
<211> 1631
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1482-1530
<223> Unknown base

<400> 6433
 cttctcatta gcattaacta ggttattgcc cagctttgga gagccttctt 50

 ttggcttatc atttattata agcccagaaa taggtgacta atcagagata 100

 aatgtatggg ttgtctgtat ctagttttat gccttttttt ttgcctaaga 150

 cgtagtcaaa ttaatatttt aactaataca tcttagcaga gtttagttaa 200

 gcacaaagtt aacagtgggt aggattgaat cttgaaagta atcatgtctg 250

 taatgttttt catgcatgca aaaagcacag acaaaaccac tcatgcccta 300

 ttaataaaca aaatacagat caaagttttc aaaagtaatc actctattta 350

 ttctaaatgt ctgtggcttt aggaaaatac caccagctag tacttaccta 400

 tttaaagatg tagaatttat tatcctctaa tattcttatc agttgtttcc 450

 acaactttag tttactattg gactttcaaa aatttaaaga attacaagta 500

 aaattcatta aacacttgtg tgtgaatagt aatacacagt aattagtaca 550

 gcatgttgct tcttcaacaa attgagtttt cagggaaatc agcaagtaaa 600

 tgaaatataa atttttggta aaagtatcaa acattcatct tgcccatttt 650

 tcctcttaaa ctttattatc taatcaaaca tagttttcca taagatgtaa 700

 taaaatatag ataaggttgg aatatttgag gatccatttg tggaactgaa 750

 tttaatgaga cttcattggt gatacactca atttttactg ggtaattagc 800

 taataatgtt ggtcactgtc tcacagttca agtagcttta agatgatgtg 850

 gcaaggaaaa cacaaagctt ttgggtaacc agcgttctta aatgtatggt 900

 ttttgaccag gtgaaccctt tagaagtgat ttctgtttta aaagtatgta 950

 cttaaaatac ctttggctgt gatgaatgta gatcccagca gaataccaaa 1000

 atcctatttt ttttgactga gtatttgtag atgcttaatg actgaaatga 1050

 atttggaggc actgatgaaa gtgatttttt taaagttctc aggtactgtt 1100

 caattattta atgttaagtt tagtatcaag atacagttgt ttttaaaatg 1150

 ccaaaatgct gtttattata cagaatattt tattacattt gcaatatctt 1200

 tgtatatagt gatttttttc ttgataataa atggaaaaat tctaaaacac 1250

 ttgctgaaat tttgttgcta tttaactttt aaaatatcag attttcttca 1300

 tatttatagc atcttcctaa caggaaaagg tagttttagt tgcttagaaa 1350

 cattagacat ttttatggaa tgctgttgct gaatatggtt gcatttgtaa 1400

 ctgtcctttg aaataatttt gtagagtact gaagtgcctt tttacaagat 1450

 ttttttcctt tttccttttc tggcttaacc annnnnnnnn nnnnnnnnnn 1500

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn gtactaggac ggtttctgct 1550

 gaggctctcc tcctggcttg cagagggctg ccttcccatc atcctcacat 1600

 ggtagagaga gagaaggatg gagatctagg g 1631

<210> 6434
<211> 114
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1482-1530
<223> Unknown amino acid

<400> 6434
 Met Thr Glu Met Asn Leu Glu Ala Leu Met Lys Val Ile Phe Leu
   1               5                  10                  15

 Lys Phe Ser Gly Thr Val Gln Leu Phe Asn Val Lys Phe Ser Ile
                  20                  25                  30

 Lys Ile Gln Leu Phe Leu Lys Cys Gln Asn Ala Val Tyr Tyr Thr
                  35                  40                  45

 Glu Tyr Phe Ile Thr Phe Ala Ile Ser Leu Tyr Ile Val Ile Phe
                  50                  55                  60

 Phe Leu Ile Ile Asn Gly Lys Ile Leu Lys His Leu Leu Lys Phe
                  65                  70                  75

 Cys Cys Tyr Leu Thr Phe Lys Ile Ser Asp Phe Leu His Ile Tyr
                  80                  85                  90

 Ser Ile Phe Leu Thr Gly Lys Gly Ser Phe Ser Cys Leu Glu Thr
                  95                 100                 105

 Leu Asp Ile Phe Met Glu Cys Cys Cys
                 110

<210> 6435
<211> 1993
<212> DNA
<213> Homo sapien

<400> 6435
 actcatttat accaggaaac agacaagaga acaagaggct gccgaagaca 50

 aaacttctct gcaagcacct gtgcacagca atgtgcgtgg gcatctgtga 100

 gaagaagaga atctgtgaag tttgagcaag cggccttccc aagatgtacc 150

 gaatatctca actgatgtca acaccagtag caagttcttc caggttggaa 200

 agagaatatg ctggagagct gtctcccacg tgcattttcc caagtttcac 250

 ctgtgattcc ctggatggtt accattcttt tgaatgcggc tccatagatc 300

 ccctgacagg ctcccactat acctgtcgcc gaagtcccag actcctcacc 350

 aatggctact atatttggac tgaagacagc ttcctgtgcg acaaagatgg 400

 caacataact ctgaacccat cccagaccag cgttatgtat aaggagaact 450

 tagttagtac ctccaaatct tggctgcatg gaagtatctt tggtgacatc 500

 aactcttctc caagtgaaga caactggttg aaggggacca ggaggttgga 550

 cacagaccat tgcaatggaa atgcagatga tttagactgt tcttctctga 600

 ctgatgactg ggagtcaggg aagatgaatg cagagtctgt gatcacctcc 650

 tcttccagcc acatcatatc tcagcctcct ggaggaaact cccatagctt 700

 gtctcttcag tcccagttga cagcttctga acgtttccaa gagaatagtt 750

 cggatcattc agaaaccagg ttgttgcaag aggtcttctt tcaggcaatc 800

 ctgcttgctg tgtgcttaat cacttctgca tgtgcaagat ggtttatggg 850

 agaaatatta gccagtgtct tcacatgctc attgatgata actgtagctt 900

 atgtgaaatc attgtttctc agccttgcca gctatttcaa aaccactgcc 950

 tgtgctcggt ttgtcaaaat ttgacaacca tttaggaatg ccttcgatga 1000

 atgtcctcca tctgaatatc tggaaattgt ccaacttgca gtctacttgg 1050

 aatcaagtgt tttattggaa gggagtaagc gagtaatgga gaaaaagcca 1100

 ttttagtttg actatgtgat tttaaaatga tctcagtttt tccatcaaaa 1150

 ttataatatg ctcatgaaaa taatattaat ttgccttccc tttgcaaaca 1200

 ccggcagttg aaaggaaaag gacggggaat gtgatggaaa agagaccgcc 1250

 tggaataaat gtccccctat gattctttaa ggcagtggtt ctcgagcttg 1300

 aattttcatt aggaaattct gtgaggagct tgtaaccaga tttctgggtc 1350

 tgccacatgc acctatctct tgctgaattg ctttaataga ataatgagag 1400

 caagtttgtc taactaatac caacctgaca acttgaataa caataaatgc 1450

 aatttgtaca taaaatataa tgctgcaaaa gtttgtcatt cacctcagtg 1500

 gagtgacttg atattaggtg gtaaccgtag atgatggtta atatgaaaat 1550

 ggacaggaaa gaagcatttt ctgaaagtta tattcttttg aaccacgttc 1600

 taaaccaagt ttttaatctt cttggggctc gtaattacct ttcactttaa 1650

 tgtcacttaa agatataaca cagaaaaatg ccttgagggc aaaatatagg 1700

 caaaacacca atgcgctttc aaatgcatga aaatggtgca gttgtaccct 1750

 tgagccttga ctcaagggct gtagatgttc cctttccacc ccccacactt 1800

 ggtgcgtgtt cacaaagcaa atatggcctg taattcaaat ttgttctatg 1850

 tgatactctc tgagtaaaaa ctcatacatg cagaaaattg tctttgctcg 1900

 aaatgataat gccaaaatat aactttatat ataatttgca tttagtacat 1950

 ttttggttaa aaaataaact aataaataag tgaagtcatc agc 1993

<210> 6436
<211> 276
<212> PRT
<213> Homo sapien

<400> 6436
 Met Tyr Arg Ile Ser Gln Leu Met Ser Thr Pro Val Ala Ser Ser
   1               5                  10                  15

 Ser Arg Leu Glu Arg Glu Tyr Ala Gly Glu Leu Ser Pro Thr Cys
                  20                  25                  30

 Ile Phe Pro Ser Phe Thr Cys Asp Ser Leu Asp Gly Tyr His Ser
                  35                  40                  45

 Phe Glu Cys Gly Ser Ile Asp Pro Leu Thr Gly Ser His Tyr Thr
                  50                  55                  60

 Cys Arg Arg Ser Pro Arg Leu Leu Thr Asn Gly Tyr Tyr Ile Trp
                  65                  70                  75

 Thr Glu Asp Ser Phe Leu Cys Asp Lys Asp Gly Asn Ile Thr Leu
                  80                  85                  90

 Asn Pro Ser Gln Thr Ser Val Met Tyr Lys Glu Asn Leu Val Ser
                  95                 100                 105

 Thr Ser Lys Ser Trp Leu His Gly Ser Ile Phe Gly Asp Ile Asn
                 110                 115                 120

 Ser Ser Pro Ser Glu Asp Asn Trp Leu Lys Gly Thr Arg Arg Leu
                 125                 130                 135

 Asp Thr Asp His Cys Asn Gly Asn Ala Asp Asp Leu Asp Cys Ser
                 140                 145                 150

 Ser Leu Thr Asp Asp Trp Glu Ser Gly Lys Met Asn Ala Glu Ser
                 155                 160                 165

 Val Ile Thr Ser Ser Ser Ser His Ile Ile Ser Gln Pro Pro Gly
                 170                 175                 180

 Gly Asn Ser His Ser Leu Ser Leu Gln Ser Gln Leu Thr Ala Ser
                 185                 190                 195

 Glu Arg Phe Gln Glu Asn Ser Ser Asp His Ser Glu Thr Arg Leu
                 200                 205                 210

 Leu Gln Glu Val Phe Phe Gln Ala Ile Leu Leu Ala Val Cys Leu
                 215                 220                 225

 Ile Thr Ser Ala Cys Ala Arg Trp Phe Met Gly Glu Ile Leu Ala
                 230                 235                 240

 Ser Val Phe Thr Cys Ser Leu Met Ile Thr Val Ala Tyr Val Lys
                 245                 250                 255

 Ser Leu Phe Leu Ser Leu Ala Ser Tyr Phe Lys Thr Thr Ala Cys
                 260                 265                 270

 Ala Arg Phe Val Lys Ile
                 275

<210> 6437
<211> 4579
<212> DNA
<213> Homo sapien

<400> 6437
 gctaagcgtc ccagccgcat ccctcccgca gcgacggcgg cccgggaccc 50

 gcgggctgtg aaccatgaac acccgcaata gagtggtgaa ctccgggctc 100

 ggcgcctccc ctgcctcccg cccgacccgg gatccccagg acccttctgg 150

 gcggcaaggg gagctgagcc ccgtggaaga ccagagagag ggtttggagg 200

 cagcccctaa gggcccttcg cgggagagcg tcgtgcacgc gggccagagg 250

 cgcacaagtg catacacctt gatagcacca aatataaacc ggagaaatga 300

 gatacaaaga agtatgtata gtcattcatt taacattcag aatgcttctc 350

 tctttttaca attggtttgt tttggtgtga agtattttta ttttctcatt 400

 tatatagact caccaaatct catcaaggtt ttttgttttt tttagttttg 450

 attatacctt taaaaatatt ctactattaa cacttctaag tttgtttctc 500

 tacgttagta acagaactca tgacatgatg gtagatcctg gatttctgtt 550

 ggcttgaaca actttacact tattgccaat aaacctcctt gagggtaggg 600

 accacatctt actcgttttt gtgctctctg tacttaatgc gtacataaca 650

 tgtttaattg atgtacagta aatataaatg ctgccattta aagttatagc 700

 attatccttt agaggtggaa gagaactaaa gttcatttag ttcacaaaga 750

 aattgtaggc ttgctcaagt ccagctgtgg ggctatgctg aaattcgatg 800

 gtctccttta ttacatgatt ggtaggaaat ttaacttcat gactaatgat 850

 ggacagaaag gcacaaaagg gaaaaagctc tctaaagagt ctccaccgga 900

 catgtagctc cgggtgggac agcgggtcag tgcagaatat gacaatcaca 950

 gccatgcagg gactatggga actgccagca gttctggtat cttacaagct 1000

 tttgatttaa atacttaata ggagattaag tctcaatgtg gtctggattt 1050

 cgaaatgttt cagaatttgt ttttctagta atggacattt gaaacaggtc 1100

 tcatgaggag ataaggggag gcgctggagt gacagaacta atttctctct 1150

 ggcgccccct gctgtcgtgc agagtgaaca tttaggaaat gagccctgct 1200

 ccccaggaag ccgactctgc acagtggtct ggagtgcctg aaaccagagc 1250

 aagggtctcc acctgtagca ccgagccctc attccctaga gtcgcagtaa 1300

 gcttgggagc attgaagata aagcgagtat gggcatcaga attctctggg 1350

 gatatgttta cctatgtgtg gaaagttctt attgacgtga aaatattcta 1400

 gttttgcaca cattttctat aggtaacttt aaaaattaac ttgatataga 1450

 gttttaaaaa tgccagaatg gtaggaaaat ctatacttct tttagtagga 1500

 gcccaggtgg tttttcaaat tcgaaccctc tgtgctgact cttggtgaga 1550

 atgtgccaca gggccgggcc caggatgacc tgtacgggtc agggctgaat 1600

 attgtgtttc taacctggaa gccttgttca ctcatgctca catatagtta 1650

 attgccttct aatagttgtt tcttatgctt tgaagggact ggttttcttt 1700

 tagaagtcta ataattgacg atttgatatt tctcgcctgg cttagttgcg 1750

 gagcaggagc tggccaacct ggagaagtgg aaggagcaga acagagctaa 1800

 accggttcac ctggtgccca gacggctagg tggaagccag tcagaaactg 1850

 aagtcagaca gaaacaacaa ctccagctga tgcaatctaa atacaagcaa 1900

 aagctaaaaa gagaagaatc tgtaagaatc aagaaggaag ctgaagaagc 1950

 tgaactccaa aaaatgaagg caattcagag agagaagagc aataaactgg 2000

 aggagaaaaa aagacttcaa gaaaacctta gaagagaagc atttagagag 2050

 catcagcaat acaaaaccgc tgagttcttg agcaaactga acacagaatc 2100

 gccagacaga agtgcctgtc aaagtgctgt ttgtggccca caatcctcaa 2150

 catggaaact tcctatcctg cctagggatc acagctgggc cagaagctgg 2200

 gcttacagag attctctaaa ggcagaagaa aacagaaaat tgcaaaagat 2250

 gaaggatgaa caacatcaaa agagtgaatt actggaactg aaacggcagc 2300

 agcaagagca agaaagagcc aaaatccacc agactgaaca caggagggta 2350

 aataatgctt ttctggaccg actccaaggc aaaagtcaac caggtggcct 2400

 cgagcaatct ggaggctgtt ggaatatgaa tagcggtaac agctggggta 2450

 tatgagaaaa tattgactcc tatctggcct tcatcaactg acctcgaaaa 2500

 gcctcatgag atgctttttc ttaatgtgat tttgttcagc ctcactgttt 2550

 ttaccttaat ttcaactgcc cacacacttg accgtgcagt caggagtgac 2600

 tggcttctcc ttgtcctcat ttatgcatgt ttggaggagc tgattcctga 2650

 actcatattt aaactctact gccagggaaa tgctacatta tttttctaat 2700

 tggaagtata attagagtga tgttggtagg gtagaaaaag agggagtcac 2750

 ttgatgcttt caggttaatc agagctatgg gtgctacagg cttgtctttc 2800

 taagtgacat attcttatct aattctcaga tcaggttttg aaagctttgg 2850

 gggtcttttt agattttaat ccctactttc tttatggtac aaatatgtac 2900

 aaaagaaaaa ggtcttatat tcttttacac aaatttataa ataaattttg 2950

 aactccttct gtataaatgg gtcattttta tttttaatga aaagttattg 3000

 gggttttctc tcttgaaggg tctcatttta attccctttt ccaggccgta 3050

 tagatcaaat atagtactgt cattactgtt ggctcttgtt ttggtcttga 3100

 cttactaata gtgttaccct gattttcaga gggggacagt ttatctccag 3150

 aaaggccaat gtttgtatac acatcagcta gacacaaata tagacatcat 3200

 atgtagtttg tacatgtttc agaaacttgt tttttctttg ctctgtgtaa 3250

 cctatttcct attgctagtt cagttggctt tcttattcac ttctgtgacc 3300

 ctgaaccagt tctcagaccc tagagtgtaa gagcattgat tttctacgct 3350

 gtgtaatcta gctcaatccc tctgtcccct ccgcctcacc gtcccccagc 3400

 caccacattg tatagcaaaa gcattacatt caatcctaga ataaaggtaa 3450

 atacaacaaa tcatctttgc agctggacaa ctaataatac tttgcagcat 3500

 taagagatct tctgtgttac cagtcactct gttgaaatga actttccgaa 3550

 tctctttatt caggaaaaca tggggttttg aaattcttgg gccaagagac 3600

 ataactgagg ggttcgcaga gctaggcaag ggtgcactag gaaagggcca 3650

 cattggtggg tggggggtaa cagagaacag atggtgtcag gaagtttctc 3700

 tggagtaaat aatgtggata ttcttggttt ccctctcctc cgccagctga 3750

 agctgtgtta gtgctgttga cactaatata aaatgtttgg tccatttgaa 3800

 atccttgtca ttgccttata tgggggaaac tcaatccccc agcctgtgtt 3850

 ggaaatatca ccaaactgat tgtaaatgtg cggctgtagc agacatttta 3900

 gtgtggtggt gtgcagccat ttcggcccta cacctgccag cctggctacc 3950

 ttacagttgt gttccgattt ttgcgtctat gcttggtgtg cctcacttgc 4000

 tgcattttcc agcatgcaac caggagttga cgtaggaaaa agggatgctt 4050

 tcttactttg gaagctctca gggaagttgg tgtcaatttc tcctccactg 4100

 cctggcctac cctgcactcc caaagatttt gtgcagatgg gtagttccat 4150

 tttttaaaaa ttgtgcagat atggaaaatt gtgacttact tcatgaccag 4200

 aactatctag aatatgtgtg ggggtataaa catcttgctt aaccaaatat 4250

 ctatgtaggc agaggtaacc aggagagaag caagacttgc tgcctaaagg 4300

 agcccaccat tttacttttc acatttaatc tgccacgttg aatcaattgg 4350

 aataaaacct gactcgcagg tgactggaca ggaaatccca aagttccacc 4400

 atttctatgc ttaattttaa cgtccccccg cttttttttt gtagaaaata 4450

 aaaacaagaa aatcgttcca atgtaagatg tttgttatag aaactttagg 4500

 caatacaggt gtgtaataaa atgtttaata aacttctaaa cacttttgta 4550

 tttggattta aaaaaaaaaa aaaaaaaaa 4579

<210> 6438
<211> 191
<212> PRT
<213> Homo sapien

<400> 6438
 Met Gln Ser Lys Tyr Lys Gln Lys Leu Lys Arg Glu Glu Ser Val
   1               5                  10                  15

 Arg Ile Lys Lys Glu Ala Glu Glu Ala Glu Leu Gln Lys Met Lys
                  20                  25                  30

 Ala Ile Gln Arg Glu Lys Ser Asn Lys Leu Glu Glu Lys Lys Arg
                  35                  40                  45

 Leu Gln Glu Asn Leu Arg Arg Glu Ala Phe Arg Glu His Gln Gln
                  50                  55                  60

 Tyr Lys Thr Ala Glu Phe Leu Ser Lys Leu Asn Thr Glu Ser Pro
                  65                  70                  75

 Asp Arg Ser Ala Cys Gln Ser Ala Val Cys Gly Pro Gln Ser Ser
                  80                  85                  90

 Thr Trp Lys Leu Pro Ile Leu Pro Arg Asp His Ser Trp Ala Arg
                  95                 100                 105

 Ser Trp Ala Tyr Arg Asp Ser Leu Lys Ala Glu Glu Asn Arg Lys
                 110                 115                 120

 Leu Gln Lys Met Lys Asp Glu Gln His Gln Lys Ser Glu Leu Leu
                 125                 130                 135

 Glu Leu Lys Arg Gln Gln Gln Glu Gln Glu Arg Ala Lys Ile His
                 140                 145                 150

 Gln Thr Glu His Arg Arg Val Asn Asn Ala Phe Leu Asp Arg Leu
                 155                 160                 165

 Gln Gly Lys Ser Gln Pro Gly Gly Leu Glu Gln Ser Gly Gly Cys
                 170                 175                 180

 Trp Asn Met Asn Ser Gly Asn Ser Trp Gly Ile
                 185                 190

<210> 6439
<211> 1267
<212> DNA
<213> Homo sapien

<400> 6439
 gcttcttgga gctgaatggt gtagcattac tatatggctt ttctctctag 50

 tcttcattgt gtcatctgta gtgagctata gagttttttt tgtttcggga 100

 atttttacaa cttgtttgca tgggttcacc tagtagcatt ggttcttgct 150

 tatagtcttt aatacacaat cagcaaagct tacaatccac tcaagagact 200

 tactattttg tcactgttga aaatgggcta aatgatgtaa attgaatgtg 250

 gctgtcaact aaaacaaaat tcagtataga attagtattc atccagtcat 300

 ggacatacct gtagcatagt tttctcttga gacataatag gccgtttcct 350

 actgtaaaaa cttacagcca gcttcataca ataaagtaaa ttttttcctg 400

 tgttttggca ggctcccgtc atacatgtgt attggtggtg ctgttaccaa 450

 aatgatcatt gttactatgg tggcatacag cttcatggag cagaaagttt 500

 ctacttggta tttaattaat aaaatgttga ggaatggctg aaacagttaa 550

 taatgaagta tttttacatt gctggtattg tgttttcagc atattggtag 600

 tttataatac agacttcttg ttgtcaaaga tcttcccgct taaaaattat 650

 attccttttc tcacgtgttt attagagaag aacaaatgat aaaaattagc 700

 attttaatga tatatttatg tgtagaaata gggggagaaa aaaaggccaa 750

 ctgaggtaat ctaggtgaaa aagtttgttt tcagtttagc tacatggttt 800

 aaccagaatt agaagaagaa cttcatttcc aaccaaagaa caggccgcac 850

 agccaccatt ttggggtctt gagcagagag agaaaacaaa taggtggttt 900

 gtgagaactc tgaattatgt agaaaaccag cttttctaca taataaataa 950

 gctttgcctt atttattaaa gttaggattt ctttgcagtt cttaaatgta 1000

 catttaaatt atatcaagtt gactttagaa gaaaaaaatt ataagcagcc 1050

 tacctctatc atgtatcttt gttgttaacc agagttttta aaatgaaaaa 1100

 aatttctgta atttattttt ggttctatga gattataatt aaaccccaaa 1150

 ttatatattt aaaaaacaaa aaccaaaaga tttttagtca ttattatagt 1200

 aactgaaatt aagtagagtt actttttttt aaaattattt ttaaaaataa 1250

 ttactacttt ggaaagt 1267

<210> 6440
<211> 1539
<212> DNA
<213> Homo sapien

<400> 6440
 ggacgcggtt tccgcggcaa cgcggctgga ccctggcctg cgctggctgg 50

 ggaggaagcg gttctagggg agcgtgcggg cgccggggtc cggcggcgag 100

 aggccacctt ctggccttgc gatgaatcct cggtttcccc ttctcagatg 150

 gggttttcgt gagggtacaa cgtcggcatt agacattcca ggtgacgccc 200

 gtacgcggtg ggcggttcgg gccggagctc tggaacgctg gccctggagg 250

 cgtcgacccc tcgttactga tgcagggacg cggtgcggac cagtcaggcc 300

 cagagctcgt ccttagatgt gggttcgaat ctctgccccg ccaacttgtg 350

 atcgtatcga ctcggcccag acgcaatttt cttctctgca aaatcgtcat 400

 aagaataatc acttgtcagg gtagctgcgg gcatcccatt cgttcctttc 450

 atcagcgccg ggcatatggg gcgtcagagg ctgagaacgt tgccgtgaag 500

 aggcttaaaa gcaagacccg gagtggcgac cttaaagagg acggactgaa 550

 gaaacgcggg aatgagctcc agacgcggga gtttcctctc tacaaagtta 600

 cactgcagca gcttgtctac cctgcccctt gtcttttgag aagttcaaac 650

 cttcagaaaa gttgcaagaa cacgaggcta aaggcagcag ttcactatac 700

 tgtgggttgt ctttgcgagg aagttgcatt ggacaaagag atgcagttca 750

 gcaaacagac cattgcggcc atttcggagc tgactttccg acagtgtgaa 800

 aattttgcca aagaccttga aatgtttgca agacatgcga aaagaaccac 850

 aattaacact gaagatgtga agctcttagc caggaggagt aattcactgc 900

 taaaatacat cacagacaaa agtgaagaga ttgctcagat taacctagaa 950

 cgaaaagcac agaagaaaaa gaagtcagag gatggaagca aaaattcaag 1000

 gcagccagca gaggctggag tggtggaaag tgagaattaa agtccctcgc 1050

 cgcttggaaa gtgcagcctt ctacaggtag agccacctag aaatgcatat 1100

 ggctgcaaag gaaactttga agggttaaat agagatttaa aaaaataaaa 1150

 taaaaaggct gggctagggt gctttttgtg ctgaattctc cacattgtta 1200

 actgccaaag ctagttttag agaatgagaa agtcttaagc aaaatactcc 1250

 caggtctcac tccagaacat aaaaatggtg tgtgatcgaa tggtatatat 1300

 tagaaattac atctgttgta attaaaattg tgtgagcaat taaacatggt 1350

 tgactttttc aagcaaaaat cagttcatct tttgatgtaa ttttctaggc 1400

 taaatggcaa tctctgaaag atgaataaag ctatatttat ttagcttttc 1450

 tggttactaa tgttgttttt aaacacatgc cgcctttggt caccaggtaa 1500

 aagggcatat gtttgggaat ggcccttttg acttttttt 1539

<210> 6441
<211> 256
<212> PRT
<213> Homo sapien

<400> 6441
 Met Gln Gly Arg Gly Ala Asp Gln Ser Gly Pro Glu Leu Val Leu
   1               5                  10                  15

 Arg Cys Gly Phe Glu Ser Leu Pro Arg Gln Leu Val Ile Val Ser
                  20                  25                  30

 Thr Arg Pro Arg Arg Asn Phe Leu Leu Cys Lys Ile Val Ile Arg
                  35                  40                  45

 Ile Ile Thr Cys Gln Gly Ser Cys Gly His Pro Ile Arg Ser Phe
                  50                  55                  60

 His Gln Arg Arg Ala Tyr Gly Ala Ser Glu Ala Glu Asn Val Ala
                  65                  70                  75

 Val Lys Arg Leu Lys Ser Lys Thr Arg Ser Gly Asp Leu Lys Glu
                  80                  85                  90

 Asp Gly Leu Lys Lys Arg Gly Asn Glu Leu Gln Thr Arg Glu Phe
                  95                 100                 105

 Pro Leu Tyr Lys Val Thr Leu Gln Gln Leu Val Tyr Pro Ala Pro
                 110                 115                 120

 Cys Leu Leu Arg Ser Ser Asn Leu Gln Lys Ser Cys Lys Asn Thr
                 125                 130                 135

 Arg Leu Lys Ala Ala Val His Tyr Thr Val Gly Cys Leu Cys Glu
                 140                 145                 150

 Glu Val Ala Leu Asp Lys Glu Met Gln Phe Ser Lys Gln Thr Ile
                 155                 160                 165

 Ala Ala Ile Ser Glu Leu Thr Phe Arg Gln Cys Glu Asn Phe Ala
                 170                 175                 180

 Lys Asp Leu Glu Met Phe Ala Arg His Ala Lys Arg Thr Thr Ile
                 185                 190                 195

 Asn Thr Glu Asp Val Lys Leu Leu Ala Arg Arg Ser Asn Ser Leu
                 200                 205                 210

 Leu Lys Tyr Ile Thr Asp Lys Ser Glu Glu Ile Ala Gln Ile Asn
                 215                 220                 225

 Leu Glu Arg Lys Ala Gln Lys Lys Lys Lys Ser Glu Asp Gly Ser
                 230                 235                 240

 Lys Asn Ser Arg Gln Pro Ala Glu Ala Gly Val Val Glu Ser Glu
                 245                 250                 255

 Asn


<210> 6442
<211> 3983
<212> DNA
<213> Homo sapien

<400> 6442
 gtgccaaggc ggctgggggc ggcgagcggg gccgcgggcg cgcaccgact 50

 caagagccga ctgtcagcct cggcgggccg gagttctccg gcgctgggac 100

 aggggcgctg ggacaggggc gctgggggcg agccctggcg ggggccaggt 150

 ccgaggaccc tgggcgcggc ggccccgcca ggaggtccgg ccgcgagcgt 200

 gacctcacgg ggaggggcca gcgcggcggc ctgggcgctg agccgagcgc 250

 cgggagagca gcgcagaagc cgagccgcga ggagcgcact ccgtggcccc 300

 gatggagcgg tacaaagccc tggaacagct gctgacagag ttggatgact 350

 tcctcaagat tcttgaccag gagaacctga gcagcacagc actggtgaag 400

 aagagctgcc tggcggagct cctccggctt tacaccaaaa gcagcagctc 450

 tgatgaggag tacatttata tgaacaaagt gaccatcaac aagcaacaga 500

 atgcagagtc tcaaggcaaa gcgcctgagg agcagggcct gctacccaat 550

 ggggagccca gccagcactc ctcggcccct cagaagagcc ttccagacct 600

 cccgccaccc aagatgattc cagaacggaa acagcttgcc atcccaaaga 650

 cggagtctcc agagggctac tatgaagagg ctgagccata tgacacatcc 700

 ctcaatgagg acggagaggc tgtgagcagc tcctacgagt cctacgatga 750

 agaggacggc agcaagggca agtcggcccc ttaccagtgg ccctcgccgg 800

 aggccggcat cgagctgatg cgtgacgccc gcatctgcgc cttcctgtgg 850

 cgcaagaagt ggctgggaca gtgggccaag cagctctgtg tcatcaagga 900

 caacaggctt ctgtgctaca aatcctccaa ggaccacagc cctcagctgg 950

 acgtgaacct actgggcagc agcgtcattc acaaggagaa gcaagtgcgg 1000

 aagaaggagc acaagctgaa gatcacaccg atgaatgccg atgtgattgt 1050

 gctgggcctg cagagcaagg accaggctga gcagtggctc agggtcatcc 1100

 aggaagtgag cggcctgcct tccgaaggag catctgaagg aaaccagtac 1150

 accccggatg cccagcgctt taactgccag aaaccagata tagctgagaa 1200

 gtacctgtcg gcttcagagt atgggagctc cgtggatggc caccctgagg 1250

 tcccagaaac caaagacgtc aagaagaaat gttctgctgg cctcaaactg 1300

 agcaacctaa tgaatctggg caggaagaaa tccacctcac tggagcctgt 1350

 ggagaggtcc ctcgagacat ccagttacct gaacgtgctg gtgaacagcc 1400

 agtggaagtc tcgctggtgc tctgtcaggg acaatcacct gcacttctac 1450

 caggaccgga accggagcaa ggtggcccag caacccctca gcctggtggg 1500

 ctgcgaggtg gtcccagacc ccagccccga ccacctctac tccttccgca 1550

 tcctccacaa gggcgaggag ctggccaagc ttgaggccaa gtcttccgag 1600

 gaaatgggcc actggctggg tctcctgctc tctgagtcag gctccaagac 1650

 agacccagaa gagttcacct acgactatgt ggatgccgat agggtctcct 1700

 gtattgtgag tgcggccaaa aactctctct tactgatgca gagaaagttc 1750

 tcagagccca acacttacat cgatggcctg cctagccagg accgccagga 1800

 ggagctgtat gacgacgtgg acctgtcaga gctcacagct gcggtggagc 1850

 ctaccgagga agccacccct gttgcagatg acccaaatga gagagaatct 1900

 gaccgggtgt acctggacct cacacctgtc aagtcctttc tgcatggccc 1950

 cagcagtgca caggcccagg cctcctcccc gacgttgtcc tgcctggaca 2000

 atgcaactga ggccctcccg gcagactcag gcccaggtcc caccccagat 2050

 gagccctgca taaagtgtcc agagaacctg ggagaacagc agctggagag 2100

 tttggagcca gaggatcctt ccctgagaat caccaccgtc aaaatccaga 2150

 cggaacagca gagaatctcc ttcccaccga gctgcccgga tgccgtggtg 2200

 gccaccccac ctggtgccag cccacctgtg aaggacaggt tgcgcgtgac 2250

 cagtgcagag atcaagcttg gcaagaatcg gacagaagct gaggtgaagc 2300

 ggtacacaga ggagaaggag aggcttgaaa agaagaagga agaaatccgg 2350

 gggcacctgg ctcagctccg gaaagagaaa cgggagctaa aggaaaccct 2400

 actgaaatgc acagacaagg aagtcctggc gagcctggag cagaagctga 2450

 aggaaattga cgaggagtgc cggggcgagg agagcaggcg cgtggacctg 2500

 gagctcagca tcatggaggt gaaggacaac ctgaagaagg ctgaggcagg 2550

 gcctgtgacg ttaggcacca ccgtggacac cacccacctg gagaatccca 2600

 aagctgtcac acctgcctct gccccagact gtaccccagt caactctgca 2650

 accacactca agaacaggcc tctctcggtc gtggtcacag gcaaaggcac 2700

 tgtactccag aaagccaagg aatgggagaa gaaaggagca agttagaaaa 2750

 caagcttcat ctaaagactc tcatgtcaat gtggaccttg gtgacaatcc 2800

 tgctttgtta aagcaaaaac tatgcgaaag ggtgagtctg tttagaagaa 2850

 aaagcaaaga ctgaggtact gtgaatggag agcttcagct aagaggaggc 2900

 tctgtccctt ttcagagcca aaggaaataa tacaacaaaa aggaggcttc 2950

 tttggagacc taagtctatt ggatgtaaac aagacgttgt atttagggat 3000

 gttctgtgtt tctttctttt ttgaagttgt catcaattgc tttactaaga 3050

 tttttaaata gtgaaaacct cctgtttaga ctttggtgga agatgaatca 3100

 aggaagcagg gccctgtctt atgggtcaca tgtctttggt gagtgagaag 3150

 acctaaactc ctggccatca tctcttatcc aatacttagc agttggggat 3200

 taaaccatcc ttgccttcag ttctctccaa tattaccagg cccaactcag 3250

 tcttcagtga ttttaaacag cattgacatc atctgtaaaa ccatcatctg 3300

 taaaaccatc tatgacatga gttttgagaa acaataatgg ggaaaatatt 3350

 tgggaccaag ctgaagcact aatcccacta agttaaagac ttctttccag 3400

 tccaaggcag gcctgaatca actgtcttta aataaaattt taagtgatgc 3450

 tgtattatat ataggaaaaa atgcttaaaa tcctgtcatt tagaacagtg 3500

 aaaagtatct tttgagatta aagtgactct ttactgtagg aaaaatatta 3550

 ctctgtgttt acagattcat tgctgtggtc aggccatttt taagggaaga 3600

 gttatttaat ataaatagtc tctgatttta agttctgttt aatgttcatt 3650

 ctccttccaa gaacaaagtg gtgatttttg gttagggtga tcgccctctt 3700

 aaaattggca gtgctgttcc ttgtgctgcc cctgtctttt cctctgatgg 3750

 catttttttt tttttttttt tttaacacag gttgaaacat ttcatctatt 3800

 atctctgcct catttctgga gggttgtgta tcagttctct aacacttgtt 3850

 cctgagaact aaatgtcttt tttattctta tttcctctct cataaacatt 3900

 tggtgacctt ttaccaagtg gtgagttagg ttttttaaaa taaaatgttc 3950

 attgtatttg aaaaaaaaaa aaaaaaaaaa aaa 3983

<210> 6443
<211> 814
<212> PRT
<213> Homo sapien

<400> 6443
 Met Glu Arg Tyr Lys Ala Leu Glu Gln Leu Leu Thr Glu Leu Asp
   1               5                  10                  15

 Asp Phe Leu Lys Ile Leu Asp Gln Glu Asn Leu Ser Ser Thr Ala
                  20                  25                  30

 Leu Val Lys Lys Ser Cys Leu Ala Glu Leu Leu Arg Leu Tyr Thr
                  35                  40                  45

 Lys Ser Ser Ser Ser Asp Glu Glu Tyr Ile Tyr Met Asn Lys Val
                  50                  55                  60

 Thr Ile Asn Lys Gln Gln Asn Ala Glu Ser Gln Gly Lys Ala Pro
                  65                  70                  75

 Glu Glu Gln Gly Leu Leu Pro Asn Gly Glu Pro Ser Gln His Ser
                  80                  85                  90

 Ser Ala Pro Gln Lys Ser Leu Pro Asp Leu Pro Pro Pro Lys Met
                  95                 100                 105

 Ile Pro Glu Arg Lys Gln Leu Ala Ile Pro Lys Thr Glu Ser Pro
                 110                 115                 120

 Glu Gly Tyr Tyr Glu Glu Ala Glu Pro Tyr Asp Thr Ser Leu Asn
                 125                 130                 135

 Glu Asp Gly Glu Ala Val Ser Ser Ser Tyr Glu Ser Tyr Asp Glu
                 140                 145                 150

 Glu Asp Gly Ser Lys Gly Lys Ser Ala Pro Tyr Gln Trp Pro Ser
                 155                 160                 165

 Pro Glu Ala Gly Ile Glu Leu Met Arg Asp Ala Arg Ile Cys Ala
                 170                 175                 180

 Phe Leu Trp Arg Lys Lys Trp Leu Gly Gln Trp Ala Lys Gln Leu
                 185                 190                 195

 Cys Val Ile Lys Asp Asn Arg Leu Leu Cys Tyr Lys Ser Ser Lys
                 200                 205                 210

 Asp His Ser Pro Gln Leu Asp Val Asn Leu Leu Gly Ser Ser Val
                 215                 220                 225

 Ile His Lys Glu Lys Gln Val Arg Lys Lys Glu His Lys Leu Lys
                 230                 235                 240

 Ile Thr Pro Met Asn Ala Asp Val Ile Val Leu Gly Leu Gln Ser
                 245                 250                 255

 Lys Asp Gln Ala Glu Gln Trp Leu Arg Val Ile Gln Glu Val Ser
                 260                 265                 270

 Gly Leu Pro Ser Glu Gly Ala Ser Glu Gly Asn Gln Tyr Thr Pro
                 275                 280                 285

 Asp Ala Gln Arg Phe Asn Cys Gln Lys Pro Asp Ile Ala Glu Lys
                 290                 295                 300

 Tyr Leu Ser Ala Ser Glu Tyr Gly Ser Ser Val Asp Gly His Pro
                 305                 310                 315

 Glu Val Pro Glu Thr Lys Asp Val Lys Lys Lys Cys Ser Ala Gly
                 320                 325                 330

 Leu Lys Leu Ser Asn Leu Met Asn Leu Gly Arg Lys Lys Ser Thr
                 335                 340                 345

 Ser Leu Glu Pro Val Glu Arg Ser Leu Glu Thr Ser Ser Tyr Leu
                 350                 355                 360

 Asn Val Leu Val Asn Ser Gln Trp Lys Ser Arg Trp Cys Ser Val
                 365                 370                 375

 Arg Asp Asn His Leu His Phe Tyr Gln Asp Arg Asn Arg Ser Lys
                 380                 385                 390

 Val Ala Gln Gln Pro Leu Ser Leu Val Gly Cys Glu Val Val Pro
                 395                 400                 405

 Asp Pro Ser Pro Asp His Leu Tyr Ser Phe Arg Ile Leu His Lys
                 410                 415                 420

 Gly Glu Glu Leu Ala Lys Leu Glu Ala Lys Ser Ser Glu Glu Met
                 425                 430                 435

 Gly His Trp Leu Gly Leu Leu Leu Ser Glu Ser Gly Ser Lys Thr
                 440                 445                 450

 Asp Pro Glu Glu Phe Thr Tyr Asp Tyr Val Asp Ala Asp Arg Val
                 455                 460                 465

 Ser Cys Ile Val Ser Ala Ala Lys Asn Ser Leu Leu Leu Met Gln
                 470                 475                 480

 Arg Lys Phe Ser Glu Pro Asn Thr Tyr Ile Asp Gly Leu Pro Ser
                 485                 490                 495

 Gln Asp Arg Gln Glu Glu Leu Tyr Asp Asp Val Asp Leu Ser Glu
                 500                 505                 510

 Leu Thr Ala Ala Val Glu Pro Thr Glu Glu Ala Thr Pro Val Ala
                 515                 520                 525

 Asp Asp Pro Asn Glu Arg Glu Ser Asp Arg Val Tyr Leu Asp Leu
                 530                 535                 540

 Thr Pro Val Lys Ser Phe Leu His Gly Pro Ser Ser Ala Gln Ala
                 545                 550                 555

 Gln Ala Ser Ser Pro Thr Leu Ser Cys Leu Asp Asn Ala Thr Glu
                 560                 565                 570

 Ala Leu Pro Ala Asp Ser Gly Pro Gly Pro Thr Pro Asp Glu Pro
                 575                 580                 585

 Cys Ile Lys Cys Pro Glu Asn Leu Gly Glu Gln Gln Leu Glu Ser
                 590                 595                 600

 Leu Glu Pro Glu Asp Pro Ser Leu Arg Ile Thr Thr Val Lys Ile
                 605                 610                 615

 Gln Thr Glu Gln Gln Arg Ile Ser Phe Pro Pro Ser Cys Pro Asp
                 620                 625                 630

 Ala Val Val Ala Thr Pro Pro Gly Ala Ser Pro Pro Val Lys Asp
                 635                 640                 645

 Arg Leu Arg Val Thr Ser Ala Glu Ile Lys Leu Gly Lys Asn Arg
                 650                 655                 660

 Thr Glu Ala Glu Val Lys Arg Tyr Thr Glu Glu Lys Glu Arg Leu
                 665                 670                 675

 Glu Lys Lys Lys Glu Glu Ile Arg Gly His Leu Ala Gln Leu Arg
                 680                 685                 690

 Lys Glu Lys Arg Glu Leu Lys Glu Thr Leu Leu Lys Cys Thr Asp
                 695                 700                 705

 Lys Glu Val Leu Ala Ser Leu Glu Gln Lys Leu Lys Glu Ile Asp
                 710                 715                 720

 Glu Glu Cys Arg Gly Glu Glu Ser Arg Arg Val Asp Leu Glu Leu
                 725                 730                 735

 Ser Ile Met Glu Val Lys Asp Asn Leu Lys Lys Ala Glu Ala Gly
                 740                 745                 750

 Pro Val Thr Leu Gly Thr Thr Val Asp Thr Thr His Leu Glu Asn
                 755                 760                 765

 Pro Lys Ala Val Thr Pro Ala Ser Ala Pro Asp Cys Thr Pro Val
                 770                 775                 780

 Asn Ser Ala Thr Thr Leu Lys Asn Arg Pro Leu Ser Val Val Val
                 785                 790                 795

 Thr Gly Lys Gly Thr Val Leu Gln Lys Ala Lys Glu Trp Glu Lys
                 800                 805                 810

 Lys Gly Ala Ser


<210> 6444
<211> 3145
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1518-1809, 1877-1894
<223> Unknown base

<400> 6444
 gggaaagcag caggttgggg cttcttgtgg ccaacttcag agcctgtcac 50

 caggaaaggt aagcatggga ggaaggaaga tggcgacaga tgaagaaaat 100

 gtctatggtt tagaagagcg ccactgggaa cagcatcctg ggccagagac 150

 ggttcttctc caggctgggg gccacgtctg tgaccaggcc tgcaccacgg 200

 gcagccgcag gtgggacaag tgccacgtgg aagtcgtgga cactccggac 250

 attttcagct cccaagtgtc caagacagat cctggctgtg aggagagagg 300

 tcactgctac ctgctctcgg cccccggacc ccacgcgctg ctcctggtga 350

 cccagttggg tcggttcacc gcccaggacc agcaggcggt gaggcaggtg 400

 agggacatgt tcggggagga cgtcctaaaa tggatggtca tcgtcttcac 450

 caggaaggag gacctggccg ggggctccct gcacgattac gtgagcaaca 500

 cagagaaccg ggccttgcgc gagctggtgg ccgagtgcgg gggccgggtc 550

 tgtgcctttg ataaccgggc caccggccgg gagcaggaag cccaggtgga 600

 gcagctgctg gggatggtcg agggcttggt gctggagcac aagggcgccc 650

 attactccaa cgaggtgtat gagctggcgc aggtgctgcg ctgggcaggc 700

 cctgaggagc ggctccggcg ggtggcggac gcgtggcagc cagggtgcag 750

 aggaggccat ggggcgcctg gctgtcggcc cggctgtgga agtggctgaa 800

 gtcccccagg agctggaggc tgggcctggc cctgctgctg gggggcgcgc 850

 tcctgttctg ggtgctgctc cacaggcggt ggtcggaggc cgttgcggag 900

 gtcgggcctg actgacagcg caggtcctaa aactgaaggc aacttggtta 950

 agggaggctg aattcttgga gctgaaggga aaacttcatt ccaacggaag 1000

 gaatcctgta gtttcaggca tagttttaat gacacagaaa actttgctgc 1050

 atcacctttg caactttgcc aaagctcaga gttcactttt taagttttta 1100

 actcatttta aatgatgtgt atgcagagtt ttaaaataaa ttcgtctaac 1150

 aataacttcc ttggtagttt tggtagtcta atgtcaagta gcttgtagtg 1200

 gggacaaacg catggcacag ggaaaacaag tgccattatt ttcgagcttt 1250

 ttaaaaaatt tagactgccc ctccttgata attttctagt tcttatacat 1300

 gggtagatag gttcctttgt gatccttgta gacttttagc atcaaaaaaa 1350

 gaaatgtggg ggttacacac gtgaatgtta cttctgagac atcagtttat 1400

 agtacaatga tttactacca aaaagatgaa tgtaactgta ctggtacaaa 1450

 gtgggaaata accgtttcca cttttctaga acatattatg gttcatggca 1500

 ttcccaaatg aagtaagnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1550

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1600

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1650

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1700

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1750

 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1800

 nnnnnnnnna agaaaaagag taggatattg ggaaaataac atataatatc 1850

 ttctatatgg ttattcatat ttttatnnnn nnnnnnnnnn nnnngtctgt 1900

 atctcgagct cctctctggt tatggagaag aggcagagca ccaggtgcat 1950

 aggctgagac tgcagacacc tgagcatcct atgctgtgag gcgaaagcat 2000

 ccggtttttt cgggatgggc ctgtccagga aggttctcga atgccacgtg 2050

 attagaaaat ttgccgctga ctggttgtgc gaatcaaaca ataggatttc 2100

 cttatttcta tttctgagca taatgagaac cctttaaggg aactcattgt 2150

 ctttaaatca gccagcctct agtgaggtca tggagacatg ggaagcaggt 2200

 attcacatta gctctattca agaggaagag gaggagggag tgtgcgcagg 2250

 cgccctaggg tcttccccag cacacgttgg gaagaagggg tctgcaagca 2300

 tgcgcacaat tgccagctca ggctaaggac tgcaggaggt tccaggtggg 2350

 ttgcgggctt cgggcaggct atggtgaggg gtcctgaggg ccttggtgac 2400

 cgctgcaggg agttggactt tttgaagcgt ggctcaagaa aaacccatgt 2450

 ttaattcctg cctttcgctt cctcagcagc ctttctgggc ccaggcaggg 2500

 gcctcgagcc aggaaggatc ctttgatgac cagaggggac agcagggagg 2550

 gcacagcgtg gtcgtccacg gtcacttgcg cacgagccag tgctgctgct 2600

 ggtgttagac aacaactttt atcaaagtgg tttaatgtac agcagcaaca 2650

 aagctgcttt gtggagcagg gctcccaata ggcagtgtgc ccagagtagc 2700

 agctcggaag cagtactgca atcacattta tacccacttt caactatatg 2750

 caaatttagg ggtggattat gccaaaattt ctagaaaaaa ggtcgtaact 2800

 tccaggtcgt gggattgttg ctatggaaag gagccaaaac ttccagctgt 2850

 tgccttagca atggtaacct gacgtggcac tggtgagtgt gttttatgga 2900

 gagactcttt cacctcttcc ctttcagctt gtcttcagtg tggtctggag 2950

 cccaatcccc acctccagag tctagtcctg cctcctacct cagtaataaa 3000

 aagtagtagt atatggttaa ttgtcaaata catttgcaaa gtgtaatcaa 3050

 agatacatta ccaatctgaa tctcaaaatg tgctatcatc tttgaatttg 3100

 aataatgtat tattaaagaa gttacagttt tcctttacat tcaat 3145

<210> 6445
<211> 265
<212> PRT
<213> Homo sapien

<220>
<221> Unsure
<222> 1518-1809, 1877-1894
<223> Unknown amino acid

<400> 6445
 Gly Lys Gln Gln Val Gly Ala Ser Cys Gly Gln Leu Gln Ser Leu
   1               5                  10                  15

 Ser Pro Gly Lys Val Ser Met Gly Gly Arg Lys Met Ala Thr Asp
                  20                  25                  30

 Glu Glu Asn Val Tyr Gly Leu Glu Glu Arg His Trp Glu Gln His
                  35                  40                  45

 Pro Gly Pro Glu Thr Val Leu Leu Gln Ala Gly Gly His Val Cys
                  50                  55                  60

 Asp Gln Ala Cys Thr Thr Gly Ser Arg Arg Trp Asp Lys Cys His
                  65                  70                  75

 Val Glu Val Val Asp Thr Pro Asp Ile Phe Ser Ser Gln Val Ser
                  80                  85                  90

 Lys Thr Asp Pro Gly Cys Glu Glu Arg Gly His Cys Tyr Leu Leu
                  95                 100                 105

 Ser Ala Pro Gly Pro His Ala Leu Leu Leu Val Thr Gln Leu Gly
                 110                 115                 120

 Arg Phe Thr Ala Gln Asp Gln Gln Ala Val Arg Gln Val Arg Asp
                 125                 130                 135

 Met Phe Gly Glu Asp Val Leu Lys Trp Met Val Ile Val Phe Thr
                 140                 145                 150

 Arg Lys Glu Asp Leu Ala Gly Gly Ser Leu His Asp Tyr Val Ser
                 155                 160                 165

 Asn Thr Glu Asn Arg Ala Leu Arg Glu Leu Val Ala Glu Cys Gly
                 170                 175                 180

 Gly Arg Val Cys Ala Phe Asp Asn Arg Ala Thr Gly Arg Glu Gln
                 185                 190                 195

 Glu Ala Gln Val Glu Gln Leu Leu Gly Met Val Glu Gly Leu Val
                 200                 205                 210

 Leu Glu His Lys Gly Ala His Tyr Ser Asn Glu Val Tyr Glu Leu
                 215                 220                 225

 Ala Gln Val Leu Arg Trp Ala Gly Pro Glu Glu Arg Leu Arg Arg
                 230                 235                 240

 Val Ala Asp Ala Trp Gln Pro Gly Cys Arg Gly Gly His Gly Ala
                 245                 250                 255

 Pro Gly Cys Arg Pro Gly Cys Gly Ser Gly
                 260                 265

<210> 6446
<211> 658
<212> DNA
<213> Homo sapien

<400> 6446
 agattaagga aggaaagata tgagaagcct gcagagcatg ctttcccaga 50

 ctgtatgggc ctgggaaagg agaagtggac agaaagggag cactaggtac 100

 ccctggaaga gaagattcat ccaagtcatc agggaagtta ctaatgcaag 150

 ggaaaaaatt tagagacagg gccaaacacg cttcttccaa gtcctttctg 200

 tctgctcagt cacctctatg cttatttttc ttctttcctc taagtagtgt 250

 catgcgtttt cttcctattc ctagtcgctc ctagtcaact aactcctctc 300

 tttaccatct tttcatcaga acttgaaacc tcctctcctt catgtattag 350

 tgatcatgtt tctccataat actgctagaa acaagaattg aaacctggaa 400

 aacctgcatt tgagaaccag atctccctct gctagctatt tgagaagtta 450

 ttttgttcca ttctttttgt tgaggtcctg tctcaaaaga aaacaaaaaa 500

 gataagaaaa agaaaactag ggaatctgga cagaataagt ttatatatat 550

 aataaagaac tgagatagaa ctgggttgac tgaataatta tttgagttgc 600

 ttttgagtga atttttccta ttggagtcta cctttgtttt tttgtgtgtg 650

 cgcagcgg 658

<210> 6447
<211> 31
<212> PRT
<213> Homo sapien

<400> 6447
 Arg Leu Arg Lys Glu Arg Tyr Glu Lys Pro Ala Glu His Ala Phe
   1               5                  10                  15

 Pro Asp Cys Met Gly Leu Gly Lys Glu Lys Trp Thr Glu Arg Glu
                  20                  25                  30

 His


<210> 6448
<211> 659
<212> DNA
<213> Homo sapien

<400> 6448
 acattctgct gttttattat gtcagtttcc taagtctgtg tttgaatatg 50

 atttttcacc atgctatcta tgtgtttttg tgtttgctgt gtatgagaag 100

 acatggtcta attattaggg gccaggcact gtgaacctat gcagaaaacc 150

 acaaaagtcc aaatctgcac tatccaatat ggtaactaca agtctcttgt 200

 agattttgag ctcttgctgt gaagctctga attgagatgt actacaagac 250

 ttcaaagagc tagtacaaaa aaagtaaaat atctcatgaa aaattgtata 300

 atatttttga ctactagaaa tatttagctg ctagaaattt ttaaatttca 350

 tatatgtgcc ttgcatttgt agtatacata atatttatat tgaatggcag 400

 gacaagtggc cactgtgagc ccaaagtaca catggaatat ttttgaaaag 450

 aagccaggag ttctagagct atagaatttc ctatctggaa gagatttcca 500

 aaagtaaata gtgtaaaagt gcttatattt gtccaacata gccctcactt 550

 tccaccacac acacgttaac acatgtaaat gtccatgcat gcaacactgt 600

 gaccagcata agcgaagagt tgctatacat taagagtttg gcatcactgg 650

 aagaatctc 659

<210> 6449
<211> 43
<212> PRT
<213> Homo sapien

<400> 6449
 Ile Leu Leu Phe Tyr Tyr Val Ser Phe Leu Ser Leu Cys Leu Asn
   1               5                  10                  15

 Met Ile Phe His His Ala Ile Tyr Val Phe Leu Cys Leu Leu Cys
                  20                  25                  30

 Met Arg Arg His Gly Leu Ile Ile Arg Gly Gln Ala Leu
                  35                  40

<210> 6450
<211> 1797
<212> DNA
<213> Homo sapien

<400> 6450
 gggggccggg tggaggggca aggcgagtgt gtgtccttat cctagcaatt 50

 ggggcgcggg cctgtgagcc agttggagtt gcggcggcgg gaacgattgg 100

 gctgagcaga ggacgacatg ttgcttttcg tggagcaggt agcatctaaa 150

 ggaactggtt taaatcctaa tgccaaagta tggcaagaaa ttgctcctgg 200

 aaatactgat gccaccccag taactcatgg aactgaaagc tcttggcatg 250

 aaatagcagc tacatcaggt gctcatcctg agggtaatgc agagctctca 300

 gaagatatat gtaaagaata tgaagtaatg tattcttcat cttgtgaaac 350

 cacaagaaat actacaggca ttgaagaatc aactgatggg atgattttag 400

 gaccagaaga tctgagttac caaatatatg atgtttccgg agaaagcaat 450

 tcagcagttt ctacagaaga cctaaaagaa tgtctgaaga aacaattaga 500

 attctgtttt tcacgagaaa atttgtcaaa ggatctttac ttgatatctc 550

 aaatggatag tgatcagttc atcccaattt ggacagttgc caacatggaa 600

 gaaataaaaa agttgactac agaccctgat ctaattcttg aagtgttaag 650

 atcttctccc atggtacaag ttgatgagaa gggtgagaaa gtgagaccaa 700

 gtcataagcg ttgtattgta attcttagag agattcctga aacaacacca 750

 atagaggaag tgaaaggttt gttcaaaagt gaaaactgcc ccaaagtgat 800

 aagctgtgag tttgcacaca atagcaactg gtatatcact ttccagtcag 850

 acacagatgc acaacaggct tttaaatact taagagaaga agttaaaaca 900

 tttcagggca agccaattat ggcaaggata aaagccatca atacattttt 950

 tgctaagaat ggttatcgat taatggattc tagtatctat agtcacccca 1000

 ttcaaactca agcacagtat gcctccccag tctttatgca gcctgtatat 1050

 aatcctcacc aacagtactc ggtctatagt attgtgcctc agtcttggtc 1100

 tccaaatcct acaccttact ttgaaacacc actggctccc tttcccaatg 1150

 gtagttttgt gaatggcttt aattcgccag gatcttataa aacaaatgct 1200

 gctgctatga atatgggtcg accattccaa aaaaatcgtg tgaagcctca 1250

 gtttaggtca tctggtggtt cagaacactc aacagagggc tctgtatcct 1300

 tgggggatgg acagttgaac agatatagtt caagaaactt tccagctgaa 1350

 cggcataacc ccacagtaac tgggcatcag gagcaaactt accttcagaa 1400

 ggagacttcc actttgcagg tggaacagaa tggggactat ggtaggggca 1450

 ggtaagaaaa taaagtacct gaaaaccttt gataataatg tgatcatcct 1500

 gaataattga agaacgtgat cttcataata attaaatgag catttaatta 1550

 ttggtatatg gttatattaa ataaatacgt tattttcaga acatgagttg 1600

 gttgcttttt ataattatta agaaatagag tgcccataca gaatatagct 1650

 ctgaatcaga ggtttataaa gttattctga agttccttat agctcatata 1700

 agaaagaata gcttagaaaa ttaacatatc catttgcctt atggttttaa 1750

 tttcttccag cttttaaact atagaagtgg ctgggtgcgg tggctca 1797

<210> 6451
<211> 445
<212> PRT
<213> Homo sapien

<400> 6451
 Met Leu Leu Phe Val Glu Gln Val Ala Ser Lys Gly Thr Gly Leu
   1               5                  10                  15

 Asn Pro Asn Ala Lys Val Trp Gln Glu Ile Ala Pro Gly Asn Thr
                  20                  25                  30

 Asp Ala Thr Pro Val Thr His Gly Thr Glu Ser Ser Trp His Glu
                  35                  40                  45

 Ile Ala Ala Thr Ser Gly Ala His Pro Glu Gly Asn Ala Glu Leu
                  50                  55                  60

 Ser Glu Asp Ile Cys Lys Glu Tyr Glu Val Met Tyr Ser Ser Ser
                  65                  70                  75

 Cys Glu Thr Thr Arg Asn Thr Thr Gly Ile Glu Glu Ser Thr Asp
                  80                  85                  90

 Gly Met Ile Leu Gly Pro Glu Asp Leu Ser Tyr Gln Ile Tyr Asp
                  95                 100                 105

 Val Ser Gly Glu Ser Asn Ser Ala Val Ser Thr Glu Asp Leu Lys
                 110                 115                 120

 Glu Cys Leu Lys Lys Gln Leu Glu Phe Cys Phe Ser Arg Glu Asn
                 125                 130                 135

 Leu Ser Lys Asp Leu Tyr Leu Ile Ser Gln Met Asp Ser Asp Gln
                 140                 145                 150

 Phe Ile Pro Ile Trp Thr Val Ala Asn Met Glu Glu Ile Lys Lys
                 155                 160                 165

 Leu Thr Thr Asp Pro Asp Leu Ile Leu Glu Val Leu Arg Ser Ser
                 170                 175                 180

 Pro Met Val Gln Val Asp Glu Lys Gly Glu Lys Val Arg Pro Ser
                 185                 190                 195

 His Lys Arg Cys Ile Val Ile Leu Arg Glu Ile Pro Glu Thr Thr
                 200                 205                 210

 Pro Ile Glu Glu Val Lys Gly Leu Phe Lys Ser Glu Asn Cys Pro
                 215                 220                 225

 Lys Val Ile Ser Cys Glu Phe Ala His Asn Ser Asn Trp Tyr Ile
                 230                 235                 240

 Thr Phe Gln Ser Asp Thr Asp Ala Gln Gln Ala Phe Lys Tyr Leu
                 245                 250                 255

 Arg Glu Glu Val Lys Thr Phe Gln Gly Lys Pro Ile Met Ala Arg
                 260                 265                 270

 Ile Lys Ala Ile Asn Thr Phe Phe Ala Lys Asn Gly Tyr Arg Leu
                 275                 280                 285

 Met Asp Ser Ser Ile Tyr Ser His Pro Ile Gln Thr Gln Ala Gln
                 290                 295                 300

 Tyr Ala Ser Pro Val Phe Met Gln Pro Val Tyr Asn Pro His Gln
                 305                 310                 315

 Gln Tyr Ser Val Tyr Ser Ile Val Pro Gln Ser Trp Ser Pro Asn
                 320                 325                 330

 Pro Thr Pro Tyr Phe Glu Thr Pro Leu Ala Pro Phe Pro Asn Gly
                 335                 340                 345

 Ser Phe Val Asn Gly Phe Asn Ser Pro Gly Ser Tyr Lys Thr Asn
                 350                 355                 360

 Ala Ala Ala Met Asn Met Gly Arg Pro Phe Gln Lys Asn Arg Val
                 365                 370                 375

 Lys Pro Gln Phe Arg Ser Ser Gly Gly Ser Glu His Ser Thr Glu
                 380                 385                 390

 Gly Ser Val Ser Leu Gly Asp Gly Gln Leu Asn Arg Tyr Ser Ser
                 395                 400                 405

 Arg Asn Phe Pro Ala Glu Arg His Asn Pro Thr Val Thr Gly His
                 410                 415                 420

 Gln Glu Gln Thr Tyr Leu Gln Lys Glu Thr Ser Thr Leu Gln Val
                 425                 430                 435

 Glu Gln Asn Gly Asp Tyr Gly Arg Gly Arg
                 440                 445

<210> 6452
<211> 2396
<212> DNA
<213> Homo sapien

<220>
<221> Unsure
<222> 1223-1238
<223> Unknown base

<400> 6452
 tttgtggttt attgatgcat caaagattcc ttagagataa atgcatataa 50

 aatgtgacca gaaaacattg gatttatgga gattatgcac ttggtgccca 100

 catttctcaa ggatgggaat gttgtgggag tgagagggat gttgcttcct 150

 ttataatcgt atacacagtt aatttcttat ttcctacttt gggcttctgc 200

 ctgctgcacc tgctgctatt ggcctattca tggtagctcc agccttcccc 250

 ttgacctcga tgtccctgcc atcaggacct tcacatgcca tcttgtgttc 300

 ccccaggagt ccctgtgtct aatgtgaatc tagagatccg gcccaccgga 350

 gggcagctga ttgaaggaga aaatatggtc cttatttgct cagtagccca 400

 gggttcaggg actgtcacat tctcctggca caaagaagga agagtaagaa 450

 gcctgggtag aaagacccag cgttccctgt tggcagagct gcatgttctc 500

 accgtgaagg agagtgatgc agggagatac tactgtgcag ctgataacgt 550

 tcacagcccc atcctcagca cgtggattcg agtcaccgtg agaattccgg 600

 tatctcaccc tgtcctcacc ttcagggctc ccagggccca cactgtggtg 650

 ggggacctgc tggagcttca ctgtgagtcc ctgagaggct ctcccccgat 700

 cctgtaccga ttttatcatg aggatgtcac cctggggaac agctcagccc 750

 cctctggagg aggagcctcc ttcaacctct ctctgactgc agaacattct 800

 ggaaactact cctgtgatgc agacaatggc ctgggggccc agcacagtca 850

 tggagtgagt ctcagggtca cagttccggt gtctcgcccc gtcctcaccc 900

 tcagggctcc cggggcccag gctgtggtgg gggacctgct ggagcttcac 950

 tgtgagtccc tgagaggctc cttcccgatc ctgtactggt tttatcacga 1000

 ggatgacacc ttggggaaca tctcggccca ctctggagga ggggcatcct 1050

 tcaacctctc tctgactaca gaacattctg gaaactactc atgtgaggct 1100

 gacaatggcc tgggggccca gcacagtaaa gtggtgacac tcaatgttac 1150

 aggaacttcc aggaacagaa caggccttac cgctgcggga atcacggggc 1200

 tggtgctcag catcctcgtc ctnnnnnnnn nnnnnnnnct gctgcattac 1250

 gccagggccc gaaggaaacc aggaggactt tctgccactg gaacatctag 1300

 tcacagtcct agtgagtgtc aggagccttc ctcgtccagg ccttccagga 1350

 tagaccctca agagcccact cactctaaac cactagcccc aatggagctg 1400

 gagccaatgt acagcaatgt aaatcctgga gatagcaacc cgatttattc 1450

 ccagatctgg agcatccagc atacaaaaga aaactcagct aattgtccaa 1500

 tgatgcatca agagcatgag gaacttacag tcctctattc agaactgaag 1550

 aagacacacc cagacgactc tgcaggggag gctagcagca gaggcagggc 1600

 ccatgaagaa gatgatgaag aaaactatga gaatgtacca cgtgtattac 1650

 tggcctcaga ccactagccc cttacccaga gtggcccaca ggaaacagcc 1700

 tgcaccattt ttttttctgt tctctccaac cacacatcat ccatctctcc 1750

 agactctgcc tcctacgagg ctgggctgca gggtatgtga ggctgagcaa 1800

 aaggtctgca aatctcccct gtgcctgatc tgtgtgttcc ccaggaagag 1850

 agcaggcagc ctctgagcaa gcactgtgtt attttcacag tggagacacg 1900

 tggcaaggca ggagggccct cagctcctag ggctgtcgaa tagaggagga 1950

 gagagaaatg gtctagccag ggttacaagg gcacaatcat gaccatttga 2000

 tccaagtgtg atcgaaagct gttaatgtgc tctctgtata aacaatttgc 2050

 tccaaatatt ttgtttccct tttttgtgtg gctggtagtg gcattgctga 2100

 tgttttggtg tatatgctgt atccttgcta ccatattggg aacagccaaa 2150

 agaagttata gaacaagaat ttaaggtgac tctatctgaa gtgtattttt 2200

 gtacttacag ggtgacattc ccaaccaaat taccctagtt atgatgaaaa 2250

 ataacttcag catttcatta aagactctgc tagtttaata tgtgacttgt 2300

 atccccactg caaagacctt atgtgtgaag aatcacatta attgtaattt 2350

 ttgcttcatg acatagtctc atcattttcc atacatgata gatttc 2396

<210> 6453
<211> 460
<212> PRT
<213> Homo sapien

<220>
<221> unsure
<222> 314-318
<223> unknown amino acid

<220>
<221> Unsure
<222> 1223-1238
<223> Unknown amino acid

<400> 6453
 Met Pro Ser Cys Val Pro Pro Gly Val Pro Val Ser Asn Val Asn
   1               5                  10                  15

 Leu Glu Ile Arg Pro Thr Gly Gly Gln Leu Ile Glu Gly Glu Asn
                  20                  25                  30

 Met Val Leu Ile Cys Ser Val Ala Gln Gly Ser Gly Thr Val Thr
                  35                  40                  45

 Phe Ser Trp His Lys Glu Gly Arg Val Arg Ser Leu Gly Arg Lys
                  50                  55                  60

 Thr Gln Arg Ser Leu Leu Ala Glu Leu His Val Leu Thr Val Lys
                  65                  70                  75

 Glu Ser Asp Ala Gly Arg Tyr Tyr Cys Ala Ala Asp Asn Val His
                  80                  85                  90

 Ser Pro Ile Leu Ser Thr Trp Ile Arg Val Thr Val Arg Ile Pro
                  95                 100                 105

 Val Ser His Pro Val Leu Thr Phe Arg Ala Pro Arg Ala His Thr
                 110                 115                 120

 Val Val Gly Asp Leu Leu Glu Leu His Cys Glu Ser Leu Arg Gly
                 125                 130                 135

 Ser Pro Pro Ile Leu Tyr Arg Phe Tyr His Glu Asp Val Thr Leu
                 140                 145                 150

 Gly Asn Ser Ser Ala Pro Ser Gly Gly Gly Ala Ser Phe Asn Leu
                 155                 160                 165

 Ser Leu Thr Ala Glu His Ser Gly Asn Tyr Ser Cys Asp Ala Asp
                 170                 175                 180

 Asn Gly Leu Gly Ala Gln His Ser His Gly Val Ser Leu Arg Val
                 185                 190                 195

 Thr Val Pro Val Ser Arg Pro Val Leu Thr Leu Arg Ala Pro Gly
                 200                 205                 210

 Ala Gln Ala Val Val Gly Asp Leu Leu Glu Leu His Cys Glu Ser
                 215                 220                 225

 Leu Arg Gly Ser Phe Pro Ile Leu Tyr Trp Phe Tyr His Glu Asp
                 230                 235                 240

 Asp Thr Leu Gly Asn Ile Ser Ala His Ser Gly Gly Gly Ala Ser
                 245                 250                 255

 Phe Asn Leu Ser Leu Thr Thr Glu His Ser Gly Asn Tyr Ser Cys
                 260                 265                 270

 Glu Ala Asp Asn Gly Leu Gly Ala Gln His Ser Lys Val Val Thr
                 275                 280                 285

 Leu Asn Val Thr Gly Thr Ser Arg Asn Arg Thr Gly Leu Thr Ala
                 290                 295                 300

 Ala Gly Ile Thr Gly Leu Val Leu Ser Ile Leu Val Leu Xaa Xaa
                 305                 310                 315

 Xaa Xaa Xaa Leu Leu His Tyr Ala Arg Ala Arg Arg Lys Pro Gly
                 320                 325                 330

 Gly Leu Ser Ala Thr Gly Thr Ser Ser His Ser Pro Ser Glu Cys
                 335                 340                 345

 Gln Glu Pro Ser Ser Ser Arg Pro Ser Arg Ile Asp Pro Gln Glu
                 350                 355                 360

 Pro Thr His Ser Lys Pro Leu Ala Pro Met Glu Leu Glu Pro Met
                 365                 370                 375

 Tyr Ser Asn Val Asn Pro Gly Asp Ser Asn Pro Ile Tyr Ser Gln
                 380                 385                 390

 Ile Trp Ser Ile Gln His Thr Lys Glu Asn Ser Ala Asn Cys Pro
                 395                 400                 405

 Met Met His Gln Glu His Glu Glu Leu Thr Val Leu Tyr Ser Glu
                 410                 415                 420

 Leu Lys Lys Thr His Pro Asp Asp Ser Ala Gly Glu Ala Ser Ser
                 425                 430                 435

 Arg Gly Arg Ala His Glu Glu Asp Asp Glu Glu Asn Tyr Glu Asn
                 440                 445                 450

 Val Pro Arg Val Leu Leu Ala Ser Asp His
                 455                 460

<210> 6454
<211> 2318
<212> DNA
<213> Homo sapien

<400> 6454
 gtgtgtgtgt gtgtgtgtgt gagagagaga gatgtgttgg ggtgggggga 50

 ctgcaggtca ggaagtcctg cagatgtgcg tgcctgtgtg tgtttgcgcg 100

 cgcgcgcgcg tgtgtgtgtg tctgtgtgtg tgcctggagc tgcgcttgca 150

 ggtctgagag tcctctgaga atgggttggg ggaggcgggt gcaggaccga 200

 ggcctggaac agccaacaaa gaggccctgg aggagggtgg ggctggccgg 250

 ggacaggagg ggtggccaag aaagtcgcaa gaaaactccg gcccccaaga 300

 aaaagagagg gcatgggttg cggagccgac atcacggccg gggtctttgc 350

 tgtttagacg cctgggttcc cggatcccag acacgcgcac gggcaggaag 400

 ttagaccgga gacagcgagt atagacagcc cttctggata ggggcagacg 450

 gcccgggttt ccgcttccct ccgggcgcga gaagagggga gccaggccga 500

 gccccggccc taccgccgcc gccgccatgt ggcccccaga ccccgacccc 550

 gacccggacc ccgagcctgc cggcggctcc cgtcccggcc ccgcggtccc 600

 cgggctccgc gccctgctgc cggcgcgggc tttcctctgc tctctcaaag 650

 gccgcctcct gctggccgag tcgggtctct cattcatcac ttttatctgc 700

 tatgtggcgt cctcagcatc tgccttcctc acagcgcctc tgctggagtt 750

 cctgctggcc ttgtacttcc tctttgctga tgccatgcag ctgaatgaca 800

 agtggcaggg cttgtgctgg cccatgatgg acttcctgcg ctgtgtcacc 850

 gcggccctca tctactttgc tatctccatc acggccatcg ccaagtactc 900

 ggatggggct tccaaagccg ctggggtgtt tggcttcttt gctaccatcg 950

 tgtttgcaac tgatttctac ctgatcttta acgacgtggc caaattcctc 1000

 aaacaagggg actctgcaga tgagaccaca gcccacaaga cagaagaaga 1050

 gaattccgac tcggactctg actgaaggcc tggcgggtgc cttggcaacc 1100

 tgagccacac aggcctccac ccctgcgcct cacaggggtc gctggcgttg 1150

 gagcggaggc ctggacttct gagttgcaga gggggctgcg gacacagcag 1200

 gccccctaca gcctcaggtt ctgcctgagc ccagcctacc aggcttgccc 1250

 ctcagctcag cactgttgac cacgctgcgt atgagggcat cttgggtatc 1300

 ccactccttc tccccatttc tgtcccacag gccttcagcc ctttaacgtc 1350

 tctgccaaaa accagcacaa ggagacaaag cagagccttg tctgtatctg 1400

 ggcagcaggt gttccatgct gctaggtggc gggggtcggg ggtcttctgt 1450

 ttcactaaca ggaacaaaga cagaaaccat gacagggctg ccccgccagg 1500

 ccccggtggg tttgtctgca cttggtgctc ctgcccacac cagccacttt 1550

 ggtgacaatg acccttccaa gaatctttgg ttcaaggagc accagttccc 1600

 tcttcattct tgaagcaggg agaaattgac ctttgccttg tcgcccagga 1650

 agtggggctc ggcacccata actaacacct cccacccttg gaaaccatgt 1700

 cttctggggg tgagatgacc attctgggtc taagactgtt tcaaagaaga 1750

 gctcatagac tgactggtcc agaagacaga gggtacaaca gtggcatcac 1800

 agtgacagtg tcatggggag ctgggcgggc ccagccaaac cctccttctt 1850

 cctagagccc agccagcagg caggagttcc tggaccctca ggacagtgaa 1900

 cttccagacc tcagggcagg tctatgggcc actgcaggag atgagaccag 1950

 ccttctgtgt tcacctaacg atttatactg tgtatctgtc tttgatggaa 2000

 ttttgtaact ttttatattt ttttatgcaa aagcagcttc ttaacagatg 2050

 gcattttctg tgactctagg cctcacaaaa gagccagagt tctggaccca 2100

 tgtttggagc atttgtagcc ttattctctt gcgtgtgaat ctcttaccct 2150

 gaaaaaaagc cataatgaat taagccagac tgaccacttg cttggagtgt 2200

 gtgcttgaaa aaaccagagc aatactgttg ggtattgtat caggcttcag 2250

 tacaaactgg taacaccaat gtggatcctg acagctttca gttttagcaa 2300

 aaatacacgt gaaatctg 2318

<210> 6455
<211> 182
<212> PRT
<213> Homo sapien

<400> 6455
 Met Trp Pro Pro Asp Pro Asp Pro Asp Pro Asp Pro Glu Pro Ala
   1               5                  10                  15

 Gly Gly Ser Arg Pro Gly Pro Ala Val Pro Gly Leu Arg Ala Leu
                  20                  25                  30

 Leu Pro Ala Arg Ala Phe Leu Cys Ser Leu Lys Gly Arg Leu Leu
                  35                  40                  45

 Leu Ala Glu Ser Gly Leu Ser Phe Ile Thr Phe Ile Cys Tyr Val
                  50                  55                  60

 Ala Ser Ser Ala Ser Ala Phe Leu Thr Ala Pro Leu Leu Glu Phe
                  65                  70                  75

 Leu Leu Ala Leu Tyr Phe Leu Phe Ala Asp Ala Met Gln Leu Asn
                  80                  85                  90

 Asp Lys Trp Gln Gly Leu Cys Trp Pro Met Met Asp Phe Leu Arg
                  95                 100                 105

 Cys Val Thr Ala Ala Leu Ile Tyr Phe Ala Ile Ser Ile Thr Ala
                 110                 115                 120

 Ile Ala Lys Tyr Ser Asp Gly Ala Ser Lys Ala Ala Gly Val Phe
                 125                 130                 135

 Gly Phe Phe Ala Thr Ile Val Phe Ala Thr Asp Phe Tyr Leu Ile
                 140                 145                 150

 Phe Asn Asp Val Ala Lys Phe Leu Lys Gln Gly Asp Ser Ala Asp
                 155                 160                 165

 Glu Thr Thr Ala His Lys Thr Glu Glu Glu Asn Ser Asp Ser Asp
                 170                 175                 180

 Ser Asp


<210> 6456
<211> 1291
<212> DNA
<213> Homo sapien

<400> 6456
 aaaaaaacaa aaaacaaaac aaaaaaaaaa ccttccaaaa gaagtttgag 50

 ataattttat gtttagaaaa attagaaatt ggattgagta aaatttacat 100

 attttacaca agaggactaa catctttata atatttaacc tttcagtaaa 150

 tttatgtttt atgtttctca gcctatcttt tctagtatag gtgatttttt 200

 tagtgtggtt actattgtaa atgagatcct actactttaa aaaatgaaaa 250

 ttaaatctat cgcttttatg actttaaaac attagactta tgtaagtgta 300

 aacattattt aaaaacataa tgtagaaaat taaagtcccc cataattaaa 350

 atccctttcc cccagaaaaa gtcaacagca tattcatcag ttttttccta 400

 aagtatgttt tagcactttg accatatgag acaacccttc tgctgttagc 450

 atttttctct ttgcaataga tcttcctatg tcagtacaca tcaatctacc 500

 tcattcttac ctctgcataa gagagtagtg tgtagttgta taatagttta 550

 acttggcgat tggttattga ttttgtaact agccagttac tgaattattc 600

 taaaggtttt gctgttgtta atttctttcg cctttttcag ttgggtaata 650

 gttctgggta ggttgataat tttattccca tatttgtaat cttatttcac 700

 tttctcaact catcacattg actggtactt ttagaacaat gttaaaaaac 750

 atttacataa ttgtgctgat attgtacatt atttgatata tatatatttt 800

 ttttacttag aagagtgttt ctccaaaact ataaatttga ctcttagtgt 850

 aaaataatct taatatttga attatacatt caggttatgc cctctatttc 900

 tagtttgatg aaaatattat tagtaatgga tgttggggtt ttattaaatg 950

 gcttttttcc acatctgtca agatgatcaa ctggcttttc tctattatga 1000

 ctttagatga atcgttttaa tagatttgct aatgttaaga catctctgca 1050

 tttctacaag aatctgatgt agtcatagta tactattctt ttaatataca 1100

 tctcctttca atgttaacag tggttattta tgattggttg gtccatagta 1150

 gatttttatt ttgtgtttct tatctgtact ttctgatttt tctacaaaga 1200

 ttgtgtatta cttgtataat aaaaataaga gctttaaatt gtgaaattct 1250

 tctggatttg gttttctcat tttattatgg aatttttcat a 1291

<210> 6457
<211> 1797
<212> DNA
<213> Homo sapien

<400> 6457
 gccaagctgc gcgggcagaa gcggtccggg gcctccgcgg ccccgcggcc 50

 tccgcggccg ctgccttggc acccagcgcc acccgcacac ggcgctccgc 100

 tacgccagtg cctgggatgc aacgagccat gtgctggtgt gagaagccgc 150

 ctgtcggaga agcctgcgtg ctgagtgctg ctcgtctgcc tgcggtgccc 200

 acgtgaggat gtggccctgg tggtgacgcc tgccgccgcc tgatgcttgg 250

 ctgttgctcc cgccacccgc ctgcctgccg ccgccgactc ccgcgacccc 300

 gacgtcctcg gcgtccaacc tggacctggg cgagcagcgg gagcgctggg 350

 agacgttcca gaagcggcag aagcttacct ccgagggtgc cgccaagctc 400

 ctgctagaca cctttgaata ccagggcctg gtgaagcaca caggaggctg 450

 ccactgtgga gcagttcgtt ttgaagtttg ggcctcagca gacttgcata 500

 tatttgactg caagtaccgg aattatatat gaataataag cacatacgat 550

 ggaattactc aaatggagaa ctgaccaggc tactaacaat agagtccaga 600

 ttggaaaaga agcactgtgg aataacttgt gagaggattc tgtgctaaat 650

 tagaactttt tcaaaggtgg cctgaaaaga ggggacttca gtttaattcc 700

 agagatggta attctgggga cgtgttttac ttggagctgg acttcttgtg 750

 acgtggtgat gaagaaagag ggaaacctaa acttccttgt ccatttttgg 800

 tgtggatgtc tcagagacat caggttgtag cagtgtctga aatttgtttc 850

 ctaagtgtct ctgaagtcca gcgcttctct tcactgtaaa gaactgaggg 900

 gtgggcagta cagacctgtc tgttggtcct gtgttctgag cattgcagaa 950

 cctcgactgc tgacttggga cccccctggg ctctgctgta cctgcaaacc 1000

 agaggcactg ctatccaggc ctttgcccca gctcctcggc cctggatggt 1050

 gctgaaaggg gcatcatctg tggggtcggc tggctctcat ggctgggccg 1100

 ctcaggcata gaggatgcag gtggctgctc acaatctgga atttgctctg 1150

 tctttctgta gttgcagcat ttgcaagaag aagcagaata gacacttcat 1200

 tgttccagct tctcgcttca agctcctgaa gggagctgag cacataacga 1250

 cttacacgtt caatactcac aaagcccagc ataccttctg taagagatgt 1300

 ggcgttcaga gcttctatac tccacgatca aaccccggag gcttcggaat 1350

 tgccccccac tgcctggatg agggcactgt gcggagtatg gtcactgagg 1400

 aattcaatgg cagcgattgg gagaaggcca tgaaagagca caagaccatc 1450

 aagaacatgt ctaaagagtg agcttctgcc tctcctgccc tgaaaaggag 1500

 gaatgattgg ggccagcaac tttgctctcc ctgccgtgcc tcggtggtgc 1550

 tcctgaatgt ggctgacctg ggctgctggt tccgttgact agggtcatct 1600

 tgatctctgc agtttgctcc agctaccagt ttctttaggc agctctttgt 1650

 cctccctctg cccagatttt gatgtagtct aattgacatc cttctcttcc 1700

 caacttttgt gtgatctttt aggaaaaaaa ataaatattt ttaacattaa 1750

 agcaaaaaaa atctatgtcg ggtgcggaga aagaggtaat ggaaatg 1797

<210> 6458
<211> 67
<212> PRT
<213> Homo sapien

<400> 6458
 Gln Ala Ala Arg Ala Glu Ala Val Arg Gly Leu Arg Gly Pro Ala
   1               5                  10                  15

 Ala Ser Ala Ala Ala Ala Leu Ala Pro Ser Ala Thr Arg Thr Arg
                  20                  25                  30

 Arg Ser Ala Thr Pro Val Pro Gly Met Gln Arg Ala Met Cys Trp
                  35                  40                  45

 Cys Glu Lys Pro Pro Val Gly Glu Ala Cys Val Leu Ser Ala Ala
                  50                  55                  60

 Arg Leu Pro Ala Val Pro Thr
                  65

<210> 6459
<211> 602
<212> DNA
<213> Homo sapien

<400> 6459
 gacgcggggc cggaacgcga agagggtggt ggagtcgggc tacccactga 50

 ttttccttcc cttacttccc ctgagccctt gggcccactt cccagcctac 100

 cgcttccgtc cccgcccgac tcttgggcca gcgcctgggc ccacactttc 150

 ctatcccccg cagatgccgg tggccgtggg tccctacgga cagtcccagc 200

 caagctgctt cgaccgtgtc aaaatgggct tcgtgatggg ttgcgccgtg 250

 ggcatggcgg ccggggcgct cttcggcacc ttttcctgtc tcaggatcgg 300

 aatgcggggt cgagagctga tgggcggcat tgggaaaacc atgatgcaga 350

 gtggcggcac ctttggcaca ttcatggcca ttgggatggg catccgatgc 400

 taaccatggt tgccaactac atctgtccct tcccatcaat cccagcccat 450

 gtactaataa aagaaagtct ttgagtaaaa aaaaaaaaaa aaaaaaaaaa 500

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 550

 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 600

 aa 602

<210> 6460
<211> 79
<212> PRT
<213> Homo sapien

<400> 6460
 Met Pro Val Ala Val Gly Pro Tyr Gly Gln Ser Gln Pro Ser Cys
   1               5                  10                  15

 Phe Asp Arg Val Lys Met Gly Phe Val Met Gly Cys Ala Val Gly
                  20                  25                  30

 Met Ala Ala Gly Ala Leu Phe Gly Thr Phe Ser Cys Leu Arg Ile
                  35                  40                  45

 Gly Met Arg Gly Arg Glu Leu Met Gly Gly Ile Gly Lys Thr Met
                  50                  55                  60

 Met Gln Ser Gly Gly Thr Phe Gly Thr Phe Met Ala Ile Gly Met
                  65                  70                  75

 Gly Ile Arg Cys


<210> 6461
<211> 350
<212> DNA
<213> Homo sapien

<400> 6461
 atggtataag attaaatata ttagttatga aaataattgt aaatggctta 50

 ttgaacttat agtcagtaaa aatcatgttt ttgaaaatta tgtaatgact 100

 ttggaaaata ccagcaatat aatgttaagt ggggaaaaaa gcaagttact 150

 cctctgtaat acatatgatt ttagttttgt aataaaaatt cccaaccata 200

 tatgcactta tagggaaaca aaggacccat cgcaaatgtt ttccatgctg 250

 atctccaaag tggtgagttt atgtgtgatt tttattttgt ttatgctctt 300

 ctgtattttc cgaatttcat acaataaata tctgttactt ttacaatatg 350

<210> 6462
<211> 115
<212> PRT
<213> Homo sapien

<400> 6462
 Trp Tyr Lys Ile Lys Tyr Ile Ser Tyr Glu Asn Asn Cys Lys Trp
   1               5                  10                  15

 Leu Ile Glu Leu Ile Val Ser Lys Asn His Val Phe Glu Asn Tyr
                  20                  25                  30

 Val Met Thr Leu Glu Asn Thr Ser Asn Ile Met Leu Ser Gly Glu
                  35                  40                  45

 Lys Ser Lys Leu Leu Leu Cys Asn Thr Tyr Asp Phe Ser Phe Val
                  50                  55                  60

 Ile Lys Ile Pro Asn His Ile Cys Thr Tyr Arg Glu Thr Lys Asp
                  65                  70                  75

 Pro Ser Gln Met Phe Ser Met Leu Ile Ser Lys Val Val Ser Leu
                  80                  85                  90

 Cys Val Ile Phe Ile Leu Phe Met Leu Phe Cys Ile Phe Arg Ile
                  95                 100                 105

 Ser Tyr Asn Lys Tyr Leu Leu Leu Leu Gln
                 110                 115

<210> 6463
<211> 313
<212> DNA
<213> Homo sapien

<400> 6463
 ctcagactga cactgttaca aactagcatc ttcagatgca tggtatttac 50

 tttaaatgtg cttatataca gtgtagagaa gctcttgtat aagaagacat 100

 ctatgctagc taacttagta gtagtagagg gaacatattc agtgagctgc 150

 ctttatatct gtagtgtcgg agacttgtta ctggttcatt tgtggttatc 200

 agttgaaggt tctgttcctg agatgtgcaa tagtagtgtt gaaaggtatt 250

 gtttaatagt gatggggaac agacatattg gacttttttt tccatattaa 300

 attatttagt ttg 313

<210> 6464
<211> 99
<212> PRT
<213> Homo sapien

<400> 6464
 Leu Arg Leu Thr Leu Leu Gln Thr Ser Ile Phe Arg Cys Met Val
   1               5                  10                  15

 Phe Thr Leu Asn Val Leu Ile Tyr Ser Val Glu Lys Leu Leu Tyr
                  20                  25                  30

 Lys Lys Thr Ser Met Leu Ala Asn Leu Val Val Val Glu Gly Thr
                  35                  40                  45

 Tyr Ser Val Ser Cys Leu Tyr Ile Cys Ser Val Gly Asp Leu Leu
                  50                  55                  60

 Leu Val His Leu Trp Leu Ser Val Glu Gly Ser Val Pro Glu Met
                  65                  70                  75

 Cys Asn Ser Ser Val Glu Arg Tyr Cys Leu Ile Val Met Gly Asn
                  80                  85                  90

 Arg His Ile Gly Leu Phe Phe Pro Tyr
                  95

